# --- full sequence ---- --- best 1 domain ---- --- domain number estimation ---- # target name accession query name accession E-value score bias E-value score bias exp reg clu ov env dom rep inc description of target #------------------- ---------- -------------------- ---------- --------- ------ ----- --------- ------ ----- --- --- --- --- --- --- --- --- --------------------- F-box PF00646.28 KLO03704.1 - 7.4e-05 22.2 0.1 0.00011 21.7 0.0 1.3 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 KLO03704.1 - 0.049 13.3 0.0 0.069 12.8 0.0 1.3 1 0 0 1 1 1 0 F-box-like zf-CCHC PF00098.18 KLO03705.1 - 0.01 15.7 2.9 0.019 14.8 2.0 1.5 1 0 0 1 1 1 0 Zinc knuckle Adaptin_binding PF10199.4 KLO03705.1 - 0.42 10.8 7.7 0.7 10.1 5.3 1.3 1 0 0 1 1 1 0 Alpha and gamma adaptin binding protein p34 CDC45 PF02724.9 KLO03705.1 - 0.47 8.4 8.4 0.61 8.0 5.8 1.1 1 0 0 1 1 1 0 CDC45-like protein Pex16 PF08610.5 KLO03705.1 - 2.6 6.9 5.4 5.9 5.7 3.5 1.7 1 1 1 2 2 2 0 Peroxisomal membrane protein (Pex16) DNA_pol_phi PF04931.8 KLO03705.1 - 5.2 4.7 11.4 7 4.2 7.9 1.1 1 0 0 1 1 1 0 DNA polymerase phi SDP_N PF12278.3 KLO03706.1 - 0.057 13.0 0.0 0.12 12.0 0.0 1.4 1 0 0 1 1 1 0 Sex determination protein N terminal WD40 PF00400.27 KLO03707.1 - 1.5e-31 107.0 11.7 2.6e-11 42.9 0.5 3.7 4 0 0 4 4 4 3 WD domain, G-beta repeat PD40 PF07676.7 KLO03707.1 - 0.00034 20.1 0.2 1.1 8.9 0.0 3.2 3 0 0 3 3 3 2 WD40-like Beta Propeller Repeat Nup160 PF11715.3 KLO03707.1 - 0.0072 14.5 1.0 0.66 8.0 0.1 2.7 1 1 1 2 2 2 2 Nucleoporin Nup120/160 eIF2A PF08662.6 KLO03707.1 - 0.012 15.2 0.0 0.021 14.5 0.0 1.3 1 0 0 1 1 1 0 Eukaryotic translation initiation factor eIF2A Gmad1 PF10647.4 KLO03707.1 - 0.014 14.8 1.4 0.023 14.1 1.0 1.3 1 0 0 1 1 1 0 Lipoprotein LpqB beta-propeller domain Nbas_N PF15492.1 KLO03707.1 - 0.023 13.7 0.5 0.26 10.3 0.0 2.4 1 1 1 2 2 2 0 Neuroblastoma-amplified sequence, N terminal Zn_clus PF00172.13 KLO03709.1 - 2.3e-09 37.0 22.8 8.1e-05 22.4 5.1 2.1 2 0 0 2 2 2 2 Fungal Zn(2)-Cys(6) binuclear cluster domain Gly_kinase PF02595.10 KLO03709.1 - 0.09 11.4 0.2 0.12 11.0 0.1 1.2 1 0 0 1 1 1 0 Glycerate kinase family Cytochrome_C7 PF14522.1 KLO03709.1 - 4.8 6.8 18.0 1.5 8.5 8.6 2.2 1 1 1 2 2 2 0 Cytochrome c7 FSH1 PF03959.8 KLO03713.1 - 0.049 13.0 0.0 0.069 12.5 0.0 1.4 1 0 0 1 1 1 0 Serine hydrolase (FSH1) DUF1556 PF07590.6 KLO03714.1 - 0.19 11.9 1.3 0.43 10.8 0.9 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1556) zf-CCHC PF00098.18 KLO03716.1 - 0.003 17.3 2.0 0.0054 16.6 1.4 1.4 1 0 0 1 1 1 1 Zinc knuckle Adaptin_binding PF10199.4 KLO03716.1 - 0.015 15.5 10.8 0.027 14.7 7.5 1.4 1 0 0 1 1 1 0 Alpha and gamma adaptin binding protein p34 CDC45 PF02724.9 KLO03716.1 - 0.032 12.2 12.3 0.034 12.1 8.5 1.1 1 0 0 1 1 1 0 CDC45-like protein YL1 PF05764.8 KLO03716.1 - 0.04 13.5 17.7 0.05 13.1 12.3 1.1 1 0 0 1 1 1 0 YL1 nuclear protein DUF4636 PF15468.1 KLO03716.1 - 0.16 11.4 3.5 0.21 10.9 2.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4636) Secretin_N_2 PF07655.8 KLO03716.1 - 1.2 9.6 6.9 1.7 9.0 4.8 1.2 1 0 0 1 1 1 0 Secretin N-terminal domain Nop14 PF04147.7 KLO03716.1 - 2.5 5.9 22.4 6.1 4.6 15.7 1.5 1 1 1 2 2 2 0 Nop14-like family Ebola_NP PF05505.7 KLO03716.1 - 4.2 5.3 9.3 4.9 5.0 6.5 1.0 1 0 0 1 1 1 0 Ebola nucleoprotein DNA_pol_phi PF04931.8 KLO03716.1 - 4.4 4.9 14.1 4.9 4.7 9.8 1.1 1 0 0 1 1 1 0 DNA polymerase phi SDA1 PF05285.7 KLO03716.1 - 7.3 5.7 18.6 9.7 5.3 12.9 1.2 1 0 0 1 1 1 0 SDA1 AF-4 PF05110.8 KLO03717.1 - 0.0028 15.6 11.7 0.0028 15.6 8.1 1.7 2 0 0 2 2 2 1 AF-4 proto-oncoprotein zf-CCHC PF00098.18 KLO03717.1 - 0.0059 16.4 2.0 0.01 15.7 1.4 1.4 1 0 0 1 1 1 1 Zinc knuckle Adaptin_binding PF10199.4 KLO03717.1 - 0.011 15.9 10.8 0.024 14.9 7.5 1.5 1 0 0 1 1 1 0 Alpha and gamma adaptin binding protein p34 CDC45 PF02724.9 KLO03717.1 - 0.025 12.6 13.8 0.032 12.3 9.6 1.1 1 0 0 1 1 1 0 CDC45-like protein BUD22 PF09073.5 KLO03717.1 - 0.052 12.6 20.0 0.69 8.9 12.4 2.2 2 0 0 2 2 2 0 BUD22 Secretin_N_2 PF07655.8 KLO03717.1 - 0.12 12.7 2.5 0.23 11.8 1.7 1.3 1 0 0 1 1 1 0 Secretin N-terminal domain CENP-B_dimeris PF09026.5 KLO03717.1 - 0.22 11.7 9.8 0.5 10.6 6.8 1.6 1 0 0 1 1 1 0 Centromere protein B dimerisation domain YL1 PF05764.8 KLO03717.1 - 0.25 10.9 22.7 0.084 12.4 13.5 1.7 2 0 0 2 2 2 0 YL1 nuclear protein Ebola_NP PF05505.7 KLO03717.1 - 2.6 6.0 8.4 3.6 5.5 5.8 1.1 1 0 0 1 1 1 0 Ebola nucleoprotein Sigma70_ner PF04546.8 KLO03717.1 - 2.7 7.5 12.5 4.5 6.8 8.6 1.3 1 0 0 1 1 1 0 Sigma-70, non-essential region Nop14 PF04147.7 KLO03717.1 - 5 4.9 24.7 11 3.8 17.2 1.4 1 1 1 2 2 2 0 Nop14-like family SDA1 PF05285.7 KLO03717.1 - 8.2 5.6 21.1 13 4.9 14.6 1.2 1 0 0 1 1 1 0 SDA1 KOW PF00467.24 KLO03719.1 - 1.9e-09 36.8 13.4 0.023 14.4 0.0 4.3 4 0 0 4 4 4 3 KOW motif DUF4438 PF14505.1 KLO03719.1 - 0.0085 14.8 2.5 3.6 6.2 0.0 2.9 2 1 0 3 3 3 2 Domain of unknown function (DUF4438) AraC_binding_2 PF14525.1 KLO03719.1 - 0.079 12.5 0.1 3.6 7.1 0.0 2.2 1 1 0 2 2 2 0 AraC-binding-like domain RNase_H PF00075.19 KLO03721.1 - 0.00028 21.2 0.0 0.0003 21.1 0.0 1.0 1 0 0 1 1 1 1 RNase H zf-RVT PF13966.1 KLO03722.1 - 0.0049 17.1 0.7 0.0066 16.7 0.5 1.2 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase zf-C2H2_4 PF13894.1 KLO03724.1 - 0.037 14.3 0.5 0.22 11.9 0.1 2.2 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 KLO03724.1 - 0.12 12.5 0.2 1.1 9.4 0.1 2.3 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding DUF605 PF04652.11 KLO03725.1 - 0.085 12.2 9.6 0.11 11.8 6.6 1.1 1 0 0 1 1 1 0 Vta1 like KRAB PF01352.22 KLO03728.1 - 0.21 11.0 1.6 0.38 10.2 0.3 2.0 2 0 0 2 2 2 0 KRAB box SNF2_N PF00176.18 KLO03731.1 - 0.0095 14.7 0.0 0.012 14.4 0.0 1.3 1 1 0 1 1 1 1 SNF2 family N-terminal domain Aldo_ket_red PF00248.16 KLO03737.1 - 1.5e-08 33.7 0.0 1.8e-08 33.5 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family DUF4473 PF14747.1 KLO03737.1 - 0.017 15.3 0.0 0.053 13.7 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4473) Transposase_21 PF02992.9 KLO03738.1 - 0.02 13.9 0.2 0.033 13.2 0.0 1.5 2 0 0 2 2 2 0 Transposase family tnp2 zf-Di19 PF05605.7 KLO03740.1 - 0.0082 16.2 0.5 0.0082 16.2 0.3 1.9 2 0 0 2 2 2 1 Drought induced 19 protein (Di19), zinc-binding Med27 PF11571.3 KLO03740.1 - 1.7 8.8 6.8 0.15 12.1 0.2 2.5 2 1 1 3 3 3 0 Mediator complex subunit 27 Phage_integrase PF00589.17 KLO03742.1 - 9.1e-06 25.4 0.0 1.6e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 Phage integrase family DUF3701 PF12482.3 KLO03742.1 - 0.094 12.4 0.0 0.18 11.5 0.0 1.5 1 0 0 1 1 1 0 Phage integrase protein Spt5-NGN PF03439.8 KLO03743.1 - 5.3e-10 38.8 0.0 1.4e-09 37.5 0.0 1.7 1 1 0 1 1 1 1 Early transcription elongation factor of RNA pol II, NGN section CENP-B_dimeris PF09026.5 KLO03743.1 - 0.047 13.9 5.9 0.65 10.2 3.4 2.3 2 0 0 2 2 2 0 Centromere protein B dimerisation domain EBP PF05241.7 KLO03744.1 - 0.029 13.3 0.0 0.032 13.2 0.0 1.1 1 0 0 1 1 1 0 Emopamil binding protein Aldose_epim PF01263.15 KLO03746.1 - 4.3e-43 147.5 0.0 5e-43 147.3 0.0 1.0 1 0 0 1 1 1 1 Aldose 1-epimerase Gemini_mov PF01708.11 KLO03752.1 - 0.073 12.6 0.6 0.078 12.5 0.4 1.1 1 0 0 1 1 1 0 Geminivirus putative movement protein DUF3800 PF12686.2 KLO03753.1 - 0.0063 16.1 0.1 0.0075 15.9 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3800) DUF3843 PF12954.2 KLO03753.1 - 0.042 12.8 0.1 0.044 12.8 0.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3843) EnY2 PF10163.4 KLO03753.1 - 0.065 13.1 0.1 0.096 12.6 0.0 1.3 1 0 0 1 1 1 0 Transcription factor e(y)2 Patatin PF01734.17 KLO03755.1 - 4.1e-05 23.6 0.0 4.9e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 Patatin-like phospholipase Cwf_Cwc_15 PF04889.7 KLO03756.1 - 0.13 11.9 3.1 0.18 11.5 2.1 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein TFIIA PF03153.8 KLO03756.1 - 0.14 11.9 5.2 0.16 11.8 3.6 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Myc_N PF01056.13 KLO03756.1 - 1 8.4 5.5 1.2 8.2 3.8 1.1 1 0 0 1 1 1 0 Myc amino-terminal region Bd3614_N PF14442.1 KLO03756.1 - 3.3 7.6 7.3 6.2 6.7 5.1 1.5 1 0 0 1 1 1 0 Bd3614-like deaminase N-terminal TRAP_alpha PF03896.11 KLO03756.1 - 5.7 5.8 6.8 6.8 5.6 4.7 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit NOA36 PF06524.7 KLO03756.1 - 6.6 5.8 7.0 7.5 5.7 4.9 1.1 1 0 0 1 1 1 0 NOA36 protein DUF2457 PF10446.4 KLO03756.1 - 8.4 4.9 12.4 11 4.6 8.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Ssu72 PF04722.8 KLO03759.1 - 8e-05 22.0 0.1 0.00012 21.4 0.0 1.3 1 1 0 1 1 1 1 Ssu72-like protein N36 PF11438.3 KLO03759.1 - 0.097 12.1 0.3 0.18 11.3 0.2 1.4 1 0 0 1 1 1 0 36-mer N-terminal peptide of the N protein (N36) K-box PF01486.12 KLO03759.1 - 0.21 11.3 1.8 0.38 10.5 0.0 2.3 3 0 0 3 3 3 0 K-box region Kinesin-relat_1 PF12711.2 KLO03759.1 - 0.49 10.8 3.5 2.5 8.5 0.4 2.5 2 1 0 2 2 2 0 Kinesin motor F-box-like PF12937.2 KLO03761.1 - 0.00033 20.3 0.0 0.00073 19.2 0.0 1.6 1 1 0 1 1 1 1 F-box-like AAA PF00004.24 KLO03765.1 - 1.5e-44 151.3 0.0 2.2e-44 150.8 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_2 PF07724.9 KLO03765.1 - 2.2e-08 34.1 0.0 3.6e-08 33.5 0.0 1.3 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) CDC48_2 PF02933.12 KLO03765.1 - 2.7e-08 33.3 0.0 5.2e-08 32.4 0.0 1.5 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), domain 2 AAA_5 PF07728.9 KLO03765.1 - 7e-08 32.3 0.2 2.7e-07 30.3 0.1 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_33 PF13671.1 KLO03765.1 - 2.7e-07 30.5 0.0 6.4e-07 29.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain CDC48_N PF02359.13 KLO03765.1 - 5.1e-07 29.5 0.2 3.2e-06 26.9 0.1 2.3 2 0 0 2 2 2 1 Cell division protein 48 (CDC48), N-terminal domain RuvB_N PF05496.7 KLO03765.1 - 7.4e-07 28.4 0.0 2.1e-06 26.9 0.0 1.7 1 1 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 KLO03765.1 - 1.6e-05 25.0 0.1 0.0014 18.7 0.1 2.3 1 1 0 1 1 1 1 AAA domain TIP49 PF06068.8 KLO03765.1 - 0.00023 20.0 0.0 0.00033 19.5 0.0 1.2 1 0 0 1 1 1 1 TIP49 C-terminus AAA_17 PF13207.1 KLO03765.1 - 0.00026 21.7 0.0 0.00064 20.5 0.0 1.7 1 0 0 1 1 1 1 AAA domain KaiC PF06745.8 KLO03765.1 - 0.00027 20.1 0.6 0.33 10.0 0.1 2.2 1 1 1 2 2 2 2 KaiC AAA_25 PF13481.1 KLO03765.1 - 0.00037 19.9 0.4 0.13 11.6 0.0 2.4 1 1 1 2 2 2 1 AAA domain AAA_16 PF13191.1 KLO03765.1 - 0.00055 19.9 0.0 0.0025 17.8 0.0 1.9 1 1 0 1 1 1 1 AAA ATPase domain ResIII PF04851.10 KLO03765.1 - 0.00074 19.3 0.0 0.0011 18.7 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_14 PF13173.1 KLO03765.1 - 0.00083 19.2 0.0 0.0015 18.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 KLO03765.1 - 0.0021 17.1 0.0 0.0034 16.4 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin IstB_IS21 PF01695.12 KLO03765.1 - 0.0051 16.2 0.0 0.009 15.4 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein Mg_chelatase PF01078.16 KLO03765.1 - 0.0076 15.4 0.1 0.015 14.5 0.1 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.21 KLO03765.1 - 0.016 14.6 0.0 0.15 11.5 0.0 2.1 1 1 0 1 1 1 0 Sigma-54 interaction domain AAA_19 PF13245.1 KLO03765.1 - 0.018 14.7 0.7 0.042 13.5 0.1 1.9 2 0 0 2 2 2 0 Part of AAA domain Arch_ATPase PF01637.13 KLO03765.1 - 0.041 13.5 0.1 3.1 7.4 0.0 2.1 1 1 1 2 2 2 0 Archaeal ATPase AAA_18 PF13238.1 KLO03765.1 - 0.043 14.1 0.0 0.08 13.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.1 KLO03765.1 - 0.052 13.5 0.0 0.1 12.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain UFD1 PF03152.9 KLO03765.1 - 0.059 12.5 0.0 0.096 11.8 0.0 1.3 1 0 0 1 1 1 0 Ubiquitin fusion degradation protein UFD1 Sigma54_activ_2 PF14532.1 KLO03765.1 - 0.062 13.3 0.0 0.11 12.5 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain RNA_helicase PF00910.17 KLO03765.1 - 0.082 13.0 0.0 0.17 12.0 0.0 1.6 1 0 0 1 1 1 0 RNA helicase PhoH PF02562.11 KLO03765.1 - 0.083 12.1 0.1 0.18 10.9 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein AAA_11 PF13086.1 KLO03765.1 - 0.12 11.9 0.0 0.19 11.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain GATA PF00320.22 KLO03765.1 - 1.8 7.9 5.1 3.1 7.2 3.6 1.4 1 0 0 1 1 1 0 GATA zinc finger NB-ARC PF00931.17 KLO03766.1 - 1.2e-05 24.2 0.0 1.6e-05 23.8 0.0 1.4 1 1 0 1 1 1 1 NB-ARC domain AAA_22 PF13401.1 KLO03766.1 - 6.6e-05 23.0 0.0 8.3e-05 22.7 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 KLO03766.1 - 0.00013 21.9 0.0 0.00014 21.8 0.0 1.2 1 1 0 1 1 1 1 AAA ATPase domain AAA_17 PF13207.1 KLO03766.1 - 0.00013 22.7 0.1 0.00018 22.3 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA PF00004.24 KLO03766.1 - 0.00072 19.7 0.0 0.0015 18.7 0.0 1.5 1 1 1 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.1 KLO03766.1 - 0.00098 19.0 0.0 0.0012 18.7 0.0 1.3 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 KLO03766.1 - 0.0016 18.7 0.0 0.0019 18.4 0.0 1.3 1 1 0 1 1 1 1 AAA domain RNA_helicase PF00910.17 KLO03766.1 - 0.0034 17.5 0.0 0.0051 16.9 0.0 1.3 1 0 0 1 1 1 1 RNA helicase AAA_14 PF13173.1 KLO03766.1 - 0.0086 15.9 0.0 0.0093 15.8 0.0 1.3 1 1 0 1 1 1 1 AAA domain Arch_ATPase PF01637.13 KLO03766.1 - 0.0097 15.6 0.0 0.011 15.4 0.0 1.1 1 0 0 1 1 1 1 Archaeal ATPase IstB_IS21 PF01695.12 KLO03766.1 - 0.01 15.2 0.0 0.014 14.8 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein ABC_tran PF00005.22 KLO03766.1 - 0.01 16.1 0.0 0.036 14.3 0.0 1.7 1 1 0 2 2 2 0 ABC transporter DUF258 PF03193.11 KLO03766.1 - 0.011 14.8 0.0 0.011 14.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function, DUF258 NACHT PF05729.7 KLO03766.1 - 0.015 14.9 0.0 0.017 14.8 0.0 1.3 1 0 0 1 1 1 0 NACHT domain AAA_28 PF13521.1 KLO03766.1 - 0.016 15.1 0.0 0.023 14.6 0.0 1.4 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.1 KLO03766.1 - 0.017 14.5 0.0 0.025 13.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.1 KLO03766.1 - 0.022 14.5 0.0 0.041 13.6 0.0 1.4 1 0 0 1 1 1 0 Part of AAA domain AAA_10 PF12846.2 KLO03766.1 - 0.024 14.1 0.0 0.04 13.3 0.0 1.4 2 0 0 2 2 2 0 AAA-like domain MMR_HSR1 PF01926.18 KLO03766.1 - 0.027 14.4 0.0 0.031 14.2 0.0 1.3 1 1 0 1 1 1 0 50S ribosome-binding GTPase MobB PF03205.9 KLO03766.1 - 0.05 13.3 0.0 0.076 12.7 0.0 1.3 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B RNA12 PF10443.4 KLO03766.1 - 0.053 12.0 0.0 0.06 11.8 0.0 1.1 1 0 0 1 1 1 0 RNA12 protein AAA_5 PF07728.9 KLO03766.1 - 0.077 12.7 0.0 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) RuvB_N PF05496.7 KLO03766.1 - 0.086 11.8 0.0 0.11 11.5 0.0 1.2 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus AAA_24 PF13479.1 KLO03766.1 - 0.089 12.3 0.0 0.12 11.9 0.0 1.2 1 0 0 1 1 1 0 AAA domain PPV_E1_C PF00519.12 KLO03766.1 - 0.1 11.2 0.0 0.13 10.8 0.0 1.1 1 0 0 1 1 1 0 Papillomavirus helicase Rad17 PF03215.10 KLO03766.1 - 0.1 11.2 0.0 0.13 10.9 0.0 1.1 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein NTPase_1 PF03266.10 KLO03766.1 - 0.11 12.1 0.0 0.16 11.6 0.0 1.3 1 0 0 1 1 1 0 NTPase AAA_29 PF13555.1 KLO03766.1 - 0.11 12.0 0.0 0.18 11.3 0.0 1.3 1 0 0 1 1 1 0 P-loop containing region of AAA domain HPIP PF15226.1 KLO03780.1 - 0.13 12.2 0.7 0.94 9.5 0.1 2.0 1 1 0 2 2 2 0 HCF-1 beta-propeller-interacting protein family DUF3505 PF12013.3 KLO03783.1 - 0.0026 17.9 0.2 0.0026 17.9 0.2 2.3 3 1 0 3 3 3 1 Protein of unknown function (DUF3505) DUF3270 PF11674.3 KLO03788.1 - 5.4 7.1 7.5 0.54 10.3 1.8 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3270) DEAD PF00270.24 KLO03791.1 - 2.6e-07 30.3 0.0 1e-06 28.3 0.0 1.9 1 1 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.10 KLO03791.1 - 0.026 14.3 0.0 0.039 13.8 0.0 1.2 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit T4SS-DNA_transf PF02534.9 KLO03791.1 - 0.071 11.6 0.0 0.099 11.2 0.0 1.1 1 0 0 1 1 1 0 Type IV secretory system Conjugative DNA transfer DUF3080 PF11279.3 KLO03795.1 - 0.32 10.1 2.7 0.79 8.8 1.8 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF3080) gag_pre-integrs PF13976.1 KLO03799.1 - 2.1e-05 24.0 0.0 2.7e-05 23.7 0.0 1.2 1 0 0 1 1 1 1 GAG-pre-integrase domain Aspzincin_M35 PF14521.1 KLO03800.1 - 0.097 13.1 0.4 0.22 12.0 0.3 1.6 1 0 0 1 1 1 0 Lysine-specific metallo-endopeptidase Peptidase_M50 PF02163.17 KLO03801.1 - 1.7e-05 23.8 1.6 0.0036 16.2 1.3 2.8 2 1 0 2 2 2 1 Peptidase family M50 Lipoprotein_7 PF01540.11 KLO03803.1 - 0.0018 17.4 5.5 0.003 16.6 3.8 1.2 1 0 0 1 1 1 1 Adhesin lipoprotein MbeD_MobD PF04899.7 KLO03803.1 - 0.011 15.5 0.6 0.035 13.9 0.4 1.9 1 0 0 1 1 1 0 MbeD/MobD like DUF342 PF03961.8 KLO03803.1 - 0.35 9.2 6.8 0.56 8.5 4.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF342) DUF2120 PF09893.4 KLO03803.1 - 0.59 10.0 3.9 1.3 8.9 2.7 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2120) Orbi_VP5 PF00901.12 KLO03803.1 - 0.77 7.8 8.4 1.2 7.2 5.8 1.2 1 0 0 1 1 1 0 Orbivirus outer capsid protein VP5 IncA PF04156.9 KLO03803.1 - 2.4 7.7 11.9 0.29 10.7 4.8 2.0 3 0 0 3 3 3 0 IncA protein DUF972 PF06156.8 KLO03803.1 - 6.1 7.2 8.5 5.3 7.4 1.2 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF972) Laminin_II PF06009.7 KLO03803.1 - 6.8 6.4 13.8 0.9 9.2 1.1 2.4 2 1 1 3 3 3 0 Laminin Domain II GPI-anchored PF10342.4 KLO03806.1 - 2.3e-05 24.7 0.1 9.7e-05 22.7 0.1 1.8 1 1 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family DUF4448 PF14610.1 KLO03806.1 - 0.14 11.6 0.0 0.18 11.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) Ribonuc_red_sm PF00268.16 KLO03816.1 - 6.5e-113 376.4 2.9 8.2e-113 376.0 2.0 1.0 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain DUF4597 PF15366.1 KLO03818.1 - 0.58 9.7 6.5 2.6 7.6 0.7 3.2 2 1 0 2 2 2 0 Domain of unknown function (DUF4597) DEAD PF00270.24 KLO03820.1 - 7.3e-08 32.0 0.0 9.3e-08 31.7 0.0 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.10 KLO03820.1 - 2.4e-05 24.2 0.0 8.1e-05 22.5 0.0 1.7 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit T4SS-DNA_transf PF02534.9 KLO03820.1 - 0.031 12.8 0.0 0.043 12.4 0.0 1.1 1 0 0 1 1 1 0 Type IV secretory system Conjugative DNA transfer DUF853 PF05872.7 KLO03820.1 - 0.053 11.8 0.0 0.058 11.7 0.0 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) AAA_22 PF13401.1 KLO03820.1 - 0.1 12.7 0.4 1.3 9.1 0.3 2.1 1 1 0 1 1 1 0 AAA domain HTH_Tnp_Tc5 PF03221.11 KLO03823.1 - 2.7e-12 46.3 0.0 4.5e-12 45.6 0.0 1.4 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain HTH_38 PF13936.1 KLO03823.1 - 0.0079 15.7 0.0 0.018 14.5 0.0 1.7 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_23 PF13384.1 KLO03823.1 - 0.066 12.8 0.0 0.32 10.6 0.0 2.1 2 0 0 2 2 2 0 Homeodomain-like domain DUF2535 PF10751.4 KLO03827.1 - 0.04 14.0 0.0 0.17 12.0 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2535) Patatin PF01734.17 KLO03828.1 - 2.5e-09 37.3 1.5 2.7e-09 37.2 1.1 1.0 1 0 0 1 1 1 1 Patatin-like phospholipase Patatin PF01734.17 KLO03829.1 - 1.5e-09 38.0 0.2 2.1e-09 37.5 0.1 1.4 1 1 0 1 1 1 1 Patatin-like phospholipase 1-cysPrx_C PF10417.4 KLO03831.1 - 0.016 14.8 0.0 0.045 13.4 0.0 1.8 1 0 0 1 1 1 0 C-terminal domain of 1-Cys peroxiredoxin MazG PF03819.12 KLO03831.1 - 0.051 13.5 2.1 0.091 12.7 0.1 2.2 2 0 0 2 2 2 0 MazG nucleotide pyrophosphohydrolase domain Sec16 PF12932.2 KLO03831.1 - 0.23 11.4 1.7 0.55 10.2 1.2 1.7 1 1 0 1 1 1 0 Vesicle coat trafficking protein Sec16 mid-region Patatin PF01734.17 KLO03832.1 - 2.5e-09 37.3 0.9 2.7e-09 37.2 0.6 1.0 1 0 0 1 1 1 1 Patatin-like phospholipase Patatin PF01734.17 KLO03833.1 - 1.7e-10 41.1 0.2 1.5e-09 38.1 0.1 2.0 1 1 0 1 1 1 1 Patatin-like phospholipase DUF1033 PF06279.6 KLO03837.1 - 0.095 12.5 0.0 0.18 11.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1033) Nha1_C PF08619.5 KLO03837.1 - 0.43 9.8 3.9 0.65 9.2 2.7 1.4 1 1 0 1 1 1 0 Alkali metal cation/H+ antiporter Nha1 C terminus TraC_F_IV PF11130.3 KLO03840.1 - 0.038 13.4 0.2 0.26 10.6 0.0 2.1 1 1 1 2 2 2 0 F pilus assembly Type-IV secretion system for plasmid transfer LRR_4 PF12799.2 KLO03841.1 - 0.034 13.7 0.1 0.12 11.9 0.0 2.0 2 0 0 2 2 2 0 Leucine Rich repeats (2 copies) Sua5_yciO_yrdC PF01300.13 KLO03843.1 - 0.043 13.0 0.7 0.082 12.1 0.4 1.4 1 1 0 1 1 1 0 Telomere recombination Med13_C PF06333.7 KLO03843.1 - 1.2 7.6 5.9 1.6 7.1 4.1 1.1 1 0 0 1 1 1 0 Mediator complex subunit 13 C-terminal Ofd1_CTDD PF10637.4 KLO03844.1 - 5.7e-18 65.0 0.1 6.4e-13 48.4 0.0 2.7 2 1 0 2 2 2 2 Oxoglutarate and iron-dependent oxygenase degradation C-term 2OG-FeII_Oxy_3 PF13640.1 KLO03844.1 - 6.3e-15 55.5 0.0 1.2e-14 54.5 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Ribosomal_L18e PF00828.14 KLO03847.1 - 1.5e-12 47.9 0.0 2.6e-12 47.2 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L18e/L15 MAGE PF01454.14 KLO03854.1 - 0.0069 15.7 0.0 0.0085 15.4 0.0 1.2 1 0 0 1 1 1 1 MAGE family Nucleoporin_FG PF13634.1 KLO03855.1 - 5.4 7.2 12.5 10 6.3 8.5 1.5 1 1 0 1 1 1 0 Nucleoporin FG repeat region p450 PF00067.17 KLO03856.1 - 0.0067 15.0 0.0 0.0076 14.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 LLC1 PF14945.1 KLO03858.1 - 0.091 13.0 0.9 0.15 12.3 0.5 1.5 1 1 0 1 1 1 0 Normal lung function maintenance, Low in Lung Cancer 1 protein UBN2_3 PF14244.1 KLO03861.1 - 3.1e-06 26.8 0.0 0.043 13.3 0.0 2.4 2 0 0 2 2 2 2 gag-polypeptide of LTR copia-type DUF4219 PF13961.1 KLO03861.1 - 1.5e-05 24.2 0.1 3.4e-05 23.1 0.1 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4219) UBN2_2 PF14227.1 KLO03861.1 - 3.2e-05 23.4 0.1 6.8e-05 22.4 0.1 1.5 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type Clathrin_bdg PF15045.1 KLO03862.1 - 0.11 12.0 0.0 0.28 10.6 0.0 1.6 2 0 0 2 2 2 0 Clathrin-binding box of Aftiphilin, vesicle trafficking HTH_Tnp_Tc5 PF03221.11 KLO03863.1 - 4.2e-11 42.4 0.0 1e-10 41.2 0.0 1.7 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain CENP-B_N PF04218.8 KLO03863.1 - 0.0039 16.5 0.7 0.029 13.7 0.2 2.2 2 0 0 2 2 2 1 CENP-B N-terminal DNA-binding domain MarR PF01047.17 KLO03863.1 - 0.053 13.2 0.2 0.21 11.3 0.0 2.0 2 0 0 2 2 2 0 MarR family HTH_Tnp_4 PF13613.1 KLO03863.1 - 0.12 11.9 0.0 0.24 10.9 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix of DDE superfamily endonuclease 2-ph_phosp PF04029.9 KLO03873.1 - 0.078 11.9 2.0 0.079 11.9 1.4 1.2 1 0 0 1 1 1 0 2-phosphosulpholactate phosphatase Bac_export_3 PF01313.14 KLO03873.1 - 0.63 9.7 2.8 2.1 8.0 2.0 1.8 1 1 0 1 1 1 0 Bacterial export proteins, family 3 PC_rep PF01851.17 KLO03874.1 - 6.1e-31 104.9 15.4 1.9e-07 30.9 0.1 8.4 9 0 0 9 9 9 6 Proteasome/cyclosome repeat HEAT_2 PF13646.1 KLO03874.1 - 2e-12 47.2 0.8 0.00022 21.4 0.1 3.6 1 1 3 4 4 4 4 HEAT repeats HEAT PF02985.17 KLO03874.1 - 0.00046 20.0 0.4 0.53 10.4 0.1 3.2 3 0 0 3 3 3 2 HEAT repeat HEAT_EZ PF13513.1 KLO03874.1 - 0.0013 19.1 0.1 2.5 8.6 0.0 4.1 3 0 0 3 3 3 1 HEAT-like repeat CTK3_C PF12350.3 KLO03878.1 - 4.6e-16 58.6 12.0 1.6e-15 56.8 8.3 1.8 1 1 0 1 1 1 1 CTD kinase subunit gamma CTK3 C-terminus CTK3_C PF12350.3 KLO03890.1 - 9.2e-15 54.4 15.1 8.1e-14 51.4 10.5 2.1 1 1 0 1 1 1 1 CTD kinase subunit gamma CTK3 C-terminus CTK3 PF12243.3 KLO03890.1 - 7.1e-08 32.1 0.0 1e-07 31.6 0.0 1.3 1 0 0 1 1 1 1 CTD kinase subunit gamma CTK3 Helitron_like_N PF14214.1 KLO03892.1 - 0.00039 20.1 0.0 0.00047 19.9 0.0 1.2 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus Gemini_AL1 PF00799.15 KLO03892.1 - 0.18 11.6 0.7 1.2 9.0 0.1 2.3 1 1 2 3 3 3 0 Geminivirus Rep catalytic domain RNase_T PF00929.19 KLO03896.1 - 3.3e-11 43.7 0.0 5.7e-11 42.9 0.0 1.4 1 0 0 1 1 1 1 Exonuclease RNase_H_2 PF13482.1 KLO03896.1 - 4.2e-06 26.6 0.2 0.00011 22.0 0.2 2.3 1 1 0 1 1 1 1 RNase_H superfamily DNA_pol_B_exo1 PF03104.14 KLO03896.1 - 0.026 13.3 0.6 0.046 12.5 0.4 1.4 1 1 0 1 1 1 0 DNA polymerase family B, exonuclease domain Spt5-NGN PF03439.8 KLO03897.1 - 7.2e-13 48.0 0.0 4.4e-12 45.5 0.0 1.9 2 0 0 2 2 2 1 Early transcription elongation factor of RNA pol II, NGN section Daxx PF03344.10 KLO03897.1 - 2.1 6.6 6.1 2.6 6.4 4.3 1.0 1 0 0 1 1 1 0 Daxx Family DUF2457 PF10446.4 KLO03897.1 - 2.2 6.9 10.7 2.7 6.5 7.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) UPF0158 PF03682.8 KLO03899.1 - 0.11 12.1 0.0 0.16 11.5 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0158) UBN2_2 PF14227.1 KLO03903.1 - 0.0021 17.5 0.0 0.0054 16.2 0.0 1.6 1 1 0 1 1 1 1 gag-polypeptide of LTR copia-type UBN2 PF14223.1 KLO03903.1 - 0.084 12.6 0.1 0.51 10.1 0.0 2.0 1 1 0 1 1 1 0 gag-polypeptide of LTR copia-type DUF755 PF05501.6 KLO03903.1 - 0.13 12.3 6.1 0.19 11.8 4.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF755) SR-25 PF10500.4 KLO03903.1 - 0.17 11.2 13.1 0.26 10.7 9.0 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein zf-CCHC_4 PF14392.1 KLO03903.1 - 0.18 11.5 1.5 0.66 9.6 0.9 2.0 2 0 0 2 2 2 0 Zinc knuckle Ribonuc_red_lgC PF02867.10 KLO03909.1 - 6.5e-08 31.5 0.5 6.5e-08 31.5 0.3 1.7 2 0 0 2 2 2 1 Ribonucleotide reductase, barrel domain G-gamma PF00631.17 KLO03909.1 - 0.079 12.7 0.0 0.17 11.6 0.0 1.5 1 0 0 1 1 1 0 GGL domain RVT_1 PF00078.22 KLO03912.1 - 0.003 16.9 0.1 0.003 16.9 0.0 1.9 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Rsc14 PF08586.5 KLO03912.1 - 0.013 15.9 0.3 0.013 15.9 0.2 2.1 2 0 0 2 2 2 0 RSC complex, Rsc14/Ldb7 subunit Nuc_deoxyrib_tr PF05014.10 KLO03912.1 - 0.076 12.8 0.0 0.16 11.8 0.0 1.5 1 0 0 1 1 1 0 Nucleoside 2-deoxyribosyltransferase Pneumo_att_G PF05539.6 KLO03912.1 - 0.51 9.6 2.1 0.75 9.1 1.5 1.2 1 0 0 1 1 1 0 Pneumovirinae attachment membrane glycoprotein G PEP-utilisers_N PF05524.8 KLO03918.1 - 0.038 13.8 2.1 0.068 12.9 0.3 2.2 2 0 0 2 2 2 0 PEP-utilising enzyme, N-terminal F-box PF00646.28 KLO03919.1 - 0.00019 21.0 0.0 0.00028 20.4 0.0 1.3 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 KLO03919.1 - 0.052 13.2 0.0 0.072 12.8 0.0 1.3 1 0 0 1 1 1 0 F-box-like TMEM191C PF15194.1 KLO03921.1 - 0.076 12.8 0.0 0.095 12.5 0.0 1.1 1 0 0 1 1 1 0 TMEM191C family WD40 PF00400.27 KLO03924.1 - 1.6e-16 59.4 4.1 1.7e-12 46.7 0.1 2.7 3 0 0 3 3 3 2 WD domain, G-beta repeat Nup160 PF11715.3 KLO03924.1 - 0.0092 14.1 1.1 0.71 7.9 0.1 2.1 1 1 1 2 2 2 2 Nucleoporin Nup120/160 RVT_1 PF00078.22 KLO03925.1 - 0.00019 20.8 0.1 0.00032 20.1 0.1 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) HMG_box_2 PF09011.5 KLO03926.1 - 8e-08 32.5 0.0 1.5e-07 31.6 0.0 1.4 1 0 0 1 1 1 1 HMG-box domain HMG_box PF00505.14 KLO03926.1 - 4.1e-05 23.7 0.0 7.8e-05 22.8 0.0 1.5 1 0 0 1 1 1 1 HMG (high mobility group) box IZUMO PF15005.1 KLO03926.1 - 0.091 12.7 0.0 0.15 12.1 0.0 1.3 1 0 0 1 1 1 0 Izumo sperm-egg fusion Hexapep PF00132.19 KLO03928.1 - 0.015 14.7 0.0 0.02 14.3 0.0 1.2 1 0 0 1 1 1 0 Bacterial transferase hexapeptide (six repeats) WD40 PF00400.27 KLO03932.1 - 2.3e-13 49.4 5.9 3.6e-09 36.1 0.0 3.4 3 0 0 3 3 3 3 WD domain, G-beta repeat DUF4221 PF13970.1 KLO03932.1 - 0.076 12.3 0.0 0.088 12.1 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4221) TFIIIC_delta PF12657.2 KLO03932.1 - 0.11 12.1 0.1 0.17 11.6 0.0 1.3 1 0 0 1 1 1 0 Transcription factor IIIC subunit delta N-term Asp_protease_2 PF13650.1 KLO03938.1 - 8.9e-07 29.3 0.0 1.5e-06 28.5 0.0 1.4 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.6 KLO03938.1 - 3.2e-06 27.1 0.0 4.6e-06 26.5 0.0 1.2 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.1 KLO03938.1 - 5.7e-06 26.0 0.0 1.2e-05 25.0 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.5 KLO03938.1 - 2.3e-05 23.9 0.0 3.5e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.15 KLO03938.1 - 0.037 13.9 0.0 0.066 13.1 0.0 1.5 1 0 0 1 1 1 0 Retroviral aspartyl protease Phe_tRNA-synt_N PF02912.13 KLO03940.1 - 0.054 13.2 0.1 0.11 12.1 0.1 1.5 1 0 0 1 1 1 0 Aminoacyl tRNA synthetase class II, N-terminal domain Alpha-amylase PF00128.19 KLO03941.1 - 2e-70 237.6 3.7 2.6e-70 237.3 2.5 1.1 1 0 0 1 1 1 1 Alpha amylase, catalytic domain hDGE_amylase PF14701.1 KLO03941.1 - 5.7e-05 22.1 0.1 8.2e-05 21.6 0.0 1.1 1 0 0 1 1 1 1 glucanotransferase domain of human glycogen debranching enzyme PIF1 PF05970.9 KLO03942.1 - 1.2e-09 37.5 0.7 3.5e-07 29.5 0.1 2.4 1 1 1 2 2 2 2 PIF1-like helicase Asp_protease_2 PF13650.1 KLO03949.1 - 1.2e-07 32.0 0.0 3.4e-07 30.6 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.6 KLO03949.1 - 3.4e-06 27.0 0.1 9.3e-06 25.6 0.0 1.7 2 0 0 2 2 2 1 Retroviral aspartyl protease gag-asp_proteas PF13975.1 KLO03949.1 - 4.2e-06 26.4 0.0 8.4e-06 25.5 0.0 1.4 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease PF09668.5 KLO03949.1 - 7.4e-05 22.3 0.0 0.00013 21.5 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.15 KLO03949.1 - 0.048 13.5 0.0 0.094 12.6 0.0 1.5 1 0 0 1 1 1 0 Retroviral aspartyl protease ocr PF08684.5 KLO03949.1 - 0.1 12.6 0.0 0.24 11.4 0.0 1.6 1 0 0 1 1 1 0 DNA mimic ocr HMG_box_2 PF09011.5 KLO03950.1 - 5.6e-05 23.4 0.2 9.4e-05 22.7 0.1 1.3 1 0 0 1 1 1 1 HMG-box domain HMG_box PF00505.14 KLO03950.1 - 0.00038 20.6 0.1 0.00075 19.7 0.1 1.5 1 0 0 1 1 1 1 HMG (high mobility group) box WD40 PF00400.27 KLO03953.1 - 2.5e-18 65.1 0.6 1.3e-13 50.2 0.1 2.0 2 0 0 2 2 2 2 WD domain, G-beta repeat HbrB PF08539.6 KLO03956.1 - 0.0013 18.5 0.0 0.0023 17.7 0.0 1.4 1 0 0 1 1 1 1 HbrB-like BAH PF01426.13 KLO03960.1 - 0.00043 20.0 3.6 0.0015 18.3 2.5 2.0 1 1 0 1 1 1 1 BAH domain PHD PF00628.24 KLO03960.1 - 0.012 15.2 2.9 0.053 13.2 0.3 2.4 2 0 0 2 2 2 0 PHD-finger Microtub_assoc PF07989.6 KLO03961.1 - 0.046 13.5 0.4 0.21 11.4 0.1 2.2 2 0 0 2 2 2 0 Microtubule associated Complex1_LYR PF05347.10 KLO03963.1 - 1.7e-10 40.5 3.2 2.1e-10 40.2 2.2 1.1 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 KLO03963.1 - 1.1e-09 38.2 2.6 1.4e-09 37.9 1.8 1.1 1 0 0 1 1 1 1 Complex1_LYR-like LuxS PF02664.10 KLO03963.1 - 0.14 11.7 0.0 0.16 11.5 0.0 1.1 1 0 0 1 1 1 0 S-Ribosylhomocysteinase (LuxS) PQQ_2 PF13360.1 KLO03964.1 - 0.14 11.5 0.0 0.58 9.5 0.0 1.8 1 1 0 1 1 1 0 PQQ-like domain Mago-bind PF09282.5 KLO03965.1 - 0.28 10.7 8.1 0.42 10.2 0.4 3.6 4 0 0 4 4 4 0 Mago binding Aldo_ket_red PF00248.16 KLO03966.1 - 1.4e-30 106.0 0.0 2.9e-30 105.0 0.0 1.4 1 1 0 1 1 1 1 Aldo/keto reductase family Dscam_C PF12355.3 KLO03966.1 - 0.033 14.4 0.7 0.057 13.6 0.5 1.4 1 0 0 1 1 1 0 Down syndrome cell adhesion molecule C terminal HTH_28 PF13518.1 KLO03966.1 - 0.046 13.7 0.0 0.093 12.7 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_23 PF13384.1 KLO03966.1 - 0.061 13.0 0.0 0.13 11.9 0.0 1.5 1 0 0 1 1 1 0 Homeodomain-like domain Mito_fiss_reg PF05308.6 KLO03966.1 - 0.19 11.0 0.7 0.26 10.6 0.5 1.1 1 0 0 1 1 1 0 Mitochondrial fission regulator SbmA_BacA PF05992.7 KLO03966.1 - 0.19 10.8 0.0 0.26 10.4 0.0 1.1 1 0 0 1 1 1 0 SbmA/BacA-like family Nop14 PF04147.7 KLO03972.1 - 5.2 4.8 14.8 7 4.4 10.3 1.2 1 0 0 1 1 1 0 Nop14-like family SBP_bac_1 PF01547.20 KLO03974.1 - 0.086 12.5 0.0 0.12 12.1 0.0 1.3 1 0 0 1 1 1 0 Bacterial extracellular solute-binding protein gag_pre-integrs PF13976.1 KLO03975.1 - 2.7e-08 33.3 0.0 3.8e-08 32.8 0.0 1.2 1 0 0 1 1 1 1 GAG-pre-integrase domain rve PF00665.21 KLO03975.1 - 0.016 15.3 0.1 0.52 10.4 0.0 2.0 1 1 1 2 2 2 0 Integrase core domain DUF3505 PF12013.3 KLO03978.1 - 9.6e-08 32.2 0.6 6e-07 29.6 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF3505) DM PF00751.13 KLO03978.1 - 0.0063 16.0 3.2 0.0063 16.0 0.6 2.2 2 0 0 2 2 2 1 DM DNA binding domain zf-C2H2_4 PF13894.1 KLO03978.1 - 0.48 10.8 21.6 6.1 7.4 0.1 4.6 4 0 0 4 4 4 0 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 KLO03978.1 - 1.2 9.3 9.5 25 5.1 0.0 4.5 4 0 0 4 4 4 0 Zinc-finger double-stranded RNA-binding Mak16 PF04874.9 KLO03979.1 - 0.076 13.1 0.3 39 4.4 0.0 3.4 3 0 0 3 3 3 0 Mak16 protein C-terminal region APC_crr PF05923.7 KLO03981.1 - 0.0075 15.8 4.3 0.032 13.8 3.0 2.2 1 0 0 1 1 1 1 APC cysteine-rich region F-box PF00646.28 KLO03982.1 - 0.00086 18.8 0.0 0.0013 18.3 0.0 1.3 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 KLO03982.1 - 0.091 12.5 0.0 0.14 11.9 0.0 1.3 1 0 0 1 1 1 0 F-box-like CAAP1 PF15335.1 KLO03983.1 - 0.033 14.3 0.1 0.063 13.4 0.1 1.5 1 0 0 1 1 1 0 Caspase activity and apoptosis inhibitor 1 CTK3 PF12243.3 KLO03986.1 - 1.3e-26 92.8 0.1 1.4e-26 92.7 0.0 1.0 1 0 0 1 1 1 1 CTD kinase subunit gamma CTK3 CENP-B_N PF04218.8 KLO03989.1 - 1.5e-05 24.2 0.0 2.7e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 CENP-B N-terminal DNA-binding domain HTH_7 PF02796.10 KLO03989.1 - 0.0026 17.5 0.0 0.005 16.6 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain of resolvase HTH_23 PF13384.1 KLO03989.1 - 0.014 15.0 0.0 0.026 14.1 0.0 1.5 1 0 0 1 1 1 0 Homeodomain-like domain HTH_38 PF13936.1 KLO03989.1 - 0.026 14.0 0.0 0.06 12.9 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_psq PF05225.11 KLO03989.1 - 0.055 13.0 0.0 0.1 12.1 0.0 1.5 1 0 0 1 1 1 0 helix-turn-helix, Psq domain Mga PF05043.8 KLO03989.1 - 0.062 13.5 0.0 0.14 12.4 0.0 1.6 1 0 0 1 1 1 0 Mga helix-turn-helix domain HTH_32 PF13565.1 KLO03989.1 - 0.071 13.9 0.1 0.14 12.9 0.0 1.5 1 0 0 1 1 1 0 Homeodomain-like domain HTH_28 PF13518.1 KLO03989.1 - 0.11 12.5 0.1 0.26 11.3 0.0 1.7 1 1 0 1 1 1 0 Helix-turn-helix domain HTH_11 PF08279.7 KLO03989.1 - 0.14 11.8 0.0 0.27 10.8 0.0 1.4 1 0 0 1 1 1 0 HTH domain Skp1 PF01466.14 KLO03990.1 - 4.1e-20 71.5 0.0 7e-20 70.8 0.0 1.4 1 0 0 1 1 1 1 Skp1 family, dimerisation domain Skp1_POZ PF03931.10 KLO03990.1 - 2.7e-12 46.5 0.1 9e-12 44.9 0.0 1.9 2 0 0 2 2 2 1 Skp1 family, tetramerisation domain APP_N PF02177.11 KLO03990.1 - 0.12 12.3 0.1 0.25 11.3 0.0 1.6 2 0 0 2 2 2 0 Amyloid A4 N-terminal heparin-binding T5orf172 PF10544.4 KLO03991.1 - 0.11 12.9 0.1 0.18 12.2 0.1 1.5 1 1 0 1 1 1 0 T5orf172 domain MutS_II PF05188.12 KLO03991.1 - 0.12 12.3 0.3 0.25 11.4 0.0 1.6 2 0 0 2 2 2 0 MutS domain II Transposase_24 PF03004.9 KLO03993.1 - 0.0065 16.3 0.5 0.022 14.6 0.4 1.9 1 0 0 1 1 1 1 Plant transposase (Ptta/En/Spm family) GrpE PF01025.14 KLO03995.1 - 0.061 12.8 0.0 0.067 12.7 0.0 1.0 1 0 0 1 1 1 0 GrpE Transposase_21 PF02992.9 KLO03996.1 - 8.3e-10 38.1 0.0 1e-09 37.8 0.0 1.1 1 0 0 1 1 1 1 Transposase family tnp2 DUF4218 PF13960.1 KLO03997.1 - 3.9e-06 26.3 0.3 5.7e-06 25.7 0.2 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4218) Glucodextran_B PF09136.5 KLO03998.1 - 0.049 13.7 0.0 0.066 13.3 0.0 1.2 1 0 0 1 1 1 0 Glucodextranase, domain B TC1 PF15063.1 KLO03998.1 - 0.057 12.9 0.0 0.11 12.0 0.0 1.4 1 0 0 1 1 1 0 Thyroid cancer protein 1 Skp1 PF01466.14 KLO03999.1 - 3.3e-20 71.8 0.0 5.2e-20 71.2 0.0 1.3 1 0 0 1 1 1 1 Skp1 family, dimerisation domain Skp1_POZ PF03931.10 KLO03999.1 - 1.3e-12 47.6 0.1 2.1e-12 46.9 0.1 1.3 1 0 0 1 1 1 1 Skp1 family, tetramerisation domain BTB PF00651.26 KLO03999.1 - 0.047 13.6 0.3 0.41 10.6 0.2 2.1 1 1 0 1 1 1 0 BTB/POZ domain Mesd PF10185.4 KLO04000.1 - 0.042 13.5 0.2 0.099 12.3 0.0 1.6 1 1 0 1 1 1 0 Chaperone for wingless signalling and trafficking of LDL receptor Transposase_21 PF02992.9 KLO04001.1 - 2.7e-10 39.7 0.0 4.1e-10 39.1 0.0 1.3 1 0 0 1 1 1 1 Transposase family tnp2 DUF4218 PF13960.1 KLO04001.1 - 0.0067 15.8 0.0 0.013 14.9 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4218) Asp_protease_2 PF13650.1 KLO04004.1 - 5.9e-06 26.6 0.0 1.4e-05 25.5 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.1 KLO04004.1 - 0.031 14.0 0.0 0.065 13.0 0.0 1.4 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease CReP_N PF10472.4 KLO04004.1 - 0.041 12.5 0.5 0.08 11.6 0.0 1.6 2 0 0 2 2 2 0 eIF2-alpha phosphatase phosphorylation constitutive repressor DDE_1 PF03184.14 KLO04005.1 - 4.4e-46 156.7 0.0 6.2e-46 156.2 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.11 KLO04005.1 - 2.2e-08 33.8 0.0 6.9e-08 32.1 0.0 1.9 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain HdeA PF06411.6 KLO04009.1 - 0.076 12.9 0.2 0.29 11.1 0.0 2.0 2 0 0 2 2 2 0 HdeA/HdeB family PulS_OutS PF09691.5 KLO04010.1 - 0.032 14.2 0.6 0.11 12.4 0.0 2.1 1 1 0 2 2 2 0 Bacterial chaperone lipoprotein (PulS_OutS) DUF1249 PF06853.7 KLO04014.1 - 0.02 14.5 0.1 0.034 13.7 0.1 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1249) Retrotrans_gag PF03732.12 KLO04014.1 - 0.13 12.3 1.8 0.18 11.8 0.4 1.8 2 0 0 2 2 2 0 Retrotransposon gag protein PAT1 PF09770.4 KLO04015.1 - 0.61 8.2 4.2 0.75 7.9 2.9 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DDE_3 PF13358.1 KLO04016.1 - 1.8e-08 34.2 0.0 3.6e-08 33.2 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_23 PF13384.1 KLO04016.1 - 9.9e-06 25.0 0.1 3.8e-05 23.1 0.0 2.0 2 0 0 2 2 2 1 Homeodomain-like domain HTH_33 PF13592.1 KLO04016.1 - 3.7e-05 23.1 0.0 7.2e-05 22.2 0.0 1.5 1 0 0 1 1 1 1 Winged helix-turn helix HTH_Tnp_1 PF01527.15 KLO04016.1 - 0.00063 19.6 0.0 0.0016 18.3 0.0 1.7 1 0 0 1 1 1 1 Transposase HTH_29 PF13551.1 KLO04016.1 - 0.0015 18.6 0.0 0.24 11.5 0.0 2.8 2 1 0 2 2 2 1 Winged helix-turn helix HTH_32 PF13565.1 KLO04016.1 - 0.0015 19.2 0.1 0.0091 16.7 0.1 2.1 1 1 1 2 2 2 1 Homeodomain-like domain HTH_26 PF13443.1 KLO04016.1 - 0.062 13.5 0.0 6.9 6.9 0.0 2.3 2 0 0 2 2 2 0 Cro/C1-type HTH DNA-binding domain HTH_7 PF02796.10 KLO04016.1 - 0.12 12.2 0.0 0.29 11.0 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain of resolvase RVP PF00077.15 KLO04018.1 - 0.002 17.9 0.1 0.003 17.4 0.1 1.3 1 1 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.1 KLO04018.1 - 0.026 15.0 0.0 0.034 14.6 0.0 1.1 1 0 0 1 1 1 0 Aspartyl protease Spt5_N PF11942.3 KLO04019.1 - 1.5 9.5 8.7 3.3 8.3 6.0 1.5 1 0 0 1 1 1 0 Spt5 transcription elongation factor, acidic N-terminal Glyco_hydro_16 PF00722.16 KLO04028.1 - 2.3e-13 49.8 0.0 3.7e-13 49.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 EamA PF00892.15 KLO04028.1 - 0.028 14.4 0.3 0.14 12.1 0.0 2.1 2 0 0 2 2 2 0 EamA-like transporter family DUF566 PF04484.7 KLO04030.1 - 4.6 6.6 7.8 5.5 6.4 5.4 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF566) F-box PF00646.28 KLO04031.1 - 0.057 13.1 0.5 0.84 9.3 0.0 2.9 3 0 0 3 3 3 0 F-box domain CDC45 PF02724.9 KLO04032.1 - 0.18 9.7 1.0 0.27 9.2 0.7 1.1 1 0 0 1 1 1 0 CDC45-like protein RR_TM4-6 PF06459.7 KLO04032.1 - 9.8 5.9 11.8 15 5.3 8.2 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 RNase_H PF00075.19 KLO04041.1 - 0.0016 18.7 0.1 0.0027 18.0 0.0 1.4 1 0 0 1 1 1 1 RNase H zf-RVT PF13966.1 KLO04041.1 - 0.096 13.0 0.0 0.18 12.1 0.0 1.6 1 1 0 1 1 1 0 zinc-binding in reverse transcriptase PAM2 PF07145.10 KLO04043.1 - 0.023 14.1 2.1 0.081 12.4 1.4 1.9 1 0 0 1 1 1 0 Ataxin-2 C-terminal region BTB PF00651.26 KLO04044.1 - 0.043 13.7 0.0 0.066 13.2 0.0 1.4 1 0 0 1 1 1 0 BTB/POZ domain GRIP PF01465.15 KLO04044.1 - 0.13 11.8 0.0 0.24 10.9 0.0 1.4 1 0 0 1 1 1 0 GRIP domain HTH_Tnp_Tc5 PF03221.11 KLO04048.1 - 5.2e-09 35.7 0.0 1.3e-08 34.4 0.0 1.8 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain HTH_23 PF13384.1 KLO04048.1 - 0.0003 20.3 0.6 0.092 12.4 0.0 3.8 3 1 0 3 3 3 1 Homeodomain-like domain Sigma70_r4 PF04545.11 KLO04048.1 - 0.0021 17.3 0.2 0.012 14.9 0.0 2.3 3 0 0 3 3 3 1 Sigma-70, region 4 HTH_24 PF13412.1 KLO04048.1 - 0.0058 15.9 0.0 0.23 10.9 0.0 2.3 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding HTH_Tnp_4 PF13613.1 KLO04048.1 - 0.0065 15.9 0.0 0.013 15.0 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix of DDE superfamily endonuclease HTH_28 PF13518.1 KLO04048.1 - 0.022 14.7 0.4 0.47 10.4 0.0 2.9 3 0 0 3 3 3 0 Helix-turn-helix domain MarR PF01047.17 KLO04048.1 - 0.055 13.1 0.0 0.16 11.7 0.0 1.8 1 0 0 1 1 1 0 MarR family MarR_2 PF12802.2 KLO04048.1 - 0.061 12.9 0.0 0.27 10.9 0.0 2.0 2 0 0 2 2 2 0 MarR family Sigma70_r4_2 PF08281.7 KLO04048.1 - 0.077 12.4 0.0 5 6.6 0.0 2.5 2 1 0 2 2 2 0 Sigma-70, region 4 HTH_7 PF02796.10 KLO04048.1 - 0.08 12.8 0.1 1.7 8.5 0.0 2.3 2 0 0 2 2 2 0 Helix-turn-helix domain of resolvase DUF2481 PF10654.4 KLO04048.1 - 0.099 12.3 0.0 0.28 10.8 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2481) HTH_38 PF13936.1 KLO04048.1 - 0.2 11.2 1.1 1.1 8.8 0.1 2.3 2 0 0 2 2 2 0 Helix-turn-helix domain Sigma70_ECF PF07638.6 KLO04051.1 - 0.12 12.0 0.0 0.13 11.8 0.0 1.1 1 0 0 1 1 1 0 ECF sigma factor WD40 PF00400.27 KLO04052.1 - 5.3e-05 22.9 3.2 0.013 15.3 0.1 2.4 2 0 0 2 2 2 2 WD domain, G-beta repeat Skp1 PF01466.14 KLO04053.1 - 2.4e-20 72.3 0.0 3.7e-20 71.7 0.0 1.3 1 0 0 1 1 1 1 Skp1 family, dimerisation domain Skp1_POZ PF03931.10 KLO04053.1 - 1.7e-10 40.8 0.0 2.7e-10 40.1 0.0 1.3 1 0 0 1 1 1 1 Skp1 family, tetramerisation domain BTB PF00651.26 KLO04053.1 - 0.035 14.0 0.1 0.23 11.4 0.1 2.1 1 1 0 1 1 1 0 BTB/POZ domain Spt5_N PF11942.3 KLO04056.1 - 8 7.1 6.4 19 5.9 4.4 1.6 1 1 0 1 1 1 0 Spt5 transcription elongation factor, acidic N-terminal CENP-F_leu_zip PF10473.4 KLO04058.1 - 0.039 13.8 5.2 0.059 13.2 3.6 1.3 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF4355 PF14265.1 KLO04058.1 - 0.85 9.5 7.3 1.4 8.9 5.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4355) DUF3505 PF12013.3 KLO04060.1 - 0.062 13.5 0.0 0.11 12.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3505) Xan_ur_permease PF00860.15 KLO04061.1 - 1.5e-26 92.8 13.4 3.3e-21 75.2 5.3 2.0 2 0 0 2 2 2 2 Permease family DUF3816 PF12822.2 KLO04061.1 - 0.00071 19.5 0.9 0.00071 19.5 0.7 2.4 1 1 0 2 2 2 1 Protein of unknown function (DUF3816) DUF4561 PF15120.1 KLO04062.1 - 0.024 14.0 0.0 0.036 13.5 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4561) Daxx PF03344.10 KLO04063.1 - 0.15 10.5 12.3 0.21 10.0 8.5 1.2 1 0 0 1 1 1 0 Daxx Family Sigma70_ner PF04546.8 KLO04063.1 - 2.1 7.9 12.2 0.2 11.2 5.2 1.7 2 0 0 2 2 2 0 Sigma-70, non-essential region WD40 PF00400.27 KLO04064.1 - 1.1e-11 44.1 5.9 4.9e-06 26.2 0.0 3.2 3 0 0 3 3 3 3 WD domain, G-beta repeat CECR6_TMEM121 PF14997.1 KLO04065.1 - 0.11 12.0 0.0 0.14 11.7 0.0 1.2 1 0 0 1 1 1 0 CECR6/TMEM121 family Daxx PF03344.10 KLO04066.1 - 0.097 11.1 7.7 0.14 10.5 5.4 1.2 1 0 0 1 1 1 0 Daxx Family NOA36 PF06524.7 KLO04066.1 - 3 7.0 10.1 5.8 6.0 7.0 1.4 1 0 0 1 1 1 0 NOA36 protein KOW PF00467.24 KLO04073.1 - 4.9e-07 29.2 17.4 0.13 12.0 0.6 5.6 5 0 0 5 5 5 4 KOW motif AP_endonuc_2 PF01261.19 KLO04076.1 - 0.044 13.0 0.1 0.047 12.9 0.0 1.0 1 0 0 1 1 1 0 Xylose isomerase-like TIM barrel Helicase_C PF00271.26 KLO04077.1 - 2.8e-08 33.4 0.0 3.6e-08 33.1 0.0 1.2 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 KLO04078.1 - 0.0015 18.0 0.0 0.0017 17.8 0.0 1.1 1 0 0 1 1 1 1 DEAD/DEAH box helicase WD40 PF00400.27 KLO04086.1 - 2.8e-07 30.1 9.0 0.00086 19.1 0.1 4.3 5 0 0 5 5 5 2 WD domain, G-beta repeat Coatomer_WDAD PF04053.9 KLO04086.1 - 0.0075 15.1 0.1 0.097 11.4 0.0 2.0 2 0 0 2 2 2 1 Coatomer WD associated region HTH_Tnp_Tc5 PF03221.11 KLO04087.1 - 5.7e-12 45.2 0.1 2.1e-11 43.4 0.1 2.1 1 1 1 2 2 2 1 Tc5 transposase DNA-binding domain CENP-B_N PF04218.8 KLO04087.1 - 9.9e-07 28.0 0.5 7.7e-06 25.2 0.1 2.6 2 1 1 3 3 3 1 CENP-B N-terminal DNA-binding domain Sigma70_r4 PF04545.11 KLO04087.1 - 0.0075 15.5 0.0 0.1 11.9 0.0 2.4 2 0 0 2 2 2 1 Sigma-70, region 4 HTH_23 PF13384.1 KLO04087.1 - 0.026 14.1 0.0 0.35 10.6 0.0 2.7 2 1 1 3 3 3 0 Homeodomain-like domain HTH_3 PF01381.17 KLO04087.1 - 0.053 13.3 0.1 0.55 10.1 0.0 2.3 2 0 0 2 2 2 0 Helix-turn-helix HTH_Crp_2 PF13545.1 KLO04087.1 - 0.1 12.4 0.0 0.24 11.1 0.0 1.6 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain WD40 PF00400.27 KLO04090.1 - 3.9e-15 55.0 1.3 9.6e-07 28.4 0.2 5.1 5 0 0 5 5 5 3 WD domain, G-beta repeat DUF808 PF05661.7 KLO04090.1 - 0.055 12.2 0.0 0.091 11.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF808) PQQ_2 PF13360.1 KLO04090.1 - 0.079 12.4 0.1 1.2 8.4 0.0 2.5 2 1 0 2 2 2 0 PQQ-like domain BTB PF00651.26 KLO04091.1 - 8.1e-05 22.5 0.0 0.00014 21.7 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain TMCO5 PF14992.1 KLO04093.1 - 0.0091 15.1 0.1 0.0099 15.0 0.0 1.1 1 0 0 1 1 1 1 TMCO5 family Lzipper-MIP1 PF14389.1 KLO04093.1 - 0.062 13.4 0.3 0.17 11.9 0.0 1.8 2 0 0 2 2 2 0 Leucine-zipper of ternary complex factor MIP1 XkdW PF09636.5 KLO04093.1 - 0.087 12.6 0.1 7.6 6.4 0.0 2.1 2 0 0 2 2 2 0 XkdW protein VPS11_C PF12451.3 KLO04094.1 - 0.019 14.7 0.0 0.032 14.1 0.0 1.3 1 0 0 1 1 1 0 Vacuolar protein sorting protein 11 C terminal zf-MYND PF01753.13 KLO04095.1 - 4.7e-06 26.3 14.9 1.2e-05 25.0 10.3 1.8 1 0 0 1 1 1 1 MYND finger Zn_Tnp_IS1595 PF12760.2 KLO04098.1 - 0.035 13.9 0.4 0.28 11.0 0.0 2.3 2 0 0 2 2 2 0 Transposase zinc-ribbon domain COG7 PF10191.4 KLO04099.1 - 0.032 12.1 0.0 0.046 11.6 0.0 1.1 1 0 0 1 1 1 0 Golgi complex component 7 (COG7) BAH PF01426.13 KLO04100.1 - 4.2e-06 26.5 0.4 7.5e-06 25.6 0.3 1.4 1 0 0 1 1 1 1 BAH domain PIF1 PF05970.9 KLO04102.1 - 2.6e-09 36.5 0.1 4.7e-09 35.6 0.0 1.3 1 1 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.1 KLO04102.1 - 5.7e-07 29.3 0.0 1.1e-06 28.3 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 KLO04102.1 - 7.6e-05 22.3 0.0 0.0001 22.0 0.0 1.2 1 0 0 1 1 1 1 Part of AAA domain Bac_DnaA PF00308.13 KLO04102.1 - 0.00045 19.9 0.1 0.037 13.6 0.0 2.0 2 0 0 2 2 2 1 Bacterial dnaA protein AAA PF00004.24 KLO04102.1 - 0.00065 19.9 0.1 0.0016 18.6 0.0 1.6 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 KLO04102.1 - 0.0096 16.0 0.2 0.024 14.7 0.1 1.6 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.9 KLO04102.1 - 0.011 15.5 0.1 0.26 11.0 0.0 2.0 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Zeta_toxin PF06414.7 KLO04102.1 - 0.013 14.6 0.0 0.018 14.1 0.0 1.1 1 0 0 1 1 1 0 Zeta toxin IstB_IS21 PF01695.12 KLO04102.1 - 0.023 14.1 0.1 0.13 11.6 0.0 1.9 2 0 0 2 2 2 0 IstB-like ATP binding protein NTPase_1 PF03266.10 KLO04102.1 - 0.026 14.2 0.0 0.22 11.2 0.0 2.0 2 0 0 2 2 2 0 NTPase RNA_helicase PF00910.17 KLO04102.1 - 0.13 12.4 0.0 0.21 11.7 0.0 1.3 1 0 0 1 1 1 0 RNA helicase Mago-bind PF09282.5 KLO04103.1 - 0.18 11.4 1.0 1 8.9 0.3 2.6 2 0 0 2 2 2 0 Mago binding Stc1 PF12898.2 KLO04113.1 - 0.099 12.7 0.5 0.17 11.9 0.3 1.4 1 0 0 1 1 1 0 Stc1 domain zf-UBR PF02207.15 KLO04113.1 - 1.6 8.4 7.4 0.57 9.9 1.2 2.6 3 0 0 3 3 3 0 Putative zinc finger in N-recognin (UBR box) DUF1689 PF07954.6 KLO04116.1 - 1.3 8.9 3.8 7.1 6.4 0.2 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1689) LRR_8 PF13855.1 KLO04118.1 - 8.6e-06 25.4 0.9 0.32 10.7 0.1 4.1 3 0 0 3 3 3 2 Leucine rich repeat F-box-like PF12937.2 KLO04118.1 - 3.2e-05 23.5 0.9 0.00023 20.8 0.2 2.7 2 0 0 2 2 2 1 F-box-like LRR_4 PF12799.2 KLO04118.1 - 1.2 8.8 4.9 38 4.0 0.2 4.2 3 2 1 4 4 4 0 Leucine Rich repeats (2 copies) Phage_integrase PF00589.17 KLO04126.1 - 0.0022 17.6 0.0 0.0025 17.4 0.0 1.1 1 0 0 1 1 1 1 Phage integrase family Acyl_transf_1 PF00698.16 KLO04126.1 - 0.3 10.3 1.5 0.34 10.1 1.0 1.1 1 0 0 1 1 1 0 Acyl transferase domain zf-RING_UBOX PF13445.1 KLO04129.1 - 1.5e-06 27.7 0.7 2.5e-06 27.0 0.1 1.8 1 1 1 2 2 2 1 RING-type zinc-finger She9_MDM33 PF05546.6 KLO04129.1 - 0.00014 21.5 0.6 0.00019 21.0 0.4 1.1 1 0 0 1 1 1 1 She9 / Mdm33 family zf-Nse PF11789.3 KLO04129.1 - 0.0014 18.1 1.4 0.0024 17.3 1.0 1.4 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit YscO PF07321.7 KLO04129.1 - 0.0073 16.1 3.6 0.011 15.6 2.5 1.2 1 0 0 1 1 1 1 Type III secretion protein YscO DUF4527 PF15030.1 KLO04129.1 - 0.019 14.2 0.4 0.024 13.9 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4527) zf-RING_2 PF13639.1 KLO04129.1 - 0.02 14.7 0.6 0.037 13.8 0.4 1.5 1 1 0 1 1 1 0 Ring finger domain DUF3359 PF11839.3 KLO04129.1 - 0.041 14.2 0.9 0.07 13.4 0.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3359) GAGA_bind PF06217.7 KLO04129.1 - 0.098 12.6 0.1 0.1 12.5 0.1 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family zf-C3HC4_2 PF13923.1 KLO04129.1 - 0.35 10.9 3.6 2 8.5 2.5 2.2 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Rtf2 PF04641.7 KLO04129.1 - 0.63 9.2 5.6 0.68 9.0 0.1 2.0 1 1 1 2 2 2 0 Rtf2 RING-finger DUF4200 PF13863.1 KLO04130.1 - 0.019 14.9 3.8 0.019 14.9 2.6 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) RBD-FIP PF09457.5 KLO04130.1 - 0.034 13.9 1.4 0.084 12.6 0.3 2.2 2 1 0 2 2 2 0 FIP domain DUF4211 PF13926.1 KLO04130.1 - 0.043 13.2 0.1 0.074 12.4 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4211) PAM2 PF07145.10 KLO04131.1 - 0.016 14.6 2.7 0.059 12.8 1.9 2.0 1 0 0 1 1 1 0 Ataxin-2 C-terminal region AAA_16 PF13191.1 KLO04132.1 - 1.4e-07 31.6 0.0 6e-07 29.6 0.0 2.1 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 KLO04132.1 - 2.9e-07 30.7 0.0 9.5e-07 29.0 0.0 1.9 1 0 0 1 1 1 1 AAA domain NACHT PF05729.7 KLO04132.1 - 4.4e-07 29.6 0.0 8.7e-07 28.7 0.0 1.4 1 0 0 1 1 1 1 NACHT domain PPV_E1_C PF00519.12 KLO04132.1 - 0.0047 15.6 0.0 0.0082 14.8 0.0 1.2 1 0 0 1 1 1 1 Papillomavirus helicase Arch_ATPase PF01637.13 KLO04132.1 - 0.0049 16.6 0.1 0.024 14.3 0.0 2.2 2 0 0 2 2 2 1 Archaeal ATPase RNA_helicase PF00910.17 KLO04132.1 - 0.012 15.7 0.0 0.036 14.2 0.0 1.8 1 0 0 1 1 1 0 RNA helicase AAA_25 PF13481.1 KLO04132.1 - 0.015 14.6 0.0 0.038 13.3 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA PF00004.24 KLO04132.1 - 0.019 15.1 0.0 0.49 10.5 0.0 3.0 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 KLO04132.1 - 0.045 14.5 0.0 0.27 12.0 0.0 2.4 1 1 0 1 1 1 0 AAA domain NB-ARC PF00931.17 KLO04132.1 - 0.057 12.2 0.0 0.2 10.5 0.0 1.9 2 0 0 2 2 2 0 NB-ARC domain DUF4042 PF13251.1 KLO04132.1 - 0.14 11.6 0.0 15 4.9 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4042) SET PF00856.23 KLO04133.1 - 1.3e-09 38.5 0.0 1.1e-08 35.4 0.0 2.4 2 0 0 2 2 2 1 SET domain TPR_11 PF13414.1 KLO04133.1 - 0.0011 18.5 0.0 0.0032 17.0 0.0 1.7 1 0 0 1 1 1 1 TPR repeat SAF PF08666.7 KLO04133.1 - 0.13 12.6 0.0 14 6.1 0.0 2.6 2 0 0 2 2 2 0 SAF domain NACHT PF05729.7 KLO04134.1 - 0.00015 21.4 0.0 0.0007 19.2 0.0 2.1 1 1 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 KLO04134.1 - 0.0055 16.7 0.0 0.031 14.2 0.0 2.3 1 1 0 1 1 1 1 AAA ATPase domain Parvo_NS1 PF01057.12 KLO04134.1 - 0.077 11.8 0.1 0.14 11.0 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 V_ATPase_I PF01496.14 KLO04139.1 - 4.3 5.0 9.9 6.6 4.4 6.9 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family HTH_Tnp_Tc3_2 PF01498.13 KLO04146.1 - 1.8e-05 24.6 0.2 2.5e-05 24.2 0.1 1.3 1 1 0 1 1 1 1 Transposase HTH_33 PF13592.1 KLO04146.1 - 4.7e-05 22.8 0.1 5.5e-05 22.6 0.0 1.1 1 0 0 1 1 1 1 Winged helix-turn helix DDE_Tnp_ISAZ013 PF07592.6 KLO04146.1 - 0.0036 16.0 0.1 0.0041 15.9 0.0 1.0 1 0 0 1 1 1 1 Rhodopirellula transposase DDE domain HTH_29 PF13551.1 KLO04146.1 - 0.019 15.1 0.0 0.033 14.3 0.0 1.4 1 0 0 1 1 1 0 Winged helix-turn helix HTH_Tnp_IS630 PF01710.11 KLO04146.1 - 0.058 13.0 0.1 0.07 12.8 0.1 1.2 1 0 0 1 1 1 0 Transposase Ribonuclease_P PF00825.13 KLO04146.1 - 0.11 12.3 0.1 0.14 12.0 0.1 1.3 1 1 0 1 1 1 0 Ribonuclease P DDE_3 PF13358.1 KLO04147.1 - 1.4e-09 37.8 0.0 1.4e-09 37.8 0.0 1.0 1 0 0 1 1 1 1 DDE superfamily endonuclease DUF4343 PF14243.1 KLO04147.1 - 0.063 13.1 0.0 0.07 12.9 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4343) DDE_3 PF13358.1 KLO04148.1 - 1.5e-07 31.2 0.0 2.1e-07 30.7 0.0 1.3 1 1 0 1 1 1 1 DDE superfamily endonuclease CtaG_Cox11 PF04442.9 KLO04148.1 - 0.11 12.2 0.0 0.11 12.2 0.0 1.0 1 0 0 1 1 1 0 Cytochrome c oxidase assembly protein CtaG/Cox11 DUF998 PF06197.8 KLO04150.1 - 0.072 12.3 0.0 0.1 11.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF998) Frankia_peptide PF14407.1 KLO04150.1 - 0.083 12.6 0.5 0.15 11.7 0.3 1.4 1 0 0 1 1 1 0 Ribosomally synthesized peptide prototyped by Frankia Franean1_4349. OCC1 PF15506.1 KLO04152.1 - 0.13 12.1 0.1 0.22 11.4 0.1 1.3 1 0 0 1 1 1 0 OCC1 family TPR_12 PF13424.1 KLO04153.1 - 5.3e-19 67.9 14.5 0.09 12.7 0.0 10.8 5 3 6 11 11 11 7 Tetratricopeptide repeat TPR_11 PF13414.1 KLO04153.1 - 1.4e-07 31.0 14.4 4.7 6.9 0.0 9.1 5 3 4 10 10 10 3 TPR repeat TPR_14 PF13428.1 KLO04153.1 - 4.4e-06 26.8 22.9 3.1 8.6 0.2 10.4 9 2 2 11 11 11 1 Tetratricopeptide repeat TPR_16 PF13432.1 KLO04153.1 - 7.3e-05 23.3 20.0 7.6 7.3 0.0 9.3 6 3 5 11 11 11 2 Tetratricopeptide repeat TPR_2 PF07719.12 KLO04153.1 - 0.0026 17.5 15.5 0.63 10.1 0.0 8.2 10 0 0 10 10 10 1 Tetratricopeptide repeat TPR_1 PF00515.23 KLO04153.1 - 0.0056 16.2 7.3 7 6.4 0.0 7.0 9 0 0 9 9 9 1 Tetratricopeptide repeat Osmo_CC PF08946.5 KLO04153.1 - 1.4 9.0 4.8 17 5.5 0.0 3.9 4 0 0 4 4 4 0 Osmosensory transporter coiled coil Cob_adeno_trans PF01923.13 KLO04153.1 - 3.6 7.3 7.1 23 4.7 0.1 3.7 5 0 0 5 5 5 0 Cobalamin adenosyltransferase BCIP PF13862.1 KLO04155.1 - 2e-10 40.5 0.1 2.6e-10 40.1 0.1 1.1 1 0 0 1 1 1 1 p21-C-terminal region-binding protein Chorion_3 PF05387.6 KLO04155.1 - 0.07 12.5 0.0 0.07 12.5 0.0 1.0 1 0 0 1 1 1 0 Chorion family 3 HMG_box PF00505.14 KLO04159.1 - 3.9e-05 23.8 0.1 6.9e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 KLO04159.1 - 0.00067 19.9 0.0 0.0012 19.1 0.0 1.5 1 0 0 1 1 1 1 HMG-box domain Toxin_1 PF00087.16 KLO04164.1 - 0.73 10.2 4.9 0.91 9.9 3.4 1.3 1 0 0 1 1 1 0 Snake toxin Auto_anti-p27 PF06677.7 KLO04164.1 - 1.9 8.3 6.9 0.17 11.6 0.6 2.0 2 0 0 2 2 2 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) DHC PF09626.5 KLO04165.1 - 0.00074 20.1 0.2 0.0021 18.7 0.0 1.7 2 0 0 2 2 2 1 Dihaem cytochrome c zf-MYND PF01753.13 KLO04170.1 - 8.8e-06 25.4 5.3 8.8e-06 25.4 3.7 1.9 1 1 0 1 1 1 1 MYND finger DNA_pol_A_exo1 PF01612.15 KLO04171.1 - 9.1e-17 61.0 0.0 1.3e-16 60.6 0.0 1.2 1 0 0 1 1 1 1 3'-5' exonuclease DEAD PF00270.24 KLO04178.1 - 2.1e-07 30.5 0.0 2.6e-07 30.2 0.0 1.1 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.10 KLO04178.1 - 5.4e-05 23.1 0.0 6.1e-05 22.9 0.0 1.1 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Rhamno_transf PF11316.3 KLO04180.1 - 0.036 13.2 0.4 0.071 12.2 0.3 1.5 1 1 0 1 1 1 0 Putative rhamnosyl transferase DUF2256 PF10013.4 KLO04181.1 - 0.096 12.4 2.3 20 5.0 0.1 3.1 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2256) BCIP PF13862.1 KLO04183.1 - 2e-10 40.5 0.1 2.6e-10 40.1 0.1 1.1 1 0 0 1 1 1 1 p21-C-terminal region-binding protein Chorion_3 PF05387.6 KLO04183.1 - 0.07 12.5 0.0 0.07 12.5 0.0 1.0 1 0 0 1 1 1 0 Chorion family 3 Bromo_MP PF01573.11 KLO04184.1 - 4.3 6.2 11.7 0.37 9.7 1.6 2.3 2 0 0 2 2 2 0 Bromovirus movement protein DUF3787 PF12655.2 KLO04189.1 - 0.017 14.8 0.2 0.037 13.7 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3787) ADSL_C PF10397.4 KLO04189.1 - 0.02 14.9 0.2 0.063 13.2 0.2 1.9 1 1 0 1 1 1 0 Adenylosuccinate lyase C-terminus Helicase_C PF00271.26 KLO04191.1 - 1.6e-15 56.7 0.2 2.7e-15 55.9 0.1 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Sporozoite_P67 PF05642.6 KLO04191.1 - 0.52 8.1 5.2 0.67 7.7 3.6 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Herpes_DNAp_acc PF04929.7 KLO04191.1 - 7.5 5.4 7.3 8.9 5.1 3.2 1.9 2 0 0 2 2 2 0 Herpes DNA replication accessory factor PHD PF00628.24 KLO04192.1 - 0.0003 20.4 4.2 0.00084 18.9 1.1 2.5 2 0 0 2 2 2 1 PHD-finger BAH PF01426.13 KLO04192.1 - 0.00043 20.0 0.1 0.0027 17.4 0.1 2.2 1 1 0 1 1 1 1 BAH domain zf-RING_2 PF13639.1 KLO04192.1 - 2.4 8.0 6.8 3.6 7.4 3.5 2.1 2 0 0 2 2 2 0 Ring finger domain WD40 PF00400.27 KLO04195.1 - 5.5e-12 45.0 2.8 1.2e-06 28.2 0.0 4.4 4 0 0 4 4 4 3 WD domain, G-beta repeat PQQ_2 PF13360.1 KLO04195.1 - 0.13 11.7 0.0 1.9 7.8 0.0 2.2 2 0 0 2 2 2 0 PQQ-like domain E3_UbLigase_R4 PF13764.1 KLO04197.1 - 0.062 11.1 0.0 0.062 11.1 0.0 1.0 1 0 0 1 1 1 0 E3 ubiquitin-protein ligase UBR4 Spt5_N PF11942.3 KLO04200.1 - 0.02 15.5 12.5 0.02 15.5 8.7 3.3 2 1 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal DUF3480 PF11979.3 KLO04200.1 - 0.12 11.0 0.8 0.19 10.2 0.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3480) Herpes_UL95 PF03038.9 KLO04203.1 - 0.024 13.5 0.1 0.027 13.3 0.0 1.1 1 0 0 1 1 1 0 UL95 family zf-MYND PF01753.13 KLO04209.1 - 7.1e-07 28.9 7.6 1.7e-06 27.7 5.2 1.7 1 0 0 1 1 1 1 MYND finger Sulfotransfer_1 PF00685.22 KLO04210.1 - 0.058 12.6 0.0 0.079 12.1 0.0 1.2 1 0 0 1 1 1 0 Sulfotransferase domain zf-UBR PF02207.15 KLO04211.1 - 0.85 9.3 10.3 0.18 11.5 2.7 2.7 3 0 0 3 3 3 0 Putative zinc finger in N-recognin (UBR box) Transposase_21 PF02992.9 KLO04216.1 - 7.3e-10 38.3 0.0 1.5e-09 37.2 0.0 1.4 1 0 0 1 1 1 1 Transposase family tnp2 DUF4218 PF13960.1 KLO04216.1 - 2.3e-06 27.0 0.1 4.8e-06 26.0 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4218) zf-CCHC PF00098.18 KLO04220.1 - 0.033 14.1 3.2 0.059 13.3 2.3 1.4 1 0 0 1 1 1 0 Zinc knuckle YwqJ-deaminase PF14431.1 KLO04220.1 - 0.055 13.3 0.1 0.098 12.5 0.1 1.4 1 0 0 1 1 1 0 YwqJ-like deaminase gag_pre-integrs PF13976.1 KLO04221.1 - 4.4e-11 42.2 0.2 6e-11 41.8 0.1 1.2 1 0 0 1 1 1 1 GAG-pre-integrase domain rve PF00665.21 KLO04221.1 - 0.081 13.0 0.2 2.1 8.5 0.0 2.0 2 0 0 2 2 2 0 Integrase core domain gag_pre-integrs PF13976.1 KLO04223.1 - 5.5e-08 32.3 0.0 8.4e-08 31.7 0.0 1.3 1 0 0 1 1 1 1 GAG-pre-integrase domain TraV PF09676.5 KLO04224.1 - 0.019 15.6 0.7 0.019 15.6 0.5 1.2 1 0 0 1 1 1 0 Type IV conjugative transfer system lipoprotein (TraV) Macoilin PF09726.4 KLO04224.1 - 5.2 5.2 7.7 6.1 4.9 5.4 1.0 1 0 0 1 1 1 0 Transmembrane protein UBN2_2 PF14227.1 KLO04225.1 - 0.0019 17.7 0.0 0.0027 17.2 0.0 1.2 1 1 0 1 1 1 1 gag-polypeptide of LTR copia-type BTB PF00651.26 KLO04229.1 - 4.4e-06 26.6 0.0 2.4e-05 24.3 0.0 1.8 1 1 0 1 1 1 1 BTB/POZ domain BTB PF00651.26 KLO04230.1 - 2.8e-05 24.0 0.0 3.5e-05 23.7 0.0 1.1 1 0 0 1 1 1 1 BTB/POZ domain Chromo PF00385.19 KLO04232.1 - 1e-08 34.7 0.1 1.1e-08 34.5 0.1 1.0 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Patatin PF01734.17 KLO04234.1 - 3.6e-05 23.7 0.0 0.0099 15.8 0.0 2.2 2 0 0 2 2 2 2 Patatin-like phospholipase ANTAR PF03861.9 KLO04234.1 - 0.13 11.8 0.1 0.54 9.8 0.0 1.9 2 0 0 2 2 2 0 ANTAR domain Gag_spuma PF03276.9 KLO04236.1 - 0.068 11.4 0.8 0.09 11.0 0.6 1.1 1 0 0 1 1 1 0 Spumavirus gag protein F-box-like PF12937.2 KLO04238.1 - 1.7e-07 30.8 1.0 1.7e-07 30.8 0.7 2.8 3 1 0 3 3 3 1 F-box-like AT_hook PF02178.14 KLO04239.1 - 0.74 9.6 10.4 3.1 7.7 7.2 2.2 1 0 0 1 1 1 0 AT hook motif HSP70 PF00012.15 KLO04240.1 - 1.5e-82 277.4 0.1 1.9e-82 277.1 0.1 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 KLO04240.1 - 1.2e-05 24.0 0.0 1.7e-05 23.5 0.0 1.1 1 0 0 1 1 1 1 MreB/Mbl protein DUF4582 PF15189.1 KLO04240.1 - 0.0062 15.7 0.1 0.0096 15.1 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4582) DDR PF08841.5 KLO04240.1 - 0.0084 14.9 0.1 0.23 10.2 0.0 2.1 2 0 0 2 2 2 1 Diol dehydratase reactivase ATPase-like domain Hydantoinase_A PF01968.13 KLO04240.1 - 0.015 14.4 0.3 0.065 12.3 0.1 1.9 1 1 1 2 2 2 0 Hydantoinase/oxoprolinase HTH_Tnp_Tc3_2 PF01498.13 KLO04241.1 - 3.3e-05 23.8 0.1 4.5e-05 23.4 0.1 1.3 1 1 0 1 1 1 1 Transposase HTH_33 PF13592.1 KLO04241.1 - 6.3e-05 22.4 0.1 7.4e-05 22.2 0.1 1.2 1 0 0 1 1 1 1 Winged helix-turn helix DDE_Tnp_ISAZ013 PF07592.6 KLO04241.1 - 0.0041 15.9 0.0 0.0044 15.8 0.0 1.0 1 0 0 1 1 1 1 Rhodopirellula transposase DDE domain HTH_29 PF13551.1 KLO04241.1 - 0.046 13.8 0.1 0.083 13.0 0.0 1.4 2 0 0 2 2 2 0 Winged helix-turn helix HTH_Tnp_IS630 PF01710.11 KLO04241.1 - 0.063 12.9 0.1 0.078 12.6 0.0 1.2 1 0 0 1 1 1 0 Transposase DDE_3 PF13358.1 KLO04242.1 - 1.4e-09 37.8 0.0 1.4e-09 37.8 0.0 1.0 1 0 0 1 1 1 1 DDE superfamily endonuclease DUF4343 PF14243.1 KLO04242.1 - 0.063 13.1 0.0 0.07 12.9 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4343) DDE_3 PF13358.1 KLO04243.1 - 5.9e-08 32.5 0.0 8.1e-08 32.1 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease CtaG_Cox11 PF04442.9 KLO04243.1 - 0.04 13.7 0.0 0.042 13.6 0.0 1.0 1 0 0 1 1 1 0 Cytochrome c oxidase assembly protein CtaG/Cox11 Phage_integrase PF00589.17 KLO04247.1 - 2.8e-05 23.8 0.0 0.00014 21.5 0.0 2.1 2 0 0 2 2 2 1 Phage integrase family WD40 PF00400.27 KLO04253.1 - 0.063 13.1 0.2 0.83 9.6 0.0 2.3 2 0 0 2 2 2 0 WD domain, G-beta repeat DUF4218 PF13960.1 KLO04254.1 - 0.00046 19.6 0.1 0.00086 18.7 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4218) Pkinase PF00069.20 KLO04255.1 - 1.5e-13 50.5 0.0 1e-12 47.7 0.0 1.9 1 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 KLO04255.1 - 0.0036 16.4 0.0 0.0069 15.4 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase VP9 PF09625.5 KLO04255.1 - 0.052 13.3 0.0 0.098 12.4 0.0 1.4 1 0 0 1 1 1 0 VP9 protein Kdo PF06293.9 KLO04255.1 - 0.072 12.1 0.0 0.13 11.3 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF2664 PF10867.3 KLO04261.1 - 0.00035 21.1 0.3 0.00089 19.8 0.2 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2664) Trs65 PF12735.2 KLO04263.1 - 0.092 12.0 3.8 0.15 11.3 2.6 1.2 1 0 0 1 1 1 0 TRAPP trafficking subunit Trs65 KOW PF00467.24 KLO04264.1 - 0.0002 20.9 2.1 0.016 14.9 0.1 2.5 2 0 0 2 2 2 2 KOW motif DUF3912 PF13051.1 KLO04264.1 - 0.025 14.2 0.0 0.055 13.2 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3912) SNARE_assoc PF09335.6 KLO04269.1 - 0.049 13.8 1.4 0.057 13.6 1.0 1.2 1 0 0 1 1 1 0 SNARE associated Golgi protein Ribosomal_L14e PF01929.12 KLO04270.1 - 0.05 13.9 0.2 0.078 13.3 0.1 1.3 1 0 0 1 1 1 0 Ribosomal protein L14 zf-MYND PF01753.13 KLO04272.1 - 5.9e-07 29.2 3.6 5.9e-07 29.2 2.5 1.8 2 0 0 2 2 2 1 MYND finger BcrAD_BadFG PF01869.15 KLO04274.1 - 0.29 10.3 0.0 0.44 9.8 0.0 1.2 1 0 0 1 1 1 0 BadF/BadG/BcrA/BcrD ATPase family F-box-like PF12937.2 KLO04278.1 - 7.3e-08 32.0 0.1 7.5e-07 28.7 0.0 2.3 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 KLO04278.1 - 0.0048 16.5 0.6 0.0048 16.5 0.4 2.0 2 0 0 2 2 2 1 F-box domain HTH_Tnp_Tc5 PF03221.11 KLO04279.1 - 1.9e-06 27.5 0.0 8.3e-06 25.5 0.0 2.0 2 1 0 2 2 2 1 Tc5 transposase DNA-binding domain PSD5 PF07637.6 KLO04279.1 - 0.051 13.6 0.1 8.1 6.5 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1595) HTH_29 PF13551.1 KLO04279.1 - 0.06 13.4 0.0 0.11 12.6 0.0 1.5 1 1 0 1 1 1 0 Winged helix-turn helix DDE_1 PF03184.14 KLO04280.1 - 4.1e-31 107.8 0.0 5.1e-31 107.5 0.0 1.0 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_3 PF13358.1 KLO04280.1 - 0.013 15.2 0.0 0.02 14.6 0.0 1.2 1 0 0 1 1 1 0 DDE superfamily endonuclease DUF3486 PF11985.3 KLO04281.1 - 0.032 14.3 0.2 0.034 14.2 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3486) CTK3 PF12243.3 KLO04283.1 - 1.3e-26 92.8 0.1 1.4e-26 92.7 0.0 1.0 1 0 0 1 1 1 1 CTD kinase subunit gamma CTK3 Dimer_Tnp_hAT PF05699.9 KLO04286.1 - 3.8e-18 64.8 0.1 8.2e-18 63.8 0.0 1.6 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region p450 PF00067.17 KLO04286.1 - 7.5e-17 60.9 0.0 1.3e-16 60.2 0.0 1.4 1 0 0 1 1 1 1 Cytochrome P450 DUF4413 PF14372.1 KLO04286.1 - 0.028 14.4 0.0 0.077 12.9 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4413) WD40 PF00400.27 KLO04289.1 - 3.9e-08 32.8 4.9 0.0036 17.1 0.0 4.8 5 0 0 5 5 5 2 WD domain, G-beta repeat BBS2_Mid PF14783.1 KLO04289.1 - 0.047 13.4 0.0 0.85 9.4 0.0 2.6 2 0 0 2 2 2 0 Ciliary BBSome complex subunit 2, middle region RAB3GAP2_N PF14655.1 KLO04289.1 - 0.073 12.0 0.0 1.5 7.7 0.0 2.1 2 0 0 2 2 2 0 Rab3 GTPase-activating protein regulatory subunit N-terminus Dfp1_Him1_M PF08630.5 KLO04290.1 - 0.027 14.2 0.5 0.089 12.5 0.1 2.0 2 0 0 2 2 2 0 Dfp1/Him1, central region Chromo PF00385.19 KLO04291.1 - 7.7e-13 47.9 3.5 1.4e-12 47.0 2.5 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain zf-RING_2 PF13639.1 KLO04292.1 - 1.7e-11 43.7 2.1 7.9e-10 38.4 0.4 2.4 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.1 KLO04292.1 - 2.3e-07 30.7 3.1 3.1e-07 30.2 0.4 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 KLO04292.1 - 5.6e-07 29.5 0.1 5.8e-06 26.3 0.0 2.3 2 0 0 2 2 2 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 KLO04292.1 - 2.2e-06 27.2 0.6 2.2e-05 24.0 0.1 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KLO04292.1 - 9.5e-06 25.2 0.6 3.1e-05 23.6 0.1 2.0 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 KLO04292.1 - 5e-05 22.8 1.1 0.00018 21.1 0.1 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 KLO04292.1 - 0.0041 16.7 0.1 0.012 15.3 0.0 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-Apc11 PF12861.2 KLO04292.1 - 0.0068 16.2 0.5 0.014 15.2 0.1 1.7 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_4 PF14447.1 KLO04292.1 - 0.097 12.2 1.1 0.25 10.9 0.7 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.1 KLO04292.1 - 0.26 11.2 2.5 0.26 11.1 0.3 2.1 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING FAM91_N PF14647.1 KLO04297.1 - 0.11 11.5 0.0 0.2 10.6 0.0 1.4 1 0 0 1 1 1 0 FAM91 N-terminus CENP-T PF15511.1 KLO04301.1 - 0.0069 15.6 19.2 0.0073 15.5 13.3 1.0 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T Daxx PF03344.10 KLO04301.1 - 0.0098 14.4 24.8 0.01 14.3 17.2 1.0 1 0 0 1 1 1 1 Daxx Family Nop14 PF04147.7 KLO04301.1 - 0.014 13.3 31.3 0.015 13.2 21.7 1.0 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.9 KLO04301.1 - 0.087 10.8 20.9 0.1 10.5 14.5 1.1 1 0 0 1 1 1 0 CDC45-like protein SDA1 PF05285.7 KLO04301.1 - 0.12 11.6 28.6 0.13 11.5 19.9 1.1 1 0 0 1 1 1 0 SDA1 DUF1510 PF07423.6 KLO04301.1 - 0.13 11.6 17.9 0.15 11.3 12.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) HGTP_anticodon2 PF12745.2 KLO04301.1 - 0.17 11.0 4.1 0.21 10.6 2.8 1.2 1 0 0 1 1 1 0 Anticodon binding domain of tRNAs BUD22 PF09073.5 KLO04301.1 - 0.61 9.1 27.8 0.7 8.8 19.3 1.1 1 0 0 1 1 1 0 BUD22 Spore_coat_CotO PF14153.1 KLO04301.1 - 1.3 8.4 8.0 1.5 8.2 5.5 1.1 1 0 0 1 1 1 0 Spore coat protein CotO Trypan_PARP PF05887.6 KLO04301.1 - 2.6 7.8 18.3 3.6 7.3 12.7 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) SAPS PF04499.10 KLO04301.1 - 3.6 6.1 7.5 3.5 6.1 5.2 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein TFIIF_alpha PF05793.7 KLO04301.1 - 3.9 5.7 31.4 4.4 5.5 21.8 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) SGT1 PF07093.6 KLO04301.1 - 4.1 5.6 15.0 4.9 5.4 10.4 1.1 1 0 0 1 1 1 0 SGT1 protein CDC27 PF09507.5 KLO04301.1 - 6.3 5.9 14.9 6.7 5.8 10.3 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 NACHT PF05729.7 KLO04308.1 - 9.9e-11 41.5 0.0 1.3e-10 41.1 0.0 1.2 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.1 KLO04308.1 - 3.7e-07 30.3 0.0 5e-07 29.9 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA PF00004.24 KLO04308.1 - 1.2e-05 25.5 0.1 9.2e-05 22.6 0.1 1.9 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) NB-ARC PF00931.17 KLO04308.1 - 4.5e-05 22.4 0.4 7.9e-05 21.6 0.3 1.5 1 1 0 1 1 1 1 NB-ARC domain AAA_16 PF13191.1 KLO04308.1 - 5.4e-05 23.2 0.0 0.00013 21.9 0.0 1.6 1 1 0 1 1 1 1 AAA ATPase domain Arch_ATPase PF01637.13 KLO04308.1 - 0.00037 20.2 0.0 0.00048 19.8 0.0 1.0 1 0 0 1 1 1 1 Archaeal ATPase AAA_18 PF13238.1 KLO04308.1 - 0.00059 20.1 0.1 0.0017 18.6 0.1 1.8 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 KLO04308.1 - 0.00079 19.1 0.0 0.0017 18.0 0.0 1.5 1 0 0 1 1 1 1 Part of AAA domain AAA_30 PF13604.1 KLO04308.1 - 0.0008 19.0 0.7 0.00099 18.7 0.5 1.5 1 1 0 1 1 1 1 AAA domain ABC_tran PF00005.22 KLO04308.1 - 0.0019 18.4 0.2 0.0038 17.5 0.1 1.5 1 1 0 1 1 1 1 ABC transporter AAA_17 PF13207.1 KLO04308.1 - 0.0049 17.6 0.3 0.0071 17.1 0.2 1.5 1 1 0 1 1 1 1 AAA domain Parvo_NS1 PF01057.12 KLO04308.1 - 0.0074 15.1 0.4 0.012 14.5 0.3 1.3 1 0 0 1 1 1 1 Parvovirus non-structural protein NS1 APS_kinase PF01583.15 KLO04308.1 - 0.0074 15.9 0.3 0.013 15.1 0.2 1.3 1 0 0 1 1 1 1 Adenylylsulphate kinase PIF1 PF05970.9 KLO04308.1 - 0.029 13.3 0.1 0.051 12.5 0.0 1.4 1 0 0 1 1 1 0 PIF1-like helicase RNA_helicase PF00910.17 KLO04308.1 - 0.029 14.5 0.2 0.055 13.6 0.1 1.6 1 1 0 1 1 1 0 RNA helicase AAA_10 PF12846.2 KLO04308.1 - 0.03 13.7 0.0 0.042 13.2 0.0 1.5 1 1 0 1 1 1 0 AAA-like domain PhoH PF02562.11 KLO04308.1 - 0.039 13.1 0.0 0.04 13.1 0.0 1.2 1 0 0 1 1 1 0 PhoH-like protein TcpQ PF10671.4 KLO04308.1 - 0.051 13.4 0.2 4.1 7.3 0.0 2.5 2 0 0 2 2 2 0 Toxin co-regulated pilus biosynthesis protein Q AAA_33 PF13671.1 KLO04308.1 - 0.069 13.0 0.1 0.083 12.7 0.1 1.3 1 1 0 1 1 1 0 AAA domain Thymidylate_kin PF02223.12 KLO04308.1 - 0.074 12.4 0.0 0.15 11.4 0.0 1.5 1 0 0 1 1 1 0 Thymidylate kinase ArgK PF03308.11 KLO04308.1 - 0.078 11.7 0.1 0.12 11.0 0.1 1.3 1 0 0 1 1 1 0 ArgK protein DUF2075 PF09848.4 KLO04308.1 - 0.083 11.8 0.0 0.091 11.7 0.0 1.2 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) IstB_IS21 PF01695.12 KLO04308.1 - 0.087 12.2 0.3 0.15 11.4 0.1 1.6 1 1 0 1 1 1 0 IstB-like ATP binding protein KAP_NTPase PF07693.9 KLO04308.1 - 0.089 11.7 0.0 0.14 11.0 0.0 1.4 1 1 0 1 1 1 0 KAP family P-loop domain AAA_14 PF13173.1 KLO04308.1 - 0.098 12.5 0.1 0.54 10.1 0.1 2.0 1 1 0 1 1 1 0 AAA domain AAA_29 PF13555.1 KLO04308.1 - 0.1 12.1 0.1 0.18 11.3 0.0 1.3 1 0 0 1 1 1 0 P-loop containing region of AAA domain MobB PF03205.9 KLO04308.1 - 0.13 11.9 0.2 0.3 10.8 0.0 1.6 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_25 PF13481.1 KLO04308.1 - 0.28 10.5 1.2 0.41 10.0 0.8 1.7 1 1 0 1 1 1 0 AAA domain ubiquitin PF00240.18 KLO04315.1 - 6.3e-32 108.7 0.7 8e-32 108.4 0.5 1.1 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 KLO04315.1 - 3.5e-16 58.6 0.2 4.6e-16 58.2 0.2 1.2 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 KLO04315.1 - 3.3e-06 27.2 0.1 1.3e-05 25.3 0.1 1.8 1 1 0 1 1 1 1 Ubiquitin-like domain Rad60-SLD_2 PF13881.1 KLO04315.1 - 0.0039 17.0 0.0 0.0085 15.9 0.0 1.5 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 KLO04315.1 - 0.0053 16.9 0.1 0.0083 16.2 0.0 1.5 1 1 0 1 1 1 1 DUF2407 ubiquitin-like domain TUG-UBL1 PF11470.3 KLO04315.1 - 0.056 13.3 0.0 0.078 12.9 0.0 1.3 1 0 0 1 1 1 0 GLUT4 regulating protein TUG GABP-alpha PF11620.3 KLO04315.1 - 0.091 12.7 0.2 0.1 12.5 0.1 1.1 1 0 0 1 1 1 0 GA-binding protein alpha chain PseudoU_synth_1 PF01416.15 KLO04316.1 - 9.5e-20 70.9 0.0 2e-10 40.9 0.0 2.3 2 0 0 2 2 2 2 tRNA pseudouridine synthase DUF2368 PF10166.4 KLO04319.1 - 0.02 14.4 0.0 0.32 10.5 0.0 2.3 2 0 0 2 2 2 0 Uncharacterised conserved protein (DUF2368) Chromo PF00385.19 KLO04320.1 - 5.5e-10 38.7 0.3 1.1e-09 37.8 0.0 1.6 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain DEAD PF00270.24 KLO04323.1 - 1.7e-07 30.8 0.0 3.8e-07 29.7 0.0 1.6 1 1 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.10 KLO04323.1 - 0.00046 20.0 0.0 0.001 18.9 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.26 KLO04323.1 - 0.00053 19.7 0.0 0.0017 18.1 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain UvrD-helicase PF00580.16 KLO04323.1 - 0.016 14.4 0.1 0.035 13.3 0.1 1.5 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain SecA_DEAD PF07517.9 KLO04323.1 - 0.018 14.3 0.0 0.029 13.6 0.0 1.2 1 0 0 1 1 1 0 SecA DEAD-like domain AAA_19 PF13245.1 KLO04323.1 - 0.044 13.5 0.5 0.15 11.8 0.1 2.1 2 0 0 2 2 2 0 Part of AAA domain TIP_N PF12457.3 KLO04325.1 - 0.054 13.5 0.1 0.079 13.0 0.0 1.2 1 0 0 1 1 1 0 Tuftelin interacting protein N terminal PXPV PF12778.2 KLO04325.1 - 0.53 10.0 6.7 2.1 8.0 4.7 2.1 1 0 0 1 1 1 0 PXPV repeat (3 copies) WD40 PF00400.27 KLO04326.1 - 5.3e-10 38.8 10.2 1.1e-05 25.0 0.0 4.8 4 0 0 4 4 4 3 WD domain, G-beta repeat CcdA PF07362.7 KLO04329.1 - 1.4 8.8 6.8 0.24 11.3 1.8 1.9 2 0 0 2 2 2 0 Post-segregation antitoxin CcdA DDE_1 PF03184.14 KLO04330.1 - 6.4e-23 81.0 0.0 7.9e-23 80.7 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_3 PF13358.1 KLO04330.1 - 0.0039 16.9 0.0 0.008 15.9 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease STE3 PF02076.10 KLO04332.1 - 5.5e-58 196.3 6.1 6.4e-58 196.0 4.2 1.0 1 0 0 1 1 1 1 Pheromone A receptor Flu_NS2 PF00601.14 KLO04333.1 - 0.0039 17.3 0.6 0.0051 16.9 0.4 1.2 1 0 0 1 1 1 1 Influenza non-structural protein (NS2) DUF4509 PF14970.1 KLO04333.1 - 0.011 15.4 0.2 0.013 15.1 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4509) Occludin_ELL PF07303.8 KLO04333.1 - 0.011 16.3 0.5 0.022 15.4 0.4 1.4 1 0 0 1 1 1 0 Occludin homology domain Apolipo_F PF15148.1 KLO04333.1 - 0.047 13.0 0.1 0.051 12.8 0.1 1.1 1 0 0 1 1 1 0 Apolipoprotein F APG6 PF04111.7 KLO04333.1 - 0.1 11.6 2.1 0.098 11.6 1.5 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 V_ATPase_I PF01496.14 KLO04333.1 - 0.13 10.1 2.6 0.13 10.0 1.8 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family bZIP_1 PF00170.16 KLO04333.1 - 0.28 11.1 5.3 0.64 10.0 3.7 1.7 1 0 0 1 1 1 0 bZIP transcription factor V-SNARE PF05008.10 KLO04333.1 - 4 7.6 8.1 14 5.9 0.5 3.0 2 1 1 3 3 3 0 Vesicle transport v-SNARE protein N-terminus YajC PF02699.10 KLO04334.1 - 6.7 6.4 5.3 22 4.8 3.7 1.8 1 0 0 1 1 1 0 Preprotein translocase subunit DUF4254 PF14063.1 KLO04337.1 - 0.097 12.2 0.0 0.17 11.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4254) Peptidase_C48 PF02902.14 KLO04341.1 - 8.4e-15 54.9 1.6 1.3e-14 54.3 1.1 1.2 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain Selenoprotein_S PF06936.6 KLO04343.1 - 0.11 11.9 5.2 0.18 11.3 3.6 1.2 1 0 0 1 1 1 0 Selenoprotein S (SelS) GWT1 PF06423.7 KLO04345.1 - 0.45 10.6 3.8 0.64 10.1 2.6 1.5 1 1 0 1 1 1 0 GWT1 DEAD PF00270.24 KLO04348.1 - 3.6e-16 59.1 0.0 6.3e-16 58.3 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KLO04348.1 - 3.7e-11 42.7 0.0 3.6e-09 36.3 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 KLO04348.1 - 1.2e-05 25.1 0.0 2.2e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit T4SS-DNA_transf PF02534.9 KLO04348.1 - 8.1e-05 21.3 0.0 0.00012 20.8 0.0 1.1 1 0 0 1 1 1 1 Type IV secretory system Conjugative DNA transfer DUF669 PF05037.8 KLO04348.1 - 0.14 12.0 0.0 0.24 11.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF669) DUF1908 PF08926.6 KLO04349.1 - 0.061 12.0 0.6 0.064 12.0 0.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1908) DnaJ-X PF14308.1 KLO04350.1 - 7.6e-36 123.3 0.0 1.3e-35 122.5 0.0 1.3 1 1 0 1 1 1 1 X-domain of DnaJ-containing Pkinase PF00069.20 KLO04355.1 - 4e-17 62.2 0.0 1.1e-16 60.8 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 KLO04355.1 - 9.3e-13 47.8 0.0 1.5e-12 47.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 KLO04355.1 - 0.024 14.3 0.0 0.077 12.7 0.0 1.8 2 0 0 2 2 2 0 Phosphotransferase enzyme family Med9 PF07544.8 KLO04355.1 - 0.078 12.7 3.0 0.18 11.5 2.1 1.5 1 0 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 DUF3860 PF12976.2 KLO04355.1 - 0.1 12.4 0.2 0.38 10.5 0.1 2.0 2 0 0 2 2 2 0 Domain of Unknown Function with PDB structure (DUF3860) FlaC_arch PF05377.6 KLO04355.1 - 1.6 8.6 5.0 4.2 7.3 3.5 1.6 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) zf-CCHC PF00098.18 KLO04357.1 - 0.014 15.2 3.2 0.026 14.4 2.2 1.5 1 0 0 1 1 1 0 Zinc knuckle eIF3g PF12353.3 KLO04357.1 - 0.5 10.2 4.2 11 5.9 0.0 2.1 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit G U79_P34 PF03064.11 KLO04357.1 - 1.3 8.5 7.0 1.5 8.3 4.8 1.1 1 0 0 1 1 1 0 HSV U79 / HCMV P34 gag_pre-integrs PF13976.1 KLO04358.1 - 0.091 12.4 0.1 0.12 12.0 0.1 1.2 1 0 0 1 1 1 0 GAG-pre-integrase domain Cytochrome_CBB3 PF13442.1 KLO04358.1 - 0.11 12.6 0.0 0.12 12.5 0.0 1.2 1 0 0 1 1 1 0 Cytochrome C oxidase, cbb3-type, subunit III Retrotrans_gag PF03732.12 KLO04360.1 - 2.7e-05 24.1 0.5 4.7e-05 23.3 0.4 1.3 1 0 0 1 1 1 1 Retrotransposon gag protein ApbA_C PF08546.6 KLO04362.1 - 0.13 12.2 0.0 0.18 11.8 0.0 1.1 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA C terminal Peptidase_M2 PF01401.13 KLO04364.1 - 0.056 11.6 0.0 0.066 11.4 0.0 1.1 1 0 0 1 1 1 0 Angiotensin-converting enzyme VirK PF06903.7 KLO04365.1 - 0.0017 18.0 0.2 0.0023 17.6 0.1 1.1 1 0 0 1 1 1 1 VirK protein Rhodopsin_N PF10413.4 KLO04365.1 - 0.098 12.3 1.0 0.19 11.4 0.7 1.4 1 0 0 1 1 1 0 Amino terminal of the G-protein receptor rhodopsin Ku_PK_bind PF08785.6 KLO04365.1 - 0.11 12.3 0.1 0.15 12.0 0.0 1.1 1 0 0 1 1 1 0 Ku C terminal domain like RPA_C PF08784.6 KLO04368.1 - 0.00091 19.6 3.1 0.01 16.2 2.2 2.4 1 1 0 1 1 1 1 Replication protein A C terminal DUF605 PF04652.11 KLO04368.1 - 0.082 12.2 8.9 0.092 12.1 6.1 1.1 1 0 0 1 1 1 0 Vta1 like T5orf172 PF10544.4 KLO04368.1 - 0.12 12.7 0.4 0.65 10.4 0.0 2.0 1 1 1 2 2 2 0 T5orf172 domain Phage_Nu1 PF07471.7 KLO04372.1 - 0.074 12.5 0.0 0.19 11.1 0.0 1.6 2 0 0 2 2 2 0 Phage DNA packaging protein Nu1 Myb_DNA-bind_3 PF12776.2 KLO04373.1 - 0.17 12.5 0.0 0.45 11.1 0.0 1.6 2 0 0 2 2 2 0 Myb/SANT-like DNA-binding domain Chromo PF00385.19 KLO04374.1 - 5.6e-09 35.5 0.1 7.1e-09 35.2 0.0 1.1 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Rhodopsin_N PF10413.4 KLO04375.1 - 0.11 12.2 0.3 0.34 10.6 0.3 1.7 2 0 0 2 2 2 0 Amino terminal of the G-protein receptor rhodopsin DUF3596 PF12167.3 KLO04379.1 - 0.025 14.0 1.1 12 5.5 0.0 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3596) DUF2666 PF10869.3 KLO04379.1 - 0.055 13.4 0.2 0.72 9.8 0.6 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2666) Antigen_Bd37 PF11641.3 KLO04379.1 - 0.08 12.2 0.1 0.15 11.3 0.1 1.4 1 0 0 1 1 1 0 Glycosylphosphatidylinositol-anchored merozoite surface protein Chromo PF00385.19 KLO04381.1 - 1.4e-08 34.3 0.0 1.6e-08 34.1 0.0 1.1 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Herpes_VP19C PF03327.9 KLO04383.1 - 0.062 12.1 0.0 0.11 11.4 0.0 1.3 1 0 0 1 1 1 0 Herpesvirus capsid shell protein VP19C Mito_fiss_reg PF05308.6 KLO04383.1 - 2.5 7.4 8.6 5.7 6.2 5.9 1.5 1 0 0 1 1 1 0 Mitochondrial fission regulator NACHT PF05729.7 KLO04386.1 - 8.5e-06 25.5 0.0 1.9e-05 24.3 0.0 1.7 1 0 0 1 1 1 1 NACHT domain NB-ARC PF00931.17 KLO04386.1 - 7e-05 21.8 0.0 0.00015 20.7 0.0 1.6 1 0 0 1 1 1 1 NB-ARC domain AAA_19 PF13245.1 KLO04386.1 - 0.00038 20.1 0.0 0.00087 18.9 0.0 1.5 1 0 0 1 1 1 1 Part of AAA domain APS_kinase PF01583.15 KLO04386.1 - 0.00044 19.9 0.0 0.00086 18.9 0.0 1.5 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_16 PF13191.1 KLO04386.1 - 0.00045 20.2 0.0 0.0017 18.3 0.0 2.0 2 0 0 2 2 2 1 AAA ATPase domain AAA_17 PF13207.1 KLO04386.1 - 0.00061 20.5 0.1 0.0043 17.8 0.0 2.5 3 0 0 3 3 2 1 AAA domain AAA_18 PF13238.1 KLO04386.1 - 0.00062 20.0 0.0 0.035 14.4 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 KLO04386.1 - 0.0009 19.3 0.0 0.0038 17.3 0.0 2.1 2 0 0 2 2 1 1 AAA domain Parvo_NS1 PF01057.12 KLO04386.1 - 0.0012 17.8 0.0 0.0019 17.1 0.0 1.3 1 0 0 1 1 1 1 Parvovirus non-structural protein NS1 CbiA PF01656.18 KLO04386.1 - 0.0028 17.0 0.3 0.02 14.2 0.2 2.3 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_25 PF13481.1 KLO04386.1 - 0.003 17.0 0.0 0.0064 15.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA PF00004.24 KLO04386.1 - 0.004 17.3 0.0 0.012 15.8 0.0 1.9 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) IstB_IS21 PF01695.12 KLO04386.1 - 0.0052 16.2 0.0 0.012 15.0 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein ABC_tran PF00005.22 KLO04386.1 - 0.0062 16.8 0.0 0.021 15.1 0.0 1.9 1 0 0 1 1 1 1 ABC transporter RuvB_N PF05496.7 KLO04386.1 - 0.0079 15.2 0.0 0.017 14.1 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus ResIII PF04851.10 KLO04386.1 - 0.0094 15.7 0.2 0.033 14.0 0.0 2.1 2 1 0 2 2 1 1 Type III restriction enzyme, res subunit DUF2075 PF09848.4 KLO04386.1 - 0.0098 14.9 0.0 0.015 14.2 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) T2SE PF00437.15 KLO04386.1 - 0.011 14.6 0.0 0.02 13.7 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein Zeta_toxin PF06414.7 KLO04386.1 - 0.012 14.7 0.0 0.024 13.7 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin AAA_14 PF13173.1 KLO04386.1 - 0.019 14.8 0.2 0.13 12.2 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.1 KLO04386.1 - 0.022 14.6 0.1 0.14 12.0 0.0 2.4 3 0 0 3 3 2 0 AAA domain SRP54 PF00448.17 KLO04386.1 - 0.028 13.8 0.0 0.052 12.9 0.0 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain RNA_helicase PF00910.17 KLO04386.1 - 0.034 14.3 0.0 0.088 12.9 0.0 1.7 1 0 0 1 1 1 0 RNA helicase PhoH PF02562.11 KLO04386.1 - 0.035 13.3 0.0 0.069 12.3 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein MobB PF03205.9 KLO04386.1 - 0.038 13.6 0.0 0.083 12.5 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_30 PF13604.1 KLO04386.1 - 0.04 13.4 0.0 0.17 11.4 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.1 KLO04386.1 - 0.047 13.6 0.1 0.13 12.2 0.1 1.8 1 1 0 1 1 1 0 AAA domain KaiC PF06745.8 KLO04386.1 - 0.06 12.4 0.0 0.13 11.3 0.0 1.5 1 0 0 1 1 1 0 KaiC AAA_11 PF13086.1 KLO04386.1 - 0.068 12.7 0.3 0.22 11.0 0.0 2.0 3 0 0 3 3 3 0 AAA domain NTPase_1 PF03266.10 KLO04386.1 - 0.075 12.7 0.0 0.14 11.8 0.0 1.5 1 0 0 1 1 1 0 NTPase ArgK PF03308.11 KLO04386.1 - 0.079 11.7 0.0 0.15 10.7 0.0 1.4 1 0 0 1 1 1 0 ArgK protein AAA_23 PF13476.1 KLO04386.1 - 0.36 11.1 3.6 0.65 10.2 0.0 2.7 2 1 0 2 2 2 0 AAA domain Asp_protease_2 PF13650.1 KLO04391.1 - 2.6e-06 27.8 0.1 5.6e-06 26.7 0.1 1.5 1 0 0 1 1 1 1 Aspartyl protease Herpes_ORF11 PF04797.8 KLO04391.1 - 0.016 13.7 0.1 0.025 13.0 0.1 1.3 1 0 0 1 1 1 0 Herpesvirus dUTPase protein RVP PF00077.15 KLO04391.1 - 0.053 13.4 0.1 0.19 11.6 0.1 2.1 1 1 0 1 1 1 0 Retroviral aspartyl protease Asp_protease PF09668.5 KLO04391.1 - 0.16 11.5 0.0 0.34 10.4 0.0 1.5 2 0 0 2 2 2 0 Aspartyl protease RVT_1 PF00078.22 KLO04394.1 - 0.098 11.9 0.0 0.11 11.7 0.0 1.3 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) WD40 PF00400.27 KLO04396.1 - 3.4e-74 242.3 31.5 6.2e-13 48.0 0.2 7.7 7 0 0 7 7 7 7 WD domain, G-beta repeat eIF2A PF08662.6 KLO04396.1 - 2.6e-07 30.5 0.1 0.0055 16.4 0.0 3.0 1 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A Nbas_N PF15492.1 KLO04396.1 - 0.00012 21.2 3.4 6.6 5.7 0.0 5.1 2 2 3 5 5 5 2 Neuroblastoma-amplified sequence, N terminal PD40 PF07676.7 KLO04396.1 - 0.00089 18.8 0.0 12 5.7 0.0 4.2 4 0 0 4 4 4 1 WD40-like Beta Propeller Repeat DUF3312 PF11768.3 KLO04396.1 - 0.029 12.6 0.0 1.9 6.6 0.0 2.2 1 1 0 2 2 2 0 Protein of unknown function (DUF3312) XLF PF09302.6 KLO04396.1 - 0.053 13.2 0.1 0.14 11.9 0.0 1.7 1 0 0 1 1 1 0 XLF (XRCC4-like factor) Apc4_WD40 PF12894.2 KLO04396.1 - 0.12 11.8 0.0 1.8 8.1 0.0 2.9 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain Nop25 PF09805.4 KLO04397.1 - 0.86 9.6 13.1 19 5.3 9.1 2.4 1 1 0 1 1 1 0 Nucleolar protein 12 (25kDa) SnoaL_2 PF12680.2 KLO04398.1 - 0.0053 17.1 0.0 0.0074 16.6 0.0 1.3 1 0 0 1 1 1 1 SnoaL-like domain ADH_zinc_N PF00107.21 KLO04399.1 - 8.1e-17 60.9 0.0 1.5e-16 60.0 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 KLO04399.1 - 1.1e-07 32.8 0.0 2.6e-07 31.6 0.0 1.7 1 1 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KLO04399.1 - 6.5e-05 22.6 0.4 0.001 18.7 0.1 2.2 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain MULE PF10551.4 KLO04401.1 - 6.3e-10 39.1 0.0 2.2e-09 37.3 0.0 2.1 1 0 0 1 1 1 1 MULE transposase domain Transposase_mut PF00872.13 KLO04401.1 - 0.014 13.9 0.0 0.027 13.0 0.0 1.5 1 1 0 1 1 1 0 Transposase, Mutator family Nucleoplasmin PF03066.10 KLO04402.1 - 0.0015 18.0 1.3 0.0018 17.7 0.9 1.2 1 0 0 1 1 1 1 Nucleoplasmin RXT2_N PF08595.6 KLO04402.1 - 0.0078 16.0 1.4 0.013 15.2 0.9 1.4 1 1 0 1 1 1 1 RXT2-like, N-terminal zf-CCHC_2 PF13696.1 KLO04402.1 - 0.008 15.6 1.0 0.02 14.4 0.7 1.7 1 0 0 1 1 1 1 Zinc knuckle PBP1_TM PF14812.1 KLO04402.1 - 0.0098 16.1 3.3 0.0098 16.1 2.3 1.9 2 0 0 2 2 2 1 Transmembrane domain of transglycosylase PBP1 at N-terminal eIF3g PF12353.3 KLO04402.1 - 0.27 11.1 5.7 0.11 12.4 2.1 1.7 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit G Sigma70_ner PF04546.8 KLO04402.1 - 0.72 9.4 4.5 0.76 9.3 1.6 1.8 2 0 0 2 2 2 0 Sigma-70, non-essential region DUF4611 PF15387.1 KLO04402.1 - 1.4 9.1 12.4 2.1 8.5 5.9 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) zf-CCHC PF00098.18 KLO04402.1 - 2.8 8.0 6.1 5.9 6.9 4.2 1.6 1 1 0 1 1 1 0 Zinc knuckle CENP-B_dimeris PF09026.5 KLO04402.1 - 8.8 6.6 10.2 18 5.6 7.1 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain DUF4409 PF14365.1 KLO04404.1 - 0.016 15.4 0.1 0.046 13.8 0.0 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4409) DDT PF02791.12 KLO04406.1 - 0.15 11.8 0.0 0.37 10.5 0.0 1.6 1 0 0 1 1 1 0 DDT domain zf-CHY PF05495.7 KLO04407.1 - 1.5 9.0 12.3 2.9 8.1 8.5 1.5 1 0 0 1 1 1 0 CHY zinc finger Zn_Tnp_IS1595 PF12760.2 KLO04407.1 - 9.7 6.0 14.7 1.3 8.8 1.8 2.4 1 1 1 2 2 2 0 Transposase zinc-ribbon domain zf-RVT PF13966.1 KLO04410.1 - 0.00014 22.0 0.1 0.00021 21.5 0.0 1.4 1 1 0 1 1 1 1 zinc-binding in reverse transcriptase p450 PF00067.17 KLO04414.1 - 3e-64 217.2 0.0 3.9e-64 216.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 KLO04415.1 - 5.1e-69 232.9 0.0 6.5e-69 232.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 PseudoU_synth_1 PF01416.15 KLO04417.1 - 1.2e-15 57.8 0.0 5.1e-07 30.0 0.0 2.3 2 0 0 2 2 2 2 tRNA pseudouridine synthase PgaD PF13994.1 KLO04420.1 - 0.38 10.2 3.3 1.2 8.6 0.1 2.2 2 0 0 2 2 2 0 PgaD-like protein F-box-like PF12937.2 KLO04422.1 - 2.3e-07 30.4 0.3 6e-07 29.0 0.2 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KLO04422.1 - 3.2e-07 29.8 0.9 3.2e-07 29.8 0.6 2.1 2 0 0 2 2 2 1 F-box domain DUF4331 PF14224.1 KLO04422.1 - 0.074 12.1 0.0 0.12 11.4 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4331) GTSE1_N PF15259.1 KLO04422.1 - 0.17 11.8 2.8 0.54 10.2 1.1 2.2 2 0 0 2 2 2 0 G-2 and S-phase expressed 1 Skp1 PF01466.14 KLO04431.1 - 8.5e-22 76.9 0.4 1.3e-21 76.4 0.3 1.3 1 0 0 1 1 1 1 Skp1 family, dimerisation domain Skp1_POZ PF03931.10 KLO04431.1 - 1.2e-11 44.5 0.0 2.5e-11 43.4 0.0 1.5 1 0 0 1 1 1 1 Skp1 family, tetramerisation domain BTB PF00651.26 KLO04431.1 - 0.019 14.9 0.2 0.34 10.9 0.1 2.3 1 1 0 1 1 1 0 BTB/POZ domain Helicase_C PF00271.26 KLO04434.1 - 1.9e-18 66.0 0.3 1.3e-17 63.4 0.3 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.24 KLO04434.1 - 2.5e-18 66.1 0.0 5.9e-18 64.9 0.0 1.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase ResIII PF04851.10 KLO04434.1 - 0.0076 16.0 0.0 0.027 14.2 0.0 1.9 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit SecA_DEAD PF07517.9 KLO04434.1 - 0.051 12.8 0.0 0.083 12.1 0.0 1.3 1 0 0 1 1 1 0 SecA DEAD-like domain Radical_SAM PF04055.16 KLO04434.1 - 0.067 13.3 0.0 5.3 7.1 0.0 3.0 2 1 0 3 3 3 0 Radical SAM superfamily NAD_binding_9 PF13454.1 KLO04434.1 - 0.091 12.5 0.0 0.28 10.9 0.0 1.7 1 1 1 2 2 2 0 FAD-NAD(P)-binding DUF4106 PF13388.1 KLO04435.1 - 0.055 12.4 0.0 0.065 12.1 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4106) GSH_synth_ATP PF03917.12 KLO04436.1 - 2.2e-77 260.1 0.0 2.6e-77 259.9 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic glutathione synthase, ATP binding domain GSH_synthase PF03199.10 KLO04436.1 - 7.6e-35 119.1 0.0 1.2e-34 118.5 0.0 1.3 1 0 0 1 1 1 1 Eukaryotic glutathione synthase Fe-S_biosyn PF01521.15 KLO04437.1 - 1.6e-12 47.3 0.0 2.2e-12 46.8 0.0 1.2 1 0 0 1 1 1 1 Iron-sulphur cluster biosynthesis DDE_1 PF03184.14 KLO04438.1 - 3.3e-16 59.0 0.1 1e-12 47.6 0.0 2.9 1 1 0 1 1 1 1 DDE superfamily endonuclease DDE_3 PF13358.1 KLO04438.1 - 0.039 13.6 0.0 0.18 11.5 0.0 2.0 1 1 0 1 1 1 0 DDE superfamily endonuclease Spt5-NGN PF03439.8 KLO04441.1 - 1.7e-07 30.8 0.0 3.2e-07 30.0 0.0 1.5 1 0 0 1 1 1 1 Early transcription elongation factor of RNA pol II, NGN section KOW PF00467.24 KLO04441.1 - 0.00025 20.6 26.5 0.024 14.3 0.0 5.2 7 0 0 7 7 7 3 KOW motif Tox-WTIP PF15654.1 KLO04443.1 - 0.12 11.9 0.3 0.27 10.9 0.2 1.5 1 0 0 1 1 1 0 Toxin with a conserved tryptophan and TIP tripeptide motif DUF4551 PF15087.1 KLO04444.1 - 0.31 9.3 1.8 0.34 9.2 1.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) ImmE5 PF11480.3 KLO04445.1 - 0.035 13.9 0.0 0.057 13.2 0.0 1.3 1 0 0 1 1 1 0 Colicin-E5 Imm protein Lin0512_fam PF09585.5 KLO04445.1 - 0.08 12.5 0.0 0.098 12.2 0.0 1.1 1 0 0 1 1 1 0 Conserved hypothetical protein (Lin0512_fam) PHA_synth_III_E PF09712.5 KLO04446.1 - 0.078 12.3 0.3 0.11 11.9 0.2 1.3 1 0 0 1 1 1 0 Poly(R)-hydroxyalkanoic acid synthase subunit (PHA_synth_III_E) Transposase_21 PF02992.9 KLO04449.1 - 1.2e-09 37.5 0.0 1.4e-09 37.3 0.0 1.2 1 0 0 1 1 1 1 Transposase family tnp2 Cytochrome_CBB3 PF13442.1 KLO04449.1 - 0.061 13.4 0.0 0.11 12.6 0.0 1.5 1 0 0 1 1 1 0 Cytochrome C oxidase, cbb3-type, subunit III zf-A20 PF01754.11 KLO04449.1 - 1.7 8.2 4.8 0.53 9.9 0.8 2.0 2 0 0 2 2 2 0 A20-like zinc finger DUF4218 PF13960.1 KLO04450.1 - 1.3e-06 27.8 0.1 2e-06 27.2 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4218) Kua-UEV1_localn PF10520.4 KLO04450.1 - 0.06 13.0 0.1 0.075 12.6 0.1 1.1 1 0 0 1 1 1 0 Kua-ubiquitin conjugating enzyme hybrid localisation domain TOH_N PF12549.3 KLO04453.1 - 0.26 10.9 1.3 0.59 9.7 0.9 1.7 1 0 0 1 1 1 0 Tyrosine hydroxylase N terminal F-box-like PF12937.2 KLO04456.1 - 0.085 12.6 0.1 0.2 11.4 0.0 1.7 1 0 0 1 1 1 0 F-box-like zf-C2H2 PF00096.21 KLO04459.1 - 0.05 13.9 0.2 0.19 12.1 0.2 2.1 1 0 0 1 1 1 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KLO04459.1 - 0.81 10.1 7.1 0.36 11.2 0.3 3.6 3 0 0 3 3 3 0 C2H2-type zinc finger TCTP PF00838.12 KLO04460.1 - 0.16 11.9 0.3 0.51 10.3 0.0 1.8 1 1 1 2 2 2 0 Translationally controlled tumour protein MADF_DNA_bdg PF10545.4 KLO04463.1 - 0.2 11.8 6.6 0.58 10.3 0.0 2.5 2 0 0 2 2 2 0 Alcohol dehydrogenase transcription factor Myb/SANT-like Adaptin_N PF01602.15 KLO04465.1 - 1e-09 37.3 0.1 1.2e-09 37.0 0.1 1.0 1 0 0 1 1 1 1 Adaptin N terminal region zf-MYND PF01753.13 KLO04476.1 - 1.4e-05 24.8 9.3 2.7e-05 23.9 6.4 1.5 1 0 0 1 1 1 1 MYND finger DUF1689 PF07954.6 KLO04478.1 - 0.078 12.8 0.1 0.078 12.8 0.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1689) KbaA PF14089.1 KLO04478.1 - 0.08 12.4 1.0 0.092 12.2 0.7 1.0 1 0 0 1 1 1 0 KinB-signalling pathway activation in sporulation DUF3767 PF12597.3 KLO04478.1 - 0.15 11.7 0.0 0.15 11.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3767) DUF3035 PF11233.3 KLO04480.1 - 0.055 13.5 2.4 0.1 12.6 1.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3035) Kisspeptin PF15152.1 KLO04480.1 - 1.8 9.2 6.0 1.7 9.3 1.0 2.2 1 1 1 2 2 2 0 Kisspeptin HTH_Tnp_ISL3 PF13542.1 KLO04481.1 - 0.13 11.4 2.9 0.69 9.1 0.0 3.3 5 0 0 5 5 5 0 Helix-turn-helix domain of transposase family ISL3 p12I PF12233.3 KLO04482.1 - 0.051 13.8 0.1 0.051 13.8 0.0 1.1 1 0 0 1 1 1 0 Human adult T cell leukemia/lymphoma virus protein RS4NT PF08071.7 KLO04483.1 - 1.1e-21 76.3 4.0 1.6e-21 75.8 2.8 1.2 1 0 0 1 1 1 1 RS4NT (NUC023) domain S4 PF01479.20 KLO04483.1 - 6.7e-05 22.2 0.0 8.7e-05 21.8 0.0 1.2 1 0 0 1 1 1 1 S4 domain RVT_1 PF00078.22 KLO04484.1 - 0.00087 18.7 0.0 0.0017 17.7 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_1 PF00078.22 KLO04485.1 - 1.1e-07 31.4 0.0 2e-07 30.5 0.0 1.4 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RNase_H PF00075.19 KLO04486.1 - 1.5e-23 83.5 0.0 1.7e-23 83.3 0.0 1.0 1 0 0 1 1 1 1 RNase H WXG100 PF06013.7 KLO04487.1 - 0.023 14.6 0.3 0.023 14.6 0.2 3.4 3 1 1 4 4 4 0 Proteins of 100 residues with WXG DUF883 PF05957.8 KLO04487.1 - 0.14 12.5 4.7 0.7 10.3 0.0 2.5 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF883) FUSC PF04632.7 KLO04487.1 - 0.51 8.7 5.5 0.82 8.0 3.8 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family Mnd1 PF03962.10 KLO04487.1 - 1.1 8.8 3.8 2 8.0 2.6 1.4 1 0 0 1 1 1 0 Mnd1 family DUF3584 PF12128.3 KLO04487.1 - 1.4 6.1 9.8 2.1 5.5 6.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) WD40 PF00400.27 KLO04488.1 - 1.2e-64 212.0 27.9 4.6e-11 42.1 0.1 7.8 7 0 0 7 7 7 7 WD domain, G-beta repeat AAA_16 PF13191.1 KLO04488.1 - 7.4e-11 42.3 0.3 8.2e-05 22.6 0.0 3.9 3 0 0 3 3 3 2 AAA ATPase domain NACHT PF05729.7 KLO04488.1 - 8.5e-10 38.5 1.4 0.0026 17.4 0.0 4.4 2 2 0 2 2 2 2 NACHT domain AAA_22 PF13401.1 KLO04488.1 - 2.1e-09 37.5 0.0 0.0042 17.2 0.0 3.3 3 0 0 3 3 2 2 AAA domain AAA PF00004.24 KLO04488.1 - 5.4e-09 36.3 0.0 0.005 17.0 0.0 3.4 2 1 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 KLO04488.1 - 1.5e-06 29.0 0.2 0.12 13.2 0.0 3.8 3 0 0 3 3 2 2 AAA domain Zeta_toxin PF06414.7 KLO04488.1 - 4.9e-06 25.7 0.0 0.035 13.1 0.0 2.5 2 0 0 2 2 2 2 Zeta toxin PD40 PF07676.7 KLO04488.1 - 8.5e-06 25.3 0.1 14 5.5 0.0 5.0 5 0 0 5 5 4 0 WD40-like Beta Propeller Repeat AAA_19 PF13245.1 KLO04488.1 - 1e-05 25.2 0.0 0.16 11.7 0.0 3.0 3 0 0 3 3 2 2 Part of AAA domain NB-ARC PF00931.17 KLO04488.1 - 1.5e-05 24.0 0.0 0.0083 15.0 0.0 3.0 2 1 0 2 2 2 1 NB-ARC domain RNA_helicase PF00910.17 KLO04488.1 - 2e-05 24.6 0.0 0.7 10.0 0.0 3.6 3 0 0 3 3 3 2 RNA helicase AAA_18 PF13238.1 KLO04488.1 - 3.7e-05 24.0 0.0 0.47 10.7 0.0 2.9 2 1 0 2 2 2 2 AAA domain APS_kinase PF01583.15 KLO04488.1 - 4.2e-05 23.2 0.0 0.23 11.1 0.0 2.4 2 0 0 2 2 2 2 Adenylylsulphate kinase AAA_25 PF13481.1 KLO04488.1 - 0.0001 21.7 0.2 0.46 9.8 0.1 3.0 2 1 0 2 2 2 2 AAA domain DUF2075 PF09848.4 KLO04488.1 - 0.00016 20.7 0.0 0.37 9.6 0.0 2.3 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2075) AAA_33 PF13671.1 KLO04488.1 - 0.00022 21.1 0.0 0.56 10.0 0.0 2.8 2 0 0 2 2 2 2 AAA domain KAP_NTPase PF07693.9 KLO04488.1 - 0.0006 18.8 0.0 0.29 10.0 0.0 3.8 4 0 0 4 4 4 1 KAP family P-loop domain Gmad1 PF10647.4 KLO04488.1 - 0.00072 19.0 0.6 2.2 7.6 0.1 3.4 2 1 1 3 3 3 1 Lipoprotein LpqB beta-propeller domain AAA_14 PF13173.1 KLO04488.1 - 0.0045 16.8 0.0 4 7.3 0.0 3.6 2 1 0 2 2 2 0 AAA domain Arch_ATPase PF01637.13 KLO04488.1 - 0.0046 16.6 0.0 0.19 11.4 0.0 3.4 4 0 0 4 4 2 1 Archaeal ATPase Parvo_NS1 PF01057.12 KLO04488.1 - 0.0061 15.4 0.0 0.19 10.5 0.0 2.2 2 0 0 2 2 2 1 Parvovirus non-structural protein NS1 AAA_5 PF07728.9 KLO04488.1 - 0.0065 16.1 0.0 1.2 8.8 0.0 2.9 3 0 0 3 3 2 1 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.12 KLO04488.1 - 0.0069 15.8 0.0 1.1 8.6 0.0 2.8 3 0 0 3 3 2 1 IstB-like ATP binding protein AAA_28 PF13521.1 KLO04488.1 - 0.0095 15.9 0.0 6.7 6.6 0.0 2.7 2 0 0 2 2 2 0 AAA domain Nbas_N PF15492.1 KLO04488.1 - 0.011 14.8 1.4 4.5 6.2 0.0 4.0 3 2 1 4 4 4 0 Neuroblastoma-amplified sequence, N terminal ABC_tran PF00005.22 KLO04488.1 - 0.019 15.2 0.0 2.1 8.6 0.0 2.9 3 0 0 3 3 2 0 ABC transporter AAA_30 PF13604.1 KLO04488.1 - 0.019 14.5 0.1 0.53 9.8 0.0 2.4 2 0 0 2 2 2 0 AAA domain ArgK PF03308.11 KLO04488.1 - 0.021 13.6 0.0 0.52 9.0 0.0 2.3 2 0 0 2 2 2 0 ArgK protein Mg_chelatase PF01078.16 KLO04488.1 - 0.021 13.9 0.0 4.6 6.3 0.0 2.4 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_PrkA PF08298.6 KLO04488.1 - 0.023 13.4 0.0 0.084 11.5 0.0 1.8 2 0 0 2 2 2 0 PrkA AAA domain ResIII PF04851.10 KLO04488.1 - 0.028 14.2 0.0 0.46 10.2 0.0 2.3 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit MobB PF03205.9 KLO04488.1 - 0.05 13.3 0.0 2.1 8.0 0.0 2.5 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B TrwB_AAD_bind PF10412.4 KLO04488.1 - 0.058 12.0 0.0 1.5 7.3 0.0 2.6 3 0 0 3 3 3 0 Type IV secretion-system coupling protein DNA-binding domain Sigma54_activ_2 PF14532.1 KLO04488.1 - 0.079 13.0 0.1 22 5.0 0.0 3.3 4 0 0 4 4 3 0 Sigma-54 interaction domain AAA_11 PF13086.1 KLO04488.1 - 0.082 12.4 0.0 11 5.4 0.0 2.4 2 0 0 2 2 2 0 AAA domain Torsin PF06309.6 KLO04488.1 - 0.09 12.6 0.0 18 5.2 0.0 2.5 2 0 0 2 2 2 0 Torsin KTI12 PF08433.5 KLO04488.1 - 0.14 11.3 0.0 15 4.7 0.0 2.4 2 0 0 2 2 2 0 Chromatin associated protein KTI12 AAA_10 PF12846.2 KLO04488.1 - 0.16 11.3 0.4 20 4.4 0.2 3.0 2 1 0 2 2 2 0 AAA-like domain TIP49 PF06068.8 KLO04488.1 - 0.25 10.0 0.1 1.4 7.5 0.0 2.0 2 0 0 2 2 2 0 TIP49 C-terminus Cyclin PF08613.6 KLO04490.1 - 2.6e-09 37.6 0.4 1.6e-06 28.5 0.0 2.4 2 1 0 2 2 2 2 Cyclin Cyclin_N PF00134.18 KLO04490.1 - 0.0069 15.9 0.0 0.013 15.0 0.0 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain zf-MYND PF01753.13 KLO04494.1 - 1.5e-06 27.9 9.4 3.8e-06 26.6 6.5 1.7 1 0 0 1 1 1 1 MYND finger SAP PF02037.22 KLO04496.1 - 0.13 11.7 0.0 0.23 11.0 0.0 1.3 1 0 0 1 1 1 0 SAP domain Amnionless PF14828.1 KLO04502.1 - 0.015 13.8 0.0 0.021 13.3 0.0 1.1 1 0 0 1 1 1 0 Amnionless Plasmodium_Vir PF05795.6 KLO04502.1 - 0.088 12.0 0.0 0.091 11.9 0.0 1.2 1 0 0 1 1 1 0 Plasmodium vivax Vir protein NSP2-B_epitope PF14757.1 KLO04503.1 - 0.055 12.9 0.3 0.079 12.4 0.2 1.2 1 0 0 1 1 1 0 Immunogenic region of nsp2 protein of arterivirus polyprotein Tenui_NCP PF04876.7 KLO04504.1 - 0.00045 19.7 0.1 0.00066 19.2 0.1 1.1 1 0 0 1 1 1 1 Tenuivirus major non-capsid protein Acetyltransf_6 PF13480.1 KLO04505.1 - 0.18 11.7 0.1 1.4 8.8 0.0 2.3 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain F-box-like PF12937.2 KLO04506.1 - 2.9e-05 23.6 3.1 2.9e-05 23.6 2.2 2.4 2 1 0 2 2 2 1 F-box-like F-box PF00646.28 KLO04506.1 - 0.0026 17.3 4.5 0.0049 16.4 1.3 2.7 2 1 0 2 2 2 1 F-box domain F-box-like_2 PF13013.1 KLO04506.1 - 0.28 10.9 2.8 0.19 11.4 0.4 1.9 2 1 0 2 2 2 0 F-box-like domain Asp_protease_2 PF13650.1 KLO04509.1 - 4.8e-05 23.7 0.0 5e-05 23.7 0.0 1.2 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.6 KLO04509.1 - 5.8e-05 23.0 0.0 7.1e-05 22.7 0.0 1.1 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.1 KLO04509.1 - 0.00076 19.2 0.0 0.001 18.8 0.0 1.4 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Cauli_VI PF01693.11 KLO04513.1 - 9.9e-10 38.2 0.2 1.6e-09 37.6 0.2 1.2 1 0 0 1 1 1 1 Caulimovirus viroplasmin Oxidored-like PF09791.4 KLO04513.1 - 0.0013 18.1 0.0 0.0032 16.8 0.0 1.7 1 0 0 1 1 1 1 Oxidoreductase-like protein, N-terminal zf-B_box PF00643.19 KLO04514.1 - 0.54 10.1 7.1 1.6 8.6 5.0 1.8 1 0 0 1 1 1 0 B-box zinc finger Sars6 PF12133.3 KLO04517.1 - 0.16 11.6 0.8 0.43 10.2 0.5 1.7 1 1 0 1 1 1 0 Open reading frame 6 from SARS coronavirus ING PF12998.2 KLO04518.1 - 1.3 9.3 3.9 26 5.1 0.1 2.3 2 0 0 2 2 2 0 Inhibitor of growth proteins N-terminal histone-binding DUF721 PF05258.7 KLO04520.1 - 0.17 12.0 1.1 0.46 10.7 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF721) ThiW PF09512.5 KLO04521.1 - 0.12 12.1 0.1 0.19 11.5 0.1 1.3 1 0 0 1 1 1 0 Thiamine-precursor transporter protein (ThiW) CNP1 PF08750.6 KLO04523.1 - 0.05 13.2 0.2 0.069 12.8 0.1 1.2 1 0 0 1 1 1 0 CNP1-like family Phytochelatin PF05023.9 KLO04523.1 - 0.11 11.3 0.1 0.16 10.8 0.1 1.3 1 1 0 1 1 1 0 Phytochelatin synthase DAO PF01266.19 KLO04525.1 - 2e-09 36.8 0.1 2.8e-09 36.3 0.1 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_oxidored PF12831.2 KLO04525.1 - 1.8e-05 24.0 1.8 2.6e-05 23.5 1.2 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 KLO04525.1 - 2.4e-05 24.3 0.0 2.7e-05 24.1 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 KLO04525.1 - 0.00021 20.2 0.3 0.00026 19.9 0.2 1.1 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.22 KLO04525.1 - 0.00039 20.7 0.1 0.00062 20.1 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KLO04525.1 - 0.0025 17.7 0.1 0.0043 17.0 0.1 1.4 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain 3HCDH_N PF02737.13 KLO04525.1 - 0.0028 17.3 0.0 0.0038 16.9 0.0 1.2 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain HI0933_like PF03486.9 KLO04525.1 - 0.0035 15.8 0.3 0.0047 15.4 0.2 1.1 1 0 0 1 1 1 1 HI0933-like protein GIDA PF01134.17 KLO04525.1 - 0.012 14.4 0.3 0.016 14.0 0.2 1.1 1 0 0 1 1 1 0 Glucose inhibited division protein A Thi4 PF01946.12 KLO04525.1 - 0.018 14.1 0.1 0.026 13.6 0.0 1.1 1 0 0 1 1 1 0 Thi4 family Lycopene_cycl PF05834.7 KLO04525.1 - 0.051 12.4 0.7 0.07 12.0 0.5 1.1 1 0 0 1 1 1 0 Lycopene cyclase protein Pyr_redox_3 PF13738.1 KLO04525.1 - 0.076 13.0 0.1 0.11 12.5 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase GDI PF00996.13 KLO04525.1 - 0.17 10.1 0.0 0.2 9.9 0.0 1.1 1 0 0 1 1 1 0 GDP dissociation inhibitor NAD_binding_10 PF13460.1 KLO04525.1 - 0.18 11.7 0.6 0.35 10.8 0.2 1.6 2 0 0 2 2 2 0 NADH(P)-binding Phasin PF05597.6 KLO04527.1 - 0.0039 16.9 0.3 0.007 16.1 0.2 1.3 1 0 0 1 1 1 1 Poly(hydroxyalcanoate) granule associated protein (phasin) Pex19 PF04614.7 KLO04527.1 - 0.037 13.6 1.2 0.064 12.8 0.8 1.3 1 0 0 1 1 1 0 Pex19 protein family EDR1 PF14381.1 KLO04527.1 - 0.18 11.3 0.2 0.29 10.6 0.1 1.2 1 0 0 1 1 1 0 Ethylene-responsive protein kinase Le-CTR1 Erf4 PF10256.4 KLO04530.1 - 0.0016 18.3 0.0 0.002 17.9 0.0 1.2 1 0 0 1 1 1 1 Golgin subfamily A member 7/ERF4 family TMCO5 PF14992.1 KLO04535.1 - 0.0036 16.4 0.1 0.0064 15.6 0.1 1.5 1 0 0 1 1 1 1 TMCO5 family Tankyrase_bdg_C PF15327.1 KLO04535.1 - 0.032 14.4 1.2 0.032 14.4 0.8 1.6 2 0 0 2 2 2 0 Tankyrase binding protein C terminal domain CortBP2 PF09727.4 KLO04535.1 - 0.036 13.5 1.4 0.055 12.9 0.8 1.4 1 1 0 1 1 1 0 Cortactin-binding protein-2 DUF3983 PF13137.1 KLO04535.1 - 2.7 7.7 6.7 25 4.6 0.9 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF3983) DUF1263 PF06882.7 KLO04537.1 - 0.058 13.0 0.0 0.13 11.8 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1263) Levi_coat PF01819.12 KLO04539.1 - 0.025 14.1 0.6 0.033 13.7 0.4 1.1 1 0 0 1 1 1 0 Levivirus coat protein MAGE_N PF12440.3 KLO04543.1 - 0.76 10.1 6.4 0.27 11.5 2.2 1.8 2 0 0 2 2 2 0 Melanoma associated antigen family N terminal WD40 PF00400.27 KLO04544.1 - 3.1e-26 90.2 9.8 1.3e-11 43.9 0.1 4.0 4 0 0 4 4 4 3 WD domain, G-beta repeat B_lectin PF01453.19 KLO04544.1 - 0.0025 17.7 0.1 0.0047 16.8 0.1 1.5 1 0 0 1 1 1 1 D-mannose binding lectin Nucleoporin_N PF08801.6 KLO04544.1 - 0.011 14.5 0.1 0.015 14.0 0.1 1.2 1 0 0 1 1 1 0 Nup133 N terminal like Nbas_N PF15492.1 KLO04544.1 - 0.021 13.9 0.3 2.8 6.9 0.0 2.2 1 1 1 2 2 2 0 Neuroblastoma-amplified sequence, N terminal SGL PF08450.7 KLO04544.1 - 0.026 13.9 0.0 0.037 13.4 0.0 1.2 1 0 0 1 1 1 0 SMP-30/Gluconolaconase/LRE-like region Apc4_WD40 PF12894.2 KLO04544.1 - 0.03 13.8 0.0 0.36 10.3 0.0 2.2 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain DUF2945 PF11160.3 KLO04544.1 - 0.075 12.8 0.1 0.15 11.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2945) DUF1772 PF08592.6 KLO04546.1 - 0.082 12.6 0.1 0.1 12.3 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1772) RVP PF00077.15 KLO04548.1 - 0.00064 19.6 0.1 0.0017 18.2 0.0 1.7 1 1 1 2 2 2 1 Retroviral aspartyl protease UBA_4 PF14555.1 KLO04548.1 - 0.11 12.0 0.0 0.6 9.6 0.0 2.0 2 0 0 2 2 2 0 UBA-like domain Cupin_6 PF12852.2 KLO04548.1 - 0.11 12.0 0.0 0.12 11.9 0.0 1.1 1 0 0 1 1 1 0 Cupin FliT PF05400.8 KLO04550.1 - 0.097 13.0 0.6 0.097 13.0 0.4 2.2 3 0 0 3 3 3 0 Flagellar protein FliT WD40 PF00400.27 KLO04551.1 - 7.8e-12 44.6 1.8 1.3e-06 28.0 0.2 5.2 6 0 0 6 6 6 2 WD domain, G-beta repeat DUF808 PF05661.7 KLO04551.1 - 0.038 12.8 0.1 0.063 12.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF808) HTH_Tnp_Tc5 PF03221.11 KLO04553.1 - 5.1e-08 32.6 0.0 5.5e-08 32.4 0.0 1.1 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain DDE_1 PF03184.14 KLO04554.1 - 2e-38 131.7 0.0 2.3e-38 131.5 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_3 PF13358.1 KLO04554.1 - 2e-08 34.1 0.0 3.3e-08 33.4 0.0 1.4 1 1 0 1 1 1 1 DDE superfamily endonuclease DUF3545 PF12065.3 KLO04555.1 - 0.35 10.6 2.7 0.85 9.4 1.8 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3545) BTB PF00651.26 KLO04558.1 - 8.1e-05 22.5 0.0 0.00021 21.2 0.0 1.6 1 0 0 1 1 1 1 BTB/POZ domain IN_DBD_C PF00552.16 KLO04558.1 - 0.047 13.1 0.0 0.14 11.6 0.0 1.7 2 0 0 2 2 2 0 Integrase DNA binding domain DUF4329 PF14220.1 KLO04559.1 - 6.3e-06 26.1 0.0 8.4e-06 25.7 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4329) Prok-JAB PF14464.1 KLO04559.1 - 0.0068 15.9 0.0 0.0081 15.7 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain DUF4329 PF14220.1 KLO04560.1 - 0.00029 20.7 0.0 0.0004 20.3 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4329) Prok-JAB PF14464.1 KLO04560.1 - 0.01 15.3 0.0 0.013 15.0 0.0 1.3 1 0 0 1 1 1 0 Prokaryotic homologs of the JAB domain DUF4329 PF14220.1 KLO04561.1 - 3.3e-05 23.8 0.0 4.9e-05 23.2 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4329) Prok-JAB PF14464.1 KLO04561.1 - 0.0021 17.6 0.0 0.0029 17.1 0.0 1.4 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain Pkinase PF00069.20 KLO04563.1 - 1.7e-30 106.0 0.0 2.1e-30 105.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KLO04563.1 - 1.2e-28 99.9 0.0 1.6e-28 99.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase CENP-U PF13097.1 KLO04565.1 - 0.0034 17.3 1.2 0.0042 17.0 0.8 1.3 1 1 0 1 1 1 1 CENP-A nucleosome associated complex (NAC) subunit Mucin PF01456.12 KLO04565.1 - 0.13 11.9 4.8 0.18 11.5 3.3 1.2 1 0 0 1 1 1 0 Mucin-like glycoprotein p450 PF00067.17 KLO04572.1 - 4.3e-53 180.4 0.0 9.7e-53 179.3 0.0 1.5 1 1 0 1 1 1 1 Cytochrome P450 Fer4_21 PF14697.1 KLO04573.1 - 7.1 6.5 9.6 3.4 7.6 4.6 2.0 1 1 0 1 1 1 0 4Fe-4S dicluster domain Fer4_6 PF12837.2 KLO04573.1 - 9.8 6.2 7.8 8.7 6.3 1.7 2.4 2 1 0 2 2 2 0 4Fe-4S binding domain APH PF01636.18 KLO04574.1 - 6.2e-09 35.9 0.0 8.7e-09 35.4 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Dpy-30 PF05186.8 KLO04577.1 - 0.017 14.5 0.2 0.038 13.4 0.0 1.6 2 0 0 2 2 2 0 Dpy-30 motif CENP-U PF13097.1 KLO04579.1 - 0.001 19.0 0.1 0.0013 18.6 0.0 1.2 1 0 0 1 1 1 1 CENP-A nucleosome associated complex (NAC) subunit Pacs-1 PF10254.4 KLO04579.1 - 0.027 13.1 0.0 0.035 12.7 0.0 1.1 1 0 0 1 1 1 0 PACS-1 cytosolic sorting protein Pkinase PF00069.20 KLO04581.1 - 1.3e-29 103.1 0.0 1.4e-29 103.0 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KLO04581.1 - 1.3e-26 93.2 0.0 1.6e-26 92.9 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 KLO04581.1 - 0.02 14.6 0.0 0.043 13.5 0.0 1.4 1 1 0 1 1 1 0 Phosphotransferase enzyme family GMAP PF06540.6 KLO04581.1 - 0.081 12.6 0.0 0.13 12.0 0.0 1.3 1 0 0 1 1 1 0 Galanin message associated peptide (GMAP) RVT_1 PF00078.22 KLO04582.1 - 4.5e-06 26.1 0.0 1e-05 25.0 0.0 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DDE_3 PF13358.1 KLO04586.1 - 2.1e-09 37.2 0.0 2.5e-09 37.0 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_3 PF13358.1 KLO04587.1 - 1.2e-10 41.3 0.0 1.3e-10 41.2 0.0 1.0 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_29 PF13551.1 KLO04588.1 - 1.5e-13 50.8 0.8 1.8e-13 50.6 0.5 1.1 1 0 0 1 1 1 1 Winged helix-turn helix HTH_23 PF13384.1 KLO04588.1 - 6e-10 38.4 0.7 2.7e-08 33.1 0.0 2.3 2 0 0 2 2 2 1 Homeodomain-like domain HTH_32 PF13565.1 KLO04588.1 - 9.9e-10 39.0 0.8 1.4e-09 38.5 0.6 1.3 1 0 0 1 1 1 1 Homeodomain-like domain HTH_Tnp_Tc3_2 PF01498.13 KLO04588.1 - 5.9e-06 26.2 0.2 8.3e-05 22.5 0.0 2.2 2 0 0 2 2 2 1 Transposase HTH_33 PF13592.1 KLO04588.1 - 5.1e-05 22.7 0.1 0.0001 21.7 0.0 1.5 2 0 0 2 2 1 1 Winged helix-turn helix HTH_IclR PF09339.5 KLO04588.1 - 0.00017 21.1 0.0 0.00044 19.7 0.0 1.8 1 0 0 1 1 1 1 IclR helix-turn-helix domain Sigma70_r4_2 PF08281.7 KLO04588.1 - 0.0004 19.7 0.1 0.013 14.9 0.0 2.3 2 0 0 2 2 2 1 Sigma-70, region 4 HTH_Tnp_IS630 PF01710.11 KLO04588.1 - 0.00041 20.0 0.0 0.00066 19.3 0.0 1.3 1 1 0 1 1 1 1 Transposase HTH_28 PF13518.1 KLO04588.1 - 0.00087 19.2 0.7 0.0028 17.5 0.1 2.0 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_11 PF08279.7 KLO04588.1 - 0.0022 17.5 0.0 0.53 9.9 0.0 2.3 2 0 0 2 2 2 1 HTH domain HTH_Tnp_ISL3 PF13542.1 KLO04588.1 - 0.003 16.6 1.9 0.45 9.7 0.0 2.3 2 0 0 2 2 2 2 Helix-turn-helix domain of transposase family ISL3 TrmB PF01978.14 KLO04588.1 - 0.0039 16.8 0.0 0.012 15.3 0.0 1.8 2 0 0 2 2 2 1 Sugar-specific transcriptional regulator TrmB Rrf2 PF02082.15 KLO04588.1 - 0.0083 16.2 0.0 0.014 15.4 0.0 1.5 1 0 0 1 1 1 1 Transcriptional regulator HTH_Crp_2 PF13545.1 KLO04588.1 - 0.019 14.7 0.0 0.037 13.8 0.0 1.5 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain DUF134 PF02001.11 KLO04588.1 - 0.023 14.5 0.2 1.9 8.4 0.0 2.3 1 1 1 2 2 2 0 Protein of unknown function DUF134 HTH_7 PF02796.10 KLO04588.1 - 0.041 13.7 0.2 0.73 9.7 0.0 2.6 3 0 0 3 3 3 0 Helix-turn-helix domain of resolvase MarR_2 PF12802.2 KLO04588.1 - 0.046 13.3 0.2 0.21 11.2 0.0 2.0 2 0 0 2 2 2 0 MarR family HTH_21 PF13276.1 KLO04588.1 - 0.05 13.6 0.5 0.48 10.4 0.1 2.4 2 1 0 2 2 2 0 HTH-like domain Sigma70_r4 PF04545.11 KLO04588.1 - 0.076 12.3 0.0 0.5 9.7 0.0 2.1 2 0 0 2 2 2 0 Sigma-70, region 4 HTH_24 PF13412.1 KLO04588.1 - 0.085 12.2 0.1 3.4 7.1 0.0 2.3 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding HTH_Tnp_4 PF13613.1 KLO04588.1 - 0.14 11.7 0.2 15 5.2 0.0 2.5 2 0 0 2 2 2 0 Helix-turn-helix of DDE superfamily endonuclease HTH_17 PF12728.2 KLO04588.1 - 0.16 12.2 0.3 1.7 8.9 0.0 2.3 2 1 0 2 2 2 0 Helix-turn-helix domain Syntaxin_2 PF14523.1 KLO04589.1 - 0.031 14.3 2.1 2.2 8.3 0.2 2.8 2 0 0 2 2 2 0 Syntaxin-like protein Spc7 PF08317.6 KLO04589.1 - 0.062 11.9 3.0 0.4 9.3 0.2 2.3 2 0 0 2 2 2 0 Spc7 kinetochore protein WD40 PF00400.27 KLO04592.1 - 2.5e-12 46.1 3.1 1.2e-06 28.1 0.0 4.6 5 0 0 5 5 5 4 WD domain, G-beta repeat DUF663 PF04950.7 KLO04593.1 - 2.7e-92 308.9 0.0 2.7e-92 308.9 0.0 1.8 2 0 0 2 2 1 1 Protein of unknown function (DUF663) AARP2CN PF08142.7 KLO04593.1 - 3.4e-27 93.7 0.0 1.1e-26 92.1 0.0 1.9 2 0 0 2 2 1 1 AARP2CN (NUC121) domain GTP_EFTU PF00009.22 KLO04593.1 - 2.8e-05 23.6 3.5 0.0029 17.0 0.0 3.1 2 1 1 3 3 3 1 Elongation factor Tu GTP binding domain AAA_16 PF13191.1 KLO04593.1 - 6.1e-05 23.0 0.6 0.00022 21.2 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain AAA_17 PF13207.1 KLO04593.1 - 7.1e-05 23.6 0.0 7.1e-05 23.6 0.0 3.7 4 0 0 4 4 3 1 AAA domain AAA_22 PF13401.1 KLO04593.1 - 7.4e-05 22.9 0.0 0.00022 21.3 0.0 1.8 1 0 0 1 1 1 1 AAA domain MobB PF03205.9 KLO04593.1 - 7.8e-05 22.3 0.0 0.00024 20.8 0.0 1.9 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B ABC_tran PF00005.22 KLO04593.1 - 0.00023 21.4 1.5 0.00044 20.5 0.0 2.2 2 0 0 2 2 1 1 ABC transporter DUF258 PF03193.11 KLO04593.1 - 0.00027 20.1 0.0 0.00054 19.1 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Miro PF08477.8 KLO04593.1 - 0.0013 19.1 0.0 0.0039 17.6 0.0 1.7 1 0 0 1 1 1 1 Miro-like protein AAA_33 PF13671.1 KLO04593.1 - 0.0022 17.9 1.9 0.0025 17.7 0.0 2.1 2 0 0 2 2 1 1 AAA domain RNA_helicase PF00910.17 KLO04593.1 - 0.003 17.7 0.0 0.0086 16.2 0.0 1.8 1 0 0 1 1 1 1 RNA helicase AAA_10 PF12846.2 KLO04593.1 - 0.0034 16.8 0.4 0.0084 15.5 0.0 1.7 2 0 0 2 2 2 1 AAA-like domain MMR_HSR1 PF01926.18 KLO04593.1 - 0.0035 17.2 0.3 0.011 15.7 0.2 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase PduV-EutP PF10662.4 KLO04593.1 - 0.004 16.6 0.0 0.012 15.0 0.0 1.8 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation AAA PF00004.24 KLO04593.1 - 0.004 17.3 0.0 0.011 15.9 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) NACHT PF05729.7 KLO04593.1 - 0.0062 16.2 0.0 0.013 15.1 0.0 1.4 1 0 0 1 1 1 1 NACHT domain AAA_14 PF13173.1 KLO04593.1 - 0.0099 15.7 0.1 0.13 12.1 0.0 2.7 3 0 0 3 3 3 1 AAA domain Septin PF00735.13 KLO04593.1 - 0.021 13.8 0.0 0.048 12.6 0.0 1.5 1 0 0 1 1 1 0 Septin AAA_29 PF13555.1 KLO04593.1 - 0.022 14.2 0.1 0.072 12.6 0.0 1.8 2 0 0 2 2 1 0 P-loop containing region of AAA domain AAA_25 PF13481.1 KLO04593.1 - 0.038 13.3 0.0 0.096 12.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 KLO04593.1 - 0.054 13.8 0.2 0.054 13.8 0.1 3.8 5 1 0 5 5 2 0 AAA domain AAA_5 PF07728.9 KLO04593.1 - 0.059 13.0 0.1 0.12 12.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) DUF87 PF01935.12 KLO04593.1 - 0.065 13.0 0.1 0.065 13.0 0.1 2.4 3 0 0 3 3 2 0 Domain of unknown function DUF87 Cep57_MT_bd PF06657.8 KLO04594.1 - 1e-21 76.6 0.0 1e-21 76.6 0.0 3.7 4 0 0 4 4 4 1 Centrosome microtubule-binding domain of Cep57 Cep57_CLD_2 PF14197.1 KLO04594.1 - 7.1e-07 29.0 7.8 7.1e-07 29.0 5.4 2.7 2 1 0 2 2 2 1 Centrosome localisation domain of PPC89 Reo_sigmaC PF04582.7 KLO04594.1 - 0.024 13.8 3.5 0.029 13.5 0.6 2.1 2 0 0 2 2 2 0 Reovirus sigma C capsid protein IZUMO PF15005.1 KLO04594.1 - 0.047 13.7 1.3 0.11 12.5 0.8 1.7 1 1 0 1 1 1 0 Izumo sperm-egg fusion IncA PF04156.9 KLO04594.1 - 0.19 11.2 26.8 0.79 9.2 9.1 2.6 1 1 1 2 2 2 0 IncA protein DASH_Dad3 PF08656.5 KLO04594.1 - 8.2 6.2 9.1 1 9.0 1.3 2.8 2 0 0 2 2 2 0 DASH complex subunit Dad3 zf-BED PF02892.10 KLO04595.1 - 0.012 15.3 0.0 0.022 14.5 0.0 1.4 1 0 0 1 1 1 0 BED zinc finger Abhydrolase_8 PF06259.7 KLO04602.1 - 0.012 15.1 0.1 0.015 14.8 0.1 1.1 1 0 0 1 1 1 0 Alpha/beta hydrolase Tim17 PF02466.14 KLO04602.1 - 0.017 15.1 0.6 0.023 14.7 0.4 1.5 1 1 0 1 1 1 0 Tim17/Tim22/Tim23/Pmp24 family IFR3_antag PF14754.1 KLO04602.1 - 0.15 11.0 0.9 0.13 11.2 0.2 1.3 1 1 0 1 1 1 0 Papain-like auto-proteinase Lactonase PF10282.4 KLO04604.1 - 4.9e-44 150.8 0.0 6e-44 150.5 0.0 1.0 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller HTH_33 PF13592.1 KLO04606.1 - 0.049 13.1 0.0 0.098 12.2 0.0 1.5 1 0 0 1 1 1 0 Winged helix-turn helix BLOC1_2 PF10046.4 KLO04608.1 - 0.0011 19.1 0.7 0.004 17.2 0.1 2.1 1 1 1 2 2 2 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 IncA PF04156.9 KLO04608.1 - 0.19 11.2 7.5 0.47 10.0 5.2 1.6 1 1 0 1 1 1 0 IncA protein GAS PF13851.1 KLO04608.1 - 0.63 9.2 6.9 0.82 8.8 4.8 1.1 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding Med9 PF07544.8 KLO04608.1 - 2.8 7.7 10.5 2.6 7.8 0.8 3.2 2 1 0 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 WD40 PF00400.27 KLO04610.1 - 3.6e-14 51.9 9.4 3.1e-07 29.9 0.1 4.6 5 0 0 5 5 5 4 WD domain, G-beta repeat HTH_Tnp_Tc5 PF03221.11 KLO04611.1 - 1.6e-11 43.8 0.1 3.2e-11 42.8 0.1 1.5 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain MarR PF01047.17 KLO04611.1 - 0.0036 16.9 0.0 0.02 14.5 0.0 2.0 2 0 0 2 2 2 1 MarR family HTH_Tnp_4 PF13613.1 KLO04611.1 - 0.017 14.6 0.0 0.046 13.2 0.0 1.7 1 0 0 1 1 1 0 Helix-turn-helix of DDE superfamily endonuclease CENP-B_N PF04218.8 KLO04611.1 - 0.026 13.9 0.1 0.22 10.9 0.0 2.2 2 0 0 2 2 2 0 CENP-B N-terminal DNA-binding domain HTH_3 PF01381.17 KLO04611.1 - 0.037 13.8 0.0 0.1 12.4 0.0 1.7 2 0 0 2 2 2 0 Helix-turn-helix HTH_38 PF13936.1 KLO04611.1 - 0.042 13.3 0.1 0.083 12.4 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_28 PF13518.1 KLO04611.1 - 0.078 12.9 0.1 0.85 9.6 0.0 2.7 4 0 0 4 4 4 0 Helix-turn-helix domain HTH_23 PF13384.1 KLO04611.1 - 0.21 11.2 0.5 1.1 9.0 0.0 2.4 2 0 0 2 2 2 0 Homeodomain-like domain Tenui_NCP PF04876.7 KLO04612.1 - 0.051 13.1 0.0 0.068 12.7 0.0 1.1 1 0 0 1 1 1 0 Tenuivirus major non-capsid protein MaoC_dehydrat_N PF13452.1 KLO04613.1 - 0.048 13.4 0.1 0.082 12.7 0.0 1.4 1 0 0 1 1 1 0 N-terminal half of MaoC dehydratase tRNA_anti-codon PF01336.20 KLO04613.1 - 0.082 12.7 0.0 0.2 11.5 0.0 1.7 1 0 0 1 1 1 0 OB-fold nucleic acid binding domain F-box-like PF12937.2 KLO04614.1 - 3.8e-06 26.5 1.5 7.7e-06 25.5 0.0 2.4 3 0 0 3 3 3 1 F-box-like F-box PF00646.28 KLO04614.1 - 0.00032 20.2 0.7 0.0047 16.5 0.0 2.8 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.2 KLO04615.1 - 7e-05 22.4 3.6 0.00029 20.4 0.0 3.3 3 1 0 3 3 3 1 F-box-like TMF_TATA_bd PF12325.3 KLO04616.1 - 0.01 15.5 6.3 0.22 11.2 0.4 2.2 1 1 0 2 2 2 0 TATA element modulatory factor 1 TATA binding GAS PF13851.1 KLO04616.1 - 0.069 12.3 1.1 0.097 11.8 0.7 1.2 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding DUF724 PF05266.9 KLO04616.1 - 0.2 11.2 1.7 0.3 10.6 1.2 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF724) TMF_DNA_bd PF12329.3 KLO04616.1 - 0.23 11.2 2.5 0.25 11.1 0.3 1.9 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding Pox_A_type_inc PF04508.7 KLO04616.1 - 1.1 9.1 4.3 3.8 7.5 0.3 3.2 3 1 0 3 3 3 0 Viral A-type inclusion protein repeat BTB PF00651.26 KLO04617.1 - 0.00068 19.6 0.0 0.0011 18.8 0.0 1.5 1 1 0 1 1 1 1 BTB/POZ domain Erf4 PF10256.4 KLO04618.1 - 0.024 14.4 0.0 0.038 13.8 0.0 1.3 1 0 0 1 1 1 0 Golgin subfamily A member 7/ERF4 family BTB PF00651.26 KLO04619.1 - 0.0033 17.3 0.0 0.0091 15.9 0.0 1.7 2 0 0 2 2 2 1 BTB/POZ domain SinI PF08671.5 KLO04619.1 - 0.069 12.5 0.1 0.15 11.5 0.0 1.5 1 0 0 1 1 1 0 Anti-repressor SinI BTB PF00651.26 KLO04620.1 - 0.00079 19.3 0.0 0.0039 17.1 0.0 2.1 1 1 1 2 2 2 1 BTB/POZ domain Ribosomal_L37e PF01907.14 KLO04624.1 - 0.025 14.3 1.3 0.046 13.5 0.9 1.5 1 0 0 1 1 1 0 Ribosomal protein L37e Dehyd-heme_bind PF09098.5 KLO04624.1 - 0.13 11.7 0.0 0.16 11.3 0.0 1.1 1 0 0 1 1 1 0 Quinohemoprotein amine dehydrogenase A, alpha subunit, haem binding zf-nanos PF05741.8 KLO04624.1 - 0.14 12.1 1.6 0.29 11.1 0.5 1.9 2 0 0 2 2 2 0 Nanos RNA binding domain GRP PF07172.6 KLO04628.1 - 6 7.4 34.1 11 6.5 23.6 1.3 1 0 0 1 1 1 0 Glycine rich protein family Spt5-NGN PF03439.8 KLO04631.1 - 9.8e-11 41.2 0.0 5e-10 39.0 0.0 2.1 2 0 0 2 2 2 1 Early transcription elongation factor of RNA pol II, NGN section KOW PF00467.24 KLO04631.1 - 1.2e-05 24.8 18.8 0.004 16.8 0.8 3.7 3 0 0 3 3 3 3 KOW motif Spt5_N PF11942.3 KLO04631.1 - 0.0029 18.1 9.9 0.0055 17.2 6.8 1.4 1 0 0 1 1 1 1 Spt5 transcription elongation factor, acidic N-terminal DUF3160 PF11369.3 KLO04631.1 - 0.1 10.9 0.5 0.82 7.9 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3160) Phytochelatin_C PF09328.5 KLO04631.1 - 0.44 10.0 1.6 0.79 9.1 1.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1984) ATP-synt_E PF05680.7 KLO04632.1 - 0.035 14.0 0.2 0.035 14.0 0.2 2.0 2 0 0 2 2 2 0 ATP synthase E chain HTH_29 PF13551.1 KLO04633.1 - 0.00016 21.7 0.1 0.00017 21.6 0.0 1.0 1 0 0 1 1 1 1 Winged helix-turn helix HTH_32 PF13565.1 KLO04633.1 - 0.00021 22.0 0.0 0.00023 21.9 0.0 1.0 1 0 0 1 1 1 1 Homeodomain-like domain DDE_3 PF13358.1 KLO04634.1 - 1e-11 44.7 0.0 1.2e-11 44.5 0.0 1.0 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_3 PF13358.1 KLO04635.1 - 1.2e-09 38.0 0.0 1.7e-09 37.5 0.0 1.3 1 1 0 1 1 1 1 DDE superfamily endonuclease AAA_21 PF13304.1 KLO04637.1 - 1.6 8.5 5.3 0.22 11.4 0.4 1.9 2 1 0 2 2 2 0 AAA domain Reo_sigmaC PF04582.7 KLO04641.1 - 0.0014 17.8 0.8 0.0021 17.3 0.6 1.2 1 0 0 1 1 1 1 Reovirus sigma C capsid protein AAA_13 PF13166.1 KLO04641.1 - 0.0079 14.7 0.2 0.01 14.3 0.1 1.1 1 0 0 1 1 1 1 AAA domain Bacillus_HBL PF05791.6 KLO04641.1 - 0.0091 15.3 1.2 0.46 9.8 0.1 2.1 1 1 1 2 2 2 1 Bacillus haemolytic enterotoxin (HBL) HsbA PF12296.3 KLO04641.1 - 0.011 15.6 2.1 0.029 14.2 0.1 2.2 2 0 0 2 2 2 0 Hydrophobic surface binding protein A DUF812 PF05667.6 KLO04641.1 - 0.024 13.1 0.0 0.031 12.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF812) Img2 PF05046.9 KLO04641.1 - 0.026 14.7 1.5 0.11 12.6 0.2 2.5 1 1 1 2 2 2 0 Mitochondrial large subunit ribosomal protein (Img2) DUF1664 PF07889.7 KLO04641.1 - 0.028 14.1 0.5 0.058 13.1 0.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) SF-assemblin PF06705.6 KLO04641.1 - 0.029 13.5 2.0 0.15 11.2 0.1 2.0 1 1 1 2 2 2 0 SF-assemblin/beta giardin Baculo_PEP_C PF04513.7 KLO04641.1 - 0.031 14.1 7.7 0.086 12.6 5.2 1.9 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Laminin_II PF06009.7 KLO04641.1 - 0.04 13.6 0.4 0.11 12.3 0.1 1.8 1 1 0 1 1 1 0 Laminin Domain II Syntaxin PF00804.20 KLO04641.1 - 0.04 14.0 0.6 0.17 12.0 0.1 2.1 1 1 0 2 2 2 0 Syntaxin Apolipoprotein PF01442.13 KLO04641.1 - 0.056 12.9 0.0 0.099 12.1 0.0 1.4 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain NPV_P10 PF05531.7 KLO04641.1 - 0.06 13.5 2.6 1.2 9.4 1.8 2.3 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein EzrA PF06160.7 KLO04641.1 - 0.061 11.4 0.2 0.078 11.1 0.1 1.2 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA LPP PF04728.8 KLO04641.1 - 0.067 12.9 3.7 0.19 11.5 0.1 2.9 2 1 1 3 3 3 0 Lipoprotein leucine-zipper MscS_porin PF12795.2 KLO04641.1 - 0.1 11.9 0.2 0.2 10.9 0.2 1.4 1 1 0 1 1 1 0 Mechanosensitive ion channel porin domain DASH_Duo1 PF08651.5 KLO04641.1 - 0.1 12.1 0.2 0.39 10.3 0.1 2.0 1 1 1 2 2 2 0 DASH complex subunit Duo1 TBPIP PF07106.8 KLO04641.1 - 0.11 12.0 0.1 0.35 10.3 0.1 1.8 1 1 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Myosin_tail_1 PF01576.14 KLO04641.1 - 0.19 9.4 0.4 0.25 9.0 0.3 1.0 1 0 0 1 1 1 0 Myosin tail Mito_fiss_reg PF05308.6 KLO04641.1 - 0.23 10.7 5.7 0.46 9.8 3.9 1.4 1 0 0 1 1 1 0 Mitochondrial fission regulator Semialdhyde_dhC PF02774.13 KLO04644.1 - 0.074 12.9 0.0 0.14 12.0 0.0 1.5 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, dimerisation domain RRM_1 PF00076.17 KLO04644.1 - 0.088 12.4 0.0 0.22 11.1 0.0 1.6 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Siah-Interact_N PF09032.6 KLO04644.1 - 1.6 8.8 5.6 0.37 10.8 0.1 2.4 2 0 0 2 2 2 0 Siah interacting protein, N terminal NOA36 PF06524.7 KLO04644.1 - 3.1 6.9 14.5 7.1 5.7 10.1 1.6 1 0 0 1 1 1 0 NOA36 protein Nup_retrotrp_bd PF10599.4 KLO04646.1 - 0.28 11.8 3.2 0.77 10.4 0.6 2.2 2 0 0 2 2 2 0 Retro-transposon transporting motif NPV_P10 PF05531.7 KLO04653.1 - 0.0042 17.2 2.1 0.0095 16.1 1.5 1.6 1 0 0 1 1 1 1 Nucleopolyhedrovirus P10 protein Baculo_PEP_C PF04513.7 KLO04653.1 - 0.0076 16.0 4.1 0.021 14.6 2.8 1.7 1 1 0 1 1 1 1 Baculovirus polyhedron envelope protein, PEP, C terminus Apolipoprotein PF01442.13 KLO04653.1 - 0.022 14.2 0.3 0.022 14.2 0.2 1.8 2 1 0 2 2 2 0 Apolipoprotein A1/A4/E domain Phage_GP20 PF06810.6 KLO04653.1 - 0.024 14.0 12.4 0.017 14.5 4.8 2.3 2 0 0 2 2 2 0 Phage minor structural protein GP20 DUF1664 PF07889.7 KLO04653.1 - 0.044 13.5 0.5 0.086 12.6 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) DUF1933 PF09147.5 KLO04653.1 - 0.047 13.1 0.0 0.11 11.9 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1933) Retrotrans_gag PF03732.12 KLO04654.1 - 0.0018 18.2 0.0 0.0042 17.1 0.0 1.6 1 0 0 1 1 1 1 Retrotransposon gag protein Lipoprotein_3 PF00938.12 KLO04654.1 - 0.11 12.3 0.1 0.3 10.8 0.0 1.8 2 0 0 2 2 2 0 Lipoprotein DUF2797 PF10977.3 KLO04656.1 - 0.29 10.7 1.7 0.44 10.1 1.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2797) zf-B_box PF00643.19 KLO04656.1 - 2.8 7.8 11.0 0.17 11.8 3.6 2.1 2 1 0 2 2 2 0 B-box zinc finger ATP-synt_E PF05680.7 KLO04657.1 - 0.02 14.8 0.2 0.033 14.1 0.1 1.3 1 0 0 1 1 1 0 ATP synthase E chain Spt5-NGN PF03439.8 KLO04659.1 - 1.6e-07 30.9 0.0 3.7e-07 29.8 0.0 1.6 1 0 0 1 1 1 1 Early transcription elongation factor of RNA pol II, NGN section KOW PF00467.24 KLO04659.1 - 0.34 10.7 26.2 0.7 9.7 1.4 4.3 4 0 0 4 4 4 0 KOW motif Atg14 PF10186.4 KLO04661.1 - 0.041 12.8 0.2 0.067 12.1 0.1 1.3 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 HTH_1 PF00126.22 KLO04661.1 - 0.19 11.5 0.7 0.55 10.0 0.5 1.8 1 0 0 1 1 1 0 Bacterial regulatory helix-turn-helix protein, lysR family Polysacc_deac_1 PF01522.16 KLO04667.1 - 8.7e-09 35.0 0.0 1.8e-08 34.0 0.0 1.5 2 0 0 2 2 2 1 Polysaccharide deacetylase HTH_23 PF13384.1 KLO04667.1 - 0.047 13.3 0.1 0.13 11.9 0.0 1.8 2 0 0 2 2 2 0 Homeodomain-like domain F-box PF00646.28 KLO04669.1 - 0.00035 20.1 2.4 0.0019 17.7 0.1 2.7 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.2 KLO04669.1 - 0.00041 20.0 0.8 0.0051 16.5 0.0 2.7 2 0 0 2 2 2 1 F-box-like Corona_5a PF06336.6 KLO04669.1 - 0.064 13.1 0.0 0.14 12.0 0.0 1.4 1 0 0 1 1 1 0 Coronavirus 5a protein Hist_deacetyl PF00850.14 KLO04670.1 - 7.6e-63 212.6 0.1 1e-62 212.2 0.0 1.1 1 0 0 1 1 1 1 Histone deacetylase domain NatB_MDM20 PF09797.4 KLO04672.1 - 1e-68 231.7 0.1 1.7e-68 230.9 0.0 1.2 1 0 0 1 1 1 1 N-acetyltransferase B complex (NatB) non catalytic subunit TPR_14 PF13428.1 KLO04672.1 - 0.0021 18.5 2.0 0.42 11.3 0.0 4.6 5 1 0 5 5 5 1 Tetratricopeptide repeat BTAD PF03704.12 KLO04672.1 - 0.0029 17.9 0.0 0.012 15.9 0.0 2.2 1 0 0 1 1 1 1 Bacterial transcriptional activator domain BTB PF00651.26 KLO04673.1 - 1.9e-05 24.5 0.0 5.7e-05 23.0 0.0 1.9 2 1 0 2 2 2 1 BTB/POZ domain Zn_Tnp_IS1595 PF12760.2 KLO04673.1 - 0.069 12.9 0.2 0.16 11.8 0.2 1.6 1 1 0 1 1 1 0 Transposase zinc-ribbon domain RPA_C PF08784.6 KLO04674.1 - 0.0028 18.0 1.1 0.019 15.3 0.0 2.3 2 0 0 2 2 2 1 Replication protein A C terminal PINIT PF14324.1 KLO04674.1 - 0.18 11.8 1.4 0.51 10.4 0.9 1.8 1 1 0 1 1 1 0 PINIT domain DNase_NucA_NucB PF14040.1 KLO04675.1 - 0.013 15.6 0.0 0.1 12.7 0.0 1.9 1 1 1 2 2 2 0 Deoxyribonuclease NucA/NucB FG-GAP PF01839.18 KLO04679.1 - 0.011 15.3 0.1 0.057 13.1 0.1 2.3 1 0 0 1 1 1 0 FG-GAP repeat VCBS PF13517.1 KLO04679.1 - 0.012 15.9 6.6 0.38 11.1 0.2 3.8 3 0 0 3 3 3 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella F420_oxidored PF03807.12 KLO04680.1 - 0.0001 22.6 0.1 0.00016 22.0 0.1 1.5 1 1 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent 3HCDH_N PF02737.13 KLO04680.1 - 0.0017 18.0 0.0 0.002 17.8 0.0 1.1 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_Gly3P_dh_N PF01210.18 KLO04680.1 - 0.011 15.4 0.0 0.014 15.1 0.0 1.1 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus DAO PF01266.19 KLO04680.1 - 0.013 14.3 0.0 0.014 14.3 0.0 1.1 1 0 0 1 1 1 0 FAD dependent oxidoreductase NAD_binding_2 PF03446.10 KLO04680.1 - 0.043 13.6 0.0 0.11 12.3 0.0 1.6 1 1 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase TrkA_N PF02254.13 KLO04680.1 - 0.045 13.7 0.0 0.059 13.3 0.0 1.2 1 0 0 1 1 1 0 TrkA-N domain NAD_binding_8 PF13450.1 KLO04680.1 - 0.058 13.4 0.0 0.13 12.2 0.0 1.7 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain NAD_binding_7 PF13241.1 KLO04680.1 - 0.058 13.6 0.0 0.074 13.3 0.0 1.2 1 0 0 1 1 1 0 Putative NAD(P)-binding FAD_binding_3 PF01494.14 KLO04680.1 - 0.11 11.5 0.0 0.14 11.1 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain Epimerase PF01370.16 KLO04680.1 - 0.13 11.6 0.0 0.16 11.4 0.0 1.1 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family ADH_zinc_N PF00107.21 KLO04681.1 - 9.3e-17 60.7 0.0 1.6e-16 60.0 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KLO04681.1 - 1.2e-09 37.8 0.1 4.2e-09 36.1 0.0 1.8 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 KLO04681.1 - 6.2e-08 33.6 0.0 1.1e-07 32.7 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase THF_DHG_CYH_C PF02882.14 KLO04681.1 - 0.048 12.7 0.0 0.089 11.8 0.0 1.4 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain F-box-like PF12937.2 KLO04683.1 - 1.4e-11 43.9 3.5 1.8e-11 43.5 0.4 2.7 3 0 0 3 3 3 1 F-box-like F-box-like_2 PF13013.1 KLO04683.1 - 0.0083 15.8 0.2 0.019 14.6 0.1 1.7 1 0 0 1 1 1 1 F-box-like domain F-box PF00646.28 KLO04683.1 - 0.012 15.2 1.0 0.058 13.0 0.7 2.2 1 1 0 1 1 1 0 F-box domain Tet_JBP PF12851.2 KLO04685.1 - 2.4e-11 43.2 0.0 5.3e-11 42.1 0.0 1.6 1 0 0 1 1 1 1 Oxygenase domain of the 2OGFeDO superfamily Peptidase_C48 PF02902.14 KLO04687.1 - 8.5e-14 51.6 1.7 1.3e-13 51.0 1.2 1.3 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain ADIP PF11559.3 KLO04688.1 - 0.072 12.9 0.5 0.14 12.0 0.3 1.5 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding CENP-Q PF13094.1 KLO04688.1 - 0.13 12.2 3.8 0.28 11.1 0.1 2.6 3 1 0 3 3 3 0 CENP-Q, a CENPA-CAD centromere complex subunit Ribosomal_60s PF00428.14 KLO04688.1 - 0.25 11.7 2.2 0.5 10.7 1.5 1.5 1 0 0 1 1 1 0 60s Acidic ribosomal protein AT_hook PF02178.14 KLO04689.1 - 5.5 6.9 13.0 0.097 12.4 3.0 2.8 2 0 0 2 2 2 0 AT hook motif DDE_3 PF13358.1 KLO04690.1 - 2.7e-09 36.9 0.1 3.5e-09 36.5 0.1 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_3 PF13358.1 KLO04691.1 - 2e-09 37.3 0.0 2.1e-09 37.2 0.0 1.0 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_29 PF13551.1 KLO04692.1 - 2.6e-11 43.6 0.0 3.1e-11 43.3 0.0 1.1 1 0 0 1 1 1 1 Winged helix-turn helix HTH_32 PF13565.1 KLO04692.1 - 1.6e-08 35.1 0.4 2.2e-08 34.7 0.3 1.2 1 0 0 1 1 1 1 Homeodomain-like domain HTH_33 PF13592.1 KLO04692.1 - 1.5e-05 24.4 0.0 3.3e-05 23.3 0.0 1.5 1 0 0 1 1 1 1 Winged helix-turn helix HTH_Tnp_Tc3_2 PF01498.13 KLO04692.1 - 8.7e-05 22.5 0.2 0.00031 20.7 0.0 1.8 2 0 0 2 2 2 1 Transposase HTH_23 PF13384.1 KLO04692.1 - 0.00061 19.3 1.7 0.01 15.4 0.0 2.3 2 0 0 2 2 2 1 Homeodomain-like domain HTH_7 PF02796.10 KLO04692.1 - 0.035 13.9 0.7 0.92 9.4 0.0 2.8 3 0 0 3 3 3 0 Helix-turn-helix domain of resolvase HTH_28 PF13518.1 KLO04692.1 - 0.059 13.3 1.2 0.1 12.5 0.0 1.9 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_36 PF13730.1 KLO04692.1 - 0.075 13.1 0.0 0.42 10.7 0.0 2.0 2 0 0 2 2 2 0 Helix-turn-helix domain TrmB PF01978.14 KLO04692.1 - 0.087 12.5 0.0 0.17 11.5 0.0 1.5 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB zf-CCHC PF00098.18 KLO04694.1 - 0.043 13.7 0.2 0.062 13.2 0.2 1.3 1 0 0 1 1 1 0 Zinc knuckle Mucin PF01456.12 KLO04694.1 - 0.16 11.7 3.2 0.2 11.4 2.2 1.1 1 0 0 1 1 1 0 Mucin-like glycoprotein Pkinase_Tyr PF07714.12 KLO04698.1 - 2.7e-33 115.1 0.0 3.8e-33 114.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 KLO04698.1 - 3.8e-31 108.1 0.0 5.3e-31 107.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.1 KLO04698.1 - 0.1 11.5 0.0 0.15 10.9 0.0 1.2 1 0 0 1 1 1 0 Kinase-like Pkinase_Tyr PF07714.12 KLO04699.1 - 7.6e-32 110.4 0.0 8.9e-32 110.1 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 KLO04699.1 - 1.5e-31 109.5 0.0 1.8e-31 109.2 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.1 KLO04699.1 - 1.7e-06 27.2 0.0 2.1e-06 26.9 0.0 1.1 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 KLO04699.1 - 0.0033 16.5 0.0 0.0039 16.2 0.0 1.1 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 KLO04699.1 - 0.0092 15.3 0.0 0.012 14.9 0.0 1.2 1 0 0 1 1 1 1 RIO1 family APH PF01636.18 KLO04699.1 - 0.11 12.2 0.0 0.13 11.9 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family DUF1612 PF07756.7 KLO04701.1 - 0.26 11.4 2.4 0.39 10.8 1.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1612) Pkinase PF00069.20 KLO04704.1 - 4.3e-34 117.8 0.0 5.1e-34 117.5 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KLO04704.1 - 1.1e-28 100.0 0.0 1.8e-28 99.3 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KLO04704.1 - 0.0032 16.4 0.0 0.0049 15.8 0.0 1.2 1 0 0 1 1 1 1 Kinase-like DUF4398 PF14346.1 KLO04705.1 - 0.98 9.5 5.2 0.92 9.6 1.9 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4398) F-box-like PF12937.2 KLO04710.1 - 3.4e-05 23.4 2.0 0.075 12.7 0.0 2.9 2 1 0 2 2 2 2 F-box-like F-box PF00646.28 KLO04710.1 - 0.0045 16.5 7.8 0.31 10.7 0.4 4.0 4 1 0 4 4 4 2 F-box domain F-box-like PF12937.2 KLO04711.1 - 0.0032 17.1 0.2 0.0049 16.5 0.1 1.3 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KLO04711.1 - 0.023 14.3 0.4 0.11 12.2 0.3 1.9 1 1 0 1 1 1 0 F-box domain Cyclin PF08613.6 KLO04713.1 - 2.4e-09 37.7 0.0 2.8e-06 27.8 0.0 2.5 2 0 0 2 2 2 2 Cyclin Cyclin_N PF00134.18 KLO04713.1 - 0.042 13.4 0.0 0.072 12.6 0.0 1.3 1 0 0 1 1 1 0 Cyclin, N-terminal domain Transposase_21 PF02992.9 KLO04714.1 - 3.5e-12 45.8 0.0 1e-10 41.1 0.0 2.3 2 0 0 2 2 2 1 Transposase family tnp2 DUF4218 PF13960.1 KLO04714.1 - 0.034 13.6 0.1 0.073 12.5 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4218) TBPIP PF07106.8 KLO04715.1 - 0.055 13.0 7.0 0.2 11.1 4.8 2.0 1 0 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) FBP PF07299.6 KLO04715.1 - 0.19 11.0 1.6 0.41 9.9 1.1 1.6 1 0 0 1 1 1 0 Fibronectin-binding protein (FBP) AAA_13 PF13166.1 KLO04715.1 - 0.24 9.8 15.2 0.8 8.0 10.7 1.7 1 1 0 1 1 1 0 AAA domain Reo_sigmaC PF04582.7 KLO04715.1 - 2.2 7.3 9.5 2.8 7.0 2.0 2.4 1 1 2 3 3 3 0 Reovirus sigma C capsid protein SlyX PF04102.7 KLO04715.1 - 2.3 8.6 5.8 1.9 8.9 0.1 3.2 2 1 1 3 3 3 0 SlyX Fib_alpha PF08702.5 KLO04715.1 - 2.6 8.1 6.9 4 7.5 2.1 2.7 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family B_lectin PF01453.19 KLO04717.1 - 4.9e-09 36.0 0.0 5.9e-09 35.8 0.0 1.2 1 0 0 1 1 1 1 D-mannose binding lectin F-box-like PF12937.2 KLO04718.1 - 0.00079 19.1 0.7 0.0021 17.7 0.5 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KLO04718.1 - 0.13 12.0 2.1 0.62 9.7 1.5 2.3 1 0 0 1 1 1 0 F-box domain FUSC PF04632.7 KLO04722.1 - 0.16 10.3 8.2 0.2 10.0 5.7 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family GPI-anchored PF10342.4 KLO04724.1 - 0.00068 20.0 0.3 0.00086 19.7 0.2 1.2 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family uDENN PF03456.13 KLO04724.1 - 0.01 15.7 0.0 0.014 15.3 0.0 1.2 1 0 0 1 1 1 0 uDENN domain ATG11 PF10377.4 KLO04725.1 - 0.003 17.4 0.0 0.0044 16.9 0.0 1.2 1 0 0 1 1 1 1 Autophagy-related protein 11 CDC48_2 PF02933.12 KLO04725.1 - 0.094 12.3 0.0 0.17 11.5 0.0 1.4 1 0 0 1 1 1 0 Cell division protein 48 (CDC48), domain 2 rve PF00665.21 KLO04726.1 - 0.042 13.9 0.0 0.08 13.0 0.0 1.5 2 0 0 2 2 2 0 Integrase core domain DUF4293 PF14126.1 KLO04729.1 - 0.11 12.3 0.1 0.2 11.5 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4293) Glycogen_syn PF05693.8 KLO04732.1 - 0 1091.5 0.0 0 1091.2 0.0 1.0 1 0 0 1 1 1 1 Glycogen synthase Glycos_transf_1 PF00534.15 KLO04732.1 - 3.8e-08 32.9 0.0 2e-05 24.1 0.0 2.3 2 0 0 2 2 2 2 Glycosyl transferases group 1 Glyco_transf_5 PF08323.6 KLO04732.1 - 1e-07 31.7 0.1 3.3e-07 30.0 0.0 1.9 2 0 0 2 2 2 1 Starch synthase catalytic domain Glyco_trans_4_4 PF13579.1 KLO04732.1 - 4.9e-06 26.7 0.0 1.1e-05 25.6 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain zf-C2HC_2 PF13913.1 KLO04736.1 - 6.6 6.5 6.7 1 9.1 1.8 1.8 2 0 0 2 2 2 0 zinc-finger of a C2HC-type Hexapep PF00132.19 KLO04740.1 - 1.1e-13 50.0 17.7 1.7e-07 30.3 0.5 4.3 3 1 1 4 4 4 3 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.1 KLO04740.1 - 6.7e-07 28.7 15.3 5e-05 22.7 2.0 3.7 3 1 1 4 4 4 3 Hexapeptide repeat of succinyl-transferase Fucokinase PF07959.7 KLO04740.1 - 0.00039 19.1 0.0 0.00051 18.7 0.0 1.2 1 0 0 1 1 1 1 L-fucokinase NP1-WLL PF11733.3 KLO04741.1 - 0.045 13.9 0.2 0.095 12.9 0.2 1.4 1 0 0 1 1 1 0 Non-capsid protein NP1 XPG_I PF00867.13 KLO04744.1 - 2.5e-16 59.5 0.0 4.8e-16 58.6 0.0 1.5 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.12 KLO04744.1 - 0.0014 18.8 0.0 0.0021 18.2 0.0 1.2 1 0 0 1 1 1 1 XPG N-terminal domain Phage_int_SAM_4 PF13495.1 KLO04745.1 - 0.017 15.4 0.8 0.11 12.7 0.0 2.7 3 0 0 3 3 3 0 Phage integrase, N-terminal SAM-like domain Ribosomal_S8 PF00410.14 KLO04746.1 - 3.9e-20 71.9 0.0 6.1e-20 71.3 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S8 Retrotrans_gag PF03732.12 KLO04749.1 - 0.0039 17.2 3.1 0.0071 16.3 0.3 2.3 1 1 1 2 2 2 1 Retrotransposon gag protein MRP-S33 PF08293.6 KLO04749.1 - 0.13 12.2 0.4 1.4 8.9 0.1 2.3 1 1 1 2 2 2 0 Mitochondrial ribosomal subunit S27 DUF3759 PF12585.3 KLO04752.1 - 0.00046 20.0 0.2 0.00081 19.2 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3759) HIT PF01230.18 KLO04754.1 - 7e-23 81.0 0.4 9.3e-23 80.6 0.3 1.2 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.3 KLO04754.1 - 1.5e-12 47.7 0.3 1.9e-12 47.4 0.2 1.1 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding CwfJ_C_1 PF04677.10 KLO04754.1 - 2.4e-05 23.9 0.0 3.6e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 NOT2_3_5 PF04153.13 KLO04755.1 - 2.2e-31 108.5 1.3 2.2e-31 108.5 0.9 2.0 2 0 0 2 2 2 1 NOT2 / NOT3 / NOT5 family ENTH PF01417.15 KLO04756.1 - 1.2e-42 144.6 0.2 1.8e-42 144.1 0.1 1.3 1 0 0 1 1 1 1 ENTH domain ANTH PF07651.11 KLO04756.1 - 0.0032 16.2 0.1 0.0052 15.5 0.0 1.3 1 0 0 1 1 1 1 ANTH domain GRP PF07172.6 KLO04756.1 - 0.022 15.2 15.3 0.022 15.2 10.6 2.4 3 0 0 3 3 3 0 Glycine rich protein family PAT1 PF09770.4 KLO04756.1 - 0.93 7.6 11.1 0.29 9.3 5.4 1.8 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 F1F0-ATPsyn_F PF10791.4 KLO04757.1 - 2.3e-25 88.6 0.1 2.6e-25 88.4 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial F1-F0 ATP synthase subunit F of fungi SQS_PSY PF00494.14 KLO04758.1 - 2.9e-17 62.8 0.0 3.4e-17 62.6 0.0 1.1 1 0 0 1 1 1 1 Squalene/phytoene synthase Tis11B_N PF04553.7 KLO04759.1 - 0.068 13.3 0.0 0.097 12.8 0.0 1.2 1 0 0 1 1 1 0 Tis11B like protein, N terminus DUF2457 PF10446.4 KLO04763.1 - 0.051 12.2 0.1 0.055 12.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Complex1_LYR PF05347.10 KLO04765.1 - 2.1e-10 40.2 3.2 2.6e-10 39.9 2.2 1.1 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 KLO04765.1 - 1.8e-09 37.6 2.6 2.2e-09 37.3 1.8 1.1 1 0 0 1 1 1 1 Complex1_LYR-like LuxS PF02664.10 KLO04765.1 - 0.076 12.5 0.0 0.089 12.3 0.0 1.1 1 0 0 1 1 1 0 S-Ribosylhomocysteinase (LuxS) zf-MYND PF01753.13 KLO04772.1 - 1.9e-06 27.6 8.1 4.9e-06 26.3 5.6 1.7 1 0 0 1 1 1 1 MYND finger Use1 PF09753.4 KLO04772.1 - 0.11 11.9 0.0 0.17 11.2 0.0 1.2 1 0 0 1 1 1 0 Membrane fusion protein Use1 LRR_8 PF13855.1 KLO04773.1 - 0.012 15.3 0.7 3.5 7.4 0.0 2.8 2 0 0 2 2 2 0 Leucine rich repeat Glyoxalase PF00903.20 KLO04773.1 - 0.013 15.5 0.0 0.023 14.7 0.0 1.5 1 0 0 1 1 1 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily zf-MYND PF01753.13 KLO04774.1 - 0.012 15.5 14.3 0.021 14.7 9.9 1.4 1 0 0 1 1 1 0 MYND finger CENP-B_dimeris PF09026.5 KLO04775.1 - 0.00068 19.8 8.3 0.00068 19.8 5.7 2.6 2 0 0 2 2 2 1 Centromere protein B dimerisation domain TRAP_alpha PF03896.11 KLO04775.1 - 1.1 8.2 5.8 2.7 6.9 4.0 1.6 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Spt5-NGN PF03439.8 KLO04776.1 - 5.4e-12 45.2 0.0 1.2e-11 44.2 0.0 1.6 1 0 0 1 1 1 1 Early transcription elongation factor of RNA pol II, NGN section Stathmin PF00836.14 KLO04776.1 - 0.036 13.6 6.4 0.075 12.6 4.5 1.4 1 0 0 1 1 1 0 Stathmin family KOW PF00467.24 KLO04776.1 - 0.072 12.8 0.3 0.072 12.8 0.2 3.5 3 0 0 3 3 3 0 KOW motif Ycf1 PF05758.7 KLO04776.1 - 2.2 5.9 3.2 3.1 5.4 2.2 1.1 1 0 0 1 1 1 0 Ycf1 Nop14 PF04147.7 KLO04777.1 - 4 5.2 12.9 5.8 4.7 8.9 1.1 1 0 0 1 1 1 0 Nop14-like family zf-CCHC_3 PF13917.1 KLO04779.1 - 0.033 13.9 0.4 0.058 13.1 0.3 1.4 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_5 PF14787.1 KLO04779.1 - 0.038 13.4 3.7 0.064 12.7 2.6 1.4 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger UBN2_2 PF14227.1 KLO04779.1 - 0.12 11.9 0.1 0.18 11.3 0.0 1.3 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type Phage_int_SAM_3 PF14659.1 KLO04780.1 - 0.0029 17.8 0.0 0.007 16.6 0.0 1.6 1 0 0 1 1 1 1 Phage integrase, N-terminal SAM-like domain KOW PF00467.24 KLO04790.1 - 2.4e-10 39.7 28.1 0.0025 17.4 0.2 7.1 7 0 0 7 7 7 4 KOW motif Spt5-NGN PF03439.8 KLO04790.1 - 3.6e-10 39.4 0.0 1.1e-09 37.8 0.0 1.9 1 0 0 1 1 1 1 Early transcription elongation factor of RNA pol II, NGN section DUF3912 PF13051.1 KLO04790.1 - 0.11 12.2 0.0 0.31 10.8 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3912) DUF4438 PF14505.1 KLO04790.1 - 0.12 11.1 6.9 7.4 5.2 0.0 4.4 4 1 0 5 5 5 0 Domain of unknown function (DUF4438) Spt5_N PF11942.3 KLO04790.1 - 4.7 7.8 18.2 0.32 11.6 8.9 1.8 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal Clathrin_lg_ch PF01086.12 KLO04792.1 - 0.06 13.2 1.2 0.069 13.0 0.9 1.2 1 0 0 1 1 1 0 Clathrin light chain TFIIA PF03153.8 KLO04796.1 - 0.00052 20.0 6.2 0.00094 19.1 4.3 1.3 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Sigma70_ner PF04546.8 KLO04796.1 - 0.067 12.7 7.4 0.17 11.4 5.1 1.7 1 0 0 1 1 1 0 Sigma-70, non-essential region Nop14 PF04147.7 KLO04796.1 - 0.18 9.6 16.4 0.27 9.1 11.4 1.1 1 0 0 1 1 1 0 Nop14-like family DNA_pol_phi PF04931.8 KLO04796.1 - 0.24 9.1 15.6 0.39 8.4 10.8 1.3 1 0 0 1 1 1 0 DNA polymerase phi Daxx PF03344.10 KLO04796.1 - 0.48 8.8 12.2 0.82 8.0 8.5 1.3 1 0 0 1 1 1 0 Daxx Family Glypican PF01153.14 KLO04796.1 - 1 7.8 4.5 1.5 7.3 3.1 1.2 1 0 0 1 1 1 0 Glypican CBM_19 PF03427.8 KLO04797.1 - 0.018 14.8 0.1 0.027 14.2 0.1 1.3 1 0 0 1 1 1 0 Carbohydrate binding domain (family 19) WD40 PF00400.27 KLO04798.1 - 1.5e-08 34.2 6.3 1.8e-05 24.4 0.7 3.2 3 0 0 3 3 3 2 WD domain, G-beta repeat Hrs_helical PF12210.3 KLO04799.1 - 0.0091 16.2 0.2 0.01 16.0 0.1 1.2 1 0 0 1 1 1 1 Hepatocyte growth factor-regulated tyrosine kinase substrate Asp_protease_2 PF13650.1 KLO04804.1 - 0.0024 18.3 0.0 0.0066 16.9 0.0 1.8 1 0 0 1 1 1 1 Aspartyl protease Endonuc-dimeris PF09124.5 KLO04805.1 - 0.16 11.5 0.2 14 5.4 0.0 2.3 1 1 1 2 2 2 0 T4 recombination endonuclease VII, dimerisation Bromodomain PF00439.20 KLO04806.1 - 0.092 12.6 0.0 0.15 12.0 0.0 1.4 1 0 0 1 1 1 0 Bromodomain F-box-like PF12937.2 KLO04808.1 - 0.11 12.2 0.0 0.11 12.2 0.0 2.4 3 0 0 3 3 3 0 F-box-like F-box-like PF12937.2 KLO04811.1 - 0.0012 18.5 0.0 0.0037 16.9 0.0 2.0 1 0 0 1 1 1 1 F-box-like F-box-like PF12937.2 KLO04812.1 - 0.037 13.7 0.1 0.097 12.4 0.1 1.7 1 0 0 1 1 1 0 F-box-like BAG PF02179.11 KLO04812.1 - 0.13 12.4 0.0 14 5.8 0.0 2.6 2 0 0 2 2 2 0 BAG domain F-box-like PF12937.2 KLO04813.1 - 0.00013 21.6 0.2 0.00046 19.8 0.1 2.0 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.2 KLO04813.1 - 0.034 13.7 1.3 0.32 10.6 0.0 3.0 3 0 0 3 3 3 0 Leucine Rich repeats (2 copies) F-box-like PF12937.2 KLO04815.1 - 1.7e-09 37.2 0.2 6.8e-08 32.1 0.0 3.0 3 0 0 3 3 3 1 F-box-like F-box-like PF12937.2 KLO04816.1 - 3.6e-09 36.2 0.2 1.2e-08 34.5 0.1 1.9 1 0 0 1 1 1 1 F-box-like Abhydrolase_6 PF12697.2 KLO04816.1 - 0.011 15.6 0.0 0.055 13.3 0.0 2.0 2 0 0 2 2 2 0 Alpha/beta hydrolase family F-box PF00646.28 KLO04816.1 - 0.042 13.5 0.0 0.16 11.6 0.0 2.0 1 0 0 1 1 1 0 F-box domain LRR_2 PF07723.8 KLO04816.1 - 0.052 14.0 0.2 0.21 12.1 0.1 2.1 1 0 0 1 1 1 0 Leucine Rich Repeat Abhydrolase_5 PF12695.2 KLO04816.1 - 0.11 12.2 0.0 0.17 11.6 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family Polysacc_lyase PF14099.1 KLO04817.1 - 0.002 17.8 0.1 0.0029 17.3 0.1 1.3 1 0 0 1 1 1 1 Polysaccharide lyase DUF2782 PF11191.3 KLO04820.1 - 0.044 13.7 0.0 0.054 13.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2782) SLT PF01464.15 KLO04822.1 - 4.3e-12 45.6 0.0 6.8e-12 44.9 0.0 1.3 1 0 0 1 1 1 1 Transglycosylase SLT domain ERO1 PF04137.10 KLO04823.1 - 6e-118 393.9 0.0 7.8e-118 393.5 0.0 1.1 1 0 0 1 1 1 1 Endoplasmic Reticulum Oxidoreductin 1 (ERO1) Phage_integrase PF00589.17 KLO04825.1 - 0.0013 18.4 0.0 0.0092 15.6 0.0 2.1 1 1 0 1 1 1 1 Phage integrase family XPG_I PF00867.13 KLO04826.1 - 8e-15 54.6 0.0 1.3e-14 53.9 0.0 1.3 1 0 0 1 1 1 1 XPG I-region Cauli_VI PF01693.11 KLO04828.1 - 0.0027 17.6 0.0 0.0051 16.8 0.0 1.4 1 0 0 1 1 1 1 Caulimovirus viroplasmin CLASP_N PF12348.3 KLO04831.1 - 1.4e-69 233.9 0.0 1.9e-59 200.8 0.0 4.0 3 1 0 3 3 3 2 CLASP N terminal HEAT PF02985.17 KLO04831.1 - 4.7e-07 29.3 0.0 0.77 10.0 0.0 5.8 5 0 0 5 5 5 2 HEAT repeat HEAT_2 PF13646.1 KLO04831.1 - 6.1e-06 26.4 1.1 1.5 9.1 0.0 5.5 5 1 0 5 5 5 2 HEAT repeats Cnd1 PF12717.2 KLO04831.1 - 0.00092 19.1 0.0 0.034 13.9 0.0 3.1 4 0 0 4 4 4 1 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.1 KLO04831.1 - 0.011 16.1 5.9 0.25 11.9 0.0 5.1 5 0 0 5 5 5 0 HEAT-like repeat Adaptin_N PF01602.15 KLO04831.1 - 0.061 11.6 0.1 2 6.6 0.0 3.0 4 0 0 4 4 4 0 Adaptin N terminal region Rhomboid PF01694.17 KLO04832.1 - 2.9e-24 85.7 8.4 2.9e-24 85.7 5.8 1.5 2 0 0 2 2 2 1 Rhomboid family EcsB PF05975.7 KLO04832.1 - 0.1 11.0 3.0 0.13 10.6 2.1 1.2 1 0 0 1 1 1 0 Bacterial ABC transporter protein EcsB PAT1 PF09770.4 KLO04833.1 - 5.6 5.0 18.3 8.2 4.5 12.7 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Sedlin_N PF04628.8 KLO04834.1 - 1.5e-35 121.9 0.0 1.1e-29 102.9 0.0 2.2 2 0 0 2 2 2 2 Sedlin, N-terminal conserved region Sybindin PF04099.7 KLO04834.1 - 8.4e-06 25.5 0.0 0.038 13.7 0.0 2.4 3 0 0 3 3 3 2 Sybindin-like family UBN2_2 PF14227.1 KLO04835.1 - 0.03 13.8 0.1 0.076 12.5 0.1 1.7 1 1 1 2 2 2 0 gag-polypeptide of LTR copia-type Asp_protease_2 PF13650.1 KLO04836.1 - 0.00011 22.6 0.1 0.00022 21.6 0.1 1.5 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.15 KLO04836.1 - 0.0013 18.6 1.4 0.0023 17.8 0.1 2.0 2 0 0 2 2 2 1 Retroviral aspartyl protease Herpes_ORF11 PF04797.8 KLO04836.1 - 0.0048 15.4 0.0 0.0079 14.6 0.0 1.2 1 0 0 1 1 1 1 Herpesvirus dUTPase protein Peptidase_A2B PF12384.3 KLO04836.1 - 0.076 12.3 0.0 0.11 11.8 0.0 1.2 1 0 0 1 1 1 0 Ty3 transposon peptidase Exc PF07825.6 KLO04844.1 - 0.11 12.2 0.1 0.26 11.0 0.0 1.7 2 0 0 2 2 2 0 Excisionase-like protein DUF4218 PF13960.1 KLO04848.1 - 6.4e-05 22.3 1.4 0.00016 21.1 0.1 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF4218) Transposase_21 PF02992.9 KLO04849.1 - 3.9e-08 32.6 0.0 3.9e-08 32.6 0.0 1.0 1 0 0 1 1 1 1 Transposase family tnp2 BTB PF00651.26 KLO04855.1 - 2.3e-07 30.7 0.1 1.5e-05 24.9 0.0 2.9 3 0 0 3 3 3 1 BTB/POZ domain BTB PF00651.26 KLO04856.1 - 2.2e-05 24.4 0.2 0.00012 22.0 0.1 2.3 1 1 0 1 1 1 1 BTB/POZ domain F-box-like PF12937.2 KLO04857.1 - 0.056 13.1 0.4 0.25 11.0 0.1 2.2 2 1 1 3 3 3 0 F-box-like WD40 PF00400.27 KLO04860.1 - 0.00069 19.4 1.3 2.6 8.0 0.0 3.9 4 0 0 4 4 4 3 WD domain, G-beta repeat Glyco_transf_11 PF01531.11 KLO04862.1 - 0.051 12.5 0.0 0.12 11.3 0.0 1.6 1 0 0 1 1 1 0 Glycosyl transferase family 11 Fcf1 PF04900.7 KLO04864.1 - 2.2e-28 98.2 0.0 3.3e-28 97.7 0.0 1.3 1 0 0 1 1 1 1 Fcf1 DUF2638 PF10937.3 KLO04865.1 - 2.4 9.2 8.4 0.58 11.1 2.2 2.4 2 2 0 2 2 2 0 Protein of unknown function (DUF2638) Phosphodiest PF01663.17 KLO04873.1 - 1.3e-11 44.5 0.3 2.2e-11 43.7 0.2 1.3 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Metalloenzyme PF01676.13 KLO04873.1 - 0.0002 20.8 0.5 0.00032 20.1 0.3 1.2 1 0 0 1 1 1 1 Metalloenzyme superfamily Sulfatase PF00884.18 KLO04873.1 - 0.0065 15.6 0.0 0.012 14.8 0.0 1.4 1 0 0 1 1 1 1 Sulfatase Cyclin_N PF00134.18 KLO04875.1 - 0.0063 16.0 0.2 0.19 11.2 0.1 2.9 1 1 0 1 1 1 1 Cyclin, N-terminal domain DUF4419 PF14388.1 KLO04876.1 - 2.9e-88 295.9 0.1 3.4e-86 289.1 0.0 2.0 2 0 0 2 2 2 2 Domain of unknown function (DUF4419) Muted PF14942.1 KLO04877.1 - 0.33 10.8 2.3 1.2 9.0 1.5 1.8 1 1 1 2 2 2 0 Organelle biogenesis, Muted-like protein Exo_endo_phos PF03372.18 KLO04878.1 - 6.8e-08 32.7 0.0 1.2e-07 31.9 0.0 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.1 KLO04878.1 - 0.0061 16.1 0.3 0.15 11.7 0.1 2.6 2 1 0 2 2 2 1 Endonuclease-reverse transcriptase MaoC_dehydrat_N PF13452.1 KLO04878.1 - 0.13 12.0 0.1 0.37 10.5 0.0 1.8 1 0 0 1 1 1 0 N-terminal half of MaoC dehydratase PEX11 PF05648.9 KLO04879.1 - 0.036 13.3 0.6 0.084 12.1 0.1 1.9 2 0 0 2 2 2 0 Peroxisomal biogenesis factor 11 (PEX11) NfeD PF01957.13 KLO04879.1 - 0.12 12.4 4.7 2.5 8.2 0.3 2.3 2 0 0 2 2 2 0 NfeD-like C-terminal, partner-binding DUF4231 PF14015.1 KLO04879.1 - 0.21 11.6 9.4 0.12 12.3 1.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF4231) Chromo PF00385.19 KLO04882.1 - 0.00013 21.5 0.0 0.00018 21.0 0.0 1.3 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain A2L_zn_ribbon PF08792.5 KLO04883.1 - 5.6 6.5 6.6 1 8.9 0.0 2.8 3 0 0 3 3 3 0 A2L zinc ribbon domain PIF1 PF05970.9 KLO04884.1 - 1e-15 57.5 0.6 1.2e-15 57.3 0.4 1.0 1 0 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.1 KLO04884.1 - 7.3e-12 45.2 0.1 1e-11 44.7 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 KLO04884.1 - 3.3e-05 23.5 0.2 7.1e-05 22.4 0.1 1.6 1 1 1 2 2 2 1 Part of AAA domain AAA_5 PF07728.9 KLO04884.1 - 0.002 17.8 0.0 0.0029 17.3 0.0 1.3 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) ATP_bind_1 PF03029.12 KLO04884.1 - 0.008 15.7 0.0 0.016 14.7 0.0 1.5 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein ArgK PF03308.11 KLO04884.1 - 0.012 14.4 0.0 0.014 14.1 0.0 1.2 1 0 0 1 1 1 0 ArgK protein AAA PF00004.24 KLO04884.1 - 0.014 15.5 0.1 0.027 14.6 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Viral_helicase1 PF01443.13 KLO04884.1 - 0.021 14.3 0.2 0.042 13.3 0.0 1.6 2 1 0 2 2 2 0 Viral (Superfamily 1) RNA helicase AAA_22 PF13401.1 KLO04884.1 - 0.022 14.8 0.1 0.057 13.5 0.0 1.7 1 1 1 2 2 2 0 AAA domain ResIII PF04851.10 KLO04884.1 - 0.032 14.0 0.2 0.067 13.0 0.1 1.5 1 1 1 2 2 2 0 Type III restriction enzyme, res subunit AAA_16 PF13191.1 KLO04884.1 - 0.068 13.1 0.0 0.076 12.9 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain Zeta_toxin PF06414.7 KLO04884.1 - 0.077 12.0 0.0 0.13 11.3 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_11 PF13086.1 KLO04884.1 - 0.12 11.9 0.2 0.82 9.1 0.0 2.0 1 1 1 2 2 2 0 AAA domain Helitron_like_N PF14214.1 KLO04888.1 - 7.6e-11 42.0 0.0 1.5e-10 41.1 0.0 1.5 1 1 0 1 1 1 1 Helitron helicase-like domain at N-terminus Sulfatase PF00884.18 KLO04888.1 - 0.0043 16.2 0.1 0.0049 16.1 0.0 1.0 1 0 0 1 1 1 1 Sulfatase Hypoth_Ymh PF09509.5 KLO04888.1 - 0.12 12.0 0.0 0.22 11.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (Hypoth_ymh) Chromo PF00385.19 KLO04893.1 - 4.6e-10 39.0 0.1 6e-10 38.6 0.0 1.1 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Asp_protease_2 PF13650.1 KLO04896.1 - 6e-05 23.4 0.0 0.00015 22.1 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.15 KLO04896.1 - 0.0019 18.0 0.1 0.004 17.0 0.1 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease Retrotrans_gag PF03732.12 KLO04897.1 - 0.0035 17.3 1.6 0.0061 16.6 0.4 2.0 2 1 0 2 2 2 1 Retrotransposon gag protein RAB3GAP2_N PF14655.1 KLO04897.1 - 0.099 11.6 0.0 0.11 11.4 0.0 1.1 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus Alpha_L_fucos PF01120.12 KLO04898.1 - 0.046 12.6 0.0 0.056 12.3 0.0 1.1 1 0 0 1 1 1 0 Alpha-L-fucosidase GSH_synth_ATP PF03917.12 KLO04901.1 - 9.6e-53 179.0 0.0 1.2e-52 178.7 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic glutathione synthase, ATP binding domain GSH_synthase PF03199.10 KLO04901.1 - 3.2e-33 113.9 0.0 4.9e-33 113.3 0.0 1.3 1 0 0 1 1 1 1 Eukaryotic glutathione synthase Fe-S_biosyn PF01521.15 KLO04902.1 - 1.6e-12 47.3 0.0 2.2e-12 46.9 0.0 1.2 1 0 0 1 1 1 1 Iron-sulphur cluster biosynthesis NDUF_B4 PF07225.7 KLO04904.1 - 0.13 12.1 0.0 0.13 12.0 0.0 1.1 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase B15 subunit (NDUFB4) Spt5-NGN PF03439.8 KLO04909.1 - 1.6e-07 30.9 1.9 4.5e-07 29.5 0.0 2.6 3 0 0 3 3 3 1 Early transcription elongation factor of RNA pol II, NGN section KOW PF00467.24 KLO04909.1 - 0.029 14.1 0.6 0.029 14.1 0.5 5.1 5 0 0 5 5 5 0 KOW motif Cut8_N PF14482.1 KLO04909.1 - 0.092 12.7 1.7 0.25 11.3 1.2 1.8 1 0 0 1 1 1 0 Cut8 proteasome-binding domain HMG_box_2 PF09011.5 KLO04910.1 - 4.6e-05 23.7 2.4 0.00019 21.7 1.3 2.3 1 1 1 2 2 2 1 HMG-box domain HMG_box PF00505.14 KLO04910.1 - 0.0032 17.7 2.3 0.032 14.4 0.3 3.2 3 0 0 3 3 3 1 HMG (high mobility group) box AT_hook PF02178.14 KLO04910.1 - 0.04 13.5 4.4 0.15 11.7 3.0 2.1 1 0 0 1 1 1 0 AT hook motif FUN14 PF04930.10 KLO04910.1 - 0.33 11.2 1.7 0.74 10.1 0.2 2.2 2 1 0 2 2 2 0 FUN14 family PseudoU_synth_1 PF01416.15 KLO04912.1 - 9.2e-20 71.0 0.0 2e-10 40.9 0.0 2.4 2 0 0 2 2 2 2 tRNA pseudouridine synthase Pkinase PF00069.20 KLO04913.1 - 1.4e-08 34.2 0.1 1.9e-07 30.5 0.0 2.2 2 0 0 2 2 2 1 Protein kinase domain Kdo PF06293.9 KLO04913.1 - 2.9e-05 23.2 0.2 0.016 14.2 0.1 2.3 2 0 0 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_Tyr PF07714.12 KLO04913.1 - 0.012 14.6 0.0 0.021 13.9 0.0 1.4 1 0 0 1 1 1 0 Protein tyrosine kinase LEA_6 PF10714.4 KLO04913.1 - 0.1 12.3 0.3 0.31 10.8 0.1 1.9 2 0 0 2 2 2 0 Late embryogenesis abundant protein 18 DUF805 PF05656.9 KLO04914.1 - 0.0006 19.6 0.2 0.00086 19.1 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF805) Abi PF02517.11 KLO04914.1 - 0.23 11.5 3.6 1.5 9.0 2.5 1.9 1 1 0 1 1 1 0 CAAX protease self-immunity Glyco_hydro_47 PF01532.15 KLO04917.1 - 3.8e-136 454.3 0.0 4.5e-136 454.1 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Herpes_TK PF00693.13 KLO04920.1 - 0.094 11.8 0.3 0.12 11.4 0.2 1.3 1 0 0 1 1 1 0 Thymidine kinase from herpesvirus zf-C4H2 PF10146.4 KLO04925.1 - 0.043 13.8 0.3 0.054 13.5 0.2 1.1 1 0 0 1 1 1 0 Zinc finger-containing protein GAS2 PF02187.12 KLO04927.1 - 0.11 12.3 0.0 0.14 11.9 0.0 1.2 1 0 0 1 1 1 0 Growth-Arrest-Specific Protein 2 Domain DUF3657 PF12394.3 KLO04927.1 - 0.13 12.4 0.1 0.36 10.9 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3657) Cellulose_synt PF03552.9 KLO04929.1 - 0.11 10.7 0.2 0.18 10.0 0.2 1.2 1 0 0 1 1 1 0 Cellulose synthase DUF3272 PF11676.3 KLO04929.1 - 1.8 8.6 8.6 16 5.6 3.7 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3272) Extensin_2 PF04554.8 KLO04931.1 - 6.1 6.7 8.7 49 3.8 2.8 2.8 2 1 0 2 2 2 0 Extensin-like region DUF3678 PF12435.3 KLO04932.1 - 0.28 10.7 3.1 0.61 9.7 2.1 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3678) DUF3886 PF13025.1 KLO04937.1 - 1.1 9.2 9.1 0.77 9.7 2.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3886) F-box-like PF12937.2 KLO04939.1 - 3.4e-10 39.4 3.6 1.6e-09 37.3 2.5 2.2 1 1 0 1 1 1 1 F-box-like F-box PF00646.28 KLO04939.1 - 0.92 9.2 7.5 0.18 11.5 1.9 2.3 2 0 0 2 2 2 0 F-box domain F-box-like PF12937.2 KLO04940.1 - 9.4e-12 44.4 8.1 8.3e-11 41.4 2.4 3.6 3 1 0 3 3 3 1 F-box-like F-box PF00646.28 KLO04940.1 - 2 8.1 7.4 60 3.4 5.1 2.9 1 1 0 1 1 1 0 F-box domain F-box-like PF12937.2 KLO04941.1 - 9.7e-11 41.2 5.9 1.9e-10 40.2 2.7 2.5 2 1 0 2 2 2 1 F-box-like F-box PF00646.28 KLO04941.1 - 0.012 15.2 5.7 1.1 9.0 0.5 3.1 3 0 0 3 3 3 0 F-box domain GMC_oxred_N PF00732.14 KLO04945.1 - 7.7e-65 218.9 0.0 9.8e-65 218.6 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 KLO04945.1 - 1.1e-34 119.8 0.0 1.8e-34 119.0 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 KLO04945.1 - 5.5e-05 22.2 0.5 0.00025 20.0 0.2 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KLO04945.1 - 0.00019 21.3 0.0 0.0011 18.9 0.1 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 KLO04945.1 - 0.00023 20.1 0.4 0.00061 18.7 0.2 1.7 2 0 0 2 2 2 1 FAD binding domain Lycopene_cycl PF05834.7 KLO04945.1 - 0.00077 18.4 0.1 0.0012 17.8 0.1 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_2 PF07992.9 KLO04945.1 - 0.016 15.0 0.0 0.036 13.9 0.0 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 KLO04945.1 - 0.022 14.8 0.0 0.8 9.7 0.0 2.7 2 1 1 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 KLO04945.1 - 0.024 13.0 0.1 0.047 12.1 0.1 1.5 1 0 0 1 1 1 0 HI0933-like protein Thi4 PF01946.12 KLO04945.1 - 0.069 12.2 0.1 0.15 11.1 0.1 1.5 1 0 0 1 1 1 0 Thi4 family GMC_oxred_N PF00732.14 KLO04946.1 - 3.3e-66 223.4 0.0 4.3e-66 223.0 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 KLO04946.1 - 2.1e-36 125.3 0.0 3.8e-36 124.5 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase EF-1_beta_acid PF10587.4 KLO04947.1 - 0.34 11.0 6.2 0.95 9.6 4.3 1.7 1 0 0 1 1 1 0 Eukaryotic elongation factor 1 beta central acidic region F-box-like PF12937.2 KLO04949.1 - 0.00019 21.0 0.0 0.0006 19.4 0.0 1.9 1 0 0 1 1 1 1 F-box-like INSIG PF07281.7 KLO04949.1 - 0.043 13.1 0.1 19 4.4 0.0 3.1 3 0 0 3 3 3 0 Insulin-induced protein (INSIG) DUF948 PF06103.6 KLO04951.1 - 0.00029 20.6 1.9 0.00051 19.8 1.3 1.4 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF948) EzrA PF06160.7 KLO04951.1 - 0.00041 18.6 1.1 0.00055 18.2 0.7 1.1 1 0 0 1 1 1 1 Septation ring formation regulator, EzrA COG6 PF06419.6 KLO04951.1 - 0.0006 18.0 1.6 0.00076 17.7 1.1 1.1 1 0 0 1 1 1 1 Conserved oligomeric complex COG6 COG2 PF06148.6 KLO04951.1 - 0.006 16.4 1.7 0.0094 15.8 1.2 1.2 1 0 0 1 1 1 1 COG (conserved oligomeric Golgi) complex component, COG2 Med9 PF07544.8 KLO04951.1 - 0.018 14.7 1.7 0.03 14.0 1.2 1.4 1 0 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 Reo_sigmaC PF04582.7 KLO04951.1 - 0.029 13.5 0.7 0.035 13.2 0.5 1.1 1 0 0 1 1 1 0 Reovirus sigma C capsid protein DUF3005 PF11448.3 KLO04951.1 - 0.044 13.3 0.0 0.09 12.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3005) Tup_N PF08581.5 KLO04951.1 - 0.12 12.5 0.4 0.18 12.0 0.3 1.2 1 0 0 1 1 1 0 Tup N-terminal DUF972 PF06156.8 KLO04951.1 - 0.17 12.2 0.4 0.27 11.5 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF972) Med4 PF10018.4 KLO04952.1 - 0.0011 18.3 1.4 0.0015 17.9 0.9 1.3 1 0 0 1 1 1 1 Vitamin-D-receptor interacting Mediator subunit 4 DUF2408 PF10303.4 KLO04952.1 - 0.0022 18.1 2.0 0.32 11.1 0.1 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF2408) ATG16 PF08614.6 KLO04952.1 - 0.0032 17.3 0.7 0.0043 16.9 0.5 1.2 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) DUF3450 PF11932.3 KLO04952.1 - 0.0082 15.4 1.0 0.011 15.0 0.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3450) IncA PF04156.9 KLO04952.1 - 0.011 15.3 4.8 0.017 14.7 3.3 1.3 1 0 0 1 1 1 0 IncA protein Adeno_PIX PF03955.9 KLO04952.1 - 0.013 15.9 1.1 0.026 15.0 0.7 1.4 1 0 0 1 1 1 0 Adenovirus hexon-associated protein (IX) OmpH PF03938.9 KLO04952.1 - 0.022 14.7 3.9 0.027 14.3 2.7 1.1 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Syntaxin_2 PF14523.1 KLO04952.1 - 0.041 13.9 0.2 0.061 13.3 0.2 1.2 1 0 0 1 1 1 0 Syntaxin-like protein GP41 PF00517.12 KLO04952.1 - 0.046 13.2 1.3 0.063 12.8 0.9 1.1 1 0 0 1 1 1 0 Retroviral envelope protein DUF869 PF05911.6 KLO04952.1 - 0.061 11.5 5.2 0.077 11.2 3.6 1.0 1 0 0 1 1 1 0 Plant protein of unknown function (DUF869) DUF4140 PF13600.1 KLO04952.1 - 0.066 13.6 2.8 0.11 12.9 1.9 1.3 1 0 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) Cob_adeno_trans PF01923.13 KLO04952.1 - 0.18 11.5 1.2 0.36 10.6 0.3 1.7 1 1 1 2 2 2 0 Cobalamin adenosyltransferase zf-C4H2 PF10146.4 KLO04952.1 - 0.27 11.2 2.5 0.4 10.6 1.7 1.3 1 0 0 1 1 1 0 Zinc finger-containing protein Bap31 PF05529.7 KLO04952.1 - 0.33 10.3 2.5 0.46 9.9 1.7 1.2 1 0 0 1 1 1 0 B-cell receptor-associated protein 31-like TPD52 PF04201.10 KLO04952.1 - 0.37 10.5 4.0 0.59 9.8 2.6 1.6 1 1 0 1 1 1 0 Tumour protein D52 family Lge1 PF11488.3 KLO04952.1 - 0.4 10.8 4.3 1.1 9.5 3.0 2.0 1 1 0 1 1 1 0 Transcriptional regulatory protein LGE1 Prefoldin_2 PF01920.15 KLO04952.1 - 0.48 10.2 6.3 1.1 9.0 4.1 1.7 1 1 1 2 2 2 0 Prefoldin subunit DUF2968 PF11180.3 KLO04952.1 - 0.53 9.6 5.7 0.72 9.1 4.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) APG6 PF04111.7 KLO04952.1 - 0.7 8.8 4.3 0.88 8.5 3.0 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 Spc24 PF08286.6 KLO04952.1 - 1 9.0 5.1 1.2 8.8 2.5 1.7 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 DivIC PF04977.10 KLO04952.1 - 1.9 8.0 5.0 6.2 6.3 3.4 1.9 1 1 0 1 1 1 0 Septum formation initiator Abhydrolase_3 PF07859.8 KLO04953.1 - 4.7e-13 49.2 0.0 5.3e-13 49.0 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF2424 PF10340.4 KLO04953.1 - 1.1e-10 40.6 0.0 1.5e-10 40.3 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2424) Abhydrolase_5 PF12695.2 KLO04953.1 - 0.0018 18.0 0.0 0.0019 17.9 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KLO04953.1 - 0.0093 15.8 0.3 0.01 15.7 0.2 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.15 KLO04953.1 - 0.027 13.8 0.8 3.1 7.1 0.1 2.1 2 0 0 2 2 2 0 Putative esterase Peptidase_S9 PF00326.16 KLO04953.1 - 0.05 12.8 0.0 0.065 12.4 0.0 1.2 1 0 0 1 1 1 0 Prolyl oligopeptidase family Abhydrolase_2 PF02230.11 KLO04953.1 - 0.13 11.7 0.1 0.16 11.3 0.1 1.1 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase PGAP1 PF07819.8 KLO04953.1 - 0.16 11.5 0.0 0.22 11.1 0.0 1.2 1 0 0 1 1 1 0 PGAP1-like protein Peptidase_C12 PF01088.16 KLO04957.1 - 2.8e-16 59.3 0.0 3.3e-16 59.1 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 Med31 PF05669.7 KLO04958.1 - 5.6e-36 122.3 4.3 7.5e-36 121.9 3.0 1.1 1 0 0 1 1 1 1 SOH1 Nod_GRP PF07806.6 KLO04958.1 - 0.0015 18.0 3.7 0.008 15.7 0.1 2.4 2 0 0 2 2 2 1 Nodule-specific GRP repeat Cauli_VI PF01693.11 KLO04960.1 - 0.00019 21.3 0.0 0.00044 20.1 0.0 1.6 1 1 0 1 1 1 1 Caulimovirus viroplasmin peroxidase PF00141.18 KLO04962.1 - 4.5e-27 95.0 0.0 8.4e-27 94.1 0.0 1.5 1 0 0 1 1 1 1 Peroxidase DUF3415 PF11895.3 KLO04962.1 - 5.3e-25 87.0 2.6 1.3e-24 85.8 1.8 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF3415) Cloacin_immun PF03513.9 KLO04962.1 - 0.013 15.5 0.0 0.029 14.4 0.0 1.6 1 0 0 1 1 1 0 Cloacin immunity protein DUF627 PF04781.7 KLO04962.1 - 0.14 11.7 0.0 0.24 11.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF627) RVP PF00077.15 KLO04965.1 - 0.00041 20.2 0.1 0.0012 18.7 0.0 1.7 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.1 KLO04965.1 - 0.0006 20.2 0.0 0.0017 18.8 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease zf-CCHC PF00098.18 KLO04965.1 - 0.001 18.8 0.7 0.0024 17.6 0.5 1.7 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_4 PF14392.1 KLO04965.1 - 0.028 14.0 0.7 0.028 14.0 0.5 1.9 2 0 0 2 2 2 0 Zinc knuckle CDC45 PF02724.9 KLO04965.1 - 0.21 9.5 10.3 0.31 9.0 7.1 1.1 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.7 KLO04965.1 - 0.33 8.8 10.5 0.5 8.2 7.3 1.1 1 0 0 1 1 1 0 Nop14-like family zf-MYND PF01753.13 KLO04974.1 - 2.2e-05 24.2 15.9 7.4e-05 22.5 11.0 1.9 1 1 0 1 1 1 1 MYND finger DZR PF12773.2 KLO04974.1 - 0.46 10.3 8.6 1.3 8.8 6.0 1.8 1 0 0 1 1 1 0 Double zinc ribbon Ecl1 PF12855.2 KLO04974.1 - 6.3 6.1 16.5 37 3.7 11.4 2.3 1 1 0 1 1 1 0 Life-span regulatory factor zf-MYND PF01753.13 KLO04975.1 - 7.3e-07 28.9 10.1 1.5e-06 27.9 7.0 1.5 1 0 0 1 1 1 1 MYND finger IL2 PF00715.12 KLO04976.1 - 0.0012 18.5 0.2 0.0041 16.8 0.0 1.9 2 0 0 2 2 2 1 Interleukin 2 Tol_Tol_Ttg2 PF05494.7 KLO04978.1 - 0.084 12.4 0.0 0.11 12.0 0.0 1.2 1 0 0 1 1 1 0 Toluene tolerance, Ttg2 TraI_2 PF07514.6 KLO04979.1 - 0.11 11.2 0.2 0.14 10.8 0.2 1.1 1 0 0 1 1 1 0 Putative helicase MCM PF00493.18 KLO04981.1 - 0.057 12.2 0.0 0.074 11.8 0.0 1.1 1 0 0 1 1 1 0 MCM2/3/5 family Paralemmin PF03285.10 KLO04982.1 - 0.008 15.6 0.1 0.011 15.2 0.1 1.2 1 0 0 1 1 1 1 Paralemmin Cyclin PF08613.6 KLO04983.1 - 5.2e-07 30.1 0.0 5.2e-07 30.1 0.0 1.0 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.18 KLO04983.1 - 0.00011 21.7 0.0 0.00012 21.6 0.0 1.0 1 0 0 1 1 1 1 Cyclin, N-terminal domain MFS_1 PF07690.11 KLO04984.1 - 8e-18 64.2 14.8 8e-18 64.2 10.2 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily Ribosomal_L18ae PF01775.12 KLO04987.1 - 1e-57 193.3 0.3 1.3e-57 193.0 0.2 1.1 1 0 0 1 1 1 1 Ribosomal L18ae/LX protein domain zf-TRAF PF02176.13 KLO04989.1 - 0.56 10.6 6.3 0.69 10.3 0.4 2.2 2 0 0 2 2 2 0 TRAF-type zinc finger ING PF12998.2 KLO04990.1 - 1.6e-11 44.3 0.1 3e-11 43.5 0.1 1.5 1 0 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.24 KLO04990.1 - 8.1e-10 38.2 7.0 1.3e-09 37.6 4.8 1.3 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.1 KLO04990.1 - 0.032 13.5 0.9 0.057 12.7 0.6 1.4 1 0 0 1 1 1 0 PHD-finger Chitin_synth_2 PF03142.10 KLO04991.1 - 6.8e-282 935.5 0.1 9.1e-282 935.1 0.1 1.1 1 0 0 1 1 1 1 Chitin synthase Glyco_trans_2_3 PF13632.1 KLO04991.1 - 5.7e-17 62.0 0.5 1.4e-16 60.7 0.3 1.7 1 0 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 KLO04991.1 - 6e-15 55.6 0.0 6.5e-14 52.2 0.0 2.4 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.1 KLO04991.1 - 3.6e-05 23.1 0.0 0.0031 16.8 0.0 2.4 2 0 0 2 2 2 1 Glycosyl transferase family 21 Cyt-b5 PF00173.23 KLO04991.1 - 0.00026 20.7 0.0 0.042 13.6 0.0 2.7 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain Glycos_transf_2 PF00535.21 KLO04991.1 - 0.0055 16.3 0.0 0.023 14.3 0.0 2.0 2 0 0 2 2 2 1 Glycosyl transferase family 2 TPR_9 PF13371.1 KLO04992.1 - 0.0047 16.7 2.0 0.011 15.5 0.1 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_11 PF13414.1 KLO04992.1 - 0.035 13.7 0.0 0.41 10.3 0.0 2.7 2 0 0 2 2 2 0 TPR repeat Pkinase_Tyr PF07714.12 KLO04993.1 - 4.7e-23 81.5 0.0 5.2e-23 81.4 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 KLO04993.1 - 1e-22 80.5 0.0 1.2e-22 80.3 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.9 KLO04993.1 - 0.00017 20.7 0.0 0.00022 20.3 0.0 1.1 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 KLO04993.1 - 0.0003 19.8 0.0 0.00036 19.5 0.0 1.0 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 KLO04993.1 - 0.00059 19.6 0.0 0.00063 19.5 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.15 KLO04993.1 - 0.003 16.7 0.0 0.0039 16.3 0.0 1.1 1 0 0 1 1 1 1 Ecdysteroid kinase RIO1 PF01163.17 KLO04993.1 - 0.026 13.8 0.0 0.034 13.4 0.0 1.1 1 0 0 1 1 1 0 RIO1 family NSP2-B_epitope PF14757.1 KLO04993.1 - 0.12 11.8 0.1 0.12 11.8 0.0 1.1 1 0 0 1 1 1 0 Immunogenic region of nsp2 protein of arterivirus polyprotein HTH_29 PF13551.1 KLO04994.1 - 4.4e-10 39.6 0.0 5.7e-10 39.3 0.0 1.1 1 0 0 1 1 1 1 Winged helix-turn helix HTH_32 PF13565.1 KLO04994.1 - 3.2e-08 34.2 0.1 4.6e-08 33.7 0.1 1.2 1 0 0 1 1 1 1 Homeodomain-like domain HTH_23 PF13384.1 KLO04994.1 - 5.1e-05 22.7 0.3 0.0019 17.7 0.0 2.2 2 0 0 2 2 2 1 Homeodomain-like domain HTH_33 PF13592.1 KLO04994.1 - 0.00029 20.3 0.1 0.00063 19.2 0.0 1.6 2 0 0 2 2 2 1 Winged helix-turn helix HTH_Tnp_IS630 PF01710.11 KLO04994.1 - 0.0015 18.2 0.0 0.0027 17.3 0.0 1.4 1 1 0 1 1 1 1 Transposase HTH_28 PF13518.1 KLO04994.1 - 0.0056 16.6 0.2 0.016 15.1 0.0 1.8 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_Tnp_Tc3_2 PF01498.13 KLO04994.1 - 0.0073 16.3 0.0 0.019 14.9 0.0 1.7 2 0 0 2 2 2 1 Transposase FUR PF01475.14 KLO04994.1 - 0.027 14.3 0.0 1.6 8.6 0.0 2.1 2 0 0 2 2 2 0 Ferric uptake regulator family DDE_Tnp_ISAZ013 PF07592.6 KLO04994.1 - 0.081 11.6 0.0 0.1 11.3 0.0 1.1 1 0 0 1 1 1 0 Rhodopirellula transposase DDE domain DDE_3 PF13358.1 KLO04995.1 - 1.2e-10 41.3 0.0 1.3e-10 41.1 0.0 1.0 1 0 0 1 1 1 1 DDE superfamily endonuclease DUF3894 PF13033.1 KLO04995.1 - 0.1 12.6 0.1 0.25 11.3 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3894) DDE_3 PF13358.1 KLO04996.1 - 5.1e-08 32.7 0.0 6.1e-08 32.5 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease Ebola_NP PF05505.7 KLO04997.1 - 4.9 5.0 9.3 8.9 4.2 6.5 1.4 1 0 0 1 1 1 0 Ebola nucleoprotein PH_BEACH PF14844.1 KLO04998.1 - 0.016 15.0 0.0 0.044 13.6 0.0 1.7 1 0 0 1 1 1 0 PH domain associated with Beige/BEACH DUF2205 PF10224.4 KLO04998.1 - 0.036 13.6 1.2 0.11 12.0 0.8 1.8 1 1 0 1 1 1 0 Predicted coiled-coil protein (DUF2205) D5_N PF08706.6 KLO04998.1 - 0.072 13.1 0.5 0.32 11.0 0.0 2.3 2 0 0 2 2 2 0 D5 N terminal like Pkinase PF00069.20 KLO04999.1 - 0.011 14.8 0.0 0.013 14.6 0.0 1.0 1 0 0 1 1 1 0 Protein kinase domain Pkinase_Tyr PF07714.12 KLO04999.1 - 0.028 13.5 0.0 0.033 13.2 0.0 1.0 1 0 0 1 1 1 0 Protein tyrosine kinase Zn_clus PF00172.13 KLO05000.1 - 0.87 9.5 14.4 1.2 9.1 3.0 2.2 2 0 0 2 2 2 0 Fungal Zn(2)-Cys(6) binuclear cluster domain DEAD PF00270.24 KLO05001.1 - 1.5e-48 164.4 0.0 1.1e-46 158.4 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KLO05001.1 - 2.8e-28 97.5 0.0 5.8e-28 96.5 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 KLO05001.1 - 8.1e-07 29.0 0.0 2.2e-06 27.6 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C_2 PF13307.1 KLO05001.1 - 0.0074 16.2 0.0 0.013 15.4 0.0 1.3 1 0 0 1 1 1 1 Helicase C-terminal domain DUF1253 PF06862.7 KLO05001.1 - 0.012 14.1 0.0 0.14 10.5 0.0 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF1253) AAA_30 PF13604.1 KLO05001.1 - 0.018 14.6 0.0 0.2 11.2 0.0 2.5 2 1 0 2 2 2 0 AAA domain GRP PF07172.6 KLO05001.1 - 0.024 15.1 11.2 0.024 15.1 7.8 2.5 2 0 0 2 2 2 0 Glycine rich protein family DUF2443 PF10398.4 KLO05001.1 - 0.15 11.8 0.3 0.45 10.3 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2443) zf-MYND PF01753.13 KLO05002.1 - 3.6e-07 29.9 15.1 7.2e-07 28.9 10.5 1.5 1 0 0 1 1 1 1 MYND finger zf-Mss51 PF13824.1 KLO05002.1 - 0.006 16.4 2.7 0.016 15.0 1.9 1.7 1 0 0 1 1 1 1 Zinc-finger of mitochondrial splicing suppressor 51 zf-MYND PF01753.13 KLO05003.1 - 1.4e-08 34.4 9.5 2.8e-08 33.5 6.6 1.5 1 0 0 1 1 1 1 MYND finger E1-E2_ATPase PF00122.15 KLO05005.1 - 3.4e-25 88.4 0.3 1.3e-24 86.5 0.0 2.1 3 0 0 3 3 3 1 E1-E2 ATPase Hydrolase PF00702.21 KLO05005.1 - 3.1e-22 80.0 0.0 7.1e-22 78.8 0.0 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 KLO05005.1 - 8.3e-21 75.0 0.0 1.5e-20 74.1 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 KLO05005.1 - 8.8e-05 22.3 0.0 0.00019 21.3 0.0 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Cation_ATPase_N PF00690.21 KLO05005.1 - 0.011 15.2 0.0 0.033 13.6 0.0 1.9 1 0 0 1 1 1 0 Cation transporter/ATPase, N-terminus P5-ATPase PF12409.3 KLO05005.1 - 0.053 13.3 0.0 0.053 13.3 0.0 3.0 3 0 0 3 3 3 0 P5-type ATPase cation transporter Hydrolase_3 PF08282.7 KLO05005.1 - 0.086 12.3 0.0 0.19 11.2 0.0 1.5 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase Hydantoinase_B PF02538.9 KLO05006.1 - 1.6e-185 617.3 0.0 2.6e-179 596.8 0.0 2.0 2 0 0 2 2 2 2 Hydantoinase B/oxoprolinase EF-hand_1 PF00036.27 KLO05007.1 - 4.7e-42 138.0 9.8 5e-10 37.9 0.0 4.1 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.1 KLO05007.1 - 2.9e-37 126.6 2.1 1.1e-19 70.3 0.1 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.1 KLO05007.1 - 2.5e-34 116.6 9.6 4.4e-16 58.2 0.1 4.1 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_6 PF13405.1 KLO05007.1 - 2.6e-31 104.6 5.6 1.2e-09 37.2 0.1 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.1 KLO05007.1 - 1.1e-28 97.2 5.5 4e-07 29.0 0.0 4.3 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.1 KLO05007.1 - 9.6e-14 51.0 0.1 2.2e-08 33.9 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.2 KLO05007.1 - 2.9e-09 36.5 0.4 0.0003 20.4 0.0 2.4 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.4 KLO05007.1 - 4.9e-09 36.2 0.0 0.00051 20.0 0.0 2.1 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region UPF0154 PF03672.8 KLO05007.1 - 1.1e-07 31.3 0.0 0.014 14.9 0.0 3.3 2 1 1 3 3 3 2 Uncharacterised protein family (UPF0154) EFhand_Ca_insen PF08726.5 KLO05007.1 - 9.3e-06 25.5 0.7 0.00011 22.1 0.1 2.3 2 1 0 2 2 2 1 Ca2+ insensitive EF hand Caleosin PF05042.8 KLO05007.1 - 0.00013 21.5 0.1 0.038 13.5 0.0 2.4 1 1 0 2 2 2 1 Caleosin related protein DUF1103 PF06513.6 KLO05007.1 - 0.00046 19.6 0.6 0.00049 19.5 0.4 1.1 1 0 0 1 1 1 1 Repeat of unknown function (DUF1103) MotA_activ PF09114.5 KLO05007.1 - 0.0057 16.3 0.1 1.1 9.0 0.0 2.3 2 0 0 2 2 2 1 Transcription factor MotA, activation domain Poly_export PF02563.11 KLO05007.1 - 0.012 15.3 0.1 1.7 8.4 0.0 3.0 1 1 1 2 2 2 0 Polysaccharide biosynthesis/export protein TerB PF05099.8 KLO05007.1 - 0.017 14.8 0.2 0.34 10.6 0.0 2.2 1 1 1 2 2 2 0 Tellurite resistance protein TerB RNA_pol_Rpb4 PF03874.11 KLO05007.1 - 0.036 14.0 1.0 7.1 6.6 0.0 2.5 3 0 0 3 3 3 0 RNA polymerase Rpb4 LNS2 PF08235.8 KLO05007.1 - 0.038 13.5 0.0 0.47 10.0 0.0 2.0 2 0 0 2 2 2 0 LNS2 (Lipin/Ned1/Smp2) DUF853 PF05872.7 KLO05007.1 - 0.091 11.0 0.0 4 5.6 0.0 2.0 1 1 0 2 2 2 0 Bacterial protein of unknown function (DUF853) Tenui_NCP PF04876.7 KLO05007.1 - 0.11 12.0 0.0 0.9 9.0 0.0 2.0 1 1 1 2 2 2 0 Tenuivirus major non-capsid protein VCBS PF13517.1 KLO05007.1 - 1.4 9.3 5.6 9.1 6.7 0.2 2.5 2 2 0 2 2 2 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella Ribosomal_S7e PF01251.13 KLO05010.1 - 3.1e-79 264.8 3.8 3.4e-79 264.7 2.6 1.0 1 0 0 1 1 1 1 Ribosomal protein S7e Abhydrolase_6 PF12697.2 KLO05011.1 - 9.2e-17 61.6 0.9 1.1e-16 61.3 0.2 1.5 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KLO05011.1 - 5.3e-07 29.4 0.0 1.1e-06 28.4 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KLO05011.1 - 0.018 14.7 0.0 0.035 13.8 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family Bystin PF05291.6 KLO05012.1 - 8.9e-121 402.4 0.0 1.4e-120 401.8 0.0 1.2 1 0 0 1 1 1 1 Bystin DUF3245 PF11595.3 KLO05012.1 - 0.2 11.9 6.3 0.38 11.0 4.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3245) Epimerase PF01370.16 KLO05013.1 - 4.6e-43 147.3 0.0 5.7e-43 147.0 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 KLO05013.1 - 2.4e-09 36.5 0.0 2.6e-05 23.2 0.0 2.2 2 0 0 2 2 2 2 Male sterility protein 3Beta_HSD PF01073.14 KLO05013.1 - 2.9e-07 29.4 0.0 4.8e-07 28.7 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.12 KLO05013.1 - 1.1e-05 24.5 0.0 1.6e-05 23.9 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_10 PF13460.1 KLO05013.1 - 5e-05 23.3 0.0 7.7e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding Polysacc_synt_2 PF02719.10 KLO05013.1 - 6.8e-05 21.9 0.1 0.001 18.0 0.0 2.3 2 1 0 2 2 2 1 Polysaccharide biosynthesis protein adh_short PF00106.20 KLO05013.1 - 0.049 13.5 0.1 0.12 12.3 0.1 1.6 1 0 0 1 1 1 0 short chain dehydrogenase MRP-S27 PF10037.4 KLO05015.1 - 0.074 11.9 0.1 0.11 11.3 0.1 1.3 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S27 DDE_Tnp_4 PF13359.1 KLO05016.1 - 0.0011 18.6 0.1 0.002 17.7 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease Spt5_N PF11942.3 KLO05016.1 - 0.063 13.9 7.1 0.16 12.6 4.9 1.6 1 1 0 1 1 1 0 Spt5 transcription elongation factor, acidic N-terminal DUF4419 PF14388.1 KLO05017.1 - 5.4e-09 35.6 1.4 7.4e-09 35.2 0.0 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4419) Lactamase_B_2 PF12706.2 KLO05018.1 - 0.0084 15.6 0.0 0.016 14.7 0.0 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain zf-C2HC5 PF06221.8 KLO05018.1 - 0.0098 15.6 0.1 0.024 14.4 0.0 1.5 1 0 0 1 1 1 1 Putative zinc finger motif, C2HC5-type Herpes_UL45 PF05473.7 KLO05019.1 - 0.0065 15.9 0.2 0.0086 15.5 0.1 1.2 1 0 0 1 1 1 1 UL45 protein Med15 PF09606.5 KLO05021.1 - 0.9 7.6 94.8 1.1 7.3 65.7 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Fungal_trans PF04082.13 KLO05022.1 - 1.3e-20 73.4 0.5 1.8e-20 72.8 0.3 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain CaATP_NAI PF12515.3 KLO05024.1 - 0.021 14.3 0.4 0.039 13.4 0.3 1.6 1 0 0 1 1 1 0 Ca2+-ATPase N terminal autoinhibitory domain MFS_1 PF07690.11 KLO05029.1 - 7.4e-16 57.7 34.0 7.4e-16 57.7 23.6 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily UNC-93 PF05978.11 KLO05029.1 - 4.3e-11 42.5 5.1 4.3e-11 42.5 3.6 2.5 2 0 0 2 2 2 1 Ion channel regulatory protein UNC-93 Dexa_ind PF15198.1 KLO05029.1 - 0.068 13.0 0.0 0.28 11.0 0.0 2.0 2 0 0 2 2 2 0 Dexamethasone-induced zf-LITAF-like PF10601.4 KLO05029.1 - 0.13 12.1 4.8 0.37 10.6 0.0 3.3 3 0 0 3 3 3 0 LITAF-like zinc ribbon domain His_Phos_2 PF00328.17 KLO05030.1 - 6.8e-53 180.2 0.0 8.3e-53 179.9 0.0 1.0 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) DDE_3 PF13358.1 KLO05031.1 - 1.1e-09 38.1 0.7 8.9e-09 35.2 0.5 2.2 1 1 0 1 1 1 1 DDE superfamily endonuclease F-box-like PF12937.2 KLO05033.1 - 5.3e-10 38.8 0.0 2.2e-09 36.8 0.0 2.2 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KLO05033.1 - 7.8e-05 22.2 0.0 0.00028 20.4 0.0 2.0 1 0 0 1 1 1 1 F-box domain DUF1648 PF07853.6 KLO05034.1 - 0.14 11.6 0.0 3.5 7.2 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1648) F-box-like PF12937.2 KLO05035.1 - 1.4e-05 24.7 0.0 2.4e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KLO05035.1 - 0.0038 16.8 0.1 0.0079 15.8 0.0 1.6 1 0 0 1 1 1 1 F-box domain Exo_endo_phos PF03372.18 KLO05038.1 - 7.1e-14 52.3 0.0 8.3e-14 52.1 0.0 1.1 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family UBX PF00789.15 KLO05040.1 - 3.3e-10 39.8 0.4 6.4e-10 38.9 0.0 1.7 2 0 0 2 2 2 1 UBX domain UBA PF00627.26 KLO05040.1 - 0.0015 18.2 0.1 0.0047 16.7 0.1 1.9 1 0 0 1 1 1 1 UBA/TS-N domain CDK5_activator PF03261.10 KLO05040.1 - 0.014 14.7 5.2 0.021 14.1 3.6 1.1 1 0 0 1 1 1 0 Cyclin-dependent kinase 5 activator protein DUF4402 PF14352.1 KLO05040.1 - 0.016 15.6 0.7 0.032 14.6 0.5 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4402) DUF572 PF04502.8 KLO05040.1 - 0.083 12.1 13.3 0.11 11.6 9.2 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) zf-C2H2_2 PF12756.2 KLO05040.1 - 0.14 12.3 0.4 0.29 11.2 0.3 1.6 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) Lipoprotein_X PF03305.8 KLO05040.1 - 5.4 6.3 8.3 8.3 5.7 5.7 1.2 1 0 0 1 1 1 0 Mycoplasma MG185/MG260 protein Helicase_C_3 PF13625.1 KLO05041.1 - 4.5e-26 91.1 0.0 2.3e-25 88.8 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain SNF2_N PF00176.18 KLO05041.1 - 1.4e-14 53.6 0.1 2e-14 53.1 0.1 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain ResIII PF04851.10 KLO05041.1 - 7.4e-14 51.9 0.0 1.7e-13 50.8 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.26 KLO05041.1 - 1.8e-12 46.9 0.0 5.1e-12 45.4 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 KLO05041.1 - 1.7e-07 30.8 0.1 4.7e-07 29.4 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase RNase_H PF00075.19 KLO05042.1 - 3.2e-26 92.2 0.2 4.3e-26 91.8 0.2 1.1 1 0 0 1 1 1 1 RNase H RVT_1 PF00078.22 KLO05043.1 - 4.1e-06 26.3 0.0 6.6e-06 25.6 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_1 PF00078.22 KLO05044.1 - 7.4e-05 22.2 0.0 0.00014 21.3 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) F-box-like PF12937.2 KLO05049.1 - 8.5e-05 22.2 0.1 0.00018 21.1 0.1 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KLO05049.1 - 0.0051 16.4 0.1 0.01 15.4 0.0 1.6 1 0 0 1 1 1 1 F-box domain HxlR PF01638.12 KLO05049.1 - 0.052 13.1 0.0 0.16 11.6 0.0 1.7 2 0 0 2 2 2 0 HxlR-like helix-turn-helix DUF4243 PF14027.1 KLO05052.1 - 1.7e-86 290.7 0.0 2e-86 290.4 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4243) DUF4243 PF14027.1 KLO05053.1 - 5.7e-81 272.5 0.0 6.9e-81 272.2 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4243) FA_hydroxylase PF04116.8 KLO05056.1 - 1.2e-13 51.5 20.8 1.2e-13 51.5 14.4 1.8 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily Tet_JBP PF12851.2 KLO05058.1 - 1.5e-06 27.6 0.0 2e-06 27.2 0.0 1.1 1 0 0 1 1 1 1 Oxygenase domain of the 2OGFeDO superfamily zf-UDP PF14569.1 KLO05059.1 - 3.4 7.4 10.0 1.5 8.6 1.1 3.3 2 0 0 2 2 2 0 Zinc-binding RING-finger Helicase_C PF00271.26 KLO05062.1 - 1.3e-15 56.9 0.0 3.9e-15 55.4 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 KLO05062.1 - 4.9e-14 52.1 0.0 7.8e-14 51.5 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.10 KLO05062.1 - 4e-05 23.5 0.2 0.00017 21.5 0.0 2.0 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit SNF2_N PF00176.18 KLO05062.1 - 0.0065 15.2 0.0 0.011 14.5 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain DUF4658 PF15555.1 KLO05063.1 - 0.0045 16.8 0.1 0.011 15.6 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4658) Cauli_VI PF01693.11 KLO05065.1 - 7.5e-07 29.0 0.1 1.3e-06 28.2 0.1 1.4 1 0 0 1 1 1 1 Caulimovirus viroplasmin DUF3493 PF11998.3 KLO05067.1 - 0.0094 15.8 0.1 0.026 14.3 0.1 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF3493) Desmo_N PF06771.6 KLO05068.1 - 0.099 12.5 0.2 0.16 11.8 0.1 1.5 1 0 0 1 1 1 0 Viral Desmoplakin N-terminus Orbi_VP2 PF00898.12 KLO05070.1 - 0.11 9.9 0.0 0.14 9.6 0.0 1.0 1 0 0 1 1 1 0 Orbivirus outer capsid protein VP2 Form_Nir_trans PF01226.12 KLO05075.1 - 1.3e-61 207.7 19.5 1.6e-61 207.3 13.5 1.0 1 0 0 1 1 1 1 Formate/nitrite transporter CP12 PF02672.10 KLO05076.1 - 0.062 13.7 0.0 0.12 12.8 0.0 1.3 1 0 0 1 1 1 0 CP12 domain Pkinase PF00069.20 KLO05077.1 - 7.8e-29 100.6 0.0 1.1e-24 87.0 0.0 2.8 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 KLO05077.1 - 8.5e-12 44.6 0.4 4.3e-05 22.7 0.0 3.7 3 1 1 4 4 4 3 Protein tyrosine kinase APH PF01636.18 KLO05077.1 - 0.059 13.0 0.0 0.26 11.0 0.0 1.9 2 0 0 2 2 2 0 Phosphotransferase enzyme family Lipase_3 PF01764.20 KLO05078.1 - 9.2e-33 112.8 0.1 1.3e-32 112.3 0.1 1.2 1 0 0 1 1 1 1 Lipase (class 3) Cutinase PF01083.17 KLO05078.1 - 0.00053 19.7 0.0 0.00085 19.0 0.0 1.3 1 0 0 1 1 1 1 Cutinase Lipase3_N PF03893.11 KLO05078.1 - 0.0093 15.7 0.0 0.059 13.1 0.0 2.1 2 0 0 2 2 2 1 Lipase 3 N-terminal region Lipase_3 PF01764.20 KLO05079.1 - 2.9e-32 111.2 0.0 5.2e-32 110.3 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) Cutinase PF01083.17 KLO05079.1 - 0.082 12.6 0.0 0.16 11.6 0.0 1.4 1 0 0 1 1 1 0 Cutinase DUF2401 PF10287.4 KLO05080.1 - 0.1 12.0 0.1 0.11 11.9 0.1 1.0 1 0 0 1 1 1 0 Putative TOS1-like glycosyl hydrolase (DUF2401) NIPSNAP PF07978.8 KLO05083.1 - 0.0073 16.2 0.0 0.016 15.1 0.0 1.5 1 0 0 1 1 1 1 NIPSNAP Lipase_3 PF01764.20 KLO05084.1 - 4.9e-33 113.7 0.0 7.4e-33 113.1 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) Cutinase PF01083.17 KLO05084.1 - 0.017 14.9 0.1 0.031 14.0 0.0 1.5 1 1 0 1 1 1 0 Cutinase Lipase3_N PF03893.11 KLO05084.1 - 0.092 12.5 0.0 0.21 11.4 0.0 1.6 1 0 0 1 1 1 0 Lipase 3 N-terminal region Lipase_3 PF01764.20 KLO05085.1 - 9.2e-33 112.8 0.1 1.3e-32 112.3 0.1 1.2 1 0 0 1 1 1 1 Lipase (class 3) Cutinase PF01083.17 KLO05085.1 - 0.00053 19.7 0.0 0.00085 19.0 0.0 1.3 1 0 0 1 1 1 1 Cutinase Lipase3_N PF03893.11 KLO05085.1 - 0.0093 15.7 0.0 0.059 13.1 0.0 2.1 2 0 0 2 2 2 1 Lipase 3 N-terminal region Pkinase PF00069.20 KLO05086.1 - 7.8e-29 100.6 0.0 1.1e-24 87.0 0.0 2.8 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 KLO05086.1 - 8.5e-12 44.6 0.4 4.3e-05 22.7 0.0 3.7 3 1 1 4 4 4 3 Protein tyrosine kinase APH PF01636.18 KLO05086.1 - 0.059 13.0 0.0 0.26 11.0 0.0 1.9 2 0 0 2 2 2 0 Phosphotransferase enzyme family CP12 PF02672.10 KLO05087.1 - 0.062 13.7 0.0 0.12 12.8 0.0 1.3 1 0 0 1 1 1 0 CP12 domain Form_Nir_trans PF01226.12 KLO05088.1 - 1.3e-61 207.7 19.5 1.6e-61 207.3 13.5 1.0 1 0 0 1 1 1 1 Formate/nitrite transporter Ras PF00071.17 KLO05097.1 - 4.8e-54 182.1 0.0 5.6e-54 181.9 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KLO05097.1 - 1.1e-14 54.9 0.0 1.7e-14 54.3 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KLO05097.1 - 8.2e-09 34.9 0.0 1.2e-08 34.3 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 KLO05097.1 - 0.0063 15.7 0.0 0.0088 15.2 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.7 KLO05097.1 - 0.015 14.4 0.0 0.019 14.1 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region PduV-EutP PF10662.4 KLO05097.1 - 0.06 12.8 0.1 12 5.3 0.0 2.6 2 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation F-box-like PF12937.2 KLO05100.1 - 0.0014 18.2 2.0 0.0025 17.4 0.6 2.2 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 KLO05100.1 - 0.0018 17.8 0.0 0.0066 16.0 0.0 2.0 1 0 0 1 1 1 1 F-box domain Nse4_C PF08743.5 KLO05101.1 - 1.4e-25 89.0 0.1 3.3e-25 87.9 0.0 1.7 1 0 0 1 1 1 1 Nse4 C-terminal Nse4-Nse3_bdg PF15412.1 KLO05101.1 - 2.9e-18 65.4 0.3 7.9e-18 64.0 0.2 1.8 1 0 0 1 1 1 1 Binding domain of Nse4/EID3 to Nse3-MAGE CENP-K PF11802.3 KLO05101.1 - 0.004 16.4 0.3 0.0086 15.3 0.1 1.6 1 1 0 1 1 1 1 Centromere-associated protein K Proteasome PF00227.21 KLO05102.1 - 5.4e-53 179.1 0.1 1e-52 178.2 0.1 1.4 1 1 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 KLO05102.1 - 9.6e-15 53.5 0.2 1.8e-14 52.7 0.1 1.5 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature DUF348 PF03990.9 KLO05102.1 - 0.37 10.4 1.7 1.1 8.8 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF348) CHZ PF09649.5 KLO05104.1 - 0.0058 15.8 0.4 0.0058 15.8 0.3 2.7 2 1 0 2 2 1 1 Histone chaperone domain CHZ Cwf_Cwc_15 PF04889.7 KLO05104.1 - 0.0079 15.9 18.8 0.009 15.7 13.0 1.1 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein DUF2457 PF10446.4 KLO05104.1 - 0.077 11.7 20.1 0.074 11.7 13.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) NOA36 PF06524.7 KLO05104.1 - 0.16 11.1 14.1 0.2 10.8 9.8 1.1 1 0 0 1 1 1 0 NOA36 protein Vfa1 PF08432.5 KLO05104.1 - 0.17 11.9 13.0 0.19 11.7 9.0 1.2 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Pox_Ag35 PF03286.9 KLO05104.1 - 0.18 11.3 10.2 0.21 11.1 7.1 1.3 1 0 0 1 1 1 0 Pox virus Ag35 surface protein CDC27 PF09507.5 KLO05104.1 - 0.28 10.3 22.5 0.33 10.1 15.6 1.0 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Daxx PF03344.10 KLO05104.1 - 0.33 9.3 21.9 0.35 9.2 15.2 1.1 1 0 0 1 1 1 0 Daxx Family MIP-T3 PF10243.4 KLO05104.1 - 0.7 8.2 19.3 0.73 8.2 13.4 1.0 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 DDRGK PF09756.4 KLO05104.1 - 0.73 9.2 13.4 0.83 9.0 9.3 1.2 1 0 0 1 1 1 0 DDRGK domain RNA_pol_3_Rpc31 PF11705.3 KLO05104.1 - 0.78 9.6 21.1 1.3 8.8 14.6 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 Nop14 PF04147.7 KLO05104.1 - 1 7.1 23.8 1.1 7.1 16.5 1.0 1 0 0 1 1 1 0 Nop14-like family GCIP PF13324.1 KLO05104.1 - 1.3 8.1 6.3 1.5 7.9 4.4 1.1 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting FAM176 PF14851.1 KLO05104.1 - 1.7 8.3 12.0 2.7 7.6 8.1 1.5 1 1 0 1 1 1 0 FAM176 family FLO_LFY PF01698.11 KLO05104.1 - 2.2 7.0 10.8 2.4 6.9 7.5 1.2 1 0 0 1 1 1 0 Floricaula / Leafy protein CDC45 PF02724.9 KLO05104.1 - 2.4 6.0 17.4 2.7 5.9 12.1 1.1 1 0 0 1 1 1 0 CDC45-like protein IFT57 PF10498.4 KLO05104.1 - 2.4 6.7 8.6 2.8 6.5 6.0 1.1 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 DTHCT PF08070.6 KLO05104.1 - 2.7 8.6 11.2 1.3 9.7 5.8 1.9 1 1 1 2 2 2 0 DTHCT (NUC029) region DUF1510 PF07423.6 KLO05104.1 - 3 7.1 19.5 3.8 6.8 13.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Retinal PF15449.1 KLO05104.1 - 3.2 5.2 9.6 3.9 4.9 6.7 1.2 1 0 0 1 1 1 0 Retinal protein TRAP_alpha PF03896.11 KLO05104.1 - 4.7 6.1 12.1 5.1 5.9 8.4 1.3 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit BUD22 PF09073.5 KLO05104.1 - 6.9 5.6 22.1 6.9 5.6 15.3 1.1 1 0 0 1 1 1 0 BUD22 BTV_NS2 PF04514.7 KLO05104.1 - 7.2 5.3 10.4 8.2 5.1 7.2 1.2 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 Astro_capsid PF03115.9 KLO05104.1 - 8.4 4.5 6.6 8.8 4.4 4.6 1.1 1 0 0 1 1 1 0 Astrovirus capsid protein precursor bZIP_2 PF07716.10 KLO05105.1 - 2.8e-11 43.0 10.7 2.8e-11 43.0 7.4 2.9 3 0 0 3 3 2 1 Basic region leucine zipper bZIP_1 PF00170.16 KLO05105.1 - 1.3e-09 37.8 17.6 1.5e-09 37.6 6.3 2.6 2 0 0 2 2 2 1 bZIP transcription factor Borrelia_P83 PF05262.6 KLO05105.1 - 0.00074 17.9 0.6 0.00091 17.6 0.4 1.1 1 0 0 1 1 1 1 Borrelia P83/100 protein CAF-1_p150 PF11600.3 KLO05105.1 - 0.0032 16.8 12.9 0.0032 16.8 8.9 1.9 2 0 0 2 2 2 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal Fmp27_WPPW PF10359.4 KLO05105.1 - 0.041 12.2 6.6 0.057 11.8 4.6 1.2 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain IncA PF04156.9 KLO05105.1 - 0.045 13.3 5.7 0.081 12.5 4.0 1.4 1 0 0 1 1 1 0 IncA protein Dynactin_p22 PF07426.6 KLO05105.1 - 0.075 12.3 0.4 0.14 11.4 0.2 1.4 1 0 0 1 1 1 0 Dynactin subunit p22 WD40_alt PF14077.1 KLO05105.1 - 0.17 11.5 0.3 0.17 11.5 0.2 2.2 2 0 0 2 2 2 0 Alternative WD40 repeat motif RGS-like PF09128.6 KLO05105.1 - 0.88 9.0 4.9 0.32 10.4 1.6 1.6 2 0 0 2 2 2 0 Regulator of G protein signalling-like domain DUF4407 PF14362.1 KLO05105.1 - 1.1 8.1 8.8 1.5 7.6 6.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) HAUS6_N PF14661.1 KLO05105.1 - 1.1 8.5 9.4 2.3 7.5 6.5 1.5 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus V_ATPase_I PF01496.14 KLO05105.1 - 1.4 6.6 4.0 1.9 6.2 2.7 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF342 PF03961.8 KLO05105.1 - 1.8 6.8 4.6 2.4 6.4 3.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) TSC22 PF01166.13 KLO05105.1 - 2.3 8.2 6.0 2.2 8.3 0.3 2.4 1 1 2 3 3 3 0 TSC-22/dip/bun family AAA_23 PF13476.1 KLO05105.1 - 4.5 7.5 6.4 6.2 7.0 4.4 1.2 1 0 0 1 1 1 0 AAA domain DUF972 PF06156.8 KLO05105.1 - 5 7.5 7.2 10 6.5 4.1 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF972) bZIP_Maf PF03131.12 KLO05105.1 - 7.1 7.0 24.6 0.048 13.9 9.4 2.7 2 1 1 3 3 3 0 bZIP Maf transcription factor Mnd1 PF03962.10 KLO05105.1 - 7.6 6.1 13.8 17 4.9 9.6 1.6 1 1 0 1 1 1 0 Mnd1 family DUF904 PF06005.7 KLO05105.1 - 8.5 6.7 15.2 0.14 12.4 5.0 2.2 3 0 0 3 3 1 0 Protein of unknown function (DUF904) DUF1793 PF08760.6 KLO05108.1 - 2.4e-31 108.8 0.0 4.1e-31 108.1 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1793) Bac_rhamnosid PF05592.6 KLO05108.1 - 0.00055 18.2 0.0 0.00083 17.6 0.0 1.2 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase Metallophos PF00149.23 KLO05110.1 - 9.1e-10 38.2 1.5 4.5e-09 35.9 1.0 2.2 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 KLO05110.1 - 0.0012 18.6 0.0 0.0041 16.9 0.0 1.9 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain F-box-like PF12937.2 KLO05111.1 - 1.1e-07 31.5 0.1 2.8e-07 30.1 0.1 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KLO05111.1 - 0.017 14.7 2.9 2.5 7.8 0.2 3.5 3 0 0 3 3 3 0 F-box domain DAO PF01266.19 KLO05118.1 - 9.4e-48 162.9 0.3 1.4e-47 162.3 0.2 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KLO05118.1 - 6.7e-05 22.8 0.2 0.00024 21.0 0.1 1.8 1 1 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 KLO05118.1 - 0.011 15.6 2.5 0.46 10.3 0.6 2.5 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 KLO05118.1 - 0.012 14.6 0.5 0.023 13.7 0.4 1.4 1 0 0 1 1 1 0 Thi4 family Pyr_redox PF00070.22 KLO05118.1 - 0.017 15.4 0.4 0.036 14.4 0.3 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 KLO05118.1 - 0.049 12.2 0.1 0.058 12.0 0.1 1.2 1 0 0 1 1 1 0 Tryptophan halogenase GIDA PF01134.17 KLO05118.1 - 0.051 12.4 0.1 3.6 6.3 0.0 2.1 2 0 0 2 2 2 0 Glucose inhibited division protein A NADH_u_ox_C PF12853.2 KLO05124.1 - 0.14 11.8 0.0 0.42 10.3 0.0 1.8 1 0 0 1 1 1 0 C-terminal of NADH-ubiquinone oxidoreductase 21 kDa subunit DDE_3 PF13358.1 KLO05127.1 - 0.055 13.2 0.0 0.064 12.9 0.0 1.2 1 0 0 1 1 1 0 DDE superfamily endonuclease Dimer_Tnp_hAT PF05699.9 KLO05129.1 - 4.2e-05 23.0 0.0 8.8e-05 22.0 0.0 1.6 1 1 0 1 1 1 1 hAT family C-terminal dimerisation region CHASE PF03924.8 KLO05129.1 - 0.0036 16.5 0.0 0.015 14.4 0.0 1.8 1 1 0 1 1 1 1 CHASE domain TIP_N PF12457.3 KLO05130.1 - 0.18 11.8 0.1 0.18 11.8 0.1 1.8 2 0 0 2 2 2 0 Tuftelin interacting protein N terminal AAA_16 PF13191.1 KLO05131.1 - 3.8e-09 36.7 0.2 0.0037 17.2 0.0 3.8 4 1 0 4 4 3 2 AAA ATPase domain AAA_22 PF13401.1 KLO05131.1 - 5.1e-08 33.1 0.0 0.00051 20.1 0.0 3.3 2 0 0 2 2 2 2 AAA domain AAA_17 PF13207.1 KLO05131.1 - 8.7e-08 33.0 0.2 0.011 16.5 0.0 3.6 2 1 0 2 2 2 2 AAA domain NACHT PF05729.7 KLO05131.1 - 1.3e-07 31.4 0.6 0.00071 19.2 0.0 3.6 2 1 0 2 2 2 2 NACHT domain Zeta_toxin PF06414.7 KLO05131.1 - 4.4e-07 29.1 0.0 0.0019 17.3 0.0 2.5 2 0 0 2 2 2 2 Zeta toxin NB-ARC PF00931.17 KLO05131.1 - 8.5e-07 28.0 0.0 0.00048 19.0 0.0 3.1 3 0 0 3 3 3 1 NB-ARC domain AAA PF00004.24 KLO05131.1 - 1.7e-06 28.2 0.1 0.0031 17.7 0.0 3.7 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.1 KLO05131.1 - 2.2e-06 27.6 0.0 0.044 13.6 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.1 KLO05131.1 - 4.7e-06 26.1 0.1 0.045 13.1 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_14 PF13173.1 KLO05131.1 - 2.6e-05 24.1 0.0 0.47 10.3 0.0 3.7 2 1 0 2 2 2 1 AAA domain AAA_18 PF13238.1 KLO05131.1 - 3e-05 24.3 0.0 0.35 11.1 0.0 3.2 2 1 0 2 2 2 2 AAA domain AAA_19 PF13245.1 KLO05131.1 - 3e-05 23.6 0.0 0.12 12.1 0.0 2.7 2 0 0 2 2 2 2 Part of AAA domain RNA_helicase PF00910.17 KLO05131.1 - 5.3e-05 23.3 0.0 0.24 11.6 0.0 2.7 2 0 0 2 2 2 2 RNA helicase PPV_E1_C PF00519.12 KLO05131.1 - 0.00015 20.5 0.0 0.38 9.2 0.0 2.6 3 0 0 3 3 3 2 Papillomavirus helicase DUF2075 PF09848.4 KLO05131.1 - 0.00023 20.2 0.1 0.21 10.4 0.0 2.4 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2075) ResIII PF04851.10 KLO05131.1 - 0.0003 20.6 0.1 0.045 13.5 0.0 2.8 3 0 0 3 3 2 1 Type III restriction enzyme, res subunit ABC_tran PF00005.22 KLO05131.1 - 0.00034 20.9 0.4 0.55 10.5 0.1 3.4 3 1 0 3 3 2 1 ABC transporter Parvo_NS1 PF01057.12 KLO05131.1 - 0.00039 19.3 0.1 0.13 11.1 0.0 2.4 2 0 0 2 2 2 1 Parvovirus non-structural protein NS1 APS_kinase PF01583.15 KLO05131.1 - 0.00041 20.0 0.9 1.2 8.8 0.0 3.3 3 0 0 3 3 3 2 Adenylylsulphate kinase MobB PF03205.9 KLO05131.1 - 0.0016 18.1 0.1 0.41 10.3 0.0 2.6 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_PrkA PF08298.6 KLO05131.1 - 0.0016 17.1 0.0 0.077 11.6 0.0 2.4 2 0 0 2 2 2 1 PrkA AAA domain FtsK_SpoIIIE PF01580.13 KLO05131.1 - 0.0026 17.2 0.1 6.2 6.2 0.0 3.3 3 0 0 3 3 3 0 FtsK/SpoIIIE family TIP49 PF06068.8 KLO05131.1 - 0.0028 16.4 0.1 0.066 11.9 0.0 2.3 2 0 0 2 2 2 1 TIP49 C-terminus IstB_IS21 PF01695.12 KLO05131.1 - 0.0032 16.9 0.1 1.9 7.8 0.0 2.6 2 0 0 2 2 2 1 IstB-like ATP binding protein SMC_N PF02463.14 KLO05131.1 - 0.0063 15.7 0.0 0.69 9.0 0.0 2.5 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_28 PF13521.1 KLO05131.1 - 0.0084 16.0 0.0 5.4 6.9 0.0 2.8 2 0 0 2 2 2 0 AAA domain AAA_11 PF13086.1 KLO05131.1 - 0.0085 15.6 0.0 0.2 11.1 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.9 KLO05131.1 - 0.0093 15.6 0.0 4.1 7.1 0.0 3.4 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) Arch_ATPase PF01637.13 KLO05131.1 - 0.0094 15.6 0.0 0.077 12.6 0.0 2.4 2 0 0 2 2 2 1 Archaeal ATPase Mg_chelatase PF01078.16 KLO05131.1 - 0.014 14.6 0.0 5 6.2 0.0 2.7 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI ADK PF00406.17 KLO05131.1 - 0.025 14.4 0.2 7.7 6.3 0.0 2.8 2 0 0 2 2 2 0 Adenylate kinase MMR_HSR1 PF01926.18 KLO05131.1 - 0.031 14.2 0.1 15 5.5 0.0 2.9 2 0 0 2 2 2 0 50S ribosome-binding GTPase Viral_helicase1 PF01443.13 KLO05131.1 - 0.033 13.7 0.0 4.1 6.8 0.0 2.4 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase AAA_29 PF13555.1 KLO05131.1 - 0.034 13.6 0.0 9.6 5.8 0.0 2.5 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_30 PF13604.1 KLO05131.1 - 0.041 13.4 0.1 4 6.9 0.0 2.4 2 0 0 2 2 2 0 AAA domain Miro PF08477.8 KLO05131.1 - 0.044 14.2 0.0 13 6.2 0.0 2.8 2 0 0 2 2 2 0 Miro-like protein Sigma54_activ_2 PF14532.1 KLO05131.1 - 0.053 13.5 0.0 8.2 6.4 0.0 2.7 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_24 PF13479.1 KLO05131.1 - 0.068 12.7 0.3 5.6 6.4 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA_10 PF12846.2 KLO05131.1 - 0.074 12.4 1.8 19 4.5 0.1 3.7 2 1 1 3 3 3 0 AAA-like domain cobW PF02492.14 KLO05131.1 - 0.11 11.9 0.1 4.4 6.7 0.0 2.7 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain ArgK PF03308.11 KLO05131.1 - 0.15 10.7 0.0 10 4.7 0.0 2.4 2 0 0 2 2 2 0 ArgK protein DUF3617 PF12276.3 KLO05132.1 - 0.033 13.6 0.1 0.069 12.6 0.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3617) OrfB_Zn_ribbon PF07282.6 KLO05132.1 - 0.34 10.5 3.4 5.1 6.8 3.1 1.9 2 0 0 2 2 2 0 Putative transposase DNA-binding domain WD40 PF00400.27 KLO05135.1 - 2.3e-72 236.5 30.0 3.4e-13 48.9 0.2 7.7 7 0 0 7 7 7 7 WD domain, G-beta repeat AAA_16 PF13191.1 KLO05135.1 - 1.2e-05 25.4 0.0 2.9e-05 24.1 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain PD40 PF07676.7 KLO05135.1 - 6.2e-05 22.5 1.5 5.1 6.8 0.0 4.9 4 0 0 4 4 4 1 WD40-like Beta Propeller Repeat Nbas_N PF15492.1 KLO05135.1 - 0.00047 19.3 5.9 0.55 9.2 0.0 5.4 2 1 4 6 6 6 1 Neuroblastoma-amplified sequence, N terminal NACHT PF05729.7 KLO05135.1 - 0.00077 19.1 0.1 0.0022 17.6 0.0 1.7 1 1 0 1 1 1 1 NACHT domain AAA_17 PF13207.1 KLO05135.1 - 0.0011 19.7 0.0 0.0028 18.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 KLO05135.1 - 0.0022 17.8 0.0 0.0039 17.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA PF00004.24 KLO05135.1 - 0.0034 17.5 0.0 0.0085 16.2 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Glyoxal_oxid_N PF07250.6 KLO05135.1 - 0.0061 15.6 0.1 2.4 7.1 0.0 2.4 1 1 1 2 2 2 2 Glyoxal oxidase N-terminus Zeta_toxin PF06414.7 KLO05135.1 - 0.0062 15.6 0.0 0.01 14.9 0.0 1.2 1 0 0 1 1 1 1 Zeta toxin Nup160 PF11715.3 KLO05135.1 - 0.0083 14.3 1.1 3.4 5.7 0.1 3.3 1 1 1 3 3 3 1 Nucleoporin Nup120/160 AAA_22 PF13401.1 KLO05135.1 - 0.023 14.8 0.0 0.078 13.1 0.0 1.8 2 0 0 2 2 2 0 AAA domain Nucleoporin_N PF08801.6 KLO05135.1 - 0.028 13.2 0.8 0.87 8.2 0.4 2.9 2 1 0 2 2 2 0 Nup133 N terminal like AAA_18 PF13238.1 KLO05135.1 - 0.063 13.5 0.0 0.13 12.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain Rib_hydrolayse PF02267.12 KLO05135.1 - 0.064 12.5 0.0 0.12 11.7 0.0 1.4 1 0 0 1 1 1 0 ADP-ribosyl cyclase NB-ARC PF00931.17 KLO05135.1 - 0.066 12.0 0.0 0.098 11.4 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain KAP_NTPase PF07693.9 KLO05135.1 - 0.068 12.1 0.4 0.13 11.2 0.0 1.5 2 0 0 2 2 2 0 KAP family P-loop domain Miro PF08477.8 KLO05135.1 - 0.18 12.3 0.0 0.98 9.9 0.0 2.3 2 0 0 2 2 2 0 Miro-like protein SPRY PF00622.23 KLO05137.1 - 3e-26 91.9 0.3 4.9e-26 91.2 0.2 1.4 1 0 0 1 1 1 1 SPRY domain CLTH PF10607.4 KLO05137.1 - 1.3e-23 83.3 0.0 1.8e-23 82.8 0.0 1.2 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain LisH PF08513.6 KLO05137.1 - 1.6e-05 24.4 0.1 5.9e-05 22.6 0.0 2.0 2 0 0 2 2 2 1 LisH ABC_tran PF00005.22 KLO05138.1 - 3e-46 157.1 0.0 1.5e-23 83.5 0.0 2.8 2 0 0 2 2 2 2 ABC transporter ABC_tran_2 PF12848.2 KLO05138.1 - 1.3e-22 79.4 3.8 1.3e-22 79.4 2.6 2.7 2 0 0 2 2 2 1 ABC transporter AAA_21 PF13304.1 KLO05138.1 - 1.3e-15 58.1 7.4 0.001 19.1 0.0 4.6 3 2 0 5 5 4 4 AAA domain AAA_17 PF13207.1 KLO05138.1 - 2.2e-07 31.7 0.1 0.025 15.3 0.0 3.5 3 0 0 3 3 3 2 AAA domain AAA_29 PF13555.1 KLO05138.1 - 3.1e-07 29.8 0.4 0.016 14.6 0.1 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain SMC_N PF02463.14 KLO05138.1 - 4.6e-07 29.3 0.1 0.13 11.4 0.0 4.0 4 0 0 4 4 4 2 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.18 KLO05138.1 - 5.5e-07 29.5 0.0 0.041 13.8 0.0 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase Miro PF08477.8 KLO05138.1 - 2e-06 28.2 0.0 0.052 14.0 0.0 2.7 2 0 0 2 2 2 2 Miro-like protein DUF258 PF03193.11 KLO05138.1 - 3.8e-06 26.1 0.2 0.037 13.2 0.0 2.6 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_22 PF13401.1 KLO05138.1 - 5.4e-06 26.5 2.1 0.038 14.1 0.0 4.0 3 2 0 3 3 3 2 AAA domain AAA_10 PF12846.2 KLO05138.1 - 2.2e-05 24.0 2.1 0.56 9.5 0.1 3.6 4 0 0 4 4 3 2 AAA-like domain AAA_28 PF13521.1 KLO05138.1 - 2.5e-05 24.3 0.1 0.13 12.1 0.0 2.9 2 0 0 2 2 2 2 AAA domain NACHT PF05729.7 KLO05138.1 - 2.7e-05 23.9 0.1 0.26 10.9 0.0 2.8 3 0 0 3 3 2 2 NACHT domain ArgK PF03308.11 KLO05138.1 - 3e-05 22.9 0.3 0.012 14.4 0.0 2.4 2 0 0 2 2 2 2 ArgK protein AAA_16 PF13191.1 KLO05138.1 - 5e-05 23.3 7.5 0.016 15.2 0.3 3.8 4 1 0 4 4 4 2 AAA ATPase domain MobB PF03205.9 KLO05138.1 - 9e-05 22.1 0.4 0.16 11.7 0.0 2.9 3 0 0 3 3 2 2 Molybdopterin guanine dinucleotide synthesis protein B SbcCD_C PF13558.1 KLO05138.1 - 0.0005 19.9 0.1 0.12 12.2 0.0 3.3 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_18 PF13238.1 KLO05138.1 - 0.00073 19.8 4.6 0.96 9.7 0.0 4.2 4 1 1 5 5 5 2 AAA domain AAA_23 PF13476.1 KLO05138.1 - 0.0011 19.3 13.4 0.1 12.8 0.0 4.4 4 1 0 4 4 3 2 AAA domain Dynamin_N PF00350.18 KLO05138.1 - 0.0011 18.8 2.0 0.076 12.8 0.1 3.2 3 0 0 3 3 3 1 Dynamin family AAA_33 PF13671.1 KLO05138.1 - 0.0021 17.9 0.5 0.49 10.2 0.0 3.1 4 0 0 4 4 2 1 AAA domain AAA_14 PF13173.1 KLO05138.1 - 0.0036 17.1 0.2 4.6 7.1 0.0 3.5 4 0 0 4 4 3 0 AAA domain RNA_helicase PF00910.17 KLO05138.1 - 0.0057 16.8 0.0 2.7 8.2 0.0 2.6 2 0 0 2 2 2 1 RNA helicase AAA_25 PF13481.1 KLO05138.1 - 0.0083 15.5 0.0 5.5 6.3 0.0 3.0 2 0 0 2 2 2 0 AAA domain AAA PF00004.24 KLO05138.1 - 0.0095 16.1 0.0 5.4 7.2 0.0 3.1 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) NTPase_1 PF03266.10 KLO05138.1 - 0.019 14.6 0.1 4.6 6.9 0.0 2.7 2 0 0 2 2 2 0 NTPase AAA_30 PF13604.1 KLO05138.1 - 0.019 14.5 0.0 1.6 8.2 0.0 2.6 2 0 0 2 2 2 0 AAA domain DUF815 PF05673.8 KLO05138.1 - 0.021 13.7 0.1 0.87 8.4 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF815) cobW PF02492.14 KLO05138.1 - 0.03 13.7 0.3 6.3 6.2 0.0 2.5 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain DUF87 PF01935.12 KLO05138.1 - 0.038 13.8 0.1 0.038 13.8 0.1 3.5 4 1 0 4 4 3 0 Domain of unknown function DUF87 PduV-EutP PF10662.4 KLO05138.1 - 0.048 13.1 0.1 5 6.6 0.0 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation FeoB_N PF02421.13 KLO05138.1 - 0.061 12.6 0.1 1.3 8.2 0.1 2.5 2 0 0 2 2 2 0 Ferrous iron transport protein B Viral_helicase1 PF01443.13 KLO05138.1 - 0.077 12.4 0.0 16 4.9 0.0 2.5 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase AAA_5 PF07728.9 KLO05138.1 - 0.093 12.4 0.3 5.6 6.6 0.0 3.0 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) AAA_15 PF13175.1 KLO05138.1 - 0.18 10.7 10.8 1.6 7.6 0.1 4.2 4 2 0 5 5 5 0 AAA ATPase domain AAA_13 PF13166.1 KLO05138.1 - 1.6 7.0 10.4 9.9 4.4 0.0 3.7 4 0 0 4 4 4 0 AAA domain Lipase_3 PF01764.20 KLO05140.1 - 8e-15 54.6 0.0 2.2e-14 53.2 0.0 1.7 1 1 0 1 1 1 1 Lipase (class 3) Abhydrolase_5 PF12695.2 KLO05140.1 - 0.021 14.5 0.3 0.067 12.9 0.0 1.9 2 0 0 2 2 2 0 Alpha/beta hydrolase family DUF3328 PF11807.3 KLO05141.1 - 2.1e-12 47.2 0.1 2.2e-12 47.1 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) F-box-like PF12937.2 KLO05141.1 - 0.041 13.6 0.2 0.12 12.1 0.1 1.8 1 1 0 1 1 1 0 F-box-like DUF3265 PF11665.3 KLO05144.1 - 0.059 13.2 0.8 0.13 12.1 0.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3265) DUF1242 PF06842.7 KLO05145.1 - 0.13 11.8 0.0 0.31 10.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1242) TT_ORF2 PF02957.10 KLO05146.1 - 0.1 13.2 0.1 0.1 13.2 0.1 5.3 6 0 0 6 6 6 0 TT viral ORF2 TOH_N PF12549.3 KLO05147.1 - 0.0012 18.2 0.1 0.0056 16.1 0.1 2.3 1 0 0 1 1 1 1 Tyrosine hydroxylase N terminal Apc1 PF12859.2 KLO05147.1 - 0.035 14.3 0.0 0.084 13.1 0.0 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 1 DUF1900 PF08954.6 KLO05151.1 - 2.7e-46 156.4 0.0 5.1e-46 155.5 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1900) DUF1899 PF08953.6 KLO05151.1 - 5.3e-29 99.6 0.0 1.2e-28 98.5 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1899) WD40 PF00400.27 KLO05151.1 - 3.5e-21 74.2 0.2 7.2e-09 35.1 0.0 4.5 5 0 0 5 5 5 3 WD domain, G-beta repeat DUF4140 PF13600.1 KLO05151.1 - 0.0051 17.2 0.1 0.026 14.9 0.4 2.0 2 0 0 2 2 2 1 N-terminal domain of unknown function (DUF4140) Sec2p PF06428.6 KLO05151.1 - 0.01 15.6 1.9 0.021 14.6 1.3 1.4 1 0 0 1 1 1 0 GDP/GTP exchange factor Sec2p CCDC144C PF14915.1 KLO05151.1 - 0.017 14.0 1.3 0.024 13.5 0.9 1.1 1 0 0 1 1 1 0 CCDC144C protein coiled-coil region DivIC PF04977.10 KLO05151.1 - 0.045 13.2 1.8 0.079 12.4 1.3 1.3 1 0 0 1 1 1 0 Septum formation initiator DUF1127 PF06568.6 KLO05152.1 - 3.6 7.0 7.1 5.8 6.4 0.7 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1127) OPT PF03169.10 KLO05160.1 - 1.4e-08 33.6 0.6 1.4e-08 33.6 0.4 1.1 1 0 0 1 1 1 1 OPT oligopeptide transporter protein DUF1918 PF08940.6 KLO05160.1 - 0.15 11.3 0.0 0.24 10.7 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1918) PTRF_SDPR PF15237.1 KLO05162.1 - 0.0098 15.3 0.4 0.02 14.3 0.3 1.5 1 0 0 1 1 1 1 PTRF/SDPR family Mga PF05043.8 KLO05162.1 - 0.023 14.9 0.2 0.053 13.8 0.1 1.5 1 0 0 1 1 1 0 Mga helix-turn-helix domain Fungal_trans PF04082.13 KLO05163.1 - 4.6e-12 45.3 0.1 6.8e-12 44.8 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KLO05163.1 - 5.5e-08 32.6 7.7 9.1e-08 31.8 5.4 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Abdominal-A PF12407.3 KLO05163.1 - 0.0087 15.5 0.0 0.023 14.2 0.0 1.7 1 0 0 1 1 1 1 Homeobox protein Pterin_4a PF01329.14 KLO05163.1 - 0.14 11.9 0.0 0.5 10.1 0.0 1.9 2 0 0 2 2 2 0 Pterin 4 alpha carbinolamine dehydratase Tom22 PF04281.8 KLO05164.1 - 5.6e-40 136.0 1.4 6.6e-40 135.8 1.0 1.1 1 0 0 1 1 1 1 Mitochondrial import receptor subunit Tom22 Glyco_hydro_35 PF01301.14 KLO05165.1 - 7.1e-80 268.7 0.2 1e-79 268.1 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 BetaGal_dom4_5 PF13364.1 KLO05165.1 - 3.3e-46 156.1 7.3 1.4e-23 83.2 0.7 3.5 3 0 0 3 3 3 2 Beta-galactosidase jelly roll domain BetaGal_dom2 PF10435.4 KLO05165.1 - 9.9e-33 113.0 2.3 2.2e-32 111.8 1.6 1.5 1 0 0 1 1 1 1 Beta-galactosidase, domain 2 BetaGal_dom3 PF13363.1 KLO05165.1 - 2.5e-21 74.8 1.7 1.3e-20 72.5 0.2 2.6 3 0 0 3 3 3 1 Beta-galactosidase, domain 3 APH PF01636.18 KLO05167.1 - 0.00024 20.9 0.0 0.00027 20.7 0.0 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family Fructosamin_kin PF03881.9 KLO05167.1 - 0.037 13.0 0.0 0.039 12.9 0.0 1.1 1 0 0 1 1 1 0 Fructosamine kinase APH PF01636.18 KLO05168.1 - 9.9e-05 22.1 0.2 0.00018 21.2 0.0 1.5 2 0 0 2 2 2 1 Phosphotransferase enzyme family adh_short_C2 PF13561.1 KLO05169.1 - 4.4e-17 62.6 0.0 5.1e-17 62.4 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 KLO05169.1 - 1.3e-09 38.1 0.3 1.7e-09 37.7 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase Eno-Rase_NADH_b PF12242.3 KLO05169.1 - 0.011 15.5 0.2 0.026 14.2 0.1 1.7 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase KR PF08659.5 KLO05169.1 - 0.078 12.6 0.0 0.13 11.9 0.0 1.3 1 0 0 1 1 1 0 KR domain Pyr_redox PF00070.22 KLO05169.1 - 0.16 12.3 1.0 0.31 11.4 0.7 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Rota_NSP4 PF01452.11 KLO05170.1 - 0.05 12.9 0.1 0.11 11.7 0.0 1.6 2 0 0 2 2 2 0 Rotavirus non structural protein DUF3092 PF11289.3 KLO05172.1 - 0.029 13.6 0.3 0.03 13.5 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3092) Nop14 PF04147.7 KLO05174.1 - 0.028 12.3 24.4 0.039 11.8 16.9 1.1 1 0 0 1 1 1 0 Nop14-like family RRN3 PF05327.6 KLO05174.1 - 0.14 10.1 4.2 0.18 9.8 2.9 1.3 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Daxx PF03344.10 KLO05174.1 - 0.19 10.1 21.5 0.32 9.4 14.9 1.3 1 0 0 1 1 1 0 Daxx Family CDC45 PF02724.9 KLO05174.1 - 2.1 6.2 14.4 2.7 5.8 10.0 1.1 1 0 0 1 1 1 0 CDC45-like protein SDA1 PF05285.7 KLO05174.1 - 5.3 6.2 21.7 7.4 5.7 15.0 1.2 1 0 0 1 1 1 0 SDA1 Ribosomal_L4 PF00573.17 KLO05177.1 - 1.9e-45 154.6 2.0 1.9e-45 154.6 1.4 1.6 2 0 0 2 2 2 1 Ribosomal protein L4/L1 family Ribos_L4_asso_C PF14374.1 KLO05177.1 - 4.5e-27 93.7 2.4 4.5e-27 93.7 1.7 1.9 2 0 0 2 2 2 1 60S ribosomal protein L4 C-terminal domain DUF1543 PF07566.7 KLO05177.1 - 0.038 13.5 0.4 0.11 12.0 0.0 2.0 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1543) DUF1768 PF08719.6 KLO05178.1 - 1.2e-32 112.8 0.0 1.5e-32 112.5 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1768) DUF4616 PF15394.1 KLO05178.1 - 0.072 12.0 0.2 0.13 11.2 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4616) Fer4_11 PF13247.1 KLO05179.1 - 1.8 8.4 17.4 1.3 8.9 1.2 3.4 2 2 1 3 3 3 0 4Fe-4S dicluster domain PHF5 PF03660.9 KLO05179.1 - 6.8 6.8 10.7 14 5.8 0.5 2.4 2 0 0 2 2 2 0 PHF5-like protein PHF5 PF03660.9 KLO05180.1 - 0.16 12.0 7.7 1.4 9.0 0.1 2.2 2 0 0 2 2 2 0 PHF5-like protein Fer4_11 PF13247.1 KLO05180.1 - 7.4 6.5 13.9 0.36 10.7 0.3 3.0 2 1 1 3 3 3 0 4Fe-4S dicluster domain DUF1768 PF08719.6 KLO05181.1 - 8.8e-31 106.7 0.0 1.1e-30 106.5 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1768) TRAP-gamma PF07074.7 KLO05181.1 - 0.013 15.0 0.0 0.077 12.5 0.0 1.9 2 0 0 2 2 2 0 Translocon-associated protein, gamma subunit (TRAP-gamma) PARP PF00644.15 KLO05182.1 - 3.3e-15 56.0 1.4 1.6e-09 37.5 0.2 3.1 2 1 0 2 2 2 2 Poly(ADP-ribose) polymerase catalytic domain zf-FCS PF06467.9 KLO05182.1 - 0.087 12.4 3.9 1.2 8.8 1.7 2.9 2 0 0 2 2 2 0 MYM-type Zinc finger with FCS sequence motif RPAP2_Rtr1 PF04181.8 KLO05183.1 - 0.12 12.4 0.3 0.12 12.4 0.2 3.4 3 1 0 3 3 3 0 Rtr1/RPAP2 family DUF983 PF06170.7 KLO05185.1 - 0.28 11.3 4.9 0.79 9.8 3.4 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF983) DUF4161 PF13722.1 KLO05185.1 - 0.49 10.7 9.5 0.27 11.5 3.6 2.2 1 1 1 2 2 2 0 C-terminal domain on CstA (DUF4161) ATG22 PF11700.3 KLO05189.1 - 6.8e-107 357.8 17.9 7.8e-107 357.6 12.4 1.0 1 0 0 1 1 1 1 Vacuole effluxer Atg22 like MFS_1 PF07690.11 KLO05189.1 - 6.6e-13 48.0 26.9 5.8e-09 35.1 6.1 3.1 2 1 1 3 3 3 3 Major Facilitator Superfamily SHOCT PF09851.4 KLO05189.1 - 0.0046 16.3 3.4 0.0075 15.7 2.3 1.3 1 0 0 1 1 1 1 Short C-terminal domain GvpG PF05120.7 KLO05189.1 - 0.11 12.2 0.4 0.21 11.4 0.3 1.3 1 0 0 1 1 1 0 Gas vesicle protein G F-box-like PF12937.2 KLO05191.1 - 5.4e-07 29.2 0.7 2.2e-06 27.3 0.0 2.4 2 1 0 2 2 2 1 F-box-like LRR_8 PF13855.1 KLO05191.1 - 0.039 13.6 1.9 10 5.9 0.0 4.1 3 2 0 3 3 3 0 Leucine rich repeat DUF1092 PF06485.6 KLO05191.1 - 0.087 11.7 0.0 0.18 10.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1092) F-box PF00646.28 KLO05191.1 - 0.23 11.1 3.6 17 5.1 0.0 3.6 3 0 0 3 3 3 0 F-box domain LRR_4 PF12799.2 KLO05191.1 - 5.1 6.8 8.1 16 5.2 0.2 3.5 2 2 1 3 3 3 0 Leucine Rich repeats (2 copies) F-box-like PF12937.2 KLO05192.1 - 2e-06 27.4 1.1 6.9e-06 25.6 0.2 2.5 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 KLO05192.1 - 0.032 13.8 2.2 0.71 9.5 1.5 3.2 1 1 0 1 1 1 0 F-box domain F-box-like PF12937.2 KLO05193.1 - 2.9e-08 33.3 0.2 6.2e-08 32.2 0.1 1.6 1 0 0 1 1 1 1 F-box-like F-box-like PF12937.2 KLO05194.1 - 2.4e-08 33.5 0.3 7.3e-08 32.0 0.2 1.9 1 0 0 1 1 1 1 F-box-like Consortin_C PF15281.1 KLO05195.1 - 0.042 13.3 0.1 0.098 12.1 0.1 1.6 1 0 0 1 1 1 0 Consortin C-terminus Reovirus_M2 PF05993.7 KLO05201.1 - 0.095 10.5 0.0 0.12 10.1 0.0 1.1 1 0 0 1 1 1 0 Reovirus major virion structural protein Mu-1/Mu-1C (M2) Streptin-Immun PF11083.3 KLO05203.1 - 0.081 12.9 0.5 0.081 12.9 0.3 1.6 2 0 0 2 2 2 0 Lantibiotic streptin immunity protein Ribosomal_L37e PF01907.14 KLO05204.1 - 0.044 13.5 3.1 0.091 12.5 2.1 1.6 1 1 0 1 1 1 0 Ribosomal protein L37e zf-nanos PF05741.8 KLO05204.1 - 0.095 12.6 0.6 0.15 12.0 0.4 1.5 1 0 0 1 1 1 0 Nanos RNA binding domain LRR_8 PF13855.1 KLO05206.1 - 1.8 8.3 7.3 0.36 10.6 0.1 3.5 3 1 1 4 4 4 0 Leucine rich repeat GMC_oxred_C PF05199.8 KLO05207.1 - 4.1e-13 49.8 0.0 1.1e-12 48.4 0.0 1.8 1 1 0 1 1 1 1 GMC oxidoreductase NAD_Gly3P_dh_N PF01210.18 KLO05207.1 - 0.00078 19.2 0.0 0.0015 18.2 0.0 1.5 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Pyr_redox_2 PF07992.9 KLO05207.1 - 0.0014 18.5 0.1 0.13 12.1 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase F420_oxidored PF03807.12 KLO05207.1 - 0.005 17.2 0.0 0.011 16.1 0.0 1.5 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent 3HCDH_N PF02737.13 KLO05207.1 - 0.028 14.0 0.0 0.048 13.3 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain GMC_oxred_N PF00732.14 KLO05207.1 - 0.028 13.5 0.0 0.091 11.9 0.0 1.7 2 0 0 2 2 2 0 GMC oxidoreductase FAD_binding_3 PF01494.14 KLO05207.1 - 0.039 13.0 0.0 0.065 12.2 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain Thi4 PF01946.12 KLO05207.1 - 0.045 12.8 0.0 0.094 11.7 0.0 1.4 1 0 0 1 1 1 0 Thi4 family NAD_binding_8 PF13450.1 KLO05207.1 - 0.087 12.8 0.0 0.43 10.6 0.0 2.2 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain ELFV_dehydrog PF00208.16 KLO05207.1 - 0.12 11.8 0.0 0.26 10.8 0.0 1.4 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Pyr_redox PF00070.22 KLO05207.1 - 0.13 12.7 0.0 1.5 9.2 0.0 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 KLO05207.1 - 0.15 10.8 0.0 0.26 10.1 0.0 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase GMC_oxred_C PF05199.8 KLO05211.1 - 7e-15 55.5 0.0 1.6e-14 54.3 0.0 1.7 1 1 0 1 1 1 1 GMC oxidoreductase GMC_oxred_N PF00732.14 KLO05211.1 - 0.0081 15.3 0.0 0.013 14.6 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase DUF3173 PF11372.3 KLO05211.1 - 0.1 12.2 0.1 0.79 9.3 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3173) Exo70 PF03081.10 KLO05213.1 - 0.092 11.5 0.0 0.13 11.0 0.0 1.1 1 0 0 1 1 1 0 Exo70 exocyst complex subunit Alpha_kinase PF02816.13 KLO05214.1 - 0.0019 17.8 0.0 0.0019 17.8 0.0 1.2 1 0 0 1 1 1 1 Alpha-kinase family Myco_19_kDa PF05481.7 KLO05214.1 - 0.019 14.7 0.1 0.039 13.7 0.1 1.4 2 0 0 2 2 2 0 Mycobacterium 19 kDa lipoprotein antigen PAP2_3 PF14378.1 KLO05216.1 - 1.2e-11 44.4 11.2 2.1e-11 43.7 7.8 1.3 1 0 0 1 1 1 1 PAP2 superfamily PAP2 PF01569.16 KLO05216.1 - 1.5e-10 40.8 13.6 6.4e-10 38.8 9.4 2.1 1 1 0 1 1 1 1 PAP2 superfamily PAP2_C PF14360.1 KLO05216.1 - 0.00079 19.6 4.1 0.00079 19.6 2.8 2.7 3 1 0 3 3 3 1 PAP2 superfamily C-terminal DnaJ-X PF14308.1 KLO05217.1 - 1.6e-50 171.2 1.1 3e-50 170.3 0.3 1.8 2 0 0 2 2 2 1 X-domain of DnaJ-containing DnaJ PF00226.26 KLO05217.1 - 1.9e-26 91.5 3.0 4.8e-26 90.2 2.0 1.7 1 0 0 1 1 1 1 DnaJ domain PEX11 PF05648.9 KLO05217.1 - 0.32 10.2 1.0 0.43 9.7 0.0 1.7 2 0 0 2 2 2 0 Peroxisomal biogenesis factor 11 (PEX11) LUC7 PF03194.10 KLO05217.1 - 9.7 5.6 9.4 11 5.4 4.0 2.2 1 1 1 2 2 2 0 LUC7 N_terminus Auts2 PF15336.1 KLO05218.1 - 0.045 13.7 0.0 0.06 13.3 0.0 1.2 1 0 0 1 1 1 0 Autism susceptibility gene 2 protein ImmE5 PF11480.3 KLO05218.1 - 0.14 11.9 0.5 0.22 11.3 0.3 1.3 1 0 0 1 1 1 0 Colicin-E5 Imm protein Menin PF05053.8 KLO05219.1 - 0.14 10.3 0.2 0.19 9.8 0.1 1.1 1 0 0 1 1 1 0 Menin Transferrin PF00405.12 KLO05220.1 - 0.0053 15.6 0.3 0.0071 15.2 0.2 1.1 1 0 0 1 1 1 1 Transferrin UBN2_3 PF14244.1 KLO05222.1 - 3.2e-08 33.2 0.1 8.4e-08 31.9 0.1 1.6 1 1 0 1 1 1 1 gag-polypeptide of LTR copia-type UBN2_2 PF14227.1 KLO05222.1 - 9.1e-06 25.2 0.0 1.3e-05 24.6 0.0 1.2 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type DUF4219 PF13961.1 KLO05222.1 - 0.01 15.2 0.1 0.018 14.4 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4219) TFIIA PF03153.8 KLO05228.1 - 2.4e-05 24.4 8.8 2.4e-05 24.4 6.1 2.1 2 1 0 2 2 2 1 Transcription factor IIA, alpha/beta subunit GAS PF13851.1 KLO05228.1 - 0.037 13.2 19.3 0.23 10.6 6.8 2.3 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding SlyX PF04102.7 KLO05228.1 - 1 9.7 15.9 0.54 10.6 0.5 4.7 2 1 1 4 4 4 0 SlyX ADIP PF11559.3 KLO05228.1 - 2.3 8.0 14.2 0.87 9.4 2.7 2.4 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding V_ATPase_I PF01496.14 KLO05228.1 - 3 5.5 8.1 4.8 4.9 5.6 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family NOA36 PF06524.7 KLO05228.1 - 3.4 6.8 9.9 6.8 5.8 6.8 1.4 1 0 0 1 1 1 0 NOA36 protein DUF641 PF04859.7 KLO05228.1 - 8.3 6.1 10.8 7.7 6.2 0.1 3.0 1 1 2 3 3 3 0 Plant protein of unknown function (DUF641) CENP-B_dimeris PF09026.5 KLO05228.1 - 8.9 6.6 17.2 6 7.1 9.9 2.1 2 0 0 2 2 2 0 Centromere protein B dimerisation domain AT_hook PF02178.14 KLO05229.1 - 0.017 14.6 3.3 0.017 14.6 2.3 3.1 2 0 0 2 2 2 0 AT hook motif DDE_3 PF13358.1 KLO05230.1 - 4.3e-10 39.5 0.0 4.3e-10 39.5 0.0 1.0 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_3 PF13358.1 KLO05231.1 - 3.3e-07 30.1 0.0 4.6e-07 29.6 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease DUF4329 PF14220.1 KLO05233.1 - 0.048 13.6 0.0 0.073 13.0 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4329) BTB PF00651.26 KLO05235.1 - 9.7e-07 28.7 0.0 2.9e-06 27.2 0.0 1.7 1 1 0 1 1 1 1 BTB/POZ domain WD40 PF00400.27 KLO05237.1 - 2e-157 506.1 26.7 2.4e-11 43.0 0.0 14.6 14 0 0 14 14 14 14 WD domain, G-beta repeat eIF2A PF08662.6 KLO05237.1 - 2.3e-24 86.1 0.0 0.0004 20.1 0.0 6.3 2 2 4 6 6 6 5 Eukaryotic translation initiation factor eIF2A PD40 PF07676.7 KLO05237.1 - 4.9e-13 48.4 12.5 11 5.8 0.0 12.5 13 0 0 13 13 13 0 WD40-like Beta Propeller Repeat Nup160 PF11715.3 KLO05237.1 - 8.3e-12 44.0 10.7 0.65 8.0 0.0 10.9 3 3 7 10 10 10 3 Nucleoporin Nup120/160 PQQ_2 PF13360.1 KLO05237.1 - 2.2e-09 37.1 12.5 0.00014 21.4 0.2 5.6 1 1 1 3 3 3 2 PQQ-like domain Nbas_N PF15492.1 KLO05237.1 - 2.1e-06 27.0 2.5 1.2 8.1 0.0 6.4 1 1 4 6 6 6 2 Neuroblastoma-amplified sequence, N terminal Arch_ATPase PF01637.13 KLO05237.1 - 6.2e-05 22.8 0.1 0.055 13.1 0.0 3.3 2 1 0 2 2 2 1 Archaeal ATPase PQQ_3 PF13570.1 KLO05237.1 - 9.4e-05 22.5 19.6 4.9 7.5 0.1 9.3 9 2 2 11 11 11 1 PQQ-like domain NACHT PF05729.7 KLO05237.1 - 0.0011 18.6 0.0 0.0035 17.0 0.0 1.8 1 1 0 1 1 1 1 NACHT domain Proteasome_A_N PF10584.4 KLO05237.1 - 0.0041 16.4 12.0 1.5e+02 1.8 0.0 10.3 13 0 0 13 13 13 0 Proteasome subunit A N-terminal signature AAA_16 PF13191.1 KLO05237.1 - 0.0055 16.7 0.1 0.018 15.0 0.1 1.9 1 1 0 1 1 1 1 AAA ATPase domain DsbC_N PF10411.4 KLO05237.1 - 0.0078 15.4 6.9 1.4e+02 1.7 0.0 7.8 8 0 0 8 8 8 0 Disulfide bond isomerase protein N-terminus RNA_helicase PF00910.17 KLO05237.1 - 0.041 14.0 0.0 0.18 11.9 0.0 2.2 1 0 0 1 1 1 0 RNA helicase FANCI_S1-cap PF14674.1 KLO05237.1 - 0.072 13.1 0.0 0.17 11.9 0.0 1.6 1 0 0 1 1 1 0 FANCI solenoid 1 cap AAA_17 PF13207.1 KLO05237.1 - 0.077 13.8 0.8 0.22 12.3 0.1 2.3 2 1 0 2 2 1 0 AAA domain AAA_33 PF13671.1 KLO05237.1 - 0.082 12.7 0.3 0.2 11.5 0.0 1.8 2 0 0 2 2 2 0 AAA domain APS_kinase PF01583.15 KLO05237.1 - 0.15 11.6 0.0 0.34 10.5 0.0 1.6 1 0 0 1 1 1 0 Adenylylsulphate kinase DUF1978 PF09321.5 KLO05239.1 - 0.019 14.4 0.3 0.037 13.4 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1978) DNA_pol_A_exo1 PF01612.15 KLO05240.1 - 0.0017 17.8 0.0 0.0027 17.2 0.0 1.3 1 0 0 1 1 1 1 3'-5' exonuclease zf-Di19 PF05605.7 KLO05241.1 - 0.032 14.3 0.1 0.06 13.4 0.0 1.4 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding BAH PF01426.13 KLO05242.1 - 0.00061 19.5 0.0 0.00098 18.8 0.0 1.3 1 0 0 1 1 1 1 BAH domain PHD PF00628.24 KLO05242.1 - 0.0011 18.5 2.6 0.0011 18.5 1.8 2.0 2 0 0 2 2 2 1 PHD-finger Prok-RING_1 PF14446.1 KLO05242.1 - 0.03 14.0 5.3 0.07 12.8 1.0 2.4 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 DNA_processg_A PF02481.10 KLO05242.1 - 0.08 11.8 0.0 0.12 11.2 0.0 1.2 1 0 0 1 1 1 0 DNA recombination-mediator protein A DUF3104 PF11302.3 KLO05242.1 - 0.091 12.1 0.0 0.19 11.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3104) Phage_integrase PF00589.17 KLO05243.1 - 2.9e-05 23.8 0.1 0.0005 19.7 0.0 2.8 2 1 0 2 2 2 1 Phage integrase family XPG_I PF00867.13 KLO05244.1 - 2.3e-14 53.2 0.0 4.5e-14 52.2 0.0 1.5 1 0 0 1 1 1 1 XPG I-region zf-MYND PF01753.13 KLO05245.1 - 3.7e-08 33.0 15.7 3.7e-08 33.0 10.9 2.2 2 0 0 2 2 2 1 MYND finger BRCT PF00533.21 KLO05246.1 - 3.7e-07 30.1 0.0 6.8e-07 29.3 0.0 1.5 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.2 KLO05246.1 - 5.1e-05 23.0 0.0 0.00012 21.8 0.0 1.7 1 0 0 1 1 1 1 twin BRCT domain fn3 PF00041.16 KLO05246.1 - 0.00075 19.5 0.5 0.0026 17.8 0.4 2.0 1 1 0 1 1 1 1 Fibronectin type III domain DUF3006 PF11213.3 KLO05246.1 - 0.0094 15.6 0.0 0.019 14.6 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3006) Herpes_HEPA PF03324.9 KLO05247.1 - 0.09 12.8 0.0 0.94 9.5 0.0 2.4 3 0 0 3 3 3 0 Herpesvirus DNA helicase/primase complex associated protein DEAD PF00270.24 KLO05248.1 - 1.9e-06 27.4 0.0 2e-06 27.3 0.0 1.1 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.10 KLO05248.1 - 0.023 14.5 0.0 0.023 14.5 0.0 1.1 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_19 PF13245.1 KLO05248.1 - 0.1 12.3 0.0 0.13 12.0 0.0 1.3 1 0 0 1 1 1 0 Part of AAA domain Cauli_VI PF01693.11 KLO05250.1 - 0.0026 17.7 3.2 0.0042 17.0 2.2 1.4 1 0 0 1 1 1 1 Caulimovirus viroplasmin NPV_P10 PF05531.7 KLO05256.1 - 0.017 15.3 1.7 8 6.7 0.1 3.7 4 1 0 4 4 4 0 Nucleopolyhedrovirus P10 protein DUF2422 PF10337.4 KLO05256.1 - 0.024 13.4 0.3 0.048 12.4 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2422) ACCA PF03255.9 KLO05256.1 - 0.064 12.8 0.0 0.3 10.6 0.0 2.2 1 1 0 1 1 1 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit TACC PF05010.9 KLO05256.1 - 0.16 11.7 2.9 0.44 10.2 1.8 2.0 1 1 0 1 1 1 0 Transforming acidic coiled-coil-containing protein (TACC) Sen15 PF09631.5 KLO05258.1 - 3.6e-20 72.0 0.0 4.6e-20 71.7 0.0 1.1 1 0 0 1 1 1 1 Sen15 protein DUF4504 PF14953.1 KLO05260.1 - 0.036 13.3 0.1 0.064 12.5 0.0 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4504) Sen15 PF09631.5 KLO05261.1 - 7.2e-18 64.6 0.0 1e-17 64.2 0.0 1.1 1 0 0 1 1 1 1 Sen15 protein Abi PF02517.11 KLO05262.1 - 8.5 6.5 10.3 20 5.4 7.2 1.7 1 1 0 1 1 1 0 CAAX protease self-immunity DUF1043 PF06295.7 KLO05268.1 - 0.12 12.0 1.6 0.23 11.0 1.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1043) Pecanex_C PF05041.10 KLO05269.1 - 0.076 12.0 0.1 0.095 11.7 0.1 1.1 1 0 0 1 1 1 0 Pecanex protein (C-terminus) RNase_H PF00075.19 KLO05273.1 - 0.00036 20.8 0.0 0.00051 20.3 0.0 1.2 1 0 0 1 1 1 1 RNase H RCR PF12273.3 KLO05276.1 - 0.026 15.0 0.0 0.05 14.1 0.0 1.4 1 0 0 1 1 1 0 Chitin synthesis regulation, resistance to Congo red DUF493 PF04359.9 KLO05278.1 - 0.062 13.6 0.1 0.21 11.9 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF493) SOG2 PF10428.4 KLO05282.1 - 7.9 5.0 9.4 12 4.3 6.5 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein PS_Dcarbxylase PF02666.10 KLO05283.1 - 2.2e-29 102.2 0.0 3.1e-29 101.7 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase PSDC PF12588.3 KLO05283.1 - 2.8e-29 101.5 0.0 4.4e-29 100.9 0.0 1.3 1 0 0 1 1 1 1 Phophatidylserine decarboxylase Biotin_lipoyl_2 PF13533.1 KLO05283.1 - 0.15 11.7 0.4 9.8 5.9 0.0 2.4 2 0 0 2 2 2 0 Biotin-lipoyl like Peptidase_M20 PF01546.23 KLO05284.1 - 2.2e-26 92.5 0.0 3e-26 92.1 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 KLO05284.1 - 4.2e-09 36.1 0.0 6.9e-09 35.4 0.0 1.3 1 0 0 1 1 1 1 Peptidase dimerisation domain Methuselah_N PF06652.7 KLO05284.1 - 0.033 13.7 0.0 0.068 12.7 0.0 1.4 1 0 0 1 1 1 0 Methuselah N-terminus WD40 PF00400.27 KLO05285.1 - 1.8e-20 72.0 26.4 7.8e-08 31.9 1.6 6.8 7 0 0 7 7 7 6 WD domain, G-beta repeat Arginase PF00491.16 KLO05286.1 - 3.1e-85 285.8 0.2 3.9e-85 285.5 0.2 1.0 1 0 0 1 1 1 1 Arginase family RicinB_lectin_2 PF14200.1 KLO05287.1 - 7.3e-06 26.2 0.0 1.7e-05 25.1 0.0 1.6 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain-like Ricin_B_lectin PF00652.17 KLO05287.1 - 0.0014 18.6 0.0 0.0025 17.8 0.0 1.4 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain Pkinase PF00069.20 KLO05288.1 - 2.1e-05 23.8 0.6 0.002 17.3 0.2 2.9 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 KLO05288.1 - 0.0054 15.8 0.3 0.023 13.7 0.3 2.0 2 1 0 2 2 2 1 Protein tyrosine kinase Kdo PF06293.9 KLO05288.1 - 0.011 14.7 1.3 1.2 8.1 0.1 3.1 2 1 1 3 3 3 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KLO05288.1 - 0.094 12.4 0.0 0.26 11.0 0.0 1.8 1 0 0 1 1 1 0 Phosphotransferase enzyme family UBN2 PF14223.1 KLO05289.1 - 0.0017 18.1 0.1 0.0021 17.8 0.1 1.2 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type DUF4218 PF13960.1 KLO05295.1 - 6.8e-06 25.5 0.2 1.3e-05 24.6 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4218) Transposase_21 PF02992.9 KLO05295.1 - 0.00018 20.6 0.0 0.0003 19.9 0.0 1.4 1 0 0 1 1 1 1 Transposase family tnp2 Spt5-NGN PF03439.8 KLO05297.1 - 5.8e-06 25.9 0.0 1e-05 25.2 0.0 1.4 1 0 0 1 1 1 1 Early transcription elongation factor of RNA pol II, NGN section Afi1 PF07792.7 KLO05298.1 - 0.023 14.7 1.4 0.033 14.2 1.0 1.2 1 0 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking EnY2 PF10163.4 KLO05298.1 - 0.05 13.5 0.0 0.08 12.8 0.0 1.3 1 0 0 1 1 1 0 Transcription factor e(y)2 NusB PF01029.13 KLO05304.1 - 0.046 13.6 0.1 0.053 13.5 0.0 1.1 1 0 0 1 1 1 0 NusB family WD40 PF00400.27 KLO05305.1 - 1.9e-10 40.2 15.9 2e-06 27.4 0.0 5.6 6 1 0 6 6 6 4 WD domain, G-beta repeat DNA_pol_B PF00136.16 KLO05308.1 - 3.2e-144 481.1 3.1 1.3e-143 479.1 1.5 2.0 2 0 0 2 2 2 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.14 KLO05308.1 - 3.2e-84 282.5 0.1 8.3e-84 281.2 0.0 1.8 2 0 0 2 2 2 1 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.1 KLO05308.1 - 1.7e-21 76.0 7.1 1.7e-21 76.0 4.9 1.8 2 0 0 2 2 2 1 C4-type zinc-finger of DNA polymerase delta DNA_pol_B_2 PF03175.8 KLO05308.1 - 0.00079 18.2 0.6 0.0089 14.7 0.0 2.2 2 0 0 2 2 2 1 DNA polymerase type B, organellar and viral DNA_pol_B_exo2 PF10108.4 KLO05308.1 - 0.0015 18.0 0.0 0.0033 16.9 0.0 1.6 1 0 0 1 1 1 1 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB RNase_H_2 PF13482.1 KLO05308.1 - 0.02 14.7 0.0 0.069 12.9 0.0 2.0 1 1 0 1 1 1 0 RNase_H superfamily Ribosomal_L34 PF00468.12 KLO05310.1 - 7.9e-16 57.4 11.3 1.2e-15 56.9 7.9 1.3 1 0 0 1 1 1 1 Ribosomal protein L34 DEP PF00610.16 KLO05311.1 - 4.2e-12 45.6 0.0 6.6e-12 44.9 0.0 1.3 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) DNA_pol_B_thumb PF14791.1 KLO05311.1 - 0.11 12.1 0.0 0.21 11.2 0.0 1.4 1 0 0 1 1 1 0 DNA polymerase beta thumb Ribosomal_L7Ae PF01248.21 KLO05312.1 - 1.2e-21 75.9 0.0 1.5e-21 75.6 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family F-box-like PF12937.2 KLO05313.1 - 0.0028 17.3 0.2 0.019 14.6 0.2 2.5 1 0 0 1 1 1 1 F-box-like Methyltransf_23 PF13489.1 KLO05315.1 - 1.9e-11 43.9 0.0 2.9e-11 43.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KLO05315.1 - 2.8e-07 30.9 0.0 5.9e-07 29.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KLO05315.1 - 0.00051 19.6 0.0 0.00075 19.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.10 KLO05315.1 - 0.0011 18.6 0.0 0.0017 18.0 0.0 1.2 1 0 0 1 1 1 1 Hypothetical methyltransferase Methyltransf_29 PF03141.11 KLO05315.1 - 0.0026 16.1 0.0 0.0048 15.3 0.0 1.4 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_12 PF08242.7 KLO05315.1 - 0.0037 17.7 0.0 0.0064 16.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KLO05315.1 - 0.013 16.0 0.2 2 9.0 0.0 2.5 1 1 1 2 2 2 0 Methyltransferase domain Ubie_methyltran PF01209.13 KLO05315.1 - 0.014 14.5 0.0 0.033 13.2 0.0 1.6 2 0 0 2 2 2 0 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.1 KLO05315.1 - 0.042 14.2 0.0 0.076 13.3 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain GIDE PF12483.3 KLO05316.1 - 0.028 13.7 0.0 0.46 9.8 0.0 2.2 2 0 0 2 2 2 0 E3 Ubiquitin ligase zf-MYND PF01753.13 KLO05318.1 - 2.1e-07 30.6 6.4 2.1e-07 30.6 4.4 2.6 2 0 0 2 2 2 1 MYND finger KOW PF00467.24 KLO05325.1 - 1.1e-08 34.4 10.8 0.0054 16.3 0.5 4.7 5 0 0 5 5 5 3 KOW motif Spt5-NGN PF03439.8 KLO05325.1 - 6.5e-08 32.2 0.0 1.7e-07 30.8 0.0 1.8 1 0 0 1 1 1 1 Early transcription elongation factor of RNA pol II, NGN section DUF1793 PF08760.6 KLO05329.1 - 8.4e-23 81.0 0.0 1.5e-22 80.2 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1793) Glyco_hydro_52 PF03512.8 KLO05329.1 - 0.0083 14.7 0.0 0.013 14.0 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 52 GBA2_N PF12215.3 KLO05329.1 - 0.01 15.0 0.1 0.022 13.9 0.1 1.4 1 0 0 1 1 1 0 beta-Glucocerebrosidase 2 N terminal Bac_rhamnosid PF05592.6 KLO05329.1 - 0.028 12.6 0.4 0.064 11.4 0.0 1.7 2 0 0 2 2 2 0 Bacterial alpha-L-rhamnosidase APH PF01636.18 KLO05332.1 - 0.0036 17.0 0.5 0.068 12.9 0.2 2.1 2 0 0 2 2 2 1 Phosphotransferase enzyme family HTH_Tnp_Mu_1 PF02316.11 KLO05332.1 - 0.0063 16.2 0.0 0.01 15.5 0.0 1.3 1 0 0 1 1 1 1 Mu DNA-binding domain Aldo_ket_red PF00248.16 KLO05337.1 - 1.5e-62 211.0 0.0 1.7e-62 210.8 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family F-box-like PF12937.2 KLO05338.1 - 1.1e-06 28.2 0.1 5e-06 26.1 0.0 2.2 1 0 0 1 1 1 1 F-box-like zinc_ribbon_2 PF13240.1 KLO05344.1 - 0.29 10.6 2.1 0.87 9.1 0.2 2.3 2 0 0 2 2 2 0 zinc-ribbon domain G10 PF01125.12 KLO05345.1 - 1.5e-62 209.4 7.1 1.7e-62 209.2 4.9 1.0 1 0 0 1 1 1 1 G10 protein DNA_RNApol_7kD PF03604.8 KLO05345.1 - 0.035 13.5 4.9 0.035 13.5 3.4 2.0 2 0 0 2 2 2 0 DNA directed RNA polymerase, 7 kDa subunit Velvet PF11754.3 KLO05346.1 - 7.8e-52 175.8 0.0 2e-50 171.2 0.0 2.2 1 1 0 1 1 1 1 Velvet factor PPR_2 PF13041.1 KLO05347.1 - 4.1e-37 125.9 0.1 5.9e-11 42.1 0.1 10.3 6 2 5 11 11 11 7 PPR repeat family PPR_3 PF13812.1 KLO05347.1 - 5.2e-35 116.7 9.7 0.00032 20.7 0.0 14.1 15 0 0 15 15 15 7 Pentatricopeptide repeat domain PPR PF01535.15 KLO05347.1 - 6.2e-29 97.9 7.9 0.0061 16.4 0.1 12.3 13 0 0 13 13 13 8 PPR repeat PPR_1 PF12854.2 KLO05347.1 - 2.7e-18 65.1 0.0 6.7e-06 25.4 0.0 6.7 6 0 0 6 6 6 4 PPR repeat TPR_14 PF13428.1 KLO05347.1 - 3.4e-08 33.4 7.8 11 6.9 0.1 8.4 6 2 2 8 8 8 1 Tetratricopeptide repeat BTAD PF03704.12 KLO05347.1 - 0.0021 18.3 3.7 0.94 9.7 0.2 4.0 3 0 0 3 3 3 2 Bacterial transcriptional activator domain TPR_6 PF13174.1 KLO05347.1 - 0.0092 16.3 4.6 41 4.9 0.1 5.3 4 0 0 4 4 4 0 Tetratricopeptide repeat RPM2 PF08579.6 KLO05347.1 - 0.13 12.4 0.0 68 3.6 0.0 3.7 4 0 0 4 4 4 0 Mitochondrial ribonuclease P subunit (RPM2) SBDS PF01172.13 KLO05348.1 - 2.4e-06 27.2 0.0 4.7e-06 26.3 0.0 1.5 1 1 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein OrfB_Zn_ribbon PF07282.6 KLO05350.1 - 0.042 13.4 1.9 0.09 12.4 1.3 1.5 1 0 0 1 1 1 0 Putative transposase DNA-binding domain Ribosomal_L7Ae PF01248.21 KLO05353.1 - 4.7e-27 93.3 2.2 6e-27 93.0 1.5 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family DUF1269 PF06897.7 KLO05353.1 - 0.017 15.0 0.1 0.031 14.3 0.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1269) SpoU_sub_bind PF08032.7 KLO05353.1 - 0.065 13.3 0.3 2.3 8.4 0.0 2.2 1 1 1 2 2 2 0 RNA 2'-O ribose methyltransferase substrate binding AF0941-like PF14591.1 KLO05353.1 - 0.069 13.1 0.1 0.11 12.6 0.1 1.4 1 1 0 1 1 1 0 AF0941-like FliM PF02154.10 KLO05353.1 - 0.16 11.6 0.0 0.21 11.2 0.0 1.1 1 0 0 1 1 1 0 Flagellar motor switch protein FliM Arb1 PF09692.5 KLO05354.1 - 4.3e-07 29.1 0.2 8.2e-07 28.1 0.2 1.5 1 0 0 1 1 1 1 Argonaute siRNA chaperone (ARC) complex subunit Arb1 gag_pre-integrs PF13976.1 KLO05358.1 - 0.00025 20.6 0.0 0.00035 20.1 0.0 1.3 1 0 0 1 1 1 1 GAG-pre-integrase domain Spt5-NGN PF03439.8 KLO05360.1 - 1.5e-13 50.2 0.0 3.6e-13 49.0 0.0 1.7 1 0 0 1 1 1 1 Early transcription elongation factor of RNA pol II, NGN section DHC PF09626.5 KLO05360.1 - 0.00028 21.5 0.0 0.0072 16.9 0.0 2.5 2 0 0 2 2 2 1 Dihaem cytochrome c KOW PF00467.24 KLO05360.1 - 0.01 15.5 0.5 0.01 15.5 0.3 4.3 4 0 0 4 4 4 2 KOW motif BsuPI PF12690.2 KLO05360.1 - 0.16 11.6 1.1 0.33 10.7 0.1 2.0 2 0 0 2 2 2 0 Intracellular proteinase inhibitor Fe-S_biosyn PF01521.15 KLO05365.1 - 5e-06 26.4 0.0 6.7e-06 26.0 0.0 1.2 1 0 0 1 1 1 1 Iron-sulphur cluster biosynthesis DUF814 PF05670.8 KLO05366.1 - 1e-23 83.0 0.8 3.3e-23 81.3 0.0 2.1 2 1 0 2 2 2 1 Domain of unknown function (DUF814) RsgI_N PF12791.2 KLO05366.1 - 0.15 11.7 1.1 0.5 10.0 0.2 2.3 2 1 0 2 2 2 0 Anti-sigma factor N-terminus Phosducin PF02114.11 KLO05366.1 - 3.6 6.2 9.1 4.9 5.8 6.3 1.2 1 0 0 1 1 1 0 Phosducin Pkinase PF00069.20 KLO05367.1 - 4.4e-17 62.0 0.0 6.1e-17 61.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KLO05367.1 - 2.3e-14 53.1 0.0 2.8e-14 52.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pox_MCEL PF03291.11 KLO05368.1 - 1.1e-61 208.5 0.0 3.2e-61 207.0 0.0 1.6 1 1 0 1 1 1 1 mRNA capping enzyme Pkinase PF00069.20 KLO05368.1 - 1.4e-09 37.5 0.0 2.3e-09 36.7 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Methyltransf_31 PF13847.1 KLO05368.1 - 2.9e-08 33.4 0.0 5.1e-08 32.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KLO05368.1 - 3e-08 34.0 0.0 6.6e-08 32.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KLO05368.1 - 3.2e-08 34.1 0.0 7.9e-08 32.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KLO05368.1 - 1.3e-06 28.2 0.0 2.5e-06 27.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Pkinase_Tyr PF07714.12 KLO05368.1 - 6.3e-06 25.4 0.0 9.7e-06 24.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Methyltransf_25 PF13649.1 KLO05368.1 - 6.9e-06 26.3 0.0 1.2e-05 25.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KLO05368.1 - 0.00014 22.2 0.0 0.0012 19.2 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain NNMT_PNMT_TEMT PF01234.12 KLO05368.1 - 0.11 11.4 0.0 0.2 10.5 0.0 1.4 1 0 0 1 1 1 0 NNMT/PNMT/TEMT family DUF3021 PF11457.3 KLO05372.1 - 0.32 10.8 7.2 0.29 11.0 3.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3021) TMEM169 PF15052.1 KLO05372.1 - 1.3 8.8 6.3 20 5.1 1.8 2.6 2 1 0 3 3 3 0 TMEM169 protein family Glyco_hydro_15 PF00723.16 KLO05374.1 - 5.3e-93 312.0 0.0 6.3e-93 311.7 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 15 CBM_20 PF00686.14 KLO05374.1 - 1.7e-28 98.0 0.4 4.1e-28 96.8 0.3 1.7 1 0 0 1 1 1 1 Starch binding domain Methyltransf_33 PF10017.4 KLO05375.1 - 2.3e-31 108.3 0.1 4.5e-31 107.3 0.1 1.5 1 0 0 1 1 1 1 Histidine-specific methyltransferase, SAM-dependent FGE-sulfatase PF03781.11 KLO05375.1 - 1.9e-22 79.9 0.2 5.5e-14 52.1 0.0 2.3 2 0 0 2 2 2 2 Sulfatase-modifying factor enzyme 1 DinB_2 PF12867.2 KLO05375.1 - 5.5e-06 26.7 1.3 1.4e-05 25.4 0.9 1.7 1 0 0 1 1 1 1 DinB superfamily GPI-anchored PF10342.4 KLO05377.1 - 1.2e-07 32.1 1.1 1.5e-07 31.7 0.8 1.1 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Sugar_tr PF00083.19 KLO05379.1 - 4.7e-37 127.6 16.5 1.8e-21 76.2 1.0 2.0 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 KLO05379.1 - 7.8e-20 70.8 34.6 3.6e-13 48.9 9.7 2.1 1 1 0 2 2 2 2 Major Facilitator Superfamily IPK PF03770.11 KLO05380.1 - 0.087 12.4 0.1 0.087 12.4 0.0 1.2 1 0 0 1 1 1 0 Inositol polyphosphate kinase F-box-like PF12937.2 KLO05382.1 - 0.0019 17.8 2.7 0.006 16.2 1.8 1.9 1 1 0 1 1 1 1 F-box-like F-box PF00646.28 KLO05382.1 - 0.36 10.5 3.9 0.46 10.2 1.0 2.6 2 0 0 2 2 2 0 F-box domain F-box-like PF12937.2 KLO05383.1 - 1.9e-06 27.4 1.7 6.7e-06 25.7 1.2 2.1 1 0 0 1 1 1 1 F-box-like F-box-like PF12937.2 KLO05384.1 - 0.005 16.5 3.5 0.005 16.5 2.4 2.7 2 1 0 2 2 2 1 F-box-like F-box-like PF12937.2 KLO05385.1 - 9.3e-07 28.4 1.7 9.3e-07 28.4 1.2 2.8 2 0 0 2 2 2 1 F-box-like Mak16 PF04874.9 KLO05385.1 - 0.26 11.3 0.0 1.1 9.4 0.0 1.9 2 0 0 2 2 2 0 Mak16 protein C-terminal region Methyltransf_5 PF01795.14 KLO05387.1 - 0.0037 16.5 0.0 0.0064 15.8 0.0 1.3 1 0 0 1 1 1 1 MraW methylase family DUF3702 PF12486.3 KLO05387.1 - 0.095 12.3 0.2 0.21 11.2 0.0 1.6 2 0 0 2 2 2 0 ImpA domain protein Mei4 PF13971.1 KLO05389.1 - 0.0044 16.0 0.3 0.0044 16.0 0.2 2.0 2 1 1 3 3 3 1 Meiosis-specific protein Mei4 Y_phosphatase PF00102.22 KLO05390.1 - 1.7e-58 197.7 0.0 3.4e-32 111.6 0.0 3.2 3 0 0 3 3 3 3 Protein-tyrosine phosphatase Rhodanese PF00581.15 KLO05390.1 - 5.9e-08 33.0 0.0 1.4e-07 31.8 0.0 1.7 1 0 0 1 1 1 1 Rhodanese-like domain Y_phosphatase3 PF13350.1 KLO05390.1 - 0.048 13.9 0.0 0.12 12.5 0.0 1.7 1 0 0 1 1 1 0 Tyrosine phosphatase family PTPlike_phytase PF14566.1 KLO05390.1 - 0.084 12.9 0.0 0.51 10.3 0.0 2.1 2 0 0 2 2 2 0 Inositol hexakisphosphate KIAA1328 PF15369.1 KLO05390.1 - 0.84 9.3 4.6 1.9 8.1 3.2 1.5 1 0 0 1 1 1 0 Uncharacterised protein KIAA1328 SNF2_N PF00176.18 KLO05391.1 - 5.7e-83 278.1 0.9 1e-82 277.2 0.6 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain Bromodomain PF00439.20 KLO05391.1 - 1.4e-18 66.5 0.1 4.4e-18 64.9 0.1 1.9 1 0 0 1 1 1 1 Bromodomain Helicase_C PF00271.26 KLO05391.1 - 2.4e-18 65.7 0.1 2.6e-16 59.2 0.0 3.3 3 0 0 3 3 3 1 Helicase conserved C-terminal domain HSA PF07529.8 KLO05391.1 - 3.8e-15 55.4 7.5 3.8e-15 55.4 5.2 2.4 2 0 0 2 2 2 1 HSA SnAC PF14619.1 KLO05391.1 - 2e-11 43.9 0.0 2e-11 43.9 0.0 4.0 2 1 1 3 3 3 1 Snf2-ATP coupling, chromatin remodelling complex QLQ PF08880.6 KLO05391.1 - 1.9e-07 30.3 0.0 5.6e-07 28.8 0.0 1.8 1 0 0 1 1 1 1 QLQ Ku PF02735.11 KLO05392.1 - 2.5e-29 102.1 0.0 7.8e-29 100.5 0.0 1.8 1 0 0 1 1 1 1 Ku70/Ku80 beta-barrel domain Ku_N PF03731.10 KLO05392.1 - 3.8e-14 52.6 0.0 1e-13 51.2 0.0 1.7 1 0 0 1 1 1 1 Ku70/Ku80 N-terminal alpha/beta domain Ku_PK_bind PF08785.6 KLO05392.1 - 8.2e-13 48.3 0.0 1.5e-12 47.4 0.0 1.5 1 0 0 1 1 1 1 Ku C terminal domain like VWA_2 PF13519.1 KLO05392.1 - 2e-05 24.7 0.0 3.7e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.23 KLO05392.1 - 0.00019 21.2 0.0 0.00039 20.1 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain DUF4330 PF14221.1 KLO05392.1 - 0.018 14.9 0.1 0.041 13.7 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4330) DUF4045 PF13254.1 KLO05392.1 - 0.88 8.7 16.0 0.031 13.5 3.9 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4045) CHAT PF12770.2 KLO05393.1 - 5.9e-31 107.6 0.0 7.4e-31 107.3 0.0 1.2 1 0 0 1 1 1 1 CHAT domain Acetyltransf_1 PF00583.19 KLO05394.1 - 5.5e-05 23.1 0.0 6.4e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family GNAT_acetyltr_2 PF13718.1 KLO05394.1 - 0.021 14.1 0.0 0.023 13.9 0.0 1.2 1 0 0 1 1 1 0 GNAT acetyltransferase 2 Acetyltransf_10 PF13673.1 KLO05394.1 - 0.039 14.0 0.0 0.056 13.5 0.0 1.5 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 KLO05394.1 - 0.11 12.7 0.0 0.14 12.3 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 KLO05395.1 - 1.3e-08 34.7 0.0 2.3e-08 33.9 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 KLO05395.1 - 3.5e-06 27.0 0.0 1.6e-05 24.9 0.0 2.0 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 KLO05395.1 - 9e-06 25.8 0.0 4.5e-05 23.5 0.0 2.0 1 1 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 KLO05395.1 - 3.3e-05 23.5 0.0 6e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_CG PF14542.1 KLO05395.1 - 0.015 15.1 0.0 0.034 14.0 0.0 1.5 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Acetyltransf_9 PF13527.1 KLO05395.1 - 0.043 13.6 0.0 1.1 9.1 0.0 2.5 2 1 0 2 2 2 0 Acetyltransferase (GNAT) domain Pkinase PF00069.20 KLO05396.1 - 7e-40 136.8 0.0 9.1e-40 136.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KLO05396.1 - 1.7e-34 119.0 0.0 2.2e-34 118.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KLO05396.1 - 0.00014 20.9 0.0 0.00022 20.3 0.0 1.2 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.17 KLO05396.1 - 0.074 12.3 0.0 0.24 10.7 0.0 1.8 2 0 0 2 2 2 0 RIO1 family p450 PF00067.17 KLO05397.1 - 1.5e-59 201.7 0.0 2.2e-59 201.2 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 Acetyltransf_7 PF13508.1 KLO05398.1 - 2e-08 34.2 0.1 8.7e-08 32.2 0.0 1.9 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 KLO05398.1 - 1.9e-07 31.0 0.0 4.7e-07 29.7 0.0 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 KLO05398.1 - 3.1e-06 27.2 0.0 5.1e-05 23.3 0.0 2.2 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 KLO05398.1 - 8.9e-05 22.1 0.0 0.00016 21.3 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein MOZ_SAS PF01853.13 KLO05398.1 - 0.16 11.1 0.0 0.26 10.5 0.0 1.3 1 0 0 1 1 1 0 MOZ/SAS family DrrA_P4M PF14860.1 KLO05399.1 - 0.097 12.4 0.0 0.12 12.1 0.0 1.1 1 0 0 1 1 1 0 DrrA phosphatidylinositol 4-phosphate binding domain F-box-like PF12937.2 KLO05401.1 - 4.9e-05 22.9 0.4 0.00019 21.0 0.2 2.1 1 1 0 1 1 1 1 F-box-like Acetyltransf_1 PF00583.19 KLO05402.1 - 4.6e-07 29.7 0.0 6.4e-07 29.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 KLO05402.1 - 1.3e-06 28.4 0.0 1.8e-06 27.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 KLO05402.1 - 7.3e-05 22.8 0.0 0.0001 22.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain DUF3749 PF12568.3 KLO05402.1 - 0.0061 16.1 0.0 0.016 14.7 0.0 1.6 1 1 1 2 2 2 1 Acetyltransferase (GNAT) domain MOZ_SAS PF01853.13 KLO05402.1 - 0.052 12.7 0.0 0.057 12.6 0.0 1.2 1 0 0 1 1 1 0 MOZ/SAS family BTB PF00651.26 KLO05403.1 - 3.6e-08 33.3 0.0 9.9e-08 31.9 0.0 1.7 1 0 0 1 1 1 1 BTB/POZ domain BTB PF00651.26 KLO05404.1 - 8.3e-07 28.9 0.0 2e-06 27.7 0.0 1.6 1 0 0 1 1 1 1 BTB/POZ domain DEAD PF00270.24 KLO05405.1 - 5e-12 45.6 0.1 1.2e-11 44.4 0.1 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KLO05405.1 - 5.6e-09 35.7 0.0 2.2e-08 33.8 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain RasGAP_C PF03836.10 KLO05405.1 - 0.01 15.5 0.6 0.023 14.3 0.4 1.5 1 0 0 1 1 1 0 RasGAP C-terminus ResIII PF04851.10 KLO05405.1 - 0.018 14.8 0.0 0.018 14.8 0.0 2.5 3 0 0 3 3 3 0 Type III restriction enzyme, res subunit DUF515 PF04415.7 KLO05405.1 - 1.1 7.4 8.8 2 6.5 6.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF515) BTB PF00651.26 KLO05407.1 - 4.8e-05 23.3 0.0 8.9e-05 22.4 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain BTB PF00651.26 KLO05408.1 - 3.6e-05 23.7 0.0 6.8e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain DUF4428 PF14471.1 KLO05408.1 - 0.017 14.8 0.0 0.039 13.6 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4428) BTB PF00651.26 KLO05409.1 - 2.4e-07 30.7 0.0 3.3e-07 30.2 0.0 1.1 1 0 0 1 1 1 1 BTB/POZ domain BTB PF00651.26 KLO05410.1 - 4.8e-06 26.5 0.0 9.9e-06 25.5 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain TRF PF08558.5 KLO05411.1 - 0.068 12.5 0.2 0.095 12.0 0.2 1.2 1 0 0 1 1 1 0 Telomere repeat binding factor (TRF) Tox-WTIP PF15654.1 KLO05413.1 - 0.047 13.3 0.7 0.25 10.9 0.4 2.1 2 0 0 2 2 2 0 Toxin with a conserved tryptophan and TIP tripeptide motif SWIM PF04434.12 KLO05416.1 - 0.11 11.9 0.0 0.21 11.0 0.0 1.4 1 0 0 1 1 1 0 SWIM zinc finger Methyltransf_2 PF00891.13 KLO05417.1 - 3.7e-24 85.2 0.0 2.2e-23 82.7 0.0 1.9 1 1 0 1 1 1 1 O-methyltransferase p450 PF00067.17 KLO05418.1 - 5.7e-65 219.6 0.0 1e-64 218.7 0.0 1.4 1 1 0 1 1 1 1 Cytochrome P450 HNH_2 PF13391.1 KLO05419.1 - 4.8e-09 35.8 0.2 1.2e-08 34.5 0.1 1.7 1 0 0 1 1 1 1 HNH endonuclease Transposase_21 PF02992.9 KLO05421.1 - 5.3e-07 28.9 0.0 9.3e-07 28.1 0.0 1.3 1 0 0 1 1 1 1 Transposase family tnp2 ChW PF07538.6 KLO05421.1 - 0.098 12.1 0.0 0.25 10.9 0.0 1.6 1 0 0 1 1 1 0 Clostridial hydrophobic W Spt5-NGN PF03439.8 KLO05423.1 - 3.9e-09 36.1 0.1 9.5e-09 34.8 0.1 1.7 1 0 0 1 1 1 1 Early transcription elongation factor of RNA pol II, NGN section KOW PF00467.24 KLO05423.1 - 1.3e-07 31.0 21.1 0.077 12.7 0.2 6.2 6 0 0 6 6 6 5 KOW motif YueH PF14166.1 KLO05424.1 - 0.11 12.2 0.6 4.1 7.2 0.1 2.3 2 0 0 2 2 2 0 YueH-like protein Pox_VERT_large PF04441.8 KLO05424.1 - 0.12 10.4 0.0 0.15 10.1 0.0 1.1 1 0 0 1 1 1 0 Poxvirus early transcription factor (VETF), large subunit Nop14 PF04147.7 KLO05425.1 - 0.12 10.2 0.2 0.17 9.8 0.2 1.2 1 0 0 1 1 1 0 Nop14-like family Na_trans_assoc PF06512.8 KLO05425.1 - 0.27 11.1 1.4 2.1 8.2 0.9 2.2 2 0 0 2 2 2 0 Sodium ion transport-associated DUF3525 PF12039.3 KLO05426.1 - 0.077 11.4 0.8 0.13 10.7 0.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3525) His_Phos_2 PF00328.17 KLO05428.1 - 3.9e-05 23.1 0.3 0.00068 19.0 0.2 2.5 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) DUF812 PF05667.6 KLO05430.1 - 0.00031 19.4 4.8 0.00048 18.7 3.4 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF812) DUF724 PF05266.9 KLO05430.1 - 0.009 15.6 3.6 0.032 13.8 2.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF724) DUF3829 PF12889.2 KLO05430.1 - 0.022 13.9 4.7 0.036 13.2 1.9 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3829) DASH_Duo1 PF08651.5 KLO05430.1 - 0.048 13.2 0.3 0.33 10.5 0.1 2.3 2 0 0 2 2 2 0 DASH complex subunit Duo1 Baculo_PEP_C PF04513.7 KLO05430.1 - 0.076 12.8 1.0 0.17 11.7 0.7 1.6 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Atg14 PF10186.4 KLO05430.1 - 0.087 11.7 6.9 0.037 12.9 3.2 1.5 2 0 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 Syntaxin PF00804.20 KLO05430.1 - 0.41 10.8 7.4 1.1 9.4 1.1 2.7 1 1 1 2 2 2 0 Syntaxin DUF4407 PF14362.1 KLO05430.1 - 5.1 5.9 8.6 8.2 5.2 5.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) HSP70 PF00012.15 KLO05431.1 - 0.00014 19.9 0.1 0.00056 17.9 0.1 1.8 1 1 0 1 1 1 1 Hsp70 protein NDUF_B6 PF09782.4 KLO05431.1 - 0.068 13.0 0.1 0.13 12.1 0.1 1.4 1 0 0 1 1 1 0 NADH:ubiquinone oxidoreductase, NDUFB6/B17 subunit FAM47 PF14642.1 KLO05431.1 - 0.14 11.4 0.0 0.96 8.6 0.0 2.0 2 0 0 2 2 2 0 FAM47 family 2-Hacid_dh_C PF02826.14 KLO05432.1 - 5.8e-52 175.4 0.0 8.5e-52 174.8 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 KLO05432.1 - 3.1e-30 104.3 0.1 3.5e-30 104.1 0.0 1.0 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 KLO05432.1 - 4.8e-07 29.7 0.1 9.4e-06 25.5 0.0 2.4 2 1 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase GFO_IDH_MocA PF01408.17 KLO05432.1 - 0.0026 18.2 0.0 0.036 14.5 0.0 2.2 2 0 0 2 2 2 1 Oxidoreductase family, NAD-binding Rossmann fold F420_oxidored PF03807.12 KLO05432.1 - 0.0027 18.1 0.3 0.014 15.8 0.0 2.3 3 0 0 3 3 3 1 NADP oxidoreductase coenzyme F420-dependent CoA_binding_2 PF13380.1 KLO05432.1 - 0.0098 16.0 0.1 0.023 14.8 0.1 1.6 1 0 0 1 1 1 1 CoA binding domain IlvN PF07991.7 KLO05432.1 - 0.018 14.4 0.0 0.032 13.6 0.0 1.5 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, catalytic domain UDPG_MGDP_dh_C PF03720.10 KLO05432.1 - 0.029 14.5 0.0 0.12 12.4 0.0 2.1 2 1 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain FAD_binding_3 PF01494.14 KLO05432.1 - 0.11 11.5 0.0 2.6 7.0 0.0 2.1 2 0 0 2 2 2 0 FAD binding domain HSP70 PF00012.15 KLO05433.1 - 0.0072 14.2 0.0 0.013 13.4 0.0 1.4 1 0 0 1 1 1 1 Hsp70 protein StbA PF06406.6 KLO05433.1 - 0.031 13.2 0.0 0.062 12.2 0.0 1.4 1 0 0 1 1 1 0 StbA protein Bac_DNA_binding PF00216.16 KLO05433.1 - 0.12 12.3 0.4 0.24 11.4 0.0 1.7 2 0 0 2 2 2 0 Bacterial DNA-binding protein SRP72 PF08492.7 KLO05434.1 - 5.2e-09 36.3 0.5 5.2e-09 36.3 0.4 2.7 3 0 0 3 3 3 1 SRP72 RNA-binding domain Apc3 PF12895.2 KLO05434.1 - 5.9e-07 29.5 1.9 0.00029 20.8 0.4 2.3 2 0 0 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_11 PF13414.1 KLO05434.1 - 0.00022 20.8 3.0 0.095 12.3 0.3 3.1 2 1 1 3 3 3 2 TPR repeat TPR_19 PF14559.1 KLO05434.1 - 0.0015 18.8 3.2 0.0032 17.7 0.2 2.6 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.1 KLO05434.1 - 0.0064 17.1 4.4 0.39 11.4 0.0 2.9 1 1 2 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.12 KLO05434.1 - 0.02 14.7 0.7 19 5.4 0.2 3.5 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_15 PF13429.1 KLO05434.1 - 0.056 12.5 5.4 0.67 8.9 0.4 2.2 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.1 KLO05434.1 - 0.1 13.3 0.4 21 6.0 0.0 3.4 2 1 0 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.1 KLO05434.1 - 0.62 10.0 7.3 1.9 8.4 0.3 3.1 2 1 1 3 3 3 0 Tetratricopeptide repeat His_Phos_2 PF00328.17 KLO05435.1 - 1.6e-06 27.7 0.1 0.0066 15.8 0.0 2.6 1 1 1 2 2 2 2 Histidine phosphatase superfamily (branch 2) ATP-synt_8 PF00895.15 KLO05435.1 - 0.1 12.8 0.1 0.24 11.6 0.1 1.6 1 0 0 1 1 1 0 ATP synthase protein 8 His_Phos_2 PF00328.17 KLO05436.1 - 5.7e-06 25.9 0.2 0.0001 21.7 0.1 2.1 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) BTB PF00651.26 KLO05437.1 - 1.1e-09 38.1 0.3 1.1e-09 38.1 0.2 1.8 2 0 0 2 2 2 1 BTB/POZ domain Skp1_POZ PF03931.10 KLO05437.1 - 0.0019 18.2 0.1 0.0044 17.0 0.1 1.6 1 0 0 1 1 1 1 Skp1 family, tetramerisation domain Abhydrolase_6 PF12697.2 KLO05438.1 - 1.4e-23 83.9 2.1 1.9e-23 83.5 1.5 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KLO05438.1 - 1.4e-08 34.6 0.5 3.2e-08 33.4 0.4 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KLO05438.1 - 4e-06 26.5 1.0 3.9e-05 23.3 0.7 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.3 KLO05438.1 - 0.0002 21.1 0.2 0.00046 19.9 0.0 1.7 2 0 0 2 2 2 1 Putative lysophospholipase Abhydrolase_6 PF12697.2 KLO05439.1 - 5.2e-22 78.8 0.8 7e-22 78.4 0.6 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KLO05439.1 - 3.1e-12 46.4 0.1 7.9e-12 45.1 0.1 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KLO05439.1 - 1.6e-11 44.2 1.1 7.4e-11 42.0 0.3 2.3 2 1 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.3 KLO05439.1 - 0.00045 20.0 0.1 0.00098 18.9 0.0 1.6 2 0 0 2 2 2 1 Putative lysophospholipase PTS-HPr PF00381.14 KLO05439.1 - 0.011 15.6 0.0 0.02 14.7 0.0 1.4 1 0 0 1 1 1 0 PTS HPr component phosphorylation site zf-MYND PF01753.13 KLO05440.1 - 5.2e-12 45.4 12.4 7.7e-12 44.8 8.6 1.3 1 0 0 1 1 1 1 MYND finger zf-HIT PF04438.11 KLO05440.1 - 3.4 7.3 6.9 5.7 6.6 4.8 1.3 1 0 0 1 1 1 0 HIT zinc finger AAA_18 PF13238.1 KLO05441.1 - 1.1e-07 32.1 0.0 1.8e-07 31.5 0.0 1.3 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 KLO05441.1 - 7.5e-07 29.1 0.0 8.3e-07 28.9 0.0 1.0 1 0 0 1 1 1 1 AAA domain Pkinase_Tyr PF07714.12 KLO05442.1 - 8.4e-39 133.1 0.0 5.5e-38 130.5 0.0 2.2 2 1 0 2 2 2 1 Protein tyrosine kinase Pkinase PF00069.20 KLO05442.1 - 1.6e-38 132.3 0.0 2.8e-38 131.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.1 KLO05442.1 - 6.2e-05 22.1 0.0 0.00011 21.2 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.6 KLO05442.1 - 0.0075 15.1 0.1 0.014 14.2 0.1 1.4 1 0 0 1 1 1 1 Seadornavirus VP7 APH PF01636.18 KLO05442.1 - 0.044 13.5 0.1 0.091 12.4 0.1 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family DUF4218 PF13960.1 KLO05444.1 - 0.0054 16.1 0.0 0.011 15.1 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4218) DUF2183 PF09949.4 KLO05444.1 - 0.018 14.9 0.0 2.4 8.1 0.0 3.0 2 1 1 3 3 3 0 Uncharacterized conserved protein (DUF2183) NOA36 PF06524.7 KLO05445.1 - 3.9 6.6 5.6 7.9 5.6 3.9 1.4 1 0 0 1 1 1 0 NOA36 protein POX PF07526.6 KLO05445.1 - 5.5 7.2 8.7 1.2 9.3 1.0 2.8 2 1 1 3 3 3 0 Associated with HOX CENP-O PF09496.5 KLO05446.1 - 0.018 15.2 0.2 0.078 13.2 0.1 2.1 2 0 0 2 2 2 0 Cenp-O kinetochore centromere component Zein-binding PF04576.10 KLO05446.1 - 0.068 13.3 3.3 0.18 11.9 2.3 1.6 1 0 0 1 1 1 0 Zein-binding BUD22 PF09073.5 KLO05446.1 - 1.1 8.3 12.4 0.029 13.4 3.3 2.0 2 0 0 2 2 2 0 BUD22 BBS1 PF14779.1 KLO05447.1 - 0.14 11.0 0.0 0.25 10.2 0.0 1.3 1 0 0 1 1 1 0 Ciliary BBSome complex subunit 1 Pkinase PF00069.20 KLO05450.1 - 1.7e-38 132.3 0.0 2e-38 132.0 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KLO05450.1 - 2.8e-36 124.9 0.0 4.2e-36 124.3 0.0 1.3 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 KLO05450.1 - 0.0076 16.0 0.0 0.011 15.4 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.17 KLO05450.1 - 0.016 14.5 0.0 0.023 14.0 0.0 1.3 1 0 0 1 1 1 0 RIO1 family EcKinase PF02958.15 KLO05450.1 - 0.13 11.4 0.0 0.21 10.6 0.0 1.3 1 0 0 1 1 1 0 Ecdysteroid kinase Helicase_C PF00271.26 KLO05452.1 - 1.1e-12 47.6 0.0 3.1e-12 46.1 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 KLO05452.1 - 8.2e-11 41.6 0.0 1.7e-10 40.6 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase SecA_DEAD PF07517.9 KLO05452.1 - 0.032 13.5 0.0 0.055 12.7 0.0 1.3 1 0 0 1 1 1 0 SecA DEAD-like domain T4SS-DNA_transf PF02534.9 KLO05452.1 - 0.099 11.2 0.1 0.16 10.5 0.0 1.2 1 0 0 1 1 1 0 Type IV secretory system Conjugative DNA transfer Pkinase PF00069.20 KLO05454.1 - 3.2e-28 98.5 0.0 4e-28 98.2 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KLO05454.1 - 2.3e-26 92.4 0.0 2.6e-26 92.2 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase C2-set_2 PF08205.7 KLO05454.1 - 0.0023 17.8 0.0 0.0039 17.0 0.0 1.3 1 0 0 1 1 1 1 CD80-like C2-set immunoglobulin domain APH PF01636.18 KLO05454.1 - 0.0027 17.4 0.0 0.0033 17.1 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.17 KLO05454.1 - 0.0043 16.4 0.0 0.0053 16.1 0.0 1.1 1 0 0 1 1 1 1 RIO1 family Kinase-like PF14531.1 KLO05454.1 - 0.05 12.5 0.0 0.061 12.2 0.0 1.1 1 0 0 1 1 1 0 Kinase-like Saccharop_dh PF03435.13 KLO05456.1 - 9.3e-110 367.2 0.2 2.1e-109 366.0 0.0 1.6 2 0 0 2 2 2 1 Saccharopine dehydrogenase Spermine_synth PF01564.12 KLO05456.1 - 1.1e-89 299.6 0.0 1.8e-89 298.8 0.0 1.3 1 0 0 1 1 1 1 Spermine/spermidine synthase Shikimate_DH PF01488.15 KLO05456.1 - 7.8e-08 32.4 0.3 2.7e-06 27.4 0.1 2.3 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase Methyltransf_31 PF13847.1 KLO05456.1 - 1.8e-05 24.3 0.0 0.00028 20.5 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 KLO05456.1 - 0.0012 19.3 0.0 0.0043 17.6 0.0 1.9 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KLO05456.1 - 0.005 17.2 0.1 0.033 14.6 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain F420_oxidored PF03807.12 KLO05456.1 - 0.0051 17.2 0.1 0.012 16.0 0.1 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent MTS PF05175.9 KLO05456.1 - 0.0064 15.8 0.0 0.021 14.2 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase small domain NAD_binding_10 PF13460.1 KLO05456.1 - 0.0065 16.4 0.4 0.015 15.3 0.3 1.6 1 0 0 1 1 1 1 NADH(P)-binding Methyltransf_11 PF08241.7 KLO05456.1 - 0.051 14.0 0.0 0.66 10.4 0.0 2.7 3 0 0 3 3 3 0 Methyltransferase domain Methyltransf_2 PF00891.13 KLO05456.1 - 0.097 11.8 0.1 0.19 10.8 0.0 1.4 1 0 0 1 1 1 0 O-methyltransferase FGGY_C PF02782.11 KLO05458.1 - 3.6e-06 26.7 0.0 1.7e-05 24.5 0.0 2.1 2 1 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain DUF2556 PF10831.3 KLO05462.1 - 6.1 6.5 6.6 1.6 8.4 0.1 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF2556) DUF368 PF04018.8 KLO05463.1 - 0.079 12.1 11.1 0.065 12.4 6.2 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF368) Syndecan PF01034.15 KLO05468.1 - 0.0014 18.2 0.0 0.0027 17.2 0.0 1.4 1 0 0 1 1 1 1 Syndecan domain SKG6 PF08693.5 KLO05469.1 - 0.00069 18.8 0.1 0.00069 18.8 0.1 1.7 2 0 0 2 2 2 1 Transmembrane alpha-helix domain Herpes_gE PF02480.11 KLO05469.1 - 0.025 12.8 0.0 0.043 12.0 0.0 1.3 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E Amnionless PF14828.1 KLO05469.1 - 0.056 11.9 0.0 0.092 11.2 0.0 1.3 1 0 0 1 1 1 0 Amnionless DUF202 PF02656.10 KLO05469.1 - 0.059 13.5 0.3 0.17 12.0 0.2 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF202) PDGLE PF13190.1 KLO05469.1 - 0.075 12.7 0.1 0.2 11.3 0.1 1.7 1 0 0 1 1 1 0 PDGLE domain DUF3042 PF11240.3 KLO05469.1 - 0.13 12.0 0.7 0.26 11.1 0.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3042) DSHCT PF08148.7 KLO05470.1 - 8.6e-57 191.2 0.0 1.8e-56 190.2 0.0 1.5 1 0 0 1 1 1 1 DSHCT (NUC185) domain DEAD PF00270.24 KLO05470.1 - 1.9e-21 76.2 0.1 4.2e-21 75.1 0.1 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KLO05470.1 - 3.3e-06 26.8 0.0 2.2e-05 24.2 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain rRNA_proc-arch PF13234.1 KLO05470.1 - 4.1e-05 22.8 0.0 8.4e-05 21.8 0.0 1.5 1 1 0 1 1 1 1 rRNA-processing arch domain ResIII PF04851.10 KLO05470.1 - 0.015 15.1 0.1 0.066 13.0 0.0 2.0 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit O-FucT PF10250.4 KLO05472.1 - 4.1e-06 26.1 0.0 7.4e-06 25.3 0.0 1.3 1 0 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase EPSP_synthase PF00275.15 KLO05473.1 - 0.073 11.4 0.0 0.17 10.3 0.0 1.5 2 0 0 2 2 2 0 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) WD40 PF00400.27 KLO05475.1 - 3.4e-66 216.9 34.0 1.7e-12 46.7 0.1 8.1 8 0 0 8 8 7 7 WD domain, G-beta repeat AAA_16 PF13191.1 KLO05475.1 - 4.8e-12 46.2 0.0 0.00014 21.9 0.1 3.0 2 0 0 2 2 2 2 AAA ATPase domain NACHT PF05729.7 KLO05475.1 - 1.1e-11 44.6 0.0 0.00023 20.8 0.0 3.8 3 2 0 3 3 3 2 NACHT domain Patatin PF01734.17 KLO05475.1 - 3.9e-10 39.9 0.3 2e-09 37.6 0.2 2.3 1 1 0 1 1 1 1 Patatin-like phospholipase AAA_22 PF13401.1 KLO05475.1 - 4.6e-10 39.7 0.0 9.4e-05 22.5 0.0 2.8 2 0 0 2 2 2 2 AAA domain NB-ARC PF00931.17 KLO05475.1 - 3.8e-08 32.5 0.0 9.2e-05 21.4 0.0 2.9 2 1 0 2 2 2 2 NB-ARC domain AAA_17 PF13207.1 KLO05475.1 - 9.2e-08 32.9 0.0 0.024 15.4 0.0 3.2 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.1 KLO05475.1 - 2.4e-07 31.1 0.0 0.0031 17.8 0.0 3.2 2 1 0 2 2 2 2 AAA domain AAA PF00004.24 KLO05475.1 - 3.1e-06 27.4 0.0 0.063 13.4 0.0 3.0 2 1 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.1 KLO05475.1 - 7.4e-06 25.9 0.0 0.17 11.7 0.0 2.8 2 0 0 2 2 2 2 AAA domain RNA_helicase PF00910.17 KLO05475.1 - 1.7e-05 24.9 0.0 0.17 12.0 0.0 3.3 3 0 0 3 3 3 2 RNA helicase KAP_NTPase PF07693.9 KLO05475.1 - 2.4e-05 23.4 0.5 0.0043 16.0 0.0 2.6 3 0 0 3 3 3 1 KAP family P-loop domain AAA_14 PF13173.1 KLO05475.1 - 2.7e-05 24.0 0.0 0.045 13.6 0.0 3.9 2 1 0 2 2 2 1 AAA domain AAA_25 PF13481.1 KLO05475.1 - 0.00026 20.4 0.0 0.48 9.8 0.0 3.0 3 0 0 3 3 2 2 AAA domain ABC_tran PF00005.22 KLO05475.1 - 0.00039 20.7 0.0 0.39 10.9 0.0 3.5 4 0 0 4 4 3 1 ABC transporter IstB_IS21 PF01695.12 KLO05475.1 - 0.0007 19.0 0.0 0.12 11.7 0.0 2.9 2 0 0 2 2 2 1 IstB-like ATP binding protein MMR_HSR1 PF01926.18 KLO05475.1 - 0.0046 16.8 0.0 1.8 8.5 0.0 3.2 3 0 0 3 3 2 1 50S ribosome-binding GTPase AAA_19 PF13245.1 KLO05475.1 - 0.0051 16.5 0.0 2.1 8.1 0.0 2.9 2 0 0 2 2 2 1 Part of AAA domain AAA_10 PF12846.2 KLO05475.1 - 0.0056 16.1 0.0 1.2 8.5 0.0 3.1 2 0 0 2 2 2 1 AAA-like domain Zeta_toxin PF06414.7 KLO05475.1 - 0.011 14.8 0.0 2.9 6.9 0.0 2.8 3 0 0 3 3 3 0 Zeta toxin PPV_E1_C PF00519.12 KLO05475.1 - 0.012 14.2 0.0 2.1 6.8 0.0 2.2 2 0 0 2 2 2 0 Papillomavirus helicase Arch_ATPase PF01637.13 KLO05475.1 - 0.016 14.9 0.0 0.24 11.0 0.0 2.6 3 0 0 3 3 2 0 Archaeal ATPase Miro PF08477.8 KLO05475.1 - 0.016 15.6 0.0 2.6 8.5 0.0 3.3 3 0 0 3 3 3 0 Miro-like protein AAA_28 PF13521.1 KLO05475.1 - 0.021 14.8 0.0 2.5 8.0 0.0 2.5 2 0 0 2 2 2 0 AAA domain APS_kinase PF01583.15 KLO05475.1 - 0.021 14.4 0.0 6.8 6.3 0.0 2.6 2 0 0 2 2 2 0 Adenylylsulphate kinase AAA_24 PF13479.1 KLO05475.1 - 0.023 14.2 0.0 3.1 7.3 0.0 2.4 2 0 0 2 2 2 0 AAA domain Rib_hydrolayse PF02267.12 KLO05475.1 - 0.036 13.3 0.0 0.086 12.1 0.0 1.5 1 0 0 1 1 1 0 ADP-ribosyl cyclase DUF258 PF03193.11 KLO05475.1 - 0.05 12.7 0.0 0.46 9.6 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function, DUF258 AAA_11 PF13086.1 KLO05475.1 - 0.069 12.7 0.0 9.5 5.7 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.1 KLO05475.1 - 0.071 12.6 0.0 2.1 7.9 0.0 2.5 2 0 0 2 2 2 0 P-loop containing region of AAA domain Nbas_N PF15492.1 KLO05475.1 - 0.077 12.0 3.4 10 5.1 0.0 4.1 2 2 3 5 5 5 0 Neuroblastoma-amplified sequence, N terminal ADK PF00406.17 KLO05475.1 - 0.14 11.9 0.2 22 4.9 0.0 3.1 3 0 0 3 3 3 0 Adenylate kinase AAA_5 PF07728.9 KLO05475.1 - 0.16 11.7 0.0 3.3 7.4 0.0 2.5 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.16 KLO05475.1 - 0.26 10.4 0.0 11 5.0 0.0 2.5 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI Patatin PF01734.17 KLO05476.1 - 2.9e-13 50.2 0.1 3.1e-13 50.1 0.0 1.1 1 0 0 1 1 1 1 Patatin-like phospholipase NUC202 PF08166.7 KLO05476.1 - 0.15 11.9 0.0 0.28 11.0 0.0 1.4 1 0 0 1 1 1 0 NUC202 domain Spt5-NGN PF03439.8 KLO05479.1 - 8.3e-13 47.9 0.0 2.1e-12 46.5 0.0 1.8 1 0 0 1 1 1 1 Early transcription elongation factor of RNA pol II, NGN section DHC PF09626.5 KLO05479.1 - 0.00099 19.7 0.0 0.0027 18.3 0.0 1.7 1 0 0 1 1 1 1 Dihaem cytochrome c KOW PF00467.24 KLO05479.1 - 0.0091 15.6 0.8 0.0091 15.6 0.6 5.0 5 0 0 5 5 5 1 KOW motif DUF4438 PF14505.1 KLO05479.1 - 0.87 8.3 4.0 21 3.7 0.1 3.6 4 1 1 5 5 5 0 Domain of unknown function (DUF4438) Spt5_N PF11942.3 KLO05482.1 - 0.0046 17.5 12.7 0.0046 17.5 8.8 3.3 2 1 1 3 3 3 1 Spt5 transcription elongation factor, acidic N-terminal DUF3480 PF11979.3 KLO05482.1 - 0.0078 14.8 0.9 0.013 14.1 0.6 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3480) RNA_pol_3_Rpc31 PF11705.3 KLO05482.1 - 0.092 12.6 29.5 0.37 10.6 6.2 2.3 2 0 0 2 2 2 0 DNA-directed RNA polymerase III subunit Rpc31 Spt5_N PF11942.3 KLO05483.1 - 0.014 15.9 11.3 0.014 15.9 7.8 2.9 2 1 1 3 3 3 0 Spt5 transcription elongation factor, acidic N-terminal AAA PF00004.24 KLO05487.1 - 1.5e-85 284.0 0.0 9.2e-47 158.5 0.0 3.1 2 1 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) CDC48_N PF02359.13 KLO05487.1 - 1.5e-14 53.6 0.1 7.4e-14 51.4 0.1 2.2 2 0 0 2 2 1 1 Cell division protein 48 (CDC48), N-terminal domain RuvB_N PF05496.7 KLO05487.1 - 5.5e-14 51.7 0.0 1.5e-05 24.1 0.0 3.3 3 0 0 3 3 3 2 Holliday junction DNA helicase ruvB N-terminus AAA_17 PF13207.1 KLO05487.1 - 1.8e-12 48.1 0.0 5.1e-05 24.0 0.0 2.9 2 1 0 2 2 2 2 AAA domain AAA_33 PF13671.1 KLO05487.1 - 7.5e-12 45.3 0.0 3.1e-05 23.8 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_5 PF07728.9 KLO05487.1 - 8.2e-12 45.0 0.1 0.00076 19.2 0.0 4.6 2 2 1 3 3 3 2 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 KLO05487.1 - 1e-11 45.0 0.0 2.4e-05 24.2 0.0 2.6 2 1 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_22 PF13401.1 KLO05487.1 - 2.7e-11 43.7 0.0 0.0026 17.9 0.0 4.0 2 2 1 3 3 3 2 AAA domain CDC48_2 PF02933.12 KLO05487.1 - 2.2e-10 40.0 0.0 4.1e-10 39.1 0.0 1.5 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), domain 2 AAA_16 PF13191.1 KLO05487.1 - 5.6e-10 39.5 0.0 0.00088 19.2 0.0 2.9 2 2 0 2 2 2 2 AAA ATPase domain TIP49 PF06068.8 KLO05487.1 - 1.5e-09 37.0 0.1 0.00076 18.2 0.0 2.7 3 0 0 3 3 2 2 TIP49 C-terminus IstB_IS21 PF01695.12 KLO05487.1 - 1.2e-08 34.6 0.1 0.0031 16.9 0.0 2.6 3 0 0 3 3 2 2 IstB-like ATP binding protein AAA_19 PF13245.1 KLO05487.1 - 2.4e-08 33.6 0.2 0.0072 16.0 0.0 2.8 2 0 0 2 2 2 2 Part of AAA domain AAA_14 PF13173.1 KLO05487.1 - 3.8e-08 33.2 0.0 0.0014 18.5 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.1 KLO05487.1 - 6.1e-08 33.0 0.0 0.014 15.7 0.0 2.6 2 0 0 2 2 2 2 AAA domain Zeta_toxin PF06414.7 KLO05487.1 - 1.2e-07 31.0 0.0 0.014 14.5 0.0 2.4 2 0 0 2 2 2 2 Zeta toxin AAA_25 PF13481.1 KLO05487.1 - 3.6e-07 29.7 2.7 0.012 14.9 0.0 3.9 2 2 2 4 4 4 1 AAA domain RNA_helicase PF00910.17 KLO05487.1 - 4.8e-07 29.9 0.0 0.013 15.6 0.0 2.7 2 0 0 2 2 2 2 RNA helicase Mg_chelatase PF01078.16 KLO05487.1 - 8.7e-07 28.2 0.2 0.019 14.1 0.0 2.6 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI KaiC PF06745.8 KLO05487.1 - 9.2e-07 28.1 0.3 0.12 11.4 0.1 3.3 2 1 1 3 3 3 2 KaiC ResIII PF04851.10 KLO05487.1 - 1.1e-06 28.6 0.0 0.00083 19.2 0.0 2.3 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_28 PF13521.1 KLO05487.1 - 1.1e-06 28.7 0.0 0.065 13.1 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_24 PF13479.1 KLO05487.1 - 2.9e-06 27.0 0.0 0.087 12.3 0.0 3.2 3 0 0 3 3 3 2 AAA domain Parvo_NS1 PF01057.12 KLO05487.1 - 4.9e-06 25.6 0.1 0.0068 15.3 0.0 2.2 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 Sigma54_activat PF00158.21 KLO05487.1 - 9.5e-06 25.1 0.0 0.28 10.6 0.0 3.2 2 1 0 2 2 2 2 Sigma-54 interaction domain Sigma54_activ_2 PF14532.1 KLO05487.1 - 1.8e-05 24.8 0.0 0.14 12.1 0.0 2.7 3 0 0 3 3 2 2 Sigma-54 interaction domain ABC_tran PF00005.22 KLO05487.1 - 2.8e-05 24.4 0.0 0.093 13.0 0.0 3.1 2 1 0 2 2 2 1 ABC transporter PhoH PF02562.11 KLO05487.1 - 3.2e-05 23.2 0.2 0.19 10.9 0.0 2.4 2 0 0 2 2 2 2 PhoH-like protein AAA_11 PF13086.1 KLO05487.1 - 4e-05 23.2 0.0 0.07 12.6 0.0 2.4 2 0 0 2 2 2 2 AAA domain DUF2075 PF09848.4 KLO05487.1 - 7.4e-05 21.8 0.0 0.3 10.0 0.0 2.3 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2075) AAA_3 PF07726.6 KLO05487.1 - 0.00012 21.6 0.0 0.48 10.0 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) DUF815 PF05673.8 KLO05487.1 - 0.0003 19.8 0.0 0.019 13.8 0.0 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_30 PF13604.1 KLO05487.1 - 0.00039 20.0 0.0 0.87 9.1 0.0 2.5 2 0 0 2 2 2 2 AAA domain Arch_ATPase PF01637.13 KLO05487.1 - 0.00041 20.1 0.0 0.61 9.7 0.0 2.6 2 1 0 2 2 2 1 Archaeal ATPase NACHT PF05729.7 KLO05487.1 - 0.00043 19.9 0.1 0.41 10.2 0.0 3.1 4 0 0 4 4 2 1 NACHT domain Viral_helicase1 PF01443.13 KLO05487.1 - 0.0006 19.4 0.0 0.17 11.3 0.0 2.4 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase T2SE PF00437.15 KLO05487.1 - 0.00078 18.4 0.0 0.2 10.4 0.0 2.4 2 0 0 2 2 2 1 Type II/IV secretion system protein NB-ARC PF00931.17 KLO05487.1 - 0.00088 18.2 0.0 0.21 10.4 0.0 2.3 2 0 0 2 2 2 1 NB-ARC domain NTPase_1 PF03266.10 KLO05487.1 - 0.0014 18.3 0.2 0.96 9.1 0.0 3.4 3 0 0 3 3 3 1 NTPase Bac_DnaA PF00308.13 KLO05487.1 - 0.0019 17.9 0.0 0.63 9.6 0.0 2.6 2 1 0 2 2 2 1 Bacterial dnaA protein AAA_10 PF12846.2 KLO05487.1 - 0.0029 17.1 0.7 4.2 6.7 0.0 3.8 3 1 1 4 4 4 0 AAA-like domain ATP-synt_ab PF00006.20 KLO05487.1 - 0.0051 16.3 0.0 1.9 7.9 0.0 2.3 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain IPT PF01745.11 KLO05487.1 - 0.0068 15.6 0.1 0.41 9.7 0.0 2.2 2 0 0 2 2 2 1 Isopentenyl transferase AAA_23 PF13476.1 KLO05487.1 - 0.026 14.8 0.0 4.4 7.5 0.0 2.5 2 0 0 2 2 2 0 AAA domain UPF0079 PF02367.12 KLO05487.1 - 0.037 13.6 0.1 2.8 7.5 0.0 2.4 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 Cytidylate_kin2 PF13189.1 KLO05487.1 - 0.047 13.6 0.0 1 9.2 0.0 2.3 2 0 0 2 2 2 0 Cytidylate kinase-like family SKI PF01202.17 KLO05487.1 - 0.058 13.2 0.1 6.1 6.6 0.0 2.6 3 0 0 3 3 2 0 Shikimate kinase KTI12 PF08433.5 KLO05487.1 - 0.059 12.5 0.0 6.1 5.9 0.0 2.3 2 0 0 2 2 2 0 Chromatin associated protein KTI12 UFD1 PF03152.9 KLO05487.1 - 0.084 12.0 0.0 0.16 11.0 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin fusion degradation protein UFD1 KAP_NTPase PF07693.9 KLO05487.1 - 0.095 11.6 0.1 1.9 7.4 0.0 2.6 2 2 1 3 3 3 0 KAP family P-loop domain Zot PF05707.7 KLO05487.1 - 0.11 11.9 0.1 21 4.4 0.0 3.2 2 1 0 2 2 2 0 Zonular occludens toxin (Zot) MobB PF03205.9 KLO05487.1 - 0.12 12.1 0.0 7.6 6.2 0.0 2.7 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B PPV_E1_C PF00519.12 KLO05487.1 - 0.34 9.4 0.0 4.6 5.7 0.0 2.0 2 0 0 2 2 2 0 Papillomavirus helicase Cyclin_N PF00134.18 KLO05488.1 - 4.4e-08 32.7 0.0 7e-08 32.0 0.0 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.6 KLO05488.1 - 0.00016 22.0 0.0 0.00022 21.6 0.0 1.3 1 0 0 1 1 1 1 Cyclin Kdo PF06293.9 KLO05489.1 - 5.8e-06 25.5 0.0 2.5e-05 23.4 0.0 2.0 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.20 KLO05489.1 - 9.8e-06 24.8 0.1 4.3e-05 22.7 0.1 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KLO05489.1 - 0.077 12.0 0.0 0.17 10.9 0.0 1.5 1 0 0 1 1 1 0 Protein tyrosine kinase APH PF01636.18 KLO05489.1 - 0.11 12.2 0.4 0.29 10.8 0.0 1.8 2 0 0 2 2 2 0 Phosphotransferase enzyme family COesterase PF00135.23 KLO05491.1 - 7.9e-83 278.9 0.0 9.5e-83 278.7 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 KLO05491.1 - 1.2e-05 24.9 0.1 4.1e-05 23.2 0.1 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KLO05491.1 - 0.0013 18.5 0.0 0.0025 17.6 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family F-box PF00646.28 KLO05493.1 - 0.00015 21.2 0.0 0.00023 20.7 0.0 1.3 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 KLO05493.1 - 0.056 13.1 0.0 0.076 12.7 0.0 1.3 1 0 0 1 1 1 0 F-box-like MIS13 PF08202.6 KLO05495.1 - 7.7e-25 87.5 5.7 1e-24 87.1 2.3 2.1 2 0 0 2 2 2 1 Mis12-Mtw1 protein family DIOX_N PF14226.1 KLO05496.1 - 1.6e-13 51.1 0.0 2.9e-13 50.3 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 KLO05496.1 - 4.7e-13 49.2 0.0 1.3e-12 47.8 0.0 1.7 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily C2 PF00168.25 KLO05497.1 - 1.6e-11 43.8 0.1 2.6e-11 43.2 0.0 1.3 1 0 0 1 1 1 1 C2 domain 7kD_DNA_binding PF02294.13 KLO05497.1 - 0.15 11.7 0.1 0.27 10.9 0.1 1.4 1 0 0 1 1 1 0 7kD DNA-binding domain Rod-binding PF10135.4 KLO05497.1 - 0.34 10.9 3.9 0.6 10.1 1.4 2.3 2 1 0 2 2 2 0 Rod binding protein CCDC50_N PF15295.1 KLO05497.1 - 9.4 6.1 10.5 13 5.6 5.2 2.1 1 1 1 2 2 2 0 Coiled-coil domain-containing protein 50 N-terminus F-box PF00646.28 KLO05498.1 - 0.0005 19.6 0.0 0.0015 18.0 0.0 1.9 1 0 0 1 1 1 1 F-box domain Cellulase PF00150.13 KLO05501.1 - 8.6e-26 90.7 5.5 1.1e-25 90.3 3.8 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) CBM_1 PF00734.13 KLO05501.1 - 1.6e-11 43.6 4.3 4.1e-11 42.3 3.0 1.8 1 0 0 1 1 1 1 Fungal cellulose binding domain Cellulase-like PF12876.2 KLO05501.1 - 2.6e-07 30.9 0.0 6.4e-07 29.7 0.0 1.7 1 0 0 1 1 1 1 Sugar-binding cellulase-like Glyco_hydro_2_C PF02836.12 KLO05501.1 - 0.02 13.8 0.0 0.05 12.5 0.0 1.6 1 1 0 1 1 1 0 Glycosyl hydrolases family 2, TIM barrel domain Glyco_hydro_44 PF12891.2 KLO05501.1 - 0.023 14.1 0.0 0.048 13.1 0.0 1.4 1 0 0 1 1 1 0 Glycoside hydrolase family 44 Glyco_hydro_10 PF00331.15 KLO05501.1 - 0.032 13.2 0.1 0.058 12.4 0.1 1.4 1 0 0 1 1 1 0 Glycosyl hydrolase family 10 Ring_hydroxyl_A PF00848.14 KLO05502.1 - 1.2e-34 119.7 0.5 5.7e-34 117.5 0.5 1.9 2 1 0 2 2 2 1 Ring hydroxylating alpha subunit (catalytic domain) Rieske PF00355.21 KLO05502.1 - 5.6e-13 48.2 0.0 1e-12 47.4 0.0 1.4 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Pkinase_Tyr PF07714.12 KLO05503.1 - 7.1e-42 143.2 0.0 1.1e-41 142.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 KLO05503.1 - 4.1e-41 140.8 0.0 7.4e-41 140.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.18 KLO05503.1 - 6.1e-06 26.1 0.1 1.8e-05 24.5 0.0 1.9 1 0 0 1 1 1 1 Phosphotransferase enzyme family DUF4238 PF14022.1 KLO05503.1 - 0.00033 20.0 0.0 0.00053 19.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF4238) Fructosamin_kin PF03881.9 KLO05503.1 - 0.017 14.1 0.0 0.028 13.4 0.0 1.2 1 0 0 1 1 1 0 Fructosamine kinase DUF912 PF06024.7 KLO05504.1 - 0.048 13.7 0.0 0.094 12.7 0.0 1.4 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Amnionless PF14828.1 KLO05504.1 - 0.07 11.6 0.0 0.098 11.1 0.0 1.2 1 0 0 1 1 1 0 Amnionless Iso_dh PF00180.15 KLO05505.1 - 2.4e-74 250.3 0.0 2.9e-74 250.1 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase zf-C2H2 PF00096.21 KLO05510.1 - 4e-09 36.2 7.5 0.017 15.4 0.2 3.7 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KLO05510.1 - 4.2e-06 26.7 7.6 0.31 11.4 0.0 3.6 3 0 0 3 3 3 3 C2H2-type zinc finger zf-H2C2_2 PF13465.1 KLO05510.1 - 0.019 15.2 12.5 3.1 8.2 0.7 3.7 4 0 0 4 4 4 0 Zinc-finger double domain zf-met PF12874.2 KLO05510.1 - 0.022 14.9 0.6 14 6.0 0.0 3.1 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 KLO05510.1 - 0.21 11.8 2.3 21 5.4 0.0 2.9 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 KLO05510.1 - 0.76 9.7 6.3 4.3 7.3 0.8 3.0 3 0 0 3 3 3 0 C2H2-type zinc finger zf-H2C2_5 PF13909.1 KLO05510.1 - 2.1 8.7 8.0 1.9 8.8 0.7 3.4 3 0 0 3 3 3 0 C2H2-type zinc-finger domain WD40 PF00400.27 KLO05511.1 - 2.6e-68 223.6 36.3 9.2e-11 41.1 0.2 7.9 7 0 0 7 7 7 7 WD domain, G-beta repeat AAA_22 PF13401.1 KLO05511.1 - 5.1e-13 49.3 0.0 6.3e-06 26.3 0.0 3.1 2 0 0 2 2 2 2 AAA domain NACHT PF05729.7 KLO05511.1 - 2e-10 40.5 0.0 1.6e-05 24.6 0.0 3.3 2 2 0 2 2 2 2 NACHT domain AAA_16 PF13191.1 KLO05511.1 - 4.1e-10 39.9 0.0 0.00028 20.9 0.0 2.9 2 0 0 2 2 2 2 AAA ATPase domain AAA PF00004.24 KLO05511.1 - 7.7e-09 35.8 0.0 0.0038 17.4 0.0 2.9 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 KLO05511.1 - 3.5e-08 34.3 0.0 0.019 15.7 0.0 3.6 4 0 0 4 4 2 2 AAA domain NB-ARC PF00931.17 KLO05511.1 - 1.3e-07 30.7 0.0 9.8e-05 21.3 0.0 3.4 4 0 0 4 4 4 1 NB-ARC domain AAA_25 PF13481.1 KLO05511.1 - 7e-07 28.8 0.1 0.0082 15.5 0.0 3.1 3 0 0 3 3 2 2 AAA domain AAA_18 PF13238.1 KLO05511.1 - 8.2e-07 29.3 0.0 0.059 13.6 0.0 2.8 2 0 0 2 2 2 2 AAA domain APS_kinase PF01583.15 KLO05511.1 - 1.3e-06 28.1 0.0 0.023 14.3 0.0 2.6 2 0 0 2 2 2 2 Adenylylsulphate kinase RNA_helicase PF00910.17 KLO05511.1 - 2.1e-06 27.8 0.0 0.11 12.6 0.0 2.9 2 0 0 2 2 2 2 RNA helicase Zeta_toxin PF06414.7 KLO05511.1 - 2.7e-06 26.6 0.0 0.064 12.3 0.0 2.5 2 0 0 2 2 2 2 Zeta toxin Nbas_N PF15492.1 KLO05511.1 - 1.9e-05 23.9 1.3 0.085 11.9 0.0 3.8 3 1 1 4 4 4 1 Neuroblastoma-amplified sequence, N terminal AAA_19 PF13245.1 KLO05511.1 - 2.1e-05 24.1 0.0 0.021 14.5 0.0 2.6 2 0 0 2 2 2 1 Part of AAA domain AAA_33 PF13671.1 KLO05511.1 - 2.2e-05 24.3 0.0 0.12 12.2 0.0 2.8 2 0 0 2 2 2 2 AAA domain DUF2075 PF09848.4 KLO05511.1 - 2.8e-05 23.2 0.0 0.17 10.8 0.0 2.3 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2075) MobB PF03205.9 KLO05511.1 - 0.00021 21.0 0.0 0.0018 17.9 0.0 2.5 3 0 0 3 3 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_28 PF13521.1 KLO05511.1 - 0.00033 20.6 0.0 0.32 10.9 0.0 2.7 2 0 0 2 2 2 1 AAA domain RuvB_N PF05496.7 KLO05511.1 - 0.0016 17.5 0.0 0.22 10.5 0.0 2.3 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_14 PF13173.1 KLO05511.1 - 0.0022 17.8 0.0 4.9 7.0 0.0 3.7 3 2 0 3 3 2 0 AAA domain Viral_helicase1 PF01443.13 KLO05511.1 - 0.0033 16.9 0.0 2.2 7.7 0.0 2.4 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase IstB_IS21 PF01695.12 KLO05511.1 - 0.0039 16.6 0.0 2.4 7.5 0.0 2.5 2 0 0 2 2 2 1 IstB-like ATP binding protein ABC_tran PF00005.22 KLO05511.1 - 0.0052 17.0 0.0 1.8 8.8 0.0 2.7 2 0 0 2 2 2 1 ABC transporter NTPase_1 PF03266.10 KLO05511.1 - 0.006 16.3 0.0 0.13 11.9 0.0 2.6 3 0 0 3 3 2 1 NTPase PD40 PF07676.7 KLO05511.1 - 0.0075 15.9 1.9 46 3.8 0.0 5.4 6 0 0 6 6 5 0 WD40-like Beta Propeller Repeat TIP49 PF06068.8 KLO05511.1 - 0.0077 14.9 0.0 3.2 6.3 0.0 2.2 2 0 0 2 2 2 0 TIP49 C-terminus KTI12 PF08433.5 KLO05511.1 - 0.0096 15.1 0.0 0.7 9.0 0.0 2.6 3 0 0 3 3 2 1 Chromatin associated protein KTI12 Nucleoporin_N PF08801.6 KLO05511.1 - 0.012 14.3 0.3 0.15 10.8 0.1 2.7 1 1 1 2 2 2 0 Nup133 N terminal like ArgK PF03308.11 KLO05511.1 - 0.017 13.9 0.0 1.5 7.5 0.0 2.2 2 0 0 2 2 2 0 ArgK protein Rad17 PF03215.10 KLO05511.1 - 0.032 12.9 0.0 3.3 6.2 0.0 2.2 2 0 0 2 2 2 0 Rad17 cell cycle checkpoint protein AAA_10 PF12846.2 KLO05511.1 - 0.033 13.6 0.0 1.4 8.2 0.0 2.7 2 0 0 2 2 2 0 AAA-like domain AAA_30 PF13604.1 KLO05511.1 - 0.039 13.5 0.1 0.88 9.1 0.0 2.3 2 0 0 2 2 2 0 AAA domain Torsin PF06309.6 KLO05511.1 - 0.04 13.8 0.0 13 5.6 0.0 2.7 2 0 0 2 2 2 0 Torsin FtsK_SpoIIIE PF01580.13 KLO05511.1 - 0.054 12.9 0.0 6.4 6.2 0.0 2.6 2 0 0 2 2 2 0 FtsK/SpoIIIE family CbiA PF01656.18 KLO05511.1 - 0.063 12.6 0.0 1.7 8.0 0.0 2.5 2 0 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain Parvo_NS1 PF01057.12 KLO05511.1 - 0.069 12.0 0.0 3.3 6.4 0.0 2.3 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 Arch_ATPase PF01637.13 KLO05511.1 - 0.077 12.6 0.0 0.9 9.1 0.0 2.6 3 0 0 3 3 2 0 Archaeal ATPase ADK PF00406.17 KLO05511.1 - 0.08 12.8 0.1 2.5 7.9 0.0 2.6 2 0 0 2 2 2 0 Adenylate kinase AAA_5 PF07728.9 KLO05511.1 - 0.092 12.4 0.0 8.3 6.1 0.0 2.7 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) TrwB_AAD_bind PF10412.4 KLO05511.1 - 0.094 11.3 0.0 3 6.3 0.0 2.3 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain SRP54 PF00448.17 KLO05511.1 - 0.13 11.7 0.0 0.59 9.5 0.0 2.1 3 0 0 3 3 2 0 SRP54-type protein, GTPase domain Mg_chelatase PF01078.16 KLO05511.1 - 0.14 11.2 0.0 19 4.3 0.0 2.3 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI PhoH PF02562.11 KLO05511.1 - 0.17 11.0 0.0 7.8 5.6 0.0 2.4 2 0 0 2 2 2 0 PhoH-like protein AAA_11 PF13086.1 KLO05511.1 - 0.19 11.2 0.0 8.9 5.8 0.0 2.5 2 0 0 2 2 2 0 AAA domain Zot PF05707.7 KLO05511.1 - 0.2 11.1 0.0 6.2 6.2 0.0 2.8 3 0 0 3 3 3 0 Zonular occludens toxin (Zot) ResIII PF04851.10 KLO05511.1 - 0.24 11.2 0.0 4.3 7.1 0.0 2.3 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit KAP_NTPase PF07693.9 KLO05511.1 - 0.39 9.6 4.6 8.7 5.2 0.1 3.6 3 1 0 4 4 4 0 KAP family P-loop domain zf-TRAF PF02176.13 KLO05513.1 - 0.98 9.8 6.3 0.9 9.9 0.5 2.2 2 0 0 2 2 2 0 TRAF-type zinc finger Oxidored_FMN PF00724.15 KLO05514.1 - 1e-08 34.5 0.0 1.2e-08 34.3 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Abhydrolase_3 PF07859.8 KLO05515.1 - 2.5e-29 102.3 0.0 4.3e-29 101.6 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF2424 PF10340.4 KLO05515.1 - 1.4e-15 56.8 0.0 3.1e-14 52.4 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF2424) Abhydrolase_5 PF12695.2 KLO05515.1 - 0.0024 17.6 0.0 0.0041 16.8 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KLO05515.1 - 0.025 14.4 1.0 0.048 13.5 0.7 1.6 1 1 0 1 1 1 0 Alpha/beta hydrolase family Thioesterase PF00975.15 KLO05515.1 - 0.094 12.9 0.0 0.16 12.1 0.0 1.3 1 0 0 1 1 1 0 Thioesterase domain Chlorophyllase2 PF12740.2 KLO05515.1 - 0.14 11.0 0.0 0.21 10.4 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase enzyme DUF2920 PF11144.3 KLO05515.1 - 0.3 10.0 0.3 1.5 7.7 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2920) Abhydrolase_3 PF07859.8 KLO05516.1 - 1.9e-27 96.2 0.0 2.8e-27 95.6 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF2424 PF10340.4 KLO05516.1 - 1.8e-13 49.8 0.0 7.7e-12 44.5 0.0 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF2424) Abhydrolase_5 PF12695.2 KLO05516.1 - 8.7e-05 22.2 0.0 0.00028 20.6 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Fascin PF06268.8 KLO05517.1 - 0.12 12.4 0.0 0.37 10.8 0.0 1.8 1 0 0 1 1 1 0 Fascin domain FAD_binding_3 PF01494.14 KLO05518.1 - 2.3e-14 53.2 0.1 2e-08 33.7 0.0 2.4 2 1 0 2 2 2 2 FAD binding domain DAO PF01266.19 KLO05518.1 - 2.8e-10 39.6 0.2 1.3e-06 27.5 0.0 2.7 3 0 0 3 3 3 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 KLO05518.1 - 1.5e-08 33.9 0.2 2.4e-08 33.2 0.2 1.3 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 KLO05518.1 - 1.3e-07 31.4 0.0 3.3e-07 30.2 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.9 KLO05518.1 - 1.6e-06 26.8 0.4 1.4e-05 23.8 0.2 2.0 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox_2 PF07992.9 KLO05518.1 - 3.1e-06 27.2 0.2 8.6e-06 25.7 0.1 1.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 KLO05518.1 - 0.00033 19.8 0.0 0.00052 19.2 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 KLO05518.1 - 0.00038 20.7 0.5 0.0041 17.4 0.3 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 KLO05518.1 - 0.00061 18.5 0.4 0.16 10.5 0.0 2.1 2 0 0 2 2 2 2 Tryptophan halogenase GIDA PF01134.17 KLO05518.1 - 0.00073 18.5 0.2 0.001 18.0 0.2 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A Thi4 PF01946.12 KLO05518.1 - 0.0033 16.5 0.1 0.0057 15.7 0.1 1.3 1 0 0 1 1 1 1 Thi4 family Lycopene_cycl PF05834.7 KLO05518.1 - 0.004 16.1 0.2 0.021 13.7 0.1 1.9 1 1 0 1 1 1 1 Lycopene cyclase protein UDPG_MGDP_dh_N PF03721.9 KLO05518.1 - 0.01 15.2 0.2 0.016 14.5 0.1 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Pyr_redox_3 PF13738.1 KLO05518.1 - 0.026 14.5 0.0 0.054 13.5 0.0 1.5 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.19 KLO05518.1 - 0.031 13.3 0.0 1.1 8.2 0.0 2.3 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase AlaDh_PNT_C PF01262.16 KLO05518.1 - 0.061 12.8 0.1 0.12 11.9 0.0 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain 3HCDH_N PF02737.13 KLO05518.1 - 0.2 11.3 0.1 0.31 10.6 0.1 1.2 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Abhydrolase_3 PF07859.8 KLO05519.1 - 6.2e-25 88.0 0.0 9.8e-25 87.3 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF2424 PF10340.4 KLO05519.1 - 8.1e-17 60.9 0.0 1.5e-16 60.0 0.0 1.3 2 0 0 2 2 2 1 Protein of unknown function (DUF2424) Abhydrolase_6 PF12697.2 KLO05519.1 - 0.0016 18.3 0.4 0.0036 17.2 0.1 1.7 2 1 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KLO05519.1 - 0.0021 17.8 0.0 0.0032 17.2 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family BTB PF00651.26 KLO05520.1 - 1.8e-05 24.6 0.8 8.9e-05 22.4 0.6 2.1 1 1 0 1 1 1 1 BTB/POZ domain Pkinase PF00069.20 KLO05521.1 - 1e-34 119.8 0.0 1.8e-34 119.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KLO05521.1 - 4e-34 117.8 0.0 7.7e-34 116.9 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 KLO05521.1 - 0.0062 16.2 0.0 0.035 13.8 0.0 2.2 2 0 0 2 2 2 1 Phosphotransferase enzyme family YlbD_coat PF14071.1 KLO05521.1 - 0.019 15.0 3.7 0.21 11.6 2.5 2.3 2 0 0 2 2 2 0 Putative coat protein Apc4 PF12896.2 KLO05521.1 - 0.076 12.3 2.7 0.4 9.9 0.9 2.2 1 1 1 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 4 Abhydrolase_3 PF07859.8 KLO05523.1 - 1e-26 93.8 0.1 1.4e-26 93.3 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF2424 PF10340.4 KLO05523.1 - 8.1e-17 60.9 0.0 8.3e-15 54.3 0.0 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF2424) Abhydrolase_5 PF12695.2 KLO05523.1 - 0.048 13.4 0.0 0.066 12.9 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family XdhC_C PF13478.1 KLO05524.1 - 0.38 11.0 1.4 2.4 8.4 1.0 2.0 1 1 0 1 1 1 0 XdhC Rossmann domain DUF342 PF03961.8 KLO05524.1 - 0.69 8.2 5.1 0.75 8.1 3.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) BAR_2 PF10455.4 KLO05525.1 - 0.074 11.9 1.3 0.097 11.5 0.9 1.1 1 0 0 1 1 1 0 Bin/amphiphysin/Rvs domain for vesicular trafficking Spc24 PF08286.6 KLO05525.1 - 0.088 12.5 0.9 0.15 11.7 0.6 1.3 1 0 0 1 1 1 0 Spc24 subunit of Ndc80 Sec2p PF06428.6 KLO05525.1 - 0.31 10.9 2.9 0.13 12.0 0.4 1.6 2 0 0 2 2 2 0 GDP/GTP exchange factor Sec2p HALZ PF02183.13 KLO05525.1 - 3.5 7.3 8.1 2 8.2 3.5 1.9 2 0 0 2 2 2 0 Homeobox associated leucine zipper Glyco_hydro_18 PF00704.23 KLO05526.1 - 2.7e-39 135.5 0.8 5.4e-39 134.5 0.6 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 LysM PF01476.15 KLO05526.1 - 7.6e-13 48.1 0.4 1.7e-05 24.5 0.0 2.7 2 0 0 2 2 2 2 LysM domain Chitin_bind_1 PF00187.14 KLO05526.1 - 9.8e-10 38.2 12.4 2.9e-09 36.7 8.6 1.9 1 0 0 1 1 1 1 Chitin recognition protein DUF2092 PF09865.4 KLO05526.1 - 0.2 10.7 0.0 0.35 9.8 0.0 1.3 1 0 0 1 1 1 0 Predicted periplasmic protein (DUF2092) Apolipoprotein PF01442.13 KLO05527.1 - 0.025 14.0 6.4 0.037 13.5 4.4 1.2 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain DUF1351 PF07083.6 KLO05528.1 - 0.00042 19.9 4.2 0.00053 19.6 2.9 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1351) AAA_13 PF13166.1 KLO05528.1 - 0.0022 16.5 4.6 0.0028 16.2 3.2 1.2 1 0 0 1 1 1 1 AAA domain FlxA PF14282.1 KLO05528.1 - 0.0064 16.4 11.0 0.02 14.8 7.0 2.0 1 1 1 2 2 2 1 FlxA-like protein TMF_TATA_bd PF12325.3 KLO05528.1 - 0.013 15.2 8.7 0.013 15.2 6.0 2.1 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding Transposase_22 PF02994.9 KLO05528.1 - 0.027 12.9 8.2 0.039 12.4 5.7 1.3 1 0 0 1 1 1 0 L1 transposable element Tektin PF03148.9 KLO05528.1 - 0.027 13.0 18.9 0.057 11.9 3.6 2.0 1 1 1 2 2 2 0 Tektin family MscS_porin PF12795.2 KLO05528.1 - 0.047 13.0 17.0 0.12 11.7 4.2 2.0 1 1 1 2 2 2 0 Mechanosensitive ion channel porin domain DUF812 PF05667.6 KLO05528.1 - 0.078 11.4 15.5 0.22 9.9 3.3 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF812) DUF948 PF06103.6 KLO05528.1 - 0.089 12.6 7.6 1.6 8.6 1.8 3.3 1 1 3 4 4 4 0 Bacterial protein of unknown function (DUF948) Mgr1 PF08602.5 KLO05528.1 - 0.092 11.7 2.0 0.11 11.4 1.4 1.1 1 0 0 1 1 1 0 Mgr1-like, i-AAA protease complex subunit COG5 PF10392.4 KLO05528.1 - 0.11 12.4 10.0 0.28 11.1 5.2 2.4 1 1 1 2 2 2 0 Golgi transport complex subunit 5 DivIC PF04977.10 KLO05528.1 - 0.14 11.6 10.9 1.1 8.7 1.3 3.1 1 1 2 3 3 3 0 Septum formation initiator TBPIP PF07106.8 KLO05528.1 - 0.15 11.5 8.8 0.24 10.9 6.0 1.5 1 1 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) CALCOCO1 PF07888.6 KLO05528.1 - 0.15 10.2 13.3 0.19 9.9 9.2 1.0 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like DUF2730 PF10805.3 KLO05528.1 - 0.18 11.5 8.9 0.077 12.7 1.6 2.8 1 1 2 3 3 3 0 Protein of unknown function (DUF2730) LOH1CR12 PF10158.4 KLO05528.1 - 0.19 11.4 3.5 0.31 10.8 1.6 1.8 1 1 1 2 2 2 0 Tumour suppressor protein PMC2NT PF08066.7 KLO05528.1 - 0.2 11.9 5.2 0.27 11.5 1.7 2.2 2 0 0 2 2 2 0 PMC2NT (NUC016) domain DUF3584 PF12128.3 KLO05528.1 - 0.21 8.8 13.0 0.29 8.4 9.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) ADIP PF11559.3 KLO05528.1 - 0.21 11.4 18.4 0.92 9.4 1.2 2.6 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding ALMT PF11744.3 KLO05528.1 - 0.23 10.0 2.2 0.24 10.0 1.5 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter Laminin_II PF06009.7 KLO05528.1 - 0.25 11.0 6.5 0.46 10.2 2.6 1.9 1 1 1 2 2 2 0 Laminin Domain II Med9 PF07544.8 KLO05528.1 - 0.28 10.9 6.8 0.85 9.4 4.7 1.8 1 1 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 TPR_MLP1_2 PF07926.7 KLO05528.1 - 0.3 10.8 12.8 1.4 8.6 8.9 2.0 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein Ax_dynein_light PF10211.4 KLO05528.1 - 0.4 10.4 12.8 1.3 8.8 1.5 2.3 1 1 2 3 3 3 0 Axonemal dynein light chain SseC PF04888.7 KLO05528.1 - 0.4 9.9 4.5 0.51 9.6 3.1 1.1 1 0 0 1 1 1 0 Secretion system effector C (SseC) like family TPK_catalytic PF04263.11 KLO05528.1 - 0.42 10.1 2.8 0.42 10.2 0.7 1.9 2 1 0 2 2 1 0 Thiamin pyrophosphokinase, catalytic domain CLP_protease PF00574.18 KLO05528.1 - 0.42 10.2 3.8 7.7 6.1 0.2 2.2 1 1 1 2 2 2 0 Clp protease V_ATPase_I PF01496.14 KLO05528.1 - 0.47 8.2 7.0 0.6 7.9 4.9 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Flagellin_N PF00669.15 KLO05528.1 - 0.51 10.1 6.6 0.1 12.4 0.9 2.1 2 1 0 2 2 2 0 Bacterial flagellin N-terminal helical region Mnd1 PF03962.10 KLO05528.1 - 0.54 9.8 14.3 0.27 10.8 3.5 2.0 1 1 1 2 2 2 0 Mnd1 family Pup PF05639.6 KLO05528.1 - 0.55 10.7 9.3 0.31 11.5 2.6 2.6 2 1 1 3 3 2 0 Pup-like protein DUF342 PF03961.8 KLO05528.1 - 0.63 8.3 5.8 0.8 8.0 4.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF342) BRE1 PF08647.6 KLO05528.1 - 0.65 10.0 12.9 2.6 8.0 6.5 2.2 1 1 0 2 2 2 0 BRE1 E3 ubiquitin ligase Ran-binding PF05508.6 KLO05528.1 - 0.77 8.5 5.4 0.53 9.1 2.6 1.5 1 1 0 2 2 2 0 RanGTP-binding protein DivIVA PF05103.8 KLO05528.1 - 0.81 9.7 10.6 2.8 8.0 7.2 2.1 1 1 0 1 1 1 0 DivIVA protein zf-C4H2 PF10146.4 KLO05528.1 - 0.82 9.6 11.0 0.69 9.8 6.6 1.5 1 1 0 1 1 1 0 Zinc finger-containing protein SlyX PF04102.7 KLO05528.1 - 0.89 9.9 11.3 8.4 6.8 1.9 3.6 1 1 2 3 3 3 0 SlyX ORF6C PF10552.4 KLO05528.1 - 0.9 9.2 6.4 8.6 6.1 2.7 2.9 2 1 1 3 3 3 0 ORF6C domain Filament PF00038.16 KLO05528.1 - 0.97 8.8 15.5 0.19 11.1 3.7 2.1 1 1 1 2 2 2 0 Intermediate filament protein HrpB7 PF09486.5 KLO05528.1 - 1 9.2 17.6 1.7 8.5 1.7 2.5 1 1 2 3 3 3 0 Bacterial type III secretion protein (HrpB7) Atg14 PF10186.4 KLO05528.1 - 1.1 8.0 15.1 1.7 7.5 10.1 1.5 1 1 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DUF972 PF06156.8 KLO05528.1 - 1.2 9.5 8.3 37 4.7 5.8 2.5 1 1 0 1 1 1 0 Protein of unknown function (DUF972) GrpE PF01025.14 KLO05528.1 - 1.2 8.6 11.6 0.19 11.2 3.2 2.3 1 1 1 2 2 2 0 GrpE TMF_DNA_bd PF12329.3 KLO05528.1 - 1.2 8.9 12.4 10 6.0 0.1 3.0 1 1 2 3 3 3 0 TATA element modulatory factor 1 DNA binding TSC22 PF01166.13 KLO05528.1 - 1.3 9.0 6.5 1.9 8.5 1.1 2.8 2 1 1 3 3 2 0 TSC-22/dip/bun family Prominin PF05478.6 KLO05528.1 - 1.5 6.2 5.9 1.6 6.1 4.1 1.1 1 0 0 1 1 1 0 Prominin Fib_alpha PF08702.5 KLO05528.1 - 1.5 8.8 11.6 0.71 9.9 5.3 1.9 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Bacillus_HBL PF05791.6 KLO05528.1 - 1.6 8.0 6.2 1.7 7.9 3.5 1.6 1 1 1 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) EzrA PF06160.7 KLO05528.1 - 1.6 6.8 12.4 3.1 5.8 8.5 1.5 1 1 0 1 1 1 0 Septation ring formation regulator, EzrA DUF4407 PF14362.1 KLO05528.1 - 1.8 7.4 9.1 2.4 7.0 6.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) APG6 PF04111.7 KLO05528.1 - 1.9 7.4 14.0 1.3 7.9 7.4 1.7 1 1 0 1 1 1 0 Autophagy protein Apg6 Sec2p PF06428.6 KLO05528.1 - 2 8.3 11.6 3.7 7.4 4.3 2.8 1 1 0 2 2 2 0 GDP/GTP exchange factor Sec2p DUF4140 PF13600.1 KLO05528.1 - 2.4 8.6 13.9 4.4 7.8 1.5 3.2 1 1 2 3 3 3 0 N-terminal domain of unknown function (DUF4140) Spectrin PF00435.16 KLO05528.1 - 2.4 8.4 11.3 3.7 7.8 6.5 2.0 1 1 1 2 2 2 0 Spectrin repeat Tmemb_cc2 PF10267.4 KLO05528.1 - 2.4 6.6 12.5 0.45 9.0 3.8 2.0 1 1 1 2 2 2 0 Predicted transmembrane and coiled-coil 2 protein bZIP_1 PF00170.16 KLO05528.1 - 2.8 7.9 14.4 5.7 6.9 1.3 2.7 1 1 0 2 2 2 0 bZIP transcription factor ATG16 PF08614.6 KLO05528.1 - 2.8 7.7 17.3 2.4 7.9 3.9 2.1 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) MbeD_MobD PF04899.7 KLO05528.1 - 2.9 7.8 7.5 7.1 6.6 1.2 3.0 2 1 1 3 3 3 0 MbeD/MobD like DUF3373 PF11853.3 KLO05528.1 - 3 6.2 8.0 5.3 5.4 5.5 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3373) Syntaxin-6_N PF09177.6 KLO05528.1 - 3.2 8.2 10.7 73 3.8 6.7 2.5 1 1 1 2 2 2 0 Syntaxin 6, N-terminal DUF4200 PF13863.1 KLO05528.1 - 3.3 7.6 16.3 8 6.4 3.5 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) IncA PF04156.9 KLO05528.1 - 3.4 7.2 16.0 32 4.0 11.0 2.3 1 1 0 1 1 1 0 IncA protein Prefoldin_2 PF01920.15 KLO05528.1 - 3.5 7.4 12.3 1.8 8.3 2.1 3.1 1 1 1 3 3 3 0 Prefoldin subunit DUF2011 PF09428.5 KLO05528.1 - 4.6 7.1 7.2 7.4 6.4 5.0 1.4 1 1 0 1 1 1 0 Fungal protein of unknown function (DUF2011) DUF2203 PF09969.4 KLO05528.1 - 6.1 7.0 7.5 5.5 7.2 2.7 2.0 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) BLOC1_2 PF10046.4 KLO05528.1 - 6.8 6.8 9.0 28 4.9 4.8 2.5 2 1 0 2 2 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 TMPIT PF07851.8 KLO05528.1 - 7 5.6 7.5 6.1 5.8 4.4 1.4 1 1 1 2 2 2 0 TMPIT-like protein FUSC PF04632.7 KLO05528.1 - 7.2 4.9 7.7 11 4.2 5.3 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family Wbp11 PF09429.5 KLO05528.1 - 7.3 6.6 11.8 0.76 9.7 1.8 2.8 1 1 2 3 3 3 0 WW domain binding protein 11 ATP-synt_B PF00430.13 KLO05528.1 - 7.9 6.2 10.7 2.8 7.7 5.0 1.9 1 1 0 1 1 1 0 ATP synthase B/B' CF(0) Bap31 PF05529.7 KLO05528.1 - 8.6 5.7 8.1 32 3.8 5.6 2.0 1 1 0 1 1 1 0 B-cell receptor-associated protein 31-like Rho_Binding PF08912.6 KLO05528.1 - 9 6.6 8.8 1.4 9.3 2.7 2.2 2 1 1 3 3 1 0 Rho Binding Vfa1 PF08432.5 KLO05528.1 - 9.1 6.2 8.9 13 5.7 6.1 1.2 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Adeno_PIX PF03955.9 KLO05528.1 - 9.6 6.7 7.1 5.7 7.5 1.8 2.2 1 1 0 2 2 2 0 Adenovirus hexon-associated protein (IX) DUF4404 PF14357.1 KLO05529.1 - 0.094 13.1 1.9 0.14 12.5 1.3 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4404) MoaF PF10703.4 KLO05529.1 - 0.14 11.1 0.1 0.15 11.0 0.1 1.0 1 0 0 1 1 1 0 Molybdenum cofactor biosynthesis protein F DUF3038 PF11237.3 KLO05529.1 - 0.16 11.7 3.7 0.19 11.5 2.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3038) PucR PF07905.6 KLO05531.1 - 0.13 11.8 0.0 0.28 10.7 0.0 1.5 1 0 0 1 1 1 0 Purine catabolism regulatory protein-like family Ribosomal_L5_C PF00673.16 KLO05532.1 - 6.2e-16 57.9 0.0 1.9e-15 56.3 0.0 1.8 1 1 0 1 1 1 1 ribosomal L5P family C-terminus DUF4436 PF14494.1 KLO05534.1 - 0.00043 19.6 0.5 0.0032 16.8 0.3 2.0 1 1 0 1 1 1 1 Domain of unknown function (DUF4436) DUF2910 PF11139.3 KLO05534.1 - 0.002 17.2 7.9 0.003 16.7 2.8 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF2910) FAD_binding_4 PF01565.18 KLO05539.1 - 1.2e-17 63.6 0.2 2.8e-17 62.4 0.2 1.6 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 KLO05539.1 - 4e-07 29.8 0.0 8.6e-07 28.7 0.0 1.6 1 0 0 1 1 1 1 Berberine and berberine like Peptidase_M64 PF09471.5 KLO05540.1 - 2.7e-25 89.5 0.0 3.8e-25 89.0 0.0 1.2 1 0 0 1 1 1 1 IgA Peptidase M64 MRP-L47 PF06984.8 KLO05541.1 - 8.7e-21 73.6 0.8 1.9e-20 72.5 0.5 1.6 1 0 0 1 1 1 1 Mitochondrial 39-S ribosomal protein L47 (MRP-L47) MscS_TM PF12794.2 KLO05541.1 - 0.81 8.2 6.1 0.16 10.5 0.8 2.1 2 0 0 2 2 2 0 Mechanosensitive ion channel inner membrane domain 1 Complex1_LYR PF05347.10 KLO05542.1 - 0.0025 17.5 0.4 0.0031 17.2 0.3 1.2 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 KLO05542.1 - 0.0039 17.3 0.3 0.0046 17.1 0.2 1.1 1 0 0 1 1 1 1 Complex1_LYR-like Pkinase PF00069.20 KLO05545.1 - 4.3e-11 42.4 0.0 4.7e-11 42.3 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KLO05545.1 - 1.3e-05 24.4 0.0 1.5e-05 24.1 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 KLO05545.1 - 0.0013 17.8 0.0 0.0013 17.8 0.0 1.1 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KLO05545.1 - 0.006 16.3 0.0 0.0083 15.8 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.4 KLO05545.1 - 0.14 11.5 0.0 0.18 11.1 0.0 1.2 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL TraU PF06834.6 KLO05547.1 - 0.086 11.9 0.1 0.12 11.5 0.1 1.1 1 0 0 1 1 1 0 TraU protein PPR_2 PF13041.1 KLO05547.1 - 0.14 12.1 0.0 24 5.0 0.0 2.4 2 0 0 2 2 2 0 PPR repeat family F-box-like PF12937.2 KLO05550.1 - 4.8e-09 35.7 2.9 7.4e-09 35.2 0.9 2.3 2 1 0 2 2 2 1 F-box-like F-box PF00646.28 KLO05550.1 - 0.62 9.7 4.8 4.7 6.9 0.2 3.1 3 0 0 3 3 3 0 F-box domain PDGLE PF13190.1 KLO05554.1 - 0.31 10.7 2.7 0.17 11.5 0.3 1.7 2 0 0 2 2 2 0 PDGLE domain SRCR PF00530.13 KLO05559.1 - 0.15 12.3 0.0 0.33 11.3 0.0 1.5 1 0 0 1 1 1 0 Scavenger receptor cysteine-rich domain NDUFA12 PF05071.11 KLO05562.1 - 0.2 12.1 4.9 0.26 11.7 0.0 3.0 3 0 0 3 3 3 0 NADH ubiquinone oxidoreductase subunit NDUFA12 KOW PF00467.24 KLO05564.1 - 1.2e-11 43.8 12.0 0.012 15.3 0.0 6.5 6 0 0 6 6 6 5 KOW motif Spt5-NGN PF03439.8 KLO05564.1 - 0.044 13.5 0.0 0.087 12.5 0.0 1.5 1 0 0 1 1 1 0 Early transcription elongation factor of RNA pol II, NGN section Pox_ser-thr_kin PF05445.6 KLO05564.1 - 0.11 11.2 0.0 0.17 10.6 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase zf-B_box PF00643.19 KLO05566.1 - 0.12 12.2 4.6 0.32 10.9 3.2 1.7 1 0 0 1 1 1 0 B-box zinc finger MMS19_N PF14500.1 KLO05567.1 - 0.16 11.2 0.0 3.1 6.9 0.0 2.1 2 0 0 2 2 2 0 Dos2-interacting transcription regulator of RNA-Pol-II zf-MYND PF01753.13 KLO05568.1 - 4e-06 26.5 17.2 1.2e-05 25.0 12.0 1.9 1 0 0 1 1 1 1 MYND finger WHH PF14414.1 KLO05568.1 - 0.11 11.7 0.0 0.21 10.8 0.0 1.5 1 0 0 1 1 1 0 A nuclease of the HNH/ENDO VII superfamily with conserved WHH cobW PF02492.14 KLO05569.1 - 0.086 12.2 0.1 0.34 10.3 0.0 1.8 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Orbi_VP5 PF00901.12 KLO05569.1 - 0.1 10.7 0.1 0.11 10.7 0.0 1.0 1 0 0 1 1 1 0 Orbivirus outer capsid protein VP5 HTH_Tnp_Tc5 PF03221.11 KLO05570.1 - 3.2e-13 49.2 0.0 9.3e-13 47.7 0.0 1.9 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain CENP-B_N PF04218.8 KLO05570.1 - 2e-05 23.9 0.7 4.2e-05 22.8 0.5 1.5 1 0 0 1 1 1 1 CENP-B N-terminal DNA-binding domain HTH_3 PF01381.17 KLO05570.1 - 0.0011 18.7 0.1 0.0033 17.2 0.1 1.8 2 0 0 2 2 2 1 Helix-turn-helix F-box-like PF12937.2 KLO05570.1 - 0.0037 16.9 0.1 0.0095 15.6 0.1 1.7 1 0 0 1 1 1 1 F-box-like HTH_Tnp_4 PF13613.1 KLO05570.1 - 0.0053 16.2 0.0 0.02 14.4 0.0 2.0 2 0 0 2 2 2 1 Helix-turn-helix of DDE superfamily endonuclease HTH_psq PF05225.11 KLO05570.1 - 0.0082 15.6 0.0 0.22 11.1 0.0 2.6 2 0 0 2 2 2 1 helix-turn-helix, Psq domain HTH_38 PF13936.1 KLO05570.1 - 0.018 14.6 0.3 0.082 12.4 0.1 2.1 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_26 PF13443.1 KLO05570.1 - 0.022 14.9 0.0 0.058 13.5 0.0 1.7 1 0 0 1 1 1 0 Cro/C1-type HTH DNA-binding domain HTH_23 PF13384.1 KLO05570.1 - 0.023 14.3 0.1 0.083 12.5 0.0 2.0 2 0 0 2 2 2 0 Homeodomain-like domain HTH_28 PF13518.1 KLO05570.1 - 0.036 14.0 0.0 0.16 11.9 0.0 2.2 2 0 0 2 2 2 0 Helix-turn-helix domain MarR PF01047.17 KLO05570.1 - 0.044 13.4 0.0 0.17 11.6 0.0 2.0 1 0 0 1 1 1 0 MarR family HTH_19 PF12844.2 KLO05570.1 - 0.049 13.6 0.0 0.16 12.0 0.0 1.9 2 0 0 2 2 2 0 Helix-turn-helix domain MarR_2 PF12802.2 KLO05570.1 - 0.05 13.2 0.0 0.17 11.6 0.0 1.9 1 0 0 1 1 1 0 MarR family HTH_Crp_2 PF13545.1 KLO05570.1 - 0.065 13.0 0.0 0.25 11.1 0.0 2.0 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain HTH_31 PF13560.1 KLO05570.1 - 0.066 13.4 0.6 0.6 10.3 0.4 2.6 1 1 0 1 1 1 0 Helix-turn-helix domain Hen1_L PF12623.2 KLO05570.1 - 0.076 11.7 0.2 0.16 10.7 0.0 1.6 2 0 0 2 2 2 0 RNA repair, ligase-Pnkp-associating, region of Hen1 Skp1 PF01466.14 KLO05571.1 - 2.5e-20 72.2 0.0 3.8e-20 71.6 0.0 1.3 1 0 0 1 1 1 1 Skp1 family, dimerisation domain Skp1_POZ PF03931.10 KLO05571.1 - 1.7e-11 44.0 0.0 2.6e-11 43.4 0.0 1.3 1 0 0 1 1 1 1 Skp1 family, tetramerisation domain L31 PF09784.4 KLO05573.1 - 0.053 13.5 0.1 0.4 10.7 0.0 2.0 2 0 0 2 2 2 0 Mitochondrial ribosomal protein L31 S-antigen PF05756.6 KLO05573.1 - 0.48 10.4 3.6 2.5 8.1 0.0 2.4 2 0 0 2 2 2 0 S-antigen protein Lys PF00062.15 KLO05574.1 - 0.043 13.7 0.1 0.064 13.2 0.0 1.2 1 0 0 1 1 1 0 C-type lysozyme/alpha-lactalbumin family Sec7_N PF12783.2 KLO05577.1 - 0.015 14.7 0.0 0.024 14.0 0.0 1.3 1 1 0 1 1 1 0 Guanine nucleotide exchange factor in Golgi transport N-terminal TPR_12 PF13424.1 KLO05578.1 - 9.6e-26 89.5 14.1 6.3e-09 35.6 0.1 5.7 3 2 1 5 5 5 5 Tetratricopeptide repeat TPR_10 PF13374.1 KLO05578.1 - 6.9e-23 79.8 15.9 0.0015 18.3 0.0 8.1 8 0 0 8 8 8 7 Tetratricopeptide repeat Apc5 PF12862.2 KLO05578.1 - 1.4e-12 47.2 19.5 0.29 11.0 0.2 8.4 1 1 7 8 8 8 4 Anaphase-promoting complex subunit 5 AAA_16 PF13191.1 KLO05578.1 - 7.3e-09 35.8 0.5 3.5e-08 33.6 0.0 2.5 2 1 0 2 2 2 1 AAA ATPase domain TPR_11 PF13414.1 KLO05578.1 - 5.9e-08 32.2 14.0 0.0027 17.2 0.1 5.4 2 1 4 6 6 6 4 TPR repeat TPR_8 PF13181.1 KLO05578.1 - 1.6e-06 27.4 0.1 2.6 8.0 0.0 6.1 7 0 0 7 7 7 1 Tetratricopeptide repeat AAA_19 PF13245.1 KLO05578.1 - 2.2e-06 27.2 0.0 1.5e-05 24.6 0.0 2.5 2 0 0 2 2 2 1 Part of AAA domain TPR_2 PF07719.12 KLO05578.1 - 7.2e-06 25.5 0.0 39 4.5 0.0 7.1 8 0 0 8 8 6 0 Tetratricopeptide repeat NACHT PF05729.7 KLO05578.1 - 2.1e-05 24.2 0.0 4.7e-05 23.1 0.0 1.6 1 0 0 1 1 1 1 NACHT domain DUF3856 PF12968.2 KLO05578.1 - 0.00093 19.0 13.2 0.051 13.3 0.6 3.7 1 1 1 3 3 3 1 Domain of Unknown Function (DUF3856) AAA PF00004.24 KLO05578.1 - 0.0012 19.0 0.0 0.004 17.3 0.0 2.0 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) NTPase_1 PF03266.10 KLO05578.1 - 0.0014 18.3 0.0 0.0076 15.9 0.0 2.1 2 0 0 2 2 2 1 NTPase AAA_18 PF13238.1 KLO05578.1 - 0.0018 18.5 0.0 0.0094 16.2 0.0 2.2 2 0 0 2 2 1 1 AAA domain AAA_17 PF13207.1 KLO05578.1 - 0.0049 17.6 0.0 0.014 16.2 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 KLO05578.1 - 0.0056 16.8 0.0 0.056 13.5 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.1 KLO05578.1 - 0.0067 16.4 0.5 0.03 14.2 0.1 2.2 2 0 0 2 2 2 1 AAA domain TPR_1 PF00515.23 KLO05578.1 - 0.0071 15.9 0.1 20 4.9 0.0 5.2 8 0 0 8 8 6 0 Tetratricopeptide repeat AAA_30 PF13604.1 KLO05578.1 - 0.0078 15.8 0.2 0.025 14.1 0.1 1.9 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.9 KLO05578.1 - 0.01 15.5 0.0 0.034 13.8 0.0 1.9 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_25 PF13481.1 KLO05578.1 - 0.029 13.7 0.0 0.11 11.9 0.0 1.9 1 0 0 1 1 1 0 AAA domain GAS PF13851.1 KLO05578.1 - 0.08 12.1 1.0 0.72 9.0 0.1 2.5 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding KTI12 PF08433.5 KLO05578.1 - 0.12 11.5 0.0 0.86 8.7 0.0 2.2 2 0 0 2 2 2 0 Chromatin associated protein KTI12 AAA_23 PF13476.1 KLO05578.1 - 0.17 12.1 0.1 0.48 10.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain dCMP_cyt_deam_2 PF08211.6 KLO05578.1 - 0.99 9.4 7.8 62 3.6 0.0 5.7 2 1 5 7 7 6 0 Cytidine and deoxycytidylate deaminase zinc-binding region TPR_17 PF13431.1 KLO05578.1 - 1 9.7 4.8 81 3.7 0.0 4.7 5 0 0 5 5 3 0 Tetratricopeptide repeat FtsA PF14450.1 KLO05578.1 - 1.7 8.4 5.6 0.33 10.7 0.3 2.5 3 1 0 3 3 2 0 Cell division protein FtsA DUF2783 PF10932.3 KLO05578.1 - 3.2 7.3 14.9 1.9 8.0 0.1 5.4 3 1 2 5 5 5 0 Protein of unknown function (DUF2783) zf-CCHC_3 PF13917.1 KLO05579.1 - 1e-21 76.3 2.5 1.6e-21 75.7 1.7 1.3 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.1 KLO05579.1 - 0.06 12.8 0.4 0.06 12.8 0.3 1.8 2 0 0 2 2 2 0 Zinc knuckle zf-CCHC PF00098.18 KLO05579.1 - 0.34 10.9 2.3 0.69 9.9 1.6 1.6 1 0 0 1 1 1 0 Zinc knuckle HATPase_c PF02518.21 KLO05580.1 - 2.7e-24 85.0 0.0 6e-24 83.8 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 KLO05580.1 - 3e-16 59.4 0.1 5.8e-15 55.2 0.0 2.5 1 1 0 1 1 1 1 Response regulator receiver domain GAF PF01590.21 KLO05580.1 - 2.5e-14 53.6 0.0 5.4e-14 52.5 0.0 1.6 1 0 0 1 1 1 1 GAF domain PHY PF00360.15 KLO05580.1 - 7.5e-12 44.7 0.0 1.3e-11 43.9 0.0 1.3 1 0 0 1 1 1 1 Phytochrome region PAS_2 PF08446.6 KLO05580.1 - 1.5e-09 38.2 0.0 3.8e-09 36.9 0.0 1.7 1 0 0 1 1 1 1 PAS fold HisKA PF00512.20 KLO05580.1 - 1.3e-08 34.7 1.0 3.5e-08 33.3 0.7 1.7 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain OKR_DC_1_N PF03709.10 KLO05580.1 - 0.19 11.7 0.0 0.51 10.4 0.0 1.7 1 0 0 1 1 1 0 Orn/Lys/Arg decarboxylase, N-terminal domain DUF1762 PF08574.5 KLO05581.1 - 1.6e-09 38.0 11.0 1.6e-09 38.0 7.6 2.7 1 1 1 2 2 2 1 Protein of unknown function (DUF1762) Adaptin_binding PF10199.4 KLO05581.1 - 3.4 7.9 8.3 5.3 7.3 0.0 2.5 2 1 0 2 2 2 0 Alpha and gamma adaptin binding protein p34 Abhydrolase_5 PF12695.2 KLO05582.1 - 8.6e-17 61.2 0.0 1.9e-16 60.1 0.0 1.5 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KLO05582.1 - 6e-14 52.4 1.5 2.2e-13 50.6 0.9 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.8 KLO05582.1 - 2e-09 37.3 0.2 3.4e-09 36.6 0.1 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_1 PF00561.15 KLO05582.1 - 0.00032 20.3 0.1 0.0017 17.9 0.1 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.3 KLO05582.1 - 0.0018 18.0 0.0 0.007 16.1 0.0 1.9 2 0 0 2 2 2 1 Putative lysophospholipase Peptidase_S15 PF02129.13 KLO05582.1 - 0.0084 15.5 0.0 0.016 14.6 0.0 1.4 2 0 0 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) DUF818 PF05677.7 KLO05582.1 - 0.016 13.9 0.0 0.023 13.4 0.0 1.1 1 0 0 1 1 1 0 Chlamydia CHLPS protein (DUF818) Peptidase_S28 PF05577.7 KLO05582.1 - 0.02 13.5 0.0 0.027 13.0 0.0 1.1 1 0 0 1 1 1 0 Serine carboxypeptidase S28 Ytp1 PF10355.4 KLO05583.1 - 4.7e-72 242.4 13.1 4.7e-72 242.4 9.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (Ytp1) DUF2427 PF10348.4 KLO05583.1 - 3.7e-24 84.3 3.2 3.7e-24 84.3 2.2 3.1 4 0 0 4 4 4 2 Domain of unknown function (DUF2427) Cytochrom_B561 PF03188.11 KLO05583.1 - 0.0034 17.2 5.0 0.0034 17.2 3.4 4.2 3 2 1 4 4 4 2 Eukaryotic cytochrome b561 GIDE PF12483.3 KLO05587.1 - 0.097 12.0 0.0 0.13 11.5 0.0 1.2 1 0 0 1 1 1 0 E3 Ubiquitin ligase DUF3176 PF11374.3 KLO05590.1 - 0.11 12.4 1.7 0.19 11.6 0.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3176) MULE PF10551.4 KLO05591.1 - 8e-10 38.7 0.0 1.7e-09 37.6 0.0 1.6 1 0 0 1 1 1 1 MULE transposase domain HTH_13 PF11972.3 KLO05592.1 - 0.062 13.1 0.2 0.13 12.1 0.1 1.5 1 0 0 1 1 1 0 HTH DNA binding domain Copper-bind PF00127.15 KLO05596.1 - 0.0018 18.4 0.0 0.0042 17.3 0.0 1.6 1 1 0 1 1 1 1 Copper binding proteins, plastocyanin/azurin family LIF_OSM PF01291.12 KLO05598.1 - 0.019 14.9 0.2 0.47 10.3 0.1 2.4 2 0 0 2 2 2 0 LIF / OSM family ERM PF00769.14 KLO05601.1 - 6.9e-06 25.7 3.7 6.9e-06 25.7 2.6 2.0 2 0 0 2 2 2 1 Ezrin/radixin/moesin family Atg14 PF10186.4 KLO05601.1 - 0.0014 17.6 9.3 0.0022 16.9 6.5 1.2 1 0 0 1 1 1 1 UV radiation resistance protein and autophagy-related subunit 14 Filament PF00038.16 KLO05601.1 - 0.002 17.6 11.0 0.0031 17.0 7.6 1.2 1 0 0 1 1 1 1 Intermediate filament protein CENP-F_leu_zip PF10473.4 KLO05601.1 - 0.0022 17.8 15.5 0.024 14.4 2.6 2.4 1 1 1 2 2 2 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 TPR_MLP1_2 PF07926.7 KLO05601.1 - 0.0024 17.6 15.3 0.12 12.1 5.8 2.5 1 1 1 2 2 2 2 TPR/MLP1/MLP2-like protein FliJ PF02050.11 KLO05601.1 - 0.0041 17.1 9.2 0.0092 16.0 6.4 1.6 1 0 0 1 1 1 1 Flagellar FliJ protein DUF812 PF05667.6 KLO05601.1 - 0.0042 15.6 10.4 0.0082 14.7 7.2 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF812) Cast PF10174.4 KLO05601.1 - 0.0052 14.9 16.7 0.011 13.8 11.5 1.4 1 0 0 1 1 1 1 RIM-binding protein of the cytomatrix active zone IncA PF04156.9 KLO05601.1 - 0.0073 15.9 7.6 0.0073 15.9 5.2 2.3 1 1 1 2 2 2 1 IncA protein Laminin_II PF06009.7 KLO05601.1 - 0.0085 15.8 1.8 0.0085 15.8 1.2 2.3 1 1 1 2 2 2 1 Laminin Domain II Tropomyosin_1 PF12718.2 KLO05601.1 - 0.01 15.6 14.6 0.021 14.6 10.1 1.5 1 0 0 1 1 1 0 Tropomyosin like AAA_13 PF13166.1 KLO05601.1 - 0.011 14.2 9.0 0.038 12.4 6.4 1.5 1 1 0 1 1 1 0 AAA domain DUF3584 PF12128.3 KLO05601.1 - 0.013 12.8 13.0 0.018 12.4 9.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) V_ATPase_I PF01496.14 KLO05601.1 - 0.024 12.5 4.3 0.032 12.1 3.0 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family TMF_DNA_bd PF12329.3 KLO05601.1 - 0.04 13.7 12.9 0.055 13.2 0.5 3.4 2 1 1 3 3 3 0 TATA element modulatory factor 1 DNA binding Reo_sigmaC PF04582.7 KLO05601.1 - 0.07 12.3 3.8 0.61 9.2 1.4 2.0 1 1 0 1 1 1 0 Reovirus sigma C capsid protein ADIP PF11559.3 KLO05601.1 - 0.084 12.7 15.8 1.1 9.1 1.6 2.4 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding DUF1241 PF06840.6 KLO05601.1 - 0.15 11.2 2.7 0.31 10.2 1.9 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1241) Matrilin_ccoil PF10393.4 KLO05601.1 - 0.18 11.1 0.4 3.6 7.0 0.0 2.3 2 0 0 2 2 2 0 Trimeric coiled-coil oligomerisation domain of matrilin Tropomyosin PF00261.15 KLO05601.1 - 0.18 10.8 15.1 0.38 9.8 9.8 1.8 1 1 0 1 1 1 0 Tropomyosin DUF972 PF06156.8 KLO05601.1 - 0.25 11.7 9.5 0.15 12.4 1.2 2.9 1 1 1 2 2 2 0 Protein of unknown function (DUF972) APG6 PF04111.7 KLO05601.1 - 0.3 10.1 15.5 1.8 7.5 3.9 2.4 1 1 1 2 2 2 0 Autophagy protein Apg6 Phage_GP20 PF06810.6 KLO05601.1 - 0.35 10.2 15.3 2 7.8 2.7 2.5 1 1 1 2 2 2 0 Phage minor structural protein GP20 Cas_Csa4 PF09703.5 KLO05601.1 - 0.4 9.6 2.2 0.67 8.8 1.5 1.3 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Csa4) CENP-Q PF13094.1 KLO05601.1 - 0.42 10.6 17.6 0.25 11.3 3.6 2.7 1 1 2 3 3 3 0 CENP-Q, a CENPA-CAD centromere complex subunit DUF948 PF06103.6 KLO05601.1 - 0.53 10.1 5.4 1.8 8.4 0.5 2.6 1 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) GAS PF13851.1 KLO05601.1 - 0.55 9.4 15.5 1.1 8.4 1.6 2.2 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding DUF4349 PF14257.1 KLO05601.1 - 0.59 9.3 10.6 1.5 7.9 7.3 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4349) DUF4407 PF14362.1 KLO05601.1 - 0.63 8.9 6.1 1 8.2 4.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF342 PF03961.8 KLO05601.1 - 1.3 7.3 8.2 18 3.5 0.1 2.3 2 1 1 3 3 3 0 Protein of unknown function (DUF342) CENP-K PF11802.3 KLO05601.1 - 2.7 7.1 8.6 1.2 8.3 1.8 2.0 1 1 1 2 2 2 0 Centromere-associated protein K Spc7 PF08317.6 KLO05601.1 - 6.7 5.2 13.4 75 1.8 3.7 2.0 1 1 0 1 1 1 0 Spc7 kinetochore protein WD40 PF00400.27 KLO05602.1 - 5.8e-10 38.6 14.7 2.5e-07 30.3 0.1 6.0 6 1 1 7 7 7 3 WD domain, G-beta repeat DUF4218 PF13960.1 KLO05603.1 - 0.0044 16.4 0.0 0.0085 15.5 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4218) BAF1_ABF1 PF04684.8 KLO05604.1 - 0.024 13.5 0.1 0.032 13.1 0.0 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Lectin_N PF03954.9 KLO05606.1 - 0.44 9.9 3.3 34 3.8 0.0 3.3 3 0 0 3 3 3 0 Hepatic lectin, N-terminal domain FlaC_arch PF05377.6 KLO05606.1 - 0.44 10.4 3.2 12 5.8 0.2 3.3 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) FUSC PF04632.7 KLO05606.1 - 3.7 5.8 10.1 0.79 8.0 2.8 2.0 2 0 0 2 2 2 0 Fusaric acid resistance protein family PV-1 PF06637.6 KLO05606.1 - 9.9 4.6 14.0 5.2 5.5 7.5 2.0 2 0 0 2 2 2 0 PV-1 protein (PLVAP) Trehalase PF01204.13 KLO05608.1 - 9.8e-168 558.9 0.1 1.2e-167 558.6 0.1 1.1 1 0 0 1 1 1 1 Trehalase Trehalase_Ca-bi PF07492.6 KLO05608.1 - 7.8e-13 47.4 0.1 1.4e-12 46.6 0.1 1.4 1 0 0 1 1 1 1 Neutral trehalase Ca2+ binding domain Bundlin PF05307.6 KLO05608.1 - 0.13 12.1 0.1 0.3 10.9 0.1 1.5 1 0 0 1 1 1 0 Bundlin DUF676 PF05057.9 KLO05609.1 - 3.8e-41 140.7 0.0 5.3e-41 140.3 0.0 1.2 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Lipase_3 PF01764.20 KLO05609.1 - 0.0052 16.3 0.0 0.01 15.4 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) RecQ5 PF06959.6 KLO05609.1 - 0.021 14.4 0.6 0.033 13.8 0.4 1.2 1 0 0 1 1 1 0 RecQ helicase protein-like 5 (RecQ5) Leu_zip PF15294.1 KLO05613.1 - 0.035 13.2 2.3 0.066 12.3 1.6 1.3 1 0 0 1 1 1 0 Leucine zipper RNA_pol_Rpb2_4 PF04566.8 KLO05613.1 - 0.058 13.2 1.5 1.7 8.5 0.0 2.9 2 1 0 2 2 2 0 RNA polymerase Rpb2, domain 4 DUF342 PF03961.8 KLO05613.1 - 0.26 9.6 4.4 0.085 11.2 0.9 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF342) DUF2951 PF11166.3 KLO05613.1 - 6 6.7 6.7 13 5.6 2.3 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF2951) WD40 PF00400.27 KLO05616.1 - 2.7e-103 334.5 57.5 1.1e-11 44.0 0.2 15.4 14 1 1 15 15 15 13 WD domain, G-beta repeat NACHT PF05729.7 KLO05616.1 - 4.3e-07 29.7 0.0 9.3e-07 28.6 0.0 1.5 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 KLO05616.1 - 3.8e-06 27.0 0.2 9e-06 25.7 0.1 1.6 1 0 0 1 1 1 1 AAA ATPase domain Nup160 PF11715.3 KLO05616.1 - 2.7e-05 22.5 8.1 0.17 9.9 0.0 5.6 2 2 1 5 5 5 2 Nucleoporin Nup120/160 AAA_17 PF13207.1 KLO05616.1 - 0.00019 22.2 0.0 0.00052 20.8 0.0 1.8 1 0 0 1 1 1 1 AAA domain DUF3312 PF11768.3 KLO05616.1 - 0.0011 17.2 0.3 1.4 7.0 0.1 4.3 3 2 1 4 4 4 1 Protein of unknown function (DUF3312) AAA_22 PF13401.1 KLO05616.1 - 0.0032 17.5 0.1 0.034 14.2 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA PF00004.24 KLO05616.1 - 0.0092 16.1 0.1 0.12 12.5 0.0 2.7 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) PhoH PF02562.11 KLO05616.1 - 0.013 14.6 0.0 0.03 13.5 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein KAP_NTPase PF07693.9 KLO05616.1 - 0.016 14.1 0.1 0.29 10.1 0.0 2.2 1 1 0 2 2 2 0 KAP family P-loop domain AAA_18 PF13238.1 KLO05616.1 - 0.018 15.3 0.0 0.042 14.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain APS_kinase PF01583.15 KLO05616.1 - 0.019 14.6 0.1 0.034 13.7 0.0 1.3 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA_19 PF13245.1 KLO05616.1 - 0.019 14.7 0.0 0.054 13.2 0.0 1.7 1 0 0 1 1 1 0 Part of AAA domain AAA_25 PF13481.1 KLO05616.1 - 0.019 14.3 0.0 0.052 12.9 0.0 1.8 1 0 0 1 1 1 0 AAA domain Arch_ATPase PF01637.13 KLO05616.1 - 0.025 14.2 0.0 0.18 11.4 0.0 2.2 2 0 0 2 2 2 0 Archaeal ATPase DUF2075 PF09848.4 KLO05616.1 - 0.027 13.4 0.0 0.042 12.8 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_33 PF13671.1 KLO05616.1 - 0.06 13.2 0.0 0.13 12.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.12 KLO05616.1 - 0.068 12.5 0.0 0.18 11.2 0.0 1.6 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_30 PF13604.1 KLO05616.1 - 0.13 11.7 0.3 0.38 10.3 0.0 1.8 2 0 0 2 2 2 0 AAA domain VP4_haemagglut PF00426.13 KLO05616.1 - 0.15 9.9 0.1 0.24 9.3 0.1 1.1 1 0 0 1 1 1 0 Outer Capsid protein VP4 (Hemagglutinin) DUF463 PF04317.7 KLO05616.1 - 0.29 9.6 0.0 0.47 8.9 0.0 1.2 1 0 0 1 1 1 0 YcjX-like family, DUF463 Alpha_GJ PF03229.8 KLO05617.1 - 0.02 15.2 2.6 0.026 14.8 0.6 2.1 2 0 0 2 2 2 0 Alphavirus glycoprotein J DUF4381 PF14316.1 KLO05617.1 - 0.042 13.9 0.2 0.084 12.9 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) FixQ PF05545.6 KLO05617.1 - 0.16 11.6 0.2 0.47 10.1 0.1 1.7 1 0 0 1 1 1 0 Cbb3-type cytochrome oxidase component FixQ MHYT PF03707.11 KLO05617.1 - 0.43 10.7 2.6 0.67 10.1 0.0 2.4 2 0 0 2 2 2 0 Bacterial signalling protein N terminal repeat adh_short PF00106.20 KLO05618.1 - 1.8e-32 112.5 0.4 2.6e-32 112.0 0.3 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KLO05618.1 - 2.3e-25 89.7 0.7 7.6e-25 88.0 0.5 1.7 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KLO05618.1 - 1.7e-17 63.7 0.2 2.5e-17 63.1 0.1 1.2 1 0 0 1 1 1 1 KR domain 3HCDH_N PF02737.13 KLO05618.1 - 0.022 14.4 0.7 0.037 13.6 0.5 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DUF881 PF05949.7 KLO05618.1 - 0.023 14.1 0.7 0.043 13.2 0.2 1.7 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF881) OPT PF03169.10 KLO05619.1 - 3.7e-198 659.9 59.7 4.2e-198 659.7 41.3 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein BCIP PF13862.1 KLO05621.1 - 2e-10 40.5 0.1 2.6e-10 40.1 0.1 1.1 1 0 0 1 1 1 1 p21-C-terminal region-binding protein Chorion_3 PF05387.6 KLO05621.1 - 0.07 12.5 0.0 0.07 12.5 0.0 1.0 1 0 0 1 1 1 0 Chorion family 3 GPI-anchored PF10342.4 KLO05623.1 - 2e-05 24.9 0.1 5.2e-05 23.6 0.1 1.6 1 1 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family DUF4448 PF14610.1 KLO05623.1 - 0.29 10.5 0.1 0.29 10.5 0.1 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF4448) GPI-anchored PF10342.4 KLO05625.1 - 0.012 16.0 4.2 0.06 13.8 2.9 2.0 1 1 0 1 1 1 0 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Avl9 PF09794.4 KLO05626.1 - 2e-128 428.1 0.0 2.7e-128 427.6 0.0 1.2 1 0 0 1 1 1 1 Transport protein Avl9 SPA PF08616.5 KLO05626.1 - 1.1e-10 41.2 0.2 0.00016 21.3 0.0 2.3 2 0 0 2 2 2 2 Stabilization of polarity axis DUF2347 PF09804.4 KLO05626.1 - 2.9e-08 33.3 1.0 0.00013 21.3 0.5 2.7 2 1 0 2 2 2 2 Uncharacterized conserved protein (DUF2347) TFIID_30kDa PF03540.8 KLO05626.1 - 0.023 14.4 0.0 0.049 13.4 0.0 1.5 1 0 0 1 1 1 0 Transcription initiation factor TFIID 23-30kDa subunit zf-DHHC PF01529.15 KLO05627.1 - 1.8e-35 121.9 7.4 1.8e-35 121.9 5.1 2.0 1 1 1 2 2 2 1 DHHC palmitoyltransferase DUF500 PF04366.7 KLO05628.1 - 5.3e-42 142.2 0.1 7.7e-42 141.7 0.1 1.2 1 0 0 1 1 1 1 Family of unknown function (DUF500) OpgC_C PF10129.4 KLO05630.1 - 0.018 13.7 0.0 0.021 13.5 0.0 1.1 1 0 0 1 1 1 0 OpgC protein zf-C2H2 PF00096.21 KLO05632.1 - 1.5e-07 31.3 8.6 0.017 15.4 0.3 3.6 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KLO05632.1 - 2.4e-07 30.6 8.6 0.18 12.1 0.8 3.6 3 0 0 3 3 3 3 C2H2-type zinc finger zf-H2C2_2 PF13465.1 KLO05632.1 - 0.0049 17.0 14.1 0.41 11.0 1.0 3.9 4 0 0 4 4 4 3 Zinc-finger double domain zf-met PF12874.2 KLO05632.1 - 0.051 13.7 1.0 25 5.2 0.0 3.3 3 0 0 3 3 3 0 Zinc-finger of C2H2 type IBR PF01485.16 KLO05632.1 - 0.52 10.2 3.6 3 7.7 0.2 2.3 2 0 0 2 2 2 0 IBR domain zf-C2H2_6 PF13912.1 KLO05632.1 - 0.67 9.9 3.2 21 5.2 0.9 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger zf-H2C2_5 PF13909.1 KLO05632.1 - 1.5 9.2 9.9 1.6 9.1 0.7 3.8 3 0 0 3 3 3 0 C2H2-type zinc-finger domain BUD22 PF09073.5 KLO05635.1 - 0.00092 18.3 15.4 0.00092 18.3 10.7 1.3 1 1 0 1 1 1 1 BUD22 Macoilin PF09726.4 KLO05635.1 - 0.053 11.8 9.5 0.062 11.5 6.6 1.1 1 0 0 1 1 1 0 Transmembrane protein DUF3306 PF11748.3 KLO05635.1 - 0.29 11.8 2.5 0.73 10.5 1.7 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3306) AUX_IAA PF02309.11 KLO05635.1 - 0.33 10.6 6.5 0.55 9.9 4.5 1.3 1 0 0 1 1 1 0 AUX/IAA family SR-25 PF10500.4 KLO05635.1 - 0.65 9.4 24.3 0.13 11.6 14.7 1.5 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein DUF566 PF04484.7 KLO05635.1 - 2.8 7.3 11.6 3.6 7.0 8.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF566) DUF4614 PF15391.1 KLO05635.1 - 3.8 7.2 11.9 5.8 6.6 8.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4614) Apt1 PF10351.4 KLO05635.1 - 3.8 6.2 8.5 4.3 6.0 5.9 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain FLO_LFY PF01698.11 KLO05635.1 - 4.4 6.0 8.0 6 5.5 5.6 1.2 1 0 0 1 1 1 0 Floricaula / Leafy protein Sec10 PF07393.6 KLO05635.1 - 7 4.6 6.1 7.8 4.5 4.2 1.1 1 0 0 1 1 1 0 Exocyst complex component Sec10 Dsh_C PF12316.3 KLO05635.1 - 7.6 6.5 16.6 0.58 10.2 7.8 1.7 2 0 0 2 2 2 0 Segment polarity protein dishevelled (Dsh) C terminal Mcm10 PF09332.6 KLO05636.1 - 0.16 11.2 2.0 0.23 10.7 0.0 2.2 2 0 0 2 2 2 0 Mcm10 replication factor HP_OMP_2 PF02521.9 KLO05639.1 - 0.028 13.0 0.0 0.036 12.6 0.0 1.2 1 0 0 1 1 1 0 Putative outer membrane protein Pyr_redox_3 PF13738.1 KLO05641.1 - 1.3e-22 80.8 0.0 7.3e-21 75.1 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 KLO05641.1 - 2.5e-21 75.4 0.1 7.2e-14 50.8 0.0 2.4 2 1 0 2 2 2 2 Flavin-binding monooxygenase-like K_oxygenase PF13434.1 KLO05641.1 - 4e-12 45.6 0.0 3.2e-09 36.1 0.0 3.0 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 KLO05641.1 - 1.8e-09 37.7 0.0 7e-07 29.3 0.0 2.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 KLO05641.1 - 9.7e-07 29.1 0.1 0.0039 17.5 0.0 2.7 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.15 KLO05641.1 - 2.7e-06 27.5 0.0 0.0022 18.0 0.0 3.1 3 0 0 3 3 3 1 Shikimate / quinate 5-dehydrogenase NAD_binding_8 PF13450.1 KLO05641.1 - 3.4e-05 23.7 0.0 0.00015 21.6 0.0 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.9 KLO05641.1 - 3.5e-05 22.4 0.1 0.00021 19.9 0.0 2.0 2 0 0 2 2 2 1 HI0933-like protein NAD_binding_9 PF13454.1 KLO05641.1 - 0.00017 21.4 0.0 0.0084 15.8 0.0 2.4 2 0 0 2 2 2 1 FAD-NAD(P)-binding FAD_binding_3 PF01494.14 KLO05641.1 - 0.00033 19.8 0.5 0.0046 16.0 0.0 2.1 2 0 0 2 2 2 1 FAD binding domain FAD_binding_2 PF00890.19 KLO05641.1 - 0.0023 16.8 0.0 0.0053 15.6 0.0 1.6 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 KLO05641.1 - 0.003 16.5 1.7 0.054 12.4 0.1 2.8 3 0 0 3 3 3 1 FAD dependent oxidoreductase NAD_binding_7 PF13241.1 KLO05641.1 - 0.0099 16.1 0.0 0.74 10.1 0.0 2.5 3 0 0 3 3 2 1 Putative NAD(P)-binding TrkA_N PF02254.13 KLO05641.1 - 0.011 15.6 0.0 0.75 9.8 0.0 2.5 2 0 0 2 2 2 0 TrkA-N domain GIDA PF01134.17 KLO05641.1 - 0.022 13.6 1.0 0.76 8.5 0.0 2.7 3 0 0 3 3 3 0 Glucose inhibited division protein A 2-Hacid_dh_C PF02826.14 KLO05641.1 - 0.026 13.6 0.0 0.96 8.5 0.0 2.3 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain FAD_oxidored PF12831.2 KLO05641.1 - 0.056 12.5 0.1 0.082 11.9 0.1 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 KLO05641.1 - 0.098 11.5 0.1 0.36 9.6 0.0 1.9 3 0 0 3 3 3 0 Lycopene cyclase protein DUF3656 PF12392.3 KLO05643.1 - 0.031 14.3 2.1 0.064 13.3 0.2 1.9 1 1 1 2 2 2 0 Collagenase DUF4449 PF14613.1 KLO05644.1 - 5.1e-05 23.2 0.0 0.00027 20.9 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF4449) DUF2733 PF10813.3 KLO05644.1 - 0.11 12.1 1.4 0.23 11.0 1.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2733) F-box-like PF12937.2 KLO05648.1 - 9.7e-06 25.2 0.0 1.7e-05 24.4 0.0 1.4 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KLO05648.1 - 0.0078 15.8 0.0 0.015 14.9 0.0 1.5 1 0 0 1 1 1 1 F-box domain NicO PF03824.11 KLO05649.1 - 7.6e-46 156.6 2.2 7.6e-46 156.6 1.5 2.6 2 1 0 2 2 2 2 High-affinity nickel-transport protein F-box-like PF12937.2 KLO05650.1 - 8.4e-05 22.2 0.1 0.00019 21.0 0.0 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KLO05650.1 - 0.00049 19.6 0.0 0.0014 18.2 0.0 1.8 1 0 0 1 1 1 1 F-box domain CDC37_N PF03234.9 KLO05651.1 - 1.8e-44 152.1 4.0 3.5e-44 151.2 2.8 1.5 1 0 0 1 1 1 1 Cdc37 N terminal kinase binding CDC37_M PF08565.6 KLO05651.1 - 3.7e-32 111.1 0.0 8.1e-32 110.0 0.0 1.5 1 0 0 1 1 1 1 Cdc37 Hsp90 binding domain CDC37_C PF08564.5 KLO05651.1 - 3.7e-19 68.4 0.0 3.7e-19 68.4 0.0 2.2 2 0 0 2 2 2 1 Cdc37 C terminal domain Ebp2 PF05890.7 KLO05652.1 - 2.3e-76 256.6 24.3 3.2e-76 256.2 16.8 1.2 1 0 0 1 1 1 1 Eukaryotic rRNA processing protein EBP2 Daxx PF03344.10 KLO05652.1 - 0.012 14.1 21.3 0.016 13.7 14.7 1.2 1 0 0 1 1 1 0 Daxx Family Acetyltransf_1 PF00583.19 KLO05654.1 - 6.5e-08 32.5 0.0 1.2e-07 31.6 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 KLO05654.1 - 6e-07 29.5 0.0 2.5e-06 27.6 0.0 2.0 2 1 1 3 3 3 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 KLO05654.1 - 0.0008 19.5 0.0 0.0016 18.5 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain DUF3328 PF11807.3 KLO05657.1 - 2e-13 50.5 0.0 3.6e-13 49.6 0.0 1.5 1 1 0 1 1 1 1 Domain of unknown function (DUF3328) DUF3328 PF11807.3 KLO05658.1 - 2.3e-10 40.5 0.4 3.6e-10 39.9 0.1 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF3328) But2 PF09792.4 KLO05659.1 - 3.7e-07 29.9 0.1 6.8e-07 29.1 0.0 1.5 1 1 0 1 1 1 1 Ubiquitin 3 binding protein But2 C-terminal domain CLTH PF10607.4 KLO05660.1 - 2.6e-31 108.2 0.3 4.9e-31 107.3 0.2 1.4 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain zf-RING_UBOX PF13445.1 KLO05660.1 - 0.0028 17.3 0.0 0.041 13.5 0.0 2.4 2 0 0 2 2 2 1 RING-type zinc-finger Oxidored_FMN PF00724.15 KLO05661.1 - 8.1e-69 232.1 0.0 1.5e-68 231.3 0.0 1.4 1 1 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family PcrB PF01884.12 KLO05661.1 - 0.016 14.4 0.8 0.026 13.8 0.0 1.6 2 0 0 2 2 2 0 PcrB family Dus PF01207.12 KLO05661.1 - 0.081 11.7 0.0 1.2 7.9 0.0 2.1 2 0 0 2 2 2 0 Dihydrouridine synthase (Dus) Oxidored_FMN PF00724.15 KLO05662.1 - 1.2e-71 241.4 0.0 1.5e-71 241.1 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family FMN_dh PF01070.13 KLO05662.1 - 0.062 12.1 1.5 1.9 7.2 0.2 2.1 2 0 0 2 2 2 0 FMN-dependent dehydrogenase PcrB PF01884.12 KLO05662.1 - 0.21 10.8 0.8 0.28 10.3 0.0 1.5 2 0 0 2 2 2 0 PcrB family Mem_trans PF03547.13 KLO05663.1 - 1.1e-42 145.7 0.4 3.4e-38 130.9 0.0 2.2 2 0 0 2 2 2 2 Membrane transport protein PCMT PF01135.14 KLO05664.1 - 2.1e-72 243.0 0.0 2.4e-72 242.8 0.0 1.0 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_31 PF13847.1 KLO05664.1 - 5.1e-11 42.3 0.0 1.2e-10 41.1 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 KLO05664.1 - 1e-09 38.9 0.0 1.7e-09 38.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KLO05664.1 - 1.1e-05 25.4 0.0 1.8e-05 24.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KLO05664.1 - 1.4e-05 24.9 0.0 2.2e-05 24.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KLO05664.1 - 0.00016 22.1 0.0 0.0003 21.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain GCD14 PF08704.5 KLO05664.1 - 0.00056 19.4 0.0 0.00081 18.9 0.0 1.2 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit Methyltransf_25 PF13649.1 KLO05664.1 - 0.00086 19.6 0.0 0.0016 18.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KLO05664.1 - 0.0013 18.0 0.0 0.0024 17.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Ubie_methyltran PF01209.13 KLO05664.1 - 0.0018 17.4 0.0 0.0033 16.5 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Fibrillarin PF01269.12 KLO05664.1 - 0.0092 14.9 0.0 0.014 14.2 0.0 1.2 1 0 0 1 1 1 1 Fibrillarin N6_N4_Mtase PF01555.13 KLO05664.1 - 0.012 15.0 0.0 0.076 12.4 0.0 2.0 2 0 0 2 2 2 0 DNA methylase FtsJ PF01728.14 KLO05664.1 - 0.018 15.0 0.0 0.023 14.6 0.0 1.2 1 0 0 1 1 1 0 FtsJ-like methyltransferase PrmA PF06325.8 KLO05664.1 - 0.018 14.1 0.0 0.028 13.5 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) MetW PF07021.7 KLO05664.1 - 0.026 13.9 0.0 0.052 12.9 0.0 1.5 1 1 0 1 1 1 0 Methionine biosynthesis protein MetW Methyltransf_32 PF13679.1 KLO05664.1 - 0.071 12.8 0.0 0.12 12.0 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_3 PF01596.12 KLO05664.1 - 0.073 12.1 0.0 0.13 11.3 0.0 1.4 1 0 0 1 1 1 0 O-methyltransferase Methyltransf_12 PF08242.7 KLO05664.1 - 0.097 13.1 0.0 0.18 12.2 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Nucleo_P87 PF07267.6 KLO05666.1 - 1.8 7.1 8.1 2.7 6.5 5.6 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 CENP-B_dimeris PF09026.5 KLO05666.1 - 3.5 7.9 9.0 8.1 6.7 6.2 1.6 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Transposase_21 PF02992.9 KLO05667.1 - 2e-08 33.5 0.0 3e-08 33.0 0.0 1.2 1 0 0 1 1 1 1 Transposase family tnp2 DUF4218 PF13960.1 KLO05667.1 - 0.00014 21.3 0.4 0.00027 20.3 0.3 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4218) DUF539 PF04400.8 KLO05667.1 - 0.11 12.0 1.4 0.21 11.1 1.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF539) WD40 PF00400.27 KLO05670.1 - 0.00043 20.0 2.6 0.66 9.9 0.0 4.0 5 0 0 5 5 5 3 WD domain, G-beta repeat Adaptin_binding PF10199.4 KLO05671.1 - 1.7 8.8 5.4 3.1 8.0 3.8 1.4 1 1 0 1 1 1 0 Alpha and gamma adaptin binding protein p34 STE3 PF02076.10 KLO05673.1 - 3.2e-47 160.9 12.1 4.3e-47 160.5 8.4 1.2 1 0 0 1 1 1 1 Pheromone A receptor AA_permease_2 PF13520.1 KLO05674.1 - 4.6e-71 239.5 36.9 6.7e-71 239.0 25.6 1.3 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 KLO05674.1 - 8.7e-19 67.2 26.2 1.3e-18 66.6 18.1 1.3 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 KLO05675.1 - 4e-72 243.0 37.1 5.5e-72 242.6 25.7 1.2 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 KLO05675.1 - 1.5e-19 69.7 23.0 2.4e-19 69.0 15.9 1.2 1 0 0 1 1 1 1 Amino acid permease LRR_6 PF13516.1 KLO05676.1 - 0.012 15.6 0.6 1.8 8.9 0.1 4.2 4 0 0 4 4 4 0 Leucine Rich repeat Pro_isomerase PF00160.16 KLO05682.1 - 1.6e-42 145.3 0.3 1.7e-42 145.2 0.2 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Pro_isomerase PF00160.16 KLO05683.1 - 3e-42 144.4 0.5 3.3e-42 144.3 0.3 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD GRASP55_65 PF04495.9 KLO05684.1 - 4.1e-60 201.7 0.0 1.1e-42 145.3 0.0 2.1 1 1 1 2 2 2 2 GRASP55/65 PDZ-like domain PDZ_2 PF13180.1 KLO05684.1 - 0.005 16.7 0.0 2.1 8.2 0.0 2.3 2 0 0 2 2 2 2 PDZ domain DSPc PF00782.15 KLO05685.1 - 2.9e-27 94.8 0.0 4.2e-27 94.3 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 KLO05685.1 - 8.5e-06 25.2 0.0 1.2e-05 24.8 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase CDKN3 PF05706.7 KLO05685.1 - 0.12 11.7 0.0 0.19 11.1 0.0 1.3 1 0 0 1 1 1 0 Cyclin-dependent kinase inhibitor 3 (CDKN3) BTB PF00651.26 KLO05686.1 - 5.7e-05 23.0 0.1 1.7 8.6 0.0 3.3 3 0 0 3 3 3 2 BTB/POZ domain UPF0160 PF03690.8 KLO05687.1 - 1.2e-128 429.0 0.0 1.3e-128 428.8 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0160) CoA_transf_3 PF02515.12 KLO05689.1 - 2.5e-40 137.7 0.0 1e-36 125.9 0.0 2.2 2 0 0 2 2 2 2 CoA-transferase family III Ribosomal_L17 PF01196.14 KLO05689.1 - 0.0061 17.1 0.0 0.012 16.1 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L17 MFS_1 PF07690.11 KLO05690.1 - 4.3e-25 88.1 31.3 6.5e-25 87.5 21.7 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_1 PF07690.11 KLO05691.1 - 6.7e-32 110.5 29.5 1e-31 109.9 20.5 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily NfeD PF01957.13 KLO05691.1 - 0.16 12.1 0.0 0.16 12.1 0.0 3.5 3 2 0 4 4 4 0 NfeD-like C-terminal, partner-binding Herpes_UL73 PF03554.8 KLO05691.1 - 0.8 9.5 4.6 9.6 6.1 0.7 2.7 2 0 0 2 2 2 0 UL73 viral envelope glycoprotein CAAD PF14159.1 KLO05692.1 - 7.3 6.3 14.6 0.18 11.4 0.9 2.9 3 0 0 3 3 3 0 CAAD domains of cyanobacterial aminoacyl-tRNA synthetase DUF3533 PF12051.3 KLO05693.1 - 1.1e-70 238.2 17.8 1.8e-70 237.6 12.4 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3533) DUF3817 PF12823.2 KLO05693.1 - 0.33 11.4 5.2 1.1 9.7 3.6 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF3817) PsbI PF02532.9 KLO05693.1 - 1.1 8.9 5.9 0.26 10.9 0.1 2.9 3 0 0 3 3 3 0 Photosystem II reaction centre I protein (PSII 4.8 kDa protein) FMN_bind_2 PF04299.7 KLO05694.1 - 1.1e-31 109.6 0.0 1.4e-31 109.3 0.0 1.1 1 0 0 1 1 1 1 Putative FMN-binding domain DUF2665 PF11654.3 KLO05695.1 - 7.2e-12 44.6 0.0 1e-11 44.1 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2665) RdRP PF05183.7 KLO05696.1 - 1.1e-82 278.6 0.0 1.5e-82 278.1 0.0 1.1 1 0 0 1 1 1 1 RNA dependent RNA polymerase ATP_bind_1 PF03029.12 KLO05697.1 - 5.5e-77 258.5 0.8 2.9e-76 256.1 0.0 1.9 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein GTP_EFTU PF00009.22 KLO05697.1 - 0.00011 21.7 0.1 0.0024 17.3 0.0 2.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain NACHT PF05729.7 KLO05697.1 - 0.001 18.7 0.0 0.0022 17.6 0.0 1.7 1 0 0 1 1 1 1 NACHT domain AAA_33 PF13671.1 KLO05697.1 - 0.0011 18.8 0.0 0.0024 17.7 0.0 1.7 1 1 0 1 1 1 1 AAA domain cobW PF02492.14 KLO05697.1 - 0.0012 18.2 0.1 0.02 14.3 0.1 2.3 1 1 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain SRP54 PF00448.17 KLO05697.1 - 0.0014 18.0 0.0 0.085 12.2 0.0 2.7 3 0 0 3 3 3 1 SRP54-type protein, GTPase domain CbiA PF01656.18 KLO05697.1 - 0.0031 16.9 2.8 0.0049 16.3 0.7 2.2 1 1 1 2 2 2 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_17 PF13207.1 KLO05697.1 - 0.0037 18.0 0.7 0.016 16.0 0.0 2.2 2 1 0 2 2 2 1 AAA domain AAA_10 PF12846.2 KLO05697.1 - 0.0075 15.7 0.4 0.029 13.8 0.3 1.9 1 1 0 1 1 1 1 AAA-like domain AAA_22 PF13401.1 KLO05697.1 - 0.0085 16.2 0.0 0.026 14.6 0.0 2.0 1 1 0 1 1 1 1 AAA domain PduV-EutP PF10662.4 KLO05697.1 - 0.0093 15.4 0.0 0.31 10.5 0.0 2.7 3 0 0 3 3 3 1 Ethanolamine utilisation - propanediol utilisation FeoB_N PF02421.13 KLO05697.1 - 0.013 14.7 0.0 0.099 11.9 0.0 2.2 2 0 0 2 2 2 0 Ferrous iron transport protein B NB-ARC PF00931.17 KLO05697.1 - 0.016 14.1 0.1 0.051 12.4 0.0 1.8 3 0 0 3 3 3 0 NB-ARC domain G-alpha PF00503.15 KLO05697.1 - 0.024 13.3 3.5 0.37 9.4 0.1 2.7 3 0 0 3 3 3 0 G-protein alpha subunit AAA_30 PF13604.1 KLO05697.1 - 0.027 14.0 0.0 0.059 12.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain ArgK PF03308.11 KLO05697.1 - 0.028 13.1 0.1 1.6 7.4 0.0 2.3 2 0 0 2 2 2 0 ArgK protein Zeta_toxin PF06414.7 KLO05697.1 - 0.032 13.3 0.1 0.16 11.0 0.0 2.0 2 0 0 2 2 2 0 Zeta toxin AAA_16 PF13191.1 KLO05697.1 - 0.038 13.9 0.0 0.16 11.9 0.0 2.0 2 0 0 2 2 2 0 AAA ATPase domain NTPase_1 PF03266.10 KLO05697.1 - 0.044 13.4 0.0 0.29 10.8 0.0 2.1 2 0 0 2 2 2 0 NTPase AAA_19 PF13245.1 KLO05697.1 - 0.092 12.5 0.0 0.21 11.3 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain FtsK_SpoIIIE PF01580.13 KLO05697.1 - 0.13 11.6 1.5 2.3 7.6 0.0 2.4 2 1 0 2 2 2 0 FtsK/SpoIIIE family UPF0079 PF02367.12 KLO05697.1 - 0.14 11.7 0.0 0.25 10.9 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 DUF92 PF01940.11 KLO05698.1 - 2.5e-60 203.4 11.3 3.7e-60 202.9 7.9 1.2 1 0 0 1 1 1 1 Integral membrane protein DUF92 NAD_binding_9 PF13454.1 KLO05699.1 - 0.0076 16.0 0.0 0.025 14.3 0.0 1.9 1 0 0 1 1 1 1 FAD-NAD(P)-binding DUF1752 PF08550.5 KLO05700.1 - 0.037 13.6 0.0 0.055 13.0 0.0 1.3 1 0 0 1 1 1 0 Fungal protein of unknown function (DUF1752) DUF3295 PF11702.3 KLO05701.1 - 6.4e-11 41.9 6.4 6.4e-11 41.9 4.4 2.2 1 1 1 2 2 2 1 Protein of unknown function (DUF3295) DUF1754 PF08555.5 KLO05701.1 - 1.7 9.2 8.5 0.49 11.0 2.2 2.1 2 0 0 2 2 2 0 Eukaryotic family of unknown function (DUF1754) Fungal_trans PF04082.13 KLO05702.1 - 2.5e-30 105.2 0.2 4.4e-30 104.4 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KLO05702.1 - 1.9e-05 24.4 5.5 3.6e-05 23.5 3.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Aldose_epim PF01263.15 KLO05703.1 - 4.1e-25 88.5 0.0 6.8e-24 84.5 0.0 2.5 1 1 0 1 1 1 1 Aldose 1-epimerase TPR_11 PF13414.1 KLO05704.1 - 0.0017 17.9 0.1 0.036 13.6 0.0 2.3 2 0 0 2 2 2 1 TPR repeat ADH_zinc_N PF00107.21 KLO05706.1 - 4.9e-20 71.4 0.0 8.8e-20 70.5 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KLO05706.1 - 8.1e-10 38.4 0.0 1.4e-09 37.6 0.0 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Fapy_DNA_glyco PF01149.19 KLO05707.1 - 1.2e-24 86.8 0.0 2.7e-24 85.7 0.0 1.6 1 0 0 1 1 1 1 Formamidopyrimidine-DNA glycosylase N-terminal domain H2TH PF06831.9 KLO05707.1 - 6.2e-22 77.1 0.0 1.8e-21 75.6 0.0 1.8 2 0 0 2 2 2 1 Formamidopyrimidine-DNA glycosylase H2TH domain FbpA PF05833.6 KLO05707.1 - 0.00063 18.3 0.0 0.001 17.7 0.0 1.3 1 0 0 1 1 1 1 Fibronectin-binding protein A N-terminus (FbpA) Ribosomal_S13 PF00416.17 KLO05707.1 - 0.0067 16.8 0.0 0.033 14.6 0.0 2.0 2 0 0 2 2 2 1 Ribosomal protein S13/S18 Fer2_BFD PF04324.10 KLO05707.1 - 0.08 13.0 0.1 0.21 11.6 0.0 1.7 1 0 0 1 1 1 0 BFD-like [2Fe-2S] binding domain Utp12 PF04003.7 KLO05708.1 - 3.9e-13 49.2 1.8 2.4e-12 46.6 1.2 2.1 1 1 0 1 1 1 1 Dip2/Utp12 Family WD40 PF00400.27 KLO05708.1 - 0.0048 16.7 4.6 0.11 12.4 0.3 4.0 3 0 0 3 3 3 1 WD domain, G-beta repeat RAB3GAP2_N PF14655.1 KLO05708.1 - 0.018 14.1 0.2 0.2 10.6 0.1 2.1 1 1 1 2 2 2 0 Rab3 GTPase-activating protein regulatory subunit N-terminus UTP15_C PF09384.5 KLO05708.1 - 0.082 12.5 0.0 0.16 11.6 0.0 1.4 1 0 0 1 1 1 0 UTP15 C terminal Pkinase PF00069.20 KLO05709.1 - 1.5e-72 243.8 0.0 2.3e-72 243.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KLO05709.1 - 7e-34 117.0 0.3 1.8e-33 115.6 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 KLO05709.1 - 0.00023 20.2 0.0 0.00023 20.2 0.0 1.6 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 KLO05709.1 - 0.02 14.6 4.9 0.31 10.7 0.0 2.4 2 0 0 2 2 2 0 Phosphotransferase enzyme family Med15 PF09606.5 KLO05709.1 - 0.47 8.5 34.5 0.65 8.1 23.9 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal PAT1 PF09770.4 KLO05709.1 - 1.2 7.2 28.1 1.6 6.8 19.5 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 TFIIA PF03153.8 KLO05709.1 - 1.3 8.8 15.4 1.7 8.4 10.6 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF4230 PF14014.1 KLO05709.1 - 3.6 7.4 11.3 5.9 6.7 7.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4230) DUF4407 PF14362.1 KLO05709.1 - 6.3 5.6 9.7 9.2 5.1 6.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) MFS_1 PF07690.11 KLO05710.1 - 9.3e-33 113.3 16.3 1.1e-32 113.1 10.6 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily MFS_1_like PF12832.2 KLO05710.1 - 0.00059 19.5 1.3 0.084 12.6 0.2 2.7 2 1 0 2 2 2 2 MFS_1 like family DUF2919 PF11143.3 KLO05710.1 - 0.14 11.9 6.7 0.44 10.3 4.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2919) RhodobacterPufX PF11511.3 KLO05710.1 - 1.3 8.4 4.2 1.4 8.3 0.0 2.9 3 0 0 3 3 3 0 Intrinsic membrane protein PufX MFS_1 PF07690.11 KLO05711.1 - 9.9e-44 149.4 36.6 1.2e-30 106.4 5.2 2.0 1 1 0 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 KLO05711.1 - 5.3e-08 31.6 23.9 0.00034 19.1 5.3 3.3 2 2 0 3 3 3 3 MFS/sugar transport protein MFS_1_like PF12832.2 KLO05711.1 - 0.00048 19.8 0.4 0.00048 19.8 0.3 3.7 4 0 0 4 4 4 1 MFS_1 like family RhodobacterPufX PF11511.3 KLO05711.1 - 0.11 11.9 2.6 23 4.4 0.0 4.2 5 0 0 5 5 5 0 Intrinsic membrane protein PufX DUF2341 PF10102.4 KLO05712.1 - 0.08 13.1 1.5 0.091 12.9 1.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF2341) DGF-1_C PF11040.3 KLO05712.1 - 0.1 12.4 0.4 0.13 12.1 0.2 1.1 1 0 0 1 1 1 0 Dispersed gene family protein 1 of Trypanosoma cruzi C-terminus WG_beta_rep PF14903.1 KLO05712.1 - 0.11 12.7 0.3 0.32 11.2 0.2 1.8 1 1 0 1 1 1 0 WG containing repeat VirDNA-topo-I_N PF09266.5 KLO05712.1 - 0.11 12.3 1.4 0.18 11.6 1.0 1.3 1 0 0 1 1 1 0 Viral DNA topoisomerase I, N-terminal LHH PF14411.1 KLO05714.1 - 0.11 12.7 0.3 0.12 12.5 0.2 1.1 1 0 0 1 1 1 0 A nuclease of the HNH/ENDO VII superfamily with conserved LHH Antifungal_prot PF11402.3 KLO05714.1 - 0.15 12.3 0.1 0.19 11.9 0.1 1.2 1 0 0 1 1 1 0 Antifungal protein zf-MYND PF01753.13 KLO05720.1 - 8e-10 38.4 19.3 1.6e-09 37.4 13.4 1.5 1 0 0 1 1 1 1 MYND finger FA_desaturase PF00487.19 KLO05721.1 - 4.8e-26 91.7 11.8 7.5e-26 91.1 8.1 1.3 1 0 0 1 1 1 1 Fatty acid desaturase Lipid_DES PF08557.5 KLO05721.1 - 2.1e-17 62.0 0.3 3.5e-17 61.3 0.2 1.4 1 0 0 1 1 1 1 Sphingolipid Delta4-desaturase (DES) Bin3 PF06859.7 KLO05722.1 - 1.7e-35 121.3 0.0 2.7e-35 120.6 0.0 1.3 1 0 0 1 1 1 1 Bicoid-interacting protein 3 (Bin3) Methyltransf_18 PF12847.2 KLO05722.1 - 7.1e-13 49.1 0.0 1.9e-12 47.7 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KLO05722.1 - 1.2e-12 47.8 0.0 1.8e-12 47.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KLO05722.1 - 2.4e-09 36.9 0.0 0.00043 19.8 0.0 2.1 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_12 PF08242.7 KLO05722.1 - 6.5e-07 29.7 0.0 3.2e-05 24.3 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KLO05722.1 - 1.4e-06 28.3 0.0 2.8e-06 27.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KLO05722.1 - 2.4e-05 24.7 0.0 0.04 14.3 0.0 2.3 2 0 0 2 2 2 2 Methyltransferase domain PrmA PF06325.8 KLO05722.1 - 0.0052 15.9 0.0 0.0095 15.0 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.9 KLO05722.1 - 0.0087 15.4 0.0 0.022 14.1 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_4 PF02390.12 KLO05722.1 - 0.079 11.9 0.0 0.19 10.7 0.0 1.6 2 0 0 2 2 2 0 Putative methyltransferase CMAS PF02353.15 KLO05722.1 - 0.12 11.4 0.0 7.6 5.5 0.0 2.1 2 0 0 2 2 2 0 Mycolic acid cyclopropane synthetase Methyltransf_25 PF13649.1 KLO05722.1 - 0.16 12.3 0.0 1.1 9.6 0.0 2.1 1 1 0 1 1 1 0 Methyltransferase domain UCH PF00443.24 KLO05723.1 - 4.4e-45 153.8 0.0 8.8e-45 152.8 0.0 1.5 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 KLO05723.1 - 3.5e-12 46.3 0.4 2.7e-07 30.3 0.0 3.2 2 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase Aminotran_1_2 PF00155.16 KLO05724.1 - 7.6e-60 202.7 0.0 9.2e-60 202.4 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.15 KLO05724.1 - 0.00067 18.0 0.0 0.0017 16.7 0.0 1.6 2 0 0 2 2 2 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.14 KLO05724.1 - 0.0031 16.3 0.0 0.017 13.8 0.0 1.9 2 0 0 2 2 2 1 Aminotransferase class-V Atg14 PF10186.4 KLO05725.1 - 2.8e-39 134.8 0.5 5.2e-24 84.7 0.0 2.1 2 0 0 2 2 2 2 UV radiation resistance protein and autophagy-related subunit 14 YscO PF07321.7 KLO05725.1 - 0.014 15.2 0.9 0.014 15.2 0.6 2.2 2 0 0 2 2 2 0 Type III secretion protein YscO FUSC PF04632.7 KLO05725.1 - 0.081 11.3 3.1 0.12 10.8 2.2 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF4436 PF14494.1 KLO05726.1 - 5.2e-05 22.6 5.0 8.1e-05 22.0 3.5 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4436) ETRAMP PF09716.5 KLO05726.1 - 0.48 10.4 0.0 0.48 10.4 0.0 2.7 4 0 0 4 4 4 0 Malarial early transcribed membrane protein (ETRAMP) zf-MYND PF01753.13 KLO05730.1 - 1.3e-08 34.5 18.3 3.5e-08 33.1 12.7 1.8 1 0 0 1 1 1 1 MYND finger DUF4064 PF13273.1 KLO05730.1 - 0.11 12.6 0.1 0.22 11.6 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4064) zf-MYND PF01753.13 KLO05731.1 - 1.5e-10 40.7 18.4 2e-10 40.3 12.8 1.2 1 0 0 1 1 1 1 MYND finger Peptidase_C33 PF05412.7 KLO05731.1 - 0.0058 16.4 0.3 0.0058 16.4 0.2 1.0 1 0 0 1 1 1 1 Equine arterivirus Nsp2-type cysteine proteinase DUF4216 PF13952.1 KLO05731.1 - 0.1 12.0 0.5 0.23 10.9 0.1 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4216) Act-Frag_cataly PF09192.5 KLO05734.1 - 0.023 13.6 0.1 0.033 13.1 0.1 1.2 1 0 0 1 1 1 0 Actin-fragmin kinase, catalytic DDE_Tnp_4 PF13359.1 KLO05735.1 - 2.7e-28 98.5 0.1 3.7e-28 98.1 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease TetR_N PF00440.18 KLO05735.1 - 0.076 12.6 0.0 0.14 11.8 0.0 1.4 1 0 0 1 1 1 0 Bacterial regulatory proteins, tetR family K_trans PF02705.11 KLO05737.1 - 2e-173 577.5 5.1 5.7e-173 576.1 3.5 1.6 1 1 0 1 1 1 1 K+ potassium transporter F-box-like PF12937.2 KLO05738.1 - 4.5e-10 39.0 0.8 4.5e-10 39.0 0.5 2.3 3 0 0 3 3 3 1 F-box-like Allantoicase PF03561.10 KLO05740.1 - 2.8e-93 309.3 0.0 1e-45 154.9 0.0 2.2 2 0 0 2 2 2 2 Allantoicase repeat Ureidogly_hydro PF04115.7 KLO05740.1 - 1.6e-45 154.3 0.0 2.6e-45 153.7 0.0 1.2 1 0 0 1 1 1 1 Ureidoglycolate hydrolase F5_F8_type_C PF00754.20 KLO05740.1 - 0.018 14.8 0.0 0.55 10.0 0.0 2.5 2 0 0 2 2 2 0 F5/8 type C domain SWI-SNF_Ssr4 PF08549.5 KLO05741.1 - 1e-16 60.4 1.9 3.6e-08 32.1 0.0 2.1 1 1 0 2 2 2 2 Fungal domain of unknown function (DUF1750) Rhomboid_SP PF12595.3 KLO05741.1 - 0.054 13.0 0.2 0.097 12.2 0.1 1.3 1 0 0 1 1 1 0 Rhomboid serine protease DUF2304 PF10066.4 KLO05741.1 - 0.18 11.6 0.1 0.32 10.8 0.1 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2304) BRE1 PF08647.6 KLO05742.1 - 7.7e-08 32.2 9.1 7.7e-08 32.2 6.3 6.4 4 2 1 5 5 5 1 BRE1 E3 ubiquitin ligase zf-C3HC4_2 PF13923.1 KLO05742.1 - 4.7e-07 29.7 11.7 4.7e-07 29.7 8.1 2.6 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KLO05742.1 - 2.1e-06 27.2 12.0 2.1e-06 27.2 8.3 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KLO05742.1 - 2.9e-06 26.8 10.0 8.1e-06 25.4 6.9 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KLO05742.1 - 1.6e-05 24.4 12.1 1.6e-05 24.4 8.4 1.8 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_2 PF13639.1 KLO05742.1 - 2.3e-05 24.1 10.2 5.2e-05 22.9 7.1 1.7 1 0 0 1 1 1 1 Ring finger domain zf-RING_6 PF14835.1 KLO05742.1 - 0.00099 18.8 2.7 0.0023 17.6 1.9 1.5 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-RING_UBOX PF13445.1 KLO05742.1 - 0.2 11.4 6.0 0.62 9.8 4.2 2.0 1 0 0 1 1 1 0 RING-type zinc-finger zf-C3HC4_4 PF15227.1 KLO05742.1 - 4.8 7.1 13.7 0.16 11.8 5.1 1.9 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING Ribosomal_S9 PF00380.14 KLO05743.1 - 3.1e-34 117.8 0.0 5e-34 117.1 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein S9/S16 CASP_C PF08172.7 KLO05744.1 - 1.7e-65 220.4 3.9 1.7e-65 220.4 2.7 3.4 2 1 1 3 3 3 2 CASP C terminal WD40_alt PF14077.1 KLO05744.1 - 0.086 12.4 13.2 0.65 9.6 0.2 4.4 4 0 0 4 4 4 0 Alternative WD40 repeat motif NYD-SP28_assoc PF14775.1 KLO05744.1 - 0.23 11.2 6.7 1.8 8.3 0.5 3.6 3 0 0 3 3 3 0 Sperm tail C-terminal domain BSD PF03909.12 KLO05745.1 - 4.2e-19 68.0 0.1 2.3e-12 46.4 0.0 2.5 2 0 0 2 2 2 2 BSD domain TFIIH_BTF_p62_N PF08567.6 KLO05745.1 - 2.4e-09 36.7 0.2 1e-08 34.6 0.0 2.1 2 0 0 2 2 2 1 TFIIH p62 subunit, N-terminal domain Put_Phosphatase PF06888.7 KLO05746.1 - 2.4e-55 187.2 0.0 2.7e-55 187.1 0.0 1.0 1 0 0 1 1 1 1 Putative Phosphatase HAD_2 PF13419.1 KLO05746.1 - 0.00017 21.8 0.1 0.00064 19.9 0.0 1.8 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase HAD PF12710.2 KLO05746.1 - 0.001 19.2 0.0 0.0018 18.4 0.0 1.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 KLO05746.1 - 0.11 12.9 0.0 0.16 12.3 0.0 1.2 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase Pkinase PF00069.20 KLO05747.1 - 9.6e-52 175.7 0.0 3.6e-51 173.8 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KLO05747.1 - 2.8e-21 75.7 0.0 4.5e-21 75.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 KLO05747.1 - 0.00013 21.7 0.9 0.00028 20.7 0.1 1.9 2 0 0 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.17 KLO05747.1 - 0.0035 16.7 0.0 0.0078 15.5 0.0 1.5 1 0 0 1 1 1 1 RIO1 family DUF4527 PF15030.1 KLO05749.1 - 0.00016 21.1 2.6 0.00016 21.1 1.8 2.0 1 1 1 2 2 2 1 Protein of unknown function (DUF4527) Ead_Ea22 PF13935.1 KLO05749.1 - 0.00089 19.6 0.5 0.0012 19.1 0.4 1.2 1 0 0 1 1 1 1 Ead/Ea22-like protein Urb2 PF10441.4 KLO05749.1 - 0.011 15.4 0.4 0.017 14.7 0.3 1.3 1 0 0 1 1 1 0 Urb2/Npa2 family TMF_TATA_bd PF12325.3 KLO05749.1 - 0.015 14.9 1.8 0.022 14.5 0.8 1.6 1 1 0 1 1 1 0 TATA element modulatory factor 1 TATA binding CytochromB561_N PF09786.4 KLO05749.1 - 0.018 13.5 4.4 0.02 13.3 3.0 1.0 1 0 0 1 1 1 0 Cytochrome B561, N terminal DUF641 PF04859.7 KLO05749.1 - 0.048 13.4 3.4 0.15 11.7 2.3 1.9 1 1 0 1 1 1 0 Plant protein of unknown function (DUF641) Ribonuc_red_sm PF00268.16 KLO05749.1 - 0.082 11.9 0.0 0.1 11.5 0.0 1.3 1 0 0 1 1 1 0 Ribonucleotide reductase, small chain IncA PF04156.9 KLO05749.1 - 0.13 11.8 4.4 0.17 11.4 3.0 1.2 1 0 0 1 1 1 0 IncA protein Geminin PF07412.7 KLO05749.1 - 0.14 11.7 2.3 0.38 10.3 1.7 1.7 1 1 1 2 2 2 0 Geminin CCDC92 PF14916.1 KLO05749.1 - 0.26 10.9 0.1 0.26 10.9 0.1 2.2 3 0 0 3 3 3 0 Coiled-coil domain of unknown function DivIC PF04977.10 KLO05749.1 - 0.29 10.6 8.3 0.047 13.1 1.6 2.4 2 1 1 3 3 3 0 Septum formation initiator Alpha-amylase PF00128.19 KLO05750.1 - 6.5e-75 252.4 0.1 1.1e-74 251.7 0.1 1.3 1 0 0 1 1 1 1 Alpha amylase, catalytic domain Glyco_hydro_3 PF00933.16 KLO05752.1 - 2.5e-49 167.8 0.0 3.4e-49 167.4 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain F-box-like PF12937.2 KLO05753.1 - 1.8e-05 24.3 0.0 7e-05 22.4 0.0 2.0 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KLO05753.1 - 7.8 6.2 8.4 0.64 9.7 0.4 3.2 4 0 0 4 4 4 0 F-box domain Lactamase_B PF00753.22 KLO05756.1 - 4e-12 46.2 0.1 6.4e-12 45.5 0.0 1.3 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 KLO05756.1 - 2e-10 40.5 0.0 4e-10 39.5 0.0 1.5 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Polysacc_lyase PF14099.1 KLO05757.1 - 0.0016 18.1 0.2 0.0034 17.0 0.1 1.7 1 1 0 1 1 1 1 Polysaccharide lyase Amidohydro_4 PF13147.1 KLO05758.1 - 4.3e-20 72.8 6.3 2e-19 70.7 1.3 3.3 2 1 0 2 2 2 1 Amidohydrolase Amidohydro_5 PF13594.1 KLO05758.1 - 1.2e-14 53.8 0.0 5.9e-10 38.8 0.0 2.8 2 0 0 2 2 2 2 Amidohydrolase Amidohydro_1 PF01979.15 KLO05758.1 - 3.1e-10 40.2 0.2 1.6e-07 31.3 0.0 2.7 3 0 0 3 3 3 2 Amidohydrolase family Amidohydro_3 PF07969.6 KLO05758.1 - 1.9e-08 33.9 0.9 1.8e-05 24.1 0.0 3.2 3 0 0 3 3 3 2 Amidohydrolase family Lipase_3 PF01764.20 KLO05759.1 - 7.9e-15 54.7 0.0 1e-14 54.3 0.0 1.2 1 0 0 1 1 1 1 Lipase (class 3) DUF2974 PF11187.3 KLO05759.1 - 0.0042 16.4 0.0 0.023 14.0 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF2974) Lipase_3 PF01764.20 KLO05760.1 - 9.2e-21 73.9 0.0 1.3e-20 73.4 0.0 1.2 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.2 KLO05760.1 - 0.0016 18.3 0.1 0.0023 17.8 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF2974 PF11187.3 KLO05760.1 - 0.1 11.9 0.0 6.8 5.9 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2974) Rad21_Rec8 PF04824.11 KLO05760.1 - 0.16 11.2 0.4 0.26 10.4 0.3 1.3 1 0 0 1 1 1 0 Conserved region of Rad21 / Rec8 like protein F-box-like PF12937.2 KLO05761.1 - 6e-08 32.2 0.1 1.4e-07 31.1 0.1 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KLO05761.1 - 0.0087 15.6 0.9 0.02 14.5 0.1 2.1 2 0 0 2 2 2 1 F-box domain gag-asp_proteas PF13975.1 KLO05765.1 - 4e-07 29.7 0.0 5.5e-07 29.3 0.0 1.3 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.1 KLO05765.1 - 9.1e-06 26.0 0.1 1.6e-05 25.2 0.1 1.4 1 1 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.6 KLO05765.1 - 2.7e-05 24.1 0.0 3.5e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 Retroviral aspartyl protease UBX PF00789.15 KLO05768.1 - 8.2e-12 45.0 0.4 1.6e-11 44.1 0.3 1.5 1 0 0 1 1 1 1 UBX domain PITH PF06201.8 KLO05769.1 - 4.2e-36 124.0 0.0 5.1e-36 123.7 0.0 1.1 1 0 0 1 1 1 1 PITH domain Citrate_synt PF00285.16 KLO05771.1 - 1.3e-99 333.3 0.0 1.8e-99 332.8 0.0 1.2 1 0 0 1 1 1 1 Citrate synthase ADP_ribosyl_GH PF03747.9 KLO05771.1 - 0.1 12.3 0.0 2.8 7.6 0.0 2.5 2 0 0 2 2 2 0 ADP-ribosylglycohydrolase Methyltransf_4 PF02390.12 KLO05772.1 - 2.3e-56 189.9 0.0 4.4e-56 189.0 0.0 1.3 1 1 0 1 1 1 1 Putative methyltransferase Methyltransf_18 PF12847.2 KLO05772.1 - 1e-05 26.0 0.0 2.4e-05 24.8 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KLO05772.1 - 0.0002 21.3 0.0 0.00038 20.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KLO05772.1 - 0.0027 18.0 0.0 0.039 14.3 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.9 KLO05772.1 - 0.0095 15.3 0.0 0.11 11.9 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_12 PF08242.7 KLO05772.1 - 0.016 15.6 0.0 0.049 14.1 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_11 PF08241.7 KLO05772.1 - 0.056 13.9 0.0 5.9 7.4 0.0 3.1 3 0 0 3 3 3 0 Methyltransferase domain FmrO PF07091.6 KLO05772.1 - 0.062 12.2 0.0 0.1 11.5 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA methyltransferase (FmrO) Alba PF01918.16 KLO05773.1 - 0.0012 18.3 0.1 1.9 8.1 0.0 2.7 3 0 0 3 3 3 2 Alba DUF997 PF06196.7 KLO05775.1 - 0.004 16.6 0.2 0.0055 16.1 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF997) APC10 PF03256.11 KLO05776.1 - 7.9e-48 162.6 0.0 9.8e-48 162.3 0.0 1.0 1 0 0 1 1 1 1 Anaphase-promoting complex, subunit 10 (APC10) F5_F8_type_C PF00754.20 KLO05776.1 - 0.0074 16.1 0.0 0.015 15.1 0.0 1.8 1 1 0 1 1 1 1 F5/8 type C domain PHD PF00628.24 KLO05777.1 - 1.5e-07 31.0 6.6 2.8e-07 30.1 4.5 1.5 1 0 0 1 1 1 1 PHD-finger Aminotran_5 PF00266.14 KLO05778.1 - 1.7e-21 76.3 0.0 3e-21 75.5 0.0 1.3 1 1 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.16 KLO05778.1 - 5.1e-08 32.2 0.0 7.6e-08 31.6 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.12 KLO05778.1 - 0.0046 16.0 0.0 0.26 10.2 0.0 2.1 2 0 0 2 2 2 2 DegT/DnrJ/EryC1/StrS aminotransferase family Cu-oxidase_2 PF07731.9 KLO05778.1 - 0.0047 16.4 0.0 0.0047 16.4 0.0 2.0 2 0 0 2 2 2 1 Multicopper oxidase F-box-like PF12937.2 KLO05779.1 - 2.7e-05 23.7 0.6 6.6e-05 22.5 0.0 2.1 2 0 0 2 2 2 1 F-box-like F-box-like PF12937.2 KLO05780.1 - 5.9e-05 22.7 2.8 0.00025 20.6 2.0 2.2 1 1 0 1 1 1 1 F-box-like F-box-like PF12937.2 KLO05781.1 - 0.006 16.2 3.4 0.018 14.7 2.3 1.9 1 1 0 1 1 1 1 F-box-like LRR_8 PF13855.1 KLO05781.1 - 0.055 13.2 3.6 7.6 6.3 0.1 3.7 4 1 0 4 4 4 0 Leucine rich repeat F-box-like PF12937.2 KLO05782.1 - 0.00029 20.4 2.0 0.001 18.7 1.4 2.1 1 1 0 1 1 1 1 F-box-like F-box-like PF12937.2 KLO05783.1 - 0.0039 16.8 5.2 0.0039 16.8 3.6 2.2 2 1 0 2 2 2 1 F-box-like F-box-like PF12937.2 KLO05784.1 - 0.011 15.4 2.5 0.011 15.4 1.7 2.4 2 1 0 2 2 2 0 F-box-like Aldo_ket_red PF00248.16 KLO05785.1 - 1.2e-65 221.1 0.3 1.4e-65 220.9 0.2 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family LOH1CR12 PF10158.4 KLO05785.1 - 0.0062 16.3 0.4 0.094 12.5 0.0 2.1 2 0 0 2 2 2 1 Tumour suppressor protein CDC27 PF09507.5 KLO05788.1 - 2.4 7.2 5.9 4 6.5 4.1 1.4 1 1 0 1 1 1 0 DNA polymerase subunit Cdc27 CDV3 PF15359.1 KLO05788.1 - 6.2 6.9 8.6 1.1 9.3 3.3 1.9 2 1 0 2 2 2 0 Carnitine deficiency-associated protein 3 DUF605 PF04652.11 KLO05788.1 - 6.8 5.9 11.5 6.9 5.9 8.0 1.1 1 0 0 1 1 1 0 Vta1 like ORC6 PF05460.8 KLO05788.1 - 7.6 5.5 10.3 8.1 5.4 7.2 1.1 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) NDUFA12 PF05071.11 KLO05789.1 - 0.2 12.1 4.9 0.26 11.7 0.0 3.0 3 0 0 3 3 3 0 NADH ubiquinone oxidoreductase subunit NDUFA12 KOW PF00467.24 KLO05791.1 - 1.2e-11 43.8 12.0 0.012 15.3 0.0 6.5 6 0 0 6 6 6 5 KOW motif Spt5-NGN PF03439.8 KLO05791.1 - 0.044 13.5 0.0 0.087 12.5 0.0 1.5 1 0 0 1 1 1 0 Early transcription elongation factor of RNA pol II, NGN section Pox_ser-thr_kin PF05445.6 KLO05791.1 - 0.11 11.2 0.0 0.17 10.6 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase zf-B_box PF00643.19 KLO05793.1 - 0.12 12.2 4.6 0.32 10.9 3.2 1.7 1 0 0 1 1 1 0 B-box zinc finger DEAD PF00270.24 KLO05798.1 - 1.1e-09 38.0 0.0 2.1e-09 37.1 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KLO05798.1 - 3.2e-09 36.5 0.0 1.3e-08 34.6 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain Abhydrolase_4 PF08386.5 KLO05805.1 - 1.9e-24 85.5 0.1 3.4e-24 84.7 0.1 1.4 1 0 0 1 1 1 1 TAP-like protein Abhydrolase_1 PF00561.15 KLO05805.1 - 1.6e-19 70.4 0.0 9.8e-19 67.8 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 KLO05805.1 - 8.9e-10 38.8 0.0 1.9e-08 34.4 0.0 2.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_4 PF08386.5 KLO05806.1 - 1.5e-25 89.0 0.0 2.6e-25 88.2 0.0 1.4 1 0 0 1 1 1 1 TAP-like protein Abhydrolase_1 PF00561.15 KLO05806.1 - 3.5e-14 52.9 0.1 2.1e-11 43.8 0.0 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 KLO05806.1 - 4.9e-07 29.8 0.0 1.4e-06 28.3 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_4 PF08386.5 KLO05807.1 - 1e-13 51.0 0.0 1.3e-13 50.6 0.0 1.1 1 0 0 1 1 1 1 TAP-like protein Pkinase PF00069.20 KLO05808.1 - 9.9e-36 123.2 0.0 1.1e-35 123.0 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KLO05808.1 - 2.1e-31 108.9 0.0 3.3e-31 108.2 0.0 1.3 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KLO05808.1 - 0.003 16.5 0.0 0.0042 16.0 0.0 1.2 1 0 0 1 1 1 1 Kinase-like OrfB_Zn_ribbon PF07282.6 KLO05809.1 - 0.33 10.6 2.2 0.66 9.6 1.5 1.5 1 0 0 1 1 1 0 Putative transposase DNA-binding domain Pkinase_Tyr PF07714.12 KLO05813.1 - 3.4e-09 36.1 0.0 5.4e-09 35.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 KLO05813.1 - 5e-09 35.6 0.0 7e-09 35.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain DNA_binding_1 PF01035.15 KLO05814.1 - 4e-27 93.7 0.1 5.3e-27 93.3 0.0 1.2 1 0 0 1 1 1 1 6-O-methylguanine DNA methyltransferase, DNA binding domain HMG_box PF00505.14 KLO05815.1 - 1.2e-14 54.2 0.1 1.5e-14 53.9 0.1 1.1 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 KLO05815.1 - 1.3e-06 28.6 0.0 1.6e-06 28.3 0.0 1.1 1 0 0 1 1 1 1 HMG-box domain HMG_box_5 PF14887.1 KLO05815.1 - 0.088 12.5 0.0 0.11 12.2 0.0 1.1 1 0 0 1 1 1 0 HMG (high mobility group) box 5 DUF605 PF04652.11 KLO05816.1 - 0.1 11.9 18.1 0.15 11.4 12.5 1.3 1 0 0 1 1 1 0 Vta1 like Menin PF05053.8 KLO05816.1 - 2.2 6.3 5.6 2.8 6.0 3.9 1.1 1 0 0 1 1 1 0 Menin Pkinase_Tyr PF07714.12 KLO05817.1 - 8.3e-37 126.6 0.0 1.3e-36 126.0 0.0 1.3 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 KLO05817.1 - 3.2e-35 121.5 0.0 4.5e-35 121.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.1 KLO05817.1 - 0.024 13.6 0.0 0.038 12.9 0.0 1.2 1 0 0 1 1 1 0 Kinase-like zf-B_box PF00643.19 KLO05817.1 - 3.4 7.6 8.0 3 7.8 1.0 3.1 3 0 0 3 3 3 0 B-box zinc finger zf-RanBP PF00641.13 KLO05817.1 - 5.6 6.1 8.9 6.2 6.0 0.0 3.0 3 0 0 3 3 3 0 Zn-finger in Ran binding protein and others Filamin PF00630.14 KLO05818.1 - 0.097 13.2 0.0 0.14 12.7 0.0 1.3 1 0 0 1 1 1 0 Filamin/ABP280 repeat SAM_2 PF07647.12 KLO05822.1 - 0.11 12.4 0.0 0.25 11.2 0.0 1.6 1 1 0 1 1 1 0 SAM domain (Sterile alpha motif) NPV_P10 PF05531.7 KLO05823.1 - 0.14 12.4 0.1 0.29 11.4 0.1 1.5 1 0 0 1 1 1 0 Nucleopolyhedrovirus P10 protein F-box-like PF12937.2 KLO05824.1 - 1e-06 28.3 0.1 2.7e-06 26.9 0.0 1.8 1 0 0 1 1 1 1 F-box-like ATP12 PF07542.6 KLO05824.1 - 0.062 13.2 0.0 0.12 12.3 0.0 1.4 1 0 0 1 1 1 0 ATP12 chaperone protein F-box-like PF12937.2 KLO05825.1 - 8.3e-06 25.4 0.0 2.4e-05 23.9 0.0 1.9 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.2 KLO05825.1 - 0.048 13.3 1.9 3.1 7.5 0.1 4.0 3 0 0 3 3 3 0 Leucine Rich repeats (2 copies) F-box-like PF12937.2 KLO05826.1 - 9.4e-09 34.8 0.1 2.6e-08 33.4 0.0 1.8 1 0 0 1 1 1 1 F-box-like F-box-like PF12937.2 KLO05827.1 - 3.5e-07 29.8 0.0 1.2e-06 28.0 0.0 2.0 2 0 0 2 2 2 1 F-box-like Img2 PF05046.9 KLO05827.1 - 0.025 14.7 0.0 0.062 13.5 0.0 1.6 1 0 0 1 1 1 0 Mitochondrial large subunit ribosomal protein (Img2) G-alpha PF00503.15 KLO05829.1 - 7e-125 416.7 0.3 8.6e-125 416.4 0.2 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 KLO05829.1 - 5.3e-14 51.8 0.2 1.4e-08 34.1 0.1 2.4 2 1 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.7 KLO05829.1 - 0.00055 19.1 0.0 0.43 9.6 0.0 2.3 2 0 0 2 2 2 2 Gtr1/RagA G protein conserved region WAK PF08488.6 KLO05829.1 - 0.013 15.7 0.1 0.074 13.3 0.0 2.1 2 0 0 2 2 2 0 Wall-associated kinase Miro PF08477.8 KLO05829.1 - 0.015 15.8 0.0 0.86 10.1 0.0 2.6 2 0 0 2 2 2 0 Miro-like protein CPT PF07931.7 KLO05829.1 - 0.019 14.6 0.0 0.21 11.2 0.0 2.1 1 1 1 2 2 2 0 Chloramphenicol phosphotransferase-like protein GTP_EFTU PF00009.22 KLO05829.1 - 0.027 13.9 0.0 2.9 7.2 0.0 2.4 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain AAA_29 PF13555.1 KLO05829.1 - 0.039 13.4 0.0 0.076 12.5 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain F-box-like PF12937.2 KLO05832.1 - 1.3e-08 34.4 0.7 3.4e-08 33.0 0.0 2.1 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 KLO05832.1 - 0.0044 16.6 0.4 0.06 13.0 0.3 2.7 1 1 0 1 1 1 1 F-box domain F-box-like PF12937.2 KLO05833.1 - 4.5e-05 23.0 0.0 0.00024 20.7 0.0 2.4 2 0 0 2 2 2 1 F-box-like DUF4473 PF14747.1 KLO05836.1 - 0.021 15.0 0.1 0.043 14.0 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4473) MULE PF10551.4 KLO05838.1 - 2.2e-07 30.9 0.0 7.4e-07 29.2 0.0 1.8 1 0 0 1 1 1 1 MULE transposase domain SWIM PF04434.12 KLO05838.1 - 0.00071 18.9 0.4 0.0016 17.8 0.3 1.5 1 0 0 1 1 1 1 SWIM zinc finger Cauli_VI PF01693.11 KLO05839.1 - 0.069 13.1 0.0 0.2 11.7 0.0 1.8 1 1 0 1 1 1 0 Caulimovirus viroplasmin Peptidase_S9 PF00326.16 KLO05842.1 - 1.9e-09 37.0 0.5 1.1e-07 31.2 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 KLO05842.1 - 7.4e-07 29.0 0.1 1.1e-06 28.5 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KLO05842.1 - 0.035 13.6 0.1 0.06 12.8 0.0 1.6 1 1 0 1 1 1 0 alpha/beta hydrolase fold Ribosomal_L1 PF00687.16 KLO05843.1 - 2.4e-58 197.0 0.5 2.4e-58 197.0 0.3 2.5 2 1 1 3 3 3 1 Ribosomal protein L1p/L10e family ECM1 PF05782.6 KLO05843.1 - 9.1 4.8 11.7 14 4.2 8.1 1.2 1 0 0 1 1 1 0 Extracellular matrix protein 1 (ECM1) MFS_1 PF07690.11 KLO05844.1 - 3.9e-17 62.0 42.5 1.8e-16 59.8 28.0 2.2 1 1 0 1 1 1 1 Major Facilitator Superfamily Methyltransf_16 PF10294.4 KLO05844.1 - 0.12 11.7 0.0 0.25 10.8 0.0 1.4 1 0 0 1 1 1 0 Putative methyltransferase DDHD PF02862.12 KLO05845.1 - 2.7e-34 118.9 3.7 3.4e-22 79.3 0.0 3.0 4 0 0 4 4 4 2 DDHD domain Abhydrolase_5 PF12695.2 KLO05845.1 - 0.046 13.4 0.0 0.17 11.6 0.0 1.9 3 0 0 3 3 3 0 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KLO05845.1 - 0.046 13.5 0.0 0.12 12.2 0.0 1.6 1 0 0 1 1 1 0 Alpha/beta hydrolase family DUF900 PF05990.7 KLO05845.1 - 0.11 11.8 0.1 0.45 9.8 0.0 1.9 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF900) CBM_1 PF00734.13 KLO05846.1 - 1.1e-12 47.3 10.8 1.1e-12 47.3 7.5 2.7 2 0 0 2 2 2 1 Fungal cellulose binding domain ALAD PF00490.16 KLO05849.1 - 7e-119 396.5 0.0 8.5e-119 396.2 0.0 1.0 1 0 0 1 1 1 1 Delta-aminolevulinic acid dehydratase ABC_tran PF00005.22 KLO05852.1 - 2.1e-24 86.3 0.0 4.3e-24 85.3 0.0 1.5 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.14 KLO05852.1 - 8.8e-09 34.9 1.0 0.0006 19.0 0.0 2.2 1 1 1 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 KLO05852.1 - 7.3e-06 26.1 0.0 0.00011 22.3 0.0 2.2 1 1 0 1 1 1 1 AAA domain AAA_13 PF13166.1 KLO05852.1 - 0.00064 18.3 0.0 0.043 12.2 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.1 KLO05852.1 - 0.00097 18.6 0.1 0.002 17.6 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_22 PF13401.1 KLO05852.1 - 0.0034 17.5 0.2 0.13 12.4 0.1 2.3 1 1 0 1 1 1 1 AAA domain AAA_23 PF13476.1 KLO05852.1 - 0.0044 17.3 0.3 0.011 16.1 0.2 1.6 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 KLO05852.1 - 0.0068 17.2 0.2 0.014 16.1 0.1 1.9 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 KLO05852.1 - 0.0076 16.5 0.0 0.034 14.4 0.0 2.0 2 0 0 2 2 2 1 AAA domain SbcCD_C PF13558.1 KLO05852.1 - 0.0082 16.0 0.4 0.02 14.7 0.2 1.7 1 1 0 1 1 1 1 Putative exonuclease SbcCD, C subunit AAA_16 PF13191.1 KLO05852.1 - 0.016 15.1 0.0 0.072 13.0 0.0 1.9 2 0 0 2 2 2 0 AAA ATPase domain DUF258 PF03193.11 KLO05852.1 - 0.022 13.9 0.1 0.068 12.3 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function, DUF258 T2SJ PF11612.3 KLO05852.1 - 0.043 13.5 0.1 0.15 11.8 0.0 1.9 3 0 0 3 3 2 0 Type II secretion system (T2SS), protein J G-alpha PF00503.15 KLO05852.1 - 0.045 12.4 0.0 0.052 12.2 0.0 1.2 1 0 0 1 1 1 0 G-protein alpha subunit AAA_10 PF12846.2 KLO05852.1 - 0.07 12.5 1.4 0.47 9.8 1.0 2.2 1 1 0 1 1 1 0 AAA-like domain FtsK_SpoIIIE PF01580.13 KLO05852.1 - 0.077 12.4 0.0 0.15 11.5 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family NB-ARC PF00931.17 KLO05852.1 - 0.1 11.4 0.0 0.19 10.5 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain AAA_15 PF13175.1 KLO05852.1 - 0.12 11.3 0.0 0.4 9.6 0.0 1.9 2 0 0 2 2 2 0 AAA ATPase domain TilS PF09179.6 KLO05853.1 - 0.099 12.6 0.1 0.2 11.6 0.0 1.4 1 0 0 1 1 1 0 TilS substrate binding domain NIF PF03031.13 KLO05854.1 - 1e-37 129.2 0.1 1.5e-37 128.7 0.0 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase adh_short PF00106.20 KLO05855.1 - 1.7e-05 24.7 0.0 2.8e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KLO05855.1 - 0.00086 19.0 0.0 0.0018 17.9 0.0 1.5 2 0 0 2 2 2 1 KR domain Zn_clus PF00172.13 KLO05856.1 - 0.00021 21.1 12.0 0.00029 20.6 8.4 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF4346 PF14251.1 KLO05856.1 - 0.14 11.8 0.1 0.14 11.8 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4346) Dickkopf_N PF04706.7 KLO05856.1 - 9 6.5 12.1 2.1 8.5 2.9 2.1 1 1 1 2 2 2 0 Dickkopf N-terminal cysteine-rich region Zn_clus PF00172.13 KLO05858.1 - 1.6e-07 31.0 26.9 0.00022 21.0 7.8 2.1 1 1 1 2 2 2 2 Fungal Zn(2)-Cys(6) binuclear cluster domain RNase_T PF00929.19 KLO05859.1 - 4.5e-21 75.8 0.0 6.8e-21 75.2 0.0 1.3 1 0 0 1 1 1 1 Exonuclease Mito_carr PF00153.22 KLO05860.1 - 1.2e-58 194.8 1.7 1.8e-20 72.4 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Colicin_V PF02674.11 KLO05860.1 - 1.3 8.8 5.2 14 5.5 0.0 2.8 3 0 0 3 3 3 0 Colicin V production protein CFEM PF05730.6 KLO05863.1 - 4.7e-07 29.5 9.0 8.2e-07 28.7 6.2 1.4 1 0 0 1 1 1 1 CFEM domain Pex14_N PF04695.8 KLO05863.1 - 6.1 6.9 9.9 11 6.0 0.7 2.2 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Sec6 PF06046.8 KLO05867.1 - 2e-142 475.1 6.4 2e-142 475.1 4.4 1.4 2 0 0 2 2 2 1 Exocyst complex component Sec6 DUF3979 PF13141.1 KLO05867.1 - 0.0033 17.3 0.1 0.55 10.1 0.0 2.6 2 0 0 2 2 2 2 Protein of unknown function (DUF3979) NPV_P10 PF05531.7 KLO05867.1 - 3 8.1 6.0 8.6 6.6 0.8 3.6 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein Vps51 PF08700.6 KLO05867.1 - 9.7 6.1 8.7 2.7 7.9 0.3 3.7 3 1 0 3 3 3 0 Vps51/Vps67 CN_hydrolase PF00795.17 KLO05868.1 - 4.2e-27 94.6 0.0 8.8e-27 93.6 0.0 1.5 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase NAD_synthase PF02540.12 KLO05868.1 - 1.1e-22 80.0 0.0 7.6e-22 77.3 0.0 2.1 1 1 0 1 1 1 1 NAD synthase Beta_elim_lyase PF01212.16 KLO05868.1 - 0.089 11.9 0.1 9.2 5.3 0.0 2.3 1 1 1 2 2 2 0 Beta-eliminating lyase F-box PF00646.28 KLO05869.1 - 1.2e-05 24.7 0.3 4.5e-05 22.9 0.2 2.0 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 KLO05869.1 - 7e-05 22.4 0.2 0.00017 21.1 0.2 1.6 1 0 0 1 1 1 1 F-box-like DEAD PF00270.24 KLO05871.1 - 1.8e-37 128.3 0.0 2.8e-37 127.8 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KLO05871.1 - 3.5e-21 74.8 0.0 4.2e-11 42.5 0.0 2.5 2 0 0 2 2 2 2 Helicase conserved C-terminal domain ResIII PF04851.10 KLO05871.1 - 0.00086 19.1 0.0 0.0026 17.6 0.0 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit CDC45 PF02724.9 KLO05871.1 - 0.0023 16.0 0.8 0.0035 15.4 0.5 1.2 1 0 0 1 1 1 1 CDC45-like protein CMS1 PF14617.1 KLO05871.1 - 0.07 12.1 5.2 0.12 11.4 0.0 2.7 3 0 0 3 3 3 0 U3-containing 90S pre-ribosomal complex subunit Apt1 PF10351.4 KLO05871.1 - 0.12 11.2 2.6 0.22 10.3 1.8 1.3 1 0 0 1 1 1 0 Golgi-body localisation protein domain Kdo PF06293.9 KLO05872.1 - 0.00032 19.8 0.0 0.16 11.0 0.0 2.5 2 0 0 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.20 KLO05872.1 - 0.00045 19.4 0.1 0.0011 18.1 0.1 1.7 1 0 0 1 1 1 1 Protein kinase domain DUF3906 PF13046.1 KLO05872.1 - 0.063 12.9 0.2 0.38 10.4 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3906) STE3 PF02076.10 KLO05873.1 - 8.8e-62 208.7 9.0 1.1e-61 208.4 6.3 1.1 1 0 0 1 1 1 1 Pheromone A receptor PrgI PF12666.2 KLO05873.1 - 0.12 12.5 1.9 1.2 9.3 0.0 3.0 3 0 0 3 3 3 0 PrgI family protein DUF4401 PF14351.1 KLO05873.1 - 0.86 8.5 13.9 0.12 11.3 6.9 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4401) RicinB_lectin_2 PF14200.1 KLO05874.1 - 1.8e-08 34.6 2.1 0.00096 19.4 0.6 2.0 1 1 1 2 2 2 2 Ricin-type beta-trefoil lectin domain-like RicinB_lectin_2 PF14200.1 KLO05876.1 - 2.2e-05 24.7 1.8 0.00038 20.7 0.1 2.6 1 1 1 2 2 2 2 Ricin-type beta-trefoil lectin domain-like Glyco_hydro_43 PF04616.9 KLO05877.1 - 7.5e-36 123.6 0.4 1.1e-35 123.1 0.3 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 adh_short PF00106.20 KLO05878.1 - 1.1e-25 90.5 0.9 1.3e-25 90.2 0.6 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KLO05878.1 - 8.4e-24 84.6 0.1 1.1e-23 84.3 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KLO05878.1 - 5.9e-09 35.8 0.3 7.9e-09 35.4 0.2 1.3 1 0 0 1 1 1 1 KR domain B12-binding PF02310.14 KLO05878.1 - 0.02 14.7 0.8 0.034 14.0 0.3 1.6 2 0 0 2 2 2 0 B12 binding domain DUF948 PF06103.6 KLO05878.1 - 0.022 14.6 0.2 0.058 13.2 0.0 1.8 2 0 0 2 2 1 0 Bacterial protein of unknown function (DUF948) ATP-cone PF03477.11 KLO05878.1 - 0.028 14.8 0.4 0.057 13.8 0.3 1.5 1 0 0 1 1 1 0 ATP cone domain UPF0146 PF03686.8 KLO05878.1 - 0.033 14.0 0.1 0.14 12.0 0.1 2.1 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0146) YjeF_N PF03853.10 KLO05878.1 - 0.04 13.5 0.0 0.21 11.1 0.0 1.9 2 0 0 2 2 2 0 YjeF-related protein N-terminus DUF849 PF05853.7 KLO05878.1 - 0.044 12.6 0.1 0.067 12.0 0.0 1.2 1 0 0 1 1 1 0 Prokaryotic protein of unknown function (DUF849) Toxin_36 PF10550.4 KLO05878.1 - 0.073 14.2 0.6 0.15 13.2 0.5 1.6 1 0 0 1 1 1 0 Conantokin-G mollusc-toxin Enoyl_reductase PF12241.3 KLO05878.1 - 0.087 11.7 0.1 0.14 11.1 0.1 1.3 1 0 0 1 1 1 0 Trans-2-enoyl-CoA reductase catalytic region NAD_binding_10 PF13460.1 KLO05878.1 - 0.1 12.5 1.5 0.35 10.8 1.0 1.9 1 1 0 1 1 1 0 NADH(P)-binding Epimerase PF01370.16 KLO05878.1 - 0.11 11.9 0.3 0.18 11.2 0.2 1.5 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family HHH_5 PF14520.1 KLO05878.1 - 0.38 10.9 2.1 26 5.0 0.1 2.5 2 1 0 2 2 2 0 Helix-hairpin-helix domain adh_short PF00106.20 KLO05879.1 - 2.1e-30 105.8 2.7 2.6e-30 105.5 1.8 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KLO05879.1 - 6.4e-26 91.6 0.1 7.6e-26 91.3 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KLO05879.1 - 1.7e-11 44.1 0.9 2.5e-11 43.5 0.7 1.3 1 1 0 1 1 1 1 KR domain Epimerase PF01370.16 KLO05879.1 - 0.00075 18.9 0.3 0.0017 17.8 0.2 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Luteo_P1-P2 PF08467.5 KLO05879.1 - 0.064 12.0 0.0 0.089 11.5 0.0 1.1 1 0 0 1 1 1 0 Luteovirus RNA polymerase P1-P2/replicase 3Beta_HSD PF01073.14 KLO05879.1 - 0.079 11.6 0.4 0.099 11.3 0.3 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family GST_N_3 PF13417.1 KLO05880.1 - 7.7e-11 42.0 0.1 1.3e-10 41.3 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 KLO05880.1 - 4.1e-07 29.7 0.0 1e-06 28.5 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 KLO05880.1 - 1.9e-06 27.8 0.0 3.3e-06 27.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 KLO05880.1 - 2.6e-06 27.3 0.0 1.4e-05 25.0 0.0 2.1 2 1 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 KLO05880.1 - 0.00061 20.2 0.0 0.00095 19.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 KLO05880.1 - 0.0086 16.2 0.0 0.021 14.9 0.0 1.8 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Glutaredoxin PF00462.19 KLO05880.1 - 0.022 14.7 0.0 0.037 14.0 0.0 1.4 1 0 0 1 1 1 0 Glutaredoxin DEAD PF00270.24 KLO05881.1 - 2.9e-37 127.7 0.0 5.1e-37 126.9 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KLO05881.1 - 7.7e-20 70.5 0.2 2.2e-18 65.9 0.2 2.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain p450 PF00067.17 KLO05882.1 - 1.2e-42 146.0 0.0 1.8e-42 145.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 CTP_synth_N PF06418.9 KLO05883.1 - 2.5e-116 387.6 0.3 3.3e-116 387.2 0.2 1.1 1 0 0 1 1 1 1 CTP synthase N-terminus GATase PF00117.23 KLO05883.1 - 2.3e-52 177.2 0.0 3.8e-52 176.5 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase class-I CbiA PF01656.18 KLO05883.1 - 0.0038 16.6 0.0 0.0065 15.8 0.0 1.3 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain Peptidase_C26 PF07722.8 KLO05883.1 - 0.0063 15.9 0.0 0.026 13.9 0.0 1.9 1 1 0 1 1 1 1 Peptidase C26 DUF4184 PF13803.1 KLO05883.1 - 0.12 11.6 0.0 0.24 10.6 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4184) adh_short PF00106.20 KLO05884.1 - 1.8e-31 109.2 2.0 2.4e-31 108.8 1.4 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KLO05884.1 - 3.6e-20 72.7 0.2 4.6e-20 72.4 0.2 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KLO05884.1 - 9.5e-13 48.2 1.3 1.6e-12 47.4 0.9 1.3 1 0 0 1 1 1 1 KR domain VASP_tetra PF08776.6 KLO05884.1 - 0.011 15.0 0.2 0.023 13.9 0.1 1.5 1 0 0 1 1 1 0 VASP tetramerisation domain adh_short PF00106.20 KLO05885.1 - 1.2e-32 113.1 1.3 1.6e-32 112.6 0.9 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KLO05885.1 - 1.6e-27 96.8 1.3 2e-27 96.5 0.9 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KLO05885.1 - 1.9e-13 50.4 0.5 2.8e-13 49.9 0.4 1.3 1 1 0 1 1 1 1 KR domain adh_short PF00106.20 KLO05886.1 - 2.3e-30 105.7 2.9 2.3e-30 105.7 2.0 1.9 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.1 KLO05886.1 - 1.7e-26 93.4 0.9 2e-26 93.2 0.6 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KLO05886.1 - 8.7e-12 45.0 1.2 8.7e-12 45.0 0.9 1.7 2 1 0 2 2 2 1 KR domain 3Beta_HSD PF01073.14 KLO05886.1 - 8.4e-05 21.4 0.6 0.00013 20.8 0.4 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family B12-binding PF02310.14 KLO05886.1 - 0.0022 17.8 0.3 0.0032 17.3 0.2 1.3 1 0 0 1 1 1 1 B12 binding domain Epimerase PF01370.16 KLO05886.1 - 0.0028 17.1 0.9 0.015 14.7 0.6 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family RuvC PF02075.12 KLO05886.1 - 0.052 13.3 0.6 4.1 7.2 0.0 2.5 1 1 0 2 2 2 0 Crossover junction endodeoxyribonuclease RuvC NAD_binding_10 PF13460.1 KLO05886.1 - 0.5 10.3 3.4 0.65 9.9 0.3 2.5 2 1 0 2 2 2 0 NADH(P)-binding DHH PF01368.15 KLO05887.1 - 0.0001 21.9 0.1 0.00017 21.2 0.1 1.3 1 0 0 1 1 1 1 DHH family Fusion_gly PF00523.13 KLO05889.1 - 0.022 12.8 0.3 0.037 12.1 0.2 1.2 1 0 0 1 1 1 0 Fusion glycoprotein F0 Phage-MuB_C PF09077.6 KLO05889.1 - 0.41 10.3 2.8 0.82 9.3 0.4 2.5 1 1 1 2 2 2 0 Mu B transposition protein, C terminal ubiquitin PF00240.18 KLO05890.1 - 0.028 13.7 0.0 0.088 12.2 0.0 1.8 1 1 0 1 1 1 0 Ubiquitin family Tetraspannin PF00335.15 KLO05893.1 - 3.2e-09 36.3 7.0 4.1e-09 36.0 4.8 1.1 1 0 0 1 1 1 1 Tetraspanin family DUF1713 PF08213.6 KLO05896.1 - 0.023 14.3 0.8 0.038 13.6 0.5 1.4 1 0 0 1 1 1 0 Mitochondrial domain of unknown function (DUF1713) tRNA-synt_2d PF01409.15 KLO05897.1 - 6.7e-47 159.7 0.0 4.9e-27 94.7 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) FDX-ACB PF03147.9 KLO05897.1 - 1.5e-24 85.9 0.0 3.5e-24 84.8 0.0 1.7 1 0 0 1 1 1 1 Ferredoxin-fold anticodon binding domain tRNA-synt_2 PF00152.15 KLO05897.1 - 0.14 10.9 0.6 3.6 6.2 0.0 2.4 3 0 0 3 3 3 0 tRNA synthetases class II (D, K and N) LRR_8 PF13855.1 KLO05900.1 - 0.099 12.4 0.1 4.9 6.9 0.0 3.1 3 0 0 3 3 3 0 Leucine rich repeat RAI16-like PF10257.4 KLO05901.1 - 1.6e-66 224.6 0.0 2.7e-66 223.9 0.0 1.3 1 0 0 1 1 1 1 Retinoic acid induced 16-like protein FPL PF09758.4 KLO05901.1 - 0.15 11.8 0.0 0.35 10.6 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised conserved protein Peroxin-13_N PF04088.8 KLO05902.1 - 7.6e-45 152.6 0.0 1.4e-44 151.8 0.0 1.5 1 0 0 1 1 1 1 Peroxin 13, N-terminal region SH3_2 PF07653.12 KLO05902.1 - 1.2e-10 40.7 0.0 1.9e-10 40.0 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 KLO05902.1 - 1.4e-10 40.3 1.9 0.00027 20.2 1.2 2.3 2 0 0 2 2 2 2 SH3 domain SH3_9 PF14604.1 KLO05902.1 - 3.2e-07 29.8 0.6 6.4e-07 28.8 0.4 1.5 1 1 0 1 1 1 1 Variant SH3 domain Pex14_N PF04695.8 KLO05902.1 - 0.022 14.8 0.8 2.2 8.3 0.5 2.6 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Mucin PF01456.12 KLO05902.1 - 1 9.1 15.5 1.9 8.2 10.8 1.4 1 0 0 1 1 1 0 Mucin-like glycoprotein Zn_clus PF00172.13 KLO05903.1 - 2e-06 27.6 6.5 3.5e-06 26.8 4.5 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Nop16 PF09420.5 KLO05904.1 - 4.4e-35 121.2 0.1 6.3e-35 120.6 0.1 1.2 1 0 0 1 1 1 1 Ribosome biogenesis protein Nop16 QCR10 PF09796.4 KLO05905.1 - 1.8e-16 59.5 0.1 1.9e-16 59.4 0.0 1.0 1 0 0 1 1 1 1 Ubiquinol-cytochrome-c reductase complex subunit (QCR10) DNA_pol_lambd_f PF10391.4 KLO05905.1 - 0.28 10.7 0.1 0.28 10.7 0.1 1.6 2 0 0 2 2 2 0 Fingers domain of DNA polymerase lambda HAD_2 PF13419.1 KLO05906.1 - 1.1e-16 61.5 0.0 5.2e-13 49.6 0.0 2.4 2 1 0 2 2 2 2 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 KLO05906.1 - 0.00015 21.4 0.0 0.00042 19.9 0.0 1.8 2 0 0 2 2 2 1 HAD-hyrolase-like Phe_hydrox_dim PF07976.7 KLO05906.1 - 0.011 15.3 0.0 0.018 14.6 0.0 1.2 1 0 0 1 1 1 0 Phenol hydroxylase, C-terminal dimerisation domain Hydrolase PF00702.21 KLO05906.1 - 0.08 13.3 0.0 0.23 11.8 0.0 2.0 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase His_Phos_2 PF00328.17 KLO05907.1 - 3.6e-52 177.8 0.0 4.5e-52 177.5 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) ParG PF09274.5 KLO05911.1 - 0.022 14.7 0.0 3.7 7.5 0.0 2.5 2 0 0 2 2 2 0 ParG ABC2_membrane PF01061.19 KLO05912.1 - 9e-78 260.2 66.2 1.7e-40 138.4 13.7 3.7 4 0 0 4 4 4 2 ABC-2 type transporter PDR_CDR PF06422.7 KLO05912.1 - 1.5e-34 117.7 0.4 1e-27 95.8 0.0 2.9 2 0 0 2 2 2 2 CDR ABC transporter ABC_tran PF00005.22 KLO05912.1 - 3.5e-28 98.6 0.0 2.5e-14 53.7 0.0 2.7 3 0 0 3 3 3 2 ABC transporter ABC_trans_N PF14510.1 KLO05912.1 - 4.5e-10 39.4 0.1 1e-09 38.3 0.0 1.6 1 0 0 1 1 1 1 ABC-transporter extracellular N-terminal DUF258 PF03193.11 KLO05912.1 - 0.0044 16.2 0.1 0.1 11.7 0.0 2.6 3 0 0 3 3 3 1 Protein of unknown function, DUF258 AAA_25 PF13481.1 KLO05912.1 - 0.011 15.1 0.0 13 5.0 0.0 3.3 3 0 0 3 3 3 0 AAA domain AAA_16 PF13191.1 KLO05912.1 - 0.012 15.6 0.3 1.8 8.5 0.0 2.6 2 0 0 2 2 2 0 AAA ATPase domain ABC2_membrane_3 PF12698.2 KLO05912.1 - 0.052 12.5 49.2 0.42 9.5 16.0 2.9 2 1 0 2 2 2 0 ABC-2 family transporter protein AAA_22 PF13401.1 KLO05912.1 - 0.059 13.5 0.1 4.6 7.3 0.0 3.1 2 1 0 2 2 2 0 AAA domain SbcCD_C PF13558.1 KLO05912.1 - 0.1 12.5 0.0 8.3 6.4 0.0 2.5 2 0 0 2 2 2 0 Putative exonuclease SbcCD, C subunit Hist_deacetyl PF00850.14 KLO05914.1 - 1e-76 258.2 0.0 1.4e-76 257.7 0.0 1.1 1 0 0 1 1 1 1 Histone deacetylase domain KOW PF00467.24 KLO05915.1 - 9e-10 37.8 18.3 0.0012 18.4 0.0 5.9 6 0 0 6 6 6 3 KOW motif Spt5-NGN PF03439.8 KLO05915.1 - 5.9e-09 35.5 0.0 1.3e-08 34.4 0.0 1.6 1 0 0 1 1 1 1 Early transcription elongation factor of RNA pol II, NGN section Harakiri PF15196.1 KLO05915.1 - 0.024 14.8 0.2 0.092 13.0 0.1 1.9 1 0 0 1 1 1 0 Activator of apoptosis harakiri Pyridoxal_deC PF00282.14 KLO05917.1 - 6.3e-63 212.4 0.0 9.2e-63 211.9 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Snurportin1 PF11538.3 KLO05918.1 - 0.04 13.6 1.0 0.12 12.1 0.7 1.8 1 0 0 1 1 1 0 Snurportin1 MatE PF01554.13 KLO05919.1 - 7e-43 146.0 22.3 1.6e-23 83.0 5.2 3.5 3 1 1 4 4 4 2 MatE Polysacc_synt_C PF14667.1 KLO05919.1 - 6.9e-08 32.4 8.3 6.9e-08 32.4 5.8 3.6 3 1 0 3 3 3 1 Polysaccharide biosynthesis C-terminal domain Bac_surface_Ag PF01103.18 KLO05920.1 - 6.6e-38 130.9 0.0 8.9e-38 130.5 0.0 1.2 1 0 0 1 1 1 1 Surface antigen Alpha-L-AF_C PF06964.7 KLO05922.1 - 2.7e-39 134.7 0.1 6.5e-39 133.5 0.1 1.7 1 0 0 1 1 1 1 Alpha-L-arabinofuranosidase C-terminus CBM_4_9 PF02018.12 KLO05922.1 - 0.036 14.0 0.5 0.086 12.8 0.3 1.7 1 0 0 1 1 1 0 Carbohydrate binding domain LSM PF01423.17 KLO05923.1 - 3.3e-07 29.7 0.0 3.8e-07 29.5 0.0 1.2 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 KLO05923.1 - 0.011 15.6 0.0 0.015 15.2 0.0 1.3 1 0 0 1 1 1 0 Ataxin 2 SM domain CBFD_NFYB_HMF PF00808.18 KLO05925.1 - 8.4e-14 51.3 3.5 1.5e-13 50.6 2.4 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 KLO05925.1 - 1.1e-08 35.0 0.9 1.7e-08 34.4 0.6 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Bromo_TP PF07524.8 KLO05925.1 - 0.037 13.7 0.1 0.068 12.9 0.1 1.4 1 0 0 1 1 1 0 Bromodomain associated Na_Ca_ex PF01699.19 KLO05926.1 - 2.6e-20 72.4 28.2 1e-11 44.6 7.2 4.2 5 1 0 5 5 5 2 Sodium/calcium exchanger protein DUF307 PF03733.8 KLO05926.1 - 1.9e-10 40.9 12.8 1.9e-10 40.9 8.9 3.7 3 0 0 3 3 3 1 Domain of unknown function (DUF307) DUF4131 PF13567.1 KLO05926.1 - 0.031 13.6 11.6 1.3 8.3 0.2 4.5 4 0 0 4 4 4 0 Domain of unknown function (DUF4131) MMS1_N PF10433.4 KLO05927.1 - 4e-53 180.2 0.0 7.1e-53 179.4 0.0 1.3 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term CPSF_A PF03178.10 KLO05927.1 - 3.5e-36 124.9 0.0 6.8e-35 120.6 0.0 2.7 2 1 0 2 2 2 1 CPSF A subunit region FtsX PF02687.16 KLO05928.1 - 0.15 11.8 8.0 0.77 9.5 0.0 2.9 2 1 1 3 3 3 0 FtsX-like permease family RSN1_TM PF13967.1 KLO05928.1 - 0.68 9.4 3.9 21 4.6 0.1 2.8 2 1 1 3 3 3 0 Late exocytosis, associated with Golgi transport Polysacc_lyase PF14099.1 KLO05929.1 - 0.079 12.6 0.0 0.11 12.2 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide lyase Yae1_N PF09811.4 KLO05930.1 - 1.4e-10 40.5 5.4 2.2e-10 39.8 3.8 1.3 1 0 0 1 1 1 1 Essential protein Yae1, N terminal SET PF00856.23 KLO05931.1 - 2e-10 41.1 0.0 8e-10 39.2 0.0 1.9 1 1 0 1 1 1 1 SET domain HIT PF01230.18 KLO05932.1 - 5.4e-21 74.9 0.1 1e-20 74.0 0.1 1.4 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.3 KLO05932.1 - 5.9e-13 49.0 0.0 8.9e-13 48.4 0.0 1.3 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding CwfJ_C_1 PF04677.10 KLO05932.1 - 9.3e-07 28.5 0.0 1.5e-06 27.8 0.0 1.4 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 SpoIIP PF07454.6 KLO05932.1 - 0.056 12.6 0.1 0.079 12.1 0.0 1.2 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) XPG_I PF00867.13 KLO05933.1 - 1.5e-17 63.3 0.0 8.1e-17 61.0 0.0 2.0 2 0 0 2 2 2 1 XPG I-region XPG_N PF00752.12 KLO05933.1 - 1.7e-05 24.9 0.0 3.4e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 XPG N-terminal domain DUF3432 PF11914.3 KLO05933.1 - 0.0077 16.2 0.1 0.015 15.3 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3432) Phage_integrase PF00589.17 KLO05934.1 - 0.00077 19.1 0.0 0.74 9.4 0.0 2.2 2 0 0 2 2 2 2 Phage integrase family SAP PF02037.22 KLO05935.1 - 0.00033 20.0 0.5 0.0012 18.3 0.0 2.1 2 0 0 2 2 2 1 SAP domain S4_2 PF13275.1 KLO05935.1 - 0.0079 15.7 0.1 0.014 14.9 0.0 1.4 1 0 0 1 1 1 1 S4 domain Cyclin PF08613.6 KLO05937.1 - 7.1e-08 32.9 0.0 7.1e-08 32.9 0.0 1.0 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.18 KLO05937.1 - 0.0014 18.2 0.0 0.0015 18.1 0.0 1.0 1 0 0 1 1 1 1 Cyclin, N-terminal domain Prok-RING_1 PF14446.1 KLO05938.1 - 0.45 10.2 7.1 0.97 9.2 2.5 2.3 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 PBP1_TM PF14812.1 KLO05938.1 - 0.72 10.1 5.5 1.8 8.8 3.8 1.6 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal PHD PF00628.24 KLO05938.1 - 2.1 8.1 8.1 0.097 12.3 1.5 1.8 2 0 0 2 2 2 0 PHD-finger zf-RING_2 PF13639.1 KLO05938.1 - 5.2 6.9 8.3 1.8 8.4 3.2 2.0 2 0 0 2 2 2 0 Ring finger domain DUF3827 PF12877.2 KLO05943.1 - 1.2 7.1 3.1 1.7 6.6 2.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) Erf4 PF10256.4 KLO05944.1 - 0.00019 21.3 0.0 0.00029 20.6 0.0 1.3 1 0 0 1 1 1 1 Golgin subfamily A member 7/ERF4 family Acetyltransf_1 PF00583.19 KLO05945.1 - 2.4e-09 37.0 0.0 4e-09 36.3 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.5 KLO05945.1 - 7.9e-07 28.7 0.0 1.5e-06 27.8 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.1 KLO05945.1 - 8.4e-05 22.6 0.0 0.00026 21.0 0.0 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 KLO05945.1 - 0.00013 22.0 0.0 0.00024 21.1 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 KLO05945.1 - 0.00019 21.6 0.0 0.00075 19.6 0.0 1.9 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 KLO05945.1 - 0.0036 17.2 0.0 0.04 13.8 0.0 2.0 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 KLO05945.1 - 0.007 16.2 0.0 0.013 15.3 0.0 1.4 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_8 PF13523.1 KLO05945.1 - 0.013 15.3 0.1 0.025 14.4 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain GHL15 PF14885.1 KLO05945.1 - 0.062 13.5 0.0 0.12 12.5 0.0 1.4 1 0 0 1 1 1 0 Hypothetical glycosyl hydrolase family 15 CIAPIN1 PF05093.8 KLO05946.1 - 8.5e-27 93.1 15.5 4.7e-25 87.5 10.7 2.0 1 1 0 1 1 1 1 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis p450 PF00067.17 KLO05947.1 - 9e-64 215.6 0.0 1.1e-63 215.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 NYAP_C PF15452.1 KLO05948.1 - 0.051 12.5 0.2 0.052 12.5 0.1 1.1 1 0 0 1 1 1 0 Neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adapter CIAPIN1 PF05093.8 KLO05949.1 - 1.5e-31 108.4 4.0 2.2e-31 107.8 2.8 1.3 1 0 0 1 1 1 1 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis Fork_head PF00250.13 KLO05950.1 - 1.9e-30 104.7 0.1 3.2e-30 104.0 0.0 1.3 1 0 0 1 1 1 1 Fork head domain zf-HIT PF04438.11 KLO05951.1 - 4.2e-08 32.6 10.7 6.7e-08 32.0 7.4 1.3 1 0 0 1 1 1 1 HIT zinc finger Med18 PF09637.5 KLO05952.1 - 5.6e-08 32.6 0.0 4.6e-06 26.3 0.0 2.0 1 1 1 2 2 2 2 Med18 protein Terpene_synth_C PF03936.11 KLO05953.1 - 2.7e-09 36.6 0.0 3.4e-09 36.3 0.0 1.2 1 0 0 1 1 1 1 Terpene synthase family, metal binding domain p450 PF00067.17 KLO05954.1 - 2.1e-58 197.9 0.0 2.5e-32 112.0 0.0 2.0 2 0 0 2 2 2 2 Cytochrome P450 His_Phos_2 PF00328.17 KLO05954.1 - 0.021 14.1 0.0 0.028 13.7 0.0 1.2 1 0 0 1 1 1 0 Histidine phosphatase superfamily (branch 2) DUF4259 PF14078.1 KLO05954.1 - 0.092 13.2 0.1 0.2 12.1 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4259) p450 PF00067.17 KLO05955.1 - 1.2e-48 165.8 0.0 3.6e-46 157.6 0.0 2.0 2 0 0 2 2 2 2 Cytochrome P450 p450 PF00067.17 KLO05956.1 - 1.9e-10 39.8 0.0 2.1e-10 39.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 WD40 PF00400.27 KLO05957.1 - 0.071 13.0 0.1 0.72 9.8 0.0 2.2 2 0 0 2 2 2 0 WD domain, G-beta repeat CDC45 PF02724.9 KLO05957.1 - 0.49 8.3 4.3 0.58 8.1 3.0 1.1 1 0 0 1 1 1 0 CDC45-like protein TFIIF_alpha PF05793.7 KLO05957.1 - 1.3 7.3 9.5 1.6 7.0 6.6 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) TRAP_alpha PF03896.11 KLO05957.1 - 3.5 6.5 9.5 6.6 5.6 6.6 1.4 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Daxx PF03344.10 KLO05957.1 - 7.6 4.8 12.7 9 4.6 8.8 1.1 1 0 0 1 1 1 0 Daxx Family BSP_II PF05432.6 KLO05959.1 - 1.9 7.6 18.9 0.067 12.4 7.8 2.1 2 0 0 2 2 2 0 Bone sialoprotein II (BSP-II) DPBB_1 PF03330.13 KLO05960.1 - 2.2e-11 43.5 0.1 3e-11 43.1 0.1 1.3 1 0 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Barwin PF00967.12 KLO05960.1 - 1e-08 34.8 1.3 1.1e-08 34.6 0.9 1.1 1 0 0 1 1 1 1 Barwin family Cerato-platanin PF07249.7 KLO05960.1 - 0.028 14.4 0.5 0.031 14.2 0.4 1.1 1 0 0 1 1 1 0 Cerato-platanin zf-Mss51 PF13824.1 KLO05961.1 - 7e-21 73.8 10.9 1.2e-20 73.0 7.5 1.4 1 0 0 1 1 1 1 Zinc-finger of mitochondrial splicing suppressor 51 DUF1610 PF07754.6 KLO05961.1 - 0.03 14.4 0.8 0.03 14.4 0.5 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1610) DUF1438 PF07270.6 KLO05961.1 - 0.12 12.1 0.9 0.36 10.7 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1438) Lar_restr_allev PF14354.1 KLO05961.1 - 0.14 12.4 3.1 0.29 11.4 2.2 1.6 1 0 0 1 1 1 0 Restriction alleviation protein Lar Pex14_N PF04695.8 KLO05961.1 - 0.24 11.4 6.0 0.47 10.4 4.1 1.4 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region IGPD PF00475.13 KLO05962.1 - 1.7e-63 212.7 0.5 2.5e-63 212.2 0.3 1.2 1 0 0 1 1 1 1 Imidazoleglycerol-phosphate dehydratase Glycos_transf_2 PF00535.21 KLO05963.1 - 7e-33 113.6 0.0 8.9e-33 113.3 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.1 KLO05963.1 - 1e-15 58.1 0.0 1.5e-15 57.6 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.4 KLO05963.1 - 2.4e-09 36.6 0.0 3e-09 36.3 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_4 PF13704.1 KLO05963.1 - 0.021 15.1 0.0 0.059 13.6 0.0 1.8 1 1 1 2 2 2 0 Glycosyl transferase family 2 Glyco_trans_2_3 PF13632.1 KLO05963.1 - 0.025 14.3 0.1 0.074 12.7 0.0 1.8 1 1 0 1 1 1 0 Glycosyl transferase family group 2 Glyco_transf_21 PF13506.1 KLO05963.1 - 0.1 11.8 0.0 0.19 10.9 0.0 1.5 1 1 0 1 1 1 0 Glycosyl transferase family 21 Peptidase_M13_N PF05649.8 KLO05964.1 - 1.3e-95 320.7 0.0 1.7e-95 320.3 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M13 Peptidase_M13 PF01431.16 KLO05964.1 - 1e-55 188.1 0.0 1.6e-55 187.4 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M13 ADK PF00406.17 KLO05966.1 - 4.8e-41 140.1 0.0 6.1e-41 139.7 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase ADK_lid PF05191.9 KLO05966.1 - 2.2e-14 52.7 0.0 3.8e-14 52.0 0.0 1.3 1 0 0 1 1 1 1 Adenylate kinase, active site lid AAA_17 PF13207.1 KLO05966.1 - 6.1e-08 33.5 0.0 9.9e-08 32.8 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 KLO05966.1 - 6.8e-05 23.1 0.0 0.00012 22.3 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 KLO05966.1 - 7.6e-05 22.6 0.0 0.00023 21.0 0.0 1.8 1 1 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 KLO05966.1 - 0.0024 17.0 0.0 0.0036 16.4 0.0 1.2 1 0 0 1 1 1 1 Zeta toxin GPI-anchored PF10342.4 KLO05967.1 - 2.2e-09 37.6 1.2 3e-09 37.2 0.9 1.2 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family GPI-anchored PF10342.4 KLO05970.1 - 0.00026 21.3 0.8 0.00053 20.4 0.6 1.5 1 1 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family APH PF01636.18 KLO05971.1 - 2.3e-06 27.5 0.0 2.7e-06 27.2 0.0 1.0 1 0 0 1 1 1 1 Phosphotransferase enzyme family Xan_ur_permease PF00860.15 KLO05972.1 - 3e-61 207.0 33.0 1.8e-59 201.2 22.9 2.2 1 1 0 1 1 1 1 Permease family Pkinase PF00069.20 KLO05974.1 - 1.1e-34 119.8 0.0 4.3e-34 117.8 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KLO05974.1 - 2e-19 69.6 0.0 4.3e-19 68.6 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 KLO05974.1 - 0.0034 17.1 0.0 0.0078 15.9 0.0 1.6 2 0 0 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 KLO05974.1 - 0.0061 16.1 0.0 0.0088 15.6 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase Nucleoplasmin PF03066.10 KLO05974.1 - 0.012 15.0 0.3 0.019 14.4 0.2 1.2 1 0 0 1 1 1 0 Nucleoplasmin Sporozoite_P67 PF05642.6 KLO05974.1 - 0.12 10.2 0.0 0.16 9.8 0.0 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen NOA36 PF06524.7 KLO05974.1 - 0.38 9.9 3.5 0.54 9.4 2.4 1.1 1 0 0 1 1 1 0 NOA36 protein RXT2_N PF08595.6 KLO05974.1 - 0.76 9.5 2.5 1.4 8.7 1.7 1.3 1 0 0 1 1 1 0 RXT2-like, N-terminal PBP1_TM PF14812.1 KLO05974.1 - 2.8 8.3 7.4 5 7.4 5.1 1.3 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal WD40 PF00400.27 KLO05975.1 - 3.4e-33 112.3 22.0 1.3e-10 40.7 0.6 7.5 7 1 1 8 8 8 6 WD domain, G-beta repeat Nup160 PF11715.3 KLO05975.1 - 4.3e-07 28.4 3.8 0.00013 20.2 1.0 2.1 1 1 1 2 2 2 2 Nucleoporin Nup120/160 PD40 PF07676.7 KLO05975.1 - 3e-05 23.5 2.4 0.014 15.0 0.1 4.4 4 0 0 4 4 4 1 WD40-like Beta Propeller Repeat Nbas_N PF15492.1 KLO05975.1 - 0.00022 20.4 0.5 0.0096 15.0 0.0 2.9 3 0 0 3 3 3 1 Neuroblastoma-amplified sequence, N terminal IKI3 PF04762.7 KLO05975.1 - 0.037 11.8 0.1 0.15 9.8 0.0 1.8 2 0 0 2 2 2 0 IKI3 family DUF3312 PF11768.3 KLO05975.1 - 0.15 10.2 0.0 0.69 8.0 0.0 2.0 2 1 0 2 2 2 0 Protein of unknown function (DUF3312) Clathrin PF00637.15 KLO05976.1 - 6.6e-23 80.9 0.0 3.6e-22 78.5 0.0 2.3 2 0 0 2 2 2 1 Region in Clathrin and VPS zf-RING_2 PF13639.1 KLO05976.1 - 0.00011 21.9 3.1 0.00048 19.8 2.1 2.1 1 1 0 1 1 1 1 Ring finger domain WD40 PF00400.27 KLO05976.1 - 0.00072 19.3 0.1 0.0034 17.2 0.2 2.2 2 0 0 2 2 2 1 WD domain, G-beta repeat Vps39_2 PF10367.4 KLO05976.1 - 0.0034 17.5 0.2 0.031 14.4 0.0 2.3 2 0 0 2 2 2 1 Vacuolar sorting protein 39 domain 2 Vps39_1 PF10366.4 KLO05976.1 - 0.0088 16.0 0.1 0.04 13.9 0.0 2.1 2 0 0 2 2 2 1 Vacuolar sorting protein 39 domain 1 zf-RING_5 PF14634.1 KLO05976.1 - 0.023 14.4 1.0 0.079 12.6 0.7 1.9 1 1 0 1 1 1 0 zinc-RING finger domain zf-C3HC4_2 PF13923.1 KLO05976.1 - 0.51 10.3 3.9 1.1 9.3 0.7 2.5 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) ABC2_membrane PF01061.19 KLO05977.1 - 6e-78 260.8 69.6 5.1e-40 136.8 17.7 4.0 4 0 0 4 4 4 2 ABC-2 type transporter ABC_tran PF00005.22 KLO05977.1 - 4.8e-38 130.5 0.0 1.6e-19 70.5 0.0 2.9 3 0 0 3 3 2 2 ABC transporter PDR_CDR PF06422.7 KLO05977.1 - 2.6e-37 126.6 0.2 1.7e-30 104.6 0.0 2.9 2 0 0 2 2 2 2 CDR ABC transporter ABC_trans_N PF14510.1 KLO05977.1 - 4.7e-17 61.8 0.1 9.6e-17 60.8 0.1 1.6 1 0 0 1 1 1 1 ABC-transporter extracellular N-terminal AAA_25 PF13481.1 KLO05977.1 - 1.3e-08 34.4 0.0 0.00024 20.5 0.0 3.2 3 0 0 3 3 3 2 AAA domain AAA_22 PF13401.1 KLO05977.1 - 2.2e-07 31.0 0.1 0.057 13.5 0.0 3.5 2 1 0 2 2 2 2 AAA domain DUF258 PF03193.11 KLO05977.1 - 2.2e-07 30.1 0.0 3.2e-05 23.1 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_16 PF13191.1 KLO05977.1 - 4e-07 30.1 0.1 0.0021 18.0 0.0 2.6 2 0 0 2 2 2 2 AAA ATPase domain NACHT PF05729.7 KLO05977.1 - 0.00027 20.6 0.1 0.091 12.4 0.1 2.9 2 0 0 2 2 2 1 NACHT domain AAA_29 PF13555.1 KLO05977.1 - 0.00038 19.9 0.5 0.049 13.1 0.1 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain MMR_HSR1 PF01926.18 KLO05977.1 - 0.00044 20.1 0.0 1.2 9.0 0.0 2.5 2 0 0 2 2 2 2 50S ribosome-binding GTPase UPF0079 PF02367.12 KLO05977.1 - 0.0014 18.2 0.6 0.16 11.6 0.1 2.7 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 cobW PF02492.14 KLO05977.1 - 0.0031 16.9 0.9 0.28 10.6 0.2 2.3 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain SbcCD_C PF13558.1 KLO05977.1 - 0.0048 16.7 0.0 1.1 9.2 0.0 2.8 2 0 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_21 PF13304.1 KLO05977.1 - 0.0061 16.5 0.0 0.84 9.5 0.0 2.5 3 0 0 3 3 2 1 AAA domain PduV-EutP PF10662.4 KLO05977.1 - 0.0068 15.8 0.3 1.5 8.3 0.1 2.5 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation AAA_19 PF13245.1 KLO05977.1 - 0.0073 16.0 2.0 0.26 11.0 0.2 2.7 2 0 0 2 2 2 1 Part of AAA domain AAA_30 PF13604.1 KLO05977.1 - 0.01 15.4 0.3 1.9 8.0 0.1 2.4 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.1 KLO05977.1 - 0.011 15.6 0.6 0.94 9.4 0.0 2.7 3 0 0 3 3 2 0 AAA domain AAA_10 PF12846.2 KLO05977.1 - 0.012 15.0 0.6 2.7 7.3 0.3 2.5 2 0 0 2 2 2 0 AAA-like domain AAA_18 PF13238.1 KLO05977.1 - 0.016 15.5 0.0 0.86 9.9 0.0 2.4 2 0 0 2 2 2 0 AAA domain Arch_ATPase PF01637.13 KLO05977.1 - 0.019 14.6 0.0 7.8 6.1 0.0 2.6 2 0 0 2 2 2 0 Archaeal ATPase AAA_17 PF13207.1 KLO05977.1 - 0.022 15.5 0.0 0.74 10.6 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.1 KLO05977.1 - 0.023 14.5 0.4 3.2 7.6 0.0 2.8 3 0 0 3 3 2 0 AAA domain FtsK_SpoIIIE PF01580.13 KLO05977.1 - 0.031 13.7 0.0 7.5 5.9 0.0 2.4 2 0 0 2 2 2 0 FtsK/SpoIIIE family SMC_N PF02463.14 KLO05977.1 - 0.05 12.8 0.0 1.1 8.4 0.0 2.6 3 0 0 3 3 3 0 RecF/RecN/SMC N terminal domain AAA PF00004.24 KLO05977.1 - 0.065 13.4 0.1 3.7 7.7 0.0 2.7 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.17 KLO05977.1 - 0.066 13.3 0.0 2.4 8.3 0.0 2.7 3 0 0 3 3 2 0 RNA helicase AAA_23 PF13476.1 KLO05977.1 - 0.085 13.1 0.0 0.49 10.6 0.0 2.0 2 0 0 2 2 2 0 AAA domain Septin PF00735.13 KLO05977.1 - 0.11 11.5 0.1 5.7 5.8 0.1 2.2 2 0 0 2 2 2 0 Septin Miro PF08477.8 KLO05977.1 - 0.12 12.9 0.0 14 6.1 0.0 2.5 2 0 0 2 2 2 0 Miro-like protein ABC2_membrane_3 PF12698.2 KLO05977.1 - 0.17 10.8 67.4 0.0046 16.0 13.2 4.7 3 2 2 5 5 4 0 ABC-2 family transporter protein Pkinase PF00069.20 KLO05979.1 - 9.2e-05 21.7 0.0 0.00011 21.4 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KLO05979.1 - 0.0035 16.4 0.0 0.004 16.2 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 KLO05981.1 - 9.3e-14 51.1 0.0 1.1e-13 50.9 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KLO05981.1 - 9e-09 34.7 0.0 1.1e-08 34.4 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Choline_kinase PF01633.15 KLO05981.1 - 0.0005 19.7 0.0 0.00057 19.5 0.0 1.1 1 0 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.18 KLO05981.1 - 0.0099 15.6 0.0 0.012 15.3 0.0 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 KLO05981.1 - 0.011 14.5 0.0 0.012 14.4 0.0 1.0 1 0 0 1 1 1 0 Seadornavirus VP7 Kdo PF06293.9 KLO05981.1 - 0.15 11.1 0.0 0.16 10.9 0.0 1.0 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Aldo_ket_red PF00248.16 KLO05986.1 - 5e-51 173.2 0.0 5.9e-51 172.9 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family F-box PF00646.28 KLO05987.1 - 5.2e-06 25.9 1.5 1.5e-05 24.4 1.0 1.9 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 KLO05987.1 - 0.00033 20.3 2.1 0.00033 20.3 1.5 2.1 2 0 0 2 2 2 1 F-box-like Omega-toxin PF06357.6 KLO05988.1 - 0.075 12.6 3.6 0.13 11.8 2.5 1.4 1 0 0 1 1 1 0 Omega-atracotoxin Cytochrom_C_asm PF01578.15 KLO05988.1 - 0.093 12.2 0.0 0.11 12.0 0.0 1.1 1 0 0 1 1 1 0 Cytochrome C assembly protein Antifungal_pept PF11410.3 KLO05988.1 - 2.4 8.3 5.9 3.6 7.7 4.1 1.3 1 0 0 1 1 1 0 Antifungal peptide Conotoxin PF02950.12 KLO05988.1 - 6.8 7.5 6.7 1.5 9.6 2.2 1.7 1 1 1 2 2 2 0 Conotoxin F-box-like PF12937.2 KLO05989.1 - 0.0068 16.1 1.1 0.0068 16.1 0.7 2.4 2 0 0 2 2 2 1 F-box-like F-box-like PF12937.2 KLO05990.1 - 1.7e-05 24.4 0.2 6e-05 22.6 0.2 1.9 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KLO05990.1 - 6.2e-05 22.5 0.6 0.00022 20.7 0.4 2.0 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 KLO05991.1 - 0.046 13.4 0.9 0.14 11.8 0.6 1.9 1 0 0 1 1 1 0 F-box-like F-box-like PF12937.2 KLO05992.1 - 4.8e-05 23.0 1.2 0.00015 21.3 0.8 1.9 1 1 0 1 1 1 1 F-box-like F-box PF00646.28 KLO05992.1 - 0.29 10.8 8.1 1.3 8.7 1.0 3.4 3 0 0 3 3 3 0 F-box domain F-box-like PF12937.2 KLO05993.1 - 1.9e-06 27.5 1.8 1.9e-06 27.5 1.2 2.1 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 KLO05993.1 - 0.028 14.0 5.8 0.17 11.5 4.0 2.5 1 1 0 1 1 1 0 F-box domain UPF0220 PF05255.6 KLO05994.1 - 5.8e-50 168.7 0.0 7.7e-50 168.3 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0220) DUF4077 PF13295.1 KLO05994.1 - 0.073 12.7 0.5 0.097 12.3 0.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4077) F-box PF00646.28 KLO05995.1 - 3e-05 23.5 1.5 3e-05 23.5 1.0 2.8 3 0 0 3 3 3 1 F-box domain F-box-like PF12937.2 KLO05995.1 - 5.1e-05 22.9 0.2 0.00019 21.1 0.1 2.0 1 0 0 1 1 1 1 F-box-like F-box-like PF12937.2 KLO05996.1 - 1.2e-05 24.9 0.2 3.6e-05 23.4 0.1 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KLO05996.1 - 0.00055 19.5 0.5 0.0021 17.6 0.4 2.1 1 1 0 1 1 1 1 F-box domain LRR_8 PF13855.1 KLO05996.1 - 0.053 13.2 5.1 0.67 9.7 0.0 4.1 5 0 0 5 5 5 0 Leucine rich repeat LRR_1 PF00560.28 KLO05996.1 - 0.35 11.0 3.9 0.48 10.6 0.1 3.3 3 0 0 3 3 3 0 Leucine Rich Repeat LRR_6 PF13516.1 KLO05996.1 - 0.39 10.9 2.8 11 6.4 0.1 3.9 5 0 0 5 5 5 0 Leucine Rich repeat LRR_2 PF07723.8 KLO05996.1 - 0.91 10.1 3.3 9.1 6.9 0.0 4.0 3 1 0 3 3 3 0 Leucine Rich Repeat LRR_4 PF12799.2 KLO05996.1 - 2.7 7.6 6.8 0.41 10.3 0.1 3.1 4 1 0 4 4 4 0 Leucine Rich repeats (2 copies) F-box-like PF12937.2 KLO05997.1 - 2.2e-06 27.2 0.4 1e-05 25.1 0.3 2.2 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KLO05997.1 - 0.00072 19.1 0.1 0.0024 17.4 0.1 1.9 1 0 0 1 1 1 1 F-box domain Utp13 PF08625.6 KLO06000.1 - 0.0093 15.6 0.0 1.7 8.2 0.0 2.4 2 1 0 2 2 2 2 Utp13 specific WD40 associated domain Ribonuc_red_sm PF00268.16 KLO06008.1 - 2.6e-49 167.7 0.2 2e-33 115.6 0.1 2.1 1 1 1 2 2 2 2 Ribonucleotide reductase, small chain STE3 PF02076.10 KLO06011.1 - 1.9e-59 201.1 8.9 2.2e-59 200.8 6.2 1.1 1 0 0 1 1 1 1 Pheromone A receptor STE3 PF02076.10 KLO06012.1 - 1.9e-56 191.2 11.9 2.2e-56 191.0 8.2 1.0 1 0 0 1 1 1 1 Pheromone A receptor VWA PF00092.23 KLO06013.1 - 0.051 13.2 0.0 0.17 11.5 0.0 1.8 2 0 0 2 2 2 0 von Willebrand factor type A domain Mob1_phocein PF03637.12 KLO06014.1 - 5.5e-24 84.7 0.0 9.6e-24 83.9 0.0 1.3 1 0 0 1 1 1 1 Mob1/phocein family STE3 PF02076.10 KLO06015.1 - 3.6e-51 173.9 5.4 1.2e-49 168.9 3.8 2.0 1 1 0 1 1 1 1 Pheromone A receptor DUF872 PF05915.7 KLO06015.1 - 0.093 12.5 0.0 0.22 11.4 0.0 1.6 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF872) STE3 PF02076.10 KLO06016.1 - 1.9e-62 210.9 7.9 2.2e-62 210.7 5.4 1.0 1 0 0 1 1 1 1 Pheromone A receptor DUF4401 PF14351.1 KLO06016.1 - 0.0084 15.1 7.7 0.014 14.4 5.4 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4401) DUF3040 PF11239.3 KLO06016.1 - 1 9.4 5.0 7 6.7 0.3 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF3040) STE3 PF02076.10 KLO06017.1 - 1.1e-62 211.7 6.0 1.3e-62 211.4 4.2 1.1 1 0 0 1 1 1 1 Pheromone A receptor STE3 PF02076.10 KLO06018.1 - 2.9e-62 210.3 7.7 3.6e-62 210.0 5.4 1.1 1 0 0 1 1 1 1 Pheromone A receptor Hanta_G1 PF01567.11 KLO06018.1 - 0.079 11.2 0.7 0.12 10.5 0.5 1.2 1 0 0 1 1 1 0 Hantavirus glycoprotein G1 TFIIA_gamma_N PF02268.11 KLO06019.1 - 1.3e-25 88.6 0.1 1.9e-25 88.1 0.1 1.2 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit, helical domain TFIIA_gamma_C PF02751.9 KLO06019.1 - 9.4e-20 70.1 2.0 1.4e-19 69.6 1.4 1.2 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit Scytalone_dh PF02982.9 KLO06019.1 - 0.095 12.2 0.0 0.11 12.0 0.0 1.2 1 0 0 1 1 1 0 Scytalone dehydratase STE3 PF02076.10 KLO06020.1 - 5.3e-66 222.5 6.7 6.4e-66 222.3 4.6 1.1 1 0 0 1 1 1 1 Pheromone A receptor DUF4117 PF13491.1 KLO06025.1 - 1.3 8.4 15.1 0.018 14.4 1.9 2.3 1 1 2 3 3 3 0 Domain of unknown function (DUF4117) DUF3328 PF11807.3 KLO06026.1 - 6.8e-17 61.8 0.1 1.2e-16 61.0 0.1 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF3328) Acetyltransf_1 PF00583.19 KLO06032.1 - 1.8e-13 50.3 0.1 2.9e-13 49.6 0.1 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 KLO06032.1 - 1.8e-11 44.0 0.2 1.2e-10 41.3 0.1 2.1 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 KLO06032.1 - 2e-08 34.3 0.0 1.2e-07 31.8 0.0 2.2 1 1 2 3 3 3 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 KLO06032.1 - 3.5e-05 23.6 0.0 0.0005 19.9 0.0 2.2 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 KLO06032.1 - 0.00036 20.4 0.2 0.00067 19.5 0.1 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain GNAT_acetyltr_2 PF13718.1 KLO06032.1 - 0.0024 17.2 0.0 0.0037 16.6 0.0 1.2 1 0 0 1 1 1 1 GNAT acetyltransferase 2 FR47 PF08445.5 KLO06032.1 - 0.0056 16.4 0.0 0.0095 15.6 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_6 PF13480.1 KLO06032.1 - 0.024 14.5 0.1 3.3 7.6 0.0 2.5 2 1 0 2 2 2 0 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 KLO06032.1 - 0.024 14.4 0.0 0.047 13.5 0.0 1.5 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Acetyltransf_3 PF13302.1 KLO06032.1 - 0.094 12.8 0.1 0.13 12.3 0.1 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain DUF3749 PF12568.3 KLO06032.1 - 0.1 12.1 0.0 0.21 11.1 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain MOZ_SAS PF01853.13 KLO06032.1 - 0.13 11.4 0.0 0.22 10.7 0.0 1.2 1 0 0 1 1 1 0 MOZ/SAS family DUF3328 PF11807.3 KLO06033.1 - 3e-17 63.0 0.1 4.1e-17 62.6 0.1 1.3 1 1 0 1 1 1 1 Domain of unknown function (DUF3328) But2 PF09792.4 KLO06034.1 - 0.064 13.0 0.0 1.5 8.5 0.0 2.4 2 0 0 2 2 2 0 Ubiquitin 3 binding protein But2 C-terminal domain Glyco_trans_2_3 PF13632.1 KLO06036.1 - 1.9e-50 171.2 3.0 1.9e-50 171.2 2.1 1.8 2 0 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 KLO06036.1 - 6e-10 39.3 0.6 6e-09 36.0 0.4 2.1 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.21 KLO06036.1 - 0.00099 18.8 0.0 0.071 12.7 0.0 2.5 3 0 0 3 3 3 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.1 KLO06036.1 - 0.0059 15.9 0.0 0.014 14.7 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferase family 21 DDE_Tnp_4 PF13359.1 KLO06041.1 - 4.2e-07 29.6 0.0 6.1e-07 29.1 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.9 KLO06041.1 - 0.00047 19.5 0.0 0.00057 19.3 0.0 1.1 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1_2 PF13586.1 KLO06041.1 - 0.0026 17.9 0.0 0.0048 17.0 0.0 1.5 1 0 0 1 1 1 1 Transposase DDE domain Myb_DNA-bind_3 PF12776.2 KLO06042.1 - 2.5e-06 28.0 0.4 3.2e-06 27.6 0.3 1.2 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_4 PF13837.1 KLO06042.1 - 0.00012 22.1 0.2 0.00016 21.7 0.1 1.4 1 1 0 1 1 1 1 Myb/SANT-like DNA-binding domain DUF2690 PF10901.3 KLO06042.1 - 0.049 13.6 0.7 0.054 13.4 0.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2690) Myb_DNA-bind_5 PF13873.1 KLO06042.1 - 0.15 11.9 1.6 0.17 11.8 0.3 1.6 1 1 1 2 2 2 0 Myb/SANT-like DNA-binding domain 1-cysPrx_C PF10417.4 KLO06048.1 - 0.014 15.0 0.0 0.037 13.6 0.0 1.7 1 0 0 1 1 1 0 C-terminal domain of 1-Cys peroxiredoxin F-box-like PF12937.2 KLO06049.1 - 2.5e-09 36.7 1.2 2.5e-09 36.7 0.8 2.1 2 1 0 2 2 2 1 F-box-like F-box PF00646.28 KLO06049.1 - 0.051 13.2 1.3 0.91 9.2 0.2 2.5 2 0 0 2 2 2 0 F-box domain DUF3684 PF12449.3 KLO06050.1 - 0.019 12.5 0.0 0.023 12.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3684) Nop14 PF04147.7 KLO06051.1 - 0.43 8.4 7.6 0.076 10.9 1.6 2.0 2 0 0 2 2 2 0 Nop14-like family TPR_11 PF13414.1 KLO06052.1 - 1.6e-38 130.1 18.3 9.9e-13 47.5 0.3 5.9 3 2 1 5 5 5 5 TPR repeat TPR_1 PF00515.23 KLO06052.1 - 1.9e-25 87.3 1.2 0.00026 20.4 0.1 7.9 8 0 0 8 8 7 5 Tetratricopeptide repeat TPR_2 PF07719.12 KLO06052.1 - 1.9e-24 83.5 11.7 0.0025 17.5 0.3 8.9 9 0 0 9 9 9 6 Tetratricopeptide repeat DnaJ PF00226.26 KLO06052.1 - 3.4e-22 77.9 0.1 1e-21 76.4 0.1 1.9 1 0 0 1 1 1 1 DnaJ domain TPR_9 PF13371.1 KLO06052.1 - 4.9e-14 51.9 15.5 2.3e-05 24.1 0.9 4.1 4 1 0 4 4 3 3 Tetratricopeptide repeat TPR_16 PF13432.1 KLO06052.1 - 2.9e-13 50.0 30.5 0.00026 21.5 0.2 6.3 6 1 1 7 7 6 4 Tetratricopeptide repeat TPR_12 PF13424.1 KLO06052.1 - 4.4e-12 45.7 14.1 4.2e-07 29.8 0.0 5.4 5 1 1 6 6 5 2 Tetratricopeptide repeat TPR_14 PF13428.1 KLO06052.1 - 1.3e-11 44.0 28.4 0.00081 19.8 0.0 8.0 6 3 3 9 9 7 4 Tetratricopeptide repeat TPR_19 PF14559.1 KLO06052.1 - 2.1e-08 34.3 15.9 0.00051 20.3 0.3 5.4 3 2 2 5 5 5 2 Tetratricopeptide repeat TPR_8 PF13181.1 KLO06052.1 - 6.5e-08 31.8 0.0 0.082 12.7 0.0 4.7 4 0 0 4 4 4 2 Tetratricopeptide repeat Apc3 PF12895.2 KLO06052.1 - 6.6e-08 32.5 2.8 0.0067 16.5 0.0 3.8 3 1 0 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 Fis1_TPR_C PF14853.1 KLO06052.1 - 1.4e-05 24.8 0.2 0.34 10.8 0.1 3.2 3 0 0 3 3 2 2 Fis1 C-terminal tetratricopeptide repeat TPR_15 PF13429.1 KLO06052.1 - 2.7e-05 23.3 10.4 0.19 10.7 0.0 4.2 2 2 2 5 5 5 2 Tetratricopeptide repeat TPR_17 PF13431.1 KLO06052.1 - 5.4e-05 23.0 8.5 4.6 7.7 0.0 6.7 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_7 PF13176.1 KLO06052.1 - 0.00019 21.0 7.5 2.1 8.3 0.2 5.6 5 2 1 6 6 6 1 Tetratricopeptide repeat SHNi-TPR PF10516.4 KLO06052.1 - 0.00027 20.1 0.4 0.022 13.9 0.1 3.7 3 0 0 3 3 3 1 SHNi-TPR Coatomer_E PF04733.9 KLO06052.1 - 0.0074 15.5 1.5 3.2 6.8 0.0 3.1 3 0 0 3 3 3 2 Coatomer epsilon subunit TPR_6 PF13174.1 KLO06052.1 - 0.021 15.2 7.9 1.7 9.2 0.0 6.1 7 0 0 7 7 5 0 Tetratricopeptide repeat RPT PF13446.1 KLO06052.1 - 0.032 13.6 0.0 24 4.4 0.0 3.6 3 0 0 3 3 3 0 A repeated domain in UCH-protein DUF2802 PF10975.3 KLO06052.1 - 0.092 12.5 0.1 0.28 10.9 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2802) TPR_4 PF07721.9 KLO06052.1 - 5.8 7.6 13.1 40 5.0 0.0 5.3 5 0 0 5 5 4 0 Tetratricopeptide repeat GMC_oxred_N PF00732.14 KLO06053.1 - 2.2e-58 197.7 0.0 2.9e-58 197.3 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 KLO06053.1 - 4.3e-40 137.3 0.0 1.2e-39 135.8 0.0 1.8 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.19 KLO06053.1 - 1.2e-06 27.6 0.5 4.3e-05 22.5 0.0 2.2 2 0 0 2 2 2 1 FAD binding domain DAO PF01266.19 KLO06053.1 - 1.4e-06 27.4 0.4 4.7e-06 25.7 0.1 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 KLO06053.1 - 1.8e-06 27.1 0.2 2.7e-06 26.5 0.1 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein Thi4 PF01946.12 KLO06053.1 - 5.3e-05 22.4 0.1 0.0001 21.4 0.0 1.3 1 0 0 1 1 1 1 Thi4 family NAD_binding_8 PF13450.1 KLO06053.1 - 6.6e-05 22.8 0.2 0.0002 21.2 0.1 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 KLO06053.1 - 0.00041 20.2 0.0 0.0007 19.5 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 KLO06053.1 - 0.0056 15.1 0.3 0.008 14.6 0.2 1.2 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox PF00070.22 KLO06053.1 - 0.028 14.8 0.3 0.091 13.1 0.2 1.9 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase GDI PF00996.13 KLO06053.1 - 0.092 11.0 0.0 0.16 10.2 0.0 1.3 1 0 0 1 1 1 0 GDP dissociation inhibitor Trp_halogenase PF04820.9 KLO06053.1 - 0.12 11.0 0.3 0.17 10.4 0.2 1.2 1 0 0 1 1 1 0 Tryptophan halogenase GIDA PF01134.17 KLO06053.1 - 0.13 11.0 0.1 0.2 10.4 0.0 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A GCS PF03074.11 KLO06054.1 - 0.039 13.0 0.0 0.047 12.7 0.0 1.1 1 0 0 1 1 1 0 Glutamate-cysteine ligase AAA PF00004.24 KLO06057.1 - 0.091 12.9 0.0 0.12 12.5 0.0 1.2 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Dickkopf_N PF04706.7 KLO06059.1 - 0.63 10.2 4.6 1.3 9.2 3.2 1.5 1 0 0 1 1 1 0 Dickkopf N-terminal cysteine-rich region DUF2207 PF09972.4 KLO06065.1 - 0.051 12.1 0.0 0.086 11.4 0.0 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) zf-MYND PF01753.13 KLO06066.1 - 3.3e-05 23.6 10.0 3.3e-05 23.6 6.9 1.8 2 0 0 2 2 2 1 MYND finger G-7-MTase PF12803.2 KLO06066.1 - 0.074 12.1 0.0 0.11 11.5 0.0 1.2 1 0 0 1 1 1 0 mRNA (guanine-7-)methyltransferase (G-7-MTase) zf-Mss51 PF13824.1 KLO06066.1 - 0.51 10.2 4.3 1.5 8.7 3.0 1.8 1 0 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 DUF3860 PF12976.2 KLO06067.1 - 0.036 13.8 0.1 0.069 12.9 0.1 1.4 1 0 0 1 1 1 0 Domain of Unknown Function with PDB structure (DUF3860) Zn_Tnp_IS91 PF14319.1 KLO06067.1 - 0.081 12.4 0.3 0.18 11.3 0.0 1.6 2 0 0 2 2 2 0 Transposase zinc-binding domain DDE_1 PF03184.14 KLO06069.1 - 2e-32 112.0 0.2 9.2e-32 109.9 0.1 1.9 1 1 0 1 1 1 1 DDE superfamily endonuclease DDE_3 PF13358.1 KLO06069.1 - 6.7e-08 32.3 0.0 9.6e-08 31.8 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease CDP-OH_P_transf PF01066.16 KLO06071.1 - 4.5e-16 59.0 4.4 4.5e-16 59.0 3.0 2.3 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase HTH_Tnp_Tc5 PF03221.11 KLO06072.1 - 0.057 13.2 0.0 0.12 12.2 0.0 1.6 1 1 0 1 1 1 0 Tc5 transposase DNA-binding domain DDE_1 PF03184.14 KLO06073.1 - 6e-21 74.5 0.0 1.2e-12 47.4 0.0 2.0 1 1 1 2 2 2 2 DDE superfamily endonuclease DDE_3 PF13358.1 KLO06073.1 - 0.0015 18.2 0.0 0.002 17.8 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease CcdA PF07362.7 KLO06074.1 - 0.019 14.8 1.8 0.041 13.7 1.2 1.6 1 0 0 1 1 1 0 Post-segregation antitoxin CcdA Phage_Mu_Gam PF07352.7 KLO06074.1 - 0.16 11.4 3.2 7.2 6.1 0.0 2.8 2 2 0 2 2 2 0 Bacteriophage Mu Gam like protein Complex1_49kDa PF00346.14 KLO06075.1 - 1.3e-126 421.1 0.0 1.8e-126 420.6 0.0 1.2 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 49 Kd subunit NiFeSe_Hases PF00374.14 KLO06075.1 - 0.051 12.3 0.0 0.088 11.5 0.0 1.4 1 0 0 1 1 1 0 Nickel-dependent hydrogenase SMP PF04927.7 KLO06076.1 - 0.0012 18.7 3.8 0.0012 18.7 2.6 1.9 1 1 1 2 2 2 1 Seed maturation protein RTC4 PF14474.1 KLO06079.1 - 1.6e-05 24.8 0.0 3.1e-05 23.9 0.0 1.5 1 0 0 1 1 1 1 RTC4-like domain Thioredoxin_8 PF13905.1 KLO06079.1 - 0.068 13.2 0.0 0.15 12.1 0.0 1.5 1 0 0 1 1 1 0 Thioredoxin-like Thioredoxin_2 PF13098.1 KLO06079.1 - 0.12 12.5 0.0 0.37 11.0 0.0 1.8 2 0 0 2 2 2 0 Thioredoxin-like domain Pkinase PF00069.20 KLO06082.1 - 2.8e-42 144.6 0.0 3.9e-42 144.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KLO06082.1 - 8.6e-39 133.1 0.0 1.3e-38 132.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KLO06082.1 - 0.0052 15.7 0.0 0.0099 14.8 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 KLO06082.1 - 0.014 14.4 0.0 0.03 13.3 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 KLO06082.1 - 0.023 14.0 0.2 0.055 12.8 0.0 1.7 2 0 0 2 2 2 0 RIO1 family APH PF01636.18 KLO06082.1 - 0.053 13.2 0.1 0.35 10.5 0.0 2.2 2 1 0 3 3 3 0 Phosphotransferase enzyme family 1-cysPrx_C PF10417.4 KLO06085.1 - 0.073 12.7 0.3 0.11 12.1 0.2 1.2 1 0 0 1 1 1 0 C-terminal domain of 1-Cys peroxiredoxin Ribosomal_S3Ae PF01015.13 KLO06086.1 - 0.06 12.6 0.4 0.069 12.4 0.3 1.1 1 0 0 1 1 1 0 Ribosomal S3Ae family Pkinase PF00069.20 KLO06091.1 - 1.6e-43 148.7 0.0 2.5e-43 148.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KLO06091.1 - 1.4e-37 129.1 0.0 2e-37 128.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.17 KLO06091.1 - 0.0095 15.3 0.0 0.053 12.8 0.0 2.0 2 0 0 2 2 2 1 RIO1 family Kinase-like PF14531.1 KLO06091.1 - 0.02 13.8 0.0 0.046 12.6 0.0 1.5 1 1 0 1 1 1 0 Kinase-like Kdo PF06293.9 KLO06091.1 - 0.13 11.3 0.0 0.24 10.4 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Methyltransf_2 PF00891.13 KLO06094.1 - 3e-29 101.9 0.0 8e-29 100.5 0.0 1.6 1 1 0 1 1 1 1 O-methyltransferase Methyltransf_18 PF12847.2 KLO06094.1 - 1e-05 26.0 0.0 2.1e-05 25.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 KLO06094.1 - 0.0054 15.7 0.0 0.011 14.7 0.0 1.5 1 0 0 1 1 1 1 Putative methyltransferase Dimerisation PF08100.6 KLO06094.1 - 0.0073 16.1 0.0 0.016 14.9 0.0 1.5 1 0 0 1 1 1 1 Dimerisation domain MTS PF05175.9 KLO06094.1 - 0.058 12.7 0.0 0.11 11.8 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_12 PF08242.7 KLO06094.1 - 0.11 13.0 0.0 0.21 12.0 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_2 PF00891.13 KLO06095.1 - 6.6e-30 104.0 0.0 1.6e-29 102.8 0.0 1.5 1 1 0 1 1 1 1 O-methyltransferase Methyltransf_18 PF12847.2 KLO06095.1 - 4.4e-07 30.4 0.0 8.7e-07 29.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KLO06095.1 - 0.005 16.5 0.0 0.015 15.0 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KLO06095.1 - 0.0059 16.2 0.0 0.032 13.8 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_4 PF02390.12 KLO06095.1 - 0.0068 15.4 0.0 0.011 14.7 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase MTS PF05175.9 KLO06095.1 - 0.032 13.6 0.0 0.066 12.5 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_12 PF08242.7 KLO06095.1 - 0.14 12.6 0.0 0.28 11.6 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain p450 PF00067.17 KLO06097.1 - 2.5e-71 240.6 0.0 2.9e-71 240.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 zf-C2H2_2 PF12756.2 KLO06098.1 - 0.063 13.4 0.2 0.11 12.6 0.1 1.3 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) DUF2201_N PF13203.1 KLO06098.1 - 0.16 11.0 4.0 0.23 10.5 2.8 1.1 1 0 0 1 1 1 0 Putative metallopeptidase domain Nop14 PF04147.7 KLO06098.1 - 0.23 9.3 11.8 0.26 9.1 8.2 1.1 1 0 0 1 1 1 0 Nop14-like family zf-C2H2_jaz PF12171.3 KLO06098.1 - 0.3 11.2 1.4 0.49 10.6 0.9 1.3 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding RR_TM4-6 PF06459.7 KLO06098.1 - 1.5 8.6 6.5 1.9 8.2 4.5 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 BUD22 PF09073.5 KLO06098.1 - 3.7 6.4 14.5 4.5 6.2 10.1 1.1 1 0 0 1 1 1 0 BUD22 Daxx PF03344.10 KLO06098.1 - 3.8 5.8 12.4 4.2 5.7 8.6 1.2 1 0 0 1 1 1 0 Daxx Family SLY PF12485.3 KLO06098.1 - 5.1 7.3 9.5 0.13 12.4 2.1 1.6 2 0 0 2 2 2 0 Lymphocyte signaling adaptor protein Pkinase PF00069.20 KLO06099.1 - 3.2e-46 157.5 0.0 4.6e-26 91.5 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 KLO06099.1 - 1.1e-22 80.3 0.0 4.7e-12 45.5 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 KLO06099.1 - 2.5e-05 23.3 0.0 0.024 13.6 0.0 2.1 2 0 0 2 2 2 2 Kinase-like APH PF01636.18 KLO06099.1 - 0.00037 20.3 0.4 0.2 11.3 0.0 2.7 2 1 1 3 3 3 2 Phosphotransferase enzyme family DUF4654 PF15547.1 KLO06099.1 - 0.089 13.1 0.7 3.8 7.8 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4654) Methyltransf_2 PF00891.13 KLO06101.1 - 1.8e-31 109.2 0.0 5.3e-31 107.6 0.0 1.7 1 1 0 1 1 1 1 O-methyltransferase Methyltransf_18 PF12847.2 KLO06101.1 - 6.8e-05 23.4 0.0 0.00015 22.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KLO06101.1 - 0.027 14.1 0.0 0.08 12.6 0.0 1.8 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.7 KLO06101.1 - 0.1 13.0 0.0 0.29 11.6 0.0 1.9 1 0 0 1 1 1 0 Methyltransferase domain Ribosomal_L10 PF00466.15 KLO06104.1 - 8e-26 89.8 1.7 1.1e-25 89.3 0.2 1.9 2 0 0 2 2 2 1 Ribosomal protein L10 Ribosomal_60s PF00428.14 KLO06104.1 - 2.4e-21 75.9 10.0 1.1e-20 73.7 5.2 2.3 2 0 0 2 2 2 1 60s Acidic ribosomal protein S19 PF06756.6 KLO06104.1 - 0.034 14.0 0.9 0.05 13.4 0.0 1.7 2 0 0 2 2 2 0 Chorion protein S19 C-terminal G-alpha PF00503.15 KLO06108.1 - 4.5e-117 391.0 0.0 2.2e-116 388.7 0.0 1.8 1 1 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 KLO06108.1 - 1.5e-13 50.3 0.2 2.4e-09 36.6 0.0 2.3 2 0 0 2 2 2 2 ADP-ribosylation factor family AAA_29 PF13555.1 KLO06108.1 - 0.0053 16.2 0.0 0.013 14.9 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain GTP_EFTU PF00009.22 KLO06108.1 - 0.044 13.2 0.0 1.1 8.5 0.0 2.2 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain PHD PF00628.24 KLO06109.1 - 2.5e-08 33.4 6.9 4.5e-08 32.6 4.8 1.4 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.1 KLO06109.1 - 0.0033 16.7 5.1 0.0064 15.7 3.5 1.5 1 0 0 1 1 1 1 PHD-finger BTB PF00651.26 KLO06111.1 - 4.3e-05 23.4 0.2 0.00076 19.4 0.1 2.4 1 1 0 1 1 1 1 BTB/POZ domain DUF2905 PF11146.3 KLO06112.1 - 0.013 15.4 0.3 0.018 14.9 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2905) Aldo_ket_red PF00248.16 KLO06113.1 - 5.3e-64 215.7 0.1 6.1e-64 215.5 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family LOH1CR12 PF10158.4 KLO06113.1 - 0.033 13.9 0.1 0.065 13.0 0.0 1.5 1 0 0 1 1 1 0 Tumour suppressor protein BTB PF00651.26 KLO06114.1 - 1.9e-07 31.0 0.4 1e-06 28.6 0.0 2.1 2 0 0 2 2 2 1 BTB/POZ domain Lipase_3 PF01764.20 KLO06115.1 - 4.4e-10 39.3 0.0 6e-10 38.8 0.0 1.2 1 0 0 1 1 1 1 Lipase (class 3) BTB PF00651.26 KLO06116.1 - 4.1e-05 23.5 0.0 7.9e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain DUF3716 PF12511.3 KLO06116.1 - 0.2 11.2 3.2 0.38 10.3 2.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3716) BTB PF00651.26 KLO06118.1 - 7.8e-07 29.0 0.0 2e-06 27.7 0.0 1.7 1 0 0 1 1 1 1 BTB/POZ domain BTB PF00651.26 KLO06119.1 - 0.019 14.9 0.1 0.061 13.3 0.0 1.9 1 1 0 1 1 1 0 BTB/POZ domain BTB PF00651.26 KLO06120.1 - 0.00073 19.5 0.1 0.0038 17.1 0.0 2.2 1 1 0 1 1 1 1 BTB/POZ domain Lactonase PF10282.4 KLO06120.1 - 0.15 11.0 0.0 0.22 10.5 0.0 1.2 1 0 0 1 1 1 0 Lactonase, 7-bladed beta-propeller BTB PF00651.26 KLO06121.1 - 2e-08 34.1 0.3 6.5e-07 29.3 0.1 2.8 3 1 0 3 3 3 1 BTB/POZ domain Toxin-deaminase PF14424.1 KLO06121.1 - 0.12 12.3 0.1 0.23 11.4 0.1 1.3 1 0 0 1 1 1 0 The BURPS668_1122 family of deaminases BTB PF00651.26 KLO06122.1 - 5.2e-09 36.0 0.1 1.1e-07 31.7 0.0 2.6 2 1 0 2 2 2 1 BTB/POZ domain BTB PF00651.26 KLO06123.1 - 4.8e-08 32.9 0.5 1.1e-06 28.6 0.1 2.9 2 1 0 2 2 2 1 BTB/POZ domain Lipase_3 PF01764.20 KLO06124.1 - 1.9e-21 76.1 0.0 2.5e-21 75.7 0.0 1.1 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.2 KLO06124.1 - 0.0027 17.6 0.1 0.0034 17.2 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KLO06124.1 - 0.048 13.2 0.2 0.2 11.2 0.0 1.8 1 1 1 2 2 2 0 alpha/beta hydrolase fold Rubis-subs-bind PF09273.6 KLO06125.1 - 0.09 12.6 0.0 0.19 11.6 0.0 1.5 1 0 0 1 1 1 0 Rubisco LSMT substrate-binding F-box-like PF12937.2 KLO06126.1 - 9.4e-07 28.4 1.4 2.6e-06 27.0 0.2 2.4 3 0 0 3 3 3 1 F-box-like LRR_8 PF13855.1 KLO06126.1 - 0.055 13.2 0.5 7.5 6.3 0.1 3.9 3 1 1 4 4 4 0 Leucine rich repeat Herpes_US9 PF06072.6 KLO06130.1 - 5.6 6.8 6.2 5.4 6.9 0.4 3.1 3 0 0 3 3 3 0 Alphaherpesvirus tegument protein US9 DUF368 PF04018.8 KLO06134.1 - 0.024 13.8 6.0 0.031 13.4 3.9 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF368) Ten1_2 PF15490.1 KLO06135.1 - 0.07 12.7 0.1 5.4 6.6 0.0 2.8 1 1 2 3 3 3 0 Telomere-capping, CST complex subunit PIF1 PF05970.9 KLO06136.1 - 1.3e-09 37.5 0.0 1.4e-09 37.4 0.0 1.0 1 0 0 1 1 1 1 PIF1-like helicase Sugar_tr PF00083.19 KLO06137.1 - 2.1e-12 46.3 4.4 5.7e-10 38.3 0.9 3.4 3 1 0 3 3 3 2 Sugar (and other) transporter MFS_1 PF07690.11 KLO06137.1 - 0.00059 18.6 5.0 0.009 14.7 1.6 2.2 2 0 0 2 2 2 2 Major Facilitator Superfamily MAD PF05557.8 KLO06137.1 - 0.069 11.2 0.0 0.096 10.7 0.0 1.1 1 0 0 1 1 1 0 Mitotic checkpoint protein NOT2_3_5 PF04153.13 KLO06137.1 - 0.15 11.9 0.0 0.98 9.3 0.0 2.0 2 0 0 2 2 2 0 NOT2 / NOT3 / NOT5 family Metal_resist PF13801.1 KLO06137.1 - 0.37 10.7 2.9 0.78 9.7 0.0 2.6 3 0 0 3 3 3 0 Heavy-metal resistance Corona_5a PF06336.6 KLO06139.1 - 0.052 13.4 0.6 0.093 12.6 0.1 1.7 1 1 0 1 1 1 0 Coronavirus 5a protein Sugar_tr PF00083.19 KLO06141.1 - 1.4e-108 363.3 23.9 1.6e-108 363.1 16.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KLO06141.1 - 2.3e-22 79.2 30.5 4e-22 78.4 21.1 1.4 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF1129 PF06570.6 KLO06141.1 - 0.73 9.1 5.3 0.7 9.1 0.6 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1129) PIN_3 PF13470.1 KLO06142.1 - 0.43 11.2 7.1 1.4 9.5 0.4 2.9 2 0 0 2 2 2 0 PIN domain MIP-T3 PF10243.4 KLO06142.1 - 1.6 7.1 53.4 0.012 14.1 13.8 2.3 2 0 0 2 2 2 0 Microtubule-binding protein MIP-T3 DUF3759 PF12585.3 KLO06145.1 - 0.00013 21.8 0.2 0.0002 21.1 0.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3759) Sugar_tr PF00083.19 KLO06147.1 - 4.5e-107 358.4 20.7 5.3e-107 358.1 14.4 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KLO06147.1 - 1.4e-20 73.3 34.8 2.2e-16 59.5 8.5 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 KLO06147.1 - 0.00013 20.4 1.0 0.00013 20.4 0.7 3.6 3 1 1 4 4 4 2 MFS/sugar transport protein DUF791 PF05631.9 KLO06147.1 - 0.00044 19.0 0.3 0.00044 19.0 0.2 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF791) TRI12 PF06609.8 KLO06147.1 - 0.00074 17.8 1.2 0.0011 17.2 0.2 1.7 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Phage_holin_2 PF04550.7 KLO06147.1 - 0.13 12.3 1.4 1.1 9.4 1.0 2.3 1 1 1 2 2 2 0 Phage holin family 2 Astacin PF01400.19 KLO06148.1 - 0.00042 19.7 0.1 0.0033 16.8 0.1 2.2 1 1 0 1 1 1 1 Astacin (Peptidase family M12A) Peptidase_M10 PF00413.19 KLO06148.1 - 0.0029 17.3 0.0 0.0055 16.4 0.0 1.5 1 0 0 1 1 1 1 Matrixin DUF4131 PF13567.1 KLO06148.1 - 1 8.7 5.1 0.25 10.7 1.1 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) SGIII PF15467.1 KLO06149.1 - 0.04 12.9 0.3 0.047 12.7 0.2 1.0 1 0 0 1 1 1 0 Secretogranin-3 zf-PHD-like PF15446.1 KLO06149.1 - 0.041 13.1 3.7 0.053 12.8 2.6 1.2 1 0 0 1 1 1 0 PHD/FYVE-zinc-finger like domain Stc1 PF12898.2 KLO06149.1 - 0.049 13.6 0.7 0.049 13.6 0.5 2.2 1 1 1 2 2 2 0 Stc1 domain DZR PF12773.2 KLO06149.1 - 0.066 13.0 1.8 0.13 12.0 0.7 1.9 2 0 0 2 2 2 0 Double zinc ribbon zf-CSL PF05207.8 KLO06149.1 - 0.073 12.5 0.6 0.15 11.5 0.4 1.5 1 0 0 1 1 1 0 CSL zinc finger DUF4529 PF15032.1 KLO06149.1 - 0.099 11.2 2.7 0.12 10.9 1.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4529) FYVE PF01363.16 KLO06149.1 - 0.1 12.4 5.3 0.15 11.9 3.7 1.6 1 1 0 1 1 1 0 FYVE zinc finger SBP PF03110.9 KLO06149.1 - 0.2 11.9 2.7 1.1 9.4 1.9 2.1 1 1 0 1 1 1 0 SBP domain RNA_POL_M_15KD PF02150.11 KLO06149.1 - 0.21 11.2 1.8 7.8 6.2 0.1 2.6 2 0 0 2 2 2 0 RNA polymerases M/15 Kd subunit ThiF PF00899.16 KLO06151.1 - 2.6e-38 130.8 0.0 4.4e-38 130.1 0.0 1.3 1 0 0 1 1 1 1 ThiF family UBACT PF02134.16 KLO06151.1 - 1.4e-28 98.2 0.3 2.9e-28 97.2 0.2 1.6 1 0 0 1 1 1 1 Repeat in ubiquitin-activating (UBA) protein UBA_e1_thiolCys PF10585.4 KLO06151.1 - 5.6e-20 70.4 1.1 1.3e-19 69.2 0.7 1.7 1 0 0 1 1 1 1 Ubiquitin-activating enzyme active site UAE_UbL PF14732.1 KLO06151.1 - 1.4e-07 31.5 0.0 3e-07 30.4 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin/SUMO-activating enzyme ubiquitin-like domain NAD_binding_7 PF13241.1 KLO06151.1 - 0.023 14.9 0.0 0.1 12.8 0.0 2.1 2 1 0 2 2 2 0 Putative NAD(P)-binding CPL PF08144.6 KLO06152.1 - 3.1e-25 88.7 1.8 6.2e-23 81.2 0.0 3.6 3 1 0 3 3 3 2 CPL (NUC119) domain WD40 PF00400.27 KLO06156.1 - 3.4e-10 39.3 1.0 1.6e-06 27.7 0.1 3.5 3 0 0 3 3 3 2 WD domain, G-beta repeat OpuAC PF04069.7 KLO06156.1 - 0.17 11.1 0.0 0.62 9.3 0.0 1.7 2 0 0 2 2 2 0 Substrate binding domain of ABC-type glycine betaine transport system DUF2201_N PF13203.1 KLO06158.1 - 0.15 11.1 1.5 0.22 10.6 1.0 1.2 1 0 0 1 1 1 0 Putative metallopeptidase domain Sad1_UNC PF07738.8 KLO06159.1 - 1.4e-24 86.3 0.0 7.8e-12 45.1 0.0 2.1 1 1 1 2 2 2 2 Sad1 / UNC-like C-terminal Bin3 PF06859.7 KLO06162.1 - 0.13 12.2 0.0 0.18 11.8 0.0 1.3 1 0 0 1 1 1 0 Bicoid-interacting protein 3 (Bin3) F-box PF00646.28 KLO06163.1 - 0.0022 17.5 0.0 0.014 15.0 0.0 2.2 2 0 0 2 2 2 1 F-box domain Thg1 PF04446.7 KLO06163.1 - 0.08 12.5 0.1 0.46 10.1 0.0 2.2 2 0 0 2 2 2 0 tRNAHis guanylyltransferase F-box-like PF12937.2 KLO06163.1 - 0.11 12.2 0.0 0.29 10.9 0.0 1.6 1 0 0 1 1 1 0 F-box-like Baculo_PEP_C PF04513.7 KLO06165.1 - 2.2e-06 27.5 24.0 0.74 9.6 0.4 7.9 4 3 4 9 9 9 4 Baculovirus polyhedron envelope protein, PEP, C terminus DUF948 PF06103.6 KLO06165.1 - 0.0027 17.5 14.3 0.47 10.3 0.0 6.7 6 1 1 7 7 7 2 Bacterial protein of unknown function (DUF948) TBPIP PF07106.8 KLO06165.1 - 0.027 14.0 20.7 0.073 12.6 0.0 5.4 4 2 1 5 5 5 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) HSBP1 PF06825.7 KLO06165.1 - 0.03 13.9 6.2 1.6 8.3 0.3 4.2 4 0 0 4 4 4 0 Heat shock factor binding protein 1 KxDL PF10241.4 KLO06165.1 - 0.045 13.6 7.1 4.4 7.2 0.2 4.5 4 0 0 4 4 4 0 Uncharacterized conserved protein DELLA PF12041.3 KLO06165.1 - 0.058 13.0 2.8 0.1 12.2 0.2 2.8 2 0 0 2 2 2 0 Transcriptional regulator DELLA protein N terminal Bacillus_HBL PF05791.6 KLO06165.1 - 0.1 11.9 0.0 0.1 11.9 0.0 3.4 4 1 0 4 4 4 0 Bacillus haemolytic enterotoxin (HBL) DUF148 PF02520.12 KLO06165.1 - 1.8 8.3 15.8 0.41 10.4 0.3 5.4 3 1 2 6 6 6 0 Domain of unknown function DUF148 DUF1664 PF07889.7 KLO06165.1 - 5.4 6.8 30.2 1.1 9.0 0.3 6.9 6 2 2 8 8 8 0 Protein of unknown function (DUF1664) RHH_1 PF01402.16 KLO06165.1 - 7.6 6.6 10.1 15 5.7 0.1 4.4 5 0 0 5 5 5 0 Ribbon-helix-helix protein, copG family DUF16 PF01519.11 KLO06165.1 - 9 6.5 19.4 0.88 9.8 0.3 5.5 2 1 2 4 4 3 0 Protein of unknown function DUF16 DEAD PF00270.24 KLO06167.1 - 2.1e-18 66.3 0.0 1.6e-17 63.4 0.0 2.2 3 0 0 3 3 3 1 DEAD/DEAH box helicase PrgH PF09480.5 KLO06167.1 - 0.0046 15.8 0.0 0.14 11.0 0.0 2.0 1 1 0 2 2 2 1 Type III secretion system protein PrgH-EprH (PrgH) SecA_DEAD PF07517.9 KLO06167.1 - 0.059 12.6 0.0 0.11 11.7 0.0 1.4 1 0 0 1 1 1 0 SecA DEAD-like domain Helicase_C PF00271.26 KLO06167.1 - 0.06 13.2 0.0 0.17 11.7 0.0 1.7 1 0 0 1 1 1 0 Helicase conserved C-terminal domain zf-C2H2_4 PF13894.1 KLO06168.1 - 8.3e-06 25.7 12.0 0.061 13.6 0.4 3.5 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2 PF00096.21 KLO06168.1 - 1.3e-05 25.2 12.0 0.0095 16.2 0.5 3.5 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 KLO06168.1 - 0.0049 17.0 12.9 1.4 9.3 0.2 3.5 3 0 0 3 3 3 2 Zinc-finger double domain zinc_ribbon_5 PF13719.1 KLO06168.1 - 0.015 14.8 0.9 0.028 13.9 0.6 1.4 1 0 0 1 1 1 0 zinc-ribbon domain zinc_ribbon_4 PF13717.1 KLO06168.1 - 0.023 14.3 1.2 0.044 13.4 0.8 1.4 1 0 0 1 1 1 0 zinc-ribbon domain Med15 PF09606.5 KLO06168.1 - 0.097 10.8 3.5 0.12 10.5 2.4 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal zf-BED PF02892.10 KLO06168.1 - 6.1 6.6 10.2 1.2 8.9 1.6 2.8 3 0 0 3 3 3 0 BED zinc finger WD40 PF00400.27 KLO06169.1 - 8.8e-41 136.3 31.1 1.5e-08 34.2 0.1 8.0 8 0 0 8 8 7 7 WD domain, G-beta repeat AAA_22 PF13401.1 KLO06169.1 - 1.7e-11 44.3 0.0 2.8e-05 24.2 0.0 3.6 3 0 0 3 3 3 2 AAA domain AAA_16 PF13191.1 KLO06169.1 - 8e-10 39.0 1.5 0.0014 18.6 0.0 3.4 3 0 0 3 3 3 2 AAA ATPase domain NACHT PF05729.7 KLO06169.1 - 1.8e-08 34.2 8.9 0.0089 15.6 0.0 4.9 4 1 0 4 4 4 3 NACHT domain AAA PF00004.24 KLO06169.1 - 2.7e-08 34.0 0.0 0.0012 19.0 0.0 3.2 2 1 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) NB-ARC PF00931.17 KLO06169.1 - 4.8e-08 32.2 0.2 0.0031 16.4 0.0 3.1 3 1 0 3 3 3 2 NB-ARC domain AAA_18 PF13238.1 KLO06169.1 - 6e-08 33.0 0.0 0.0018 18.5 0.0 3.4 3 0 0 3 3 3 2 AAA domain AAA_17 PF13207.1 KLO06169.1 - 2e-07 31.8 1.4 0.04 14.7 0.0 4.1 4 1 0 4 4 2 2 AAA domain AAA_33 PF13671.1 KLO06169.1 - 4.3e-07 29.9 0.0 0.035 13.9 0.0 3.0 2 0 0 2 2 2 2 AAA domain AAA_14 PF13173.1 KLO06169.1 - 1.2e-05 25.1 0.1 0.22 11.4 0.0 4.0 4 0 0 4 4 4 2 AAA domain RNA_helicase PF00910.17 KLO06169.1 - 3.6e-05 23.8 0.0 0.5 10.5 0.0 3.0 2 0 0 2 2 2 2 RNA helicase Viral_helicase1 PF01443.13 KLO06169.1 - 5.7e-05 22.7 0.0 0.24 10.8 0.0 2.6 2 0 0 2 2 2 2 Viral (Superfamily 1) RNA helicase Zeta_toxin PF06414.7 KLO06169.1 - 6.7e-05 22.0 0.0 0.21 10.6 0.0 2.6 2 0 0 2 2 2 2 Zeta toxin ABC_tran PF00005.22 KLO06169.1 - 7e-05 23.1 0.1 0.34 11.1 0.0 3.1 3 0 0 3 3 2 2 ABC transporter DUF2075 PF09848.4 KLO06169.1 - 8e-05 21.7 0.0 0.058 12.3 0.0 2.9 3 0 0 3 3 3 1 Uncharacterized conserved protein (DUF2075) AAA_25 PF13481.1 KLO06169.1 - 0.00011 21.6 0.5 0.69 9.2 0.0 3.2 2 1 0 2 2 2 2 AAA domain MMR_HSR1 PF01926.18 KLO06169.1 - 0.00042 20.2 0.0 1.2 9.1 0.0 3.7 3 1 0 3 3 2 1 50S ribosome-binding GTPase APS_kinase PF01583.15 KLO06169.1 - 0.00062 19.4 1.0 1 9.0 0.1 3.4 3 0 0 3 3 3 1 Adenylylsulphate kinase AAA_19 PF13245.1 KLO06169.1 - 0.00076 19.1 0.1 1.1 9.0 0.1 2.8 2 0 0 2 2 2 1 Part of AAA domain FtsK_SpoIIIE PF01580.13 KLO06169.1 - 0.00091 18.7 0.0 1.4 8.3 0.0 2.6 2 0 0 2 2 2 2 FtsK/SpoIIIE family AAA_28 PF13521.1 KLO06169.1 - 0.0029 17.6 0.1 3.7 7.4 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.1 KLO06169.1 - 0.0029 17.0 0.1 3.6 7.1 0.0 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_24 PF13479.1 KLO06169.1 - 0.0038 16.8 0.1 2.3 7.7 0.0 2.8 2 0 0 2 2 2 1 AAA domain ADK PF00406.17 KLO06169.1 - 0.0045 16.8 0.7 5.2 6.9 0.1 3.7 3 0 0 3 3 3 0 Adenylate kinase Hira PF07569.6 KLO06169.1 - 0.019 14.1 0.1 0.19 10.9 0.0 2.5 2 0 0 2 2 2 0 TUP1-like enhancer of split ArgK PF03308.11 KLO06169.1 - 0.024 13.3 0.2 5 5.8 0.0 2.9 3 0 0 3 3 3 0 ArgK protein DUF258 PF03193.11 KLO06169.1 - 0.028 13.6 0.0 6.4 5.9 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function, DUF258 AAA_30 PF13604.1 KLO06169.1 - 0.039 13.5 0.3 4.8 6.7 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.9 KLO06169.1 - 0.05 13.3 0.1 14 5.3 0.0 2.7 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_11 PF13086.1 KLO06169.1 - 0.056 13.0 0.0 20 4.6 0.0 3.1 2 1 0 2 2 2 0 AAA domain PD40 PF07676.7 KLO06169.1 - 0.062 12.9 0.2 2.4 7.8 0.0 2.9 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat Torsin PF06309.6 KLO06169.1 - 0.071 12.9 0.0 6.8 6.5 0.0 2.7 2 0 0 2 2 2 0 Torsin MobB PF03205.9 KLO06169.1 - 0.073 12.7 1.4 8.6 6.0 0.1 2.6 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B Mg_chelatase PF01078.16 KLO06169.1 - 0.18 10.9 0.2 19 4.3 0.0 2.5 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_10 PF12846.2 KLO06169.1 - 1 8.6 7.4 11 5.2 0.0 4.4 5 1 0 6 6 6 0 AAA-like domain CcoS PF03597.10 KLO06170.1 - 0.037 13.4 0.2 0.037 13.4 0.1 2.7 3 0 0 3 3 3 0 Cytochrome oxidase maturation protein cbb3-type SKG6 PF08693.5 KLO06171.1 - 0.00025 20.3 0.4 0.0013 17.9 0.3 2.2 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Adeno_E3_CR2 PF02439.10 KLO06171.1 - 0.0056 16.1 0.0 0.012 15.1 0.0 1.5 1 0 0 1 1 1 1 Adenovirus E3 region protein CR2 DUF4328 PF14219.1 KLO06171.1 - 0.006 15.8 0.0 0.011 15.0 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4328) EphA2_TM PF14575.1 KLO06171.1 - 0.024 15.0 0.0 0.073 13.4 0.0 1.8 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain ATG22 PF11700.3 KLO06171.1 - 0.034 12.6 2.6 0.049 12.0 1.8 1.2 1 0 0 1 1 1 0 Vacuole effluxer Atg22 like Syndecan PF01034.15 KLO06171.1 - 0.061 12.9 0.8 0.097 12.3 0.0 1.7 2 0 0 2 2 2 0 Syndecan domain Rifin_STEVOR PF02009.11 KLO06171.1 - 0.091 12.3 4.2 0.16 11.5 2.5 1.6 1 1 0 1 1 1 0 Rifin/stevor family SKG6 PF08693.5 KLO06173.1 - 0.0057 15.9 0.2 0.015 14.5 0.1 1.7 1 0 0 1 1 1 1 Transmembrane alpha-helix domain GTP_CH_N PF12471.3 KLO06174.1 - 7.4e-87 290.0 0.0 1e-86 289.5 0.0 1.2 1 0 0 1 1 1 1 GTP cyclohydrolase N terminal GTP_cyclohydro2 PF00925.15 KLO06174.1 - 2.9e-14 52.6 0.0 4.4e-14 52.0 0.0 1.2 1 0 0 1 1 1 1 GTP cyclohydrolase II Pex14_N PF04695.8 KLO06176.1 - 0.0059 16.6 1.3 0.016 15.2 0.9 1.7 1 0 0 1 1 1 1 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF1517 PF07466.6 KLO06176.1 - 0.065 12.2 1.9 0.1 11.5 1.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1517) Plasmodium_Vir PF05795.6 KLO06176.1 - 0.13 11.4 0.2 0.18 11.0 0.1 1.2 1 0 0 1 1 1 0 Plasmodium vivax Vir protein MRI PF15325.1 KLO06176.1 - 7.7 7.5 10.3 18 6.3 7.2 1.6 1 0 0 1 1 1 0 Modulator of retrovirus infection Fungal_trans PF04082.13 KLO06178.1 - 4.4e-10 38.8 0.0 1e-09 37.6 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KLO06178.1 - 2.8e-07 30.3 10.1 5.4e-07 29.4 7.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HALZ PF02183.13 KLO06178.1 - 0.008 15.8 0.4 0.016 14.9 0.3 1.5 1 0 0 1 1 1 1 Homeobox associated leucine zipper PIRT PF15099.1 KLO06180.1 - 0.091 11.9 0.2 2.6 7.2 0.0 2.7 2 1 1 3 3 3 0 Phosphoinositide-interacting protein family Macscav_rec PF03523.8 KLO06182.1 - 0.005 16.5 0.0 1.3 8.8 0.0 2.5 2 0 0 2 2 2 2 Macrophage scavenger receptor BTB PF00651.26 KLO06185.1 - 0.0039 17.1 0.0 0.0078 16.1 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain Topo-VIb_trans PF09239.6 KLO06187.1 - 0.031 13.7 0.0 0.045 13.2 0.0 1.2 1 0 0 1 1 1 0 Topoisomerase VI B subunit, transducer Rtt106 PF08512.7 KLO06187.1 - 0.12 12.3 0.1 0.21 11.6 0.0 1.4 1 1 0 1 1 1 0 Histone chaperone Rttp106-like Zn_clus PF00172.13 KLO06189.1 - 5.7e-06 26.1 12.3 5.7e-06 26.1 8.5 2.0 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-MYND PF01753.13 KLO06191.1 - 1.2e-07 31.4 13.4 1.2e-07 31.4 9.3 1.8 2 0 0 2 2 2 1 MYND finger Cpn10 PF00166.16 KLO06192.1 - 7.3e-26 89.9 0.0 8.4e-26 89.7 0.0 1.0 1 0 0 1 1 1 1 Chaperonin 10 Kd subunit zf-MYND PF01753.13 KLO06195.1 - 0.1 12.5 13.0 0.24 11.3 9.0 1.7 1 0 0 1 1 1 0 MYND finger DUF2256 PF10013.4 KLO06195.1 - 0.43 10.3 6.6 1.9 8.2 4.5 2.1 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2256) F-box-like PF12937.2 KLO06196.1 - 0.00081 19.0 0.0 0.0031 17.2 0.0 2.0 1 0 0 1 1 1 1 F-box-like LRR_8 PF13855.1 KLO06196.1 - 0.15 11.8 7.6 3 7.6 0.0 3.6 3 0 0 3 3 3 0 Leucine rich repeat zf-MYND PF01753.13 KLO06197.1 - 0.00012 21.8 15.4 0.00034 20.4 10.7 1.8 1 0 0 1 1 1 1 MYND finger F-box-like PF12937.2 KLO06198.1 - 2.4e-05 23.9 0.0 8.9e-05 22.1 0.0 2.1 2 0 0 2 2 2 1 F-box-like Abhydrolase_6 PF12697.2 KLO06199.1 - 2.4e-21 76.6 0.0 2.9e-21 76.4 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KLO06199.1 - 1e-06 28.5 0.0 1.5e-06 28.0 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KLO06199.1 - 1.1e-05 25.0 0.0 1.4e-05 24.7 0.0 1.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.3 KLO06199.1 - 0.001 18.8 0.0 0.002 17.9 0.0 1.5 1 0 0 1 1 1 1 Putative lysophospholipase CcoS PF03597.10 KLO06200.1 - 0.26 10.7 2.4 1.2 8.7 1.6 2.2 1 0 0 1 1 1 0 Cytochrome oxidase maturation protein cbb3-type Tweety PF04906.8 KLO06200.1 - 0.9 7.8 3.0 1.4 7.2 2.1 1.2 1 0 0 1 1 1 0 Tweety 2TM PF13239.1 KLO06200.1 - 1.3 9.1 8.8 0.5 10.4 0.4 3.0 3 0 0 3 3 3 0 2TM domain F-box-like PF12937.2 KLO06201.1 - 2.8e-05 23.7 2.1 8e-05 22.2 1.4 1.8 1 0 0 1 1 1 1 F-box-like CRISPR_Cse1 PF09481.5 KLO06203.1 - 0.045 12.5 0.0 0.049 12.3 0.0 1.0 1 0 0 1 1 1 0 CRISPR-associated protein Cse1 (CRISPR_cse1) F-box-like PF12937.2 KLO06205.1 - 2.6e-07 30.2 2.5 5.1e-05 22.9 0.1 3.7 3 0 0 3 3 3 1 F-box-like F-box PF00646.28 KLO06205.1 - 9.8 5.9 9.1 1.5 8.6 0.7 3.6 3 1 0 3 3 3 0 F-box domain Helicase_C PF00271.26 KLO06209.1 - 9.8e-16 57.3 0.0 3e-15 55.8 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 KLO06209.1 - 4.1e-14 52.4 0.0 7.8e-14 51.5 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.10 KLO06209.1 - 4.5e-06 26.6 0.0 1.1e-05 25.3 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit F-box-like PF12937.2 KLO06210.1 - 0.0012 18.4 0.0 0.0053 16.4 0.0 2.1 1 0 0 1 1 1 1 F-box-like LRR_8 PF13855.1 KLO06210.1 - 0.0043 16.7 0.1 0.17 11.6 0.0 3.5 3 1 0 3 3 3 1 Leucine rich repeat F-box-like PF12937.2 KLO06211.1 - 0.00024 20.7 0.1 0.00092 18.8 0.1 2.0 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KLO06211.1 - 0.012 15.2 0.4 0.012 15.2 0.3 3.1 3 0 0 3 3 3 0 F-box domain DUF1241 PF06840.6 KLO06212.1 - 0.025 13.8 0.7 0.033 13.4 0.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1241) DUF972 PF06156.8 KLO06212.1 - 0.055 13.8 3.8 0.039 14.3 1.5 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF972) Bap31 PF05529.7 KLO06212.1 - 0.079 12.4 2.7 0.11 11.9 1.9 1.4 1 1 0 1 1 1 0 B-cell receptor-associated protein 31-like Cob_adeno_trans PF01923.13 KLO06212.1 - 0.081 12.7 0.1 0.11 12.3 0.1 1.1 1 0 0 1 1 1 0 Cobalamin adenosyltransferase CorA PF01544.13 KLO06212.1 - 0.094 11.7 0.2 0.12 11.3 0.1 1.1 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein Syntaxin-6_N PF09177.6 KLO06212.1 - 0.21 12.0 2.8 0.66 10.4 2.0 2.0 1 1 0 1 1 1 0 Syntaxin 6, N-terminal HALZ PF02183.13 KLO06212.1 - 0.87 9.3 4.1 7.1 6.4 0.4 2.3 2 0 0 2 2 2 0 Homeobox associated leucine zipper DMPK_coil PF08826.5 KLO06212.1 - 1.2 9.0 4.9 10 6.1 1.5 2.3 1 1 1 2 2 2 0 DMPK coiled coil domain like DUF241 PF03087.9 KLO06213.1 - 0.023 14.2 0.7 0.03 13.8 0.5 1.1 1 0 0 1 1 1 0 Arabidopsis protein of unknown function DDE_Tnp_4 PF13359.1 KLO06216.1 - 0.0012 18.4 0.1 0.0022 17.5 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease Spt5_N PF11942.3 KLO06216.1 - 0.064 13.8 7.1 0.16 12.6 4.9 1.6 1 1 0 1 1 1 0 Spt5 transcription elongation factor, acidic N-terminal DDE_Tnp_4 PF13359.1 KLO06217.1 - 3.7e-15 55.8 0.0 7.3e-15 54.9 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease MRP-S27 PF10037.4 KLO06217.1 - 0.066 12.1 0.1 0.13 11.1 0.1 1.4 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S27 DUF3787 PF12655.2 KLO06217.1 - 0.11 12.2 0.5 0.79 9.4 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3787) zf-RVT PF13966.1 KLO06219.1 - 0.00019 21.6 0.1 0.0004 20.6 0.0 1.5 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase DUF1593 PF07632.6 KLO06220.1 - 0.0028 16.9 0.0 0.0055 16.0 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1593) DUF605 PF04652.11 KLO06222.1 - 5.6 6.2 12.5 8 5.7 8.7 1.3 1 0 0 1 1 1 0 Vta1 like KOW PF00467.24 KLO06223.1 - 3.9e-13 48.5 12.9 0.0036 16.9 0.1 6.4 6 0 0 6 6 6 5 KOW motif Spt5-NGN PF03439.8 KLO06223.1 - 1.9e-08 33.9 0.0 3.7e-08 32.9 0.0 1.4 1 0 0 1 1 1 1 Early transcription elongation factor of RNA pol II, NGN section FGGY_N PF00370.16 KLO06227.1 - 0.11 11.8 0.0 0.11 11.8 0.0 1.1 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, N-terminal domain DUF1212 PF06738.7 KLO06228.1 - 8.4e-29 100.4 7.4 9.8e-26 90.4 0.1 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF1212) DUF3815 PF12821.2 KLO06228.1 - 3.7e-15 55.9 34.7 1.4e-14 54.1 7.8 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF3815) DUF1212 PF06738.7 KLO06229.1 - 3.7e-24 85.2 0.3 3.7e-24 85.2 0.2 3.1 3 0 0 3 3 3 2 Protein of unknown function (DUF1212) DUF3815 PF12821.2 KLO06229.1 - 7.7e-10 38.8 10.4 7.7e-10 38.8 7.2 2.9 3 0 0 3 3 3 1 Protein of unknown function (DUF3815) PIRT PF15099.1 KLO06229.1 - 0.00072 18.7 1.4 0.0014 17.8 0.5 1.8 1 1 0 1 1 1 1 Phosphoinositide-interacting protein family Pkinase PF00069.20 KLO06230.1 - 2.7e-31 108.6 0.0 3.1e-31 108.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KLO06230.1 - 5.3e-11 42.0 0.0 6.9e-11 41.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KLO06230.1 - 0.065 12.1 0.0 0.2 10.5 0.0 1.7 3 0 0 3 3 3 0 Kinase-like MRG PF05712.8 KLO06231.1 - 1.7e-50 170.6 0.2 2.6e-50 170.0 0.1 1.2 1 0 0 1 1 1 1 MRG Tudor-knot PF11717.3 KLO06231.1 - 9.4e-10 38.0 1.2 1.3e-09 37.6 0.2 1.8 2 0 0 2 2 2 1 RNA binding activity-knot of a chromodomain Chromo PF00385.19 KLO06231.1 - 0.044 13.4 1.1 0.11 12.2 0.8 1.6 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain Mago_nashi PF02792.9 KLO06233.1 - 3.9e-74 247.0 0.6 4.4e-74 246.9 0.4 1.0 1 0 0 1 1 1 1 Mago nashi protein SurE PF01975.12 KLO06234.1 - 1e-33 116.3 0.7 1.9e-33 115.4 0.5 1.4 1 0 0 1 1 1 1 Survival protein SurE p450 PF00067.17 KLO06235.1 - 2.9e-24 85.4 0.0 3.7e-24 85.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Lipase_3 PF01764.20 KLO06236.1 - 1.1e-15 57.5 0.0 2.3e-15 56.4 0.0 1.5 1 0 0 1 1 1 1 Lipase (class 3) DUF2305 PF10230.4 KLO06236.1 - 0.059 12.7 0.2 7.9 5.8 0.0 2.3 2 0 0 2 2 2 0 Uncharacterised conserved protein (DUF2305) p450 PF00067.17 KLO06237.1 - 7.5e-68 229.1 0.0 9.4e-68 228.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Hyccin PF09790.4 KLO06237.1 - 0.17 10.7 0.0 0.32 9.8 0.0 1.4 1 0 0 1 1 1 0 Hyccin GldM_C PF12080.3 KLO06240.1 - 0.043 13.7 0.0 0.063 13.2 0.0 1.2 1 0 0 1 1 1 0 GldM C-terminal domain FAM163 PF15069.1 KLO06240.1 - 0.62 10.6 5.0 1.2 9.7 3.4 1.5 1 1 0 1 1 1 0 FAM163 family Pil1 PF13805.1 KLO06243.1 - 1.8e-08 33.9 0.0 1.9e-08 33.7 0.0 1.0 1 0 0 1 1 1 1 Eisosome component PIL1 DUF4646 PF15496.1 KLO06244.1 - 1.4e-12 47.7 1.2 9.7e-10 38.5 0.0 2.4 1 1 1 2 2 2 2 Domain of unknown function (DUF4646) GLE1 PF07817.8 KLO06245.1 - 4.9e-25 87.9 1.9 7.5e-25 87.3 0.0 2.2 2 1 0 2 2 2 1 GLE1-like protein Ycf1 PF05758.7 KLO06245.1 - 0.3 8.7 6.1 0.35 8.5 4.3 1.1 1 0 0 1 1 1 0 Ycf1 Macoilin PF09726.4 KLO06245.1 - 1.4 7.0 28.1 2 6.6 19.5 1.1 1 0 0 1 1 1 0 Transmembrane protein CAF-1_p150 PF11600.3 KLO06245.1 - 2.4 7.4 48.9 3.9 6.8 33.9 1.3 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Glyco_hydro_10 PF00331.15 KLO06247.1 - 7.7e-93 311.0 0.1 8.7e-93 310.8 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 CBM_1 PF00734.13 KLO06247.1 - 7.1e-14 51.1 10.6 2.7e-13 49.3 7.4 2.1 1 0 0 1 1 1 1 Fungal cellulose binding domain Sec61_beta PF03911.11 KLO06248.1 - 4.1e-18 64.8 0.3 5.2e-18 64.5 0.2 1.1 1 0 0 1 1 1 1 Sec61beta family Synaptobrevin PF00957.16 KLO06249.1 - 1.3e-28 98.4 0.1 1.8e-28 97.9 0.1 1.2 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.1 KLO06249.1 - 6.9e-23 79.9 0.0 1.7e-22 78.7 0.0 1.6 2 0 0 2 2 2 1 Regulated-SNARE-like domain DUF1664 PF07889.7 KLO06252.1 - 0.022 14.5 1.7 0.032 14.0 1.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) DUF724 PF05266.9 KLO06252.1 - 0.027 14.0 1.7 0.044 13.4 1.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF724) Prp19 PF08606.6 KLO06252.1 - 0.083 12.6 3.7 0.16 11.6 0.4 2.4 2 0 0 2 2 2 0 Prp19/Pso4-like DUF4164 PF13747.1 KLO06252.1 - 0.11 12.6 7.5 0.2 11.8 5.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4164) FemAB PF02388.11 KLO06252.1 - 0.27 9.8 3.7 0.36 9.4 2.5 1.1 1 0 0 1 1 1 0 FemAB family IncA PF04156.9 KLO06252.1 - 2 8.0 8.2 0.41 10.2 3.0 1.7 2 0 0 2 2 2 0 IncA protein DEAD PF00270.24 KLO06253.1 - 2.3e-16 59.7 0.0 4.2e-16 58.9 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KLO06253.1 - 1.2e-15 57.0 0.0 2.7e-15 56.0 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 KLO06253.1 - 6.5e-05 22.8 0.1 0.00017 21.4 0.0 1.6 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit SNF2_N PF00176.18 KLO06253.1 - 7.1e-05 21.7 0.0 0.00012 20.9 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Rotavirus_VP1 PF12289.3 KLO06253.1 - 0.006 16.1 0.0 0.014 14.9 0.0 1.6 1 0 0 1 1 1 1 Rotavirus VP1 structural protein BTB PF00651.26 KLO06255.1 - 0.0015 18.4 0.3 0.0044 16.9 0.1 1.9 1 1 1 2 2 2 1 BTB/POZ domain BTB PF00651.26 KLO06256.1 - 7.2e-06 25.9 0.0 1.4e-05 24.9 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain BTB PF00651.26 KLO06257.1 - 0.00018 21.4 0.0 0.00057 19.8 0.0 1.8 1 1 0 1 1 1 1 BTB/POZ domain PucR PF07905.6 KLO06257.1 - 0.025 14.1 0.0 0.084 12.4 0.0 1.9 2 0 0 2 2 2 0 Purine catabolism regulatory protein-like family BTB PF00651.26 KLO06258.1 - 9.3e-06 25.6 0.0 3.7e-05 23.6 0.0 2.0 2 1 0 2 2 2 1 BTB/POZ domain BTB PF00651.26 KLO06259.1 - 0.00036 20.5 0.0 0.0013 18.7 0.0 1.9 2 1 0 2 2 2 1 BTB/POZ domain DUF4473 PF14747.1 KLO06262.1 - 0.076 13.2 0.0 0.15 12.2 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4473) NST1 PF13945.1 KLO06263.1 - 0.029 14.4 0.3 0.045 13.8 0.2 1.3 1 0 0 1 1 1 0 Salt tolerance down-regulator DAO PF01266.19 KLO06265.1 - 3.4e-30 105.1 0.0 4.9e-30 104.6 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase PSS PF03034.10 KLO06267.1 - 3.7e-100 334.9 14.0 4.9e-100 334.5 9.7 1.1 1 0 0 1 1 1 1 Phosphatidyl serine synthase Claudin_3 PF06653.6 KLO06267.1 - 0.018 14.7 0.3 0.55 9.9 0.1 2.9 3 0 0 3 3 3 0 Tight junction protein, Claudin-like DUF3918 PF13056.1 KLO06267.1 - 0.058 12.7 0.0 0.7 9.2 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3918) Zn_clus PF00172.13 KLO06269.1 - 1.1e-08 34.8 7.3 2.3e-08 33.8 5.0 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF3006 PF11213.3 KLO06269.1 - 0.053 13.2 0.2 0.22 11.2 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3006) NRDE PF05742.7 KLO06270.1 - 1.3e-33 116.4 0.0 2.8e-16 59.6 0.0 3.4 3 0 0 3 3 3 3 NRDE protein Chlam_PMP PF02415.12 KLO06270.1 - 2.7 8.4 5.9 4.6 7.7 0.0 3.1 3 0 0 3 3 3 0 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat Actin PF00022.14 KLO06271.1 - 5.8e-81 271.9 0.0 7.5e-81 271.5 0.0 1.1 1 0 0 1 1 1 1 Actin IBN_N PF03810.14 KLO06273.1 - 1.9e-13 50.1 0.1 3.6e-11 42.7 0.0 2.8 2 0 0 2 2 2 1 Importin-beta N-terminal domain DUF2435 PF10363.4 KLO06273.1 - 0.00069 19.4 0.4 0.003 17.4 0.3 2.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2435) Cse1 PF08506.5 KLO06273.1 - 0.0013 17.3 0.1 0.005 15.4 0.0 2.1 2 0 0 2 2 2 1 Cse1 HEAT PF02985.17 KLO06273.1 - 0.0024 17.8 0.1 0.16 12.1 0.0 3.7 3 0 0 3 3 3 1 HEAT repeat HEAT_2 PF13646.1 KLO06273.1 - 0.0026 18.0 4.1 0.055 13.7 0.5 4.4 3 2 1 4 4 4 1 HEAT repeats MutL_C PF08676.6 KLO06273.1 - 0.017 14.6 0.0 0.069 12.7 0.0 2.0 1 0 0 1 1 1 0 MutL C terminal dimerisation domain DUF2457 PF10446.4 KLO06273.1 - 0.2 10.3 11.6 0.31 9.7 8.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) LIN37 PF15306.1 KLO06279.1 - 0.05 13.5 1.0 0.062 13.2 0.7 1.2 1 0 0 1 1 1 0 LIN37 zf-C2H2 PF00096.21 KLO06280.1 - 1.5e-08 34.4 9.3 4.3e-06 26.7 1.1 2.1 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 KLO06280.1 - 5.7e-08 32.6 14.2 1.7e-05 24.8 3.4 2.1 2 0 0 2 2 2 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 KLO06280.1 - 0.00039 20.5 10.9 0.0025 17.9 1.6 2.1 2 0 0 2 2 2 2 C2H2-type zinc finger zf-met PF12874.2 KLO06280.1 - 0.019 15.1 3.4 0.094 12.9 0.2 2.4 2 1 0 2 2 2 0 Zinc-finger of C2H2 type IBR PF01485.16 KLO06280.1 - 0.082 12.7 4.7 0.3 10.9 0.5 2.0 1 1 1 2 2 2 0 IBR domain zf-Dof PF02701.10 KLO06280.1 - 0.12 12.3 0.3 0.12 12.3 0.2 1.4 1 1 0 1 1 1 0 Dof domain, zinc finger Rad50_zn_hook PF04423.9 KLO06280.1 - 0.15 11.5 2.7 0.22 11.0 0.1 2.1 2 0 0 2 2 2 0 Rad50 zinc hook motif DUF2225 PF09986.4 KLO06280.1 - 0.23 10.8 1.9 0.24 10.8 1.3 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2225) zf-Di19 PF05605.7 KLO06280.1 - 0.39 10.8 5.9 0.61 10.2 4.1 1.5 1 1 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf-AN1 PF01428.11 KLO06280.1 - 0.89 9.4 5.8 8.4 6.3 0.3 2.9 2 1 1 3 3 3 0 AN1-like Zinc finger zf-C2H2_jaz PF12171.3 KLO06280.1 - 1.4 9.1 4.3 0.24 11.6 0.3 1.9 2 1 0 2 2 2 0 Zinc-finger double-stranded RNA-binding SNF2_N PF00176.18 KLO06282.1 - 1.6e-08 33.7 0.1 3.5e-08 32.5 0.0 1.6 2 0 0 2 2 2 1 SNF2 family N-terminal domain Rad17 PF03215.10 KLO06284.1 - 0.021 13.5 0.0 0.038 12.6 0.0 1.3 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein CTD_bind PF04818.8 KLO06285.1 - 0.0013 18.9 0.1 1.4 9.1 0.0 2.2 2 0 0 2 2 2 2 RNA polymerase II-binding domain. FtsH_ext PF06480.10 KLO06285.1 - 0.029 14.5 0.1 0.046 13.8 0.0 1.3 1 0 0 1 1 1 0 FtsH Extracellular SLIDE PF09111.5 KLO06285.1 - 0.058 13.1 0.1 0.1 12.3 0.0 1.5 1 1 0 1 1 1 0 SLIDE zinc_ribbon_5 PF13719.1 KLO06288.1 - 0.023 14.2 0.2 0.061 12.9 0.1 1.8 1 0 0 1 1 1 0 zinc-ribbon domain zinc_ribbon_4 PF13717.1 KLO06288.1 - 0.029 14.0 0.2 0.08 12.6 0.1 1.8 1 0 0 1 1 1 0 zinc-ribbon domain DUF4218 PF13960.1 KLO06289.1 - 1.5e-06 27.6 0.1 2.1e-06 27.1 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4218) DUF1435 PF07256.7 KLO06289.1 - 0.12 12.3 0.0 0.2 11.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1435) Peptidase_C48 PF02902.14 KLO06290.1 - 0.00018 21.2 0.0 0.00018 21.2 0.0 1.1 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain Sad1_UNC PF07738.8 KLO06294.1 - 7.9e-26 90.4 0.0 9.7e-26 90.1 0.0 1.1 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal DUF1968 PF09291.5 KLO06294.1 - 0.047 13.4 0.0 0.08 12.7 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1968) Peptidase_C48 PF02902.14 KLO06295.1 - 1.2e-05 25.1 0.0 2.8e-05 23.8 0.0 1.6 1 1 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain GerPC PF10737.4 KLO06296.1 - 0.0065 16.2 4.5 0.1 12.3 0.1 2.3 2 0 0 2 2 2 2 Spore germination protein GerPC Baculo_PEP_C PF04513.7 KLO06296.1 - 0.12 12.2 0.5 0.46 10.2 0.0 2.2 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Streptin-Immun PF11083.3 KLO06296.1 - 0.16 11.9 2.9 5.9 6.9 0.1 3.1 3 0 0 3 3 3 0 Lantibiotic streptin immunity protein HTH_29 PF13551.1 KLO06298.1 - 1.6e-11 44.3 0.0 1.8e-11 44.2 0.0 1.0 1 0 0 1 1 1 1 Winged helix-turn helix HTH_32 PF13565.1 KLO06298.1 - 3.9e-08 33.9 0.0 5.2e-08 33.5 0.0 1.2 1 0 0 1 1 1 1 Homeodomain-like domain HTH_33 PF13592.1 KLO06298.1 - 1.1e-05 24.8 0.0 2e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 Winged helix-turn helix HTH_Tnp_Tc3_2 PF01498.13 KLO06298.1 - 0.00011 22.1 0.0 0.00029 20.8 0.0 1.7 2 0 0 2 2 2 1 Transposase HTH_23 PF13384.1 KLO06298.1 - 0.00024 20.6 0.3 0.013 15.1 0.0 2.2 2 0 0 2 2 2 1 Homeodomain-like domain HTH_28 PF13518.1 KLO06298.1 - 0.002 18.1 0.1 0.0081 16.1 0.0 1.8 2 0 0 2 2 2 1 Helix-turn-helix domain FUR PF01475.14 KLO06298.1 - 0.016 15.1 0.0 0.5 10.2 0.0 2.1 2 0 0 2 2 2 0 Ferric uptake regulator family Sigma70_r4_2 PF08281.7 KLO06298.1 - 0.016 14.6 0.1 1.7 8.2 0.0 2.3 2 1 0 2 2 2 0 Sigma-70, region 4 HTH_36 PF13730.1 KLO06298.1 - 0.059 13.5 0.2 0.21 11.7 0.1 1.8 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_11 PF08279.7 KLO06298.1 - 0.078 12.6 0.1 11 5.7 0.0 2.4 2 1 0 2 2 2 0 HTH domain TrmB PF01978.14 KLO06298.1 - 0.15 11.7 0.0 0.28 10.9 0.0 1.5 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB HTH_7 PF02796.10 KLO06298.1 - 0.17 11.7 0.8 3.5 7.5 0.0 2.8 3 1 0 3 3 3 0 Helix-turn-helix domain of resolvase Cut8_N PF14482.1 KLO06299.1 - 0.51 10.3 3.6 0.21 11.6 0.7 1.6 2 0 0 2 2 2 0 Cut8 proteasome-binding domain p450 PF00067.17 KLO06300.1 - 1.5e-70 237.9 0.0 1.9e-70 237.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Y_phosphatase PF00102.22 KLO06301.1 - 6.4e-30 104.2 0.0 1.1e-15 57.6 0.0 3.3 3 1 0 3 3 3 3 Protein-tyrosine phosphatase PTPlike_phytase PF14566.1 KLO06301.1 - 0.042 13.9 0.0 0.073 13.1 0.0 1.4 1 0 0 1 1 1 0 Inositol hexakisphosphate DLH PF01738.13 KLO06302.1 - 5.8e-26 91.1 0.2 6.7e-26 90.9 0.1 1.0 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 KLO06302.1 - 8.1e-08 32.1 0.0 1.1e-07 31.7 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 KLO06302.1 - 0.087 12.0 0.0 0.54 9.4 0.0 2.0 2 0 0 2 2 2 0 Prolyl oligopeptidase family Acetyltransf_3 PF13302.1 KLO06303.1 - 4.4e-06 26.9 0.0 5.7e-06 26.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 KLO06303.1 - 0.0081 16.1 0.1 0.023 14.7 0.0 1.8 2 1 0 2 2 2 1 Acetyltransferase (GNAT) family gag-asp_proteas PF13975.1 KLO06303.1 - 0.11 12.3 0.0 0.17 11.7 0.0 1.3 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease DUF2357 PF09823.4 KLO06303.1 - 0.14 11.2 0.0 0.19 10.7 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF2357) DLH PF01738.13 KLO06304.1 - 3.4e-07 29.7 0.0 4.7e-07 29.3 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 KLO06304.1 - 1.4e-06 28.1 0.0 2.1e-06 27.5 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family DLH PF01738.13 KLO06305.1 - 2.4e-09 36.7 0.0 3.3e-09 36.3 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 KLO06305.1 - 7e-07 29.1 0.0 1.1e-06 28.4 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family p450 PF00067.17 KLO06307.1 - 3.6e-72 243.3 0.0 4.4e-72 243.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Adaptin_N PF01602.15 KLO06308.1 - 2.3e-105 352.9 0.3 3.4e-105 352.3 0.2 1.2 1 0 0 1 1 1 1 Adaptin N terminal region HEAT_2 PF13646.1 KLO06308.1 - 1e-11 44.9 2.0 5.6e-05 23.3 0.0 5.0 4 3 3 7 7 7 4 HEAT repeats HEAT PF02985.17 KLO06308.1 - 6.9e-07 28.8 0.5 1.7 8.9 0.0 5.2 4 0 0 4 4 4 2 HEAT repeat Cnd1 PF12717.2 KLO06308.1 - 1e-06 28.6 0.2 0.034 14.0 0.3 2.7 2 0 0 2 2 2 2 non-SMC mitotic condensation complex subunit 1 RasGEF_N_2 PF14663.1 KLO06308.1 - 0.0002 21.2 1.9 0.14 12.1 0.0 3.5 4 0 0 4 4 4 2 Rapamycin-insensitive companion of mTOR RasGEF_N domain DUF2435 PF10363.4 KLO06308.1 - 0.00027 20.7 1.4 0.17 11.8 0.2 2.9 2 0 0 2 2 2 2 Protein of unknown function (DUF2435) HEAT_EZ PF13513.1 KLO06308.1 - 0.00037 20.8 4.2 4.8 7.8 0.0 5.6 5 1 1 6 6 6 1 HEAT-like repeat RIX1 PF08167.7 KLO06308.1 - 0.028 14.0 2.1 0.43 10.2 0.8 2.8 3 1 0 3 3 3 0 rRNA processing/ribosome biogenesis Arm PF00514.18 KLO06308.1 - 0.031 14.1 1.1 3.3 7.6 0.0 4.4 6 0 0 6 6 6 0 Armadillo/beta-catenin-like repeat Methyltransf_31 PF13847.1 KLO06309.1 - 2.7e-06 27.0 0.0 4.8e-06 26.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KLO06309.1 - 6.7e-06 26.5 0.0 1.4e-05 25.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KLO06309.1 - 7e-06 25.8 0.0 1.1e-05 25.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KLO06309.1 - 0.0061 17.1 0.0 0.028 14.9 0.0 2.1 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 KLO06309.1 - 0.015 15.6 0.0 0.049 14.0 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_12 PF08242.7 KLO06309.1 - 0.018 15.4 0.0 0.048 14.1 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase domain Ubie_methyltran PF01209.13 KLO06309.1 - 0.052 12.6 0.0 6.4 5.8 0.0 2.6 1 1 1 2 2 2 0 ubiE/COQ5 methyltransferase family Cytomega_gL PF01801.11 KLO06310.1 - 0.013 15.0 0.3 0.023 14.1 0.2 1.4 1 0 0 1 1 1 0 Cytomegalovirus glycoprotein L ArsA_ATPase PF02374.10 KLO06311.1 - 1.1e-109 366.1 0.3 1.3e-109 365.9 0.2 1.0 1 0 0 1 1 1 1 Anion-transporting ATPase CbiA PF01656.18 KLO06311.1 - 4.8e-15 55.4 0.0 1.1e-14 54.2 0.0 1.6 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.1 KLO06311.1 - 1.8e-10 40.9 0.0 4.3e-10 39.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain Fer4_NifH PF00142.13 KLO06311.1 - 3.5e-05 23.1 0.1 7.9e-05 21.9 0.0 1.6 2 0 0 2 2 2 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family SRP54 PF00448.17 KLO06311.1 - 6.1e-05 22.5 1.0 0.00097 18.6 0.1 2.4 2 1 1 3 3 3 1 SRP54-type protein, GTPase domain AAA_19 PF13245.1 KLO06311.1 - 0.0016 18.1 0.0 0.012 15.3 0.0 2.1 2 0 0 2 2 2 1 Part of AAA domain YhjQ PF06564.7 KLO06311.1 - 0.0038 16.6 0.0 0.0067 15.8 0.0 1.4 1 0 0 1 1 1 1 YhjQ protein VirC1 PF07015.6 KLO06311.1 - 0.008 15.2 0.1 0.019 14.0 0.0 1.5 1 1 0 1 1 1 1 VirC1 protein PhoH PF02562.11 KLO06311.1 - 0.0099 15.1 0.0 0.023 13.9 0.0 1.6 1 0 0 1 1 1 1 PhoH-like protein MipZ PF09140.6 KLO06311.1 - 0.012 14.7 0.1 0.022 13.8 0.0 1.5 1 1 0 1 1 1 0 ATPase MipZ AAA_25 PF13481.1 KLO06311.1 - 0.013 14.9 0.2 0.039 13.3 0.1 1.9 1 1 0 1 1 1 0 AAA domain IstB_IS21 PF01695.12 KLO06311.1 - 0.025 14.0 0.0 0.055 12.8 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein Elf1 PF05129.8 KLO06311.1 - 0.039 13.6 0.1 0.081 12.6 0.0 1.5 1 0 0 1 1 1 0 Transcription elongation factor Elf1 like AAA_10 PF12846.2 KLO06311.1 - 0.088 12.2 0.1 0.35 10.2 0.1 1.8 1 1 0 1 1 1 0 AAA-like domain Zeta_toxin PF06414.7 KLO06311.1 - 0.15 11.1 0.0 0.34 9.9 0.0 1.7 1 0 0 1 1 1 0 Zeta toxin PAP1 PF08601.5 KLO06312.1 - 2.4e-11 43.9 0.0 2.4e-11 43.9 0.0 4.2 1 1 3 4 4 4 1 Transcription factor PAP1 bZIP_1 PF00170.16 KLO06312.1 - 7.7e-10 38.5 12.2 7.7e-10 38.5 8.5 2.0 2 1 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.10 KLO06312.1 - 0.00049 19.8 13.6 0.00049 19.8 9.5 2.7 2 1 1 3 3 3 1 Basic region leucine zipper DUF724 PF05266.9 KLO06312.1 - 0.013 15.1 4.2 0.031 13.9 2.9 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF724) DUF972 PF06156.8 KLO06312.1 - 2.1 8.7 4.8 0.47 10.8 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF972) IncA PF04156.9 KLO06312.1 - 5.1 6.6 8.9 2.6 7.5 4.7 1.4 1 1 0 1 1 1 0 IncA protein PHD PF00628.24 KLO06313.1 - 3.2e-08 33.1 11.2 5.3e-08 32.4 7.7 1.3 1 0 0 1 1 1 1 PHD-finger PHD_3 PF13922.1 KLO06313.1 - 0.034 14.3 0.4 0.087 13.0 0.3 1.6 1 0 0 1 1 1 0 PHD domain of transcriptional enhancer, Asx PHD_2 PF13831.1 KLO06313.1 - 0.16 11.3 6.7 0.28 10.5 4.7 1.4 1 0 0 1 1 1 0 PHD-finger DNA_methylase PF00145.12 KLO06314.1 - 3.7e-28 98.6 0.0 4.9e-28 98.2 0.0 1.2 1 0 0 1 1 1 1 C-5 cytosine-specific DNA methylase eIF-5_eIF-2B PF01873.12 KLO06315.1 - 2.4e-39 133.8 0.0 4e-39 133.1 0.0 1.4 1 0 0 1 1 1 1 Domain found in IF2B/IF5 W2 PF02020.13 KLO06315.1 - 3.6e-28 97.3 0.5 3.6e-28 97.3 0.4 2.1 2 0 0 2 2 2 1 eIF4-gamma/eIF5/eIF2-epsilon Thiolase_C PF02803.13 KLO06316.1 - 3.9e-07 29.5 0.1 1.7e-06 27.4 0.0 2.0 2 0 0 2 2 2 1 Thiolase, C-terminal domain Thiolase_N PF00108.18 KLO06316.1 - 8.9e-07 28.1 0.0 5.8e-06 25.4 0.0 2.0 2 0 0 2 2 2 1 Thiolase, N-terminal domain ketoacyl-synt PF00109.21 KLO06316.1 - 0.00017 21.1 3.2 0.014 14.8 0.2 3.1 2 1 1 3 3 3 2 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.5 KLO06316.1 - 0.028 14.0 0.0 0.22 11.1 0.0 2.3 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III SMN PF06003.7 KLO06317.1 - 6.2 5.8 16.6 0.027 13.5 1.3 3.3 2 1 1 3 3 3 0 Survival motor neuron protein (SMN) Asp PF00026.18 KLO06318.1 - 1.2e-13 50.9 2.7 1.9e-13 50.3 1.9 1.2 1 0 0 1 1 1 1 Eukaryotic aspartyl protease Beta-APP PF03494.8 KLO06318.1 - 0.16 11.4 1.4 0.29 10.6 1.0 1.4 1 0 0 1 1 1 0 Beta-amyloid peptide (beta-APP) SKG6 PF08693.5 KLO06318.1 - 1.3 8.4 9.8 0.022 14.0 1.9 1.8 2 0 0 2 2 2 0 Transmembrane alpha-helix domain Reprolysin_5 PF13688.1 KLO06319.1 - 5.2e-43 147.2 8.2 5.2e-43 147.2 5.7 2.7 3 0 0 3 3 3 1 Metallo-peptidase family M12 Reprolysin_4 PF13583.1 KLO06319.1 - 1.4e-40 139.0 2.9 1.4e-40 139.0 2.0 2.1 2 1 0 3 3 3 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.1 KLO06319.1 - 1.7e-37 129.1 4.9 1.7e-37 129.1 3.4 2.5 2 1 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_3 PF13582.1 KLO06319.1 - 7e-20 71.7 0.2 7e-20 71.7 0.1 3.1 2 1 1 3 3 3 1 Metallo-peptidase family M12B Reprolysin-like Disintegrin PF00200.18 KLO06319.1 - 4e-16 59.0 23.8 4e-16 59.0 16.5 4.7 2 2 2 4 4 4 1 Disintegrin Reprolysin PF01421.14 KLO06319.1 - 4.4e-05 23.1 9.2 4.4e-05 23.1 6.4 3.3 2 1 0 2 2 2 1 Reprolysin (M12B) family zinc metalloprotease Pep_M12B_propep PF01562.14 KLO06319.1 - 0.0011 18.7 0.0 0.0022 17.7 0.0 1.4 1 0 0 1 1 1 1 Reprolysin family propeptide Peptidase_M43 PF05572.8 KLO06319.1 - 0.012 15.1 0.1 0.036 13.6 0.1 1.8 1 0 0 1 1 1 0 Pregnancy-associated plasma protein-A Peptidase_M54 PF07998.6 KLO06319.1 - 0.33 10.7 0.6 0.72 9.5 0.4 1.5 1 0 0 1 1 1 0 Peptidase family M54 Brr6_like_C_C PF10104.4 KLO06320.1 - 5.4e-42 142.4 0.8 7e-42 142.1 0.5 1.1 1 0 0 1 1 1 1 Di-sulfide bridge nucleocytoplasmic transport domain SUR7 PF06687.7 KLO06320.1 - 0.012 15.2 0.0 0.017 14.7 0.0 1.2 1 0 0 1 1 1 0 SUR7/PalI family CLP_protease PF00574.18 KLO06321.1 - 1.1e-73 246.7 0.0 1.5e-73 246.3 0.0 1.1 1 0 0 1 1 1 1 Clp protease Ribosomal_S21 PF01165.15 KLO06321.1 - 0.03 13.7 0.1 0.057 12.8 0.1 1.4 1 0 0 1 1 1 0 Ribosomal protein S21 F-box-like PF12937.2 KLO06324.1 - 1.1e-08 34.6 0.0 2.7e-08 33.3 0.0 1.7 1 0 0 1 1 1 1 F-box-like F-box-like_2 PF13013.1 KLO06324.1 - 0.0013 18.4 0.0 0.0045 16.6 0.0 1.9 1 0 0 1 1 1 1 F-box-like domain F-box PF00646.28 KLO06324.1 - 0.078 12.6 1.5 5.9 6.6 0.0 2.6 2 0 0 2 2 2 0 F-box domain SNARE_assoc PF09335.6 KLO06327.1 - 1.8e-12 47.5 10.8 4.2e-12 46.3 7.5 1.6 1 0 0 1 1 1 1 SNARE associated Golgi protein F-box-like PF12937.2 KLO06332.1 - 2.8e-06 26.9 0.0 7.7e-06 25.5 0.0 1.8 1 0 0 1 1 1 1 F-box-like F-box-like PF12937.2 KLO06333.1 - 1.6e-06 27.6 0.0 4.8e-06 26.1 0.0 1.9 1 0 0 1 1 1 1 F-box-like F-box-like PF12937.2 KLO06334.1 - 8.3e-08 31.8 0.0 8.3e-08 31.8 0.0 2.7 3 0 0 3 3 3 1 F-box-like F-box PF00646.28 KLO06334.1 - 0.063 12.9 0.0 0.44 10.2 0.0 2.5 2 1 0 2 2 2 0 F-box domain PA28_beta PF02252.13 KLO06334.1 - 0.12 11.8 0.0 0.3 10.5 0.0 1.6 2 0 0 2 2 2 0 Proteasome activator pa28 beta subunit F-box-like PF12937.2 KLO06335.1 - 1.1e-08 34.6 0.0 2.8e-08 33.3 0.0 1.8 1 0 0 1 1 1 1 F-box-like F-box-like PF12937.2 KLO06336.1 - 1.4e-07 31.1 0.5 3.6e-07 29.8 0.0 2.0 2 0 0 2 2 2 1 F-box-like F-box-like PF12937.2 KLO06337.1 - 1.9e-06 27.4 0.0 1.9e-06 27.4 0.0 2.7 3 0 0 3 3 3 1 F-box-like F-box PF00646.28 KLO06337.1 - 0.008 15.8 2.9 0.032 13.9 0.0 3.3 3 0 0 3 3 3 1 F-box domain F-box-like PF12937.2 KLO06338.1 - 8.6e-07 28.5 0.1 4e-06 26.4 0.0 2.2 2 0 0 2 2 2 1 F-box-like F-box-like PF12937.2 KLO06339.1 - 1.7e-05 24.4 0.2 1.7e-05 24.4 0.1 2.7 3 0 0 3 3 3 1 F-box-like F-box PF00646.28 KLO06339.1 - 0.011 15.3 0.1 0.044 13.4 0.0 2.1 1 0 0 1 1 1 0 F-box domain DUF2181 PF10223.4 KLO06339.1 - 0.03 13.6 0.0 0.05 12.9 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2181) F-box-like PF12937.2 KLO06340.1 - 9.2e-05 22.0 0.1 0.00022 20.8 0.1 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KLO06340.1 - 0.0012 18.4 0.1 0.0037 16.8 0.1 1.8 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 KLO06341.1 - 9.4e-08 31.6 0.7 9.4e-08 31.6 0.5 2.0 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 KLO06341.1 - 0.00063 19.3 0.1 0.0027 17.2 0.1 2.1 1 0 0 1 1 1 1 F-box domain LRR_1 PF00560.28 KLO06341.1 - 0.76 10.0 2.9 8.9 6.7 0.1 3.9 3 0 0 3 3 3 0 Leucine Rich Repeat LRR_7 PF13504.1 KLO06341.1 - 1.4 9.4 3.6 1.1e+02 3.7 0.0 4.3 5 0 0 5 5 5 0 Leucine rich repeat APH PF01636.18 KLO06342.1 - 2e-11 44.0 0.0 3.4e-11 43.3 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family F-box-like PF12937.2 KLO06343.1 - 2.3e-08 33.6 0.4 2.3e-08 33.6 0.3 2.2 3 0 0 3 3 3 1 F-box-like F-box PF00646.28 KLO06343.1 - 0.048 13.3 3.1 0.32 10.6 1.5 2.9 2 1 0 2 2 2 0 F-box domain APH PF01636.18 KLO06344.1 - 3e-09 36.9 0.0 4.1e-09 36.5 0.0 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family DUF605 PF04652.11 KLO06347.1 - 2.3 7.5 16.4 2.8 7.2 11.4 1.1 1 0 0 1 1 1 0 Vta1 like Con-6 PF10346.4 KLO06350.1 - 2e-10 39.8 0.3 3.1e-10 39.2 0.2 1.3 1 0 0 1 1 1 1 Conidiation protein 6 A_deamin PF02137.13 KLO06351.1 - 1e-69 235.4 0.0 1.3e-69 235.1 0.0 1.1 1 0 0 1 1 1 1 Adenosine-deaminase (editase) domain DUF2838 PF10998.3 KLO06352.1 - 2.1e-39 133.8 9.1 4.6e-39 132.7 6.3 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2838) Mt_ATP-synt_D PF05873.7 KLO06353.1 - 4.1e-11 42.7 1.6 4.8e-11 42.5 1.1 1.1 1 0 0 1 1 1 1 ATP synthase D chain, mitochondrial (ATP5H) Aminotran_3 PF00202.16 KLO06353.1 - 0.023 13.5 1.6 0.73 8.6 0.2 2.3 1 1 1 2 2 2 0 Aminotransferase class-III LsmAD PF06741.8 KLO06353.1 - 0.052 13.6 2.2 0.068 13.2 0.1 2.0 2 0 0 2 2 2 0 LsmAD domain DUF2536 PF10750.4 KLO06353.1 - 0.19 11.3 1.3 0.24 11.0 0.2 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2536) Cauli_AT PF03233.8 KLO06353.1 - 1.4 8.6 4.5 0.54 9.9 1.2 1.9 2 1 0 2 2 2 0 Aphid transmission protein F-box-like PF12937.2 KLO06354.1 - 0.00032 20.3 1.4 0.00032 20.3 1.0 2.1 3 0 0 3 3 3 1 F-box-like Drf_FH1 PF06346.7 KLO06354.1 - 0.12 11.8 3.4 6.1 6.3 0.1 2.2 2 0 0 2 2 2 0 Formin Homology Region 1 Hexokinase_2 PF03727.11 KLO06355.1 - 2.8e-67 226.4 0.0 3.8e-67 226.0 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.16 KLO06355.1 - 8.6e-67 224.4 0.0 1.3e-66 223.8 0.0 1.2 1 0 0 1 1 1 1 Hexokinase DUF972 PF06156.8 KLO06357.1 - 0.059 13.7 0.5 0.21 11.9 0.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF972) F-box-like PF12937.2 KLO06362.1 - 2.4e-06 27.1 0.2 1.2e-05 24.9 0.0 2.3 2 0 0 2 2 2 1 F-box-like F-box-like PF12937.2 KLO06363.1 - 0.11 12.2 0.0 0.27 11.0 0.0 1.7 1 0 0 1 1 1 0 F-box-like F-box-like PF12937.2 KLO06364.1 - 0.079 12.7 0.0 0.3 10.8 0.0 2.0 1 0 0 1 1 1 0 F-box-like DUF3129 PF11327.3 KLO06366.1 - 6.2e-53 179.3 13.5 6.2e-53 179.3 9.4 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF3129) I-set PF07679.11 KLO06366.1 - 0.0033 17.2 0.1 0.0061 16.3 0.0 1.5 1 0 0 1 1 1 1 Immunoglobulin I-set domain Ig_2 PF13895.1 KLO06366.1 - 0.037 14.1 0.1 0.069 13.2 0.1 1.5 1 0 0 1 1 1 0 Immunoglobulin domain DUF3129 PF11327.3 KLO06367.1 - 7.1e-55 185.6 6.8 8.3e-55 185.4 4.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3129) Oxidored_FMN PF00724.15 KLO06368.1 - 2.7e-69 233.7 0.0 3.4e-69 233.4 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family F-box-like PF12937.2 KLO06369.1 - 3.3e-07 29.9 0.0 9.1e-07 28.5 0.0 1.9 1 0 0 1 1 1 1 F-box-like F-box-like PF12937.2 KLO06370.1 - 2.9e-09 36.5 0.2 1.1e-07 31.5 0.0 2.6 2 0 0 2 2 2 1 F-box-like F-box-like PF12937.2 KLO06371.1 - 4.8e-05 22.9 0.1 0.00016 21.2 0.0 2.0 2 0 0 2 2 2 1 F-box-like F-box-like PF12937.2 KLO06372.1 - 5.7e-06 25.9 1.1 9.2e-06 25.2 0.0 2.0 2 0 0 2 2 2 1 F-box-like DUF1180 PF06679.7 KLO06373.1 - 0.22 11.3 0.9 0.25 11.2 0.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) Pkinase PF00069.20 KLO06374.1 - 1.7e-33 115.8 0.0 2.1e-33 115.5 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KLO06374.1 - 1.8e-32 112.4 0.0 2.2e-32 112.1 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KLO06374.1 - 0.03 13.2 0.0 0.037 12.9 0.0 1.1 1 0 0 1 1 1 0 Kinase-like APH PF01636.18 KLO06374.1 - 0.067 12.9 0.0 0.086 12.5 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pkinase PF00069.20 KLO06375.1 - 8.3e-40 136.5 0.0 1e-39 136.2 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KLO06375.1 - 1.1e-38 132.7 0.0 1.4e-38 132.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KLO06375.1 - 0.00038 19.5 0.0 0.00055 18.9 0.0 1.1 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 KLO06375.1 - 0.0064 16.2 0.0 0.0099 15.6 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.17 KLO06375.1 - 0.041 13.2 0.0 0.061 12.6 0.0 1.2 1 0 0 1 1 1 0 RIO1 family CAS_CSE1 PF03378.10 KLO06376.1 - 0.0071 14.6 0.0 0.016 13.5 0.0 1.6 2 0 0 2 2 2 1 CAS/CSE protein, C-terminus Helicase_C PF00271.26 KLO06377.1 - 2.6e-17 62.4 0.2 4.9e-16 58.3 0.1 2.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.24 KLO06377.1 - 7.2e-09 35.3 0.0 8.9e-08 31.8 0.0 2.4 1 1 0 1 1 1 1 DEAD/DEAH box helicase GBP_C PF02841.9 KLO06377.1 - 0.015 14.5 11.1 0.03 13.5 7.7 1.4 1 0 0 1 1 1 0 Guanylate-binding protein, C-terminal domain Phage_GPO PF05929.6 KLO06377.1 - 0.061 12.5 9.3 0.13 11.4 6.5 1.5 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase U79_P34 PF03064.11 KLO06377.1 - 8.9 5.7 13.7 20 4.5 9.5 1.5 1 0 0 1 1 1 0 HSV U79 / HCMV P34 Pkinase_Tyr PF07714.12 KLO06381.1 - 1.8e-33 115.7 0.0 2.5e-30 105.4 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 KLO06381.1 - 2.6e-33 115.2 0.0 1.1e-31 109.9 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain EST1_DNA_bind PF10373.4 KLO06384.1 - 0.012 14.8 0.6 0.021 14.0 0.4 1.4 1 0 0 1 1 1 0 Est1 DNA/RNA binding domain DUF2730 PF10805.3 KLO06384.1 - 0.045 13.4 10.1 0.95 9.2 0.3 3.8 4 0 0 4 4 4 0 Protein of unknown function (DUF2730) Peptidase_S46 PF10459.4 KLO06384.1 - 0.11 10.8 7.4 0.15 10.4 5.1 1.1 1 0 0 1 1 1 0 Peptidase S46 TPR_MLP1_2 PF07926.7 KLO06384.1 - 0.14 11.9 22.4 0.23 11.2 6.7 3.2 3 0 0 3 3 3 0 TPR/MLP1/MLP2-like protein DUF745 PF05335.8 KLO06384.1 - 0.32 10.4 8.7 3 7.3 2.6 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF745) CCDC-167 PF15188.1 KLO06384.1 - 0.51 10.3 11.9 0.3 11.0 3.2 3.2 3 0 0 3 3 3 0 Coiled-coil domain-containing protein 167 DUF479 PF04336.7 KLO06384.1 - 0.54 10.3 3.9 3.8 7.6 0.1 3.3 3 2 0 3 3 3 0 Protein of unknown function, DUF479 Med9 PF07544.8 KLO06384.1 - 0.81 9.4 8.2 0.24 11.1 0.1 3.5 4 0 0 4 4 4 0 RNA polymerase II transcription mediator complex subunit 9 AKNA PF12443.3 KLO06384.1 - 0.83 9.7 6.0 3.2 7.8 0.0 3.2 2 2 2 4 4 4 0 AT-hook-containing transcription factor HSA PF07529.8 KLO06384.1 - 1.1 9.0 8.4 0.76 9.6 0.1 3.1 2 1 0 2 2 2 0 HSA NPV_P10 PF05531.7 KLO06384.1 - 1.3 9.3 8.1 3.2 8.0 0.2 3.6 3 1 1 4 4 4 0 Nucleopolyhedrovirus P10 protein AMP-binding_C_2 PF14535.1 KLO06384.1 - 1.5 8.9 5.2 0.41 10.7 0.4 2.4 2 1 1 3 3 3 0 AMP-binding enzyme C-terminal domain DUF1664 PF07889.7 KLO06384.1 - 1.8 8.3 14.1 6.4 6.5 0.1 3.4 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) FliJ PF02050.11 KLO06384.1 - 9.6 6.2 19.3 1 9.4 0.5 3.7 3 1 0 3 3 3 0 Flagellar FliJ protein CENP-F_leu_zip PF10473.4 KLO06386.1 - 0.0012 18.7 0.5 0.003 17.3 0.4 1.6 1 0 0 1 1 1 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Reo_sigmaC PF04582.7 KLO06386.1 - 0.0094 15.1 0.9 0.033 13.3 0.3 2.1 2 0 0 2 2 2 1 Reovirus sigma C capsid protein DUF4477 PF14780.1 KLO06386.1 - 0.032 13.5 0.1 0.067 12.5 0.1 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4477) DUF812 PF05667.6 KLO06386.1 - 0.036 12.6 1.6 0.079 11.4 1.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF812) DUF2659 PF10858.3 KLO06386.1 - 0.054 12.8 0.1 0.076 12.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2659) DUF2130 PF09903.4 KLO06386.1 - 0.057 12.1 0.2 2.7 6.6 0.0 2.4 2 1 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2130) Borrelia_lipo_1 PF05714.6 KLO06386.1 - 0.058 12.4 0.9 0.1 11.7 0.7 1.4 1 0 0 1 1 1 0 Borrelia burgdorferi virulent strain associated lipoprotein IncA PF04156.9 KLO06386.1 - 0.059 12.9 0.7 0.12 11.9 0.5 1.5 1 0 0 1 1 1 0 IncA protein APG17 PF04108.7 KLO06386.1 - 0.06 12.1 1.3 0.35 9.6 0.7 2.0 1 1 1 2 2 2 0 Autophagy protein Apg17 TUDOR PF00567.19 KLO06386.1 - 0.13 12.1 0.0 0.38 10.6 0.0 1.7 1 1 0 1 1 1 0 Tudor domain Zn_clus PF00172.13 KLO06387.1 - 0.0016 18.3 10.5 0.0028 17.5 7.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain P30 PF07390.6 KLO06389.1 - 0.038 13.5 0.1 0.058 12.9 0.1 1.2 1 0 0 1 1 1 0 Mycoplasma P30 protein DUF4650 PF15509.1 KLO06389.1 - 0.18 10.6 1.9 0.24 10.2 1.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4650) Zn_clus PF00172.13 KLO06389.1 - 0.22 11.4 14.9 0.39 10.6 10.3 1.5 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain BRAP2 PF07576.7 KLO06390.1 - 0.047 13.2 0.0 0.068 12.7 0.0 1.3 1 0 0 1 1 1 0 BRCA1-associated protein 2 Gemini_coat PF00844.13 KLO06393.1 - 0.12 11.5 0.0 0.14 11.3 0.0 1.1 1 0 0 1 1 1 0 Geminivirus coat protein/nuclear export factor BR1 family CobT PF06213.7 KLO06396.1 - 0.48 9.4 13.8 1.2 8.2 9.5 1.6 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT TFIIA PF03153.8 KLO06396.1 - 0.57 10.0 19.9 0.028 14.3 9.6 1.8 2 1 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Nucleo_P87 PF07267.6 KLO06396.1 - 4.2 5.9 9.7 6.3 5.3 6.7 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 PPTA PF01239.17 KLO06398.1 - 4.8e-40 133.2 8.8 4.4e-08 32.1 0.0 5.5 5 0 0 5 5 5 5 Protein prenyltransferase alpha subunit repeat RNA_pol_3_Rpc31 PF11705.3 KLO06399.1 - 5.3e-32 111.6 30.9 3.5e-31 108.9 21.4 1.9 1 1 0 1 1 1 1 DNA-directed RNA polymerase III subunit Rpc31 Sugar_tr PF00083.19 KLO06400.1 - 7e-82 275.3 20.8 8.2e-82 275.1 14.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KLO06400.1 - 1.9e-27 95.9 37.8 2e-22 79.3 12.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 KLO06400.1 - 0.00037 19.0 25.3 0.00072 18.0 1.6 2.8 2 1 0 2 2 2 2 MFS/sugar transport protein Gate PF07670.9 KLO06400.1 - 0.16 11.8 5.2 0.7 9.8 3.6 2.2 1 1 0 1 1 1 0 Nucleoside recognition MAM33 PF02330.11 KLO06401.1 - 2.1e-37 128.8 0.0 2.5e-37 128.6 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial glycoprotein DUF2112 PF09885.4 KLO06401.1 - 0.085 12.5 0.0 0.15 11.7 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2112) Homoserine_dh PF00742.14 KLO06402.1 - 8.8e-45 152.5 0.0 1.3e-44 151.9 0.0 1.3 1 0 0 1 1 1 1 Homoserine dehydrogenase NAD_binding_3 PF03447.11 KLO06402.1 - 4.1e-14 52.9 0.0 1.1e-13 51.5 0.0 1.8 1 1 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain Semialdhyde_dh PF01118.19 KLO06402.1 - 0.003 17.8 0.0 0.035 14.4 0.0 2.6 1 1 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain FA_desaturase PF00487.19 KLO06403.1 - 1.6e-23 83.5 27.6 2.4e-23 82.9 19.1 1.3 1 0 0 1 1 1 1 Fatty acid desaturase DUF3474 PF11960.3 KLO06403.1 - 0.00039 20.4 0.0 0.00066 19.7 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3474) Abhydrolase_6 PF12697.2 KLO06404.1 - 3.6e-15 56.4 0.8 4.5e-15 56.1 0.6 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KLO06404.1 - 0.0019 17.9 0.0 0.0066 16.1 0.0 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Cytochrom_B561 PF03188.11 KLO06405.1 - 1.2e-13 51.0 5.8 1.2e-13 51.0 4.0 1.9 1 1 1 2 2 2 1 Eukaryotic cytochrome b561 DUF4271 PF14093.1 KLO06405.1 - 0.0018 18.0 0.6 0.0025 17.5 0.1 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF4271) DUF4149 PF13664.1 KLO06405.1 - 0.036 14.1 5.6 0.038 14.0 1.1 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4149) Cytochrom_B_N PF00033.14 KLO06405.1 - 0.043 13.1 12.4 0.3 10.4 8.6 2.3 1 1 0 1 1 1 0 Cytochrome b(N-terminal)/b6/petB DUF4079 PF13301.1 KLO06405.1 - 0.18 11.7 7.2 1.2 9.1 2.6 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF4079) Ni_hydr_CYTB PF01292.15 KLO06405.1 - 0.78 9.0 13.9 4.9 6.5 9.6 2.3 1 1 0 1 1 1 0 Prokaryotic cytochrome b561 DUF2231 PF09990.4 KLO06405.1 - 3.5 8.0 11.5 0.21 11.9 3.8 2.0 2 1 0 2 2 2 0 Predicted membrane protein (DUF2231) DUF2306 PF10067.4 KLO06405.1 - 3.6 7.7 15.3 0.17 11.9 0.9 3.2 2 1 1 3 3 3 0 Predicted membrane protein (DUF2306) Aldo_ket_red PF00248.16 KLO06407.1 - 2.7e-41 141.2 0.0 3.6e-41 140.8 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family 2-oxoacid_dh PF00198.18 KLO06408.1 - 1.2e-80 270.1 0.0 1.5e-80 269.7 0.0 1.1 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.17 KLO06408.1 - 2.6e-20 71.8 1.2 4.9e-20 70.9 0.8 1.5 1 0 0 1 1 1 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.1 KLO06408.1 - 0.0012 18.5 0.3 0.098 12.3 0.0 2.4 1 1 1 2 2 2 1 Biotin-lipoyl like HlyD_3 PF13437.1 KLO06408.1 - 0.0048 17.2 0.2 1.8 8.9 0.0 2.3 1 1 1 2 2 2 2 HlyD family secretion protein GCV_H PF01597.14 KLO06408.1 - 0.012 15.2 0.2 0.025 14.2 0.1 1.5 1 0 0 1 1 1 0 Glycine cleavage H-protein DUF605 PF04652.11 KLO06408.1 - 0.073 12.4 14.1 0.092 12.1 9.8 1.1 1 0 0 1 1 1 0 Vta1 like GMP_PDE_delta PF05351.6 KLO06408.1 - 0.14 11.9 0.0 0.27 11.0 0.0 1.4 1 0 0 1 1 1 0 GMP-PDE, delta subunit DUF4551 PF15087.1 KLO06408.1 - 0.69 8.2 6.0 1 7.6 4.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) YL1 PF05764.8 KLO06408.1 - 0.74 9.3 8.7 1 8.8 6.0 1.2 1 0 0 1 1 1 0 YL1 nuclear protein Pneumo_att_G PF05539.6 KLO06408.1 - 1.3 8.2 8.8 2 7.7 6.1 1.2 1 0 0 1 1 1 0 Pneumovirinae attachment membrane glycoprotein G SpoIIIAH PF12685.2 KLO06408.1 - 4 6.8 9.6 8.5 5.8 0.2 2.4 3 0 0 3 3 3 0 SpoIIIAH-like protein Neisseria_TspB PF05616.8 KLO06408.1 - 6.2 5.0 13.5 8.8 4.5 9.3 1.1 1 0 0 1 1 1 0 Neisseria meningitidis TspB protein 7TM-7TMR_HD PF07698.6 KLO06410.1 - 0.028 13.8 0.6 0.044 13.2 0.4 1.3 1 0 0 1 1 1 0 7TM receptor with intracellular HD hydrolase WD40 PF00400.27 KLO06411.1 - 4.5e-67 219.7 32.3 2.2e-12 46.3 0.1 7.9 7 0 0 7 7 7 7 WD domain, G-beta repeat AAA_22 PF13401.1 KLO06411.1 - 5e-12 46.1 0.0 4.1e-05 23.7 0.0 3.1 2 1 0 2 2 2 2 AAA domain NACHT PF05729.7 KLO06411.1 - 1.1e-10 41.4 0.1 9.8e-06 25.3 0.0 3.3 2 1 0 2 2 2 2 NACHT domain AAA_16 PF13191.1 KLO06411.1 - 2.5e-10 40.6 0.2 0.00024 21.1 0.0 3.2 3 0 0 3 3 2 2 AAA ATPase domain AAA PF00004.24 KLO06411.1 - 2.5e-08 34.1 0.0 0.011 15.9 0.0 3.0 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 KLO06411.1 - 3.7e-08 34.2 0.0 0.021 15.6 0.0 3.5 3 0 0 3 3 2 2 AAA domain NB-ARC PF00931.17 KLO06411.1 - 6.3e-08 31.8 0.0 7.6e-05 21.7 0.0 3.5 3 1 0 3 3 3 1 NB-ARC domain AAA_18 PF13238.1 KLO06411.1 - 7.3e-07 29.5 0.0 0.061 13.6 0.0 2.9 2 1 0 2 2 2 2 AAA domain RNA_helicase PF00910.17 KLO06411.1 - 1.2e-06 28.6 0.0 0.11 12.6 0.0 3.2 3 0 0 3 3 2 2 RNA helicase APS_kinase PF01583.15 KLO06411.1 - 1.3e-06 28.1 0.0 0.023 14.3 0.0 2.6 2 0 0 2 2 2 2 Adenylylsulphate kinase Zeta_toxin PF06414.7 KLO06411.1 - 2.7e-06 26.6 0.0 0.064 12.3 0.0 2.5 2 0 0 2 2 2 2 Zeta toxin AAA_25 PF13481.1 KLO06411.1 - 3.2e-06 26.6 0.0 0.028 13.8 0.0 2.9 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.1 KLO06411.1 - 1.9e-05 24.3 0.0 0.021 14.5 0.0 2.7 2 0 0 2 2 2 1 Part of AAA domain AAA_33 PF13671.1 KLO06411.1 - 2.2e-05 24.3 0.0 0.12 12.2 0.0 2.8 2 0 0 2 2 2 2 AAA domain DUF2075 PF09848.4 KLO06411.1 - 3.3e-05 23.0 0.0 0.17 10.7 0.0 2.2 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2075) Nbas_N PF15492.1 KLO06411.1 - 5.8e-05 22.3 0.3 0.04 13.0 0.0 3.9 3 1 0 3 3 3 1 Neuroblastoma-amplified sequence, N terminal eIF2A PF08662.6 KLO06411.1 - 0.00014 21.6 0.0 0.049 13.3 0.0 2.6 3 0 0 3 3 2 1 Eukaryotic translation initiation factor eIF2A MobB PF03205.9 KLO06411.1 - 0.00023 20.9 0.1 0.0018 17.9 0.0 2.5 3 0 0 3 3 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_28 PF13521.1 KLO06411.1 - 0.00039 20.4 0.0 0.32 10.9 0.0 2.5 2 0 0 2 2 2 1 AAA domain Nucleoporin_N PF08801.6 KLO06411.1 - 0.00045 19.0 0.8 0.009 14.7 0.1 2.2 1 1 1 2 2 2 1 Nup133 N terminal like AAA_14 PF13173.1 KLO06411.1 - 0.0012 18.7 0.0 4.1 7.3 0.0 4.0 3 1 0 3 3 2 0 AAA domain KAP_NTPase PF07693.9 KLO06411.1 - 0.0014 17.7 0.5 0.35 9.7 0.1 3.1 3 0 0 3 3 3 1 KAP family P-loop domain RuvB_N PF05496.7 KLO06411.1 - 0.0016 17.5 0.0 0.22 10.5 0.0 2.2 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus Viral_helicase1 PF01443.13 KLO06411.1 - 0.0035 16.8 0.0 2.2 7.7 0.0 2.4 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase IstB_IS21 PF01695.12 KLO06411.1 - 0.0039 16.6 0.0 2.4 7.5 0.0 2.5 2 0 0 2 2 2 1 IstB-like ATP binding protein ABC_tran PF00005.22 KLO06411.1 - 0.0049 17.1 0.0 1.8 8.8 0.0 2.7 2 0 0 2 2 2 1 ABC transporter NTPase_1 PF03266.10 KLO06411.1 - 0.007 16.0 0.0 0.13 11.9 0.0 2.5 2 0 0 2 2 2 1 NTPase TIP49 PF06068.8 KLO06411.1 - 0.0076 15.0 0.0 3.2 6.3 0.0 2.2 2 0 0 2 2 2 0 TIP49 C-terminus KTI12 PF08433.5 KLO06411.1 - 0.0097 15.1 0.0 0.7 9.0 0.0 2.6 3 0 0 3 3 2 1 Chromatin associated protein KTI12 ArgK PF03308.11 KLO06411.1 - 0.017 13.9 0.0 1.5 7.5 0.0 2.2 2 0 0 2 2 2 0 ArgK protein Rad17 PF03215.10 KLO06411.1 - 0.025 13.2 0.0 2.6 6.6 0.0 2.2 2 0 0 2 2 2 0 Rad17 cell cycle checkpoint protein AAA_10 PF12846.2 KLO06411.1 - 0.033 13.6 0.0 1.4 8.2 0.0 2.7 2 0 0 2 2 2 0 AAA-like domain Torsin PF06309.6 KLO06411.1 - 0.037 13.9 0.0 13 5.6 0.0 2.8 2 0 0 2 2 2 0 Torsin AAA_30 PF13604.1 KLO06411.1 - 0.038 13.5 0.1 0.88 9.1 0.0 2.3 2 0 0 2 2 2 0 AAA domain PD40 PF07676.7 KLO06411.1 - 0.044 13.4 0.3 74 3.1 0.0 4.7 5 0 0 5 5 4 0 WD40-like Beta Propeller Repeat FtsK_SpoIIIE PF01580.13 KLO06411.1 - 0.044 13.2 0.0 6.4 6.1 0.0 2.7 3 0 0 3 3 2 0 FtsK/SpoIIIE family CbiA PF01656.18 KLO06411.1 - 0.061 12.7 0.0 1.7 8.0 0.0 2.6 2 0 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain Arch_ATPase PF01637.13 KLO06411.1 - 0.064 12.9 0.0 3.7 7.1 0.0 3.1 3 0 0 3 3 3 0 Archaeal ATPase Parvo_NS1 PF01057.12 KLO06411.1 - 0.07 11.9 0.0 3.3 6.4 0.0 2.3 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 AAA_5 PF07728.9 KLO06411.1 - 0.077 12.7 0.0 8.3 6.1 0.0 2.8 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) TrwB_AAD_bind PF10412.4 KLO06411.1 - 0.08 11.5 0.0 3 6.3 0.0 2.5 3 0 0 3 3 2 0 Type IV secretion-system coupling protein DNA-binding domain ADK PF00406.17 KLO06411.1 - 0.081 12.7 0.1 2.5 7.9 0.0 2.6 2 0 0 2 2 2 0 Adenylate kinase SRP54 PF00448.17 KLO06411.1 - 0.11 11.9 0.0 0.6 9.5 0.0 2.2 3 0 0 3 3 2 0 SRP54-type protein, GTPase domain Mg_chelatase PF01078.16 KLO06411.1 - 0.14 11.2 0.0 19 4.3 0.0 2.3 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_11 PF13086.1 KLO06411.1 - 0.17 11.4 0.0 8.8 5.8 0.0 2.6 2 0 0 2 2 2 0 AAA domain PhoH PF02562.11 KLO06411.1 - 0.17 11.0 0.0 7.8 5.6 0.0 2.4 2 0 0 2 2 2 0 PhoH-like protein ResIII PF04851.10 KLO06411.1 - 0.21 11.4 0.0 4.3 7.1 0.0 2.4 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit zf-C2H2 PF00096.21 KLO06412.1 - 2.5e-09 36.9 10.3 0.0032 17.7 0.3 3.3 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KLO06412.1 - 1.1e-07 31.7 10.2 0.023 14.9 0.4 3.2 3 0 0 3 3 3 3 C2H2-type zinc finger zf-H2C2_5 PF13909.1 KLO06412.1 - 3.1e-05 23.9 8.0 0.0031 17.6 0.5 3.5 3 0 0 3 3 3 1 C2H2-type zinc-finger domain zf-H2C2_2 PF13465.1 KLO06412.1 - 0.0026 17.9 18.3 0.0041 17.3 0.4 4.2 4 1 0 4 4 4 2 Zinc-finger double domain IBR PF01485.16 KLO06412.1 - 0.008 16.0 5.0 0.091 12.6 0.5 2.2 2 0 0 2 2 2 1 IBR domain zf-met PF12874.2 KLO06412.1 - 0.012 15.8 1.9 6.1 7.1 0.1 3.2 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zinc_ribbon_5 PF13719.1 KLO06412.1 - 0.064 12.8 0.7 0.16 11.5 0.5 1.7 1 0 0 1 1 1 0 zinc-ribbon domain zf-BED PF02892.10 KLO06412.1 - 0.071 12.8 3.6 1.4 8.7 0.6 2.7 2 1 0 2 2 2 0 BED zinc finger zinc_ribbon_4 PF13717.1 KLO06412.1 - 0.092 12.4 0.9 0.25 11.0 0.6 1.8 1 0 0 1 1 1 0 zinc-ribbon domain zf-C2H2_7 PF15269.1 KLO06412.1 - 0.21 11.5 2.7 0.65 9.9 0.4 2.3 1 1 1 2 2 2 0 Zinc-finger zf-C2H2_6 PF13912.1 KLO06412.1 - 0.7 9.8 5.8 5 7.1 0.9 2.7 3 0 0 3 3 3 0 C2H2-type zinc finger DUF3617 PF12276.3 KLO06414.1 - 0.03 13.7 0.1 0.044 13.2 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3617) WD40 PF00400.27 KLO06419.1 - 5.4e-60 197.2 31.6 4.7e-13 48.4 0.4 7.7 7 0 0 7 7 7 7 WD domain, G-beta repeat AAA_16 PF13191.1 KLO06419.1 - 2e-13 50.7 0.0 4.8e-05 23.4 0.0 3.2 2 1 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.1 KLO06419.1 - 9.9e-13 48.3 0.0 2.3e-05 24.5 0.0 2.8 2 0 0 2 2 2 2 AAA domain NACHT PF05729.7 KLO06419.1 - 2.9e-12 46.5 0.0 7e-06 25.8 0.0 2.9 2 1 0 2 2 2 2 NACHT domain NB-ARC PF00931.17 KLO06419.1 - 8.4e-11 41.2 0.0 5.5e-06 25.4 0.0 2.8 2 1 0 2 2 2 2 NB-ARC domain AAA PF00004.24 KLO06419.1 - 5.5e-09 36.3 0.0 0.0039 17.4 0.0 2.9 2 2 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 KLO06419.1 - 2.5e-08 34.7 0.6 0.0068 17.2 0.0 3.4 3 1 0 3 3 2 2 AAA domain AAA_18 PF13238.1 KLO06419.1 - 4.5e-08 33.4 0.2 0.0098 16.1 0.0 3.8 3 1 0 3 3 2 2 AAA domain AAA_14 PF13173.1 KLO06419.1 - 3.9e-07 30.0 0.0 0.025 14.4 0.0 3.6 2 2 0 2 2 2 2 AAA domain AAA_25 PF13481.1 KLO06419.1 - 4.9e-07 29.3 0.6 0.039 13.3 0.3 3.5 2 1 0 2 2 2 2 AAA domain RNA_helicase PF00910.17 KLO06419.1 - 1.2e-06 28.6 0.0 0.11 12.6 0.0 3.0 3 0 0 3 3 2 2 RNA helicase AAA_33 PF13671.1 KLO06419.1 - 1.4e-05 25.0 0.0 0.057 13.2 0.0 2.6 2 0 0 2 2 2 2 AAA domain Zeta_toxin PF06414.7 KLO06419.1 - 3.6e-05 22.9 0.0 0.0072 15.4 0.0 2.6 2 0 0 2 2 2 1 Zeta toxin ABC_tran PF00005.22 KLO06419.1 - 4e-05 23.9 0.0 0.26 11.5 0.0 2.7 2 0 0 2 2 2 2 ABC transporter PD40 PF07676.7 KLO06419.1 - 4.5e-05 23.0 2.6 0.83 9.3 0.0 5.8 6 0 0 6 6 6 1 WD40-like Beta Propeller Repeat eIF2A PF08662.6 KLO06419.1 - 6.2e-05 22.7 0.0 0.06 13.0 0.0 3.6 2 1 1 4 4 3 1 Eukaryotic translation initiation factor eIF2A ADK PF00406.17 KLO06419.1 - 7.4e-05 22.6 0.2 0.053 13.3 0.0 3.1 3 1 0 3 3 3 1 Adenylate kinase Arch_ATPase PF01637.13 KLO06419.1 - 0.00025 20.8 0.0 0.11 12.1 0.0 2.8 3 0 0 3 3 2 1 Archaeal ATPase PPV_E1_C PF00519.12 KLO06419.1 - 0.00047 18.8 0.0 0.55 8.7 0.0 2.2 2 0 0 2 2 2 2 Papillomavirus helicase IstB_IS21 PF01695.12 KLO06419.1 - 0.00058 19.3 0.0 0.18 11.2 0.0 2.8 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_28 PF13521.1 KLO06419.1 - 0.00058 19.8 0.0 0.073 13.0 0.0 2.5 2 0 0 2 2 2 1 AAA domain FtsK_SpoIIIE PF01580.13 KLO06419.1 - 0.0011 18.5 0.0 0.52 9.7 0.0 3.1 3 0 0 3 3 3 1 FtsK/SpoIIIE family Parvo_NS1 PF01057.12 KLO06419.1 - 0.0017 17.2 0.0 0.59 8.9 0.0 2.3 2 0 0 2 2 2 1 Parvovirus non-structural protein NS1 APS_kinase PF01583.15 KLO06419.1 - 0.002 17.7 0.0 0.69 9.5 0.0 2.4 2 0 0 2 2 2 1 Adenylylsulphate kinase AAA_29 PF13555.1 KLO06419.1 - 0.0022 17.4 0.0 0.59 9.7 0.0 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain NTPase_1 PF03266.10 KLO06419.1 - 0.0023 17.6 0.0 1.9 8.1 0.0 2.4 2 0 0 2 2 2 1 NTPase MMR_HSR1 PF01926.18 KLO06419.1 - 0.0026 17.6 0.0 1.5 8.8 0.0 2.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_10 PF12846.2 KLO06419.1 - 0.0027 17.1 0.0 0.8 9.0 0.0 2.7 3 0 0 3 3 2 1 AAA-like domain DUF258 PF03193.11 KLO06419.1 - 0.0036 16.4 0.0 0.37 9.9 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_19 PF13245.1 KLO06419.1 - 0.006 16.3 0.0 1.5 8.6 0.0 2.8 2 0 0 2 2 2 1 Part of AAA domain PQQ_2 PF13360.1 KLO06419.1 - 0.0096 15.4 0.2 0.11 11.9 0.2 2.5 1 1 0 1 1 1 1 PQQ-like domain Nucleoporin_N PF08801.6 KLO06419.1 - 0.012 14.4 0.2 0.14 10.8 0.0 2.1 1 1 0 2 2 2 0 Nup133 N terminal like Nbas_N PF15492.1 KLO06419.1 - 0.013 14.5 1.2 23 3.9 0.1 4.3 2 1 0 3 3 3 0 Neuroblastoma-amplified sequence, N terminal Rad17 PF03215.10 KLO06419.1 - 0.02 13.5 0.0 5.4 5.5 0.0 2.9 3 0 0 3 3 3 0 Rad17 cell cycle checkpoint protein AAA_5 PF07728.9 KLO06419.1 - 0.021 14.5 0.0 2.3 7.9 0.0 2.5 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.16 KLO06419.1 - 0.026 13.6 0.0 7.8 5.5 0.0 2.8 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI MobB PF03205.9 KLO06419.1 - 0.029 14.0 0.0 2.3 7.9 0.0 2.7 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B DUF2075 PF09848.4 KLO06419.1 - 0.055 12.4 0.0 0.77 8.6 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) KAP_NTPase PF07693.9 KLO06419.1 - 0.066 12.1 5.1 8.2 5.3 1.4 3.1 2 1 0 3 3 3 0 KAP family P-loop domain AAA_24 PF13479.1 KLO06419.1 - 0.069 12.7 0.0 2.4 7.6 0.0 2.4 2 0 0 2 2 2 0 AAA domain ArgK PF03308.11 KLO06419.1 - 0.073 11.8 0.0 12 4.5 0.0 2.4 2 0 0 2 2 2 0 ArgK protein AAA_11 PF13086.1 KLO06419.1 - 0.081 12.4 0.0 4.3 6.8 0.0 2.4 2 0 0 2 2 2 0 AAA domain Guanylate_kin PF00625.16 KLO06419.1 - 0.12 11.7 0.0 8.4 5.7 0.0 2.5 2 0 0 2 2 2 0 Guanylate kinase DUF815 PF05673.8 KLO06419.1 - 0.13 11.2 0.0 5.5 5.8 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) RuvB_N PF05496.7 KLO06419.1 - 0.15 11.0 0.0 2.7 6.9 0.0 2.2 2 0 0 2 2 2 0 Holliday junction DNA helicase ruvB N-terminus AAA_PrkA PF08298.6 KLO06419.1 - 0.16 10.6 0.0 5.5 5.5 0.0 2.3 2 0 0 2 2 2 0 PrkA AAA domain ATP-synt_ab PF00006.20 KLO06419.1 - 0.16 11.4 0.0 14 5.0 0.0 2.4 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain KTI12 PF08433.5 KLO06419.1 - 0.28 10.3 0.0 7.2 5.7 0.0 2.3 2 0 0 2 2 2 0 Chromatin associated protein KTI12 Patatin PF01734.17 KLO06420.1 - 1.3e-13 51.3 0.1 3.4e-11 43.4 0.1 2.2 1 1 0 2 2 2 2 Patatin-like phospholipase ANTAR PF03861.9 KLO06420.1 - 0.081 12.5 0.0 0.15 11.6 0.0 1.4 1 0 0 1 1 1 0 ANTAR domain Dymeclin PF09742.4 KLO06420.1 - 0.15 10.1 0.0 0.18 9.9 0.0 1.1 1 0 0 1 1 1 0 Dyggve-Melchior-Clausen syndrome protein DUF2017 PF09438.5 KLO06426.1 - 0.021 14.3 0.0 0.04 13.4 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF2017) TSC22 PF01166.13 KLO06426.1 - 0.17 11.8 5.5 0.065 13.2 0.9 2.3 2 0 0 2 2 2 0 TSC-22/dip/bun family MFS_1 PF07690.11 KLO06430.1 - 4.6e-38 130.8 25.4 1.3e-37 129.3 16.4 2.2 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KLO06430.1 - 2e-19 69.5 2.1 2e-19 69.5 1.4 2.1 2 0 0 2 2 2 1 Sugar (and other) transporter ECSIT PF06239.6 KLO06431.1 - 0.061 12.1 0.2 0.16 10.8 0.2 1.6 1 0 0 1 1 1 0 Evolutionarily conserved signalling intermediate in Toll pathway DUF3518 PF12031.3 KLO06432.1 - 0.11 11.2 0.1 0.16 10.7 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3518) Ribosomal_S6 PF01250.12 KLO06435.1 - 1.8e-09 37.2 0.0 2.7e-09 36.7 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S6 SNase PF00565.12 KLO06436.1 - 2.9e-55 185.1 0.4 3.1e-19 69.2 0.0 6.6 5 2 0 5 5 5 5 Staphylococcal nuclease homologue TUDOR PF00567.19 KLO06436.1 - 1e-21 77.0 0.0 2.6e-21 75.7 0.0 1.6 1 0 0 1 1 1 1 Tudor domain ABC1 PF03109.11 KLO06437.1 - 3.5e-32 110.8 0.0 6.1e-32 110.0 0.0 1.4 1 0 0 1 1 1 1 ABC1 family RIO1 PF01163.17 KLO06437.1 - 0.00013 21.3 0.1 0.00058 19.2 0.0 1.9 2 0 0 2 2 2 1 RIO1 family PC4 PF02229.11 KLO06438.1 - 7.6e-24 82.7 0.2 1.3e-23 81.9 0.2 1.4 1 0 0 1 1 1 1 Transcriptional Coactivator p15 (PC4) RNA_pol_Rpc4 PF05132.9 KLO06438.1 - 0.033 14.1 3.6 0.044 13.7 2.5 1.2 1 0 0 1 1 1 0 RNA polymerase III RPC4 YqfQ PF14181.1 KLO06438.1 - 7.2 6.6 9.9 13 5.7 6.6 1.5 2 0 0 2 2 2 0 YqfQ-like protein HECT PF00632.20 KLO06439.1 - 1.5e-93 313.4 0.0 2.7e-93 312.6 0.0 1.4 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) DUF913 PF06025.7 KLO06439.1 - 1.5e-73 247.7 0.1 1.5e-73 247.7 0.1 4.8 4 1 1 5 5 5 1 Domain of Unknown Function (DUF913) DUF908 PF06012.7 KLO06439.1 - 2.2e-63 214.5 2.6 2.2e-63 214.5 1.8 2.3 2 0 0 2 2 2 1 Domain of Unknown Function (DUF908) DUF4414 PF14377.1 KLO06439.1 - 5.5e-29 100.2 6.8 5.5e-29 100.2 4.7 3.8 2 1 1 3 3 3 1 Domain of unknown function (DUF4414) UBA PF00627.26 KLO06439.1 - 7.8e-08 31.9 0.0 2e-07 30.6 0.0 1.8 1 0 0 1 1 1 1 UBA/TS-N domain RNA_pol_A_bac PF01000.21 KLO06440.1 - 3.7e-26 91.4 0.0 7.4e-26 90.5 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.19 KLO06440.1 - 4e-16 57.8 0.0 5.3e-16 57.4 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Fe_hyd_lg_C PF02906.9 KLO06441.1 - 5.5e-68 229.3 0.0 8.4e-68 228.6 0.0 1.3 1 0 0 1 1 1 1 Iron only hydrogenase large subunit, C-terminal domain SIN1 PF05422.7 KLO06442.1 - 9.2e-15 54.1 0.0 1.3e-14 53.6 0.0 1.2 1 0 0 1 1 1 1 Stress-activated map kinase interacting protein 1 (SIN1) Kinesin-relat_1 PF12711.2 KLO06443.1 - 0.17 12.3 4.0 1 9.8 0.0 3.0 3 0 0 3 3 3 0 Kinesin motor Prominin PF05478.6 KLO06446.1 - 0.022 12.3 0.2 0.034 11.7 0.1 1.2 1 0 0 1 1 1 0 Prominin F-box-like PF12937.2 KLO06448.1 - 2.6e-05 23.8 0.5 0.00014 21.5 0.2 2.4 2 0 0 2 2 2 1 F-box-like Herpes_UL25 PF01499.11 KLO06450.1 - 0.023 13.0 0.1 0.026 12.8 0.1 1.2 1 0 0 1 1 1 0 Herpesvirus UL25 family ASFV_L11L PF05293.6 KLO06450.1 - 0.43 10.7 2.6 1.1 9.4 0.3 2.2 1 1 1 2 2 2 0 African swine fever virus (ASFV) L11L protein MDFI PF15316.1 KLO06452.1 - 0.0087 16.0 2.9 0.0087 16.0 2.0 1.6 2 0 0 2 2 2 1 MyoD family inhibitor CTV_P6 PF06706.6 KLO06452.1 - 0.012 15.1 1.7 0.033 13.6 1.2 1.7 1 0 0 1 1 1 0 Citrus tristeza virus 6-kDa protein UPF0104 PF03706.8 KLO06452.1 - 0.091 12.0 0.7 0.3 10.3 0.6 1.6 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0104) TMEM154 PF15102.1 KLO06452.1 - 0.19 11.4 0.7 0.63 9.7 0.0 1.9 2 0 0 2 2 2 0 TMEM154 protein family Corona_S2 PF01601.11 KLO06452.1 - 0.34 8.9 4.1 0.53 8.3 2.8 1.2 1 0 0 1 1 1 0 Coronavirus S2 glycoprotein JmjC PF02373.17 KLO06454.1 - 0.011 15.9 0.0 0.55 10.4 0.0 2.6 2 0 0 2 2 2 0 JmjC domain, hydroxylase TT_ORF2 PF02957.10 KLO06454.1 - 0.22 12.2 0.1 0.22 12.2 0.1 5.5 6 0 0 6 6 6 0 TT viral ORF2 RPA_C PF08784.6 KLO06457.1 - 4.5e-06 27.0 0.0 7.6e-06 26.2 0.0 1.4 1 0 0 1 1 1 1 Replication protein A C terminal DNA_pol_A_exo1 PF01612.15 KLO06458.1 - 2.2e-11 43.5 0.0 8e-11 41.7 0.0 1.8 1 1 0 1 1 1 1 3'-5' exonuclease Spt5-NGN PF03439.8 KLO06458.1 - 5e-07 29.3 0.0 1.1e-06 28.2 0.0 1.6 1 0 0 1 1 1 1 Early transcription elongation factor of RNA pol II, NGN section KOW PF00467.24 KLO06458.1 - 3.2e-05 23.4 12.5 0.0016 18.0 0.9 4.3 4 0 0 4 4 4 2 KOW motif DUF4265 PF14085.1 KLO06458.1 - 0.14 11.9 0.0 0.4 10.4 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4265) Helicase_C PF00271.26 KLO06459.1 - 2e-16 59.5 0.0 1.1e-15 57.2 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.24 KLO06459.1 - 8.1e-15 54.7 0.0 1.7e-14 53.6 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase T4SS-DNA_transf PF02534.9 KLO06459.1 - 0.01 14.4 0.0 0.021 13.4 0.0 1.4 1 0 0 1 1 1 0 Type IV secretory system Conjugative DNA transfer ResIII PF04851.10 KLO06459.1 - 0.1 12.4 0.1 0.98 9.2 0.1 2.3 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit SLBP_RNA_bind PF15247.1 KLO06461.1 - 0.041 13.6 3.4 1.3 8.8 0.4 2.9 2 0 0 2 2 2 0 Histone RNA hairpin-binding protein RNA-binding domain HTH_Tnp_Tc3_2 PF01498.13 KLO06464.1 - 1.4e-05 25.0 0.1 1.9e-05 24.6 0.1 1.3 1 1 0 1 1 1 1 Transposase HTH_21 PF13276.1 KLO06464.1 - 0.078 12.9 0.0 0.1 12.6 0.0 1.3 1 1 0 1 1 1 0 HTH-like domain F-box PF00646.28 KLO06466.1 - 9.6e-06 25.1 0.1 3.4e-05 23.3 0.1 2.0 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 KLO06466.1 - 0.0045 16.6 0.0 0.014 15.1 0.0 1.9 1 0 0 1 1 1 1 F-box-like Fungal_trans PF04082.13 KLO06469.1 - 3.8e-11 42.3 0.7 3.8e-11 42.3 0.5 1.8 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KLO06469.1 - 0.002 18.0 9.6 0.0033 17.2 6.6 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF605 PF04652.11 KLO06469.1 - 0.0053 16.2 3.1 0.0053 16.2 2.2 3.9 4 1 0 4 4 4 1 Vta1 like Seryl_tRNA_N PF02403.17 KLO06469.1 - 0.24 11.4 3.5 0.17 11.8 0.7 2.0 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain F-box PF00646.28 KLO06471.1 - 0.0055 16.3 0.1 0.023 14.3 0.0 2.1 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.2 KLO06471.1 - 0.03 14.0 0.1 0.096 12.4 0.0 1.9 2 0 0 2 2 2 0 F-box-like F-box-like PF12937.2 KLO06472.1 - 0.034 13.8 0.0 0.11 12.2 0.0 1.9 2 0 0 2 2 2 0 F-box-like F-box PF00646.28 KLO06472.1 - 0.061 13.0 0.0 0.25 11.0 0.0 2.1 1 0 0 1 1 1 0 F-box domain DUF867 PF05908.6 KLO06472.1 - 0.094 11.7 0.0 0.16 11.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF867) F-box PF00646.28 KLO06478.1 - 0.00022 20.7 0.1 0.00043 19.8 0.1 1.5 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 KLO06478.1 - 0.02 14.5 0.5 0.032 13.9 0.0 1.6 2 0 0 2 2 2 0 F-box-like Fcf1 PF04900.7 KLO06479.1 - 2.3e-28 98.2 0.1 4.9e-28 97.1 0.0 1.6 1 0 0 1 1 1 1 Fcf1 Lipase_3 PF01764.20 KLO06480.1 - 1.4e-15 57.1 0.0 1.8e-15 56.7 0.0 1.2 1 0 0 1 1 1 1 Lipase (class 3) DUF2974 PF11187.3 KLO06480.1 - 0.0064 15.8 0.0 0.022 14.1 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF2974) Tcp11 PF05794.8 KLO06481.1 - 0.06 12.0 0.0 0.075 11.7 0.0 1.1 1 0 0 1 1 1 0 T-complex protein 11 Lipase_3 PF01764.20 KLO06482.1 - 4.1e-15 55.6 0.0 5.8e-15 55.1 0.0 1.2 1 0 0 1 1 1 1 Lipase (class 3) DUF2974 PF11187.3 KLO06482.1 - 0.0048 16.2 0.0 0.01 15.2 0.0 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF2974) Abhydrolase_6 PF12697.2 KLO06482.1 - 0.0064 16.3 0.0 0.008 16.0 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family zf-RVT PF13966.1 KLO06487.1 - 0.0011 19.2 0.1 0.002 18.3 0.1 1.5 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase RNase_H PF00075.19 KLO06487.1 - 0.0075 16.6 0.1 0.02 15.2 0.0 1.8 2 0 0 2 2 2 1 RNase H Kdo PF06293.9 KLO06490.1 - 0.00018 20.6 0.0 0.00035 19.7 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.15 KLO06490.1 - 0.023 14.2 0.0 0.037 13.6 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase Pkinase PF00069.20 KLO06490.1 - 0.054 12.6 0.0 0.088 11.9 0.0 1.2 1 0 0 1 1 1 0 Protein kinase domain zf-MYND PF01753.13 KLO06491.1 - 2.3e-07 30.5 6.1 2.3e-07 30.5 4.2 1.9 2 0 0 2 2 2 1 MYND finger Nup54 PF13874.1 KLO06491.1 - 0.0077 15.8 0.0 0.018 14.7 0.0 1.5 1 0 0 1 1 1 1 Nucleoporin complex subunit 54 PspA_IM30 PF04012.7 KLO06491.1 - 0.043 13.1 1.4 0.05 12.9 0.1 1.7 2 0 0 2 2 2 0 PspA/IM30 family EndIII_4Fe-2S PF10576.4 KLO06493.1 - 0.23 11.6 2.0 0.62 10.3 1.4 1.7 1 0 0 1 1 1 0 Iron-sulfur binding domain of endonuclease III zf-C3HC4_4 PF15227.1 KLO06495.1 - 0.00011 21.9 6.8 0.00078 19.2 4.7 2.3 1 1 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.20 KLO06495.1 - 0.0006 19.4 10.4 0.0032 17.0 7.2 2.3 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KLO06495.1 - 0.0015 18.5 9.6 0.0041 17.1 6.6 1.8 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KLO06495.1 - 0.0035 17.1 13.0 0.0091 15.8 9.0 1.8 1 0 0 1 1 1 1 Ring finger domain zf-RING_6 PF14835.1 KLO06495.1 - 0.0069 16.1 3.9 0.014 15.1 2.7 1.5 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-RING_UBOX PF13445.1 KLO06495.1 - 0.12 12.1 5.2 0.31 10.7 3.6 1.8 1 0 0 1 1 1 0 RING-type zinc-finger zf-RING_5 PF14634.1 KLO06495.1 - 1.4 8.7 12.6 3.9 7.2 8.7 1.8 1 1 0 1 1 1 0 zinc-RING finger domain zf-C3HC4_3 PF13920.1 KLO06495.1 - 1.7 8.3 10.5 5.2 6.8 7.3 1.9 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) PHD PF00628.24 KLO06496.1 - 0.065 12.9 12.0 0.082 12.6 5.1 2.4 2 0 0 2 2 2 0 PHD-finger zf-C3HC4 PF00097.20 KLO06497.1 - 4.8e-05 22.9 3.0 4.8e-05 22.9 2.1 1.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KLO06497.1 - 0.00036 20.2 9.3 0.0017 18.1 6.5 2.2 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4_4 PF15227.1 KLO06497.1 - 0.00052 19.8 4.5 0.00052 19.8 3.2 2.0 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.1 KLO06497.1 - 0.001 19.0 5.6 0.0025 17.7 3.9 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KLO06497.1 - 0.0025 17.4 5.0 0.0099 15.5 3.5 2.1 1 1 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 KLO06497.1 - 0.015 15.0 6.0 0.032 13.9 4.2 1.5 1 0 0 1 1 1 0 RING-type zinc-finger zf-C3HC4_3 PF13920.1 KLO06497.1 - 0.021 14.4 6.0 0.061 12.9 4.2 1.8 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-Nse PF11789.3 KLO06497.1 - 0.025 14.0 0.3 0.061 12.8 0.2 1.6 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit Etmic-2 PF06670.6 KLO06499.1 - 0.086 11.5 0.0 0.1 11.2 0.0 1.1 1 0 0 1 1 1 0 Microneme protein Etmic-2 PgaD PF13994.1 KLO06500.1 - 0.26 10.7 2.3 0.22 10.9 0.1 2.0 2 0 0 2 2 2 0 PgaD-like protein Neur_chan_memb PF02932.11 KLO06500.1 - 0.33 10.7 0.0 0.33 10.7 0.0 4.5 3 1 0 3 3 3 0 Neurotransmitter-gated ion-channel transmembrane region Amastin PF07344.6 KLO06500.1 - 0.73 9.4 4.8 1.2 8.6 3.3 1.3 1 0 0 1 1 1 0 Amastin surface glycoprotein SUR7 PF06687.7 KLO06500.1 - 8.4 5.8 18.6 2e+02 1.3 13.0 2.9 1 1 0 1 1 1 0 SUR7/PalI family Pkinase PF00069.20 KLO06501.1 - 1.2e-32 113.1 0.0 1.5e-32 112.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KLO06501.1 - 5.7e-14 51.8 0.0 7.1e-14 51.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 KLO06501.1 - 0.0013 18.5 0.0 0.95 9.1 0.0 2.3 2 0 0 2 2 2 2 Phosphotransferase enzyme family Herpes_UL49_5 PF05702.6 KLO06503.1 - 0.13 12.1 0.2 0.42 10.5 0.0 1.7 1 1 1 2 2 2 0 Herpesvirus UL49.5 envelope/tegument protein F-box-like PF12937.2 KLO06505.1 - 3e-07 30.0 1.4 2.2e-06 27.2 0.3 2.6 2 0 0 2 2 2 1 F-box-like DoxX_3 PF13781.1 KLO06506.1 - 4.3 7.7 7.7 0.29 11.4 1.0 2.2 2 1 1 3 3 3 0 DoxX-like family Transp_cyt_pur PF02133.10 KLO06507.1 - 1.4e-23 83.1 29.3 2.3e-23 82.5 20.3 1.3 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin DEAD PF00270.24 KLO06511.1 - 6.6e-45 152.6 0.0 1.2e-44 151.7 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF4217 PF13959.1 KLO06511.1 - 6.7e-24 83.2 0.3 1.3e-23 82.3 0.2 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) Helicase_C PF00271.26 KLO06511.1 - 4.1e-20 71.4 0.0 9.4e-20 70.2 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Helicase_C_2 PF13307.1 KLO06511.1 - 0.036 14.0 0.1 0.12 12.2 0.0 1.9 2 0 0 2 2 2 0 Helicase C-terminal domain p450 PF00067.17 KLO06513.1 - 7.1e-69 232.5 0.0 8.1e-69 232.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 KLO06514.1 - 1.5e-70 238.0 0.0 1.9e-70 237.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Pkinase PF00069.20 KLO06515.1 - 2.6e-61 207.0 0.0 4.6e-61 206.2 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KLO06515.1 - 9.4e-44 149.4 0.0 1.7e-43 148.5 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase DUF3543 PF12063.3 KLO06515.1 - 2.1e-21 76.2 0.0 3.9e-21 75.3 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3543) APH PF01636.18 KLO06515.1 - 0.0031 17.3 0.0 0.026 14.2 0.0 2.5 2 1 0 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.1 KLO06515.1 - 0.022 13.7 0.0 0.039 12.9 0.0 1.4 1 0 0 1 1 1 0 Kinase-like LssY_C PF14067.1 KLO06515.1 - 0.045 12.7 0.0 0.15 10.9 0.0 1.8 2 0 0 2 2 2 0 LssY C-terminus Cation_efflux PF01545.16 KLO06516.1 - 1.1e-09 37.8 1.1 1.7e-09 37.2 0.8 1.3 1 0 0 1 1 1 1 Cation efflux family Aminotran_1_2 PF00155.16 KLO06517.1 - 1.7e-40 139.1 0.0 2.1e-40 138.7 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II RNA_Me_trans PF04252.8 KLO06518.1 - 2.4e-37 128.2 0.0 3.1e-37 127.8 0.0 1.1 1 0 0 1 1 1 1 Predicted SAM-dependent RNA methyltransferase Chitin_synth_2 PF03142.10 KLO06519.1 - 2e-246 818.4 0.3 3e-246 817.9 0.2 1.2 1 0 0 1 1 1 1 Chitin synthase Myosin_head PF00063.16 KLO06519.1 - 2.3e-154 515.1 0.0 3.4e-154 514.5 0.0 1.3 1 0 0 1 1 1 1 Myosin head (motor domain) Cyt-b5 PF00173.23 KLO06519.1 - 2.6e-19 68.7 0.0 1.1e-12 47.6 0.0 2.6 1 1 1 2 2 2 2 Cytochrome b5-like Heme/Steroid binding domain DEK_C PF08766.6 KLO06519.1 - 2.1e-16 59.4 0.2 1.8e-15 56.4 0.1 2.3 2 0 0 2 2 2 1 DEK C terminal domain Glyco_trans_2_3 PF13632.1 KLO06519.1 - 7.8e-15 55.0 5.6 7.8e-15 55.0 3.9 2.7 3 1 0 3 3 3 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 KLO06519.1 - 1e-14 54.8 0.0 2e-11 44.1 0.0 2.6 2 0 0 2 2 2 2 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.21 KLO06519.1 - 9.5e-05 22.1 0.0 0.024 14.3 0.0 2.9 2 0 0 2 2 2 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.1 KLO06519.1 - 0.008 15.4 0.0 0.018 14.3 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 21 CLN3 PF02487.12 KLO06520.1 - 1.7e-56 191.7 11.5 1.3e-51 175.6 8.0 3.9 1 1 0 1 1 1 1 CLN3 protein DUF3611 PF12263.3 KLO06520.1 - 0.0047 16.3 0.0 0.014 14.8 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF3611) Abhydrolase_3 PF07859.8 KLO06521.1 - 6.4e-47 159.8 0.0 9.5e-47 159.2 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Chlorophyllase2 PF12740.2 KLO06521.1 - 0.00013 20.9 0.0 0.00018 20.5 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase enzyme DLH PF01738.13 KLO06521.1 - 0.021 14.1 0.2 0.036 13.3 0.0 1.4 2 0 0 2 2 2 0 Dienelactone hydrolase family Peptidase_S9 PF00326.16 KLO06521.1 - 0.035 13.3 0.0 4.1 6.5 0.0 2.5 3 0 0 3 3 3 0 Prolyl oligopeptidase family P_C PF06640.6 KLO06522.1 - 0.048 13.6 0.1 0.062 13.2 0.1 1.1 1 0 0 1 1 1 0 P protein C-terminus BTB PF00651.26 KLO06523.1 - 6.8e-06 26.0 0.1 1.7e-05 24.7 0.0 1.7 2 0 0 2 2 2 1 BTB/POZ domain Herpes_UL49_1 PF03117.9 KLO06523.1 - 0.032 13.3 0.0 0.066 12.3 0.0 1.5 1 0 0 1 1 1 0 UL49 family zf-MYND PF01753.13 KLO06524.1 - 5.6e-09 35.7 15.6 5.6e-09 35.7 10.8 2.0 2 0 0 2 2 2 1 MYND finger SRF-TF PF00319.13 KLO06525.1 - 6.8e-16 57.2 0.0 1.1e-15 56.6 0.0 1.3 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) DnaJ_CXXCXGXG PF00684.14 KLO06526.1 - 0.0038 17.2 3.1 1.8 8.6 0.3 2.5 2 0 0 2 2 2 2 DnaJ central domain zf-C3HC4_3 PF13920.1 KLO06526.1 - 4.2 7.1 6.6 14 5.4 0.1 2.6 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Peptidase_M56 PF05569.6 KLO06527.1 - 0.014 14.3 0.1 0.019 13.9 0.0 1.1 1 0 0 1 1 1 0 BlaR1 peptidase M56 DUF1191 PF06697.7 KLO06527.1 - 0.04 12.7 0.0 0.054 12.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1191) NicO PF03824.11 KLO06527.1 - 0.042 13.1 0.1 0.063 12.5 0.0 1.2 1 0 0 1 1 1 0 High-affinity nickel-transport protein DUF1469 PF07332.6 KLO06527.1 - 0.047 13.4 1.3 0.13 12.0 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1469) Pex14_N PF04695.8 KLO06528.1 - 0.35 10.9 5.6 0.67 9.9 3.9 1.5 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region BTB PF00651.26 KLO06529.1 - 1.8e-07 31.1 0.0 3.4e-07 30.2 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain XPA_N PF01286.13 KLO06529.1 - 5.5 6.7 6.7 23 4.7 0.1 3.1 2 1 1 3 3 3 0 XPA protein N-terminal BTB PF00651.26 KLO06530.1 - 2.8e-07 30.4 0.0 6.1e-07 29.4 0.0 1.6 1 0 0 1 1 1 1 BTB/POZ domain Skp1_POZ PF03931.10 KLO06530.1 - 0.0085 16.1 0.0 0.017 15.2 0.0 1.5 1 0 0 1 1 1 1 Skp1 family, tetramerisation domain Alpha-amylase PF00128.19 KLO06530.1 - 0.16 11.3 0.0 0.19 11.0 0.0 1.2 1 0 0 1 1 1 0 Alpha amylase, catalytic domain DnaJ PF00226.26 KLO06531.1 - 1.5e-10 40.6 0.4 3.6e-10 39.4 0.0 1.8 2 0 0 2 2 2 1 DnaJ domain TrbI PF03743.9 KLO06531.1 - 0.08 12.4 0.0 0.14 11.6 0.0 1.3 1 0 0 1 1 1 0 Bacterial conjugation TrbI-like protein Pex14_N PF04695.8 KLO06531.1 - 0.088 12.8 1.2 0.51 10.3 0.0 2.2 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region SR-25 PF10500.4 KLO06531.1 - 3.5 7.0 20.1 2 7.7 3.9 3.2 3 0 0 3 3 3 0 Nuclear RNA-splicing-associated protein BTB PF00651.26 KLO06532.1 - 1.7e-09 37.6 0.1 2.9e-09 36.8 0.1 1.3 1 0 0 1 1 1 1 BTB/POZ domain Orthopox_F14 PF06076.7 KLO06532.1 - 0.092 12.8 0.3 0.6 10.2 0.0 2.6 3 0 0 3 3 3 0 Orthopoxvirus F14 protein BTB PF00651.26 KLO06533.1 - 7.5e-07 29.1 0.0 1.3e-06 28.3 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain BTB PF00651.26 KLO06534.1 - 4.2e-08 33.1 0.0 7.2e-08 32.4 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain ORMDL PF04061.9 KLO06538.1 - 0.11 12.0 2.2 0.17 11.4 1.5 1.4 1 1 0 1 1 1 0 ORMDL family Sod_Cu PF00080.15 KLO06541.1 - 0.18 11.9 5.0 0.071 13.2 0.4 2.0 2 0 0 2 2 2 0 Copper/zinc superoxide dismutase (SODC) Macoilin PF09726.4 KLO06541.1 - 5 5.2 5.7 6.1 4.9 4.0 1.1 1 0 0 1 1 1 0 Transmembrane protein Glyco_hydro_16 PF00722.16 KLO06544.1 - 3e-22 78.7 0.1 5.2e-22 78.0 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 F-box-like PF12937.2 KLO06547.1 - 0.00049 19.7 0.2 0.0012 18.4 0.1 1.8 1 0 0 1 1 1 1 F-box-like SRF-TF PF00319.13 KLO06550.1 - 4e-20 70.7 0.1 6.5e-20 70.1 0.1 1.4 1 1 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) DUF128 PF01995.11 KLO06550.1 - 0.085 11.7 0.0 0.1 11.5 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function DUF128 BTB PF00651.26 KLO06554.1 - 2.2e-08 34.0 0.0 4.2e-08 33.1 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain Multi-haem_cyto PF13447.1 KLO06554.1 - 0.061 12.3 0.0 0.085 11.9 0.0 1.2 1 0 0 1 1 1 0 Seven times multi-haem cytochrome CxxCH BTB PF00651.26 KLO06555.1 - 5.5e-09 36.0 0.0 1.2e-08 34.9 0.0 1.6 1 0 0 1 1 1 1 BTB/POZ domain Skp1_POZ PF03931.10 KLO06555.1 - 0.14 12.3 0.2 0.37 10.9 0.0 1.8 2 0 0 2 2 2 0 Skp1 family, tetramerisation domain BCS1_N PF08740.6 KLO06556.1 - 3e-31 108.4 1.5 3e-31 108.4 1.0 2.5 2 1 0 2 2 1 1 BCS1 N terminal AAA PF00004.24 KLO06556.1 - 9.9e-15 54.9 0.0 1.6e-06 28.3 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) CAF-1_p150 PF11600.3 KLO06556.1 - 0.0002 20.7 51.0 0.0002 20.7 35.3 2.7 2 1 1 3 3 2 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal AAA_16 PF13191.1 KLO06556.1 - 0.00028 20.9 3.0 0.00057 19.9 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain DUF815 PF05673.8 KLO06556.1 - 0.0018 17.2 0.0 0.0037 16.2 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_29 PF13555.1 KLO06556.1 - 0.0025 17.3 0.1 0.017 14.6 0.0 2.2 2 0 0 2 2 2 1 P-loop containing region of AAA domain Viral_helicase1 PF01443.13 KLO06556.1 - 0.0054 16.2 0.0 0.012 15.1 0.0 1.6 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase AAA_17 PF13207.1 KLO06556.1 - 0.032 15.0 0.1 0.032 15.0 0.1 3.2 2 2 0 2 2 1 0 AAA domain AAA_19 PF13245.1 KLO06556.1 - 0.035 13.8 0.0 0.12 12.1 0.0 1.9 1 0 0 1 1 1 0 Part of AAA domain AAA_33 PF13671.1 KLO06556.1 - 0.052 13.4 0.0 0.052 13.4 0.0 2.3 2 0 0 2 2 1 0 AAA domain ABC_tran PF00005.22 KLO06556.1 - 0.24 11.7 0.1 0.24 11.7 0.1 2.5 2 1 0 2 2 2 0 ABC transporter AAA_11 PF13086.1 KLO06556.1 - 0.26 10.8 8.9 9.5 5.7 0.0 2.5 2 0 0 2 2 2 0 AAA domain MIP-T3 PF10243.4 KLO06556.1 - 3.4 6.0 50.5 1 7.7 31.4 2.1 2 0 0 2 2 2 0 Microtubule-binding protein MIP-T3 DDRGK PF09756.4 KLO06556.1 - 3.5 6.9 39.8 1.8e+02 1.4 0.0 2.7 2 0 0 2 2 2 0 DDRGK domain RR_TM4-6 PF06459.7 KLO06556.1 - 3.7 7.3 29.5 0.22 11.3 16.4 2.0 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 Hid1 PF12722.2 KLO06556.1 - 5.2 4.6 16.7 9.2 3.7 11.6 1.4 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein BTB PF00651.26 KLO06557.1 - 1.7e-07 31.1 0.0 4.5e-07 29.8 0.0 1.7 1 0 0 1 1 1 1 BTB/POZ domain Skp1_POZ PF03931.10 KLO06557.1 - 0.018 15.1 0.0 0.037 14.1 0.0 1.5 1 0 0 1 1 1 0 Skp1 family, tetramerisation domain BTB PF00651.26 KLO06558.1 - 1.4e-07 31.4 0.1 2.4e-07 30.7 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain Skp1_POZ PF03931.10 KLO06558.1 - 0.058 13.5 0.0 0.12 12.5 0.0 1.5 1 0 0 1 1 1 0 Skp1 family, tetramerisation domain HTH_23 PF13384.1 KLO06559.1 - 2.1e-05 24.0 0.0 4.1e-05 23.0 0.0 1.5 1 0 0 1 1 1 1 Homeodomain-like domain HTH_38 PF13936.1 KLO06559.1 - 4e-05 23.0 0.1 7.2e-05 22.2 0.1 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_29 PF13551.1 KLO06559.1 - 0.011 15.9 0.2 0.055 13.6 0.0 2.1 1 1 1 2 2 2 0 Winged helix-turn helix GerE PF00196.14 KLO06559.1 - 0.024 13.9 0.4 0.055 12.7 0.0 1.8 3 0 0 3 3 3 0 Bacterial regulatory proteins, luxR family HTH_28 PF13518.1 KLO06559.1 - 0.043 13.8 0.0 0.11 12.5 0.0 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain SpoIIID PF12116.3 KLO06559.1 - 0.053 13.4 0.1 0.12 12.3 0.1 1.7 1 1 0 1 1 1 0 Stage III sporulation protein D HTH_Tnp_ISL3 PF13542.1 KLO06559.1 - 0.12 11.5 0.1 0.23 10.6 0.1 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 HTH_24 PF13412.1 KLO06559.1 - 0.14 11.5 0.2 0.29 10.5 0.1 1.5 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding Aldo_ket_red PF00248.16 KLO06560.1 - 2e-66 223.7 0.0 2.2e-66 223.5 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Aldo_ket_red PF00248.16 KLO06561.1 - 5.9e-58 195.9 0.0 6.8e-58 195.7 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family BTB PF00651.26 KLO06564.1 - 0.00012 22.0 0.3 0.0018 18.2 0.2 2.4 1 1 0 1 1 1 1 BTB/POZ domain PAGK PF15284.1 KLO06566.1 - 0.38 10.5 1.6 0.54 10.0 0.5 1.7 2 0 0 2 2 2 0 Phage-encoded virulence factor RHH_1 PF01402.16 KLO06568.1 - 0.026 14.3 0.8 0.082 12.8 0.5 1.8 1 0 0 1 1 1 0 Ribbon-helix-helix protein, copG family MutS_III PF05192.13 KLO06570.1 - 0.012 15.3 0.2 0.023 14.5 0.1 1.4 1 0 0 1 1 1 0 MutS domain III RHH_1 PF01402.16 KLO06570.1 - 0.072 13.0 0.2 0.23 11.4 0.2 1.8 1 0 0 1 1 1 0 Ribbon-helix-helix protein, copG family Glyco_hydro_16 PF00722.16 KLO06572.1 - 1.9e-21 76.2 0.0 3.1e-21 75.5 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 4HBT PF03061.17 KLO06574.1 - 1.4e-09 37.9 0.0 2.3e-09 37.2 0.0 1.4 1 0 0 1 1 1 1 Thioesterase superfamily 4HBT PF03061.17 KLO06575.1 - 8.8e-08 32.1 0.1 1.8e-07 31.2 0.0 1.5 1 0 0 1 1 1 1 Thioesterase superfamily 4HBT_3 PF13622.1 KLO06575.1 - 0.0052 16.5 0.0 0.0055 16.4 0.0 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily ubiquitin PF00240.18 KLO06576.1 - 7e-24 83.0 0.3 7.8e-24 82.8 0.2 1.0 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 KLO06576.1 - 8.2e-15 54.2 0.1 8.9e-15 54.1 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like UN_NPL4 PF11543.3 KLO06576.1 - 0.00052 20.2 0.0 0.00075 19.7 0.0 1.3 1 1 0 1 1 1 1 Nuclear pore localisation protein NPL4 Ubiquitin_2 PF14560.1 KLO06576.1 - 0.0016 18.6 0.1 0.0016 18.6 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-like domain Telomere_Sde2 PF13019.1 KLO06576.1 - 0.012 15.3 0.0 0.012 15.2 0.0 1.0 1 0 0 1 1 1 0 Telomere stability and silencing Rad60-SLD_2 PF13881.1 KLO06576.1 - 0.09 12.6 0.1 0.24 11.3 0.0 1.7 1 1 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like ThiS PF02597.15 KLO06576.1 - 0.11 12.8 0.2 0.22 11.9 0.1 1.4 1 1 0 1 1 1 0 ThiS family F-box-like PF12937.2 KLO06577.1 - 2.7e-06 26.9 0.0 6.7e-06 25.7 0.0 1.7 1 1 0 1 1 1 1 F-box-like Methyltransf_23 PF13489.1 KLO06578.1 - 2.6e-13 49.9 0.0 3.9e-13 49.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KLO06578.1 - 1e-09 38.7 0.0 1.7e-09 38.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KLO06578.1 - 1.3e-09 37.7 0.0 2.5e-09 36.8 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KLO06578.1 - 9.8e-09 35.4 0.0 1.7e-08 34.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KLO06578.1 - 2.9e-06 27.8 0.0 7.1e-06 26.5 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KLO06578.1 - 4.7e-06 25.8 0.0 3e-05 23.2 0.0 2.0 1 1 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.7 KLO06578.1 - 6.4e-05 23.3 0.0 0.00014 22.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KLO06578.1 - 0.00012 22.1 0.0 0.00035 20.5 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain TPMT PF05724.6 KLO06578.1 - 0.094 12.1 0.0 0.21 11.0 0.0 1.6 1 1 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) DUF2353 PF09789.4 KLO06579.1 - 0.0073 15.5 19.5 0.065 12.4 8.0 3.1 2 1 1 3 3 3 1 Uncharacterized coiled-coil protein (DUF2353) DUF812 PF05667.6 KLO06579.1 - 0.07 11.6 17.8 0.12 10.8 12.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF812) Spc7 PF08317.6 KLO06579.1 - 0.83 8.2 24.0 0.009 14.7 1.1 2.7 2 1 0 2 2 2 0 Spc7 kinetochore protein HALZ PF02183.13 KLO06579.1 - 1.5 8.5 15.4 0.08 12.6 0.8 3.8 3 1 1 4 4 4 0 Homeobox associated leucine zipper IncA PF04156.9 KLO06579.1 - 2.3 7.7 30.9 0.038 13.5 2.1 3.1 1 1 1 2 2 2 0 IncA protein DUF2730 PF10805.3 KLO06579.1 - 6.2 6.6 10.0 11 5.7 0.1 4.3 5 0 0 5 5 5 0 Protein of unknown function (DUF2730) Methyltransf_23 PF13489.1 KLO06580.1 - 5.5e-12 45.6 0.0 8.8e-12 45.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KLO06580.1 - 1.6e-11 44.5 0.0 2.8e-11 43.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KLO06580.1 - 1.2e-10 41.1 0.0 1.8e-10 40.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KLO06580.1 - 2.1e-08 34.4 0.0 3.5e-08 33.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KLO06580.1 - 5.5e-07 28.9 0.0 1e-06 28.0 0.0 1.5 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.7 KLO06580.1 - 1.2e-05 25.6 0.0 2.3e-05 24.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KLO06580.1 - 0.00037 21.0 0.0 0.00071 20.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KLO06580.1 - 0.00073 19.5 0.0 0.002 18.1 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KLO06581.1 - 2.1e-13 50.3 0.0 3e-13 49.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KLO06581.1 - 1.2e-11 44.9 0.0 2.6e-11 43.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KLO06581.1 - 1.4e-09 37.7 0.0 5.3e-09 35.8 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KLO06581.1 - 3.4e-08 33.8 0.0 1.7e-07 31.6 0.0 2.1 2 1 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.13 KLO06581.1 - 5.1e-08 32.3 0.0 4.3e-07 29.2 0.0 2.3 1 1 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_18 PF12847.2 KLO06581.1 - 8.1e-05 23.1 0.0 0.00059 20.3 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KLO06581.1 - 0.00017 21.8 0.0 0.00035 20.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.10 KLO06581.1 - 0.0083 15.7 0.0 0.022 14.3 0.0 1.6 1 1 0 1 1 1 1 Hypothetical methyltransferase Methyltransf_26 PF13659.1 KLO06581.1 - 0.026 14.5 0.0 0.093 12.7 0.0 1.9 1 1 0 1 1 1 0 Methyltransferase domain MTS PF05175.9 KLO06581.1 - 0.15 11.4 0.0 0.28 10.5 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase small domain Methyltransf_23 PF13489.1 KLO06582.1 - 4e-12 46.1 0.0 5.5e-12 45.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KLO06582.1 - 2.1e-09 36.8 0.0 1.5e-08 34.0 0.0 2.2 2 1 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.1 KLO06582.1 - 4.1e-09 36.2 0.0 2.2e-08 33.8 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KLO06582.1 - 4.1e-09 36.8 0.0 7e-09 36.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KLO06582.1 - 1.5e-05 25.3 0.0 4.1e-05 23.9 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KLO06582.1 - 2.6e-05 24.7 0.0 0.00018 22.0 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KLO06582.1 - 2.6e-05 24.5 0.0 4.8e-05 23.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KLO06582.1 - 0.022 14.7 0.0 0.046 13.7 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain TPMT PF05724.6 KLO06582.1 - 0.13 11.6 0.0 0.19 11.1 0.0 1.2 1 0 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) 14-3-3 PF00244.15 KLO06583.1 - 3.4e-118 392.9 7.2 3.9e-118 392.7 5.0 1.0 1 0 0 1 1 1 1 14-3-3 protein TPR_12 PF13424.1 KLO06583.1 - 0.00017 21.4 1.7 0.045 13.6 0.1 2.6 2 1 0 2 2 2 2 Tetratricopeptide repeat DUF837 PF05769.6 KLO06583.1 - 0.051 13.1 4.7 0.74 9.3 0.2 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF837) TPR_8 PF13181.1 KLO06583.1 - 2 8.3 4.3 25 4.9 0.1 3.3 2 1 0 2 2 2 0 Tetratricopeptide repeat RasGAP PF00616.14 KLO06584.1 - 1.6e-28 99.6 0.0 5e-28 98.1 0.0 1.9 1 1 0 1 1 1 1 GTPase-activator protein for Ras-like GTPase CRAL_TRIO_2 PF13716.1 KLO06584.1 - 0.0029 17.5 1.1 0.0086 15.9 0.3 2.1 2 0 0 2 2 2 1 Divergent CRAL/TRIO domain Methyltransf_23 PF13489.1 KLO06586.1 - 5.5e-12 45.6 0.0 8.7e-12 45.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KLO06586.1 - 5e-11 42.4 0.0 1.1e-10 41.2 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KLO06586.1 - 8.3e-11 42.2 0.0 1.9e-10 41.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KLO06586.1 - 6.6e-08 31.9 0.0 3.1e-07 29.7 0.0 2.0 2 1 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.7 KLO06586.1 - 1.8e-06 28.3 0.0 4.6e-06 27.0 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KLO06586.1 - 7.5e-06 26.2 0.0 1.4e-05 25.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KLO06586.1 - 0.00037 21.0 0.0 0.0019 18.7 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KLO06586.1 - 0.0074 15.6 0.0 0.015 14.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_8 PF05148.10 KLO06586.1 - 0.041 13.5 0.0 0.082 12.5 0.0 1.6 1 1 0 1 1 1 0 Hypothetical methyltransferase PrmA PF06325.8 KLO06586.1 - 0.047 12.7 0.0 0.07 12.2 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) BTV_NS2 PF04514.7 KLO06586.1 - 0.083 11.7 0.0 0.12 11.2 0.0 1.1 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 Methyltransf_26 PF13659.1 KLO06586.1 - 0.11 12.5 0.0 0.39 10.7 0.0 1.9 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_23 PF13489.1 KLO06587.1 - 1.9e-08 34.1 0.0 2.6e-08 33.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KLO06587.1 - 1.9e-07 31.4 0.0 4.1e-07 30.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KLO06587.1 - 3.3e-05 23.5 0.0 0.00037 20.1 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KLO06587.1 - 0.0012 19.3 0.0 0.0031 17.9 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KLO06587.1 - 0.0031 17.8 0.0 0.011 16.1 0.0 1.9 2 1 0 2 2 2 1 Methyltransferase domain TPMT PF05724.6 KLO06587.1 - 0.033 13.6 0.0 0.049 13.0 0.0 1.2 1 0 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) CheR PF01739.13 KLO06587.1 - 0.047 12.9 0.0 0.071 12.3 0.0 1.4 1 0 0 1 1 1 0 CheR methyltransferase, SAM binding domain Methyltransf_18 PF12847.2 KLO06587.1 - 0.087 13.4 0.0 2.6 8.6 0.0 2.6 2 1 0 2 2 2 0 Methyltransferase domain Acetyltransf_3 PF13302.1 KLO06588.1 - 3.4e-08 33.7 0.0 4.7e-08 33.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain p450 PF00067.17 KLO06589.1 - 8.3e-71 238.8 0.0 1.1e-70 238.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 DUF515 PF04415.7 KLO06594.1 - 0.014 13.6 0.6 0.02 13.1 0.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF515) MFS_1 PF07690.11 KLO06595.1 - 1.5e-25 89.6 30.2 1.5e-25 89.6 20.9 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily p450 PF00067.17 KLO06596.1 - 7.4e-47 159.9 0.0 6.9e-42 143.5 0.0 2.0 2 0 0 2 2 2 2 Cytochrome P450 UPF0270 PF06794.7 KLO06598.1 - 0.088 12.5 0.0 0.13 12.0 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0270) TEA PF01285.13 KLO06600.1 - 9.3e-07 28.3 0.6 9.3e-07 28.3 0.4 1.8 2 0 0 2 2 2 1 TEA/ATTS domain family UEV PF05743.8 KLO06601.1 - 4.5e-35 119.9 0.0 7.3e-35 119.2 0.0 1.3 1 0 0 1 1 1 1 UEV domain Vps23_core PF09454.5 KLO06601.1 - 1.7e-26 91.6 0.4 3.1e-26 90.7 0.3 1.5 1 0 0 1 1 1 1 Vps23 core domain MSC PF09402.5 KLO06604.1 - 1.8e-56 191.2 0.0 2.7e-56 190.7 0.0 1.2 1 0 0 1 1 1 1 Man1-Src1p-C-terminal domain HeH PF12949.2 KLO06604.1 - 2.5e-08 33.3 0.0 1.7e-07 30.6 0.0 2.4 2 0 0 2 2 2 1 HeH/LEM domain Pkinase PF00069.20 KLO06605.1 - 4.3e-08 32.6 1.0 1.3e-06 27.7 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Kdo PF06293.9 KLO06605.1 - 0.02 13.9 1.4 0.048 12.7 0.2 2.1 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Cu_bind_like PF02298.12 KLO06606.1 - 7.8e-05 22.3 0.6 0.00018 21.2 0.4 1.6 1 0 0 1 1 1 1 Plastocyanin-like domain Copper-bind PF00127.15 KLO06606.1 - 0.004 17.3 0.2 0.009 16.2 0.2 1.6 1 0 0 1 1 1 1 Copper binding proteins, plastocyanin/azurin family Pyr_redox_2 PF07992.9 KLO06608.1 - 7.1e-07 29.3 0.0 6.4e-06 26.1 0.0 2.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 KLO06608.1 - 0.0017 18.1 0.0 2.6 7.7 0.0 2.6 2 0 0 2 2 2 2 FAD-NAD(P)-binding Pyr_redox_3 PF13738.1 KLO06608.1 - 0.15 12.1 0.3 21 5.0 0.0 2.3 1 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HATPase_c PF02518.21 KLO06609.1 - 0.044 13.4 0.0 0.1 12.3 0.0 1.6 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HTH_23 PF13384.1 KLO06613.1 - 0.00015 21.2 0.0 0.0002 20.9 0.0 1.2 1 0 0 1 1 1 1 Homeodomain-like domain HTH_29 PF13551.1 KLO06613.1 - 0.00015 21.8 0.0 0.00024 21.1 0.0 1.4 1 1 0 1 1 1 1 Winged helix-turn helix GerE PF00196.14 KLO06613.1 - 0.0021 17.3 0.0 0.0056 15.9 0.0 1.6 2 0 0 2 2 2 1 Bacterial regulatory proteins, luxR family HTH_38 PF13936.1 KLO06613.1 - 0.0043 16.5 0.2 0.0098 15.4 0.1 1.6 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_7 PF02796.10 KLO06613.1 - 0.0046 16.8 0.0 0.93 9.4 0.0 2.3 2 0 0 2 2 2 2 Helix-turn-helix domain of resolvase HTH_28 PF13518.1 KLO06613.1 - 0.0092 15.9 0.0 0.015 15.3 0.0 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain ABC_membrane PF00664.18 KLO06617.1 - 2.6e-66 223.8 22.2 3.9e-37 128.1 5.7 2.3 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 KLO06617.1 - 1.3e-60 203.6 0.0 3.1e-29 101.9 0.0 2.5 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.14 KLO06617.1 - 1.9e-17 63.2 0.3 1.4e-06 27.7 0.1 4.3 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 KLO06617.1 - 1.7e-12 47.9 0.0 0.055 13.4 0.0 4.2 4 0 0 4 4 4 4 AAA domain AAA_17 PF13207.1 KLO06617.1 - 2.3e-10 41.3 0.3 0.00017 22.4 0.0 2.9 2 1 0 2 2 2 2 AAA domain AAA_10 PF12846.2 KLO06617.1 - 2.5e-09 36.9 0.5 0.085 12.2 0.0 4.5 4 1 0 5 5 5 2 AAA-like domain AAA_29 PF13555.1 KLO06617.1 - 3e-08 33.0 0.4 0.0077 15.7 0.1 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.1 KLO06617.1 - 6.9e-08 32.7 2.1 0.0053 16.9 0.0 4.2 2 2 0 2 2 2 2 AAA domain AAA_25 PF13481.1 KLO06617.1 - 1.2e-07 31.3 2.2 0.03 13.7 0.3 4.0 3 1 0 3 3 3 2 AAA domain AAA_18 PF13238.1 KLO06617.1 - 3.9e-07 30.4 0.0 0.014 15.6 0.0 2.7 2 0 0 2 2 2 2 AAA domain SbcCD_C PF13558.1 KLO06617.1 - 5.4e-07 29.4 0.5 0.023 14.6 0.0 3.4 2 1 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_16 PF13191.1 KLO06617.1 - 6.1e-07 29.6 7.7 0.0005 20.1 0.1 3.6 2 1 0 2 2 2 2 AAA ATPase domain ABC_ATPase PF09818.4 KLO06617.1 - 7.9e-07 28.0 1.5 0.024 13.2 0.0 3.0 4 0 0 4 4 4 2 Predicted ATPase of the ABC class IstB_IS21 PF01695.12 KLO06617.1 - 3e-06 26.7 0.3 3.2 7.1 0.0 4.4 4 0 0 4 4 4 1 IstB-like ATP binding protein Sigma54_activ_2 PF14532.1 KLO06617.1 - 1.8e-05 24.7 0.1 1.2 9.1 0.0 3.7 3 0 0 3 3 3 1 Sigma-54 interaction domain AAA_28 PF13521.1 KLO06617.1 - 2.4e-05 24.3 0.9 0.66 9.9 0.2 3.5 2 1 0 2 2 2 2 AAA domain FtsK_SpoIIIE PF01580.13 KLO06617.1 - 5.2e-05 22.8 0.0 0.26 10.7 0.0 2.5 2 0 0 2 2 2 2 FtsK/SpoIIIE family AAA_30 PF13604.1 KLO06617.1 - 5.2e-05 22.9 0.5 0.17 11.4 0.0 4.3 4 1 0 4 4 4 1 AAA domain DUF258 PF03193.11 KLO06617.1 - 0.00016 20.8 0.0 0.18 10.9 0.0 2.6 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_33 PF13671.1 KLO06617.1 - 0.00024 21.0 0.0 1.1 9.1 0.0 2.9 2 0 0 2 2 2 2 AAA domain Zeta_toxin PF06414.7 KLO06617.1 - 0.0004 19.5 0.0 0.92 8.5 0.0 2.4 2 0 0 2 2 2 2 Zeta toxin DUF87 PF01935.12 KLO06617.1 - 0.00044 20.1 1.6 0.074 12.8 0.0 2.9 2 1 0 2 2 2 1 Domain of unknown function DUF87 AAA_5 PF07728.9 KLO06617.1 - 0.00056 19.6 0.0 1.4 8.6 0.0 3.3 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) APS_kinase PF01583.15 KLO06617.1 - 0.0014 18.3 0.1 1.6 8.3 0.0 2.5 2 0 0 2 2 2 1 Adenylylsulphate kinase G-alpha PF00503.15 KLO06617.1 - 0.0026 16.5 0.0 0.11 11.2 0.0 2.4 2 0 0 2 2 2 1 G-protein alpha subunit CbiA PF01656.18 KLO06617.1 - 0.0063 15.9 0.0 0.59 9.5 0.0 2.7 2 0 0 2 2 2 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_23 PF13476.1 KLO06617.1 - 0.0075 16.6 0.0 0.91 9.8 0.0 2.3 2 0 0 2 2 2 1 AAA domain DUF2075 PF09848.4 KLO06617.1 - 0.0076 15.2 0.1 1.4 7.7 0.0 2.5 3 0 0 3 3 3 1 Uncharacterized conserved protein (DUF2075) Mg_chelatase PF01078.16 KLO06617.1 - 0.0084 15.2 0.0 5 6.2 0.0 2.6 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI MobB PF03205.9 KLO06617.1 - 0.0096 15.6 0.3 2.2 8.0 0.0 2.6 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B NACHT PF05729.7 KLO06617.1 - 0.015 15.0 0.1 5.9 6.5 0.0 2.7 2 0 0 2 2 2 0 NACHT domain CoaE PF01121.15 KLO06617.1 - 0.016 14.5 0.1 5.5 6.3 0.0 2.7 2 0 0 2 2 2 0 Dephospho-CoA kinase PRK PF00485.13 KLO06617.1 - 0.02 14.4 0.0 3.7 7.0 0.0 2.5 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family Sigma54_activat PF00158.21 KLO06617.1 - 0.033 13.6 0.0 5.7 6.3 0.0 2.5 2 0 0 2 2 2 0 Sigma-54 interaction domain RNA_helicase PF00910.17 KLO06617.1 - 0.034 14.3 0.0 14 5.8 0.0 2.6 2 0 0 2 2 2 0 RNA helicase CobU PF02283.11 KLO06617.1 - 0.034 13.5 0.1 1.4 8.3 0.0 2.6 2 0 0 2 2 2 0 Cobinamide kinase / cobinamide phosphate guanyltransferase KaiC PF06745.8 KLO06617.1 - 0.045 12.8 0.0 6.4 5.8 0.0 2.7 2 0 0 2 2 2 0 KaiC AAA_14 PF13173.1 KLO06617.1 - 0.075 12.9 0.0 4.6 7.1 0.0 3.0 3 0 0 3 3 2 0 AAA domain Miro PF08477.8 KLO06617.1 - 0.089 13.2 0.0 18 5.8 0.0 2.6 2 0 0 2 2 2 0 Miro-like protein PhoH PF02562.11 KLO06617.1 - 0.11 11.7 0.7 17 4.5 0.0 3.3 3 0 0 3 3 3 0 PhoH-like protein MMR_HSR1 PF01926.18 KLO06617.1 - 0.12 12.3 0.0 8 6.4 0.0 3.1 3 0 0 3 3 3 0 50S ribosome-binding GTPase NB-ARC PF00931.17 KLO06617.1 - 0.13 11.1 0.0 2.5 6.8 0.0 2.2 2 0 0 2 2 2 0 NB-ARC domain CobA_CobO_BtuR PF02572.10 KLO06617.1 - 0.16 11.5 1.4 3 7.4 0.0 3.0 3 0 0 3 3 3 0 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP AAA_13 PF13166.1 KLO06617.1 - 0.36 9.2 0.0 11 4.3 0.0 2.2 2 0 0 2 2 2 0 AAA domain Transcrip_act PF04949.8 KLO06618.1 - 0.002 17.7 1.7 0.0032 17.1 1.2 1.2 1 0 0 1 1 1 1 Transcriptional activator Molybdopterin PF00384.17 KLO06619.1 - 8.8e-71 238.8 0.0 3.9e-70 236.7 0.0 1.8 1 1 0 1 1 1 1 Molybdopterin oxidoreductase Fer2_4 PF13510.1 KLO06619.1 - 2.7e-19 68.7 0.1 8.1e-19 67.2 0.1 1.9 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain NADH-G_4Fe-4S_3 PF10588.4 KLO06619.1 - 5.1e-19 67.2 0.1 1.3e-18 65.9 0.1 1.8 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region DUF1982 PF09326.6 KLO06619.1 - 9.2e-17 60.9 0.1 2.8e-16 59.3 0.0 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF1982) Fer2 PF00111.22 KLO06619.1 - 4.7e-09 35.8 0.4 4.7e-09 35.8 0.3 2.1 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain TPP_enzyme_M PF00205.17 KLO06619.1 - 0.013 15.2 0.0 0.32 10.7 0.0 2.4 2 0 0 2 2 2 0 Thiamine pyrophosphate enzyme, central domain PNP_UDP_1 PF01048.15 KLO06620.1 - 5.8e-38 130.1 0.0 8.8e-38 129.5 0.0 1.3 1 1 0 1 1 1 1 Phosphorylase superfamily DUF4401 PF14351.1 KLO06621.1 - 0.0028 16.7 0.1 0.0034 16.4 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4401) CbtB PF09489.5 KLO06621.1 - 0.047 13.6 1.8 0.059 13.2 0.2 1.9 2 0 0 2 2 2 0 Probable cobalt transporter subunit (CbtB) DUF2207 PF09972.4 KLO06621.1 - 0.19 10.3 0.5 0.29 9.6 0.4 1.4 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) AA_permease_2 PF13520.1 KLO06622.1 - 5.3e-37 127.3 38.2 7.1e-37 126.9 26.5 1.2 1 0 0 1 1 1 1 Amino acid permease DUF3329 PF11808.3 KLO06622.1 - 5.3 7.2 7.5 3.4 7.8 0.2 3.6 3 0 0 3 3 3 0 Domain of unknown function (DUF3329) SUR7 PF06687.7 KLO06624.1 - 1.1e-15 57.7 15.1 2.6e-15 56.5 10.5 1.6 1 1 0 1 1 1 1 SUR7/PalI family DUF1230 PF06799.6 KLO06624.1 - 0.14 12.0 0.5 0.26 11.1 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1230) FLILHELTA PF10306.4 KLO06624.1 - 0.15 12.1 0.2 0.32 11.0 0.2 1.7 1 1 0 1 1 1 0 Hypothetical protein FLILHELTA TPT PF03151.11 KLO06624.1 - 1.3 8.6 12.1 12 5.4 6.0 2.8 1 1 1 2 2 2 0 Triose-phosphate Transporter family TadE PF07811.7 KLO06624.1 - 1.9 8.4 0.0 1.9 8.4 0.0 3.7 4 0 0 4 4 4 0 TadE-like protein Claudin_2 PF13903.1 KLO06624.1 - 3.4 7.3 20.2 2.3 7.8 11.1 2.3 1 1 2 3 3 3 0 PMP-22/EMP/MP20/Claudin tight junction Ribosomal_L27e PF01777.13 KLO06625.1 - 1e-32 112.0 5.4 1.4e-32 111.6 3.7 1.2 1 0 0 1 1 1 1 Ribosomal L27e protein family KOW PF00467.24 KLO06625.1 - 6.5e-05 22.4 0.9 0.00018 21.0 0.6 1.8 1 0 0 1 1 1 1 KOW motif SUI1 PF01253.17 KLO06625.1 - 0.096 12.5 0.0 0.3 10.9 0.0 1.8 1 0 0 1 1 1 0 Translation initiation factor SUI1 DEAD PF00270.24 KLO06626.1 - 5.6e-18 64.9 0.0 1.6e-17 63.4 0.0 1.8 3 0 0 3 3 3 1 DEAD/DEAH box helicase PrgH PF09480.5 KLO06626.1 - 0.0022 16.8 0.0 0.14 11.0 0.0 2.1 1 1 0 2 2 2 2 Type III secretion system protein PrgH-EprH (PrgH) Helicase_C PF00271.26 KLO06626.1 - 0.058 13.2 0.0 0.17 11.7 0.0 1.7 2 0 0 2 2 2 0 Helicase conserved C-terminal domain SecA_DEAD PF07517.9 KLO06626.1 - 0.06 12.6 0.0 0.11 11.7 0.0 1.4 1 0 0 1 1 1 0 SecA DEAD-like domain zf-C2H2 PF00096.21 KLO06627.1 - 1e-05 25.5 17.6 0.023 14.9 0.6 3.8 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KLO06627.1 - 0.0016 18.5 12.8 0.095 13.0 0.7 3.7 3 0 0 3 3 3 3 C2H2-type zinc finger IBR PF01485.16 KLO06627.1 - 0.08 12.8 10.7 0.25 11.2 1.3 2.5 1 1 1 2 2 2 0 IBR domain C1_4 PF07975.7 KLO06627.1 - 0.08 12.9 2.4 0.17 11.8 0.1 2.5 2 0 0 2 2 2 0 TFIIH C1-like domain zf-H2C2_2 PF13465.1 KLO06627.1 - 4.6 7.7 12.4 6.5 7.2 1.7 3.6 4 0 0 4 4 4 0 Zinc-finger double domain MFS_1 PF07690.11 KLO06628.1 - 8.7e-27 93.7 31.8 8.9e-22 77.2 5.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1 PF07690.11 KLO06630.1 - 1.4e-23 83.1 31.2 1.8e-17 63.0 5.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KLO06630.1 - 2.6e-07 29.5 17.5 3.6e-07 29.1 12.1 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter zf-C2H2_4 PF13894.1 KLO06632.1 - 1.3e-06 28.3 13.6 0.0099 16.1 0.4 3.8 4 0 0 4 4 4 2 C2H2-type zinc finger zf-C2H2 PF00096.21 KLO06632.1 - 0.00024 21.2 3.2 0.007 16.6 0.2 4.1 5 0 0 5 5 5 2 Zinc finger, C2H2 type RPAP2_Rtr1 PF04181.8 KLO06632.1 - 0.016 15.3 0.6 0.03 14.4 0.4 1.5 1 0 0 1 1 1 0 Rtr1/RPAP2 family MSA-2c PF12238.3 KLO06632.1 - 0.13 11.8 0.1 0.21 11.2 0.1 1.3 1 0 0 1 1 1 0 Merozoite surface antigen 2c zf-C2H2_6 PF13912.1 KLO06632.1 - 0.5 10.3 3.3 13 5.8 0.2 2.9 3 0 0 3 3 3 0 C2H2-type zinc finger zf-H2C2_5 PF13909.1 KLO06632.1 - 3.3 8.1 9.1 0.38 11.0 0.4 3.3 3 0 0 3 3 3 0 C2H2-type zinc-finger domain PQ-loop PF04193.9 KLO06633.1 - 1e-21 76.2 0.8 9.6e-10 37.8 0.0 2.7 2 0 0 2 2 2 2 PQ loop repeat NMN_transporter PF04973.7 KLO06633.1 - 3.1 7.2 6.3 0.52 9.7 0.3 2.2 2 1 0 2 2 2 0 Nicotinamide mononucleotide transporter BTB PF00651.26 KLO06635.1 - 0.01 15.7 0.0 0.013 15.4 0.0 1.2 1 0 0 1 1 1 0 BTB/POZ domain MFS_1 PF07690.11 KLO06636.1 - 5.9e-26 91.0 21.5 5.9e-26 91.0 14.9 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KLO06636.1 - 2.1e-07 29.8 14.7 2.9e-07 29.4 10.2 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter ORC6 PF05460.8 KLO06637.1 - 0.058 12.4 0.0 0.058 12.4 0.0 3.3 2 1 1 3 3 3 0 Origin recognition complex subunit 6 (ORC6) DUF475 PF04332.10 KLO06637.1 - 0.16 11.4 0.0 0.24 10.9 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF475) zf-MYND PF01753.13 KLO06638.1 - 1.1e-09 38.0 16.0 3.3e-09 36.4 11.1 1.9 1 0 0 1 1 1 1 MYND finger zf-Mss51 PF13824.1 KLO06638.1 - 0.12 12.2 4.0 0.29 11.0 2.8 1.6 1 0 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 TP2 PF01254.13 KLO06639.1 - 4 7.7 10.3 1.1 9.5 4.9 1.6 1 1 1 2 2 2 0 Nuclear transition protein 2 DUF676 PF05057.9 KLO06640.1 - 2.3e-05 23.7 0.1 6.4e-05 22.3 0.0 1.7 2 0 0 2 2 2 1 Putative serine esterase (DUF676) Abhydrolase_6 PF12697.2 KLO06640.1 - 6.7e-05 22.8 0.0 0.0001 22.2 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.8 KLO06640.1 - 8.8e-05 22.1 0.0 0.00017 21.2 0.0 1.4 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_5 PF12695.2 KLO06640.1 - 0.0014 18.4 0.0 0.0024 17.6 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family RRM_1 PF00076.17 KLO06640.1 - 0.0024 17.4 0.1 0.0064 16.0 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Cutinase PF01083.17 KLO06640.1 - 0.024 14.3 0.0 0.069 12.8 0.0 1.6 1 1 0 1 1 1 0 Cutinase RRM_6 PF14259.1 KLO06640.1 - 0.042 13.8 0.0 0.14 12.1 0.0 2.0 2 0 0 2 2 2 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) DUF676 PF05057.9 KLO06641.1 - 0.0071 15.6 0.0 0.0081 15.4 0.0 1.1 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_6 PF12697.2 KLO06641.1 - 0.038 13.8 0.0 0.05 13.4 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family DUF3089 PF11288.3 KLO06641.1 - 0.15 11.2 0.0 0.19 10.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3089) PGAP1 PF07819.8 KLO06642.1 - 9.3e-08 31.9 0.0 1.5e-07 31.2 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_6 PF12697.2 KLO06642.1 - 4.9e-05 23.3 0.0 9.7e-05 22.3 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF676 PF05057.9 KLO06642.1 - 0.00013 21.3 0.0 0.00022 20.5 0.0 1.4 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Thioesterase PF00975.15 KLO06642.1 - 0.0022 18.2 0.0 0.0053 17.0 0.0 1.6 2 0 0 2 2 2 1 Thioesterase domain Abhydrolase_5 PF12695.2 KLO06642.1 - 0.0053 16.5 0.0 0.0087 15.8 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family LCAT PF02450.10 KLO06642.1 - 0.027 13.4 0.0 0.054 12.4 0.0 1.4 2 0 0 2 2 2 0 Lecithin:cholesterol acyltransferase Lipase_3 PF01764.20 KLO06642.1 - 0.029 14.0 0.0 0.2 11.2 0.0 2.1 2 0 0 2 2 2 0 Lipase (class 3) DUF726 PF05277.7 KLO06642.1 - 0.078 11.8 0.0 0.15 10.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF726) Cutinase PF01083.17 KLO06642.1 - 0.083 12.6 0.0 0.14 11.8 0.0 1.4 1 0 0 1 1 1 0 Cutinase Abhydrolase_6 PF12697.2 KLO06643.1 - 0.00034 20.5 0.0 0.00039 20.3 0.0 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KLO06643.1 - 0.01 15.6 0.0 0.012 15.3 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF3089 PF11288.3 KLO06643.1 - 0.025 13.7 0.0 0.028 13.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3089) PGAP1 PF07819.8 KLO06643.1 - 0.027 14.0 0.0 0.036 13.6 0.0 1.2 1 0 0 1 1 1 0 PGAP1-like protein DUF676 PF05057.9 KLO06643.1 - 0.059 12.6 0.0 0.07 12.4 0.0 1.1 1 0 0 1 1 1 0 Putative serine esterase (DUF676) PHF5 PF03660.9 KLO06644.1 - 8.9e-50 167.2 8.0 1e-49 167.0 5.5 1.0 1 0 0 1 1 1 1 PHF5-like protein Prok-RING_1 PF14446.1 KLO06644.1 - 0.8 9.4 12.8 7.4 6.3 0.2 2.7 2 1 0 2 2 2 0 Prokaryotic RING finger family 1 PHD PF00628.24 KLO06644.1 - 1.1 9.0 12.6 6.4 6.5 8.1 2.4 2 1 1 3 3 3 0 PHD-finger DZR PF12773.2 KLO06644.1 - 1.2 9.0 13.3 0.8 9.5 5.1 2.8 1 1 1 2 2 2 0 Double zinc ribbon Peptidase_S10 PF00450.17 KLO06645.1 - 6.6e-63 213.2 0.0 4.9e-62 210.4 0.0 2.2 1 1 0 1 1 1 1 Serine carboxypeptidase DAP10 PF07213.6 KLO06646.1 - 0.017 14.8 0.1 0.29 10.9 0.0 2.4 2 0 0 2 2 2 0 DAP10 membrane protein Amnionless PF14828.1 KLO06646.1 - 0.17 10.3 0.0 0.22 9.9 0.0 1.1 1 0 0 1 1 1 0 Amnionless Evr1_Alr PF04777.8 KLO06647.1 - 2.8e-26 91.2 0.0 3.5e-26 90.9 0.0 1.1 1 0 0 1 1 1 1 Erv1 / Alr family FAD_binding_3 PF01494.14 KLO06648.1 - 3.6e-22 78.9 0.0 9.4e-11 41.3 0.0 2.3 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.19 KLO06648.1 - 1.6e-06 27.3 0.0 0.0023 16.9 0.0 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 KLO06648.1 - 4.3e-06 25.8 0.3 0.00065 18.7 0.0 2.6 3 0 0 3 3 3 1 Lycopene cyclase protein NAD_binding_9 PF13454.1 KLO06648.1 - 4.9e-05 23.1 0.1 0.00017 21.3 0.1 1.9 1 1 0 1 1 1 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 KLO06648.1 - 6.7e-05 22.8 0.0 0.00012 22.0 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 KLO06648.1 - 0.00059 18.5 0.2 0.015 13.9 0.1 2.5 3 0 0 3 3 3 1 Tryptophan halogenase SE PF08491.5 KLO06648.1 - 0.00075 18.4 0.0 0.0012 17.7 0.0 1.2 1 0 0 1 1 1 1 Squalene epoxidase Pyr_redox_3 PF13738.1 KLO06648.1 - 0.0014 18.7 0.2 0.0069 16.4 0.1 2.2 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KLO06648.1 - 0.0048 16.8 0.1 0.015 15.3 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 KLO06648.1 - 0.02 15.3 0.3 0.41 11.0 0.0 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 KLO06648.1 - 0.025 13.0 0.4 0.044 12.2 0.3 1.3 1 0 0 1 1 1 0 HI0933-like protein Thi4 PF01946.12 KLO06648.1 - 0.037 13.1 0.2 0.072 12.1 0.1 1.3 1 0 0 1 1 1 0 Thi4 family FAD_binding_2 PF00890.19 KLO06648.1 - 0.1 11.4 1.3 0.2 10.4 0.9 1.5 1 0 0 1 1 1 0 FAD binding domain GIDA PF01134.17 KLO06648.1 - 0.16 10.7 0.0 0.29 9.9 0.0 1.4 1 0 0 1 1 1 0 Glucose inhibited division protein A WD40 PF00400.27 KLO06649.1 - 9.4e-06 25.3 0.6 0.61 10.0 0.1 4.0 2 1 1 3 3 3 2 WD domain, G-beta repeat CPSF_A PF03178.10 KLO06649.1 - 0.0055 15.8 0.4 0.21 10.6 0.0 2.7 2 1 0 3 3 3 1 CPSF A subunit region Nup160 PF11715.3 KLO06649.1 - 0.023 12.8 0.0 0.038 12.1 0.0 1.3 1 0 0 1 1 1 0 Nucleoporin Nup120/160 PBP1_TM PF14812.1 KLO06649.1 - 0.83 9.9 4.3 0.24 11.7 0.3 2.0 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Smr PF01713.16 KLO06650.1 - 2e-08 34.3 0.2 1.2e-07 31.8 0.1 2.3 2 0 0 2 2 2 1 Smr domain DUF1771 PF08590.5 KLO06650.1 - 9.5e-05 22.3 4.8 9.5e-05 22.3 3.3 2.1 2 0 0 2 2 1 1 Domain of unknown function (DUF1771) AAA_13 PF13166.1 KLO06650.1 - 0.0019 16.7 3.1 0.0019 16.7 2.2 2.2 1 1 1 2 2 2 1 AAA domain GAS PF13851.1 KLO06650.1 - 0.014 14.5 19.5 0.3 10.2 5.7 2.5 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding HOOK PF05622.7 KLO06650.1 - 0.079 10.7 17.3 0.12 10.1 12.0 1.2 1 0 0 1 1 1 0 HOOK protein IncA PF04156.9 KLO06650.1 - 0.29 10.7 22.7 0.028 14.0 12.6 1.6 2 0 0 2 2 2 0 IncA protein TarH PF02203.10 KLO06650.1 - 0.73 9.6 6.5 0.12 12.1 0.9 2.1 1 1 1 2 2 2 0 Tar ligand binding domain homologue ERM PF00769.14 KLO06650.1 - 0.8 9.1 28.0 0.015 14.8 14.2 1.8 2 0 0 2 2 2 0 Ezrin/radixin/moesin family PTPlike_phytase PF14566.1 KLO06650.1 - 1.6 8.7 5.5 0.59 10.1 1.9 1.8 2 0 0 2 2 2 0 Inositol hexakisphosphate TPR_MLP1_2 PF07926.7 KLO06650.1 - 3.2 7.5 16.9 5.5 6.7 6.2 2.7 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein Spc7 PF08317.6 KLO06650.1 - 4.6 5.8 15.0 0.19 10.3 3.8 2.0 1 1 0 1 1 1 0 Spc7 kinetochore protein V_ATPase_I PF01496.14 KLO06650.1 - 7.6 4.2 11.3 1.8 6.3 5.8 1.4 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family DUF342 PF03961.8 KLO06650.1 - 8.9 4.5 10.2 17 3.6 7.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF342) Zip PF02535.17 KLO06653.1 - 1.6e-47 162.1 11.4 3.7e-47 160.8 7.9 1.5 1 1 0 1 1 1 1 ZIP Zinc transporter Zip PF02535.17 KLO06654.1 - 6.4e-52 176.5 10.6 7.7e-52 176.2 7.3 1.0 1 0 0 1 1 1 1 ZIP Zinc transporter Chromate_transp PF02417.10 KLO06654.1 - 1.2 8.7 12.0 0.084 12.4 0.7 2.6 3 0 0 3 3 3 0 Chromate transporter DUF2781 PF10914.3 KLO06655.1 - 6.7e-17 61.6 2.2 1.3e-16 60.7 1.5 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF2781) zf-HIT PF04438.11 KLO06656.1 - 2.9e-07 29.9 9.1 4.6e-07 29.3 6.3 1.3 1 0 0 1 1 1 1 HIT zinc finger zf-Mss51 PF13824.1 KLO06656.1 - 1.6 8.6 4.3 3.6 7.5 2.9 1.6 1 0 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 DUF4199 PF13858.1 KLO06657.1 - 4.4 7.2 14.9 4.4 7.2 4.5 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF4199) p450 PF00067.17 KLO06658.1 - 0.00025 19.7 0.0 0.00027 19.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 UvrD_C_2 PF13538.1 KLO06659.1 - 4.8e-05 23.4 0.0 0.00015 21.8 0.0 1.8 1 1 0 1 1 1 1 UvrD-like helicase C-terminal domain PIF1 PF05970.9 KLO06660.1 - 7.4e-14 51.4 0.0 7.9e-14 51.3 0.0 1.0 1 0 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.1 KLO06660.1 - 4.8e-07 29.5 0.0 5.7e-07 29.3 0.0 1.1 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 KLO06660.1 - 0.042 13.8 0.0 0.044 13.7 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain NB-ARC PF00931.17 KLO06660.1 - 0.056 12.3 0.0 0.075 11.8 0.0 1.1 1 0 0 1 1 1 0 NB-ARC domain AAA_22 PF13401.1 KLO06660.1 - 0.072 13.2 0.1 0.13 12.4 0.0 1.6 1 1 0 1 1 1 0 AAA domain Mg_chelatase PF01078.16 KLO06660.1 - 0.096 11.8 0.0 0.11 11.6 0.0 1.1 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI CbiA PF01656.18 KLO06660.1 - 0.13 11.6 0.0 0.14 11.5 0.0 1.1 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain GST_N_3 PF13417.1 KLO06663.1 - 2.8e-19 69.0 0.0 6.2e-19 68.0 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 KLO06663.1 - 6.9e-15 54.8 0.0 1.3e-14 53.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 KLO06663.1 - 0.021 14.9 0.0 0.042 14.0 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain p450 PF00067.17 KLO06664.1 - 9.3e-67 225.5 0.0 1.2e-66 225.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Mis12 PF05859.7 KLO06665.1 - 4.3e-15 55.7 0.0 6.9e-15 55.1 0.0 1.3 1 0 0 1 1 1 1 Mis12 protein DUF1479 PF07350.7 KLO06666.1 - 2.9e-128 427.9 0.0 3.4e-128 427.7 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1479) PhyH PF05721.8 KLO06666.1 - 0.0066 16.5 0.1 1 9.3 0.1 2.7 2 1 0 2 2 2 2 Phytanoyl-CoA dioxygenase (PhyH) Prefoldin_2 PF01920.15 KLO06667.1 - 3.8e-16 58.7 5.9 4.6e-16 58.4 4.1 1.1 1 0 0 1 1 1 1 Prefoldin subunit DUF3391 PF11871.3 KLO06667.1 - 3.3e-05 24.0 0.1 5e-05 23.5 0.1 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF3391) Tropomyosin_1 PF12718.2 KLO06667.1 - 0.0038 17.0 4.3 0.0038 17.0 2.9 1.9 2 0 0 2 2 2 1 Tropomyosin like TMF_DNA_bd PF12329.3 KLO06667.1 - 0.066 13.0 4.7 0.14 11.9 3.3 1.5 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding Formyl_trans_N PF00551.14 KLO06667.1 - 0.074 12.5 0.1 0.094 12.2 0.1 1.1 1 0 0 1 1 1 0 Formyl transferase FliD_C PF07195.7 KLO06667.1 - 0.078 12.2 3.2 0.25 10.6 0.8 1.9 1 1 1 2 2 2 0 Flagellar hook-associated protein 2 C-terminus CorA PF01544.13 KLO06667.1 - 0.24 10.3 2.4 3.5 6.5 0.2 2.0 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein NBP1 PF08537.5 KLO06667.1 - 0.37 9.9 4.9 4.3 6.4 0.4 2.0 2 0 0 2 2 2 0 Fungal Nap binding protein NBP1 Prefoldin PF02996.12 KLO06667.1 - 0.72 9.5 6.1 0.43 10.2 1.7 2.1 1 1 1 2 2 2 0 Prefoldin subunit Seryl_tRNA_N PF02403.17 KLO06667.1 - 1 9.4 7.8 9.2 6.3 5.4 2.0 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain Fib_alpha PF08702.5 KLO06667.1 - 1.6 8.8 6.4 4.9 7.2 1.1 2.0 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family EF-hand_5 PF13202.1 KLO06668.1 - 1.2e-09 37.0 0.4 0.00049 19.3 0.1 2.7 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.1 KLO06668.1 - 7.1e-09 34.8 0.4 0.00021 20.9 0.0 2.5 2 0 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.1 KLO06668.1 - 1.4e-08 34.7 3.8 1.7e-08 34.5 0.5 2.2 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.27 KLO06668.1 - 7.5e-08 31.1 0.4 0.0029 16.7 0.0 2.4 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.1 KLO06668.1 - 0.00067 19.2 0.7 0.012 15.1 0.3 2.3 1 1 1 2 2 2 2 EF-hand domain pair DUF1524 PF07510.6 KLO06668.1 - 0.15 11.9 0.1 0.15 11.9 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1524) DUF2489 PF10675.4 KLO06668.1 - 0.42 10.2 6.1 2.4 7.8 4.2 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF2489) Dopey_N PF04118.9 KLO06669.1 - 1.7e-107 358.7 0.0 2.2e-106 355.1 0.0 2.5 2 0 0 2 2 2 1 Dopey, N-terminal INO80_Ies4 PF08193.6 KLO06670.1 - 0.0067 16.3 0.8 0.0067 16.3 0.6 3.8 2 2 2 4 4 4 1 INO80 complex subunit Ies4 AT_hook PF02178.14 KLO06672.1 - 0.16 11.7 0.2 0.16 11.7 0.2 2.7 3 0 0 3 3 3 0 AT hook motif DUF566 PF04484.7 KLO06672.1 - 7.5 5.9 9.1 9.8 5.5 6.3 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF566) JAB PF01398.16 KLO06673.1 - 2.6e-10 40.0 0.0 4.5e-10 39.2 0.0 1.3 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease HAD_2 PF13419.1 KLO06674.1 - 1.7e-26 93.4 0.0 3.6e-26 92.4 0.0 1.6 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 KLO06674.1 - 0.00015 21.4 0.0 0.00033 20.2 0.0 1.6 1 0 0 1 1 1 1 HAD-hyrolase-like DUF2608 PF11019.3 KLO06674.1 - 0.071 12.0 0.0 0.14 11.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2608) HAD_2 PF13419.1 KLO06675.1 - 1.3e-22 80.8 0.1 3.6e-22 79.4 0.0 1.7 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 KLO06675.1 - 0.0014 18.2 0.0 0.0028 17.3 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like FSH1 PF03959.8 KLO06676.1 - 4.2e-46 157.0 0.0 5.4e-46 156.7 0.0 1.1 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_5 PF12695.2 KLO06676.1 - 1.2e-08 34.8 0.0 2.1e-08 34.0 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KLO06676.1 - 2e-05 24.6 0.1 0.013 15.3 0.0 2.4 1 1 1 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KLO06676.1 - 0.00011 21.8 0.0 0.24 10.9 0.0 2.3 2 0 0 2 2 2 2 alpha/beta hydrolase fold DLH PF01738.13 KLO06676.1 - 0.00038 19.8 0.0 0.00067 19.0 0.0 1.3 1 0 0 1 1 1 1 Dienelactone hydrolase family Peptidase_S9 PF00326.16 KLO06676.1 - 0.0096 15.1 0.0 0.029 13.5 0.0 1.7 2 0 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_2 PF02230.11 KLO06676.1 - 0.14 11.5 0.8 1.9 7.8 0.4 2.6 2 1 0 2 2 2 0 Phospholipase/Carboxylesterase CHCH PF06747.8 KLO06677.1 - 9e-08 31.8 4.0 1.8e-07 30.9 2.8 1.5 1 0 0 1 1 1 1 CHCH domain FNIP_N PF14636.1 KLO06677.1 - 0.051 14.0 0.2 0.098 13.1 0.2 1.4 1 0 0 1 1 1 0 Folliculin-interacting protein N-terminus GCK PF07802.6 KLO06677.1 - 0.21 11.7 2.0 0.35 11.0 1.4 1.4 1 0 0 1 1 1 0 GCK domain DUF2151 PF10221.4 KLO06677.1 - 0.8 7.7 2.8 0.41 8.7 0.5 1.5 2 0 0 2 2 2 0 Cell cycle and development regulator Nro1 PF12753.2 KLO06677.1 - 1.5 7.7 5.8 1.5 7.6 0.1 2.0 2 0 0 2 2 2 0 Nuclear pore complex subunit Nro1 DUF1932 PF09130.6 KLO06678.1 - 8.6e-09 35.0 0.0 1.8e-08 34.0 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1932) F420_oxidored PF03807.12 KLO06678.1 - 0.00018 21.8 0.0 0.00069 20.0 0.0 2.0 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.10 KLO06678.1 - 0.012 15.5 0.0 0.078 12.8 0.0 2.3 2 1 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase Spore_YhaL PF14147.1 KLO06679.1 - 8.1 5.9 5.9 5.2 6.5 0.0 2.9 3 0 0 3 3 3 0 Sporulation protein YhaL F-box-like PF12937.2 KLO06680.1 - 7.5e-06 25.5 0.7 0.00021 20.9 0.0 2.6 2 0 0 2 2 2 1 F-box-like Bclx_interact PF08945.5 KLO06680.1 - 0.089 12.3 0.5 0.27 10.8 0.3 1.8 1 0 0 1 1 1 0 Bcl-x interacting, BH3 domain CAP_assoc_N PF14504.1 KLO06680.1 - 0.32 10.7 1.1 0.53 10.0 0.8 1.2 1 0 0 1 1 1 0 CAP-associated N-terminal F-box-like PF12937.2 KLO06681.1 - 0.00059 19.5 0.1 0.0015 18.2 0.1 1.7 1 0 0 1 1 1 1 F-box-like F-box-like PF12937.2 KLO06682.1 - 1.4e-05 24.7 1.0 2.9e-05 23.7 0.1 2.0 2 0 0 2 2 2 1 F-box-like Cytokin_check_N PF10407.4 KLO06682.1 - 0.021 14.4 0.0 0.042 13.4 0.0 1.5 1 0 0 1 1 1 0 Cdc14 phosphatase binding protein N-terminus LRR_4 PF12799.2 KLO06682.1 - 0.7 9.5 3.5 3.7 7.2 0.0 3.4 3 1 1 4 4 4 0 Leucine Rich repeats (2 copies) F-box-like PF12937.2 KLO06683.1 - 1.7e-07 30.8 2.8 2.4e-06 27.1 0.2 3.2 3 0 0 3 3 3 1 F-box-like LRR_4 PF12799.2 KLO06683.1 - 0.14 11.8 1.6 3.5 7.3 0.1 3.7 3 2 1 4 4 4 0 Leucine Rich repeats (2 copies) CbiC PF02570.10 KLO06683.1 - 0.2 11.0 0.0 0.32 10.4 0.0 1.2 1 0 0 1 1 1 0 Precorrin-8X methylmutase Dr_adhesin PF12393.3 KLO06685.1 - 0.52 10.4 3.4 4 7.6 0.2 2.2 2 0 0 2 2 2 0 Dr family adhesin F-box-like PF12937.2 KLO06687.1 - 5.6e-09 35.5 0.4 3e-08 33.2 0.0 2.4 2 1 0 2 2 2 1 F-box-like LRR_8 PF13855.1 KLO06687.1 - 0.00039 20.0 1.6 0.083 12.6 0.2 3.0 3 0 0 3 3 3 2 Leucine rich repeat LRR_6 PF13516.1 KLO06687.1 - 0.0039 17.1 3.5 0.4 10.8 0.0 4.3 4 0 0 4 4 4 1 Leucine Rich repeat LRR_4 PF12799.2 KLO06687.1 - 0.26 10.9 5.2 3.5 7.3 0.4 4.1 5 0 0 5 5 5 0 Leucine Rich repeats (2 copies) LRR_7 PF13504.1 KLO06687.1 - 1 9.8 9.0 1.3e+02 3.4 0.0 5.6 5 0 0 5 5 5 0 Leucine rich repeat F-box PF00646.28 KLO06687.1 - 1.5 8.5 6.3 19 5.0 0.1 3.6 4 0 0 4 4 4 0 F-box domain zf-C3HC4 PF00097.20 KLO06688.1 - 2.1e-06 27.2 3.1 2.1e-06 27.2 2.1 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KLO06688.1 - 2.6e-06 27.3 3.4 2.6e-06 27.3 2.3 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KLO06688.1 - 5.4e-06 26.1 10.8 2.5e-05 24.0 7.5 1.9 1 1 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.1 KLO06688.1 - 2.9e-05 23.6 2.0 7.8e-05 22.3 1.4 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_6 PF14835.1 KLO06688.1 - 0.00048 19.8 1.4 0.00048 19.8 1.0 1.9 2 0 0 2 2 2 1 zf-RING of BARD1-type protein zf-C3HC4_4 PF15227.1 KLO06688.1 - 0.0005 19.8 6.9 0.00083 19.1 2.7 2.4 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.1 KLO06688.1 - 0.00086 18.9 10.0 0.0029 17.2 3.9 2.4 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 KLO06688.1 - 0.0049 16.5 10.2 0.084 12.5 3.0 2.3 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) FANCL_C PF11793.3 KLO06688.1 - 0.13 12.2 6.7 3.2 7.7 3.2 2.5 2 1 0 2 2 2 0 FANCL C-terminal domain zf-rbx1 PF12678.2 KLO06688.1 - 0.23 11.5 7.8 0.63 10.2 3.8 2.4 2 1 0 2 2 2 0 RING-H2 zinc finger Ribosomal_L32p PF01783.18 KLO06688.1 - 0.24 11.5 0.2 0.24 11.5 0.2 2.2 2 0 0 2 2 2 0 Ribosomal L32p protein family HALZ PF02183.13 KLO06688.1 - 0.53 10.0 2.8 1.3 8.7 1.3 2.0 2 0 0 2 2 2 0 Homeobox associated leucine zipper Vps39_2 PF10367.4 KLO06688.1 - 1.1 9.4 3.9 5.2 7.2 0.1 2.3 2 0 0 2 2 2 0 Vacuolar sorting protein 39 domain 2 zf-MIZ PF02891.15 KLO06688.1 - 1.6 8.3 8.8 1.3 8.5 2.4 2.3 2 0 0 2 2 2 0 MIZ/SP-RING zinc finger FYVE PF01363.16 KLO06688.1 - 1.7 8.5 6.5 7.9 6.4 4.5 2.1 1 1 0 1 1 1 0 FYVE zinc finger ECH PF00378.15 KLO06689.1 - 2.5e-79 265.8 0.2 3.1e-79 265.5 0.1 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family ECH_C PF13766.1 KLO06689.1 - 0.033 14.3 0.0 0.088 12.9 0.0 1.7 2 0 0 2 2 2 0 2-enoyl-CoA Hydratase C-terminal region AARP2CN PF08142.7 KLO06690.1 - 0.025 14.0 0.0 0.08 12.4 0.1 1.7 2 0 0 2 2 2 0 AARP2CN (NUC121) domain Abhydrolase_3 PF07859.8 KLO06691.1 - 9.5e-21 74.3 0.4 2.8e-19 69.5 0.3 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold DUF2424 PF10340.4 KLO06691.1 - 8.7e-14 50.9 0.0 5e-09 35.2 0.0 3.0 3 0 0 3 3 3 3 Protein of unknown function (DUF2424) Abhydrolase_5 PF12695.2 KLO06691.1 - 0.0084 15.8 0.0 0.012 15.3 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Pap_E4 PF02711.9 KLO06693.1 - 8 7.3 11.4 8.2 7.3 1.3 2.9 2 0 0 2 2 2 0 E4 protein F-box-like PF12937.2 KLO06694.1 - 4.7e-09 35.8 0.2 1.9e-08 33.8 0.0 2.2 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 KLO06694.1 - 0.00071 19.1 0.1 0.0025 17.4 0.0 2.0 1 0 0 1 1 1 1 F-box domain MFS_1 PF07690.11 KLO06695.1 - 1.6e-21 76.4 37.6 1.6e-21 76.4 26.1 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF4328 PF14219.1 KLO06695.1 - 0.23 10.7 3.7 0.57 9.4 0.7 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4328) Pkinase PF00069.20 KLO06696.1 - 3.4e-44 150.9 0.0 5.7e-44 150.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KLO06696.1 - 2e-38 131.9 0.0 2.8e-38 131.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase PACT_coil_coil PF10495.4 KLO06696.1 - 7.6e-10 38.5 10.6 0.00065 19.5 0.1 3.8 1 1 2 3 3 3 3 Pericentrin-AKAP-450 domain of centrosomal targeting protein Kinase-like PF14531.1 KLO06696.1 - 1.2e-07 30.9 0.0 2.2e-07 30.1 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 KLO06696.1 - 0.0011 18.0 0.0 0.0054 15.8 0.0 2.0 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.4 KLO06696.1 - 0.038 13.3 0.0 0.091 12.0 0.0 1.6 1 1 0 1 1 1 0 PhoP regulatory network protein YrbL RIO1 PF01163.17 KLO06696.1 - 0.05 12.9 0.0 0.16 11.2 0.0 1.9 2 0 0 2 2 2 0 RIO1 family CysG_dimeriser PF10414.4 KLO06696.1 - 0.15 11.5 1.8 2.5 7.6 0.0 3.2 3 0 0 3 3 3 0 Sirohaem synthase dimerisation region CaATP_NAI PF12515.3 KLO06696.1 - 2 7.9 7.7 7.3 6.1 0.2 3.3 3 0 0 3 3 3 0 Ca2+-ATPase N terminal autoinhibitory domain adh_short PF00106.20 KLO06698.1 - 2.9e-11 43.5 5.6 5.9e-09 36.0 2.4 2.2 2 0 0 2 2 2 2 short chain dehydrogenase KR PF08659.5 KLO06698.1 - 2.8e-05 23.8 2.3 2.8e-05 23.8 1.6 1.6 2 0 0 2 2 2 1 KR domain NAD_binding_10 PF13460.1 KLO06698.1 - 0.00036 20.5 1.1 0.015 15.3 0.4 2.3 2 0 0 2 2 2 1 NADH(P)-binding THF_DHG_CYH_C PF02882.14 KLO06698.1 - 0.00082 18.4 0.2 0.0013 17.8 0.1 1.2 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain adh_short_C2 PF13561.1 KLO06698.1 - 0.0018 18.1 0.2 0.45 10.2 0.0 2.2 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase 3HCDH_N PF02737.13 KLO06698.1 - 0.0064 16.1 1.3 0.0099 15.5 0.9 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Multi_Drug_Res PF00893.14 KLO06699.1 - 2.8 8.4 9.8 7.5 7.0 0.8 3.1 2 1 1 3 3 3 0 Small Multidrug Resistance protein Pro-kuma_activ PF09286.6 KLO06700.1 - 3.5e-40 137.3 0.5 5.4e-39 133.4 0.1 2.4 3 0 0 3 3 3 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.17 KLO06700.1 - 1.5e-12 47.2 2.1 2.3e-12 46.6 1.4 1.3 1 0 0 1 1 1 1 Subtilase family DNA_pol_A_exo1 PF01612.15 KLO06701.1 - 1.8e-12 47.0 0.0 1e-05 25.1 0.0 2.5 3 0 0 3 3 3 2 3'-5' exonuclease DUF912 PF06024.7 KLO06702.1 - 0.019 15.0 0.3 0.25 11.4 0.0 2.1 2 0 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) SCIMP PF15050.1 KLO06702.1 - 0.035 14.0 1.5 0.086 12.7 0.0 2.0 2 0 0 2 2 2 0 SCIMP protein DUF4577 PF15145.1 KLO06702.1 - 1.1 9.2 3.5 0.51 10.2 0.2 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4577) IncA PF04156.9 KLO06702.1 - 8.7 5.8 10.5 8 6.0 1.0 2.1 2 0 0 2 2 2 0 IncA protein F-box-like PF12937.2 KLO06703.1 - 0.00061 19.4 0.2 0.0018 17.9 0.1 1.9 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.2 KLO06703.1 - 8.4 6.1 9.8 2.2 7.9 0.0 4.1 4 0 0 4 4 4 0 Leucine Rich repeats (2 copies) F-box-like PF12937.2 KLO06704.1 - 3.1e-07 30.0 0.0 1.1e-06 28.2 0.0 2.0 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KLO06704.1 - 0.061 12.9 1.0 1.3 8.8 0.7 2.8 1 1 0 1 1 1 0 F-box domain F-box-like PF12937.2 KLO06706.1 - 1.3e-08 34.3 0.1 3.8e-08 32.9 0.0 1.8 1 0 0 1 1 1 1 F-box-like LRR_1 PF00560.28 KLO06706.1 - 2.4 8.5 5.2 54 4.4 0.1 5.0 5 0 0 5 5 5 0 Leucine Rich Repeat F-box-like PF12937.2 KLO06707.1 - 3.5e-07 29.8 0.0 9.5e-07 28.4 0.0 1.8 1 0 0 1 1 1 1 F-box-like PIF1 PF05970.9 KLO06708.1 - 1.8e-24 86.3 0.0 2.2e-24 86.0 0.0 1.0 1 0 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.1 KLO06708.1 - 2.1e-11 43.7 0.0 2.4e-10 40.3 0.0 2.0 1 1 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.13 KLO06708.1 - 0.00058 19.4 0.3 0.0017 17.9 0.2 1.7 1 1 0 1 1 1 1 Viral (Superfamily 1) RNA helicase AAA_19 PF13245.1 KLO06708.1 - 0.0025 17.5 0.0 0.0053 16.4 0.0 1.5 2 0 0 2 2 2 1 Part of AAA domain Helicase_RecD PF05127.9 KLO06708.1 - 0.0045 16.6 0.1 0.17 11.5 0.1 2.1 1 1 1 2 2 2 2 Helicase AAA_11 PF13086.1 KLO06708.1 - 0.0072 15.9 0.9 0.42 10.1 0.0 2.7 2 1 1 3 3 3 1 AAA domain AAA_16 PF13191.1 KLO06708.1 - 0.013 15.5 0.1 0.019 14.9 0.0 1.3 1 1 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.1 KLO06708.1 - 0.024 14.7 0.1 0.064 13.4 0.1 1.7 1 1 0 1 1 1 0 AAA domain AAA PF00004.24 KLO06708.1 - 0.052 13.7 0.0 0.074 13.2 0.0 1.2 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Torsin PF06309.6 KLO06708.1 - 0.085 12.7 0.0 0.14 12.0 0.0 1.3 1 0 0 1 1 1 0 Torsin Helitron_like_N PF14214.1 KLO06710.1 - 6.9e-19 68.2 0.2 3.4e-18 66.0 0.0 2.0 2 0 0 2 2 2 1 Helitron helicase-like domain at N-terminus F-box-like PF12937.2 KLO06713.1 - 3.1e-09 36.4 0.0 9.2e-09 34.9 0.0 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KLO06713.1 - 0.0033 17.0 0.0 0.018 14.6 0.0 2.3 1 1 0 1 1 1 1 F-box domain F-box-like PF12937.2 KLO06715.1 - 1.4e-06 27.9 0.0 6e-06 25.8 0.0 2.1 1 0 0 1 1 1 1 F-box-like F-box-like PF12937.2 KLO06716.1 - 1.9e-08 33.8 0.0 4.9e-08 32.5 0.0 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KLO06716.1 - 0.0072 15.9 0.6 0.098 12.3 0.4 2.5 1 1 0 1 1 1 1 F-box domain DUF4375 PF14300.1 KLO06717.1 - 0.12 12.3 0.6 1.2 9.1 0.5 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4375) D5_N PF08706.6 KLO06717.1 - 0.97 9.5 5.6 0.96 9.5 0.3 2.6 2 0 0 2 2 2 0 D5 N terminal like Tet_JBP PF12851.2 KLO06718.1 - 1.5e-12 47.1 0.0 1.9e-12 46.7 0.0 1.1 1 0 0 1 1 1 1 Oxygenase domain of the 2OGFeDO superfamily SQS_PSY PF00494.14 KLO06719.1 - 7.4e-37 127.0 0.0 9.7e-37 126.6 0.0 1.2 1 0 0 1 1 1 1 Squalene/phytoene synthase Pkinase PF00069.20 KLO06720.1 - 7.5e-08 31.8 0.4 7e-07 28.6 0.3 2.1 1 1 0 1 1 1 1 Protein kinase domain Kdo PF06293.9 KLO06720.1 - 0.013 14.5 0.0 0.028 13.5 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_Tyr PF07714.12 KLO06720.1 - 0.086 11.8 0.0 0.17 10.9 0.0 1.4 1 0 0 1 1 1 0 Protein tyrosine kinase Pkinase PF00069.20 KLO06721.1 - 6.8e-06 25.4 0.5 2e-05 23.9 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain Kdo PF06293.9 KLO06721.1 - 0.013 14.5 0.0 0.025 13.6 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 KLO06721.1 - 0.016 14.5 0.3 0.067 12.5 0.1 2.0 2 0 0 2 2 2 0 RIO1 family DUF1943 PF09172.6 KLO06721.1 - 0.03 13.1 0.0 0.061 12.1 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1943) Pkinase PF00069.20 KLO06722.1 - 5e-08 32.4 0.0 1e-07 31.3 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.9 KLO06722.1 - 0.0012 17.9 0.1 0.0036 16.3 0.0 1.8 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_Tyr PF07714.12 KLO06722.1 - 0.035 13.1 0.0 0.059 12.4 0.0 1.2 1 0 0 1 1 1 0 Protein tyrosine kinase Gal-bind_lectin PF00337.17 KLO06722.1 - 0.079 12.2 0.0 0.15 11.4 0.0 1.3 1 0 0 1 1 1 0 Galactoside-binding lectin MFS_1 PF07690.11 KLO06723.1 - 2.1e-26 92.4 25.4 2.1e-26 92.4 17.6 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily Adaptin_N PF01602.15 KLO06725.1 - 2.3e-132 442.0 5.1 2.7e-132 441.7 3.5 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.2 KLO06725.1 - 6.1e-26 91.3 1.0 1.9e-23 83.2 0.1 2.9 2 0 0 2 2 2 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.1 KLO06725.1 - 3.7e-16 59.1 2.2 7.7e-09 35.7 0.1 4.2 2 2 2 4 4 4 3 HEAT repeats HEAT PF02985.17 KLO06725.1 - 5.6e-07 29.1 5.4 0.067 13.3 0.0 5.5 7 0 0 7 7 7 3 HEAT repeat Arm PF00514.18 KLO06725.1 - 0.00029 20.5 0.8 0.17 11.7 0.0 4.4 4 0 0 4 4 4 1 Armadillo/beta-catenin-like repeat CLASP_N PF12348.3 KLO06725.1 - 0.0012 18.2 0.0 0.43 9.9 0.0 2.7 2 0 0 2 2 2 2 CLASP N terminal Cnd3 PF12719.2 KLO06725.1 - 0.002 17.1 0.1 0.28 10.1 0.0 2.3 2 0 0 2 2 2 2 Nuclear condensing complex subunits, C-term domain HEAT_EZ PF13513.1 KLO06725.1 - 0.0068 16.8 3.0 3.2 8.3 0.0 5.3 5 1 1 6 6 6 1 HEAT-like repeat FANCI_S2 PF14676.1 KLO06725.1 - 0.24 11.3 2.4 32 4.3 0.1 3.7 3 1 0 3 3 3 0 FANCI solenoid 2 DUF4477 PF14780.1 KLO06726.1 - 6.8e-13 48.4 0.0 8.3e-13 48.1 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4477) TMEM187 PF15100.1 KLO06726.1 - 0.058 12.7 0.1 0.089 12.1 0.0 1.2 1 0 0 1 1 1 0 TMEM187 protein family Nup54 PF13874.1 KLO06726.1 - 0.11 12.1 0.1 6.1 6.5 0.0 2.3 2 0 0 2 2 2 0 Nucleoporin complex subunit 54 CHCH PF06747.8 KLO06727.1 - 1.7e-05 24.6 0.2 2.9e-05 23.8 0.2 1.4 1 1 0 1 1 1 1 CHCH domain Cmc1 PF08583.5 KLO06727.1 - 0.0012 18.6 0.7 0.0013 18.4 0.5 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like GCK PF07802.6 KLO06727.1 - 0.14 12.3 0.7 0.53 10.4 0.4 1.8 1 1 1 2 2 2 0 GCK domain UQ_con PF00179.21 KLO06728.1 - 2.7e-21 75.4 0.0 5.5e-21 74.4 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme zf-RanBP PF00641.13 KLO06728.1 - 0.045 12.8 0.3 0.045 12.8 0.2 2.0 2 0 0 2 2 2 0 Zn-finger in Ran binding protein and others Rubredoxin PF00301.15 KLO06728.1 - 0.41 10.5 2.7 0.45 10.4 0.0 2.4 2 1 0 2 2 2 0 Rubredoxin PRP21_like_P PF12230.3 KLO06730.1 - 9.9e-56 188.7 15.6 9.9e-56 188.7 10.8 2.3 2 0 0 2 2 2 1 Pre-mRNA splicing factor PRP21 like protein Surp PF01805.15 KLO06730.1 - 1.8e-26 91.5 1.5 9.9e-13 47.5 0.0 3.0 3 0 0 3 3 3 2 Surp module ubiquitin PF00240.18 KLO06730.1 - 9.5e-07 28.1 0.0 2.3e-06 26.9 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 KLO06730.1 - 0.0057 16.3 0.0 0.015 14.9 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF244 PF03112.9 KLO06730.1 - 0.94 9.0 4.2 0.19 11.2 0.1 1.8 2 0 0 2 2 2 0 Uncharacterized protein family (ORF7) DUF L31 PF09784.4 KLO06731.1 - 4.7e-40 135.8 0.1 5.3e-40 135.6 0.1 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L31 CMS1 PF14617.1 KLO06732.1 - 1e-67 227.8 0.0 1.2e-67 227.6 0.0 1.0 1 0 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit RNase_T PF00929.19 KLO06733.1 - 4.4e-13 49.8 0.0 1.1e-11 45.3 0.0 2.1 1 1 0 1 1 1 1 Exonuclease MoCF_biosynth PF00994.19 KLO06735.1 - 9.5e-34 115.8 0.0 2.5e-33 114.5 0.0 1.6 2 0 0 2 2 2 1 Probable molybdopterin binding domain DUF917 PF06032.7 KLO06736.1 - 6.5e-104 347.2 0.0 1.1e-103 346.5 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF917) Hydantoinase_A PF01968.13 KLO06736.1 - 2.2e-49 168.1 9.7 5.8e-48 163.4 3.8 2.4 2 0 0 2 2 2 2 Hydantoinase/oxoprolinase Hydant_A_N PF05378.8 KLO06736.1 - 2.8e-26 92.0 5.2 1.2e-24 86.7 0.0 2.9 3 1 0 3 3 3 2 Hydantoinase/oxoprolinase N-terminal region BcrAD_BadFG PF01869.15 KLO06736.1 - 1.4e-07 31.0 1.4 1.1e-05 24.9 0.3 2.6 2 1 0 2 2 2 1 BadF/BadG/BcrA/BcrD ATPase family IstB_IS21 PF01695.12 KLO06736.1 - 0.00021 20.7 0.0 0.00037 19.9 0.0 1.3 1 0 0 1 1 1 1 IstB-like ATP binding protein MutL PF13941.1 KLO06736.1 - 0.00078 17.8 1.8 0.18 10.1 0.0 2.3 2 0 0 2 2 2 2 MutL protein FtsA PF14450.1 KLO06736.1 - 0.00082 19.2 6.5 0.022 14.6 0.1 3.6 3 0 0 3 3 3 1 Cell division protein FtsA FGGY_N PF00370.16 KLO06736.1 - 0.01 15.1 0.4 0.019 14.2 0.3 1.4 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, N-terminal domain StbA PF06406.6 KLO06736.1 - 0.023 13.6 0.2 3.5 6.4 0.0 2.4 2 0 0 2 2 2 0 StbA protein Smg4_UPF3 PF03467.10 KLO06737.1 - 1.5e-31 109.7 0.0 1.5e-31 109.7 0.0 1.7 2 0 0 2 2 2 1 Smg-4/UPF3 family TFIIA PF03153.8 KLO06737.1 - 0.2 11.4 11.3 0.37 10.6 7.8 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF572 PF04502.8 KLO06737.1 - 9.1 5.3 13.3 17 4.5 9.2 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF572) MCM PF00493.18 KLO06738.1 - 2.6e-132 440.6 0.0 4e-132 440.0 0.0 1.2 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 KLO06738.1 - 1.3e-22 80.5 0.1 8e-22 77.9 0.0 2.3 2 1 0 2 2 2 1 MCM N-terminal domain AAA_5 PF07728.9 KLO06738.1 - 9.9e-08 31.8 0.0 2.6e-07 30.4 0.0 1.8 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.16 KLO06738.1 - 1.6e-07 30.6 0.0 5.9e-05 22.3 0.0 2.3 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_3 PF07726.6 KLO06738.1 - 0.00062 19.3 0.0 0.0065 16.0 0.0 2.3 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 KLO06738.1 - 0.00098 18.6 0.0 0.88 9.0 0.0 3.2 3 0 0 3 3 3 2 Sigma-54 interaction domain RPA_C PF08784.6 KLO06738.1 - 0.093 13.1 0.0 0.32 11.4 0.0 1.9 1 0 0 1 1 1 0 Replication protein A C terminal GPI-anchored PF10342.4 KLO06740.1 - 5.1e-07 30.0 1.1 5.1e-07 30.0 0.8 2.0 2 1 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family ORC3_N PF07034.6 KLO06741.1 - 4.7e-24 84.9 0.0 3.9e-23 81.9 0.0 2.0 1 1 0 1 1 1 1 Origin recognition complex (ORC) subunit 3 N-terminus DUF2052 PF09747.4 KLO06741.1 - 0.039 13.8 0.1 0.078 12.9 0.1 1.4 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) Aa_trans PF01490.13 KLO06742.1 - 4.1e-26 91.3 32.0 5.8e-26 90.9 22.2 1.3 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein UBACT PF02134.16 KLO06742.1 - 0.026 14.1 0.2 0.061 12.8 0.1 1.6 1 0 0 1 1 1 0 Repeat in ubiquitin-activating (UBA) protein SYF2 PF08231.7 KLO06744.1 - 4.2e-45 153.5 24.4 4.2e-45 153.5 16.9 2.8 2 2 0 2 2 2 1 SYF2 splicing factor Lactococcin PF04369.8 KLO06744.1 - 0.019 14.8 0.0 0.043 13.7 0.0 1.5 1 0 0 1 1 1 0 Lactococcin-like family Pyr_redox_2 PF07992.9 KLO06745.1 - 2.7e-30 105.7 0.0 8.5e-30 104.1 0.0 2.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 KLO06745.1 - 5.9e-13 49.0 0.0 1.9e-10 40.9 0.0 2.9 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 KLO06745.1 - 0.00022 21.3 0.1 0.0044 17.1 0.0 2.8 2 1 1 4 4 4 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 KLO06745.1 - 0.16 10.8 0.0 0.33 9.7 0.0 1.5 1 0 0 1 1 1 0 FAD binding domain Aa_trans PF01490.13 KLO06746.1 - 6.8e-25 87.3 33.4 9.4e-25 86.9 23.1 1.3 1 1 0 1 1 1 1 Transmembrane amino acid transporter protein DLH PF01738.13 KLO06747.1 - 4.6e-22 78.3 0.0 5.6e-22 78.0 0.0 1.0 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 KLO06747.1 - 9.8e-07 28.6 0.0 1.5e-06 28.0 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KLO06747.1 - 0.00025 21.0 0.0 0.59 9.9 0.0 2.1 1 1 1 2 2 2 2 Alpha/beta hydrolase family DLH PF01738.13 KLO06748.1 - 1.1e-23 83.7 0.0 1.3e-23 83.4 0.0 1.0 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 KLO06748.1 - 7.8e-09 35.4 0.0 1.1e-08 34.9 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KLO06748.1 - 0.00028 20.8 0.0 0.33 10.7 0.0 2.1 1 1 1 2 2 2 2 Alpha/beta hydrolase family DLH PF01738.13 KLO06749.1 - 2.4e-23 82.5 0.0 2.9e-23 82.3 0.0 1.0 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 KLO06749.1 - 4.3e-09 36.2 0.0 6.5e-09 35.6 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KLO06749.1 - 0.00035 20.5 0.0 0.11 12.3 0.0 2.1 1 1 1 2 2 2 2 Alpha/beta hydrolase family SH3_2 PF07653.12 KLO06752.1 - 0.00064 19.1 0.0 0.00088 18.7 0.0 1.2 1 0 0 1 1 1 1 Variant SH3 domain RabGAP-TBC PF00566.13 KLO06753.1 - 3.3e-34 118.2 0.0 4.4e-34 117.8 0.0 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain F-box-like PF12937.2 KLO06754.1 - 0.0074 15.9 0.0 0.026 14.2 0.0 2.0 2 0 0 2 2 2 1 F-box-like Pkinase PF00069.20 KLO06755.1 - 6e-72 241.9 0.0 3.2e-69 232.9 0.0 2.0 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 KLO06755.1 - 1.6e-35 122.4 0.0 2.6e-32 111.9 0.0 2.0 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 KLO06755.1 - 0.00039 19.4 0.0 0.00059 18.8 0.0 1.3 1 0 0 1 1 1 1 Kinase-like YrbL-PhoP_reg PF10707.4 KLO06755.1 - 0.0025 17.1 0.0 0.0044 16.3 0.0 1.3 1 0 0 1 1 1 1 PhoP regulatory network protein YrbL Kdo PF06293.9 KLO06755.1 - 0.011 14.8 0.0 0.019 14.0 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family SR-25 PF10500.4 KLO06755.1 - 0.015 14.7 0.7 0.023 14.1 0.5 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF4530 PF15039.1 KLO06756.1 - 0.15 12.0 0.3 0.32 10.9 0.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4530) PNP_UDP_1 PF01048.15 KLO06757.1 - 2.8e-22 78.8 0.0 4.6e-22 78.1 0.0 1.3 1 0 0 1 1 1 1 Phosphorylase superfamily LRR_4 PF12799.2 KLO06760.1 - 0.028 14.0 0.1 0.27 10.9 0.0 2.7 3 0 0 3 3 3 0 Leucine Rich repeats (2 copies) RIX1 PF08167.7 KLO06760.1 - 0.047 13.3 0.0 0.12 12.0 0.0 1.6 1 0 0 1 1 1 0 rRNA processing/ribosome biogenesis Fasciclin PF02469.17 KLO06763.1 - 5.3e-26 91.1 1.7 3.1e-12 46.6 0.0 4.1 4 0 0 4 4 4 4 Fasciclin domain DUF1049 PF06305.6 KLO06764.1 - 0.097 12.1 0.0 0.13 11.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1049) Glyco_hydro_16 PF00722.16 KLO06765.1 - 9.1e-21 73.9 0.0 1.9e-20 72.9 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 NACHT PF05729.7 KLO06766.1 - 1.1e-10 41.4 0.1 1.7e-10 40.7 0.1 1.3 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 KLO06766.1 - 1.8e-06 28.0 0.2 5.6e-06 26.4 0.2 1.7 1 1 0 1 1 1 1 AAA ATPase domain NB-ARC PF00931.17 KLO06766.1 - 3.9e-06 25.9 0.0 5.6e-06 25.4 0.0 1.2 1 0 0 1 1 1 1 NB-ARC domain AAA_22 PF13401.1 KLO06766.1 - 0.00021 21.4 0.0 0.00057 20.0 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA PF00004.24 KLO06766.1 - 0.0032 17.6 0.0 0.013 15.6 0.0 1.9 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) KAP_NTPase PF07693.9 KLO06766.1 - 0.0061 15.5 0.0 0.0083 15.1 0.0 1.2 1 0 0 1 1 1 1 KAP family P-loop domain APS_kinase PF01583.15 KLO06766.1 - 0.0082 15.8 0.7 0.043 13.4 0.2 2.1 1 1 1 2 2 2 1 Adenylylsulphate kinase AAA_30 PF13604.1 KLO06766.1 - 0.034 13.7 0.1 0.083 12.4 0.0 1.7 1 1 0 1 1 1 0 AAA domain HemN_C PF06969.11 KLO06766.1 - 0.092 12.8 0.0 19 5.3 0.0 2.5 2 0 0 2 2 2 0 HemN C-terminal domain AAA_14 PF13173.1 KLO06766.1 - 0.097 12.5 0.0 4.6 7.1 0.0 2.3 1 1 0 2 2 2 0 AAA domain Peptidase_S10 PF00450.17 KLO06769.1 - 1e-79 268.6 0.1 1.4e-79 268.2 0.1 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase AA_permease PF00324.16 KLO06770.1 - 1.4e-107 359.9 34.9 1.7e-107 359.7 24.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 KLO06770.1 - 3.3e-31 108.2 41.8 4.1e-31 107.9 29.0 1.1 1 0 0 1 1 1 1 Amino acid permease DUF4051 PF13260.1 KLO06770.1 - 0.076 12.3 0.0 0.26 10.6 0.0 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4051) HEAT PF02985.17 KLO06772.1 - 7.2e-13 47.4 5.2 4.6e-05 23.1 0.0 6.8 7 0 0 7 7 7 3 HEAT repeat HEAT_2 PF13646.1 KLO06772.1 - 1.6e-11 44.3 4.9 5.9e-06 26.4 0.0 6.4 6 2 1 7 7 7 3 HEAT repeats HEAT_EZ PF13513.1 KLO06772.1 - 3.8e-10 39.9 17.2 0.019 15.4 0.1 9.0 8 1 1 9 9 9 3 HEAT-like repeat Vac14_Fab1_bd PF12755.2 KLO06772.1 - 4.3e-09 36.6 0.0 0.0037 17.6 0.0 4.7 4 1 1 5 5 5 2 Vacuolar 14 Fab1-binding region RIX1 PF08167.7 KLO06772.1 - 7.9e-08 32.1 0.7 0.00058 19.5 0.0 4.7 5 0 0 5 5 5 1 rRNA processing/ribosome biogenesis DUF4042 PF13251.1 KLO06772.1 - 9e-05 22.0 0.0 1.5 8.2 0.0 3.5 3 0 0 3 3 3 2 Domain of unknown function (DUF4042) MMS19_C PF12460.3 KLO06772.1 - 0.0019 17.0 0.0 2.1 6.9 0.0 4.1 3 1 1 4 4 4 1 RNAPII transcription regulator C-terminal Adaptin_N PF01602.15 KLO06772.1 - 0.0027 16.0 0.0 0.57 8.4 0.0 3.1 2 1 0 2 2 2 1 Adaptin N terminal region CLASP_N PF12348.3 KLO06772.1 - 0.04 13.2 0.1 6.3 6.0 0.0 3.5 5 0 0 5 5 5 0 CLASP N terminal TPR_14 PF13428.1 KLO06772.1 - 0.057 14.0 1.0 0.73 10.6 0.0 3.4 4 0 0 4 4 4 0 Tetratricopeptide repeat Shisa PF13908.1 KLO06773.1 - 0.00021 21.5 0.5 0.00036 20.7 0.3 1.3 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator FAD_binding_3 PF01494.14 KLO06774.1 - 1.3e-25 90.1 0.1 3.6e-25 88.7 0.1 1.7 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 KLO06774.1 - 4.9e-08 32.2 1.9 1.8e-05 23.8 1.3 2.4 1 1 0 2 2 2 2 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 KLO06774.1 - 6.8e-08 31.8 0.2 1e-06 27.9 0.1 2.1 1 1 0 1 1 1 1 Lycopene cyclase protein FAD_binding_2 PF00890.19 KLO06774.1 - 6.9e-06 25.1 1.0 6.9e-06 25.1 0.7 2.0 2 0 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.1 KLO06774.1 - 9.4e-06 25.5 0.5 3.7e-05 23.6 0.3 2.1 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.9 KLO06774.1 - 2e-05 23.2 0.1 7.3e-05 21.4 0.1 1.8 1 1 0 1 1 1 1 HI0933-like protein Pyr_redox PF00070.22 KLO06774.1 - 2.5e-05 24.5 0.0 0.0023 18.3 0.1 2.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 KLO06774.1 - 2.7e-05 24.1 0.1 6e-05 23.0 0.1 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 KLO06774.1 - 0.00026 19.9 0.1 0.00061 18.7 0.2 1.5 2 0 0 2 2 2 1 Glucose inhibited division protein A Trp_halogenase PF04820.9 KLO06774.1 - 0.00043 19.0 0.4 0.34 9.4 0.3 2.5 3 0 0 3 3 3 2 Tryptophan halogenase Amino_oxidase PF01593.19 KLO06774.1 - 0.00055 19.1 1.7 0.49 9.4 0.7 2.3 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase AlaDh_PNT_C PF01262.16 KLO06774.1 - 0.0032 17.0 0.1 0.0061 16.1 0.0 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox_3 PF13738.1 KLO06774.1 - 0.0051 16.9 0.0 0.016 15.2 0.0 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 KLO06774.1 - 0.015 14.3 0.9 0.044 12.8 0.6 1.9 1 1 0 1 1 1 0 FAD dependent oxidoreductase 3HCDH_N PF02737.13 KLO06774.1 - 0.017 14.7 0.1 0.031 13.9 0.1 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.9 KLO06774.1 - 0.019 14.3 0.0 0.03 13.7 0.0 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Rossmann-like PF10727.4 KLO06774.1 - 0.047 13.4 0.8 0.11 12.2 0.1 2.0 2 0 0 2 2 2 0 Rossmann-like domain IlvN PF07991.7 KLO06774.1 - 0.048 13.0 0.1 1.8 7.8 0.0 2.3 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, catalytic domain Thi4 PF01946.12 KLO06774.1 - 0.059 12.4 0.1 0.1 11.6 0.0 1.3 1 0 0 1 1 1 0 Thi4 family zf-MYND PF01753.13 KLO06775.1 - 3.4e-07 30.0 17.7 8.2e-07 28.8 12.2 1.7 1 0 0 1 1 1 1 MYND finger DUF4224 PF13986.1 KLO06775.1 - 0.038 13.5 0.1 0.14 11.6 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4224) Ecl1 PF12855.2 KLO06775.1 - 0.19 11.0 4.8 0.4 9.9 3.3 1.5 1 0 0 1 1 1 0 Life-span regulatory factor Peptidase_S24 PF00717.18 KLO06776.1 - 5.9e-09 35.4 0.0 1.1e-08 34.5 0.0 1.4 1 0 0 1 1 1 1 Peptidase S24-like Peptidase_S26 PF10502.4 KLO06776.1 - 2.5e-07 30.3 0.0 0.00012 21.5 0.0 2.6 1 1 1 2 2 2 2 Signal peptidase, peptidase S26 TPR_11 PF13414.1 KLO06777.1 - 2.4e-10 39.9 1.3 0.00057 19.4 0.0 3.0 3 1 0 3 3 3 2 TPR repeat TPR_2 PF07719.12 KLO06777.1 - 1.2e-06 28.0 0.1 0.13 12.1 0.0 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.23 KLO06777.1 - 2.6e-06 26.7 0.2 0.065 12.8 0.0 3.3 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.1 KLO06777.1 - 0.00055 20.3 0.2 1.6 9.5 0.0 2.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.1 KLO06777.1 - 0.00056 20.5 0.2 1.5 9.5 0.1 3.0 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.1 KLO06777.1 - 0.0031 17.1 0.0 0.24 11.2 0.0 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.1 KLO06777.1 - 0.0084 16.4 0.2 0.57 10.5 0.1 2.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.1 KLO06777.1 - 0.023 14.6 0.1 8.3 6.4 0.0 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF465 PF04325.8 KLO06778.1 - 0.012 15.2 0.4 0.047 13.4 0.3 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF465) Response_reg PF00072.19 KLO06778.1 - 0.069 13.1 0.2 0.9 9.5 0.1 2.6 2 0 0 2 2 2 0 Response regulator receiver domain CutC PF03932.9 KLO06779.1 - 1.9e-48 164.4 0.1 2.2e-48 164.1 0.1 1.1 1 0 0 1 1 1 1 CutC family SEN1_N PF12726.2 KLO06779.1 - 0.18 9.8 0.0 0.24 9.3 0.0 1.1 1 0 0 1 1 1 0 SEN1 N terminal Choline_kinase PF01633.15 KLO06780.1 - 0.17 11.4 0.0 0.31 10.5 0.0 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase SUR7 PF06687.7 KLO06783.1 - 8.8e-19 67.9 13.7 1.3e-18 67.3 9.5 1.2 1 0 0 1 1 1 1 SUR7/PalI family LRR_4 PF12799.2 KLO06784.1 - 0.12 12.0 0.1 4 7.1 0.0 2.8 3 0 0 3 3 3 0 Leucine Rich repeats (2 copies) F-box-like PF12937.2 KLO06785.1 - 1.2e-07 31.3 2.4 1.2e-07 31.3 0.2 2.2 2 0 0 2 2 2 1 F-box-like Poxvirus PF06227.7 KLO06785.1 - 0.027 14.0 0.0 0.047 13.2 0.0 1.3 1 0 0 1 1 1 0 dsDNA Poxvirus LRR_4 PF12799.2 KLO06785.1 - 0.12 12.0 1.1 6 6.6 0.1 3.5 2 1 1 3 3 3 0 Leucine Rich repeats (2 copies) F-box-like PF12937.2 KLO06786.1 - 0.00039 20.0 0.1 0.00039 20.0 0.1 2.3 2 0 0 2 2 2 1 F-box-like DUF3152 PF11350.3 KLO06786.1 - 0.023 14.2 0.1 0.037 13.5 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3152) Condensation PF00668.15 KLO06787.1 - 0.16 10.8 0.0 8.2 5.1 0.0 2.5 2 0 0 2 2 2 0 Condensation domain O-FucT PF10250.4 KLO06788.1 - 1.1e-07 31.3 0.0 6.9e-05 22.1 0.0 2.6 3 0 0 3 3 3 2 GDP-fucose protein O-fucosyltransferase Glyco_transf_11 PF01531.11 KLO06788.1 - 0.044 12.7 0.0 0.081 11.9 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferase family 11 TPT PF03151.11 KLO06789.1 - 1.9e-06 27.6 10.9 1.9e-06 27.6 7.6 3.5 3 1 0 3 3 3 1 Triose-phosphate Transporter family COPI_assoc PF08507.5 KLO06789.1 - 0.00095 18.8 0.0 0.00095 18.8 0.0 3.0 3 0 0 3 3 3 1 COPI associated protein EamA PF00892.15 KLO06789.1 - 0.011 15.7 5.7 0.011 15.7 3.9 3.3 1 1 2 3 3 3 0 EamA-like transporter family UbiA PF01040.13 KLO06791.1 - 3.3e-24 85.5 20.8 4.2e-24 85.1 14.4 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family DUF1761 PF08570.5 KLO06791.1 - 0.23 11.4 8.4 0.15 12.0 2.4 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF1761) Methyltransf_2 PF00891.13 KLO06792.1 - 2e-06 27.2 0.0 2.9e-06 26.6 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_12 PF08242.7 KLO06792.1 - 0.035 14.5 0.0 0.87 10.1 0.0 2.5 2 0 0 2 2 2 0 Methyltransferase domain Dimerisation PF08100.6 KLO06792.1 - 0.08 12.7 0.3 0.2 11.5 0.0 1.8 2 0 0 2 2 2 0 Dimerisation domain NAD_binding_4 PF07993.7 KLO06793.1 - 4.5e-36 124.0 0.0 7.3e-36 123.3 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.23 KLO06793.1 - 7.5e-31 106.9 0.0 1e-30 106.4 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme Epimerase PF01370.16 KLO06793.1 - 6.7e-08 32.2 0.0 1.2e-07 31.3 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.20 KLO06793.1 - 0.00022 21.4 0.0 0.00047 20.3 0.0 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site adh_short PF00106.20 KLO06793.1 - 0.044 13.6 0.2 0.16 11.9 0.1 2.0 1 1 0 1 1 1 0 short chain dehydrogenase 3Beta_HSD PF01073.14 KLO06793.1 - 0.18 10.4 0.0 0.38 9.4 0.0 1.4 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 KLO06794.1 - 1e-33 116.2 0.0 1.5e-33 115.7 0.0 1.2 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.23 KLO06794.1 - 1.7e-27 95.9 0.0 3.2e-27 95.0 0.0 1.4 1 1 0 1 1 1 1 AMP-binding enzyme Epimerase PF01370.16 KLO06794.1 - 5.4e-11 42.3 0.0 1.1e-10 41.3 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.20 KLO06794.1 - 5.6e-05 23.3 0.0 0.00012 22.2 0.0 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site adh_short PF00106.20 KLO06794.1 - 0.00017 21.5 0.2 0.00052 19.9 0.1 1.8 1 1 0 1 1 1 1 short chain dehydrogenase 3Beta_HSD PF01073.14 KLO06794.1 - 0.038 12.6 0.0 0.17 10.5 0.0 1.9 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family KR PF08659.5 KLO06794.1 - 0.052 13.2 0.0 0.093 12.3 0.0 1.4 1 0 0 1 1 1 0 KR domain p450 PF00067.17 KLO06796.1 - 4.9e-74 249.5 0.0 5.5e-74 249.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Abhydrolase_3 PF07859.8 KLO06798.1 - 8.7e-12 45.0 0.0 2.5e-11 43.5 0.0 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KLO06798.1 - 1.2e-09 38.0 0.0 2e-09 37.3 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family COesterase PF00135.23 KLO06798.1 - 2.5e-09 36.3 0.4 1.3e-08 34.0 0.2 1.8 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_6 PF12697.2 KLO06798.1 - 1.8e-08 34.5 0.2 5.6e-08 32.9 0.2 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 KLO06798.1 - 0.0028 16.9 0.0 0.012 14.8 0.0 2.1 1 1 0 1 1 1 1 Prolyl oligopeptidase family DUF2424 PF10340.4 KLO06798.1 - 0.0082 14.8 0.0 0.011 14.3 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2424) Abhydrolase_1 PF00561.15 KLO06798.1 - 0.013 15.1 0.0 0.014 15.0 0.0 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold Lipase_3 PF01764.20 KLO06798.1 - 0.028 14.0 0.0 0.045 13.3 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) PGAP1 PF07819.8 KLO06798.1 - 0.048 13.2 0.0 0.07 12.7 0.0 1.2 1 0 0 1 1 1 0 PGAP1-like protein PAF-AH_p_II PF03403.8 KLO06798.1 - 0.12 10.5 0.4 0.46 8.7 0.0 1.9 1 1 1 2 2 2 0 Platelet-activating factor acetylhydrolase, isoform II FAD_binding_3 PF01494.14 KLO06801.1 - 5.1e-83 279.0 0.0 7.6e-83 278.4 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.7 KLO06801.1 - 2.1e-25 89.2 0.0 3.5e-25 88.5 0.0 1.3 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain HI0933_like PF03486.9 KLO06801.1 - 7.9e-06 24.5 0.8 1.2e-05 24.0 0.5 1.2 1 0 0 1 1 1 1 HI0933-like protein FAD_binding_2 PF00890.19 KLO06801.1 - 2.1e-05 23.5 1.7 3.8e-05 22.7 1.2 1.4 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 KLO06801.1 - 0.00041 20.2 0.6 0.0012 18.7 0.4 1.8 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 KLO06801.1 - 0.0011 19.3 0.1 0.017 15.5 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 KLO06801.1 - 0.0012 18.0 0.8 0.0022 17.1 0.1 1.7 2 0 0 2 2 2 1 Thi4 family NAD_binding_8 PF13450.1 KLO06801.1 - 0.0014 18.6 0.1 0.0033 17.3 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain AlaDh_PNT_C PF01262.16 KLO06801.1 - 0.0018 17.8 0.2 0.0031 17.0 0.1 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain DAO PF01266.19 KLO06801.1 - 0.0074 15.2 0.2 0.012 14.5 0.1 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_oxidored PF12831.2 KLO06801.1 - 0.0095 15.0 0.1 0.013 14.5 0.1 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase GIDA PF01134.17 KLO06801.1 - 0.0098 14.7 0.9 0.02 13.7 0.6 1.5 1 0 0 1 1 1 1 Glucose inhibited division protein A 3HCDH_N PF02737.13 KLO06801.1 - 0.011 15.3 0.2 0.019 14.5 0.1 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Lycopene_cycl PF05834.7 KLO06801.1 - 0.012 14.5 0.6 0.019 13.8 0.4 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein UDPG_MGDP_dh_N PF03721.9 KLO06801.1 - 0.025 13.9 0.1 0.045 13.1 0.0 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NAD_binding_9 PF13454.1 KLO06801.1 - 0.041 13.6 0.1 0.08 12.7 0.1 1.5 1 0 0 1 1 1 0 FAD-NAD(P)-binding Pyr_redox_3 PF13738.1 KLO06801.1 - 0.043 13.8 0.1 0.082 12.9 0.1 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.1 KLO06801.1 - 0.081 13.1 0.0 0.17 12.1 0.0 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding YbbR PF07949.7 KLO06801.1 - 0.1 12.7 0.1 0.28 11.3 0.1 1.7 1 0 0 1 1 1 0 YbbR-like protein F-box-like PF12937.2 KLO06803.1 - 4.7e-05 23.0 0.0 0.00013 21.6 0.0 1.8 1 0 0 1 1 1 1 F-box-like F-box-like PF12937.2 KLO06804.1 - 0.00025 20.7 0.1 0.00071 19.2 0.0 1.8 1 0 0 1 1 1 1 F-box-like Tet_JBP PF12851.2 KLO06807.1 - 1.3e-11 44.1 0.0 1.5e-11 43.9 0.0 1.1 1 0 0 1 1 1 1 Oxygenase domain of the 2OGFeDO superfamily BTB PF00651.26 KLO06811.1 - 0.0006 19.7 0.2 0.0012 18.7 0.2 1.6 1 0 0 1 1 1 1 BTB/POZ domain BTB PF00651.26 KLO06812.1 - 9.4e-07 28.8 0.1 4.1e-06 26.7 0.1 2.1 1 1 0 1 1 1 1 BTB/POZ domain BTB PF00651.26 KLO06813.1 - 1.5e-06 28.1 0.0 4e-06 26.7 0.0 1.7 1 1 0 1 1 1 1 BTB/POZ domain BTB PF00651.26 KLO06814.1 - 9.5e-06 25.5 0.0 1.9e-05 24.6 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain Red1 PF07964.6 KLO06814.1 - 0.13 10.3 0.0 0.3 9.1 0.0 1.5 2 0 0 2 2 2 0 Rec10 / Red1 MFS_1 PF07690.11 KLO06816.1 - 3e-39 134.7 40.0 4.1e-39 134.2 24.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KLO06816.1 - 1.1e-11 44.0 21.1 4e-11 42.1 14.6 1.8 1 1 0 1 1 1 1 Sugar (and other) transporter TRI12 PF06609.8 KLO06816.1 - 5.4e-11 41.4 2.0 9.5e-11 40.5 1.4 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) BTB PF00651.26 KLO06817.1 - 0.00024 21.0 0.0 0.00059 19.8 0.0 1.6 1 0 0 1 1 1 1 BTB/POZ domain BTB PF00651.26 KLO06818.1 - 0.00013 21.9 0.1 0.00043 20.2 0.1 1.8 1 1 0 1 1 1 1 BTB/POZ domain BTB PF00651.26 KLO06820.1 - 0.00057 19.8 0.3 0.0018 18.2 0.2 1.9 1 1 0 1 1 1 1 BTB/POZ domain BTB PF00651.26 KLO06821.1 - 3.4e-05 23.7 0.0 9.1e-05 22.4 0.0 1.7 1 1 0 1 1 1 1 BTB/POZ domain BTB PF00651.26 KLO06823.1 - 1.2e-05 25.2 0.0 5.9e-05 23.0 0.0 2.1 1 1 0 1 1 1 1 BTB/POZ domain BTB PF00651.26 KLO06824.1 - 0.0001 22.2 0.0 0.00039 20.3 0.0 1.9 1 1 0 1 1 1 1 BTB/POZ domain BTB PF00651.26 KLO06825.1 - 0.00087 19.2 0.0 0.0029 17.5 0.0 2.0 1 1 0 1 1 1 1 BTB/POZ domain DUF2645 PF10840.3 KLO06826.1 - 0.069 13.3 0.1 0.12 12.5 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2645) p450 PF00067.17 KLO06827.1 - 3.9e-65 220.1 0.0 4.9e-65 219.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Suf PF05843.9 KLO06827.1 - 0.15 11.7 0.0 0.22 11.2 0.0 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Complex1_LYR PF05347.10 KLO06829.1 - 4.9e-10 39.0 0.0 9.3e-10 38.1 0.0 1.5 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 KLO06829.1 - 7.6e-09 35.6 0.0 1.5e-08 34.6 0.0 1.4 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR_2 PF13233.1 KLO06829.1 - 3.6e-06 27.3 0.0 5.2e-06 26.8 0.0 1.3 1 0 0 1 1 1 1 Complex1_LYR-like Cyanate_lyase PF02560.9 KLO06830.1 - 1.3e-33 114.3 0.0 1.8e-33 113.8 0.0 1.3 1 0 0 1 1 1 1 Cyanate lyase C-terminal domain HTH_31 PF13560.1 KLO06830.1 - 0.00036 20.6 0.0 0.00056 20.0 0.0 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_19 PF12844.2 KLO06830.1 - 0.086 12.9 0.0 0.14 12.2 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain KorB PF08535.5 KLO06830.1 - 0.11 12.7 0.0 0.23 11.6 0.0 1.6 2 0 0 2 2 2 0 KorB domain Sigma70_r4_2 PF08281.7 KLO06830.1 - 0.13 11.7 0.0 6.1 6.3 0.0 2.4 2 0 0 2 2 2 0 Sigma-70, region 4 HTH_3 PF01381.17 KLO06830.1 - 0.16 11.8 0.0 0.24 11.2 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix zf-C2H2_4 PF13894.1 KLO06831.1 - 0.018 15.3 7.4 1.2 9.6 0.1 3.2 4 0 0 4 4 4 0 C2H2-type zinc finger zf-C2H2 PF00096.21 KLO06831.1 - 0.027 14.8 2.4 5.1 7.6 0.1 2.8 2 0 0 2 2 2 0 Zinc finger, C2H2 type CK_II_beta PF01214.13 KLO06831.1 - 0.17 11.3 0.2 0.38 10.2 0.1 1.5 1 0 0 1 1 1 0 Casein kinase II regulatory subunit PRTase_3 PF15610.1 KLO06831.1 - 0.19 10.6 0.0 0.28 10.0 0.0 1.2 1 0 0 1 1 1 0 PRTase ComF-like DUF3014 PF11219.3 KLO06832.1 - 0.023 14.5 0.0 0.034 14.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3014) Nucleoporin_FG PF13634.1 KLO06833.1 - 0.0001 22.4 21.8 0.0001 22.4 15.1 1.9 2 0 0 2 2 2 1 Nucleoporin FG repeat region Glyco_hydro_61 PF03443.9 KLO06834.1 - 7.4e-46 156.7 0.0 8.7e-46 156.4 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Ni_hydr_CYTB PF01292.15 KLO06835.1 - 0.035 13.4 0.0 0.045 13.1 0.0 1.2 1 0 0 1 1 1 0 Prokaryotic cytochrome b561 DUF1191 PF06697.7 KLO06835.1 - 0.047 12.4 0.0 0.055 12.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1191) Herpes_gE PF02480.11 KLO06835.1 - 0.052 11.8 0.0 0.057 11.6 0.0 1.2 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E Syndecan PF01034.15 KLO06835.1 - 0.07 12.7 0.0 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 Syndecan domain TMEM154 PF15102.1 KLO06836.1 - 0.017 14.8 0.8 0.047 13.3 0.6 1.7 1 1 0 1 1 1 0 TMEM154 protein family DUF2768 PF10966.3 KLO06836.1 - 0.077 13.1 0.2 0.22 11.6 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2768) DUF2615 PF11027.3 KLO06836.1 - 0.087 12.7 0.0 0.24 11.3 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2615) DUF202 PF02656.10 KLO06836.1 - 0.15 12.2 4.2 0.55 10.4 2.9 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF202) WGG PF10273.4 KLO06837.1 - 1.9e-27 95.1 0.0 3.7e-27 94.2 0.0 1.5 1 0 0 1 1 1 1 Pre-rRNA-processing protein TSR2 DUF669 PF05037.8 KLO06837.1 - 0.015 15.1 0.1 0.021 14.6 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF669) RRP7 PF12923.2 KLO06837.1 - 0.039 13.9 1.4 0.089 12.8 0.9 1.8 1 1 0 1 1 1 0 Ribosomal RNA-processing protein 7 (RRP7) Cytomega_TRL10 PF06084.6 KLO06838.1 - 0.021 14.6 0.1 0.028 14.2 0.1 1.2 1 0 0 1 1 1 0 Cytomegalovirus TRL10 protein DUF2990 PF11693.3 KLO06838.1 - 0.11 12.3 0.8 2.2 8.2 1.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2990) Herpes_gE PF02480.11 KLO06839.1 - 0.038 12.2 0.0 0.048 11.9 0.0 1.2 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E Alpha_GJ PF03229.8 KLO06839.1 - 0.062 13.6 0.0 0.28 11.5 0.0 1.9 2 0 0 2 2 2 0 Alphavirus glycoprotein J DUF4112 PF13430.1 KLO06839.1 - 0.079 12.8 0.0 0.23 11.3 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4112) DUF2541 PF10807.3 KLO06840.1 - 0.003 17.3 0.5 0.0053 16.5 0.3 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2541) Spore_YpjB PF09577.5 KLO06840.1 - 0.13 11.7 0.0 0.23 11.0 0.0 1.3 1 0 0 1 1 1 0 Sporulation protein YpjB (SpoYpjB) DUF4448 PF14610.1 KLO06841.1 - 0.0045 16.4 0.2 0.014 14.8 0.0 2.1 2 1 0 2 2 2 1 Protein of unknown function (DUF4448) SKG6 PF08693.5 KLO06841.1 - 0.013 14.8 1.9 0.032 13.5 1.3 1.6 1 0 0 1 1 1 0 Transmembrane alpha-helix domain DAP10 PF07213.6 KLO06841.1 - 0.071 12.8 0.1 0.14 11.9 0.1 1.4 1 0 0 1 1 1 0 DAP10 membrane protein Rifin_STEVOR PF02009.11 KLO06841.1 - 0.11 12.0 0.0 0.18 11.4 0.0 1.2 1 0 0 1 1 1 0 Rifin/stevor family VPEP PF07589.6 KLO06841.1 - 5.3 7.0 7.2 11 6.0 5.0 1.6 1 0 0 1 1 1 0 PEP-CTERM motif Cellulase PF00150.13 KLO06842.1 - 5.3e-28 98.0 8.9 7.5e-28 97.5 6.1 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) CBM_1 PF00734.13 KLO06842.1 - 1.5e-12 46.9 10.9 4.3e-12 45.4 7.6 1.9 1 0 0 1 1 1 1 Fungal cellulose binding domain Cellulase-like PF12876.2 KLO06842.1 - 7.8e-08 32.6 0.0 2.6e-07 31.0 0.0 1.9 2 0 0 2 2 2 1 Sugar-binding cellulase-like Glyco_hydro_2_C PF02836.12 KLO06842.1 - 0.0014 17.5 0.1 0.0046 15.9 0.1 1.7 1 1 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Glyco_hydro_42 PF02449.10 KLO06842.1 - 0.0017 17.5 0.0 0.0037 16.4 0.0 1.6 1 1 0 1 1 1 1 Beta-galactosidase Glyco_hydro_10 PF00331.15 KLO06842.1 - 0.0028 16.7 0.2 0.0056 15.7 0.1 1.5 1 1 0 1 1 1 1 Glycosyl hydrolase family 10 SNARE_assoc PF09335.6 KLO06843.1 - 1.9e-16 60.4 7.2 1.9e-16 60.4 5.0 2.7 3 0 0 3 3 3 1 SNARE associated Golgi protein DUF4149 PF13664.1 KLO06843.1 - 0.046 13.7 7.0 2.5 8.1 0.0 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF4149) OSTbeta PF15048.1 KLO06843.1 - 0.06 13.4 0.0 0.14 12.2 0.0 1.5 1 0 0 1 1 1 0 Organic solute transporter subunit beta protein Yip1 PF04893.12 KLO06843.1 - 0.79 9.2 19.6 0.064 12.7 7.4 2.5 2 1 0 2 2 2 0 Yip1 domain DUF1349 PF07081.6 KLO06846.1 - 1.2e-26 93.2 0.1 1.5e-26 92.8 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1349) CRCB PF02537.10 KLO06848.1 - 0.22 11.4 0.3 0.22 11.4 0.2 2.0 1 1 1 2 2 2 0 CrcB-like protein Zip PF02535.17 KLO06849.1 - 0.032 13.2 2.6 0.053 12.5 0.4 2.0 2 0 0 2 2 2 0 ZIP Zinc transporter DUF2371 PF10177.4 KLO06849.1 - 0.23 11.3 0.9 0.84 9.5 0.0 2.3 2 1 1 3 3 3 0 Uncharacterised conserved protein (DUF2371) Ctr PF04145.10 KLO06849.1 - 0.57 10.2 4.7 8.3 6.4 0.1 3.2 2 1 1 3 3 3 0 Ctr copper transporter family DUF1183 PF06682.7 KLO06849.1 - 2.5 7.6 10.2 8.7 5.8 7.1 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1183) Shisa PF13908.1 KLO06849.1 - 3.6 7.7 10.3 0.15 12.2 0.2 2.8 1 1 1 2 2 2 0 Wnt and FGF inhibitory regulator DUF202 PF02656.10 KLO06849.1 - 8.9 6.6 9.9 10 6.4 1.9 3.1 2 1 0 2 2 2 0 Domain of unknown function (DUF202) DUF4536 PF15055.1 KLO06850.1 - 0.00033 20.6 2.5 0.00033 20.6 0.7 1.8 2 1 0 2 2 2 1 Domain of unknown function (DUF4536) DUF998 PF06197.8 KLO06850.1 - 0.04 13.2 0.4 0.046 13.0 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF998) Plasmid_stab_B PF10784.4 KLO06850.1 - 0.12 11.9 0.0 0.2 11.3 0.0 1.3 1 0 0 1 1 1 0 Plasmid stability protein Prok-RING_4 PF14447.1 KLO06851.1 - 0.072 12.6 0.3 0.093 12.2 0.2 1.2 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 WD40 PF00400.27 KLO06852.1 - 3e-175 562.6 41.0 9.1e-12 44.3 0.0 14.6 14 0 0 14 14 14 14 WD domain, G-beta repeat eIF2A PF08662.6 KLO06852.1 - 5.6e-20 71.8 0.0 0.0025 17.5 0.0 6.3 1 1 5 8 8 8 5 Eukaryotic translation initiation factor eIF2A PD40 PF07676.7 KLO06852.1 - 3.5e-13 48.8 0.5 4.3 7.0 0.0 11.3 14 0 0 14 14 14 1 WD40-like Beta Propeller Repeat Nup160 PF11715.3 KLO06852.1 - 1.5e-12 46.5 18.7 0.31 9.1 0.1 11.9 1 1 9 12 12 12 4 Nucleoporin Nup120/160 NACHT PF05729.7 KLO06852.1 - 1.7e-06 27.7 0.0 4.7e-06 26.3 0.0 1.7 2 0 0 2 2 2 1 NACHT domain Peptidase_S9_N PF02897.10 KLO06852.1 - 1.9e-05 23.4 0.3 3.1 6.2 0.0 6.1 3 2 4 7 7 7 1 Prolyl oligopeptidase, N-terminal beta-propeller domain SdiA-regulated PF06977.6 KLO06852.1 - 2.3e-05 23.4 0.0 2.1 7.2 0.0 4.7 2 2 4 6 6 6 1 SdiA-regulated DsbC_N PF10411.4 KLO06852.1 - 0.0027 16.9 10.6 1.4e+02 1.8 0.0 10.1 12 0 0 12 12 12 0 Disulfide bond isomerase protein N-terminus AAA_16 PF13191.1 KLO06852.1 - 0.0068 16.4 0.0 0.025 14.5 0.0 2.0 1 0 0 1 1 1 1 AAA ATPase domain PQQ_3 PF13570.1 KLO06852.1 - 0.022 14.9 31.5 0.69 10.2 0.1 9.9 5 4 6 11 11 11 0 PQQ-like domain AAA_29 PF13555.1 KLO06852.1 - 0.023 14.2 0.1 0.077 12.5 0.0 1.9 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_17 PF13207.1 KLO06852.1 - 0.025 15.3 0.2 0.09 13.5 0.1 2.0 2 0 0 2 2 1 0 AAA domain AAA_23 PF13476.1 KLO06852.1 - 0.06 13.6 0.0 0.16 12.2 0.0 1.6 2 0 0 2 2 1 0 AAA domain Arch_ATPase PF01637.13 KLO06852.1 - 0.085 12.5 0.0 0.24 11.0 0.0 1.8 1 0 0 1 1 1 0 Archaeal ATPase NB-ARC PF00931.17 KLO06852.1 - 0.11 11.3 0.1 0.28 10.0 0.0 1.6 2 0 0 2 2 2 0 NB-ARC domain Sec1 PF00995.18 KLO06852.1 - 0.11 11.0 0.0 0.17 10.4 0.0 1.2 1 0 0 1 1 1 0 Sec1 family AAA_22 PF13401.1 KLO06852.1 - 0.13 12.3 0.0 0.5 10.4 0.0 2.0 2 0 0 2 2 1 0 AAA domain APS_kinase PF01583.15 KLO06852.1 - 0.15 11.7 0.0 0.33 10.5 0.0 1.6 1 0 0 1 1 1 0 Adenylylsulphate kinase DDE_Tnp_4 PF13359.1 KLO06853.1 - 2.1e-19 69.6 0.0 2.9e-19 69.2 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease DUF641 PF04859.7 KLO06854.1 - 0.019 14.6 0.9 0.051 13.3 0.6 1.7 1 0 0 1 1 1 0 Plant protein of unknown function (DUF641) TTKRSYEDQ PF10212.4 KLO06854.1 - 0.11 11.4 1.0 0.16 10.8 0.7 1.2 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein APG6 PF04111.7 KLO06854.1 - 1 8.3 3.8 2.1 7.3 2.6 1.5 1 0 0 1 1 1 0 Autophagy protein Apg6 RHINO PF15319.1 KLO06855.1 - 0.038 13.7 0.3 0.053 13.3 0.2 1.2 1 0 0 1 1 1 0 RAD9, RAD1, HUS1-interacting nuclear orphan protein WW PF00397.21 KLO06856.1 - 8.4e-13 47.9 9.2 5.6e-07 29.3 3.6 2.4 2 0 0 2 2 2 2 WW domain RhoGAP PF00620.22 KLO06857.1 - 2.5e-27 95.3 0.0 4.5e-27 94.5 0.0 1.4 1 0 0 1 1 1 1 RhoGAP domain MyTH4 PF00784.12 KLO06857.1 - 4.7e-27 94.1 0.0 9.1e-27 93.2 0.0 1.5 1 0 0 1 1 1 1 MyTH4 domain Pro_3_hydrox_C PF05373.6 KLO06858.1 - 0.034 14.1 1.0 1.1 9.3 0.1 2.6 2 0 0 2 2 2 0 L-proline 3-hydroxylase, C-terminal CBFD_NFYB_HMF PF00808.18 KLO06858.1 - 0.48 10.5 6.1 2.6 8.1 0.1 3.1 3 0 0 3 3 3 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Pkinase_Tyr PF07714.12 KLO06861.1 - 1.1e-42 145.9 0.0 1.5e-42 145.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 KLO06861.1 - 3.7e-41 141.0 0.0 5.5e-41 140.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.1 KLO06861.1 - 0.00048 19.1 0.0 0.00067 18.7 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 KLO06861.1 - 0.0012 18.6 0.1 0.0026 17.5 0.1 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.17 KLO06861.1 - 0.042 13.2 0.1 0.12 11.6 0.0 1.8 2 0 0 2 2 2 0 RIO1 family EzrA PF06160.7 KLO06862.1 - 0.0077 14.4 0.7 0.013 13.7 0.3 1.4 1 1 0 1 1 1 1 Septation ring formation regulator, EzrA SPO22 PF08631.5 KLO06862.1 - 0.011 14.7 0.0 0.022 13.8 0.0 1.4 1 0 0 1 1 1 0 Meiosis protein SPO22/ZIP4 like Sipho_Gp157 PF05565.6 KLO06862.1 - 0.025 14.1 0.1 0.045 13.3 0.1 1.3 1 0 0 1 1 1 0 Siphovirus Gp157 DUF4618 PF15397.1 KLO06862.1 - 0.08 12.2 0.4 0.14 11.5 0.2 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4618) PqqD PF05402.7 KLO06862.1 - 0.1 12.6 0.1 1.4 8.9 0.0 2.8 4 1 0 4 4 4 0 Coenzyme PQQ synthesis protein D (PqqD) MerR-DNA-bind PF09278.6 KLO06862.1 - 0.13 12.7 0.1 5 7.6 0.0 2.5 2 0 0 2 2 2 0 MerR, DNA binding FlgN PF05130.7 KLO06862.1 - 1.4 9.1 7.1 3.8 7.7 4.2 2.1 1 1 1 2 2 2 0 FlgN protein Peptidase_C12 PF01088.16 KLO06863.1 - 1.9e-55 187.3 0.0 3.2e-55 186.6 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 Med31 PF05669.7 KLO06864.1 - 8.4e-36 121.8 3.8 1.1e-35 121.4 2.6 1.1 1 0 0 1 1 1 1 SOH1 Nod_GRP PF07806.6 KLO06864.1 - 0.0016 18.0 3.7 0.008 15.7 0.1 2.4 2 0 0 2 2 2 1 Nodule-specific GRP repeat Spt5-NGN PF03439.8 KLO06865.1 - 5.6e-07 29.2 0.0 1.2e-06 28.1 0.0 1.6 1 0 0 1 1 1 1 Early transcription elongation factor of RNA pol II, NGN section KOW PF00467.24 KLO06865.1 - 0.00012 21.6 25.8 0.042 13.5 0.2 5.8 5 0 0 5 5 5 3 KOW motif K_channel_TID PF07941.6 KLO06865.1 - 0.091 12.9 2.9 0.058 13.6 0.4 1.8 2 0 0 2 2 2 0 Potassium channel Kv1.4 tandem inactivation domain zf-MYND PF01753.13 KLO06866.1 - 1.9e-09 37.2 11.0 4.5e-09 36.0 7.6 1.7 1 0 0 1 1 1 1 MYND finger zf-Mss51 PF13824.1 KLO06866.1 - 0.17 11.7 3.2 0.49 10.2 2.3 1.8 1 0 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 zf-MYND PF01753.13 KLO06867.1 - 3.1e-09 36.5 10.5 5.9e-09 35.6 7.3 1.4 1 0 0 1 1 1 1 MYND finger Ecl1 PF12855.2 KLO06867.1 - 0.041 13.1 0.6 0.15 11.3 0.4 1.9 1 0 0 1 1 1 0 Life-span regulatory factor Clp_N PF02861.15 KLO06867.1 - 1.3 8.9 5.5 34 4.4 0.3 3.4 3 0 0 3 3 3 0 Clp amino terminal domain adh_short PF00106.20 KLO06868.1 - 1.9e-06 27.9 0.2 6.2e-06 26.2 0.1 1.8 1 1 0 1 1 1 1 short chain dehydrogenase HgmA PF04209.8 KLO06869.1 - 1.2e-161 537.9 0.1 1.4e-161 537.6 0.1 1.0 1 0 0 1 1 1 1 homogentisate 1,2-dioxygenase zf-MYND PF01753.13 KLO06870.1 - 3.3e-08 33.2 14.8 6.4e-08 32.3 10.3 1.5 1 0 0 1 1 1 1 MYND finger Ecl1 PF12855.2 KLO06870.1 - 0.052 12.8 1.6 0.12 11.6 1.1 1.6 1 0 0 1 1 1 0 Life-span regulatory factor 4HBT PF03061.17 KLO06870.1 - 0.1 12.7 0.0 0.2 11.8 0.0 1.5 1 0 0 1 1 1 0 Thioesterase superfamily zf-Mss51 PF13824.1 KLO06870.1 - 0.82 9.5 8.5 0.19 11.6 2.9 2.2 3 0 0 3 3 3 0 Zinc-finger of mitochondrial splicing suppressor 51 ketoacyl-synt PF00109.21 KLO06872.1 - 6e-67 225.7 0.5 1.2e-66 224.7 0.3 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 KLO06872.1 - 2.6e-48 165.0 0.0 1e-47 163.0 0.0 2.1 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.17 KLO06872.1 - 1e-36 125.3 0.5 2.1e-36 124.3 0.3 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain PS-DH PF14765.1 KLO06872.1 - 8.3e-26 90.8 0.0 1.4e-25 90.1 0.0 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase PP-binding PF00550.20 KLO06872.1 - 5.1e-18 65.0 3.1 2.2e-08 34.2 0.2 2.8 2 0 0 2 2 2 2 Phosphopantetheine attachment site Thioesterase PF00975.15 KLO06872.1 - 1.1e-17 65.0 0.0 5.1e-17 62.8 0.0 2.2 1 1 0 1 1 1 1 Thioesterase domain Abhydrolase_6 PF12697.2 KLO06872.1 - 1.1e-08 35.2 0.7 2.2e-05 24.4 0.0 3.4 3 0 0 3 3 3 2 Alpha/beta hydrolase family Thiolase_N PF00108.18 KLO06872.1 - 2e-06 26.9 0.1 4.9e-06 25.7 0.1 1.6 1 0 0 1 1 1 1 Thiolase, N-terminal domain Abhydrolase_5 PF12695.2 KLO06872.1 - 2.4e-05 24.1 0.7 0.04 13.6 0.0 3.1 3 0 0 3 3 3 2 Alpha/beta hydrolase family Abhydrolase_3 PF07859.8 KLO06872.1 - 0.012 15.2 0.0 0.024 14.1 0.0 1.5 1 0 0 1 1 1 0 alpha/beta hydrolase fold YqzH PF14164.1 KLO06873.1 - 0.1 12.5 0.0 0.15 11.9 0.0 1.3 1 0 0 1 1 1 0 YqzH-like protein Zn_clus PF00172.13 KLO06876.1 - 0.00051 19.8 8.3 0.00089 19.1 5.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF1192 PF06698.6 KLO06877.1 - 0.05 13.4 0.3 0.14 11.9 0.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1192) CTK3 PF12243.3 KLO06878.1 - 5.2e-30 103.9 0.0 7.1e-30 103.4 0.0 1.2 1 0 0 1 1 1 1 CTD kinase subunit gamma CTK3 CTK3_C PF12350.3 KLO06878.1 - 1.6e-14 53.6 14.8 1.3e-13 50.7 10.3 2.1 1 1 0 1 1 1 1 CTD kinase subunit gamma CTK3 C-terminus UbiA PF01040.13 KLO06879.1 - 1.8e-16 60.1 13.4 2.4e-16 59.7 9.3 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family PfkB PF00294.19 KLO06880.1 - 2.4e-11 43.3 0.0 4.8e-07 29.2 0.0 3.3 2 1 2 4 4 4 2 pfkB family carbohydrate kinase BTB PF00651.26 KLO06881.1 - 0.0003 20.7 0.0 0.0007 19.5 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain HDOD PF08668.7 KLO06885.1 - 0.074 12.3 0.0 0.11 11.7 0.0 1.3 1 0 0 1 1 1 0 HDOD domain TUG-UBL1 PF11470.3 KLO06886.1 - 0.0011 18.8 0.0 0.0021 17.9 0.0 1.4 1 0 0 1 1 1 1 GLUT4 regulating protein TUG DNA_pol_B_thumb PF14791.1 KLO06887.1 - 0.12 12.1 0.2 0.2 11.3 0.2 1.5 1 1 0 1 1 1 0 DNA polymerase beta thumb WD40 PF00400.27 KLO06889.1 - 0.065 13.1 0.2 0.66 9.9 0.1 2.4 2 0 0 2 2 2 0 WD domain, G-beta repeat Imm3 PF14425.1 KLO06890.1 - 0.11 12.4 0.1 0.21 11.5 0.1 1.4 1 0 0 1 1 1 0 Immunity protein Imm3 CABIT PF12736.2 KLO06893.1 - 0.095 11.7 0.0 0.12 11.3 0.0 1.1 1 0 0 1 1 1 0 Cell-cycle sustaining, positive selection, Polyoma_lg_T_C PF06431.6 KLO06900.1 - 0.12 11.0 0.1 0.16 10.6 0.1 1.1 1 0 0 1 1 1 0 Polyomavirus large T antigen C-terminus G6PD_C PF02781.11 KLO06901.1 - 2.9e-123 410.4 0.0 5.3e-123 409.5 0.0 1.4 2 0 0 2 2 2 1 Glucose-6-phosphate dehydrogenase, C-terminal domain G6PD_N PF00479.17 KLO06901.1 - 2.3e-62 210.4 0.1 3.9e-62 209.7 0.1 1.4 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, NAD binding domain IPK PF03770.11 KLO06901.1 - 0.044 13.4 0.2 0.8 9.3 0.1 2.1 2 0 0 2 2 2 0 Inositol polyphosphate kinase GFO_IDH_MocA PF01408.17 KLO06901.1 - 0.15 12.6 0.0 0.46 11.0 0.0 1.8 2 0 0 2 2 2 0 Oxidoreductase family, NAD-binding Rossmann fold LON PF02190.11 KLO06902.1 - 6.6e-21 74.9 0.0 1.1e-20 74.2 0.0 1.3 1 0 0 1 1 1 1 ATP-dependent protease La (LON) domain zf-C3HC4_2 PF13923.1 KLO06902.1 - 8.5e-08 32.1 11.4 8.5e-08 32.1 7.9 2.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 KLO06902.1 - 3.3e-07 30.0 19.2 0.00016 21.4 7.6 2.9 2 1 0 2 2 2 2 zinc finger of C3HC4-type, RING zf-C3HC4_3 PF13920.1 KLO06902.1 - 3.5e-07 29.7 8.1 3.5e-07 29.7 5.6 2.9 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KLO06902.1 - 4.2e-07 29.7 12.7 4.2e-07 29.7 8.8 2.7 2 0 0 2 2 2 1 Ring finger domain zf-RING_5 PF14634.1 KLO06902.1 - 1.6e-06 27.7 10.3 1.6e-06 27.7 7.1 2.8 3 0 0 3 3 3 2 zinc-RING finger domain zf-C3HC4 PF00097.20 KLO06902.1 - 4.6e-06 26.1 19.4 6.4e-06 25.7 7.7 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.1 KLO06902.1 - 0.00061 19.3 3.1 0.00061 19.3 2.2 2.6 3 0 0 3 3 3 1 RING/Ubox like zinc-binding domain zf-RING_6 PF14835.1 KLO06902.1 - 0.00067 19.3 1.6 0.0016 18.2 1.1 1.6 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-RING_UBOX PF13445.1 KLO06902.1 - 0.0043 16.7 3.7 0.0043 16.7 2.5 2.9 2 1 0 2 2 2 1 RING-type zinc-finger zf-rbx1 PF12678.2 KLO06902.1 - 0.025 14.6 5.7 0.073 13.1 4.0 1.8 1 0 0 1 1 1 0 RING-H2 zinc finger zf-P11 PF03854.9 KLO06902.1 - 0.27 10.7 8.3 0.79 9.2 5.7 1.8 1 0 0 1 1 1 0 P-11 zinc finger zf-Apc11 PF12861.2 KLO06902.1 - 0.57 10.0 5.6 0.26 11.1 1.8 2.0 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger DDE_1 PF03184.14 KLO06903.1 - 1.1e-22 80.2 0.0 1.6e-22 79.7 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_3 PF13358.1 KLO06903.1 - 5.2e-06 26.2 0.0 7.2e-06 25.8 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease DUF1682 PF07946.9 KLO06905.1 - 1.6e-67 227.6 0.3 1.9e-67 227.4 0.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1682) Stork_head PF10264.4 KLO06906.1 - 0.11 12.6 0.0 0.2 11.8 0.0 1.3 1 0 0 1 1 1 0 Winged helix Storkhead-box1 domain DUF3818 PF12825.2 KLO06907.1 - 4.3e-111 370.8 0.1 7.2e-111 370.1 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function in PX-proteins (DUF3818) PXB PF12828.2 KLO06907.1 - 7.9e-26 90.2 1.3 1.7e-25 89.1 0.9 1.6 1 0 0 1 1 1 1 PX-associated PX PF00787.19 KLO06907.1 - 2.6e-10 40.0 0.0 8.2e-10 38.4 0.0 1.9 1 0 0 1 1 1 1 PX domain Cnd1_N PF12922.2 KLO06907.1 - 0.042 13.4 2.1 0.39 10.3 0.1 2.6 2 0 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1, N-term Pkinase PF00069.20 KLO06908.1 - 8.4e-64 215.2 0.3 9.2e-43 146.2 0.1 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 KLO06908.1 - 2.5e-28 98.8 0.2 2.7e-21 75.8 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kdo PF06293.9 KLO06908.1 - 9.7e-05 21.5 0.1 0.00096 18.2 0.0 2.2 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 KLO06908.1 - 0.00014 20.9 0.0 0.00052 19.0 0.0 2.0 1 1 0 1 1 1 1 Kinase-like APH PF01636.18 KLO06908.1 - 0.00039 20.2 0.1 0.016 14.9 0.1 2.5 1 1 1 2 2 2 1 Phosphotransferase enzyme family Pkinase_C PF00433.19 KLO06908.1 - 0.0011 19.4 0.2 0.0031 17.9 0.1 1.9 2 0 0 2 2 2 1 Protein kinase C terminal domain RIO1 PF01163.17 KLO06908.1 - 0.013 14.8 0.0 0.048 13.0 0.0 1.9 1 0 0 1 1 1 0 RIO1 family Pox_ser-thr_kin PF05445.6 KLO06908.1 - 0.021 13.6 0.0 0.037 12.8 0.0 1.3 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Seadorna_VP7 PF07387.6 KLO06908.1 - 0.047 12.5 0.0 0.075 11.8 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Mid1 PF12929.2 KLO06909.1 - 1.4e-70 238.1 0.0 1.7e-70 237.9 0.0 1.1 1 0 0 1 1 1 1 Stretch-activated Ca2+-permeable channel component Fz PF01392.17 KLO06909.1 - 0.062 13.6 2.5 1.4 9.2 0.3 2.3 2 0 0 2 2 2 0 Fz domain GST_N_3 PF13417.1 KLO06910.1 - 1.7e-13 50.6 0.0 3e-13 49.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 KLO06910.1 - 1.1e-10 41.3 0.0 1.8e-10 40.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 KLO06910.1 - 0.018 15.1 0.0 0.042 14.0 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 KLO06910.1 - 0.057 13.3 0.0 0.1 12.4 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 KLO06910.1 - 0.087 12.8 0.0 0.13 12.2 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain DUF1211 PF06736.6 KLO06911.1 - 0.0064 16.6 0.7 0.018 15.1 0.5 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF1211) HLH PF00010.21 KLO06914.1 - 0.00039 20.0 0.9 0.00039 20.0 0.6 2.4 3 0 0 3 3 3 1 Helix-loop-helix DNA-binding domain Med3 PF11593.3 KLO06914.1 - 3.1 6.9 6.9 3.5 6.7 4.8 1.0 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal DUF566 PF04484.7 KLO06915.1 - 0.68 9.3 5.4 1 8.8 3.8 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF566) TPR_11 PF13414.1 KLO06917.1 - 1.6e-10 40.4 0.0 1.6e-10 40.4 0.0 2.4 4 0 0 4 4 4 1 TPR repeat TPR_1 PF00515.23 KLO06917.1 - 2.5e-06 26.8 0.0 0.01 15.4 0.0 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.12 KLO06917.1 - 2.9e-05 23.6 4.9 0.031 14.1 0.0 3.8 4 0 0 4 4 4 2 Tetratricopeptide repeat UBA PF00627.26 KLO06917.1 - 0.00012 21.7 0.0 0.00023 20.8 0.0 1.5 1 0 0 1 1 1 1 UBA/TS-N domain TPR_12 PF13424.1 KLO06917.1 - 0.012 15.5 1.2 0.15 12.0 0.0 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_16 PF13432.1 KLO06917.1 - 0.016 15.8 0.0 0.016 15.8 0.0 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat DnaJ PF00226.26 KLO06917.1 - 0.069 12.8 0.0 0.16 11.7 0.0 1.5 1 0 0 1 1 1 0 DnaJ domain TPR_7 PF13176.1 KLO06917.1 - 0.079 12.7 0.1 0.65 9.9 0.0 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF4449 PF14613.1 KLO06922.1 - 5.1e-25 88.2 0.1 5.1e-25 88.2 0.1 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF4449) Lipoprotein_7 PF01540.11 KLO06924.1 - 0.00017 20.7 0.3 0.00028 20.0 0.2 1.3 1 0 0 1 1 1 1 Adhesin lipoprotein DUF2959 PF11172.3 KLO06924.1 - 0.0092 15.7 0.1 0.48 10.1 0.0 2.4 1 1 1 2 2 2 2 Protein of unknown function (DUF2959) KAR9 PF08580.5 KLO06924.1 - 0.013 13.7 0.1 0.027 12.7 0.0 1.5 1 0 0 1 1 1 0 Yeast cortical protein KAR9 ALIX_LYPXL_bnd PF13949.1 KLO06924.1 - 0.014 14.4 0.1 0.056 12.3 0.0 2.0 1 1 1 2 2 2 0 ALIX V-shaped domain binding to HIV DASH_Dad2 PF08654.5 KLO06924.1 - 0.098 12.6 0.0 0.87 9.6 0.0 2.5 2 1 0 2 2 2 0 DASH complex subunit Dad2 Lipase_3 PF01764.20 KLO06925.1 - 1.2e-19 70.3 0.0 1.9e-19 69.6 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_5 PF12695.2 KLO06925.1 - 0.013 15.2 0.1 0.022 14.5 0.0 1.7 2 1 0 2 2 2 0 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KLO06925.1 - 0.021 14.7 0.0 0.064 13.1 0.0 1.9 2 0 0 2 2 2 0 Alpha/beta hydrolase family Cutinase PF01083.17 KLO06925.1 - 0.15 11.7 0.0 0.27 10.9 0.0 1.4 1 0 0 1 1 1 0 Cutinase Alpha-amylase PF00128.19 KLO06926.1 - 4.7e-104 348.1 0.3 7e-104 347.6 0.2 1.2 1 0 0 1 1 1 1 Alpha amylase, catalytic domain hDGE_amylase PF14701.1 KLO06926.1 - 0.014 14.3 0.0 0.023 13.5 0.0 1.2 1 0 0 1 1 1 0 glucanotransferase domain of human glycogen debranching enzyme CSTF_C PF14304.1 KLO06927.1 - 9.2e-06 24.8 2.5 5.7e-05 22.3 0.6 2.5 2 0 0 2 2 2 1 Transcription termination and cleavage factor C-terminal CSTF2_hinge PF14327.1 KLO06927.1 - 0.00044 20.2 2.9 0.00044 20.2 2.0 2.5 2 1 0 2 2 2 1 Hinge domain of cleavage stimulation factor subunit 2 EAP30 PF04157.11 KLO06927.1 - 0.19 10.8 0.0 0.26 10.4 0.0 1.1 1 0 0 1 1 1 0 EAP30/Vps36 family WXG100 PF06013.7 KLO06929.1 - 4.1e-05 23.4 1.8 0.0048 16.8 0.1 3.1 3 1 0 3 3 3 1 Proteins of 100 residues with WXG Apolipoprotein PF01442.13 KLO06929.1 - 0.0017 17.8 1.0 1.5 8.3 0.0 2.8 2 2 0 2 2 2 2 Apolipoprotein A1/A4/E domain Rsd_AlgQ PF04353.8 KLO06929.1 - 0.011 15.3 0.7 0.033 13.9 0.1 1.9 2 0 0 2 2 2 0 Regulator of RNA polymerase sigma(70) subunit, Rsd/AlgQ Baculo_PEP_C PF04513.7 KLO06929.1 - 0.059 13.1 0.0 11 5.8 0.0 2.5 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus CCDC-167 PF15188.1 KLO06929.1 - 0.26 11.2 3.0 3.4 7.6 0.0 3.4 3 1 1 4 4 4 0 Coiled-coil domain-containing protein 167 Apolipoprotein PF01442.13 KLO06930.1 - 0.0012 18.3 0.3 0.0016 18.0 0.2 1.4 1 1 0 1 1 1 1 Apolipoprotein A1/A4/E domain DUF2363 PF10155.4 KLO06930.1 - 0.047 13.6 0.0 0.093 12.6 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2363) CATSPERB PF15149.1 KLO06942.1 - 0.013 13.7 0.4 0.02 13.1 0.3 1.2 1 0 0 1 1 1 0 Cation channel sperm-associated protein subunit beta protein family Glyco_hydro_92 PF07971.7 KLO06944.1 - 4e-151 504.0 5.0 5.1e-151 503.7 3.5 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 Acyl-CoA_dh_M PF02770.14 KLO06946.1 - 0.014 14.8 0.0 0.031 13.7 0.0 1.6 1 0 0 1 1 1 0 Acyl-CoA dehydrogenase, middle domain Fungal_trans PF04082.13 KLO06950.1 - 4.1e-23 81.5 0.0 7.2e-23 80.7 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KLO06950.1 - 1.7e-10 40.6 11.2 4.6e-10 39.2 7.8 1.8 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain F-box-like PF12937.2 KLO06956.1 - 1.4e-08 34.3 3.4 7.5e-07 28.7 0.8 3.1 2 0 0 2 2 2 2 F-box-like RRM_1 PF00076.17 KLO06957.1 - 3.7e-52 173.8 0.4 8.2e-19 67.0 0.0 4.5 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KLO06957.1 - 1.1e-46 156.7 0.1 1.2e-15 57.1 0.0 4.5 4 0 0 4 4 4 4 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KLO06957.1 - 1.1e-27 95.6 0.0 7.5e-10 38.5 0.0 4.7 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 KLO06957.1 - 6.7e-07 28.9 0.0 0.0011 18.6 0.0 3.6 3 0 0 3 3 3 1 Nup53/35/40-type RNA recognition motif Nup35_RRM PF05172.8 KLO06957.1 - 0.0009 18.9 0.0 0.33 10.7 0.0 2.8 2 1 0 2 2 2 1 Nup53/35/40-type RNA recognition motif Peptidase_M16 PF00675.15 KLO06958.1 - 4.1e-53 179.1 1.3 7.2e-53 178.3 0.2 1.9 2 1 0 2 2 2 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.16 KLO06958.1 - 1.2e-42 145.7 0.0 9.2e-41 139.5 0.0 2.4 3 0 0 3 3 3 2 Peptidase M16 inactive domain Peptidase_U40 PF10464.4 KLO06958.1 - 0.0078 15.6 0.1 0.024 14.0 0.0 1.8 2 0 0 2 2 2 1 Peptidase U40 ETF PF01012.16 KLO06959.1 - 1.6e-34 118.9 1.0 2.1e-34 118.5 0.7 1.1 1 0 0 1 1 1 1 Electron transfer flavoprotein domain ADH_zinc_N PF00107.21 KLO06959.1 - 0.11 12.1 0.0 0.21 11.1 0.0 1.4 1 0 0 1 1 1 0 Zinc-binding dehydrogenase DUF2207 PF09972.4 KLO06960.1 - 0.00057 18.5 0.0 0.0007 18.2 0.0 1.1 1 0 0 1 1 1 1 Predicted membrane protein (DUF2207) LEAP-2 PF07359.6 KLO06961.1 - 0.046 13.3 0.1 0.065 12.8 0.1 1.3 1 0 0 1 1 1 0 Liver-expressed antimicrobial peptide 2 precursor (LEAP-2) EI24 PF07264.6 KLO06961.1 - 0.073 12.4 0.0 0.091 12.1 0.0 1.1 1 0 0 1 1 1 0 Etoposide-induced protein 2.4 (EI24) Helicase_C_2 PF13307.1 KLO06962.1 - 1.1e-52 178.3 0.1 3.6e-52 176.6 0.0 2.0 2 0 0 2 2 2 1 Helicase C-terminal domain DEAD_2 PF06733.10 KLO06962.1 - 1.7e-34 118.7 0.0 8.7e-34 116.4 0.0 2.2 1 1 0 1 1 1 1 DEAD_2 DEAD PF00270.24 KLO06962.1 - 0.002 17.6 0.2 0.18 11.3 0.0 2.9 2 2 0 2 2 2 1 DEAD/DEAH box helicase ResIII PF04851.10 KLO06962.1 - 0.0023 17.7 0.4 0.26 11.1 0.0 2.9 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit AAA_22 PF13401.1 KLO06962.1 - 0.0065 16.6 0.0 7.2 6.7 0.0 2.9 2 0 0 2 2 2 2 AAA domain AAA_30 PF13604.1 KLO06962.1 - 0.015 14.8 0.1 0.11 12.0 0.0 2.4 2 1 0 2 2 2 0 AAA domain T2SE PF00437.15 KLO06962.1 - 0.016 14.1 0.0 0.031 13.1 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein PhoH PF02562.11 KLO06962.1 - 0.038 13.2 0.0 0.74 9.0 0.0 2.2 2 0 0 2 2 2 0 PhoH-like protein AAA_19 PF13245.1 KLO06962.1 - 0.092 12.5 0.0 0.56 9.9 0.0 2.4 2 0 0 2 2 2 0 Part of AAA domain Ribosomal_L23eN PF03939.8 KLO06963.1 - 1.1e-18 67.0 10.9 1.1e-18 67.0 7.5 2.3 2 1 1 3 3 3 1 Ribosomal protein L23, N-terminal domain Ribosomal_L23 PF00276.15 KLO06963.1 - 2e-17 62.9 0.5 2e-17 62.9 0.4 1.9 2 0 0 2 2 2 1 Ribosomal protein L23 ASL_C PF08328.6 KLO06963.1 - 0.00036 20.3 0.2 0.00086 19.1 0.0 1.6 2 0 0 2 2 2 1 Adenylosuccinate lyase C-terminal YihI PF04220.7 KLO06963.1 - 0.073 12.4 1.4 0.11 11.8 1.0 1.3 1 0 0 1 1 1 0 Der GTPase activator (YihI) Pneumo_att_G PF05539.6 KLO06963.1 - 0.25 10.6 3.5 0.27 10.5 2.4 1.0 1 0 0 1 1 1 0 Pneumovirinae attachment membrane glycoprotein G Nipped-B_C PF12830.2 KLO06964.1 - 1.3e-48 165.1 2.0 3.6e-48 163.6 0.4 2.6 3 0 0 3 3 3 1 Sister chromatid cohesion C-terminus Cohesin_HEAT PF12765.2 KLO06964.1 - 7.9e-12 44.8 2.5 7.9e-12 44.8 1.8 4.1 4 0 0 4 4 4 1 HEAT repeat associated with sister chromatid cohesion HEAT_2 PF13646.1 KLO06964.1 - 0.00024 21.3 5.3 0.0023 18.1 0.0 4.5 3 1 1 4 4 4 1 HEAT repeats HEAT PF02985.17 KLO06964.1 - 0.0057 16.6 4.0 0.21 11.7 0.0 4.3 4 0 0 4 4 4 1 HEAT repeat Cnd1 PF12717.2 KLO06964.1 - 0.022 14.6 2.5 0.23 11.2 0.0 3.7 3 1 1 4 4 4 0 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.1 KLO06964.1 - 0.048 14.1 3.9 48 4.6 0.0 4.7 4 0 0 4 4 4 0 HEAT-like repeat Hpt PF01627.18 KLO06965.1 - 1e-11 44.6 0.1 1.6e-11 44.0 0.1 1.4 1 1 0 1 1 1 1 Hpt domain EHN PF06441.7 KLO06966.1 - 5e-35 119.8 0.5 1.3e-34 118.4 0.0 1.9 2 0 0 2 2 2 1 Epoxide hydrolase N terminus Abhydrolase_6 PF12697.2 KLO06966.1 - 1.8e-11 44.3 0.5 3.8e-11 43.2 0.4 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KLO06966.1 - 1.5e-05 24.6 0.3 2.6e-05 23.9 0.0 1.5 2 0 0 2 2 2 1 alpha/beta hydrolase fold OCD_Mu_crystall PF02423.10 KLO06967.1 - 7.2e-35 120.2 3.5 4.9e-34 117.5 2.4 2.0 1 1 0 1 1 1 1 Ornithine cyclodeaminase/mu-crystallin family Shikimate_DH PF01488.15 KLO06967.1 - 0.0037 17.3 0.0 0.014 15.5 0.0 1.9 1 1 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Transket_pyr PF02779.19 KLO06968.1 - 1.5e-65 220.0 0.0 2.4e-65 219.3 0.0 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain E1_dh PF00676.15 KLO06968.1 - 1.9e-58 197.5 0.0 2.6e-58 197.0 0.0 1.2 1 0 0 1 1 1 1 Dehydrogenase E1 component CoA_transf_3 PF02515.12 KLO06969.1 - 1.9e-63 213.1 0.0 2.4e-63 212.8 0.0 1.1 1 0 0 1 1 1 1 CoA-transferase family III Peptidase_S9 PF00326.16 KLO06971.1 - 4.1e-43 147.0 0.0 5.9e-43 146.5 0.0 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 KLO06971.1 - 1e-10 41.5 0.0 2.2e-10 40.4 0.0 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KLO06971.1 - 1.6e-10 41.2 0.3 1e-09 38.6 0.2 2.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family DLH PF01738.13 KLO06971.1 - 6.5e-10 38.6 0.7 4e-09 36.0 0.5 2.0 1 1 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_2 PF02230.11 KLO06971.1 - 3.2e-08 33.3 0.1 0.006 16.0 0.0 2.3 1 1 1 2 2 2 2 Phospholipase/Carboxylesterase Abhydrolase_3 PF07859.8 KLO06971.1 - 2.1e-05 24.2 0.1 8e-05 22.3 0.1 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_4 PF08386.5 KLO06971.1 - 5.4e-05 23.0 0.0 0.00018 21.3 0.0 1.8 2 0 0 2 2 2 1 TAP-like protein FSH1 PF03959.8 KLO06971.1 - 0.00032 20.2 0.0 0.0005 19.5 0.0 1.3 1 0 0 1 1 1 1 Serine hydrolase (FSH1) BAAT_C PF08840.6 KLO06971.1 - 0.00088 19.0 0.0 0.0017 18.1 0.0 1.4 1 0 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal DPPIV_N PF00930.16 KLO06971.1 - 0.0078 14.8 0.1 2.4 6.6 0.0 2.2 2 0 0 2 2 2 2 Dipeptidyl peptidase IV (DPP IV) N-terminal region PD40 PF07676.7 KLO06971.1 - 0.0089 15.6 0.1 0.025 14.2 0.1 1.8 1 0 0 1 1 1 1 WD40-like Beta Propeller Repeat DUF4350 PF14258.1 KLO06971.1 - 0.018 15.2 0.0 3.6 7.8 0.0 3.4 4 0 0 4 4 3 0 Domain of unknown function (DUF4350) Esterase_phd PF10503.4 KLO06971.1 - 0.019 14.1 0.1 0.043 13.0 0.1 1.5 1 0 0 1 1 1 0 Esterase PHB depolymerase Esterase PF00756.15 KLO06971.1 - 0.026 13.9 0.0 0.041 13.2 0.0 1.3 1 0 0 1 1 1 0 Putative esterase PAF-AH_p_II PF03403.8 KLO06971.1 - 0.1 10.8 0.0 0.19 10.0 0.0 1.3 1 0 0 1 1 1 0 Platelet-activating factor acetylhydrolase, isoform II TetR_C_7 PF14246.1 KLO06971.1 - 0.59 10.3 2.5 11 6.3 0.1 3.2 3 0 0 3 3 3 0 AefR-like transcriptional repressor, C-terminal region RRM_1 PF00076.17 KLO06972.1 - 4.7e-10 38.9 0.0 1.2e-09 37.7 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KLO06972.1 - 4.7e-06 26.4 0.0 1.2e-05 25.1 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) PWI PF01480.12 KLO06972.1 - 1.8e-05 24.7 0.1 5.6e-05 23.1 0.1 1.8 1 0 0 1 1 1 1 PWI domain RRM_5 PF13893.1 KLO06972.1 - 0.0016 18.2 0.0 0.003 17.3 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF494 PF04361.8 KLO06972.1 - 0.026 14.2 0.4 0.026 14.2 0.3 2.2 3 0 0 3 3 3 0 Protein of unknown function (DUF494) Mating_C PF12737.2 KLO06974.1 - 7.1 5.4 7.2 0.8 8.5 1.5 1.8 2 0 0 2 2 2 0 C-terminal domain of homeodomain 1 Methyltransf_31 PF13847.1 KLO06976.1 - 3.5e-13 49.3 0.0 7.6e-13 48.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KLO06976.1 - 4.7e-12 46.4 0.1 1.2e-11 45.1 0.1 1.7 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 KLO06976.1 - 6.3e-11 41.9 0.3 1.3e-10 40.9 0.2 1.4 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_26 PF13659.1 KLO06976.1 - 8.6e-11 41.9 0.2 2.6e-10 40.3 0.1 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 KLO06976.1 - 2.6e-10 40.6 0.0 7.8e-10 39.1 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KLO06976.1 - 2.7e-08 33.3 0.1 6.2e-08 32.1 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_23 PF13489.1 KLO06976.1 - 1.4e-06 28.0 0.0 1.2e-05 25.1 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 KLO06976.1 - 9.8e-06 25.8 0.0 2.3e-05 24.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_9 PF08003.6 KLO06976.1 - 4.1e-05 22.4 0.0 6.3e-05 21.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Methyltransf_12 PF08242.7 KLO06976.1 - 8.9e-05 22.8 0.0 0.00024 21.5 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Met_10 PF02475.11 KLO06976.1 - 0.00013 21.6 0.0 0.00024 20.7 0.0 1.3 1 0 0 1 1 1 1 Met-10+ like-protein UPF0020 PF01170.13 KLO06976.1 - 0.00041 19.9 0.0 0.00067 19.2 0.0 1.3 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 CMAS PF02353.15 KLO06976.1 - 0.00055 19.1 0.0 0.0013 17.8 0.0 1.6 2 0 0 2 2 2 1 Mycolic acid cyclopropane synthetase Cons_hypoth95 PF03602.10 KLO06976.1 - 0.00097 18.5 0.1 0.0016 17.8 0.0 1.3 1 0 0 1 1 1 1 Conserved hypothetical protein 95 TehB PF03848.9 KLO06976.1 - 0.0021 17.2 0.0 0.0043 16.2 0.0 1.5 1 1 0 1 1 1 1 Tellurite resistance protein TehB PCMT PF01135.14 KLO06976.1 - 0.0025 17.4 0.0 0.0042 16.6 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_32 PF13679.1 KLO06976.1 - 0.018 14.6 0.0 0.034 13.8 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain PRMT5 PF05185.11 KLO06976.1 - 0.07 12.0 0.2 0.48 9.2 0.0 2.2 2 1 0 2 2 2 0 PRMT5 arginine-N-methyltransferase Retinal PF15449.1 KLO06976.1 - 0.41 8.2 10.6 0.66 7.5 7.3 1.2 1 0 0 1 1 1 0 Retinal protein DIOX_N PF14226.1 KLO06979.1 - 7.8e-32 110.2 0.0 1.3e-31 109.5 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 KLO06979.1 - 6.7e-19 68.0 0.0 1.2e-18 67.1 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily XPG_I_2 PF12813.2 KLO06980.1 - 1.9e-08 34.0 0.0 4e-08 33.0 0.0 1.5 1 0 0 1 1 1 1 XPG domain containing XPG_N PF00752.12 KLO06980.1 - 0.00038 20.6 0.0 0.00096 19.3 0.0 1.7 1 1 0 1 1 1 1 XPG N-terminal domain TrbH PF07283.6 KLO06980.1 - 0.07 12.9 0.0 0.16 11.8 0.0 1.5 1 0 0 1 1 1 0 Conjugal transfer protein TrbH Sigma70_ner PF04546.8 KLO06980.1 - 8.1 5.9 8.3 15 5.1 5.7 1.4 1 0 0 1 1 1 0 Sigma-70, non-essential region Aldo_ket_red PF00248.16 KLO06981.1 - 8.5e-56 188.8 0.1 1e-55 188.6 0.1 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family DUF908 PF06012.7 KLO06982.1 - 0.046 13.0 0.4 0.049 12.9 0.3 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) CsbD PF05532.7 KLO06983.1 - 0.00095 18.7 1.8 0.0026 17.4 1.3 1.7 1 0 0 1 1 1 1 CsbD-like CsbD PF05532.7 KLO06984.1 - 2.2e-06 27.2 0.2 6.2e-06 25.8 0.1 1.7 1 0 0 1 1 1 1 CsbD-like AAA PF00004.24 KLO06985.1 - 2.5e-41 140.9 0.0 5.5e-41 139.8 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 KLO06985.1 - 0.0001 22.3 0.0 0.009 16.0 0.0 2.5 1 1 1 2 2 2 1 AAA ATPase domain RuvB_N PF05496.7 KLO06985.1 - 0.00021 20.4 0.0 0.00045 19.3 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_5 PF07728.9 KLO06985.1 - 0.00039 20.1 0.3 0.0068 16.1 0.2 2.6 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 KLO06985.1 - 0.00053 19.9 0.9 0.0036 17.2 0.0 2.5 2 1 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.1 KLO06985.1 - 0.0013 18.8 0.3 0.05 13.7 0.2 2.4 1 1 0 1 1 1 1 AAA domain PhoH PF02562.11 KLO06985.1 - 0.0014 17.8 0.0 0.024 13.8 0.0 2.3 2 0 0 2 2 2 1 PhoH-like protein Mg_chelatase PF01078.16 KLO06985.1 - 0.0078 15.3 0.1 0.028 13.5 0.1 1.8 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_33 PF13671.1 KLO06985.1 - 0.0085 15.9 0.0 0.022 14.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 KLO06985.1 - 0.01 15.5 0.1 0.026 14.2 0.1 1.6 1 0 0 1 1 1 0 Part of AAA domain IstB_IS21 PF01695.12 KLO06985.1 - 0.015 14.7 0.1 0.029 13.7 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein DUF815 PF05673.8 KLO06985.1 - 0.021 13.7 0.0 0.045 12.6 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_17 PF13207.1 KLO06985.1 - 0.034 14.9 0.1 0.13 13.0 0.0 2.0 1 1 0 1 1 1 0 AAA domain AAA_11 PF13086.1 KLO06985.1 - 0.046 13.2 0.3 0.64 9.5 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.1 KLO06985.1 - 0.049 13.2 0.1 0.14 11.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain DUF1192 PF06698.6 KLO06985.1 - 0.057 13.2 0.3 0.16 11.7 0.2 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1192) AAA_25 PF13481.1 KLO06985.1 - 0.07 12.5 0.9 0.84 9.0 0.1 2.4 1 1 1 2 2 2 0 AAA domain CPT PF07931.7 KLO06985.1 - 0.11 12.1 0.0 0.22 11.1 0.0 1.5 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein Cyclin_N PF00134.18 KLO06986.1 - 1.9e-11 43.6 0.1 3.7e-10 39.4 0.0 2.3 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 KLO06986.1 - 0.013 15.4 0.1 0.054 13.4 0.0 2.1 1 1 0 1 1 1 0 Cyclin, C-terminal domain SapB_1 PF05184.10 KLO06986.1 - 0.11 12.3 0.3 0.48 10.3 0.0 2.1 2 0 0 2 2 2 0 Saposin-like type B, region 1 MBOAT_2 PF13813.1 KLO06987.1 - 5.6e-16 58.3 3.1 5.7e-16 58.3 0.5 2.3 2 0 0 2 2 2 1 Membrane bound O-acyl transferase family MBOAT PF03062.14 KLO06987.1 - 0.0095 15.0 5.6 0.025 13.7 3.9 1.8 1 1 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family Glyco_trans_4_4 PF13579.1 KLO06988.1 - 0.0019 18.3 2.5 0.0024 18.0 1.7 1.2 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_hydro_61 PF03443.9 KLO06991.1 - 2.1e-61 207.5 0.0 4e-61 206.6 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 CBM_1 PF00734.13 KLO06991.1 - 2e-08 33.7 14.0 5e-08 32.4 9.7 1.8 1 0 0 1 1 1 1 Fungal cellulose binding domain SLAIN PF15301.1 KLO06991.1 - 1.8 7.6 4.8 2.3 7.2 3.3 1.1 1 0 0 1 1 1 0 SLAIN motif-containing family PWI PF01480.12 KLO06992.1 - 2.4e-28 98.0 0.0 3.8e-28 97.4 0.0 1.3 1 0 0 1 1 1 1 PWI domain EMP24_GP25L PF01105.19 KLO06993.1 - 4.9e-40 137.2 0.0 5.6e-40 137.0 0.0 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Amino_oxidase PF01593.19 KLO06994.1 - 4.1e-20 72.2 0.1 5.3e-20 71.9 0.0 1.1 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 KLO06994.1 - 1.1e-11 44.5 0.0 1.1e-11 44.5 0.0 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 KLO06994.1 - 1.1e-09 37.6 0.1 1.1e-09 37.6 0.1 2.0 2 1 0 2 2 1 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 KLO06994.1 - 0.00023 20.9 0.0 0.00023 20.9 0.0 2.7 3 0 0 3 3 3 1 FAD-NAD(P)-binding Pyr_redox_3 PF13738.1 KLO06994.1 - 0.00028 21.0 0.0 0.00028 21.0 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 KLO06994.1 - 0.0019 17.3 0.0 0.0031 16.6 0.0 1.3 1 0 0 1 1 1 1 Thi4 family Pyr_redox PF00070.22 KLO06994.1 - 0.0096 16.3 0.0 0.0096 16.3 0.0 2.3 3 0 0 3 3 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 KLO06994.1 - 0.016 15.0 1.6 0.053 13.3 0.0 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 KLO06994.1 - 0.057 12.3 0.0 0.091 11.6 0.0 1.3 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) HI0933_like PF03486.9 KLO06994.1 - 0.075 11.4 0.2 0.14 10.6 0.0 1.5 2 0 0 2 2 2 0 HI0933-like protein Mqo PF06039.10 KLO06994.1 - 0.089 10.9 0.0 0.13 10.3 0.0 1.1 1 0 0 1 1 1 0 Malate:quinone oxidoreductase (Mqo) Trp_halogenase PF04820.9 KLO06994.1 - 0.15 10.7 0.1 0.21 10.1 0.0 1.2 1 0 0 1 1 1 0 Tryptophan halogenase FMO-like PF00743.14 KLO06994.1 - 0.34 9.0 1.0 0.93 7.6 0.0 1.9 2 0 0 2 2 2 0 Flavin-binding monooxygenase-like Sterol_MT_C PF08498.5 KLO06995.1 - 1.5e-25 88.9 0.0 2.3e-25 88.3 0.0 1.3 1 0 0 1 1 1 1 Sterol methyltransferase C-terminal Methyltransf_31 PF13847.1 KLO06995.1 - 2e-17 63.1 0.0 3.1e-17 62.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KLO06995.1 - 5.3e-17 62.0 0.0 8.6e-17 61.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 KLO06995.1 - 8.5e-15 54.5 0.0 1.2e-14 54.0 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_23 PF13489.1 KLO06995.1 - 2.2e-12 46.9 0.0 3.6e-12 46.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KLO06995.1 - 3.3e-12 46.9 0.0 1.1e-11 45.2 0.0 1.8 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KLO06995.1 - 8.8e-11 42.1 0.0 2e-10 41.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KLO06995.1 - 1.8e-10 40.8 0.0 4.4e-10 39.6 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KLO06995.1 - 4.1e-10 39.9 0.0 8e-10 38.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KLO06995.1 - 2.2e-08 33.4 0.0 3.9e-08 32.6 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.9 KLO06995.1 - 4.6e-05 22.8 0.0 8.7e-05 21.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain PCMT PF01135.14 KLO06995.1 - 7.2e-05 22.4 0.0 0.00012 21.7 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_15 PF09445.5 KLO06995.1 - 0.00012 21.6 0.0 0.00018 21.0 0.0 1.2 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase MetW PF07021.7 KLO06995.1 - 0.00051 19.4 0.0 0.00087 18.7 0.0 1.4 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_3 PF01596.12 KLO06995.1 - 0.0018 17.3 0.0 0.0028 16.7 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_24 PF13578.1 KLO06995.1 - 0.0066 17.2 0.0 0.017 15.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Spermine_synth PF01564.12 KLO06995.1 - 0.019 13.8 0.0 0.03 13.2 0.0 1.2 1 0 0 1 1 1 0 Spermine/spermidine synthase Met_10 PF02475.11 KLO06995.1 - 0.06 12.9 0.0 0.082 12.4 0.0 1.2 1 0 0 1 1 1 0 Met-10+ like-protein PrmA PF06325.8 KLO06995.1 - 0.065 12.3 0.0 0.1 11.7 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Aldo_ket_red PF00248.16 KLO06996.1 - 1.9e-54 184.4 0.1 5.6e-54 182.8 0.1 1.8 1 1 0 1 1 1 1 Aldo/keto reductase family Aldo_ket_red PF00248.16 KLO06997.1 - 1.1e-70 237.7 0.0 1.2e-70 237.5 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family HMGL-like PF00682.14 KLO06997.1 - 0.082 12.5 0.0 0.29 10.7 0.0 1.9 2 0 0 2 2 2 0 HMGL-like RHH_1 PF01402.16 KLO06997.1 - 0.16 11.8 0.9 0.81 9.6 0.1 2.4 2 0 0 2 2 2 0 Ribbon-helix-helix protein, copG family Aldo_ket_red PF00248.16 KLO06998.1 - 3.5e-69 232.7 0.0 4e-69 232.5 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family RHH_1 PF01402.16 KLO06998.1 - 0.013 15.3 0.6 0.55 10.2 0.1 2.6 2 0 0 2 2 2 0 Ribbon-helix-helix protein, copG family MAGE_N PF12440.3 KLO06999.1 - 0.035 14.3 1.4 0.2 11.9 0.2 2.1 2 0 0 2 2 2 0 Melanoma associated antigen family N terminal HAD PF12710.2 KLO07000.1 - 9.1e-14 52.0 0.0 1.3e-13 51.5 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 KLO07000.1 - 4.7e-07 30.1 0.1 1.9e-06 28.2 0.0 1.8 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase UMPH-1 PF05822.7 KLO07000.1 - 0.0003 20.1 0.0 0.00057 19.2 0.0 1.6 1 1 0 1 1 1 1 Pyrimidine 5'-nucleotidase (UMPH-1) Hydrolase PF00702.21 KLO07000.1 - 0.00082 19.8 1.3 0.014 15.7 0.5 2.9 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Peptidase_C23 PF05379.6 KLO07000.1 - 0.13 12.2 0.1 0.24 11.4 0.0 1.5 1 0 0 1 1 1 0 Carlavirus endopeptidase F-box-like PF12937.2 KLO07001.1 - 4.9e-05 22.9 2.2 6.3e-05 22.6 0.3 2.1 2 1 0 2 2 2 1 F-box-like F-box PF00646.28 KLO07001.1 - 0.0002 20.9 0.7 0.0011 18.5 0.5 2.3 1 1 0 1 1 1 1 F-box domain F-box-like PF12937.2 KLO07002.1 - 4e-07 29.6 5.1 5.4e-06 26.0 0.3 3.6 2 1 0 2 2 2 2 F-box-like F-box-like PF12937.2 KLO07004.1 - 7e-05 22.4 0.0 0.00023 20.8 0.0 2.0 1 0 0 1 1 1 1 F-box-like Aldo_ket_red PF00248.16 KLO07005.1 - 2.4e-14 52.8 0.1 2.6e-14 52.7 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Hexokinase_2 PF03727.11 KLO07005.1 - 0.04 13.1 0.1 0.06 12.5 0.0 1.3 1 1 0 1 1 1 0 Hexokinase RHH_1 PF01402.16 KLO07005.1 - 0.075 12.9 0.6 15 5.6 0.0 2.8 3 0 0 3 3 3 0 Ribbon-helix-helix protein, copG family Arm PF00514.18 KLO07006.1 - 0.0078 16.0 0.1 0.0078 16.0 0.0 4.2 4 0 0 4 4 4 1 Armadillo/beta-catenin-like repeat RIX1 PF08167.7 KLO07006.1 - 0.24 11.0 4.1 2 8.0 0.1 2.8 2 1 0 2 2 2 0 rRNA processing/ribosome biogenesis DUF1793 PF08760.6 KLO07007.1 - 7.8e-33 113.7 0.2 1.4e-32 112.9 0.2 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1793) Bac_rhamnosid PF05592.6 KLO07007.1 - 0.0012 17.2 0.1 0.0019 16.4 0.0 1.4 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase GBA2_N PF12215.3 KLO07007.1 - 0.023 13.8 0.1 0.044 12.9 0.1 1.4 1 0 0 1 1 1 0 beta-Glucocerebrosidase 2 N terminal Ninjurin PF04923.7 KLO07009.1 - 3.1 7.5 5.5 0.36 10.5 0.3 1.9 2 0 0 2 2 2 0 Ninjurin TMEM213 PF15192.1 KLO07010.1 - 0.43 10.6 2.0 4.6 7.3 0.0 3.1 3 0 0 3 3 3 0 TMEM213 family DUF2956 PF11169.3 KLO07012.1 - 0.047 13.6 3.5 0.06 13.3 2.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2956) Exo5 PF09810.4 KLO07013.1 - 1.3e-58 198.7 0.0 1.5e-51 175.5 0.0 2.4 1 1 1 2 2 2 2 Exonuclease V - a 5' deoxyribonuclease PDDEXK_1 PF12705.2 KLO07013.1 - 0.00018 20.9 0.2 0.0042 16.5 0.1 2.5 2 1 0 2 2 2 1 PD-(D/E)XK nuclease superfamily DUF2360 PF10152.4 KLO07013.1 - 0.061 13.6 2.3 0.37 11.0 0.3 2.4 2 0 0 2 2 2 0 Predicted coiled-coil domain-containing protein (DUF2360) Pkinase PF00069.20 KLO07014.1 - 2.1e-36 125.4 0.0 3.4e-36 124.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KLO07014.1 - 3.5e-27 95.1 0.0 5.1e-27 94.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KLO07014.1 - 0.0088 15.0 0.0 0.013 14.4 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 KLO07014.1 - 0.014 15.1 0.0 0.074 12.7 0.0 2.0 1 1 0 1 1 1 0 Phosphotransferase enzyme family HIT PF01230.18 KLO07015.1 - 1.4e-24 86.4 0.0 2.1e-24 85.9 0.0 1.3 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.3 KLO07015.1 - 1.1e-08 35.2 0.0 2e-08 34.4 0.0 1.4 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding DUF2484 PF10658.4 KLO07016.1 - 0.044 13.9 1.4 0.086 12.9 0.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2484) DUF1793 PF08760.6 KLO07018.1 - 1.2e-37 129.4 0.0 2.5e-37 128.3 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1793) GBA2_N PF12215.3 KLO07018.1 - 0.0047 16.1 0.1 0.0081 15.3 0.1 1.3 1 0 0 1 1 1 1 beta-Glucocerebrosidase 2 N terminal Bac_rhamnosid PF05592.6 KLO07018.1 - 0.034 12.3 0.0 0.053 11.7 0.0 1.2 1 0 0 1 1 1 0 Bacterial alpha-L-rhamnosidase PIG-P PF08510.7 KLO07019.1 - 2.2 7.9 9.4 0.1 12.2 0.6 2.2 1 1 0 2 2 2 0 PIG-P AAA PF00004.24 KLO07022.1 - 5.3e-61 204.6 0.0 1.9e-45 154.3 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 KLO07022.1 - 7.8e-08 32.5 0.1 0.0044 17.1 0.0 3.2 2 1 0 2 2 2 2 AAA domain AAA_5 PF07728.9 KLO07022.1 - 5.2e-06 26.2 0.0 0.015 15.0 0.0 3.1 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 KLO07022.1 - 1.2e-05 25.3 2.0 0.0063 16.5 0.1 4.5 2 2 0 4 4 4 1 AAA ATPase domain Sigma54_activ_2 PF14532.1 KLO07022.1 - 0.0001 22.3 0.0 0.38 10.7 0.0 2.7 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_17 PF13207.1 KLO07022.1 - 0.00011 22.9 0.0 0.008 16.9 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 KLO07022.1 - 0.00016 21.3 0.0 0.0045 16.7 0.0 2.7 2 0 0 2 2 2 1 Part of AAA domain AAA_25 PF13481.1 KLO07022.1 - 0.00022 20.7 0.3 0.0044 16.4 0.1 2.7 2 1 0 2 2 2 1 AAA domain AAA_18 PF13238.1 KLO07022.1 - 0.00027 21.2 0.0 0.14 12.4 0.0 2.5 2 0 0 2 2 2 1 AAA domain RuvB_N PF05496.7 KLO07022.1 - 0.0004 19.4 0.0 0.0045 16.0 0.0 2.4 3 0 0 3 3 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_2 PF07724.9 KLO07022.1 - 0.00051 20.0 0.0 0.012 15.5 0.0 2.6 2 1 0 2 2 2 1 AAA domain (Cdc48 subfamily) IstB_IS21 PF01695.12 KLO07022.1 - 0.00064 19.1 0.1 0.002 17.5 0.0 1.8 2 0 0 2 2 1 1 IstB-like ATP binding protein AAA_28 PF13521.1 KLO07022.1 - 0.00084 19.3 0.1 0.16 11.9 0.0 3.1 2 1 1 3 3 3 1 AAA domain RNA_helicase PF00910.17 KLO07022.1 - 0.0011 19.0 0.0 0.041 14.0 0.0 2.6 2 0 0 2 2 2 1 RNA helicase AAA_33 PF13671.1 KLO07022.1 - 0.0014 18.4 0.0 0.17 11.7 0.0 3.0 3 0 0 3 3 3 1 AAA domain KaiC PF06745.8 KLO07022.1 - 0.0019 17.3 0.0 0.0047 16.0 0.0 1.6 1 0 0 1 1 1 1 KaiC TIP49 PF06068.8 KLO07022.1 - 0.002 16.9 0.0 0.031 13.0 0.0 2.2 2 0 0 2 2 2 1 TIP49 C-terminus Myelin_MBP PF01669.12 KLO07022.1 - 0.0037 17.5 0.0 0.21 11.8 0.0 2.8 2 0 0 2 2 2 1 Myelin basic protein AAA_14 PF13173.1 KLO07022.1 - 0.0037 17.1 0.0 0.19 11.6 0.0 2.6 2 0 0 2 2 2 1 AAA domain Vps4_C PF09336.5 KLO07022.1 - 0.0065 16.3 0.1 0.83 9.5 0.0 2.6 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain Mg_chelatase PF01078.16 KLO07022.1 - 0.007 15.5 0.1 0.038 13.1 0.0 2.0 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI Cytidylate_kin2 PF13189.1 KLO07022.1 - 0.012 15.5 0.0 0.43 10.4 0.0 2.3 2 0 0 2 2 2 0 Cytidylate kinase-like family UPF0079 PF02367.12 KLO07022.1 - 0.023 14.3 0.0 0.77 9.3 0.0 2.4 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 Sigma54_activat PF00158.21 KLO07022.1 - 0.031 13.7 0.0 1.4 8.4 0.0 2.5 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_24 PF13479.1 KLO07022.1 - 0.035 13.6 0.5 0.091 12.3 0.1 1.9 2 0 0 2 2 1 0 AAA domain PhoH PF02562.11 KLO07022.1 - 0.038 13.2 0.0 0.073 12.2 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein NACHT PF05729.7 KLO07022.1 - 0.039 13.6 0.4 2.6 7.6 0.0 3.0 3 1 0 3 3 3 0 NACHT domain Parvo_NS1 PF01057.12 KLO07022.1 - 0.053 12.3 0.0 0.087 11.6 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_3 PF07726.6 KLO07022.1 - 0.06 12.9 0.0 0.45 10.1 0.0 2.3 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Zeta_toxin PF06414.7 KLO07022.1 - 0.09 11.8 0.0 0.47 9.5 0.0 2.1 2 0 0 2 2 2 0 Zeta toxin DUF815 PF05673.8 KLO07022.1 - 0.19 10.6 0.0 0.97 8.3 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF815) Gar1 PF04410.9 KLO07023.1 - 1.7e-41 141.2 1.1 3e-41 140.4 0.8 1.5 1 1 0 1 1 1 1 Gar1/Naf1 RNA binding region RPN7 PF10602.4 KLO07024.1 - 2.1e-39 134.7 0.2 3.3e-39 134.0 0.1 1.3 1 0 0 1 1 1 1 26S proteasome subunit RPN7 PCI PF01399.22 KLO07024.1 - 7.4e-16 58.3 0.5 3.1e-15 56.3 0.1 2.1 2 0 0 2 2 2 1 PCI domain PCI_Csn8 PF10075.4 KLO07024.1 - 9.9e-05 22.1 0.2 0.00049 19.8 0.0 2.2 2 0 0 2 2 2 1 COP9 signalosome, subunit CSN8 GGDN PF05165.7 KLO07024.1 - 0.00036 19.6 0.2 0.00061 18.9 0.1 1.3 1 0 0 1 1 1 1 GGDN family DUF2119 PF09892.4 KLO07024.1 - 0.066 12.4 0.3 0.19 11.0 0.1 1.8 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2119) TPR_12 PF13424.1 KLO07025.1 - 2.2 8.3 10.6 29 4.6 0.4 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat GMC_oxred_N PF00732.14 KLO07026.1 - 5.6e-61 206.2 0.0 7.2e-61 205.9 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 KLO07026.1 - 5.5e-35 120.7 0.0 9.1e-35 120.0 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.7 KLO07026.1 - 0.0016 17.4 0.0 0.0024 16.8 0.0 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein DAO PF01266.19 KLO07026.1 - 0.0019 17.2 0.1 0.011 14.7 0.0 2.0 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KLO07026.1 - 0.009 16.0 0.0 0.02 14.8 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 KLO07026.1 - 0.01 15.7 0.0 0.021 14.6 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 KLO07026.1 - 0.035 12.9 0.1 0.055 12.3 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain Thi4 PF01946.12 KLO07026.1 - 0.043 12.9 0.0 0.078 12.0 0.0 1.4 1 0 0 1 1 1 0 Thi4 family HI0933_like PF03486.9 KLO07026.1 - 0.065 11.6 0.0 0.12 10.8 0.0 1.4 1 0 0 1 1 1 0 HI0933-like protein Haemocyan_bet_s PF14830.1 KLO07026.1 - 0.11 12.2 0.0 0.27 10.9 0.0 1.6 1 0 0 1 1 1 0 Haemocyanin beta-sandwich FYVE_2 PF02318.11 KLO07027.1 - 0.011 15.6 2.8 0.024 14.5 1.9 1.5 1 0 0 1 1 1 0 FYVE-type zinc finger NAD_binding_4 PF07993.7 KLO07028.1 - 5.5e-35 120.4 0.0 8.6e-35 119.8 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.23 KLO07028.1 - 2.4e-32 111.8 0.0 3.8e-32 111.2 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme Epimerase PF01370.16 KLO07028.1 - 2.4e-07 30.4 0.0 4.1e-07 29.6 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.20 KLO07028.1 - 0.0031 17.7 0.0 0.0069 16.6 0.0 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site adh_short PF00106.20 KLO07028.1 - 0.0099 15.8 0.0 0.059 13.2 0.0 2.4 1 1 0 1 1 1 1 short chain dehydrogenase 3Beta_HSD PF01073.14 KLO07028.1 - 0.14 10.8 0.0 0.37 9.4 0.0 1.6 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family YABBY PF04690.8 KLO07029.1 - 1.4e-08 35.1 1.4 1.4e-08 35.1 1.0 1.4 1 1 0 1 1 1 1 YABBY protein HMG_box PF00505.14 KLO07029.1 - 1.2e-06 28.6 9.4 5.4e-06 26.5 6.5 2.0 1 1 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 KLO07029.1 - 0.0015 18.9 8.1 0.0015 18.9 5.6 2.0 2 1 0 2 2 2 1 HMG-box domain DUF1014 PF06244.7 KLO07029.1 - 0.0016 18.6 2.0 0.0016 18.6 1.4 2.2 1 1 1 2 2 2 1 Protein of unknown function (DUF1014) CBP4 PF07960.6 KLO07029.1 - 8.9 5.9 11.1 0.51 9.9 3.3 1.8 2 0 0 2 2 2 0 CBP4 Glyco_transf_90 PF05686.7 KLO07031.1 - 2.7e-12 46.1 1.5 5.3e-11 41.8 1.0 2.5 2 1 0 2 2 2 1 Glycosyl transferase family 90 DUF1054 PF06335.7 KLO07031.1 - 0.067 12.8 0.0 0.13 11.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1054) USP8_dimer PF08969.6 KLO07032.1 - 1.6e-07 31.2 0.1 3.2e-07 30.3 0.1 1.4 1 0 0 1 1 1 1 USP8 dimerisation domain JAB PF01398.16 KLO07033.1 - 5.6e-18 64.7 0.0 8.2e-18 64.2 0.0 1.2 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Prok-JAB PF14464.1 KLO07033.1 - 1.3e-08 34.3 0.0 2.7e-08 33.3 0.0 1.5 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain NPL4 PF05021.10 KLO07033.1 - 0.0042 16.3 0.0 0.006 15.7 0.0 1.2 1 0 0 1 1 1 1 NPL4 family adh_short PF00106.20 KLO07034.1 - 1.8e-29 102.7 0.1 2.5e-29 102.3 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KLO07034.1 - 3.8e-14 52.7 0.0 5.3e-14 52.2 0.0 1.2 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 KLO07034.1 - 5.9e-13 49.1 0.0 7.9e-13 48.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 KLO07034.1 - 0.023 14.7 0.1 0.035 14.0 0.0 1.5 1 0 0 1 1 1 0 NADH(P)-binding THF_DHG_CYH_C PF02882.14 KLO07034.1 - 0.073 12.1 0.1 0.36 9.8 0.0 1.9 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Eno-Rase_NADH_b PF12242.3 KLO07034.1 - 0.083 12.6 0.1 0.18 11.6 0.1 1.5 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase adh_short PF00106.20 KLO07035.1 - 2.8e-27 95.6 0.0 4.2e-27 95.1 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KLO07035.1 - 1.2e-13 51.0 0.0 2e-13 50.4 0.0 1.2 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 KLO07035.1 - 1.7e-09 37.8 0.0 2.3e-09 37.3 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 KLO07035.1 - 0.0026 17.2 0.0 0.0046 16.4 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family DAHP_synth_1 PF00793.15 KLO07036.1 - 1.6e-93 312.3 0.0 2e-93 312.0 0.0 1.0 1 0 0 1 1 1 1 DAHP synthetase I family RFamide_26RFa PF11109.3 KLO07036.1 - 0.089 12.6 0.0 0.22 11.4 0.0 1.7 1 0 0 1 1 1 0 Orexigenic neuropeptide Qrfp/P518 PIH1 PF08190.7 KLO07037.1 - 2.7e-29 102.6 0.0 3.9e-27 95.5 0.0 2.2 2 0 0 2 2 2 2 pre-RNA processing PIH1/Nop17 Sugar_tr PF00083.19 KLO07040.1 - 4.1e-21 75.0 16.0 9.5e-15 54.1 3.3 2.4 2 1 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 KLO07040.1 - 3.5e-19 68.7 40.4 3.7e-11 42.3 16.1 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2583 PF10762.4 KLO07040.1 - 0.049 13.7 0.3 0.18 11.9 0.2 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2583) Abhydrolase_6 PF12697.2 KLO07041.1 - 5.2e-12 46.1 0.7 1.5e-11 44.6 0.5 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KLO07041.1 - 5e-10 39.3 0.0 8.9e-10 38.4 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KLO07041.1 - 0.0039 16.7 0.2 0.54 9.7 0.1 2.5 2 1 1 3 3 3 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 KLO07041.1 - 0.0044 16.2 0.0 0.11 11.6 0.0 2.1 2 0 0 2 2 2 1 Prolyl oligopeptidase family Lipase_3 PF01764.20 KLO07041.1 - 0.007 15.9 0.0 0.012 15.1 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) DUF2974 PF11187.3 KLO07041.1 - 0.017 14.5 0.0 0.029 13.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Cutinase PF01083.17 KLO07041.1 - 0.069 12.8 0.0 0.12 12.1 0.0 1.3 1 0 0 1 1 1 0 Cutinase Thioesterase PF00975.15 KLO07041.1 - 0.09 12.9 0.0 0.18 12.0 0.0 1.4 1 0 0 1 1 1 0 Thioesterase domain CS PF04969.11 KLO07042.1 - 8e-10 39.1 0.1 1.2e-09 38.5 0.0 1.3 1 0 0 1 1 1 1 CS domain Phosphoprotein PF00922.12 KLO07042.1 - 0.18 11.0 0.9 0.21 10.7 0.0 1.5 2 0 0 2 2 2 0 Vesiculovirus phosphoprotein Fork_head_N PF08430.7 KLO07042.1 - 0.35 11.2 15.2 0.54 10.6 10.6 1.2 1 0 0 1 1 1 0 Forkhead N-terminal region Sporozoite_P67 PF05642.6 KLO07042.1 - 9.6 3.9 10.8 16 3.2 7.5 1.3 1 0 0 1 1 1 0 Sporozoite P67 surface antigen MFS_1 PF07690.11 KLO07043.1 - 3.2e-23 82.0 42.3 3.7e-15 55.5 17.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KLO07043.1 - 3.9e-16 58.6 24.1 2.8e-14 52.5 16.7 3.1 1 1 0 1 1 1 1 Sugar (and other) transporter DUF2583 PF10762.4 KLO07043.1 - 0.005 16.9 0.2 0.026 14.6 0.1 2.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2583) p450 PF00067.17 KLO07044.1 - 9.8e-72 241.9 0.0 1.1e-71 241.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 BPL_LplA_LipB PF03099.14 KLO07046.1 - 4.5e-07 29.9 0.0 8.3e-07 29.0 0.0 1.5 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family GTSE1_N PF15259.1 KLO07048.1 - 0.14 12.1 1.7 4.5 7.2 1.2 2.1 1 1 0 1 1 1 0 G-2 and S-phase expressed 1 FAM75 PF14650.1 KLO07049.1 - 0.12 11.7 0.5 0.12 11.7 0.3 1.0 1 0 0 1 1 1 0 FAM75 family 2-oxoacid_dh PF00198.18 KLO07051.1 - 5.6e-50 169.7 0.0 2e-49 167.9 0.0 1.8 1 1 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.17 KLO07051.1 - 4.5e-20 71.0 0.3 8.7e-20 70.1 0.2 1.5 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.12 KLO07051.1 - 6.6e-08 32.0 0.1 1.4e-07 31.0 0.1 1.6 1 0 0 1 1 1 1 e3 binding domain Biotin_lipoyl_2 PF13533.1 KLO07051.1 - 0.00011 21.7 0.6 0.00053 19.5 0.1 2.3 2 1 1 3 3 3 1 Biotin-lipoyl like HlyD_3 PF13437.1 KLO07051.1 - 0.00039 20.7 0.0 0.0031 17.8 0.0 2.2 1 1 1 2 2 2 1 HlyD family secretion protein HlyD_2 PF12700.2 KLO07051.1 - 0.0025 17.0 0.0 0.0035 16.5 0.0 1.1 1 0 0 1 1 1 1 HlyD family secretion protein Pyridox_oxidase PF01243.15 KLO07052.1 - 0.0041 17.1 0.0 0.013 15.5 0.0 1.9 1 1 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Pyridox_oxidase PF01243.15 KLO07053.1 - 5.5e-07 29.5 0.0 1e-06 28.6 0.0 1.5 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase DUF4117 PF13491.1 KLO07054.1 - 0.11 11.9 12.2 0.12 11.7 0.7 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4117) Tmemb_185A PF10269.4 KLO07054.1 - 3 7.4 11.9 1 8.9 3.0 2.7 1 1 2 3 3 3 0 Transmembrane Fragile-X-F protein DUF3328 PF11807.3 KLO07055.1 - 2.2e-10 40.6 0.1 2.6e-10 40.3 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) DUF4350 PF14258.1 KLO07055.1 - 0.13 12.5 0.0 0.25 11.5 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4350) AP_endonuc_2 PF01261.19 KLO07056.1 - 0.13 11.5 0.1 1.3 8.2 0.0 2.5 2 1 1 3 3 3 0 Xylose isomerase-like TIM barrel DUF1275 PF06912.6 KLO07059.1 - 1.1e-21 77.0 17.2 1.4e-21 76.7 12.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1275) Acyl_transf_3 PF01757.17 KLO07059.1 - 0.00073 18.4 14.7 0.0043 15.9 3.9 2.1 1 1 1 2 2 2 2 Acyltransferase family AA_permease_2 PF13520.1 KLO07059.1 - 0.018 13.5 6.3 0.034 12.6 4.4 1.4 1 0 0 1 1 1 0 Amino acid permease STE3 PF02076.10 KLO07060.1 - 9.4e-58 195.5 5.0 1.2e-57 195.2 3.4 1.1 1 0 0 1 1 1 1 Pheromone A receptor STE3 PF02076.10 KLO07061.1 - 2.4e-11 43.2 3.9 2.5e-11 43.2 2.7 1.0 1 0 0 1 1 1 1 Pheromone A receptor STE3 PF02076.10 KLO07062.1 - 5.1e-30 104.5 1.5 6.4e-30 104.2 1.0 1.1 1 0 0 1 1 1 1 Pheromone A receptor STE3 PF02076.10 KLO07064.1 - 7.6e-58 195.8 12.4 9.2e-58 195.5 8.6 1.1 1 0 0 1 1 1 1 Pheromone A receptor Neurensin PF14927.1 KLO07064.1 - 0.093 12.1 0.3 0.59 9.5 0.1 2.3 1 1 0 2 2 2 0 Neurensin STE3 PF02076.10 KLO07065.1 - 7.4e-57 192.5 10.4 8.7e-57 192.3 7.2 1.0 1 0 0 1 1 1 1 Pheromone A receptor Neurensin PF14927.1 KLO07065.1 - 0.014 14.7 0.1 0.2 11.0 0.1 2.2 2 0 0 2 2 2 0 Neurensin Rad60-SLD_2 PF13881.1 KLO07066.1 - 1e-13 51.1 0.0 1.6e-13 50.5 0.0 1.3 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.18 KLO07066.1 - 0.0027 17.0 0.0 0.014 14.7 0.0 2.0 1 1 0 1 1 1 1 Ubiquitin family Conotoxin PF02950.12 KLO07066.1 - 0.09 13.5 0.1 0.12 13.1 0.0 1.2 1 0 0 1 1 1 0 Conotoxin PfkB PF00294.19 KLO07067.1 - 2.6e-08 33.3 0.0 4.4e-08 32.6 0.0 1.3 1 0 0 1 1 1 1 pfkB family carbohydrate kinase GTSE1_N PF15259.1 KLO07069.1 - 0.029 14.3 1.0 0.05 13.5 0.7 1.4 1 0 0 1 1 1 0 G-2 and S-phase expressed 1 BNIP3 PF06553.7 KLO07069.1 - 0.048 13.0 8.3 0.025 13.9 1.4 2.3 1 1 1 2 2 2 0 BNIP3 Pex19 PF04614.7 KLO07069.1 - 0.078 12.5 0.1 2 7.9 0.0 2.0 1 1 1 2 2 2 0 Pex19 protein family AAA PF00004.24 KLO07070.1 - 3.4e-11 43.4 0.0 7.3e-11 42.3 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ArgK PF03308.11 KLO07070.1 - 0.0067 15.2 0.0 0.012 14.4 0.0 1.3 1 0 0 1 1 1 1 ArgK protein 2_5_RNA_ligase2 PF13563.1 KLO07070.1 - 0.092 12.4 0.2 2 8.1 0.1 2.6 3 0 0 3 3 3 0 2'-5' RNA ligase superfamily AAA_5 PF07728.9 KLO07070.1 - 0.1 12.3 0.0 1 9.0 0.0 2.4 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA PF00004.24 KLO07071.1 - 8.9e-11 42.1 0.0 1.9e-10 41.0 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ArgK PF03308.11 KLO07071.1 - 0.015 14.0 0.0 0.027 13.2 0.0 1.3 1 0 0 1 1 1 0 ArgK protein AAA_16 PF13191.1 KLO07071.1 - 0.046 13.6 0.3 0.25 11.3 0.2 2.4 1 1 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.1 KLO07071.1 - 0.2 11.8 0.7 7.1 6.7 0.0 3.1 2 1 1 3 3 3 0 AAA domain AAA PF00004.24 KLO07072.1 - 2.6e-10 40.5 0.0 1.1e-09 38.5 0.0 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 KLO07072.1 - 0.11 12.6 0.3 6 7.0 0.0 2.8 1 1 1 2 2 2 0 AAA domain AAA_16 PF13191.1 KLO07072.1 - 0.43 10.5 2.7 4.5 7.2 1.6 2.7 1 1 0 1 1 1 0 AAA ATPase domain Pkinase PF00069.20 KLO07075.1 - 2.8e-33 115.1 0.0 3.4e-25 88.6 0.0 2.1 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 KLO07075.1 - 1.5e-29 102.8 0.0 9.2e-19 67.5 0.0 2.1 1 1 1 2 2 2 2 Protein tyrosine kinase CENP-F_leu_zip PF10473.4 KLO07075.1 - 0.00014 21.7 4.7 0.00027 20.7 3.3 1.4 1 0 0 1 1 1 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 APH PF01636.18 KLO07075.1 - 0.0029 17.3 0.0 0.005 16.5 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Myosin_tail_1 PF01576.14 KLO07075.1 - 0.0071 14.1 1.1 0.0093 13.7 0.8 1.1 1 0 0 1 1 1 1 Myosin tail RIO1 PF01163.17 KLO07075.1 - 0.0076 15.6 0.0 0.018 14.3 0.0 1.6 2 0 0 2 2 2 1 RIO1 family FH2 PF02181.18 KLO07075.1 - 0.049 12.5 0.6 0.074 11.9 0.4 1.2 1 0 0 1 1 1 0 Formin Homology 2 Domain Reo_sigmaC PF04582.7 KLO07075.1 - 0.12 11.5 0.1 0.19 10.8 0.1 1.3 1 0 0 1 1 1 0 Reovirus sigma C capsid protein Syntaxin-6_N PF09177.6 KLO07075.1 - 0.14 12.5 0.8 0.29 11.5 0.3 1.7 2 0 0 2 2 2 0 Syntaxin 6, N-terminal FlaC_arch PF05377.6 KLO07075.1 - 0.48 10.3 2.4 11 6.0 0.2 2.6 2 1 0 3 3 3 0 Flagella accessory protein C (FlaC) Abhydrolase_6 PF12697.2 KLO07077.1 - 1e-24 87.7 0.6 1.2e-24 87.4 0.4 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KLO07077.1 - 3.2e-11 43.2 0.1 1.1e-10 41.4 0.1 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KLO07077.1 - 5.7e-09 35.8 0.1 9.6e-09 35.1 0.1 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 KLO07077.1 - 1.5e-06 27.9 0.0 2.7e-06 27.1 0.0 1.4 1 0 0 1 1 1 1 Putative lysophospholipase NmrA PF05368.8 KLO07079.1 - 1.1e-34 119.7 0.5 2.6e-23 82.4 0.0 2.1 1 1 1 2 2 2 2 NmrA-like family NAD_binding_10 PF13460.1 KLO07079.1 - 6.4e-07 29.5 0.5 2.6e-05 24.2 0.4 2.2 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 KLO07079.1 - 0.081 12.3 0.2 0.49 9.7 0.1 2.2 2 1 0 2 2 2 0 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 KLO07079.1 - 0.1 11.2 0.2 7.8 5.1 0.0 2.2 1 1 1 2 2 2 0 3-beta hydroxysteroid dehydrogenase/isomerase family Cullin PF00888.17 KLO07079.1 - 0.14 10.6 0.0 0.2 10.1 0.0 1.1 1 0 0 1 1 1 0 Cullin family NAD_binding_4 PF07993.7 KLO07079.1 - 0.15 11.0 0.0 0.21 10.4 0.0 1.2 1 0 0 1 1 1 0 Male sterility protein adh_short PF00106.20 KLO07079.1 - 0.15 11.9 0.0 0.2 11.5 0.0 1.2 1 0 0 1 1 1 0 short chain dehydrogenase Metallophos PF00149.23 KLO07080.1 - 2.9e-42 144.3 0.3 4.7e-42 143.6 0.2 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Mcp5_PH PF12814.2 KLO07082.1 - 6.7e-43 145.5 0.0 1.2e-42 144.7 0.0 1.4 1 0 0 1 1 1 1 Meiotic cell cortex C-terminal pleckstrin homology PH PF00169.24 KLO07082.1 - 0.044 13.9 0.0 0.097 12.8 0.0 1.6 1 0 0 1 1 1 0 PH domain GAS PF13851.1 KLO07082.1 - 0.97 8.5 28.7 3.5 6.7 11.0 3.5 3 0 0 3 3 3 0 Growth-arrest specific micro-tubule binding SNN_linker PF09050.5 KLO07086.1 - 0.049 13.1 0.1 0.049 13.1 0.1 1.9 2 0 0 2 2 2 0 Stannin unstructured linker Transglut_core2 PF13369.1 KLO07089.1 - 7.1e-09 35.3 0.0 1.3e-08 34.4 0.0 1.4 1 0 0 1 1 1 1 Transglutaminase-like superfamily F-box-like PF12937.2 KLO07089.1 - 0.032 13.9 0.1 0.1 12.3 0.1 1.9 1 0 0 1 1 1 0 F-box-like Peptidase_M16 PF00675.15 KLO07091.1 - 1.1e-41 142.0 0.0 2e-41 141.1 0.0 1.4 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.16 KLO07091.1 - 1.2e-36 126.1 0.0 4.5e-36 124.2 0.0 2.0 1 1 0 1 1 1 1 Peptidase M16 inactive domain Ceramidase PF05875.7 KLO07092.1 - 9.4e-72 241.2 11.2 1.1e-71 241.0 7.7 1.0 1 0 0 1 1 1 1 Ceramidase FHA PF00498.21 KLO07093.1 - 1.3e-16 60.4 0.0 2.4e-16 59.5 0.0 1.5 1 0 0 1 1 1 1 FHA domain MIP-T3 PF10243.4 KLO07093.1 - 8.4 4.7 32.1 11 4.3 22.2 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 SAS4 PF15460.1 KLO07095.1 - 2.5e-05 24.0 3.8 2.5e-05 24.0 2.6 1.8 2 0 0 2 2 2 1 Something about silencing, SAS, complex subunit 4 PEHE PF15275.1 KLO07095.1 - 0.00024 21.5 2.8 0.00024 21.5 1.9 3.2 4 0 0 4 4 4 1 PEHE domain Trypan_PARP PF05887.6 KLO07095.1 - 0.014 15.1 39.5 0.014 15.1 27.4 3.7 3 1 1 4 4 4 0 Procyclic acidic repetitive protein (PARP) Gar1 PF04410.9 KLO07096.1 - 2e-35 121.5 0.9 2e-35 121.5 0.6 2.4 3 0 0 3 3 3 1 Gar1/Naf1 RNA binding region CmcI PF04989.7 KLO07096.1 - 0.082 12.2 0.0 0.15 11.3 0.0 1.4 1 0 0 1 1 1 0 Cephalosporin hydroxylase EF_TS PF00889.14 KLO07097.1 - 1.4e-18 67.0 0.0 4e-18 65.5 0.0 1.7 1 1 1 2 2 2 1 Elongation factor TS UBA PF00627.26 KLO07097.1 - 0.00053 19.7 0.1 0.0011 18.7 0.1 1.5 1 0 0 1 1 1 1 UBA/TS-N domain C2-set_2 PF08205.7 KLO07097.1 - 0.025 14.4 0.0 0.048 13.5 0.0 1.4 1 0 0 1 1 1 0 CD80-like C2-set immunoglobulin domain Glyco_hydro_6 PF01341.12 KLO07098.1 - 2.5e-102 342.3 0.9 3.1e-102 342.0 0.6 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 6 zf-DHHC PF01529.15 KLO07099.1 - 6.1e-40 136.4 6.8 8.8e-40 135.9 4.7 1.2 1 0 0 1 1 1 1 DHHC palmitoyltransferase Transglut_core3 PF13471.1 KLO07099.1 - 0.096 12.4 0.6 0.2 11.4 0.4 1.5 1 0 0 1 1 1 0 Transglutaminase-like superfamily FA_desaturase PF00487.19 KLO07101.1 - 3.5e-16 59.4 11.7 6.4e-16 58.5 8.1 1.4 1 0 0 1 1 1 1 Fatty acid desaturase Cyt-b5 PF00173.23 KLO07101.1 - 5.8e-07 29.2 0.0 2.5e-06 27.2 0.0 2.1 1 1 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Secretin_N_2 PF07655.8 KLO07101.1 - 0.036 14.4 0.9 0.06 13.7 0.6 1.3 1 0 0 1 1 1 0 Secretin N-terminal domain DUF1764 PF08576.5 KLO07101.1 - 0.069 13.9 0.1 0.11 13.2 0.1 1.3 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF1764) DUF755 PF05501.6 KLO07101.1 - 1.6 8.7 9.2 2.5 8.1 6.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF755) Bromodomain PF00439.20 KLO07102.1 - 4.5e-44 148.2 5.6 3.9e-22 77.9 0.9 2.4 2 0 0 2 2 2 2 Bromodomain Lge1 PF11488.3 KLO07102.1 - 0.51 10.5 3.1 1.8 8.8 2.2 1.9 1 1 0 1 1 1 0 Transcriptional regulatory protein LGE1 AT_hook PF02178.14 KLO07102.1 - 2.8 7.8 12.1 0.13 12.0 3.9 2.4 2 0 0 2 2 2 0 AT hook motif YukC PF10140.4 KLO07103.1 - 0.17 10.4 0.5 0.28 9.7 0.3 1.3 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukC FWWh PF14922.1 KLO07104.1 - 0.036 13.5 0.5 0.089 12.2 0.4 1.6 1 1 0 1 1 1 0 Protein of unknown function Pyr_redox_3 PF13738.1 KLO07105.1 - 9.3e-18 65.0 0.0 1.9e-17 64.0 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KLO07105.1 - 2.6e-10 40.1 0.0 5.7e-10 39.0 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FMO-like PF00743.14 KLO07105.1 - 1e-09 37.1 0.7 1.3e-06 26.9 0.0 2.5 2 1 0 2 2 2 2 Flavin-binding monooxygenase-like K_oxygenase PF13434.1 KLO07105.1 - 0.0011 18.0 0.2 0.062 12.2 0.0 2.9 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.19 KLO07105.1 - 0.0018 17.2 0.0 0.16 10.8 0.0 2.5 2 1 1 3 3 3 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 KLO07105.1 - 0.0023 17.8 0.0 0.013 15.3 0.0 2.0 1 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 KLO07105.1 - 0.0061 16.3 0.0 0.048 13.4 0.0 2.3 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pkinase_Tyr PF07714.12 KLO07106.1 - 4.4e-33 114.4 0.0 5.6e-33 114.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 KLO07106.1 - 5.3e-32 110.9 0.0 7.1e-32 110.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.1 KLO07106.1 - 0.00097 18.1 0.0 0.0013 17.7 0.0 1.1 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 KLO07106.1 - 0.046 13.4 0.4 0.081 12.6 0.0 1.5 2 0 0 2 2 2 0 Phosphotransferase enzyme family zf-MYND PF01753.13 KLO07107.1 - 1.1e-07 31.5 15.2 2.2e-07 30.6 10.5 1.5 1 0 0 1 1 1 1 MYND finger zf-MYND PF01753.13 KLO07108.1 - 3.4e-08 33.2 14.1 6.9e-08 32.2 9.7 1.5 1 0 0 1 1 1 1 MYND finger zf-Mss51 PF13824.1 KLO07108.1 - 0.56 10.1 4.3 1.5 8.7 3.0 1.7 1 0 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 zf-MYND PF01753.13 KLO07110.1 - 5.2e-08 32.6 15.6 8.8e-08 31.8 10.8 1.4 1 0 0 1 1 1 1 MYND finger zf-MYND PF01753.13 KLO07111.1 - 1.7e-08 34.1 14.9 3.3e-08 33.2 10.3 1.5 1 0 0 1 1 1 1 MYND finger zf-MYND PF01753.13 KLO07112.1 - 1e-08 34.8 13.6 1.9e-08 34.0 9.4 1.5 1 0 0 1 1 1 1 MYND finger zf-Mss51 PF13824.1 KLO07112.1 - 0.36 10.7 4.4 0.78 9.6 3.1 1.5 1 0 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 zf-MYND PF01753.13 KLO07113.1 - 1.2e-08 34.7 13.4 2.3e-08 33.7 9.3 1.5 1 0 0 1 1 1 1 MYND finger zf-MYND PF01753.13 KLO07114.1 - 3.1e-09 36.5 13.3 6.4e-09 35.5 9.2 1.5 1 0 0 1 1 1 1 MYND finger zf-MYND PF01753.13 KLO07115.1 - 1.1e-07 31.6 16.0 1.9e-07 30.8 11.1 1.4 1 0 0 1 1 1 1 MYND finger zf-MYND PF01753.13 KLO07116.1 - 1.7e-09 37.3 13.5 3.2e-09 36.4 9.4 1.5 1 0 0 1 1 1 1 MYND finger PBP-Tp47_a PF14889.1 KLO07116.1 - 0.16 11.3 0.0 0.31 10.3 0.0 1.4 1 0 0 1 1 1 0 Penicillin-binding protein Tp47 domain a eIF-1a PF01176.14 KLO07117.1 - 0.14 11.6 0.0 0.3 10.5 0.0 1.5 1 0 0 1 1 1 0 Translation initiation factor 1A / IF-1 Pkinase PF00069.20 KLO07119.1 - 1.5e-41 142.2 0.0 2.1e-41 141.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KLO07119.1 - 1.8e-39 135.3 0.0 2.5e-39 134.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KLO07119.1 - 0.0007 18.6 0.0 0.0012 17.8 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 KLO07119.1 - 0.049 12.6 0.0 0.081 11.9 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KLO07119.1 - 0.15 11.7 0.0 0.26 10.9 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pkinase PF00069.20 KLO07120.1 - 3.2e-45 154.2 0.0 4.4e-45 153.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KLO07120.1 - 1.7e-40 138.7 0.0 2.3e-40 138.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KLO07120.1 - 6.8e-05 21.9 0.0 0.00019 20.4 0.0 1.6 1 1 0 1 1 1 1 Kinase-like APH PF01636.18 KLO07120.1 - 0.16 11.7 0.0 0.27 10.9 0.0 1.4 1 1 0 1 1 1 0 Phosphotransferase enzyme family ECH PF00378.15 KLO07121.1 - 1.9e-48 164.7 0.1 2.3e-48 164.4 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family DUF3366 PF11846.3 KLO07121.1 - 0.058 13.2 0.1 0.097 12.5 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3366) TPX2 PF06886.6 KLO07126.1 - 0.0001 22.2 21.0 0.00031 20.7 12.2 2.3 2 0 0 2 2 2 1 Targeting protein for Xklp2 (TPX2) DUF572 PF04502.8 KLO07126.1 - 0.0016 17.7 2.8 0.0018 17.5 2.0 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF572) PVL_ORF50 PF07768.6 KLO07126.1 - 0.05 13.5 6.6 0.058 13.3 3.7 1.7 2 0 0 2 2 2 0 PVL ORF-50-like family DUF2051 PF09738.4 KLO07126.1 - 4.6 6.4 12.8 0.12 11.6 4.5 1.5 2 0 0 2 2 2 0 Double stranded RNA binding protein (DUF2051) Peptidase_M76 PF09768.4 KLO07128.1 - 2.3e-38 131.3 0.1 2.9e-38 131.0 0.1 1.1 1 0 0 1 1 1 1 Peptidase M76 family SprT-like PF10263.4 KLO07128.1 - 0.071 12.7 2.4 0.093 12.3 1.4 1.6 1 1 0 1 1 1 0 SprT-like family Peptidase_MA_2 PF13485.1 KLO07128.1 - 0.099 12.6 0.3 0.18 11.8 0.2 1.4 1 0 0 1 1 1 0 Peptidase MA superfamily zf-H2C2_5 PF13909.1 KLO07128.1 - 3.3 8.1 8.3 0.92 9.8 1.8 2.5 2 0 0 2 2 2 0 C2H2-type zinc-finger domain Peptidase_S64 PF08192.6 KLO07131.1 - 4.8 5.3 8.0 10 4.3 5.5 1.4 1 0 0 1 1 1 0 Peptidase family S64 Helitron_like_N PF14214.1 KLO07134.1 - 8.3e-05 22.3 0.0 0.00012 21.8 0.0 1.3 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus Sec34 PF04136.10 KLO07134.1 - 0.063 12.9 0.1 0.1 12.2 0.1 1.3 1 0 0 1 1 1 0 Sec34-like family PIF1 PF05970.9 KLO07136.1 - 7.7e-08 31.6 0.0 1.7e-07 30.5 0.0 1.5 1 1 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.1 KLO07136.1 - 3e-06 26.9 0.0 4.8e-06 26.2 0.0 1.3 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 KLO07136.1 - 0.00013 21.6 0.0 0.0002 21.0 0.0 1.3 1 0 0 1 1 1 1 Part of AAA domain Zeta_toxin PF06414.7 KLO07136.1 - 0.0061 15.6 0.0 0.008 15.2 0.0 1.2 1 0 0 1 1 1 1 Zeta toxin Bac_DnaA PF00308.13 KLO07136.1 - 0.0086 15.7 0.1 0.079 12.5 0.0 2.0 2 0 0 2 2 2 1 Bacterial dnaA protein AAA PF00004.24 KLO07136.1 - 0.0096 16.1 0.2 0.042 14.0 0.1 2.0 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 KLO07136.1 - 0.05 13.3 0.1 0.2 11.3 0.0 1.9 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.12 KLO07136.1 - 0.07 12.5 0.1 0.15 11.4 0.0 1.6 2 0 0 2 2 2 0 IstB-like ATP binding protein NTPase_1 PF03266.10 KLO07136.1 - 0.11 12.1 0.0 0.73 9.5 0.0 2.0 2 0 0 2 2 2 0 NTPase AAA_11 PF13086.1 KLO07136.1 - 0.15 11.6 0.0 0.2 11.2 0.0 1.3 1 1 0 1 1 1 0 AAA domain AAA_22 PF13401.1 KLO07136.1 - 0.16 12.1 0.3 0.44 10.6 0.2 1.8 1 1 0 1 1 1 0 AAA domain Ribonuc_red_sm PF00268.16 KLO07137.1 - 1.2e-115 385.4 0.2 1.4e-115 385.1 0.1 1.0 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain Claudin_2 PF13903.1 KLO07139.1 - 0.021 14.4 0.3 0.038 13.6 0.2 1.4 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction F-box-like PF12937.2 KLO07139.1 - 0.034 13.8 0.2 0.081 12.6 0.2 1.6 1 0 0 1 1 1 0 F-box-like ResIII PF04851.10 KLO07139.1 - 0.16 11.8 0.0 0.26 11.0 0.0 1.3 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit Pyr_excise PF03013.9 KLO07140.1 - 0.12 12.1 0.1 0.24 11.1 0.1 1.5 1 0 0 1 1 1 0 Pyrimidine dimer DNA glycosylase ClpS PF02617.12 KLO07140.1 - 0.27 10.9 0.9 6.6 6.5 0.1 2.3 2 0 0 2 2 2 0 ATP-dependent Clp protease adaptor protein ClpS F-box-like PF12937.2 KLO07143.1 - 1.4e-06 27.9 0.0 4.7e-06 26.2 0.0 1.9 1 1 0 1 1 1 1 F-box-like LRR_4 PF12799.2 KLO07143.1 - 0.12 12.0 0.8 26 4.5 0.1 3.7 3 1 0 3 3 3 0 Leucine Rich repeats (2 copies) Pox_A3L PF05288.6 KLO07146.1 - 0.11 12.1 0.0 0.22 11.2 0.0 1.5 1 0 0 1 1 1 0 Poxvirus A3L Protein DUF3133 PF11331.3 KLO07147.1 - 0.036 13.6 0.1 0.24 10.9 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3133) Fungal_trans_2 PF11951.3 KLO07149.1 - 0.035 12.7 0.3 0.079 11.5 0.1 1.6 1 1 1 2 2 2 0 Fungal specific transcription factor domain TYW3 PF02676.9 KLO07149.1 - 0.21 10.7 1.0 0.39 9.8 0.6 1.5 1 1 0 1 1 1 0 Methyltransferase TYW3 MFS_1 PF07690.11 KLO07150.1 - 3.5e-29 101.6 27.8 3.5e-29 101.6 19.2 1.3 1 1 0 1 1 1 1 Major Facilitator Superfamily Peptidase_U4 PF03419.8 KLO07150.1 - 0.62 9.0 7.4 0.79 8.7 4.1 1.8 1 1 1 2 2 2 0 Sporulation factor SpoIIGA PhoD PF09423.5 KLO07151.1 - 1.7e-138 462.0 0.1 2e-138 461.7 0.1 1.0 1 0 0 1 1 1 1 PhoD-like phosphatase Terpene_synth_C PF03936.11 KLO07152.1 - 2.1e-16 60.0 0.0 2.6e-16 59.6 0.0 1.1 1 0 0 1 1 1 1 Terpene synthase family, metal binding domain Het-C PF07217.6 KLO07154.1 - 1e-219 730.7 0.0 1.3e-219 730.4 0.0 1.0 1 0 0 1 1 1 1 Heterokaryon incompatibility protein Het-C SKG6 PF08693.5 KLO07155.1 - 0.025 13.8 0.2 0.047 13.0 0.1 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain SKG6 PF08693.5 KLO07156.1 - 0.00025 20.2 2.4 0.00045 19.4 1.7 1.4 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Shisa PF13908.1 KLO07156.1 - 0.014 15.5 0.0 0.022 14.9 0.0 1.4 1 1 0 1 1 1 0 Wnt and FGF inhibitory regulator NfeD PF01957.13 KLO07156.1 - 0.056 13.5 0.9 0.077 13.1 0.6 1.2 1 0 0 1 1 1 0 NfeD-like C-terminal, partner-binding IncA PF04156.9 KLO07156.1 - 0.32 10.5 3.9 0.39 10.2 2.7 1.2 1 0 0 1 1 1 0 IncA protein COX8 PF02285.10 KLO07156.1 - 0.86 9.1 3.7 1.9 8.1 0.1 2.3 2 0 0 2 2 2 0 Cytochrome oxidase c subunit VIII CcmD PF04995.9 KLO07156.1 - 4 7.2 6.8 1.3 8.7 2.4 1.8 2 0 0 2 2 2 0 Heme exporter protein D (CcmD) DAG1 PF05454.6 KLO07156.1 - 4.7 6.3 5.7 0.49 9.5 0.1 1.9 2 0 0 2 2 2 0 Dystroglycan (Dystrophin-associated glycoprotein 1) F-box-like PF12937.2 KLO07157.1 - 1.1e-05 25.0 0.9 2.1e-05 24.1 0.0 2.0 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 KLO07157.1 - 0.0043 16.6 0.1 0.11 12.2 0.0 2.7 2 0 0 2 2 2 1 F-box domain HMG_box PF00505.14 KLO07158.1 - 9.3e-13 48.2 1.0 1.2e-12 47.9 0.7 1.1 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 KLO07158.1 - 3.5e-07 30.4 0.9 3.8e-07 30.3 0.6 1.1 1 0 0 1 1 1 1 HMG-box domain HMG_box_5 PF14887.1 KLO07158.1 - 0.024 14.4 0.1 0.026 14.3 0.1 1.1 1 0 0 1 1 1 0 HMG (high mobility group) box 5 DUF2057 PF09829.4 KLO07158.1 - 0.04 13.5 0.1 0.042 13.5 0.1 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2057) Death PF00531.17 KLO07158.1 - 0.12 12.1 0.0 0.22 11.2 0.0 1.5 1 0 0 1 1 1 0 Death domain Cellulase PF00150.13 KLO07159.1 - 1.9e-10 40.4 0.0 1.2e-09 37.8 0.0 1.9 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Zn_clus PF00172.13 KLO07161.1 - 0.00028 20.7 8.3 0.00045 20.0 5.8 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Zn_clus PF00172.13 KLO07162.1 - 2.2e-06 27.4 8.3 2.2e-06 27.4 5.7 1.5 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Zn_clus PF00172.13 KLO07163.1 - 1.5e-05 24.7 11.3 2.7e-05 23.9 7.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Zn_clus PF00172.13 KLO07165.1 - 3.2e-06 26.9 11.8 3.2e-06 26.9 8.2 1.7 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Zn_clus PF00172.13 KLO07168.1 - 3e-06 27.0 12.1 7.9e-06 25.6 8.4 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain LURAP PF14854.1 KLO07171.1 - 0.0017 18.0 0.3 0.0023 17.6 0.2 1.3 1 1 0 1 1 1 1 Leucine rich adaptor protein Zn_clus PF00172.13 KLO07172.1 - 1.8e-07 30.9 10.4 1.8e-07 30.9 7.2 2.3 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain GCHY-1 PF02649.9 KLO07172.1 - 0.2 10.8 0.8 0.25 10.5 0.6 1.1 1 0 0 1 1 1 0 Type I GTP cyclohydrolase folE2 Rot1 PF10681.4 KLO07175.1 - 2.7e-54 183.7 0.9 3.2e-54 183.5 0.6 1.0 1 0 0 1 1 1 1 Chaperone for protein-folding within the ER, fungal F-box-like PF12937.2 KLO07176.1 - 0.02 14.6 0.1 0.043 13.5 0.1 1.6 1 0 0 1 1 1 0 F-box-like Sigma70_ner PF04546.8 KLO07176.1 - 4.9 6.7 13.0 2.3 7.7 0.2 2.4 2 0 0 2 2 2 0 Sigma-70, non-essential region CcmD PF04995.9 KLO07177.1 - 0.56 9.9 1.3 0.93 9.2 0.9 1.3 1 0 0 1 1 1 0 Heme exporter protein D (CcmD) Proteasome PF00227.21 KLO07178.1 - 1.3e-33 115.8 0.1 1.9e-33 115.3 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit DUF2121 PF09894.4 KLO07178.1 - 0.08 12.2 0.5 5.1 6.3 0.0 2.4 3 0 0 3 3 3 0 Uncharacterized protein conserved in archaea (DUF2121) S1_2 PF13509.1 KLO07178.1 - 0.11 12.4 0.0 0.24 11.3 0.0 1.5 1 0 0 1 1 1 0 S1 domain Pkinase PF00069.20 KLO07181.1 - 1.6e-40 138.9 0.0 2.7e-40 138.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KLO07181.1 - 2.8e-38 131.4 0.0 4.6e-38 130.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KLO07181.1 - 0.00038 19.5 0.0 0.00066 18.7 0.0 1.3 1 0 0 1 1 1 1 Kinase-like HARP PF07443.8 KLO07181.1 - 0.19 11.1 2.1 0.33 10.3 0.0 2.3 2 0 0 2 2 2 0 HepA-related protein (HARP) Transferrin PF00405.12 KLO07182.1 - 0.041 12.7 0.0 0.062 12.1 0.0 1.1 1 0 0 1 1 1 0 Transferrin DUF805 PF05656.9 KLO07182.1 - 2.2 8.1 12.5 1.4e+02 2.3 8.6 2.9 1 1 0 1 1 1 0 Protein of unknown function (DUF805) DUF2976 PF11190.3 KLO07182.1 - 9.5 5.8 10.2 1.1 8.8 0.2 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF2976) Fim-adh_lectin PF09222.5 KLO07184.1 - 0.002 17.4 0.0 0.014 14.6 0.0 2.1 2 0 0 2 2 2 1 Fimbrial adhesin F17-AG, lectin domain Metal_CEHH PF14455.1 KLO07184.1 - 0.078 12.3 0.1 0.13 11.6 0.1 1.3 1 0 0 1 1 1 0 Predicted metal binding domain DUF4231 PF14015.1 KLO07186.1 - 0.011 15.7 3.9 0.015 15.3 2.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4231) RNA_pol_Rpb1_7 PF04990.7 KLO07187.1 - 0.043 13.5 0.6 0.32 10.7 0.1 2.2 2 0 0 2 2 2 0 RNA polymerase Rpb1, domain 7 Ftsk_gamma PF09397.5 KLO07187.1 - 0.085 12.5 0.1 0.2 11.4 0.0 1.5 1 0 0 1 1 1 0 Ftsk gamma domain Bul1_C PF04426.7 KLO07188.1 - 0.023 13.9 0.1 0.056 12.6 0.1 1.6 2 0 0 2 2 2 0 Bul1 C terminus HisG PF01634.13 KLO07189.1 - 4.2e-48 163.0 0.1 6.6e-48 162.3 0.0 1.3 1 0 0 1 1 1 1 ATP phosphoribosyltransferase HisG_C PF08029.6 KLO07189.1 - 5.1e-27 93.6 0.0 9.5e-27 92.7 0.0 1.5 1 0 0 1 1 1 1 HisG, C-terminal domain NMT1 PF09084.6 KLO07189.1 - 0.0001 21.9 0.1 0.00015 21.4 0.0 1.2 1 0 0 1 1 1 1 NMT1/THI5 like Methyltransf_20 PF12147.3 KLO07189.1 - 0.059 12.2 0.0 0.092 11.5 0.0 1.2 1 0 0 1 1 1 0 Putative methyltransferase UQ_con PF00179.21 KLO07190.1 - 2.6e-41 140.3 0.0 3.3e-41 139.9 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UBA_3 PF09288.5 KLO07190.1 - 9.1e-15 53.9 0.2 1.6e-14 53.1 0.1 1.4 1 0 0 1 1 1 1 Fungal ubiquitin-associated domain Prok-E2_B PF14461.1 KLO07190.1 - 3.4e-05 23.6 0.0 5.2e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic E2 family B DUF217 PF02697.9 KLO07192.1 - 0.11 12.8 0.2 1.1 9.5 0.0 2.2 1 1 1 2 2 2 0 Uncharacterized ACR, COG1753 DUF3626 PF12294.3 KLO07193.1 - 0.031 13.2 0.0 0.054 12.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3626) DUF4331 PF14224.1 KLO07194.1 - 0.13 11.3 0.0 0.14 11.2 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4331) peroxidase PF00141.18 KLO07197.1 - 2.8e-29 102.2 0.0 7.1e-29 100.9 0.0 1.7 2 1 0 2 2 2 1 Peroxidase DUF3415 PF11895.3 KLO07197.1 - 2e-23 82.0 1.7 5.1e-23 80.7 1.2 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF3415) Cloacin_immun PF03513.9 KLO07197.1 - 0.13 12.3 0.0 0.25 11.3 0.0 1.5 1 0 0 1 1 1 0 Cloacin immunity protein DUF2762 PF10960.3 KLO07202.1 - 0.13 11.9 1.6 1.8 8.3 0.0 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF2762) BTB PF00651.26 KLO07206.1 - 0.00012 22.0 0.0 0.00029 20.7 0.0 1.6 1 1 0 1 1 1 1 BTB/POZ domain BTB PF00651.26 KLO07207.1 - 1e-05 25.5 0.0 2e-05 24.5 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain BTB PF00651.26 KLO07208.1 - 3e-08 33.6 0.0 5.4e-08 32.8 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain BTB PF00651.26 KLO07209.1 - 7.1e-06 25.9 0.0 1.6e-05 24.8 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain BTB PF00651.26 KLO07210.1 - 0.0001 22.2 0.0 0.00023 21.0 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain BTB PF00651.26 KLO07211.1 - 5.9e-06 26.2 0.0 1.1e-05 25.3 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain BTB PF00651.26 KLO07212.1 - 2.1e-06 27.7 0.0 4.8e-06 26.5 0.0 1.6 1 0 0 1 1 1 1 BTB/POZ domain BTB PF00651.26 KLO07213.1 - 0.00028 20.8 0.0 0.00047 20.1 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain BTB PF00651.26 KLO07214.1 - 0.0002 21.2 0.0 0.00069 19.5 0.0 1.9 2 0 0 2 2 2 1 BTB/POZ domain Sda PF08970.5 KLO07214.1 - 0.11 12.0 0.2 5.4 6.5 0.0 2.4 1 1 1 2 2 2 0 Sporulation inhibitor A BTB PF00651.26 KLO07215.1 - 0.009 15.9 0.0 0.26 11.2 0.0 2.4 2 0 0 2 2 2 1 BTB/POZ domain RAMP PF04901.8 KLO07215.1 - 0.016 14.9 0.2 1.4 8.6 0.0 3.0 3 0 0 3 3 3 0 Receptor activity modifying family PsaD PF02531.11 KLO07215.1 - 0.074 12.2 0.0 0.15 11.2 0.0 1.5 1 1 0 1 1 1 0 PsaD BTB PF00651.26 KLO07216.1 - 0.00051 19.9 0.0 0.00099 19.0 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain BTB PF00651.26 KLO07217.1 - 1.7e-05 24.7 0.1 4.1e-05 23.5 0.0 1.6 2 0 0 2 2 2 1 BTB/POZ domain BTB PF00651.26 KLO07218.1 - 1.4e-06 28.2 0.0 5.6e-06 26.3 0.0 1.9 2 0 0 2 2 2 1 BTB/POZ domain BTB PF00651.26 KLO07219.1 - 3.7e-07 30.1 0.0 6.9e-07 29.2 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain BTB PF00651.26 KLO07220.1 - 9.9e-06 25.5 0.0 1.4e-05 25.0 0.0 1.1 1 0 0 1 1 1 1 BTB/POZ domain DUF1419 PF07215.6 KLO07221.1 - 0.0073 16.1 0.0 0.013 15.3 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1419) BTB PF00651.26 KLO07221.1 - 0.023 14.6 0.0 0.048 13.6 0.0 1.5 1 0 0 1 1 1 0 BTB/POZ domain BTB PF00651.26 KLO07222.1 - 2e-09 37.4 0.7 1.9e-08 34.2 0.1 2.2 1 1 1 2 2 2 1 BTB/POZ domain Chlam_OMP6 PF03504.8 KLO07222.1 - 0.11 12.7 0.0 0.28 11.4 0.0 1.6 1 0 0 1 1 1 0 Chlamydia cysteine-rich outer membrane protein 6 G0-G1_switch_2 PF15103.1 KLO07224.1 - 0.74 10.0 7.7 6 7.1 0.0 3.3 3 0 0 3 3 3 0 G0/G1 switch protein 2 BTB PF00651.26 KLO07225.1 - 0.00068 19.6 0.3 0.0017 18.3 0.2 1.5 1 1 0 1 1 1 1 BTB/POZ domain BTB PF00651.26 KLO07226.1 - 1.9e-08 34.2 0.1 4.7e-08 33.0 0.0 1.6 1 1 0 1 1 1 1 BTB/POZ domain Oxidored_FMN PF00724.15 KLO07227.1 - 6e-92 308.2 0.0 7e-92 308.0 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Lipase_3 PF01764.20 KLO07228.1 - 1.1e-15 57.4 0.0 1.6e-15 56.9 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.2 KLO07228.1 - 0.061 13.1 0.0 0.082 12.7 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family BTB PF00651.26 KLO07229.1 - 0.00039 20.3 0.0 0.00078 19.4 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain APH PF01636.18 KLO07231.1 - 1.1e-06 28.5 0.0 1.8e-06 27.8 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family F-box-like PF12937.2 KLO07235.1 - 1.2e-06 28.1 0.2 3.2e-06 26.7 0.2 1.8 1 0 0 1 1 1 1 F-box-like Fungal_trans PF04082.13 KLO07236.1 - 3.2e-19 68.8 2.1 5e-19 68.1 1.5 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KLO07236.1 - 3.3e-06 26.8 12.0 5.8e-06 26.1 8.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Laminin_N PF00055.12 KLO07237.1 - 0.069 12.1 1.0 0.35 9.8 0.7 2.0 1 1 0 1 1 1 0 Laminin N-terminal (Domain VI) Abhydrolase_3 PF07859.8 KLO07238.1 - 2.6e-15 56.5 0.0 5.1e-15 55.6 0.0 1.5 2 0 0 2 2 2 1 alpha/beta hydrolase fold Chlorophyllase2 PF12740.2 KLO07238.1 - 2.2e-08 33.3 0.0 3.3e-08 32.7 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase enzyme Abhydrolase_6 PF12697.2 KLO07238.1 - 5.6e-08 32.9 0.2 8.3e-08 32.3 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KLO07238.1 - 1.6e-07 31.1 0.0 2.4e-07 30.6 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 KLO07238.1 - 0.0025 17.0 0.0 0.64 9.1 0.0 2.4 2 0 0 2 2 2 2 Prolyl oligopeptidase family Chlorophyllase PF07224.6 KLO07238.1 - 0.0034 16.2 0.0 0.0052 15.6 0.0 1.3 1 0 0 1 1 1 1 Chlorophyllase COesterase PF00135.23 KLO07238.1 - 0.0074 15.0 0.0 0.051 12.2 0.0 1.9 2 0 0 2 2 2 1 Carboxylesterase family Esterase PF00756.15 KLO07238.1 - 0.083 12.2 0.0 0.15 11.4 0.0 1.4 1 0 0 1 1 1 0 Putative esterase CNH PF00780.17 KLO07239.1 - 6.4e-78 261.9 0.0 1.2e-77 261.0 0.0 1.4 1 0 0 1 1 1 1 CNH domain PH_5 PF15405.1 KLO07239.1 - 4.7e-45 152.8 0.1 9.3e-45 151.8 0.0 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain RhoGEF PF00621.15 KLO07239.1 - 7e-36 123.7 0.0 1.1e-35 123.1 0.0 1.3 1 0 0 1 1 1 1 RhoGEF domain DEP PF00610.16 KLO07239.1 - 1.9e-13 49.9 0.2 6.5e-13 48.2 0.0 2.1 2 0 0 2 2 2 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) DUF2442 PF10387.4 KLO07239.1 - 0.021 14.8 0.0 0.065 13.2 0.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF2442) PH_10 PF15411.1 KLO07239.1 - 0.055 13.6 0.0 0.18 11.9 0.0 1.9 1 0 0 1 1 1 0 Pleckstrin homology domain Transaldolase PF00923.14 KLO07240.1 - 3.7e-09 36.1 0.0 6.4e-09 35.3 0.0 1.4 1 0 0 1 1 1 1 Transaldolase WD40 PF00400.27 KLO07241.1 - 3.2e-42 140.9 21.6 4.5e-09 35.8 0.5 7.8 7 0 0 7 7 7 6 WD domain, G-beta repeat NACHT PF05729.7 KLO07241.1 - 1.6e-13 50.6 0.6 3.9e-05 23.3 0.0 3.4 2 2 0 2 2 2 2 NACHT domain AAA_16 PF13191.1 KLO07241.1 - 2.6e-12 47.1 0.8 1.8e-06 28.0 0.0 3.5 3 1 0 3 3 3 2 AAA ATPase domain AAA_22 PF13401.1 KLO07241.1 - 6.4e-10 39.2 0.0 0.0019 18.3 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_17 PF13207.1 KLO07241.1 - 6.8e-08 33.3 0.1 0.015 16.0 0.0 3.7 2 1 0 2 2 2 2 AAA domain AAA PF00004.24 KLO07241.1 - 9.8e-08 32.2 0.0 0.0022 18.2 0.0 3.1 2 1 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.1 KLO07241.1 - 1.5e-06 28.1 0.0 0.016 15.0 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.1 KLO07241.1 - 1.2e-05 24.8 0.0 0.17 11.2 0.0 3.4 3 0 0 3 3 3 2 AAA domain Zeta_toxin PF06414.7 KLO07241.1 - 1.3e-05 24.3 0.0 0.062 12.3 0.0 2.3 2 0 0 2 2 2 2 Zeta toxin APS_kinase PF01583.15 KLO07241.1 - 2.4e-05 24.0 0.0 0.006 16.2 0.0 2.5 2 0 0 2 2 2 1 Adenylylsulphate kinase NB-ARC PF00931.17 KLO07241.1 - 2.8e-05 23.1 0.0 0.046 12.5 0.0 2.4 2 0 0 2 2 2 2 NB-ARC domain AAA_18 PF13238.1 KLO07241.1 - 2.8e-05 24.4 0.0 0.041 14.1 0.0 3.1 3 0 0 3 3 2 1 AAA domain RNA_helicase PF00910.17 KLO07241.1 - 3.3e-05 23.9 0.0 0.49 10.6 0.0 2.9 2 0 0 2 2 2 2 RNA helicase AAA_19 PF13245.1 KLO07241.1 - 7.2e-05 22.4 0.0 0.054 13.2 0.0 3.0 3 0 0 3 3 2 1 Part of AAA domain AAA_5 PF07728.9 KLO07241.1 - 0.00052 19.7 0.0 0.034 13.8 0.0 2.9 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.12 KLO07241.1 - 0.00064 19.1 0.0 0.28 10.6 0.0 2.5 2 0 0 2 2 2 1 IstB-like ATP binding protein FtsK_SpoIIIE PF01580.13 KLO07241.1 - 0.00067 19.1 0.0 0.38 10.1 0.0 2.6 2 0 0 2 2 2 1 FtsK/SpoIIIE family Viral_helicase1 PF01443.13 KLO07241.1 - 0.0012 18.4 0.0 0.12 11.9 0.0 2.4 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase PPV_E1_C PF00519.12 KLO07241.1 - 0.0025 16.4 0.0 0.21 10.1 0.0 2.2 2 0 0 2 2 2 1 Papillomavirus helicase ArgK PF03308.11 KLO07241.1 - 0.0038 16.0 0.0 0.32 9.7 0.0 2.2 2 0 0 2 2 2 1 ArgK protein AAA_10 PF12846.2 KLO07241.1 - 0.004 16.6 0.0 1.1 8.6 0.0 2.4 2 0 0 2 2 2 1 AAA-like domain Parvo_NS1 PF01057.12 KLO07241.1 - 0.0046 15.8 0.0 0.065 12.0 0.0 2.1 2 0 0 2 2 2 1 Parvovirus non-structural protein NS1 ABC_tran PF00005.22 KLO07241.1 - 0.0052 17.0 0.0 1.2 9.4 0.0 2.6 2 0 0 2 2 2 1 ABC transporter KAP_NTPase PF07693.9 KLO07241.1 - 0.0065 15.5 3.9 0.068 12.1 0.1 2.9 2 1 0 3 3 3 1 KAP family P-loop domain MobB PF03205.9 KLO07241.1 - 0.0072 16.0 0.0 0.27 10.9 0.0 2.4 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_14 PF13173.1 KLO07241.1 - 0.0081 16.0 0.0 4 7.3 0.0 3.4 2 1 0 2 2 2 0 AAA domain AAA_30 PF13604.1 KLO07241.1 - 0.01 15.3 0.0 0.35 10.4 0.0 2.3 2 0 0 2 2 2 0 AAA domain DUF2075 PF09848.4 KLO07241.1 - 0.012 14.6 0.0 1.3 7.8 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) IL3 PF02059.10 KLO07241.1 - 0.014 15.3 0.0 0.49 10.3 0.0 2.9 3 0 0 3 3 3 0 Interleukin-3 Torsin PF06309.6 KLO07241.1 - 0.02 14.7 0.0 1.6 8.6 0.0 2.5 2 0 0 2 2 2 0 Torsin Miro PF08477.8 KLO07241.1 - 0.029 14.8 0.0 0.46 10.9 0.0 2.6 2 0 0 2 2 2 0 Miro-like protein AAA_29 PF13555.1 KLO07241.1 - 0.036 13.5 0.0 1.8 8.1 0.0 2.4 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_PrkA PF08298.6 KLO07241.1 - 0.092 11.4 0.0 1.1 7.8 0.0 2.2 2 0 0 2 2 2 0 PrkA AAA domain MMR_HSR1 PF01926.18 KLO07241.1 - 0.1 12.5 0.0 24 4.9 0.0 2.6 2 0 0 2 2 2 0 50S ribosome-binding GTPase Zot PF05707.7 KLO07241.1 - 0.19 11.1 0.0 1.5 8.2 0.0 2.2 2 0 0 2 2 2 0 Zonular occludens toxin (Zot) KTI12 PF08433.5 KLO07241.1 - 0.19 10.8 0.0 4.1 6.5 0.0 2.2 2 0 0 2 2 2 0 Chromatin associated protein KTI12 ADK PF00406.17 KLO07241.1 - 0.27 11.1 0.2 17 5.2 0.0 2.5 2 0 0 2 2 2 0 Adenylate kinase Mg_chelatase PF01078.16 KLO07241.1 - 0.27 10.3 0.0 16 4.5 0.0 2.5 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI DUF258 PF03193.11 KLO07241.1 - 0.34 10.0 0.0 16 4.6 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function, DUF258 ATP_bind_1 PF03029.12 KLO07241.1 - 0.35 10.3 0.5 12 5.3 0.0 2.7 3 0 0 3 3 2 0 Conserved hypothetical ATP binding protein NTPase_1 PF03266.10 KLO07241.1 - 0.44 10.2 0.0 1.8 8.2 0.0 2.1 2 0 0 2 2 1 0 NTPase Chibby PF14645.1 KLO07242.1 - 0.047 13.5 0.1 0.072 12.9 0.0 1.2 1 0 0 1 1 1 0 Chibby family DUF2567 PF10821.3 KLO07243.1 - 0.001 18.6 1.6 0.0059 16.1 0.1 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF2567) DUF4448 PF14610.1 KLO07243.1 - 0.031 13.7 0.0 0.041 13.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) Rifin_STEVOR PF02009.11 KLO07243.1 - 0.3 10.6 0.6 0.51 9.9 0.4 1.3 1 0 0 1 1 1 0 Rifin/stevor family Hexapep PF00132.19 KLO07244.1 - 2.2e-13 49.0 18.6 1.7e-07 30.3 0.5 4.4 3 1 1 4 4 4 3 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.1 KLO07244.1 - 7e-07 28.6 15.4 5e-05 22.7 2.0 3.7 3 1 1 4 4 4 3 Hexapeptide repeat of succinyl-transferase Fucokinase PF07959.7 KLO07244.1 - 0.0004 19.0 0.0 0.00051 18.7 0.0 1.2 1 0 0 1 1 1 1 L-fucokinase GCV_T PF01571.16 KLO07245.1 - 1.3e-65 220.7 0.0 1.6e-65 220.4 0.0 1.1 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain GCV_T_C PF08669.6 KLO07245.1 - 2.1e-25 88.5 0.1 3.8e-25 87.7 0.0 1.5 1 0 0 1 1 1 1 Glycine cleavage T-protein C-terminal barrel domain SoxG PF04268.7 KLO07245.1 - 0.024 14.4 0.0 0.13 12.1 0.0 2.1 2 0 0 2 2 2 0 Sarcosine oxidase, gamma subunit family EntA_Immun PF08951.5 KLO07246.1 - 0.13 12.4 0.1 0.28 11.3 0.0 1.6 1 0 0 1 1 1 0 Enterocin A Immunity MFS_1 PF07690.11 KLO07248.1 - 1.4e-41 142.3 22.9 1.4e-41 142.3 15.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KLO07248.1 - 2.7e-18 65.7 8.6 2.7e-18 65.7 6.0 1.9 2 0 0 2 2 2 1 Sugar (and other) transporter Erythro-docking PF09277.6 KLO07254.1 - 0.02 14.5 0.1 0.063 12.9 0.1 1.8 1 0 0 1 1 1 0 Erythronolide synthase, docking F-box-like PF12937.2 KLO07257.1 - 8.7e-05 22.1 0.2 0.00058 19.5 0.1 2.5 2 0 0 2 2 2 1 F-box-like F-box-like PF12937.2 KLO07258.1 - 0.0025 17.5 0.2 0.013 15.2 0.0 2.4 2 0 0 2 2 2 1 F-box-like Nop14 PF04147.7 KLO07258.1 - 0.09 10.6 10.5 0.13 10.1 7.3 1.1 1 0 0 1 1 1 0 Nop14-like family G3P_antiterm PF04309.7 KLO07258.1 - 0.1 11.6 0.0 0.19 10.7 0.0 1.4 1 0 0 1 1 1 0 Glycerol-3-phosphate responsive antiterminator Sigma70_ner PF04546.8 KLO07258.1 - 2.7 7.5 9.4 4.9 6.7 6.5 1.4 1 0 0 1 1 1 0 Sigma-70, non-essential region CDC45 PF02724.9 KLO07258.1 - 3.6 5.5 8.6 5.1 4.9 6.0 1.1 1 0 0 1 1 1 0 CDC45-like protein SDA1 PF05285.7 KLO07258.1 - 7.5 5.7 12.2 11 5.1 8.5 1.1 1 0 0 1 1 1 0 SDA1 F-box-like PF12937.2 KLO07259.1 - 7.4e-06 25.5 0.1 3.5e-05 23.4 0.0 2.3 1 1 0 1 1 1 1 F-box-like F-box PF00646.28 KLO07259.1 - 0.0028 17.2 2.5 8.4 6.1 0.0 3.8 3 0 0 3 3 3 2 F-box domain Metallophos PF00149.23 KLO07261.1 - 1.7e-10 40.6 2.4 3.8e-10 39.4 1.7 1.7 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 KLO07261.1 - 0.0021 17.9 0.0 0.011 15.5 0.0 2.1 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Wbp11 PF09429.5 KLO07262.1 - 3.1e-20 71.9 11.3 6.3e-20 70.9 7.9 1.6 1 0 0 1 1 1 1 WW domain binding protein 11 NpwBP PF12622.2 KLO07262.1 - 2.9e-17 62.8 4.4 2.9e-17 62.8 3.0 5.8 5 1 1 6 6 6 1 mRNA biogenesis factor TMF_TATA_bd PF12325.3 KLO07262.1 - 0.86 9.3 8.3 1.5 8.5 5.8 1.3 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding Fzo_mitofusin PF04799.8 KLO07262.1 - 0.91 8.8 2.4 1.4 8.2 1.7 1.2 1 0 0 1 1 1 0 fzo-like conserved region F-box-like PF12937.2 KLO07263.1 - 4.6e-06 26.2 0.3 1.8e-05 24.3 0.2 2.1 1 1 0 1 1 1 1 F-box-like F-box PF00646.28 KLO07263.1 - 0.035 13.7 0.6 19 5.0 0.0 3.3 3 0 0 3 3 3 0 F-box domain F-box-like PF12937.2 KLO07264.1 - 2.6e-07 30.2 0.2 6.8e-07 28.9 0.1 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KLO07264.1 - 0.016 14.8 1.2 5.4 6.7 0.2 2.9 2 0 0 2 2 2 0 F-box domain F-box-like PF12937.2 KLO07265.1 - 5.5e-05 22.8 0.0 0.00017 21.2 0.0 1.9 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 KLO07265.1 - 0.13 11.9 2.2 51 3.6 0.0 3.8 4 0 0 4 4 4 0 F-box domain LRR_8 PF13855.1 KLO07265.1 - 0.16 11.7 2.0 2.3 8.0 0.1 3.5 4 0 0 4 4 4 0 Leucine rich repeat F-box-like PF12937.2 KLO07266.1 - 8.8e-07 28.5 0.1 3.7e-06 26.5 0.0 2.2 2 0 0 2 2 2 1 F-box-like F-box-like PF12937.2 KLO07267.1 - 1.8e-07 30.7 2.9 2e-07 30.6 0.3 2.3 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 KLO07267.1 - 0.0026 17.3 1.8 10 5.8 0.2 3.9 2 1 1 3 3 3 3 F-box domain F-box-like PF12937.2 KLO07268.1 - 2.6e-05 23.8 0.0 7.2e-05 22.4 0.0 1.9 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.2 KLO07268.1 - 9.9 5.9 9.3 4.7 6.9 0.4 3.9 4 1 0 4 4 4 0 Leucine Rich repeats (2 copies) F-box-like PF12937.2 KLO07269.1 - 1.1e-06 28.2 1.3 3.5e-06 26.6 0.1 2.6 3 1 0 3 3 3 1 F-box-like F-box PF00646.28 KLO07269.1 - 0.049 13.2 0.5 4.4 7.0 0.1 3.0 2 0 0 2 2 2 0 F-box domain LRR_8 PF13855.1 KLO07270.1 - 0.13 11.9 0.1 32 4.3 0.0 3.3 3 0 0 3 3 3 0 Leucine rich repeat F-box-like PF12937.2 KLO07271.1 - 2.5e-07 30.3 0.1 6.6e-07 28.9 0.0 1.8 1 0 0 1 1 1 1 F-box-like LRR_8 PF13855.1 KLO07274.1 - 0.0037 17.0 5.5 20 5.0 1.3 4.8 4 2 0 4 4 4 2 Leucine rich repeat LRR_4 PF12799.2 KLO07274.1 - 0.052 13.1 3.5 25 4.6 0.0 4.6 5 0 0 5 5 5 0 Leucine Rich repeats (2 copies) LRR_6 PF13516.1 KLO07274.1 - 2.5 8.4 4.5 1.1e+02 3.3 0.1 4.4 4 0 0 4 4 4 0 Leucine Rich repeat F-box-like PF12937.2 KLO07275.1 - 0.0035 17.0 0.2 0.0098 15.5 0.1 1.8 1 0 0 1 1 1 1 F-box-like LRR_8 PF13855.1 KLO07275.1 - 0.011 15.4 3.5 5.5 6.8 0.0 4.2 4 1 1 5 5 5 0 Leucine rich repeat Polysacc_deac_1 PF01522.16 KLO07277.1 - 1.2e-31 108.9 0.0 2.9e-31 107.6 0.0 1.7 1 0 0 1 1 1 1 Polysaccharide deacetylase Polysacc_deac_1 PF01522.16 KLO07278.1 - 8.7e-30 102.8 0.0 1.5e-29 102.1 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide deacetylase Myticin-prepro PF10690.4 KLO07281.1 - 0.04 13.9 3.0 0.048 13.6 0.1 2.2 2 0 0 2 2 2 0 Myticin pre-proprotein from the mussel LCM PF04072.9 KLO07282.1 - 0.054 13.0 0.0 0.083 12.4 0.0 1.2 1 0 0 1 1 1 0 Leucine carboxyl methyltransferase DUF566 PF04484.7 KLO07283.1 - 0.42 10.0 10.5 0.47 9.9 7.2 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF566) DUF605 PF04652.11 KLO07283.1 - 0.47 9.7 4.9 0.48 9.7 3.4 1.1 1 0 0 1 1 1 0 Vta1 like Spt5-NGN PF03439.8 KLO07286.1 - 6.4e-10 38.6 0.0 1.6e-09 37.3 0.0 1.7 1 0 0 1 1 1 1 Early transcription elongation factor of RNA pol II, NGN section KOW PF00467.24 KLO07286.1 - 2.1e-05 24.0 16.9 0.22 11.3 0.1 4.5 4 0 0 4 4 4 3 KOW motif DUF563 PF04577.9 KLO07291.1 - 6.6e-20 71.9 0.0 1.2e-19 71.0 0.0 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF563) Hexapep PF00132.19 KLO07292.1 - 1.1e-13 50.0 17.7 1.7e-07 30.3 0.5 4.3 3 1 1 4 4 4 3 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.1 KLO07292.1 - 6.7e-07 28.7 15.3 5e-05 22.7 2.0 3.7 3 1 1 4 4 4 3 Hexapeptide repeat of succinyl-transferase Fucokinase PF07959.7 KLO07292.1 - 0.00039 19.1 0.0 0.00051 18.7 0.0 1.2 1 0 0 1 1 1 1 L-fucokinase DUF3678 PF12435.3 KLO07294.1 - 0.13 11.8 4.3 0.26 10.8 0.5 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3678) DUF1510 PF07423.6 KLO07294.1 - 0.33 10.2 4.7 0.58 9.4 3.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Pkinase PF00069.20 KLO07299.1 - 3.4e-45 154.2 0.0 5.1e-45 153.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KLO07299.1 - 2.7e-41 141.3 0.0 3.7e-41 140.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KLO07299.1 - 6.7e-05 21.9 0.0 0.00011 21.2 0.0 1.3 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.17 KLO07299.1 - 0.008 15.5 0.1 0.088 12.1 0.0 2.1 2 0 0 2 2 2 1 RIO1 family Ycf66_N PF07444.6 KLO07300.1 - 0.18 11.5 7.9 0.76 9.5 1.3 3.2 3 1 0 3 3 3 0 Ycf66 protein N-terminus DUF1625 PF07787.7 KLO07301.1 - 0.93 8.6 3.7 2.5 7.2 2.6 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1625) Xan_ur_permease PF00860.15 KLO07302.1 - 3.8e-30 104.6 22.6 4.5e-29 101.1 14.8 2.4 2 1 0 2 2 2 1 Permease family DASH_Spc19 PF08287.6 KLO07304.1 - 0.034 13.7 0.0 0.047 13.3 0.0 1.1 1 0 0 1 1 1 0 Spc19 MADF_DNA_bdg PF10545.4 KLO07304.1 - 0.045 13.9 0.2 0.079 13.1 0.1 1.4 1 0 0 1 1 1 0 Alcohol dehydrogenase transcription factor Myb/SANT-like Complex1_LYR PF05347.10 KLO07304.1 - 0.067 13.0 2.2 3.3 7.5 0.3 2.5 1 1 1 2 2 2 0 Complex 1 protein (LYR family) PPR_2 PF13041.1 KLO07306.1 - 0.11 12.4 0.0 0.23 11.4 0.0 1.5 1 0 0 1 1 1 0 PPR repeat family His_kinase PF06580.8 KLO07309.1 - 0.047 13.6 0.5 3 7.8 0.0 2.6 2 0 0 2 2 2 0 Histidine kinase Adaptin_N PF01602.15 KLO07309.1 - 0.099 10.9 0.5 0.16 10.2 0.3 1.2 1 0 0 1 1 1 0 Adaptin N terminal region F-box-like PF12937.2 KLO07312.1 - 1.3e-06 28.0 4.4 9.3e-06 25.2 3.1 2.4 1 1 0 1 1 1 1 F-box-like LRR_7 PF13504.1 KLO07312.1 - 0.25 11.7 1.0 56 4.6 0.0 4.0 4 0 0 4 4 4 0 Leucine rich repeat APH PF01636.18 KLO07313.1 - 3.5e-07 30.1 2.8 0.011 15.4 0.1 3.5 4 0 0 4 4 4 2 Phosphotransferase enzyme family VWA_3 PF13768.1 KLO07314.1 - 1.7e-23 83.0 0.0 3.7e-23 81.9 0.0 1.6 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.1 KLO07314.1 - 1.1e-18 67.9 0.0 3.4e-18 66.3 0.0 1.9 2 0 0 2 2 2 1 von Willebrand factor type A domain VIT PF08487.5 KLO07314.1 - 1.5e-16 60.1 0.0 3e-16 59.1 0.0 1.4 1 0 0 1 1 1 1 Vault protein inter-alpha-trypsin domain VWA PF00092.23 KLO07314.1 - 2.1e-12 47.1 0.0 4.7e-12 45.9 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_CoxE PF05762.9 KLO07314.1 - 9.4e-06 24.9 0.0 2.1e-05 23.8 0.0 1.5 1 0 0 1 1 1 1 VWA domain containing CoxE-like protein VIT_2 PF13757.1 KLO07314.1 - 2.9e-05 23.4 0.0 6.7e-05 22.2 0.0 1.5 1 0 0 1 1 1 1 Vault protein inter-alpha-trypsin domain vWA-TerF-like PF10138.4 KLO07314.1 - 0.0071 16.1 0.0 0.013 15.3 0.0 1.3 1 0 0 1 1 1 1 vWA found in TerF C terminus Pkinase_Tyr PF07714.12 KLO07315.1 - 0.006 15.6 0.0 0.011 14.8 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 KLO07315.1 - 0.014 14.5 0.0 0.023 13.8 0.0 1.3 1 0 0 1 1 1 0 Protein kinase domain Mesothelin PF06060.7 KLO07315.1 - 0.029 12.4 0.0 0.044 11.8 0.0 1.1 1 0 0 1 1 1 0 Pre-pro-megakaryocyte potentiating factor precursor (Mesothelin) Pkinase PF00069.20 KLO07316.1 - 2.3e-44 151.4 0.0 3.8e-35 121.2 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 KLO07316.1 - 9.2e-41 139.6 0.0 2.5e-33 115.2 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 KLO07316.1 - 9.6e-08 31.3 0.0 8.3e-07 28.2 0.0 2.0 2 0 0 2 2 2 1 Kinase-like Choline_kinase PF01633.15 KLO07316.1 - 0.13 11.7 0.0 0.25 10.8 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase APH PF01636.18 KLO07316.1 - 0.15 11.7 0.0 0.29 10.8 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Cation_efflux PF01545.16 KLO07318.1 - 2.1e-28 99.1 6.1 2.6e-28 98.9 4.2 1.1 1 0 0 1 1 1 1 Cation efflux family DUF2077 PF09850.4 KLO07318.1 - 0.15 11.4 0.7 0.93 8.8 0.1 2.2 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2077) DPBB_1 PF03330.13 KLO07319.1 - 4.6e-08 32.9 0.2 7.9e-08 32.1 0.1 1.5 1 1 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Cerato-platanin PF07249.7 KLO07319.1 - 0.081 12.9 0.0 0.093 12.7 0.0 1.2 1 0 0 1 1 1 0 Cerato-platanin Acetyltransf_7 PF13508.1 KLO07321.1 - 0.029 14.5 0.0 0.046 13.8 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Ustilago_mating PF05722.7 KLO07323.1 - 0.074 12.3 0.5 0.11 11.7 0.3 1.2 1 0 0 1 1 1 0 Ustilago B locus mating-type protein F-box-like PF12937.2 KLO07324.1 - 2.5e-07 30.3 0.4 8.6e-07 28.5 0.3 2.0 1 0 0 1 1 1 1 F-box-like zf-C4H2 PF10146.4 KLO07325.1 - 8.9e-07 29.1 1.8 8.9e-07 29.1 1.3 2.0 2 0 0 2 2 2 1 Zinc finger-containing protein Myosin_tail_1 PF01576.14 KLO07325.1 - 0.0021 15.9 8.9 0.0025 15.6 6.2 1.0 1 0 0 1 1 1 1 Myosin tail IncA PF04156.9 KLO07325.1 - 0.0033 17.0 2.9 0.0039 16.8 2.0 1.1 1 0 0 1 1 1 1 IncA protein APG6 PF04111.7 KLO07325.1 - 0.094 11.7 6.5 0.13 11.3 4.5 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 Metal_resist PF13801.1 KLO07325.1 - 0.097 12.6 2.2 0.23 11.4 1.5 1.6 1 0 0 1 1 1 0 Heavy-metal resistance AT_hook PF02178.14 KLO07325.1 - 1.4 8.8 8.1 3.4 7.6 5.6 1.7 1 0 0 1 1 1 0 AT hook motif F-box-like PF12937.2 KLO07326.1 - 6.8e-07 28.9 2.0 2.4e-06 27.1 1.4 2.0 1 1 0 1 1 1 1 F-box-like LRR_4 PF12799.2 KLO07326.1 - 0.49 10.0 5.4 80 3.0 0.0 4.3 3 1 1 4 4 4 0 Leucine Rich repeats (2 copies) PLDc_2 PF13091.1 KLO07327.1 - 4.3e-09 36.1 0.0 0.0019 17.9 0.0 2.3 2 0 0 2 2 2 2 PLD-like domain PLDc PF00614.17 KLO07327.1 - 8.5e-09 34.9 0.1 0.00066 19.3 0.1 2.7 2 0 0 2 2 2 2 Phospholipase D Active site motif zf-C3HC4_3 PF13920.1 KLO07328.1 - 8.9e-10 38.0 16.2 8.9e-10 38.0 11.2 1.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KLO07328.1 - 0.12 12.4 23.8 0.2 11.7 13.3 2.4 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-MYND PF01753.13 KLO07329.1 - 4.4e-08 32.8 13.8 7.1e-08 32.2 9.6 1.3 1 0 0 1 1 1 1 MYND finger DUF1035 PF06281.7 KLO07329.1 - 0.13 12.0 0.0 2.9 7.7 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1035) zf-Mss51 PF13824.1 KLO07329.1 - 0.19 11.6 6.2 0.37 10.6 4.3 1.5 1 0 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 PWWP PF00855.12 KLO07330.1 - 0.5 10.5 3.1 31 4.8 0.0 3.1 2 1 0 2 2 2 0 PWWP domain GDA1_CD39 PF01150.12 KLO07331.1 - 3.6e-108 361.8 0.0 5.3e-101 338.2 0.0 2.1 2 0 0 2 2 2 2 GDA1/CD39 (nucleoside phosphatase) family Ppx-GppA PF02541.11 KLO07331.1 - 0.032 13.4 0.0 0.054 12.6 0.0 1.2 1 0 0 1 1 1 0 Ppx/GppA phosphatase family DUF2636 PF11120.3 KLO07331.1 - 0.92 9.0 4.7 0.16 11.5 0.4 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2636) Fungal_trans PF04082.13 KLO07333.1 - 5.3e-18 64.8 0.3 9.6e-18 63.9 0.2 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KLO07333.1 - 7.4e-05 22.5 9.2 0.00017 21.4 6.3 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HTH_29 PF13551.1 KLO07333.1 - 0.004 17.2 0.1 0.012 15.7 0.0 1.8 1 0 0 1 1 1 1 Winged helix-turn helix DUF3760 PF12586.3 KLO07334.1 - 0.23 11.2 1.5 0.85 9.5 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3760) zf-C2H2 PF00096.21 KLO07335.1 - 7.1e-06 26.0 1.1 0.049 13.9 0.0 2.4 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.3 KLO07335.1 - 3.1e-05 23.9 0.5 0.11 12.7 0.1 2.4 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.1 KLO07335.1 - 0.00036 20.6 2.2 0.071 13.4 0.0 2.4 2 0 0 2 2 2 2 C2H2-type zinc finger zf-Di19 PF05605.7 KLO07335.1 - 0.056 13.5 1.4 1.1 9.4 1.0 2.1 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding PAT1 PF09770.4 KLO07335.1 - 0.07 11.3 21.7 0.095 10.9 15.0 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 zf-C2H2_2 PF12756.2 KLO07335.1 - 0.17 12.0 1.2 1.9 8.6 0.9 2.0 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) WD40 PF00400.27 KLO07336.1 - 2.2e-58 192.1 25.1 8.3e-11 41.3 0.3 7.6 7 0 0 7 7 7 7 WD domain, G-beta repeat F-box-like PF12937.2 KLO07336.1 - 1.9e-11 43.4 0.4 1.9e-11 43.4 0.3 2.4 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 KLO07336.1 - 3.7e-10 39.1 2.6 5.1e-10 38.7 0.3 2.2 2 0 0 2 2 2 1 F-box domain Nup160 PF11715.3 KLO07336.1 - 7.4e-09 34.2 1.0 0.012 13.7 0.1 5.6 4 2 1 5 5 5 4 Nucleoporin Nup120/160 PQQ_2 PF13360.1 KLO07336.1 - 0.0066 15.9 2.4 0.72 9.2 0.1 3.4 2 2 1 3 3 3 2 PQQ-like domain Nucleoporin_N PF08801.6 KLO07336.1 - 0.022 13.5 0.2 7.8 5.1 0.0 3.9 3 2 2 5 5 5 0 Nup133 N terminal like Nop14 PF04147.7 KLO07336.1 - 2.7 5.8 5.8 4.6 5.0 4.0 1.3 1 0 0 1 1 1 0 Nop14-like family Pro_isomerase PF00160.16 KLO07337.1 - 3.1e-51 173.6 0.1 3.4e-51 173.4 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Tim54 PF11711.3 KLO07338.1 - 3.6e-72 243.0 0.2 1.3e-71 241.2 0.1 1.8 1 1 0 1 1 1 1 Inner membrane protein import complex subunit Tim54 Sec63 PF02889.11 KLO07339.1 - 3.1e-45 154.7 0.0 7.2e-45 153.5 0.0 1.6 1 1 0 1 1 1 1 Sec63 Brl domain DEAD PF00270.24 KLO07339.1 - 6e-24 84.4 0.0 2.4e-23 82.4 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KLO07339.1 - 1.3e-09 37.8 0.0 2.9e-09 36.6 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 KLO07339.1 - 2.5e-08 33.9 0.0 7e-08 32.5 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit HHH_5 PF14520.1 KLO07339.1 - 0.0046 17.0 0.1 0.022 14.9 0.0 2.1 2 0 0 2 2 2 1 Helix-hairpin-helix domain AAA_10 PF12846.2 KLO07339.1 - 0.062 12.7 0.1 0.87 8.9 0.0 2.3 1 1 0 2 2 2 0 AAA-like domain AAA_22 PF13401.1 KLO07339.1 - 0.074 13.1 0.1 0.32 11.1 0.0 2.1 1 1 0 1 1 1 0 AAA domain Cdd1 PF11731.3 KLO07339.1 - 0.12 12.3 0.0 0.32 10.9 0.0 1.7 1 0 0 1 1 1 0 Pathogenicity locus Tyr_Deacylase PF02580.11 KLO07340.1 - 6.6e-38 129.9 0.0 7.7e-38 129.7 0.0 1.0 1 0 0 1 1 1 1 D-Tyr-tRNA(Tyr) deacylase DUF2848 PF11010.3 KLO07340.1 - 0.083 12.3 0.0 0.14 11.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2848) AIRC PF00731.15 KLO07341.1 - 1.1e-64 216.1 1.1 2.5e-64 215.1 0.8 1.6 1 0 0 1 1 1 1 AIR carboxylase ATP-grasp PF02222.17 KLO07341.1 - 1.4e-57 193.8 0.0 2.4e-57 193.0 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_4 PF13535.1 KLO07341.1 - 1.5e-11 44.3 0.0 3.1e-11 43.3 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain ATPgrasp_Ter PF15632.1 KLO07341.1 - 0.0058 15.4 0.0 0.17 10.6 0.0 2.2 2 0 0 2 2 2 1 ATP-grasp in the biosynthetic pathway with Ter operon CPSase_L_D2 PF02786.12 KLO07341.1 - 0.0063 15.8 0.0 0.014 14.6 0.0 1.8 1 1 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain 2-Hacid_dh_C PF02826.14 KLO07341.1 - 0.012 14.7 0.1 0.026 13.6 0.0 1.6 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Dala_Dala_lig_C PF07478.8 KLO07341.1 - 0.024 14.0 0.0 0.94 8.8 0.0 2.4 2 0 0 2 2 2 0 D-ala D-ala ligase C-terminus 3HCDH_N PF02737.13 KLO07341.1 - 0.054 13.1 0.2 0.14 11.7 0.1 1.8 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain XdhC_C PF13478.1 KLO07341.1 - 0.061 13.6 0.1 0.21 11.8 0.0 1.9 2 0 0 2 2 2 0 XdhC Rossmann domain CoA_binding_2 PF13380.1 KLO07341.1 - 0.061 13.4 0.3 16 5.6 0.0 2.9 2 1 1 3 3 3 0 CoA binding domain ATP-grasp_3 PF02655.9 KLO07341.1 - 0.11 12.3 0.0 0.28 11.0 0.0 1.7 1 0 0 1 1 1 0 ATP-grasp domain F420_oxidored PF03807.12 KLO07341.1 - 0.11 12.9 1.5 1.2 9.5 0.7 2.7 2 1 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent Shikimate_DH PF01488.15 KLO07341.1 - 0.13 12.3 1.6 0.4 10.7 0.1 2.3 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase E1-E2_ATPase PF00122.15 KLO07342.1 - 1.3e-54 184.6 4.6 2.3e-54 183.8 3.2 1.4 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 KLO07342.1 - 4.4e-39 133.9 3.1 4.4e-39 133.9 2.2 3.1 3 0 0 3 3 3 2 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 KLO07342.1 - 3.9e-33 115.6 0.0 3.1e-32 112.7 0.0 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 KLO07342.1 - 1.6e-16 60.0 0.0 2.9e-16 59.2 0.0 1.4 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 KLO07342.1 - 4.9e-13 49.6 0.0 1.5e-12 48.1 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 KLO07342.1 - 1.1e-11 43.9 0.0 8.7e-11 41.1 0.0 2.4 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 KLO07342.1 - 2.5e-07 30.5 0.6 3.8e-06 26.6 0.2 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Npa1 PF11707.3 KLO07343.1 - 1.5e-68 231.2 0.1 1.4e-67 228.0 0.0 2.6 3 0 0 3 3 3 1 Ribosome 60S biogenesis N-terminal Proteasome PF00227.21 KLO07344.1 - 4.3e-32 110.9 0.0 1.2e-31 109.5 0.0 1.6 1 1 0 1 1 1 1 Proteasome subunit Uteroglobin PF01099.12 KLO07344.1 - 0.03 14.1 0.0 0.055 13.2 0.0 1.4 1 0 0 1 1 1 0 Uteroglobin family DUF4130 PF13566.1 KLO07345.1 - 0.074 12.6 0.0 0.084 12.4 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4130 DUF2890 PF11081.3 KLO07347.1 - 0.21 11.6 0.0 32 4.4 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF2890) Ldh_1_N PF00056.18 KLO07348.1 - 3e-44 150.2 0.0 4.3e-44 149.7 0.0 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.13 KLO07348.1 - 8.1e-44 149.4 0.0 1.3e-43 148.7 0.0 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain 3Beta_HSD PF01073.14 KLO07348.1 - 0.0016 17.1 0.0 0.0025 16.5 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Semialdhyde_dh PF01118.19 KLO07348.1 - 0.018 15.3 0.1 0.12 12.7 0.0 2.2 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain Glyco_hydro_4 PF02056.11 KLO07348.1 - 0.074 12.3 0.0 1.1 8.5 0.0 2.2 1 1 1 2 2 2 0 Family 4 glycosyl hydrolase Amidohydro_1 PF01979.15 KLO07349.1 - 1.4e-26 93.9 0.0 1.8e-26 93.6 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_4 PF13147.1 KLO07349.1 - 2.5e-26 93.3 3.5 1.8e-25 90.5 2.4 2.2 1 1 0 1 1 1 1 Amidohydrolase Amidohydro_5 PF13594.1 KLO07349.1 - 1.3e-12 47.2 0.1 3.6e-12 45.9 0.1 1.8 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_3 PF07969.6 KLO07349.1 - 2.4e-06 27.0 0.4 0.013 14.7 0.1 2.8 2 1 0 2 2 2 2 Amidohydrolase family Clp1 PF06807.9 KLO07350.1 - 4.3e-13 49.4 0.0 1.9e-12 47.3 0.0 1.8 1 1 0 1 1 1 1 Pre-mRNA cleavage complex II protein Clp1 MobB PF03205.9 KLO07350.1 - 1.5e-07 31.1 0.0 2.8e-07 30.3 0.0 1.3 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_16 PF13191.1 KLO07350.1 - 0.00038 20.5 0.0 0.00068 19.6 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 KLO07350.1 - 0.034 14.2 0.0 0.076 13.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.1 KLO07350.1 - 0.042 13.7 0.0 0.12 12.2 0.0 1.8 2 0 0 2 2 2 0 AAA domain Arch_ATPase PF01637.13 KLO07350.1 - 0.068 12.8 0.0 0.12 12.0 0.0 1.3 1 0 0 1 1 1 0 Archaeal ATPase Trehalose_recp PF06151.8 KLO07352.1 - 0.011 14.1 0.0 0.012 13.9 0.0 1.2 1 0 0 1 1 1 0 Trehalose receptor Retrotrans_gag PF03732.12 KLO07352.1 - 0.056 13.5 0.0 0.19 11.8 0.0 1.8 1 1 1 2 2 2 0 Retrotransposon gag protein Asp_protease_2 PF13650.1 KLO07353.1 - 0.014 15.8 0.1 0.024 15.1 0.0 1.4 1 1 0 1 1 1 0 Aspartyl protease gag-asp_proteas PF13975.1 KLO07353.1 - 0.13 12.1 0.1 0.24 11.2 0.1 1.4 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease Pet191_N PF10203.4 KLO07361.1 - 0.04 13.9 0.1 0.12 12.3 0.1 1.8 1 0 0 1 1 1 0 Cytochrome c oxidase assembly protein PET191 Toxin_40 PF15520.1 KLO07363.1 - 0.061 12.7 0.0 12 5.2 0.0 2.6 3 0 0 3 3 3 0 Putative toxin 40 DUF3035 PF11233.3 KLO07364.1 - 0.066 13.2 4.0 0.13 12.3 2.8 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3035) Acyl_transf_1 PF00698.16 KLO07365.1 - 0.017 14.4 0.0 0.019 14.2 0.0 1.1 1 0 0 1 1 1 0 Acyl transferase domain RNB PF00773.14 KLO07368.1 - 4.1e-90 302.3 0.0 5.7e-90 301.8 0.0 1.2 1 0 0 1 1 1 1 RNB domain PIN_4 PF13638.1 KLO07368.1 - 7.2e-09 35.8 0.0 1.6e-08 34.6 0.0 1.6 1 0 0 1 1 1 1 PIN domain OB_RNB PF08206.6 KLO07368.1 - 0.013 15.0 2.7 0.13 11.7 0.1 2.7 2 0 0 2 2 2 0 Ribonuclease B OB domain His_Phos_2 PF00328.17 KLO07369.1 - 9.3e-21 74.5 0.0 1.2e-20 74.2 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) DUF4064 PF13273.1 KLO07370.1 - 2.2 8.4 17.1 1.8 8.6 0.4 4.4 4 0 0 4 4 4 0 Protein of unknown function (DUF4064) Aldo_ket_red PF00248.16 KLO07372.1 - 6.3e-62 208.9 0.1 7.2e-62 208.7 0.1 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Aldo_ket_red PF00248.16 KLO07373.1 - 3.4e-64 216.4 0.1 3.9e-64 216.2 0.1 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family CGI-121 PF08617.5 KLO07373.1 - 0.078 12.6 0.1 0.17 11.5 0.1 1.4 1 0 0 1 1 1 0 Kinase binding protein CGI-121 Aldo_ket_red PF00248.16 KLO07374.1 - 5.8e-63 212.3 0.1 6.6e-63 212.1 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family F-box-like PF12937.2 KLO07375.1 - 2.5e-05 23.9 0.0 8.5e-05 22.2 0.0 1.9 1 0 0 1 1 1 1 F-box-like Spt5_N PF11942.3 KLO07376.1 - 0.0052 17.3 0.7 0.0087 16.6 0.5 1.3 1 0 0 1 1 1 1 Spt5 transcription elongation factor, acidic N-terminal UPF0564 PF10595.4 KLO07376.1 - 0.093 11.6 5.3 0.12 11.2 3.7 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0564 SRP-alpha_N PF04086.8 KLO07376.1 - 0.15 11.3 4.9 0.21 10.9 3.4 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal DUF3602 PF12223.3 KLO07377.1 - 2.1e-30 104.9 36.4 1.9e-10 40.9 3.8 5.2 1 1 5 6 6 6 6 Protein of unknown function (DUF3602) Spot_14 PF07084.7 KLO07377.1 - 0.097 12.5 0.4 2.1 8.1 0.0 2.2 2 0 0 2 2 2 0 Thyroid hormone-inducible hepatic protein Spot 14 F-box-like PF12937.2 KLO07378.1 - 0.006 16.2 0.0 0.017 14.8 0.0 1.8 1 0 0 1 1 1 1 F-box-like F-box-like PF12937.2 KLO07379.1 - 0.00019 21.0 0.0 0.00043 19.9 0.0 1.6 1 0 0 1 1 1 1 F-box-like DUF1866 PF08952.6 KLO07380.1 - 0.026 14.0 0.0 0.073 12.6 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF1866) COQ7 PF03232.8 KLO07382.1 - 1.8e-67 226.1 0.5 2e-67 225.9 0.4 1.0 1 0 0 1 1 1 1 Ubiquinone biosynthesis protein COQ7 NDUF_B4 PF07225.7 KLO07383.1 - 5e-05 23.0 0.0 5e-05 23.0 0.0 1.0 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B15 subunit (NDUFB4) G-patch PF01585.18 KLO07384.1 - 1e-13 50.8 1.5 1e-13 50.8 1.0 1.9 2 0 0 2 2 2 1 G-patch domain RRM_6 PF14259.1 KLO07384.1 - 3.7e-07 30.0 0.0 0.003 17.4 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 KLO07384.1 - 5e-06 26.0 1.8 0.019 14.5 0.0 3.5 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) G-patch_2 PF12656.2 KLO07384.1 - 7.8e-06 25.6 2.7 1.2e-05 25.0 0.5 2.4 2 0 0 2 2 2 1 DExH-box splicing factor binding site RED_N PF07808.8 KLO07384.1 - 0.0048 16.1 1.3 0.017 14.3 0.9 1.9 1 0 0 1 1 1 1 RED-like protein N-terminal region zf-C2H2_jaz PF12171.3 KLO07384.1 - 0.031 14.4 1.2 0.071 13.2 0.9 1.6 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.2 KLO07384.1 - 0.044 13.8 0.1 0.082 13.0 0.1 1.3 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) zf-C2H2 PF00096.21 KLO07384.1 - 0.078 13.3 1.0 0.19 12.1 0.7 1.7 1 0 0 1 1 1 0 Zinc finger, C2H2 type zf-C2H2_6 PF13912.1 KLO07384.1 - 1.1 9.3 3.9 0.49 10.3 0.7 1.9 2 0 0 2 2 2 0 C2H2-type zinc finger PBP PF01161.15 KLO07385.1 - 4.4e-20 72.0 0.0 6.5e-20 71.4 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein Pkinase PF00069.20 KLO07386.1 - 3.7e-63 213.0 0.0 4.4e-63 212.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KLO07386.1 - 3.1e-24 85.4 0.0 4.5e-24 84.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KLO07386.1 - 1e-05 24.6 0.0 2.2e-05 23.5 0.0 1.5 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 KLO07386.1 - 0.004 16.9 0.0 0.016 14.9 0.0 1.9 2 0 0 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 KLO07386.1 - 0.006 16.1 0.0 0.0099 15.4 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase WD40 PF00400.27 KLO07387.1 - 1.6e-60 198.9 18.9 1.3e-09 37.5 0.1 8.6 8 1 0 8 8 8 7 WD domain, G-beta repeat Nup160 PF11715.3 KLO07387.1 - 6.8e-14 50.8 12.0 0.00095 17.4 0.2 5.6 1 1 3 5 5 5 5 Nucleoporin Nup120/160 F-box-like PF12937.2 KLO07387.1 - 5.1e-11 42.1 0.0 1e-10 41.1 0.0 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KLO07387.1 - 1.9e-07 30.5 0.0 4.4e-07 29.3 0.0 1.7 1 0 0 1 1 1 1 F-box domain BBS2_Mid PF14783.1 KLO07387.1 - 0.00054 19.7 0.1 5.2 6.9 0.0 5.2 4 2 1 5 5 5 1 Ciliary BBSome complex subunit 2, middle region FH2 PF02181.18 KLO07388.1 - 2.3e-73 247.2 11.9 9.5e-73 245.1 4.3 2.3 2 0 0 2 2 2 2 Formin Homology 2 Domain Drf_GBD PF06371.8 KLO07388.1 - 2.6e-36 124.7 0.0 2.6e-36 124.7 0.0 2.6 3 0 0 3 3 3 1 Diaphanous GTPase-binding Domain Drf_FH3 PF06367.11 KLO07388.1 - 1.1e-32 113.0 1.2 3.4e-32 111.4 0.9 1.9 1 0 0 1 1 1 1 Diaphanous FH3 Domain TPR_MLP1_2 PF07926.7 KLO07388.1 - 0.014 15.1 14.4 0.91 9.2 0.0 4.2 3 2 0 3 3 3 0 TPR/MLP1/MLP2-like protein SPOUT_MTase_2 PF14419.1 KLO07388.1 - 0.04 13.0 2.7 0.037 13.2 0.3 2.0 2 0 0 2 2 2 0 AF2226-like SPOUT RNA Methylase fused to THUMP Hid1 PF12722.2 KLO07390.1 - 8.2e-155 516.8 0.0 1.8e-154 515.7 0.0 1.4 1 1 0 1 1 1 1 High-temperature-induced dauer-formation protein Dymeclin PF09742.4 KLO07390.1 - 1.1e-69 235.3 0.7 1.5e-69 234.8 0.5 1.1 1 0 0 1 1 1 1 Dyggve-Melchior-Clausen syndrome protein Copper-bind PF00127.15 KLO07391.1 - 0.00013 22.1 0.1 0.00029 21.0 0.1 1.5 1 0 0 1 1 1 1 Copper binding proteins, plastocyanin/azurin family Rad51 PF08423.6 KLO07392.1 - 1.5e-23 83.0 0.0 2.4e-23 82.3 0.0 1.2 1 0 0 1 1 1 1 Rad51 KaiC PF06745.8 KLO07392.1 - 7.4e-07 28.5 0.2 5.3e-06 25.7 0.1 2.0 1 1 0 1 1 1 1 KaiC AAA_25 PF13481.1 KLO07392.1 - 1.1e-06 28.2 0.0 3.7e-06 26.4 0.0 1.9 1 1 0 1 1 1 1 AAA domain RecA PF00154.16 KLO07392.1 - 0.0011 18.0 0.2 0.032 13.3 0.0 2.1 2 0 0 2 2 2 1 recA bacterial DNA recombination protein DnaB_C PF03796.10 KLO07392.1 - 0.0067 15.3 0.1 0.07 12.0 0.1 2.1 2 0 0 2 2 2 1 DnaB-like helicase C terminal domain Atg8 PF02991.11 KLO07393.1 - 1.8e-51 172.3 0.3 2.1e-51 172.1 0.2 1.0 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like APG12 PF04110.8 KLO07393.1 - 3.2e-08 33.6 0.0 4e-08 33.3 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 Pkinase_Tyr PF07714.12 KLO07394.1 - 2.6e-45 154.5 0.0 5e-45 153.6 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 KLO07394.1 - 4.4e-41 140.7 0.0 7.7e-41 139.9 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain RasGEF PF00617.14 KLO07394.1 - 1.1e-31 110.0 0.0 2.1e-31 109.1 0.0 1.5 1 0 0 1 1 1 1 RasGEF domain Kinase-like PF14531.1 KLO07394.1 - 0.0037 16.2 0.0 0.0065 15.4 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 KLO07394.1 - 0.0086 15.8 1.5 0.22 11.1 0.1 2.9 2 1 1 3 3 3 1 Phosphotransferase enzyme family Kdo PF06293.9 KLO07394.1 - 0.065 12.2 1.0 0.18 10.8 0.0 2.2 3 0 0 3 3 3 0 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 KLO07394.1 - 0.15 11.3 0.1 0.38 10.0 0.0 1.6 1 0 0 1 1 1 0 RIO1 family FA_hydroxylase PF04116.8 KLO07398.1 - 1e-13 51.7 20.1 1e-13 51.7 13.9 2.0 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily Methyltransf_2 PF00891.13 KLO07400.1 - 1e-31 110.0 0.0 1.7e-31 109.2 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_18 PF12847.2 KLO07400.1 - 0.00036 21.0 0.0 0.0014 19.1 0.0 2.1 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_12 PF08242.7 KLO07400.1 - 0.0065 16.9 0.0 0.018 15.4 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Dimerisation PF08100.6 KLO07400.1 - 0.015 15.0 0.0 0.041 13.7 0.0 1.7 1 0 0 1 1 1 0 Dimerisation domain CheR PF01739.13 KLO07400.1 - 0.19 10.9 0.0 0.63 9.2 0.0 1.7 2 0 0 2 2 2 0 CheR methyltransferase, SAM binding domain Corona_NS3b PF03053.9 KLO07401.1 - 0.00016 21.2 0.7 0.00027 20.5 0.5 1.3 1 0 0 1 1 1 1 ORF3b coronavirus protein FUSC_2 PF13515.1 KLO07401.1 - 3.4 7.5 11.7 0.056 13.3 1.7 2.4 1 1 0 2 2 2 0 Fusaric acid resistance protein-like Na_Ca_ex PF01699.19 KLO07404.1 - 3.6e-13 49.3 21.1 6.5e-07 29.0 3.9 3.5 2 1 1 3 3 3 2 Sodium/calcium exchanger protein Acyltransferase PF01553.16 KLO07405.1 - 4e-22 78.0 0.0 5.1e-22 77.7 0.0 1.2 1 0 0 1 1 1 1 Acyltransferase SyrA PF11089.3 KLO07405.1 - 0.1 12.4 1.6 0.2 11.5 1.1 1.4 1 0 0 1 1 1 0 Exopolysaccharide production repressor ADH_zinc_N PF00107.21 KLO07406.1 - 1.3e-16 60.3 0.0 2.1e-16 59.6 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KLO07406.1 - 1.9e-10 40.4 0.0 3.4e-10 39.6 0.0 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 KLO07406.1 - 2.3e-09 38.2 0.0 4.4e-09 37.3 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase DS PF01916.12 KLO07406.1 - 0.071 12.2 0.0 0.13 11.3 0.0 1.4 1 0 0 1 1 1 0 Deoxyhypusine synthase DUF2385 PF09539.5 KLO07407.1 - 0.13 12.6 0.0 0.28 11.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2385) PhyH PF05721.8 KLO07408.1 - 9e-16 58.5 0.1 1.4e-15 57.8 0.0 1.3 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) Calcyon PF06387.6 KLO07408.1 - 0.13 11.5 0.0 0.22 10.8 0.0 1.3 1 0 0 1 1 1 0 D1 dopamine receptor-interacting protein (calcyon) Xan_ur_permease PF00860.15 KLO07409.1 - 8.3e-31 106.8 26.8 7.9e-19 67.4 7.5 2.3 3 0 0 3 3 3 2 Permease family Sulfate_transp PF00916.15 KLO07409.1 - 0.0029 16.6 4.4 0.0029 16.6 3.0 2.9 2 1 1 3 3 3 1 Sulfate transporter family DUF3493 PF11998.3 KLO07409.1 - 5 7.0 7.4 3.8 7.4 0.4 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3493) F-box-like PF12937.2 KLO07410.1 - 0.00044 19.9 0.1 0.0013 18.4 0.1 1.9 1 0 0 1 1 1 1 F-box-like LRR_8 PF13855.1 KLO07411.1 - 2.2 8.0 13.4 2.8 7.7 0.1 4.9 4 1 1 5 5 5 0 Leucine rich repeat LRR_4 PF12799.2 KLO07411.1 - 7.5 6.2 11.0 18 5.1 0.7 4.8 3 2 1 4 4 4 0 Leucine Rich repeats (2 copies) TerY-C PF15616.1 KLO07412.1 - 0.034 14.0 2.2 0.5 10.2 0.4 2.3 1 1 1 2 2 2 0 TerY-C metal binding domain TF_Zn_Ribbon PF08271.7 KLO07412.1 - 0.096 12.0 3.5 0.1 11.9 0.1 2.4 2 0 0 2 2 2 0 TFIIB zinc-binding zf-C2H2 PF00096.21 KLO07413.1 - 2.1e-29 100.0 71.6 0.0006 20.0 1.0 10.5 10 0 0 10 10 10 10 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KLO07413.1 - 5.4e-17 60.8 66.4 0.035 14.4 1.1 10.5 10 0 0 10 10 10 9 C2H2-type zinc finger zf-H2C2_2 PF13465.1 KLO07413.1 - 1.3e-14 53.6 67.0 7.1e-07 29.2 0.4 11.7 12 0 0 12 12 12 6 Zinc-finger double domain zf-C2H2_jaz PF12171.3 KLO07413.1 - 2.7e-06 27.3 35.9 0.7 10.1 0.3 8.7 8 0 0 8 8 8 5 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 KLO07413.1 - 0.0018 18.4 28.8 2.8 8.2 1.0 8.9 9 0 0 9 9 9 2 Zinc-finger of C2H2 type zf-H2C2_5 PF13909.1 KLO07413.1 - 0.35 11.2 0.0 0.35 11.2 0.0 9.5 10 0 0 10 10 10 0 C2H2-type zinc-finger domain GAGA PF09237.6 KLO07413.1 - 1.7 8.2 7.3 5.6 6.6 0.0 3.9 3 1 1 4 4 4 0 GAGA factor AA_permease_2 PF13520.1 KLO07414.1 - 8.8e-42 143.1 56.2 1.1e-41 142.7 38.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 KLO07414.1 - 1.4e-25 89.5 45.5 1.7e-25 89.3 31.5 1.0 1 0 0 1 1 1 1 Amino acid permease PIG-P PF08510.7 KLO07414.1 - 3.6 7.2 12.3 0.075 12.6 1.0 3.4 3 0 0 3 3 3 0 PIG-P Peptidase_M24 PF00557.19 KLO07415.1 - 1e-55 188.5 0.0 1.4e-55 188.1 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.11 KLO07415.1 - 1.2e-32 112.1 0.0 2.4e-32 111.1 0.0 1.5 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain WLM PF08325.5 KLO07416.1 - 8.4e-38 130.1 0.1 1.7e-37 129.1 0.0 1.4 1 0 0 1 1 1 1 WLM domain ubiquitin PF00240.18 KLO07416.1 - 3.4e-08 32.7 0.1 7.2e-08 31.7 0.1 1.5 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 KLO07416.1 - 0.0019 17.8 0.0 0.0045 16.6 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Peptidase_MA_2 PF13485.1 KLO07416.1 - 0.015 15.3 0.2 0.041 13.9 0.0 1.9 2 0 0 2 2 2 0 Peptidase MA superfamily SprT-like PF10263.4 KLO07416.1 - 0.03 14.0 0.1 0.045 13.4 0.0 1.5 1 0 0 1 1 1 0 SprT-like family DUF45 PF01863.12 KLO07416.1 - 0.047 13.4 0.6 0.25 11.0 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function DUF45 GOLD_2 PF13897.1 KLO07416.1 - 0.14 12.4 0.3 0.37 11.0 0.0 1.7 2 0 0 2 2 2 0 Golgi-dynamics membrane-trafficking DNA_pol_delta_4 PF04081.8 KLO07417.1 - 7.6e-24 84.3 0.9 4.5e-23 81.8 0.6 2.0 1 1 0 1 1 1 1 DNA polymerase delta, subunit 4 BNIP3 PF06553.7 KLO07418.1 - 0.0064 15.9 0.8 0.013 14.9 0.6 1.5 1 0 0 1 1 1 1 BNIP3 p450 PF00067.17 KLO07419.1 - 3.1e-36 124.8 0.0 1.4e-35 122.7 0.0 1.9 1 1 0 1 1 1 1 Cytochrome P450 BatD PF13584.1 KLO07420.1 - 0.0025 16.4 0.2 0.0037 15.9 0.1 1.2 1 0 0 1 1 1 1 Oxygen tolerance TRP PF06011.7 KLO07420.1 - 0.03 12.8 0.1 0.036 12.6 0.1 1.1 1 0 0 1 1 1 0 Transient receptor potential (TRP) ion channel STT3 PF02516.9 KLO07421.1 - 1.4e-129 433.2 34.9 1.1e-121 407.1 23.1 2.1 1 1 1 2 2 2 2 Oligosaccharyl transferase STT3 subunit Ribonuc_P_40 PF08584.6 KLO07422.1 - 6.9e-26 90.8 0.7 1.5e-23 83.2 0.5 2.1 1 1 0 1 1 1 1 Ribonuclease P 40kDa (Rpp40) subunit Cas_Csm6 PF09659.5 KLO07422.1 - 0.0083 14.7 0.0 0.012 14.3 0.0 1.1 1 0 0 1 1 1 1 CRISPR-associated protein (Cas_Csm6) UPF0081 PF03652.10 KLO07422.1 - 0.085 12.9 0.0 0.13 12.4 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0081) Pantoate_ligase PF02569.10 KLO07423.1 - 1.2e-85 286.6 0.0 1.6e-85 286.3 0.0 1.1 1 0 0 1 1 1 1 Pantoate-beta-alanine ligase UCH PF00443.24 KLO07424.1 - 3.4e-71 239.4 0.0 4.9e-71 238.9 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 KLO07424.1 - 4.4e-22 78.8 0.0 3.7e-21 75.8 0.0 2.0 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Rhodanese PF00581.15 KLO07424.1 - 3.4e-06 27.3 0.0 7.9e-06 26.2 0.0 1.7 1 0 0 1 1 1 1 Rhodanese-like domain zf-MIZ PF02891.15 KLO07424.1 - 0.0088 15.5 0.9 0.018 14.5 0.6 1.5 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger zf-HC5HC2H_2 PF13832.1 KLO07425.1 - 2.5e-14 53.2 16.7 2.8e-13 49.8 0.9 4.2 3 0 0 3 3 3 2 PHD-zinc-finger like domain BAH PF01426.13 KLO07425.1 - 1.6e-12 47.2 0.0 2.8e-12 46.4 0.0 1.4 1 0 0 1 1 1 1 BAH domain PHD PF00628.24 KLO07425.1 - 1.7e-10 40.3 49.7 2.3e-07 30.4 7.4 6.3 6 0 0 6 6 6 3 PHD-finger zf-HC5HC2H PF13771.1 KLO07425.1 - 3.8e-09 36.5 1.0 3.8e-09 36.5 0.7 4.5 4 1 0 4 4 4 2 PHD-like zinc-binding domain GATA PF00320.22 KLO07425.1 - 2.9e-05 23.3 3.7 2.9e-05 23.3 2.6 4.5 4 0 0 4 4 4 1 GATA zinc finger PHD_2 PF13831.1 KLO07425.1 - 0.0086 15.3 2.0 0.0086 15.3 1.4 5.6 7 0 0 7 7 7 2 PHD-finger SET PF00856.23 KLO07426.1 - 6.1e-13 49.4 0.1 1.6e-09 38.2 0.0 2.2 2 0 0 2 2 2 2 SET domain DUF4592 PF15262.1 KLO07426.1 - 4.7 7.7 8.9 0.15 12.6 0.6 2.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4592) CAP_GLY PF01302.20 KLO07427.1 - 4.1e-25 87.2 2.9 6.8e-25 86.5 1.5 1.8 3 0 0 3 3 3 1 CAP-Gly domain Ubiquitin_2 PF14560.1 KLO07427.1 - 2.6e-19 69.2 0.0 6.1e-19 68.0 0.0 1.6 2 0 0 2 2 2 1 Ubiquitin-like domain ubiquitin PF00240.18 KLO07427.1 - 0.0042 16.4 0.0 0.16 11.3 0.0 2.6 3 0 0 3 3 3 1 Ubiquitin family Lipase_3 PF01764.20 KLO07428.1 - 1.5e-18 66.8 0.0 2e-18 66.3 0.0 1.2 1 0 0 1 1 1 1 Lipase (class 3) DUF2974 PF11187.3 KLO07428.1 - 0.031 13.6 0.1 1 8.6 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2974) Abhydrolase_6 PF12697.2 KLO07428.1 - 0.031 14.1 0.2 0.046 13.6 0.1 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_8 PF06259.7 KLO07428.1 - 0.059 12.8 0.2 0.13 11.7 0.1 1.6 1 0 0 1 1 1 0 Alpha/beta hydrolase PGAP1 PF07819.8 KLO07428.1 - 0.11 12.0 0.1 0.18 11.3 0.0 1.2 1 0 0 1 1 1 0 PGAP1-like protein Lipase_3 PF01764.20 KLO07429.1 - 7.8e-21 74.1 0.0 1.1e-20 73.7 0.0 1.2 1 0 0 1 1 1 1 Lipase (class 3) Esterase_phd PF10503.4 KLO07429.1 - 0.006 15.8 0.9 0.0089 15.2 0.6 1.2 1 0 0 1 1 1 1 Esterase PHB depolymerase Abhydrolase_6 PF12697.2 KLO07429.1 - 0.015 15.1 0.2 0.022 14.6 0.1 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family SFTA2 PF15210.1 KLO07429.1 - 0.076 12.6 0.0 0.28 10.8 0.0 1.9 1 0 0 1 1 1 0 Surfactant-associated protein 2 Fer4_6 PF12837.2 KLO07431.1 - 0.062 13.2 0.9 0.098 12.5 0.6 1.3 1 0 0 1 1 1 0 4Fe-4S binding domain Fer4_3 PF12798.2 KLO07431.1 - 0.092 13.3 2.3 0.14 12.7 1.6 1.3 1 0 0 1 1 1 0 4Fe-4S binding domain Fer4_2 PF12797.2 KLO07431.1 - 0.36 10.8 2.6 0.61 10.1 1.8 1.4 1 0 0 1 1 1 0 4Fe-4S binding domain Exo_endo_phos PF03372.18 KLO07432.1 - 2e-20 73.8 0.0 4e-20 72.7 0.0 1.5 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.1 KLO07432.1 - 2.3e-09 36.8 0.5 5.8e-09 35.5 0.0 2.0 2 0 0 2 2 2 1 Endonuclease-reverse transcriptase zf-GRF PF06839.7 KLO07432.1 - 2.1e-06 27.5 3.1 0.00024 20.9 0.4 2.5 2 0 0 2 2 2 2 GRF zinc finger Thymidylate_kin PF02223.12 KLO07433.1 - 5.4e-46 156.3 0.0 6.2e-46 156.1 0.0 1.0 1 0 0 1 1 1 1 Thymidylate kinase AAA_28 PF13521.1 KLO07433.1 - 0.00071 19.5 0.0 0.0011 18.9 0.0 1.3 1 0 0 1 1 1 1 AAA domain KTI12 PF08433.5 KLO07433.1 - 0.0029 16.8 0.0 0.01 15.0 0.0 1.8 2 1 0 2 2 2 1 Chromatin associated protein KTI12 PRK PF00485.13 KLO07433.1 - 0.016 14.7 0.0 0.036 13.6 0.0 1.5 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family APS_kinase PF01583.15 KLO07433.1 - 0.048 13.3 0.0 0.1 12.2 0.0 1.5 1 0 0 1 1 1 0 Adenylylsulphate kinase CotJB PF12652.2 KLO07433.1 - 0.071 13.1 0.0 0.13 12.3 0.0 1.4 1 0 0 1 1 1 0 CotJB protein AAA_18 PF13238.1 KLO07433.1 - 0.11 12.7 0.1 0.42 10.9 0.1 2.1 1 1 0 1 1 1 0 AAA domain zf-met PF12874.2 KLO07437.1 - 0.0026 17.8 1.8 0.0076 16.4 0.1 2.4 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.1 KLO07437.1 - 0.0097 15.7 0.6 0.023 14.6 0.4 1.7 1 0 0 1 1 1 1 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 KLO07437.1 - 0.0099 16.0 0.6 0.032 14.3 0.1 2.1 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.1 KLO07437.1 - 0.011 15.9 1.1 0.052 13.9 0.8 2.2 1 0 0 1 1 1 0 C2H2-type zinc finger zf-C2H2 PF00096.21 KLO07437.1 - 0.11 12.9 2.6 0.17 12.2 0.7 2.2 2 0 0 2 2 2 0 Zinc finger, C2H2 type SRP-alpha_N PF04086.8 KLO07437.1 - 3 7.1 7.3 0.85 8.9 1.9 1.8 1 1 1 2 2 2 0 Signal recognition particle, alpha subunit, N-terminal MKT1_C PF12246.3 KLO07438.1 - 2.3e-61 206.9 0.0 3.5e-61 206.2 0.0 1.3 1 0 0 1 1 1 1 Temperature dependent protein affecting M2 dsRNA replication MKT1_N PF12247.3 KLO07438.1 - 1.4e-22 79.8 0.0 3e-22 78.7 0.0 1.6 1 0 0 1 1 1 1 Temperature dependent protein affecting M2 dsRNA replication XPG_I PF00867.13 KLO07438.1 - 1.1e-09 38.2 0.0 2.4e-09 37.0 0.0 1.6 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.12 KLO07438.1 - 9.1e-08 32.2 0.0 3.2e-07 30.5 0.0 1.9 1 0 0 1 1 1 1 XPG N-terminal domain DUF3330 PF11809.3 KLO07439.1 - 0.087 12.6 0.5 0.21 11.4 0.4 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF3330) P19Arf_N PF07392.7 KLO07439.1 - 0.22 11.7 1.0 0.3 11.2 0.0 1.6 2 0 0 2 2 2 0 Cyclin-dependent kinase inhibitor 2a p19Arf N-terminus F-box-like PF12937.2 KLO07440.1 - 0.0012 18.5 0.1 0.0012 18.5 0.1 2.9 3 0 0 3 3 3 1 F-box-like tRNA-synt_2b PF00587.20 KLO07441.1 - 1.6e-42 144.9 0.0 2.5e-42 144.3 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 KLO07441.1 - 2.3e-19 69.1 0.1 5.1e-19 68.0 0.1 1.6 1 0 0 1 1 1 1 Anticodon binding domain TGS PF02824.16 KLO07441.1 - 2e-10 40.3 0.0 4.9e-10 39.0 0.0 1.7 1 0 0 1 1 1 1 TGS domain tRNA_SAD PF07973.9 KLO07441.1 - 3.3e-07 30.0 0.0 6.3e-07 29.1 0.0 1.5 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain Thymidylate_kin PF02223.12 KLO07443.1 - 3.1e-46 157.1 0.0 3.7e-46 156.8 0.0 1.1 1 0 0 1 1 1 1 Thymidylate kinase AAA_28 PF13521.1 KLO07443.1 - 0.0015 18.5 0.0 0.0022 17.9 0.0 1.3 1 0 0 1 1 1 1 AAA domain KTI12 PF08433.5 KLO07443.1 - 0.0031 16.7 0.0 0.0094 15.1 0.0 1.8 2 1 0 2 2 2 1 Chromatin associated protein KTI12 PRK PF00485.13 KLO07443.1 - 0.018 14.6 0.0 0.036 13.6 0.0 1.5 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family APS_kinase PF01583.15 KLO07443.1 - 0.045 13.4 0.0 0.084 12.5 0.0 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA_33 PF13671.1 KLO07443.1 - 0.13 12.1 0.0 0.27 11.0 0.0 1.6 1 1 0 1 1 1 0 AAA domain UQ_con PF00179.21 KLO07444.1 - 2e-25 88.8 0.0 2.6e-25 88.4 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Pro_isomerase PF00160.16 KLO07445.1 - 4.1e-40 137.5 0.1 1.4e-39 135.8 0.0 1.9 2 0 0 2 2 2 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD SlyX PF04102.7 KLO07445.1 - 5.9 7.3 7.8 0.31 11.4 1.1 2.1 2 0 0 2 2 2 0 SlyX DUF1569 PF07606.6 KLO07446.1 - 0.11 12.3 1.3 2.2 8.1 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF1569) PX PF00787.19 KLO07446.1 - 1.6 8.5 5.8 2.8 7.7 2.4 2.2 1 1 1 2 2 2 0 PX domain SPX PF03105.14 KLO07446.1 - 1.7 8.3 7.3 2.6 7.7 5.0 1.4 1 1 0 1 1 1 0 SPX domain DUF2999 PF11212.3 KLO07447.1 - 0.018 15.0 0.0 0.026 14.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2999) VPS9 PF02204.13 KLO07449.1 - 2.2e-17 62.9 0.0 2.4e-16 59.6 0.0 2.2 1 1 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain PBD PF00786.23 KLO07451.1 - 7e-24 84.0 0.1 1.1e-23 83.4 0.1 1.3 1 0 0 1 1 1 1 P21-Rho-binding domain Pkinase PF00069.20 KLO07452.1 - 1.8e-69 233.7 0.0 2.8e-69 233.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KLO07452.1 - 3e-47 160.8 0.0 5e-47 160.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KLO07452.1 - 2.2e-05 23.5 0.0 3.6e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 KLO07452.1 - 0.0021 17.8 0.2 0.035 13.8 0.1 2.2 1 1 1 2 2 2 1 Phosphotransferase enzyme family DUF3530 PF12048.3 KLO07452.1 - 0.011 14.7 0.2 0.018 14.0 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3530) Kdo PF06293.9 KLO07452.1 - 0.017 14.2 0.1 0.048 12.7 0.0 1.7 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF1280 PF06918.9 KLO07452.1 - 0.018 14.2 0.5 2.1 7.4 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1280) DUF605 PF04652.11 KLO07452.1 - 0.057 12.8 14.6 0.076 12.3 10.1 1.1 1 0 0 1 1 1 0 Vta1 like DSHCT PF08148.7 KLO07452.1 - 0.1 11.8 0.0 0.2 10.8 0.0 1.4 1 0 0 1 1 1 0 DSHCT (NUC185) domain PI3_PI4_kinase PF00454.22 KLO07453.1 - 6.3e-44 150.1 0.0 1.4e-43 149.0 0.0 1.6 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase TAN PF11640.3 KLO07453.1 - 4.6e-26 91.4 0.0 2.2e-25 89.2 0.0 2.2 2 0 0 2 2 2 1 Telomere-length maintenance and DNA damage repair FATC PF02260.15 KLO07453.1 - 6.8e-13 47.7 0.1 4.1e-12 45.3 0.0 2.2 2 0 0 2 2 2 1 FATC domain Peptidase_S10 PF00450.17 KLO07454.1 - 2.5e-68 231.1 0.0 5.3e-68 230.0 0.0 1.5 1 1 0 1 1 1 1 Serine carboxypeptidase Peptidase_S10 PF00450.17 KLO07455.1 - 1.3e-67 228.8 0.0 2.7e-67 227.7 0.0 1.5 1 1 0 1 1 1 1 Serine carboxypeptidase Peptidase_M20 PF01546.23 KLO07456.1 - 1e-08 34.9 0.2 1.5e-08 34.3 0.1 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 KLO07456.1 - 1.4e-08 34.4 0.0 2.7e-08 33.5 0.0 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain GPW_gp25 PF04965.9 KLO07456.1 - 0.017 14.6 0.0 0.047 13.2 0.0 1.7 1 0 0 1 1 1 0 Gene 25-like lysozyme Glyco_hydro_14 PF01373.12 KLO07456.1 - 0.054 12.2 0.0 0.085 11.5 0.0 1.3 1 0 0 1 1 1 0 Glycosyl hydrolase family 14 SUI1 PF01253.17 KLO07457.1 - 6.2e-20 70.7 2.0 1.3e-19 69.7 1.4 1.6 1 0 0 1 1 1 1 Translation initiation factor SUI1 Pkinase PF00069.20 KLO07459.1 - 6.5e-43 146.7 0.0 8e-43 146.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KLO07459.1 - 2.2e-39 135.0 0.0 2.8e-39 134.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KLO07459.1 - 9.5e-06 24.7 0.0 1.3e-05 24.2 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Carn_acyltransf PF00755.15 KLO07461.1 - 5.4e-138 460.6 0.0 8e-138 460.1 0.0 1.2 1 1 0 1 1 1 1 Choline/Carnitine o-acyltransferase Marek_SORF3 PF07153.6 KLO07461.1 - 0.14 10.8 0.0 0.22 10.1 0.0 1.2 1 0 0 1 1 1 0 Marek's disease-like virus SORF3 protein Abhydrolase_3 PF07859.8 KLO07463.1 - 5.7e-17 62.0 0.1 1.1e-16 61.1 0.1 1.5 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KLO07463.1 - 1.7e-11 44.0 0.0 2.7e-11 43.4 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Chlorophyllase2 PF12740.2 KLO07463.1 - 9.2e-07 27.9 0.0 1.4e-06 27.4 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase enzyme Abhydrolase_6 PF12697.2 KLO07463.1 - 6.8e-06 26.1 1.9 9.6e-06 25.6 1.3 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 KLO07463.1 - 1.6e-05 24.2 0.0 0.15 11.2 0.0 2.6 3 0 0 3 3 3 2 Prolyl oligopeptidase family COesterase PF00135.23 KLO07463.1 - 7.3e-05 21.6 0.0 0.032 12.9 0.0 2.1 2 0 0 2 2 2 2 Carboxylesterase family Esterase_phd PF10503.4 KLO07463.1 - 0.078 12.2 0.0 0.9 8.7 0.0 2.3 2 0 0 2 2 2 0 Esterase PHB depolymerase Chlorophyllase PF07224.6 KLO07463.1 - 0.083 11.6 0.0 0.13 11.0 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase Sugar_tr PF00083.19 KLO07465.1 - 8.9e-47 159.6 14.1 2.7e-46 158.0 9.8 1.6 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KLO07465.1 - 2.4e-22 79.1 16.5 4.3e-21 75.0 10.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Usher PF00577.15 KLO07465.1 - 0.077 11.7 0.0 0.12 11.0 0.0 1.2 1 0 0 1 1 1 0 Outer membrane usher protein SET PF00856.23 KLO07467.1 - 5.7e-09 36.4 0.0 2.2e-08 34.5 0.0 2.0 2 0 0 2 2 2 1 SET domain TPR_11 PF13414.1 KLO07467.1 - 7.9e-06 25.4 0.0 8.4e-05 22.1 0.0 2.5 3 0 0 3 3 3 1 TPR repeat SET PF00856.23 KLO07468.1 - 6e-09 36.4 0.0 2.1e-07 31.4 0.0 2.9 3 0 0 3 3 3 1 SET domain TPR_11 PF13414.1 KLO07468.1 - 2.1e-05 24.0 0.0 5.1e-05 22.8 0.0 1.6 1 0 0 1 1 1 1 TPR repeat SET PF00856.23 KLO07469.1 - 3.2e-10 40.5 0.0 3.5e-09 37.1 0.0 2.6 1 1 0 1 1 1 1 SET domain TPR_11 PF13414.1 KLO07469.1 - 2.2e-05 24.0 0.0 5.2e-05 22.8 0.0 1.6 1 0 0 1 1 1 1 TPR repeat SET PF00856.23 KLO07472.1 - 2.4e-06 27.9 0.0 9.7e-06 25.9 0.0 2.0 2 0 0 2 2 2 1 SET domain TPR_11 PF13414.1 KLO07472.1 - 2.3e-05 23.9 0.0 8.1e-05 22.1 0.0 1.9 2 0 0 2 2 2 1 TPR repeat SET PF00856.23 KLO07473.1 - 3.6e-10 40.3 0.0 9.3e-09 35.7 0.0 2.7 3 0 0 3 3 3 1 SET domain TPR_11 PF13414.1 KLO07473.1 - 3.3e-06 26.6 0.0 7.5e-06 25.5 0.0 1.6 1 0 0 1 1 1 1 TPR repeat SET PF00856.23 KLO07474.1 - 1.6e-08 35.0 0.0 1.5e-07 31.8 0.0 2.4 2 0 0 2 2 2 1 SET domain TPR_11 PF13414.1 KLO07474.1 - 3e-05 23.5 0.1 0.0001 21.8 0.0 1.9 2 0 0 2 2 2 1 TPR repeat DUF1793 PF08760.6 KLO07475.1 - 2.4e-20 73.1 0.0 4.2e-20 72.2 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1793) Bac_rhamnosid PF05592.6 KLO07475.1 - 0.0017 16.6 0.0 0.0028 15.9 0.0 1.2 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase NR_Repeat PF14046.1 KLO07476.1 - 0.037 13.7 0.6 0.91 9.3 0.0 2.5 2 0 0 2 2 2 0 Nuclear receptor repeat ox_reductase_C PF08635.5 KLO07476.1 - 0.077 12.4 0.0 0.14 11.5 0.0 1.4 1 0 0 1 1 1 0 Putative oxidoreductase C terminal zf-C2H2 PF00096.21 KLO07476.1 - 0.079 13.3 0.4 0.3 11.5 0.3 2.0 1 0 0 1 1 1 0 Zinc finger, C2H2 type DUF4105 PF13387.1 KLO07477.1 - 0.049 12.8 0.1 0.057 12.6 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4105) PDE8 PF08629.5 KLO07477.1 - 0.16 11.7 0.4 0.25 11.1 0.3 1.3 1 0 0 1 1 1 0 PDE8 phosphodiesterase BolA PF01722.13 KLO07478.1 - 2.2e-15 56.3 0.0 1.8e-14 53.4 0.0 2.1 2 0 0 2 2 2 1 BolA-like protein COX15-CtaA PF02628.10 KLO07479.1 - 8.4e-90 300.6 11.2 1e-89 300.4 7.8 1.1 1 0 0 1 1 1 1 Cytochrome oxidase assembly protein NADH-u_ox-rdase PF10785.4 KLO07479.1 - 3.1 8.0 6.6 6.6 7.0 0.1 3.1 3 0 0 3 3 3 0 NADH-ubiquinone oxidoreductase complex I, 21 kDa subunit FAD_binding_4 PF01565.18 KLO07481.1 - 1.4e-28 99.1 3.9 1.4e-28 99.1 2.7 1.5 2 0 0 2 2 2 1 FAD binding domain BBE PF08031.7 KLO07481.1 - 3.3e-09 36.5 0.2 6.8e-09 35.5 0.2 1.5 1 0 0 1 1 1 1 Berberine and berberine like Cytokin-bind PF09265.5 KLO07481.1 - 0.067 12.3 0.0 0.1 11.7 0.0 1.2 1 0 0 1 1 1 0 Cytokinin dehydrogenase 1, FAD and cytokinin binding MS_channel PF00924.13 KLO07482.1 - 3.6e-18 65.6 0.1 6.6e-18 64.7 0.1 1.4 1 0 0 1 1 1 1 Mechanosensitive ion channel EF-hand_1 PF00036.27 KLO07482.1 - 6.5e-06 25.0 0.1 1.5e-05 23.9 0.0 1.7 1 0 0 1 1 1 1 EF hand EF-hand_7 PF13499.1 KLO07482.1 - 0.0001 22.3 0.1 0.00032 20.7 0.0 1.8 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.1 KLO07482.1 - 0.00013 21.5 0.0 0.00048 19.7 0.0 2.0 1 0 0 1 1 1 1 EF-hand domain EF-hand_5 PF13202.1 KLO07482.1 - 0.00019 20.6 0.1 0.00044 19.4 0.1 1.6 1 0 0 1 1 1 1 EF hand EF-hand_8 PF13833.1 KLO07482.1 - 0.0014 18.2 0.0 0.003 17.1 0.0 1.5 1 0 0 1 1 1 1 EF-hand domain pair PBP1_TM PF14812.1 KLO07482.1 - 0.035 14.3 0.7 5.5 7.3 0.1 2.8 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal BRI3BP PF14965.1 KLO07482.1 - 0.15 11.4 3.2 0.22 10.9 1.3 1.8 2 0 0 2 2 2 0 Negative regulator of p53/TP53 FAD_binding_4 PF01565.18 KLO07485.1 - 1e-31 109.2 2.7 1.3e-30 105.6 2.7 2.2 3 0 0 3 3 3 1 FAD binding domain BBE PF08031.7 KLO07485.1 - 6.2e-09 35.6 0.1 1.6e-08 34.3 0.1 1.6 1 0 0 1 1 1 1 Berberine and berberine like Cytokin-bind PF09265.5 KLO07485.1 - 0.063 12.4 0.0 0.11 11.6 0.0 1.3 1 0 0 1 1 1 0 Cytokinin dehydrogenase 1, FAD and cytokinin binding FAD_binding_4 PF01565.18 KLO07486.1 - 1.2e-22 79.9 1.7 2e-22 79.1 0.7 1.7 2 0 0 2 2 2 1 FAD binding domain BBE PF08031.7 KLO07486.1 - 7.7e-10 38.5 0.0 1.8e-09 37.3 0.0 1.6 1 0 0 1 1 1 1 Berberine and berberine like Abhydrolase_5 PF12695.2 KLO07486.1 - 0.044 13.5 0.1 0.086 12.5 0.1 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase family Cytokin-bind PF09265.5 KLO07486.1 - 0.11 11.5 0.0 0.17 11.0 0.0 1.2 1 0 0 1 1 1 0 Cytokinin dehydrogenase 1, FAD and cytokinin binding FAD_binding_4 PF01565.18 KLO07487.1 - 6.2e-24 84.0 1.4 6.2e-24 84.0 0.9 1.6 2 0 0 2 2 2 1 FAD binding domain BBE PF08031.7 KLO07487.1 - 6.8e-08 32.2 0.2 1.3e-07 31.3 0.1 1.4 1 0 0 1 1 1 1 Berberine and berberine like Cytokin-bind PF09265.5 KLO07487.1 - 0.018 14.1 0.0 0.025 13.7 0.0 1.2 1 0 0 1 1 1 0 Cytokinin dehydrogenase 1, FAD and cytokinin binding Zip PF02535.17 KLO07489.1 - 0.058 12.3 2.6 0.068 12.1 1.8 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter GTP_EFTU PF00009.22 KLO07490.1 - 9.8e-34 116.4 0.0 1.3e-33 115.9 0.0 1.1 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 KLO07490.1 - 3.9e-08 33.3 0.1 1.2e-06 28.6 0.1 2.4 1 1 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 KLO07490.1 - 2.6e-05 24.2 0.1 4.6e-05 23.4 0.1 1.4 1 0 0 1 1 1 1 Elongation factor Tu domain 2 GTP_EFTU_D4 PF14578.1 KLO07490.1 - 0.0023 17.5 0.0 0.0046 16.5 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu domain 4 MMR_HSR1 PF01926.18 KLO07490.1 - 0.027 14.4 0.0 0.049 13.5 0.0 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase HBS1_N PF08938.5 KLO07492.1 - 1.3e-10 41.2 1.8 2.6e-10 40.2 1.2 1.5 1 0 0 1 1 1 1 HBS1 N-terminus SSB PF00436.20 KLO07493.1 - 5.2e-14 51.9 0.0 7.1e-14 51.5 0.0 1.2 1 0 0 1 1 1 1 Single-strand binding protein family Pex2_Pex12 PF04757.9 KLO07495.1 - 1.6e-50 171.6 7.1 2.1e-50 171.3 4.9 1.1 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4_2 PF13923.1 KLO07495.1 - 8e-07 28.9 2.3 1.3e-06 28.2 1.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KLO07495.1 - 3.3e-06 26.6 0.6 5.2e-06 26.0 0.4 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KLO07495.1 - 3.3e-06 26.8 1.8 5.5e-06 26.1 1.3 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_4 PF15227.1 KLO07495.1 - 0.0026 17.6 3.1 0.0041 16.9 2.1 1.3 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.20 KLO07495.1 - 0.003 17.1 1.7 0.0048 16.5 1.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) DUF1641 PF07849.6 KLO07495.1 - 0.096 12.3 0.1 3.8 7.1 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1641) DUF2685 PF10886.3 KLO07495.1 - 0.28 11.2 1.8 0.52 10.3 1.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2685) zf-RING_4 PF14570.1 KLO07495.1 - 0.68 9.5 8.0 1.9 8.1 0.6 3.0 3 0 0 3 3 3 0 RING/Ubox like zinc-binding domain SPX PF03105.14 KLO07496.1 - 2.5e-34 119.3 0.9 8.6e-20 71.6 0.0 2.2 1 1 1 2 2 2 2 SPX domain Pectinesterase PF01095.14 KLO07497.1 - 1.3e-35 122.4 1.4 4.1e-31 107.6 0.7 2.1 2 0 0 2 2 2 2 Pectinesterase Pectate_lyase_3 PF12708.2 KLO07497.1 - 0.099 12.7 6.1 0.086 12.9 2.9 1.8 2 0 0 2 2 2 0 Pectate lyase superfamily protein Peptidase_S8 PF00082.17 KLO07498.1 - 2.4e-46 158.1 2.5 3.8e-46 157.5 1.7 1.3 1 0 0 1 1 1 1 Subtilase family P_proprotein PF01483.15 KLO07498.1 - 5.2e-30 103.0 0.3 1.1e-29 102.0 0.2 1.6 1 0 0 1 1 1 1 Proprotein convertase P-domain DUF2914 PF11141.3 KLO07498.1 - 0.047 13.2 0.1 0.1 12.1 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2914) PRKCSH-like PF12999.2 KLO07499.1 - 1.9e-49 167.5 1.1 5.7e-49 166.0 0.7 1.7 1 0 0 1 1 1 1 Glucosidase II beta subunit-like PRKCSH_1 PF13015.1 KLO07499.1 - 9.1e-26 90.1 0.0 2.2e-25 88.9 0.0 1.6 1 0 0 1 1 1 1 Glucosidase II beta subunit-like protein PRKCSH PF07915.8 KLO07499.1 - 3.4e-08 34.1 1.4 3.4e-08 34.1 1.0 2.2 2 0 0 2 2 2 1 Glucosidase II beta subunit-like protein Ldl_recept_a PF00057.13 KLO07499.1 - 0.27 11.1 14.4 2 8.3 0.9 2.7 2 0 0 2 2 2 0 Low-density lipoprotein receptor domain class A Mnd1 PF03962.10 KLO07499.1 - 0.28 10.8 8.0 0.029 14.0 1.8 2.0 2 0 0 2 2 2 0 Mnd1 family DDHD PF02862.12 KLO07499.1 - 0.49 10.1 4.3 0.14 11.9 0.7 1.7 2 0 0 2 2 2 0 DDHD domain Ribosomal_S25 PF03297.10 KLO07500.1 - 5.2e-37 126.0 4.8 6.7e-37 125.7 3.3 1.1 1 0 0 1 1 1 1 S25 ribosomal protein Ftsk_gamma PF09397.5 KLO07500.1 - 0.00075 19.1 0.1 0.0014 18.3 0.1 1.5 1 0 0 1 1 1 1 Ftsk gamma domain Rrf2 PF02082.15 KLO07500.1 - 0.037 14.1 0.1 0.059 13.4 0.1 1.3 1 0 0 1 1 1 0 Transcriptional regulator MarR PF01047.17 KLO07500.1 - 0.043 13.5 0.1 0.064 12.9 0.0 1.2 1 0 0 1 1 1 0 MarR family MarR_2 PF12802.2 KLO07500.1 - 0.046 13.3 0.1 0.073 12.7 0.0 1.3 1 0 0 1 1 1 0 MarR family DUF637 PF04830.8 KLO07500.1 - 0.049 13.2 1.2 0.093 12.3 0.6 1.6 2 0 0 2 2 2 0 Possible hemagglutinin (DUF637) Fe_dep_repress PF01325.14 KLO07500.1 - 0.068 13.1 0.0 0.12 12.3 0.0 1.3 1 0 0 1 1 1 0 Iron dependent repressor, N-terminal DNA binding domain HTH_13 PF11972.3 KLO07500.1 - 0.15 11.9 0.1 0.28 11.0 0.0 1.4 1 0 0 1 1 1 0 HTH DNA binding domain Apq12 PF12716.2 KLO07501.1 - 0.61 9.8 2.3 0.82 9.4 1.6 1.2 1 0 0 1 1 1 0 Nuclear pore assembly and biogenesis HIG_1_N PF04588.8 KLO07502.1 - 5.4e-07 29.2 0.5 1.2e-06 28.1 0.4 1.6 1 0 0 1 1 1 1 Hypoxia induced protein conserved region DUF3681 PF12442.3 KLO07502.1 - 0.011 15.9 2.1 2.3 8.4 0.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3681) HIG_1_N PF04588.8 KLO07503.1 - 0.0011 18.6 0.7 0.0018 17.9 0.1 1.8 2 0 0 2 2 2 1 Hypoxia induced protein conserved region FlgN PF05130.7 KLO07504.1 - 2.3e-05 24.6 8.7 0.0008 19.6 0.1 2.3 2 0 0 2 2 2 2 FlgN protein Filament PF00038.16 KLO07504.1 - 0.00038 20.0 7.4 0.0077 15.7 1.4 2.2 2 0 0 2 2 2 2 Intermediate filament protein Taxilin PF09728.4 KLO07504.1 - 0.0093 15.0 6.4 0.17 10.9 1.4 2.1 2 0 0 2 2 2 2 Myosin-like coiled-coil protein Leu_zip PF15294.1 KLO07504.1 - 0.011 14.8 6.2 0.037 13.1 0.8 2.1 2 0 0 2 2 2 0 Leucine zipper DUF4140 PF13600.1 KLO07504.1 - 0.012 16.0 8.1 0.81 10.1 2.2 2.9 2 1 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) Cortex-I_coil PF09304.5 KLO07504.1 - 0.038 14.0 7.9 0.83 9.7 1.5 2.3 2 0 0 2 2 2 0 Cortexillin I, coiled coil IncA PF04156.9 KLO07504.1 - 0.04 13.4 7.7 0.49 9.9 1.0 2.3 2 0 0 2 2 2 0 IncA protein bZIP_1 PF00170.16 KLO07504.1 - 0.064 13.2 11.9 0.31 11.0 1.1 3.4 2 1 1 3 3 3 0 bZIP transcription factor Shugoshin_N PF07558.6 KLO07504.1 - 0.094 12.4 0.1 2.3 7.9 0.0 2.7 3 0 0 3 3 3 0 Shugoshin N-terminal coiled-coil region ATP-synt_D PF01813.12 KLO07504.1 - 0.11 11.9 0.1 0.11 11.9 0.1 2.1 2 0 0 2 2 2 0 ATP synthase subunit D DUF484 PF04340.7 KLO07504.1 - 0.22 10.9 3.5 1.1 8.6 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function, DUF484 DUF972 PF06156.8 KLO07504.1 - 0.25 11.6 7.2 1.5 9.2 0.1 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF972) V_ATPase_I PF01496.14 KLO07504.1 - 0.3 8.8 2.2 5.9 4.6 0.1 2.0 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family Cep57_MT_bd PF06657.8 KLO07504.1 - 0.31 11.0 7.2 0.57 10.1 0.2 2.7 2 1 1 3 3 3 0 Centrosome microtubule-binding domain of Cep57 DUF964 PF06133.6 KLO07504.1 - 0.54 10.3 4.7 0.22 11.5 0.5 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF964) Prefoldin PF02996.12 KLO07504.1 - 0.56 9.8 6.9 0.16 11.6 1.2 2.3 2 0 0 2 2 2 0 Prefoldin subunit Tropomyosin PF00261.15 KLO07504.1 - 1.1 8.3 12.8 0.26 10.3 2.6 2.1 2 0 0 2 2 2 0 Tropomyosin Kinesin-relat_1 PF12711.2 KLO07504.1 - 1.2 9.6 7.4 0.93 9.9 0.8 2.4 2 0 0 2 2 2 0 Kinesin motor DUF4200 PF13863.1 KLO07504.1 - 1.2 9.0 13.2 1.6 8.6 3.1 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF4200) ADIP PF11559.3 KLO07504.1 - 1.4 8.8 10.6 1.5 8.7 1.9 2.3 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding DUF4164 PF13747.1 KLO07504.1 - 1.6 8.9 9.9 2 8.6 2.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4164) TMF_TATA_bd PF12325.3 KLO07504.1 - 1.8 8.3 9.6 1.4 8.6 0.2 2.7 2 1 0 2 2 2 0 TATA element modulatory factor 1 TATA binding bZIP_2 PF07716.10 KLO07504.1 - 2.2 8.1 11.8 13 5.6 1.5 3.5 3 0 0 3 3 3 0 Basic region leucine zipper M PF02370.11 KLO07504.1 - 4.2 8.0 10.9 40 5.0 0.0 4.1 3 2 1 4 4 4 0 M protein repeat MAD PF05557.8 KLO07504.1 - 4.3 5.3 14.7 0.29 9.1 2.2 2.4 2 1 1 3 3 3 0 Mitotic checkpoint protein GrpE PF01025.14 KLO07504.1 - 4.6 6.7 7.2 12 5.3 0.8 2.4 2 0 0 2 2 2 0 GrpE CENP-H PF05837.7 KLO07504.1 - 4.9 7.3 9.9 4.6 7.4 0.6 2.9 2 1 1 3 3 3 0 Centromere protein H (CENP-H) BRE1 PF08647.6 KLO07504.1 - 4.9 7.1 8.3 15 5.6 0.4 2.8 2 1 1 3 3 3 0 BRE1 E3 ubiquitin ligase FUSC PF04632.7 KLO07504.1 - 5.5 5.2 9.7 2 6.7 3.1 2.0 2 0 0 2 2 2 0 Fusaric acid resistance protein family DivIVA PF05103.8 KLO07504.1 - 5.6 7.0 12.1 6.7 6.7 1.5 2.9 2 1 1 3 3 3 0 DivIVA protein DivIC PF04977.10 KLO07504.1 - 5.8 6.4 13.5 8.2 5.9 0.3 3.2 2 1 1 3 3 3 0 Septum formation initiator Prefoldin_2 PF01920.15 KLO07504.1 - 5.8 6.7 9.6 0.5 10.1 0.9 2.7 2 1 1 3 3 3 0 Prefoldin subunit Med21 PF11221.3 KLO07504.1 - 5.9 6.8 8.3 9.7 6.1 1.5 2.5 2 0 0 2 2 2 0 Subunit 21 of Mediator complex TMF_DNA_bd PF12329.3 KLO07504.1 - 7.6 6.4 14.2 2.2 8.1 2.1 2.9 2 1 0 2 2 2 0 TATA element modulatory factor 1 DNA binding APG6 PF04111.7 KLO07504.1 - 8.7 5.2 11.3 2.7 6.9 2.2 2.5 2 1 0 2 2 2 0 Autophagy protein Apg6 Cyt-b5 PF00173.23 KLO07506.1 - 1.2e-22 79.4 0.0 1.7e-22 79.0 0.0 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain CDC14 PF08045.6 KLO07507.1 - 1.5e-38 132.4 0.5 7.1e-34 117.0 0.1 2.2 2 0 0 2 2 2 2 Cell division control protein 14, SIN component FAA_hydrolase PF01557.13 KLO07508.1 - 1.3e-58 197.9 0.0 1.8e-58 197.5 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family FAA_hydrolase PF01557.13 KLO07509.1 - 3.3e-56 190.1 0.0 4.7e-56 189.6 0.0 1.2 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family Aldedh PF00171.17 KLO07510.1 - 3.4e-161 536.6 0.5 3.8e-161 536.5 0.3 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF969 PF06149.7 KLO07512.1 - 0.35 10.0 6.5 0.099 11.8 2.4 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF969) DUF2809 PF10990.3 KLO07512.1 - 3.1 8.2 5.7 18 5.8 0.7 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2809) Ytp1 PF10355.4 KLO07515.1 - 2.6e-91 305.5 10.0 4.2e-91 304.8 6.9 1.3 1 0 0 1 1 1 1 Protein of unknown function (Ytp1) DUF2427 PF10348.4 KLO07515.1 - 7.1e-17 60.9 2.5 7.1e-17 60.9 1.8 2.6 3 0 0 3 3 3 1 Domain of unknown function (DUF2427) UbiA PF01040.13 KLO07516.1 - 3.3e-37 128.1 21.8 4.4e-37 127.6 15.1 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family Rho_GDI PF02115.12 KLO07517.1 - 9.8e-49 165.4 0.0 1.2e-48 165.2 0.0 1.0 1 0 0 1 1 1 1 RHO protein GDP dissociation inhibitor Tropomyosin_1 PF12718.2 KLO07518.1 - 0.053 13.3 6.3 0.11 12.2 4.4 1.5 1 0 0 1 1 1 0 Tropomyosin like zf-CCCH PF00642.19 KLO07518.1 - 0.059 13.0 20.3 0.18 11.5 1.0 3.7 3 1 1 4 4 4 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Tropomyosin PF00261.15 KLO07518.1 - 0.36 9.8 6.8 0.95 8.5 4.7 1.6 1 1 0 1 1 1 0 Tropomyosin Pkinase PF00069.20 KLO07521.1 - 1.3e-40 139.1 0.0 1.7e-40 138.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KLO07521.1 - 1.7e-36 125.6 0.0 2e-36 125.3 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KLO07521.1 - 2.3e-07 30.1 0.0 3.9e-07 29.3 0.0 1.3 1 1 0 1 1 1 1 Kinase-like RIO1 PF01163.17 KLO07521.1 - 0.0048 16.2 0.0 0.0071 15.7 0.0 1.2 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.9 KLO07521.1 - 0.03 13.3 0.0 0.047 12.7 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KLO07521.1 - 0.083 12.6 0.0 0.11 12.1 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family G-alpha PF00503.15 KLO07523.1 - 2.4e-122 408.3 0.0 3.5e-122 407.8 0.0 1.2 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 KLO07523.1 - 2.1e-11 43.3 0.3 3.4e-07 29.6 0.0 2.3 2 0 0 2 2 2 2 ADP-ribosylation factor family AAA_29 PF13555.1 KLO07523.1 - 0.006 16.0 0.0 0.015 14.7 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain DUF815 PF05673.8 KLO07523.1 - 0.014 14.3 0.1 0.022 13.6 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_22 PF13401.1 KLO07523.1 - 0.032 14.3 0.0 0.096 12.8 0.0 1.8 1 0 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.13 KLO07523.1 - 0.038 13.4 0.0 0.073 12.5 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family DAP3 PF10236.4 KLO07523.1 - 0.063 12.1 0.1 0.098 11.5 0.1 1.2 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 Zn_clus PF00172.13 KLO07526.1 - 2.1e-07 30.7 5.0 4.8e-07 29.5 3.5 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF3365 PF11845.3 KLO07526.1 - 0.061 13.1 0.7 0.13 12.1 0.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3365) OPT PF03169.10 KLO07527.1 - 1.2e-184 615.2 65.0 1.4e-184 615.0 45.1 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein DUF2077 PF09850.4 KLO07527.1 - 0.086 12.2 3.4 2.4 7.5 0.5 2.8 2 1 1 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2077) DUF987 PF06174.6 KLO07528.1 - 0.12 11.8 0.0 0.26 10.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF987) Peptidase_M17 PF00883.16 KLO07529.1 - 1.1e-113 379.2 0.0 3.3e-113 377.6 0.0 1.7 1 1 0 1 1 1 1 Cytosol aminopeptidase family, catalytic domain F-box-like PF12937.2 KLO07530.1 - 0.001 18.7 0.4 0.0026 17.4 0.1 1.9 2 0 0 2 2 2 1 F-box-like Peptidase_C48 PF02902.14 KLO07532.1 - 1.7e-10 40.8 0.0 3.7e-10 39.7 0.0 1.5 1 1 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain peroxidase PF00141.18 KLO07533.1 - 1.2e-24 87.0 0.0 1.7e-24 86.6 0.0 1.3 1 0 0 1 1 1 1 Peroxidase RNR_inhib PF08591.5 KLO07534.1 - 8.7e-05 23.3 2.7 0.00016 22.5 0.2 2.2 2 1 0 2 2 2 1 Ribonucleotide reductase inhibitor Ribosomal_L29 PF00831.18 KLO07536.1 - 3.3e-20 71.5 3.8 3.3e-20 71.5 2.6 2.2 2 1 0 2 2 2 1 Ribosomal L29 protein UNC119_bdg PF15435.1 KLO07536.1 - 0.092 12.0 1.3 0.1 11.9 0.9 1.1 1 0 0 1 1 1 0 UNC119-binding protein C5orf30 homologue DUF607 PF04678.8 KLO07536.1 - 2.7 7.8 6.7 5.1 6.9 1.1 2.0 1 1 1 2 2 2 0 Protein of unknown function, DUF607 PGC7_Stella PF15549.1 KLO07536.1 - 3.7 7.5 6.4 4.9 7.1 4.4 1.3 1 0 0 1 1 1 0 PGC7/Stella/Dppa3 domain zf-H2C2_2 PF13465.1 KLO07538.1 - 7.2e-10 38.6 12.5 2.1e-06 27.7 0.7 2.9 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2 PF00096.21 KLO07538.1 - 2.4e-06 27.5 16.5 0.00011 22.3 0.6 3.6 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KLO07538.1 - 0.00076 19.6 15.1 0.0043 17.2 0.5 3.8 3 0 0 3 3 3 2 C2H2-type zinc finger Terminase_GpA PF05876.7 KLO07538.1 - 0.022 13.1 1.7 0.034 12.5 1.1 1.1 1 0 0 1 1 1 0 Phage terminase large subunit (GpA) zf-CHCC PF10276.4 KLO07538.1 - 0.25 11.1 3.0 3.2 7.6 0.2 2.6 2 0 0 2 2 2 0 Zinc-finger domain Cid2 PF09774.4 KLO07539.1 - 4.8e-28 98.1 4.7 1e-27 97.0 3.2 1.5 1 1 0 1 1 1 1 Caffeine-induced death protein 2 Cep57_MT_bd PF06657.8 KLO07539.1 - 0.012 15.5 0.9 0.17 11.8 0.2 2.5 2 1 1 3 3 3 0 Centrosome microtubule-binding domain of Cep57 GILT PF03227.11 KLO07540.1 - 8.3e-10 38.5 0.2 8.3e-10 38.5 0.1 1.5 2 0 0 2 2 2 1 Gamma interferon inducible lysosomal thiol reductase (GILT) RRN3 PF05327.6 KLO07541.1 - 6e-158 526.4 0.1 1.3e-157 525.3 0.0 1.5 1 1 1 2 2 2 1 RNA polymerase I specific transcription initiation factor RRN3 Y_phosphatase3 PF13350.1 KLO07542.1 - 1.7e-42 145.4 0.0 6.6e-42 143.5 0.0 1.8 2 0 0 2 2 2 1 Tyrosine phosphatase family Y_phosphatase3C PF13348.1 KLO07542.1 - 9.6e-13 48.0 0.3 3.2e-12 46.3 0.1 2.0 2 0 0 2 2 2 1 Tyrosine phosphatase family C-terminal region DSPc PF00782.15 KLO07542.1 - 0.00028 20.4 1.1 0.0018 17.8 0.1 2.5 2 1 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Y_phosphatase2 PF03162.8 KLO07542.1 - 0.0027 17.0 0.1 0.014 14.7 0.0 1.9 1 1 1 2 2 2 1 Tyrosine phosphatase family Y_phosphatase PF00102.22 KLO07542.1 - 0.078 12.3 0.0 0.1 11.9 0.0 1.3 1 0 0 1 1 1 0 Protein-tyrosine phosphatase Vac14_Fig4_bd PF11916.3 KLO07543.1 - 3.3e-76 254.4 9.0 5.6e-76 253.7 6.3 1.4 1 0 0 1 1 1 1 Vacuolar protein 14 C-terminal Fig4p binding Vac14_Fab1_bd PF12755.2 KLO07543.1 - 5.9e-39 132.3 0.0 6.7e-38 128.9 0.0 2.7 3 0 0 3 3 3 1 Vacuolar 14 Fab1-binding region HEAT PF02985.17 KLO07543.1 - 6.9e-08 31.9 0.3 0.00059 19.6 0.0 5.6 6 0 0 6 6 6 1 HEAT repeat CLASP_N PF12348.3 KLO07543.1 - 0.00014 21.3 0.1 0.12 11.7 0.0 3.3 4 0 0 4 4 4 2 CLASP N terminal HEAT_EZ PF13513.1 KLO07543.1 - 0.00095 19.5 0.0 15 6.1 0.0 5.3 4 1 1 5 5 5 1 HEAT-like repeat Cnd1 PF12717.2 KLO07543.1 - 0.0031 17.4 0.8 2.7 7.8 0.0 2.8 2 0 0 2 2 2 2 non-SMC mitotic condensation complex subunit 1 DUF1546 PF07571.8 KLO07543.1 - 0.015 15.4 0.0 0.15 12.1 0.0 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1546) RecO_C PF02565.10 KLO07543.1 - 0.017 15.0 0.1 9.3 6.1 0.0 2.9 2 0 0 2 2 2 0 Recombination protein O C terminal DUF2107 PF09880.4 KLO07543.1 - 0.15 11.9 0.4 0.31 10.9 0.3 1.4 1 0 0 1 1 1 0 Predicted membrane protein (DUF2107) GFO_IDH_MocA PF01408.17 KLO07546.1 - 6.7e-18 65.3 0.0 1.1e-17 64.6 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold EBP PF05241.7 KLO07547.1 - 2e-10 40.0 2.2 2.5e-10 39.6 1.5 1.1 1 0 0 1 1 1 1 Emopamil binding protein TMC PF07810.8 KLO07547.1 - 0.12 12.7 1.3 0.39 11.1 0.0 2.0 1 1 1 2 2 2 0 TMC domain CcmD PF04995.9 KLO07549.1 - 0.023 14.4 0.1 0.043 13.5 0.1 1.4 1 0 0 1 1 1 0 Heme exporter protein D (CcmD) PMP1_2 PF08114.6 KLO07549.1 - 0.096 12.1 0.2 0.16 11.4 0.1 1.3 1 0 0 1 1 1 0 ATPase proteolipid family DUF4202 PF13875.1 KLO07550.1 - 0.038 13.6 0.0 0.072 12.7 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4202) Acetyltransf_1 PF00583.19 KLO07551.1 - 5.8e-12 45.4 0.0 9.5e-12 44.7 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 KLO07551.1 - 1e-11 44.8 0.1 1.4e-11 44.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 KLO07551.1 - 0.0004 20.5 0.0 0.00059 20.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 KLO07551.1 - 0.00041 20.2 0.0 0.00047 20.0 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 KLO07551.1 - 0.0019 18.3 0.0 0.0025 17.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 KLO07551.1 - 0.05 13.3 0.0 0.086 12.6 0.0 1.3 1 0 0 1 1 1 0 FR47-like protein Acetyltransf_4 PF13420.1 KLO07551.1 - 0.11 12.5 0.0 0.14 12.1 0.0 1.1 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Mo25 PF08569.6 KLO07552.1 - 7.2e-125 416.4 5.5 8e-125 416.3 3.8 1.0 1 0 0 1 1 1 1 Mo25-like RepA_N PF06970.6 KLO07552.1 - 0.026 14.2 0.7 0.092 12.5 0.5 2.0 1 0 0 1 1 1 0 Replication initiator protein A (RepA) N-terminus HEAT_2 PF13646.1 KLO07552.1 - 0.049 13.9 0.0 0.49 10.6 0.0 2.4 2 0 0 2 2 2 0 HEAT repeats ATG27 PF09451.5 KLO07553.1 - 4.8e-13 48.9 0.0 2.1e-12 46.8 0.0 2.0 1 1 0 2 2 2 1 Autophagy-related protein 27 CIMR PF00878.13 KLO07553.1 - 0.038 13.7 0.1 0.11 12.3 0.1 1.7 2 0 0 2 2 2 0 Cation-independent mannose-6-phosphate receptor repeat VOMI PF03762.12 KLO07553.1 - 0.07 13.0 0.1 0.2 11.5 0.0 1.8 2 0 0 2 2 2 0 Vitelline membrane outer layer protein I (VOMI) adh_short PF00106.20 KLO07554.1 - 1e-23 84.0 0.1 1.4e-23 83.5 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KLO07554.1 - 4.4e-11 42.7 0.1 6.5e-11 42.2 0.1 1.2 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 KLO07554.1 - 1.1e-07 31.8 0.0 1.7e-07 31.2 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 KLO07554.1 - 1.4e-05 25.1 0.0 2.6e-05 24.3 0.0 1.4 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 KLO07554.1 - 0.00014 21.3 0.0 0.00022 20.7 0.0 1.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Saccharop_dh PF03435.13 KLO07554.1 - 0.003 16.5 0.0 0.0045 16.0 0.0 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase Shikimate_DH PF01488.15 KLO07554.1 - 0.008 16.2 0.1 0.016 15.3 0.1 1.4 1 1 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Polysacc_synt_2 PF02719.10 KLO07554.1 - 0.018 13.9 0.0 0.026 13.4 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein HHH PF00633.18 KLO07554.1 - 0.023 14.3 0.6 1.2 8.9 0.1 2.6 2 0 0 2 2 2 0 Helix-hairpin-helix motif TIR-like PF10137.4 KLO07554.1 - 0.026 14.1 0.0 0.051 13.1 0.0 1.5 1 0 0 1 1 1 0 Predicted nucleotide-binding protein containing TIR-like domain NmrA PF05368.8 KLO07554.1 - 0.1 11.8 0.0 0.15 11.2 0.0 1.2 1 0 0 1 1 1 0 NmrA-like family Eno-Rase_NADH_b PF12242.3 KLO07554.1 - 0.14 11.9 0.1 0.34 10.7 0.0 1.6 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase DUF1776 PF08643.5 KLO07554.1 - 0.15 11.2 0.0 2.3 7.2 0.0 2.3 2 1 0 2 2 2 0 Fungal family of unknown function (DUF1776) zf-C3HC4_3 PF13920.1 KLO07556.1 - 2.7e-09 36.5 5.4 6.2e-09 35.3 3.7 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KLO07556.1 - 5.7e-08 32.3 8.3 1.1e-07 31.4 5.7 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.1 KLO07556.1 - 6.4e-08 32.2 9.5 1.4e-07 31.1 6.6 1.6 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.1 KLO07556.1 - 2e-06 27.4 4.7 4.2e-06 26.3 3.3 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.1 KLO07556.1 - 5.5e-06 26.3 8.8 1.2e-05 25.2 6.1 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KLO07556.1 - 2.1e-05 24.0 8.6 4.6e-05 22.9 6.0 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.1 KLO07556.1 - 6.5e-05 22.4 5.1 0.00013 21.4 3.5 1.6 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-C3HC4_4 PF15227.1 KLO07556.1 - 0.00026 20.7 7.3 0.0014 18.4 5.1 2.2 1 1 0 1 1 1 1 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.1 KLO07556.1 - 0.0023 17.4 5.5 0.0047 16.4 3.8 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 FYVE PF01363.16 KLO07556.1 - 0.004 17.0 5.0 0.077 12.8 1.3 2.5 1 1 1 2 2 2 1 FYVE zinc finger Rtf2 PF04641.7 KLO07556.1 - 0.005 16.0 0.1 0.0073 15.5 0.1 1.3 1 0 0 1 1 1 1 Rtf2 RING-finger zf-RING_6 PF14835.1 KLO07556.1 - 0.02 14.6 0.9 0.02 14.6 0.6 1.7 2 0 0 2 2 2 0 zf-RING of BARD1-type protein Baculo_IE-1 PF05290.6 KLO07556.1 - 0.042 13.5 1.2 0.09 12.5 0.8 1.5 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) DUF1272 PF06906.6 KLO07556.1 - 0.22 11.4 2.9 0.45 10.3 2.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) Laminin_EGF PF00053.19 KLO07556.1 - 0.26 11.2 4.1 4.7 7.2 0.1 2.5 1 1 1 2 2 2 0 Laminin EGF-like (Domains III and V) zf-rbx1 PF12678.2 KLO07556.1 - 0.33 11.0 6.5 0.82 9.8 4.5 1.7 1 0 0 1 1 1 0 RING-H2 zinc finger zf-MIZ PF02891.15 KLO07556.1 - 2.2 7.8 7.2 5.2 6.6 5.0 1.7 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger Acyltransferase PF01553.16 KLO07559.1 - 1.3e-15 56.9 0.0 2.1e-15 56.3 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase Ribosomal_S11 PF00411.14 KLO07561.1 - 4.1e-41 139.6 0.3 5e-41 139.3 0.2 1.1 1 0 0 1 1 1 1 Ribosomal protein S11 HTH_19 PF12844.2 KLO07562.1 - 4.3e-09 36.2 0.0 4.9e-09 36.1 0.0 1.0 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_3 PF01381.17 KLO07562.1 - 5.6e-09 35.7 0.0 6.8e-09 35.4 0.0 1.1 1 0 0 1 1 1 1 Helix-turn-helix HTH_31 PF13560.1 KLO07562.1 - 2.2e-06 27.7 0.0 2.7e-06 27.4 0.0 1.1 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_26 PF13443.1 KLO07562.1 - 1.4e-05 25.1 0.0 1.7e-05 24.8 0.0 1.1 1 0 0 1 1 1 1 Cro/C1-type HTH DNA-binding domain HTH_28 PF13518.1 KLO07562.1 - 0.1 12.6 0.0 0.16 12.0 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_20 PF12840.2 KLO07562.1 - 0.14 11.9 0.0 0.22 11.3 0.0 1.2 1 0 0 1 1 1 0 Helix-turn-helix domain PMD PF10536.4 KLO07563.1 - 0.073 12.0 0.3 0.11 11.5 0.2 1.2 1 0 0 1 1 1 0 Plant mobile domain ABC1 PF03109.11 KLO07564.1 - 8.7e-27 93.4 0.5 2e-26 92.2 0.1 1.9 2 0 0 2 2 2 1 ABC1 family zf-C3HC4_3 PF13920.1 KLO07565.1 - 2.6e-07 30.2 8.6 4.8e-07 29.3 6.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KLO07565.1 - 3.1e-05 23.9 12.3 5.5e-05 23.0 8.5 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KLO07565.1 - 3.4e-05 23.5 11.8 5.6e-05 22.8 7.6 1.8 2 0 0 2 2 2 1 Ring finger domain zf-RING_5 PF14634.1 KLO07565.1 - 0.00011 21.8 9.9 0.00018 21.1 6.9 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.20 KLO07565.1 - 0.00013 21.5 10.9 0.00022 20.8 7.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) FYVE PF01363.16 KLO07565.1 - 0.00063 19.5 5.5 0.003 17.4 3.9 2.0 1 1 1 2 2 2 1 FYVE zinc finger zf-RING_UBOX PF13445.1 KLO07565.1 - 0.0023 17.5 7.8 0.0052 16.4 5.4 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_4 PF14570.1 KLO07565.1 - 0.0032 17.0 8.9 0.0056 16.2 6.2 1.4 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain Rtf2 PF04641.7 KLO07565.1 - 0.69 9.0 2.8 0.35 10.0 0.3 1.7 2 0 0 2 2 2 0 Rtf2 RING-finger Baculo_IE-1 PF05290.6 KLO07565.1 - 1.9 8.2 3.6 3.6 7.3 2.5 1.4 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) C1_3 PF07649.7 KLO07565.1 - 2.1 8.4 6.9 4.2 7.4 4.8 1.5 1 0 0 1 1 1 0 C1-like domain zf-C3HC4_4 PF15227.1 KLO07565.1 - 4.1 7.3 12.3 7.5 6.5 8.5 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Peptidase_C48 PF02902.14 KLO07566.1 - 3.6e-05 23.5 1.4 6.1e-05 22.7 1.0 1.3 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain CENP-B_dimeris PF09026.5 KLO07569.1 - 3.7 7.8 8.6 0.75 10.0 2.8 2.0 2 0 0 2 2 2 0 Centromere protein B dimerisation domain ubiquitin PF00240.18 KLO07570.1 - 8.6e-263 848.3 55.6 1.2e-32 111.1 0.7 8.0 8 0 0 8 8 8 8 Ubiquitin family Rad60-SLD PF11976.3 KLO07570.1 - 2.4e-147 478.8 51.5 2.5e-18 65.5 0.7 8.0 8 0 0 8 8 8 8 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 KLO07570.1 - 1.7e-43 146.7 30.4 0.00014 22.0 0.2 10.2 8 8 0 8 8 8 8 Ubiquitin-like domain Telomere_Sde2 PF13019.1 KLO07570.1 - 4.3e-42 143.5 6.6 0.0018 17.9 0.0 8.1 8 0 0 8 8 8 8 Telomere stability and silencing DUF2407 PF10302.4 KLO07570.1 - 1.6e-24 85.8 12.5 0.21 11.7 0.0 8.2 1 1 2 8 8 8 8 DUF2407 ubiquitin-like domain Rad60-SLD_2 PF13881.1 KLO07570.1 - 7.6e-19 67.6 16.1 0.48 10.3 0.0 9.0 8 0 0 8 8 8 8 Ubiquitin-2 like Rad60 SUMO-like DUF2870 PF11069.3 KLO07570.1 - 9.8e-19 67.2 0.0 4.6 7.3 0.0 8.8 8 0 0 8 8 8 8 Protein of unknown function (DUF2870) TUG-UBL1 PF11470.3 KLO07570.1 - 1.1e-09 38.1 18.8 0.87 9.5 0.0 8.2 8 0 0 8 8 8 2 GLUT4 regulating protein TUG Plexin_cytopl PF08337.7 KLO07570.1 - 2.9e-09 35.7 15.0 1.8 6.8 0.1 8.7 8 0 0 8 8 8 7 Plexin cytoplasmic RasGAP domain Big_3_3 PF13750.1 KLO07570.1 - 1.2e-06 28.0 1.8 26 4.2 0.0 7.0 7 1 1 8 8 8 0 Bacterial Ig-like domain (group 3) FlgD_ig PF13860.1 KLO07570.1 - 1.2e-06 28.1 17.1 9 6.1 0.0 8.1 8 0 0 8 8 8 1 FlgD Ig-like domain ACT_4 PF13291.1 KLO07570.1 - 1.5e-05 25.2 7.4 44 4.5 0.0 7.8 8 0 0 8 8 8 0 ACT domain DUF3861 PF12977.2 KLO07570.1 - 2e-05 24.6 17.1 14 5.8 0.0 8.2 8 0 0 8 8 8 0 Domain of Unknown Function with PDB structure (DUF3861) GABP-alpha PF11620.3 KLO07570.1 - 0.00044 20.1 24.0 26 4.8 0.0 7.9 8 0 0 8 8 8 0 GA-binding protein alpha chain FERM_N PF09379.5 KLO07570.1 - 0.011 15.8 17.9 51 4.0 0.0 8.7 8 0 0 8 8 8 0 FERM N-terminal domain Tash_PEST PF07708.6 KLO07570.1 - 0.084 12.8 65.4 1.1 9.3 1.3 8.4 8 0 0 8 8 8 0 Tash protein PEST motif CAP PF00188.21 KLO07573.1 - 1.2e-22 80.6 2.1 1.5e-22 80.4 1.4 1.1 1 0 0 1 1 1 1 Cysteine-rich secretory protein family EMA PF02488.10 KLO07573.1 - 0.018 14.5 0.0 0.025 14.0 0.0 1.1 1 0 0 1 1 1 0 Merozoite Antigen DUF1793 PF08760.6 KLO07574.1 - 9.6e-58 194.8 0.1 2e-57 193.8 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1793) DUF2012 PF09430.5 KLO07575.1 - 1.4e-24 86.2 0.0 2e-24 85.8 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2012) DUF4480 PF13715.1 KLO07575.1 - 0.056 13.4 0.0 0.088 12.8 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4480) fn3_3 PF14686.1 KLO07575.1 - 0.098 12.7 0.0 0.19 11.8 0.0 1.5 1 0 0 1 1 1 0 Polysaccharide lyase family 4, domain II zf-H2C2_2 PF13465.1 KLO07576.1 - 2.1e-09 37.1 1.9 8.5e-08 32.1 0.3 2.6 2 0 0 2 2 2 1 Zinc-finger double domain zf-C2H2 PF00096.21 KLO07576.1 - 1.9e-06 27.8 8.6 0.0015 18.7 1.4 2.5 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KLO07576.1 - 0.0001 22.3 6.9 0.12 12.7 0.7 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger Ogr_Delta PF04606.7 KLO07576.1 - 0.045 13.4 0.3 11 5.7 0.1 2.5 2 0 0 2 2 2 0 Ogr/Delta-like zinc finger zf-C2H2_6 PF13912.1 KLO07576.1 - 0.13 12.2 1.8 0.14 12.0 0.1 2.0 2 0 0 2 2 2 0 C2H2-type zinc finger S1FA PF04689.8 KLO07576.1 - 0.34 10.8 1.2 0.59 10.0 0.8 1.3 1 0 0 1 1 1 0 DNA binding protein S1FA DUF2348 PF09807.4 KLO07577.1 - 3.3e-15 55.8 0.0 4.2e-15 55.5 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2348) AAA PF00004.24 KLO07577.1 - 0.0042 17.2 0.0 0.0096 16.1 0.0 1.6 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) LcrR PF09621.5 KLO07577.1 - 0.038 13.2 0.0 0.066 12.4 0.0 1.3 1 0 0 1 1 1 0 Type III secretion system regulator (LcrR) Elong_Iki1 PF10483.4 KLO07577.1 - 0.093 12.0 0.0 0.21 10.9 0.0 1.7 1 1 0 1 1 1 0 Elongator subunit Iki1 Myb_Cef PF11831.3 KLO07578.1 - 7.5e-64 215.1 5.8 7.5e-64 215.1 4.0 4.7 5 0 0 5 5 5 1 pre-mRNA splicing factor component Myb_DNA-binding PF00249.26 KLO07578.1 - 4.6e-20 71.4 7.6 8.2e-11 41.7 0.4 3.0 3 0 0 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 KLO07578.1 - 1.7e-17 63.2 7.9 3.1e-12 46.4 2.3 3.5 2 1 1 3 3 3 2 Myb-like DNA-binding domain Abhydrolase_6 PF12697.2 KLO07579.1 - 1.2e-28 100.5 0.0 2.7e-28 99.4 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KLO07579.1 - 2.6e-13 49.9 0.0 1.1e-12 47.9 0.0 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KLO07579.1 - 7.9e-13 48.4 0.0 1.9e-12 47.2 0.0 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.3 KLO07579.1 - 4.3e-06 26.4 0.0 8.2e-06 25.5 0.0 1.4 1 0 0 1 1 1 1 Putative lysophospholipase AXE1 PF05448.7 KLO07579.1 - 0.0012 17.4 0.1 0.13 10.7 0.0 2.2 2 0 0 2 2 2 2 Acetyl xylan esterase (AXE1) Chlorophyllase PF07224.6 KLO07579.1 - 0.0095 14.7 0.0 0.015 14.1 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase DLH PF01738.13 KLO07579.1 - 0.085 12.1 0.0 0.17 11.1 0.0 1.5 1 0 0 1 1 1 0 Dienelactone hydrolase family FSH1 PF03959.8 KLO07579.1 - 0.11 11.9 0.0 2.1 7.7 0.0 2.4 2 0 0 2 2 2 0 Serine hydrolase (FSH1) Chlorophyllase2 PF12740.2 KLO07579.1 - 0.11 11.3 0.0 0.16 10.8 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase enzyme Abhydrolase_6 PF12697.2 KLO07580.1 - 3.4e-22 79.4 0.0 4.9e-22 78.9 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KLO07580.1 - 5.6e-11 42.3 0.0 1.1e-10 41.4 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KLO07580.1 - 8.3e-11 41.8 0.0 6e-10 39.0 0.0 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.3 KLO07580.1 - 0.0028 17.4 0.0 0.0051 16.6 0.0 1.4 1 0 0 1 1 1 1 Putative lysophospholipase AXE1 PF05448.7 KLO07580.1 - 0.0046 15.5 0.1 0.97 7.8 0.0 2.1 2 0 0 2 2 2 2 Acetyl xylan esterase (AXE1) DUF2346 PF09803.4 KLO07580.1 - 0.079 12.8 0.1 21 5.0 0.0 2.5 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2346) FAD_binding_6 PF00970.19 KLO07581.1 - 5.5e-32 109.8 0.0 1.1e-31 108.8 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.16 KLO07581.1 - 6.6e-30 103.8 0.0 1.1e-29 103.2 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.7 KLO07581.1 - 7.2e-06 25.9 0.0 0.00018 21.4 0.0 2.2 1 1 1 2 2 2 1 Ferric reductase NAD binding domain FAD_binding_9 PF08021.6 KLO07581.1 - 0.00033 20.5 0.0 0.00077 19.4 0.0 1.6 2 0 0 2 2 2 1 Siderophore-interacting FAD-binding domain GST_N_3 PF13417.1 KLO07582.1 - 2.9e-07 30.6 0.0 1.2e-06 28.6 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain Fcf1 PF04900.7 KLO07582.1 - 0.0048 16.9 0.0 0.0082 16.2 0.0 1.3 1 0 0 1 1 1 1 Fcf1 GST_C_2 PF13410.1 KLO07582.1 - 0.0079 16.0 0.0 0.015 15.1 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 KLO07582.1 - 0.13 12.3 0.0 0.21 11.6 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain Trs65 PF12735.2 KLO07583.1 - 1.7e-21 76.8 0.0 2.1e-19 69.9 0.0 2.7 2 0 0 2 2 2 2 TRAPP trafficking subunit Trs65 WD40 PF00400.27 KLO07585.1 - 3e-06 26.8 12.7 6.5e-05 22.6 0.1 6.0 7 0 0 7 7 7 1 WD domain, G-beta repeat eIF2A PF08662.6 KLO07585.1 - 1.2e-05 25.1 0.0 1.3 8.6 0.0 4.5 3 1 2 5 5 5 3 Eukaryotic translation initiation factor eIF2A IKI3 PF04762.7 KLO07585.1 - 0.013 13.3 0.0 0.31 8.8 0.0 2.7 3 1 0 3 3 3 0 IKI3 family PD40 PF07676.7 KLO07585.1 - 0.6 9.8 3.2 18 5.1 0.0 3.5 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat MFS_1 PF07690.11 KLO07586.1 - 8.7e-41 139.7 39.5 1.9e-40 138.6 23.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 KLO07586.1 - 1e-12 47.0 1.4 1.8e-12 46.2 0.9 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 KLO07586.1 - 1.3e-12 47.0 22.8 2.6e-12 46.0 15.8 1.5 1 1 0 1 1 1 1 Sugar (and other) transporter Pyr_redox_3 PF13738.1 KLO07587.1 - 2.2e-20 73.6 0.1 1.2e-18 67.8 0.1 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 KLO07587.1 - 1.1e-13 50.3 0.4 9.3e-06 24.1 0.0 3.0 2 2 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.9 KLO07587.1 - 5.3e-13 49.3 0.7 3.9e-06 26.9 0.0 2.9 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 KLO07587.1 - 3.9e-09 35.8 0.7 1e-05 24.6 0.0 3.2 3 0 0 3 3 3 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KLO07587.1 - 1.3e-08 34.7 0.5 2.3e-06 27.5 0.0 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 KLO07587.1 - 2.3e-08 33.9 2.2 0.0077 16.0 0.0 4.1 4 0 0 4 4 4 2 FAD-NAD(P)-binding FAD_binding_2 PF00890.19 KLO07587.1 - 5.7e-06 25.4 1.4 0.058 12.2 0.1 3.1 3 0 0 3 3 3 2 FAD binding domain Pyr_redox PF00070.22 KLO07587.1 - 2.3e-05 24.6 4.1 0.027 14.8 0.0 3.6 4 0 0 4 4 4 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 KLO07587.1 - 4.3e-05 22.5 3.0 0.18 10.6 0.0 3.6 3 1 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Shikimate_DH PF01488.15 KLO07587.1 - 0.00014 22.0 0.1 0.025 14.6 0.0 3.1 3 0 0 3 3 3 1 Shikimate / quinate 5-dehydrogenase FAD_oxidored PF12831.2 KLO07587.1 - 0.00021 20.5 0.0 0.012 14.6 0.0 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase 3HCDH_N PF02737.13 KLO07587.1 - 0.00021 21.0 0.7 0.0028 17.3 0.1 2.2 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain HI0933_like PF03486.9 KLO07587.1 - 0.00029 19.4 3.5 0.072 11.5 0.2 2.9 3 0 0 3 3 3 2 HI0933-like protein GIDA PF01134.17 KLO07587.1 - 0.00041 19.3 2.0 0.12 11.1 0.2 3.0 3 0 0 3 3 3 2 Glucose inhibited division protein A Thi4 PF01946.12 KLO07587.1 - 0.00065 18.8 0.5 0.24 10.4 0.0 2.5 3 0 0 3 3 3 2 Thi4 family Amino_oxidase PF01593.19 KLO07587.1 - 0.0027 16.8 0.3 0.031 13.3 0.0 2.5 2 1 1 3 3 3 1 Flavin containing amine oxidoreductase 2-Hacid_dh_C PF02826.14 KLO07587.1 - 0.024 13.7 0.0 0.46 9.6 0.0 2.4 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Lycopene_cycl PF05834.7 KLO07587.1 - 0.1 11.4 0.0 7.7 5.3 0.0 2.9 3 0 0 3 3 3 0 Lycopene cyclase protein PP2C PF00481.16 KLO07588.1 - 2.1e-35 122.3 0.0 5.8e-34 117.6 0.0 2.1 1 1 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.1 KLO07588.1 - 0.00031 20.2 0.0 0.00073 18.9 0.0 1.4 1 1 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.7 KLO07588.1 - 0.0053 16.4 0.1 0.018 14.7 0.0 1.8 2 0 0 2 2 2 1 Stage II sporulation protein E (SpoIIE) 2-Hacid_dh_C PF02826.14 KLO07589.1 - 4.8e-54 182.2 0.0 1.1e-53 181.0 0.0 1.5 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 KLO07589.1 - 3.8e-10 39.3 0.7 7.3e-10 38.4 0.1 1.6 2 1 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 KLO07589.1 - 0.00069 19.4 0.0 0.012 15.5 0.0 2.1 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase PaRep2a PF07903.6 KLO07589.1 - 0.046 13.3 0.0 0.082 12.5 0.0 1.3 1 0 0 1 1 1 0 PaRep2a protein ADH_zinc_N PF00107.21 KLO07589.1 - 0.12 11.9 0.0 0.24 10.9 0.0 1.5 1 0 0 1 1 1 0 Zinc-binding dehydrogenase His_Phos_2 PF00328.17 KLO07590.1 - 2e-45 155.6 0.0 2.4e-45 155.3 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Git3 PF11710.3 KLO07591.1 - 0.0021 17.6 11.4 0.0021 17.6 7.9 2.2 2 1 0 2 2 2 1 G protein-coupled glucose receptor regulating Gpa2 Luteo_Vpg PF01659.11 KLO07591.1 - 0.0044 16.6 0.3 0.0084 15.7 0.2 1.4 1 0 0 1 1 1 1 Luteovirus putative VPg genome linked protein Dicty_CAR PF05462.6 KLO07591.1 - 0.015 14.2 6.8 0.028 13.3 4.7 1.4 1 0 0 1 1 1 0 Slime mold cyclic AMP receptor Herpes_VP19C PF03327.9 KLO07593.1 - 0.062 12.1 0.0 0.11 11.4 0.0 1.3 1 0 0 1 1 1 0 Herpesvirus capsid shell protein VP19C Mito_fiss_reg PF05308.6 KLO07593.1 - 2.5 7.4 8.6 5.7 6.2 5.9 1.5 1 0 0 1 1 1 0 Mitochondrial fission regulator NACHT PF05729.7 KLO07595.1 - 6.1e-12 45.5 0.1 1.2e-10 41.3 0.0 2.4 2 0 0 2 2 2 1 NACHT domain AAA_22 PF13401.1 KLO07595.1 - 1.1e-07 32.0 0.0 0.00017 21.7 0.0 2.9 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.1 KLO07595.1 - 5e-06 26.6 0.4 0.018 15.0 0.0 4.0 4 1 0 4 4 3 1 AAA ATPase domain Parvo_NS1 PF01057.12 KLO07595.1 - 1.3e-05 24.2 1.0 0.035 12.9 0.0 2.3 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 AAA_30 PF13604.1 KLO07595.1 - 0.00014 21.5 0.4 0.075 12.6 0.0 2.4 2 0 0 2 2 2 2 AAA domain NB-ARC PF00931.17 KLO07595.1 - 0.00039 19.3 0.1 0.007 15.2 0.1 2.5 2 1 0 2 2 2 1 NB-ARC domain AAA PF00004.24 KLO07595.1 - 0.00086 19.5 0.0 0.036 14.2 0.0 2.9 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.1 KLO07595.1 - 0.00098 18.8 0.0 0.06 13.1 0.0 3.0 3 0 0 3 3 3 1 Part of AAA domain APS_kinase PF01583.15 KLO07595.1 - 0.0011 18.6 0.6 0.3 10.7 0.1 2.3 2 0 0 2 2 2 1 Adenylylsulphate kinase RNA_helicase PF00910.17 KLO07595.1 - 0.0017 18.4 0.2 0.48 10.6 0.0 2.7 2 0 0 2 2 2 1 RNA helicase AAA_33 PF13671.1 KLO07595.1 - 0.016 15.0 0.0 0.18 11.7 0.0 2.6 2 0 0 2 2 2 0 AAA domain PhoH PF02562.11 KLO07595.1 - 0.028 13.6 0.1 1.1 8.4 0.0 2.3 2 0 0 2 2 2 0 PhoH-like protein PIF1 PF05970.9 KLO07595.1 - 0.04 12.8 0.0 0.99 8.2 0.0 2.2 2 0 0 2 2 2 0 PIF1-like helicase Torsin PF06309.6 KLO07595.1 - 0.064 13.1 0.0 5.5 6.8 0.0 2.8 3 0 0 3 3 3 0 Torsin ATP-synt_ab PF00006.20 KLO07595.1 - 0.068 12.6 0.0 0.6 9.5 0.0 2.2 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_17 PF13207.1 KLO07595.1 - 0.077 13.8 1.0 1.2 9.9 0.6 3.0 2 1 0 2 2 2 0 AAA domain AAA_25 PF13481.1 KLO07595.1 - 0.12 11.8 0.5 0.95 8.8 0.1 2.5 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.22 KLO07595.1 - 0.12 12.6 0.0 0.52 10.6 0.0 2.1 2 0 0 2 2 1 0 ABC transporter Muted PF14942.1 KLO07606.1 - 2.9 7.7 6.9 5.6 6.8 0.2 2.8 3 0 0 3 3 3 0 Organelle biogenesis, Muted-like protein Vezatin PF12632.2 KLO07606.1 - 3.7 6.5 5.3 4.1 6.4 0.6 2.1 1 1 0 2 2 2 0 Mysoin-binding motif of peroxisomes NACHT PF05729.7 KLO07609.1 - 1.9e-12 47.1 0.0 4.1e-12 46.0 0.0 1.6 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.1 KLO07609.1 - 8.5e-07 29.1 0.0 5.8e-06 26.4 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 KLO07609.1 - 1.3e-05 25.2 0.2 8.5e-05 22.6 0.0 2.4 2 1 0 2 2 2 1 AAA ATPase domain NB-ARC PF00931.17 KLO07609.1 - 3.6e-05 22.7 0.0 7.2e-05 21.7 0.0 1.4 1 0 0 1 1 1 1 NB-ARC domain AAA PF00004.24 KLO07609.1 - 0.00066 19.8 0.1 0.004 17.3 0.0 2.2 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Parvo_NS1 PF01057.12 KLO07609.1 - 0.004 16.0 0.0 0.0067 15.3 0.0 1.3 1 0 0 1 1 1 1 Parvovirus non-structural protein NS1 RNA_helicase PF00910.17 KLO07609.1 - 0.024 14.8 0.3 0.13 12.4 0.0 2.4 3 0 0 3 3 2 0 RNA helicase AAA_30 PF13604.1 KLO07609.1 - 0.029 13.9 0.0 0.08 12.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.22 KLO07609.1 - 0.06 13.6 0.0 0.37 11.0 0.0 2.4 3 0 0 3 3 3 0 ABC transporter AAA_25 PF13481.1 KLO07609.1 - 0.061 12.7 0.1 0.3 10.4 0.0 2.2 2 0 0 2 2 2 0 AAA domain APS_kinase PF01583.15 KLO07609.1 - 0.12 11.9 0.0 0.27 10.8 0.0 1.5 1 0 0 1 1 1 0 Adenylylsulphate kinase PhoH PF02562.11 KLO07609.1 - 0.18 11.0 0.1 0.36 10.0 0.1 1.4 1 0 0 1 1 1 0 PhoH-like protein Parvo_NS1 PF01057.12 KLO07610.1 - 0.02 13.7 0.0 0.024 13.4 0.0 1.1 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Slx4 PF09494.5 KLO07610.1 - 0.031 14.0 0.1 0.13 12.0 0.0 1.9 1 1 0 1 1 1 0 Slx4 endonuclease AAA_22 PF13401.1 KLO07610.1 - 0.12 12.5 0.0 0.2 11.8 0.0 1.4 1 1 0 1 1 1 0 AAA domain FMN_bind PF04205.9 KLO07613.1 - 1.2 9.3 5.3 15 5.8 0.1 2.5 2 0 0 2 2 2 0 FMN-binding domain 3Beta_HSD PF01073.14 KLO07614.1 - 3.7e-64 216.1 0.0 1.1e-57 194.9 0.0 2.2 2 0 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 KLO07614.1 - 1.6e-35 122.6 0.0 2.3e-35 122.1 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 KLO07614.1 - 5.6e-16 59.0 0.1 9.4e-16 58.3 0.1 1.4 1 0 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 KLO07614.1 - 2.1e-14 53.0 0.0 3.7e-10 39.1 0.0 2.1 2 0 0 2 2 2 2 Male sterility protein RmlD_sub_bind PF04321.12 KLO07614.1 - 1.3e-10 40.7 0.0 2.5e-10 39.7 0.0 1.4 1 0 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.10 KLO07614.1 - 3.5e-05 22.8 0.2 0.00031 19.7 0.4 2.3 2 1 0 2 2 2 1 Polysaccharide biosynthesis protein adh_short PF00106.20 KLO07614.1 - 0.0007 19.5 2.0 0.0056 16.6 1.4 2.4 1 1 0 1 1 1 1 short chain dehydrogenase NmrA PF05368.8 KLO07614.1 - 0.0038 16.5 0.7 0.037 13.2 0.5 2.1 1 1 0 1 1 1 1 NmrA-like family KR PF08659.5 KLO07614.1 - 0.021 14.4 0.8 0.086 12.4 0.4 2.0 1 1 1 2 2 2 0 KR domain DNA_pol_B_exo1 PF03104.14 KLO07614.1 - 0.087 11.6 0.0 0.13 11.1 0.0 1.1 1 0 0 1 1 1 0 DNA polymerase family B, exonuclease domain Nbl1_Borealin_N PF10444.4 KLO07615.1 - 1.1e-09 37.5 0.1 2.3e-09 36.4 0.1 1.6 1 0 0 1 1 1 1 Nbl1 / Borealin N terminal Borealin PF10512.4 KLO07615.1 - 0.0074 16.1 4.4 0.026 14.4 0.3 3.1 3 0 0 3 3 3 1 Cell division cycle-associated protein 8 POP1 PF06978.6 KLO07616.1 - 2.6e-47 160.8 13.5 2e-44 151.4 9.4 2.4 1 1 0 1 1 1 1 Ribonucleases P/MRP protein subunit POP1 POPLD PF08170.7 KLO07616.1 - 3.6e-28 97.2 0.6 1.1e-27 95.6 0.4 1.9 1 0 0 1 1 1 1 POPLD (NUC188) domain DUF3421 PF11901.3 KLO07617.1 - 9.1e-14 51.2 0.0 1.4e-07 31.2 0.0 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF3421) MerR-DNA-bind PF09278.6 KLO07618.1 - 0.098 13.0 0.4 0.42 11.0 0.1 2.1 2 0 0 2 2 2 0 MerR, DNA binding DUF2205 PF10224.4 KLO07618.1 - 0.28 10.7 2.8 0.19 11.3 0.4 1.8 2 1 0 2 2 2 0 Predicted coiled-coil protein (DUF2205) Pkinase PF00069.20 KLO07619.1 - 7.8e-20 71.1 0.0 1.3e-19 70.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KLO07619.1 - 1.2e-05 24.5 0.0 7.1e-05 22.0 0.0 1.9 2 0 0 2 2 2 1 Protein tyrosine kinase CDC45 PF02724.9 KLO07619.1 - 0.022 12.8 6.0 0.03 12.3 4.2 1.2 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.7 KLO07619.1 - 0.026 12.4 10.5 0.037 11.9 7.3 1.1 1 0 0 1 1 1 0 Nop14-like family Nucleoplasmin PF03066.10 KLO07619.1 - 0.029 13.8 6.1 0.05 13.1 4.2 1.3 1 0 0 1 1 1 0 Nucleoplasmin SDA1 PF05285.7 KLO07619.1 - 0.041 13.1 6.8 0.068 12.4 4.7 1.3 1 0 0 1 1 1 0 SDA1 Daxx PF03344.10 KLO07619.1 - 0.11 10.9 14.2 0.18 10.2 9.8 1.3 1 0 0 1 1 1 0 Daxx Family Na_trans_assoc PF06512.8 KLO07619.1 - 0.23 11.4 5.2 0.38 10.6 3.6 1.4 1 0 0 1 1 1 0 Sodium ion transport-associated Sigma70_ner PF04546.8 KLO07619.1 - 0.87 9.1 9.7 1.6 8.3 6.7 1.3 1 0 0 1 1 1 0 Sigma-70, non-essential region Pkinase PF00069.20 KLO07620.1 - 8.8e-46 156.1 0.0 1.3e-45 155.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KLO07620.1 - 1.8e-22 79.7 0.0 6.7e-22 77.8 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KLO07620.1 - 1.9e-07 30.3 0.0 3.6e-07 29.4 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 KLO07620.1 - 0.00011 21.9 0.0 0.00025 20.8 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 KLO07620.1 - 0.11 12.0 0.0 0.25 10.8 0.0 1.5 1 0 0 1 1 1 0 Choline/ethanolamine kinase Exo_endo_phos PF03372.18 KLO07622.1 - 4.7e-09 36.5 0.1 6.9e-09 35.9 0.1 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.1 KLO07622.1 - 0.0053 16.3 0.7 0.076 12.6 0.3 2.6 2 1 0 2 2 2 1 Endonuclease-reverse transcriptase HhH-GPD PF00730.20 KLO07623.1 - 1.4e-09 38.2 0.0 2.2e-09 37.5 0.0 1.4 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein AAA_5 PF07728.9 KLO07624.1 - 7.2e-116 382.1 0.0 6.3e-28 97.2 0.0 8.8 8 0 0 8 8 8 8 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 KLO07624.1 - 6.4e-26 90.4 0.0 6.7e-08 32.2 0.0 6.2 7 0 0 7 7 5 4 ATPase family associated with various cellular activities (AAA) AAA PF00004.24 KLO07624.1 - 1.1e-21 77.4 0.0 1.8e-05 24.9 0.0 6.6 6 0 0 6 6 5 4 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 KLO07624.1 - 1.6e-21 76.8 0.0 0.0065 16.6 0.0 7.3 6 0 0 6 6 6 4 AAA domain AAA_16 PF13191.1 KLO07624.1 - 3e-21 76.2 10.9 0.00025 21.0 0.0 7.8 7 0 0 7 7 6 4 AAA ATPase domain AAA_17 PF13207.1 KLO07624.1 - 1.1e-20 74.7 0.0 0.0081 16.9 0.0 7.4 6 0 0 6 6 6 5 AAA domain AAA_18 PF13238.1 KLO07624.1 - 1.9e-18 66.9 0.0 0.055 13.7 0.0 7.0 6 0 0 6 6 6 4 AAA domain AAA_14 PF13173.1 KLO07624.1 - 4.6e-17 62.1 0.0 0.0012 18.6 0.0 7.0 7 0 0 7 7 6 4 AAA domain AAA_19 PF13245.1 KLO07624.1 - 8.2e-16 57.5 2.4 0.092 12.5 0.0 6.8 6 0 0 6 6 6 4 Part of AAA domain Sigma54_activat PF00158.21 KLO07624.1 - 9.7e-15 54.4 0.0 0.016 14.7 0.0 5.7 5 0 0 5 5 5 3 Sigma-54 interaction domain AAA_33 PF13671.1 KLO07624.1 - 1.1e-14 54.4 0.0 0.0077 16.1 0.0 6.6 6 1 0 6 6 6 4 AAA domain T2SE PF00437.15 KLO07624.1 - 3.3e-13 49.1 0.1 0.088 11.6 0.0 6.0 6 0 0 6 6 6 3 Type II/IV secretion system protein Sigma54_activ_2 PF14532.1 KLO07624.1 - 1.7e-10 41.0 0.3 0.0054 16.7 0.0 6.1 7 0 0 7 7 5 2 Sigma-54 interaction domain AAA_29 PF13555.1 KLO07624.1 - 6.7e-10 38.3 0.9 0.15 11.5 0.0 5.7 6 0 0 6 6 5 2 P-loop containing region of AAA domain ABC_tran PF00005.22 KLO07624.1 - 8.3e-09 35.8 0.3 0.56 10.4 0.0 6.0 6 0 0 6 6 5 2 ABC transporter Zeta_toxin PF06414.7 KLO07624.1 - 9.6e-09 34.6 0.0 0.93 8.5 0.0 5.4 5 0 0 5 5 5 2 Zeta toxin RNA_helicase PF00910.17 KLO07624.1 - 1.3e-08 34.9 0.0 5.8 7.1 0.0 6.2 5 0 0 5 5 5 0 RNA helicase AAA_28 PF13521.1 KLO07624.1 - 8.7e-08 32.2 2.9 1.6 8.6 0.0 7.1 7 0 0 7 7 7 1 AAA domain AAA_23 PF13476.1 KLO07624.1 - 9.7e-08 32.5 0.0 3.8 7.7 0.0 5.8 5 0 0 5 5 5 0 AAA domain NACHT PF05729.7 KLO07624.1 - 1.4e-07 31.3 0.4 0.82 9.3 0.0 5.1 4 0 0 4 4 4 1 NACHT domain MobB PF03205.9 KLO07624.1 - 6.6e-07 29.1 0.1 0.46 10.1 0.0 5.5 5 0 0 5 5 5 1 Molybdopterin guanine dinucleotide synthesis protein B Miro PF08477.8 KLO07624.1 - 7.8e-07 29.6 1.3 26 5.3 0.0 6.1 6 0 0 6 6 5 0 Miro-like protein UPF0079 PF02367.12 KLO07624.1 - 1.1e-06 28.2 0.5 1.6 8.3 0.0 5.5 6 0 0 6 6 5 1 Uncharacterised P-loop hydrolase UPF0079 IstB_IS21 PF01695.12 KLO07624.1 - 2.1e-06 27.2 0.0 0.86 8.9 0.0 4.9 5 0 0 5 5 5 1 IstB-like ATP binding protein DUF815 PF05673.8 KLO07624.1 - 3.5e-06 26.1 0.3 0.87 8.4 0.0 4.5 4 0 0 4 4 4 1 Protein of unknown function (DUF815) Mg_chelatase PF01078.16 KLO07624.1 - 3.8e-06 26.2 5.1 8.7 5.4 0.0 7.0 6 2 1 7 7 6 0 Magnesium chelatase, subunit ChlI NTPase_1 PF03266.10 KLO07624.1 - 9.2e-06 25.4 2.7 2.7 7.6 0.0 5.2 5 0 0 5 5 5 1 NTPase AAA_25 PF13481.1 KLO07624.1 - 5.1e-05 22.7 1.1 9.3 5.6 0.0 4.9 4 0 0 4 4 4 0 AAA domain AAA_11 PF13086.1 KLO07624.1 - 0.00014 21.5 0.0 1.6 8.2 0.0 4.8 5 0 0 5 5 5 1 AAA domain RuvB_N PF05496.7 KLO07624.1 - 0.00019 20.5 0.3 0.75 8.7 0.0 4.4 3 1 0 3 3 2 1 Holliday junction DNA helicase ruvB N-terminus DEAD PF00270.24 KLO07624.1 - 0.00024 20.6 0.1 3.1 7.2 0.0 4.2 4 0 0 4 4 4 1 DEAD/DEAH box helicase ResIII PF04851.10 KLO07624.1 - 0.00044 20.1 0.0 1.8 8.3 0.0 4.4 5 0 0 5 5 4 1 Type III restriction enzyme, res subunit DUF258 PF03193.11 KLO07624.1 - 0.00047 19.3 0.1 19 4.3 0.0 4.4 4 0 0 4 4 4 0 Protein of unknown function, DUF258 TIP49 PF06068.8 KLO07624.1 - 0.00066 18.5 0.4 0.082 11.6 0.0 3.7 5 0 0 5 5 5 1 TIP49 C-terminus FtsK_SpoIIIE PF01580.13 KLO07624.1 - 0.00099 18.6 1.2 1.1 8.7 0.0 4.3 5 0 0 5 5 4 1 FtsK/SpoIIIE family Viral_helicase1 PF01443.13 KLO07624.1 - 0.0012 18.4 0.0 4.4 6.7 0.0 4.5 5 0 0 5 5 5 0 Viral (Superfamily 1) RNA helicase SRP54 PF00448.17 KLO07624.1 - 0.0022 17.4 0.6 4.4 6.6 0.0 3.7 5 0 0 5 5 3 0 SRP54-type protein, GTPase domain ATP_bind_1 PF03029.12 KLO07624.1 - 0.0025 17.3 0.6 7.2 6.0 0.0 3.9 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein KaiC PF06745.8 KLO07624.1 - 0.0028 16.7 0.1 5.6 6.0 0.0 3.7 4 0 0 4 4 4 0 KaiC AAA_21 PF13304.1 KLO07624.1 - 0.011 15.6 2.0 48 3.7 0.0 4.8 5 0 0 5 5 4 0 AAA domain KTI12 PF08433.5 KLO07624.1 - 0.014 14.6 0.0 4 6.5 0.0 4.1 4 0 0 4 4 4 0 Chromatin associated protein KTI12 ArgK PF03308.11 KLO07624.1 - 0.063 12.0 1.2 28 3.3 0.0 4.0 5 0 0 5 5 3 0 ArgK protein PduV-EutP PF10662.4 KLO07624.1 - 0.073 12.5 0.3 3.8 6.9 0.0 3.6 4 0 0 4 4 3 0 Ethanolamine utilisation - propanediol utilisation PhoH PF02562.11 KLO07624.1 - 0.17 11.1 0.2 50 3.0 0.0 3.7 4 0 0 4 4 4 0 PhoH-like protein APS_kinase PF01583.15 KLO07624.1 - 0.27 10.8 0.9 26 4.4 0.0 4.1 4 0 0 4 4 4 0 Adenylylsulphate kinase F-box-like PF12937.2 KLO07625.1 - 0.00094 18.8 0.1 0.0042 16.7 0.1 2.2 1 1 0 1 1 1 1 F-box-like HET PF06985.6 KLO07626.1 - 2.8e-06 27.5 0.1 0.0011 19.1 0.0 2.4 1 1 0 2 2 2 2 Heterokaryon incompatibility protein (HET) Acyl_transf_1 PF00698.16 KLO07628.1 - 3.8e-65 220.3 0.0 1.7e-61 208.3 0.0 3.8 4 0 0 4 4 4 2 Acyl transferase domain DUF1729 PF08354.5 KLO07628.1 - 3.2e-29 100.4 0.3 3.2e-29 100.4 0.2 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF1729) MaoC_dehydratas PF01575.14 KLO07628.1 - 1.3e-28 98.7 0.4 1.3e-27 95.6 0.0 2.9 3 0 0 3 3 3 1 MaoC like domain adh_short_C2 PF13561.1 KLO07628.1 - 9e-22 78.0 0.0 3e-21 76.2 0.0 2.0 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase ketoacyl-synt PF00109.21 KLO07628.1 - 1.6e-21 76.9 1.0 3.3e-21 75.9 0.3 1.9 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain MaoC_dehydrat_N PF13452.1 KLO07628.1 - 6.5e-15 55.0 0.0 2.9e-13 49.7 0.0 2.9 2 0 0 2 2 2 1 N-terminal half of MaoC dehydratase ACPS PF01648.15 KLO07628.1 - 9.3e-15 54.4 0.0 2.9e-14 52.8 0.0 2.0 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily Ketoacyl-synt_C PF02801.17 KLO07628.1 - 1.7e-12 47.1 0.1 1.7e-12 47.1 0.1 2.0 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain NPV_P10 PF05531.7 KLO07629.1 - 1.1 9.5 3.8 3.4 7.9 0.4 3.4 4 1 1 5 5 5 0 Nucleopolyhedrovirus P10 protein DEAD PF00270.24 KLO07630.1 - 4e-35 120.7 0.5 1.1e-34 119.3 0.1 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KLO07630.1 - 1.5e-09 37.5 0.0 8.4e-09 35.1 0.0 2.2 1 1 1 2 2 2 1 Helicase conserved C-terminal domain AAA_22 PF13401.1 KLO07630.1 - 6.1e-05 23.1 0.0 0.0092 16.1 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.1 KLO07630.1 - 0.02 14.4 0.1 0.27 10.7 0.0 2.2 2 0 0 2 2 2 0 AAA domain Bac_DnaA PF00308.13 KLO07630.1 - 0.04 13.5 0.2 0.1 12.2 0.1 1.6 1 1 0 1 1 1 0 Bacterial dnaA protein Sir1 PF11603.3 KLO07630.1 - 0.09 12.9 0.1 1.3 9.1 0.0 2.3 2 0 0 2 2 2 0 Regulatory protein Sir1 Phage_G PF02306.10 KLO07631.1 - 0.14 11.8 0.1 3 7.4 0.0 2.1 2 0 0 2 2 2 0 Major spike protein (G protein) Mitofilin PF09731.4 KLO07632.1 - 3.1e-106 356.3 16.7 3.8e-106 356.0 11.6 1.1 1 0 0 1 1 1 1 Mitochondrial inner membrane protein DUF883 PF05957.8 KLO07632.1 - 0.0031 17.8 2.0 0.0031 17.8 1.4 3.9 3 1 1 4 4 4 1 Bacterial protein of unknown function (DUF883) ox_reductase_C PF08635.5 KLO07633.1 - 1.5e-72 241.6 0.0 2.7e-72 240.8 0.0 1.4 1 0 0 1 1 1 1 Putative oxidoreductase C terminal GFO_IDH_MocA PF01408.17 KLO07633.1 - 4.2e-19 69.2 0.0 6.5e-19 68.6 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 KLO07633.1 - 0.094 12.5 0.0 0.22 11.3 0.0 1.5 1 0 0 1 1 1 0 Oxidoreductase family, C-terminal alpha/beta domain p450 PF00067.17 KLO07634.1 - 2.3e-72 244.0 0.0 3.5e-72 243.3 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 KLO07635.1 - 5.7e-70 236.1 0.0 7.4e-70 235.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 KLO07636.1 - 6.2e-63 212.9 0.0 8.6e-63 212.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 DUF2158 PF09926.4 KLO07636.1 - 0.088 12.2 0.0 0.37 10.2 0.0 2.0 2 0 0 2 2 2 0 Uncharacterized small protein (DUF2158) p450 PF00067.17 KLO07637.1 - 3.5e-68 230.2 0.0 5e-68 229.7 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 NHase_alpha PF02979.11 KLO07638.1 - 0.043 13.0 0.5 2.1 7.6 0.0 2.1 2 0 0 2 2 2 0 Nitrile hydratase, alpha chain DUF3848 PF12959.2 KLO07638.1 - 0.08 12.9 0.1 0.27 11.2 0.1 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF3848) ATP-synt_ab PF00006.20 KLO07639.1 - 8.1e-62 208.5 0.0 1.1e-61 208.1 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 KLO07639.1 - 6.9e-16 58.7 0.0 1.6e-15 57.5 0.0 1.6 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 KLO07639.1 - 1.2e-11 44.6 0.7 2.6e-11 43.5 0.5 1.6 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain HAS-barrel PF09378.5 KLO07639.1 - 0.00045 20.0 0.4 0.001 18.9 0.2 1.5 1 0 0 1 1 1 1 HAS barrel domain Ctf8 PF09696.5 KLO07640.1 - 1.1e-18 67.1 1.1 1.5e-16 60.3 0.1 2.1 1 1 1 2 2 2 2 Ctf8 PH_10 PF15411.1 KLO07642.1 - 1.7e-25 89.4 0.0 3.3e-25 88.5 0.0 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain zf-RING_2 PF13639.1 KLO07642.1 - 2.9e-06 27.0 4.1 1.2e-05 25.0 3.1 1.8 1 1 1 2 2 2 1 Ring finger domain VWA_3 PF13768.1 KLO07642.1 - 4.2e-05 23.2 0.2 0.00074 19.2 0.0 3.0 2 1 0 2 2 2 1 von Willebrand factor type A domain zf-C3HC4_2 PF13923.1 KLO07642.1 - 0.00037 20.4 2.0 0.00085 19.3 1.4 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 KLO07642.1 - 0.0045 17.0 0.1 0.03 14.4 0.0 2.1 2 0 0 2 2 2 1 RING-H2 zinc finger zf-RING_5 PF14634.1 KLO07642.1 - 0.0076 15.9 1.4 0.05 13.3 1.4 2.0 1 1 1 2 2 2 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 KLO07642.1 - 0.011 15.4 3.4 0.011 15.3 0.5 2.0 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KLO07642.1 - 0.023 14.3 0.7 0.044 13.4 0.5 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) FdhE PF04216.7 KLO07642.1 - 0.058 13.1 2.6 0.13 11.9 0.1 2.1 2 0 0 2 2 2 0 Protein involved in formate dehydrogenase formation Zds_C PF08632.5 KLO07643.1 - 2.9e-21 74.5 2.0 3.3e-21 74.4 0.5 1.7 2 0 0 2 2 2 1 Activator of mitotic machinery Cdc14 phosphatase activation C-term DUF2514 PF10721.4 KLO07643.1 - 0.12 12.0 8.2 0.29 10.8 5.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2514) IBR PF01485.16 KLO07646.1 - 3.9e-12 45.8 25.5 1.7e-08 34.1 3.1 3.1 3 1 0 3 3 3 2 IBR domain zf-RING_2 PF13639.1 KLO07646.1 - 4e-05 23.3 0.6 4e-05 23.3 0.4 4.5 2 2 1 3 3 3 1 Ring finger domain zf-C3HC4_2 PF13923.1 KLO07646.1 - 0.013 15.5 0.8 0.013 15.5 0.5 4.2 4 2 1 5 5 5 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KLO07646.1 - 0.014 15.0 0.4 0.014 15.0 0.3 4.0 3 2 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) MTHFR PF02219.12 KLO07647.1 - 7.2e-104 346.8 0.0 9.8e-104 346.4 0.0 1.1 1 0 0 1 1 1 1 Methylenetetrahydrofolate reductase ELMO_CED12 PF04727.8 KLO07648.1 - 1.4e-30 106.0 0.0 2.5e-30 105.2 0.0 1.4 1 0 0 1 1 1 1 ELMO/CED-12 family DUF3361 PF11841.3 KLO07648.1 - 4.1e-12 46.0 0.0 3.8e-10 39.7 0.0 2.5 2 0 0 2 2 2 2 Domain of unknown function (DUF3361) V-ATPase_H_C PF11698.3 KLO07648.1 - 0.093 12.6 0.1 2.3 8.1 0.0 2.5 2 0 0 2 2 2 0 V-ATPase subunit H E1-E2_ATPase PF00122.15 KLO07649.1 - 3.3e-50 170.2 0.9 3.3e-50 170.2 0.6 2.1 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.21 KLO07649.1 - 1.8e-36 126.5 1.3 6.3e-36 124.8 0.2 2.1 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HMA PF00403.21 KLO07649.1 - 6.3e-24 83.9 0.0 2e-10 40.6 0.0 2.7 2 0 0 2 2 2 2 Heavy-metal-associated domain HAD PF12710.2 KLO07649.1 - 3.7e-11 43.5 0.0 1.2e-10 41.9 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 KLO07649.1 - 4.2e-05 23.2 3.1 0.014 14.9 0.7 2.3 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase tRNA-synt_1d PF00750.14 KLO07650.1 - 3e-82 276.2 4.6 1.4e-46 158.9 0.0 2.1 2 0 0 2 2 2 2 tRNA synthetases class I (R) DALR_1 PF05746.10 KLO07650.1 - 4.2e-23 81.5 1.2 8.8e-23 80.5 0.2 2.1 2 0 0 2 2 2 1 DALR anticodon binding domain RNA_pol_Rpb4 PF03874.11 KLO07651.1 - 2.2e-20 72.7 0.1 2.8e-20 72.4 0.1 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb4 DUF4496 PF14908.1 KLO07651.1 - 0.013 15.4 0.1 0.034 14.0 0.0 1.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4496) Pkinase PF00069.20 KLO07652.1 - 4.4e-43 147.3 0.0 6.4e-43 146.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KLO07652.1 - 1.2e-36 126.1 0.0 2.1e-36 125.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KLO07652.1 - 0.00016 20.7 0.0 0.00026 20.0 0.0 1.2 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.17 KLO07652.1 - 0.019 14.3 0.0 0.053 12.8 0.0 1.7 1 0 0 1 1 1 0 RIO1 family p450 PF00067.17 KLO07653.1 - 1.9e-53 181.6 0.0 2.3e-53 181.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 NmrA PF05368.8 KLO07655.1 - 1.2e-27 96.6 0.0 1.6e-27 96.2 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 KLO07655.1 - 5.8e-14 52.5 0.0 9.7e-14 51.7 0.0 1.4 1 0 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 KLO07655.1 - 0.00017 20.3 0.0 0.00024 19.9 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family TrkA_N PF02254.13 KLO07655.1 - 0.002 18.0 0.1 0.0035 17.3 0.0 1.4 1 0 0 1 1 1 1 TrkA-N domain DapB_N PF01113.15 KLO07655.1 - 0.037 13.9 0.1 0.063 13.1 0.1 1.4 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus F420_oxidored PF03807.12 KLO07655.1 - 0.042 14.2 0.4 0.14 12.6 0.3 1.9 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent GFO_IDH_MocA PF01408.17 KLO07655.1 - 0.044 14.3 0.1 0.069 13.6 0.0 1.3 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold Shikimate_DH PF01488.15 KLO07655.1 - 0.057 13.5 0.0 0.096 12.7 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase adh_short PF00106.20 KLO07655.1 - 0.087 12.7 0.1 0.16 11.8 0.1 1.4 1 0 0 1 1 1 0 short chain dehydrogenase NmrA PF05368.8 KLO07656.1 - 1e-26 93.6 0.0 1.4e-26 93.2 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 KLO07656.1 - 9.5e-10 38.7 0.0 2.6e-09 37.3 0.0 1.8 1 1 0 1 1 1 1 NADH(P)-binding TrkA_N PF02254.13 KLO07656.1 - 0.00029 20.8 0.0 0.00057 19.8 0.0 1.5 1 0 0 1 1 1 1 TrkA-N domain Saccharop_dh PF03435.13 KLO07656.1 - 0.00079 18.5 0.0 0.0013 17.7 0.0 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase Shikimate_DH PF01488.15 KLO07656.1 - 0.001 19.1 0.1 0.0025 17.9 0.0 1.6 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase 3Beta_HSD PF01073.14 KLO07656.1 - 0.0026 16.5 0.0 0.0038 15.9 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NmrA PF05368.8 KLO07657.1 - 4.3e-24 85.0 0.0 6e-24 84.5 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 KLO07657.1 - 7.2e-09 35.9 0.2 4.1e-08 33.4 0.1 1.9 1 1 0 1 1 1 1 NADH(P)-binding TrkA_N PF02254.13 KLO07657.1 - 0.0028 17.6 0.1 0.0043 17.0 0.1 1.3 1 0 0 1 1 1 1 TrkA-N domain 3Beta_HSD PF01073.14 KLO07657.1 - 0.0043 15.7 0.1 0.006 15.3 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family CPSase_L_chain PF00289.17 KLO07657.1 - 0.12 12.5 0.0 0.19 11.8 0.0 1.3 1 0 0 1 1 1 0 Carbamoyl-phosphate synthase L chain, N-terminal domain RicinB_lectin_2 PF14200.1 KLO07660.1 - 6.9e-06 26.3 1.9 0.00014 22.1 0.6 2.0 1 1 1 2 2 2 2 Ricin-type beta-trefoil lectin domain-like Pkinase PF00069.20 KLO07661.1 - 1.8e-43 148.5 0.0 2.5e-43 148.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KLO07661.1 - 5.3e-39 133.8 0.0 7.5e-39 133.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KLO07661.1 - 3.6e-05 22.8 0.0 6.2e-05 22.0 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Dynamin_N PF00350.18 KLO07662.1 - 1.1e-27 96.8 0.0 6e-27 94.5 0.0 2.2 1 1 0 1 1 1 1 Dynamin family Dynamin_M PF01031.15 KLO07662.1 - 5.6e-21 74.6 0.0 4.7e-15 55.1 0.0 2.3 1 1 0 2 2 2 2 Dynamin central region GED PF02212.13 KLO07662.1 - 5e-09 35.9 0.1 1.2e-08 34.6 0.1 1.7 1 0 0 1 1 1 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.18 KLO07662.1 - 3.1e-05 23.9 0.0 0.00033 20.5 0.0 2.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 KLO07662.1 - 0.0031 17.9 0.0 0.0096 16.4 0.0 1.9 1 0 0 1 1 1 1 Miro-like protein AAA_29 PF13555.1 KLO07662.1 - 0.018 14.5 0.0 0.082 12.4 0.0 2.0 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_16 PF13191.1 KLO07662.1 - 0.046 13.6 0.0 0.21 11.5 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain FeoB_N PF02421.13 KLO07662.1 - 0.058 12.6 0.2 1.7 7.9 0.0 2.3 2 0 0 2 2 2 0 Ferrous iron transport protein B DUF2830 PF11125.3 KLO07662.1 - 0.14 11.8 0.0 0.35 10.6 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2830) PAH PF02671.16 KLO07663.1 - 1.5e-07 30.8 0.0 2.6e-07 30.1 0.0 1.3 1 0 0 1 1 1 1 Paired amphipathic helix repeat Zn_clus PF00172.13 KLO07664.1 - 0.54 10.2 7.8 0.86 9.5 5.4 1.4 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Zn_clus PF00172.13 KLO07666.1 - 0.057 13.3 7.6 0.1 12.4 5.3 1.4 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF4057 PF13266.1 KLO07667.1 - 0.22 10.9 1.3 0.24 10.8 0.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4057) Zn_clus PF00172.13 KLO07668.1 - 0.43 10.5 9.3 0.73 9.7 6.4 1.4 1 1 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain EGF_CA PF07645.10 KLO07668.1 - 0.87 9.6 3.9 1.4 8.9 2.7 1.3 1 0 0 1 1 1 0 Calcium-binding EGF domain PAH PF02671.16 KLO07671.1 - 3.5e-36 122.5 2.7 2.7e-15 55.7 0.0 3.5 3 0 0 3 3 3 3 Paired amphipathic helix repeat Sin3_corepress PF08295.7 KLO07671.1 - 1.5e-33 114.5 0.3 3.6e-33 113.3 0.2 1.7 1 0 0 1 1 1 1 Sin3 family co-repressor PAH PF02671.16 KLO07672.1 - 9.5e-09 34.7 0.0 1.4e-08 34.1 0.0 1.3 1 0 0 1 1 1 1 Paired amphipathic helix repeat PAH PF02671.16 KLO07673.1 - 2.5e-10 39.7 0.1 5.7e-10 38.6 0.0 1.6 1 1 1 2 2 2 1 Paired amphipathic helix repeat F-box-like PF12937.2 KLO07674.1 - 2.4e-07 30.3 0.5 5.3e-07 29.2 0.3 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KLO07674.1 - 0.12 12.0 4.2 3.4 7.4 0.1 3.0 2 0 0 2 2 2 0 F-box domain Zn_clus PF00172.13 KLO07675.1 - 0.83 9.6 8.0 1.3 9.0 5.5 1.4 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain EGF_CA PF07645.10 KLO07675.1 - 1.3 9.0 4.4 2.2 8.3 3.1 1.3 1 0 0 1 1 1 0 Calcium-binding EGF domain p450 PF00067.17 KLO07676.1 - 1.3e-30 106.3 0.0 1.5e-30 106.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 LRR_6 PF13516.1 KLO07677.1 - 0.046 13.7 0.0 1.2 9.4 0.0 3.1 3 0 0 3 3 3 0 Leucine Rich repeat zf-MYND PF01753.13 KLO07678.1 - 3.3e-11 42.8 14.8 5.6e-11 42.1 10.3 1.4 1 0 0 1 1 1 1 MYND finger zf-Mss51 PF13824.1 KLO07678.1 - 0.00029 20.6 10.6 0.00056 19.7 7.4 1.4 1 0 0 1 1 1 1 Zinc-finger of mitochondrial splicing suppressor 51 zf-HIT PF04438.11 KLO07678.1 - 0.92 9.2 8.3 1.6 8.4 5.8 1.4 1 0 0 1 1 1 0 HIT zinc finger Zn_ribbon_recom PF13408.1 KLO07678.1 - 5.6 7.3 7.4 4.1 7.7 3.3 2.1 2 0 0 2 2 2 0 Recombinase zinc beta ribbon domain zf-Mss51 PF13824.1 KLO07681.1 - 0.0089 15.8 0.6 0.026 14.3 0.4 1.9 1 0 0 1 1 1 1 Zinc-finger of mitochondrial splicing suppressor 51 zf-C2H2 PF00096.21 KLO07681.1 - 0.0089 16.3 2.3 0.032 14.5 0.9 2.6 2 0 0 2 2 2 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KLO07681.1 - 6.8 7.2 10.9 0.14 12.5 0.4 3.3 3 0 0 3 3 3 0 C2H2-type zinc finger zf-MYND PF01753.13 KLO07682.1 - 2.9e-08 33.4 12.8 2.9e-08 33.4 8.8 2.0 2 0 0 2 2 2 1 MYND finger zf-MYND PF01753.13 KLO07683.1 - 1.1e-08 34.7 12.7 2.4e-08 33.7 8.8 1.5 1 0 0 1 1 1 1 MYND finger zf-Mss51 PF13824.1 KLO07683.1 - 0.24 11.2 3.9 0.57 10.0 2.7 1.6 1 0 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 zf-MYND PF01753.13 KLO07684.1 - 2e-10 40.3 8.7 2e-10 40.3 6.0 2.1 2 0 0 2 2 2 1 MYND finger zf-Mss51 PF13824.1 KLO07684.1 - 0.00093 19.0 1.4 0.0023 17.7 1.0 1.7 1 0 0 1 1 1 1 Zinc-finger of mitochondrial splicing suppressor 51 Ecl1 PF12855.2 KLO07684.1 - 0.014 14.6 1.6 0.039 13.2 1.1 1.8 1 0 0 1 1 1 0 Life-span regulatory factor p450 PF00067.17 KLO07685.1 - 1.7e-63 214.7 0.0 3.2e-63 213.8 0.0 1.4 1 1 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 KLO07686.1 - 2.6e-58 197.6 0.0 4.6e-58 196.8 0.0 1.3 1 1 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 KLO07687.1 - 3.9e-64 216.8 0.0 4.9e-64 216.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 KLO07688.1 - 0.053 12.0 0.0 0.25 9.8 0.0 1.8 2 0 0 2 2 2 0 Cytochrome P450 p450 PF00067.17 KLO07689.1 - 1.1e-52 179.0 0.0 1.4e-52 178.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 zf-CCHC PF00098.18 KLO07690.1 - 0.00018 21.3 3.1 0.00027 20.7 2.1 1.3 1 0 0 1 1 1 1 Zinc knuckle Retrotrans_gag PF03732.12 KLO07690.1 - 0.0049 16.9 1.3 0.057 13.4 0.1 2.6 2 0 0 2 2 2 1 Retrotransposon gag protein zf-CCHC_3 PF13917.1 KLO07690.1 - 0.068 12.9 0.8 0.12 12.0 0.6 1.4 1 0 0 1 1 1 0 Zinc knuckle RVP_2 PF08284.6 KLO07691.1 - 0.01 15.8 0.0 0.013 15.4 0.0 1.1 1 0 0 1 1 1 1 Retroviral aspartyl protease p450 PF00067.17 KLO07695.1 - 7.5e-68 229.1 0.0 9.4e-68 228.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Hyccin PF09790.4 KLO07695.1 - 0.17 10.7 0.0 0.32 9.8 0.0 1.4 1 0 0 1 1 1 0 Hyccin Lipase_3 PF01764.20 KLO07696.1 - 1.1e-15 57.5 0.0 2.3e-15 56.4 0.0 1.5 1 0 0 1 1 1 1 Lipase (class 3) DUF2305 PF10230.4 KLO07696.1 - 0.059 12.7 0.2 7.9 5.8 0.0 2.3 2 0 0 2 2 2 0 Uncharacterised conserved protein (DUF2305) p450 PF00067.17 KLO07697.1 - 4.2e-43 147.5 0.0 1.7e-23 82.8 0.0 2.1 2 0 0 2 2 2 2 Cytochrome P450 Glutaredoxin PF00462.19 KLO07698.1 - 1.1e-18 66.9 0.0 1.5e-18 66.5 0.0 1.2 1 0 0 1 1 1 1 Glutaredoxin Thioredoxin_2 PF13098.1 KLO07698.1 - 0.00097 19.3 0.4 0.0025 18.0 0.2 1.7 1 1 0 1 1 1 1 Thioredoxin-like domain GST_N_3 PF13417.1 KLO07698.1 - 0.0011 19.1 0.0 0.0014 18.7 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Thioredoxin_9 PF14595.1 KLO07698.1 - 0.0012 18.3 0.0 0.0017 17.9 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_3 PF13192.1 KLO07698.1 - 0.0032 17.2 0.0 0.005 16.6 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin domain DUF836 PF05768.9 KLO07698.1 - 0.006 16.8 0.0 0.0082 16.3 0.0 1.3 1 0 0 1 1 1 1 Glutaredoxin-like domain (DUF836) DSBA PF01323.15 KLO07698.1 - 0.01 15.3 0.2 0.14 11.6 0.1 2.0 1 1 0 2 2 2 0 DSBA-like thioredoxin domain Zn_ribbon_2 PF12674.2 KLO07698.1 - 0.013 15.8 0.1 0.017 15.4 0.1 1.3 1 0 0 1 1 1 0 Putative zinc ribbon domain DUF3228 PF11539.3 KLO07698.1 - 0.015 14.3 0.1 0.016 14.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3228) DUF953 PF06110.6 KLO07698.1 - 0.02 14.3 0.1 0.13 11.6 0.0 1.9 1 1 1 2 2 2 0 Eukaryotic protein of unknown function (DUF953) Thioredoxin_7 PF13899.1 KLO07698.1 - 0.034 14.1 0.0 0.057 13.4 0.0 1.4 1 0 0 1 1 1 0 Thioredoxin-like Thioredoxin_4 PF13462.1 KLO07698.1 - 0.15 12.0 0.5 9.2 6.2 0.0 2.1 1 1 1 2 2 2 0 Thioredoxin F-box-like PF12937.2 KLO07699.1 - 5.4e-05 22.8 0.2 0.0004 20.0 0.1 2.2 1 1 0 1 1 1 1 F-box-like LRR_4 PF12799.2 KLO07700.1 - 0.37 10.4 5.0 2.8 7.6 0.1 4.1 4 0 0 4 4 4 0 Leucine Rich repeats (2 copies) F-box-like PF12937.2 KLO07701.1 - 8.8e-05 22.1 0.2 0.00082 19.0 0.2 2.5 1 1 0 1 1 1 1 F-box-like LRR_4 PF12799.2 KLO07701.1 - 1.2 8.8 5.7 1.2 8.8 0.1 3.6 4 0 0 4 4 4 0 Leucine Rich repeats (2 copies) F-box-like PF12937.2 KLO07702.1 - 5.1e-06 26.0 1.4 0.026 14.2 0.2 2.8 3 0 0 3 3 3 2 F-box-like F-box-like PF12937.2 KLO07703.1 - 0.0041 16.8 0.1 0.014 15.1 0.1 1.9 1 0 0 1 1 1 1 F-box-like LRR_2 PF07723.8 KLO07703.1 - 0.039 14.4 1.5 1.7 9.3 0.0 4.3 4 0 0 4 4 4 0 Leucine Rich Repeat F-box-like PF12937.2 KLO07704.1 - 1.5e-07 31.0 0.1 4.8e-07 29.4 0.1 2.0 1 1 0 1 1 1 1 F-box-like F-box-like PF12937.2 KLO07705.1 - 0.00018 21.1 5.0 0.00028 20.5 1.2 2.9 2 2 0 2 2 2 1 F-box-like LRR_8 PF13855.1 KLO07705.1 - 0.073 12.8 0.1 29 4.4 0.0 3.6 4 0 0 4 4 4 0 Leucine rich repeat Ribonuc_L-PSP PF01042.16 KLO07706.1 - 2e-29 101.7 0.0 2.2e-29 101.6 0.0 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP zf-C3HC4_2 PF13923.1 KLO07707.1 - 1.6e-10 40.8 11.4 2.8e-10 40.0 7.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KLO07707.1 - 5.5e-10 38.7 11.2 1e-09 37.8 7.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KLO07707.1 - 3.1e-08 33.3 9.0 5.6e-08 32.4 6.2 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 KLO07707.1 - 1.1e-07 31.3 7.0 1.9e-07 30.6 4.9 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KLO07707.1 - 1.1e-05 25.0 9.6 2e-05 24.2 6.7 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 KLO07707.1 - 2.7e-05 23.9 10.6 5.6e-05 22.9 7.4 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 KLO07707.1 - 0.00058 19.5 7.5 0.0024 17.5 5.2 2.1 1 1 0 1 1 1 1 RING-type zinc-finger zf-rbx1 PF12678.2 KLO07707.1 - 0.0057 16.7 2.9 0.013 15.6 2.0 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger zf-MIZ PF02891.15 KLO07707.1 - 0.024 14.1 8.9 0.047 13.2 6.1 1.5 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger zf-Nse PF11789.3 KLO07707.1 - 0.026 14.0 5.4 0.055 12.9 3.8 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit Ribosomal_S19 PF00203.16 KLO07707.1 - 0.092 12.3 0.1 0.18 11.4 0.1 1.4 1 0 0 1 1 1 0 Ribosomal protein S19 zf-Apc11 PF12861.2 KLO07707.1 - 0.14 11.9 3.1 0.26 11.1 2.1 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Tmemb_cc2 PF10267.4 KLO07707.1 - 0.3 9.6 2.0 0.46 9.0 1.4 1.2 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein zf-RING_6 PF14835.1 KLO07707.1 - 0.97 9.2 6.4 2.5 7.9 4.4 1.7 1 1 0 1 1 1 0 zf-RING of BARD1-type protein DUF1840 PF08895.6 KLO07707.1 - 2.3 8.2 4.4 1.8 8.6 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1840) DUF1793 PF08760.6 KLO07710.1 - 4.5e-27 94.9 0.2 9.9e-27 93.8 0.1 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF1793) Bac_rhamnosid PF05592.6 KLO07710.1 - 0.04 12.1 0.0 0.09 10.9 0.0 1.5 1 1 0 1 1 1 0 Bacterial alpha-L-rhamnosidase DUF1793 PF08760.6 KLO07711.1 - 5.8e-38 130.4 0.0 1e-37 129.5 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1793) Bac_rhamnosid PF05592.6 KLO07711.1 - 0.02 13.0 0.0 0.037 12.2 0.0 1.4 1 0 0 1 1 1 0 Bacterial alpha-L-rhamnosidase DUF1793 PF08760.6 KLO07712.1 - 7.7e-34 117.0 0.0 2.1e-33 115.6 0.0 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF1793) GBA2_N PF12215.3 KLO07712.1 - 0.0062 15.7 0.2 0.011 14.8 0.1 1.3 1 0 0 1 1 1 1 beta-Glucocerebrosidase 2 N terminal DUF1793 PF08760.6 KLO07713.1 - 1.1e-34 119.7 0.0 2.2e-34 118.7 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1793) F-box-like PF12937.2 KLO07716.1 - 5.1e-07 29.3 0.1 5.1e-07 29.3 0.1 2.5 3 1 0 3 3 3 1 F-box-like F-box PF00646.28 KLO07716.1 - 0.014 15.0 0.4 7.3 6.3 0.0 3.2 3 0 0 3 3 3 0 F-box domain F-box-like PF12937.2 KLO07719.1 - 5.5e-09 35.6 0.3 1.6e-08 34.1 0.2 1.9 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KLO07719.1 - 0.00051 19.6 0.4 0.95 9.1 0.1 3.0 2 0 0 2 2 2 2 F-box domain LRR_8 PF13855.1 KLO07719.1 - 0.00079 19.1 0.8 15 5.4 0.0 4.7 4 1 0 4 4 4 2 Leucine rich repeat Transpos_assoc PF13963.1 KLO07720.1 - 0.2 11.6 1.5 1.4 8.9 0.2 2.3 2 0 0 2 2 2 0 Transposase-associated domain BTB PF00651.26 KLO07721.1 - 1.7e-06 28.0 0.0 5.3e-06 26.3 0.0 1.8 2 1 0 2 2 2 1 BTB/POZ domain DUF3875 PF12991.2 KLO07721.1 - 0.1 12.2 0.0 2.4 7.9 0.0 2.9 3 0 0 3 3 3 0 Domain of unknown function, B. Theta Gene description (DUF3875) BTB PF00651.26 KLO07722.1 - 6.2e-05 22.9 0.1 0.00026 20.9 0.0 2.0 2 1 0 2 2 2 1 BTB/POZ domain BTB PF00651.26 KLO07723.1 - 0.00011 22.1 0.0 0.0004 20.3 0.0 1.9 2 1 0 2 2 2 1 BTB/POZ domain BTB PF00651.26 KLO07724.1 - 5.7e-06 26.2 0.0 0.00041 20.3 0.0 2.4 2 0 0 2 2 2 2 BTB/POZ domain BTB PF00651.26 KLO07725.1 - 0.00064 19.6 0.1 0.017 15.1 0.0 2.8 2 1 0 2 2 2 1 BTB/POZ domain DUF919 PF06034.6 KLO07725.1 - 0.025 14.1 0.2 0.049 13.2 0.1 1.4 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF919) BTB PF00651.26 KLO07726.1 - 0.0022 17.9 0.1 0.013 15.4 0.0 2.3 2 1 0 2 2 2 1 BTB/POZ domain BTB PF00651.26 KLO07727.1 - 0.0044 16.9 0.0 0.018 15.0 0.0 2.0 3 0 0 3 3 3 1 BTB/POZ domain Big_3 PF07523.7 KLO07727.1 - 0.13 12.3 0.0 0.24 11.5 0.0 1.4 1 0 0 1 1 1 0 Bacterial Ig-like domain (group 3) BTB PF00651.26 KLO07728.1 - 0.00082 19.3 0.0 0.002 18.1 0.0 1.8 1 1 0 1 1 1 1 BTB/POZ domain BTB PF00651.26 KLO07729.1 - 0.0061 16.5 0.0 0.051 13.5 0.0 2.1 2 0 0 2 2 2 1 BTB/POZ domain BTB PF00651.26 KLO07730.1 - 0.0062 16.5 0.0 0.024 14.6 0.0 2.0 1 1 0 1 1 1 1 BTB/POZ domain BTB PF00651.26 KLO07731.1 - 0.00024 21.0 0.0 0.00089 19.2 0.0 2.0 2 1 0 2 2 2 1 BTB/POZ domain BTB PF00651.26 KLO07732.1 - 0.00025 21.0 0.0 0.00096 19.1 0.0 2.1 1 1 0 1 1 1 1 BTB/POZ domain BTB PF00651.26 KLO07733.1 - 0.0017 18.3 0.1 0.016 15.1 0.0 2.3 2 1 1 3 3 3 1 BTB/POZ domain BTB PF00651.26 KLO07734.1 - 0.00026 20.9 0.2 0.0069 16.3 0.0 2.5 2 1 0 2 2 2 1 BTB/POZ domain BTB PF00651.26 KLO07735.1 - 0.0013 18.6 0.0 0.0033 17.3 0.0 1.7 1 1 0 1 1 1 1 BTB/POZ domain BTB PF00651.26 KLO07736.1 - 0.0033 17.3 0.1 0.0043 17.0 0.1 1.4 1 1 0 1 1 1 1 BTB/POZ domain ACC_central PF08326.7 KLO07736.1 - 0.082 11.0 0.1 0.099 10.7 0.0 1.0 1 0 0 1 1 1 0 Acetyl-CoA carboxylase, central region DUF1196 PF06709.6 KLO07736.1 - 0.12 12.2 0.1 0.23 11.3 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1196) Rhabdo_glycop PF00974.13 KLO07737.1 - 0.09 10.9 0.5 0.13 10.4 0.3 1.2 1 0 0 1 1 1 0 Rhabdovirus spike glycoprotein Retrotrans_gag PF03732.12 KLO07738.1 - 2.2e-06 27.6 0.3 4.9e-06 26.5 0.2 1.5 1 0 0 1 1 1 1 Retrotransposon gag protein Lipase_3 PF01764.20 KLO07740.1 - 1.5e-21 76.5 0.0 2.2e-21 75.9 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.2 KLO07740.1 - 0.00024 21.0 0.1 0.00037 20.4 0.1 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KLO07740.1 - 0.014 14.9 0.1 0.064 12.7 0.0 1.9 2 0 0 2 2 2 0 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KLO07740.1 - 0.033 13.9 0.0 0.047 13.4 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase family DUF2974 PF11187.3 KLO07740.1 - 0.12 11.6 0.0 0.91 8.8 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2974) BTB PF00651.26 KLO07741.1 - 4.4e-08 33.0 0.1 1.8e-07 31.1 0.0 2.0 2 0 0 2 2 2 1 BTB/POZ domain BTB PF00651.26 KLO07742.1 - 1.5e-07 31.4 0.0 4.1e-07 29.9 0.0 1.7 1 1 0 1 1 1 1 BTB/POZ domain BTB PF00651.26 KLO07743.1 - 7.7e-07 29.0 0.0 1.9e-06 27.8 0.0 1.6 1 1 0 1 1 1 1 BTB/POZ domain BTB PF00651.26 KLO07744.1 - 5.4e-06 26.3 0.0 1.7e-05 24.7 0.0 1.8 1 1 0 1 1 1 1 BTB/POZ domain BTB PF00651.26 KLO07745.1 - 5.2e-06 26.4 0.0 1.1e-05 25.4 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain BTB PF00651.26 KLO07747.1 - 3.4e-05 23.8 0.2 0.0001 22.2 0.1 1.9 1 1 0 1 1 1 1 BTB/POZ domain BTB PF00651.26 KLO07748.1 - 1.2e-05 25.2 0.1 4.2e-05 23.5 0.0 1.9 2 0 0 2 2 2 1 BTB/POZ domain DUF4419 PF14388.1 KLO07749.1 - 6.7e-63 212.6 0.0 8.1e-63 212.4 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4419) DUF4448 PF14610.1 KLO07750.1 - 1.4e-09 37.6 0.2 2.5e-09 36.8 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) GPI-anchored PF10342.4 KLO07750.1 - 4.8e-05 23.7 2.1 9.5e-05 22.7 1.5 1.5 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family DUF3733 PF12534.3 KLO07751.1 - 0.1 11.9 0.2 0.1 11.9 0.2 2.2 2 0 0 2 2 2 0 Leucine-rich repeat containing protein 8 HAMP PF00672.20 KLO07752.1 - 1.1e-47 160.0 24.2 3.9e-08 33.3 0.3 8.8 8 1 1 9 9 9 7 HAMP domain HATPase_c PF02518.21 KLO07752.1 - 7.6e-28 96.4 0.1 2.3e-27 94.8 0.1 1.9 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 KLO07752.1 - 7.4e-24 83.9 0.6 1.5e-22 79.6 0.1 2.9 2 1 0 2 2 2 1 Response regulator receiver domain HisKA PF00512.20 KLO07752.1 - 1.1e-17 63.7 1.0 5.8e-17 61.4 0.7 2.4 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain REF PF05755.7 KLO07752.1 - 0.0076 16.0 7.2 0.46 10.1 0.0 3.9 3 2 1 5 5 5 2 Rubber elongation factor protein (REF) PurA PF04845.8 KLO07752.1 - 0.022 13.8 0.2 1.8 7.5 0.0 2.8 2 1 0 3 3 3 0 PurA ssDNA and RNA-binding protein Apolipoprotein PF01442.13 KLO07752.1 - 0.042 13.3 0.5 3.8 6.9 0.0 3.3 2 1 0 2 2 2 0 Apolipoprotein A1/A4/E domain PilJ PF13675.1 KLO07752.1 - 0.16 12.3 2.1 70 3.7 0.0 5.0 5 2 1 6 6 6 0 Type IV pili methyl-accepting chemotaxis transducer N-term AcylCoA_dehyd_C PF12186.3 KLO07752.1 - 0.47 10.3 9.9 28 4.6 0.0 6.2 7 1 1 8 8 8 0 Acyl-CoA dehydrogenase C terminal Syntaxin PF00804.20 KLO07752.1 - 2.2 8.5 7.3 23 5.2 0.4 4.8 4 2 2 6 6 6 0 Syntaxin DUF2365 PF10157.4 KLO07752.1 - 5.1 6.9 20.6 3.4 7.5 0.0 6.7 6 3 1 8 8 8 0 Uncharacterized conserved protein (DUF2365) DUF368 PF04018.8 KLO07756.1 - 0.0003 20.0 1.6 0.0003 20.0 1.1 1.5 2 0 0 2 2 2 1 Domain of unknown function (DUF368) DUF2919 PF11143.3 KLO07756.1 - 0.65 9.8 11.6 2.6 7.8 1.5 3.3 2 1 0 3 3 3 0 Protein of unknown function (DUF2919) DUF1212 PF06738.7 KLO07760.1 - 3.7e-38 130.9 8.5 7.1e-36 123.4 0.8 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF1212) DUF3815 PF12821.2 KLO07760.1 - 7e-18 64.8 5.7 7e-18 64.8 4.0 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF3815) RNA_polI_A34 PF08208.6 KLO07760.1 - 1.1 8.9 18.5 1.2 8.8 4.0 2.6 2 0 0 2 2 2 0 DNA-directed RNA polymerase I subunit RPA34.5 Herpes_DNAp_acc PF04929.7 KLO07760.1 - 3.8 6.3 11.9 2.6 6.9 1.4 2.5 2 0 0 2 2 2 0 Herpes DNA replication accessory factor RR_TM4-6 PF06459.7 KLO07760.1 - 4 7.2 10.4 24 4.7 0.1 2.4 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 Med19 PF10278.4 KLO07760.1 - 6.6 6.3 25.4 1.4 8.5 8.1 2.5 2 0 0 2 2 2 0 Mediator of RNA pol II transcription subunit 19 PLDc PF00614.17 KLO07761.1 - 2.8e-17 61.9 3.4 7.1e-10 38.3 0.2 2.8 2 0 0 2 2 2 2 Phospholipase D Active site motif PLDc_2 PF13091.1 KLO07761.1 - 5.3e-15 55.2 0.0 4.1e-07 29.7 0.0 3.6 3 0 0 3 3 3 3 PLD-like domain Rotamase_3 PF13616.1 KLO07763.1 - 0.099 12.9 0.0 0.18 12.0 0.0 1.3 1 0 0 1 1 1 0 PPIC-type PPIASE domain Rotamase PF00639.16 KLO07763.1 - 0.12 13.1 0.0 0.22 12.2 0.0 1.4 1 0 0 1 1 1 0 PPIC-type PPIASE domain WaaY PF06176.6 KLO07766.1 - 0.038 13.2 0.0 0.06 12.5 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide core biosynthesis protein (WaaY) APH PF01636.18 KLO07766.1 - 0.15 11.7 0.1 0.26 10.9 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family NAD_binding_9 PF13454.1 KLO07767.1 - 0.00024 20.9 0.1 0.00037 20.2 0.1 1.2 1 0 0 1 1 1 1 FAD-NAD(P)-binding FSH1 PF03959.8 KLO07769.1 - 5.6e-48 163.1 0.0 8.9e-48 162.5 0.0 1.3 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_5 PF12695.2 KLO07769.1 - 1.2e-10 41.2 0.0 5.2e-10 39.2 0.0 2.1 2 1 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KLO07769.1 - 1.7e-05 24.7 0.2 0.23 11.2 0.0 2.4 1 1 0 2 2 2 2 Alpha/beta hydrolase family DLH PF01738.13 KLO07769.1 - 0.00044 19.6 0.0 0.0011 18.3 0.0 1.5 1 1 0 1 1 1 1 Dienelactone hydrolase family Peptidase_S9 PF00326.16 KLO07769.1 - 0.0074 15.5 0.1 0.31 10.2 0.0 2.2 2 0 0 2 2 2 1 Prolyl oligopeptidase family DUF2048 PF09752.4 KLO07769.1 - 0.0098 14.7 0.1 0.25 10.1 0.1 2.1 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2048) Myc_N PF01056.13 KLO07769.1 - 0.049 12.7 0.0 0.082 12.0 0.0 1.2 1 0 0 1 1 1 0 Myc amino-terminal region Tmemb_14 PF03647.8 KLO07769.1 - 0.067 13.5 0.2 0.12 12.7 0.1 1.4 1 0 0 1 1 1 0 Transmembrane proteins 14C Abhydrolase_2 PF02230.11 KLO07769.1 - 0.093 12.1 1.1 0.35 10.2 0.3 2.2 2 1 0 2 2 2 0 Phospholipase/Carboxylesterase p450 PF00067.17 KLO07770.1 - 1.8e-66 224.5 0.0 2.4e-66 224.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 JAB PF01398.16 KLO07771.1 - 2.3e-27 94.9 0.1 4.9e-27 93.9 0.1 1.5 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Prok-JAB PF14464.1 KLO07771.1 - 1e-07 31.4 0.0 1.7e-07 30.7 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain DUF4404 PF14357.1 KLO07771.1 - 0.013 15.9 2.6 0.023 15.1 1.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4404) IncA PF04156.9 KLO07771.1 - 0.017 14.7 2.6 0.029 13.9 1.8 1.3 1 0 0 1 1 1 0 IncA protein Peptidase_S9 PF00326.16 KLO07772.1 - 3.6e-35 121.1 0.0 6.6e-35 120.2 0.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_6 PF12697.2 KLO07772.1 - 5e-13 49.4 0.1 1.2e-12 48.2 0.1 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KLO07772.1 - 1.4e-12 47.5 0.1 2.8e-12 46.6 0.1 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family DLH PF01738.13 KLO07772.1 - 2.3e-06 27.0 0.0 4.2e-06 26.2 0.0 1.4 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_3 PF07859.8 KLO07772.1 - 9.8e-05 22.0 0.0 0.00017 21.2 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_1 PF00561.15 KLO07772.1 - 0.00021 20.9 1.0 0.12 11.8 0.3 2.4 1 1 1 2 2 2 2 alpha/beta hydrolase fold FSH1 PF03959.8 KLO07772.1 - 0.033 13.6 0.0 0.08 12.3 0.0 1.6 1 0 0 1 1 1 0 Serine hydrolase (FSH1) Abhydrolase_2 PF02230.11 KLO07772.1 - 0.11 11.9 0.1 0.23 10.8 0.0 1.5 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase AXE1 PF05448.7 KLO07772.1 - 0.11 10.9 0.0 0.24 9.8 0.0 1.5 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) Abhydrolase_4 PF08386.5 KLO07772.1 - 0.11 12.3 0.0 0.25 11.2 0.0 1.5 1 0 0 1 1 1 0 TAP-like protein DUF4614 PF15391.1 KLO07773.1 - 1.2 8.8 17.2 3.2 7.4 7.6 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4614) IMS PF00817.15 KLO07775.1 - 1.1e-42 145.3 0.1 2.3e-42 144.3 0.1 1.6 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.3 KLO07775.1 - 2.9e-13 49.8 0.0 1.2e-12 47.9 0.0 2.0 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain DUF4414 PF14377.1 KLO07775.1 - 1e-05 25.4 0.1 0.0033 17.3 0.1 2.7 2 0 0 2 2 2 2 Domain of unknown function (DUF4414) IMS_HHH PF11798.3 KLO07775.1 - 0.00041 20.2 0.0 0.0023 17.8 0.0 2.3 2 0 0 2 2 2 1 IMS family HHH motif DUF1805 PF08827.6 KLO07775.1 - 0.055 13.2 0.0 0.23 11.2 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF1805) Zn_clus PF00172.13 KLO07777.1 - 0.076 12.9 12.6 0.14 12.1 8.7 1.4 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Ribonucleas_3_3 PF14622.1 KLO07780.1 - 1.5e-10 41.1 0.1 4.9e-10 39.4 0.0 1.9 1 1 0 1 1 1 1 Ribonuclease-III-like FSH1 PF03959.8 KLO07781.1 - 2.7e-45 154.4 0.0 3.6e-45 154.0 0.0 1.2 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_5 PF12695.2 KLO07781.1 - 1.4e-06 28.1 0.0 2.6e-06 27.2 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KLO07781.1 - 5.9e-05 23.0 0.0 0.11 12.3 0.0 2.4 1 1 1 2 2 2 2 Alpha/beta hydrolase family DLH PF01738.13 KLO07781.1 - 0.0005 19.4 0.0 0.001 18.3 0.0 1.4 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_2 PF02230.11 KLO07781.1 - 0.13 11.7 0.4 0.73 9.2 0.1 2.2 2 1 0 2 2 2 0 Phospholipase/Carboxylesterase Abhydrolase_1 PF00561.15 KLO07781.1 - 0.15 11.6 0.2 9 5.7 0.1 2.5 3 0 0 3 3 3 0 alpha/beta hydrolase fold TPR_12 PF13424.1 KLO07784.1 - 1.4e-49 165.8 34.5 8.7e-10 38.4 0.2 7.8 4 1 5 9 9 9 8 Tetratricopeptide repeat TPR_10 PF13374.1 KLO07784.1 - 1.5e-36 123.2 35.9 8e-05 22.4 0.1 11.6 11 0 0 11 11 11 9 Tetratricopeptide repeat DUF4404 PF14357.1 KLO07784.1 - 2.9e-18 66.0 4.7 0.22 11.9 0.0 10.3 9 0 0 9 9 9 2 Domain of unknown function (DUF4404) TPR_11 PF13414.1 KLO07784.1 - 8.7e-14 50.9 35.8 0.0035 16.9 0.2 8.0 4 1 5 9 9 9 6 TPR repeat AAA_16 PF13191.1 KLO07784.1 - 1.4e-08 34.9 3.9 1.3e-05 25.2 0.0 4.9 4 2 0 4 4 4 1 AAA ATPase domain TPR_1 PF00515.23 KLO07784.1 - 1.2e-07 31.0 3.8 7.8 6.2 0.0 7.2 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_17 PF13431.1 KLO07784.1 - 7.7e-06 25.7 28.7 1.2 9.5 0.0 10.2 11 0 0 11 11 9 2 Tetratricopeptide repeat DUF3856 PF12968.2 KLO07784.1 - 1.8e-05 24.6 19.1 0.071 12.9 0.5 5.9 4 1 3 7 7 7 2 Domain of Unknown Function (DUF3856) TPR_16 PF13432.1 KLO07784.1 - 9.1e-05 23.0 20.6 13 6.5 0.1 7.7 5 2 2 7 7 7 0 Tetratricopeptide repeat Apc5 PF12862.2 KLO07784.1 - 9.5e-05 22.1 19.6 3.6 7.4 0.1 8.8 4 2 6 10 10 10 1 Anaphase-promoting complex subunit 5 DUF627 PF04781.7 KLO07784.1 - 0.0008 19.0 3.3 9.8 5.8 0.0 6.3 3 2 4 7 7 7 0 Protein of unknown function (DUF627) AAA_22 PF13401.1 KLO07784.1 - 0.0029 17.7 0.1 0.4 10.8 0.0 4.2 4 1 1 5 5 4 1 AAA domain AAA_19 PF13245.1 KLO07784.1 - 0.0049 16.6 0.0 0.016 14.9 0.0 1.9 1 0 0 1 1 1 1 Part of AAA domain Peptidase_M16 PF00675.15 KLO07784.1 - 0.0074 16.0 2.3 2.1 8.0 0.0 4.5 2 1 2 4 4 4 1 Insulinase (Peptidase family M16) NB-ARC PF00931.17 KLO07784.1 - 0.011 14.6 0.0 0.069 11.9 0.0 2.3 2 1 0 2 2 2 0 NB-ARC domain NACHT PF05729.7 KLO07784.1 - 0.012 15.2 0.0 0.032 13.8 0.0 1.7 1 0 0 1 1 1 0 NACHT domain TPR_8 PF13181.1 KLO07784.1 - 0.021 14.6 2.2 15 5.6 0.0 4.6 4 0 0 4 4 4 0 Tetratricopeptide repeat HAD_2 PF13419.1 KLO07784.1 - 0.021 15.0 0.1 13 5.9 0.0 4.8 2 1 1 3 3 3 0 Haloacid dehalogenase-like hydrolase NTPase_1 PF03266.10 KLO07784.1 - 0.041 13.5 0.0 0.24 11.1 0.0 2.3 2 0 0 2 2 2 0 NTPase AAA_25 PF13481.1 KLO07784.1 - 0.048 13.0 0.0 0.2 11.0 0.0 2.2 1 0 0 1 1 1 0 AAA domain AAA PF00004.24 KLO07784.1 - 0.07 13.3 0.0 0.23 11.6 0.0 1.9 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.1 KLO07784.1 - 0.085 13.1 0.0 0.47 10.7 0.0 2.4 2 0 0 2 2 1 0 AAA domain Zeta_toxin PF06414.7 KLO07784.1 - 0.11 11.5 0.0 0.3 10.1 0.0 1.7 1 0 0 1 1 1 0 Zeta toxin DUF2075 PF09848.4 KLO07784.1 - 0.14 11.0 0.0 0.88 8.4 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) TPR_2 PF07719.12 KLO07784.1 - 0.16 11.9 15.6 11 6.1 0.1 8.4 9 0 0 9 9 9 0 Tetratricopeptide repeat AAA_17 PF13207.1 KLO07784.1 - 0.17 12.6 0.1 1.1 10.1 0.0 2.5 2 0 0 2 2 2 0 AAA domain HisKA_2 PF07568.7 KLO07784.1 - 0.75 9.6 4.3 10 6.0 0.0 4.1 4 1 0 4 4 4 0 Histidine kinase TPR_7 PF13176.1 KLO07784.1 - 2 8.4 18.8 44 4.2 0.0 7.6 8 0 0 8 8 7 0 Tetratricopeptide repeat NTR2 PF15458.1 KLO07784.1 - 5.4 6.1 10.9 19 4.4 0.1 5.3 3 2 1 6 6 6 0 Nineteen complex-related protein 2 UPF0020 PF01170.13 KLO07784.1 - 6.2 6.3 7.1 1.2e+02 2.1 0.0 5.1 6 0 0 6 6 6 0 Putative RNA methylase family UPF0020 Sugar_tr PF00083.19 KLO07785.1 - 2.1e-117 392.4 27.0 9.5e-117 390.3 18.7 1.8 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KLO07785.1 - 1.6e-15 56.6 51.8 1.4e-11 43.6 14.8 2.9 1 1 1 3 3 3 2 Major Facilitator Superfamily p450 PF00067.17 KLO07786.1 - 1.6e-71 241.2 0.0 1.9e-71 240.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Cellulase PF00150.13 KLO07787.1 - 4.6e-09 35.8 0.2 6.7e-08 32.0 0.2 2.1 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) F-box-like PF12937.2 KLO07788.1 - 0.0057 16.3 0.2 0.029 14.1 0.0 2.3 2 0 0 2 2 2 1 F-box-like tRNA_edit PF04073.10 KLO07788.1 - 0.1 12.4 0.0 0.2 11.4 0.0 1.4 1 0 0 1 1 1 0 Aminoacyl-tRNA editing domain Cep57_CLD_2 PF14197.1 KLO07788.1 - 0.14 12.0 0.7 0.31 11.0 0.5 1.5 1 0 0 1 1 1 0 Centrosome localisation domain of PPC89 DUF1708 PF08101.6 KLO07791.1 - 9e-17 61.0 0.0 2.8e-15 56.1 0.0 2.1 2 0 0 2 2 2 2 Domain of unknown function (DUF1708) RhoGAP PF00620.22 KLO07791.1 - 0.00021 20.9 0.0 0.00046 19.8 0.0 1.5 1 0 0 1 1 1 1 RhoGAP domain Tetraspannin PF00335.15 KLO07793.1 - 2.6e-09 36.7 13.7 3.7e-09 36.1 9.5 1.2 1 0 0 1 1 1 1 Tetraspanin family VSP PF03302.8 KLO07794.1 - 0.00046 18.9 34.5 0.00046 18.9 23.9 6.1 1 1 5 6 6 6 5 Giardia variant-specific surface protein hEGF PF12661.2 KLO07794.1 - 0.01 15.8 3.5 0.01 15.8 2.4 8.5 9 0 0 9 9 9 2 Human growth factor-like EGF Laminin_EGF PF00053.19 KLO07794.1 - 0.013 15.3 18.5 0.013 15.3 12.8 10.0 1 1 5 6 6 6 0 Laminin EGF-like (Domains III and V) Metallophos PF00149.23 KLO07795.1 - 1.2e-42 145.5 0.4 1.5e-42 145.3 0.3 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Pro_isomerase PF00160.16 KLO07797.1 - 2.2e-46 157.8 0.0 2.5e-46 157.7 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD MAD PF05557.8 KLO07802.1 - 2.9e-37 128.1 43.8 1.9e-36 125.4 17.6 3.5 2 1 0 2 2 2 2 Mitotic checkpoint protein ATG16 PF08614.6 KLO07802.1 - 6e-08 32.7 63.6 0.0012 18.7 1.8 6.3 4 2 1 5 5 5 2 Autophagy protein 16 (ATG16) TACC PF05010.9 KLO07802.1 - 8.5e-08 32.2 1.2 3.2e-05 23.7 0.7 5.3 3 2 2 5 5 5 2 Transforming acidic coiled-coil-containing protein (TACC) Rootletin PF15035.1 KLO07802.1 - 1.8e-05 24.7 1.9 1.8e-05 24.7 1.3 5.1 4 2 1 5 5 5 2 Ciliary rootlet component, centrosome cohesion Reo_sigmaC PF04582.7 KLO07802.1 - 0.00048 19.4 28.3 0.12 11.5 3.7 4.6 3 1 0 4 4 4 3 Reovirus sigma C capsid protein WEMBL PF05701.6 KLO07802.1 - 0.00088 17.8 13.1 0.00088 17.8 9.1 4.2 4 0 0 4 4 4 2 Weak chloroplast movement under blue light DUF4201 PF13870.1 KLO07802.1 - 0.0021 17.5 51.5 0.021 14.2 1.0 6.9 6 1 1 7 7 7 4 Domain of unknown function (DUF4201) Cep57_CLD_2 PF14197.1 KLO07802.1 - 0.0099 15.8 2.4 0.0099 15.8 1.7 9.1 9 1 0 9 9 8 1 Centrosome localisation domain of PPC89 CENP-F_leu_zip PF10473.4 KLO07802.1 - 0.041 13.7 64.6 0.025 14.4 2.6 7.2 6 1 0 7 7 7 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Fib_alpha PF08702.5 KLO07802.1 - 0.056 13.5 26.8 0.61 10.2 0.2 6.0 5 1 1 6 6 6 0 Fibrinogen alpha/beta chain family Atg14 PF10186.4 KLO07802.1 - 0.48 9.3 59.3 0.16 10.8 2.9 6.1 4 2 1 6 6 6 0 UV radiation resistance protein and autophagy-related subunit 14 DUF869 PF05911.6 KLO07802.1 - 1.4 7.0 40.4 2.7 6.1 0.1 4.4 3 1 0 3 3 3 0 Plant protein of unknown function (DUF869) IncA PF04156.9 KLO07802.1 - 1.5 8.3 79.1 0.22 11.0 7.9 6.9 2 2 4 6 6 6 0 IncA protein DUF3138 PF11336.3 KLO07802.1 - 3.7 5.6 8.9 8.6 4.4 0.0 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF3138) HAP1_N PF04849.8 KLO07802.1 - 3.8 6.3 47.6 0.37 9.7 3.8 5.0 3 2 1 5 5 5 0 HAP1 N-terminal conserved region Phage_GP20 PF06810.6 KLO07802.1 - 5.5 6.4 40.2 0.21 10.9 1.3 6.4 5 2 1 6 6 6 0 Phage minor structural protein GP20 NPV_P10 PF05531.7 KLO07802.1 - 8.3 6.7 23.4 1 9.6 0.3 5.7 5 0 0 5 5 5 0 Nucleopolyhedrovirus P10 protein NIF PF03031.13 KLO07803.1 - 5.4e-10 39.1 0.0 2.9e-09 36.7 0.0 2.0 1 1 0 1 1 1 1 NLI interacting factor-like phosphatase NACHT PF05729.7 KLO07805.1 - 3.1e-16 59.4 0.6 1.4e-12 47.6 0.0 3.2 2 1 0 2 2 2 2 NACHT domain AAA_16 PF13191.1 KLO07805.1 - 9.8e-11 41.9 0.2 3.4e-05 23.9 0.0 4.0 3 1 0 3 3 3 2 AAA ATPase domain Arch_ATPase PF01637.13 KLO07805.1 - 9.5e-09 35.2 0.0 5.2e-06 26.3 0.0 2.6 2 0 0 2 2 2 2 Archaeal ATPase AAA_22 PF13401.1 KLO07805.1 - 1.4e-08 34.9 0.0 3.7e-05 23.8 0.0 2.9 2 0 0 2 2 2 2 AAA domain NB-ARC PF00931.17 KLO07805.1 - 3.2e-06 26.2 0.0 0.00028 19.8 0.0 2.6 3 0 0 3 3 3 1 NB-ARC domain AAA PF00004.24 KLO07805.1 - 2.1e-05 24.7 0.1 0.00095 19.3 0.0 3.2 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Parvo_NS1 PF01057.12 KLO07805.1 - 7.4e-05 21.7 1.0 0.074 11.9 0.1 2.3 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 AAA_17 PF13207.1 KLO07805.1 - 0.0025 18.6 0.6 0.23 12.2 0.3 3.7 3 1 0 3 3 3 1 AAA domain KAP_NTPase PF07693.9 KLO07805.1 - 0.0029 16.6 0.0 1.5 7.7 0.0 2.4 2 0 0 2 2 2 2 KAP family P-loop domain AAA_30 PF13604.1 KLO07805.1 - 0.0032 17.0 0.9 0.14 11.6 0.2 2.4 2 0 0 2 2 2 1 AAA domain APS_kinase PF01583.15 KLO07805.1 - 0.0046 16.6 1.7 0.098 12.3 0.2 2.4 2 0 0 2 2 2 1 Adenylylsulphate kinase Torsin PF06309.6 KLO07805.1 - 0.0057 16.5 0.0 6.5 6.6 0.0 3.2 3 0 0 3 3 3 1 Torsin AAA_19 PF13245.1 KLO07805.1 - 0.0069 16.1 0.2 0.082 12.6 0.0 2.8 3 0 0 3 3 2 1 Part of AAA domain RNA_helicase PF00910.17 KLO07805.1 - 0.017 15.2 0.3 1.3 9.2 0.1 2.8 2 0 0 2 2 2 0 RNA helicase AAA_18 PF13238.1 KLO07805.1 - 0.018 15.3 0.0 0.13 12.5 0.0 2.6 2 0 0 2 2 1 0 AAA domain MobB PF03205.9 KLO07805.1 - 0.024 14.3 0.1 3.9 7.1 0.1 2.6 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B NTPase_1 PF03266.10 KLO07805.1 - 0.11 12.1 0.0 17 5.0 0.0 2.5 2 0 0 2 2 2 0 NTPase PIF1 PF05970.9 KLO07805.1 - 0.19 10.6 0.0 1.2 8.0 0.0 2.0 2 0 0 2 2 2 0 PIF1-like helicase DAP3 PF10236.4 KLO07805.1 - 0.27 10.1 0.3 9.5 5.0 0.0 3.1 4 0 0 4 4 4 0 Mitochondrial ribosomal death-associated protein 3 Chitin_bind_4 PF00379.18 KLO07806.1 - 0.004 17.3 1.2 0.011 15.9 0.8 1.7 1 0 0 1 1 1 1 Insect cuticle protein NACHT PF05729.7 KLO07807.1 - 2.7e-16 59.6 0.2 8.3e-13 48.3 0.0 2.9 2 1 0 2 2 2 2 NACHT domain Pkinase PF00069.20 KLO07807.1 - 1.8e-13 50.2 0.0 3.1e-13 49.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KLO07807.1 - 4.5e-12 45.5 0.0 1e-11 44.4 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase AAA_16 PF13191.1 KLO07807.1 - 3.5e-11 43.4 0.5 1.7e-06 28.1 0.0 3.6 2 2 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.1 KLO07807.1 - 2.4e-09 37.4 0.0 2.1e-06 27.8 0.0 2.6 2 0 0 2 2 2 2 AAA domain NB-ARC PF00931.17 KLO07807.1 - 9.7e-05 21.3 0.0 0.0038 16.1 0.0 2.5 2 1 0 2 2 2 1 NB-ARC domain Parvo_NS1 PF01057.12 KLO07807.1 - 0.00015 20.7 1.2 0.34 9.7 0.0 2.3 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 AAA PF00004.24 KLO07807.1 - 0.00076 19.6 0.0 0.014 15.6 0.0 2.7 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) APS_kinase PF01583.15 KLO07807.1 - 0.0023 17.6 1.3 0.11 12.1 0.1 2.3 2 0 0 2 2 2 1 Adenylylsulphate kinase AAA_30 PF13604.1 KLO07807.1 - 0.003 17.1 0.5 0.12 11.9 0.4 2.4 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 KLO07807.1 - 0.0038 18.0 0.0 0.15 12.9 0.0 2.9 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 KLO07807.1 - 0.0042 16.8 0.1 0.067 12.9 0.1 2.6 2 0 0 2 2 2 1 Part of AAA domain AAA_18 PF13238.1 KLO07807.1 - 0.0047 17.2 0.0 0.29 11.4 0.0 3.2 3 0 0 3 3 3 1 AAA domain RNA_helicase PF00910.17 KLO07807.1 - 0.0081 16.3 0.1 0.86 9.8 0.0 2.8 2 0 0 2 2 2 1 RNA helicase KAP_NTPase PF07693.9 KLO07807.1 - 0.01 14.8 0.0 2.1 7.2 0.0 2.3 2 0 0 2 2 2 0 KAP family P-loop domain Torsin PF06309.6 KLO07807.1 - 0.021 14.7 0.0 4.3 7.2 0.0 2.7 2 0 0 2 2 2 0 Torsin PIF1 PF05970.9 KLO07807.1 - 0.032 13.1 0.0 0.24 10.3 0.0 2.1 2 0 0 2 2 2 0 PIF1-like helicase MobB PF03205.9 KLO07807.1 - 0.16 11.7 0.1 2.9 7.5 0.0 2.3 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B NACHT PF05729.7 KLO07808.1 - 2e-18 66.5 0.6 1.4e-12 47.6 0.0 3.4 2 1 0 2 2 2 2 NACHT domain AAA_16 PF13191.1 KLO07808.1 - 2e-13 50.7 0.7 6.4e-07 29.5 0.0 3.8 3 1 0 3 3 3 2 AAA ATPase domain AAA_22 PF13401.1 KLO07808.1 - 1.1e-10 41.7 0.0 2.9e-07 30.6 0.0 3.2 3 0 0 3 3 3 2 AAA domain AAA PF00004.24 KLO07808.1 - 9.4e-07 29.0 0.1 3.4e-05 24.0 0.0 3.0 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Parvo_NS1 PF01057.12 KLO07808.1 - 2.9e-05 23.0 1.0 0.15 10.9 0.0 2.3 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 NB-ARC PF00931.17 KLO07808.1 - 7.3e-05 21.7 0.1 0.00087 18.2 0.0 2.6 3 0 0 3 3 3 1 NB-ARC domain KAP_NTPase PF07693.9 KLO07808.1 - 9.6e-05 21.5 0.0 0.0028 16.7 0.0 2.3 2 0 0 2 2 2 1 KAP family P-loop domain AAA_30 PF13604.1 KLO07808.1 - 0.00059 19.4 0.0 0.053 13.0 0.0 2.5 2 0 0 2 2 2 1 AAA domain Torsin PF06309.6 KLO07808.1 - 0.0019 18.0 0.0 3.2 7.6 0.0 2.8 2 0 0 2 2 2 2 Torsin AAA_19 PF13245.1 KLO07808.1 - 0.0019 17.8 0.2 0.087 12.5 0.0 3.1 3 0 0 3 3 3 1 Part of AAA domain APS_kinase PF01583.15 KLO07808.1 - 0.0024 17.5 1.2 0.17 11.5 0.3 2.4 2 0 0 2 2 2 1 Adenylylsulphate kinase AAA_17 PF13207.1 KLO07808.1 - 0.0063 17.3 0.0 0.17 12.7 0.0 3.1 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.17 KLO07808.1 - 0.0082 16.3 0.3 1 9.5 0.0 3.0 3 0 0 3 3 2 1 RNA helicase AAA_18 PF13238.1 KLO07808.1 - 0.019 15.2 1.4 0.19 12.0 0.1 3.2 3 1 0 3 3 3 0 AAA domain DAP3 PF10236.4 KLO07808.1 - 0.046 12.6 0.0 6.4 5.6 0.0 3.1 3 0 0 3 3 3 0 Mitochondrial ribosomal death-associated protein 3 Ferritin PF00210.19 KLO07808.1 - 0.068 12.9 0.1 2.6 7.7 0.0 3.1 3 0 0 3 3 3 0 Ferritin-like domain PIF1 PF05970.9 KLO07808.1 - 0.071 12.0 0.0 1 8.2 0.0 2.1 2 0 0 2 2 2 0 PIF1-like helicase PhoH PF02562.11 KLO07808.1 - 0.095 11.9 0.0 6.1 6.0 0.0 2.5 2 0 0 2 2 2 0 PhoH-like protein DUF905 PF06006.7 KLO07808.1 - 0.14 11.5 0.0 0.31 10.4 0.0 1.5 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF905) Parvo_NS1 PF01057.12 KLO07809.1 - 0.034 13.0 0.0 0.035 12.9 0.0 1.0 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 NACHT PF05729.7 KLO07810.1 - 1.2e-13 51.0 0.0 4.6e-13 49.1 0.0 2.0 2 0 0 2 2 2 1 NACHT domain AAA_22 PF13401.1 KLO07810.1 - 1.5e-05 25.1 0.0 3.9e-05 23.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain NB-ARC PF00931.17 KLO07810.1 - 0.0019 17.1 0.0 0.0034 16.2 0.0 1.4 1 0 0 1 1 1 1 NB-ARC domain Parvo_NS1 PF01057.12 KLO07810.1 - 0.0041 16.0 0.1 0.0072 15.2 0.0 1.3 1 0 0 1 1 1 1 Parvovirus non-structural protein NS1 AAA_16 PF13191.1 KLO07810.1 - 0.0046 16.9 0.4 0.037 14.0 0.1 2.6 2 1 0 2 2 2 1 AAA ATPase domain RNA_helicase PF00910.17 KLO07810.1 - 0.024 14.7 0.0 0.063 13.4 0.0 1.8 1 0 0 1 1 1 0 RNA helicase PhoH PF02562.11 KLO07810.1 - 0.064 12.4 0.0 0.13 11.4 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein AAA_25 PF13481.1 KLO07810.1 - 0.069 12.5 0.1 0.27 10.6 0.0 2.0 2 0 0 2 2 2 0 AAA domain APS_kinase PF01583.15 KLO07810.1 - 0.1 12.2 0.0 0.2 11.3 0.0 1.5 1 0 0 1 1 1 0 Adenylylsulphate kinase NACHT PF05729.7 KLO07814.1 - 3.3e-16 59.3 0.5 2.5e-13 50.0 0.0 3.0 2 1 0 2 2 2 1 NACHT domain AAA_22 PF13401.1 KLO07814.1 - 4.5e-12 46.2 0.0 2.8e-06 27.5 0.0 3.0 3 0 0 3 3 2 2 AAA domain AAA_16 PF13191.1 KLO07814.1 - 3.1e-09 37.0 0.3 9.9e-06 25.6 0.0 3.5 2 1 0 2 2 2 2 AAA ATPase domain NB-ARC PF00931.17 KLO07814.1 - 3.4e-05 22.8 0.7 0.0023 16.8 0.0 3.3 3 1 0 3 3 3 1 NB-ARC domain Parvo_NS1 PF01057.12 KLO07814.1 - 0.00012 21.0 0.7 0.13 11.0 0.2 2.3 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 AAA PF00004.24 KLO07814.1 - 0.00089 19.4 0.0 0.016 15.4 0.0 2.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.1 KLO07814.1 - 0.0017 17.9 0.1 0.063 12.8 0.0 2.5 2 0 0 2 2 2 1 AAA domain APS_kinase PF01583.15 KLO07814.1 - 0.002 17.7 1.3 0.077 12.6 0.1 2.5 2 0 0 2 2 2 1 Adenylylsulphate kinase AAA_17 PF13207.1 KLO07814.1 - 0.0039 18.0 0.3 0.15 12.8 0.0 3.6 4 0 0 4 4 2 1 AAA domain AAA_19 PF13245.1 KLO07814.1 - 0.011 15.5 0.1 0.076 12.7 0.0 2.4 2 0 0 2 2 2 0 Part of AAA domain RNA_helicase PF00910.17 KLO07814.1 - 0.014 15.5 0.1 1.3 9.2 0.0 2.8 2 0 0 2 2 2 0 RNA helicase AAA_18 PF13238.1 KLO07814.1 - 0.016 15.5 0.1 0.2 11.9 0.0 3.0 3 0 0 3 3 2 0 AAA domain Torsin PF06309.6 KLO07814.1 - 0.019 14.8 0.0 12 5.8 0.0 2.9 2 0 0 2 2 2 0 Torsin PhoH PF02562.11 KLO07814.1 - 0.058 12.6 0.0 0.83 8.8 0.0 2.4 2 0 0 2 2 2 0 PhoH-like protein ABC_tran PF00005.22 KLO07814.1 - 0.083 13.1 0.0 0.29 11.4 0.0 1.9 1 0 0 1 1 1 0 ABC transporter AAA_33 PF13671.1 KLO07814.1 - 0.11 12.4 0.1 1.6 8.5 0.0 2.9 3 0 0 3 3 3 0 AAA domain PIF1 PF05970.9 KLO07814.1 - 0.14 11.0 0.0 0.49 9.2 0.0 1.8 2 0 0 2 2 2 0 PIF1-like helicase Abi PF02517.11 KLO07816.1 - 1.5e-13 50.6 3.5 1.5e-13 50.6 2.4 2.2 3 1 0 3 3 3 1 CAAX protease self-immunity LRR_4 PF12799.2 KLO07817.1 - 0.011 15.3 2.6 5.5 6.7 1.1 3.7 2 2 2 4 4 4 0 Leucine Rich repeats (2 copies) F-box-like PF12937.2 KLO07817.1 - 0.026 14.2 3.3 0.027 14.1 0.3 2.7 3 0 0 3 3 3 0 F-box-like DUF723 PF05265.8 KLO07817.1 - 0.096 12.5 0.0 2.3 8.0 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF723) NT-C2 PF10358.4 KLO07818.1 - 8.5e-21 73.9 0.0 6.2e-20 71.1 0.0 2.1 1 1 0 1 1 1 1 N-terminal C2 in EEIG1 and EHBP1 proteins Ribosomal_L28 PF00830.14 KLO07819.1 - 2.1e-23 81.8 0.4 2.9e-23 81.4 0.3 1.2 1 0 0 1 1 1 1 Ribosomal L28 family GWT1 PF06423.7 KLO07820.1 - 1.8e-37 128.4 2.5 2.1e-37 128.2 0.3 2.3 2 0 0 2 2 2 1 GWT1 Myb_DNA-binding PF00249.26 KLO07822.1 - 2.1e-06 27.7 0.0 4.4e-06 26.6 0.0 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain Spectrin PF00435.16 KLO07822.1 - 0.45 10.8 3.5 0.81 10.0 0.6 2.3 2 0 0 2 2 2 0 Spectrin repeat Polysacc_synt_4 PF04669.8 KLO07823.1 - 2.4e-23 82.4 1.8 1.8e-22 79.6 1.3 2.0 1 1 0 1 1 1 1 Polysaccharide biosynthesis Med30 PF11315.3 KLO07824.1 - 0.028 14.5 8.5 2.1 8.4 3.6 2.7 2 1 1 3 3 3 0 Mediator complex subunit 30 TFR_dimer PF04253.10 KLO07824.1 - 0.21 11.1 2.0 6.4 6.3 1.4 2.7 1 1 0 1 1 1 0 Transferrin receptor-like dimerisation domain DUF1825 PF08855.5 KLO07824.1 - 0.41 10.6 5.8 8.8 6.3 1.4 2.8 2 1 1 3 3 3 0 Domain of unknown function (DUF1825) ERM PF00769.14 KLO07824.1 - 2.9 7.3 27.1 10 5.5 18.8 1.7 1 1 0 1 1 1 0 Ezrin/radixin/moesin family GAS PF13851.1 KLO07824.1 - 4.8 6.3 16.5 13 4.9 11.4 1.6 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding Atg14 PF10186.4 KLO07824.1 - 6.2 5.6 16.3 11 4.9 11.3 1.3 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 GIY-YIG PF01541.19 KLO07825.1 - 4.9e-06 26.8 0.0 1e-05 25.7 0.0 1.5 1 0 0 1 1 1 1 GIY-YIG catalytic domain zf-RING_2 PF13639.1 KLO07825.1 - 0.016 15.0 5.1 0.028 14.2 3.5 1.4 1 0 0 1 1 1 0 Ring finger domain FANCL_C PF11793.3 KLO07825.1 - 0.088 12.7 1.3 0.21 11.5 0.9 1.6 1 0 0 1 1 1 0 FANCL C-terminal domain zf-RING-like PF08746.6 KLO07825.1 - 0.26 11.3 3.2 0.34 10.9 0.8 2.2 2 1 0 2 2 2 0 RING-like domain SAP PF02037.22 KLO07827.1 - 5.7e-08 32.0 0.9 1.7e-07 30.5 0.4 2.0 2 0 0 2 2 2 1 SAP domain LETM1 PF07766.8 KLO07827.1 - 0.27 10.2 0.2 0.42 9.5 0.2 1.2 1 0 0 1 1 1 0 LETM1-like protein Ribosomal_S30 PF04758.9 KLO07829.1 - 4.3e-26 90.4 5.5 4.7e-26 90.3 3.8 1.0 1 0 0 1 1 1 1 Ribosomal protein S30 Tropomyosin PF00261.15 KLO07830.1 - 1.1 8.3 6.6 0.049 12.7 0.7 1.5 2 0 0 2 2 2 0 Tropomyosin FMN_dh PF01070.13 KLO07831.1 - 1.1e-104 350.0 0.0 1.5e-104 349.7 0.0 1.0 1 0 0 1 1 1 1 FMN-dependent dehydrogenase NMO PF03060.10 KLO07831.1 - 9.1e-06 25.0 0.9 1.4e-05 24.3 0.6 1.2 1 0 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.20 KLO07831.1 - 3.1e-05 23.0 0.5 0.00012 21.1 0.1 2.0 1 1 1 2 2 2 1 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.12 KLO07831.1 - 0.00015 20.7 0.1 0.00023 20.2 0.1 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase His_biosynth PF00977.16 KLO07831.1 - 0.0025 17.1 0.4 0.73 9.0 0.0 2.2 1 1 1 2 2 2 2 Histidine biosynthesis protein ThiG PF05690.9 KLO07831.1 - 0.0047 16.0 0.6 1.7 7.6 0.0 2.4 1 1 1 2 2 2 2 Thiazole biosynthesis protein ThiG DHO_dh PF01180.16 KLO07831.1 - 0.005 15.8 0.5 0.01 14.8 0.0 1.8 2 1 1 3 3 3 1 Dihydroorotate dehydrogenase PcrB PF01884.12 KLO07831.1 - 0.043 13.0 0.7 1.3 8.1 0.0 2.2 1 1 1 2 2 2 0 PcrB family Pterin_bind PF00809.17 KLO07834.1 - 1.5e-50 171.4 0.0 3.3e-50 170.3 0.0 1.6 1 0 0 1 1 1 1 Pterin binding enzyme HPPK PF01288.15 KLO07834.1 - 2.8e-30 104.6 0.0 1.4e-28 99.1 0.0 2.4 1 1 0 1 1 1 1 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) FolB PF02152.13 KLO07834.1 - 4.3e-25 88.0 0.0 2.2e-14 53.5 0.0 2.5 2 0 0 2 2 2 2 Dihydroneopterin aldolase HIG_1_N PF04588.8 KLO07835.1 - 9.7e-17 60.4 1.1 1.4e-16 59.9 0.7 1.3 1 0 0 1 1 1 1 Hypoxia induced protein conserved region DHH PF01368.15 KLO07836.1 - 5.2e-12 45.6 0.0 1e-11 44.6 0.0 1.5 1 0 0 1 1 1 1 DHH family DHHA2 PF02833.9 KLO07836.1 - 4.6e-10 39.7 0.1 2.6e-09 37.3 0.1 2.3 2 1 0 2 2 2 1 DHHA2 domain TPR_14 PF13428.1 KLO07837.1 - 1.1e-10 41.1 2.5 0.0032 17.9 0.2 4.8 1 1 4 5 5 5 3 Tetratricopeptide repeat TPR_11 PF13414.1 KLO07837.1 - 2.1e-09 36.9 0.5 3.7e-05 23.2 0.0 2.7 2 0 0 2 2 2 2 TPR repeat TPR_16 PF13432.1 KLO07837.1 - 1.1e-08 35.4 2.2 0.001 19.6 0.1 3.7 2 1 2 4 4 4 3 Tetratricopeptide repeat TPR_8 PF13181.1 KLO07837.1 - 6.8e-08 31.7 0.8 0.00022 20.7 0.0 4.3 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_2 PF07719.12 KLO07837.1 - 8.5e-08 31.5 0.7 0.00066 19.4 0.1 4.6 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_1 PF00515.23 KLO07837.1 - 5.9e-07 28.8 0.2 0.0033 16.9 0.0 4.2 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_19 PF14559.1 KLO07837.1 - 9.1e-07 29.1 3.3 0.00039 20.6 0.1 3.0 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_9 PF13371.1 KLO07837.1 - 5.9e-05 22.8 2.3 0.089 12.6 0.2 2.7 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.1 KLO07837.1 - 6.1e-05 22.5 0.5 0.0082 15.8 0.0 3.0 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.1 KLO07837.1 - 0.0005 19.9 2.5 0.087 12.7 0.0 3.4 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.1 KLO07837.1 - 0.0097 16.0 1.6 11 6.4 0.0 3.9 5 0 0 5 5 4 0 Tetratricopeptide repeat APP_E2 PF12925.2 KLO07837.1 - 0.031 13.8 0.0 0.063 12.8 0.0 1.5 1 0 0 1 1 1 0 E2 domain of amyloid precursor protein TPR_15 PF13429.1 KLO07837.1 - 0.046 12.7 1.7 0.15 11.0 1.1 1.7 1 1 0 1 1 1 0 Tetratricopeptide repeat TPR_6 PF13174.1 KLO07837.1 - 0.06 13.8 1.2 18 6.0 0.0 4.7 6 0 0 6 6 5 0 Tetratricopeptide repeat CotJB PF12652.2 KLO07837.1 - 0.6 10.2 2.6 17 5.5 0.0 2.9 2 1 1 3 3 3 0 CotJB protein Complex1_LYR_1 PF13232.1 KLO07838.1 - 5.6e-10 39.2 1.9 7e-10 38.9 1.3 1.1 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.10 KLO07838.1 - 1e-09 38.0 1.6 1.3e-09 37.6 1.1 1.2 1 0 0 1 1 1 1 Complex 1 protein (LYR family) DUF1386 PF07138.6 KLO07838.1 - 0.08 12.0 0.2 0.09 11.8 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1386) Peptidase_S24 PF00717.18 KLO07840.1 - 2.2e-08 33.6 0.1 3.8e-08 32.8 0.0 1.3 1 0 0 1 1 1 1 Peptidase S24-like DUF950 PF06106.6 KLO07840.1 - 0.11 12.5 0.0 0.14 12.1 0.0 1.3 1 0 0 1 1 1 0 Staphylococcus protein of unknown function (DUF950) Zn_clus PF00172.13 KLO07843.1 - 0.00037 20.3 9.0 0.00068 19.5 6.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Git3 PF11710.3 KLO07844.1 - 3.2e-08 33.3 6.3 8.6e-08 31.9 4.3 1.6 1 1 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 7tm_1 PF00001.16 KLO07844.1 - 5.4e-05 22.4 3.7 7e-05 22.0 1.7 1.9 1 1 1 2 2 2 1 7 transmembrane receptor (rhodopsin family) DUF1691 PF07950.6 KLO07844.1 - 0.064 13.1 1.0 0.24 11.3 0.1 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF1691) Git3_C PF11970.3 KLO07844.1 - 0.18 11.5 0.1 0.18 11.5 0.0 2.3 2 0 0 2 2 2 0 G protein-coupled glucose receptor regulating Gpa2 C-term Zn_clus PF00172.13 KLO07845.1 - 0.00067 19.5 5.4 0.0012 18.7 3.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Zn_clus PF00172.13 KLO07846.1 - 0.0024 17.7 5.5 0.0036 17.1 3.8 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Git3 PF11710.3 KLO07848.1 - 8e-07 28.8 10.0 2.6e-06 27.1 7.0 1.7 1 1 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 7tm_1 PF00001.16 KLO07848.1 - 1.6e-05 24.1 5.8 1.9e-05 23.9 3.5 1.6 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) ABC2_membrane_2 PF12679.2 KLO07848.1 - 0.0069 15.2 0.4 0.0069 15.2 0.3 1.6 2 0 0 2 2 2 1 ABC-2 family transporter protein Frag1 PF10277.4 KLO07849.1 - 6.4e-44 150.0 7.2 7.2e-44 149.8 5.0 1.0 1 0 0 1 1 1 1 Frag1/DRAM/Sfk1 family DUF998 PF06197.8 KLO07849.1 - 2.1e-05 23.8 18.6 0.00013 21.3 12.9 2.1 1 1 0 1 1 1 1 Protein of unknown function (DUF998) DUF4064 PF13273.1 KLO07849.1 - 0.0019 18.2 5.1 0.0019 18.2 3.5 2.5 2 2 0 2 2 2 1 Protein of unknown function (DUF4064) DUF1294 PF06961.8 KLO07849.1 - 0.074 13.0 1.8 0.079 12.9 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1294) DUF1129 PF06570.6 KLO07849.1 - 0.94 8.7 3.9 1.3 8.2 2.3 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1129) Peptidase_U4 PF03419.8 KLO07849.1 - 0.95 8.4 4.1 1.3 8.0 2.9 1.2 1 0 0 1 1 1 0 Sporulation factor SpoIIGA DUF3754 PF12576.3 KLO07849.1 - 0.96 9.0 3.4 1.1 8.9 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3754) Tetraspannin PF00335.15 KLO07849.1 - 6.9 5.8 14.5 19 4.4 9.1 2.0 1 1 1 2 2 2 0 Tetraspanin family Git3 PF11710.3 KLO07850.1 - 2e-06 27.4 5.8 5e-06 26.2 4.0 1.6 1 0 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 7tm_1 PF00001.16 KLO07850.1 - 0.00052 19.2 4.2 0.00079 18.6 2.6 1.6 1 1 1 2 2 2 1 7 transmembrane receptor (rhodopsin family) Citrate_synt PF00285.16 KLO07851.1 - 2.3e-102 342.4 0.0 2.8e-102 342.1 0.0 1.1 1 0 0 1 1 1 1 Citrate synthase Glyco_hydro_98M PF08306.6 KLO07851.1 - 0.094 11.4 0.0 0.15 10.7 0.0 1.3 1 0 0 1 1 1 0 Glycosyl hydrolase family 98 CoA_trans PF01144.18 KLO07852.1 - 8.8e-97 322.5 1.9 3.2e-56 189.9 0.1 2.0 2 0 0 2 2 2 2 Coenzyme A transferase AcetylCoA_hyd_C PF13336.1 KLO07852.1 - 6.7e-05 22.6 0.3 0.00018 21.2 0.1 1.8 2 0 0 2 2 2 1 Acetyl-CoA hydrolase/transferase C-terminal domain AcetylCoA_hydro PF02550.10 KLO07852.1 - 0.047 13.4 0.2 6.3 6.4 0.0 3.4 4 0 0 4 4 4 0 Acetyl-CoA hydrolase/transferase N-terminal domain CoA_trans PF01144.18 KLO07853.1 - 1.7e-100 334.6 5.8 6.8e-60 201.9 0.6 2.0 2 0 0 2 2 2 2 Coenzyme A transferase AcetylCoA_hyd_C PF13336.1 KLO07853.1 - 0.00032 20.4 0.0 0.00064 19.4 0.0 1.4 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase C-terminal domain AcetylCoA_hydro PF02550.10 KLO07853.1 - 0.026 14.2 0.0 1.5 8.5 0.0 3.0 3 0 0 3 3 3 0 Acetyl-CoA hydrolase/transferase N-terminal domain DeoRC PF00455.17 KLO07853.1 - 0.078 12.6 0.0 3.1 7.4 0.0 2.5 2 0 0 2 2 2 0 DeoR C terminal sensor domain F-box-like PF12937.2 KLO07857.1 - 1.6e-08 34.1 0.5 4.6e-08 32.6 0.3 1.9 1 0 0 1 1 1 1 F-box-like F-box-like PF12937.2 KLO07858.1 - 1e-08 34.7 1.6 2.7e-08 33.4 1.1 1.8 1 0 0 1 1 1 1 F-box-like F-box-like_2 PF13013.1 KLO07858.1 - 0.071 12.8 0.1 0.22 11.2 0.1 1.8 1 0 0 1 1 1 0 F-box-like domain F-box-like PF12937.2 KLO07859.1 - 1.5e-08 34.2 0.4 1.5e-08 34.2 0.3 2.1 2 0 0 2 2 2 1 F-box-like F-box-like_2 PF13013.1 KLO07859.1 - 0.12 12.0 1.2 1.8 8.3 0.1 3.0 2 1 0 2 2 2 0 F-box-like domain Gln-synt_C PF00120.19 KLO07860.1 - 3.6e-49 167.2 0.0 4.6e-49 166.8 0.0 1.1 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain DUF1956 PF09209.6 KLO07860.1 - 0.16 11.9 0.0 0.3 11.0 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1956) BTB PF00651.26 KLO07862.1 - 0.0029 17.5 0.0 0.0066 16.4 0.0 1.5 1 1 0 1 1 1 1 BTB/POZ domain NYD-SP28_assoc PF14775.1 KLO07862.1 - 0.066 12.9 0.2 0.13 11.9 0.2 1.5 1 0 0 1 1 1 0 Sperm tail C-terminal domain DUF4182 PF13790.1 KLO07862.1 - 0.14 11.9 0.4 0.34 10.7 0.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4182) DUF1451 PF07295.6 KLO07862.1 - 1.5 8.6 3.9 4.4 7.0 0.1 2.9 3 1 0 3 3 3 0 Protein of unknown function (DUF1451) DUF2356 PF10189.4 KLO07867.1 - 0.035 13.1 0.1 4 6.4 0.0 2.4 2 0 0 2 2 2 0 Conserved protein (DUF2356) Pes-10 PF07149.6 KLO07867.1 - 0.082 11.6 0.1 2.3 6.9 0.0 2.1 1 1 1 2 2 2 0 Pes-10 Synuclein PF01387.12 KLO07869.1 - 0.091 12.6 0.1 0.18 11.7 0.0 1.5 1 0 0 1 1 1 0 Synuclein SCP1201-deam PF14428.1 KLO07869.1 - 0.72 9.5 3.8 0.44 10.2 0.2 1.9 2 0 0 2 2 2 0 SCP1.201-like deaminase RNase_H PF00075.19 KLO07874.1 - 0.0064 16.8 0.0 0.0066 16.7 0.0 1.0 1 0 0 1 1 1 1 RNase H Aldo_ket_red PF00248.16 KLO07878.1 - 6.4e-70 235.1 0.0 7.4e-70 234.9 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family zf-DBF PF07535.7 KLO07880.1 - 7.1e-15 54.4 2.1 1.4e-14 53.5 1.5 1.4 1 0 0 1 1 1 1 DBF zinc finger Dfp1_Him1_M PF08630.5 KLO07880.1 - 1.4e-11 44.2 0.0 3e-11 43.1 0.0 1.5 1 0 0 1 1 1 1 Dfp1/Him1, central region BRCT PF00533.21 KLO07880.1 - 1.6e-05 24.9 0.0 3.8e-05 23.7 0.0 1.7 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.2 KLO07880.1 - 0.019 14.8 0.0 0.037 13.8 0.0 1.4 1 0 0 1 1 1 0 twin BRCT domain Pkinase PF00069.20 KLO07885.1 - 1.1e-24 87.0 0.0 1.2e-24 86.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KLO07885.1 - 3.6e-22 78.6 0.0 4e-22 78.5 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 KLO07885.1 - 0.002 17.2 0.0 0.0024 16.9 0.0 1.1 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KLO07885.1 - 0.0078 15.9 0.0 0.0093 15.7 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.1 KLO07885.1 - 0.043 12.7 0.0 0.048 12.6 0.0 1.1 1 0 0 1 1 1 0 Kinase-like F-box-like PF12937.2 KLO07887.1 - 2.9e-05 23.6 0.2 2.9e-05 23.6 0.2 2.0 2 0 0 2 2 2 1 F-box-like F-box-like PF12937.2 KLO07889.1 - 0.00018 21.1 2.4 0.00027 20.5 0.2 2.3 2 0 0 2 2 2 1 F-box-like LRR_4 PF12799.2 KLO07889.1 - 0.058 13.0 0.3 29 4.4 0.0 3.6 2 1 0 2 2 2 0 Leucine Rich repeats (2 copies) F-box PF00646.28 KLO07889.1 - 0.14 11.8 1.7 0.37 10.4 0.1 2.6 2 0 0 2 2 2 0 F-box domain LRR_8 PF13855.1 KLO07889.1 - 0.46 10.2 2.5 53 3.6 0.2 4.1 4 1 0 4 4 4 0 Leucine rich repeat Asp PF00026.18 KLO07895.1 - 1.8e-11 43.8 0.0 6.6e-06 25.5 0.0 2.1 2 0 0 2 2 2 2 Eukaryotic aspartyl protease zf-U1 PF06220.7 KLO07898.1 - 5.4e-18 64.2 4.3 8.1e-18 63.7 3.0 1.3 1 0 0 1 1 1 1 U1 zinc finger zf-C2H2_jaz PF12171.3 KLO07898.1 - 1.9e-06 27.7 2.2 2.9e-06 27.2 1.6 1.3 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 KLO07898.1 - 1.4 9.2 3.8 19 5.6 2.7 2.2 1 1 0 1 1 1 0 Zinc-finger of C2H2 type Methyltransf_23 PF13489.1 KLO07900.1 - 2.6e-07 30.4 0.0 4.1e-07 29.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KLO07900.1 - 2.9e-06 27.6 0.0 6.1e-06 26.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KLO07900.1 - 7.2e-06 25.6 0.0 1.3e-05 24.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KLO07900.1 - 1.3e-05 25.6 0.0 2.8e-05 24.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_29 PF03141.11 KLO07900.1 - 0.003 15.9 0.0 0.0051 15.1 0.0 1.3 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Ubie_methyltran PF01209.13 KLO07900.1 - 0.0072 15.4 0.0 0.011 14.9 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_18 PF12847.2 KLO07900.1 - 0.083 13.4 0.0 0.23 12.0 0.0 1.9 1 1 0 1 1 1 0 Methyltransferase domain Peptidase_M48 PF01435.13 KLO07901.1 - 0.024 14.2 0.0 0.03 13.8 0.0 1.2 1 0 0 1 1 1 0 Peptidase family M48 14-3-3 PF00244.15 KLO07903.1 - 3.2e-83 278.4 1.1 3.6e-83 278.2 0.8 1.0 1 0 0 1 1 1 1 14-3-3 protein DUF1943 PF09172.6 KLO07903.1 - 0.12 11.1 0.0 0.14 10.9 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1943) SSV1_ORF_D-335 PF07935.6 KLO07903.1 - 0.13 12.0 0.5 1.3 8.7 0.1 2.2 2 0 0 2 2 2 0 ORF D-335-like protein DUF1041 PF06292.12 KLO07904.1 - 0.078 13.1 0.4 7.3 6.8 0.0 2.2 1 1 1 2 2 2 0 Domain of Unknown Function (DUF1041) DALR_1 PF05746.10 KLO07904.1 - 0.2 11.6 1.2 5.7 6.9 0.8 2.1 1 1 0 1 1 1 0 DALR anticodon binding domain RRM_3 PF08777.6 KLO07908.1 - 8.2e-08 32.0 0.0 3.5e-07 30.0 0.0 1.9 1 1 0 1 1 1 1 RNA binding motif RRM_6 PF14259.1 KLO07908.1 - 4.4e-05 23.3 0.0 0.13 12.2 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 KLO07908.1 - 0.008 15.7 0.1 0.2 11.3 0.0 2.5 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF1768 PF08719.6 KLO07909.1 - 1.3e-23 83.4 0.0 1.5e-23 83.2 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1768) SAP18 PF06487.7 KLO07910.1 - 4.8e-25 87.7 0.0 6.1e-25 87.3 0.0 1.1 1 0 0 1 1 1 1 Sin3 associated polypeptide p18 (SAP18) Dicer_dimer PF03368.9 KLO07910.1 - 0.084 12.6 0.0 0.15 11.8 0.0 1.4 1 0 0 1 1 1 0 Dicer dimerisation domain WD40 PF00400.27 KLO07911.1 - 1.5e-43 145.1 4.7 3.9e-08 32.8 0.0 7.5 7 0 0 7 7 7 7 WD domain, G-beta repeat Lactonase PF10282.4 KLO07911.1 - 0.066 12.2 0.0 0.14 11.1 0.0 1.5 1 1 0 1 1 1 0 Lactonase, 7-bladed beta-propeller PQQ_3 PF13570.1 KLO07911.1 - 0.51 10.6 8.8 0.81 10.0 0.0 3.8 5 0 0 5 5 5 0 PQQ-like domain Herpes_US9 PF06072.6 KLO07912.1 - 0.081 12.7 0.3 0.23 11.3 0.2 1.8 1 0 0 1 1 1 0 Alphaherpesvirus tegument protein US9 SSF PF00474.12 KLO07914.1 - 2.7e-22 78.9 24.4 3.7e-22 78.5 16.9 1.2 1 0 0 1 1 1 1 Sodium:solute symporter family Lipoprotein_9 PF03180.9 KLO07915.1 - 0.21 10.4 0.0 2.7 6.8 0.0 2.1 2 0 0 2 2 2 0 NLPA lipoprotein F-box-like PF12937.2 KLO07916.1 - 1.2e-06 28.1 0.2 4.6e-06 26.2 0.1 2.1 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 KLO07916.1 - 0.015 14.8 0.2 0.066 12.8 0.1 2.1 1 1 0 1 1 1 0 F-box domain FeS PF04060.8 KLO07916.1 - 0.089 12.3 0.4 0.28 10.8 0.3 1.8 1 0 0 1 1 1 0 Putative Fe-S cluster F-box-like PF12937.2 KLO07917.1 - 0.00071 19.2 0.1 0.0021 17.7 0.1 1.9 1 0 0 1 1 1 1 F-box-like Bacteriocin_IIc PF10439.4 KLO07918.1 - 7.3 6.7 12.8 9.8 6.3 8.9 1.2 1 0 0 1 1 1 0 Bacteriocin class II with double-glycine leader peptide Acetyltransf_1 PF00583.19 KLO07919.1 - 1.7e-14 53.6 0.1 2.3e-14 53.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_9 PF13527.1 KLO07919.1 - 0.00016 21.5 0.1 0.00018 21.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 KLO07919.1 - 0.00017 21.6 0.0 0.00021 21.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 KLO07919.1 - 0.00021 20.9 0.1 0.00029 20.5 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_7 PF13508.1 KLO07919.1 - 0.00026 21.0 0.2 0.00044 20.3 0.0 1.4 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 KLO07919.1 - 0.04 14.0 0.0 0.045 13.9 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Abhydrolase_6 PF12697.2 KLO07920.1 - 2.1e-07 31.0 0.4 3.1e-07 30.5 0.3 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF676 PF05057.9 KLO07920.1 - 4.4e-06 26.1 0.0 9.1e-06 25.1 0.0 1.4 2 0 0 2 2 2 1 Putative serine esterase (DUF676) Abhydrolase_5 PF12695.2 KLO07920.1 - 1.7e-05 24.5 0.1 3.3e-05 23.6 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.8 KLO07920.1 - 0.002 17.7 0.2 0.005 16.4 0.1 1.7 1 1 0 1 1 1 1 PGAP1-like protein Chlorophyllase2 PF12740.2 KLO07920.1 - 0.0034 16.3 0.0 0.0052 15.7 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase enzyme Lipase_3 PF01764.20 KLO07920.1 - 0.006 16.2 0.0 0.0098 15.5 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) DUF1992 PF09350.5 KLO07921.1 - 1.6e-19 69.5 0.0 3.7e-19 68.2 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1992) DUF4139 PF13598.1 KLO07921.1 - 0.055 12.7 4.0 0.082 12.2 1.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4139) Pro_isomerase PF00160.16 KLO07923.1 - 4.6e-36 124.3 0.0 7.7e-36 123.6 0.0 1.4 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD RRM_1 PF00076.17 KLO07923.1 - 1e-16 60.2 0.0 1.9e-16 59.4 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KLO07923.1 - 5.1e-13 48.7 0.0 1.5e-12 47.3 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KLO07923.1 - 2.6e-09 36.7 0.0 5.9e-09 35.6 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) F-box-like PF12937.2 KLO07924.1 - 0.00084 19.0 0.3 0.002 17.8 0.2 1.6 1 0 0 1 1 1 1 F-box-like F-box-like PF12937.2 KLO07925.1 - 3e-06 26.8 0.0 7.4e-06 25.5 0.0 1.7 1 0 0 1 1 1 1 F-box-like p450 PF00067.17 KLO07927.1 - 3.6e-52 177.4 0.0 4.9e-52 176.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 KLO07928.1 - 4.1e-62 210.2 0.0 5.1e-62 209.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Terpene_synth_C PF03936.11 KLO07930.1 - 3.9e-09 36.1 0.0 6.3e-09 35.4 0.0 1.4 1 1 0 1 1 1 1 Terpene synthase family, metal binding domain p450 PF00067.17 KLO07931.1 - 3.2e-70 236.9 0.0 4e-70 236.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 F-box-like PF12937.2 KLO07932.1 - 6.6e-07 28.9 1.9 2.3e-06 27.2 0.3 2.4 2 0 0 2 2 2 1 F-box-like F-box-like PF12937.2 KLO07933.1 - 0.00012 21.7 0.3 0.00012 21.7 0.2 2.4 2 0 0 2 2 2 1 F-box-like F-box-like PF12937.2 KLO07934.1 - 1.8e-06 27.5 0.9 1.8e-06 27.5 0.6 2.6 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 KLO07934.1 - 0.017 14.7 1.9 0.12 12.0 1.3 2.5 1 1 0 1 1 1 0 F-box domain F-box-like PF12937.2 KLO07935.1 - 1.3e-05 24.7 1.0 1.3e-05 24.7 0.7 2.7 3 0 0 3 3 3 1 F-box-like YEATS PF03366.11 KLO07936.1 - 0.027 14.1 0.0 0.055 13.1 0.0 1.4 1 0 0 1 1 1 0 YEATS family SOBP PF15279.1 KLO07937.1 - 2.2 8.5 21.6 3.1 8.1 15.0 1.2 1 0 0 1 1 1 0 Sine oculis-binding protein Menin PF05053.8 KLO07937.1 - 3.4 5.7 7.5 5.3 5.0 5.2 1.2 1 0 0 1 1 1 0 Menin Epimerase PF01370.16 KLO07940.1 - 1.3e-09 37.8 0.0 2.7e-09 36.8 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 KLO07940.1 - 2.4e-05 24.3 0.6 5.1e-05 23.3 0.4 1.6 1 1 0 1 1 1 1 NADH(P)-binding Saccharop_dh PF03435.13 KLO07940.1 - 0.0008 18.4 0.1 0.0013 17.7 0.0 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase NmrA PF05368.8 KLO07940.1 - 0.006 15.8 0.1 0.011 14.9 0.1 1.5 1 0 0 1 1 1 1 NmrA-like family Semialdhyde_dh PF01118.19 KLO07940.1 - 0.006 16.8 0.0 0.011 15.9 0.0 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain TrkA_N PF02254.13 KLO07940.1 - 0.008 16.1 0.0 0.016 15.2 0.0 1.5 1 0 0 1 1 1 1 TrkA-N domain 3Beta_HSD PF01073.14 KLO07940.1 - 0.053 12.2 0.1 1.8 7.2 0.0 2.1 2 0 0 2 2 2 0 3-beta hydroxysteroid dehydrogenase/isomerase family DUF4170 PF13773.1 KLO07941.1 - 0.083 12.8 0.0 0.22 11.4 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4170) p450 PF00067.17 KLO07942.1 - 2.7e-53 181.1 0.0 3.4e-53 180.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Peptidase_C48 PF02902.14 KLO07946.1 - 6.9e-14 51.9 1.1 1.1e-13 51.3 0.7 1.2 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain Tet_JBP PF12851.2 KLO07948.1 - 3.7e-13 49.1 0.0 8.5e-13 47.9 0.0 1.6 2 0 0 2 2 2 1 Oxygenase domain of the 2OGFeDO superfamily DUF3580 PF12117.3 KLO07948.1 - 0.015 15.2 0.0 0.043 13.7 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3580) Alpha_kinase PF02816.13 KLO07949.1 - 0.00012 21.8 0.0 0.00012 21.7 0.0 1.1 1 0 0 1 1 1 1 Alpha-kinase family ADH_zinc_N PF00107.21 KLO07952.1 - 4.6e-19 68.2 0.2 7.8e-19 67.5 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KLO07952.1 - 5e-12 45.5 0.0 1.5e-11 43.9 0.0 1.7 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 KLO07952.1 - 8.1e-09 36.4 0.0 1.7e-08 35.4 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase S10_plectin PF03501.10 KLO07953.1 - 1.7e-38 130.3 0.1 2e-38 130.1 0.1 1.1 1 0 0 1 1 1 1 Plectin/S10 domain F-box PF00646.28 KLO07954.1 - 0.5 10.1 3.5 0.6 9.8 0.8 2.2 2 0 0 2 2 2 0 F-box domain TEX19 PF15553.1 KLO07954.1 - 1.9 8.3 5.2 4.7 7.0 3.6 1.6 1 0 0 1 1 1 0 Testis-expressed protein 19 HSP20 PF00011.16 KLO07955.1 - 0.00022 21.0 0.0 0.00091 19.0 0.0 1.8 1 1 0 1 1 1 1 Hsp20/alpha crystallin family PEGA PF08308.6 KLO07955.1 - 0.042 13.6 0.0 0.077 12.7 0.0 1.4 1 0 0 1 1 1 0 PEGA domain Defensin_beta_2 PF13841.1 KLO07956.1 - 0.037 14.3 0.7 0.037 14.3 0.5 3.4 3 1 0 3 3 3 0 Beta defensin IFNGR1 PF07140.6 KLO07956.1 - 0.061 13.0 4.0 0.038 13.7 1.3 1.7 1 1 1 2 2 2 0 Interferon gamma receptor (IFNGR1) AAA PF00004.24 KLO07957.1 - 1.7e-14 54.1 0.0 3.3e-14 53.2 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) BAH PF01426.13 KLO07957.1 - 6.4e-12 45.2 0.1 1.4e-11 44.2 0.1 1.5 1 0 0 1 1 1 1 BAH domain AAA_16 PF13191.1 KLO07957.1 - 2e-08 34.4 0.0 1e-07 32.1 0.0 2.1 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 KLO07957.1 - 2.2e-07 31.0 0.0 4.7e-07 29.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain DUF2075 PF09848.4 KLO07957.1 - 0.00076 18.5 0.0 0.0031 16.5 0.0 1.8 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) AAA_19 PF13245.1 KLO07957.1 - 0.0014 18.3 0.0 0.0014 18.3 0.0 2.6 3 0 0 3 3 3 1 Part of AAA domain Arch_ATPase PF01637.13 KLO07957.1 - 0.0039 16.9 0.0 0.013 15.1 0.0 1.9 1 1 0 1 1 1 1 Archaeal ATPase AAA_11 PF13086.1 KLO07957.1 - 0.035 13.6 0.0 0.077 12.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain Nop14 PF04147.7 KLO07957.1 - 0.052 11.4 12.6 0.081 10.8 8.7 1.2 1 0 0 1 1 1 0 Nop14-like family NTPase_1 PF03266.10 KLO07957.1 - 0.053 13.2 0.0 0.12 12.0 0.0 1.6 1 0 0 1 1 1 0 NTPase NACHT PF05729.7 KLO07957.1 - 0.059 13.0 0.0 0.2 11.2 0.0 1.9 1 1 0 1 1 1 0 NACHT domain Miro PF08477.8 KLO07957.1 - 0.086 13.3 0.2 0.35 11.3 0.0 2.0 2 0 0 2 2 2 0 Miro-like protein CDC45 PF02724.9 KLO07957.1 - 3.4 5.5 11.6 5.2 4.9 8.0 1.2 1 0 0 1 1 1 0 CDC45-like protein Aminotran_1_2 PF00155.16 KLO07959.1 - 3.2e-27 95.4 0.0 3.9e-27 95.1 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.2 KLO07959.1 - 1e-05 24.3 0.0 1.5e-05 23.7 0.0 1.1 1 0 0 1 1 1 1 Alanine-glyoxylate amino-transferase Ribosomal_S21 PF01165.15 KLO07959.1 - 0.074 12.5 0.1 0.2 11.1 0.1 1.7 1 0 0 1 1 1 0 Ribosomal protein S21 PPI_Ypi1 PF07491.6 KLO07960.1 - 3.7e-26 90.5 1.4 3.7e-26 90.5 1.0 2.7 2 1 0 2 2 2 1 Protein phosphatase inhibitor Zip PF02535.17 KLO07960.1 - 1.2 8.0 4.2 1.7 7.5 2.9 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter DUF2415 PF10313.4 KLO07961.1 - 2.6e-09 36.5 0.4 6.3e-09 35.3 0.3 1.7 1 0 0 1 1 1 1 Uncharacterised protein domain (DUF2415) WD40 PF00400.27 KLO07961.1 - 7.3e-06 25.6 10.4 0.22 11.4 0.2 5.8 5 1 1 6 6 6 2 WD domain, G-beta repeat zf-met PF12874.2 KLO07962.1 - 1.4e-06 28.2 15.6 0.1 12.8 0.0 5.5 5 0 0 5 5 5 3 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 KLO07962.1 - 6.8e-06 26.0 10.9 0.19 11.9 0.0 4.7 3 1 1 4 4 4 3 Zinc-finger double-stranded RNA-binding zf-RING_5 PF14634.1 KLO07962.1 - 8.7e-05 22.1 12.2 8.7e-05 22.1 8.5 3.7 2 1 1 3 3 3 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 KLO07962.1 - 0.00023 21.1 12.5 0.00023 21.1 8.7 3.6 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KLO07962.1 - 0.00024 20.6 11.2 0.00024 20.6 7.8 3.0 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KLO07962.1 - 0.00067 19.4 13.1 0.00067 19.4 9.1 2.8 2 1 0 2 2 2 1 Ring finger domain zf-C3HC4 PF00097.20 KLO07962.1 - 0.0008 19.0 12.5 0.0008 19.0 8.6 3.3 2 1 1 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.1 KLO07962.1 - 0.02 14.6 7.2 0.055 13.2 5.0 1.7 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-C2H2_4 PF13894.1 KLO07962.1 - 0.042 14.1 1.2 0.042 14.1 0.8 5.8 6 0 0 6 6 6 0 C2H2-type zinc finger zf-C2H2_2 PF12756.2 KLO07962.1 - 2.5 8.2 15.5 0.044 13.8 2.9 3.1 2 1 1 3 3 3 0 C2H2 type zinc-finger (2 copies) DUF2628 PF10947.3 KLO07963.1 - 0.031 14.0 0.9 0.036 13.8 0.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2628) Frankia_peptide PF14407.1 KLO07963.1 - 0.067 12.9 0.0 0.1 12.3 0.0 1.3 1 0 0 1 1 1 0 Ribosomally synthesized peptide prototyped by Frankia Franean1_4349. DUF2207 PF09972.4 KLO07963.1 - 0.09 11.3 0.4 0.099 11.2 0.3 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF4131 PF13567.1 KLO07963.1 - 3.5 6.9 9.7 5.3 6.4 6.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) Vma12 PF11712.3 KLO07963.1 - 9.8 5.8 10.6 11 5.6 0.2 2.4 2 1 0 2 2 2 0 Endoplasmic reticulum-based factor for assembly of V-ATPase F-box-like PF12937.2 KLO07964.1 - 0.11 12.1 0.4 0.22 11.2 0.3 1.5 1 0 0 1 1 1 0 F-box-like Nop14 PF04147.7 KLO07966.1 - 0.0054 14.7 0.5 0.0073 14.2 0.3 1.2 1 0 0 1 1 1 1 Nop14-like family CENP-B_dimeris PF09026.5 KLO07966.1 - 3.9 7.7 15.4 48 4.2 10.1 2.5 2 0 0 2 2 2 0 Centromere protein B dimerisation domain Nucleoplasmin PF03066.10 KLO07966.1 - 5.4 6.5 9.8 15 5.1 6.8 1.7 1 0 0 1 1 1 0 Nucleoplasmin SWIM PF04434.12 KLO07967.1 - 0.00048 19.5 0.1 0.0011 18.4 0.1 1.6 1 0 0 1 1 1 1 SWIM zinc finger PQQ PF01011.16 KLO07968.1 - 0.051 13.1 0.0 0.13 11.8 0.0 1.8 1 0 0 1 1 1 0 PQQ enzyme repeat Pirin PF02678.11 KLO07969.1 - 3.6e-31 107.2 0.2 7.5e-31 106.1 0.2 1.6 1 0 0 1 1 1 1 Pirin Pirin_C PF05726.8 KLO07969.1 - 6.1e-25 87.2 0.1 2.1e-24 85.5 0.0 1.7 2 0 0 2 2 2 1 Pirin C-terminal cupin domain Cupin_2 PF07883.6 KLO07969.1 - 0.0091 15.4 0.4 0.15 11.5 0.3 2.4 2 0 0 2 2 2 1 Cupin domain ECH PF00378.15 KLO07970.1 - 7.1e-30 103.9 0.0 8.7e-30 103.6 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family Pheromone PF08015.6 KLO07972.1 - 0.0024 18.6 0.8 0.0044 17.8 0.1 1.9 2 0 0 2 2 2 1 Fungal mating-type pheromone DP PF08781.5 KLO07972.1 - 0.0049 16.5 0.0 0.0064 16.1 0.0 1.2 1 0 0 1 1 1 1 Transcription factor DP CRM1_C PF08767.6 KLO07973.1 - 3.6e-128 426.9 0.0 3.6e-128 426.9 0.0 3.6 4 0 0 4 4 4 1 CRM1 C terminal Xpo1 PF08389.7 KLO07973.1 - 6.5e-41 139.6 6.1 6.5e-41 139.6 4.2 3.5 4 0 0 4 4 4 1 Exportin 1-like protein IBN_N PF03810.14 KLO07973.1 - 6.2e-11 42.0 0.6 3.1e-10 39.7 0.4 2.4 1 0 0 1 1 1 1 Importin-beta N-terminal domain DUF3385 PF11865.3 KLO07973.1 - 0.013 15.4 0.2 0.13 12.1 0.0 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3385) Vac14_Fab1_bd PF12755.2 KLO07973.1 - 0.51 10.7 4.0 11 6.5 0.0 4.2 4 0 0 4 4 4 0 Vacuolar 14 Fab1-binding region PUA PF01472.15 KLO07974.1 - 1.8e-15 56.3 0.0 2.7e-15 55.8 0.0 1.3 1 0 0 1 1 1 1 PUA domain BHD_1 PF10403.4 KLO07974.1 - 0.11 12.0 0.0 0.27 10.7 0.0 1.6 1 0 0 1 1 1 0 Rad4 beta-hairpin domain 1 OTU PF02338.14 KLO07975.1 - 2.7e-19 69.9 0.0 1.1e-18 68.0 0.0 1.8 2 0 0 2 2 2 1 OTU-like cysteine protease Peptidase_C65 PF10275.4 KLO07975.1 - 2e-08 33.8 0.0 0.00013 21.4 0.0 2.6 3 0 0 3 3 3 2 Peptidase C65 Otubain HAND PF09110.6 KLO07975.1 - 0.76 10.1 7.5 1.1 9.6 5.2 1.2 1 0 0 1 1 1 0 HAND Aldo_ket_red PF00248.16 KLO07976.1 - 8.6e-48 162.5 0.0 9.7e-48 162.4 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Cpn60_TCP1 PF00118.19 KLO07978.1 - 4.7e-139 464.1 8.3 5.3e-139 463.9 5.8 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family COesterase PF00135.23 KLO07979.1 - 5.5e-79 266.2 0.1 1.3e-78 265.0 0.1 1.5 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 KLO07979.1 - 2.2e-08 33.9 0.0 6.2e-08 32.4 0.0 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 KLO07980.1 - 2.1e-17 63.7 0.4 4.3e-17 62.7 0.0 1.7 2 0 0 2 2 2 1 Alpha/beta hydrolase family Esterase PF00756.15 KLO07980.1 - 0.0006 19.3 0.0 0.0012 18.3 0.0 1.4 1 0 0 1 1 1 1 Putative esterase Abhydrolase_1 PF00561.15 KLO07980.1 - 0.0039 16.7 0.1 0.0082 15.7 0.0 1.6 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KLO07980.1 - 0.0065 16.2 0.0 0.02 14.6 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 KLO07980.1 - 0.024 13.8 0.0 0.041 13.0 0.0 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family PAF-AH_p_II PF03403.8 KLO07980.1 - 0.13 10.5 0.0 0.19 9.9 0.0 1.2 1 0 0 1 1 1 0 Platelet-activating factor acetylhydrolase, isoform II SRR1 PF07985.7 KLO07981.1 - 5.6e-10 38.9 1.2 2e-09 37.2 0.4 2.2 2 1 0 2 2 2 1 SRR1 TPR_11 PF13414.1 KLO07983.1 - 8.7e-29 98.9 23.7 2e-07 30.5 0.3 7.7 7 1 1 8 8 8 5 TPR repeat TPR_1 PF00515.23 KLO07983.1 - 8.6e-23 78.9 11.4 1.6e-05 24.2 0.1 8.0 8 0 0 8 8 8 5 Tetratricopeptide repeat TPR_2 PF07719.12 KLO07983.1 - 1.7e-20 71.2 19.0 0.0026 17.5 0.2 9.6 10 0 0 10 10 10 4 Tetratricopeptide repeat Apc3 PF12895.2 KLO07983.1 - 2.8e-16 59.4 27.5 4.2e-13 49.2 2.1 5.5 3 1 4 7 7 7 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.1 KLO07983.1 - 3e-16 59.4 14.4 0.00043 20.5 0.1 7.8 7 1 1 8 8 8 5 Tetratricopeptide repeat TPR_12 PF13424.1 KLO07983.1 - 1.2e-15 57.2 16.7 1.1e-05 25.2 0.1 7.9 6 1 3 9 9 9 5 Tetratricopeptide repeat TPR_16 PF13432.1 KLO07983.1 - 3.1e-15 56.3 29.4 1.4e-06 28.8 0.4 7.7 7 1 1 8 8 8 4 Tetratricopeptide repeat TPR_14 PF13428.1 KLO07983.1 - 5e-12 45.3 18.9 0.16 12.6 0.1 9.5 5 1 5 10 10 10 4 Tetratricopeptide repeat TPR_8 PF13181.1 KLO07983.1 - 3.5e-11 42.0 0.5 4.4 7.3 0.1 8.1 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_17 PF13431.1 KLO07983.1 - 1.4e-09 37.3 9.5 1.4 9.2 0.0 8.3 9 0 0 9 9 9 2 Tetratricopeptide repeat TPR_6 PF13174.1 KLO07983.1 - 6.5e-06 26.2 20.8 1.3 9.6 0.0 9.0 10 0 0 10 10 9 2 Tetratricopeptide repeat TPR_7 PF13176.1 KLO07983.1 - 0.00055 19.5 7.5 1.4 8.9 0.0 7.0 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_9 PF13371.1 KLO07983.1 - 0.0023 17.7 5.0 0.22 11.3 0.3 4.0 3 0 0 3 3 3 1 Tetratricopeptide repeat Viral_cys_rich PF08008.7 KLO07984.1 - 0.13 11.8 0.0 0.16 11.5 0.0 1.1 1 0 0 1 1 1 0 Viral cysteine rich PaREP1 PF05942.6 KLO07987.1 - 0.00016 21.5 0.9 0.00034 20.4 0.0 2.1 2 0 0 2 2 2 1 Archaeal PaREP1/PaREP8 family Orbi_VP5 PF00901.12 KLO07987.1 - 0.00084 17.6 1.9 0.0015 16.8 0.1 2.0 2 0 0 2 2 2 1 Orbivirus outer capsid protein VP5 DUF2383 PF09537.5 KLO07987.1 - 0.00088 19.4 8.2 0.11 12.7 0.3 3.3 3 0 0 3 3 3 2 Domain of unknown function (DUF2383) COQ7 PF03232.8 KLO07987.1 - 0.00091 18.7 5.9 0.065 12.7 0.0 3.7 4 0 0 4 4 4 1 Ubiquinone biosynthesis protein COQ7 DUF465 PF04325.8 KLO07987.1 - 0.0045 16.6 0.3 0.015 15.0 0.0 2.1 2 0 0 2 2 1 1 Protein of unknown function (DUF465) DUF2563 PF10817.3 KLO07987.1 - 0.0051 17.2 0.6 0.012 16.0 0.4 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2563) Herpes_UL6 PF01763.11 KLO07987.1 - 0.062 11.4 6.2 0.047 11.8 0.3 2.4 2 0 0 2 2 2 0 Herpesvirus UL6 like DUF972 PF06156.8 KLO07987.1 - 0.29 11.5 14.9 0.56 10.5 1.0 3.5 4 0 0 4 4 4 0 Protein of unknown function (DUF972) GrpE PF01025.14 KLO07987.1 - 0.35 10.3 12.0 1.5 8.3 0.6 3.0 3 0 0 3 3 3 0 GrpE HALZ PF02183.13 KLO07987.1 - 0.64 9.7 3.6 1.4 8.7 0.2 2.6 2 0 0 2 2 2 0 Homeobox associated leucine zipper DUF904 PF06005.7 KLO07987.1 - 0.64 10.3 16.1 1.1 9.6 2.7 3.6 3 0 0 3 3 3 0 Protein of unknown function (DUF904) RTBV_P46 PF06216.6 KLO07987.1 - 0.71 8.6 4.8 1.2 7.8 0.4 2.2 2 0 0 2 2 2 0 Rice tungro bacilliform virus P46 protein TSC22 PF01166.13 KLO07987.1 - 1 9.3 8.6 2.4 8.1 0.6 3.3 3 0 0 3 3 3 0 TSC-22/dip/bun family Med9 PF07544.8 KLO07987.1 - 1.3 8.8 13.8 1.1 9.1 1.6 3.2 3 0 0 3 3 2 0 RNA polymerase II transcription mediator complex subunit 9 Enkurin PF13864.1 KLO07987.1 - 1.4 9.1 14.9 1.6 8.9 0.2 3.7 4 0 0 4 4 4 0 Calmodulin-binding TMF_DNA_bd PF12329.3 KLO07987.1 - 1.5 8.6 22.0 1.2 9.0 2.7 4.4 4 0 0 4 4 4 0 TATA element modulatory factor 1 DNA binding DUF3450 PF11932.3 KLO07987.1 - 3 7.0 14.7 0.25 10.5 0.3 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF3450) FlaC_arch PF05377.6 KLO07987.1 - 3.2 7.7 8.4 16 5.4 0.5 2.9 2 1 0 2 2 2 0 Flagella accessory protein C (FlaC) Tnp_P_element PF12017.3 KLO07987.1 - 4.5 6.4 6.9 1 8.5 0.7 2.4 2 0 0 2 2 2 0 Transposase protein Atg14 PF10186.4 KLO07987.1 - 5.4 5.8 15.4 1.1 8.1 2.4 2.8 3 0 0 3 3 3 0 UV radiation resistance protein and autophagy-related subunit 14 WD40_alt PF14077.1 KLO07987.1 - 8.7 6.0 6.6 3.8 7.2 2.6 1.8 2 0 0 2 2 1 0 Alternative WD40 repeat motif Mog1 PF04603.7 KLO07989.1 - 2.9e-27 95.3 0.4 4.3e-21 75.3 0.1 2.4 2 1 1 3 3 3 2 Ran-interacting Mog1 protein Ndc80_HEC PF03801.8 KLO07990.1 - 1.7e-31 108.8 0.0 3.9e-31 107.6 0.0 1.5 1 0 0 1 1 1 1 HEC/Ndc80p family IncA PF04156.9 KLO07990.1 - 0.00029 20.4 7.2 0.00029 20.4 5.0 3.0 2 1 0 2 2 2 1 IncA protein AAA_13 PF13166.1 KLO07990.1 - 0.0012 17.4 19.4 0.004 15.6 4.0 2.2 2 0 0 2 2 2 2 AAA domain Fib_alpha PF08702.5 KLO07990.1 - 0.25 11.4 22.9 0.87 9.7 4.5 3.7 2 2 1 3 3 3 0 Fibrinogen alpha/beta chain family TMP_2 PF06791.8 KLO07990.1 - 0.41 10.2 4.7 0.37 10.3 0.0 2.9 4 0 0 4 4 4 0 Prophage tail length tape measure protein Baculo_PEP_C PF04513.7 KLO07990.1 - 1 9.1 12.0 3.7 7.3 1.3 3.7 3 1 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Spc7 PF08317.6 KLO07990.1 - 1.1 7.8 32.8 0.81 8.2 5.7 3.4 2 2 1 3 3 3 0 Spc7 kinetochore protein Filament PF00038.16 KLO07990.1 - 1.2 8.4 31.9 0.43 9.9 14.6 2.9 1 1 2 3 3 3 0 Intermediate filament protein Uds1 PF15456.1 KLO07990.1 - 2.2 8.2 17.9 0.59 10.1 4.9 3.8 1 1 2 3 3 3 0 Up-regulated During Septation APG6 PF04111.7 KLO07990.1 - 4.2 6.3 31.2 0.14 11.1 5.1 3.1 2 1 1 3 3 3 0 Autophagy protein Apg6 DUF724 PF05266.9 KLO07990.1 - 5.2 6.6 20.9 0.1 12.1 2.5 3.1 2 1 0 2 2 2 0 Protein of unknown function (DUF724) PTN_MK_C PF01091.13 KLO07991.1 - 0.41 10.6 2.3 0.66 10.0 0.6 1.9 2 0 0 2 2 2 0 PTN/MK heparin-binding protein family, C-terminal domain F-box-like PF12937.2 KLO07993.1 - 3e-06 26.8 0.5 1.4e-05 24.6 0.4 2.3 1 1 0 1 1 1 1 F-box-like F-box PF00646.28 KLO07993.1 - 0.17 11.5 3.8 8.3 6.1 0.3 3.8 4 0 0 4 4 4 0 F-box domain F-box-like PF12937.2 KLO07994.1 - 1.1e-08 34.6 0.5 3.2e-08 33.1 0.3 1.9 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KLO07994.1 - 0.13 12.0 5.7 2.6 7.8 0.2 3.5 4 0 0 4 4 4 0 F-box domain Surp PF01805.15 KLO07994.1 - 0.27 10.8 3.2 0.72 9.5 0.5 2.2 2 0 0 2 2 2 0 Surp module F-box-like PF12937.2 KLO07995.1 - 3.1e-05 23.6 0.1 3.1e-05 23.6 0.1 2.3 3 0 0 3 3 3 1 F-box-like F-box-like_2 PF13013.1 KLO07995.1 - 0.0028 17.3 0.1 0.01 15.5 0.0 1.9 2 0 0 2 2 2 1 F-box-like domain SelB-wing_1 PF09105.5 KLO07995.1 - 0.14 11.8 1.0 11 5.7 0.0 3.3 3 0 0 3 3 3 0 Elongation factor SelB, winged helix F-box-like PF12937.2 KLO07996.1 - 5.2e-08 32.4 0.1 1.8e-07 30.7 0.0 2.0 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KLO07996.1 - 0.2 11.3 3.6 18 5.1 0.2 3.9 4 0 0 4 4 4 0 F-box domain F-box-like PF12937.2 KLO07998.1 - 3.3e-06 26.7 0.1 8.7e-06 25.3 0.1 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KLO07998.1 - 0.038 13.6 0.2 19 5.0 0.0 3.6 3 0 0 3 3 3 0 F-box domain F-box-like PF12937.2 KLO07999.1 - 2.6e-09 36.6 0.2 6.5e-09 35.3 0.1 1.8 1 0 0 1 1 1 1 F-box-like F-box-like PF12937.2 KLO08000.1 - 0.0002 21.0 0.0 0.00048 19.7 0.0 1.7 1 0 0 1 1 1 1 F-box-like LRR_8 PF13855.1 KLO08000.1 - 0.26 11.0 3.9 0.84 9.4 1.5 2.7 2 1 1 3 3 3 0 Leucine rich repeat F-box-like PF12937.2 KLO08001.1 - 3.7e-07 29.7 1.6 6.8e-07 28.9 0.1 2.3 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 KLO08001.1 - 0.0043 16.6 3.2 17 5.1 0.0 4.4 4 0 0 4 4 4 3 F-box domain Wbp11 PF09429.5 KLO08003.1 - 7.3e-12 45.0 10.9 3.7e-11 42.8 5.7 2.5 2 0 0 2 2 2 1 WW domain binding protein 11 DUF1793 PF08760.6 KLO08004.1 - 3.4e-37 127.9 0.0 6.3e-37 127.0 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1793) Bac_rhamnosid PF05592.6 KLO08004.1 - 0.0064 14.7 0.0 0.018 13.2 0.0 1.6 1 1 0 1 1 1 1 Bacterial alpha-L-rhamnosidase DUF1649 PF07855.7 KLO08005.1 - 2.4e-37 128.1 0.0 2.7e-37 127.9 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1649) PPV_E2_C PF00511.12 KLO08005.1 - 0.11 12.4 0.9 0.28 11.1 0.1 2.0 3 0 0 3 3 3 0 E2 (early) protein, C terminal Sugar_tr PF00083.19 KLO08006.1 - 4.6e-76 256.2 22.3 5.3e-76 256.0 15.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KLO08006.1 - 1.5e-22 79.7 44.2 8.3e-22 77.3 16.5 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Cpn60_TCP1 PF00118.19 KLO08007.1 - 3.6e-154 513.9 2.2 4.1e-154 513.8 1.5 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family F-box-like PF12937.2 KLO08008.1 - 0.00016 21.3 0.1 0.00045 19.8 0.1 1.9 1 0 0 1 1 1 1 F-box-like F-box-like PF12937.2 KLO08010.1 - 0.00054 19.6 0.2 0.0024 17.5 0.1 2.3 1 1 1 2 2 2 1 F-box-like F-box-like PF12937.2 KLO08011.1 - 2.1e-06 27.3 1.3 5e-06 26.1 0.9 1.7 1 0 0 1 1 1 1 F-box-like F-box-like PF12937.2 KLO08012.1 - 2.8e-06 26.9 2.3 5.6e-06 25.9 0.9 2.1 2 0 0 2 2 2 1 F-box-like F-box-like PF12937.2 KLO08013.1 - 0.0023 17.5 0.6 0.0073 16.0 0.0 2.2 2 0 0 2 2 2 1 F-box-like F-box-like PF12937.2 KLO08014.1 - 0.00048 19.7 0.1 0.0018 17.9 0.1 2.0 1 0 0 1 1 1 1 F-box-like Pkinase_Tyr PF07714.12 KLO08015.1 - 1.5e-39 135.6 0.0 2.9e-39 134.6 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 KLO08015.1 - 2.6e-37 128.3 0.0 3.3e-37 128.0 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.1 KLO08015.1 - 8.6e-06 24.9 0.0 1.2e-05 24.4 0.0 1.1 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.17 KLO08015.1 - 7.8e-05 22.0 0.0 0.00011 21.5 0.0 1.2 1 0 0 1 1 1 1 RIO1 family APH PF01636.18 KLO08015.1 - 0.061 13.0 0.0 0.087 12.5 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family Cupin_2 PF07883.6 KLO08016.1 - 7e-08 31.8 0.0 1.3e-07 30.9 0.0 1.5 1 0 0 1 1 1 1 Cupin domain Cupin_6 PF12852.2 KLO08016.1 - 0.0016 18.0 0.0 0.0022 17.6 0.0 1.2 1 0 0 1 1 1 1 Cupin Cupin_3 PF05899.7 KLO08016.1 - 0.0018 17.6 0.0 0.0031 16.8 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF861) DUF3792 PF12670.2 KLO08017.1 - 3 7.7 15.3 0.6 9.9 0.4 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF3792) Pkinase_Tyr PF07714.12 KLO08018.1 - 1.1e-47 162.3 0.0 1.3e-47 162.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 KLO08018.1 - 6e-47 159.9 0.0 7.4e-47 159.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.1 KLO08018.1 - 5.6e-09 35.3 0.0 8.8e-09 34.7 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 KLO08018.1 - 4e-05 23.4 0.0 6.5e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.17 KLO08018.1 - 0.0049 16.2 0.0 0.0077 15.5 0.0 1.3 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.9 KLO08018.1 - 0.03 13.3 0.0 0.041 12.9 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH_6_hur PF04655.9 KLO08018.1 - 0.071 12.2 0.0 0.13 11.3 0.0 1.4 1 1 0 1 1 1 0 Aminoglycoside/hydroxyurea antibiotic resistance kinase Cupin_2 PF07883.6 KLO08019.1 - 4.6e-11 42.0 0.0 7.4e-11 41.4 0.0 1.3 1 0 0 1 1 1 1 Cupin domain Cupin_6 PF12852.2 KLO08019.1 - 0.0018 17.8 0.0 0.0025 17.4 0.0 1.2 1 0 0 1 1 1 1 Cupin AraC_binding PF02311.14 KLO08019.1 - 0.048 13.3 0.0 0.076 12.6 0.0 1.3 1 0 0 1 1 1 0 AraC-like ligand binding domain DAP3 PF10236.4 KLO08019.1 - 0.11 11.3 0.0 0.15 10.9 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 PMI_typeI PF01238.16 KLO08020.1 - 3.1e-80 269.9 0.0 4.2e-80 269.5 0.0 1.1 1 0 0 1 1 1 1 Phosphomannose isomerase type I DUF3457 PF11939.3 KLO08020.1 - 0.088 12.3 0.0 0.19 11.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3457) zf-RING_2 PF13639.1 KLO08021.1 - 2.4e-10 40.0 10.3 2.4e-10 40.0 7.1 3.9 3 2 1 4 4 3 1 Ring finger domain zf-C3HC4_3 PF13920.1 KLO08021.1 - 3.9e-08 32.8 8.2 3.9e-08 32.8 5.7 4.4 3 2 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KLO08021.1 - 9.1e-08 31.7 9.4 9.1e-08 31.7 6.5 4.4 4 1 1 5 5 5 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 KLO08021.1 - 2e-07 30.8 10.5 2e-07 30.8 7.3 4.3 4 1 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KLO08021.1 - 5.1e-06 26.0 9.8 5.1e-06 26.0 6.8 3.4 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 KLO08021.1 - 0.0009 19.3 5.4 0.0009 19.3 3.7 3.7 3 2 0 3 3 3 1 RING-H2 zinc finger zf-RING_UBOX PF13445.1 KLO08021.1 - 0.0019 17.8 8.9 0.0027 17.4 2.6 3.2 2 1 1 3 3 3 1 RING-type zinc-finger zf-RING_6 PF14835.1 KLO08021.1 - 0.0037 17.0 0.5 0.0037 17.0 0.3 2.5 3 0 0 3 3 2 1 zf-RING of BARD1-type protein zf-C2H2 PF00096.21 KLO08021.1 - 0.021 15.1 37.7 0.1 13.0 1.9 6.0 6 0 0 6 6 6 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KLO08021.1 - 0.033 14.5 0.5 0.033 14.5 0.3 6.2 5 1 0 5 5 4 0 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 KLO08021.1 - 0.034 14.2 1.2 0.034 14.2 0.8 5.8 7 0 0 7 7 7 0 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 KLO08021.1 - 0.053 13.7 0.3 0.053 13.7 0.2 6.5 7 1 0 7 7 6 0 Zinc-finger of C2H2 type zf-H2C2_2 PF13465.1 KLO08021.1 - 0.69 10.3 24.6 7.6 7.0 0.0 6.3 6 0 0 6 6 6 0 Zinc-finger double domain zf-C3HC4_3 PF13920.1 KLO08022.1 - 4.8e-09 35.7 5.7 4.8e-09 35.7 3.9 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KLO08022.1 - 2.1e-06 27.4 8.0 2.1e-06 27.4 5.6 3.6 4 1 1 5 5 5 1 Ring finger domain zf-C3HC4_2 PF13923.1 KLO08022.1 - 2.4e-06 27.4 6.5 2.4e-06 27.4 4.5 2.8 4 0 0 4 4 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KLO08022.1 - 4.6e-06 26.1 4.3 4.6e-06 26.1 3.0 2.3 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KLO08022.1 - 4.8e-06 26.1 7.9 4.8e-06 26.1 5.5 3.5 4 1 1 5 5 4 1 zinc-RING finger domain Prok-RING_4 PF14447.1 KLO08022.1 - 0.00011 21.6 7.5 0.00053 19.4 5.2 2.0 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_4 PF14570.1 KLO08022.1 - 0.0012 18.4 10.0 0.12 11.9 7.1 2.6 1 1 1 2 2 2 1 RING/Ubox like zinc-binding domain zf-RING_UBOX PF13445.1 KLO08022.1 - 0.0034 17.0 2.4 0.0034 17.0 1.7 2.4 2 1 0 2 2 2 1 RING-type zinc-finger TerY-C PF15616.1 KLO08022.1 - 0.0052 16.7 2.1 0.0052 16.7 1.5 1.5 2 0 0 2 2 1 1 TerY-C metal binding domain zf-H2C2_2 PF13465.1 KLO08022.1 - 0.012 15.8 6.8 0.74 10.2 0.1 4.2 4 0 0 4 4 4 0 Zinc-finger double domain Baculo_IE-1 PF05290.6 KLO08022.1 - 0.045 13.4 1.3 0.081 12.6 0.3 1.8 2 0 0 2 2 2 0 Baculovirus immediate-early protein (IE-0) zf-C2H2 PF00096.21 KLO08022.1 - 0.43 11.0 0.1 0.43 11.0 0.1 4.9 5 0 0 5 5 5 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KLO08022.1 - 0.81 10.1 18.1 3.5 8.1 0.1 5.2 6 0 0 6 6 5 0 C2H2-type zinc finger zf-RING_6 PF14835.1 KLO08022.1 - 0.95 9.2 14.6 0.8 9.5 3.7 3.9 3 2 1 4 4 4 0 zf-RING of BARD1-type protein zf-C2H2_6 PF13912.1 KLO08022.1 - 1.4 8.8 13.4 6.8 6.7 0.4 4.2 4 0 0 4 4 4 0 C2H2-type zinc finger zf-rbx1 PF12678.2 KLO08022.1 - 4.3 7.5 11.7 0.3 11.2 2.6 3.0 3 1 0 3 3 3 0 RING-H2 zinc finger zf-P11 PF03854.9 KLO08022.1 - 5.2 6.6 10.1 0.86 9.1 2.6 2.8 2 1 0 2 2 2 0 P-11 zinc finger zf-C3HC4_3 PF13920.1 KLO08023.1 - 5.5e-11 41.9 9.0 5.5e-11 41.9 6.2 4.0 4 1 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KLO08023.1 - 3.1e-09 36.5 10.2 3.1e-09 36.5 7.1 3.5 3 2 0 3 3 2 1 Ring finger domain zf-C3HC4_2 PF13923.1 KLO08023.1 - 5.9e-08 32.5 10.3 5.9e-08 32.5 7.1 4.1 4 1 0 4 4 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KLO08023.1 - 7.5e-08 31.8 9.5 7.5e-08 31.8 6.6 3.3 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KLO08023.1 - 2.8e-07 30.1 8.6 2.8e-07 30.1 5.9 4.4 3 2 1 4 4 4 1 zinc-RING finger domain zf-C2H2 PF00096.21 KLO08023.1 - 3.7e-06 26.9 0.7 0.0022 18.2 0.0 5.9 6 0 0 6 6 5 3 Zinc finger, C2H2 type zf-C3HC4_4 PF15227.1 KLO08023.1 - 1.3e-05 24.9 6.5 1.3e-05 24.9 4.5 3.8 5 1 0 5 5 4 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 KLO08023.1 - 3.9e-05 23.2 8.6 0.0017 18.0 3.3 3.2 2 1 1 3 3 3 1 RING-type zinc-finger zf-rbx1 PF12678.2 KLO08023.1 - 0.00023 21.1 2.4 0.00023 21.1 1.7 2.8 3 0 0 3 3 3 1 RING-H2 zinc finger Rtf2 PF04641.7 KLO08023.1 - 0.0014 17.8 0.8 0.014 14.5 0.1 2.1 2 0 0 2 2 2 1 Rtf2 RING-finger zf-RING_4 PF14570.1 KLO08023.1 - 0.0022 17.5 7.0 0.0022 17.5 4.8 4.1 5 1 0 5 5 5 1 RING/Ubox like zinc-binding domain zf-RING_6 PF14835.1 KLO08023.1 - 0.0093 15.7 3.2 0.0093 15.7 2.2 3.4 3 1 0 3 3 3 1 zf-RING of BARD1-type protein zf-met PF12874.2 KLO08023.1 - 0.081 13.1 1.4 0.081 13.1 1.0 6.2 8 1 1 9 9 9 0 Zinc-finger of C2H2 type zf-P11 PF03854.9 KLO08023.1 - 0.11 12.0 10.8 0.042 13.3 1.9 3.4 3 0 0 3 3 3 0 P-11 zinc finger zf-C2H2_4 PF13894.1 KLO08023.1 - 0.14 12.5 0.2 0.14 12.5 0.1 5.9 5 1 0 5 5 4 0 C2H2-type zinc finger zf-C3HC4_3 PF13920.1 KLO08024.1 - 3.8e-07 29.6 4.1 3.8e-07 29.6 2.8 2.6 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KLO08024.1 - 2.6e-05 23.7 5.4 2.6e-05 23.7 3.7 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KLO08024.1 - 0.00041 20.3 5.4 0.00041 20.3 3.7 2.5 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KLO08024.1 - 0.0014 18.3 5.3 0.0014 18.3 3.7 2.5 3 0 0 3 3 3 1 zinc-RING finger domain zf-RING_2 PF13639.1 KLO08024.1 - 0.0046 16.7 6.7 0.0046 16.7 4.6 2.5 3 0 0 3 3 3 1 Ring finger domain zf-C2H2_4 PF13894.1 KLO08024.1 - 0.025 14.8 13.4 1 9.8 0.1 4.1 5 0 0 5 5 3 0 C2H2-type zinc finger zf-LYAR PF08790.6 KLO08024.1 - 0.039 13.6 1.3 1.1 8.9 0.1 2.5 2 0 0 2 2 2 0 LYAR-type C2HC zinc finger Neil1-DNA_bind PF09292.5 KLO08024.1 - 0.11 12.2 0.4 0.25 11.1 0.0 1.7 2 0 0 2 2 2 0 Endonuclease VIII-like 1, DNA bind zf-C2H2 PF00096.21 KLO08024.1 - 0.13 12.6 0.0 0.13 12.6 0.0 4.2 5 0 0 5 5 5 0 Zinc finger, C2H2 type Prok-RING_4 PF14447.1 KLO08024.1 - 0.15 11.6 6.1 0.51 9.9 4.2 2.0 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 zf-C2H2_6 PF13912.1 KLO08024.1 - 0.44 10.5 13.5 0.91 9.5 0.0 4.2 5 0 0 5 5 5 0 C2H2-type zinc finger zf-P11 PF03854.9 KLO08024.1 - 0.53 9.8 8.2 0.071 12.5 1.0 2.6 3 0 0 3 3 3 0 P-11 zinc finger zf-RING_UBOX PF13445.1 KLO08024.1 - 1 9.1 4.1 1.2 8.8 0.8 2.3 1 1 1 2 2 2 0 RING-type zinc-finger zf-C3HC4_4 PF15227.1 KLO08024.1 - 2 8.3 11.6 9.6 6.1 6.0 3.3 2 1 2 4 4 4 0 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.1 KLO08024.1 - 3.8 7.1 12.7 0.069 12.7 3.5 2.1 3 1 0 3 3 3 0 RING/Ubox like zinc-binding domain zf-C3HC4 PF00097.20 KLO08025.1 - 0.0065 16.0 13.0 0.01 15.4 9.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KLO08025.1 - 0.015 14.9 10.7 0.024 14.2 7.4 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KLO08025.1 - 0.034 14.1 14.1 0.055 13.5 9.8 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KLO08025.1 - 0.096 12.4 13.3 0.15 11.8 9.2 1.3 1 0 0 1 1 1 0 zinc-RING finger domain zf-RING_2 PF13639.1 KLO08025.1 - 0.19 11.5 13.4 0.35 10.7 9.3 1.4 1 1 0 1 1 1 0 Ring finger domain zf-RING_6 PF14835.1 KLO08025.1 - 1.9 8.3 7.4 3.7 7.4 5.1 1.4 1 1 0 1 1 1 0 zf-RING of BARD1-type protein Form_Nir_trans PF01226.12 KLO08026.1 - 4e-59 199.5 18.7 5.1e-59 199.1 12.9 1.0 1 0 0 1 1 1 1 Formate/nitrite transporter Methyltransf_10 PF05971.7 KLO08027.1 - 2.7e-73 246.7 0.0 3.4e-73 246.3 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF890) Methyltransf_26 PF13659.1 KLO08027.1 - 0.0011 19.0 0.0 0.0019 18.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 KLO08027.1 - 0.0016 17.6 0.0 0.0024 17.0 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_18 PF12847.2 KLO08027.1 - 0.016 15.7 0.0 0.028 15.0 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_4 PF02390.12 KLO08027.1 - 0.041 12.9 0.0 0.073 12.1 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase Pkinase PF00069.20 KLO08028.1 - 5.8e-06 25.6 0.0 7.8e-06 25.2 0.0 1.3 1 1 0 1 1 1 1 Protein kinase domain APH PF01636.18 KLO08028.1 - 0.037 13.7 0.8 0.046 13.4 0.6 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family DUF4502 PF14950.1 KLO08030.1 - 1.3e-05 24.5 0.0 2.2e-05 23.8 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4502) GTP_EFTU PF00009.22 KLO08031.1 - 7.9e-36 123.2 0.1 1.3e-35 122.5 0.1 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain eIF2_C PF09173.6 KLO08031.1 - 7.7e-32 109.2 0.2 1.8e-31 108.0 0.1 1.6 1 0 0 1 1 1 1 Initiation factor eIF2 gamma, C terminal GTP_EFTU_D2 PF03144.20 KLO08031.1 - 2.9e-09 36.8 0.6 8.7e-09 35.3 0.1 2.0 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 KLO08031.1 - 0.0018 18.2 0.0 0.0038 17.1 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase F-box-like PF12937.2 KLO08032.1 - 0.00032 20.3 0.0 0.0011 18.6 0.0 2.1 1 0 0 1 1 1 1 F-box-like F-box-like PF12937.2 KLO08034.1 - 0.0007 19.2 0.2 0.0029 17.2 0.0 2.3 2 0 0 2 2 2 1 F-box-like LRR_4 PF12799.2 KLO08034.1 - 0.06 12.9 0.5 0.43 10.2 0.0 2.6 2 1 0 2 2 2 0 Leucine Rich repeats (2 copies) F-box-like PF12937.2 KLO08035.1 - 8.6e-07 28.5 2.0 2.3e-06 27.1 1.4 1.8 1 1 0 1 1 1 1 F-box-like F-box PF00646.28 KLO08035.1 - 0.037 13.6 1.0 2.7 7.7 0.1 2.6 2 0 0 2 2 2 0 F-box domain Enhancin PF03272.8 KLO08036.1 - 0.078 10.8 0.1 0.12 10.3 0.1 1.2 1 0 0 1 1 1 0 Viral enhancin protein YojJ PF10372.4 KLO08036.1 - 0.13 12.1 1.5 0.16 11.8 0.4 1.6 1 1 1 2 2 2 0 Bacterial membrane-spanning protein N-terminus DUF4456 PF14644.1 KLO08036.1 - 0.13 11.4 8.9 0.49 9.5 1.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4456) DXP_synthase_N PF13292.1 KLO08036.1 - 0.16 10.8 1.2 0.22 10.4 0.4 1.5 1 1 0 1 1 1 0 1-deoxy-D-xylulose-5-phosphate synthase Enamelin PF15362.1 KLO08036.1 - 0.21 9.6 2.3 0.22 9.5 1.6 1.1 1 0 0 1 1 1 0 Enamelin COG2 PF06148.6 KLO08036.1 - 0.24 11.2 2.6 0.22 11.3 1.3 1.4 1 1 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 AAA_23 PF13476.1 KLO08036.1 - 0.28 11.4 7.7 0.33 11.2 5.3 1.1 1 0 0 1 1 1 0 AAA domain Rgp1 PF08737.5 KLO08036.1 - 0.45 9.5 3.5 0.54 9.2 2.4 1.1 1 0 0 1 1 1 0 Rgp1 DUF1221 PF06760.6 KLO08036.1 - 0.52 9.5 6.0 5.7 6.1 0.2 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1221) NIPSNAP PF07978.8 KLO08037.1 - 0.052 13.5 0.0 0.094 12.7 0.0 1.4 1 0 0 1 1 1 0 NIPSNAP DUF4231 PF14015.1 KLO08037.1 - 3.1 7.8 9.7 9.3 6.2 4.6 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF4231) Lipase_3 PF01764.20 KLO08038.1 - 1e-33 115.9 0.0 1.6e-33 115.2 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) Cutinase PF01083.17 KLO08038.1 - 0.0014 18.4 0.1 0.0039 16.9 0.0 1.8 2 0 0 2 2 2 1 Cutinase HTH_12 PF08461.5 KLO08040.1 - 0.04 13.6 0.0 0.08 12.6 0.0 1.5 1 0 0 1 1 1 0 Ribonuclease R winged-helix domain OPT PF03169.10 KLO08043.1 - 4.4e-180 600.1 55.6 1.3e-179 598.6 38.5 1.6 1 1 0 1 1 1 1 OPT oligopeptide transporter protein PKD_channel PF08016.7 KLO08044.1 - 0.34 9.2 4.4 0.12 10.7 0.6 1.7 1 1 0 2 2 2 0 Polycystin cation channel ABC2_membrane_2 PF12679.2 KLO08044.1 - 0.77 8.5 5.6 0.94 8.2 3.9 1.1 1 0 0 1 1 1 0 ABC-2 family transporter protein DUF3671 PF12420.3 KLO08044.1 - 3.5 7.6 4.8 6.7 6.7 3.4 1.4 1 0 0 1 1 1 0 Protein of unknown function FtsX PF02687.16 KLO08045.1 - 0.034 13.9 8.9 0.033 13.9 3.8 2.0 2 0 0 2 2 2 0 FtsX-like permease family Tmemb_170 PF10190.4 KLO08045.1 - 2.1 8.4 5.9 0.13 12.2 0.7 1.4 2 0 0 2 2 2 0 Putative transmembrane protein 170 SAICAR_synt PF01259.13 KLO08046.1 - 3.7e-78 262.0 0.0 4.9e-62 209.2 0.0 2.0 2 0 0 2 2 2 2 SAICAR synthetase Fis1_TPR_C PF14853.1 KLO08047.1 - 7.6e-18 64.1 0.4 1.3e-17 63.3 0.3 1.4 1 0 0 1 1 1 1 Fis1 C-terminal tetratricopeptide repeat Fis1_TPR_N PF14852.1 KLO08047.1 - 2.6e-15 55.4 0.0 4.7e-15 54.6 0.0 1.4 1 0 0 1 1 1 1 Fis1 N-terminal tetratricopeptide repeat Apc3 PF12895.2 KLO08047.1 - 1.8e-07 31.2 0.1 0.00062 19.8 0.0 1.6 1 1 1 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_2 PF07719.12 KLO08047.1 - 2.1e-05 24.0 0.1 0.00011 21.8 0.0 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.1 KLO08047.1 - 0.0016 18.7 0.1 0.0041 17.4 0.1 1.7 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_14 PF13428.1 KLO08047.1 - 0.0068 16.9 0.1 0.43 11.3 0.0 3.0 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.1 KLO08047.1 - 0.011 16.4 0.0 0.48 11.1 0.0 2.5 3 1 2 5 5 3 0 Tetratricopeptide repeat TPR_1 PF00515.23 KLO08047.1 - 0.012 15.2 0.4 0.039 13.5 0.0 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.1 KLO08047.1 - 0.025 14.9 0.1 0.24 11.9 0.0 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.1 KLO08047.1 - 0.059 13.3 0.1 0.23 11.4 0.0 2.0 1 1 1 2 2 2 0 Tetratricopeptide repeat Gram_pos_anchor PF00746.16 KLO08047.1 - 0.71 9.7 2.6 1.3 8.9 1.8 1.4 1 0 0 1 1 1 0 Gram positive anchor zf-H2C2_2 PF13465.1 KLO08048.1 - 6e-26 89.4 36.1 1.4e-07 31.4 0.9 7.0 7 0 0 7 7 7 4 Zinc-finger double domain zf-C2H2 PF00096.21 KLO08048.1 - 2.7e-21 74.5 51.0 3.5e-05 23.8 1.2 8.4 9 0 0 9 9 9 6 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KLO08048.1 - 2.9e-12 45.9 47.0 0.00024 21.1 0.9 8.1 8 0 0 8 8 8 5 C2H2-type zinc finger zf-C2H2_6 PF13912.1 KLO08048.1 - 5.8e-06 26.0 17.5 0.032 14.1 0.7 5.6 5 0 0 5 5 5 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 KLO08048.1 - 2.5e-05 24.2 16.3 0.12 12.5 0.3 5.9 5 0 0 5 5 5 2 Zinc-finger double-stranded RNA-binding zf-H2C2_5 PF13909.1 KLO08048.1 - 0.023 14.9 2.4 0.023 14.9 1.6 6.1 6 0 0 6 6 6 0 C2H2-type zinc-finger domain Zn_Tnp_IS1 PF03811.8 KLO08048.1 - 0.023 14.1 7.3 0.046 13.2 0.5 3.2 2 0 0 2 2 2 0 InsA N-terminal domain zf-C2H2_2 PF12756.2 KLO08048.1 - 1 9.5 23.6 0.074 13.1 3.8 4.4 3 2 2 5 5 5 0 C2H2 type zinc-finger (2 copies) zf-C2HC_2 PF13913.1 KLO08048.1 - 1.2 8.8 15.5 13 5.5 0.0 5.8 6 0 0 6 6 6 0 zinc-finger of a C2HC-type zf-met PF12874.2 KLO08048.1 - 2.9 8.2 20.3 0.18 12.0 0.6 5.1 5 0 0 5 5 5 0 Zinc-finger of C2H2 type DUF2962 PF11176.3 KLO08049.1 - 3.9e-37 127.2 3.0 4.5e-37 127.0 2.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2962) Pkinase PF00069.20 KLO08050.1 - 1.6e-71 240.4 0.0 3.4e-71 239.4 0.0 1.5 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 KLO08050.1 - 1.9e-33 115.6 0.0 3.1e-33 114.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KLO08050.1 - 0.00069 18.6 0.0 0.0048 15.9 0.0 2.0 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 KLO08050.1 - 0.0017 18.1 0.0 0.022 14.4 0.0 2.2 1 1 1 2 2 2 1 Phosphotransferase enzyme family DNA_ligase_A_M PF01068.16 KLO08051.1 - 1.6e-52 177.8 0.1 3.1e-52 176.8 0.0 1.5 1 0 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.9 KLO08051.1 - 9.1e-43 146.1 0.0 2.2e-42 144.8 0.0 1.7 1 0 0 1 1 1 1 DNA ligase N terminus DNA_ligase_A_C PF04679.10 KLO08051.1 - 1.4e-11 44.6 0.0 7e-11 42.3 0.0 2.3 2 0 0 2 2 2 1 ATP dependent DNA ligase C terminal region BRCT PF00533.21 KLO08051.1 - 2.3e-11 43.6 0.3 1.4e-05 25.1 0.0 3.0 2 1 0 2 2 2 2 BRCA1 C Terminus (BRCT) domain Adaptin_N PF01602.15 KLO08052.1 - 2.8e-145 484.6 8.1 3.2e-145 484.4 5.6 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptinC2 PF02883.15 KLO08052.1 - 2.3e-22 79.4 0.9 4.6e-22 78.5 0.6 1.5 1 0 0 1 1 1 1 Adaptin C-terminal domain HEAT_2 PF13646.1 KLO08052.1 - 2.9e-06 27.4 5.9 0.24 11.6 0.0 4.8 4 2 0 4 4 4 3 HEAT repeats HEAT PF02985.17 KLO08052.1 - 0.0002 21.1 2.0 21 5.5 0.0 5.7 5 0 0 5 5 5 0 HEAT repeat Cnd1 PF12717.2 KLO08052.1 - 0.0041 16.9 3.6 0.04 13.7 0.7 3.2 2 2 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 TIP120 PF08623.5 KLO08052.1 - 0.0052 16.3 2.5 0.023 14.2 0.1 2.9 2 1 1 3 3 3 1 TATA-binding protein interacting (TIP20) RIX1 PF08167.7 KLO08052.1 - 0.016 14.9 1.6 0.25 10.9 0.0 3.3 4 2 0 4 4 4 0 rRNA processing/ribosome biogenesis Rz1 PF06085.6 KLO08052.1 - 1.3 8.4 9.3 21 4.6 5.1 2.7 2 0 0 2 2 2 0 Lipoprotein Rz1 precursor AIP3 PF03915.8 KLO08053.1 - 3.3e-106 355.7 8.2 6.4e-106 354.8 5.7 1.5 1 0 0 1 1 1 1 Actin interacting protein 3 FlaC_arch PF05377.6 KLO08053.1 - 0.28 11.1 5.9 8.6 6.3 0.2 3.8 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) Syntaxin_2 PF14523.1 KLO08053.1 - 0.3 11.1 9.1 4.6 7.3 0.0 4.9 4 1 0 4 4 4 0 Syntaxin-like protein RE_MjaI PF09568.5 KLO08053.1 - 1.5 8.3 4.5 2.4 7.6 0.1 3.1 4 0 0 4 4 4 0 MjaI restriction endonuclease Lectin_N PF03954.9 KLO08053.1 - 3.5 7.0 6.9 0.4 10.0 0.6 2.7 3 0 0 3 3 3 0 Hepatic lectin, N-terminal domain Baculo_PEP_C PF04513.7 KLO08053.1 - 4.1 7.2 12.3 19 5.0 0.7 4.7 4 2 0 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF1664 PF07889.7 KLO08053.1 - 4.4 7.1 7.6 15 5.3 1.7 3.7 1 1 1 3 3 3 0 Protein of unknown function (DUF1664) PALP PF00291.20 KLO08054.1 - 9.1e-54 182.7 0.2 1.1e-53 182.5 0.1 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme NaeI PF09126.5 KLO08054.1 - 0.026 13.1 0.0 0.041 12.5 0.0 1.2 1 0 0 1 1 1 0 Restriction endonuclease NaeI Sugar_tr PF00083.19 KLO08055.1 - 7.1e-74 248.9 23.3 8.1e-74 248.8 16.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KLO08055.1 - 2.8e-23 82.2 33.2 2.8e-23 82.2 23.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Pam17 PF08566.5 KLO08055.1 - 0.068 12.8 0.0 0.23 11.1 0.0 1.8 2 0 0 2 2 2 0 Mitochondrial import protein Pam17 DOPA_dioxygen PF08883.6 KLO08056.1 - 2.4e-31 107.8 0.1 3e-31 107.5 0.0 1.1 1 0 0 1 1 1 1 Dopa 4,5-dioxygenase family E1_DerP2_DerF2 PF02221.10 KLO08057.1 - 1.4e-23 83.5 0.5 1.8e-23 83.2 0.3 1.1 1 0 0 1 1 1 1 ML domain TRP_N PF14558.1 KLO08057.1 - 0.0012 18.8 0.1 0.0023 17.9 0.1 1.5 1 1 0 1 1 1 1 ML-like domain Zfx_Zfy_act PF04704.8 KLO08059.1 - 0.0037 16.1 3.3 0.0037 16.1 2.3 1.0 1 0 0 1 1 1 1 Zfx / Zfy transcription activation region FLgD_tudor PF13861.1 KLO08059.1 - 0.35 10.9 4.4 1.7 8.7 3.1 1.9 1 1 0 1 1 1 0 FlgD Tudor-like domain Red1 PF07964.6 KLO08059.1 - 0.95 7.5 4.7 1.2 7.2 3.3 1.0 1 0 0 1 1 1 0 Rec10 / Red1 Sds3 PF08598.6 KLO08060.1 - 1.1e-09 38.1 0.0 1.6e-09 37.6 0.0 1.3 1 0 0 1 1 1 1 Sds3-like Fork_head PF00250.13 KLO08061.1 - 1.7e-13 50.4 0.1 2.1e-13 50.1 0.1 1.1 1 0 0 1 1 1 1 Fork head domain SF3b1 PF08920.5 KLO08062.1 - 2.3e-23 82.8 6.3 2.3e-23 82.8 4.4 3.4 1 1 1 2 2 2 1 Splicing factor 3B subunit 1 HEAT_2 PF13646.1 KLO08062.1 - 3.1e-13 49.8 11.0 1.5e-05 25.2 0.0 7.4 6 3 1 8 8 8 3 HEAT repeats HEAT PF02985.17 KLO08062.1 - 6.5e-11 41.3 9.1 0.096 12.8 0.0 10.3 12 0 0 12 12 12 2 HEAT repeat HEAT_EZ PF13513.1 KLO08062.1 - 3.3e-09 36.9 7.4 0.0057 17.1 0.0 8.7 7 2 2 9 9 9 2 HEAT-like repeat Adaptin_N PF01602.15 KLO08062.1 - 8.5e-07 27.6 1.5 0.0089 14.3 0.0 3.3 2 1 1 3 3 3 3 Adaptin N terminal region Vac14_Fab1_bd PF12755.2 KLO08062.1 - 1.7e-05 25.1 4.1 0.72 10.2 0.0 5.3 5 0 0 5 5 5 2 Vacuolar 14 Fab1-binding region CLASP_N PF12348.3 KLO08062.1 - 0.0061 15.9 0.9 1.2 8.4 0.0 3.2 2 1 1 3 3 3 1 CLASP N terminal MMS19_C PF12460.3 KLO08062.1 - 0.0091 14.7 0.0 11 4.6 0.0 3.9 2 2 1 3 3 3 1 RNAPII transcription regulator C-terminal NUC173 PF08161.7 KLO08062.1 - 0.023 14.0 0.1 10 5.4 0.0 3.8 4 0 0 4 4 4 0 NUC173 domain Arm PF00514.18 KLO08062.1 - 0.06 13.1 2.6 23 4.9 0.0 4.5 6 0 0 6 6 6 0 Armadillo/beta-catenin-like repeat F-box-like PF12937.2 KLO08063.1 - 1.1e-06 28.2 0.1 3.6e-06 26.5 0.1 1.9 1 0 0 1 1 1 1 F-box-like F-box-like PF12937.2 KLO08065.1 - 1.4e-05 24.7 0.1 4.4e-05 23.1 0.1 2.0 1 0 0 1 1 1 1 F-box-like TRAP_alpha PF03896.11 KLO08065.1 - 4.5 6.1 10.9 6.3 5.7 7.5 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit CobT PF06213.7 KLO08065.1 - 6 5.9 18.4 9.4 5.2 12.8 1.3 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT WD40 PF00400.27 KLO08066.1 - 8.3e-49 161.8 21.4 3.1e-10 39.5 0.1 7.3 6 1 1 7 7 7 7 WD domain, G-beta repeat eIF2A PF08662.6 KLO08066.1 - 3.5e-05 23.5 0.2 0.017 14.8 0.0 2.5 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A Nucleoporin_N PF08801.6 KLO08066.1 - 6.5e-05 21.8 0.0 0.024 13.3 0.0 2.8 2 1 0 2 2 2 2 Nup133 N terminal like Coatomer_WDAD PF04053.9 KLO08066.1 - 0.011 14.5 0.0 0.017 13.9 0.0 1.1 1 0 0 1 1 1 0 Coatomer WD associated region TFIIIC_delta PF12657.2 KLO08066.1 - 0.16 11.7 0.8 3.9 7.1 0.1 2.7 2 2 0 2 2 2 0 Transcription factor IIIC subunit delta N-term IKI3 PF04762.7 KLO08066.1 - 0.21 9.3 0.0 0.42 8.3 0.0 1.4 1 0 0 1 1 1 0 IKI3 family Ribonuc_P_40 PF08584.6 KLO08067.1 - 0.0092 15.0 0.1 0.034 13.1 0.0 1.8 1 1 1 2 2 2 1 Ribonuclease P 40kDa (Rpp40) subunit DUF2408 PF10303.4 KLO08067.1 - 0.032 14.3 0.1 0.23 11.5 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2408) FUSC PF04632.7 KLO08067.1 - 0.036 12.5 0.1 0.05 12.0 0.0 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF2682 PF10909.3 KLO08067.1 - 0.08 13.2 0.0 0.28 11.5 0.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF2682) Methyltransf_31 PF13847.1 KLO08068.1 - 8.8e-18 64.3 0.0 1.2e-17 63.9 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KLO08068.1 - 3.6e-17 62.5 0.0 5e-17 62.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KLO08068.1 - 9.1e-16 58.1 0.0 1.4e-15 57.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KLO08068.1 - 1.1e-14 54.6 0.0 2.1e-14 53.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KLO08068.1 - 5e-14 52.8 0.0 9.2e-14 51.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KLO08068.1 - 4.6e-11 42.9 0.0 9e-11 42.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KLO08068.1 - 2.4e-08 33.9 0.0 4e-08 33.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KLO08068.1 - 2.9e-06 26.7 0.0 4.2e-06 26.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Ubie_methyltran PF01209.13 KLO08068.1 - 1.7e-05 24.0 0.0 3.5e-05 23.0 0.0 1.5 1 1 0 2 2 2 1 ubiE/COQ5 methyltransferase family DREV PF05219.7 KLO08068.1 - 9.6e-05 21.3 0.0 0.00028 19.8 0.0 1.6 1 1 0 1 1 1 1 DREV methyltransferase NodS PF05401.6 KLO08068.1 - 0.0021 17.5 0.0 0.0032 16.8 0.0 1.3 1 0 0 1 1 1 1 Nodulation protein S (NodS) CMAS PF02353.15 KLO08068.1 - 0.017 14.2 0.0 0.02 13.9 0.0 1.1 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase RrnaAD PF00398.15 KLO08068.1 - 0.054 12.5 0.0 0.093 11.7 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase IBR PF01485.16 KLO08069.1 - 3.8e-09 36.2 36.8 8.9e-09 35.0 7.8 4.5 3 2 0 3 3 3 2 IBR domain zf-C3HC4 PF00097.20 KLO08069.1 - 0.0001 21.8 4.4 0.0001 21.8 3.0 4.4 3 1 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KLO08069.1 - 0.00015 21.7 3.2 0.00015 21.7 2.2 4.8 3 2 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KLO08069.1 - 0.0002 21.0 1.9 0.0002 21.0 1.3 3.5 3 1 0 3 3 3 1 zinc-RING finger domain zf-RING_2 PF13639.1 KLO08069.1 - 0.00056 19.6 5.0 0.00056 19.6 3.5 3.4 3 1 1 4 4 4 1 Ring finger domain Flagellin_N PF00669.15 KLO08069.1 - 0.17 11.6 0.8 0.28 10.9 0.5 1.3 1 0 0 1 1 1 0 Bacterial flagellin N-terminal helical region zf-rbx1 PF12678.2 KLO08069.1 - 9.6 6.3 21.5 0.58 10.3 1.4 3.0 2 1 1 3 3 3 0 RING-H2 zinc finger RRM_1 PF00076.17 KLO08070.1 - 9.6e-34 114.8 0.0 8.4e-18 63.7 0.1 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KLO08070.1 - 6.6e-19 67.6 0.0 3.4e-10 39.7 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KLO08070.1 - 1.1e-10 41.2 0.1 0.00046 19.9 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) OB_RNB PF08206.6 KLO08070.1 - 0.049 13.1 0.2 0.59 9.6 0.0 2.2 2 0 0 2 2 2 0 Ribonuclease B OB domain Limkain-b1 PF11608.3 KLO08070.1 - 0.092 12.5 0.0 0.98 9.2 0.0 2.0 2 0 0 2 2 2 0 Limkain b1 COX17 PF05051.8 KLO08071.1 - 1.1e-20 73.3 2.8 1.4e-20 73.0 1.9 1.1 1 0 0 1 1 1 1 Cytochrome C oxidase copper chaperone (COX17) Ofd1_CTDD PF10637.4 KLO08072.1 - 0.13 11.3 0.0 0.15 11.1 0.0 1.0 1 0 0 1 1 1 0 Oxoglutarate and iron-dependent oxygenase degradation C-term PIG-P PF08510.7 KLO08073.1 - 0.76 9.4 4.6 2.2 7.9 2.8 1.8 2 0 0 2 2 2 0 PIG-P 5_nucleotid PF05761.9 KLO08074.1 - 0.15 10.5 0.5 0.16 10.4 0.3 1.1 1 0 0 1 1 1 0 5' nucleotidase family SOBP PF15279.1 KLO08074.1 - 0.89 9.8 5.8 0.92 9.8 4.0 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein WD40 PF00400.27 KLO08075.1 - 5.6e-61 200.4 15.5 2.1e-11 43.2 0.1 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat eIF2A PF08662.6 KLO08075.1 - 9.4e-08 31.9 0.0 0.0038 16.9 0.0 2.7 1 1 1 3 3 3 3 Eukaryotic translation initiation factor eIF2A Nucleoporin_N PF08801.6 KLO08075.1 - 0.00035 19.4 0.0 0.29 9.8 0.0 3.5 1 1 3 4 4 4 2 Nup133 N terminal like Coatomer_WDAD PF04053.9 KLO08075.1 - 0.00038 19.3 0.0 0.00055 18.8 0.0 1.1 1 0 0 1 1 1 1 Coatomer WD associated region Det1 PF09737.4 KLO08075.1 - 0.0061 15.3 0.0 0.0091 14.8 0.0 1.1 1 0 0 1 1 1 1 De-etiolated protein 1 Det1 DUF1724 PF08350.5 KLO08076.1 - 0.21 11.1 1.3 10 5.7 0.0 2.5 2 1 1 3 3 3 0 Domain of unknown function (DUF1724) Nop14 PF04147.7 KLO08076.1 - 0.75 7.6 11.5 0.74 7.6 8.0 1.0 1 0 0 1 1 1 0 Nop14-like family TRAP_alpha PF03896.11 KLO08076.1 - 3.2 6.6 7.0 3.5 6.5 4.9 1.1 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Nucleoplasmin PF03066.10 KLO08076.1 - 3.7 7.0 16.6 4.1 6.9 10.8 1.7 1 1 0 1 1 1 0 Nucleoplasmin F-box-like PF12937.2 KLO08077.1 - 0.0057 16.3 0.0 0.02 14.5 0.0 2.1 1 0 0 1 1 1 1 F-box-like DUF86 PF01934.12 KLO08078.1 - 0.021 14.4 0.1 0.063 12.9 0.1 1.8 1 1 1 2 2 2 0 Protein of unknown function DUF86 Vpu PF00558.14 KLO08078.1 - 0.14 11.7 0.1 0.26 10.8 0.1 1.4 1 0 0 1 1 1 0 Vpu protein zinc_ribbon_2 PF13240.1 KLO08078.1 - 0.18 11.3 0.7 0.36 10.3 0.1 1.8 2 0 0 2 2 2 0 zinc-ribbon domain DUF2682 PF10909.3 KLO08079.1 - 0.061 13.6 0.4 0.55 10.5 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2682) Phage_mat-A PF03863.8 KLO08079.1 - 0.084 11.9 0.1 0.12 11.3 0.1 1.2 1 0 0 1 1 1 0 Phage maturation protein PMEI PF04043.10 KLO08079.1 - 4.4 7.2 6.3 2.6 7.9 0.1 2.7 2 1 0 3 3 3 0 Plant invertase/pectin methylesterase inhibitor BIR PF00653.16 KLO08080.1 - 0.0015 18.8 1.3 0.0027 18.0 0.9 1.5 1 1 0 1 1 1 1 Inhibitor of Apoptosis domain DZR PF12773.2 KLO08080.1 - 0.0034 17.1 0.3 0.0047 16.7 0.2 1.3 1 0 0 1 1 1 1 Double zinc ribbon UPF0547 PF10571.4 KLO08080.1 - 0.035 13.7 0.9 0.17 11.6 0.6 1.9 2 0 0 2 2 2 0 Uncharacterised protein family UPF0547 zinc_ribbon_2 PF13240.1 KLO08080.1 - 0.039 13.4 0.7 0.071 12.6 0.5 1.5 1 0 0 1 1 1 0 zinc-ribbon domain C1_1 PF00130.17 KLO08080.1 - 0.05 13.3 1.2 0.065 12.9 0.5 1.4 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) RPA_interact_C PF14768.1 KLO08080.1 - 0.051 13.9 0.4 0.085 13.2 0.2 1.4 1 1 0 1 1 1 0 Replication protein A interacting C-terminal zinc-ribbons_6 PF07191.7 KLO08080.1 - 0.066 13.0 0.4 0.12 12.1 0.3 1.3 1 0 0 1 1 1 0 zinc-ribbons RGP PF03214.8 KLO08080.1 - 0.098 11.3 0.0 0.11 11.2 0.0 1.1 1 0 0 1 1 1 0 Reversibly glycosylated polypeptide zf-ribbon_3 PF13248.1 KLO08080.1 - 0.099 11.8 1.3 0.12 11.6 0.1 1.7 2 0 0 2 2 2 0 zinc-ribbon domain DNA_RNApol_7kD PF03604.8 KLO08080.1 - 0.22 11.0 2.1 0.38 10.2 1.4 1.4 1 0 0 1 1 1 0 DNA directed RNA polymerase, 7 kDa subunit zf-RING_3 PF14369.1 KLO08080.1 - 0.3 11.1 3.1 5.4 7.1 0.5 2.4 1 1 1 2 2 2 0 zinc-finger UPF0154 PF03672.8 KLO08082.1 - 0.12 11.9 0.0 0.26 10.9 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0154) RasGEF PF00617.14 KLO08083.1 - 8.4e-49 165.8 0.0 1.4e-48 165.1 0.0 1.3 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.15 KLO08083.1 - 6.3e-18 64.7 0.0 1.5e-17 63.5 0.0 1.7 1 0 0 1 1 1 1 RasGEF N-terminal motif DUF896 PF05979.7 KLO08083.1 - 0.085 12.4 0.0 0.2 11.2 0.0 1.6 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF896) F-box-like PF12937.2 KLO08087.1 - 0.0046 16.6 0.1 0.01 15.5 0.0 1.7 1 0 0 1 1 1 1 F-box-like FAM180 PF15173.1 KLO08087.1 - 0.06 13.1 0.0 0.13 11.9 0.0 1.5 1 0 0 1 1 1 0 FAM180 family F-box-like PF12937.2 KLO08088.1 - 3.7e-05 23.3 0.1 0.0004 20.0 0.0 2.8 1 1 0 1 1 1 1 F-box-like F-box-like PF12937.2 KLO08089.1 - 2.5e-06 27.1 0.1 7.5e-06 25.5 0.0 1.9 1 0 0 1 1 1 1 F-box-like ApbA_C PF08546.6 KLO08089.1 - 0.061 13.3 0.0 0.31 11.0 0.0 2.1 2 1 0 2 2 2 0 Ketopantoate reductase PanE/ApbA C terminal Cwf_Cwc_15 PF04889.7 KLO08090.1 - 0.051 13.2 8.3 0.072 12.7 5.7 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein DUF2763 PF10961.3 KLO08092.1 - 0.13 12.6 0.1 0.28 11.6 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2763) F-box-like PF12937.2 KLO08093.1 - 1.9e-06 27.5 0.0 6.9e-06 25.6 0.0 2.1 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 KLO08093.1 - 0.00011 21.6 0.0 0.00042 19.8 0.0 2.1 1 0 0 1 1 1 1 F-box domain DUF3521 PF12035.3 KLO08093.1 - 0.033 14.0 0.1 0.36 10.6 0.1 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3521) F-box-like PF12937.2 KLO08097.1 - 4.4e-11 42.3 0.1 6.2e-10 38.6 0.0 2.5 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 KLO08097.1 - 2.9e-05 23.5 0.0 0.00012 21.6 0.0 2.2 1 0 0 1 1 1 1 F-box domain Mu-like_gpT PF10124.4 KLO08100.1 - 0.088 11.7 0.0 0.088 11.7 0.0 1.1 1 0 0 1 1 1 0 Mu-like prophage major head subunit gpT Pertussis_S2S3 PF02918.10 KLO08103.1 - 0.054 13.2 0.4 0.13 11.9 0.2 1.8 1 1 0 1 1 1 0 Pertussis toxin, subunit 2 and 3, C-terminal domain FBPase_glpX PF03320.8 KLO08103.1 - 0.15 10.7 0.1 0.23 10.0 0.1 1.3 1 0 0 1 1 1 0 Bacterial fructose-1,6-bisphosphatase, glpX-encoded HMG_box PF00505.14 KLO08106.1 - 2.1e-10 40.7 0.0 4.6e-10 39.6 0.0 1.6 1 0 0 1 1 1 1 HMG (high mobility group) box gag_pre-integrs PF13976.1 KLO08110.1 - 6.8e-10 38.4 0.0 9.4e-10 37.9 0.0 1.3 1 0 0 1 1 1 1 GAG-pre-integrase domain UBN2_2 PF14227.1 KLO08111.1 - 1.8e-12 46.8 0.0 2.5e-12 46.3 0.0 1.2 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type UBN2 PF14223.1 KLO08111.1 - 7.7e-12 45.0 0.0 1e-11 44.6 0.0 1.1 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type DUF1556 PF07590.6 KLO08111.1 - 0.13 12.5 0.1 0.25 11.5 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1556) HET PF06985.6 KLO08112.1 - 9.6e-07 29.0 0.7 0.00036 20.7 0.0 2.4 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) Pkinase PF00069.20 KLO08113.1 - 1.6e-05 24.1 0.0 0.00015 21.0 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain APH PF01636.18 KLO08113.1 - 0.00013 21.8 0.1 0.00027 20.7 0.1 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family APH PF01636.18 KLO08114.1 - 0.00021 21.1 0.1 0.00068 19.4 0.0 1.8 2 0 0 2 2 2 1 Phosphotransferase enzyme family Pkinase PF00069.20 KLO08114.1 - 0.00044 19.4 0.0 0.00077 18.6 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase PF00069.20 KLO08116.1 - 4.8e-05 22.6 0.0 9.9e-05 21.6 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain APH PF01636.18 KLO08116.1 - 0.00039 20.2 0.0 0.00079 19.2 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_Tyr PF07714.12 KLO08116.1 - 0.038 13.0 0.0 0.07 12.1 0.0 1.3 1 0 0 1 1 1 0 Protein tyrosine kinase Fungal_trans_2 PF11951.3 KLO08116.1 - 0.11 11.1 0.0 0.18 10.3 0.0 1.3 1 0 0 1 1 1 0 Fungal specific transcription factor domain bZIP_1 PF00170.16 KLO08119.1 - 1.1e-06 28.4 5.6 2.1e-06 27.5 3.9 1.4 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 KLO08119.1 - 0.00083 19.1 10.0 0.0015 18.2 6.9 1.4 1 0 0 1 1 1 1 Basic region leucine zipper Spt5_N PF11942.3 KLO08119.1 - 0.051 14.2 5.0 0.12 12.9 3.5 1.6 1 0 0 1 1 1 0 Spt5 transcription elongation factor, acidic N-terminal bZIP_Maf PF03131.12 KLO08119.1 - 0.051 13.8 3.2 0.11 12.7 2.2 1.5 1 0 0 1 1 1 0 bZIP Maf transcription factor GDA1_CD39 PF01150.12 KLO08121.1 - 7.5e-90 301.4 0.0 1e-89 301.0 0.0 1.0 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family Pyr_redox_2 PF07992.9 KLO08122.1 - 5.1e-29 101.5 0.1 6.1e-29 101.3 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 KLO08122.1 - 2.4e-17 63.1 0.2 2.4e-14 53.4 0.0 2.8 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 KLO08122.1 - 8.2e-08 32.5 0.0 0.00013 22.1 0.0 2.7 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 KLO08122.1 - 3.6e-06 26.2 0.1 3.4e-05 23.0 0.0 2.2 2 0 0 2 2 2 1 Thi4 family DAO PF01266.19 KLO08122.1 - 5.9e-06 25.4 0.1 0.0085 15.0 0.1 3.2 2 1 0 3 3 3 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 KLO08122.1 - 1.5e-05 24.0 1.3 0.002 17.0 0.1 2.5 2 0 0 2 2 2 2 FAD binding domain GIDA PF01134.17 KLO08122.1 - 3.5e-05 22.8 4.5 0.0048 15.7 0.0 3.9 4 1 1 5 5 5 1 Glucose inhibited division protein A Shikimate_DH PF01488.15 KLO08122.1 - 7.6e-05 22.8 0.1 0.099 12.7 0.0 2.6 2 1 0 2 2 2 2 Shikimate / quinate 5-dehydrogenase NAD_binding_8 PF13450.1 KLO08122.1 - 0.00021 21.2 0.1 0.013 15.5 0.0 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.2 KLO08122.1 - 0.00088 18.4 0.5 0.024 13.6 0.0 2.6 3 0 0 3 3 3 1 FAD dependent oxidoreductase NAD_binding_7 PF13241.1 KLO08122.1 - 0.0019 18.4 0.1 0.13 12.4 0.0 2.8 2 1 0 2 2 2 1 Putative NAD(P)-binding Trp_halogenase PF04820.9 KLO08122.1 - 0.0029 16.2 0.4 0.053 12.1 0.2 2.5 2 1 1 3 3 3 1 Tryptophan halogenase FAD_binding_3 PF01494.14 KLO08122.1 - 0.0041 16.2 0.1 0.05 12.6 0.0 2.1 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.9 KLO08122.1 - 0.0088 14.5 0.3 0.041 12.3 0.1 2.1 2 0 0 2 2 2 1 HI0933-like protein K_oxygenase PF13434.1 KLO08122.1 - 0.01 14.7 0.0 2.1 7.2 0.0 3.4 2 1 1 4 4 4 0 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.1 KLO08122.1 - 0.014 15.1 0.1 9.8 5.9 0.2 2.9 2 0 0 2 2 2 0 FAD-NAD(P)-binding F420_oxidored PF03807.12 KLO08122.1 - 0.019 15.3 0.0 2.8 8.4 0.0 3.0 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent NAD_Gly3P_dh_N PF01210.18 KLO08122.1 - 0.055 13.2 0.2 2.7 7.6 0.1 2.5 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus ThiF PF00899.16 KLO08122.1 - 0.07 12.9 0.0 0.34 10.7 0.0 2.1 3 0 0 3 3 3 0 ThiF family ApbA PF02558.11 KLO08122.1 - 0.12 11.7 0.4 15 5.0 0.0 2.6 2 1 0 2 2 2 0 Ketopantoate reductase PanE/ApbA FMN_dh PF01070.13 KLO08123.1 - 3.5e-112 374.7 0.0 4.1e-112 374.5 0.0 1.0 1 0 0 1 1 1 1 FMN-dependent dehydrogenase IMPDH PF00478.20 KLO08123.1 - 9.7e-05 21.4 0.1 0.00067 18.6 0.0 2.2 3 0 0 3 3 3 1 IMP dehydrogenase / GMP reductase domain ThiG PF05690.9 KLO08123.1 - 0.00032 19.8 0.7 0.11 11.5 0.0 3.3 3 1 0 4 4 4 1 Thiazole biosynthesis protein ThiG Glu_synthase PF01645.12 KLO08123.1 - 0.00038 19.4 0.1 0.00066 18.7 0.1 1.3 1 0 0 1 1 1 1 Conserved region in glutamate synthase Glycos_transf_1 PF00534.15 KLO08124.1 - 9.9e-25 86.9 0.0 1.5e-24 86.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.1 KLO08124.1 - 9e-11 42.0 0.0 4.2e-10 39.8 0.0 2.0 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.1 KLO08124.1 - 0.03 14.5 0.0 0.067 13.4 0.0 1.6 1 0 0 1 1 1 0 Glycosyl transferases group 1 Abhydrolase_6 PF12697.2 KLO08125.1 - 1.6e-28 100.1 0.0 2.3e-28 99.6 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KLO08125.1 - 1.7e-14 53.7 0.0 6.7e-14 51.8 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KLO08125.1 - 2.5e-12 46.8 0.0 4.3e-12 46.0 0.0 1.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.3 KLO08125.1 - 0.00013 21.7 0.0 0.00024 20.8 0.0 1.4 1 0 0 1 1 1 1 Putative lysophospholipase Peptidase_S9 PF00326.16 KLO08125.1 - 0.0071 15.5 0.0 0.02 14.1 0.0 1.7 2 0 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_2 PF02230.11 KLO08125.1 - 0.018 14.5 0.0 0.11 11.8 0.0 2.0 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Yae1_N PF09811.4 KLO08127.1 - 3e-10 39.4 12.1 8.4e-05 22.0 0.2 2.3 1 1 1 2 2 2 2 Essential protein Yae1, N terminal DUF745 PF05335.8 KLO08127.1 - 0.00021 20.8 15.6 0.0003 20.3 10.8 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF745) V_ATPase_I PF01496.14 KLO08127.1 - 0.00094 17.1 6.9 0.0013 16.6 4.8 1.1 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family DUF641 PF04859.7 KLO08127.1 - 0.0025 17.5 8.5 0.0046 16.7 5.9 1.5 1 0 0 1 1 1 1 Plant protein of unknown function (DUF641) Myosin_tail_1 PF01576.14 KLO08127.1 - 0.0033 15.2 24.1 0.0046 14.7 16.7 1.1 1 0 0 1 1 1 1 Myosin tail Syntaxin PF00804.20 KLO08127.1 - 0.026 14.6 6.0 0.026 14.6 4.2 2.1 1 1 1 2 2 2 0 Syntaxin DUF3450 PF11932.3 KLO08127.1 - 0.06 12.6 15.4 0.032 13.4 9.2 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) Tropomyosin PF00261.15 KLO08127.1 - 0.064 12.3 22.7 0.025 13.6 12.5 2.1 1 1 0 1 1 1 0 Tropomyosin Spc7 PF08317.6 KLO08127.1 - 0.35 9.4 14.7 0.47 9.0 10.2 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein Fmp27_WPPW PF10359.4 KLO08127.1 - 0.45 8.8 8.1 0.59 8.4 5.6 1.1 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain AAA_13 PF13166.1 KLO08127.1 - 0.58 8.5 7.4 0.76 8.1 5.1 1.1 1 0 0 1 1 1 0 AAA domain FUSC PF04632.7 KLO08127.1 - 0.68 8.2 9.8 0.78 8.0 6.8 1.0 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF4208 PF13907.1 KLO08127.1 - 0.69 10.1 3.4 17 5.6 0.1 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4208) DUF3584 PF12128.3 KLO08127.1 - 0.73 7.0 20.3 0.95 6.7 14.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) CCDC-167 PF15188.1 KLO08127.1 - 1.4 8.9 16.4 9.6 6.2 0.4 2.9 1 1 0 2 2 2 0 Coiled-coil domain-containing protein 167 Tropomyosin_1 PF12718.2 KLO08127.1 - 1.6 8.6 20.2 6.2 6.6 14.0 2.0 1 1 0 1 1 1 0 Tropomyosin like Mnd1 PF03962.10 KLO08127.1 - 1.6 8.3 14.8 4 7.0 10.2 1.7 1 1 0 1 1 1 0 Mnd1 family CENP-F_leu_zip PF10473.4 KLO08127.1 - 1.7 8.5 18.1 1 9.2 10.4 1.9 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 MscS_porin PF12795.2 KLO08127.1 - 2.6 7.2 24.0 8.2 5.6 16.7 1.7 1 1 0 1 1 1 0 Mechanosensitive ion channel porin domain DUF2229 PF09989.4 KLO08127.1 - 2.8 7.3 4.8 2.8 7.3 2.6 1.5 1 1 0 1 1 1 0 CoA enzyme activase uncharacterised domain (DUF2229) TMCO5 PF14992.1 KLO08127.1 - 4 6.4 13.0 5.5 6.0 9.0 1.1 1 0 0 1 1 1 0 TMCO5 family Sad1_UNC PF07738.8 KLO08128.1 - 1.7e-31 108.7 0.1 3.5e-31 107.8 0.0 1.5 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal Tmemb_cc2 PF10267.4 KLO08128.1 - 2.4 6.6 7.6 4.5 5.7 5.2 1.4 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein Macoilin PF09726.4 KLO08128.1 - 6.5 4.9 22.9 0.04 12.2 9.9 1.6 2 0 0 2 2 2 0 Transmembrane protein ATP-synt_C PF00137.16 KLO08129.1 - 6e-31 106.1 28.1 5e-18 64.7 8.4 2.1 2 0 0 2 2 2 2 ATP synthase subunit C DUF2970 PF11174.3 KLO08129.1 - 4.4 6.9 8.1 1.2 8.7 0.3 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2970) RCR PF12273.3 KLO08130.1 - 0.031 14.8 2.2 0.066 13.7 1.5 1.5 1 1 0 1 1 1 0 Chitin synthesis regulation, resistance to Congo red DUF912 PF06024.7 KLO08130.1 - 0.054 13.5 0.0 0.083 12.9 0.0 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) EphA2_TM PF14575.1 KLO08130.1 - 0.054 13.8 0.0 0.1 13.0 0.0 1.6 1 1 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Podoplanin PF05808.6 KLO08130.1 - 0.087 12.3 0.0 0.16 11.5 0.0 1.4 1 0 0 1 1 1 0 Podoplanin Myc_target_1 PF15179.1 KLO08130.1 - 0.11 12.0 1.5 0.28 10.7 1.1 1.6 1 1 0 1 1 1 0 Myc target protein 1 AAA PF00004.24 KLO08131.1 - 5.8e-39 133.3 0.0 8.9e-39 132.7 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 KLO08131.1 - 2.4e-07 30.0 0.0 1.6e-06 27.3 0.0 2.0 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_14 PF13173.1 KLO08131.1 - 2e-06 27.7 0.0 7.7e-06 25.8 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 KLO08131.1 - 1.1e-05 26.2 0.0 4.7e-05 24.1 0.0 2.1 2 0 0 2 2 1 1 AAA domain AAA_16 PF13191.1 KLO08131.1 - 1.5e-05 25.0 0.0 0.00037 20.5 0.0 2.4 1 1 1 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 KLO08131.1 - 2.5e-05 24.4 0.1 0.0005 20.2 0.0 2.2 1 1 1 2 2 2 1 AAA domain AAA_5 PF07728.9 KLO08131.1 - 3e-05 23.7 0.4 0.00058 19.5 0.3 2.7 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_33 PF13671.1 KLO08131.1 - 0.00026 20.8 0.0 0.00044 20.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.16 KLO08131.1 - 0.00026 20.2 0.2 0.0013 17.9 0.1 1.9 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI Zeta_toxin PF06414.7 KLO08131.1 - 0.00028 20.0 0.1 0.00046 19.3 0.0 1.2 1 0 0 1 1 1 1 Zeta toxin AAA_2 PF07724.9 KLO08131.1 - 0.00029 20.8 0.0 0.00055 19.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) Sigma54_activ_2 PF14532.1 KLO08131.1 - 0.00044 20.3 0.0 0.00087 19.3 0.0 1.4 1 0 0 1 1 1 1 Sigma-54 interaction domain IstB_IS21 PF01695.12 KLO08131.1 - 0.00076 18.9 0.1 0.0013 18.1 0.1 1.3 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_18 PF13238.1 KLO08131.1 - 0.00091 19.5 0.0 0.0018 18.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.17 KLO08131.1 - 0.0012 18.9 0.0 0.0028 17.8 0.0 1.7 2 0 0 2 2 1 1 RNA helicase AAA_25 PF13481.1 KLO08131.1 - 0.0019 17.6 0.5 0.039 13.3 0.2 2.3 1 1 0 2 2 2 1 AAA domain AAA_28 PF13521.1 KLO08131.1 - 0.0025 17.7 0.1 0.0057 16.6 0.0 1.6 2 0 0 2 2 1 1 AAA domain NACHT PF05729.7 KLO08131.1 - 0.0036 16.9 0.1 0.011 15.4 0.1 1.8 2 0 0 2 2 1 1 NACHT domain Rad17 PF03215.10 KLO08131.1 - 0.0037 16.0 0.0 0.0054 15.4 0.0 1.3 1 0 0 1 1 1 1 Rad17 cell cycle checkpoint protein TIP49 PF06068.8 KLO08131.1 - 0.0045 15.7 0.1 0.0085 14.8 0.0 1.5 1 0 0 1 1 1 1 TIP49 C-terminus AAA_24 PF13479.1 KLO08131.1 - 0.0049 16.4 0.0 0.0082 15.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain Bac_DnaA PF00308.13 KLO08131.1 - 0.0056 16.3 0.0 0.024 14.3 0.0 1.8 1 1 0 1 1 1 1 Bacterial dnaA protein Sigma54_activat PF00158.21 KLO08131.1 - 0.0074 15.7 0.0 0.038 13.4 0.0 2.0 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_10 PF12846.2 KLO08131.1 - 0.0079 15.6 0.2 1.4 8.2 0.0 2.3 1 1 1 2 2 2 1 AAA-like domain Arch_ATPase PF01637.13 KLO08131.1 - 0.019 14.6 0.0 0.1 12.2 0.0 2.0 1 1 0 2 2 2 0 Archaeal ATPase Parvo_NS1 PF01057.12 KLO08131.1 - 0.026 13.4 0.0 0.039 12.8 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 ABC_tran PF00005.22 KLO08131.1 - 0.034 14.4 0.0 0.065 13.5 0.0 1.5 1 0 0 1 1 1 0 ABC transporter AAA_19 PF13245.1 KLO08131.1 - 0.04 13.6 0.0 0.097 12.4 0.0 1.7 1 0 0 1 1 1 0 Part of AAA domain CPT PF07931.7 KLO08131.1 - 0.045 13.3 0.0 0.086 12.4 0.0 1.5 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein Viral_helicase1 PF01443.13 KLO08131.1 - 0.045 13.2 0.0 0.065 12.7 0.0 1.2 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase DUF815 PF05673.8 KLO08131.1 - 0.046 12.6 0.0 0.076 11.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) KaiC PF06745.8 KLO08131.1 - 0.05 12.7 0.0 0.59 9.2 0.0 2.1 1 1 1 2 2 2 0 KaiC AAA_3 PF07726.6 KLO08131.1 - 0.053 13.1 0.0 0.11 12.0 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) UPF0079 PF02367.12 KLO08131.1 - 0.056 13.0 0.0 0.1 12.2 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 AAA_21 PF13304.1 KLO08131.1 - 0.059 13.3 0.1 8.6 6.2 0.0 2.5 1 1 1 2 2 2 0 AAA domain Guanylate_kin PF00625.16 KLO08131.1 - 0.07 12.5 0.0 0.2 11.0 0.0 1.8 2 0 0 2 2 2 0 Guanylate kinase SKI PF01202.17 KLO08131.1 - 0.07 12.9 0.1 0.15 11.9 0.0 1.5 1 0 0 1 1 1 0 Shikimate kinase NB-ARC PF00931.17 KLO08131.1 - 0.09 11.6 0.0 0.15 10.8 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain ATP-synt_ab PF00006.20 KLO08131.1 - 0.1 12.1 0.0 0.12 11.7 0.0 1.2 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain Tetraspannin PF00335.15 KLO08132.1 - 2.6e-13 49.7 6.1 3.5e-13 49.3 4.2 1.1 1 0 0 1 1 1 1 Tetraspanin family DUF1422 PF07226.6 KLO08132.1 - 1.2 8.8 5.9 1.2 8.8 1.3 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF1422) HTH_Tnp_ISL3 PF13542.1 KLO08134.1 - 0.17 11.0 0.7 13 5.1 0.0 3.1 3 0 0 3 3 3 0 Helix-turn-helix domain of transposase family ISL3 Zip PF02535.17 KLO08139.1 - 1.9e-41 142.1 27.5 8.3e-41 140.0 19.1 1.8 1 1 0 1 1 1 1 ZIP Zinc transporter DUF373 PF04123.8 KLO08139.1 - 3.8 6.4 9.3 6.3 5.7 6.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF373) Adap_comp_sub PF00928.16 KLO08141.1 - 0.16 11.0 0.0 0.31 10.1 0.0 1.4 1 0 0 1 1 1 0 Adaptor complexes medium subunit family BTB_2 PF02214.17 KLO08143.1 - 9e-06 25.8 0.1 0.0002 21.5 0.0 2.4 2 0 0 2 2 2 1 BTB/POZ domain Yae1_N PF09811.4 KLO08144.1 - 2.5e-09 36.5 7.6 3.6e-09 36.0 5.3 1.2 1 0 0 1 1 1 1 Essential protein Yae1, N terminal Cu_amine_oxid PF01179.15 KLO08145.1 - 4.9e-151 503.1 0.0 6.2e-151 502.8 0.0 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN3 PF02728.11 KLO08145.1 - 3.3e-14 52.7 0.0 6.7e-14 51.7 0.0 1.5 1 0 0 1 1 1 1 Copper amine oxidase, N3 domain Cu_amine_oxidN2 PF02727.11 KLO08145.1 - 0.00015 21.7 0.0 0.00032 20.7 0.0 1.5 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain Hydrolase_like2 PF13246.1 KLO08145.1 - 0.18 11.8 0.0 0.37 10.7 0.0 1.5 1 0 0 1 1 1 0 Putative hydrolase of sodium-potassium ATPase alpha subunit Pro_isomerase PF00160.16 KLO08146.1 - 1.1e-44 152.4 0.5 1.2e-44 152.2 0.3 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD EOS1 PF12326.3 KLO08147.1 - 1.1e-18 67.3 2.5 2.2e-18 66.3 1.8 1.5 1 0 0 1 1 1 1 N-glycosylation protein Nha1_C PF08619.5 KLO08147.1 - 0.00079 18.8 0.4 0.0012 18.1 0.3 1.3 1 1 0 1 1 1 1 Alkali metal cation/H+ antiporter Nha1 C terminus Saccharop_dh PF03435.13 KLO08148.1 - 9.2e-75 252.0 0.0 1.2e-74 251.6 0.0 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase AlaDh_PNT_C PF01262.16 KLO08148.1 - 2.2e-12 46.8 0.5 6.7e-12 45.2 0.0 2.1 3 0 0 3 3 3 1 Alanine dehydrogenase/PNT, C-terminal domain AlaDh_PNT_N PF05222.10 KLO08148.1 - 3.4e-07 30.3 0.0 2.2e-06 27.7 0.0 2.5 4 0 0 4 4 4 1 Alanine dehydrogenase/PNT, N-terminal domain Ribonuclease_T2 PF00445.13 KLO08149.1 - 1.1e-36 126.3 1.0 1.7e-36 125.6 0.7 1.3 1 0 0 1 1 1 1 Ribonuclease T2 family Deltaretro_Tax PF05599.6 KLO08150.1 - 0.25 11.6 2.1 0.28 11.4 0.2 2.0 1 1 1 2 2 2 0 Deltaretrovirus Tax protein adh_short PF00106.20 KLO08151.1 - 1.8e-20 73.4 0.7 3.5e-20 72.5 0.1 1.6 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.1 KLO08151.1 - 1.4e-09 38.0 0.2 1.8e-09 37.7 0.2 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KLO08151.1 - 1.5e-06 28.0 0.1 2e-06 27.6 0.1 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 KLO08151.1 - 0.00021 20.8 0.0 0.0032 16.9 0.0 2.0 1 1 1 2 2 2 1 NAD dependent epimerase/dehydratase family NmrA PF05368.8 KLO08151.1 - 0.0044 16.3 0.0 0.0096 15.2 0.0 1.5 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 KLO08151.1 - 0.0059 16.6 0.2 0.0092 15.9 0.1 1.6 1 1 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 KLO08151.1 - 0.06 12.0 0.0 0.083 11.5 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Abhydrolase_3 PF07859.8 KLO08152.1 - 2.7e-14 53.2 0.1 5.2e-13 49.0 0.1 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.23 KLO08152.1 - 1.1e-09 37.6 0.2 7.2e-09 34.8 0.1 1.9 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_5 PF12695.2 KLO08152.1 - 1.6e-07 31.2 0.0 2e-07 30.8 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KLO08152.1 - 3.5e-07 30.3 0.1 4.9e-07 29.8 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 KLO08152.1 - 0.0003 20.0 0.0 0.0057 15.8 0.0 2.4 2 1 0 2 2 2 1 Prolyl oligopeptidase family DUF2424 PF10340.4 KLO08152.1 - 0.00044 19.0 0.0 0.00063 18.4 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2424) Abhydrolase_1 PF00561.15 KLO08152.1 - 0.014 14.9 0.0 0.014 14.9 0.0 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold DIM1 PF02966.11 KLO08153.1 - 2.6e-59 198.5 0.2 3e-59 198.3 0.2 1.0 1 0 0 1 1 1 1 Mitosis protein DIM1 TFIIS_M PF07500.9 KLO08154.1 - 6.3e-31 106.8 0.6 2.6e-30 104.8 0.0 2.1 2 0 0 2 2 2 1 Transcription factor S-II (TFIIS), central domain TFIIS_C PF01096.13 KLO08154.1 - 1.2e-16 60.0 8.6 1.8e-16 59.4 6.0 1.3 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS) Med26 PF08711.6 KLO08154.1 - 1.3e-15 56.6 0.9 2.6e-15 55.6 0.6 1.6 1 0 0 1 1 1 1 TFIIS helical bundle-like domain HMG_box PF00505.14 KLO08154.1 - 0.31 11.3 2.8 0.3 11.3 0.4 2.1 2 0 0 2 2 2 0 HMG (high mobility group) box zinc_ribbon_5 PF13719.1 KLO08154.1 - 0.54 9.8 4.6 4.1 7.0 0.3 3.0 3 0 0 3 3 3 0 zinc-ribbon domain zinc_ribbon_4 PF13717.1 KLO08154.1 - 0.67 9.7 4.3 6.6 6.5 0.3 3.0 3 0 0 3 3 3 0 zinc-ribbon domain Rad60-SLD PF11976.3 KLO08155.1 - 4.9e-23 80.6 0.8 6.1e-23 80.3 0.6 1.1 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.18 KLO08155.1 - 2.1e-08 33.4 0.3 2.6e-08 33.1 0.2 1.2 1 0 0 1 1 1 1 Ubiquitin family DUF3596 PF12167.3 KLO08155.1 - 0.13 11.7 0.0 12 5.4 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3596) adh_short PF00106.20 KLO08157.1 - 7.8e-20 71.4 0.1 9.4e-20 71.1 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KLO08157.1 - 6.2e-08 32.6 0.2 7.6e-08 32.4 0.2 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KLO08157.1 - 1.5e-05 24.7 0.1 2.1e-05 24.2 0.1 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_4 PF07993.7 KLO08157.1 - 0.00095 18.1 0.1 0.0028 16.6 0.1 1.7 1 1 0 1 1 1 1 Male sterility protein Epimerase PF01370.16 KLO08157.1 - 0.063 12.6 0.1 0.1 12.0 0.0 1.5 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Abhydrolase_3 PF07859.8 KLO08158.1 - 2.2e-13 50.2 0.1 3.8e-12 46.2 0.1 2.3 1 1 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.23 KLO08158.1 - 1.5e-08 33.8 0.2 6.1e-08 31.8 0.1 1.8 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_5 PF12695.2 KLO08158.1 - 3.1e-07 30.2 0.0 4.5e-07 29.7 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KLO08158.1 - 9.3e-06 25.6 0.4 1.8e-05 24.7 0.3 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 KLO08158.1 - 1e-05 24.8 0.0 2e-05 23.9 0.0 1.6 1 1 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_1 PF00561.15 KLO08158.1 - 2e-05 24.2 0.0 2.9e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF2424 PF10340.4 KLO08158.1 - 0.00078 18.1 0.0 0.001 17.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2424) Cutinase PF01083.17 KLO08158.1 - 0.0062 16.2 0.0 0.13 11.9 0.0 2.1 2 0 0 2 2 2 1 Cutinase PCP PF02429.10 KLO08158.1 - 0.046 13.8 0.0 0.08 13.0 0.0 1.3 1 0 0 1 1 1 0 Peridinin-chlorophyll A binding protein PGAP1 PF07819.8 KLO08158.1 - 0.11 12.0 0.0 0.16 11.5 0.0 1.2 1 0 0 1 1 1 0 PGAP1-like protein DUF2974 PF11187.3 KLO08158.1 - 0.18 11.1 0.0 0.27 10.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) DPPIV_N PF00930.16 KLO08161.1 - 0.048 12.2 0.0 0.34 9.4 0.0 2.1 1 1 1 2 2 2 0 Dipeptidyl peptidase IV (DPP IV) N-terminal region DUF3022 PF11226.3 KLO08163.1 - 0.11 12.3 0.1 0.21 11.4 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3022) BCIP PF13862.1 KLO08164.1 - 3.3e-57 193.1 0.0 5e-57 192.5 0.0 1.2 1 0 0 1 1 1 1 p21-C-terminal region-binding protein DIOX_N PF14226.1 KLO08165.1 - 0.0017 18.8 0.2 0.0045 17.5 0.1 1.7 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 KLO08165.1 - 0.011 16.0 0.0 0.027 14.7 0.0 1.6 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily AAA_17 PF13207.1 KLO08167.1 - 3.1e-05 24.7 0.1 0.00014 22.6 0.1 2.0 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 KLO08167.1 - 5.5e-05 23.4 0.0 0.024 14.9 0.0 2.2 2 0 0 2 2 2 2 AAA domain AAA_33 PF13671.1 KLO08167.1 - 0.0011 18.8 0.2 0.0092 15.8 0.0 2.1 2 0 0 2 2 2 1 AAA domain ArgK PF03308.11 KLO08167.1 - 0.0011 17.7 0.0 0.0016 17.3 0.0 1.2 1 0 0 1 1 1 1 ArgK protein KTI12 PF08433.5 KLO08167.1 - 0.02 14.1 0.0 0.042 13.0 0.0 1.5 2 0 0 2 2 2 0 Chromatin associated protein KTI12 NTPase_1 PF03266.10 KLO08167.1 - 0.059 13.0 0.0 0.096 12.3 0.0 1.3 1 0 0 1 1 1 0 NTPase Herpes_gE PF02480.11 KLO08168.1 - 0.019 13.2 0.1 0.024 12.9 0.0 1.2 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E SKG6 PF08693.5 KLO08168.1 - 0.068 12.4 0.3 0.17 11.1 0.2 1.7 1 0 0 1 1 1 0 Transmembrane alpha-helix domain FAD_binding_4 PF01565.18 KLO08170.1 - 1.8e-15 56.6 0.1 5.3e-15 55.1 0.1 1.8 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 KLO08170.1 - 2.6e-10 40.0 0.0 5.5e-10 38.9 0.0 1.5 1 0 0 1 1 1 1 Berberine and berberine like Cytokin-bind PF09265.5 KLO08170.1 - 0.068 12.3 0.0 0.1 11.7 0.0 1.2 1 0 0 1 1 1 0 Cytokinin dehydrogenase 1, FAD and cytokinin binding SKG6 PF08693.5 KLO08173.1 - 0.0056 15.9 0.8 0.016 14.5 0.6 1.8 1 0 0 1 1 1 1 Transmembrane alpha-helix domain PspC PF04024.7 KLO08173.1 - 0.084 12.3 0.6 0.22 11.0 0.4 1.6 1 0 0 1 1 1 0 PspC domain Syndecan PF01034.15 KLO08173.1 - 0.24 11.1 0.1 0.58 9.8 0.0 1.6 1 0 0 1 1 1 0 Syndecan domain DUF2273 PF10031.4 KLO08173.1 - 0.56 9.8 3.4 1 9.0 2.4 1.3 1 0 0 1 1 1 0 Small integral membrane protein (DUF2273) SKG6 PF08693.5 KLO08174.1 - 0.035 13.4 0.2 0.069 12.4 0.2 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Syndecan PF01034.15 KLO08174.1 - 0.042 13.5 0.0 0.074 12.7 0.0 1.3 1 0 0 1 1 1 0 Syndecan domain Gly-zipper_OmpA PF13436.1 KLO08174.1 - 0.062 12.9 0.1 0.19 11.4 0.1 1.8 1 0 0 1 1 1 0 Glycine-zipper containing OmpA-like membrane domain Hydrophobin PF01185.13 KLO08175.1 - 2e-07 31.3 0.5 2.7e-07 30.9 0.3 1.1 1 0 0 1 1 1 1 Fungal hydrophobin Collar PF07484.7 KLO08175.1 - 0.11 12.3 0.1 0.16 11.7 0.0 1.2 1 0 0 1 1 1 0 Phage Tail Collar Domain BTB PF00651.26 KLO08177.1 - 6.5e-09 35.7 0.0 1.3e-08 34.8 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain F-box-like PF12937.2 KLO08180.1 - 7.4e-06 25.5 0.0 2e-05 24.2 0.0 1.7 1 0 0 1 1 1 1 F-box-like CRIC_ras_sig PF10534.4 KLO08180.1 - 0.12 12.4 0.7 0.36 10.9 0.1 2.1 2 0 0 2 2 2 0 Connector enhancer of kinase suppressor of ras BTB PF00651.26 KLO08182.1 - 0.00033 20.6 0.1 0.00065 19.6 0.1 1.4 1 0 0 1 1 1 1 BTB/POZ domain Bromodomain PF00439.20 KLO08183.1 - 2.1e-29 101.2 0.4 1.6e-18 66.4 0.1 2.4 2 0 0 2 2 2 2 Bromodomain BAH PF01426.13 KLO08183.1 - 2.5e-08 33.7 0.0 4.5e-08 32.8 0.0 1.4 1 0 0 1 1 1 1 BAH domain Sec31 PF11549.3 KLO08184.1 - 0.02 14.5 0.0 0.045 13.4 0.0 1.6 1 0 0 1 1 1 0 Protein transport protein SEC31 WD40 PF00400.27 KLO08185.1 - 1.8e-40 135.4 14.1 5e-10 38.8 0.1 7.3 7 0 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 KLO08185.1 - 2.1e-09 36.0 2.9 0.0007 17.8 0.0 3.7 3 1 1 4 4 4 3 Nucleoporin Nup120/160 Jnk-SapK_ap_N PF09744.4 KLO08185.1 - 0.14 12.1 6.6 0.24 11.3 4.6 1.4 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 BC10 PF06726.7 KLO08186.1 - 1.7e-11 43.9 10.5 3.1e-11 43.1 7.3 1.4 1 0 0 1 1 1 1 Bladder cancer-related protein BC10 GTPase_binding PF09027.5 KLO08192.1 - 0.066 12.8 0.0 0.14 11.7 0.0 1.5 1 0 0 1 1 1 0 GTPase binding Daxx PF03344.10 KLO08202.1 - 0.069 11.6 5.2 0.072 11.5 3.6 1.1 1 0 0 1 1 1 0 Daxx Family CDC45 PF02724.9 KLO08202.1 - 0.11 10.5 4.8 0.11 10.4 3.3 1.0 1 0 0 1 1 1 0 CDC45-like protein MIP-T3 PF10243.4 KLO08202.1 - 0.12 10.8 2.4 0.14 10.5 1.7 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 HSP90 PF00183.13 KLO08202.1 - 0.27 9.5 4.1 0.33 9.3 2.9 1.1 1 0 0 1 1 1 0 Hsp90 protein Nop14 PF04147.7 KLO08202.1 - 0.66 7.8 10.3 0.71 7.7 7.1 1.0 1 0 0 1 1 1 0 Nop14-like family TRAP_alpha PF03896.11 KLO08202.1 - 1.3 7.9 5.0 1.6 7.6 3.5 1.1 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit DUF2457 PF10446.4 KLO08202.1 - 1.9 7.1 16.8 2.4 6.7 11.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) PPP4R2 PF09184.6 KLO08202.1 - 2.3 7.6 8.5 2.8 7.4 5.9 1.2 1 0 0 1 1 1 0 PPP4R2 BTB PF00651.26 KLO08207.1 - 2.8e-05 24.0 0.1 5.3e-05 23.1 0.1 1.6 1 1 0 1 1 1 1 BTB/POZ domain Pkinase PF00069.20 KLO08209.1 - 1.3e-37 129.4 0.0 1.6e-37 129.0 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KLO08209.1 - 1.7e-29 102.6 0.0 2.2e-29 102.3 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.17 KLO08209.1 - 0.0093 15.3 0.0 0.018 14.3 0.0 1.5 2 0 0 2 2 2 1 RIO1 family DUF3189 PF11385.3 KLO08209.1 - 0.084 12.4 0.0 0.16 11.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3189) APH PF01636.18 KLO08209.1 - 0.1 12.3 0.0 0.65 9.6 0.0 1.9 2 0 0 2 2 2 0 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.6 KLO08209.1 - 0.13 11.0 0.0 0.19 10.4 0.0 1.3 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase UvdE PF03851.9 KLO08210.1 - 5e-78 261.9 0.1 4.4e-67 226.0 0.0 2.8 2 1 0 2 2 2 2 UV-endonuclease UvdE AP_endonuc_2 PF01261.19 KLO08210.1 - 9.3e-05 21.8 0.0 0.00019 20.8 0.0 1.4 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel BTB PF00651.26 KLO08211.1 - 1.2e-08 34.9 0.3 1e-07 31.9 0.2 2.0 1 1 0 1 1 1 1 BTB/POZ domain CDP-OH_P_transf PF01066.16 KLO08212.1 - 4.5e-17 62.2 3.0 4.5e-17 62.2 2.1 2.4 2 1 1 3 3 3 1 CDP-alcohol phosphatidyltransferase DUF3816 PF12822.2 KLO08212.1 - 0.029 14.2 4.3 0.034 14.0 1.8 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3816) DUF3068 PF11271.3 KLO08213.1 - 0.039 13.0 0.0 0.067 12.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3068) Pkinase PF00069.20 KLO08214.1 - 1.7e-34 119.1 0.0 2.2e-34 118.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KLO08214.1 - 1e-32 113.2 0.0 1.4e-32 112.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KLO08214.1 - 2.1e-06 26.9 0.0 3e-06 26.3 0.0 1.1 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 KLO08214.1 - 0.00072 19.3 0.1 0.0016 18.2 0.0 1.5 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.9 KLO08214.1 - 0.023 13.7 0.0 0.045 12.8 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.6 KLO08214.1 - 0.072 11.9 0.0 0.11 11.3 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 EcKinase PF02958.15 KLO08214.1 - 0.079 12.0 0.0 0.13 11.3 0.0 1.2 1 0 0 1 1 1 0 Ecdysteroid kinase Oxidored_molyb PF00174.14 KLO08215.1 - 4.8e-46 156.2 0.0 7.9e-46 155.5 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain Mo-co_dimer PF03404.11 KLO08215.1 - 1.8e-21 76.1 1.5 3e-21 75.4 1.0 1.3 1 0 0 1 1 1 1 Mo-co oxidoreductase dimerisation domain Pkinase PF00069.20 KLO08218.1 - 8.7e-32 110.2 0.0 2.4e-29 102.2 0.0 2.0 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 KLO08218.1 - 5.6e-28 97.7 0.0 2.9e-26 92.1 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 KLO08218.1 - 0.00027 19.9 0.0 0.00041 19.4 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.6 KLO08218.1 - 0.0087 14.9 0.0 0.014 14.2 0.0 1.3 1 0 0 1 1 1 1 Seadornavirus VP7 APH PF01636.18 KLO08218.1 - 0.074 12.7 0.3 0.18 11.5 0.0 1.7 2 0 0 2 2 2 0 Phosphotransferase enzyme family Mo-co_dimer PF03404.11 KLO08219.1 - 1.8e-16 59.9 0.9 2.9e-16 59.2 0.2 1.7 2 0 0 2 2 2 1 Mo-co oxidoreductase dimerisation domain Oxidored_molyb PF00174.14 KLO08219.1 - 6.3e-16 58.2 0.0 3.5e-15 55.8 0.0 2.0 1 1 1 2 2 2 1 Oxidoreductase molybdopterin binding domain Pkinase PF00069.20 KLO08220.1 - 7.7e-23 80.9 0.0 9.3e-23 80.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KLO08220.1 - 2.6e-19 69.3 0.0 3.4e-19 68.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.17 KLO08220.1 - 0.0077 15.6 0.0 0.01 15.1 0.0 1.2 1 0 0 1 1 1 1 RIO1 family Cation_efflux PF01545.16 KLO08221.1 - 1.2e-46 159.0 13.4 2.7e-42 144.8 7.6 2.3 1 1 1 2 2 2 2 Cation efflux family GCIP PF13324.1 KLO08221.1 - 2.7 7.1 7.1 0.23 10.6 0.5 2.1 2 0 0 2 2 2 0 Grap2 and cyclin-D-interacting Cation_efflux PF01545.16 KLO08223.1 - 0.0024 17.0 0.1 0.0026 16.9 0.1 1.1 1 0 0 1 1 1 1 Cation efflux family F-box-like PF12937.2 KLO08224.1 - 2.8e-05 23.7 1.5 0.0029 17.3 0.0 2.7 2 0 0 2 2 2 2 F-box-like Pkinase PF00069.20 KLO08225.1 - 6.1e-41 140.2 0.0 8.3e-41 139.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KLO08225.1 - 6.6e-36 123.7 0.0 8.3e-36 123.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Zn_clus PF00172.13 KLO08225.1 - 0.00013 21.8 11.3 0.00022 21.0 7.8 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Kinase-like PF14531.1 KLO08225.1 - 0.00063 18.7 0.0 0.0011 18.0 0.0 1.3 1 0 0 1 1 1 1 Kinase-like DUF309 PF03745.9 KLO08225.1 - 0.048 13.1 0.6 0.13 11.7 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF309) F-box-like PF12937.2 KLO08226.1 - 5.4e-08 32.4 0.2 2.8e-07 30.1 0.0 2.3 2 0 0 2 2 2 1 F-box-like F-box-like PF12937.2 KLO08227.1 - 0.00011 21.7 0.9 0.00053 19.6 0.0 2.5 3 0 0 3 3 3 1 F-box-like p450 PF00067.17 KLO08228.1 - 1.4e-66 224.9 0.0 2e-66 224.4 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 FAD_binding_1 PF00667.15 KLO08228.1 - 5.1e-32 111.1 0.0 8.5e-32 110.3 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.20 KLO08228.1 - 5.2e-22 78.3 0.0 1.1e-21 77.3 0.0 1.5 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.16 KLO08228.1 - 4.2e-12 46.6 0.0 1.3e-11 45.0 0.0 1.9 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Flavodoxin_NdrI PF07972.6 KLO08228.1 - 0.05 13.5 0.0 0.19 11.6 0.0 2.0 2 0 0 2 2 2 0 NrdI Flavodoxin like adh_short_C2 PF13561.1 KLO08229.1 - 5.4e-18 65.6 0.0 6.3e-18 65.4 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 KLO08229.1 - 7.3e-13 48.7 1.6 1e-12 48.3 1.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KLO08229.1 - 0.0035 17.0 1.7 0.0046 16.6 0.9 1.5 1 1 0 1 1 1 1 KR domain F-box-like PF12937.2 KLO08230.1 - 4.8e-06 26.1 0.1 1.1e-05 25.0 0.1 1.6 1 0 0 1 1 1 1 F-box-like adh_short_C2 PF13561.1 KLO08231.1 - 1.2e-24 87.3 0.0 1.4e-24 87.2 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 KLO08231.1 - 5.8e-11 42.5 0.1 1e-10 41.7 0.1 1.4 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KLO08231.1 - 0.0018 17.9 0.0 0.0031 17.2 0.0 1.4 1 0 0 1 1 1 1 KR domain Eno-Rase_NADH_b PF12242.3 KLO08231.1 - 0.033 13.9 0.3 0.081 12.7 0.2 1.7 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Polysacc_synt_2 PF02719.10 KLO08231.1 - 0.055 12.3 0.2 0.08 11.8 0.2 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein THF_DHG_CYH_C PF02882.14 KLO08231.1 - 0.08 12.0 0.3 0.13 11.3 0.2 1.4 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain PRANC PF09372.5 KLO08231.1 - 0.1 12.5 0.0 0.21 11.5 0.0 1.4 1 0 0 1 1 1 0 PRANC domain NAD_binding_7 PF13241.1 KLO08231.1 - 0.11 12.7 0.8 0.65 10.2 0.2 2.1 2 0 0 2 2 2 0 Putative NAD(P)-binding NAD_binding_10 PF13460.1 KLO08231.1 - 0.11 12.5 0.7 0.36 10.8 0.5 2.0 1 1 0 1 1 1 0 NADH(P)-binding adh_short_C2 PF13561.1 KLO08232.1 - 9.2e-23 81.2 0.0 1.1e-22 81.0 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 KLO08232.1 - 6.1e-13 49.0 0.5 7.8e-13 48.6 0.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KLO08232.1 - 0.00029 20.5 0.1 0.00039 20.1 0.1 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 KLO08232.1 - 0.00087 19.3 3.5 0.013 15.5 2.4 2.2 1 1 0 1 1 1 1 NADH(P)-binding Saccharop_dh PF03435.13 KLO08232.1 - 0.011 14.7 0.5 0.014 14.3 0.3 1.1 1 0 0 1 1 1 0 Saccharopine dehydrogenase NAD_binding_7 PF13241.1 KLO08232.1 - 0.013 15.7 1.0 0.035 14.3 0.3 1.9 2 0 0 2 2 2 0 Putative NAD(P)-binding QRPTase_C PF01729.14 KLO08232.1 - 0.041 13.4 0.0 0.065 12.7 0.0 1.2 1 0 0 1 1 1 0 Quinolinate phosphoribosyl transferase, C-terminal domain Polysacc_synt_2 PF02719.10 KLO08232.1 - 0.051 12.4 0.1 0.074 11.9 0.1 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein PK_C PF02887.11 KLO08232.1 - 0.17 11.4 1.1 11 5.5 0.1 2.4 2 1 0 2 2 2 0 Pyruvate kinase, alpha/beta domain adh_short_C2 PF13561.1 KLO08233.1 - 1.8e-21 77.0 0.0 2.1e-21 76.8 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 KLO08233.1 - 2.1e-11 44.0 0.9 2.6e-11 43.7 0.6 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KLO08233.1 - 1.3e-06 28.1 0.2 2.3e-06 27.4 0.2 1.3 1 0 0 1 1 1 1 KR domain Eno-Rase_NADH_b PF12242.3 KLO08233.1 - 0.011 15.5 0.2 0.043 13.5 0.1 2.0 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase NAD_binding_7 PF13241.1 KLO08233.1 - 0.054 13.7 0.1 0.12 12.6 0.1 1.6 1 0 0 1 1 1 0 Putative NAD(P)-binding ATP-grasp_5 PF13549.1 KLO08233.1 - 0.074 12.2 0.1 0.12 11.5 0.1 1.3 1 0 0 1 1 1 0 ATP-grasp domain Glyco_hydro_3 PF00933.16 KLO08234.1 - 3.7e-66 223.1 0.0 5e-66 222.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 KLO08234.1 - 8.7e-52 175.8 0.1 1.4e-51 175.2 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 KLO08234.1 - 6.9e-21 73.9 0.1 1.8e-20 72.6 0.0 1.8 1 0 0 1 1 1 1 Fibronectin type III-like domain CARDB PF07705.6 KLO08234.1 - 0.056 13.5 6.7 0.031 14.3 1.7 2.6 2 1 1 3 3 3 0 CARDB Transglut_C PF00927.17 KLO08234.1 - 0.07 13.1 0.3 0.77 9.8 0.1 2.3 2 0 0 2 2 2 0 Transglutaminase family, C-terminal ig like domain DUF1034 PF06280.7 KLO08234.1 - 0.079 13.3 3.9 1.1 9.7 1.5 3.1 2 1 1 3 3 3 0 Fn3-like domain (DUF1034) Herpeto_peptide PF14409.1 KLO08235.1 - 0.015 15.0 0.0 0.062 13.0 0.0 2.0 2 0 0 2 2 2 0 Ribosomally synthesized peptide in Herpetosiphon F-box-like PF12937.2 KLO08235.1 - 0.039 13.6 1.5 0.093 12.4 1.0 1.6 1 0 0 1 1 1 0 F-box-like LRR_4 PF12799.2 KLO08235.1 - 1.4 8.6 13.0 0.25 11.0 0.6 3.9 4 1 0 4 4 4 0 Leucine Rich repeats (2 copies) LRR_7 PF13504.1 KLO08235.1 - 1.6 9.2 6.8 74 4.2 0.3 5.2 5 0 0 5 5 5 0 Leucine rich repeat NIF3 PF01784.13 KLO08236.1 - 2.2e-48 164.9 0.0 2.7e-48 164.6 0.0 1.0 1 0 0 1 1 1 1 NIF3 (NGG1p interacting factor 3) Podoplanin PF05808.6 KLO08237.1 - 0.028 13.9 0.1 0.042 13.3 0.1 1.3 1 0 0 1 1 1 0 Podoplanin Tir_receptor_M PF03549.9 KLO08237.1 - 0.071 13.2 1.1 0.071 13.2 0.8 1.9 2 0 0 2 2 2 0 Translocated intimin receptor (Tir) intimin-binding domain DDE_1 PF03184.14 KLO08238.1 - 1.8e-32 112.2 0.0 3.4e-32 111.3 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_3 PF13358.1 KLO08238.1 - 5.1e-07 29.5 0.0 8.5e-07 28.8 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease RNA_pol_L_2 PF13656.1 KLO08239.1 - 8.1e-11 41.2 0.0 1.1e-10 40.7 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.19 KLO08239.1 - 0.00065 18.7 0.0 0.00088 18.3 0.0 1.3 1 1 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Ion_trans PF00520.26 KLO08240.1 - 2.3e-17 62.8 15.8 3.5e-17 62.3 10.9 1.2 1 0 0 1 1 1 1 Ion transport protein Ion_trans_2 PF07885.11 KLO08240.1 - 1.1e-12 47.4 3.4 1.1e-12 47.4 2.3 2.8 3 0 0 3 3 3 1 Ion channel DUF3713 PF12506.3 KLO08241.1 - 3.4 7.7 7.3 10 6.2 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3713) TPR_7 PF13176.1 KLO08242.1 - 0.19 11.6 0.6 1.7 8.6 0.1 2.3 1 1 1 2 2 2 0 Tetratricopeptide repeat DDE_1 PF03184.14 KLO08249.1 - 5.1e-15 55.2 0.0 7.7e-15 54.6 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_3 PF13358.1 KLO08249.1 - 0.0011 18.7 0.0 0.0018 18.0 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease Methyltransf_32 PF13679.1 KLO08249.1 - 0.11 12.2 0.1 0.18 11.4 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain DUF4549 PF15082.1 KLO08254.1 - 0.039 13.5 0.3 0.06 12.9 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4549) EF-hand_1 PF00036.27 KLO08262.1 - 1.1e-23 80.6 13.8 1.9e-05 23.6 0.6 4.2 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.1 KLO08262.1 - 7.1e-22 77.3 5.4 2e-10 40.6 1.6 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.1 KLO08262.1 - 6.6e-20 69.4 12.6 3.7e-05 22.8 0.4 4.3 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.1 KLO08262.1 - 5.7e-18 63.1 8.8 0.00036 20.1 0.0 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.1 KLO08262.1 - 2.7e-13 49.3 13.1 0.00015 21.2 3.3 4.5 3 1 1 4 4 4 3 EF-hand domain pair SPARC_Ca_bdg PF10591.4 KLO08262.1 - 8.4e-06 25.8 0.0 0.081 12.9 0.0 2.2 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.2 KLO08262.1 - 0.00012 21.7 7.1 0.026 14.2 0.9 3.7 1 1 3 4 4 4 1 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.1 KLO08262.1 - 0.065 13.1 0.1 1.7 8.6 0.0 2.8 3 0 0 3 3 3 0 EF-hand domain Pap_E4 PF02711.9 KLO08263.1 - 1.3 9.9 5.8 0.7 10.7 2.3 1.9 1 1 0 1 1 1 0 E4 protein KIAA1328 PF15369.1 KLO08263.1 - 1.7 8.3 7.9 2.1 8.0 5.5 1.2 1 0 0 1 1 1 0 Uncharacterised protein KIAA1328 ADH_zinc_N PF00107.21 KLO08265.1 - 2.1e-06 27.3 0.8 3.6e-06 26.5 0.5 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KLO08265.1 - 7.9e-06 25.6 0.0 1.9e-05 24.3 0.0 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain FAD_binding_4 PF01565.18 KLO08265.1 - 0.024 14.0 1.0 0.049 13.1 0.7 1.5 1 0 0 1 1 1 0 FAD binding domain DnaJ PF00226.26 KLO08266.1 - 5.3e-17 61.3 0.0 8.5e-17 60.6 0.0 1.3 1 0 0 1 1 1 1 DnaJ domain Gln-synt_C PF00120.19 KLO08267.1 - 2.9e-61 206.8 0.0 3.5e-61 206.6 0.0 1.1 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain Gln-synt_N PF03951.14 KLO08267.1 - 9.2e-17 60.4 0.0 1.5e-16 59.7 0.0 1.3 1 0 0 1 1 1 1 Glutamine synthetase, beta-Grasp domain SLS PF14611.1 KLO08267.1 - 0.17 11.2 0.0 0.29 10.5 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial inner-membrane-bound regulator HABP4_PAI-RBP1 PF04774.10 KLO08268.1 - 0.022 15.2 1.8 0.043 14.3 1.2 1.4 1 0 0 1 1 1 0 Hyaluronan / mRNA binding family TrmE_N PF10396.4 KLO08269.1 - 2.2e-34 117.8 0.0 4.8e-34 116.7 0.0 1.6 1 0 0 1 1 1 1 GTP-binding protein TrmE N-terminus MMR_HSR1 PF01926.18 KLO08269.1 - 1.4e-16 60.4 0.1 8.3e-16 57.9 0.0 2.3 2 0 0 2 2 2 1 50S ribosome-binding GTPase GTPase_Cys_C PF12631.2 KLO08269.1 - 3.3e-14 53.0 0.1 1e-13 51.4 0.0 1.9 1 0 0 1 1 1 1 Catalytic cysteine-containing C-terminus of GTPase, MnmE FeoB_N PF02421.13 KLO08269.1 - 4.6e-06 26.0 0.0 1e-05 24.8 0.0 1.6 2 0 0 2 2 2 1 Ferrous iron transport protein B Dynamin_N PF00350.18 KLO08269.1 - 0.018 14.8 0.0 0.058 13.1 0.0 1.8 2 0 0 2 2 2 0 Dynamin family DUF258 PF03193.11 KLO08269.1 - 0.029 13.5 0.1 0.075 12.2 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function, DUF258 Miro PF08477.8 KLO08269.1 - 0.084 13.3 0.0 0.21 12.0 0.0 1.7 1 0 0 1 1 1 0 Miro-like protein AIG1 PF04548.11 KLO08269.1 - 0.09 11.8 0.0 0.16 11.0 0.0 1.3 1 0 0 1 1 1 0 AIG1 family GN3L_Grn1 PF08701.6 KLO08270.1 - 2.2e-23 81.9 23.2 2.2e-23 81.9 16.1 2.7 2 1 0 2 2 1 1 GNL3L/Grn1 putative GTPase MMR_HSR1 PF01926.18 KLO08270.1 - 1.6e-11 44.1 0.4 3.9e-08 33.2 0.0 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase AIG1 PF04548.11 KLO08270.1 - 3.7e-07 29.4 0.0 3.7e-07 29.4 0.0 2.5 3 0 0 3 3 3 1 AIG1 family Dynamin_N PF00350.18 KLO08270.1 - 4.4e-05 23.3 0.0 4.4e-05 23.3 0.0 3.9 3 1 0 3 3 3 1 Dynamin family GTP_EFTU PF00009.22 KLO08270.1 - 6e-05 22.5 3.5 0.0047 16.3 0.0 3.2 3 1 0 3 3 3 2 Elongation factor Tu GTP binding domain Nop14 PF04147.7 KLO08270.1 - 8.8e-05 20.6 18.9 8.8e-05 20.6 13.1 2.8 2 1 0 2 2 1 1 Nop14-like family Miro PF08477.8 KLO08270.1 - 0.00023 21.6 0.2 0.063 13.7 0.0 3.2 3 0 0 3 3 3 1 Miro-like protein FeoB_N PF02421.13 KLO08270.1 - 0.0017 17.6 0.1 0.073 12.3 0.0 2.4 2 1 0 2 2 2 1 Ferrous iron transport protein B DUF258 PF03193.11 KLO08270.1 - 0.0057 15.8 0.2 0.02 14.0 0.1 1.8 1 1 0 2 2 2 1 Protein of unknown function, DUF258 Septin PF00735.13 KLO08270.1 - 0.019 13.9 0.0 0.053 12.5 0.0 1.7 1 0 0 1 1 1 0 Septin GBP PF02263.14 KLO08270.1 - 0.033 13.2 0.0 0.066 12.2 0.0 1.4 1 0 0 1 1 1 0 Guanylate-binding protein, N-terminal domain DUF2361 PF10153.4 KLO08271.1 - 5.8e-32 110.2 7.9 5.8e-32 110.2 5.5 2.2 3 0 0 3 3 3 1 Uncharacterised conserved protein (DUF2361) Menin PF05053.8 KLO08271.1 - 0.034 12.3 2.4 0.051 11.7 1.7 1.3 1 0 0 1 1 1 0 Menin RNB PF00773.14 KLO08272.1 - 5.4e-99 331.5 0.3 1.1e-98 330.5 0.2 1.5 1 0 0 1 1 1 1 RNB domain Iso_dh PF00180.15 KLO08273.1 - 9.8e-100 333.8 0.0 1.2e-99 333.5 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Snf7 PF03357.16 KLO08275.1 - 1.4e-26 92.9 23.7 3e-26 91.8 16.4 1.5 1 1 0 1 1 1 1 Snf7 DUF826 PF05696.6 KLO08275.1 - 0.061 13.4 1.4 0.14 12.3 1.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF826) Vps51 PF08700.6 KLO08275.1 - 0.33 10.8 0.0 0.33 10.8 0.0 3.2 4 0 0 4 4 4 0 Vps51/Vps67 Plasmid_RAQPRD PF09686.5 KLO08275.1 - 1.1 9.4 6.0 3.4 7.8 0.4 2.6 2 0 0 2 2 2 0 Plasmid protein of unknown function (Plasmid_RAQPRD) DUF4140 PF13600.1 KLO08275.1 - 1.4 9.4 7.7 0.93 9.9 0.2 2.9 2 1 0 3 3 3 0 N-terminal domain of unknown function (DUF4140) GPI-anchored PF10342.4 KLO08276.1 - 4.9e-13 49.3 4.9 7.7e-13 48.7 3.4 1.3 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Med17 PF10156.4 KLO08277.1 - 7.4e-46 156.3 0.0 1e-45 155.9 0.0 1.1 1 0 0 1 1 1 1 Subunit 17 of Mediator complex Fungal_trans PF04082.13 KLO08278.1 - 1.2e-16 60.3 0.1 2e-16 59.6 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KLO08278.1 - 3e-05 23.8 9.9 4.9e-05 23.1 6.9 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fibrinogen_BP PF08017.6 KLO08278.1 - 0.027 12.6 0.1 0.046 11.9 0.0 1.3 1 0 0 1 1 1 0 Fibrinogen binding protein VID27 PF08553.5 KLO08280.1 - 1.5e-235 784.1 0.9 1.9e-235 783.8 0.6 1.1 1 0 0 1 1 1 1 VID27 cytoplasmic protein DUF3605 PF12239.3 KLO08281.1 - 2.5e-28 98.9 0.1 1.3e-19 70.5 0.0 3.0 2 1 0 2 2 2 2 Protein of unknown function (DUF3605) Clat_adaptor_s PF01217.15 KLO08283.1 - 6.7e-56 187.9 1.6 7.8e-56 187.7 1.1 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain DUF1204 PF06721.6 KLO08283.1 - 0.05 12.8 0.1 0.091 11.9 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1204) RNase_T PF00929.19 KLO08284.1 - 1.9e-15 57.5 0.0 3.2e-15 56.7 0.0 1.4 1 0 0 1 1 1 1 Exonuclease Zn_clus PF00172.13 KLO08284.1 - 0.00021 21.1 6.9 0.00021 21.1 4.8 2.3 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain YxiJ PF14176.1 KLO08284.1 - 0.068 13.2 0.0 0.13 12.3 0.0 1.4 1 0 0 1 1 1 0 YxiJ-like protein NifT PF06988.6 KLO08284.1 - 0.2 11.1 0.0 0.55 9.7 0.0 1.7 1 0 0 1 1 1 0 NifT/FixU protein CHORD PF04968.7 KLO08284.1 - 0.23 11.7 8.4 0.029 14.6 2.8 1.9 2 0 0 2 2 2 0 CHORD TRAM_LAG1_CLN8 PF03798.11 KLO08285.1 - 3.4e-32 111.6 26.5 3.4e-32 111.6 18.4 1.5 2 0 0 2 2 2 1 TLC domain TRAM1 PF08390.6 KLO08285.1 - 1.4e-11 43.6 0.0 1.4e-11 43.6 0.0 1.9 2 0 0 2 2 2 1 TRAM1-like protein F-box-like PF12937.2 KLO08286.1 - 6.2e-08 32.2 0.3 1.4e-07 31.0 0.2 1.7 1 0 0 1 1 1 1 F-box-like F-box-like_2 PF13013.1 KLO08286.1 - 0.00063 19.4 0.3 0.029 14.1 0.2 2.5 1 1 0 1 1 1 1 F-box-like domain F-box PF00646.28 KLO08286.1 - 0.0011 18.6 0.0 0.0038 16.8 0.0 1.9 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 KLO08287.1 - 9.4e-06 25.2 0.0 2.7e-05 23.7 0.0 1.8 1 0 0 1 1 1 1 F-box-like F-box-like PF12937.2 KLO08288.1 - 3.3e-07 29.9 0.0 6.8e-07 28.9 0.0 1.6 1 0 0 1 1 1 1 F-box-like F-box-like PF12937.2 KLO08289.1 - 0.00014 21.5 0.0 0.00036 20.1 0.0 1.8 1 0 0 1 1 1 1 F-box-like zf-HYPF PF07503.7 KLO08290.1 - 0.014 14.7 0.0 0.063 12.6 0.0 2.0 2 0 0 2 2 2 0 HypF finger WAK PF08488.6 KLO08290.1 - 0.037 14.3 0.0 0.15 12.3 0.0 1.9 2 0 0 2 2 2 0 Wall-associated kinase BAAT_C PF08840.6 KLO08290.1 - 0.055 13.1 0.0 0.069 12.8 0.0 1.2 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal F-box-like PF12937.2 KLO08291.1 - 1.2e-05 24.9 0.0 3.6e-05 23.3 0.0 1.9 1 0 0 1 1 1 1 F-box-like F-box-like PF12937.2 KLO08292.1 - 1.5e-06 27.7 0.0 4.4e-06 26.3 0.0 1.9 1 0 0 1 1 1 1 F-box-like Lpp-LpqN PF10738.4 KLO08292.1 - 0.19 10.9 0.0 0.37 10.0 0.0 1.4 1 0 0 1 1 1 0 Probable lipoprotein LpqN F-box-like PF12937.2 KLO08293.1 - 9e-06 25.3 0.0 2.8e-05 23.7 0.0 1.9 1 0 0 1 1 1 1 F-box-like FAM180 PF15173.1 KLO08293.1 - 0.059 13.1 0.1 0.52 10.0 0.1 2.3 2 0 0 2 2 2 0 FAM180 family F-box-like PF12937.2 KLO08294.1 - 1.3e-06 28.0 0.0 3e-06 26.8 0.0 1.6 1 0 0 1 1 1 1 F-box-like F-box-like PF12937.2 KLO08295.1 - 4.6e-07 29.4 0.0 1.3e-06 28.0 0.0 1.8 1 0 0 1 1 1 1 F-box-like F-box-like PF12937.2 KLO08296.1 - 5.7e-07 29.1 0.1 2e-06 27.4 0.1 2.0 1 0 0 1 1 1 1 F-box-like F-box-like PF12937.2 KLO08297.1 - 2.1e-07 30.5 0.2 7.2e-07 28.8 0.0 2.1 2 0 0 2 2 2 1 F-box-like LRR_7 PF13504.1 KLO08297.1 - 0.6 10.5 6.2 16 6.2 0.1 5.0 5 1 1 6 6 6 0 Leucine rich repeat F-box-like PF12937.2 KLO08299.1 - 4.8e-10 39.0 0.1 1.2e-09 37.7 0.1 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KLO08299.1 - 0.0059 16.2 0.1 0.51 10.0 0.0 2.7 2 0 0 2 2 2 1 F-box domain F-box-like_2 PF13013.1 KLO08299.1 - 0.081 12.6 4.1 2.5 7.8 0.4 3.8 3 1 0 3 3 3 0 F-box-like domain F-box-like PF12937.2 KLO08300.1 - 4.6e-08 32.6 0.1 1.3e-06 27.9 0.0 2.8 2 0 0 2 2 2 1 F-box-like F-box-like PF12937.2 KLO08301.1 - 1.3e-07 31.1 0.0 3.5e-07 29.8 0.0 1.8 1 0 0 1 1 1 1 F-box-like F-box-like PF12937.2 KLO08302.1 - 8.3e-08 31.8 0.0 2.2e-07 30.5 0.0 1.8 1 0 0 1 1 1 1 F-box-like F-box-like PF12937.2 KLO08303.1 - 4.5e-09 35.8 0.5 2.6e-06 27.0 0.0 3.4 3 0 0 3 3 3 2 F-box-like F-box-like PF12937.2 KLO08304.1 - 1.3e-05 24.8 0.1 4e-05 23.2 0.1 1.9 1 0 0 1 1 1 1 F-box-like F-box-like PF12937.2 KLO08305.1 - 9.7e-07 28.4 0.0 2e-06 27.4 0.0 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KLO08305.1 - 0.013 15.1 0.0 0.043 13.4 0.0 2.0 1 1 0 1 1 1 0 F-box domain F-box-like PF12937.2 KLO08307.1 - 0.00026 20.6 0.1 0.00051 19.7 0.0 1.5 1 0 0 1 1 1 1 F-box-like F-box-like PF12937.2 KLO08308.1 - 6.5e-08 32.1 0.0 1.7e-07 30.8 0.0 1.8 1 0 0 1 1 1 1 F-box-like F-box-like PF12937.2 KLO08309.1 - 3.3e-09 36.3 0.1 3.2e-08 33.1 0.0 2.4 2 0 0 2 2 2 1 F-box-like F-box-like PF12937.2 KLO08310.1 - 3.3e-07 29.9 0.2 1.6e-06 27.7 0.0 2.4 2 0 0 2 2 2 1 F-box-like F-box-like PF12937.2 KLO08312.1 - 2.9e-07 30.1 0.0 1.2e-06 28.1 0.0 2.0 1 0 0 1 1 1 1 F-box-like F-box-like PF12937.2 KLO08313.1 - 5.1e-07 29.3 0.1 1.4e-06 27.9 0.1 1.7 1 0 0 1 1 1 1 F-box-like WD40 PF00400.27 KLO08314.1 - 2.5e-53 176.1 23.5 3e-13 49.0 0.1 7.7 7 0 0 7 7 7 7 WD domain, G-beta repeat NACHT PF05729.7 KLO08314.1 - 1.5e-12 47.5 0.0 0.00012 21.7 0.0 3.5 2 2 0 2 2 2 2 NACHT domain AAA_16 PF13191.1 KLO08314.1 - 5.2e-12 46.1 0.1 3.1e-05 24.0 0.0 3.6 3 0 0 3 3 3 2 AAA ATPase domain AAA_22 PF13401.1 KLO08314.1 - 7.2e-08 32.6 0.0 0.0045 17.1 0.0 3.1 2 0 0 2 2 2 2 AAA domain NB-ARC PF00931.17 KLO08314.1 - 1.8e-07 30.3 0.0 9.2e-05 21.4 0.0 2.8 2 1 0 2 2 2 1 NB-ARC domain AAA PF00004.24 KLO08314.1 - 2.1e-07 31.1 0.0 0.01 16.0 0.0 3.4 2 1 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) Zeta_toxin PF06414.7 KLO08314.1 - 7.2e-07 28.5 0.0 0.023 13.8 0.0 2.4 2 0 0 2 2 2 2 Zeta toxin AAA_17 PF13207.1 KLO08314.1 - 2.1e-06 28.5 0.8 0.063 14.1 0.0 3.8 3 0 0 3 3 2 2 AAA domain AAA_18 PF13238.1 KLO08314.1 - 2.2e-06 27.9 0.0 0.044 14.0 0.0 3.4 2 1 0 2 2 2 2 AAA domain AAA_25 PF13481.1 KLO08314.1 - 6.3e-06 25.7 0.0 0.0091 15.4 0.0 3.1 3 0 0 3 3 2 1 AAA domain APS_kinase PF01583.15 KLO08314.1 - 1e-05 25.2 0.0 0.072 12.7 0.0 2.5 2 0 0 2 2 2 2 Adenylylsulphate kinase RNA_helicase PF00910.17 KLO08314.1 - 1.2e-05 25.4 0.0 0.24 11.5 0.0 3.0 3 0 0 3 3 2 2 RNA helicase DUF2075 PF09848.4 KLO08314.1 - 0.00011 21.2 0.0 0.15 11.0 0.0 2.3 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2075) AAA_19 PF13245.1 KLO08314.1 - 0.00031 20.4 0.0 0.79 9.5 0.0 2.6 2 0 0 2 2 2 2 Part of AAA domain AAA_33 PF13671.1 KLO08314.1 - 0.00072 19.4 0.0 0.46 10.3 0.0 2.7 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.12 KLO08314.1 - 0.001 18.5 0.0 0.79 9.1 0.0 2.9 3 0 0 3 3 3 1 IstB-like ATP binding protein ABC_tran PF00005.22 KLO08314.1 - 0.0012 19.1 0.0 0.2 11.9 0.0 2.7 2 0 0 2 2 2 1 ABC transporter AAA_14 PF13173.1 KLO08314.1 - 0.0013 18.6 0.0 0.61 9.9 0.0 3.6 2 1 0 2 2 2 1 AAA domain Parvo_NS1 PF01057.12 KLO08314.1 - 0.0016 17.3 1.6 0.075 11.8 0.1 2.9 3 0 0 3 3 3 1 Parvovirus non-structural protein NS1 PPV_E1_C PF00519.12 KLO08314.1 - 0.0016 17.1 0.0 1.1 7.7 0.0 2.3 2 0 0 2 2 2 2 Papillomavirus helicase KAP_NTPase PF07693.9 KLO08314.1 - 0.0018 17.3 6.5 0.66 8.9 0.1 4.0 4 1 0 5 5 5 2 KAP family P-loop domain Viral_helicase1 PF01443.13 KLO08314.1 - 0.0024 17.4 0.0 2.1 7.8 0.0 2.4 2 0 0 2 2 2 2 Viral (Superfamily 1) RNA helicase Arch_ATPase PF01637.13 KLO08314.1 - 0.0035 17.0 0.0 0.037 13.7 0.0 2.5 2 0 0 2 2 2 1 Archaeal ATPase TrwB_AAD_bind PF10412.4 KLO08314.1 - 0.0079 14.8 0.0 1.3 7.5 0.0 2.9 3 0 0 3 3 3 1 Type IV secretion-system coupling protein DNA-binding domain AAA_11 PF13086.1 KLO08314.1 - 0.0095 15.5 0.0 0.78 9.2 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.1 KLO08314.1 - 0.0097 15.4 0.0 2.1 7.9 0.0 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_28 PF13521.1 KLO08314.1 - 0.0099 15.8 0.0 1.6 8.6 0.0 2.6 2 0 0 2 2 2 1 AAA domain FtsK_SpoIIIE PF01580.13 KLO08314.1 - 0.0099 15.3 0.0 8.7 5.7 0.0 3.1 3 0 0 3 3 3 0 FtsK/SpoIIIE family Nbas_N PF15492.1 KLO08314.1 - 0.015 14.4 0.5 0.32 10.0 0.0 2.9 3 1 0 3 3 3 0 Neuroblastoma-amplified sequence, N terminal AAA_30 PF13604.1 KLO08314.1 - 0.015 14.8 0.0 0.56 9.7 0.0 2.4 2 0 0 2 2 2 0 AAA domain ResIII PF04851.10 KLO08314.1 - 0.016 15.0 0.0 0.46 10.2 0.0 2.3 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit ArgK PF03308.11 KLO08314.1 - 0.016 13.9 0.0 1.4 7.6 0.0 2.6 3 0 0 3 3 2 0 ArgK protein TIP49 PF06068.8 KLO08314.1 - 0.02 13.6 0.0 0.91 8.1 0.0 2.2 2 0 0 2 2 2 0 TIP49 C-terminus AAA_23 PF13476.1 KLO08314.1 - 0.022 15.0 0.5 0.87 9.8 0.0 2.8 3 0 0 3 3 2 0 AAA domain MobB PF03205.9 KLO08314.1 - 0.023 14.3 0.0 0.13 11.9 0.0 2.2 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_24 PF13479.1 KLO08314.1 - 0.037 13.6 0.6 1 8.8 0.2 2.6 2 0 0 2 2 2 0 AAA domain Mg_chelatase PF01078.16 KLO08314.1 - 0.04 13.0 0.0 5.2 6.1 0.0 2.4 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_PrkA PF08298.6 KLO08314.1 - 0.056 12.1 0.0 0.81 8.3 0.0 2.1 2 0 0 2 2 2 0 PrkA AAA domain AAA_5 PF07728.9 KLO08314.1 - 0.058 13.1 0.0 1.7 8.3 0.0 2.6 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) KTI12 PF08433.5 KLO08314.1 - 0.074 12.2 0.0 2 7.5 0.0 2.6 3 0 0 3 3 2 0 Chromatin associated protein KTI12 cobW PF02492.14 KLO08314.1 - 0.082 12.3 0.0 2 7.8 0.0 2.6 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain NTPase_1 PF03266.10 KLO08314.1 - 0.083 12.5 0.0 1.3 8.7 0.0 2.4 2 0 0 2 2 2 0 NTPase Torsin PF06309.6 KLO08314.1 - 0.096 12.5 0.0 14 5.5 0.0 2.6 2 0 0 2 2 2 0 Torsin AAA_10 PF12846.2 KLO08314.1 - 0.12 11.8 1.1 8.6 5.7 0.0 3.0 3 1 0 3 3 2 0 AAA-like domain ADK PF00406.17 KLO08314.1 - 0.14 12.0 0.5 3.4 7.5 0.0 2.8 3 0 0 3 3 2 0 Adenylate kinase ATP-synt_ab PF00006.20 KLO08314.1 - 0.18 11.3 0.0 5.3 6.4 0.0 2.3 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain zf-C2H2_4 PF13894.1 KLO08316.1 - 1.4e-06 28.2 9.2 0.16 12.3 0.3 3.6 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2 PF00096.21 KLO08316.1 - 5.9e-06 26.3 8.9 0.02 15.2 0.2 3.6 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-met PF12874.2 KLO08316.1 - 0.016 15.3 0.3 0.53 10.5 0.1 2.6 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-H2C2_2 PF13465.1 KLO08316.1 - 0.048 13.9 10.8 0.27 11.6 0.4 3.8 4 0 0 4 4 4 0 Zinc-finger double domain zf-H2C2_5 PF13909.1 KLO08316.1 - 0.055 13.7 7.1 1.8 8.9 0.3 3.6 3 0 0 3 3 3 0 C2H2-type zinc-finger domain IBR PF01485.16 KLO08316.1 - 0.59 10.0 4.5 1.4 8.7 0.4 2.3 2 0 0 2 2 2 0 IBR domain WD40 PF00400.27 KLO08317.1 - 1.7e-58 192.4 29.8 3.8e-13 48.7 0.5 7.9 7 0 0 7 7 7 6 WD domain, G-beta repeat AAA_22 PF13401.1 KLO08317.1 - 1.9e-12 47.4 0.0 9.7e-06 25.7 0.0 2.9 2 0 0 2 2 2 2 AAA domain NACHT PF05729.7 KLO08317.1 - 2.6e-10 40.2 0.1 4.5e-06 26.4 0.0 3.4 2 1 0 2 2 2 2 NACHT domain AAA_17 PF13207.1 KLO08317.1 - 3e-08 34.4 0.0 0.019 15.7 0.0 3.4 2 0 0 2 2 2 2 AAA domain NB-ARC PF00931.17 KLO08317.1 - 4.5e-08 32.3 0.2 8.7e-05 21.5 0.0 3.4 3 1 0 3 3 3 1 NB-ARC domain AAA PF00004.24 KLO08317.1 - 1.7e-07 31.5 0.0 0.017 15.3 0.0 3.0 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 KLO08317.1 - 2.4e-07 30.9 0.0 0.031 14.2 0.0 3.3 2 1 0 2 2 2 2 AAA ATPase domain APS_kinase PF01583.15 KLO08317.1 - 3.9e-07 29.8 0.0 0.043 13.4 0.0 3.3 3 0 0 3 3 3 2 Adenylylsulphate kinase Zeta_toxin PF06414.7 KLO08317.1 - 9.4e-07 28.1 0.0 0.042 12.9 0.0 2.4 2 0 0 2 2 2 2 Zeta toxin AAA_18 PF13238.1 KLO08317.1 - 4.7e-06 26.9 0.0 0.2 11.9 0.0 3.2 2 1 0 2 2 2 2 AAA domain RNA_helicase PF00910.17 KLO08317.1 - 7.2e-06 26.1 0.0 0.29 11.3 0.0 3.2 2 0 0 2 2 2 2 RNA helicase AAA_25 PF13481.1 KLO08317.1 - 7.4e-06 25.5 0.0 0.16 11.3 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_33 PF13671.1 KLO08317.1 - 1.3e-05 25.1 0.0 0.25 11.1 0.0 2.9 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.1 KLO08317.1 - 7.5e-05 22.4 0.0 0.037 13.7 0.0 2.8 2 0 0 2 2 2 1 Part of AAA domain AAA_28 PF13521.1 KLO08317.1 - 9.6e-05 22.3 0.0 0.6 10.0 0.0 2.9 2 0 0 2 2 2 2 AAA domain DUF2075 PF09848.4 KLO08317.1 - 0.00012 21.2 0.0 0.3 10.0 0.0 2.2 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2075) Nbas_N PF15492.1 KLO08317.1 - 0.00025 20.2 0.3 4.4 6.3 0.0 3.8 3 1 0 3 3 3 0 Neuroblastoma-amplified sequence, N terminal AAA_14 PF13173.1 KLO08317.1 - 0.00051 19.9 0.2 2.6 7.9 0.0 4.2 4 2 0 4 4 2 1 AAA domain PD40 PF07676.7 KLO08317.1 - 0.0015 18.1 0.2 35 4.1 0.0 4.8 5 0 0 5 5 4 0 WD40-like Beta Propeller Repeat ABC_tran PF00005.22 KLO08317.1 - 0.0017 18.6 0.0 0.61 10.3 0.0 2.7 2 0 0 2 2 2 1 ABC transporter Viral_helicase1 PF01443.13 KLO08317.1 - 0.0018 17.8 0.0 1.3 8.4 0.0 2.3 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase MobB PF03205.9 KLO08317.1 - 0.0018 17.9 0.1 0.0083 15.8 0.0 2.2 2 0 0 2 2 1 1 Molybdopterin guanine dinucleotide synthesis protein B IstB_IS21 PF01695.12 KLO08317.1 - 0.0047 16.3 0.0 3.3 7.0 0.0 2.4 2 0 0 2 2 2 0 IstB-like ATP binding protein Parvo_NS1 PF01057.12 KLO08317.1 - 0.01 14.7 0.1 2.6 6.8 0.0 2.3 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 AAA_30 PF13604.1 KLO08317.1 - 0.013 15.0 0.3 0.25 10.8 0.0 2.3 2 0 0 2 2 2 0 AAA domain RuvB_N PF05496.7 KLO08317.1 - 0.014 14.4 0.0 1.3 8.0 0.0 2.4 2 0 0 2 2 2 0 Holliday junction DNA helicase ruvB N-terminus ArgK PF03308.11 KLO08317.1 - 0.015 14.0 0.0 0.93 8.2 0.0 2.3 2 0 0 2 2 2 0 ArgK protein Torsin PF06309.6 KLO08317.1 - 0.017 15.0 0.0 7.1 6.5 0.0 2.6 2 0 0 2 2 2 0 Torsin eIF2A PF08662.6 KLO08317.1 - 0.025 14.3 0.0 0.073 12.7 0.0 1.7 2 0 0 2 2 1 0 Eukaryotic translation initiation factor eIF2A NTPase_1 PF03266.10 KLO08317.1 - 0.026 14.2 0.0 0.6 9.8 0.0 2.5 2 0 0 2 2 2 0 NTPase Rad17 PF03215.10 KLO08317.1 - 0.029 13.0 0.1 4.3 5.8 0.0 2.2 2 0 0 2 2 2 0 Rad17 cell cycle checkpoint protein AAA_5 PF07728.9 KLO08317.1 - 0.04 13.6 0.0 5.2 6.7 0.0 2.7 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) ResIII PF04851.10 KLO08317.1 - 0.049 13.4 0.0 0.45 10.3 0.0 2.2 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit AAA_11 PF13086.1 KLO08317.1 - 0.056 13.0 0.0 2.6 7.5 0.0 2.6 2 0 0 2 2 2 0 AAA domain TIP49 PF06068.8 KLO08317.1 - 0.059 12.0 0.0 6.2 5.4 0.0 2.2 2 0 0 2 2 2 0 TIP49 C-terminus TrwB_AAD_bind PF10412.4 KLO08317.1 - 0.07 11.7 0.0 1 7.9 0.0 2.3 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain FtsK_SpoIIIE PF01580.13 KLO08317.1 - 0.073 12.5 0.0 15 4.9 0.0 2.9 2 0 0 2 2 2 0 FtsK/SpoIIIE family KTI12 PF08433.5 KLO08317.1 - 0.077 12.1 0.0 4.7 6.3 0.0 2.3 2 0 0 2 2 2 0 Chromatin associated protein KTI12 AAA_10 PF12846.2 KLO08317.1 - 0.09 12.1 0.5 3.8 6.8 0.0 3.0 3 0 0 3 3 3 0 AAA-like domain Peptidase_S9_N PF02897.10 KLO08317.1 - 0.091 11.3 0.0 0.17 10.4 0.0 1.4 1 0 0 1 1 1 0 Prolyl oligopeptidase, N-terminal beta-propeller domain AAA_29 PF13555.1 KLO08317.1 - 0.1 12.1 0.1 15 5.2 0.0 2.6 2 0 0 2 2 2 0 P-loop containing region of AAA domain KaiC PF06745.8 KLO08317.1 - 0.12 11.5 0.0 2.2 7.3 0.0 2.5 2 0 0 2 2 2 0 KaiC AAA_24 PF13479.1 KLO08317.1 - 0.12 11.9 0.7 4.8 6.7 0.1 2.6 2 0 0 2 2 2 0 AAA domain SRP54 PF00448.17 KLO08317.1 - 0.12 11.8 0.4 0.6 9.5 0.0 2.3 3 0 0 3 3 3 0 SRP54-type protein, GTPase domain UPF0079 PF02367.12 KLO08317.1 - 0.13 11.8 0.0 2.6 7.7 0.0 2.4 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 ADK PF00406.17 KLO08317.1 - 0.13 12.1 0.9 5.3 6.9 0.1 2.7 2 0 0 2 2 2 0 Adenylate kinase Mg_chelatase PF01078.16 KLO08317.1 - 0.14 11.3 0.1 14 4.7 0.0 2.4 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI PhoH PF02562.11 KLO08317.1 - 0.19 10.9 0.0 8.7 5.5 0.0 2.5 2 0 0 2 2 2 0 PhoH-like protein Nucleoporin_N PF08801.6 KLO08317.1 - 0.38 9.4 3.4 0.53 8.9 0.4 2.1 1 1 1 2 2 2 0 Nup133 N terminal like NOZZLE PF08744.5 KLO08318.1 - 0.025 13.9 0.1 0.031 13.6 0.1 1.1 1 0 0 1 1 1 0 Plant transcription factor NOZZLE WD40 PF00400.27 KLO08319.1 - 1.6e-57 189.4 33.6 4.7e-11 42.1 0.4 7.9 8 0 0 8 8 7 7 WD domain, G-beta repeat AAA_16 PF13191.1 KLO08319.1 - 7.3e-11 42.3 0.2 0.00042 20.3 0.0 4.3 3 1 0 3 3 2 2 AAA ATPase domain NACHT PF05729.7 KLO08319.1 - 8.7e-11 41.7 1.6 0.00019 21.1 0.0 4.0 2 2 0 2 2 2 2 NACHT domain AAA_22 PF13401.1 KLO08319.1 - 8.5e-09 35.6 0.0 0.00054 20.1 0.0 3.8 3 0 0 3 3 3 2 AAA domain AAA PF00004.24 KLO08319.1 - 1e-08 35.4 0.0 0.0046 17.1 0.0 3.7 2 1 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) NB-ARC PF00931.17 KLO08319.1 - 6.6e-08 31.7 0.0 4.3e-06 25.7 0.0 2.9 3 0 0 3 3 3 1 NB-ARC domain Zeta_toxin PF06414.7 KLO08319.1 - 2.5e-06 26.7 0.0 0.0055 15.8 0.0 2.5 2 0 0 2 2 2 2 Zeta toxin RNA_helicase PF00910.17 KLO08319.1 - 4.4e-06 26.8 0.0 0.11 12.6 0.0 3.5 3 0 0 3 3 3 2 RNA helicase AAA_19 PF13245.1 KLO08319.1 - 4.6e-06 26.2 0.0 0.023 14.4 0.0 2.8 2 0 0 2 2 2 2 Part of AAA domain AAA_33 PF13671.1 KLO08319.1 - 4.7e-06 26.5 0.0 0.15 11.8 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_17 PF13207.1 KLO08319.1 - 8.3e-06 26.6 0.0 0.15 12.8 0.0 3.8 2 0 0 2 2 2 2 AAA domain AAA_14 PF13173.1 KLO08319.1 - 3.6e-05 23.6 0.2 0.12 12.2 0.0 4.0 3 1 0 3 3 2 1 AAA domain DUF2075 PF09848.4 KLO08319.1 - 8.1e-05 21.7 0.0 0.08 11.9 0.0 2.8 3 0 0 3 3 3 1 Uncharacterized conserved protein (DUF2075) APS_kinase PF01583.15 KLO08319.1 - 0.00012 21.7 0.1 0.24 11.0 0.0 2.9 3 0 0 3 3 2 1 Adenylylsulphate kinase ABC_tran PF00005.22 KLO08319.1 - 0.00015 22.0 0.0 0.13 12.5 0.0 3.2 2 0 0 2 2 2 1 ABC transporter AAA_25 PF13481.1 KLO08319.1 - 0.00026 20.4 0.0 0.35 10.2 0.0 2.7 2 0 0 2 2 2 1 AAA domain MobB PF03205.9 KLO08319.1 - 0.00035 20.3 0.1 0.067 12.8 0.0 2.6 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_18 PF13238.1 KLO08319.1 - 0.00041 20.6 0.0 0.44 10.8 0.0 2.9 2 1 0 2 2 2 1 AAA domain Nucleoporin_N PF08801.6 KLO08319.1 - 0.0013 17.5 0.2 0.013 14.2 0.0 2.4 2 1 1 3 3 3 1 Nup133 N terminal like FtsK_SpoIIIE PF01580.13 KLO08319.1 - 0.0015 18.0 0.0 1.9 7.8 0.0 3.1 3 0 0 3 3 3 1 FtsK/SpoIIIE family ResIII PF04851.10 KLO08319.1 - 0.0018 18.1 0.0 0.027 14.3 0.0 2.3 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Arch_ATPase PF01637.13 KLO08319.1 - 0.0023 17.6 0.0 0.059 13.0 0.0 3.0 3 0 0 3 3 3 1 Archaeal ATPase Nbas_N PF15492.1 KLO08319.1 - 0.0026 16.8 0.7 1.5 7.8 0.0 3.3 2 1 0 3 3 3 1 Neuroblastoma-amplified sequence, N terminal AAA_11 PF13086.1 KLO08319.1 - 0.0035 16.9 0.0 0.21 11.1 0.0 2.5 2 0 0 2 2 2 1 AAA domain KAP_NTPase PF07693.9 KLO08319.1 - 0.0058 15.6 0.5 4.9 6.0 0.0 3.6 3 0 0 3 3 3 0 KAP family P-loop domain AAA_PrkA PF08298.6 KLO08319.1 - 0.0071 15.0 0.0 0.041 12.5 0.0 2.0 2 0 0 2 2 2 1 PrkA AAA domain AAA_28 PF13521.1 KLO08319.1 - 0.0093 15.9 0.0 3.6 7.5 0.0 2.8 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.12 KLO08319.1 - 0.012 14.9 0.0 2.5 7.4 0.0 2.9 3 0 0 3 3 2 0 IstB-like ATP binding protein ADK PF00406.17 KLO08319.1 - 0.014 15.2 0.3 3 7.7 0.0 2.9 3 0 0 3 3 2 0 Adenylate kinase Parvo_NS1 PF01057.12 KLO08319.1 - 0.014 14.2 0.0 1.6 7.5 0.0 2.9 3 0 0 3 3 3 0 Parvovirus non-structural protein NS1 Torsin PF06309.6 KLO08319.1 - 0.017 14.9 0.0 7.1 6.5 0.0 2.6 2 0 0 2 2 2 0 Torsin PD40 PF07676.7 KLO08319.1 - 0.021 14.4 0.9 8.4 6.1 0.0 4.2 4 0 0 4 4 3 0 WD40-like Beta Propeller Repeat DUF1513 PF07433.6 KLO08319.1 - 0.024 13.5 0.0 0.91 8.3 0.0 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF1513) Mg_chelatase PF01078.16 KLO08319.1 - 0.024 13.7 0.0 5.5 6.0 0.0 2.6 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI Viral_helicase1 PF01443.13 KLO08319.1 - 0.026 14.0 0.0 1.4 8.3 0.0 2.4 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase ArgK PF03308.11 KLO08319.1 - 0.029 13.1 0.0 4 6.1 0.0 2.3 2 0 0 2 2 2 0 ArgK protein MMR_HSR1 PF01926.18 KLO08319.1 - 0.03 14.2 0.0 11 5.9 0.0 2.8 2 0 0 2 2 2 0 50S ribosome-binding GTPase Gmad1 PF10647.4 KLO08319.1 - 0.043 13.2 0.2 0.25 10.7 0.1 2.2 2 0 0 2 2 2 0 Lipoprotein LpqB beta-propeller domain TrwB_AAD_bind PF10412.4 KLO08319.1 - 0.045 12.3 0.0 0.83 8.2 0.0 2.4 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain AAA_10 PF12846.2 KLO08319.1 - 0.046 13.1 0.2 11 5.3 0.0 3.0 2 1 1 3 3 3 0 AAA-like domain T2SE PF00437.15 KLO08319.1 - 0.046 12.6 0.0 0.18 10.6 0.0 1.8 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_29 PF13555.1 KLO08319.1 - 0.068 12.7 0.0 7.5 6.1 0.0 2.6 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_24 PF13479.1 KLO08319.1 - 0.073 12.6 0.4 9.2 5.7 0.0 2.9 3 0 0 3 3 2 0 AAA domain AAA_5 PF07728.9 KLO08319.1 - 0.075 12.7 0.0 5.3 6.7 0.0 2.8 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) RuvB_N PF05496.7 KLO08319.1 - 0.09 11.8 0.0 0.62 9.0 0.0 2.1 2 0 0 2 2 2 0 Holliday junction DNA helicase ruvB N-terminus cobW PF02492.14 KLO08319.1 - 0.1 12.0 0.1 1.3 8.4 0.0 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_30 PF13604.1 KLO08319.1 - 0.11 12.0 0.1 2.6 7.5 0.0 2.3 2 0 0 2 2 2 0 AAA domain KaiC PF06745.8 KLO08319.1 - 0.15 11.2 0.1 26 3.8 0.0 3.8 5 0 0 5 5 5 0 KaiC NTPase_1 PF03266.10 KLO08319.1 - 0.19 11.4 0.1 0.92 9.1 0.0 2.1 2 0 0 2 2 2 0 NTPase zf-C2H2 PF00096.21 KLO08320.1 - 2.9e-09 36.7 5.1 0.0046 17.2 0.4 3.6 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KLO08320.1 - 5.4e-09 35.7 6.6 0.026 14.8 0.4 3.7 3 0 0 3 3 3 3 C2H2-type zinc finger zf-H2C2_2 PF13465.1 KLO08320.1 - 4.5e-05 23.5 12.2 0.031 14.5 0.3 4.0 4 0 0 4 4 4 3 Zinc-finger double domain zf-BED PF02892.10 KLO08320.1 - 0.026 14.2 8.7 0.05 13.3 2.6 2.7 3 0 0 3 3 3 0 BED zinc finger IBR PF01485.16 KLO08320.1 - 1 9.3 4.5 2 8.3 0.3 2.3 2 0 0 2 2 2 0 IBR domain zf-H2C2_5 PF13909.1 KLO08320.1 - 1 9.7 8.8 0.28 11.5 0.3 3.4 3 0 0 3 3 3 0 C2H2-type zinc-finger domain UQ_con PF00179.21 KLO08323.1 - 1.3e-11 44.0 0.0 2.3e-11 43.2 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UQ_con PF00179.21 KLO08324.1 - 8.3e-10 38.2 0.0 1.9e-09 37.1 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme F-box PF00646.28 KLO08324.1 - 0.00073 19.1 0.0 0.0018 17.8 0.0 1.7 1 0 0 1 1 1 1 F-box domain BNR PF02012.15 KLO08325.1 - 1.4e-08 33.2 31.3 0.32 11.0 0.4 8.3 8 0 0 8 8 8 7 BNR/Asp-box repeat UQ_con PF00179.21 KLO08326.1 - 6.4e-08 32.1 0.0 1e-07 31.4 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme F-box PF00646.28 KLO08326.1 - 0.00076 19.0 0.0 0.0019 17.7 0.0 1.7 1 0 0 1 1 1 1 F-box domain RloB PF13707.1 KLO08326.1 - 0.14 11.7 0.0 0.34 10.5 0.0 1.6 2 0 0 2 2 2 0 RloB-like protein zf-C3H1 PF10650.4 KLO08327.1 - 2.1e-05 23.8 0.9 3.1e-05 23.3 0.6 1.3 1 0 0 1 1 1 1 Putative zinc-finger domain LysR_substrate PF03466.15 KLO08328.1 - 0.088 11.8 0.0 0.16 11.0 0.0 1.3 1 0 0 1 1 1 0 LysR substrate binding domain HLH PF00010.21 KLO08329.1 - 1.7e-07 30.8 0.0 3e-07 30.0 0.0 1.4 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Polysacc_deac_1 PF01522.16 KLO08331.1 - 1.5e-31 108.5 0.0 2.8e-31 107.7 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide deacetylase Glyco_hydro_57 PF03065.10 KLO08331.1 - 0.0017 17.3 0.0 0.0024 16.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 57 HTH_23 PF13384.1 KLO08331.1 - 0.076 12.6 0.1 0.2 11.3 0.0 1.7 2 0 0 2 2 2 0 Homeodomain-like domain DUF2360 PF10152.4 KLO08332.1 - 0.14 12.4 0.3 0.15 12.3 0.2 1.1 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein (DUF2360) FAP PF07174.6 KLO08332.1 - 2.4 7.3 12.0 3 7.0 8.3 1.1 1 0 0 1 1 1 0 Fibronectin-attachment protein (FAP) Collagen PF01391.13 KLO08333.1 - 1.2e-07 31.1 17.7 1.7e-07 30.6 12.3 1.3 1 0 0 1 1 1 1 Collagen triple helix repeat (20 copies) Period_C PF12114.3 KLO08333.1 - 1.7 8.1 11.7 2 7.9 8.1 1.1 1 0 0 1 1 1 0 Period protein 2/3C-terminal region DEC-1_N PF04625.8 KLO08333.1 - 3.2 6.3 10.1 4.5 5.8 7.0 1.2 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region Peptidase_M13_N PF05649.8 KLO08342.1 - 0.05 12.6 0.0 0.073 12.0 0.0 1.2 1 0 0 1 1 1 0 Peptidase family M13 F-box-like PF12937.2 KLO08347.1 - 7e-07 28.8 0.9 3.2e-06 26.7 0.5 2.3 2 1 0 2 2 2 1 F-box-like F-box-like PF12937.2 KLO08348.1 - 1e-07 31.5 0.1 3.9e-07 29.6 0.0 2.1 1 0 0 1 1 1 1 F-box-like F-box-like PF12937.2 KLO08349.1 - 2.6e-09 36.6 0.1 6.4e-09 35.4 0.1 1.7 1 0 0 1 1 1 1 F-box-like F-box-like PF12937.2 KLO08351.1 - 4.8e-07 29.3 0.3 4.8e-07 29.3 0.2 2.4 2 1 0 2 2 2 1 F-box-like F-box PF00646.28 KLO08351.1 - 0.19 11.4 2.8 15 5.3 0.1 3.3 3 0 0 3 3 3 0 F-box domain FtsJ PF01728.14 KLO08352.1 - 2.3e-45 154.7 0.0 2.7e-45 154.5 0.0 1.1 1 0 0 1 1 1 1 FtsJ-like methyltransferase F-box-like PF12937.2 KLO08353.1 - 3.9e-08 32.8 0.1 3.9e-08 32.8 0.0 2.2 2 2 1 3 3 3 1 F-box-like F-box PF00646.28 KLO08353.1 - 0.36 10.5 3.4 15 5.3 0.0 3.2 3 0 0 3 3 3 0 F-box domain CVNH PF08881.5 KLO08355.1 - 2.2e-22 79.2 0.9 3e-22 78.8 0.6 1.2 1 0 0 1 1 1 1 CVNH domain DUF916 PF06030.7 KLO08355.1 - 0.019 14.7 1.4 0.039 13.7 0.4 1.8 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF916) Neurokinin_B PF03823.9 KLO08355.1 - 0.11 12.2 1.0 0.18 11.6 0.2 1.7 2 0 0 2 2 2 0 Neurokinin B RVT_3 PF13456.1 KLO08356.1 - 0.054 13.2 0.0 0.077 12.7 0.0 1.2 1 0 0 1 1 1 0 Reverse transcriptase-like RNase_H PF00075.19 KLO08356.1 - 0.13 12.6 0.0 0.13 12.5 0.0 1.1 1 0 0 1 1 1 0 RNase H IucA_IucC PF04183.7 KLO08357.1 - 0.13 11.4 0.0 0.24 10.6 0.0 1.5 1 0 0 1 1 1 0 IucA / IucC family CVNH PF08881.5 KLO08358.1 - 2e-19 69.7 0.6 7.7e-19 67.8 0.4 1.8 1 1 0 1 1 1 1 CVNH domain DUF916 PF06030.7 KLO08358.1 - 0.023 14.4 1.7 2.6 7.8 0.1 2.1 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF916) DUF1659 PF07872.6 KLO08358.1 - 0.075 12.6 0.0 0.17 11.5 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1659) CVNH PF08881.5 KLO08359.1 - 8.3e-18 64.5 0.9 1.3e-17 63.9 0.6 1.3 1 0 0 1 1 1 1 CVNH domain Neurokinin_B PF03823.9 KLO08359.1 - 0.059 13.1 0.2 1.3 8.8 0.1 2.3 2 0 0 2 2 2 0 Neurokinin B Pkinase PF00069.20 KLO08360.1 - 5.3e-72 242.0 0.0 1.5e-71 240.5 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KLO08360.1 - 1.1e-35 123.0 0.0 4.6e-35 120.9 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase KA1 PF02149.14 KLO08360.1 - 2.4e-15 55.6 0.1 4e-15 54.9 0.0 1.3 1 0 0 1 1 1 1 Kinase associated domain 1 Kdo PF06293.9 KLO08360.1 - 1.6e-06 27.3 0.0 2.7e-06 26.5 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 KLO08360.1 - 2.2e-05 23.5 0.0 5.7e-05 22.2 0.0 1.7 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 KLO08360.1 - 0.00012 21.9 0.0 0.014 15.1 0.0 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family WaaY PF06176.6 KLO08360.1 - 0.0099 15.1 0.3 0.017 14.3 0.2 1.2 1 0 0 1 1 1 1 Lipopolysaccharide core biosynthesis protein (WaaY) YrbL-PhoP_reg PF10707.4 KLO08360.1 - 0.047 13.0 0.1 0.13 11.5 0.1 1.7 1 1 0 1 1 1 0 PhoP regulatory network protein YrbL RIO1 PF01163.17 KLO08360.1 - 0.11 11.8 0.1 0.56 9.5 0.0 2.0 2 0 0 2 2 2 0 RIO1 family PLAC8 PF04749.12 KLO08361.1 - 5.3e-23 81.6 8.5 6.9e-23 81.2 5.9 1.1 1 0 0 1 1 1 1 PLAC8 family RimK PF08443.6 KLO08361.1 - 0.16 11.4 0.0 0.21 11.0 0.0 1.1 1 0 0 1 1 1 0 RimK-like ATP-grasp domain Methyltransf_23 PF13489.1 KLO08362.1 - 6.8e-16 58.3 0.0 1e-15 57.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KLO08362.1 - 1e-15 57.6 0.0 3.8e-15 55.8 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KLO08362.1 - 2.7e-11 43.7 0.0 5.6e-11 42.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KLO08362.1 - 2.2e-10 41.0 0.0 1.8e-09 38.1 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KLO08362.1 - 3.8e-09 36.8 0.0 9.7e-09 35.6 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KLO08362.1 - 1.3e-06 28.7 0.0 3e-06 27.5 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 KLO08362.1 - 7.7e-05 21.8 0.0 0.00021 20.3 0.0 1.7 2 1 0 2 2 2 1 Putative methyltransferase Methyltransf_26 PF13659.1 KLO08362.1 - 0.0011 19.0 0.0 0.0018 18.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KLO08362.1 - 0.011 15.1 0.0 0.019 14.3 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain PCMT PF01135.14 KLO08362.1 - 0.033 13.7 0.0 0.07 12.6 0.0 1.5 1 1 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) FtsJ PF01728.14 KLO08362.1 - 0.048 13.6 0.0 0.072 13.0 0.0 1.3 1 0 0 1 1 1 0 FtsJ-like methyltransferase PrmA PF06325.8 KLO08362.1 - 0.074 12.1 0.0 0.11 11.5 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) GidB PF02527.10 KLO08362.1 - 0.14 11.3 0.0 0.59 9.2 0.0 1.9 1 1 0 1 1 1 0 rRNA small subunit methyltransferase G Methyltransf_2 PF00891.13 KLO08362.1 - 0.16 11.0 0.0 0.22 10.6 0.0 1.2 1 0 0 1 1 1 0 O-methyltransferase PhyH PF05721.8 KLO08364.1 - 0.086 12.8 0.0 0.18 11.7 0.0 1.6 1 0 0 1 1 1 0 Phytanoyl-CoA dioxygenase (PhyH) DUF1212 PF06738.7 KLO08366.1 - 6.3e-29 100.8 0.0 6.3e-29 100.8 0.0 3.1 3 0 0 3 3 3 1 Protein of unknown function (DUF1212) DUF3815 PF12821.2 KLO08366.1 - 1.2e-06 28.4 23.8 1.8e-06 27.9 4.6 2.7 2 0 0 2 2 2 2 Protein of unknown function (DUF3815) Ribosomal_L7Ae PF01248.21 KLO08367.1 - 1.9e-25 88.1 0.1 2.3e-25 87.9 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family PELOTA_1 PF15608.1 KLO08367.1 - 0.0099 15.6 0.0 0.015 15.0 0.0 1.4 1 0 0 1 1 1 1 PELOTA RNA binding domain DUF1212 PF06738.7 KLO08368.1 - 5.1e-29 101.1 0.2 5.1e-29 101.1 0.1 2.8 3 0 0 3 3 3 2 Protein of unknown function (DUF1212) DUF3815 PF12821.2 KLO08368.1 - 2.1e-09 37.3 11.7 2.1e-09 37.3 8.1 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF3815) Pkinase_Tyr PF07714.12 KLO08369.1 - 3.8e-68 229.3 0.0 1.6e-41 142.1 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.20 KLO08369.1 - 5.5e-66 222.3 0.0 1.8e-40 138.7 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Kinase-like PF14531.1 KLO08369.1 - 3.3e-07 29.5 0.0 0.0015 17.5 0.0 2.5 2 1 0 2 2 2 2 Kinase-like Kdo PF06293.9 KLO08369.1 - 4.4e-06 25.8 0.0 0.027 13.5 0.0 2.7 2 0 0 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KLO08369.1 - 2.8e-05 23.9 0.3 0.088 12.5 0.0 2.5 2 0 0 2 2 2 2 Phosphotransferase enzyme family RIO1 PF01163.17 KLO08369.1 - 3.4e-05 23.2 0.1 0.035 13.4 0.0 2.3 2 0 0 2 2 2 2 RIO1 family Seadorna_VP7 PF07387.6 KLO08369.1 - 0.00054 18.8 0.0 0.48 9.2 0.0 2.2 2 0 0 2 2 2 2 Seadornavirus VP7 YrbL-PhoP_reg PF10707.4 KLO08369.1 - 0.027 13.8 0.0 3.9 6.7 0.0 2.4 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL MFS_1 PF07690.11 KLO08370.1 - 3.1e-34 118.2 25.5 3.1e-34 118.2 17.7 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 KLO08370.1 - 6.9e-06 24.5 3.8 1.5e-05 23.3 2.6 1.5 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.11 KLO08371.1 - 8.8e-26 90.4 14.8 8.8e-26 90.4 10.3 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily SPC12 PF06645.8 KLO08371.1 - 1.6 8.6 5.4 0.41 10.4 0.2 2.9 2 1 1 3 3 3 0 Microsomal signal peptidase 12 kDa subunit (SPC12) DUF4118 PF13493.1 KLO08371.1 - 7.4 6.8 18.8 0.11 12.7 1.3 3.6 3 1 0 3 3 3 0 Domain of unknown function (DUF4118) Ecm33 PF12454.3 KLO08372.1 - 0.32 10.9 3.0 0.85 9.5 2.1 1.6 1 0 0 1 1 1 0 GPI-anchored cell wall organization protein Fungal_trans PF04082.13 KLO08374.1 - 3.8e-12 45.6 0.1 8.3e-12 44.5 0.1 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain HALZ PF02183.13 KLO08374.1 - 0.0026 17.4 0.5 0.015 15.0 0.1 2.2 1 1 1 2 2 2 2 Homeobox associated leucine zipper Zn_clus PF00172.13 KLO08374.1 - 0.0089 15.9 3.7 0.022 14.6 2.6 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Mito_fiss_reg PF05308.6 KLO08374.1 - 0.018 14.4 1.5 0.035 13.4 1.1 1.4 1 0 0 1 1 1 0 Mitochondrial fission regulator TBPIP PF07106.8 KLO08374.1 - 0.12 11.8 0.1 0.22 11.0 0.1 1.3 1 0 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) BatA PF07584.6 KLO08375.1 - 0.016 15.3 0.0 0.031 14.4 0.0 1.4 1 0 0 1 1 1 0 Aerotolerance regulator N-terminal NmrA PF05368.8 KLO08377.1 - 1.6e-31 109.3 0.0 3.8e-31 108.1 0.0 1.5 2 0 0 2 2 2 1 NmrA-like family NAD_binding_10 PF13460.1 KLO08377.1 - 3.8e-06 27.0 0.0 5.6e-06 26.4 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding MFS_1 PF07690.11 KLO08380.1 - 2e-20 72.8 54.7 2.4e-18 65.9 29.8 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.2 KLO08380.1 - 0.0003 20.5 0.2 0.0014 18.4 0.2 2.1 1 0 0 1 1 1 1 MFS_1 like family SurE PF01975.12 KLO08382.1 - 2.4e-36 124.9 1.2 3.5e-36 124.3 0.9 1.3 1 0 0 1 1 1 1 Survival protein SurE DUF4243 PF14027.1 KLO08383.1 - 1e-76 258.5 0.0 1.3e-76 258.2 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4243) BTB PF00651.26 KLO08384.1 - 0.00017 21.5 0.2 0.00033 20.5 0.1 1.6 1 1 0 1 1 1 1 BTB/POZ domain BTB PF00651.26 KLO08385.1 - 1.3e-05 25.1 0.1 4e-05 23.5 0.0 1.9 1 1 0 1 1 1 1 BTB/POZ domain BTB PF00651.26 KLO08386.1 - 2.9e-05 24.0 0.0 6.3e-05 22.9 0.0 1.6 1 1 0 1 1 1 1 BTB/POZ domain BTB PF00651.26 KLO08387.1 - 6.7e-06 26.0 0.1 2e-05 24.5 0.0 1.8 1 1 0 1 1 1 1 BTB/POZ domain BTB PF00651.26 KLO08388.1 - 9.8e-06 25.5 0.2 3.8e-05 23.6 0.0 2.0 2 1 0 2 2 2 1 BTB/POZ domain BTB PF00651.26 KLO08389.1 - 4.4e-05 23.4 0.0 0.00032 20.6 0.0 2.2 1 1 0 1 1 1 1 BTB/POZ domain DUF3716 PF12511.3 KLO08389.1 - 0.85 9.2 3.8 1.6 8.4 2.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3716) BTB PF00651.26 KLO08390.1 - 2.1e-05 24.4 0.1 0.00017 21.5 0.0 2.5 3 1 0 3 3 3 1 BTB/POZ domain BTB PF00651.26 KLO08391.1 - 1.6e-06 28.0 0.1 4.7e-06 26.5 0.0 1.8 2 1 0 2 2 2 1 BTB/POZ domain BTB PF00651.26 KLO08392.1 - 4.8e-07 29.7 0.1 1.1e-06 28.5 0.0 1.6 2 0 0 2 2 2 1 BTB/POZ domain BTB PF00651.26 KLO08393.1 - 7.6e-06 25.8 0.0 1.7e-05 24.7 0.0 1.6 1 0 0 1 1 1 1 BTB/POZ domain BTB PF00651.26 KLO08394.1 - 1.3e-05 25.1 0.0 0.0012 18.8 0.0 2.4 2 0 0 2 2 2 2 BTB/POZ domain CDC45 PF02724.9 KLO08394.1 - 0.099 10.6 0.6 0.13 10.3 0.4 1.1 1 0 0 1 1 1 0 CDC45-like protein CENP-X PF09415.5 KLO08396.1 - 0.15 11.9 0.2 0.44 10.4 0.0 1.7 2 0 0 2 2 2 0 CENP-S associating Centromere protein X Glyco_hydro_2 PF00703.16 KLO08399.1 - 6.1 7.3 8.4 4.3 7.8 0.0 3.4 3 0 0 3 3 3 0 Glycosyl hydrolases family 2 BTB PF00651.26 KLO08400.1 - 2.5e-06 27.4 0.1 5.9e-06 26.2 0.1 1.6 1 1 0 1 1 1 1 BTB/POZ domain BTB PF00651.26 KLO08401.1 - 5.5e-07 29.5 0.9 1.8e-06 27.9 0.3 2.2 2 1 0 2 2 2 1 BTB/POZ domain BTB PF00651.26 KLO08402.1 - 1.6e-06 28.0 1.1 1.3e-05 25.1 0.5 2.5 2 1 0 2 2 2 1 BTB/POZ domain BTB PF00651.26 KLO08403.1 - 1.2e-06 28.4 0.1 3.8e-06 26.8 0.0 1.9 2 1 0 2 2 2 1 BTB/POZ domain BTB PF00651.26 KLO08404.1 - 1.1e-06 28.5 0.1 4e-06 26.7 0.0 1.9 1 1 0 1 1 1 1 BTB/POZ domain Met_synt_B12 PF02965.12 KLO08404.1 - 0.017 14.3 0.0 0.019 14.1 0.0 1.3 1 1 0 1 1 1 0 Vitamin B12 dependent methionine synthase, activation domain GSH_synth_ATP PF03917.12 KLO08404.1 - 0.14 10.6 0.0 0.19 10.2 0.0 1.1 1 0 0 1 1 1 0 Eukaryotic glutathione synthase, ATP binding domain BTB PF00651.26 KLO08405.1 - 1.3e-06 28.3 0.1 6.5e-06 26.0 0.1 2.1 1 1 0 1 1 1 1 BTB/POZ domain OS-D PF03392.8 KLO08405.1 - 0.047 13.6 3.7 0.56 10.2 0.0 2.6 1 1 1 2 2 2 0 Insect pheromone-binding family, A10/OS-D BTB PF00651.26 KLO08406.1 - 1.2e-05 25.2 0.1 3.2e-05 23.8 0.0 1.8 1 1 0 1 1 1 1 BTB/POZ domain BTB PF00651.26 KLO08407.1 - 1.3e-05 25.0 0.5 0.00017 21.5 0.3 2.4 1 1 0 1 1 1 1 BTB/POZ domain BTB PF00651.26 KLO08408.1 - 4.3e-06 26.6 0.4 0.00022 21.1 0.1 2.9 2 1 0 2 2 2 1 BTB/POZ domain BTB PF00651.26 KLO08409.1 - 7.5e-05 22.6 1.0 0.00033 20.6 0.0 2.3 2 1 0 2 2 2 1 BTB/POZ domain BTB PF00651.26 KLO08410.1 - 1.4e-06 28.2 0.1 4e-06 26.7 0.0 1.7 1 1 0 1 1 1 1 BTB/POZ domain Prok-RING_1 PF14446.1 KLO08410.1 - 0.45 10.2 0.1 0.45 10.2 0.0 2.2 3 0 0 3 3 3 0 Prokaryotic RING finger family 1 BTB PF00651.26 KLO08411.1 - 6.9e-07 29.2 1.0 2.4e-06 27.4 0.2 2.2 2 1 0 2 2 2 1 BTB/POZ domain Ric8 PF10165.4 KLO08412.1 - 3.1e-75 253.7 0.2 3.4e-74 250.2 0.1 2.2 1 1 0 1 1 1 1 Guanine nucleotide exchange factor synembryn UvrD_C_2 PF13538.1 KLO08413.1 - 0.0044 17.1 0.0 0.0092 16.0 0.0 1.5 2 0 0 2 2 2 1 UvrD-like helicase C-terminal domain Herpes_gE PF02480.11 KLO08416.1 - 0.019 13.2 0.0 0.025 12.8 0.0 1.2 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E p450 PF00067.17 KLO08417.1 - 1.5e-200 666.5 0.0 5.3e-66 223.0 0.0 3.0 3 0 0 3 3 3 3 Cytochrome P450 ACP_syn_III PF08545.5 KLO08417.1 - 0.017 14.7 0.3 16 5.2 0.0 3.4 3 0 0 3 3 3 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III SUKH_6 PF14568.1 KLO08417.1 - 0.031 14.7 0.1 1.7 9.1 0.0 2.7 2 0 0 2 2 2 0 SMI1-KNR4 cell-wall Tape_meas_lam_C PF09718.5 KLO08417.1 - 0.083 12.8 0.1 15 5.5 0.0 3.3 3 0 0 3 3 3 0 Lambda phage tail tape-measure protein (Tape_meas_lam_C) PixA PF12306.3 KLO08417.1 - 0.085 12.7 0.1 11 5.8 0.0 3.0 3 0 0 3 3 3 0 Inclusion body protein p450 PF00067.17 KLO08418.1 - 2.2e-62 211.1 0.0 3.7e-62 210.3 0.0 1.3 1 0 0 1 1 1 1 Cytochrome P450 Toxin_55 PF15606.1 KLO08418.1 - 0.11 12.5 0.0 0.2 11.6 0.0 1.4 1 0 0 1 1 1 0 Putative toxin 55 RTA1 PF04479.8 KLO08421.1 - 1.6e-39 135.7 0.7 2.5e-39 135.1 0.5 1.3 1 0 0 1 1 1 1 RTA1 like protein ETRAMP PF09716.5 KLO08421.1 - 0.12 12.3 0.8 7.9 6.5 0.0 2.7 2 0 0 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) HMG_box PF00505.14 KLO08422.1 - 4.4e-15 55.7 0.2 5.7e-15 55.3 0.1 1.2 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 KLO08422.1 - 4.8e-06 26.8 0.1 8.4e-06 26.0 0.1 1.4 1 0 0 1 1 1 1 HMG-box domain TerB PF05099.8 KLO08423.1 - 0.12 12.1 0.0 0.22 11.2 0.0 1.4 1 0 0 1 1 1 0 Tellurite resistance protein TerB HMG_box PF00505.14 KLO08427.1 - 2.4e-11 43.7 4.8 1e-07 32.0 2.0 2.2 2 0 0 2 2 2 2 HMG (high mobility group) box HMG_box_2 PF09011.5 KLO08427.1 - 1.7e-07 31.5 5.5 3.4e-06 27.3 2.1 2.2 2 0 0 2 2 2 2 HMG-box domain Toxin_41 PF15521.1 KLO08427.1 - 0.12 11.5 0.3 0.16 11.1 0.2 1.1 1 0 0 1 1 1 0 Putative toxin 41 Methyltransf_23 PF13489.1 KLO08430.1 - 7.7e-08 32.2 0.0 1.1e-07 31.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KLO08430.1 - 9.1e-06 24.9 0.0 4.4e-05 22.7 0.0 1.9 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_11 PF08241.7 KLO08430.1 - 7.2e-05 23.1 0.0 0.00013 22.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KLO08430.1 - 0.0011 18.6 0.0 0.0027 17.3 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KLO08430.1 - 0.024 15.0 0.0 0.059 13.7 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_18 PF12847.2 KLO08430.1 - 0.11 13.0 0.0 0.33 11.5 0.0 1.8 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.7 KLO08431.1 - 3.2e-10 40.3 0.0 6e-10 39.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KLO08431.1 - 3.1e-09 36.6 0.0 2e-08 33.9 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KLO08431.1 - 1.5e-07 31.2 0.0 2e-07 30.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KLO08431.1 - 2.2e-07 30.2 0.0 9.4e-07 28.1 0.0 1.9 2 1 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.1 KLO08431.1 - 2.4e-05 24.6 0.0 6.8e-05 23.1 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KLO08431.1 - 0.0014 19.0 0.0 0.0047 17.3 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KLO08431.1 - 0.0079 16.7 0.1 0.11 13.0 0.1 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.10 KLO08431.1 - 0.0094 15.5 0.0 0.013 15.1 0.0 1.3 1 0 0 1 1 1 1 Hypothetical methyltransferase PrmA PF06325.8 KLO08431.1 - 0.023 13.8 0.0 0.036 13.1 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_16 PF10294.4 KLO08431.1 - 0.046 13.1 0.0 0.073 12.5 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase Methyltransf_23 PF13489.1 KLO08432.1 - 5.9e-13 48.8 0.0 8.7e-13 48.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KLO08432.1 - 4.5e-11 42.5 0.0 7.8e-10 38.5 0.0 2.3 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 KLO08432.1 - 7.4e-11 42.4 0.0 1.4e-10 41.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KLO08432.1 - 2.1e-08 33.5 0.0 8.2e-08 31.6 0.0 1.8 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.7 KLO08432.1 - 3.3e-05 24.2 0.0 0.00011 22.5 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KLO08432.1 - 0.00015 22.0 0.0 0.00034 20.9 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.10 KLO08432.1 - 0.00094 18.8 0.0 0.0051 16.4 0.0 1.9 2 0 0 2 2 2 1 Hypothetical methyltransferase Methyltransf_18 PF12847.2 KLO08432.1 - 0.0036 17.8 0.0 0.11 13.1 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KLO08432.1 - 0.035 14.1 0.0 0.15 12.1 0.0 1.9 1 1 0 1 1 1 0 Methyltransferase domain FtsJ PF01728.14 KLO08432.1 - 0.064 13.2 0.0 0.13 12.2 0.0 1.5 1 0 0 1 1 1 0 FtsJ-like methyltransferase LSM PF01423.17 KLO08433.1 - 1.6e-18 65.9 0.2 2.2e-18 65.5 0.2 1.2 1 0 0 1 1 1 1 LSM domain DUF4050 PF13259.1 KLO08435.1 - 0.00014 21.7 0.0 0.00031 20.6 0.0 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF4050) Methyltransf_11 PF08241.7 KLO08436.1 - 3.1e-10 40.3 0.0 5e-10 39.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KLO08436.1 - 2.3e-09 37.0 0.0 3.9e-09 36.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KLO08436.1 - 2.6e-09 37.0 0.0 3.7e-09 36.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KLO08436.1 - 1.1e-06 27.9 0.0 1.8e-06 27.2 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.1 KLO08436.1 - 4.7e-06 26.8 0.0 8.3e-06 26.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KLO08436.1 - 6.9e-05 23.2 0.0 0.00011 22.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KLO08436.1 - 0.00081 19.9 0.0 0.0015 19.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.14 KLO08436.1 - 0.0089 16.0 0.0 0.016 15.1 0.0 1.5 1 1 0 1 1 1 1 FtsJ-like methyltransferase TPMT PF05724.6 KLO08436.1 - 0.016 14.6 0.0 0.025 13.9 0.0 1.3 1 0 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) Methyltransf_26 PF13659.1 KLO08436.1 - 0.12 12.3 0.0 0.55 10.2 0.0 1.9 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.7 KLO08437.1 - 6.9e-10 39.2 0.0 1.5e-09 38.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KLO08437.1 - 2e-09 37.2 0.0 7.5e-09 35.3 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KLO08437.1 - 9.1e-09 34.7 0.0 4.9e-08 32.3 0.0 2.1 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.1 KLO08437.1 - 1.7e-08 34.3 0.0 2.7e-08 33.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KLO08437.1 - 0.00032 21.0 0.0 0.00071 19.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KLO08437.1 - 0.00071 20.0 0.0 0.0022 18.4 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KLO08437.1 - 0.0048 17.4 0.1 0.087 13.4 0.0 2.5 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_8 PF05148.10 KLO08437.1 - 0.0071 16.0 0.0 0.02 14.5 0.0 1.8 1 1 0 1 1 1 1 Hypothetical methyltransferase Methyltransf_16 PF10294.4 KLO08437.1 - 0.025 14.0 0.0 0.039 13.3 0.0 1.2 1 0 0 1 1 1 0 Putative methyltransferase PrmA PF06325.8 KLO08437.1 - 0.15 11.1 0.1 0.31 10.1 0.0 1.4 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) adh_short PF00106.20 KLO08438.1 - 1.2e-14 54.5 0.0 2.1e-14 53.8 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KLO08438.1 - 5.6e-06 26.1 0.1 1e-05 25.3 0.1 1.5 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 KLO08438.1 - 0.0011 18.7 0.0 0.0019 18.0 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 KLO08438.1 - 0.0012 18.8 0.9 0.011 15.8 0.5 2.5 2 1 1 3 3 3 1 NADH(P)-binding 3HCDH_N PF02737.13 KLO08438.1 - 0.026 14.1 0.1 0.042 13.4 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Shikimate_DH PF01488.15 KLO08438.1 - 0.034 14.2 0.0 0.099 12.7 0.0 1.8 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase ADH_zinc_N PF00107.21 KLO08438.1 - 0.06 12.9 0.2 0.13 11.7 0.1 1.6 1 0 0 1 1 1 0 Zinc-binding dehydrogenase Eno-Rase_NADH_b PF12242.3 KLO08438.1 - 0.072 12.8 0.1 0.28 10.9 0.0 1.9 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Herpes_UL43 PF05072.8 KLO08439.1 - 0.42 9.3 7.3 1.2 7.7 0.1 3.2 2 1 1 3 3 3 0 Herpesvirus UL43 protein Pox_A14 PF05767.7 KLO08440.1 - 0.24 11.3 5.7 4.8 7.2 0.0 3.3 2 1 1 3 3 3 0 Poxvirus virion envelope protein A14 Methyltransf_23 PF13489.1 KLO08441.1 - 3.8e-09 36.4 0.0 5.7e-09 35.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KLO08441.1 - 2.3e-07 31.2 0.0 5.7e-07 29.9 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.13 KLO08441.1 - 9.9e-06 24.8 0.0 0.00012 21.2 0.0 2.5 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.1 KLO08441.1 - 0.00028 20.5 0.0 0.0012 18.5 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KLO08442.1 - 2.5e-13 50.0 0.0 3.4e-13 49.6 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KLO08442.1 - 4e-10 40.0 0.0 2.2e-09 37.6 0.0 2.1 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 KLO08442.1 - 7.2e-09 35.4 0.0 2.7e-08 33.5 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KLO08442.1 - 9.9e-09 34.6 0.0 2.1e-08 33.5 0.0 1.5 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.1 KLO08442.1 - 3.4e-08 33.7 0.0 7.1e-08 32.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.14 KLO08442.1 - 7.9e-06 25.9 0.0 0.00023 21.2 0.0 2.1 1 1 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_12 PF08242.7 KLO08442.1 - 3e-05 24.4 0.0 0.0001 22.6 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KLO08442.1 - 0.00024 21.1 0.0 0.0019 18.2 0.0 2.3 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 KLO08442.1 - 0.0045 17.5 0.0 0.023 15.2 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain TPMT PF05724.6 KLO08442.1 - 0.005 16.2 0.0 0.008 15.6 0.0 1.5 1 1 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) Methyltransf_8 PF05148.10 KLO08442.1 - 0.089 12.4 0.0 0.14 11.7 0.0 1.4 1 0 0 1 1 1 0 Hypothetical methyltransferase Methyltransf_23 PF13489.1 KLO08443.1 - 2.7e-13 49.9 0.0 4e-13 49.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KLO08443.1 - 4.7e-13 49.4 0.0 8.3e-13 48.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KLO08443.1 - 5.9e-13 48.6 0.0 8.2e-13 48.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KLO08443.1 - 5.7e-10 38.7 0.0 2.6e-09 36.5 0.0 1.9 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.7 KLO08443.1 - 1.3e-08 35.1 0.0 2.2e-08 34.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KLO08443.1 - 3e-07 30.7 0.0 4.9e-07 30.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KLO08443.1 - 1.2e-06 29.0 0.0 2.6e-06 27.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain TPMT PF05724.6 KLO08443.1 - 0.0063 15.9 0.0 0.011 15.2 0.0 1.5 1 0 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) Methyltransf_26 PF13659.1 KLO08443.1 - 0.01 15.8 0.0 0.041 13.9 0.0 2.0 2 1 0 2 2 2 1 Methyltransferase domain CMAS PF02353.15 KLO08443.1 - 0.014 14.4 0.0 0.021 13.8 0.0 1.1 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltransf_4 PF02390.12 KLO08443.1 - 0.022 13.8 0.0 0.4 9.6 0.0 2.6 3 0 0 3 3 3 0 Putative methyltransferase Methyltransf_8 PF05148.10 KLO08443.1 - 0.061 12.9 0.0 0.11 12.1 0.0 1.3 1 0 0 1 1 1 0 Hypothetical methyltransferase Peptidase_S28 PF05577.7 KLO08444.1 - 1.2e-54 185.5 5.6 7.7e-54 182.9 3.9 1.8 1 1 0 1 1 1 1 Serine carboxypeptidase S28 Peptidase_S9 PF00326.16 KLO08444.1 - 0.00042 19.6 0.0 0.00087 18.5 0.0 1.5 1 0 0 1 1 1 1 Prolyl oligopeptidase family EVE PF01878.13 KLO08445.1 - 7.5e-48 162.1 0.2 9.8e-48 161.8 0.1 1.1 1 0 0 1 1 1 1 EVE domain RRM_1 PF00076.17 KLO08447.1 - 1.2e-32 111.3 0.0 3.5e-16 58.5 0.0 4.6 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KLO08447.1 - 1.5e-19 69.7 0.0 5.3e-11 42.3 0.0 3.8 3 1 0 3 3 3 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KLO08447.1 - 3.2e-14 52.5 0.0 1.3e-09 37.7 0.0 3.4 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 KLO08447.1 - 1e-05 25.2 0.0 3.4e-05 23.6 0.0 1.9 2 0 0 2 2 2 1 RNA binding motif Nup35_RRM_2 PF14605.1 KLO08447.1 - 0.00066 19.3 0.0 0.0018 17.9 0.0 1.8 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif DUF2271 PF10029.4 KLO08447.1 - 0.11 11.9 0.0 1.3 8.5 0.1 2.4 2 0 0 2 2 2 0 Predicted periplasmic protein (DUF2271) Limkain-b1 PF11608.3 KLO08447.1 - 0.13 11.9 0.0 0.69 9.7 0.0 2.0 2 0 0 2 2 2 0 Limkain b1 Band_7 PF01145.20 KLO08448.1 - 3.2e-25 89.0 3.6 4.8e-25 88.5 2.5 1.2 1 0 0 1 1 1 1 SPFH domain / Band 7 family Serglycin PF04360.7 KLO08448.1 - 0.024 14.3 0.5 0.042 13.5 0.3 1.4 1 0 0 1 1 1 0 Serglycin DUF3246 PF11596.3 KLO08448.1 - 4.4 6.5 6.5 8.1 5.6 4.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3246) zf-C3HC4_3 PF13920.1 KLO08450.1 - 1.7e-06 27.5 12.8 2.7e-06 26.9 8.8 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KLO08450.1 - 1.3e-05 24.9 15.3 2e-05 24.3 10.6 1.3 1 0 0 1 1 1 1 Ring finger domain IncA PF04156.9 KLO08450.1 - 0.0001 21.9 6.1 0.0001 21.9 4.3 2.1 2 0 0 2 2 2 1 IncA protein zf-RING_5 PF14634.1 KLO08450.1 - 0.00016 21.3 15.0 0.00025 20.6 10.4 1.3 1 0 0 1 1 1 1 zinc-RING finger domain DUF904 PF06005.7 KLO08450.1 - 0.0003 20.9 7.9 0.049 13.9 0.0 2.9 3 0 0 3 3 2 2 Protein of unknown function (DUF904) DivIC PF04977.10 KLO08450.1 - 0.0018 17.6 5.5 0.25 10.8 0.1 2.5 2 0 0 2 2 2 2 Septum formation initiator Reo_sigmaC PF04582.7 KLO08450.1 - 0.0021 17.3 0.4 0.003 16.8 0.3 1.2 1 0 0 1 1 1 1 Reovirus sigma C capsid protein DUF4407 PF14362.1 KLO08450.1 - 0.0023 16.9 3.6 0.0053 15.7 2.5 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4407) zf-C3HC4 PF00097.20 KLO08450.1 - 0.0025 17.4 17.0 0.0042 16.7 11.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KLO08450.1 - 0.0032 17.4 16.0 0.0051 16.8 11.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) DUF1192 PF06698.6 KLO08450.1 - 0.0037 17.0 1.7 0.46 10.3 0.1 3.0 2 1 0 2 2 2 1 Protein of unknown function (DUF1192) TFIIA PF03153.8 KLO08450.1 - 0.0038 17.2 9.1 0.0059 16.5 6.3 1.3 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit TMF_DNA_bd PF12329.3 KLO08450.1 - 0.0056 16.4 8.0 0.69 9.7 3.2 2.8 2 0 0 2 2 2 1 TATA element modulatory factor 1 DNA binding Syntaxin_2 PF14523.1 KLO08450.1 - 0.012 15.6 2.8 0.021 14.8 1.9 1.5 1 0 0 1 1 1 0 Syntaxin-like protein CENP-Q PF13094.1 KLO08450.1 - 0.017 15.1 7.3 0.73 9.8 0.0 2.8 3 0 0 3 3 2 0 CENP-Q, a CENPA-CAD centromere complex subunit FlxA PF14282.1 KLO08450.1 - 0.028 14.3 13.0 0.082 12.8 1.7 3.0 2 1 1 3 3 2 0 FlxA-like protein Prok-RING_4 PF14447.1 KLO08450.1 - 0.028 13.9 7.1 0.055 13.0 4.9 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_4 PF14570.1 KLO08450.1 - 0.03 13.8 14.3 0.056 13.0 9.9 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING_UBOX PF13445.1 KLO08450.1 - 0.045 13.4 8.7 0.13 12.0 6.0 1.8 1 1 0 1 1 1 0 RING-type zinc-finger HALZ PF02183.13 KLO08450.1 - 0.081 12.6 4.7 0.79 9.4 0.2 2.7 2 0 0 2 2 2 0 Homeobox associated leucine zipper DUF972 PF06156.8 KLO08450.1 - 0.086 13.1 11.4 0.93 9.8 0.1 3.1 1 1 1 2 2 2 0 Protein of unknown function (DUF972) FlaC_arch PF05377.6 KLO08450.1 - 0.14 12.1 2.1 1.3 9.0 0.0 2.6 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) DivIVA PF05103.8 KLO08450.1 - 0.15 12.0 0.2 0.15 12.0 0.1 3.5 4 0 0 4 4 4 0 DivIVA protein APG6 PF04111.7 KLO08450.1 - 0.18 10.8 8.4 0.013 14.5 1.8 1.9 2 0 0 2 2 2 0 Autophagy protein Apg6 COG5 PF10392.4 KLO08450.1 - 0.22 11.4 2.6 0.53 10.2 1.8 1.6 1 1 0 1 1 1 0 Golgi transport complex subunit 5 GAS PF13851.1 KLO08450.1 - 0.28 10.3 7.1 2.4 7.3 4.9 2.2 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding Prefoldin_2 PF01920.15 KLO08450.1 - 0.5 10.1 5.8 17 5.2 2.1 2.6 2 0 0 2 2 2 0 Prefoldin subunit DUF1664 PF07889.7 KLO08450.1 - 0.52 10.1 2.4 1.5 8.6 1.5 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) zf-RING_6 PF14835.1 KLO08450.1 - 0.55 10.0 6.8 1.1 9.1 4.7 1.4 1 0 0 1 1 1 0 zf-RING of BARD1-type protein Syntaxin PF00804.20 KLO08450.1 - 1.3 9.1 9.8 14 5.9 6.5 2.5 1 1 0 1 1 1 0 Syntaxin Spectrin PF00435.16 KLO08450.1 - 1.5 9.1 5.9 14 6.0 0.2 3.6 2 1 1 3 3 2 0 Spectrin repeat bZIP_1 PF00170.16 KLO08450.1 - 1.7 8.6 11.5 1.7 8.6 0.0 3.2 3 0 0 3 3 3 0 bZIP transcription factor ADIP PF11559.3 KLO08450.1 - 1.8 8.4 13.8 0.55 10.1 5.9 2.4 2 1 0 2 2 1 0 Afadin- and alpha -actinin-Binding Jnk-SapK_ap_N PF09744.4 KLO08450.1 - 2.2 8.2 7.0 4.4 7.2 1.6 2.4 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 DUF4200 PF13863.1 KLO08450.1 - 2.6 8.0 12.0 1.4 8.8 0.1 3.2 3 0 0 3 3 2 0 Domain of unknown function (DUF4200) DUF4140 PF13600.1 KLO08450.1 - 2.8 8.4 9.2 3.8 7.9 0.3 2.8 2 1 1 3 3 2 0 N-terminal domain of unknown function (DUF4140) BRE1 PF08647.6 KLO08450.1 - 2.9 7.9 9.3 1.3 9.0 0.5 2.7 3 0 0 3 3 2 0 BRE1 E3 ubiquitin ligase ATG16 PF08614.6 KLO08450.1 - 3.3 7.4 14.1 0.23 11.2 5.3 2.1 2 1 0 2 2 2 0 Autophagy protein 16 (ATG16) Rab5-bind PF09311.6 KLO08450.1 - 3.5 7.4 15.9 0.17 11.7 3.1 3.3 2 2 0 2 2 2 0 Rabaptin-like protein Mnd1 PF03962.10 KLO08450.1 - 3.5 7.2 9.5 0.17 11.5 2.5 1.8 2 0 0 2 2 1 0 Mnd1 family RhoGEF PF00621.15 KLO08451.1 - 1.6e-33 116.0 0.0 3.6e-33 114.9 0.0 1.6 1 0 0 1 1 1 1 RhoGEF domain TPR_MLP1_2 PF07926.7 KLO08451.1 - 0.044 13.5 4.5 0.12 12.1 3.1 1.7 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein EzrA PF06160.7 KLO08451.1 - 0.056 11.6 1.7 0.093 10.8 1.2 1.3 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA DUF972 PF06156.8 KLO08451.1 - 2.1 8.7 6.6 18 5.7 1.1 2.9 1 1 1 2 2 2 0 Protein of unknown function (DUF972) IncA PF04156.9 KLO08451.1 - 6.2 6.3 5.9 17 4.9 4.1 1.7 1 0 0 1 1 1 0 IncA protein F-box-like PF12937.2 KLO08452.1 - 4.4e-08 32.7 0.5 3.5e-07 29.8 0.7 2.2 2 1 0 2 2 2 1 F-box-like zf-DHHC PF01529.15 KLO08453.1 - 6.5 6.1 5.9 10 5.4 4.1 1.3 1 0 0 1 1 1 0 DHHC palmitoyltransferase adh_short PF00106.20 KLO08455.1 - 1.1e-18 67.6 0.0 2e-18 66.8 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KLO08455.1 - 3.3e-07 30.1 0.2 7.6e-07 28.9 0.2 1.5 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 KLO08455.1 - 4.3e-07 29.6 0.0 5.6e-07 29.2 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short_C2 PF13561.1 KLO08455.1 - 3.4e-06 27.0 0.0 5.4e-06 26.3 0.0 1.4 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 KLO08455.1 - 0.0012 18.9 0.6 0.008 16.1 0.2 2.4 2 2 0 2 2 2 1 NADH(P)-binding Shikimate_DH PF01488.15 KLO08455.1 - 0.0038 17.3 0.0 0.013 15.6 0.0 1.9 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase NAD_binding_4 PF07993.7 KLO08455.1 - 0.01 14.7 0.2 0.021 13.7 0.1 1.6 1 1 0 1 1 1 0 Male sterility protein DFP PF04127.10 KLO08455.1 - 0.01 15.4 1.0 0.036 13.6 0.4 2.1 2 1 0 2 2 2 0 DNA / pantothenate metabolism flavoprotein ADH_zinc_N PF00107.21 KLO08455.1 - 0.014 14.9 0.2 0.17 11.4 0.1 2.3 2 0 0 2 2 2 0 Zinc-binding dehydrogenase 3HCDH_N PF02737.13 KLO08455.1 - 0.015 15.0 0.1 0.027 14.1 0.1 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Wax2_C PF12076.3 KLO08455.1 - 0.14 11.8 0.3 0.35 10.5 0.0 1.8 2 0 0 2 2 2 0 WAX2 C-terminal domain Myb_DNA-binding PF00249.26 KLO08456.1 - 6.4e-22 77.3 8.1 1.8e-10 40.6 0.2 4.4 4 0 0 4 4 4 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 KLO08456.1 - 1.9e-16 59.9 2.7 3.2e-10 39.9 0.1 4.2 3 2 1 4 4 4 2 Myb-like DNA-binding domain Myb_DNA-bind_4 PF13837.1 KLO08456.1 - 0.0022 18.0 4.7 0.0022 18.0 3.3 4.1 2 2 1 3 3 3 1 Myb/SANT-like DNA-binding domain Rap1_C PF11626.3 KLO08456.1 - 0.02 14.7 3.2 0.66 9.8 2.2 2.6 1 1 0 1 1 1 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain SurA_N PF09312.6 KLO08456.1 - 0.027 14.3 0.9 0.44 10.4 0.0 2.9 3 0 0 3 3 3 0 SurA N-terminal domain MADF_DNA_bdg PF10545.4 KLO08456.1 - 0.32 11.2 5.7 15 5.8 0.1 3.8 2 1 1 3 3 3 0 Alcohol dehydrogenase transcription factor Myb/SANT-like HTH_32 PF13565.1 KLO08456.1 - 1.8 9.4 4.5 4 8.3 0.5 3.4 3 1 1 4 4 4 0 Homeodomain-like domain DUF1117 PF06547.7 KLO08456.1 - 2.1 8.4 7.3 4.8 7.2 3.3 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1117) DUF1844 PF08899.6 KLO08458.1 - 0.011 15.6 0.1 0.027 14.4 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF1844) DUF498 PF04430.9 KLO08459.1 - 1.3e-26 92.3 0.0 1.8e-26 91.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF498/DUF598) FadR_C PF07840.7 KLO08462.1 - 0.028 14.0 0.1 0.075 12.6 0.0 1.6 1 0 0 1 1 1 0 FadR C-terminal domain Tet_JBP PF12851.2 KLO08463.1 - 5.7e-12 45.2 0.0 6.8e-12 45.0 0.0 1.1 1 0 0 1 1 1 1 Oxygenase domain of the 2OGFeDO superfamily F-box-like PF12937.2 KLO08466.1 - 1.4e-07 31.0 0.0 3.3e-07 29.8 0.0 1.7 1 0 0 1 1 1 1 F-box-like F-box-like PF12937.2 KLO08467.1 - 1.5e-07 31.0 0.0 3.8e-07 29.7 0.0 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KLO08467.1 - 0.05 13.2 1.4 0.82 9.4 1.0 2.6 1 1 0 1 1 1 0 F-box domain F-box-like PF12937.2 KLO08468.1 - 2e-07 30.6 0.0 3.9e-07 29.6 0.0 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KLO08468.1 - 0.0073 15.9 2.3 0.022 14.3 0.4 2.6 2 1 0 2 2 2 1 F-box domain F-box-like PF12937.2 KLO08470.1 - 2.6e-06 27.0 0.1 5.5e-06 26.0 0.0 1.6 1 0 0 1 1 1 1 F-box-like F-box-like PF12937.2 KLO08471.1 - 0.00011 21.7 0.1 0.00065 19.3 0.0 2.3 2 0 0 2 2 2 1 F-box-like F-box-like PF12937.2 KLO08472.1 - 9.6e-07 28.4 1.9 3.5e-06 26.6 0.2 2.6 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 KLO08472.1 - 0.002 17.7 0.0 0.0073 15.9 0.0 2.0 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 KLO08474.1 - 1.2e-08 34.5 1.1 2.8e-08 33.3 0.1 2.2 2 0 0 2 2 2 1 F-box-like F-box-like PF12937.2 KLO08475.1 - 0.008 15.8 0.0 0.023 14.4 0.0 1.9 1 0 0 1 1 1 1 F-box-like Phage_DsbA PF11126.3 KLO08475.1 - 0.013 15.5 0.0 0.027 14.5 0.0 1.4 1 0 0 1 1 1 0 Transcriptional regulator DsbA F-box-like PF12937.2 KLO08476.1 - 1.2e-05 24.9 1.4 4e-05 23.2 0.2 2.4 2 0 0 2 2 2 1 F-box-like F-box-like PF12937.2 KLO08477.1 - 1.7e-05 24.4 0.1 3.9e-05 23.2 0.0 1.7 1 0 0 1 1 1 1 F-box-like ArfGap PF01412.13 KLO08478.1 - 1.4e-32 111.9 0.4 1.4e-32 111.9 0.3 1.9 2 0 0 2 2 2 1 Putative GTPase activating protein for Arf eIF3_subunit PF08597.5 KLO08478.1 - 0.49 9.9 0.0 0.49 9.9 0.0 2.6 2 0 0 2 2 2 0 Translation initiation factor eIF3 subunit DRY_EERY PF09750.4 KLO08478.1 - 1 9.4 5.7 2.7 8.0 4.0 1.7 1 0 0 1 1 1 0 Alternative splicing regulator F-box-like PF12937.2 KLO08479.1 - 0.00064 19.3 2.7 0.001 18.7 0.1 2.6 2 1 1 3 3 3 1 F-box-like DUF1097 PF06496.6 KLO08480.1 - 0.085 12.6 0.1 0.085 12.6 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1097) PufQ PF05398.6 KLO08480.1 - 0.12 12.4 0.5 0.28 11.2 0.3 1.6 1 0 0 1 1 1 0 PufQ cytochrome subunit NUC173 PF08161.7 KLO08482.1 - 0.15 11.4 0.0 2.5 7.4 0.0 2.0 2 0 0 2 2 2 0 NUC173 domain Pkinase PF00069.20 KLO08483.1 - 5e-37 127.4 0.0 6.9e-37 127.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KLO08483.1 - 1.3e-34 119.4 0.0 1.7e-34 119.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KLO08483.1 - 0.00034 19.6 0.0 0.00056 18.9 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Phage_NinH PF06322.6 KLO08483.1 - 0.093 12.3 0.0 0.2 11.3 0.0 1.5 1 0 0 1 1 1 0 Phage NinH protein Pkinase PF00069.20 KLO08484.1 - 3.9e-42 144.2 0.0 5.8e-42 143.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KLO08484.1 - 9.5e-38 129.7 0.0 1.4e-37 129.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 KLO08484.1 - 0.0016 18.2 0.0 0.0067 16.1 0.0 1.8 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.1 KLO08484.1 - 0.0059 15.5 0.0 0.01 14.8 0.0 1.3 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.17 KLO08484.1 - 0.035 13.4 0.3 0.32 10.3 0.2 2.2 1 1 0 1 1 1 0 RIO1 family EcKinase PF02958.15 KLO08484.1 - 0.078 12.1 0.1 10 5.1 0.0 2.1 2 0 0 2 2 2 0 Ecdysteroid kinase Tachystatin_A PF11406.3 KLO08484.1 - 0.1 12.4 0.2 0.39 10.5 0.2 2.1 1 0 0 1 1 1 0 Antimicrobial peptide tachystatin A IMS_C PF11799.3 KLO08487.1 - 0.0072 16.2 0.3 0.017 15.0 0.2 1.6 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain Phage_GPA PF05840.8 KLO08487.1 - 0.051 12.2 0.1 0.11 11.2 0.1 1.4 1 0 0 1 1 1 0 Bacteriophage replication gene A protein (GPA) CCER1 PF15482.1 KLO08489.1 - 0.0088 15.7 3.7 0.012 15.2 2.6 1.1 1 0 0 1 1 1 1 Coiled-coil domain-containing glutamate-rich protein family 1 Uricase PF01014.13 KLO08491.1 - 0.034 14.2 0.0 9.1 6.3 0.0 2.3 1 1 1 2 2 2 0 Uricase Pkinase PF00069.20 KLO08492.1 - 4e-45 153.9 0.0 6.4e-45 153.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KLO08492.1 - 1.7e-36 125.6 0.0 2.4e-36 125.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KLO08492.1 - 6e-06 25.4 0.0 1e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 KLO08492.1 - 0.053 12.5 0.0 0.094 11.7 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.20 KLO08493.1 - 1.4e-38 132.5 0.0 2.2e-38 131.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KLO08493.1 - 1.8e-33 115.7 0.0 3.5e-31 108.2 0.0 2.1 1 1 1 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 KLO08493.1 - 0.00021 20.3 0.0 0.00034 19.6 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 KLO08493.1 - 0.046 12.7 0.0 0.24 10.4 0.0 2.1 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family zf-MYND PF01753.13 KLO08494.1 - 2.3e-09 36.9 11.4 2.3e-09 36.9 7.9 1.9 2 0 0 2 2 2 1 MYND finger DUF4396 PF14342.1 KLO08494.1 - 0.15 12.2 0.3 0.29 11.2 0.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4396) zf-MYND PF01753.13 KLO08495.1 - 9.7e-10 38.1 12.4 9.7e-10 38.1 8.6 2.3 3 0 0 3 3 3 1 MYND finger Pkinase PF00069.20 KLO08496.1 - 4.5e-46 157.1 0.0 6e-46 156.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KLO08496.1 - 1.2e-38 132.6 0.0 1.6e-38 132.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KLO08496.1 - 1.5e-06 27.4 0.0 2.3e-06 26.8 0.0 1.2 1 0 0 1 1 1 1 Kinase-like zf-MYND PF01753.13 KLO08497.1 - 4.1e-10 39.3 9.4 4.1e-10 39.3 6.5 2.2 2 0 0 2 2 2 1 MYND finger TFCD_C PF12612.3 KLO08498.1 - 0.026 13.9 0.0 0.035 13.5 0.0 1.1 1 0 0 1 1 1 0 Tubulin folding cofactor D C terminal zf-MYND PF01753.13 KLO08500.1 - 9.5e-08 31.7 14.9 9.5e-08 31.7 10.3 2.1 2 0 0 2 2 2 1 MYND finger zf-MYND PF01753.13 KLO08501.1 - 2.1e-10 40.2 11.0 2.1e-10 40.2 7.7 1.9 2 0 0 2 2 2 1 MYND finger Ecl1 PF12855.2 KLO08501.1 - 0.15 11.4 8.7 0.13 11.6 4.7 1.9 1 1 1 2 2 2 0 Life-span regulatory factor zf-Mss51 PF13824.1 KLO08501.1 - 0.35 10.7 6.8 1.1 9.1 4.7 1.9 1 0 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 zf-MYND PF01753.13 KLO08502.1 - 1.9e-09 37.2 14.8 4.8e-09 35.9 10.3 1.7 1 0 0 1 1 1 1 MYND finger Peptidase_M16_C PF05193.16 KLO08502.1 - 0.17 11.5 0.0 0.92 9.1 0.0 2.0 1 1 0 1 1 1 0 Peptidase M16 inactive domain zf-MYND PF01753.13 KLO08503.1 - 1.2e-09 37.8 16.5 3.4e-09 36.4 8.9 3.2 3 0 0 3 3 3 1 MYND finger Daxx PF03344.10 KLO08504.1 - 0.0013 17.3 22.3 0.0016 17.0 15.4 1.2 1 0 0 1 1 1 1 Daxx Family Nop14 PF04147.7 KLO08504.1 - 0.051 11.4 32.1 0.067 11.1 22.2 1.1 1 0 0 1 1 1 0 Nop14-like family Astro_capsid PF03115.9 KLO08504.1 - 0.1 10.8 12.3 0.13 10.5 8.5 1.1 1 0 0 1 1 1 0 Astrovirus capsid protein precursor Hid1 PF12722.2 KLO08504.1 - 0.14 9.8 8.8 0.16 9.6 6.1 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Ycf1 PF05758.7 KLO08504.1 - 0.52 7.9 5.2 0.59 7.7 3.6 1.0 1 0 0 1 1 1 0 Ycf1 Spore_coat_CotO PF14153.1 KLO08504.1 - 0.7 9.3 9.2 1.2 8.5 6.4 1.4 1 0 0 1 1 1 0 Spore coat protein CotO BUD22 PF09073.5 KLO08504.1 - 0.78 8.7 37.3 0.98 8.4 25.9 1.1 1 0 0 1 1 1 0 BUD22 DUF2146 PF10220.4 KLO08504.1 - 1.2 7.0 13.9 1.5 6.7 9.6 1.0 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2146) Macoilin PF09726.4 KLO08504.1 - 2.1 6.5 7.9 2.7 6.1 5.5 1.1 1 0 0 1 1 1 0 Transmembrane protein CENP-T PF15511.1 KLO08504.1 - 4.6 6.3 22.9 6.1 5.9 15.9 1.1 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T Zip PF02535.17 KLO08504.1 - 6.6 5.6 5.5 9.6 5.1 3.8 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter DUF1510 PF07423.6 KLO08504.1 - 6.9 5.9 31.8 9.6 5.4 22.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) zf-MYND PF01753.13 KLO08506.1 - 1.1e-09 37.9 11.7 2.7e-09 36.7 8.1 1.7 1 0 0 1 1 1 1 MYND finger Daxx PF03344.10 KLO08506.1 - 9 4.6 24.4 14 4.0 16.9 1.2 1 0 0 1 1 1 0 Daxx Family MoCF_biosynth PF00994.19 KLO08507.1 - 1.4e-27 95.8 0.0 1.7e-27 95.6 0.0 1.0 1 0 0 1 1 1 1 Probable molybdopterin binding domain GDPD PF03009.12 KLO08510.1 - 3.1e-32 112.0 0.0 4.6e-32 111.5 0.0 1.3 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family GDPD_2 PF13653.1 KLO08510.1 - 1.7e-05 24.8 0.2 1.7e-05 24.8 0.1 2.1 2 0 0 2 2 2 1 Glycerophosphoryl diester phosphodiesterase family Acyltransferase PF01553.16 KLO08512.1 - 7.8e-35 119.1 0.0 1.1e-34 118.6 0.0 1.2 1 0 0 1 1 1 1 Acyltransferase Nop14 PF04147.7 KLO08513.1 - 4.1e-246 818.9 19.3 4.8e-246 818.7 13.4 1.0 1 0 0 1 1 1 1 Nop14-like family Rubi_NSP_C PF12601.3 KLO08514.1 - 0.38 10.6 1.5 28 4.6 0.0 3.1 3 0 0 3 3 3 0 Rubivirus non-structural protein Pheromone PF08015.6 KLO08515.1 - 2.4 9.0 0.0 2.4 9.0 0.0 3.5 5 0 0 5 5 5 0 Fungal mating-type pheromone Peptidase_S10 PF00450.17 KLO08516.1 - 1.6e-100 337.2 0.0 1.9e-100 336.9 0.0 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase MtaB PF12176.3 KLO08516.1 - 0.031 12.7 0.1 0.043 12.2 0.1 1.1 1 0 0 1 1 1 0 Methanol-cobalamin methyltransferase B subunit Mgm101p PF06420.7 KLO08518.1 - 2.3e-88 293.9 0.0 3.1e-88 293.5 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial genome maintenance MGM101 Spc97_Spc98 PF04130.8 KLO08519.1 - 9.6e-58 195.8 4.0 1.5e-57 195.2 2.8 1.3 1 0 0 1 1 1 1 Spc97 / Spc98 family VWA_2 PF13519.1 KLO08520.1 - 4.8e-07 30.0 0.1 1.1e-06 28.9 0.1 1.5 1 1 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.23 KLO08520.1 - 0.00017 21.3 0.0 0.023 14.4 0.0 2.5 1 1 0 1 1 1 1 von Willebrand factor type A domain PCI PF01399.22 KLO08521.1 - 2.2e-11 44.0 0.0 5.5e-11 42.7 0.0 1.7 1 0 0 1 1 1 1 PCI domain Thioredoxin_4 PF13462.1 KLO08522.1 - 8.7e-11 42.0 0.0 4e-10 39.9 0.0 1.8 1 1 0 1 1 1 1 Thioredoxin DSBA PF01323.15 KLO08522.1 - 0.021 14.3 0.0 0.15 11.5 0.0 2.0 2 0 0 2 2 2 0 DSBA-like thioredoxin domain GatB_N PF02934.10 KLO08523.1 - 3.6e-106 354.2 0.0 5.3e-106 353.6 0.0 1.2 1 0 0 1 1 1 1 GatB/GatE catalytic domain GatB_Yqey PF02637.13 KLO08523.1 - 3.4e-29 101.4 0.1 5.4e-29 100.8 0.1 1.3 1 0 0 1 1 1 1 GatB domain DPBB_1 PF03330.13 KLO08524.1 - 1.3e-06 28.3 0.1 2.5e-06 27.4 0.1 1.6 1 1 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Barwin PF00967.12 KLO08524.1 - 0.052 13.2 0.1 0.11 12.2 0.0 1.6 1 0 0 1 1 1 0 Barwin family WD40 PF00400.27 KLO08525.1 - 8e-76 247.4 31.0 9.1e-09 34.8 0.0 11.9 13 0 0 13 13 13 11 WD domain, G-beta repeat Utp12 PF04003.7 KLO08525.1 - 8.7e-17 61.0 1.3 1.6e-16 60.1 0.9 1.5 1 0 0 1 1 1 1 Dip2/Utp12 Family Nup160 PF11715.3 KLO08525.1 - 1.6e-07 29.9 13.4 0.0023 16.1 0.2 5.9 3 2 2 5 5 5 2 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 KLO08525.1 - 1.2e-06 27.5 10.7 0.024 13.3 0.1 5.1 2 1 2 5 5 5 4 Nup133 N terminal like Apc4_WD40 PF12894.2 KLO08525.1 - 6.4e-05 22.3 0.0 0.046 13.2 0.0 4.2 4 0 0 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain RNase_H2-Ydr279 PF09468.5 KLO08525.1 - 0.03 13.5 6.3 0.025 13.7 1.4 2.3 2 0 0 2 2 2 0 Ydr279p protein family (RNase H2 complex component) RAI16-like PF10257.4 KLO08525.1 - 0.033 13.1 0.2 0.056 12.3 0.1 1.3 1 0 0 1 1 1 0 Retinoic acid induced 16-like protein Peptidase_M18 PF02127.10 KLO08526.1 - 2.2e-149 497.6 0.0 2.5e-149 497.4 0.0 1.0 1 0 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) Peptidase_M42 PF05343.9 KLO08526.1 - 1.4e-05 24.0 0.0 0.002 16.9 0.1 2.3 2 0 0 2 2 2 2 M42 glutamyl aminopeptidase SKN1 PF03935.10 KLO08527.1 - 3e-180 599.6 4.8 3.7e-180 599.3 3.3 1.0 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) TFR_dimer PF04253.10 KLO08530.1 - 6.2e-15 54.8 0.2 9.9e-14 50.9 0.0 2.4 2 0 0 2 2 2 1 Transferrin receptor-like dimerisation domain Peptidase_M28 PF04389.12 KLO08530.1 - 1.1e-13 51.3 0.0 7.7e-13 48.5 0.0 2.2 1 1 0 1 1 1 1 Peptidase family M28 PA PF02225.17 KLO08530.1 - 4.2e-06 26.3 0.0 1e-05 25.1 0.0 1.6 1 0 0 1 1 1 1 PA domain ORC2 PF04084.9 KLO08531.1 - 1.3e-74 251.0 0.0 1.6e-74 250.7 0.0 1.1 1 0 0 1 1 1 1 Origin recognition complex subunit 2 DEAD PF00270.24 KLO08532.1 - 7.4e-19 67.8 0.0 1.4e-18 66.9 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KLO08532.1 - 9.7e-19 67.0 0.7 9.9e-18 63.7 0.0 3.2 5 0 0 5 5 5 1 Helicase conserved C-terminal domain ResIII PF04851.10 KLO08532.1 - 0.013 15.3 0.0 0.027 14.3 0.0 1.5 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit DASH_Spc19 PF08287.6 KLO08533.1 - 1.7e-16 60.1 0.7 2.4e-16 59.7 0.5 1.1 1 0 0 1 1 1 1 Spc19 Peptidase_M41 PF01434.13 KLO08533.1 - 0.022 14.2 0.1 0.027 13.9 0.0 1.1 1 0 0 1 1 1 0 Peptidase family M41 PilM PF07419.7 KLO08533.1 - 0.049 13.1 0.0 0.06 12.8 0.0 1.2 1 0 0 1 1 1 0 PilM GST_N_3 PF13417.1 KLO08534.1 - 3.7e-22 78.3 0.1 9e-22 77.0 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 KLO08534.1 - 2.5e-15 56.2 0.1 7.6e-15 54.6 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 KLO08534.1 - 2.3e-10 40.4 0.1 4.2e-10 39.6 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 KLO08534.1 - 1.1e-08 34.8 0.0 2e-08 34.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 KLO08534.1 - 7.9e-07 28.8 0.1 1.5e-06 27.9 0.1 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 KLO08534.1 - 6.1e-06 26.6 0.3 2.1e-05 24.9 0.2 1.9 1 1 1 2 2 2 1 Glutathione S-transferase, C-terminal domain DUF3621 PF12285.3 KLO08534.1 - 0.13 12.4 0.4 0.13 12.4 0.3 2.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3621) DUF2407 PF10302.4 KLO08535.1 - 1.5e-17 63.5 0.1 2.6e-17 62.7 0.1 1.4 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain DUF2407_C PF13373.1 KLO08535.1 - 7.2e-15 55.1 3.1 9.6e-13 48.2 2.1 2.3 1 1 0 1 1 1 1 DUF2407 C-terminal domain ubiquitin PF00240.18 KLO08535.1 - 3.8e-06 26.1 0.0 6.5e-06 25.4 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD_2 PF13881.1 KLO08535.1 - 0.12 12.2 0.1 0.7 9.7 0.0 2.2 2 1 0 2 2 2 0 Ubiquitin-2 like Rad60 SUMO-like adh_short PF00106.20 KLO08536.1 - 2.2e-16 60.2 1.7 3.2e-16 59.7 1.2 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KLO08536.1 - 2.3e-07 30.8 0.2 3.1e-07 30.4 0.1 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase YjeF_N PF03853.10 KLO08536.1 - 0.00013 21.6 0.2 0.0021 17.6 0.1 2.1 2 0 0 2 2 2 1 YjeF-related protein N-terminus KR PF08659.5 KLO08536.1 - 0.0023 17.6 0.3 0.007 16.0 0.2 1.7 1 1 0 1 1 1 1 KR domain 3HCDH_N PF02737.13 KLO08536.1 - 0.015 14.9 0.4 0.03 13.9 0.3 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DUF1598 PF07643.6 KLO08536.1 - 0.14 12.2 0.1 1.2 9.1 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1598) NmrA PF05368.8 KLO08536.1 - 0.32 10.1 2.3 0.23 10.6 0.2 1.7 2 0 0 2 2 2 0 NmrA-like family PBP_sp32 PF07222.7 KLO08537.1 - 0.6 9.2 4.8 0.78 8.8 3.3 1.1 1 0 0 1 1 1 0 Proacrosin binding protein sp32 NYD-SP12_N PF15015.1 KLO08537.1 - 1.6 6.8 7.8 0.2 9.8 2.3 1.6 1 1 1 2 2 2 0 Spermatogenesis-associated, N-terminal DUF2413 PF10310.4 KLO08537.1 - 5.6 5.6 13.5 6.7 5.4 9.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) TSP9 PF11493.3 KLO08540.1 - 7.2 7.2 7.6 1 9.9 2.0 2.0 3 0 0 3 3 3 0 Thylakoid soluble phosphoprotein TSP9 Kin17_mid PF10357.4 KLO08541.1 - 4.3e-48 162.1 0.6 4.3e-48 162.1 0.4 1.8 2 0 0 2 2 2 1 Domain of Kin17 curved DNA-binding protein zf-met PF12874.2 KLO08541.1 - 0.00057 19.9 6.2 0.0014 18.7 4.3 1.7 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 KLO08541.1 - 0.0054 16.8 5.1 0.013 15.5 3.5 1.7 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.2 KLO08541.1 - 0.02 14.9 0.5 0.02 14.9 0.4 2.1 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) AKAP95 PF04988.7 KLO08541.1 - 0.54 10.0 5.1 0.23 11.2 1.2 2.1 2 0 0 2 2 2 0 A-kinase anchoring protein 95 (AKAP95) zf-CCCH PF00642.19 KLO08542.1 - 8.1e-14 50.9 31.4 3.1e-06 26.7 1.5 4.6 4 1 0 4 4 4 4 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Macoilin PF09726.4 KLO08542.1 - 2.3 6.3 7.6 4.1 5.5 5.2 1.3 1 0 0 1 1 1 0 Transmembrane protein zf-RING_2 PF13639.1 KLO08543.1 - 6.3e-14 51.5 3.7 1.4e-13 50.4 2.6 1.6 1 0 0 1 1 1 1 Ring finger domain PA PF02225.17 KLO08543.1 - 7.7e-13 48.0 0.0 1.6e-12 46.9 0.0 1.6 1 0 0 1 1 1 1 PA domain zf-C3HC4_2 PF13923.1 KLO08543.1 - 1.7e-06 27.9 3.8 3.7e-06 26.8 2.6 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KLO08543.1 - 1.7e-06 27.6 1.8 3.1e-06 26.7 1.3 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.2 KLO08543.1 - 6.7e-06 26.1 4.0 1.5e-05 24.9 2.7 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_3 PF13920.1 KLO08543.1 - 7.7e-06 25.4 1.6 1.6e-05 24.4 1.1 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KLO08543.1 - 0.00012 21.6 2.8 0.00022 20.7 1.9 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 KLO08543.1 - 0.018 14.8 3.3 0.062 13.1 2.3 1.9 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger FANCL_C PF11793.3 KLO08543.1 - 0.72 9.8 4.2 5.1 7.1 2.9 2.3 1 1 0 1 1 1 0 FANCL C-terminal domain Heme_oxygenase PF01126.15 KLO08544.1 - 1.1e-37 129.6 0.0 3.6e-37 127.9 0.0 1.8 1 1 0 1 1 1 1 Heme oxygenase CBFD_NFYB_HMF PF00808.18 KLO08547.1 - 5.5e-21 74.3 0.8 7.5e-21 73.9 0.6 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 KLO08547.1 - 9.6e-10 38.4 0.0 1.4e-09 37.9 0.0 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-X PF09415.5 KLO08547.1 - 0.0071 16.1 0.0 0.011 15.5 0.0 1.3 1 0 0 1 1 1 1 CENP-S associating Centromere protein X TAF PF02969.12 KLO08547.1 - 0.057 13.3 0.2 0.1 12.5 0.1 1.4 1 0 0 1 1 1 0 TATA box binding protein associated factor (TAF) Heme_oxygenase PF01126.15 KLO08548.1 - 9.1e-36 123.3 0.0 1.3e-35 122.8 0.0 1.2 1 0 0 1 1 1 1 Heme oxygenase RicinB_lectin_2 PF14200.1 KLO08549.1 - 0.00064 20.0 0.1 0.082 13.2 0.0 2.1 2 0 0 2 2 2 2 Ricin-type beta-trefoil lectin domain-like Ricin_B_lectin PF00652.17 KLO08549.1 - 0.049 13.6 0.0 0.18 11.8 0.0 1.7 1 1 0 1 1 1 0 Ricin-type beta-trefoil lectin domain Asp PF00026.18 KLO08550.1 - 4.1e-20 72.2 2.2 7.1e-18 64.9 1.5 2.2 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 KLO08550.1 - 0.0056 16.6 0.7 0.19 11.6 0.5 2.6 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 KLO08550.1 - 0.0065 16.9 1.6 0.014 15.8 0.2 2.3 2 1 0 2 2 2 1 Aspartyl protease TMEM52 PF14979.1 KLO08550.1 - 0.029 14.2 0.0 0.058 13.3 0.0 1.4 1 0 0 1 1 1 0 Transmembrane 52 DUF4098 PF13345.1 KLO08550.1 - 1.8 8.5 8.1 6.6 6.7 2.0 3.6 2 1 1 3 3 3 0 Domain of unknown function (DUF4098) Dynactin_p62 PF05502.8 KLO08551.1 - 6.4e-81 272.5 12.0 8e-51 173.2 4.5 2.1 1 1 0 2 2 2 2 Dynactin p62 family TAF PF02969.12 KLO08552.1 - 2.8e-23 81.6 0.2 5e-23 80.8 0.2 1.4 1 0 0 1 1 1 1 TATA box binding protein associated factor (TAF) DUF1546 PF07571.8 KLO08552.1 - 1.6e-16 60.1 0.0 4e-16 58.9 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1546) Histone PF00125.19 KLO08552.1 - 0.00013 21.9 0.0 0.00066 19.7 0.5 1.8 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 HEAT_EZ PF13513.1 KLO08552.1 - 0.015 15.7 2.0 16 6.1 0.0 4.3 3 1 1 4 4 4 0 HEAT-like repeat TFIID-31kDa PF02291.10 KLO08552.1 - 0.16 11.7 0.1 0.36 10.6 0.0 1.5 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Ribosomal_L10 PF00466.15 KLO08553.1 - 9.1e-17 60.8 0.0 1.3e-16 60.3 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L10 DinI PF06183.8 KLO08553.1 - 0.017 15.0 0.2 0.031 14.2 0.2 1.4 1 0 0 1 1 1 0 DinI-like family RrnaAD PF00398.15 KLO08554.1 - 3.5e-54 183.6 0.0 4.5e-54 183.2 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_26 PF13659.1 KLO08554.1 - 3.1e-10 40.0 0.0 5.1e-10 39.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KLO08554.1 - 3e-06 27.7 0.0 5e-06 27.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KLO08554.1 - 1.4e-05 24.5 0.0 2.3e-05 23.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_2 PF00891.13 KLO08554.1 - 4.6e-05 22.7 0.0 6.9e-05 22.1 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_31 PF13847.1 KLO08554.1 - 0.00011 21.8 0.0 0.00026 20.6 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 KLO08554.1 - 0.00022 21.0 0.0 0.00034 20.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 KLO08554.1 - 0.00037 20.1 0.0 0.00061 19.3 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) CMAS PF02353.15 KLO08554.1 - 0.00066 18.8 0.0 0.0013 17.9 0.0 1.4 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_12 PF08242.7 KLO08554.1 - 0.001 19.5 0.0 0.0021 18.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain NodS PF05401.6 KLO08554.1 - 0.013 14.9 0.0 0.019 14.3 0.0 1.3 1 0 0 1 1 1 0 Nodulation protein S (NodS) Ubie_methyltran PF01209.13 KLO08554.1 - 0.041 13.0 0.0 0.065 12.3 0.0 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_28 PF02636.12 KLO08554.1 - 0.083 12.2 0.0 0.13 11.6 0.0 1.3 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase DREV PF05219.7 KLO08554.1 - 0.13 11.1 0.0 0.2 10.5 0.0 1.2 1 0 0 1 1 1 0 DREV methyltransferase HEAT_2 PF13646.1 KLO08555.1 - 5.8e-45 151.4 10.2 2.7e-15 56.4 0.2 4.0 2 2 3 5 5 5 5 HEAT repeats HEAT_PBS PF03130.11 KLO08555.1 - 3.9e-24 82.6 0.1 0.00069 19.8 0.0 7.0 7 0 0 7 7 7 4 PBS lyase HEAT-like repeat HEAT PF02985.17 KLO08555.1 - 5.9e-10 38.3 0.2 0.11 12.6 0.0 5.2 5 0 0 5 5 5 2 HEAT repeat HEAT_EZ PF13513.1 KLO08555.1 - 3.3e-09 36.9 2.6 0.032 14.7 0.1 5.1 4 2 2 6 6 6 2 HEAT-like repeat Arm PF00514.18 KLO08555.1 - 1.3e-05 24.8 0.1 0.015 15.0 0.0 2.9 2 0 0 2 2 2 2 Armadillo/beta-catenin-like repeat DUF1546 PF07571.8 KLO08555.1 - 0.012 15.6 0.0 0.44 10.7 0.0 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF1546) DUF3719 PF12516.3 KLO08557.1 - 0.24 10.9 3.8 1.9 8.1 0.2 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3719) DUF4047 PF13256.1 KLO08557.1 - 0.95 9.4 7.6 6.3 6.7 3.2 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4047) APG6 PF04111.7 KLO08557.1 - 1.5 7.7 8.7 3 6.8 6.0 1.5 1 0 0 1 1 1 0 Autophagy protein Apg6 FUSC PF04632.7 KLO08557.1 - 1.6 7.0 7.8 2.2 6.5 5.4 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family IncA PF04156.9 KLO08557.1 - 2.5 7.6 9.5 6.1 6.3 6.6 1.6 1 0 0 1 1 1 0 IncA protein DivIC PF04977.10 KLO08557.1 - 4.5 6.8 9.6 0.66 9.5 0.7 2.5 1 1 0 2 2 2 0 Septum formation initiator DUF1793 PF08760.6 KLO08558.1 - 7.6e-28 97.5 0.0 1.2e-27 96.8 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1793) Bac_rhamnosid PF05592.6 KLO08558.1 - 0.0027 15.9 0.0 0.0043 15.3 0.0 1.2 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase p450 PF00067.17 KLO08559.1 - 3.8e-69 233.4 0.0 4.3e-69 233.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Acetyltransf_1 PF00583.19 KLO08564.1 - 5.9e-06 26.2 0.0 0.00014 21.8 0.0 2.5 2 1 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 KLO08564.1 - 0.0042 17.2 0.0 0.012 15.8 0.0 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain DUF716 PF04819.7 KLO08565.1 - 1.2 8.5 8.8 4.4 6.7 0.2 2.8 3 0 0 3 3 3 0 Family of unknown function (DUF716) Exo_endo_phos PF03372.18 KLO08568.1 - 2.6e-13 50.5 0.2 3.8e-13 49.9 0.1 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family RVT_1 PF00078.22 KLO08569.1 - 0.012 14.9 0.0 0.012 14.9 0.0 1.1 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) zf-RVT PF13966.1 KLO08571.1 - 1e-06 28.9 0.9 4.9e-06 26.7 0.8 2.0 2 0 0 2 2 2 1 zinc-binding in reverse transcriptase HypA PF01155.14 KLO08571.1 - 0.012 15.2 0.1 0.04 13.6 0.1 1.8 2 0 0 2 2 2 0 Hydrogenase expression/synthesis hypA family SIR2 PF02146.12 KLO08573.1 - 9.1e-29 100.4 0.0 1.2e-28 100.0 0.0 1.1 1 0 0 1 1 1 1 Sir2 family SIR2 PF02146.12 KLO08574.1 - 3.1e-23 82.4 0.0 4.5e-23 81.8 0.0 1.2 1 0 0 1 1 1 1 Sir2 family DUF1793 PF08760.6 KLO08575.1 - 8.3e-31 107.1 0.0 1.5e-30 106.3 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1793) RRM_1 PF00076.17 KLO08576.1 - 9.9e-35 118.0 0.2 9e-18 63.6 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KLO08576.1 - 2.8e-27 94.5 0.1 8.6e-15 54.4 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KLO08576.1 - 3.7e-12 45.9 0.4 4.5e-07 29.6 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Glyco_hydro_85 PF03644.8 KLO08577.1 - 2.1e-77 260.2 0.0 2.9e-77 259.8 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 85 Nop14 PF04147.7 KLO08578.1 - 0.0071 14.3 5.5 0.013 13.4 3.8 1.4 1 0 0 1 1 1 1 Nop14-like family SH3_9 PF14604.1 KLO08579.1 - 3.1e-05 23.4 0.0 6e-05 22.5 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 KLO08579.1 - 0.00083 18.7 0.0 0.0015 17.9 0.0 1.4 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 KLO08579.1 - 0.045 13.2 0.0 0.082 12.4 0.0 1.4 1 0 0 1 1 1 0 Variant SH3 domain Suf PF05843.9 KLO08580.1 - 1.6e-66 224.9 10.3 1.6e-65 221.6 0.0 4.4 3 1 2 5 5 5 1 Suppressor of forked protein (Suf) TPR_14 PF13428.1 KLO08580.1 - 9.4e-09 35.1 4.7 0.013 16.0 0.0 6.6 6 1 1 7 7 7 2 Tetratricopeptide repeat TPR_16 PF13432.1 KLO08580.1 - 2.8e-06 27.8 14.8 0.0048 17.5 0.3 5.3 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_19 PF14559.1 KLO08580.1 - 3.4e-05 24.0 5.6 0.66 10.3 0.1 4.7 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_11 PF13414.1 KLO08580.1 - 0.0062 16.1 3.5 0.42 10.3 0.0 3.3 3 0 0 3 3 3 2 TPR repeat TPR_6 PF13174.1 KLO08580.1 - 0.012 15.9 6.8 5.2 7.7 0.0 5.3 5 0 0 5 5 5 0 Tetratricopeptide repeat Hydrolase_6 PF13344.1 KLO08581.1 - 6.8e-14 51.5 0.0 1.1e-13 50.8 0.0 1.3 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 KLO08581.1 - 7e-10 38.4 0.0 2.5e-09 36.6 0.0 1.9 2 0 0 2 2 2 1 HAD-hyrolase-like Dioxygenase_C PF00775.16 KLO08582.1 - 1.3e-13 50.5 0.3 3.8e-13 49.1 0.2 1.7 1 1 0 1 1 1 1 Dioxygenase WD40 PF00400.27 KLO08583.1 - 3.5e-43 143.9 21.9 9.3e-09 34.8 0.0 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 KLO08583.1 - 2 6.4 6.2 11 4.0 1.7 2.6 2 1 1 3 3 3 0 Nucleoporin Nup120/160 DUF4047 PF13256.1 KLO08584.1 - 0.058 13.3 0.7 0.15 12.0 0.5 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4047) Sec23_trunk PF04811.10 KLO08585.1 - 4.3e-44 150.7 0.0 7.5e-44 149.9 0.0 1.4 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.10 KLO08585.1 - 4.4e-22 77.4 1.1 7.6e-22 76.7 0.8 1.4 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Sec23_BS PF08033.7 KLO08585.1 - 2.1e-15 56.9 0.0 4.1e-15 56.0 0.0 1.5 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.10 KLO08585.1 - 6.3e-15 54.4 4.9 1.5e-14 53.2 3.4 1.7 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.17 KLO08585.1 - 0.00062 19.4 0.0 0.0027 17.3 0.0 2.0 2 0 0 2 2 2 1 Gelsolin repeat AAA PF00004.24 KLO08586.1 - 2e-46 157.4 0.0 8.1e-42 142.5 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 KLO08586.1 - 2.4e-07 30.9 0.0 1.1e-06 28.7 0.0 2.1 1 0 0 1 1 1 1 AAA ATPase domain AAA_2 PF07724.9 KLO08586.1 - 3.2e-05 23.8 0.0 8.3e-05 22.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.1 KLO08586.1 - 6.3e-05 23.1 0.1 0.0044 17.1 0.1 2.8 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.12 KLO08586.1 - 6.4e-05 22.4 0.0 0.00016 21.1 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_19 PF13245.1 KLO08586.1 - 0.0011 18.6 0.0 0.0042 16.8 0.0 2.0 1 0 0 1 1 1 1 Part of AAA domain AAA_5 PF07728.9 KLO08586.1 - 0.003 17.2 0.0 0.015 15.0 0.0 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_17 PF13207.1 KLO08586.1 - 0.0044 17.8 0.1 0.03 15.1 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.1 KLO08586.1 - 0.0086 15.9 1.8 0.017 15.0 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.1 KLO08586.1 - 0.0096 15.3 0.0 0.035 13.5 0.0 2.0 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 KLO08586.1 - 0.039 14.2 1.7 0.073 13.3 0.0 2.4 2 0 0 2 2 1 0 AAA domain PhoH PF02562.11 KLO08586.1 - 0.061 12.5 0.0 0.11 11.6 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein Mg_chelatase PF01078.16 KLO08586.1 - 0.068 12.3 0.1 0.12 11.5 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI TIP49 PF06068.8 KLO08586.1 - 0.077 11.7 0.0 0.13 11.0 0.0 1.2 1 0 0 1 1 1 0 TIP49 C-terminus RNA_helicase PF00910.17 KLO08586.1 - 0.11 12.6 0.0 0.26 11.4 0.0 1.6 1 0 0 1 1 1 0 RNA helicase Bromodomain PF00439.20 KLO08586.1 - 0.14 12.0 0.0 0.31 10.9 0.0 1.5 1 0 0 1 1 1 0 Bromodomain Parvo_NS1 PF01057.12 KLO08586.1 - 0.22 10.3 0.0 0.41 9.4 0.0 1.4 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 PIF1 PF05970.9 KLO08586.1 - 0.37 9.6 0.0 0.64 8.8 0.0 1.3 1 0 0 1 1 1 0 PIF1-like helicase DUF1793 PF08760.6 KLO08587.1 - 2.2e-13 50.4 0.0 3.7e-13 49.6 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1793) GBA2_N PF12215.3 KLO08587.1 - 0.02 14.0 0.3 0.039 13.1 0.2 1.5 1 0 0 1 1 1 0 beta-Glucocerebrosidase 2 N terminal K167R PF08065.7 KLO08589.1 - 0.017 15.1 2.7 1.6 8.8 0.3 2.5 2 1 1 3 3 3 0 K167R (NUC007) repeat SMI1_KNR4 PF09346.5 KLO08589.1 - 0.14 12.2 0.0 0.15 12.0 0.0 1.1 1 0 0 1 1 1 0 SMI1 / KNR4 family (SUKH-1) Pap_E4 PF02711.9 KLO08589.1 - 3.8 8.3 6.8 0.49 11.2 1.0 1.9 2 0 0 2 2 2 0 E4 protein DUF1793 PF08760.6 KLO08590.1 - 5.8e-12 45.8 0.0 1e-11 44.9 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1793) Syndecan PF01034.15 KLO08591.1 - 0.016 14.8 0.0 0.032 13.8 0.0 1.4 1 0 0 1 1 1 0 Syndecan domain DUF3494 PF11999.3 KLO08591.1 - 0.028 14.0 1.1 0.051 13.2 0.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3494) EssA PF10661.4 KLO08591.1 - 0.11 12.1 0.0 0.2 11.3 0.0 1.4 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein EssA VPEP PF07589.6 KLO08591.1 - 0.22 11.4 1.9 0.46 10.4 1.3 1.6 1 0 0 1 1 1 0 PEP-CTERM motif Pkinase PF00069.20 KLO08592.1 - 6.5e-12 45.1 0.0 9.3e-11 41.3 0.0 2.0 1 1 1 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 KLO08592.1 - 0.0014 17.8 0.0 0.003 16.6 0.0 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase DUF4426 PF14467.1 KLO08592.1 - 0.058 13.1 0.0 0.1 12.4 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4426) Kelch_3 PF13415.1 KLO08594.1 - 3e-32 110.0 16.3 8.5e-11 41.7 0.0 5.6 6 0 0 6 6 6 5 Galactose oxidase, central domain Kelch_1 PF01344.20 KLO08594.1 - 1.5e-31 107.7 15.8 9e-10 37.9 0.6 5.1 5 0 0 5 5 5 5 Kelch motif Kelch_5 PF13854.1 KLO08594.1 - 8.6e-28 95.8 13.9 5.4e-09 35.8 0.1 5.3 5 0 0 5 5 5 5 Kelch motif Kelch_4 PF13418.1 KLO08594.1 - 1.6e-27 94.9 22.1 2.9e-11 42.9 0.3 5.4 4 2 1 5 5 5 5 Galactose oxidase, central domain Kelch_6 PF13964.1 KLO08594.1 - 3.8e-26 90.1 12.9 1.6e-09 37.5 0.4 5.1 4 1 1 5 5 5 5 Kelch motif Kelch_2 PF07646.10 KLO08594.1 - 6.5e-20 70.0 17.9 1.5e-05 24.5 0.1 5.6 5 1 0 5 5 5 5 Kelch motif RAG2 PF03089.9 KLO08594.1 - 3.6e-07 29.2 2.3 0.016 13.9 0.0 4.2 3 2 2 5 5 5 3 Recombination activating protein 2 TMEM52 PF14979.1 KLO08595.1 - 0.17 11.7 0.0 0.3 10.9 0.0 1.3 1 0 0 1 1 1 0 Transmembrane 52 SapC PF07277.6 KLO08599.1 - 0.0049 16.2 0.0 0.0088 15.3 0.0 1.3 1 0 0 1 1 1 1 SapC DUF2353 PF09789.4 KLO08600.1 - 0.012 14.9 3.6 0.021 14.0 2.5 1.4 1 0 0 1 1 1 0 Uncharacterized coiled-coil protein (DUF2353) Kelch_3 PF13415.1 KLO08605.1 - 1.3e-40 136.6 7.4 6.6e-11 42.0 0.3 6.6 6 0 0 6 6 6 5 Galactose oxidase, central domain Kelch_4 PF13418.1 KLO08605.1 - 1.5e-36 123.8 15.6 8.3e-11 41.4 0.9 7.1 7 1 0 7 7 7 6 Galactose oxidase, central domain Kelch_1 PF01344.20 KLO08605.1 - 1.7e-32 110.7 1.7 4.6e-08 32.4 0.9 6.3 6 0 0 6 6 6 5 Kelch motif Kelch_5 PF13854.1 KLO08605.1 - 1.6e-30 104.5 3.7 2.7e-07 30.4 0.1 6.4 6 0 0 6 6 6 5 Kelch motif Kelch_6 PF13964.1 KLO08605.1 - 8.1e-30 101.7 4.3 2.9e-09 36.6 0.5 6.5 4 1 2 6 6 6 6 Kelch motif Kelch_2 PF07646.10 KLO08605.1 - 1.3e-15 56.4 14.7 0.0076 15.9 0.4 7.1 6 2 0 6 6 6 5 Kelch motif RAG2 PF03089.9 KLO08605.1 - 6.5e-06 25.0 0.7 0.087 11.5 0.0 4.3 2 1 2 4 4 4 2 Recombination activating protein 2 DDE_Tnp_4 PF13359.1 KLO08611.1 - 0.00066 19.3 0.1 0.0019 17.8 0.1 1.7 2 0 0 2 2 2 1 DDE superfamily endonuclease DDE_Tnp_4 PF13359.1 KLO08612.1 - 6.5e-10 38.8 0.0 7.3e-10 38.6 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease Myb_DNA-bind_4 PF13837.1 KLO08613.1 - 0.013 15.5 2.3 0.018 15.1 0.0 2.2 2 0 0 2 2 2 0 Myb/SANT-like DNA-binding domain Nnf1 PF03980.9 KLO08615.1 - 0.088 12.8 0.0 0.14 12.1 0.0 1.3 1 0 0 1 1 1 0 Nnf1 GCOM2 PF15328.1 KLO08616.1 - 0.0014 18.3 0.9 0.034 13.8 0.0 2.5 2 1 1 3 3 3 2 Putative GRINL1B complex locus protein 2 EIF4E-T PF10477.4 KLO08620.1 - 0.0055 15.5 5.0 0.0075 15.1 3.5 1.2 1 0 0 1 1 1 1 Nucleocytoplasmic shuttling protein for mRNA cap-binding EIF4E MULE PF10551.4 KLO08622.1 - 5.4e-09 36.0 0.0 1.3e-08 34.8 0.0 1.6 1 0 0 1 1 1 1 MULE transposase domain Transposase_mut PF00872.13 KLO08622.1 - 0.0038 15.8 0.0 0.0082 14.7 0.0 1.5 1 0 0 1 1 1 1 Transposase, Mutator family SWIM PF04434.12 KLO08623.1 - 0.00031 20.1 0.9 0.00052 19.4 0.1 1.7 2 0 0 2 2 2 1 SWIM zinc finger TerB PF05099.8 KLO08624.1 - 0.13 11.9 1.5 2.6 7.7 0.0 2.3 2 0 0 2 2 2 0 Tellurite resistance protein TerB Tetraspannin PF00335.15 KLO08624.1 - 0.45 9.7 8.6 1.2 8.3 5.9 1.6 1 1 0 1 1 1 0 Tetraspanin family GMC_oxred_N PF00732.14 KLO08626.1 - 2.1e-54 184.7 0.0 2.6e-54 184.4 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 KLO08626.1 - 6.4e-29 101.0 0.0 1e-28 100.4 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 KLO08626.1 - 4.9e-08 32.2 0.1 1.6e-05 23.9 0.0 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KLO08626.1 - 8.2e-06 25.7 0.3 5.3e-05 23.1 0.1 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 KLO08626.1 - 0.0005 19.0 0.1 0.0007 18.6 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_binding_2 PF00890.19 KLO08626.1 - 0.001 18.0 0.5 0.0027 16.6 0.1 1.8 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.9 KLO08626.1 - 0.013 13.9 0.0 0.023 13.1 0.0 1.3 1 0 0 1 1 1 0 HI0933-like protein Pyr_redox_2 PF07992.9 KLO08626.1 - 0.015 15.1 0.0 0.054 13.3 0.0 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 KLO08626.1 - 0.015 15.0 0.1 0.39 10.4 0.0 2.5 2 0 0 2 2 2 0 FAD-NAD(P)-binding Pyr_redox_3 PF13738.1 KLO08626.1 - 0.028 14.4 0.0 0.56 10.2 0.0 2.6 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 KLO08626.1 - 0.035 13.1 0.1 0.079 12.0 0.1 1.5 1 0 0 1 1 1 0 Thi4 family K_oxygenase PF13434.1 KLO08626.1 - 0.084 11.7 0.0 0.12 11.2 0.0 1.2 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) Pkinase_Tyr PF07714.12 KLO08627.1 - 3.4e-29 101.7 0.0 6.1e-29 100.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 KLO08627.1 - 1.5e-28 99.6 0.0 2.5e-28 98.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.18 KLO08627.1 - 0.004 16.9 0.0 0.0089 15.7 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.1 KLO08627.1 - 0.027 13.4 0.0 0.05 12.5 0.0 1.3 1 0 0 1 1 1 0 Kinase-like DUF3731 PF12531.3 KLO08627.1 - 0.083 12.3 0.0 0.16 11.4 0.0 1.5 1 0 0 1 1 1 0 DNA-K related protein Pkinase PF00069.20 KLO08628.1 - 2.1e-09 36.9 0.0 1.6e-08 34.0 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KLO08628.1 - 0.012 14.6 0.0 0.019 14.0 0.0 1.3 1 0 0 1 1 1 0 Protein tyrosine kinase DUF2273 PF10031.4 KLO08629.1 - 0.059 12.9 0.9 0.1 12.2 0.7 1.3 1 0 0 1 1 1 0 Small integral membrane protein (DUF2273) Pkinase PF00069.20 KLO08630.1 - 1.6e-38 132.3 0.0 2.3e-38 131.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KLO08630.1 - 4.7e-30 104.5 0.0 7.6e-30 103.8 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 KLO08630.1 - 0.0014 17.7 0.0 0.0023 17.0 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family DUF3529 PF12046.3 KLO08630.1 - 0.0023 16.9 0.0 0.0053 15.8 0.0 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF3529) YrbL-PhoP_reg PF10707.4 KLO08630.1 - 0.02 14.2 0.0 0.044 13.1 0.0 1.5 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL Chitin_synth_2 PF03142.10 KLO08631.1 - 3.9e-241 801.0 0.0 5.3e-241 800.6 0.0 1.1 1 0 0 1 1 1 1 Chitin synthase Myosin_head PF00063.16 KLO08631.1 - 8.6e-123 410.7 0.0 1.7e-122 409.7 0.0 1.4 1 0 0 1 1 1 1 Myosin head (motor domain) Cyt-b5 PF00173.23 KLO08631.1 - 2.9e-20 71.8 0.0 2e-10 40.3 0.0 3.0 1 1 1 2 2 2 2 Cytochrome b5-like Heme/Steroid binding domain Glyco_tranf_2_3 PF13641.1 KLO08631.1 - 1e-17 64.7 0.0 9.3e-14 51.7 0.0 2.5 2 0 0 2 2 2 2 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.1 KLO08631.1 - 1.5e-15 57.4 5.9 1.5e-15 57.4 4.1 2.3 2 1 0 2 2 2 1 Glycosyl transferase family group 2 DEK_C PF08766.6 KLO08631.1 - 3e-13 49.3 0.3 2.7e-12 46.2 0.3 2.6 2 0 0 2 2 2 1 DEK C terminal domain Glycos_transf_2 PF00535.21 KLO08631.1 - 1.5e-08 34.4 0.0 1.9e-05 24.4 0.0 2.6 2 0 0 2 2 2 2 Glycosyl transferase family 2 Glyco_transf_21 PF13506.1 KLO08631.1 - 0.00025 20.3 0.0 0.002 17.4 0.0 2.1 2 0 0 2 2 2 1 Glycosyl transferase family 21 Pkinase PF00069.20 KLO08633.1 - 1.5e-37 129.2 0.0 5.5e-37 127.3 0.0 1.8 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 KLO08633.1 - 5.8e-35 120.5 0.0 1.6e-34 119.1 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.18 KLO08633.1 - 0.008 15.9 0.0 0.015 15.0 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.17 KLO08633.1 - 0.097 12.0 0.0 0.79 9.0 0.0 2.2 2 0 0 2 2 2 0 RIO1 family Pkinase PF00069.20 KLO08634.1 - 4.2e-08 32.6 0.0 1.1e-07 31.3 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KLO08634.1 - 0.025 13.6 0.0 0.054 12.5 0.0 1.6 2 0 0 2 2 2 0 Protein tyrosine kinase Pkinase PF00069.20 KLO08635.1 - 1.7e-06 27.3 0.0 3.1e-06 26.5 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Dynamin_M PF01031.15 KLO08635.1 - 0.19 10.4 0.0 0.31 9.7 0.0 1.2 1 0 0 1 1 1 0 Dynamin central region Pkinase_Tyr PF07714.12 KLO08636.1 - 1.4e-39 135.7 0.0 5.5e-39 133.8 0.0 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase PF00069.20 KLO08636.1 - 5.5e-39 133.8 0.0 1.2e-38 132.8 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.18 KLO08636.1 - 0.0013 18.5 0.2 0.0028 17.4 0.0 1.6 2 0 0 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.17 KLO08636.1 - 0.065 12.5 0.0 0.32 10.3 0.0 2.2 2 0 0 2 2 2 0 RIO1 family UDPGT PF00201.13 KLO08636.1 - 0.11 11.0 0.2 0.21 10.1 0.1 1.4 1 0 0 1 1 1 0 UDP-glucoronosyl and UDP-glucosyl transferase Pkinase PF00069.20 KLO08637.1 - 1.5e-10 40.6 0.0 3e-08 33.1 0.0 2.4 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 KLO08637.1 - 0.062 12.3 0.0 0.087 11.8 0.0 1.2 1 0 0 1 1 1 0 Protein tyrosine kinase APH PF01636.18 KLO08637.1 - 0.077 12.7 0.0 0.15 11.7 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pkinase PF00069.20 KLO08638.1 - 4.3e-34 117.8 0.0 5.5e-34 117.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KLO08638.1 - 4.7e-29 101.2 0.0 8e-29 100.4 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase YrbL-PhoP_reg PF10707.4 KLO08638.1 - 0.0011 18.3 0.0 0.0018 17.6 0.0 1.3 1 0 0 1 1 1 1 PhoP regulatory network protein YrbL Kdo PF06293.9 KLO08638.1 - 0.0012 17.9 0.0 0.0022 17.0 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KLO08638.1 - 0.14 11.9 1.0 0.36 10.5 0.1 1.9 2 0 0 2 2 2 0 Phosphotransferase enzyme family Pkinase PF00069.20 KLO08639.1 - 0.00047 19.3 0.0 0.00076 18.6 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KLO08639.1 - 0.0012 17.9 0.0 0.0024 17.0 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Coatomer_WDAD PF04053.9 KLO08641.1 - 3.4e-150 500.6 0.0 6.2e-150 499.8 0.0 1.4 1 0 0 1 1 1 1 Coatomer WD associated region WD40 PF00400.27 KLO08641.1 - 3.5e-55 182.0 11.3 9.6e-12 44.3 0.0 8.5 9 0 0 9 9 9 6 WD domain, G-beta repeat BBS2_Mid PF14783.1 KLO08641.1 - 8.5e-05 22.2 0.0 4.4 7.1 0.0 4.3 5 1 0 5 5 5 2 Ciliary BBSome complex subunit 2, middle region Nup160 PF11715.3 KLO08641.1 - 0.0053 14.9 0.8 0.32 9.0 0.0 2.7 1 1 0 2 2 2 2 Nucleoporin Nup120/160 Abhydrolase_6 PF12697.2 KLO08642.1 - 2.1e-35 122.6 0.8 3e-35 122.1 0.6 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KLO08642.1 - 4.8e-21 75.0 0.2 8.7e-21 74.2 0.1 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KLO08642.1 - 2.2e-20 73.2 1.1 2.9e-18 66.2 0.8 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_4 PF08386.5 KLO08642.1 - 6.9e-08 32.3 0.0 1.1e-07 31.6 0.0 1.3 1 0 0 1 1 1 1 TAP-like protein Hydrolase_4 PF12146.3 KLO08642.1 - 5.2e-06 26.2 0.0 1e-05 25.3 0.0 1.5 1 0 0 1 1 1 1 Putative lysophospholipase DLH PF01738.13 KLO08642.1 - 9.6e-06 25.0 0.0 0.0026 17.0 0.1 2.9 2 1 0 2 2 2 1 Dienelactone hydrolase family DUF2048 PF09752.4 KLO08642.1 - 0.0016 17.3 0.2 0.39 9.5 0.2 2.2 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2048) Peptidase_S9 PF00326.16 KLO08642.1 - 0.0081 15.3 0.4 0.37 9.9 0.0 2.5 2 1 0 2 2 2 1 Prolyl oligopeptidase family Peptidase_S28 PF05577.7 KLO08642.1 - 0.044 12.3 0.1 0.063 11.8 0.1 1.2 1 0 0 1 1 1 0 Serine carboxypeptidase S28 Esterase_phd PF10503.4 KLO08642.1 - 0.095 11.9 0.2 0.27 10.4 0.3 1.5 2 0 0 2 2 2 0 Esterase PHB depolymerase DUF2974 PF11187.3 KLO08642.1 - 0.1 11.9 0.1 0.17 11.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) DUF2416 PF10315.4 KLO08644.1 - 4.9e-15 55.7 0.3 6.1e-15 55.4 0.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2416) NUDIX PF00293.23 KLO08645.1 - 2.2e-14 53.2 0.0 3.5e-14 52.5 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain TAF4 PF05236.9 KLO08645.1 - 0.99 8.6 3.5 2 7.6 0.0 2.1 2 0 0 2 2 2 0 Transcription initiation factor TFIID component TAF4 family Pkinase PF00069.20 KLO08646.1 - 4.8e-22 78.3 0.0 5.6e-22 78.1 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KLO08646.1 - 6e-17 61.5 0.0 6.9e-17 61.3 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 KLO08646.1 - 0.00026 20.1 0.0 0.00041 19.4 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.20 KLO08647.1 - 0.00091 18.4 0.0 0.0015 17.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KLO08647.1 - 0.013 14.5 0.0 0.058 12.4 0.0 1.8 1 1 0 1 1 1 0 Protein tyrosine kinase Pkinase PF00069.20 KLO08648.1 - 4.8e-31 107.8 0.0 6.4e-31 107.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KLO08648.1 - 1.5e-26 93.0 0.0 4.8e-26 91.3 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase YrbL-PhoP_reg PF10707.4 KLO08648.1 - 3.3e-05 23.3 0.0 4.7e-05 22.8 0.0 1.1 1 0 0 1 1 1 1 PhoP regulatory network protein YrbL Kdo PF06293.9 KLO08648.1 - 0.0017 17.4 0.1 0.0026 16.8 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 KLO08648.1 - 0.0031 16.5 0.0 0.0047 15.9 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pkinase_Tyr PF07714.12 KLO08649.1 - 8.8e-46 156.0 0.0 1.3e-45 155.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 KLO08649.1 - 3.6e-42 144.3 0.0 6.4e-42 143.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain APH_6_hur PF04655.9 KLO08649.1 - 0.0034 16.5 0.8 2.8 7.0 0.0 3.3 4 0 0 4 4 4 2 Aminoglycoside/hydroxyurea antibiotic resistance kinase APH PF01636.18 KLO08649.1 - 0.014 15.1 0.5 0.14 11.8 0.0 2.6 2 1 0 2 2 2 0 Phosphotransferase enzyme family TAP35_44 PF07265.6 KLO08650.1 - 0.062 13.0 0.0 0.071 12.8 0.0 1.1 1 0 0 1 1 1 0 Tapetum specific protein TAP35/TAP44 Terpene_synth_C PF03936.11 KLO08651.1 - 0.041 13.1 0.0 0.065 12.4 0.0 1.3 1 0 0 1 1 1 0 Terpene synthase family, metal binding domain Terpene_synth_C PF03936.11 KLO08652.1 - 5.5e-10 38.9 0.0 7.1e-10 38.5 0.0 1.1 1 0 0 1 1 1 1 Terpene synthase family, metal binding domain MFS_1 PF07690.11 KLO08653.1 - 1.1e-51 175.5 12.9 1.6e-51 175.1 8.9 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KLO08653.1 - 7.1e-16 57.8 21.8 2.3e-12 46.2 0.5 3.1 3 0 0 3 3 3 3 Sugar (and other) transporter OATP PF03137.15 KLO08653.1 - 0.00062 17.9 0.9 0.00062 17.9 0.7 3.2 2 1 2 4 4 4 1 Organic Anion Transporter Polypeptide (OATP) family DUF4381 PF14316.1 KLO08653.1 - 0.086 12.9 3.3 19 5.3 0.0 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4381) DNA_pol_A_exo1 PF01612.15 KLO08654.1 - 9.8e-36 122.8 0.7 1.9e-35 121.8 0.5 1.5 1 0 0 1 1 1 1 3'-5' exonuclease PMC2NT PF08066.7 KLO08654.1 - 9.1e-15 54.7 0.9 2.2e-14 53.5 0.1 2.1 3 0 0 3 3 3 1 PMC2NT (NUC016) domain HRDC PF00570.18 KLO08654.1 - 4.1e-13 48.8 0.0 8.3e-13 47.8 0.0 1.6 1 0 0 1 1 1 1 HRDC domain DUF3212 PF11486.3 KLO08656.1 - 0.042 13.5 0.9 0.15 11.8 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3212) Ofd1_CTDD PF10637.4 KLO08656.1 - 0.086 11.9 1.1 0.23 10.5 0.3 1.9 2 0 0 2 2 2 0 Oxoglutarate and iron-dependent oxygenase degradation C-term NTR2 PF15458.1 KLO08657.1 - 1.7e-60 204.4 20.0 1.7e-60 204.4 13.9 2.9 3 0 0 3 3 3 1 Nineteen complex-related protein 2 GCFC PF07842.7 KLO08657.1 - 7.8e-06 25.4 0.0 6.1e-05 22.5 0.0 2.1 1 1 1 2 2 2 1 GC-rich sequence DNA-binding factor-like protein DUF1726 PF08351.6 KLO08657.1 - 0.11 12.1 0.0 0.22 11.2 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1726) Tautomerase PF01361.16 KLO08658.1 - 0.14 11.7 0.0 0.35 10.5 0.0 1.6 2 0 0 2 2 2 0 Tautomerase enzyme NTR2 PF15458.1 KLO08660.1 - 3.4e-61 206.6 25.7 4.4e-61 206.3 14.0 2.0 2 0 0 2 2 2 2 Nineteen complex-related protein 2 DUF3292 PF11696.3 KLO08660.1 - 0.006 14.5 0.0 0.006 14.5 0.0 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF3292) EMP24_GP25L PF01105.19 KLO08660.1 - 5.5 6.6 6.3 12 5.6 4.3 1.8 1 1 0 1 1 1 0 emp24/gp25L/p24 family/GOLD Rad60-SLD PF11976.3 KLO08661.1 - 2.8e-13 49.3 0.0 8e-10 38.2 0.0 2.4 2 0 0 2 2 2 2 Ubiquitin-2 like Rad60 SUMO-like PBP1_TM PF14812.1 KLO08661.1 - 0.068 13.4 0.8 0.17 12.2 0.6 1.7 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal HVSL PF09749.4 KLO08662.1 - 3.5e-44 150.6 0.0 4.3e-44 150.3 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised conserved protein WD40 PF00400.27 KLO08663.1 - 0.0045 16.8 0.3 8.4 6.4 0.0 3.9 3 1 0 3 3 3 2 WD domain, G-beta repeat Terpene_synth_C PF03936.11 KLO08665.1 - 4.1e-17 62.3 0.1 1.2e-16 60.7 0.0 1.7 2 0 0 2 2 2 1 Terpene synthase family, metal binding domain Terpene_synth_C PF03936.11 KLO08666.1 - 8.4e-12 44.8 0.3 1.2e-11 44.3 0.2 1.2 1 0 0 1 1 1 1 Terpene synthase family, metal binding domain FAM92 PF06730.6 KLO08666.1 - 0.092 12.0 0.1 0.13 11.6 0.1 1.3 1 0 0 1 1 1 0 FAM92 protein Terpene_synth_C PF03936.11 KLO08667.1 - 2.8e-12 46.4 0.1 3.6e-12 46.0 0.1 1.2 1 0 0 1 1 1 1 Terpene synthase family, metal binding domain Terpene_synth_C PF03936.11 KLO08668.1 - 1.5e-10 40.8 0.4 1.9e-10 40.4 0.3 1.1 1 0 0 1 1 1 1 Terpene synthase family, metal binding domain YqgF PF14639.1 KLO08668.1 - 0.044 13.3 0.0 0.085 12.4 0.0 1.4 1 0 0 1 1 1 0 Holliday-junction resolvase-like of SPT6 DBINO PF13892.1 KLO08668.1 - 0.092 12.7 0.8 0.16 11.9 0.6 1.3 1 0 0 1 1 1 0 DNA-binding domain DEAD PF00270.24 KLO08669.1 - 4e-06 26.4 0.0 5.1e-06 26.0 0.0 1.1 1 0 0 1 1 1 1 DEAD/DEAH box helicase SecA_DEAD PF07517.9 KLO08669.1 - 0.00073 18.9 0.0 0.00082 18.7 0.0 1.0 1 0 0 1 1 1 1 SecA DEAD-like domain ResIII PF04851.10 KLO08669.1 - 0.0021 17.9 0.0 0.0023 17.8 0.0 1.1 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Terpene_synth_C PF03936.11 KLO08670.1 - 6.1e-12 45.3 0.3 8.4e-12 44.8 0.2 1.2 1 0 0 1 1 1 1 Terpene synthase family, metal binding domain Ribosomal_L35p PF01632.14 KLO08672.1 - 9.1e-17 60.7 4.1 1.1e-16 60.4 2.9 1.1 1 0 0 1 1 1 1 Ribosomal protein L35 Ufd2P_core PF10408.4 KLO08673.1 - 3.7e-187 623.4 0.1 4.3e-187 623.1 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin elongating factor core U-box PF04564.10 KLO08673.1 - 1e-28 99.1 3.3 2.1e-28 98.0 0.2 3.3 4 0 0 4 4 4 1 U-box domain Occludin_ELL PF07303.8 KLO08673.1 - 0.094 13.4 0.6 0.37 11.5 0.4 2.0 1 0 0 1 1 1 0 Occludin homology domain DUF2516 PF10724.4 KLO08674.1 - 1.8 8.6 6.8 0.93 9.5 1.6 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF2516) Rhodanese PF00581.15 KLO08675.1 - 3.8e-10 40.1 0.0 4.8e-10 39.7 0.0 1.1 1 0 0 1 1 1 1 Rhodanese-like domain DUF3767 PF12597.3 KLO08676.1 - 8.9e-27 93.1 0.3 1.5e-26 92.3 0.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3767) SSrecog PF03531.9 KLO08677.1 - 4.1e-78 261.7 0.6 8.9e-78 260.6 0.4 1.5 1 1 0 1 1 1 1 Structure-specific recognition protein (SSRP1) Rtt106 PF08512.7 KLO08677.1 - 4.2e-27 93.9 0.0 4.1e-24 84.3 0.0 2.5 2 0 0 2 2 2 2 Histone chaperone Rttp106-like Sigma70_r3 PF04539.11 KLO08677.1 - 0.038 13.8 0.5 0.038 13.8 0.4 2.5 3 0 0 3 3 3 0 Sigma-70 region 3 peroxidase PF00141.18 KLO08679.1 - 1.4e-27 96.6 0.0 6.6e-27 94.4 0.0 1.9 2 0 0 2 2 2 1 Peroxidase DUF3415 PF11895.3 KLO08679.1 - 9.2e-24 83.1 1.9 2e-23 82.0 1.3 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3415) Smr PF01713.16 KLO08681.1 - 3.4e-18 65.5 0.0 7.3e-18 64.5 0.0 1.6 1 0 0 1 1 1 1 Smr domain DUF2781 PF10914.3 KLO08682.1 - 1.1e-38 132.3 2.3 1.3e-38 132.0 1.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2781) Pkinase PF00069.20 KLO08683.1 - 4.6e-45 153.7 0.0 7.7e-45 153.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KLO08683.1 - 9.6e-43 146.1 0.0 1.5e-42 145.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_Tyr PF07714.12 KLO08684.1 - 9.7e-41 139.5 0.0 1.2e-40 139.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 KLO08684.1 - 1.2e-40 139.3 0.0 1.4e-40 139.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.1 KLO08684.1 - 1.9e-06 27.0 0.0 2.9e-06 26.4 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 KLO08684.1 - 0.011 15.5 0.0 0.017 14.8 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pkinase PF00069.20 KLO08685.1 - 2.5e-44 151.3 0.0 3.5e-44 150.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KLO08685.1 - 1.3e-43 148.9 0.0 1.7e-43 148.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KLO08685.1 - 5.2e-05 22.3 0.0 8.6e-05 21.6 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 KLO08685.1 - 0.021 14.5 0.1 0.033 13.9 0.1 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family Enolase_N PF03952.11 KLO08685.1 - 0.032 14.1 0.0 0.053 13.4 0.0 1.3 1 0 0 1 1 1 0 Enolase, N-terminal domain RIO1 PF01163.17 KLO08685.1 - 0.042 13.1 0.1 0.2 10.9 0.0 1.9 2 0 0 2 2 2 0 RIO1 family Cupin_5 PF06172.6 KLO08686.1 - 2.6e-21 75.9 0.0 4.5e-19 68.7 0.0 2.1 1 1 0 1 1 1 1 Cupin superfamily (DUF985) Pkinase PF00069.20 KLO08687.1 - 6.6e-41 140.1 0.0 1e-40 139.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KLO08687.1 - 1.3e-38 132.5 0.0 2e-38 131.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KLO08687.1 - 0.0015 17.5 0.0 0.0033 16.4 0.0 1.4 1 1 0 1 1 1 1 Kinase-like APH PF01636.18 KLO08687.1 - 0.12 12.0 0.2 0.24 11.0 0.1 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.6 KLO08687.1 - 0.15 10.8 0.0 0.23 10.2 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase RIO1 PF01163.17 KLO08687.1 - 0.18 11.1 0.1 2.6 7.3 0.1 2.3 3 0 0 3 3 3 0 RIO1 family Smr PF01713.16 KLO08688.1 - 2e-12 47.0 0.1 3.7e-12 46.2 0.1 1.5 1 0 0 1 1 1 1 Smr domain Smr PF01713.16 KLO08689.1 - 3.3e-11 43.1 0.0 7.2e-11 42.1 0.0 1.6 1 0 0 1 1 1 1 Smr domain Smr PF01713.16 KLO08690.1 - 6.8e-12 45.4 0.0 1.4e-11 44.4 0.0 1.6 1 0 0 1 1 1 1 Smr domain DUF1771 PF08590.5 KLO08690.1 - 7.3e-06 25.9 9.3 1.2e-05 25.1 6.4 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1771) Smr PF01713.16 KLO08691.1 - 1.8e-14 53.6 0.0 3e-14 52.9 0.0 1.4 1 0 0 1 1 1 1 Smr domain Smr PF01713.16 KLO08692.1 - 2.5e-09 37.1 0.0 4.9e-09 36.2 0.0 1.5 1 0 0 1 1 1 1 Smr domain HALZ PF02183.13 KLO08692.1 - 0.0048 16.5 2.3 0.0094 15.6 1.6 1.5 1 0 0 1 1 1 1 Homeobox associated leucine zipper bZIP_1 PF00170.16 KLO08692.1 - 0.014 15.3 0.8 0.028 14.3 0.5 1.5 1 0 0 1 1 1 0 bZIP transcription factor DUF465 PF04325.8 KLO08692.1 - 0.017 14.7 0.1 0.042 13.5 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF465) DivIC PF04977.10 KLO08692.1 - 0.024 14.1 0.6 0.047 13.1 0.4 1.4 1 0 0 1 1 1 0 Septum formation initiator BLOC1_2 PF10046.4 KLO08692.1 - 0.042 13.9 0.1 0.082 13.0 0.1 1.4 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Myosin_tail_1 PF01576.14 KLO08692.1 - 0.064 10.9 0.4 0.095 10.4 0.3 1.1 1 0 0 1 1 1 0 Myosin tail DUF4201 PF13870.1 KLO08692.1 - 0.078 12.4 0.1 0.12 11.8 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4201) Seadorna_VP6 PF07407.6 KLO08692.1 - 0.13 10.9 0.1 0.22 10.2 0.1 1.3 1 0 0 1 1 1 0 Seadornavirus VP6 protein SPT6_acidic PF14632.1 KLO08693.1 - 1.8 8.7 4.4 0.46 10.6 0.6 1.8 2 0 0 2 2 2 0 Acidic N-terminal SPT6 DRMBL PF07522.9 KLO08694.1 - 4.3e-27 94.3 0.0 8.5e-27 93.3 0.0 1.5 1 0 0 1 1 1 1 DNA repair metallo-beta-lactamase Lactamase_B_2 PF12706.2 KLO08694.1 - 1.2e-09 37.9 0.0 2.3e-09 37.0 0.0 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 KLO08694.1 - 0.015 14.9 0.2 0.042 13.4 0.1 1.7 1 1 0 1 1 1 0 Metallo-beta-lactamase superfamily DUF964 PF06133.6 KLO08695.1 - 0.027 14.5 0.6 0.27 11.2 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF964) DUF1993 PF09351.5 KLO08695.1 - 0.055 13.3 0.3 0.12 12.2 0.2 1.5 1 1 1 2 2 2 0 Domain of unknown function (DUF1993) Synaptobrevin PF00957.16 KLO08695.1 - 0.2 11.2 1.5 4.7 6.8 0.0 2.8 2 1 0 3 3 3 0 Synaptobrevin Translin PF01997.11 KLO08696.1 - 0.023 14.2 0.9 4 6.9 0.0 2.9 2 1 0 3 3 3 0 Translin family Polysacc_synt_2 PF02719.10 KLO08696.1 - 0.065 12.1 0.2 0.094 11.5 0.1 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein ISG65-75 PF11727.3 KLO08696.1 - 0.11 11.4 1.6 0.18 10.7 1.0 1.5 1 1 0 1 1 1 0 Invariant surface glycoprotein MCPsignal PF00015.16 KLO08696.1 - 0.8 9.2 3.4 20 4.6 0.5 2.7 1 1 1 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain SUZ PF12752.2 KLO08698.1 - 9.9e-12 45.2 1.1 9.9e-12 45.2 0.7 5.0 6 0 0 6 6 6 1 SUZ domain R3H PF01424.17 KLO08698.1 - 0.0023 17.6 0.0 0.0052 16.4 0.0 1.6 1 0 0 1 1 1 1 R3H domain Aa_trans PF01490.13 KLO08699.1 - 4.5e-86 288.8 23.7 5.1e-86 288.7 16.4 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.8 KLO08699.1 - 2.4e-05 23.3 15.5 2.4e-05 23.3 10.7 2.4 2 1 0 2 2 2 1 Tryptophan/tyrosine permease family Ribosomal_S4e PF00900.15 KLO08704.1 - 3.3e-20 71.5 0.0 6.7e-20 70.5 0.0 1.5 1 0 0 1 1 1 1 Ribosomal family S4e KOW PF00467.24 KLO08704.1 - 2.5e-07 30.1 1.3 7.6e-07 28.6 0.9 1.9 1 0 0 1 1 1 1 KOW motif NMD3 PF04981.8 KLO08704.1 - 0.049 12.7 0.0 0.067 12.3 0.0 1.2 1 0 0 1 1 1 0 NMD3 family F-box-like PF12937.2 KLO08706.1 - 2e-08 33.8 0.6 8.3e-08 31.8 0.3 2.2 2 0 0 2 2 2 1 F-box-like F-box-like PF12937.2 KLO08707.1 - 1.9e-11 43.4 3.9 3.5e-10 39.4 1.8 3.1 3 0 0 3 3 3 1 F-box-like LRR_4 PF12799.2 KLO08707.1 - 0.0096 15.5 5.6 1.7 8.3 0.2 5.1 3 2 3 6 6 6 2 Leucine Rich repeats (2 copies) F-box PF00646.28 KLO08707.1 - 0.054 13.1 6.8 0.029 14.0 1.8 2.8 2 1 0 2 2 2 0 F-box domain F-box-like PF12937.2 KLO08708.1 - 6e-12 45.0 6.3 4.2e-11 42.3 2.8 2.8 2 1 0 2 2 2 1 F-box-like F-box PF00646.28 KLO08708.1 - 0.00034 20.1 2.8 1.5 8.6 0.2 3.4 3 0 0 3 3 3 3 F-box domain F-box-like PF12937.2 KLO08710.1 - 3.4e-07 29.8 0.3 3.4e-07 29.8 0.2 3.3 4 0 0 4 4 4 1 F-box-like F-box-like PF12937.2 KLO08711.1 - 4.2e-11 42.3 2.7 7.5e-11 41.5 0.4 2.6 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 KLO08711.1 - 0.0026 17.3 3.2 0.035 13.7 2.2 2.5 1 1 0 1 1 1 1 F-box domain F-box-like PF12937.2 KLO08714.1 - 7.1e-06 25.6 0.3 2e-05 24.2 0.2 1.9 1 0 0 1 1 1 1 F-box-like DUF4626 PF15422.1 KLO08715.1 - 0.14 12.1 0.6 0.21 11.5 0.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4626) DctQ PF04290.7 KLO08716.1 - 0.031 14.0 0.7 0.041 13.6 0.0 1.5 2 0 0 2 2 2 0 Tripartite ATP-independent periplasmic transporters, DctQ component F-box-like PF12937.2 KLO08719.1 - 4.7e-09 35.8 0.8 6.5e-08 32.1 0.6 2.5 2 0 0 2 2 2 1 F-box-like F-box-like PF12937.2 KLO08720.1 - 1.4e-12 47.1 3.3 4.4e-12 45.5 0.5 3.0 3 0 0 3 3 3 1 F-box-like F-box PF00646.28 KLO08720.1 - 9.9e-05 21.8 3.3 0.004 16.7 0.9 2.8 2 0 0 2 2 2 2 F-box domain MCM2_N PF12619.3 KLO08721.1 - 0.09 12.7 0.5 0.12 12.4 0.3 1.1 1 0 0 1 1 1 0 Mini-chromosome maintenance protein 2 Endonuc-FokI_C PF09254.6 KLO08721.1 - 0.15 11.1 0.0 0.19 10.8 0.0 1.1 1 0 0 1 1 1 0 Restriction endonuclease FokI, C terminal F-box-like PF12937.2 KLO08722.1 - 2.7e-10 39.8 0.6 1.1e-09 37.8 0.4 2.2 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KLO08722.1 - 0.0083 15.7 7.3 0.043 13.4 3.4 3.1 2 1 0 2 2 2 1 F-box domain F-box-like PF12937.2 KLO08723.1 - 3.3e-11 42.7 3.5 7e-11 41.6 0.3 2.9 3 0 0 3 3 3 1 F-box-like F-box-like PF12937.2 KLO08725.1 - 3.1e-10 39.6 3.8 1.4e-09 37.4 2.6 2.2 1 1 0 1 1 1 1 F-box-like F-box PF00646.28 KLO08725.1 - 0.15 11.7 5.6 0.1 12.2 1.3 2.5 2 0 0 2 2 2 0 F-box domain F-box-like PF12937.2 KLO08726.1 - 1.9e-10 40.2 1.9 7.4e-10 38.3 1.3 2.1 1 1 0 1 1 1 1 F-box-like F-box PF00646.28 KLO08726.1 - 0.13 11.9 3.9 2.5 7.8 2.7 2.6 1 1 0 1 1 1 0 F-box domain F-box-like PF12937.2 KLO08728.1 - 9.7e-11 41.2 0.2 1.9e-08 33.8 0.7 3.2 2 1 0 2 2 2 1 F-box-like LRR_4 PF12799.2 KLO08728.1 - 0.22 11.1 3.5 20 4.9 0.1 3.6 2 2 1 3 3 3 0 Leucine Rich repeats (2 copies) F-box PF00646.28 KLO08728.1 - 0.25 11.0 11.2 11 5.8 5.5 3.2 2 1 0 2 2 2 0 F-box domain F-box-like PF12937.2 KLO08729.1 - 3.8e-12 45.7 3.3 1.1e-11 44.2 1.5 2.4 2 1 0 2 2 2 1 F-box-like F-box PF00646.28 KLO08729.1 - 0.00039 19.9 1.1 0.8 9.4 0.0 3.2 3 0 0 3 3 3 2 F-box domain AAA_2 PF07724.9 KLO08732.1 - 2e-36 125.4 0.0 4.1e-36 124.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) Ank PF00023.25 KLO08732.1 - 4.6e-17 60.8 0.8 1.6e-08 33.8 0.0 4.8 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.1 KLO08732.1 - 7.7e-15 54.5 0.2 5.6e-07 29.6 0.0 5.0 5 0 0 5 5 5 2 Ankyrin repeats (many copies) Ank_2 PF12796.2 KLO08732.1 - 2.3e-14 53.4 0.0 3.9e-07 30.3 0.0 4.3 2 1 1 3 3 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.1 KLO08732.1 - 1.8e-10 39.9 0.3 0.0015 18.5 0.0 4.6 4 0 0 4 4 4 2 Ankyrin repeat AAA_5 PF07728.9 KLO08732.1 - 3.3e-09 36.6 0.0 1.3e-08 34.6 0.0 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) Ank_4 PF13637.1 KLO08732.1 - 4.4e-09 36.6 0.4 0.013 16.0 0.0 5.0 4 2 1 5 5 5 2 Ankyrin repeats (many copies) ClpB_D2-small PF10431.4 KLO08732.1 - 5.1e-06 26.2 0.1 1.1e-05 25.1 0.0 1.6 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA PF00004.24 KLO08732.1 - 9.5e-06 25.8 0.0 2.5e-05 24.4 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 KLO08732.1 - 0.00025 20.5 0.0 0.00058 19.3 0.0 1.6 1 0 0 1 1 1 1 Sigma-54 interaction domain Torsin PF06309.6 KLO08732.1 - 0.0019 18.0 0.0 0.0039 17.0 0.0 1.4 1 0 0 1 1 1 1 Torsin AAA_22 PF13401.1 KLO08732.1 - 0.003 17.6 0.0 0.0081 16.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 KLO08732.1 - 0.081 12.8 0.0 0.23 11.4 0.0 1.7 1 1 1 2 2 2 0 AAA ATPase domain RNA_helicase PF00910.17 KLO08732.1 - 0.13 12.4 0.0 0.31 11.2 0.0 1.6 1 0 0 1 1 1 0 RNA helicase Mg_chelatase PF01078.16 KLO08732.1 - 0.15 11.1 0.0 0.34 10.0 0.0 1.6 1 1 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_17 PF13207.1 KLO08732.1 - 1.1 10.0 0.0 1.1 10.0 0.0 2.7 3 0 0 3 3 2 0 AAA domain Integrase_Zn PF02022.14 KLO08733.1 - 0.34 10.3 2.1 0.82 9.1 0.1 2.3 2 0 0 2 2 2 0 Integrase Zinc binding domain AAA_2 PF07724.9 KLO08734.1 - 5.2e-24 85.0 0.9 4e-23 82.1 0.6 2.2 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) Ank_2 PF12796.2 KLO08734.1 - 3.8e-17 62.4 0.0 1.5e-07 31.6 0.1 3.6 2 2 1 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 KLO08734.1 - 6.9e-17 60.3 0.4 5.7e-06 25.8 0.0 4.9 4 0 0 4 4 4 3 Ankyrin repeat Ank_5 PF13857.1 KLO08734.1 - 1.5e-13 50.4 0.0 0.0023 18.1 0.0 4.9 5 0 0 5 5 4 4 Ankyrin repeats (many copies) Ank_4 PF13637.1 KLO08734.1 - 8.6e-13 48.4 0.5 0.04 14.4 0.0 5.0 3 1 1 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 KLO08734.1 - 1.3e-08 34.2 0.6 0.11 12.8 0.0 4.9 4 0 0 4 4 4 2 Ankyrin repeat ClpB_D2-small PF10431.4 KLO08734.1 - 3.9e-07 29.8 0.1 8.2e-07 28.8 0.1 1.5 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA_5 PF07728.9 KLO08734.1 - 3.2e-06 26.9 0.1 1.8e-05 24.5 0.1 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA PF00004.24 KLO08734.1 - 1.3e-05 25.3 0.0 4.5e-05 23.6 0.0 2.0 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 KLO08734.1 - 0.0001 21.8 0.0 0.00026 20.5 0.0 1.7 1 0 0 1 1 1 1 Sigma-54 interaction domain Imm29 PF15575.1 KLO08734.1 - 0.002 17.7 0.1 0.0072 15.9 0.0 2.0 2 0 0 2 2 2 1 Immunity protein 29 Torsin PF06309.6 KLO08734.1 - 0.013 15.3 0.0 0.03 14.2 0.0 1.5 1 0 0 1 1 1 0 Torsin AAA_22 PF13401.1 KLO08734.1 - 0.02 15.0 0.0 0.084 13.0 0.0 2.0 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.1 KLO08734.1 - 0.03 14.3 0.1 0.3 11.0 0.0 2.6 3 0 0 3 3 2 0 AAA ATPase domain DUF3572 PF12096.3 KLO08734.1 - 0.076 12.8 0.0 1.7 8.5 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3572) HTH_21 PF13276.1 KLO08734.1 - 0.11 12.5 0.1 0.27 11.2 0.1 1.6 1 0 0 1 1 1 0 HTH-like domain RNA_helicase PF00910.17 KLO08734.1 - 0.12 12.5 0.0 0.32 11.1 0.0 1.7 1 0 0 1 1 1 0 RNA helicase PEPCK_ATP PF01293.15 KLO08734.1 - 0.13 10.7 0.0 0.23 9.9 0.0 1.3 1 0 0 1 1 1 0 Phosphoenolpyruvate carboxykinase ANAPC15 PF15243.1 KLO08734.1 - 0.38 10.8 6.6 44 4.2 4.4 2.7 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 15 GMC_oxred_N PF00732.14 KLO08735.1 - 1.7e-65 221.1 0.0 2.2e-65 220.7 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 KLO08735.1 - 7.8e-37 126.7 0.0 1.4e-36 125.9 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 KLO08735.1 - 1.2e-05 24.3 0.7 0.00063 18.7 0.2 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KLO08735.1 - 4.6e-05 23.3 0.1 0.0002 21.3 0.1 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 KLO08735.1 - 0.00025 20.0 0.8 0.00089 18.2 0.4 1.8 2 0 0 2 2 2 1 FAD binding domain Lycopene_cycl PF05834.7 KLO08735.1 - 0.00066 18.6 0.2 0.0012 17.8 0.2 1.4 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_2 PF07992.9 KLO08735.1 - 0.013 15.3 0.1 0.045 13.6 0.0 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 KLO08735.1 - 0.018 13.5 0.1 0.035 12.5 0.1 1.4 1 0 0 1 1 1 0 HI0933-like protein Thi4 PF01946.12 KLO08735.1 - 0.018 14.1 0.1 0.035 13.2 0.1 1.4 1 0 0 1 1 1 0 Thi4 family UCR_TM PF02921.9 KLO08735.1 - 0.05 13.8 0.2 0.1 12.8 0.1 1.5 1 0 0 1 1 1 0 Ubiquinol cytochrome reductase transmembrane region BTB PF00651.26 KLO08736.1 - 6.2e-07 29.3 0.1 3.1e-06 27.1 0.1 2.0 1 1 0 1 1 1 1 BTB/POZ domain OAR PF03826.12 KLO08736.1 - 0.053 13.0 0.3 0.14 11.6 0.2 1.8 1 0 0 1 1 1 0 OAR domain FF PF01846.14 KLO08737.1 - 0.14 12.1 0.0 2.9 7.9 0.0 2.4 2 0 0 2 2 2 0 FF domain DUF3176 PF11374.3 KLO08737.1 - 0.15 11.9 4.1 0.14 12.0 0.6 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3176) GMC_oxred_N PF00732.14 KLO08738.1 - 3e-66 223.5 0.0 3.9e-66 223.2 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 KLO08738.1 - 1.9e-36 125.5 0.0 3.2e-36 124.7 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 KLO08738.1 - 1.4e-05 24.2 0.6 9.1e-05 21.5 0.2 2.0 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KLO08738.1 - 0.00011 22.1 0.1 0.0004 20.3 0.1 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 KLO08738.1 - 0.00049 19.0 2.1 0.00095 18.1 0.3 2.1 2 1 0 2 2 2 1 FAD binding domain Lycopene_cycl PF05834.7 KLO08738.1 - 0.0015 17.5 0.1 0.0023 16.8 0.1 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_2 PF07992.9 KLO08738.1 - 0.0057 16.5 0.2 0.015 15.2 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 KLO08738.1 - 0.014 14.5 0.1 0.029 13.4 0.1 1.5 1 0 0 1 1 1 0 Thi4 family HI0933_like PF03486.9 KLO08738.1 - 0.026 12.9 0.2 0.046 12.1 0.1 1.3 1 0 0 1 1 1 0 HI0933-like protein Pyr_redox_3 PF13738.1 KLO08738.1 - 0.042 13.8 0.1 0.94 9.4 0.1 2.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase UCR_TM PF02921.9 KLO08738.1 - 0.15 12.3 0.0 0.32 11.2 0.0 1.5 1 0 0 1 1 1 0 Ubiquinol cytochrome reductase transmembrane region NAD_binding_9 PF13454.1 KLO08738.1 - 0.15 11.8 0.0 0.35 10.6 0.0 1.7 1 0 0 1 1 1 0 FAD-NAD(P)-binding An_peroxidase PF03098.10 KLO08740.1 - 1.6e-76 257.8 0.0 2.8e-74 250.3 0.0 2.3 1 1 0 1 1 1 1 Animal haem peroxidase p450 PF00067.17 KLO08740.1 - 5.1e-07 28.5 0.5 2.7e-06 26.2 0.0 2.2 3 0 0 3 3 3 1 Cytochrome P450 HHH_4 PF14490.1 KLO08740.1 - 0.12 12.1 0.0 0.7 9.6 0.0 2.1 2 0 0 2 2 2 0 Helix-hairpin-helix containing domain AATase PF07247.7 KLO08741.1 - 1.3e-31 109.7 0.0 1.8e-31 109.2 0.0 1.1 1 0 0 1 1 1 1 Alcohol acetyltransferase AAA_2 PF07724.9 KLO08742.1 - 4.6e-35 121.0 0.0 1.1e-34 119.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) Ank_2 PF12796.2 KLO08742.1 - 1.2e-20 73.6 0.7 9.4e-08 32.2 0.1 3.4 3 0 0 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 KLO08742.1 - 4.9e-19 67.0 0.5 1.6e-07 30.7 0.1 4.6 4 0 0 4 4 4 3 Ankyrin repeat Ank_5 PF13857.1 KLO08742.1 - 1.6e-18 66.3 0.8 5.6e-06 26.4 0.1 4.4 3 2 2 5 5 5 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 KLO08742.1 - 6.7e-14 50.6 0.9 0.00019 21.3 0.0 4.5 5 0 0 5 5 3 3 Ankyrin repeat Ank_4 PF13637.1 KLO08742.1 - 1.3e-13 51.0 0.7 0.021 15.3 0.0 4.5 4 0 0 4 4 4 3 Ankyrin repeats (many copies) AAA_5 PF07728.9 KLO08742.1 - 6e-10 38.9 0.0 3.5e-09 36.5 0.0 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA PF00004.24 KLO08742.1 - 2e-07 31.2 0.0 4.8e-07 30.0 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.4 KLO08742.1 - 3.9e-06 26.6 0.1 8.4e-06 25.6 0.1 1.6 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein Sigma54_activat PF00158.21 KLO08742.1 - 6.9e-05 22.3 0.0 0.00015 21.2 0.0 1.5 1 0 0 1 1 1 1 Sigma-54 interaction domain G-alpha PF00503.15 KLO08742.1 - 0.0028 16.4 1.7 0.0054 15.4 1.2 1.4 1 0 0 1 1 1 1 G-protein alpha subunit Mg_chelatase PF01078.16 KLO08742.1 - 0.0044 16.2 0.0 0.0083 15.3 0.0 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_22 PF13401.1 KLO08742.1 - 0.0056 16.8 0.0 0.024 14.7 0.0 2.0 1 1 0 1 1 1 1 AAA domain Torsin PF06309.6 KLO08742.1 - 0.018 14.9 0.0 0.068 13.0 0.0 1.9 2 0 0 2 2 2 0 Torsin ABC_tran PF00005.22 KLO08742.1 - 0.028 14.7 0.0 0.12 12.7 0.0 2.1 1 0 0 1 1 1 0 ABC transporter AAA_16 PF13191.1 KLO08742.1 - 0.033 14.1 0.7 0.2 11.6 0.0 2.6 3 0 0 3 3 3 0 AAA ATPase domain AAA_17 PF13207.1 KLO08742.1 - 0.07 13.9 0.1 0.39 11.5 0.0 2.4 2 0 0 2 2 1 0 AAA domain DUF3853 PF12964.2 KLO08742.1 - 0.11 12.2 0.1 1.1 9.0 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3853) SR-25 PF10500.4 KLO08742.1 - 0.11 11.8 16.1 0.2 11.1 11.2 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Rtf2 PF04641.7 KLO08742.1 - 0.14 11.3 13.8 0.24 10.5 9.5 1.3 1 0 0 1 1 1 0 Rtf2 RING-finger CDC45 PF02724.9 KLO08742.1 - 0.14 10.1 11.3 0.25 9.3 7.8 1.3 1 0 0 1 1 1 0 CDC45-like protein SRP-alpha_N PF04086.8 KLO08742.1 - 0.15 11.4 11.4 0.25 10.6 7.9 1.3 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal DUF755 PF05501.6 KLO08742.1 - 0.89 9.6 11.5 1.7 8.7 8.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF755) Cwf_Cwc_15 PF04889.7 KLO08742.1 - 1.5 8.4 18.4 3.5 7.2 12.8 1.5 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein DUF1510 PF07423.6 KLO08742.1 - 2.3 7.5 18.4 4.6 6.5 12.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Torsin PF06309.6 KLO08743.1 - 0.00052 19.9 0.0 0.00081 19.2 0.0 1.3 1 0 0 1 1 1 1 Torsin IstB_IS21 PF01695.12 KLO08743.1 - 0.021 14.2 0.0 0.034 13.5 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_25 PF13481.1 KLO08743.1 - 0.021 14.2 0.0 0.04 13.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.1 KLO08743.1 - 0.03 14.2 0.0 0.069 13.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.1 KLO08743.1 - 0.043 13.8 0.0 0.081 12.9 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain AAA_2 PF07724.9 KLO08744.1 - 4.5e-31 108.0 0.0 8.4e-31 107.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) Ank_2 PF12796.2 KLO08744.1 - 7.3e-21 74.3 0.0 2.5e-06 27.7 0.0 4.1 1 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 KLO08744.1 - 7.9e-19 66.4 0.6 5.8e-09 35.3 0.1 4.7 4 0 0 4 4 4 4 Ankyrin repeat Ank_4 PF13637.1 KLO08744.1 - 3.9e-18 65.4 0.1 0.00016 22.0 0.0 4.6 4 0 0 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 KLO08744.1 - 1.9e-16 58.4 0.6 7e-06 25.7 0.1 5.1 5 0 0 5 5 4 3 Ankyrin repeat Ank_5 PF13857.1 KLO08744.1 - 1.5e-13 50.5 0.1 1.7e-07 31.2 0.0 5.1 4 1 1 5 5 5 1 Ankyrin repeats (many copies) AAA_5 PF07728.9 KLO08744.1 - 5.6e-11 42.3 0.0 1.2e-10 41.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) ClpB_D2-small PF10431.4 KLO08744.1 - 9.6e-08 31.8 0.1 1.8e-07 30.9 0.1 1.5 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA PF00004.24 KLO08744.1 - 3.6e-07 30.4 0.0 9.8e-07 29.0 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 KLO08744.1 - 1.3e-06 28.0 0.0 2.6e-06 26.9 0.0 1.6 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA_22 PF13401.1 KLO08744.1 - 0.0017 18.5 0.0 0.0092 16.1 0.0 2.2 1 1 0 1 1 1 1 AAA domain AAA_3 PF07726.6 KLO08744.1 - 0.0019 17.8 0.0 0.021 14.4 0.0 2.3 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Mg_chelatase PF01078.16 KLO08744.1 - 0.0071 15.5 0.0 0.013 14.7 0.0 1.3 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_17 PF13207.1 KLO08744.1 - 0.038 14.7 0.0 0.12 13.2 0.0 1.9 2 0 0 2 2 1 0 AAA domain AAA_21 PF13304.1 KLO08744.1 - 0.039 13.9 0.8 0.11 12.4 0.0 2.1 3 0 0 3 3 3 0 AAA domain Torsin PF06309.6 KLO08744.1 - 0.04 13.7 0.0 0.081 12.8 0.0 1.4 1 0 0 1 1 1 0 Torsin AAA_16 PF13191.1 KLO08744.1 - 0.12 12.3 0.1 0.73 9.7 0.0 2.3 1 1 0 2 2 2 0 AAA ATPase domain AAA_25 PF13481.1 KLO08744.1 - 0.15 11.4 0.0 0.74 9.1 0.0 2.1 2 0 0 2 2 2 0 AAA domain Coatomer_E PF04733.9 KLO08745.1 - 1.2e-39 136.2 0.0 1.4e-39 136.0 0.0 1.0 1 0 0 1 1 1 1 Coatomer epsilon subunit TPR_8 PF13181.1 KLO08745.1 - 0.001 18.6 0.1 0.056 13.2 0.1 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.12 KLO08745.1 - 0.0055 16.5 3.5 1 9.4 0.1 3.3 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.1 KLO08745.1 - 0.016 15.4 2.5 0.07 13.4 0.2 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.1 KLO08745.1 - 0.032 14.1 0.5 3.3 7.7 0.0 2.6 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_11 PF13414.1 KLO08745.1 - 0.055 13.1 0.5 3.6 7.3 0.0 2.7 2 1 1 3 3 3 0 TPR repeat TPR_9 PF13371.1 KLO08745.1 - 0.079 12.8 2.9 2.2 8.1 0.0 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.23 KLO08745.1 - 0.099 12.2 0.1 14 5.4 0.1 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.1 KLO08745.1 - 0.14 12.9 7.7 0.4 11.4 0.2 4.0 5 0 0 5 5 5 0 Tetratricopeptide repeat Tmemb_18A PF09771.4 KLO08746.1 - 0.0017 18.3 0.0 0.0024 17.8 0.0 1.2 1 0 0 1 1 1 1 Transmembrane protein 188 AATase PF07247.7 KLO08747.1 - 1e-40 139.7 0.0 1.2e-40 139.4 0.0 1.0 1 0 0 1 1 1 1 Alcohol acetyltransferase Condensation PF00668.15 KLO08747.1 - 0.00045 19.1 0.1 0.00099 18.0 0.0 1.5 2 0 0 2 2 2 1 Condensation domain Period_C PF12114.3 KLO08747.1 - 0.11 12.0 0.0 0.18 11.3 0.0 1.2 1 0 0 1 1 1 0 Period protein 2/3C-terminal region AAA_2 PF07724.9 KLO08748.1 - 2.9e-35 121.7 0.3 5.6e-35 120.7 0.0 1.7 2 0 0 2 2 1 1 AAA domain (Cdc48 subfamily) Ank_2 PF12796.2 KLO08748.1 - 8.1e-23 80.5 0.0 4.1e-08 33.4 0.1 4.1 1 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.1 KLO08748.1 - 7.9e-22 76.7 0.3 2.6e-07 30.6 0.0 6.4 5 2 2 7 7 6 4 Ankyrin repeats (many copies) Ank PF00023.25 KLO08748.1 - 1.5e-21 75.0 3.0 5.7e-08 32.1 0.2 5.9 6 0 0 6 6 5 4 Ankyrin repeat Ank_3 PF13606.1 KLO08748.1 - 7.5e-18 62.8 2.7 5.8e-05 22.9 0.1 5.9 5 0 0 5 5 5 3 Ankyrin repeat Ank_4 PF13637.1 KLO08748.1 - 1.2e-16 60.7 0.2 0.0088 16.5 0.0 5.0 5 0 0 5 5 5 3 Ankyrin repeats (many copies) AAA_5 PF07728.9 KLO08748.1 - 5.2e-10 39.1 0.1 3e-09 36.7 0.0 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA PF00004.24 KLO08748.1 - 1.5e-07 31.6 0.0 4.1e-07 30.2 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.4 KLO08748.1 - 3.1e-07 30.1 0.1 8.8e-07 28.7 0.1 1.8 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein Sigma54_activat PF00158.21 KLO08748.1 - 0.0001 21.8 0.0 0.00022 20.7 0.0 1.5 1 0 0 1 1 1 1 Sigma-54 interaction domain Mg_chelatase PF01078.16 KLO08748.1 - 0.0057 15.8 0.0 0.016 14.3 0.0 1.7 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI G-alpha PF00503.15 KLO08748.1 - 0.0061 15.2 0.3 0.011 14.4 0.2 1.3 1 0 0 1 1 1 1 G-protein alpha subunit AAA_22 PF13401.1 KLO08748.1 - 0.014 15.5 0.0 0.11 12.6 0.0 2.5 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.1 KLO08748.1 - 0.034 14.1 0.0 0.49 10.3 0.0 2.6 2 0 0 2 2 2 0 AAA ATPase domain Imm29 PF15575.1 KLO08748.1 - 0.042 13.4 0.0 12 5.3 0.0 3.1 3 0 0 3 3 3 0 Immunity protein 29 Torsin PF06309.6 KLO08748.1 - 0.049 13.5 0.0 0.11 12.3 0.0 1.6 1 0 0 1 1 1 0 Torsin ABC_tran PF00005.22 KLO08748.1 - 0.051 13.8 0.0 0.15 12.3 0.0 1.8 1 0 0 1 1 1 0 ABC transporter DUF3647 PF12363.3 KLO08748.1 - 0.068 13.2 0.0 14 5.8 0.0 3.5 4 0 0 4 4 3 0 Phage protein AAA_2 PF07724.9 KLO08749.1 - 3.6e-38 131.1 0.0 6.4e-38 130.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) Ank_2 PF12796.2 KLO08749.1 - 5e-23 81.2 0.0 1.1e-06 28.8 0.3 3.6 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 KLO08749.1 - 2e-19 68.3 4.3 8.6e-07 28.4 0.0 5.9 6 0 0 6 6 6 3 Ankyrin repeat Ank_4 PF13637.1 KLO08749.1 - 1.4e-17 63.7 1.1 4.1e-05 23.9 0.1 4.8 4 0 0 4 4 4 3 Ankyrin repeats (many copies) Ank_5 PF13857.1 KLO08749.1 - 7.1e-17 61.0 1.2 0.00018 21.6 0.0 5.8 4 1 1 5 5 5 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 KLO08749.1 - 2e-14 52.2 2.8 2.8e-05 23.9 0.0 5.5 5 0 0 5 5 5 3 Ankyrin repeat AAA_5 PF07728.9 KLO08749.1 - 3.9e-10 39.6 0.0 1.8e-09 37.4 0.0 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA PF00004.24 KLO08749.1 - 1.3e-07 31.9 0.0 2.9e-07 30.7 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.4 KLO08749.1 - 1.1e-05 25.2 0.0 2.4e-05 24.1 0.0 1.6 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein Sigma54_activat PF00158.21 KLO08749.1 - 6.2e-05 22.5 0.0 0.00014 21.3 0.0 1.5 1 0 0 1 1 1 1 Sigma-54 interaction domain Torsin PF06309.6 KLO08749.1 - 0.0012 18.7 0.0 0.0028 17.5 0.0 1.5 1 0 0 1 1 1 1 Torsin AAA_25 PF13481.1 KLO08749.1 - 0.0046 16.3 0.1 0.045 13.1 0.0 2.2 2 0 0 2 2 2 1 AAA domain Mg_chelatase PF01078.16 KLO08749.1 - 0.0057 15.8 0.0 0.011 14.8 0.0 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_22 PF13401.1 KLO08749.1 - 0.0081 16.2 0.5 0.093 12.8 0.1 2.8 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.1 KLO08749.1 - 0.014 15.3 0.2 0.084 12.8 0.0 2.4 3 0 0 3 3 3 0 AAA ATPase domain AAA_3 PF07726.6 KLO08749.1 - 0.046 13.3 0.0 1.3 8.6 0.0 2.6 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) HU-DNA_bdg PF14848.1 KLO08749.1 - 0.055 13.2 0.0 0.12 12.1 0.0 1.5 1 0 0 1 1 1 0 DNA-binding domain DUF4196 PF13846.1 KLO08749.1 - 0.093 13.0 0.2 0.19 11.9 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4196) AAA_17 PF13207.1 KLO08749.1 - 0.22 12.3 2.3 0.58 10.9 0.3 2.7 2 1 0 2 2 2 0 AAA domain 3-HAO PF06052.7 KLO08750.1 - 0.034 13.5 0.0 0.077 12.4 0.0 1.5 1 0 0 1 1 1 0 3-hydroxyanthranilic acid dioxygenase DUF3484 PF11983.3 KLO08752.1 - 0.63 10.9 5.1 1.1 10.1 3.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3484) 2OG-FeII_Oxy_2 PF13532.1 KLO08753.1 - 0.6 9.9 3.8 0.67 9.7 2.6 1.1 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily PAT1 PF09770.4 KLO08753.1 - 6.9 4.7 25.1 7.9 4.5 17.4 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 zf-MYND PF01753.13 KLO08754.1 - 1.7e-07 30.9 16.3 1.7e-07 30.9 11.3 2.8 2 1 1 3 3 3 1 MYND finger zf-MYND PF01753.13 KLO08755.1 - 2.8e-08 33.4 16.0 2.8e-08 33.4 11.1 2.4 2 0 0 2 2 2 1 MYND finger zf-Mss51 PF13824.1 KLO08755.1 - 0.76 9.6 7.4 0.8 9.6 2.7 2.6 2 0 0 2 2 2 0 Zinc-finger of mitochondrial splicing suppressor 51 zf-MYND PF01753.13 KLO08756.1 - 4.8e-09 35.9 10.7 1.2e-08 34.6 7.4 1.7 1 0 0 1 1 1 1 MYND finger WD40 PF00400.27 KLO08758.1 - 8.7e-36 120.5 13.9 5.8e-12 45.0 0.4 7.3 7 0 0 7 7 7 6 WD domain, G-beta repeat Sof1 PF04158.9 KLO08758.1 - 8.5e-23 80.2 6.9 2.1e-22 78.9 4.8 1.7 1 0 0 1 1 1 1 Sof1-like domain DUF4613 PF15390.1 KLO08758.1 - 0.049 11.8 0.5 0.084 11.0 0.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4613) AMP-binding PF00501.23 KLO08759.1 - 4.1e-96 321.9 1.5 4.7e-96 321.7 0.2 1.6 2 0 0 2 2 2 1 AMP-binding enzyme AMP-binding_C PF13193.1 KLO08759.1 - 5.1e-22 78.6 0.8 5.4e-21 75.3 0.1 2.8 3 0 0 3 3 3 1 AMP-binding enzyme C-terminal domain Crp PF00325.15 KLO08759.1 - 0.058 12.8 0.0 0.12 11.8 0.0 1.6 1 0 0 1 1 1 0 Bacterial regulatory proteins, crp family DUF2461 PF09365.5 KLO08760.1 - 9.3e-56 188.5 0.1 3.1e-55 186.8 0.0 1.9 2 1 0 2 2 2 1 Conserved hypothetical protein (DUF2461) IER PF05760.7 KLO08760.1 - 4.9 6.9 15.7 6.7 6.5 10.9 1.2 1 0 0 1 1 1 0 Immediate early response protein (IER) FAD_oxidored PF12831.2 KLO08762.1 - 0.00026 20.2 0.0 0.00089 18.4 0.0 1.7 1 1 0 1 1 1 1 FAD dependent oxidoreductase Trp_halogenase PF04820.9 KLO08762.1 - 0.00032 19.4 0.1 0.21 10.1 0.0 2.7 3 0 0 3 3 3 2 Tryptophan halogenase FAD_binding_2 PF00890.19 KLO08762.1 - 0.058 12.2 0.1 1.2 7.8 0.0 2.1 2 0 0 2 2 2 0 FAD binding domain FAD_oxidored PF12831.2 KLO08763.1 - 6.4e-06 25.5 0.0 1.6e-05 24.1 0.0 1.5 1 1 0 1 1 1 1 FAD dependent oxidoreductase Trp_halogenase PF04820.9 KLO08763.1 - 0.00093 17.9 0.3 0.1 11.2 0.0 2.8 3 0 0 3 3 3 2 Tryptophan halogenase GDE_N PF12439.3 KLO08763.1 - 0.084 12.1 0.0 0.14 11.3 0.0 1.3 1 0 0 1 1 1 0 Glycogen debranching enzyme N terminal FAD_oxidored PF12831.2 KLO08764.1 - 0.0036 16.4 0.0 0.013 14.6 0.0 1.7 1 1 0 1 1 1 1 FAD dependent oxidoreductase Trp_halogenase PF04820.9 KLO08764.1 - 0.015 13.9 0.1 8 4.9 0.0 3.0 3 0 0 3 3 3 0 Tryptophan halogenase DAO PF01266.19 KLO08764.1 - 0.1 11.4 0.1 0.42 9.4 0.0 1.9 1 1 0 2 2 2 0 FAD dependent oxidoreductase UPF0227 PF05728.7 KLO08764.1 - 0.19 11.4 0.0 0.32 10.6 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) F-box-like PF12937.2 KLO08765.1 - 4.3e-07 29.5 2.2 4.6e-07 29.4 0.2 2.2 2 0 0 2 2 2 1 F-box-like F-box-like_2 PF13013.1 KLO08765.1 - 0.15 11.8 0.7 0.47 10.1 0.5 2.1 1 1 0 1 1 1 0 F-box-like domain FAD_oxidored PF12831.2 KLO08766.1 - 0.02 14.0 0.0 0.13 11.3 0.0 1.9 1 1 0 1 1 1 0 FAD dependent oxidoreductase PSD2 PF07624.6 KLO08766.1 - 0.14 11.8 0.0 0.6 9.7 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1585) NAD_binding_6 PF08030.7 KLO08768.1 - 3.8e-39 134.0 0.0 5.8e-39 133.4 0.0 1.3 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.7 KLO08768.1 - 2.3e-21 75.6 0.0 5.1e-21 74.5 0.0 1.5 1 0 0 1 1 1 1 FAD-binding domain Ferric_reduct PF01794.14 KLO08768.1 - 6e-13 48.9 17.3 6e-13 48.9 12.0 3.0 2 1 0 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_6 PF00970.19 KLO08768.1 - 2.2e-05 24.4 0.0 4.7e-05 23.4 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.16 KLO08768.1 - 0.035 14.6 0.0 0.57 10.7 0.0 2.4 1 1 0 1 1 1 0 Oxidoreductase NAD-binding domain Acetyltransf_7 PF13508.1 KLO08769.1 - 1.9e-07 31.1 0.1 3.3e-07 30.3 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 KLO08769.1 - 1.8e-06 27.8 0.0 2.8e-06 27.2 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_9 PF13527.1 KLO08769.1 - 5.2e-06 26.3 0.1 1.3e-05 25.0 0.0 1.6 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 KLO08769.1 - 0.00066 19.7 0.0 0.0011 19.0 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 KLO08769.1 - 0.023 14.4 0.0 0.048 13.4 0.0 1.5 1 0 0 1 1 1 0 FR47-like protein VIT1 PF01988.14 KLO08771.1 - 4.5e-65 219.1 5.2 5.3e-65 218.8 3.6 1.1 1 0 0 1 1 1 1 VIT family VIT1 PF01988.14 KLO08772.1 - 2.1e-70 236.5 6.1 2.5e-70 236.2 4.3 1.0 1 0 0 1 1 1 1 VIT family Herpes_UL17 PF04559.7 KLO08774.1 - 0.13 10.8 0.3 0.13 10.8 0.2 1.0 1 0 0 1 1 1 0 Herpesvirus UL17 protein HABP4_PAI-RBP1 PF04774.10 KLO08775.1 - 6.5e-06 26.5 1.1 8.5e-06 26.2 0.8 1.3 1 1 0 1 1 1 1 Hyaluronan / mRNA binding family Exo_endo_phos PF03372.18 KLO08776.1 - 4.1e-24 85.8 1.6 4.3e-23 82.5 0.8 2.7 2 1 0 2 2 2 1 Endonuclease/Exonuclease/phosphatase family RhoGAP PF00620.22 KLO08776.1 - 8.5e-11 41.6 0.0 4e-10 39.5 0.0 2.0 2 0 0 2 2 2 1 RhoGAP domain PapD-like PF14874.1 KLO08776.1 - 0.00013 21.8 0.0 0.00023 21.0 0.0 1.4 1 0 0 1 1 1 1 Flagellar-associated PapD-like Motile_Sperm PF00635.21 KLO08776.1 - 0.00062 19.3 0.1 0.0014 18.2 0.1 1.6 1 0 0 1 1 1 1 MSP (Major sperm protein) domain TPR_12 PF13424.1 KLO08777.1 - 3e-06 27.0 2.9 0.26 11.2 0.0 4.3 4 1 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.12 KLO08777.1 - 1.1e-05 24.9 2.7 1.4 9.0 0.0 5.2 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_14 PF13428.1 KLO08777.1 - 1.7e-05 25.0 12.2 1.8 9.4 0.1 5.7 7 0 0 7 7 6 3 Tetratricopeptide repeat TPR_1 PF00515.23 KLO08777.1 - 3.1e-05 23.3 1.4 1.2 8.8 0.0 5.1 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_19 PF14559.1 KLO08777.1 - 0.00015 22.0 6.1 0.41 11.0 0.7 3.6 2 2 0 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.1 KLO08777.1 - 0.00039 20.0 3.3 1.2 8.8 0.1 4.7 3 1 1 4 4 4 1 TPR repeat TPR_20 PF14561.1 KLO08777.1 - 0.00072 19.6 0.4 0.31 11.1 0.0 2.9 2 0 0 2 2 2 1 Tetratricopeptide repeat MF_alpha_N PF05436.6 KLO08777.1 - 0.0074 15.9 0.3 0.019 14.6 0.1 1.7 2 0 0 2 2 2 1 Mating factor alpha precursor N-terminus TPR_16 PF13432.1 KLO08777.1 - 0.065 13.9 3.8 28 5.5 0.0 4.2 4 0 0 4 4 3 0 Tetratricopeptide repeat TPR_8 PF13181.1 KLO08777.1 - 0.065 13.0 0.2 20 5.2 0.0 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat SRP-alpha_N PF04086.8 KLO08777.1 - 0.07 12.5 0.2 0.1 11.9 0.1 1.2 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal TPR_7 PF13176.1 KLO08777.1 - 0.092 12.5 2.4 0.63 9.9 0.0 3.6 4 1 0 4 4 4 0 Tetratricopeptide repeat TPR_10 PF13374.1 KLO08777.1 - 9.5 6.3 11.7 4.7 7.2 0.0 3.9 5 0 0 5 5 4 0 Tetratricopeptide repeat FAD_binding_4 PF01565.18 KLO08778.1 - 2.7e-22 78.7 3.0 2.7e-22 78.7 2.1 1.7 2 0 0 2 2 2 1 FAD binding domain BBE PF08031.7 KLO08778.1 - 2.1e-05 24.3 0.0 4.4e-05 23.3 0.0 1.5 1 0 0 1 1 1 1 Berberine and berberine like FAD_binding_4 PF01565.18 KLO08779.1 - 1.3e-22 79.7 0.6 2e-22 79.1 0.4 1.3 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 KLO08779.1 - 0.00011 22.0 0.0 0.00023 20.9 0.0 1.5 1 0 0 1 1 1 1 Berberine and berberine like XPG_I PF00867.13 KLO08780.1 - 3.6e-26 91.0 0.0 1.2e-25 89.3 0.0 2.0 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.12 KLO08780.1 - 3e-22 78.7 0.0 6.4e-22 77.7 0.0 1.6 1 0 0 1 1 1 1 XPG N-terminal domain UIM PF02809.15 KLO08780.1 - 0.17 11.5 13.8 1.2 8.9 2.9 3.1 1 1 1 2 2 2 0 Ubiquitin interaction motif 5_3_exonuc PF01367.15 KLO08780.1 - 0.21 11.8 0.0 0.21 11.8 0.0 3.0 4 0 0 4 4 4 0 5'-3' exonuclease, C-terminal SAM fold NDUF_B8 PF05821.6 KLO08781.1 - 2.1e-10 40.5 0.0 2.8e-10 40.1 0.0 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase ASHI subunit (CI-ASHI or NDUFB8) Methyltransf_25 PF13649.1 KLO08782.1 - 5.8e-13 49.0 0.0 1.1e-12 48.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KLO08782.1 - 6.7e-13 48.9 0.0 1.2e-12 48.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KLO08782.1 - 1.4e-11 44.9 0.0 2.8e-11 43.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KLO08782.1 - 2.7e-08 34.1 0.0 5e-08 33.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KLO08782.1 - 2.8e-08 33.1 0.0 4.4e-08 32.5 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_26 PF13659.1 KLO08782.1 - 3.3e-08 33.5 0.0 8.9e-08 32.1 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KLO08782.1 - 8.7e-08 32.0 0.0 1.5e-07 31.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KLO08782.1 - 3.3e-07 30.0 0.0 5.9e-07 29.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KLO08782.1 - 2.5e-05 23.7 0.0 4.4e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_4 PF02390.12 KLO08782.1 - 0.00053 19.0 0.0 0.0029 16.7 0.0 1.9 2 0 0 2 2 2 1 Putative methyltransferase CMAS PF02353.15 KLO08782.1 - 0.0028 16.7 0.0 0.0043 16.1 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase FmrO PF07091.6 KLO08782.1 - 0.022 13.7 0.0 0.051 12.5 0.0 1.5 2 0 0 2 2 2 0 Ribosomal RNA methyltransferase (FmrO) FtsJ PF01728.14 KLO08782.1 - 0.076 12.9 0.0 0.17 11.8 0.0 1.5 1 0 0 1 1 1 0 FtsJ-like methyltransferase SH3_9 PF14604.1 KLO08783.1 - 6.7e-15 54.3 0.2 1e-14 53.8 0.1 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 KLO08783.1 - 4.3e-14 51.6 0.4 6.3e-14 51.0 0.2 1.3 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 KLO08783.1 - 5.8e-12 44.9 0.1 1e-11 44.1 0.1 1.3 1 0 0 1 1 1 1 Variant SH3 domain Voldacs PF03517.8 KLO08784.1 - 4.2e-30 104.3 0.3 6e-30 103.8 0.2 1.2 1 0 0 1 1 1 1 Regulator of volume decrease after cellular swelling DREPP PF05558.7 KLO08784.1 - 0.16 11.8 1.0 2.4 7.9 0.1 2.0 1 1 1 2 2 2 0 DREPP plasma membrane polypeptide SMC_Nse1 PF07574.8 KLO08786.1 - 0.094 12.3 0.0 0.16 11.5 0.0 1.3 1 0 0 1 1 1 0 Nse1 non-SMC component of SMC5-6 complex HOOK PF05622.7 KLO08786.1 - 0.2 9.4 3.0 0.28 8.9 2.1 1.1 1 0 0 1 1 1 0 HOOK protein Nup88 PF10168.4 KLO08786.1 - 0.33 8.7 1.7 0.51 8.1 1.2 1.2 1 0 0 1 1 1 0 Nuclear pore component DUF607 PF04678.8 KLO08786.1 - 0.84 9.5 2.0 1.7 8.5 1.4 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF607 IncA PF04156.9 KLO08786.1 - 1 8.9 3.2 0.47 10.0 0.3 1.8 2 0 0 2 2 2 0 IncA protein DUF342 PF03961.8 KLO08786.1 - 3.6 5.8 3.2 5.5 5.2 2.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) NUDIX PF00293.23 KLO08787.1 - 1.6e-16 60.1 0.0 2.6e-16 59.4 0.0 1.2 1 0 0 1 1 1 1 NUDIX domain CAP_N PF01213.14 KLO08788.1 - 0.081 12.1 5.4 0.3 10.3 3.8 2.0 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Phage-A118_gp45 PF10653.4 KLO08788.1 - 0.11 12.3 0.0 0.58 10.0 0.0 2.1 2 0 0 2 2 2 0 Protein gp45 of Bacteriophage A118 Kelch_4 PF13418.1 KLO08789.1 - 9.9e-24 82.8 10.9 2.1e-08 33.8 0.1 6.5 6 0 0 6 6 6 4 Galactose oxidase, central domain Kelch_3 PF13415.1 KLO08789.1 - 4.6e-23 80.7 11.6 1.9e-06 27.8 0.1 6.1 5 0 0 5 5 5 4 Galactose oxidase, central domain Kelch_5 PF13854.1 KLO08789.1 - 1.2e-19 69.7 3.6 1.5e-05 24.7 0.0 6.3 6 0 0 6 6 6 4 Kelch motif Kelch_6 PF13964.1 KLO08789.1 - 6.8e-17 60.8 8.4 1e-05 25.4 0.1 5.8 3 1 2 5 5 5 4 Kelch motif Kelch_2 PF07646.10 KLO08789.1 - 8e-13 47.6 4.1 0.011 15.4 0.0 6.1 6 0 0 6 6 6 3 Kelch motif Kelch_1 PF01344.20 KLO08789.1 - 1.1e-07 31.3 0.0 0.0078 15.7 0.0 4.2 4 0 0 4 4 4 2 Kelch motif CD34_antigen PF06365.7 KLO08789.1 - 0.17 11.5 0.0 0.3 10.7 0.0 1.3 1 0 0 1 1 1 0 CD34/Podocalyxin family MSA-2c PF12238.3 KLO08789.1 - 0.28 10.8 2.9 0.64 9.6 2.0 1.6 1 0 0 1 1 1 0 Merozoite surface antigen 2c PLDc_2 PF13091.1 KLO08790.1 - 0.12 12.1 0.0 0.14 11.8 0.0 1.1 1 0 0 1 1 1 0 PLD-like domain ACBP PF00887.14 KLO08791.1 - 1.1e-28 98.7 0.4 1.3e-28 98.5 0.3 1.1 1 0 0 1 1 1 1 Acyl CoA binding protein DUF3934 PF13070.1 KLO08791.1 - 0.088 13.0 0.1 0.16 12.2 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3934) Glyco_hydro_71 PF03659.9 KLO08791.1 - 0.11 10.9 0.0 0.13 10.7 0.0 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 71 PH PF00169.24 KLO08792.1 - 1.2e-29 102.5 0.0 1.4e-16 60.6 0.1 2.5 2 1 0 2 2 2 2 PH domain PH_11 PF15413.1 KLO08792.1 - 2.7e-15 56.5 8.4 1.5e-07 31.6 1.3 4.2 2 2 0 2 2 2 2 Pleckstrin homology domain PH_8 PF15409.1 KLO08792.1 - 4e-09 36.4 1.3 0.00011 22.1 0.1 2.4 2 0 0 2 2 2 2 Pleckstrin homology domain PH_3 PF14593.1 KLO08792.1 - 9.6e-08 31.8 0.4 0.021 14.7 0.0 3.9 3 1 0 3 3 3 2 PH domain PH_9 PF15410.1 KLO08792.1 - 1.2e-06 28.6 0.3 0.15 12.2 0.2 4.1 3 1 0 3 3 3 1 Pleckstrin homology domain Mcp5_PH PF12814.2 KLO08792.1 - 0.024 14.5 4.3 3.8 7.4 0.0 3.3 3 1 0 3 3 3 0 Meiotic cell cortex C-terminal pleckstrin homology PH_4 PF15404.1 KLO08792.1 - 0.038 13.5 0.0 0.2 11.1 0.0 2.2 2 0 0 2 2 2 0 Pleckstrin homology domain Fungal_trans_2 PF11951.3 KLO08795.1 - 6.1e-31 107.3 0.0 3.6e-29 101.5 0.0 2.1 2 0 0 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.13 KLO08795.1 - 0.00025 20.8 8.5 0.00043 20.1 5.9 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Zn_clus PF00172.13 KLO08797.1 - 0.00032 20.5 6.8 0.00041 20.1 4.7 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 KLO08799.1 - 3.3e-36 124.7 0.4 6.4e-18 64.5 0.0 2.1 2 0 0 2 2 2 2 Fungal specific transcription factor domain Drf_GBD PF06371.8 KLO08801.1 - 2.9e-16 59.3 0.0 9e-13 47.9 0.0 2.2 2 0 0 2 2 2 2 Diaphanous GTPase-binding Domain PI3Ka PF00613.15 KLO08802.1 - 1.4e-52 177.5 0.0 2.2e-52 176.9 0.0 1.3 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PI3_PI4_kinase PF00454.22 KLO08802.1 - 1.9e-41 142.0 0.0 4.8e-40 137.4 0.0 2.3 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PI3K_C2 PF00792.19 KLO08802.1 - 9.2e-40 135.7 0.0 1.6e-39 134.9 0.0 1.4 1 0 0 1 1 1 1 Phosphoinositide 3-kinase C2 C2 PF00168.25 KLO08802.1 - 7e-05 22.6 0.0 0.00022 21.0 0.0 1.9 1 0 0 1 1 1 1 C2 domain Aminotran_3 PF00202.16 KLO08803.1 - 4.4e-44 150.7 0.0 1.1e-43 149.4 0.0 1.6 1 1 0 1 1 1 1 Aminotransferase class-III AAA_26 PF13500.1 KLO08803.1 - 1.4e-29 103.1 0.0 2.6e-29 102.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain CbiA PF01656.18 KLO08803.1 - 0.056 12.8 0.0 0.11 11.9 0.0 1.4 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain RAG2_PHD PF13341.1 KLO08804.1 - 0.00096 19.0 0.1 0.001 18.9 0.0 1.1 1 0 0 1 1 1 1 RAG2 PHD domain NDUFB10 PF10249.4 KLO08804.1 - 0.0016 18.5 0.8 0.0017 18.4 0.5 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase subunit 10 MitoNEET_N PF10660.4 KLO08805.1 - 0.028 14.2 0.1 0.053 13.3 0.1 1.4 1 0 0 1 1 1 0 Iron-containing outer mitochondrial membrane protein N-terminus Aminotran_5 PF00266.14 KLO08806.1 - 8.7e-22 77.3 0.0 1.8e-21 76.2 0.0 1.5 1 1 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.16 KLO08806.1 - 1.2e-08 34.3 0.0 1.8e-08 33.7 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.12 KLO08806.1 - 0.064 12.2 0.0 0.77 8.7 0.0 2.1 2 0 0 2 2 2 0 DegT/DnrJ/EryC1/StrS aminotransferase family Cu-oxidase_2 PF07731.9 KLO08806.1 - 0.12 11.9 2.2 0.17 11.3 0.1 2.0 2 0 0 2 2 2 0 Multicopper oxidase SMN PF06003.7 KLO08809.1 - 0.072 12.1 0.4 0.13 11.3 0.3 1.3 1 0 0 1 1 1 0 Survival motor neuron protein (SMN) Rad21_Rec8_N PF04825.8 KLO08810.1 - 0.14 12.1 0.0 0.26 11.2 0.0 1.4 2 0 0 2 2 2 0 N terminus of Rad21 / Rec8 like protein TRAP_alpha PF03896.11 KLO08811.1 - 0.34 9.8 8.3 0.029 13.3 0.3 2.1 2 0 0 2 2 2 0 Translocon-associated protein (TRAP), alpha subunit SDA1 PF05285.7 KLO08811.1 - 6.6 5.9 23.2 1.6 7.9 3.2 2.2 2 0 0 2 2 2 0 SDA1 F-box-like PF12937.2 KLO08813.1 - 2.4e-07 30.3 0.3 2.4e-07 30.3 0.2 2.9 2 2 0 2 2 2 1 F-box-like LRR_8 PF13855.1 KLO08813.1 - 0.015 15.0 0.0 0.093 12.4 0.0 2.3 2 0 0 2 2 2 0 Leucine rich repeat F-box PF00646.28 KLO08813.1 - 0.14 11.8 2.6 2.5 7.8 1.8 2.9 1 1 0 1 1 1 0 F-box domain E1-E2_ATPase PF00122.15 KLO08815.1 - 2.9e-49 167.1 0.9 7e-48 162.6 0.0 3.0 3 0 0 3 3 3 1 E1-E2 ATPase Hydrolase PF00702.21 KLO08815.1 - 3.1e-37 129.0 1.3 4.4e-37 128.5 0.1 1.9 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HMA PF00403.21 KLO08815.1 - 4.5e-24 84.3 0.9 2.5e-10 40.3 0.3 3.6 3 0 0 3 3 3 3 Heavy-metal-associated domain HAD PF12710.2 KLO08815.1 - 4e-17 63.0 0.0 1.1e-16 61.5 0.0 1.8 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 KLO08815.1 - 0.0025 17.4 0.1 0.0051 16.4 0.1 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Pterin_bind PF00809.17 KLO08816.1 - 0.003 16.9 0.0 0.005 16.2 0.0 1.3 1 0 0 1 1 1 1 Pterin binding enzyme NACHT PF05729.7 KLO08817.1 - 1.7e-16 60.3 0.2 1.4e-11 44.3 0.0 3.0 2 1 0 2 2 2 2 NACHT domain AAA_22 PF13401.1 KLO08817.1 - 8.2e-10 38.9 0.0 0.00013 22.1 0.0 2.9 3 0 0 3 3 3 2 AAA domain AAA_16 PF13191.1 KLO08817.1 - 4.7e-08 33.2 0.0 0.022 14.7 0.0 3.6 2 2 0 2 2 2 2 AAA ATPase domain Arch_ATPase PF01637.13 KLO08817.1 - 5.1e-08 32.9 0.0 3.9e-05 23.4 0.0 2.3 2 0 0 2 2 2 2 Archaeal ATPase AAA PF00004.24 KLO08817.1 - 2.4e-06 27.7 0.0 0.0011 19.1 0.0 2.9 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) NB-ARC PF00931.17 KLO08817.1 - 1.2e-05 24.3 0.0 0.028 13.2 0.0 2.3 2 0 0 2 2 2 2 NB-ARC domain Parvo_NS1 PF01057.12 KLO08817.1 - 0.00064 18.6 0.5 0.31 9.8 0.0 2.3 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 AAA_25 PF13481.1 KLO08817.1 - 0.0049 16.2 1.4 0.55 9.6 0.2 3.2 3 0 0 3 3 3 1 AAA domain AAA_17 PF13207.1 KLO08817.1 - 0.0053 17.5 0.0 0.15 12.8 0.0 3.1 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.17 KLO08817.1 - 0.013 15.7 0.2 0.96 9.6 0.0 2.9 2 0 0 2 2 2 0 RNA helicase DAP3 PF10236.4 KLO08817.1 - 0.037 12.9 0.3 7.6 5.3 0.0 3.6 4 1 0 4 4 4 0 Mitochondrial ribosomal death-associated protein 3 AAA_18 PF13238.1 KLO08817.1 - 0.055 13.7 0.1 0.28 11.4 0.1 2.1 2 1 0 2 2 1 0 AAA domain APS_kinase PF01583.15 KLO08817.1 - 0.057 13.0 0.9 1.6 8.3 0.2 2.5 2 0 0 2 2 2 0 Adenylylsulphate kinase DUF1835 PF08874.5 KLO08817.1 - 0.061 13.2 0.0 0.47 10.3 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1835) AAA_19 PF13245.1 KLO08817.1 - 0.076 12.7 0.0 1 9.1 0.0 2.7 3 0 0 3 3 3 0 Part of AAA domain AAA_33 PF13671.1 KLO08817.1 - 0.14 12.0 0.0 0.53 10.1 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.1 KLO08817.1 - 0.15 11.5 0.3 3 7.3 0.2 2.5 3 0 0 3 3 3 0 AAA domain UQ_con PF00179.21 KLO08818.1 - 2.8e-20 72.1 0.0 5.2e-20 71.3 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UBA PF00627.26 KLO08818.1 - 0.0075 16.0 1.5 0.0075 16.0 1.0 2.0 2 0 0 2 2 2 1 UBA/TS-N domain gpUL132 PF11359.3 KLO08818.1 - 0.47 9.7 5.2 1.2 8.4 1.7 2.5 2 0 0 2 2 2 0 Glycoprotein UL132 DUF2076 PF09849.4 KLO08818.1 - 6.9 6.6 18.3 0.73 9.8 0.9 3.1 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2076) Mito_carr PF00153.22 KLO08819.1 - 6.6e-49 163.5 3.7 3.6e-18 65.0 0.2 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Opy2 PF09463.5 KLO08820.1 - 0.00013 22.0 19.6 0.00021 21.2 13.6 1.4 1 0 0 1 1 1 1 Opy2 protein ABC_tran PF00005.22 KLO08821.1 - 4e-17 62.7 0.0 1e-16 61.4 0.0 1.7 1 1 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 KLO08821.1 - 8.4e-12 45.6 1.7 7.3e-05 22.8 0.0 2.2 1 1 0 2 2 2 2 AAA domain AAA_29 PF13555.1 KLO08821.1 - 4e-05 23.0 0.2 0.00011 21.6 0.1 1.7 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_15 PF13175.1 KLO08821.1 - 4.6e-05 22.6 0.0 0.013 14.5 0.0 2.1 2 0 0 2 2 2 2 AAA ATPase domain AAA_25 PF13481.1 KLO08821.1 - 0.00078 18.8 0.0 0.0014 18.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain SRP54 PF00448.17 KLO08821.1 - 0.0013 18.1 0.0 0.0019 17.6 0.0 1.2 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain DUF258 PF03193.11 KLO08821.1 - 0.0052 15.9 0.0 0.0063 15.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function, DUF258 PduV-EutP PF10662.4 KLO08821.1 - 0.012 15.0 0.1 0.021 14.3 0.1 1.3 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_23 PF13476.1 KLO08821.1 - 0.019 15.2 0.1 0.031 14.5 0.1 1.3 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.1 KLO08821.1 - 0.036 14.9 0.4 0.1 13.4 0.2 1.7 1 1 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.13 KLO08821.1 - 0.038 13.4 0.0 0.067 12.6 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family Zeta_toxin PF06414.7 KLO08821.1 - 0.052 12.6 0.0 0.083 11.9 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin AAA_28 PF13521.1 KLO08821.1 - 0.054 13.4 0.0 0.095 12.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.1 KLO08821.1 - 0.075 13.0 0.1 0.13 12.2 0.1 1.3 1 0 0 1 1 1 0 AAA ATPase domain Miro PF08477.8 KLO08821.1 - 0.078 13.4 0.0 0.14 12.6 0.0 1.4 1 0 0 1 1 1 0 Miro-like protein Dynamin_N PF00350.18 KLO08821.1 - 0.089 12.6 0.1 0.14 12.0 0.0 1.2 1 0 0 1 1 1 0 Dynamin family AAA_14 PF13173.1 KLO08821.1 - 0.099 12.5 0.1 0.28 11.0 0.0 1.8 2 0 0 2 2 2 0 AAA domain SMC_N PF02463.14 KLO08821.1 - 0.1 11.8 0.1 0.57 9.3 0.0 1.9 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain NACHT PF05729.7 KLO08821.1 - 0.12 12.0 0.0 0.29 10.7 0.0 1.6 2 0 0 2 2 2 0 NACHT domain F-box-like PF12937.2 KLO08822.1 - 8.8e-06 25.3 0.3 8.8e-06 25.3 0.2 2.1 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 KLO08822.1 - 5.6e-05 22.6 0.3 0.00016 21.1 0.2 1.9 1 0 0 1 1 1 1 F-box domain Imm18 PF15566.1 KLO08823.1 - 0.068 12.5 0.1 0.12 11.6 0.0 1.5 1 0 0 1 1 1 0 Immunity protein 18 F-box-like PF12937.2 KLO08824.1 - 3.9e-07 29.6 0.9 1.3e-06 28.0 0.6 2.0 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KLO08824.1 - 0.13 11.9 3.4 1.7 8.3 2.4 2.7 1 1 0 1 1 1 0 F-box domain LRR_6 PF13516.1 KLO08824.1 - 0.22 11.6 6.7 11 6.4 0.0 5.3 7 0 0 7 7 7 0 Leucine Rich repeat Glyco_hydro_cc PF11790.3 KLO08825.1 - 0.0053 16.2 0.0 0.0074 15.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core NACHT PF05729.7 KLO08826.1 - 2.2e-13 50.2 0.4 4.3e-09 36.2 0.0 3.8 3 2 0 3 3 3 2 NACHT domain AAA_22 PF13401.1 KLO08826.1 - 2.5e-07 30.8 0.0 0.00043 20.4 0.0 3.6 3 0 0 3 3 3 2 AAA domain AAA_16 PF13191.1 KLO08826.1 - 6.4e-07 29.5 1.2 0.00053 20.0 0.1 4.2 3 2 0 3 3 3 1 AAA ATPase domain AAA PF00004.24 KLO08826.1 - 0.00079 19.6 0.1 0.46 10.6 0.0 3.4 3 2 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) APS_kinase PF01583.15 KLO08826.1 - 0.006 16.2 0.4 0.59 9.7 0.1 2.9 3 0 0 3 3 3 1 Adenylylsulphate kinase Parvo_NS1 PF01057.12 KLO08826.1 - 0.078 11.8 0.1 1.6 7.5 0.0 2.2 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 Torsin PF06309.6 KLO08826.1 - 0.088 12.6 0.0 1.1 9.0 0.0 2.7 2 0 0 2 2 2 0 Torsin DUF2493 PF10686.4 KLO08826.1 - 0.17 11.4 0.1 8.3 6.0 0.0 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2493) Sugar_tr PF00083.19 KLO08828.1 - 1.7e-119 399.3 16.4 2.3e-119 398.9 11.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KLO08828.1 - 1.4e-16 60.1 36.2 2.7e-15 55.9 13.6 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1228 PF06779.9 KLO08828.1 - 1.8 8.6 6.5 0.45 10.5 0.1 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF1228) Cation_ATPase_C PF00689.16 KLO08829.1 - 0.00027 20.5 0.0 0.00031 20.3 0.0 1.1 1 0 0 1 1 1 1 Cation transporting ATPase, C-terminus ATP_bind_3 PF01171.15 KLO08830.1 - 1.1e-17 64.1 0.0 2.3e-17 63.1 0.0 1.5 1 0 0 1 1 1 1 PP-loop family DUF2392 PF10288.4 KLO08830.1 - 0.0049 17.2 0.0 0.012 15.9 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF2392) HIPIP PF01355.12 KLO08830.1 - 0.0064 16.5 2.2 2.1 8.5 0.5 3.1 3 0 0 3 3 3 2 High potential iron-sulfur protein RecR PF02132.10 KLO08830.1 - 0.0087 15.4 1.1 0.0087 15.4 0.8 2.6 4 0 0 4 4 4 1 RecR protein tRNA_Me_trans PF03054.11 KLO08830.1 - 0.023 13.2 0.0 0.037 12.6 0.0 1.3 1 0 0 1 1 1 0 tRNA methyl transferase ThiI PF02568.9 KLO08830.1 - 0.11 11.8 0.0 0.24 10.8 0.0 1.5 1 0 0 1 1 1 0 Thiamine biosynthesis protein (ThiI) TF_Zn_Ribbon PF08271.7 KLO08830.1 - 0.6 9.4 10.0 0.64 9.3 0.1 3.5 3 1 1 4 4 3 0 TFIIB zinc-binding SurE PF01975.12 KLO08831.1 - 9.8e-34 116.3 0.3 1.4e-33 115.8 0.2 1.2 1 0 0 1 1 1 1 Survival protein SurE SurE PF01975.12 KLO08832.1 - 1.4e-30 106.0 1.6 1.7e-30 105.8 0.9 1.4 1 1 0 1 1 1 1 Survival protein SurE UbiA PF01040.13 KLO08833.1 - 1.5e-19 70.2 11.2 1.9e-19 69.9 7.8 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family Cobl PF09469.5 KLO08845.1 - 0.025 14.5 0.4 0.12 12.3 0.3 2.1 1 0 0 1 1 1 0 Cordon-bleu ubiquitin-like domain MamL-1 PF09596.5 KLO08850.1 - 0.11 12.3 1.0 0.27 11.0 0.7 1.6 1 0 0 1 1 1 0 MamL-1 domain DUF4094 PF13334.1 KLO08851.1 - 0.17 12.2 0.7 1.2 9.5 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4094) FlaC_arch PF05377.6 KLO08851.1 - 0.19 11.6 0.8 0.41 10.5 0.6 1.6 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) Phage_tail_2 PF06199.6 KLO08855.1 - 0.13 12.2 0.8 0.89 9.6 0.1 2.3 2 0 0 2 2 2 0 Phage major tail protein 2 p450 PF00067.17 KLO08857.1 - 1.1e-60 205.5 0.0 1.5e-60 205.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 zf-C2H2_4 PF13894.1 KLO08858.1 - 0.6 10.5 4.1 46 4.6 2.9 2.7 1 1 0 1 1 1 0 C2H2-type zinc finger OGFr_III PF04680.8 KLO08858.1 - 5 7.4 10.4 5.7 7.2 1.0 2.8 2 0 0 2 2 2 0 Opioid growth factor receptor repeat zf-C2H2_4 PF13894.1 KLO08859.1 - 0.057 13.7 2.3 1.5 9.2 0.2 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger zf-Di19 PF05605.7 KLO08859.1 - 0.14 12.3 0.4 0.23 11.5 0.3 1.4 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2 PF00096.21 KLO08859.1 - 1.5 9.3 6.8 6.5 7.3 0.2 2.9 2 1 0 2 2 2 0 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 KLO08859.1 - 6.9 7.1 10.0 5.2 7.5 1.4 3.2 3 0 0 3 3 3 0 Zinc-finger double domain p450 PF00067.17 KLO08860.1 - 0.01 14.3 0.0 0.013 14.0 0.0 1.1 1 0 0 1 1 1 0 Cytochrome P450 Paralemmin PF03285.10 KLO08861.1 - 0.0067 15.9 0.0 0.013 15.0 0.0 1.5 1 0 0 1 1 1 1 Paralemmin DUF694 PF05107.7 KLO08861.1 - 0.11 11.7 0.0 0.21 10.7 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF694) zf-C2H2 PF00096.21 KLO08862.1 - 0.0029 17.8 1.9 0.0029 17.8 1.3 2.3 2 0 0 2 2 2 1 Zinc finger, C2H2 type Sgf11 PF08209.6 KLO08862.1 - 0.092 12.0 1.9 0.36 10.1 0.9 2.3 2 0 0 2 2 2 0 Sgf11 (transcriptional regulation protein) zf-C2H2_4 PF13894.1 KLO08862.1 - 1.2 9.6 9.3 0.15 12.4 0.6 3.6 4 0 0 4 4 4 0 C2H2-type zinc finger Tir_receptor_C PF07489.6 KLO08863.1 - 0.24 11.1 6.3 0.36 10.5 4.4 1.2 1 0 0 1 1 1 0 Translocated intimin receptor (Tir) C-terminus SR-25 PF10500.4 KLO08863.1 - 0.25 10.7 3.1 0.37 10.2 2.1 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein p450 PF00067.17 KLO08865.1 - 8.3e-37 126.7 0.1 9.7e-37 126.5 0.1 1.0 1 0 0 1 1 1 1 Cytochrome P450 RRM_1 PF00076.17 KLO08866.1 - 3.4e-12 45.8 0.0 6.1e-12 44.9 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KLO08866.1 - 1.1e-11 44.4 0.0 2.3e-11 43.4 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Rad10 PF03834.9 KLO08867.1 - 5.2e-27 93.3 0.0 8.8e-27 92.6 0.0 1.4 1 0 0 1 1 1 1 Binding domain of DNA repair protein Ercc1 (rad10/Swi10) HHH_5 PF14520.1 KLO08867.1 - 7.4e-07 29.2 0.0 7.3e-06 26.0 0.0 2.3 2 1 0 2 2 2 1 Helix-hairpin-helix domain HHH_2 PF12826.2 KLO08867.1 - 0.0013 18.5 0.0 0.0043 16.9 0.0 1.8 2 0 0 2 2 2 1 Helix-hairpin-helix motif HHH PF00633.18 KLO08867.1 - 0.0021 17.6 0.0 0.0055 16.3 0.0 1.8 1 0 0 1 1 1 1 Helix-hairpin-helix motif HhH-GPD PF00730.20 KLO08867.1 - 0.075 13.3 0.0 0.13 12.5 0.0 1.5 1 0 0 1 1 1 0 HhH-GPD superfamily base excision DNA repair protein HHH_3 PF12836.2 KLO08867.1 - 0.13 12.2 0.0 0.45 10.4 0.0 1.9 2 0 0 2 2 2 0 Helix-hairpin-helix motif HRDC PF00570.18 KLO08867.1 - 0.13 11.9 0.0 0.49 10.1 0.0 1.9 2 0 0 2 2 2 0 HRDC domain DUF605 PF04652.11 KLO08867.1 - 0.29 10.4 9.6 0.39 10.0 6.7 1.2 1 0 0 1 1 1 0 Vta1 like Mito_fiss_reg PF05308.6 KLO08867.1 - 7.5 5.8 10.9 16 4.7 7.5 1.6 1 0 0 1 1 1 0 Mitochondrial fission regulator Lactamase_B PF00753.22 KLO08868.1 - 2.1e-11 43.8 1.6 6.7e-11 42.1 1.1 1.9 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 KLO08868.1 - 5.6e-07 29.2 0.1 9.4e-07 28.5 0.0 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Amidohydro_1 PF01979.15 KLO08869.1 - 1.3e-57 195.9 2.8 1.9e-57 195.4 2.0 1.3 1 0 0 1 1 1 1 Amidohydrolase family Urease_alpha PF00449.15 KLO08869.1 - 2.1e-54 182.8 1.8 2.9e-54 182.3 0.6 1.8 2 0 0 2 2 2 1 Urease alpha-subunit, N-terminal domain Urease_beta PF00699.15 KLO08869.1 - 1.4e-41 140.4 0.2 3.6e-41 139.0 0.2 1.8 1 0 0 1 1 1 1 Urease beta subunit Urease_gamma PF00547.13 KLO08869.1 - 1.1e-38 131.2 0.1 3.1e-38 129.7 0.1 1.9 1 0 0 1 1 1 1 Urease, gamma subunit Amidohydro_5 PF13594.1 KLO08869.1 - 1.2e-05 24.9 3.6 4.1e-05 23.3 2.5 1.9 1 0 0 1 1 1 1 Amidohydrolase DAO PF01266.19 KLO08870.1 - 2.2e-07 30.0 0.0 4e-05 22.6 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 KLO08870.1 - 8.4e-07 28.3 0.0 1.1e-06 27.9 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 KLO08870.1 - 3e-06 27.1 0.0 8.2e-06 25.7 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 KLO08870.1 - 0.0002 21.3 0.0 0.00052 19.9 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.19 KLO08870.1 - 0.00022 20.4 0.0 0.0004 19.5 0.0 1.4 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase ApbA PF02558.11 KLO08870.1 - 0.0044 16.4 0.0 0.012 15.0 0.0 1.7 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA Pyr_redox PF00070.22 KLO08870.1 - 0.011 16.1 0.0 0.03 14.7 0.0 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase PAS_10 PF13596.1 KLO08870.1 - 0.026 14.7 0.5 10 6.4 0.0 3.5 3 1 1 4 4 4 0 PAS domain FAD_binding_2 PF00890.19 KLO08870.1 - 0.028 13.2 0.0 0.044 12.6 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain HI0933_like PF03486.9 KLO08870.1 - 0.14 10.5 0.0 0.24 9.8 0.0 1.3 1 0 0 1 1 1 0 HI0933-like protein zf-MYND PF01753.13 KLO08871.1 - 1.2e-10 41.0 15.8 2e-10 40.3 11.0 1.4 1 0 0 1 1 1 1 MYND finger zf-Mss51 PF13824.1 KLO08871.1 - 8.9e-05 22.2 10.5 0.00023 20.9 7.3 1.7 1 0 0 1 1 1 1 Zinc-finger of mitochondrial splicing suppressor 51 Med16 PF11635.3 KLO08871.1 - 1.6 6.5 3.5 2.1 6.2 2.4 1.1 1 0 0 1 1 1 0 Mediator complex subunit 16 zf-MYND PF01753.13 KLO08872.1 - 8.2e-07 28.7 7.4 1.4e-06 28.0 5.1 1.3 1 0 0 1 1 1 1 MYND finger zf-Mss51 PF13824.1 KLO08872.1 - 0.0026 17.5 4.6 0.0071 16.1 3.2 1.7 1 0 0 1 1 1 1 Zinc-finger of mitochondrial splicing suppressor 51 zf-HIT PF04438.11 KLO08872.1 - 0.73 9.5 5.6 1.1 8.9 3.9 1.3 1 0 0 1 1 1 0 HIT zinc finger zf-C2H2_4 PF13894.1 KLO08874.1 - 0.0057 16.8 8.9 0.019 15.2 1.6 3.0 3 0 0 3 3 3 1 C2H2-type zinc finger zf-H2C2_2 PF13465.1 KLO08874.1 - 0.04 14.2 0.8 0.04 14.2 0.5 2.8 3 0 0 3 3 3 0 Zinc-finger double domain zf-C2H2 PF00096.21 KLO08874.1 - 1.6 9.2 15.9 0.13 12.6 2.4 3.4 3 0 0 3 3 3 0 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.3 KLO08874.1 - 2.9 8.1 5.8 0.6 10.3 0.7 2.4 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-MYND PF01753.13 KLO08875.1 - 4.2e-07 29.7 7.9 4.2e-07 29.7 5.5 1.9 2 0 0 2 2 2 1 MYND finger zf-C2H2 PF00096.21 KLO08876.1 - 0.025 14.8 1.2 0.025 14.8 0.8 2.9 3 0 0 3 3 3 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KLO08876.1 - 0.091 13.1 4.0 0.6 10.5 0.6 2.8 2 0 0 2 2 2 0 C2H2-type zinc finger DUF1936 PF09151.5 KLO08876.1 - 1.9 8.0 4.4 8.7 5.9 3.1 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF1936) zf-MYND PF01753.13 KLO08877.1 - 5.4e-09 35.7 11.9 1.7e-08 34.1 8.2 2.0 1 0 0 1 1 1 1 MYND finger zf-Mss51 PF13824.1 KLO08877.1 - 0.11 12.4 1.5 0.43 10.4 1.1 2.1 1 0 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 zf-MYND PF01753.13 KLO08878.1 - 7e-09 35.4 11.0 1.4e-08 34.4 7.6 1.5 1 0 0 1 1 1 1 MYND finger zf-Mss51 PF13824.1 KLO08878.1 - 0.36 10.7 3.3 0.82 9.5 2.3 1.6 1 0 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 zf-MYND PF01753.13 KLO08879.1 - 6.1e-10 38.8 9.8 1.2e-09 37.8 6.8 1.4 1 0 0 1 1 1 1 MYND finger zf-Mss51 PF13824.1 KLO08879.1 - 0.00034 20.3 1.9 0.00077 19.2 1.3 1.6 1 0 0 1 1 1 1 Zinc-finger of mitochondrial splicing suppressor 51 Ecl1 PF12855.2 KLO08879.1 - 0.3 10.4 3.1 0.62 9.4 2.2 1.6 1 0 0 1 1 1 0 Life-span regulatory factor zf-MYND PF01753.13 KLO08880.1 - 7.9e-10 38.4 14.6 7.9e-10 38.4 10.1 2.1 2 0 0 2 2 2 1 MYND finger Ecl1 PF12855.2 KLO08880.1 - 0.25 10.6 4.0 0.66 9.3 2.8 1.7 1 0 0 1 1 1 0 Life-span regulatory factor zf-Mss51 PF13824.1 KLO08880.1 - 2.6 7.9 7.6 5.3 6.9 5.3 1.5 1 0 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 DUF3133 PF11331.3 KLO08880.1 - 4.2 7.0 9.4 17 5.0 1.4 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF3133) Helicase_C PF00271.26 KLO08881.1 - 2.6e-14 52.8 0.5 1.1e-13 50.7 0.1 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain Transposase_21 PF02992.9 KLO08882.1 - 6.3e-10 38.5 0.0 1.7e-09 37.1 0.0 1.6 2 0 0 2 2 2 1 Transposase family tnp2 Bile_Hydr_Trans PF04775.9 KLO08882.1 - 0.03 14.0 0.0 0.09 12.4 0.0 1.7 2 0 0 2 2 2 0 Acyl-CoA thioester hydrolase/BAAT N-terminal region Pkinase PF00069.20 KLO08884.1 - 1.2e-32 113.1 0.0 1.3e-32 112.9 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KLO08884.1 - 2.8e-32 111.7 0.0 3.5e-32 111.4 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KLO08884.1 - 3.9e-06 26.0 0.0 1.1e-05 24.5 0.0 1.6 1 1 1 2 2 2 1 Kinase-like APH PF01636.18 KLO08884.1 - 0.004 16.9 0.0 0.0061 16.3 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 KLO08884.1 - 0.051 12.6 0.0 0.065 12.2 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 KLO08884.1 - 0.06 12.6 0.0 0.094 12.0 0.0 1.2 1 0 0 1 1 1 0 RIO1 family Myticin-prepro PF10690.4 KLO08885.1 - 0.0069 16.4 0.0 0.011 15.7 0.0 1.3 1 0 0 1 1 1 1 Myticin pre-proprotein from the mussel RuBisCO_small PF00101.15 KLO08885.1 - 0.02 14.6 0.1 0.052 13.3 0.1 1.7 2 0 0 2 2 2 0 Ribulose bisphosphate carboxylase, small chain Pkinase PF00069.20 KLO08886.1 - 7.6e-56 189.1 0.0 6.3e-33 114.0 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 KLO08886.1 - 8.1e-54 182.4 0.0 1.2e-32 113.0 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 KLO08886.1 - 8.7e-06 24.8 0.0 5e-05 22.3 0.0 2.0 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 KLO08886.1 - 2.8e-05 23.9 0.1 0.037 13.7 0.0 2.6 2 0 0 2 2 2 2 Phosphotransferase enzyme family RIO1 PF01163.17 KLO08886.1 - 0.007 15.7 0.0 4.2 6.6 0.0 2.4 2 0 0 2 2 2 2 RIO1 family Kdo PF06293.9 KLO08886.1 - 0.0092 15.0 0.0 0.074 12.1 0.0 2.1 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family WaaY PF06176.6 KLO08886.1 - 0.02 14.1 0.0 0.34 10.0 0.0 2.2 2 0 0 2 2 2 0 Lipopolysaccharide core biosynthesis protein (WaaY) Pkinase_Tyr PF07714.12 KLO08887.1 - 6.6e-36 123.7 0.0 1.9e-35 122.1 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase PF00069.20 KLO08887.1 - 7.8e-36 123.5 0.0 1.3e-35 122.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.18 KLO08887.1 - 0.048 13.3 0.2 0.37 10.4 0.1 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family Pkinase_Tyr PF07714.12 KLO08889.1 - 1.6e-39 135.5 0.0 3.1e-39 134.6 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 KLO08889.1 - 2.4e-35 121.9 0.0 3.5e-35 121.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.1 KLO08889.1 - 0.00063 18.7 0.0 0.00096 18.1 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 KLO08889.1 - 0.00071 18.6 0.0 0.0012 17.9 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KLO08889.1 - 0.0083 15.8 0.1 0.017 14.8 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.17 KLO08889.1 - 0.0087 15.4 0.0 0.018 14.3 0.0 1.5 1 0 0 1 1 1 1 RIO1 family Pkinase PF00069.20 KLO08890.1 - 1e-62 211.6 0.0 8.2e-40 136.5 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 KLO08890.1 - 1.1e-59 201.5 0.0 3.5e-41 141.0 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 KLO08890.1 - 9.2e-07 28.1 0.0 0.00016 20.7 0.0 2.2 2 0 0 2 2 2 2 Kinase-like APH PF01636.18 KLO08890.1 - 2.5e-06 27.3 0.1 0.0028 17.4 0.0 2.3 2 0 0 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.9 KLO08890.1 - 0.00026 20.1 0.0 0.16 10.9 0.0 2.3 2 0 0 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family WaaY PF06176.6 KLO08890.1 - 0.0045 16.2 0.0 0.055 12.6 0.0 2.1 2 0 0 2 2 2 1 Lipopolysaccharide core biosynthesis protein (WaaY) RIO1 PF01163.17 KLO08890.1 - 0.016 14.5 0.0 5.5 6.2 0.0 2.3 2 0 0 2 2 2 0 RIO1 family Cellulose_synt PF03552.9 KLO08896.1 - 3.8 5.6 6.5 18 3.4 4.5 1.9 1 1 0 1 1 1 0 Cellulose synthase BTB PF00651.26 KLO08897.1 - 0.00012 22.0 0.0 0.00019 21.4 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain Tnp_zf-ribbon_2 PF13842.1 KLO08897.1 - 0.018 15.4 1.3 0.045 14.1 0.1 2.1 2 0 0 2 2 2 0 DDE_Tnp_1-like zinc-ribbon BTB PF00651.26 KLO08898.1 - 0.0006 19.7 0.0 0.00099 19.0 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain DZR PF12773.2 KLO08898.1 - 0.068 13.0 0.2 0.12 12.1 0.2 1.3 1 0 0 1 1 1 0 Double zinc ribbon Peptidase_S28 PF05577.7 KLO08900.1 - 1.3e-55 188.7 3.5 2.9e-37 128.3 0.7 2.7 2 1 0 2 2 2 2 Serine carboxypeptidase S28 Choline_sulf_C PF12411.3 KLO08901.1 - 0.022 14.5 0.4 0.056 13.2 0.3 1.6 1 0 0 1 1 1 0 Choline sulfatase enzyme C terminal STE3 PF02076.10 KLO08902.1 - 3.9e-50 170.5 15.1 4.2e-49 167.1 10.5 2.0 1 1 0 1 1 1 1 Pheromone A receptor GLTP PF08718.6 KLO08903.1 - 1e-27 97.0 0.0 1.4e-27 96.6 0.0 1.1 1 0 0 1 1 1 1 Glycolipid transfer protein (GLTP) GvpD PF07088.6 KLO08904.1 - 0.092 11.0 0.0 0.099 10.9 0.0 1.2 1 0 0 1 1 1 0 GvpD gas vesicle protein zf-C2H2 PF00096.21 KLO08905.1 - 3e-13 49.2 9.2 8.2e-07 29.0 1.3 2.1 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 KLO08905.1 - 5.6e-11 42.1 13.5 4e-07 30.0 0.2 3.1 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 KLO08905.1 - 1.5e-09 37.4 7.2 9.7e-05 22.4 0.5 2.1 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2HC_2 PF13913.1 KLO08905.1 - 0.00016 21.1 8.7 0.045 13.4 0.9 2.4 2 1 0 2 2 2 2 zinc-finger of a C2HC-type zf-C2H2_jaz PF12171.3 KLO08905.1 - 0.00057 19.9 4.4 0.0075 16.3 0.4 2.3 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 KLO08905.1 - 0.0006 19.9 2.2 0.02 15.1 0.6 2.3 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-BED PF02892.10 KLO08905.1 - 0.0029 17.3 4.1 0.027 14.2 0.3 2.2 2 0 0 2 2 2 1 BED zinc finger zf-TRAF PF02176.13 KLO08905.1 - 0.012 15.9 1.6 0.016 15.5 1.1 1.2 1 0 0 1 1 1 0 TRAF-type zinc finger Zn-ribbon_8 PF09723.5 KLO08905.1 - 0.036 14.0 1.7 4.8 7.2 0.2 2.2 2 0 0 2 2 2 0 Zinc ribbon domain ADK_lid PF05191.9 KLO08905.1 - 0.052 13.2 1.9 1.3 8.7 0.1 2.3 2 0 0 2 2 2 0 Adenylate kinase, active site lid zf-LYAR PF08790.6 KLO08905.1 - 0.13 12.0 1.1 2.3 7.9 0.0 2.6 2 1 0 2 2 2 0 LYAR-type C2HC zinc finger IBR PF01485.16 KLO08905.1 - 0.13 12.1 1.3 3.3 7.6 0.0 2.1 1 1 1 2 2 2 0 IBR domain zf-C2H2_2 PF12756.2 KLO08905.1 - 0.23 11.5 1.6 0.56 10.3 0.2 1.9 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-UBP PF02148.14 KLO08905.1 - 0.25 11.5 1.7 4.2 7.5 0.0 2.1 1 1 1 2 2 2 0 Zn-finger in ubiquitin-hydrolases and other protein zf-C2H2_6 PF13912.1 KLO08905.1 - 0.41 10.6 3.8 2.7 8.0 0.1 2.5 2 1 0 2 2 2 0 C2H2-type zinc finger FYVE PF01363.16 KLO08905.1 - 0.85 9.5 7.0 2.9 7.8 2.5 2.0 1 1 1 2 2 2 0 FYVE zinc finger Ribosomal_S27 PF01599.14 KLO08905.1 - 8.8 6.2 7.0 27 4.6 0.1 2.2 2 0 0 2 2 2 0 Ribosomal protein S27a Vps51 PF08700.6 KLO08907.1 - 1.7e-23 82.2 1.5 2.3e-23 81.8 1.0 1.2 1 0 0 1 1 1 1 Vps51/Vps67 COG5 PF10392.4 KLO08907.1 - 0.00034 20.5 1.5 0.00051 20.0 1.0 1.2 1 0 0 1 1 1 1 Golgi transport complex subunit 5 Dor1 PF04124.7 KLO08907.1 - 0.00039 18.9 0.5 0.00048 18.6 0.4 1.1 1 0 0 1 1 1 1 Dor1-like family FlgN PF05130.7 KLO08907.1 - 0.068 13.4 0.5 0.1 12.8 0.3 1.2 1 0 0 1 1 1 0 FlgN protein DUF427 PF04248.7 KLO08909.1 - 8.7e-35 118.2 0.0 9.6e-27 92.4 0.0 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF427) RVP_2 PF08284.6 KLO08909.1 - 0.025 14.5 0.0 0.035 14.0 0.0 1.2 1 0 0 1 1 1 0 Retroviral aspartyl protease Methyltransf_2 PF00891.13 KLO08910.1 - 1.2e-30 106.5 0.0 2.6e-30 105.3 0.0 1.5 1 1 0 1 1 1 1 O-methyltransferase Methyltransf_18 PF12847.2 KLO08910.1 - 6.5e-07 29.9 0.0 1.4e-06 28.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 KLO08910.1 - 0.0035 16.3 0.0 0.0064 15.5 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_23 PF13489.1 KLO08910.1 - 0.017 14.8 0.0 0.041 13.6 0.0 1.6 2 0 0 2 2 2 0 Methyltransferase domain MTS PF05175.9 KLO08910.1 - 0.044 13.1 0.0 0.09 12.1 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain Dimerisation PF08100.6 KLO08910.1 - 0.12 12.2 0.1 0.33 10.7 0.1 1.7 1 0 0 1 1 1 0 Dimerisation domain APH PF01636.18 KLO08911.1 - 2.7e-07 30.5 0.0 3.7e-07 30.1 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 KLO08911.1 - 0.14 11.6 0.0 0.22 11.0 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase Ribosomal_L16 PF00252.13 KLO08913.1 - 9.1e-35 119.3 0.1 1.1e-34 119.0 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e PRP3 PF08572.5 KLO08914.1 - 1.1e-64 217.8 12.3 2e-64 217.0 8.5 1.4 1 0 0 1 1 1 1 pre-mRNA processing factor 3 (PRP3) DUF1115 PF06544.7 KLO08914.1 - 3.5e-30 104.2 1.5 1e-29 102.7 0.0 2.5 3 0 0 3 3 3 1 Protein of unknown function (DUF1115) Pkinase_Tyr PF07714.12 KLO08915.1 - 7.7e-43 146.4 0.0 1.1e-42 145.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 KLO08915.1 - 1.4e-37 129.2 0.0 2.3e-37 128.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.18 KLO08915.1 - 0.003 17.3 0.0 0.0068 16.1 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 KLO08915.1 - 0.018 13.9 0.0 0.039 12.7 0.0 1.5 1 0 0 1 1 1 0 Seadornavirus VP7 RIO1 PF01163.17 KLO08915.1 - 0.1 11.9 0.0 0.19 11.0 0.0 1.4 1 0 0 1 1 1 0 RIO1 family F-box-like PF12937.2 KLO08916.1 - 4.6e-10 39.0 0.1 9.7e-10 38.0 0.1 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KLO08916.1 - 1.6e-05 24.4 0.0 6.3e-05 22.5 0.0 2.0 1 0 0 1 1 1 1 F-box domain GSHPx PF00255.14 KLO08917.1 - 1.8e-41 139.8 0.2 2.5e-41 139.4 0.1 1.2 1 0 0 1 1 1 1 Glutathione peroxidase AhpC-TSA PF00578.16 KLO08917.1 - 1.7e-05 24.5 0.1 5.1e-05 22.9 0.1 1.8 1 1 0 1 1 1 1 AhpC/TSA family DUF4174 PF13778.1 KLO08917.1 - 0.00032 20.7 0.0 0.00065 19.7 0.0 1.5 1 1 0 1 1 1 1 Domain of unknown function (DUF4174) Redoxin PF08534.5 KLO08917.1 - 0.0004 19.9 0.1 0.00074 19.0 0.1 1.5 1 1 0 1 1 1 1 Redoxin DUF3133 PF11331.3 KLO08918.1 - 1.4 8.5 10.1 2.7 7.6 7.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3133) Lar_restr_allev PF14354.1 KLO08919.1 - 0.0017 18.6 0.2 0.0094 16.2 0.2 2.1 2 0 0 2 2 2 1 Restriction alleviation protein Lar Zn_clus PF00172.13 KLO08920.1 - 0.00077 19.3 6.7 0.0012 18.6 4.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HlyD PF00529.15 KLO08923.1 - 0.81 8.9 21.4 1.3 8.2 14.8 1.4 1 0 0 1 1 1 0 HlyD family secretion protein Telomerase_RBD PF12009.3 KLO08924.1 - 0.0023 17.8 0.0 0.0029 17.5 0.0 1.2 1 0 0 1 1 1 1 Telomerase ribonucleoprotein complex - RNA binding domain TPR_11 PF13414.1 KLO08926.1 - 3.3e-12 45.8 7.2 3.8e-07 29.6 0.8 2.6 1 1 2 3 3 3 3 TPR repeat TPR_2 PF07719.12 KLO08926.1 - 1.8e-06 27.4 2.1 0.073 13.0 0.0 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.1 KLO08926.1 - 0.00065 19.5 0.5 0.32 10.9 0.0 2.7 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.1 KLO08926.1 - 0.00084 18.9 0.7 17 5.5 0.0 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_19 PF14559.1 KLO08926.1 - 0.0016 18.7 0.3 0.044 14.1 0.1 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.1 KLO08926.1 - 0.0016 19.0 0.2 0.17 12.5 0.0 2.6 3 0 0 3 3 2 1 Tetratricopeptide repeat TPR_9 PF13371.1 KLO08926.1 - 0.0018 18.0 0.0 0.0032 17.2 0.0 1.4 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_14 PF13428.1 KLO08926.1 - 0.0019 18.6 0.0 0.89 10.3 0.0 2.5 1 1 1 2 2 2 2 Tetratricopeptide repeat Clathrin PF00637.15 KLO08926.1 - 0.0023 17.5 0.3 0.0061 16.1 0.1 1.7 1 1 0 1 1 1 1 Region in Clathrin and VPS TPR_1 PF00515.23 KLO08926.1 - 0.012 15.2 3.6 2.6 7.7 0.1 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_20 PF14561.1 KLO08926.1 - 0.013 15.5 3.2 0.05 13.7 0.7 2.8 2 2 0 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.1 KLO08926.1 - 0.072 13.5 0.9 0.53 10.8 0.0 2.8 3 1 0 3 3 2 0 Tetratricopeptide repeat TPR_17 PF13431.1 KLO08926.1 - 0.29 11.4 1.5 3.3 8.1 0.1 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.1 KLO08926.1 - 0.43 10.4 3.0 16 5.5 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat MIT PF04212.13 KLO08926.1 - 0.56 10.1 4.6 3.8 7.4 0.1 2.9 2 1 0 2 2 2 0 MIT (microtubule interacting and transport) domain Phosphonate-bd PF12974.2 KLO08930.1 - 3.8e-06 26.4 0.0 5.9e-06 25.8 0.0 1.4 1 1 0 1 1 1 1 ABC transporter, phosphonate, periplasmic substrate-binding protein NMT1 PF09084.6 KLO08930.1 - 8.7e-06 25.4 0.0 1.9e-05 24.3 0.0 1.7 2 0 0 2 2 2 1 NMT1/THI5 like SBP_bac_3 PF00497.15 KLO08930.1 - 6.1e-05 22.3 0.0 0.00017 20.9 0.0 1.8 2 1 0 2 2 2 1 Bacterial extracellular solute-binding proteins, family 3 NMT1_2 PF13379.1 KLO08930.1 - 0.002 17.5 0.0 0.0029 17.0 0.0 1.2 1 0 0 1 1 1 1 NMT1-like family LysR_substrate PF03466.15 KLO08930.1 - 0.0087 15.1 0.0 0.044 12.8 0.0 1.8 1 1 0 1 1 1 1 LysR substrate binding domain Lipase_3 PF01764.20 KLO08931.1 - 1.2e-07 31.4 0.0 3.5e-07 29.9 0.0 1.8 1 1 0 1 1 1 1 Lipase (class 3) Abhydrolase_5 PF12695.2 KLO08931.1 - 0.031 14.0 0.0 0.063 13.0 0.0 1.5 1 1 0 1 1 1 0 Alpha/beta hydrolase family PGAP1 PF07819.8 KLO08931.1 - 0.076 12.5 0.0 0.36 10.3 0.0 1.9 2 0 0 2 2 2 0 PGAP1-like protein KRTAP7 PF15034.1 KLO08931.1 - 0.43 11.2 4.2 0.35 11.5 0.5 2.3 2 0 0 2 2 2 0 KRTAP type 7 family Metallophos PF00149.23 KLO08932.1 - 2.4e-05 23.8 0.9 0.00088 18.7 0.6 3.0 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase FBPase_2 PF06874.6 KLO08932.1 - 0.033 12.2 0.3 0.059 11.4 0.0 1.5 2 0 0 2 2 2 0 Firmicute fructose-1,6-bisphosphatase Yip1 PF04893.12 KLO08933.1 - 4.7e-14 52.2 16.6 6.9e-14 51.7 11.5 1.2 1 0 0 1 1 1 1 Yip1 domain DUF4199 PF13858.1 KLO08933.1 - 0.0084 16.0 1.8 0.0084 16.0 1.3 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF4199) ATG22 PF11700.3 KLO08934.1 - 1.5e-120 402.9 25.4 1.7e-120 402.7 17.6 1.0 1 0 0 1 1 1 1 Vacuole effluxer Atg22 like TraS PF10624.4 KLO08934.1 - 5.8 6.4 11.5 0.14 11.7 3.0 1.9 2 0 0 2 2 2 0 Plasmid conjugative transfer entry exclusion protein TraS Trehalase PF01204.13 KLO08935.1 - 7.9e-159 529.5 0.0 9.5e-159 529.3 0.0 1.1 1 0 0 1 1 1 1 Trehalase Trehalase_Ca-bi PF07492.6 KLO08935.1 - 1.7e-10 40.0 0.0 3e-10 39.2 0.0 1.4 1 0 0 1 1 1 1 Neutral trehalase Ca2+ binding domain RHH_4 PF13467.1 KLO08935.1 - 0.0082 15.9 0.0 4.7 7.1 0.0 2.8 3 0 0 3 3 3 2 Ribbon-helix-helix domain Nucleoporin_FG PF13634.1 KLO08936.1 - 2.2e-13 50.4 97.0 2.7e-08 34.0 38.5 2.9 1 1 1 2 2 2 2 Nucleoporin FG repeat region DUF342 PF03961.8 KLO08936.1 - 0.019 13.3 0.7 2.1 6.6 0.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF342) AAA_27 PF13514.1 KLO08936.1 - 0.037 11.7 11.4 0.091 10.4 7.9 1.5 1 1 0 1 1 1 0 AAA domain PRP1_N PF06424.7 KLO08936.1 - 0.055 13.7 0.0 0.14 12.4 0.0 1.7 1 0 0 1 1 1 0 PRP1 splicing factor, N-terminal AIP3 PF03915.8 KLO08936.1 - 0.88 8.4 8.6 0.15 10.9 1.7 2.0 1 1 1 2 2 2 0 Actin interacting protein 3 IncA PF04156.9 KLO08936.1 - 0.97 8.9 5.5 0.9 9.1 0.1 2.4 2 1 0 2 2 2 0 IncA protein AATF-Che1 PF13339.1 KLO08936.1 - 5.5 7.1 9.3 6.1e+02 0.5 5.5 2.8 1 1 1 2 2 2 0 Apoptosis antagonizing transcription factor Arrestin_N PF00339.24 KLO08937.1 - 2e-06 27.6 0.1 0.00094 19.0 0.0 3.6 2 1 0 2 2 2 2 Arrestin (or S-antigen), N-terminal domain Arrestin_N PF00339.24 KLO08938.1 - 4.6e-05 23.2 0.1 0.018 14.8 0.0 3.4 2 1 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain Actin PF00022.14 KLO08939.1 - 1.7e-47 161.7 0.0 3.5e-45 154.1 0.0 3.1 1 1 0 1 1 1 1 Actin UPF0197 PF05251.7 KLO08943.1 - 0.021 15.0 1.5 0.083 13.2 0.8 2.2 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0197) DUF3366 PF11846.3 KLO08943.1 - 0.68 9.7 4.2 0.36 10.6 0.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3366) PHD PF00628.24 KLO08947.1 - 3.4e-07 29.8 5.7 9.8e-07 28.3 3.9 1.8 1 1 0 1 1 1 1 PHD-finger C1_1 PF00130.17 KLO08947.1 - 0.067 12.9 10.7 0.15 11.8 3.7 2.3 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) PHD_2 PF13831.1 KLO08947.1 - 0.31 10.4 4.0 1.2 8.5 0.3 2.4 2 0 0 2 2 2 0 PHD-finger zf-PHD-like PF15446.1 KLO08947.1 - 0.32 10.2 4.8 1.1 8.5 3.3 1.8 1 1 0 1 1 1 0 PHD/FYVE-zinc-finger like domain Lipase_GDSL PF00657.17 KLO08948.1 - 4.1e-09 36.6 0.0 7.7e-09 35.7 0.0 1.5 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.1 KLO08948.1 - 2e-08 34.6 0.0 3.4e-08 33.8 0.0 1.4 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family MFS_1 PF07690.11 KLO08949.1 - 1.4e-22 79.9 36.7 1.2e-15 57.1 15.1 2.7 2 1 1 3 3 3 2 Major Facilitator Superfamily DUF2749 PF10907.3 KLO08949.1 - 0.0031 17.3 1.4 0.021 14.6 0.2 3.0 2 0 0 2 2 2 1 Protein of unknown function (DUF2749) MFS_1_like PF12832.2 KLO08949.1 - 0.0078 15.9 3.2 0.29 10.9 0.0 4.0 3 1 1 4 4 4 1 MFS_1 like family OTU PF02338.14 KLO08950.1 - 8e-09 36.1 0.0 1.4e-08 35.3 0.0 1.4 1 0 0 1 1 1 1 OTU-like cysteine protease ubiquitin PF00240.18 KLO08950.1 - 0.013 14.8 0.3 0.046 13.1 0.1 1.9 3 0 0 3 3 3 0 Ubiquitin family zf-C2H2_jaz PF12171.3 KLO08950.1 - 0.031 14.4 0.1 0.058 13.5 0.1 1.5 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 KLO08950.1 - 0.034 14.3 0.0 0.067 13.4 0.0 1.5 1 0 0 1 1 1 0 Zinc-finger of C2H2 type p450 PF00067.17 KLO08951.1 - 1.1e-63 215.3 0.0 1.8e-63 214.6 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 Tom37_C PF11801.3 KLO08952.1 - 5.4e-17 62.1 0.0 5.4e-17 62.1 0.0 2.1 2 1 0 2 2 2 1 Tom37 C-terminal domain Tom37 PF10568.4 KLO08952.1 - 2.5e-14 53.2 0.1 5.5e-14 52.1 0.0 1.6 1 0 0 1 1 1 1 Outer mitochondrial membrane transport complex protein GST_C_2 PF13410.1 KLO08952.1 - 6.7e-08 32.3 0.0 3.2e-07 30.1 0.0 2.1 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 KLO08952.1 - 0.00035 20.9 0.4 0.0012 19.2 0.0 2.3 2 1 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 KLO08952.1 - 0.01 15.7 0.3 0.033 14.1 0.0 2.0 3 0 0 3 3 3 0 Glutathione S-transferase, C-terminal domain GYF PF02213.11 KLO08953.1 - 2.4e-05 23.8 0.1 5.2e-05 22.7 0.1 1.6 1 0 0 1 1 1 1 GYF domain HSD3 PF15244.1 KLO08953.1 - 0.083 12.1 1.7 0.13 11.4 1.2 1.2 1 0 0 1 1 1 0 Hydroxy-steroid dehydrogenase Ydc2-catalyt PF09159.5 KLO08953.1 - 0.17 11.3 6.7 0.037 13.5 2.2 1.6 2 0 0 2 2 2 0 Mitochondrial resolvase Ydc2 / RNA splicing MRS1 SNF2_N PF00176.18 KLO08954.1 - 2.1e-66 223.7 0.0 3e-66 223.2 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Rad54_N PF08658.5 KLO08954.1 - 6.8e-36 123.8 10.7 1.4e-35 122.8 7.4 1.5 1 0 0 1 1 1 1 Rad54 N terminal Helicase_C PF00271.26 KLO08954.1 - 5.6e-14 51.7 0.0 1.2e-13 50.7 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HDA2-3 PF11496.3 KLO08954.1 - 6.1e-10 38.4 0.0 1.8e-09 36.8 0.0 1.8 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 ResIII PF04851.10 KLO08954.1 - 6e-05 22.9 0.0 0.00064 19.6 0.0 2.6 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_22 PF13401.1 KLO08954.1 - 0.045 13.8 0.0 0.67 10.1 0.0 2.7 2 1 0 2 2 2 0 AAA domain PEP_mutase PF13714.1 KLO08956.1 - 1.3e-45 155.5 2.7 1.5e-45 155.2 1.9 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase ICL PF00463.16 KLO08956.1 - 1.4e-18 66.4 0.4 2e-18 65.9 0.3 1.1 1 0 0 1 1 1 1 Isocitrate lyase family Snf7 PF03357.16 KLO08957.1 - 2.2e-21 75.9 4.2 3.2e-21 75.4 2.9 1.2 1 0 0 1 1 1 1 Snf7 FlaC_arch PF05377.6 KLO08957.1 - 0.058 13.2 0.7 7.8 6.4 0.0 3.5 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) PHD PF00628.24 KLO08959.1 - 3.6e-07 29.7 5.5 9e-07 28.4 3.8 1.7 1 1 0 1 1 1 1 PHD-finger C1_1 PF00130.17 KLO08959.1 - 0.011 15.4 3.7 0.011 15.4 2.5 2.2 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Mem_trans PF03547.13 KLO08959.1 - 0.019 13.2 0.8 0.019 13.2 0.6 1.1 1 0 0 1 1 1 0 Membrane transport protein zf-PHD-like PF15446.1 KLO08959.1 - 0.11 11.8 4.5 0.23 10.7 3.0 1.7 1 1 0 1 1 1 0 PHD/FYVE-zinc-finger like domain Tnp_zf-ribbon_2 PF13842.1 KLO08959.1 - 5.7 7.4 8.7 5.3 7.5 3.7 2.3 2 0 0 2 2 2 0 DDE_Tnp_1-like zinc-ribbon Methyltransf_2 PF00891.13 KLO08961.1 - 4.2e-31 107.9 0.0 6.5e-31 107.3 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase FHA PF00498.21 KLO08962.1 - 2.2e-15 56.5 1.8 2.6e-15 56.2 0.0 2.1 2 0 0 2 2 2 1 FHA domain DUF948 PF06103.6 KLO08962.1 - 0.54 10.1 11.3 3 7.7 0.7 3.8 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF948) DUF1878 PF08963.5 KLO08962.1 - 1.5 9.0 8.7 7.2 6.8 2.2 3.6 3 1 1 4 4 4 0 Protein of unknown function (DUF1878) FAD_binding_7 PF03441.9 KLO08963.1 - 1.3e-55 188.6 2.4 1.9e-55 188.0 1.6 1.2 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.13 KLO08963.1 - 1.3e-22 80.2 0.0 2.4e-22 79.4 0.0 1.4 1 0 0 1 1 1 1 DNA photolyase CobT PF06213.7 KLO08964.1 - 0.35 9.9 7.1 0.026 13.6 1.6 1.4 2 0 0 2 2 2 0 Cobalamin biosynthesis protein CobT UCH PF00443.24 KLO08966.1 - 4.4e-40 137.4 4.3 9.4e-40 136.4 1.3 2.1 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 KLO08966.1 - 5.7e-25 88.3 1.3 1.1e-24 87.4 0.9 1.5 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase ubiquitin PF00240.18 KLO08966.1 - 4.7e-11 41.9 0.1 1.3e-10 40.4 0.0 1.7 1 0 0 1 1 1 1 Ubiquitin family DUSP PF06337.7 KLO08966.1 - 1.4e-09 38.1 0.2 0.00026 21.3 0.0 3.9 4 0 0 4 4 4 2 DUSP domain Rad60-SLD PF11976.3 KLO08966.1 - 0.0058 16.2 0.1 0.013 15.1 0.1 1.6 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like zf-RanBP PF00641.13 KLO08966.1 - 0.011 14.8 1.3 0.011 14.8 0.9 2.8 3 0 0 3 3 3 0 Zn-finger in Ran binding protein and others Gaa1 PF04114.9 KLO08967.1 - 7.5e-68 229.4 4.3 7.5e-68 229.4 3.0 2.8 1 1 1 2 2 2 2 Gaa1-like, GPI transamidase component WD40 PF00400.27 KLO08972.1 - 5e-48 159.3 6.2 1.4e-11 43.8 0.0 5.9 5 0 0 5 5 5 4 WD domain, G-beta repeat NACHT PF05729.7 KLO08972.1 - 1.9e-08 34.1 0.0 1.9e-05 24.4 0.0 2.7 2 0 0 2 2 2 2 NACHT domain AAA_16 PF13191.1 KLO08972.1 - 1.5e-06 28.3 0.0 8.1e-06 25.9 0.0 2.3 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 KLO08972.1 - 1.5e-05 25.1 0.0 8.6e-05 22.6 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA PF00004.24 KLO08972.1 - 3.4e-05 24.0 0.0 0.00063 19.9 0.0 2.8 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.1 KLO08972.1 - 0.0048 16.3 0.2 0.083 12.2 0.2 2.5 2 1 0 2 2 2 1 AAA domain AAA_14 PF13173.1 KLO08972.1 - 0.0072 16.2 0.0 3.5 7.5 0.0 2.7 2 0 0 2 2 2 1 AAA domain PD40 PF07676.7 KLO08972.1 - 0.012 15.3 0.3 14 5.4 0.0 4.3 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat Zeta_toxin PF06414.7 KLO08972.1 - 0.014 14.5 0.0 0.03 13.4 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin NB-ARC PF00931.17 KLO08972.1 - 0.017 14.0 0.0 0.12 11.2 0.0 2.0 2 0 0 2 2 2 0 NB-ARC domain DUF835 PF05763.7 KLO08972.1 - 0.021 14.3 0.0 0.2 11.1 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF835) RNA_helicase PF00910.17 KLO08972.1 - 0.03 14.5 0.1 0.15 12.2 0.0 2.1 2 0 0 2 2 2 0 RNA helicase Gmad1 PF10647.4 KLO08972.1 - 0.033 13.6 0.4 0.059 12.7 0.2 1.3 1 0 0 1 1 1 0 Lipoprotein LpqB beta-propeller domain FtsK_SpoIIIE PF01580.13 KLO08972.1 - 0.047 13.1 0.0 0.45 9.9 0.0 2.4 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_18 PF13238.1 KLO08972.1 - 0.048 13.9 0.1 0.37 11.1 0.0 2.5 3 0 0 3 3 3 0 AAA domain AAA_17 PF13207.1 KLO08972.1 - 0.065 14.0 1.0 0.27 12.0 0.0 2.7 3 0 0 3 3 1 0 AAA domain KAP_NTPase PF07693.9 KLO08972.1 - 9.6 5.0 7.6 2 7.3 0.6 2.6 2 1 0 3 3 3 0 KAP family P-loop domain F-box-like PF12937.2 KLO08976.1 - 5.7e-06 25.9 0.1 1.3e-05 24.7 0.0 1.7 1 0 0 1 1 1 1 F-box-like DUF3930 PF13067.1 KLO08976.1 - 0.21 11.4 1.5 24 4.8 0.6 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3930) F-box-like PF12937.2 KLO08977.1 - 0.00039 20.0 0.0 0.00099 18.7 0.0 1.7 1 0 0 1 1 1 1 F-box-like Phosphodiest PF01663.17 KLO08978.1 - 5.7e-74 249.6 1.1 7.1e-74 249.3 0.8 1.1 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Pkinase PF00069.20 KLO08979.1 - 6.6e-26 91.0 0.0 1.3e-25 90.0 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KLO08979.1 - 2.2e-10 40.0 0.0 3.4e-10 39.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 KLO08979.1 - 0.016 14.9 0.2 0.057 13.1 0.1 1.8 2 1 0 2 2 2 0 Phosphotransferase enzyme family Choline_kinase PF01633.15 KLO08979.1 - 0.073 12.6 0.1 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase PIP49_C PF12260.3 KLO08979.1 - 0.15 11.5 0.0 0.27 10.6 0.0 1.3 1 0 0 1 1 1 0 Protein-kinase domain of FAM69 adh_short PF00106.20 KLO08980.1 - 2.9e-18 66.3 0.2 1e-17 64.5 0.0 1.8 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 KLO08980.1 - 8.9e-07 28.7 0.0 1.8e-06 27.7 0.0 1.5 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 KLO08980.1 - 4.3e-06 26.3 0.0 6.4e-06 25.7 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short_C2 PF13561.1 KLO08980.1 - 0.00013 21.8 0.0 0.0002 21.2 0.0 1.4 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 KLO08980.1 - 0.0014 18.6 0.0 0.0023 17.9 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 KLO08980.1 - 0.037 12.9 0.2 0.11 11.4 0.1 1.7 1 1 0 1 1 1 0 Male sterility protein Shikimate_DH PF01488.15 KLO08980.1 - 0.084 12.9 0.0 0.15 12.1 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase adh_short PF00106.20 KLO08981.1 - 7.9e-20 71.4 0.0 1.8e-19 70.3 0.0 1.5 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 KLO08981.1 - 3.1e-07 30.2 0.2 8.7e-07 28.7 0.1 1.7 1 1 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 KLO08981.1 - 6.3e-06 26.1 0.1 1.2e-05 25.2 0.0 1.4 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 KLO08981.1 - 4.2e-05 23.0 0.0 0.00035 20.0 0.0 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 KLO08981.1 - 6e-05 23.1 0.1 0.0002 21.3 0.0 1.9 2 0 0 2 2 2 1 NADH(P)-binding Shikimate_DH PF01488.15 KLO08981.1 - 0.0064 16.5 0.1 0.012 15.6 0.1 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase AAA_22 PF13401.1 KLO08981.1 - 0.028 14.5 0.1 2.4 8.2 0.0 2.3 2 0 0 2 2 2 0 AAA domain Polysacc_synt_2 PF02719.10 KLO08981.1 - 0.035 12.9 0.1 0.05 12.5 0.1 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.7 KLO08981.1 - 0.11 11.3 0.2 0.42 9.4 0.1 1.9 1 1 0 1 1 1 0 Male sterility protein adh_short PF00106.20 KLO08982.1 - 7.7e-21 74.7 0.0 1.3e-20 74.0 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KLO08982.1 - 2.2e-09 37.2 0.0 3.2e-09 36.6 0.0 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 KLO08982.1 - 1e-05 25.6 0.1 1.7e-05 24.9 0.1 1.3 1 0 0 1 1 1 1 NADH(P)-binding adh_short_C2 PF13561.1 KLO08982.1 - 4.6e-05 23.3 0.0 6.4e-05 22.8 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 KLO08982.1 - 0.0025 17.2 0.0 0.0037 16.7 0.0 1.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Shikimate_DH PF01488.15 KLO08982.1 - 0.0045 17.0 0.1 0.011 15.7 0.0 1.6 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase Saccharop_dh PF03435.13 KLO08982.1 - 0.017 14.1 0.2 0.029 13.3 0.1 1.3 1 0 0 1 1 1 0 Saccharopine dehydrogenase Polysacc_synt_2 PF02719.10 KLO08982.1 - 0.018 13.9 0.1 0.023 13.6 0.1 1.1 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein NmrA PF05368.8 KLO08982.1 - 0.089 12.0 0.3 0.14 11.3 0.2 1.2 1 0 0 1 1 1 0 NmrA-like family 3Beta_HSD PF01073.14 KLO08982.1 - 0.15 10.7 0.0 0.21 10.2 0.0 1.1 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.20 KLO08983.1 - 2.5e-19 69.8 0.0 3.8e-19 69.2 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KLO08983.1 - 6.2e-09 35.7 0.0 9.2e-09 35.2 0.0 1.3 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 KLO08983.1 - 3.5e-05 23.7 0.0 4.9e-05 23.2 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 KLO08983.1 - 0.00077 19.5 0.1 0.0014 18.6 0.0 1.4 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 KLO08983.1 - 0.002 17.6 0.1 0.011 15.1 0.0 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Shikimate_DH PF01488.15 KLO08983.1 - 0.0032 17.5 0.0 0.0055 16.8 0.0 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Polysacc_synt_2 PF02719.10 KLO08983.1 - 0.042 12.7 0.1 0.061 12.2 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Luciferase_cat PF10285.4 KLO08983.1 - 0.05 12.7 0.0 0.069 12.3 0.0 1.2 1 0 0 1 1 1 0 Luciferase catalytic domain DHQS PF01959.11 KLO08983.1 - 0.073 11.7 0.1 0.11 11.2 0.1 1.1 1 0 0 1 1 1 0 3-dehydroquinate synthase (EC 4.6.1.3) QRPTase_C PF01729.14 KLO08983.1 - 0.097 12.1 0.0 0.14 11.6 0.0 1.2 1 0 0 1 1 1 0 Quinolinate phosphoribosyl transferase, C-terminal domain Saccharop_dh PF03435.13 KLO08983.1 - 0.1 11.5 0.1 0.15 10.9 0.1 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase NAD_binding_4 PF07993.7 KLO08983.1 - 0.14 11.0 0.1 0.23 10.3 0.1 1.6 1 1 0 1 1 1 0 Male sterility protein DPBB_1 PF03330.13 KLO08985.1 - 2.5e-06 27.3 0.6 4.1e-05 23.5 0.1 2.7 1 1 1 2 2 2 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel DUF3421 PF11901.3 KLO08987.1 - 0.073 12.8 0.0 1.7 8.4 0.0 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF3421) IncA PF04156.9 KLO08987.1 - 0.27 10.7 6.0 0.63 9.5 4.1 1.5 1 0 0 1 1 1 0 IncA protein DUF1676 PF07898.8 KLO08988.1 - 0.44 10.8 1.2 0.91 9.8 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1676) Sugar_tr PF00083.19 KLO08989.1 - 5.5e-36 124.1 22.1 6.9e-36 123.7 15.3 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KLO08989.1 - 7.8e-33 113.6 27.4 1.1e-32 113.1 19.0 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_1_like PF12832.2 KLO08989.1 - 7.5e-05 22.4 1.2 0.4 10.5 0.0 2.6 2 0 0 2 2 2 2 MFS_1 like family GNAT_acetyltr_2 PF13718.1 KLO08990.1 - 6.2e-79 263.8 0.0 1.1e-78 263.1 0.0 1.4 1 0 0 1 1 1 1 GNAT acetyltransferase 2 Helicase_RecD PF05127.9 KLO08990.1 - 1.5e-65 220.1 0.0 5e-65 218.4 0.0 1.9 2 0 0 2 2 2 1 Helicase DUF1726 PF08351.6 KLO08990.1 - 3.4e-39 132.4 0.4 7.7e-39 131.2 0.0 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF1726) tRNA_bind_2 PF13725.1 KLO08990.1 - 2.8e-33 114.0 0.4 1e-32 112.2 0.3 2.0 1 0 0 1 1 1 1 Possible tRNA binding domain Acetyltransf_7 PF13508.1 KLO08990.1 - 0.0045 17.1 0.0 0.042 14.0 0.0 2.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain CoA_binding_2 PF13380.1 KLO08991.1 - 1.8e-22 79.6 0.0 3e-22 78.9 0.0 1.3 1 0 0 1 1 1 1 CoA binding domain CoA_binding PF02629.14 KLO08991.1 - 7.3e-06 26.4 0.0 1.6e-05 25.3 0.0 1.6 1 0 0 1 1 1 1 CoA binding domain DUF2881 PF11087.3 KLO08991.1 - 0.057 12.8 0.7 3.9 7.0 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF2881) Pex24p PF06398.6 KLO08992.1 - 5.8e-35 120.7 1.4 7.4e-35 120.3 1.0 1.1 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin adh_short PF00106.20 KLO08994.1 - 1.2e-21 77.3 0.1 2.2e-21 76.4 0.1 1.4 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 KLO08994.1 - 6e-10 39.0 0.1 1.2e-09 38.0 0.0 1.5 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 KLO08994.1 - 3.3e-08 33.2 0.6 2.4e-07 30.4 0.4 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 KLO08994.1 - 2.8e-06 27.4 0.5 6.2e-06 26.3 0.2 1.6 2 0 0 2 2 2 1 NADH(P)-binding NAD_binding_4 PF07993.7 KLO08994.1 - 1.1e-05 24.5 0.9 2.9e-05 23.1 0.6 1.6 1 1 0 1 1 1 1 Male sterility protein adh_short_C2 PF13561.1 KLO08994.1 - 1.9e-05 24.5 0.2 2.5e-05 24.1 0.1 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase QRPTase_C PF01729.14 KLO08994.1 - 0.0066 15.9 0.1 0.012 15.1 0.0 1.4 1 0 0 1 1 1 1 Quinolinate phosphoribosyl transferase, C-terminal domain NmrA PF05368.8 KLO08994.1 - 0.024 13.9 0.4 1.1 8.4 0.2 2.1 2 0 0 2 2 2 0 NmrA-like family THF_DHG_CYH_C PF02882.14 KLO08994.1 - 0.067 12.2 0.0 0.13 11.3 0.0 1.4 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain 3Beta_HSD PF01073.14 KLO08994.1 - 0.1 11.2 0.2 0.15 10.7 0.1 1.5 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.20 KLO08995.1 - 2.7e-21 76.2 0.0 5.8e-21 75.1 0.0 1.5 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 KLO08995.1 - 1.5e-09 37.7 0.0 2.2e-09 37.2 0.0 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 KLO08995.1 - 3.3e-06 27.2 0.2 1.6e-05 25.0 0.1 1.9 2 0 0 2 2 2 1 NADH(P)-binding adh_short_C2 PF13561.1 KLO08995.1 - 4.5e-06 26.6 0.0 3e-05 23.9 0.0 1.9 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 KLO08995.1 - 2.4e-05 23.8 0.0 6e-05 22.5 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 KLO08995.1 - 0.00073 18.5 0.0 0.0011 17.9 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Shikimate_DH PF01488.15 KLO08995.1 - 0.011 15.8 0.1 0.02 14.9 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase SBP_bac_3 PF00497.15 KLO08995.1 - 0.025 13.8 0.0 0.036 13.3 0.0 1.2 1 0 0 1 1 1 0 Bacterial extracellular solute-binding proteins, family 3 NAD_binding_4 PF07993.7 KLO08995.1 - 0.034 13.0 0.1 0.066 12.1 0.1 1.6 1 1 0 1 1 1 0 Male sterility protein GATase_7 PF13537.1 KLO08995.1 - 0.074 12.7 0.0 0.17 11.5 0.0 1.6 1 0 0 1 1 1 0 Glutamine amidotransferase domain 3Beta_HSD PF01073.14 KLO08995.1 - 0.1 11.2 0.0 0.15 10.7 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family TPR_12 PF13424.1 KLO08996.1 - 1.9e-25 88.5 18.9 3.4e-08 33.2 0.4 4.6 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_10 PF13374.1 KLO08996.1 - 3.6e-22 77.5 29.0 0.00053 19.8 0.5 7.4 7 0 0 7 7 7 5 Tetratricopeptide repeat Apc5 PF12862.2 KLO08996.1 - 3.4e-12 46.0 22.2 1 9.2 0.1 8.3 2 1 6 8 8 8 5 Anaphase-promoting complex subunit 5 TPR_11 PF13414.1 KLO08996.1 - 2e-10 40.1 12.8 0.0018 17.8 0.1 5.6 3 1 2 5 5 5 3 TPR repeat AAA_16 PF13191.1 KLO08996.1 - 8.9e-09 35.5 2.5 1.8e-08 34.5 0.0 2.7 2 1 0 2 2 2 1 AAA ATPase domain TPR_2 PF07719.12 KLO08996.1 - 9.9e-07 28.2 4.6 6.7 6.8 0.0 6.8 7 0 0 7 7 7 0 Tetratricopeptide repeat DUF3856 PF12968.2 KLO08996.1 - 2.9e-05 23.9 16.6 0.029 14.2 1.3 4.1 1 1 2 3 3 3 3 Domain of Unknown Function (DUF3856) TPR_8 PF13181.1 KLO08996.1 - 4.5e-05 22.9 1.5 6.6 6.7 0.1 6.8 7 0 0 7 7 7 0 Tetratricopeptide repeat NACHT PF05729.7 KLO08996.1 - 0.00064 19.4 0.0 0.0017 17.9 0.0 1.8 1 0 0 1 1 1 1 NACHT domain NPV_P10 PF05531.7 KLO08996.1 - 0.00067 19.8 0.8 0.23 11.7 0.2 3.6 3 0 0 3 3 2 1 Nucleopolyhedrovirus P10 protein AAA_19 PF13245.1 KLO08996.1 - 0.00074 19.2 0.8 0.003 17.2 0.0 2.4 2 0 0 2 2 2 1 Part of AAA domain WASH_WAHD PF11945.3 KLO08996.1 - 0.0011 18.3 0.1 0.0025 17.1 0.0 1.5 1 0 0 1 1 1 1 WAHD domain of WASH complex AAA_22 PF13401.1 KLO08996.1 - 0.0053 16.8 0.2 0.035 14.2 0.0 2.5 3 0 0 3 3 1 1 AAA domain dCMP_cyt_deam_2 PF08211.6 KLO08996.1 - 0.01 15.8 2.0 1.2e+02 2.7 0.0 5.2 2 2 3 5 5 5 0 Cytidine and deoxycytidylate deaminase zinc-binding region AAA PF00004.24 KLO08996.1 - 0.013 15.7 0.0 0.037 14.2 0.0 1.9 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Reo_sigmaC PF04582.7 KLO08996.1 - 0.014 14.6 6.1 0.68 9.0 0.1 3.5 2 1 0 3 3 3 0 Reovirus sigma C capsid protein TIP49 PF06068.8 KLO08996.1 - 0.044 12.4 0.0 0.075 11.7 0.0 1.3 1 0 0 1 1 1 0 TIP49 C-terminus Rapsyn_N PF10579.4 KLO08996.1 - 0.075 12.8 0.2 21 5.0 0.0 4.0 4 1 1 5 5 4 0 Rapsyn N-terminal myristoylation and linker region DASH_Dam1 PF08653.5 KLO08996.1 - 0.12 12.1 14.7 24 4.7 0.0 7.3 7 1 1 8 8 8 0 DASH complex subunit Dam1 NTPase_1 PF03266.10 KLO08996.1 - 0.12 12.0 0.0 0.25 11.0 0.0 1.5 1 0 0 1 1 1 0 NTPase AAA_18 PF13238.1 KLO08996.1 - 0.15 12.3 0.0 0.64 10.3 0.0 2.1 2 0 0 2 2 1 0 AAA domain AAA_17 PF13207.1 KLO08996.1 - 0.18 12.6 0.0 0.58 10.9 0.0 2.0 1 0 0 1 1 1 0 AAA domain DUF2783 PF10932.3 KLO08996.1 - 0.36 10.3 10.7 4.3 6.8 0.4 3.9 3 1 0 3 3 3 0 Protein of unknown function (DUF2783) Rootletin PF15035.1 KLO08996.1 - 0.39 10.6 8.0 0.5 10.3 0.1 3.5 2 1 2 4 4 4 0 Ciliary rootlet component, centrosome cohesion HR1 PF02185.11 KLO08996.1 - 0.45 10.3 6.8 8.2 6.2 0.1 4.0 3 0 0 3 3 3 0 Hr1 repeat DUF2077 PF09850.4 KLO08996.1 - 1.4 8.3 8.7 7.9 5.8 0.2 3.8 3 1 0 4 4 4 0 Uncharacterized protein conserved in bacteria (DUF2077) TPR_7 PF13176.1 KLO08996.1 - 4.3 7.3 8.7 29 4.7 0.0 5.6 6 0 0 6 6 6 0 Tetratricopeptide repeat DUF3584 PF12128.3 KLO08996.1 - 6.7 3.8 11.6 0.1 9.8 0.5 2.5 3 1 0 3 3 3 0 Protein of unknown function (DUF3584) MEF2_binding PF09047.5 KLO08997.1 - 0.15 11.7 0.5 0.25 11.0 0.3 1.4 1 0 0 1 1 1 0 MEF2 binding DUF1601 PF07671.6 KLO08999.1 - 0.086 12.4 0.0 0.15 11.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1601) Sigma70_ner PF04546.8 KLO09000.1 - 0.045 13.3 0.7 0.055 13.0 0.5 1.1 1 0 0 1 1 1 0 Sigma-70, non-essential region DUF2457 PF10446.4 KLO09000.1 - 0.062 12.0 9.5 0.068 11.8 6.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) BTV_NS2 PF04514.7 KLO09000.1 - 0.15 10.9 0.9 0.18 10.6 0.6 1.1 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 PBP1_TM PF14812.1 KLO09000.1 - 1.7 9.0 7.6 2.8 8.3 5.2 1.4 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Nucleoplasmin PF03066.10 KLO09000.1 - 1.9 8.0 9.4 2.6 7.5 6.5 1.2 1 0 0 1 1 1 0 Nucleoplasmin CENP-B_dimeris PF09026.5 KLO09000.1 - 4 7.7 10.8 5.9 7.2 7.5 1.2 1 0 0 1 1 1 0 Centromere protein B dimerisation domain MFS_1 PF07690.11 KLO09001.1 - 1.1e-18 67.0 49.9 4.7e-11 41.9 13.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1228 PF06779.9 KLO09001.1 - 0.026 14.5 2.4 0.34 10.9 0.2 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1228) ATP-synt_10 PF05176.9 KLO09002.1 - 1.8e-61 207.6 0.0 2.2e-61 207.3 0.0 1.1 1 0 0 1 1 1 1 ATP10 protein MFS_1 PF07690.11 KLO09003.1 - 1.4e-21 76.5 52.7 6.6e-13 48.0 16.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1228 PF06779.9 KLO09003.1 - 0.0064 16.4 4.0 0.086 12.8 0.4 2.8 2 0 0 2 2 2 2 Protein of unknown function (DUF1228) HLH PF00010.21 KLO09004.1 - 9.6e-11 41.2 0.1 4.5e-10 39.0 0.0 2.2 3 0 0 3 3 3 1 Helix-loop-helix DNA-binding domain AAA_35 PF14516.1 KLO09004.1 - 0.61 8.6 7.1 1 7.9 5.0 1.2 1 0 0 1 1 1 0 AAA-like domain HAUS2 PF15003.1 KLO09004.1 - 2.3 7.2 10.4 4.6 6.2 1.4 2.4 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 2 TPT PF03151.11 KLO09005.1 - 3.5e-23 81.9 10.2 3.5e-23 81.9 7.1 2.0 2 0 0 2 2 2 1 Triose-phosphate Transporter family EamA PF00892.15 KLO09005.1 - 0.0026 17.7 25.0 0.15 12.1 4.6 2.3 2 0 0 2 2 2 2 EamA-like transporter family UAA PF08449.6 KLO09005.1 - 0.018 13.9 13.2 0.043 12.7 9.1 1.6 1 1 0 1 1 1 0 UAA transporter family DUF563 PF04577.9 KLO09006.1 - 1.7e-07 31.3 0.0 3.5e-07 30.3 0.0 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF563) adh_short PF00106.20 KLO09007.1 - 1.4e-18 67.3 0.4 1.9e-18 66.9 0.3 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KLO09007.1 - 2.8e-16 60.0 0.1 4.6e-16 59.3 0.1 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KLO09007.1 - 7.7e-05 22.4 0.1 0.00012 21.7 0.1 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 KLO09007.1 - 9.5e-05 21.9 0.0 0.00016 21.2 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 KLO09007.1 - 0.034 14.1 0.0 0.083 12.8 0.0 1.6 2 1 0 2 2 2 0 NADH(P)-binding DUF1776 PF08643.5 KLO09007.1 - 0.07 12.2 0.0 0.089 11.9 0.0 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) adh_short PF00106.20 KLO09008.1 - 9.7e-19 67.8 0.8 1.5e-18 67.2 0.5 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KLO09008.1 - 1.1e-11 45.0 0.1 3e-11 43.5 0.0 1.7 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KLO09008.1 - 5.1e-06 26.2 0.2 8.7e-06 25.5 0.1 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 KLO09008.1 - 0.0055 16.1 0.5 0.01 15.3 0.3 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.3 KLO09008.1 - 0.17 11.6 1.6 0.79 9.5 0.0 2.8 3 0 0 3 3 3 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase RNA_pol_L_2 PF13656.1 KLO09009.1 - 1.1e-20 72.8 0.0 1.5e-20 72.3 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.19 KLO09009.1 - 7.7e-14 50.5 0.0 1.1e-13 50.1 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Ribosomal_L18e PF00828.14 KLO09010.1 - 2e-35 121.9 0.1 2.7e-35 121.5 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L18e/L15 RRM_1 PF00076.17 KLO09011.1 - 5.1e-10 38.8 0.0 8.5e-10 38.1 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KLO09011.1 - 7.8e-09 35.3 0.0 1.5e-08 34.5 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Smg4_UPF3 PF03467.10 KLO09011.1 - 0.00034 20.6 0.0 0.00066 19.7 0.0 1.4 1 0 0 1 1 1 1 Smg-4/UPF3 family FoP_duplication PF13865.1 KLO09011.1 - 0.019 15.4 0.1 0.048 14.1 0.1 1.8 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 PH_9 PF15410.1 KLO09013.1 - 0.00081 19.5 0.0 0.00094 19.3 0.0 1.3 1 0 0 1 1 1 1 Pleckstrin homology domain PH PF00169.24 KLO09013.1 - 0.028 14.6 0.0 0.043 14.0 0.0 1.5 1 1 0 1 1 1 0 PH domain Macoilin PF09726.4 KLO09013.1 - 0.65 8.2 2.8 0.68 8.1 1.9 1.0 1 0 0 1 1 1 0 Transmembrane protein Metallophos PF00149.23 KLO09015.1 - 2.8e-44 150.9 0.1 3.5e-44 150.6 0.1 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase CBM_1 PF00734.13 KLO09016.1 - 6.8e-11 41.6 16.2 6.8e-11 41.6 11.2 2.2 2 0 0 2 2 2 1 Fungal cellulose binding domain DUF4215 PF13948.1 KLO09016.1 - 0.091 12.9 0.7 0.19 11.9 0.5 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4215) Sec23_trunk PF04811.10 KLO09017.1 - 5.1e-72 242.1 0.0 7.6e-72 241.5 0.0 1.2 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.10 KLO09017.1 - 1.8e-32 110.7 0.2 3.3e-32 109.9 0.2 1.4 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Sec23_BS PF08033.7 KLO09017.1 - 2.1e-28 98.6 0.0 3.8e-28 97.8 0.0 1.5 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.10 KLO09017.1 - 1.2e-14 53.5 7.2 2.5e-14 52.5 5.0 1.6 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.17 KLO09017.1 - 1.1e-13 50.6 0.0 5.8e-13 48.3 0.0 2.2 2 0 0 2 2 2 1 Gelsolin repeat S1_2 PF13509.1 KLO09017.1 - 0.013 15.4 0.0 0.029 14.2 0.0 1.6 1 0 0 1 1 1 0 S1 domain Helicase_C PF00271.26 KLO09018.1 - 2.2e-16 59.4 0.0 5.8e-16 58.1 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 KLO09018.1 - 1.8e-14 53.5 0.0 2.9e-14 52.8 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.10 KLO09018.1 - 9e-06 25.6 0.0 2.3e-05 24.3 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit SNF2_N PF00176.18 KLO09018.1 - 0.0044 15.8 0.0 0.007 15.1 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain MFS_1 PF07690.11 KLO09022.1 - 1.6e-21 76.4 41.3 2.1e-14 53.0 17.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily SKG6 PF08693.5 KLO09023.1 - 0.00084 18.5 1.1 0.002 17.3 0.8 1.6 1 0 0 1 1 1 1 Transmembrane alpha-helix domain EphA2_TM PF14575.1 KLO09023.1 - 0.04 14.3 0.0 0.072 13.4 0.0 1.4 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Beta-APP PF03494.8 KLO09023.1 - 9.1 5.8 7.7 18 4.8 5.4 1.4 1 0 0 1 1 1 0 Beta-amyloid peptide (beta-APP) Ribophorin_II PF05817.9 KLO09025.1 - 4.7e-27 94.4 1.4 2.2e-26 92.2 0.9 1.7 1 1 0 1 1 1 1 Oligosaccharyltransferase subunit Ribophorin II Glyco_hydro_47 PF01532.15 KLO09026.1 - 1.6e-120 402.8 0.0 1.9e-120 402.6 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 DUF1832 PF08870.6 KLO09026.1 - 0.081 12.6 0.0 0.19 11.4 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1832) Histone PF00125.19 KLO09027.1 - 3.6e-22 78.2 0.2 5.5e-22 77.6 0.2 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 KLO09027.1 - 5.8e-06 26.2 0.1 5.8e-06 26.2 0.1 1.8 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.8 KLO09027.1 - 0.00027 21.1 0.0 0.00043 20.5 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A DUF1018 PF06252.7 KLO09027.1 - 0.048 14.1 0.4 0.064 13.7 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1018) Bt_P21 PF05560.6 KLO09027.1 - 0.061 12.6 0.1 0.078 12.3 0.0 1.2 1 0 0 1 1 1 0 Bacillus thuringiensis P21 molecular chaperone protein RP-C PF03428.8 KLO09027.1 - 0.091 12.2 0.3 0.17 11.3 0.2 1.7 1 1 0 1 1 1 0 Replication protein C N-terminal domain Histone PF00125.19 KLO09028.1 - 3e-22 78.5 0.1 3.8e-22 78.1 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 KLO09028.1 - 1.1e-05 25.4 0.0 1.7e-05 24.7 0.0 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Pkinase PF00069.20 KLO09029.1 - 7.5e-54 182.5 0.0 9.2e-54 182.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KLO09029.1 - 3e-39 134.6 0.0 4.1e-39 134.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KLO09029.1 - 2.6e-11 43.0 0.0 5.6e-10 38.6 0.0 2.1 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 KLO09029.1 - 0.0012 17.9 0.0 0.0018 17.3 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Oxidored_FMN PF00724.15 KLO09030.1 - 7.7e-72 242.1 0.0 1.3e-71 241.4 0.0 1.3 1 1 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family F-box-like PF12937.2 KLO09032.1 - 8.2e-07 28.6 1.9 9e-07 28.5 0.1 2.1 2 0 0 2 2 2 1 F-box-like F-box-like_2 PF13013.1 KLO09032.1 - 0.00062 19.4 0.1 0.0014 18.2 0.1 1.6 1 0 0 1 1 1 1 F-box-like domain F-box PF00646.28 KLO09032.1 - 0.00094 18.7 0.0 0.0028 17.2 0.0 1.9 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 KLO09033.1 - 1.2e-07 31.3 0.1 3.2e-07 29.9 0.1 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KLO09033.1 - 0.0039 16.7 0.1 0.014 14.9 0.1 2.1 1 1 0 1 1 1 1 F-box domain F-box-like_2 PF13013.1 KLO09033.1 - 0.016 14.9 0.0 0.08 12.6 0.0 2.1 2 0 0 2 2 2 0 F-box-like domain B_lectin PF01453.19 KLO09034.1 - 1.5e-08 34.5 0.0 1.8e-08 34.2 0.0 1.2 1 0 0 1 1 1 1 D-mannose binding lectin Aldo_ket_red PF00248.16 KLO09036.1 - 1.8e-62 210.7 0.0 2e-62 210.5 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Acyl-CoA_dh_M PF02770.14 KLO09037.1 - 0.0089 15.5 0.0 0.018 14.5 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_M PF02770.14 KLO09038.1 - 0.0029 17.0 0.0 0.0053 16.2 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Kp4 PF09044.5 KLO09039.1 - 0.11 12.2 0.1 0.16 11.7 0.1 1.2 1 0 0 1 1 1 0 Kp4 Pkinase PF00069.20 KLO09040.1 - 2.4e-31 108.8 0.0 3e-31 108.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KLO09040.1 - 8.5e-30 103.6 0.0 1.2e-29 103.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KLO09040.1 - 0.0037 16.2 0.0 0.012 14.6 0.0 1.7 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 KLO09040.1 - 0.011 15.4 0.0 0.052 13.2 0.0 1.8 2 1 1 3 3 3 0 Phosphotransferase enzyme family Kdo PF06293.9 KLO09040.1 - 0.035 13.1 0.0 0.06 12.3 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.6 KLO09040.1 - 0.069 11.9 0.0 0.1 11.3 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 NmrA PF05368.8 KLO09041.1 - 5.9e-57 192.5 0.0 7.5e-57 192.2 0.0 1.0 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 KLO09041.1 - 5.5e-16 59.0 0.0 7.2e-16 58.7 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 KLO09041.1 - 2e-07 30.0 0.0 3.1e-07 29.3 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 KLO09041.1 - 9.3e-06 25.2 0.0 1.5e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short PF00106.20 KLO09041.1 - 9.3e-05 22.4 0.1 0.00016 21.6 0.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KLO09041.1 - 0.00015 21.4 0.1 0.00022 20.9 0.0 1.2 1 0 0 1 1 1 1 KR domain TrkA_N PF02254.13 KLO09041.1 - 0.061 13.3 0.1 0.11 12.5 0.1 1.4 1 0 0 1 1 1 0 TrkA-N domain Semialdhyde_dh PF01118.19 KLO09041.1 - 0.073 13.3 0.1 0.14 12.4 0.1 1.5 1 1 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain NAD_binding_4 PF07993.7 KLO09041.1 - 0.09 11.6 0.1 0.13 11.1 0.1 1.2 1 0 0 1 1 1 0 Male sterility protein D5_N PF08706.6 KLO09042.1 - 0.046 13.8 0.2 0.064 13.3 0.2 1.2 1 0 0 1 1 1 0 D5 N terminal like TGT PF01702.13 KLO09047.1 - 0.077 12.2 0.1 0.077 12.2 0.0 1.1 1 0 0 1 1 1 0 Queuine tRNA-ribosyltransferase HTH_29 PF13551.1 KLO09048.1 - 2e-10 40.7 0.0 2.4e-10 40.5 0.0 1.1 1 0 0 1 1 1 1 Winged helix-turn helix HTH_32 PF13565.1 KLO09048.1 - 7.4e-08 33.0 0.0 1.1e-07 32.5 0.0 1.3 1 0 0 1 1 1 1 Homeodomain-like domain HTH_23 PF13384.1 KLO09048.1 - 7.3e-06 25.4 1.4 0.0011 18.5 0.0 2.7 3 0 0 3 3 3 1 Homeodomain-like domain HTH_Tnp_Tc3_2 PF01498.13 KLO09048.1 - 7.2e-05 22.7 0.1 0.00048 20.1 0.0 2.0 2 0 0 2 2 2 1 Transposase HTH_33 PF13592.1 KLO09048.1 - 0.00093 18.6 0.0 0.0016 17.9 0.0 1.4 1 0 0 1 1 1 1 Winged helix-turn helix TrmB PF01978.14 KLO09048.1 - 0.0021 17.6 0.0 0.01 15.4 0.0 1.9 2 0 0 2 2 2 1 Sugar-specific transcriptional regulator TrmB HTH_28 PF13518.1 KLO09048.1 - 0.011 15.7 1.2 0.039 13.9 0.1 2.2 2 0 0 2 2 2 0 Helix-turn-helix domain LacI PF00356.16 KLO09048.1 - 0.019 14.5 0.6 0.47 10.1 0.1 2.4 2 1 0 2 2 2 0 Bacterial regulatory proteins, lacI family HTH_Tnp_ISL3 PF13542.1 KLO09048.1 - 0.024 13.8 0.5 1.6 8.0 0.1 2.4 2 0 0 2 2 2 0 Helix-turn-helix domain of transposase family ISL3 HTH_36 PF13730.1 KLO09048.1 - 0.1 12.7 0.1 0.66 10.1 0.0 2.3 2 1 1 3 3 3 0 Helix-turn-helix domain HTH_11 PF08279.7 KLO09048.1 - 0.17 11.5 0.4 10 5.8 0.1 2.5 2 1 0 2 2 2 0 HTH domain AT_hook PF02178.14 KLO09049.1 - 0.035 13.7 6.1 0.23 11.2 4.2 2.6 1 0 0 1 1 1 0 AT hook motif Erp_C PF06780.6 KLO09049.1 - 0.04 13.7 0.5 0.11 12.3 0.0 2.0 2 0 0 2 2 2 0 Erp protein C-terminus SRP-alpha_N PF04086.8 KLO09049.1 - 1.3 8.3 21.0 0.13 11.6 9.3 2.1 2 0 0 2 2 2 0 Signal recognition particle, alpha subunit, N-terminal DUF4147 PF13660.1 KLO09050.1 - 0.04 13.0 0.0 0.48 9.4 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4147) F-box PF00646.28 KLO09052.1 - 0.0045 16.5 0.9 0.015 14.9 0.6 2.0 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 KLO09052.1 - 0.0082 15.8 0.7 0.019 14.6 0.5 1.6 1 0 0 1 1 1 1 F-box-like Pkinase PF00069.20 KLO09054.1 - 6.7e-09 35.2 1.4 4.8e-08 32.4 0.9 2.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KLO09054.1 - 1.2e-08 34.3 0.3 9e-08 31.4 0.2 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.17 KLO09054.1 - 0.095 12.0 0.0 0.29 10.4 0.0 1.8 2 0 0 2 2 2 0 RIO1 family Myb_DNA-bind_3 PF12776.2 KLO09055.1 - 5.7e-09 36.5 0.6 8.8e-07 29.4 0.4 2.1 1 1 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_4 PF13837.1 KLO09055.1 - 0.00017 21.6 0.6 0.00047 20.2 0.4 2.0 1 1 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-binding PF00249.26 KLO09055.1 - 0.12 12.4 0.2 0.27 11.3 0.2 1.6 1 0 0 1 1 1 0 Myb-like DNA-binding domain DDE_Tnp_4 PF13359.1 KLO09057.1 - 5.1e-10 39.1 0.1 6.4e-10 38.8 0.1 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.9 KLO09057.1 - 0.00022 20.6 0.0 0.00028 20.3 0.0 1.1 1 0 0 1 1 1 1 Plant transposon protein DDE_Tnp_1_2 PF13586.1 KLO09057.1 - 0.0023 18.1 0.0 0.0035 17.4 0.0 1.3 1 0 0 1 1 1 1 Transposase DDE domain HTH_23 PF13384.1 KLO09058.1 - 0.027 14.1 0.0 0.053 13.1 0.0 1.5 1 0 0 1 1 1 0 Homeodomain-like domain HTH_Tnp_4 PF13613.1 KLO09058.1 - 0.053 13.0 0.0 0.081 12.4 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix of DDE superfamily endonuclease Pkinase PF00069.20 KLO09059.1 - 2.5e-27 95.6 0.0 2.9e-27 95.4 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KLO09059.1 - 2.5e-26 92.2 0.0 3.1e-26 92.0 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 KLO09059.1 - 0.038 13.7 0.1 0.052 13.2 0.1 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.9 KLO09059.1 - 0.055 12.5 0.0 0.07 12.1 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Mit_KHE1 PF10173.4 KLO09062.1 - 8.8e-52 175.6 0.1 1.1e-51 175.3 0.1 1.1 1 0 0 1 1 1 1 Mitochondrial K+-H+ exchange-related Piwi PF02171.12 KLO09063.1 - 8.9e-74 248.1 0.0 1.2e-73 247.7 0.0 1.2 1 0 0 1 1 1 1 Piwi domain PAZ PF02170.17 KLO09063.1 - 7.3e-08 31.8 0.0 1.3e-07 31.0 0.0 1.3 1 0 0 1 1 1 1 PAZ domain DUF1785 PF08699.5 KLO09063.1 - 0.00075 18.8 0.3 0.0018 17.5 0.2 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1785) PhyH PF05721.8 KLO09065.1 - 4.2e-05 23.6 0.1 0.0024 17.9 0.0 2.4 2 1 0 2 2 2 2 Phytanoyl-CoA dioxygenase (PhyH) Sigma70_ner PF04546.8 KLO09066.1 - 0.0012 18.5 0.8 0.0023 17.6 0.6 1.4 1 0 0 1 1 1 1 Sigma-70, non-essential region CD99L2 PF12301.3 KLO09066.1 - 0.0021 17.7 3.8 0.0021 17.7 2.6 1.9 2 1 0 2 2 2 1 CD99 antigen like protein 2 Adeno_E3_CR2 PF02439.10 KLO09066.1 - 0.16 11.5 0.4 0.26 10.8 0.3 1.3 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 PBP1_TM PF14812.1 KLO09066.1 - 0.26 11.6 5.5 0.7 10.2 3.8 1.7 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal TMEM154 PF15102.1 KLO09066.1 - 0.37 10.5 1.8 0.91 9.2 0.0 2.2 2 0 0 2 2 2 0 TMEM154 protein family E1_dh PF00676.15 KLO09067.1 - 3.2e-86 288.7 0.0 3.9e-86 288.4 0.0 1.1 1 0 0 1 1 1 1 Dehydrogenase E1 component ATP-synt_C PF00137.16 KLO09068.1 - 0.042 13.7 2.0 0.073 12.9 1.4 1.3 1 0 0 1 1 1 0 ATP synthase subunit C DUF3149 PF11346.3 KLO09068.1 - 0.085 12.4 0.5 0.17 11.4 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3149) Peptidase_C48 PF02902.14 KLO09070.1 - 2e-07 30.8 0.1 2.3e-07 30.6 0.1 1.1 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain COesterase PF00135.23 KLO09072.1 - 7.8e-94 315.2 0.0 1e-93 314.9 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family SM-ATX PF14438.1 KLO09072.1 - 0.15 12.0 0.0 0.3 11.0 0.0 1.4 1 0 0 1 1 1 0 Ataxin 2 SM domain HALZ PF02183.13 KLO09073.1 - 0.049 13.3 4.7 0.077 12.7 0.1 3.2 3 0 0 3 3 3 0 Homeobox associated leucine zipper SKN1 PF03935.10 KLO09074.1 - 3e-204 678.8 7.2 3.5e-204 678.6 5.0 1.0 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) Tom37_C PF11801.3 KLO09075.1 - 0.47 10.3 2.4 0.32 10.8 0.2 1.7 1 1 1 2 2 2 0 Tom37 C-terminal domain YqaJ PF09588.5 KLO09080.1 - 0.072 13.0 0.9 0.081 12.8 0.6 1.1 1 0 0 1 1 1 0 YqaJ-like viral recombinase domain Phasin PF05597.6 KLO09081.1 - 0.051 13.3 3.4 0.25 11.1 1.0 2.9 3 0 0 3 3 3 0 Poly(hydroxyalcanoate) granule associated protein (phasin) DUF972 PF06156.8 KLO09081.1 - 0.11 12.8 12.8 2.8 8.3 0.0 4.1 3 1 2 5 5 5 0 Protein of unknown function (DUF972) TMPIT PF07851.8 KLO09081.1 - 0.91 8.5 9.7 0.41 9.6 2.8 2.3 2 0 0 2 2 2 0 TMPIT-like protein Fib_alpha PF08702.5 KLO09081.1 - 7.8 6.6 13.3 30 4.7 6.2 3.2 3 1 0 3 3 3 0 Fibrinogen alpha/beta chain family Atg14 PF10186.4 KLO09082.1 - 0.048 12.6 3.0 0.061 12.2 1.7 1.4 1 1 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 CENP-Q PF13094.1 KLO09082.1 - 0.45 10.5 12.3 9.8 6.1 8.6 2.6 1 1 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit HALZ PF02183.13 KLO09082.1 - 0.76 9.5 4.3 2.6 7.8 0.4 2.7 2 0 0 2 2 2 0 Homeobox associated leucine zipper DUF1640 PF07798.6 KLO09082.1 - 2.3 8.2 5.9 10 6.1 4.1 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF1640) DUF972 PF06156.8 KLO09082.1 - 2.9 8.2 6.3 20 5.5 0.5 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF972) Spc24 PF08286.6 KLO09082.1 - 3.1 7.5 6.0 2.9 7.6 0.5 2.4 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 Ax_dynein_light PF10211.4 KLO09082.1 - 3.3 7.5 11.1 1.1 9.0 0.7 2.2 1 1 1 2 2 2 0 Axonemal dynein light chain Mod_r PF07200.8 KLO09083.1 - 0.00098 19.0 4.2 0.00098 19.0 2.9 2.7 3 0 0 3 3 3 1 Modifier of rudimentary (Mod(r)) protein Reo_sigmaC PF04582.7 KLO09083.1 - 0.022 13.9 2.5 0.043 12.9 1.7 1.6 1 0 0 1 1 1 0 Reovirus sigma C capsid protein Spc7 PF08317.6 KLO09083.1 - 0.036 12.7 14.1 0.096 11.3 4.2 2.8 1 1 2 3 3 3 0 Spc7 kinetochore protein HALZ PF02183.13 KLO09083.1 - 0.5 10.1 6.9 15 5.4 0.0 3.1 2 1 0 2 2 2 0 Homeobox associated leucine zipper DUF4446 PF14584.1 KLO09083.1 - 0.78 9.5 4.7 2.4 7.9 0.1 2.5 1 1 2 3 3 3 0 Protein of unknown function (DUF4446) FUSC PF04632.7 KLO09083.1 - 0.78 8.0 11.9 1 7.6 8.2 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF972 PF06156.8 KLO09083.1 - 1.4 9.3 7.4 21 5.5 0.0 2.9 1 1 0 2 2 2 0 Protein of unknown function (DUF972) TPR_MLP1_2 PF07926.7 KLO09083.1 - 2.7 7.7 15.4 0.97 9.1 3.1 3.1 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein Atg14 PF10186.4 KLO09083.1 - 8.2 5.2 12.9 2.9 6.7 5.3 2.0 1 1 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 MscS_porin PF12795.2 KLO09084.1 - 1.3e-05 24.6 15.6 1.3e-05 24.6 10.8 4.8 1 1 4 5 5 5 1 Mechanosensitive ion channel porin domain TPR_MLP1_2 PF07926.7 KLO09084.1 - 2e-05 24.3 73.6 0.018 14.7 8.7 6.4 3 1 2 6 6 6 4 TPR/MLP1/MLP2-like protein Filament PF00038.16 KLO09084.1 - 0.00013 21.6 41.5 0.00013 21.6 28.8 3.0 2 1 1 3 3 3 1 Intermediate filament protein ATG16 PF08614.6 KLO09084.1 - 0.0064 16.3 9.3 0.0064 16.3 6.5 5.8 3 1 3 6 6 6 2 Autophagy protein 16 (ATG16) Tup_N PF08581.5 KLO09084.1 - 0.019 15.1 34.9 0.055 13.6 0.9 5.9 5 1 1 6 6 6 0 Tup N-terminal IncA PF04156.9 KLO09084.1 - 0.13 11.8 73.2 0.047 13.2 13.8 5.5 2 1 3 5 5 5 0 IncA protein GAS PF13851.1 KLO09084.1 - 0.23 10.6 62.3 0.35 10.0 10.0 5.6 2 1 3 5 5 5 0 Growth-arrest specific micro-tubule binding Tropomyosin_1 PF12718.2 KLO09084.1 - 0.8 9.5 85.4 0.092 12.5 9.8 4.8 2 1 3 5 5 5 0 Tropomyosin like Reo_sigmaC PF04582.7 KLO09084.1 - 1.8 7.6 34.8 0.19 10.8 3.4 4.4 2 1 3 5 5 5 0 Reovirus sigma C capsid protein DUF2730 PF10805.3 KLO09084.1 - 4.6 7.0 28.9 1 9.0 1.1 5.3 3 2 2 5 5 5 0 Protein of unknown function (DUF2730) SecD-TM1 PF13721.1 KLO09084.1 - 7.4 6.8 23.2 0.46 10.7 2.4 4.0 3 1 1 4 4 4 0 SecD export protein N-terminal TM region Hemerythrin PF01814.18 KLO09084.1 - 8 6.6 30.6 74 3.5 0.4 4.9 3 1 1 4 4 4 0 Hemerythrin HHE cation binding domain LSM PF01423.17 KLO09085.1 - 1.7e-18 65.9 1.4 2.2e-18 65.5 1.0 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 KLO09085.1 - 0.012 15.5 0.1 0.015 15.1 0.1 1.2 1 0 0 1 1 1 0 Ataxin 2 SM domain BPL_C PF02237.12 KLO09085.1 - 0.034 13.8 1.2 0.048 13.3 0.2 1.7 2 0 0 2 2 2 0 Biotin protein ligase C terminal domain Gemin7 PF11095.3 KLO09085.1 - 0.069 12.8 0.1 0.092 12.4 0.0 1.2 1 0 0 1 1 1 0 Gem-associated protein 7 (Gemin7) CDC45 PF02724.9 KLO09087.1 - 0.056 11.4 5.6 0.92 7.4 2.0 2.1 2 0 0 2 2 2 0 CDC45-like protein PSD5 PF07637.6 KLO09087.1 - 0.16 12.0 2.2 3.2 7.8 0.1 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF1595) Vir_act_alpha_C PF10400.4 KLO09087.1 - 7.4 7.0 7.9 6.5 7.2 0.2 2.9 3 0 0 3 3 3 0 Virulence activator alpha C-term ThiF PF00899.16 KLO09088.1 - 7.8e-16 58.1 0.0 1.2e-15 57.4 0.0 1.3 1 0 0 1 1 1 1 ThiF family MoeZ_MoeB PF05237.8 KLO09088.1 - 0.036 13.6 0.0 0.19 11.3 0.0 2.1 2 0 0 2 2 2 0 MoeZ/MoeB domain Fungal_trans PF04082.13 KLO09090.1 - 6.1e-22 77.7 0.0 1e-21 76.9 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KLO09090.1 - 6.9e-07 29.0 10.0 1.3e-06 28.2 7.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PPR_2 PF13041.1 KLO09092.1 - 0.011 15.7 0.0 0.026 14.4 0.0 1.7 1 0 0 1 1 1 0 PPR repeat family zf-C2H2_4 PF13894.1 KLO09094.1 - 2.8e-09 36.6 8.1 5.8e-05 23.1 1.7 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.21 KLO09094.1 - 3.4e-09 36.4 11.5 0.00014 21.9 2.4 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-BED PF02892.10 KLO09094.1 - 8.4e-06 25.4 5.5 0.00019 21.1 1.4 2.4 1 1 1 2 2 2 1 BED zinc finger zf-H2C2_2 PF13465.1 KLO09094.1 - 0.0006 19.9 10.3 0.019 15.2 0.4 3.4 3 1 0 3 3 3 2 Zinc-finger double domain zf-Di19 PF05605.7 KLO09094.1 - 0.0065 16.5 7.0 0.18 11.9 0.2 3.2 3 0 0 3 3 3 1 Drought induced 19 protein (Di19), zinc-binding Tmemb_55A PF09788.4 KLO09094.1 - 0.051 12.6 0.2 0.051 12.6 0.1 1.6 1 1 1 2 2 2 0 Transmembrane protein 55A Elf1 PF05129.8 KLO09094.1 - 0.065 12.9 0.1 0.12 12.0 0.1 1.4 1 0 0 1 1 1 0 Transcription elongation factor Elf1 like zf-met PF12874.2 KLO09094.1 - 0.091 12.9 2.3 0.25 11.6 0.2 2.5 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 KLO09094.1 - 0.14 12.3 0.3 0.14 12.3 0.2 2.8 3 0 0 3 3 2 0 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.2 KLO09094.1 - 0.43 10.7 9.3 0.47 10.5 0.4 2.8 2 1 1 3 3 3 0 C2H2 type zinc-finger (2 copies) zf-RING_3 PF14369.1 KLO09094.1 - 0.53 10.3 3.9 0.91 9.5 0.9 2.2 2 0 0 2 2 2 0 zinc-finger zf-C2HC_2 PF13913.1 KLO09094.1 - 2.1 8.1 8.5 0.44 10.2 1.7 2.3 2 0 0 2 2 2 0 zinc-finger of a C2HC-type PAT1 PF09770.4 KLO09094.1 - 2.4 6.2 22.4 2.7 6.1 15.6 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Cytadhesin_P30 PF07271.6 KLO09095.1 - 0.026 13.8 0.1 0.035 13.3 0.0 1.2 1 0 0 1 1 1 0 Cytadhesin P30/P32 Metallophos PF00149.23 KLO09096.1 - 1.1e-38 132.6 0.4 1.5e-38 132.2 0.3 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 KLO09096.1 - 0.005 16.6 0.0 0.0065 16.3 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain SET PF00856.23 KLO09098.1 - 1.2e-11 45.2 0.0 2.8e-11 43.9 0.0 1.6 1 1 0 1 1 1 1 SET domain Rubis-subs-bind PF09273.6 KLO09098.1 - 1.3e-10 41.2 0.0 3.8e-10 39.7 0.0 1.8 1 0 0 1 1 1 1 Rubisco LSMT substrate-binding CENP-B_dimeris PF09026.5 KLO09098.1 - 0.14 12.4 8.1 0.33 11.2 5.6 1.6 1 0 0 1 1 1 0 Centromere protein B dimerisation domain BUD22 PF09073.5 KLO09098.1 - 0.96 8.4 10.1 1.6 7.7 7.0 1.3 1 0 0 1 1 1 0 BUD22 F-box-like PF12937.2 KLO09099.1 - 1e-05 25.1 0.3 7.8e-05 22.3 0.2 2.5 2 0 0 2 2 2 1 F-box-like F-box-like PF12937.2 KLO09100.1 - 9.1e-06 25.3 0.4 2.3e-05 24.0 0.3 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KLO09100.1 - 0.0066 16.0 0.6 0.021 14.4 0.4 1.9 1 1 0 1 1 1 1 F-box domain F-box-like_2 PF13013.1 KLO09100.1 - 0.12 12.0 1.4 0.61 9.8 0.2 2.4 1 1 1 2 2 2 0 F-box-like domain DUF3603 PF12227.3 KLO09100.1 - 0.17 10.9 0.0 0.32 10.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3603) CBFB_NFYA PF02045.10 KLO09101.1 - 7.2e-30 103.3 7.2 8.2e-30 103.1 5.0 1.0 1 0 0 1 1 1 1 CCAAT-binding transcription factor (CBF-B/NF-YA) subunit B peroxidase PF00141.18 KLO09102.1 - 2.3e-30 105.8 0.0 3.6e-30 105.1 0.0 1.4 1 0 0 1 1 1 1 Peroxidase DUF3415 PF11895.3 KLO09102.1 - 1.2e-23 82.7 3.2 1.3e-23 82.6 1.2 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF3415) DUF627 PF04781.7 KLO09102.1 - 0.052 13.1 0.1 0.086 12.4 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF627) DltD_C PF04914.7 KLO09103.1 - 0.048 13.5 0.0 0.054 13.3 0.0 1.1 1 0 0 1 1 1 0 DltD C-terminal region Rota_VP2 PF05087.7 KLO09103.1 - 0.082 10.8 0.0 0.09 10.6 0.0 1.0 1 0 0 1 1 1 0 Rotavirus VP2 protein SPC22 PF04573.7 KLO09104.1 - 6.9e-40 136.1 0.0 7.7e-40 135.9 0.0 1.0 1 0 0 1 1 1 1 Signal peptidase subunit Tweety PF04906.8 KLO09105.1 - 0.36 9.1 0.1 0.57 8.5 0.0 1.2 1 0 0 1 1 1 0 Tweety TFIIIC_sub6 PF10419.4 KLO09106.1 - 4.5e-07 29.2 0.0 6.5e-07 28.7 0.0 1.2 1 0 0 1 1 1 1 TFIIIC subunit MFS_1 PF07690.11 KLO09107.1 - 3.4e-22 78.6 39.4 5.3e-22 77.9 27.3 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily p450 PF00067.17 KLO09108.1 - 5.5e-77 259.2 0.0 6.2e-77 259.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 KLO09109.1 - 3.3e-69 233.5 0.0 3.8e-69 233.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 CAP_GLY PF01302.20 KLO09110.1 - 6.3e-20 70.6 0.7 1.1e-19 69.9 0.5 1.4 1 0 0 1 1 1 1 CAP-Gly domain GAS PF13851.1 KLO09110.1 - 0.00069 18.8 8.8 0.00069 18.8 6.1 6.3 2 2 3 6 6 6 2 Growth-arrest specific micro-tubule binding TMF_DNA_bd PF12329.3 KLO09110.1 - 0.0013 18.5 9.4 0.0013 18.5 6.5 9.8 6 4 3 10 10 10 4 TATA element modulatory factor 1 DNA binding Reo_sigmaC PF04582.7 KLO09110.1 - 0.0042 16.3 36.1 0.0049 16.0 2.8 5.0 1 1 4 6 6 6 3 Reovirus sigma C capsid protein Filament PF00038.16 KLO09110.1 - 0.0052 16.3 92.1 0.13 11.7 2.2 5.0 2 1 2 4 4 4 4 Intermediate filament protein ThiS PF02597.15 KLO09110.1 - 0.0086 16.4 0.1 0.36 11.2 0.1 3.9 1 0 0 1 1 1 1 ThiS family NAAA-beta PF15508.1 KLO09110.1 - 0.03 14.6 2.5 1.7 9.0 0.1 2.9 2 0 0 2 2 2 0 beta subunit of N-acylethanolamine-hydrolyzing acid amidase zf-CCHC_4 PF14392.1 KLO09110.1 - 7.5 6.3 7.6 1.2 8.8 0.9 2.3 2 0 0 2 2 2 0 Zinc knuckle ERG4_ERG24 PF01222.12 KLO09111.1 - 1.4e-140 468.6 7.2 1.6e-140 468.5 5.0 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF1295 PF06966.7 KLO09111.1 - 2.8e-07 30.0 0.1 6.3e-07 28.9 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) PEMT PF04191.8 KLO09111.1 - 3.9e-05 23.6 0.3 0.00027 20.9 0.0 2.6 2 0 0 2 2 2 1 Phospholipid methyltransferase DUF2919 PF11143.3 KLO09111.1 - 0.0046 16.7 0.3 0.014 15.1 0.2 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF2919) ICMT PF04140.9 KLO09111.1 - 0.016 15.3 0.0 0.067 13.3 0.0 2.1 1 0 0 1 1 1 0 Isoprenylcysteine carboxyl methyltransferase (ICMT) family Spc7_N PF15402.1 KLO09113.1 - 2.2 6.1 13.6 2.5 6.0 9.4 1.0 1 0 0 1 1 1 0 N-terminus of kinetochore NMS complex subunit Spc7 Zip PF02535.17 KLO09113.1 - 2.9 6.8 6.7 3 6.7 4.6 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter CEP170_C PF15308.1 KLO09113.1 - 9.4 4.3 16.5 9.8 4.2 11.4 1.0 1 0 0 1 1 1 0 CEP170 C-terminus TPR_2 PF07719.12 KLO09114.1 - 5e-31 104.0 17.9 0.00025 20.7 0.1 13.3 13 0 0 13 13 13 8 Tetratricopeptide repeat TPR_11 PF13414.1 KLO09114.1 - 7e-31 105.6 33.6 1.2e-08 34.4 0.0 9.8 7 3 1 9 9 9 7 TPR repeat TPR_1 PF00515.23 KLO09114.1 - 1.2e-30 103.8 16.6 0.00011 21.6 0.0 12.1 14 0 0 14 14 14 8 Tetratricopeptide repeat TPR_19 PF14559.1 KLO09114.1 - 2e-28 98.5 21.2 4.7e-05 23.6 0.5 9.9 8 2 2 10 10 9 7 Tetratricopeptide repeat TPR_14 PF13428.1 KLO09114.1 - 8.7e-24 81.8 25.1 1.9e-05 24.8 0.2 13.2 8 4 5 13 13 12 4 Tetratricopeptide repeat TPR_12 PF13424.1 KLO09114.1 - 1.6e-21 76.0 30.9 8.3e-08 32.0 0.3 9.7 7 3 3 10 10 10 7 Tetratricopeptide repeat TPR_8 PF13181.1 KLO09114.1 - 2.6e-20 70.6 15.3 0.0012 18.4 0.0 11.8 13 0 0 13 13 13 4 Tetratricopeptide repeat TPR_16 PF13432.1 KLO09114.1 - 1.1e-15 57.8 51.3 0.00029 21.4 0.7 11.7 12 0 0 12 12 11 4 Tetratricopeptide repeat TPR_6 PF13174.1 KLO09114.1 - 9.6e-15 53.9 21.1 8.1e-06 25.9 0.1 11.3 13 0 0 13 13 10 3 Tetratricopeptide repeat TPR_17 PF13431.1 KLO09114.1 - 1.8e-14 52.6 14.8 1.3 9.3 0.0 12.5 12 0 0 12 12 12 3 Tetratricopeptide repeat TPR_7 PF13176.1 KLO09114.1 - 2.5e-13 48.7 10.6 0.012 15.3 0.1 10.0 11 0 0 11 11 11 3 Tetratricopeptide repeat TPR_10 PF13374.1 KLO09114.1 - 0.0034 17.2 18.1 6.2 6.8 0.0 8.0 8 0 0 8 8 7 2 Tetratricopeptide repeat ChAPs PF09295.5 KLO09114.1 - 0.0077 15.0 0.2 0.34 9.6 0.0 2.7 2 0 0 2 2 2 1 ChAPs (Chs5p-Arf1p-binding proteins) TPR_4 PF07721.9 KLO09114.1 - 0.22 12.0 7.9 3.6 8.3 0.0 5.5 5 0 0 5 5 5 0 Tetratricopeptide repeat Hydrophobin PF01185.13 KLO09115.1 - 1.1e-21 77.0 11.7 1.6e-21 76.5 8.1 1.2 1 0 0 1 1 1 1 Fungal hydrophobin DUF1427 PF07235.6 KLO09115.1 - 0.078 13.0 0.7 0.14 12.3 0.3 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1427) gpUL132 PF11359.3 KLO09115.1 - 1.5 8.1 7.1 1.8 7.8 4.9 1.1 1 0 0 1 1 1 0 Glycoprotein UL132 Med3 PF11593.3 KLO09115.1 - 8 5.5 7.3 8.8 5.4 5.1 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal LysM PF01476.15 KLO09116.1 - 0.00042 20.1 0.0 0.00071 19.4 0.0 1.4 1 0 0 1 1 1 1 LysM domain CLASP_N PF12348.3 KLO09117.1 - 4.3e-26 91.6 0.1 5e-26 91.4 0.1 1.0 1 0 0 1 1 1 1 CLASP N terminal DUF1320 PF07030.7 KLO09117.1 - 0.054 13.2 0.1 0.23 11.2 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1320) Pkinase PF00069.20 KLO09119.1 - 2e-63 213.9 0.0 2.3e-63 213.7 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KLO09119.1 - 2.4e-44 151.3 0.0 3e-44 151.0 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KLO09119.1 - 1.8e-05 23.8 0.0 2.9e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 KLO09119.1 - 0.0038 16.9 0.0 1.9 8.1 0.0 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.9 KLO09119.1 - 0.0072 15.4 0.0 0.012 14.6 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APS_kinase PF01583.15 KLO09120.1 - 8.6e-70 233.4 0.0 1e-69 233.1 0.0 1.0 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_33 PF13671.1 KLO09120.1 - 2e-06 27.7 0.0 3.3e-06 27.0 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 KLO09120.1 - 4.2e-06 27.5 0.1 7.5e-06 26.7 0.1 1.4 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 KLO09120.1 - 8e-05 22.9 0.1 0.00027 21.2 0.0 2.1 2 1 0 2 2 2 1 AAA domain AAA_29 PF13555.1 KLO09120.1 - 0.0049 16.3 0.0 0.008 15.6 0.0 1.3 1 0 0 1 1 1 1 P-loop containing region of AAA domain KTI12 PF08433.5 KLO09120.1 - 0.012 14.8 0.0 0.014 14.6 0.0 1.2 1 0 0 1 1 1 0 Chromatin associated protein KTI12 CPT PF07931.7 KLO09120.1 - 0.094 12.3 0.0 0.59 9.7 0.0 2.0 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein CybS PF05328.7 KLO09121.1 - 5.1e-43 145.8 0.0 6.3e-43 145.5 0.0 1.1 1 0 0 1 1 1 1 CybS Hemerythrin PF01814.18 KLO09122.1 - 1.5e-13 51.0 0.8 2.3e-13 50.4 0.6 1.2 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain HAD_2 PF13419.1 KLO09123.1 - 1.4e-24 87.2 0.0 1.8e-24 86.9 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 KLO09123.1 - 2e-05 24.2 0.0 3.6e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 HAD-hyrolase-like DUF2608 PF11019.3 KLO09123.1 - 0.036 13.0 0.0 0.079 11.9 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2608) NIF PF03031.13 KLO09123.1 - 0.037 13.6 0.0 0.08 12.5 0.0 1.6 2 0 0 2 2 2 0 NLI interacting factor-like phosphatase HAD_2 PF13419.1 KLO09124.1 - 2.2e-28 99.6 0.0 3.9e-28 98.8 0.0 1.4 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Prenyltrans_2 PF13249.1 KLO09124.1 - 0.00046 20.5 0.0 0.91 9.9 0.0 2.5 2 0 0 2 2 2 2 Prenyltransferase-like Hydrolase_like PF13242.1 KLO09124.1 - 0.00053 19.6 0.0 0.0013 18.3 0.0 1.6 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.21 KLO09124.1 - 0.13 12.6 0.0 0.58 10.5 0.0 1.9 2 1 1 3 3 3 0 haloacid dehalogenase-like hydrolase GST_N_3 PF13417.1 KLO09127.1 - 2.4e-09 37.2 0.0 4.5e-09 36.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 KLO09127.1 - 5e-08 32.8 0.0 8.9e-08 32.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 KLO09127.1 - 2.7e-07 30.6 0.0 5.3e-07 29.7 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 KLO09127.1 - 4.4e-07 29.6 0.1 7.1e-07 29.0 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 KLO09127.1 - 7.2e-07 29.1 0.0 1.3e-06 28.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 KLO09127.1 - 0.027 14.9 0.0 0.038 14.4 0.0 1.3 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain F-box-like PF12937.2 KLO09128.1 - 4.5e-07 29.4 0.2 3e-06 26.8 0.0 2.6 2 0 0 2 2 2 1 F-box-like F-box-like PF12937.2 KLO09129.1 - 1.4e-06 27.9 1.3 2.2e-05 24.0 0.1 3.1 3 0 0 3 3 3 1 F-box-like F-box-like_2 PF13013.1 KLO09129.1 - 0.14 11.9 0.6 0.26 11.0 0.1 1.7 2 0 0 2 2 2 0 F-box-like domain F-box-like PF12937.2 KLO09130.1 - 8.3e-08 31.8 1.7 1.9e-07 30.6 0.5 2.1 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 KLO09130.1 - 0.0027 17.3 0.1 0.017 14.7 0.0 2.4 1 1 0 1 1 1 1 F-box domain F-box-like PF12937.2 KLO09131.1 - 2.6e-07 30.2 7.8 3e-07 30.0 0.5 3.0 3 0 0 3 3 3 1 F-box-like EMI PF07546.8 KLO09131.1 - 0.063 13.7 0.0 0.53 10.7 0.0 2.3 2 0 0 2 2 2 0 EMI domain Cytokin_check_N PF10407.4 KLO09131.1 - 0.088 12.4 0.0 0.19 11.3 0.0 1.5 1 0 0 1 1 1 0 Cdc14 phosphatase binding protein N-terminus LRR_4 PF12799.2 KLO09131.1 - 2.6 7.7 5.0 11 5.7 0.0 4.1 4 1 0 4 4 4 0 Leucine Rich repeats (2 copies) Ferrochelatase PF00762.14 KLO09133.1 - 7.2e-98 327.4 0.0 8.1e-98 327.2 0.0 1.0 1 0 0 1 1 1 1 Ferrochelatase DUF389 PF04087.9 KLO09134.1 - 0.004 17.1 2.1 0.007 16.3 1.4 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF389) DUF1469 PF07332.6 KLO09134.1 - 0.18 11.5 5.3 0.66 9.7 0.0 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF1469) DDE_Tnp_4 PF13359.1 KLO09136.1 - 7.5e-23 80.8 0.0 1.3e-22 80.0 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease Myb_DNA-bind_4 PF13837.1 KLO09137.1 - 0.016 15.3 0.5 0.016 15.3 0.3 2.2 2 0 0 2 2 2 0 Myb/SANT-like DNA-binding domain DUF2408 PF10303.4 KLO09137.1 - 1.7 8.7 7.0 2 8.5 0.7 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2408) F-box-like PF12937.2 KLO09141.1 - 1.8e-08 33.9 0.0 6.2e-08 32.2 0.0 2.0 2 0 0 2 2 2 1 F-box-like Con-6 PF10346.4 KLO09142.1 - 2.1e-07 30.2 0.1 4.2e-07 29.2 0.1 1.5 1 0 0 1 1 1 1 Conidiation protein 6 DUF4106 PF13388.1 KLO09142.1 - 0.029 13.3 1.1 0.034 13.0 0.7 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4106) HWE_HK PF07536.9 KLO09142.1 - 0.083 13.3 2.1 0.19 12.1 0.5 2.0 2 0 0 2 2 2 0 HWE histidine kinase GMC_oxred_N PF00732.14 KLO09144.1 - 1.8e-63 214.4 0.0 2.3e-63 214.0 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 KLO09144.1 - 1.2e-34 119.7 0.0 2.2e-34 118.8 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 KLO09144.1 - 6.2e-06 25.3 0.6 7.1e-05 21.8 0.0 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 KLO09144.1 - 0.00017 20.6 0.0 0.00032 19.7 0.0 1.4 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_3 PF13738.1 KLO09144.1 - 0.00019 21.5 0.0 0.37 10.8 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KLO09144.1 - 0.00027 20.9 0.1 0.00083 19.3 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 KLO09144.1 - 0.00095 18.1 0.8 0.002 17.0 0.1 1.8 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.9 KLO09144.1 - 0.0013 18.6 0.0 0.0042 16.9 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.13 KLO09144.1 - 0.0021 18.0 0.1 0.044 13.7 0.0 2.4 2 0 0 2 2 2 1 TrkA-N domain Thi4 PF01946.12 KLO09144.1 - 0.0028 16.7 0.1 0.006 15.7 0.1 1.5 1 0 0 1 1 1 1 Thi4 family HI0933_like PF03486.9 KLO09144.1 - 0.046 12.1 0.4 0.16 10.4 0.0 1.8 2 0 0 2 2 2 0 HI0933-like protein NAD_binding_9 PF13454.1 KLO09144.1 - 0.051 13.3 0.1 0.17 11.6 0.0 1.9 2 0 0 2 2 2 0 FAD-NAD(P)-binding Trp_halogenase PF04820.9 KLO09144.1 - 0.094 11.3 0.0 0.15 10.6 0.0 1.2 1 0 0 1 1 1 0 Tryptophan halogenase ADH_N PF08240.7 KLO09145.1 - 6.9e-26 90.1 0.1 1.1e-25 89.4 0.1 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KLO09145.1 - 2e-08 33.8 0.0 3.7e-07 29.7 0.0 2.5 2 0 0 2 2 2 1 Zinc-binding dehydrogenase DUF1355 PF07090.6 KLO09145.1 - 0.037 13.3 0.0 0.068 12.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1355) NAD_binding_9 PF13454.1 KLO09145.1 - 0.062 13.0 0.0 0.092 12.5 0.0 1.2 1 0 0 1 1 1 0 FAD-NAD(P)-binding NADH_4Fe-4S PF10589.4 KLO09145.1 - 0.29 10.3 5.0 0.63 9.2 3.5 1.5 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region Archease PF01951.11 KLO09146.1 - 0.089 12.7 0.5 0.3 11.0 0.3 2.0 1 1 0 1 1 1 0 Archease protein family (MTH1598/TM1083) ARGLU PF15346.1 KLO09146.1 - 1 9.1 27.0 0.25 11.1 16.4 1.6 2 0 0 2 2 2 0 Arginine and glutamate-rich 1 DUF1423 PF07227.6 KLO09146.1 - 1.1 7.8 12.0 1.7 7.2 8.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1423) SBP_bac_7 PF03480.8 KLO09146.1 - 6.3 5.8 7.7 0.81 8.7 2.6 1.4 2 0 0 2 2 2 0 Bacterial extracellular solute-binding protein, family 7 Fe-ADH PF00465.14 KLO09147.1 - 1.4e-66 224.6 0.0 1.8e-66 224.2 0.0 1.0 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.1 KLO09147.1 - 1.2e-15 57.5 0.0 1.9e-15 56.8 0.0 1.3 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase FUSC_2 PF13515.1 KLO09148.1 - 5.4e-21 74.8 7.1 5.4e-21 74.8 4.9 2.6 2 0 0 2 2 2 1 Fusaric acid resistance protein-like FUSC PF04632.7 KLO09148.1 - 1.4e-14 53.5 21.6 7.7e-14 51.0 3.0 3.3 3 0 0 3 3 3 2 Fusaric acid resistance protein family ALMT PF11744.3 KLO09148.1 - 2.6e-11 42.8 11.2 1e-08 34.2 3.8 2.4 2 0 0 2 2 2 2 Aluminium activated malate transporter DUF2421 PF10334.4 KLO09148.1 - 1.6e-09 37.6 1.3 1.6e-08 34.4 0.3 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF2421) DUF939 PF06081.6 KLO09148.1 - 0.00013 21.8 3.8 0.00013 21.8 2.6 3.3 3 2 0 3 3 3 1 Bacterial protein of unknown function (DUF939) DUF3584 PF12128.3 KLO09148.1 - 0.087 10.1 1.6 0.14 9.4 1.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) HSP70 PF00012.15 KLO09149.1 - 0.00044 18.3 0.0 0.00074 17.5 0.0 1.2 1 0 0 1 1 1 1 Hsp70 protein Abhydrolase_3 PF07859.8 KLO09150.1 - 4.7e-28 98.1 0.1 9.7e-28 97.1 0.0 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold DUF2424 PF10340.4 KLO09150.1 - 1.3e-12 47.1 0.0 4.2e-11 42.1 0.0 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF2424) Abhydrolase_5 PF12695.2 KLO09150.1 - 0.005 16.6 0.0 0.0066 16.2 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family K167R PF08065.7 KLO09151.1 - 0.57 10.3 7.5 6.4 6.9 4.6 2.1 2 0 0 2 2 2 0 K167R (NUC007) repeat DUF2462 PF09495.5 KLO09151.1 - 5.3 7.8 6.7 3.7 8.3 3.0 2.0 2 1 0 2 2 2 0 Protein of unknown function (DUF2462) AAA_18 PF13238.1 KLO09152.1 - 1.1e-07 32.2 0.3 6.8e-07 29.6 0.2 1.9 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 KLO09152.1 - 4.1e-06 27.6 0.0 8.6e-06 26.5 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_28 PF13521.1 KLO09152.1 - 0.014 15.3 0.0 0.029 14.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.1 KLO09152.1 - 0.05 13.4 0.1 0.51 10.2 0.0 2.3 2 1 0 2 2 2 0 AAA domain PRK PF00485.13 KLO09152.1 - 0.073 12.6 0.1 0.26 10.8 0.0 1.9 1 1 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family T2SE PF00437.15 KLO09152.1 - 0.089 11.6 0.1 0.13 11.1 0.1 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein Zeta_toxin PF06414.7 KLO09152.1 - 0.11 11.6 0.1 0.23 10.5 0.0 1.6 2 0 0 2 2 2 0 Zeta toxin Peptidase_M28 PF04389.12 KLO09153.1 - 5.7e-27 94.5 0.0 8.7e-27 93.9 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.23 KLO09153.1 - 0.00019 21.0 0.0 0.00031 20.2 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Peptidase_M42 PF05343.9 KLO09153.1 - 0.0039 16.0 0.0 0.01 14.6 0.0 1.5 1 1 1 2 2 2 1 M42 glutamyl aminopeptidase Peptidase_M28 PF04389.12 KLO09154.1 - 3.2e-27 95.4 0.0 5.9e-27 94.5 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M28 DUF3272 PF11676.3 KLO09154.1 - 3.6 7.6 8.2 22 5.1 3.7 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3272) BTB PF00651.26 KLO09155.1 - 1.9e-05 24.6 0.0 3.8e-05 23.6 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain BTB PF00651.26 KLO09156.1 - 9e-05 22.4 0.1 0.00023 21.0 0.1 1.7 1 1 0 1 1 1 1 BTB/POZ domain NCKAP5 PF15246.1 KLO09157.1 - 0.11 11.8 0.0 0.16 11.3 0.0 1.2 1 0 0 1 1 1 0 Nck-associated protein 5, Peripheral clock protein PilJ PF13675.1 KLO09160.1 - 0.029 14.7 0.1 0.13 12.5 0.0 1.9 2 0 0 2 2 2 0 Type IV pili methyl-accepting chemotaxis transducer N-term Pmp3 PF01679.12 KLO09161.1 - 1.7e-12 46.8 2.4 3.2e-12 45.9 1.7 1.4 1 0 0 1 1 1 1 Proteolipid membrane potential modulator DUF4138 PF13595.1 KLO09161.1 - 0.07 12.0 0.0 0.088 11.7 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4138) MgtE PF01769.11 KLO09163.1 - 0.076 13.3 6.8 0.27 11.5 0.8 2.4 2 0 0 2 2 2 0 Divalent cation transporter Ribosomal_L14 PF00238.14 KLO09165.1 - 2.6e-30 104.6 0.0 3e-30 104.4 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e zf-MYND PF01753.13 KLO09168.1 - 4.7e-11 42.3 11.4 1.5e-10 40.7 7.9 1.9 1 0 0 1 1 1 1 MYND finger zf-Mss51 PF13824.1 KLO09168.1 - 0.023 14.5 6.4 0.023 14.5 4.4 2.0 2 0 0 2 2 2 0 Zinc-finger of mitochondrial splicing suppressor 51 zf-MYND PF01753.13 KLO09171.1 - 4e-10 39.3 10.6 4e-10 39.3 7.3 1.6 2 0 0 2 2 2 1 MYND finger zf-RING_2 PF13639.1 KLO09171.1 - 0.14 12.0 6.3 0.28 11.0 4.4 1.5 1 0 0 1 1 1 0 Ring finger domain HET PF06985.6 KLO09173.1 - 0.00031 20.8 0.0 0.41 10.8 0.0 2.9 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) zf-MYND PF01753.13 KLO09175.1 - 6.3e-08 32.3 13.9 6.3e-08 32.3 9.6 1.6 2 0 0 2 2 2 1 MYND finger Ecl1 PF12855.2 KLO09175.1 - 6.7 6.0 12.9 1.3 8.3 6.0 2.0 2 0 0 2 2 2 0 Life-span regulatory factor zf-MYND PF01753.13 KLO09176.1 - 0.018 14.8 2.7 0.018 14.8 1.8 2.3 2 0 0 2 2 2 0 MYND finger HSBP1 PF06825.7 KLO09180.1 - 6.2e-11 41.7 4.1 8.3e-11 41.2 2.8 1.2 1 0 0 1 1 1 1 Heat shock factor binding protein 1 PAP1 PF08601.5 KLO09180.1 - 0.023 14.4 2.7 0.027 14.1 1.9 1.1 1 0 0 1 1 1 0 Transcription factor PAP1 DUF2365 PF10157.4 KLO09180.1 - 0.027 14.3 0.1 0.03 14.2 0.1 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2365) DUF2130 PF09903.4 KLO09180.1 - 0.032 12.9 0.0 0.04 12.6 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2130) PMC2NT PF08066.7 KLO09180.1 - 0.037 14.3 0.4 0.075 13.3 0.0 1.7 2 0 0 2 2 2 0 PMC2NT (NUC016) domain NPV_P10 PF05531.7 KLO09180.1 - 0.046 13.9 0.4 0.067 13.4 0.3 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus P10 protein Baculo_PEP_C PF04513.7 KLO09180.1 - 0.074 12.8 0.1 0.091 12.5 0.0 1.2 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus BLOC1_2 PF10046.4 KLO09180.1 - 0.075 13.1 0.1 0.13 12.4 0.1 1.4 1 1 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 ApoO PF09769.4 KLO09180.1 - 0.088 12.5 0.0 0.1 12.3 0.0 1.1 1 0 0 1 1 1 0 Apolipoprotein O HsbA PF12296.3 KLO09180.1 - 0.2 11.5 2.3 1.7 8.4 1.3 2.0 1 1 1 2 2 2 0 Hydrophobic surface binding protein A Terpene_synth_C PF03936.11 KLO09181.1 - 9e-13 48.0 0.0 1.5e-12 47.2 0.0 1.3 1 0 0 1 1 1 1 Terpene synthase family, metal binding domain MFS_1 PF07690.11 KLO09183.1 - 6.6e-49 166.5 42.4 1.6e-47 161.9 30.8 2.0 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KLO09183.1 - 1.9e-14 53.0 13.7 1.9e-14 53.0 9.5 3.2 1 1 2 3 3 3 1 Sugar (and other) transporter TRI12 PF06609.8 KLO09183.1 - 5.4e-13 48.0 13.4 8.7e-13 47.3 9.3 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) IFT57 PF10498.4 KLO09183.1 - 0.036 12.7 0.1 0.057 12.1 0.1 1.2 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 E_Pc_C PF06752.7 KLO09184.1 - 0.027 13.9 0.3 0.039 13.4 0.2 1.2 1 0 0 1 1 1 0 Enhancer of Polycomb C-terminus Viral_Beta_CD PF04530.7 KLO09184.1 - 0.18 11.9 2.5 1.6 8.8 0.2 2.2 1 1 1 2 2 2 0 Viral Beta C/D like family DUF3357 PF11837.3 KLO09184.1 - 0.63 9.9 9.9 3.1 7.6 0.0 3.3 2 1 1 3 3 3 0 Domain of unknown function (DUF3357) MIP PF00230.15 KLO09185.1 - 2.6e-51 174.2 10.3 3.3e-51 173.9 7.2 1.1 1 0 0 1 1 1 1 Major intrinsic protein DUF4345 PF14248.1 KLO09186.1 - 0.023 14.1 2.2 0.06 12.8 1.5 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4345) DUF2721 PF11026.3 KLO09186.1 - 0.04 13.5 0.3 0.04 13.5 0.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2721) RPW8 PF05659.6 KLO09186.1 - 0.059 12.9 0.3 0.11 12.0 0.2 1.3 1 0 0 1 1 1 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 Multi_Drug_Res PF00893.14 KLO09186.1 - 3.9 7.9 7.5 6.6 7.2 0.2 2.4 2 0 0 2 2 2 0 Small Multidrug Resistance protein TrkH PF02386.11 KLO09187.1 - 1.2e-93 313.5 3.6 1.2e-93 313.5 2.5 2.1 2 0 0 2 2 2 2 Cation transport protein Oxysterol_BP PF01237.13 KLO09188.1 - 2.5e-53 180.8 0.2 6.7e-39 133.3 0.1 2.1 2 0 0 2 2 2 2 Oxysterol-binding protein Trp_oprn_chp PF09534.5 KLO09189.1 - 0.0015 18.2 0.0 0.0034 17.0 0.0 1.5 1 0 0 1 1 1 1 Tryptophan-associated transmembrane protein (Trp_oprn_chp) Gly-zipper_OmpA PF13436.1 KLO09189.1 - 1.9 8.1 8.3 0.18 11.4 2.2 2.0 2 0 0 2 2 2 0 Glycine-zipper containing OmpA-like membrane domain PEPcase PF00311.12 KLO09197.1 - 0.14 9.9 0.0 0.15 9.8 0.0 1.0 1 0 0 1 1 1 0 Phosphoenolpyruvate carboxylase CBFD_NFYB_HMF PF00808.18 KLO09204.1 - 6.9e-27 93.3 0.4 1.1e-26 92.7 0.3 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 KLO09204.1 - 7.9e-06 25.9 0.1 1.2e-05 25.2 0.0 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID-18kDa PF02269.11 KLO09204.1 - 0.0042 16.8 0.0 0.0071 16.1 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit SET PF00856.23 KLO09205.1 - 1.5e-08 35.0 0.7 1.5e-08 35.0 0.5 2.8 2 1 0 2 2 2 1 SET domain UDG PF03167.14 KLO09206.1 - 2.3e-19 69.3 0.0 2.9e-19 69.0 0.0 1.2 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily Sec63 PF02889.11 KLO09207.1 - 4.8e-194 643.6 0.0 6.9e-101 337.5 0.0 2.3 2 0 0 2 2 2 2 Sec63 Brl domain DEAD PF00270.24 KLO09207.1 - 3.2e-50 169.9 0.3 4.2e-28 97.9 0.1 3.1 3 0 0 3 3 3 2 DEAD/DEAH box helicase ResIII PF04851.10 KLO09207.1 - 3.1e-16 59.7 0.0 9.2e-11 41.9 0.0 3.0 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit Helicase_C PF00271.26 KLO09207.1 - 3e-11 43.0 0.0 2.6e-08 33.6 0.0 2.8 2 0 0 2 2 2 2 Helicase conserved C-terminal domain AAA_22 PF13401.1 KLO09207.1 - 6.4e-07 29.5 0.0 0.008 16.3 0.0 3.0 2 0 0 2 2 2 2 AAA domain PhoH PF02562.11 KLO09207.1 - 0.00028 20.1 0.0 0.052 12.7 0.0 2.4 2 0 0 2 2 2 2 PhoH-like protein AAA_19 PF13245.1 KLO09207.1 - 0.0046 16.6 0.0 0.67 9.7 0.0 2.6 2 0 0 2 2 2 1 Part of AAA domain Fungal_trans PF04082.13 KLO09208.1 - 1.5e-07 30.5 1.4 2.4e-07 29.9 1.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain WD40 PF00400.27 KLO09209.1 - 2.3e-16 58.9 10.6 0.0034 17.2 0.2 6.5 6 0 0 6 6 6 5 WD domain, G-beta repeat SRA1 PF07304.6 KLO09209.1 - 5.2e-07 29.5 0.0 5.2e-07 29.5 0.0 2.3 2 0 0 2 2 2 1 Steroid receptor RNA activator (SRA1) ATP_bind_1 PF03029.12 KLO09210.1 - 4.7e-73 245.6 0.0 5.7e-73 245.3 0.0 1.1 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein MMR_HSR1 PF01926.18 KLO09210.1 - 0.1 12.5 0.7 1.9 8.4 0.5 2.3 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_17 PF13207.1 KLO09210.1 - 0.6 10.9 6.9 0.26 12.1 1.4 2.7 2 1 0 2 2 2 0 AAA domain CPSF_A PF03178.10 KLO09211.1 - 1e-75 254.8 0.0 7e-75 252.0 0.0 2.2 2 0 0 2 2 2 1 CPSF A subunit region NTP_transf_5 PF14907.1 KLO09212.1 - 0.022 14.1 0.0 0.04 13.2 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised nucleotidyltransferase DEAD PF00270.24 KLO09213.1 - 2.4e-16 59.6 0.0 6.8e-16 58.2 0.0 1.8 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KLO09213.1 - 3.6e-15 55.5 0.1 7.6e-13 48.1 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DUF615 PF04751.9 KLO09213.1 - 0.00055 19.6 1.5 0.0012 18.4 1.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF615) ResIII PF04851.10 KLO09213.1 - 0.0043 16.9 0.0 0.0092 15.8 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit TMF_TATA_bd PF12325.3 KLO09213.1 - 0.0048 16.6 0.7 0.013 15.2 0.5 1.6 1 0 0 1 1 1 1 TATA element modulatory factor 1 TATA binding RQC PF09382.5 KLO09213.1 - 0.021 14.5 0.0 0.068 12.8 0.0 1.9 1 0 0 1 1 1 0 RQC domain V_ATPase_I PF01496.14 KLO09213.1 - 0.098 10.5 1.2 0.16 9.8 0.9 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Mnd1 PF03962.10 KLO09213.1 - 8.9 5.9 10.3 0.059 13.0 0.4 2.1 2 0 0 2 2 2 0 Mnd1 family PsbX PF06596.6 KLO09214.1 - 0.62 9.7 9.2 0.17 11.5 2.6 2.9 3 0 0 3 3 3 0 Photosystem II reaction centre X protein (PsbX) DUF202 PF02656.10 KLO09216.1 - 0.78 9.9 6.6 11 6.2 4.6 2.3 1 1 0 1 1 1 0 Domain of unknown function (DUF202) Abhydrolase_3 PF07859.8 KLO09222.1 - 1.7e-29 102.9 0.0 3.6e-22 78.9 0.0 2.4 2 0 0 2 2 2 2 alpha/beta hydrolase fold DUF2424 PF10340.4 KLO09222.1 - 0.00075 18.2 0.0 0.0012 17.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2424) DUF2034 PF10356.4 KLO09223.1 - 9.5e-33 112.9 0.0 1.1e-30 106.1 0.0 2.5 1 1 0 1 1 1 1 Protein of unknown function (DUF2034) Mrr_cat PF04471.7 KLO09223.1 - 1.2e-07 31.5 0.0 6.2e-07 29.2 0.0 1.9 1 1 0 1 1 1 1 Restriction endonuclease Trm112p PF03966.11 KLO09224.1 - 7e-21 74.3 0.1 9e-21 74.0 0.0 1.2 1 0 0 1 1 1 1 Trm112p-like protein zinc_ribbon_4 PF13717.1 KLO09224.1 - 0.032 13.9 0.1 0.067 12.8 0.1 1.6 1 0 0 1 1 1 0 zinc-ribbon domain zf-RING_4 PF14570.1 KLO09224.1 - 0.034 13.7 0.0 0.065 12.8 0.0 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zinc_ribbon_5 PF13719.1 KLO09224.1 - 0.035 13.7 0.1 0.083 12.4 0.1 1.6 1 0 0 1 1 1 0 zinc-ribbon domain zf-UDP PF14569.1 KLO09224.1 - 0.082 12.6 0.0 0.36 10.6 0.0 1.8 2 0 0 2 2 2 0 Zinc-binding RING-finger DUF334 PF03904.8 KLO09224.1 - 0.13 11.5 0.0 0.16 11.2 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF334) ARHGEF5_35 PF15441.1 KLO09227.1 - 0.29 9.8 2.4 0.34 9.6 1.7 1.2 1 1 0 1 1 1 0 Rho guanine nucleotide exchange factor 5/35 DUF605 PF04652.11 KLO09227.1 - 3.4 6.9 11.3 7.4 5.8 7.8 1.5 1 1 0 1 1 1 0 Vta1 like MAP65_ASE1 PF03999.7 KLO09227.1 - 5.1 5.5 10.5 5.2 5.5 7.3 1.0 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) PAT1 PF09770.4 KLO09229.1 - 1.5 6.9 4.3 1.9 6.6 3.0 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 zf-H2C2_2 PF13465.1 KLO09230.1 - 0.012 15.9 3.5 0.012 15.9 2.4 2.2 2 0 0 2 2 2 0 Zinc-finger double domain CW_binding_1 PF01473.15 KLO09230.1 - 0.23 11.6 2.1 0.48 10.6 1.4 1.6 1 0 0 1 1 1 0 Putative cell wall binding repeat zf-C2H2 PF00096.21 KLO09232.1 - 3.7e-12 45.8 9.1 0.00026 21.1 0.2 3.7 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KLO09232.1 - 5.8e-09 35.6 14.3 0.0011 19.1 0.2 3.9 3 1 0 3 3 3 3 C2H2-type zinc finger zf-H2C2_2 PF13465.1 KLO09232.1 - 8.1e-07 29.0 8.0 2.2e-05 24.4 0.1 4.1 3 1 0 3 3 3 1 Zinc-finger double domain zf-C2H2_6 PF13912.1 KLO09232.1 - 0.00093 19.0 1.6 1.1 9.2 0.0 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger Rtf2 PF04641.7 KLO09232.1 - 0.0051 16.0 0.5 0.21 10.7 0.1 2.1 2 0 0 2 2 2 1 Rtf2 RING-finger IBR PF01485.16 KLO09232.1 - 0.19 11.6 5.7 2.2 8.1 2.1 2.4 1 1 1 2 2 2 0 IBR domain Fer4_15 PF13459.1 KLO09232.1 - 0.46 11.0 3.5 0.26 11.8 0.8 1.8 2 0 0 2 2 2 0 4Fe-4S single cluster domain zf-met PF12874.2 KLO09232.1 - 1.4 9.1 5.0 8.3 6.7 0.1 3.6 3 0 0 3 3 3 0 Zinc-finger of C2H2 type PsbW PF07123.7 KLO09232.1 - 3.4 7.7 6.0 1 9.3 0.5 2.2 2 0 0 2 2 2 0 Photosystem II reaction centre W protein (PsbW) DnaJ PF00226.26 KLO09234.1 - 1.5e-05 24.6 0.0 1.7e-05 24.4 0.0 1.1 1 0 0 1 1 1 1 DnaJ domain Pam16 PF03656.8 KLO09234.1 - 0.00091 19.0 0.0 0.00094 18.9 0.0 1.0 1 0 0 1 1 1 1 Pam16 Carn_acyltransf PF00755.15 KLO09235.1 - 4.2e-133 444.5 0.0 4.9e-133 444.3 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase DUF3421 PF11901.3 KLO09236.1 - 8.5e-21 73.9 0.1 6.1e-19 67.9 0.0 2.3 1 1 0 1 1 1 1 Protein of unknown function (DUF3421) IncA PF04156.9 KLO09236.1 - 0.00016 21.3 0.0 0.00027 20.5 0.0 1.3 1 0 0 1 1 1 1 IncA protein CBM_5_12 PF02839.9 KLO09236.1 - 0.0015 18.1 0.5 0.0034 16.9 0.4 1.6 1 0 0 1 1 1 1 Carbohydrate binding domain ABA_WDS PF02496.11 KLO09236.1 - 0.026 14.6 2.5 0.03 14.4 0.6 1.7 1 1 1 2 2 2 0 ABA/WDS induced protein VIT1 PF01988.14 KLO09236.1 - 0.069 12.6 0.0 0.089 12.2 0.0 1.2 1 0 0 1 1 1 0 VIT family TPR_11 PF13414.1 KLO09238.1 - 6.1e-21 73.8 8.1 9.1e-11 41.2 0.3 4.0 2 2 1 4 4 4 3 TPR repeat TPR_1 PF00515.23 KLO09238.1 - 3.7e-18 64.2 4.3 0.00012 21.5 0.3 5.1 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_17 PF13431.1 KLO09238.1 - 1.2e-13 50.0 5.9 0.11 12.7 0.1 5.6 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_2 PF07719.12 KLO09238.1 - 4.5e-13 48.0 10.1 0.015 15.1 0.0 5.6 6 0 0 6 6 5 4 Tetratricopeptide repeat TPR_19 PF14559.1 KLO09238.1 - 4.5e-12 46.1 6.3 1.8e-05 24.9 0.0 4.4 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.1 KLO09238.1 - 1.9e-11 43.5 9.6 0.061 13.9 0.0 5.8 3 2 2 5 5 5 5 Tetratricopeptide repeat TPR_12 PF13424.1 KLO09238.1 - 8.6e-11 41.6 5.3 5.6e-05 22.9 0.3 3.8 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_16 PF13432.1 KLO09238.1 - 1.2e-09 38.6 10.5 1.2e-05 25.8 0.4 4.6 2 2 2 4 4 4 4 Tetratricopeptide repeat TPR_8 PF13181.1 KLO09238.1 - 1.1e-05 24.8 1.8 0.17 11.7 0.3 5.0 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_20 PF14561.1 KLO09238.1 - 3.1e-05 23.9 5.5 1.9 8.6 0.1 5.2 2 2 3 5 5 5 2 Tetratricopeptide repeat TPR_9 PF13371.1 KLO09238.1 - 6.5e-05 22.7 4.4 0.049 13.4 0.2 3.4 2 2 1 3 3 3 3 Tetratricopeptide repeat TPR_7 PF13176.1 KLO09238.1 - 0.0002 20.9 3.7 9.3 6.3 0.0 5.4 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_15 PF13429.1 KLO09238.1 - 0.00033 19.8 3.0 0.013 14.6 0.3 2.4 2 0 0 2 2 2 2 Tetratricopeptide repeat Apc3 PF12895.2 KLO09238.1 - 0.00035 20.6 2.0 0.017 15.2 0.3 2.6 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 APC_CDC26 PF10471.4 KLO09239.1 - 6e-05 23.7 10.0 0.00037 21.1 6.9 1.9 1 1 0 1 1 1 1 Anaphase-promoting complex APC subunit 1 DUF3379 PF11859.3 KLO09239.1 - 0.21 10.7 2.4 0.24 10.5 1.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3379) DUF2968 PF11180.3 KLO09239.1 - 0.36 10.2 8.1 0.38 10.1 5.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) Activator_LAG-3 PF11498.3 KLO09239.1 - 0.45 9.2 5.9 0.46 9.1 4.1 1.0 1 0 0 1 1 1 0 Transcriptional activator LAG-3 PRA1 PF03208.14 KLO09240.1 - 2e-38 131.1 0.4 2.4e-38 130.9 0.3 1.0 1 0 0 1 1 1 1 PRA1 family protein DUF3040 PF11239.3 KLO09240.1 - 0.0042 17.0 3.3 1 9.4 0.6 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF3040) DUF932 PF06067.6 KLO09240.1 - 0.11 11.7 0.0 0.14 11.4 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF932) 2TM PF13239.1 KLO09240.1 - 8 6.5 6.6 6.6 6.8 1.1 2.2 2 0 0 2 2 2 0 2TM domain PAS PF00989.19 KLO09241.1 - 0.00011 21.9 0.0 0.0002 21.1 0.0 1.4 1 0 0 1 1 1 1 PAS fold Zn_clus PF00172.13 KLO09241.1 - 0.00022 21.0 11.4 0.00045 20.0 7.9 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Methyltransf_26 PF13659.1 KLO09242.1 - 3.1e-14 53.0 0.0 1.2e-13 51.0 0.0 2.0 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 KLO09242.1 - 4.1e-08 33.7 0.0 1.6e-07 31.9 0.0 2.0 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 KLO09242.1 - 2.6e-07 30.3 0.0 9.6e-06 25.2 0.0 2.3 1 1 1 2 2 2 1 Methyltransferase domain MTS PF05175.9 KLO09242.1 - 1.8e-05 24.2 0.3 0.0004 19.7 0.2 2.2 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.1 KLO09242.1 - 2.2e-05 24.7 0.0 6.1e-05 23.3 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain UPF0020 PF01170.13 KLO09242.1 - 0.0005 19.6 0.1 0.024 14.2 0.0 2.3 1 1 1 2 2 2 1 Putative RNA methylase family UPF0020 PrmA PF06325.8 KLO09242.1 - 0.005 15.9 0.0 0.0085 15.2 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Cons_hypoth95 PF03602.10 KLO09242.1 - 0.0089 15.4 0.1 1.8 7.9 0.0 3.0 2 1 1 3 3 3 1 Conserved hypothetical protein 95 AviRa PF11599.3 KLO09242.1 - 0.013 14.5 0.0 0.019 13.9 0.0 1.3 1 0 0 1 1 1 0 RRNA methyltransferase AviRa Ubie_methyltran PF01209.13 KLO09242.1 - 0.027 13.5 0.0 0.056 12.5 0.0 1.5 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_11 PF08241.7 KLO09242.1 - 0.046 14.2 0.0 0.14 12.6 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_32 PF13679.1 KLO09242.1 - 0.057 13.0 0.0 0.098 12.3 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Tfb4 PF03850.9 KLO09243.1 - 4e-74 249.3 0.0 5e-74 249.0 0.0 1.1 1 0 0 1 1 1 1 Transcription factor Tfb4 zf-TRAF PF02176.13 KLO09244.1 - 2.7e-11 43.6 17.6 4.6e-07 30.1 2.1 4.6 1 1 3 5 5 5 3 TRAF-type zinc finger zf-RING_2 PF13639.1 KLO09244.1 - 3e-06 26.9 17.0 3e-06 26.9 11.8 3.6 2 1 0 2 2 1 1 Ring finger domain U-box PF04564.10 KLO09244.1 - 5.4e-06 26.2 0.1 6.8e-05 22.7 0.0 2.6 1 1 1 2 2 2 1 U-box domain zf-Nse PF11789.3 KLO09244.1 - 2.1e-05 23.9 9.6 2.1e-05 23.9 6.6 3.0 2 0 0 2 2 2 1 Zinc-finger of the MIZ type in Nse subunit zf-C3HC4_2 PF13923.1 KLO09244.1 - 3.3e-05 23.8 17.6 3.3e-05 23.8 12.2 4.2 3 1 1 4 4 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KLO09244.1 - 0.00023 20.7 18.1 0.00023 20.7 12.6 4.2 3 1 1 4 4 3 1 Zinc finger, C3HC4 type (RING finger) LRS4 PF10422.4 KLO09244.1 - 0.00033 20.0 0.2 0.0038 16.6 0.1 2.2 2 0 0 2 2 2 1 Monopolin complex subunit LRS4 zf-RING_UBOX PF13445.1 KLO09244.1 - 0.00058 19.5 11.3 0.00058 19.5 7.8 2.7 3 0 0 3 3 2 1 RING-type zinc-finger zf-RING_5 PF14634.1 KLO09244.1 - 0.00073 19.2 16.3 0.00073 19.2 11.3 3.7 2 1 1 3 3 2 1 zinc-RING finger domain zf-RING_6 PF14835.1 KLO09244.1 - 0.0013 18.4 6.9 0.0013 18.4 4.8 2.0 2 0 0 2 2 1 1 zf-RING of BARD1-type protein zf-rbx1 PF12678.2 KLO09244.1 - 0.0037 17.3 9.3 0.0037 17.3 6.4 3.5 3 0 0 3 3 2 1 RING-H2 zinc finger Sina PF03145.11 KLO09244.1 - 0.0072 16.0 19.6 0.14 11.7 1.3 3.5 1 1 1 3 3 3 3 Seven in absentia protein family zf-C3HC4_3 PF13920.1 KLO09244.1 - 0.0091 15.6 14.6 0.0091 15.6 10.1 3.8 3 1 2 5 5 5 1 Zinc finger, C3HC4 type (RING finger) CCDC144C PF14915.1 KLO09244.1 - 0.013 14.4 0.1 0.029 13.3 0.1 1.5 1 0 0 1 1 1 0 CCDC144C protein coiled-coil region Reo_sigmaC PF04582.7 KLO09244.1 - 0.31 10.1 2.5 11 5.1 0.3 2.2 2 0 0 2 2 2 0 Reovirus sigma C capsid protein Methyltransf_23 PF13489.1 KLO09245.1 - 1.2e-19 70.6 0.0 1.9e-19 69.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KLO09245.1 - 7.6e-14 51.5 0.0 6.3e-13 48.5 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KLO09245.1 - 7e-13 48.8 0.0 1.3e-12 48.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KLO09245.1 - 1e-09 38.9 0.0 9.3e-09 35.8 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KLO09245.1 - 1.1e-09 38.6 0.0 3.8e-09 36.9 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KLO09245.1 - 1.6e-07 31.6 0.0 4.5e-07 30.1 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 KLO09245.1 - 2e-06 26.9 0.0 3.4e-06 26.2 0.0 1.4 1 0 0 1 1 1 1 Putative methyltransferase GidB PF02527.10 KLO09245.1 - 0.00048 19.3 0.0 0.0016 17.6 0.0 1.7 1 1 0 1 1 1 1 rRNA small subunit methyltransferase G PrmA PF06325.8 KLO09245.1 - 0.0027 16.8 0.0 0.0052 15.9 0.0 1.5 1 1 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Ubie_methyltran PF01209.13 KLO09245.1 - 0.004 16.3 0.0 0.035 13.2 0.0 2.1 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_2 PF00891.13 KLO09245.1 - 0.0073 15.5 0.0 0.011 14.8 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase MTS PF05175.9 KLO09245.1 - 0.008 15.5 0.0 0.015 14.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_15 PF09445.5 KLO09245.1 - 0.013 15.0 0.0 0.028 13.9 0.0 1.5 2 0 0 2 2 2 0 RNA cap guanine-N2 methyltransferase Methyltransf_26 PF13659.1 KLO09245.1 - 0.017 15.1 0.0 0.076 13.0 0.0 2.0 1 1 0 1 1 1 0 Methyltransferase domain DUF938 PF06080.7 KLO09245.1 - 0.018 14.5 0.0 0.038 13.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF938) PCMT PF01135.14 KLO09245.1 - 0.041 13.4 0.0 0.088 12.3 0.0 1.5 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_17 PF12692.2 KLO09245.1 - 0.073 12.7 0.0 0.14 11.7 0.0 1.4 1 1 0 1 1 1 0 S-adenosyl-L-methionine methyltransferase RrnaAD PF00398.15 KLO09245.1 - 0.095 11.7 0.0 0.15 11.0 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Homeobox PF00046.24 KLO09247.1 - 7.6e-15 54.2 0.9 1.2e-14 53.6 0.6 1.3 1 0 0 1 1 1 1 Homeobox domain Pkinase PF00069.20 KLO09248.1 - 7.7e-45 153.0 0.0 1.1e-44 152.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KLO09248.1 - 2.1e-29 102.3 0.0 3e-29 101.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 KLO09248.1 - 0.00044 19.3 0.0 0.00074 18.6 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KLO09248.1 - 0.013 15.2 0.2 0.091 12.4 0.0 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family DUF1639 PF07797.9 KLO09248.1 - 0.087 12.2 2.5 0.089 12.2 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1639) TPP1 PF10341.4 KLO09249.1 - 1.9e-09 37.4 0.0 5.6e-09 35.9 0.0 1.8 1 0 0 1 1 1 1 Shelterin complex subunit, TPP1/ACD Ribosomal_S7 PF00177.16 KLO09251.1 - 3.5e-26 91.5 0.1 6.9e-26 90.6 0.1 1.4 2 0 0 2 2 2 1 Ribosomal protein S7p/S5e GPI-anchored PF10342.4 KLO09252.1 - 2.6e-08 34.2 1.0 2.6e-08 34.2 0.7 1.6 2 0 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family uDENN PF03456.13 KLO09252.1 - 0.037 13.9 0.0 0.069 13.1 0.0 1.4 1 0 0 1 1 1 0 uDENN domain CopC PF04234.7 KLO09252.1 - 0.11 13.1 0.1 13 6.4 0.0 2.2 1 1 1 2 2 2 0 CopC domain TMEM37 PF15108.1 KLO09253.1 - 0.023 14.3 0.3 0.023 14.3 0.2 2.5 1 1 0 2 2 2 0 Voltage-dependent calcium channel gamma-like subunit protein family COX14 PF14880.1 KLO09253.1 - 3.7 7.2 6.1 38 4.0 0.0 3.6 4 0 0 4 4 4 0 Cytochrome oxidase c assembly F-box-like PF12937.2 KLO09254.1 - 2.2e-06 27.2 0.5 4.7e-06 26.2 0.4 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KLO09254.1 - 0.045 13.4 0.6 0.19 11.4 0.4 2.1 2 0 0 2 2 2 0 F-box domain Lbh PF15317.1 KLO09255.1 - 0.11 12.7 0.0 0.22 11.8 0.0 1.4 1 0 0 1 1 1 0 Cardiac transcription factor regulator, Developmental protein O-antigen_lig PF13425.1 KLO09257.1 - 0.048 13.6 0.1 0.059 13.3 0.1 1.1 1 0 0 1 1 1 0 O-antigen ligase like membrane protein Fip1 PF05182.8 KLO09259.1 - 6e-20 70.2 0.5 9.7e-20 69.5 0.4 1.3 1 0 0 1 1 1 1 Fip1 motif VWA_3 PF13768.1 KLO09260.1 - 1.6e-24 86.4 0.0 3.1e-24 85.4 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.1 KLO09260.1 - 2.3e-19 70.1 0.0 7.2e-19 68.5 0.0 1.9 2 0 0 2 2 2 1 von Willebrand factor type A domain VIT PF08487.5 KLO09260.1 - 7.8e-19 67.5 0.0 1.5e-18 66.6 0.0 1.4 1 0 0 1 1 1 1 Vault protein inter-alpha-trypsin domain VWA PF00092.23 KLO09260.1 - 6.7e-15 55.2 0.0 1.7e-14 53.9 0.0 1.6 2 0 0 2 2 2 1 von Willebrand factor type A domain VIT_2 PF13757.1 KLO09260.1 - 1.9e-07 30.4 0.0 4.3e-07 29.3 0.0 1.5 1 0 0 1 1 1 1 Vault protein inter-alpha-trypsin domain VWA_CoxE PF05762.9 KLO09260.1 - 2.7e-06 26.6 0.1 4.8e-06 25.8 0.1 1.3 1 0 0 1 1 1 1 VWA domain containing CoxE-like protein vWA-TerF-like PF10138.4 KLO09260.1 - 0.00052 19.9 0.0 0.001 18.9 0.0 1.4 1 0 0 1 1 1 1 vWA found in TerF C terminus DUF2201 PF09967.4 KLO09260.1 - 0.022 14.7 0.0 0.099 12.6 0.0 2.1 1 1 0 1 1 1 0 VWA-like domain (DUF2201) PGI PF00342.14 KLO09260.1 - 0.027 12.9 0.2 0.055 11.8 0.1 1.4 1 0 0 1 1 1 0 Phosphoglucose isomerase Sulfate_tra_GLY PF13792.1 KLO09261.1 - 0.2 11.3 1.1 0.3 10.7 0.7 1.5 1 1 0 1 1 1 0 Sulfate transporter N-terminal domain with GLY motif RabGAP-TBC PF00566.13 KLO09262.1 - 3.5e-44 150.8 0.0 5e-44 150.3 0.0 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain VWA_2 PF13519.1 KLO09263.1 - 2e-09 37.7 0.4 2.7e-08 34.1 0.3 2.3 1 1 0 1 1 1 1 von Willebrand factor type A domain FAD_binding_4 PF01565.18 KLO09263.1 - 2.8e-09 36.5 1.2 4.8e-09 35.8 0.8 1.4 1 0 0 1 1 1 1 FAD binding domain VWA PF00092.23 KLO09263.1 - 1.9e-07 31.0 0.7 0.0041 16.8 0.0 2.5 2 0 0 2 2 2 2 von Willebrand factor type A domain vWA-TerF-like PF10138.4 KLO09263.1 - 0.00097 19.0 0.6 0.067 13.0 0.4 2.8 1 1 0 1 1 1 1 vWA found in TerF C terminus DUF3932 PF13068.1 KLO09264.1 - 0.013 15.6 0.6 0.021 14.9 0.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3932) IL4 PF00727.13 KLO09264.1 - 0.037 13.9 0.9 0.048 13.5 0.5 1.3 1 1 0 1 1 1 0 Interleukin 4 SIT PF15330.1 KLO09264.1 - 0.078 13.1 0.0 0.09 12.9 0.0 1.1 1 0 0 1 1 1 0 SHP2-interacting transmembrane adaptor protein, SIT FAD_binding_4 PF01565.18 KLO09265.1 - 3.3e-24 84.9 0.3 6.1e-24 84.0 0.2 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 KLO09265.1 - 0.0089 15.9 0.1 0.02 14.7 0.1 1.6 1 0 0 1 1 1 1 Berberine and berberine like Sigma70_ner PF04546.8 KLO09265.1 - 0.032 13.8 3.9 0.15 11.6 1.8 2.5 3 0 0 3 3 3 0 Sigma-70, non-essential region ADH_zinc_N PF00107.21 KLO09266.1 - 5.9e-33 113.1 0.0 9.7e-33 112.4 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 KLO09266.1 - 1e-13 52.3 0.0 2.4e-13 51.0 0.0 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KLO09266.1 - 2.5e-07 30.4 0.0 0.0001 21.9 0.0 2.5 1 1 1 2 2 2 2 Alcohol dehydrogenase GroES-like domain adh_short_C2 PF13561.1 KLO09266.1 - 0.0093 15.7 0.1 0.014 15.2 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase CMAS PF02353.15 KLO09266.1 - 0.016 14.3 0.1 0.023 13.7 0.1 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase DUF2431 PF10354.4 KLO09267.1 - 1.2e-37 129.3 0.0 6.4e-37 127.0 0.0 2.0 1 1 0 1 1 1 1 Domain of unknown function (DUF2431) PBP1_TM PF14812.1 KLO09267.1 - 3.2 8.1 5.5 2.2 8.6 0.3 2.4 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal RAMP4 PF06624.7 KLO09268.1 - 5.3e-09 35.4 0.0 7.3e-09 35.0 0.0 1.2 1 0 0 1 1 1 1 Ribosome associated membrane protein RAMP4 DUF3899 PF13038.1 KLO09268.1 - 0.031 14.4 0.0 0.038 14.1 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3899) DUF2970 PF11174.3 KLO09268.1 - 0.056 13.0 1.1 0.094 12.3 0.8 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2970) WD40 PF00400.27 KLO09269.1 - 1.2e-36 123.2 1.4 3.9e-09 36.0 0.1 6.5 7 0 0 7 7 7 5 WD domain, G-beta repeat CAF1C_H4-bd PF12265.3 KLO09269.1 - 4.7e-29 100.0 0.7 9.6e-29 99.0 0.5 1.6 1 0 0 1 1 1 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex ATP-synt_E PF05680.7 KLO09270.1 - 4.9e-19 68.0 0.1 5e-19 68.0 0.1 1.1 1 0 0 1 1 1 1 ATP synthase E chain DUF349 PF03993.7 KLO09270.1 - 0.58 10.3 5.4 0.89 9.7 3.7 1.3 1 1 0 1 1 1 0 Domain of Unknown Function (DUF349) BRCA-2_OB1 PF09103.5 KLO09271.1 - 4.5e-31 106.9 0.0 3.8e-30 103.9 0.0 2.1 2 0 0 2 2 2 1 BRCA2, oligonucleotide/oligosaccharide-binding, domain 1 BRCA-2_helical PF09169.5 KLO09271.1 - 1.2e-06 28.2 0.2 7.2e-06 25.7 0.1 2.0 2 0 0 2 2 2 1 BRCA2, helical UDPGP PF01704.13 KLO09272.1 - 3.6e-41 141.0 0.0 7.6e-41 139.9 0.0 1.4 1 1 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase NTP_transf_3 PF12804.2 KLO09272.1 - 0.1 12.6 0.0 0.22 11.5 0.0 1.5 1 0 0 1 1 1 0 MobA-like NTP transferase domain Taxilin PF09728.4 KLO09273.1 - 1.7e-12 47.0 39.7 2.8e-08 33.2 15.4 2.8 2 2 0 2 2 2 2 Myosin-like coiled-coil protein Rad60-SLD PF11976.3 KLO09273.1 - 0.0014 18.2 0.0 0.57 9.8 0.0 3.2 2 0 0 2 2 2 2 Ubiquitin-2 like Rad60 SUMO-like DUF4094 PF13334.1 KLO09273.1 - 0.61 10.5 12.2 4.3 7.7 3.9 3.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4094) Bacillus_HBL PF05791.6 KLO09273.1 - 0.72 9.1 15.8 0.26 10.6 7.8 2.4 2 1 1 3 3 3 0 Bacillus haemolytic enterotoxin (HBL) CENP-F_leu_zip PF10473.4 KLO09273.1 - 5.9 6.7 41.4 0.13 12.0 11.4 3.3 2 1 1 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 SUKH-4 PF14435.1 KLO09274.1 - 0.03 14.0 0.1 0.041 13.5 0.1 1.2 1 0 0 1 1 1 0 SUKH-4 immunity protein ADH_zinc_N PF00107.21 KLO09276.1 - 1.7e-29 101.9 0.0 2.7e-29 101.3 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 KLO09276.1 - 1.1e-13 52.2 0.0 2.4e-13 51.0 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KLO09276.1 - 1.4e-08 34.4 0.0 1.2e-06 28.2 0.0 2.4 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain FUN14 PF04930.10 KLO09276.1 - 0.041 14.1 0.1 0.99 9.7 0.0 2.7 3 0 0 3 3 3 0 FUN14 family CMAS PF02353.15 KLO09276.1 - 0.098 11.7 0.1 0.14 11.2 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase DSPc PF00782.15 KLO09276.1 - 0.13 11.8 0.0 0.78 9.3 0.0 2.0 2 0 0 2 2 2 0 Dual specificity phosphatase, catalytic domain DUF1793 PF08760.6 KLO09278.1 - 6.7e-29 100.9 0.0 1.1e-28 100.1 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1793) GBA2_N PF12215.3 KLO09278.1 - 0.0045 16.1 0.1 0.0081 15.3 0.1 1.4 1 0 0 1 1 1 1 beta-Glucocerebrosidase 2 N terminal Sad1_UNC PF07738.8 KLO09279.1 - 3e-06 27.0 0.0 0.0021 17.8 0.0 2.0 2 0 0 2 2 2 2 Sad1 / UNC-like C-terminal F5_F8_type_C PF00754.20 KLO09279.1 - 9.3e-05 22.2 0.0 0.00018 21.3 0.0 1.5 1 1 0 1 1 1 1 F5/8 type C domain zf-C2H2 PF00096.21 KLO09281.1 - 3.6e-10 39.5 17.2 3.4e-05 23.9 1.1 3.5 4 0 0 4 4 4 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 KLO09281.1 - 1.8e-07 31.0 2.5 1.8e-07 31.0 1.7 3.4 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.1 KLO09281.1 - 4.8e-07 29.6 13.7 0.0024 18.1 2.5 3.4 3 0 0 3 3 3 2 C2H2-type zinc finger NOA36 PF06524.7 KLO09281.1 - 7.3 5.7 11.6 0.18 11.0 1.1 2.1 2 0 0 2 2 2 0 NOA36 protein DUF2235 PF09994.4 KLO09282.1 - 3.7e-75 252.8 4.9 1.3e-74 251.1 3.4 1.8 1 1 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) Abhydrolase_5 PF12695.2 KLO09282.1 - 0.05 13.3 0.0 0.087 12.5 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family PIG-S PF10510.4 KLO09282.1 - 0.57 8.7 2.4 1.2 7.7 1.7 1.4 1 0 0 1 1 1 0 Phosphatidylinositol-glycan biosynthesis class S protein Apidaecin PF00807.12 KLO09287.1 - 0.15 11.7 2.3 0.23 11.1 1.6 1.2 1 0 0 1 1 1 0 Apidaecin Pox_M2 PF04887.7 KLO09294.1 - 0.0053 16.0 0.0 0.037 13.3 0.0 1.9 1 1 1 2 2 2 2 Poxvirus M2 protein Oxidored_q2 PF00420.19 KLO09296.1 - 0.11 12.1 2.9 0.12 11.9 2.0 1.2 1 0 0 1 1 1 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L MerE PF05052.7 KLO09296.1 - 0.23 11.4 1.5 0.27 11.2 1.0 1.2 1 0 0 1 1 1 0 MerE protein MetJ PF01340.15 KLO09299.1 - 0.11 12.2 0.0 0.12 12.1 0.0 1.3 1 0 0 1 1 1 0 Met Apo-repressor, MetJ Lipase_3 PF01764.20 KLO09300.1 - 6.4e-17 61.4 0.0 9.4e-17 60.9 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) FSH1 PF03959.8 KLO09300.1 - 0.062 12.7 0.0 0.12 11.8 0.0 1.4 1 0 0 1 1 1 0 Serine hydrolase (FSH1) Abhydrolase_6 PF12697.2 KLO09300.1 - 0.085 12.7 0.0 0.13 12.0 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family p450 PF00067.17 KLO09304.1 - 6.7e-59 199.6 0.0 8.6e-59 199.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 peroxidase PF00141.18 KLO09305.1 - 1.4e-27 96.6 0.0 2.6e-27 95.7 0.0 1.4 1 0 0 1 1 1 1 Peroxidase DUF3415 PF11895.3 KLO09305.1 - 1.1e-21 76.4 2.6 3e-21 75.0 1.8 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF3415) p450 PF00067.17 KLO09308.1 - 8.7e-61 205.8 0.0 1.2e-60 205.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 F-box-like PF12937.2 KLO09309.1 - 8.8e-08 31.7 0.0 2.4e-07 30.3 0.0 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KLO09309.1 - 0.0037 16.8 0.1 0.01 15.4 0.0 1.7 1 0 0 1 1 1 1 F-box domain DUF3450 PF11932.3 KLO09311.1 - 0.00073 18.8 0.1 0.00079 18.7 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3450) Snapin_Pallidin PF14712.1 KLO09311.1 - 0.0015 18.7 0.3 0.002 18.3 0.2 1.2 1 0 0 1 1 1 1 Snapin/Pallidin ADIP PF11559.3 KLO09311.1 - 0.0025 17.7 0.5 0.0032 17.3 0.4 1.1 1 0 0 1 1 1 1 Afadin- and alpha -actinin-Binding Nsp1_C PF05064.8 KLO09311.1 - 0.0053 16.3 0.5 0.0062 16.1 0.3 1.2 1 0 0 1 1 1 1 Nsp1-like C-terminal region Reo_sigmaC PF04582.7 KLO09311.1 - 0.0066 15.6 0.3 0.0074 15.5 0.2 1.0 1 0 0 1 1 1 1 Reovirus sigma C capsid protein THOC7 PF05615.8 KLO09311.1 - 0.011 16.0 0.6 0.011 15.9 0.4 1.1 1 0 0 1 1 1 0 Tho complex subunit 7 EzrA PF06160.7 KLO09311.1 - 0.014 13.5 0.9 0.016 13.4 0.7 1.0 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA CENP-F_leu_zip PF10473.4 KLO09311.1 - 0.016 15.0 1.8 0.016 15.0 1.2 1.5 1 1 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 CCDC155 PF14662.1 KLO09311.1 - 0.032 13.8 0.9 0.05 13.1 0.6 1.4 1 1 0 1 1 1 0 Coiled-coil region of CCDC155 DUF972 PF06156.8 KLO09311.1 - 0.034 14.4 1.8 0.057 13.7 0.8 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF972) Golgin_A5 PF09787.4 KLO09311.1 - 0.038 12.5 0.1 0.04 12.4 0.1 1.1 1 0 0 1 1 1 0 Golgin subfamily A member 5 DUF2968 PF11180.3 KLO09311.1 - 0.042 13.2 0.0 0.049 13.0 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) APG6 PF04111.7 KLO09311.1 - 0.043 12.8 0.4 0.045 12.7 0.3 1.0 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF948 PF06103.6 KLO09311.1 - 0.043 13.6 0.9 0.06 13.2 0.6 1.3 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF948) PspA_IM30 PF04012.7 KLO09311.1 - 0.074 12.4 0.7 0.088 12.1 0.5 1.2 1 0 0 1 1 1 0 PspA/IM30 family TBPIP PF07106.8 KLO09311.1 - 0.076 12.5 0.5 0.085 12.3 0.3 1.2 1 0 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Talin_middle PF09141.5 KLO09311.1 - 0.089 12.4 0.4 0.13 11.9 0.3 1.3 1 1 0 1 1 1 0 Talin, middle domain DUF2397 PF09660.5 KLO09311.1 - 0.091 11.3 0.1 0.093 11.2 0.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2397) DivIC PF04977.10 KLO09311.1 - 0.31 10.5 1.4 0.55 9.7 0.5 1.9 1 1 1 2 2 2 0 Septum formation initiator F-box-like PF12937.2 KLO09312.1 - 2.3e-09 36.8 0.3 2.2e-07 30.4 0.0 3.2 3 0 0 3 3 3 1 F-box-like F-box PF00646.28 KLO09312.1 - 0.00045 19.7 0.1 0.031 13.9 0.0 2.9 2 0 0 2 2 2 1 F-box domain Cation_efflux PF01545.16 KLO09314.1 - 7.2e-81 271.3 1.5 9.7e-81 270.9 1.0 1.2 1 0 0 1 1 1 1 Cation efflux family Zip PF02535.17 KLO09314.1 - 0.0067 15.4 3.6 0.015 14.3 2.5 1.6 1 1 0 1 1 1 1 ZIP Zinc transporter DUF2929 PF11151.3 KLO09314.1 - 0.85 9.7 7.0 4.8 7.3 0.2 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF2929) Med5 PF08689.5 KLO09315.1 - 6.7e-18 63.8 2.1 2.6e-14 51.9 1.0 2.5 3 0 0 3 3 3 2 Mediator complex subunit Med5 HicB PF05534.7 KLO09315.1 - 0.054 13.0 0.0 0.29 10.7 0.0 2.3 2 0 0 2 2 2 0 HicB family Nop10p PF04135.7 KLO09316.1 - 1e-20 73.1 0.1 1.3e-20 72.8 0.0 1.1 1 0 0 1 1 1 1 Nucleolar RNA-binding protein, Nop10p family Pro_isomerase PF00160.16 KLO09317.1 - 1.2e-42 145.7 0.0 1.9e-42 145.0 0.0 1.3 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Rtf2 PF04641.7 KLO09317.1 - 0.00011 21.4 0.0 0.00062 19.0 0.0 2.0 1 1 0 1 1 1 1 Rtf2 RING-finger U-box PF04564.10 KLO09317.1 - 0.0052 16.7 0.3 0.075 13.0 0.0 2.5 2 1 0 2 2 2 1 U-box domain Asp PF00026.18 KLO09318.1 - 1.8e-52 178.6 7.8 3.9e-52 177.4 5.4 1.5 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 KLO09318.1 - 9.9e-08 32.0 6.3 5e-06 26.5 4.4 2.9 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 KLO09318.1 - 0.00063 20.1 3.0 0.0064 16.9 0.4 2.5 2 0 0 2 2 2 1 Aspartyl protease TAXi_C PF14541.1 KLO09318.1 - 0.00067 19.2 0.1 0.003 17.1 0.0 2.1 2 1 0 2 2 2 1 Xylanase inhibitor C-terminal Asp PF00026.18 KLO09319.1 - 5.2e-42 144.1 6.9 1.7e-41 142.5 4.8 1.7 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 KLO09319.1 - 1.3e-07 31.7 4.5 6.9e-07 29.3 1.6 2.9 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal F-box PF00646.28 KLO09320.1 - 2.4e-06 27.0 0.3 5.9e-06 25.7 0.2 1.7 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 KLO09320.1 - 9.8e-05 22.0 0.4 0.00024 20.7 0.3 1.7 1 0 0 1 1 1 1 F-box-like Cucumo_2B PF03263.8 KLO09320.1 - 0.024 14.8 0.8 0.024 14.8 0.5 2.2 2 0 0 2 2 2 0 Cucumovirus protein 2B SMAP PF15477.1 KLO09320.1 - 0.05 13.8 0.2 0.19 12.0 0.0 2.1 2 0 0 2 2 2 0 Small acidic protein family BMFP PF04380.8 KLO09320.1 - 0.11 12.6 0.8 0.25 11.4 0.2 1.9 2 0 0 2 2 2 0 Membrane fusogenic activity F-box PF00646.28 KLO09321.1 - 4.8e-05 22.9 0.2 0.00013 21.5 0.2 1.7 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 KLO09321.1 - 0.03 14.0 0.1 0.078 12.7 0.1 1.7 1 0 0 1 1 1 0 F-box-like Ribul_P_3_epim PF00834.14 KLO09322.1 - 3.8e-64 215.4 0.0 4.6e-64 215.2 0.0 1.1 1 0 0 1 1 1 1 Ribulose-phosphate 3 epimerase family QRPTase_C PF01729.14 KLO09322.1 - 0.014 14.9 0.0 0.028 13.9 0.0 1.7 2 0 0 2 2 2 0 Quinolinate phosphoribosyl transferase, C-terminal domain PcrB PF01884.12 KLO09322.1 - 0.066 12.4 0.1 0.13 11.4 0.0 1.5 1 1 0 1 1 1 0 PcrB family Gly_transf_sug PF04488.10 KLO09323.1 - 5.2e-06 26.7 0.0 1.1e-05 25.7 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Caps_synth PF05704.7 KLO09323.1 - 0.037 13.1 0.2 0.059 12.5 0.2 1.2 1 0 0 1 1 1 0 Capsular polysaccharide synthesis protein ABC2_membrane PF01061.19 KLO09323.1 - 0.1 11.7 0.1 0.22 10.6 0.0 1.5 1 0 0 1 1 1 0 ABC-2 type transporter PK PF00224.16 KLO09324.1 - 4.1e-166 551.8 0.4 5.3e-166 551.4 0.3 1.1 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain PK_C PF02887.11 KLO09324.1 - 5.2e-33 113.0 0.0 4.5e-32 110.0 0.0 2.4 2 0 0 2 2 2 1 Pyruvate kinase, alpha/beta domain IMPDH PF00478.20 KLO09324.1 - 1.1e-05 24.4 0.2 0.00019 20.4 0.0 2.2 2 0 0 2 2 2 1 IMP dehydrogenase / GMP reductase domain HpcH_HpaI PF03328.9 KLO09324.1 - 4.4e-05 22.4 0.5 0.00013 20.9 0.4 1.8 1 1 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family LAG1-DNAbind PF09271.6 KLO09325.1 - 1.9e-25 89.9 0.3 8e-24 84.7 0.2 2.3 1 1 0 1 1 1 1 LAG1, DNA binding BTD PF09270.5 KLO09325.1 - 6.3e-24 84.5 0.0 1.1e-23 83.7 0.0 1.4 1 0 0 1 1 1 1 Beta-trefoil DNA-binding domain DUF4203 PF13886.1 KLO09329.1 - 6.9e-37 126.9 26.9 6.9e-37 126.9 18.6 1.8 2 1 0 2 2 2 1 Domain of unknown function (DUF4203) Mucin PF01456.12 KLO09329.1 - 2.1 8.1 35.6 0.012 15.3 18.4 1.8 2 0 0 2 2 2 0 Mucin-like glycoprotein DEAD PF00270.24 KLO09330.1 - 1.3e-18 67.0 0.0 5.4e-17 61.8 0.0 2.3 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KLO09330.1 - 0.0027 17.5 0.0 0.0056 16.5 0.0 1.7 1 1 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 KLO09330.1 - 0.068 12.9 0.0 0.14 11.9 0.0 1.5 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit RNase_PH PF01138.16 KLO09331.1 - 3.1e-19 69.6 1.2 4.1e-19 69.2 0.8 1.2 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.10 KLO09331.1 - 0.036 14.0 0.0 0.063 13.2 0.0 1.4 1 0 0 1 1 1 0 3' exoribonuclease family, domain 2 AA_permease PF00324.16 KLO09331.1 - 0.21 9.8 1.5 0.24 9.6 1.1 1.1 1 0 0 1 1 1 0 Amino acid permease Sugar_tr PF00083.19 KLO09332.1 - 1.1e-107 360.4 17.7 1.2e-107 360.2 12.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KLO09332.1 - 1.2e-32 113.0 45.1 5.6e-27 94.3 16.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1228 PF06779.9 KLO09332.1 - 1.3 9.0 6.6 0.4 10.7 0.2 3.1 4 0 0 4 4 4 0 Protein of unknown function (DUF1228) Sugar_tr PF00083.19 KLO09333.1 - 3.7e-104 348.8 16.4 4.4e-104 348.5 11.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KLO09333.1 - 6.7e-28 97.4 46.9 4.6e-27 94.6 15.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Cytochrom_D1 PF02239.11 KLO09334.1 - 0.33 9.1 0.0 2.3 6.4 0.0 2.1 2 0 0 2 2 2 0 Cytochrome D1 heme domain F-box PF00646.28 KLO09335.1 - 1.4e-05 24.5 0.3 1.4e-05 24.5 0.2 1.9 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.2 KLO09335.1 - 0.016 14.9 0.3 0.04 13.6 0.2 1.7 1 0 0 1 1 1 0 F-box-like DAO PF01266.19 KLO09336.1 - 3.4e-58 197.2 0.8 4.6e-58 196.8 0.6 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KLO09336.1 - 7.6e-05 22.6 0.4 0.00025 21.0 0.2 2.0 1 1 1 2 2 2 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 KLO09336.1 - 0.016 14.3 0.6 0.032 13.3 0.4 1.5 1 0 0 1 1 1 0 Thi4 family Pyr_redox PF00070.22 KLO09336.1 - 0.018 15.4 0.4 0.037 14.4 0.3 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 KLO09336.1 - 0.062 13.1 3.7 1.1 9.0 0.9 2.5 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 KLO09336.1 - 0.13 10.8 0.8 0.16 10.5 0.6 1.3 1 1 0 1 1 1 0 Tryptophan halogenase Enolase_C PF00113.17 KLO09337.1 - 6.7e-150 498.0 0.1 9.3e-150 497.5 0.1 1.1 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.11 KLO09337.1 - 3.3e-57 192.0 0.2 6.3e-57 191.1 0.2 1.5 1 0 0 1 1 1 1 Enolase, N-terminal domain MR_MLE_C PF13378.1 KLO09337.1 - 0.0018 18.2 0.0 0.0056 16.6 0.0 1.9 1 0 0 1 1 1 1 Enolase C-terminal domain-like MAAL_C PF07476.6 KLO09337.1 - 0.024 13.5 0.4 0.055 12.3 0.3 1.6 1 0 0 1 1 1 0 Methylaspartate ammonia-lyase C-terminus zf-MYND PF01753.13 KLO09338.1 - 3.7e-07 29.8 14.0 3.7e-07 29.8 9.7 1.8 2 0 0 2 2 2 1 MYND finger Snf7 PF03357.16 KLO09339.1 - 5.3e-38 130.0 19.0 6.2e-38 129.8 13.1 1.1 1 0 0 1 1 1 1 Snf7 DUF2851 PF11013.3 KLO09339.1 - 0.0017 17.1 4.4 0.0021 16.8 3.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2851) TraF_2 PF13729.1 KLO09339.1 - 0.057 12.2 0.2 0.057 12.2 0.1 1.7 2 0 0 2 2 2 0 F plasmid transfer operon, TraF, protein DUF458 PF04308.7 KLO09339.1 - 0.14 11.8 2.2 0.95 9.1 0.2 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF458) RbsD_FucU PF05025.8 KLO09339.1 - 0.15 12.3 3.8 0.12 12.6 1.3 1.8 1 1 0 1 1 1 0 RbsD / FucU transport protein family DUF2481 PF10654.4 KLO09339.1 - 4.4 7.0 8.3 0.26 10.9 1.4 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF2481) DUF2203 PF09969.4 KLO09339.1 - 10 6.3 10.9 1.1 9.5 0.9 2.1 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) Pneumo_att_G PF05539.6 KLO09340.1 - 4.8 6.4 21.5 6.5 6.0 14.9 1.1 1 0 0 1 1 1 0 Pneumovirinae attachment membrane glycoprotein G SRPRB PF09439.5 KLO09340.1 - 5.6 6.1 6.7 12 5.0 4.7 1.5 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit zf-RING_2 PF13639.1 KLO09341.1 - 5e-14 51.8 4.5 5e-14 51.8 3.1 1.6 2 0 0 2 2 1 1 Ring finger domain zf-rbx1 PF12678.2 KLO09341.1 - 4.6e-11 42.6 0.6 4.6e-11 42.6 0.4 1.5 2 0 0 2 2 1 1 RING-H2 zinc finger zf-C3HC4_3 PF13920.1 KLO09341.1 - 9.1e-07 28.4 1.5 9.1e-07 28.4 1.0 1.6 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KLO09341.1 - 2e-06 27.3 3.5 2e-06 27.3 2.4 1.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KLO09341.1 - 2.6e-06 27.0 2.3 2.6e-06 27.0 1.6 1.7 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 KLO09341.1 - 5.1e-06 26.4 4.6 1.1e-05 25.3 3.2 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 KLO09341.1 - 1.9e-05 24.3 0.4 3.6e-05 23.5 0.3 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.1 KLO09341.1 - 0.018 14.7 0.8 0.14 11.8 0.4 2.5 2 1 1 3 3 3 0 RING-type zinc-finger FANCL_C PF11793.3 KLO09341.1 - 0.17 11.8 3.5 0.73 9.8 2.4 1.9 1 1 0 1 1 1 0 FANCL C-terminal domain zf-RING_3 PF14369.1 KLO09341.1 - 0.22 11.5 0.1 0.22 11.5 0.0 2.4 3 0 0 3 3 3 0 zinc-finger zf-RING_4 PF14570.1 KLO09341.1 - 0.24 11.0 1.5 0.53 9.8 1.0 1.5 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain PHD PF00628.24 KLO09341.1 - 1.1 8.9 7.9 0.055 13.1 1.8 1.6 2 0 0 2 2 1 0 PHD-finger Prok-RING_1 PF14446.1 KLO09341.1 - 1.4 8.7 8.9 0.53 10.0 3.1 2.3 2 1 0 2 2 2 0 Prokaryotic RING finger family 1 zf-C3HC4_4 PF15227.1 KLO09341.1 - 1.7 8.5 4.2 4.5 7.2 2.9 1.8 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING Dicty_REP PF05086.7 KLO09341.1 - 6.1 4.4 9.4 8.4 4.0 6.5 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein DGF-1_C PF11040.3 KLO09344.1 - 0.073 12.9 7.9 1.2 9.0 1.8 2.4 2 1 0 2 2 2 0 Dispersed gene family protein 1 of Trypanosoma cruzi C-terminus TrbI PF03743.9 KLO09344.1 - 2.8 7.4 10.4 0.15 11.5 0.6 2.1 1 1 1 2 2 2 0 Bacterial conjugation TrbI-like protein SseC PF04888.7 KLO09344.1 - 7.3 5.8 21.8 13 5.0 15.1 1.4 1 1 0 1 1 1 0 Secretion system effector C (SseC) like family DUF1127 PF06568.6 KLO09345.1 - 1.6 8.1 4.3 3.2 7.2 3.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1127) zf-C2H2 PF00096.21 KLO09347.1 - 1.5e-08 34.4 9.3 4.3e-06 26.7 1.1 2.1 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 KLO09347.1 - 5.7e-08 32.6 14.2 1.7e-05 24.8 3.4 2.1 2 0 0 2 2 2 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 KLO09347.1 - 0.00039 20.5 10.9 0.0025 17.9 1.6 2.1 2 0 0 2 2 2 2 C2H2-type zinc finger zf-met PF12874.2 KLO09347.1 - 0.019 15.1 3.4 0.094 12.9 0.2 2.4 2 1 0 2 2 2 0 Zinc-finger of C2H2 type IBR PF01485.16 KLO09347.1 - 0.082 12.7 4.7 0.3 10.9 0.5 2.0 1 1 1 2 2 2 0 IBR domain zf-Dof PF02701.10 KLO09347.1 - 0.12 12.3 0.3 0.12 12.3 0.2 1.4 1 1 0 1 1 1 0 Dof domain, zinc finger Rad50_zn_hook PF04423.9 KLO09347.1 - 0.15 11.5 2.7 0.22 11.0 0.1 2.1 2 0 0 2 2 2 0 Rad50 zinc hook motif DUF2225 PF09986.4 KLO09347.1 - 0.23 10.8 1.9 0.24 10.8 1.3 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2225) zf-Di19 PF05605.7 KLO09347.1 - 0.39 10.8 5.9 0.61 10.2 4.1 1.5 1 1 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf-AN1 PF01428.11 KLO09347.1 - 0.89 9.4 5.8 8.4 6.3 0.3 2.9 2 1 1 3 3 3 0 AN1-like Zinc finger zf-C2H2_jaz PF12171.3 KLO09347.1 - 1.4 9.1 4.3 0.24 11.6 0.3 1.9 2 1 0 2 2 2 0 Zinc-finger double-stranded RNA-binding COMP PF11598.3 KLO09349.1 - 0.12 12.4 0.5 0.26 11.3 0.3 1.5 1 0 0 1 1 1 0 Cartilage oligomeric matrix protein Protein_K PF12283.3 KLO09350.1 - 0.091 12.6 0.0 0.16 11.8 0.0 1.4 1 0 0 1 1 1 0 Bacteriophage protein K SMN PF06003.7 KLO09355.1 - 0.0001 21.5 1.8 0.00032 19.8 0.9 1.8 2 0 0 2 2 2 1 Survival motor neuron protein (SMN) DUF3446 PF11928.3 KLO09355.1 - 8.3 6.6 8.8 9.4 6.5 5.1 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF3446) Chorion_2 PF03964.10 KLO09356.1 - 0.16 12.5 1.1 0.35 11.4 0.7 1.7 1 0 0 1 1 1 0 Chorion family 2 HHV6-IE PF03753.8 KLO09358.1 - 0.14 9.6 0.1 0.15 9.4 0.1 1.0 1 0 0 1 1 1 0 Human herpesvirus 6 immediate early protein G6B PF15096.1 KLO09359.1 - 0.016 14.7 0.1 0.017 14.6 0.1 1.1 1 0 0 1 1 1 0 G6B family FeoB_N PF02421.13 KLO09365.1 - 0.16 11.2 0.1 0.28 10.4 0.1 1.3 1 0 0 1 1 1 0 Ferrous iron transport protein B Cas_Csy2 PF09614.5 KLO09369.1 - 0.12 11.5 0.0 0.2 10.8 0.0 1.3 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Csy2) Phage_cap_E PF03864.10 KLO09371.1 - 0.042 12.7 0.0 0.072 12.0 0.0 1.3 1 0 0 1 1 1 0 Phage major capsid protein E DUF2975 PF11188.3 KLO09375.1 - 1.2 8.8 8.3 2.3 7.9 5.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2975) Glyco_hydro_20 PF00728.17 KLO09376.1 - 6.1e-89 298.6 0.0 7.3e-89 298.3 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Glycohydro_20b2 PF14845.1 KLO09376.1 - 3.3e-17 63.3 0.0 8e-17 62.1 0.0 1.7 1 0 0 1 1 1 1 beta-acetyl hexosaminidase like Glyco_hydro_20b PF02838.10 KLO09376.1 - 3.3e-07 30.8 0.1 6.1e-06 26.7 0.0 2.6 2 1 0 2 2 2 1 Glycosyl hydrolase family 20, domain 2 Flg_hook PF02120.11 KLO09376.1 - 0.14 11.8 0.0 0.37 10.4 0.0 1.7 1 0 0 1 1 1 0 Flagellar hook-length control protein FliK Pkinase PF00069.20 KLO09377.1 - 0.0013 17.9 0.0 0.0024 17.0 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain WaaY PF06176.6 KLO09377.1 - 0.004 16.4 0.0 0.0071 15.5 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide core biosynthesis protein (WaaY) APH PF01636.18 KLO09377.1 - 0.0071 16.0 0.0 0.012 15.3 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.17 KLO09377.1 - 0.017 14.4 0.0 0.033 13.5 0.0 1.4 1 0 0 1 1 1 0 RIO1 family Pkinase PF00069.20 KLO09382.1 - 2.2e-43 148.2 0.0 3e-43 147.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KLO09382.1 - 3.1e-37 128.0 0.0 4.4e-37 127.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.17 KLO09382.1 - 0.00016 21.1 0.0 0.00029 20.2 0.0 1.4 1 0 0 1 1 1 1 RIO1 family Kinase-like PF14531.1 KLO09382.1 - 0.017 14.1 0.0 0.027 13.4 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Mtp PF03821.11 KLO09390.1 - 0.086 12.2 3.9 0.27 10.6 1.8 2.1 2 0 0 2 2 2 0 Golgi 4-transmembrane spanning transporter DUF805 PF05656.9 KLO09390.1 - 3.9 7.3 13.8 8 6.3 0.1 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF805) Exotox-A_bind PF09101.5 KLO09393.1 - 0.1 11.7 0.0 0.15 11.1 0.0 1.2 1 0 0 1 1 1 0 Exotoxin A binding Pkinase PF00069.20 KLO09395.1 - 2.1e-41 141.8 0.0 1.3e-32 113.0 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 KLO09395.1 - 9.3e-26 90.4 0.0 9.6e-24 83.8 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 KLO09395.1 - 0.0096 14.9 0.0 1.5 7.7 0.0 2.2 2 0 0 2 2 2 2 Kinase-like RIO1 PF01163.17 KLO09395.1 - 0.1 11.9 0.0 0.25 10.6 0.0 1.6 1 0 0 1 1 1 0 RIO1 family Seadorna_VP7 PF07387.6 KLO09395.1 - 0.14 10.9 0.0 0.23 10.2 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 MukE PF04288.8 KLO09398.1 - 0.064 12.0 0.0 0.1 11.4 0.0 1.2 1 0 0 1 1 1 0 MukE-like family RPAP1_C PF08620.5 KLO09399.1 - 6.2e-21 74.0 0.0 1.3e-20 72.9 0.0 1.5 1 0 0 1 1 1 1 RPAP1-like, C-terminal RPAP1_N PF08621.5 KLO09399.1 - 2.8e-05 23.6 2.9 9e-05 21.9 2.0 1.9 1 0 0 1 1 1 1 RPAP1-like, N-terminal FadA PF09403.5 KLO09399.1 - 0.21 11.5 0.0 0.53 10.3 0.0 1.6 1 0 0 1 1 1 0 Adhesion protein FadA Methyltransf_2 PF00891.13 KLO09400.1 - 8.2e-29 100.4 0.0 2.4e-28 98.9 0.0 1.7 2 0 0 2 2 2 1 O-methyltransferase Methyltransf_12 PF08242.7 KLO09400.1 - 0.0007 20.0 0.0 0.0026 18.2 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KLO09400.1 - 0.0007 19.3 0.0 0.0016 18.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KLO09400.1 - 0.0056 16.0 0.0 0.011 15.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_18 PF12847.2 KLO09400.1 - 0.0079 16.7 0.0 0.026 15.0 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_16 PF10294.4 KLO09400.1 - 0.043 13.2 0.0 0.099 12.0 0.0 1.5 1 0 0 1 1 1 0 Putative methyltransferase Methyltransf_4 PF02390.12 KLO09400.1 - 0.058 12.4 0.0 0.1 11.6 0.0 1.4 1 0 0 1 1 1 0 Putative methyltransferase tRNA-synt_1c PF00749.16 KLO09401.1 - 1.3e-99 332.8 0.1 1.7e-99 332.4 0.1 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.13 KLO09401.1 - 1.2e-36 126.0 0.5 9e-36 123.1 0.0 2.1 2 0 0 2 2 2 1 tRNA synthetases class I (E and Q), anti-codon binding domain GST_C_2 PF13410.1 KLO09401.1 - 0.00067 19.5 0.1 0.0018 18.1 0.1 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 KLO09401.1 - 0.001 19.5 0.2 0.0039 17.6 0.1 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 KLO09401.1 - 0.022 14.7 0.0 0.061 13.3 0.0 1.7 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain tRNA-synt_1e PF01406.14 KLO09401.1 - 0.023 13.8 0.3 0.041 12.9 0.2 1.3 1 0 0 1 1 1 0 tRNA synthetases class I (C) catalytic domain Rad52_Rad22 PF04098.10 KLO09402.1 - 6.4e-60 201.3 0.0 7e-60 201.2 0.0 1.0 1 0 0 1 1 1 1 Rad52/22 family double-strand break repair protein F-box-like PF12937.2 KLO09404.1 - 3.2e-07 29.9 0.6 1.4e-06 27.8 0.4 2.2 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KLO09404.1 - 6e-07 28.9 0.5 1.5e-06 27.7 0.3 1.7 1 0 0 1 1 1 1 F-box domain PQQ_2 PF13360.1 KLO09404.1 - 0.086 12.2 0.0 0.49 9.8 0.0 2.0 1 1 1 2 2 2 0 PQQ-like domain PQQ PF01011.16 KLO09404.1 - 0.092 12.3 0.0 0.38 10.3 0.0 2.2 1 0 0 1 1 1 0 PQQ enzyme repeat Ribosomal_L14e PF01929.12 KLO09406.1 - 1e-29 102.6 0.2 1e-29 102.6 0.2 1.6 3 0 0 3 3 3 1 Ribosomal protein L14 KOW PF00467.24 KLO09406.1 - 5e-05 22.8 0.1 0.00013 21.5 0.1 1.7 1 0 0 1 1 1 1 KOW motif Amidase PF01425.16 KLO09407.1 - 8.2e-84 281.9 0.0 9.6e-84 281.7 0.0 1.0 1 0 0 1 1 1 1 Amidase Kinetochor_Ybp2 PF08568.5 KLO09408.1 - 1.4e-27 96.2 1.4 3.4e-20 71.8 0.0 2.2 2 0 0 2 2 2 2 Uncharacterised protein family, YAP/Alf4/glomulin HEAT_2 PF13646.1 KLO09408.1 - 0.032 14.5 0.1 0.46 10.7 0.0 2.9 3 0 0 3 3 3 0 HEAT repeats Bestrophin PF01062.16 KLO09409.1 - 2.5e-50 171.0 0.7 7.6e-28 97.2 0.1 2.1 2 0 0 2 2 2 2 Bestrophin, RFP-TM, chloride channel SET PF00856.23 KLO09410.1 - 1.9e-10 41.2 0.0 4.6e-08 33.5 0.0 2.4 1 1 0 1 1 1 1 SET domain zf-MYND PF01753.13 KLO09410.1 - 1.9e-08 34.0 17.2 1.9e-08 34.0 11.9 2.7 2 1 1 3 3 3 1 MYND finger Kdo PF06293.9 KLO09412.1 - 0.12 11.3 0.0 0.21 10.6 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kdo PF06293.9 KLO09419.1 - 0.1 11.6 0.0 0.15 11.0 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.20 KLO09419.1 - 0.15 11.1 0.0 0.21 10.7 0.0 1.1 1 0 0 1 1 1 0 Protein kinase domain AA_permease_2 PF13520.1 KLO09420.1 - 4.5e-71 239.6 38.1 5.9e-71 239.2 26.4 1.2 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 KLO09420.1 - 2.1e-19 69.2 30.5 2.8e-19 68.8 21.1 1.1 1 0 0 1 1 1 1 Amino acid permease CH PF00307.26 KLO09421.1 - 5.5e-70 232.2 0.0 3.5e-19 68.8 0.1 4.7 4 1 0 4 4 4 4 Calponin homology (CH) domain CAMSAP_CH PF11971.3 KLO09421.1 - 7.2e-07 28.7 0.0 4.6 6.9 0.0 4.8 5 0 0 5 5 5 3 CAMSAP CH domain TFIIA_gamma_C PF02751.9 KLO09422.1 - 7.8e-25 86.4 1.7 1.1e-24 86.0 1.2 1.2 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit TFIIA_gamma_N PF02268.11 KLO09422.1 - 3.8e-17 61.5 0.8 5.5e-17 61.0 0.5 1.3 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit, helical domain Na_Ca_ex PF01699.19 KLO09423.1 - 9.5e-37 125.7 29.5 5.8e-20 71.3 7.5 2.8 3 0 0 3 3 3 2 Sodium/calcium exchanger protein Acyl-thio_N PF12590.3 KLO09423.1 - 0.2 12.0 0.8 3.3 8.1 0.2 2.7 1 1 1 2 2 2 0 Acyl-ATP thioesterase ThiS PF02597.15 KLO09427.1 - 2.2e-07 31.2 0.0 2.8e-06 27.6 0.0 2.0 2 0 0 2 2 2 1 ThiS family zf-C2H2_4 PF13894.1 KLO09428.1 - 0.00032 20.8 2.7 0.2 12.0 0.0 2.9 3 0 0 3 3 3 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 KLO09428.1 - 0.11 12.8 6.5 3.5 8.0 0.1 3.8 4 0 0 4 4 4 0 Zinc-finger double domain zf-C2H2 PF00096.21 KLO09428.1 - 2 8.9 8.7 5.9 7.4 0.1 3.4 3 0 0 3 3 3 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KLO09429.1 - 0.012 15.9 1.5 7.3 7.1 0.0 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2_6 PF13912.1 KLO09429.1 - 0.027 14.3 0.1 0.063 13.2 0.0 1.6 1 0 0 1 1 1 0 C2H2-type zinc finger zf-C2H2 PF00096.21 KLO09429.1 - 0.27 11.6 3.8 2.4 8.6 0.6 2.9 3 0 0 3 3 3 0 Zinc finger, C2H2 type p450 PF00067.17 KLO09430.1 - 1.4e-56 191.9 0.0 9.4e-56 189.2 0.0 2.1 1 1 0 1 1 1 1 Cytochrome P450 DUF1769 PF08588.5 KLO09431.1 - 5.2e-16 58.3 0.0 8.8e-16 57.5 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1769) HGWP PF03578.10 KLO09433.1 - 3.4 7.0 6.4 13 5.1 4.1 2.0 2 0 0 2 2 2 0 HGWP repeat RNase_H PF00075.19 KLO09436.1 - 8.5e-09 35.8 0.0 1.1e-08 35.5 0.0 1.1 1 0 0 1 1 1 1 RNase H Pertussis_S2S3 PF02918.10 KLO09436.1 - 0.089 12.5 0.0 0.12 12.1 0.0 1.1 1 0 0 1 1 1 0 Pertussis toxin, subunit 2 and 3, C-terminal domain zf-C2H2_4 PF13894.1 KLO09437.1 - 0.00043 20.4 3.6 0.11 12.8 0.5 3.1 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.21 KLO09437.1 - 0.66 10.4 8.2 7.1 7.1 0.2 3.0 3 0 0 3 3 3 0 Zinc finger, C2H2 type Condensation PF00668.15 KLO09438.1 - 1.3e-06 27.5 0.0 2.7e-06 26.4 0.0 1.6 1 1 0 1 1 1 1 Condensation domain WD40 PF00400.27 KLO09440.1 - 4.5e-16 58.0 17.2 3.1e-05 23.6 0.2 5.1 6 0 0 6 6 6 3 WD domain, G-beta repeat eIF2A PF08662.6 KLO09440.1 - 0.16 11.6 0.0 2.8 7.5 0.0 2.5 2 0 0 2 2 2 0 Eukaryotic translation initiation factor eIF2A PGI PF00342.14 KLO09441.1 - 5.2e-213 707.8 0.1 6e-213 707.6 0.0 1.0 1 0 0 1 1 1 1 Phosphoglucose isomerase DUF4451 PF14616.1 KLO09443.1 - 5.3e-10 39.1 26.8 0.018 14.8 0.5 5.7 6 0 0 6 6 6 5 Domain of unknown function (DUF4451) DUF3279 PF11682.3 KLO09443.1 - 0.043 13.3 0.5 0.043 13.3 0.4 5.2 6 0 0 6 6 6 0 Protein of unknown function (DUF3279) MDFI PF15316.1 KLO09444.1 - 2.6 8.0 3.7 5.4 6.9 0.1 2.3 2 0 0 2 2 2 0 MyoD family inhibitor Transcrip_act PF04949.8 KLO09445.1 - 0.00081 19.0 1.7 0.54 9.8 1.1 2.4 1 1 1 2 2 2 2 Transcriptional activator Apolipoprotein PF01442.13 KLO09445.1 - 0.011 15.3 2.7 1.6e+02 1.6 0.4 1.8 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain Prefoldin_2 PF01920.15 KLO09445.1 - 0.012 15.3 3.1 0.77 9.5 0.0 2.4 1 1 1 2 2 2 0 Prefoldin subunit AATF-Che1 PF13339.1 KLO09445.1 - 0.03 14.4 0.6 0.043 13.9 0.4 1.3 1 1 0 1 1 1 0 Apoptosis antagonizing transcription factor LMP PF04778.7 KLO09445.1 - 0.032 13.9 0.4 0.042 13.5 0.3 1.1 1 0 0 1 1 1 0 LMP repeated region 6PF2K PF01591.13 KLO09445.1 - 0.044 12.8 0.3 0.066 12.2 0.1 1.4 2 0 0 2 2 2 0 6-phosphofructo-2-kinase DUF91 PF01939.11 KLO09445.1 - 0.071 12.2 0.2 0.076 12.1 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function DUF91 DUF1664 PF07889.7 KLO09445.1 - 0.14 11.9 0.7 0.35 10.6 0.5 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) DUF2408 PF10303.4 KLO09445.1 - 0.21 11.6 1.6 0.35 10.9 0.5 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF2408) DUF1640 PF07798.6 KLO09445.1 - 0.22 11.5 2.6 0.28 11.2 1.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1640) CHAT PF12770.2 KLO09446.1 - 5.1e-28 98.0 0.0 6.6e-28 97.6 0.0 1.1 1 0 0 1 1 1 1 CHAT domain PhdYeFM_antitox PF02604.14 KLO09446.1 - 0.031 13.8 0.0 0.084 12.4 0.0 1.8 1 0 0 1 1 1 0 Antitoxin Phd_YefM, type II toxin-antitoxin system CHAT PF12770.2 KLO09450.1 - 6.1e-28 97.7 0.0 9.5e-28 97.1 0.0 1.3 1 0 0 1 1 1 1 CHAT domain PCI PF01399.22 KLO09452.1 - 3.5e-05 24.0 0.0 8.5e-05 22.8 0.0 1.6 1 1 0 1 1 1 1 PCI domain LtrA PF06772.6 KLO09453.1 - 1.3e-05 24.2 10.7 0.0014 17.6 1.1 2.7 2 1 1 3 3 3 2 Bacterial low temperature requirement A protein (LtrA) FSH1 PF03959.8 KLO09457.1 - 7.6e-46 156.2 0.0 1.6e-45 155.1 0.0 1.5 2 0 0 2 2 2 1 Serine hydrolase (FSH1) Abhydrolase_5 PF12695.2 KLO09457.1 - 4.6e-08 32.9 0.0 1.4e-07 31.3 0.0 1.9 2 1 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KLO09457.1 - 0.00037 20.4 5.5 0.17 11.7 0.3 2.9 3 1 0 4 4 4 2 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 KLO09457.1 - 0.0096 15.1 0.0 0.38 9.9 0.0 2.3 2 0 0 2 2 2 1 Prolyl oligopeptidase family DLH PF01738.13 KLO09457.1 - 0.13 11.4 0.0 0.26 10.5 0.0 1.4 1 0 0 1 1 1 0 Dienelactone hydrolase family STE3 PF02076.10 KLO09458.1 - 6.6e-63 212.4 11.7 7.8e-63 212.1 8.1 1.1 1 0 0 1 1 1 1 Pheromone A receptor Abhydrolase_9_N PF15420.1 KLO09458.1 - 0.067 12.9 4.1 0.15 11.8 2.8 1.5 1 0 0 1 1 1 0 Alpha/beta-hydrolase family N-terminus STE3 PF02076.10 KLO09459.1 - 1.1e-56 192.0 9.9 1.3e-56 191.7 6.8 1.1 1 0 0 1 1 1 1 Pheromone A receptor 7tm_7 PF08395.7 KLO09459.1 - 0.0037 16.3 1.5 0.0037 16.3 1.0 2.5 3 0 0 3 3 3 1 7tm Chemosensory receptor STE3 PF02076.10 KLO09460.1 - 1.7e-59 201.2 12.3 2.1e-59 200.9 8.5 1.1 1 0 0 1 1 1 1 Pheromone A receptor PUCC PF03209.10 KLO09460.1 - 0.017 13.8 0.9 3.6 6.2 0.0 2.4 2 0 0 2 2 2 0 PUCC protein STE3 PF02076.10 KLO09461.1 - 1.3e-40 139.3 18.0 3.4e-21 75.5 0.2 2.1 1 1 1 2 2 2 2 Pheromone A receptor DUF1275 PF06912.6 KLO09462.1 - 1.5e-25 89.5 18.4 2e-25 89.2 12.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1275) RLI PF04068.10 KLO09462.1 - 0.15 11.6 0.1 0.24 11.0 0.1 1.3 1 0 0 1 1 1 0 Possible Fer4-like domain in RNase L inhibitor, RLI Phage_holin PF04688.8 KLO09462.1 - 3.5 7.2 4.7 0.66 9.5 0.2 2.0 2 0 0 2 2 2 0 Phage lysis protein, holin DUF2486 PF10667.4 KLO09463.1 - 0.11 12.9 6.3 0.18 12.3 4.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2486) Sporozoite_P67 PF05642.6 KLO09463.1 - 1.4 6.6 7.0 2.4 5.9 4.9 1.4 1 0 0 1 1 1 0 Sporozoite P67 surface antigen STE3 PF02076.10 KLO09464.1 - 5.6e-61 206.1 11.7 6.7e-61 205.8 8.1 1.1 1 0 0 1 1 1 1 Pheromone A receptor DUF4534 PF15049.1 KLO09464.1 - 0.0046 16.6 0.8 0.0097 15.5 0.5 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF4534) DUF3671 PF12420.3 KLO09464.1 - 0.023 14.6 1.5 1.2 9.1 0.1 2.7 2 1 0 2 2 2 0 Protein of unknown function STE3 PF02076.10 KLO09465.1 - 1.5e-50 171.8 14.5 1.8e-50 171.5 10.1 1.1 1 0 0 1 1 1 1 Pheromone A receptor Multi_Drug_Res PF00893.14 KLO09465.1 - 0.076 13.4 2.7 7.1 7.1 0.1 2.6 2 0 0 2 2 2 0 Small Multidrug Resistance protein STE3 PF02076.10 KLO09466.1 - 8.2e-14 51.3 6.8 8.8e-14 51.2 4.7 1.0 1 0 0 1 1 1 1 Pheromone A receptor Claudin_2 PF13903.1 KLO09466.1 - 0.074 12.7 2.0 0.086 12.5 1.4 1.0 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction STE3 PF02076.10 KLO09467.1 - 9.2e-31 106.9 4.7 1.1e-30 106.7 3.3 1.1 1 0 0 1 1 1 1 Pheromone A receptor 7tm_7 PF08395.7 KLO09467.1 - 0.055 12.4 3.5 0.082 11.9 2.4 1.3 1 1 0 1 1 1 0 7tm Chemosensory receptor Abhydrolase_6 PF12697.2 KLO09468.1 - 1.6e-20 74.0 2.8 2.3e-20 73.4 2.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KLO09468.1 - 1.3e-07 31.4 0.0 3e-07 30.2 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KLO09468.1 - 3.4e-07 30.0 0.1 2.9e-06 26.9 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold STE3 PF02076.10 KLO09469.1 - 3.3e-60 203.5 7.3 3.9e-60 203.3 5.0 1.0 1 0 0 1 1 1 1 Pheromone A receptor NACHT PF05729.7 KLO09471.1 - 1.3e-07 31.3 0.3 1.3e-06 28.1 0.0 2.4 2 0 0 2 2 2 1 NACHT domain AAA_16 PF13191.1 KLO09471.1 - 9.9e-06 25.6 0.0 0.00014 21.9 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain Arch_ATPase PF01637.13 KLO09471.1 - 0.0011 18.7 0.0 0.0077 15.9 0.0 2.2 2 0 0 2 2 2 1 Archaeal ATPase AAA_22 PF13401.1 KLO09471.1 - 0.0053 16.9 0.3 0.033 14.3 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.1 KLO09471.1 - 0.0063 16.3 0.0 0.013 15.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain NB-ARC PF00931.17 KLO09471.1 - 0.0094 14.8 0.0 0.023 13.5 0.0 1.6 1 0 0 1 1 1 1 NB-ARC domain AAA_17 PF13207.1 KLO09471.1 - 0.014 16.1 0.6 0.064 14.0 0.1 2.5 2 1 0 2 2 2 0 AAA domain APS_kinase PF01583.15 KLO09471.1 - 0.015 14.9 0.1 0.037 13.6 0.0 1.7 2 0 0 2 2 2 0 Adenylylsulphate kinase RNA_helicase PF00910.17 KLO09471.1 - 0.022 14.9 0.0 0.067 13.3 0.0 1.9 1 0 0 1 1 1 0 RNA helicase AAA_25 PF13481.1 KLO09471.1 - 0.03 13.7 0.1 0.075 12.4 0.1 1.6 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.1 KLO09471.1 - 0.043 13.5 0.0 0.098 12.4 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain AAA PF00004.24 KLO09471.1 - 0.053 13.7 2.0 0.33 11.1 0.1 2.9 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.11 KLO09471.1 - 0.11 11.7 0.1 0.22 10.7 0.1 1.4 1 0 0 1 1 1 0 PhoH-like protein SVA PF05326.6 KLO09471.1 - 0.13 12.0 2.2 2.2 8.0 0.2 2.4 1 1 1 2 2 2 0 Seminal vesicle autoantigen (SVA) WD40 PF00400.27 KLO09472.1 - 2.8e-23 80.8 5.0 8.9e-13 47.5 0.4 2.8 2 1 0 2 2 2 2 WD domain, G-beta repeat PD40 PF07676.7 KLO09472.1 - 0.0039 16.8 0.0 0.47 10.1 0.0 2.6 2 0 0 2 2 2 1 WD40-like Beta Propeller Repeat PQQ_3 PF13570.1 KLO09472.1 - 0.011 16.0 2.4 0.39 11.0 0.2 2.4 1 1 1 2 2 2 0 PQQ-like domain Nup160 PF11715.3 KLO09472.1 - 0.06 11.4 0.0 0.88 7.6 0.0 2.1 1 1 0 1 1 1 0 Nucleoporin Nup120/160 Proteasome_A_N PF10584.4 KLO09472.1 - 0.14 11.5 0.0 19 4.6 0.0 3.1 3 0 0 3 3 3 0 Proteasome subunit A N-terminal signature Amastin PF07344.6 KLO09473.1 - 0.079 12.5 3.7 0.064 12.8 1.4 1.7 2 0 0 2 2 2 0 Amastin surface glycoprotein FAM117 PF15388.1 KLO09474.1 - 0.061 12.5 5.9 0.27 10.4 0.2 2.0 1 1 1 2 2 2 0 Protein Family FAM117 DUF3154 PF11351.3 KLO09474.1 - 0.074 12.7 0.1 0.12 12.1 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3154) WD40 PF00400.27 KLO09476.1 - 1.5e-37 126.1 4.0 2.8e-12 46.0 0.0 4.0 3 0 0 3 3 3 3 WD domain, G-beta repeat NACHT PF05729.7 KLO09476.1 - 3.6e-06 26.7 0.0 1.1e-05 25.1 0.0 1.9 1 0 0 1 1 1 1 NACHT domain PQQ_3 PF13570.1 KLO09476.1 - 8.5e-06 25.8 2.7 0.1 12.8 0.1 3.6 3 0 0 3 3 3 2 PQQ-like domain AAA_16 PF13191.1 KLO09476.1 - 8.2e-05 22.6 0.0 0.00067 19.6 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain eIF2A PF08662.6 KLO09476.1 - 0.0002 21.1 0.0 0.00049 19.8 0.0 1.7 1 0 0 1 1 1 1 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 KLO09476.1 - 0.00034 18.9 0.0 1.4 6.9 0.0 3.0 1 1 2 3 3 3 2 Nucleoporin Nup120/160 AAA_33 PF13671.1 KLO09476.1 - 0.008 16.0 0.0 0.023 14.5 0.0 1.8 1 0 0 1 1 1 1 AAA domain PD40 PF07676.7 KLO09476.1 - 0.01 15.4 0.1 30 4.4 0.0 3.5 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat Arch_ATPase PF01637.13 KLO09476.1 - 0.018 14.7 0.0 0.057 13.0 0.0 1.9 1 0 0 1 1 1 0 Archaeal ATPase AAA_22 PF13401.1 KLO09476.1 - 0.02 15.0 0.1 0.072 13.2 0.0 2.0 1 0 0 1 1 1 0 AAA domain APS_kinase PF01583.15 KLO09476.1 - 0.03 13.9 0.0 0.073 12.7 0.0 1.6 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA_17 PF13207.1 KLO09476.1 - 0.036 14.8 0.0 0.15 12.9 0.0 2.2 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.1 KLO09476.1 - 0.041 13.2 0.3 0.099 12.0 0.2 1.6 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 KLO09476.1 - 0.055 13.6 1.0 0.12 12.5 0.0 2.1 2 0 0 2 2 1 0 RNA helicase AAA PF00004.24 KLO09476.1 - 0.068 13.3 0.7 0.59 10.3 0.1 2.9 3 1 0 3 3 2 0 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.1 KLO09476.1 - 0.071 12.8 0.0 0.18 11.5 0.0 1.7 1 0 0 1 1 1 0 Part of AAA domain AAA_16 PF13191.1 KLO09480.1 - 8.7e-06 25.8 0.0 9.9e-06 25.6 0.0 1.1 1 0 0 1 1 1 1 AAA ATPase domain NACHT PF05729.7 KLO09480.1 - 2.3e-05 24.0 1.3 4.4e-05 23.2 0.9 1.5 1 1 0 1 1 1 1 NACHT domain AAA_33 PF13671.1 KLO09480.1 - 0.00098 19.0 0.0 0.0011 18.8 0.0 1.2 1 0 0 1 1 1 1 AAA domain Arch_ATPase PF01637.13 KLO09480.1 - 0.0013 18.4 0.0 0.0013 18.4 0.0 1.1 1 0 0 1 1 1 1 Archaeal ATPase AAA_22 PF13401.1 KLO09480.1 - 0.0016 18.5 0.0 0.002 18.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain NB-ARC PF00931.17 KLO09480.1 - 0.0023 16.8 0.0 0.0025 16.7 0.0 1.1 1 0 0 1 1 1 1 NB-ARC domain APS_kinase PF01583.15 KLO09480.1 - 0.0024 17.5 0.0 0.0031 17.1 0.0 1.2 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_25 PF13481.1 KLO09480.1 - 0.0027 17.1 0.1 0.0039 16.6 0.1 1.3 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 KLO09480.1 - 0.0038 16.9 0.0 0.0054 16.4 0.0 1.4 1 0 0 1 1 1 1 Part of AAA domain AAA_17 PF13207.1 KLO09480.1 - 0.0039 18.0 0.2 0.0047 17.7 0.2 1.5 1 1 0 1 1 1 1 AAA domain RNA_helicase PF00910.17 KLO09480.1 - 0.0039 17.3 0.0 0.0056 16.8 0.0 1.3 1 0 0 1 1 1 1 RNA helicase PhoH PF02562.11 KLO09480.1 - 0.012 14.8 0.1 0.017 14.4 0.0 1.1 1 0 0 1 1 1 0 PhoH-like protein AAA_29 PF13555.1 KLO09480.1 - 0.016 14.7 0.1 0.029 13.9 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_tran PF00005.22 KLO09480.1 - 0.019 15.2 0.0 0.034 14.4 0.0 1.3 1 1 0 1 1 1 0 ABC transporter AAA PF00004.24 KLO09480.1 - 0.03 14.5 0.0 0.034 14.3 0.0 1.3 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.1 KLO09480.1 - 0.052 13.1 0.0 0.084 12.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain PIF1 PF05970.9 KLO09480.1 - 0.12 11.2 0.0 0.15 11.0 0.0 1.1 1 0 0 1 1 1 0 PIF1-like helicase AAA_18 PF13238.1 KLO09480.1 - 0.12 12.6 0.6 0.15 12.3 0.4 1.5 1 1 0 1 1 1 0 AAA domain WD40 PF00400.27 KLO09481.1 - 7.3e-85 276.1 14.4 4e-12 45.5 0.0 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat PD40 PF07676.7 KLO09481.1 - 1.6e-13 49.9 0.3 0.71 9.5 0.0 7.3 7 0 0 7 7 7 2 WD40-like Beta Propeller Repeat PQQ_2 PF13360.1 KLO09481.1 - 1.1e-12 47.9 1.5 9.2e-07 28.5 0.1 4.0 1 1 0 2 2 2 2 PQQ-like domain Nup160 PF11715.3 KLO09481.1 - 5.8e-12 44.5 1.1 0.087 10.9 0.0 5.8 2 2 4 6 6 6 3 Nucleoporin Nup120/160 PQQ_3 PF13570.1 KLO09481.1 - 3.1e-11 43.1 10.7 1.4 9.2 0.1 7.1 5 2 2 7 7 7 3 PQQ-like domain eIF2A PF08662.6 KLO09481.1 - 5.9e-11 42.4 0.0 0.0011 18.7 0.0 3.6 1 1 1 3 3 3 3 Eukaryotic translation initiation factor eIF2A Cytochrom_D1 PF02239.11 KLO09481.1 - 2.6e-06 26.0 0.5 0.0089 14.3 0.0 3.3 1 1 3 4 4 4 2 Cytochrome D1 heme domain Proteasome_A_N PF10584.4 KLO09481.1 - 5.3e-06 25.6 0.0 44 3.5 0.0 7.1 7 0 0 7 7 7 0 Proteasome subunit A N-terminal signature DsbC_N PF10411.4 KLO09481.1 - 1.5e-05 24.1 4.7 44 3.4 0.0 6.9 7 0 0 7 7 7 0 Disulfide bond isomerase protein N-terminus Peptidase_S9_N PF02897.10 KLO09481.1 - 0.00021 19.9 0.0 14 4.1 0.0 5.2 1 1 6 7 7 7 0 Prolyl oligopeptidase, N-terminal beta-propeller domain Nucleoporin_N PF08801.6 KLO09481.1 - 0.0019 17.0 0.2 20 3.7 0.1 4.5 1 1 1 3 3 3 0 Nup133 N terminal like PQQ PF01011.16 KLO09481.1 - 0.0029 17.0 6.1 5.1 6.8 0.0 6.1 7 0 0 7 7 7 1 PQQ enzyme repeat Me-amine-dh_H PF06433.6 KLO09481.1 - 0.0034 16.0 0.0 4.1 5.9 0.0 3.9 2 2 2 5 5 5 1 Methylamine dehydrogenase heavy chain (MADH) Nbas_N PF15492.1 KLO09481.1 - 0.018 14.1 0.6 11 4.9 0.0 4.5 5 2 2 7 7 7 0 Neuroblastoma-amplified sequence, N terminal DUF3313 PF11769.3 KLO09481.1 - 0.13 11.6 0.0 3.2 7.0 0.0 3.0 3 2 1 4 4 4 0 Protein of unknown function (DUF3313) DUF3312 PF11768.3 KLO09481.1 - 0.14 10.3 0.0 14 3.7 0.0 3.4 1 1 4 5 5 5 0 Protein of unknown function (DUF3312) Toxin_64 PF15542.1 KLO09481.1 - 8.6 6.9 7.6 3.3e+02 1.9 0.0 4.7 5 0 0 5 5 5 0 Putative toxin 64 Amastin PF07344.6 KLO09482.1 - 0.014 15.0 1.8 0.018 14.6 0.6 1.7 2 0 0 2 2 2 0 Amastin surface glycoprotein SPC25 PF06703.6 KLO09484.1 - 0.2 11.2 2.8 0.2 11.2 0.7 1.8 2 0 0 2 2 2 0 Microsomal signal peptidase 25 kDa subunit (SPC25) Tn7_Tnp_TnsA_C PF08721.6 KLO09486.1 - 0.13 12.2 0.0 0.2 11.6 0.0 1.3 1 0 0 1 1 1 0 TnsA endonuclease C terminal Mg_trans_NIPA PF05653.9 KLO09488.1 - 3.9e-20 72.0 18.2 3.6e-12 45.8 3.0 2.1 2 0 0 2 2 2 2 Magnesium transporter NIPA EamA PF00892.15 KLO09488.1 - 0.0018 18.3 11.1 0.0018 18.3 7.7 3.5 3 1 0 3 3 3 2 EamA-like transporter family DUF1510 PF07423.6 KLO09488.1 - 0.0051 16.2 0.2 0.0087 15.4 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1510) DUF962 PF06127.6 KLO09488.1 - 0.045 13.6 2.8 2.9 7.8 0.1 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF962) Neur_chan_memb PF02932.11 KLO09488.1 - 0.068 13.0 0.0 0.16 11.8 0.0 1.6 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region CDC45 PF02724.9 KLO09488.1 - 0.21 9.5 1.7 0.27 9.2 1.2 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF788 PF05620.6 KLO09488.1 - 1.5 8.6 5.6 4.5 7.0 0.2 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF788) DUF1761 PF08570.5 KLO09488.1 - 1.6 8.7 13.5 0.27 11.2 3.5 3.0 2 1 0 2 2 2 0 Protein of unknown function (DUF1761) Ycf1 PF05758.7 KLO09490.1 - 0.13 10.0 0.0 0.17 9.5 0.0 1.1 1 0 0 1 1 1 0 Ycf1 Apolipoprotein PF01442.13 KLO09492.1 - 0.0016 17.9 3.2 0.0035 16.8 2.2 1.5 1 1 0 1 1 1 1 Apolipoprotein A1/A4/E domain DUF4366 PF14283.1 KLO09492.1 - 0.0054 16.1 1.1 0.008 15.6 0.0 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF4366) DUF4131 PF13567.1 KLO09492.1 - 0.1 11.9 0.0 0.13 11.6 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) Methyltransf_14 PF08484.6 KLO09492.1 - 0.12 11.9 4.2 0.14 11.7 2.0 1.6 1 1 1 2 2 2 0 C-methyltransferase C-terminal domain Mito_fiss_reg PF05308.6 KLO09492.1 - 0.56 9.5 7.9 0.24 10.7 3.9 1.6 1 1 0 1 1 1 0 Mitochondrial fission regulator DUF4407 PF14362.1 KLO09492.1 - 0.94 8.3 16.0 1.6 7.6 11.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) GEMIN8 PF15348.1 KLO09492.1 - 1 9.4 7.1 0.59 10.1 3.6 1.5 1 1 0 1 1 1 0 Gemini of Cajal bodies-associated protein 8 Hydrolase_like PF13242.1 KLO09493.1 - 8.6e-23 79.8 0.0 2e-22 78.6 0.0 1.6 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase_6 PF13344.1 KLO09493.1 - 3.5e-22 78.1 0.0 6.2e-22 77.3 0.0 1.4 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 KLO09493.1 - 4.9e-07 30.1 0.0 9.5e-05 22.6 0.0 2.5 2 0 0 2 2 2 2 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 KLO09493.1 - 1.6e-06 28.6 0.0 1.6e-05 25.4 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase DUF1768 PF08719.6 KLO09494.1 - 1.1e-32 112.9 0.0 1.2e-32 112.7 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1768) Sec2p PF06428.6 KLO09496.1 - 2.7e-09 36.8 15.2 1.5e-08 34.3 9.3 2.5 2 1 0 2 2 2 1 GDP/GTP exchange factor Sec2p MAD PF05557.8 KLO09496.1 - 0.067 11.2 17.9 0.0042 15.2 7.4 1.9 2 0 0 2 2 2 0 Mitotic checkpoint protein DUF3813 PF12758.2 KLO09496.1 - 0.6 10.2 5.1 0.74 9.9 1.7 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3813) HAUS6_N PF14661.1 KLO09496.1 - 3.2 7.0 13.3 0.17 11.2 5.5 1.6 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 6 N-terminus Exonuc_VII_L PF02601.10 KLO09496.1 - 3.7 6.6 9.5 0.66 9.1 3.1 1.9 2 0 0 2 2 2 0 Exonuclease VII, large subunit Peptidase_M22 PF00814.20 KLO09497.1 - 1.1e-70 238.2 0.0 1.3e-70 237.9 0.0 1.0 1 0 0 1 1 1 1 Glycoprotease family FGGY_C PF02782.11 KLO09497.1 - 0.08 12.5 0.0 0.16 11.5 0.0 1.6 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, C-terminal domain GMC_oxred_N PF00732.14 KLO09498.1 - 1.9e-64 217.6 0.0 2.6e-64 217.2 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 KLO09498.1 - 3.1e-37 128.0 0.2 5.5e-37 127.2 0.2 1.4 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 KLO09498.1 - 9e-06 24.8 1.3 9e-05 21.5 0.1 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 KLO09498.1 - 8.5e-05 22.7 0.1 0.11 12.5 0.1 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 KLO09498.1 - 0.00021 20.3 0.0 0.00034 19.6 0.0 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_8 PF13450.1 KLO09498.1 - 0.00036 20.5 0.3 0.00099 19.0 0.2 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 KLO09498.1 - 0.00051 19.9 0.2 0.0019 18.0 0.0 2.0 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 KLO09498.1 - 0.00084 18.2 1.6 0.0014 17.5 0.4 1.8 2 0 0 2 2 2 1 FAD binding domain Pyr_redox PF00070.22 KLO09498.1 - 0.015 15.7 0.4 0.14 12.5 0.1 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 KLO09498.1 - 0.016 13.7 0.2 0.03 12.8 0.1 1.5 2 0 0 2 2 2 0 HI0933-like protein HHH_2 PF12826.2 KLO09498.1 - 0.044 13.6 0.0 0.17 11.7 0.0 2.0 2 0 0 2 2 1 0 Helix-hairpin-helix motif NAD_binding_9 PF13454.1 KLO09498.1 - 0.058 13.1 0.2 0.26 11.0 0.1 2.0 2 0 0 2 2 2 0 FAD-NAD(P)-binding TrkA_N PF02254.13 KLO09498.1 - 0.073 13.0 0.0 0.18 11.7 0.0 1.7 1 0 0 1 1 1 0 TrkA-N domain Thi4 PF01946.12 KLO09498.1 - 0.11 11.6 0.3 0.23 10.5 0.2 1.5 1 0 0 1 1 1 0 Thi4 family GMC_oxred_N PF00732.14 KLO09499.1 - 3.4e-61 206.9 0.0 4.4e-61 206.6 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 KLO09499.1 - 6.1e-36 123.8 0.1 1e-35 123.1 0.1 1.4 1 0 0 1 1 1 1 GMC oxidoreductase Pyr_redox_3 PF13738.1 KLO09499.1 - 8.7e-06 25.9 0.3 0.09 12.8 0.1 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 KLO09499.1 - 5.3e-05 22.2 1.5 8.5e-05 21.6 0.1 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 KLO09499.1 - 0.00018 20.5 0.0 0.00028 19.9 0.0 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_binding_2 PF00890.19 KLO09499.1 - 0.00065 18.6 0.4 0.00065 18.6 0.3 1.6 2 0 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.1 KLO09499.1 - 0.0015 18.4 0.1 0.0049 16.8 0.1 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 KLO09499.1 - 0.0016 18.3 0.0 0.004 17.0 0.0 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.13 KLO09499.1 - 0.056 13.4 0.1 0.19 11.7 0.0 1.9 2 0 0 2 2 2 0 TrkA-N domain NAD_binding_9 PF13454.1 KLO09499.1 - 0.06 13.1 0.2 0.42 10.3 0.1 2.3 3 0 0 3 3 3 0 FAD-NAD(P)-binding HI0933_like PF03486.9 KLO09499.1 - 0.066 11.6 0.4 0.15 10.4 0.1 1.6 2 0 0 2 2 2 0 HI0933-like protein BTB PF00651.26 KLO09500.1 - 5.6e-05 23.1 0.0 0.00013 21.9 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain Lipase_3 PF01764.20 KLO09501.1 - 1.2e-13 50.8 0.0 1.7e-13 50.3 0.0 1.2 1 0 0 1 1 1 1 Lipase (class 3) AXE1 PF05448.7 KLO09501.1 - 0.067 11.6 0.0 0.14 10.6 0.0 1.4 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) Oxidored_FMN PF00724.15 KLO09502.1 - 2e-77 260.4 0.0 2.5e-77 260.1 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Rhabdo_NV PF02484.10 KLO09502.1 - 0.11 12.3 0.1 0.41 10.5 0.0 1.8 2 0 0 2 2 2 0 Rhabdovirus Non-virion protein Peptidase_M73 PF12389.3 KLO09505.1 - 0.15 11.5 0.1 0.25 10.7 0.0 1.2 1 0 0 1 1 1 0 Camelysin metallo-endopeptidase LRR_8 PF13855.1 KLO09510.1 - 0.12 12.1 2.1 17 5.2 0.0 3.5 3 0 0 3 3 3 0 Leucine rich repeat Glyoxal_oxid_N PF07250.6 KLO09513.1 - 1.1e-34 119.6 0.2 5.2e-33 114.1 0.0 3.3 3 1 0 3 3 3 1 Glyoxal oxidase N-terminus DUF1929 PF09118.6 KLO09513.1 - 2.4e-21 75.6 0.9 4.6e-21 74.7 0.7 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1929) Herpes_gE PF02480.11 KLO09513.1 - 0.0042 15.4 0.1 0.015 13.6 0.0 1.7 2 0 0 2 2 2 1 Alphaherpesvirus glycoprotein E DUF1214 PF06742.6 KLO09513.1 - 0.024 15.1 0.1 0.086 13.3 0.0 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1214) CD99L2 PF12301.3 KLO09513.1 - 0.35 10.5 3.0 0.79 9.3 2.1 1.5 1 0 0 1 1 1 0 CD99 antigen like protein 2 DUF3246 PF11596.3 KLO09513.1 - 2.2 7.4 9.3 5.2 6.2 6.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3246) p450 PF00067.17 KLO09515.1 - 1.9e-74 250.8 0.0 2.2e-74 250.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF1129 PF06570.6 KLO09516.1 - 0.0024 17.1 6.7 0.062 12.6 2.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF1129) DUF485 PF04341.7 KLO09516.1 - 0.03 14.0 0.2 0.03 14.0 0.1 2.5 2 1 0 2 2 2 0 Protein of unknown function, DUF485 FA_desaturase PF00487.19 KLO09516.1 - 8 5.8 8.9 0.93 8.8 2.6 1.9 1 1 1 2 2 2 0 Fatty acid desaturase Fungal_trans PF04082.13 KLO09517.1 - 7.3e-18 64.3 0.3 1.2e-17 63.6 0.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KLO09517.1 - 3.9e-05 23.4 15.3 8.6e-05 22.3 10.6 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Matrilin_ccoil PF10393.4 KLO09517.1 - 0.013 14.8 1.7 0.031 13.6 0.6 2.1 2 0 0 2 2 2 0 Trimeric coiled-coil oligomerisation domain of matrilin UQ_con PF00179.21 KLO09518.1 - 4.3e-48 162.3 0.0 5.2e-48 162.0 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 KLO09518.1 - 7.4e-06 25.7 0.0 9.4e-06 25.4 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.8 KLO09518.1 - 0.014 15.0 0.1 0.026 14.2 0.0 1.5 1 1 0 1 1 1 0 UEV domain RWD PF05773.17 KLO09518.1 - 0.032 14.1 0.1 0.04 13.8 0.0 1.4 1 1 0 1 1 1 0 RWD domain zf-RING_2 PF13639.1 KLO09520.1 - 6.1e-14 51.5 13.1 9.1e-14 51.0 9.1 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 KLO09520.1 - 4.1e-09 36.3 11.9 6.7e-09 35.6 8.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KLO09520.1 - 4.7e-08 32.5 8.7 7.9e-08 31.8 6.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 KLO09520.1 - 4.8e-06 26.5 12.6 9.5e-06 25.6 8.7 1.5 1 1 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 KLO09520.1 - 6.4e-06 25.7 11.7 1.2e-05 24.8 8.1 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KLO09520.1 - 8e-06 25.4 9.5 1.2e-05 24.9 6.6 1.3 1 0 0 1 1 1 1 zinc-RING finger domain RINGv PF12906.2 KLO09520.1 - 0.0041 17.1 12.1 0.0073 16.3 8.4 1.5 1 0 0 1 1 1 1 RING-variant domain PHD PF00628.24 KLO09520.1 - 0.0059 16.2 12.4 0.015 15.0 8.7 1.7 1 1 0 1 1 1 1 PHD-finger zf-RING_UBOX PF13445.1 KLO09520.1 - 0.0089 15.7 3.4 0.0089 15.7 2.3 1.9 1 1 1 2 2 2 1 RING-type zinc-finger Prok-RING_1 PF14446.1 KLO09520.1 - 0.011 15.4 12.8 0.021 14.5 5.5 2.2 1 1 1 2 2 2 0 Prokaryotic RING finger family 1 zf-Apc11 PF12861.2 KLO09520.1 - 0.017 14.9 9.1 0.033 14.0 6.3 1.5 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.1 KLO09520.1 - 0.023 14.2 10.9 0.056 13.0 7.5 1.7 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain FANCL_C PF11793.3 KLO09520.1 - 0.045 13.7 11.9 0.2 11.6 8.2 1.9 1 1 0 1 1 1 0 FANCL C-terminal domain Rtf2 PF04641.7 KLO09520.1 - 0.58 9.3 3.6 1.8 7.6 2.4 1.8 1 1 1 2 2 2 0 Rtf2 RING-finger OrfB_Zn_ribbon PF07282.6 KLO09520.1 - 0.94 9.1 7.1 6 6.6 1.6 2.5 1 1 1 2 2 2 0 Putative transposase DNA-binding domain UPF0547 PF10571.4 KLO09520.1 - 2 8.2 9.7 3.5 7.4 0.9 3.3 3 0 0 3 3 3 0 Uncharacterised protein family UPF0547 zf-C3HC4_4 PF15227.1 KLO09520.1 - 8.4 6.3 11.9 47 3.9 8.2 2.2 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING Glyco_transf_6 PF03414.8 KLO09526.1 - 0.059 11.8 0.0 0.092 11.1 0.0 1.2 1 0 0 1 1 1 0 Glycosyltransferase family 6 CH PF00307.26 KLO09527.1 - 0.037 14.0 0.1 0.34 10.9 0.0 2.4 2 1 0 2 2 2 0 Calponin homology (CH) domain Epiglycanin_C PF14654.1 KLO09530.1 - 0.00023 21.0 0.2 0.00023 21.0 0.2 1.8 2 0 0 2 2 2 1 Mucin, catalytic, TM and cytoplasmic tail region DUF1049 PF06305.6 KLO09530.1 - 0.34 10.4 1.4 0.48 9.9 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1049) 3-HAO PF06052.7 KLO09533.1 - 5.8e-56 188.0 0.0 6.6e-56 187.9 0.0 1.0 1 0 0 1 1 1 1 3-hydroxyanthranilic acid dioxygenase Cupin_2 PF07883.6 KLO09533.1 - 8.2e-09 34.8 0.1 1.2e-08 34.3 0.0 1.3 1 0 0 1 1 1 1 Cupin domain Cupin_1 PF00190.17 KLO09533.1 - 0.00057 19.3 0.0 0.00085 18.7 0.0 1.3 1 0 0 1 1 1 1 Cupin AraC_binding PF02311.14 KLO09533.1 - 0.0009 18.9 0.0 0.0015 18.2 0.0 1.3 1 0 0 1 1 1 1 AraC-like ligand binding domain F-box-like PF12937.2 KLO09536.1 - 1.2e-07 31.3 0.3 6e-07 29.0 0.0 2.5 2 1 0 2 2 2 1 F-box-like PAP2 PF01569.16 KLO09542.1 - 6e-23 80.9 3.1 9.7e-23 80.2 2.2 1.4 1 1 0 1 1 1 1 PAP2 superfamily DUF2407_C PF13373.1 KLO09542.1 - 0.11 12.4 0.0 0.24 11.3 0.0 1.5 1 0 0 1 1 1 0 DUF2407 C-terminal domain CTD_bind PF04818.8 KLO09543.1 - 0.0095 16.1 0.0 0.021 15.0 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase II-binding domain. HSF_DNA-bind PF00447.12 KLO09545.1 - 6.1e-35 119.5 0.5 6.1e-35 119.5 0.3 1.7 2 0 0 2 2 2 1 HSF-type DNA-binding Actin PF00022.14 KLO09546.1 - 9.2e-117 389.7 0.0 5.5e-116 387.2 0.0 1.8 1 1 0 1 1 1 1 Actin MreB_Mbl PF06723.8 KLO09546.1 - 0.0023 16.5 0.0 0.011 14.3 0.0 2.0 2 1 0 2 2 2 1 MreB/Mbl protein Phos_pyr_kin PF08543.7 KLO09547.1 - 3.6e-10 39.4 0.0 5.6e-10 38.8 0.0 1.3 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase PfkB PF00294.19 KLO09547.1 - 1.5e-06 27.6 0.7 2.9e-05 23.3 0.0 2.3 3 0 0 3 3 3 2 pfkB family carbohydrate kinase START PF01852.14 KLO09548.1 - 7.9e-19 67.8 0.0 7e-11 41.8 0.0 3.7 4 0 0 4 4 4 3 START domain DUF787 PF05619.6 KLO09548.1 - 0.91 8.1 0.0 1.5 7.3 0.0 1.2 1 0 0 1 1 1 0 Borrelia burgdorferi protein of unknown function (DUF787) zf-BED PF02892.10 KLO09551.1 - 0.1 12.3 3.8 6.2 6.6 0.1 2.7 2 0 0 2 2 2 0 BED zinc finger DUF4451 PF14616.1 KLO09552.1 - 0.051 13.3 0.4 0.97 9.2 0.1 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4451) E6 PF00518.12 KLO09552.1 - 0.054 13.8 0.0 6.2 7.2 0.0 2.4 2 0 0 2 2 2 0 Early Protein (E6) zf-Sec23_Sec24 PF04810.10 KLO09552.1 - 0.1 12.1 0.9 2.7 7.6 0.1 2.4 2 0 0 2 2 2 0 Sec23/Sec24 zinc finger SH3_9 PF14604.1 KLO09554.1 - 4.5e-34 115.7 2.4 1.2e-17 63.2 0.1 2.4 2 0 0 2 2 2 2 Variant SH3 domain SH3_1 PF00018.23 KLO09554.1 - 1.4e-28 98.0 4.3 1.2e-14 53.3 0.3 2.4 2 0 0 2 2 2 2 SH3 domain SH3_2 PF07653.12 KLO09554.1 - 4.5e-21 74.0 0.2 5.7e-10 38.5 0.0 2.5 2 0 0 2 2 2 2 Variant SH3 domain Cofilin_ADF PF00241.15 KLO09554.1 - 1.6e-12 47.4 0.0 2.4e-12 46.8 0.0 1.3 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein MliC PF09864.4 KLO09554.1 - 0.03 14.0 0.3 0.073 12.8 0.0 1.8 2 0 0 2 2 2 0 Membrane-bound lysozyme-inhibitor of c-type lysozyme RNase_H2_suC PF08615.6 KLO09555.1 - 5e-22 78.2 0.0 6.6e-22 77.8 0.0 1.2 1 0 0 1 1 1 1 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) GPI-anchored PF10342.4 KLO09556.1 - 3.5e-09 37.0 0.9 3.5e-09 37.0 0.6 2.5 2 1 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family RYDR_ITPR PF01365.16 KLO09557.1 - 0.016 14.4 0.0 0.034 13.3 0.0 1.5 1 1 0 1 1 1 0 RIH domain DiS_P_DiS PF06750.8 KLO09558.1 - 0.14 11.9 0.1 0.62 9.8 0.1 1.9 2 0 0 2 2 2 0 Bacterial Peptidase A24 N-terminal domain zf-C3HC PF07967.8 KLO09559.1 - 0.047 13.4 0.4 7.9 6.2 0.0 2.5 2 1 0 2 2 2 0 C3HC zinc finger-like DUF2318 PF10080.4 KLO09559.1 - 0.1 12.3 0.1 3 7.6 0.0 2.6 3 0 0 3 3 3 0 Predicted membrane protein (DUF2318) F-box-like PF12937.2 KLO09560.1 - 0.74 9.5 5.0 2.6 7.8 1.2 2.8 2 0 0 2 2 2 0 F-box-like RNase_H PF00075.19 KLO09562.1 - 6.1e-08 33.0 0.0 8.3e-08 32.6 0.0 1.2 1 0 0 1 1 1 1 RNase H Rep_trans PF02486.14 KLO09564.1 - 0.11 11.9 0.0 0.15 11.5 0.0 1.3 1 0 0 1 1 1 0 Replication initiation factor Thioredoxin PF00085.15 KLO09566.1 - 3.4e-22 78.0 0.1 1.2e-21 76.3 0.1 1.9 2 0 0 2 2 2 1 Thioredoxin Thioredoxin_2 PF13098.1 KLO09566.1 - 0.0016 18.6 0.1 0.0064 16.6 0.1 2.0 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.1 KLO09566.1 - 0.011 15.7 0.7 2 8.5 0.0 3.2 2 1 0 3 3 3 0 Thioredoxin-like Thioredoxin_7 PF13899.1 KLO09566.1 - 0.023 14.7 0.1 0.065 13.2 0.1 1.7 1 0 0 1 1 1 0 Thioredoxin-like Thioredoxin_9 PF14595.1 KLO09566.1 - 0.089 12.3 0.1 0.23 11.0 0.0 1.6 1 0 0 1 1 1 0 Thioredoxin DUF3449 PF11931.3 KLO09567.1 - 0.11 11.9 0.0 0.22 11.0 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3449) zf-met PF12874.2 KLO09567.1 - 8.2 6.7 5.9 6.8 7.0 0.3 2.6 2 0 0 2 2 2 0 Zinc-finger of C2H2 type Zn_clus PF00172.13 KLO09568.1 - 1.1e-24 86.0 85.5 4.3e-07 29.7 9.1 5.7 5 1 1 6 6 6 5 Fungal Zn(2)-Cys(6) binuclear cluster domain Stc1 PF12898.2 KLO09569.1 - 0.57 10.2 7.1 0.71 9.9 0.2 3.0 2 1 1 3 3 3 0 Stc1 domain Glyco_hydro_16 PF00722.16 KLO09570.1 - 1.5e-09 37.3 0.7 1.8e-08 33.9 0.0 2.2 1 1 1 2 2 2 2 Glycosyl hydrolases family 16 SOBP PF15279.1 KLO09571.1 - 0.42 10.9 5.3 0.54 10.5 3.7 1.2 1 0 0 1 1 1 0 Sine oculis-binding protein RVP_2 PF08284.6 KLO09574.1 - 0.0036 17.2 0.0 0.0044 16.9 0.0 1.1 1 0 0 1 1 1 1 Retroviral aspartyl protease zf-CCHC PF00098.18 KLO09575.1 - 0.00014 21.5 3.1 0.00021 21.0 2.1 1.3 1 0 0 1 1 1 1 Zinc knuckle Retrotrans_gag PF03732.12 KLO09575.1 - 0.021 14.8 0.1 0.057 13.4 0.1 1.7 1 0 0 1 1 1 0 Retrotransposon gag protein zf-CCHC_3 PF13917.1 KLO09575.1 - 0.052 13.2 0.8 0.095 12.4 0.6 1.4 1 0 0 1 1 1 0 Zinc knuckle DUF4055 PF13264.1 KLO09575.1 - 0.099 12.7 0.0 0.23 11.5 0.0 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4055) DUF605 PF04652.11 KLO09575.1 - 9.2 5.5 15.9 13 5.0 11.0 1.2 1 0 0 1 1 1 0 Vta1 like HTH_29 PF13551.1 KLO09578.1 - 1.3e-13 51.0 0.1 1.5e-13 50.8 0.0 1.1 1 0 0 1 1 1 1 Winged helix-turn helix HTH_32 PF13565.1 KLO09578.1 - 7e-10 39.5 0.1 9.6e-10 39.1 0.1 1.2 1 0 0 1 1 1 1 Homeodomain-like domain HTH_23 PF13384.1 KLO09578.1 - 6.1e-08 32.0 0.1 5.2e-06 25.9 0.0 2.2 2 0 0 2 2 2 1 Homeodomain-like domain HTH_7 PF02796.10 KLO09578.1 - 5.6e-05 22.9 0.0 0.00037 20.3 0.0 2.2 3 0 0 3 3 3 1 Helix-turn-helix domain of resolvase HTH_28 PF13518.1 KLO09578.1 - 0.00046 20.1 0.4 0.0015 18.5 0.0 1.9 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_Tnp_Tc3_2 PF01498.13 KLO09578.1 - 0.0014 18.6 0.2 0.0077 16.2 0.0 1.9 2 0 0 2 2 2 1 Transposase TrmB PF01978.14 KLO09578.1 - 0.0021 17.7 0.0 0.0061 16.2 0.0 1.7 2 0 0 2 2 2 1 Sugar-specific transcriptional regulator TrmB HTH_33 PF13592.1 KLO09578.1 - 0.0049 16.3 0.0 0.011 15.3 0.0 1.5 1 0 0 1 1 1 1 Winged helix-turn helix Sigma70_r4_2 PF08281.7 KLO09578.1 - 0.0074 15.7 0.0 0.095 12.1 0.0 2.2 2 0 0 2 2 2 1 Sigma-70, region 4 HTH_11 PF08279.7 KLO09578.1 - 0.011 15.3 0.0 6 6.6 0.0 2.3 2 0 0 2 2 2 0 HTH domain HTH_Tnp_IS630 PF01710.11 KLO09578.1 - 0.011 15.4 0.0 0.019 14.6 0.0 1.4 1 1 0 1 1 1 0 Transposase HTH_17 PF12728.2 KLO09578.1 - 0.012 15.8 0.4 0.39 11.0 0.0 2.2 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_IclR PF09339.5 KLO09578.1 - 0.019 14.5 0.0 0.046 13.3 0.0 1.7 1 0 0 1 1 1 0 IclR helix-turn-helix domain HTH_36 PF13730.1 KLO09578.1 - 0.15 12.2 0.0 0.38 10.9 0.0 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain CTP-dep_RFKase PF01982.11 KLO09579.1 - 0.064 12.8 0.0 0.17 11.4 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function DUF120 AT_hook PF02178.14 KLO09579.1 - 0.12 12.1 6.8 0.69 9.7 4.7 2.5 1 0 0 1 1 1 0 AT hook motif CorA PF01544.13 KLO09580.1 - 0.037 13.0 1.7 0.64 8.9 0.1 2.4 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein Astacin PF01400.19 KLO09581.1 - 7.5e-09 35.2 1.8 8.3e-08 31.8 1.2 2.2 1 1 0 1 1 1 1 Astacin (Peptidase family M12A) Reprolysin_2 PF13574.1 KLO09581.1 - 4.1e-06 26.9 0.1 6.3e-06 26.3 0.1 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.1 KLO09581.1 - 0.00011 22.2 0.4 0.00016 21.6 0.3 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12 Peptidase_M10 PF00413.19 KLO09581.1 - 0.00041 20.0 3.3 0.0033 17.1 1.4 2.4 2 1 0 2 2 2 1 Matrixin Reprolysin_3 PF13582.1 KLO09581.1 - 0.0012 19.3 0.0 0.0023 18.4 0.0 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.1 KLO09581.1 - 0.0048 16.4 2.0 0.009 15.5 1.4 1.6 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like DUF3152 PF11350.3 KLO09581.1 - 0.012 15.0 0.5 0.069 12.6 0.3 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF3152) Reprolysin PF01421.14 KLO09581.1 - 0.021 14.4 0.0 0.04 13.5 0.0 1.4 1 1 0 1 1 1 0 Reprolysin (M12B) family zinc metalloprotease Peptidase_M66 PF10462.4 KLO09581.1 - 0.058 12.2 1.2 0.13 11.0 0.5 1.8 1 1 1 2 2 2 0 Peptidase M66 Peptidase_M57 PF12388.3 KLO09581.1 - 0.074 12.3 0.0 0.12 11.7 0.0 1.4 1 0 0 1 1 1 0 Dual-action HEIGH metallo-peptidase DUF1025 PF06262.6 KLO09581.1 - 0.12 12.1 0.1 0.26 11.0 0.1 1.5 1 0 0 1 1 1 0 Possibl zinc metallo-peptidase YbjM PF11045.3 KLO09582.1 - 0.033 13.9 1.6 0.35 10.6 1.3 2.3 2 1 0 2 2 2 0 Putative inner membrane protein of Enterobacteriaceae DUF3176 PF11374.3 KLO09583.1 - 1.5 8.7 8.5 1.9 8.3 0.8 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3176) Hydrophobin PF01185.13 KLO09584.1 - 8.5e-23 80.6 8.6 9.4e-23 80.4 5.9 1.0 1 0 0 1 1 1 1 Fungal hydrophobin Hydrophobin PF01185.13 KLO09586.1 - 2.3e-22 79.2 9.4 2.9e-22 78.9 6.5 1.1 1 0 0 1 1 1 1 Fungal hydrophobin DUF1180 PF06679.7 KLO09586.1 - 0.073 12.9 0.1 0.094 12.6 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) Hydrophobin PF01185.13 KLO09587.1 - 1e-21 77.1 9.5 1.3e-21 76.7 6.6 1.2 1 0 0 1 1 1 1 Fungal hydrophobin DUF2673 PF10880.3 KLO09587.1 - 0.4 10.7 2.1 0.39 10.7 0.9 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2673) ApoL PF05461.6 KLO09587.1 - 0.73 9.0 2.2 1 8.5 1.5 1.1 1 0 0 1 1 1 0 Apolipoprotein L FAM24 PF15193.1 KLO09587.1 - 4.2 7.6 6.1 0.3 11.3 0.5 1.8 2 0 0 2 2 2 0 FAM24 family Hydrophobin PF01185.13 KLO09588.1 - 7.9e-08 32.6 2.1 2.7e-07 30.9 1.4 1.8 1 1 0 1 1 1 1 Fungal hydrophobin Hydrophobin PF01185.13 KLO09589.1 - 1.6e-11 44.4 3.2 2.1e-11 44.1 2.2 1.1 1 0 0 1 1 1 1 Fungal hydrophobin Hydrophobin PF01185.13 KLO09590.1 - 4.3e-18 65.5 8.1 6.8e-18 64.9 5.6 1.3 1 0 0 1 1 1 1 Fungal hydrophobin DPBB_1 PF03330.13 KLO09596.1 - 6.6e-09 35.6 0.0 1e-08 35.0 0.0 1.3 1 1 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Barwin PF00967.12 KLO09596.1 - 0.0022 17.6 0.0 0.0027 17.3 0.0 1.2 1 0 0 1 1 1 1 Barwin family F-box-like PF12937.2 KLO09599.1 - 0.00039 20.0 0.0 0.0018 17.9 0.0 2.2 1 1 0 1 1 1 1 F-box-like DUF3778 PF12620.3 KLO09599.1 - 0.063 12.8 0.2 0.2 11.2 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3778) F-box PF00646.28 KLO09599.1 - 0.086 12.5 7.3 1.1 8.9 0.1 3.3 4 0 0 4 4 4 0 F-box domain WD40 PF00400.27 KLO09600.1 - 5.3e-55 181.4 17.7 1.3e-08 34.4 0.0 7.4 7 0 0 7 7 7 7 WD domain, G-beta repeat Nucleoporin_N PF08801.6 KLO09600.1 - 0.0061 15.3 0.0 1.2 7.7 0.0 2.4 1 1 1 2 2 2 2 Nup133 N terminal like Nup160 PF11715.3 KLO09600.1 - 0.07 11.2 4.3 1.5 6.9 0.1 3.4 1 1 3 4 4 4 0 Nucleoporin Nup120/160 Hydrophobin PF01185.13 KLO09601.1 - 2.2e-07 31.2 7.8 2.9e-07 30.8 5.4 1.2 1 0 0 1 1 1 1 Fungal hydrophobin DUF1180 PF06679.7 KLO09601.1 - 0.37 10.6 2.4 0.46 10.3 1.6 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1180) DIM1 PF02966.11 KLO09602.1 - 1.2e-67 225.4 0.4 1.4e-67 225.2 0.3 1.0 1 0 0 1 1 1 1 Mitosis protein DIM1 Thioredoxin PF00085.15 KLO09602.1 - 0.00017 21.1 0.1 0.00023 20.8 0.1 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.1 KLO09602.1 - 0.013 15.5 0.7 0.022 14.8 0.3 1.3 1 1 0 1 1 1 0 Thioredoxin-like Thioredoxin_7 PF13899.1 KLO09602.1 - 0.063 13.3 0.0 0.13 12.2 0.0 1.5 2 0 0 2 2 2 0 Thioredoxin-like Thioredox_DsbH PF03190.10 KLO09602.1 - 0.24 11.1 1.4 0.29 10.8 0.5 1.4 1 1 0 1 1 1 0 Protein of unknown function, DUF255 DUF2470 PF10615.4 KLO09603.1 - 4.2e-15 55.7 0.0 7.6e-15 54.9 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2470) DUF4499 PF14934.1 KLO09603.1 - 1.3e-11 44.2 0.5 2.5e-11 43.3 0.4 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4499) GAT PF03127.9 KLO09604.1 - 2.7e-05 24.0 0.4 3.8e-05 23.5 0.3 1.2 1 0 0 1 1 1 1 GAT domain DUF3316 PF11777.3 KLO09604.1 - 0.036 13.8 0.4 0.056 13.2 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3316) FliJ PF02050.11 KLO09604.1 - 0.35 10.9 8.9 0.46 10.5 6.2 1.2 1 0 0 1 1 1 0 Flagellar FliJ protein DUF4413 PF14372.1 KLO09608.1 - 0.00097 19.0 2.0 0.0013 18.6 1.4 1.3 1 1 0 1 1 1 1 Domain of unknown function (DUF4413) DNA_topoisoIV PF00521.15 KLO09608.1 - 0.02 13.7 0.2 0.022 13.6 0.1 1.0 1 0 0 1 1 1 0 DNA gyrase/topoisomerase IV, subunit A Phtf-FEM1B_bdg PF12129.3 KLO09609.1 - 0.15 11.3 0.7 0.27 10.5 0.5 1.3 1 0 0 1 1 1 0 Male germ-cell putative homeodomain transcription factor Mito_carr PF00153.22 KLO09610.1 - 1.7e-18 66.1 1.1 3.1e-10 39.6 0.1 2.3 2 0 0 2 2 2 2 Mitochondrial carrier protein Jiraiya PF15038.1 KLO09613.1 - 0.055 12.8 0.4 0.078 12.3 0.3 1.2 1 0 0 1 1 1 0 Jiraiya Pkinase_Tyr PF07714.12 KLO09613.1 - 0.09 11.8 0.0 0.11 11.4 0.0 1.2 1 0 0 1 1 1 0 Protein tyrosine kinase BTB PF00651.26 KLO09614.1 - 0.00013 21.9 0.0 0.00029 20.8 0.0 1.6 1 1 0 1 1 1 1 BTB/POZ domain UPF0054 PF02130.12 KLO09614.1 - 0.062 12.5 0.2 0.13 11.5 0.1 1.5 1 0 0 1 1 1 0 Uncharacterized protein family UPF0054 SSrecog PF03531.9 KLO09618.1 - 0.006 15.9 0.0 1 8.6 0.0 2.2 2 0 0 2 2 2 2 Structure-specific recognition protein (SSRP1) NmrA PF05368.8 KLO09619.1 - 1.5e-18 66.8 0.0 2.6e-18 66.1 0.0 1.3 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 KLO09619.1 - 2.5e-05 24.3 0.1 4.5e-05 23.5 0.0 1.5 1 1 0 1 1 1 1 NADH(P)-binding DapB_N PF01113.15 KLO09619.1 - 4.2e-05 23.4 0.1 9.8e-05 22.2 0.1 1.7 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus Saccharop_dh PF03435.13 KLO09619.1 - 0.00026 20.1 0.1 0.00043 19.3 0.1 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase Semialdhyde_dh PF01118.19 KLO09619.1 - 0.0012 19.1 0.1 0.0021 18.3 0.1 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain 3Beta_HSD PF01073.14 KLO09619.1 - 0.041 12.5 0.2 0.062 11.9 0.1 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.20 KLO09619.1 - 0.053 13.4 0.1 0.097 12.5 0.0 1.4 1 0 0 1 1 1 0 short chain dehydrogenase Ldh_1_N PF00056.18 KLO09619.1 - 0.092 12.5 0.1 0.16 11.7 0.0 1.4 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain BTB PF00651.26 KLO09620.1 - 0.0055 16.6 0.3 0.016 15.1 0.0 1.9 2 0 0 2 2 2 1 BTB/POZ domain Prok-RING_1 PF14446.1 KLO09620.1 - 0.034 13.8 2.1 0.057 13.1 1.5 1.3 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 zf-MYND PF01753.13 KLO09620.1 - 0.17 11.7 1.8 0.29 11.0 1.2 1.4 1 0 0 1 1 1 0 MYND finger BTB PF00651.26 KLO09621.1 - 6.3e-13 48.6 0.0 8.1e-06 25.8 0.0 2.5 2 0 0 2 2 2 2 BTB/POZ domain FYVE_2 PF02318.11 KLO09621.1 - 2e-05 24.4 1.2 0.0019 18.0 0.4 2.3 2 0 0 2 2 2 1 FYVE-type zinc finger Rad50_zn_hook PF04423.9 KLO09621.1 - 0.079 12.4 0.3 0.35 10.3 0.2 2.1 1 0 0 1 1 1 0 Rad50 zinc hook motif PTS-HPr PF00381.14 KLO09621.1 - 0.17 11.8 0.1 0.49 10.3 0.1 1.7 1 0 0 1 1 1 0 PTS HPr component phosphorylation site IBR PF01485.16 KLO09621.1 - 0.18 11.7 9.3 2.6 7.9 0.2 2.4 2 0 0 2 2 2 0 IBR domain FYVE PF01363.16 KLO09621.1 - 0.28 11.1 8.2 0.79 9.6 1.4 2.7 2 1 0 2 2 2 0 FYVE zinc finger DZR PF12773.2 KLO09621.1 - 4.3 7.2 13.1 0.55 10.1 0.4 2.4 2 0 0 2 2 2 0 Double zinc ribbon BTB PF00651.26 KLO09622.1 - 2.8e-05 24.0 0.0 5.5e-05 23.1 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain OrfB_Zn_ribbon PF07282.6 KLO09622.1 - 0.012 15.2 0.2 0.023 14.3 0.2 1.5 1 0 0 1 1 1 0 Putative transposase DNA-binding domain zf-C2H2 PF00096.21 KLO09622.1 - 0.96 9.9 2.9 1.3 9.5 0.1 2.3 2 0 0 2 2 2 0 Zinc finger, C2H2 type BTB PF00651.26 KLO09623.1 - 6.2e-09 35.8 0.0 8.1e-09 35.4 0.0 1.2 1 0 0 1 1 1 1 BTB/POZ domain Ndufs5 PF10200.4 KLO09623.1 - 0.086 12.8 0.0 0.13 12.2 0.0 1.2 1 0 0 1 1 1 0 NADH:ubiquinone oxidoreductase, NDUFS5-15kDa DUF3209 PF11483.3 KLO09623.1 - 0.13 12.6 0.0 0.19 12.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3209) BTB PF00651.26 KLO09625.1 - 4.1e-05 23.5 0.0 8.4e-05 22.5 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain BTB PF00651.26 KLO09626.1 - 7.6e-07 29.1 0.0 1.3e-06 28.3 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain OrfB_Zn_ribbon PF07282.6 KLO09626.1 - 0.37 10.4 2.1 0.65 9.6 0.2 2.0 1 1 1 2 2 2 0 Putative transposase DNA-binding domain BTB PF00651.26 KLO09627.1 - 8.5e-07 28.9 0.0 1.5e-06 28.1 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain zf-NADH-PPase PF09297.6 KLO09627.1 - 0.0013 18.1 0.9 0.023 14.1 0.1 2.4 2 0 0 2 2 2 1 NADH pyrophosphatase zinc ribbon domain Ogr_Delta PF04606.7 KLO09627.1 - 0.08 12.6 0.5 5.3 6.7 0.1 2.5 2 0 0 2 2 2 0 Ogr/Delta-like zinc finger Mut7-C PF01927.11 KLO09627.1 - 0.086 12.8 0.3 0.16 11.9 0.2 1.4 1 0 0 1 1 1 0 Mut7-C RNAse domain Lar_restr_allev PF14354.1 KLO09627.1 - 0.091 13.0 0.2 0.21 11.9 0.2 1.6 1 0 0 1 1 1 0 Restriction alleviation protein Lar Zn-ribbon_8 PF09723.5 KLO09627.1 - 0.11 12.4 0.4 1.2 9.0 0.0 2.4 2 0 0 2 2 2 0 Zinc ribbon domain Zn_Tnp_IS1595 PF12760.2 KLO09627.1 - 0.39 10.5 2.3 1.4 8.8 1.6 1.9 1 1 0 1 1 1 0 Transposase zinc-ribbon domain F-box-like PF12937.2 KLO09629.1 - 5.3e-08 32.4 0.7 1.4e-07 31.0 0.5 1.8 1 0 0 1 1 1 1 F-box-like F-box-like PF12937.2 KLO09630.1 - 1.7e-07 30.8 0.9 1.7e-07 30.8 0.6 2.1 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 KLO09630.1 - 0.075 12.7 1.9 0.5 10.0 1.4 2.4 1 1 0 1 1 1 0 F-box domain F-box-like PF12937.2 KLO09631.1 - 7.6e-08 31.9 1.8 7.6e-08 31.9 1.2 2.8 3 0 0 3 3 3 1 F-box-like F-box-like PF12937.2 KLO09632.1 - 0.00079 19.1 0.0 0.0028 17.3 0.0 2.0 1 0 0 1 1 1 1 F-box-like F-box-like PF12937.2 KLO09633.1 - 2.6e-08 33.4 1.3 5.2e-08 32.4 0.1 2.3 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 KLO09633.1 - 0.024 14.2 2.7 0.3 10.8 0.9 3.5 3 1 1 4 4 4 0 F-box domain F-box-like PF12937.2 KLO09634.1 - 8.3e-09 35.0 0.2 5.1e-08 32.5 0.1 2.4 2 0 0 2 2 2 1 F-box-like DUF3310 PF11753.3 KLO09634.1 - 0.11 12.4 0.0 0.28 11.1 0.0 1.6 1 0 0 1 1 1 0 Protein of unknwon function (DUF3310) F-box PF00646.28 KLO09634.1 - 0.19 11.4 3.0 0.72 9.5 0.5 3.0 2 1 0 2 2 2 0 F-box domain F-box-like PF12937.2 KLO09635.1 - 2.7e-09 36.5 0.1 9.9e-09 34.7 0.1 2.1 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KLO09635.1 - 0.13 11.9 2.4 14 5.4 0.1 3.2 3 0 0 3 3 3 0 F-box domain F-box-like PF12937.2 KLO09636.1 - 5.3e-09 35.6 0.1 1.3e-08 34.3 0.1 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KLO09636.1 - 0.016 14.8 0.3 0.066 12.8 0.2 2.0 1 1 0 1 1 1 0 F-box domain F-box-like PF12937.2 KLO09637.1 - 8.1e-08 31.8 0.3 2.1e-07 30.5 0.2 1.8 1 0 0 1 1 1 1 F-box-like F-box-like PF12937.2 KLO09638.1 - 2.3e-07 30.4 0.7 9.9e-07 28.3 0.5 2.2 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KLO09638.1 - 0.18 11.5 5.9 0.08 12.6 0.7 3.0 3 0 0 3 3 3 0 F-box domain F-box-like PF12937.2 KLO09639.1 - 6.1e-09 35.4 0.2 1.9e-08 33.8 0.1 2.0 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KLO09639.1 - 0.051 13.2 0.2 0.18 11.5 0.1 2.0 1 0 0 1 1 1 0 F-box domain LRR19-TM PF15176.1 KLO09640.1 - 1.7 8.3 5.0 0.55 9.9 0.5 2.1 2 0 0 2 2 2 0 Leucine-rich repeat family 19 TM domain zf-C2H2 PF00096.21 KLO09641.1 - 2.2e-13 49.6 12.6 4.3e-07 29.8 3.5 2.1 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 KLO09641.1 - 3.4e-11 42.8 14.3 1.3e-07 31.5 0.1 3.0 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 KLO09641.1 - 1.8e-10 40.3 10.9 4.4e-05 23.5 0.4 2.1 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 KLO09641.1 - 9.7e-07 28.7 4.1 1.4e-05 25.0 0.4 2.2 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2HC_2 PF13913.1 KLO09641.1 - 3.3e-05 23.4 12.0 0.0031 17.1 2.3 2.7 2 1 0 2 2 2 2 zinc-finger of a C2HC-type zf-met PF12874.2 KLO09641.1 - 6.6e-05 22.9 4.4 0.00014 21.9 0.5 2.3 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.1 KLO09641.1 - 0.0018 18.1 0.8 0.0018 18.1 0.6 2.4 3 0 0 3 3 2 1 C2H2-type zinc finger zf-Di19 PF05605.7 KLO09641.1 - 0.002 18.2 4.3 0.032 14.3 3.0 2.0 1 1 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding zinc_ribbon_5 PF13719.1 KLO09641.1 - 0.0053 16.3 1.0 0.13 11.8 0.1 2.3 2 1 0 2 2 2 1 zinc-ribbon domain zinc_ribbon_4 PF13717.1 KLO09641.1 - 0.0056 16.3 1.1 0.12 12.0 0.1 2.3 2 1 0 2 2 2 1 zinc-ribbon domain zf-C2H2_2 PF12756.2 KLO09641.1 - 0.014 15.4 2.8 0.072 13.2 0.4 2.0 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-CHCC PF10276.4 KLO09641.1 - 0.023 14.5 1.3 1.8 8.4 0.0 2.1 2 0 0 2 2 2 0 Zinc-finger domain Zn-ribbon_8 PF09723.5 KLO09641.1 - 0.041 13.8 3.2 4.5 7.3 0.1 2.2 2 0 0 2 2 2 0 Zinc ribbon domain Ogr_Delta PF04606.7 KLO09641.1 - 0.049 13.2 2.0 0.071 12.7 1.4 1.3 1 0 0 1 1 1 0 Ogr/Delta-like zinc finger CpXC PF14353.1 KLO09641.1 - 0.06 13.3 1.5 0.65 9.9 1.0 2.0 1 1 0 1 1 1 0 CpXC protein zf-HYPF PF07503.7 KLO09641.1 - 0.11 11.9 5.3 0.39 10.1 0.2 2.2 2 0 0 2 2 2 0 HypF finger ATPase-cat_bd PF12156.3 KLO09641.1 - 0.16 12.5 1.3 0.18 12.3 0.9 1.2 1 0 0 1 1 1 0 Putative metal-binding domain of cation transport ATPase zf-UBP PF02148.14 KLO09641.1 - 0.24 11.5 1.6 0.68 10.0 1.1 1.8 1 1 0 1 1 1 0 Zn-finger in ubiquitin-hydrolases and other protein zf-ribbon_3 PF13248.1 KLO09641.1 - 0.32 10.2 3.0 1.5 8.1 0.0 2.5 3 0 0 3 3 3 0 zinc-ribbon domain IBR PF01485.16 KLO09641.1 - 0.32 10.9 3.3 1.4 8.8 0.0 2.1 1 1 1 2 2 2 0 IBR domain ADK_lid PF05191.9 KLO09641.1 - 0.38 10.4 3.5 6.8 6.4 0.1 2.2 2 0 0 2 2 2 0 Adenylate kinase, active site lid zf-BED PF02892.10 KLO09641.1 - 0.41 10.4 8.2 1.7 8.5 2.1 2.2 1 1 1 2 2 2 0 BED zinc finger zf-Mss51 PF13824.1 KLO09641.1 - 0.64 9.9 3.3 0.92 9.4 2.3 1.4 1 1 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 Cys_rich_CPXG PF14255.1 KLO09641.1 - 0.72 9.7 3.9 10 6.0 0.5 2.5 2 1 1 3 3 3 0 Cysteine-rich CPXCG zf-H2C2_5 PF13909.1 KLO09641.1 - 0.74 10.1 13.2 1.2 9.4 2.5 2.8 2 2 0 2 2 2 0 C2H2-type zinc-finger domain FYVE PF01363.16 KLO09641.1 - 0.88 9.5 4.5 43 4.1 3.1 2.1 1 1 0 1 1 1 0 FYVE zinc finger Zn_Tnp_IS1595 PF12760.2 KLO09641.1 - 1.1 9.1 6.4 2.1 8.2 3.9 1.8 1 1 1 2 2 2 0 Transposase zinc-ribbon domain zf-ISL3 PF14690.1 KLO09641.1 - 3.5 7.7 7.3 1 9.4 0.3 2.4 2 1 0 2 2 2 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 zinc_ribbon_2 PF13240.1 KLO09641.1 - 5.6 6.5 7.6 3 7.4 1.0 2.7 3 0 0 3 3 3 0 zinc-ribbon domain DUF605 PF04652.11 KLO09644.1 - 0.98 8.7 12.5 1.2 8.5 8.7 1.1 1 0 0 1 1 1 0 Vta1 like Totivirus_coat PF05518.6 KLO09644.1 - 3 5.5 8.1 3.1 5.5 5.6 1.1 1 0 0 1 1 1 0 Totivirus coat protein Helicase_C PF00271.26 KLO09646.1 - 3.4e-15 55.6 0.0 9.9e-15 54.1 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 KLO09646.1 - 2.6e-12 46.5 0.1 1.3e-11 44.2 0.0 2.1 3 0 0 3 3 3 1 DEAD/DEAH box helicase ResIII PF04851.10 KLO09646.1 - 3.7e-05 23.6 0.3 0.0011 18.8 0.0 2.9 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit SNF2_N PF00176.18 KLO09646.1 - 0.0044 15.8 0.0 0.013 14.2 0.0 1.8 2 0 0 2 2 2 1 SNF2 family N-terminal domain DUF687 PF05095.7 KLO09646.1 - 0.012 14.0 0.0 0.056 11.8 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF687) OmpH PF03938.9 KLO09646.1 - 0.11 12.4 12.3 0.21 11.4 8.5 1.4 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) DDHD PF02862.12 KLO09646.1 - 1.3 8.7 3.7 2.4 7.9 2.5 1.3 1 0 0 1 1 1 0 DDHD domain Radial_spoke_3 PF06098.6 KLO09646.1 - 6.7 5.6 17.7 13 4.6 12.3 1.4 1 0 0 1 1 1 0 Radial spoke protein 3 Rho_N PF07498.7 KLO09647.1 - 0.00035 20.2 0.7 0.0066 16.1 0.1 2.5 2 0 0 2 2 2 1 Rho termination factor, N-terminal domain BTB PF00651.26 KLO09648.1 - 0.00069 19.5 0.0 0.0017 18.3 0.0 1.6 1 0 0 1 1 1 1 BTB/POZ domain DUF3695 PF12494.3 KLO09649.1 - 0.061 13.0 2.5 0.088 12.5 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3695) DUF373 PF04123.8 KLO09653.1 - 0.024 13.6 1.2 0.75 8.7 0.3 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF373) DUF4022 PF13214.1 KLO09653.1 - 0.12 12.4 2.0 0.16 12.0 0.2 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF4022) Copine PF07002.11 KLO09655.1 - 0.036 13.8 0.1 0.064 13.0 0.0 1.4 2 0 0 2 2 2 0 Copine Trp_oprn_chp PF09534.5 KLO09656.1 - 0.42 10.2 4.4 3 7.3 1.9 2.1 2 0 0 2 2 2 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) NACHT PF05729.7 KLO09665.1 - 3.2e-10 39.9 0.0 9.4e-10 38.3 0.0 1.7 1 1 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 KLO09665.1 - 1.2e-05 25.3 0.1 5.2e-05 23.3 0.0 2.0 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 KLO09665.1 - 0.012 15.7 0.0 0.031 14.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.17 KLO09665.1 - 0.017 14.0 0.0 0.026 13.3 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain AAA_25 PF13481.1 KLO09665.1 - 0.032 13.6 0.1 0.099 12.0 0.0 1.8 1 1 0 1 1 1 0 AAA domain AAA PF00004.24 KLO09665.1 - 0.039 14.1 0.0 0.093 12.9 0.0 1.7 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) APS_kinase PF01583.15 KLO09665.1 - 0.1 12.2 0.0 0.17 11.5 0.0 1.3 1 0 0 1 1 1 0 Adenylylsulphate kinase tRNA-synt_1g PF09334.6 KLO09666.1 - 5.8e-92 308.3 0.0 1.2e-91 307.2 0.0 1.5 1 1 0 1 1 1 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.17 KLO09666.1 - 1.9e-22 79.0 0.2 8.1e-10 37.3 0.0 3.2 2 1 2 4 4 4 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1e PF01406.14 KLO09666.1 - 5.8e-11 42.0 0.0 6.7e-05 22.1 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain tRNA-synt_1f PF01921.13 KLO09666.1 - 0.00013 20.7 0.0 0.11 11.0 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetases class I (K) AMP-binding PF00501.23 KLO09667.1 - 3.9e-15 55.1 0.2 6e-15 54.5 0.1 1.3 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 KLO09667.1 - 2.3e-11 44.4 0.5 3.5e-11 43.8 0.4 1.3 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain MukE PF04288.8 KLO09667.1 - 0.095 11.4 0.0 0.28 9.9 0.0 1.7 2 0 0 2 2 2 0 MukE-like family RTX_C PF08339.5 KLO09667.1 - 0.098 12.3 0.2 0.16 11.6 0.0 1.6 2 0 0 2 2 2 0 RTX C-terminal domain Abhydrolase_3 PF07859.8 KLO09669.1 - 1.2e-15 57.6 0.0 3.7e-14 52.7 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KLO09669.1 - 1.2e-08 34.8 0.0 1.6e-08 34.3 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family COesterase PF00135.23 KLO09669.1 - 1.9e-07 30.1 0.0 5.1e-07 28.7 0.0 1.6 1 1 0 1 1 1 1 Carboxylesterase family DUF2424 PF10340.4 KLO09669.1 - 3.6e-07 29.1 0.0 4.8e-07 28.7 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2424) Peptidase_S9 PF00326.16 KLO09669.1 - 5e-07 29.1 0.0 0.014 14.5 0.0 2.6 3 0 0 3 3 3 2 Prolyl oligopeptidase family Abhydrolase_6 PF12697.2 KLO09669.1 - 4.1e-06 26.8 0.0 6.9e-06 26.1 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Lipase_3 PF01764.20 KLO09669.1 - 0.013 15.0 0.0 0.021 14.4 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) Abhydrolase_1 PF00561.15 KLO09669.1 - 0.027 14.0 0.0 0.065 12.7 0.0 1.6 2 0 0 2 2 2 0 alpha/beta hydrolase fold DUF2974 PF11187.3 KLO09669.1 - 0.085 12.2 0.0 0.13 11.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) PGAP1 PF07819.8 KLO09669.1 - 0.12 11.8 0.0 0.18 11.3 0.0 1.2 1 0 0 1 1 1 0 PGAP1-like protein DUF900 PF05990.7 KLO09669.1 - 0.18 11.1 0.0 0.26 10.5 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) Fungal_trans PF04082.13 KLO09670.1 - 9.6e-13 47.6 0.1 1.7e-12 46.7 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KLO09670.1 - 0.00024 20.9 11.9 0.0005 19.9 8.2 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 KLO09671.1 - 3.1e-15 55.7 0.1 7.6e-15 54.4 0.0 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KLO09671.1 - 3.4e-05 23.6 13.1 5.8e-05 22.9 9.1 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 KLO09672.1 - 1.5e-18 66.5 0.0 3.5e-18 65.4 0.0 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KLO09672.1 - 1.4e-05 24.8 11.8 2.5e-05 24.0 8.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF3529 PF12046.3 KLO09673.1 - 3.7 6.5 6.4 11 4.9 0.2 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF3529) FF PF01846.14 KLO09674.1 - 1e-38 130.9 17.0 8.7e-12 44.8 0.0 5.8 6 0 0 6 6 6 5 FF domain WW PF00397.21 KLO09674.1 - 1.3e-08 34.4 14.6 9e-07 28.6 0.1 3.2 3 0 0 3 3 3 2 WW domain DDHD PF02862.12 KLO09674.1 - 5 6.8 26.9 0.026 14.3 7.3 2.7 2 1 0 2 2 2 0 DDHD domain Ycf1 PF05758.7 KLO09674.1 - 9.3 3.8 15.6 1.2 6.7 6.6 2.2 2 0 0 2 2 2 0 Ycf1 Fungal_trans PF04082.13 KLO09675.1 - 6.1e-20 71.1 0.3 1.2e-19 70.2 0.2 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KLO09675.1 - 0.00015 21.5 15.3 0.00035 20.4 10.6 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 KLO09676.1 - 1.2e-19 70.1 0.1 2.8e-19 69.0 0.1 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KLO09676.1 - 0.0015 18.3 16.7 0.0026 17.6 11.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Matrilin_ccoil PF10393.4 KLO09676.1 - 0.049 13.0 0.6 0.09 12.1 0.4 1.4 1 0 0 1 1 1 0 Trimeric coiled-coil oligomerisation domain of matrilin DUF3827 PF12877.2 KLO09676.1 - 0.11 10.5 0.3 0.18 9.8 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) F-box-like PF12937.2 KLO09677.1 - 5.5e-06 26.0 0.1 1.4e-05 24.7 0.0 1.7 1 0 0 1 1 1 1 F-box-like Fungal_trans PF04082.13 KLO09678.1 - 2.3e-13 49.6 0.0 5.5e-13 48.3 0.0 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KLO09678.1 - 0.00016 21.5 12.6 0.00028 20.7 8.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Matrilin_ccoil PF10393.4 KLO09678.1 - 0.013 14.8 0.5 0.028 13.7 0.3 1.5 1 0 0 1 1 1 0 Trimeric coiled-coil oligomerisation domain of matrilin AKAP2_C PF15304.1 KLO09678.1 - 0.12 12.0 0.8 0.2 11.2 0.6 1.3 1 0 0 1 1 1 0 A-kinase anchor protein 2 C-terminus MFS_1 PF07690.11 KLO09679.1 - 5.8e-17 61.4 37.9 5.8e-17 61.4 26.3 2.0 1 1 0 1 1 1 1 Major Facilitator Superfamily MFS_1 PF07690.11 KLO09680.1 - 2.4e-19 69.3 35.8 3.4e-19 68.7 24.8 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Methyltransf_16 PF10294.4 KLO09680.1 - 0.082 12.3 0.0 0.14 11.6 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase Spc7_N PF15402.1 KLO09681.1 - 1.8 6.5 5.7 1.8 6.4 3.9 1.0 1 0 0 1 1 1 0 N-terminus of kinetochore NMS complex subunit Spc7 Abhydrolase_3 PF07859.8 KLO09682.1 - 3.2e-14 53.0 0.0 7.5e-14 51.8 0.0 1.6 2 0 0 2 2 2 1 alpha/beta hydrolase fold COesterase PF00135.23 KLO09682.1 - 4.6e-10 38.8 0.0 1.3e-09 37.2 0.0 1.6 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_5 PF12695.2 KLO09682.1 - 1.4e-06 28.1 0.0 1.6e-06 27.9 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF2424 PF10340.4 KLO09682.1 - 7e-06 24.9 0.0 9.6e-06 24.4 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2424) Abhydrolase_6 PF12697.2 KLO09682.1 - 3.4e-05 23.8 0.0 4.1e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 KLO09682.1 - 0.00014 21.1 0.0 0.00064 18.9 0.0 2.0 3 0 0 3 3 3 1 Prolyl oligopeptidase family DUF1749 PF08538.5 KLO09682.1 - 0.11 11.3 0.0 0.47 9.2 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1749) Lipase_3 PF01764.20 KLO09682.1 - 0.12 11.9 0.0 0.19 11.3 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) Chlorophyllase2 PF12740.2 KLO09682.1 - 0.17 10.7 0.0 0.25 10.1 0.0 1.3 1 0 0 1 1 1 0 Chlorophyllase enzyme RPA_C PF08784.6 KLO09683.1 - 1.3e-15 57.6 0.2 2.9e-15 56.5 0.2 1.6 1 1 0 1 1 1 1 Replication protein A C terminal tRNA_anti-codon PF01336.20 KLO09683.1 - 7.3e-06 25.7 0.0 1.2e-05 25.0 0.0 1.3 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain RNase_PH PF01138.16 KLO09684.1 - 1.9e-18 67.0 0.0 3.4e-18 66.2 0.0 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 AhpC-TSA PF00578.16 KLO09685.1 - 1.1e-39 134.9 0.0 1.6e-39 134.4 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 KLO09685.1 - 1.1e-16 60.6 0.0 1.5e-16 60.2 0.0 1.1 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.4 KLO09685.1 - 1.2e-13 50.4 0.0 2.2e-13 49.6 0.0 1.4 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin DUF1242 PF06842.7 KLO09686.1 - 1.2e-16 59.9 3.5 1.5e-16 59.5 2.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1242) Fungal_trans PF04082.13 KLO09687.1 - 7.4e-21 74.1 0.2 1.5e-20 73.1 0.1 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KLO09687.1 - 3.5e-05 23.6 11.8 8.1e-05 22.4 8.2 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HTH_1 PF00126.22 KLO09687.1 - 0.066 12.9 0.1 0.15 11.8 0.1 1.6 1 0 0 1 1 1 0 Bacterial regulatory helix-turn-helix protein, lysR family Fungal_trans PF04082.13 KLO09688.1 - 8.6e-13 47.7 0.0 1.4e-12 47.0 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KLO09688.1 - 9.7e-05 22.2 13.8 0.00016 21.4 9.6 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Rop-like PF05082.8 KLO09688.1 - 0.093 12.2 0.1 0.87 9.0 0.0 2.6 2 0 0 2 2 2 0 Rop-like Fungal_trans PF04082.13 KLO09690.1 - 4.3e-19 68.4 0.0 9e-19 67.3 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KLO09690.1 - 5.9e-05 22.8 14.7 0.0001 22.1 10.2 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Glyco_hydro_88 PF07470.8 KLO09691.1 - 1.2e-16 60.7 0.2 1.6e-16 60.3 0.2 1.1 1 0 0 1 1 1 1 Glycosyl Hydrolase Family 88 DUF2207 PF09972.4 KLO09691.1 - 0.042 12.4 0.2 3.3 6.2 0.0 2.1 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) Peroxidase_2 PF01328.12 KLO09693.1 - 1.3e-14 53.6 0.0 2e-14 52.9 0.0 1.3 1 0 0 1 1 1 1 Peroxidase, family 2 Gti1_Pac2 PF09729.4 KLO09694.1 - 2e-52 177.4 0.0 5.9e-52 175.9 0.0 1.8 2 1 0 2 2 2 1 Gti1/Pac2 family Zn_clus PF00172.13 KLO09695.1 - 0.0023 17.7 1.6 0.0049 16.7 1.1 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain F-box-like PF12937.2 KLO09696.1 - 0.002 17.8 0.4 0.002 17.8 0.3 1.7 2 0 0 2 2 2 1 F-box-like F-box-like PF12937.2 KLO09697.1 - 0.0026 17.4 1.8 0.004 16.8 0.1 2.1 2 0 0 2 2 2 1 F-box-like DUF3759 PF12585.3 KLO09698.1 - 1.4e-10 40.9 7.4 1.4e-10 40.9 5.1 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF3759) DUF1007 PF06226.8 KLO09698.1 - 0.064 12.9 0.4 0.082 12.6 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1007) HemY_N PF07219.8 KLO09698.1 - 0.66 9.5 2.7 1.2 8.7 1.9 1.4 1 0 0 1 1 1 0 HemY protein N-terminus Chromate_transp PF02417.10 KLO09699.1 - 2.2e-53 180.3 36.5 5.8e-30 104.0 6.7 2.5 3 0 0 3 3 3 2 Chromate transporter N2227 PF07942.7 KLO09700.1 - 3.9e-65 219.5 0.0 5.2e-65 219.0 0.0 1.1 1 0 0 1 1 1 1 N2227-like protein Methyltransf_12 PF08242.7 KLO09700.1 - 1.5e-05 25.4 0.0 0.00014 22.3 0.0 2.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 KLO09700.1 - 4.1e-05 23.3 0.0 7.6e-05 22.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KLO09700.1 - 0.00058 19.8 0.0 0.0015 18.5 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KLO09700.1 - 0.0012 19.3 0.0 0.0061 17.1 0.0 2.2 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 KLO09700.1 - 0.004 17.6 0.0 0.15 12.5 0.0 2.7 3 0 0 3 3 3 1 Methyltransferase domain Pro_dh PF01619.13 KLO09700.1 - 0.077 11.9 0.2 0.11 11.4 0.1 1.2 1 0 0 1 1 1 0 Proline dehydrogenase Clat_adaptor_s PF01217.15 KLO09701.1 - 1.1e-18 67.2 0.0 1.9e-18 66.5 0.0 1.3 1 1 0 1 1 1 1 Clathrin adaptor complex small chain AP-5_subunit_s1 PF15001.1 KLO09701.1 - 0.1 12.5 0.0 0.21 11.5 0.0 1.5 2 0 0 2 2 2 0 AP-5 complex subunit sigma-1 FCH PF00611.18 KLO09702.1 - 1.5e-20 73.1 1.6 3.3e-20 72.0 0.3 2.3 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain SH3_1 PF00018.23 KLO09702.1 - 4.5e-10 38.7 0.1 8.3e-10 37.8 0.1 1.4 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 KLO09702.1 - 8e-07 28.5 0.0 1.7e-06 27.4 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 KLO09702.1 - 0.00016 21.0 0.0 0.0003 20.2 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain EF-hand_1 PF00036.27 KLO09703.1 - 3.7e-26 88.4 0.2 3.2e-07 29.1 0.0 4.6 5 0 0 5 5 5 3 EF hand EF-hand_6 PF13405.1 KLO09703.1 - 3.1e-21 73.2 0.9 3.6e-07 29.5 0.0 4.0 4 0 0 4 4 4 3 EF-hand domain EF-hand_5 PF13202.1 KLO09703.1 - 5.7e-21 72.8 0.5 5.3e-07 28.7 0.0 4.3 4 0 0 4 4 4 3 EF hand EF-hand_7 PF13499.1 KLO09703.1 - 4.7e-20 71.4 6.3 2.8e-09 36.9 0.3 3.8 2 2 1 3 3 3 3 EF-hand domain pair EF-hand_8 PF13833.1 KLO09703.1 - 2.1e-14 52.8 1.1 2.4e-08 33.4 0.0 3.4 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_2 PF09068.6 KLO09703.1 - 0.0031 17.5 0.1 4 7.5 0.0 3.4 3 1 0 4 4 4 1 EF hand PHB_acc_N PF07879.6 KLO09703.1 - 0.03 14.0 0.0 0.18 11.5 0.0 2.2 2 0 0 2 2 2 0 PHB/PHA accumulation regulator DNA-binding domain Toprim_2 PF13155.1 KLO09703.1 - 0.052 13.8 0.2 9.7 6.5 0.0 2.9 1 1 1 2 2 2 0 Toprim-like EF-hand_10 PF14788.1 KLO09703.1 - 0.11 12.1 0.1 3 7.5 0.0 2.8 3 0 0 3 3 3 0 EF hand EF-hand_1 PF00036.27 KLO09705.1 - 2.8e-21 73.1 0.0 4.9e-05 22.3 0.0 4.3 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.1 KLO09705.1 - 2.9e-19 67.1 0.1 5.9e-06 25.7 0.0 4.3 4 0 0 4 4 4 3 EF-hand domain EF-hand_7 PF13499.1 KLO09705.1 - 7.4e-17 61.2 0.0 1.4e-07 31.5 0.0 2.7 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.1 KLO09705.1 - 1.3e-15 55.9 0.0 0.00012 21.2 0.0 4.2 4 0 0 4 4 4 3 EF hand EF-hand_8 PF13833.1 KLO09705.1 - 6.9e-14 51.1 0.4 1.1e-09 37.7 0.1 3.2 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_2 PF09068.6 KLO09705.1 - 0.038 14.0 0.0 45 4.1 0.0 3.6 3 1 0 4 4 4 0 EF hand IKI3 PF04762.7 KLO09706.1 - 1.6e-250 833.7 0.1 1.8e-248 827.0 0.1 2.1 1 1 0 1 1 1 1 IKI3 family RPN7 PF10602.4 KLO09707.1 - 1.7e-55 187.1 0.3 2.4e-55 186.6 0.2 1.2 1 0 0 1 1 1 1 26S proteasome subunit RPN7 PCI PF01399.22 KLO09707.1 - 5.6e-15 55.5 0.7 9.3e-14 51.6 0.1 2.6 2 0 0 2 2 2 1 PCI domain Guanylate_kin PF00625.16 KLO09707.1 - 0.11 11.9 0.1 0.22 10.9 0.0 1.4 1 0 0 1 1 1 0 Guanylate kinase R3H PF01424.17 KLO09708.1 - 6.6e-08 32.1 0.3 1.2e-07 31.3 0.2 1.5 1 0 0 1 1 1 1 R3H domain zf-NF-X1 PF01422.12 KLO09708.1 - 0.00022 21.0 177.1 0.00065 19.5 5.0 13.5 11 2 1 12 12 12 7 NF-X1 type zinc finger Cyclase PF04199.8 KLO09709.1 - 1.4e-29 102.9 0.0 2e-29 102.4 0.0 1.3 1 0 0 1 1 1 1 Putative cyclase Polysacc_deac_1 PF01522.16 KLO09709.1 - 0.0013 18.3 0.0 0.34 10.5 0.0 2.2 2 0 0 2 2 2 2 Polysaccharide deacetylase XH PF03469.9 KLO09710.1 - 0.029 14.0 2.5 0.088 12.4 1.8 1.8 1 1 0 1 1 1 0 XH domain Ferritin_2 PF13668.1 KLO09710.1 - 0.072 13.0 0.1 0.11 12.3 0.1 1.3 1 0 0 1 1 1 0 Ferritin-like domain DUF327 PF03885.8 KLO09710.1 - 0.16 11.8 4.9 0.47 10.2 3.4 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF327) CENP-Q PF13094.1 KLO09711.1 - 0.0005 20.1 0.1 0.00075 19.5 0.0 1.2 1 0 0 1 1 1 1 CENP-Q, a CENPA-CAD centromere complex subunit TMF_DNA_bd PF12329.3 KLO09711.1 - 0.007 16.1 3.1 0.01 15.6 2.1 1.1 1 0 0 1 1 1 1 TATA element modulatory factor 1 DNA binding DUF4201 PF13870.1 KLO09711.1 - 0.053 12.9 1.2 0.072 12.5 0.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4201) IncA PF04156.9 KLO09711.1 - 0.19 11.2 0.8 0.28 10.7 0.5 1.1 1 0 0 1 1 1 0 IncA protein CoA_transf_3 PF02515.12 KLO09712.1 - 2.3e-51 173.7 0.0 2.9e-51 173.4 0.0 1.1 1 0 0 1 1 1 1 CoA-transferase family III GST_N_3 PF13417.1 KLO09713.1 - 3.1e-14 52.9 0.1 6.8e-14 51.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 KLO09713.1 - 8e-10 38.5 0.0 1.6e-09 37.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 KLO09713.1 - 0.0035 17.2 0.0 0.01 15.6 0.0 1.9 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 KLO09713.1 - 0.09 13.2 0.0 0.16 12.4 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain CBM_1 PF00734.13 KLO09714.1 - 7.7e-14 51.0 7.8 2.4e-13 49.5 5.4 1.9 1 0 0 1 1 1 1 Fungal cellulose binding domain Lipase_GDSL PF00657.17 KLO09714.1 - 4.6e-08 33.1 6.5 8e-08 32.3 4.5 1.4 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Glyco_hydro_31 PF01055.21 KLO09715.1 - 6.8e-151 503.0 3.4 1e-150 502.4 2.4 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.1 KLO09715.1 - 1.3e-17 63.4 0.1 3.2e-17 62.1 0.1 1.8 1 0 0 1 1 1 1 Galactose mutarotase-like Gb3_synth PF04572.7 KLO09715.1 - 0.085 12.5 0.1 0.18 11.4 0.1 1.4 1 0 0 1 1 1 0 Alpha 1,4-glycosyltransferase conserved region Cwf_Cwc_15 PF04889.7 KLO09716.1 - 3e-71 240.0 29.4 1.1e-70 238.1 20.4 1.7 1 1 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein CENP-T PF15511.1 KLO09716.1 - 0.0034 16.6 26.5 0.0041 16.4 18.3 1.1 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T Nop14 PF04147.7 KLO09716.1 - 0.009 13.9 35.5 0.011 13.7 24.6 1.0 1 0 0 1 1 1 1 Nop14-like family CDC45 PF02724.9 KLO09716.1 - 0.32 8.9 27.0 0.094 10.7 16.7 1.4 1 1 0 1 1 1 0 CDC45-like protein Prp19_bind PF06991.6 KLO09716.1 - 0.64 9.2 26.6 0.57 9.4 7.4 2.2 2 0 0 2 2 2 0 Splicing factor, Prp19-binding domain Daxx PF03344.10 KLO09716.1 - 0.76 8.1 30.2 1 7.7 21.0 1.1 1 0 0 1 1 1 0 Daxx Family Astro_capsid PF03115.9 KLO09716.1 - 1.5 6.9 7.9 1.9 6.6 5.5 1.1 1 0 0 1 1 1 0 Astrovirus capsid protein precursor Glypican PF01153.14 KLO09716.1 - 8.3 4.8 7.0 10 4.6 4.9 1.3 1 0 0 1 1 1 0 Glypican Aminotran_5 PF00266.14 KLO09718.1 - 2.6e-32 112.0 0.0 5.1e-31 107.7 0.0 2.1 1 1 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.16 KLO09718.1 - 0.00042 19.5 0.0 0.0012 18.0 0.0 1.6 1 1 0 1 1 1 1 Beta-eliminating lyase Uso1_p115_head PF04869.9 KLO09719.1 - 4.9e-46 156.9 0.0 1.7e-44 151.8 0.0 2.6 2 1 0 2 2 2 1 Uso1 / p115 like vesicle tethering protein, head region Uso1_p115_C PF04871.8 KLO09719.1 - 7.3e-08 32.4 18.9 1.3e-07 31.5 13.1 1.4 1 0 0 1 1 1 1 Uso1 / p115 like vesicle tethering protein, C terminal region HEAT_2 PF13646.1 KLO09719.1 - 2.3e-05 24.5 0.4 0.0016 18.6 0.2 3.5 1 1 0 1 1 1 1 HEAT repeats Seryl_tRNA_N PF02403.17 KLO09719.1 - 0.00021 21.2 3.8 0.0021 18.0 3.6 2.0 2 0 0 2 2 1 1 Seryl-tRNA synthetase N-terminal domain DUF4407 PF14362.1 KLO09719.1 - 0.00089 18.3 7.0 0.0015 17.5 4.8 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4407) HEAT PF02985.17 KLO09719.1 - 0.0092 15.9 4.3 0.42 10.8 0.0 4.6 5 0 0 5 5 4 1 HEAT repeat IncA PF04156.9 KLO09719.1 - 0.12 11.9 11.4 0.33 10.5 7.9 1.7 1 0 0 1 1 1 0 IncA protein Bap31 PF05529.7 KLO09719.1 - 0.14 11.5 5.5 0.24 10.8 3.8 1.4 1 0 0 1 1 1 0 B-cell receptor-associated protein 31-like TMF_DNA_bd PF12329.3 KLO09719.1 - 0.57 10.0 11.8 2.1 8.2 2.9 2.6 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding Mo25 PF08569.6 KLO09719.1 - 0.86 8.5 7.4 0.069 12.1 0.2 2.2 2 0 0 2 2 2 0 Mo25-like FlxA PF14282.1 KLO09719.1 - 0.98 9.3 9.2 8.2 6.4 6.5 2.1 1 1 0 1 1 1 0 FlxA-like protein DivIC PF04977.10 KLO09719.1 - 1.1 8.8 8.1 3 7.4 1.4 2.8 2 0 0 2 2 2 0 Septum formation initiator Atg14 PF10186.4 KLO09719.1 - 1.7 7.5 7.7 3.9 6.3 5.4 1.5 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 APG6 PF04111.7 KLO09719.1 - 4.8 6.1 10.7 8.9 5.2 7.4 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 FLO_LFY PF01698.11 KLO09719.1 - 6.6 5.4 12.7 9.7 4.9 8.8 1.2 1 0 0 1 1 1 0 Floricaula / Leafy protein F-box-like PF12937.2 KLO09720.1 - 3.6e-08 33.0 4.1 5.9e-07 29.1 0.1 2.6 3 0 0 3 3 3 2 F-box-like F-box PF00646.28 KLO09720.1 - 0.098 12.3 4.9 0.14 11.8 0.2 2.5 2 0 0 2 2 2 0 F-box domain DUF2002 PF09400.5 KLO09720.1 - 0.12 12.1 0.0 0.25 11.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2002) Peptidase_S64 PF08192.6 KLO09721.1 - 0.11 10.7 0.0 0.2 9.9 0.0 1.3 1 0 0 1 1 1 0 Peptidase family S64 Chordopox_A33R PF05966.7 KLO09724.1 - 0.054 12.2 0.0 0.085 11.6 0.0 1.2 1 0 0 1 1 1 0 Chordopoxvirus A33R protein CAMSAP_CH PF11971.3 KLO09724.1 - 0.094 12.3 0.0 0.2 11.3 0.0 1.5 1 0 0 1 1 1 0 CAMSAP CH domain DUF1129 PF06570.6 KLO09725.1 - 0.067 12.4 0.7 0.13 11.5 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1129) DUF3959 PF13105.1 KLO09725.1 - 0.15 11.3 0.2 0.38 10.0 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3959) Zn_clus PF00172.13 KLO09726.1 - 2.2e-07 30.6 8.7 4.4e-07 29.7 6.0 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ZapA PF05164.8 KLO09729.1 - 0.93 9.5 6.5 1.9 8.5 4.4 1.6 1 1 0 1 1 1 0 Cell division protein ZapA BUD22 PF09073.5 KLO09729.1 - 4.2 6.3 19.5 8.5 5.3 13.5 1.5 1 1 0 1 1 1 0 BUD22 Lactonase PF10282.4 KLO09730.1 - 9.7e-43 146.5 0.0 1.2e-42 146.2 0.0 1.0 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller GAGE PF05831.6 KLO09731.1 - 1.4 9.0 8.2 1.1 9.3 4.9 1.4 1 1 0 1 1 1 0 GAGE protein SOG2 PF10428.4 KLO09732.1 - 0.93 8.0 3.3 0.46 9.0 0.9 1.4 1 1 1 2 2 2 0 RAM signalling pathway protein Malic_M PF03949.10 KLO09737.1 - 1.1e-71 241.4 0.0 1.6e-71 240.8 0.0 1.3 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.14 KLO09737.1 - 1.1e-59 201.0 0.0 1.7e-59 200.4 0.0 1.3 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain DUF998 PF06197.8 KLO09738.1 - 0.066 12.5 3.9 0.24 10.6 1.6 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF998) DUF3292 PF11696.3 KLO09738.1 - 1.6 6.5 3.7 1.5 6.6 1.8 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3292) p450 PF00067.17 KLO09739.1 - 9.7e-73 245.2 0.0 1.2e-72 244.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 F-box PF00646.28 KLO09740.1 - 0.0077 15.8 2.7 0.01 15.4 1.1 1.8 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.2 KLO09740.1 - 0.02 14.5 0.6 0.038 13.7 0.4 1.5 1 0 0 1 1 1 0 F-box-like WD40 PF00400.27 KLO09741.1 - 4.5e-23 80.2 9.8 5.9e-07 29.1 0.1 6.7 6 1 0 6 6 6 5 WD domain, G-beta repeat Frankia_peptide PF14407.1 KLO09741.1 - 0.032 13.9 0.2 6.8 6.5 0.1 2.7 2 0 0 2 2 2 0 Ribosomally synthesized peptide prototyped by Frankia Franean1_4349. DUF3135 PF11333.3 KLO09741.1 - 0.17 12.0 0.4 0.48 10.6 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3135) eIF3_subunit PF08597.5 KLO09742.1 - 3.2e-52 177.5 24.3 3.6e-52 177.3 16.8 1.0 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit DUF2935 PF11155.3 KLO09742.1 - 0.0043 17.1 0.4 0.0083 16.2 0.3 1.5 1 1 0 1 1 1 1 Domain of unknown function (DUF2935) COQ9 PF08511.6 KLO09743.1 - 4.4e-08 32.5 0.0 7.1e-08 31.8 0.0 1.4 1 0 0 1 1 1 1 COQ9 p450 PF00067.17 KLO09744.1 - 5e-67 226.4 0.0 6.1e-67 226.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 KLO09746.1 - 7.5e-64 215.9 0.0 1e-63 215.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Glyco_hydro_53 PF07745.8 KLO09747.1 - 6.3e-86 288.1 0.0 7.3e-86 287.9 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 53 Cellulase PF00150.13 KLO09747.1 - 0.035 13.3 0.0 0.062 12.4 0.0 1.5 2 0 0 2 2 2 0 Cellulase (glycosyl hydrolase family 5) p450 PF00067.17 KLO09748.1 - 7.9e-63 212.5 0.0 9.7e-63 212.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Sensor PF13796.1 KLO09748.1 - 0.18 11.4 2.2 3.8 7.0 0.0 3.0 3 0 0 3 3 3 0 Putative sensor GMC_oxred_C PF05199.8 KLO09749.1 - 6.9e-11 42.6 0.1 1.7e-10 41.3 0.1 1.7 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_N PF00732.14 KLO09749.1 - 0.025 13.7 0.0 4.3 6.4 0.0 2.3 2 0 0 2 2 2 0 GMC oxidoreductase DUF2860 PF11059.3 KLO09749.1 - 0.23 10.4 0.0 0.35 9.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2860) p450 PF00067.17 KLO09750.1 - 1.3e-65 221.8 0.0 1.5e-65 221.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 PsbN PF02468.10 KLO09751.1 - 2.9 7.5 5.0 7.2 6.3 0.5 2.5 1 1 1 2 2 2 0 Photosystem II reaction centre N protein (psbN) RhoGAP PF00620.22 KLO09752.1 - 3.4e-36 124.1 0.0 5.4e-36 123.4 0.0 1.3 1 0 0 1 1 1 1 RhoGAP domain p450 PF00067.17 KLO09753.1 - 2.8e-70 237.1 0.0 3.4e-70 236.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Glyco_hydro_17 PF00332.13 KLO09754.1 - 5e-12 45.4 0.8 5e-12 45.4 0.5 2.2 1 1 0 2 2 2 1 Glycosyl hydrolases family 17 ETRAMP PF09716.5 KLO09754.1 - 0.0036 17.2 0.2 0.0086 16.0 0.2 1.6 1 0 0 1 1 1 1 Malarial early transcribed membrane protein (ETRAMP) DUF1183 PF06682.7 KLO09754.1 - 0.041 13.5 0.5 0.041 13.5 0.4 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1183) DUF2116 PF09889.4 KLO09754.1 - 0.08 12.7 0.1 0.15 11.9 0.1 1.4 1 0 0 1 1 1 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) DUF2763 PF10961.3 KLO09754.1 - 0.19 12.1 1.4 0.4 11.1 0.3 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2763) Abhydrolase_2 PF02230.11 KLO09755.1 - 1.8e-10 40.6 0.0 4.9e-10 39.2 0.0 1.7 1 1 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_6 PF12697.2 KLO09755.1 - 3.2e-06 27.2 2.5 5.4e-06 26.4 1.8 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KLO09755.1 - 0.00035 20.3 0.0 0.0006 19.5 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family LRR_6 PF13516.1 KLO09757.1 - 2.8e-05 23.7 1.3 0.43 10.7 0.0 4.5 5 0 0 5 5 5 2 Leucine Rich repeat LRR_4 PF12799.2 KLO09757.1 - 0.033 13.7 4.1 9.8 5.9 0.0 4.2 4 1 0 4 4 4 0 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KLO09757.1 - 0.1 12.3 4.4 5.5 6.8 0.0 3.9 4 0 0 4 4 4 0 Leucine rich repeat LRR_1 PF00560.28 KLO09757.1 - 0.19 11.8 3.8 29 5.2 0.0 4.8 5 0 0 5 5 5 0 Leucine Rich Repeat Erg28 PF03694.8 KLO09758.1 - 2.9e-37 127.0 6.9 3.5e-37 126.8 4.8 1.1 1 0 0 1 1 1 1 Erg28 like protein Herpes_BMRF2 PF04633.7 KLO09758.1 - 0.003 16.5 2.0 0.0035 16.3 1.3 1.2 1 1 0 1 1 1 1 Herpesvirus BMRF2 protein Dynamin_M PF01031.15 KLO09760.1 - 1e-22 80.2 0.2 1.1e-15 57.2 0.0 2.8 3 0 0 3 3 3 2 Dynamin central region Dynamin_N PF00350.18 KLO09760.1 - 2.1e-20 73.2 0.0 6.6e-20 71.5 0.0 1.8 1 1 0 1 1 1 1 Dynamin family GED PF02212.13 KLO09760.1 - 2.6e-06 27.2 0.0 8.3e-06 25.6 0.0 1.9 1 0 0 1 1 1 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.18 KLO09760.1 - 1.3e-05 25.1 0.0 0.00034 20.5 0.0 2.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 KLO09760.1 - 0.033 14.6 0.0 0.12 12.8 0.0 2.0 1 0 0 1 1 1 0 Miro-like protein AAA_29 PF13555.1 KLO09760.1 - 0.057 12.9 0.0 0.13 11.7 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Dynamin_N PF00350.18 KLO09761.1 - 2.5e-27 95.7 0.0 1.2e-26 93.5 0.0 2.0 2 0 0 2 2 2 1 Dynamin family Dynamin_M PF01031.15 KLO09761.1 - 1.2e-23 83.4 0.0 3.3e-19 68.7 0.0 2.2 1 1 1 2 2 2 2 Dynamin central region MMR_HSR1 PF01926.18 KLO09761.1 - 1.7e-06 27.9 0.0 1.4e-05 25.0 0.0 2.2 1 1 0 1 1 1 1 50S ribosome-binding GTPase GED PF02212.13 KLO09761.1 - 3.6e-05 23.5 0.0 0.00053 19.8 0.0 2.6 2 0 0 2 2 2 1 Dynamin GTPase effector domain Miro PF08477.8 KLO09761.1 - 0.0017 18.8 0.0 0.0047 17.4 0.0 1.8 1 0 0 1 1 1 1 Miro-like protein AAA_29 PF13555.1 KLO09761.1 - 0.02 14.4 0.1 0.041 13.4 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_16 PF13191.1 KLO09761.1 - 0.027 14.4 0.2 0.8 9.6 0.0 2.7 2 0 0 2 2 2 0 AAA ATPase domain ABC_tran PF00005.22 KLO09761.1 - 0.11 12.8 0.0 0.27 11.5 0.0 1.7 1 0 0 1 1 1 0 ABC transporter Shugoshin_N PF07558.6 KLO09761.1 - 0.53 10.0 4.2 1.8 8.3 0.0 3.1 3 0 0 3 3 3 0 Shugoshin N-terminal coiled-coil region p450 PF00067.17 KLO09762.1 - 1.8e-59 201.5 0.0 2.6e-59 200.9 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 Fra10Ac1 PF09725.4 KLO09763.1 - 1.9e-39 134.3 0.5 2.8e-39 133.8 0.3 1.3 1 0 0 1 1 1 1 Folate-sensitive fragile site protein Fra10Ac1 DUF4569 PF15133.1 KLO09763.1 - 0.56 9.5 2.9 0.83 8.9 2.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4569) S-antigen PF05756.6 KLO09763.1 - 0.76 9.7 3.4 1.4 8.9 2.3 1.6 1 0 0 1 1 1 0 S-antigen protein DUF4637 PF15470.1 KLO09763.1 - 0.78 9.3 12.4 1.7 8.2 8.6 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) DUF1510 PF07423.6 KLO09763.1 - 1.2 8.4 8.2 1.6 8.0 5.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) CDC45 PF02724.9 KLO09763.1 - 7.6 4.4 17.6 9.2 4.1 12.2 1.1 1 0 0 1 1 1 0 CDC45-like protein Methyltransf_28 PF02636.12 KLO09764.1 - 1.6e-58 198.0 0.0 2.1e-58 197.7 0.0 1.1 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase eIF-6 PF01912.13 KLO09765.1 - 5.6e-85 283.4 0.2 7.5e-85 283.0 0.1 1.2 1 0 0 1 1 1 1 eIF-6 family AhpC-TSA_2 PF13911.1 KLO09766.1 - 8e-18 64.4 0.0 1.5e-17 63.5 0.0 1.4 1 0 0 1 1 1 1 AhpC/TSA antioxidant enzyme AhpC-TSA PF00578.16 KLO09766.1 - 0.00046 19.8 0.0 0.0006 19.4 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 KLO09766.1 - 0.09 12.3 0.0 0.13 11.8 0.0 1.1 1 0 0 1 1 1 0 Redoxin Aa_trans PF01490.13 KLO09767.1 - 7.7e-84 281.5 27.8 9e-84 281.3 19.3 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein DUF3816 PF12822.2 KLO09768.1 - 0.072 12.9 9.2 0.039 13.8 2.9 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3816) Methyltransf_2 PF00891.13 KLO09769.1 - 2.9e-30 105.2 0.0 1.1e-29 103.3 0.0 1.8 1 1 0 1 1 1 1 O-methyltransferase Methyltransf_23 PF13489.1 KLO09769.1 - 8.2e-05 22.3 0.0 0.00016 21.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KLO09769.1 - 0.0013 19.3 0.0 0.0098 16.4 0.0 2.4 2 1 0 2 2 2 1 Methyltransferase domain MTS PF05175.9 KLO09769.1 - 0.026 13.8 0.0 0.053 12.8 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain F-box-like PF12937.2 KLO09770.1 - 7.5e-06 25.5 0.3 2.4e-05 23.9 0.2 2.0 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KLO09770.1 - 1.1e-05 24.9 0.1 3.6e-05 23.2 0.1 2.0 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 KLO09772.1 - 0.0035 17.0 0.0 0.013 15.2 0.0 2.0 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KLO09772.1 - 0.0044 16.6 0.0 0.017 14.7 0.0 2.1 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 KLO09773.1 - 3.7e-06 26.5 9.4 1.4e-05 24.7 4.8 2.6 2 1 0 2 2 2 1 F-box-like PTPlike_phytase PF14566.1 KLO09774.1 - 2.5e-08 34.0 0.0 3.5e-08 33.6 0.0 1.2 1 0 0 1 1 1 1 Inositol hexakisphosphate DSPc PF00782.15 KLO09774.1 - 1e-05 25.1 0.0 1.7e-05 24.4 0.0 1.5 1 1 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 KLO09774.1 - 0.0022 17.3 0.0 0.0026 17.1 0.0 1.1 1 0 0 1 1 1 1 Protein-tyrosine phosphatase CDKN3 PF05706.7 KLO09774.1 - 0.087 12.2 0.0 0.17 11.3 0.0 1.5 1 0 0 1 1 1 0 Cyclin-dependent kinase inhibitor 3 (CDKN3) APH PF01636.18 KLO09775.1 - 2.5e-10 40.4 0.0 1.8e-09 37.7 0.0 2.2 1 1 0 1 1 1 1 Phosphotransferase enzyme family DUF1679 PF07914.6 KLO09775.1 - 0.037 12.6 0.0 0.082 11.5 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1679) F-box-like PF12937.2 KLO09776.1 - 0.0001 21.9 6.1 0.00058 19.5 4.3 2.3 1 1 0 1 1 1 1 F-box-like APH PF01636.18 KLO09777.1 - 1.4e-13 51.1 0.3 2.5e-13 50.3 0.2 1.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family Fructosamin_kin PF03881.9 KLO09777.1 - 0.044 12.7 0.0 3.7 6.4 0.0 2.2 2 0 0 2 2 2 0 Fructosamine kinase APH PF01636.18 KLO09778.1 - 1.4e-11 44.6 0.6 3.9e-09 36.5 0.1 3.1 2 1 0 2 2 2 2 Phosphotransferase enzyme family DUF1679 PF07914.6 KLO09778.1 - 0.13 10.8 0.0 0.24 9.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) 4HBT PF03061.17 KLO09779.1 - 2.1e-11 43.7 0.0 3.3e-11 43.1 0.0 1.3 1 0 0 1 1 1 1 Thioesterase superfamily 4HBT_3 PF13622.1 KLO09779.1 - 0.00052 19.8 0.0 0.0011 18.7 0.0 1.5 1 1 0 1 1 1 1 Thioesterase-like superfamily F-box-like PF12937.2 KLO09780.1 - 0.0067 16.1 6.2 0.047 13.4 4.3 2.3 1 1 0 1 1 1 1 F-box-like F-box-like PF12937.2 KLO09785.1 - 1.4e-06 27.8 2.1 6.5e-06 25.7 1.5 2.1 1 1 0 1 1 1 1 F-box-like Pkinase PF00069.20 KLO09787.1 - 2.5e-38 131.7 0.0 8.7e-38 129.9 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KLO09787.1 - 2.3e-34 118.6 0.0 2e-33 115.5 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KLO09787.1 - 0.0016 17.4 0.1 0.051 12.5 0.0 2.2 1 1 0 1 1 1 1 Kinase-like CDC45 PF02724.9 KLO09788.1 - 0.67 7.9 7.1 0.84 7.5 4.9 1.1 1 0 0 1 1 1 0 CDC45-like protein NOA36 PF06524.7 KLO09788.1 - 2 7.6 6.4 2.7 7.1 4.5 1.2 1 0 0 1 1 1 0 NOA36 protein TRAP_alpha PF03896.11 KLO09788.1 - 2.9 6.8 5.6 4.1 6.3 3.9 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Nop14 PF04147.7 KLO09788.1 - 5.5 4.7 14.7 7.4 4.3 10.2 1.1 1 0 0 1 1 1 0 Nop14-like family Pkinase PF00069.20 KLO09789.1 - 1.2e-44 152.4 0.0 1.8e-44 151.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KLO09789.1 - 2.3e-42 144.8 0.0 4e-42 144.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KLO09789.1 - 1.3e-06 27.5 0.0 2.8e-06 26.5 0.0 1.4 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.17 KLO09789.1 - 0.054 12.8 0.1 0.45 9.8 0.0 2.1 2 0 0 2 2 2 0 RIO1 family APH PF01636.18 KLO09789.1 - 0.12 12.1 0.0 0.27 10.9 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pkinase_Tyr PF07714.12 KLO09790.1 - 3.4e-45 154.1 0.0 4.7e-45 153.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 KLO09790.1 - 3.1e-40 137.9 0.0 4.2e-40 137.5 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.1 KLO09790.1 - 1.9e-06 27.0 0.0 2.7e-06 26.5 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 KLO09790.1 - 0.051 12.6 0.0 0.094 11.7 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.20 KLO09791.1 - 3e-42 144.5 0.0 4.2e-42 144.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KLO09791.1 - 7.5e-39 133.3 0.0 1e-38 132.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KLO09791.1 - 0.00043 19.3 0.0 0.00065 18.7 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Pkinase PF00069.20 KLO09792.1 - 1.7e-46 158.4 0.0 2.4e-46 157.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KLO09792.1 - 1.1e-41 142.6 0.0 1.5e-41 142.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KLO09792.1 - 3e-05 23.1 0.0 4.8e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 KLO09792.1 - 0.0046 16.7 0.0 0.012 15.3 0.0 2.0 1 1 0 1 1 1 1 Phosphotransferase enzyme family Pkinase PF00069.20 KLO09794.1 - 2.1e-42 145.0 0.0 3.3e-42 144.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KLO09794.1 - 1.2e-39 135.9 0.0 1.7e-39 135.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KLO09794.1 - 0.00012 21.1 0.0 0.0002 20.3 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 KLO09794.1 - 0.015 15.0 0.0 0.025 14.2 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family RIO1 PF01163.17 KLO09794.1 - 0.051 12.9 0.0 0.17 11.1 0.0 1.8 2 0 0 2 2 2 0 RIO1 family Herpes_gI PF01688.12 KLO09795.1 - 0.075 12.1 0.0 0.082 12.0 0.0 1.0 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein I DDE_3 PF13358.1 KLO09796.1 - 0.0023 17.6 0.0 0.0063 16.2 0.0 1.8 1 1 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.11 KLO09796.1 - 0.1 12.4 0.4 0.77 9.6 0.2 2.3 2 0 0 2 2 2 0 Tc5 transposase DNA-binding domain DUF1793 PF08760.6 KLO09797.1 - 9.1e-30 103.7 0.0 1.6e-29 102.9 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1793) Bac_rhamnosid PF05592.6 KLO09797.1 - 0.0033 15.7 0.0 0.0076 14.5 0.0 1.5 1 1 0 1 1 1 1 Bacterial alpha-L-rhamnosidase Peptidase_M76 PF09768.4 KLO09798.1 - 9.1e-30 103.3 0.7 1e-21 77.1 0.0 2.1 2 0 0 2 2 2 2 Peptidase M76 family DUF1772 PF08592.6 KLO09799.1 - 1 9.0 6.6 0.48 10.1 0.1 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF1772) Peptidase_C14 PF00656.17 KLO09800.1 - 1.6e-20 73.8 0.0 2.5e-20 73.2 0.0 1.3 1 0 0 1 1 1 1 Caspase domain Peptidase_M76 PF09768.4 KLO09801.1 - 4e-42 143.5 4.6 4.6e-42 143.4 3.2 1.0 1 0 0 1 1 1 1 Peptidase M76 family Dicty_spore_N PF04562.7 KLO09801.1 - 0.022 15.0 1.7 2 8.7 0.1 2.1 1 1 1 2 2 2 0 Dictyostelium spore coat protein, N terminus zf-H2C2_5 PF13909.1 KLO09801.1 - 2.1 8.7 6.4 0.59 10.4 1.8 2.0 2 0 0 2 2 2 0 C2H2-type zinc-finger domain ASFV_360 PF01671.11 KLO09808.1 - 0.033 13.5 0.3 0.074 12.4 0.1 1.5 1 1 0 1 1 1 0 African swine fever virus multigene family 360 protein DUF1854 PF08909.6 KLO09821.1 - 0.074 12.6 0.0 0.11 12.1 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1854) Zip PF02535.17 KLO09830.1 - 0.87 8.5 12.5 1.3 7.9 8.7 1.4 1 0 0 1 1 1 0 ZIP Zinc transporter AAA PF00004.24 KLO09831.1 - 1.7e-41 141.4 0.0 3.5e-41 140.4 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 KLO09831.1 - 2.8e-06 27.0 0.0 1e-05 25.2 0.0 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 KLO09831.1 - 9.5e-06 25.7 0.0 0.00057 20.0 0.0 2.6 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 KLO09831.1 - 0.00022 21.2 0.0 0.00061 19.8 0.0 1.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_2 PF07724.9 KLO09831.1 - 0.00022 21.1 0.0 0.00057 19.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) DUF815 PF05673.8 KLO09831.1 - 0.00036 19.5 0.0 0.00063 18.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_17 PF13207.1 KLO09831.1 - 0.0016 19.2 0.1 0.0052 17.6 0.1 2.1 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 KLO09831.1 - 0.0031 17.2 0.2 0.0073 16.0 0.1 1.6 1 0 0 1 1 1 1 Part of AAA domain RuvB_N PF05496.7 KLO09831.1 - 0.0041 16.2 0.0 0.0076 15.3 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus Zeta_toxin PF06414.7 KLO09831.1 - 0.011 14.7 0.0 0.02 14.0 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin AAA_28 PF13521.1 KLO09831.1 - 0.013 15.4 0.0 0.025 14.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.1 KLO09831.1 - 0.015 15.1 0.0 0.03 14.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain Sigma54_activ_2 PF14532.1 KLO09831.1 - 0.016 15.2 0.0 0.033 14.2 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_3 PF07726.6 KLO09831.1 - 0.023 14.2 0.0 0.049 13.2 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) NTPase_1 PF03266.10 KLO09831.1 - 0.033 13.8 0.1 0.11 12.2 0.0 1.8 2 0 0 2 2 2 0 NTPase IstB_IS21 PF01695.12 KLO09831.1 - 0.034 13.5 0.0 0.061 12.7 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein RNA_helicase PF00910.17 KLO09831.1 - 0.035 14.2 0.0 0.084 13.0 0.0 1.7 1 0 0 1 1 1 0 RNA helicase AAA_14 PF13173.1 KLO09831.1 - 0.036 13.9 0.0 0.062 13.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain Arch_ATPase PF01637.13 KLO09831.1 - 0.037 13.7 0.0 5.5 6.6 0.0 2.4 1 1 1 2 2 2 0 Archaeal ATPase TIP49 PF06068.8 KLO09831.1 - 0.039 12.6 0.0 0.084 11.5 0.0 1.5 1 0 0 1 1 1 0 TIP49 C-terminus AAA_24 PF13479.1 KLO09831.1 - 0.039 13.5 0.0 0.11 12.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.16 KLO09831.1 - 0.049 12.7 0.0 0.11 11.6 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_18 PF13238.1 KLO09831.1 - 0.059 13.6 0.0 0.15 12.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.21 KLO09831.1 - 0.078 12.4 0.0 0.22 11.0 0.0 1.6 1 1 0 1 1 1 0 Sigma-54 interaction domain AAA_25 PF13481.1 KLO09831.1 - 0.11 11.9 0.1 0.33 10.3 0.0 1.8 1 1 1 2 2 2 0 AAA domain RRM_5 PF13893.1 KLO09832.1 - 0.00063 19.5 0.0 0.0015 18.3 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 KLO09832.1 - 0.021 14.4 0.0 0.05 13.2 0.0 1.6 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KLO09832.1 - 0.035 14.0 0.0 0.1 12.6 0.0 1.7 1 0 0 1 1 1 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) GST_N_2 PF13409.1 KLO09833.1 - 3.4e-21 75.0 0.1 1.3e-20 73.1 0.0 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 KLO09833.1 - 9.1e-16 57.5 0.1 1.8e-15 56.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 KLO09833.1 - 8.8e-10 38.4 0.1 1.5e-09 37.7 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 KLO09833.1 - 2.7e-05 24.5 0.0 4.9e-05 23.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 KLO09833.1 - 0.00019 21.5 0.0 0.0046 17.1 0.0 2.6 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain ubiquitin PF00240.18 KLO09834.1 - 4.1e-14 51.7 0.0 6.6e-14 51.0 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 KLO09834.1 - 3.3e-07 29.9 0.0 5.8e-07 29.1 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ndufs5 PF10200.4 KLO09835.1 - 2e-05 24.4 0.4 2.5e-05 24.1 0.3 1.2 1 0 0 1 1 1 1 NADH:ubiquinone oxidoreductase, NDUFS5-15kDa Cmc1 PF08583.5 KLO09835.1 - 4.2e-05 23.2 3.5 6.3e-05 22.6 2.4 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like CHCH PF06747.8 KLO09835.1 - 0.0044 16.9 2.4 0.006 16.4 0.8 1.8 1 1 1 2 2 2 2 CHCH domain DUF3128 PF11326.3 KLO09835.1 - 0.0066 16.5 3.2 0.013 15.5 2.2 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF3128) UPF0203 PF05254.7 KLO09835.1 - 0.04 13.7 1.6 0.063 13.1 1.1 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0203) DUF1886 PF09171.5 KLO09835.1 - 0.092 11.7 0.0 0.11 11.5 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF1886) Pet191_N PF10203.4 KLO09835.1 - 0.12 12.4 2.5 0.23 11.5 1.7 1.5 1 1 0 1 1 1 0 Cytochrome c oxidase assembly protein PET191 TFIIE_alpha PF02002.12 KLO09836.1 - 2.4e-18 65.5 0.3 5.4e-18 64.4 0.2 1.5 1 0 0 1 1 1 1 TFIIE alpha subunit TF_Zn_Ribbon PF08271.7 KLO09836.1 - 0.0018 17.5 2.5 0.0027 16.9 1.0 1.8 2 0 0 2 2 2 1 TFIIB zinc-binding TFIIE-A_C-term PF11521.3 KLO09836.1 - 0.0026 17.6 0.2 0.0068 16.3 0.2 1.7 1 0 0 1 1 1 1 C-terminal general transcription factor TFIIE alpha RecO_N_2 PF13114.1 KLO09836.1 - 0.068 12.8 0.0 0.12 12.0 0.0 1.3 1 0 0 1 1 1 0 RecO N terminal zf-C2H2_6 PF13912.1 KLO09836.1 - 0.086 12.7 0.1 0.086 12.7 0.1 2.3 3 0 0 3 3 3 0 C2H2-type zinc finger zf-TFIIB PF13453.1 KLO09836.1 - 0.13 11.4 0.4 0.32 10.2 0.3 1.7 1 0 0 1 1 1 0 Transcription factor zinc-finger zf-C2H2_4 PF13894.1 KLO09836.1 - 0.22 11.9 0.6 4.8 7.7 0.0 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger DUF1075 PF06388.6 KLO09837.1 - 0.12 11.9 0.7 0.32 10.6 0.5 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1075) DUF89 PF01937.14 KLO09838.1 - 2.1e-95 319.5 0.5 2.5e-95 319.3 0.4 1.0 1 0 0 1 1 1 1 Protein of unknown function DUF89 GST_N_2 PF13409.1 KLO09840.1 - 1.4e-20 73.0 0.0 3.5e-20 71.7 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 KLO09840.1 - 6.4e-16 58.0 0.0 1.2e-15 57.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 KLO09840.1 - 2e-09 37.2 0.0 3.5e-09 36.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 KLO09840.1 - 7.2e-06 26.3 0.0 1.3e-05 25.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 KLO09840.1 - 0.0001 22.4 0.1 0.0014 18.8 0.0 2.4 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain DUF1092 PF06485.6 KLO09840.1 - 0.16 10.8 0.0 0.22 10.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1092) LRR_6 PF13516.1 KLO09841.1 - 8.9e-05 22.1 10.9 0.36 11.0 0.1 6.5 8 0 0 8 8 8 2 Leucine Rich repeat LRR_7 PF13504.1 KLO09841.1 - 0.097 12.9 9.4 1e+02 3.8 0.0 6.6 7 0 0 7 7 7 0 Leucine rich repeat DUF1232 PF06803.7 KLO09842.1 - 0.67 9.4 5.2 0.13 11.6 1.2 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1232) OPT PF03169.10 KLO09843.1 - 9e-185 615.6 65.8 1e-184 615.4 45.6 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein DUF1770 PF08589.5 KLO09844.1 - 3.5e-09 37.1 0.0 5.4e-09 36.5 0.0 1.3 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1770) zf-Apc11 PF12861.2 KLO09845.1 - 0.37 10.6 1.7 0.37 10.6 0.4 1.6 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger PIG-L PF02585.12 KLO09846.1 - 2e-21 76.8 0.0 2.8e-21 76.3 0.0 1.2 1 0 0 1 1 1 1 GlcNAc-PI de-N-acetylase APG12 PF04110.8 KLO09847.1 - 4.1e-30 103.8 0.0 4.9e-30 103.5 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 Atg8 PF02991.11 KLO09847.1 - 0.0034 17.3 0.0 0.0039 17.1 0.0 1.1 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like Rotamase PF00639.16 KLO09849.1 - 3.7e-19 69.2 0.0 4.6e-19 68.9 0.0 1.1 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_3 PF13616.1 KLO09849.1 - 1.4e-17 64.0 0.0 1.9e-17 63.5 0.0 1.2 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_2 PF13145.1 KLO09849.1 - 5.9e-06 26.9 0.0 6.8e-06 26.7 0.0 1.1 1 0 0 1 1 1 1 PPIC-type PPIASE domain ABC_tran PF00005.22 KLO09850.1 - 1.8e-24 86.5 0.2 1e-14 55.0 0.0 2.8 2 1 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 KLO09850.1 - 6.6e-12 45.9 0.1 0.00083 19.4 0.0 3.4 2 1 1 3 3 3 3 AAA domain SMC_N PF02463.14 KLO09850.1 - 3.6e-10 39.4 1.4 0.0056 15.9 0.0 3.2 2 1 1 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_15 PF13175.1 KLO09850.1 - 1.2e-05 24.5 0.1 0.051 12.6 0.0 3.1 3 0 0 3 3 3 2 AAA ATPase domain AAA_22 PF13401.1 KLO09850.1 - 0.00033 20.7 0.0 0.00067 19.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain SbcCD_C PF13558.1 KLO09850.1 - 0.0025 17.6 0.1 3.3 7.7 0.0 3.5 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit DUF258 PF03193.11 KLO09850.1 - 0.0056 15.8 0.0 0.0094 15.1 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Lactococcin PF04369.8 KLO09850.1 - 0.0094 15.8 0.0 3.4 7.6 0.0 2.9 3 0 0 3 3 3 1 Lactococcin-like family PduV-EutP PF10662.4 KLO09850.1 - 0.014 14.8 0.1 0.066 12.6 0.0 2.0 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Miro PF08477.8 KLO09850.1 - 0.023 15.1 0.1 0.11 12.9 0.0 2.2 3 0 0 3 3 3 0 Miro-like protein AAA_16 PF13191.1 KLO09850.1 - 0.033 14.1 0.0 0.11 12.4 0.0 1.9 2 0 0 2 2 2 0 AAA ATPase domain AAA_13 PF13166.1 KLO09850.1 - 0.054 11.9 0.3 0.8 8.0 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.1 KLO09850.1 - 0.062 13.6 1.3 0.14 12.4 0.9 1.6 1 0 0 1 1 1 0 AAA domain NACHT PF05729.7 KLO09850.1 - 0.1 12.2 0.0 0.19 11.3 0.0 1.5 1 0 0 1 1 1 0 NACHT domain PIG-S PF10510.4 KLO09851.1 - 2.7e-118 395.9 3.5 1.8e-107 360.1 0.1 2.0 1 1 1 2 2 2 2 Phosphatidylinositol-glycan biosynthesis class S protein Rep_fac-A_3 PF08661.6 KLO09852.1 - 4.7e-23 81.1 0.1 5.5e-23 80.9 0.1 1.0 1 0 0 1 1 1 1 Replication factor A protein 3 Glyco_hydro_1 PF00232.13 KLO09853.1 - 1.3e-108 363.1 0.5 1.5e-108 362.9 0.3 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 1 UQ_con PF00179.21 KLO09854.1 - 7.4e-54 180.9 0.0 8.3e-54 180.8 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 KLO09854.1 - 0.00013 21.7 0.0 0.00016 21.4 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 KLO09854.1 - 0.0022 17.8 0.0 0.0026 17.6 0.0 1.3 1 0 0 1 1 1 1 RWD domain UEV PF05743.8 KLO09854.1 - 0.045 13.4 0.3 0.081 12.6 0.2 1.4 1 1 0 1 1 1 0 UEV domain PIG-L PF02585.12 KLO09855.1 - 3.3e-14 53.5 0.0 5e-14 52.9 0.0 1.3 1 0 0 1 1 1 1 GlcNAc-PI de-N-acetylase Myb_DNA-binding PF00249.26 KLO09856.1 - 2.7e-13 49.7 0.0 1.9e-05 24.6 0.0 2.5 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 KLO09856.1 - 2.5e-09 37.0 0.1 0.0011 19.0 0.0 2.6 2 0 0 2 2 2 2 Myb-like DNA-binding domain Mlo PF03094.10 KLO09857.1 - 0.12 10.4 0.0 0.19 9.8 0.0 1.2 1 0 0 1 1 1 0 Mlo family Glyco_transf_20 PF00982.16 KLO09858.1 - 1.5e-134 449.0 0.0 8.3e-134 446.6 0.0 2.1 1 1 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.11 KLO09858.1 - 5.5e-71 238.1 0.0 9.7e-71 237.3 0.0 1.3 1 0 0 1 1 1 1 Trehalose-phosphatase DUF791 PF05631.9 KLO09859.1 - 6.9e-74 248.6 6.2 1.3e-73 247.7 4.3 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF791) MFS_1 PF07690.11 KLO09859.1 - 3e-19 68.9 23.2 3e-19 68.9 16.1 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily DUF3784 PF12650.2 KLO09859.1 - 5.9 6.9 9.5 0.52 10.2 0.4 3.2 4 0 0 4 4 4 0 Domain of unknown function (DUF3784) RRM_1 PF00076.17 KLO09860.1 - 3.3e-48 161.1 0.0 5.9e-16 57.8 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KLO09860.1 - 5.6e-35 119.1 0.0 3.6e-10 39.6 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KLO09860.1 - 2.7e-22 78.3 0.0 1.1e-06 28.3 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 KLO09860.1 - 0.00017 21.4 0.0 4.3 7.2 0.0 3.2 3 0 0 3 3 3 2 RNA binding motif Limkain-b1 PF11608.3 KLO09860.1 - 0.0002 21.0 0.0 0.0052 16.5 0.0 2.5 2 0 0 2 2 2 1 Limkain b1 DUF3343 PF11823.3 KLO09860.1 - 0.078 12.2 0.0 0.23 10.7 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3343) Cys_Met_Meta_PP PF01053.15 KLO09862.1 - 1.6e-32 112.2 0.0 2.1e-32 111.8 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.16 KLO09862.1 - 9.7e-05 21.4 0.0 0.00029 19.9 0.0 1.7 2 0 0 2 2 2 1 Aminotransferase class I and II Polysacc_deac_2 PF04748.8 KLO09862.1 - 0.13 11.3 0.0 0.23 10.4 0.0 1.3 1 0 0 1 1 1 0 Divergent polysaccharide deacetylase MFS_1 PF07690.11 KLO09863.1 - 1.5e-12 46.8 63.5 2.3e-11 43.0 24.9 2.8 2 1 0 3 3 3 2 Major Facilitator Superfamily DUF808 PF05661.7 KLO09863.1 - 0.21 10.3 7.1 0.25 10.1 3.6 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF808) Aldo_ket_red PF00248.16 KLO09864.1 - 1.6e-40 138.7 0.1 2.1e-40 138.3 0.1 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Prok-JAB PF14464.1 KLO09869.1 - 0.04 13.4 0.5 0.042 13.4 0.4 1.1 1 0 0 1 1 1 0 Prokaryotic homologs of the JAB domain PBD PF00786.23 KLO09870.1 - 0.00083 19.7 0.5 0.0019 18.5 0.1 1.9 2 0 0 2 2 2 1 P21-Rho-binding domain BolA PF01722.13 KLO09875.1 - 6.7e-14 51.6 0.0 7.1e-14 51.5 0.0 1.1 1 0 0 1 1 1 1 BolA-like protein CitMHS PF03600.11 KLO09876.1 - 4.1e-15 55.1 5.0 4.1e-15 55.1 3.5 2.9 2 1 1 3 3 3 2 Citrate transporter ArsB PF02040.10 KLO09876.1 - 4.4e-14 52.2 3.2 4.4e-14 52.2 2.2 2.6 3 0 0 3 3 3 2 Arsenical pump membrane protein DUF4342 PF14242.1 KLO09876.1 - 0.063 13.0 2.0 0.22 11.3 1.4 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4342) COX4_pro_2 PF07835.7 KLO09877.1 - 4.7 7.2 0.0 4.7 7.2 0.0 2.9 2 1 1 3 3 3 0 Bacterial aa3 type cytochrome c oxidase subunit IV Maf1 PF09174.5 KLO09878.1 - 1.1e-36 126.4 0.2 5.5e-30 104.5 0.0 2.4 2 0 0 2 2 2 2 Maf1 regulator LRR_4 PF12799.2 KLO09879.1 - 5.6e-42 140.7 21.9 3.8e-09 35.9 2.2 6.8 6 1 1 7 7 7 6 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KLO09879.1 - 2.8e-28 97.4 38.9 4.9e-11 42.2 1.3 5.5 2 1 6 8 8 8 7 Leucine rich repeat LRR_1 PF00560.28 KLO09879.1 - 9.9e-19 64.5 23.9 0.78 9.9 0.1 11.2 11 0 0 11 11 11 7 Leucine Rich Repeat LRR_9 PF14580.1 KLO09879.1 - 3.3e-14 52.8 6.3 6e-05 22.6 0.0 3.1 1 1 2 3 3 3 3 Leucine-rich repeat LRR_6 PF13516.1 KLO09879.1 - 1.3e-09 37.1 23.9 2.1 8.6 0.0 10.2 6 3 5 11 11 11 4 Leucine Rich repeat LRR_7 PF13504.1 KLO09879.1 - 1.9e-07 30.1 20.7 3.1 8.3 0.0 9.9 9 2 0 9 9 9 1 Leucine rich repeat FTH PF01827.22 KLO09879.1 - 0.0011 18.6 0.4 0.035 13.6 0.1 2.8 1 1 1 2 2 2 1 FTH domain LRR_5 PF13306.1 KLO09879.1 - 0.072 12.7 0.1 0.41 10.3 0.0 2.0 2 0 0 2 2 2 0 Leucine rich repeats (6 copies) IF4E PF01652.13 KLO09879.1 - 0.1 12.1 0.0 0.5 9.8 0.0 2.0 1 1 0 1 1 1 0 Eukaryotic initiation factor 4E LysM PF01476.15 KLO09880.1 - 0.096 12.5 0.1 0.3 11.0 0.0 1.8 2 0 0 2 2 2 0 LysM domain Peptidase_C14 PF00656.17 KLO09887.1 - 6.9e-38 130.7 0.3 4.3e-37 128.1 0.2 2.0 1 1 0 1 1 1 1 Caspase domain SIMPL PF04402.9 KLO09887.1 - 0.13 12.0 0.0 0.29 10.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF541) p450 PF00067.17 KLO09888.1 - 2e-68 231.0 0.0 2.3e-68 230.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 KLO09889.1 - 1.1e-68 231.8 0.0 1.4e-68 231.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 KLO09890.1 - 1.2e-52 179.0 0.0 1.3e-52 178.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 KLO09891.1 - 1.7e-61 208.2 0.0 8.5e-36 123.4 0.0 2.1 2 0 0 2 2 2 2 Cytochrome P450 p450 PF00067.17 KLO09892.1 - 1.1e-67 228.5 0.0 1.4e-67 228.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF544 PF04424.8 KLO09893.1 - 1.1e-14 54.2 0.0 1.9e-14 53.5 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF544) PFK PF00365.15 KLO09894.1 - 1.4e-162 539.3 0.1 3.9e-96 321.3 0.0 3.1 3 0 0 3 3 3 3 Phosphofructokinase DUF4646 PF15496.1 KLO09894.1 - 0.058 13.4 0.0 0.13 12.2 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4646) UVR PF02151.14 KLO09894.1 - 0.09 12.3 0.0 0.21 11.1 0.0 1.5 1 0 0 1 1 1 0 UvrB/uvrC motif WLM PF08325.5 KLO09895.1 - 4.3e-50 170.1 2.6 4.3e-50 170.1 1.8 2.3 2 1 0 2 2 2 1 WLM domain DUF45 PF01863.12 KLO09895.1 - 1.3e-05 25.1 0.4 1.3e-05 25.1 0.3 2.5 3 0 0 3 3 3 1 Protein of unknown function DUF45 zf-RanBP PF00641.13 KLO09895.1 - 0.00019 20.4 4.9 0.00033 19.6 3.4 1.4 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others SprT-like PF10263.4 KLO09895.1 - 0.0023 17.5 0.1 0.0079 15.8 0.0 1.9 2 0 0 2 2 2 1 SprT-like family Peptidase_MA_2 PF13485.1 KLO09895.1 - 0.17 11.9 1.0 0.32 11.0 0.1 1.9 2 0 0 2 2 2 0 Peptidase MA superfamily PAXIP1_C PF15364.1 KLO09896.1 - 0.24 11.3 10.9 0.34 10.8 7.5 1.3 1 1 0 1 1 1 0 PAXIP1-associated-protein-1 C term PTIP binding protein BUD22 PF09073.5 KLO09896.1 - 8.1 5.3 9.0 10 5.0 6.2 1.1 1 0 0 1 1 1 0 BUD22 SURF2 PF05477.6 KLO09896.1 - 9.2 5.3 11.8 12 4.9 8.2 1.1 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) p450 PF00067.17 KLO09898.1 - 9.3e-12 44.2 0.0 1.2e-11 43.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 F-box-like PF12937.2 KLO09900.1 - 1.2e-07 31.3 1.6 1.3e-05 24.7 0.2 2.7 3 0 0 3 3 3 2 F-box-like Nucleoside_tran PF01733.13 KLO09901.1 - 4.5e-32 111.4 18.0 1e-18 67.5 10.2 3.4 2 1 0 2 2 2 2 Nucleoside transporter Abhydrolase_3 PF07859.8 KLO09902.1 - 4e-16 59.2 0.0 1.4e-15 57.4 0.0 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.23 KLO09902.1 - 1.1e-07 30.9 0.1 2.6e-07 29.7 0.1 1.5 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_5 PF12695.2 KLO09902.1 - 1e-05 25.3 0.0 1.3e-05 24.9 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF2424 PF10340.4 KLO09902.1 - 0.00026 19.7 0.0 0.00034 19.3 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2424) Abhydrolase_6 PF12697.2 KLO09902.1 - 0.00069 19.5 0.3 0.00089 19.2 0.2 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family FAD_binding_3 PF01494.14 KLO09903.1 - 1.3e-66 225.1 0.0 1.6e-66 224.8 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 KLO09903.1 - 0.00078 19.3 0.2 0.0033 17.3 0.1 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 KLO09903.1 - 0.0016 17.4 0.4 0.0037 16.2 0.0 1.8 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_7 PF13241.1 KLO09903.1 - 0.0065 16.7 0.0 0.043 14.0 0.0 2.1 2 0 0 2 2 2 1 Putative NAD(P)-binding NAD_binding_8 PF13450.1 KLO09903.1 - 0.012 15.6 0.0 0.029 14.3 0.0 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 KLO09903.1 - 0.014 15.8 0.2 0.14 12.5 0.1 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.11 KLO09903.1 - 0.024 14.0 0.2 0.056 12.8 0.1 1.6 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Trp_halogenase PF04820.9 KLO09903.1 - 0.027 13.1 0.0 0.043 12.4 0.0 1.2 1 0 0 1 1 1 0 Tryptophan halogenase Thi4 PF01946.12 KLO09903.1 - 0.07 12.2 0.0 0.13 11.3 0.0 1.3 1 0 0 1 1 1 0 Thi4 family NAD_Gly3P_dh_N PF01210.18 KLO09903.1 - 0.11 12.2 0.0 0.26 10.9 0.0 1.6 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus MFS_1 PF07690.11 KLO09904.1 - 3.7e-32 111.4 43.2 1.3e-25 89.8 11.9 3.0 2 1 0 3 3 3 3 Major Facilitator Superfamily Sugar_tr PF00083.19 KLO09904.1 - 2e-05 23.4 9.7 2e-05 23.4 6.7 2.5 3 1 0 3 3 3 1 Sugar (and other) transporter TRI12 PF06609.8 KLO09904.1 - 2e-05 23.0 27.3 0.00028 19.2 18.9 2.4 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Iron_permease PF04120.7 KLO09904.1 - 0.0079 15.7 0.0 0.019 14.5 0.0 1.6 1 0 0 1 1 1 1 Low affinity iron permease CRAL_TRIO PF00650.15 KLO09905.1 - 7.9e-36 122.9 0.0 1.2e-35 122.3 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 KLO09905.1 - 2.1e-13 50.1 2.4 2.1e-13 50.1 1.6 2.1 2 0 0 2 2 2 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.1 KLO09905.1 - 0.0013 18.7 0.0 0.024 14.5 0.0 2.2 2 0 0 2 2 2 1 Divergent CRAL/TRIO domain Tweety PF04906.8 KLO09907.1 - 0.042 12.2 1.9 0.045 12.1 1.3 1.1 1 0 0 1 1 1 0 Tweety Actin PF00022.14 KLO09910.1 - 1.6e-159 530.6 0.0 1.8e-159 530.4 0.0 1.0 1 0 0 1 1 1 1 Actin ESSS PF10183.4 KLO09910.1 - 0.077 13.4 0.0 0.19 12.1 0.0 1.6 1 1 0 1 1 1 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) Methyltransf_29 PF03141.11 KLO09910.1 - 0.17 10.1 0.0 0.25 9.6 0.0 1.2 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase VWA_2 PF13519.1 KLO09911.1 - 2.1e-11 44.2 1.8 3.3e-11 43.5 0.1 2.1 1 1 1 2 2 2 1 von Willebrand factor type A domain UIM PF02809.15 KLO09911.1 - 2.2e-10 39.1 26.1 0.00014 21.1 1.5 3.9 3 0 0 3 3 3 3 Ubiquitin interaction motif Ssl1 PF04056.9 KLO09911.1 - 1.1e-07 31.6 0.0 2e-07 30.8 0.0 1.4 1 0 0 1 1 1 1 Ssl1-like VWA PF00092.23 KLO09911.1 - 8.1e-06 25.6 0.0 1.4e-05 24.8 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain DUF3608 PF12257.3 KLO09911.1 - 0.11 11.3 0.1 0.17 10.8 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3608) EMG1 PF03587.9 KLO09912.1 - 2.2e-74 249.1 0.0 2.6e-74 248.8 0.0 1.1 1 0 0 1 1 1 1 EMG1/NEP1 methyltransferase SCO1-SenC PF02630.9 KLO09913.1 - 1.2e-55 187.7 0.0 1.6e-55 187.3 0.0 1.1 1 0 0 1 1 1 1 SCO1/SenC AhpC-TSA PF00578.16 KLO09913.1 - 4.3e-08 32.8 0.0 1.2e-07 31.4 0.0 1.8 1 1 0 1 1 1 1 AhpC/TSA family Thioredoxin_8 PF13905.1 KLO09913.1 - 0.00019 21.4 0.0 0.00034 20.6 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin-like NDUF_B7 PF05676.8 KLO09914.1 - 3e-28 97.0 1.0 3.5e-28 96.7 0.7 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) Cmc1 PF08583.5 KLO09914.1 - 0.04 13.6 1.8 0.056 13.2 1.2 1.2 1 0 0 1 1 1 0 Cytochrome c oxidase biogenesis protein Cmc1 like DUF1469 PF07332.6 KLO09916.1 - 0.69 9.6 4.2 1.5 8.5 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1469) GWT1 PF06423.7 KLO09916.1 - 2.9 7.9 12.0 0.35 10.9 2.7 2.6 1 1 1 2 2 2 0 GWT1 zf-MYND PF01753.13 KLO09917.1 - 4.6e-10 39.1 13.2 8e-10 38.4 9.1 1.4 1 0 0 1 1 1 1 MYND finger PolC_DP2 PF03833.8 KLO09917.1 - 0.15 9.7 0.6 0.21 9.2 0.4 1.1 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 FGGY_C PF02782.11 KLO09918.1 - 2.2e-46 157.9 0.1 3.1e-46 157.5 0.0 1.2 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.16 KLO09918.1 - 1.7e-18 66.8 0.0 1.1e-16 60.9 0.0 2.6 2 1 0 2 2 2 1 FGGY family of carbohydrate kinases, N-terminal domain BcrAD_BadFG PF01869.15 KLO09918.1 - 0.039 13.2 0.2 0.15 11.3 0.1 1.9 2 0 0 2 2 2 0 BadF/BadG/BcrA/BcrD ATPase family UPF0075 PF03702.9 KLO09918.1 - 0.059 12.2 0.0 0.12 11.2 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0075) Euplotes_phero PF05842.6 KLO09918.1 - 0.066 13.5 0.0 0.18 12.1 0.0 1.6 1 0 0 1 1 1 0 Euplotes octocarinatus mating pheromone protein JmjC PF02373.17 KLO09920.1 - 7.4e-15 55.1 0.0 2.3e-14 53.5 0.0 1.9 1 0 0 1 1 1 1 JmjC domain, hydroxylase Cupin_8 PF13621.1 KLO09920.1 - 0.0061 16.0 0.0 0.11 12.0 0.0 2.4 1 1 0 1 1 1 1 Cupin-like domain FYVE PF01363.16 KLO09920.1 - 0.012 15.4 2.4 0.012 15.4 1.7 2.4 3 0 0 3 3 3 0 FYVE zinc finger Response_reg PF00072.19 KLO09921.1 - 1.9e-23 82.6 0.0 1e-15 57.7 0.0 2.7 2 0 0 2 2 2 2 Response regulator receiver domain UAA PF08449.6 KLO09922.1 - 4e-71 239.4 5.8 5.9e-71 238.8 4.1 1.2 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.15 KLO09922.1 - 7.1e-05 22.8 1.7 7.1e-05 22.8 1.2 3.5 4 0 0 4 4 4 1 EamA-like transporter family TPT PF03151.11 KLO09922.1 - 0.0024 17.5 0.5 0.0024 17.5 0.3 2.5 2 0 0 2 2 2 1 Triose-phosphate Transporter family EmrE PF13536.1 KLO09922.1 - 0.0033 17.5 0.7 0.0033 17.5 0.5 3.3 4 0 0 4 4 4 1 Multidrug resistance efflux transporter DUF4231 PF14015.1 KLO09922.1 - 0.27 11.2 6.1 0.18 11.8 0.2 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF4231) MIF4G_like PF09088.6 KLO09925.1 - 1.5e-61 207.1 0.0 3.5e-61 205.9 0.0 1.6 1 0 0 1 1 1 1 MIF4G like MIF4G_like_2 PF09090.6 KLO09925.1 - 6.8e-42 143.4 0.3 1.1e-41 142.7 0.2 1.3 1 0 0 1 1 1 1 MIF4G like MIF4G PF02854.14 KLO09925.1 - 0.066 12.6 0.0 1.2 8.5 0.0 2.4 2 0 0 2 2 2 0 MIF4G domain PPR_2 PF13041.1 KLO09926.1 - 1.6e-07 31.2 0.0 0.0035 17.2 0.0 5.2 6 0 0 6 6 6 2 PPR repeat family PPR PF01535.15 KLO09926.1 - 1.1e-06 28.1 0.5 0.16 12.0 0.0 6.1 7 0 0 7 7 7 1 PPR repeat PPR_3 PF13812.1 KLO09926.1 - 7e-06 25.9 2.6 0.43 10.9 0.0 6.0 8 0 0 8 8 8 1 Pentatricopeptide repeat domain PPR_1 PF12854.2 KLO09926.1 - 0.00097 18.5 0.0 13 5.3 0.0 4.6 4 0 0 4 4 4 1 PPR repeat IF3_C PF00707.17 KLO09927.1 - 5.8e-12 45.1 0.0 9.9e-12 44.4 0.0 1.3 1 0 0 1 1 1 1 Translation initiation factor IF-3, C-terminal domain mIF3 PF14877.1 KLO09927.1 - 3.7e-05 23.1 0.2 0.024 14.0 0.0 2.2 1 1 1 2 2 2 2 Mitochondrial translation initiation factor Mito_carr PF00153.22 KLO09929.1 - 1.2e-55 185.2 2.1 1.4e-18 66.3 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein dCMP_cyt_deam_1 PF00383.17 KLO09930.1 - 2.6e-21 75.1 0.1 3.4e-21 74.7 0.1 1.2 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region Bd3614-deam PF14439.1 KLO09930.1 - 5.8e-05 22.9 0.8 0.0013 18.6 0.5 2.2 1 1 0 1 1 1 1 Bd3614-like deaminase APOBEC_N PF08210.6 KLO09930.1 - 0.0079 15.8 0.0 0.011 15.3 0.0 1.2 1 0 0 1 1 1 1 APOBEC-like N-terminal domain Ribonuc_red_sm PF00268.16 KLO09931.1 - 8.5e-05 21.6 0.1 9.8e-05 21.4 0.1 1.1 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain DUF4418 PF14387.1 KLO09931.1 - 0.0047 16.6 1.4 0.0056 16.4 1.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4418) peroxidase PF00141.18 KLO09933.1 - 5.1e-29 101.3 0.0 8.9e-29 100.5 0.0 1.5 1 0 0 1 1 1 1 Peroxidase DUF3415 PF11895.3 KLO09933.1 - 2.8e-23 81.5 1.5 6.6e-23 80.3 1.1 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF3415) DUF627 PF04781.7 KLO09933.1 - 0.11 12.0 0.0 0.19 11.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF627) Glyco_hydro_42 PF02449.10 KLO09933.1 - 0.23 10.5 0.0 0.28 10.2 0.0 1.1 1 0 0 1 1 1 0 Beta-galactosidase peroxidase PF00141.18 KLO09934.1 - 3.1e-30 105.3 0.2 5.2e-30 104.6 0.1 1.4 1 0 0 1 1 1 1 Peroxidase DUF3415 PF11895.3 KLO09934.1 - 6.7e-25 86.7 3.7 1.6e-24 85.5 1.8 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF3415) DUF627 PF04781.7 KLO09934.1 - 0.029 13.9 0.0 0.048 13.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF627) Methyltransf_2 PF00891.13 KLO09938.1 - 6.6e-26 90.9 0.0 1.1e-25 90.2 0.0 1.4 1 0 0 1 1 1 1 O-methyltransferase HNH_2 PF13391.1 KLO09939.1 - 5.7e-07 29.2 0.2 1.4e-06 27.9 0.1 1.7 1 0 0 1 1 1 1 HNH endonuclease AHH PF14412.1 KLO09939.1 - 0.09 12.7 0.2 0.2 11.6 0.0 1.6 2 0 0 2 2 2 0 A nuclease family of the HNH/ENDO VII superfamily with conserved AHH Methyltransf_2 PF00891.13 KLO09940.1 - 1.1e-20 73.8 0.0 1.7e-20 73.2 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase p450 PF00067.17 KLO09941.1 - 7.2e-66 222.6 0.0 8.9e-66 222.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF367 PF04034.8 KLO09941.1 - 0.18 11.4 0.0 0.38 10.3 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF367) Trp_halogenase PF04820.9 KLO09942.1 - 1.3e-31 109.7 0.2 4.5e-29 101.3 0.1 2.6 1 1 0 1 1 1 1 Tryptophan halogenase FAD_binding_3 PF01494.14 KLO09942.1 - 1.3e-13 50.7 0.0 4.7e-12 45.6 0.0 2.3 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.9 KLO09942.1 - 1.3e-05 25.1 0.0 4e-05 23.5 0.0 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 KLO09942.1 - 2.3e-05 23.6 0.6 8.1e-05 21.8 0.4 1.9 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KLO09942.1 - 5.8e-05 23.0 0.3 0.00054 19.9 0.1 2.8 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 KLO09942.1 - 8.4e-05 21.5 0.2 0.00016 20.7 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 KLO09942.1 - 0.00012 21.0 0.1 0.0014 17.6 0.1 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase GIDA PF01134.17 KLO09942.1 - 0.00073 18.4 0.1 0.0013 17.7 0.1 1.4 1 0 0 1 1 1 1 Glucose inhibited division protein A HI0933_like PF03486.9 KLO09942.1 - 0.0048 15.4 0.1 0.0079 14.7 0.1 1.3 1 0 0 1 1 1 1 HI0933-like protein ThiF PF00899.16 KLO09942.1 - 0.0084 15.9 0.4 0.06 13.1 0.2 2.4 3 0 0 3 3 3 1 ThiF family Pyr_redox_3 PF13738.1 KLO09942.1 - 0.057 13.4 0.3 0.17 11.9 0.1 2.1 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Vert_HS_TF PF06546.6 KLO09942.1 - 0.13 11.6 0.0 0.19 11.1 0.0 1.2 1 0 0 1 1 1 0 Vertebrate heat shock transcription factor RhoGAP PF00620.22 KLO09943.1 - 9.5e-34 116.2 0.0 1.6e-33 115.4 0.0 1.3 1 0 0 1 1 1 1 RhoGAP domain CRAL_TRIO_2 PF13716.1 KLO09943.1 - 4.7e-31 107.7 0.2 7.9e-31 106.9 0.1 1.3 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain CRAL_TRIO PF00650.15 KLO09943.1 - 1.6e-05 24.4 0.1 2.8e-05 23.6 0.1 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain p450 PF00067.17 KLO09944.1 - 3.3e-55 187.4 0.0 3.9e-55 187.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 KLO09945.1 - 8.2e-70 235.6 0.0 9.4e-70 235.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Methyltransf_2 PF00891.13 KLO09946.1 - 3.7e-28 98.3 0.0 1.3e-27 96.5 0.0 1.7 1 1 0 1 1 1 1 O-methyltransferase Dimerisation PF08100.6 KLO09946.1 - 5.3e-06 26.1 0.2 1.4e-05 24.7 0.1 1.7 1 0 0 1 1 1 1 Dimerisation domain Methyltransf_12 PF08242.7 KLO09946.1 - 8.9e-05 22.9 0.0 0.00026 21.4 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 KLO09946.1 - 0.00034 21.1 0.0 0.00099 19.6 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KLO09946.1 - 0.0065 16.2 0.0 0.04 13.6 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 KLO09946.1 - 0.009 15.0 0.0 0.019 14.0 0.0 1.6 2 0 0 2 2 2 1 Putative methyltransferase MTS PF05175.9 KLO09946.1 - 0.047 13.0 0.0 0.084 12.2 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain DOT1 PF08123.8 KLO09946.1 - 0.17 11.1 0.0 0.26 10.5 0.0 1.3 1 0 0 1 1 1 0 Histone methylation protein DOT1 p450 PF00067.17 KLO09947.1 - 4.6e-63 213.3 0.0 5.8e-63 213.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 KLO09948.1 - 5.2e-32 110.9 0.0 6.6e-32 110.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 KLO09949.1 - 1.1e-62 212.1 0.0 1.5e-62 211.6 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 FG-GAP_2 PF14312.1 KLO09949.1 - 0.14 12.1 1.2 1.4 9.0 0.1 2.4 2 0 0 2 2 2 0 FG-GAP repeat Glyco_transf_8 PF01501.15 KLO09950.1 - 5.4e-31 107.8 0.1 7e-31 107.4 0.1 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 8 Mannosyl_trans3 PF11051.3 KLO09950.1 - 0.0003 20.2 0.1 0.00045 19.6 0.1 1.1 1 0 0 1 1 1 1 Mannosyltransferase putative Glyco_transf_21 PF13506.1 KLO09950.1 - 0.068 12.4 0.6 0.63 9.3 0.0 2.2 1 1 1 2 2 2 0 Glycosyl transferase family 21 p450 PF00067.17 KLO09951.1 - 2e-51 175.0 0.0 5.8e-28 97.6 0.0 2.1 2 0 0 2 2 2 2 Cytochrome P450 p450 PF00067.17 KLO09952.1 - 2.4e-65 220.8 0.0 2.9e-65 220.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 XPG_I PF00867.13 KLO09954.1 - 9.7e-27 92.8 0.0 2.6e-26 91.4 0.0 1.8 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.12 KLO09954.1 - 4.9e-24 84.5 0.0 9.3e-24 83.6 0.0 1.5 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I_2 PF12813.2 KLO09954.1 - 3e-05 23.6 0.0 4.6e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 XPG domain containing 5_3_exonuc PF01367.15 KLO09954.1 - 8.6e-05 22.7 0.0 0.00019 21.6 0.0 1.5 1 0 0 1 1 1 1 5'-3' exonuclease, C-terminal SAM fold TPR_2 PF07719.12 KLO09954.1 - 0.0043 16.8 0.0 0.012 15.4 0.0 1.8 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_1 PF00515.23 KLO09954.1 - 0.0069 15.9 0.0 0.028 14.0 0.0 2.1 2 0 0 2 2 2 1 Tetratricopeptide repeat HHH_2 PF12826.2 KLO09954.1 - 0.047 13.5 0.0 0.42 10.5 0.0 2.1 2 0 0 2 2 2 0 Helix-hairpin-helix motif DUF99 PF01949.11 KLO09954.1 - 0.11 11.5 0.1 0.21 10.6 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function DUF99 HHH PF00633.18 KLO09954.1 - 0.13 11.9 0.1 0.59 9.9 0.0 2.1 2 0 0 2 2 2 0 Helix-hairpin-helix motif Glyco_hydro_88 PF07470.8 KLO09955.1 - 1.4e-12 47.3 0.3 1.5e-12 47.1 0.2 1.2 1 0 0 1 1 1 1 Glycosyl Hydrolase Family 88 Mito_carr PF00153.22 KLO09956.1 - 6.2e-56 186.0 4.2 5e-18 64.6 0.3 3.7 3 1 0 3 3 3 3 Mitochondrial carrier protein Rif1_N PF12231.3 KLO09957.1 - 0.015 14.2 0.0 0.024 13.5 0.0 1.2 1 0 0 1 1 1 0 Rap1-interacting factor 1 N terminal F-box-like PF12937.2 KLO09960.1 - 0.0084 15.8 0.1 0.022 14.4 0.1 1.7 1 0 0 1 1 1 1 F-box-like F-box-like PF12937.2 KLO09961.1 - 9.9e-05 21.9 0.6 0.0002 21.0 0.4 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KLO09961.1 - 0.0002 20.9 0.2 0.00057 19.4 0.2 1.8 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 KLO09962.1 - 0.00014 21.5 0.1 0.00027 20.5 0.1 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KLO09962.1 - 0.0057 16.2 0.0 0.011 15.4 0.0 1.5 1 0 0 1 1 1 1 F-box domain HpcH_HpaI PF03328.9 KLO09963.1 - 5.2e-33 113.8 0.0 6.6e-33 113.4 0.0 1.1 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family DUF2156 PF09924.4 KLO09963.1 - 0.012 14.4 0.0 0.019 13.8 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2156) PK PF00224.16 KLO09963.1 - 0.014 14.0 2.3 0.2 10.2 0.2 2.2 1 1 1 2 2 2 0 Pyruvate kinase, barrel domain IGPS PF00218.16 KLO09963.1 - 0.027 13.5 0.2 0.14 11.2 0.0 1.9 2 0 0 2 2 2 0 Indole-3-glycerol phosphate synthase Peptidase_S9 PF00326.16 KLO09964.1 - 5.6e-45 153.1 0.1 8.3e-45 152.6 0.1 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 KLO09964.1 - 1.7e-10 40.8 0.0 3.6e-10 39.7 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KLO09964.1 - 4e-08 33.4 0.2 1.3e-07 31.7 0.2 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family AXE1 PF05448.7 KLO09964.1 - 0.004 15.7 0.1 0.11 10.9 0.0 2.2 1 1 0 1 1 1 1 Acetyl xylan esterase (AXE1) PhoPQ_related PF10142.4 KLO09964.1 - 0.099 11.1 0.0 0.55 8.6 0.0 1.9 2 0 0 2 2 2 0 PhoPQ-activated pathogenicity-related protein Alpha_kinase PF02816.13 KLO09967.1 - 7.8e-05 22.4 0.0 0.00012 21.8 0.0 1.4 1 1 0 1 1 1 1 Alpha-kinase family SURF6 PF04935.7 KLO09971.1 - 3.2e-38 131.1 36.1 3.2e-38 131.1 25.0 2.6 2 1 0 2 2 2 1 Surfeit locus protein 6 RRP14 PF15459.1 KLO09971.1 - 8.7e-20 70.5 8.1 8.7e-20 70.5 5.6 5.4 4 1 1 5 5 5 1 60S ribosome biogenesis protein Rrp14 Hydrolase_6 PF13344.1 KLO09972.1 - 4.2e-29 100.4 0.0 6.6e-29 99.7 0.0 1.3 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 KLO09972.1 - 2.1e-14 52.9 0.0 4.2e-14 52.0 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.21 KLO09972.1 - 1.1e-10 42.2 0.0 1.5e-10 41.8 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 KLO09972.1 - 4.3e-06 27.0 0.0 0.00094 19.4 0.0 2.6 2 1 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Ribosomal_L7Ae PF01248.21 KLO09972.1 - 0.0053 16.2 0.0 0.0098 15.3 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family PGP_phosphatase PF09419.5 KLO09972.1 - 0.048 13.0 0.0 0.26 10.6 0.0 1.9 2 0 0 2 2 2 0 Mitochondrial PGP phosphatase PTPA PF03095.10 KLO09973.1 - 5.4e-120 400.0 0.0 6.6e-120 399.8 0.0 1.0 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein 6PF2K PF01591.13 KLO09975.1 - 3.2e-67 225.8 0.2 4.3e-67 225.4 0.2 1.1 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.17 KLO09975.1 - 3.9e-31 108.2 0.0 8.2e-31 107.2 0.0 1.6 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.1 KLO09975.1 - 8.7e-07 28.9 0.0 1.5e-06 28.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 KLO09975.1 - 9.5e-05 23.2 0.9 0.00025 21.8 0.1 2.1 2 1 0 2 2 2 1 AAA domain Zeta_toxin PF06414.7 KLO09975.1 - 0.013 14.5 0.0 0.025 13.6 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin Methyltransf_32 PF13679.1 KLO09975.1 - 0.024 14.3 0.1 0.09 12.4 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase domain GBP PF02263.14 KLO09975.1 - 0.049 12.6 0.0 0.23 10.4 0.0 1.9 2 0 0 2 2 2 0 Guanylate-binding protein, N-terminal domain KTI12 PF08433.5 KLO09975.1 - 0.093 11.9 0.0 0.14 11.3 0.0 1.3 1 0 0 1 1 1 0 Chromatin associated protein KTI12 bZIP_2 PF07716.10 KLO09976.1 - 0.00064 19.4 8.7 0.076 12.8 0.5 2.4 2 0 0 2 2 2 2 Basic region leucine zipper GAS PF13851.1 KLO09976.1 - 0.001 18.2 1.0 0.0012 18.1 0.7 1.1 1 0 0 1 1 1 1 Growth-arrest specific micro-tubule binding Shugoshin_N PF07558.6 KLO09976.1 - 0.0057 16.3 0.8 0.0057 16.3 0.6 1.8 2 0 0 2 2 2 1 Shugoshin N-terminal coiled-coil region DUF1319 PF07028.6 KLO09976.1 - 0.013 15.7 1.2 0.016 15.3 0.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1319) MbeD_MobD PF04899.7 KLO09976.1 - 0.019 14.8 0.3 0.032 14.1 0.2 1.5 1 1 0 1 1 1 0 MbeD/MobD like Rab5-bind PF09311.6 KLO09976.1 - 0.052 13.4 6.5 0.44 10.4 0.3 2.1 1 1 1 2 2 2 0 Rabaptin-like protein DivIC PF04977.10 KLO09976.1 - 0.084 12.3 1.7 0.11 11.9 0.2 1.8 1 1 1 2 2 2 0 Septum formation initiator GvpK PF05121.7 KLO09976.1 - 0.12 12.2 0.5 0.82 9.5 0.1 1.9 1 1 1 2 2 2 0 Gas vesicle protein K bZIP_1 PF00170.16 KLO09976.1 - 0.12 12.3 0.6 0.12 12.3 0.4 2.5 2 1 1 3 3 3 0 bZIP transcription factor PilJ PF13675.1 KLO09976.1 - 0.12 12.6 2.2 0.16 12.3 1.5 1.3 1 0 0 1 1 1 0 Type IV pili methyl-accepting chemotaxis transducer N-term WD40_alt PF14077.1 KLO09976.1 - 0.19 11.3 1.4 1.1 8.9 0.4 2.1 2 0 0 2 2 2 0 Alternative WD40 repeat motif DUF1192 PF06698.6 KLO09976.1 - 0.99 9.2 4.4 0.67 9.8 0.2 2.4 2 1 1 3 3 3 0 Protein of unknown function (DUF1192) DUF4140 PF13600.1 KLO09976.1 - 2 8.8 5.4 12 6.4 3.7 2.0 1 1 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) adh_short_C2 PF13561.1 KLO09980.1 - 1.1e-33 116.9 0.6 1.6e-33 116.4 0.4 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 KLO09980.1 - 8.4e-30 103.8 1.1 1.3e-29 103.2 0.8 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KLO09980.1 - 1.3e-17 64.0 0.4 3.8e-17 62.5 0.3 1.6 1 1 1 2 2 2 1 KR domain Epimerase PF01370.16 KLO09980.1 - 6.5e-05 22.4 0.3 8.2e-05 22.1 0.2 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF4170 PF13773.1 KLO09980.1 - 0.0098 15.7 0.0 0.02 14.8 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4170) 3HCDH_N PF02737.13 KLO09980.1 - 0.014 15.0 0.3 0.22 11.1 0.1 2.4 3 0 0 3 3 3 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain SBP_bac_5 PF00496.17 KLO09980.1 - 0.038 12.8 0.2 0.05 12.4 0.1 1.1 1 0 0 1 1 1 0 Bacterial extracellular solute-binding proteins, family 5 Middle THF_DHG_CYH_C PF02882.14 KLO09980.1 - 0.04 13.0 0.0 0.085 11.9 0.0 1.6 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain HAD PF12710.2 KLO09980.1 - 0.04 14.0 0.2 1.2 9.2 0.0 2.2 1 1 1 2 2 2 0 haloacid dehalogenase-like hydrolase NAD_binding_10 PF13460.1 KLO09980.1 - 0.06 13.3 0.5 0.19 11.7 0.1 1.8 2 0 0 2 2 2 0 NADH(P)-binding GHMP_kinases_C PF08544.8 KLO09980.1 - 0.12 12.6 0.1 0.25 11.5 0.0 1.5 1 0 0 1 1 1 0 GHMP kinases C terminal Rz1 PF06085.6 KLO09982.1 - 5 6.6 8.9 54 3.3 5.2 2.6 2 0 0 2 2 2 0 Lipoprotein Rz1 precursor TIMELESS PF04821.9 KLO09984.1 - 1.6e-49 168.5 1.0 3e-49 167.6 0.0 2.0 2 0 0 2 2 2 1 Timeless protein TIMELESS_C PF05029.8 KLO09984.1 - 3.6e-15 55.9 0.1 3.6e-15 55.9 0.1 3.3 3 0 0 3 3 3 1 Timeless protein C terminal region RNA_pol_Rpb4 PF03874.11 KLO09984.1 - 0.0091 15.9 4.5 0.32 11.0 0.5 3.1 2 0 0 2 2 2 2 RNA polymerase Rpb4 Nol1_Nop2_Fmu PF01189.12 KLO09985.1 - 6.7e-28 97.8 0.0 1.1e-24 87.2 0.0 2.8 2 1 0 2 2 2 2 NOL1/NOP2/sun family LysM PF01476.15 KLO09987.1 - 6e-13 48.4 0.1 1.9e-05 24.4 0.0 2.6 3 0 0 3 3 3 2 LysM domain Kei1 PF08552.6 KLO09989.1 - 0.26 10.9 4.4 9.4 5.8 3.1 2.4 1 1 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 COPI_assoc PF08507.5 KLO09989.1 - 1.1 8.9 7.9 2 8.0 1.0 2.9 3 1 0 3 3 3 0 COPI associated protein Tetraspannin PF00335.15 KLO09989.1 - 1.3 8.2 12.5 0.56 9.4 6.4 1.8 1 1 1 2 2 2 0 Tetraspanin family Phage_holin_1 PF04531.8 KLO09989.1 - 4.3 7.4 5.5 2.4 8.3 0.1 2.9 3 0 0 3 3 3 0 Bacteriophage holin Ribosomal_L31e PF01198.14 KLO09991.1 - 2.5e-36 123.2 2.4 3.4e-36 122.7 1.7 1.2 1 0 0 1 1 1 1 Ribosomal protein L31e CFEM PF05730.6 KLO09992.1 - 4.3e-13 48.8 12.4 8.2e-13 47.9 8.6 1.5 1 0 0 1 1 1 1 CFEM domain Sporozoite_P67 PF05642.6 KLO09992.1 - 1.4 6.6 6.3 1.6 6.4 4.4 1.0 1 0 0 1 1 1 0 Sporozoite P67 surface antigen FYVE PF01363.16 KLO09993.1 - 8.2 6.3 10.9 5.2 7.0 6.0 2.1 1 1 1 2 2 2 0 FYVE zinc finger Ribosomal_L34e PF01199.13 KLO09994.1 - 1.2e-38 131.2 5.0 1.8e-38 130.6 3.5 1.2 1 0 0 1 1 1 1 Ribosomal protein L34e DUF1428 PF07237.6 KLO09994.1 - 0.12 12.2 0.0 0.17 11.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1428) EndIII_4Fe-2S PF10576.4 KLO09994.1 - 0.22 11.7 1.5 2.2 8.6 0.0 2.5 2 0 0 2 2 2 0 Iron-sulfur binding domain of endonuclease III FhuF_C PF11575.3 KLO09994.1 - 0.55 9.9 5.6 4.5 6.9 0.1 2.6 3 0 0 3 3 3 0 FhuF 2Fe-2S C-terminal domain CAP59_mtransfer PF11735.3 KLO09995.1 - 1e-66 224.6 0.0 1.6e-66 224.0 0.0 1.3 1 0 0 1 1 1 1 Cryptococcal mannosyltransferase 1 RCC1_2 PF13540.1 KLO09995.1 - 0.62 9.7 4.0 1.3 8.7 2.8 1.5 1 0 0 1 1 1 0 Regulator of chromosome condensation (RCC1) repeat N2227 PF07942.7 KLO09996.1 - 1.8e-96 322.2 0.0 2.3e-96 321.8 0.0 1.1 1 0 0 1 1 1 1 N2227-like protein Methyltransf_23 PF13489.1 KLO09996.1 - 2.7e-07 30.4 0.0 5.5e-07 29.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KLO09996.1 - 0.00026 21.4 0.0 0.0013 19.1 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 KLO09996.1 - 0.021 15.3 0.0 0.17 12.3 0.0 2.5 3 0 0 3 3 3 0 Methyltransferase domain Methyltransf_26 PF13659.1 KLO09996.1 - 0.026 14.5 0.0 0.054 13.5 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_18 PF12847.2 KLO09996.1 - 0.083 13.4 0.0 0.42 11.2 0.0 2.0 1 1 0 1 1 1 0 Methyltransferase domain Cellulase PF00150.13 KLO09997.1 - 5.1e-14 52.1 0.3 1.4e-09 37.6 0.0 2.6 2 1 0 2 2 2 2 Cellulase (glycosyl hydrolase family 5) Peptidase_C48 PF02902.14 KLO09998.1 - 0.0012 18.4 0.2 0.0039 16.8 0.0 1.9 2 0 0 2 2 2 1 Ulp1 protease family, C-terminal catalytic domain Alpha-amylase PF00128.19 KLO10000.1 - 1.1e-69 235.3 2.6 1.3e-69 235.0 1.8 1.1 1 0 0 1 1 1 1 Alpha amylase, catalytic domain hDGE_amylase PF14701.1 KLO10000.1 - 0.00027 19.9 0.1 0.00039 19.4 0.0 1.1 1 0 0 1 1 1 1 glucanotransferase domain of human glycogen debranching enzyme Glyco_hydro_3 PF00933.16 KLO10001.1 - 8.3e-68 228.5 0.0 1.2e-67 228.0 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain GDPD_2 PF13653.1 KLO10001.1 - 0.16 12.2 0.2 0.54 10.5 0.0 2.0 2 0 0 2 2 2 0 Glycerophosphoryl diester phosphodiesterase family F-box-like PF12937.2 KLO10002.1 - 8e-06 25.4 0.0 2.4e-05 23.9 0.0 1.9 1 0 0 1 1 1 1 F-box-like F-box-like PF12937.2 KLO10003.1 - 2.1e-05 24.1 4.9 5.5e-05 22.8 1.1 2.7 2 1 0 2 2 2 1 F-box-like F-box-like PF12937.2 KLO10006.1 - 1.3e-05 24.7 0.1 3.1e-05 23.6 0.0 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KLO10006.1 - 0.003 17.1 1.6 0.42 10.3 0.3 2.9 2 0 0 2 2 2 2 F-box domain Velvet PF11754.3 KLO10007.1 - 0.14 11.7 0.4 0.21 11.1 0.1 1.4 1 1 0 1 1 1 0 Velvet factor His_Phos_1 PF00300.17 KLO10008.1 - 7.1e-23 81.4 0.0 1.7e-22 80.1 0.0 1.7 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) SNARE_assoc PF09335.6 KLO10009.1 - 1.1e-08 35.3 3.3 1.1e-08 35.3 2.3 2.3 3 0 0 3 3 3 1 SNARE associated Golgi protein Pox_LP_H2 PF03356.10 KLO10009.1 - 0.23 11.1 2.3 5.3 6.6 0.0 2.3 2 0 0 2 2 2 0 Viral late protein H2 Spt5-NGN PF03439.8 KLO10010.1 - 3.3e-07 29.9 0.0 8.8e-07 28.5 0.0 1.7 1 0 0 1 1 1 1 Early transcription elongation factor of RNA pol II, NGN section KOW PF00467.24 KLO10010.1 - 0.0013 18.3 14.8 0.0093 15.6 0.0 4.5 4 0 0 4 4 4 2 KOW motif SNARE_assoc PF09335.6 KLO10012.1 - 1.1e-11 44.9 7.8 1.1e-11 44.9 5.4 2.4 3 0 0 3 3 3 1 SNARE associated Golgi protein DUF1469 PF07332.6 KLO10012.1 - 0.082 12.6 2.8 0.45 10.2 1.5 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF1469) DUF202 PF02656.10 KLO10012.1 - 5.1 7.3 8.9 2.6 8.3 1.2 3.0 3 1 0 3 3 3 0 Domain of unknown function (DUF202) SNARE_assoc PF09335.6 KLO10013.1 - 1.1e-14 54.6 6.0 1.1e-14 54.6 4.2 1.8 1 1 1 2 2 2 1 SNARE associated Golgi protein ETRAMP PF09716.5 KLO10013.1 - 0.079 12.9 1.1 0.24 11.3 0.0 2.2 2 1 0 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) DUF912 PF06024.7 KLO10013.1 - 0.5 10.4 4.9 1.5 8.9 0.8 2.4 2 1 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) SNARE_assoc PF09335.6 KLO10014.1 - 1.1e-14 54.6 7.3 1.1e-14 54.6 5.1 2.1 3 0 0 3 3 3 1 SNARE associated Golgi protein ETRAMP PF09716.5 KLO10014.1 - 0.047 13.6 6.2 0.11 12.4 0.0 2.9 3 0 0 3 3 3 0 Malarial early transcribed membrane protein (ETRAMP) DUF3753 PF12575.3 KLO10014.1 - 0.79 9.5 8.9 2 8.3 0.9 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3753) YwiC PF14256.1 KLO10014.1 - 1.5 8.8 11.9 6.8 6.7 1.1 3.1 2 1 0 2 2 2 0 YwiC-like protein DUF4231 PF14015.1 KLO10014.1 - 1.8 8.5 5.6 18 5.3 2.3 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF4231) DUF2116 PF09889.4 KLO10014.1 - 3.8 7.3 9.0 5.7 6.8 0.2 2.8 3 0 0 3 3 3 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) DUF4179 PF13786.1 KLO10014.1 - 5.2 7.3 7.4 0.67 10.2 0.1 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4179) Herpes_US9 PF06072.6 KLO10014.1 - 6.8 6.6 8.3 11 5.8 1.6 2.9 2 0 0 2 2 2 0 Alphaherpesvirus tegument protein US9 HemY_N PF07219.8 KLO10014.1 - 7.4 6.1 7.3 7.2 6.2 0.1 2.5 2 0 0 2 2 2 0 HemY protein N-terminus Sigma_reg_N PF13800.1 KLO10014.1 - 8.8 6.4 9.6 13 5.9 2.1 2.4 2 0 0 2 2 2 0 Sigma factor regulator N-terminal SNARE_assoc PF09335.6 KLO10015.1 - 1.7e-14 54.0 9.7 1.7e-14 54.0 6.7 1.9 3 0 0 3 3 3 1 SNARE associated Golgi protein SNARE_assoc PF09335.6 KLO10016.1 - 1e-14 54.7 10.2 7.6e-14 51.9 5.9 2.3 2 0 0 2 2 2 1 SNARE associated Golgi protein DUF2053 PF09767.4 KLO10016.1 - 0.076 13.0 0.2 0.16 11.9 0.1 1.5 1 0 0 1 1 1 0 Predicted membrane protein (DUF2053) DUF3611 PF12263.3 KLO10016.1 - 3.1 7.1 6.5 0.32 10.3 0.1 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3611) Lact-deh-memb PF09330.6 KLO10018.1 - 0.028 13.8 0.0 0.039 13.3 0.0 1.1 1 0 0 1 1 1 0 D-lactate dehydrogenase, membrane binding Plasmid_stabil PF05016.9 KLO10018.1 - 0.093 13.1 0.1 0.15 12.5 0.1 1.4 1 0 0 1 1 1 0 Plasmid stabilisation system protein SNARE_assoc PF09335.6 KLO10021.1 - 7.7e-16 58.4 14.5 8.2e-16 58.3 6.7 2.4 2 1 0 2 2 2 1 SNARE associated Golgi protein DUF3816 PF12822.2 KLO10021.1 - 4 7.3 22.2 32 4.3 15.4 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF3816) F-box-like PF12937.2 KLO10023.1 - 0.011 15.4 0.3 0.028 14.1 0.2 1.7 1 0 0 1 1 1 0 F-box-like F-box-like PF12937.2 KLO10024.1 - 9.1e-06 25.3 0.0 2.1e-05 24.1 0.0 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KLO10024.1 - 1.6e-05 24.4 0.2 6.1e-05 22.5 0.2 2.1 1 0 0 1 1 1 1 F-box domain LRR_8 PF13855.1 KLO10024.1 - 5.6 6.8 8.7 4.2 7.1 0.1 3.6 4 0 0 4 4 4 0 Leucine rich repeat F-box-like PF12937.2 KLO10025.1 - 0.00027 20.6 0.4 0.0016 18.0 0.2 2.4 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 KLO10025.1 - 0.0053 16.3 1.0 0.0053 16.3 0.7 2.2 2 0 0 2 2 2 1 F-box domain LRR_8 PF13855.1 KLO10025.1 - 0.019 14.7 3.2 0.054 13.2 0.0 3.3 3 1 1 4 4 4 0 Leucine rich repeat HAD_2 PF13419.1 KLO10028.1 - 1.8e-21 77.1 0.1 2.3e-21 76.7 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 KLO10028.1 - 2e-06 27.3 0.0 3.8e-06 26.4 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.21 KLO10028.1 - 3.1e-06 27.7 0.0 7.2e-06 26.5 0.0 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase MULE PF10551.4 KLO10035.1 - 0.00013 22.0 0.0 0.00032 20.7 0.0 1.7 1 0 0 1 1 1 1 MULE transposase domain SWIM PF04434.12 KLO10035.1 - 0.023 14.1 1.3 0.054 12.9 0.9 1.6 1 0 0 1 1 1 0 SWIM zinc finger Tet_JBP PF12851.2 KLO10039.1 - 8.4e-13 47.9 0.0 1e-12 47.7 0.0 1.1 1 0 0 1 1 1 1 Oxygenase domain of the 2OGFeDO superfamily HLH PF00010.21 KLO10041.1 - 2.1e-19 68.9 0.6 1.3e-18 66.4 0.0 2.5 2 1 1 3 3 3 1 Helix-loop-helix DNA-binding domain STAS_2 PF13466.1 KLO10043.1 - 0.092 12.7 0.1 0.15 12.1 0.1 1.4 1 0 0 1 1 1 0 STAS domain Cation_efflux PF01545.16 KLO10044.1 - 0.00068 18.7 0.1 0.00095 18.3 0.1 1.2 1 0 0 1 1 1 1 Cation efflux family Transglut_core3 PF13471.1 KLO10045.1 - 0.1 12.4 2.5 0.09 12.5 0.5 1.7 2 0 0 2 2 2 0 Transglutaminase-like superfamily PAP2 PF01569.16 KLO10046.1 - 2.9e-16 59.3 9.1 2.9e-16 59.3 6.3 2.0 2 1 0 2 2 2 1 PAP2 superfamily Abhydrolase_6 PF12697.2 KLO10048.1 - 1.8e-16 60.6 0.1 2.5e-16 60.2 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KLO10048.1 - 6.9e-06 25.8 0.0 1.7e-05 24.6 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KLO10048.1 - 0.00087 18.9 0.1 0.097 12.2 0.1 3.0 2 1 0 2 2 2 1 alpha/beta hydrolase fold Chlorophyllase2 PF12740.2 KLO10048.1 - 0.17 10.7 0.0 0.24 10.2 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase enzyme TraS PF10624.4 KLO10049.1 - 0.12 11.9 0.0 0.19 11.3 0.0 1.2 1 0 0 1 1 1 0 Plasmid conjugative transfer entry exclusion protein TraS Abhydrolase_6 PF12697.2 KLO10051.1 - 1.4e-09 38.1 0.0 3.1e-09 37.0 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KLO10051.1 - 0.00071 19.3 0.0 0.0016 18.2 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family APH PF01636.18 KLO10052.1 - 3e-17 63.1 0.0 4.8e-17 62.4 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 KLO10052.1 - 0.042 13.4 0.0 0.078 12.5 0.0 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase HLH PF00010.21 KLO10053.1 - 1.2e-08 34.5 0.6 2.9e-08 33.2 0.4 1.7 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain WD40 PF00400.27 KLO10054.1 - 1.2e-35 120.0 11.5 3.8e-08 32.8 0.1 6.6 6 1 0 6 6 6 6 WD domain, G-beta repeat Rav1p_C PF12234.3 KLO10054.1 - 0.034 12.3 0.1 0.055 11.6 0.1 1.2 1 0 0 1 1 1 0 RAVE protein 1 C terminal Legionella_OMP PF05150.7 KLO10054.1 - 0.042 12.9 0.9 0.063 12.3 0.6 1.2 1 0 0 1 1 1 0 Legionella pneumophila major outer membrane protein precursor Nucleoporin_N PF08801.6 KLO10054.1 - 0.12 11.0 0.0 0.12 11.0 0.0 1.9 2 1 0 2 2 2 0 Nup133 N terminal like SseC PF04888.7 KLO10055.1 - 0.87 8.8 5.7 2.5 7.3 0.0 2.4 3 0 0 3 3 3 0 Secretion system effector C (SseC) like family Fungal_trans PF04082.13 KLO10056.1 - 1.9e-15 56.4 0.1 3.6e-15 55.5 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KLO10056.1 - 0.00061 19.6 14.8 0.0013 18.6 10.2 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain 2-Hacid_dh_C PF02826.14 KLO10057.1 - 3.3e-38 130.6 0.0 5e-36 123.4 0.0 2.9 2 1 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 KLO10057.1 - 2.5e-25 88.5 0.0 2.9e-25 88.2 0.0 1.0 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 KLO10057.1 - 0.00023 21.0 0.0 0.001 18.9 0.0 1.9 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.12 KLO10057.1 - 0.017 15.5 0.0 0.042 14.2 0.0 1.7 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent zf-RING_2 PF13639.1 KLO10058.1 - 2.6e-07 30.3 7.9 4.8e-07 29.4 5.5 1.5 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 KLO10058.1 - 5e-06 26.5 3.6 1.1e-05 25.4 2.5 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger FANCL_C PF11793.3 KLO10058.1 - 0.00032 20.5 6.0 0.00066 19.5 4.1 1.5 1 0 0 1 1 1 1 FANCL C-terminal domain zf-Apc11 PF12861.2 KLO10058.1 - 0.0018 18.0 2.7 0.0038 17.0 1.8 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger RINGv PF12906.2 KLO10058.1 - 0.02 14.9 7.6 0.042 13.8 5.3 1.6 1 0 0 1 1 1 0 RING-variant domain C1_1 PF00130.17 KLO10058.1 - 0.031 13.9 6.4 0.01 15.5 2.5 1.6 1 1 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-C3HC4 PF00097.20 KLO10058.1 - 0.18 11.5 8.5 0.35 10.5 5.9 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Sporozoite_P67 PF05642.6 KLO10058.1 - 0.5 8.1 0.1 0.83 7.4 0.0 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen zf-C3HC4_2 PF13923.1 KLO10058.1 - 1.2 9.2 8.6 2.3 8.2 6.0 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING-like PF08746.6 KLO10058.1 - 1.6 8.7 6.7 3.2 7.8 4.6 1.5 1 0 0 1 1 1 0 RING-like domain zf-C3HC4_3 PF13920.1 KLO10058.1 - 4.8 6.9 6.2 10 5.8 4.3 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) TPR_11 PF13414.1 KLO10059.1 - 7.1e-06 25.5 0.0 1.5e-05 24.5 0.0 1.5 1 0 0 1 1 1 1 TPR repeat Tbf5 PF06331.7 KLO10062.1 - 0.0095 15.6 0.0 0.017 14.8 0.0 1.4 1 0 0 1 1 1 1 Transcription factor TFIIH complex subunit Tfb5 Transp_cyt_pur PF02133.10 KLO10063.1 - 5.9e-36 123.9 37.5 9.2e-36 123.3 26.0 1.2 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin DUF2235 PF09994.4 KLO10064.1 - 3.6e-74 249.6 0.0 5.3e-74 249.0 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) Abhydrolase_5 PF12695.2 KLO10064.1 - 0.047 13.4 0.0 0.082 12.6 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family Peptidase_S10 PF00450.17 KLO10065.1 - 7.1e-112 374.6 0.0 9.4e-112 374.2 0.0 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase Abhydrolase_6 PF12697.2 KLO10065.1 - 2e-05 24.5 0.0 0.00012 22.0 0.0 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S10 PF00450.17 KLO10066.1 - 1.3e-103 347.4 0.0 1.6e-103 347.0 0.0 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase Abhydrolase_6 PF12697.2 KLO10066.1 - 0.00014 21.8 0.0 0.11 12.3 0.0 2.2 2 0 0 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KLO10066.1 - 0.017 14.8 0.0 0.077 12.7 0.0 2.0 1 1 0 1 1 1 0 Alpha/beta hydrolase family GST_N_3 PF13417.1 KLO10067.1 - 6.8e-12 45.4 0.1 1.2e-11 44.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 KLO10067.1 - 5.8e-09 35.7 0.0 1.4e-08 34.5 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 KLO10067.1 - 1.3e-06 28.2 0.0 2.3e-06 27.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 KLO10067.1 - 8.6e-06 25.6 0.0 3.1e-05 23.8 0.0 2.0 2 1 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 KLO10067.1 - 0.00076 19.6 0.0 0.002 18.2 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 KLO10067.1 - 0.0015 18.9 0.0 0.0024 18.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Glutaredoxin PF00462.19 KLO10067.1 - 0.004 17.1 0.0 0.0071 16.3 0.0 1.4 1 0 0 1 1 1 1 Glutaredoxin adh_short PF00106.20 KLO10068.1 - 2.6e-32 112.0 2.9 3.2e-32 111.7 2.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KLO10068.1 - 5.5e-19 68.8 0.0 7.3e-19 68.4 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KLO10068.1 - 2.9e-10 40.0 1.7 3.9e-10 39.6 1.2 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 KLO10068.1 - 0.008 15.6 0.4 0.0095 15.3 0.3 1.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Ribul_P_3_epim PF00834.14 KLO10068.1 - 0.049 12.7 0.0 0.14 11.2 0.0 1.7 2 0 0 2 2 2 0 Ribulose-phosphate 3 epimerase family 3HCDH_N PF02737.13 KLO10068.1 - 0.11 12.1 0.2 0.16 11.5 0.1 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain WD40 PF00400.27 KLO10069.1 - 4.2e-36 121.5 33.5 2.7e-08 33.4 1.1 10.7 9 1 0 9 9 9 8 WD domain, G-beta repeat PD40 PF07676.7 KLO10069.1 - 5.8e-08 32.2 2.4 0.68 9.6 0.0 5.4 5 0 0 5 5 5 3 WD40-like Beta Propeller Repeat NACHT PF05729.7 KLO10069.1 - 2.9e-07 30.2 0.0 6.4e-07 29.1 0.0 1.6 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 KLO10069.1 - 0.0006 19.8 0.0 0.0022 17.9 0.0 2.1 1 1 0 1 1 1 1 AAA ATPase domain Nup160 PF11715.3 KLO10069.1 - 0.0015 16.8 0.1 1.6 6.7 0.0 3.3 3 1 0 3 3 3 2 Nucleoporin Nup120/160 Zeta_toxin PF06414.7 KLO10069.1 - 0.0044 16.1 0.0 0.0083 15.2 0.0 1.3 1 0 0 1 1 1 1 Zeta toxin AAA_22 PF13401.1 KLO10069.1 - 0.0079 16.3 0.0 0.027 14.6 0.0 1.9 2 0 0 2 2 2 1 AAA domain DUF2075 PF09848.4 KLO10069.1 - 0.031 13.2 0.0 0.059 12.3 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA PF00004.24 KLO10069.1 - 0.077 13.1 0.0 0.38 10.9 0.0 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Gp-FAR-1 PF05823.7 KLO10069.1 - 0.15 11.9 0.5 0.29 11.0 0.4 1.3 1 0 0 1 1 1 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) Proteasome_A_N PF10584.4 KLO10069.1 - 0.19 11.1 0.1 77 2.7 0.0 3.6 3 0 0 3 3 3 0 Proteasome subunit A N-terminal signature NB-ARC PF00931.17 KLO10069.1 - 0.2 10.4 0.0 0.41 9.4 0.0 1.5 1 0 0 1 1 1 0 NB-ARC domain AAA_19 PF13245.1 KLO10069.1 - 0.22 11.2 0.0 0.6 9.9 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain WD40 PF00400.27 KLO10072.1 - 4.3e-16 58.1 14.2 1.1e-05 25.1 0.5 6.1 6 0 0 6 6 6 3 WD domain, G-beta repeat AAA_16 PF13191.1 KLO10072.1 - 2.3e-07 30.9 0.0 4.7e-07 29.9 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain PD40 PF07676.7 KLO10072.1 - 1.1e-06 28.1 0.2 0.45 10.2 0.0 3.8 3 0 0 3 3 3 2 WD40-like Beta Propeller Repeat AAA PF00004.24 KLO10072.1 - 1.5e-05 25.1 0.0 0.00014 22.0 0.0 2.4 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) NACHT PF05729.7 KLO10072.1 - 2.4e-05 24.0 0.2 0.00014 21.5 0.1 2.0 1 1 0 1 1 1 1 NACHT domain AAA_19 PF13245.1 KLO10072.1 - 0.0005 19.7 0.0 0.026 14.2 0.0 2.5 2 0 0 2 2 2 1 Part of AAA domain AAA_22 PF13401.1 KLO10072.1 - 0.0043 17.1 0.0 0.014 15.5 0.0 1.8 1 0 0 1 1 1 1 AAA domain KAP_NTPase PF07693.9 KLO10072.1 - 0.045 12.7 0.8 3.5 6.5 0.0 2.2 1 1 0 2 2 2 0 KAP family P-loop domain AAA_11 PF13086.1 KLO10072.1 - 0.051 13.1 0.0 0.13 11.8 0.0 1.7 2 0 0 2 2 1 0 AAA domain Arch_ATPase PF01637.13 KLO10072.1 - 0.052 13.2 0.0 0.12 12.0 0.0 1.6 1 0 0 1 1 1 0 Archaeal ATPase Gmad1 PF10647.4 KLO10072.1 - 0.055 12.8 0.1 0.3 10.4 0.0 1.9 1 1 0 1 1 1 0 Lipoprotein LpqB beta-propeller domain AAA_33 PF13671.1 KLO10072.1 - 0.055 13.3 0.0 0.12 12.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain Nbas_N PF15492.1 KLO10072.1 - 0.08 12.0 0.0 2.1 7.3 0.0 2.2 2 0 0 2 2 2 0 Neuroblastoma-amplified sequence, N terminal TruB_C PF09142.6 KLO10072.1 - 0.084 12.5 0.1 32 4.2 0.0 3.7 3 1 1 4 4 4 0 tRNA Pseudouridine synthase II, C terminal DUF2075 PF09848.4 KLO10072.1 - 0.095 11.6 0.0 0.19 10.6 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) NTPase_1 PF03266.10 KLO10072.1 - 0.12 12.0 0.0 0.27 10.9 0.0 1.5 1 0 0 1 1 1 0 NTPase RNA_helicase PF00910.17 KLO10072.1 - 0.17 12.0 0.0 0.42 10.8 0.0 1.7 1 0 0 1 1 1 0 RNA helicase Phage_integrase PF00589.17 KLO10084.1 - 0.0024 17.5 0.0 0.026 14.2 0.0 2.2 1 1 0 1 1 1 1 Phage integrase family Peptidase_S10 PF00450.17 KLO10086.1 - 7.4e-66 223.0 0.0 2.9e-65 221.0 0.0 1.8 1 1 0 1 1 1 1 Serine carboxypeptidase Methyltransf_2 PF00891.13 KLO10090.1 - 3e-28 98.6 0.0 6.3e-28 97.5 0.0 1.5 1 1 0 1 1 1 1 O-methyltransferase Methyltransf_18 PF12847.2 KLO10090.1 - 1.7e-05 25.3 0.1 3.8e-05 24.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KLO10090.1 - 9.8e-05 21.7 0.0 0.00018 20.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Dimerisation PF08100.6 KLO10090.1 - 0.00037 20.2 0.0 0.0012 18.6 0.0 1.9 1 0 0 1 1 1 1 Dimerisation domain Methyltransf_23 PF13489.1 KLO10090.1 - 0.00097 18.8 0.0 0.0092 15.7 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain ECH PF00378.15 KLO10090.1 - 0.0025 16.9 0.0 0.0041 16.2 0.0 1.3 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family Methyltransf_12 PF08242.7 KLO10090.1 - 0.0029 18.0 0.0 0.0064 16.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain RrnaAD PF00398.15 KLO10090.1 - 0.047 12.7 0.0 0.079 11.9 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Methyltransf_31 PF13847.1 KLO10090.1 - 0.059 12.9 0.0 0.1 12.1 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain RPA_C PF08784.6 KLO10090.1 - 0.13 12.7 0.0 1.1 9.7 0.0 2.2 1 1 1 2 2 2 0 Replication protein A C terminal Erp_C PF06780.6 KLO10092.1 - 0.11 12.2 0.6 0.29 10.9 0.1 1.8 2 0 0 2 2 2 0 Erp protein C-terminus Complex1_51K PF01512.12 KLO10093.1 - 2.6e-48 163.5 0.0 3.8e-48 163.0 0.0 1.3 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase 51 Kd subunit NADH_4Fe-4S PF10589.4 KLO10093.1 - 6e-22 76.5 2.0 4.8e-21 73.6 0.5 2.3 2 0 0 2 2 2 1 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region SLBB PF10531.4 KLO10093.1 - 7.1e-09 35.4 0.0 2.1e-08 33.9 0.0 1.9 1 0 0 1 1 1 1 SLBB domain SAM_2 PF07647.12 KLO10094.1 - 8.2e-11 41.6 0.0 2.6e-10 39.9 0.0 1.9 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.25 KLO10094.1 - 3.3e-09 36.7 0.1 9.7e-09 35.2 0.0 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Aldolase_II PF00596.16 KLO10095.1 - 2.4e-25 89.2 0.0 3.1e-25 88.8 0.0 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain F-box-like PF12937.2 KLO10098.1 - 0.0014 18.2 0.0 0.0038 16.9 0.0 1.7 1 0 0 1 1 1 1 F-box-like EAP30 PF04157.11 KLO10098.1 - 0.044 12.9 0.1 0.068 12.3 0.1 1.2 1 0 0 1 1 1 0 EAP30/Vps36 family F-box PF00646.28 KLO10098.1 - 0.069 12.8 0.0 0.17 11.5 0.0 1.7 1 0 0 1 1 1 0 F-box domain Glyco_hydro_15 PF00723.16 KLO10099.1 - 2.5e-54 184.5 0.0 3.9e-54 183.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 15 DSPc PF00782.15 KLO10100.1 - 1.4e-27 95.8 0.0 2e-27 95.3 0.0 1.1 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 KLO10100.1 - 0.004 16.5 0.0 0.0056 16.0 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.1 KLO10100.1 - 0.11 12.5 0.0 0.17 11.9 0.0 1.2 1 0 0 1 1 1 0 Inositol hexakisphosphate DUF1020 PF06255.8 KLO10103.1 - 0.098 11.8 0.0 0.15 11.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1020) Gly_transf_sug PF04488.10 KLO10104.1 - 1.1e-07 32.1 0.0 2.1e-07 31.2 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Caps_synth PF05704.7 KLO10104.1 - 0.00034 19.8 0.2 0.00053 19.2 0.2 1.2 1 0 0 1 1 1 1 Capsular polysaccharide synthesis protein TcdA_TcdB PF12919.2 KLO10104.1 - 0.14 10.6 0.1 0.2 10.0 0.1 1.1 1 0 0 1 1 1 0 TcdA/TcdB catalytic glycosyltransferase domain Glyco_transf_8 PF01501.15 KLO10105.1 - 3.7e-25 88.6 0.0 6.1e-25 87.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 8 Glyco_transf_8 PF01501.15 KLO10106.1 - 3.7e-24 85.4 0.0 7.2e-24 84.4 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 8 APH PF01636.18 KLO10107.1 - 6.2e-07 29.3 0.0 1.2e-06 28.4 0.0 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 KLO10107.1 - 0.14 11.6 0.0 0.25 10.8 0.0 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase p450 PF00067.17 KLO10108.1 - 2.9e-70 237.0 0.0 3.6e-70 236.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 NACHT PF05729.7 KLO10109.1 - 2.1e-12 47.0 0.0 3.6e-12 46.2 0.0 1.3 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 KLO10109.1 - 8.4e-09 35.6 0.0 1.3e-08 35.0 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 KLO10109.1 - 1.7e-08 34.6 0.0 3.6e-08 33.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.1 KLO10109.1 - 3.3e-07 29.9 0.0 6e-07 29.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.1 KLO10109.1 - 1.4e-06 28.1 0.0 0.0029 17.4 0.0 2.2 1 1 1 2 2 2 2 AAA domain AAA_17 PF13207.1 KLO10109.1 - 9.4e-05 23.2 0.0 0.00021 22.0 0.0 1.8 1 1 0 1 1 1 1 AAA domain FtsK_SpoIIIE PF01580.13 KLO10109.1 - 0.0001 21.8 0.0 0.00031 20.2 0.0 1.7 1 1 0 1 1 1 1 FtsK/SpoIIIE family AAA PF00004.24 KLO10109.1 - 0.00014 22.1 0.0 0.00037 20.6 0.0 1.8 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_10 PF12846.2 KLO10109.1 - 0.00018 21.0 0.0 0.00042 19.8 0.0 1.6 1 1 0 1 1 1 1 AAA-like domain NB-ARC PF00931.17 KLO10109.1 - 0.00024 20.0 0.0 0.00033 19.6 0.0 1.1 1 0 0 1 1 1 1 NB-ARC domain AAA_33 PF13671.1 KLO10109.1 - 0.00094 19.0 0.0 0.0015 18.4 0.0 1.5 1 1 0 1 1 1 1 AAA domain ABC_tran PF00005.22 KLO10109.1 - 0.0015 18.8 0.0 0.003 17.8 0.0 1.6 1 0 0 1 1 1 1 ABC transporter RNA_helicase PF00910.17 KLO10109.1 - 0.0017 18.4 0.0 0.003 17.6 0.0 1.6 1 0 0 1 1 1 1 RNA helicase AAA_18 PF13238.1 KLO10109.1 - 0.0019 18.4 0.0 0.0051 17.1 0.0 1.8 1 1 0 1 1 1 1 AAA domain Arch_ATPase PF01637.13 KLO10109.1 - 0.0028 17.3 0.0 0.0039 16.9 0.0 1.2 1 0 0 1 1 1 1 Archaeal ATPase AAA_19 PF13245.1 KLO10109.1 - 0.0064 16.2 0.0 0.013 15.2 0.0 1.5 1 0 0 1 1 1 1 Part of AAA domain NTPase_1 PF03266.10 KLO10109.1 - 0.0088 15.7 0.0 0.012 15.2 0.0 1.2 1 0 0 1 1 1 1 NTPase Zeta_toxin PF06414.7 KLO10109.1 - 0.009 15.1 0.0 0.016 14.3 0.0 1.3 1 0 0 1 1 1 1 Zeta toxin DUF2075 PF09848.4 KLO10109.1 - 0.0094 14.9 0.0 0.012 14.6 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) TIP49 PF06068.8 KLO10109.1 - 0.0097 14.6 0.0 0.014 14.1 0.0 1.1 1 0 0 1 1 1 1 TIP49 C-terminus APS_kinase PF01583.15 KLO10109.1 - 0.015 14.9 0.0 0.026 14.1 0.0 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase Viral_helicase1 PF01443.13 KLO10109.1 - 0.021 14.3 0.0 0.031 13.8 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase MobB PF03205.9 KLO10109.1 - 0.024 14.3 0.0 0.041 13.5 0.0 1.3 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B IstB_IS21 PF01695.12 KLO10109.1 - 0.031 13.7 0.1 0.052 12.9 0.0 1.5 1 1 0 1 1 1 0 IstB-like ATP binding protein ArgK PF03308.11 KLO10109.1 - 0.034 12.9 0.0 0.053 12.2 0.0 1.2 1 0 0 1 1 1 0 ArgK protein MMR_HSR1 PF01926.18 KLO10109.1 - 0.045 13.7 0.0 0.07 13.0 0.0 1.5 1 1 0 1 1 1 0 50S ribosome-binding GTPase Parvo_NS1 PF01057.12 KLO10109.1 - 0.045 12.6 0.1 0.075 11.8 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_5 PF07728.9 KLO10109.1 - 0.045 13.4 0.0 0.45 10.2 0.0 2.3 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) DDE_Tnp_1_assoc PF13808.1 KLO10109.1 - 0.052 13.2 0.5 4.7 6.9 0.0 2.6 2 1 0 2 2 2 0 DDE_Tnp_1-associated cobW PF02492.14 KLO10109.1 - 0.073 12.5 0.0 0.34 10.3 0.0 2.0 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain DUF815 PF05673.8 KLO10109.1 - 0.091 11.6 0.0 0.16 10.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) DUF87 PF01935.12 KLO10109.1 - 0.12 12.1 0.0 0.31 10.8 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function DUF87 PPV_E1_C PF00519.12 KLO10109.1 - 0.14 10.7 0.0 0.81 8.2 0.0 2.0 2 0 0 2 2 2 0 Papillomavirus helicase ADK PF00406.17 KLO10109.1 - 0.14 11.9 0.0 0.26 11.1 0.0 1.4 1 0 0 1 1 1 0 Adenylate kinase AAA_PrkA PF08298.6 KLO10109.1 - 0.15 10.7 0.0 0.2 10.2 0.0 1.1 1 0 0 1 1 1 0 PrkA AAA domain Mg_chelatase PF01078.16 KLO10109.1 - 0.15 11.2 0.0 0.26 10.4 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI KTI12 PF08433.5 KLO10109.1 - 0.15 11.2 0.0 0.21 10.7 0.0 1.2 1 0 0 1 1 1 0 Chromatin associated protein KTI12 AAA_24 PF13479.1 KLO10109.1 - 0.15 11.5 0.1 1 8.8 0.0 2.1 2 0 0 2 2 2 0 AAA domain GTP_EFTU PF00009.22 KLO10110.1 - 7.4e-62 208.1 1.1 1.9e-61 206.8 0.1 1.9 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.13 KLO10110.1 - 6.8e-39 132.1 0.0 2.4e-38 130.3 0.0 2.0 2 0 0 2 2 2 1 Elongation factor G, domain IV EFG_C PF00679.19 KLO10110.1 - 3.5e-21 74.8 0.0 8.3e-21 73.6 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.1 KLO10110.1 - 2.5e-13 49.6 0.0 6.5e-13 48.3 0.0 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II GTP_EFTU_D2 PF03144.20 KLO10110.1 - 8.6e-09 35.3 0.0 4e-08 33.2 0.0 2.2 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 KLO10110.1 - 6.4e-06 26.1 0.2 1.6e-05 24.8 0.1 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase Glyco_transf_8 PF01501.15 KLO10111.1 - 2.7e-24 85.8 0.0 6e-24 84.7 0.0 1.5 1 1 0 1 1 1 1 Glycosyl transferase family 8 MRP-S32 PF10210.4 KLO10111.1 - 0.14 12.4 0.0 0.39 11.0 0.0 1.7 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S32 GTP_EFTU PF00009.22 KLO10112.1 - 6e-61 205.1 0.2 9.2e-61 204.5 0.2 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.13 KLO10112.1 - 4.1e-37 126.4 0.0 2.9e-36 123.6 0.0 2.3 1 1 1 2 2 2 1 Elongation factor G, domain IV EFG_C PF00679.19 KLO10112.1 - 6.2e-20 70.8 0.0 1.8e-19 69.3 0.0 1.9 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.1 KLO10112.1 - 1.9e-11 43.6 0.0 4.7e-11 42.3 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II GTP_EFTU_D2 PF03144.20 KLO10112.1 - 6.2e-08 32.6 0.0 1.9e-07 31.1 0.0 1.9 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 KLO10112.1 - 1.6e-05 24.8 0.1 4.1e-05 23.5 0.1 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.5 KLO10112.1 - 0.0095 15.1 0.1 0.02 14.0 0.1 1.5 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Miro PF08477.8 KLO10112.1 - 0.045 14.2 0.1 0.1 13.0 0.1 1.6 1 0 0 1 1 1 0 Miro-like protein WD40 PF00400.27 KLO10113.1 - 2.3e-58 192.1 9.3 1.5e-11 43.6 0.1 7.3 7 0 0 7 7 7 6 WD domain, G-beta repeat LisH PF08513.6 KLO10113.1 - 1.1e-07 31.4 0.0 1.9e-07 30.6 0.0 1.4 1 0 0 1 1 1 1 LisH eIF2A PF08662.6 KLO10113.1 - 1.1e-05 25.2 0.0 0.00061 19.5 0.0 2.8 2 2 1 3 3 3 1 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 KLO10113.1 - 0.00053 18.2 0.3 0.11 10.5 0.1 2.3 2 0 0 2 2 2 2 Nucleoporin Nup120/160 Nbas_N PF15492.1 KLO10113.1 - 0.0012 17.9 0.3 0.55 9.2 0.0 3.6 2 2 2 4 4 4 1 Neuroblastoma-amplified sequence, N terminal Nucleoporin_N PF08801.6 KLO10113.1 - 0.009 14.7 4.1 0.2 10.3 0.1 3.7 3 2 0 4 4 4 1 Nup133 N terminal like Bax1-I PF01027.15 KLO10115.1 - 4.7e-35 121.0 12.7 5e-35 120.9 7.8 1.7 2 0 0 2 2 2 1 Inhibitor of apoptosis-promoting Bax1 DUF4079 PF13301.1 KLO10115.1 - 1.9 8.4 9.2 82 3.1 3.9 3.6 1 1 1 3 3 3 0 Protein of unknown function (DUF4079) Podoplanin PF05808.6 KLO10116.1 - 0.023 14.2 0.9 0.023 14.2 0.6 1.8 2 0 0 2 2 2 0 Podoplanin DUF912 PF06024.7 KLO10116.1 - 0.024 14.7 0.0 0.051 13.6 0.0 1.5 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Rifin_STEVOR PF02009.11 KLO10116.1 - 0.038 13.6 0.0 0.053 13.1 0.0 1.2 1 0 0 1 1 1 0 Rifin/stevor family TMEM154 PF15102.1 KLO10116.1 - 0.046 13.4 0.1 0.091 12.4 0.0 1.4 1 0 0 1 1 1 0 TMEM154 protein family EVI2A PF05399.6 KLO10116.1 - 0.057 12.6 3.9 0.11 11.7 2.7 1.5 1 0 0 1 1 1 0 Ectropic viral integration site 2A protein (EVI2A) DUF1517 PF07466.6 KLO10116.1 - 0.11 11.5 6.3 0.018 14.0 1.3 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1517) Abhydrolase_6 PF12697.2 KLO10118.1 - 7.4e-17 61.9 0.2 1.9e-10 41.0 0.0 2.5 2 0 0 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KLO10118.1 - 1.7e-07 31.0 0.1 0.014 15.1 0.0 3.1 2 1 0 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KLO10118.1 - 0.00031 20.3 0.0 0.00064 19.3 0.0 1.6 1 0 0 1 1 1 1 alpha/beta hydrolase fold Ndr PF03096.9 KLO10118.1 - 0.35 9.2 0.0 0.63 8.4 0.0 1.3 1 0 0 1 1 1 0 Ndr family zf-Tim10_DDP PF02953.10 KLO10119.1 - 4.5e-21 73.9 0.5 5.8e-21 73.5 0.3 1.2 1 0 0 1 1 1 1 Tim10/DDP family zinc finger Retro_M PF02813.9 KLO10119.1 - 0.061 13.4 0.0 0.079 13.1 0.0 1.2 1 0 0 1 1 1 0 Retroviral M domain Myotub-related PF06602.9 KLO10119.1 - 0.096 11.4 0.0 0.099 11.3 0.0 1.0 1 0 0 1 1 1 0 Myotubularin-like phosphatase domain Acyltransferase PF01553.16 KLO10120.1 - 5.7e-23 80.8 0.0 1e-22 80.0 0.0 1.4 1 0 0 1 1 1 1 Acyltransferase DUF1348 PF07080.6 KLO10121.1 - 1.8e-50 170.4 6.4 2.1e-50 170.2 4.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1348) DUF4440 PF14534.1 KLO10121.1 - 0.00013 22.1 0.1 0.00018 21.6 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4440) SnoaL_2 PF12680.2 KLO10121.1 - 0.00016 21.9 0.3 0.00023 21.5 0.2 1.5 1 1 0 1 1 1 1 SnoaL-like domain NDUF_B6 PF09782.4 KLO10121.1 - 0.24 11.2 3.1 0.13 12.0 0.6 1.6 1 1 1 2 2 2 0 NADH:ubiquinone oxidoreductase, NDUFB6/B17 subunit SGL PF08450.7 KLO10123.1 - 3.3e-26 92.1 0.0 8.7e-26 90.7 0.0 1.7 1 1 0 1 1 1 1 SMP-30/Gluconolaconase/LRE-like region Str_synth PF03088.11 KLO10123.1 - 0.0066 16.4 0.0 0.065 13.2 0.0 2.2 2 0 0 2 2 2 1 Strictosidine synthase Arylesterase PF01731.15 KLO10123.1 - 0.01 15.7 0.0 0.2 11.6 0.0 2.5 2 0 0 2 2 2 0 Arylesterase SBBP PF06739.6 KLO10123.1 - 0.12 12.2 1.0 6.6 6.6 0.0 2.8 2 0 0 2 2 2 0 Beta-propeller repeat NHL PF01436.16 KLO10123.1 - 0.16 11.9 0.5 5.6 7.1 0.1 2.9 2 0 0 2 2 2 0 NHL repeat SLD3 PF08639.5 KLO10124.1 - 5.1e-14 51.8 6.2 5.1e-14 51.8 4.3 1.8 2 0 0 2 2 2 1 DNA replication regulator SLD3 AlaDh_PNT_N PF05222.10 KLO10126.1 - 4.6e-28 97.9 0.0 6.7e-28 97.3 0.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, N-terminal domain AlaDh_PNT_C PF01262.16 KLO10126.1 - 2.7e-11 43.3 0.0 1.2e-10 41.1 0.0 1.9 1 1 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain adh_short PF00106.20 KLO10127.1 - 1.2e-19 70.8 0.0 1.5e-19 70.4 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KLO10127.1 - 1.5e-05 24.7 0.4 5.1e-05 23.0 0.3 1.8 1 1 0 1 1 1 1 KR domain Saccharop_dh PF03435.13 KLO10127.1 - 0.0026 16.8 0.2 0.0037 16.2 0.1 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase Epimerase PF01370.16 KLO10127.1 - 0.0074 15.7 0.0 0.029 13.8 0.0 1.7 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family Shikimate_DH PF01488.15 KLO10127.1 - 0.0077 16.3 0.1 0.016 15.3 0.0 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Eno-Rase_NADH_b PF12242.3 KLO10127.1 - 0.011 15.4 0.2 0.024 14.4 0.1 1.5 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Polysacc_synt_2 PF02719.10 KLO10127.1 - 0.042 12.7 0.0 0.058 12.2 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.1 KLO10127.1 - 0.087 12.8 0.1 0.14 12.1 0.1 1.3 1 0 0 1 1 1 0 NADH(P)-binding Ras PF00071.17 KLO10129.1 - 9.5e-54 181.1 0.0 1.1e-53 180.9 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KLO10129.1 - 2.6e-15 56.9 0.0 3.9e-15 56.4 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KLO10129.1 - 1.2e-07 31.1 0.0 1.4e-07 30.9 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 KLO10129.1 - 0.00032 20.1 0.0 0.0031 16.9 0.0 1.9 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain FG-GAP PF01839.18 KLO10130.1 - 0.059 13.0 5.7 1.4 8.7 0.9 2.9 2 0 0 2 2 2 0 FG-GAP repeat VCBS PF13517.1 KLO10130.1 - 2.1 8.7 9.6 9.3 6.6 0.8 4.2 4 1 1 5 5 5 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella Calreticulin PF00262.13 KLO10131.1 - 2.5e-148 493.6 10.8 3.7e-148 493.0 7.5 1.3 1 0 0 1 1 1 1 Calreticulin family GTP_EFTU PF00009.22 KLO10131.1 - 3.9e-43 147.0 0.1 8.4e-43 145.9 0.1 1.6 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.13 KLO10131.1 - 1.3e-25 89.2 0.0 5e-25 87.3 0.0 2.0 2 0 0 2 2 2 1 Elongation factor G, domain IV EFG_C PF00679.19 KLO10131.1 - 6.2e-22 77.2 0.0 2e-21 75.6 0.0 1.9 2 0 0 2 2 2 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 KLO10131.1 - 1.9e-09 37.4 0.1 4.4e-09 36.3 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 Miro PF08477.8 KLO10131.1 - 9.1e-06 26.1 0.2 2.1e-05 24.9 0.1 1.7 1 0 0 1 1 1 1 Miro-like protein EFG_II PF14492.1 KLO10131.1 - 1.9e-05 24.3 0.0 0.00018 21.3 0.0 2.4 2 0 0 2 2 2 1 Elongation Factor G, domain II SRPRB PF09439.5 KLO10131.1 - 0.0071 15.5 0.1 0.015 14.5 0.1 1.5 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Dynamin_N PF00350.18 KLO10131.1 - 0.09 12.5 6.5 0.59 9.9 0.2 3.4 3 1 1 4 4 4 0 Dynamin family Ras PF00071.17 KLO10131.1 - 0.1 11.9 0.1 0.24 10.7 0.1 1.6 1 0 0 1 1 1 0 Ras family RNase_T PF00929.19 KLO10132.1 - 3e-12 47.1 0.0 6.5e-11 42.7 0.0 2.3 1 1 0 1 1 1 1 Exonuclease p450 PF00067.17 KLO10133.1 - 2.4e-55 187.8 0.0 3.1e-55 187.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Zn_clus PF00172.13 KLO10134.1 - 0.00053 19.8 13.2 0.00062 19.6 9.1 1.1 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ada_Zn_binding PF02805.11 KLO10134.1 - 9.5 5.9 11.1 6.9 6.3 1.2 2.4 1 1 1 2 2 2 0 Metal binding domain of Ada Vps5 PF09325.5 KLO10135.1 - 1.9e-18 66.6 0.6 2.7e-18 66.0 0.4 1.1 1 0 0 1 1 1 1 Vps5 C terminal like PX PF00787.19 KLO10135.1 - 6e-10 38.9 0.1 1.6e-09 37.5 0.1 1.7 1 0 0 1 1 1 1 PX domain DUF4200 PF13863.1 KLO10135.1 - 0.13 12.1 2.0 0.38 10.7 1.4 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) TPR_12 PF13424.1 KLO10135.1 - 0.14 12.1 0.6 5.7 6.9 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat Ofd1_CTDD PF10637.4 KLO10137.1 - 1.9e-63 214.0 0.0 2.6e-63 213.6 0.0 1.1 1 0 0 1 1 1 1 Oxoglutarate and iron-dependent oxygenase degradation C-term RRM_6 PF14259.1 KLO10138.1 - 6.2e-20 70.9 0.1 4.7e-10 39.3 0.0 3.5 3 0 0 3 3 3 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 KLO10138.1 - 6.1e-15 54.6 0.0 1.1e-05 24.9 0.0 4.2 3 1 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KLO10138.1 - 3.2e-06 26.9 0.0 0.071 12.9 0.0 2.6 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ycf1 PF05758.7 KLO10138.1 - 7.8 4.0 8.1 14 3.2 5.6 1.5 1 0 0 1 1 1 0 Ycf1 Ribonuclease_3 PF00636.21 KLO10139.1 - 4.1e-38 130.3 3.7 6.3e-18 65.2 0.0 3.4 2 1 0 2 2 2 2 Ribonuclease III domain Ribonucleas_3_3 PF14622.1 KLO10139.1 - 1.1e-23 83.5 0.2 1.7e-09 37.7 0.0 4.4 4 0 0 4 4 4 4 Ribonuclease-III-like Dicer_dimer PF03368.9 KLO10139.1 - 1.7e-11 43.7 0.0 5e-11 42.2 0.0 1.8 1 0 0 1 1 1 1 Dicer dimerisation domain Helicase_C PF00271.26 KLO10139.1 - 2e-05 24.3 0.0 5e-05 23.0 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain PAZ PF02170.17 KLO10139.1 - 0.0062 15.8 0.0 0.014 14.7 0.0 1.5 1 0 0 1 1 1 1 PAZ domain RasGEF_N_2 PF14663.1 KLO10139.1 - 0.028 14.3 0.1 0.15 12.0 0.0 2.1 2 0 0 2 2 2 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain COX7C PF02935.11 KLO10140.1 - 1.5e-15 56.7 0.8 1.9e-15 56.3 0.6 1.3 1 1 0 1 1 1 1 Cytochrome c oxidase subunit VIIc Aldedh PF00171.17 KLO10141.1 - 7.9e-180 598.1 0.1 8.9e-180 597.9 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Zn_clus PF00172.13 KLO10142.1 - 3.2e-06 26.9 13.2 4.9e-06 26.3 9.2 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PAT1 PF09770.4 KLO10142.1 - 0.31 9.2 9.2 0.31 9.2 6.4 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 HypA PF01155.14 KLO10142.1 - 0.37 10.5 4.0 0.56 9.9 2.8 1.2 1 0 0 1 1 1 0 Hydrogenase expression/synthesis hypA family Proteasome PF00227.21 KLO10143.1 - 1.2e-60 204.0 0.0 1.7e-60 203.5 0.0 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 KLO10143.1 - 3.4e-09 35.8 0.2 8.5e-09 34.5 0.0 1.8 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature PAP_central PF04928.12 KLO10144.1 - 1.4e-28 99.4 0.0 3e-28 98.3 0.0 1.5 1 1 0 1 1 1 1 Poly(A) polymerase central domain 2_5_RNA_ligase2 PF13563.1 KLO10144.1 - 1.8e-23 82.9 0.0 3.4e-23 82.0 0.0 1.5 1 0 0 1 1 1 1 2'-5' RNA ligase superfamily Exo_endo_phos PF03372.18 KLO10144.1 - 7.6e-11 42.4 1.2 7.6e-11 42.4 0.8 1.9 2 0 0 2 2 2 1 Endonuclease/Exonuclease/phosphatase family DUF504 PF04457.7 KLO10144.1 - 1.2e-10 41.4 0.3 2.3e-10 40.4 0.2 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF504) LigT_PEase PF02834.11 KLO10144.1 - 3.7e-09 36.4 0.0 0.00059 19.7 0.0 2.6 2 0 0 2 2 2 2 LigT like Phosphoesterase NTP_transf_2 PF01909.18 KLO10144.1 - 0.00011 22.3 0.0 0.00044 20.5 0.0 1.9 1 0 0 1 1 1 1 Nucleotidyltransferase domain PAP_RNA-bind PF04926.10 KLO10144.1 - 0.00023 20.7 0.0 0.00047 19.7 0.0 1.5 1 0 0 1 1 1 1 Poly(A) polymerase predicted RNA binding domain DUF4269 PF14091.1 KLO10144.1 - 0.025 14.5 0.0 0.046 13.6 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4269) AhpC-TSA PF00578.16 KLO10145.1 - 6.8e-31 106.5 0.0 9.7e-31 106.0 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 KLO10145.1 - 8.3e-14 51.3 0.0 1.1e-13 50.9 0.0 1.1 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.4 KLO10145.1 - 1.2e-10 40.8 0.0 2.1e-10 40.0 0.0 1.4 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin PS_Dcarbxylase PF02666.10 KLO10145.1 - 0.16 11.2 0.0 0.25 10.6 0.0 1.2 1 0 0 1 1 1 0 Phosphatidylserine decarboxylase Ssu72 PF04722.8 KLO10146.1 - 4.2e-80 267.7 0.0 5.8e-80 267.2 0.0 1.2 1 0 0 1 1 1 1 Ssu72-like protein PAT1 PF09770.4 KLO10146.1 - 4.8 5.3 17.7 6.2 4.9 12.2 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 F-box-like PF12937.2 KLO10147.1 - 0.00029 20.5 0.8 0.0026 17.4 0.1 2.6 2 0 0 2 2 2 1 F-box-like Laminin_II PF06009.7 KLO10147.1 - 0.063 13.0 0.5 0.14 11.9 0.4 1.5 1 0 0 1 1 1 0 Laminin Domain II LRR_6 PF13516.1 KLO10147.1 - 0.1 12.7 0.3 1.4e+02 3.0 0.0 4.5 4 0 0 4 4 4 0 Leucine Rich repeat LRR_4 PF12799.2 KLO10147.1 - 0.15 11.7 3.7 35 4.1 0.0 5.0 4 2 1 6 6 6 0 Leucine Rich repeats (2 copies) Lge1 PF11488.3 KLO10147.1 - 0.17 12.0 0.9 1.1 9.4 0.2 2.3 2 0 0 2 2 2 0 Transcriptional regulatory protein LGE1 Nop PF01798.13 KLO10148.1 - 1.6e-43 147.5 0.4 1.6e-43 147.5 0.2 1.6 2 0 0 2 2 2 1 Putative snoRNA binding domain Prp31_C PF09785.4 KLO10148.1 - 4.9e-41 140.0 3.9 8.5e-41 139.2 2.7 1.4 1 0 0 1 1 1 1 Prp31 C terminal domain NOSIC PF08060.8 KLO10148.1 - 5.8e-18 64.4 0.1 1.7e-17 62.9 0.1 1.9 1 0 0 1 1 1 1 NOSIC (NUC001) domain NifU_N PF01592.11 KLO10149.1 - 6.5e-50 168.3 0.0 9.7e-50 167.7 0.0 1.3 1 0 0 1 1 1 1 NifU-like N terminal domain AAA_10 PF12846.2 KLO10150.1 - 5.9e-11 42.3 0.0 7.5e-10 38.7 0.0 2.2 1 1 0 1 1 1 1 AAA-like domain Zot PF05707.7 KLO10150.1 - 2e-08 33.9 0.0 2.6e-07 30.3 0.0 2.1 2 0 0 2 2 2 1 Zonular occludens toxin (Zot) AAA_22 PF13401.1 KLO10150.1 - 6.6e-05 23.0 0.0 0.36 10.9 0.0 2.6 2 1 0 2 2 2 2 AAA domain FtsK_SpoIIIE PF01580.13 KLO10150.1 - 0.0013 18.2 0.0 0.036 13.5 0.0 2.2 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA PF00004.24 KLO10150.1 - 0.0021 18.2 0.0 0.052 13.7 0.0 2.2 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) SpoIIAA-like PF11964.3 KLO10150.1 - 0.0061 16.8 0.0 0.013 15.7 0.0 1.6 1 0 0 1 1 1 1 SpoIIAA-like Zeta_toxin PF06414.7 KLO10150.1 - 0.0095 15.0 0.0 0.018 14.1 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin AAA_33 PF13671.1 KLO10150.1 - 0.021 14.7 0.0 0.29 10.9 0.0 2.4 2 0 0 2 2 2 0 AAA domain DUF87 PF01935.12 KLO10150.1 - 0.035 13.9 0.1 0.64 9.8 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function DUF87 Sugarporin_N PF11471.3 KLO10150.1 - 0.048 13.3 0.3 0.048 13.3 0.2 2.6 3 0 0 3 3 3 0 Maltoporin periplasmic N-terminal extension DUF853 PF05872.7 KLO10150.1 - 0.084 11.2 0.0 0.084 11.2 0.0 1.6 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF853) AAA_14 PF13173.1 KLO10150.1 - 0.11 12.4 0.0 19 5.1 0.0 2.5 2 0 0 2 2 2 0 AAA domain Retinal PF15449.1 KLO10150.1 - 0.47 8.0 8.9 0.6 7.7 6.2 1.1 1 0 0 1 1 1 0 Retinal protein CDC27 PF09507.5 KLO10150.1 - 1.6 7.8 10.8 2.2 7.4 7.5 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Methyltransf_8 PF05148.10 KLO10151.1 - 1.7e-66 224.0 0.0 2.8e-66 223.2 0.0 1.4 1 0 0 1 1 1 1 Hypothetical methyltransferase Methyltransf_23 PF13489.1 KLO10151.1 - 7.9e-08 32.1 0.0 1.2e-07 31.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KLO10151.1 - 1.7e-06 28.3 0.0 5.1e-06 26.8 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KLO10151.1 - 0.00039 20.0 0.1 0.0023 17.5 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KLO10151.1 - 0.0013 19.1 0.1 0.013 15.9 0.0 2.7 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 KLO10151.1 - 0.024 14.9 0.1 0.22 11.9 0.0 2.5 2 1 0 2 2 2 0 Methyltransferase domain MetW PF07021.7 KLO10151.1 - 0.078 12.3 0.0 0.13 11.6 0.0 1.3 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW UPRTase PF14681.1 KLO10152.1 - 4.1e-66 222.1 0.0 4.7e-66 221.9 0.0 1.0 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.22 KLO10152.1 - 0.003 17.2 0.0 0.0051 16.5 0.0 1.4 1 0 0 1 1 1 1 Phosphoribosyl transferase domain FAD_binding_1 PF00667.15 KLO10153.1 - 7.3e-52 175.9 0.0 1.1e-51 175.3 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain NAD_binding_1 PF00175.16 KLO10153.1 - 4.8e-09 36.7 0.0 1.2e-08 35.5 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.19 KLO10153.1 - 0.034 14.2 0.0 0.092 12.8 0.0 1.7 1 0 0 1 1 1 0 Oxidoreductase FAD-binding domain Glyco_hydro_9 PF00759.14 KLO10154.1 - 1.7e-88 297.5 6.2 2.2e-88 297.1 4.3 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 9 SKG6 PF08693.5 KLO10154.1 - 0.00045 19.4 1.2 0.00089 18.5 0.8 1.5 1 0 0 1 1 1 1 Transmembrane alpha-helix domain DUF4448 PF14610.1 KLO10154.1 - 0.1 12.0 0.0 0.17 11.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) F-box-like PF12937.2 KLO10155.1 - 0.00012 21.7 0.0 0.0004 20.0 0.0 2.0 1 1 0 1 1 1 1 F-box-like GFO_IDH_MocA PF01408.17 KLO10156.1 - 6.3e-20 71.8 0.0 1.1e-19 71.1 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 KLO10156.1 - 1.2e-08 34.7 0.0 2.4e-08 33.7 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain Semialdhyde_dh PF01118.19 KLO10156.1 - 0.013 15.8 0.0 0.025 14.9 0.0 1.5 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain NAD_binding_3 PF03447.11 KLO10156.1 - 0.06 13.7 0.0 0.12 12.8 0.0 1.4 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain WD40 PF00400.27 KLO10157.1 - 4e-18 64.5 6.7 3.5e-07 29.8 0.5 6.3 6 0 0 6 6 6 5 WD domain, G-beta repeat eIF2A PF08662.6 KLO10157.1 - 3.8e-05 23.4 0.1 0.023 14.3 0.0 2.8 3 0 0 3 3 3 2 Eukaryotic translation initiation factor eIF2A Gmad1 PF10647.4 KLO10157.1 - 0.0006 19.2 0.6 0.12 11.7 0.1 2.2 2 0 0 2 2 2 2 Lipoprotein LpqB beta-propeller domain Cytochrom_D1 PF02239.11 KLO10157.1 - 0.0062 14.8 0.0 0.071 11.4 0.0 2.2 2 0 0 2 2 2 1 Cytochrome D1 heme domain DUF2454 PF10521.4 KLO10158.1 - 1.1e-33 116.5 0.0 1.3e-33 116.2 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2454) WD40 PF00400.27 KLO10159.1 - 4.8e-13 48.4 4.3 1.8e-05 24.3 0.0 4.3 4 0 0 4 4 4 3 WD domain, G-beta repeat GFO_IDH_MocA PF01408.17 KLO10161.1 - 4.6e-19 69.1 0.0 8.2e-19 68.2 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 KLO10161.1 - 9.8e-09 35.0 0.0 1.7e-08 34.2 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain NAD_binding_3 PF03447.11 KLO10161.1 - 0.0022 18.3 0.0 0.0041 17.4 0.0 1.4 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain Semialdhyde_dh PF01118.19 KLO10161.1 - 0.033 14.5 0.0 0.059 13.6 0.0 1.4 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain GFO_IDH_MocA PF01408.17 KLO10162.1 - 9.3e-19 68.1 0.0 1.7e-18 67.2 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 KLO10162.1 - 5.8e-10 38.9 0.0 1.2e-09 37.9 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain NAD_binding_3 PF03447.11 KLO10162.1 - 0.011 16.1 0.0 0.04 14.3 0.0 1.9 2 0 0 2 2 2 0 Homoserine dehydrogenase, NAD binding domain Semialdhyde_dh PF01118.19 KLO10162.1 - 0.082 13.2 0.0 0.15 12.3 0.0 1.4 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain ubiquitin PF00240.18 KLO10163.1 - 2e-08 33.5 0.0 4.3e-08 32.4 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family DUF2407 PF10302.4 KLO10163.1 - 0.0054 16.8 0.0 0.017 15.2 0.0 1.9 2 0 0 2 2 2 1 DUF2407 ubiquitin-like domain DUF4633 PF15464.1 KLO10163.1 - 0.36 10.6 3.5 0.96 9.3 2.4 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4633) MARVEL PF01284.18 KLO10164.1 - 9.5e-11 41.7 8.9 9.5e-11 41.7 6.2 1.9 1 1 1 2 2 2 1 Membrane-associating domain DUF1183 PF06682.7 KLO10164.1 - 0.044 13.4 0.1 0.044 13.4 0.1 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1183) PDR_CDR PF06422.7 KLO10164.1 - 0.21 11.2 0.1 0.21 11.2 0.1 1.9 2 0 0 2 2 2 0 CDR ABC transporter Chromate_transp PF02417.10 KLO10165.1 - 0.074 12.6 0.1 0.095 12.2 0.1 1.2 1 1 0 1 1 1 0 Chromate transporter MBOAT PF03062.14 KLO10167.1 - 8.9e-39 133.4 0.9 8.9e-39 133.4 0.6 2.0 2 0 0 2 2 2 1 MBOAT, membrane-bound O-acyltransferase family DUF1925 PF09094.6 KLO10167.1 - 0.079 12.9 0.2 0.21 11.5 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1925) F-box-like PF12937.2 KLO10168.1 - 1.8e-05 24.3 0.8 0.00026 20.6 0.9 2.8 2 1 0 2 2 2 1 F-box-like Brix PF04427.13 KLO10169.1 - 6.5e-48 162.9 1.7 8.9e-48 162.4 1.2 1.2 1 0 0 1 1 1 1 Brix domain DUF2517 PF10725.4 KLO10169.1 - 0.098 12.3 0.0 0.25 11.0 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2517) p450 PF00067.17 KLO10170.1 - 3.2e-78 263.3 0.0 4.6e-78 262.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 FAD_binding_1 PF00667.15 KLO10170.1 - 4.6e-28 98.1 0.0 8.4e-28 97.3 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.20 KLO10170.1 - 4.2e-21 75.4 0.0 8.8e-21 74.3 0.0 1.6 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.16 KLO10170.1 - 3.5e-11 43.6 0.0 8.3e-11 42.4 0.0 1.7 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain RRM_1 PF00076.17 KLO10172.1 - 5e-16 58.0 0.0 6.7e-16 57.6 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KLO10172.1 - 4.7e-12 45.5 0.0 6.2e-12 45.1 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KLO10172.1 - 5.9e-12 45.3 0.0 9e-12 44.8 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Ribosomal_L18e PF00828.14 KLO10173.1 - 6.2e-23 81.5 0.0 6.2e-23 81.5 0.0 1.6 2 0 0 2 2 2 1 Ribosomal protein L18e/L15 Histone PF00125.19 KLO10175.1 - 8.8e-29 99.4 0.2 1.4e-28 98.8 0.1 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 KLO10175.1 - 0.0094 16.1 0.1 0.015 15.4 0.1 1.4 1 0 0 1 1 1 1 Kinetochore component CENP-S CBFD_NFYB_HMF PF00808.18 KLO10175.1 - 0.0097 15.9 0.5 0.09 12.8 0.1 2.2 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-T PF15511.1 KLO10175.1 - 0.12 11.6 5.6 0.5 9.5 3.9 1.9 1 1 0 1 1 1 0 Centromere kinetochore component CENP-T Pinin_SDK_N PF04697.8 KLO10176.1 - 0.13 12.3 0.3 0.24 11.4 0.2 1.4 1 0 0 1 1 1 0 pinin/SDK conserved region TRAM_LAG1_CLN8 PF03798.11 KLO10177.1 - 2.5e-30 105.5 24.6 2.5e-30 105.5 17.0 1.7 2 0 0 2 2 2 1 TLC domain TRAM1 PF08390.6 KLO10177.1 - 4.2e-15 55.0 0.1 1e-14 53.7 0.1 1.7 1 0 0 1 1 1 1 TRAM1-like protein F-box-like PF12937.2 KLO10178.1 - 3.9e-07 29.6 0.7 9.8e-07 28.4 0.1 2.1 2 0 0 2 2 2 1 F-box-like DUF3719 PF12516.3 KLO10178.1 - 0.025 14.1 0.3 0.14 11.7 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3719) F-box PF00646.28 KLO10178.1 - 0.031 13.9 0.5 0.031 13.9 0.4 3.3 3 1 0 3 3 3 0 F-box domain F-box-like PF12937.2 KLO10179.1 - 1.2e-07 31.3 4.1 4.1e-07 29.6 0.0 3.3 4 0 0 4 4 4 1 F-box-like F-box PF00646.28 KLO10179.1 - 0.02 14.5 0.2 0.02 14.5 0.1 2.6 2 0 0 2 2 2 0 F-box domain BORG_CEP PF14957.1 KLO10179.1 - 0.048 14.5 0.8 2.6 8.9 0.2 2.5 2 0 0 2 2 2 0 Cdc42 effector F-box-like PF12937.2 KLO10180.1 - 1.6e-07 30.8 0.2 1.6e-07 30.8 0.1 2.1 3 0 0 3 3 3 1 F-box-like F-box-like PF12937.2 KLO10181.1 - 2.6e-05 23.8 0.3 0.00016 21.3 0.0 2.3 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 KLO10181.1 - 0.015 14.9 1.9 0.19 11.4 0.2 3.4 2 1 0 2 2 2 0 F-box domain Glyco_hydro_10 PF00331.15 KLO10182.1 - 7.7e-91 304.4 0.0 8.9e-91 304.2 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 CBFD_NFYB_HMF PF00808.18 KLO10184.1 - 2.8e-16 59.2 0.3 2.8e-16 59.2 0.2 1.5 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 KLO10184.1 - 2.9e-07 30.5 0.1 4.3e-07 29.9 0.0 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TAFII28 PF04719.9 KLO10184.1 - 0.00069 19.3 0.2 0.001 18.8 0.1 1.2 1 0 0 1 1 1 1 hTAFII28-like protein conserved region Ribosomal_60s PF00428.14 KLO10184.1 - 6 7.3 8.5 19 5.7 5.9 2.0 1 1 0 1 1 1 0 60s Acidic ribosomal protein Cyt-b5 PF00173.23 KLO10185.1 - 9.7e-11 41.3 0.0 1.2e-10 40.9 0.0 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Sld5 PF05916.6 KLO10188.1 - 0.00014 22.1 0.3 0.00026 21.2 0.2 1.4 1 0 0 1 1 1 1 GINS complex protein Histone PF00125.19 KLO10190.1 - 3.8e-14 52.5 0.1 4.5e-14 52.3 0.1 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TAF PF02969.12 KLO10190.1 - 4.1e-05 23.4 0.1 5.8e-05 22.9 0.1 1.4 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CENP-S PF15630.1 KLO10190.1 - 4.4e-05 23.5 0.0 5.7e-05 23.2 0.0 1.3 1 1 0 1 1 1 1 Kinetochore component CENP-S CBFD_NFYB_HMF PF00808.18 KLO10190.1 - 0.00061 19.8 0.2 0.0012 18.8 0.1 1.6 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-T PF15511.1 KLO10190.1 - 0.044 13.0 0.0 0.044 13.0 0.0 1.1 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T TFIID-31kDa PF02291.10 KLO10190.1 - 0.069 12.9 0.0 0.089 12.5 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.8 KLO10190.1 - 0.078 12.7 0.0 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 Bromodomain associated Hydrophobin PF01185.13 KLO10192.1 - 1.8e-11 44.2 7.3 2.4e-11 43.9 5.1 1.2 1 0 0 1 1 1 1 Fungal hydrophobin P12 PF12669.2 KLO10192.1 - 0.59 10.3 0.1 0.59 10.3 0.1 2.1 2 0 0 2 2 2 0 Virus attachment protein p12 family Toxin_12 PF07740.7 KLO10192.1 - 5.6 7.5 10.4 6.8 7.2 0.4 2.5 3 0 0 3 3 3 0 Ion channel inhibitory toxin Methyltransf_23 PF13489.1 KLO10193.1 - 1.9e-11 43.9 0.0 2.7e-11 43.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KLO10193.1 - 1.3e-06 28.7 0.0 5.3e-06 26.8 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KLO10193.1 - 4.2e-05 23.9 0.0 0.00015 22.1 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KLO10193.1 - 9.6e-05 22.0 0.0 0.36 10.4 0.0 2.2 2 0 0 2 2 2 2 Methyltransferase domain RrnaAD PF00398.15 KLO10193.1 - 0.0035 16.3 0.0 0.0058 15.6 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_18 PF12847.2 KLO10193.1 - 0.0043 17.6 0.0 0.0082 16.7 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KLO10193.1 - 0.021 14.2 0.0 0.039 13.3 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_26 PF13659.1 KLO10193.1 - 0.025 14.5 0.2 0.089 12.8 0.1 1.9 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_23 PF13489.1 KLO10194.1 - 1.5e-13 50.8 0.0 2.2e-13 50.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KLO10194.1 - 3.6e-05 24.1 0.0 0.076 13.5 0.0 2.3 1 1 1 2 2 2 2 Methyltransferase domain Methyltransf_12 PF08242.7 KLO10194.1 - 8.1e-05 23.0 0.0 0.00031 21.1 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KLO10194.1 - 0.00065 20.2 0.0 0.0015 19.0 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain RrnaAD PF00398.15 KLO10194.1 - 0.0033 16.4 0.0 0.0051 15.8 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_31 PF13847.1 KLO10194.1 - 0.0044 16.6 0.0 1.6 8.3 0.0 2.2 2 0 0 2 2 2 2 Methyltransferase domain DUF2537 PF10801.3 KLO10194.1 - 0.056 13.5 0.6 0.13 12.4 0.4 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2537) Methyltransf_32 PF13679.1 KLO10194.1 - 0.15 11.7 0.0 0.25 11.0 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Pkinase PF00069.20 KLO10195.1 - 1e-41 142.8 0.0 1.8e-41 142.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KLO10195.1 - 1e-33 116.5 0.0 1.7e-33 115.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase SH3_1 PF00018.23 KLO10195.1 - 1.8e-12 46.4 3.1 2.3e-08 33.2 0.1 3.2 2 1 0 2 2 2 2 SH3 domain SH3_9 PF14604.1 KLO10195.1 - 5.9e-12 44.9 0.5 4.8e-08 32.4 0.2 3.1 3 1 0 3 3 3 2 Variant SH3 domain SH3_2 PF07653.12 KLO10195.1 - 3.2e-10 39.3 0.1 1.5e-07 30.7 0.0 2.5 2 0 0 2 2 2 2 Variant SH3 domain Kinase-like PF14531.1 KLO10195.1 - 0.0015 17.5 0.0 0.0027 16.7 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 KLO10195.1 - 0.0025 17.6 0.0 0.054 13.2 0.0 2.5 2 1 0 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.17 KLO10195.1 - 0.0034 16.7 0.4 0.011 15.1 0.0 1.9 2 0 0 2 2 2 1 RIO1 family RA PF00788.18 KLO10195.1 - 0.0053 17.2 0.0 0.012 16.0 0.0 1.6 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain F-box-like PF12937.2 KLO10196.1 - 0.00023 20.8 0.4 0.00023 20.8 0.3 2.1 2 0 0 2 2 2 1 F-box-like F-box-like_2 PF13013.1 KLO10196.1 - 0.0094 15.6 0.0 0.019 14.7 0.0 1.6 1 0 0 1 1 1 1 F-box-like domain F-box PF00646.28 KLO10196.1 - 0.017 14.7 0.5 0.077 12.6 0.3 2.2 1 0 0 1 1 1 0 F-box domain Hydrophobin PF01185.13 KLO10198.1 - 4.8e-22 78.2 11.7 6.8e-22 77.7 8.1 1.2 1 0 0 1 1 1 1 Fungal hydrophobin WWbp PF10349.4 KLO10198.1 - 4 8.3 8.3 6.8 7.6 5.8 1.4 1 0 0 1 1 1 0 WW-domain ligand protein F-box-like PF12937.2 KLO10200.1 - 3.9e-07 29.6 1.2 8.9e-06 25.3 0.0 2.6 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 KLO10200.1 - 0.012 15.2 0.1 0.012 15.2 0.1 3.9 4 1 0 4 4 4 0 F-box domain F-box-like PF12937.2 KLO10201.1 - 3.8e-06 26.5 0.0 3.8e-06 26.5 0.0 3.5 4 1 0 4 4 4 1 F-box-like F-box PF00646.28 KLO10201.1 - 0.22 11.2 5.7 0.4 10.4 0.2 3.6 3 1 0 3 3 3 0 F-box domain F-box-like PF12937.2 KLO10202.1 - 0.054 13.2 0.2 0.95 9.2 0.0 2.5 2 0 0 2 2 2 0 F-box-like F-box-like PF12937.2 KLO10203.1 - 7.9e-06 25.5 0.7 2.7e-05 23.7 0.0 2.3 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 KLO10203.1 - 0.21 11.2 5.0 1.9 8.2 0.1 3.7 3 0 0 3 3 3 0 F-box domain F-box-like PF12937.2 KLO10204.1 - 1.2e-06 28.1 0.1 1.2e-05 24.9 0.1 2.3 2 0 0 2 2 2 1 F-box-like DUF4234 PF14018.1 KLO10204.1 - 0.024 14.3 0.0 0.062 13.0 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4234) RE_SinI PF09570.5 KLO10204.1 - 0.081 11.8 0.0 0.17 10.8 0.0 1.5 1 0 0 1 1 1 0 SinI restriction endonuclease F-box PF00646.28 KLO10204.1 - 1.6 8.4 4.5 1.1 8.9 0.6 2.7 2 1 0 2 2 2 0 F-box domain ABC_tran PF00005.22 KLO10205.1 - 3e-35 121.4 0.0 3.7e-17 62.9 0.0 2.6 2 1 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 KLO10205.1 - 4.9e-15 56.2 1.7 0.0058 16.6 0.0 4.5 2 2 2 4 4 4 4 AAA domain SMC_N PF02463.14 KLO10205.1 - 1.3e-10 40.9 2.3 0.0012 18.0 0.1 3.6 2 2 1 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_15 PF13175.1 KLO10205.1 - 1.3e-07 31.0 0.7 0.58 9.1 0.0 4.1 3 1 1 4 4 4 2 AAA ATPase domain DUF258 PF03193.11 KLO10205.1 - 3.3e-06 26.3 0.0 0.0061 15.7 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_22 PF13401.1 KLO10205.1 - 1.1e-05 25.5 0.0 0.0029 17.7 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 KLO10205.1 - 7.3e-05 22.8 0.3 0.007 16.3 0.0 2.5 2 1 0 2 2 2 1 AAA ATPase domain NACHT PF05729.7 KLO10205.1 - 0.00045 19.9 0.2 0.1 12.2 0.0 2.5 2 0 0 2 2 2 1 NACHT domain SbcCD_C PF13558.1 KLO10205.1 - 0.0014 18.5 0.2 2.5 8.0 0.0 3.7 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_18 PF13238.1 KLO10205.1 - 0.0017 18.6 0.0 0.17 12.2 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 KLO10205.1 - 0.0019 19.0 0.3 0.13 13.1 0.0 2.7 2 2 0 2 2 2 1 AAA domain Miro PF08477.8 KLO10205.1 - 0.0019 18.6 0.1 0.21 12.1 0.0 2.8 3 0 0 3 3 2 1 Miro-like protein AAA_29 PF13555.1 KLO10205.1 - 0.0038 16.7 2.1 1.9 8.0 0.1 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA PF00004.24 KLO10205.1 - 0.0046 17.1 0.0 2.6 8.2 0.0 2.6 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) NB-ARC PF00931.17 KLO10205.1 - 0.0088 14.9 0.1 1 8.1 0.0 2.3 2 0 0 2 2 2 1 NB-ARC domain AAA_23 PF13476.1 KLO10205.1 - 0.01 16.1 2.6 0.61 10.3 0.1 2.7 3 0 0 3 3 2 0 AAA domain AAA_5 PF07728.9 KLO10205.1 - 0.01 15.5 0.1 2.3 7.9 0.0 3.1 4 0 0 4 4 2 0 AAA domain (dynein-related subfamily) Rad17 PF03215.10 KLO10205.1 - 0.013 14.2 0.0 0.095 11.3 0.0 2.0 2 0 0 2 2 2 0 Rad17 cell cycle checkpoint protein SRP54 PF00448.17 KLO10205.1 - 0.015 14.7 1.1 1.4 8.3 0.0 2.3 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain VirE PF05272.6 KLO10205.1 - 0.018 14.5 0.0 1.7 8.0 0.0 2.5 2 0 0 2 2 2 0 Virulence-associated protein E AAA_14 PF13173.1 KLO10205.1 - 0.019 14.8 0.0 9.9 6.0 0.0 3.0 3 0 0 3 3 2 0 AAA domain AAA_33 PF13671.1 KLO10205.1 - 0.027 14.3 0.0 2.1 8.2 0.0 2.7 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.18 KLO10205.1 - 0.027 14.4 0.0 1.7 8.5 0.0 2.6 2 1 0 2 2 2 0 50S ribosome-binding GTPase MobB PF03205.9 KLO10205.1 - 0.031 13.9 1.1 3.7 7.2 0.1 2.5 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_28 PF13521.1 KLO10205.1 - 0.037 13.9 0.0 5.5 6.9 0.0 2.4 2 0 0 2 2 2 0 AAA domain PduV-EutP PF10662.4 KLO10205.1 - 0.04 13.4 1.0 0.43 10.0 0.0 2.8 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation RNA_helicase PF00910.17 KLO10205.1 - 0.045 13.9 0.0 15 5.8 0.0 2.4 2 0 0 2 2 2 0 RNA helicase AAA_24 PF13479.1 KLO10205.1 - 0.055 13.0 0.2 1 8.8 0.0 2.3 2 0 0 2 2 2 0 AAA domain Arch_ATPase PF01637.13 KLO10205.1 - 0.071 12.7 0.0 3.4 7.3 0.0 2.2 2 0 0 2 2 2 0 Archaeal ATPase UPF0079 PF02367.12 KLO10205.1 - 0.087 12.4 0.1 1.1 8.8 0.0 2.3 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 F-box-like PF12937.2 KLO10206.1 - 3.5e-06 26.6 0.1 2.3e-05 24.0 0.0 2.4 2 0 0 2 2 2 1 F-box-like FTO_CTD PF12934.2 KLO10206.1 - 0.07 12.6 0.1 0.16 11.5 0.0 1.5 1 0 0 1 1 1 0 FTO C-terminal domain F-box PF00646.28 KLO10206.1 - 0.23 11.1 3.9 0.75 9.5 0.4 3.5 3 1 0 3 3 3 0 F-box domain F-box-like PF12937.2 KLO10207.1 - 3.6e-08 33.0 1.2 9.3e-07 28.4 0.0 2.5 2 0 0 2 2 2 1 F-box-like BLOC1_2 PF10046.4 KLO10207.1 - 0.024 14.7 0.8 1.2 9.2 0.1 2.4 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 RRM_1 PF00076.17 KLO10208.1 - 0.00042 19.8 0.0 0.0023 17.5 0.0 2.2 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) F-box-like PF12937.2 KLO10208.1 - 0.0005 19.7 0.0 0.0005 19.7 0.0 2.3 3 0 0 3 3 3 1 F-box-like F-box PF00646.28 KLO10208.1 - 0.042 13.5 3.8 0.094 12.4 0.1 3.1 2 1 0 2 2 2 0 F-box domain RE_SinI PF09570.5 KLO10208.1 - 0.1 11.5 0.0 0.16 10.8 0.0 1.3 1 0 0 1 1 1 0 SinI restriction endonuclease DUF1912 PF08930.5 KLO10208.1 - 0.13 12.3 0.0 0.33 11.0 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1912) F-box-like PF12937.2 KLO10209.1 - 1.4e-05 24.7 0.0 0.00077 19.1 0.0 3.1 3 0 0 3 3 3 1 F-box-like Tektin PF03148.9 KLO10209.1 - 0.11 10.9 1.0 0.17 10.4 0.7 1.1 1 0 0 1 1 1 0 Tektin family F-box-like PF12937.2 KLO10210.1 - 0.004 16.8 0.3 0.004 16.8 0.2 3.0 3 0 0 3 3 3 1 F-box-like DUF1736 PF08409.6 KLO10210.1 - 0.036 13.6 0.1 0.092 12.3 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1736) Helicase_C PF00271.26 KLO10216.1 - 2.7e-13 49.5 0.0 6.1e-13 48.4 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 KLO10216.1 - 8.3e-08 31.9 0.0 1.8e-06 27.5 0.0 2.3 2 0 0 2 2 2 1 DEAD/DEAH box helicase DEAD PF00270.24 KLO10217.1 - 1.4e-11 44.2 0.0 1.5e-11 44.0 0.0 1.0 1 0 0 1 1 1 1 DEAD/DEAH box helicase SecA_DEAD PF07517.9 KLO10217.1 - 0.00026 20.3 0.0 0.00029 20.2 0.0 1.1 1 0 0 1 1 1 1 SecA DEAD-like domain ResIII PF04851.10 KLO10217.1 - 0.053 13.3 0.0 0.053 13.3 0.0 1.1 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_19 PF13245.1 KLO10217.1 - 0.11 12.2 0.0 0.16 11.7 0.0 1.2 1 0 0 1 1 1 0 Part of AAA domain Na_Ca_ex PF01699.19 KLO10218.1 - 1.6e-10 40.7 20.5 1.3e-06 28.0 3.1 3.3 2 2 1 3 3 3 2 Sodium/calcium exchanger protein DUF2968 PF11180.3 KLO10220.1 - 0.12 11.7 0.5 0.13 11.6 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) DUF2746 PF10874.3 KLO10220.1 - 0.13 12.4 8.6 1.7 8.8 5.9 2.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2746) tRNA-synt_1b PF00579.20 KLO10221.1 - 7.6e-57 192.6 0.0 3.1e-56 190.6 0.0 1.8 1 1 0 1 1 1 1 tRNA synthetases class I (W and Y) NACHT PF05729.7 KLO10224.1 - 5.5e-09 35.9 0.0 1.3e-08 34.7 0.0 1.7 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 KLO10224.1 - 0.0012 18.8 0.0 0.027 14.4 0.0 2.5 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 KLO10224.1 - 0.068 13.3 0.0 0.88 9.7 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA PF00004.24 KLO10225.1 - 9.1e-17 61.4 0.0 5.7e-16 58.9 0.0 2.2 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.1 KLO10225.1 - 0.006 16.8 0.0 0.024 14.9 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.9 KLO10225.1 - 0.012 15.2 0.0 0.026 14.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 KLO10225.1 - 0.014 15.4 1.3 0.18 11.9 0.3 2.4 1 1 1 2 2 2 0 AAA domain AAA_16 PF13191.1 KLO10225.1 - 0.037 14.0 0.0 0.091 12.7 0.0 1.8 1 0 0 1 1 1 0 AAA ATPase domain Zeta_toxin PF06414.7 KLO10225.1 - 0.07 12.2 0.0 0.2 10.7 0.0 1.7 1 0 0 1 1 1 0 Zeta toxin Zot PF05707.7 KLO10225.1 - 0.072 12.5 0.5 1.1 8.6 0.3 2.3 1 1 0 1 1 1 0 Zonular occludens toxin (Zot) AAA_19 PF13245.1 KLO10225.1 - 0.097 12.4 0.1 0.23 11.2 0.1 1.6 1 0 0 1 1 1 0 Part of AAA domain AAA_17 PF13207.1 KLO10225.1 - 0.21 12.3 1.7 0.64 10.8 0.0 2.5 2 2 0 2 2 2 0 AAA domain F-box-like PF12937.2 KLO10227.1 - 6.7e-06 25.7 0.4 4e-05 23.2 0.3 2.5 1 1 0 1 1 1 1 F-box-like LRR_4 PF12799.2 KLO10227.1 - 0.17 11.5 3.6 2.5 7.8 0.1 3.3 4 0 0 4 4 4 0 Leucine Rich repeats (2 copies) eIF-3_zeta PF05091.7 KLO10228.1 - 7e-169 562.7 0.0 9.5e-169 562.3 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) CUE PF02845.11 KLO10229.1 - 3.4e-05 23.2 0.0 5.7e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 CUE domain Rhomboid PF01694.17 KLO10229.1 - 5.2e-05 23.3 7.5 8.4e-05 22.6 5.2 1.3 1 0 0 1 1 1 1 Rhomboid family DUF3752 PF12572.3 KLO10229.1 - 0.21 11.7 7.3 0.29 11.2 5.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3752) ApbA PF02558.11 KLO10230.1 - 5.5e-22 77.8 0.0 8.5e-22 77.2 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA ApbA_C PF08546.6 KLO10230.1 - 4.8e-21 75.0 0.2 1.9e-20 73.1 0.0 1.9 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA C terminal DUF3049 PF11250.3 KLO10233.1 - 0.078 12.7 0.0 0.23 11.2 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3049) DUF4630 PF15443.1 KLO10233.1 - 0.15 11.8 0.1 0.22 11.3 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4630) GATA PF00320.22 KLO10235.1 - 9.3e-09 34.4 4.6 1.7e-08 33.6 3.2 1.5 1 0 0 1 1 1 1 GATA zinc finger PHD PF00628.24 KLO10236.1 - 5.8e-09 35.5 6.1 8.9e-09 34.9 4.2 1.3 1 0 0 1 1 1 1 PHD-finger ING PF12998.2 KLO10236.1 - 4.3e-07 30.1 1.0 2.9e-06 27.5 0.7 2.0 1 1 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding zf-HC5HC2H PF13771.1 KLO10236.1 - 0.018 15.1 0.1 0.039 14.0 0.1 1.5 1 0 0 1 1 1 0 PHD-like zinc-binding domain TRP PF06011.7 KLO10237.1 - 8.2e-53 179.5 15.6 2.6e-52 177.8 10.9 1.8 1 1 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.1 KLO10237.1 - 8.2e-06 25.8 0.1 1.5e-05 25.0 0.0 1.4 1 0 0 1 1 1 1 ML-like domain CNH PF00780.17 KLO10238.1 - 3.2e-06 26.7 0.0 0.0088 15.4 0.0 2.3 2 0 0 2 2 2 2 CNH domain Kelch_4 PF13418.1 KLO10239.1 - 4.1e-18 64.8 18.6 0.0064 16.2 0.1 7.4 7 0 0 7 7 7 6 Galactose oxidase, central domain Kelch_3 PF13415.1 KLO10239.1 - 2.1e-15 56.4 22.0 0.012 15.7 0.1 6.9 7 0 0 7 7 7 5 Galactose oxidase, central domain Kelch_5 PF13854.1 KLO10239.1 - 1.1e-08 34.8 4.7 0.84 9.6 0.1 5.0 4 0 0 4 4 4 4 Kelch motif Kelch_6 PF13964.1 KLO10239.1 - 1.3e-06 28.2 10.9 0.18 12.0 0.1 6.4 6 0 0 6 6 6 2 Kelch motif Kelch_1 PF01344.20 KLO10239.1 - 0.00031 20.2 6.9 7 6.2 0.1 5.4 6 0 0 6 6 6 3 Kelch motif RNase_H2-Ydr279 PF09468.5 KLO10240.1 - 1.7 7.7 9.8 3.5 6.7 6.8 1.5 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) Peptidase_S49_N PF08496.5 KLO10240.1 - 2.2 8.0 5.8 4.6 7.0 4.0 1.4 1 0 0 1 1 1 0 Peptidase family S49 N-terminal HSP90 PF00183.13 KLO10241.1 - 1.9e-128 429.1 11.8 2.5e-128 428.8 8.2 1.1 1 0 0 1 1 1 1 Hsp90 protein HATPase_c_3 PF13589.1 KLO10241.1 - 2.8e-07 30.2 0.0 6.8e-07 29.0 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 KLO10241.1 - 2.1e-05 24.2 0.0 6.1e-05 22.7 0.0 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Phi-29_GP4 PF05464.6 KLO10241.1 - 0.05 13.4 0.0 0.13 12.1 0.0 1.7 1 0 0 1 1 1 0 Phi-29-like late genes activator (early protein GP4) AAA PF00004.24 KLO10242.1 - 3.5e-16 59.6 0.0 8.1e-16 58.4 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 KLO10242.1 - 0.0076 15.9 0.0 0.016 14.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 KLO10242.1 - 0.014 15.5 0.9 0.065 13.3 0.1 2.1 1 1 1 2 2 2 0 AAA domain AAA_18 PF13238.1 KLO10242.1 - 0.042 14.1 0.0 0.12 12.6 0.0 1.9 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.7 KLO10242.1 - 0.045 12.8 0.2 0.11 11.5 0.1 1.6 1 0 0 1 1 1 0 Zeta toxin AAA_16 PF13191.1 KLO10242.1 - 0.059 13.3 0.0 0.18 11.8 0.0 2.0 1 0 0 1 1 1 0 AAA ATPase domain KaiC PF06745.8 KLO10242.1 - 0.082 12.0 0.1 0.22 10.6 0.1 1.6 1 0 0 1 1 1 0 KaiC AAA_17 PF13207.1 KLO10242.1 - 0.085 13.6 0.6 0.45 11.3 0.0 2.6 2 1 0 2 2 2 0 AAA domain Zot PF05707.7 KLO10242.1 - 0.11 11.9 0.1 1.8 8.0 0.0 2.3 2 0 0 2 2 2 0 Zonular occludens toxin (Zot) AAA_28 PF13521.1 KLO10242.1 - 0.14 12.1 1.0 0.53 10.2 0.4 2.0 1 1 1 2 2 2 0 AAA domain NACHT PF05729.7 KLO10243.1 - 1.2e-08 34.7 0.0 3.2e-08 33.4 0.0 1.7 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 KLO10243.1 - 0.00034 20.6 0.0 0.0035 17.3 0.0 2.6 1 1 0 1 1 1 1 AAA ATPase domain Med2 PF11214.3 KLO10243.1 - 0.08 12.9 0.7 0.19 11.7 0.0 2.0 2 0 0 2 2 2 0 Mediator complex subunit 2 DUF2153 PF09921.4 KLO10244.1 - 0.044 13.3 0.0 0.073 12.6 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2153) DUF572 PF04502.8 KLO10245.1 - 2e-57 194.8 0.8 2.8e-57 194.4 0.6 1.2 1 0 0 1 1 1 1 Family of unknown function (DUF572) Ribosomal_S10 PF00338.17 KLO10246.1 - 8.1e-24 83.3 0.7 9.6e-24 83.0 0.5 1.1 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e Pex14_N PF04695.8 KLO10247.1 - 3.4e-07 30.3 0.0 3.4e-07 30.3 0.0 2.8 3 1 0 3 3 3 1 Peroxisomal membrane anchor protein (Pex14p) conserved region Stork_head PF10264.4 KLO10247.1 - 0.012 15.7 0.0 0.027 14.6 0.0 1.6 1 0 0 1 1 1 0 Winged helix Storkhead-box1 domain MFS_1 PF07690.11 KLO10248.1 - 5.1e-34 117.5 9.1 5.1e-34 117.5 6.3 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily PAP2 PF01569.16 KLO10248.1 - 0.13 11.9 0.1 0.13 11.9 0.1 2.9 3 0 0 3 3 3 0 PAP2 superfamily PAP2_C PF14360.1 KLO10248.1 - 1.8 8.9 6.5 0.42 10.9 1.1 2.6 3 0 0 3 3 3 0 PAP2 superfamily C-terminal TFIIA PF03153.8 KLO10249.1 - 4.3 7.1 26.6 0.26 11.1 5.2 2.4 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit NPR3 PF03666.8 KLO10249.1 - 9.4 4.6 10.3 22 3.4 7.1 1.6 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 DUF4175 PF13779.1 KLO10250.1 - 1.1 6.8 6.0 1.2 6.7 4.2 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Glyco_hydro_7 PF00840.15 KLO10251.1 - 2.9e-211 701.4 23.5 3.7e-211 701.0 16.3 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 7 CBM_1 PF00734.13 KLO10251.1 - 3.1e-12 45.9 13.4 3.1e-12 45.9 9.3 4.3 3 1 0 3 3 3 1 Fungal cellulose binding domain p450 PF00067.17 KLO10252.1 - 3.3e-72 243.4 0.0 4.1e-72 243.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 KLO10253.1 - 6.6e-42 143.5 0.0 7.4e-42 143.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF2647 PF10839.3 KLO10255.1 - 0.076 13.0 0.5 0.3 11.1 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2647) UBN2 PF14223.1 KLO10257.1 - 0.0097 15.6 0.0 0.013 15.3 0.0 1.2 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type UBN2_2 PF14227.1 KLO10257.1 - 0.012 15.1 0.0 0.021 14.3 0.0 1.4 1 1 0 1 1 1 0 gag-polypeptide of LTR copia-type CbiQ PF02361.11 KLO10257.1 - 0.098 12.2 0.0 0.098 12.2 0.0 1.1 1 0 0 1 1 1 0 Cobalt transport protein K_trans PF02705.11 KLO10263.1 - 2.2e-175 584.0 10.5 2.7e-175 583.7 7.3 1.1 1 0 0 1 1 1 1 K+ potassium transporter p450 PF00067.17 KLO10267.1 - 2.2e-67 227.6 0.0 5.4e-67 226.3 0.0 1.5 1 1 0 1 1 1 1 Cytochrome P450 AChE_tetra PF08674.5 KLO10268.1 - 1.7 8.2 4.7 19 4.8 0.2 2.6 2 0 0 2 2 2 0 Acetylcholinesterase tetramerisation domain OPT PF03169.10 KLO10272.1 - 2.6e-190 633.9 61.9 3e-190 633.7 42.9 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein OPT PF03169.10 KLO10273.1 - 2.4e-183 610.9 57.7 2.8e-166 554.6 32.5 2.0 1 1 1 2 2 2 2 OPT oligopeptide transporter protein p450 PF00067.17 KLO10278.1 - 4.1e-70 236.5 0.0 9.4e-70 235.3 0.0 1.4 1 1 0 1 1 1 1 Cytochrome P450 OPT PF03169.10 KLO10280.1 - 7.6e-191 635.7 63.5 8.6e-191 635.5 44.0 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein RVP_2 PF08284.6 KLO10284.1 - 5.1e-09 36.1 0.0 6.7e-09 35.7 0.0 1.1 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.1 KLO10284.1 - 1.5e-05 25.4 0.0 2.6e-05 24.6 0.0 1.4 2 0 0 2 2 2 1 Aspartyl protease Asp_protease PF09668.5 KLO10284.1 - 0.0017 17.8 0.1 0.0026 17.3 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease Peptidase_A2B PF12384.3 KLO10284.1 - 0.034 13.4 0.0 0.05 12.9 0.0 1.2 1 0 0 1 1 1 0 Ty3 transposon peptidase DUF641 PF04859.7 KLO10286.1 - 0.036 13.8 0.4 0.078 12.7 0.3 1.5 1 0 0 1 1 1 0 Plant protein of unknown function (DUF641) ADH_zinc_N PF00107.21 KLO10292.1 - 1.5e-17 63.3 0.0 2.9e-17 62.4 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KLO10292.1 - 1e-10 41.2 0.0 5.2e-10 39.0 0.0 2.0 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 KLO10292.1 - 8e-07 29.9 0.0 1.8e-06 28.8 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase THF_DHG_CYH_C PF02882.14 KLO10292.1 - 0.032 13.2 0.0 0.069 12.2 0.0 1.5 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain HHH_8 PF14716.1 KLO10294.1 - 0.051 13.7 0.0 0.1 12.7 0.0 1.5 1 0 0 1 1 1 0 Helix-hairpin-helix domain DUF3185 PF11381.3 KLO10297.1 - 0.15 11.7 0.0 19 5.1 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3185) VIGSSK PF14773.1 KLO10297.1 - 1.3 9.0 4.2 1.2 9.0 0.1 2.7 3 0 0 3 3 3 0 Helicase-associated putative binding domain, C-terminal Sina PF03145.11 KLO10298.1 - 0.029 14.0 0.1 0.13 11.9 0.1 1.8 1 1 1 2 2 2 0 Seven in absentia protein family KilA-N PF04383.8 KLO10302.1 - 0.01 15.4 0.1 0.014 14.9 0.1 1.2 1 0 0 1 1 1 0 KilA-N domain FAR1 PF03101.10 KLO10303.1 - 9.1e-08 32.5 1.9 1.5e-07 31.7 1.3 1.3 1 0 0 1 1 1 1 FAR1 DNA-binding domain adh_short PF00106.20 KLO10314.1 - 4.6e-22 78.6 0.5 6.1e-22 78.3 0.4 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KLO10314.1 - 9.2e-09 35.4 0.1 1.4e-08 34.7 0.1 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KLO10314.1 - 1.5e-08 34.4 0.4 2.2e-08 33.9 0.3 1.2 1 0 0 1 1 1 1 KR domain TRAP_beta PF05753.9 KLO10314.1 - 0.028 13.5 0.1 0.49 9.5 0.0 2.1 1 1 1 2 2 2 0 Translocon-associated protein beta (TRAPB) NAD_binding_10 PF13460.1 KLO10314.1 - 0.057 13.4 0.1 0.12 12.3 0.0 1.5 1 1 0 1 1 1 0 NADH(P)-binding DUF3870 PF12986.2 KLO10314.1 - 0.13 12.5 0.1 19 5.5 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3870) GIT_SHD PF08518.6 KLO10315.1 - 1.2e-24 85.3 0.9 7.8e-14 50.7 0.5 2.7 2 0 0 2 2 2 2 Spa2 homology domain (SHD) of GIT Spectrin PF00435.16 KLO10315.1 - 0.014 15.6 14.8 0.26 11.6 2.1 3.8 2 1 0 3 3 3 0 Spectrin repeat GAS PF13851.1 KLO10315.1 - 0.053 12.6 17.4 1.5 7.9 1.0 3.3 3 0 0 3 3 3 0 Growth-arrest specific micro-tubule binding Tweety PF04906.8 KLO10315.1 - 0.17 10.2 2.0 1.5 7.1 0.0 2.6 2 0 0 2 2 2 0 Tweety CENP-F_leu_zip PF10473.4 KLO10315.1 - 0.49 10.2 27.5 0.2 11.5 8.9 3.0 3 0 0 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 TMF_DNA_bd PF12329.3 KLO10315.1 - 0.56 10.0 28.8 0.79 9.5 0.3 4.4 4 1 0 4 4 4 0 TATA element modulatory factor 1 DNA binding Sipho_Gp157 PF05565.6 KLO10315.1 - 1.1 8.7 12.6 0.058 12.9 1.1 3.2 2 1 0 3 3 3 0 Siphovirus Gp157 Spc7 PF08317.6 KLO10315.1 - 3.7 6.1 25.3 0.26 9.9 7.3 2.9 2 1 1 3 3 3 0 Spc7 kinetochore protein ADIP PF11559.3 KLO10315.1 - 5.2 6.9 25.0 2.5 7.9 2.8 3.7 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding IncA PF04156.9 KLO10315.1 - 6.5 6.3 32.7 7 6.1 12.0 3.4 2 1 1 3 3 3 0 IncA protein BLOC1_2 PF10046.4 KLO10315.1 - 8.9 6.5 12.6 1.4 9.0 2.0 3.3 2 1 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 AAA PF00004.24 KLO10316.1 - 1.9e-61 206.0 0.0 1.7e-43 147.9 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) PEX-1N PF09262.6 KLO10316.1 - 2.9e-24 84.9 0.3 8.8e-24 83.3 0.2 1.9 1 0 0 1 1 1 1 Peroxisome biogenesis factor 1, N-terminal AAA_16 PF13191.1 KLO10316.1 - 1.9e-13 50.8 4.8 7.2e-07 29.3 0.3 4.1 2 2 1 3 3 3 2 AAA ATPase domain RuvB_N PF05496.7 KLO10316.1 - 2.6e-08 33.2 0.0 0.0016 17.5 0.0 2.5 2 0 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus AAA_17 PF13207.1 KLO10316.1 - 1.5e-07 32.2 0.0 0.0028 18.4 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.1 KLO10316.1 - 4.7e-07 30.0 2.3 0.029 14.5 0.3 4.0 2 2 0 2 2 2 2 AAA domain NACHT PF05729.7 KLO10316.1 - 6.1e-07 29.2 2.9 0.00067 19.3 0.4 3.7 3 1 0 3 3 3 1 NACHT domain AAA_18 PF13238.1 KLO10316.1 - 1.3e-06 28.6 0.0 0.094 13.0 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_2 PF07724.9 KLO10316.1 - 1.5e-06 28.2 0.0 0.03 14.2 0.0 3.2 3 1 0 3 3 3 2 AAA domain (Cdc48 subfamily) TIP49 PF06068.8 KLO10316.1 - 2e-06 26.7 0.1 0.037 12.7 0.0 2.2 2 0 0 2 2 2 2 TIP49 C-terminus AAA_5 PF07728.9 KLO10316.1 - 2e-06 27.5 0.3 0.04 13.6 0.0 3.6 3 2 0 3 3 2 2 AAA domain (dynein-related subfamily) AAA_19 PF13245.1 KLO10316.1 - 2.3e-06 27.2 0.1 0.0075 15.9 0.0 2.8 2 0 0 2 2 2 2 Part of AAA domain AAA_14 PF13173.1 KLO10316.1 - 8e-06 25.7 0.0 0.11 12.3 0.0 2.4 2 0 0 2 2 2 2 AAA domain NB-ARC PF00931.17 KLO10316.1 - 1.4e-05 24.0 0.0 0.024 13.4 0.0 2.3 2 0 0 2 2 2 2 NB-ARC domain RNA_helicase PF00910.17 KLO10316.1 - 3.2e-05 24.0 0.0 0.32 11.2 0.0 2.6 2 0 0 2 2 2 2 RNA helicase AAA_25 PF13481.1 KLO10316.1 - 6.5e-05 22.4 4.7 2.3 7.5 0.1 4.8 2 2 2 5 5 5 1 AAA domain Parvo_NS1 PF01057.12 KLO10316.1 - 0.00011 21.2 0.0 0.077 11.8 0.0 2.3 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 Mg_chelatase PF01078.16 KLO10316.1 - 0.00011 21.4 0.6 0.76 8.8 0.0 3.4 4 0 0 4 4 3 2 Magnesium chelatase, subunit ChlI DUF2075 PF09848.4 KLO10316.1 - 0.00012 21.2 0.0 0.12 11.3 0.0 2.5 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2075) PhoH PF02562.11 KLO10316.1 - 0.00013 21.2 0.0 0.03 13.5 0.0 2.3 2 0 0 2 2 2 1 PhoH-like protein AAA_33 PF13671.1 KLO10316.1 - 0.0002 21.2 0.0 0.032 14.0 0.0 2.8 2 0 0 2 2 2 1 AAA domain Arch_ATPase PF01637.13 KLO10316.1 - 0.00034 20.3 2.5 0.19 11.4 0.0 4.0 3 2 1 4 4 4 1 Archaeal ATPase Zeta_toxin PF06414.7 KLO10316.1 - 0.00038 19.6 0.0 0.25 10.4 0.0 2.5 2 0 0 2 2 2 1 Zeta toxin Sigma54_activat PF00158.21 KLO10316.1 - 0.00062 19.2 0.1 0.17 11.3 0.0 2.6 2 1 0 2 2 2 1 Sigma-54 interaction domain IstB_IS21 PF01695.12 KLO10316.1 - 0.0011 18.4 0.1 0.52 9.6 0.0 2.5 2 0 0 2 2 2 1 IstB-like ATP binding protein Sigma54_activ_2 PF14532.1 KLO10316.1 - 0.0021 18.1 0.1 4 7.5 0.0 2.9 3 0 0 3 3 2 0 Sigma-54 interaction domain AAA_3 PF07726.6 KLO10316.1 - 0.0027 17.3 0.0 0.79 9.3 0.0 2.5 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.1 KLO10316.1 - 0.0037 16.8 1.8 0.023 14.2 0.0 2.6 3 0 0 3 3 2 1 AAA domain Viral_helicase1 PF01443.13 KLO10316.1 - 0.0044 16.5 0.9 0.35 10.3 0.0 3.1 4 0 0 4 4 4 1 Viral (Superfamily 1) RNA helicase AAA_28 PF13521.1 KLO10316.1 - 0.0046 16.9 0.0 1.6 8.7 0.0 2.6 2 0 0 2 2 2 1 AAA domain NTPase_1 PF03266.10 KLO10316.1 - 0.0052 16.5 0.2 0.41 10.3 0.0 2.4 2 0 0 2 2 2 1 NTPase AAA_24 PF13479.1 KLO10316.1 - 0.0054 16.3 0.5 2.8 7.4 0.1 2.4 2 0 0 2 2 2 1 AAA domain KaiC PF06745.8 KLO10316.1 - 0.0082 15.2 0.7 2.9 6.9 0.0 3.0 2 1 1 3 3 3 1 KaiC DUF815 PF05673.8 KLO10316.1 - 0.009 14.9 0.0 0.85 8.4 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF815) KTI12 PF08433.5 KLO10316.1 - 0.01 15.0 1.4 10 5.2 0.0 3.2 3 0 0 3 3 3 0 Chromatin associated protein KTI12 ABC_tran PF00005.22 KLO10316.1 - 0.016 15.5 0.1 4.9 7.4 0.0 3.2 3 0 0 3 3 2 0 ABC transporter T2SE PF00437.15 KLO10316.1 - 0.024 13.5 0.1 1.2 7.9 0.1 2.3 2 0 0 2 2 2 0 Type II/IV secretion system protein SKI PF01202.17 KLO10316.1 - 0.034 14.0 0.1 0.82 9.5 0.0 2.5 2 0 0 2 2 2 0 Shikimate kinase UPF0079 PF02367.12 KLO10316.1 - 0.041 13.5 0.1 8.2 6.0 0.0 2.3 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 Cytidylate_kin2 PF13189.1 KLO10316.1 - 0.051 13.4 0.0 0.28 11.0 0.0 2.1 2 0 0 2 2 2 0 Cytidylate kinase-like family Transgly PF00912.17 KLO10316.1 - 0.073 12.3 0.0 0.15 11.3 0.0 1.4 1 0 0 1 1 1 0 Transglycosylase AAA_29 PF13555.1 KLO10316.1 - 0.12 11.8 0.3 1.3 8.6 0.2 2.3 2 0 0 2 2 2 0 P-loop containing region of AAA domain PduV-EutP PF10662.4 KLO10316.1 - 0.17 11.3 0.2 13 5.2 0.0 2.9 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation APS_kinase PF01583.15 KLO10316.1 - 0.18 11.4 0.4 4.4 6.9 0.1 2.8 2 1 1 3 3 2 0 Adenylylsulphate kinase BcrAD_BadFG PF01869.15 KLO10317.1 - 4e-14 52.5 0.0 1.5e-13 50.6 0.0 1.9 1 1 0 1 1 1 1 BadF/BadG/BcrA/BcrD ATPase family Glyco_transf_49 PF13896.1 KLO10318.1 - 6.5e-38 130.6 0.0 7.9e-32 110.6 0.0 2.1 1 1 1 2 2 2 2 Glycosyl-transferase for dystroglycan Glyco_tranf_2_2 PF10111.4 KLO10318.1 - 0.06 12.4 0.0 0.12 11.4 0.0 1.5 1 0 0 1 1 1 0 Glycosyltransferase like family 2 CTP_transf_2 PF01467.21 KLO10319.1 - 7.9e-25 87.7 0.0 1.1e-24 87.3 0.0 1.2 1 0 0 1 1 1 1 Cytidylyltransferase E1-E2_ATPase PF00122.15 KLO10320.1 - 1.9e-21 76.1 0.0 5.2e-21 74.7 0.0 1.7 1 0 0 1 1 1 1 E1-E2 ATPase HAD PF12710.2 KLO10320.1 - 2.6e-17 63.6 0.1 6.8e-17 62.2 0.0 1.8 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 KLO10320.1 - 9.1e-15 55.6 0.2 1.2e-13 51.9 0.1 2.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 KLO10320.1 - 3.3e-13 49.4 0.0 9.4e-13 47.9 0.0 1.7 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 KLO10320.1 - 0.0029 17.2 0.1 0.011 15.3 0.0 1.9 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Abhydrolase_6 PF12697.2 KLO10321.1 - 2.5e-08 34.0 0.2 3.6e-08 33.5 0.1 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KLO10321.1 - 7.5e-08 32.2 0.0 2e-07 30.8 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.8 KLO10321.1 - 0.0012 18.5 0.0 0.0024 17.5 0.0 1.5 1 0 0 1 1 1 1 PGAP1-like protein Thioesterase PF00975.15 KLO10321.1 - 0.031 14.4 0.0 0.06 13.5 0.0 1.6 1 0 0 1 1 1 0 Thioesterase domain Abhydrolase_3 PF07859.8 KLO10321.1 - 0.13 11.8 0.0 0.22 11.0 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold DUF2974 PF11187.3 KLO10321.1 - 0.17 11.2 0.0 0.28 10.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Cornichon PF03311.9 KLO10322.1 - 6.2e-49 165.3 7.7 6.9e-49 165.2 5.3 1.0 1 0 0 1 1 1 1 Cornichon protein DUF1634 PF07843.6 KLO10322.1 - 0.21 11.2 0.0 0.21 11.2 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1634) ABC_membrane PF00664.18 KLO10323.1 - 3.1e-46 158.0 4.8 4.2e-46 157.5 3.3 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.22 KLO10323.1 - 1.1e-31 109.9 0.0 2.6e-31 108.7 0.0 1.7 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.14 KLO10323.1 - 3e-06 26.6 0.1 0.003 16.8 0.0 2.4 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 KLO10323.1 - 0.00015 21.8 0.1 0.05 13.5 0.0 2.2 1 1 1 2 2 2 2 AAA domain DUF87 PF01935.12 KLO10323.1 - 0.021 14.6 0.1 0.063 13.0 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function DUF87 AAA_29 PF13555.1 KLO10323.1 - 0.024 14.1 0.1 0.065 12.7 0.1 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain Zeta_toxin PF06414.7 KLO10323.1 - 0.047 12.7 0.0 0.15 11.1 0.0 1.8 2 0 0 2 2 2 0 Zeta toxin DUF258 PF03193.11 KLO10323.1 - 0.17 11.0 0.0 0.3 10.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_16 PF13191.1 KLO10323.1 - 0.28 11.1 4.8 0.21 11.5 0.5 2.8 3 1 0 3 3 3 0 AAA ATPase domain Transcript_VP30 PF11507.3 KLO10324.1 - 0.074 12.8 0.0 0.13 12.1 0.0 1.3 1 0 0 1 1 1 0 Ebola virus-specific transcription factor VP30 Cornichon PF03311.9 KLO10326.1 - 1.1e-50 171.0 6.9 1.2e-50 170.8 4.8 1.0 1 0 0 1 1 1 1 Cornichon protein UbiA PF01040.13 KLO10326.1 - 0.011 14.9 4.0 0.014 14.6 2.8 1.1 1 0 0 1 1 1 0 UbiA prenyltransferase family DUF1634 PF07843.6 KLO10326.1 - 0.06 12.9 0.7 0.12 11.9 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1634) Oxidored_q3 PF00499.15 KLO10326.1 - 7.2 6.3 11.5 16 5.2 8.0 1.5 1 1 0 1 1 1 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 Pro_racemase PF05544.6 KLO10327.1 - 7.6e-62 209.0 0.0 2.4e-36 125.1 0.0 2.6 2 1 0 2 2 2 2 Proline racemase An_peroxidase PF03098.10 KLO10329.1 - 4.8e-66 223.2 0.0 1.1e-63 215.4 0.0 2.5 1 1 0 1 1 1 1 Animal haem peroxidase p450 PF00067.17 KLO10329.1 - 0.0013 17.3 0.0 0.0056 15.2 0.0 1.9 3 0 0 3 3 3 1 Cytochrome P450 ABC_membrane PF00664.18 KLO10329.1 - 0.07 12.5 0.2 0.11 11.8 0.2 1.2 1 0 0 1 1 1 0 ABC transporter transmembrane region F_bP_aldolase PF01116.15 KLO10330.1 - 1.4e-99 332.8 0.0 1.5e-99 332.7 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II Torsin PF06309.6 KLO10330.1 - 0.086 12.7 0.0 0.15 11.9 0.0 1.3 1 0 0 1 1 1 0 Torsin GFA PF04828.9 KLO10331.1 - 7.9e-08 32.1 1.6 7.9e-08 32.1 1.1 1.7 2 0 0 2 2 2 1 Glutathione-dependent formaldehyde-activating enzyme Kunitz_legume PF00197.13 KLO10331.1 - 0.12 11.9 1.5 0.13 11.7 1.1 1.2 1 0 0 1 1 1 0 Trypsin and protease inhibitor Cytochrome_C554 PF13435.1 KLO10331.1 - 0.35 10.9 8.1 0.47 10.4 5.6 1.2 1 0 0 1 1 1 0 Cytochrome c554 and c-prime Cys_rich_CWC PF14375.1 KLO10331.1 - 0.49 10.3 6.5 0.2 11.6 1.4 2.1 2 0 0 2 2 2 0 Cysteine-rich CWC GFA PF04828.9 KLO10332.1 - 9e-09 35.1 0.4 9e-09 35.1 0.3 1.9 2 0 0 2 2 2 1 Glutathione-dependent formaldehyde-activating enzyme F-box-like PF12937.2 KLO10335.1 - 0.0015 18.1 0.0 0.015 15.0 0.0 2.7 2 1 0 2 2 2 1 F-box-like COX7C PF02935.11 KLO10337.1 - 8.8e-15 54.2 0.5 1.1e-14 53.9 0.4 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIIc Solute_trans_a PF03619.11 KLO10338.1 - 3e-79 266.1 11.2 3.8e-79 265.8 7.8 1.1 1 0 0 1 1 1 1 Organic solute transporter Ostalpha DPM3 PF08285.6 KLO10338.1 - 1.8 8.4 9.8 0.035 13.9 0.9 2.4 2 1 0 2 2 2 0 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) p450 PF00067.17 KLO10339.1 - 1.2e-63 215.2 0.0 8.6e-63 212.4 0.0 2.0 1 1 0 1 1 1 1 Cytochrome P450 Ribosomal_L37 PF08561.5 KLO10340.1 - 0.11 12.0 0.1 0.21 11.1 0.1 1.4 1 0 0 1 1 1 0 Mitochondrial ribosomal protein L37 K167R PF08065.7 KLO10345.1 - 0.1 12.6 1.2 0.23 11.5 0.8 1.5 1 0 0 1 1 1 0 K167R (NUC007) repeat ubiquitin PF00240.18 KLO10349.1 - 6.1e-05 22.3 1.5 0.057 12.8 0.0 2.8 2 0 0 2 2 2 2 Ubiquitin family Ubiquitin_2 PF14560.1 KLO10349.1 - 0.006 16.8 0.4 0.02 15.1 0.1 2.0 2 1 0 2 2 2 1 Ubiquitin-like domain p450 PF00067.17 KLO10351.1 - 4.4e-67 226.5 0.0 5.4e-67 226.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 TFIIB PF00382.14 KLO10354.1 - 5e-36 122.3 1.8 1.3e-17 63.3 0.0 2.4 2 0 0 2 2 2 2 Transcription factor TFIIB repeat BRF1 PF07741.8 KLO10354.1 - 1.7e-22 79.4 2.6 1.7e-22 79.4 1.8 3.2 3 0 0 3 3 3 1 Brf1-like TBP-binding domain Cyclin_N PF00134.18 KLO10354.1 - 8.6e-08 31.7 0.6 0.0011 18.4 0.2 2.3 2 0 0 2 2 2 2 Cyclin, N-terminal domain TF_Zn_Ribbon PF08271.7 KLO10354.1 - 1.9e-07 30.2 3.7 4.4e-07 29.1 2.6 1.7 1 0 0 1 1 1 1 TFIIB zinc-binding A2L_zn_ribbon PF08792.5 KLO10354.1 - 0.08 12.4 1.7 0.15 11.5 1.2 1.4 1 0 0 1 1 1 0 A2L zinc ribbon domain RRN7 PF11781.3 KLO10354.1 - 1.3 8.6 6.5 0.098 12.1 1.0 1.8 2 0 0 2 2 2 0 RNA polymerase I-specific transcription initiation factor Rrn7 Solute_trans_a PF03619.11 KLO10355.1 - 3.8e-48 164.1 9.1 7.5e-46 156.6 3.9 2.0 2 0 0 2 2 2 2 Organic solute transporter Ostalpha DUF2763 PF10961.3 KLO10356.1 - 0.04 14.3 0.2 0.04 14.3 0.1 2.3 1 1 0 2 2 2 0 Protein of unknown function (DUF2763) AA_permease_2 PF13520.1 KLO10357.1 - 8.5e-56 189.2 47.1 2.8e-30 105.1 19.4 2.0 1 1 1 2 2 2 2 Amino acid permease AA_permease PF00324.16 KLO10357.1 - 1.7e-13 49.7 41.6 6.1e-08 31.4 13.0 2.5 1 1 1 2 2 2 2 Amino acid permease AA_permease_2 PF13520.1 KLO10358.1 - 3e-70 236.9 55.2 3.4e-70 236.7 38.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 KLO10358.1 - 3.1e-16 58.7 47.3 5.1e-16 58.0 32.8 1.3 1 1 0 1 1 1 1 Amino acid permease Bromodomain PF00439.20 KLO10359.1 - 6.4e-22 77.2 0.0 1.6e-21 76.0 0.0 1.6 1 0 0 1 1 1 1 Bromodomain Homeobox PF00046.24 KLO10361.1 - 2.4e-18 65.5 3.6 4.4e-18 64.6 2.5 1.4 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 KLO10361.1 - 8.5e-05 22.1 0.2 8.5e-05 22.1 0.1 3.2 4 0 0 4 4 4 1 Homeobox KN domain MRP-L20 PF12824.2 KLO10361.1 - 0.033 14.1 1.0 0.033 14.1 0.7 2.4 3 0 0 3 3 3 0 Mitochondrial ribosomal protein subunit L20 Homez PF11569.3 KLO10361.1 - 0.1 11.6 0.1 0.19 10.7 0.0 1.4 1 0 0 1 1 1 0 Homeodomain leucine-zipper encoding, Homez HA PF03457.9 KLO10361.1 - 3 8.0 5.2 1.7 8.8 0.7 2.4 1 1 1 2 2 2 0 Helicase associated domain Fez1 PF06818.10 KLO10362.1 - 0.12 12.4 1.2 0.2 11.6 0.8 1.3 1 0 0 1 1 1 0 Fez1 zf-C3HC4 PF00097.20 KLO10363.1 - 1.5e-10 40.5 8.9 2.7e-10 39.7 6.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KLO10363.1 - 2.1e-09 37.0 10.4 4.5e-09 35.9 7.2 1.6 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 KLO10363.1 - 3.1e-09 36.6 9.8 3.1e-09 36.6 6.8 1.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KLO10363.1 - 1.5e-07 30.9 5.2 2.4e-07 30.3 3.6 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KLO10363.1 - 3.3e-06 26.7 9.1 5.2e-06 26.0 6.3 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.2 KLO10363.1 - 1.8e-05 24.7 9.7 1.8e-05 24.7 6.7 2.2 2 1 0 2 2 2 1 RING-H2 zinc finger zf-C3HC4_4 PF15227.1 KLO10363.1 - 3.6e-05 23.5 8.8 6.9e-05 22.6 6.1 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 KLO10363.1 - 0.0016 18.1 4.6 0.0031 17.1 3.2 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_6 PF14835.1 KLO10363.1 - 0.11 12.3 4.1 0.2 11.4 2.8 1.4 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-RING_4 PF14570.1 KLO10363.1 - 0.23 11.0 7.1 0.63 9.6 5.0 1.7 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-Apc11 PF12861.2 KLO10363.1 - 0.34 10.7 8.4 0.29 10.9 3.9 2.2 2 1 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-P11 PF03854.9 KLO10363.1 - 1.9 8.0 7.4 4.7 6.7 5.2 1.6 1 1 0 1 1 1 0 P-11 zinc finger IBR PF01485.16 KLO10363.1 - 4.5 7.2 9.1 9.5 6.1 5.1 2.3 2 1 0 2 2 2 0 IBR domain Acid_PPase PF12689.2 KLO10364.1 - 9.5e-59 197.8 0.0 1.1e-58 197.5 0.0 1.0 1 0 0 1 1 1 1 Acid Phosphatase HAD_2 PF13419.1 KLO10364.1 - 0.027 14.6 2.9 0.12 12.6 0.3 2.9 2 1 0 2 2 2 0 Haloacid dehalogenase-like hydrolase RHH_3 PF12651.2 KLO10364.1 - 0.037 13.7 0.1 1 9.1 0.0 2.3 2 0 0 2 2 2 0 Ribbon-helix-helix domain Sec7_N PF12783.2 KLO10365.1 - 1.2e-36 125.6 2.3 4e-36 123.9 0.0 2.9 2 1 0 2 2 2 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF1981 PF09324.5 KLO10365.1 - 4.2e-06 26.1 2.2 0.033 13.7 0.0 4.8 4 0 0 4 4 4 2 Domain of unknown function (DUF1981) DUF1383 PF07134.6 KLO10365.1 - 0.12 11.3 0.0 0.22 10.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1383) CBFD_NFYB_HMF PF00808.18 KLO10366.1 - 4.1e-08 33.1 0.1 6.9e-08 32.4 0.0 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone BUD22 PF09073.5 KLO10366.1 - 0.023 13.7 18.2 0.025 13.6 12.6 1.1 1 0 0 1 1 1 0 BUD22 DUF2183 PF09949.4 KLO10366.1 - 0.13 12.1 0.0 0.23 11.4 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2183) Gti1_Pac2 PF09729.4 KLO10366.1 - 0.33 10.7 2.4 0.19 11.5 0.3 1.7 2 0 0 2 2 2 0 Gti1/Pac2 family Cobl PF09469.5 KLO10367.1 - 1.3 9.0 4.1 2.3 8.2 2.9 1.4 1 0 0 1 1 1 0 Cordon-bleu ubiquitin-like domain YL1 PF05764.8 KLO10367.1 - 8.8 5.8 12.4 1.2 8.7 5.8 1.5 1 1 0 1 1 1 0 YL1 nuclear protein FmdA_AmdA PF03069.10 KLO10368.1 - 3e-53 180.8 0.5 1.4e-26 93.1 0.2 2.1 1 1 1 2 2 2 2 Acetamidase/Formamidase family DUF3844 PF12955.2 KLO10369.1 - 0.09 12.8 0.4 0.12 12.4 0.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3844) Phage_XkdX PF09693.5 KLO10370.1 - 0.039 13.4 0.0 0.083 12.4 0.0 1.5 1 0 0 1 1 1 0 Phage uncharacterised protein (Phage_XkdX) Transposase_21 PF02992.9 KLO10373.1 - 3.3e-10 39.4 0.0 5.5e-10 38.7 0.0 1.4 1 0 0 1 1 1 1 Transposase family tnp2 DUF1258 PF06869.7 KLO10373.1 - 3.6e-05 22.9 0.0 5.5e-05 22.3 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1258) SNF2_N PF00176.18 KLO10374.1 - 1.3e-68 231.0 0.0 2.1e-67 227.0 0.0 2.5 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 KLO10374.1 - 2.9e-15 55.8 0.0 1.1e-14 54.0 0.0 2.1 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 KLO10374.1 - 1.1e-06 28.6 0.0 0.012 15.3 0.0 2.8 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit HDA2-3 PF11496.3 KLO10374.1 - 1.3e-06 27.4 0.0 2.8e-06 26.3 0.0 1.5 1 0 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 DNA_mis_repair PF01119.14 KLO10375.1 - 5.9e-18 64.4 0.0 1.6e-17 63.0 0.0 1.7 2 0 0 2 2 2 1 DNA mismatch repair protein, C-terminal domain HATPase_c PF02518.21 KLO10375.1 - 1.8e-13 50.1 0.0 3.9e-13 49.0 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.1 KLO10375.1 - 1.1e-12 47.7 0.1 2.2e-12 46.8 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Microvir_H PF04687.7 KLO10375.1 - 0.13 11.2 0.3 0.21 10.5 0.2 1.3 1 0 0 1 1 1 0 Microvirus H protein (pilot protein) MutL_C PF08676.6 KLO10376.1 - 5.7e-21 74.6 0.2 1.2e-20 73.6 0.2 1.5 1 1 0 1 1 1 1 MutL C terminal dimerisation domain F-box-like PF12937.2 KLO10377.1 - 9.6e-05 22.0 1.9 0.0002 21.0 0.6 2.1 2 0 0 2 2 2 1 F-box-like Rhodanese PF00581.15 KLO10378.1 - 8.2e-08 32.5 0.0 1.4e-07 31.8 0.0 1.4 1 0 0 1 1 1 1 Rhodanese-like domain HMA PF00403.21 KLO10379.1 - 0.0013 18.8 0.7 0.0033 17.5 0.5 1.7 1 1 0 1 1 1 1 Heavy-metal-associated domain Tcp11 PF05794.8 KLO10382.1 - 5.9e-23 81.2 0.8 1.6e-14 53.4 0.1 2.6 2 1 0 2 2 2 2 T-complex protein 11 Mrr_N PF14338.1 KLO10382.1 - 0.12 12.4 0.4 0.46 10.6 0.0 2.2 2 0 0 2 2 2 0 Mrr N-terminal domain Prenyltrans PF00432.16 KLO10383.1 - 3.8e-58 192.6 3.0 3.7e-12 45.5 0.0 6.1 6 0 0 6 6 6 5 Prenyltransferase and squalene oxidase repeat Prenyltrans_2 PF13249.1 KLO10383.1 - 6.5e-30 103.8 0.0 1.3e-12 48.1 0.0 3.9 1 1 3 4 4 4 4 Prenyltransferase-like Prenyltrans_1 PF13243.1 KLO10383.1 - 7.6e-08 32.3 0.0 2.5e-05 24.2 0.0 3.3 1 1 2 3 3 3 2 Prenyltransferase-like 2OG-FeII_Oxy_2 PF13532.1 KLO10385.1 - 6e-28 97.9 0.0 7.4e-28 97.7 0.0 1.1 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.15 KLO10385.1 - 6.6e-05 23.1 0.2 0.00011 22.4 0.1 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DUF4175 PF13779.1 KLO10385.1 - 0.022 12.4 0.0 0.029 12.0 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) TPR_11 PF13414.1 KLO10386.1 - 9.3e-54 178.9 13.3 2.5e-16 59.0 0.0 7.1 3 2 3 7 7 7 6 TPR repeat TPR_1 PF00515.23 KLO10386.1 - 2.1e-38 128.3 14.0 1.9e-06 27.2 0.0 10.8 10 1 0 10 10 10 8 Tetratricopeptide repeat TPR_2 PF07719.12 KLO10386.1 - 1.9e-37 124.1 14.0 0.00016 21.3 0.1 11.2 11 0 0 11 11 11 7 Tetratricopeptide repeat TPR_16 PF13432.1 KLO10386.1 - 2.8e-29 101.1 11.0 7.2e-07 29.7 0.0 7.4 5 2 2 7 7 7 3 Tetratricopeptide repeat TPR_12 PF13424.1 KLO10386.1 - 1e-22 79.8 16.3 0.00049 19.9 0.0 7.4 4 2 3 7 7 7 6 Tetratricopeptide repeat TPR_17 PF13431.1 KLO10386.1 - 7.8e-21 72.4 3.5 0.023 14.8 0.0 8.5 9 0 0 9 9 8 4 Tetratricopeptide repeat TPR_19 PF14559.1 KLO10386.1 - 6.1e-18 64.9 12.9 2.1e-05 24.7 1.3 5.9 5 1 0 6 6 5 3 Tetratricopeptide repeat TPR_14 PF13428.1 KLO10386.1 - 3.2e-17 61.4 17.4 0.00054 20.3 0.0 8.8 6 3 4 10 10 9 5 Tetratricopeptide repeat TPR_7 PF13176.1 KLO10386.1 - 2.2e-16 58.2 7.9 0.0056 16.3 0.1 9.1 8 1 1 9 9 9 4 Tetratricopeptide repeat Apc3 PF12895.2 KLO10386.1 - 3.9e-16 58.9 5.8 0.00029 20.9 0.0 4.5 4 0 0 4 4 4 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.1 KLO10386.1 - 2.2e-14 53.0 8.8 0.0011 18.7 0.0 5.7 3 2 1 5 5 5 4 Tetratricopeptide repeat TPR_8 PF13181.1 KLO10386.1 - 1.6e-13 49.3 12.1 0.059 13.1 0.0 9.1 8 2 2 10 10 9 3 Tetratricopeptide repeat TPR_6 PF13174.1 KLO10386.1 - 4.8e-10 39.2 20.3 0.047 14.1 0.0 9.1 10 0 0 10 10 9 2 Tetratricopeptide repeat DUF3856 PF12968.2 KLO10386.1 - 1.2e-06 28.3 3.5 0.82 9.4 0.1 5.4 4 2 0 4 4 4 1 Domain of Unknown Function (DUF3856) Rapsyn_N PF10579.4 KLO10386.1 - 2.7e-05 23.8 0.1 0.11 12.3 0.0 3.9 4 0 0 4 4 4 1 Rapsyn N-terminal myristoylation and linker region SHNi-TPR PF10516.4 KLO10386.1 - 9.6e-05 21.5 6.5 0.44 9.8 0.0 5.7 6 0 0 6 6 6 1 SHNi-TPR TPR_20 PF14561.1 KLO10386.1 - 0.00031 20.7 17.7 0.09 12.9 1.0 5.9 5 2 3 8 8 6 2 Tetratricopeptide repeat Coatomer_E PF04733.9 KLO10386.1 - 0.00087 18.5 0.9 0.41 9.8 0.1 3.0 3 0 0 3 3 3 1 Coatomer epsilon subunit TPR_10 PF13374.1 KLO10386.1 - 0.00089 19.1 5.1 1.7 8.7 0.0 6.1 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_15 PF13429.1 KLO10386.1 - 0.0048 16.0 8.7 1.6 7.7 0.3 4.4 3 1 0 4 4 4 2 Tetratricopeptide repeat TPR_4 PF07721.9 KLO10386.1 - 0.046 14.1 0.2 2.2 8.9 0.0 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat Reovirus_cap PF00979.12 KLO10386.1 - 0.13 11.1 0.0 0.19 10.6 0.0 1.2 1 0 0 1 1 1 0 Reovirus outer capsid protein, Sigma 3 TPR_21 PF09976.4 KLO10386.1 - 0.22 11.4 16.7 0.64 9.9 0.6 5.0 4 1 1 5 5 5 0 Tetratricopeptide repeat Apc5 PF12862.2 KLO10386.1 - 0.25 11.1 10.6 0.25 11.1 0.3 4.2 5 2 0 5 5 4 0 Anaphase-promoting complex subunit 5 DUF3808 PF10300.4 KLO10386.1 - 4.9 5.6 9.0 4.9 5.6 0.1 3.1 2 1 2 4 4 4 0 Protein of unknown function (DUF3808) Rad60-SLD PF11976.3 KLO10387.1 - 2.7e-11 42.9 4.3 1.2e-08 34.5 0.4 2.4 2 1 0 2 2 2 2 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.18 KLO10387.1 - 5.7e-05 22.4 1.0 0.0011 18.3 0.1 2.2 2 0 0 2 2 2 1 Ubiquitin family CIA30 PF08547.7 KLO10387.1 - 0.091 12.6 0.1 0.11 12.3 0.1 1.1 1 0 0 1 1 1 0 Complex I intermediate-associated protein 30 (CIA30) tRNA-synt_1g PF09334.6 KLO10387.1 - 0.1 11.2 0.6 0.11 11.0 0.4 1.0 1 0 0 1 1 1 0 tRNA synthetases class I (M) ATG22 PF11700.3 KLO10388.1 - 3e-140 467.8 15.4 3.4e-140 467.7 10.6 1.0 1 0 0 1 1 1 1 Vacuole effluxer Atg22 like MFS_1 PF07690.11 KLO10388.1 - 6.6e-06 25.0 51.2 0.019 13.7 11.5 3.6 2 2 1 3 3 3 3 Major Facilitator Superfamily DUF4451 PF14616.1 KLO10389.1 - 8.2e-30 103.1 3.3 1e-29 102.8 2.3 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4451) EMP24_GP25L PF01105.19 KLO10390.1 - 2.8e-40 137.9 0.0 3.3e-40 137.7 0.0 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Herpes_UL49_5 PF05702.6 KLO10390.1 - 0.019 14.8 0.1 0.092 12.6 0.0 2.0 2 0 0 2 2 2 0 Herpesvirus UL49.5 envelope/tegument protein 2-Hacid_dh_C PF02826.14 KLO10391.1 - 2.2e-55 186.5 0.0 3.3e-55 185.9 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 KLO10391.1 - 9.4e-31 106.0 0.0 1.6e-30 105.3 0.0 1.4 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 KLO10391.1 - 2.8e-05 24.0 0.0 5.8e-05 22.9 0.0 1.5 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase IlvN PF07991.7 KLO10391.1 - 0.019 14.3 0.0 0.052 12.9 0.0 1.8 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, catalytic domain CHASE2 PF05226.6 KLO10391.1 - 0.047 12.9 0.0 0.075 12.2 0.0 1.3 1 0 0 1 1 1 0 CHASE2 domain PP2C PF00481.16 KLO10392.1 - 1.9e-08 34.0 0.0 0.00066 19.1 0.0 2.3 2 0 0 2 2 2 2 Protein phosphatase 2C PP2C_2 PF13672.1 KLO10392.1 - 1.8e-06 27.5 0.1 5.5e-06 25.9 0.0 1.9 2 0 0 2 2 2 1 Protein phosphatase 2C SpoIIE PF07228.7 KLO10392.1 - 7.7e-06 25.7 0.0 2.6e-05 24.0 0.0 1.8 2 0 0 2 2 2 1 Stage II sporulation protein E (SpoIIE) zf-MYND PF01753.13 KLO10393.1 - 3.2e-11 42.8 7.4 8.9e-11 41.4 5.2 1.8 1 0 0 1 1 1 1 MYND finger SurE PF01975.12 KLO10394.1 - 2.7e-31 108.4 0.2 3.6e-31 108.0 0.1 1.2 1 0 0 1 1 1 1 Survival protein SurE Pkinase PF00069.20 KLO10395.1 - 4.4e-63 212.8 0.0 8.9e-63 211.8 0.0 1.5 1 1 1 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 KLO10395.1 - 9.2e-31 106.8 0.0 1.3e-30 106.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KLO10395.1 - 0.0024 16.9 0.0 0.0037 16.2 0.0 1.3 1 0 0 1 1 1 1 Kinase-like MAT1 PF06391.8 KLO10396.1 - 1.9e-45 154.9 13.5 2.4e-45 154.6 9.3 1.1 1 0 0 1 1 1 1 CDK-activating kinase assembly factor MAT1 zf-RING_5 PF14634.1 KLO10396.1 - 1.1e-05 25.0 7.8 4.1e-05 23.2 5.6 1.8 1 1 1 2 2 2 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 KLO10396.1 - 3.6e-05 23.3 7.7 9.6e-05 21.9 5.3 1.7 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KLO10396.1 - 9.6e-05 21.9 6.1 0.00029 20.4 4.4 1.7 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KLO10396.1 - 0.00022 21.1 7.0 0.00058 19.8 5.0 1.7 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KLO10396.1 - 0.00066 19.4 7.8 0.0014 18.4 5.4 1.5 1 1 0 1 1 1 1 Ring finger domain DUF3887 PF13026.1 KLO10396.1 - 0.0026 18.0 0.4 0.0026 18.0 0.3 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF3887) zf-RING_4 PF14570.1 KLO10396.1 - 0.0065 16.0 3.0 0.21 11.2 0.9 2.3 2 0 0 2 2 2 1 RING/Ubox like zinc-binding domain zf-rbx1 PF12678.2 KLO10396.1 - 0.0081 16.2 1.5 0.015 15.3 1.0 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger DUF3040 PF11239.3 KLO10396.1 - 0.27 11.3 1.8 0.71 9.9 1.0 2.0 2 0 0 2 2 1 0 Protein of unknown function (DUF3040) zf-RING_UBOX PF13445.1 KLO10396.1 - 0.66 9.7 4.4 0.78 9.5 1.1 2.4 1 1 1 2 2 2 0 RING-type zinc-finger SieB PF14163.1 KLO10396.1 - 0.86 9.1 2.5 1.6 8.3 1.7 1.4 1 0 0 1 1 1 0 Superinfection exclusion protein B zf-C3HC4_4 PF15227.1 KLO10396.1 - 2.9 7.8 7.4 40 4.2 5.9 2.3 1 1 1 2 2 2 0 zinc finger of C3HC4-type, RING Strabismus PF06638.6 KLO10396.1 - 5.2 5.2 9.4 6.5 4.9 6.0 1.5 2 0 0 2 2 2 0 Strabismus protein Lactonase PF10282.4 KLO10397.1 - 3.8e-40 138.0 0.0 4.5e-40 137.7 0.0 1.0 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller Misat_Tub_SegII PF10644.4 KLO10397.1 - 0.07 13.1 0.1 0.11 12.5 0.1 1.3 1 0 0 1 1 1 0 Misato Segment II tubulin-like domain LigB PF02900.13 KLO10398.1 - 7.7e-40 136.5 0.0 9.4e-40 136.3 0.0 1.1 1 0 0 1 1 1 1 Catalytic LigB subunit of aromatic ring-opening dioxygenase DUF2172 PF09940.4 KLO10398.1 - 0.068 11.5 0.0 0.1 10.9 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF2172) DUF3415 PF11895.3 KLO10399.1 - 2e-17 62.7 0.4 4e-17 61.8 0.3 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3415) peroxidase PF00141.18 KLO10399.1 - 1e-14 54.5 0.0 1.5e-12 47.5 0.0 2.2 1 1 0 1 1 1 1 Peroxidase peroxidase PF00141.18 KLO10400.1 - 1.2e-23 83.7 0.0 2e-23 83.1 0.0 1.4 1 0 0 1 1 1 1 Peroxidase DUF3415 PF11895.3 KLO10400.1 - 2.5e-23 81.7 2.7 5.1e-23 80.7 1.8 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3415) DUF627 PF04781.7 KLO10400.1 - 0.15 11.6 0.0 0.25 10.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF627) EF-hand_4 PF12763.2 KLO10402.1 - 0.053 13.2 0.0 0.11 12.2 0.0 1.4 1 0 0 1 1 1 0 Cytoskeletal-regulatory complex EF hand APG9 PF04109.11 KLO10403.1 - 2.8e-155 516.8 2.6 3.6e-155 516.4 1.8 1.1 1 0 0 1 1 1 1 Autophagy protein Apg9 NAD_binding_7 PF13241.1 KLO10404.1 - 2.8e-29 101.3 0.0 6.2e-29 100.2 0.0 1.6 2 0 0 2 2 2 1 Putative NAD(P)-binding Sirohm_synth_C PF14823.1 KLO10404.1 - 1e-22 79.1 0.1 1.7e-22 78.4 0.1 1.4 1 0 0 1 1 1 1 Sirohaem biosynthesis protein C-terminal Sirohm_synth_M PF14824.1 KLO10404.1 - 6.1e-14 50.6 0.3 9.6e-14 50.0 0.2 1.3 1 0 0 1 1 1 1 Sirohaem biosynthesis protein central ThiF PF00899.16 KLO10404.1 - 0.082 12.7 1.5 0.13 12.0 0.0 2.0 2 0 0 2 2 2 0 ThiF family DUF2420 PF10336.4 KLO10405.1 - 7.9e-17 60.8 0.1 1.5e-16 59.9 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2420) HTH_9 PF08221.6 KLO10406.1 - 2.7e-20 71.9 1.2 1e-13 50.9 0.9 3.7 4 0 0 4 4 4 2 RNA polymerase III subunit RPC82 helix-turn-helix domain TFIIE_alpha PF02002.12 KLO10406.1 - 1.6e-14 53.2 0.3 5.2e-10 38.7 0.0 4.1 4 0 0 4 4 4 2 TFIIE alpha subunit RNA_pol_Rpc82 PF05645.8 KLO10406.1 - 2.4e-14 53.5 0.4 1.2e-12 47.9 0.4 2.5 2 0 0 2 2 2 1 RNA polymerase III subunit RPC82 PEP-utilisers_N PF05524.8 KLO10406.1 - 0.076 12.8 1.6 0.37 10.6 0.1 2.4 2 0 0 2 2 2 0 PEP-utilising enzyme, N-terminal Metallophos PF00149.23 KLO10407.1 - 1.9e-12 46.9 0.7 4.1e-12 45.9 0.5 1.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 KLO10407.1 - 1.5e-05 24.9 0.0 3.2e-05 23.8 0.0 1.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain MutL PF13941.1 KLO10407.1 - 0.11 10.8 0.0 0.15 10.3 0.0 1.1 1 0 0 1 1 1 0 MutL protein SPT16 PF08644.6 KLO10408.1 - 9.9e-58 194.2 0.2 2.9e-57 192.7 0.1 1.9 1 0 0 1 1 1 1 FACT complex subunit (SPT16/CDC68) FACT-Spt16_Nlob PF14826.1 KLO10408.1 - 1.3e-35 122.3 0.4 4e-35 120.7 0.0 2.1 2 0 0 2 2 2 1 FACT complex subunit SPT16 N-terminal lobe domain Peptidase_M24 PF00557.19 KLO10408.1 - 3.5e-20 72.4 0.0 6.8e-20 71.5 0.0 1.4 1 0 0 1 1 1 1 Metallopeptidase family M24 Rtt106 PF08512.7 KLO10408.1 - 2.9e-19 68.8 0.0 8e-19 67.4 0.0 1.8 1 0 0 1 1 1 1 Histone chaperone Rttp106-like DUF3956 PF13104.1 KLO10408.1 - 0.023 14.2 0.0 0.046 13.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3956) Abhydrolase_6 PF12697.2 KLO10411.1 - 1.9e-32 113.0 0.0 2.2e-32 112.7 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KLO10411.1 - 1.2e-20 74.0 0.0 4.3e-20 72.2 0.0 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KLO10411.1 - 4.2e-15 55.7 0.0 6.1e-15 55.2 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_4 PF08386.5 KLO10411.1 - 0.00012 21.9 0.0 0.00032 20.5 0.0 1.7 1 0 0 1 1 1 1 TAP-like protein Abhydrolase_3 PF07859.8 KLO10411.1 - 0.00015 21.3 0.1 0.0022 17.6 0.0 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold BAAT_C PF08840.6 KLO10411.1 - 0.0022 17.7 0.2 0.47 10.1 0.0 2.1 2 0 0 2 2 2 2 BAAT / Acyl-CoA thioester hydrolase C terminal Hydrolase_4 PF12146.3 KLO10411.1 - 0.0091 15.8 0.0 0.022 14.5 0.0 1.6 2 0 0 2 2 1 1 Putative lysophospholipase Peptidase_S9 PF00326.16 KLO10411.1 - 0.01 15.0 0.1 0.48 9.6 0.0 2.4 2 0 0 2 2 2 0 Prolyl oligopeptidase family DLH PF01738.13 KLO10411.1 - 0.012 14.8 0.0 3.8 6.7 0.0 2.4 2 1 0 2 2 2 0 Dienelactone hydrolase family Thioesterase PF00975.15 KLO10411.1 - 0.031 14.5 0.0 0.085 13.0 0.0 1.7 1 0 0 1 1 1 0 Thioesterase domain UPF0227 PF05728.7 KLO10411.1 - 0.076 12.7 0.0 0.54 9.9 0.0 2.0 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0227) DUF2305 PF10230.4 KLO10411.1 - 0.087 12.2 0.0 0.63 9.4 0.0 2.0 1 1 0 1 1 1 0 Uncharacterised conserved protein (DUF2305) Esterase PF00756.15 KLO10411.1 - 0.12 11.8 0.0 0.21 10.9 0.0 1.6 1 0 0 1 1 1 0 Putative esterase FSH1 PF03959.8 KLO10411.1 - 0.13 11.6 0.0 0.37 10.1 0.0 1.6 1 1 0 1 1 1 0 Serine hydrolase (FSH1) DEAD PF00270.24 KLO10412.1 - 8.7e-20 70.8 0.0 1.8e-19 69.8 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KLO10412.1 - 6.4e-11 41.9 0.2 4.7e-10 39.1 0.0 2.5 3 0 0 3 3 3 1 Helicase conserved C-terminal domain DUF1998 PF09369.5 KLO10412.1 - 8.9e-10 39.0 1.2 2.5e-09 37.5 0.8 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1998) CDT1 PF08839.6 KLO10412.1 - 1.8e-06 27.9 0.0 3.6e-06 27.0 0.0 1.5 1 0 0 1 1 1 1 DNA replication factor CDT1 like FHIPEP PF00771.15 KLO10412.1 - 0.016 13.5 0.3 0.022 13.0 0.2 1.1 1 0 0 1 1 1 0 FHIPEP family Pkinase PF00069.20 KLO10413.1 - 1.1e-23 83.6 0.0 1.7e-23 83.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KLO10413.1 - 5.2e-14 51.9 0.0 1.7e-13 50.2 0.0 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase Cnd1 PF12717.2 KLO10413.1 - 0.094 12.5 0.2 0.2 11.4 0.2 1.5 1 0 0 1 1 1 0 non-SMC mitotic condensation complex subunit 1 PIRT PF15099.1 KLO10415.1 - 0.056 12.6 0.2 0.058 12.6 0.2 1.2 1 0 0 1 1 1 0 Phosphoinositide-interacting protein family HSP20 PF00011.16 KLO10417.1 - 0.00024 20.9 0.0 0.00053 19.7 0.0 1.5 1 1 0 1 1 1 1 Hsp20/alpha crystallin family NAD_binding_11 PF14833.1 KLO10418.1 - 3.4e-32 111.0 0.0 6.2e-32 110.2 0.0 1.4 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase NAD_binding_2 PF03446.10 KLO10418.1 - 1.2e-31 109.7 0.0 1.7e-31 109.2 0.0 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase Epimerase PF01370.16 KLO10419.1 - 2.3e-05 23.9 0.0 3.8e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Syntaxin-18_N PF10496.4 KLO10419.1 - 0.029 14.2 0.0 0.057 13.2 0.0 1.4 1 0 0 1 1 1 0 SNARE-complex protein Syntaxin-18 N-terminus SNAPc19 PF15497.1 KLO10419.1 - 0.086 13.0 0.0 0.18 12.0 0.0 1.5 1 0 0 1 1 1 0 snRNA-activating protein complex subunit 19, SNAPc subunit 19 Cytochrom_B561 PF03188.11 KLO10420.1 - 1.6e-08 34.4 9.9 1.7e-08 34.3 5.5 2.0 1 1 1 2 2 2 1 Eukaryotic cytochrome b561 Sec7 PF01369.15 KLO10421.1 - 4.9e-62 208.9 0.0 9.6e-62 208.0 0.0 1.5 1 0 0 1 1 1 1 Sec7 domain Sec7_N PF12783.2 KLO10421.1 - 5.3e-22 78.0 7.3 7.3e-13 48.2 0.1 4.4 5 0 0 5 5 5 2 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF1981 PF09324.5 KLO10421.1 - 0.00086 18.7 1.2 0.38 10.3 0.0 3.7 3 0 0 3 3 3 1 Domain of unknown function (DUF1981) 5-nucleotidase PF06189.7 KLO10421.1 - 0.065 12.0 0.1 0.19 10.5 0.0 1.7 2 0 0 2 2 2 0 5'-nucleotidase Proteasome PF00227.21 KLO10422.1 - 1.2e-59 200.7 0.0 1.7e-59 200.3 0.0 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 KLO10422.1 - 1.4e-15 56.3 0.2 3.1e-15 55.1 0.0 1.7 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature Peptidase_C78 PF07910.8 KLO10423.1 - 2.9e-43 147.5 0.0 9.7e-43 145.8 0.0 1.8 2 0 0 2 2 2 1 Peptidase family C78 zf-U1 PF06220.7 KLO10423.1 - 0.12 11.9 0.1 0.26 10.8 0.0 1.5 1 0 0 1 1 1 0 U1 zinc finger GreA_GreB PF01272.14 KLO10423.1 - 0.16 11.6 2.1 0.79 9.4 0.7 2.4 2 0 0 2 2 2 0 Transcription elongation factor, GreA/GreB, C-term Aminotran_1_2 PF00155.16 KLO10424.1 - 1.7e-16 60.1 0.0 2.4e-16 59.6 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Pkinase PF00069.20 KLO10425.1 - 9.4e-53 179.0 0.0 1.5e-52 178.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KLO10425.1 - 1.9e-45 154.9 0.0 2.7e-45 154.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase SAP PF02037.22 KLO10425.1 - 0.0065 15.9 0.4 0.02 14.3 0.2 1.9 1 0 0 1 1 1 1 SAP domain APH PF01636.18 KLO10425.1 - 0.0085 15.8 0.0 0.017 14.8 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 KLO10425.1 - 0.089 11.6 0.0 0.14 10.9 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 AAA PF00004.24 KLO10427.1 - 1e-11 45.1 0.0 2.2e-11 44.0 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.10 KLO10427.1 - 2.2e-07 29.9 0.0 0.00019 20.2 0.0 3.0 2 1 0 2 2 2 2 Rad17 cell cycle checkpoint protein AAA_14 PF13173.1 KLO10427.1 - 0.00011 22.1 0.0 0.00021 21.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 KLO10427.1 - 0.001 19.1 0.0 0.037 14.0 0.0 2.8 1 1 1 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 KLO10427.1 - 0.0017 18.5 0.1 0.03 14.4 0.0 2.7 2 1 1 3 3 3 1 AAA domain AAA_19 PF13245.1 KLO10427.1 - 0.0019 17.9 0.1 0.0068 16.1 0.0 1.9 2 0 0 2 2 2 1 Part of AAA domain AAA_17 PF13207.1 KLO10427.1 - 0.0035 18.1 0.0 0.012 16.3 0.0 1.9 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.7 KLO10427.1 - 0.0049 15.9 0.0 0.015 14.3 0.0 1.7 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus MFS_1 PF07690.11 KLO10428.1 - 6e-23 81.1 34.4 9.3e-23 80.4 23.3 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily XH PF03469.9 KLO10428.1 - 0.037 13.6 0.0 0.07 12.7 0.0 1.5 1 0 0 1 1 1 0 XH domain DUF2762 PF10960.3 KLO10428.1 - 0.13 11.9 0.4 2.1 8.1 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2762) Clp1 PF06807.9 KLO10429.1 - 3e-19 69.5 0.0 1.3e-10 41.3 0.0 2.1 2 0 0 2 2 2 2 Pre-mRNA cleavage complex II protein Clp1 MobB PF03205.9 KLO10429.1 - 2.4e-08 33.8 0.0 3.3e-07 30.1 0.0 2.2 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B ATP_bind_1 PF03029.12 KLO10429.1 - 0.046 13.2 0.0 0.086 12.3 0.0 1.4 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein PduV-EutP PF10662.4 KLO10429.1 - 0.11 12.0 0.0 0.94 8.9 0.0 2.1 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Arf PF00025.16 KLO10429.1 - 0.18 11.0 0.0 0.34 10.1 0.0 1.3 1 0 0 1 1 1 0 ADP-ribosylation factor family Pyr_redox_2 PF07992.9 KLO10430.1 - 3.9e-20 72.5 0.1 6.5e-20 71.8 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 KLO10430.1 - 1.1e-12 48.1 0.2 6.1e-09 36.1 0.0 3.5 4 0 0 4 4 4 2 Pyridine nucleotide-disulphide oxidoreductase EF-hand_7 PF13499.1 KLO10430.1 - 2.6e-10 40.2 6.3 6.8e-08 32.5 0.8 2.0 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.27 KLO10430.1 - 2.8e-10 38.7 0.6 0.0002 20.4 0.0 2.5 2 0 0 2 2 2 2 EF hand Pyr_redox_3 PF13738.1 KLO10430.1 - 7.9e-07 29.3 0.0 0.49 10.4 0.0 3.3 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase EF-hand_6 PF13405.1 KLO10430.1 - 9.3e-07 28.2 0.9 0.0056 16.4 0.2 2.5 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.1 KLO10430.1 - 1e-06 27.7 2.6 0.00035 19.7 0.1 2.5 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.1 KLO10430.1 - 1.4e-05 24.6 0.1 0.18 11.4 0.0 2.5 2 0 0 2 2 2 2 EF-hand domain pair NAD_binding_7 PF13241.1 KLO10430.1 - 0.018 15.2 0.1 0.11 12.7 0.0 2.4 2 1 0 2 2 2 0 Putative NAD(P)-binding Glyco_tranf_2_5 PF13712.1 KLO10430.1 - 0.022 14.0 0.4 0.038 13.2 0.2 1.3 1 0 0 1 1 1 0 Glycosyltransferase like family SPARC_Ca_bdg PF10591.4 KLO10430.1 - 0.066 13.2 0.3 7.2 6.6 0.0 2.4 2 0 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region NAD_binding_9 PF13454.1 KLO10430.1 - 0.082 12.6 0.0 4.4 7.0 0.0 2.9 3 0 0 3 3 3 0 FAD-NAD(P)-binding EF-hand_4 PF12763.2 KLO10430.1 - 0.39 10.4 1.9 17 5.1 0.1 2.5 1 1 1 2 2 2 0 Cytoskeletal-regulatory complex EF hand ATP-synt_ab PF00006.20 KLO10431.1 - 6.2e-63 212.1 0.0 1.1e-62 211.4 0.0 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 KLO10431.1 - 3.7e-24 85.3 0.7 6.3e-24 84.6 0.5 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 KLO10431.1 - 3.1e-22 78.5 1.3 8.4e-22 77.1 0.9 1.8 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain NB-ARC PF00931.17 KLO10431.1 - 0.01 14.7 0.8 0.029 13.2 0.1 1.9 2 0 0 2 2 2 1 NB-ARC domain AAA PF00004.24 KLO10431.1 - 0.016 15.4 0.0 0.31 11.2 0.0 2.5 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) NACHT PF05729.7 KLO10431.1 - 0.023 14.3 0.0 0.053 13.1 0.0 1.7 1 0 0 1 1 1 0 NACHT domain Arch_ATPase PF01637.13 KLO10431.1 - 0.023 14.3 0.0 0.051 13.2 0.0 1.5 1 0 0 1 1 1 0 Archaeal ATPase AAA_25 PF13481.1 KLO10431.1 - 0.024 14.0 0.1 0.055 12.8 0.0 1.6 1 1 0 1 1 1 0 AAA domain MobB PF03205.9 KLO10431.1 - 0.03 14.0 0.2 2 8.1 0.0 2.9 3 0 0 3 3 3 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_22 PF13401.1 KLO10431.1 - 0.041 14.0 0.0 0.11 12.6 0.0 1.7 1 1 0 1 1 1 0 AAA domain DUF258 PF03193.11 KLO10431.1 - 0.043 12.9 0.1 0.077 12.1 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 KaiC PF06745.8 KLO10431.1 - 0.045 12.8 0.1 0.08 12.0 0.1 1.4 1 0 0 1 1 1 0 KaiC AAA_16 PF13191.1 KLO10431.1 - 0.049 13.6 0.1 0.14 12.0 0.0 1.8 1 1 0 1 1 1 0 AAA ATPase domain CPDase PF07823.6 KLO10432.1 - 1.7e-21 76.6 0.0 3.3e-21 75.6 0.0 1.5 1 1 0 1 1 1 1 Cyclic phosphodiesterase-like protein 2_5_RNA_ligase2 PF13563.1 KLO10432.1 - 9.2e-05 22.2 0.1 0.00012 21.7 0.1 1.4 1 1 0 1 1 1 1 2'-5' RNA ligase superfamily LigT_PEase PF02834.11 KLO10432.1 - 0.0012 18.7 0.1 0.0062 16.4 0.0 1.9 2 0 0 2 2 2 1 LigT like Phosphoesterase CPDase PF07823.6 KLO10433.1 - 0.00019 20.9 0.0 0.00028 20.4 0.0 1.2 1 0 0 1 1 1 1 Cyclic phosphodiesterase-like protein Topo_C_assoc PF14370.1 KLO10433.1 - 0.11 12.1 0.2 1.2 8.8 0.0 2.4 3 0 0 3 3 3 0 C-terminal topoisomerase domain Histone PF00125.19 KLO10434.1 - 4.1e-30 103.7 0.8 6.6e-30 103.0 0.6 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 KLO10434.1 - 1.4e-05 25.2 0.1 2.2e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 Kinetochore component CENP-S CBFD_NFYB_HMF PF00808.18 KLO10434.1 - 0.00053 20.0 0.6 0.0013 18.7 0.1 1.8 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Bromo_TP PF07524.8 KLO10434.1 - 0.015 15.0 0.1 0.026 14.2 0.1 1.4 1 0 0 1 1 1 0 Bromodomain associated CENP-T PF15511.1 KLO10434.1 - 0.21 10.8 2.3 0.26 10.4 1.6 1.4 1 1 0 1 1 1 0 Centromere kinetochore component CENP-T Pkinase PF00069.20 KLO10435.1 - 3.3e-74 249.3 0.0 4.5e-74 248.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KLO10435.1 - 1e-39 136.1 0.0 1.5e-39 135.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KLO10435.1 - 3.6e-06 26.1 0.0 5.5e-06 25.5 0.0 1.3 1 0 0 1 1 1 1 Kinase-like UBA_2 PF08587.6 KLO10435.1 - 2.1e-05 24.5 0.0 5.7e-05 23.2 0.0 1.8 1 0 0 1 1 1 1 Ubiquitin associated domain (UBA) RIO1 PF01163.17 KLO10435.1 - 0.00013 21.4 0.1 0.00022 20.6 0.0 1.3 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.9 KLO10435.1 - 0.03 13.3 0.2 0.11 11.5 0.1 2.0 2 1 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KLO10435.1 - 0.066 12.9 1.8 0.13 11.9 0.1 2.2 2 1 1 3 3 3 0 Phosphotransferase enzyme family YukC PF10140.4 KLO10435.1 - 0.12 10.9 0.0 0.19 10.2 0.0 1.3 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukC An_peroxidase PF03098.10 KLO10438.1 - 4.2e-75 253.1 0.0 1.1e-72 245.1 0.0 2.1 1 1 0 1 1 1 1 Animal haem peroxidase p450 PF00067.17 KLO10438.1 - 0.00029 19.4 0.0 0.0043 15.6 0.0 2.5 1 1 1 2 2 2 1 Cytochrome P450 Acetyltransf_1 PF00583.19 KLO10444.1 - 3.6e-10 39.7 0.0 6.4e-10 38.9 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 KLO10444.1 - 3.6e-08 33.5 0.0 6.4e-08 32.7 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 KLO10444.1 - 1.3e-07 31.2 0.0 2.5e-07 30.3 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.1 KLO10444.1 - 6.5e-07 29.2 0.0 1.5e-06 28.0 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 KLO10444.1 - 8.9e-06 25.9 0.0 2.2e-05 24.6 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 KLO10444.1 - 7.4e-05 22.8 0.0 0.00014 21.9 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 KLO10444.1 - 0.0004 20.2 0.0 0.00081 19.2 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 KLO10444.1 - 0.001 18.8 0.1 0.002 18.0 0.0 1.4 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Asp PF00026.18 KLO10446.1 - 1e-46 159.6 10.3 1.3e-46 159.2 7.2 1.2 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 KLO10446.1 - 2.8e-05 24.1 2.5 0.00032 20.6 0.8 2.8 1 1 1 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 KLO10446.1 - 0.00024 21.5 4.2 0.021 15.3 0.3 2.7 2 0 0 2 2 2 2 Aspartyl protease DUF3980 PF13140.1 KLO10452.1 - 0.088 13.0 4.4 0.41 10.9 3.0 2.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3980) Asp PF00026.18 KLO10453.1 - 1.3e-50 172.4 6.7 2.5e-50 171.5 4.6 1.4 1 1 0 1 1 1 1 Eukaryotic aspartyl protease Asp_protease_2 PF13650.1 KLO10453.1 - 3.5e-08 33.8 2.8 0.00023 21.6 0.2 2.6 2 0 0 2 2 2 2 Aspartyl protease TAXi_N PF14543.1 KLO10453.1 - 2.3e-06 27.6 1.5 2.5e-05 24.3 0.4 2.8 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal gag-asp_proteas PF13975.1 KLO10453.1 - 0.015 15.0 0.1 1 9.1 0.0 2.5 2 0 0 2 2 2 0 gag-polyprotein putative aspartyl protease TAXi_C PF14541.1 KLO10453.1 - 0.085 12.4 0.0 0.33 10.4 0.0 2.0 1 1 0 1 1 1 0 Xylanase inhibitor C-terminal Arrestin_C PF02752.17 KLO10454.1 - 1.9e-07 31.2 0.0 5.8e-07 29.6 0.0 1.8 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain DUF1793 PF08760.6 KLO10456.1 - 8e-33 113.6 0.0 1.5e-32 112.8 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1793) DUF3981 PF13139.1 KLO10457.1 - 0.061 13.3 0.1 0.061 13.3 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3981) DUF1793 PF08760.6 KLO10459.1 - 6.6e-38 130.2 0.0 1.1e-37 129.5 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1793) Bac_rhamnosid PF05592.6 KLO10459.1 - 0.029 12.6 0.0 0.079 11.1 0.0 1.5 1 1 0 1 1 1 0 Bacterial alpha-L-rhamnosidase DUF1793 PF08760.6 KLO10460.1 - 6.6e-36 123.7 0.0 1.1e-35 123.0 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1793) Bac_rhamnosid PF05592.6 KLO10460.1 - 0.044 12.0 0.2 0.1 10.7 0.1 1.4 1 1 0 1 1 1 0 Bacterial alpha-L-rhamnosidase AAA_16 PF13191.1 KLO10462.1 - 4.9e-07 29.9 0.0 1.8e-06 28.0 0.0 2.0 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 KLO10462.1 - 6.2e-07 29.6 0.0 4e-06 26.9 0.0 2.2 2 0 0 2 2 2 1 AAA domain NACHT PF05729.7 KLO10462.1 - 2.8e-06 27.0 0.0 5e-06 26.2 0.0 1.4 1 0 0 1 1 1 1 NACHT domain AAA_25 PF13481.1 KLO10462.1 - 0.0054 16.1 0.0 0.015 14.6 0.0 1.7 1 1 0 1 1 1 1 AAA domain PPV_E1_C PF00519.12 KLO10462.1 - 0.0085 14.7 0.0 0.016 13.8 0.0 1.3 1 0 0 1 1 1 1 Papillomavirus helicase RNA_helicase PF00910.17 KLO10462.1 - 0.016 15.3 0.0 0.036 14.2 0.0 1.6 1 0 0 1 1 1 0 RNA helicase HCaRG PF07258.9 KLO10462.1 - 0.019 14.5 0.2 0.042 13.4 0.2 1.5 1 0 0 1 1 1 0 HCaRG protein AAA_17 PF13207.1 KLO10462.1 - 0.038 14.8 0.0 0.18 12.6 0.0 2.3 1 0 0 1 1 1 0 AAA domain Arch_ATPase PF01637.13 KLO10462.1 - 0.047 13.3 0.0 0.21 11.2 0.0 2.0 2 0 0 2 2 2 0 Archaeal ATPase AAA PF00004.24 KLO10462.1 - 0.1 12.7 0.0 0.73 10.0 0.0 2.4 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.1 KLO10462.1 - 0.11 12.4 0.0 0.55 10.1 0.0 2.2 3 0 0 3 3 3 0 AAA domain CPT PF07931.7 KLO10462.1 - 0.12 11.9 0.0 2.4 7.7 0.0 2.3 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein KaiC PF06745.8 KLO10462.1 - 0.15 11.2 0.0 0.34 9.9 0.0 1.5 1 0 0 1 1 1 0 KaiC DUF4150 PF13665.1 KLO10464.1 - 0.061 13.2 0.0 0.1 12.4 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4150) AAA_16 PF13191.1 KLO10466.1 - 0.00076 19.5 0.0 0.0025 17.8 0.0 1.8 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 KLO10466.1 - 0.0023 18.0 0.0 0.0056 16.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain NACHT PF05729.7 KLO10466.1 - 0.014 15.0 0.0 0.027 14.1 0.0 1.6 1 0 0 1 1 1 0 NACHT domain NB-ARC PF00931.17 KLO10466.1 - 0.11 11.3 0.0 0.17 10.7 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain Alpha-2-MRAP_N PF06400.6 KLO10466.1 - 0.18 11.5 0.1 0.41 10.3 0.0 1.6 2 0 0 2 2 2 0 Alpha-2-macroglobulin RAP, N-terminal domain NACHT PF05729.7 KLO10467.1 - 5.6e-06 26.1 0.0 1e-05 25.2 0.0 1.4 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 KLO10467.1 - 3.6e-05 23.8 0.0 0.00016 21.7 0.0 2.1 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 KLO10467.1 - 0.0004 20.5 0.0 0.0018 18.4 0.0 2.0 1 1 1 2 2 2 1 AAA domain INT_SG_DDX_CT_C PF15300.1 KLO10467.1 - 0.11 12.0 0.2 4.6 6.7 0.0 2.5 2 0 0 2 2 2 0 INTS6/SAGE1/DDX26B/CT45 C-terminus PPV_E1_C PF00519.12 KLO10467.1 - 0.12 11.0 0.0 0.18 10.3 0.0 1.2 1 0 0 1 1 1 0 Papillomavirus helicase KAP_NTPase PF07693.9 KLO10467.1 - 0.16 10.9 1.3 4.4 6.1 0.2 2.3 2 0 0 2 2 2 0 KAP family P-loop domain AAA_17 PF13207.1 KLO10467.1 - 0.25 12.1 1.5 2 9.2 0.4 2.8 2 1 0 2 2 2 0 AAA domain zf-RVT PF13966.1 KLO10469.1 - 0.0029 17.8 0.1 0.0073 16.6 0.1 1.8 1 1 1 2 2 2 1 zinc-binding in reverse transcriptase RNase_H PF00075.19 KLO10469.1 - 0.0099 16.2 0.1 0.033 14.5 0.0 1.8 2 0 0 2 2 2 1 RNase H NACHT PF05729.7 KLO10470.1 - 4.2e-10 39.5 0.0 1.5e-06 27.9 0.0 3.0 2 0 0 2 2 2 2 NACHT domain AAA_22 PF13401.1 KLO10470.1 - 3.1e-09 37.0 0.0 6.3e-07 29.5 0.0 3.2 3 0 0 3 3 3 1 AAA domain AAA_16 PF13191.1 KLO10470.1 - 3.4e-08 33.6 0.0 0.0014 18.6 0.0 3.4 3 1 0 3 3 3 2 AAA ATPase domain AAA PF00004.24 KLO10470.1 - 0.0015 18.7 0.1 0.24 11.6 0.0 4.0 4 2 0 4 4 4 1 ATPase family associated with various cellular activities (AAA) APS_kinase PF01583.15 KLO10470.1 - 0.013 15.1 1.5 0.68 9.5 0.0 2.7 3 0 0 3 3 3 0 Adenylylsulphate kinase DUF1765 PF08578.5 KLO10470.1 - 0.015 15.3 0.1 3.7 7.6 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1765) AAA_14 PF13173.1 KLO10470.1 - 0.025 14.4 0.0 12 5.7 0.0 3.3 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.1 KLO10470.1 - 0.1 13.4 1.8 3.8 8.3 0.0 3.9 2 2 0 2 2 2 0 AAA domain NACHT PF05729.7 KLO10473.1 - 9.3e-14 51.4 0.4 8.9e-06 25.4 0.0 3.0 3 0 0 3 3 3 2 NACHT domain AAA_16 PF13191.1 KLO10473.1 - 6e-12 45.9 0.3 0.00029 20.9 0.0 3.7 2 2 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.1 KLO10473.1 - 1.1e-09 38.5 0.0 3.6e-05 23.9 0.0 3.4 4 0 0 4 4 4 2 AAA domain KAP_NTPase PF07693.9 KLO10473.1 - 3.9e-07 29.3 0.8 0.0011 18.0 0.0 3.4 3 0 0 3 3 3 1 KAP family P-loop domain NB-ARC PF00931.17 KLO10473.1 - 0.00021 20.2 0.0 0.31 9.8 0.0 2.6 2 0 0 2 2 2 2 NB-ARC domain AAA PF00004.24 KLO10473.1 - 0.00029 21.0 0.0 0.18 11.9 0.0 3.5 3 2 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.17 KLO10473.1 - 0.0029 17.7 0.0 1 9.5 0.0 2.8 2 0 0 2 2 2 1 RNA helicase AAA_18 PF13238.1 KLO10473.1 - 0.032 14.5 0.0 0.86 9.9 0.0 3.3 3 1 0 3 3 3 0 AAA domain AAA_25 PF13481.1 KLO10473.1 - 0.047 13.0 0.0 0.37 10.1 0.0 2.4 2 0 0 2 2 2 0 AAA domain APS_kinase PF01583.15 KLO10473.1 - 0.078 12.6 0.7 16 5.1 0.0 3.0 3 0 0 3 3 3 0 Adenylylsulphate kinase AAA_19 PF13245.1 KLO10473.1 - 0.13 11.9 0.0 11 5.8 0.0 2.8 2 0 0 2 2 2 0 Part of AAA domain AAA_17 PF13207.1 KLO10473.1 - 0.2 12.4 1.8 4.6 8.0 0.0 3.8 4 1 0 4 4 4 0 AAA domain AAA_16 PF13191.1 KLO10476.1 - 2.2e-08 34.3 0.0 2.9e-08 33.9 0.0 1.3 1 1 0 1 1 1 1 AAA ATPase domain NACHT PF05729.7 KLO10476.1 - 1.8e-07 30.9 0.0 2.3e-07 30.5 0.0 1.2 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.1 KLO10476.1 - 7.3e-06 26.1 0.0 1.1e-05 25.5 0.0 1.4 1 1 0 1 1 1 1 AAA domain Arch_ATPase PF01637.13 KLO10476.1 - 6.1e-05 22.8 0.0 7e-05 22.6 0.0 1.1 1 0 0 1 1 1 1 Archaeal ATPase AAA_33 PF13671.1 KLO10476.1 - 0.0042 16.9 0.0 0.0067 16.3 0.0 1.3 1 1 0 1 1 1 1 AAA domain RNA_helicase PF00910.17 KLO10476.1 - 0.027 14.6 0.0 0.04 14.0 0.0 1.4 1 0 0 1 1 1 0 RNA helicase DUF2075 PF09848.4 KLO10476.1 - 0.034 13.1 0.0 0.034 13.1 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) NB-ARC PF00931.17 KLO10476.1 - 0.041 12.7 0.0 0.043 12.6 0.0 1.1 1 0 0 1 1 1 0 NB-ARC domain NTPase_1 PF03266.10 KLO10476.1 - 0.055 13.1 0.0 0.082 12.6 0.0 1.3 1 0 0 1 1 1 0 NTPase AAA_16 PF13191.1 KLO10479.1 - 5.1e-06 26.5 0.1 1.6e-05 24.9 0.0 1.8 1 1 0 1 1 1 1 AAA ATPase domain NACHT PF05729.7 KLO10479.1 - 9.8e-06 25.3 0.0 2.4e-05 24.0 0.0 1.7 1 1 0 1 1 1 1 NACHT domain AAA_22 PF13401.1 KLO10479.1 - 3.5e-05 23.9 0.0 0.00031 20.9 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA PF00004.24 KLO10479.1 - 0.0024 18.0 0.0 0.0086 16.2 0.0 1.9 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) NB-ARC PF00931.17 KLO10479.1 - 0.0062 15.4 0.0 0.01 14.7 0.0 1.4 1 0 0 1 1 1 1 NB-ARC domain KAP_NTPase PF07693.9 KLO10479.1 - 0.11 11.5 1.2 0.18 10.7 0.2 1.6 1 1 0 2 2 2 0 KAP family P-loop domain AAA_19 PF13245.1 KLO10479.1 - 0.12 12.1 0.0 0.27 11.0 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain AAA_18 PF13238.1 KLO10479.1 - 0.13 12.5 0.1 1.2 9.4 0.0 2.5 2 1 0 2 2 2 0 AAA domain DUF2376 PF09550.5 KLO10479.1 - 0.87 9.7 2.8 1.7 8.8 0.2 2.5 2 1 0 2 2 2 0 Conserved hypothetical phage protein (DUF2376) AAA_16 PF13191.1 KLO10480.1 - 1.2e-06 28.6 0.0 1.9e-06 28.0 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain NACHT PF05729.7 KLO10480.1 - 4.1e-06 26.5 0.0 7.4e-06 25.7 0.0 1.4 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.1 KLO10480.1 - 4.3e-05 23.6 0.0 7.7e-05 22.8 0.0 1.4 1 1 0 1 1 1 1 AAA domain Arch_ATPase PF01637.13 KLO10480.1 - 4.3e-05 23.3 0.0 5.3e-05 23.0 0.0 1.1 1 0 0 1 1 1 1 Archaeal ATPase NB-ARC PF00931.17 KLO10480.1 - 0.059 12.2 0.0 0.065 12.0 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain RNA_helicase PF00910.17 KLO10480.1 - 0.11 12.6 0.0 0.2 11.8 0.0 1.4 1 0 0 1 1 1 0 RNA helicase AAA_25 PF13481.1 KLO10480.1 - 0.13 11.6 0.0 0.19 11.1 0.0 1.4 1 1 0 1 1 1 0 AAA domain ArgK PF03308.11 KLO10480.1 - 0.13 10.9 0.0 0.19 10.4 0.0 1.2 1 0 0 1 1 1 0 ArgK protein DnaB_C PF03796.10 KLO10480.1 - 0.14 11.0 0.0 0.16 10.8 0.0 1.1 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain AAA_18 PF13238.1 KLO10480.1 - 0.2 11.9 1.8 2.4 8.4 0.1 2.4 1 1 0 2 2 2 0 AAA domain DUF3074 PF11274.3 KLO10482.1 - 0.076 12.6 0.0 0.087 12.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3074) F-box-like PF12937.2 KLO10485.1 - 0.0011 18.6 0.6 0.0078 15.9 0.4 2.5 1 1 0 1 1 1 1 F-box-like CAP PF00188.21 KLO10487.1 - 3.1e-22 79.3 6.5 3.8e-22 79.0 4.5 1.1 1 0 0 1 1 1 1 Cysteine-rich secretory protein family MFS_1 PF07690.11 KLO10488.1 - 7.6e-28 97.2 45.9 9.2e-25 87.0 24.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Folate_carrier PF01770.13 KLO10488.1 - 0.00017 20.2 6.0 0.00019 20.1 3.4 1.6 2 0 0 2 2 2 1 Reduced folate carrier DUF1228 PF06779.9 KLO10488.1 - 0.0029 17.5 0.6 0.0029 17.5 0.4 2.7 3 0 0 3 3 3 1 Protein of unknown function (DUF1228) DUF3357 PF11837.3 KLO10488.1 - 0.14 12.0 1.0 1e+02 2.8 0.1 3.6 3 0 0 3 3 3 0 Domain of unknown function (DUF3357) SPC12 PF06645.8 KLO10488.1 - 9.7 6.0 11.0 9.8 6.0 0.5 4.0 2 1 1 3 3 3 0 Microsomal signal peptidase 12 kDa subunit (SPC12) F-box-like PF12937.2 KLO10489.1 - 1e-07 31.5 0.4 1.1e-06 28.3 0.0 2.6 2 0 0 2 2 2 1 F-box-like TPR_11 PF13414.1 KLO10490.1 - 6.7e-13 48.0 0.1 3.6e-07 29.7 0.0 2.5 1 1 1 2 2 2 2 TPR repeat F-box-like PF12937.2 KLO10490.1 - 9.2e-09 34.9 0.9 1.7e-08 34.0 0.1 1.9 2 0 0 2 2 2 1 F-box-like TPR_1 PF00515.23 KLO10490.1 - 9.3e-08 31.3 0.0 0.0066 16.0 0.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.12 KLO10490.1 - 2.8e-07 29.9 0.0 0.28 11.2 0.0 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.1 KLO10490.1 - 6.6e-05 23.2 0.0 0.49 11.1 0.0 3.6 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.1 KLO10490.1 - 0.0004 20.9 0.0 0.081 13.6 0.0 2.5 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_19 PF14559.1 KLO10490.1 - 0.00056 20.2 0.1 0.24 11.7 0.0 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat ChAPs PF09295.5 KLO10490.1 - 0.0023 16.7 0.1 0.0044 15.8 0.0 1.4 2 0 0 2 2 2 1 ChAPs (Chs5p-Arf1p-binding proteins) LRR_6 PF13516.1 KLO10490.1 - 0.0043 16.9 0.1 17 5.9 0.0 4.5 4 0 0 4 4 4 0 Leucine Rich repeat TPR_9 PF13371.1 KLO10490.1 - 0.012 15.4 0.0 0.057 13.2 0.0 2.0 1 1 1 2 2 2 0 Tetratricopeptide repeat LRR_7 PF13504.1 KLO10490.1 - 0.022 14.9 1.5 56 4.5 0.0 5.8 6 1 0 6 6 5 0 Leucine rich repeat F-box PF00646.28 KLO10490.1 - 0.085 12.5 0.7 0.58 9.8 0.5 2.5 1 1 0 1 1 1 0 F-box domain TPR_12 PF13424.1 KLO10490.1 - 0.13 12.1 0.0 1.4 8.9 0.0 2.5 1 1 1 2 2 2 0 Tetratricopeptide repeat LRR_4 PF12799.2 KLO10490.1 - 0.14 11.7 4.2 1.3 8.7 0.0 4.2 4 1 0 4 4 4 0 Leucine Rich repeats (2 copies) FMN_dh PF01070.13 KLO10491.1 - 1.4e-111 372.8 0.0 1.8e-111 372.4 0.0 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.23 KLO10491.1 - 2.8e-23 81.5 0.0 4.7e-23 80.7 0.0 1.4 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Glu_synthase PF01645.12 KLO10491.1 - 0.0001 21.3 0.0 0.00018 20.5 0.0 1.4 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.20 KLO10491.1 - 0.00012 21.1 0.4 0.00041 19.3 0.2 1.8 1 1 1 2 2 2 1 IMP dehydrogenase / GMP reductase domain NMO PF03060.10 KLO10491.1 - 0.00025 20.3 0.0 0.00039 19.6 0.0 1.3 1 0 0 1 1 1 1 Nitronate monooxygenase DDE_1 PF03184.14 KLO10496.1 - 5.4e-48 163.0 0.1 7.7e-48 162.4 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.11 KLO10496.1 - 5.7e-10 38.8 0.2 1.4e-09 37.6 0.1 1.7 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain DDE_3 PF13358.1 KLO10496.1 - 0.056 13.1 0.0 0.14 11.8 0.0 1.7 1 0 0 1 1 1 0 DDE superfamily endonuclease zf-TRAF PF02176.13 KLO10498.1 - 0.12 12.7 0.1 0.56 10.6 0.0 2.0 2 0 0 2 2 2 0 TRAF-type zinc finger DUF4266 PF14086.1 KLO10509.1 - 3.2 8.3 9.4 0.72 10.4 0.2 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4266) MutH PF02976.10 KLO10511.1 - 0.11 12.4 0.0 0.17 11.7 0.0 1.2 1 0 0 1 1 1 0 DNA mismatch repair enzyme MutH PLATZ PF04640.9 KLO10515.1 - 0.11 12.6 0.0 0.21 11.8 0.0 1.6 1 0 0 1 1 1 0 PLATZ transcription factor DUF1088 PF06469.6 KLO10520.1 - 0.0031 16.9 0.5 0.49 9.7 0.1 2.3 2 0 0 2 2 2 2 Domain of Unknown Function (DUF1088) Mu-like_Com PF10122.4 KLO10520.1 - 0.097 11.7 0.2 0.25 10.4 0.1 1.7 1 0 0 1 1 1 0 Mu-like prophage protein Com DEAD PF00270.24 KLO10525.1 - 1.4e-10 40.9 0.0 2.9e-08 33.4 0.0 2.5 2 1 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KLO10525.1 - 0.021 14.6 0.0 0.068 13.0 0.0 1.9 1 0 0 1 1 1 0 Helicase conserved C-terminal domain DUF3140 PF11338.3 KLO10526.1 - 0.031 14.3 0.1 24 5.1 0.0 3.6 3 1 0 3 3 3 0 Protein of unknown function (DUF3140) CPDase PF07823.6 KLO10528.1 - 2.8e-15 56.3 0.0 4e-15 55.8 0.0 1.2 1 0 0 1 1 1 1 Cyclic phosphodiesterase-like protein 2_5_RNA_ligase2 PF13563.1 KLO10528.1 - 0.0033 17.1 0.0 0.0046 16.6 0.0 1.3 1 0 0 1 1 1 1 2'-5' RNA ligase superfamily LigT_PEase PF02834.11 KLO10528.1 - 0.06 13.3 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 LigT like Phosphoesterase MFS_1 PF07690.11 KLO10530.1 - 2.9e-21 75.5 27.5 4.1e-20 71.7 18.1 2.4 1 1 0 1 1 1 1 Major Facilitator Superfamily DUF1212 PF06738.7 KLO10530.1 - 5.1 6.5 15.0 0.45 9.9 2.5 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1212) Brix PF04427.13 KLO10531.1 - 1.6e-29 102.9 0.0 2.1e-29 102.5 0.0 1.1 1 0 0 1 1 1 1 Brix domain DUF1776 PF08643.5 KLO10533.1 - 1.4e-09 37.5 0.0 2e-09 37.0 0.0 1.3 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) KH_1 PF00013.24 KLO10534.1 - 7.7e-39 131.1 8.1 5.1e-15 54.8 0.2 3.2 3 0 0 3 3 3 3 KH domain KH_3 PF13014.1 KLO10534.1 - 1.6e-31 107.4 13.9 3.3e-11 42.5 1.0 3.6 3 0 0 3 3 3 3 KH domain KH_2 PF07650.12 KLO10534.1 - 3.3e-14 52.2 6.6 1.3e-05 24.6 0.1 3.3 3 0 0 3 3 3 3 KH domain KH_4 PF13083.1 KLO10534.1 - 6.9e-05 22.4 2.4 0.23 11.1 0.0 3.3 3 0 0 3 3 3 2 KH domain KH_5 PF13184.1 KLO10534.1 - 0.024 14.4 6.0 7.6 6.4 0.1 3.4 3 0 0 3 3 3 0 NusA-like KH domain CRF PF00473.12 KLO10534.1 - 0.03 14.3 0.8 0.062 13.4 0.5 1.5 1 0 0 1 1 1 0 Corticotropin-releasing factor family A_deaminase PF00962.17 KLO10535.1 - 1.2e-45 155.9 0.0 8.2e-45 153.1 0.0 1.9 1 1 0 1 1 1 1 Adenosine/AMP deaminase A_deaminase_N PF08451.6 KLO10535.1 - 6.8e-06 26.0 0.0 3.7e-05 23.6 0.0 2.1 2 0 0 2 2 2 1 Adenosine/AMP deaminase N-terminal PriCT_2 PF08707.6 KLO10535.1 - 0.068 13.0 0.2 0.16 11.8 0.2 1.6 1 0 0 1 1 1 0 Primase C terminal 2 (PriCT-2) NmrA PF05368.8 KLO10536.1 - 5.4e-42 143.6 0.2 7.1e-42 143.2 0.1 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 KLO10536.1 - 2.7e-10 40.5 0.2 3.8e-10 40.0 0.2 1.3 1 0 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 KLO10536.1 - 5e-06 25.4 0.0 6.7e-06 25.0 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Semialdhyde_dh PF01118.19 KLO10536.1 - 0.0027 18.0 0.7 0.078 13.2 0.1 2.5 2 1 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain DapB_N PF01113.15 KLO10536.1 - 0.0037 17.1 0.1 0.0079 16.1 0.1 1.5 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus KR PF08659.5 KLO10536.1 - 0.011 15.3 0.2 0.024 14.3 0.2 1.6 1 0 0 1 1 1 0 KR domain adh_short PF00106.20 KLO10536.1 - 0.026 14.4 0.6 0.075 12.9 0.4 1.8 1 0 0 1 1 1 0 short chain dehydrogenase A_deaminase PF00962.17 KLO10537.1 - 1.2e-46 159.1 0.0 6.1e-46 156.8 0.0 1.9 1 1 0 1 1 1 1 Adenosine/AMP deaminase A_deaminase_N PF08451.6 KLO10537.1 - 3.3e-05 23.8 0.0 7.4e-05 22.7 0.0 1.6 1 0 0 1 1 1 1 Adenosine/AMP deaminase N-terminal A_deaminase PF00962.17 KLO10538.1 - 8.6e-45 153.0 0.0 1.9e-44 151.9 0.0 1.5 1 1 0 1 1 1 1 Adenosine/AMP deaminase A_deaminase_N PF08451.6 KLO10538.1 - 2.2e-05 24.3 0.1 4.5e-05 23.3 0.0 1.6 1 0 0 1 1 1 1 Adenosine/AMP deaminase N-terminal Vps54 PF07928.7 KLO10539.1 - 1.6e-51 173.9 1.2 3e-51 173.0 0.2 2.0 2 0 0 2 2 2 1 Vps54-like protein DUF2450 PF10475.4 KLO10539.1 - 0.00022 20.2 0.2 0.00055 18.9 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function N-terminal domain (DUF2450) DUF2451 PF10474.4 KLO10539.1 - 0.00035 20.3 1.3 0.0007 19.4 0.9 1.4 1 0 0 1 1 1 1 Protein of unknown function C-terminus (DUF2451) Tropomyosin_1 PF12718.2 KLO10539.1 - 0.39 10.5 4.4 0.39 10.5 1.0 2.3 2 0 0 2 2 2 0 Tropomyosin like Ecl1 PF12855.2 KLO10541.1 - 6.7e-05 22.0 1.5 0.00013 21.1 1.1 1.5 1 0 0 1 1 1 1 Life-span regulatory factor WD40 PF00400.27 KLO10545.1 - 4.8e-39 130.8 13.8 1.7e-08 34.0 0.2 6.5 6 1 0 6 6 6 5 WD domain, G-beta repeat CLTH PF10607.4 KLO10545.1 - 0.089 12.4 0.0 0.14 11.8 0.0 1.3 1 0 0 1 1 1 0 CTLH/CRA C-terminal to LisH motif domain Cytochrom_D1 PF02239.11 KLO10545.1 - 0.094 10.9 0.0 0.31 9.2 0.0 1.9 2 0 0 2 2 2 0 Cytochrome D1 heme domain DUF4221 PF13970.1 KLO10545.1 - 0.2 10.9 0.0 1.4 8.1 0.0 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4221) Elongin_A PF06881.6 KLO10546.1 - 1.1e-17 64.3 0.1 2.3e-17 63.3 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase II transcription factor SIII (Elongin) subunit A Gti1_Pac2 PF09729.4 KLO10547.1 - 7.2e-28 97.5 0.9 9e-27 93.9 0.6 2.1 1 1 0 1 1 1 1 Gti1/Pac2 family DUF3494 PF11999.3 KLO10547.1 - 0.17 11.4 0.0 0.24 11.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3494) cwf18 PF08315.7 KLO10548.1 - 1.3e-28 100.0 13.9 1.8e-28 99.6 9.6 1.2 1 0 0 1 1 1 1 cwf18 pre-mRNA splicing factor IncFII_repA PF02387.10 KLO10548.1 - 0.56 9.3 5.5 0.5 9.4 3.0 1.4 1 1 0 1 1 1 0 IncFII RepA protein family LepA_C PF06421.7 KLO10549.1 - 9.1e-41 138.1 0.1 1.5e-40 137.3 0.1 1.4 1 0 0 1 1 1 1 GTP-binding protein LepA C-terminus GTP_EFTU PF00009.22 KLO10549.1 - 2.1e-28 99.0 0.0 3.4e-28 98.3 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_C PF00679.19 KLO10549.1 - 5.2e-16 58.2 0.0 1.2e-15 57.1 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 KLO10549.1 - 3.9e-07 30.0 0.1 7.7e-07 29.1 0.1 1.5 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_II PF14492.1 KLO10549.1 - 2.1e-06 27.4 0.0 4.1e-06 26.5 0.0 1.5 1 0 0 1 1 1 1 Elongation Factor G, domain II Ras PF00071.17 KLO10549.1 - 0.0015 17.9 0.0 0.0033 16.8 0.0 1.5 1 0 0 1 1 1 1 Ras family IF-2B PF01008.12 KLO10550.1 - 7.3e-64 215.4 0.0 8.5e-64 215.2 0.0 1.0 1 0 0 1 1 1 1 Initiation factor 2 subunit family Mur_ligase PF01225.20 KLO10550.1 - 0.022 14.8 0.0 0.057 13.4 0.0 1.7 1 0 0 1 1 1 0 Mur ligase family, catalytic domain GATase_2 PF00310.16 KLO10551.1 - 2.6e-26 92.1 0.9 5.3e-20 71.4 0.0 2.2 1 1 1 2 2 2 2 Glutamine amidotransferases class-II GATase_6 PF13522.1 KLO10551.1 - 2.2e-15 56.7 0.0 4.6e-15 55.7 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain Pribosyltran PF00156.22 KLO10551.1 - 8.4e-15 54.5 0.4 1.6e-14 53.7 0.3 1.4 1 0 0 1 1 1 1 Phosphoribosyl transferase domain GATase_7 PF13537.1 KLO10551.1 - 1.4e-13 50.7 0.0 2.3e-13 49.9 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_4 PF13230.1 KLO10551.1 - 1.5e-06 27.1 0.0 3e-06 26.1 0.0 1.4 1 1 0 1 1 1 1 Glutamine amidotransferases class-II Myotub-related PF06602.9 KLO10552.1 - 7.6e-129 429.4 0.1 1.2e-128 428.8 0.1 1.3 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain Y_phosphatase PF00102.22 KLO10552.1 - 0.015 14.6 0.0 0.044 13.1 0.0 1.7 2 0 0 2 2 2 0 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.1 KLO10552.1 - 0.098 12.9 0.2 0.32 11.2 0.0 1.9 2 0 0 2 2 2 0 Tyrosine phosphatase family S-AdoMet_synt_C PF02773.11 KLO10553.1 - 4.7e-76 253.1 0.3 8.3e-76 252.3 0.2 1.4 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, C-terminal domain S-AdoMet_synt_M PF02772.11 KLO10553.1 - 5.9e-49 165.0 0.0 1e-48 164.2 0.0 1.4 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, central domain S-AdoMet_synt_N PF00438.15 KLO10553.1 - 2.7e-44 149.4 1.5 1.5e-43 147.1 0.1 2.2 2 0 0 2 2 2 1 S-adenosylmethionine synthetase, N-terminal domain S-antigen PF05756.6 KLO10553.1 - 0.12 12.3 0.0 0.23 11.4 0.0 1.3 1 0 0 1 1 1 0 S-antigen protein Trp_syntA PF00290.15 KLO10554.1 - 2.6e-81 271.9 0.5 4e-81 271.3 0.4 1.2 1 0 0 1 1 1 1 Tryptophan synthase alpha chain PALP PF00291.20 KLO10554.1 - 1.2e-44 152.8 0.1 1.8e-44 152.2 0.1 1.2 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme His_biosynth PF00977.16 KLO10554.1 - 0.00034 19.9 0.1 0.00085 18.6 0.0 1.6 1 0 0 1 1 1 1 Histidine biosynthesis protein PA PF02225.17 KLO10554.1 - 0.024 14.3 0.7 5.5 6.7 0.0 2.9 2 0 0 2 2 2 0 PA domain PcrB PF01884.12 KLO10554.1 - 0.059 12.6 0.1 0.11 11.6 0.1 1.4 1 0 0 1 1 1 0 PcrB family Asparaginase PF00710.15 KLO10555.1 - 4e-113 377.4 0.0 5e-113 377.1 0.0 1.1 1 0 0 1 1 1 1 Asparaginase Ank PF00023.25 KLO10555.1 - 4.8e-18 63.9 1.8 1.5e-07 30.8 0.1 4.3 4 0 0 4 4 4 2 Ankyrin repeat Ank_2 PF12796.2 KLO10555.1 - 4e-17 62.3 0.2 3.4e-16 59.3 0.0 2.3 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_4 PF13637.1 KLO10555.1 - 1.2e-10 41.5 0.0 5e-07 30.0 0.0 3.1 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 KLO10555.1 - 2.2e-10 39.7 0.4 0.0031 17.6 0.0 3.9 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.1 KLO10555.1 - 6.9e-09 35.6 0.9 2.6e-05 24.3 0.1 3.5 3 1 1 4 4 4 2 Ankyrin repeats (many copies) MbeD_MobD PF04899.7 KLO10556.1 - 0.00013 21.8 12.5 0.0019 18.0 0.4 3.2 3 0 0 3 3 3 2 MbeD/MobD like Csm1 PF12539.3 KLO10556.1 - 0.0074 16.7 0.1 0.018 15.5 0.0 1.7 1 0 0 1 1 1 1 Chromosome segregation protein Csm1/Pcs1 HALZ PF02183.13 KLO10556.1 - 0.011 15.3 7.5 0.03 14.0 1.3 3.2 2 0 0 2 2 2 0 Homeobox associated leucine zipper Reo_sigmaC PF04582.7 KLO10556.1 - 0.015 14.5 3.8 0.024 13.8 2.6 1.3 1 0 0 1 1 1 0 Reovirus sigma C capsid protein ADIP PF11559.3 KLO10556.1 - 0.026 14.4 23.5 0.054 13.3 4.0 2.5 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding Tropomyosin PF00261.15 KLO10556.1 - 0.055 12.5 22.7 0.53 9.3 15.7 2.2 1 1 1 2 2 2 0 Tropomyosin HSCB_C PF07743.8 KLO10556.1 - 0.4 11.1 14.2 0.051 14.0 2.9 3.2 2 1 1 3 3 3 0 HSCB C-terminal oligomerisation domain DUF812 PF05667.6 KLO10556.1 - 2.2 6.6 28.4 0.27 9.7 16.6 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF812) TBPIP PF07106.8 KLO10556.1 - 2.7 7.4 20.0 2.2 7.8 5.6 2.4 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) WXG100 PF06013.7 KLO10556.1 - 3.5 7.6 9.8 4.1 7.4 0.3 3.7 3 0 0 3 3 3 0 Proteins of 100 residues with WXG TMF_DNA_bd PF12329.3 KLO10556.1 - 3.8 7.3 25.0 3.4 7.5 3.7 3.5 2 1 0 2 2 2 0 TATA element modulatory factor 1 DNA binding Fib_alpha PF08702.5 KLO10556.1 - 4.8 7.2 11.5 14 5.7 0.9 2.7 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family Cu_bind_like PF02298.12 KLO10557.1 - 0.0031 17.2 0.3 0.0097 15.6 0.2 1.8 1 1 0 1 1 1 1 Plastocyanin-like domain Copper-bind PF00127.15 KLO10557.1 - 0.0088 16.2 0.1 0.017 15.3 0.1 1.4 1 0 0 1 1 1 1 Copper binding proteins, plastocyanin/azurin family G-gamma PF00631.17 KLO10558.1 - 1.7e-22 78.9 0.0 1.9e-22 78.7 0.0 1.0 1 0 0 1 1 1 1 GGL domain Thioredoxin PF00085.15 KLO10559.1 - 5.7e-28 96.6 0.0 7.5e-28 96.2 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.1 KLO10559.1 - 5.3e-09 36.2 0.1 8.1e-08 32.4 0.0 2.3 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.1 KLO10559.1 - 2.7e-07 30.5 0.0 3.4e-05 23.8 0.0 2.4 2 1 1 3 3 3 2 Thioredoxin-like Thioredoxin_7 PF13899.1 KLO10559.1 - 0.00063 19.7 0.1 0.0014 18.6 0.0 1.8 1 1 0 1 1 1 1 Thioredoxin-like Thioredoxin_9 PF14595.1 KLO10559.1 - 0.0029 17.1 0.0 0.005 16.3 0.0 1.5 1 1 0 1 1 1 1 Thioredoxin AhpC-TSA PF00578.16 KLO10559.1 - 0.0059 16.2 0.1 0.079 12.6 0.0 2.2 1 1 1 3 3 3 1 AhpC/TSA family Redoxin PF08534.5 KLO10559.1 - 0.0095 15.4 0.1 0.064 12.7 0.0 2.0 2 1 0 2 2 2 1 Redoxin Mating_N PF12731.2 KLO10559.1 - 0.032 14.0 0.0 0.055 13.3 0.0 1.4 1 0 0 1 1 1 0 Mating-type protein beta 1 TraF PF13728.1 KLO10559.1 - 0.06 12.8 0.0 0.11 11.9 0.0 1.5 1 1 0 1 1 1 0 F plasmid transfer operon protein DUF836 PF05768.9 KLO10559.1 - 0.12 12.6 0.0 0.21 11.8 0.0 1.4 1 0 0 1 1 1 0 Glutaredoxin-like domain (DUF836) G-gamma PF00631.17 KLO10560.1 - 1.6e-20 72.6 0.0 1.7e-20 72.4 0.0 1.0 1 0 0 1 1 1 1 GGL domain MFS_1 PF07690.11 KLO10562.1 - 7.6e-21 74.2 54.0 4.2e-18 65.1 27.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.2 KLO10562.1 - 0.0084 15.8 5.5 0.33 10.7 0.2 3.5 4 0 0 4 4 4 2 MFS_1 like family Sugar_tr PF00083.19 KLO10562.1 - 8.2 4.8 40.9 0.15 10.6 9.2 3.0 2 2 0 2 2 2 0 Sugar (and other) transporter TRAM_LAG1_CLN8 PF03798.11 KLO10563.1 - 3.3e-31 108.3 13.4 3.3e-31 108.3 9.3 1.6 2 0 0 2 2 2 1 TLC domain GST_C_3 PF14497.1 KLO10564.1 - 0.00015 22.1 0.0 0.00029 21.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 KLO10564.1 - 0.0057 16.5 0.0 0.0096 15.7 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Tom37_C PF11801.3 KLO10564.1 - 0.16 11.8 0.0 0.29 10.9 0.0 1.3 1 0 0 1 1 1 0 Tom37 C-terminal domain Cys_Met_Meta_PP PF01053.15 KLO10565.1 - 9.2e-117 389.5 0.0 1.6e-91 306.4 0.0 2.0 2 0 0 2 2 2 2 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.16 KLO10565.1 - 0.0045 15.9 0.0 0.0071 15.3 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class I and II Met_gamma_lyase PF06838.6 KLO10565.1 - 0.024 12.9 0.0 0.039 12.2 0.0 1.3 1 1 0 1 1 1 0 Methionine gamma-lyase DegT_DnrJ_EryC1 PF01041.12 KLO10565.1 - 0.11 11.5 0.0 0.16 10.9 0.0 1.2 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family EF1_GNE PF00736.14 KLO10566.1 - 2.3e-30 104.1 1.7 4.4e-30 103.2 1.2 1.4 1 0 0 1 1 1 1 EF-1 guanine nucleotide exchange domain EF-1_beta_acid PF10587.4 KLO10566.1 - 8.4e-12 45.0 9.2 8.4e-12 45.0 6.4 2.1 2 0 0 2 2 2 1 Eukaryotic elongation factor 1 beta central acidic region GST_C_3 PF14497.1 KLO10566.1 - 0.00021 21.7 0.0 0.00057 20.3 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 KLO10566.1 - 0.0006 19.7 0.1 0.074 13.0 0.0 2.8 2 1 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 KLO10566.1 - 0.06 13.2 0.0 1 9.3 0.0 2.5 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Dynactin_p22 PF07426.6 KLO10566.1 - 0.43 9.8 3.3 2.9 7.1 2.3 2.0 1 1 0 1 1 1 0 Dynactin subunit p22 Syja_N PF02383.13 KLO10567.1 - 7e-86 287.8 0.0 9.3e-86 287.4 0.0 1.2 1 0 0 1 1 1 1 SacI homology domain hSac2 PF12456.3 KLO10567.1 - 4.6e-25 87.2 0.0 9e-25 86.2 0.0 1.5 1 0 0 1 1 1 1 Inositol phosphatase DUF2346 PF09803.4 KLO10568.1 - 3e-09 36.6 0.1 4.1e-09 36.1 0.1 1.3 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2346) PALP PF00291.20 KLO10569.1 - 7.4e-56 189.6 0.0 8.7e-56 189.3 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Peripla_BP_6 PF13458.1 KLO10569.1 - 0.0092 15.3 0.0 2.9 7.1 0.0 2.2 2 0 0 2 2 2 2 Periplasmic binding protein Glyco_hydro_31 PF01055.21 KLO10570.1 - 1.4e-121 406.3 0.1 1.8e-121 406.0 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.1 KLO10570.1 - 1.3e-19 69.7 0.4 3.5e-19 68.4 0.1 1.9 2 0 0 2 2 2 1 Galactose mutarotase-like zf-MYND PF01753.13 KLO10573.1 - 7.5e-12 44.9 26.1 3.1e-09 36.5 8.0 2.8 3 0 0 3 3 3 2 MYND finger zf-Mss51 PF13824.1 KLO10573.1 - 0.035 13.9 14.1 0.14 12.0 4.0 2.7 2 0 0 2 2 2 0 Zinc-finger of mitochondrial splicing suppressor 51 F-box-like PF12937.2 KLO10577.1 - 3.2e-08 33.1 0.8 3.2e-08 33.1 0.6 2.7 3 0 0 3 3 3 1 F-box-like zf-MYND PF01753.13 KLO10578.1 - 1.4e-10 40.8 19.8 4.7e-08 32.7 5.6 2.7 2 0 0 2 2 2 2 MYND finger zf-Mss51 PF13824.1 KLO10578.1 - 0.09 12.6 15.4 1.3 8.9 0.8 3.3 3 0 0 3 3 3 0 Zinc-finger of mitochondrial splicing suppressor 51 G-alpha PF00503.15 KLO10580.1 - 4.3e-112 374.6 0.0 5.6e-112 374.2 0.0 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 KLO10580.1 - 2.7e-05 23.5 0.0 5.5e-05 22.4 0.0 1.5 1 0 0 1 1 1 1 ADP-ribosylation factor family DUF2945 PF11160.3 KLO10581.1 - 9.9e-05 22.0 0.1 0.0096 15.7 0.1 2.2 1 1 0 1 1 1 1 Protein of unknown function (DUF2945) DUF1918 PF08940.6 KLO10581.1 - 0.0003 20.0 0.0 0.00042 19.5 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1918) Mfa2 PF08842.5 KLO10581.1 - 0.021 14.1 0.4 0.023 14.0 0.3 1.0 1 0 0 1 1 1 0 Fimbrillin-A associated anchor proteins Mfa1 and Mfa2 CBM_5_12 PF02839.9 KLO10581.1 - 0.068 12.7 0.9 0.21 11.2 0.2 2.0 2 0 0 2 2 2 0 Carbohydrate binding domain Cript PF10235.4 KLO10583.1 - 2.7e-21 75.7 5.1 2.7e-21 75.7 3.5 1.5 1 1 0 1 1 1 1 Microtubule-associated protein CRIPT DZR PF12773.2 KLO10583.1 - 0.039 13.7 14.9 0.25 11.2 8.0 2.7 1 1 1 2 2 2 0 Double zinc ribbon DNA_primase_lrg PF04104.9 KLO10583.1 - 0.094 11.9 4.4 0.12 11.6 3.0 1.1 1 0 0 1 1 1 0 Eukaryotic and archaeal DNA primase, large subunit zinc_ribbon_2 PF13240.1 KLO10583.1 - 0.16 11.4 15.9 1.3 8.5 4.6 3.1 3 0 0 3 3 3 0 zinc-ribbon domain zf-ribbon_3 PF13248.1 KLO10583.1 - 0.19 10.9 10.2 0.31 10.3 2.1 3.1 3 0 0 3 3 3 0 zinc-ribbon domain DUF2039 PF10217.4 KLO10583.1 - 0.21 11.6 11.9 0.076 13.0 4.3 2.0 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2039) DUF1272 PF06906.6 KLO10583.1 - 1.8 8.4 7.5 0.68 9.8 2.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1272) DNA_RNApol_7kD PF03604.8 KLO10583.1 - 9.1 5.8 14.2 4.3 6.8 0.5 3.7 3 1 0 3 3 3 0 DNA directed RNA polymerase, 7 kDa subunit HEM4 PF02602.10 KLO10585.1 - 2.7e-31 108.5 0.0 3.4e-31 108.2 0.0 1.1 1 0 0 1 1 1 1 Uroporphyrinogen-III synthase HemD Aldo_ket_red PF00248.16 KLO10586.1 - 1.8e-77 259.9 0.0 2.1e-77 259.7 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Mito_carr PF00153.22 KLO10587.1 - 4.9e-61 202.4 1.3 1.7e-22 78.9 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Myb_DNA-bind_3 PF12776.2 KLO10588.1 - 5.9e-16 58.8 0.4 9.7e-16 58.1 0.3 1.4 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_4 PF13837.1 KLO10588.1 - 2.6e-05 24.2 0.5 4.8e-05 23.4 0.4 1.5 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Abhydrolase_4 PF08386.5 KLO10589.1 - 7.8e-17 61.0 0.0 1.4e-16 60.2 0.0 1.4 1 0 0 1 1 1 1 TAP-like protein Abhydrolase_1 PF00561.15 KLO10589.1 - 4.9e-15 55.7 0.0 4.9e-10 39.3 0.0 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 KLO10589.1 - 0.01 15.7 0.0 0.06 13.2 0.0 2.3 1 1 0 1 1 1 0 Alpha/beta hydrolase family zf-MYND PF01753.13 KLO10590.1 - 1.8e-08 34.1 16.3 1.8e-08 34.1 11.3 2.2 2 0 0 2 2 2 1 MYND finger zf-MYND PF01753.13 KLO10592.1 - 3.7e-10 39.4 25.2 5e-08 32.6 7.0 3.0 3 0 0 3 3 3 2 MYND finger zf-Mss51 PF13824.1 KLO10592.1 - 3 7.7 12.2 5.5 6.9 0.9 2.8 2 0 0 2 2 2 0 Zinc-finger of mitochondrial splicing suppressor 51 Ecl1 PF12855.2 KLO10592.1 - 3.1 7.1 10.9 11 5.3 7.5 1.9 1 0 0 1 1 1 0 Life-span regulatory factor zf-MYND PF01753.13 KLO10594.1 - 2.4e-07 30.5 20.2 2.5e-06 27.2 1.8 3.0 3 0 0 3 3 3 2 MYND finger Chlamy_scaf PF09675.5 KLO10594.1 - 0.012 15.6 0.0 0.021 14.8 0.0 1.3 1 0 0 1 1 1 0 Chlamydia-phage Chp2 scaffold (Chlamy_scaf) zf-Mss51 PF13824.1 KLO10594.1 - 0.67 9.8 13.4 0.59 10.0 1.5 2.7 2 0 0 2 2 2 0 Zinc-finger of mitochondrial splicing suppressor 51 zf-MYND PF01753.13 KLO10596.1 - 1.5e-07 31.1 24.2 1.7e-06 27.7 5.2 3.3 3 0 0 3 3 3 2 MYND finger zf-MYND PF01753.13 KLO10598.1 - 2.3e-09 36.9 23.2 2.4e-08 33.7 4.0 3.1 3 1 0 3 3 3 2 MYND finger Chlamy_scaf PF09675.5 KLO10598.1 - 0.16 12.0 0.0 0.29 11.1 0.0 1.4 1 0 0 1 1 1 0 Chlamydia-phage Chp2 scaffold (Chlamy_scaf) zf-MYND PF01753.13 KLO10600.1 - 7.1e-09 35.4 22.2 1.3e-07 31.3 4.0 3.2 3 1 0 3 3 3 2 MYND finger zf-MYND PF01753.13 KLO10601.1 - 2.8e-09 36.6 22.2 2.6e-07 30.4 4.0 2.9 3 0 0 3 3 3 2 MYND finger zf-Mss51 PF13824.1 KLO10601.1 - 0.019 14.7 11.0 0.87 9.4 1.1 2.8 2 0 0 2 2 2 0 Zinc-finger of mitochondrial splicing suppressor 51 UPF0547 PF10571.4 KLO10601.1 - 2.3 7.9 8.2 9.3 6.0 0.7 3.0 2 0 0 2 2 2 0 Uncharacterised protein family UPF0547 RTA1 PF04479.8 KLO10602.1 - 9.2e-46 156.1 3.4 9.2e-46 156.1 2.4 1.4 2 0 0 2 2 2 1 RTA1 like protein zf-MYND PF01753.13 KLO10604.1 - 7e-09 35.4 17.7 7e-09 35.4 12.3 2.3 2 0 0 2 2 2 1 MYND finger SfsA PF03749.8 KLO10604.1 - 0.017 14.5 0.0 0.03 13.7 0.0 1.3 1 0 0 1 1 1 0 Sugar fermentation stimulation protein Abhydrolase_4 PF08386.5 KLO10605.1 - 5.8e-18 64.6 0.0 1e-17 63.8 0.0 1.4 1 0 0 1 1 1 1 TAP-like protein Abhydrolase_1 PF00561.15 KLO10605.1 - 3.4e-14 52.9 0.0 1.1e-10 41.4 0.0 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 KLO10605.1 - 0.0004 20.3 0.0 0.002 18.0 0.0 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_4 PF08386.5 KLO10606.1 - 1.5e-14 53.7 0.0 3.2e-14 52.6 0.0 1.6 1 0 0 1 1 1 1 TAP-like protein Abhydrolase_1 PF00561.15 KLO10606.1 - 7.3e-14 51.8 0.0 1.4e-10 41.0 0.0 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 KLO10606.1 - 1.8e-05 24.7 0.0 4.1e-05 23.5 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family RNA_lig_T4_1 PF09511.5 KLO10607.1 - 1.9e-72 243.3 0.0 4.9e-72 242.0 0.0 1.7 2 0 0 2 2 2 1 RNA ligase tRNA_lig_kinase PF08303.6 KLO10607.1 - 4.1e-28 98.3 0.4 9e-28 97.2 0.3 1.5 1 0 0 1 1 1 1 tRNA ligase kinase domain tRNA_lig_CPD PF08302.6 KLO10607.1 - 4e-15 55.7 0.0 3.3e-14 52.7 0.0 2.4 1 1 0 2 2 2 1 Fungal tRNA ligase phosphodiesterase domain AAA_17 PF13207.1 KLO10607.1 - 0.00062 20.5 0.1 0.0025 18.5 0.0 2.1 1 0 0 1 1 1 1 AAA domain WD40 PF00400.27 KLO10608.1 - 2.1e-05 24.2 0.1 0.0029 17.4 0.1 2.6 2 0 0 2 2 2 2 WD domain, G-beta repeat Hira PF07569.6 KLO10608.1 - 0.11 11.7 0.8 0.74 8.9 0.0 2.3 3 0 0 3 3 3 0 TUP1-like enhancer of split SET PF00856.23 KLO10609.1 - 1.9e-09 37.9 0.0 5.1e-09 36.6 0.0 1.8 1 1 0 1 1 1 1 SET domain NAP PF00956.13 KLO10610.1 - 0.15 11.1 1.4 0.18 10.8 0.0 1.7 2 0 0 2 2 2 0 Nucleosome assembly protein (NAP) Exo70 PF03081.10 KLO10611.1 - 3e-39 134.8 0.0 5e-39 134.1 0.0 1.3 1 0 0 1 1 1 1 Exo70 exocyst complex subunit BP28CT PF08146.7 KLO10611.1 - 0.01 15.5 0.1 0.099 12.3 0.0 2.6 3 0 0 3 3 3 0 BP28CT (NUC211) domain Snapin_Pallidin PF14712.1 KLO10611.1 - 0.16 12.3 3.7 0.21 11.8 0.6 2.5 2 0 0 2 2 2 0 Snapin/Pallidin Abhydrolase_1 PF00561.15 KLO10612.1 - 4.7e-17 62.3 0.1 6.6e-17 61.8 0.1 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 KLO10612.1 - 0.0002 21.3 0.0 0.0004 20.3 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Gelsolin PF00626.17 KLO10614.1 - 4.7e-32 109.5 0.0 7.9e-15 54.3 0.0 3.2 3 0 0 3 3 3 3 Gelsolin repeat zf-C2H2 PF00096.21 KLO10615.1 - 6.7e-12 44.9 10.0 6.6e-06 26.1 1.1 2.1 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 KLO10615.1 - 1.4e-10 40.8 17.3 3.9e-08 33.2 2.2 3.1 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 KLO10615.1 - 4.5e-09 36.0 9.3 0.00014 21.8 1.3 2.1 2 0 0 2 2 2 2 C2H2-type zinc finger zf-TRAF PF02176.13 KLO10615.1 - 0.0018 18.5 1.4 0.002 18.4 1.0 1.1 1 0 0 1 1 1 1 TRAF-type zinc finger Ogr_Delta PF04606.7 KLO10615.1 - 0.073 12.7 0.6 3.1 7.5 0.2 2.1 1 1 1 2 2 2 0 Ogr/Delta-like zinc finger CHORD PF04968.7 KLO10615.1 - 0.12 12.6 2.2 1.1 9.5 0.1 2.0 1 1 1 2 2 2 0 CHORD RPAP2_Rtr1 PF04181.8 KLO10615.1 - 0.14 12.2 0.2 2.6 8.2 0.0 2.0 1 1 1 2 2 2 0 Rtr1/RPAP2 family zf-UBP PF02148.14 KLO10615.1 - 0.18 11.9 3.4 5.2 7.2 2.3 2.1 1 1 0 1 1 1 0 Zn-finger in ubiquitin-hydrolases and other protein zf-C2H2_jaz PF12171.3 KLO10615.1 - 5.3 7.3 5.5 28 5.0 0.2 2.7 3 1 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 KLO10615.1 - 6 6.9 6.1 7.8 6.5 0.1 2.8 2 1 0 2 2 2 0 C2H2-type zinc finger Erv26 PF04148.8 KLO10616.1 - 0.016 14.6 1.6 0.017 14.4 1.1 1.0 1 0 0 1 1 1 0 Transmembrane adaptor Erv26 WD40 PF00400.27 KLO10617.1 - 1.2e-26 91.5 14.3 9.3e-09 34.8 0.0 7.1 7 0 0 7 7 7 6 WD domain, G-beta repeat APS_kinase PF01583.15 KLO10619.1 - 0.00023 20.8 0.1 0.0003 20.4 0.1 1.2 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_19 PF13245.1 KLO10619.1 - 0.0015 18.1 0.0 0.0027 17.4 0.0 1.4 2 0 0 2 2 2 1 Part of AAA domain AAA_16 PF13191.1 KLO10619.1 - 0.0019 18.1 0.0 0.002 18.1 0.0 1.1 1 0 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.1 KLO10619.1 - 0.0046 16.4 0.1 0.0075 15.7 0.1 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain NACHT PF05729.7 KLO10619.1 - 0.0098 15.5 0.0 0.01 15.4 0.0 1.2 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.1 KLO10619.1 - 0.014 15.5 0.0 0.016 15.3 0.0 1.2 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.17 KLO10619.1 - 0.015 14.1 0.0 0.015 14.1 0.0 1.1 1 0 0 1 1 1 0 NB-ARC domain ABC_tran PF00005.22 KLO10619.1 - 0.016 15.4 0.0 0.019 15.2 0.0 1.2 1 0 0 1 1 1 0 ABC transporter AAA_33 PF13671.1 KLO10619.1 - 0.025 14.4 0.1 0.032 14.0 0.1 1.2 1 0 0 1 1 1 0 AAA domain Parvo_NS1 PF01057.12 KLO10619.1 - 0.029 13.2 0.0 0.033 13.0 0.0 1.1 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_17 PF13207.1 KLO10619.1 - 0.07 13.9 0.0 0.084 13.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain UPF0079 PF02367.12 KLO10619.1 - 0.073 12.6 0.0 0.091 12.3 0.0 1.1 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 Thymidylate_kin PF02223.12 KLO10619.1 - 0.077 12.3 0.0 0.11 11.8 0.0 1.2 1 0 0 1 1 1 0 Thymidylate kinase AAA_30 PF13604.1 KLO10619.1 - 0.098 12.2 0.0 0.12 11.9 0.0 1.1 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 KLO10619.1 - 0.11 12.6 0.0 0.16 12.1 0.0 1.4 1 0 0 1 1 1 0 RNA helicase AAA_10 PF12846.2 KLO10619.1 - 0.14 11.5 0.0 0.14 11.5 0.0 1.1 1 0 0 1 1 1 0 AAA-like domain DAP3 PF10236.4 KLO10619.1 - 0.15 10.9 0.0 0.18 10.6 0.0 1.1 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 NACHT PF05729.7 KLO10620.1 - 5.9e-05 22.7 0.9 0.00023 20.8 0.6 1.8 1 1 0 1 1 1 1 NACHT domain AAA_22 PF13401.1 KLO10620.1 - 0.0024 17.9 0.0 0.0038 17.3 0.0 1.2 1 0 0 1 1 1 1 AAA domain KAP_NTPase PF07693.9 KLO10620.1 - 0.0062 15.5 0.3 0.0067 15.4 0.2 1.3 1 1 0 1 1 1 1 KAP family P-loop domain NACHT PF05729.7 KLO10621.1 - 5.7e-07 29.3 1.9 5.9e-06 26.0 1.3 2.1 1 1 0 1 1 1 1 NACHT domain AAA_17 PF13207.1 KLO10621.1 - 0.011 16.6 0.0 0.017 15.9 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA_22 PF13401.1 KLO10621.1 - 0.012 15.7 0.2 0.023 14.8 0.1 1.7 1 1 0 1 1 1 0 AAA domain AAA_33 PF13671.1 KLO10621.1 - 0.034 14.0 0.2 0.063 13.1 0.1 1.4 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.1 KLO10621.1 - 0.097 12.2 0.0 0.15 11.5 0.0 1.2 1 0 0 1 1 1 0 AAA domain Ribosomal_S30 PF04758.9 KLO10621.1 - 0.1 12.3 0.3 12 5.7 0.0 2.3 2 0 0 2 2 2 0 Ribosomal protein S30 AAA_16 PF13191.1 KLO10621.1 - 0.11 12.5 0.4 1.7 8.5 0.3 2.2 1 1 0 1 1 1 0 AAA ATPase domain AAA_19 PF13245.1 KLO10621.1 - 0.13 11.9 0.0 0.93 9.2 0.0 2.1 2 0 0 2 2 2 0 Part of AAA domain RNA_helicase PF00910.17 KLO10621.1 - 0.18 12.0 0.3 0.85 9.8 0.1 2.0 2 0 0 2 2 2 0 RNA helicase Parvo_NS1 PF01057.12 KLO10622.1 - 0.00074 18.4 0.0 0.00074 18.4 0.0 1.0 1 0 0 1 1 1 1 Parvovirus non-structural protein NS1 NACHT PF05729.7 KLO10623.1 - 1e-17 64.2 0.1 1.8e-10 40.7 0.0 2.5 2 0 0 2 2 2 2 NACHT domain AAA_16 PF13191.1 KLO10623.1 - 3e-09 37.1 1.4 4.5e-05 23.5 0.1 3.8 2 2 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.1 KLO10623.1 - 6.3e-09 36.0 0.0 0.00024 21.2 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA PF00004.24 KLO10623.1 - 1.7e-06 28.2 0.0 0.0011 19.2 0.0 2.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) KAP_NTPase PF07693.9 KLO10623.1 - 1.9e-05 23.8 0.1 0.00068 18.7 0.0 2.4 2 0 0 2 2 2 1 KAP family P-loop domain NB-ARC PF00931.17 KLO10623.1 - 4.5e-05 22.4 0.0 0.14 10.9 0.0 2.4 2 0 0 2 2 2 2 NB-ARC domain AAA_19 PF13245.1 KLO10623.1 - 0.00055 19.6 0.0 0.05 13.3 0.0 2.7 2 0 0 2 2 2 1 Part of AAA domain Zeta_toxin PF06414.7 KLO10623.1 - 0.004 16.2 0.1 0.55 9.2 0.0 2.7 3 0 0 3 3 3 1 Zeta toxin APS_kinase PF01583.15 KLO10623.1 - 0.0077 15.9 0.3 0.12 12.0 0.0 2.3 2 0 0 2 2 2 1 Adenylylsulphate kinase PIF1 PF05970.9 KLO10623.1 - 0.0082 15.1 0.1 0.57 9.0 0.0 2.9 3 0 0 3 3 3 1 PIF1-like helicase Parvo_NS1 PF01057.12 KLO10623.1 - 0.013 14.3 0.2 0.47 9.2 0.0 2.3 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 AAA_30 PF13604.1 KLO10623.1 - 0.015 14.8 0.0 0.14 11.7 0.0 2.3 2 0 0 2 2 2 0 AAA domain Torsin PF06309.6 KLO10623.1 - 0.019 14.8 0.0 1.7 8.5 0.0 2.4 2 0 0 2 2 2 0 Torsin ABC_tran PF00005.22 KLO10623.1 - 0.037 14.3 0.0 0.18 12.0 0.0 2.2 2 0 0 2 2 1 0 ABC transporter AAA_17 PF13207.1 KLO10623.1 - 0.042 14.6 0.0 0.89 10.3 0.0 3.0 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.1 KLO10623.1 - 0.077 13.3 0.0 0.37 11.1 0.0 2.3 1 0 0 1 1 1 0 AAA domain NACHT PF05729.7 KLO10624.1 - 2.8e-19 69.3 1.1 2.3e-08 33.8 0.0 2.9 3 0 0 3 3 3 2 NACHT domain AAA_22 PF13401.1 KLO10624.1 - 1.7e-08 34.6 0.0 0.00016 21.8 0.0 3.0 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.1 KLO10624.1 - 1.2e-06 28.7 4.3 0.0038 17.2 0.1 3.7 2 2 0 2 2 2 2 AAA ATPase domain AAA PF00004.24 KLO10624.1 - 1.9e-05 24.8 0.4 0.0034 17.5 0.0 3.2 3 2 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) KAP_NTPase PF07693.9 KLO10624.1 - 0.00025 20.1 0.9 0.013 14.5 0.0 2.6 2 1 0 2 2 2 1 KAP family P-loop domain NB-ARC PF00931.17 KLO10624.1 - 0.00033 19.6 0.5 0.24 10.2 0.0 3.0 3 0 0 3 3 3 2 NB-ARC domain AAA_19 PF13245.1 KLO10624.1 - 0.002 17.8 0.0 0.01 15.5 0.0 2.2 2 0 0 2 2 2 1 Part of AAA domain Parvo_NS1 PF01057.12 KLO10624.1 - 0.002 17.0 0.2 0.36 9.6 0.1 2.3 2 0 0 2 2 2 1 Parvovirus non-structural protein NS1 APS_kinase PF01583.15 KLO10624.1 - 0.0034 17.0 0.4 0.037 13.6 0.1 2.2 2 0 0 2 2 2 1 Adenylylsulphate kinase Torsin PF06309.6 KLO10624.1 - 0.0098 15.7 0.0 1.1 9.1 0.0 3.4 3 0 0 3 3 3 1 Torsin ABC_tran PF00005.22 KLO10624.1 - 0.014 15.6 0.1 0.051 13.8 0.0 2.0 2 0 0 2 2 1 0 ABC transporter PIF1 PF05970.9 KLO10624.1 - 0.028 13.3 0.0 0.094 11.6 0.0 1.8 2 0 0 2 2 2 0 PIF1-like helicase AAA_17 PF13207.1 KLO10624.1 - 0.03 15.1 1.0 0.15 12.9 0.1 2.7 2 1 0 2 2 2 0 AAA domain AAA_18 PF13238.1 KLO10624.1 - 0.062 13.6 0.0 0.48 10.7 0.0 2.6 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.17 KLO10624.1 - 0.068 13.3 0.0 1.6 8.8 0.0 2.5 2 0 0 2 2 2 0 RNA helicase AAA_30 PF13604.1 KLO10624.1 - 0.091 12.3 0.0 0.23 11.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.1 KLO10624.1 - 0.19 11.0 0.9 2 7.7 0.0 2.8 3 1 0 3 3 3 0 AAA domain AAA_16 PF13191.1 KLO10625.1 - 0.006 16.5 0.1 0.027 14.4 0.1 2.1 1 0 0 1 1 1 1 AAA ATPase domain NACHT PF05729.7 KLO10626.1 - 3.5e-10 39.7 0.1 2.4e-09 37.0 0.0 2.4 2 1 0 2 2 2 1 NACHT domain AAA_22 PF13401.1 KLO10626.1 - 3.5e-06 27.1 0.1 0.00075 19.6 0.0 3.0 3 0 0 3 3 3 1 AAA domain AAA_16 PF13191.1 KLO10626.1 - 0.00039 20.4 0.0 0.0019 18.2 0.0 2.2 1 1 0 1 1 1 1 AAA ATPase domain AAA PF00004.24 KLO10626.1 - 0.0005 20.2 0.0 0.0019 18.3 0.0 2.0 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ABC_tran PF00005.22 KLO10626.1 - 0.0099 16.1 0.0 0.032 14.5 0.0 1.9 2 0 0 2 2 2 1 ABC transporter APS_kinase PF01583.15 KLO10626.1 - 0.015 14.9 0.1 0.032 13.8 0.1 1.5 1 0 0 1 1 1 0 Adenylylsulphate kinase NB-ARC PF00931.17 KLO10626.1 - 0.018 13.9 0.0 0.055 12.3 0.0 1.8 1 0 0 1 1 1 0 NB-ARC domain AAA_19 PF13245.1 KLO10626.1 - 0.043 13.5 0.0 0.14 11.9 0.0 1.8 1 0 0 1 1 1 0 Part of AAA domain AAA_30 PF13604.1 KLO10626.1 - 0.077 12.5 0.1 0.16 11.4 0.1 1.5 1 0 0 1 1 1 0 AAA domain Torsin PF06309.6 KLO10626.1 - 0.1 12.4 0.0 0.28 11.0 0.0 1.6 1 0 0 1 1 1 0 Torsin AAA_14 PF13173.1 KLO10626.1 - 0.15 11.9 0.4 18 5.2 0.0 3.3 2 1 0 2 2 2 0 AAA domain AAA_17 PF13207.1 KLO10626.1 - 2.6 8.9 6.1 2.4 9.0 0.1 2.9 2 1 1 3 3 2 0 AAA domain NACHT PF05729.7 KLO10627.1 - 4.1e-09 36.3 0.2 3.5e-08 33.2 0.1 2.4 2 1 0 2 2 2 1 NACHT domain AAA_16 PF13191.1 KLO10627.1 - 3.5e-07 30.3 0.1 5.6e-06 26.4 0.0 2.5 2 1 0 2 2 1 1 AAA ATPase domain AAA_10 PF12846.2 KLO10627.1 - 6.3e-05 22.5 0.0 0.00013 21.5 0.0 1.4 1 1 0 1 1 1 1 AAA-like domain AAA_22 PF13401.1 KLO10627.1 - 0.00025 21.1 0.0 0.00079 19.5 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 KLO10627.1 - 0.002 18.9 1.8 0.18 12.6 0.0 3.0 3 1 0 3 3 3 1 AAA domain AAA_29 PF13555.1 KLO10627.1 - 0.0022 17.4 0.1 0.0045 16.4 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain ABC_tran PF00005.22 KLO10627.1 - 0.0041 17.4 0.0 0.0085 16.3 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AAA_19 PF13245.1 KLO10627.1 - 0.0093 15.6 0.0 0.027 14.2 0.0 1.7 1 0 0 1 1 1 1 Part of AAA domain Rad17 PF03215.10 KLO10627.1 - 0.011 14.5 0.0 0.016 13.8 0.0 1.2 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein AAA_23 PF13476.1 KLO10627.1 - 0.012 15.9 0.1 0.029 14.6 0.1 1.6 1 0 0 1 1 1 0 AAA domain T2SE PF00437.15 KLO10627.1 - 0.021 13.7 0.1 0.038 12.8 0.1 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein RNA_helicase PF00910.17 KLO10627.1 - 0.025 14.7 0.0 0.078 13.1 0.0 1.9 2 0 0 2 2 1 0 RNA helicase AAA_25 PF13481.1 KLO10627.1 - 0.029 13.7 0.1 0.91 8.8 0.0 2.6 2 0 0 2 2 2 0 AAA domain DUF258 PF03193.11 KLO10627.1 - 0.067 12.3 0.0 0.26 10.4 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function, DUF258 DAP3 PF10236.4 KLO10627.1 - 0.07 12.0 0.0 0.13 11.1 0.0 1.4 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 NTPase_1 PF03266.10 KLO10627.1 - 0.085 12.5 0.0 0.17 11.6 0.0 1.5 1 0 0 1 1 1 0 NTPase AAA PF00004.24 KLO10627.1 - 0.085 13.0 0.5 0.39 10.9 0.4 2.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) 5-FTHF_cyc-lig PF01812.15 KLO10627.1 - 0.086 12.6 0.0 0.25 11.0 0.0 1.7 2 0 0 2 2 2 0 5-formyltetrahydrofolate cyclo-ligase family KAP_NTPase PF07693.9 KLO10627.1 - 0.1 11.5 0.1 1.7 7.5 0.0 2.3 2 0 0 2 2 2 0 KAP family P-loop domain UPF0079 PF02367.12 KLO10627.1 - 0.11 12.0 0.0 0.25 11.0 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 AAA_PrkA PF08298.6 KLO10627.1 - 0.12 11.0 0.0 0.21 10.2 0.0 1.3 1 0 0 1 1 1 0 PrkA AAA domain MobB PF03205.9 KLO10627.1 - 0.12 12.1 0.0 0.27 10.9 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_30 PF13604.1 KLO10627.1 - 0.15 11.6 0.1 0.32 10.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain ArgK PF03308.11 KLO10627.1 - 0.16 10.7 0.0 0.27 9.9 0.0 1.3 1 0 0 1 1 1 0 ArgK protein APS_kinase PF01583.15 KLO10627.1 - 0.16 11.5 0.1 0.3 10.7 0.0 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase NACHT PF05729.7 KLO10628.1 - 1.1e-05 25.1 2.9 1.5e-05 24.7 0.3 2.0 2 1 0 2 2 2 1 NACHT domain AAA_22 PF13401.1 KLO10628.1 - 0.0028 17.8 0.0 0.0048 17.0 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 KLO10628.1 - 0.021 14.8 1.8 0.32 10.9 1.2 2.0 1 1 0 1 1 1 0 AAA ATPase domain NB-ARC PF00931.17 KLO10628.1 - 0.032 13.0 0.0 0.039 12.8 0.0 1.1 1 0 0 1 1 1 0 NB-ARC domain AAA PF00004.24 KLO10628.1 - 0.061 13.5 0.0 0.21 11.7 0.0 1.9 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) NACHT PF05729.7 KLO10629.1 - 4.3e-10 39.5 0.1 1.4e-09 37.8 0.0 1.9 2 1 0 2 2 2 1 NACHT domain AAA_22 PF13401.1 KLO10629.1 - 1.2e-05 25.4 0.1 0.00043 20.4 0.0 2.8 3 1 0 3 3 3 1 AAA domain AAA_16 PF13191.1 KLO10629.1 - 6e-05 23.1 0.3 0.00023 21.1 0.1 2.0 1 1 1 2 2 2 1 AAA ATPase domain AAA_19 PF13245.1 KLO10629.1 - 0.0004 20.0 0.0 0.0019 17.9 0.0 2.1 2 0 0 2 2 2 1 Part of AAA domain APS_kinase PF01583.15 KLO10629.1 - 0.0014 18.3 0.0 0.0025 17.4 0.0 1.4 1 0 0 1 1 1 1 Adenylylsulphate kinase ABC_tran PF00005.22 KLO10629.1 - 0.0017 18.6 0.0 0.0037 17.5 0.0 1.7 1 0 0 1 1 1 1 ABC transporter AAA_30 PF13604.1 KLO10629.1 - 0.0028 17.2 0.0 0.0065 16.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA PF00004.24 KLO10629.1 - 0.0035 17.5 0.0 0.017 15.3 0.0 2.1 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 KLO10629.1 - 0.0054 17.5 2.1 0.1 13.4 0.1 2.7 1 1 0 2 2 2 1 AAA domain PIF1 PF05970.9 KLO10629.1 - 0.0069 15.3 0.0 0.012 14.6 0.0 1.3 1 0 0 1 1 1 1 PIF1-like helicase Parvo_NS1 PF01057.12 KLO10629.1 - 0.011 14.5 0.1 0.021 13.7 0.1 1.4 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_18 PF13238.1 KLO10629.1 - 0.011 16.0 0.2 0.31 11.3 0.0 2.7 3 0 0 3 3 3 0 AAA domain AAA_PrkA PF08298.6 KLO10629.1 - 0.02 13.6 0.0 0.028 13.1 0.0 1.2 1 0 0 1 1 1 0 PrkA AAA domain UPF0079 PF02367.12 KLO10629.1 - 0.026 14.1 0.0 0.064 12.8 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 Torsin PF06309.6 KLO10629.1 - 0.029 14.2 0.0 0.1 12.5 0.0 1.9 2 0 0 2 2 2 0 Torsin NB-ARC PF00931.17 KLO10629.1 - 0.03 13.1 2.1 0.088 11.6 0.1 2.6 2 1 0 2 2 2 0 NB-ARC domain IstB_IS21 PF01695.12 KLO10629.1 - 0.061 12.7 0.1 1.3 8.3 0.0 2.3 2 0 0 2 2 2 0 IstB-like ATP binding protein Thymidylate_kin PF02223.12 KLO10629.1 - 0.064 12.6 0.0 0.15 11.3 0.0 1.7 1 0 0 1 1 1 0 Thymidylate kinase AAA_33 PF13671.1 KLO10629.1 - 0.068 13.0 0.0 0.14 12.0 0.0 1.7 1 1 0 1 1 1 0 AAA domain Abhydrolase_4 PF08386.5 KLO10632.1 - 1.3e-14 53.9 0.1 3.6e-14 52.5 0.1 1.7 1 1 0 1 1 1 1 TAP-like protein Abhydrolase_1 PF00561.15 KLO10632.1 - 3.1e-13 49.8 0.2 8.6e-13 48.3 0.1 1.7 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 KLO10632.1 - 0.029 14.2 0.0 0.057 13.2 0.0 1.6 1 1 0 1 1 1 0 Alpha/beta hydrolase family NAD_binding_1 PF00175.16 KLO10633.1 - 0.00079 19.9 0.0 0.0054 17.2 0.0 2.3 1 1 0 1 1 1 1 Oxidoreductase NAD-binding domain Pyridox_oxidase PF01243.15 KLO10633.1 - 0.001 19.0 0.0 0.31 11.0 0.0 2.6 2 1 0 2 2 2 2 Pyridoxamine 5'-phosphate oxidase NAD_binding_6 PF08030.7 KLO10633.1 - 0.0033 17.3 0.0 0.0072 16.2 0.0 1.5 1 0 0 1 1 1 1 Ferric reductase NAD binding domain NACHT PF05729.7 KLO10635.1 - 7.4e-15 54.9 0.1 7.7e-10 38.6 0.0 3.4 3 1 0 3 3 3 2 NACHT domain AAA_22 PF13401.1 KLO10635.1 - 1.1e-12 48.2 0.0 8.5e-05 22.7 0.0 3.0 3 0 0 3 3 2 2 AAA domain AAA_16 PF13191.1 KLO10635.1 - 3.6e-08 33.6 0.7 0.03 14.3 0.1 4.8 4 2 0 4 4 4 2 AAA ATPase domain Parvo_NS1 PF01057.12 KLO10635.1 - 2.4e-06 26.6 0.1 0.03 13.1 0.0 2.3 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 AAA_25 PF13481.1 KLO10635.1 - 0.00012 21.5 0.0 0.12 11.7 0.0 2.8 2 0 0 2 2 2 2 AAA domain RNA_helicase PF00910.17 KLO10635.1 - 0.00017 21.7 0.0 0.22 11.7 0.0 2.7 2 0 0 2 2 2 2 RNA helicase AAA_30 PF13604.1 KLO10635.1 - 0.00017 21.2 0.3 0.033 13.7 0.1 2.4 2 0 0 2 2 2 1 AAA domain NB-ARC PF00931.17 KLO10635.1 - 0.00035 19.5 0.0 0.046 12.5 0.0 3.3 3 0 0 3 3 3 1 NB-ARC domain AAA_19 PF13245.1 KLO10635.1 - 0.00042 20.0 0.0 0.015 15.0 0.0 2.5 2 0 0 2 2 2 1 Part of AAA domain AAA_17 PF13207.1 KLO10635.1 - 0.00052 20.8 0.9 0.18 12.6 0.1 3.6 3 1 0 3 3 3 1 AAA domain AAA PF00004.24 KLO10635.1 - 0.0007 19.8 0.3 0.24 11.6 0.0 3.2 3 1 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) APS_kinase PF01583.15 KLO10635.1 - 0.0026 17.4 0.5 0.48 10.0 0.1 2.6 2 0 0 2 2 2 1 Adenylylsulphate kinase AAA_18 PF13238.1 KLO10635.1 - 0.0035 17.6 0.1 0.34 11.2 0.0 3.6 3 0 0 3 3 3 1 AAA domain ABC_tran PF00005.22 KLO10635.1 - 0.0096 16.2 0.0 0.12 12.6 0.0 2.7 3 0 0 3 3 3 1 ABC transporter IstB_IS21 PF01695.12 KLO10635.1 - 0.012 15.0 0.0 0.6 9.4 0.0 2.8 2 0 0 2 2 2 0 IstB-like ATP binding protein MobB PF03205.9 KLO10635.1 - 0.012 15.3 0.2 2.2 7.9 0.0 2.8 3 0 0 3 3 2 0 Molybdopterin guanine dinucleotide synthesis protein B Sigma54_activ_2 PF14532.1 KLO10635.1 - 0.014 15.4 0.0 0.056 13.4 0.0 2.1 2 0 0 2 2 1 0 Sigma-54 interaction domain AAA_29 PF13555.1 KLO10635.1 - 0.025 14.0 0.0 2.3 7.8 0.0 2.5 2 0 0 2 2 2 0 P-loop containing region of AAA domain NTPase_1 PF03266.10 KLO10635.1 - 0.038 13.7 0.0 5.3 6.7 0.0 2.5 2 0 0 2 2 2 0 NTPase AAA_14 PF13173.1 KLO10635.1 - 0.048 13.5 0.1 32 4.4 0.0 4.0 2 2 0 2 2 2 0 AAA domain PhoH PF02562.11 KLO10635.1 - 0.06 12.5 0.0 2.4 7.3 0.0 2.3 2 0 0 2 2 2 0 PhoH-like protein PSS PF03034.10 KLO10635.1 - 0.075 12.4 3.6 0.59 9.4 0.1 2.5 3 0 0 3 3 3 0 Phosphatidyl serine synthase adh_short PF00106.20 KLO10636.1 - 3.1e-27 95.5 2.6 3.8e-27 95.2 1.4 1.4 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.1 KLO10636.1 - 4.4e-14 52.8 0.1 5.6e-14 52.4 0.1 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KLO10636.1 - 4.7e-14 52.4 1.1 8.2e-14 51.6 0.8 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 KLO10636.1 - 5e-05 22.8 0.1 7.7e-05 22.2 0.1 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.3 KLO10636.1 - 0.0013 18.4 0.2 0.0097 15.6 0.1 2.4 2 0 0 2 2 2 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase 3HCDH_N PF02737.13 KLO10636.1 - 0.0015 18.2 2.4 0.0024 17.5 0.6 2.0 2 1 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ApbA PF02558.11 KLO10636.1 - 0.0018 17.7 0.1 0.0035 16.8 0.1 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA NAD_binding_10 PF13460.1 KLO10636.1 - 0.0022 18.0 1.8 0.0042 17.1 1.2 1.7 1 1 0 1 1 1 1 NADH(P)-binding 2-Hacid_dh_C PF02826.14 KLO10636.1 - 0.003 16.7 0.1 0.076 12.1 0.0 2.3 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Shikimate_DH PF01488.15 KLO10636.1 - 0.004 17.2 0.2 0.0088 16.1 0.1 1.6 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase THF_DHG_CYH_C PF02882.14 KLO10636.1 - 0.033 13.2 0.0 0.083 11.9 0.0 1.7 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Dak1_2 PF13684.1 KLO10636.1 - 0.083 11.8 0.0 0.24 10.2 0.0 1.6 2 0 0 2 2 2 0 Dihydroxyacetone kinase family DFP PF04127.10 KLO10636.1 - 0.15 11.6 1.0 0.48 10.0 0.7 1.7 1 1 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein Abhydrolase_6 PF12697.2 KLO10637.1 - 0.0026 17.6 0.2 0.004 17.0 0.1 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family RRM_6 PF14259.1 KLO10637.1 - 0.0032 17.3 0.0 0.51 10.3 0.0 2.7 2 1 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) DUF829 PF05705.9 KLO10637.1 - 0.0068 16.1 0.0 0.012 15.2 0.0 1.4 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF829) DUF676 PF05057.9 KLO10637.1 - 0.009 15.3 0.0 0.016 14.5 0.0 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) UIM PF02809.15 KLO10637.1 - 0.094 12.3 0.3 18 5.2 0.0 2.7 2 0 0 2 2 2 0 Ubiquitin interaction motif PGAP1 PF07819.8 KLO10637.1 - 0.15 11.6 0.0 0.35 10.4 0.0 1.5 1 0 0 1 1 1 0 PGAP1-like protein Abhydrolase_6 PF12697.2 KLO10638.1 - 6.2e-08 32.7 0.0 7.8e-08 32.4 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.8 KLO10638.1 - 7.9e-07 28.8 0.0 1.6e-06 27.8 0.0 1.5 1 0 0 1 1 1 1 PGAP1-like protein DUF676 PF05057.9 KLO10638.1 - 2.9e-05 23.4 0.0 5e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Cutinase PF01083.17 KLO10638.1 - 0.0085 15.8 0.0 0.013 15.1 0.0 1.3 1 0 0 1 1 1 1 Cutinase Abhydrolase_5 PF12695.2 KLO10638.1 - 0.02 14.6 0.0 0.031 14.0 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family KAP_NTPase PF07693.9 KLO10639.1 - 1.2e-06 27.7 0.2 1.4e-06 27.5 0.1 1.1 1 0 0 1 1 1 1 KAP family P-loop domain AAA_16 PF13191.1 KLO10639.1 - 3.8e-06 27.0 0.2 5.7e-06 26.4 0.2 1.2 1 0 0 1 1 1 1 AAA ATPase domain FAM220 PF15487.1 KLO10639.1 - 0.0011 18.4 0.0 0.0016 17.8 0.0 1.2 1 0 0 1 1 1 1 FAM220 family AAA_22 PF13401.1 KLO10639.1 - 0.0026 17.8 0.0 0.004 17.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain NACHT PF05729.7 KLO10639.1 - 0.0069 16.0 0.9 0.019 14.6 0.6 1.9 1 1 0 1 1 1 1 NACHT domain ACT PF01842.20 KLO10639.1 - 0.091 12.2 0.3 1.1 8.8 0.0 2.2 2 0 0 2 2 2 0 ACT domain APS_kinase PF01583.15 KLO10639.1 - 0.14 11.7 0.1 0.26 10.9 0.0 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase Pkinase PF00069.20 KLO10640.1 - 6.3e-11 41.9 0.1 4e-10 39.2 0.0 2.0 2 0 0 2 2 2 1 Protein kinase domain Kdo PF06293.9 KLO10640.1 - 3.9e-05 22.8 0.0 0.0013 17.8 0.0 2.2 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_Tyr PF07714.12 KLO10640.1 - 0.00027 20.0 0.0 0.00052 19.1 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 KLO10640.1 - 0.034 13.8 0.0 0.057 13.1 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family RIO1 PF01163.17 KLO10640.1 - 0.054 12.8 0.0 0.11 11.7 0.0 1.6 1 0 0 1 1 1 0 RIO1 family adh_short PF00106.20 KLO10641.1 - 5.3e-27 94.7 0.5 7.2e-27 94.3 0.3 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KLO10641.1 - 7.7e-15 55.3 0.0 1e-14 54.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KLO10641.1 - 2.8e-08 33.6 0.2 4.5e-08 32.9 0.1 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 KLO10641.1 - 0.0032 16.9 0.4 0.013 14.9 0.3 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 KLO10641.1 - 0.0054 15.6 0.3 0.0065 15.3 0.2 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein DUF1776 PF08643.5 KLO10641.1 - 0.098 11.7 0.0 0.15 11.2 0.0 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) NAD_binding_10 PF13460.1 KLO10641.1 - 0.098 12.6 0.3 0.18 11.7 0.2 1.5 1 0 0 1 1 1 0 NADH(P)-binding zf-RING_4 PF14570.1 KLO10642.1 - 5.1e-21 73.9 12.7 8.6e-21 73.2 8.8 1.4 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-C3HC4_3 PF13920.1 KLO10642.1 - 5.8e-06 25.8 9.2 9.8e-06 25.1 6.4 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) CAF-1_p150 PF11600.3 KLO10642.1 - 0.00055 19.3 41.7 0.00055 19.3 28.9 4.8 5 0 0 5 5 5 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal zf-C3HC4_2 PF13923.1 KLO10642.1 - 0.0043 17.0 12.6 0.0074 16.2 8.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-UDP PF14569.1 KLO10642.1 - 0.025 14.3 3.9 0.059 13.1 2.7 1.6 1 0 0 1 1 1 0 Zinc-binding RING-finger Baculo_IE-1 PF05290.6 KLO10642.1 - 0.079 12.6 4.3 0.15 11.7 3.0 1.3 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) RRM_1 PF00076.17 KLO10642.1 - 0.17 11.5 0.0 0.49 10.0 0.0 1.8 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-C3HC4 PF00097.20 KLO10642.1 - 0.23 11.1 12.2 0.41 10.3 8.5 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) dsDNA_bind PF01984.15 KLO10643.1 - 2.5e-26 91.7 5.7 2.9e-26 91.5 4.0 1.0 1 0 0 1 1 1 1 Double-stranded DNA-binding domain TBP PF00352.16 KLO10644.1 - 2.9e-69 228.4 0.2 1.5e-34 117.1 0.0 2.0 2 0 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) DUF3378 PF11858.3 KLO10644.1 - 0.00014 21.8 0.0 0.48 10.5 0.0 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF3378) F-box-like PF12937.2 KLO10645.1 - 0.0002 20.9 0.2 0.00047 19.8 0.1 1.6 1 0 0 1 1 1 1 F-box-like LRR_6 PF13516.1 KLO10645.1 - 3.7 7.9 7.3 0.94 9.7 0.0 3.8 6 0 0 6 6 6 0 Leucine Rich repeat DNA_pol_A PF00476.15 KLO10646.1 - 9.8e-93 310.7 0.0 1.5e-92 310.1 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase family A Cu_bind_like PF02298.12 KLO10648.1 - 0.02 14.6 3.0 0.024 14.4 0.5 2.3 2 2 0 2 2 2 0 Plastocyanin-like domain DUF2345 PF10106.4 KLO10648.1 - 0.031 13.8 5.1 0.044 13.3 3.5 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2345) MAR_sialic_bdg PF10564.4 KLO10655.1 - 0.045 13.5 0.0 0.064 13.0 0.0 1.2 1 0 0 1 1 1 0 Sialic-acid binding micronemal adhesive repeat DUF4463 PF14703.1 KLO10655.1 - 0.082 13.4 0.1 0.13 12.8 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4463) Glyco_hydro_88 PF07470.8 KLO10657.1 - 3.5e-16 59.1 0.1 4.2e-16 58.9 0.1 1.3 1 0 0 1 1 1 1 Glycosyl Hydrolase Family 88 Myco_19_kDa PF05481.7 KLO10657.1 - 0.63 9.8 5.6 0.99 9.2 2.0 2.1 2 0 0 2 2 2 0 Mycobacterium 19 kDa lipoprotein antigen Dynamin_M PF01031.15 KLO10658.1 - 2.7e-104 348.0 0.0 4.8e-104 347.2 0.0 1.4 1 0 0 1 1 1 1 Dynamin central region Dynamin_N PF00350.18 KLO10658.1 - 3e-55 186.5 0.0 5.4e-55 185.7 0.0 1.4 1 0 0 1 1 1 1 Dynamin family GED PF02212.13 KLO10658.1 - 2.1e-26 91.6 4.6 5.3e-26 90.3 3.2 1.7 1 0 0 1 1 1 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.18 KLO10658.1 - 0.00054 19.9 0.1 0.0084 16.0 0.1 2.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 KLO10658.1 - 0.048 14.1 0.0 0.15 12.5 0.0 1.8 1 0 0 1 1 1 0 Miro-like protein NTF2 PF02136.15 KLO10659.1 - 1.6e-27 96.2 0.4 1.9e-27 96.0 0.3 1.1 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain DUF4440 PF14534.1 KLO10659.1 - 0.022 14.9 0.0 0.031 14.4 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4440) MUG113 PF13455.1 KLO10661.1 - 1e-08 35.4 0.1 5.9e-07 29.8 0.0 2.6 2 0 0 2 2 2 1 Meiotically up-regulated gene 113 T5orf172 PF10544.4 KLO10661.1 - 0.00022 21.5 0.1 0.0027 18.0 0.1 2.7 1 1 0 1 1 1 1 T5orf172 domain DUF4611 PF15387.1 KLO10661.1 - 0.3 11.2 14.4 0.76 9.9 4.3 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) Daxx PF03344.10 KLO10661.1 - 2.6 6.3 18.6 3.6 5.9 12.9 1.2 1 0 0 1 1 1 0 Daxx Family DDHD PF02862.12 KLO10661.1 - 5.9 6.6 8.2 14 5.4 5.5 1.7 1 1 0 1 1 1 0 DDHD domain MUG113 PF13455.1 KLO10662.1 - 1.8e-14 53.9 0.0 5.1e-12 46.0 0.0 2.6 1 1 1 2 2 2 2 Meiotically up-regulated gene 113 T5orf172 PF10544.4 KLO10662.1 - 1.5e-10 41.3 0.0 1.6e-09 38.0 0.0 2.5 1 1 0 1 1 1 1 T5orf172 domain zf-primase PF09329.6 KLO10662.1 - 0.0087 15.6 0.7 0.019 14.5 0.1 1.8 2 0 0 2 2 2 1 Primase zinc finger DUF1180 PF06679.7 KLO10662.1 - 1.2 9.0 3.6 2.3 8.1 2.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) Cu_bind_like PF02298.12 KLO10663.1 - 0.00044 19.9 7.9 0.31 10.8 0.7 3.8 2 2 0 2 2 2 2 Plastocyanin-like domain Copper-bind PF00127.15 KLO10663.1 - 0.00081 19.5 4.0 0.26 11.5 0.1 3.6 3 2 0 3 3 3 2 Copper binding proteins, plastocyanin/azurin family Cupredoxin_1 PF13473.1 KLO10663.1 - 0.00086 19.1 1.8 1.5 8.7 0.0 2.9 3 1 0 3 3 3 2 Cupredoxin-like domain Fer2_2 PF01799.15 KLO10663.1 - 0.055 13.3 1.5 2.1 8.2 0.0 2.8 2 0 0 2 2 2 0 [2Fe-2S] binding domain zf-C3HC4 PF00097.20 KLO10664.1 - 1.7e-08 33.9 8.9 3.5e-08 32.9 6.2 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 KLO10664.1 - 6.7e-08 32.2 8.0 1.4e-07 31.2 5.5 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.1 KLO10664.1 - 3.9e-07 29.9 9.9 8e-07 28.9 6.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KLO10664.1 - 8.2e-07 28.7 8.6 2e-06 27.5 5.9 1.7 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 KLO10664.1 - 1.2e-06 28.1 6.2 2.2e-06 27.2 4.3 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KLO10664.1 - 1.7e-06 27.6 8.0 3.7e-06 26.5 5.6 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_6 PF14835.1 KLO10664.1 - 1.7e-05 24.5 2.8 3.3e-05 23.5 2.0 1.4 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-RING_UBOX PF13445.1 KLO10664.1 - 0.00017 21.2 6.9 0.00042 19.9 4.8 1.7 1 0 0 1 1 1 1 RING-type zinc-finger SAP PF02037.22 KLO10664.1 - 0.00037 19.9 0.6 0.0024 17.3 0.0 2.3 2 0 0 2 2 2 1 SAP domain U-box PF04564.10 KLO10664.1 - 0.066 13.1 0.0 0.31 11.0 0.0 2.1 2 0 0 2 2 2 0 U-box domain zf-Nse PF11789.3 KLO10664.1 - 1.1 8.8 4.9 1.2 8.6 2.0 2.0 2 0 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit Glyco_transf_15 PF01793.11 KLO10665.1 - 8.4e-140 465.4 6.5 1e-139 465.0 4.5 1.1 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase Porin_3 PF01459.17 KLO10666.1 - 7.7e-75 251.6 1.6 8.9e-75 251.4 1.1 1.0 1 0 0 1 1 1 1 Eukaryotic porin ABC_tran PF00005.22 KLO10667.1 - 1.5e-26 93.3 0.0 1.9e-26 92.9 0.0 1.1 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 KLO10667.1 - 3.1e-06 27.3 0.0 0.025 14.5 0.0 2.1 2 0 0 2 2 2 2 AAA domain NACHT PF05729.7 KLO10667.1 - 1.2e-05 25.0 0.2 0.0015 18.2 0.1 2.2 2 0 0 2 2 2 1 NACHT domain AAA_22 PF13401.1 KLO10667.1 - 5.8e-05 23.2 0.0 9.9e-05 22.4 0.0 1.5 1 1 0 1 1 1 1 AAA domain SbcCD_C PF13558.1 KLO10667.1 - 7.1e-05 22.6 0.1 0.00024 20.9 0.1 1.9 1 1 0 1 1 1 1 Putative exonuclease SbcCD, C subunit DUF258 PF03193.11 KLO10667.1 - 7.6e-05 21.9 0.0 0.00013 21.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_29 PF13555.1 KLO10667.1 - 0.00012 21.5 0.0 0.00021 20.7 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain SMC_N PF02463.14 KLO10667.1 - 0.00013 21.3 0.0 0.014 14.5 0.0 2.1 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.1 KLO10667.1 - 0.001 19.0 0.1 0.0025 17.8 0.0 1.6 2 0 0 2 2 2 1 AAA ATPase domain AAA_25 PF13481.1 KLO10667.1 - 0.0017 17.7 0.0 0.004 16.5 0.0 1.6 2 0 0 2 2 2 1 AAA domain DUF815 PF05673.8 KLO10667.1 - 0.0033 16.3 0.1 0.14 11.0 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF815) UPF0079 PF02367.12 KLO10667.1 - 0.0044 16.6 0.0 0.0073 15.9 0.0 1.3 1 0 0 1 1 1 1 Uncharacterised P-loop hydrolase UPF0079 AAA_15 PF13175.1 KLO10667.1 - 0.0047 16.0 0.0 0.032 13.2 0.0 1.9 1 1 0 2 2 2 1 AAA ATPase domain AAA_17 PF13207.1 KLO10667.1 - 0.0066 17.2 0.1 0.019 15.8 0.1 2.1 1 1 0 1 1 1 1 AAA domain AAA_23 PF13476.1 KLO10667.1 - 0.0079 16.5 0.0 0.0092 16.3 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.9 KLO10667.1 - 0.011 15.5 0.1 0.044 13.5 0.1 1.9 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_19 PF13245.1 KLO10667.1 - 0.011 15.4 0.0 0.022 14.4 0.0 1.5 1 0 0 1 1 1 0 Part of AAA domain AAA_30 PF13604.1 KLO10667.1 - 0.014 14.9 0.0 0.075 12.6 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.1 KLO10667.1 - 0.02 15.2 0.3 0.044 14.0 0.2 1.8 1 1 0 1 1 1 0 AAA domain Rad17 PF03215.10 KLO10667.1 - 0.027 13.1 0.0 0.038 12.6 0.0 1.1 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein MMR_HSR1 PF01926.18 KLO10667.1 - 0.035 14.0 0.0 0.065 13.1 0.0 1.5 1 1 0 1 1 1 0 50S ribosome-binding GTPase VirE PF05272.6 KLO10667.1 - 0.039 13.4 0.0 0.064 12.7 0.0 1.3 1 0 0 1 1 1 0 Virulence-associated protein E AAA_33 PF13671.1 KLO10667.1 - 0.048 13.5 0.1 0.075 12.9 0.1 1.6 1 1 0 1 1 1 0 AAA domain Viral_helicase1 PF01443.13 KLO10667.1 - 0.053 13.0 0.1 0.11 11.9 0.1 1.5 2 0 0 2 2 1 0 Viral (Superfamily 1) RNA helicase AAA_14 PF13173.1 KLO10667.1 - 0.073 12.9 0.1 0.16 11.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_10 PF12846.2 KLO10667.1 - 0.093 12.1 0.0 0.12 11.8 0.0 1.2 1 0 0 1 1 1 0 AAA-like domain PduV-EutP PF10662.4 KLO10667.1 - 0.093 12.2 0.1 0.18 11.2 0.1 1.4 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation RNA_helicase PF00910.17 KLO10667.1 - 0.1 12.7 0.1 0.19 11.9 0.0 1.4 1 0 0 1 1 1 0 RNA helicase AAA PF00004.24 KLO10667.1 - 0.11 12.6 0.2 0.38 10.9 0.1 2.0 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) ABC_ATPase PF09818.4 KLO10667.1 - 0.11 11.0 0.1 7 5.1 0.0 2.1 2 0 0 2 2 2 0 Predicted ATPase of the ABC class PI3_PI4_kinase PF00454.22 KLO10668.1 - 1.9e-37 128.9 0.0 3.3e-37 128.2 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase Pik1 PF11522.3 KLO10668.1 - 0.0061 16.2 0.0 0.014 15.1 0.0 1.6 1 0 0 1 1 1 1 Yeast phosphatidylinositol-4-OH kinase Pik1 TRAPPC9-Trs120 PF08626.6 KLO10669.1 - 1.6e-112 376.8 0.0 2.7e-80 270.1 0.0 2.3 1 1 1 2 2 2 2 Transport protein Trs120 or TRAPPC9, TRAPP II complex subunit TPR_11 PF13414.1 KLO10669.1 - 0.12 12.0 0.1 0.29 10.7 0.0 1.7 1 0 0 1 1 1 0 TPR repeat TPR_12 PF13424.1 KLO10669.1 - 0.12 12.2 0.0 0.39 10.6 0.0 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat Vps55 PF04133.9 KLO10670.1 - 3.5e-42 142.9 3.2 4e-42 142.7 2.2 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting 55 BCLP PF12304.3 KLO10670.1 - 0.0084 15.5 1.6 0.02 14.3 0.5 1.8 1 1 1 2 2 2 1 Beta-casein like protein FA_desaturase PF00487.19 KLO10670.1 - 0.17 11.2 1.5 0.24 10.8 1.0 1.2 1 0 0 1 1 1 0 Fatty acid desaturase Elf1 PF05129.8 KLO10671.1 - 1.1e-22 79.4 0.5 1.3e-22 79.3 0.3 1.0 1 0 0 1 1 1 1 Transcription elongation factor Elf1 like DUF177 PF02620.12 KLO10671.1 - 0.052 13.5 0.0 0.091 12.8 0.0 1.5 2 0 0 2 2 2 0 Uncharacterized ACR, COG1399 zf-CSL PF05207.8 KLO10671.1 - 0.074 12.5 0.0 0.1 12.1 0.0 1.2 1 0 0 1 1 1 0 CSL zinc finger zf-dskA_traR PF01258.12 KLO10671.1 - 0.38 10.5 1.7 1.2 8.8 0.1 2.1 2 0 0 2 2 2 0 Prokaryotic dksA/traR C4-type zinc finger Kinesin PF00225.18 KLO10672.1 - 1.8e-107 358.9 0.5 3.8e-107 357.8 0.0 1.9 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bind PF13931.1 KLO10672.1 - 6.5e-07 29.5 1.9 6.5e-07 29.5 1.3 5.2 4 1 1 5 5 5 1 Kinesin-associated microtubule-binding Phage_Mu_Gam PF07352.7 KLO10672.1 - 0.015 14.8 0.3 0.015 14.8 0.2 4.1 3 1 0 3 3 3 0 Bacteriophage Mu Gam like protein Kinesin PF00225.18 KLO10673.1 - 1.1e-111 372.8 0.1 1.1e-111 372.8 0.0 2.5 3 0 0 3 3 3 1 Kinesin motor domain DASH_Dam1 PF08653.5 KLO10673.1 - 2 8.2 6.7 13 5.5 0.1 4.9 3 1 1 4 4 4 0 DASH complex subunit Dam1 PUF PF00806.14 KLO10675.1 - 1.3e-59 194.4 4.9 2.2e-08 33.1 0.0 8.4 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat EH_Signature PF15611.1 KLO10675.1 - 0.005 15.9 0.0 0.37 9.7 0.0 2.1 1 1 1 2 2 2 2 EH_Signature domain DUF3683 PF12447.3 KLO10675.1 - 0.07 12.9 0.7 0.41 10.4 0.1 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3683) Sec16_C PF12931.2 KLO10677.1 - 7.4e-67 226.0 0.0 1.2e-66 225.4 0.0 1.3 1 0 0 1 1 1 1 Sec23-binding domain of Sec16 Sec16 PF12932.2 KLO10677.1 - 1.4e-27 95.9 0.5 1.3e-26 92.9 0.0 2.3 2 0 0 2 2 2 1 Vesicle coat trafficking protein Sec16 mid-region OST3_OST6 PF04756.8 KLO10678.1 - 7.4e-11 41.8 7.0 1.1e-10 41.2 4.8 1.2 1 0 0 1 1 1 1 OST3 / OST6 family Thioredoxin PF00085.15 KLO10678.1 - 0.0004 20.0 0.0 0.00065 19.3 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin C1_1 PF00130.17 KLO10679.1 - 2.5e-07 30.3 12.7 8.3e-07 28.6 0.4 2.5 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) UNC-79 PF14776.1 KLO10679.1 - 0.016 13.6 0.0 0.027 12.8 0.0 1.2 1 0 0 1 1 1 0 Cation-channel complex subunit UNC-79 DZR PF12773.2 KLO10679.1 - 3.4 7.5 6.4 11 5.9 0.2 2.4 2 0 0 2 2 2 0 Double zinc ribbon PHD PF00628.24 KLO10679.1 - 5.6 6.7 15.4 2.4 7.9 0.7 2.4 2 0 0 2 2 2 0 PHD-finger HMD PF03201.11 KLO10680.1 - 0.15 12.0 0.0 0.23 11.4 0.0 1.3 1 0 0 1 1 1 0 H2-forming N5,N10-methylene-tetrahydromethanopterin dehydrogenase Pkinase PF00069.20 KLO10681.1 - 4.9e-11 42.2 0.2 3.9e-10 39.3 0.0 2.2 2 0 0 2 2 2 1 Protein kinase domain Kdo PF06293.9 KLO10681.1 - 0.00014 21.0 0.1 0.00039 19.5 0.1 1.7 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_Tyr PF07714.12 KLO10681.1 - 0.00077 18.5 0.0 0.0017 17.5 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Choline_kinase PF01633.15 KLO10681.1 - 0.011 15.2 0.1 0.026 14.1 0.0 1.6 2 0 0 2 2 2 0 Choline/ethanolamine kinase APH PF01636.18 KLO10681.1 - 0.068 12.8 0.1 0.17 11.6 0.0 1.6 2 0 0 2 2 2 0 Phosphotransferase enzyme family RIO1 PF01163.17 KLO10681.1 - 0.1 11.9 0.0 0.28 10.4 0.0 1.7 1 0 0 1 1 1 0 RIO1 family Pkinase PF00069.20 KLO10682.1 - 0.0099 15.0 0.0 0.013 14.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.9 KLO10682.1 - 0.046 12.7 0.1 0.12 11.4 0.0 1.6 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Cbl_N2 PF02761.9 KLO10682.1 - 0.071 13.1 0.0 0.23 11.5 0.0 1.8 1 0 0 1 1 1 0 CBL proto-oncogene N-terminus, EF hand-like domain Pkinase PF00069.20 KLO10683.1 - 4.9e-05 22.6 0.0 6.8e-05 22.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.9 KLO10683.1 - 0.0001 21.4 0.0 0.00017 20.7 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KLO10683.1 - 0.0011 18.7 0.0 0.0016 18.2 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_Tyr PF07714.12 KLO10683.1 - 0.0062 15.6 0.0 0.01 14.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase NOC3p PF07540.6 KLO10684.1 - 2.8e-27 94.8 0.0 8.4e-27 93.2 0.0 1.9 1 0 0 1 1 1 1 Nucleolar complex-associated protein CBF PF03914.12 KLO10684.1 - 5.9e-24 84.3 0.5 9.8e-22 77.1 0.0 3.2 2 1 1 3 3 3 2 CBF/Mak21 family Apc5 PF12862.2 KLO10685.1 - 7.4e-10 38.5 0.3 4.8e-09 35.9 0.1 2.3 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 5 TPR_14 PF13428.1 KLO10685.1 - 0.011 16.3 0.2 0.96 10.2 0.0 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat Methyltransf_3 PF01596.12 KLO10686.1 - 2.8e-39 134.3 0.2 3e-39 134.2 0.1 1.0 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_24 PF13578.1 KLO10686.1 - 5.9e-16 59.2 0.0 8.2e-16 58.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KLO10686.1 - 3.9e-13 49.2 0.0 4.7e-13 48.9 0.0 1.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KLO10686.1 - 4.1e-10 40.2 0.0 5.7e-10 39.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.10 KLO10686.1 - 1.7e-06 27.5 0.0 2.3e-06 27.1 0.0 1.1 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_26 PF13659.1 KLO10686.1 - 2.9e-06 27.3 0.0 4e-06 26.8 0.0 1.3 1 1 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 KLO10686.1 - 3.3e-06 26.7 0.0 4.3e-06 26.4 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) CMAS PF02353.15 KLO10686.1 - 0.00011 21.3 0.0 0.00015 20.9 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_11 PF08241.7 KLO10686.1 - 0.00016 22.1 0.0 0.00054 20.4 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KLO10686.1 - 0.00059 20.1 0.0 0.00089 19.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain CmcI PF04989.7 KLO10686.1 - 0.0025 17.1 0.0 0.0034 16.7 0.0 1.1 1 0 0 1 1 1 1 Cephalosporin hydroxylase Methyltransf_15 PF09445.5 KLO10686.1 - 0.0068 15.9 0.0 0.0095 15.4 0.0 1.2 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Ubie_methyltran PF01209.13 KLO10686.1 - 0.023 13.8 0.0 0.034 13.2 0.0 1.3 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family UPF0020 PF01170.13 KLO10686.1 - 0.12 11.9 0.0 0.16 11.5 0.0 1.2 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 DSBA PF01323.15 KLO10687.1 - 0.021 14.4 0.1 0.033 13.7 0.1 1.4 1 1 0 1 1 1 0 DSBA-like thioredoxin domain TPR_12 PF13424.1 KLO10688.1 - 1.3e-16 60.3 18.2 0.0014 18.4 0.5 6.9 5 1 3 8 8 8 6 Tetratricopeptide repeat TPR_2 PF07719.12 KLO10688.1 - 1.5e-10 40.1 10.9 0.53 10.3 0.1 8.0 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_11 PF13414.1 KLO10688.1 - 5.6e-10 38.7 9.3 0.017 14.7 0.4 5.8 5 0 0 5 5 5 3 TPR repeat AAA_22 PF13401.1 KLO10688.1 - 8.9e-09 35.5 2.3 6e-07 29.6 0.0 4.1 3 1 1 4 4 4 1 AAA domain NB-ARC PF00931.17 KLO10688.1 - 5.5e-08 32.0 0.0 1.1e-07 31.0 0.0 1.4 1 0 0 1 1 1 1 NB-ARC domain TPR_7 PF13176.1 KLO10688.1 - 7.4e-07 28.5 15.5 0.3 10.9 0.7 6.7 7 0 0 7 7 7 3 Tetratricopeptide repeat NACHT PF05729.7 KLO10688.1 - 4.3e-06 26.4 0.5 2.1e-05 24.2 0.0 2.3 2 0 0 2 2 2 1 NACHT domain TPR_1 PF00515.23 KLO10688.1 - 5.7e-05 22.5 12.0 0.64 9.7 0.2 7.2 7 0 0 7 7 7 1 Tetratricopeptide repeat Arch_ATPase PF01637.13 KLO10688.1 - 0.00015 21.5 0.0 0.00034 20.3 0.0 1.6 1 0 0 1 1 1 1 Archaeal ATPase SNAP PF14938.1 KLO10688.1 - 0.0077 15.4 4.0 0.029 13.5 0.1 3.1 3 1 0 3 3 3 1 Soluble NSF attachment protein, SNAP Apc3 PF12895.2 KLO10688.1 - 0.0088 16.1 6.5 7 6.8 0.7 4.8 3 1 2 5 5 5 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_10 PF13374.1 KLO10688.1 - 0.052 13.4 26.8 1.2 9.1 1.0 8.0 9 0 0 9 9 7 0 Tetratricopeptide repeat AAA PF00004.24 KLO10688.1 - 0.069 13.3 0.0 0.26 11.4 0.0 2.0 2 0 0 2 2 1 0 ATPase family associated with various cellular activities (AAA) TPR_8 PF13181.1 KLO10688.1 - 0.1 12.4 4.7 70 3.5 0.0 5.5 6 0 0 6 6 6 0 Tetratricopeptide repeat AAA_16 PF13191.1 KLO10688.1 - 0.17 11.8 0.1 0.17 11.8 0.0 3.7 3 1 1 4 4 4 0 AAA ATPase domain TPR_16 PF13432.1 KLO10688.1 - 0.24 12.1 0.0 0.24 12.1 0.0 6.1 6 2 0 6 6 5 0 Tetratricopeptide repeat Apc5 PF12862.2 KLO10688.1 - 2.2 8.1 6.3 7.8 6.4 0.3 4.0 4 1 1 5 5 5 0 Anaphase-promoting complex subunit 5 FliO PF04347.8 KLO10690.1 - 0.0026 17.7 0.1 0.012 15.6 0.0 2.0 1 1 1 2 2 2 1 Flagellar biosynthesis protein, FliO zf-C3HC4_3 PF13920.1 KLO10690.1 - 1.8 8.2 8.4 3.1 7.5 5.9 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) E1-E2_ATPase PF00122.15 KLO10691.1 - 4.4e-65 218.9 7.1 4.4e-65 218.9 4.9 2.7 3 1 1 4 4 4 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 KLO10691.1 - 1e-44 152.2 8.5 1e-44 152.2 5.9 2.1 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 KLO10691.1 - 2.3e-33 116.4 0.0 3.3e-32 112.6 0.0 2.6 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 KLO10691.1 - 1.3e-22 78.9 0.4 5.6e-22 76.9 0.0 2.2 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_like2 PF13246.1 KLO10691.1 - 7.5e-22 77.1 0.0 1.5e-21 76.1 0.0 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 KLO10691.1 - 2.9e-15 56.9 0.0 7.3e-15 55.6 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 KLO10691.1 - 1.3e-07 31.4 1.5 5.3e-06 26.2 1.0 2.4 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 KLO10691.1 - 0.0028 17.8 0.0 0.0059 16.8 0.0 1.5 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase DPBB_1 PF03330.13 KLO10692.1 - 6.8e-08 32.4 0.0 8.8e-08 32.0 0.0 1.3 1 1 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Barwin PF00967.12 KLO10692.1 - 0.067 12.8 0.0 0.081 12.6 0.0 1.2 1 0 0 1 1 1 0 Barwin family RRM_1 PF00076.17 KLO10693.1 - 2.8e-26 90.9 0.0 3.8e-13 48.8 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PUF PF00806.14 KLO10693.1 - 6.7e-23 78.8 0.0 3.5e-05 23.0 0.0 5.9 5 0 0 5 5 5 5 Pumilio-family RNA binding repeat RRM_6 PF14259.1 KLO10693.1 - 1.5e-18 66.5 0.0 8.4e-09 35.2 0.0 2.8 3 0 0 3 3 3 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KLO10693.1 - 1.7e-13 50.2 0.0 9.3e-07 28.6 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SHOCT PF09851.4 KLO10693.1 - 0.27 10.7 0.3 0.49 9.9 0.2 1.4 1 0 0 1 1 1 0 Short C-terminal domain Nab6_mRNP_bdg PF10567.4 KLO10693.1 - 0.51 9.2 0.0 1.1 8.1 0.0 1.5 1 0 0 1 1 1 0 RNA-recognition motif DUF1212 PF06738.7 KLO10694.1 - 7.2e-34 116.9 12.3 6.6e-33 113.7 0.8 3.0 3 0 0 3 3 3 2 Protein of unknown function (DUF1212) DUF3815 PF12821.2 KLO10694.1 - 3.7e-17 62.4 21.6 2.3e-15 56.6 3.1 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF3815) Pkinase PF00069.20 KLO10695.1 - 1e-09 37.9 0.1 9.9e-09 34.7 0.0 2.2 2 0 0 2 2 2 1 Protein kinase domain Kdo PF06293.9 KLO10695.1 - 0.00017 20.7 0.0 0.00031 19.8 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_Tyr PF07714.12 KLO10695.1 - 0.0012 18.0 0.0 0.0021 17.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.17 KLO10695.1 - 0.025 13.9 0.0 0.078 12.3 0.0 1.8 1 0 0 1 1 1 0 RIO1 family Pkinase PF00069.20 KLO10696.1 - 8.7e-08 31.6 0.0 1.1e-07 31.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.9 KLO10696.1 - 0.0011 18.0 0.0 0.0017 17.4 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_Tyr PF07714.12 KLO10696.1 - 0.0013 17.9 0.0 0.0017 17.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 KLO10697.1 - 8.7e-11 41.4 0.0 1.5e-10 40.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KLO10697.1 - 0.00035 19.7 0.0 0.00057 19.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 KLO10697.1 - 0.0022 17.1 0.0 0.0038 16.3 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family CBP4 PF07960.6 KLO10698.1 - 7.2e-06 25.6 2.1 2.2e-05 24.0 1.5 1.7 1 1 0 1 1 1 1 CBP4 DUF3619 PF12279.3 KLO10698.1 - 0.022 14.8 1.3 0.022 14.8 0.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3619) CCDC144C PF14915.1 KLO10698.1 - 0.028 13.3 0.1 0.03 13.2 0.1 1.0 1 0 0 1 1 1 0 CCDC144C protein coiled-coil region Troponin PF00992.15 KLO10698.1 - 0.043 13.8 0.1 0.047 13.7 0.1 1.0 1 0 0 1 1 1 0 Troponin Nuc_sug_transp PF04142.10 KLO10699.1 - 4.6e-08 32.4 0.7 9e-08 31.5 0.5 1.4 1 0 0 1 1 1 1 Nucleotide-sugar transporter EamA PF00892.15 KLO10699.1 - 1.8e-05 24.7 26.9 0.00037 20.5 3.9 3.7 2 1 0 2 2 2 2 EamA-like transporter family UAA PF08449.6 KLO10699.1 - 4.7e-05 22.4 7.9 7.2e-05 21.8 5.5 1.2 1 0 0 1 1 1 1 UAA transporter family TPT PF03151.11 KLO10699.1 - 0.022 14.4 0.6 0.022 14.4 0.4 3.3 2 1 0 2 2 2 0 Triose-phosphate Transporter family DUF3353 PF11833.3 KLO10699.1 - 1.3 8.4 4.9 0.19 11.2 0.4 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3353) ATP-synt_8 PF00895.15 KLO10701.1 - 0.22 11.7 1.6 0.48 10.6 1.1 1.7 1 0 0 1 1 1 0 ATP synthase protein 8 Ndc1_Nup PF09531.5 KLO10701.1 - 1.7 6.9 5.8 2 6.7 4.0 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DPBB_1 PF03330.13 KLO10703.1 - 1.9e-05 24.5 0.0 5.3e-05 23.1 0.0 1.9 2 0 0 2 2 2 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel DUF2217 PF10265.4 KLO10703.1 - 0.31 9.7 4.2 0.44 9.2 2.9 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) FliD_N PF02465.13 KLO10703.1 - 2.5 8.5 11.2 83 3.6 8.3 2.2 2 0 0 2 2 2 0 Flagellar hook-associated protein 2 N-terminus DUF605 PF04652.11 KLO10703.1 - 6.2 6.1 16.7 8.2 5.7 11.6 1.1 1 0 0 1 1 1 0 Vta1 like F-box-like PF12937.2 KLO10704.1 - 7.7e-05 22.3 0.4 0.00033 20.3 0.1 2.1 2 0 0 2 2 2 1 F-box-like Spc24 PF08286.6 KLO10706.1 - 7.6e-10 38.5 0.0 3.1e-09 36.5 0.0 1.8 2 0 0 2 2 2 1 Spc24 subunit of Ndc80 Cauli_DNA-bind PF03310.8 KLO10706.1 - 0.087 12.6 0.1 0.18 11.6 0.1 1.5 1 1 0 1 1 1 0 Caulimovirus DNA-binding protein CAF1A PF12253.3 KLO10707.1 - 2.6e-21 75.5 2.4 2.6e-21 75.5 1.7 2.1 2 0 0 2 2 2 1 Chromatin assembly factor 1 subunit A TUSC2 PF15000.1 KLO10707.1 - 0.024 14.6 0.2 0.21 11.6 0.0 2.6 2 0 0 2 2 2 0 Tumour suppressor candidate 2 AAA PF00004.24 KLO10708.1 - 6.1e-15 55.5 0.0 1.3e-14 54.4 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.1 KLO10708.1 - 3.6e-13 49.5 0.0 2.1e-12 47.0 0.0 2.1 1 1 0 1 1 1 1 DNA polymerase III, delta subunit Rep_fac_C PF08542.6 KLO10708.1 - 9.6e-10 38.3 0.0 2.5e-09 37.0 0.0 1.6 1 0 0 1 1 1 1 Replication factor C C-terminal domain Rad17 PF03215.10 KLO10708.1 - 3.7e-09 35.8 0.0 1.8e-06 26.9 0.0 2.2 1 1 1 2 2 2 2 Rad17 cell cycle checkpoint protein AAA_22 PF13401.1 KLO10708.1 - 1.1e-07 32.0 0.0 2.7e-07 30.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 KLO10708.1 - 2.4e-05 24.4 0.0 0.00018 21.5 0.0 2.1 1 1 0 1 1 1 1 AAA ATPase domain RuvB_N PF05496.7 KLO10708.1 - 3.2e-05 23.0 0.0 6.6e-05 22.0 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_11 PF13086.1 KLO10708.1 - 4.9e-05 23.0 0.0 6.9e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 KLO10708.1 - 6.2e-05 22.6 0.0 0.00028 20.5 0.0 2.0 2 0 0 2 2 2 1 Part of AAA domain AAA_14 PF13173.1 KLO10708.1 - 0.00015 21.6 0.0 0.00029 20.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.1 KLO10708.1 - 0.00041 20.0 0.0 0.0009 18.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.9 KLO10708.1 - 0.00085 19.0 0.0 0.0032 17.1 0.0 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.16 KLO10708.1 - 0.0023 17.1 0.0 0.071 12.2 0.0 2.2 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_30 PF13604.1 KLO10708.1 - 0.0026 17.3 0.0 0.0055 16.3 0.0 1.5 1 1 0 1 1 1 1 AAA domain DUF2075 PF09848.4 KLO10708.1 - 0.0027 16.7 0.0 0.0043 16.0 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_10 PF12846.2 KLO10708.1 - 0.0086 15.5 0.1 0.46 9.8 0.0 2.3 1 1 0 2 2 2 1 AAA-like domain AAA_17 PF13207.1 KLO10708.1 - 0.017 15.8 0.0 0.035 14.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.1 KLO10708.1 - 0.02 15.1 0.0 0.032 14.5 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.1 KLO10708.1 - 0.024 14.0 0.0 0.063 12.6 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA_2 PF07724.9 KLO10708.1 - 0.024 14.5 0.0 0.047 13.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) DUF815 PF05673.8 KLO10708.1 - 0.03 13.2 0.0 0.05 12.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) SNF2_N PF00176.18 KLO10708.1 - 0.031 13.0 0.0 1.1 8.0 0.0 2.1 1 1 0 2 2 2 0 SNF2 family N-terminal domain DNA_pol3_delta PF06144.8 KLO10708.1 - 0.031 13.7 0.0 0.064 12.7 0.0 1.4 1 0 0 1 1 1 0 DNA polymerase III, delta subunit DEAD PF00270.24 KLO10708.1 - 0.036 13.5 0.1 0.34 10.4 0.0 2.1 1 1 0 2 2 2 0 DEAD/DEAH box helicase FtsK_SpoIIIE PF01580.13 KLO10708.1 - 0.038 13.4 0.3 0.78 9.1 0.0 2.2 1 1 1 2 2 2 0 FtsK/SpoIIIE family AAA_28 PF13521.1 KLO10708.1 - 0.076 12.9 0.0 0.12 12.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain Sec3_C_2 PF15278.1 KLO10708.1 - 0.09 12.9 0.1 0.41 10.8 0.0 2.1 2 0 0 2 2 2 0 Sec3 exocyst complex subunit AAA_18 PF13238.1 KLO10708.1 - 0.1 12.9 0.0 0.2 11.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain ResIII PF04851.10 KLO10708.1 - 0.13 12.0 0.0 0.42 10.4 0.0 1.7 1 1 1 2 2 2 0 Type III restriction enzyme, res subunit HSP70 PF00012.15 KLO10709.1 - 4e-240 797.8 10.4 5e-240 797.5 7.2 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 KLO10709.1 - 3.6e-18 65.2 0.4 3.8e-17 61.8 0.2 2.2 2 0 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.11 KLO10709.1 - 0.0038 16.8 0.0 0.0088 15.6 0.0 1.6 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain BcrAD_BadFG PF01869.15 KLO10709.1 - 0.0079 15.5 0.7 0.3 10.3 0.0 2.9 3 0 0 3 3 3 1 BadF/BadG/BcrA/BcrD ATPase family StbA PF06406.6 KLO10709.1 - 0.023 13.6 0.0 0.17 10.7 0.0 2.3 2 1 0 2 2 2 0 StbA protein Ribosomal_S2 PF00318.15 KLO10710.1 - 8.7e-46 155.7 0.0 6.1e-43 146.4 0.0 2.1 1 1 0 1 1 1 1 Ribosomal protein S2 2OG-FeII_Oxy_3 PF13640.1 KLO10713.1 - 3.2e-05 24.3 0.1 4.8e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.15 KLO10713.1 - 0.0042 17.3 0.1 0.0067 16.7 0.1 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_3 PF13640.1 KLO10714.1 - 1.6e-06 28.5 0.1 3.1e-05 24.3 0.0 2.6 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.15 KLO10714.1 - 0.011 16.0 0.0 0.022 15.0 0.0 1.5 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily Chorismate_bind PF00425.13 KLO10715.1 - 1.4e-87 293.2 0.0 2.1e-87 292.6 0.0 1.3 1 0 0 1 1 1 1 chorismate binding enzyme Anth_synt_I_N PF04715.8 KLO10715.1 - 3.1e-27 95.3 0.0 4.3e-26 91.5 0.0 2.5 2 0 0 2 2 2 1 Anthranilate synthase component I, N terminal region Peptidase_C74 PF12387.3 KLO10715.1 - 0.039 13.1 0.0 0.063 12.4 0.0 1.2 1 0 0 1 1 1 0 Pestivirus NS2 peptidase SHQ1 PF04925.10 KLO10716.1 - 1.8e-52 177.5 0.0 4.6e-52 176.2 0.0 1.6 2 0 0 2 2 2 1 SHQ1 protein PIH1 PF08190.7 KLO10716.1 - 0.00016 21.2 1.9 0.00045 19.7 0.0 2.3 3 0 0 3 3 3 1 pre-RNA processing PIH1/Nop17 CS PF04969.11 KLO10716.1 - 0.00061 20.2 0.0 0.0012 19.3 0.0 1.5 1 0 0 1 1 1 1 CS domain Pkinase PF00069.20 KLO10717.1 - 4.3e-06 26.0 0.3 6e-05 22.3 0.0 2.2 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 KLO10717.1 - 0.036 13.1 0.0 0.069 12.2 0.0 1.4 1 0 0 1 1 1 0 Protein tyrosine kinase Kdo PF06293.9 KLO10717.1 - 0.13 11.3 0.0 0.27 10.2 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF702 PF05142.7 KLO10718.1 - 0.72 10.0 10.6 0.084 13.0 3.7 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF702) adh_short PF00106.20 KLO10723.1 - 1e-09 38.5 1.0 2.2e-09 37.4 0.5 1.7 2 1 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.1 KLO10723.1 - 2.2e-07 30.9 0.1 2.7e-07 30.5 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KLO10723.1 - 0.0033 17.1 0.1 0.0063 16.1 0.1 1.5 1 0 0 1 1 1 1 KR domain Aldo_ket_red PF00248.16 KLO10724.1 - 2.7e-67 226.5 0.0 3.6e-67 226.1 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Saccharop_dh PF03435.13 KLO10724.1 - 0.055 12.4 0.0 0.63 8.9 0.0 1.9 1 1 0 2 2 2 0 Saccharopine dehydrogenase Aldo_ket_red PF00248.16 KLO10725.1 - 1e-69 234.5 0.0 1.2e-69 234.2 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family PQ-loop PF04193.9 KLO10726.1 - 2.8e-39 132.4 7.0 3.7e-20 71.2 0.5 2.4 2 0 0 2 2 2 2 PQ loop repeat MtN3_slv PF03083.11 KLO10726.1 - 0.053 13.3 0.5 0.053 13.3 0.4 2.0 2 0 0 2 2 2 0 Sugar efflux transporter for intercellular exchange p450 PF00067.17 KLO10727.1 - 8.1e-70 235.6 0.0 1e-69 235.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Nuc_sug_transp PF04142.10 KLO10728.1 - 2.8e-76 255.8 5.7 4.2e-76 255.2 4.0 1.2 1 0 0 1 1 1 1 Nucleotide-sugar transporter UAA PF08449.6 KLO10728.1 - 1.6e-08 33.8 5.2 2.4e-08 33.2 3.6 1.2 1 0 0 1 1 1 1 UAA transporter family EmrE PF13536.1 KLO10728.1 - 8.4e-08 32.4 0.6 8.4e-08 32.4 0.4 2.6 2 0 0 2 2 2 1 Multidrug resistance efflux transporter TPT PF03151.11 KLO10728.1 - 0.00029 20.5 19.2 0.00049 19.7 0.2 2.7 2 1 0 2 2 2 1 Triose-phosphate Transporter family EamA PF00892.15 KLO10728.1 - 0.00036 20.5 17.9 0.00097 19.1 0.4 2.6 2 0 0 2 2 2 2 EamA-like transporter family HhH-GPD PF00730.20 KLO10729.1 - 9.6e-19 67.6 0.0 2.4e-18 66.3 0.0 1.7 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein NUDIX_4 PF14815.1 KLO10729.1 - 5e-12 45.2 0.0 1.2e-09 37.5 0.0 2.5 1 1 1 2 2 2 2 NUDIX domain HHH PF00633.18 KLO10729.1 - 0.0011 18.5 0.1 0.0056 16.3 0.0 2.3 2 0 0 2 2 2 1 Helix-hairpin-helix motif EndIII_4Fe-2S PF10576.4 KLO10729.1 - 1.9 8.7 11.3 0.07 13.3 3.4 2.1 2 0 0 2 2 2 0 Iron-sulfur binding domain of endonuclease III Aldo_ket_red PF00248.16 KLO10730.1 - 6.2e-68 228.6 0.0 7.9e-68 228.3 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Saccharop_dh PF03435.13 KLO10730.1 - 0.027 13.4 0.0 0.49 9.3 0.0 2.0 1 1 0 2 2 2 0 Saccharopine dehydrogenase adh_short PF00106.20 KLO10731.1 - 2.5e-10 40.5 0.2 4.5e-10 39.6 0.1 1.5 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KLO10731.1 - 2e-08 34.3 0.0 2.5e-08 33.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KLO10731.1 - 0.003 17.2 0.1 0.0046 16.6 0.0 1.3 1 0 0 1 1 1 1 KR domain NmrA PF05368.8 KLO10731.1 - 0.031 13.5 0.4 0.055 12.7 0.3 1.3 1 0 0 1 1 1 0 NmrA-like family adh_short_C2 PF13561.1 KLO10732.1 - 1.2e-08 35.0 0.0 1.5e-08 34.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 KLO10732.1 - 2.5e-06 27.5 1.7 5.2e-06 26.4 1.2 1.6 1 1 0 1 1 1 1 short chain dehydrogenase adh_short PF00106.20 KLO10733.1 - 1e-13 51.5 0.2 1.6e-13 50.8 0.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KLO10733.1 - 3.9e-09 36.6 0.1 5.5e-09 36.1 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 KLO10733.1 - 0.00023 20.6 0.3 0.0026 17.2 0.2 2.1 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.5 KLO10733.1 - 0.00035 20.2 0.0 0.00058 19.5 0.0 1.3 1 0 0 1 1 1 1 KR domain NmrA PF05368.8 KLO10733.1 - 0.0032 16.7 0.2 0.0058 15.9 0.2 1.3 1 0 0 1 1 1 1 NmrA-like family APG17 PF04108.7 KLO10733.1 - 0.012 14.4 0.1 2.3 6.9 0.1 2.1 2 0 0 2 2 2 0 Autophagy protein Apg17 NAD_binding_4 PF07993.7 KLO10733.1 - 0.021 13.7 0.1 0.45 9.3 0.0 2.2 2 0 0 2 2 2 0 Male sterility protein DUF3493 PF11998.3 KLO10733.1 - 0.1 12.4 0.2 0.22 11.4 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3493) DHDPS PF00701.17 KLO10734.1 - 1.4e-30 105.8 0.0 6e-30 103.8 0.0 1.7 1 1 0 1 1 1 1 Dihydrodipicolinate synthetase family TruB_N PF01509.13 KLO10736.1 - 7.6e-44 149.4 0.0 1.8e-43 148.2 0.0 1.6 2 0 0 2 2 2 1 TruB family pseudouridylate synthase (N terminal domain) Aldo_ket_red PF00248.16 KLO10737.1 - 7.8e-64 215.2 0.0 9.8e-64 214.8 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family NAD_binding_6 PF08030.7 KLO10739.1 - 4.6e-16 59.1 0.1 9.9e-16 58.0 0.0 1.6 1 1 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.7 KLO10739.1 - 1.4e-11 44.1 0.0 6.5e-11 42.0 0.0 2.1 1 1 0 1 1 1 1 FAD-binding domain Ferric_reduct PF01794.14 KLO10739.1 - 8.7e-10 38.7 8.2 8.7e-10 38.7 5.7 2.4 3 1 0 3 3 3 1 Ferric reductase like transmembrane component Epimerase PF01370.16 KLO10740.1 - 3.6e-21 75.6 0.1 7.9e-21 74.5 0.1 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 KLO10740.1 - 2.8e-16 60.0 0.8 1.2e-15 57.9 0.5 2.1 1 1 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 KLO10740.1 - 1e-15 57.2 0.2 8.9e-15 54.1 0.1 2.3 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NmrA PF05368.8 KLO10740.1 - 2.6e-11 43.2 0.6 1.6e-10 40.6 0.4 1.9 2 0 0 2 2 2 1 NmrA-like family NAD_binding_4 PF07993.7 KLO10740.1 - 8.7e-09 34.6 0.0 0.00033 19.6 0.0 2.2 2 0 0 2 2 2 2 Male sterility protein Polysacc_synt_2 PF02719.10 KLO10740.1 - 3.6e-06 26.1 0.5 6.8e-06 25.1 0.3 1.4 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Mur_ligase PF01225.20 KLO10740.1 - 0.0014 18.6 0.2 0.12 12.4 0.1 2.5 1 1 1 2 2 2 1 Mur ligase family, catalytic domain RmlD_sub_bind PF04321.12 KLO10740.1 - 0.02 13.7 0.5 0.5 9.1 0.0 2.4 2 1 0 2 2 2 0 RmlD substrate binding domain adh_short PF00106.20 KLO10740.1 - 0.078 12.8 7.0 0.1 12.4 0.7 3.3 3 2 0 3 3 3 0 short chain dehydrogenase Ferritin_2 PF13668.1 KLO10742.1 - 4.4e-43 146.5 1.6 6.6e-43 145.9 1.1 1.3 1 0 0 1 1 1 1 Ferritin-like domain SKG6 PF08693.5 KLO10743.1 - 0.00044 19.4 0.1 0.00086 18.5 0.1 1.5 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Beta-APP PF03494.8 KLO10743.1 - 0.019 14.3 1.9 0.037 13.4 1.3 1.4 1 0 0 1 1 1 0 Beta-amyloid peptide (beta-APP) CD99L2 PF12301.3 KLO10743.1 - 0.044 13.4 0.7 0.075 12.7 0.5 1.3 1 0 0 1 1 1 0 CD99 antigen like protein 2 Syndecan PF01034.15 KLO10743.1 - 0.063 12.9 0.1 0.13 11.8 0.0 1.5 1 0 0 1 1 1 0 Syndecan domain PDGLE PF13190.1 KLO10743.1 - 0.087 12.5 0.9 0.16 11.6 0.6 1.5 1 0 0 1 1 1 0 PDGLE domain Plasmodium_Vir PF05795.6 KLO10743.1 - 0.11 11.6 0.2 0.15 11.2 0.1 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein P12 PF12669.2 KLO10743.1 - 0.61 10.3 0.1 0.61 10.3 0.0 2.3 3 0 0 3 3 3 0 Virus attachment protein p12 family NifU PF01106.12 KLO10743.1 - 0.68 9.7 3.5 0.76 9.5 0.6 2.1 2 0 0 2 2 2 0 NifU-like domain Phage_Coat_B PF05356.6 KLO10743.1 - 2.3 7.9 5.0 3.3 7.4 1.6 2.5 1 1 1 2 2 2 0 Phage Coat protein B DUF515 PF04415.7 KLO10743.1 - 6.2 4.9 8.3 9.6 4.3 5.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF515) SKG6 PF08693.5 KLO10744.1 - 0.017 14.4 1.1 0.017 14.4 0.8 2.2 2 0 0 2 2 2 0 Transmembrane alpha-helix domain Herpes_gE PF02480.11 KLO10745.1 - 0.0013 17.1 0.0 0.0018 16.6 0.0 1.2 1 0 0 1 1 1 1 Alphaherpesvirus glycoprotein E Syndecan PF01034.15 KLO10745.1 - 0.16 11.6 0.0 0.32 10.6 0.0 1.4 1 0 0 1 1 1 0 Syndecan domain P12 PF12669.2 KLO10747.1 - 0.32 11.2 0.1 0.32 11.2 0.1 2.3 2 0 0 2 2 2 0 Virus attachment protein p12 family Adeno_E3_CR2 PF02439.10 KLO10748.1 - 0.052 13.1 0.8 0.09 12.3 0.6 1.3 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 DUF3708 PF12501.3 KLO10748.1 - 0.065 13.0 1.1 0.19 11.5 0.8 1.7 1 0 0 1 1 1 0 Phosphate ATP-binding cassette transporter EphA2_TM PF14575.1 KLO10748.1 - 0.13 12.6 0.0 0.29 11.5 0.0 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain SDF PF00375.13 KLO10748.1 - 0.48 9.1 6.7 0.79 8.4 4.6 1.2 1 0 0 1 1 1 0 Sodium:dicarboxylate symporter family TFIIA PF03153.8 KLO10748.1 - 0.5 10.2 5.3 0.7 9.7 3.7 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF1180 PF06679.7 KLO10748.1 - 1.1 9.1 8.6 0.74 9.6 4.3 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1180) DUF2273 PF10031.4 KLO10748.1 - 1.8 8.2 5.8 3.1 7.4 4.0 1.2 1 0 0 1 1 1 0 Small integral membrane protein (DUF2273) DUF605 PF04652.11 KLO10748.1 - 2.3 7.5 14.8 3.8 6.7 10.3 1.3 1 0 0 1 1 1 0 Vta1 like Ribosomal_L30_N PF08079.7 KLO10749.1 - 5e-25 87.3 19.8 1e-24 86.2 13.7 1.6 1 0 0 1 1 1 1 Ribosomal L30 N-terminal domain Ribosomal_L30 PF00327.15 KLO10749.1 - 5.3e-20 70.7 1.2 1.2e-19 69.6 0.5 1.9 2 0 0 2 2 2 1 Ribosomal protein L30p/L7e Consortin_C PF15281.1 KLO10749.1 - 0.24 10.9 1.7 0.4 10.1 1.2 1.4 1 0 0 1 1 1 0 Consortin C-terminus CMD PF02627.15 KLO10751.1 - 5.2e-10 39.0 0.4 4.9e-09 35.9 0.0 2.0 2 0 0 2 2 2 1 Carboxymuconolactone decarboxylase family CLTH PF10607.4 KLO10752.1 - 2.3e-19 69.5 0.0 4e-19 68.7 0.0 1.4 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain LisH PF08513.6 KLO10752.1 - 1.9e-06 27.3 0.0 4e-06 26.3 0.0 1.5 1 0 0 1 1 1 1 LisH PhnA_Zn_Ribbon PF08274.7 KLO10754.1 - 0.008 15.9 0.2 0.037 13.8 0.0 2.1 2 0 0 2 2 2 1 PhnA Zinc-Ribbon YHS PF04945.8 KLO10754.1 - 0.044 13.6 0.2 0.094 12.5 0.1 1.5 1 0 0 1 1 1 0 YHS domain RtcB PF01139.12 KLO10755.1 - 1.3e-79 268.2 0.0 1e-77 261.9 0.0 2.1 1 1 0 1 1 1 1 tRNA-splicing ligase RtcB BTB PF00651.26 KLO10756.1 - 0.0087 16.0 0.0 0.015 15.2 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain Pro-MCH PF05824.7 KLO10756.1 - 0.012 15.0 0.0 1.2 8.6 0.0 2.4 2 0 0 2 2 2 0 Pro-melanin-concentrating hormone (Pro-MCH) PNTB PF02233.11 KLO10757.1 - 2.2e-171 570.6 22.8 2.2e-171 570.6 15.8 1.6 2 0 0 2 2 1 1 NAD(P) transhydrogenase beta subunit AlaDh_PNT_C PF01262.16 KLO10757.1 - 4.1e-52 176.1 0.5 8.9e-52 175.0 0.3 1.5 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain AlaDh_PNT_N PF05222.10 KLO10757.1 - 6.1e-44 149.3 0.0 2.4e-43 147.3 0.0 2.0 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, N-terminal domain DUF3814 PF12769.2 KLO10757.1 - 7.3e-32 109.3 5.1 7.3e-32 109.3 3.6 4.6 4 2 1 5 5 5 1 Domain of unknown function (DUF3814) 2-Hacid_dh_C PF02826.14 KLO10757.1 - 0.00054 19.1 0.0 0.7 9.0 0.0 3.2 3 0 0 3 3 3 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ADH_zinc_N PF00107.21 KLO10757.1 - 0.0066 15.9 0.1 0.025 14.1 0.1 2.1 1 1 0 1 1 1 1 Zinc-binding dehydrogenase Pyr_redox_2 PF07992.9 KLO10757.1 - 0.036 13.9 0.7 0.092 12.6 0.5 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Methyltransf_31 PF13847.1 KLO10757.1 - 0.036 13.6 0.0 0.14 11.7 0.0 1.9 1 1 0 1 1 1 0 Methyltransferase domain Pyr_redox_3 PF13738.1 KLO10757.1 - 0.052 13.6 0.3 5.2 7.0 0.1 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase tRNA_synt_2f PF02092.12 KLO10757.1 - 0.38 9.2 0.0 0.56 8.6 0.0 1.1 1 0 0 1 1 1 0 Glycyl-tRNA synthetase beta subunit Shikimate_DH PF01488.15 KLO10757.1 - 0.58 10.2 4.8 12 5.9 0.0 3.6 4 1 0 4 4 3 0 Shikimate / quinate 5-dehydrogenase NAD_binding_8 PF13450.1 KLO10757.1 - 6.4 6.8 9.4 0.69 9.9 1.7 3.1 3 1 0 3 3 3 0 NAD(P)-binding Rossmann-like domain BTB PF00651.26 KLO10758.1 - 8.7e-05 22.4 0.0 0.00034 20.5 0.0 1.9 1 1 0 1 1 1 1 BTB/POZ domain F-box-like PF12937.2 KLO10759.1 - 0.00021 20.9 1.1 0.00043 19.9 0.1 2.1 2 0 0 2 2 2 1 F-box-like LRR_8 PF13855.1 KLO10759.1 - 0.0085 15.8 1.2 2.2 8.0 0.0 3.5 3 0 0 3 3 3 2 Leucine rich repeat F-box PF00646.28 KLO10759.1 - 0.011 15.3 0.4 0.011 15.3 0.3 2.2 2 0 0 2 2 2 0 F-box domain Chlamy_scaf PF09675.5 KLO10759.1 - 0.012 15.6 0.0 0.024 14.6 0.0 1.4 1 0 0 1 1 1 0 Chlamydia-phage Chp2 scaffold (Chlamy_scaf) F-box-like PF12937.2 KLO10760.1 - 2.4e-05 23.9 0.2 8.8e-05 22.1 0.2 2.0 1 0 0 1 1 1 1 F-box-like LRR_8 PF13855.1 KLO10760.1 - 6.5e-05 22.6 8.1 2.1 8.1 0.6 6.2 6 1 0 6 6 6 2 Leucine rich repeat F-box PF00646.28 KLO10760.1 - 0.00076 19.0 0.7 0.0024 17.4 0.5 1.9 1 0 0 1 1 1 1 F-box domain ATP-synt_C PF00137.16 KLO10764.1 - 0.0007 19.4 3.4 0.0013 18.5 2.4 1.5 1 0 0 1 1 1 1 ATP synthase subunit C PASTA PF03793.14 KLO10765.1 - 0.044 13.4 0.1 0.08 12.6 0.1 1.4 1 0 0 1 1 1 0 PASTA domain DM PF00751.13 KLO10766.1 - 0.078 12.5 0.7 0.19 11.3 0.5 1.5 1 0 0 1 1 1 0 DM DNA binding domain PDH PF02153.12 KLO10768.1 - 5.6e-14 51.6 0.0 7.2e-14 51.2 0.0 1.1 1 0 0 1 1 1 1 Prephenate dehydrogenase F420_oxidored PF03807.12 KLO10768.1 - 5.6e-07 29.9 0.0 1.5e-06 28.5 0.0 1.7 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.10 KLO10768.1 - 4.4e-06 26.6 0.0 7.8e-06 25.8 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase Shikimate_DH PF01488.15 KLO10768.1 - 0.0074 16.3 0.0 0.015 15.3 0.0 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase 2-Hacid_dh_C PF02826.14 KLO10768.1 - 0.013 14.6 0.0 0.023 13.8 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain TrkA_N PF02254.13 KLO10768.1 - 0.033 14.1 0.0 0.064 13.2 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain 3HCDH_N PF02737.13 KLO10768.1 - 0.043 13.4 0.1 0.21 11.2 0.0 1.9 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_Gly3P_dh_N PF01210.18 KLO10768.1 - 0.12 12.1 0.0 0.24 11.1 0.0 1.5 1 1 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Tweety PF04906.8 KLO10769.1 - 0.69 8.2 2.9 0.97 7.7 2.0 1.1 1 0 0 1 1 1 0 Tweety zf-MYND PF01753.13 KLO10771.1 - 2.1e-10 40.2 9.5 4.3e-10 39.2 6.6 1.5 1 0 0 1 1 1 1 MYND finger PHF5 PF03660.9 KLO10771.1 - 0.12 12.4 3.9 0.25 11.4 2.7 1.5 1 0 0 1 1 1 0 PHF5-like protein RecR PF02132.10 KLO10771.1 - 2.2 7.7 5.4 1.1 8.7 1.2 2.5 3 0 0 3 3 3 0 RecR protein zf-MYND PF01753.13 KLO10772.1 - 1.8e-11 43.6 11.8 4.3e-11 42.5 8.1 1.7 1 0 0 1 1 1 1 MYND finger DHHA1 PF02272.14 KLO10772.1 - 0.022 14.4 0.0 0.062 13.0 0.0 1.7 1 0 0 1 1 1 0 DHHA1 domain PHF5 PF03660.9 KLO10772.1 - 0.73 9.9 9.0 0.065 13.2 2.8 1.7 2 0 0 2 2 2 0 PHF5-like protein TPT PF03151.11 KLO10773.1 - 5.2e-29 100.8 14.3 6.5e-25 87.5 2.3 2.2 2 0 0 2 2 2 2 Triose-phosphate Transporter family UAA PF08449.6 KLO10773.1 - 1.8e-11 43.5 11.4 2.3e-07 30.0 2.7 2.2 2 0 0 2 2 2 2 UAA transporter family EamA PF00892.15 KLO10773.1 - 1.3e-07 31.7 27.8 8.1e-05 22.6 7.2 2.9 3 0 0 3 3 3 2 EamA-like transporter family EmrE PF13536.1 KLO10773.1 - 0.00096 19.3 21.4 0.0056 16.8 3.1 3.4 2 1 2 4 4 4 2 Multidrug resistance efflux transporter Trep_Strep PF09605.5 KLO10773.1 - 0.12 12.0 7.7 0.37 10.4 5.3 1.8 1 0 0 1 1 1 0 Hypothetical bacterial integral membrane protein (Trep_Strep) F-box-like PF12937.2 KLO10774.1 - 1.1e-05 24.9 0.7 1.1e-05 24.9 0.5 2.9 3 0 0 3 3 3 1 F-box-like F-box PF00646.28 KLO10774.1 - 1.1 8.9 11.8 4.1 7.1 0.0 4.1 4 0 0 4 4 4 0 F-box domain F-box-like PF12937.2 KLO10775.1 - 1.3e-05 24.8 3.8 7.2e-05 22.4 2.6 2.4 2 0 0 2 2 2 1 F-box-like zf-MYND PF01753.13 KLO10780.1 - 2.5e-05 24.0 12.2 5.6e-05 22.9 8.4 1.7 1 0 0 1 1 1 1 MYND finger DUF2256 PF10013.4 KLO10780.1 - 7 6.4 9.0 48 3.8 6.2 2.3 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2256) F-box-like PF12937.2 KLO10781.1 - 0.00036 20.1 3.3 0.0013 18.3 2.3 2.0 1 1 0 1 1 1 1 F-box-like F-box PF00646.28 KLO10781.1 - 0.015 14.9 2.3 0.14 11.8 1.1 2.7 2 0 0 2 2 2 0 F-box domain F-box-like PF12937.2 KLO10782.1 - 2.1e-05 24.1 5.6 8e-05 22.2 3.1 2.6 2 1 0 2 2 2 1 F-box-like F-box-like PF12937.2 KLO10783.1 - 5.6e-05 22.7 1.9 8.9e-05 22.1 0.2 2.2 2 0 0 2 2 2 1 F-box-like DUF3407 PF11887.3 KLO10783.1 - 0.063 12.5 0.0 0.1 11.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3407) 3-alpha PF03475.9 KLO10783.1 - 0.1 12.3 0.1 0.21 11.3 0.0 1.5 1 0 0 1 1 1 0 3-alpha domain zf-MYND PF01753.13 KLO10784.1 - 6.4e-10 38.7 11.0 1.4e-09 37.6 7.6 1.6 1 0 0 1 1 1 1 MYND finger Ecl1 PF12855.2 KLO10784.1 - 0.11 11.8 4.6 0.25 10.6 3.2 1.5 1 0 0 1 1 1 0 Life-span regulatory factor DIM PF08194.7 KLO10789.1 - 7.4 6.6 6.0 0.58 10.1 0.3 2.0 2 0 0 2 2 2 0 DIM protein P16-Arc PF04699.9 KLO10791.1 - 0.003 17.5 0.0 0.0067 16.4 0.0 1.6 1 0 0 1 1 1 1 ARP2/3 complex 16 kDa subunit (p16-Arc) DUF605 PF04652.11 KLO10794.1 - 1 8.6 9.6 1.2 8.4 6.6 1.2 1 0 0 1 1 1 0 Vta1 like Ricin_B_lectin PF00652.17 KLO10795.1 - 7.7e-20 71.1 7.2 7.7e-20 71.1 5.0 1.8 2 0 0 2 2 2 1 Ricin-type beta-trefoil lectin domain RicinB_lectin_2 PF14200.1 KLO10795.1 - 4.6e-15 55.8 9.7 2.2e-09 37.6 3.3 2.6 1 1 1 2 2 2 2 Ricin-type beta-trefoil lectin domain-like zf-MYND PF01753.13 KLO10796.1 - 4.5e-07 29.6 7.7 8.9e-07 28.6 5.3 1.5 1 0 0 1 1 1 1 MYND finger zf-Mss51 PF13824.1 KLO10796.1 - 0.009 15.8 4.0 0.009 15.8 2.7 2.1 2 0 0 2 2 2 1 Zinc-finger of mitochondrial splicing suppressor 51 F-box-like PF12937.2 KLO10797.1 - 1.4e-05 24.6 1.4 6.3e-05 22.6 0.0 2.9 2 0 0 2 2 2 1 F-box-like IL2 PF00715.12 KLO10797.1 - 0.033 13.9 0.0 0.073 12.7 0.0 1.6 1 0 0 1 1 1 0 Interleukin 2 F-box-like PF12937.2 KLO10798.1 - 0.00024 20.7 3.7 0.00024 20.7 2.6 3.1 3 2 0 3 3 3 1 F-box-like Phenol_hyd_sub PF06099.6 KLO10799.1 - 0.022 14.5 0.1 0.042 13.6 0.0 1.5 1 0 0 1 1 1 0 Phenol hydroxylase subunit zf-MYND PF01753.13 KLO10800.1 - 5.3e-06 26.2 10.9 1.4e-05 24.8 7.5 1.7 1 0 0 1 1 1 1 MYND finger zf-Mss51 PF13824.1 KLO10800.1 - 4.8 7.1 9.4 13 5.7 6.5 1.7 1 0 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 zf-MYND PF01753.13 KLO10801.1 - 8.4e-08 31.9 10.9 1.6e-07 31.0 7.6 1.5 1 0 0 1 1 1 1 MYND finger zf-MYND PF01753.13 KLO10802.1 - 6.5e-07 29.1 3.0 1.4e-06 28.0 2.1 1.6 1 0 0 1 1 1 1 MYND finger zf-Mss51 PF13824.1 KLO10802.1 - 0.23 11.3 1.7 0.53 10.1 1.2 1.6 1 0 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 C1_1 PF00130.17 KLO10802.1 - 0.67 9.7 5.0 0.3 10.8 1.0 2.2 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) p450 PF00067.17 KLO10803.1 - 9.5e-50 169.4 0.0 1.1e-49 169.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Mst1_SARAH PF11629.3 KLO10804.1 - 0.24 11.2 1.9 5.2 6.9 0.0 2.6 2 0 0 2 2 2 0 C terminal SARAH domain of Mst1 p450 PF00067.17 KLO10805.1 - 0.00071 18.2 0.0 0.00099 17.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 KLO10806.1 - 1.7e-59 201.5 0.0 2.2e-59 201.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 KLO10807.1 - 5.3e-08 31.8 0.0 6.5e-08 31.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 YL1 PF05764.8 KLO10813.1 - 0.0057 16.2 1.8 0.0057 16.2 1.2 2.3 2 0 0 2 2 2 1 YL1 nuclear protein E1-E2_ATPase PF00122.15 KLO10815.1 - 2.1e-59 200.3 0.8 2.1e-59 200.3 0.6 1.8 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 KLO10815.1 - 7.4e-45 152.7 4.4 7.4e-45 152.7 3.1 2.8 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 KLO10815.1 - 9.4e-27 94.8 0.0 6.4e-25 88.8 0.0 3.2 2 2 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 KLO10815.1 - 9.8e-19 67.1 0.0 2.2e-18 65.9 0.0 1.6 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 KLO10815.1 - 5.1e-14 52.8 0.0 3.4e-13 50.1 0.0 2.4 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 KLO10815.1 - 1.7e-07 30.5 0.1 1.7e-07 30.5 0.0 2.1 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 KLO10815.1 - 0.00013 21.6 0.8 0.014 14.9 0.4 2.3 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Pam17 PF08566.5 KLO10815.1 - 0.85 9.2 5.8 1.1 8.9 0.0 3.1 4 0 0 4 4 4 0 Mitochondrial import protein Pam17 Herpes_IR6 PF06307.7 KLO10817.1 - 0.092 12.0 0.0 0.11 11.7 0.0 1.1 1 0 0 1 1 1 0 Herpesvirus IR6 protein Mito_fiss_reg PF05308.6 KLO10817.1 - 0.096 12.0 0.8 0.13 11.6 0.5 1.1 1 0 0 1 1 1 0 Mitochondrial fission regulator DUF3450 PF11932.3 KLO10821.1 - 0.0067 15.7 0.1 0.0084 15.4 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3450) PEX11 PF05648.9 KLO10823.1 - 8.4e-14 51.3 0.1 1.9e-12 46.9 0.0 2.2 1 1 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) zf-C2H2_4 PF13894.1 KLO10824.1 - 0.0023 18.1 12.0 0.073 13.4 0.4 3.3 3 0 0 3 3 3 2 C2H2-type zinc finger DNA_pol_phi PF04931.8 KLO10824.1 - 2.4 5.8 14.6 3.7 5.2 10.1 1.2 1 0 0 1 1 1 0 DNA polymerase phi zf-C2H2 PF00096.21 KLO10824.1 - 7.7 7.0 14.7 2 8.9 1.1 3.4 3 0 0 3 3 3 0 Zinc finger, C2H2 type Glyco_hydro_10 PF00331.15 KLO10825.1 - 2.6e-99 332.3 0.1 2.9e-99 332.1 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 CBM_1 PF00734.13 KLO10825.1 - 3.1e-14 52.3 9.2 3.1e-14 52.3 6.4 2.2 2 0 0 2 2 2 1 Fungal cellulose binding domain Glyco_hydro_42 PF02449.10 KLO10825.1 - 0.028 13.5 0.0 0.063 12.3 0.0 1.6 1 1 1 2 2 2 0 Beta-galactosidase YqgF PF14639.1 KLO10825.1 - 0.16 11.5 0.0 0.26 10.8 0.0 1.2 1 0 0 1 1 1 0 Holliday-junction resolvase-like of SPT6 Mito_fiss_reg PF05308.6 KLO10827.1 - 0.43 9.8 7.6 0.77 9.0 5.2 1.4 1 0 0 1 1 1 0 Mitochondrial fission regulator Tubulin PF00091.20 KLO10828.1 - 2e-67 227.1 0.0 3.2e-67 226.5 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 KLO10828.1 - 7.6e-43 145.5 0.0 1.3e-42 144.7 0.0 1.4 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.4 KLO10828.1 - 6.1e-06 26.2 0.0 1.5e-05 25.0 0.0 1.6 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain DUF4078 PF13300.1 KLO10829.1 - 1.8e-18 66.4 3.3 1.8e-18 66.4 2.3 4.2 4 1 0 4 4 4 2 Domain of unknown function (DUF4078) HrpA_pilin PF09589.5 KLO10829.1 - 0.013 15.9 1.0 0.013 15.9 0.7 2.2 3 0 0 3 3 3 0 HrpA pilus formation protein Vps39_1 PF10366.4 KLO10830.1 - 1.5e-26 92.4 0.0 1.9e-25 88.9 0.0 2.9 2 0 0 2 2 2 1 Vacuolar sorting protein 39 domain 1 Vps39_2 PF10367.4 KLO10830.1 - 5.4e-20 71.5 0.3 1.4e-19 70.2 0.2 1.8 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 2 CNH PF00780.17 KLO10830.1 - 5.2e-11 42.4 0.0 1.8e-10 40.7 0.0 1.8 1 1 0 1 1 1 1 CNH domain Clathrin PF00637.15 KLO10830.1 - 1.9e-08 33.9 0.0 8.2e-05 22.2 0.0 2.6 2 0 0 2 2 2 2 Region in Clathrin and VPS TPR_1 PF00515.23 KLO10830.1 - 0.023 14.3 0.9 29 4.5 0.0 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF4428 PF14471.1 KLO10830.1 - 0.11 12.2 0.0 0.25 11.1 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4428) TPR_16 PF13432.1 KLO10830.1 - 2.9 8.6 5.1 4.7 8.0 0.6 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat Gastrin PF00918.12 KLO10831.1 - 0.12 13.2 0.2 0.24 12.1 0.1 1.5 1 0 0 1 1 1 0 Gastrin/cholecystokinin family RRM_1 PF00076.17 KLO10832.1 - 0.0033 17.0 0.0 0.0065 16.0 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KLO10832.1 - 0.011 15.6 0.0 0.02 14.8 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KLO10832.1 - 0.15 11.9 0.1 0.24 11.2 0.1 1.3 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SPT2 PF08243.6 KLO10833.1 - 1.9e-13 50.7 16.8 1.9e-13 50.7 11.6 4.5 4 1 1 5 5 5 2 SPT2 chromatin protein COesterase PF00135.23 KLO10834.1 - 9e-101 338.1 0.0 1.1e-100 337.8 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 KLO10834.1 - 0.0021 17.6 0.0 0.0035 16.9 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.23 KLO10835.1 - 3.3e-94 316.5 0.0 4.3e-94 316.1 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 KLO10835.1 - 0.00021 20.9 0.0 0.00037 20.1 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Pkinase PF00069.20 KLO10839.1 - 3.2e-79 265.7 0.0 6.6e-46 156.5 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 KLO10839.1 - 6.2e-77 258.1 0.0 2e-39 135.2 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Zn_clus PF00172.13 KLO10839.1 - 1e-07 31.7 7.8 1e-07 31.7 5.4 2.2 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Kinase-like PF14531.1 KLO10839.1 - 2.6e-07 29.8 0.0 0.005 15.8 0.0 2.3 2 0 0 2 2 2 2 Kinase-like Kdo PF06293.9 KLO10839.1 - 0.00063 18.8 0.0 0.11 11.5 0.0 2.5 3 0 0 3 3 3 2 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KLO10839.1 - 0.00075 19.3 0.0 0.38 10.4 0.0 2.3 2 0 0 2 2 2 2 Phosphotransferase enzyme family RIO1 PF01163.17 KLO10839.1 - 0.0022 17.4 0.1 2.7 7.3 0.0 3.1 3 0 0 3 3 3 2 RIO1 family Pkinase_Tyr PF07714.12 KLO10840.1 - 4.3e-79 265.2 0.0 1.2e-39 136.0 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.20 KLO10840.1 - 2.5e-78 262.8 0.0 2.3e-45 154.8 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Kinase-like PF14531.1 KLO10840.1 - 9.6e-11 41.1 0.0 0.00014 20.9 0.0 2.2 2 0 0 2 2 2 2 Kinase-like RIO1 PF01163.17 KLO10840.1 - 5.2e-05 22.6 0.0 0.23 10.7 0.0 2.8 3 0 0 3 3 3 2 RIO1 family Zn_clus PF00172.13 KLO10840.1 - 0.00015 21.6 10.3 0.00015 21.6 7.1 2.5 3 0 0 3 3 3 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Kdo PF06293.9 KLO10840.1 - 0.0012 18.0 0.0 0.6 9.1 0.0 2.3 2 0 0 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KLO10840.1 - 0.0018 18.0 0.0 2.6 7.7 0.0 2.6 2 0 0 2 2 2 2 Phosphotransferase enzyme family Pkinase PF00069.20 KLO10841.1 - 2e-45 154.9 0.0 2.9e-45 154.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KLO10841.1 - 2.8e-42 144.5 0.0 4e-42 144.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KLO10841.1 - 9.5e-06 24.7 0.0 1.6e-05 24.0 0.0 1.2 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.17 KLO10841.1 - 0.0073 15.6 0.3 0.028 13.7 0.0 1.9 2 0 0 2 2 2 1 RIO1 family Kdo PF06293.9 KLO10841.1 - 0.077 12.0 0.0 0.13 11.3 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KLO10841.1 - 0.096 12.4 0.0 0.19 11.4 0.0 1.6 1 0 0 1 1 1 0 Phosphotransferase enzyme family F-box-like PF12937.2 KLO10842.1 - 1.3e-05 24.8 2.0 1.7e-05 24.4 0.3 2.1 2 0 0 2 2 2 1 F-box-like DUF3507 PF12015.3 KLO10846.1 - 0.041 13.3 0.0 0.044 13.2 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3507) GMC_oxred_N PF00732.14 KLO10847.1 - 1e-53 182.4 0.0 1.5e-53 181.9 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 KLO10847.1 - 1.8e-34 119.0 0.0 3.2e-34 118.2 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase Peptidase_M1 PF01433.15 KLO10848.1 - 5.3e-18 65.2 0.0 9.7e-18 64.4 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M1 ERAP1_C PF11838.3 KLO10848.1 - 3.4e-15 56.1 2.9 1.9e-08 33.9 0.1 2.5 2 1 0 2 2 2 2 ERAP1-like C-terminal domain COX8 PF02285.10 KLO10848.1 - 0.0024 17.3 0.0 0.0066 15.9 0.0 1.7 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIII Thiolase_N PF00108.18 KLO10849.1 - 6.9e-83 277.6 6.5 6.9e-83 277.6 4.5 1.7 2 1 0 2 2 2 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 KLO10849.1 - 9.4e-44 147.7 0.7 2.5e-43 146.4 0.5 1.7 1 0 0 1 1 1 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.21 KLO10849.1 - 0.039 13.4 4.2 0.052 13.0 1.0 2.4 3 0 0 3 3 3 0 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.5 KLO10849.1 - 0.073 12.7 0.9 14 5.4 0.1 2.7 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III FTCD_C PF04961.7 KLO10849.1 - 0.1 12.0 3.9 0.64 9.4 0.5 2.6 2 0 0 2 2 2 0 Formiminotransferase-cyclodeaminase CVNH PF08881.5 KLO10855.1 - 1.6e-18 66.8 0.1 2.2e-18 66.3 0.1 1.2 1 0 0 1 1 1 1 CVNH domain NABP PF07990.7 KLO10855.1 - 0.031 13.5 0.9 0.037 13.3 0.6 1.0 1 0 0 1 1 1 0 Nucleic acid binding protein NABP DUF3367 PF11847.3 KLO10856.1 - 0.083 10.8 0.0 0.1 10.5 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3367) CVNH PF08881.5 KLO10857.1 - 6.6e-20 71.2 0.4 7.9e-20 71.0 0.3 1.1 1 0 0 1 1 1 1 CVNH domain Ricin_B_lectin PF00652.17 KLO10857.1 - 0.071 13.1 0.3 1.4 9.0 0.2 2.0 1 1 1 2 2 2 0 Ricin-type beta-trefoil lectin domain GATA PF00320.22 KLO10858.1 - 6.9e-09 34.8 7.9 9.3e-09 34.4 5.5 1.2 1 0 0 1 1 1 1 GATA zinc finger ArfGap PF01412.13 KLO10858.1 - 0.017 14.9 1.0 0.019 14.7 0.7 1.1 1 0 0 1 1 1 0 Putative GTPase activating protein for Arf DUF4611 PF15387.1 KLO10859.1 - 0.069 13.2 4.5 0.17 12.0 3.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) Nucleoplasmin PF03066.10 KLO10859.1 - 0.18 11.2 6.7 0.34 10.4 4.7 1.4 1 0 0 1 1 1 0 Nucleoplasmin PBP1_TM PF14812.1 KLO10859.1 - 0.2 11.9 7.4 1.2 9.4 5.7 1.8 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal CENP-B_dimeris PF09026.5 KLO10859.1 - 0.61 10.3 8.9 1.6 9.0 6.0 1.7 2 0 0 2 2 2 0 Centromere protein B dimerisation domain YL1 PF05764.8 KLO10859.1 - 1.9 8.0 6.1 2.8 7.4 4.2 1.2 1 0 0 1 1 1 0 YL1 nuclear protein Bd3614_N PF14442.1 KLO10859.1 - 7.5 6.5 10.2 14 5.6 7.0 1.4 1 0 0 1 1 1 0 Bd3614-like deaminase N-terminal COesterase PF00135.23 KLO10861.1 - 5.4e-56 190.4 0.0 7.3e-56 189.9 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 KLO10861.1 - 7.9e-09 35.3 0.4 3.6e-08 33.2 0.1 2.2 2 1 0 2 2 2 1 alpha/beta hydrolase fold F-box-like PF12937.2 KLO10862.1 - 1.9e-06 27.4 0.3 1.9e-06 27.4 0.2 1.9 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 KLO10862.1 - 0.0013 18.3 1.0 0.0013 18.3 0.7 2.4 2 0 0 2 2 2 1 F-box domain Sec1 PF00995.18 KLO10864.1 - 3.3e-119 399.0 0.0 9.6e-87 291.9 0.0 2.0 2 0 0 2 2 2 2 Sec1 family Peptidase_S10 PF00450.17 KLO10865.1 - 1.8e-67 228.3 1.6 9.2e-67 225.9 1.1 1.9 1 1 0 1 1 1 1 Serine carboxypeptidase Peptidase_M1 PF01433.15 KLO10866.1 - 2.5e-109 365.9 0.0 3.4e-109 365.4 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M1 ERAP1_C PF11838.3 KLO10866.1 - 3.5e-55 187.5 0.4 4.8e-55 187.0 0.3 1.2 1 0 0 1 1 1 1 ERAP1-like C-terminal domain Peptidase_MA_2 PF13485.1 KLO10866.1 - 3.2e-13 49.8 0.0 1.4e-12 47.7 0.0 2.1 2 0 0 2 2 2 1 Peptidase MA superfamily DUF3958 PF13125.1 KLO10866.1 - 0.13 12.1 0.3 0.42 10.5 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3958) CVNH PF08881.5 KLO10867.1 - 5.9e-13 48.9 0.2 9.8e-13 48.2 0.1 1.4 1 0 0 1 1 1 1 CVNH domain PMC2NT PF08066.7 KLO10867.1 - 0.12 12.6 0.0 0.22 11.8 0.0 1.4 1 0 0 1 1 1 0 PMC2NT (NUC016) domain MCM PF00493.18 KLO10868.1 - 0.0037 16.1 0.0 0.0046 15.8 0.0 1.1 1 0 0 1 1 1 1 MCM2/3/5 family DUF4217 PF13959.1 KLO10869.1 - 4.8e-08 32.4 0.2 1.9e-07 30.4 0.2 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) DEAD PF00270.24 KLO10869.1 - 3.3e-05 23.4 0.3 0.065 12.7 0.0 2.9 2 1 1 3 3 3 2 DEAD/DEAH box helicase Helicase_C PF00271.26 KLO10869.1 - 0.0039 17.0 0.0 0.011 15.6 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF221 PF02714.10 KLO10870.1 - 2.3e-90 302.7 17.6 4.1e-90 301.9 12.2 1.4 1 0 0 1 1 1 1 Domain of unknown function DUF221 RSN1_TM PF13967.1 KLO10870.1 - 2e-37 128.1 0.5 2e-37 128.1 0.3 3.1 3 0 0 3 3 3 1 Late exocytosis, associated with Golgi transport DUF4463 PF14703.1 KLO10870.1 - 6.8e-14 52.1 0.0 1.5e-13 51.0 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4463) BCS1_N PF08740.6 KLO10871.1 - 2.4e-32 112.0 0.6 5.2e-32 110.9 0.4 1.6 1 0 0 1 1 1 1 BCS1 N terminal AAA PF00004.24 KLO10871.1 - 7.5e-13 48.8 0.0 5.9e-06 26.5 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 KLO10871.1 - 0.00088 20.0 0.1 0.0047 17.7 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 KLO10871.1 - 0.0013 18.7 0.1 0.0047 16.9 0.0 2.0 2 0 0 2 2 2 1 AAA ATPase domain AAA_18 PF13238.1 KLO10871.1 - 0.012 15.9 0.3 0.086 13.1 0.0 2.5 3 0 0 3 3 3 0 AAA domain AAA_33 PF13671.1 KLO10871.1 - 0.017 15.0 0.0 0.04 13.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain DUF815 PF05673.8 KLO10871.1 - 0.02 13.8 0.0 0.033 13.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_19 PF13245.1 KLO10871.1 - 0.045 13.5 0.0 0.12 12.0 0.0 1.7 1 0 0 1 1 1 0 Part of AAA domain AAA_22 PF13401.1 KLO10871.1 - 0.056 13.5 0.0 0.11 12.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain RuvB_N PF05496.7 KLO10871.1 - 0.066 12.2 0.0 0.11 11.5 0.0 1.2 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus Viral_helicase1 PF01443.13 KLO10871.1 - 0.095 12.2 0.0 0.16 11.4 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_11 PF13086.1 KLO10871.1 - 0.1 12.1 0.0 0.19 11.3 0.0 1.6 1 1 0 1 1 1 0 AAA domain Lactamase_B PF00753.22 KLO10872.1 - 9.8e-09 35.1 0.1 3.9e-08 33.1 0.1 2.2 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 KLO10872.1 - 5.6e-05 22.7 0.1 0.00011 21.7 0.1 1.5 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 KLO10876.1 - 4.2e-09 36.3 0.5 1.9e-08 34.1 0.3 1.9 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 KLO10876.1 - 4.1e-06 26.4 0.1 4.9e-06 26.2 0.1 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain OPT PF03169.10 KLO10879.1 - 1.5e-183 611.6 47.6 1.7e-183 611.4 33.0 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein LRR_8 PF13855.1 KLO10880.1 - 1.7e-07 30.8 19.4 3.7e-05 23.3 0.7 3.6 3 0 0 3 3 3 2 Leucine rich repeat LRR_4 PF12799.2 KLO10880.1 - 2.7e-07 30.0 21.2 0.00041 19.9 0.6 5.1 3 1 2 5 5 5 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 KLO10880.1 - 1.3e-05 24.5 15.4 1.2 9.4 0.2 6.8 6 1 0 6 6 6 3 Leucine Rich Repeat LRR_6 PF13516.1 KLO10880.1 - 1.1 9.5 12.3 36 4.8 0.2 5.2 4 1 0 4 4 4 0 Leucine Rich repeat LRR_7 PF13504.1 KLO10880.1 - 7.8 7.1 12.2 97 3.8 0.1 6.0 5 0 0 5 5 5 0 Leucine rich repeat Calpain_III PF01067.17 KLO10881.1 - 8.3e-22 77.4 0.0 1.2e-08 34.7 0.0 4.7 4 1 0 4 4 4 3 Calpain large subunit, domain III Peptidase_C2 PF00648.16 KLO10881.1 - 9.5e-17 60.9 0.0 1.5e-16 60.2 0.0 1.2 1 0 0 1 1 1 1 Calpain family cysteine protease MIT PF04212.13 KLO10881.1 - 6.4e-05 22.7 6.0 0.00011 22.0 4.2 1.4 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain Init_tRNA_PT PF04179.7 KLO10882.1 - 2.8e-113 379.1 0.0 1.5e-76 258.1 0.0 2.0 2 0 0 2 2 2 2 Initiator tRNA phosphoribosyl transferase 3HCDH_N PF02737.13 KLO10883.1 - 2.9e-48 163.9 2.2 2e-47 161.1 1.5 2.0 1 1 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.17 KLO10883.1 - 5.9e-32 109.9 0.1 2.4e-31 108.0 0.0 2.1 3 0 0 3 3 3 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain NAD_binding_2 PF03446.10 KLO10883.1 - 0.0047 16.7 0.6 0.014 15.2 0.4 1.9 1 1 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase 2-Hacid_dh_C PF02826.14 KLO10883.1 - 0.081 12.0 0.1 0.14 11.2 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_Gly3P_dh_N PF01210.18 KLO10883.1 - 0.1 12.3 0.2 0.41 10.3 0.2 2.0 1 1 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus DDE_Tnp_4 PF13359.1 KLO10886.1 - 4.6e-17 62.0 0.0 5.3e-17 61.8 0.0 1.0 1 0 0 1 1 1 1 DDE superfamily endonuclease Plant_tran PF04827.9 KLO10886.1 - 0.0071 15.7 0.0 0.0082 15.5 0.0 1.1 1 0 0 1 1 1 1 Plant transposon protein TB2_DP1_HVA22 PF03134.14 KLO10886.1 - 0.026 14.2 0.0 0.042 13.5 0.0 1.3 1 0 0 1 1 1 0 TB2/DP1, HVA22 family Nipped-B_C PF12830.2 KLO10892.1 - 0.012 15.2 0.1 0.019 14.5 0.1 1.3 1 0 0 1 1 1 0 Sister chromatid cohesion C-terminus Hairy_orange PF07527.8 KLO10892.1 - 0.19 11.5 1.7 5.4 6.8 0.0 3.1 3 0 0 3 3 3 0 Hairy Orange DUF2945 PF11160.3 KLO10893.1 - 2.1e-05 24.2 0.0 0.00024 20.8 0.0 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF2945) Mito_carr PF00153.22 KLO10894.1 - 1.3e-48 162.6 0.3 6.8e-15 54.5 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein FAM196 PF15265.1 KLO10901.1 - 0.55 9.3 7.6 0.6 9.2 5.3 1.0 1 0 0 1 1 1 0 FAM196 family Pilus_PilP PF11356.3 KLO10901.1 - 3.2 8.0 4.9 5.8 7.2 3.4 1.4 1 0 0 1 1 1 0 Type IV pilus biogenesis TFIIA PF03153.8 KLO10901.1 - 5.4 6.8 8.3 6.1 6.6 5.8 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit CDC27 PF09507.5 KLO10901.1 - 7.2 5.7 10.5 8 5.5 7.2 1.0 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Cyclin_N PF00134.18 KLO10902.1 - 2.7e-12 46.3 0.0 3.4e-12 46.0 0.0 1.1 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.6 KLO10902.1 - 7.4e-08 32.9 0.0 8.2e-08 32.7 0.0 1.2 1 0 0 1 1 1 1 Cyclin Colipase PF01114.13 KLO10904.1 - 1 8.8 6.9 0.66 9.4 0.6 2.3 2 0 0 2 2 2 0 Colipase, N-terminal domain CENP-F_leu_zip PF10473.4 KLO10905.1 - 9.8e-05 22.2 9.1 0.0012 18.7 6.2 2.6 1 1 0 1 1 1 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF4455 PF14643.1 KLO10905.1 - 0.003 16.2 0.1 0.0054 15.4 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4455) TMF_DNA_bd PF12329.3 KLO10905.1 - 0.0033 17.2 6.0 0.0033 17.2 4.2 3.3 2 1 2 4 4 3 2 TATA element modulatory factor 1 DNA binding bZIP_1 PF00170.16 KLO10905.1 - 0.015 15.2 3.9 0.33 10.9 0.1 3.4 1 1 3 4 4 4 0 bZIP transcription factor DUF883 PF05957.8 KLO10905.1 - 0.018 15.4 0.6 0.064 13.6 0.3 2.1 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF883) Reo_sigmaC PF04582.7 KLO10905.1 - 0.02 14.1 9.4 0.13 11.4 4.6 2.7 2 1 1 3 3 3 0 Reovirus sigma C capsid protein APG6 PF04111.7 KLO10905.1 - 0.025 13.6 3.1 0.051 12.6 2.1 1.5 1 0 0 1 1 1 0 Autophagy protein Apg6 BCAS2 PF05700.6 KLO10905.1 - 0.027 13.9 3.2 0.07 12.5 2.2 1.8 1 0 0 1 1 1 0 Breast carcinoma amplified sequence 2 (BCAS2) Lectin_N PF03954.9 KLO10905.1 - 0.029 13.7 4.7 0.75 9.1 0.3 2.7 1 1 1 2 2 2 0 Hepatic lectin, N-terminal domain DUF730 PF05325.6 KLO10905.1 - 0.031 14.0 1.0 0.18 11.6 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF730) Phlebovirus_NSM PF07246.6 KLO10905.1 - 0.05 12.7 3.9 0.1 11.7 2.7 1.5 1 0 0 1 1 1 0 Phlebovirus nonstructural protein NS-M ADIP PF11559.3 KLO10905.1 - 0.077 12.8 9.3 0.26 11.1 0.1 3.3 2 1 1 3 3 3 0 Afadin- and alpha -actinin-Binding DUF1664 PF07889.7 KLO10905.1 - 0.22 11.3 7.6 3.5 7.4 1.1 2.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) DivIC PF04977.10 KLO10905.1 - 0.53 9.8 2.9 5.3 6.5 0.0 3.3 1 1 0 2 2 2 0 Septum formation initiator TPR_MLP1_2 PF07926.7 KLO10905.1 - 0.63 9.7 12.9 0.059 13.1 3.6 2.9 2 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein AAA_13 PF13166.1 KLO10905.1 - 0.72 8.2 10.3 0.036 12.5 2.4 2.1 2 0 0 2 2 2 0 AAA domain DUF904 PF06005.7 KLO10905.1 - 0.88 9.9 6.3 39 4.6 3.7 3.7 2 1 0 2 2 2 0 Protein of unknown function (DUF904) Striatin PF08232.7 KLO10905.1 - 2.4 8.4 6.3 0.22 11.8 0.2 2.5 2 1 0 3 3 3 0 Striatin family DUF972 PF06156.8 KLO10905.1 - 2.8 8.3 7.2 2.2 8.6 0.6 3.2 1 1 1 2 2 2 0 Protein of unknown function (DUF972) ATG16 PF08614.6 KLO10905.1 - 2.8 7.7 17.0 0.016 15.0 3.9 2.8 3 1 0 3 3 3 0 Autophagy protein 16 (ATG16) IncA PF04156.9 KLO10905.1 - 2.8 7.4 8.3 0.53 9.8 0.2 2.6 2 1 2 4 4 4 0 IncA protein Transposase_21 PF02992.9 KLO10906.1 - 7.9e-13 48.0 0.0 1.7e-11 43.6 0.0 2.3 2 0 0 2 2 2 2 Transposase family tnp2 Cyclin_N PF00134.18 KLO10907.1 - 1.8e-11 43.6 0.0 2.3e-11 43.3 0.0 1.1 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.6 KLO10907.1 - 1.9e-07 31.5 0.0 2.3e-07 31.3 0.0 1.2 1 0 0 1 1 1 1 Cyclin AAA PF00004.24 KLO10908.1 - 1e-92 307.2 0.0 1.8e-46 157.5 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 KLO10908.1 - 1.1e-12 47.5 0.0 3.8e-05 22.8 0.0 3.4 4 0 0 4 4 4 2 Holliday junction DNA helicase ruvB N-terminus AAA_2 PF07724.9 KLO10908.1 - 1.5e-11 44.5 0.0 1.2e-05 25.3 0.0 2.7 2 1 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_33 PF13671.1 KLO10908.1 - 8.1e-11 41.9 0.0 0.00036 20.4 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_5 PF07728.9 KLO10908.1 - 1.2e-10 41.1 0.3 0.00063 19.4 0.1 3.8 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_17 PF13207.1 KLO10908.1 - 9.2e-09 36.1 0.0 0.00063 20.5 0.0 2.9 2 1 0 2 2 2 2 AAA domain AAA_22 PF13401.1 KLO10908.1 - 9.9e-09 35.4 0.1 0.002 18.2 0.0 4.2 2 2 0 2 2 2 2 AAA domain AAA_25 PF13481.1 KLO10908.1 - 4.5e-08 32.7 0.8 0.014 14.8 0.0 3.4 2 2 1 3 3 3 2 AAA domain CDC48_N PF02359.13 KLO10908.1 - 6.7e-08 32.3 0.2 2.7e-07 30.4 0.1 2.2 2 0 0 2 2 1 1 Cell division protein 48 (CDC48), N-terminal domain TIP49 PF06068.8 KLO10908.1 - 1.2e-07 30.8 0.0 0.0048 15.6 0.0 2.7 2 0 0 2 2 2 2 TIP49 C-terminus AAA_16 PF13191.1 KLO10908.1 - 1.5e-07 31.5 0.0 0.0018 18.3 0.0 3.3 2 2 1 3 3 3 2 AAA ATPase domain IstB_IS21 PF01695.12 KLO10908.1 - 2.1e-06 27.2 0.0 0.0035 16.7 0.0 2.6 2 0 0 2 2 2 2 IstB-like ATP binding protein Mg_chelatase PF01078.16 KLO10908.1 - 7.2e-06 25.3 0.4 0.021 13.9 0.0 2.9 2 1 1 3 3 3 2 Magnesium chelatase, subunit ChlI KaiC PF06745.8 KLO10908.1 - 2e-05 23.8 0.3 0.15 11.1 0.0 3.4 2 1 1 3 3 3 1 KaiC AAA_19 PF13245.1 KLO10908.1 - 3.9e-05 23.3 0.3 0.0081 15.8 0.0 2.7 2 0 0 2 2 2 1 Part of AAA domain Zeta_toxin PF06414.7 KLO10908.1 - 5.9e-05 22.2 0.0 0.016 14.3 0.0 2.5 2 0 0 2 2 2 1 Zeta toxin AAA_14 PF13173.1 KLO10908.1 - 6.8e-05 22.7 0.0 0.15 11.9 0.0 2.7 2 0 0 2 2 2 2 AAA domain Sigma54_activ_2 PF14532.1 KLO10908.1 - 0.00016 21.7 0.0 0.97 9.4 0.0 2.8 3 0 0 3 3 2 2 Sigma-54 interaction domain RNA_helicase PF00910.17 KLO10908.1 - 0.00025 21.1 0.0 0.015 15.5 0.0 2.6 2 0 0 2 2 2 1 RNA helicase Parvo_NS1 PF01057.12 KLO10908.1 - 0.00051 19.0 0.1 0.0076 15.1 0.0 2.1 2 0 0 2 2 2 1 Parvovirus non-structural protein NS1 ResIII PF04851.10 KLO10908.1 - 0.0006 19.6 0.0 0.41 10.4 0.0 2.3 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit ABC_tran PF00005.22 KLO10908.1 - 0.00062 20.0 0.0 0.11 12.7 0.0 2.9 2 0 0 2 2 2 1 ABC transporter AAA_3 PF07726.6 KLO10908.1 - 0.00066 19.2 0.0 0.54 9.8 0.0 2.6 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 KLO10908.1 - 0.00076 18.9 0.0 0.35 10.3 0.0 3.1 2 1 0 2 2 2 1 Sigma-54 interaction domain CDC48_2 PF02933.12 KLO10908.1 - 0.001 18.6 0.0 0.0019 17.7 0.0 1.5 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), domain 2 Arch_ATPase PF01637.13 KLO10908.1 - 0.0011 18.6 0.0 1.3 8.7 0.0 2.5 2 0 0 2 2 2 2 Archaeal ATPase AAA_28 PF13521.1 KLO10908.1 - 0.0012 18.8 0.0 0.096 12.6 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 KLO10908.1 - 0.0018 18.5 0.0 0.03 14.6 0.0 2.4 2 0 0 2 2 2 1 AAA domain PhoH PF02562.11 KLO10908.1 - 0.0018 17.5 0.0 0.21 10.8 0.0 2.7 2 0 0 2 2 2 1 PhoH-like protein AAA_11 PF13086.1 KLO10908.1 - 0.0027 17.3 0.0 0.26 10.8 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_24 PF13479.1 KLO10908.1 - 0.003 17.1 0.0 0.1 12.1 0.0 3.0 3 0 0 3 3 3 1 AAA domain Bac_DnaA PF00308.13 KLO10908.1 - 0.0031 17.2 0.0 0.7 9.4 0.0 2.5 2 0 0 2 2 2 1 Bacterial dnaA protein DUF815 PF05673.8 KLO10908.1 - 0.0062 15.4 0.0 0.027 13.3 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF815) NACHT PF05729.7 KLO10908.1 - 0.011 15.3 0.0 0.46 10.1 0.0 3.0 3 0 0 3 3 3 0 NACHT domain Vps4_C PF09336.5 KLO10908.1 - 0.013 15.4 0.0 0.12 12.3 0.0 2.6 3 1 0 3 3 2 0 Vps4 C terminal oligomerisation domain NTPase_1 PF03266.10 KLO10908.1 - 0.019 14.6 0.3 1.1 8.9 0.0 2.8 3 0 0 3 3 2 0 NTPase DUF2075 PF09848.4 KLO10908.1 - 0.03 13.2 0.0 0.33 9.8 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) Viral_helicase1 PF01443.13 KLO10908.1 - 0.053 13.0 0.0 0.2 11.1 0.0 2.0 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase AAA_30 PF13604.1 KLO10908.1 - 0.068 12.7 0.0 0.97 8.9 0.0 2.5 2 0 0 2 2 2 0 AAA domain T2SE PF00437.15 KLO10908.1 - 0.071 11.9 0.0 0.23 10.3 0.0 1.9 2 0 0 2 2 1 0 Type II/IV secretion system protein NB-ARC PF00931.17 KLO10908.1 - 0.089 11.6 0.0 0.23 10.2 0.0 1.6 2 0 0 2 2 1 0 NB-ARC domain AAA_10 PF12846.2 KLO10908.1 - 0.12 11.8 0.0 4.6 6.5 0.0 3.0 3 0 0 3 3 3 0 AAA-like domain KAP_NTPase PF07693.9 KLO10908.1 - 0.13 11.2 0.0 1.5 7.7 0.0 2.3 2 1 0 2 2 2 0 KAP family P-loop domain Arrestin_N PF00339.24 KLO10909.1 - 0.014 15.2 0.4 0.06 13.1 0.3 1.9 1 1 0 1 1 1 0 Arrestin (or S-antigen), N-terminal domain Vps26 PF03643.10 KLO10909.1 - 0.21 10.3 0.0 0.37 9.5 0.0 1.4 1 0 0 1 1 1 0 Vacuolar protein sorting-associated protein 26 FAD-oxidase_C PF02913.14 KLO10910.1 - 2.2e-55 187.6 0.0 3.3e-55 187.1 0.0 1.2 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.18 KLO10910.1 - 4.1e-33 113.7 0.0 7.2e-33 112.9 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain eIF3_N PF09440.5 KLO10911.1 - 1.9e-39 134.8 5.3 4.7e-38 130.3 2.7 2.8 4 0 0 4 4 4 1 eIF3 subunit 6 N terminal domain PCI PF01399.22 KLO10911.1 - 1.8e-07 31.4 1.7 3.2e-07 30.6 0.1 2.1 2 0 0 2 2 2 1 PCI domain PCI_Csn8 PF10075.4 KLO10911.1 - 0.008 15.9 0.2 0.018 14.7 0.1 1.6 1 0 0 1 1 1 1 COP9 signalosome, subunit CSN8 DAHP_synth_2 PF01474.11 KLO10912.1 - 1.9e-180 599.9 0.0 2.2e-180 599.7 0.0 1.0 1 0 0 1 1 1 1 Class-II DAHP synthetase family UvdE PF03851.9 KLO10914.1 - 0.046 12.7 0.1 0.079 11.9 0.0 1.3 1 0 0 1 1 1 0 UV-endonuclease UvdE VPS11_C PF12451.3 KLO10914.1 - 0.28 11.0 5.6 2.6 7.9 0.1 3.4 4 0 0 4 4 4 0 Vacuolar protein sorting protein 11 C terminal PFEMP PF03011.10 KLO10914.1 - 0.36 11.1 4.3 1 9.6 0.2 2.6 2 0 0 2 2 2 0 PFEMP DBL domain Rabaptin PF03528.10 KLO10914.1 - 0.37 10.7 6.6 7.6 6.4 0.0 3.3 3 0 0 3 3 3 0 Rabaptin HECT PF00632.20 KLO10915.1 - 1.2e-93 313.7 0.0 1.8e-93 313.1 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) IQ PF00612.22 KLO10915.1 - 0.0028 17.1 2.1 0.003 17.0 0.3 2.0 2 0 0 2 2 2 1 IQ calmodulin-binding motif Pkinase PF00069.20 KLO10916.1 - 1.7e-28 99.5 0.0 2.1e-28 99.1 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KLO10916.1 - 2.5e-25 89.0 0.0 3.4e-25 88.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KLO10916.1 - 5.8e-05 22.2 0.0 7.1e-05 21.9 0.0 1.1 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 KLO10916.1 - 0.00011 22.0 0.0 0.0002 21.1 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.17 KLO10916.1 - 0.0012 18.2 0.0 0.002 17.4 0.0 1.3 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.9 KLO10916.1 - 0.012 14.7 0.0 0.017 14.1 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.6 KLO10916.1 - 0.082 11.7 0.1 0.19 10.5 0.1 1.5 2 0 0 2 2 2 0 Seadornavirus VP7 DUF692 PF05114.8 KLO10916.1 - 0.12 11.2 0.0 0.18 10.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF692) BNR PF02012.15 KLO10917.1 - 6.1e-11 40.4 32.0 0.13 12.1 0.0 9.3 10 0 0 10 10 10 6 BNR/Asp-box repeat Methyltransf_11 PF08241.7 KLO10918.1 - 9.8e-13 48.4 0.0 4e-12 46.4 0.0 2.2 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KLO10918.1 - 7.8e-12 45.2 0.0 1.8e-11 44.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KLO10918.1 - 1.7e-10 41.1 0.0 4.1e-10 39.9 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KLO10918.1 - 7.6e-10 39.3 0.0 3.5e-09 37.2 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 KLO10918.1 - 5.2e-09 36.1 0.0 1.4e-08 34.7 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KLO10918.1 - 2.3e-08 33.7 0.0 4.3e-08 32.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KLO10918.1 - 8.6e-08 31.5 0.0 1.4e-07 30.8 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.7 KLO10918.1 - 8.4e-07 29.3 0.0 2e-06 28.1 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.14 KLO10918.1 - 0.00014 21.8 0.0 0.00027 20.9 0.0 1.4 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_2 PF00891.13 KLO10918.1 - 0.00035 19.8 0.0 0.00059 19.1 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase MTS PF05175.9 KLO10918.1 - 0.0019 17.5 0.0 0.0037 16.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain MetW PF07021.7 KLO10918.1 - 0.0027 17.0 0.0 0.0049 16.2 0.0 1.3 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_4 PF02390.12 KLO10918.1 - 0.011 14.8 0.0 0.031 13.3 0.0 1.7 1 0 0 1 1 1 0 Putative methyltransferase CMAS PF02353.15 KLO10918.1 - 0.044 12.8 0.0 0.082 11.9 0.0 1.3 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase SRF-TF PF00319.13 KLO10919.1 - 9.8e-23 79.1 0.2 1.3e-22 78.7 0.1 1.2 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) F-box-like PF12937.2 KLO10921.1 - 8.9e-07 28.5 0.3 2.5e-06 27.1 0.2 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KLO10921.1 - 0.04 13.5 0.2 0.11 12.2 0.2 1.8 1 0 0 1 1 1 0 F-box domain Abhydrolase_4 PF08386.5 KLO10922.1 - 8.2e-25 86.6 0.0 1.6e-24 85.7 0.0 1.4 1 0 0 1 1 1 1 TAP-like protein Abhydrolase_1 PF00561.15 KLO10922.1 - 9e-20 71.2 0.0 2.9e-17 62.9 0.0 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 KLO10922.1 - 7.9e-13 48.8 0.0 1.6e-12 47.7 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KLO10922.1 - 4.8e-05 23.1 0.0 0.16 11.6 0.0 2.3 2 0 0 2 2 2 2 Alpha/beta hydrolase family PIF1 PF05970.9 KLO10923.1 - 4.1e-59 200.3 0.8 2.6e-56 191.1 0.6 2.1 1 1 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.1 KLO10923.1 - 3.6e-17 62.5 0.0 6.8e-17 61.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain Herpes_Helicase PF02689.9 KLO10923.1 - 2.3e-09 35.5 0.5 3e-08 31.9 0.0 2.2 2 0 0 2 2 2 1 Helicase AAA_22 PF13401.1 KLO10923.1 - 4.2e-08 33.4 0.0 9.2e-08 32.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.13 KLO10923.1 - 3.4e-07 30.0 0.6 0.0055 16.2 0.1 3.9 3 1 0 3 3 3 2 Viral (Superfamily 1) RNA helicase AAA_19 PF13245.1 KLO10923.1 - 4.3e-06 26.3 0.1 1.2e-05 24.9 0.1 1.8 1 0 0 1 1 1 1 Part of AAA domain UvrD_C_2 PF13538.1 KLO10923.1 - 2.4e-05 24.3 0.0 5.5e-05 23.2 0.0 1.6 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA_16 PF13191.1 KLO10923.1 - 0.00019 21.4 0.0 0.00039 20.4 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain IstB_IS21 PF01695.12 KLO10923.1 - 0.00035 20.0 0.0 0.38 10.1 0.0 2.3 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_14 PF13173.1 KLO10923.1 - 0.0005 19.9 0.1 0.0053 16.6 0.0 2.3 1 1 0 1 1 1 1 AAA domain PhoH PF02562.11 KLO10923.1 - 0.0023 17.1 0.0 0.01 15.1 0.0 2.1 2 0 0 2 2 2 1 PhoH-like protein DUF2075 PF09848.4 KLO10923.1 - 0.0039 16.2 0.0 0.3 10.0 0.0 2.8 2 1 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) AAA_17 PF13207.1 KLO10923.1 - 0.0097 16.7 0.0 0.023 15.5 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.9 KLO10923.1 - 0.011 15.4 0.0 2.3 7.9 0.0 2.6 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) ABC_tran PF00005.22 KLO10923.1 - 0.012 15.9 0.1 0.22 11.8 0.1 2.7 1 1 0 1 1 1 0 ABC transporter AAA_10 PF12846.2 KLO10923.1 - 0.016 14.6 0.0 0.031 13.7 0.0 1.4 1 0 0 1 1 1 0 AAA-like domain NTPase_1 PF03266.10 KLO10923.1 - 0.017 14.8 0.0 0.24 11.0 0.0 2.3 2 0 0 2 2 2 0 NTPase AAA PF00004.24 KLO10923.1 - 0.018 15.2 0.1 0.049 13.8 0.1 1.8 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_32 PF13654.1 KLO10923.1 - 0.028 13.0 0.0 0.093 11.3 0.0 1.7 2 0 0 2 2 2 0 AAA domain DEAD PF00270.24 KLO10923.1 - 0.031 13.7 0.0 1.7 8.0 0.0 2.4 1 1 1 2 2 2 0 DEAD/DEAH box helicase Arch_ATPase PF01637.13 KLO10923.1 - 0.031 13.9 0.0 0.71 9.5 0.0 2.3 2 0 0 2 2 2 0 Archaeal ATPase NACHT PF05729.7 KLO10923.1 - 0.032 13.8 0.0 0.062 12.9 0.0 1.5 1 0 0 1 1 1 0 NACHT domain AAA_11 PF13086.1 KLO10923.1 - 0.043 13.3 0.1 2.2 7.8 0.0 2.5 1 1 1 2 2 2 0 AAA domain AAA_33 PF13671.1 KLO10923.1 - 0.059 13.2 0.0 0.13 12.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain ArgK PF03308.11 KLO10923.1 - 0.065 11.9 0.0 0.12 11.1 0.0 1.4 1 0 0 1 1 1 0 ArgK protein VGCC_alpha2 PF08473.6 KLO10925.1 - 0.03 14.0 0.1 0.066 12.9 0.0 1.5 1 0 0 1 1 1 0 Neuronal voltage-dependent calcium channel alpha 2acd F-box-like PF12937.2 KLO10925.1 - 0.12 12.1 0.0 0.91 9.3 0.0 2.3 2 0 0 2 2 2 0 F-box-like Retrotrans_gag PF03732.12 KLO10931.1 - 2.1e-06 27.7 0.7 5e-06 26.4 0.5 1.6 1 0 0 1 1 1 1 Retrotransposon gag protein Optomotor-blind PF11078.3 KLO10933.1 - 0.045 14.1 4.5 0.052 13.8 3.1 1.1 1 0 0 1 1 1 0 Optomotor-blind protein N-terminal region PIF1 PF05970.9 KLO10934.1 - 1.3e-12 47.3 0.0 1.8e-12 46.9 0.0 1.3 1 1 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.1 KLO10934.1 - 3.8e-07 29.8 0.0 5.7e-07 29.2 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 KLO10934.1 - 0.00042 20.0 0.0 0.00069 19.3 0.0 1.3 1 0 0 1 1 1 1 Part of AAA domain AAA_5 PF07728.9 KLO10934.1 - 0.0069 16.1 0.0 0.014 15.1 0.0 1.6 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.12 KLO10934.1 - 0.011 15.2 0.2 0.032 13.6 0.1 2.0 1 1 1 2 2 2 0 IstB-like ATP binding protein Bac_DnaA PF00308.13 KLO10934.1 - 0.019 14.6 0.3 0.37 10.3 0.0 2.5 1 1 1 2 2 2 0 Bacterial dnaA protein AAA PF00004.24 KLO10934.1 - 0.028 14.6 0.1 0.064 13.4 0.1 1.6 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Mg_chelatase PF01078.16 KLO10934.1 - 0.028 13.5 0.3 0.05 12.7 0.0 1.6 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_22 PF13401.1 KLO10934.1 - 0.038 14.1 0.1 0.1 12.7 0.1 1.8 1 1 0 1 1 1 0 AAA domain SPAN-X PF07458.7 KLO10934.1 - 0.051 13.7 0.3 0.089 13.0 0.2 1.3 1 0 0 1 1 1 0 Sperm protein associated with nucleus, mapped to X chromosome AAA_16 PF13191.1 KLO10934.1 - 0.092 12.7 0.0 0.13 12.1 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain AFG1_ATPase PF03969.11 KLO10934.1 - 0.12 11.1 0.0 0.15 10.8 0.0 1.1 1 0 0 1 1 1 0 AFG1-like ATPase Helitron_like_N PF14214.1 KLO10936.1 - 3e-05 23.8 0.0 3.8e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus HNH PF01844.18 KLO10937.1 - 0.083 12.7 0.1 0.15 11.9 0.1 1.5 1 0 0 1 1 1 0 HNH endonuclease F-box PF00646.28 KLO10938.1 - 1.5e-05 24.5 0.8 3.9e-05 23.1 0.0 2.1 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.2 KLO10938.1 - 4.9e-05 22.9 0.0 0.00013 21.6 0.0 1.8 1 0 0 1 1 1 1 F-box-like MFS_1 PF07690.11 KLO10939.1 - 5e-24 84.6 42.0 3.5e-16 58.8 2.8 2.8 2 1 1 3 3 3 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KLO10939.1 - 3.1e-18 65.5 0.1 3.1e-18 65.5 0.1 2.8 2 1 1 3 3 3 2 Sugar (and other) transporter FB_lectin PF07367.6 KLO10940.1 - 8.4e-55 184.2 0.8 9.5e-55 184.0 0.6 1.0 1 0 0 1 1 1 1 Fungal fruit body lectin ABC2_membrane PF01061.19 KLO10942.1 - 2.1e-32 111.9 17.3 2.1e-32 111.9 12.0 2.1 2 0 0 2 2 2 1 ABC-2 type transporter ABC_tran PF00005.22 KLO10942.1 - 8.9e-22 77.8 0.1 1.4e-21 77.2 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 KLO10942.1 - 2.3e-08 34.3 0.0 2.4e-06 27.7 0.0 2.3 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 KLO10942.1 - 0.0023 17.9 0.0 0.0038 17.2 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain ABC2_membrane_3 PF12698.2 KLO10942.1 - 0.0067 15.5 22.4 0.016 14.2 15.3 1.7 1 1 0 1 1 1 1 ABC-2 family transporter protein AAA PF00004.24 KLO10942.1 - 0.01 16.0 0.1 0.14 12.3 0.1 2.3 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) SbcCD_C PF13558.1 KLO10942.1 - 0.016 15.1 0.0 0.046 13.6 0.0 1.8 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_22 PF13401.1 KLO10942.1 - 0.03 14.4 0.1 0.097 12.8 0.1 1.8 1 1 0 1 1 1 0 AAA domain AAA_29 PF13555.1 KLO10942.1 - 0.03 13.8 0.2 0.079 12.4 0.1 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_17 PF13207.1 KLO10942.1 - 0.035 14.9 0.0 0.067 14.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_15 PF13175.1 KLO10942.1 - 0.054 12.5 0.1 1.4 7.8 0.1 2.1 2 0 0 2 2 2 0 AAA ATPase domain DUF258 PF03193.11 KLO10942.1 - 0.11 11.7 0.0 0.17 11.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_18 PF13238.1 KLO10942.1 - 0.11 12.7 0.0 0.23 11.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain SMC_N PF02463.14 KLO10942.1 - 0.2 10.8 0.3 0.73 9.0 0.2 1.8 1 1 0 1 1 1 0 RecF/RecN/SMC N terminal domain Asp PF00026.18 KLO10943.1 - 2.9e-08 33.3 0.2 0.0011 18.2 0.0 2.4 2 1 0 2 2 2 2 Eukaryotic aspartyl protease Asp_protease_2 PF13650.1 KLO10943.1 - 0.0001 22.7 1.5 0.00057 20.3 0.5 2.7 3 0 0 3 3 3 1 Aspartyl protease gag-asp_proteas PF13975.1 KLO10943.1 - 0.0043 16.8 0.0 0.013 15.2 0.0 1.8 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease TMEM154 PF15102.1 KLO10943.1 - 0.055 13.1 0.0 0.09 12.4 0.0 1.2 1 0 0 1 1 1 0 TMEM154 protein family DUF912 PF06024.7 KLO10943.1 - 0.11 12.5 0.0 0.18 11.8 0.0 1.3 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Rifin_STEVOR PF02009.11 KLO10943.1 - 0.23 11.0 0.0 0.32 10.5 0.0 1.1 1 0 0 1 1 1 0 Rifin/stevor family BTB PF00651.26 KLO10944.1 - 6e-09 35.8 0.0 6.1e-08 32.6 0.0 2.2 2 1 1 3 3 3 1 BTB/POZ domain BTB PF00651.26 KLO10948.1 - 2.1e-05 24.4 0.0 5.6e-05 23.0 0.0 1.7 1 0 0 1 1 1 1 BTB/POZ domain BTB PF00651.26 KLO10949.1 - 2.6e-09 37.0 0.0 8e-09 35.4 0.0 1.8 2 0 0 2 2 2 1 BTB/POZ domain zf-C2H2_4 PF13894.1 KLO10950.1 - 0.00079 19.5 16.4 0.17 12.3 0.3 3.4 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2 PF00096.21 KLO10950.1 - 0.11 12.9 13.8 0.73 10.2 0.3 3.4 3 0 0 3 3 3 0 Zinc finger, C2H2 type WD40 PF00400.27 KLO10951.1 - 3.6e-53 175.6 24.0 4.7e-11 42.1 0.1 8.5 9 0 0 9 9 9 7 WD domain, G-beta repeat F-box-like PF12937.2 KLO10951.1 - 1.7e-06 27.6 0.2 1.7e-06 27.6 0.1 2.3 2 0 0 2 2 2 1 F-box-like Nup160 PF11715.3 KLO10951.1 - 4e-05 21.9 6.6 0.17 10.0 0.0 4.8 2 1 4 6 6 6 3 Nucleoporin Nup120/160 F-box PF00646.28 KLO10951.1 - 0.0062 16.1 0.4 0.016 14.8 0.3 1.8 1 0 0 1 1 1 1 F-box domain Nucleoporin_N PF08801.6 KLO10951.1 - 0.12 11.0 0.0 0.61 8.7 0.0 1.9 2 0 0 2 2 2 0 Nup133 N terminal like RMP PF14996.1 KLO10952.1 - 0.0011 18.9 0.0 0.0013 18.6 0.0 1.2 1 0 0 1 1 1 1 Retinal Maintenance PEMT PF04191.8 KLO10953.1 - 1.9e-08 34.3 1.6 4.9e-08 33.0 0.0 2.1 2 0 0 2 2 2 1 Phospholipid methyltransferase ICMT PF04140.9 KLO10953.1 - 3.1e-06 27.2 0.0 5.4e-06 26.5 0.0 1.4 1 0 0 1 1 1 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family ERG4_ERG24 PF01222.12 KLO10953.1 - 0.035 12.6 0.0 0.05 12.1 0.0 1.2 1 0 0 1 1 1 0 Ergosterol biosynthesis ERG4/ERG24 family zf-MYND PF01753.13 KLO10954.1 - 3.7e-10 39.4 12.6 6.9e-10 38.6 8.7 1.5 1 0 0 1 1 1 1 MYND finger zf-Mss51 PF13824.1 KLO10954.1 - 0.79 9.6 5.2 2 8.3 3.6 1.7 1 0 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 BTB PF00651.26 KLO10955.1 - 1.8e-09 37.5 0.0 3.4e-09 36.6 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain zf-C2H2_4 PF13894.1 KLO10955.1 - 0.15 12.4 1.4 0.43 11.0 0.0 2.3 2 0 0 2 2 2 0 C2H2-type zinc finger BTB PF00651.26 KLO10956.1 - 1.3e-07 31.5 0.0 3e-07 30.3 0.0 1.6 1 0 0 1 1 1 1 BTB/POZ domain Curto_V2 PF07325.6 KLO10957.1 - 0.049 13.2 1.1 0.087 12.4 0.2 1.7 2 0 0 2 2 2 0 Curtovirus V2 protein Thioredoxin_8 PF13905.1 KLO10957.1 - 0.071 13.2 0.0 0.12 12.5 0.0 1.5 1 0 0 1 1 1 0 Thioredoxin-like WD40 PF00400.27 KLO10958.1 - 8.6e-125 402.7 50.7 6.5e-12 44.8 0.0 14.8 14 0 0 14 14 14 14 WD domain, G-beta repeat eIF2A PF08662.6 KLO10958.1 - 4.3e-12 46.1 0.0 0.039 13.6 0.0 4.4 2 1 1 4 4 4 3 Eukaryotic translation initiation factor eIF2A NACHT PF05729.7 KLO10958.1 - 5.2e-07 29.4 0.2 5.1e-06 26.2 0.1 2.2 1 1 0 1 1 1 1 NACHT domain DUF3312 PF11768.3 KLO10958.1 - 1.1e-05 23.9 0.2 0.93 7.6 0.1 4.6 3 1 2 5 5 5 2 Protein of unknown function (DUF3312) AAA PF00004.24 KLO10958.1 - 0.00088 19.4 0.0 0.003 17.7 0.0 1.9 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Nucleoporin_N PF08801.6 KLO10958.1 - 0.0019 17.0 5.7 2.8 6.5 0.1 5.7 1 1 4 5 5 5 1 Nup133 N terminal like AAA_16 PF13191.1 KLO10958.1 - 0.0024 17.8 0.0 0.0088 16.0 0.0 1.9 1 1 0 1 1 1 1 AAA ATPase domain Nbas_N PF15492.1 KLO10958.1 - 0.0033 16.5 2.5 0.05 12.6 0.0 3.9 4 1 1 5 5 5 1 Neuroblastoma-amplified sequence, N terminal AAA_22 PF13401.1 KLO10958.1 - 0.036 14.2 0.0 0.41 10.7 0.0 2.7 2 1 0 2 2 2 0 AAA domain AAA_19 PF13245.1 KLO10958.1 - 0.087 12.5 0.0 0.25 11.1 0.0 1.8 1 0 0 1 1 1 0 Part of AAA domain Cu-oxidase PF00394.17 KLO10959.1 - 1.4e-51 174.5 0.1 2.1e-45 154.4 0.0 2.9 3 0 0 3 3 3 2 Multicopper oxidase Cu-oxidase_2 PF07731.9 KLO10959.1 - 2.3e-35 121.1 6.8 8.1e-35 119.3 0.0 3.5 3 1 0 3 3 3 1 Multicopper oxidase Cu-oxidase_3 PF07732.10 KLO10959.1 - 2.4e-34 117.5 2.4 1.5e-31 108.6 0.1 3.7 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase PF00394.17 KLO10961.1 - 1.4e-53 181.0 1.4 1.4e-47 161.5 0.1 3.0 3 0 0 3 3 3 2 Multicopper oxidase Cu-oxidase_2 PF07731.9 KLO10961.1 - 1.9e-35 121.3 8.8 2e-34 118.0 0.1 3.7 3 2 0 3 3 3 2 Multicopper oxidase Cu-oxidase_3 PF07732.10 KLO10961.1 - 1.6e-32 111.7 3.1 3.6e-31 107.3 0.3 3.2 3 0 0 3 3 3 1 Multicopper oxidase DDE_Tnp_IS1 PF03400.8 KLO10964.1 - 0.079 13.0 0.2 0.17 11.9 0.1 1.6 2 0 0 2 2 2 0 IS1 transposase GMC_oxred_N PF00732.14 KLO10967.1 - 8.6e-71 238.5 0.0 1.1e-70 238.1 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 KLO10967.1 - 1.4e-36 125.9 0.0 2.5e-36 125.1 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 KLO10967.1 - 1.8e-06 27.1 0.0 9.3e-05 21.4 0.0 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 KLO10967.1 - 6e-05 22.0 0.4 0.0025 16.7 0.2 2.2 2 0 0 2 2 2 1 FAD binding domain Lycopene_cycl PF05834.7 KLO10967.1 - 0.0001 21.3 0.2 0.00015 20.8 0.1 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_8 PF13450.1 KLO10967.1 - 0.00093 19.1 0.1 0.0024 17.8 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 KLO10967.1 - 0.003 17.4 0.0 0.01 15.7 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 KLO10967.1 - 0.0036 17.3 0.1 2.8 7.9 0.0 2.6 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 KLO10967.1 - 0.017 14.9 0.2 1.1 8.9 0.1 2.4 1 1 0 1 1 1 0 FAD-NAD(P)-binding HI0933_like PF03486.9 KLO10967.1 - 0.032 12.7 0.1 0.055 11.9 0.0 1.3 1 0 0 1 1 1 0 HI0933-like protein Thi4 PF01946.12 KLO10967.1 - 0.039 13.0 0.1 0.075 12.1 0.0 1.4 1 0 0 1 1 1 0 Thi4 family Pyr_redox PF00070.22 KLO10967.1 - 0.04 14.3 0.0 0.1 12.9 0.0 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 KLO10967.1 - 0.062 11.9 0.1 0.099 11.2 0.0 1.3 1 0 0 1 1 1 0 Tryptophan halogenase DPPIV_N PF00930.16 KLO10968.1 - 1.5e-84 283.5 0.0 2.1e-84 283.1 0.0 1.2 1 0 0 1 1 1 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Peptidase_S9 PF00326.16 KLO10968.1 - 6.3e-42 143.2 0.7 1e-41 142.5 0.5 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 KLO10968.1 - 3.8e-08 33.1 0.1 8.3e-08 32.1 0.1 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S15 PF02129.13 KLO10968.1 - 8.1e-05 22.1 1.1 0.00029 20.3 0.5 1.9 1 1 1 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_2 PF02230.11 KLO10968.1 - 0.17 11.3 0.0 1.7 8.0 0.0 2.1 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Mito_carr PF00153.22 KLO10969.1 - 2.8e-62 206.4 0.8 2.8e-22 78.2 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein F-box-like PF12937.2 KLO10970.1 - 4.8e-08 32.5 1.4 9.1e-08 31.7 0.2 2.2 2 0 0 2 2 2 1 F-box-like LRR_8 PF13855.1 KLO10970.1 - 0.01 15.5 6.2 0.78 9.5 0.0 4.1 4 2 0 4 4 4 0 Leucine rich repeat DUF1019 PF06254.6 KLO10970.1 - 0.095 12.8 0.0 0.19 11.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1019) SYS1 PF09801.4 KLO10971.1 - 8.8e-29 100.3 1.0 1.3e-20 73.8 0.8 2.1 2 0 0 2 2 2 2 Integral membrane protein S linking to the trans Golgi network CopD PF05425.8 KLO10974.1 - 0.0041 17.3 0.8 0.0083 16.3 0.6 1.5 1 0 0 1 1 1 1 Copper resistance protein D BCS1_N PF08740.6 KLO10975.1 - 2e-29 102.5 2.4 2e-29 102.5 1.7 2.3 2 0 0 2 2 2 1 BCS1 N terminal AAA PF00004.24 KLO10975.1 - 1.1e-14 54.7 0.0 3.7e-13 49.8 0.0 2.5 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 KLO10975.1 - 0.00025 21.0 0.0 0.00083 19.3 0.0 1.9 1 0 0 1 1 1 1 AAA ATPase domain AAA_33 PF13671.1 KLO10975.1 - 0.00058 19.7 0.6 0.002 18.0 0.4 2.0 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 KLO10975.1 - 0.0076 17.0 0.0 0.0076 17.0 0.0 3.1 2 1 0 2 2 1 1 AAA domain Viral_helicase1 PF01443.13 KLO10975.1 - 0.0094 15.4 0.0 0.0094 15.4 0.0 1.8 2 0 0 2 2 1 1 Viral (Superfamily 1) RNA helicase AAA_23 PF13476.1 KLO10975.1 - 0.014 15.7 17.1 0.14 12.4 10.6 2.4 2 0 0 2 2 2 0 AAA domain RuvB_N PF05496.7 KLO10975.1 - 0.045 12.8 0.0 0.081 11.9 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus NACHT PF05729.7 KLO10975.1 - 0.071 12.7 0.2 0.34 10.5 0.0 2.2 3 0 0 3 3 3 0 NACHT domain DUF3439 PF11921.3 KLO10975.1 - 0.081 12.6 5.1 0.25 11.0 3.5 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) AAA_22 PF13401.1 KLO10975.1 - 0.091 12.9 0.1 0.28 11.3 0.0 1.8 2 0 0 2 2 1 0 AAA domain DDRGK PF09756.4 KLO10975.1 - 0.1 12.0 36.2 49 3.2 28.4 2.5 2 0 0 2 2 2 0 DDRGK domain AAA_19 PF13245.1 KLO10975.1 - 0.1 12.3 1.2 0.34 10.6 0.0 2.4 3 0 0 3 3 3 0 Part of AAA domain AAA_3 PF07726.6 KLO10975.1 - 0.16 11.5 0.0 0.3 10.6 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) MAP7 PF05672.6 KLO10975.1 - 0.4 10.0 46.3 0.01 15.2 26.2 2.2 2 0 0 2 2 2 0 MAP7 (E-MAP-115) family Ycf1 PF05758.7 KLO10975.1 - 0.79 7.3 19.9 1.1 6.8 13.8 1.2 1 0 0 1 1 1 0 Ycf1 GAGA_bind PF06217.7 KLO10975.1 - 2.8 7.8 18.3 5.6 6.8 12.7 1.5 1 0 0 1 1 1 0 GAGA binding protein-like family Neur_chan_memb PF02932.11 KLO10975.1 - 3.8 7.3 11.8 8.8 6.1 8.2 1.6 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region RRN3 PF05327.6 KLO10975.1 - 5.6 4.9 10.8 10 4.1 7.5 1.4 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 DUF4551 PF15087.1 KLO10975.1 - 6.2 5.0 19.8 10 4.3 13.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Dynamin_M PF01031.15 KLO10976.1 - 2.3e-113 377.8 0.0 4.9e-113 376.8 0.0 1.5 1 0 0 1 1 1 1 Dynamin central region Dynamin_N PF00350.18 KLO10976.1 - 8.5e-57 191.6 0.0 1.7e-56 190.6 0.0 1.5 1 0 0 1 1 1 1 Dynamin family GED PF02212.13 KLO10976.1 - 1.4e-30 105.0 2.0 2.4e-29 101.0 0.8 2.5 2 0 0 2 2 2 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.18 KLO10976.1 - 0.00032 20.6 0.1 0.0014 18.5 0.0 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase Condensin2nSMC PF12422.3 KLO10976.1 - 0.003 17.3 0.1 0.0087 15.8 0.1 1.8 1 0 0 1 1 1 1 Condensin II non structural maintenance of chromosomes subunit AAA_16 PF13191.1 KLO10976.1 - 0.0072 16.3 0.0 0.021 14.7 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain Miro PF08477.8 KLO10976.1 - 0.029 14.8 0.0 0.069 13.6 0.0 1.7 1 0 0 1 1 1 0 Miro-like protein DUF605 PF04652.11 KLO10976.1 - 0.16 11.3 4.7 0.24 10.7 3.3 1.2 1 0 0 1 1 1 0 Vta1 like LRR_6 PF13516.1 KLO10977.1 - 0.13 12.3 3.5 17 5.8 0.0 5.1 7 0 0 7 7 7 0 Leucine Rich repeat Phage_int_SAM_1 PF02899.12 KLO10977.1 - 0.23 11.6 1.6 2.1 8.5 0.0 2.9 3 0 0 3 3 3 0 Phage integrase, N-terminal SAM-like domain SE PF08491.5 KLO10978.1 - 1.1e-89 299.9 0.0 1.4e-89 299.5 0.0 1.1 1 0 0 1 1 1 1 Squalene epoxidase DAO PF01266.19 KLO10978.1 - 6.5e-09 35.1 0.0 0.00083 18.3 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 KLO10978.1 - 2.6e-07 30.0 0.3 0.042 12.8 0.1 3.1 3 0 0 3 3 3 3 FAD binding domain FAD_binding_2 PF00890.19 KLO10978.1 - 0.0004 19.3 4.3 0.37 9.5 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain Lycopene_cycl PF05834.7 KLO10978.1 - 0.00067 18.6 0.2 0.022 13.7 0.1 2.3 3 0 0 3 3 3 1 Lycopene cyclase protein GIDA PF01134.17 KLO10978.1 - 0.0026 16.6 0.8 0.71 8.6 0.0 2.1 2 0 0 2 2 2 2 Glucose inhibited division protein A Trp_halogenase PF04820.9 KLO10978.1 - 0.008 14.8 0.3 1.6 7.2 0.0 2.2 2 0 0 2 2 2 2 Tryptophan halogenase NAD_binding_8 PF13450.1 KLO10978.1 - 0.0085 16.1 0.1 0.022 14.8 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain GMC_oxred_N PF00732.14 KLO10978.1 - 0.0094 15.1 0.3 0.65 9.1 0.0 2.3 2 0 0 2 2 2 1 GMC oxidoreductase NAD_binding_9 PF13454.1 KLO10978.1 - 0.12 12.0 0.1 0.47 10.2 0.0 1.9 2 0 0 2 2 2 0 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 KLO10978.1 - 0.18 11.6 0.7 0.35 10.7 0.5 1.7 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase CoA_binding_2 PF13380.1 KLO10979.1 - 0.13 12.3 0.1 0.39 10.9 0.1 1.8 1 1 0 1 1 1 0 CoA binding domain Cu-oxidase PF00394.17 KLO10980.1 - 1.7e-50 171.0 0.0 2.5e-47 160.7 0.0 2.6 2 0 0 2 2 2 2 Multicopper oxidase Cu-oxidase_3 PF07732.10 KLO10980.1 - 2.8e-38 130.2 0.0 5.1e-35 119.7 0.0 3.5 3 0 0 3 3 3 1 Multicopper oxidase Cu-oxidase_2 PF07731.9 KLO10980.1 - 3.2e-38 130.3 1.9 2.3e-35 121.1 0.0 3.7 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase PF00394.17 KLO10981.1 - 7.1e-52 175.5 0.1 6.3e-48 162.6 0.0 2.6 2 0 0 2 2 2 2 Multicopper oxidase Cu-oxidase_3 PF07732.10 KLO10981.1 - 2.8e-39 133.5 0.0 4.4e-35 119.9 0.0 3.6 3 0 0 3 3 3 3 Multicopper oxidase Cu-oxidase_2 PF07731.9 KLO10981.1 - 4.8e-39 133.0 4.3 1.3e-36 125.1 0.0 3.8 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase PF00394.17 KLO10982.1 - 3.3e-52 176.6 3.3 1.3e-47 161.6 0.2 3.4 4 0 0 4 4 4 2 Multicopper oxidase Cu-oxidase_2 PF07731.9 KLO10982.1 - 1e-40 138.4 1.7 5.7e-37 126.3 0.0 3.9 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase_3 PF07732.10 KLO10982.1 - 3.6e-38 129.9 0.3 1.6e-35 121.3 0.0 3.3 3 0 0 3 3 3 1 Multicopper oxidase Methyltransf_16 PF10294.4 KLO10983.1 - 1.9e-16 60.0 0.0 2.8e-16 59.4 0.0 1.2 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_18 PF12847.2 KLO10983.1 - 0.00076 20.0 0.0 0.0014 19.2 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain GidB PF02527.10 KLO10983.1 - 0.013 14.6 0.0 0.025 13.7 0.0 1.4 1 0 0 1 1 1 0 rRNA small subunit methyltransferase G MTS PF05175.9 KLO10983.1 - 0.017 14.5 0.0 0.077 12.3 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase small domain Methyltransf_12 PF08242.7 KLO10983.1 - 0.052 14.0 0.0 0.099 13.1 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.1 KLO10983.1 - 0.15 11.6 0.0 0.53 9.8 0.0 1.9 1 1 0 1 1 1 0 Methyltransferase domain PQQ PF01011.16 KLO10986.1 - 5.8e-05 22.4 0.0 0.0019 17.6 0.0 2.7 3 0 0 3 3 3 1 PQQ enzyme repeat PQQ_2 PF13360.1 KLO10986.1 - 0.027 13.9 0.0 0.13 11.6 0.0 1.9 1 1 1 2 2 2 0 PQQ-like domain Nucleoporin_N PF08801.6 KLO10986.1 - 0.076 11.7 0.0 0.13 10.9 0.0 1.3 1 0 0 1 1 1 0 Nup133 N terminal like CAP_N PF01213.14 KLO10987.1 - 0.24 10.6 17.9 0.022 14.0 1.6 2.2 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal Pro-rich_19 PF15455.1 KLO10991.1 - 0.0076 15.3 1.8 0.008 15.2 1.2 1.0 1 0 0 1 1 1 1 Proline-rich 19 DUF4169 PF13770.1 KLO10991.1 - 0.035 14.0 4.8 0.6 10.0 0.3 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4169) BTB PF00651.26 KLO10992.1 - 1.6e-06 28.0 0.1 3.3e-06 27.0 0.1 1.6 1 1 0 1 1 1 1 BTB/POZ domain BTB PF00651.26 KLO10993.1 - 2.8e-07 30.5 0.0 8.2e-07 28.9 0.0 1.8 1 0 0 1 1 1 1 BTB/POZ domain Pkinase_Tyr PF07714.12 KLO10994.1 - 6.9e-17 61.3 0.0 1e-16 60.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 KLO10994.1 - 5.2e-15 55.2 0.0 8.5e-15 54.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KLO10995.1 - 0.0045 16.0 0.0 0.0045 16.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 KLO10996.1 - 3.4e-35 121.4 0.0 4e-35 121.2 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KLO10996.1 - 1.8e-32 112.4 0.0 2.3e-32 112.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KLO10996.1 - 0.0018 17.2 0.0 0.0025 16.8 0.0 1.1 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.17 KLO10996.1 - 0.032 13.5 0.0 0.048 12.9 0.0 1.2 1 0 0 1 1 1 0 RIO1 family APH PF01636.18 KLO10996.1 - 0.14 11.8 0.1 0.26 11.0 0.0 1.4 2 0 0 2 2 2 0 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.6 KLO10996.1 - 0.16 10.7 0.1 0.2 10.3 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase He_PIG PF05345.7 KLO10996.1 - 0.17 11.9 1.9 0.43 10.6 1.3 1.6 1 0 0 1 1 1 0 Putative Ig domain Pkinase PF00069.20 KLO10997.1 - 8.3e-26 90.6 0.0 1.3e-25 90.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KLO10997.1 - 2.8e-25 88.8 0.0 4.2e-25 88.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 KLO10997.1 - 0.059 13.1 0.1 0.68 9.6 0.0 2.4 2 0 0 2 2 2 0 Phosphotransferase enzyme family BTB PF00651.26 KLO10998.1 - 1.4e-07 31.4 0.0 3e-07 30.4 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain Pkinase_Tyr PF07714.12 KLO10999.1 - 2.7e-32 111.8 0.0 4.6e-32 111.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 KLO10999.1 - 5.9e-30 104.2 0.0 1.1e-29 103.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Sec34 PF04136.10 KLO10999.1 - 0.11 12.2 2.0 0.21 11.2 1.4 1.4 1 0 0 1 1 1 0 Sec34-like family Pkinase PF00069.20 KLO11000.1 - 3.2e-27 95.3 0.0 3.5e-27 95.1 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KLO11000.1 - 5.2e-24 84.7 0.0 6e-24 84.5 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.17 KLO11000.1 - 0.064 12.6 0.0 0.091 12.1 0.0 1.2 1 0 0 1 1 1 0 RIO1 family APH PF01636.18 KLO11000.1 - 0.099 12.3 0.0 0.11 12.1 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pkinase PF00069.20 KLO11001.1 - 1.1e-27 96.8 0.0 2.4e-27 95.7 0.0 1.5 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 KLO11001.1 - 1.1e-25 90.1 0.0 1.7e-25 89.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Taxilin PF09728.4 KLO11001.1 - 0.052 12.6 0.5 0.096 11.7 0.4 1.3 1 0 0 1 1 1 0 Myosin-like coiled-coil protein Pkinase_Tyr PF07714.12 KLO11005.1 - 3.8e-28 98.2 0.0 6.4e-28 97.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 KLO11005.1 - 5e-28 97.9 0.0 9.3e-28 97.0 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain DUF869 PF05911.6 KLO11005.1 - 0.079 11.1 1.4 0.073 11.3 0.2 1.4 1 1 0 1 1 1 0 Plant protein of unknown function (DUF869) Pkinase PF00069.20 KLO11006.1 - 7.7e-37 126.8 0.0 8.9e-37 126.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KLO11006.1 - 3.9e-28 98.2 0.0 4.5e-28 98.0 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KLO11006.1 - 9e-07 28.1 0.0 1.2e-06 27.7 0.0 1.1 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.17 KLO11006.1 - 0.0039 16.5 0.0 0.0053 16.1 0.0 1.2 1 0 0 1 1 1 1 RIO1 family APH PF01636.18 KLO11006.1 - 0.033 13.9 0.0 0.045 13.4 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.9 KLO11006.1 - 0.15 11.1 0.1 0.3 10.1 0.0 1.6 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_Tyr PF07714.12 KLO11007.1 - 6.1e-52 176.2 0.0 2.6e-26 92.2 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.20 KLO11007.1 - 2.2e-45 154.8 0.0 2.2e-22 79.4 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain MetW PF07021.7 KLO11012.1 - 0.1 11.9 0.0 0.17 11.2 0.0 1.3 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Pkinase PF00069.20 KLO11013.1 - 9e-31 106.9 0.0 9.9e-31 106.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KLO11013.1 - 6.1e-29 100.8 0.0 7.7e-29 100.5 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_Tyr PF07714.12 KLO11014.1 - 0.11 11.5 0.0 0.15 11.0 0.0 1.2 1 0 0 1 1 1 0 Protein tyrosine kinase AAA_22 PF13401.1 KLO11018.1 - 2.9e-09 37.1 0.0 6.8e-09 35.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 KLO11018.1 - 1.3e-07 31.7 0.0 4.1e-07 30.1 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain AAA PF00004.24 KLO11018.1 - 3.1e-06 27.4 0.0 7.6e-06 26.1 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) NACHT PF05729.7 KLO11018.1 - 4.3e-05 23.2 0.0 0.00011 21.9 0.0 1.6 1 0 0 1 1 1 1 NACHT domain AAA_19 PF13245.1 KLO11018.1 - 0.0012 18.5 0.2 0.0067 16.1 0.0 2.3 2 0 0 2 2 2 1 Part of AAA domain Arch_ATPase PF01637.13 KLO11018.1 - 0.0014 18.4 0.0 0.0026 17.4 0.0 1.4 1 0 0 1 1 1 1 Archaeal ATPase DUF2075 PF09848.4 KLO11018.1 - 0.0023 16.9 0.0 0.0031 16.5 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) cobW PF02492.14 KLO11018.1 - 0.0069 15.8 0.0 0.013 14.9 0.0 1.4 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain NB-ARC PF00931.17 KLO11018.1 - 0.014 14.2 0.0 0.025 13.4 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain T2SE PF00437.15 KLO11018.1 - 0.014 14.2 0.0 0.025 13.4 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_11 PF13086.1 KLO11018.1 - 0.027 14.0 0.0 0.049 13.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.1 KLO11018.1 - 0.028 14.3 0.0 0.066 13.1 0.0 1.6 1 1 0 1 1 1 0 AAA domain Helicase_RecD PF05127.9 KLO11018.1 - 0.029 13.9 0.0 0.055 13.0 0.0 1.4 1 0 0 1 1 1 0 Helicase RNA_helicase PF00910.17 KLO11018.1 - 0.065 13.4 0.0 0.15 12.2 0.0 1.7 1 1 0 1 1 1 0 RNA helicase Cdc6_C PF09079.6 KLO11018.1 - 0.13 12.0 0.0 0.29 10.8 0.0 1.5 1 0 0 1 1 1 0 CDC6, C terminal NTPase_1 PF03266.10 KLO11018.1 - 0.13 11.9 0.1 0.28 10.8 0.1 1.5 1 0 0 1 1 1 0 NTPase Abhydrolase_3 PF07859.8 KLO11019.1 - 1.2e-22 80.5 0.0 6.5e-22 78.1 0.0 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold DUF2424 PF10340.4 KLO11019.1 - 2.2e-14 52.9 0.0 4.9e-14 51.7 0.0 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF2424) Abhydrolase_6 PF12697.2 KLO11019.1 - 0.012 15.5 0.1 0.016 15.1 0.1 1.4 1 1 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KLO11019.1 - 0.016 14.9 0.0 0.024 14.4 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family Thioesterase PF00975.15 KLO11019.1 - 0.11 12.7 0.0 0.2 11.8 0.0 1.4 1 0 0 1 1 1 0 Thioesterase domain Haemadin PF09065.5 KLO11020.1 - 0.14 11.7 1.1 0.45 10.1 0.7 1.8 1 0 0 1 1 1 0 Haemadin Pkinase_Tyr PF07714.12 KLO11021.1 - 2.9e-33 115.0 0.0 4.4e-33 114.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 KLO11021.1 - 1.5e-32 112.8 0.0 2.8e-32 111.9 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain DUF4064 PF13273.1 KLO11023.1 - 0.56 10.3 11.7 1.5 8.9 2.5 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF4064) DUF3796 PF12676.2 KLO11025.1 - 0.053 13.7 3.3 0.11 12.7 2.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3796) 7TMR-DISM_7TM PF07695.6 KLO11028.1 - 0.36 10.4 8.3 0.46 10.1 5.8 1.2 1 0 0 1 1 1 0 7TM diverse intracellular signalling ZZ PF00569.12 KLO11030.1 - 4.9e-06 25.9 64.8 0.00063 19.2 4.9 6.6 7 0 0 7 7 7 5 Zinc finger, ZZ type Pkinase PF00069.20 KLO11031.1 - 1.9e-23 82.9 0.0 2.4e-23 82.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KLO11031.1 - 3.1e-19 69.0 0.0 4e-19 68.6 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 KLO11031.1 - 0.028 13.4 0.0 0.076 12.0 0.0 1.6 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 KLO11031.1 - 0.037 13.3 0.0 0.61 9.4 0.0 2.0 2 0 0 2 2 2 0 RIO1 family APH PF01636.18 KLO11031.1 - 0.055 13.2 0.0 0.065 12.9 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family PB1 PF00564.19 KLO11032.1 - 2e-10 40.1 0.0 5.8e-10 38.6 0.0 1.8 1 0 0 1 1 1 1 PB1 domain ZZ PF00569.12 KLO11032.1 - 3.1e-10 39.4 62.0 0.00032 20.1 4.1 6.4 6 0 0 6 6 6 3 Zinc finger, ZZ type TIP_N PF12457.3 KLO11033.1 - 1.2e-09 38.2 8.4 1.2e-09 38.2 5.8 1.9 1 1 1 2 2 2 1 Tuftelin interacting protein N terminal GCFC PF07842.7 KLO11034.1 - 6.3e-81 271.7 5.2 9.4e-81 271.1 3.6 1.3 1 0 0 1 1 1 1 GC-rich sequence DNA-binding factor-like protein G-patch PF01585.18 KLO11034.1 - 8.7e-14 51.0 1.9 1.8e-13 50.0 1.3 1.6 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.2 KLO11034.1 - 7.3e-08 32.1 0.3 2.3e-07 30.5 0.1 1.9 1 1 0 1 1 1 1 DExH-box splicing factor binding site DnaJ-X PF14308.1 KLO11035.1 - 9.3e-55 185.0 0.3 9.3e-55 185.0 0.2 2.3 3 0 0 3 3 3 1 X-domain of DnaJ-containing DnaJ PF00226.26 KLO11035.1 - 2.5e-24 84.7 7.0 5.6e-24 83.6 4.2 2.2 2 0 0 2 2 2 1 DnaJ domain Metal_resist PF13801.1 KLO11035.1 - 0.0021 18.0 7.9 0.22 11.5 0.0 3.5 3 0 0 3 3 3 2 Heavy-metal resistance DUF3782 PF12644.2 KLO11035.1 - 0.0065 16.2 0.0 5.9 6.7 0.1 3.2 2 1 0 2 2 2 2 Protein of unknown function (DUF3782) Ndc1_Nup PF09531.5 KLO11035.1 - 0.0072 14.8 2.3 0.4 9.0 0.8 2.2 2 0 0 2 2 2 2 Nucleoporin protein Ndc1-Nup Aminotran_3 PF00202.16 KLO11036.1 - 2.2e-75 253.6 0.0 3e-75 253.1 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III HECT PF00632.20 KLO11037.1 - 3.7e-83 279.2 0.0 5.6e-83 278.7 0.0 1.3 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Nse4-Nse3_bdg PF15412.1 KLO11037.1 - 0.016 15.0 0.4 0.056 13.2 0.3 2.0 1 0 0 1 1 1 0 Binding domain of Nse4/EID3 to Nse3-MAGE Drf_GBD PF06371.8 KLO11037.1 - 0.11 11.8 0.0 2.3 7.5 0.0 2.7 2 0 0 2 2 2 0 Diaphanous GTPase-binding Domain Arm PF00514.18 KLO11037.1 - 0.14 12.0 1.9 1.6 8.7 0.0 3.8 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat F-box-like PF12937.2 KLO11038.1 - 3.2e-09 36.3 0.0 8.3e-09 35.0 0.0 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KLO11038.1 - 1.2e-05 24.7 2.0 4.1e-05 23.1 0.0 2.5 2 0 0 2 2 2 1 F-box domain DIOX_N PF14226.1 KLO11039.1 - 5.6e-16 59.1 0.0 9.6e-16 58.3 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 KLO11039.1 - 3.1e-12 46.6 0.0 5.3e-12 45.8 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily tRNA-synt_2d PF01409.15 KLO11039.1 - 0.0069 15.6 0.0 0.084 12.0 0.0 2.0 2 0 0 2 2 2 1 tRNA synthetases class II core domain (F) DIOX_N PF14226.1 KLO11040.1 - 1.8e-16 60.7 0.0 3.5e-16 59.7 0.0 1.5 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 KLO11040.1 - 2.8e-12 46.7 0.0 1.9e-10 40.8 0.0 2.4 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily FGGY_N PF00370.16 KLO11041.1 - 2.1e-26 92.7 0.1 4.4e-16 58.9 0.0 2.3 2 0 0 2 2 2 2 FGGY family of carbohydrate kinases, N-terminal domain FGGY_C PF02782.11 KLO11041.1 - 6.6e-22 78.1 0.0 1.7e-21 76.7 0.0 1.7 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain BcrAD_BadFG PF01869.15 KLO11041.1 - 0.02 14.1 0.0 0.8 8.9 0.0 2.2 2 0 0 2 2 2 0 BadF/BadG/BcrA/BcrD ATPase family BTB PF00651.26 KLO11042.1 - 0.00022 21.1 0.0 0.96 9.4 0.0 2.4 2 0 0 2 2 2 2 BTB/POZ domain zf-H2C2_2 PF13465.1 KLO11042.1 - 0.004 17.3 1.1 0.0094 16.2 0.8 1.7 1 0 0 1 1 1 1 Zinc-finger double domain BTB PF00651.26 KLO11043.1 - 0.013 15.4 0.0 8.7 6.3 0.0 2.6 3 0 0 3 3 3 0 BTB/POZ domain HORMA PF02301.13 KLO11044.1 - 2e-15 56.8 0.0 2.4e-15 56.6 0.0 1.1 1 0 0 1 1 1 1 HORMA domain ACC_central PF08326.7 KLO11045.1 - 4.3e-206 686.2 0.0 5.8e-206 685.8 0.0 1.2 1 0 0 1 1 1 1 Acetyl-CoA carboxylase, central region Carboxyl_trans PF01039.17 KLO11045.1 - 7e-163 542.5 0.0 9.3e-163 542.1 0.0 1.2 1 0 0 1 1 1 1 Carboxyl transferase domain CPSase_L_D2 PF02786.12 KLO11045.1 - 4.6e-49 166.5 0.1 8.2e-49 165.7 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_chain PF00289.17 KLO11045.1 - 3.7e-26 91.3 0.1 8.1e-26 90.2 0.0 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, N-terminal domain Biotin_carb_C PF02785.14 KLO11045.1 - 4e-21 74.9 0.0 2.9e-19 69.0 0.0 3.2 3 0 0 3 3 3 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.17 KLO11045.1 - 3.8e-12 45.6 0.2 1.1e-11 44.1 0.0 1.9 2 0 0 2 2 2 1 Biotin-requiring enzyme ATP-grasp_4 PF13535.1 KLO11045.1 - 2.4e-10 40.4 0.0 6.9e-10 38.9 0.0 1.7 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_3 PF02655.9 KLO11045.1 - 0.00095 19.0 0.5 0.01 15.6 0.0 2.7 3 0 0 3 3 3 1 ATP-grasp domain Dala_Dala_lig_C PF07478.8 KLO11045.1 - 0.0039 16.5 0.0 0.0079 15.5 0.0 1.5 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus AAA PF00004.24 KLO11046.1 - 3.2e-42 143.8 0.0 6.5e-42 142.8 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 KLO11046.1 - 1.7e-08 34.6 0.1 1.4e-06 28.4 0.0 3.5 2 1 0 2 2 2 1 AAA ATPase domain AAA_5 PF07728.9 KLO11046.1 - 3.7e-07 29.9 0.2 4.9e-06 26.3 0.1 2.7 3 1 0 3 3 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 KLO11046.1 - 8.2e-06 25.8 0.0 3.1e-05 23.9 0.0 2.0 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.1 KLO11046.1 - 9.2e-06 25.8 0.0 0.00082 19.5 0.0 2.5 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.7 KLO11046.1 - 1.6e-05 24.0 0.0 3.2e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_19 PF13245.1 KLO11046.1 - 4.3e-05 23.1 0.8 0.00022 20.9 0.5 2.1 1 1 1 2 2 2 1 Part of AAA domain AAA_17 PF13207.1 KLO11046.1 - 0.00085 20.1 0.1 0.0025 18.6 0.1 2.1 1 1 0 1 1 1 1 AAA domain DUF815 PF05673.8 KLO11046.1 - 0.00099 18.0 0.0 0.002 17.0 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_33 PF13671.1 KLO11046.1 - 0.0013 18.6 0.0 0.0069 16.2 0.0 2.1 2 0 0 2 2 2 1 AAA domain Mg_chelatase PF01078.16 KLO11046.1 - 0.0027 16.8 0.0 0.0051 15.9 0.0 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.12 KLO11046.1 - 0.0029 17.0 0.0 0.0057 16.0 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein RNA_helicase PF00910.17 KLO11046.1 - 0.0046 17.1 0.0 0.0096 16.0 0.0 1.6 1 0 0 1 1 1 1 RNA helicase TIP49 PF06068.8 KLO11046.1 - 0.0048 15.6 0.0 0.0081 14.9 0.0 1.3 1 0 0 1 1 1 1 TIP49 C-terminus AAA_14 PF13173.1 KLO11046.1 - 0.0056 16.5 0.0 0.011 15.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.1 KLO11046.1 - 0.0073 16.2 0.1 0.019 14.9 0.0 1.8 2 0 0 2 2 1 1 AAA domain AAA_18 PF13238.1 KLO11046.1 - 0.0078 16.5 0.0 0.03 14.6 0.0 2.1 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.7 KLO11046.1 - 0.0081 15.2 0.1 0.02 13.9 0.0 1.6 1 0 0 1 1 1 1 Zeta toxin AAA_25 PF13481.1 KLO11046.1 - 0.0086 15.4 0.2 0.036 13.4 0.1 2.1 1 1 1 2 2 2 1 AAA domain AAA_3 PF07726.6 KLO11046.1 - 0.012 15.2 0.0 0.027 14.0 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.1 KLO11046.1 - 0.012 15.2 0.1 0.027 14.0 0.1 1.5 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.21 KLO11046.1 - 0.013 14.9 0.0 0.059 12.8 0.0 2.1 1 1 0 1 1 1 0 Sigma-54 interaction domain PhoH PF02562.11 KLO11046.1 - 0.014 14.6 0.0 0.025 13.7 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein ResIII PF04851.10 KLO11046.1 - 0.018 14.8 0.1 0.065 13.0 0.0 1.9 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit AAA_30 PF13604.1 KLO11046.1 - 0.026 14.0 0.0 0.074 12.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain KaiC PF06745.8 KLO11046.1 - 0.034 13.2 1.7 0.16 11.0 0.0 2.4 3 0 0 3 3 3 0 KaiC Parvo_NS1 PF01057.12 KLO11046.1 - 0.045 12.6 0.0 0.12 11.2 0.0 1.6 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 NACHT PF05729.7 KLO11046.1 - 0.055 13.1 0.0 0.16 11.6 0.0 1.8 1 1 1 2 2 2 0 NACHT domain Arch_ATPase PF01637.13 KLO11046.1 - 0.088 12.4 0.1 0.46 10.1 0.0 2.3 2 1 0 2 2 2 0 Archaeal ATPase UPF0079 PF02367.12 KLO11046.1 - 0.091 12.3 0.0 0.16 11.5 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 Sigma54_activ_2 PF14532.1 KLO11046.1 - 0.11 12.5 0.0 0.29 11.1 0.0 1.8 1 1 0 1 1 1 0 Sigma-54 interaction domain TPR_MLP1_2 PF07926.7 KLO11046.1 - 0.29 10.8 2.8 0.16 11.7 0.2 1.7 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein WSC PF01822.14 KLO11047.1 - 2.2e-33 114.0 35.8 2.2e-18 65.9 8.3 3.5 3 0 0 3 3 3 2 WSC domain Glyoxal_oxid_N PF07250.6 KLO11047.1 - 2.8e-27 95.3 0.0 5e-25 87.9 0.0 2.9 2 1 1 3 3 3 1 Glyoxal oxidase N-terminus DUF1929 PF09118.6 KLO11047.1 - 2.8e-22 78.6 0.0 5.8e-22 77.6 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1929) Kelch_4 PF13418.1 KLO11047.1 - 0.00035 20.2 0.3 0.58 9.9 0.0 3.8 3 0 0 3 3 3 2 Galactose oxidase, central domain Mitoc_L55 PF09776.4 KLO11047.1 - 0.15 11.6 0.0 2.8 7.5 0.0 2.3 2 0 0 2 2 2 0 Mitochondrial ribosomal protein L55 Kelch_2 PF07646.10 KLO11047.1 - 0.94 9.3 0.0 0.94 9.3 0.0 3.8 6 0 0 6 6 6 0 Kelch motif WSC PF01822.14 KLO11048.1 - 9.7e-37 124.7 35.8 1.7e-20 72.6 10.8 3.5 3 1 0 3 3 3 2 WSC domain DUF605 PF04652.11 KLO11048.1 - 0.16 11.3 6.6 0.2 10.9 4.6 1.1 1 0 0 1 1 1 0 Vta1 like DNA_pol_viral_N PF00242.12 KLO11048.1 - 9.9 5.0 18.0 16 4.3 12.5 1.3 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain GFO_IDH_MocA PF01408.17 KLO11049.1 - 3.3e-25 88.9 0.0 7.6e-25 87.7 0.0 1.6 2 0 0 2 2 2 1 Oxidoreductase family, NAD-binding Rossmann fold Semialdhyde_dh PF01118.19 KLO11049.1 - 0.061 13.6 0.0 0.15 12.3 0.0 1.6 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Granulin PF00396.13 KLO11052.1 - 0.33 11.0 9.4 0.5 10.5 6.5 1.2 1 0 0 1 1 1 0 Granulin RCC1 PF00415.13 KLO11054.1 - 1.7e-18 66.5 5.9 5.7e-05 23.2 0.0 6.5 8 0 0 8 8 8 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 KLO11054.1 - 4.4e-13 48.4 20.9 6.5e-07 28.8 0.6 5.2 6 0 0 6 6 6 3 Regulator of chromosome condensation (RCC1) repeat F-box-like PF12937.2 KLO11054.1 - 4.8e-06 26.1 0.1 1e-05 25.1 0.1 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KLO11054.1 - 0.014 15.0 0.2 0.014 15.0 0.1 2.1 2 0 0 2 2 2 0 F-box domain Dispanin PF04505.7 KLO11057.1 - 3 7.4 5.6 8 6.0 0.1 3.0 3 1 0 3 3 3 0 Interferon-induced transmembrane protein zf-C3HC4 PF00097.20 KLO11058.1 - 1.8e-05 24.2 14.1 4.1e-05 23.1 9.8 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KLO11058.1 - 0.00098 18.9 15.4 0.002 17.9 10.7 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 KLO11058.1 - 0.0064 16.1 11.1 0.017 14.7 7.7 1.7 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KLO11058.1 - 0.028 14.1 13.6 0.074 12.7 9.4 1.8 1 0 0 1 1 1 0 zinc-RING finger domain zf-C3HC4_2 PF13923.1 KLO11058.1 - 0.13 12.3 16.2 0.31 11.0 11.2 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) OmpH PF03938.9 KLO11058.1 - 0.13 12.1 3.2 0.23 11.4 2.2 1.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF3552 PF12072.3 KLO11058.1 - 0.15 11.2 7.2 0.25 10.5 5.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) zf-C3HC4_4 PF15227.1 KLO11058.1 - 0.16 11.8 14.5 0.85 9.5 10.1 2.3 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.2 KLO11058.1 - 0.21 11.6 9.2 0.59 10.2 6.4 1.8 1 1 0 1 1 1 0 RING-H2 zinc finger Tmpp129 PF10272.4 KLO11058.1 - 0.22 10.1 3.5 0.37 9.4 2.4 1.2 1 0 0 1 1 1 0 Putative transmembrane protein precursor zf-RING_6 PF14835.1 KLO11058.1 - 8.5 6.2 11.4 29 4.5 7.9 1.9 1 1 0 1 1 1 0 zf-RING of BARD1-type protein PHB_acc PF05233.8 KLO11060.1 - 0.11 12.2 1.3 0.59 9.9 0.4 2.0 2 0 0 2 2 2 0 PHB accumulation regulatory domain DUF4209 PF13910.1 KLO11060.1 - 0.12 12.4 0.1 0.12 12.4 0.1 1.2 1 1 0 1 1 1 0 Domain of unknown function (DUF4209) zf-C2H2 PF00096.21 KLO11064.1 - 0.017 15.3 0.4 0.033 14.5 0.3 1.5 1 0 0 1 1 1 0 Zinc finger, C2H2 type DUF1644 PF07800.7 KLO11064.1 - 0.054 13.3 0.5 0.061 13.1 0.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1644) Myb_DNA-bind_5 PF13873.1 KLO11064.1 - 0.065 13.1 0.9 0.086 12.7 0.2 1.6 2 0 0 2 2 2 0 Myb/SANT-like DNA-binding domain RCC1 PF00415.13 KLO11069.1 - 5.1e-17 61.8 6.7 0.00048 20.2 0.1 7.3 8 0 0 8 8 8 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 KLO11069.1 - 2.5e-15 55.5 17.5 4e-07 29.4 0.2 4.7 4 0 0 4 4 4 3 Regulator of chromosome condensation (RCC1) repeat F-box-like PF12937.2 KLO11069.1 - 0.00065 19.3 0.0 0.0012 18.4 0.0 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KLO11069.1 - 0.007 16.0 0.1 0.015 14.9 0.1 1.6 1 0 0 1 1 1 1 F-box domain Elongin_A PF06881.6 KLO11069.1 - 0.11 12.9 0.0 0.28 11.5 0.0 1.7 1 0 0 1 1 1 0 RNA polymerase II transcription factor SIII (Elongin) subunit A WD40 PF00400.27 KLO11071.1 - 1.2e-41 139.1 33.9 4.6e-07 29.4 0.0 13.4 14 0 0 14 14 14 10 WD domain, G-beta repeat NACHT PF05729.7 KLO11071.1 - 1.5e-08 34.5 0.0 3.2e-08 33.3 0.0 1.5 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 KLO11071.1 - 1e-06 28.8 0.0 4.6e-06 26.7 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain Apc4_WD40 PF12894.2 KLO11071.1 - 4.8e-06 25.9 0.0 0.00065 19.1 0.0 3.3 3 0 0 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.3 KLO11071.1 - 1.9e-05 23.0 0.6 0.0024 16.1 0.0 3.7 4 1 0 4 4 4 1 Nucleoporin Nup120/160 Nbas_N PF15492.1 KLO11071.1 - 7.9e-05 21.8 1.2 0.058 12.4 0.1 5.2 6 1 0 6 6 6 1 Neuroblastoma-amplified sequence, N terminal AAA PF00004.24 KLO11071.1 - 8.5e-05 22.7 0.0 0.00027 21.1 0.0 1.9 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) NB-ARC PF00931.17 KLO11071.1 - 0.0005 19.0 0.0 0.00093 18.1 0.0 1.4 1 0 0 1 1 1 1 NB-ARC domain AAA_22 PF13401.1 KLO11071.1 - 0.0039 17.3 0.0 0.0093 16.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 KLO11071.1 - 0.004 16.2 0.0 0.0078 15.3 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin KAP_NTPase PF07693.9 KLO11071.1 - 0.0082 15.1 0.4 1.1 8.2 0.0 2.2 2 0 0 2 2 2 1 KAP family P-loop domain AAA_17 PF13207.1 KLO11071.1 - 0.011 16.5 0.3 0.09 13.5 0.0 2.8 3 0 0 3 3 1 0 AAA domain RNA_helicase PF00910.17 KLO11071.1 - 0.015 15.5 0.0 0.058 13.5 0.0 2.0 2 0 0 2 2 1 0 RNA helicase Hira PF07569.6 KLO11071.1 - 0.015 14.4 0.1 0.47 9.6 0.0 3.2 4 0 0 4 4 4 0 TUP1-like enhancer of split Viral_helicase1 PF01443.13 KLO11071.1 - 0.039 13.4 0.0 0.065 12.7 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase PD40 PF07676.7 KLO11071.1 - 0.058 13.0 4.4 56 3.5 0.0 6.1 8 0 0 8 8 7 0 WD40-like Beta Propeller Repeat APS_kinase PF01583.15 KLO11071.1 - 0.09 12.4 0.0 0.18 11.4 0.0 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA_18 PF13238.1 KLO11071.1 - 0.091 13.0 0.0 0.42 10.9 0.0 2.2 2 0 0 2 2 2 0 AAA domain Gmad1 PF10647.4 KLO11071.1 - 0.11 11.8 0.0 4.3 6.6 0.0 2.6 2 1 0 2 2 2 0 Lipoprotein LpqB beta-propeller domain DUF2075 PF09848.4 KLO11071.1 - 0.14 11.0 0.0 0.25 10.2 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) FtsK_SpoIIIE PF01580.13 KLO11071.1 - 0.18 11.2 0.0 0.95 8.9 0.0 2.1 2 0 0 2 2 2 0 FtsK/SpoIIIE family PH PF00169.24 KLO11072.1 - 1e-08 35.3 0.0 3.7e-08 33.5 0.0 2.0 2 0 0 2 2 2 1 PH domain APH PF01636.18 KLO11073.1 - 4e-15 56.1 0.0 6.4e-15 55.5 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 KLO11073.1 - 0.00015 21.3 0.0 0.00023 20.8 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase EcKinase PF02958.15 KLO11073.1 - 0.0053 15.9 0.0 0.0078 15.3 0.0 1.3 1 0 0 1 1 1 1 Ecdysteroid kinase Kri1_C PF12936.2 KLO11074.1 - 2e-21 75.7 0.0 2e-21 75.7 0.0 4.5 3 1 0 3 3 3 1 KRI1-like family C-terminal Kri1 PF05178.7 KLO11074.1 - 2.2e-21 76.0 12.4 2.2e-21 76.0 8.6 6.7 7 0 0 7 7 7 2 KRI1-like family RepB-RCR_reg PF10723.4 KLO11074.1 - 5.6 6.7 11.4 0.24 11.1 3.1 2.4 2 0 0 2 2 2 0 Replication regulatory protein RepB Peptidase_S8 PF00082.17 KLO11075.1 - 3.3e-51 174.0 7.1 4.5e-51 173.6 4.9 1.1 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.11 KLO11075.1 - 2e-10 41.1 0.0 3.6e-10 40.2 0.0 1.5 1 0 0 1 1 1 1 Peptidase inhibitor I9 Response_reg PF00072.19 KLO11076.1 - 1.2e-23 83.2 0.1 1.7e-17 63.4 0.0 2.0 1 1 1 2 2 2 2 Response regulator receiver domain DUF3678 PF12435.3 KLO11076.1 - 0.085 12.4 0.5 0.13 11.7 0.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3678) ER_lumen_recept PF00810.13 KLO11079.1 - 2.5e-57 193.5 7.9 3.4e-57 193.0 5.5 1.2 1 0 0 1 1 1 1 ER lumen protein retaining receptor PQ-loop PF04193.9 KLO11079.1 - 0.0012 18.3 5.9 1.8 8.1 0.0 4.0 3 1 1 4 4 4 3 PQ loop repeat Transp_cyt_pur PF02133.10 KLO11080.1 - 1.8e-161 537.5 40.8 2.1e-161 537.3 28.3 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin HEAT_EZ PF13513.1 KLO11081.1 - 4.2e-23 81.1 15.0 8.9e-12 45.1 0.0 9.9 7 3 4 11 11 11 4 HEAT-like repeat HEAT_2 PF13646.1 KLO11081.1 - 2e-21 76.0 0.1 1.1e-05 25.6 0.0 7.4 4 3 6 10 10 10 6 HEAT repeats HEAT PF02985.17 KLO11081.1 - 3.4e-20 70.2 17.0 2.1e-05 24.2 0.0 10.5 11 0 0 11 11 11 5 HEAT repeat Vac14_Fab1_bd PF12755.2 KLO11081.1 - 1.2e-09 38.4 0.0 0.0044 17.3 0.0 4.4 4 1 1 5 5 5 2 Vacuolar 14 Fab1-binding region Cnd1 PF12717.2 KLO11081.1 - 2.6e-06 27.4 0.6 2.4 7.9 0.2 6.0 5 3 1 6 6 6 1 non-SMC mitotic condensation complex subunit 1 Arm PF00514.18 KLO11081.1 - 0.00018 21.2 1.4 0.41 10.5 0.0 5.4 6 0 0 6 6 6 1 Armadillo/beta-catenin-like repeat Adaptin_N PF01602.15 KLO11081.1 - 0.0025 16.2 0.4 0.09 11.0 0.0 2.9 3 0 0 3 3 3 1 Adaptin N terminal region Cohesin_HEAT PF12765.2 KLO11081.1 - 0.0077 16.1 1.9 32 4.6 0.1 5.0 6 0 0 6 6 6 0 HEAT repeat associated with sister chromatid cohesion DUF2454 PF10521.4 KLO11081.1 - 0.059 12.3 0.2 11 4.9 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2454) DUF2435 PF10363.4 KLO11081.1 - 0.068 13.0 0.2 0.77 9.6 0.0 2.8 3 0 0 3 3 2 0 Protein of unknown function (DUF2435) RIX1 PF08167.7 KLO11081.1 - 0.11 12.1 0.1 23 4.6 0.0 4.0 5 0 0 5 5 5 0 rRNA processing/ribosome biogenesis HTH_Tnp_1 PF01527.15 KLO11081.1 - 0.14 12.1 0.0 0.33 10.9 0.0 1.5 1 0 0 1 1 1 0 Transposase FSH1 PF03959.8 KLO11082.1 - 1.2e-54 184.9 0.0 1.4e-54 184.7 0.0 1.0 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_5 PF12695.2 KLO11082.1 - 1.2e-06 28.3 0.0 2.1e-06 27.5 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KLO11082.1 - 0.00057 19.8 3.1 0.013 15.4 2.1 2.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 KLO11082.1 - 0.013 14.9 0.3 1.8 7.9 0.0 2.5 3 0 0 3 3 3 0 Phospholipase/Carboxylesterase Mito_carr PF00153.22 KLO11083.1 - 5.2e-67 221.6 2.4 6.2e-22 77.1 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Fungal_trans PF04082.13 KLO11085.1 - 1.5e-19 69.8 0.0 2.9e-19 68.9 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KLO11085.1 - 6.5e-05 22.7 14.9 0.00011 21.9 10.3 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain AKNA PF12443.3 KLO11085.1 - 0.082 12.9 0.1 0.26 11.3 0.1 1.9 1 0 0 1 1 1 0 AT-hook-containing transcription factor MGDG_synth PF06925.6 KLO11086.1 - 0.11 12.4 0.0 0.18 11.6 0.0 1.4 1 0 0 1 1 1 0 Monogalactosyldiacylglycerol (MGDG) synthase DUF3328 PF11807.3 KLO11088.1 - 3.4e-15 56.3 0.6 6.1e-15 55.4 0.4 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF3328) PrgH PF09480.5 KLO11088.1 - 0.13 11.1 0.0 0.16 10.8 0.0 1.1 1 0 0 1 1 1 0 Type III secretion system protein PrgH-EprH (PrgH) DUF3328 PF11807.3 KLO11090.1 - 1.9e-12 47.3 0.0 2.5e-12 46.9 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) Acetyltransf_1 PF00583.19 KLO11091.1 - 1.8e-07 31.0 0.0 3.2e-07 30.2 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 KLO11091.1 - 4.2e-05 23.6 0.0 0.00026 21.0 0.0 2.2 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 KLO11091.1 - 0.0023 18.0 0.1 0.0074 16.3 0.0 2.0 1 1 1 2 2 2 1 Acetyltransferase (GNAT) domain DUF3749 PF12568.3 KLO11091.1 - 0.0083 15.7 0.1 0.02 14.4 0.0 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 KLO11091.1 - 0.027 14.3 0.0 3.1 7.6 0.0 2.3 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain FR47 PF08445.5 KLO11091.1 - 0.042 13.6 0.0 0.098 12.4 0.0 1.6 1 0 0 1 1 1 0 FR47-like protein Acetyltransf_1 PF00583.19 KLO11092.1 - 2.6e-10 40.2 0.1 4.2e-10 39.5 0.1 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 KLO11092.1 - 1.9e-05 24.7 0.0 6.1e-05 23.1 0.0 2.0 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 KLO11092.1 - 9.4e-05 22.2 0.1 0.001 18.9 0.0 2.5 2 1 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 KLO11092.1 - 0.00011 22.3 0.3 0.00047 20.2 0.1 2.1 1 1 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 KLO11092.1 - 0.0051 16.6 0.0 0.0088 15.9 0.0 1.4 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase FR47 PF08445.5 KLO11092.1 - 0.033 13.9 0.0 0.08 12.7 0.0 1.6 1 0 0 1 1 1 0 FR47-like protein SNF2_N PF00176.18 KLO11093.1 - 1.5e-70 237.3 0.6 1.5e-70 237.3 0.4 1.7 2 0 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.26 KLO11093.1 - 2.7e-13 49.5 0.1 2e-12 46.8 0.1 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain HDA2-3 PF11496.3 KLO11093.1 - 0.014 14.2 0.3 5.7 5.6 0.0 2.7 2 1 0 2 2 2 0 Class II histone deacetylase complex subunits 2 and 3 Pkinase PF00069.20 KLO11095.1 - 1.7e-66 224.0 0.0 2e-66 223.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KLO11095.1 - 5e-37 127.3 0.0 6.5e-37 126.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KLO11095.1 - 0.046 12.6 0.0 0.11 11.4 0.0 1.7 2 0 0 2 2 2 0 Kinase-like Kdo PF06293.9 KLO11095.1 - 0.05 12.6 0.0 0.1 11.6 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DnaJ PF00226.26 KLO11096.1 - 4.5e-13 48.7 0.0 7.3e-13 48.0 0.0 1.3 1 0 0 1 1 1 1 DnaJ domain Totivirus_coat PF05518.6 KLO11096.1 - 5.2 4.7 5.7 7.4 4.2 3.9 1.1 1 0 0 1 1 1 0 Totivirus coat protein Yippee-Mis18 PF03226.9 KLO11097.1 - 4.6e-09 36.2 0.1 6e-09 35.8 0.1 1.2 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly DUF3627 PF12299.3 KLO11098.1 - 0.11 12.5 0.1 0.17 11.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3627) Syja_N PF02383.13 KLO11099.1 - 8.5e-85 284.3 0.0 1.3e-84 283.6 0.0 1.3 1 0 0 1 1 1 1 SacI homology domain Glyco_hydro_43 PF04616.9 KLO11100.1 - 3.3e-69 233.1 0.5 4.2e-69 232.8 0.3 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 F5_F8_type_C PF00754.20 KLO11100.1 - 0.019 14.7 1.5 1 9.1 0.1 3.2 3 0 0 3 3 3 0 F5/8 type C domain XPG_N PF00752.12 KLO11101.1 - 8.1e-34 115.9 0.0 1.7e-33 114.8 0.0 1.6 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.13 KLO11101.1 - 1.1e-28 99.0 0.0 2.2e-28 98.1 0.0 1.5 1 0 0 1 1 1 1 XPG I-region 5_3_exonuc PF01367.15 KLO11101.1 - 6.9e-07 29.4 0.1 1.9e-06 28.0 0.0 1.8 1 0 0 1 1 1 1 5'-3' exonuclease, C-terminal SAM fold Fe_dep_repr_C PF02742.10 KLO11101.1 - 0.0081 15.8 0.0 0.032 13.9 0.0 2.0 1 0 0 1 1 1 1 Iron dependent repressor, metal binding and dimerisation domain HHH_5 PF14520.1 KLO11101.1 - 0.058 13.5 0.5 0.19 11.9 0.0 2.2 3 0 0 3 3 3 0 Helix-hairpin-helix domain NUFIP2 PF15293.1 KLO11101.1 - 0.49 9.0 9.6 6.6 5.3 0.0 2.2 2 0 0 2 2 2 0 Nuclear fragile X mental retardation-interacting protein 2 Ank_4 PF13637.1 KLO11102.1 - 6.7e-07 29.6 0.3 0.0014 19.1 0.0 3.6 2 1 2 4 4 4 2 Ankyrin repeats (many copies) Ank_5 PF13857.1 KLO11102.1 - 0.00033 20.8 0.8 12 6.3 0.0 4.5 3 1 2 5 5 5 2 Ankyrin repeats (many copies) Ank_2 PF12796.2 KLO11102.1 - 0.00034 20.9 0.0 0.0087 16.3 0.0 2.5 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.1 KLO11102.1 - 0.0023 17.9 0.1 28 5.3 0.0 4.8 5 0 0 5 5 5 1 Ankyrin repeat DUF2263 PF10021.4 KLO11103.1 - 1.3e-18 67.4 0.0 1.8e-18 66.9 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2263) 2-Hacid_dh_C PF02826.14 KLO11104.1 - 2.2e-50 170.2 0.0 2.9e-50 169.8 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 KLO11104.1 - 3e-18 65.5 0.0 3.9e-18 65.1 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 KLO11104.1 - 0.039 13.8 0.0 0.066 13.0 0.0 1.3 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase DCA16 PF15349.1 KLO11104.1 - 0.15 11.4 0.0 0.23 10.7 0.0 1.2 1 0 0 1 1 1 0 DDB1- and CUL4-associated factor 16 SWIB PF02201.13 KLO11105.1 - 1.2e-24 85.7 0.1 2e-24 85.0 0.1 1.4 1 0 0 1 1 1 1 SWIB/MDM2 domain DEK_C PF08766.6 KLO11105.1 - 1.1e-06 28.3 0.3 2.1e-06 27.3 0.2 1.5 1 0 0 1 1 1 1 DEK C terminal domain DUF1194 PF06707.6 KLO11105.1 - 0.08 11.9 0.8 0.13 11.2 0.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1194) PPTA PF01239.17 KLO11106.1 - 2.7e-10 39.1 18.2 2.8e-07 29.5 0.5 5.0 5 1 0 5 5 5 4 Protein prenyltransferase alpha subunit repeat DUF1183 PF06682.7 KLO11107.1 - 0.016 14.8 0.0 0.017 14.7 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1183) Sel1 PF08238.7 KLO11108.1 - 4.3e-31 106.6 24.5 7.8e-06 26.3 0.1 11.2 11 1 0 11 11 11 7 Sel1 repeat RNase_T PF00929.19 KLO11108.1 - 2.5e-13 50.6 0.0 4.5e-13 49.7 0.0 1.5 1 0 0 1 1 1 1 Exonuclease TPR_11 PF13414.1 KLO11108.1 - 8.4e-06 25.3 4.8 0.032 13.8 0.5 4.7 6 0 0 6 6 6 2 TPR repeat TPR_6 PF13174.1 KLO11108.1 - 0.0018 18.5 4.3 20 5.9 0.0 6.9 8 0 0 8 8 8 0 Tetratricopeptide repeat TPR_16 PF13432.1 KLO11108.1 - 0.023 15.3 7.2 0.39 11.4 0.0 5.3 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_12 PF13424.1 KLO11108.1 - 0.032 14.1 3.1 0.71 9.8 0.1 3.9 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.23 KLO11108.1 - 0.059 13.0 7.1 0.37 10.4 0.0 5.1 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_2 PF07719.12 KLO11108.1 - 0.088 12.7 0.0 0.088 12.7 0.0 6.4 8 0 0 8 8 8 0 Tetratricopeptide repeat Herpes_TAF50 PF03326.8 KLO11111.1 - 0.026 13.4 1.3 0.029 13.3 0.9 1.0 1 0 0 1 1 1 0 Herpesvirus transcription activation factor (transactivator) AKAP7_NLS PF10469.4 KLO11112.1 - 2.6e-12 46.9 0.0 9.3e-11 41.8 0.0 2.0 1 1 0 1 1 1 1 AKAP7 2'5' RNA ligase-like domain CAF-1_p150 PF11600.3 KLO11113.1 - 0.21 10.9 2.6 0.26 10.6 1.8 1.2 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal G-alpha PF00503.15 KLO11114.1 - 9.9e-91 304.3 0.0 1.7e-90 303.5 0.0 1.3 1 1 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 KLO11114.1 - 2.7e-07 30.0 0.0 0.00054 19.2 0.0 2.4 2 0 0 2 2 2 2 ADP-ribosylation factor family AAA_29 PF13555.1 KLO11114.1 - 0.024 14.1 0.1 0.066 12.7 0.0 1.7 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_22 PF13401.1 KLO11114.1 - 0.04 14.0 0.0 0.084 13.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain DUF605 PF04652.11 KLO11114.1 - 0.45 9.8 16.0 0.76 9.1 11.1 1.3 1 0 0 1 1 1 0 Vta1 like BTB PF00651.26 KLO11115.1 - 7.5e-07 29.1 0.0 1.5e-06 28.1 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain Skp1_POZ PF03931.10 KLO11115.1 - 0.048 13.7 0.1 0.15 12.2 0.1 1.9 1 0 0 1 1 1 0 Skp1 family, tetramerisation domain BTB PF00651.26 KLO11117.1 - 9.9e-07 28.7 0.0 1.9e-06 27.8 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain BTB PF00651.26 KLO11118.1 - 2e-08 34.1 0.0 3.4e-08 33.4 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain Skp1_POZ PF03931.10 KLO11118.1 - 0.035 14.2 0.1 0.057 13.5 0.1 1.3 1 0 0 1 1 1 0 Skp1 family, tetramerisation domain ABC_tran PF00005.22 KLO11119.1 - 1.6e-46 158.0 0.0 1.4e-22 80.4 0.0 2.8 3 0 0 3 3 2 2 ABC transporter ABC_tran_2 PF12848.2 KLO11119.1 - 7e-21 73.8 3.9 7e-21 73.8 2.7 2.1 3 0 0 3 3 1 1 ABC transporter AAA_21 PF13304.1 KLO11119.1 - 9.7e-19 68.4 1.9 0.00081 19.4 0.0 4.5 4 1 1 5 5 4 4 AAA domain AAA_29 PF13555.1 KLO11119.1 - 9.7e-10 37.8 0.4 0.00081 18.8 0.1 2.4 2 0 0 2 2 2 2 P-loop containing region of AAA domain SMC_N PF02463.14 KLO11119.1 - 1.8e-08 33.8 1.5 0.49 9.5 0.1 4.4 4 0 0 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_16 PF13191.1 KLO11119.1 - 7.2e-08 32.6 0.0 0.0096 15.9 0.0 2.5 2 0 0 2 2 2 2 AAA ATPase domain AAA_23 PF13476.1 KLO11119.1 - 2.9e-06 27.7 14.5 0.018 15.3 0.8 4.0 4 1 0 4 4 3 2 AAA domain Miro PF08477.8 KLO11119.1 - 4.8e-06 27.0 0.0 0.085 13.3 0.0 2.8 2 0 0 2 2 2 2 Miro-like protein NACHT PF05729.7 KLO11119.1 - 1.1e-05 25.1 0.0 0.045 13.4 0.0 2.5 2 0 0 2 2 2 2 NACHT domain AAA_25 PF13481.1 KLO11119.1 - 5e-05 22.7 0.0 1.1 8.6 0.0 3.4 3 0 0 3 3 3 2 AAA domain AAA_22 PF13401.1 KLO11119.1 - 6.2e-05 23.1 1.6 0.049 13.7 0.0 3.9 2 2 0 2 2 2 1 AAA domain AAA_18 PF13238.1 KLO11119.1 - 6.3e-05 23.2 1.6 0.11 12.8 0.0 3.6 4 0 0 4 4 4 1 AAA domain AAA_28 PF13521.1 KLO11119.1 - 0.00011 22.1 0.0 0.12 12.3 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 KLO11119.1 - 0.00014 22.6 3.6 0.11 13.3 0.1 3.1 2 2 0 2 2 2 2 AAA domain MMR_HSR1 PF01926.18 KLO11119.1 - 0.00025 20.9 0.3 1.4 8.9 0.2 3.0 2 1 0 2 2 2 2 50S ribosome-binding GTPase FtsK_SpoIIIE PF01580.13 KLO11119.1 - 0.00028 20.4 0.2 0.32 10.4 0.0 2.7 3 0 0 3 3 2 2 FtsK/SpoIIIE family AAA_10 PF12846.2 KLO11119.1 - 0.00037 20.0 0.1 0.31 10.4 0.0 3.0 3 1 0 3 3 3 1 AAA-like domain DUF258 PF03193.11 KLO11119.1 - 0.00041 19.5 0.0 0.34 10.0 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_15 PF13175.1 KLO11119.1 - 0.00047 19.3 14.0 0.27 10.2 0.0 4.7 3 2 2 5 5 4 3 AAA ATPase domain AAA_14 PF13173.1 KLO11119.1 - 0.0012 18.7 0.0 8.2 6.3 0.0 4.0 4 1 0 4 4 4 0 AAA domain Dynamin_N PF00350.18 KLO11119.1 - 0.0024 17.7 1.6 1.9 8.2 0.1 4.0 2 1 1 3 3 3 1 Dynamin family Arch_ATPase PF01637.13 KLO11119.1 - 0.0024 17.5 2.7 0.14 11.8 0.0 3.3 3 1 0 3 3 3 1 Archaeal ATPase MobB PF03205.9 KLO11119.1 - 0.0032 17.1 3.6 2.7 7.7 0.1 3.5 2 1 1 3 3 3 1 Molybdopterin guanine dinucleotide synthesis protein B SbcCD_C PF13558.1 KLO11119.1 - 0.0042 16.9 0.0 0.89 9.5 0.0 2.9 2 1 0 2 2 2 1 Putative exonuclease SbcCD, C subunit RNA_helicase PF00910.17 KLO11119.1 - 0.0057 16.8 2.7 3.9 7.6 0.0 3.3 3 0 0 3 3 3 0 RNA helicase DUF87 PF01935.12 KLO11119.1 - 0.0061 16.3 4.9 1 9.1 0.1 3.6 4 1 0 4 4 2 2 Domain of unknown function DUF87 AAA_5 PF07728.9 KLO11119.1 - 0.0066 16.1 0.0 2.5 7.8 0.0 3.0 3 0 0 3 3 2 1 AAA domain (dynein-related subfamily) AAA_30 PF13604.1 KLO11119.1 - 0.0067 16.0 0.0 1.2 8.6 0.0 2.9 2 0 0 2 2 2 1 AAA domain NTPase_1 PF03266.10 KLO11119.1 - 0.0081 15.8 1.0 5.7 6.6 0.2 3.3 3 0 0 3 3 3 0 NTPase ATP-synt_ab PF00006.20 KLO11119.1 - 0.0096 15.4 0.0 0.36 10.2 0.0 2.4 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain AAA_19 PF13245.1 KLO11119.1 - 0.0098 15.6 0.0 0.69 9.6 0.0 2.7 2 0 0 2 2 2 1 Part of AAA domain AAA PF00004.24 KLO11119.1 - 0.011 15.8 0.0 7 6.8 0.0 3.4 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) NB-ARC PF00931.17 KLO11119.1 - 0.014 14.2 0.0 0.55 9.0 0.0 2.4 2 0 0 2 2 2 0 NB-ARC domain cobW PF02492.14 KLO11119.1 - 0.014 14.8 0.4 0.54 9.6 0.0 2.7 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain PduV-EutP PF10662.4 KLO11119.1 - 0.016 14.6 0.3 3 7.3 0.0 2.9 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation AAA_33 PF13671.1 KLO11119.1 - 0.017 15.0 0.0 8.5 6.2 0.0 2.9 3 0 0 3 3 2 0 AAA domain DAP3 PF10236.4 KLO11119.1 - 0.017 14.0 2.0 4.1 6.2 0.0 3.3 3 0 0 3 3 3 0 Mitochondrial ribosomal death-associated protein 3 DUF2813 PF11398.3 KLO11119.1 - 0.38 9.7 3.0 5.2 6.0 0.1 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF2813) AAA_13 PF13166.1 KLO11119.1 - 0.42 9.0 7.2 3.1 6.1 0.0 3.3 4 0 0 4 4 4 0 AAA domain MFS_1 PF07690.11 KLO11122.1 - 1.2e-22 80.1 39.7 3.3e-22 78.6 27.1 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Chal_sti_synt_N PF00195.14 KLO11122.1 - 0.017 14.3 0.1 0.028 13.6 0.1 1.3 1 0 0 1 1 1 0 Chalcone and stilbene synthases, N-terminal domain DUF605 PF04652.11 KLO11123.1 - 5.3 6.3 21.1 6.4 6.0 14.6 1.2 1 0 0 1 1 1 0 Vta1 like zf-MYND PF01753.13 KLO11124.1 - 7.6e-12 44.8 10.4 1.4e-11 44.0 7.2 1.5 1 0 0 1 1 1 1 MYND finger zf-MYND PF01753.13 KLO11125.1 - 7e-11 41.8 9.0 1.6e-10 40.7 6.3 1.6 1 0 0 1 1 1 1 MYND finger FYVE_2 PF02318.11 KLO11125.1 - 0.44 10.4 4.7 0.087 12.7 0.6 1.8 2 0 0 2 2 2 0 FYVE-type zinc finger G-alpha PF00503.15 KLO11127.1 - 1.1e-109 366.6 0.0 1.8e-109 366.0 0.0 1.2 1 1 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 KLO11127.1 - 1.1e-07 31.2 0.0 9.6e-07 28.1 0.0 2.2 2 0 0 2 2 2 1 ADP-ribosylation factor family Serglycin PF04360.7 KLO11127.1 - 0.19 11.4 0.7 0.4 10.4 0.5 1.5 1 0 0 1 1 1 0 Serglycin Nepo_coat_N PF03689.10 KLO11128.1 - 0.022 14.4 0.0 0.059 13.0 0.0 1.7 2 0 0 2 2 2 0 Nepovirus coat protein, N-terminal domain zf-MYND PF01753.13 KLO11129.1 - 1.2e-07 31.4 17.2 9.5e-07 28.5 11.9 2.3 1 1 0 1 1 1 1 MYND finger Mei4 PF13971.1 KLO11129.1 - 0.05 12.5 0.0 0.071 12.0 0.0 1.2 1 0 0 1 1 1 0 Meiosis-specific protein Mei4 zf-Mss51 PF13824.1 KLO11129.1 - 0.51 10.2 5.4 1.3 8.9 3.8 1.7 1 0 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 zf-MYND PF01753.13 KLO11130.1 - 2e-11 43.5 8.7 4.4e-11 42.4 6.0 1.6 1 0 0 1 1 1 1 MYND finger Pkinase PF00069.20 KLO11131.1 - 1.1e-36 126.3 0.0 1.2e-36 126.2 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KLO11131.1 - 3.8e-35 121.1 0.0 4.4e-35 120.9 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 KLO11131.1 - 7.3e-05 22.6 0.1 0.00014 21.6 0.0 1.6 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.1 KLO11131.1 - 0.00017 20.6 0.0 0.00023 20.2 0.0 1.1 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 KLO11131.1 - 0.0011 18.1 0.0 0.0014 17.7 0.0 1.1 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH_6_hur PF04655.9 KLO11131.1 - 0.002 17.3 0.0 0.0031 16.7 0.0 1.2 1 0 0 1 1 1 1 Aminoglycoside/hydroxyurea antibiotic resistance kinase RIO1 PF01163.17 KLO11131.1 - 0.16 11.2 0.0 0.24 10.7 0.0 1.3 1 0 0 1 1 1 0 RIO1 family Pkinase_Tyr PF07714.12 KLO11132.1 - 2e-05 23.8 0.1 2.3e-05 23.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 KLO11132.1 - 0.0015 17.7 0.0 0.0018 17.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain DUF1560 PF07597.6 KLO11133.1 - 0.079 12.9 0.7 7.7 6.6 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1560) Sars6 PF12133.3 KLO11136.1 - 0.075 12.7 0.1 0.13 11.9 0.0 1.3 1 0 0 1 1 1 0 Open reading frame 6 from SARS coronavirus Pkinase PF00069.20 KLO11142.1 - 2e-31 109.1 0.0 1.2e-30 106.4 0.0 1.9 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 KLO11142.1 - 1.7e-29 102.7 0.0 4.1e-29 101.4 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.18 KLO11142.1 - 0.09 12.4 0.0 0.15 11.7 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family DUF3384 PF11864.3 KLO11142.1 - 0.17 10.2 0.2 0.24 9.8 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3384) zf-MYND PF01753.13 KLO11145.1 - 8.5e-11 41.5 9.9 1.8e-10 40.5 6.9 1.6 1 0 0 1 1 1 1 MYND finger Nucleoplasmin PF03066.10 KLO11147.1 - 0.00066 19.2 1.4 0.00073 19.0 0.9 1.2 1 0 0 1 1 1 1 Nucleoplasmin PBP1_TM PF14812.1 KLO11147.1 - 0.0012 19.1 3.6 0.0024 18.1 2.5 1.5 1 0 0 1 1 1 1 Transmembrane domain of transglycosylase PBP1 at N-terminal RXT2_N PF08595.6 KLO11147.1 - 0.016 15.0 3.2 0.02 14.6 2.0 1.4 1 1 0 1 1 1 0 RXT2-like, N-terminal zf-CCHC_2 PF13696.1 KLO11147.1 - 0.022 14.2 1.3 0.036 13.5 0.9 1.3 1 0 0 1 1 1 0 Zinc knuckle Nop14 PF04147.7 KLO11147.1 - 0.069 11.0 4.3 0.22 9.4 0.8 2.0 2 0 0 2 2 2 0 Nop14-like family Sigma70_ner PF04546.8 KLO11147.1 - 0.23 11.0 5.1 0.35 10.4 1.7 1.9 2 0 0 2 2 2 0 Sigma-70, non-essential region DUF4611 PF15387.1 KLO11147.1 - 0.48 10.5 12.9 0.92 9.6 5.9 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) eIF3g PF12353.3 KLO11147.1 - 3.7 7.4 8.2 1.4 8.8 3.6 1.9 2 1 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit G CENP-B_dimeris PF09026.5 KLO11147.1 - 6.7 7.0 11.3 7 6.9 6.9 1.6 2 0 0 2 2 2 0 Centromere protein B dimerisation domain MULE PF10551.4 KLO11148.1 - 5.6e-07 29.6 0.4 2.8e-06 27.3 0.0 2.5 2 0 0 2 2 2 1 MULE transposase domain Transposase_mut PF00872.13 KLO11148.1 - 0.036 12.6 0.0 0.068 11.7 0.0 1.4 1 0 0 1 1 1 0 Transposase, Mutator family P53_TAD PF08563.6 KLO11148.1 - 0.091 11.8 0.0 0.17 10.9 0.0 1.4 1 0 0 1 1 1 0 P53 transactivation motif E1-E2_ATPase PF00122.15 KLO11149.1 - 1.4e-74 250.0 0.0 3e-74 248.9 0.0 1.6 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 KLO11149.1 - 7.3e-36 123.3 2.2 7.3e-36 123.3 1.5 1.7 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 KLO11149.1 - 3.3e-28 99.5 0.0 2.3e-27 96.8 0.0 2.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 KLO11149.1 - 1.1e-14 55.1 0.0 2.8e-14 53.7 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 KLO11149.1 - 1.8e-12 47.0 0.0 4.5e-12 45.7 0.0 1.7 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Cation_ATPase_N PF00690.21 KLO11149.1 - 7e-12 44.6 0.0 1.8e-11 43.3 0.0 1.8 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 KLO11149.1 - 0.00045 19.8 1.3 0.00093 18.8 0.5 1.8 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase RseC_MucC PF04246.7 KLO11149.1 - 0.0061 16.1 1.4 0.017 14.7 0.0 2.4 2 0 0 2 2 2 1 Positive regulator of sigma(E), RseC/MucC CoA_binding_3 PF13727.1 KLO11149.1 - 0.009 15.8 3.2 0.55 10.0 0.9 3.2 3 0 0 3 3 3 1 CoA-binding domain Lipid_DES PF08557.5 KLO11149.1 - 0.044 13.0 0.7 0.84 8.9 0.0 2.3 2 0 0 2 2 2 0 Sphingolipid Delta4-desaturase (DES) HAD_2 PF13419.1 KLO11149.1 - 0.11 12.6 0.1 0.54 10.4 0.0 2.0 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase SR-25 PF10500.4 KLO11150.1 - 0.0014 18.1 78.9 0.0014 18.1 54.7 2.3 1 1 1 2 2 2 1 Nuclear RNA-splicing-associated protein DUF2413 PF10310.4 KLO11150.1 - 1.4 7.6 21.3 2.3 6.9 14.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) Mem_trans PF03547.13 KLO11150.1 - 4.9 5.3 7.4 5.8 5.1 5.1 1.2 1 0 0 1 1 1 0 Membrane transport protein Zn_clus PF00172.13 KLO11151.1 - 1.9e-05 24.4 7.3 2.6e-05 24.0 5.0 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Zn_clus PF00172.13 KLO11152.1 - 7.1e-05 22.6 8.1 0.0001 22.1 5.6 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Zn_clus PF00172.13 KLO11153.1 - 3.1e-05 23.7 4.8 4.6e-05 23.2 3.3 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF1408 PF07193.6 KLO11153.1 - 0.13 11.7 0.0 0.16 11.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1408) Zn_clus PF00172.13 KLO11154.1 - 4.7e-07 29.6 14.3 4.7e-07 29.6 9.9 2.3 2 1 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF4596 PF15363.1 KLO11155.1 - 3.2 7.7 9.5 0.68 9.8 1.3 2.9 2 1 0 2 2 2 0 Domain of unknown function (DUF4596) RhoGEF PF00621.15 KLO11160.1 - 3.1e-34 118.4 0.0 5.6e-34 117.5 0.0 1.4 1 0 0 1 1 1 1 RhoGEF domain PspB PF06667.7 KLO11160.1 - 0.17 11.8 0.2 0.91 9.5 0.0 2.2 2 0 0 2 2 2 0 Phage shock protein B ATPgrasp_ST PF14397.1 KLO11164.1 - 0.072 12.1 0.0 0.092 11.8 0.0 1.1 1 0 0 1 1 1 0 Sugar-transfer associated ATP-grasp DUF1048 PF06304.6 KLO11164.1 - 0.079 13.2 0.0 0.15 12.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1048) Zn_clus PF00172.13 KLO11165.1 - 0.0003 20.6 8.3 0.0014 18.5 5.7 2.0 1 1 1 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-B_box PF00643.19 KLO11165.1 - 0.02 14.7 2.8 0.052 13.4 1.9 1.7 1 0 0 1 1 1 0 B-box zinc finger DUF3484 PF11983.3 KLO11165.1 - 0.3 11.9 2.3 0.5 11.2 0.2 2.4 3 1 0 3 3 3 0 Domain of unknown function (DUF3484) Zn_clus PF00172.13 KLO11166.1 - 7.4e-05 22.5 9.0 0.00015 21.5 6.2 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain LRR_adjacent PF08191.6 KLO11166.1 - 0.01 15.5 0.2 0.017 14.8 0.1 1.3 1 0 0 1 1 1 0 LRR adjacent Zn_clus PF00172.13 KLO11168.1 - 5e-07 29.5 10.6 7.1e-07 29.0 7.4 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Zn_clus PF00172.13 KLO11169.1 - 4.7e-07 29.6 9.5 9.5e-07 28.6 6.6 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Zn_clus PF00172.13 KLO11174.1 - 0.00024 20.9 10.8 0.00024 20.9 7.5 2.1 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HJURP_mid PF12346.3 KLO11174.1 - 2.8 8.1 8.3 36 4.5 0.0 2.6 2 0 0 2 2 2 0 Holliday junction recognition protein-associated repeat DUF2113 PF09886.4 KLO11175.1 - 0.1 11.7 0.0 0.28 10.2 0.0 1.6 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2113) DUF3959 PF13105.1 KLO11175.1 - 0.14 11.4 0.5 1.1 8.5 0.0 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3959) DUF3529 PF12046.3 KLO11175.1 - 0.17 10.8 0.8 0.32 9.9 0.3 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3529) DUF1129 PF06570.6 KLO11175.1 - 0.18 11.0 0.8 0.41 9.9 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1129) Ribosomal_S14 PF00253.16 KLO11176.1 - 0.0038 16.5 0.1 0.0077 15.5 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein S14p/S29e HMG_box PF00505.14 KLO11176.1 - 2.6 8.3 6.8 0.23 11.7 0.6 2.2 2 0 0 2 2 2 0 HMG (high mobility group) box DUF3584 PF12128.3 KLO11177.1 - 0.00078 16.9 13.0 0.0013 16.2 9.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) Wx5_PLAF3D7 PF09688.5 KLO11177.1 - 0.1 12.5 3.7 0.4 10.6 2.6 2.1 1 1 0 1 1 1 0 Protein of unknown function (Wx5_PLAF3D7) Sec8_exocyst PF04048.9 KLO11178.1 - 0.11 12.1 0.0 0.31 10.6 0.0 1.7 1 1 0 1 1 1 0 Sec8 exocyst complex component specific domain DUF4218 PF13960.1 KLO11180.1 - 0.032 13.6 0.3 0.055 12.9 0.2 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4218) PPTA PF01239.17 KLO11180.1 - 0.071 12.5 0.3 21 4.7 0.0 3.5 4 0 0 4 4 4 0 Protein prenyltransferase alpha subunit repeat Transposase_21 PF02992.9 KLO11181.1 - 9.4e-09 34.6 0.0 1.8e-08 33.7 0.0 1.4 1 0 0 1 1 1 1 Transposase family tnp2 TPR_10 PF13374.1 KLO11182.1 - 1.7 8.6 12.0 95 3.1 0.1 6.8 6 2 1 7 7 7 0 Tetratricopeptide repeat Adeno_E3 PF06040.6 KLO11182.1 - 7.1 6.5 10.2 30 4.5 0.0 4.0 2 1 2 5 5 5 0 Adenovirus E3 protein Zn_clus PF00172.13 KLO11184.1 - 5.2e-05 23.0 7.9 8.1e-05 22.4 5.5 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PPO1_DWL PF12142.3 KLO11189.1 - 0.082 12.4 1.1 0.35 10.4 0.1 2.3 2 0 0 2 2 2 0 Polyphenol oxidase middle domain YihI PF04220.7 KLO11193.1 - 0.55 9.5 7.6 1.4 8.1 0.7 3.0 1 1 2 3 3 3 0 Der GTPase activator (YihI) Aldo_ket_red PF00248.16 KLO11194.1 - 1e-64 218.0 0.2 1.2e-64 217.8 0.2 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Potex_coat PF06184.6 KLO11195.1 - 0.015 14.6 0.0 0.031 13.6 0.0 1.5 1 0 0 1 1 1 0 Potexvirus coat protein Pkinase PF00069.20 KLO11196.1 - 4e-46 157.2 0.0 5e-46 156.9 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KLO11196.1 - 3e-42 144.4 0.0 3.7e-42 144.1 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 KLO11196.1 - 0.057 12.4 0.1 0.2 10.7 0.0 1.7 1 1 1 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 KLO11196.1 - 0.06 12.2 0.1 0.37 9.7 0.1 1.9 1 1 0 1 1 1 0 Kinase-like BING4CT PF08149.6 KLO11201.1 - 3.6e-29 100.1 0.0 2.2e-28 97.5 0.0 2.3 2 0 0 2 2 2 1 BING4CT (NUC141) domain WD40 PF00400.27 KLO11201.1 - 1e-07 31.5 0.4 6.9e-07 28.9 0.0 2.7 3 0 0 3 3 3 1 WD domain, G-beta repeat YL1_C PF08265.6 KLO11202.1 - 1.2e-11 43.9 0.0 2e-11 43.2 0.0 1.4 1 0 0 1 1 1 1 YL1 nuclear protein C-terminal domain CDC27 PF09507.5 KLO11202.1 - 0.014 14.6 8.6 0.017 14.3 5.9 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 F-box-like PF12937.2 KLO11205.1 - 1.8e-05 24.3 0.0 5.5e-05 22.7 0.0 1.9 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KLO11205.1 - 0.032 13.8 0.2 7.9 6.2 0.0 2.9 2 0 0 2 2 2 0 F-box domain F-box-like PF12937.2 KLO11206.1 - 5.8e-07 29.1 4.2 1.7e-06 27.6 2.9 1.9 1 1 0 1 1 1 1 F-box-like F-box-like PF12937.2 KLO11207.1 - 1.4e-06 27.8 0.0 4.7e-06 26.2 0.0 1.9 1 0 0 1 1 1 1 F-box-like F-box-like PF12937.2 KLO11208.1 - 2e-06 27.4 0.1 6.2e-06 25.8 0.1 1.9 1 0 0 1 1 1 1 F-box-like Alpha-amylase PF00128.19 KLO11209.1 - 7e-104 347.6 0.5 1.1e-103 346.9 0.3 1.3 1 0 0 1 1 1 1 Alpha amylase, catalytic domain DUF3459 PF11941.3 KLO11209.1 - 0.00018 21.5 0.0 0.0005 20.1 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF3459) hDGE_amylase PF14701.1 KLO11209.1 - 0.0013 17.6 0.0 0.0025 16.7 0.0 1.3 1 0 0 1 1 1 1 glucanotransferase domain of human glycogen debranching enzyme F-box-like PF12937.2 KLO11210.1 - 6e-08 32.2 0.2 6e-08 32.2 0.1 2.3 3 0 0 3 3 3 1 F-box-like F-box-like PF12937.2 KLO11211.1 - 0.00097 18.8 1.8 0.0011 18.6 0.1 1.9 2 0 0 2 2 2 1 F-box-like F-box-like PF12937.2 KLO11212.1 - 0.0076 15.9 0.7 0.03 14.0 0.0 2.3 2 0 0 2 2 2 1 F-box-like LRR_8 PF13855.1 KLO11212.1 - 0.21 11.3 4.3 16 5.3 0.1 4.6 5 1 0 5 5 5 0 Leucine rich repeat F-box-like PF12937.2 KLO11214.1 - 4.4e-05 23.1 2.1 5e-05 22.9 0.2 2.1 2 0 0 2 2 2 1 F-box-like DUF2459 PF09601.5 KLO11214.1 - 0.074 12.7 0.0 0.15 11.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2459) LRR_8 PF13855.1 KLO11214.1 - 1.3 8.7 4.7 2.5 7.9 0.7 3.3 3 1 0 3 3 3 0 Leucine rich repeat F-box-like PF12937.2 KLO11215.1 - 0.0019 17.9 1.9 0.0025 17.5 0.0 2.2 3 0 0 3 3 3 1 F-box-like F-box-like PF12937.2 KLO11216.1 - 0.0064 16.1 0.6 0.11 12.1 0.0 2.9 2 0 0 2 2 2 1 F-box-like p450 PF00067.17 KLO11217.1 - 8.2e-54 182.8 0.0 1.1e-43 149.3 0.0 2.6 2 1 0 2 2 2 2 Cytochrome P450 PBP PF01161.15 KLO11218.1 - 1.6e-19 70.2 0.0 1.9e-19 69.9 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein F-box-like PF12937.2 KLO11219.1 - 5.6e-07 29.1 0.6 2.1e-06 27.3 0.4 2.0 1 0 0 1 1 1 1 F-box-like NUT_N PF12881.2 KLO11219.1 - 0.067 12.3 0.0 0.1 11.7 0.0 1.2 1 0 0 1 1 1 0 NUT protein N terminus F-box-like PF12937.2 KLO11220.1 - 0.00025 20.6 0.3 0.0032 17.1 0.0 2.7 2 0 0 2 2 2 1 F-box-like F-box-like PF12937.2 KLO11222.1 - 4.9e-05 22.9 3.1 0.00017 21.2 2.1 2.0 1 1 0 1 1 1 1 F-box-like LRR_8 PF13855.1 KLO11222.1 - 0.035 13.8 1.3 0.82 9.4 0.3 3.5 3 1 0 3 3 3 0 Leucine rich repeat LRR_7 PF13504.1 KLO11222.1 - 0.16 12.2 0.6 37 5.1 0.0 4.7 5 0 0 5 5 5 0 Leucine rich repeat LRR_4 PF12799.2 KLO11222.1 - 0.75 9.4 2.8 11 5.7 0.0 4.0 3 2 2 5 5 5 0 Leucine Rich repeats (2 copies) F-box-like PF12937.2 KLO11223.1 - 1.7e-05 24.4 0.1 6.6e-05 22.5 0.0 2.1 1 0 0 1 1 1 1 F-box-like LRR_8 PF13855.1 KLO11223.1 - 0.69 9.7 5.9 12 5.6 0.0 5.3 5 1 0 5 5 5 0 Leucine rich repeat F-box-like PF12937.2 KLO11224.1 - 2e-09 37.0 0.5 1.4e-08 34.2 0.2 2.6 3 0 0 3 3 3 1 F-box-like Cu_bind_like PF02298.12 KLO11227.1 - 0.00028 20.6 1.1 0.9 9.3 0.1 2.9 3 0 0 3 3 3 2 Plastocyanin-like domain Cupredoxin_1 PF13473.1 KLO11227.1 - 0.05 13.4 0.0 3.7 7.4 0.0 3.1 4 0 0 4 4 4 0 Cupredoxin-like domain DUF11 PF01345.13 KLO11227.1 - 0.29 11.2 4.2 6.5 6.8 0.1 2.9 3 0 0 3 3 3 0 Domain of unknown function DUF11 Polysacc_deac_1 PF01522.16 KLO11229.1 - 1.8e-25 88.9 0.0 1e-24 86.4 0.0 2.2 2 0 0 2 2 2 1 Polysaccharide deacetylase AAA PF00004.24 KLO11230.1 - 4.6e-17 62.4 0.0 1.1e-16 61.2 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 KLO11230.1 - 0.00067 19.3 0.0 0.0016 18.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 KLO11230.1 - 0.00083 19.5 0.8 0.0089 16.1 0.1 2.4 1 1 1 2 2 2 1 AAA domain AAA_18 PF13238.1 KLO11230.1 - 0.0042 17.4 0.0 0.027 14.7 0.0 2.3 2 0 0 2 2 2 1 AAA domain HTH_19 PF12844.2 KLO11230.1 - 0.0076 16.2 0.1 0.097 12.7 0.1 2.6 2 0 0 2 2 2 1 Helix-turn-helix domain Zeta_toxin PF06414.7 KLO11230.1 - 0.0095 15.0 0.0 0.024 13.7 0.0 1.6 1 0 0 1 1 1 1 Zeta toxin AAA_16 PF13191.1 KLO11230.1 - 0.019 14.9 0.2 0.057 13.3 0.1 1.9 1 1 0 1 1 1 0 AAA ATPase domain AAA_19 PF13245.1 KLO11230.1 - 0.031 14.0 0.1 0.072 12.8 0.1 1.5 1 0 0 1 1 1 0 Part of AAA domain AAA_17 PF13207.1 KLO11230.1 - 0.039 14.7 2.7 0.19 12.5 0.0 3.0 2 2 0 2 2 2 0 AAA domain NACHT PF05729.7 KLO11231.1 - 8.7e-11 41.7 0.0 1.9e-10 40.6 0.0 1.6 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 KLO11231.1 - 2.5e-06 27.5 0.0 2.2e-05 24.5 0.0 2.6 2 0 0 2 2 2 1 AAA ATPase domain Beta_helix PF13229.1 KLO11233.1 - 2e-09 37.4 29.3 6.2e-08 32.5 16.1 3.4 1 1 1 2 2 2 2 Right handed beta helix region Myc_target_1 PF15179.1 KLO11233.1 - 0.032 13.8 0.1 0.064 12.8 0.1 1.5 1 0 0 1 1 1 0 Myc target protein 1 Baculo_E56 PF04639.7 KLO11233.1 - 0.033 12.8 0.0 0.098 11.2 0.0 1.7 2 0 0 2 2 2 0 Baculoviral E56 protein, specific to ODV envelope PAP_central PF04928.12 KLO11234.1 - 1.8e-103 344.7 0.0 2.4e-103 344.3 0.0 1.1 1 0 0 1 1 1 1 Poly(A) polymerase central domain PAP_RNA-bind PF04926.10 KLO11234.1 - 3.9e-44 149.9 0.0 6.4e-44 149.2 0.0 1.4 1 0 0 1 1 1 1 Poly(A) polymerase predicted RNA binding domain NTP_transf_2 PF01909.18 KLO11234.1 - 5.5e-08 33.0 0.0 1.3e-07 31.7 0.0 1.7 1 0 0 1 1 1 1 Nucleotidyltransferase domain DNA_pol_B_palm PF14792.1 KLO11234.1 - 0.011 15.7 0.0 0.25 11.4 0.0 2.8 3 0 0 3 3 3 0 DNA polymerase beta palm Nrap PF03813.9 KLO11234.1 - 0.16 9.5 0.3 0.48 7.8 0.0 1.8 2 0 0 2 2 2 0 Nrap protein Cys_Met_Meta_PP PF01053.15 KLO11235.1 - 2.6e-59 200.4 0.0 6.2e-59 199.2 0.0 1.6 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme IBN_N PF03810.14 KLO11237.1 - 1.7e-06 27.8 0.1 0.0013 18.5 0.1 2.8 2 0 0 2 2 2 2 Importin-beta N-terminal domain Xpo1 PF08389.7 KLO11237.1 - 0.0044 16.9 0.0 0.021 14.7 0.0 2.2 2 0 0 2 2 2 1 Exportin 1-like protein Pex2_Pex12 PF04757.9 KLO11238.1 - 1.3e-29 103.2 4.5 1.8e-29 102.7 3.1 1.2 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4 PF00097.20 KLO11238.1 - 0.085 12.5 2.9 0.55 9.9 2.0 2.1 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KLO11238.1 - 0.09 12.6 4.1 0.63 9.9 0.9 2.4 2 0 0 2 2 2 0 Ring finger domain zf-C3HC4_2 PF13923.1 KLO11238.1 - 0.71 9.9 3.5 0.52 10.3 0.5 2.1 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Mur_ligase_M PF08245.7 KLO11239.1 - 9.9e-06 25.7 0.0 0.00059 19.9 0.0 2.9 1 1 0 1 1 1 1 Mur ligase middle domain Slx4 PF09494.5 KLO11240.1 - 2.1e-08 33.7 0.0 5.2e-08 32.5 0.0 1.7 1 0 0 1 1 1 1 Slx4 endonuclease Vps52 PF04129.7 KLO11242.1 - 2.1e-67 227.8 0.6 7.3e-44 150.1 0.1 3.0 2 1 0 2 2 2 2 Vps52 / Sac2 family Sec3_C PF09763.4 KLO11242.1 - 5.9e-06 24.7 0.5 5.9e-06 24.7 0.4 2.0 1 1 1 2 2 2 1 Exocyst complex component Sec3 F-box-like PF12937.2 KLO11244.1 - 1.2e-05 24.9 0.1 3.3e-05 23.5 0.1 1.8 1 1 0 1 1 1 1 F-box-like F-box-like PF12937.2 KLO11246.1 - 2.5e-08 33.4 1.6 2.5e-08 33.4 1.1 2.1 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 KLO11246.1 - 0.00043 19.8 0.7 0.0024 17.4 0.5 2.2 1 1 0 1 1 1 1 F-box domain DUF4027 PF13219.1 KLO11246.1 - 0.077 12.4 0.1 0.15 11.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4027) F-box-like PF12937.2 KLO11247.1 - 0.022 14.4 3.1 0.16 11.6 2.2 2.4 1 1 0 1 1 1 0 F-box-like LRR_7 PF13504.1 KLO11248.1 - 0.13 12.5 0.4 2.9e+02 2.4 0.0 4.7 5 0 0 5 5 5 0 Leucine rich repeat LRR_4 PF12799.2 KLO11248.1 - 0.29 10.8 7.3 1.6 8.4 0.5 3.7 4 0 0 4 4 4 0 Leucine Rich repeats (2 copies) cNMP_binding PF00027.24 KLO11249.1 - 1.9e-39 133.3 0.0 1.7e-18 66.1 0.0 2.5 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain RIIa PF02197.12 KLO11249.1 - 8.6e-11 41.0 0.2 2e-10 39.8 0.1 1.6 1 0 0 1 1 1 1 Regulatory subunit of type II PKA R-subunit fn3 PF00041.16 KLO11250.1 - 0.011 15.8 0.0 3.6 7.7 0.0 3.4 3 0 0 3 3 3 0 Fibronectin type III domain Drc1-Sld2 PF11719.3 KLO11250.1 - 0.041 12.9 3.8 0.081 12.0 2.7 1.4 1 0 0 1 1 1 0 DNA replication and checkpoint protein Pkinase_Tyr PF07714.12 KLO11251.1 - 9.9e-31 106.7 0.0 1.1e-30 106.5 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 KLO11251.1 - 7e-30 104.0 0.0 7.7e-30 103.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.18 KLO11251.1 - 0.00054 19.7 0.0 0.0009 19.0 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.1 KLO11251.1 - 0.0017 17.3 0.0 0.002 17.1 0.0 1.1 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.17 KLO11251.1 - 0.0043 16.4 0.0 0.0079 15.5 0.0 1.4 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.9 KLO11251.1 - 0.013 14.5 0.0 0.02 13.9 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Ribosomal_S11 PF00411.14 KLO11252.1 - 4.4e-09 36.4 1.2 1.4e-08 34.8 0.8 1.8 1 1 0 1 1 1 1 Ribosomal protein S11 UCR_UQCRX_QCR9 PF05365.7 KLO11253.1 - 4.2e-28 96.7 3.7 4.6e-28 96.6 2.5 1.0 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase, UQCRX/QCR9 like IPK PF03770.11 KLO11254.1 - 4.2e-52 176.6 0.0 8.1e-52 175.7 0.0 1.5 1 0 0 1 1 1 1 Inositol polyphosphate kinase ECR1_N PF14382.1 KLO11256.1 - 2.2e-15 55.6 0.1 3.8e-15 54.8 0.1 1.4 1 0 0 1 1 1 1 Exosome complex exonuclease RRP4 N-terminal region EXOSC1 PF10447.4 KLO11256.1 - 0.0054 16.6 0.0 0.21 11.5 0.0 2.5 1 1 0 1 1 1 1 Exosome component EXOSC1/CSL4 F-box-like PF12937.2 KLO11257.1 - 0.00069 19.2 6.1 0.0038 16.9 2.6 2.9 2 1 0 2 2 2 1 F-box-like DNA_methylase PF00145.12 KLO11258.1 - 8.2e-24 84.3 0.0 7.1e-23 81.2 0.0 2.1 1 1 0 1 1 1 1 C-5 cytosine-specific DNA methylase fn3 PF00041.16 KLO11258.1 - 0.00064 19.7 6.8 3 8.0 0.5 4.6 4 0 0 4 4 4 3 Fibronectin type III domain Methyltransf_15 PF09445.5 KLO11258.1 - 0.0068 15.9 0.0 0.014 14.9 0.0 1.4 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Methyltransf_26 PF13659.1 KLO11258.1 - 0.029 14.4 0.0 0.12 12.4 0.0 2.1 1 0 0 1 1 1 0 Methyltransferase domain Pkinase PF00069.20 KLO11260.1 - 3.1e-68 229.7 0.0 4.1e-68 229.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KLO11260.1 - 1.2e-29 103.2 0.0 1.6e-29 102.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.19 KLO11260.1 - 6.1e-13 49.0 1.0 6.1e-13 49.0 0.7 2.5 2 1 0 2 2 2 1 Protein kinase C terminal domain Kinase-like PF14531.1 KLO11260.1 - 1.7e-07 30.5 0.0 4.2e-07 29.2 0.0 1.6 1 1 0 2 2 2 1 Kinase-like C2 PF00168.25 KLO11260.1 - 1e-06 28.4 0.1 0.0051 16.6 0.1 2.6 2 0 0 2 2 2 2 C2 domain APH PF01636.18 KLO11260.1 - 0.018 14.7 0.0 0.036 13.7 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.9 KLO11260.1 - 0.033 13.2 0.0 0.068 12.2 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Suc_Fer-like PF06999.7 KLO11261.1 - 9.9e-33 114.0 0.0 2.2e-32 112.9 0.0 1.5 1 1 0 1 1 1 1 Sucrase/ferredoxin-like Ribosomal_S18 PF01084.15 KLO11262.1 - 3.8e-14 52.2 0.2 8.4e-14 51.1 0.1 1.6 1 0 0 1 1 1 1 Ribosomal protein S18 UBN2_3 PF14244.1 KLO11263.1 - 1.8e-06 27.6 0.7 3.1e-05 23.5 0.2 2.1 1 1 1 2 2 2 1 gag-polypeptide of LTR copia-type UBN2 PF14223.1 KLO11263.1 - 0.00035 20.3 0.1 0.00054 19.7 0.0 1.3 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type UBN2_2 PF14227.1 KLO11263.1 - 0.019 14.4 0.1 0.038 13.5 0.1 1.5 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type Pkinase PF00069.20 KLO11264.1 - 4.1e-56 190.0 0.0 1.2e-55 188.4 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KLO11264.1 - 2.2e-27 95.7 0.0 9.1e-20 70.8 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 KLO11264.1 - 0.00035 19.6 0.4 0.0018 17.2 0.0 2.1 3 0 0 3 3 3 1 Kinase-like APH PF01636.18 KLO11264.1 - 0.00048 19.9 0.9 0.016 14.9 0.0 2.6 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.9 KLO11264.1 - 0.01 14.9 0.0 0.024 13.7 0.0 1.6 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 KLO11264.1 - 0.069 12.4 0.0 0.15 11.3 0.0 1.5 1 0 0 1 1 1 0 RIO1 family MFS_1 PF07690.11 KLO11265.1 - 4.5e-13 48.6 31.2 4.5e-13 48.6 21.6 1.7 1 1 1 2 2 2 1 Major Facilitator Superfamily UNC-93 PF05978.11 KLO11265.1 - 1e-12 47.8 4.9 1e-12 47.8 3.4 2.2 3 0 0 3 3 3 1 Ion channel regulatory protein UNC-93 DUF2422 PF10337.4 KLO11265.1 - 5.3 5.7 6.8 0.39 9.4 1.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2422) TB2_DP1_HVA22 PF03134.14 KLO11266.1 - 1.5e-26 91.9 4.8 2.4e-26 91.3 3.3 1.3 1 0 0 1 1 1 1 TB2/DP1, HVA22 family PgaD PF13994.1 KLO11266.1 - 0.55 9.7 4.2 0.78 9.2 1.2 2.0 1 1 1 2 2 2 0 PgaD-like protein UPF0197 PF05251.7 KLO11267.1 - 3.1e-06 27.4 3.5 4.1e-06 26.9 2.4 1.2 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0197) DUF2721 PF11026.3 KLO11267.1 - 1.7 8.2 5.4 2.1 8.0 3.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2721) TFIIS_C PF01096.13 KLO11268.1 - 1.2e-16 59.9 0.7 1.2e-16 59.9 0.5 3.0 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.11 KLO11268.1 - 3.8e-07 29.6 0.3 3.8e-07 29.6 0.2 2.6 3 0 0 3 3 3 1 RNA polymerases M/15 Kd subunit DZR PF12773.2 KLO11268.1 - 1.2e-06 28.1 4.3 0.00033 20.3 0.1 2.5 2 1 0 2 2 2 2 Double zinc ribbon zinc_ribbon_5 PF13719.1 KLO11268.1 - 0.00051 19.5 5.8 0.86 9.2 0.2 3.8 3 1 0 3 3 3 1 zinc-ribbon domain Zn_Tnp_IS1595 PF12760.2 KLO11268.1 - 0.00057 19.6 8.3 0.00092 18.9 0.3 3.1 2 1 1 3 3 3 1 Transposase zinc-ribbon domain PhnA_Zn_Ribbon PF08274.7 KLO11268.1 - 0.00064 19.4 4.7 0.17 11.7 0.0 3.3 2 2 0 2 2 2 1 PhnA Zinc-Ribbon Baculo_LEF5_C PF11792.3 KLO11268.1 - 0.00086 18.6 0.7 0.00086 18.6 0.5 2.3 2 0 0 2 2 2 1 Baculoviridae late expression factor 5 C-terminal domain zinc_ribbon_2 PF13240.1 KLO11268.1 - 0.0011 18.3 8.8 0.03 13.8 1.8 3.4 3 1 0 3 3 3 1 zinc-ribbon domain IBR PF01485.16 KLO11268.1 - 0.0019 17.9 6.3 0.024 14.5 0.0 2.6 2 1 0 2 2 2 1 IBR domain zinc_ribbon_4 PF13717.1 KLO11268.1 - 0.0021 17.7 7.3 1.9 8.2 0.3 3.9 3 1 0 3 3 3 1 zinc-ribbon domain zf-ribbon_3 PF13248.1 KLO11268.1 - 0.0026 16.9 13.5 0.044 12.9 2.8 3.5 3 1 1 4 4 4 2 zinc-ribbon domain DUF2387 PF09526.5 KLO11268.1 - 0.0028 17.5 5.9 0.42 10.5 0.2 2.6 1 1 1 2 2 2 2 Probable metal-binding protein (DUF2387) UPF0547 PF10571.4 KLO11268.1 - 0.0035 16.9 8.8 0.98 9.1 0.2 3.6 3 1 0 3 3 3 2 Uncharacterised protein family UPF0547 OrfB_Zn_ribbon PF07282.6 KLO11268.1 - 0.0064 16.1 7.2 0.37 10.4 0.1 2.7 2 2 0 2 2 2 1 Putative transposase DNA-binding domain TF_Zn_Ribbon PF08271.7 KLO11268.1 - 0.0084 15.4 11.3 0.023 14.0 1.9 2.8 2 2 0 2 2 2 1 TFIIB zinc-binding DNA_ligase_ZBD PF03119.11 KLO11268.1 - 0.011 15.4 2.5 1.1 8.9 0.0 2.5 2 0 0 2 2 2 0 NAD-dependent DNA ligase C4 zinc finger domain Elf1 PF05129.8 KLO11268.1 - 0.014 15.0 1.1 0.014 15.0 0.8 2.4 2 1 0 2 2 2 0 Transcription elongation factor Elf1 like Lar_restr_allev PF14354.1 KLO11268.1 - 0.017 15.4 7.3 0.39 11.0 0.3 3.0 2 1 0 2 2 2 0 Restriction alleviation protein Lar FdhE PF04216.7 KLO11268.1 - 0.017 14.8 0.5 0.017 14.8 0.4 1.6 2 0 0 2 2 1 0 Protein involved in formate dehydrogenase formation DNA_RNApol_7kD PF03604.8 KLO11268.1 - 0.02 14.3 5.9 0.026 13.9 0.2 2.9 3 0 0 3 3 3 0 DNA directed RNA polymerase, 7 kDa subunit SRCR_2 PF15494.1 KLO11268.1 - 0.036 14.3 3.2 0.082 13.1 0.2 2.2 1 1 1 2 2 2 0 Scavenger receptor cysteine-rich domain zf-ISL3 PF14690.1 KLO11268.1 - 0.1 12.6 2.2 16 5.6 0.1 3.5 3 1 0 3 3 3 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 HypA PF01155.14 KLO11268.1 - 0.18 11.4 5.7 0.65 9.6 0.1 2.7 2 1 0 3 3 3 0 Hydrogenase expression/synthesis hypA family DUF164 PF02591.10 KLO11268.1 - 0.21 11.4 3.7 18 5.2 0.0 3.5 4 0 0 4 4 4 0 Putative zinc ribbon domain zf-LSD1 PF06943.7 KLO11268.1 - 0.25 10.9 0.1 0.25 10.9 0.1 2.7 3 0 0 3 3 3 0 LSD1 zinc finger PHD PF00628.24 KLO11268.1 - 0.29 10.8 8.1 2.6 7.8 0.4 2.8 2 1 1 3 3 3 0 PHD-finger zf-LITAF-like PF10601.4 KLO11268.1 - 0.45 10.4 5.0 2.7 7.9 0.4 3.1 3 1 0 3 3 3 0 LITAF-like zinc ribbon domain zf-CSL PF05207.8 KLO11268.1 - 0.5 9.9 8.5 0.16 11.4 0.3 2.4 2 1 0 2 2 2 0 CSL zinc finger zf-RING_3 PF14369.1 KLO11268.1 - 0.51 10.3 10.9 61 3.7 0.1 4.0 3 1 1 4 4 4 0 zinc-finger RRN7 PF11781.3 KLO11268.1 - 0.58 9.7 3.8 49 3.5 0.1 3.7 4 0 0 4 4 4 0 RNA polymerase I-specific transcription initiation factor Rrn7 zf-C4_Topoisom PF01396.14 KLO11268.1 - 0.72 9.4 7.2 8.5 5.9 0.2 3.4 3 0 0 3 3 3 0 Topoisomerase DNA binding C4 zinc finger zinc-ribbons_6 PF07191.7 KLO11268.1 - 1 9.1 6.5 1.6 8.5 0.1 2.4 2 1 0 2 2 2 0 zinc-ribbons Zn-ribbon_8 PF09723.5 KLO11268.1 - 1.2 9.1 14.5 3.3 7.7 0.3 3.8 2 2 2 4 4 4 0 Zinc ribbon domain zf-DNL PF05180.7 KLO11268.1 - 1.2 8.8 5.4 1.1 9.0 0.5 2.8 3 0 0 3 3 3 0 DNL zinc finger Nudix_N_2 PF14803.1 KLO11268.1 - 1.3 8.8 13.7 0.58 9.9 2.0 3.5 3 1 0 3 3 3 0 Nudix N-terminal zf-C2H2_3 PF13878.1 KLO11268.1 - 1.6 8.3 0.0 1.6 8.3 0.0 3.0 4 0 0 4 4 2 0 zinc-finger of acetyl-transferase ESCO A2L_zn_ribbon PF08792.5 KLO11268.1 - 1.8 8.1 11.4 2.7 7.5 0.1 3.7 5 0 0 5 5 3 0 A2L zinc ribbon domain DUF2082 PF09855.4 KLO11268.1 - 2 8.3 7.4 2.3 8.1 0.2 2.9 2 2 1 3 3 2 0 Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082) GFA PF04828.9 KLO11268.1 - 2.4 8.1 9.3 4.1 7.4 0.5 2.7 1 1 1 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme DUF1451 PF07295.6 KLO11268.1 - 3 7.6 6.0 8 6.2 1.4 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF1451) Opy2 PF09463.5 KLO11268.1 - 4.6 7.4 10.1 14 5.8 0.1 3.9 4 0 0 4 4 4 0 Opy2 protein CpXC PF14353.1 KLO11268.1 - 5.2 7.0 9.3 15 5.5 1.2 3.5 1 1 1 3 3 3 0 CpXC protein zf-trcl PF13451.1 KLO11268.1 - 5.6 6.6 8.8 5.9 6.6 0.6 3.6 3 1 0 3 3 3 0 Probable zinc-binding domain Auto_anti-p27 PF06677.7 KLO11268.1 - 7.4 6.4 10.5 29 4.5 0.1 3.8 4 0 0 4 4 4 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) CENP-N PF05238.8 KLO11269.1 - 0.036 13.1 1.1 0.054 12.5 0.7 1.3 1 1 0 1 1 1 0 Kinetochore protein CHL4 like GTSE1_N PF15259.1 KLO11269.1 - 0.05 13.5 0.4 0.1 12.5 0.3 1.5 1 0 0 1 1 1 0 G-2 and S-phase expressed 1 Peptidase_M1 PF01433.15 KLO11270.1 - 2.8e-59 201.1 0.0 3.7e-59 200.7 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M1 Leuk-A4-hydro_C PF09127.6 KLO11270.1 - 1.1e-32 112.6 0.0 2.1e-32 111.7 0.0 1.5 1 0 0 1 1 1 1 Leukotriene A4 hydrolase, C-terminal Peptidase_MA_2 PF13485.1 KLO11270.1 - 9e-14 51.6 0.0 2e-13 50.5 0.0 1.6 1 0 0 1 1 1 1 Peptidase MA superfamily Peptidase_M61 PF05299.7 KLO11270.1 - 0.019 14.9 1.4 0.32 10.9 1.0 2.3 1 1 0 1 1 1 0 M61 glycyl aminopeptidase Peptidase_M1 PF01433.15 KLO11271.1 - 1.1e-59 202.4 0.0 1.6e-59 202.0 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M1 Leuk-A4-hydro_C PF09127.6 KLO11271.1 - 8.9e-28 96.6 0.0 2.2e-27 95.3 0.0 1.7 1 0 0 1 1 1 1 Leukotriene A4 hydrolase, C-terminal Peptidase_MA_2 PF13485.1 KLO11271.1 - 2e-13 50.4 0.0 4.7e-13 49.2 0.0 1.7 1 0 0 1 1 1 1 Peptidase MA superfamily Peptidase_M61 PF05299.7 KLO11271.1 - 0.05 13.5 1.6 0.7 9.8 1.1 2.3 1 1 0 1 1 1 0 M61 glycyl aminopeptidase ArfGap PF01412.13 KLO11272.1 - 1.1e-40 138.0 0.4 1.7e-40 137.4 0.3 1.3 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf NMD3 PF04981.8 KLO11272.1 - 0.051 12.6 0.2 0.071 12.2 0.1 1.1 1 0 0 1 1 1 0 NMD3 family Oxysterol_BP PF01237.13 KLO11274.1 - 9.1e-86 287.5 0.0 1.1e-85 287.2 0.0 1.0 1 0 0 1 1 1 1 Oxysterol-binding protein Erf4 PF10256.4 KLO11275.1 - 3.3e-27 94.7 0.1 4.5e-27 94.2 0.0 1.2 1 0 0 1 1 1 1 Golgin subfamily A member 7/ERF4 family TPR_1 PF00515.23 KLO11276.1 - 6.1e-53 174.3 23.1 8.9e-08 31.4 0.0 10.5 11 1 0 11 11 11 9 Tetratricopeptide repeat TPR_2 PF07719.12 KLO11276.1 - 3.7e-50 163.8 15.5 3.6e-05 23.3 0.0 10.2 11 0 0 11 11 11 9 Tetratricopeptide repeat TPR_11 PF13414.1 KLO11276.1 - 8.3e-50 166.3 15.3 2.5e-11 43.0 0.1 6.5 3 2 2 6 6 6 6 TPR repeat TPR_8 PF13181.1 KLO11276.1 - 2.2e-36 120.9 15.6 0.0016 18.0 1.8 10.2 8 1 2 10 10 10 8 Tetratricopeptide repeat TPR_12 PF13424.1 KLO11276.1 - 1.7e-31 107.9 17.1 6.7e-08 32.3 0.0 6.6 2 2 5 7 7 7 6 Tetratricopeptide repeat TPR_14 PF13428.1 KLO11276.1 - 3.8e-30 101.6 4.0 0.0034 17.8 0.0 9.4 4 3 5 9 9 9 7 Tetratricopeptide repeat TPR_16 PF13432.1 KLO11276.1 - 2.5e-29 101.2 11.1 5.1e-05 23.8 0.0 7.4 4 2 3 7 7 7 7 Tetratricopeptide repeat TPR_17 PF13431.1 KLO11276.1 - 1.5e-28 96.5 14.6 0.00059 19.8 0.0 10.5 11 0 0 11 11 11 5 Tetratricopeptide repeat TPR_7 PF13176.1 KLO11276.1 - 1.1e-25 87.2 8.1 0.034 13.9 0.2 9.7 9 0 0 9 9 9 6 Tetratricopeptide repeat TPR_6 PF13174.1 KLO11276.1 - 4.7e-24 83.1 9.6 0.046 14.1 0.0 10.0 10 0 0 10 10 10 6 Tetratricopeptide repeat TPR_19 PF14559.1 KLO11276.1 - 1.7e-23 82.7 13.6 5.8e-06 26.5 0.1 6.8 5 2 1 7 7 7 5 Tetratricopeptide repeat Apc3 PF12895.2 KLO11276.1 - 8.2e-12 45.1 11.3 2.1e-05 24.5 1.3 4.3 5 0 0 5 5 4 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.1 KLO11276.1 - 9.6e-11 41.3 13.0 0.02 14.7 0.0 5.4 5 1 1 6 6 5 5 Tetratricopeptide repeat TPR_15 PF13429.1 KLO11276.1 - 4.4e-09 35.8 3.3 0.00078 18.5 0.9 4.8 1 1 3 5 5 5 2 Tetratricopeptide repeat TPR_21 PF09976.4 KLO11276.1 - 8.7e-05 22.4 6.3 0.83 9.5 0.2 3.8 3 1 0 3 3 3 2 Tetratricopeptide repeat SNAP PF14938.1 KLO11276.1 - 0.00017 20.8 6.0 3 6.9 0.0 4.2 1 1 3 4 4 4 2 Soluble NSF attachment protein, SNAP TPR_20 PF14561.1 KLO11276.1 - 0.00064 19.7 0.5 0.18 11.9 0.0 3.9 3 1 1 4 4 4 1 Tetratricopeptide repeat DUF2225 PF09986.4 KLO11276.1 - 0.0055 16.1 1.2 2.2 7.7 0.0 3.0 2 1 0 3 3 3 1 Uncharacterized protein conserved in bacteria (DUF2225) MIT PF04212.13 KLO11276.1 - 0.026 14.3 14.7 17 5.4 1.2 6.0 7 0 0 7 7 6 0 MIT (microtubule interacting and transport) domain TPR_3 PF07720.7 KLO11276.1 - 0.11 12.3 17.5 0.58 10.0 0.3 5.5 6 0 0 6 6 6 0 Tetratricopeptide repeat ChAPs PF09295.5 KLO11276.1 - 0.11 11.2 0.1 6.4 5.4 0.0 2.4 3 0 0 3 3 3 0 ChAPs (Chs5p-Arf1p-binding proteins) RPN7 PF10602.4 KLO11276.1 - 0.13 11.6 5.0 6.7 6.0 0.0 4.3 4 2 2 6 6 6 0 26S proteasome subunit RPN7 DUF627 PF04781.7 KLO11276.1 - 0.69 9.5 0.5 2.2 7.9 0.3 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF627) TT_ORF1 PF02956.9 KLO11276.1 - 1.4 7.3 5.4 2.7 6.3 3.7 1.4 1 0 0 1 1 1 0 TT viral orf 1 4F5 PF04419.9 KLO11280.1 - 2.3e-08 34.6 13.9 2.3e-08 34.6 9.6 2.2 2 1 0 2 2 2 1 4F5 protein family Dishevelled PF02377.10 KLO11280.1 - 1 9.6 5.7 0.27 11.4 1.3 1.8 1 1 1 2 2 2 0 Dishevelled specific domain ATP11 PF06644.6 KLO11280.1 - 6.2 6.2 7.6 6.4 6.1 5.3 1.0 1 0 0 1 1 1 0 ATP11 protein PAM2 PF07145.10 KLO11282.1 - 0.0015 17.8 5.5 2.1 8.0 0.1 4.3 4 0 0 4 4 4 3 Ataxin-2 C-terminal region DNA_topoisoIV PF00521.15 KLO11283.1 - 1.1e-122 409.9 1.1 1.4e-122 409.5 0.0 1.7 2 0 0 2 2 2 1 DNA gyrase/topoisomerase IV, subunit A DNA_gyraseB PF00204.20 KLO11283.1 - 4.4e-36 123.7 2.3 1.2e-35 122.3 1.6 1.7 1 0 0 1 1 1 1 DNA gyrase B Toprim PF01751.17 KLO11283.1 - 1.6e-14 53.6 0.0 5.4e-14 51.9 0.0 1.9 1 0 0 1 1 1 1 Toprim domain HATPase_c PF02518.21 KLO11283.1 - 8.5e-08 31.8 0.0 2.2e-07 30.5 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF442 PF04273.8 KLO11283.1 - 0.049 13.4 0.0 0.13 12.1 0.0 1.7 1 0 0 1 1 1 0 Putative phosphatase (DUF442) GFO_IDH_MocA PF01408.17 KLO11284.1 - 8.2e-18 65.0 0.1 1.4e-17 64.2 0.1 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 KLO11284.1 - 2.9e-15 56.0 0.3 8.8e-15 54.5 0.2 1.8 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain Semialdhyde_dh PF01118.19 KLO11284.1 - 0.013 15.7 0.0 0.029 14.6 0.0 1.5 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain NAD_binding_3 PF03447.11 KLO11284.1 - 0.037 14.4 0.1 0.072 13.4 0.0 1.5 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain DEAD PF00270.24 KLO11285.1 - 8.3e-44 149.0 0.0 1.5e-43 148.1 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KLO11285.1 - 6.2e-26 90.0 0.0 1.4e-24 85.7 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 KLO11285.1 - 0.00041 20.2 0.1 0.0028 17.4 0.0 2.2 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_22 PF13401.1 KLO11285.1 - 0.058 13.5 0.2 0.37 10.9 0.1 2.3 1 1 0 1 1 1 0 AAA domain FAD_binding_3 PF01494.14 KLO11286.1 - 1.9e-17 63.3 0.0 1.8e-16 60.1 0.0 2.0 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 KLO11286.1 - 0.0045 16.9 0.1 0.014 15.4 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain SE PF08491.5 KLO11286.1 - 0.018 13.9 0.0 0.025 13.4 0.0 1.2 1 0 0 1 1 1 0 Squalene epoxidase DAO PF01266.19 KLO11286.1 - 0.085 11.7 0.7 0.37 9.6 0.5 2.0 1 1 0 1 1 1 0 FAD dependent oxidoreductase Trp_halogenase PF04820.9 KLO11286.1 - 0.11 11.1 0.4 0.25 9.9 0.0 1.8 3 0 0 3 3 3 0 Tryptophan halogenase FAD_binding_3 PF01494.14 KLO11287.1 - 4.6e-23 81.8 0.0 3.7e-22 78.8 0.0 1.9 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 KLO11287.1 - 8.2e-05 21.6 0.1 0.047 12.5 0.0 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KLO11287.1 - 0.0016 18.4 0.2 0.0047 16.9 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain SE PF08491.5 KLO11287.1 - 0.0036 16.1 0.0 0.0055 15.5 0.0 1.4 1 0 0 1 1 1 1 Squalene epoxidase Trp_halogenase PF04820.9 KLO11287.1 - 0.0056 15.3 1.0 0.14 10.7 0.0 2.5 3 0 0 3 3 3 1 Tryptophan halogenase Pyr_redox PF00070.22 KLO11287.1 - 0.0059 16.9 0.2 0.28 11.6 0.1 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 KLO11287.1 - 0.041 13.6 0.1 0.51 10.1 0.0 2.3 1 1 0 1 1 1 0 FAD-NAD(P)-binding FAD_binding_3 PF01494.14 KLO11288.1 - 1.3e-22 80.3 0.0 2.7e-10 39.8 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.19 KLO11288.1 - 0.14 11.0 3.1 0.65 8.8 2.1 1.9 2 0 0 2 2 2 0 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 KLO11289.1 - 2.3e-24 86.1 0.0 2.2e-23 82.9 0.0 1.9 1 1 0 1 1 1 1 FAD binding domain Trp_halogenase PF04820.9 KLO11289.1 - 0.0023 16.6 0.1 0.073 11.6 0.0 2.5 2 1 0 3 3 3 1 Tryptophan halogenase NAD_binding_8 PF13450.1 KLO11289.1 - 0.0064 16.4 0.3 0.017 15.1 0.2 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 KLO11289.1 - 0.021 14.6 0.0 6.3 6.5 0.0 2.4 2 0 0 2 2 2 0 FAD-NAD(P)-binding DAO PF01266.19 KLO11289.1 - 0.022 13.6 0.4 0.58 8.9 0.8 2.2 1 1 0 2 2 2 0 FAD dependent oxidoreductase SE PF08491.5 KLO11289.1 - 0.028 13.2 0.0 0.051 12.3 0.0 1.3 1 0 0 1 1 1 0 Squalene epoxidase DUF2934 PF11154.3 KLO11289.1 - 0.11 11.8 0.2 0.23 10.8 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2934) BAR PF03114.13 KLO11290.1 - 4.4e-39 134.3 0.5 7.3e-39 133.6 0.4 1.3 1 0 0 1 1 1 1 BAR domain SH3_1 PF00018.23 KLO11290.1 - 5.3e-15 54.5 0.1 9.6e-15 53.7 0.1 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 KLO11290.1 - 6.2e-15 54.5 0.2 1.1e-14 53.7 0.1 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 KLO11290.1 - 3e-09 36.2 0.1 5.2e-09 35.4 0.1 1.4 1 0 0 1 1 1 1 Variant SH3 domain Vps5 PF09325.5 KLO11290.1 - 0.0002 20.6 0.5 0.00075 18.8 0.4 1.9 1 1 0 1 1 1 1 Vps5 C terminal like SBDS PF01172.13 KLO11291.1 - 1.7e-32 111.0 2.5 2.9e-32 110.3 1.7 1.4 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein SBDS_C PF09377.5 KLO11291.1 - 7.3e-30 103.2 0.5 1.4e-29 102.3 0.4 1.5 1 0 0 1 1 1 1 SBDS protein C-terminal domain Nup96 PF12110.3 KLO11292.1 - 0.0094 15.0 0.1 0.032 13.3 0.0 1.7 2 0 0 2 2 2 1 Nuclear protein 96 Pertus-S4-tox PF09275.5 KLO11293.1 - 0.13 12.3 0.0 0.21 11.7 0.0 1.3 1 0 0 1 1 1 0 Pertussis toxin S4 subunit SAP30_Sin3_bdg PF13867.1 KLO11295.1 - 3.3e-06 26.8 0.1 7.5e-06 25.7 0.0 1.6 1 0 0 1 1 1 1 Sin3 binding region of histone deacetylase complex subunit SAP30 Med3 PF11593.3 KLO11295.1 - 0.0042 16.3 14.4 0.0064 15.7 10.0 1.3 1 0 0 1 1 1 1 Mediator complex subunit 3 fungal Chorismate_synt PF01264.16 KLO11296.1 - 1.1e-133 444.9 0.1 1.5e-133 444.6 0.0 1.1 1 0 0 1 1 1 1 Chorismate synthase Nfu_N PF08712.6 KLO11297.1 - 7.2e-31 105.6 0.0 1.9e-30 104.3 0.0 1.7 2 0 0 2 2 2 1 Scaffold protein Nfu/NifU N terminal NifU PF01106.12 KLO11297.1 - 1.2e-21 76.2 0.2 2.2e-21 75.4 0.1 1.5 1 0 0 1 1 1 1 NifU-like domain Glyco_trans_1_4 PF13692.1 KLO11298.1 - 1.2e-16 61.1 0.0 2.2e-16 60.2 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.1 KLO11298.1 - 9.9e-05 22.5 0.0 0.00021 21.4 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glycos_transf_1 PF00534.15 KLO11298.1 - 0.0001 21.7 0.0 0.00017 21.0 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.1 KLO11298.1 - 0.11 12.7 0.0 0.26 11.5 0.0 1.6 1 0 0 1 1 1 0 Glycosyl transferases group 1 Porphobil_deam PF01379.15 KLO11299.1 - 2.3e-75 252.2 0.0 3.1e-75 251.8 0.0 1.1 1 0 0 1 1 1 1 Porphobilinogen deaminase, dipyromethane cofactor binding domain Porphobil_deamC PF03900.10 KLO11299.1 - 4.9e-17 61.8 0.2 1.1e-16 60.6 0.1 1.6 1 0 0 1 1 1 1 Porphobilinogen deaminase, C-terminal domain Ribosomal_L18p PF00861.17 KLO11299.1 - 0.0084 16.3 0.4 2.3 8.4 0.1 2.4 2 0 0 2 2 2 2 Ribosomal L18p/L5e family UQ_con PF00179.21 KLO11300.1 - 8.3e-27 93.3 0.0 9.7e-27 93.1 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 KLO11300.1 - 8e-05 22.3 0.0 9.4e-05 22.1 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 KLO11300.1 - 0.0038 17.1 0.0 0.0055 16.5 0.0 1.4 1 1 0 1 1 1 1 RWD domain UEV PF05743.8 KLO11300.1 - 0.12 12.0 0.0 0.17 11.5 0.0 1.1 1 0 0 1 1 1 0 UEV domain Copper-fist PF00649.13 KLO11301.1 - 8.1e-21 72.9 0.9 8.1e-21 72.9 0.6 3.7 4 0 0 4 4 4 1 Copper fist DNA binding domain Fe-S_biosyn PF01521.15 KLO11303.1 - 2.1e-21 75.9 0.0 2.7e-21 75.6 0.0 1.1 1 0 0 1 1 1 1 Iron-sulphur cluster biosynthesis DUF605 PF04652.11 KLO11303.1 - 2.5 7.3 12.5 3.1 7.0 8.7 1.1 1 0 0 1 1 1 0 Vta1 like UPF0052 PF01933.13 KLO11305.1 - 4.9e-37 127.8 0.0 7.1e-37 127.3 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised protein family UPF0052 SPRY PF00622.23 KLO11306.1 - 2.8e-15 56.4 0.2 3.9e-15 56.0 0.1 1.2 1 0 0 1 1 1 1 SPRY domain Homeobox PF00046.24 KLO11308.1 - 7.8e-43 143.9 8.4 9e-14 50.8 0.3 3.3 3 0 0 3 3 3 3 Homeobox domain Homeobox_KN PF05920.6 KLO11308.1 - 2.9e-12 46.0 0.3 0.0013 18.3 0.0 3.5 3 0 0 3 3 3 3 Homeobox KN domain HTH_3 PF01381.17 KLO11308.1 - 0.00077 19.2 0.1 1.2 9.0 0.0 2.8 2 0 0 2 2 2 2 Helix-turn-helix LTXXQ PF07813.7 KLO11308.1 - 0.25 11.7 2.7 2.9 8.4 0.2 3.1 3 0 0 3 3 3 0 LTXXQ motif family protein HTH_31 PF13560.1 KLO11308.1 - 0.61 10.3 3.6 10 6.3 0.2 3.8 2 1 1 3 3 3 0 Helix-turn-helix domain DUF4598 PF15370.1 KLO11309.1 - 1.1e-12 48.2 4.9 1.1e-12 48.2 3.4 1.9 2 1 0 2 2 2 1 Domain of unknown function (DUF4598) PP1_inhibitor PF05361.7 KLO11309.1 - 0.054 13.1 1.8 0.11 12.2 0.3 2.2 2 0 0 2 2 2 0 PKC-activated protein phosphatase-1 inhibitor Macoilin PF09726.4 KLO11309.1 - 0.2 9.9 4.9 0.23 9.6 3.4 1.1 1 0 0 1 1 1 0 Transmembrane protein SSP160 PF06933.6 KLO11309.1 - 0.48 8.3 16.1 0.67 7.8 11.2 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Tmemb_cc2 PF10267.4 KLO11309.1 - 0.83 8.1 4.2 1 7.8 2.9 1.1 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein AF-4 PF05110.8 KLO11309.1 - 5.8 4.6 16.7 10 3.8 11.6 1.4 1 0 0 1 1 1 0 AF-4 proto-oncoprotein Fumble PF03630.9 KLO11311.1 - 5.7e-118 393.6 0.1 1.2e-90 303.8 0.0 3.0 3 0 0 3 3 3 3 Fumble Adaptin_N PF01602.15 KLO11312.1 - 5.1e-114 381.4 0.3 1.8e-113 379.6 0.1 1.8 2 0 0 2 2 2 1 Adaptin N terminal region COP-gamma_platf PF08752.5 KLO11312.1 - 2.1e-58 196.3 1.4 4.8e-58 195.2 1.0 1.6 1 0 0 1 1 1 1 Coatomer gamma subunit appendage platform subdomain HEAT_2 PF13646.1 KLO11312.1 - 6.9e-15 55.1 1.1 0.00089 19.4 0.0 6.5 2 2 4 6 6 6 3 HEAT repeats HEAT PF02985.17 KLO11312.1 - 5.9e-06 25.9 6.9 0.3 11.2 0.1 6.2 7 0 0 7 7 7 2 HEAT repeat Cnd1 PF12717.2 KLO11312.1 - 0.00094 19.0 3.0 0.036 13.9 0.1 3.5 2 2 1 3 3 3 1 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.1 KLO11312.1 - 0.0049 17.3 3.2 0.35 11.4 0.0 4.3 3 1 2 5 5 5 1 HEAT-like repeat HEAT_PBS PF03130.11 KLO11312.1 - 0.026 14.9 0.1 76 4.2 0.0 4.9 5 0 0 5 5 5 0 PBS lyase HEAT-like repeat Pkinase PF00069.20 KLO11313.1 - 3.8e-38 131.1 0.0 4.6e-38 130.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KLO11313.1 - 1.2e-13 50.7 0.0 1.5e-13 50.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 KLO11313.1 - 0.00013 21.7 0.1 0.0024 17.6 0.0 2.5 2 1 0 3 3 3 1 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.6 KLO11313.1 - 0.019 13.7 0.1 0.027 13.2 0.1 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Pyr_redox_2 PF07992.9 KLO11314.1 - 3.4e-16 59.7 0.6 2.4e-15 56.9 0.4 3.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 KLO11314.1 - 2.3e-10 40.7 0.1 1.4e-07 31.8 0.0 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 KLO11314.1 - 1.4e-06 28.5 0.4 0.015 15.3 0.0 3.7 3 1 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 KLO11314.1 - 3e-06 26.4 0.8 0.0088 15.0 0.0 3.8 3 1 1 4 4 4 1 Lycopene cyclase protein K_oxygenase PF13434.1 KLO11314.1 - 6.6e-06 25.2 0.0 0.082 11.8 0.0 2.3 2 0 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.19 KLO11314.1 - 6.5e-05 21.9 6.7 0.054 12.3 0.0 3.9 3 1 1 4 4 4 2 FAD dependent oxidoreductase SIS PF01380.17 KLO11314.1 - 0.00045 19.8 0.2 0.007 15.9 0.0 2.7 3 0 0 3 3 3 1 SIS domain NAD_binding_9 PF13454.1 KLO11314.1 - 0.0015 18.3 3.7 4.8 6.9 0.0 4.1 3 1 0 4 4 4 1 FAD-NAD(P)-binding TrkA_N PF02254.13 KLO11314.1 - 0.0022 17.9 0.0 0.15 12.0 0.0 2.6 2 0 0 2 2 2 1 TrkA-N domain Thi4 PF01946.12 KLO11314.1 - 0.018 14.1 0.1 0.6 9.1 0.0 2.3 2 0 0 2 2 2 0 Thi4 family ThiF PF00899.16 KLO11314.1 - 0.027 14.3 0.0 5.4 6.8 0.0 2.6 3 0 0 3 3 3 0 ThiF family FAD_binding_3 PF01494.14 KLO11314.1 - 0.054 12.5 0.9 0.65 8.9 0.0 2.4 3 0 0 3 3 3 0 FAD binding domain Trp_halogenase PF04820.9 KLO11314.1 - 0.059 11.9 0.8 4 5.9 0.0 3.1 4 0 0 4 4 4 0 Tryptophan halogenase Runt PF00853.14 KLO11314.1 - 0.093 12.1 0.0 0.21 11.0 0.0 1.5 1 0 0 1 1 1 0 Runt domain DUF4147 PF13660.1 KLO11314.1 - 0.15 11.1 0.3 4.4 6.3 0.0 2.9 2 2 1 3 3 3 0 Domain of unknown function (DUF4147) Homeobox PF00046.24 KLO11315.1 - 1.5e-13 50.0 2.3 2.9e-13 49.2 1.6 1.4 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 KLO11315.1 - 0.019 14.6 0.1 0.051 13.2 0.1 1.6 1 0 0 1 1 1 0 Homeobox KN domain WD40 PF00400.27 KLO11316.1 - 1.3e-24 85.1 11.0 5.6e-05 22.8 0.1 7.2 8 0 0 8 8 8 5 WD domain, G-beta repeat Ribosomal_60s PF00428.14 KLO11316.1 - 3.1 8.2 10.5 9.1 6.7 7.3 1.8 1 0 0 1 1 1 0 60s Acidic ribosomal protein F-box-like PF12937.2 KLO11317.1 - 4.6e-09 35.8 0.0 1.4e-08 34.3 0.0 1.9 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KLO11317.1 - 0.0019 17.8 0.8 0.012 15.2 0.6 2.3 1 1 0 1 1 1 1 F-box domain PB1 PF00564.19 KLO11319.1 - 1.3e-08 34.3 0.0 2.5e-08 33.4 0.0 1.4 1 0 0 1 1 1 1 PB1 domain Abhydrolase_4 PF08386.5 KLO11320.1 - 0.092 12.6 0.0 1.6 8.6 0.0 2.0 2 0 0 2 2 2 0 TAP-like protein Chitin_synth_1 PF01644.12 KLO11323.1 - 1.3e-76 255.9 0.5 1.9e-76 255.3 0.4 1.3 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_2 PF03142.10 KLO11323.1 - 5.2e-26 91.1 1.0 2.6e-21 75.6 0.0 2.2 2 0 0 2 2 2 2 Chitin synthase Chitin_synth_1N PF08407.6 KLO11323.1 - 3.6e-25 87.4 0.0 8.2e-25 86.3 0.0 1.6 1 0 0 1 1 1 1 Chitin synthase N-terminal Glyco_trans_2_3 PF13632.1 KLO11323.1 - 7.8e-08 32.2 0.9 7.8e-08 32.2 0.6 2.6 2 1 1 3 3 3 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 KLO11323.1 - 8.5e-08 32.2 0.0 3e-07 30.4 0.0 1.8 2 0 0 2 2 2 1 Glycosyltransferase like family 2 cNMP_binding PF00027.24 KLO11324.1 - 4.5e-38 128.9 0.0 1.9e-16 59.6 0.0 4.5 4 0 0 4 4 4 4 Cyclic nucleotide-binding domain Patatin PF01734.17 KLO11324.1 - 2.7e-18 66.6 4.9 1.6e-12 47.7 1.4 2.8 3 0 0 3 3 3 2 Patatin-like phospholipase F-box-like PF12937.2 KLO11326.1 - 0.00031 20.3 3.1 0.00031 20.3 2.2 2.2 3 0 0 3 3 3 1 F-box-like F-box PF00646.28 KLO11326.1 - 0.00049 19.6 2.1 0.0013 18.3 1.5 1.8 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 KLO11327.1 - 0.00033 20.2 0.1 0.0016 18.1 0.1 2.3 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KLO11327.1 - 0.0063 16.1 0.3 0.0063 16.1 0.2 2.2 2 0 0 2 2 2 1 F-box domain Sec1 PF00995.18 KLO11328.1 - 1.2e-115 387.3 0.0 1.4e-115 387.1 0.0 1.0 1 0 0 1 1 1 1 Sec1 family Peripla_BP_4 PF13407.1 KLO11328.1 - 0.005 16.2 0.3 0.66 9.2 0.0 2.3 2 0 0 2 2 2 2 Periplasmic binding protein domain YABBY PF04690.8 KLO11329.1 - 1.6e-10 41.5 0.3 1.9e-10 41.2 0.2 1.1 1 0 0 1 1 1 1 YABBY protein HMG_box PF00505.14 KLO11329.1 - 0.00051 20.2 1.9 0.0007 19.8 1.3 1.3 1 0 0 1 1 1 1 HMG (high mobility group) box DUF1014 PF06244.7 KLO11329.1 - 0.00057 20.0 1.8 0.00075 19.7 1.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1014) HMG_box_2 PF09011.5 KLO11329.1 - 0.0015 18.8 2.4 0.0027 18.0 1.7 1.4 1 0 0 1 1 1 1 HMG-box domain F-box-like PF12937.2 KLO11330.1 - 8.3e-06 25.4 0.0 2.8e-05 23.7 0.0 2.0 1 1 0 1 1 1 1 F-box-like LRR_6 PF13516.1 KLO11330.1 - 7.9e-05 22.3 11.4 0.29 11.3 0.1 6.4 8 0 0 8 8 8 2 Leucine Rich repeat F-box PF00646.28 KLO11330.1 - 0.0073 15.9 0.1 0.033 13.8 0.0 2.1 2 0 0 2 2 2 1 F-box domain LRR_8 PF13855.1 KLO11330.1 - 0.26 11.0 8.1 7.9 6.3 0.1 4.7 6 0 0 6 6 6 0 Leucine rich repeat LRR_1 PF00560.28 KLO11330.1 - 0.84 9.9 9.1 14 6.1 0.1 5.8 6 0 0 6 6 6 0 Leucine Rich Repeat Methyltransf_16 PF10294.4 KLO11331.1 - 4.1e-14 52.4 0.0 7e-14 51.6 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase MTS PF05175.9 KLO11331.1 - 0.0078 15.6 0.0 0.048 13.0 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_18 PF12847.2 KLO11331.1 - 0.071 13.6 0.1 0.2 12.2 0.1 1.7 1 1 0 1 1 1 0 Methyltransferase domain KCNQC3-Ank-G_bd PF11956.3 KLO11331.1 - 0.12 12.4 0.1 0.39 10.7 0.0 1.8 2 0 0 2 2 2 0 Ankyrin-G binding motif of KCNQ2-3 MFS_1 PF07690.11 KLO11332.1 - 6.3e-19 67.8 17.8 7e-18 64.4 12.4 1.9 2 0 0 2 2 2 2 Major Facilitator Superfamily Cpn60_TCP1 PF00118.19 KLO11333.1 - 6.5e-140 466.9 0.0 7.5e-140 466.7 0.0 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family SF3b10 PF07189.6 KLO11334.1 - 7.3e-31 105.8 0.0 9.1e-31 105.5 0.0 1.0 1 0 0 1 1 1 1 Splicing factor 3B subunit 10 (SF3b10) Methyltransf_11 PF08241.7 KLO11335.1 - 5.9e-14 52.3 0.0 1.2e-13 51.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KLO11335.1 - 2.7e-10 40.2 0.0 7.1e-10 38.8 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KLO11335.1 - 1.4e-08 35.2 0.0 3.9e-08 33.8 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KLO11335.1 - 6.6e-08 32.9 0.0 2e-07 31.4 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KLO11335.1 - 2.5e-07 30.3 0.0 4.7e-07 29.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KLO11335.1 - 3e-07 29.8 0.0 5e-07 29.0 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.1 KLO11335.1 - 1.7e-06 28.3 0.0 4.3e-06 27.0 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KLO11335.1 - 0.0012 18.8 0.0 0.0027 17.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_29 PF03141.11 KLO11335.1 - 0.0028 16.0 0.0 0.0048 15.2 0.0 1.3 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_2 PF00891.13 KLO11335.1 - 0.011 14.9 0.0 0.024 13.8 0.0 1.5 2 0 0 2 2 2 0 O-methyltransferase FtsJ PF01728.14 KLO11335.1 - 0.021 14.7 0.0 0.044 13.7 0.0 1.4 1 0 0 1 1 1 0 FtsJ-like methyltransferase MetW PF07021.7 KLO11335.1 - 0.026 13.9 0.0 0.052 12.9 0.0 1.4 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW CMAS PF02353.15 KLO11335.1 - 0.22 10.5 0.0 0.35 9.8 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Sas10_Utp3 PF04000.10 KLO11336.1 - 4.7e-19 68.3 0.1 1e-18 67.2 0.1 1.6 1 0 0 1 1 1 1 Sas10/Utp3/C1D family PA28_alpha PF02251.13 KLO11336.1 - 0.033 14.3 0.3 0.069 13.3 0.2 1.5 1 0 0 1 1 1 0 Proteasome activator pa28 alpha subunit DUF3176 PF11374.3 KLO11337.1 - 0.0084 15.9 0.5 0.018 14.8 0.3 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3176) SNF2_N PF00176.18 KLO11338.1 - 7.6e-63 212.0 0.0 1.2e-62 211.4 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain HIRAN PF08797.6 KLO11338.1 - 1.3e-17 63.6 0.0 4e-17 62.0 0.0 1.9 1 0 0 1 1 1 1 HIRAN domain Helicase_C PF00271.26 KLO11338.1 - 3e-13 49.4 0.0 1.2e-12 47.5 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.24 KLO11338.1 - 1.5e-06 27.8 0.0 2.8e-06 26.9 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase zf-RING_2 PF13639.1 KLO11338.1 - 4.7e-06 26.3 7.4 4.7e-06 26.3 5.1 1.9 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4 PF00097.20 KLO11338.1 - 4.9e-06 26.0 8.9 9.6e-06 25.1 6.2 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KLO11338.1 - 4.5e-05 23.0 7.2 8.7e-05 22.1 5.0 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 KLO11338.1 - 7.3e-05 22.7 9.3 7.3e-05 22.7 6.4 1.8 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KLO11338.1 - 0.00013 21.5 4.8 0.00025 20.6 3.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 KLO11338.1 - 0.0012 18.6 1.2 0.0029 17.4 0.8 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_4 PF15227.1 KLO11338.1 - 0.0022 17.8 10.4 0.0045 16.8 7.2 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-MIZ PF02891.15 KLO11338.1 - 0.0028 17.1 4.2 0.0053 16.2 2.9 1.4 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger zf-Nse PF11789.3 KLO11338.1 - 0.019 14.4 5.0 0.044 13.3 3.5 1.6 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit Patched PF02460.13 KLO11338.1 - 0.11 10.4 0.0 0.18 9.6 0.0 1.3 1 0 0 1 1 1 0 Patched family zf-RING_4 PF14570.1 KLO11338.1 - 0.99 9.0 7.2 2.2 7.9 5.0 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Esterase_phd PF10503.4 KLO11339.1 - 6.4e-27 94.2 0.1 9.1e-27 93.7 0.1 1.2 1 0 0 1 1 1 1 Esterase PHB depolymerase CBM_1 PF00734.13 KLO11339.1 - 1.2e-12 47.2 10.7 4.1e-12 45.5 7.4 2.0 1 0 0 1 1 1 1 Fungal cellulose binding domain Peptidase_S9 PF00326.16 KLO11339.1 - 4e-11 42.5 1.0 5.4e-11 42.1 0.7 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 KLO11339.1 - 6.5e-05 22.7 0.1 0.00011 22.0 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KLO11339.1 - 0.0016 18.3 0.1 0.003 17.4 0.1 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family COesterase PF00135.23 KLO11339.1 - 0.0024 16.6 0.4 0.0024 16.6 0.3 1.8 3 0 0 3 3 3 1 Carboxylesterase family Esterase PF00756.15 KLO11339.1 - 0.011 15.1 0.2 0.017 14.5 0.2 1.4 1 0 0 1 1 1 0 Putative esterase Abhydrolase_1 PF00561.15 KLO11339.1 - 0.044 13.3 0.1 0.073 12.6 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_3 PF07859.8 KLO11339.1 - 0.057 12.9 0.1 0.1 12.1 0.0 1.5 1 0 0 1 1 1 0 alpha/beta hydrolase fold Esterase_phd PF10503.4 KLO11340.1 - 4.7e-26 91.4 0.2 6.7e-26 90.8 0.1 1.1 1 0 0 1 1 1 1 Esterase PHB depolymerase CBM_1 PF00734.13 KLO11340.1 - 3.9e-12 45.6 9.4 3.9e-12 45.6 6.5 2.3 2 0 0 2 2 2 1 Fungal cellulose binding domain Peptidase_S9 PF00326.16 KLO11340.1 - 5.9e-12 45.2 1.5 8.2e-12 44.7 1.0 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 KLO11340.1 - 2.8e-05 23.8 0.2 4.5e-05 23.2 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KLO11340.1 - 0.0075 16.1 0.1 0.012 15.4 0.1 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family COesterase PF00135.23 KLO11340.1 - 0.0082 14.8 1.5 0.0082 14.8 1.0 1.8 3 0 0 3 3 3 1 Carboxylesterase family Esterase PF00756.15 KLO11340.1 - 0.0096 15.3 0.2 0.013 14.9 0.2 1.4 1 0 0 1 1 1 1 Putative esterase Abhydrolase_2 PF02230.11 KLO11340.1 - 0.15 11.5 0.5 0.25 10.7 0.1 1.6 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Zn_clus PF00172.13 KLO11341.1 - 2.9e-08 33.4 5.6 4.4e-08 32.9 3.9 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain APC_CDC26 PF10471.4 KLO11341.1 - 0.33 11.7 11.2 0.21 12.3 2.2 2.3 2 0 0 2 2 2 0 Anaphase-promoting complex APC subunit 1 Cytochrom_C PF00034.16 KLO11341.1 - 2.5 8.9 8.9 1.7 9.4 3.0 2.7 1 1 0 2 2 2 0 Cytochrome c BSP PF04450.7 KLO11342.1 - 5.1e-66 222.0 0.0 6.4e-66 221.7 0.0 1.1 1 0 0 1 1 1 1 Peptidase of plants and bacteria Peptidase_MA_2 PF13485.1 KLO11342.1 - 2.8e-06 27.4 0.0 5.3e-06 26.5 0.0 1.5 1 1 0 1 1 1 1 Peptidase MA superfamily SprT-like PF10263.4 KLO11342.1 - 6e-05 22.7 0.1 9.4e-05 22.1 0.1 1.3 1 0 0 1 1 1 1 SprT-like family NIF PF03031.13 KLO11343.1 - 8.5e-24 84.0 0.0 8.4e-21 74.2 0.0 2.4 2 0 0 2 2 2 2 NLI interacting factor-like phosphatase PTCB-BRCT PF12738.2 KLO11343.1 - 1.4e-11 44.0 0.2 3.4e-11 42.8 0.1 1.7 1 0 0 1 1 1 1 twin BRCT domain BRCT PF00533.21 KLO11343.1 - 3.1e-06 27.2 0.0 8.9e-06 25.7 0.0 1.8 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain adh_short_C2 PF13561.1 KLO11344.1 - 2.3e-22 79.9 0.1 2.6e-22 79.7 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 KLO11344.1 - 4.8e-06 26.5 1.2 6.7e-06 26.1 0.8 1.2 1 0 0 1 1 1 1 short chain dehydrogenase NAD_binding_10 PF13460.1 KLO11344.1 - 0.0019 18.2 0.9 0.013 15.5 0.6 2.1 1 1 0 1 1 1 1 NADH(P)-binding THF_DHG_CYH_C PF02882.14 KLO11344.1 - 0.0026 16.8 0.6 0.004 16.2 0.4 1.3 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Eno-Rase_NADH_b PF12242.3 KLO11344.1 - 0.04 13.6 1.0 0.1 12.3 0.7 1.8 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase adh_short_C2 PF13561.1 KLO11345.1 - 1.7e-20 73.8 0.0 2e-20 73.5 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 KLO11345.1 - 0.00032 20.6 0.6 0.0018 18.1 0.4 2.1 1 1 0 1 1 1 1 short chain dehydrogenase NAD_binding_10 PF13460.1 KLO11345.1 - 0.014 15.4 0.4 0.03 14.3 0.3 1.6 1 0 0 1 1 1 0 NADH(P)-binding Eno-Rase_NADH_b PF12242.3 KLO11345.1 - 0.14 11.9 0.8 0.39 10.5 0.6 1.8 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase NIF3 PF01784.13 KLO11346.1 - 5.6e-60 202.9 0.0 6.9e-60 202.6 0.0 1.0 1 0 0 1 1 1 1 NIF3 (NGG1p interacting factor 3) RhoGAP PF00620.22 KLO11347.1 - 6.5e-21 74.5 0.0 1.7e-11 43.9 0.0 3.0 3 0 0 3 3 3 2 RhoGAP domain Myosin_tail_1 PF01576.14 KLO11347.1 - 0.29 8.7 0.1 0.48 8.0 0.1 1.3 1 0 0 1 1 1 0 Myosin tail F-box-like PF12937.2 KLO11348.1 - 2.4e-10 39.9 4.2 1.6e-09 37.3 0.3 2.6 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 KLO11348.1 - 0.0014 18.2 0.4 0.0014 18.2 0.3 2.3 2 0 0 2 2 2 1 F-box domain DUF4200 PF13863.1 KLO11348.1 - 0.059 13.3 0.6 0.12 12.3 0.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) DUF3005 PF11448.3 KLO11348.1 - 0.08 12.5 0.0 0.14 11.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3005) HN PF00423.14 KLO11348.1 - 0.19 9.9 0.1 0.28 9.4 0.1 1.1 1 0 0 1 1 1 0 Haemagglutinin-neuraminidase His_Phos_1 PF00300.17 KLO11349.1 - 2.2e-18 66.8 0.0 3.3e-18 66.2 0.0 1.3 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Spt5-NGN PF03439.8 KLO11350.1 - 4.4e-13 48.7 0.0 8.3e-13 47.8 0.0 1.5 1 0 0 1 1 1 1 Early transcription elongation factor of RNA pol II, NGN section KOW PF00467.24 KLO11350.1 - 1.3e-06 27.8 31.2 0.026 14.2 0.5 6.2 6 0 0 6 6 6 4 KOW motif HAS-barrel PF09378.5 KLO11350.1 - 0.44 10.4 5.6 15 5.5 0.2 3.6 3 1 1 4 4 4 0 HAS barrel domain F-box-like PF12937.2 KLO11351.1 - 4.4e-07 29.5 0.1 1.8e-06 27.5 0.1 2.1 1 0 0 1 1 1 1 F-box-like F-box-like_2 PF13013.1 KLO11351.1 - 0.042 13.5 0.1 0.13 12.0 0.0 1.8 1 1 0 1 1 1 0 F-box-like domain p450 PF00067.17 KLO11354.1 - 9.3e-57 192.5 0.0 2e-56 191.4 0.0 1.5 1 1 0 1 1 1 1 Cytochrome P450 F-box-like PF12937.2 KLO11355.1 - 9.1e-08 31.7 0.1 4.4e-07 29.5 0.1 2.2 1 0 0 1 1 1 1 F-box-like F-box-like PF12937.2 KLO11357.1 - 2.1e-07 30.5 0.3 6e-07 29.0 0.2 1.9 1 0 0 1 1 1 1 F-box-like F-box-like_2 PF13013.1 KLO11357.1 - 0.03 14.0 0.2 0.065 12.9 0.1 1.5 1 0 0 1 1 1 0 F-box-like domain F-box PF00646.28 KLO11357.1 - 0.12 12.0 0.8 1.2 8.8 0.6 2.5 1 1 0 1 1 1 0 F-box domain HWE_HK PF07536.9 KLO11359.1 - 0.12 12.8 0.7 0.24 11.8 0.4 1.6 1 1 0 1 1 1 0 HWE histidine kinase F-box-like PF12937.2 KLO11360.1 - 1.7e-06 27.6 1.8 2.1e-06 27.3 0.1 2.1 2 0 0 2 2 2 1 F-box-like F-box-like_2 PF13013.1 KLO11360.1 - 7.1e-05 22.4 0.3 0.00017 21.2 0.1 1.8 1 1 0 1 1 1 1 F-box-like domain F-box PF00646.28 KLO11360.1 - 0.017 14.7 1.5 1.8 8.2 0.8 3.8 2 1 0 2 2 2 0 F-box domain p450 PF00067.17 KLO11363.1 - 3.5e-58 197.2 0.0 5.5e-58 196.6 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 KOW PF00467.24 KLO11364.1 - 7.7e-12 44.4 25.9 5.6e-05 22.7 0.2 5.3 5 0 0 5 5 5 4 KOW motif Spt5-NGN PF03439.8 KLO11364.1 - 2.5e-11 43.1 0.0 5.4e-11 42.0 0.0 1.6 1 0 0 1 1 1 1 Early transcription elongation factor of RNA pol II, NGN section DUF3530 PF12048.3 KLO11364.1 - 0.12 11.3 0.0 0.21 10.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3530) Ribosomal_L9_N PF01281.14 KLO11364.1 - 9.1 5.6 8.2 7.6 5.8 0.1 3.8 3 1 1 4 4 4 0 Ribosomal protein L9, N-terminal domain F-box-like PF12937.2 KLO11367.1 - 0.017 14.8 0.2 0.094 12.4 0.0 2.4 3 0 0 3 3 3 0 F-box-like F-box-like PF12937.2 KLO11370.1 - 1.5e-09 37.4 0.3 4.2e-09 35.9 0.2 1.9 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KLO11370.1 - 0.017 14.7 7.8 0.25 11.0 5.4 2.5 1 1 0 1 1 1 0 F-box domain Epimerase PF01370.16 KLO11371.1 - 2.9e-21 75.9 0.0 4.5e-21 75.3 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 KLO11371.1 - 3.5e-14 52.1 0.0 8.2e-14 50.9 0.0 1.6 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 KLO11371.1 - 5.6e-13 49.3 1.8 1.6e-12 47.7 1.3 1.8 1 1 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 KLO11371.1 - 9.3e-10 37.8 0.2 5.4e-09 35.3 0.1 1.9 1 1 0 1 1 1 1 Male sterility protein NmrA PF05368.8 KLO11371.1 - 2.8e-05 23.5 0.1 4.4e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family adh_short PF00106.20 KLO11371.1 - 6e-05 23.0 0.3 0.00012 22.0 0.2 1.5 1 0 0 1 1 1 1 short chain dehydrogenase Polysacc_synt_2 PF02719.10 KLO11371.1 - 0.00052 19.0 0.1 0.00082 18.3 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein KR PF08659.5 KLO11371.1 - 0.0036 16.9 0.2 0.0072 16.0 0.1 1.5 1 1 0 1 1 1 1 KR domain Saccharop_dh PF03435.13 KLO11371.1 - 0.095 11.6 0.1 0.13 11.2 0.1 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase COesterase PF00135.23 KLO11372.1 - 2.2e-99 333.5 0.0 2.5e-99 333.4 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 KLO11372.1 - 3.4e-08 33.3 0.1 1.3e-07 31.4 0.1 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Metallophos PF00149.23 KLO11373.1 - 2e-08 33.8 0.1 9.8e-07 28.3 0.0 2.2 2 0 0 2 2 2 2 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 KLO11373.1 - 3.6e-06 26.8 0.0 1.1e-05 25.3 0.0 1.8 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain adh_short PF00106.20 KLO11374.1 - 2.2e-17 63.4 1.5 9.6e-17 61.4 1.0 2.0 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KLO11374.1 - 1.9e-08 34.3 0.0 2.8e-08 33.8 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KLO11374.1 - 2.3e-07 30.6 0.6 5.4e-07 29.4 0.4 1.8 1 1 0 1 1 1 1 KR domain Epimerase PF01370.16 KLO11374.1 - 9.3e-07 28.5 0.6 8.4e-06 25.3 0.4 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 KLO11374.1 - 9.7e-05 22.4 1.5 0.0011 19.0 0.9 2.3 1 1 1 2 2 2 1 NADH(P)-binding NmrA PF05368.8 KLO11374.1 - 0.00017 20.9 0.6 0.00031 20.0 0.4 1.3 1 0 0 1 1 1 1 NmrA-like family NAD_binding_4 PF07993.7 KLO11374.1 - 0.00045 19.2 0.9 0.015 14.2 0.1 2.6 2 2 0 2 2 2 1 Male sterility protein 3Beta_HSD PF01073.14 KLO11374.1 - 0.24 10.0 3.8 0.046 12.4 0.3 1.5 2 0 0 2 2 2 0 3-beta hydroxysteroid dehydrogenase/isomerase family XFP_N PF09364.5 KLO11375.1 - 2.6e-154 513.3 0.0 3.3e-154 513.0 0.0 1.1 1 0 0 1 1 1 1 XFP N-terminal domain XFP_C PF09363.5 KLO11375.1 - 2.9e-71 239.0 0.0 7.3e-71 237.8 0.0 1.6 2 0 0 2 2 2 1 XFP C-terminal domain XFP PF03894.10 KLO11375.1 - 1.9e-69 232.8 0.0 3e-69 232.1 0.0 1.3 1 0 0 1 1 1 1 D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase TPP_enzyme_C PF02775.16 KLO11375.1 - 0.00085 18.9 0.2 0.0031 17.1 0.1 1.9 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Transketolase_C PF02780.15 KLO11375.1 - 0.12 12.2 0.1 0.26 11.2 0.1 1.5 1 0 0 1 1 1 0 Transketolase, C-terminal domain F-box-like PF12937.2 KLO11376.1 - 0.011 15.4 1.7 0.011 15.4 1.2 2.2 2 0 0 2 2 2 0 F-box-like Gp_UL130 PF11668.3 KLO11377.1 - 0.11 12.0 0.0 0.25 10.8 0.0 1.6 2 0 0 2 2 2 0 HCMV glycoprotein pUL130 zf-MYND PF01753.13 KLO11378.1 - 4.6e-12 45.6 22.2 2.8e-10 39.8 5.4 2.9 3 0 0 3 3 3 2 MYND finger zf-Mss51 PF13824.1 KLO11378.1 - 1.6 8.6 10.9 3 7.7 1.6 2.8 2 0 0 2 2 2 0 Zinc-finger of mitochondrial splicing suppressor 51 Ecl1 PF12855.2 KLO11378.1 - 2.6 7.4 7.4 9.3 5.6 5.1 1.9 1 0 0 1 1 1 0 Life-span regulatory factor zf-MYND PF01753.13 KLO11379.1 - 8.9e-12 44.6 24.6 5.5e-10 38.9 7.2 2.6 2 0 0 2 2 2 2 MYND finger zf-Mss51 PF13824.1 KLO11379.1 - 0.94 9.3 18.0 0.63 9.9 3.3 2.9 3 0 0 3 3 3 0 Zinc-finger of mitochondrial splicing suppressor 51 TPR_12 PF13424.1 KLO11380.1 - 3.4e-15 55.7 11.6 7.7e-05 22.5 0.1 6.1 1 1 7 8 8 8 7 Tetratricopeptide repeat DUF3856 PF12968.2 KLO11380.1 - 1.3e-08 34.7 0.7 0.0028 17.4 0.0 4.2 1 1 3 5 5 5 3 Domain of Unknown Function (DUF3856) AAA_16 PF13191.1 KLO11380.1 - 1e-07 32.1 0.0 5.5e-07 29.7 0.0 2.3 1 0 0 1 1 1 1 AAA ATPase domain Apc5 PF12862.2 KLO11380.1 - 2.1e-07 30.6 13.5 0.056 13.2 0.0 7.3 2 1 5 7 7 7 2 Anaphase-promoting complex subunit 5 TPR_10 PF13374.1 KLO11380.1 - 2e-05 24.3 0.0 17 5.4 0.0 6.3 6 0 0 6 6 6 0 Tetratricopeptide repeat NACHT PF05729.7 KLO11380.1 - 0.00032 20.3 0.3 0.0015 18.1 0.0 2.4 3 0 0 3 3 3 1 NACHT domain TPR_6 PF13174.1 KLO11380.1 - 0.00049 20.3 0.5 4.5 7.9 0.1 5.4 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_8 PF13181.1 KLO11380.1 - 0.0006 19.4 0.7 31 4.6 0.0 5.5 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_2 PF07719.12 KLO11380.1 - 0.004 16.9 2.1 22 5.2 0.2 5.7 5 0 0 5 5 5 0 Tetratricopeptide repeat AAA PF00004.24 KLO11380.1 - 0.013 15.7 0.0 0.051 13.7 0.0 2.1 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) TPR_7 PF13176.1 KLO11380.1 - 0.015 15.0 0.2 18 5.4 0.0 4.7 5 0 0 5 5 4 0 Tetratricopeptide repeat AAA_19 PF13245.1 KLO11380.1 - 0.028 14.1 0.0 0.084 12.6 0.0 1.7 1 0 0 1 1 1 0 Part of AAA domain AAA_22 PF13401.1 KLO11380.1 - 0.05 13.7 0.0 0.3 11.2 0.0 2.4 2 0 0 2 2 2 0 AAA domain ArgK PF03308.11 KLO11380.1 - 0.12 11.1 0.0 0.85 8.3 0.0 2.3 1 1 1 2 2 2 0 ArgK protein TPR_4 PF07721.9 KLO11380.1 - 0.14 12.6 0.8 3.3 8.4 0.1 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat AAA_17 PF13207.1 KLO11380.1 - 0.16 12.8 0.1 1.5 9.6 0.0 2.7 2 0 0 2 2 2 0 AAA domain TPR_12 PF13424.1 KLO11382.1 - 6.6e-20 70.8 22.6 5.3e-07 29.4 0.1 7.0 5 1 1 7 7 6 5 Tetratricopeptide repeat DUF3856 PF12968.2 KLO11382.1 - 5e-08 32.8 14.6 0.017 14.9 0.7 5.1 2 1 3 6 6 6 4 Domain of Unknown Function (DUF3856) AAA_16 PF13191.1 KLO11382.1 - 1.9e-07 31.2 2.0 9.4e-07 28.9 0.0 3.2 3 1 0 3 3 3 1 AAA ATPase domain NACHT PF05729.7 KLO11382.1 - 9.5e-06 25.3 0.0 3e-05 23.7 0.0 1.9 1 0 0 1 1 1 1 NACHT domain AAA_19 PF13245.1 KLO11382.1 - 2.8e-05 23.7 0.1 0.00011 21.8 0.0 2.1 2 0 0 2 2 1 1 Part of AAA domain TPR_10 PF13374.1 KLO11382.1 - 0.00045 20.0 17.7 2 8.4 0.0 8.8 11 0 0 11 11 10 2 Tetratricopeptide repeat DUF4615 PF15393.1 KLO11382.1 - 0.0014 18.8 8.4 14 5.9 0.0 5.9 5 0 0 5 5 5 0 Domain of unknown function (DUF4615) AAA PF00004.24 KLO11382.1 - 0.0019 18.4 0.1 0.022 14.9 0.0 2.7 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) NTPase_1 PF03266.10 KLO11382.1 - 0.0043 16.7 0.0 0.018 14.7 0.0 2.1 2 0 0 2 2 2 1 NTPase AAA_5 PF07728.9 KLO11382.1 - 0.0084 15.8 0.0 0.1 12.3 0.0 2.8 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 KLO11382.1 - 0.01 15.9 0.2 0.16 12.1 0.0 3.2 3 0 0 3 3 2 0 AAA domain Apc5 PF12862.2 KLO11382.1 - 0.013 15.3 27.7 6.9 6.5 0.1 8.8 4 2 5 9 9 8 0 Anaphase-promoting complex subunit 5 AAA_17 PF13207.1 KLO11382.1 - 0.017 15.9 1.3 0.11 13.3 0.0 3.2 2 2 0 2 2 2 0 AAA domain AAA_25 PF13481.1 KLO11382.1 - 0.034 13.5 0.0 0.092 12.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 KLO11382.1 - 0.04 14.2 0.1 0.39 11.0 0.0 2.9 2 0 0 2 2 1 0 AAA domain NPV_P10 PF05531.7 KLO11382.1 - 0.042 14.1 4.0 0.16 12.2 0.3 3.9 3 0 0 3 3 2 0 Nucleopolyhedrovirus P10 protein TPR_2 PF07719.12 KLO11382.1 - 0.058 13.3 14.6 4.8 7.3 0.0 7.4 9 0 0 9 9 7 0 Tetratricopeptide repeat DUF2075 PF09848.4 KLO11382.1 - 0.09 11.7 0.0 0.09 11.7 0.0 2.7 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2075) DASH_Dam1 PF08653.5 KLO11382.1 - 0.095 12.4 13.7 12 5.7 0.0 7.5 9 0 0 9 9 6 0 DASH complex subunit Dam1 Fumarate_red_C PF02300.12 KLO11382.1 - 0.11 12.3 0.2 1.6 8.5 0.1 2.4 2 0 0 2 2 2 0 Fumarate reductase subunit C ArgK PF03308.11 KLO11382.1 - 0.19 10.5 0.2 0.62 8.7 0.0 1.9 1 1 1 2 2 2 0 ArgK protein DUF1212 PF06738.7 KLO11382.1 - 0.23 10.8 1.3 2.7 7.4 0.2 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1212) BCNT PF07572.7 KLO11384.1 - 2.6e-16 59.3 0.1 2.6e-16 59.3 0.0 1.9 2 0 0 2 2 2 1 Bucentaur or craniofacial development FA_desaturase PF00487.19 KLO11385.1 - 1.8e-14 53.8 19.8 1.8e-14 53.8 13.7 1.6 1 1 1 2 2 2 1 Fatty acid desaturase Cyt-b5 PF00173.23 KLO11385.1 - 7.8e-13 48.0 0.0 1.6e-12 47.0 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain F-box-like PF12937.2 KLO11386.1 - 0.0012 18.5 0.0 0.0028 17.3 0.0 1.6 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.2 KLO11386.1 - 0.0055 16.3 0.2 0.31 10.7 0.0 3.3 3 1 1 4 4 4 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KLO11386.1 - 0.095 12.4 0.0 3.3 7.5 0.0 2.8 2 0 0 2 2 2 0 Leucine rich repeat Cul7 PF11515.3 KLO11386.1 - 0.14 12.1 0.0 0.28 11.1 0.0 1.4 1 0 0 1 1 1 0 Mouse development and cellular proliferation protein Cullin-7 HEAT PF02985.17 KLO11387.1 - 0.001 18.9 7.4 7.9 6.8 0.0 8.0 9 0 0 9 9 9 1 HEAT repeat Anticodon_1 PF08264.8 KLO11387.1 - 0.01 15.5 2.5 0.2 11.4 0.0 3.4 4 0 0 4 4 4 0 Anticodon-binding domain of tRNA Cnd1 PF12717.2 KLO11387.1 - 0.3 10.9 0.0 0.3 10.9 0.0 5.0 5 2 1 6 6 6 0 non-SMC mitotic condensation complex subunit 1 NARP1 PF12569.3 KLO11388.1 - 2.6e-152 508.2 1.4 1.5e-148 495.7 0.0 2.9 2 1 1 3 3 3 2 NMDA receptor-regulated protein 1 TPR_11 PF13414.1 KLO11388.1 - 2.7e-20 71.7 9.1 5.4e-05 22.7 0.6 7.0 5 1 1 6 6 6 4 TPR repeat TPR_2 PF07719.12 KLO11388.1 - 8.2e-15 53.4 10.7 0.0031 17.2 0.1 8.7 9 0 0 9 9 8 4 Tetratricopeptide repeat TPR_16 PF13432.1 KLO11388.1 - 3.1e-13 50.0 18.5 0.039 14.6 0.4 8.6 8 2 1 9 9 9 4 Tetratricopeptide repeat TPR_14 PF13428.1 KLO11388.1 - 3.5e-13 48.9 19.9 0.64 10.8 0.0 11.6 7 2 4 12 12 12 4 Tetratricopeptide repeat TPR_1 PF00515.23 KLO11388.1 - 3.5e-12 45.3 3.2 0.0022 17.5 0.3 6.2 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_17 PF13431.1 KLO11388.1 - 3.7e-11 42.3 0.2 0.23 11.7 0.0 7.3 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_19 PF14559.1 KLO11388.1 - 4.3e-11 42.9 20.6 0.017 15.4 0.0 9.0 8 2 3 11 11 10 3 Tetratricopeptide repeat TPR_12 PF13424.1 KLO11388.1 - 3.2e-09 36.5 10.7 0.012 15.4 0.0 6.1 3 1 3 7 7 6 3 Tetratricopeptide repeat TPR_9 PF13371.1 KLO11388.1 - 2e-07 30.7 3.2 0.32 10.8 0.1 5.3 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_4 PF07721.9 KLO11388.1 - 2.3e-06 27.4 7.9 0.99 10.0 0.3 6.1 6 0 0 6 6 5 2 Tetratricopeptide repeat Apc3 PF12895.2 KLO11388.1 - 5.2e-06 26.4 6.6 0.071 13.2 1.0 5.9 4 1 3 7 7 7 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.1 KLO11388.1 - 8.1e-06 25.9 12.0 1 9.9 0.1 6.8 7 0 0 7 7 5 1 Tetratricopeptide repeat TPR_8 PF13181.1 KLO11388.1 - 0.0021 17.7 9.7 0.26 11.1 0.0 5.3 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_7 PF13176.1 KLO11388.1 - 0.0038 16.9 15.4 2.5 8.1 0.1 6.8 7 0 0 7 7 6 2 Tetratricopeptide repeat DUF1510 PF07423.6 KLO11388.1 - 0.017 14.5 0.1 0.029 13.7 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Rapsyn_N PF10579.4 KLO11388.1 - 0.082 12.7 0.2 2.8 7.8 0.0 3.0 2 1 0 2 2 2 0 Rapsyn N-terminal myristoylation and linker region DUF3366 PF11846.3 KLO11388.1 - 0.16 11.7 3.6 0.22 11.4 0.1 2.7 3 0 0 3 3 2 0 Domain of unknown function (DUF3366) BTAD PF03704.12 KLO11388.1 - 1.1 9.5 8.3 0.11 12.8 1.3 2.7 3 0 0 3 3 3 0 Bacterial transcriptional activator domain Acetyltransf_7 PF13508.1 KLO11389.1 - 8.4e-10 38.6 0.0 1.4e-09 37.9 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 KLO11389.1 - 3.1e-07 30.3 0.0 5.6e-07 29.5 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 KLO11389.1 - 1.2e-05 25.3 0.0 2.6e-05 24.2 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 KLO11389.1 - 3.5e-05 23.4 0.0 0.00029 20.5 0.0 2.1 2 0 0 2 2 2 1 FR47-like protein Acetyltransf_8 PF13523.1 KLO11389.1 - 0.0055 16.5 0.0 0.0081 16.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 KLO11389.1 - 0.043 13.6 0.0 0.079 12.8 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Vert_IL3-reg_TF PF06529.6 KLO11389.1 - 0.13 11.2 0.0 0.17 10.7 0.0 1.2 1 0 0 1 1 1 0 Vertebrate interleukin-3 regulated transcription factor Pkinase PF00069.20 KLO11390.1 - 9.7e-43 146.1 0.0 5.1e-28 97.9 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 KLO11390.1 - 4.9e-24 84.7 0.0 9.8e-24 83.8 0.0 1.4 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.18 KLO11390.1 - 0.028 14.1 3.8 0.025 14.3 1.1 2.0 2 1 0 2 2 2 0 Phosphotransferase enzyme family LtrA PF06772.6 KLO11394.1 - 1e-07 31.2 17.0 0.0004 19.3 3.8 2.4 2 0 0 2 2 2 2 Bacterial low temperature requirement A protein (LtrA) ORC3_N PF07034.6 KLO11395.1 - 0.069 12.1 1.6 3.7 6.4 0.2 2.3 2 0 0 2 2 2 0 Origin recognition complex (ORC) subunit 3 N-terminus Actin PF00022.14 KLO11395.1 - 0.12 10.7 0.0 0.15 10.4 0.0 1.2 1 0 0 1 1 1 0 Actin Transp_cyt_pur PF02133.10 KLO11397.1 - 8.3e-40 136.6 28.4 1.8e-38 132.2 19.7 2.0 1 1 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin DUF4407 PF14362.1 KLO11397.1 - 4.2 6.2 5.4 7.3 5.4 3.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) UbiA PF01040.13 KLO11398.1 - 2.4e-15 56.4 10.0 3.2e-15 56.0 7.0 1.2 1 0 0 1 1 1 1 UbiA prenyltransferase family UbiA PF01040.13 KLO11399.1 - 1.1e-17 64.1 11.6 1.4e-17 63.7 8.1 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family DUF4177 PF13783.1 KLO11400.1 - 0.0011 18.5 0.0 0.0025 17.4 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4177) MdcG PF10620.4 KLO11400.1 - 0.15 11.6 0.0 0.23 10.9 0.0 1.2 1 0 0 1 1 1 0 Phosphoribosyl-dephospho-CoA transferase MdcG DUF4177 PF13783.1 KLO11401.1 - 0.0058 16.2 0.0 0.019 14.6 0.0 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF4177) DUF4177 PF13783.1 KLO11402.1 - 0.0061 16.1 0.0 0.014 15.0 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4177) RRM_1 PF00076.17 KLO11403.1 - 1.9e-18 65.8 0.0 8.5e-09 34.9 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KLO11403.1 - 2.8e-17 62.4 0.0 9.1e-08 31.9 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KLO11403.1 - 1.2e-09 37.8 0.0 0.00015 21.5 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DHC_N2 PF08393.8 KLO11404.1 - 0.12 10.8 5.6 0.16 10.4 1.5 2.1 1 1 1 2 2 2 0 Dynein heavy chain, N-terminal region 2 PIN_2 PF10130.4 KLO11404.1 - 0.32 11.0 2.1 2.6 8.0 0.0 2.2 1 1 1 2 2 2 0 PIN domain NPV_P10 PF05531.7 KLO11404.1 - 1.8 8.8 10.2 10 6.4 0.1 3.1 1 1 2 3 3 3 0 Nucleopolyhedrovirus P10 protein LOH1CR12 PF10158.4 KLO11404.1 - 1.9 8.2 6.0 6.8 6.5 0.1 2.7 1 1 1 2 2 2 0 Tumour suppressor protein DUF1664 PF07889.7 KLO11404.1 - 5.2 6.8 6.9 17 5.2 4.2 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) TPR_12 PF13424.1 KLO11405.1 - 4.1e-30 103.5 2.3 1.3e-07 31.3 0.0 5.7 2 2 4 6 6 6 6 Tetratricopeptide repeat TPR_10 PF13374.1 KLO11405.1 - 9.8e-28 95.2 0.5 0.00018 21.3 0.0 6.9 7 0 0 7 7 7 5 Tetratricopeptide repeat TcdB_N PF12918.2 KLO11405.1 - 1.9e-09 37.4 0.2 1.1 9.3 0.0 6.2 5 1 1 6 6 6 2 TcdB toxin N-terminal helical domain Apc5 PF12862.2 KLO11405.1 - 2.4e-07 30.4 2.1 4.5 7.1 0.1 5.6 2 2 3 5 5 5 2 Anaphase-promoting complex subunit 5 TPR_6 PF13174.1 KLO11405.1 - 4e-07 30.0 2.9 8.3 7.1 0.0 7.4 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_2 PF07719.12 KLO11405.1 - 1.6e-06 27.6 1.0 22 5.2 0.0 6.9 6 2 2 8 8 8 0 Tetratricopeptide repeat TPR_8 PF13181.1 KLO11405.1 - 0.00012 21.6 0.5 22 5.1 0.0 5.3 6 0 0 6 6 6 0 Tetratricopeptide repeat DUF3856 PF12968.2 KLO11405.1 - 0.00048 19.9 0.6 5.7 6.7 0.0 3.9 2 2 1 4 4 4 1 Domain of Unknown Function (DUF3856) TPR_5 PF12688.2 KLO11405.1 - 0.00095 19.1 0.9 3.3 7.7 0.0 4.7 2 2 3 5 5 5 1 Tetratrico peptide repeat Ded_cyto PF06920.8 KLO11405.1 - 0.033 13.5 0.2 11 5.3 0.0 3.4 3 1 1 4 4 4 0 Dedicator of cytokinesis Herpes_TK PF00693.13 KLO11405.1 - 0.045 12.9 0.0 7.6 5.6 0.0 3.3 4 0 0 4 4 4 0 Thymidine kinase from herpesvirus DUF2009 PF09418.5 KLO11405.1 - 0.081 11.6 0.0 0.13 11.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2009) Pkinase PF00069.20 KLO11408.1 - 5.7e-46 156.7 0.0 7.8e-46 156.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KLO11408.1 - 3.7e-26 91.7 0.0 4.9e-26 91.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KLO11408.1 - 1.3e-06 27.6 0.0 3e-06 26.4 0.0 1.6 1 1 0 1 1 1 1 Kinase-like APH PF01636.18 KLO11408.1 - 0.0014 18.3 0.0 0.0023 17.7 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.6 KLO11408.1 - 0.02 13.6 0.0 0.031 13.0 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Kdo PF06293.9 KLO11408.1 - 0.17 10.9 0.0 0.26 10.3 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Packaging_FI PF14000.1 KLO11409.1 - 0.037 14.2 0.4 0.037 14.2 0.3 2.4 1 1 1 2 2 2 0 DNA packaging protein FI Cwf_Cwc_15 PF04889.7 KLO11409.1 - 3.2 7.3 23.5 7.1 6.2 2.3 2.2 1 1 1 2 2 2 0 Cwf15/Cwc15 cell cycle control protein Plasmid_Txe PF06769.8 KLO11410.1 - 0.0068 16.1 0.1 0.02 14.7 0.0 1.7 1 1 1 2 2 2 1 Plasmid encoded toxin Txe TPR_10 PF13374.1 KLO11412.1 - 1.2e-54 180.7 3.2 4.7e-06 26.3 0.0 14.2 14 0 0 14 14 14 9 Tetratricopeptide repeat TPR_12 PF13424.1 KLO11412.1 - 2.7e-51 171.4 11.4 2e-07 30.8 0.1 9.8 7 2 4 11 11 10 10 Tetratricopeptide repeat TPR_11 PF13414.1 KLO11412.1 - 5.1e-16 58.0 17.8 0.043 13.4 0.1 9.4 5 2 6 11 11 11 4 TPR repeat Apc5 PF12862.2 KLO11412.1 - 1.5e-14 53.5 13.3 2.1 8.2 0.0 13.0 3 1 10 14 14 14 2 Anaphase-promoting complex subunit 5 DUF3856 PF12968.2 KLO11412.1 - 7.7e-14 51.7 2.7 0.073 12.8 0.0 6.2 5 1 1 6 6 6 4 Domain of Unknown Function (DUF3856) TPR_2 PF07719.12 KLO11412.1 - 9e-12 43.9 8.4 33 4.7 0.0 13.2 14 1 0 14 14 13 0 Tetratricopeptide repeat TPR_6 PF13174.1 KLO11412.1 - 1.6e-10 40.6 15.6 28 5.4 0.0 12.8 12 0 0 12 12 12 0 Tetratricopeptide repeat AAA_16 PF13191.1 KLO11412.1 - 4.6e-08 33.2 2.1 1.2e-07 31.9 0.0 2.8 2 1 0 2 2 2 1 AAA ATPase domain TPR_14 PF13428.1 KLO11412.1 - 7.1e-06 26.2 21.2 12 6.8 0.1 12.1 8 3 4 13 13 11 0 Tetratricopeptide repeat TPR_8 PF13181.1 KLO11412.1 - 9.6e-05 21.8 8.7 30 4.7 0.1 9.1 10 0 0 10 10 10 0 Tetratricopeptide repeat AAA_19 PF13245.1 KLO11412.1 - 0.00052 19.7 0.0 0.0015 18.2 0.0 1.7 1 0 0 1 1 1 1 Part of AAA domain TPR_16 PF13432.1 KLO11412.1 - 0.00075 20.1 13.5 1.6 9.4 0.2 8.1 7 3 3 10 10 7 1 Tetratricopeptide repeat NACHT PF05729.7 KLO11412.1 - 0.00079 19.1 0.0 0.0023 17.6 0.0 1.8 1 0 0 1 1 1 1 NACHT domain TPR_4 PF07721.9 KLO11412.1 - 0.0012 19.0 7.7 20 5.9 0.1 6.6 7 0 0 7 7 4 0 Tetratricopeptide repeat Phage_Treg PF04761.7 KLO11412.1 - 0.0033 17.1 0.0 1.5 8.6 0.0 3.3 3 0 0 3 3 3 1 Lactococcus bacteriophage putative transcription regulator NTPase_1 PF03266.10 KLO11412.1 - 0.015 14.9 0.0 0.035 13.8 0.0 1.6 1 0 0 1 1 1 0 NTPase DUF3475 PF11961.3 KLO11412.1 - 0.017 14.9 0.0 0.6 9.9 0.0 3.6 3 0 0 3 3 3 0 Domain of unknown function (DUF3475) Zeta_toxin PF06414.7 KLO11412.1 - 0.018 14.1 0.0 0.05 12.6 0.0 1.7 1 0 0 1 1 1 0 Zeta toxin AAA_17 PF13207.1 KLO11412.1 - 0.04 14.7 0.0 0.58 10.9 0.0 3.2 3 0 0 3 3 1 0 AAA domain DUF2299 PF10061.4 KLO11412.1 - 0.075 12.4 0.7 7 6.0 0.0 3.8 5 0 0 5 5 4 0 Uncharacterized conserved protein (DUF2299) DUF2075 PF09848.4 KLO11412.1 - 0.078 11.9 0.0 0.18 10.7 0.0 1.6 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_22 PF13401.1 KLO11412.1 - 0.079 13.0 0.0 1 9.5 0.0 3.0 2 0 0 2 2 2 0 AAA domain AAA PF00004.24 KLO11412.1 - 0.11 12.7 0.0 0.39 10.9 0.0 2.0 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Chordopox_A13L PF05961.6 KLO11412.1 - 0.13 12.1 0.0 0.4 10.6 0.0 1.8 1 0 0 1 1 1 0 Chordopoxvirus A13L protein CDC37_C PF08564.5 KLO11412.1 - 1 9.2 5.2 3.9 7.3 0.0 4.4 6 0 0 6 6 4 0 Cdc37 C terminal domain OmdA PF13376.1 KLO11412.1 - 3.2 7.4 8.3 13 5.5 0.2 4.5 5 0 0 5 5 4 0 Bacteriocin-protection, YdeI or OmpD-Associated LELP1 PF15042.1 KLO11413.1 - 7.1 6.8 15.5 7.6 6.7 10.7 1.1 1 0 0 1 1 1 0 Late cornified envelope-like proline-rich protein 1 UCR_UQCRX_QCR9 PF05365.7 KLO11414.1 - 0.22 11.1 1.1 0.27 10.8 0.8 1.1 1 0 0 1 1 1 0 Ubiquinol-cytochrome C reductase, UQCRX/QCR9 like RAI1 PF08652.6 KLO11415.1 - 3.4e-21 74.8 0.0 6.3e-21 73.9 0.0 1.5 1 0 0 1 1 1 1 RAI1 like PD-(D/E)XK nuclease Gpi16 PF04113.9 KLO11416.1 - 8.8e-130 433.3 0.0 7e-128 427.0 0.0 2.0 1 1 0 1 1 1 1 Gpi16 subunit, GPI transamidase component AAA PF00004.24 KLO11417.1 - 1.6e-86 287.1 0.0 4.8e-42 143.2 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 KLO11417.1 - 2.7e-13 49.8 0.2 2.5e-07 30.5 0.0 4.0 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 KLO11417.1 - 2.9e-11 43.5 0.0 0.00016 21.6 0.0 2.4 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_22 PF13401.1 KLO11417.1 - 3.9e-11 43.1 0.1 0.00036 20.6 0.0 4.4 2 2 0 2 2 2 2 AAA domain AAA_16 PF13191.1 KLO11417.1 - 4.3e-10 39.8 2.0 0.00067 19.6 0.0 3.8 3 1 1 4 4 4 2 AAA ATPase domain RuvB_N PF05496.7 KLO11417.1 - 2.1e-09 36.7 0.0 0.0042 16.1 0.0 3.3 3 0 0 3 3 3 2 Holliday junction DNA helicase ruvB N-terminus IstB_IS21 PF01695.12 KLO11417.1 - 1.3e-07 31.2 0.0 0.00034 20.0 0.0 2.5 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_25 PF13481.1 KLO11417.1 - 3e-07 30.0 1.7 0.03 13.7 0.0 4.3 2 2 1 4 4 4 2 AAA domain AAA_33 PF13671.1 KLO11417.1 - 5.6e-07 29.5 0.0 0.00069 19.4 0.0 2.6 2 0 0 2 2 2 2 AAA domain Zeta_toxin PF06414.7 KLO11417.1 - 1.3e-06 27.6 0.0 0.0029 16.7 0.0 2.3 2 0 0 2 2 2 2 Zeta toxin AAA_17 PF13207.1 KLO11417.1 - 2.1e-06 28.5 0.0 0.014 16.2 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_14 PF13173.1 KLO11417.1 - 2.7e-06 27.3 0.0 0.021 14.7 0.0 2.3 2 0 0 2 2 2 2 AAA domain TIP49 PF06068.8 KLO11417.1 - 2.1e-05 23.4 0.0 0.071 11.8 0.0 2.3 2 0 0 2 2 2 2 TIP49 C-terminus AAA_19 PF13245.1 KLO11417.1 - 2.6e-05 23.8 5.1 0.00086 19.0 0.1 3.8 4 1 0 4 4 3 1 Part of AAA domain Sigma54_activ_2 PF14532.1 KLO11417.1 - 5.3e-05 23.2 0.0 0.31 11.0 0.0 2.4 2 0 0 2 2 2 2 Sigma-54 interaction domain Mg_chelatase PF01078.16 KLO11417.1 - 0.00012 21.2 0.4 0.11 11.5 0.0 2.4 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI Bac_DnaA PF00308.13 KLO11417.1 - 0.00025 20.7 0.0 0.29 10.7 0.0 2.8 3 0 0 3 3 3 1 Bacterial dnaA protein RNA_helicase PF00910.17 KLO11417.1 - 0.00029 20.9 0.0 0.39 10.9 0.0 2.8 2 0 0 2 2 2 1 RNA helicase AAA_28 PF13521.1 KLO11417.1 - 0.00037 20.4 0.1 0.83 9.5 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_3 PF07726.6 KLO11417.1 - 0.00063 19.3 0.0 4.2 6.9 0.0 3.9 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) AAA_11 PF13086.1 KLO11417.1 - 0.00066 19.3 0.0 0.027 14.0 0.0 2.2 2 0 0 2 2 2 1 AAA domain Ribosomal_L50 PF10501.4 KLO11417.1 - 0.00068 19.5 0.0 0.0015 18.4 0.0 1.5 1 0 0 1 1 1 1 Ribosomal subunit 39S Arch_ATPase PF01637.13 KLO11417.1 - 0.00072 19.3 0.0 0.97 9.0 0.0 3.3 2 1 1 3 3 3 1 Archaeal ATPase AAA_18 PF13238.1 KLO11417.1 - 0.0049 17.1 0.1 0.53 10.6 0.0 2.8 3 0 0 3 3 2 1 AAA domain Sigma54_activat PF00158.21 KLO11417.1 - 0.0057 16.1 0.0 0.93 8.9 0.0 3.5 2 2 0 2 2 2 1 Sigma-54 interaction domain Rad17 PF03215.10 KLO11417.1 - 0.0067 15.1 0.0 0.032 12.9 0.0 1.9 2 0 0 2 2 2 1 Rad17 cell cycle checkpoint protein NACHT PF05729.7 KLO11417.1 - 0.016 14.8 0.0 0.39 10.3 0.0 2.9 3 1 0 3 3 3 0 NACHT domain ABC_tran PF00005.22 KLO11417.1 - 0.017 15.4 0.0 0.4 10.9 0.0 2.5 2 0 0 2 2 2 0 ABC transporter AAA_24 PF13479.1 KLO11417.1 - 0.022 14.3 1.6 0.14 11.7 0.0 2.6 3 0 0 3 3 2 0 AAA domain CDC48_2 PF02933.12 KLO11417.1 - 0.052 13.2 0.0 0.36 10.5 0.0 2.2 1 1 0 1 1 1 0 Cell division protein 48 (CDC48), domain 2 AAA_30 PF13604.1 KLO11417.1 - 0.062 12.8 0.0 0.16 11.5 0.0 1.8 1 0 0 1 1 1 0 AAA domain IPT PF01745.11 KLO11417.1 - 0.07 12.2 0.3 2.8 7.0 0.1 2.5 2 0 0 2 2 2 0 Isopentenyl transferase DUF815 PF05673.8 KLO11417.1 - 0.082 11.8 0.0 0.88 8.4 0.0 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF815) Parvo_NS1 PF01057.12 KLO11417.1 - 0.12 11.2 0.1 0.27 10.0 0.0 1.5 2 0 0 2 2 1 0 Parvovirus non-structural protein NS1 UPF0079 PF02367.12 KLO11417.1 - 0.18 11.4 0.1 3.8 7.1 0.0 2.4 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 Adeno_IVa2 PF02456.10 KLO11417.1 - 0.3 9.6 0.0 9 4.8 0.0 2.2 2 0 0 2 2 2 0 Adenovirus IVa2 protein ABC_tran PF00005.22 KLO11418.1 - 1e-34 119.7 0.0 2.1e-34 118.7 0.0 1.5 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.18 KLO11418.1 - 3.5e-31 108.6 11.2 4.5e-31 108.2 7.7 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region AAA_21 PF13304.1 KLO11418.1 - 1.1e-08 35.3 0.0 3.1e-05 24.1 0.0 2.5 1 1 0 1 1 1 1 AAA domain SMC_N PF02463.14 KLO11418.1 - 4.2e-07 29.4 0.0 0.0002 20.6 0.0 2.4 1 1 1 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_17 PF13207.1 KLO11418.1 - 0.002 18.9 0.0 0.0056 17.4 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 KLO11418.1 - 0.0038 17.3 0.1 0.046 13.8 0.1 2.3 1 1 0 1 1 1 1 AAA domain AAA PF00004.24 KLO11418.1 - 0.0043 17.2 0.0 0.036 14.2 0.0 2.2 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_29 PF13555.1 KLO11418.1 - 0.0051 16.3 0.0 0.013 15.0 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_14 PF13173.1 KLO11418.1 - 0.0057 16.5 0.0 0.041 13.7 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.9 KLO11418.1 - 0.0058 16.3 0.0 0.012 15.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 KLO11418.1 - 0.0094 15.9 0.0 0.027 14.4 0.0 1.8 1 1 0 1 1 1 1 AAA ATPase domain AAA_18 PF13238.1 KLO11418.1 - 0.024 14.9 0.0 0.13 12.6 0.0 2.2 2 0 0 2 2 2 0 AAA domain DUF258 PF03193.11 KLO11418.1 - 0.03 13.5 0.0 0.053 12.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 SbcCD_C PF13558.1 KLO11418.1 - 0.052 13.4 0.4 0.53 10.2 0.3 2.4 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_28 PF13521.1 KLO11418.1 - 0.057 13.3 0.0 0.14 12.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain ATP-synt_ab PF00006.20 KLO11418.1 - 0.071 12.5 0.0 0.13 11.7 0.0 1.4 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain Rad17 PF03215.10 KLO11418.1 - 0.096 11.3 0.0 0.17 10.5 0.0 1.3 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein MMR_HSR1 PF01926.18 KLO11418.1 - 0.13 12.2 0.0 0.35 10.8 0.0 1.8 1 0 0 1 1 1 0 50S ribosome-binding GTPase LRR_4 PF12799.2 KLO11419.1 - 2.5e-26 90.8 31.1 5e-08 32.3 0.6 9.4 7 3 4 11 11 11 9 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KLO11419.1 - 5.3e-17 61.3 30.8 4e-07 29.6 0.3 9.0 7 2 2 9 9 9 5 Leucine rich repeat LRR_1 PF00560.28 KLO11419.1 - 1.2e-13 49.0 39.9 0.28 11.3 0.4 11.3 11 1 1 12 12 12 7 Leucine Rich Repeat LRR_6 PF13516.1 KLO11419.1 - 5.1e-12 44.5 29.1 2.1 8.6 0.1 11.5 12 0 0 12 12 12 5 Leucine Rich repeat LRR_7 PF13504.1 KLO11419.1 - 3.9e-11 41.2 25.1 0.44 10.9 0.1 10.9 11 0 0 11 11 11 4 Leucine rich repeat Acetyltransf_3 PF13302.1 KLO11420.1 - 2.2e-07 31.1 0.0 3.3e-07 30.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Cyt-b5 PF00173.23 KLO11421.1 - 1.5e-18 66.3 0.0 1.9e-18 65.9 0.0 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain SUR7 PF06687.7 KLO11423.1 - 4.1e-20 72.2 10.8 8.2e-12 45.1 2.8 2.1 1 1 1 2 2 2 2 SUR7/PalI family Claudin_3 PF06653.6 KLO11423.1 - 0.27 10.9 8.6 1.7 8.3 5.9 2.0 1 1 0 1 1 1 0 Tight junction protein, Claudin-like TPPK_C PF12555.3 KLO11423.1 - 0.6 9.8 0.0 0.6 9.8 0.0 2.9 3 0 0 3 3 3 0 Thiamine pyrophosphokinase C terminal PMP22_Claudin PF00822.15 KLO11423.1 - 1.1 8.8 5.9 5.5 6.6 3.6 2.1 1 1 0 1 1 1 0 PMP-22/EMP/MP20/Claudin family Keratin_matx PF04579.7 KLO11424.1 - 0.026 14.8 0.1 0.032 14.5 0.1 1.4 1 0 0 1 1 1 0 Keratin, high-sulphur matrix protein Whi5 PF08528.6 KLO11425.1 - 0.003 17.1 0.0 0.005 16.4 0.0 1.4 1 0 0 1 1 1 1 Whi5 like MIP-T3 PF10243.4 KLO11425.1 - 2.7 6.3 15.0 4.9 5.4 10.4 1.4 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Pkinase PF00069.20 KLO11426.1 - 6.1e-57 192.7 0.0 4.8e-37 127.5 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 KLO11426.1 - 1.2e-50 171.9 0.0 7.3e-34 117.0 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase APH PF01636.18 KLO11426.1 - 6.5e-06 26.0 0.3 0.043 13.5 0.0 2.4 2 0 0 2 2 2 2 Phosphotransferase enzyme family RIO1 PF01163.17 KLO11426.1 - 5.6e-05 22.5 0.1 0.076 12.3 0.0 2.3 2 0 0 2 2 2 2 RIO1 family Seadorna_VP7 PF07387.6 KLO11426.1 - 0.00017 20.5 0.2 0.093 11.5 0.0 2.2 2 0 0 2 2 2 2 Seadornavirus VP7 WaaY PF06176.6 KLO11426.1 - 0.00096 18.4 0.1 0.01 15.0 0.0 2.4 3 0 0 3 3 3 1 Lipopolysaccharide core biosynthesis protein (WaaY) Kdo PF06293.9 KLO11426.1 - 0.0012 17.9 0.0 0.3 10.1 0.0 2.5 2 0 0 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.15 KLO11426.1 - 0.052 13.1 0.0 10 5.6 0.0 2.4 2 0 0 2 2 2 0 Choline/ethanolamine kinase Kinase-like PF14531.1 KLO11426.1 - 0.12 11.3 0.0 8.2 5.2 0.0 2.2 2 0 0 2 2 2 0 Kinase-like DUF1679 PF07914.6 KLO11426.1 - 0.18 10.3 0.0 6.3 5.3 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1679) STE3 PF02076.10 KLO11428.1 - 3.2e-49 167.5 10.5 4.5e-49 167.0 7.3 1.1 1 0 0 1 1 1 1 Pheromone A receptor STE3 PF02076.10 KLO11429.1 - 6.2e-48 163.3 14.9 8.2e-48 162.9 10.3 1.1 1 0 0 1 1 1 1 Pheromone A receptor Lon_C PF05362.8 KLO11431.1 - 3.1e-69 232.3 0.1 5.2e-69 231.6 0.1 1.4 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain LON PF02190.11 KLO11431.1 - 9.7e-35 120.1 0.1 2.1e-34 118.9 0.0 1.6 1 0 0 1 1 1 1 ATP-dependent protease La (LON) domain AAA PF00004.24 KLO11431.1 - 1.2e-21 77.3 0.0 3e-21 75.9 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 KLO11431.1 - 1.1e-07 31.7 0.0 2.2e-07 30.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 KLO11431.1 - 1.6e-06 28.1 0.0 4.2e-06 26.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) ChlI PF13541.1 KLO11431.1 - 1.8e-05 24.2 0.1 5e-05 22.8 0.0 1.8 1 1 0 1 1 1 1 Subunit ChlI of Mg-chelatase AAA_PrkA PF08298.6 KLO11431.1 - 2.5e-05 23.1 0.0 4.7e-05 22.2 0.0 1.3 1 0 0 1 1 1 1 PrkA AAA domain AAA_16 PF13191.1 KLO11431.1 - 4.7e-05 23.4 0.1 0.00085 19.3 0.0 2.7 3 0 0 3 3 3 1 AAA ATPase domain AAA_22 PF13401.1 KLO11431.1 - 0.00031 20.8 0.0 0.0039 17.3 0.0 2.5 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 KLO11431.1 - 0.00053 20.7 0.0 0.0022 18.8 0.0 2.1 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.7 KLO11431.1 - 0.00055 19.0 0.0 0.0028 16.7 0.0 2.0 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus RNA_helicase PF00910.17 KLO11431.1 - 0.00086 19.4 0.0 0.011 15.9 0.0 2.5 2 0 0 2 2 2 1 RNA helicase AAA_14 PF13173.1 KLO11431.1 - 0.0023 17.8 0.0 0.0081 16.0 0.0 1.9 2 1 0 2 2 2 1 AAA domain SKI PF01202.17 KLO11431.1 - 0.01 15.7 0.0 0.037 13.9 0.0 2.0 2 0 0 2 2 2 0 Shikimate kinase AAA_18 PF13238.1 KLO11431.1 - 0.012 15.9 0.9 0.053 13.8 0.0 2.3 2 0 0 2 2 2 0 AAA domain DUF258 PF03193.11 KLO11431.1 - 0.054 12.6 0.0 0.11 11.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_25 PF13481.1 KLO11431.1 - 0.063 12.6 0.0 0.15 11.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.12 KLO11431.1 - 0.087 12.2 0.0 0.18 11.2 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_21 PF13304.1 KLO11431.1 - 0.09 12.7 0.6 1.9 8.3 0.0 2.7 2 1 1 3 3 3 0 AAA domain DUF4589 PF15252.1 KLO11432.1 - 2.2 8.0 6.5 0.77 9.5 0.2 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4589) F-box-like PF12937.2 KLO11434.1 - 0.017 14.8 1.5 0.29 10.9 1.0 2.4 1 1 0 1 1 1 0 F-box-like GalKase_gal_bdg PF10509.4 KLO11436.1 - 1.6e-18 65.7 0.1 3.6e-18 64.5 0.0 1.6 1 0 0 1 1 1 1 Galactokinase galactose-binding signature GHMP_kinases_C PF08544.8 KLO11436.1 - 6.6e-11 42.2 0.0 1.7e-10 40.9 0.0 1.7 1 0 0 1 1 1 1 GHMP kinases C terminal GHMP_kinases_N PF00288.21 KLO11436.1 - 2.2e-10 40.4 0.5 8.9e-10 38.4 0.4 2.1 1 0 0 1 1 1 1 GHMP kinases N terminal domain ADH_zinc_N PF00107.21 KLO11437.1 - 2.6e-17 62.5 0.9 4.6e-17 61.7 0.4 1.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KLO11437.1 - 1.9e-10 40.4 0.0 3.5e-10 39.5 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 KLO11437.1 - 1e-06 29.6 0.4 1.8e-06 28.8 0.3 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.21 KLO11439.1 - 2.9e-17 62.4 0.1 5.9e-17 61.4 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KLO11439.1 - 7e-10 38.6 0.0 1.1e-09 37.9 0.0 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 KLO11439.1 - 2.7e-08 34.7 0.1 6.6e-08 33.5 0.0 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase LRR_4 PF12799.2 KLO11440.1 - 0.0045 16.5 2.2 2.2 7.9 0.1 3.7 4 0 0 4 4 4 2 Leucine Rich repeats (2 copies) ADH_zinc_N PF00107.21 KLO11441.1 - 3.3e-19 68.7 0.1 5.8e-19 67.9 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KLO11441.1 - 6.4e-09 35.5 0.1 1.1e-08 34.8 0.1 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 KLO11441.1 - 1.6e-08 35.5 0.1 3.2e-08 34.5 0.1 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase LRR_4 PF12799.2 KLO11442.1 - 0.016 14.7 0.1 5.5 6.7 0.0 2.8 2 0 0 2 2 2 0 Leucine Rich repeats (2 copies) RAP1 PF07218.6 KLO11444.1 - 5.9 4.8 10.3 15 3.5 7.2 1.6 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) mRNA_triPase PF02940.10 KLO11455.1 - 3.6e-54 183.7 0.1 4.2e-54 183.5 0.0 1.1 1 0 0 1 1 1 1 mRNA capping enzyme, beta chain CRAL_TRIO PF00650.15 KLO11456.1 - 3.4e-30 104.6 0.0 5.2e-30 104.0 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 KLO11456.1 - 2.7e-09 36.9 0.0 6.7e-09 35.7 0.0 1.7 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain DUF4357 PF14267.1 KLO11456.1 - 0.058 12.9 0.0 0.14 11.8 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4357) Peptidase_M3_N PF08439.5 KLO11456.1 - 0.1 12.6 0.0 0.27 11.2 0.0 1.7 1 0 0 1 1 1 0 Oligopeptidase F Zip PF02535.17 KLO11457.1 - 1.4e-34 119.5 6.8 6.5e-34 117.3 4.7 1.9 1 1 0 1 1 1 1 ZIP Zinc transporter Cation_efflux PF01545.16 KLO11457.1 - 0.0071 15.4 0.0 0.0071 15.4 0.0 2.3 1 1 1 2 2 2 1 Cation efflux family DNA_ligase_OB_2 PF14743.1 KLO11458.1 - 2.2e-30 104.1 0.2 3.9e-30 103.3 0.2 1.4 1 0 0 1 1 1 1 DNA ligase OB-like domain DNA_ligase_A_M PF01068.16 KLO11458.1 - 2.6e-17 62.8 0.0 4.5e-17 62.0 0.0 1.4 1 0 0 1 1 1 1 ATP dependent DNA ligase domain RNA_ligase PF09414.5 KLO11458.1 - 0.063 13.0 0.0 0.27 10.9 0.0 1.9 2 0 0 2 2 2 0 RNA ligase Nop14 PF04147.7 KLO11458.1 - 5.4 4.7 12.0 7.3 4.3 8.3 1.1 1 0 0 1 1 1 0 Nop14-like family TFCD_C PF12612.3 KLO11459.1 - 6.4e-29 100.7 0.0 3.1e-28 98.5 0.0 2.3 2 0 0 2 2 2 1 Tubulin folding cofactor D C terminal HEAT PF02985.17 KLO11459.1 - 0.0067 16.4 11.7 0.29 11.3 0.0 6.4 7 0 0 7 7 7 1 HEAT repeat HEAT_2 PF13646.1 KLO11459.1 - 0.11 12.7 0.1 0.11 12.7 0.0 4.6 4 1 1 5 5 5 0 HEAT repeats HEAT_EZ PF13513.1 KLO11459.1 - 0.13 12.8 12.2 2.7 8.6 0.0 6.3 6 0 0 6 6 6 0 HEAT-like repeat ATP-synt_C PF00137.16 KLO11460.1 - 2.8e-25 87.9 31.3 1.2e-14 53.8 8.4 2.1 2 0 0 2 2 2 2 ATP synthase subunit C Ribosomal_L6 PF00347.18 KLO11461.1 - 8.2e-21 74.2 0.0 7.6e-12 45.5 0.0 2.6 2 1 0 2 2 2 2 Ribosomal protein L6 MARVEL PF01284.18 KLO11462.1 - 1.2e-08 34.8 7.2 1.8e-08 34.2 5.0 1.2 1 0 0 1 1 1 1 Membrane-associating domain DUF2304 PF10066.4 KLO11462.1 - 0.49 10.2 4.2 0.44 10.4 0.5 2.1 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2304) DUF2890 PF11081.3 KLO11464.1 - 0.28 11.2 4.1 0.36 10.8 2.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) CDC45 PF02724.9 KLO11464.1 - 0.36 8.8 2.3 0.37 8.7 1.6 1.0 1 0 0 1 1 1 0 CDC45-like protein DUF3682 PF12446.3 KLO11464.1 - 1.4 9.1 6.7 2.5 8.4 4.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3682) Mak16 PF04874.9 KLO11464.1 - 3.3 7.8 14.1 5.2 7.2 9.7 1.2 1 0 0 1 1 1 0 Mak16 protein C-terminal region BUD22 PF09073.5 KLO11465.1 - 3.2e-61 207.6 27.6 5.1e-61 207.0 19.2 1.3 1 0 0 1 1 1 1 BUD22 DUF3813 PF12758.2 KLO11465.1 - 0.41 10.8 5.0 3.1 7.9 0.2 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3813) DUF2361 PF10153.4 KLO11465.1 - 1.8 8.8 17.9 2.1 8.5 8.4 3.1 3 0 0 3 3 3 0 Uncharacterised conserved protein (DUF2361) zf-ribbon_3 PF13248.1 KLO11466.1 - 0.53 9.5 8.4 0.97 8.7 5.8 1.4 1 0 0 1 1 1 0 zinc-ribbon domain zf-HIT PF04438.11 KLO11466.1 - 0.64 9.7 11.2 1.2 8.8 7.8 1.4 1 0 0 1 1 1 0 HIT zinc finger F-box-like PF12937.2 KLO11469.1 - 4.5e-07 29.4 0.0 1.8e-06 27.5 0.0 2.1 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 KLO11469.1 - 5.5e-06 25.8 0.1 0.0011 18.5 0.0 3.1 2 0 0 2 2 2 2 F-box domain tRNA_bind PF01588.15 KLO11471.1 - 8.7e-28 96.0 0.0 1.5e-27 95.2 0.0 1.4 1 0 0 1 1 1 1 Putative tRNA binding domain GST_C_3 PF14497.1 KLO11471.1 - 3.3e-07 30.6 0.0 8.4e-07 29.3 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 KLO11471.1 - 3.7e-06 26.8 0.0 9.4e-06 25.5 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 KLO11471.1 - 1.6e-05 24.6 0.0 3.3e-05 23.7 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain NARP1 PF12569.3 KLO11471.1 - 0.19 10.4 5.5 0.27 9.9 3.8 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Scm3 PF10384.4 KLO11472.1 - 9.3e-09 34.6 0.1 9.3e-09 34.6 0.1 1.9 2 0 0 2 2 2 1 Centromere protein Scm3 DPBB_1 PF03330.13 KLO11473.1 - 1.9e-05 24.5 0.1 6.4e-05 22.8 0.1 2.0 1 1 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel DPBB_1 PF03330.13 KLO11474.1 - 0.00045 20.1 0.0 0.0014 18.5 0.0 2.0 1 1 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel F-box-like PF12937.2 KLO11475.1 - 7.8e-07 28.7 2.6 1.3e-06 27.9 0.1 2.7 3 0 0 3 3 3 1 F-box-like F-box PF00646.28 KLO11475.1 - 0.087 12.5 2.3 12 5.7 0.1 3.1 3 0 0 3 3 3 0 F-box domain Sugarporin_N PF11471.3 KLO11476.1 - 0.16 11.6 0.2 0.21 11.2 0.2 1.2 1 0 0 1 1 1 0 Maltoporin periplasmic N-terminal extension PP2C PF00481.16 KLO11478.1 - 4.1e-74 249.1 0.1 1.4e-73 247.4 0.1 1.7 2 0 0 2 2 2 1 Protein phosphatase 2C DUF605 PF04652.11 KLO11478.1 - 0.49 9.7 14.0 0.75 9.1 9.7 1.2 1 0 0 1 1 1 0 Vta1 like CS PF04969.11 KLO11479.1 - 8.9e-09 35.7 0.0 4.3e-08 33.5 0.0 2.2 2 0 0 2 2 2 1 CS domain VWA_2 PF13519.1 KLO11480.1 - 6.9e-13 49.0 0.0 2.1e-12 47.4 0.0 1.7 2 0 0 2 2 2 1 von Willebrand factor type A domain VWA PF00092.23 KLO11480.1 - 3.1e-05 23.7 0.0 5.7e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain Med25_VWA PF11265.3 KLO11480.1 - 0.0015 17.6 0.0 0.0026 16.8 0.0 1.3 1 0 0 1 1 1 1 Mediator complex subunit 25 von Willebrand factor type A Integrin_beta PF00362.13 KLO11480.1 - 0.095 11.5 0.0 0.14 11.0 0.0 1.2 1 0 0 1 1 1 0 Integrin, beta chain Miro PF08477.8 KLO11481.1 - 8.5e-35 119.8 0.0 6e-18 65.4 0.0 2.5 2 0 0 2 2 2 2 Miro-like protein Ras PF00071.17 KLO11481.1 - 1.5e-31 108.9 0.0 4.7e-20 71.5 0.0 2.2 2 0 0 2 2 2 2 Ras family EF_assoc_1 PF08355.7 KLO11481.1 - 6.9e-30 102.1 0.3 1.2e-29 101.4 0.2 1.4 1 0 0 1 1 1 1 EF hand associated EF_assoc_2 PF08356.7 KLO11481.1 - 2.3e-24 84.9 0.0 6.3e-24 83.5 0.0 1.8 1 0 0 1 1 1 1 EF hand associated EF-hand_1 PF00036.27 KLO11481.1 - 8.3e-11 40.3 2.6 0.00025 20.1 0.1 2.9 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.1 KLO11481.1 - 8.3e-11 40.8 0.8 0.00077 19.1 0.1 2.9 2 0 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.1 KLO11481.1 - 3.1e-09 36.8 0.3 0.00089 19.3 0.1 3.1 3 0 0 3 3 2 2 EF-hand domain pair Arf PF00025.16 KLO11481.1 - 3.8e-09 36.0 0.0 0.00098 18.3 0.0 2.6 2 1 0 2 2 2 2 ADP-ribosylation factor family EF-hand_5 PF13202.1 KLO11481.1 - 6.4e-08 31.5 4.6 0.00056 19.1 0.2 2.6 2 0 0 2 2 2 2 EF hand AAA_22 PF13401.1 KLO11481.1 - 8.7e-08 32.3 0.0 0.0018 18.4 0.0 3.0 3 1 0 3 3 2 2 AAA domain MMR_HSR1 PF01926.18 KLO11481.1 - 1.1e-07 31.7 0.0 0.0026 17.6 0.0 2.5 2 0 0 2 2 2 2 50S ribosome-binding GTPase Dynamin_N PF00350.18 KLO11481.1 - 3.3e-06 27.0 0.9 0.093 12.5 0.0 3.3 2 1 1 3 3 3 2 Dynamin family AAA_16 PF13191.1 KLO11481.1 - 5.4e-06 26.5 0.0 0.034 14.1 0.0 2.4 2 0 0 2 2 2 2 AAA ATPase domain MobB PF03205.9 KLO11481.1 - 2.3e-05 24.1 0.2 0.064 12.9 0.0 2.4 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B NACHT PF05729.7 KLO11481.1 - 8.4e-05 22.2 0.0 0.21 11.2 0.0 2.5 2 0 0 2 2 2 2 NACHT domain Arch_ATPase PF01637.13 KLO11481.1 - 0.00011 22.0 0.1 0.024 14.3 0.0 2.4 2 0 0 2 2 2 1 Archaeal ATPase ABC_tran PF00005.22 KLO11481.1 - 0.00015 22.1 0.0 0.11 12.7 0.0 2.5 2 0 0 2 2 2 1 ABC transporter AAA_24 PF13479.1 KLO11481.1 - 0.00017 21.2 0.0 0.35 10.4 0.0 2.3 2 0 0 2 2 2 2 AAA domain DUF258 PF03193.11 KLO11481.1 - 0.00037 19.7 0.0 0.044 12.9 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function, DUF258 ATP_bind_1 PF03029.12 KLO11481.1 - 0.00059 19.4 1.2 5.8 6.3 0.0 4.1 4 0 0 4 4 4 0 Conserved hypothetical ATP binding protein AAA_29 PF13555.1 KLO11481.1 - 0.0008 18.8 0.1 0.16 11.5 0.0 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain RNA_helicase PF00910.17 KLO11481.1 - 0.00091 19.3 0.0 0.96 9.6 0.0 2.6 2 0 0 2 2 2 1 RNA helicase SRPRB PF09439.5 KLO11481.1 - 0.0013 18.0 0.1 1.2 8.3 0.0 2.9 2 1 0 2 2 2 1 Signal recognition particle receptor beta subunit AAA_28 PF13521.1 KLO11481.1 - 0.0013 18.6 0.0 0.8 9.6 0.0 2.5 2 0 0 2 2 2 1 AAA domain EF-hand_10 PF14788.1 KLO11481.1 - 0.0016 18.0 0.5 0.2 11.3 0.0 2.6 2 0 0 2 2 2 1 EF hand cobW PF02492.14 KLO11481.1 - 0.002 17.5 0.0 0.62 9.4 0.0 3.0 3 0 0 3 3 3 1 CobW/HypB/UreG, nucleotide-binding domain AAA_14 PF13173.1 KLO11481.1 - 0.0021 17.9 0.0 3 7.7 0.0 2.5 2 0 0 2 2 2 0 AAA domain Septin PF00735.13 KLO11481.1 - 0.0027 16.7 0.0 0.2 10.6 0.0 2.3 2 0 0 2 2 2 1 Septin GTP_EFTU PF00009.22 KLO11481.1 - 0.0031 16.9 0.3 1.3 8.3 0.0 3.7 3 1 1 4 4 4 1 Elongation factor Tu GTP binding domain Guanylate_kin PF00625.16 KLO11481.1 - 0.0032 16.9 0.2 0.015 14.7 0.1 2.0 2 0 0 2 2 2 1 Guanylate kinase AAA_33 PF13671.1 KLO11481.1 - 0.0034 17.2 0.0 1.1 9.1 0.0 2.5 2 0 0 2 2 2 1 AAA domain EF-hand_8 PF13833.1 KLO11481.1 - 0.005 16.4 0.5 0.34 10.5 0.0 2.8 2 0 0 2 2 2 1 EF-hand domain pair PduV-EutP PF10662.4 KLO11481.1 - 0.0057 16.1 0.0 0.46 9.9 0.0 2.5 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation FtsK_SpoIIIE PF01580.13 KLO11481.1 - 0.0063 16.0 0.0 1.7 8.0 0.0 2.3 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA_17 PF13207.1 KLO11481.1 - 0.0083 16.9 0.2 3.1 8.6 0.0 3.2 3 0 0 3 3 2 0 AAA domain NB-ARC PF00931.17 KLO11481.1 - 0.01 14.7 0.0 1.6 7.5 0.0 2.3 2 0 0 2 2 2 0 NB-ARC domain AAA PF00004.24 KLO11481.1 - 0.012 15.8 0.0 1.7 8.8 0.0 2.3 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Viral_helicase1 PF01443.13 KLO11481.1 - 0.012 15.1 0.1 0.22 11.0 0.0 2.3 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase AAA_18 PF13238.1 KLO11481.1 - 0.012 15.8 0.0 4.2 7.6 0.0 2.6 2 0 0 2 2 2 0 AAA domain ATP-synt_ab PF00006.20 KLO11481.1 - 0.018 14.5 0.0 5.4 6.4 0.0 2.1 1 1 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain SPARC_Ca_bdg PF10591.4 KLO11481.1 - 0.021 14.8 0.9 1 9.3 0.0 2.8 3 0 0 3 3 2 0 Secreted protein acidic and rich in cysteine Ca binding region AIG1 PF04548.11 KLO11481.1 - 0.031 13.3 0.0 0.069 12.2 0.0 1.6 1 0 0 1 1 1 0 AIG1 family G-alpha PF00503.15 KLO11481.1 - 0.037 12.7 0.0 5.5 5.5 0.0 2.7 3 0 0 3 3 3 0 G-protein alpha subunit Gtr1_RagA PF04670.7 KLO11481.1 - 0.059 12.4 0.0 7.9 5.5 0.0 2.4 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region AAA_10 PF12846.2 KLO11481.1 - 0.071 12.5 0.0 6.2 6.1 0.0 2.3 2 0 0 2 2 2 0 AAA-like domain AAA_25 PF13481.1 KLO11481.1 - 0.078 12.3 0.0 2.2 7.6 0.0 2.3 2 0 0 2 2 2 0 AAA domain DUF815 PF05673.8 KLO11481.1 - 0.086 11.7 0.0 2.8 6.7 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF815) Zeta_toxin PF06414.7 KLO11481.1 - 0.12 11.4 0.0 6.2 5.8 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin NTPase_1 PF03266.10 KLO11481.1 - 0.14 11.8 0.2 1.7 8.3 0.2 2.3 2 0 0 2 2 2 0 NTPase AAA_5 PF07728.9 KLO11481.1 - 0.16 11.6 0.1 4 7.1 0.0 2.6 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_32 PF13654.1 KLO11481.1 - 0.23 10.0 0.1 4.3 5.8 0.0 2.4 3 0 0 3 3 3 0 AAA domain Pkinase PF00069.20 KLO11482.1 - 3e-52 177.3 0.0 1.9e-25 89.4 0.0 3.4 3 0 0 3 3 3 3 Protein kinase domain HGTP_anticodon2 PF12745.2 KLO11482.1 - 4.1e-28 98.2 2.5 1.4e-27 96.5 0.0 2.4 2 0 0 2 2 2 1 Anticodon binding domain of tRNAs Pkinase_Tyr PF07714.12 KLO11482.1 - 1.3e-23 83.3 0.0 1.2e-10 40.9 0.0 3.5 3 0 0 3 3 3 3 Protein tyrosine kinase RWD PF05773.17 KLO11482.1 - 4.3e-15 55.5 2.2 6.9e-15 54.9 0.0 2.5 2 0 0 2 2 2 1 RWD domain Peptidase_C71 PF12386.3 KLO11482.1 - 0.19 11.1 0.0 0.41 10.0 0.0 1.5 1 0 0 1 1 1 0 Pseudomurein endo-isopeptidase Pei DIOX_N PF14226.1 KLO11483.1 - 1.4e-22 80.3 0.0 2e-22 79.9 0.0 1.2 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 KLO11483.1 - 0.003 17.8 0.0 0.0081 16.4 0.0 1.9 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily YTH PF04146.10 KLO11484.1 - 6.2e-49 165.2 0.0 1.9e-48 163.6 0.0 1.7 1 1 0 1 1 1 1 YT521-B-like domain RRM_1 PF00076.17 KLO11484.1 - 0.39 10.3 0.0 3.5 7.3 0.0 2.1 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CAF1 PF04857.15 KLO11488.1 - 1.8e-67 227.4 0.0 2.9e-67 226.7 0.0 1.3 1 1 0 1 1 1 1 CAF1 family ribonuclease GPI-anchored PF10342.4 KLO11489.1 - 3.1e-09 37.2 2.3 3.7e-09 36.9 1.6 1.1 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family DUF4448 PF14610.1 KLO11489.1 - 0.0077 15.7 0.1 0.0077 15.7 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) SH3_9 PF14604.1 KLO11490.1 - 3e-23 81.1 0.8 2.3e-12 46.2 0.1 2.4 2 0 0 2 2 2 2 Variant SH3 domain SH3_1 PF00018.23 KLO11490.1 - 2.1e-18 65.4 0.4 1.3e-08 34.1 0.3 2.7 2 1 0 2 2 2 2 SH3 domain SH3_2 PF07653.12 KLO11490.1 - 4.6e-18 64.4 0.1 6.6e-09 35.1 0.0 2.4 2 0 0 2 2 2 2 Variant SH3 domain FCH PF00611.18 KLO11490.1 - 7e-15 54.9 0.1 7e-15 54.9 0.1 3.7 3 1 1 4 4 4 1 Fes/CIP4, and EFC/F-BAR homology domain C1_1 PF00130.17 KLO11490.1 - 1.9e-13 49.8 1.6 3.4e-13 49.1 1.1 1.4 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) SH3_3 PF08239.6 KLO11490.1 - 0.007 16.5 0.0 0.014 15.5 0.0 1.5 1 0 0 1 1 1 1 Bacterial SH3 domain PHD_2 PF13831.1 KLO11490.1 - 0.067 12.5 1.1 0.15 11.4 0.8 1.5 1 0 0 1 1 1 0 PHD-finger Antitoxin-MazE PF04014.13 KLO11490.1 - 0.16 11.7 0.7 0.48 10.2 0.1 2.0 2 0 0 2 2 2 0 Antidote-toxin recognition MazE Pyridoxal_deC PF00282.14 KLO11491.1 - 3.2e-109 364.7 0.0 3.9e-109 364.5 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain DPBB_1 PF03330.13 KLO11493.1 - 1.7e-06 27.8 0.3 1.8e-05 24.6 0.1 2.5 1 1 1 2 2 2 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Barwin PF00967.12 KLO11493.1 - 0.00041 20.0 0.1 0.00064 19.3 0.0 1.3 1 0 0 1 1 1 1 Barwin family Lactamase_B_2 PF12706.2 KLO11494.1 - 3.4e-08 33.2 0.1 9.3e-08 31.8 0.0 1.7 1 0 0 1 1 1 1 Beta-lactamase superfamily domain DRMBL PF07522.9 KLO11494.1 - 0.0031 17.5 1.2 0.0057 16.6 0.0 2.0 2 0 0 2 2 2 1 DNA repair metallo-beta-lactamase PRP1_N PF06424.7 KLO11495.1 - 9.4e-48 161.9 11.6 2.2e-46 157.5 2.1 2.5 2 0 0 2 2 2 2 PRP1 splicing factor, N-terminal TPR_14 PF13428.1 KLO11495.1 - 4.2e-27 92.1 24.3 0.012 16.2 0.0 14.2 6 3 8 14 14 14 9 Tetratricopeptide repeat TPR_19 PF14559.1 KLO11495.1 - 1.4e-19 70.1 13.8 9.1e-06 25.9 0.1 9.1 9 1 0 9 9 9 4 Tetratricopeptide repeat TPR_16 PF13432.1 KLO11495.1 - 7.1e-19 67.9 22.0 0.0003 21.3 0.0 8.0 7 1 1 8 8 8 3 Tetratricopeptide repeat TPR_2 PF07719.12 KLO11495.1 - 1e-06 28.1 9.0 0.27 11.2 0.0 8.3 9 0 0 9 9 9 2 Tetratricopeptide repeat TPR_11 PF13414.1 KLO11495.1 - 2.6e-06 26.9 9.3 0.25 10.9 0.0 8.0 6 2 2 8 8 8 1 TPR repeat TPR_12 PF13424.1 KLO11495.1 - 7.4e-06 25.8 0.5 0.64 9.9 0.0 5.3 4 3 2 6 6 6 2 Tetratricopeptide repeat TPR_17 PF13431.1 KLO11495.1 - 0.00031 20.7 0.1 54 4.3 0.0 7.1 9 0 0 9 9 8 0 Tetratricopeptide repeat Suf PF05843.9 KLO11495.1 - 0.00075 19.3 0.1 0.82 9.3 0.0 3.8 4 0 0 4 4 4 1 Suppressor of forked protein (Suf) TPR_8 PF13181.1 KLO11495.1 - 0.0012 18.5 1.4 0.86 9.5 0.0 4.8 6 0 0 6 6 5 1 Tetratricopeptide repeat TPR_7 PF13176.1 KLO11495.1 - 0.0022 17.6 0.0 0.89 9.5 0.0 5.1 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_6 PF13174.1 KLO11495.1 - 0.0028 17.9 13.1 3 8.5 0.0 7.9 10 0 0 10 10 9 1 Tetratricopeptide repeat TPR_1 PF00515.23 KLO11495.1 - 0.077 12.6 3.4 3.4 7.4 0.0 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_9 PF13371.1 KLO11495.1 - 0.13 12.1 8.7 3 7.7 0.0 5.9 6 1 0 6 6 6 0 Tetratricopeptide repeat Sugar_tr PF00083.19 KLO11496.1 - 8.8e-34 116.8 22.6 1.1e-33 116.4 15.6 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KLO11496.1 - 2e-28 99.1 29.7 2e-28 99.1 20.6 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily Curlin_rpt PF07012.7 KLO11496.1 - 3.2 7.5 5.0 1.6 8.4 0.4 2.4 2 0 0 2 2 2 0 Curlin associated repeat DUF1996 PF09362.5 KLO11497.1 - 3.1e-53 180.8 0.1 4.9e-53 180.2 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) BTB PF00651.26 KLO11498.1 - 5.8e-08 32.7 0.0 9.8e-08 31.9 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain Nucleo_P87 PF07267.6 KLO11499.1 - 6.3 5.3 9.2 10 4.6 5.3 2.1 2 0 0 2 2 2 0 Nucleopolyhedrovirus capsid protein P87 SNF2_N PF00176.18 KLO11500.1 - 2e-22 79.3 0.0 4.7e-15 55.1 0.0 2.4 2 0 0 2 2 2 2 SNF2 family N-terminal domain DNA_methylase PF00145.12 KLO11500.1 - 3.5e-13 49.3 0.0 3.5e-13 49.3 0.0 2.9 3 0 0 3 3 3 1 C-5 cytosine-specific DNA methylase N2227 PF07942.7 KLO11500.1 - 0.2 10.6 0.0 0.35 9.7 0.0 1.3 1 0 0 1 1 1 0 N2227-like protein Rad60-SLD PF11976.3 KLO11502.1 - 0.0076 15.9 0.0 0.12 12.0 0.0 2.4 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like Pkinase_Tyr PF07714.12 KLO11503.1 - 2.3e-34 118.6 0.0 3.4e-34 118.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 KLO11503.1 - 1.7e-28 99.5 0.0 2.7e-28 98.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.1 KLO11503.1 - 0.0013 17.7 0.0 0.0021 17.1 0.0 1.2 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.17 KLO11503.1 - 0.0036 16.6 0.0 0.0063 15.8 0.0 1.3 1 0 0 1 1 1 1 RIO1 family APH PF01636.18 KLO11503.1 - 0.0048 16.6 0.0 0.51 10.0 0.0 2.3 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.9 KLO11503.1 - 0.072 12.1 0.0 0.14 11.2 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family LisH PF08513.6 KLO11506.1 - 0.00016 21.2 0.2 0.00031 20.3 0.0 1.6 2 0 0 2 2 2 1 LisH p450 PF00067.17 KLO11507.1 - 2.9e-74 250.2 0.0 3.2e-74 250.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Mt_ATP-synt_B PF05405.9 KLO11508.1 - 1.3e-42 144.9 9.2 1.6e-42 144.7 6.4 1.1 1 0 0 1 1 1 1 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) DUF1931 PF09123.6 KLO11508.1 - 0.0014 18.6 2.7 0.38 10.6 0.5 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF1931) DASH_Duo1 PF08651.5 KLO11508.1 - 0.056 13.0 1.5 6 6.5 0.0 2.9 2 1 1 3 3 3 0 DASH complex subunit Duo1 Ank_2 PF12796.2 KLO11509.1 - 1e-39 134.7 0.0 2.8e-09 37.2 0.0 7.4 4 2 2 6 6 6 5 Ankyrin repeats (3 copies) Ank_5 PF13857.1 KLO11509.1 - 1.1e-26 92.2 1.1 9.5e-06 25.7 0.1 9.5 8 3 2 10 10 10 6 Ankyrin repeats (many copies) Ank PF00023.25 KLO11509.1 - 2.3e-25 87.0 11.0 0.0012 18.5 0.0 11.3 12 0 0 12 12 12 5 Ankyrin repeat Ank_3 PF13606.1 KLO11509.1 - 2.5e-24 82.8 6.2 0.012 15.8 0.0 11.5 14 0 0 14 14 14 5 Ankyrin repeat Ank_4 PF13637.1 KLO11509.1 - 1.2e-16 60.7 1.1 0.017 15.6 0.0 8.2 7 2 3 10 10 10 5 Ankyrin repeats (many copies) Rad60-SLD PF11976.3 KLO11510.1 - 2.2e-06 27.2 0.0 4.2e-06 26.3 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.18 KLO11510.1 - 6.3e-06 25.5 0.0 1.2e-05 24.5 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family YukD PF08817.5 KLO11510.1 - 0.017 15.7 0.0 0.053 14.0 0.0 1.9 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukD ubiquitin PF00240.18 KLO11512.1 - 0.045 13.1 0.0 0.091 12.1 0.0 1.6 1 0 0 1 1 1 0 Ubiquitin family SKG6 PF08693.5 KLO11513.1 - 1.4e-06 27.4 3.1 3.4e-06 26.2 2.1 1.6 1 0 0 1 1 1 1 Transmembrane alpha-helix domain TMEM154 PF15102.1 KLO11513.1 - 0.034 13.8 6.1 0.32 10.7 4.3 2.2 1 1 0 1 1 1 0 TMEM154 protein family Med12-LCEWAV PF12145.3 KLO11513.1 - 0.038 12.4 3.4 0.088 11.2 2.4 1.6 1 1 0 1 1 1 0 Eukaryotic Mediator 12 subunit domain Rax2 PF12768.2 KLO11513.1 - 0.24 10.5 4.1 2.6 7.2 2.3 2.6 2 1 0 2 2 2 0 Cortical protein marker for cell polarity DUF1180 PF06679.7 KLO11513.1 - 2.6 7.9 10.9 1.9 8.3 6.3 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF1180) EphA2_TM PF14575.1 KLO11514.1 - 0.0036 17.6 0.1 0.0074 16.6 0.0 1.4 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain Rax2 PF12768.2 KLO11514.1 - 0.0084 15.3 0.0 0.01 15.0 0.0 1.2 1 0 0 1 1 1 1 Cortical protein marker for cell polarity Utp8 PF10395.4 KLO11514.1 - 0.01 14.1 0.2 0.013 13.8 0.1 1.1 1 0 0 1 1 1 0 Utp8 family DUF1191 PF06697.7 KLO11514.1 - 0.031 13.0 0.0 0.05 12.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1191) TMEM154 PF15102.1 KLO11514.1 - 0.048 13.3 0.5 0.095 12.3 0.4 1.5 1 0 0 1 1 1 0 TMEM154 protein family Syndecan PF01034.15 KLO11514.1 - 0.053 13.1 0.0 0.1 12.2 0.0 1.4 1 0 0 1 1 1 0 Syndecan domain Shisa PF13908.1 KLO11514.1 - 0.14 12.3 0.1 0.21 11.7 0.1 1.2 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator Syndecan PF01034.15 KLO11515.1 - 0.0055 16.3 0.1 0.01 15.4 0.0 1.3 1 0 0 1 1 1 1 Syndecan domain Rifin_STEVOR PF02009.11 KLO11515.1 - 0.0078 15.8 1.5 0.013 15.2 1.0 1.2 1 0 0 1 1 1 1 Rifin/stevor family BTB PF00651.26 KLO11516.1 - 4.9e-06 26.4 0.0 8.6e-06 25.7 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain ATP-synt_ab PF00006.20 KLO11518.1 - 1.8e-70 236.8 0.0 3.1e-70 236.0 0.0 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 KLO11518.1 - 9.7e-24 84.0 0.2 2.7e-23 82.6 0.0 1.9 2 0 0 2 2 2 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 KLO11518.1 - 3.3e-19 68.8 1.5 8.7e-19 67.5 1.1 1.8 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain HAS-barrel PF09378.5 KLO11518.1 - 6.1e-05 22.8 1.0 0.00016 21.5 0.6 1.8 2 0 0 2 2 2 1 HAS barrel domain Ribosomal_L21p PF00829.16 KLO11519.1 - 2.1e-15 56.6 0.1 2.6e-15 56.3 0.1 1.1 1 0 0 1 1 1 1 Ribosomal prokaryotic L21 protein FF PF01846.14 KLO11520.1 - 1.5e-28 98.4 9.2 1.3e-10 41.0 0.1 6.0 5 0 0 5 5 5 5 FF domain WW PF00397.21 KLO11520.1 - 3e-14 52.5 14.2 1.4e-07 31.2 1.9 2.7 2 0 0 2 2 2 2 WW domain TarH PF02203.10 KLO11520.1 - 0.24 11.2 2.9 0.63 9.8 0.1 2.4 2 0 0 2 2 2 0 Tar ligand binding domain homologue Brix PF04427.13 KLO11521.1 - 1.2e-41 142.5 0.0 1.7e-41 141.9 0.0 1.3 1 0 0 1 1 1 1 Brix domain zf-ZPR1 PF03367.8 KLO11522.1 - 1.6e-102 339.4 0.4 7.5e-53 177.9 0.0 3.1 2 1 1 3 3 3 3 ZPR1 zinc-finger domain DZR PF12773.2 KLO11522.1 - 0.0063 16.3 4.5 0.33 10.8 0.1 3.1 2 1 0 2 2 2 1 Double zinc ribbon HypA PF01155.14 KLO11522.1 - 0.017 14.7 2.5 2.9 7.6 0.1 2.5 2 0 0 2 2 2 0 Hydrogenase expression/synthesis hypA family zinc_ribbon_2 PF13240.1 KLO11522.1 - 0.023 14.1 12.6 1.4 8.5 0.1 4.3 4 0 0 4 4 4 0 zinc-ribbon domain Polysacc_deac_2 PF04748.8 KLO11522.1 - 0.13 11.2 0.0 0.26 10.2 0.0 1.4 1 0 0 1 1 1 0 Divergent polysaccharide deacetylase DUF2688 PF10892.3 KLO11522.1 - 0.17 11.5 0.9 11 5.7 0.1 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF2688) Zn-ribbon_8 PF09723.5 KLO11522.1 - 0.21 11.5 7.5 1.8 8.6 0.1 4.1 4 0 0 4 4 4 0 Zinc ribbon domain zf-ribbon_3 PF13248.1 KLO11522.1 - 1.8 7.8 11.3 3.1 7.1 1.4 3.7 3 1 0 3 3 3 0 zinc-ribbon domain OrfB_Zn_ribbon PF07282.6 KLO11522.1 - 3.3 7.4 6.5 49 3.6 0.1 3.7 4 1 0 4 4 4 0 Putative transposase DNA-binding domain MFS_1 PF07690.11 KLO11523.1 - 4.4e-29 101.2 27.0 4.4e-29 101.2 18.7 1.7 1 1 1 2 2 2 1 Major Facilitator Superfamily CCSMST1 PF15013.1 KLO11523.1 - 0.083 12.8 0.1 4.7 7.1 0.0 2.7 2 0 0 2 2 2 0 CCSMST1 family HMG_CoA_synt_C PF08540.5 KLO11524.1 - 1.5e-85 287.1 0.3 4.5e-85 285.5 0.2 1.7 1 1 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase C terminal HMG_CoA_synt_N PF01154.12 KLO11524.1 - 4.5e-85 283.5 0.1 7.1e-85 282.9 0.1 1.3 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase N terminal ADH_zinc_N PF00107.21 KLO11526.1 - 4.4e-09 35.9 0.0 7.5e-09 35.2 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KLO11526.1 - 2.2e-06 27.3 0.0 4.4e-06 26.4 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain CoA_binding_2 PF13380.1 KLO11526.1 - 0.083 13.0 0.1 0.18 11.9 0.1 1.6 1 0 0 1 1 1 0 CoA binding domain DUF1752 PF08550.5 KLO11527.1 - 4.8e-09 35.6 7.4 1.1e-08 34.5 5.1 1.6 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) MFS_1 PF07690.11 KLO11529.1 - 2.2e-24 85.8 29.1 2.2e-24 85.8 20.2 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily EMP24_GP25L PF01105.19 KLO11530.1 - 1.2e-48 165.2 0.2 1.4e-48 165.0 0.1 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD VPS9 PF02204.13 KLO11531.1 - 1.5e-31 108.4 0.2 2.6e-31 107.7 0.2 1.4 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain CUE PF02845.11 KLO11531.1 - 6.6e-07 28.6 0.1 3.6e-06 26.3 0.0 2.1 2 0 0 2 2 2 1 CUE domain DMA PF03474.9 KLO11531.1 - 0.0055 16.5 0.0 0.011 15.5 0.0 1.5 1 0 0 1 1 1 1 DMRTA motif Peptidase_C12 PF01088.16 KLO11532.1 - 3.3e-49 166.9 0.0 4e-49 166.7 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 ABC_membrane PF00664.18 KLO11533.1 - 4.1e-70 236.3 29.5 9.1e-39 133.5 5.9 2.5 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 KLO11533.1 - 2.1e-54 183.5 0.0 5.1e-32 111.0 0.0 2.6 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.14 KLO11533.1 - 2.4e-09 36.7 0.0 0.0015 17.8 0.0 4.1 2 2 1 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.1 KLO11533.1 - 2.7e-06 27.5 0.1 0.052 13.5 0.0 2.9 2 0 0 2 2 2 2 AAA ATPase domain Miro PF08477.8 KLO11533.1 - 2e-05 25.0 0.1 0.31 11.5 0.0 2.6 2 0 0 2 2 2 2 Miro-like protein MMR_HSR1 PF01926.18 KLO11533.1 - 8e-05 22.5 0.5 0.43 10.5 0.0 3.1 3 0 0 3 3 2 2 50S ribosome-binding GTPase AAA_21 PF13304.1 KLO11533.1 - 0.00021 21.3 0.1 0.86 9.5 0.0 3.7 2 1 0 2 2 2 1 AAA domain AAA_25 PF13481.1 KLO11533.1 - 0.00036 20.0 0.0 1 8.7 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.1 KLO11533.1 - 0.00038 19.9 1.0 0.18 11.3 0.0 2.7 2 0 0 2 2 2 1 P-loop containing region of AAA domain DUF258 PF03193.11 KLO11533.1 - 0.0023 17.1 1.1 0.55 9.4 0.1 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_23 PF13476.1 KLO11533.1 - 0.0031 17.8 0.4 3.2 8.0 0.1 2.5 2 0 0 2 2 2 2 AAA domain Zeta_toxin PF06414.7 KLO11533.1 - 0.0068 15.5 0.5 0.73 8.8 0.0 2.5 2 0 0 2 2 2 1 Zeta toxin ABC_ATPase PF09818.4 KLO11533.1 - 0.0084 14.7 1.3 0.014 14.0 0.0 1.9 2 0 0 2 2 2 1 Predicted ATPase of the ABC class ArgK PF03308.11 KLO11533.1 - 0.012 14.4 0.0 3.9 6.1 0.0 2.5 2 0 0 2 2 2 0 ArgK protein cobW PF02492.14 KLO11533.1 - 0.013 14.9 1.5 0.2 11.0 0.1 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain NB-ARC PF00931.17 KLO11533.1 - 0.014 14.2 0.4 0.74 8.6 0.1 3.1 2 1 0 2 2 2 0 NB-ARC domain T2SE PF00437.15 KLO11533.1 - 0.015 14.2 0.0 3.4 6.5 0.0 2.5 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_30 PF13604.1 KLO11533.1 - 0.02 14.5 0.3 0.93 9.0 0.0 2.7 3 0 0 3 3 3 0 AAA domain Dynamin_N PF00350.18 KLO11533.1 - 0.034 13.9 2.6 2.1 8.1 0.4 2.5 2 0 0 2 2 2 0 Dynamin family AAA_22 PF13401.1 KLO11533.1 - 0.11 12.6 1.6 5.3 7.1 0.1 3.3 2 1 0 2 2 2 0 AAA domain Arch_ATPase PF01637.13 KLO11533.1 - 0.13 11.9 0.0 3.1 7.4 0.0 2.7 2 1 0 2 2 2 0 Archaeal ATPase UPF0079 PF02367.12 KLO11533.1 - 0.13 11.8 0.5 0.45 10.1 0.1 1.9 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 DUF87 PF01935.12 KLO11533.1 - 0.21 11.3 5.2 1.3 8.7 0.1 2.8 3 0 0 3 3 3 0 Domain of unknown function DUF87 MS_channel PF00924.13 KLO11534.1 - 4.3e-17 62.1 0.5 6.9e-17 61.4 0.4 1.3 1 0 0 1 1 1 1 Mechanosensitive ion channel EF-hand_1 PF00036.27 KLO11534.1 - 7.3e-06 24.9 0.4 2.1e-05 23.4 0.0 2.1 2 0 0 2 2 2 1 EF hand EF-hand_6 PF13405.1 KLO11534.1 - 0.00013 21.5 0.3 0.00072 19.2 0.0 2.4 2 0 0 2 2 2 1 EF-hand domain EF-hand_5 PF13202.1 KLO11534.1 - 0.00061 19.0 0.1 0.002 17.4 0.0 1.9 1 0 0 1 1 1 1 EF hand EF-hand_7 PF13499.1 KLO11534.1 - 0.00081 19.4 0.1 0.0027 17.7 0.0 1.9 2 0 0 2 2 2 1 EF-hand domain pair Neur_chan_memb PF02932.11 KLO11534.1 - 0.6 9.9 3.9 0.7 9.7 0.0 2.7 3 0 0 3 3 3 0 Neurotransmitter-gated ion-channel transmembrane region DUF1129 PF06570.6 KLO11534.1 - 1.5 8.1 4.2 0.76 9.0 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1129) Glycos_transf_2 PF00535.21 KLO11535.1 - 2.7e-25 88.9 0.0 3.6e-25 88.5 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.1 KLO11535.1 - 1.1e-11 44.9 0.0 2.4e-11 43.8 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.4 KLO11535.1 - 0.0029 16.7 0.0 0.0037 16.3 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_4 PF13704.1 KLO11535.1 - 0.0051 17.0 0.0 0.011 16.0 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferase family 2 PFK PF00365.15 KLO11535.1 - 0.033 13.1 0.1 0.12 11.2 0.0 1.7 1 1 1 2 2 2 0 Phosphofructokinase Rcd1 PF04078.8 KLO11536.1 - 1e-128 427.7 4.9 1.2e-128 427.5 3.4 1.0 1 0 0 1 1 1 1 Cell differentiation family, Rcd1-like Pkinase PF00069.20 KLO11538.1 - 8e-40 136.6 0.0 1e-39 136.2 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KLO11538.1 - 3e-32 111.7 0.0 3.8e-32 111.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KLO11538.1 - 2e-05 23.6 0.0 3.8e-05 22.7 0.0 1.5 1 1 0 1 1 1 1 Kinase-like RIO1 PF01163.17 KLO11538.1 - 0.0092 15.3 0.0 0.017 14.4 0.0 1.4 1 0 0 1 1 1 1 RIO1 family APH PF01636.18 KLO11538.1 - 0.018 14.8 0.0 0.025 14.3 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family A_deaminase PF00962.17 KLO11539.1 - 1.3e-25 90.0 0.0 1.6e-25 89.7 0.0 1.0 1 0 0 1 1 1 1 Adenosine/AMP deaminase Thr_synth_N PF14821.1 KLO11540.1 - 9e-29 99.3 0.0 4e-28 97.2 0.0 2.1 2 0 0 2 2 2 1 Threonine synthase N terminus PALP PF00291.20 KLO11540.1 - 3.3e-20 72.5 0.0 7.2e-20 71.4 0.0 1.5 1 1 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme PRMT5 PF05185.11 KLO11541.1 - 1.4e-149 498.8 0.0 8.7e-148 492.9 0.0 2.0 1 1 0 1 1 1 1 PRMT5 arginine-N-methyltransferase Met_10 PF02475.11 KLO11541.1 - 0.1 12.1 0.0 0.16 11.5 0.0 1.2 1 0 0 1 1 1 0 Met-10+ like-protein Macoilin PF09726.4 KLO11542.1 - 5 5.2 12.9 5.7 5.0 8.9 1.0 1 0 0 1 1 1 0 Transmembrane protein TMEM154 PF15102.1 KLO11543.1 - 9.4e-06 25.3 0.7 9.4e-06 25.3 0.5 2.1 2 0 0 2 2 2 1 TMEM154 protein family Rifin_STEVOR PF02009.11 KLO11543.1 - 0.0016 18.1 0.0 0.0024 17.5 0.0 1.2 1 0 0 1 1 1 1 Rifin/stevor family VSP PF03302.8 KLO11543.1 - 0.0052 15.4 2.8 0.0082 14.8 2.0 1.2 1 0 0 1 1 1 1 Giardia variant-specific surface protein Herpes_gE PF02480.11 KLO11543.1 - 0.0069 14.6 0.2 0.012 13.9 0.1 1.3 1 0 0 1 1 1 1 Alphaherpesvirus glycoprotein E Phage_GP20 PF06810.6 KLO11544.1 - 0.0092 15.4 0.2 0.02 14.3 0.1 1.6 1 0 0 1 1 1 1 Phage minor structural protein GP20 ECM11 PF15463.1 KLO11544.1 - 0.013 15.7 3.0 0.039 14.2 2.1 1.8 1 0 0 1 1 1 0 Extracellular mutant protein 11 DUF2597 PF10772.4 KLO11544.1 - 0.053 13.4 0.0 0.099 12.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2597) HsdM_N PF12161.3 KLO11544.1 - 0.21 12.0 1.8 0.37 11.2 1.3 1.4 1 0 0 1 1 1 0 HsdM N-terminal domain Fork_head PF00250.13 KLO11546.1 - 1.7e-25 88.8 0.1 2e-25 88.6 0.1 1.1 1 0 0 1 1 1 1 Fork head domain TPR_11 PF13414.1 KLO11547.1 - 6e-18 64.2 4.7 6.9e-14 51.2 3.3 2.7 1 1 1 2 2 2 2 TPR repeat TPR_1 PF00515.23 KLO11547.1 - 3.6e-09 35.8 2.6 0.004 16.6 0.1 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_16 PF13432.1 KLO11547.1 - 4.5e-09 36.7 1.5 0.0016 19.0 0.0 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.12 KLO11547.1 - 2.5e-08 33.1 3.2 0.012 15.5 0.1 3.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.1 KLO11547.1 - 1.7e-06 28.2 0.9 1.1e-05 25.6 0.1 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.1 KLO11547.1 - 2.5e-05 24.5 2.0 0.0081 16.7 0.4 3.1 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.1 KLO11547.1 - 0.00038 20.3 3.0 0.017 15.0 0.8 3.4 2 1 2 4 4 4 2 Tetratricopeptide repeat TPR_17 PF13431.1 KLO11547.1 - 0.0077 16.3 2.3 4.7 7.6 0.3 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.1 KLO11547.1 - 0.011 15.4 0.4 6.3 6.8 0.0 3.4 2 1 0 2 2 2 0 Tetratricopeptide repeat Phage_P2_GpE PF06528.7 KLO11547.1 - 0.016 14.6 0.5 0.12 11.8 0.1 2.4 2 0 0 2 2 2 0 Phage P2 GpE Serglycin PF04360.7 KLO11547.1 - 0.1 12.3 1.5 0.26 11.0 1.0 1.6 1 0 0 1 1 1 0 Serglycin Fis1_TPR_C PF14853.1 KLO11547.1 - 0.29 11.0 2.7 18 5.2 0.0 3.1 3 0 0 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat LRR_6 PF13516.1 KLO11548.1 - 3.6e-05 23.3 1.8 1.2 9.4 0.0 4.4 4 0 0 4 4 4 2 Leucine Rich repeat LRR_8 PF13855.1 KLO11548.1 - 0.00055 19.6 0.2 0.51 10.1 0.0 2.9 3 0 0 3 3 3 2 Leucine rich repeat LRR_4 PF12799.2 KLO11548.1 - 0.0022 17.5 1.2 0.046 13.3 0.0 3.2 2 1 1 3 3 3 1 Leucine Rich repeats (2 copies) Pkinase_Tyr PF07714.12 KLO11549.1 - 2e-31 108.9 0.0 2.7e-31 108.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 KLO11549.1 - 8.7e-29 100.4 0.0 1.2e-28 100.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.18 KLO11549.1 - 0.00059 19.6 0.0 0.0012 18.5 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Fructosamin_kin PF03881.9 KLO11549.1 - 0.15 10.9 0.0 0.22 10.4 0.0 1.1 1 0 0 1 1 1 0 Fructosamine kinase Sporozoite_P67 PF05642.6 KLO11552.1 - 1.1 7.1 16.4 1.3 6.8 11.4 1.0 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Arylesterase PF01731.15 KLO11553.1 - 0.00045 20.1 0.1 0.056 13.4 0.0 2.9 2 1 1 3 3 3 1 Arylesterase NHL PF01436.16 KLO11553.1 - 0.009 15.9 0.1 5.1 7.2 0.0 4.1 4 0 0 4 4 4 1 NHL repeat Str_synth PF03088.11 KLO11553.1 - 0.13 12.3 0.0 3 7.9 0.0 2.3 2 0 0 2 2 2 0 Strictosidine synthase Na_Ca_ex PF01699.19 KLO11555.1 - 5.1e-47 158.9 35.9 3.1e-28 98.1 4.7 2.7 3 0 0 3 3 3 2 Sodium/calcium exchanger protein ThiF PF00899.16 KLO11557.1 - 1.6e-41 141.3 0.1 2.4e-41 140.7 0.0 1.3 1 0 0 1 1 1 1 ThiF family MoeZ_MoeB PF05237.8 KLO11557.1 - 1.6e-25 88.4 0.2 4.1e-25 87.1 0.1 1.7 2 0 0 2 2 2 1 MoeZ/MoeB domain Rhodanese PF00581.15 KLO11557.1 - 1.2e-09 38.5 0.0 2e-09 37.7 0.0 1.4 1 0 0 1 1 1 1 Rhodanese-like domain Shikimate_DH PF01488.15 KLO11557.1 - 3.2e-06 27.2 0.1 5.4e-05 23.3 0.1 2.2 1 1 1 2 2 2 1 Shikimate / quinate 5-dehydrogenase UbiA PF01040.13 KLO11559.1 - 4.3e-25 88.3 20.8 6.2e-25 87.8 14.4 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family zf-Tim10_DDP PF02953.10 KLO11560.1 - 2.6e-24 84.2 2.0 3e-24 84.0 1.4 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger Cytomega_TRL10 PF06084.6 KLO11560.1 - 0.033 13.9 0.7 0.037 13.8 0.5 1.1 1 0 0 1 1 1 0 Cytomegalovirus TRL10 protein DUF3398 PF11878.3 KLO11560.1 - 0.056 13.2 0.0 0.065 13.0 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3398) FANCI_S3 PF14677.1 KLO11560.1 - 0.063 12.6 0.2 0.074 12.4 0.1 1.2 1 0 0 1 1 1 0 FANCI solenoid 3 AflR PF08493.5 KLO11560.1 - 0.1 11.6 0.1 0.11 11.5 0.1 1.1 1 0 0 1 1 1 0 Aflatoxin regulatory protein DnaJ PF00226.26 KLO11561.1 - 6.5e-24 83.4 3.3 6.5e-24 83.4 2.3 2.6 2 1 0 2 2 2 1 DnaJ domain zf-C2H2_2 PF12756.2 KLO11561.1 - 1.5e-07 31.4 1.5 0.0079 16.2 0.2 2.7 2 0 0 2 2 2 2 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.3 KLO11561.1 - 3e-07 30.3 3.2 4.9e-07 29.6 0.3 2.6 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 KLO11561.1 - 3.4e-07 30.2 5.1 3.9e-07 30.0 0.5 2.6 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.1 KLO11561.1 - 3.7e-05 23.4 1.0 0.27 11.1 0.1 2.5 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.21 KLO11561.1 - 8.1e-05 22.7 5.8 0.085 13.2 0.2 3.5 2 1 1 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KLO11561.1 - 0.0031 17.7 4.6 1.2 9.5 0.1 3.4 2 1 0 2 2 2 2 C2H2-type zinc finger PGA2 PF07543.7 KLO11561.1 - 3.7 7.3 16.6 0.19 11.5 0.8 3.6 3 0 0 3 3 3 0 Protein trafficking PGA2 DnaJ PF00226.26 KLO11562.1 - 2.3e-24 84.9 1.4 4.2e-24 84.0 0.9 1.5 1 0 0 1 1 1 1 DnaJ domain Sigma70_ner PF04546.8 KLO11562.1 - 0.034 13.7 6.7 0.018 14.6 2.0 2.2 3 0 0 3 3 3 0 Sigma-70, non-essential region Metal_resist PF13801.1 KLO11562.1 - 0.081 12.9 0.8 9.5 6.2 0.0 2.7 2 1 0 2 2 2 0 Heavy-metal resistance Rft-1 PF04506.8 KLO11563.1 - 4.8e-80 269.4 19.2 9e-80 268.5 13.3 1.3 1 1 0 1 1 1 1 Rft protein CCSMST1 PF15013.1 KLO11563.1 - 0.2 11.6 1.3 1.3 8.9 0.2 2.7 1 1 1 2 2 2 0 CCSMST1 family RNase_PH PF01138.16 KLO11564.1 - 4.9e-35 120.7 0.3 2.1e-34 118.7 0.0 1.9 2 0 0 2 2 2 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.10 KLO11564.1 - 0.00022 21.1 0.0 0.00039 20.2 0.0 1.5 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 Homeobox PF00046.24 KLO11565.1 - 1.9e-18 65.7 4.1 3.3e-18 65.0 2.8 1.4 1 0 0 1 1 1 1 Homeobox domain RRM_1 PF00076.17 KLO11566.1 - 4.4e-18 64.6 0.1 6.9e-18 64.0 0.1 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KLO11566.1 - 1.4e-15 57.0 0.1 2.2e-15 56.4 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) U1snRNP70_N PF12220.3 KLO11566.1 - 6.8e-15 55.1 2.9 1.7e-14 53.8 2.0 1.7 1 1 0 1 1 1 1 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal RRM_5 PF13893.1 KLO11566.1 - 8.9e-10 38.2 0.0 1.5e-09 37.5 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) COX6B PF02297.12 KLO11567.1 - 9.8e-19 67.1 4.7 1.2e-18 66.9 3.2 1.1 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb CHCH PF06747.8 KLO11567.1 - 0.052 13.4 0.6 0.12 12.3 0.4 1.7 1 1 0 1 1 1 0 CHCH domain UPF0203 PF05254.7 KLO11567.1 - 0.67 9.8 6.0 2.7 7.8 0.5 2.1 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0203) Prp18 PF02840.10 KLO11568.1 - 6.8e-58 194.6 0.4 1e-57 194.0 0.0 1.4 2 0 0 2 2 2 1 Prp18 domain PRP4 PF08799.6 KLO11568.1 - 6.4e-11 41.3 6.6 6.4e-11 41.3 4.5 2.1 2 0 0 2 2 2 1 pre-mRNA processing factor 4 (PRP4) like Frag1 PF10277.4 KLO11569.1 - 4.7e-31 107.9 5.9 4.7e-31 107.9 4.1 3.0 3 2 0 3 3 3 1 Frag1/DRAM/Sfk1 family Exo_endo_phos PF03372.18 KLO11569.1 - 0.043 13.7 0.0 0.091 12.6 0.0 1.5 1 0 0 1 1 1 0 Endonuclease/Exonuclease/phosphatase family Adaptin_N PF01602.15 KLO11570.1 - 2.2e-122 409.0 0.0 3e-122 408.6 0.0 1.1 1 0 0 1 1 1 1 Adaptin N terminal region HEAT_2 PF13646.1 KLO11570.1 - 1.5e-10 41.1 1.4 0.00042 20.5 0.0 4.9 3 1 2 5 5 5 3 HEAT repeats HEAT PF02985.17 KLO11570.1 - 3.5e-08 32.8 4.4 0.16 12.1 0.0 7.0 7 0 0 7 7 7 2 HEAT repeat HEAT_EZ PF13513.1 KLO11570.1 - 8.4e-06 26.1 0.3 0.08 13.4 0.0 3.9 3 0 0 3 3 3 2 HEAT-like repeat Cohesin_HEAT PF12765.2 KLO11570.1 - 0.058 13.3 0.4 0.33 10.9 0.0 2.4 2 0 0 2 2 2 0 HEAT repeat associated with sister chromatid cohesion Cnd1 PF12717.2 KLO11570.1 - 0.087 12.6 4.7 0.51 10.1 0.0 3.2 3 0 0 3 3 3 0 non-SMC mitotic condensation complex subunit 1 zf-RING_2 PF13639.1 KLO11571.1 - 0.00069 19.3 0.5 0.0016 18.1 0.4 1.6 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 KLO11571.1 - 0.0058 16.7 0.1 0.011 15.8 0.1 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_5 PF14634.1 KLO11571.1 - 0.015 15.0 0.2 0.029 14.1 0.1 1.4 1 0 0 1 1 1 0 zinc-RING finger domain GATA PF00320.22 KLO11572.1 - 2.7e-14 52.1 4.2 5.8e-14 51.1 2.9 1.6 1 0 0 1 1 1 1 GATA zinc finger DUF22 PF01629.11 KLO11572.1 - 0.046 13.2 0.0 0.078 12.4 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function DUF22 IncA PF04156.9 KLO11573.1 - 0.14 11.7 0.3 0.19 11.2 0.2 1.3 1 0 0 1 1 1 0 IncA protein Tmemb_18A PF09771.4 KLO11573.1 - 0.15 12.0 1.4 0.19 11.7 1.0 1.1 1 0 0 1 1 1 0 Transmembrane protein 188 RELT PF12606.3 KLO11573.1 - 3.4 6.8 7.9 0.25 10.5 2.0 1.7 2 0 0 2 2 2 0 Tumour necrosis factor receptor superfamily member 19 Fungal_trans PF04082.13 KLO11574.1 - 4e-22 78.3 0.2 6.3e-22 77.6 0.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KLO11574.1 - 3.2e-07 30.1 15.0 5.6e-07 29.3 10.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PapC_N PF13954.1 KLO11574.1 - 0.017 14.6 0.0 0.037 13.6 0.0 1.5 1 0 0 1 1 1 0 PapC N-terminal domain cobW PF02492.14 KLO11575.1 - 1.6e-40 138.4 0.0 2e-40 138.1 0.0 1.1 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain MobB PF03205.9 KLO11575.1 - 0.00083 19.0 0.0 0.0024 17.5 0.0 1.8 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_22 PF13401.1 KLO11575.1 - 0.00092 19.3 0.0 0.0039 17.3 0.0 2.0 1 1 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.18 KLO11575.1 - 0.018 14.9 0.0 0.031 14.2 0.0 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase SRP54 PF00448.17 KLO11575.1 - 0.02 14.3 0.2 0.054 12.9 0.1 1.7 1 1 0 1 1 1 0 SRP54-type protein, GTPase domain DUF1574 PF07611.6 KLO11575.1 - 0.022 13.6 0.1 0.05 12.4 0.0 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1574) DUF258 PF03193.11 KLO11575.1 - 0.023 13.9 0.0 0.037 13.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 CobW_C PF07683.9 KLO11575.1 - 0.036 13.7 0.0 0.061 13.0 0.0 1.4 1 0 0 1 1 1 0 Cobalamin synthesis protein cobW C-terminal domain AAA_16 PF13191.1 KLO11575.1 - 0.061 13.3 0.0 0.085 12.8 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain Pox_A32 PF04665.7 KLO11575.1 - 0.085 12.1 0.1 0.34 10.1 0.0 1.8 2 0 0 2 2 2 0 Poxvirus A32 protein AAA_33 PF13671.1 KLO11575.1 - 0.13 12.1 0.0 0.23 11.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.1 KLO11575.1 - 0.14 11.7 0.2 0.6 9.6 0.0 2.1 2 0 0 2 2 2 0 P-loop containing region of AAA domain DUF4604 PF15377.1 KLO11576.1 - 1.1e-25 90.6 22.6 1.5e-25 90.2 15.7 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4604) Dyp_perox PF04261.7 KLO11577.1 - 7.5e-08 31.4 0.0 3.8e-07 29.1 0.0 2.1 2 1 0 2 2 2 1 Dyp-type peroxidase family Abhydrolase_6 PF12697.2 KLO11578.1 - 5.1e-11 42.8 3.0 3e-06 27.2 1.1 2.0 1 1 1 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KLO11578.1 - 2e-10 40.6 0.2 2.6e-10 40.2 0.2 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S15 PF02129.13 KLO11578.1 - 5e-05 22.8 1.6 0.00013 21.4 0.4 1.9 1 1 0 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_1 PF00561.15 KLO11578.1 - 5e-05 22.9 0.2 0.0021 17.6 0.1 2.3 2 0 0 2 2 2 1 alpha/beta hydrolase fold VirJ PF06057.6 KLO11578.1 - 0.049 13.4 0.0 0.19 11.5 0.0 2.0 1 1 0 1 1 1 0 Bacterial virulence protein (VirJ) PE-PPE PF08237.6 KLO11578.1 - 0.15 11.4 0.1 0.34 10.2 0.0 1.6 2 0 0 2 2 2 0 PE-PPE domain DnaJ PF00226.26 KLO11579.1 - 8.9e-26 89.4 1.4 1.6e-25 88.6 1.0 1.4 1 0 0 1 1 1 1 DnaJ domain CTDII PF01556.13 KLO11579.1 - 5.4e-20 71.0 0.9 4.7e-17 61.6 0.1 2.4 2 0 0 2 2 2 2 DnaJ C terminal domain DUF202 PF02656.10 KLO11580.1 - 1.4e-09 37.9 3.5 1.4e-09 37.9 2.4 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF202) DUF2339 PF10101.4 KLO11580.1 - 0.0014 16.9 1.3 0.0017 16.7 0.9 1.0 1 0 0 1 1 1 1 Predicted membrane protein (DUF2339) DUF4383 PF14325.1 KLO11580.1 - 0.022 14.7 1.7 0.03 14.3 1.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4383) EamA PF00892.15 KLO11580.1 - 0.051 13.6 1.0 0.051 13.6 0.7 1.8 2 0 0 2 2 2 0 EamA-like transporter family CoA_binding_3 PF13727.1 KLO11580.1 - 0.062 13.1 3.1 0.09 12.5 2.1 1.3 1 0 0 1 1 1 0 CoA-binding domain NfeD PF01957.13 KLO11580.1 - 0.51 10.4 3.7 0.41 10.7 0.2 2.3 1 1 2 3 3 3 0 NfeD-like C-terminal, partner-binding MerC PF03203.9 KLO11580.1 - 0.99 9.7 3.3 0.29 11.5 0.4 1.5 2 0 0 2 2 2 0 MerC mercury resistance protein MgtE PF01769.11 KLO11581.1 - 0.18 12.1 6.8 0.064 13.5 1.6 2.6 2 1 0 2 2 2 0 Divalent cation transporter MARVEL PF01284.18 KLO11582.1 - 9.3e-10 38.4 11.0 2.5e-09 37.0 7.6 1.8 1 1 0 1 1 1 1 Membrane-associating domain TMEM154 PF15102.1 KLO11582.1 - 0.031 13.9 1.3 0.073 12.7 0.9 1.5 1 0 0 1 1 1 0 TMEM154 protein family Mak10 PF04112.8 KLO11583.1 - 0.00043 19.5 0.4 0.00087 18.5 0.3 1.4 1 0 0 1 1 1 1 Mak10 subunit, NatC N(alpha)-terminal acetyltransferase DEAD PF00270.24 KLO11584.1 - 0.0089 15.5 0.0 0.0098 15.4 0.0 1.0 1 0 0 1 1 1 1 DEAD/DEAH box helicase Acetyltransf_2 PF00797.12 KLO11586.1 - 0.00057 19.5 0.0 0.0068 15.9 0.0 2.1 1 1 0 1 1 1 1 N-acetyltransferase Pkinase PF00069.20 KLO11587.1 - 1.1e-37 129.6 0.0 1.7e-37 128.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KLO11587.1 - 4.2e-36 124.3 0.0 6.1e-36 123.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 KLO11587.1 - 0.024 14.3 0.0 0.052 13.2 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 KLO11587.1 - 0.078 11.7 0.0 0.12 11.2 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Peptidase_M50B PF13398.1 KLO11588.1 - 1.7e-40 138.5 16.4 2.3e-40 138.1 11.4 1.1 1 0 0 1 1 1 1 Peptidase M50B-like AmiS_UreI PF02293.10 KLO11588.1 - 0.016 14.9 6.9 0.034 13.7 4.8 1.7 1 0 0 1 1 1 0 AmiS/UreI family transporter PIG-P PF08510.7 KLO11588.1 - 7.9 6.1 10.0 0.38 10.4 2.5 1.9 2 0 0 2 2 2 0 PIG-P STE3 PF02076.10 KLO11589.1 - 4.3e-62 209.7 9.0 5.1e-62 209.5 6.3 1.0 1 0 0 1 1 1 1 Pheromone A receptor Arteri_Gl PF00951.13 KLO11589.1 - 0.036 13.6 0.2 0.085 12.4 0.2 1.5 1 0 0 1 1 1 0 Arterivirus GL envelope glycoprotein Histone PF00125.19 KLO11590.1 - 3.9e-26 90.9 0.0 4.8e-26 90.6 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 KLO11590.1 - 3.4e-06 26.9 0.0 4.5e-06 26.6 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone FCH PF00611.18 KLO11591.1 - 1.9e-08 34.3 0.0 8.7e-08 32.2 0.0 2.3 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain DEP PF00610.16 KLO11591.1 - 2e-08 33.8 0.0 3.6e-08 33.0 0.0 1.4 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) RhoGAP PF00620.22 KLO11591.1 - 2.1e-08 33.9 0.0 7.1e-08 32.2 0.0 1.9 2 0 0 2 2 2 1 RhoGAP domain Ribonucleas_3_3 PF14622.1 KLO11592.1 - 3.8e-08 33.3 0.0 7.6e-08 32.3 0.0 1.5 1 0 0 1 1 1 1 Ribonuclease-III-like Ribonuclease_3 PF00636.21 KLO11592.1 - 1e-06 29.1 0.0 1.6e-06 28.5 0.0 1.4 1 0 0 1 1 1 1 Ribonuclease III domain dsrm PF00035.20 KLO11592.1 - 1.2e-06 28.9 0.0 2.4e-06 28.0 0.0 1.6 1 0 0 1 1 1 1 Double-stranded RNA binding motif Peptidase_M20 PF01546.23 KLO11593.1 - 1.7e-26 92.9 0.0 2.3e-26 92.4 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 KLO11593.1 - 5.2e-10 39.0 0.0 1.1e-09 38.0 0.0 1.6 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.12 KLO11593.1 - 0.0024 17.6 0.0 0.0044 16.7 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.23 KLO11594.1 - 3.9e-27 95.0 0.0 6.2e-27 94.3 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 KLO11594.1 - 4.2e-13 49.0 0.0 8.2e-13 48.0 0.0 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.12 KLO11594.1 - 0.00092 18.9 0.0 0.0019 17.9 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.23 KLO11595.1 - 7.1e-29 100.6 0.1 9.9e-29 100.1 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 KLO11595.1 - 1.1e-11 44.4 0.0 2.2e-11 43.5 0.0 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.12 KLO11595.1 - 0.016 14.9 0.0 0.028 14.1 0.0 1.4 1 0 0 1 1 1 0 Peptidase family M28 DUF3455 PF11937.3 KLO11596.1 - 9.9e-24 84.2 0.0 1.3e-23 83.8 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3455) DUF3455 PF11937.3 KLO11598.1 - 2.6e-23 82.8 0.0 3.4e-23 82.4 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3455) hDGE_amylase PF14701.1 KLO11599.1 - 1.7e-164 547.7 0.0 2.2e-164 547.3 0.0 1.1 1 0 0 1 1 1 1 glucanotransferase domain of human glycogen debranching enzyme GDE_C PF06202.9 KLO11599.1 - 8.1e-114 380.1 0.0 1.2e-113 379.6 0.0 1.2 1 0 0 1 1 1 1 Amylo-alpha-1,6-glucosidase hGDE_central PF14702.1 KLO11599.1 - 1.3e-80 270.3 0.0 1.8e-80 269.8 0.0 1.2 1 0 0 1 1 1 1 central domain of human glycogen debranching enzyme hGDE_N PF14699.1 KLO11599.1 - 5.5e-18 64.5 0.0 1.1e-17 63.6 0.0 1.5 1 0 0 1 1 1 1 N-terminal domain from the human glycogen debranching enzyme Alpha-amylase PF00128.19 KLO11599.1 - 0.0027 17.1 0.0 0.97 8.7 0.0 2.3 2 0 0 2 2 2 2 Alpha amylase, catalytic domain PAT1 PF09770.4 KLO11600.1 - 8e-144 480.8 46.0 1.4e-124 417.1 6.3 2.0 1 1 1 2 2 2 2 Topoisomerase II-associated protein PAT1 Cerato-platanin PF07249.7 KLO11602.1 - 3.6e-20 72.1 0.4 4.3e-20 71.8 0.3 1.1 1 0 0 1 1 1 1 Cerato-platanin Y_phosphatase PF00102.22 KLO11602.1 - 0.11 11.7 0.0 0.12 11.6 0.0 1.1 1 0 0 1 1 1 0 Protein-tyrosine phosphatase Transp_cyt_pur PF02133.10 KLO11603.1 - 7.6e-39 133.4 31.9 1.6e-38 132.4 22.1 1.4 1 1 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin TFIID_30kDa PF03540.8 KLO11604.1 - 8.5e-27 92.7 0.1 1.3e-26 92.1 0.1 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID 23-30kDa subunit FoP_duplication PF13865.1 KLO11604.1 - 0.07 13.5 0.2 0.07 13.5 0.1 2.4 2 1 0 2 2 2 0 C-terminal duplication domain of Friend of PRMT1 Bromo_TP PF07524.8 KLO11604.1 - 0.075 12.7 0.1 3.3 7.5 0.0 2.5 2 0 0 2 2 2 0 Bromodomain associated DDHD PF02862.12 KLO11604.1 - 1.5 8.5 7.1 1.9 8.2 4.9 1.4 1 1 0 1 1 1 0 DDHD domain Fungal_trans PF04082.13 KLO11605.1 - 7.6e-20 70.8 0.1 1.3e-19 70.1 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KLO11605.1 - 4.9e-05 23.1 12.3 0.00011 22.0 8.5 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Tropomyosin PF00261.15 KLO11605.1 - 0.0094 15.0 0.5 0.015 14.4 0.3 1.2 1 0 0 1 1 1 1 Tropomyosin FliD_C PF07195.7 KLO11605.1 - 0.01 15.1 0.8 0.016 14.5 0.6 1.2 1 0 0 1 1 1 0 Flagellar hook-associated protein 2 C-terminus Syntaxin-6_N PF09177.6 KLO11605.1 - 0.16 12.4 0.2 25 5.3 0.1 2.5 2 0 0 2 2 2 0 Syntaxin 6, N-terminal RNA_pol_Rpc4 PF05132.9 KLO11606.1 - 3.3e-22 78.8 0.2 1.3e-21 76.9 0.2 1.9 1 1 0 1 1 1 1 RNA polymerase III RPC4 Pribosyltran PF00156.22 KLO11607.1 - 7.3e-09 35.4 0.0 1e-08 34.9 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosyl transferase domain Mito_carr PF00153.22 KLO11608.1 - 5.1e-73 240.8 4.2 1e-24 86.0 0.0 3.0 2 1 1 3 3 3 3 Mitochondrial carrier protein GFO_IDH_MocA PF01408.17 KLO11609.1 - 2.2e-20 73.3 0.0 3.5e-20 72.6 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold OHCU_decarbox PF09349.5 KLO11610.1 - 3.5e-31 108.6 0.0 4.2e-31 108.3 0.0 1.1 1 0 0 1 1 1 1 OHCU decarboxylase Med4 PF10018.4 KLO11611.1 - 6.8e-23 81.0 0.6 1.1e-22 80.4 0.3 1.4 1 1 0 1 1 1 1 Vitamin-D-receptor interacting Mediator subunit 4 CENP-F_leu_zip PF10473.4 KLO11611.1 - 0.034 13.9 3.8 0.049 13.4 2.7 1.2 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Mito_fiss_reg PF05308.6 KLO11611.1 - 0.31 10.3 6.1 0.84 8.9 0.1 2.2 2 0 0 2 2 2 0 Mitochondrial fission regulator SAGA-Tad1 PF12767.2 KLO11612.1 - 2.2e-33 115.9 0.0 6e-33 114.5 0.0 1.6 1 1 0 1 1 1 1 Transcriptional regulator of RNA polII, SAGA, subunit Kinesin PF00225.18 KLO11613.1 - 6.9e-104 347.1 4.7 1.1e-103 346.4 3.3 1.3 1 0 0 1 1 1 1 Kinesin motor domain Reo_sigmaC PF04582.7 KLO11613.1 - 8.5e-05 21.8 6.6 8.5e-05 21.8 4.5 2.8 3 1 0 3 3 3 1 Reovirus sigma C capsid protein Frigida PF07899.6 KLO11613.1 - 0.0046 15.7 7.6 0.0081 14.9 3.8 2.2 2 0 0 2 2 2 1 Frigida-like protein Filament PF00038.16 KLO11613.1 - 0.01 15.3 21.9 0.012 15.1 1.9 2.4 1 1 1 2 2 2 1 Intermediate filament protein KH_3 PF13014.1 KLO11613.1 - 0.021 14.4 0.1 0.063 12.9 0.1 1.8 1 0 0 1 1 1 0 KH domain DUF4201 PF13870.1 KLO11613.1 - 0.035 13.5 22.5 0.012 15.0 12.0 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4201) Tropomyosin_1 PF12718.2 KLO11613.1 - 0.041 13.7 0.4 0.041 13.7 0.3 3.3 3 0 0 3 3 3 0 Tropomyosin like DUF972 PF06156.8 KLO11613.1 - 0.054 13.8 21.0 0.73 10.2 1.4 4.9 4 1 1 5 5 4 0 Protein of unknown function (DUF972) KH_1 PF00013.24 KLO11613.1 - 0.13 11.9 0.1 0.34 10.5 0.0 1.7 1 0 0 1 1 1 0 KH domain CENP-F_leu_zip PF10473.4 KLO11613.1 - 0.13 12.0 29.1 0.093 12.5 10.8 3.8 2 1 1 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF1664 PF07889.7 KLO11613.1 - 0.32 10.8 13.8 0.35 10.6 1.6 3.5 3 1 1 4 4 4 0 Protein of unknown function (DUF1664) WEMBL PF05701.6 KLO11613.1 - 0.47 8.8 27.1 0.75 8.1 18.8 1.3 1 0 0 1 1 1 0 Weak chloroplast movement under blue light TPR_MLP1_2 PF07926.7 KLO11613.1 - 1.3 8.8 23.1 0.6 9.8 9.7 3.0 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein KxDL PF10241.4 KLO11613.1 - 2.9 7.8 10.6 7.3 6.5 0.4 3.3 1 1 2 3 3 3 0 Uncharacterized conserved protein DUF4407 PF14362.1 KLO11613.1 - 3.3 6.5 11.5 7.1 5.4 8.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Spc7 PF08317.6 KLO11613.1 - 3.5 6.1 20.3 2.4 6.7 9.8 2.5 1 1 1 2 2 2 0 Spc7 kinetochore protein APG6 PF04111.7 KLO11613.1 - 6.1 5.7 23.0 3.7 6.4 2.2 3.2 2 1 1 3 3 3 0 Autophagy protein Apg6 ADIP PF11559.3 KLO11613.1 - 9.5 6.1 32.2 0.74 9.7 9.9 3.4 3 1 1 4 4 2 0 Afadin- and alpha -actinin-Binding Mod_r PF07200.8 KLO11613.1 - 9.5 6.1 25.3 1.2 9.0 5.2 3.1 2 1 1 3 3 3 0 Modifier of rudimentary (Mod(r)) protein FlaC_arch PF05377.6 KLO11613.1 - 9.9 6.1 7.1 15 5.5 0.3 4.0 2 2 1 3 3 3 0 Flagella accessory protein C (FlaC) DPBB_1 PF03330.13 KLO11614.1 - 9.9e-05 22.2 1.0 0.00025 21.0 0.4 1.8 1 1 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Aldo_ket_red PF00248.16 KLO11615.1 - 5.4e-62 209.1 0.0 6.9e-62 208.8 0.0 1.2 1 0 0 1 1 1 1 Aldo/keto reductase family Aldo_ket_red PF00248.16 KLO11616.1 - 4.5e-59 199.6 0.0 5.1e-59 199.4 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family zf-DHHC PF01529.15 KLO11618.1 - 6.9e-19 67.8 3.3 6.9e-19 67.8 2.3 2.3 2 1 0 2 2 2 1 DHHC palmitoyltransferase Ribosomal_L37e PF01907.14 KLO11619.1 - 2.4e-26 91.2 12.5 4.4e-26 90.4 8.7 1.4 1 0 0 1 1 1 1 Ribosomal protein L37e DZR PF12773.2 KLO11619.1 - 0.0023 17.7 1.7 0.0037 17.0 1.2 1.3 1 0 0 1 1 1 1 Double zinc ribbon SelR PF01641.13 KLO11619.1 - 0.0035 17.0 0.5 0.004 16.8 0.3 1.2 1 0 0 1 1 1 1 SelR domain HypA PF01155.14 KLO11619.1 - 0.027 14.1 0.7 0.038 13.6 0.5 1.2 1 0 0 1 1 1 0 Hydrogenase expression/synthesis hypA family Ribosomal_S14 PF00253.16 KLO11619.1 - 0.05 12.9 1.0 0.05 12.9 0.7 2.6 1 1 1 2 2 2 0 Ribosomal protein S14p/S29e GFA PF04828.9 KLO11619.1 - 0.14 12.1 4.4 1.3 9.0 0.6 2.2 1 1 1 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme zf-ribbon_3 PF13248.1 KLO11619.1 - 0.69 9.1 3.0 2.6 7.3 2.2 1.8 1 1 1 2 2 2 0 zinc-ribbon domain zf-C3HC4_2 PF13923.1 KLO11619.1 - 4.3 7.4 6.2 7 6.7 4.3 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DAP3 PF10236.4 KLO11620.1 - 5.2e-63 212.8 0.0 6.8e-63 212.4 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal death-associated protein 3 AAA_16 PF13191.1 KLO11620.1 - 1.3e-06 28.5 0.1 2.8e-06 27.4 0.1 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_25 PF13481.1 KLO11620.1 - 7.2e-05 22.2 0.0 0.00013 21.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain Arch_ATPase PF01637.13 KLO11620.1 - 0.0071 16.0 0.0 0.039 13.6 0.0 2.1 2 1 0 2 2 2 1 Archaeal ATPase AAA_22 PF13401.1 KLO11620.1 - 0.0093 16.1 0.0 0.024 14.7 0.0 1.6 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.12 KLO11620.1 - 0.0099 15.3 0.0 0.018 14.4 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_19 PF13245.1 KLO11620.1 - 0.012 15.3 0.0 0.026 14.2 0.0 1.5 1 0 0 1 1 1 0 Part of AAA domain AAA_28 PF13521.1 KLO11620.1 - 0.045 13.7 0.0 0.079 12.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.1 KLO11620.1 - 0.095 12.5 0.0 0.18 11.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain G-alpha PF00503.15 KLO11620.1 - 0.11 11.1 0.0 0.11 11.1 0.0 1.1 1 0 0 1 1 1 0 G-protein alpha subunit ResIII PF04851.10 KLO11620.1 - 0.13 12.0 0.0 0.2 11.4 0.0 1.3 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit MIP-T3 PF10243.4 KLO11621.1 - 0.11 10.9 23.5 0.15 10.5 0.8 2.1 2 0 0 2 2 2 0 Microtubule-binding protein MIP-T3 TP53IP5 PF15331.1 KLO11621.1 - 0.49 10.2 8.9 14 5.4 5.5 2.5 2 0 0 2 2 2 0 Cellular tumour antigen p53-inducible 5 RNA_pol_Rpc4 PF05132.9 KLO11621.1 - 1.3 9.0 5.3 3.2 7.7 3.6 1.6 1 0 0 1 1 1 0 RNA polymerase III RPC4 YfmQ PF10787.4 KLO11627.1 - 0.005 16.1 0.0 0.0076 15.6 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised protein from bacillus cereus group F-box-like PF12937.2 KLO11628.1 - 3.6e-07 29.7 4.9 4.2e-07 29.5 1.1 2.9 2 1 0 2 2 2 1 F-box-like F-box PF00646.28 KLO11628.1 - 0.015 14.9 2.5 0.13 11.9 0.5 2.9 2 0 0 2 2 2 0 F-box domain F-box-like PF12937.2 KLO11629.1 - 0.00083 19.0 0.6 0.00083 19.0 0.4 3.0 2 1 0 2 2 2 1 F-box-like F-box-like PF12937.2 KLO11630.1 - 0.00028 20.5 0.9 0.0011 18.6 0.1 2.3 2 1 0 2 2 2 1 F-box-like Glyco_hydro_cc PF11790.3 KLO11631.1 - 2.6e-64 216.8 7.8 4.4e-64 216.1 5.4 1.3 1 1 0 1 1 1 1 Glycosyl hydrolase catalytic core RIO1 PF01163.17 KLO11636.1 - 2.6e-05 23.6 0.0 7.4e-05 22.1 0.0 1.7 2 0 0 2 2 2 1 RIO1 family Pkinase PF00069.20 KLO11636.1 - 4.5e-05 22.7 0.0 7.6e-05 21.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.9 KLO11636.1 - 0.00055 19.0 0.0 0.00095 18.2 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KLO11636.1 - 0.0021 17.8 0.1 0.0049 16.6 0.1 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family WaaY PF06176.6 KLO11636.1 - 0.0026 17.0 0.0 0.0043 16.2 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide core biosynthesis protein (WaaY) Pkinase_Tyr PF07714.12 KLO11636.1 - 0.042 12.9 0.0 0.18 10.8 0.0 1.9 1 1 0 1 1 1 0 Protein tyrosine kinase PseudoU_synth_2 PF00849.17 KLO11638.1 - 2.8e-27 95.5 0.0 3.9e-27 95.1 0.0 1.2 1 0 0 1 1 1 1 RNA pseudouridylate synthase F-box-like PF12937.2 KLO11639.1 - 2.8e-07 30.1 0.1 1.2e-06 28.1 0.1 2.1 1 1 0 1 1 1 1 F-box-like F-box PF00646.28 KLO11639.1 - 0.012 15.2 0.7 6.8 6.4 0.0 3.1 3 0 0 3 3 3 0 F-box domain F-box-like PF12937.2 KLO11640.1 - 1.4e-05 24.7 0.0 5.7e-05 22.7 0.1 2.1 2 0 0 2 2 2 1 F-box-like F-box-like PF12937.2 KLO11641.1 - 4.2e-08 32.7 0.0 1.2e-07 31.2 0.0 1.9 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KLO11641.1 - 0.0092 15.6 0.5 0.25 11.0 0.3 2.8 1 1 0 1 1 1 1 F-box domain XPG_I PF00867.13 KLO11642.1 - 5.1e-17 61.7 0.0 1.3e-16 60.4 0.0 1.7 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.12 KLO11642.1 - 2.3e-05 24.5 0.0 0.0001 22.5 0.0 2.1 1 1 0 1 1 1 1 XPG N-terminal domain Prok-E2_E PF14462.1 KLO11642.1 - 0.074 12.6 0.0 0.17 11.5 0.0 1.5 1 0 0 1 1 1 0 Prokaryotic E2 family E F-box PF00646.28 KLO11643.1 - 0.00012 21.6 0.6 0.00012 21.6 0.4 3.3 4 0 0 4 4 4 1 F-box domain F-box-like PF12937.2 KLO11643.1 - 0.013 15.2 0.5 0.049 13.3 0.1 2.2 2 0 0 2 2 2 0 F-box-like F-box-like PF12937.2 KLO11644.1 - 0.069 12.8 1.3 0.11 12.1 0.1 2.1 2 0 0 2 2 2 0 F-box-like zf-C2H2 PF00096.21 KLO11645.1 - 0.54 10.7 1.9 1.8 9.0 0.7 2.4 2 1 0 2 2 2 0 Zinc finger, C2H2 type F-box-like PF12937.2 KLO11646.1 - 0.0013 18.4 0.1 0.0018 17.9 0.1 1.3 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KLO11646.1 - 0.0033 17.0 0.0 0.0058 16.2 0.0 1.4 1 0 0 1 1 1 1 F-box domain SET PF00856.23 KLO11650.1 - 0.00017 21.9 0.0 0.00099 19.4 0.0 2.0 1 1 0 1 1 1 1 SET domain Exo70 PF03081.10 KLO11650.1 - 0.033 12.9 0.0 0.048 12.4 0.0 1.2 1 0 0 1 1 1 0 Exo70 exocyst complex subunit zf-CCHC PF00098.18 KLO11651.1 - 0.56 10.2 0.3 0.56 10.2 0.2 2.6 4 0 0 4 4 4 0 Zinc knuckle Zn_Tnp_IS91 PF14319.1 KLO11651.1 - 1.2 8.6 9.1 2.3 7.7 5.5 2.2 1 1 0 1 1 1 0 Transposase zinc-binding domain IBR PF01485.16 KLO11651.1 - 5.1 7.0 9.2 26 4.7 6.4 2.2 1 1 0 1 1 1 0 IBR domain Abhydrolase_5 PF12695.2 KLO11652.1 - 6.2e-22 77.9 0.0 8.9e-22 77.4 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KLO11652.1 - 1.8e-18 67.2 0.0 6.2e-17 62.2 0.0 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KLO11652.1 - 9.3e-09 35.1 0.0 3.5e-07 30.0 0.0 2.0 1 1 1 2 2 2 1 alpha/beta hydrolase fold BAAT_C PF08840.6 KLO11652.1 - 1e-05 25.3 0.0 0.0011 18.7 0.0 2.3 2 0 0 2 2 2 1 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_2 PF02230.11 KLO11652.1 - 4.3e-05 23.0 0.0 0.12 11.8 0.0 3.1 2 1 1 3 3 3 2 Phospholipase/Carboxylesterase DLH PF01738.13 KLO11652.1 - 0.00025 20.3 0.0 0.11 11.8 0.0 2.4 2 0 0 2 2 2 2 Dienelactone hydrolase family AXE1 PF05448.7 KLO11652.1 - 0.00027 19.5 0.1 0.0095 14.4 0.0 2.2 1 1 1 2 2 2 1 Acetyl xylan esterase (AXE1) Peptidase_S9 PF00326.16 KLO11652.1 - 0.0062 15.7 0.0 0.026 13.7 0.0 1.9 1 1 1 2 2 2 1 Prolyl oligopeptidase family DUF818 PF05677.7 KLO11652.1 - 0.0095 14.6 0.0 0.014 14.1 0.0 1.1 1 0 0 1 1 1 1 Chlamydia CHLPS protein (DUF818) DUF2305 PF10230.4 KLO11652.1 - 0.013 14.9 0.0 0.054 12.9 0.0 1.8 2 0 0 2 2 2 0 Uncharacterised conserved protein (DUF2305) Hydrolase_4 PF12146.3 KLO11652.1 - 0.087 12.6 0.0 0.16 11.8 0.0 1.4 1 0 0 1 1 1 0 Putative lysophospholipase HNH_2 PF13391.1 KLO11654.1 - 3.6e-08 33.0 0.2 1.3e-07 31.3 0.2 1.8 2 0 0 2 2 2 1 HNH endonuclease Sugar_tr PF00083.19 KLO11655.1 - 6.7e-76 255.6 18.9 8.8e-76 255.2 13.1 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KLO11655.1 - 7.6e-32 110.3 15.6 7.6e-32 110.3 10.8 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.8 KLO11655.1 - 0.0012 17.1 0.7 0.0017 16.6 0.5 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_3 PF05977.8 KLO11655.1 - 0.0074 14.4 5.2 0.014 13.5 0.2 2.5 1 1 1 2 2 2 1 Transmembrane secretion effector MFS_1_like PF12832.2 KLO11655.1 - 0.31 10.8 0.0 0.31 10.8 0.0 3.1 3 0 0 3 3 3 0 MFS_1 like family DUF21 PF01595.15 KLO11657.1 - 2.2 7.5 10.0 3.7 6.7 6.9 1.4 1 0 0 1 1 1 0 Domain of unknown function DUF21 GMC_oxred_N PF00732.14 KLO11658.1 - 8.8e-19 67.7 0.0 2.6e-18 66.2 0.0 1.8 1 1 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 KLO11658.1 - 3e-18 66.4 0.1 6.5e-18 65.4 0.1 1.6 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 KLO11658.1 - 3.3e-08 32.8 0.2 2.2e-05 23.5 0.3 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KLO11658.1 - 1.3e-06 28.3 0.1 3.4e-06 26.9 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 KLO11658.1 - 2.5e-05 23.5 0.0 0.0015 17.6 0.0 2.3 2 0 0 2 2 2 1 Thi4 family FAD_binding_2 PF00890.19 KLO11658.1 - 3.8e-05 22.7 0.1 9.4e-05 21.4 0.2 1.5 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.9 KLO11658.1 - 0.00015 20.3 0.0 0.00025 19.6 0.0 1.3 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox_2 PF07992.9 KLO11658.1 - 0.00018 21.4 0.0 0.00034 20.5 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 KLO11658.1 - 0.00025 20.2 0.5 0.00042 19.4 0.3 1.2 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.2 KLO11658.1 - 0.0011 18.1 0.2 0.0085 15.2 0.1 2.0 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 KLO11658.1 - 0.0024 17.9 0.0 0.0084 16.1 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 KLO11658.1 - 0.2 10.4 0.1 0.31 9.8 0.1 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A Pyr_redox PF00070.22 KLO11658.1 - 0.2 12.0 0.1 0.65 10.4 0.0 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 KLO11658.1 - 0.23 10.3 0.1 0.32 9.8 0.1 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein F-box-like PF12937.2 KLO11659.1 - 6.3e-06 25.8 0.3 2.2e-05 24.1 0.2 2.0 1 1 0 1 1 1 1 F-box-like WSC PF01822.14 KLO11660.1 - 2.3e-61 203.6 55.2 1.7e-17 63.1 6.1 4.4 4 0 0 4 4 4 4 WSC domain Glyoxal_oxid_N PF07250.6 KLO11660.1 - 1.1e-28 99.9 0.0 5.8e-27 94.3 0.0 3.0 2 1 0 3 3 3 1 Glyoxal oxidase N-terminus DUF1929 PF09118.6 KLO11660.1 - 1.6e-20 73.0 0.1 3.4e-20 71.9 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1929) Kelch_2 PF07646.10 KLO11660.1 - 0.094 12.5 2.5 0.74 9.6 0.0 3.7 4 0 0 4 4 4 0 Kelch motif F-box-like PF12937.2 KLO11661.1 - 1.7e-07 30.8 0.1 8.2e-07 28.6 0.1 2.2 1 1 0 1 1 1 1 F-box-like F-box PF00646.28 KLO11661.1 - 0.01 15.4 0.8 4.5 7.0 0.1 2.9 2 0 0 2 2 2 0 F-box domain PseudoU_synth_2 PF00849.17 KLO11662.1 - 3.3e-26 92.0 0.0 5e-26 91.4 0.0 1.3 1 0 0 1 1 1 1 RNA pseudouridylate synthase F-box-like PF12937.2 KLO11663.1 - 1.3e-07 31.2 0.0 1.3e-07 31.2 0.0 2.7 3 1 0 3 3 3 1 F-box-like F-box PF00646.28 KLO11663.1 - 0.11 12.1 3.9 0.48 10.1 0.7 3.1 2 1 0 2 2 2 0 F-box domain Rap_GAP PF02145.10 KLO11664.1 - 5e-43 146.6 0.0 8.5e-43 145.9 0.0 1.3 1 0 0 1 1 1 1 Rap/ran-GAP Tuberin PF03542.11 KLO11664.1 - 4.5e-31 108.2 0.0 9.6e-31 107.1 0.0 1.5 1 0 0 1 1 1 1 Tuberin DUF3384 PF11864.3 KLO11664.1 - 9.8e-07 27.5 0.0 2e-05 23.2 0.0 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF3384) DUF307 PF03733.8 KLO11664.1 - 0.18 12.2 0.6 0.5 10.8 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF307) 4HBT PF03061.17 KLO11665.1 - 1.4e-06 28.2 0.1 0.0044 17.1 0.0 2.4 2 0 0 2 2 2 2 Thioesterase superfamily zf-MYND PF01753.13 KLO11666.1 - 7.1e-10 38.5 14.8 1.3e-09 37.7 10.2 1.4 1 0 0 1 1 1 1 MYND finger zf-MYND PF01753.13 KLO11667.1 - 0.0058 16.4 4.4 0.012 15.4 3.0 1.5 1 0 0 1 1 1 1 MYND finger zf-MYND PF01753.13 KLO11668.1 - 9.6e-10 38.1 10.2 2.8e-09 36.6 7.1 1.9 1 0 0 1 1 1 1 MYND finger zf-Mss51 PF13824.1 KLO11668.1 - 0.061 13.1 4.5 0.17 11.7 3.1 1.8 1 0 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 zf-MYND PF01753.13 KLO11669.1 - 4.6e-11 42.4 12.0 4.6e-11 42.4 8.3 2.3 2 0 0 2 2 2 1 MYND finger DEDD_Tnp_IS110 PF01548.12 KLO11669.1 - 0.14 11.8 0.0 0.35 10.5 0.0 1.6 1 0 0 1 1 1 0 Transposase zf-Mss51 PF13824.1 KLO11669.1 - 0.18 11.7 4.8 0.58 10.0 2.9 2.2 2 0 0 2 2 2 0 Zinc-finger of mitochondrial splicing suppressor 51 Amino_oxidase PF01593.19 KLO11670.1 - 1.5e-63 215.5 0.9 2.7e-51 175.0 0.0 2.4 2 1 0 2 2 2 2 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 KLO11670.1 - 2.4e-08 33.8 0.2 5.7e-08 32.6 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 KLO11670.1 - 1.8e-05 23.8 1.0 0.00057 18.8 0.2 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 KLO11670.1 - 4.9e-05 23.4 0.4 0.017 15.2 0.2 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 KLO11670.1 - 0.00036 20.8 0.8 0.05 14.0 0.1 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 KLO11670.1 - 0.0034 16.4 0.7 0.0058 15.7 0.5 1.3 1 0 0 1 1 1 1 FAD binding domain FAD_binding_2 PF00890.19 KLO11670.1 - 0.0097 14.7 0.3 0.014 14.2 0.2 1.2 1 0 0 1 1 1 1 FAD binding domain NAD_binding_9 PF13454.1 KLO11670.1 - 0.011 15.4 0.9 0.79 9.4 0.0 2.3 2 0 0 2 2 2 0 FAD-NAD(P)-binding FAD_oxidored PF12831.2 KLO11670.1 - 0.018 14.1 0.4 0.049 12.7 0.4 1.6 2 0 0 2 2 2 0 FAD dependent oxidoreductase HI0933_like PF03486.9 KLO11670.1 - 0.025 13.0 0.4 0.52 8.7 0.1 2.1 2 0 0 2 2 2 0 HI0933-like protein Shikimate_DH PF01488.15 KLO11670.1 - 0.12 12.4 0.1 0.22 11.5 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase AAA_11 PF13086.1 KLO11671.1 - 2.5e-17 63.2 0.0 4e-10 39.6 0.0 2.2 1 1 1 2 2 2 2 AAA domain AAA_19 PF13245.1 KLO11671.1 - 3.9e-10 39.3 0.0 8.2e-10 38.2 0.0 1.5 1 0 0 1 1 1 1 Part of AAA domain AAA_30 PF13604.1 KLO11671.1 - 1e-09 38.2 0.0 5.1e-09 35.9 0.0 2.2 2 1 0 2 2 2 1 AAA domain AAA_12 PF13087.1 KLO11671.1 - 1.4e-05 24.6 0.0 2.5e-05 23.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 KLO11671.1 - 1.9e-05 24.7 0.0 3.9e-05 23.7 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 KLO11671.1 - 0.0013 18.8 0.0 0.0077 16.3 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA PF00004.24 KLO11671.1 - 0.0018 18.4 0.0 0.0064 16.6 0.0 1.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) DEAD PF00270.24 KLO11671.1 - 0.0029 17.1 0.0 0.019 14.4 0.0 2.1 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_17 PF13207.1 KLO11671.1 - 0.015 16.0 0.1 0.055 14.2 0.1 1.9 1 1 0 1 1 1 0 AAA domain Viral_helicase1 PF01443.13 KLO11671.1 - 0.016 14.7 0.1 0.76 9.2 0.0 2.6 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase Miro PF08477.8 KLO11671.1 - 0.02 15.3 0.0 0.047 14.1 0.0 1.6 1 0 0 1 1 1 0 Miro-like protein PhoH PF02562.11 KLO11671.1 - 0.022 14.0 0.0 0.049 12.8 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein AAA_33 PF13671.1 KLO11671.1 - 0.03 14.1 0.0 0.12 12.2 0.0 2.1 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 KLO11671.1 - 0.035 14.4 0.0 0.14 12.4 0.0 2.0 2 1 0 2 2 1 0 AAA domain DUF2075 PF09848.4 KLO11671.1 - 0.049 12.6 0.0 0.099 11.6 0.0 1.7 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Zeta_toxin PF06414.7 KLO11671.1 - 0.058 12.4 0.1 0.74 8.8 0.0 2.1 2 0 0 2 2 2 0 Zeta toxin T2SE PF00437.15 KLO11671.1 - 0.072 11.9 0.0 0.12 11.2 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein NB-ARC PF00931.17 KLO11671.1 - 0.073 11.9 0.0 0.12 11.2 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain ResIII PF04851.10 KLO11671.1 - 0.093 12.5 0.0 0.18 11.5 0.0 1.5 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit PIF1 PF05970.9 KLO11671.1 - 0.11 11.3 0.0 0.18 10.7 0.0 1.2 1 0 0 1 1 1 0 PIF1-like helicase Helicase_RecD PF05127.9 KLO11671.1 - 0.11 12.0 0.0 0.55 9.8 0.0 2.0 1 1 0 1 1 1 0 Helicase AAA_12 PF13087.1 KLO11672.1 - 2e-20 73.0 0.0 2.2e-20 72.8 0.0 1.0 1 0 0 1 1 1 1 AAA domain UvrD_C_2 PF13538.1 KLO11672.1 - 0.0074 16.4 0.0 0.017 15.2 0.0 1.6 1 1 0 1 1 1 1 UvrD-like helicase C-terminal domain Asp PF00026.18 KLO11674.1 - 4.5e-79 265.9 6.4 5.8e-79 265.6 4.4 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 KLO11674.1 - 0.00017 21.6 0.9 0.00017 21.6 0.6 2.1 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal TAXi_C PF14541.1 KLO11674.1 - 0.00076 19.0 0.4 0.0017 17.9 0.0 1.8 2 0 0 2 2 2 1 Xylanase inhibitor C-terminal DUF1265 PF06887.9 KLO11675.1 - 0.045 13.4 0.3 0.26 10.9 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1265) DUF2164 PF09932.4 KLO11676.1 - 0.024 14.4 0.4 0.083 12.7 0.2 2.0 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2164) Baculo_PEP_C PF04513.7 KLO11676.1 - 0.12 12.2 2.8 0.37 10.6 2.0 1.9 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Peptidase_S64 PF08192.6 KLO11676.1 - 0.22 9.8 2.0 0.46 8.7 1.4 1.5 1 1 0 1 1 1 0 Peptidase family S64 Uteroglobin PF01099.12 KLO11677.1 - 0.0074 16.0 2.5 12 5.7 0.0 3.6 3 0 0 3 3 3 2 Uteroglobin family DUF2951 PF11166.3 KLO11677.1 - 2 8.3 9.6 0.57 10.0 0.5 3.2 3 1 1 4 4 4 0 Protein of unknown function (DUF2951) HPP PF04982.8 KLO11679.1 - 0.061 13.1 2.4 0.12 12.2 1.6 1.4 1 0 0 1 1 1 0 HPP family Pkinase PF00069.20 KLO11690.1 - 4.9e-28 98.0 0.0 5.7e-28 97.7 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KLO11690.1 - 2.9e-21 75.7 0.0 3.6e-21 75.4 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KLO11690.1 - 8.7e-05 21.6 0.0 0.00016 20.7 0.0 1.4 1 1 0 1 1 1 1 Kinase-like RIO1 PF01163.17 KLO11690.1 - 0.0063 15.8 0.0 0.0087 15.4 0.0 1.1 1 0 0 1 1 1 1 RIO1 family APH PF01636.18 KLO11690.1 - 0.011 15.4 0.0 0.013 15.2 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pkinase PF00069.20 KLO11692.1 - 8.3e-42 143.1 0.0 1.2e-41 142.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KLO11692.1 - 1e-35 123.1 0.0 1.4e-35 122.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KLO11692.1 - 1.7e-05 23.9 0.0 2.8e-05 23.2 0.0 1.2 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.17 KLO11692.1 - 0.0053 16.1 0.1 0.018 14.3 0.0 1.8 2 0 0 2 2 2 1 RIO1 family Kdo PF06293.9 KLO11692.1 - 0.062 12.3 0.0 0.31 10.0 0.0 1.9 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family RNase_H PF00075.19 KLO11694.1 - 0.0049 17.1 0.0 0.0089 16.3 0.0 1.5 1 0 0 1 1 1 1 RNase H zf-RVT PF13966.1 KLO11694.1 - 0.066 13.5 0.0 0.27 11.5 0.0 1.8 1 1 0 2 2 2 0 zinc-binding in reverse transcriptase DUF664 PF04978.7 KLO11695.1 - 0.078 13.2 0.3 3 8.0 0.1 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF664) Pkinase PF00069.20 KLO11696.1 - 2.5e-35 121.9 0.0 2.7e-35 121.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KLO11696.1 - 1.4e-30 106.2 0.0 1.6e-30 106.0 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KLO11696.1 - 2.3e-06 26.7 0.0 3.2e-06 26.3 0.0 1.1 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.17 KLO11696.1 - 0.007 15.7 0.0 0.01 15.2 0.0 1.2 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.9 KLO11696.1 - 0.022 13.8 0.0 0.033 13.2 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KLO11696.1 - 0.12 12.0 0.0 0.18 11.5 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pkinase PF00069.20 KLO11698.1 - 3.3e-43 147.7 0.0 4.9e-43 147.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KLO11698.1 - 2.3e-35 121.9 0.0 3.4e-35 121.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KLO11698.1 - 1.3e-05 24.3 0.0 2e-05 23.7 0.0 1.2 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.17 KLO11698.1 - 0.00047 19.5 0.0 0.00085 18.7 0.0 1.3 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.9 KLO11698.1 - 0.0013 17.8 0.0 0.013 14.5 0.0 2.2 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KLO11698.1 - 0.15 11.8 0.0 0.23 11.1 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family CheZ PF04344.8 KLO11701.1 - 0.011 15.4 0.8 0.015 15.0 0.5 1.2 1 0 0 1 1 1 0 Chemotaxis phosphatase, CheZ Filament PF00038.16 KLO11701.1 - 0.036 13.5 2.6 0.042 13.3 1.8 1.1 1 0 0 1 1 1 0 Intermediate filament protein APG6 PF04111.7 KLO11701.1 - 0.061 12.3 2.5 0.07 12.1 1.7 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 GDE_C PF06202.9 KLO11701.1 - 0.066 11.9 0.5 0.082 11.6 0.3 1.1 1 0 0 1 1 1 0 Amylo-alpha-1,6-glucosidase Nsp1_C PF05064.8 KLO11701.1 - 0.078 12.6 1.5 0.13 11.8 0.9 1.4 1 1 0 1 1 1 0 Nsp1-like C-terminal region Tropomyosin_1 PF12718.2 KLO11701.1 - 0.3 10.9 4.8 1.6 8.5 0.6 2.1 1 1 1 2 2 2 0 Tropomyosin like TMF_DNA_bd PF12329.3 KLO11701.1 - 0.44 10.3 3.7 0.42 10.4 0.1 2.2 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding Presenilin PF01080.12 KLO11701.1 - 0.68 8.6 2.2 0.79 8.4 1.5 1.1 1 0 0 1 1 1 0 Presenilin TPR_MLP1_2 PF07926.7 KLO11701.1 - 0.77 9.5 5.4 1.8 8.2 3.8 1.7 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein MCPsignal PF00015.16 KLO11702.1 - 0.00019 21.0 2.2 0.00019 21.0 1.6 2.0 2 1 0 2 2 2 1 Methyl-accepting chemotaxis protein (MCP) signalling domain ISG65-75 PF11727.3 KLO11702.1 - 0.0019 17.2 2.3 0.0019 17.2 1.6 2.0 2 0 0 2 2 2 1 Invariant surface glycoprotein Reo_sigmaC PF04582.7 KLO11702.1 - 0.0065 15.6 1.5 0.009 15.2 0.6 1.6 2 0 0 2 2 2 1 Reovirus sigma C capsid protein HAUS-augmin3 PF14932.1 KLO11702.1 - 0.0072 15.5 5.4 0.0072 15.5 3.8 2.1 2 1 0 2 2 2 1 HAUS augmin-like complex subunit 3 COG2 PF06148.6 KLO11702.1 - 0.018 14.8 4.7 0.018 14.8 3.3 2.5 2 1 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 NPV_P10 PF05531.7 KLO11702.1 - 0.021 15.0 1.3 0.021 15.0 0.9 2.6 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein SNARE PF05739.14 KLO11702.1 - 0.068 12.8 0.6 0.068 12.8 0.4 3.5 3 1 1 4 4 4 0 SNARE domain DUF148 PF02520.12 KLO11702.1 - 0.08 12.7 4.5 0.44 10.3 0.3 2.5 1 1 1 2 2 2 0 Domain of unknown function DUF148 Apolipoprotein PF01442.13 KLO11702.1 - 0.094 12.2 16.6 0.16 11.4 5.7 2.5 2 1 0 2 2 2 0 Apolipoprotein A1/A4/E domain Prominin PF05478.6 KLO11702.1 - 0.12 9.9 0.5 0.19 9.2 0.4 1.3 1 0 0 1 1 1 0 Prominin Laminin_II PF06009.7 KLO11702.1 - 0.12 12.0 12.5 0.64 9.7 3.3 2.3 2 0 0 2 2 2 0 Laminin Domain II Spc7 PF08317.6 KLO11702.1 - 0.17 10.4 11.7 0.032 12.8 3.6 2.2 2 0 0 2 2 2 0 Spc7 kinetochore protein Baculo_PEP_C PF04513.7 KLO11702.1 - 0.22 11.3 3.5 0.18 11.6 1.5 1.6 2 0 0 2 2 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Lectin_N PF03954.9 KLO11702.1 - 0.23 10.8 2.7 0.28 10.5 1.1 1.8 2 0 0 2 2 2 0 Hepatic lectin, N-terminal domain DUF948 PF06103.6 KLO11702.1 - 0.29 11.0 4.2 1.8 8.4 0.7 2.8 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) DUF1664 PF07889.7 KLO11702.1 - 0.39 10.5 6.9 0.1 12.3 0.8 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) DUF3450 PF11932.3 KLO11702.1 - 0.69 9.1 9.0 0.19 10.9 3.2 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF3450) IncA PF04156.9 KLO11702.1 - 0.7 9.4 20.1 0.034 13.7 8.3 2.1 1 1 0 2 2 2 0 IncA protein Atg14 PF10186.4 KLO11702.1 - 0.77 8.6 18.1 0.082 11.8 5.8 2.0 1 1 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 Spectrin PF00435.16 KLO11702.1 - 0.82 9.9 13.0 3.4 8.0 5.1 2.7 2 1 0 2 2 2 0 Spectrin repeat YlqD PF11068.3 KLO11702.1 - 0.94 9.5 10.1 1.6 8.8 3.1 2.8 2 1 0 3 3 3 0 YlqD protein Fib_alpha PF08702.5 KLO11702.1 - 1.1 9.3 7.2 0.67 10.0 2.6 2.1 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family Cluap1 PF10234.4 KLO11702.1 - 1.2 8.2 12.2 5 6.2 7.8 2.3 1 1 0 1 1 1 0 Clusterin-associated protein-1 HisKA_3 PF07730.8 KLO11702.1 - 1.6 9.1 14.1 0.94 9.8 1.0 3.5 2 2 1 3 3 3 0 Histidine kinase GAS PF13851.1 KLO11702.1 - 1.8 7.7 18.0 0.044 12.9 5.8 2.7 2 2 0 2 2 2 0 Growth-arrest specific micro-tubule binding Cob_adeno_trans PF01923.13 KLO11702.1 - 1.8 8.3 7.2 0.53 10.0 1.8 2.0 2 0 0 2 2 2 0 Cobalamin adenosyltransferase LPP PF04728.8 KLO11702.1 - 2.1 8.2 5.0 13 5.6 0.9 2.8 2 1 1 3 3 3 0 Lipoprotein leucine-zipper APG6 PF04111.7 KLO11702.1 - 2.3 7.1 17.3 0.05 12.6 5.6 2.0 2 0 0 2 2 2 0 Autophagy protein Apg6 Mod_r PF07200.8 KLO11702.1 - 2.9 7.7 14.5 1.6 8.6 5.1 2.5 2 1 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein FlaC_arch PF05377.6 KLO11702.1 - 3.1 7.7 6.4 2.1 8.3 0.4 3.2 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) Mnd1 PF03962.10 KLO11702.1 - 3.3 7.3 15.5 0.12 12.0 4.0 2.4 2 0 0 2 2 2 0 Mnd1 family Adeno_PIX PF03955.9 KLO11702.1 - 4 8.0 11.5 1.2 9.7 3.8 2.7 2 2 1 3 3 3 0 Adenovirus hexon-associated protein (IX) Syntaxin-6_N PF09177.6 KLO11702.1 - 4.5 7.7 8.7 2.3 8.6 2.5 2.5 2 1 0 2 2 2 0 Syntaxin 6, N-terminal Prefoldin PF02996.12 KLO11702.1 - 5.2 6.7 10.8 8 6.1 0.1 3.5 2 1 1 3 3 3 0 Prefoldin subunit UPF0242 PF06785.6 KLO11702.1 - 5.4 5.5 10.1 2.6 6.6 0.9 2.4 2 1 0 2 2 2 0 Uncharacterised protein family (UPF0242) CENP-F_leu_zip PF10473.4 KLO11702.1 - 9.9 6.0 23.5 0.33 10.8 9.2 2.7 2 2 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF4407 PF14362.1 KLO11702.1 - 9.9 5.0 12.0 1.3 7.8 2.3 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) ATG16 PF08614.6 KLO11703.1 - 0.034 13.9 9.6 0.055 13.2 6.6 1.3 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) IncA PF04156.9 KLO11703.1 - 0.39 10.3 7.3 0.067 12.7 1.2 2.0 2 0 0 2 2 2 0 IncA protein Atg14 PF10186.4 KLO11703.1 - 1.7 7.4 9.8 1.9 7.3 6.8 1.3 1 1 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DUF327 PF03885.8 KLO11704.1 - 0.1 12.4 0.3 0.1 12.4 0.2 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF327) MetJ PF01340.15 KLO11704.1 - 0.1 12.3 1.1 1.5 8.6 0.0 2.3 1 1 1 2 2 2 0 Met Apo-repressor, MetJ Adeno_PIX PF03955.9 KLO11704.1 - 1.2 9.7 3.9 2 8.9 0.1 2.2 2 0 0 2 2 2 0 Adenovirus hexon-associated protein (IX) DUF506 PF04720.7 KLO11704.1 - 3.1 7.3 12.3 0.034 13.7 0.9 2.3 1 1 0 2 2 2 0 Protein of unknown function (DUF506) DUF1014 PF06244.7 KLO11705.1 - 4.3e-25 88.2 9.9 4.5e-25 88.2 3.8 2.6 2 1 0 2 2 2 1 Protein of unknown function (DUF1014) Matrilin_ccoil PF10393.4 KLO11705.1 - 0.14 11.5 1.3 0.23 10.8 0.9 1.3 1 0 0 1 1 1 0 Trimeric coiled-coil oligomerisation domain of matrilin DUF2852 PF11014.3 KLO11705.1 - 0.16 11.9 5.2 1.9 8.4 1.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2852) EspB PF05802.6 KLO11705.1 - 1.2 7.9 3.8 0.37 9.6 0.9 1.4 2 0 0 2 2 2 0 Enterobacterial EspB protein Fasciclin PF02469.17 KLO11710.1 - 1.3e-08 34.9 0.0 2.2e-08 34.1 0.0 1.3 1 1 0 1 1 1 1 Fasciclin domain Adaptin_N PF01602.15 KLO11711.1 - 9.7e-92 307.9 3.4 1.6e-91 307.2 2.3 1.3 1 0 0 1 1 1 1 Adaptin N terminal region Coatomer_b_Cpla PF14806.1 KLO11711.1 - 5.5e-67 223.4 0.1 1.4e-66 222.1 0.0 1.8 1 0 0 1 1 1 1 Coatomer beta subunit appendage platform Coatamer_beta_C PF07718.7 KLO11711.1 - 6.5e-58 194.3 0.0 1.8e-57 192.9 0.0 1.8 1 0 0 1 1 1 1 Coatomer beta C-terminal region HEAT_2 PF13646.1 KLO11711.1 - 4.1e-10 39.8 0.9 0.008 16.4 0.0 4.3 3 1 2 5 5 5 3 HEAT repeats Cnd1 PF12717.2 KLO11711.1 - 3.9e-07 30.0 2.2 0.086 12.6 0.0 4.0 2 2 1 3 3 3 3 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.17 KLO11711.1 - 2.1e-05 24.1 0.0 0.086 12.9 0.0 4.6 4 0 0 4 4 4 1 HEAT repeat HEAT_EZ PF13513.1 KLO11711.1 - 0.00028 21.2 0.1 1.3 9.6 0.1 3.8 2 1 1 3 3 3 2 HEAT-like repeat ParcG PF10274.4 KLO11711.1 - 0.15 11.9 2.1 4.2 7.2 0.0 2.9 3 0 0 3 3 3 0 Parkin co-regulated protein Pkinase PF00069.20 KLO11712.1 - 2.5e-34 118.5 0.0 3e-34 118.3 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KLO11712.1 - 1.4e-29 102.9 0.1 1.7e-29 102.7 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KLO11712.1 - 0.0001 21.3 0.0 0.00012 21.1 0.0 1.2 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.17 KLO11712.1 - 0.0087 15.4 0.0 0.011 15.0 0.0 1.2 1 0 0 1 1 1 1 RIO1 family APH PF01636.18 KLO11712.1 - 0.062 13.0 0.0 0.13 11.9 0.0 1.4 1 1 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.9 KLO11712.1 - 0.064 12.3 0.0 0.089 11.8 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Glyco_hydro_7 PF00840.15 KLO11714.1 - 1.1e-210 699.5 21.6 1.6e-210 698.9 15.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 7 CBM_1 PF00734.13 KLO11714.1 - 9.8e-13 47.5 12.2 9.8e-13 47.5 8.5 4.6 5 1 0 5 5 5 1 Fungal cellulose binding domain DUF2367 PF10164.4 KLO11715.1 - 1.9e-05 24.3 4.6 4.5e-05 23.2 3.2 1.8 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2367) CUE PF02845.11 KLO11716.1 - 5.3e-08 32.1 0.0 8.7e-08 31.5 0.0 1.4 1 0 0 1 1 1 1 CUE domain CoA_transf_3 PF02515.12 KLO11716.1 - 0.0029 16.8 0.4 0.0062 15.7 0.2 1.6 1 1 0 1 1 1 1 CoA-transferase family III peroxidase PF00141.18 KLO11717.1 - 3.2e-28 98.7 0.0 5e-28 98.1 0.0 1.3 1 0 0 1 1 1 1 Peroxidase DUF3415 PF11895.3 KLO11717.1 - 7.2e-23 80.2 1.5 1.1e-22 79.7 0.4 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF3415) DUF627 PF04781.7 KLO11717.1 - 0.0076 15.8 0.2 0.012 15.2 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF627) DUF663 PF04950.7 KLO11718.1 - 2.7e-84 282.6 0.0 5.7e-84 281.5 0.0 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF663) AARP2CN PF08142.7 KLO11718.1 - 6.1e-19 67.3 0.0 1.5e-18 66.0 0.0 1.7 1 0 0 1 1 1 1 AARP2CN (NUC121) domain DUF3844 PF12955.2 KLO11719.1 - 3.1e-29 101.1 1.7 4.6e-29 100.5 1.2 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3844) EGF_3 PF12947.2 KLO11719.1 - 5.2 7.1 9.4 8.3 6.4 6.5 1.3 1 0 0 1 1 1 0 EGF domain peroxidase PF00141.18 KLO11720.1 - 3e-31 108.7 0.0 4.7e-31 108.0 0.0 1.3 1 0 0 1 1 1 1 Peroxidase DUF3415 PF11895.3 KLO11720.1 - 3e-25 87.9 2.4 7e-25 86.7 1.7 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3415) DUF1674 PF07896.7 KLO11721.1 - 2.6e-14 53.1 3.4 4.2e-14 52.4 2.3 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1674) Fungal_trans PF04082.13 KLO11722.1 - 1.1e-24 86.6 0.0 5.1e-24 84.5 0.0 1.9 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KLO11722.1 - 2e-08 34.0 12.3 3.8e-08 33.0 8.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Gal4_dimer PF03902.8 KLO11722.1 - 0.0022 17.8 0.0 0.0048 16.7 0.0 1.5 1 0 0 1 1 1 1 Gal4-like dimerisation domain G-alpha PF00503.15 KLO11724.1 - 4.2e-126 420.7 0.2 5e-126 420.5 0.1 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 KLO11724.1 - 3.8e-16 58.8 0.5 5e-11 42.1 0.0 2.6 2 0 0 2 2 2 2 ADP-ribosylation factor family Miro PF08477.8 KLO11724.1 - 0.00048 20.6 0.2 0.42 11.1 0.0 2.9 2 1 0 2 2 2 2 Miro-like protein Gtr1_RagA PF04670.7 KLO11724.1 - 0.00068 18.8 2.1 0.026 13.6 0.0 2.5 3 0 0 3 3 3 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 KLO11724.1 - 0.018 15.0 0.1 0.89 9.5 0.0 2.5 1 1 0 1 1 1 0 50S ribosome-binding GTPase GTP_EFTU PF00009.22 KLO11724.1 - 0.03 13.7 0.0 6.7 6.0 0.0 2.6 3 0 0 3 3 3 0 Elongation factor Tu GTP binding domain AAA_29 PF13555.1 KLO11724.1 - 0.035 13.6 0.0 0.071 12.6 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain zf-CHC2 PF01807.15 KLO11724.1 - 0.1 12.1 0.0 0.4 10.2 0.0 1.9 2 0 0 2 2 2 0 CHC2 zinc finger FtsK_SpoIIIE PF01580.13 KLO11724.1 - 0.13 11.7 0.0 0.28 10.6 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family tRNA-synt_2c PF01411.14 KLO11725.1 - 8.3e-217 720.8 0.0 1.3e-216 720.2 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class II (A) tRNA_SAD PF07973.9 KLO11725.1 - 5e-16 58.3 0.3 1.2e-15 57.1 0.2 1.7 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain DHHA1 PF02272.14 KLO11725.1 - 6.9e-07 28.8 0.3 2.8e-06 26.9 0.2 2.0 1 0 0 1 1 1 1 DHHA1 domain RPW8 PF05659.6 KLO11725.1 - 0.014 14.9 1.1 5.5 6.5 0.0 2.5 2 0 0 2 2 2 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 G-alpha PF00503.15 KLO11726.1 - 1.5e-117 392.5 0.0 2e-117 392.1 0.0 1.1 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 KLO11726.1 - 2.8e-09 36.4 0.0 8.8e-08 31.5 0.0 2.5 2 0 0 2 2 2 1 ADP-ribosylation factor family AAA_29 PF13555.1 KLO11726.1 - 0.062 12.8 0.0 0.18 11.3 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain Ras PF00071.17 KLO11726.1 - 0.1 12.0 0.0 2.3 7.6 0.0 2.3 2 0 0 2 2 2 0 Ras family Myc-LZ PF02344.10 KLO11726.1 - 0.54 9.9 5.6 1.3 8.7 3.9 1.6 1 0 0 1 1 1 0 Myc leucine zipper domain EI24 PF07264.6 KLO11727.1 - 2.8e-07 30.1 2.2 5.5e-07 29.2 1.5 1.5 1 1 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) Glycophorin_A PF01102.13 KLO11727.1 - 0.14 11.9 0.0 0.37 10.5 0.0 1.6 2 0 0 2 2 2 0 Glycophorin A Prenylcys_lyase PF07156.9 KLO11728.1 - 7.8e-47 159.9 0.0 1.1e-46 159.4 0.0 1.1 1 0 0 1 1 1 1 Prenylcysteine lyase NAD_binding_8 PF13450.1 KLO11728.1 - 1e-09 38.2 0.0 2.5e-09 37.0 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.19 KLO11728.1 - 4e-07 29.4 0.0 0.0085 15.2 0.0 2.1 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase DAO PF01266.19 KLO11728.1 - 0.00011 21.2 0.0 0.0004 19.3 0.0 1.8 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 KLO11728.1 - 0.0056 16.4 0.1 0.032 14.0 0.0 2.2 3 0 0 3 3 3 1 FAD-NAD(P)-binding Thi4 PF01946.12 KLO11728.1 - 0.01 14.9 0.2 0.022 13.8 0.1 1.5 1 0 0 1 1 1 0 Thi4 family Pyr_redox_2 PF07992.9 KLO11728.1 - 0.018 14.9 0.0 0.041 13.7 0.0 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase IP_trans PF02121.13 KLO11728.1 - 0.035 13.2 0.1 0.1 11.7 0.0 1.7 2 0 0 2 2 2 0 Phosphatidylinositol transfer protein FAD_binding_3 PF01494.14 KLO11728.1 - 0.036 13.1 0.0 0.061 12.3 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain FAD_oxidored PF12831.2 KLO11728.1 - 0.072 12.1 0.1 3 6.7 0.0 2.1 2 0 0 2 2 2 0 FAD dependent oxidoreductase GIDA PF01134.17 KLO11728.1 - 0.079 11.8 0.4 0.15 10.8 0.3 1.4 1 0 0 1 1 1 0 Glucose inhibited division protein A Pyr_redox_3 PF13738.1 KLO11728.1 - 0.1 12.6 0.1 1.1 9.2 0.0 2.4 2 1 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase zf-CCHC PF00098.18 KLO11729.1 - 1.2e-11 43.9 23.8 0.00061 19.5 0.8 4.4 4 0 0 4 4 4 4 Zinc knuckle zf-CCHC_2 PF13696.1 KLO11729.1 - 1.5e-08 33.9 12.5 0.0031 16.9 0.2 4.0 2 1 2 4 4 4 3 Zinc knuckle zf-CCHC_4 PF14392.1 KLO11729.1 - 0.0001 21.8 20.4 0.046 13.3 0.7 4.4 4 0 0 4 4 4 3 Zinc knuckle zf-CCHC_5 PF14787.1 KLO11729.1 - 0.89 9.0 17.2 0.26 10.7 0.6 3.7 4 0 0 4 4 4 0 GAG-polyprotein viral zinc-finger zf-CCHC_3 PF13917.1 KLO11729.1 - 2.2 8.1 18.7 4.5 7.0 0.3 4.2 3 1 1 4 4 4 0 Zinc knuckle Lipase_3 PF01764.20 KLO11732.1 - 1.5e-16 60.2 0.0 2e-16 59.8 0.0 1.2 1 0 0 1 1 1 1 Lipase (class 3) SFTA2 PF15210.1 KLO11732.1 - 0.033 13.7 0.0 0.16 11.5 0.0 2.2 2 0 0 2 2 2 0 Surfactant-associated protein 2 Methyltransf_11 PF08241.7 KLO11733.1 - 5.2e-12 46.1 0.0 8.1e-12 45.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KLO11733.1 - 9.5e-09 35.0 0.0 6.5e-08 32.3 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KLO11733.1 - 2e-07 30.3 0.0 5.6e-07 28.9 0.0 1.7 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.1 KLO11733.1 - 3.3e-07 30.1 0.0 5.1e-07 29.5 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KLO11733.1 - 6.2e-06 26.6 0.0 1.6e-05 25.2 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KLO11733.1 - 7.2e-06 26.3 0.0 1.7e-05 25.1 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KLO11733.1 - 0.00015 22.3 0.0 0.0035 17.8 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.10 KLO11733.1 - 0.0024 17.5 0.0 0.0054 16.3 0.0 1.4 1 1 0 1 1 1 1 Hypothetical methyltransferase FtsJ PF01728.14 KLO11733.1 - 0.0029 17.6 0.0 0.0042 17.0 0.0 1.4 1 0 0 1 1 1 1 FtsJ-like methyltransferase TPMT PF05724.6 KLO11733.1 - 0.054 12.9 0.0 0.12 11.8 0.0 1.5 1 1 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) MTS PF05175.9 KLO11733.1 - 0.067 12.5 0.0 0.11 11.8 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_26 PF13659.1 KLO11733.1 - 0.067 13.2 0.0 0.5 10.4 0.0 2.0 1 1 0 1 1 1 0 Methyltransferase domain DUF3596 PF12167.3 KLO11734.1 - 0.1 12.1 0.0 0.15 11.6 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3596) bZIP_2 PF07716.10 KLO11736.1 - 1.3e-09 37.6 13.4 2.7e-09 36.7 9.3 1.5 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.16 KLO11736.1 - 0.00017 21.4 14.1 0.00052 19.9 9.8 1.8 1 1 0 1 1 1 1 bZIP transcription factor XhlA PF10779.4 KLO11736.1 - 0.006 16.4 0.0 0.01 15.7 0.0 1.3 1 0 0 1 1 1 1 Haemolysin XhlA PAT1 PF09770.4 KLO11736.1 - 4 5.5 9.2 4.7 5.3 6.4 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 RSN1_TM PF13967.1 KLO11738.1 - 0.048 13.2 0.1 0.048 13.2 0.1 1.6 2 0 0 2 2 2 0 Late exocytosis, associated with Golgi transport HCV_NS4a PF01006.15 KLO11738.1 - 0.059 12.9 0.3 0.11 11.9 0.2 1.5 1 0 0 1 1 1 0 Hepatitis C virus non-structural protein NS4a Herpes_gE PF02480.11 KLO11738.1 - 0.14 10.3 0.1 0.19 9.9 0.0 1.1 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E DUF1180 PF06679.7 KLO11738.1 - 0.27 11.1 0.9 0.38 10.6 0.1 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF1180) Gti1_Pac2 PF09729.4 KLO11741.1 - 3.2e-21 75.9 1.0 8.6e-19 68.0 0.0 2.4 2 1 1 3 3 3 2 Gti1/Pac2 family GLTP PF08718.6 KLO11744.1 - 3e-38 131.2 0.0 3.8e-38 130.8 0.0 1.1 1 0 0 1 1 1 1 Glycolipid transfer protein (GLTP) UPF0242 PF06785.6 KLO11744.1 - 0.021 13.4 0.3 0.031 12.9 0.2 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) Prefoldin PF02996.12 KLO11744.1 - 0.075 12.6 0.6 0.23 11.0 0.2 1.9 1 1 0 1 1 1 0 Prefoldin subunit MSG PF02349.10 KLO11744.1 - 0.13 12.2 4.2 0.14 12.1 1.7 1.8 2 0 0 2 2 2 0 Major surface glycoprotein GAF_2 PF13185.1 KLO11745.1 - 0.0037 17.7 0.0 0.0052 17.2 0.0 1.3 1 0 0 1 1 1 1 GAF domain GAF PF01590.21 KLO11745.1 - 0.0068 16.5 0.0 0.014 15.5 0.0 1.6 1 1 0 1 1 1 1 GAF domain Gti1_Pac2 PF09729.4 KLO11747.1 - 7.3e-27 94.2 1.7 2.2e-23 82.9 0.2 2.2 1 1 0 2 2 2 2 Gti1/Pac2 family Gti1_Pac2 PF09729.4 KLO11748.1 - 7.1e-20 71.5 0.0 6.6e-17 61.8 0.0 2.4 1 1 1 2 2 2 2 Gti1/Pac2 family TFIIA PF03153.8 KLO11750.1 - 2e-52 179.3 6.2 4.3e-33 115.7 3.1 2.2 1 1 1 2 2 2 2 Transcription factor IIA, alpha/beta subunit PAT1 PF09770.4 KLO11750.1 - 0.012 13.9 24.6 0.014 13.6 17.1 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 PALP PF00291.20 KLO11751.1 - 8.4e-45 153.3 0.0 3.4e-44 151.3 0.0 1.8 1 1 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme SWIRM PF04433.12 KLO11752.1 - 3.4e-14 52.7 0.0 6.5e-14 51.8 0.0 1.5 1 0 0 1 1 1 1 SWIRM domain Myb_DNA-binding PF00249.26 KLO11752.1 - 9.5e-09 35.1 0.1 2.7e-08 33.7 0.1 1.8 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 KLO11752.1 - 0.0077 16.3 0.0 0.019 15.0 0.0 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain p450 PF00067.17 KLO11753.1 - 1.8e-66 224.5 0.0 2.4e-66 224.1 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 zf-CCCH PF00642.19 KLO11754.1 - 4.2e-09 35.8 2.5 9.2e-09 34.7 1.7 1.6 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-C3HC4_3 PF13920.1 KLO11754.1 - 2.2e-08 33.6 4.5 3.9e-08 32.8 3.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KLO11754.1 - 2.7e-07 30.5 9.6 4.6e-07 29.7 6.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KLO11754.1 - 1.1e-06 28.3 7.8 1.8e-06 27.5 5.4 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.20 KLO11754.1 - 3.3e-05 23.4 8.6 6.1e-05 22.6 6.0 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 KLO11754.1 - 6.4e-05 22.5 2.1 0.00019 21.0 1.5 1.8 1 1 0 1 1 1 1 RING-type zinc-finger zf-RING_2 PF13639.1 KLO11754.1 - 6.9e-05 22.6 6.7 0.00012 21.8 4.6 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_4 PF15227.1 KLO11754.1 - 0.00077 19.2 7.4 0.0017 18.1 5.1 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-Nse PF11789.3 KLO11754.1 - 0.013 14.9 2.0 0.024 14.1 1.4 1.3 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-RanBP PF00641.13 KLO11754.1 - 6.7 5.9 6.9 0.2 10.7 0.5 1.7 2 0 0 2 2 2 0 Zn-finger in Ran binding protein and others DUF3107 PF11305.3 KLO11756.1 - 0.096 12.5 0.0 0.14 12.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3107) Ribosomal_S8e PF01201.17 KLO11757.1 - 5e-37 126.9 8.3 2.5e-36 124.7 5.7 2.0 1 1 0 1 1 1 1 Ribosomal protein S8e Yip1 PF04893.12 KLO11758.1 - 1.4e-11 44.1 11.7 2.4e-11 43.4 8.1 1.4 1 1 0 1 1 1 1 Yip1 domain DUF1168 PF06658.7 KLO11759.1 - 4.3e-39 133.2 14.4 5.8e-39 132.8 10.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1168) ARHGEF5_35 PF15441.1 KLO11759.1 - 0.4 9.4 12.3 0.54 8.9 8.6 1.1 1 0 0 1 1 1 0 Rho guanine nucleotide exchange factor 5/35 SAPS PF04499.10 KLO11759.1 - 3.3 6.2 6.7 3.9 6.0 4.7 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein RNase_H2-Ydr279 PF09468.5 KLO11759.1 - 5.5 6.0 8.7 6.9 5.7 6.0 1.1 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) Vfa1 PF08432.5 KLO11759.1 - 5.7 6.9 15.1 9.1 6.2 10.5 1.3 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 DUF647 PF04884.9 KLO11760.1 - 3.8e-78 262.1 1.5 6.6e-78 261.3 1.0 1.3 1 0 0 1 1 1 1 Vitamin B6 photo-protection and homoeostasis Cwf_Cwc_15 PF04889.7 KLO11760.1 - 0.15 11.7 9.1 0.23 11.1 6.3 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein MULE PF10551.4 KLO11763.1 - 5.4e-07 29.6 0.0 3.1e-06 27.2 0.0 2.2 2 0 0 2 2 2 1 MULE transposase domain HSP70 PF00012.15 KLO11764.1 - 0.012 13.5 0.0 0.017 13.0 0.0 1.1 1 0 0 1 1 1 0 Hsp70 protein Tet_JBP PF12851.2 KLO11765.1 - 5.8e-13 48.4 0.1 1.2e-12 47.4 0.0 1.4 1 0 0 1 1 1 1 Oxygenase domain of the 2OGFeDO superfamily Pheromone PF08015.6 KLO11766.1 - 5.9 7.7 15.6 3.1 8.7 1.8 3.0 3 0 0 3 3 3 0 Fungal mating-type pheromone AAA_16 PF13191.1 KLO11767.1 - 4.4e-06 26.8 0.0 1.5e-05 25.0 0.0 1.9 1 1 0 1 1 1 1 AAA ATPase domain NACHT PF05729.7 KLO11767.1 - 0.00038 20.1 0.0 0.0015 18.2 0.0 2.0 1 1 0 1 1 1 1 NACHT domain AAA_22 PF13401.1 KLO11767.1 - 0.00061 19.9 0.0 0.0046 17.0 0.0 2.2 2 0 0 2 2 2 1 AAA domain NB-ARC PF00931.17 KLO11767.1 - 0.00073 18.4 0.0 0.0012 17.7 0.0 1.4 1 0 0 1 1 1 1 NB-ARC domain KAP_NTPase PF07693.9 KLO11767.1 - 0.015 14.2 0.0 0.022 13.7 0.0 1.3 1 0 0 1 1 1 0 KAP family P-loop domain AAA PF00004.24 KLO11767.1 - 0.025 14.7 0.0 0.088 13.0 0.0 2.0 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.1 KLO11767.1 - 0.15 12.3 0.1 0.5 10.6 0.0 2.1 2 1 0 2 2 2 0 AAA domain CAP PF00188.21 KLO11770.1 - 4.9e-24 85.1 2.1 6.1e-24 84.8 1.4 1.1 1 0 0 1 1 1 1 Cysteine-rich secretory protein family CAP PF00188.21 KLO11772.1 - 2.1e-24 86.3 1.4 2.5e-24 86.1 1.0 1.1 1 0 0 1 1 1 1 Cysteine-rich secretory protein family Methyltransf_2 PF00891.13 KLO11773.1 - 2.8e-32 111.8 0.0 5.5e-32 110.8 0.0 1.4 1 1 0 1 1 1 1 O-methyltransferase MTS PF05175.9 KLO11773.1 - 0.0012 18.2 0.0 0.0029 17.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_23 PF13489.1 KLO11773.1 - 0.0022 17.7 0.0 0.0061 16.2 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain DREV PF05219.7 KLO11773.1 - 0.0055 15.6 0.0 0.05 12.4 0.0 2.3 2 1 0 2 2 2 1 DREV methyltransferase Methyltransf_12 PF08242.7 KLO11773.1 - 0.015 15.7 0.0 0.072 13.5 0.0 2.3 2 1 0 2 2 2 0 Methyltransferase domain Methyltransf_4 PF02390.12 KLO11773.1 - 0.033 13.2 0.0 0.06 12.3 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase PCMT PF01135.14 KLO11773.1 - 0.043 13.3 0.0 0.13 11.8 0.0 1.7 2 0 0 2 2 2 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_18 PF12847.2 KLO11773.1 - 0.074 13.6 0.0 0.19 12.3 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase domain Dimerisation PF08100.6 KLO11773.1 - 0.11 12.3 0.2 0.33 10.8 0.1 1.8 1 0 0 1 1 1 0 Dimerisation domain Methyltransf_31 PF13847.1 KLO11773.1 - 0.15 11.6 0.0 0.39 10.2 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain F-box-like PF12937.2 KLO11774.1 - 5.2e-07 29.2 0.7 5.2e-07 29.2 0.5 3.1 3 0 0 3 3 3 1 F-box-like F-box PF00646.28 KLO11774.1 - 0.031 13.9 3.3 0.23 11.1 2.3 2.5 1 1 0 1 1 1 0 F-box domain Coprogen_oxidas PF01218.13 KLO11775.1 - 5.9e-113 376.3 0.0 1.3e-111 371.8 0.0 2.4 1 1 0 1 1 1 1 Coproporphyrinogen III oxidase Septin PF00735.13 KLO11776.1 - 5.6e-46 156.8 0.1 7.7e-17 61.2 0.0 3.7 4 0 0 4 4 4 3 Septin MMR_HSR1 PF01926.18 KLO11776.1 - 0.00046 20.1 0.0 0.00096 19.0 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 KLO11776.1 - 0.0033 17.9 0.0 0.0066 16.9 0.0 1.5 1 0 0 1 1 1 1 Miro-like protein GTP_EFTU PF00009.22 KLO11776.1 - 0.0059 16.0 0.0 0.01 15.2 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain FtsK_SpoIIIE PF01580.13 KLO11776.1 - 0.011 15.2 0.0 0.023 14.1 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_16 PF13191.1 KLO11776.1 - 0.02 14.8 0.0 0.057 13.4 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain DUF815 PF05673.8 KLO11776.1 - 0.037 12.9 0.0 0.063 12.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Period_C PF12114.3 KLO11776.1 - 0.039 13.5 6.5 0.63 9.6 1.3 2.4 2 0 0 2 2 2 0 Period protein 2/3C-terminal region ABC_tran PF00005.22 KLO11776.1 - 0.05 13.9 0.0 0.13 12.5 0.0 1.7 1 0 0 1 1 1 0 ABC transporter DUF258 PF03193.11 KLO11776.1 - 0.056 12.6 0.0 0.19 10.9 0.0 1.8 1 1 0 1 1 1 0 Protein of unknown function, DUF258 Dynamin_N PF00350.18 KLO11776.1 - 0.061 13.1 0.2 11 5.8 0.0 2.4 1 1 1 2 2 2 0 Dynamin family CM_2 PF01817.16 KLO11777.1 - 3.1e-12 46.3 0.1 1.8e-08 34.3 0.0 3.3 2 1 0 2 2 2 2 Chorismate mutase type II Thi4 PF01946.12 KLO11778.1 - 1.4e-94 315.5 0.1 1.8e-94 315.1 0.1 1.2 1 0 0 1 1 1 1 Thi4 family DAO PF01266.19 KLO11778.1 - 2e-10 40.1 0.6 5.5e-10 38.6 0.2 1.8 1 1 1 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KLO11778.1 - 2.9e-07 30.3 0.1 8.5e-07 28.9 0.1 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 KLO11778.1 - 3.3e-07 29.5 0.4 1e-06 27.9 0.1 1.8 2 0 0 2 2 2 1 Lycopene cyclase protein NAD_binding_9 PF13454.1 KLO11778.1 - 2.8e-06 27.1 1.1 3.7e-05 23.5 0.0 2.6 3 0 0 3 3 3 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 KLO11778.1 - 4e-06 26.8 0.4 7.4e-06 25.9 0.2 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 KLO11778.1 - 3e-05 23.0 1.0 0.00011 21.2 0.2 2.0 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_3 PF13738.1 KLO11778.1 - 0.00024 21.2 0.1 0.00044 20.3 0.1 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 KLO11778.1 - 0.00097 17.7 0.2 0.0016 16.9 0.1 1.4 1 0 0 1 1 1 1 HI0933-like protein FAD_oxidored PF12831.2 KLO11778.1 - 0.0024 16.9 0.4 0.0042 16.2 0.2 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase GIDA PF01134.17 KLO11778.1 - 0.0062 15.4 0.1 0.039 12.8 0.0 2.0 2 0 0 2 2 2 1 Glucose inhibited division protein A Trp_halogenase PF04820.9 KLO11778.1 - 0.03 12.9 0.1 0.046 12.3 0.1 1.2 1 0 0 1 1 1 0 Tryptophan halogenase K_oxygenase PF13434.1 KLO11778.1 - 0.086 11.7 0.0 0.18 10.7 0.0 1.5 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) Glyco_hydro_92 PF07971.7 KLO11779.1 - 1.1e-129 433.4 0.0 1.4e-129 433.0 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 Glycos_transf_3 PF00591.16 KLO11780.1 - 1.2e-73 247.6 0.0 1.5e-73 247.3 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family, a/b domain Glycos_trans_3N PF02885.12 KLO11780.1 - 7.2e-09 35.1 0.0 1.3e-08 34.3 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family, helical bundle domain F-box-like PF12937.2 KLO11781.1 - 7.3e-07 28.8 1.1 2.5e-06 27.1 0.7 2.0 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KLO11781.1 - 0.076 12.6 3.1 1.3 8.8 2.0 3.1 1 1 0 1 1 1 0 F-box domain LRR_4 PF12799.2 KLO11781.1 - 0.11 12.1 1.4 15 5.3 0.1 3.7 3 0 0 3 3 3 0 Leucine Rich repeats (2 copies) F-box-like PF12937.2 KLO11782.1 - 7.1e-06 25.6 1.3 9.9e-05 21.9 0.2 2.8 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 KLO11782.1 - 0.019 14.5 1.1 0.13 11.9 0.1 2.8 2 0 0 2 2 2 0 F-box domain APH PF01636.18 KLO11783.1 - 3.5e-08 33.4 1.2 6.7e-08 32.5 0.9 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 KLO11783.1 - 3.1e-05 23.6 0.0 4.5e-05 23.1 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase MFS_1 PF07690.11 KLO11784.1 - 8.3e-26 90.5 50.1 1.4e-23 83.1 26.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Folate_carrier PF01770.13 KLO11784.1 - 0.00015 20.4 7.7 0.00039 19.0 5.3 1.7 1 0 0 1 1 1 1 Reduced folate carrier Diphthamide_syn PF01866.12 KLO11785.1 - 1.7e-64 217.9 0.0 2.3e-64 217.5 0.0 1.1 1 0 0 1 1 1 1 Putative diphthamide synthesis protein DRP PF06044.7 KLO11787.1 - 0.02 13.9 0.1 0.02 13.9 0.1 1.1 1 0 0 1 1 1 0 Dam-replacing family Cytochrome_C554 PF13435.1 KLO11787.1 - 0.085 12.9 1.2 0.11 12.5 0.8 1.2 1 0 0 1 1 1 0 Cytochrome c554 and c-prime Pro-kuma_activ PF09286.6 KLO11791.1 - 1.5e-43 148.2 0.0 4.2e-43 146.8 0.0 1.7 2 0 0 2 2 2 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.17 KLO11791.1 - 5.4e-05 22.4 1.6 0.0001 21.5 1.1 1.4 1 0 0 1 1 1 1 Subtilase family Chitin_synth_1 PF01644.12 KLO11794.1 - 7.6e-87 289.2 0.3 1.2e-86 288.5 0.2 1.3 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.6 KLO11794.1 - 1.5e-31 107.9 0.3 2.5e-30 103.9 0.6 2.6 3 0 0 3 3 3 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.10 KLO11794.1 - 1.7e-23 82.8 0.3 8e-18 64.1 0.0 2.2 2 0 0 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.1 KLO11794.1 - 6.6e-07 29.2 0.7 6.6e-07 29.2 0.5 2.4 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 KLO11794.1 - 1.6e-06 28.0 0.0 4.2e-06 26.7 0.0 1.7 2 0 0 2 2 2 1 Glycosyltransferase like family 2 AdoMet_MTase PF07757.8 KLO11796.1 - 7.9e-35 119.3 0.1 2.3e-16 59.9 0.0 2.2 2 0 0 2 2 2 2 Predicted AdoMet-dependent methyltransferase Methyltransf_23 PF13489.1 KLO11796.1 - 0.0012 18.5 0.0 0.0026 17.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MetW PF07021.7 KLO11796.1 - 0.12 11.7 0.0 0.21 10.9 0.0 1.3 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Methyltransf_31 PF13847.1 KLO11796.1 - 0.2 11.2 0.0 0.36 10.3 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain VQ PF05678.9 KLO11797.1 - 0.072 12.1 0.1 0.11 11.5 0.0 1.3 1 0 0 1 1 1 0 VQ motif Indigoidine_A PF04227.7 KLO11798.1 - 0.048 12.8 0.0 0.086 12.0 0.0 1.3 1 0 0 1 1 1 0 Indigoidine synthase A like protein Leader_Erm PF08253.6 KLO11799.1 - 0.015 14.7 0.7 0.034 13.5 0.5 1.5 1 0 0 1 1 1 0 Erm Leader peptide EF-hand_1 PF00036.27 KLO11799.1 - 0.018 14.3 0.1 0.066 12.5 0.1 2.1 1 0 0 1 1 1 0 EF hand DUF1297 PF06973.7 KLO11799.1 - 0.029 13.6 0.3 0.81 8.9 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF1297) EF-hand_6 PF13405.1 KLO11799.1 - 0.032 14.1 0.0 0.2 11.6 0.0 2.3 2 0 0 2 2 2 0 EF-hand domain ApoLp-III PF07464.6 KLO11799.1 - 10 6.1 13.7 6.9 6.6 0.8 4.4 5 0 0 5 5 5 0 Apolipophorin-III precursor (apoLp-III) EF-hand_6 PF13405.1 KLO11800.1 - 0.026 14.3 0.1 0.29 11.1 0.0 2.7 2 0 0 2 2 2 0 EF-hand domain EF-hand_1 PF00036.27 KLO11800.1 - 0.026 13.7 0.1 0.097 12.0 0.1 2.1 1 0 0 1 1 1 0 EF hand Leader_Erm PF08253.6 KLO11800.1 - 0.14 11.6 0.5 0.34 10.4 0.4 1.5 1 0 0 1 1 1 0 Erm Leader peptide adh_short PF00106.20 KLO11801.1 - 2.3e-20 73.1 0.7 2.3e-19 69.9 0.5 2.0 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KLO11801.1 - 4.2e-13 49.6 0.0 1.9e-12 47.4 0.0 1.8 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KLO11801.1 - 1.3e-06 28.1 0.3 1.1e-05 25.2 0.1 2.0 2 0 0 2 2 2 1 KR domain Pyr_redox PF00070.22 KLO11801.1 - 0.0054 17.1 0.4 0.0098 16.2 0.3 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Epimerase PF01370.16 KLO11801.1 - 0.036 13.4 0.1 0.27 10.6 0.0 2.0 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family MBOAT_2 PF13813.1 KLO11802.1 - 2e-14 53.3 4.1 2e-14 53.3 2.8 1.8 2 0 0 2 2 2 1 Membrane bound O-acyl transferase family MBOAT PF03062.14 KLO11802.1 - 0.0052 15.9 7.0 0.0094 15.1 4.4 1.7 1 1 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family DUF902 PF06001.8 KLO11804.1 - 7.1 6.8 7.8 28 4.9 0.1 2.8 2 1 0 2 2 2 0 Domain of Unknown Function (DUF902) MFS_1 PF07690.11 KLO11805.1 - 9e-06 24.6 0.5 1.3e-05 24.1 0.3 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF1778 PF08681.6 KLO11806.1 - 0.074 12.8 0.0 1.1 9.1 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1778) DnaJ PF00226.26 KLO11806.1 - 0.1 12.3 0.0 0.14 11.9 0.0 1.3 1 0 0 1 1 1 0 DnaJ domain BATS PF06968.8 KLO11806.1 - 0.13 12.1 0.0 0.24 11.2 0.0 1.6 1 1 0 1 1 1 0 Biotin and Thiamin Synthesis associated domain CNH PF00780.17 KLO11807.1 - 9.2e-26 90.8 0.0 5.7e-19 68.5 0.0 2.0 2 0 0 2 2 2 2 CNH domain EPTP PF03736.12 KLO11807.1 - 0.15 11.8 0.0 0.81 9.4 0.0 2.2 2 0 0 2 2 2 0 EPTP domain CNH PF00780.17 KLO11808.1 - 3.3e-23 82.4 0.0 4.2e-23 82.1 0.0 1.0 1 0 0 1 1 1 1 CNH domain DUF4443 PF14544.1 KLO11808.1 - 0.017 15.0 0.0 0.032 14.1 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4443) zf-C2H2_4 PF13894.1 KLO11810.1 - 0.00058 20.0 0.0 2.2 8.8 0.0 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.21 KLO11810.1 - 0.12 12.7 5.7 0.15 12.4 0.1 3.1 3 0 0 3 3 3 0 Zinc finger, C2H2 type Saccharop_dh PF03435.13 KLO11811.1 - 7.4e-06 25.1 0.0 1.1e-05 24.6 0.0 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase NAD_binding_10 PF13460.1 KLO11811.1 - 3.4e-05 23.9 0.1 4.9e-05 23.4 0.0 1.4 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 KLO11811.1 - 4.8e-05 22.9 0.1 0.00086 18.8 0.0 2.3 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family Semialdhyde_dh PF01118.19 KLO11811.1 - 5.7e-05 23.3 0.0 0.00014 22.1 0.0 1.6 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain ADH_zinc_N PF00107.21 KLO11811.1 - 0.00025 20.6 0.5 0.0011 18.5 0.1 2.0 2 0 0 2 2 2 1 Zinc-binding dehydrogenase NmrA PF05368.8 KLO11811.1 - 0.0076 15.5 0.0 0.015 14.5 0.0 1.5 1 0 0 1 1 1 1 NmrA-like family NAD_binding_4 PF07993.7 KLO11811.1 - 0.11 11.4 0.0 0.2 10.5 0.0 1.6 1 1 0 1 1 1 0 Male sterility protein Epimerase PF01370.16 KLO11812.1 - 1e-05 25.1 0.0 0.00015 21.3 0.0 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Saccharop_dh PF03435.13 KLO11812.1 - 4.6e-05 22.5 0.0 6.5e-05 22.0 0.0 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase NAD_binding_10 PF13460.1 KLO11812.1 - 0.00099 19.1 0.0 0.0012 18.8 0.0 1.3 1 1 0 1 1 1 1 NADH(P)-binding Semialdhyde_dh PF01118.19 KLO11812.1 - 0.0013 18.9 0.0 0.003 17.8 0.0 1.6 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain NmrA PF05368.8 KLO11812.1 - 0.0073 15.5 0.0 0.012 14.9 0.0 1.4 1 0 0 1 1 1 1 NmrA-like family NAD_binding_4 PF07993.7 KLO11812.1 - 0.083 11.7 0.0 0.13 11.2 0.0 1.4 1 0 0 1 1 1 0 Male sterility protein Tox-HNH-EHHH PF15657.1 KLO11812.1 - 0.16 12.1 1.7 0.27 11.4 1.2 1.3 1 0 0 1 1 1 0 HNH/Endo VII superfamily nuclease toxins Saccharop_dh PF03435.13 KLO11813.1 - 7.1e-07 28.5 0.1 1e-06 28.0 0.1 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase NAD_binding_10 PF13460.1 KLO11813.1 - 3.9e-06 26.9 0.1 5.2e-06 26.5 0.1 1.3 1 0 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 KLO11813.1 - 1.1e-05 24.7 0.2 1.9e-05 24.0 0.1 1.4 1 0 0 1 1 1 1 NmrA-like family Semialdhyde_dh PF01118.19 KLO11813.1 - 0.00018 21.7 0.0 0.00036 20.8 0.0 1.5 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain NAD_binding_4 PF07993.7 KLO11813.1 - 0.0026 16.7 0.0 0.0039 16.1 0.0 1.4 1 0 0 1 1 1 1 Male sterility protein Epimerase PF01370.16 KLO11813.1 - 0.0094 15.4 0.0 0.061 12.7 0.0 2.0 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family adh_short PF00106.20 KLO11813.1 - 0.37 10.7 4.6 1.8 8.4 3.2 2.1 1 1 0 1 1 1 0 short chain dehydrogenase ICMT PF04140.9 KLO11814.1 - 7.9e-10 38.8 0.1 2.3e-09 37.2 0.0 1.7 2 0 0 2 2 2 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family DUF1295 PF06966.7 KLO11814.1 - 6.5e-06 25.6 0.0 7.7e-06 25.3 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) PEMT PF04191.8 KLO11814.1 - 9.4e-06 25.6 0.5 2.3e-05 24.4 0.0 1.8 2 0 0 2 2 2 1 Phospholipid methyltransferase ERG4_ERG24 PF01222.12 KLO11814.1 - 0.0015 17.1 0.0 0.0025 16.4 0.0 1.3 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family 2OG-FeII_Oxy_3 PF13640.1 KLO11815.1 - 0.00011 22.6 0.0 0.00023 21.6 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.15 KLO11815.1 - 0.0029 17.8 0.0 0.0054 16.9 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Lipocalin_3 PF12702.2 KLO11816.1 - 0.058 13.4 0.0 0.2 11.6 0.0 1.8 2 0 0 2 2 2 0 Lipocalin-like Pmp3 PF01679.12 KLO11817.1 - 8.9e-19 66.9 11.9 1.2e-18 66.5 8.2 1.2 1 0 0 1 1 1 1 Proteolipid membrane potential modulator TPR_12 PF13424.1 KLO11821.1 - 7.2e-31 105.9 22.1 1.2e-09 37.9 0.1 4.7 1 1 4 5 5 5 5 Tetratricopeptide repeat TPR_10 PF13374.1 KLO11821.1 - 1.4e-25 88.3 6.2 0.0044 16.9 0.0 6.5 6 0 0 6 6 6 6 Tetratricopeptide repeat DUF3856 PF12968.2 KLO11821.1 - 2.4e-05 24.2 4.4 0.003 17.3 0.2 3.5 3 0 0 3 3 3 1 Domain of Unknown Function (DUF3856) AAA_16 PF13191.1 KLO11821.1 - 7.8e-05 22.7 0.2 0.002 18.1 0.0 3.2 2 1 0 2 2 2 1 AAA ATPase domain NACHT PF05729.7 KLO11821.1 - 0.0029 17.3 0.0 0.0069 16.0 0.0 1.7 1 0 0 1 1 1 1 NACHT domain TPR_11 PF13414.1 KLO11821.1 - 0.0029 17.2 17.3 0.42 10.3 0.3 5.9 2 1 4 7 7 7 2 TPR repeat TPR_17 PF13431.1 KLO11821.1 - 0.0056 16.7 3.8 78 3.8 0.0 6.2 6 0 0 6 6 5 0 Tetratricopeptide repeat AAA_19 PF13245.1 KLO11821.1 - 0.0076 15.9 0.0 0.023 14.4 0.0 1.8 1 0 0 1 1 1 1 Part of AAA domain DUF4404 PF14357.1 KLO11821.1 - 0.014 15.8 3.3 5 7.6 0.0 4.3 4 0 0 4 4 3 0 Domain of unknown function (DUF4404) AAA_25 PF13481.1 KLO11821.1 - 0.015 14.7 0.0 0.083 12.2 0.0 2.3 3 0 0 3 3 3 0 AAA domain Zeta_toxin PF06414.7 KLO11821.1 - 0.066 12.3 0.0 0.27 10.2 0.0 2.0 1 0 0 1 1 1 0 Zeta toxin TPR_2 PF07719.12 KLO11821.1 - 0.085 12.8 5.6 6.9 6.8 0.0 5.9 6 1 0 6 6 6 0 Tetratricopeptide repeat AAA_17 PF13207.1 KLO11821.1 - 0.17 12.6 0.3 1.1 10.0 0.1 2.6 2 0 0 2 2 2 0 AAA domain TPR_16 PF13432.1 KLO11821.1 - 0.23 12.1 10.5 0.96 10.2 0.0 4.8 3 1 3 6 6 5 0 Tetratricopeptide repeat AAA_23 PF13476.1 KLO11821.1 - 0.29 11.4 0.9 0.62 10.3 0.0 1.9 2 0 0 2 2 2 0 AAA domain Pmp3 PF01679.12 KLO11822.1 - 4e-18 64.8 12.0 5.7e-18 64.3 8.3 1.2 1 0 0 1 1 1 1 Proteolipid membrane potential modulator Pmp3 PF01679.12 KLO11823.1 - 2e-09 37.0 6.2 2.3e-09 36.7 4.0 1.5 1 1 1 2 2 2 1 Proteolipid membrane potential modulator Pmp3 PF01679.12 KLO11825.1 - 7.2e-13 48.0 1.0 8.2e-13 47.8 0.7 1.2 1 0 0 1 1 1 1 Proteolipid membrane potential modulator Pmp3 PF01679.12 KLO11826.1 - 6.8e-16 57.7 4.8 1.4e-15 56.6 3.3 1.5 1 0 0 1 1 1 1 Proteolipid membrane potential modulator FAD_binding_4 PF01565.18 KLO11827.1 - 4.2e-23 81.3 0.3 8.6e-23 80.3 0.2 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 KLO11827.1 - 0.0032 17.3 0.0 0.0074 16.1 0.0 1.6 1 0 0 1 1 1 1 Berberine and berberine like APH PF01636.18 KLO11828.1 - 1.8e-15 57.3 1.3 3.3e-09 36.8 0.0 2.7 3 0 0 3 3 3 2 Phosphotransferase enzyme family Oxidored-like PF09791.4 KLO11829.1 - 2.7e-16 58.7 0.4 6.1e-16 57.5 0.3 1.6 1 0 0 1 1 1 1 Oxidoreductase-like protein, N-terminal DUF1244 PF06844.6 KLO11829.1 - 0.17 11.7 0.6 2.6 7.9 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1244) PCNA_N PF00705.13 KLO11830.1 - 2.6e-51 172.4 3.0 2.6e-50 169.1 1.0 2.3 2 0 0 2 2 2 1 Proliferating cell nuclear antigen, N-terminal domain PCNA_C PF02747.10 KLO11830.1 - 2e-39 134.4 0.1 2.9e-18 66.0 0.0 3.1 3 0 0 3 3 3 2 Proliferating cell nuclear antigen, C-terminal domain Rad1 PF02144.11 KLO11830.1 - 1.5e-06 27.2 3.5 0.00044 19.1 2.4 3.0 1 1 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 Rad9 PF04139.8 KLO11830.1 - 1.7e-06 27.3 0.0 6.5e-06 25.4 0.0 1.8 2 0 0 2 2 2 1 Rad9 Hus1 PF04005.7 KLO11830.1 - 0.0021 17.0 2.9 0.16 10.8 2.0 3.4 1 1 0 1 1 1 1 Hus1-like protein OMP_b-brl PF13505.1 KLO11830.1 - 0.057 13.3 0.0 0.1 12.5 0.0 1.4 1 0 0 1 1 1 0 Outer membrane protein beta-barrel domain Nop14 PF04147.7 KLO11830.1 - 1 7.2 42.2 1.6 6.5 29.3 1.2 1 0 0 1 1 1 0 Nop14-like family DUF2077 PF09850.4 KLO11831.1 - 0.034 13.5 0.0 0.037 13.4 0.0 1.0 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2077) Ammonium_transp PF00909.16 KLO11834.1 - 6.3e-114 380.5 27.5 7.3e-114 380.3 19.1 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family 2OG-FeII_Oxy_3 PF13640.1 KLO11835.1 - 3.4e-06 27.4 0.0 2.5e-05 24.7 0.0 2.4 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.15 KLO11835.1 - 0.00048 20.3 0.0 0.0012 19.1 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily TPR_12 PF13424.1 KLO11838.1 - 3e-46 155.2 32.2 8.6e-10 38.4 0.2 8.4 5 2 5 10 10 10 8 Tetratricopeptide repeat TPR_10 PF13374.1 KLO11838.1 - 1.6e-44 148.5 39.1 2.3e-05 24.1 0.1 12.6 12 0 0 12 12 12 10 Tetratricopeptide repeat TPR_11 PF13414.1 KLO11838.1 - 4.6e-12 45.4 33.5 0.0052 16.4 0.6 8.7 3 1 8 11 11 10 7 TPR repeat DUF4404 PF14357.1 KLO11838.1 - 6.2e-11 42.5 15.2 1.3 9.4 0.0 9.0 8 2 0 9 9 8 3 Domain of unknown function (DUF4404) NACHT PF05729.7 KLO11838.1 - 4.4e-06 26.4 0.0 1.1e-05 25.1 0.0 1.7 1 0 0 1 1 1 1 NACHT domain Apc5 PF12862.2 KLO11838.1 - 5.1e-06 26.2 17.3 1.7 8.5 0.1 8.8 3 3 6 9 9 9 2 Anaphase-promoting complex subunit 5 DUF3856 PF12968.2 KLO11838.1 - 7.6e-06 25.8 15.6 0.34 10.7 1.8 5.5 3 2 0 4 4 4 3 Domain of Unknown Function (DUF3856) AAA_16 PF13191.1 KLO11838.1 - 1.5e-05 25.1 0.0 1.5e-05 25.1 0.0 4.7 4 1 0 4 4 4 1 AAA ATPase domain TPR_6 PF13174.1 KLO11838.1 - 4.2e-05 23.7 9.6 21 5.8 0.0 8.3 8 0 0 8 8 7 0 Tetratricopeptide repeat TPR_16 PF13432.1 KLO11838.1 - 0.00051 20.6 13.7 4.6 8.0 0.0 7.2 4 2 2 7 7 7 2 Tetratricopeptide repeat AAA_19 PF13245.1 KLO11838.1 - 0.0018 17.9 0.0 0.011 15.4 0.0 2.3 2 0 0 2 2 2 1 Part of AAA domain AAA_25 PF13481.1 KLO11838.1 - 0.0047 16.3 0.0 0.037 13.4 0.0 2.6 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 KLO11838.1 - 0.01 15.9 0.4 0.61 10.2 0.0 3.8 3 1 0 3 3 3 0 AAA domain AAA_18 PF13238.1 KLO11838.1 - 0.023 14.9 0.3 1.7 8.9 0.0 3.6 3 0 0 3 3 3 0 AAA domain YflT PF11181.3 KLO11838.1 - 0.041 14.0 0.8 31 4.7 0.0 5.4 6 0 0 6 6 5 0 Heat induced stress protein YflT AAA_17 PF13207.1 KLO11838.1 - 0.12 13.2 0.9 0.89 10.3 0.0 3.1 3 1 0 3 3 2 0 AAA domain NTPase_1 PF03266.10 KLO11838.1 - 0.15 11.7 0.0 0.46 10.1 0.0 1.8 1 0 0 1 1 1 0 NTPase AAA_23 PF13476.1 KLO11838.1 - 1.5 9.0 0.0 1.5 9.0 0.0 2.5 3 0 0 3 3 2 0 AAA domain Peptidase_M16 PF00675.15 KLO11838.1 - 2.1 8.1 10.9 2.2 8.0 0.1 4.9 3 1 2 6 6 6 0 Insulinase (Peptidase family M16) TPR_17 PF13431.1 KLO11838.1 - 8.7 6.8 31.3 19 5.7 0.0 9.9 12 0 0 12 12 8 0 Tetratricopeptide repeat zf-C2H2_6 PF13912.1 KLO11843.1 - 0.091 12.7 0.3 0.091 12.7 0.2 2.4 2 0 0 2 2 2 0 C2H2-type zinc finger Chromo PF00385.19 KLO11845.1 - 1.9e-12 46.6 2.2 2.5e-12 46.2 1.6 1.2 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Tudor-knot PF11717.3 KLO11845.1 - 0.013 15.1 0.6 0.032 13.9 0.4 1.7 1 1 0 1 1 1 0 RNA binding activity-knot of a chromodomain LUC7 PF03194.10 KLO11847.1 - 4.8e-74 249.0 0.9 6e-74 248.7 0.7 1.0 1 0 0 1 1 1 1 LUC7 N_terminus DnaJ PF00226.26 KLO11848.1 - 3.6e-18 65.0 0.1 2e-17 62.6 0.0 2.3 2 0 0 2 2 2 1 DnaJ domain Ank_4 PF13637.1 KLO11848.1 - 6.1e-15 55.2 0.0 1.4e-14 54.1 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_2 PF12796.2 KLO11848.1 - 3.8e-13 49.5 0.0 1e-12 48.1 0.0 1.7 2 0 0 2 2 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.1 KLO11848.1 - 2.4e-12 46.6 0.1 1.1e-08 34.9 0.0 2.6 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 KLO11848.1 - 2.1e-11 42.8 0.0 0.00018 21.4 0.0 3.8 4 0 0 4 4 3 2 Ankyrin repeat Ank PF00023.25 KLO11848.1 - 3.6e-11 42.2 0.1 1.7e-06 27.5 0.0 2.8 3 0 0 3 3 3 2 Ankyrin repeat LMBR1 PF04791.11 KLO11848.1 - 0.56 8.7 2.3 0.65 8.5 1.6 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF1675 PF07897.6 KLO11848.1 - 0.59 9.9 16.2 1 9.1 11.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) Vfa1 PF08432.5 KLO11848.1 - 1.5 8.8 19.5 1.1 9.2 11.5 2.0 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 Borrelia_P83 PF05262.6 KLO11848.1 - 2.2 6.4 20.5 3.1 5.9 14.2 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein Hid1 PF12722.2 KLO11848.1 - 6.3 4.3 9.1 9 3.8 6.3 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Neur_chan_memb PF02932.11 KLO11848.1 - 8.8 6.1 7.7 19 5.0 5.4 1.5 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Exo_endo_phos PF03372.18 KLO11849.1 - 5.8e-23 82.1 0.0 7.7e-23 81.7 0.0 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.1 KLO11849.1 - 0.00017 21.1 0.0 0.00045 19.8 0.0 1.7 1 1 0 1 1 1 1 Endonuclease-reverse transcriptase BRCT PF00533.21 KLO11850.1 - 0.00042 20.3 0.0 0.025 14.7 0.0 2.8 2 1 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain DUF4537 PF15057.1 KLO11850.1 - 0.0023 17.7 0.0 0.0062 16.3 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4537) DUF1325 PF07039.6 KLO11850.1 - 0.0033 17.0 0.2 0.014 15.0 0.1 2.1 2 1 0 2 2 2 1 SGF29 tudor-like domain Rad9_Rad53_bind PF08605.5 KLO11850.1 - 0.019 14.7 0.0 0.036 13.8 0.0 1.4 1 0 0 1 1 1 0 Fungal Rad9-like Rad53-binding DUF2341 PF10102.4 KLO11850.1 - 0.098 12.8 0.0 0.23 11.6 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF2341) DUF3472 PF11958.3 KLO11850.1 - 0.14 12.4 0.0 0.32 11.3 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3472) FlgN PF05130.7 KLO11851.1 - 4.2 7.6 8.2 1.2 9.3 3.3 1.9 2 0 0 2 2 2 0 FlgN protein WBS_methylT PF12589.3 KLO11854.1 - 1.7e-20 73.3 8.1 2.9e-20 72.5 5.6 1.4 1 0 0 1 1 1 1 Methyltransferase involved in Williams-Beuren syndrome Methyltransf_11 PF08241.7 KLO11854.1 - 1.4e-09 38.2 0.0 2.9e-09 37.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KLO11854.1 - 4.1e-08 33.1 0.0 7.2e-08 32.3 0.0 1.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KLO11854.1 - 3.1e-05 23.6 0.0 6.5e-05 22.5 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KLO11854.1 - 4.4e-05 23.8 0.0 0.00014 22.2 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KLO11854.1 - 9.7e-05 22.9 0.0 0.00013 22.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KLO11854.1 - 0.00045 20.5 0.0 0.0009 19.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain AdoMet_MTase PF07757.8 KLO11854.1 - 0.012 15.6 0.0 0.023 14.7 0.0 1.4 1 0 0 1 1 1 0 Predicted AdoMet-dependent methyltransferase Methyltransf_26 PF13659.1 KLO11854.1 - 0.015 15.3 0.0 0.026 14.5 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain PCMT PF01135.14 KLO11854.1 - 0.12 11.9 0.0 0.18 11.3 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) TRAPP PF04051.11 KLO11855.1 - 1.9e-37 128.1 0.0 2.8e-37 127.5 0.0 1.2 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component Oxidored_q2 PF00420.19 KLO11856.1 - 7 6.3 13.8 0.83 9.2 2.3 2.5 3 0 0 3 3 3 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L Vac_ImportDeg PF09783.4 KLO11857.1 - 3e-56 189.7 0.1 2.9e-50 170.2 0.0 2.1 2 0 0 2 2 2 2 Vacuolar import and degradation protein Pyr_redox_3 PF13738.1 KLO11858.1 - 6.7e-21 75.2 0.0 1.5e-20 74.1 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KLO11858.1 - 3.2e-11 43.0 0.0 8.3e-11 41.7 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.1 KLO11858.1 - 3.9e-10 39.1 0.1 1.2e-08 34.3 0.0 2.7 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) FMO-like PF00743.14 KLO11858.1 - 4.2e-09 35.1 0.3 1.4e-08 33.4 0.1 1.9 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like DAO PF01266.19 KLO11858.1 - 0.00012 21.0 0.0 0.00025 20.0 0.0 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 KLO11858.1 - 0.00049 20.0 0.0 0.0027 17.5 0.0 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 KLO11858.1 - 0.0059 15.7 0.1 0.012 14.6 0.1 1.5 1 0 0 1 1 1 1 Thi4 family FAD_binding_2 PF00890.19 KLO11858.1 - 0.0079 15.0 0.1 0.028 13.2 0.2 1.7 2 0 0 2 2 2 1 FAD binding domain FAD_binding_3 PF01494.14 KLO11858.1 - 0.055 12.5 0.2 0.092 11.7 0.1 1.3 1 0 0 1 1 1 0 FAD binding domain GIDA PF01134.17 KLO11858.1 - 0.081 11.7 0.2 10 4.8 0.0 2.2 2 0 0 2 2 2 0 Glucose inhibited division protein A Pkinase PF00069.20 KLO11859.1 - 5.2e-37 127.3 0.0 6.6e-37 127.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KLO11859.1 - 5.3e-13 48.6 0.0 7e-13 48.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 KLO11859.1 - 0.00097 18.9 0.1 1.3 8.6 0.0 2.6 2 1 0 3 3 3 2 Phosphotransferase enzyme family JmjC PF02373.17 KLO11861.1 - 6e-08 32.9 0.0 1e-07 32.1 0.0 1.4 1 0 0 1 1 1 1 JmjC domain, hydroxylase WRKY PF03106.10 KLO11861.1 - 0.79 9.6 5.0 0.31 10.8 0.1 2.6 3 0 0 3 3 3 0 WRKY DNA -binding domain DUF1720 PF08226.6 KLO11862.1 - 1.4 9.0 10.3 18 5.4 4.6 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF1720) zf-RING_5 PF14634.1 KLO11863.1 - 2.3e-09 36.8 7.5 3e-09 36.4 5.2 1.2 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.1 KLO11863.1 - 1.5 8.3 13.9 3.1 7.4 0.2 2.4 2 1 0 2 2 2 0 Prokaryotic RING finger family 4 zf-C3HC4_3 PF13920.1 KLO11863.1 - 1.6 8.4 11.8 6.1 6.5 8.2 1.8 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KLO11863.1 - 5.5 7.1 11.2 22 5.1 7.9 1.9 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) G-patch_2 PF12656.2 KLO11864.1 - 3.5e-24 84.4 0.0 3.5e-24 84.4 0.0 2.9 3 1 0 3 3 3 1 DExH-box splicing factor binding site G-patch PF01585.18 KLO11864.1 - 0.034 13.9 0.8 0.083 12.6 0.2 1.9 2 0 0 2 2 2 0 G-patch domain ATP-synt_D PF01813.12 KLO11865.1 - 8.1e-64 214.7 4.3 1e-63 214.4 3.0 1.1 1 0 0 1 1 1 1 ATP synthase subunit D Methyltransf_23 PF13489.1 KLO11866.1 - 1e-12 48.1 0.0 1.5e-12 47.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KLO11866.1 - 5.2e-12 45.5 0.0 5e-11 42.4 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KLO11866.1 - 4.2e-10 39.9 0.0 1e-09 38.7 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KLO11866.1 - 2.2e-08 34.4 0.0 6.1e-08 33.0 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KLO11866.1 - 2.8e-06 27.8 0.1 5.8e-05 23.6 0.1 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KLO11866.1 - 0.0002 21.4 0.2 0.00094 19.1 0.2 2.0 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KLO11866.1 - 0.00025 20.4 0.0 0.0084 15.5 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_25 PF13649.1 KLO11866.1 - 0.00039 20.7 0.0 0.001 19.4 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 KLO11866.1 - 0.00077 18.5 0.0 0.0017 17.4 0.0 1.5 1 0 0 1 1 1 1 Putative methyltransferase FtsJ PF01728.14 KLO11866.1 - 0.0072 16.3 0.0 0.011 15.7 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_29 PF03141.11 KLO11866.1 - 0.018 13.4 0.0 2.5 6.3 0.0 2.1 2 0 0 2 2 2 0 Putative S-adenosyl-L-methionine-dependent methyltransferase GidB PF02527.10 KLO11866.1 - 0.018 14.1 0.0 1.9 7.5 0.0 2.2 2 0 0 2 2 2 0 rRNA small subunit methyltransferase G PrmA PF06325.8 KLO11866.1 - 0.03 13.4 0.0 0.046 12.8 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Ubie_methyltran PF01209.13 KLO11866.1 - 0.043 12.9 0.0 7.1 5.6 0.0 2.2 2 0 0 2 2 2 0 ubiE/COQ5 methyltransferase family FRG1 PF06229.7 KLO11867.1 - 3.1e-19 69.2 0.1 3.1e-19 69.2 0.1 2.4 3 0 0 3 3 3 1 FRG1-like family Fascin PF06268.8 KLO11867.1 - 4e-05 23.6 0.0 0.00019 21.5 0.0 2.0 2 0 0 2 2 2 1 Fascin domain BCS1_N PF08740.6 KLO11868.1 - 1.4e-51 174.7 1.1 1.9e-51 174.3 0.7 1.1 1 0 0 1 1 1 1 BCS1 N terminal AAA PF00004.24 KLO11868.1 - 6.4e-20 71.6 0.0 1.2e-19 70.7 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 KLO11868.1 - 1.3e-05 25.9 0.0 3.3e-05 24.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.1 KLO11868.1 - 0.00018 20.9 0.0 0.0004 19.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 KLO11868.1 - 0.00024 21.0 0.2 0.0012 18.7 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 KLO11868.1 - 0.00083 19.3 1.5 0.0042 17.0 0.3 2.6 2 1 0 2 2 2 1 AAA ATPase domain AAA_18 PF13238.1 KLO11868.1 - 0.0038 17.5 0.0 0.0089 16.3 0.0 1.6 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.1 KLO11868.1 - 0.0042 16.5 0.0 0.011 15.1 0.0 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_22 PF13401.1 KLO11868.1 - 0.0046 17.1 0.0 0.013 15.6 0.0 1.9 1 0 0 1 1 1 1 AAA domain DUF815 PF05673.8 KLO11868.1 - 0.0086 15.0 0.0 0.014 14.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) RNA_helicase PF00910.17 KLO11868.1 - 0.01 15.9 0.0 0.018 15.2 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_5 PF07728.9 KLO11868.1 - 0.011 15.4 0.1 0.066 12.9 0.0 2.4 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_19 PF13245.1 KLO11868.1 - 0.033 13.9 0.0 0.19 11.4 0.0 2.4 1 0 0 1 1 1 0 Part of AAA domain ABC_tran PF00005.22 KLO11868.1 - 0.043 14.1 0.0 0.094 13.0 0.0 1.6 1 0 0 1 1 1 0 ABC transporter Zeta_toxin PF06414.7 KLO11868.1 - 0.044 12.8 0.0 0.11 11.5 0.0 1.7 2 0 0 2 2 2 0 Zeta toxin FtsK_SpoIIIE PF01580.13 KLO11868.1 - 0.062 12.7 0.0 0.13 11.6 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family Viral_helicase1 PF01443.13 KLO11868.1 - 0.078 12.4 0.0 0.16 11.4 0.0 1.5 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_23 PF13476.1 KLO11868.1 - 0.092 13.0 0.0 0.14 12.4 0.0 1.2 1 0 0 1 1 1 0 AAA domain Ras PF00071.17 KLO11869.1 - 7.8e-51 171.6 0.0 9.4e-51 171.4 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KLO11869.1 - 3.4e-16 59.8 0.0 5.9e-16 59.0 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KLO11869.1 - 6.6e-11 41.7 0.0 9.4e-11 41.2 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 KLO11869.1 - 0.0003 20.0 0.0 0.00038 19.6 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region G-alpha PF00503.15 KLO11869.1 - 0.0026 16.5 0.9 0.22 10.1 0.0 2.9 2 1 1 3 3 3 1 G-protein alpha subunit RNA_helicase PF00910.17 KLO11869.1 - 0.0086 16.2 0.1 0.14 12.3 0.1 2.1 1 1 0 1 1 1 1 RNA helicase Pox_A32 PF04665.7 KLO11869.1 - 0.029 13.6 0.1 0.049 12.9 0.1 1.3 1 0 0 1 1 1 0 Poxvirus A32 protein AAA_33 PF13671.1 KLO11869.1 - 0.04 13.7 0.0 0.07 12.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.1 KLO11869.1 - 0.082 13.0 0.1 0.17 12.0 0.1 1.7 1 1 0 1 1 1 0 AAA domain Ribosomal_S13 PF00416.17 KLO11870.1 - 1.6e-26 92.8 0.0 2e-26 92.5 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S13/S18 FbpA PF05833.6 KLO11870.1 - 8.5e-05 21.2 0.0 0.00011 20.9 0.0 1.3 1 1 0 1 1 1 1 Fibronectin-binding protein A N-terminus (FbpA) FAM70 PF14967.1 KLO11870.1 - 0.041 13.0 1.2 0.05 12.7 0.9 1.1 1 0 0 1 1 1 0 FAM70 protein IMS_HHH PF11798.3 KLO11870.1 - 0.055 13.5 0.0 0.17 12.0 0.0 1.8 2 0 0 2 2 2 0 IMS family HHH motif Pol_alpha_B_N PF08418.5 KLO11870.1 - 0.057 12.9 3.0 0.066 12.7 2.1 1.2 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal Herpes_capsid PF06112.6 KLO11870.1 - 0.58 10.2 7.6 0.88 9.6 5.3 1.3 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein XAP5 PF04921.9 KLO11871.1 - 3.5e-93 311.5 1.7 3.5e-93 311.5 1.2 2.2 1 1 1 2 2 2 1 XAP5, circadian clock regulator DUF4407 PF14362.1 KLO11871.1 - 5.2 5.9 17.4 3.1 6.6 8.9 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) JmjC PF02373.17 KLO11872.1 - 7.7e-10 39.0 0.0 3.2e-09 37.0 0.0 2.1 1 1 1 2 2 2 1 JmjC domain, hydroxylase OrfB_Zn_ribbon PF07282.6 KLO11872.1 - 0.0038 16.8 0.3 0.014 15.0 0.2 1.9 1 0 0 1 1 1 1 Putative transposase DNA-binding domain zf-C5HC2 PF02928.11 KLO11872.1 - 0.13 12.3 5.0 0.33 11.0 3.5 1.7 1 0 0 1 1 1 0 C5HC2 zinc finger zf-C3HC4_3 PF13920.1 KLO11873.1 - 0.0019 17.8 6.4 0.031 13.9 1.8 2.2 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KLO11873.1 - 0.002 17.8 5.3 0.032 13.9 0.7 2.3 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 KLO11873.1 - 0.024 14.6 4.6 0.19 11.7 0.6 2.3 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-Di19 PF05605.7 KLO11873.1 - 0.027 14.5 0.3 2.7 8.2 0.0 2.3 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-RING_2 PF13639.1 KLO11873.1 - 0.03 14.1 8.7 0.3 10.9 5.7 2.1 1 1 1 2 2 2 0 Ring finger domain zf-C3HC4 PF00097.20 KLO11873.1 - 0.036 13.7 6.3 0.19 11.4 1.9 2.4 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-P11 PF03854.9 KLO11873.1 - 0.057 12.8 2.6 0.19 11.2 0.2 2.2 2 1 0 2 2 2 0 P-11 zinc finger Stc1 PF12898.2 KLO11873.1 - 0.1 12.6 5.6 3.4 7.8 0.1 2.1 2 0 0 2 2 2 0 Stc1 domain Pput2613-deam PF14427.1 KLO11873.1 - 0.14 11.8 0.4 0.14 11.8 0.3 1.9 1 1 1 2 2 2 0 Pput_2613-like deaminase zf-RING_6 PF14835.1 KLO11873.1 - 0.14 11.9 0.6 2 8.2 0.0 2.1 2 0 0 2 2 2 0 zf-RING of BARD1-type protein zf-RING_4 PF14570.1 KLO11873.1 - 0.17 11.4 5.0 1.2 8.8 0.6 2.3 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain DnaJ_CXXCXGXG PF00684.14 KLO11873.1 - 0.87 9.6 8.6 8.1 6.5 5.8 2.3 1 1 0 1 1 1 0 DnaJ central domain Prim_Zn_Ribbon PF08273.7 KLO11873.1 - 0.93 9.6 0.2 0.93 9.6 0.1 3.0 3 0 0 3 3 3 0 Zinc-binding domain of primase-helicase Lar_restr_allev PF14354.1 KLO11873.1 - 1.5 9.1 7.4 1.4 9.2 0.1 2.6 1 1 1 2 2 2 0 Restriction alleviation protein Lar zf-TFIIB PF13453.1 KLO11873.1 - 2.2 7.5 8.6 12 5.2 0.1 3.2 3 1 0 3 3 3 0 Transcription factor zinc-finger DZR PF12773.2 KLO11873.1 - 3.6 7.4 8.8 39 4.1 6.1 2.3 1 1 0 1 1 1 0 Double zinc ribbon FdhE PF04216.7 KLO11873.1 - 4.6 6.8 8.5 16 5.1 5.9 1.7 1 1 0 1 1 1 0 Protein involved in formate dehydrogenase formation TF_Zn_Ribbon PF08271.7 KLO11873.1 - 5.7 6.3 10.2 0.31 10.4 0.4 2.6 2 1 0 2 2 2 0 TFIIB zinc-binding zinc-ribbons_6 PF07191.7 KLO11873.1 - 7.1 6.5 7.2 1.9 8.3 1.3 2.3 1 1 1 2 2 2 0 zinc-ribbons KOW PF00467.24 KLO11874.1 - 1.8e-10 40.0 1.8 1.8e-10 40.0 1.2 1.9 2 0 0 2 2 2 1 KOW motif Cut12 PF11500.3 KLO11874.1 - 0.14 11.8 0.7 0.16 11.6 0.0 1.6 2 0 0 2 2 2 0 Spindle pole body formation-associated protein Rer1 PF03248.8 KLO11875.1 - 0.078 12.5 0.1 0.078 12.5 0.1 1.7 2 0 0 2 2 2 0 Rer1 family UPF0104 PF03706.8 KLO11876.1 - 0.0031 16.8 0.2 0.0031 16.8 0.2 1.7 2 1 0 2 2 2 1 Uncharacterised protein family (UPF0104) XK-related PF09815.4 KLO11876.1 - 0.018 14.0 0.4 0.018 14.0 0.3 1.9 2 0 0 2 2 2 0 XK-related protein PIRT PF15099.1 KLO11876.1 - 0.24 10.6 2.2 0.51 9.5 0.0 2.5 2 1 0 2 2 2 0 Phosphoinositide-interacting protein family Y_phosphatase3 PF13350.1 KLO11877.1 - 1e-41 142.9 0.0 1.4e-41 142.5 0.0 1.2 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3C PF13348.1 KLO11877.1 - 5.4e-10 39.2 0.0 1.9e-09 37.5 0.0 2.0 2 0 0 2 2 2 1 Tyrosine phosphatase family C-terminal region Y_phosphatase2 PF03162.8 KLO11877.1 - 1.4e-05 24.4 0.0 2.5e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase PF00102.22 KLO11877.1 - 0.00033 20.0 0.0 0.00049 19.5 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Myotub-related PF06602.9 KLO11877.1 - 0.0021 16.9 0.0 0.003 16.3 0.0 1.2 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain DSPc PF00782.15 KLO11877.1 - 0.023 14.2 0.0 0.044 13.3 0.0 1.4 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain Adeno_shaft PF00608.12 KLO11880.1 - 0.15 11.6 2.7 8.7 6.1 0.0 4.1 3 1 0 3 3 3 0 Adenoviral fibre protein (repeat/shaft region) Lamprin PF06403.6 KLO11880.1 - 2.2 8.0 12.1 6.7e+02 -0.1 8.4 2.8 1 1 0 1 1 1 0 Lamprin PfUIS3 PF11567.3 KLO11882.1 - 0.0023 18.0 0.2 0.0039 17.3 0.1 1.3 1 0 0 1 1 1 1 Plasmodium falciparum UIS3 membrane protein Lon_2 PF13337.1 KLO11882.1 - 0.0033 15.8 0.1 0.0046 15.3 0.1 1.1 1 0 0 1 1 1 1 Putative ATP-dependent Lon protease DED PF01335.16 KLO11882.1 - 0.023 14.8 0.7 0.04 14.0 0.5 1.4 1 0 0 1 1 1 0 Death effector domain FDX-ACB PF03147.9 KLO11882.1 - 0.092 12.9 0.1 0.18 12.0 0.1 1.4 1 0 0 1 1 1 0 Ferredoxin-fold anticodon binding domain DUF4315 PF14193.1 KLO11883.1 - 0.018 14.9 1.2 0.049 13.5 0.9 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4315) DUF837 PF05769.6 KLO11884.1 - 0.0039 16.7 0.5 0.0062 16.0 0.4 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF837) KxDL PF10241.4 KLO11884.1 - 0.015 15.1 0.9 0.025 14.4 0.6 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein LEA_2 PF03168.8 KLO11885.1 - 4.7e-08 33.3 0.0 8.6e-08 32.4 0.0 1.5 1 0 0 1 1 1 1 Late embryogenesis abundant protein Vac7 PF12751.2 KLO11885.1 - 0.00036 19.5 0.0 0.00047 19.1 0.0 1.1 1 0 0 1 1 1 1 Vacuolar segregation subunit 7 DUF1356 PF07092.7 KLO11885.1 - 0.00042 19.5 2.3 0.00057 19.1 1.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1356) Sen15 PF09631.5 KLO11886.1 - 1.1e-18 67.3 0.0 1.4e-18 66.9 0.0 1.1 1 0 0 1 1 1 1 Sen15 protein UFD1 PF03152.9 KLO11887.1 - 5.2e-65 217.8 0.0 6.7e-65 217.5 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin fusion degradation protein UFD1 CDC48_2 PF02933.12 KLO11887.1 - 0.0035 16.9 0.0 0.12 12.0 0.0 2.4 1 1 1 2 2 2 1 Cell division protein 48 (CDC48), domain 2 Cpn60_TCP1 PF00118.19 KLO11888.1 - 2.4e-140 468.4 12.1 2.6e-140 468.2 8.4 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family ThiF PF00899.16 KLO11889.1 - 3e-39 133.9 0.1 8.1e-39 132.5 0.0 1.7 2 0 0 2 2 2 1 ThiF family E2_bind PF08825.5 KLO11889.1 - 2.4e-25 88.0 0.4 4.4e-25 87.2 0.3 1.4 1 0 0 1 1 1 1 E2 binding domain UBACT PF02134.16 KLO11889.1 - 1.1e-24 85.7 0.3 2e-24 84.9 0.2 1.4 1 0 0 1 1 1 1 Repeat in ubiquitin-activating (UBA) protein UBA_e1_thiolCys PF10585.4 KLO11889.1 - 5.8e-15 54.4 3.3 5.8e-15 54.4 2.3 1.8 2 0 0 2 2 2 1 Ubiquitin-activating enzyme active site MoeZ_MoeB PF05237.8 KLO11889.1 - 0.00055 19.4 0.0 0.0013 18.2 0.0 1.6 1 0 0 1 1 1 1 MoeZ/MoeB domain Shikimate_DH PF01488.15 KLO11889.1 - 0.0016 18.5 0.0 0.0031 17.6 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Vint PF14623.1 KLO11889.1 - 0.033 13.6 0.0 0.063 12.7 0.0 1.4 1 0 0 1 1 1 0 Hint-domain Pyr_redox PF00070.22 KLO11889.1 - 0.062 13.7 0.1 0.12 12.7 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase UBA_e1_C PF09358.5 KLO11889.1 - 0.066 13.3 0.0 0.13 12.4 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin-activating enzyme e1 C-terminal domain USP7_ICP0_bdg PF12436.3 KLO11889.1 - 0.11 11.6 0.0 0.18 11.0 0.0 1.2 1 0 0 1 1 1 0 ICP0-binding domain of Ubiquitin-specific protease 7 ApbA PF02558.11 KLO11889.1 - 0.13 11.6 0.0 0.27 10.6 0.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Ecm33 PF12454.3 KLO11889.1 - 0.3 10.9 3.1 0.63 9.9 2.1 1.5 1 0 0 1 1 1 0 GPI-anchored cell wall organization protein Mito_carr PF00153.22 KLO11890.1 - 2.5e-46 155.3 0.7 1e-15 57.1 0.0 3.6 3 1 0 3 3 3 3 Mitochondrial carrier protein Ribosomal_S28e PF01200.13 KLO11891.1 - 1.4e-30 104.7 3.1 1.5e-30 104.6 2.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S28e RRM_1 PF00076.17 KLO11892.1 - 1.6e-05 24.4 0.0 7.8e-05 22.2 0.0 2.0 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCCH PF00642.19 KLO11892.1 - 0.0013 18.3 1.6 0.0033 17.0 1.1 1.7 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) RRM_5 PF13893.1 KLO11892.1 - 0.0037 17.0 0.0 0.15 11.9 0.0 2.4 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCCH_2 PF14608.1 KLO11892.1 - 0.15 12.1 1.4 0.34 10.9 1.0 1.7 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type RRM_6 PF14259.1 KLO11892.1 - 0.18 11.7 0.4 4.4 7.3 0.1 2.8 2 1 0 2 2 2 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) FYVE PF01363.16 KLO11892.1 - 0.53 10.2 6.0 0.088 12.7 1.6 1.9 2 1 0 2 2 2 0 FYVE zinc finger Cript PF10235.4 KLO11892.1 - 5.1 7.5 9.1 0.84 10.0 0.4 2.7 3 0 0 3 3 3 0 Microtubule-associated protein CRIPT LEA_2 PF03168.8 KLO11893.1 - 2.2e-09 37.5 0.0 4.3e-09 36.6 0.0 1.6 1 0 0 1 1 1 1 Late embryogenesis abundant protein DUF4251 PF14059.1 KLO11893.1 - 0.043 13.6 1.6 0.22 11.3 1.1 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4251) DUF1356 PF07092.7 KLO11893.1 - 0.05 12.7 0.7 0.071 12.2 0.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1356) Vac7 PF12751.2 KLO11893.1 - 0.19 10.5 0.1 0.35 9.6 0.1 1.3 1 0 0 1 1 1 0 Vacuolar segregation subunit 7 Rrn6 PF10214.4 KLO11894.1 - 9.2e-17 60.4 2.3 4.8e-08 31.5 0.4 3.2 3 0 0 3 3 3 3 RNA polymerase I-specific transcription-initiation factor NPR2 PF06218.6 KLO11895.1 - 4.9e-111 371.4 0.0 1.1e-94 317.5 0.0 2.5 1 1 1 2 2 2 2 Nitrogen permease regulator 2 NPR3 PF03666.8 KLO11895.1 - 3.7 5.9 8.9 1.3 7.4 0.1 2.6 3 0 0 3 3 3 0 Nitrogen Permease regulator of amino acid transport activity 3 TYW3 PF02676.9 KLO11896.1 - 0.0067 15.5 0.1 0.0074 15.4 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase TYW3 Birna_VP4 PF01768.11 KLO11896.1 - 0.15 11.1 0.0 0.17 10.9 0.0 1.0 1 0 0 1 1 1 0 Birnavirus VP4 protein zf-FPG_IleRS PF06827.9 KLO11897.1 - 0.4 10.3 9.4 0.67 9.6 6.5 1.4 1 0 0 1 1 1 0 Zinc finger found in FPG and IleRS Zn_clus PF00172.13 KLO11897.1 - 0.57 10.1 13.9 3.7 7.5 9.6 2.0 1 1 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Zn_clus PF00172.13 KLO11898.1 - 2.5e-06 27.2 6.9 3.3e-06 26.9 4.8 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Clusterin PF01093.12 KLO11898.1 - 0.082 11.6 0.1 0.09 11.5 0.0 1.0 1 0 0 1 1 1 0 Clusterin RTC PF01137.16 KLO11899.1 - 3.3e-68 228.8 0.0 4.1e-68 228.5 0.0 1.0 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase RTC_insert PF05189.8 KLO11899.1 - 1.3e-29 102.1 0.0 2e-29 101.6 0.0 1.3 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase (RTC), insert domain DUF3759 PF12585.3 KLO11900.1 - 8.6e-05 22.3 0.1 0.00013 21.7 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3759) SOBP PF15279.1 KLO11905.1 - 8.7 6.6 11.1 13 6.1 7.7 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein DUF3759 PF12585.3 KLO11906.1 - 2.3e-05 24.1 0.0 3.5e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3759) NmrA PF05368.8 KLO11907.1 - 2.5e-34 118.5 0.0 3.5e-34 118.0 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 KLO11907.1 - 1.3e-10 41.5 0.1 2.1e-10 40.9 0.1 1.5 1 1 0 1 1 1 1 NADH(P)-binding Saccharop_dh PF03435.13 KLO11907.1 - 5.4e-06 25.6 0.0 9e-06 24.8 0.0 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase KR PF08659.5 KLO11907.1 - 0.00013 21.6 0.1 0.0002 21.1 0.0 1.2 1 0 0 1 1 1 1 KR domain adh_short PF00106.20 KLO11907.1 - 0.00022 21.1 0.1 0.00033 20.6 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase Epimerase PF01370.16 KLO11907.1 - 0.00042 19.8 0.0 0.0024 17.3 0.0 2.2 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Semialdhyde_dh PF01118.19 KLO11907.1 - 0.0067 16.7 0.1 0.012 15.9 0.0 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain 3Beta_HSD PF01073.14 KLO11907.1 - 0.011 14.5 0.0 0.016 13.9 0.0 1.3 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family TrkA_N PF02254.13 KLO11907.1 - 0.013 15.5 0.0 0.025 14.5 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain F420_oxidored PF03807.12 KLO11907.1 - 0.018 15.4 0.0 0.055 13.9 0.0 1.9 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent NAD_binding_7 PF13241.1 KLO11907.1 - 0.026 14.7 0.2 0.22 11.7 0.0 2.2 2 1 0 2 2 2 0 Putative NAD(P)-binding Shikimate_DH PF01488.15 KLO11907.1 - 0.03 14.4 0.0 0.048 13.7 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase NmrA PF05368.8 KLO11908.1 - 1.3e-35 122.7 0.0 1.8e-35 122.2 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 KLO11908.1 - 4.3e-10 39.8 0.3 7.3e-10 39.1 0.2 1.5 1 1 0 1 1 1 1 NADH(P)-binding Saccharop_dh PF03435.13 KLO11908.1 - 8.6e-05 21.6 0.1 0.00014 20.9 0.0 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase adh_short PF00106.20 KLO11908.1 - 0.0012 18.7 0.2 0.0017 18.2 0.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KLO11908.1 - 0.0013 18.4 0.0 0.0019 17.9 0.0 1.3 1 0 0 1 1 1 1 KR domain 3Beta_HSD PF01073.14 KLO11908.1 - 0.0023 16.7 0.0 0.0044 15.7 0.0 1.5 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 KLO11908.1 - 0.0036 16.7 0.0 0.017 14.5 0.0 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family TrkA_N PF02254.13 KLO11908.1 - 0.01 15.8 0.0 0.023 14.6 0.0 1.6 1 0 0 1 1 1 0 TrkA-N domain DapB_N PF01113.15 KLO11908.1 - 0.013 15.4 0.4 0.051 13.4 0.2 1.9 1 1 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Semialdhyde_dh PF01118.19 KLO11908.1 - 0.015 15.5 0.0 0.026 14.8 0.0 1.4 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain F420_oxidored PF03807.12 KLO11908.1 - 0.064 13.6 0.1 0.17 12.2 0.0 1.8 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent DUF3889 PF13028.1 KLO11910.1 - 0.15 11.7 0.4 0.33 10.6 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3889) Sen15 PF09631.5 KLO11916.1 - 3.9e-17 62.3 0.0 5.1e-17 61.9 0.0 1.1 1 0 0 1 1 1 1 Sen15 protein NmrA PF05368.8 KLO11918.1 - 2.6e-37 128.2 0.0 3.7e-37 127.8 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 KLO11918.1 - 5.8e-11 42.7 0.1 9.8e-11 41.9 0.1 1.4 1 0 0 1 1 1 1 NADH(P)-binding Saccharop_dh PF03435.13 KLO11918.1 - 5.5e-07 28.9 0.4 1e-06 28.0 0.1 1.5 2 0 0 2 2 2 1 Saccharopine dehydrogenase KR PF08659.5 KLO11918.1 - 0.00012 21.8 0.0 0.00018 21.2 0.0 1.3 1 0 0 1 1 1 1 KR domain adh_short PF00106.20 KLO11918.1 - 0.00066 19.6 0.1 0.0013 18.6 0.0 1.6 2 0 0 2 2 2 1 short chain dehydrogenase Epimerase PF01370.16 KLO11918.1 - 0.0015 18.0 0.1 0.0059 16.0 0.1 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family TrkA_N PF02254.13 KLO11918.1 - 0.011 15.7 0.1 0.021 14.8 0.1 1.5 1 0 0 1 1 1 0 TrkA-N domain 3Beta_HSD PF01073.14 KLO11918.1 - 0.012 14.3 0.1 0.018 13.7 0.1 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Shikimate_DH PF01488.15 KLO11918.1 - 0.013 15.5 0.0 0.024 14.7 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase F420_oxidored PF03807.12 KLO11918.1 - 0.06 13.7 0.0 0.13 12.6 0.0 1.7 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Pkinase PF00069.20 KLO11919.1 - 1.4e-37 129.2 0.0 2.4e-37 128.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KLO11919.1 - 1.5e-37 129.1 0.0 2.1e-37 128.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KLO11919.1 - 0.00079 18.4 0.0 0.0026 16.7 0.0 1.7 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 KLO11919.1 - 0.031 14.0 0.0 0.059 13.0 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family NmrA PF05368.8 KLO11922.1 - 2.5e-31 108.7 0.0 3.4e-31 108.3 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 KLO11922.1 - 9.1e-09 35.5 0.3 1.8e-08 34.6 0.2 1.7 1 1 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 KLO11922.1 - 0.00077 18.2 0.0 0.0012 17.5 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family F420_oxidored PF03807.12 KLO11922.1 - 0.003 17.9 0.0 0.014 15.7 0.0 2.1 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent Epimerase PF01370.16 KLO11922.1 - 0.0037 16.7 0.0 0.0057 16.1 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Semialdhyde_dh PF01118.19 KLO11922.1 - 0.007 16.6 0.0 0.012 15.9 0.0 1.3 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain adh_short PF00106.20 KLO11922.1 - 0.016 15.1 0.1 0.027 14.3 0.0 1.4 1 0 0 1 1 1 0 short chain dehydrogenase KR PF08659.5 KLO11922.1 - 0.032 13.8 0.0 0.055 13.1 0.0 1.4 1 0 0 1 1 1 0 KR domain DapB_N PF01113.15 KLO11922.1 - 0.14 12.0 0.0 0.25 11.2 0.0 1.5 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Dna2 PF08696.6 KLO11924.1 - 6.9e-58 195.3 0.0 1.2e-57 194.6 0.0 1.4 1 0 0 1 1 1 1 DNA replication factor Dna2 AAA_12 PF13087.1 KLO11924.1 - 7.2e-51 172.4 0.0 1.1e-50 171.7 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 KLO11924.1 - 8e-19 68.1 0.0 2e-18 66.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain PDDEXK_1 PF12705.2 KLO11924.1 - 1.4e-09 37.7 0.0 4.2e-09 36.1 0.0 1.8 2 0 0 2 2 2 1 PD-(D/E)XK nuclease superfamily AAA_30 PF13604.1 KLO11924.1 - 3.9e-08 33.1 0.0 7.1e-08 32.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 KLO11924.1 - 1.2e-07 31.4 0.2 3.7e-07 29.8 0.0 1.9 2 0 0 2 2 2 1 Part of AAA domain Cas_Cas4 PF01930.12 KLO11924.1 - 0.00013 21.9 0.2 0.00094 19.1 0.0 2.4 2 0 0 2 2 2 1 Domain of unknown function DUF83 Viral_helicase1 PF01443.13 KLO11924.1 - 0.00096 18.7 0.0 0.15 11.5 0.0 2.5 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase MobB PF03205.9 KLO11924.1 - 0.00099 18.8 0.2 0.0022 17.7 0.1 1.5 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_16 PF13191.1 KLO11924.1 - 0.0033 17.4 0.0 0.013 15.4 0.0 2.1 1 0 0 1 1 1 1 AAA ATPase domain UvrD-helicase PF00580.16 KLO11924.1 - 0.0065 15.8 0.1 0.014 14.7 0.0 1.6 1 0 0 1 1 1 1 UvrD/REP helicase N-terminal domain SRP54 PF00448.17 KLO11924.1 - 0.011 15.2 0.1 0.019 14.3 0.1 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA PF00004.24 KLO11924.1 - 0.012 15.8 0.0 0.034 14.3 0.0 1.8 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) UvrD_C_2 PF13538.1 KLO11924.1 - 0.025 14.7 0.0 0.065 13.3 0.0 1.7 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain AAA_22 PF13401.1 KLO11924.1 - 0.045 13.9 0.1 0.19 11.9 0.1 2.1 1 1 0 1 1 1 0 AAA domain Helicase_RecD PF05127.9 KLO11924.1 - 0.047 13.3 0.0 0.097 12.3 0.0 1.5 1 0 0 1 1 1 0 Helicase Miro PF08477.8 KLO11924.1 - 0.055 13.9 0.0 0.14 12.7 0.0 1.6 1 0 0 1 1 1 0 Miro-like protein ArgK PF03308.11 KLO11924.1 - 0.056 12.2 0.0 0.11 11.3 0.0 1.3 1 0 0 1 1 1 0 ArgK protein NTPase_1 PF03266.10 KLO11924.1 - 0.09 12.4 0.3 0.19 11.4 0.2 1.5 1 0 0 1 1 1 0 NTPase ThiF PF00899.16 KLO11925.1 - 0.00014 21.7 0.0 0.0003 20.6 0.0 1.6 1 0 0 1 1 1 1 ThiF family Rad17 PF03215.10 KLO11926.1 - 7.3e-61 206.4 0.0 2.2e-59 201.5 0.0 2.0 1 1 0 1 1 1 1 Rad17 cell cycle checkpoint protein AAA PF00004.24 KLO11926.1 - 0.0078 16.4 0.0 0.032 14.4 0.0 2.0 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) zf-C2H2_4 PF13894.1 KLO11929.1 - 1.5e-05 25.0 11.8 0.014 15.7 0.6 3.5 4 0 0 4 4 4 2 C2H2-type zinc finger zf-C2H2 PF00096.21 KLO11929.1 - 0.00013 22.0 15.5 0.0016 18.6 2.3 3.9 4 0 0 4 4 4 2 Zinc finger, C2H2 type zf-met PF12874.2 KLO11929.1 - 0.16 12.2 1.6 14 6.0 0.0 2.6 2 0 0 2 2 2 0 Zinc-finger of C2H2 type KOW PF00467.24 KLO11931.1 - 0.11 12.2 0.0 0.27 11.0 0.0 1.6 1 0 0 1 1 1 0 KOW motif NmrA PF05368.8 KLO11933.1 - 1.5e-35 122.5 0.0 1.9e-35 122.1 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 KLO11933.1 - 5.7e-09 36.2 1.0 2.5e-08 34.1 0.7 1.9 1 1 0 1 1 1 1 NADH(P)-binding KR PF08659.5 KLO11933.1 - 7.8e-05 22.4 0.0 0.00013 21.7 0.0 1.2 1 0 0 1 1 1 1 KR domain Saccharop_dh PF03435.13 KLO11933.1 - 0.00084 18.4 0.0 0.0013 17.7 0.0 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase adh_short PF00106.20 KLO11933.1 - 0.004 17.0 0.2 0.0068 16.3 0.1 1.4 1 0 0 1 1 1 1 short chain dehydrogenase Epimerase PF01370.16 KLO11933.1 - 0.007 15.8 0.0 0.011 15.1 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Semialdhyde_dh PF01118.19 KLO11933.1 - 0.012 15.9 0.1 0.033 14.5 0.0 1.7 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain 3Beta_HSD PF01073.14 KLO11933.1 - 0.015 13.9 0.0 0.027 13.1 0.0 1.4 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family DapB_N PF01113.15 KLO11933.1 - 0.068 13.0 0.1 0.14 12.0 0.0 1.6 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus NmrA PF05368.8 KLO11934.1 - 1e-34 119.8 0.0 1.2e-34 119.5 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 KLO11934.1 - 1.2e-10 41.7 1.7 1.6e-10 41.2 1.2 1.3 1 1 0 1 1 1 1 NADH(P)-binding Saccharop_dh PF03435.13 KLO11934.1 - 7.4e-07 28.4 0.4 1.4e-06 27.5 0.2 1.5 2 0 0 2 2 2 1 Saccharopine dehydrogenase KR PF08659.5 KLO11934.1 - 0.00011 21.9 0.2 0.00018 21.2 0.1 1.3 1 0 0 1 1 1 1 KR domain adh_short PF00106.20 KLO11934.1 - 0.0004 20.3 0.4 0.00063 19.6 0.3 1.3 1 0 0 1 1 1 1 short chain dehydrogenase Semialdhyde_dh PF01118.19 KLO11934.1 - 0.0011 19.2 0.2 0.0019 18.4 0.1 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain 3Beta_HSD PF01073.14 KLO11934.1 - 0.01 14.5 0.3 0.018 13.7 0.2 1.4 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 KLO11934.1 - 0.021 14.2 0.1 0.056 12.8 0.1 1.7 2 1 0 2 2 2 0 NAD dependent epimerase/dehydratase family DapB_N PF01113.15 KLO11934.1 - 0.024 14.5 0.3 0.045 13.6 0.2 1.5 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus NmrA PF05368.8 KLO11935.1 - 2.4e-32 112.0 0.0 3.4e-32 111.5 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 KLO11935.1 - 3.3e-09 37.0 0.2 5e-09 36.4 0.2 1.3 1 0 0 1 1 1 1 NADH(P)-binding Saccharop_dh PF03435.13 KLO11935.1 - 9e-06 24.9 0.5 1.4e-05 24.2 0.3 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase KR PF08659.5 KLO11935.1 - 3.5e-05 23.5 0.1 6.8e-05 22.6 0.1 1.5 1 0 0 1 1 1 1 KR domain adh_short PF00106.20 KLO11935.1 - 0.00015 21.7 0.3 0.00024 21.0 0.2 1.3 1 0 0 1 1 1 1 short chain dehydrogenase F420_oxidored PF03807.12 KLO11935.1 - 0.016 15.6 1.6 0.033 14.6 0.2 2.2 2 1 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent Epimerase PF01370.16 KLO11935.1 - 0.018 14.5 0.1 0.049 13.0 0.1 1.8 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 KLO11935.1 - 0.032 12.9 0.2 0.048 12.3 0.1 1.3 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Semialdhyde_dh PF01118.19 KLO11935.1 - 0.044 14.0 0.1 0.076 13.3 0.1 1.4 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain MoCF_biosynth PF00994.19 KLO11935.1 - 0.28 10.5 3.1 0.76 9.1 1.4 2.2 1 1 1 2 2 2 0 Probable molybdopterin binding domain Tetraspannin PF00335.15 KLO11936.1 - 4.9e-10 39.0 9.7 7.7e-10 38.4 6.7 1.3 1 0 0 1 1 1 1 Tetraspanin family Aldo_ket_red PF00248.16 KLO11939.1 - 3.4e-49 167.1 0.0 4.4e-49 166.8 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family IGPS PF00218.16 KLO11940.1 - 5.9e-91 304.0 0.0 6.8e-91 303.8 0.0 1.0 1 0 0 1 1 1 1 Indole-3-glycerol phosphate synthase QRPTase_C PF01729.14 KLO11940.1 - 0.0025 17.3 0.0 0.0049 16.4 0.0 1.4 1 0 0 1 1 1 1 Quinolinate phosphoribosyl transferase, C-terminal domain NanE PF04131.9 KLO11940.1 - 0.026 13.4 0.0 0.05 12.5 0.0 1.4 1 0 0 1 1 1 0 Putative N-acetylmannosamine-6-phosphate epimerase His_biosynth PF00977.16 KLO11940.1 - 0.053 12.7 0.1 0.12 11.5 0.0 1.7 2 0 0 2 2 2 0 Histidine biosynthesis protein NmrA PF05368.8 KLO11941.1 - 2.4e-32 112.0 0.0 3.3e-32 111.6 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 KLO11941.1 - 3.3e-09 37.0 0.2 5.5e-09 36.2 0.2 1.3 1 0 0 1 1 1 1 NADH(P)-binding KR PF08659.5 KLO11941.1 - 7.7e-06 25.6 0.2 1.3e-05 24.9 0.1 1.3 1 0 0 1 1 1 1 KR domain adh_short PF00106.20 KLO11941.1 - 2.3e-05 24.3 0.3 3.9e-05 23.6 0.2 1.3 1 0 0 1 1 1 1 short chain dehydrogenase F420_oxidored PF03807.12 KLO11941.1 - 0.0014 19.0 0.0 0.0032 17.8 0.0 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Semialdhyde_dh PF01118.19 KLO11941.1 - 0.0023 18.2 0.0 0.0044 17.3 0.0 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain NAD_binding_7 PF13241.1 KLO11941.1 - 0.0097 16.1 0.1 0.044 14.0 0.0 2.0 3 0 0 3 3 3 1 Putative NAD(P)-binding 3Beta_HSD PF01073.14 KLO11941.1 - 0.014 14.0 0.0 0.022 13.4 0.0 1.3 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family TrkA_N PF02254.13 KLO11941.1 - 0.083 12.9 0.0 0.18 11.7 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain Shikimate_DH PF01488.15 KLO11941.1 - 0.1 12.7 0.0 0.19 11.8 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Epimerase PF01370.16 KLO11941.1 - 0.13 11.6 0.0 0.21 11.0 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family ATG27 PF09451.5 KLO11942.1 - 2.7e-08 33.3 0.0 4.2e-08 32.7 0.0 1.2 1 0 0 1 1 1 1 Autophagy-related protein 27 CIMR PF00878.13 KLO11942.1 - 0.045 13.5 0.0 0.29 10.8 0.0 2.2 3 0 0 3 3 3 0 Cation-independent mannose-6-phosphate receptor repeat ATG27 PF09451.5 KLO11943.1 - 0.0068 15.6 0.0 0.0071 15.6 0.0 1.2 1 0 0 1 1 1 1 Autophagy-related protein 27 CIMR PF00878.13 KLO11943.1 - 0.035 13.8 0.0 0.05 13.3 0.0 1.2 1 0 0 1 1 1 0 Cation-independent mannose-6-phosphate receptor repeat Totivirus_coat PF05518.6 KLO11950.1 - 1 7.1 4.4 1.6 6.4 3.1 1.2 1 0 0 1 1 1 0 Totivirus coat protein Peptidase_C48 PF02902.14 KLO11951.1 - 3.7e-12 46.3 0.2 6.3e-12 45.5 0.2 1.3 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain Tet_JBP PF12851.2 KLO11953.1 - 3.6e-11 42.6 0.0 9.1e-11 41.3 0.0 1.7 1 0 0 1 1 1 1 Oxygenase domain of the 2OGFeDO superfamily HTH_21 PF13276.1 KLO11955.1 - 0.00014 21.8 0.0 0.0081 16.1 0.0 2.6 2 0 0 2 2 2 2 HTH-like domain Alpha_kinase PF02816.13 KLO11956.1 - 0.0036 16.9 0.0 0.0045 16.6 0.0 1.1 1 0 0 1 1 1 1 Alpha-kinase family GlcNAc_2-epim PF07221.6 KLO11956.1 - 0.11 11.4 0.1 0.15 11.0 0.1 1.3 1 1 0 1 1 1 0 N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase) Dynamin_N PF00350.18 KLO11957.1 - 5.3e-19 68.6 0.3 7e-18 65.0 0.0 2.5 2 0 0 2 2 2 1 Dynamin family MMR_HSR1 PF01926.18 KLO11957.1 - 5.9e-07 29.4 0.0 4.9e-05 23.2 0.0 2.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase ABC_tran PF00005.22 KLO11957.1 - 1.7e-05 25.1 0.5 7.7e-05 23.0 0.0 2.3 1 1 1 2 2 2 1 ABC transporter DUF258 PF03193.11 KLO11957.1 - 6.2e-05 22.2 0.0 0.00044 19.4 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_29 PF13555.1 KLO11957.1 - 0.00024 20.5 0.0 0.00054 19.4 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_22 PF13401.1 KLO11957.1 - 0.00035 20.7 2.3 0.0091 16.1 0.0 3.3 4 1 0 4 4 3 1 AAA domain AAA_23 PF13476.1 KLO11957.1 - 0.00046 20.5 0.3 0.00046 20.5 0.2 2.8 3 1 1 4 4 3 1 AAA domain AAA_16 PF13191.1 KLO11957.1 - 0.00055 19.9 1.4 0.0038 17.2 0.0 3.0 3 2 0 3 3 2 1 AAA ATPase domain NB-ARC PF00931.17 KLO11957.1 - 0.00069 18.5 0.0 0.0012 17.7 0.0 1.3 1 0 0 1 1 1 1 NB-ARC domain AAA_19 PF13245.1 KLO11957.1 - 0.0023 17.6 0.0 1.1 9.0 0.0 2.5 2 0 0 2 2 2 1 Part of AAA domain Arch_ATPase PF01637.13 KLO11957.1 - 0.0027 17.4 0.0 0.007 16.0 0.0 1.7 1 0 0 1 1 1 1 Archaeal ATPase GTP_EFTU PF00009.22 KLO11957.1 - 0.007 15.8 0.0 0.058 12.8 0.0 2.3 3 0 0 3 3 3 1 Elongation factor Tu GTP binding domain T2SE PF00437.15 KLO11957.1 - 0.0073 15.2 0.0 0.013 14.4 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein DUF815 PF05673.8 KLO11957.1 - 0.018 14.0 0.0 0.039 12.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Zeta_toxin PF06414.7 KLO11957.1 - 0.022 13.8 0.0 0.065 12.3 0.0 1.7 1 0 0 1 1 1 0 Zeta toxin KAP_NTPase PF07693.9 KLO11957.1 - 0.028 13.4 0.0 0.041 12.8 0.0 1.7 1 1 0 1 1 1 0 KAP family P-loop domain AAA_17 PF13207.1 KLO11957.1 - 0.029 15.1 0.7 0.2 12.4 0.1 2.9 2 1 0 2 2 2 0 AAA domain AIG1 PF04548.11 KLO11957.1 - 0.029 13.4 0.0 0.075 12.1 0.0 1.6 1 0 0 1 1 1 0 AIG1 family AAA_21 PF13304.1 KLO11957.1 - 0.037 13.9 0.1 0.17 11.7 0.0 2.1 2 0 0 2 2 2 0 AAA domain Miro PF08477.8 KLO11957.1 - 0.039 14.4 0.0 0.13 12.7 0.0 2.0 1 0 0 1 1 1 0 Miro-like protein AAA_15 PF13175.1 KLO11957.1 - 0.041 12.9 0.1 0.077 12.0 0.1 1.5 1 0 0 1 1 1 0 AAA ATPase domain Parvo_NS1 PF01057.12 KLO11957.1 - 0.053 12.3 0.0 0.1 11.4 0.0 1.4 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 FtsK_SpoIIIE PF01580.13 KLO11957.1 - 0.065 12.7 0.0 0.5 9.8 0.0 2.2 2 0 0 2 2 2 0 FtsK/SpoIIIE family IIGP PF05049.8 KLO11957.1 - 0.069 11.9 0.1 0.48 9.1 0.0 2.1 2 1 0 2 2 2 0 Interferon-inducible GTPase (IIGP) AAA_18 PF13238.1 KLO11957.1 - 0.07 13.4 0.0 0.28 11.4 0.0 2.1 2 0 0 2 2 1 0 AAA domain AAA_10 PF12846.2 KLO11957.1 - 0.072 12.5 0.0 0.25 10.7 0.0 1.9 2 0 0 2 2 2 0 AAA-like domain Adeno_IVa2 PF02456.10 KLO11957.1 - 0.073 11.7 0.0 0.13 10.9 0.0 1.4 1 0 0 1 1 1 0 Adenovirus IVa2 protein Septin PF00735.13 KLO11957.1 - 0.081 11.9 0.0 0.19 10.7 0.0 1.7 1 0 0 1 1 1 0 Septin RNA_helicase PF00910.17 KLO11957.1 - 0.12 12.5 0.0 0.46 10.6 0.0 2.1 1 1 0 1 1 1 0 RNA helicase DUF87 PF01935.12 KLO11957.1 - 0.15 11.9 6.6 0.3 10.8 0.0 3.5 4 1 0 4 4 3 0 Domain of unknown function DUF87 Cys_Met_Meta_PP PF01053.15 KLO11958.1 - 3.5e-146 486.4 0.0 4e-146 486.2 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.12 KLO11958.1 - 6.4e-15 55.0 1.0 6.4e-14 51.7 0.2 2.0 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_1_2 PF00155.16 KLO11958.1 - 1.7e-11 43.7 0.1 2.5e-11 43.1 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.14 KLO11958.1 - 2.2e-08 33.2 0.2 4e-08 32.4 0.1 1.3 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.16 KLO11958.1 - 1.2e-06 27.9 0.0 2.5e-06 26.8 0.0 1.7 1 1 0 1 1 1 1 Beta-eliminating lyase Met_gamma_lyase PF06838.6 KLO11958.1 - 0.0042 15.4 0.1 0.0061 14.9 0.0 1.3 1 0 0 1 1 1 1 Methionine gamma-lyase GDC-P PF02347.11 KLO11958.1 - 0.012 14.3 0.0 0.017 13.8 0.0 1.2 1 0 0 1 1 1 0 Glycine cleavage system P-protein Dynamin_N PF00350.18 KLO11959.1 - 1.9e-19 70.1 1.3 3.2e-18 66.1 0.0 3.3 2 1 1 3 3 3 1 Dynamin family MMR_HSR1 PF01926.18 KLO11959.1 - 7.5e-07 29.1 0.2 0.0021 18.0 0.0 3.0 3 0 0 3 3 3 2 50S ribosome-binding GTPase DUF258 PF03193.11 KLO11959.1 - 0.00061 19.0 0.0 0.0016 17.6 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_16 PF13191.1 KLO11959.1 - 0.014 15.4 0.1 0.073 13.0 0.0 2.3 2 0 0 2 2 2 0 AAA ATPase domain AAA_23 PF13476.1 KLO11959.1 - 0.014 15.6 10.2 0.39 11.0 0.3 2.7 2 1 0 2 2 2 0 AAA domain ABC_tran PF00005.22 KLO11959.1 - 0.017 15.4 2.4 0.023 14.9 0.0 2.5 2 1 0 2 2 2 0 ABC transporter AAA_29 PF13555.1 KLO11959.1 - 0.049 13.1 0.0 0.12 11.8 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain Miro PF08477.8 KLO11959.1 - 0.11 13.0 1.5 0.83 10.1 0.0 3.1 3 0 0 3 3 3 0 Miro-like protein Viral_helicase1 PF01443.13 KLO11959.1 - 0.12 11.8 2.1 0.41 10.1 0.0 2.7 3 1 0 3 3 3 0 Viral (Superfamily 1) RNA helicase Peptidase_M36 PF02128.10 KLO11962.1 - 5.9e-116 387.4 2.0 3.5e-93 312.4 2.5 3.0 2 1 0 2 2 2 2 Fungalysin metallopeptidase (M36) FTP PF07504.8 KLO11962.1 - 0.0019 17.6 1.8 0.0043 16.4 0.3 2.2 2 0 0 2 2 2 1 Fungalysin/Thermolysin Propeptide Motif Peptidase_M4_C PF02868.10 KLO11962.1 - 0.011 15.5 0.2 0.028 14.1 0.0 1.7 2 0 0 2 2 2 0 Thermolysin metallopeptidase, alpha-helical domain Peptidase_M48 PF01435.13 KLO11963.1 - 7.7e-45 153.2 0.0 1.1e-44 152.7 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M48 Peptidase_M56 PF05569.6 KLO11963.1 - 0.0099 14.8 0.7 0.037 13.0 0.1 2.0 2 0 0 2 2 2 1 BlaR1 peptidase M56 DUF2268 PF10026.4 KLO11963.1 - 0.46 9.8 3.7 0.41 10.0 0.1 2.1 2 0 0 2 2 2 0 Predicted Zn-dependent protease (DUF2268) REV PF00424.13 KLO11964.1 - 0.35 10.7 4.2 7.6 6.5 0.0 2.8 3 0 0 3 3 3 0 REV protein (anti-repression trans-activator protein) GMC_oxred_N PF00732.14 KLO11965.1 - 1e-61 208.7 0.1 1.5e-61 208.1 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 KLO11965.1 - 9.7e-34 116.7 0.0 1.8e-33 115.8 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.7 KLO11965.1 - 5.1e-05 22.3 0.1 8.8e-05 21.5 0.1 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_binding_2 PF00890.19 KLO11965.1 - 0.00013 20.9 1.1 0.0012 17.7 0.8 2.0 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 KLO11965.1 - 0.0023 16.9 0.6 0.11 11.3 0.1 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 KLO11965.1 - 0.011 15.6 0.1 0.027 14.3 0.0 1.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 KLO11965.1 - 0.067 11.6 0.2 0.12 10.8 0.2 1.3 1 0 0 1 1 1 0 HI0933-like protein Thi4 PF01946.12 KLO11965.1 - 0.067 12.2 0.1 0.13 11.3 0.1 1.5 1 0 0 1 1 1 0 Thi4 family Pyr_redox_3 PF13738.1 KLO11965.1 - 0.089 12.8 0.6 26 4.8 0.1 2.7 2 1 1 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 KLO11965.1 - 0.11 11.6 1.8 0.86 8.6 0.6 2.2 2 0 0 2 2 2 0 FAD dependent oxidoreductase GIDA PF01134.17 KLO11965.1 - 0.15 10.8 0.1 0.98 8.2 0.0 2.0 2 0 0 2 2 2 0 Glucose inhibited division protein A Aldedh PF00171.17 KLO11966.1 - 5e-127 424.0 0.0 5.6e-127 423.8 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 KLO11966.1 - 8.4e-07 28.0 0.0 1.8e-06 26.9 0.0 1.7 1 1 0 1 1 1 1 Acyl-CoA reductase (LuxC) BAR_2 PF10455.4 KLO11967.1 - 2e-51 174.6 0.2 4.3e-51 173.5 0.2 1.5 1 1 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking BAR PF03114.13 KLO11967.1 - 1.7e-13 50.6 0.1 4.3e-13 49.2 0.1 1.6 1 1 0 1 1 1 1 BAR domain Uds1 PF15456.1 KLO11967.1 - 0.0024 17.8 3.1 0.74 9.8 0.0 2.5 2 0 0 2 2 2 2 Up-regulated During Septation Phasin PF05597.6 KLO11967.1 - 0.019 14.7 2.0 0.024 14.3 0.1 2.0 2 0 0 2 2 2 0 Poly(hydroxyalcanoate) granule associated protein (phasin) zf-C4H2 PF10146.4 KLO11967.1 - 0.061 13.3 0.6 0.17 11.9 0.3 1.9 1 1 0 1 1 1 0 Zinc finger-containing protein DPBB_1 PF03330.13 KLO11968.1 - 7.2e-09 35.5 0.2 1.7e-08 34.3 0.1 1.7 1 1 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Barwin PF00967.12 KLO11968.1 - 0.00091 18.8 0.1 0.0012 18.5 0.1 1.2 1 0 0 1 1 1 1 Barwin family DPBB_1 PF03330.13 KLO11969.1 - 4.4e-10 39.4 0.1 8.4e-10 38.5 0.1 1.5 1 1 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Barwin PF00967.12 KLO11969.1 - 0.004 16.8 0.1 0.0049 16.5 0.0 1.2 1 0 0 1 1 1 1 Barwin family DPBB_1 PF03330.13 KLO11970.1 - 7.3e-09 35.5 0.2 1.4e-08 34.5 0.1 1.5 1 1 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Barwin PF00967.12 KLO11970.1 - 0.003 17.2 0.0 0.0042 16.7 0.0 1.2 1 0 0 1 1 1 1 Barwin family DPBB_1 PF03330.13 KLO11971.1 - 2.2e-09 37.1 0.1 3.5e-09 36.5 0.1 1.4 1 1 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Barwin PF00967.12 KLO11971.1 - 7.4e-05 22.4 0.1 0.0001 21.9 0.0 1.2 1 0 0 1 1 1 1 Barwin family Cerato-platanin PF07249.7 KLO11971.1 - 0.1 12.5 0.1 0.15 12.0 0.0 1.3 1 0 0 1 1 1 0 Cerato-platanin DPBB_1 PF03330.13 KLO11972.1 - 1.3e-07 31.4 0.1 3.5e-07 30.1 0.0 1.7 2 1 0 2 2 2 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Barwin PF00967.12 KLO11972.1 - 0.00047 19.8 0.0 0.00061 19.4 0.0 1.1 1 0 0 1 1 1 1 Barwin family Proteasome PF00227.21 KLO11973.1 - 1.9e-46 157.7 0.1 2.4e-46 157.4 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Pr_beta_C PF12465.3 KLO11973.1 - 2.3e-09 36.3 0.2 5.4e-09 35.1 0.1 1.6 1 0 0 1 1 1 1 Proteasome beta subunits C terminal NUDIX_2 PF13869.1 KLO11974.1 - 1.8e-84 281.7 0.0 2e-84 281.6 0.0 1.0 1 0 0 1 1 1 1 Nucleotide hydrolase DUF3808 PF10300.4 KLO11975.1 - 6.5e-85 285.4 0.0 8.9e-85 284.9 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3808) TPR_2 PF07719.12 KLO11975.1 - 7.8e-08 31.6 0.1 0.035 14.0 0.1 5.0 4 1 0 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.1 KLO11975.1 - 5.5e-07 29.4 0.4 0.012 15.5 0.1 3.1 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.1 KLO11975.1 - 9.2e-06 25.2 4.5 0.15 11.7 0.2 4.7 5 0 0 5 5 5 2 TPR repeat Apc3 PF12895.2 KLO11975.1 - 1.2e-05 25.3 0.5 0.0022 18.0 0.0 3.7 3 0 0 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.1 KLO11975.1 - 8.2e-05 22.1 0.7 0.15 11.9 0.1 3.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.1 KLO11975.1 - 0.00025 21.3 2.0 2.6 8.4 0.0 4.3 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_1 PF00515.23 KLO11975.1 - 0.0004 19.8 0.0 0.39 10.4 0.0 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.1 KLO11975.1 - 0.00047 19.7 0.0 0.048 13.4 0.0 3.8 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_14 PF13428.1 KLO11975.1 - 0.00093 19.6 5.3 1.3 9.8 0.2 4.4 3 2 2 5 5 3 1 Tetratricopeptide repeat TPR_16 PF13432.1 KLO11975.1 - 0.0016 19.0 4.9 1.4 9.6 0.1 4.2 5 0 0 5 5 3 2 Tetratricopeptide repeat TPR_6 PF13174.1 KLO11975.1 - 0.013 15.8 1.3 5.3 7.7 0.0 4.8 5 0 0 5 5 3 0 Tetratricopeptide repeat DUF3606 PF12244.3 KLO11975.1 - 0.06 12.9 0.0 0.14 11.7 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3606) DUF2316 PF10078.4 KLO11975.1 - 0.11 12.4 0.1 0.35 10.8 0.1 1.7 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2316) TPR_10 PF13374.1 KLO11975.1 - 0.25 11.3 3.3 0.23 11.4 0.2 2.6 3 0 0 3 3 3 0 Tetratricopeptide repeat DPBB_1 PF03330.13 KLO11976.1 - 3.6e-10 39.7 0.3 6.7e-10 38.8 0.2 1.5 1 1 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Barwin PF00967.12 KLO11976.1 - 0.00087 18.9 0.3 0.0013 18.4 0.2 1.3 1 1 0 1 1 1 1 Barwin family Sulfate_transp PF00916.15 KLO11977.1 - 1.3e-44 152.3 10.4 1.5e-44 152.0 4.3 2.2 1 1 1 2 2 2 1 Sulfate transporter family cNMP_binding PF00027.24 KLO11977.1 - 2e-15 56.3 0.0 4.3e-15 55.2 0.0 1.6 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain STAS PF01740.16 KLO11977.1 - 5.9e-10 38.5 0.0 1.2e-09 37.5 0.0 1.5 1 0 0 1 1 1 1 STAS domain STAS_2 PF13466.1 KLO11977.1 - 0.0029 17.5 0.7 0.057 13.4 0.1 2.6 2 0 0 2 2 2 1 STAS domain RhoGEF PF00621.15 KLO11978.1 - 7.8e-16 58.4 0.0 1.2e-15 57.8 0.0 1.3 1 0 0 1 1 1 1 RhoGEF domain Hydrophobin PF01185.13 KLO11980.1 - 2.3e-11 43.9 11.2 2.9e-11 43.6 7.7 1.1 1 0 0 1 1 1 1 Fungal hydrophobin dsrm PF00035.20 KLO11981.1 - 0.031 14.8 0.1 0.32 11.6 0.0 2.7 2 0 0 2 2 2 0 Double-stranded RNA binding motif Ras PF00071.17 KLO11982.1 - 1.8e-55 186.7 0.1 2.1e-55 186.5 0.1 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KLO11982.1 - 3.3e-18 66.3 0.0 5.1e-18 65.7 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KLO11982.1 - 1.9e-17 63.0 0.1 2.4e-17 62.7 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 KLO11982.1 - 1.3e-08 34.3 0.0 1.6e-08 33.9 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 KLO11982.1 - 1.3e-06 27.9 0.0 2.8e-06 26.9 0.0 1.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 KLO11982.1 - 1.5e-06 28.1 0.0 3.5e-06 26.9 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase G-alpha PF00503.15 KLO11982.1 - 0.0028 16.4 1.0 0.11 11.1 0.2 2.1 1 1 1 2 2 2 1 G-protein alpha subunit Septin PF00735.13 KLO11982.1 - 0.016 14.2 0.0 0.025 13.5 0.0 1.3 1 0 0 1 1 1 0 Septin SRPRB PF09439.5 KLO11982.1 - 0.017 14.3 0.0 0.03 13.5 0.0 1.4 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_16 PF13191.1 KLO11982.1 - 0.018 15.0 0.2 1 9.3 0.0 2.3 1 1 0 2 2 2 0 AAA ATPase domain DUF258 PF03193.11 KLO11982.1 - 0.07 12.3 0.1 0.15 11.2 0.1 1.6 1 1 0 1 1 1 0 Protein of unknown function, DUF258 Dynamin_N PF00350.18 KLO11982.1 - 0.07 12.9 0.0 0.32 10.7 0.0 2.0 2 1 1 3 3 3 0 Dynamin family Arm PF00514.18 KLO11983.1 - 1e-14 53.7 11.4 2.2e-05 24.1 1.4 5.5 4 1 0 4 4 4 4 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 KLO11983.1 - 9.4e-05 22.6 4.6 0.006 16.8 0.3 1.6 1 1 1 2 2 2 2 HEAT repeats HEAT_EZ PF13513.1 KLO11983.1 - 0.00067 20.0 1.0 0.0037 17.7 0.2 2.5 1 1 1 2 2 2 1 HEAT-like repeat HEAT PF02985.17 KLO11983.1 - 0.0024 17.7 0.0 0.81 9.9 0.0 2.7 2 0 0 2 2 2 1 HEAT repeat Proteasom_PSMB PF10508.4 KLO11983.1 - 0.022 13.0 0.1 0.038 12.2 0.0 1.3 1 0 0 1 1 1 0 Proteasome non-ATPase 26S subunit Ribosomal_S21 PF01165.15 KLO11984.1 - 0.25 10.7 4.3 1.3 8.5 0.8 2.4 2 0 0 2 2 2 0 Ribosomal protein S21 Spt5-NGN PF03439.8 KLO11985.1 - 2.2e-08 33.7 0.0 5.2e-08 32.5 0.0 1.7 1 0 0 1 1 1 1 Early transcription elongation factor of RNA pol II, NGN section HrpB2 PF09487.5 KLO11985.1 - 0.025 14.7 0.1 0.053 13.7 0.1 1.5 1 0 0 1 1 1 0 Bacterial type III secretion protein (HrpB2) JmjC PF02373.17 KLO11986.1 - 0.074 13.3 0.0 0.43 10.8 0.0 2.3 2 0 0 2 2 2 0 JmjC domain, hydroxylase AraC_binding PF02311.14 KLO11986.1 - 0.18 11.5 0.0 0.4 10.3 0.0 1.5 1 0 0 1 1 1 0 AraC-like ligand binding domain Pkinase PF00069.20 KLO11987.1 - 0.00018 20.7 0.1 0.00018 20.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain WaaY PF06176.6 KLO11987.1 - 0.00021 20.6 0.0 0.00023 20.4 0.0 1.1 1 0 0 1 1 1 1 Lipopolysaccharide core biosynthesis protein (WaaY) RIO1 PF01163.17 KLO11987.1 - 0.0031 16.8 0.1 0.0045 16.3 0.0 1.3 1 0 0 1 1 1 1 RIO1 family APH PF01636.18 KLO11987.1 - 0.031 13.9 0.7 0.059 13.1 0.5 1.6 1 1 0 1 1 1 0 Phosphotransferase enzyme family DUF881 PF05949.7 KLO11987.1 - 0.032 13.6 0.0 0.051 13.0 0.0 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF881) Glyco_trans_1_4 PF13692.1 KLO11988.1 - 0.019 15.1 0.0 0.041 14.0 0.0 1.5 1 0 0 1 1 1 0 Glycosyl transferases group 1 Fungal_trans PF04082.13 KLO11989.1 - 1.8e-17 63.0 0.2 3.1e-17 62.3 0.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KLO11989.1 - 1.8e-05 24.5 10.3 3.1e-05 23.8 7.1 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Gag_p17 PF00540.13 KLO11989.1 - 0.085 12.6 0.0 0.19 11.5 0.0 1.5 1 0 0 1 1 1 0 gag gene protein p17 (matrix protein) Racemase_4 PF13615.1 KLO11990.1 - 3.5e-18 65.7 0.0 6.9e-18 64.7 0.0 1.5 1 0 0 1 1 1 1 Putative alanine racemase MCM_bind PF09739.4 KLO11990.1 - 2.9e-16 59.1 0.0 9.1e-16 57.5 0.0 1.8 2 0 0 2 2 2 1 Mini-chromosome maintenance replisome factor PGM_PMM_I PF02878.11 KLO11991.1 - 1.6e-38 131.2 0.0 3e-38 130.4 0.0 1.4 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_III PF02880.11 KLO11991.1 - 2.7e-18 66.0 0.0 5e-18 65.1 0.0 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_II PF02879.11 KLO11991.1 - 1.5e-16 60.5 0.0 4.6e-16 59.0 0.0 1.9 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.15 KLO11991.1 - 7.3e-05 22.6 0.1 0.00026 20.9 0.1 1.9 1 1 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain PHD PF00628.24 KLO11992.1 - 3.1e-15 55.5 17.1 1.8e-10 40.3 3.2 2.9 3 0 0 3 3 3 2 PHD-finger zf-PHD-like PF15446.1 KLO11992.1 - 0.00044 19.5 0.6 0.035 13.3 0.2 2.4 2 0 0 2 2 2 1 PHD/FYVE-zinc-finger like domain zf-HC5HC2H PF13771.1 KLO11992.1 - 0.0028 17.7 1.3 0.0028 17.7 0.9 2.1 2 0 0 2 2 2 1 PHD-like zinc-binding domain C1_1 PF00130.17 KLO11992.1 - 0.025 14.3 9.5 0.053 13.2 0.2 2.8 3 0 0 3 3 3 0 Phorbol esters/diacylglycerol binding domain (C1 domain) PHD_2 PF13831.1 KLO11992.1 - 0.028 13.7 0.2 0.028 13.7 0.1 3.7 3 1 0 3 3 3 0 PHD-finger zf-RING-like PF08746.6 KLO11992.1 - 0.13 12.3 8.5 2.5 8.1 0.4 2.7 2 0 0 2 2 2 0 RING-like domain DUF2946 PF11162.3 KLO11992.1 - 0.39 10.9 7.1 0.18 11.9 0.3 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2946) Rubredoxin PF00301.15 KLO11992.1 - 0.49 10.3 8.5 0.87 9.5 0.3 2.8 2 0 0 2 2 2 0 Rubredoxin Prok-RING_1 PF14446.1 KLO11992.1 - 0.7 9.6 11.9 5.3 6.8 0.9 3.7 4 0 0 4 4 4 0 Prokaryotic RING finger family 1 DZR PF12773.2 KLO11992.1 - 2.7 7.8 10.2 37 4.2 0.1 3.1 2 1 1 3 3 3 0 Double zinc ribbon DUF202 PF02656.10 KLO11993.1 - 1.7e-06 28.1 0.2 2.2e-05 24.5 0.0 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF202) Tmemb_185A PF10269.4 KLO11993.1 - 0.0013 18.3 0.3 0.0016 18.1 0.2 1.0 1 0 0 1 1 1 1 Transmembrane Fragile-X-F protein DUF1109 PF06532.6 KLO11993.1 - 0.015 14.7 1.9 0.038 13.3 1.3 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1109) DUF3784 PF12650.2 KLO11993.1 - 0.021 14.7 0.1 0.041 13.8 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3784) PalH PF08733.5 KLO11993.1 - 0.033 13.0 0.3 0.038 12.8 0.2 1.0 1 0 0 1 1 1 0 PalH/RIM21 DUF4405 PF14358.1 KLO11993.1 - 0.92 9.6 5.2 0.61 10.2 1.4 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4405) DUF3955 PF13127.1 KLO11993.1 - 3.7 7.1 6.8 16 5.1 0.7 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3955) YbgT_YccB PF08173.6 KLO11993.1 - 9.3 6.1 7.1 0.45 10.3 0.6 2.0 2 0 0 2 2 2 0 Membrane bound YbgT-like protein PhoD PF09423.5 KLO11994.1 - 7.9e-42 143.3 6.3 2.1e-41 141.9 4.3 1.5 1 1 0 1 1 1 1 PhoD-like phosphatase Myosin_head PF00063.16 KLO11995.1 - 4.9e-241 801.5 0.0 4.9e-241 801.5 0.0 1.4 2 0 0 2 2 2 1 Myosin head (motor domain) DIL PF01843.14 KLO11995.1 - 1.3e-34 118.2 2.8 1.3e-34 118.2 2.0 2.8 3 0 0 3 3 3 1 DIL domain IQ PF00612.22 KLO11995.1 - 7.3e-12 43.8 40.1 0.00094 18.6 1.4 6.9 6 0 0 6 6 6 5 IQ calmodulin-binding motif AAA_22 PF13401.1 KLO11995.1 - 0.0053 16.9 1.0 0.018 15.1 0.0 2.5 2 0 0 2 2 2 1 AAA domain Myosin_N PF02736.14 KLO11995.1 - 0.012 15.2 3.0 0.026 14.1 2.1 1.5 1 0 0 1 1 1 0 Myosin N-terminal SH3-like domain DUF2645 PF10840.3 KLO11995.1 - 0.091 12.9 0.0 0.34 11.1 0.0 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2645) AAA_17 PF13207.1 KLO11995.1 - 0.23 12.2 1.8 2.8 8.7 0.0 3.2 2 1 0 2 2 2 0 AAA domain ABC_tran PF00005.22 KLO11995.1 - 0.99 9.7 5.5 0.87 9.8 0.0 2.6 2 0 0 2 2 2 0 ABC transporter TPR_MLP1_2 PF07926.7 KLO11995.1 - 4.1 7.1 28.6 0.037 13.7 4.3 2.6 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein DUF342 PF03961.8 KLO11995.1 - 9.2 4.5 11.7 18 3.5 8.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF342) COG4 PF08318.7 KLO11996.1 - 1e-55 188.8 0.0 2.4e-55 187.6 0.0 1.7 2 0 0 2 2 2 1 COG4 transport protein Tbf5 PF06331.7 KLO11996.1 - 0.019 14.7 0.4 0.49 10.2 0.0 3.1 3 0 0 3 3 3 0 Transcription factor TFIIH complex subunit Tfb5 Decorin_bind PF02352.10 KLO11996.1 - 0.045 13.7 0.0 0.26 11.2 0.0 2.3 1 0 0 1 1 1 0 Decorin binding protein FlgN PF05130.7 KLO11996.1 - 0.051 13.8 0.8 0.13 12.5 0.1 2.0 2 0 0 2 2 2 0 FlgN protein Snf7 PF03357.16 KLO11997.1 - 2.1e-36 124.8 24.8 8.3e-36 122.9 16.2 1.9 2 0 0 2 2 2 1 Snf7 DUF1824 PF08854.5 KLO11997.1 - 0.25 10.9 2.9 0.52 9.9 0.3 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF1824) YlqD PF11068.3 KLO11997.1 - 0.3 11.1 14.7 0.1 12.6 5.8 2.2 1 1 1 2 2 2 0 YlqD protein COG4 PF08318.7 KLO11997.1 - 0.34 9.6 4.5 0.42 9.3 3.1 1.2 1 0 0 1 1 1 0 COG4 transport protein E2_bind PF08825.5 KLO11997.1 - 0.52 10.1 5.1 9.1 6.1 0.2 2.8 2 1 0 2 2 2 0 E2 binding domain RE_Alw26IDE PF09665.5 KLO11997.1 - 0.53 8.9 7.3 0.35 9.5 0.4 2.0 1 1 1 2 2 2 0 Type II restriction endonuclease (RE_Alw26IDE) Prominin PF05478.6 KLO11997.1 - 6.4 4.1 7.2 5.6 4.3 0.5 2.1 1 1 0 2 2 2 0 Prominin Glyco_hydro_3 PF00933.16 KLO11998.1 - 7.9e-72 241.7 0.0 1.2e-71 241.2 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 KLO11998.1 - 3e-69 232.9 0.0 2.2e-68 230.1 0.0 2.1 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 KLO11998.1 - 1.6e-18 66.4 0.0 3e-18 65.5 0.0 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain PA14 PF07691.7 KLO11998.1 - 5.4e-06 26.1 0.0 1.1e-05 25.1 0.0 1.4 1 0 0 1 1 1 1 PA14 domain PIG-S PF10510.4 KLO11998.1 - 0.16 10.6 0.0 0.25 9.9 0.0 1.2 1 0 0 1 1 1 0 Phosphatidylinositol-glycan biosynthesis class S protein DUF2340 PF10209.4 KLO11999.1 - 1e-38 132.2 1.4 1.2e-38 132.0 0.9 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2340) SAC3 PF12209.3 KLO11999.1 - 0.17 12.0 0.7 4.6 7.4 0.1 2.3 2 0 0 2 2 2 0 Leucine permease transcriptional regulator helical domain Pkinase PF00069.20 KLO12000.1 - 1.1e-56 191.8 0.0 1.6e-56 191.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KLO12000.1 - 1.4e-19 70.2 0.3 2.7e-19 69.2 0.1 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.18 KLO12000.1 - 0.0021 17.8 0.0 0.0042 16.8 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.17 KLO12000.1 - 0.017 14.4 0.2 0.035 13.4 0.1 1.5 1 0 0 1 1 1 0 RIO1 family Choline_kinase PF01633.15 KLO12000.1 - 0.1 12.1 0.3 0.19 11.2 0.2 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase ABC1 PF03109.11 KLO12000.1 - 0.12 12.3 0.1 1.3 8.9 0.0 2.2 2 0 0 2 2 2 0 ABC1 family Kdo PF06293.9 KLO12000.1 - 0.28 10.1 0.1 0.79 8.7 0.0 1.7 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF974 PF06159.8 KLO12001.1 - 1.1e-61 208.4 0.0 1.6e-61 207.9 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF974) V-ATPase_H_N PF03224.9 KLO12002.1 - 2.1e-89 299.7 2.5 3.4e-89 299.0 1.8 1.3 1 0 0 1 1 1 1 V-ATPase subunit H V-ATPase_H_C PF11698.3 KLO12002.1 - 3.7e-42 143.0 0.1 2.1e-41 140.5 0.0 2.1 2 0 0 2 2 2 1 V-ATPase subunit H Arm_2 PF04826.8 KLO12002.1 - 0.00012 21.2 0.1 0.00045 19.4 0.0 2.0 2 0 0 2 2 2 1 Armadillo-like HEAT_2 PF13646.1 KLO12002.1 - 0.00021 21.4 0.1 0.92 9.8 0.0 3.0 3 0 0 3 3 3 2 HEAT repeats DUF2435 PF10363.4 KLO12002.1 - 0.032 14.1 0.1 0.78 9.6 0.0 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF2435) Cnd1 PF12717.2 KLO12002.1 - 0.035 13.9 1.9 2 8.1 0.2 2.8 2 1 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.17 KLO12002.1 - 0.058 13.5 0.2 0.68 10.1 0.0 3.0 3 0 0 3 3 3 0 HEAT repeat DUF2019 PF09450.5 KLO12002.1 - 0.078 12.8 0.4 1.3 8.9 0.0 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF2019) MRP-L46 PF11788.3 KLO12003.1 - 1.5e-19 70.7 1.0 2.7e-19 69.8 0.7 1.5 1 0 0 1 1 1 1 39S mitochondrial ribosomal protein L46 NUDIX PF00293.23 KLO12003.1 - 0.00028 20.5 0.1 0.00071 19.2 0.0 1.7 1 1 0 1 1 1 1 NUDIX domain Endonuclease_NS PF01223.18 KLO12004.1 - 8.8e-52 175.7 0.0 1.1e-51 175.4 0.0 1.1 1 0 0 1 1 1 1 DNA/RNA non-specific endonuclease R3H PF01424.17 KLO12005.1 - 2.8e-12 46.1 0.1 6.3e-12 45.0 0.1 1.6 1 0 0 1 1 1 1 R3H domain RRM_6 PF14259.1 KLO12005.1 - 5.9e-08 32.5 0.0 1e-07 31.7 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 KLO12005.1 - 2.5e-07 30.2 0.0 9.3e-07 28.3 0.0 2.0 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KLO12005.1 - 0.00025 20.8 0.0 0.00045 20.0 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SUZ-C PF12901.2 KLO12005.1 - 0.0014 18.2 1.4 0.005 16.4 1.0 2.0 1 0 0 1 1 1 1 SUZ-C motif EcsC PF12787.2 KLO12005.1 - 0.079 12.3 0.1 0.13 11.6 0.0 1.2 1 0 0 1 1 1 0 EcsC protein family LRR_2 PF07723.8 KLO12006.1 - 0.076 13.5 1.2 0.78 10.3 0.2 2.9 2 0 0 2 2 2 0 Leucine Rich Repeat UQ_con PF00179.21 KLO12009.1 - 2.8e-44 149.9 0.0 3.5e-44 149.6 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 KLO12009.1 - 0.00016 21.5 0.0 0.00022 21.0 0.0 1.4 1 1 0 1 1 1 1 RWD domain UEV PF05743.8 KLO12009.1 - 0.0029 17.3 0.0 0.005 16.5 0.0 1.4 1 1 0 1 1 1 1 UEV domain Prok-E2_B PF14461.1 KLO12009.1 - 0.034 13.9 0.0 0.046 13.4 0.0 1.2 1 0 0 1 1 1 0 Prokaryotic E2 family B EF-hand_4 PF12763.2 KLO12010.1 - 1.6e-32 111.2 0.0 4.4e-13 48.8 0.0 3.4 3 0 0 3 3 3 3 Cytoskeletal-regulatory complex EF hand UBA PF00627.26 KLO12010.1 - 3.7e-08 32.9 0.0 8.2e-08 31.8 0.0 1.5 1 0 0 1 1 1 1 UBA/TS-N domain EF-hand_7 PF13499.1 KLO12010.1 - 1.1e-07 31.9 0.0 0.0026 17.8 0.0 3.5 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_1 PF00036.27 KLO12010.1 - 0.00039 19.5 0.9 1.7 8.1 0.0 4.2 5 0 0 5 5 5 1 EF hand EF-hand_6 PF13405.1 KLO12010.1 - 0.00086 19.0 1.6 12 6.0 0.1 4.4 4 0 0 4 4 4 1 EF-hand domain WEMBL PF05701.6 KLO12010.1 - 0.026 12.9 31.4 0.052 12.0 21.8 1.3 1 0 0 1 1 1 0 Weak chloroplast movement under blue light MMPL PF03176.10 KLO12010.1 - 0.13 10.9 4.0 0.26 9.9 2.8 1.5 1 0 0 1 1 1 0 MMPL family Fib_alpha PF08702.5 KLO12010.1 - 1.1 9.4 12.0 0.048 13.7 0.9 2.4 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family PDEase_II PF02112.10 KLO12011.1 - 4.1e-40 137.7 0.0 6.8e-40 137.0 0.0 1.3 1 0 0 1 1 1 1 cAMP phosphodiesterases class-II Lactamase_B_2 PF12706.2 KLO12011.1 - 1e-11 44.7 0.0 1.8e-11 43.9 0.0 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 KLO12011.1 - 0.0039 16.8 0.2 0.0075 15.9 0.1 1.5 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily NAPRTase PF04095.11 KLO12012.1 - 8e-56 189.0 0.0 9.9e-56 188.7 0.0 1.1 1 0 0 1 1 1 1 Nicotinate phosphoribosyltransferase (NAPRTase) family BIR PF00653.16 KLO12013.1 - 4.7e-37 126.2 1.4 7.5e-20 71.1 0.2 2.1 2 0 0 2 2 2 2 Inhibitor of Apoptosis domain zf-C3HC PF07967.8 KLO12013.1 - 0.006 16.3 0.1 4.4 7.0 0.0 3.0 2 1 0 2 2 2 2 C3HC zinc finger-like WD40 PF00400.27 KLO12014.1 - 1.1e-46 155.0 2.6 1.2e-08 34.4 0.0 6.9 7 0 0 7 7 7 6 WD domain, G-beta repeat Striatin PF08232.7 KLO12014.1 - 7.6e-35 120.1 6.8 7.6e-35 120.1 4.7 4.6 3 2 0 3 3 3 1 Striatin family Nucleoporin_N PF08801.6 KLO12014.1 - 0.00015 20.6 2.0 0.041 12.6 0.0 2.8 3 1 1 4 4 4 2 Nup133 N terminal like Nup160 PF11715.3 KLO12014.1 - 0.024 12.7 0.0 0.078 11.1 0.0 1.8 2 0 0 2 2 2 0 Nucleoporin Nup120/160 Nucleo_P87 PF07267.6 KLO12014.1 - 3.9 6.0 6.3 6.6 5.2 4.4 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 TMA7 PF09072.5 KLO12015.1 - 1e-21 77.1 18.6 1.3e-21 76.7 12.9 1.2 1 0 0 1 1 1 1 Translation machinery associated TMA7 MLIP PF15274.1 KLO12015.1 - 0.07 12.6 0.3 0.082 12.3 0.2 1.0 1 0 0 1 1 1 0 Muscular LMNA-interacting protein Peptidase_S9 PF00326.16 KLO12016.1 - 4e-14 52.3 0.0 6.2e-14 51.7 0.0 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 KLO12016.1 - 7e-14 51.8 0.3 1.4e-13 50.8 0.2 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KLO12016.1 - 4.8e-11 42.9 6.1 1.2e-10 41.7 4.2 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KLO12016.1 - 3.8e-05 23.3 0.2 0.0001 21.9 0.1 1.6 1 1 1 2 2 2 1 alpha/beta hydrolase fold Esterase PF00756.15 KLO12016.1 - 0.004 16.6 0.4 0.0097 15.3 0.1 1.7 2 0 0 2 2 2 1 Putative esterase DLH PF01738.13 KLO12016.1 - 0.073 12.3 0.0 0.17 11.1 0.0 1.5 1 1 0 1 1 1 0 Dienelactone hydrolase family BAAT_C PF08840.6 KLO12016.1 - 0.081 12.6 0.1 0.55 9.8 0.0 2.2 2 1 0 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal LIP PF03583.9 KLO12016.1 - 0.092 11.9 0.1 6.1 5.9 0.0 2.2 2 0 0 2 2 2 0 Secretory lipase Tannase PF07519.6 KLO12016.1 - 0.1 11.3 0.0 0.16 10.6 0.0 1.2 1 0 0 1 1 1 0 Tannase and feruloyl esterase DUF1749 PF08538.5 KLO12016.1 - 0.1 11.4 0.0 0.29 9.9 0.0 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF1749) Mob1_phocein PF03637.12 KLO12017.1 - 2.2e-65 219.5 0.2 2.9e-65 219.2 0.2 1.1 1 0 0 1 1 1 1 Mob1/phocein family SDA1 PF05285.7 KLO12018.1 - 1.3e-70 238.2 46.6 4.6e-38 131.2 5.1 3.1 2 1 1 3 3 3 3 SDA1 NUC130_3NT PF08158.7 KLO12018.1 - 3.5e-17 62.4 0.6 2.6e-16 59.6 0.1 2.4 2 0 0 2 2 2 1 NUC130/3NT domain HOOK PF05622.7 KLO12019.1 - 2.1e-56 191.1 49.9 2.1e-56 191.1 34.6 2.6 1 1 1 2 2 2 2 HOOK protein TPR_MLP1_2 PF07926.7 KLO12019.1 - 0.0019 17.9 10.0 0.0019 17.9 6.9 7.4 5 1 2 7 7 7 3 TPR/MLP1/MLP2-like protein Not1 PF04054.10 KLO12020.1 - 8.7e-117 390.1 0.1 2.1e-116 388.9 0.0 1.7 1 1 0 1 1 1 1 CCR4-Not complex component, Not1 DUF3819 PF12842.2 KLO12020.1 - 1.3e-47 161.1 0.0 3e-47 159.9 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF3819) Alpha-amylase PF00128.19 KLO12021.1 - 1.1e-52 179.3 0.1 2.8e-52 178.0 0.0 1.6 1 1 0 1 1 1 1 Alpha amylase, catalytic domain DUF1966 PF09260.6 KLO12021.1 - 3.9e-14 52.4 0.3 1.1e-13 51.1 0.1 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF1966) Sugar_tr PF00083.19 KLO12022.1 - 1.3e-68 231.6 22.4 2e-68 231.0 15.5 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KLO12022.1 - 2.5e-20 72.4 36.5 2.5e-20 72.4 25.3 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily MFS_2 PF13347.1 KLO12022.1 - 0.00026 19.5 31.4 0.00079 17.9 8.1 3.4 3 1 1 4 4 4 3 MFS/sugar transport protein Atg14 PF10186.4 KLO12023.1 - 2.9 6.7 10.3 4.8 6.0 7.1 1.3 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Pyridoxal_deC PF00282.14 KLO12024.1 - 1.7e-61 207.7 0.0 2.3e-61 207.3 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.14 KLO12024.1 - 1.6e-05 23.8 0.0 2.7e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V Pkinase_Tyr PF07714.12 KLO12025.1 - 7.5e-45 153.0 0.0 1.3e-44 152.1 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 KLO12025.1 - 1.1e-40 139.5 0.0 2e-40 138.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain RasGEF PF00617.14 KLO12025.1 - 6.9e-35 120.4 0.3 1.2e-34 119.6 0.2 1.4 1 0 0 1 1 1 1 RasGEF domain Kinase-like PF14531.1 KLO12025.1 - 0.0028 16.6 0.0 0.0051 15.7 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 KLO12025.1 - 0.0043 16.8 1.4 0.23 11.1 0.1 3.1 2 1 1 3 3 3 1 Phosphotransferase enzyme family Kdo PF06293.9 KLO12025.1 - 0.028 13.4 0.1 0.15 11.1 0.0 2.2 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 KLO12025.1 - 0.12 11.6 0.1 0.31 10.3 0.0 1.6 2 0 0 2 2 2 0 RIO1 family RTC PF01137.16 KLO12026.1 - 8.6e-70 234.0 0.0 1.2e-69 233.6 0.0 1.2 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase RTC_insert PF05189.8 KLO12026.1 - 8.3e-21 73.9 0.1 1.4e-20 73.1 0.0 1.4 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase (RTC), insert domain CDC50 PF03381.10 KLO12027.1 - 8.3e-89 297.4 0.0 1.1e-88 297.0 0.0 1.1 1 0 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family DUF4282 PF14110.1 KLO12027.1 - 0.7 10.1 2.6 1.3 9.2 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4282) DnaJ PF00226.26 KLO12028.1 - 9.3e-25 86.1 1.4 2e-24 85.0 1.0 1.6 1 0 0 1 1 1 1 DnaJ domain CTDII PF01556.13 KLO12028.1 - 1.6e-21 75.9 2.3 6.3e-18 64.4 0.0 2.9 3 0 0 3 3 3 2 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.14 KLO12028.1 - 6.1e-15 55.0 20.5 1e-14 54.3 14.2 1.4 1 0 0 1 1 1 1 DnaJ central domain HypA PF01155.14 KLO12028.1 - 0.0041 16.7 8.9 0.1 12.2 1.1 2.3 2 0 0 2 2 2 2 Hydrogenase expression/synthesis hypA family CN_hydrolase PF00795.17 KLO12029.1 - 4.2e-26 91.4 0.0 6e-26 90.9 0.0 1.2 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase DAGK_cat PF00781.19 KLO12030.1 - 4.1e-16 58.6 0.1 6.3e-16 57.9 0.1 1.3 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain ADK PF00406.17 KLO12031.1 - 4.1e-42 143.5 0.2 8.9e-42 142.5 0.1 1.5 1 1 0 1 1 1 1 Adenylate kinase AAA_18 PF13238.1 KLO12031.1 - 7.9e-10 39.1 0.0 1.5e-09 38.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 KLO12031.1 - 1.8e-08 35.1 0.0 2.9e-08 34.5 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 KLO12031.1 - 0.00019 21.3 0.1 0.0065 16.3 0.0 2.2 1 1 0 1 1 1 1 AAA domain Thymidylate_kin PF02223.12 KLO12031.1 - 0.00034 20.0 2.3 0.022 14.1 1.6 2.1 1 1 0 1 1 1 1 Thymidylate kinase HA2 PF04408.18 KLO12032.1 - 1.1e-18 67.1 0.0 2.9e-18 65.7 0.0 1.7 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.11 KLO12032.1 - 1.2e-17 63.7 0.0 2.3e-17 62.8 0.0 1.4 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.26 KLO12032.1 - 7.3e-13 48.1 0.0 1.5e-12 47.1 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 KLO12032.1 - 0.044 13.2 0.0 0.11 12.0 0.0 1.6 1 0 0 1 1 1 0 DEAD/DEAH box helicase Transposase_21 PF02992.9 KLO12033.1 - 3.3e-08 32.9 0.0 6.7e-08 31.9 0.0 1.5 1 0 0 1 1 1 1 Transposase family tnp2 Nop14 PF04147.7 KLO12033.1 - 0.31 8.8 2.8 0.43 8.4 2.0 1.1 1 0 0 1 1 1 0 Nop14-like family Helicase_C PF00271.26 KLO12034.1 - 2e-15 56.3 0.0 4.7e-15 55.1 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain p450 PF00067.17 KLO12036.1 - 1.8e-70 237.7 0.0 2.5e-70 237.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 MFS_1 PF07690.11 KLO12037.1 - 1.8e-14 53.2 32.1 6.1e-09 35.0 7.4 3.1 1 1 2 3 3 3 3 Major Facilitator Superfamily TMEM141 PF15110.1 KLO12037.1 - 0.025 14.8 0.4 0.57 10.4 0.0 2.5 2 0 0 2 2 2 0 TMEM141 protein family DUF1279 PF06916.8 KLO12037.1 - 0.22 11.8 3.9 15 5.9 0.8 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF1279) F-box-like PF12937.2 KLO12038.1 - 4.1e-07 29.6 2.1 1.2e-06 28.1 1.4 1.9 1 1 0 1 1 1 1 F-box-like F-box-like PF12937.2 KLO12039.1 - 0.00019 21.1 3.4 0.00043 19.9 1.4 2.5 2 1 0 2 2 2 1 F-box-like p450 PF00067.17 KLO12040.1 - 2.5e-69 234.0 0.0 3.2e-69 233.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 MFS_1 PF07690.11 KLO12043.1 - 2.7e-22 78.9 56.5 3.1e-14 52.4 20.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Abhydrolase_6 PF12697.2 KLO12044.1 - 6.9e-15 55.5 0.2 8e-15 55.3 0.2 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KLO12044.1 - 0.0057 16.4 0.0 0.0089 15.7 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family p450 PF00067.17 KLO12046.1 - 1.5e-70 238.0 0.0 1.8e-70 237.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF2721 PF11026.3 KLO12047.1 - 1.5 8.4 6.4 3.2 7.3 1.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2721) Vezatin PF12632.2 KLO12048.1 - 0.12 11.3 2.5 0.27 10.2 1.7 1.6 1 0 0 1 1 1 0 Mysoin-binding motif of peroxisomes DUF368 PF04018.8 KLO12049.1 - 0.28 10.3 8.6 0.11 11.6 3.8 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF368) NfeD PF01957.13 KLO12051.1 - 0.049 13.7 11.6 0.055 13.5 6.2 2.3 2 1 0 2 2 2 0 NfeD-like C-terminal, partner-binding LSR PF05624.9 KLO12051.1 - 0.46 10.2 0.1 0.46 10.2 0.0 3.4 3 0 0 3 3 3 0 Lipolysis stimulated receptor (LSR) DUF4383 PF14325.1 KLO12056.1 - 0.2 11.6 0.1 0.2 11.6 0.0 2.8 2 1 0 2 2 2 0 Domain of unknown function (DUF4383) DUF443 PF04276.7 KLO12056.1 - 3 7.2 13.7 0.075 12.4 4.5 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF443) Col_cuticle_N PF01484.12 KLO12057.1 - 1.5 8.5 8.4 0.2 11.3 0.2 2.9 2 0 0 2 2 2 0 Nematode cuticle collagen N-terminal domain FixH PF05751.6 KLO12058.1 - 0.3 10.8 3.8 0.51 10.1 2.6 1.4 1 0 0 1 1 1 0 FixH DUF443 PF04276.7 KLO12059.1 - 0.0029 17.0 4.5 0.0053 16.2 3.2 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF443) DUF2418 PF10332.4 KLO12060.1 - 0.16 12.2 6.8 0.42 10.9 0.6 3.2 3 1 0 3 3 3 0 Protein of unknown function (DUF2418) FA_desaturase PF00487.19 KLO12060.1 - 5.6 6.3 10.8 0.23 10.8 1.6 2.3 1 1 1 2 2 2 0 Fatty acid desaturase Flocculin_t3 PF13928.1 KLO12061.1 - 0.068 13.3 0.8 0.12 12.5 0.6 1.4 1 0 0 1 1 1 0 Flocculin type 3 repeat NAD_binding_10 PF13460.1 KLO12062.1 - 4e-14 53.0 0.0 8.3e-12 45.4 0.0 2.1 1 1 0 1 1 1 1 NADH(P)-binding adh_short PF00106.20 KLO12062.1 - 2.6e-07 30.6 0.0 5e-07 29.7 0.0 1.5 1 0 0 1 1 1 1 short chain dehydrogenase Epimerase PF01370.16 KLO12062.1 - 5.8e-05 22.6 0.0 0.00011 21.7 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short_C2 PF13561.1 KLO12062.1 - 7.5e-05 22.6 0.0 0.00012 21.9 0.0 1.4 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NmrA PF05368.8 KLO12062.1 - 0.0007 18.9 0.0 0.0021 17.3 0.0 1.7 2 0 0 2 2 2 1 NmrA-like family KR PF08659.5 KLO12062.1 - 0.0031 17.1 0.0 0.0051 16.4 0.0 1.4 1 0 0 1 1 1 1 KR domain ApbA PF02558.11 KLO12062.1 - 0.14 11.5 0.0 0.25 10.8 0.0 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA NAD_binding_10 PF13460.1 KLO12063.1 - 3.7e-07 30.3 0.0 1.3e-05 25.2 0.0 2.1 1 1 0 1 1 1 1 NADH(P)-binding adh_short PF00106.20 KLO12063.1 - 0.00071 19.5 0.0 0.0012 18.8 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase Epimerase PF01370.16 KLO12063.1 - 0.019 14.3 0.0 0.031 13.7 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family adh_short_C2 PF13561.1 KLO12063.1 - 0.071 12.8 0.0 0.097 12.4 0.0 1.2 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase Methyltransf_23 PF13489.1 KLO12064.1 - 3.9e-07 29.9 0.0 5.5e-07 29.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KLO12064.1 - 9.1e-07 28.5 0.0 1.4e-06 27.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain CheR PF01739.13 KLO12064.1 - 8.5e-06 25.1 0.0 1.4e-05 24.4 0.0 1.2 1 0 0 1 1 1 1 CheR methyltransferase, SAM binding domain Methyltransf_11 PF08241.7 KLO12064.1 - 2.3e-05 24.8 0.0 3.6e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KLO12064.1 - 2.7e-05 24.5 0.0 4.7e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KLO12064.1 - 7.5e-05 23.2 0.0 0.00013 22.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KLO12064.1 - 0.0016 18.7 0.0 0.0028 18.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain ABC2_membrane PF01061.19 KLO12065.1 - 2.6e-67 226.0 61.6 3.5e-35 121.1 14.7 3.1 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.22 KLO12065.1 - 8e-34 116.8 0.0 5.1e-16 59.2 0.0 2.4 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.7 KLO12065.1 - 7.5e-23 80.1 10.6 2.9e-19 68.6 0.1 2.9 3 0 0 3 3 2 2 CDR ABC transporter cobW PF02492.14 KLO12065.1 - 1.2e-07 31.3 0.0 0.013 14.9 0.0 2.3 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain ABC_trans_N PF14510.1 KLO12065.1 - 3.1e-07 30.3 0.1 9.2e-07 28.8 0.0 1.9 1 0 0 1 1 1 1 ABC-transporter extracellular N-terminal AAA_22 PF13401.1 KLO12065.1 - 7.3e-06 26.1 0.9 0.21 11.6 0.0 3.2 2 2 0 2 2 2 2 AAA domain AAA_33 PF13671.1 KLO12065.1 - 1.4e-05 25.0 0.0 0.029 14.2 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.1 KLO12065.1 - 2.4e-05 23.8 0.1 0.031 13.6 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_10 PF12846.2 KLO12065.1 - 4.6e-05 22.9 0.1 0.00081 18.9 0.0 2.4 2 0 0 2 2 2 1 AAA-like domain AAA_18 PF13238.1 KLO12065.1 - 0.00014 22.1 0.7 0.33 11.2 0.0 3.9 4 0 0 4 4 4 1 AAA domain AAA_17 PF13207.1 KLO12065.1 - 0.00024 21.8 0.2 0.19 12.5 0.0 3.1 3 0 0 3 3 3 1 AAA domain AAA_28 PF13521.1 KLO12065.1 - 0.00053 19.9 0.1 0.33 10.9 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.1 KLO12065.1 - 0.003 17.0 0.8 0.045 13.2 0.1 2.4 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_16 PF13191.1 KLO12065.1 - 0.0038 17.2 0.4 0.2 11.6 0.1 2.7 2 1 0 2 2 2 1 AAA ATPase domain DUF258 PF03193.11 KLO12065.1 - 0.012 14.7 0.0 0.049 12.8 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function, DUF258 AAA_21 PF13304.1 KLO12065.1 - 0.015 15.2 0.0 6.8 6.5 0.0 2.6 2 0 0 2 2 2 0 AAA domain SMC_N PF02463.14 KLO12065.1 - 0.034 13.3 0.2 1.4 8.0 0.1 3.3 2 1 0 2 2 2 0 RecF/RecN/SMC N terminal domain UPF0079 PF02367.12 KLO12065.1 - 0.035 13.7 1.1 5.4 6.6 0.1 2.3 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 FtsK_SpoIIIE PF01580.13 KLO12065.1 - 0.069 12.6 3.0 6.9 6.0 0.1 2.8 2 1 1 3 3 3 0 FtsK/SpoIIIE family AAA PF00004.24 KLO12065.1 - 0.092 12.9 0.1 20 5.3 0.0 2.7 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.1 KLO12065.1 - 0.097 12.4 2.4 6.3 6.6 0.0 2.9 3 0 0 3 3 2 0 Part of AAA domain AAA_30 PF13604.1 KLO12065.1 - 0.19 11.2 0.4 2.3 7.7 0.0 2.2 2 0 0 2 2 2 0 AAA domain ABC2_membrane_3 PF12698.2 KLO12065.1 - 0.83 8.6 47.7 0.21 10.5 12.9 3.1 2 1 0 2 2 2 0 ABC-2 family transporter protein NACHT PF05729.7 KLO12065.1 - 1.9 8.1 4.4 13 5.3 0.0 2.8 3 0 0 3 3 3 0 NACHT domain Pkinase PF00069.20 KLO12067.1 - 6.8e-70 235.1 0.0 1.1e-69 234.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KLO12067.1 - 9.1e-52 175.6 0.0 1.4e-51 175.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KLO12067.1 - 4e-05 22.7 0.0 0.004 16.1 0.0 2.3 2 0 0 2 2 2 2 Kinase-like DUF1241 PF06840.6 KLO12067.1 - 0.0011 18.2 0.3 0.0022 17.2 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF1241) DUF605 PF04652.11 KLO12067.1 - 6 6.1 22.4 1.8 7.8 0.1 2.2 2 0 0 2 2 2 0 Vta1 like Ribosomal_L1 PF00687.16 KLO12068.1 - 7.3e-20 71.2 0.0 1.2e-19 70.5 0.0 1.4 1 1 0 1 1 1 1 Ribosomal protein L1p/L10e family zf-C2H2_4 PF13894.1 KLO12069.1 - 0.0059 16.8 8.9 0.74 10.2 0.6 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.21 KLO12069.1 - 3.2 8.2 10.7 10 6.7 2.1 2.8 2 0 0 2 2 2 0 Zinc finger, C2H2 type F-box-like PF12937.2 KLO12070.1 - 0.16 11.6 0.0 0.16 11.6 0.0 3.2 3 1 0 3 3 3 0 F-box-like HTH_Tnp_ISL3 PF13542.1 KLO12073.1 - 0.11 11.6 0.0 0.22 10.7 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 FHA PF00498.21 KLO12075.1 - 3.9e-10 39.7 0.0 1e-09 38.3 0.0 1.7 1 0 0 1 1 1 1 FHA domain BicD PF09730.4 KLO12075.1 - 0.0079 14.6 3.9 0.013 13.9 2.7 1.2 1 0 0 1 1 1 1 Microtubule-associated protein Bicaudal-D PEP-utilisers_N PF05524.8 KLO12075.1 - 0.23 11.2 4.2 2.2 8.1 0.2 2.4 1 1 1 2 2 2 0 PEP-utilising enzyme, N-terminal SAC3_GANP PF03399.11 KLO12076.1 - 4.4e-19 68.8 0.1 7.9e-19 68.0 0.1 1.4 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family DHH PF01368.15 KLO12076.1 - 0.036 13.6 0.0 0.094 12.3 0.0 1.6 1 0 0 1 1 1 0 DHH family Ribonuc_P_40 PF08584.6 KLO12076.1 - 0.15 11.0 0.1 0.26 10.2 0.0 1.3 1 0 0 1 1 1 0 Ribonuclease P 40kDa (Rpp40) subunit 2OG-FeII_Oxy_3 PF13640.1 KLO12078.1 - 4.4e-07 30.3 0.0 1.5e-06 28.6 0.0 1.9 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.15 KLO12078.1 - 1.2e-05 25.4 0.0 2.2e-05 24.6 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_4 PF13661.1 KLO12078.1 - 0.11 12.2 0.0 0.38 10.4 0.0 1.9 1 1 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily DUF3718 PF12514.3 KLO12083.1 - 0.0022 18.0 0.0 0.0044 17.0 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3718) PRCC PF10253.4 KLO12084.1 - 0.0019 18.9 0.8 0.0029 18.3 0.5 1.3 1 0 0 1 1 1 1 Mitotic checkpoint regulator, MAD2B-interacting DUF4140 PF13600.1 KLO12084.1 - 0.14 12.6 3.8 17 5.8 2.0 2.7 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) DUF3901 PF13040.1 KLO12085.1 - 0.13 11.6 2.4 0.25 10.6 1.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3901) DUF2719 PF10891.3 KLO12086.1 - 0.093 12.4 2.0 0.22 11.2 1.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2719) FYVE_2 PF02318.11 KLO12086.1 - 1.4 8.7 15.7 1.9 8.3 2.6 2.2 2 0 0 2 2 2 0 FYVE-type zinc finger Cytochrom_c3_2 PF14537.1 KLO12086.1 - 4.2 7.7 12.4 3.4 8.0 2.6 2.4 2 0 0 2 2 2 0 Cytochrome c3 Cytochrom_CIII PF02085.11 KLO12086.1 - 4.6 7.4 12.4 0.073 13.1 1.8 2.3 2 0 0 2 2 2 0 Class III cytochrome C family PIN_4 PF13638.1 KLO12088.1 - 1.3e-08 35.0 0.0 2e-08 34.4 0.0 1.4 1 0 0 1 1 1 1 PIN domain ENTH PF01417.15 KLO12089.1 - 2.7e-51 172.6 0.3 4.8e-51 171.8 0.2 1.4 1 0 0 1 1 1 1 ENTH domain ANTH PF07651.11 KLO12089.1 - 0.001 17.8 0.0 0.001 17.8 0.0 2.1 2 0 0 2 2 2 1 ANTH domain Peptidase_C12 PF01088.16 KLO12090.1 - 1.3e-46 158.4 0.0 4.3e-45 153.5 0.0 2.3 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 AAT PF03417.11 KLO12093.1 - 3e-13 49.7 0.0 3.3e-12 46.3 0.0 2.0 1 1 0 1 1 1 1 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase RNase_PH PF01138.16 KLO12094.1 - 2.1e-19 70.1 0.0 3.2e-19 69.5 0.0 1.3 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 Peptidase_M24 PF00557.19 KLO12095.1 - 4.4e-56 189.7 0.0 5.8e-56 189.3 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.11 KLO12095.1 - 2.5e-17 62.5 0.0 4.6e-17 61.6 0.0 1.4 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain DUF1639 PF07797.9 KLO12096.1 - 0.00013 21.2 0.7 0.38 10.1 0.1 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF1639) DUF2347 PF09804.4 KLO12097.1 - 6.5e-47 160.1 0.0 2.6e-46 158.1 0.0 1.9 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2347) SPA PF08616.5 KLO12097.1 - 0.00022 20.9 0.0 0.00059 19.5 0.0 1.7 2 0 0 2 2 2 1 Stabilization of polarity axis DUF4484 PF14831.1 KLO12097.1 - 0.00053 20.1 0.2 0.0017 18.4 0.0 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4484) Avl9 PF09794.4 KLO12097.1 - 0.001 17.6 0.0 7.4 4.9 0.0 3.2 3 0 0 3 3 3 3 Transport protein Avl9 Cellulase PF00150.13 KLO12098.1 - 7e-29 100.8 5.1 1.1e-28 100.2 3.5 1.2 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Cellulase PF00150.13 KLO12099.1 - 1e-30 106.9 0.6 1.6e-30 106.2 0.4 1.2 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) ARD PF03079.9 KLO12100.1 - 7.7e-47 159.1 0.0 9e-47 158.9 0.0 1.0 1 0 0 1 1 1 1 ARD/ARD' family Cupin_2 PF07883.6 KLO12100.1 - 1.2e-09 37.5 0.1 2.3e-09 36.6 0.1 1.4 1 0 0 1 1 1 1 Cupin domain AraC_binding PF02311.14 KLO12100.1 - 2e-07 30.7 0.0 2.8e-07 30.2 0.0 1.2 1 0 0 1 1 1 1 AraC-like ligand binding domain Cupin_1 PF00190.17 KLO12100.1 - 8.4e-05 22.0 0.0 0.00014 21.3 0.0 1.3 1 0 0 1 1 1 1 Cupin Cupin_3 PF05899.7 KLO12100.1 - 0.0036 16.6 0.0 0.007 15.7 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF861) Cupin_8 PF13621.1 KLO12100.1 - 0.012 15.1 0.0 0.024 14.1 0.0 1.3 1 1 0 1 1 1 0 Cupin-like domain Cupin_6 PF12852.2 KLO12100.1 - 0.044 13.3 0.0 0.061 12.9 0.0 1.2 1 0 0 1 1 1 0 Cupin SKG6 PF08693.5 KLO12101.1 - 3.8e-08 32.4 1.7 8.4e-08 31.4 1.2 1.6 1 0 0 1 1 1 1 Transmembrane alpha-helix domain DUF4448 PF14610.1 KLO12101.1 - 0.00055 19.4 0.0 0.0011 18.5 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) Asp PF00026.18 KLO12104.1 - 2.9e-20 72.7 0.1 2.7e-17 63.0 0.1 2.7 1 1 0 1 1 1 1 Eukaryotic aspartyl protease Asp_protease_2 PF13650.1 KLO12104.1 - 5.1e-05 23.6 2.1 0.011 16.1 0.0 4.3 5 0 0 5 5 5 1 Aspartyl protease gag-asp_proteas PF13975.1 KLO12104.1 - 0.01 15.6 0.8 0.044 13.5 0.1 2.3 2 0 0 2 2 2 0 gag-polyprotein putative aspartyl protease UPF0220 PF05255.6 KLO12104.1 - 0.39 9.9 2.4 1.2 8.4 0.5 2.4 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0220) MAGE PF01454.14 KLO12107.1 - 1.1e-33 116.2 0.5 5.3e-29 100.9 0.0 2.2 1 1 0 2 2 2 2 MAGE family DUF1471 PF07338.8 KLO12107.1 - 0.054 13.1 0.6 2.2 7.9 0.1 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1471) SEP PF08059.8 KLO12108.1 - 1.2e-24 86.4 0.0 2.2e-24 85.5 0.0 1.5 1 0 0 1 1 1 1 SEP domain UBX PF00789.15 KLO12108.1 - 2.5e-13 49.8 0.2 4.4e-13 49.0 0.1 1.4 1 0 0 1 1 1 1 UBX domain PI-PLC-X PF00388.14 KLO12109.1 - 9.6e-42 141.8 0.0 1.5e-41 141.2 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.14 KLO12109.1 - 6.8e-27 93.7 0.0 1e-26 93.2 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain Ion_trans PF00520.26 KLO12110.1 - 8e-83 276.5 82.8 1.8e-27 95.9 8.1 6.9 6 1 1 7 7 7 6 Ion transport protein HMG14_17 PF01101.13 KLO12110.1 - 0.62 10.7 0.1 1.3 9.7 0.1 1.5 1 0 0 1 1 1 0 HMG14 and HMG17 PCI PF01399.22 KLO12111.1 - 1.9e-05 24.9 1.1 0.0051 17.0 0.0 3.1 3 0 0 3 3 3 2 PCI domain HA2 PF04408.18 KLO12112.1 - 9e-29 99.5 0.3 2e-28 98.3 0.2 1.6 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.11 KLO12112.1 - 2e-20 72.7 0.0 4.8e-20 71.4 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.26 KLO12112.1 - 3.5e-12 46.0 0.0 6.3e-12 45.1 0.0 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 KLO12112.1 - 0.002 17.6 0.0 0.0036 16.8 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase tRNA-synt_1 PF00133.17 KLO12113.1 - 1e-208 694.2 0.0 5e-208 691.9 0.0 1.9 1 1 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.8 KLO12113.1 - 5.1e-36 123.7 0.1 5.1e-36 123.7 0.1 1.8 2 0 0 2 2 2 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.6 KLO12113.1 - 4.4e-16 58.5 0.0 1.1e-07 30.8 0.0 4.4 4 1 0 4 4 4 3 tRNA synthetases class I (M) tRNA-synt_1_2 PF13603.1 KLO12113.1 - 8.8e-11 41.4 0.0 4.2e-07 29.4 0.0 2.6 1 1 1 2 2 2 2 Leucyl-tRNA synthetase, Domain 2 Val_tRNA-synt_C PF10458.4 KLO12113.1 - 8.6e-05 22.5 8.7 0.00033 20.6 1.2 3.0 3 0 0 3 3 3 1 Valyl tRNA synthetase tRNA binding arm tRNA-synt_1d PF00750.14 KLO12113.1 - 0.0025 16.7 0.0 0.02 13.7 0.0 2.2 2 0 0 2 2 2 1 tRNA synthetases class I (R) tRNA-synt_1e PF01406.14 KLO12113.1 - 0.016 14.3 0.0 0.11 11.5 0.0 2.1 2 0 0 2 2 2 0 tRNA synthetases class I (C) catalytic domain Peptidase_M48 PF01435.13 KLO12114.1 - 1.1e-28 100.3 0.0 2.3e-28 99.3 0.0 1.5 1 1 0 1 1 1 1 Peptidase family M48 Septin PF00735.13 KLO12115.1 - 4.8e-114 380.1 0.5 6.8e-114 379.6 0.3 1.2 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.18 KLO12115.1 - 2e-07 30.9 0.0 3.9e-07 30.0 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase DUF258 PF03193.11 KLO12115.1 - 3.4e-07 29.5 0.1 8.1e-07 28.3 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function, DUF258 GTP_EFTU PF00009.22 KLO12115.1 - 2.4e-06 27.1 0.1 5.1e-05 22.7 0.0 2.5 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain PduV-EutP PF10662.4 KLO12115.1 - 0.00024 20.5 1.2 0.038 13.4 0.0 2.7 2 1 1 3 3 3 1 Ethanolamine utilisation - propanediol utilisation Miro PF08477.8 KLO12115.1 - 0.00039 20.8 0.0 0.0011 19.4 0.0 1.9 1 0 0 1 1 1 1 Miro-like protein ABC_tran PF00005.22 KLO12115.1 - 0.0014 18.9 0.2 0.005 17.1 0.0 1.9 2 0 0 2 2 2 1 ABC transporter AIG1 PF04548.11 KLO12115.1 - 0.0017 17.4 0.0 0.0038 16.3 0.0 1.6 1 0 0 1 1 1 1 AIG1 family AAA_22 PF13401.1 KLO12115.1 - 0.0023 18.0 1.6 0.019 15.1 0.0 2.7 3 1 0 3 3 2 1 AAA domain AAA_16 PF13191.1 KLO12115.1 - 0.0062 16.5 1.0 0.037 14.0 0.0 2.5 3 0 0 3 3 3 1 AAA ATPase domain Ras PF00071.17 KLO12115.1 - 0.0068 15.8 0.0 0.018 14.4 0.0 1.7 1 0 0 1 1 1 1 Ras family Dynamin_N PF00350.18 KLO12115.1 - 0.0069 16.2 7.0 0.4 10.4 0.0 3.1 2 1 1 3 3 3 2 Dynamin family AAA_24 PF13479.1 KLO12115.1 - 0.0082 15.7 0.0 0.017 14.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain MobB PF03205.9 KLO12115.1 - 0.015 14.9 0.0 0.039 13.6 0.0 1.8 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_33 PF13671.1 KLO12115.1 - 0.016 15.0 0.1 0.081 12.7 0.0 2.2 2 1 0 2 2 2 0 AAA domain AAA_10 PF12846.2 KLO12115.1 - 0.019 14.3 0.0 0.042 13.2 0.0 1.4 1 1 0 1 1 1 0 AAA-like domain NB-ARC PF00931.17 KLO12115.1 - 0.027 13.3 0.0 0.058 12.2 0.0 1.5 1 0 0 1 1 1 0 NB-ARC domain Val_tRNA-synt_C PF10458.4 KLO12115.1 - 0.032 14.2 0.7 0.032 14.2 0.5 3.0 3 0 0 3 3 3 0 Valyl tRNA synthetase tRNA binding arm Arch_ATPase PF01637.13 KLO12115.1 - 0.034 13.8 2.1 0.045 13.4 0.0 2.0 2 0 0 2 2 2 0 Archaeal ATPase Sigma54_activat PF00158.21 KLO12115.1 - 0.034 13.6 0.1 0.064 12.7 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain NACHT PF05729.7 KLO12115.1 - 0.037 13.6 0.0 0.079 12.6 0.0 1.6 1 0 0 1 1 1 0 NACHT domain FeoB_N PF02421.13 KLO12115.1 - 0.074 12.3 0.1 0.22 10.8 0.1 1.8 1 1 0 1 1 1 0 Ferrous iron transport protein B FtsK_SpoIIIE PF01580.13 KLO12115.1 - 0.079 12.4 3.6 0.11 11.9 0.1 2.4 3 0 0 3 3 2 0 FtsK/SpoIIIE family AAA_14 PF13173.1 KLO12115.1 - 0.093 12.6 0.5 0.19 11.6 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.1 KLO12115.1 - 0.1 12.1 0.0 0.19 11.2 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain Bac_DnaA PF00308.13 KLO12115.1 - 0.11 12.1 3.6 2.1 7.9 0.4 2.7 2 1 0 2 2 2 0 Bacterial dnaA protein Bap31 PF05529.7 KLO12115.1 - 6.8 6.0 9.3 0.81 9.1 2.8 2.1 2 0 0 2 2 2 0 B-cell receptor-associated protein 31-like AAA_23 PF13476.1 KLO12115.1 - 9.3 6.5 15.8 2.1e+02 2.0 10.9 2.2 1 1 0 1 1 1 0 AAA domain GTP_EFTU PF00009.22 KLO12116.1 - 6.7e-57 191.9 0.0 1.1e-56 191.2 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.13 KLO12116.1 - 9.3e-36 122.0 0.1 5.1e-35 119.6 0.0 2.1 2 0 0 2 2 2 1 Elongation factor G, domain IV EFG_II PF14492.1 KLO12116.1 - 2.6e-30 104.0 0.0 5.9e-30 102.9 0.0 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_C PF00679.19 KLO12116.1 - 5.9e-23 80.5 0.0 1.6e-22 79.1 0.0 1.8 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 KLO12116.1 - 4e-12 46.0 0.0 1.7e-11 44.0 0.0 2.1 2 0 0 2 2 2 1 Elongation factor Tu domain 2 DUF3337 PF11816.3 KLO12117.1 - 2.2e-39 135.8 0.2 5.5e-39 134.4 0.0 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF3337) WD40 PF00400.27 KLO12117.1 - 2.2e-33 112.8 24.0 3.9e-11 42.3 0.1 7.0 6 1 0 6 6 6 6 WD domain, G-beta repeat DUF308 PF03729.8 KLO12118.1 - 0.05 13.5 1.9 0.1 12.5 1.3 1.4 1 0 0 1 1 1 0 Short repeat of unknown function (DUF308) CAP59_mtransfer PF11735.3 KLO12119.1 - 9.1e-48 162.5 0.0 1.5e-47 161.8 0.0 1.3 1 0 0 1 1 1 1 Cryptococcal mannosyltransferase 1 WD40 PF00400.27 KLO12120.1 - 1.1e-46 155.0 21.2 4.3e-11 42.2 0.2 6.3 6 0 0 6 6 6 6 WD domain, G-beta repeat TFIIIC_delta PF12657.2 KLO12120.1 - 6.6e-05 22.6 11.1 0.052 13.2 0.1 4.1 3 1 1 4 4 4 3 Transcription factor IIIC subunit delta N-term AMP-binding PF00501.23 KLO12121.1 - 2.4e-52 177.7 0.0 3.1e-52 177.3 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme Calcipressin PF04847.7 KLO12122.1 - 0.35 10.4 3.4 0.4 10.2 2.4 1.3 1 1 0 1 1 1 0 Calcipressin DUF1116 PF06545.6 KLO12125.1 - 0.053 12.5 0.0 0.059 12.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1116) SBP PF03110.9 KLO12125.1 - 0.44 10.8 5.6 0.84 9.9 3.9 1.5 1 0 0 1 1 1 0 SBP domain Spt5-NGN PF03439.8 KLO12127.1 - 2.3e-09 36.8 0.0 7e-09 35.3 0.0 1.9 1 0 0 1 1 1 1 Early transcription elongation factor of RNA pol II, NGN section KOW PF00467.24 KLO12127.1 - 1.4e-07 30.8 18.5 0.00074 19.1 0.0 6.0 6 0 0 6 6 6 2 KOW motif Pro-kuma_activ PF09286.6 KLO12132.1 - 2.8e-32 111.7 0.2 1.7e-31 109.2 0.0 2.2 3 0 0 3 3 3 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.17 KLO12132.1 - 3.9e-08 32.7 2.1 3.9e-08 32.7 1.5 1.9 1 1 0 2 2 2 1 Subtilase family DUF1962 PF09227.5 KLO12133.1 - 0.085 12.9 0.8 0.23 11.5 0.3 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF1962) KSHV_K8 PF07188.6 KLO12134.1 - 0.12 11.5 0.3 0.13 11.4 0.2 1.1 1 0 0 1 1 1 0 Kaposi's sarcoma-associated herpesvirus (KSHV) K8 protein PNPase PF03726.9 KLO12134.1 - 0.58 10.4 5.0 1 9.6 3.5 1.5 1 1 0 1 1 1 0 Polyribonucleotide nucleotidyltransferase, RNA binding domain TFIIB PF00382.14 KLO12140.1 - 0.15 11.8 0.2 0.23 11.2 0.1 1.3 1 0 0 1 1 1 0 Transcription factor TFIIB repeat F-box-like PF12937.2 KLO12143.1 - 0.03 14.0 0.0 0.081 12.6 0.0 1.7 1 0 0 1 1 1 0 F-box-like Med9 PF07544.8 KLO12150.1 - 0.032 13.9 2.0 0.1 12.3 1.4 1.8 1 0 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 KAR9 PF08580.5 KLO12154.1 - 0.14 10.4 1.5 0.19 9.9 1.0 1.1 1 0 0 1 1 1 0 Yeast cortical protein KAR9 Velvet PF11754.3 KLO12155.1 - 1.2e-29 103.3 0.0 9.9e-29 100.3 0.0 2.1 1 1 0 1 1 1 1 Velvet factor VWA_2 PF13519.1 KLO12156.1 - 0.0002 21.5 0.0 0.00094 19.3 0.0 1.9 1 1 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.23 KLO12156.1 - 0.00073 19.2 0.0 0.0015 18.2 0.0 1.5 1 1 0 1 1 1 1 von Willebrand factor type A domain DUF4646 PF15496.1 KLO12159.1 - 2.9e-15 56.4 0.3 1.4e-14 54.2 0.2 2.1 1 1 0 1 1 1 1 Domain of unknown function (DUF4646) TPR_11 PF13414.1 KLO12160.1 - 1.3e-17 63.1 11.6 2.3e-16 59.1 3.0 3.1 3 0 0 3 3 3 2 TPR repeat TPR_2 PF07719.12 KLO12160.1 - 9.5e-09 34.5 6.1 0.066 13.1 0.9 5.2 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_1 PF00515.23 KLO12160.1 - 5.4e-08 32.1 5.5 0.095 12.3 1.2 4.0 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_17 PF13431.1 KLO12160.1 - 7e-05 22.7 2.0 0.21 11.8 0.0 3.5 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.1 KLO12160.1 - 0.00016 21.9 6.5 0.28 11.5 0.0 4.2 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.1 KLO12160.1 - 0.0012 19.3 1.6 19 6.2 0.0 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_12 PF13424.1 KLO12160.1 - 0.011 15.6 1.2 14 5.6 0.0 3.6 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.1 KLO12160.1 - 0.029 15.0 13.5 0.24 12.1 0.3 4.1 3 1 1 4 4 4 0 Tetratricopeptide repeat Response_reg PF00072.19 KLO12161.1 - 2.6e-20 72.4 0.0 4.4e-20 71.7 0.0 1.4 1 0 0 1 1 1 1 Response regulator receiver domain 4HBT_2 PF13279.1 KLO12162.1 - 6.5e-06 26.6 0.0 1.5e-05 25.4 0.0 1.6 1 0 0 1 1 1 1 Thioesterase-like superfamily PTR2 PF00854.16 KLO12163.1 - 2.3e-49 168.1 11.6 4.4e-47 160.6 8.1 2.1 1 1 0 1 1 1 1 POT family MFS_1 PF07690.11 KLO12163.1 - 0.045 12.4 33.3 0.25 10.0 23.1 2.1 1 1 0 1 1 1 0 Major Facilitator Superfamily Peptidase_C25_C PF03785.9 KLO12164.1 - 0.72 9.7 4.1 2.1 8.2 0.7 2.5 2 0 0 2 2 2 0 Peptidase family C25, C terminal ig-like domain ABC_membrane PF00664.18 KLO12165.1 - 3.7e-48 164.3 28.7 2.6e-22 79.5 4.0 3.8 4 0 0 4 4 4 3 ABC transporter transmembrane region ABC_tran PF00005.22 KLO12165.1 - 2.9e-47 160.3 0.0 8.6e-29 100.5 0.1 2.7 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 KLO12165.1 - 9.1e-09 35.6 0.0 0.0034 17.3 0.0 4.3 2 2 0 3 3 3 2 AAA domain SMC_N PF02463.14 KLO12165.1 - 9.3e-07 28.2 0.4 0.0051 16.0 1.8 3.4 2 2 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_25 PF13481.1 KLO12165.1 - 1.2e-06 28.1 0.1 0.0023 17.3 0.0 2.8 2 0 0 2 2 2 2 AAA domain T2SE PF00437.15 KLO12165.1 - 1.5e-05 24.0 0.3 0.064 12.1 0.0 2.3 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_29 PF13555.1 KLO12165.1 - 0.00027 20.4 0.4 0.14 11.7 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.1 KLO12165.1 - 0.00071 19.7 0.9 4.4 7.4 0.0 3.6 3 0 0 3 3 3 1 AAA domain AAA_10 PF12846.2 KLO12165.1 - 0.0056 16.1 0.0 3 7.1 0.0 2.4 2 0 0 2 2 2 2 AAA-like domain AAA_16 PF13191.1 KLO12165.1 - 0.021 14.8 3.8 6 6.8 0.8 3.1 2 1 0 2 2 2 0 AAA ATPase domain AAA_19 PF13245.1 KLO12165.1 - 0.027 14.2 1.6 2 8.2 0.0 3.6 3 0 0 3 3 3 0 Part of AAA domain DUF87 PF01935.12 KLO12165.1 - 0.041 13.6 0.1 0.15 11.8 0.1 2.0 1 0 0 1 1 1 0 Domain of unknown function DUF87 RseC_MucC PF04246.7 KLO12165.1 - 0.043 13.3 0.0 0.19 11.3 0.0 2.1 1 0 0 1 1 1 0 Positive regulator of sigma(E), RseC/MucC AAA_23 PF13476.1 KLO12165.1 - 0.053 13.8 1.2 4.5 7.5 0.0 3.0 3 0 0 3 3 2 0 AAA domain MobB PF03205.9 KLO12165.1 - 0.11 12.2 0.3 4.8 6.8 0.0 2.6 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B ADH_zinc_N PF00107.21 KLO12166.1 - 8.3e-26 90.0 0.6 1.4e-25 89.3 0.4 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KLO12166.1 - 8.6e-26 89.8 7.9 1.7e-25 88.9 5.5 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 KLO12166.1 - 0.00076 20.3 0.2 0.0016 19.3 0.1 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase SH2_2 PF14633.1 KLO12166.1 - 0.16 11.0 0.0 0.25 10.3 0.0 1.2 1 0 0 1 1 1 0 SH2 domain Gti1_Pac2 PF09729.4 KLO12170.1 - 1.2e-28 100.0 3.1 1.2e-26 93.5 2.2 2.2 1 1 0 1 1 1 1 Gti1/Pac2 family DUF605 PF04652.11 KLO12171.1 - 0.27 10.5 19.3 0.4 10.0 13.4 1.2 1 0 0 1 1 1 0 Vta1 like F-box PF00646.28 KLO12172.1 - 7.3e-06 25.4 1.6 1.4e-05 24.5 0.0 2.4 3 0 0 3 3 3 1 F-box domain F-box-like PF12937.2 KLO12172.1 - 0.00097 18.8 1.8 0.0029 17.2 0.0 2.4 2 0 0 2 2 2 1 F-box-like COPI_C PF06957.6 KLO12172.1 - 0.074 11.5 0.0 0.12 10.8 0.0 1.2 1 0 0 1 1 1 0 Coatomer (COPI) alpha subunit C-terminus Git3 PF11710.3 KLO12173.1 - 1.3e-06 28.1 8.7 4e-06 26.5 6.0 1.7 1 1 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 Git3_C PF11970.3 KLO12173.1 - 0.00034 20.3 0.9 0.00098 18.8 0.6 1.7 1 0 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 C-term HATPase_c PF02518.21 KLO12174.1 - 2e-21 75.7 0.0 3.8e-21 74.8 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 KLO12174.1 - 8.5e-16 57.9 0.2 1.5e-14 53.9 0.1 2.4 1 1 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.20 KLO12174.1 - 9.5e-06 25.5 0.1 4.9e-05 23.2 0.0 2.3 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain ISN1 PF06437.6 KLO12174.1 - 0.031 13.0 0.1 0.049 12.3 0.1 1.2 1 0 0 1 1 1 0 IMP-specific 5'-nucleotidase Herpes_gE PF02480.11 KLO12175.1 - 0.014 13.6 0.0 0.016 13.4 0.0 1.1 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E KRE9 PF05390.6 KLO12175.1 - 0.078 13.3 0.6 0.078 13.3 0.4 1.6 2 0 0 2 2 2 0 Yeast cell wall synthesis protein KRE9/KNH1 Rifin_STEVOR PF02009.11 KLO12175.1 - 0.12 12.0 0.0 0.15 11.6 0.0 1.1 1 0 0 1 1 1 0 Rifin/stevor family Pkinase_Tyr PF07714.12 KLO12176.1 - 2.2e-52 177.7 0.0 3.3e-52 177.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 KLO12176.1 - 1.6e-43 148.7 0.0 3.1e-43 147.8 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.9 KLO12176.1 - 0.00028 20.0 0.0 0.00056 19.0 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 KLO12176.1 - 0.00029 20.2 0.0 0.00067 19.0 0.0 1.5 1 0 0 1 1 1 1 RIO1 family TPR_12 PF13424.1 KLO12176.1 - 0.11 12.4 0.2 1.1 9.3 0.0 2.6 3 0 0 3 3 3 0 Tetratricopeptide repeat Peptidase_S9 PF00326.16 KLO12177.1 - 2.7e-40 137.8 0.0 4e-40 137.3 0.0 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family DLH PF01738.13 KLO12177.1 - 1.5e-12 47.2 0.1 7.9e-12 44.9 0.1 1.9 1 1 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_2 PF02230.11 KLO12177.1 - 2.8e-08 33.4 0.0 0.0064 15.9 0.0 2.4 2 0 0 2 2 2 2 Phospholipase/Carboxylesterase Abhydrolase_6 PF12697.2 KLO12177.1 - 6.2e-07 29.5 0.5 2e-06 27.8 0.1 2.0 2 1 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KLO12177.1 - 7.8e-07 28.9 0.0 1.3e-06 28.2 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.8 KLO12177.1 - 2.7e-05 23.8 0.1 0.00019 21.0 0.1 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold PD40 PF07676.7 KLO12177.1 - 6e-05 22.6 0.8 0.024 14.2 0.1 2.8 2 0 0 2 2 2 2 WD40-like Beta Propeller Repeat LIP PF03583.9 KLO12177.1 - 0.012 14.7 0.0 3.9 6.5 0.1 2.2 1 1 0 2 2 2 0 Secretory lipase Esterase_phd PF10503.4 KLO12177.1 - 0.015 14.5 0.2 0.041 13.1 0.2 1.7 1 1 0 1 1 1 0 Esterase PHB depolymerase Abhydrolase_4 PF08386.5 KLO12177.1 - 0.083 12.7 0.0 0.2 11.5 0.0 1.6 1 0 0 1 1 1 0 TAP-like protein DUF2517 PF10725.4 KLO12179.1 - 0.57 9.9 2.7 0.95 9.1 1.9 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2517) Cpn60_TCP1 PF00118.19 KLO12184.1 - 1.3e-118 396.7 4.7 1.5e-118 396.5 3.3 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Rubella_E2 PF05749.6 KLO12184.1 - 0.086 12.0 0.0 0.14 11.3 0.0 1.2 1 0 0 1 1 1 0 Rubella membrane glycoprotein E2 CBM_5_12 PF02839.9 KLO12185.1 - 1.8e-13 49.7 12.6 1.4e-11 43.7 7.5 2.8 2 0 0 2 2 2 2 Carbohydrate binding domain SecY PF00344.15 KLO12186.1 - 2.6e-94 315.9 9.5 2.6e-94 315.9 6.6 1.5 2 0 0 2 2 2 1 SecY translocase Plug_translocon PF10559.4 KLO12186.1 - 1.6e-19 69.1 0.2 6e-19 67.2 0.1 2.1 1 0 0 1 1 1 1 Plug domain of Sec61p DUF3817 PF12823.2 KLO12186.1 - 0.056 13.8 0.9 16 6.0 0.1 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3817) Ribonuclease_3 PF00636.21 KLO12187.1 - 1.8e-42 144.3 0.0 3e-20 72.7 0.0 2.7 2 0 0 2 2 2 2 Ribonuclease III domain Ribonucleas_3_3 PF14622.1 KLO12187.1 - 2.3e-23 82.5 2.7 5.7e-09 36.0 0.1 4.9 3 2 1 4 4 4 3 Ribonuclease-III-like DEAD PF00270.24 KLO12187.1 - 8.1e-18 64.4 0.0 1.6e-17 63.4 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KLO12187.1 - 1.4e-12 47.3 0.2 4e-12 45.8 0.1 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Dicer_dimer PF03368.9 KLO12187.1 - 6.8e-12 45.0 0.0 1.7e-11 43.7 0.0 1.7 1 0 0 1 1 1 1 Dicer dimerisation domain ResIII PF04851.10 KLO12187.1 - 4.3e-11 42.9 0.0 8.5e-11 42.0 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit JmjC PF02373.17 KLO12188.1 - 5.8e-38 129.6 0.1 1.2e-37 128.6 0.1 1.5 1 0 0 1 1 1 1 JmjC domain, hydroxylase JmjN PF02375.12 KLO12188.1 - 2.1e-15 55.9 0.1 3.6e-15 55.1 0.1 1.4 1 0 0 1 1 1 1 jmjN domain zf-HC5HC2H PF13771.1 KLO12188.1 - 1.5e-14 53.9 1.3 3.3e-14 52.8 0.3 2.0 2 0 0 2 2 2 1 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.1 KLO12188.1 - 2.6e-10 40.2 4.3 2.6e-10 40.2 3.0 2.2 2 1 0 2 2 2 1 PHD-zinc-finger like domain PHD PF00628.24 KLO12188.1 - 0.001 18.6 4.7 0.0025 17.4 3.2 1.6 1 0 0 1 1 1 1 PHD-finger FANCL_C PF11793.3 KLO12188.1 - 0.1 12.5 2.5 0.23 11.4 1.7 1.5 1 0 0 1 1 1 0 FANCL C-terminal domain Ribosomal_60s PF00428.14 KLO12190.1 - 1e-28 99.5 13.6 1.3e-28 99.2 9.5 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein ThiF PF00899.16 KLO12191.1 - 2.2e-31 108.5 0.0 4.1e-31 107.6 0.0 1.4 1 0 0 1 1 1 1 ThiF family Shikimate_DH PF01488.15 KLO12191.1 - 0.013 15.6 0.0 0.034 14.2 0.0 1.7 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Mit_KHE1 PF10173.4 KLO12193.1 - 6.7e-48 163.0 0.0 1.1e-47 162.3 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial K+-H+ exchange-related Amidohydro_5 PF13594.1 KLO12194.1 - 0.00014 21.6 0.0 0.00028 20.6 0.0 1.5 1 0 0 1 1 1 1 Amidohydrolase Roughex PF06020.6 KLO12195.1 - 0.18 10.4 0.1 0.33 9.5 0.0 1.4 1 0 0 1 1 1 0 Drosophila roughex protein GMC_oxred_N PF00732.14 KLO12196.1 - 3.8e-65 219.9 0.0 5e-65 219.5 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 KLO12196.1 - 3.6e-35 121.3 0.0 6.7e-35 120.4 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 KLO12196.1 - 1.2e-05 24.4 0.3 0.0012 17.8 0.1 2.5 2 1 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KLO12196.1 - 3.9e-05 23.5 0.6 0.00028 20.8 0.1 2.6 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 KLO12196.1 - 0.00027 19.9 0.1 0.0004 19.4 0.1 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_3 PF13738.1 KLO12196.1 - 0.00055 20.0 0.1 0.13 12.2 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 KLO12196.1 - 0.00065 18.6 0.6 0.039 12.8 0.2 2.2 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.9 KLO12196.1 - 0.0022 17.8 0.1 0.13 12.0 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 KLO12196.1 - 0.011 14.7 0.0 0.023 13.7 0.0 1.4 1 0 0 1 1 1 0 Thi4 family CoA_binding_3 PF13727.1 KLO12196.1 - 0.026 14.3 0.1 0.13 12.1 0.0 1.9 2 0 0 2 2 2 0 CoA-binding domain HI0933_like PF03486.9 KLO12196.1 - 0.13 10.7 0.1 0.33 9.3 0.0 1.6 2 0 0 2 2 2 0 HI0933-like protein DLH PF01738.13 KLO12197.1 - 1.5e-21 76.7 0.0 2.9e-21 75.7 0.0 1.5 1 1 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 KLO12197.1 - 1.1e-07 31.7 0.0 2.6e-07 30.4 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KLO12197.1 - 0.037 13.8 0.0 0.063 13.1 0.0 1.5 1 1 0 1 1 1 0 Alpha/beta hydrolase family Dabb PF07876.7 KLO12198.1 - 1.7e-16 60.4 0.0 1.9e-16 60.2 0.0 1.0 1 0 0 1 1 1 1 Stress responsive A/B Barrel Domain F-actin_cap_A PF01267.12 KLO12199.1 - 1.6e-93 312.6 0.0 2e-93 312.3 0.0 1.0 1 0 0 1 1 1 1 F-actin capping protein alpha subunit MarC PF01914.12 KLO12202.1 - 0.00026 20.1 0.3 0.00026 20.1 0.2 1.7 2 0 0 2 2 2 1 MarC family integral membrane protein DAD PF02109.11 KLO12204.1 - 0.68 10.0 8.5 2 8.5 0.6 2.7 1 1 1 2 2 2 0 DAD family TAN PF11640.3 KLO12207.1 - 0.12 12.1 0.7 0.21 11.3 0.5 1.3 1 0 0 1 1 1 0 Telomere-length maintenance and DNA damage repair PROCN PF08083.6 KLO12212.1 - 1.4e-199 662.7 4.5 1.8e-198 659.0 3.0 2.7 2 1 0 2 2 2 1 PROCN (NUC071) domain PRP8_domainIV PF12134.3 KLO12212.1 - 1.3e-125 417.3 0.8 2.1e-125 416.5 0.5 1.4 1 0 0 1 1 1 1 PRP8 domain IV core U6-snRNA_bdg PF10596.4 KLO12212.1 - 2.2e-92 306.6 1.2 5.6e-92 305.3 0.8 1.7 1 0 0 1 1 1 1 U6-snRNA interacting domain of PrP8 PRO8NT PF08082.6 KLO12212.1 - 1e-79 265.4 2.0 1e-79 265.4 1.4 2.4 2 0 0 2 2 2 1 PRO8NT (NUC069), PrP8 N-terminal domain U5_2-snRNA_bdg PF10597.4 KLO12212.1 - 1e-69 232.4 0.1 2e-69 231.4 0.1 1.5 1 0 0 1 1 1 1 U5-snRNA binding site 2 of PrP8 RRM_4 PF10598.4 KLO12212.1 - 8.7e-44 147.3 0.2 2e-43 146.1 0.2 1.6 1 0 0 1 1 1 1 RNA recognition motif of the spliceosomal PrP8 PROCT PF08084.6 KLO12212.1 - 1.6e-37 128.0 0.0 3.6e-37 126.8 0.0 1.7 1 0 0 1 1 1 1 PROCT (NUC072) domain JAB PF01398.16 KLO12212.1 - 0.00014 21.5 0.0 0.00036 20.2 0.0 1.7 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease DUF837 PF05769.6 KLO12213.1 - 0.00024 20.6 10.5 0.0047 16.4 2.6 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF837) Nsp1_C PF05064.8 KLO12213.1 - 0.0054 16.3 2.0 0.0054 16.3 1.4 2.3 1 1 1 2 2 2 1 Nsp1-like C-terminal region DUF972 PF06156.8 KLO12213.1 - 0.037 14.3 9.1 0.21 11.9 2.5 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF972) OmpH PF03938.9 KLO12213.1 - 1.4 8.7 6.9 3.2 7.6 4.8 1.5 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) NYD-SP28_assoc PF14775.1 KLO12213.1 - 2.9 7.6 10.4 2.1 8.0 0.9 3.0 3 0 0 3 3 3 0 Sperm tail C-terminal domain Rho_N PF07498.7 KLO12214.1 - 7.4e-06 25.6 0.3 1.5e-05 24.6 0.2 1.5 1 0 0 1 1 1 1 Rho termination factor, N-terminal domain SAP PF02037.22 KLO12214.1 - 0.0038 16.6 0.2 0.011 15.2 0.1 1.8 1 0 0 1 1 1 1 SAP domain F-box PF00646.28 KLO12214.1 - 0.045 13.4 0.0 0.26 10.9 0.0 2.2 2 0 0 2 2 2 0 F-box domain FAD_binding_3 PF01494.14 KLO12216.1 - 2.6e-19 69.5 0.0 6.7e-09 35.2 0.0 2.4 2 1 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.1 KLO12216.1 - 0.004 17.1 0.1 0.0095 15.9 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 KLO12216.1 - 0.026 14.3 0.2 1.9 8.2 0.1 2.3 2 0 0 2 2 2 0 FAD-NAD(P)-binding Trp_halogenase PF04820.9 KLO12216.1 - 0.03 12.9 0.3 0.46 9.0 0.1 2.1 1 1 1 2 2 2 0 Tryptophan halogenase DAO PF01266.19 KLO12216.1 - 0.05 12.4 0.1 0.17 10.7 0.1 1.8 2 0 0 2 2 2 0 FAD dependent oxidoreductase Hom_end PF05204.9 KLO12216.1 - 0.12 12.2 0.0 0.24 11.3 0.0 1.3 1 0 0 1 1 1 0 Homing endonuclease U6-snRNA_bdg PF10596.4 KLO12218.1 - 0.00026 20.4 0.3 0.00036 19.9 0.2 1.2 1 0 0 1 1 1 1 U6-snRNA interacting domain of PrP8 U6-snRNA_bdg PF10596.4 KLO12219.1 - 5.8e-21 74.5 0.0 9.2e-21 73.8 0.0 1.3 1 1 0 1 1 1 1 U6-snRNA interacting domain of PrP8 PROCT PF08084.6 KLO12220.1 - 6.9e-10 38.7 0.0 1e-09 38.1 0.0 1.2 1 0 0 1 1 1 1 PROCT (NUC072) domain PRP8_domainIV PF12134.3 KLO12220.1 - 0.001 18.5 0.0 0.0013 18.0 0.0 1.1 1 0 0 1 1 1 1 PRP8 domain IV core Zn_clus PF00172.13 KLO12222.1 - 6.4e-10 38.7 17.3 1.2e-09 37.8 12.0 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain adh_short_C2 PF13561.1 KLO12223.1 - 2.5e-22 79.8 0.7 7.5e-21 74.9 0.5 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 KLO12223.1 - 8.9e-21 74.5 1.3 6.2e-14 52.2 0.0 2.3 2 0 0 2 2 2 2 short chain dehydrogenase KR PF08659.5 KLO12223.1 - 2.6e-08 33.7 0.2 7.5e-08 32.2 0.0 1.7 2 0 0 2 2 2 1 KR domain 3HCDH_N PF02737.13 KLO12223.1 - 0.01 15.4 0.3 0.03 13.9 0.2 1.7 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Epimerase PF01370.16 KLO12223.1 - 0.075 12.4 0.1 2.8 7.3 0.0 2.2 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family Shikimate_DH PF01488.15 KLO12223.1 - 0.1 12.6 0.3 0.22 11.6 0.2 1.6 1 1 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase NAD_binding_10 PF13460.1 KLO12223.1 - 0.12 12.3 0.2 0.82 9.6 0.1 2.1 2 0 0 2 2 2 0 NADH(P)-binding Glyco_tran_WecB PF03808.8 KLO12223.1 - 0.12 11.7 0.0 0.22 10.9 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferase WecB/TagA/CpsF family FAD_binding_2 PF00890.19 KLO12224.1 - 3.3e-46 157.9 0.4 1.1e-45 156.2 0.3 1.7 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 KLO12224.1 - 3.6e-08 32.6 3.5 2.8e-07 29.7 2.4 2.1 1 1 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.9 KLO12224.1 - 2.7e-07 29.4 1.4 0.013 14.0 0.0 3.0 3 0 0 3 3 3 2 HI0933-like protein Pyr_redox_2 PF07992.9 KLO12224.1 - 9.8e-07 28.8 0.2 9.5e-05 22.3 0.2 2.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 KLO12224.1 - 3.8e-06 26.2 2.7 5.5e-05 22.4 1.8 2.1 1 1 0 1 1 1 1 FAD dependent oxidoreductase GIDA PF01134.17 KLO12224.1 - 0.00011 21.2 7.3 0.0015 17.4 0.3 3.0 3 0 0 3 3 3 2 Glucose inhibited division protein A NAD_binding_8 PF13450.1 KLO12224.1 - 0.00016 21.6 0.1 0.0011 18.9 0.1 2.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 KLO12224.1 - 0.00049 20.2 0.1 0.046 13.7 0.1 2.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GMC_oxred_N PF00732.14 KLO12224.1 - 0.012 14.8 0.0 0.72 8.9 0.0 2.2 2 0 0 2 2 2 0 GMC oxidoreductase DUF4449 PF14613.1 KLO12225.1 - 1.4e-29 103.1 1.0 4.1e-29 101.6 0.7 1.9 1 0 0 1 1 1 1 Protein of unknown function (DUF4449) DUF1470 PF07336.6 KLO12225.1 - 0.16 12.2 8.0 0.028 14.7 1.9 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1470) NMO PF03060.10 KLO12226.1 - 5.3e-66 223.0 0.8 6.6e-66 222.7 0.5 1.1 1 0 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.20 KLO12226.1 - 6.3e-09 35.1 0.0 0.0033 16.3 0.0 2.2 1 1 1 2 2 2 2 IMP dehydrogenase / GMP reductase domain TMP-TENI PF02581.12 KLO12226.1 - 0.012 14.7 0.1 0.024 13.7 0.1 1.5 1 0 0 1 1 1 0 Thiamine monophosphate synthase/TENI His_biosynth PF00977.16 KLO12226.1 - 0.043 13.0 0.1 0.096 11.9 0.1 1.6 1 0 0 1 1 1 0 Histidine biosynthesis protein FMN_dh PF01070.13 KLO12226.1 - 0.052 12.3 0.5 0.089 11.6 0.4 1.4 1 0 0 1 1 1 0 FMN-dependent dehydrogenase AhpC-TSA PF00578.16 KLO12227.1 - 8.7e-32 109.4 0.0 1.2e-31 108.9 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 KLO12227.1 - 5.4e-21 74.6 0.0 9.1e-21 73.9 0.0 1.3 1 0 0 1 1 1 1 Redoxin AhpC-TSA_2 PF13911.1 KLO12227.1 - 0.003 17.4 0.0 0.0048 16.8 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA antioxidant enzyme Mitofilin PF09731.4 KLO12227.1 - 0.36 9.4 3.0 0.44 9.1 2.1 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein TFIIA PF03153.8 KLO12227.1 - 0.7 9.7 2.9 0.78 9.5 2.0 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SUR7 PF06687.7 KLO12228.1 - 6.9e-10 38.8 6.3 1.8e-09 37.5 4.3 1.6 1 1 0 1 1 1 1 SUR7/PalI family DUF2207 PF09972.4 KLO12228.1 - 0.026 13.1 1.8 0.028 13.0 0.1 1.7 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) Herpes_gE PF02480.11 KLO12228.1 - 0.028 12.6 0.0 0.047 11.9 0.0 1.2 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E DAHP_synth_1 PF00793.15 KLO12229.1 - 6.6e-94 313.5 0.0 8.5e-94 313.2 0.0 1.1 1 0 0 1 1 1 1 DAHP synthetase I family zf-Tim10_DDP PF02953.10 KLO12230.1 - 7.1e-18 63.6 4.2 1e-17 63.1 2.9 1.2 1 0 0 1 1 1 1 Tim10/DDP family zinc finger DUF805 PF05656.9 KLO12231.1 - 0.036 13.8 0.0 0.048 13.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF805) Lactamase_B PF00753.22 KLO12234.1 - 7.2e-11 42.0 0.1 1.1e-10 41.4 0.0 1.4 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 KLO12234.1 - 5.7e-05 22.7 0.0 7.7e-05 22.3 0.0 1.4 1 1 0 1 1 1 1 Beta-lactamase superfamily domain F-box-like PF12937.2 KLO12235.1 - 5.6e-05 22.7 0.0 0.00022 20.8 0.0 2.1 1 1 0 1 1 1 1 F-box-like F-box-like PF12937.2 KLO12236.1 - 3.8e-06 26.5 0.2 1.3e-05 24.8 0.1 2.0 1 0 0 1 1 1 1 F-box-like Acetyltransf_1 PF00583.19 KLO12237.1 - 0.00045 20.1 0.4 0.0053 16.7 0.0 2.5 2 1 0 2 2 2 1 Acetyltransferase (GNAT) family DUF4199 PF13858.1 KLO12239.1 - 4.4 7.2 7.9 2.7 7.8 1.9 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF4199) PLDc PF00614.17 KLO12240.1 - 1.5e-12 46.8 0.6 2.6e-05 23.8 0.0 2.5 2 0 0 2 2 2 2 Phospholipase D Active site motif PX PF00787.19 KLO12240.1 - 9e-12 44.7 0.3 3.4e-09 36.5 0.0 3.6 3 0 0 3 3 3 1 PX domain PLDc_2 PF13091.1 KLO12240.1 - 2.6e-11 43.3 0.0 6.2e-07 29.2 0.0 2.6 2 0 0 2 2 2 2 PLD-like domain PH PF00169.24 KLO12240.1 - 0.0031 17.6 0.1 0.012 15.8 0.0 2.0 1 1 0 1 1 1 1 PH domain PH_7 PF15408.1 KLO12240.1 - 0.0091 15.8 0.1 0.019 14.8 0.1 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain Abhydrolase_5 PF12695.2 KLO12241.1 - 1.6e-05 24.6 0.0 3.1e-05 23.7 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.8 KLO12241.1 - 7.6e-05 22.3 0.1 0.00013 21.6 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Lactamase_B PF00753.22 KLO12242.1 - 1.5e-07 31.2 6.0 2.6e-07 30.4 4.1 1.5 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 KLO12242.1 - 0.0011 18.5 0.2 0.0017 17.9 0.1 1.6 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Pkinase PF00069.20 KLO12243.1 - 5.5e-55 186.3 0.0 7e-55 185.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KLO12243.1 - 9.5e-26 90.4 0.8 3.4e-24 85.3 0.5 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KLO12243.1 - 3.4e-07 29.5 0.0 1.2e-06 27.7 0.0 1.8 2 0 0 2 2 2 1 Kinase-like RIO1 PF01163.17 KLO12243.1 - 0.00069 19.0 2.1 0.0055 16.0 0.2 2.6 3 0 0 3 3 3 1 RIO1 family Kdo PF06293.9 KLO12243.1 - 0.0007 18.7 0.5 0.0011 18.1 0.3 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KLO12243.1 - 0.0092 15.7 0.0 1.1 8.9 0.0 2.2 1 1 1 2 2 2 1 Phosphotransferase enzyme family Sigma70_r1_2 PF00140.15 KLO12243.1 - 0.12 12.0 1.6 44 3.8 0.0 3.3 3 0 0 3 3 3 0 Sigma-70 factor, region 1.2 IATP PF04568.7 KLO12244.1 - 0.01 15.8 0.9 0.016 15.2 0.7 1.3 1 0 0 1 1 1 0 Mitochondrial ATPase inhibitor, IATP DUF605 PF04652.11 KLO12244.1 - 1.6 8.0 8.6 1.8 7.8 6.0 1.2 1 0 0 1 1 1 0 Vta1 like vATP-synt_AC39 PF01992.11 KLO12245.1 - 2.2e-103 345.9 0.0 2.5e-103 345.7 0.0 1.0 1 0 0 1 1 1 1 ATP synthase (C/AC39) subunit Nop14 PF04147.7 KLO12246.1 - 6.7 4.4 12.1 0.084 10.7 3.3 1.6 2 0 0 2 2 2 0 Nop14-like family Adaptin_N PF01602.15 KLO12249.1 - 5.8e-19 67.8 0.1 1.7e-18 66.2 0.1 1.6 1 1 0 1 1 1 1 Adaptin N terminal region Cohesin_HEAT PF12765.2 KLO12249.1 - 0.00082 19.2 0.3 0.0064 16.4 0.0 2.7 1 1 1 2 2 2 1 HEAT repeat associated with sister chromatid cohesion HEAT_2 PF13646.1 KLO12249.1 - 0.0054 16.9 0.8 0.081 13.2 0.3 3.0 2 0 0 2 2 2 1 HEAT repeats HEAT PF02985.17 KLO12249.1 - 0.0073 16.3 0.2 0.72 10.0 0.0 3.8 4 0 0 4 4 4 1 HEAT repeat Cnd1 PF12717.2 KLO12249.1 - 0.0092 15.8 0.0 0.15 11.9 0.0 2.3 2 0 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 Proteasom_PSMB PF10508.4 KLO12249.1 - 0.1 10.8 0.5 0.39 8.9 0.1 2.1 2 1 0 2 2 2 0 Proteasome non-ATPase 26S subunit Carboxyl_trans PF01039.17 KLO12250.1 - 1.3e-140 469.0 0.1 1.7e-140 468.6 0.0 1.0 1 0 0 1 1 1 1 Carboxyl transferase domain MdcE PF06833.6 KLO12250.1 - 0.0032 16.7 0.0 1.6 7.9 0.0 2.2 2 0 0 2 2 2 2 Malonate decarboxylase gamma subunit (MdcE) Herpes_gE PF02480.11 KLO12251.1 - 0.037 12.3 0.0 0.071 11.3 0.0 1.4 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E IncA PF04156.9 KLO12251.1 - 0.068 12.7 0.0 0.068 12.7 0.0 2.1 2 0 0 2 2 2 0 IncA protein CcmD PF04995.9 KLO12251.1 - 0.17 11.6 0.4 0.47 10.2 0.3 1.7 1 0 0 1 1 1 0 Heme exporter protein D (CcmD) TraT PF05818.7 KLO12251.1 - 4.7 6.5 4.7 49 3.2 0.0 2.6 2 0 0 2 2 2 0 Enterobacterial TraT complement resistance protein Reo_sigmaC PF04582.7 KLO12253.1 - 0.0034 16.6 34.1 0.026 13.6 1.2 4.6 1 1 4 5 5 5 3 Reovirus sigma C capsid protein DUF4382 PF14321.1 KLO12253.1 - 0.0034 17.4 1.2 0.0099 15.9 0.1 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF4382) Spc7 PF08317.6 KLO12253.1 - 0.0055 15.4 11.7 0.0055 15.4 8.1 5.5 1 1 4 6 6 6 4 Spc7 kinetochore protein HALZ PF02183.13 KLO12253.1 - 0.0065 16.1 4.3 0.0065 16.1 3.0 6.0 6 0 0 6 6 6 2 Homeobox associated leucine zipper CorA PF01544.13 KLO12253.1 - 3.3 6.6 32.5 0.16 10.9 3.4 4.4 2 2 2 5 5 5 0 CorA-like Mg2+ transporter protein PPR_2 PF13041.1 KLO12254.1 - 6.8e-42 141.2 0.0 9.2e-10 38.3 0.0 8.8 6 2 3 9 9 9 8 PPR repeat family PPR_3 PF13812.1 KLO12254.1 - 2.8e-25 86.4 7.0 0.0044 17.1 0.0 10.3 12 0 0 12 12 12 6 Pentatricopeptide repeat domain PPR PF01535.15 KLO12254.1 - 2.6e-14 52.0 4.5 0.0019 18.0 0.0 9.5 10 1 0 10 10 10 2 PPR repeat PPR_1 PF12854.2 KLO12254.1 - 6.3e-12 44.7 4.8 0.0087 15.5 0.0 7.3 9 0 0 9 9 9 4 PPR repeat ECSIT PF06239.6 KLO12254.1 - 4.1e-06 25.8 0.0 0.056 12.3 0.0 5.0 4 3 2 6 6 6 2 Evolutionarily conserved signalling intermediate in Toll pathway DUF1018 PF06252.7 KLO12254.1 - 0.00051 20.5 0.1 0.6 10.6 0.0 3.0 3 0 0 3 3 3 2 Protein of unknown function (DUF1018) Rad21_Rec8_N PF04825.8 KLO12255.1 - 9.5e-41 138.2 0.0 1.7e-40 137.3 0.0 1.5 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein Rad21_Rec8 PF04824.11 KLO12255.1 - 1.1e-10 40.5 0.0 2e-10 39.7 0.0 1.5 1 0 0 1 1 1 1 Conserved region of Rad21 / Rec8 like protein ScpA_ScpB PF02616.9 KLO12255.1 - 0.016 14.7 0.0 0.47 9.9 0.0 2.2 2 0 0 2 2 2 0 ScpA/B protein Glyco_hydro_16 PF00722.16 KLO12256.1 - 2.2e-06 27.1 0.1 4.8e-06 25.9 0.0 1.7 2 0 0 2 2 2 1 Glycosyl hydrolases family 16 Asp PF00026.18 KLO12257.1 - 1.6e-70 237.9 1.4 1.9e-70 237.6 1.0 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 KLO12257.1 - 3.2e-05 23.9 0.3 0.00011 22.2 0.1 1.9 2 0 0 2 2 2 1 Xylanase inhibitor N-terminal RhoGAP PF00620.22 KLO12258.1 - 2.9e-43 147.0 0.0 5.2e-43 146.2 0.0 1.4 1 0 0 1 1 1 1 RhoGAP domain LIM PF00412.17 KLO12258.1 - 1.7e-17 63.2 20.7 1.1e-10 41.4 0.8 3.0 3 0 0 3 3 3 2 LIM domain C1_1 PF00130.17 KLO12258.1 - 0.00024 20.7 6.1 0.00024 20.7 4.2 3.7 3 1 1 4 4 4 2 Phorbol esters/diacylglycerol binding domain (C1 domain) DUF972 PF06156.8 KLO12258.1 - 0.15 12.3 8.3 0.037 14.3 0.8 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF972) RICH PF05062.7 KLO12258.1 - 1.1 9.4 3.3 1.4 9.1 0.3 2.3 1 1 1 2 2 2 0 RICH domain PTPLA PF04387.9 KLO12259.1 - 1.2e-44 151.6 6.4 2.3e-44 150.7 4.4 1.5 1 1 0 1 1 1 1 Protein tyrosine phosphatase-like protein, PTPLA BTB PF00651.26 KLO12260.1 - 3.6e-12 46.2 0.0 4.3e-05 23.4 0.0 2.3 2 0 0 2 2 2 2 BTB/POZ domain bZIP_1 PF00170.16 KLO12261.1 - 3.5e-05 23.6 8.1 3.5e-05 23.6 5.6 2.5 2 1 1 3 3 3 1 bZIP transcription factor FlgN PF05130.7 KLO12261.1 - 7.8 6.7 14.8 1.8 8.8 5.6 2.4 2 0 0 2 2 2 0 FlgN protein Metallophos PF00149.23 KLO12262.1 - 7.4e-28 97.3 0.3 9.8e-21 74.0 0.2 2.2 2 0 0 2 2 2 2 Calcineurin-like phosphoesterase PPP5 PF08321.7 KLO12262.1 - 2.5e-13 49.8 0.0 8.5e-07 28.9 0.0 2.3 2 0 0 2 2 2 2 PPP5 TPR repeat region TPR_1 PF00515.23 KLO12262.1 - 2.3e-10 39.6 0.3 1.8e-06 27.2 0.0 3.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.1 KLO12262.1 - 3.5e-10 39.3 0.3 7.4e-10 38.3 0.1 1.7 2 0 0 2 2 2 1 TPR repeat TPR_2 PF07719.12 KLO12262.1 - 5e-07 29.1 0.3 3.7e-05 23.2 0.0 2.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_17 PF13431.1 KLO12262.1 - 0.0014 18.6 0.7 2.4 8.5 0.0 2.9 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.1 KLO12262.1 - 0.0052 17.4 0.2 0.014 16.0 0.1 1.8 1 1 0 1 1 1 1 Tetratricopeptide repeat TPR_9 PF13371.1 KLO12262.1 - 0.0099 15.7 0.6 0.0099 15.7 0.4 1.9 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.1 KLO12262.1 - 0.054 13.8 1.4 5.1 7.5 0.2 2.6 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.1 KLO12262.1 - 0.055 14.1 2.0 0.067 13.8 0.2 2.0 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_15 PF13429.1 KLO12262.1 - 0.071 12.1 0.1 0.15 11.1 0.1 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat Metallophos PF00149.23 KLO12263.1 - 3.8e-27 95.0 0.1 9.6e-22 77.3 0.1 2.2 2 0 0 2 2 2 2 Calcineurin-like phosphoesterase PPP5 PF08321.7 KLO12263.1 - 7.2e-06 25.9 0.0 0.096 12.7 0.0 2.3 2 0 0 2 2 2 2 PPP5 TPR repeat region Bunya_G1 PF03557.10 KLO12263.1 - 0.19 9.4 0.0 0.27 8.9 0.0 1.1 1 0 0 1 1 1 0 Bunyavirus glycoprotein G1 Alpha-L-AF_C PF06964.7 KLO12264.1 - 3.2e-39 134.5 0.8 6e-39 133.6 0.5 1.5 1 0 0 1 1 1 1 Alpha-L-arabinofuranosidase C-terminus CBM_4_9 PF02018.12 KLO12264.1 - 0.0078 16.2 0.6 0.023 14.6 0.4 1.8 1 0 0 1 1 1 1 Carbohydrate binding domain PLA2_B PF01735.13 KLO12267.1 - 1.6e-100 336.6 0.2 2.1e-100 336.2 0.1 1.1 1 0 0 1 1 1 1 Lysophospholipase catalytic domain UBA PF00627.26 KLO12268.1 - 3e-20 71.4 0.8 1.7e-12 46.7 0.2 2.6 2 0 0 2 2 2 2 UBA/TS-N domain ubiquitin PF00240.18 KLO12268.1 - 5.4e-20 70.5 0.6 8e-20 70.0 0.4 1.3 1 0 0 1 1 1 1 Ubiquitin family XPC-binding PF09280.6 KLO12268.1 - 1.6e-13 49.8 5.8 1.6e-13 49.8 4.0 2.0 2 0 0 2 2 2 1 XPC-binding domain Rad60-SLD PF11976.3 KLO12268.1 - 1.2e-10 40.9 1.1 2.1e-10 40.1 0.8 1.5 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 KLO12268.1 - 0.0064 16.6 0.0 0.011 15.9 0.0 1.4 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain Rad60-SLD_2 PF13881.1 KLO12268.1 - 0.012 15.4 0.0 0.027 14.3 0.0 1.5 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 KLO12268.1 - 0.04 14.1 0.2 0.066 13.4 0.2 1.3 1 0 0 1 1 1 0 Ubiquitin-like domain UBA_3 PF09288.5 KLO12268.1 - 0.051 13.1 0.0 0.33 10.5 0.0 2.1 2 0 0 2 2 2 0 Fungal ubiquitin-associated domain DUF3113 PF11310.3 KLO12268.1 - 0.14 11.8 1.8 26 4.6 0.1 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3113) TFIIA PF03153.8 KLO12268.1 - 0.38 10.6 11.1 0.7 9.7 7.5 1.5 1 1 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit MSA-2c PF12238.3 KLO12268.1 - 0.59 9.7 8.3 0.11 12.2 1.2 2.1 2 0 0 2 2 2 0 Merozoite surface antigen 2c LRR_4 PF12799.2 KLO12269.1 - 1.4e-10 40.4 10.3 0.0017 17.9 2.9 4.8 3 1 4 7 7 7 5 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KLO12269.1 - 4.3e-10 39.2 12.8 1.4e-06 27.9 4.6 4.0 3 1 0 3 3 3 2 Leucine rich repeat LRR_1 PF00560.28 KLO12269.1 - 0.0001 21.8 16.4 1.9 8.8 0.2 6.5 6 0 0 6 6 6 3 Leucine Rich Repeat LRR_6 PF13516.1 KLO12269.1 - 0.07 13.2 11.5 5.3 7.4 0.4 5.2 3 1 1 4 4 4 0 Leucine Rich repeat Arf PF00025.16 KLO12270.1 - 8.2e-78 259.6 0.0 9.3e-78 259.4 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.17 KLO12270.1 - 1.9e-13 50.1 0.0 2.1e-13 50.0 0.0 1.1 1 0 0 1 1 1 1 Ras family SRPRB PF09439.5 KLO12270.1 - 8.2e-12 44.7 0.0 1.1e-11 44.3 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.15 KLO12270.1 - 1.5e-11 43.6 1.5 2.8e-07 29.5 0.1 2.3 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.7 KLO12270.1 - 4.9e-09 35.6 0.0 6e-09 35.3 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 KLO12270.1 - 8.3e-07 29.5 0.0 1.1e-06 29.0 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 KLO12270.1 - 0.00035 20.5 0.1 0.00097 19.0 0.0 1.6 1 1 1 2 2 2 1 50S ribosome-binding GTPase 6PF2K PF01591.13 KLO12270.1 - 0.0043 16.1 0.1 0.0074 15.3 0.1 1.3 1 0 0 1 1 1 1 6-phosphofructo-2-kinase GTP_EFTU PF00009.22 KLO12270.1 - 0.019 14.3 0.0 0.066 12.6 0.0 1.7 1 1 1 2 2 2 0 Elongation factor Tu GTP binding domain ACT PF01842.20 KLO12270.1 - 0.062 12.7 0.0 0.14 11.7 0.0 1.6 1 0 0 1 1 1 0 ACT domain L27 PF02828.11 KLO12270.1 - 0.23 11.1 0.3 0.23 11.1 0.2 1.6 2 0 0 2 2 2 0 L27 domain PALP PF00291.20 KLO12271.1 - 5.9e-62 209.6 0.3 6.8e-62 209.4 0.2 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme DUF3602 PF12223.3 KLO12272.1 - 0.00014 22.1 19.1 0.0013 19.0 1.0 4.1 3 2 1 4 4 4 2 Protein of unknown function (DUF3602) SDA1 PF05285.7 KLO12272.1 - 0.73 9.0 11.7 0.15 11.3 4.1 2.2 2 0 0 2 2 2 0 SDA1 F-box-like PF12937.2 KLO12273.1 - 9.3e-08 31.6 0.0 2.1e-07 30.5 0.0 1.7 1 0 0 1 1 1 1 F-box-like RsbRD_N PF14361.1 KLO12273.1 - 0.029 14.8 0.0 14 6.1 0.0 2.5 2 0 0 2 2 2 0 RsbT co-antagonist protein rsbRD N-terminal domain F-box-like PF12937.2 KLO12274.1 - 6.9e-08 32.1 0.0 1.3e-07 31.1 0.0 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KLO12274.1 - 0.016 14.8 0.0 0.063 12.9 0.0 2.0 1 0 0 1 1 1 0 F-box domain LRR_4 PF12799.2 KLO12274.1 - 0.029 13.9 0.1 1.6 8.4 0.0 3.3 3 0 0 3 3 3 0 Leucine Rich repeats (2 copies) F-box-like PF12937.2 KLO12275.1 - 3.8e-10 39.3 0.6 6.8e-09 35.3 0.0 2.6 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 KLO12275.1 - 0.12 12.0 6.9 3.6 7.3 0.4 3.2 2 1 0 2 2 2 0 F-box domain LRR_4 PF12799.2 KLO12275.1 - 0.17 11.5 0.0 3.2 7.4 0.0 2.9 4 0 0 4 4 4 0 Leucine Rich repeats (2 copies) F-box-like PF12937.2 KLO12276.1 - 2.3e-09 36.8 0.1 5.6e-09 35.5 0.1 1.7 1 0 0 1 1 1 1 F-box-like Glyoxal_oxid_N PF07250.6 KLO12277.1 - 8.1e-45 152.7 0.3 7.4e-44 149.6 0.1 2.5 3 0 0 3 3 3 1 Glyoxal oxidase N-terminus DUF1929 PF09118.6 KLO12277.1 - 1.7e-24 85.7 0.1 3.4e-24 84.7 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1929) Kelch_4 PF13418.1 KLO12277.1 - 0.0053 16.5 5.8 0.084 12.6 0.0 3.7 3 0 0 3 3 3 2 Galactose oxidase, central domain Kelch_6 PF13964.1 KLO12277.1 - 0.054 13.6 4.8 7.6 6.8 0.7 3.9 3 1 0 3 3 3 0 Kelch motif Kelch_2 PF07646.10 KLO12277.1 - 3.8 7.4 6.6 3.7 7.4 0.0 3.6 4 0 0 4 4 4 0 Kelch motif Glyoxal_oxid_N PF07250.6 KLO12283.1 - 5.1e-44 150.1 0.2 5.7e-43 146.7 0.1 2.5 3 0 0 3 3 3 1 Glyoxal oxidase N-terminus DUF1929 PF09118.6 KLO12283.1 - 6.6e-23 80.6 0.2 1.3e-22 79.7 0.2 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1929) Kelch_4 PF13418.1 KLO12283.1 - 0.001 18.7 0.2 0.21 11.3 0.0 3.5 2 0 0 2 2 2 1 Galactose oxidase, central domain Pkinase PF00069.20 KLO12284.1 - 3.9e-18 65.5 0.0 1e-17 64.1 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KLO12284.1 - 1.7e-12 46.9 0.0 1.1e-09 37.7 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase APH PF01636.18 KLO12284.1 - 0.00016 21.4 0.1 0.003 17.3 0.0 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.17 KLO12284.1 - 0.014 14.7 0.0 0.026 13.8 0.0 1.4 1 0 0 1 1 1 0 RIO1 family Kdo PF06293.9 KLO12284.1 - 0.12 11.4 0.0 0.16 10.9 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Cupredoxin_1 PF13473.1 KLO12285.1 - 0.062 13.1 0.1 0.12 12.3 0.0 1.4 1 0 0 1 1 1 0 Cupredoxin-like domain Copper-bind PF00127.15 KLO12285.1 - 0.077 13.2 0.0 0.2 11.8 0.0 1.6 1 1 0 1 1 1 0 Copper binding proteins, plastocyanin/azurin family DUF3735 PF12537.3 KLO12285.1 - 0.75 9.8 3.6 17 5.5 0.0 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF3735) Herpes_gE PF02480.11 KLO12286.1 - 0.00094 17.5 0.0 0.0018 16.6 0.0 1.4 1 0 0 1 1 1 1 Alphaherpesvirus glycoprotein E EphA2_TM PF14575.1 KLO12286.1 - 0.031 14.6 0.0 0.21 11.9 0.0 2.2 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Shisa PF13908.1 KLO12286.1 - 0.43 10.7 0.0 0.43 10.7 0.0 2.9 2 1 1 3 3 3 0 Wnt and FGF inhibitory regulator HAS-barrel PF09378.5 KLO12287.1 - 0.083 12.7 0.0 0.16 11.8 0.0 1.4 1 0 0 1 1 1 0 HAS barrel domain Sporozoite_P67 PF05642.6 KLO12287.1 - 0.27 9.0 6.4 0.28 9.0 4.5 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Mucin PF01456.12 KLO12287.1 - 0.7 9.6 12.9 1.1 9.0 8.9 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein Myf5 PF12232.3 KLO12287.1 - 1.5 9.4 11.5 6.5 7.4 0.6 2.4 2 0 0 2 2 2 0 Myogenic determination factor 5 SKG6 PF08693.5 KLO12289.1 - 8.4e-05 21.8 0.1 0.00021 20.5 0.1 1.7 1 0 0 1 1 1 1 Transmembrane alpha-helix domain MGC-24 PF05283.6 KLO12289.1 - 0.00059 19.6 11.0 0.001 18.9 7.6 1.4 1 0 0 1 1 1 1 Multi-glycosylated core protein 24 (MGC-24) Mucin PF01456.12 KLO12289.1 - 0.11 12.2 17.5 0.23 11.2 12.1 1.6 1 0 0 1 1 1 0 Mucin-like glycoprotein Syndecan PF01034.15 KLO12289.1 - 0.14 11.8 0.0 0.36 10.5 0.0 1.7 1 0 0 1 1 1 0 Syndecan domain YajC PF02699.10 KLO12289.1 - 0.2 11.3 0.0 0.41 10.3 0.0 1.5 1 0 0 1 1 1 0 Preprotein translocase subunit Surp PF01805.15 KLO12290.1 - 8e-12 44.6 0.1 1.8e-11 43.4 0.0 1.7 1 0 0 1 1 1 1 Surp module RRM_1 PF00076.17 KLO12290.1 - 5.9e-08 32.2 0.0 0.017 14.7 0.0 2.8 1 1 1 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KLO12290.1 - 1.4e-05 24.9 0.0 9.5e-05 22.3 0.0 2.2 1 1 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KLO12290.1 - 0.011 15.5 0.0 0.033 14.0 0.0 1.8 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) KH_1 PF00013.24 KLO12291.1 - 1.2e-77 255.4 30.9 1.5e-12 46.9 1.2 12.6 14 0 0 14 14 14 10 KH domain KH_3 PF13014.1 KLO12291.1 - 1.9e-58 193.2 20.7 9.7e-09 34.6 0.1 11.8 11 0 0 11 11 11 10 KH domain KH_2 PF07650.12 KLO12291.1 - 2.8e-10 39.6 23.6 0.0052 16.3 0.2 7.5 6 2 0 7 7 7 5 KH domain KH_4 PF13083.1 KLO12291.1 - 2.2e-06 27.2 7.6 0.83 9.3 0.0 6.7 7 0 0 7 7 7 3 KH domain SLS PF14611.1 KLO12291.1 - 3.2e-05 23.4 23.4 0.018 14.5 0.0 7.1 6 3 2 8 8 8 2 Mitochondrial inner-membrane-bound regulator FCD PF07729.7 KLO12291.1 - 0.0065 16.7 0.7 0.1 12.8 0.0 3.2 3 0 0 3 3 3 1 FCD domain TRAM_LAG1_CLN8 PF03798.11 KLO12293.1 - 3.5e-05 23.4 6.7 3.5e-05 23.4 4.6 1.6 1 1 0 1 1 1 1 TLC domain GST_N_3 PF13417.1 KLO12296.1 - 9.3e-14 51.4 0.0 2.2e-13 50.2 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 KLO12296.1 - 9.2e-10 38.3 0.0 1.6e-09 37.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 KLO12296.1 - 2.5e-07 30.4 0.0 4.9e-07 29.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 KLO12296.1 - 9.5e-06 25.7 0.0 0.00015 21.8 0.0 2.9 2 1 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 KLO12296.1 - 0.0021 17.9 0.0 0.005 16.7 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 KLO12296.1 - 0.029 14.8 0.2 0.05 14.0 0.0 1.6 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain Redoxin PF08534.5 KLO12298.1 - 3.7e-36 123.8 0.0 4.3e-36 123.6 0.0 1.0 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.16 KLO12298.1 - 1.2e-13 50.7 0.0 1.4e-13 50.6 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family FAD_syn PF06574.7 KLO12298.1 - 0.1 12.2 0.0 0.15 11.6 0.0 1.3 1 0 0 1 1 1 0 FAD synthetase HMG_box PF00505.14 KLO12299.1 - 2.8e-19 69.1 9.1 6e-10 39.2 0.2 2.9 3 0 0 3 3 3 2 HMG (high mobility group) box HMG_box_2 PF09011.5 KLO12299.1 - 9.7e-15 54.6 2.6 2.9e-06 27.5 0.2 3.0 2 0 0 2 2 2 2 HMG-box domain Herpes_UL74 PF07982.7 KLO12299.1 - 0.51 8.9 4.0 0.84 8.2 2.8 1.3 1 0 0 1 1 1 0 Herpes UL74 glycoproteins GST_N_3 PF13417.1 KLO12300.1 - 5.1e-09 36.2 0.1 1.2e-08 35.0 0.1 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 KLO12300.1 - 2.3e-07 30.7 0.2 3.9e-07 29.9 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 KLO12300.1 - 0.013 15.4 0.0 0.033 14.0 0.0 1.7 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain ORC5_C PF14630.1 KLO12301.1 - 2.3e-42 145.3 0.0 3e-42 144.9 0.0 1.1 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 5 C-terminus PhzC-PhzF PF02567.11 KLO12302.1 - 8e-59 199.1 0.1 1.1e-58 198.7 0.1 1.2 1 0 0 1 1 1 1 Phenazine biosynthesis-like protein GST_N_3 PF13417.1 KLO12303.1 - 5.2e-19 68.2 0.0 2.4e-16 59.7 0.0 2.4 2 0 0 2 2 2 2 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 KLO12303.1 - 7e-12 45.1 0.0 2e-11 43.7 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 KLO12303.1 - 9.1e-07 28.6 0.3 1.9e-06 27.6 0.2 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 KLO12303.1 - 0.00059 19.7 0.0 0.001 18.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 KLO12303.1 - 0.032 14.3 0.0 0.11 12.7 0.0 1.8 1 1 0 1 1 1 0 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 KLO12304.1 - 2.9e-12 46.6 0.0 7e-12 45.4 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 KLO12304.1 - 2.4e-09 37.0 0.0 4.1e-09 36.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 KLO12304.1 - 0.016 15.3 0.0 0.072 13.2 0.0 2.1 1 1 0 1 1 1 0 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 KLO12304.1 - 0.018 14.8 0.1 0.044 13.6 0.0 1.7 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 KLO12304.1 - 0.024 14.5 0.0 0.042 13.8 0.0 1.3 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 KLO12305.1 - 4.4e-13 49.2 0.0 1.2e-12 47.9 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 KLO12305.1 - 8.2e-09 35.3 0.0 1.5e-08 34.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 KLO12305.1 - 0.00078 19.3 0.0 0.0013 18.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 KLO12305.1 - 0.01 16.3 0.0 0.017 15.6 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 KLO12305.1 - 0.043 13.7 0.1 0.19 11.6 0.0 2.0 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 KLO12305.1 - 0.1 12.7 0.0 0.78 9.9 0.0 2.5 2 2 0 2 2 2 0 Glutathione S-transferase, N-terminal domain Med8 PF10232.4 KLO12306.1 - 4.5e-05 23.0 5.1 0.00019 21.0 3.5 1.9 1 1 0 1 1 1 1 Mediator of RNA polymerase II transcription complex subunit 8 GST_N_3 PF13417.1 KLO12307.1 - 1.2e-05 25.3 0.0 7.9e-05 22.8 0.0 2.1 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 KLO12307.1 - 3.5e-05 23.6 0.0 8.4e-05 22.4 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 KLO12307.1 - 0.0042 17.5 0.0 0.0062 17.0 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 KLO12307.1 - 0.022 14.6 0.0 0.044 13.6 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain ADH_zinc_N PF00107.21 KLO12308.1 - 1.6e-24 85.9 0.0 2.4e-24 85.3 0.0 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase TrkA_N PF02254.13 KLO12308.1 - 0.012 15.6 0.0 0.031 14.2 0.0 1.7 2 0 0 2 2 2 0 TrkA-N domain AlaDh_PNT_C PF01262.16 KLO12308.1 - 0.053 13.0 0.0 0.088 12.3 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Peptidase_S80 PF07230.6 KLO12308.1 - 0.078 11.2 0.0 0.1 10.9 0.0 1.1 1 0 0 1 1 1 0 Bacteriophage T4-like capsid assembly protein (Gp20) ADH_zinc_N PF00107.21 KLO12309.1 - 3.4e-22 78.3 0.0 5.6e-22 77.6 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase DUF2855 PF11017.3 KLO12309.1 - 0.0096 15.0 0.0 0.016 14.3 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2855) TrkA_N PF02254.13 KLO12309.1 - 0.016 15.1 0.0 0.04 13.9 0.0 1.7 1 0 0 1 1 1 0 TrkA-N domain DUF824 PF05688.6 KLO12309.1 - 0.61 9.7 3.2 1.6 8.4 0.2 2.7 3 0 0 3 3 3 0 Salmonella repeat of unknown function (DUF824) E1-E2_ATPase PF00122.15 KLO12310.1 - 1.4e-15 56.9 0.0 1.4e-15 56.9 0.0 2.4 3 0 0 3 3 3 1 E1-E2 ATPase HAD PF12710.2 KLO12310.1 - 3.1e-12 47.0 0.0 2.3e-11 44.2 0.0 2.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 KLO12310.1 - 5.5e-12 45.4 0.0 1.3e-11 44.3 0.0 1.6 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase PF00702.21 KLO12310.1 - 5.6e-12 46.5 1.2 3.8e-08 33.9 0.6 3.2 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 KLO12310.1 - 0.0023 17.5 0.5 0.019 14.5 0.0 2.5 3 0 0 3 3 3 1 haloacid dehalogenase-like hydrolase Hydrophobin PF01185.13 KLO12311.1 - 2.7e-06 27.7 7.6 2.1e-05 24.9 5.6 1.8 1 1 1 2 2 2 2 Fungal hydrophobin Hydrophobin PF01185.13 KLO12312.1 - 1.3e-09 38.3 12.2 2.3e-09 37.5 8.4 1.4 1 0 0 1 1 1 1 Fungal hydrophobin Hydrophobin PF01185.13 KLO12313.1 - 1.1e-10 41.8 6.3 1.5e-10 41.3 4.4 1.2 1 0 0 1 1 1 1 Fungal hydrophobin RNase_P_p30 PF01876.11 KLO12317.1 - 1.2e-33 115.4 0.0 2.5e-33 114.4 0.0 1.5 1 0 0 1 1 1 1 RNase P subunit p30 DBD_Tnp_Mut PF03108.10 KLO12318.1 - 0.0089 15.5 1.2 0.0089 15.5 0.8 1.6 2 0 0 2 2 2 1 MuDR family transposase Cytomega_TRL10 PF06084.6 KLO12318.1 - 0.064 13.0 0.2 0.11 12.3 0.2 1.3 1 0 0 1 1 1 0 Cytomegalovirus TRL10 protein zf-C2H2 PF00096.21 KLO12318.1 - 0.099 13.0 12.1 0.1 13.0 2.1 2.5 2 0 0 2 2 2 0 Zinc finger, C2H2 type PRiA4_ORF3 PF07929.6 KLO12320.1 - 1.5e-27 96.2 0.1 3.1e-27 95.1 0.1 1.5 1 0 0 1 1 1 1 Plasmid pRiA4b ORF-3-like protein zf-MYND PF01753.13 KLO12320.1 - 9.9e-12 44.5 12.0 1.8e-11 43.7 8.3 1.4 1 0 0 1 1 1 1 MYND finger Utp14 PF04615.8 KLO12323.1 - 1.6 6.8 30.0 2 6.5 20.8 1.0 1 0 0 1 1 1 0 Utp14 protein GrpE PF01025.14 KLO12323.1 - 3.2 7.2 13.8 0.22 11.0 5.8 1.7 2 0 0 2 2 2 0 GrpE Peptidase_C14 PF00656.17 KLO12325.1 - 3.6e-62 210.2 0.0 5.2e-62 209.7 0.0 1.2 1 0 0 1 1 1 1 Caspase domain TFIIA PF03153.8 KLO12325.1 - 0.23 11.3 1.9 0.26 11.1 1.3 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SelP_N PF04592.9 KLO12325.1 - 4.2 6.6 20.2 7.9 5.7 14.0 1.3 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Zip PF02535.17 KLO12325.1 - 5.4 5.9 13.4 8.4 5.2 9.3 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Peptidase_C14 PF00656.17 KLO12326.1 - 7.4e-45 153.5 0.0 2.5e-43 148.5 0.0 2.2 1 1 0 1 1 1 1 Caspase domain Macoilin PF09726.4 KLO12326.1 - 8.6 4.5 6.8 11 4.1 4.7 1.1 1 0 0 1 1 1 0 Transmembrane protein Synaptobrevin PF00957.16 KLO12328.1 - 5.1e-14 51.6 0.2 7.9e-14 51.0 0.2 1.3 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.1 KLO12328.1 - 2.1e-07 30.3 0.0 3.7e-07 29.5 0.0 1.4 1 0 0 1 1 1 1 Regulated-SNARE-like domain MBOAT_2 PF13813.1 KLO12329.1 - 3.4e-12 46.2 2.9 3.4e-12 46.2 2.0 2.4 2 0 0 2 2 2 1 Membrane bound O-acyl transferase family YCII PF03795.9 KLO12330.1 - 9.1e-07 28.9 0.0 1.1e-06 28.6 0.0 1.1 1 0 0 1 1 1 1 YCII-related domain VWA_2 PF13519.1 KLO12331.1 - 6.8e-07 29.5 0.0 1.3e-06 28.6 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain BolA PF01722.13 KLO12331.1 - 0.099 12.6 0.0 0.22 11.5 0.0 1.5 1 0 0 1 1 1 0 BolA-like protein Sec23_trunk PF04811.10 KLO12331.1 - 0.13 11.5 0.0 0.24 10.6 0.0 1.3 1 0 0 1 1 1 0 Sec23/Sec24 trunk domain DcpS_C PF11969.3 KLO12332.1 - 4.3e-23 81.7 0.0 7.5e-23 80.9 0.0 1.4 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding DcpS PF05652.7 KLO12332.1 - 3e-20 72.6 0.0 6.9e-20 71.4 0.0 1.6 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme (DcpS) N-terminal HIT PF01230.18 KLO12332.1 - 0.033 14.7 0.2 0.17 12.4 0.0 2.2 1 1 1 2 2 2 0 HIT domain Fer2_3 PF13085.1 KLO12334.1 - 3.6e-33 113.6 0.1 5.6e-33 113.0 0.1 1.3 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer4_17 PF13534.1 KLO12334.1 - 8e-11 42.1 7.6 8e-11 42.1 5.3 2.3 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_8 PF13183.1 KLO12334.1 - 2.7e-08 33.7 6.1 2.7e-08 33.7 4.2 2.0 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_9 PF13187.1 KLO12334.1 - 0.00012 22.2 4.7 0.014 15.6 0.3 3.1 3 0 0 3 3 3 2 4Fe-4S dicluster domain Fer4_18 PF13746.1 KLO12334.1 - 0.00024 21.4 2.5 0.00024 21.4 1.7 2.7 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_10 PF13237.1 KLO12334.1 - 0.00042 20.0 6.1 0.00042 20.0 4.2 2.2 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_7 PF12838.2 KLO12334.1 - 0.00064 20.0 4.1 0.00064 20.0 2.8 2.3 2 1 0 2 2 2 1 4Fe-4S dicluster domain Fer2 PF00111.22 KLO12334.1 - 0.0058 16.3 1.4 0.0058 16.3 1.0 2.2 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Fer4_15 PF13459.1 KLO12334.1 - 0.56 10.8 6.4 1.3 9.6 0.2 3.0 4 0 0 4 4 4 0 4Fe-4S single cluster domain DNA_pol3_tau_4 PF12168.3 KLO12334.1 - 1.3 9.4 3.7 1.8 9.0 0.9 2.1 2 0 0 2 2 2 0 DNA polymerase III subunits tau domain IV DnaB-binding AhpC-TSA PF00578.16 KLO12335.1 - 2e-28 98.5 0.0 3.3e-28 97.8 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 KLO12335.1 - 5.6e-21 74.6 0.0 8.5e-21 74.0 0.0 1.3 1 0 0 1 1 1 1 Redoxin AhpC-TSA_2 PF13911.1 KLO12335.1 - 0.0026 17.6 0.0 0.0054 16.6 0.0 1.5 1 0 0 1 1 1 1 AhpC/TSA antioxidant enzyme DUF3629 PF12302.3 KLO12335.1 - 0.11 11.8 1.5 0.17 11.2 1.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3629) adh_short PF00106.20 KLO12336.1 - 7.6e-27 94.2 0.7 1e-26 93.8 0.5 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KLO12336.1 - 1.4e-22 80.6 0.0 2.8e-22 79.6 0.0 1.4 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KLO12336.1 - 1.8e-11 44.0 0.4 2.9e-11 43.3 0.3 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 KLO12336.1 - 0.033 13.6 0.0 0.042 13.2 0.0 1.3 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family adh_short PF00106.20 KLO12337.1 - 1.3e-30 106.4 4.2 1.9e-30 105.9 2.9 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KLO12337.1 - 4.2e-22 79.0 3.3 5e-22 78.8 2.3 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KLO12337.1 - 1.6e-14 53.9 3.4 3e-14 53.0 2.4 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 KLO12337.1 - 0.0058 16.0 0.7 0.0076 15.7 0.5 1.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 KLO12337.1 - 0.0065 15.2 1.1 0.0089 14.7 0.7 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family 3HCDH_N PF02737.13 KLO12337.1 - 0.0091 15.6 1.8 0.013 15.1 0.8 1.6 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.14 KLO12337.1 - 0.024 13.7 0.3 0.036 13.2 0.2 1.2 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Polysacc_synt_2 PF02719.10 KLO12337.1 - 0.034 13.0 1.1 0.054 12.3 0.7 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein adh_short PF00106.20 KLO12338.1 - 3.6e-21 75.8 5.7 3.9e-21 75.7 2.3 2.1 2 1 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.1 KLO12338.1 - 5.1e-21 75.5 1.1 1e-20 74.5 0.7 1.4 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KLO12338.1 - 5.6e-10 39.1 0.1 1.1e-09 38.2 0.1 1.6 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 KLO12338.1 - 0.0044 16.5 0.0 0.0076 15.7 0.0 1.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 KLO12338.1 - 0.081 12.9 1.8 1 9.3 0.6 2.7 2 1 0 2 2 2 0 NADH(P)-binding 3Beta_HSD PF01073.14 KLO12338.1 - 0.12 11.0 0.3 0.18 10.4 0.2 1.3 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.20 KLO12339.1 - 5.2e-24 85.0 0.7 7.8e-24 84.4 0.5 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KLO12339.1 - 2.1e-21 76.8 0.1 2.6e-21 76.5 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KLO12339.1 - 2.6e-09 37.0 0.8 4.3e-09 36.3 0.5 1.2 1 0 0 1 1 1 1 KR domain 3HCDH_N PF02737.13 KLO12339.1 - 0.12 12.0 0.1 0.18 11.4 0.0 1.2 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain CENP-X PF09415.5 KLO12341.1 - 0.098 12.4 0.1 0.2 11.5 0.0 1.4 1 0 0 1 1 1 0 CENP-S associating Centromere protein X p450 PF00067.17 KLO12343.1 - 1.5e-61 208.3 0.0 1.9e-61 208.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 MSC PF09402.5 KLO12344.1 - 0.13 10.9 0.0 0.78 8.3 0.0 2.0 2 0 0 2 2 2 0 Man1-Src1p-C-terminal domain FA_desaturase PF00487.19 KLO12344.1 - 0.17 11.3 4.9 0.041 13.3 1.2 1.5 2 0 0 2 2 2 0 Fatty acid desaturase DUF4131 PF13567.1 KLO12344.1 - 0.37 10.1 3.1 0.77 9.1 2.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) BNR PF02012.15 KLO12347.1 - 2.6e-10 38.5 48.0 0.88 9.6 0.7 12.1 11 0 0 11 11 11 7 BNR/Asp-box repeat Mo-co_dimer PF03404.11 KLO12347.1 - 0.00067 19.2 4.0 1.6 8.3 0.0 5.6 5 1 1 6 6 6 2 Mo-co oxidoreductase dimerisation domain Fe_dep_repr_C PF02742.10 KLO12347.1 - 0.0099 15.5 0.0 0.035 13.7 0.0 1.9 1 0 0 1 1 1 1 Iron dependent repressor, metal binding and dimerisation domain Amidohydro_4 PF13147.1 KLO12348.1 - 1.9e-16 60.9 1.3 2.5e-07 31.0 0.2 2.8 2 1 0 2 2 2 2 Amidohydrolase Amidohydro_1 PF01979.15 KLO12348.1 - 2.7e-14 53.5 0.0 2.7e-11 43.7 0.0 2.3 2 0 0 2 2 2 2 Amidohydrolase family Amidohydro_3 PF07969.6 KLO12348.1 - 3.6e-07 29.7 0.0 6.7e-07 28.8 0.0 1.5 2 0 0 2 2 2 1 Amidohydrolase family Amidohydro_5 PF13594.1 KLO12348.1 - 4.1e-05 23.3 0.0 9.7e-05 22.1 0.0 1.6 1 0 0 1 1 1 1 Amidohydrolase Glyco_hydro_16 PF00722.16 KLO12349.1 - 6.1e-20 71.2 2.9 9.3e-20 70.6 1.0 1.8 1 1 1 2 2 2 1 Glycosyl hydrolases family 16 Acyl-CoA_dh_N PF02771.11 KLO12350.1 - 4.2e-27 94.9 0.0 7.1e-27 94.2 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_1 PF00441.19 KLO12350.1 - 7.1e-27 94.3 0.0 1.1e-26 93.6 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 KLO12350.1 - 5.2e-21 73.8 0.1 3.9e-20 71.0 0.0 2.2 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.6 KLO12350.1 - 1.2e-07 32.0 0.0 1.9e-07 31.4 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain His_Phos_1 PF00300.17 KLO12352.1 - 5.7e-23 81.7 0.0 7.8e-23 81.3 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) SHS2_Rpb7-N PF03876.12 KLO12353.1 - 3e-15 56.0 0.0 4.7e-15 55.4 0.0 1.3 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 S1 PF00575.18 KLO12353.1 - 2.1e-11 43.7 1.1 5.6e-11 42.3 0.8 1.7 1 1 0 1 1 1 1 S1 RNA binding domain RNA_pol_Rbc25 PF08292.7 KLO12353.1 - 0.0082 16.3 0.1 0.016 15.4 0.0 1.6 1 1 0 1 1 1 1 RNA polymerase III subunit Rpc25 MFS_1 PF07690.11 KLO12354.1 - 6.3e-48 163.2 39.2 1.4e-43 148.9 28.5 2.4 2 1 0 2 2 2 2 Major Facilitator Superfamily Aminotran_4 PF01063.14 KLO12355.1 - 2.7e-22 79.4 0.0 3.9e-22 78.8 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class IV SDA1 PF05285.7 KLO12356.1 - 0.0088 15.3 14.4 0.013 14.8 10.0 1.3 1 0 0 1 1 1 1 SDA1 CDC45 PF02724.9 KLO12356.1 - 0.021 12.9 11.3 0.026 12.5 7.8 1.1 1 0 0 1 1 1 0 CDC45-like protein TFIIA PF03153.8 KLO12356.1 - 0.024 14.5 11.4 0.028 14.3 6.8 1.9 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit BUD22 PF09073.5 KLO12356.1 - 0.044 12.8 17.4 0.065 12.2 12.0 1.2 1 0 0 1 1 1 0 BUD22 Nop14 PF04147.7 KLO12356.1 - 0.046 11.6 18.2 0.063 11.1 12.6 1.1 1 0 0 1 1 1 0 Nop14-like family Daxx PF03344.10 KLO12356.1 - 0.096 11.1 17.6 0.14 10.6 12.2 1.2 1 0 0 1 1 1 0 Daxx Family Spore_coat_CotO PF14153.1 KLO12356.1 - 0.2 11.0 8.2 0.34 10.3 5.7 1.3 1 0 0 1 1 1 0 Spore coat protein CotO Trypan_PARP PF05887.6 KLO12356.1 - 0.65 9.8 13.3 1.1 9.0 9.2 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) DUF2201_N PF13203.1 KLO12356.1 - 1.7 7.7 7.2 3.3 6.7 5.0 1.4 1 0 0 1 1 1 0 Putative metallopeptidase domain PPP4R2 PF09184.6 KLO12356.1 - 3.1 7.2 26.0 8.9 5.7 17.6 1.9 2 0 0 2 2 2 0 PPP4R2 DUF913 PF06025.7 KLO12356.1 - 5.7 5.5 7.7 9.1 4.9 5.4 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) FLO_LFY PF01698.11 KLO12356.1 - 6.7 5.4 9.3 11 4.7 6.5 1.3 1 0 0 1 1 1 0 Floricaula / Leafy protein DUF1096 PF06493.6 KLO12357.1 - 0.026 14.4 3.0 0.026 14.4 2.1 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1096) adh_short_C2 PF13561.1 KLO12358.1 - 1.1e-11 45.0 0.2 1.4e-11 44.6 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 KLO12358.1 - 1e-10 41.8 0.1 4.4e-10 39.7 0.1 2.1 2 1 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 KLO12358.1 - 0.00039 20.1 0.0 0.001 18.7 0.0 1.7 2 0 0 2 2 2 1 KR domain NmrA PF05368.8 KLO12358.1 - 0.011 14.9 0.2 0.019 14.2 0.2 1.3 1 0 0 1 1 1 0 NmrA-like family DUF3466 PF11949.3 KLO12358.1 - 0.036 12.6 0.1 0.052 12.1 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3466) adh_short PF00106.20 KLO12359.1 - 3.3e-10 40.1 0.2 5.7e-10 39.3 0.1 1.4 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KLO12359.1 - 1.2e-05 25.2 0.0 1.5e-05 24.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KLO12359.1 - 0.0003 20.5 0.0 0.00053 19.6 0.0 1.4 1 0 0 1 1 1 1 KR domain NmrA PF05368.8 KLO12359.1 - 0.011 14.9 0.2 0.02 14.1 0.2 1.3 1 0 0 1 1 1 0 NmrA-like family adh_short PF00106.20 KLO12360.1 - 5.3e-14 52.4 0.0 1e-13 51.5 0.0 1.5 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KLO12360.1 - 1.1e-09 38.5 0.3 1.4e-09 38.1 0.2 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KLO12360.1 - 2.6e-05 23.9 0.0 5.1e-05 23.0 0.0 1.5 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 KLO12360.1 - 0.0022 17.4 0.3 0.0093 15.4 0.2 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.8 KLO12360.1 - 0.04 13.1 0.1 0.076 12.2 0.1 1.4 1 0 0 1 1 1 0 NmrA-like family Methyltransf_15 PF09445.5 KLO12360.1 - 0.051 13.1 0.2 0.42 10.1 0.1 2.0 1 1 0 1 1 1 0 RNA cap guanine-N2 methyltransferase MFS_1 PF07690.11 KLO12361.1 - 5e-46 157.0 47.5 5e-46 157.0 32.9 2.0 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KLO12361.1 - 4.8e-16 58.3 13.9 4.8e-16 58.3 9.7 3.9 4 0 0 4 4 4 2 Sugar (and other) transporter TRI12 PF06609.8 KLO12361.1 - 2.5e-09 35.8 23.2 3.3e-09 35.5 16.1 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_2 PF13347.1 KLO12361.1 - 0.00017 20.0 4.9 0.00017 20.0 3.4 3.6 2 2 2 4 4 4 1 MFS/sugar transport protein MFS_1 PF07690.11 KLO12362.1 - 1.4e-42 145.7 48.9 1.4e-42 145.7 33.9 2.0 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KLO12362.1 - 1.7e-13 49.9 12.6 1.7e-13 49.9 8.7 3.1 2 1 1 3 3 3 2 Sugar (and other) transporter TRI12 PF06609.8 KLO12362.1 - 2.9e-07 29.0 6.9 2.9e-07 29.0 4.7 1.8 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) PhoD PF09423.5 KLO12363.1 - 6.8e-128 427.0 1.0 8.1e-128 426.8 0.7 1.1 1 0 0 1 1 1 1 PhoD-like phosphatase Hydrophobin PF01185.13 KLO12364.1 - 2e-10 40.9 6.7 2.6e-10 40.5 4.7 1.1 1 0 0 1 1 1 1 Fungal hydrophobin Aldolase_II PF00596.16 KLO12365.1 - 9.6e-37 126.3 0.0 1.2e-36 126.0 0.0 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain bZIP_1 PF00170.16 KLO12367.1 - 1.1e-10 41.3 1.8 1.1e-10 41.3 1.2 2.3 2 0 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.10 KLO12367.1 - 6e-07 29.1 6.4 6e-07 29.1 4.4 2.3 2 0 0 2 2 2 1 Basic region leucine zipper CENP-F_N PF10481.4 KLO12367.1 - 0.0016 17.8 0.9 0.0034 16.7 0.6 1.5 1 0 0 1 1 1 1 Cenp-F N-terminal domain Fmp27_WPPW PF10359.4 KLO12367.1 - 0.013 13.9 0.4 0.02 13.3 0.3 1.2 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain ADIP PF11559.3 KLO12367.1 - 0.052 13.4 7.0 0.088 12.7 4.9 1.3 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding BMFP PF04380.8 KLO12367.1 - 1.1 9.4 10.2 0.6 10.2 0.5 2.9 3 0 0 3 3 3 0 Membrane fusogenic activity bZIP_Maf PF03131.12 KLO12367.1 - 2.1 8.7 11.9 0.44 10.8 0.4 2.4 1 1 1 2 2 2 0 bZIP Maf transcription factor DivIC PF04977.10 KLO12367.1 - 2.1 7.8 7.8 13 5.3 0.1 2.3 1 1 1 2 2 2 0 Septum formation initiator APG6 PF04111.7 KLO12367.1 - 5 6.0 5.7 2.6 7.0 2.4 1.6 2 0 0 2 2 2 0 Autophagy protein Apg6 Peptidase_S10 PF00450.17 KLO12368.1 - 1.9e-87 294.1 0.3 2.4e-87 293.8 0.2 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase zf-MYND PF01753.13 KLO12369.1 - 3e-07 30.2 10.8 3e-07 30.2 7.5 2.0 2 0 0 2 2 2 1 MYND finger Ribosomal_S26e PF01283.14 KLO12370.1 - 1.6e-50 170.1 10.5 1.8e-50 169.9 7.3 1.0 1 0 0 1 1 1 1 Ribosomal protein S26e DUF1918 PF08940.6 KLO12370.1 - 0.016 14.5 0.0 0.033 13.5 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1918) Viral_Beta_CD PF04530.7 KLO12370.1 - 0.068 13.3 0.1 0.081 13.0 0.1 1.1 1 0 0 1 1 1 0 Viral Beta C/D like family Fer4_7 PF12838.2 KLO12370.1 - 0.068 13.5 2.3 0.98 9.8 0.3 2.4 2 1 0 2 2 2 0 4Fe-4S dicluster domain TMF_TATA_bd PF12325.3 KLO12371.1 - 0.026 14.2 9.3 0.057 13.1 0.3 2.9 2 1 1 3 3 3 0 TATA element modulatory factor 1 TATA binding APG6 PF04111.7 KLO12371.1 - 0.37 9.7 10.9 0.39 9.7 2.8 2.2 2 0 0 2 2 2 0 Autophagy protein Apg6 DUF4140 PF13600.1 KLO12371.1 - 1.3 9.5 6.6 18 5.8 0.0 2.9 2 1 1 3 3 3 0 N-terminal domain of unknown function (DUF4140) DUF3713 PF12506.3 KLO12371.1 - 4 7.5 8.0 2.2 8.3 0.6 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3713) DUF2968 PF11180.3 KLO12371.1 - 5.8 6.2 9.8 0.36 10.1 0.1 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF2968) IncA PF04156.9 KLO12372.1 - 1e-06 28.4 0.4 1e-06 28.4 0.3 3.0 1 1 1 3 3 3 1 IncA protein FlgM PF04316.8 KLO12372.1 - 0.0029 17.5 4.8 0.056 13.3 1.0 2.7 2 0 0 2 2 2 1 Anti-sigma-28 factor, FlgM Dpoe2NT PF12213.3 KLO12372.1 - 0.078 12.9 3.0 0.13 12.1 0.7 2.5 2 0 0 2 2 2 0 DNA polymerases epsilon N terminal CRISPR_Cse1 PF09481.5 KLO12372.1 - 0.29 9.8 3.1 0.55 8.9 0.1 2.1 2 0 0 2 2 2 0 CRISPR-associated protein Cse1 (CRISPR_cse1) DUF3810 PF12725.2 KLO12372.1 - 0.67 8.7 5.1 5.5 5.7 0.1 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF3810) TPD52 PF04201.10 KLO12372.1 - 0.87 9.3 10.2 1.2 8.8 2.1 2.7 3 0 0 3 3 3 0 Tumour protein D52 family DUF4200 PF13863.1 KLO12372.1 - 3.3 7.6 24.1 0.44 10.5 3.1 4.0 3 1 1 4 4 4 0 Domain of unknown function (DUF4200) Fib_alpha PF08702.5 KLO12373.1 - 0.00031 20.9 3.4 0.0014 18.7 0.2 2.2 1 1 2 3 3 3 1 Fibrinogen alpha/beta chain family MA3 PF02847.12 KLO12373.1 - 0.02 14.5 1.5 0.087 12.5 0.1 2.2 1 1 1 2 2 2 0 MA3 domain DUF869 PF05911.6 KLO12373.1 - 0.035 12.3 2.8 0.043 12.0 2.0 1.1 1 0 0 1 1 1 0 Plant protein of unknown function (DUF869) DUF2024 PF09630.5 KLO12373.1 - 0.093 12.4 0.4 0.49 10.1 0.1 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF2024) Mitofilin PF09731.4 KLO12373.1 - 0.13 10.9 6.1 0.28 9.8 4.2 1.5 1 1 0 1 1 1 0 Mitochondrial inner membrane protein Med9 PF07544.8 KLO12373.1 - 0.19 11.4 2.8 0.17 11.6 0.4 2.1 2 1 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 DUF87 PF01935.12 KLO12373.1 - 0.54 10.0 3.5 0.27 11.0 0.8 1.6 2 0 0 2 2 2 0 Domain of unknown function DUF87 Syntaxin-6_N PF09177.6 KLO12373.1 - 0.77 10.1 3.7 4.6 7.7 0.1 2.8 2 1 1 3 3 3 0 Syntaxin 6, N-terminal Laminin_II PF06009.7 KLO12373.1 - 1.3 8.8 4.7 9.5 5.9 0.1 2.9 2 1 1 3 3 3 0 Laminin Domain II DUF3347 PF11827.3 KLO12373.1 - 2.9 7.8 5.7 2 8.3 0.2 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3347) DUF2453 PF10507.4 KLO12374.1 - 0.0027 17.4 0.0 0.0031 17.3 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2453) Mating_C PF12737.2 KLO12374.1 - 0.057 12.2 0.0 0.072 11.9 0.0 1.1 1 0 0 1 1 1 0 C-terminal domain of homeodomain 1 Spectrin PF00435.16 KLO12374.1 - 0.077 13.2 0.0 0.1 12.9 0.0 1.1 1 0 0 1 1 1 0 Spectrin repeat Ribosomal_S26e PF01283.14 KLO12375.1 - 3.9e-50 168.8 10.4 4.5e-50 168.6 7.2 1.0 1 0 0 1 1 1 1 Ribosomal protein S26e Ribosomal_S26e PF01283.14 KLO12376.1 - 2.2e-47 160.0 8.3 2.5e-47 159.8 5.8 1.0 1 0 0 1 1 1 1 Ribosomal protein S26e Njmu-R1 PF15053.1 KLO12376.1 - 0.046 12.4 0.0 0.051 12.3 0.0 1.0 1 0 0 1 1 1 0 Mjmu-R1-like protein family DUF4336 PF14234.1 KLO12377.1 - 1.2e-13 50.9 0.0 4.8e-11 42.3 0.0 2.0 2 0 0 2 2 2 2 Domain of unknown function (DUF4336) DUF605 PF04652.11 KLO12379.1 - 0.29 10.5 16.0 0.32 10.3 11.1 1.1 1 0 0 1 1 1 0 Vta1 like Utp14 PF04615.8 KLO12379.1 - 1.5 6.8 7.0 2 6.4 4.8 1.1 1 0 0 1 1 1 0 Utp14 protein NYN PF01936.13 KLO12380.1 - 2.2e-11 44.2 0.0 5.2e-11 43.0 0.0 1.5 2 0 0 2 2 2 1 NYN domain NYN PF01936.13 KLO12381.1 - 9e-08 32.5 0.0 1.6e-07 31.7 0.0 1.3 1 0 0 1 1 1 1 NYN domain Chs3p PF12271.3 KLO12384.1 - 1.3e-52 178.6 7.3 3.1e-52 177.3 5.1 1.5 1 1 0 1 1 1 1 Chitin synthase III catalytic subunit CcmD PF04995.9 KLO12384.1 - 0.18 11.5 4.7 0.24 11.1 0.5 2.7 2 0 0 2 2 2 0 Heme exporter protein D (CcmD) Piwi PF02171.12 KLO12385.1 - 5.9e-74 248.7 0.0 7.8e-74 248.3 0.0 1.1 1 0 0 1 1 1 1 Piwi domain DUF1785 PF08699.5 KLO12385.1 - 5.1e-16 57.7 0.5 2.4e-14 52.4 0.1 2.8 2 0 0 2 2 2 1 Domain of unknown function (DUF1785) PAZ PF02170.17 KLO12385.1 - 4.5e-15 55.1 0.0 8.4e-15 54.2 0.0 1.4 1 0 0 1 1 1 1 PAZ domain Piwi PF02171.12 KLO12386.1 - 2.9e-72 243.1 0.0 3.9e-72 242.7 0.0 1.2 1 0 0 1 1 1 1 Piwi domain PAZ PF02170.17 KLO12386.1 - 9.8e-13 47.5 0.0 2.3e-12 46.3 0.0 1.6 1 0 0 1 1 1 1 PAZ domain DUF1785 PF08699.5 KLO12386.1 - 1.1e-11 43.8 0.0 2.9e-11 42.5 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1785) Glyco_hydro_1 PF00232.13 KLO12387.1 - 2e-157 524.0 0.1 2.5e-157 523.7 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 1 DnaJ PF00226.26 KLO12388.1 - 9e-18 63.7 0.2 1.3e-17 63.2 0.2 1.2 1 0 0 1 1 1 1 DnaJ domain zf-CSL PF05207.8 KLO12388.1 - 1.2e-13 50.3 0.3 2.1e-13 49.5 0.2 1.6 1 0 0 1 1 1 1 CSL zinc finger Amidase PF01425.16 KLO12389.1 - 6.7e-31 107.6 4.0 6.7e-31 107.6 2.8 1.6 2 0 0 2 2 2 1 Amidase Glyco_hydro_1 PF00232.13 KLO12390.1 - 3.9e-151 503.2 0.3 4.7e-151 503.0 0.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 1 Cu-oxidase PF00394.17 KLO12391.1 - 3.3e-39 134.3 0.8 2.2e-33 115.4 0.0 3.1 3 0 0 3 3 3 2 Multicopper oxidase Cu-oxidase_2 PF07731.9 KLO12391.1 - 8.9e-37 125.6 5.1 9.2e-36 122.3 0.1 3.4 3 1 0 3 3 3 1 Multicopper oxidase Cu-oxidase_3 PF07732.10 KLO12391.1 - 3.1e-35 120.4 5.8 2.5e-31 107.8 0.1 4.3 5 0 0 5 5 5 2 Multicopper oxidase DUF2371 PF10177.4 KLO12391.1 - 0.12 12.2 0.0 0.19 11.6 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2371) Abhydrolase_3 PF07859.8 KLO12392.1 - 2.4e-14 53.4 0.1 4.2e-14 52.6 0.0 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.23 KLO12392.1 - 8.5e-09 34.6 0.1 1.9e-08 33.5 0.0 1.4 1 1 0 1 1 1 1 Carboxylesterase family DUF2424 PF10340.4 KLO12392.1 - 1.8e-05 23.5 0.0 2.4e-05 23.1 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2424) Abhydrolase_5 PF12695.2 KLO12392.1 - 3e-05 23.8 0.0 4.1e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KLO12392.1 - 0.011 15.6 0.1 0.034 14.0 0.1 1.4 1 1 0 1 1 1 0 Alpha/beta hydrolase family NACHT PF05729.7 KLO12393.1 - 4.3e-09 36.2 0.1 8.5e-08 32.0 0.0 2.7 2 1 0 2 2 2 1 NACHT domain AAA_16 PF13191.1 KLO12393.1 - 2.9e-05 24.1 4.1 0.0018 18.3 0.1 3.1 3 0 0 3 3 3 2 AAA ATPase domain AAA_22 PF13401.1 KLO12393.1 - 0.0065 16.6 0.7 0.046 13.8 0.0 2.8 3 1 0 3 3 3 1 AAA domain AAA_19 PF13245.1 KLO12393.1 - 0.044 13.5 0.0 0.13 12.0 0.0 1.8 1 0 0 1 1 1 0 Part of AAA domain NB-ARC PF00931.17 KLO12393.1 - 0.05 12.4 0.8 0.22 10.3 0.0 2.1 2 0 0 2 2 2 0 NB-ARC domain AAA_30 PF13604.1 KLO12393.1 - 0.077 12.5 0.0 0.17 11.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain HTH_Crp_2 PF13545.1 KLO12393.1 - 0.081 12.7 2.3 19 5.1 0.0 4.0 4 0 0 4 4 4 0 Crp-like helix-turn-helix domain APS_kinase PF01583.15 KLO12393.1 - 0.085 12.5 0.0 0.18 11.4 0.0 1.5 1 0 0 1 1 1 0 Adenylylsulphate kinase TMEM171 PF15471.1 KLO12395.1 - 0.095 11.4 4.2 0.16 10.7 2.9 1.4 1 0 0 1 1 1 0 Transmembrane protein family 171 Dynamin_N PF00350.18 KLO12396.1 - 2.9e-27 95.5 0.0 1.5e-26 93.1 0.0 2.3 2 1 0 2 2 2 1 Dynamin family Dynamin_M PF01031.15 KLO12396.1 - 2.1e-19 69.4 0.0 8.2e-09 34.6 0.0 2.9 3 0 0 3 3 3 2 Dynamin central region GED PF02212.13 KLO12396.1 - 1.5e-10 40.8 0.9 3.7e-10 39.5 0.6 1.7 1 0 0 1 1 1 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.18 KLO12396.1 - 0.00018 21.4 0.0 0.0031 17.4 0.0 2.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 KLO12396.1 - 0.016 15.6 0.0 0.035 14.6 0.0 1.6 1 0 0 1 1 1 0 Miro-like protein AAA_28 PF13521.1 KLO12396.1 - 0.048 13.6 2.8 0.053 13.4 0.0 2.5 3 0 0 3 3 3 0 AAA domain PDE8 PF08629.5 KLO12398.1 - 0.092 12.5 0.1 0.21 11.3 0.1 1.6 1 0 0 1 1 1 0 PDE8 phosphodiesterase DUF1459 PF07312.6 KLO12398.1 - 0.91 9.4 4.4 1.7 8.6 0.6 3.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1459) Dynamin_N PF00350.18 KLO12399.1 - 7.7e-25 87.6 0.0 2.2e-24 86.1 0.0 1.8 1 1 0 1 1 1 1 Dynamin family Dynamin_M PF01031.15 KLO12399.1 - 1.1e-22 80.2 0.0 2e-10 39.9 0.0 2.9 3 0 0 3 3 3 2 Dynamin central region GED PF02212.13 KLO12399.1 - 1.2e-11 44.2 2.2 3.2e-11 42.9 1.6 1.7 1 0 0 1 1 1 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.18 KLO12399.1 - 0.00047 20.1 0.0 0.0038 17.1 0.0 2.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 KLO12399.1 - 0.021 15.3 0.0 0.092 13.2 0.0 2.1 2 0 0 2 2 2 0 Miro-like protein Methyltransf_1N PF02870.10 KLO12399.1 - 0.054 14.0 0.0 0.14 12.7 0.0 1.7 1 0 0 1 1 1 0 6-O-methylguanine DNA methyltransferase, ribonuclease-like domain AAA_28 PF13521.1 KLO12399.1 - 0.073 13.0 0.1 0.21 11.5 0.0 1.8 1 0 0 1 1 1 0 AAA domain CBM_3 PF00942.13 KLO12401.1 - 0.038 14.0 0.0 0.067 13.2 0.0 1.3 1 0 0 1 1 1 0 Cellulose binding domain DUF2784 PF10861.3 KLO12410.1 - 7.4 6.3 10.6 0.47 10.2 1.7 2.9 3 1 0 3 3 3 0 Protein of Unknown function (DUF2784) TraC_F_IV PF11130.3 KLO12412.1 - 0.083 12.3 0.9 3.8 6.8 0.0 2.5 1 1 2 3 3 3 0 F pilus assembly Type-IV secretion system for plasmid transfer Baculo_PEP_C PF04513.7 KLO12412.1 - 0.19 11.5 6.1 2.8 7.7 0.1 3.1 4 0 0 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus RP-C_C PF11800.3 KLO12412.1 - 0.35 10.5 4.9 0.15 11.7 1.2 1.9 2 0 0 2 2 2 0 Replication protein C C-terminal region NACHT PF05729.7 KLO12413.1 - 3.3e-11 43.1 0.4 9.5e-11 41.6 0.3 1.7 1 1 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 KLO12413.1 - 5.3e-05 23.2 0.3 0.00029 20.8 0.2 1.9 1 1 0 1 1 1 1 AAA ATPase domain NB-ARC PF00931.17 KLO12413.1 - 0.00015 20.7 0.0 0.00019 20.3 0.0 1.1 1 0 0 1 1 1 1 NB-ARC domain AAA_22 PF13401.1 KLO12413.1 - 0.0012 18.9 0.0 0.0022 18.1 0.0 1.4 1 1 0 1 1 1 1 AAA domain Thymidylate_kin PF02223.12 KLO12413.1 - 0.015 14.7 0.0 0.025 13.9 0.0 1.3 1 0 0 1 1 1 0 Thymidylate kinase AAA_14 PF13173.1 KLO12413.1 - 0.019 14.8 0.0 0.75 9.7 0.0 2.1 1 1 0 1 1 1 0 AAA domain APS_kinase PF01583.15 KLO12413.1 - 0.033 13.8 0.1 0.05 13.2 0.0 1.2 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA PF00004.24 KLO12413.1 - 0.038 14.1 0.0 0.084 13.0 0.0 1.5 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Parvo_NS1 PF01057.12 KLO12413.1 - 0.075 11.8 0.0 0.1 11.4 0.0 1.1 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_17 PF13207.1 KLO12413.1 - 0.15 12.9 0.1 0.24 12.2 0.1 1.5 1 1 0 1 1 1 0 AAA domain zf-MYND PF01753.13 KLO12414.1 - 3.5e-11 42.7 15.2 3.5e-11 42.7 10.5 2.3 2 0 0 2 2 2 1 MYND finger zf-Mss51 PF13824.1 KLO12414.1 - 0.067 13.0 5.4 0.18 11.6 3.8 1.7 1 0 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 DUF1924 PF09086.6 KLO12414.1 - 0.11 12.5 2.1 0.3 11.1 1.4 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1924) CFEM PF05730.6 KLO12418.1 - 3.3e-08 33.2 10.5 5.5e-08 32.5 7.2 1.3 1 0 0 1 1 1 1 CFEM domain CFEM PF05730.6 KLO12420.1 - 9.9e-09 34.9 14.5 1.7e-08 34.1 10.0 1.4 1 0 0 1 1 1 1 CFEM domain Plasmodium_Vir PF05795.6 KLO12420.1 - 0.14 11.3 1.0 0.17 11.0 0.7 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Macoilin PF09726.4 KLO12420.1 - 7 4.8 13.1 8.3 4.5 9.1 1.1 1 0 0 1 1 1 0 Transmembrane protein UPF0126 PF03458.8 KLO12420.1 - 9.9 5.8 9.4 2.3 7.8 4.1 1.8 2 0 0 2 2 2 0 UPF0126 domain CFEM PF05730.6 KLO12424.1 - 2.5e-08 33.6 14.5 4.1e-08 32.9 10.1 1.3 1 0 0 1 1 1 1 CFEM domain zf-MYND PF01753.13 KLO12425.1 - 2.5e-10 40.0 15.2 5.1e-10 39.0 10.5 1.5 1 0 0 1 1 1 1 MYND finger zf-Mss51 PF13824.1 KLO12425.1 - 0.42 10.5 6.1 0.96 9.3 4.3 1.6 1 0 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 NACHT PF05729.7 KLO12427.1 - 7.4e-08 32.2 0.0 2.9e-07 30.3 0.0 2.1 1 0 0 1 1 1 1 NACHT domain AAA PF00004.24 KLO12427.1 - 0.0031 17.7 0.0 0.014 15.5 0.0 2.2 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.1 KLO12427.1 - 0.01 15.5 0.0 0.049 13.3 0.0 2.2 2 0 0 2 2 1 0 Part of AAA domain AAA_22 PF13401.1 KLO12427.1 - 0.012 15.7 0.0 0.084 13.0 0.0 2.5 3 0 0 3 3 3 0 AAA domain AAA_17 PF13207.1 KLO12427.1 - 0.016 16.0 0.8 0.22 12.3 0.1 3.1 1 1 1 2 2 2 0 AAA domain HTH_20 PF12840.2 KLO12427.1 - 0.023 14.4 0.1 0.078 12.7 0.1 1.9 1 0 0 1 1 1 0 Helix-turn-helix domain MarR_2 PF12802.2 KLO12427.1 - 0.029 14.0 0.5 0.079 12.6 0.3 1.7 1 0 0 1 1 1 0 MarR family AAA_30 PF13604.1 KLO12427.1 - 0.059 12.9 0.0 0.12 11.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain APS_kinase PF01583.15 KLO12427.1 - 0.061 12.9 0.1 0.16 11.6 0.1 1.7 1 0 0 1 1 1 0 Adenylylsulphate kinase NB-ARC PF00931.17 KLO12427.1 - 0.082 11.7 0.0 0.18 10.6 0.0 1.7 1 0 0 1 1 1 0 NB-ARC domain PhoH PF02562.11 KLO12427.1 - 0.091 11.9 0.0 0.16 11.2 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein NACHT PF05729.7 KLO12430.1 - 5.8e-07 29.3 0.1 1.5e-06 27.9 0.0 1.7 1 1 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 KLO12430.1 - 0.00027 20.9 1.1 0.0036 17.3 0.1 3.3 3 1 0 3 3 3 1 AAA ATPase domain AAA_22 PF13401.1 KLO12430.1 - 0.005 16.9 0.0 0.032 14.3 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA PF00004.24 KLO12430.1 - 0.0069 16.5 0.0 0.02 15.0 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.1 KLO12430.1 - 0.0095 15.6 0.0 0.077 12.7 0.0 2.6 3 0 0 3 3 3 1 Part of AAA domain NB-ARC PF00931.17 KLO12430.1 - 0.028 13.2 0.0 0.069 11.9 0.0 1.7 2 0 0 2 2 2 0 NB-ARC domain AAA_30 PF13604.1 KLO12430.1 - 0.035 13.7 0.0 0.072 12.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.1 KLO12430.1 - 0.047 14.5 0.0 0.21 12.3 0.0 2.2 1 0 0 1 1 1 0 AAA domain APS_kinase PF01583.15 KLO12430.1 - 0.1 12.2 0.1 0.22 11.1 0.0 1.5 1 0 0 1 1 1 0 Adenylylsulphate kinase PhoH PF02562.11 KLO12430.1 - 0.13 11.4 0.0 0.24 10.6 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein F-box-like PF12937.2 KLO12432.1 - 1e-05 25.1 0.1 2.3e-05 24.0 0.1 1.6 1 0 0 1 1 1 1 F-box-like PHB_acc_N PF07879.6 KLO12432.1 - 0.025 14.3 0.0 1.4 8.6 0.0 2.6 2 1 0 2 2 2 0 PHB/PHA accumulation regulator DNA-binding domain Tir_receptor_C PF07489.6 KLO12433.1 - 0.23 11.1 6.9 0.37 10.5 4.8 1.3 1 0 0 1 1 1 0 Translocated intimin receptor (Tir) C-terminus SpvB PF03534.8 KLO12437.1 - 1.1e-12 47.6 5.0 8.2e-09 34.8 1.7 3.2 1 1 1 2 2 2 2 Salmonella virulence plasmid 65kDa B protein DEAD PF00270.24 KLO12440.1 - 1.5e-10 40.8 0.0 4.1e-10 39.4 0.0 1.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KLO12440.1 - 8.4e-09 35.1 0.0 2.1e-08 33.8 0.0 1.7 2 0 0 2 2 2 1 Helicase conserved C-terminal domain Aminotran_MocR PF12897.2 KLO12440.1 - 0.21 10.0 0.0 0.33 9.4 0.0 1.2 1 0 0 1 1 1 0 Alanine-glyoxylate amino-transferase WD40 PF00400.27 KLO12441.1 - 0.04 13.8 0.0 0.19 11.6 0.0 2.2 2 0 0 2 2 2 0 WD domain, G-beta repeat Mito_carr PF00153.22 KLO12442.1 - 4.7e-55 183.2 0.4 9e-19 66.9 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Baculo_PEP_C PF04513.7 KLO12446.1 - 0.02 14.7 1.3 0.043 13.6 0.3 1.8 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus NPV_P10 PF05531.7 KLO12451.1 - 0.00049 20.2 8.2 0.00098 19.3 4.7 2.2 2 1 0 2 2 2 1 Nucleopolyhedrovirus P10 protein Baculo_PEP_C PF04513.7 KLO12451.1 - 0.0018 18.1 3.8 0.0062 16.3 2.5 2.0 1 1 0 1 1 1 1 Baculovirus polyhedron envelope protein, PEP, C terminus LUC7 PF03194.10 KLO12451.1 - 0.0022 17.5 1.0 0.0027 17.2 0.7 1.2 1 0 0 1 1 1 1 LUC7 N_terminus DUF948 PF06103.6 KLO12451.1 - 0.0067 16.2 5.0 0.013 15.3 2.1 2.4 2 1 0 2 2 2 1 Bacterial protein of unknown function (DUF948) Reo_sigmaC PF04582.7 KLO12451.1 - 0.012 14.8 1.2 0.015 14.5 0.8 1.2 1 0 0 1 1 1 0 Reovirus sigma C capsid protein AAA_13 PF13166.1 KLO12451.1 - 0.018 13.5 1.7 0.026 13.0 1.2 1.2 1 0 0 1 1 1 0 AAA domain Laminin_II PF06009.7 KLO12451.1 - 0.018 14.7 4.5 0.055 13.2 2.3 2.3 2 1 1 3 3 3 0 Laminin Domain II DUF2730 PF10805.3 KLO12451.1 - 0.025 14.2 3.1 0.1 12.3 0.3 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF2730) Prominin PF05478.6 KLO12451.1 - 0.028 11.9 0.8 0.034 11.6 0.6 1.1 1 0 0 1 1 1 0 Prominin V_ATPase_I PF01496.14 KLO12451.1 - 0.032 12.1 0.8 0.04 11.7 0.6 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family ApoLp-III PF07464.6 KLO12451.1 - 0.036 14.0 1.5 0.076 13.0 1.1 1.5 1 1 0 1 1 1 0 Apolipophorin-III precursor (apoLp-III) DUF1679 PF07914.6 KLO12451.1 - 0.042 12.4 0.3 0.056 12.0 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) ISG65-75 PF11727.3 KLO12451.1 - 0.046 12.7 0.4 0.067 12.2 0.3 1.2 1 0 0 1 1 1 0 Invariant surface glycoprotein DUF3450 PF11932.3 KLO12451.1 - 0.048 12.9 0.6 0.056 12.7 0.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) Nup54 PF13874.1 KLO12451.1 - 0.05 13.2 0.2 0.098 12.3 0.2 1.6 1 1 0 1 1 1 0 Nucleoporin complex subunit 54 IncA PF04156.9 KLO12451.1 - 0.079 12.5 0.7 0.12 11.9 0.5 1.4 1 0 0 1 1 1 0 IncA protein DUF1664 PF07889.7 KLO12451.1 - 0.098 12.4 3.5 0.92 9.3 2.1 2.6 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) Phasin PF05597.6 KLO12451.1 - 0.099 12.4 3.0 0.13 11.9 1.4 1.7 2 0 0 2 2 2 0 Poly(hydroxyalcanoate) granule associated protein (phasin) Spectrin PF00435.16 KLO12451.1 - 0.1 12.9 0.3 0.21 11.8 0.2 1.6 1 0 0 1 1 1 0 Spectrin repeat Cauli_DNA-bind PF03310.8 KLO12451.1 - 0.1 12.4 0.3 0.16 11.7 0.2 1.4 1 0 0 1 1 1 0 Caulimovirus DNA-binding protein DUF1542 PF07564.6 KLO12451.1 - 0.11 12.5 4.6 0.13 12.3 2.4 1.7 1 1 1 2 2 2 0 Domain of Unknown Function (DUF1542) SNARE PF05739.14 KLO12451.1 - 0.13 11.9 2.9 0.25 11.0 1.0 2.1 1 1 0 1 1 1 0 SNARE domain Seryl_tRNA_N PF02403.17 KLO12451.1 - 0.21 11.5 2.7 0.28 11.2 0.2 2.3 2 1 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain SlyX PF04102.7 KLO12451.1 - 0.31 11.4 2.1 0.73 10.2 1.1 1.9 1 1 0 1 1 1 0 SlyX Syntaxin PF00804.20 KLO12451.1 - 0.5 10.5 4.3 1.2 9.3 2.4 2.0 2 1 0 2 2 2 0 Syntaxin BLOC1_2 PF10046.4 KLO12451.1 - 0.69 10.0 4.2 1.8 8.7 2.4 2.1 1 1 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF848 PF05852.6 KLO12451.1 - 1.3 8.8 4.5 2.2 8.1 1.1 2.2 1 1 0 1 1 1 0 Gammaherpesvirus protein of unknown function (DUF848) VHS PF00790.14 KLO12452.1 - 2e-29 102.0 0.1 9.7e-29 99.8 0.0 2.1 2 1 0 2 2 2 1 VHS domain GAT PF03127.9 KLO12452.1 - 1.5e-19 69.8 0.2 1.5e-19 69.8 0.1 2.0 2 0 0 2 2 2 1 GAT domain DUF812 PF05667.6 KLO12452.1 - 0.022 13.2 2.4 0.24 9.8 1.6 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF812) FA PF08736.6 KLO12452.1 - 0.086 12.6 0.0 0.18 11.5 0.0 1.6 1 0 0 1 1 1 0 FERM adjacent (FA) DUF619 PF04768.8 KLO12453.1 - 1.2e-36 125.6 0.0 3.2e-26 91.7 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF619) Semialdhyde_dh PF01118.19 KLO12453.1 - 3.5e-25 88.6 0.0 8.2e-25 87.4 0.0 1.7 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain AA_kinase PF00696.23 KLO12453.1 - 4e-20 72.3 0.2 1.4e-19 70.6 0.0 2.0 2 0 0 2 2 2 1 Amino acid kinase family Lectin_N PF03954.9 KLO12454.1 - 0.11 11.9 0.2 0.23 10.8 0.1 1.5 1 0 0 1 1 1 0 Hepatic lectin, N-terminal domain DUF2524 PF10732.4 KLO12454.1 - 0.47 10.6 5.2 4.5 7.4 0.6 3.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2524) Ax_dynein_light PF10211.4 KLO12454.1 - 8 6.2 10.3 0.22 11.3 1.8 2.2 2 0 0 2 2 2 0 Axonemal dynein light chain IMD PF08397.6 KLO12455.1 - 0.58 9.4 3.4 0.25 10.6 0.3 1.8 2 0 0 2 2 2 0 IRSp53/MIM homology domain IMD PF08397.6 KLO12456.1 - 0.42 9.8 4.6 0.19 10.9 0.6 2.0 2 0 0 2 2 2 0 IRSp53/MIM homology domain SpoOE-like PF09388.5 KLO12456.1 - 1 8.9 3.8 1.7 8.1 0.1 2.5 2 0 0 2 2 2 0 Spo0E like sporulation regulatory protein DUF4094 PF13334.1 KLO12456.1 - 5.3 7.4 6.2 0.79 10.1 1.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4094) Catalase PF00199.14 KLO12458.1 - 5e-181 601.4 0.5 6.4e-181 601.1 0.3 1.0 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.7 KLO12458.1 - 2e-16 59.5 0.4 4.8e-16 58.3 0.0 1.8 2 0 0 2 2 2 1 Catalase-related immune-responsive RA PF00788.18 KLO12459.1 - 2.4e-14 53.5 2.0 5.2e-11 42.8 0.0 4.6 4 1 0 4 4 4 1 Ras association (RalGDS/AF-6) domain SH3_1 PF00018.23 KLO12459.1 - 6.1e-06 25.5 0.0 1.3e-05 24.4 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 KLO12459.1 - 0.00031 20.2 0.0 0.00064 19.2 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain F-box PF00646.28 KLO12460.1 - 1.2e-05 24.8 0.7 2.9e-05 23.5 0.5 1.7 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 KLO12460.1 - 3.1e-05 23.6 1.8 9.1e-05 22.1 0.2 2.3 2 0 0 2 2 2 1 F-box-like RRM_1 PF00076.17 KLO12461.1 - 2.8e-14 52.4 0.0 4.5e-14 51.8 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KLO12461.1 - 1.3e-13 50.7 0.0 2.2e-13 49.9 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KLO12461.1 - 3.6e-11 42.7 0.0 5.5e-11 42.1 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Hydrophobin PF01185.13 KLO12462.1 - 5.7e-15 55.5 10.3 7.3e-15 55.1 7.1 1.1 1 0 0 1 1 1 1 Fungal hydrophobin Granulin PF00396.13 KLO12462.1 - 0.47 10.6 7.0 0.62 10.2 0.6 2.2 2 0 0 2 2 2 0 Granulin PI3_PI4_kinase PF00454.22 KLO12463.1 - 0.15 11.5 0.2 0.29 10.5 0.1 1.5 1 0 0 1 1 1 0 Phosphatidylinositol 3- and 4-kinase NfeD PF01957.13 KLO12468.1 - 3.5 7.7 8.3 7.4 6.6 5.8 1.7 1 1 0 1 1 1 0 NfeD-like C-terminal, partner-binding Baculo_PEP_C PF04513.7 KLO12469.1 - 0.049 13.4 13.8 6.9 6.4 2.5 2.7 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus FlxA PF14282.1 KLO12469.1 - 0.051 13.5 2.1 0.07 13.0 1.5 1.2 1 0 0 1 1 1 0 FlxA-like protein DUF1700 PF08006.6 KLO12469.1 - 0.059 12.6 2.0 0.092 12.0 1.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1700) SurA_N PF09312.6 KLO12469.1 - 0.1 12.4 0.5 0.15 11.9 0.3 1.2 1 0 0 1 1 1 0 SurA N-terminal domain ETRAMP PF09716.5 KLO12469.1 - 1.1 9.3 5.7 7.8 6.5 3.9 2.2 1 1 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) DUF4349 PF14257.1 KLO12469.1 - 8.4 5.5 10.0 1.9 7.6 2.5 2.6 1 1 2 3 3 3 0 Domain of unknown function (DUF4349) Baculo_PEP_C PF04513.7 KLO12471.1 - 0.00063 19.5 10.2 0.028 14.2 1.5 2.4 1 1 1 2 2 2 2 Baculovirus polyhedron envelope protein, PEP, C terminus FlxA PF14282.1 KLO12471.1 - 0.03 14.2 3.3 0.04 13.8 2.3 1.1 1 0 0 1 1 1 0 FlxA-like protein DUF1700 PF08006.6 KLO12471.1 - 0.058 12.7 2.5 0.09 12.0 1.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1700) ERCC4 PF02732.10 KLO12474.1 - 7.2e-26 90.6 0.0 1.4e-25 89.6 0.0 1.5 1 0 0 1 1 1 1 ERCC4 domain MFS_1 PF07690.11 KLO12475.1 - 1.1e-19 70.3 53.4 1e-13 50.7 21.9 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily WD40 PF00400.27 KLO12478.1 - 1.4e-13 50.1 0.0 0.00013 21.6 0.0 5.1 5 0 0 5 5 5 2 WD domain, G-beta repeat F-box-like PF12937.2 KLO12478.1 - 9.1e-08 31.7 4.0 6.8e-07 28.9 0.2 2.4 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 KLO12478.1 - 2.9e-05 23.5 1.2 0.00033 20.2 0.1 2.4 2 0 0 2 2 2 1 F-box domain PQQ_2 PF13360.1 KLO12478.1 - 0.0026 17.2 0.1 1.4 8.2 0.2 2.7 1 1 1 2 2 2 2 PQQ-like domain Beach PF02138.13 KLO12479.1 - 1.1e-96 323.3 0.0 2.2e-96 322.4 0.0 1.5 1 0 0 1 1 1 1 Beige/BEACH domain WD40 PF00400.27 KLO12479.1 - 6.3e-12 44.8 10.5 0.0025 17.6 0.4 5.6 5 0 0 5 5 5 3 WD domain, G-beta repeat Laminin_G_3 PF13385.1 KLO12479.1 - 3.3e-10 40.4 0.0 8.3e-10 39.1 0.0 1.7 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily PH_BEACH PF14844.1 KLO12479.1 - 1.5e-08 34.4 0.0 4.9e-08 32.7 0.0 2.0 1 0 0 1 1 1 1 PH domain associated with Beige/BEACH FHA PF00498.21 KLO12480.1 - 1.5e-15 57.0 0.0 3.2e-15 56.0 0.0 1.6 1 0 0 1 1 1 1 FHA domain zf-RING_2 PF13639.1 KLO12480.1 - 3.8e-07 29.8 14.4 6.1e-07 29.1 10.0 1.3 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 KLO12480.1 - 0.00068 19.7 4.8 0.0013 18.7 3.4 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger zf-Apc11 PF12861.2 KLO12480.1 - 0.017 14.9 5.0 0.03 14.1 3.5 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4 PF00097.20 KLO12480.1 - 0.039 13.6 12.8 0.066 12.8 8.9 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KLO12480.1 - 0.045 13.4 12.1 0.084 12.6 8.4 1.4 1 0 0 1 1 1 0 zinc-RING finger domain zf-C3HC4_3 PF13920.1 KLO12480.1 - 0.12 12.0 11.0 0.21 11.3 7.6 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KLO12480.1 - 1.9 8.6 15.5 3.2 7.8 10.8 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) PHD PF00628.24 KLO12480.1 - 4.2 7.1 8.7 8.1 6.2 6.0 1.4 1 0 0 1 1 1 0 PHD-finger Peptidase_S41 PF03572.13 KLO12481.1 - 0.0061 15.9 0.0 0.013 14.8 0.0 1.7 1 1 0 1 1 1 1 Peptidase family S41 DUF1308 PF07000.6 KLO12482.1 - 7.9e-28 97.1 0.0 6.8e-27 94.0 0.0 2.5 1 1 0 1 1 1 1 Protein of unknown function (DUF1308) SPC12 PF06645.8 KLO12484.1 - 1.3e-22 79.4 0.1 1.4e-22 79.2 0.0 1.1 1 0 0 1 1 1 1 Microsomal signal peptidase 12 kDa subunit (SPC12) S1-P1_nuclease PF02265.11 KLO12485.1 - 9.1e-72 241.7 0.0 7.8e-71 238.6 0.0 1.9 1 1 0 1 1 1 1 S1/P1 Nuclease ERbeta_N PF12497.3 KLO12485.1 - 0.1 12.4 0.0 0.2 11.5 0.0 1.5 1 0 0 1 1 1 0 Estrogen receptor beta Rho_GDI PF02115.12 KLO12486.1 - 7 6.0 13.4 6.8 6.0 2.4 2.2 2 0 0 2 2 2 0 RHO protein GDP dissociation inhibitor zf-rbx1 PF12678.2 KLO12487.1 - 5.2e-35 119.3 13.9 6.5e-35 119.0 9.6 1.1 1 0 0 1 1 1 1 RING-H2 zinc finger zf-Apc11 PF12861.2 KLO12487.1 - 2.1e-17 62.7 9.7 2.9e-17 62.2 6.7 1.2 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_2 PF13639.1 KLO12487.1 - 2.5e-07 30.3 11.8 1.2e-06 28.2 8.2 1.9 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 KLO12487.1 - 0.00069 19.2 12.0 0.017 14.7 8.3 2.7 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KLO12487.1 - 0.0024 17.5 9.7 0.24 11.0 6.9 2.4 1 1 1 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KLO12487.1 - 0.021 14.8 12.1 0.58 10.2 8.4 2.3 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) FANCL_C PF11793.3 KLO12487.1 - 0.87 9.5 10.0 5.9 6.9 7.0 2.0 1 1 1 2 2 2 0 FANCL C-terminal domain zf-RING_UBOX PF13445.1 KLO12487.1 - 1.3 8.8 7.5 44 3.9 5.2 2.3 1 1 0 1 1 1 0 RING-type zinc-finger zf-RING_5 PF14634.1 KLO12487.1 - 1.7 8.4 11.6 20 5.0 8.0 2.5 1 1 0 1 1 1 0 zinc-RING finger domain zf-HC5HC2H PF13771.1 KLO12487.1 - 1.9 8.6 10.7 1.6e+02 2.5 7.5 2.2 1 1 0 1 1 1 0 PHD-like zinc-binding domain TBCC PF07986.7 KLO12488.1 - 8.7e-20 70.3 0.6 2.5e-19 68.8 0.3 1.9 1 1 1 2 2 2 1 Tubulin binding cofactor C Flagellin_N PF00669.15 KLO12488.1 - 0.008 15.9 0.9 0.018 14.8 0.0 1.9 1 1 1 2 2 2 1 Bacterial flagellin N-terminal helical region HMGL-like PF00682.14 KLO12489.1 - 1.2e-47 162.5 0.2 5.8e-47 160.3 0.1 1.8 1 1 0 1 1 1 1 HMGL-like SKG6 PF08693.5 KLO12490.1 - 0.019 14.3 0.0 0.043 13.1 0.0 1.6 1 0 0 1 1 1 0 Transmembrane alpha-helix domain DUF4448 PF14610.1 KLO12490.1 - 0.1 12.0 0.0 0.23 10.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) Abhydrolase_6 PF12697.2 KLO12491.1 - 2.1e-20 73.6 0.6 3.6e-20 72.8 0.4 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KLO12491.1 - 7e-06 25.7 0.0 2.4e-05 24.0 0.0 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KLO12491.1 - 0.00018 21.2 0.0 0.00065 19.4 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 KLO12491.1 - 0.00037 19.7 0.0 0.0011 18.2 0.0 1.7 2 0 0 2 2 2 1 Prolyl oligopeptidase family PAF-AH_p_II PF03403.8 KLO12491.1 - 0.0035 15.7 0.0 0.005 15.1 0.0 1.1 1 0 0 1 1 1 1 Platelet-activating factor acetylhydrolase, isoform II Esterase PF00756.15 KLO12491.1 - 0.024 14.0 0.0 0.038 13.4 0.0 1.3 1 0 0 1 1 1 0 Putative esterase Dot_icm_IcmQ PF09475.5 KLO12491.1 - 0.073 12.3 0.0 0.12 11.6 0.0 1.2 1 0 0 1 1 1 0 Dot/Icm secretion system protein (dot_icm_IcmQ) Metallophos PF00149.23 KLO12492.1 - 1.3e-10 41.0 2.3 2.1e-10 40.3 1.6 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase DUF775 PF05603.7 KLO12493.1 - 4.3e-44 150.4 0.0 5.9e-44 150.0 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF775) SET PF00856.23 KLO12494.1 - 4.7e-24 85.5 0.1 4.7e-24 85.5 0.0 2.2 2 1 0 2 2 2 1 SET domain N-SET PF11764.3 KLO12494.1 - 5.8e-10 39.3 0.4 5.8e-10 39.3 0.3 3.5 3 0 0 3 3 3 1 COMPASS (Complex proteins associated with Set1p) component N RRM_1 PF00076.17 KLO12494.1 - 4.9e-09 35.6 0.0 5.4e-07 29.1 0.0 2.7 2 1 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KLO12494.1 - 1.1e-05 25.3 0.0 0.13 12.2 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) SET_assoc PF11767.3 KLO12494.1 - 0.0016 17.6 0.1 0.0084 15.4 0.0 2.1 2 0 0 2 2 2 1 Histone lysine methyltransferase SET associated RRM_5 PF13893.1 KLO12494.1 - 0.029 14.2 0.0 11 5.9 0.0 2.6 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) ABC_tran PF00005.22 KLO12495.1 - 5.1e-22 78.6 0.0 1.1e-21 77.5 0.0 1.6 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 KLO12495.1 - 1.2e-08 35.2 0.0 0.0016 18.4 0.0 2.6 1 1 0 2 2 2 2 AAA domain SMC_N PF02463.14 KLO12495.1 - 9.9e-06 24.9 0.1 0.13 11.4 0.0 2.4 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 KLO12495.1 - 0.015 14.7 0.0 0.039 13.4 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_23 PF13476.1 KLO12495.1 - 0.024 14.9 0.5 0.078 13.2 0.1 1.9 1 1 0 2 2 2 0 AAA domain DUF258 PF03193.11 KLO12495.1 - 0.035 13.3 0.0 0.064 12.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_16 PF13191.1 KLO12495.1 - 0.038 13.9 0.0 0.092 12.7 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.1 KLO12495.1 - 0.12 12.5 0.0 0.39 10.8 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.1 KLO12495.1 - 0.15 11.6 0.0 0.43 10.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain Leader_Thr PF08254.6 KLO12498.1 - 0.031 13.8 0.2 0.067 12.8 0.2 1.6 1 0 0 1 1 1 0 Threonine leader peptide Tim54 PF11711.3 KLO12498.1 - 7 5.1 10.2 8.9 4.7 7.1 1.2 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 CPDase PF07823.6 KLO12499.1 - 3.8e-16 59.1 0.1 1.4e-15 57.2 0.1 1.7 1 1 0 1 1 1 1 Cyclic phosphodiesterase-like protein 2_5_RNA_ligase2 PF13563.1 KLO12499.1 - 0.0025 17.5 0.0 0.0033 17.1 0.0 1.2 1 0 0 1 1 1 1 2'-5' RNA ligase superfamily LigT_PEase PF02834.11 KLO12499.1 - 0.0052 16.7 0.0 0.0088 16.0 0.0 1.4 1 0 0 1 1 1 1 LigT like Phosphoesterase Ras PF00071.17 KLO12500.1 - 1.1e-52 177.6 0.0 1.3e-52 177.4 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KLO12500.1 - 3.8e-15 56.4 0.0 5e-15 56.0 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KLO12500.1 - 1.3e-07 31.0 0.0 3.3e-07 29.7 0.0 1.6 1 1 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 KLO12500.1 - 0.00028 20.0 0.0 0.00037 19.6 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Arch_ATPase PF01637.13 KLO12500.1 - 0.099 12.3 0.0 0.14 11.8 0.0 1.2 1 0 0 1 1 1 0 Archaeal ATPase Bestrophin PF01062.16 KLO12501.1 - 5.8e-45 153.4 0.9 2.6e-26 92.2 0.1 2.1 2 0 0 2 2 2 2 Bestrophin, RFP-TM, chloride channel tRNA-synt_2b PF00587.20 KLO12502.1 - 5.3e-37 127.0 0.0 1e-36 126.0 0.0 1.5 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.17 KLO12502.1 - 6.8e-15 55.0 7.9 1.2e-14 54.1 5.5 1.4 1 0 0 1 1 1 1 Seryl-tRNA synthetase N-terminal domain CARD PF00619.16 KLO12502.1 - 0.033 14.0 0.2 3.5 7.5 0.0 2.6 2 0 0 2 2 2 0 Caspase recruitment domain Peptidase_M61 PF05299.7 KLO12502.1 - 0.042 13.8 0.1 4 7.4 0.0 2.4 2 0 0 2 2 2 0 M61 glycyl aminopeptidase WD40 PF00400.27 KLO12503.1 - 2.6e-08 33.4 9.0 0.0053 16.5 0.3 4.3 5 0 0 5 5 5 3 WD domain, G-beta repeat PSII_BNR PF14870.1 KLO12503.1 - 0.0088 15.0 0.0 0.025 13.6 0.0 1.8 2 0 0 2 2 2 1 Photosynthesis system II assembly factor YCF48 RR_TM4-6 PF06459.7 KLO12503.1 - 0.25 11.1 8.7 0.45 10.3 6.1 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 BUD22 PF09073.5 KLO12503.1 - 1.8 7.5 24.6 2.7 6.9 17.1 1.2 1 0 0 1 1 1 0 BUD22 CDC45 PF02724.9 KLO12503.1 - 7.3 4.4 19.9 10 4.0 13.8 1.1 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.7 KLO12503.1 - 8.8 4.1 22.1 12 3.6 15.3 1.1 1 0 0 1 1 1 0 Nop14-like family STAG PF08514.6 KLO12504.1 - 3.6e-29 100.8 0.6 1.6e-28 98.7 0.1 2.5 2 0 0 2 2 2 1 STAG domain HEAT_2 PF13646.1 KLO12504.1 - 8.1e-06 26.0 0.0 0.00013 22.1 0.0 3.1 2 1 1 3 3 3 2 HEAT repeats HEAT PF02985.17 KLO12504.1 - 0.0019 18.1 2.3 20 5.6 0.0 5.7 6 0 0 6 6 6 1 HEAT repeat Ribonuc_2-5A PF06479.7 KLO12505.1 - 1.3e-44 151.1 0.1 2.2e-44 150.4 0.1 1.3 1 0 0 1 1 1 1 Ribonuclease 2-5A Pkinase PF00069.20 KLO12505.1 - 7.7e-43 146.5 0.0 1.2e-42 145.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KLO12505.1 - 1.4e-23 83.2 0.0 5.7e-23 81.3 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase PQQ PF01011.16 KLO12505.1 - 0.0028 17.1 0.0 0.021 14.3 0.0 2.4 2 0 0 2 2 2 1 PQQ enzyme repeat Kdo PF06293.9 KLO12505.1 - 0.044 12.8 0.0 0.1 11.6 0.0 1.6 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family adh_short_C2 PF13561.1 KLO12506.1 - 4.2e-28 98.7 1.1 5.5e-28 98.3 0.8 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 KLO12506.1 - 3.9e-18 65.9 2.4 5.4e-18 65.4 1.7 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KLO12506.1 - 0.0002 21.0 0.2 0.00031 20.4 0.2 1.3 1 0 0 1 1 1 1 KR domain 3HCDH_N PF02737.13 KLO12506.1 - 0.02 14.5 0.1 0.044 13.4 0.1 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Aldedh PF00171.17 KLO12507.1 - 9.3e-123 409.9 0.0 1.1e-122 409.7 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family WD40 PF00400.27 KLO12508.1 - 8.8e-62 202.9 19.6 3.6e-11 42.5 0.1 7.5 7 0 0 7 7 7 7 WD domain, G-beta repeat F-box-like PF12937.2 KLO12508.1 - 1.1e-10 41.0 0.5 2.2e-10 40.0 0.4 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KLO12508.1 - 2.6e-07 30.1 0.2 4.8e-07 29.2 0.2 1.5 1 0 0 1 1 1 1 F-box domain Nup160 PF11715.3 KLO12508.1 - 4e-06 25.2 6.1 1 7.4 0.0 4.4 3 1 2 5 5 5 4 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 KLO12508.1 - 8.8e-05 21.4 1.2 0.26 9.9 0.1 3.9 2 2 2 4 4 4 1 Nup133 N terminal like PQQ_2 PF13360.1 KLO12508.1 - 0.00013 21.4 0.0 0.0024 17.3 0.0 2.5 2 1 1 3 3 3 1 PQQ-like domain BBS2_Mid PF14783.1 KLO12508.1 - 0.0017 18.1 0.0 5.3 6.8 0.0 4.1 3 1 1 4 4 4 1 Ciliary BBSome complex subunit 2, middle region IncA PF04156.9 KLO12509.1 - 0.073 12.6 1.0 0.15 11.6 0.7 1.5 1 0 0 1 1 1 0 IncA protein WD40 PF00400.27 KLO12510.1 - 1.3e-26 91.4 29.9 1.3e-06 27.9 0.1 6.9 8 0 0 8 8 8 6 WD domain, G-beta repeat Nha1_C PF08619.5 KLO12510.1 - 0.032 13.5 8.0 0.059 12.6 5.6 1.3 1 0 0 1 1 1 0 Alkali metal cation/H+ antiporter Nha1 C terminus UPF0139 PF03669.8 KLO12511.1 - 0.0021 17.5 0.0 0.0027 17.1 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0139) F-box-like PF12937.2 KLO12512.1 - 5.7e-08 32.3 5.1 9.3e-07 28.4 3.5 2.4 1 1 0 1 1 1 1 F-box-like F-box PF00646.28 KLO12512.1 - 0.3 10.8 6.5 0.4 10.4 0.2 2.8 3 0 0 3 3 3 0 F-box domain ABC_tran PF00005.22 KLO12514.1 - 1.1e-21 77.6 0.0 2e-21 76.7 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 KLO12514.1 - 2.6e-08 34.2 0.0 5.5e-06 26.5 0.0 2.5 1 1 0 1 1 1 1 AAA domain SMC_N PF02463.14 KLO12514.1 - 1.5e-05 24.3 3.0 0.046 12.9 0.1 2.7 3 0 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 KLO12514.1 - 0.0018 17.7 0.1 0.0058 16.1 0.0 1.8 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_23 PF13476.1 KLO12514.1 - 0.0059 16.9 0.1 0.015 15.6 0.1 1.6 1 0 0 1 1 1 1 AAA domain DUF258 PF03193.11 KLO12514.1 - 0.012 14.7 0.0 0.025 13.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_16 PF13191.1 KLO12514.1 - 0.013 15.5 0.0 0.028 14.4 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.1 KLO12514.1 - 0.051 13.7 0.0 0.27 11.3 0.0 2.1 2 0 0 2 2 2 0 AAA domain G-alpha PF00503.15 KLO12514.1 - 0.054 12.1 0.0 0.099 11.3 0.0 1.3 1 0 0 1 1 1 0 G-protein alpha subunit Zeta_toxin PF06414.7 KLO12514.1 - 0.089 11.8 0.0 0.16 11.0 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin SbcCD_C PF13558.1 KLO12514.1 - 0.11 12.4 0.2 0.35 10.8 0.0 2.0 2 0 0 2 2 2 0 Putative exonuclease SbcCD, C subunit FtsK_SpoIIIE PF01580.13 KLO12514.1 - 0.11 11.9 0.1 0.23 10.8 0.1 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_30 PF13604.1 KLO12514.1 - 0.15 11.6 0.0 0.36 10.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_15 PF13175.1 KLO12514.1 - 0.22 10.5 0.0 0.38 9.7 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain F-box-like PF12937.2 KLO12515.1 - 0.0034 17.0 2.0 0.019 14.6 1.4 2.3 1 1 0 1 1 1 1 F-box-like 4HBT PF03061.17 KLO12516.1 - 2.8e-10 40.1 0.0 6.5e-10 39.0 0.0 1.6 2 0 0 2 2 2 1 Thioesterase superfamily MFS_1 PF07690.11 KLO12517.1 - 1.1e-24 86.8 30.1 1.1e-24 86.8 20.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily ETF_QO PF05187.8 KLO12518.1 - 2.8e-30 104.5 0.0 4.5e-30 103.8 0.0 1.4 1 0 0 1 1 1 1 Electron transfer flavoprotein-ubiquinone oxidoreductase NAD_binding_8 PF13450.1 KLO12518.1 - 1e-07 31.8 0.0 3.5e-07 30.1 0.0 1.9 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 KLO12518.1 - 3.2e-07 29.5 0.0 1.9e-05 23.7 0.0 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 KLO12518.1 - 4e-05 23.5 0.1 8e-05 22.6 0.0 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 KLO12518.1 - 5.2e-05 23.0 0.0 0.00011 21.9 0.0 1.6 1 0 0 1 1 1 1 FAD-NAD(P)-binding FAD_binding_3 PF01494.14 KLO12518.1 - 0.00012 21.2 0.2 0.00019 20.5 0.2 1.3 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.12 KLO12518.1 - 0.00014 21.0 0.1 0.00033 19.8 0.1 1.5 2 0 0 2 2 2 1 Thi4 family HI0933_like PF03486.9 KLO12518.1 - 0.00021 19.9 0.5 0.00021 19.9 0.3 1.6 2 0 0 2 2 2 1 HI0933-like protein FAD_binding_2 PF00890.19 KLO12518.1 - 0.00024 20.1 2.1 0.00028 19.8 0.9 1.5 2 0 0 2 2 2 1 FAD binding domain FAD_oxidored PF12831.2 KLO12518.1 - 0.00024 20.3 0.0 0.00044 19.4 0.0 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 KLO12518.1 - 0.00058 19.9 0.0 0.0012 18.9 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Fer4_7 PF12838.2 KLO12518.1 - 0.0031 17.8 0.3 0.012 16.0 0.3 1.9 2 0 0 2 2 2 1 4Fe-4S dicluster domain Lycopene_cycl PF05834.7 KLO12518.1 - 0.0035 16.3 0.2 0.0052 15.7 0.1 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Trp_halogenase PF04820.9 KLO12518.1 - 0.0042 15.7 0.2 0.0092 14.6 0.1 1.6 1 0 0 1 1 1 1 Tryptophan halogenase Pyr_redox PF00070.22 KLO12518.1 - 0.038 14.4 0.2 1.1 9.7 0.2 2.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 KLO12518.1 - 0.073 11.9 0.3 0.16 10.7 0.1 1.6 2 0 0 2 2 2 0 Glucose inhibited division protein A Fer4_9 PF13187.1 KLO12518.1 - 0.09 13.0 0.7 0.21 11.8 0.5 1.6 1 0 0 1 1 1 0 4Fe-4S dicluster domain K_oxygenase PF13434.1 KLO12518.1 - 0.17 10.7 0.0 0.29 10.0 0.0 1.3 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) Fer4_2 PF12797.2 KLO12518.1 - 1.8 8.6 4.7 0.28 11.2 0.4 1.9 2 0 0 2 2 1 0 4Fe-4S binding domain Fer4_6 PF12837.2 KLO12518.1 - 2.1 8.3 4.2 1.5 8.8 0.7 2.2 2 0 0 2 2 2 0 4Fe-4S binding domain Fer2 PF00111.22 KLO12519.1 - 1.1e-10 41.1 0.0 1.5e-10 40.7 0.0 1.2 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain FlgD_ig PF13860.1 KLO12519.1 - 0.045 13.4 0.0 0.064 13.0 0.0 1.3 1 0 0 1 1 1 0 FlgD Ig-like domain Adap_comp_sub PF00928.16 KLO12520.1 - 2.9e-91 305.2 0.0 4.1e-91 304.7 0.0 1.2 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.15 KLO12520.1 - 3.6e-06 26.7 0.2 6.4e-06 25.9 0.1 1.4 1 0 0 1 1 1 1 Clathrin adaptor complex small chain DUF3943 PF13084.1 KLO12520.1 - 0.14 11.7 0.0 0.26 10.8 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3943) Formyl_trans_N PF00551.14 KLO12521.1 - 6.6e-35 120.2 0.0 6.2e-17 61.7 0.0 2.0 2 0 0 2 2 2 2 Formyl transferase Spo7 PF03907.8 KLO12523.1 - 9e-19 67.9 2.4 2.1e-17 63.4 0.0 2.3 2 1 0 2 2 2 2 Spo7-like protein PHP PF02811.14 KLO12524.1 - 1.8e-10 40.9 0.0 2.3e-10 40.5 0.0 1.3 1 0 0 1 1 1 1 PHP domain Rnk_N PF14760.1 KLO12524.1 - 0.033 14.2 1.0 0.097 12.7 0.2 2.2 2 0 0 2 2 2 0 Rnk N-terminus DUF1688 PF07958.6 KLO12526.1 - 2.4e-158 527.0 0.0 2.7e-158 526.8 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1688) MFS_2 PF13347.1 KLO12527.1 - 6.8e-14 51.0 10.5 6.8e-14 51.0 7.3 1.8 3 0 0 3 3 3 1 MFS/sugar transport protein MFS_1_like PF12832.2 KLO12527.1 - 0.0071 16.1 0.0 0.0071 16.1 0.0 3.1 3 1 0 3 3 3 1 MFS_1 like family PQ-loop PF04193.9 KLO12529.1 - 6.8e-19 67.1 12.8 5.4e-10 38.6 0.4 3.4 2 1 1 3 3 3 2 PQ loop repeat DUF3989 PF13150.1 KLO12530.1 - 0.16 11.3 1.0 0.21 11.0 0.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3989) His_Phos_2 PF00328.17 KLO12534.1 - 7.9e-43 147.1 0.0 9.7e-43 146.8 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Fascin PF06268.8 KLO12535.1 - 0.018 15.1 0.1 0.12 12.5 0.0 2.0 2 0 0 2 2 2 0 Fascin domain CFEM PF05730.6 KLO12540.1 - 1.5e-07 31.1 16.4 2.2e-07 30.6 11.3 1.2 1 0 0 1 1 1 1 CFEM domain TIL PF01826.12 KLO12540.1 - 4.8 7.3 14.5 9.2 6.4 10.0 1.4 1 0 0 1 1 1 0 Trypsin Inhibitor like cysteine rich domain Glyco_hydro_61 PF03443.9 KLO12541.1 - 1.2e-62 211.6 0.2 1.3e-62 211.4 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Tir_receptor_C PF07489.6 KLO12543.1 - 0.28 10.8 6.5 0.46 10.2 4.5 1.3 1 0 0 1 1 1 0 Translocated intimin receptor (Tir) C-terminus F-box-like PF12937.2 KLO12544.1 - 9.3e-08 31.6 0.1 2.4e-07 30.3 0.1 1.8 1 0 0 1 1 1 1 F-box-like DUF1090 PF06476.7 KLO12545.1 - 0.07 12.7 0.0 0.11 12.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1090) DUF1426 PF07234.6 KLO12545.1 - 0.072 12.8 1.1 0.16 11.7 0.4 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1426) PSRT PF07636.6 KLO12545.1 - 3.7 7.1 6.9 9.8 5.7 4.8 1.6 1 0 0 1 1 1 0 PSRT zf-MYND PF01753.13 KLO12546.1 - 1.9e-10 40.3 17.2 1.9e-10 40.3 11.9 2.4 2 0 0 2 2 2 1 MYND finger zf-MYND PF01753.13 KLO12547.1 - 6.2e-09 35.5 13.2 6.2e-09 35.5 9.2 2.3 2 0 0 2 2 2 1 MYND finger F-box-like PF12937.2 KLO12548.1 - 5.1e-05 22.8 0.1 0.0001 21.9 0.1 1.5 1 0 0 1 1 1 1 F-box-like zf-MYND PF01753.13 KLO12549.1 - 1.8e-08 34.0 16.0 1.8e-08 34.0 11.1 2.4 3 0 0 3 3 3 1 MYND finger zf-Mss51 PF13824.1 KLO12549.1 - 0.082 12.7 5.6 0.21 11.4 3.9 1.7 1 0 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 zf-MYND PF01753.13 KLO12550.1 - 1.2e-10 41.1 12.0 1.7e-10 40.5 8.3 1.3 1 0 0 1 1 1 1 MYND finger Ecl1 PF12855.2 KLO12550.1 - 0.0063 15.7 3.5 0.011 14.9 2.4 1.6 1 0 0 1 1 1 1 Life-span regulatory factor GH-E PF14410.1 KLO12550.1 - 0.036 14.1 0.4 0.046 13.8 0.3 1.2 1 1 0 1 1 1 0 HNH/ENDO VII superfamily nuclease with conserved GHE residues DUF581 PF04570.9 KLO12550.1 - 0.68 9.2 7.1 2.1 7.7 0.4 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF581) zf-Mss51 PF13824.1 KLO12550.1 - 3.5 7.5 7.7 6.4 6.7 5.3 1.6 1 1 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 zf-MYND PF01753.13 KLO12551.1 - 1.3e-10 40.9 11.8 1.3e-10 40.9 8.2 2.7 3 0 0 3 3 3 1 MYND finger F-box-like PF12937.2 KLO12553.1 - 1.7e-05 24.4 0.0 3.3e-05 23.5 0.0 1.5 1 0 0 1 1 1 1 F-box-like F-box-like PF12937.2 KLO12554.1 - 6e-09 35.5 1.3 1.3e-08 34.3 0.1 2.3 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 KLO12554.1 - 3.4e-07 29.7 0.7 1e-06 28.2 0.1 2.1 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.2 KLO12556.1 - 1.3e-08 34.3 0.5 3.9e-08 32.8 0.1 2.0 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 KLO12556.1 - 8.1e-05 22.1 0.1 0.00023 20.7 0.0 1.7 1 0 0 1 1 1 1 F-box domain Cerato-platanin PF07249.7 KLO12557.1 - 7.7e-42 142.0 0.4 8.9e-42 141.8 0.3 1.0 1 0 0 1 1 1 1 Cerato-platanin AdoHcyase_NAD PF00670.16 KLO12557.1 - 0.023 14.5 0.0 0.033 14.0 0.0 1.1 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain DUF3060 PF11259.3 KLO12557.1 - 0.13 11.8 0.8 8 6.1 0.1 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF3060) DRIM PF07539.7 KLO12558.1 - 1.1e-27 96.1 0.0 5.1e-27 94.0 0.0 2.3 1 0 0 1 1 1 1 Down-regulated in metastasis MMS19_N PF14500.1 KLO12558.1 - 2.1e-05 23.9 9.8 0.1 11.8 0.1 5.2 5 1 1 6 6 6 3 Dos2-interacting transcription regulator of RNA-Pol-II HEAT PF02985.17 KLO12558.1 - 0.00011 22.0 7.4 9.9 6.5 0.0 7.5 9 0 0 9 9 9 2 HEAT repeat HEAT_EZ PF13513.1 KLO12558.1 - 0.036 14.5 1.4 3.2 8.3 0.0 5.3 4 0 0 4 4 4 0 HEAT-like repeat Xpo1 PF08389.7 KLO12558.1 - 0.12 12.3 8.7 23 4.8 0.3 6.2 5 2 0 5 5 5 0 Exportin 1-like protein Ceramidase_alk PF04734.8 KLO12559.1 - 1.1e-242 806.7 0.0 1.2e-242 806.6 0.0 1.0 1 0 0 1 1 1 1 Neutral/alkaline non-lysosomal ceramidase Cellulase PF00150.13 KLO12560.1 - 3.7e-07 29.6 0.0 6.6e-07 28.8 0.0 1.4 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) PBP1_TM PF14812.1 KLO12560.1 - 0.0098 16.1 0.0 0.016 15.4 0.0 1.2 1 0 0 1 1 1 1 Transmembrane domain of transglycosylase PBP1 at N-terminal GRA6 PF05084.8 KLO12560.1 - 0.019 14.5 3.2 0.036 13.5 2.2 1.4 1 0 0 1 1 1 0 Granule antigen protein (GRA6) TEA PF01285.13 KLO12563.1 - 6.2e-13 48.7 0.0 6.2e-13 48.7 0.0 2.6 3 0 0 3 3 3 1 TEA/ATTS domain family Pinin_SDK_memA PF04696.8 KLO12565.1 - 7.4e-11 41.7 9.4 7.4e-11 41.7 6.5 2.9 2 1 2 4 4 4 2 pinin/SDK/memA/ protein conserved region Drf_GBD PF06371.8 KLO12565.1 - 0.081 12.2 1.9 0.15 11.4 1.3 1.3 1 0 0 1 1 1 0 Diaphanous GTPase-binding Domain HSP70 PF00012.15 KLO12567.1 - 0.001 17.0 0.0 0.0016 16.4 0.0 1.2 1 0 0 1 1 1 1 Hsp70 protein FGGY_C PF02782.11 KLO12567.1 - 0.013 15.1 0.0 0.035 13.7 0.0 1.7 2 0 0 2 2 2 0 FGGY family of carbohydrate kinases, C-terminal domain IncA PF04156.9 KLO12568.1 - 0.0024 17.4 2.5 0.0024 17.4 1.7 2.4 2 0 0 2 2 2 1 IncA protein TMPIT PF07851.8 KLO12568.1 - 0.6 9.1 5.2 1.3 8.0 3.6 1.6 1 0 0 1 1 1 0 TMPIT-like protein Erp_C PF06780.6 KLO12568.1 - 1.3 8.8 8.1 0.54 10.0 2.7 2.2 2 0 0 2 2 2 0 Erp protein C-terminus DUF3554 PF12074.3 KLO12569.1 - 9.6e-47 160.0 11.1 9.5e-46 156.7 0.9 5.3 6 1 1 7 7 7 1 Domain of unknown function (DUF3554) HEAT_2 PF13646.1 KLO12569.1 - 7.9e-39 131.8 35.2 4.8e-08 33.1 0.0 14.9 8 4 6 15 15 15 9 HEAT repeats HEAT_EZ PF13513.1 KLO12569.1 - 6.4e-36 121.9 26.9 0.0002 21.7 0.1 17.5 13 4 5 18 18 17 9 HEAT-like repeat HEAT PF02985.17 KLO12569.1 - 1.1e-33 112.2 22.5 0.066 13.3 0.0 20.8 21 0 0 21 21 21 8 HEAT repeat CLASP_N PF12348.3 KLO12569.1 - 3.9e-15 55.8 0.4 1.2e-05 24.8 0.0 8.8 8 2 1 10 10 10 3 CLASP N terminal Vac14_Fab1_bd PF12755.2 KLO12569.1 - 1.8e-08 34.6 0.0 0.49 10.8 0.0 7.2 7 1 1 8 8 8 1 Vacuolar 14 Fab1-binding region Cnd1 PF12717.2 KLO12569.1 - 2.9e-07 30.5 0.2 4 7.2 0.0 8.6 9 1 2 11 11 11 1 non-SMC mitotic condensation complex subunit 1 DUF3535 PF12054.3 KLO12569.1 - 4.8e-05 22.1 0.3 0.022 13.4 0.0 3.8 3 1 1 4 4 4 1 Domain of unknown function (DUF3535) Cohesin_HEAT PF12765.2 KLO12569.1 - 0.04 13.8 6.4 6.5 6.8 0.1 5.0 4 0 0 4 4 4 0 HEAT repeat associated with sister chromatid cohesion DUF2669 PF10876.3 KLO12569.1 - 0.048 13.3 0.0 5 6.8 0.0 3.2 2 1 0 2 2 2 0 Protein of unknown function (DUF2669) HEAT_PBS PF03130.11 KLO12569.1 - 0.26 11.8 11.2 8.9 7.0 0.2 7.7 9 0 0 9 9 9 0 PBS lyase HEAT-like repeat S10_plectin PF03501.10 KLO12571.1 - 6.8e-39 131.6 0.1 8e-39 131.4 0.0 1.1 1 0 0 1 1 1 1 Plectin/S10 domain NAD_binding_5 PF07994.7 KLO12575.1 - 2.3e-104 349.0 0.0 2.8e-104 348.7 0.0 1.0 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase Inos-1-P_synth PF01658.12 KLO12575.1 - 8.4e-44 147.9 0.0 1.6e-43 147.0 0.0 1.5 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase Phage_B PF02304.10 KLO12577.1 - 0.00014 22.0 0.1 0.0015 18.8 0.0 2.4 2 0 0 2 2 2 1 Scaffold protein B Helitron_like_N PF14214.1 KLO12577.1 - 0.00021 21.0 0.0 0.00047 19.9 0.0 1.6 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus PIF1 PF05970.9 KLO12579.1 - 0.014 14.3 0.0 0.016 14.1 0.0 1.1 1 0 0 1 1 1 0 PIF1-like helicase NRPS PF08415.5 KLO12579.1 - 0.16 11.7 0.1 0.3 10.8 0.1 1.6 1 1 0 1 1 1 0 Nonribosomal peptide synthase Herpes_Helicase PF02689.9 KLO12580.1 - 0.0018 16.1 0.0 0.0018 16.1 0.0 1.0 1 0 0 1 1 1 1 Helicase DUF4176 PF13780.1 KLO12582.1 - 0.031 13.9 0.0 0.084 12.6 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4176) GrpE PF01025.14 KLO12584.1 - 8.3e-42 142.5 0.8 3e-41 140.7 0.6 1.7 1 1 0 1 1 1 1 GrpE Formyl_trans_N PF00551.14 KLO12584.1 - 0.048 13.2 0.0 0.071 12.6 0.0 1.3 1 0 0 1 1 1 0 Formyl transferase DNA_repr_REX1B PF14966.1 KLO12585.1 - 0.033 14.5 3.2 0.14 12.5 0.9 2.6 1 1 1 2 2 2 0 DNA repair REX1-B TMEM171 PF15471.1 KLO12585.1 - 0.12 11.1 0.7 0.2 10.4 0.5 1.3 1 0 0 1 1 1 0 Transmembrane protein family 171 ALMT PF11744.3 KLO12585.1 - 0.14 10.7 2.5 0.25 9.9 1.7 1.4 1 0 0 1 1 1 0 Aluminium activated malate transporter GNT-I PF03071.10 KLO12585.1 - 0.41 9.1 3.7 1.1 7.7 0.4 2.3 2 0 0 2 2 2 0 GNT-I family Reo_sigmaC PF04582.7 KLO12585.1 - 0.68 9.0 4.4 1.2 8.2 0.8 2.6 2 0 0 2 2 2 0 Reovirus sigma C capsid protein IncA PF04156.9 KLO12585.1 - 1.4 8.5 26.9 0.14 11.7 11.2 3.1 2 2 0 2 2 2 0 IncA protein Syntaxin PF00804.20 KLO12585.1 - 1.4 9.0 20.1 0.49 10.5 2.0 3.8 3 1 1 4 4 4 0 Syntaxin AAA_13 PF13166.1 KLO12585.1 - 1.5 7.1 16.1 0.12 10.8 6.2 2.1 2 0 0 2 2 2 0 AAA domain THP2 PF09432.5 KLO12585.1 - 1.6 8.6 9.5 0.38 10.6 1.4 3.0 2 1 1 3 3 3 0 Tho complex subunit THP2 Atg14 PF10186.4 KLO12585.1 - 2.5 6.9 26.1 0.015 14.2 7.6 3.5 3 1 0 3 3 3 0 UV radiation resistance protein and autophagy-related subunit 14 ATG16 PF08614.6 KLO12585.1 - 2.8 7.7 28.1 0.14 11.9 8.7 3.3 2 1 1 3 3 3 0 Autophagy protein 16 (ATG16) KxDL PF10241.4 KLO12585.1 - 4.7 7.1 7.2 4.7 7.1 0.5 3.1 1 1 0 2 2 2 0 Uncharacterized conserved protein DUF3552 PF12072.3 KLO12586.1 - 0.00033 19.9 1.6 0.0018 17.5 0.5 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF3552) SMC_N PF02463.14 KLO12587.1 - 3.2e-28 98.4 0.0 5.4e-28 97.7 0.0 1.3 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 KLO12587.1 - 1.5e-19 71.1 1.8 1.5e-19 71.1 1.3 4.8 3 2 1 4 4 4 1 AAA domain AAA_21 PF13304.1 KLO12587.1 - 2e-05 24.7 3.1 0.0017 18.4 0.1 3.4 3 1 0 3 3 3 2 AAA domain AAA_15 PF13175.1 KLO12587.1 - 2.7e-05 23.4 10.7 2.7e-05 23.4 7.4 2.8 2 1 0 2 2 2 1 AAA ATPase domain AAA_29 PF13555.1 KLO12587.1 - 0.00013 21.3 0.2 0.00044 19.7 0.0 1.9 2 0 0 2 2 2 1 P-loop containing region of AAA domain SMC_hinge PF06470.8 KLO12587.1 - 0.00077 19.4 0.5 0.0044 16.9 0.0 2.5 3 0 0 3 3 3 1 SMC proteins Flexible Hinge Domain SbcCD_C PF13558.1 KLO12587.1 - 0.011 15.6 0.1 0.037 13.9 0.0 2.0 2 0 0 2 2 2 0 Putative exonuclease SbcCD, C subunit PAS_10 PF13596.1 KLO12587.1 - 0.19 11.9 4.2 1.1 9.5 0.3 3.7 3 0 0 3 3 3 0 PAS domain DUF2418 PF10332.4 KLO12588.1 - 7.3e-25 87.1 0.3 7.3e-25 87.1 0.2 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF2418) FAD_binding_3 PF01494.14 KLO12589.1 - 6.2e-25 88.0 2.6 1.9e-23 83.1 1.8 2.6 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 KLO12589.1 - 2.1e-05 24.4 2.9 4.7e-05 23.3 1.1 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 KLO12589.1 - 0.00045 20.5 1.8 0.00096 19.5 1.3 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 KLO12589.1 - 0.00093 17.9 0.6 0.0016 17.1 0.4 1.3 1 0 0 1 1 1 1 Tryptophan halogenase Amino_oxidase PF01593.19 KLO12589.1 - 0.0013 17.9 1.7 0.12 11.3 0.0 2.9 3 0 0 3 3 3 1 Flavin containing amine oxidoreductase HI0933_like PF03486.9 KLO12589.1 - 0.0017 16.9 3.0 0.0017 16.9 2.1 1.4 2 0 0 2 2 2 1 HI0933-like protein Thi4 PF01946.12 KLO12589.1 - 0.0055 15.8 0.6 0.0095 15.0 0.4 1.3 1 0 0 1 1 1 1 Thi4 family Syndecan PF01034.15 KLO12589.1 - 0.0073 15.9 0.1 0.015 14.9 0.0 1.5 1 0 0 1 1 1 1 Syndecan domain DAO PF01266.19 KLO12589.1 - 0.011 14.6 5.2 0.023 13.5 3.6 1.5 1 0 0 1 1 1 0 FAD dependent oxidoreductase GIDA PF01134.17 KLO12589.1 - 0.016 14.1 1.5 0.022 13.6 1.0 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A Pyr_redox_2 PF07992.9 KLO12589.1 - 0.053 13.4 2.3 0.098 12.5 1.6 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.16 KLO12589.1 - 0.056 12.9 2.0 0.21 11.1 0.8 2.3 2 1 1 3 3 3 0 Alanine dehydrogenase/PNT, C-terminal domain SE PF08491.5 KLO12589.1 - 0.059 12.1 0.0 0.094 11.5 0.0 1.2 1 0 0 1 1 1 0 Squalene epoxidase UDPG_MGDP_dh_N PF03721.9 KLO12589.1 - 0.13 11.6 1.0 0.21 10.9 0.7 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NAD_binding_9 PF13454.1 KLO12589.1 - 0.15 11.7 3.1 0.82 9.4 0.3 2.9 2 1 1 3 3 3 0 FAD-NAD(P)-binding FAD_binding_2 PF00890.19 KLO12589.1 - 0.19 10.5 2.9 0.29 9.9 2.0 1.3 1 0 0 1 1 1 0 FAD binding domain 3HCDH_N PF02737.13 KLO12589.1 - 0.25 11.0 2.7 0.49 10.0 1.8 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pyr_redox_3 PF13738.1 KLO12589.1 - 0.39 10.7 2.9 0.54 10.2 0.8 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 KLO12590.1 - 5.6e-20 71.7 6.1 1e-17 64.2 4.2 2.9 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 KLO12590.1 - 5.7e-06 26.2 2.4 1.5e-05 24.9 1.7 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 KLO12590.1 - 0.00023 20.2 4.7 0.00045 19.2 3.3 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.9 KLO12590.1 - 0.0004 18.9 2.6 0.00074 18.0 1.8 1.4 1 0 0 1 1 1 1 HI0933-like protein Amino_oxidase PF01593.19 KLO12590.1 - 0.0011 18.1 0.0 0.12 11.4 0.0 2.2 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase Pyr_redox PF00070.22 KLO12590.1 - 0.0012 19.1 5.5 0.0024 18.2 1.9 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 KLO12590.1 - 0.0046 15.6 0.4 0.0046 15.6 0.3 1.4 2 0 0 2 2 2 1 Tryptophan halogenase FAD_binding_2 PF00890.19 KLO12590.1 - 0.0072 15.2 3.5 0.011 14.6 2.4 1.2 1 0 0 1 1 1 1 FAD binding domain GIDA PF01134.17 KLO12590.1 - 0.012 14.5 2.5 0.017 14.0 1.8 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A Thi4 PF01946.12 KLO12590.1 - 0.012 14.7 0.4 0.012 14.7 0.3 1.6 2 0 0 2 2 2 0 Thi4 family Pyr_redox_2 PF07992.9 KLO12590.1 - 0.028 14.3 1.3 0.055 13.3 0.9 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase SE PF08491.5 KLO12590.1 - 0.071 11.9 0.0 0.11 11.3 0.0 1.2 1 0 0 1 1 1 0 Squalene epoxidase NAD_binding_9 PF13454.1 KLO12590.1 - 0.095 12.4 1.6 1.9 8.2 0.4 3.0 2 1 1 3 3 3 0 FAD-NAD(P)-binding 3HCDH_N PF02737.13 KLO12590.1 - 0.15 11.7 1.9 0.28 10.8 1.3 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_oxidored PF12831.2 KLO12590.1 - 0.38 9.7 4.1 0.54 9.2 2.9 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase FBPase PF00316.15 KLO12591.1 - 6.6e-130 432.6 0.0 7.6e-130 432.4 0.0 1.0 1 0 0 1 1 1 1 Fructose-1-6-bisphosphatase Inositol_P PF00459.20 KLO12591.1 - 1.8e-05 24.1 0.0 3e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 Inositol monophosphatase family zf-C2H2 PF00096.21 KLO12592.1 - 4.4e-22 77.0 16.8 7.4e-06 26.0 0.3 4.1 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 KLO12592.1 - 6.4e-22 76.7 16.3 1.9e-07 31.0 0.0 4.9 5 0 0 5 5 5 3 Zinc-finger double domain zf-C2H2_4 PF13894.1 KLO12592.1 - 6.1e-17 60.6 15.6 5e-05 23.3 0.3 4.1 4 0 0 4 4 4 4 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 KLO12592.1 - 1.5e-07 31.3 4.0 0.3 11.2 0.0 4.2 4 0 0 4 4 4 3 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 KLO12592.1 - 3.3e-05 23.6 2.9 0.013 15.4 0.0 4.1 4 0 0 4 4 4 1 C2H2-type zinc finger zf-met PF12874.2 KLO12592.1 - 0.00026 21.0 5.2 1.3 9.3 0.0 4.3 4 0 0 4 4 4 2 Zinc-finger of C2H2 type Ogr_Delta PF04606.7 KLO12592.1 - 0.00026 20.5 2.5 2.5 7.8 0.0 3.3 1 1 2 3 3 3 2 Ogr/Delta-like zinc finger zf-CGNR PF11706.3 KLO12592.1 - 0.00059 19.2 2.7 2.5 7.6 0.1 3.3 3 0 0 3 3 3 2 CGNR zinc finger zf-TRAF PF02176.13 KLO12592.1 - 0.0011 19.2 5.1 0.016 15.5 1.2 2.6 2 1 1 3 3 3 1 TRAF-type zinc finger Viral_helicase1 PF01443.13 KLO12592.1 - 0.024 14.1 2.2 3.1 7.2 0.2 2.4 2 1 0 2 2 2 0 Viral (Superfamily 1) RNA helicase CHORD PF04968.7 KLO12592.1 - 0.038 14.2 5.8 14 5.9 0.0 3.3 2 1 1 3 3 3 0 CHORD zf-C2HC_2 PF13913.1 KLO12592.1 - 0.11 12.2 1.5 8.5 6.1 0.0 3.5 4 0 0 4 4 4 0 zinc-finger of a C2HC-type Pmp3 PF01679.12 KLO12593.1 - 5.5e-15 54.8 6.8 7e-15 54.4 4.7 1.1 1 0 0 1 1 1 1 Proteolipid membrane potential modulator SF3b1 PF08920.5 KLO12593.1 - 2 8.4 9.9 0.3 11.1 2.2 2.3 2 0 0 2 2 2 0 Splicing factor 3B subunit 1 PNGaseA PF12222.3 KLO12594.1 - 2.1e-83 280.6 5.5 2.9e-83 280.1 3.8 1.1 1 0 0 1 1 1 1 Peptide N-acetyl-beta-D-glucosaminyl asparaginase amidase A FTHFS PF01268.14 KLO12595.1 - 7.1e-261 866.0 0.0 1e-260 865.5 0.0 1.2 1 0 0 1 1 1 1 Formate--tetrahydrofolate ligase THF_DHG_CYH_C PF02882.14 KLO12595.1 - 5.2e-67 223.9 0.7 1.5e-66 222.4 0.1 2.2 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain THF_DHG_CYH PF00763.18 KLO12595.1 - 3.1e-34 117.4 0.2 9.9e-34 115.8 0.1 1.9 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain IF2_N PF04760.10 KLO12595.1 - 0.082 12.5 0.0 6.6 6.4 0.0 2.7 2 0 0 2 2 2 0 Translation initiation factor IF-2, N-terminal region Coa1 PF08695.5 KLO12596.1 - 6.8e-35 119.0 0.0 8e-35 118.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome oxidase complex assembly protein 1 Aldo_ket_red PF00248.16 KLO12597.1 - 1.7e-52 178.0 0.0 1.9e-52 177.8 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family CDP-OH_P_transf PF01066.16 KLO12598.1 - 4.1e-19 68.7 3.8 4.1e-19 68.7 2.6 2.1 2 0 0 2 2 2 1 CDP-alcohol phosphatidyltransferase Herpes_U15 PF05613.6 KLO12598.1 - 0.14 12.4 1.1 0.28 11.5 0.8 1.5 1 0 0 1 1 1 0 Human herpesvirus U15 protein Pex24p PF06398.6 KLO12598.1 - 1.3 7.7 5.7 4 6.1 0.0 2.3 2 1 0 2 2 2 0 Integral peroxisomal membrane peroxin AAA PF00004.24 KLO12599.1 - 1.7e-35 122.0 0.0 3.8e-35 120.9 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 KLO12599.1 - 4.6e-06 26.7 0.5 0.0009 19.2 0.0 3.2 3 1 1 4 4 3 1 AAA ATPase domain AAA_5 PF07728.9 KLO12599.1 - 8.6e-05 22.2 0.2 0.00057 19.6 0.0 2.5 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_17 PF13207.1 KLO12599.1 - 0.00017 22.3 0.5 0.0019 19.0 0.1 3.0 2 1 0 2 2 2 1 AAA domain AAA_22 PF13401.1 KLO12599.1 - 0.00046 20.3 0.0 0.018 15.1 0.0 2.6 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 KLO12599.1 - 0.0005 19.7 0.7 0.0023 17.6 0.1 2.3 2 0 0 2 2 2 1 Part of AAA domain AAA_11 PF13086.1 KLO12599.1 - 0.0043 16.6 0.0 0.009 15.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.1 KLO12599.1 - 0.0068 16.3 0.0 0.019 14.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 KLO12599.1 - 0.015 15.1 0.0 0.037 13.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.12 KLO12599.1 - 0.025 14.0 0.0 0.056 12.8 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_18 PF13238.1 KLO12599.1 - 0.028 14.7 0.0 0.096 12.9 0.0 1.9 1 0 0 1 1 1 0 AAA domain RuvB_N PF05496.7 KLO12599.1 - 0.034 13.1 0.0 0.063 12.3 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus AAA_25 PF13481.1 KLO12599.1 - 0.052 12.9 1.2 2.7 7.3 0.1 3.0 2 1 1 3 3 3 0 AAA domain AAA_14 PF13173.1 KLO12599.1 - 0.053 13.4 0.0 0.13 12.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_10 PF12846.2 KLO12599.1 - 0.066 12.6 0.0 4 6.7 0.0 2.6 1 1 1 2 2 2 0 AAA-like domain DUF815 PF05673.8 KLO12599.1 - 0.079 11.8 0.0 0.14 11.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Mg_chelatase PF01078.16 KLO12599.1 - 0.17 11.0 0.3 0.64 9.1 0.2 1.9 1 1 0 1 1 1 0 Magnesium chelatase, subunit ChlI TIP49 PF06068.8 KLO12599.1 - 0.22 10.1 0.0 0.35 9.5 0.0 1.2 1 0 0 1 1 1 0 TIP49 C-terminus Rad17 PF03215.10 KLO12599.1 - 0.22 10.1 0.0 0.37 9.4 0.0 1.2 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein SMC_Nse1 PF07574.8 KLO12600.1 - 9.5e-27 93.9 0.0 1.2e-25 90.3 0.0 2.1 1 1 0 1 1 1 1 Nse1 non-SMC component of SMC5-6 complex zf-RING-like PF08746.6 KLO12600.1 - 1.2e-06 28.3 10.3 2.2e-06 27.5 7.2 1.4 1 0 0 1 1 1 1 RING-like domain zf-RING_2 PF13639.1 KLO12600.1 - 6.7e-05 22.6 10.0 0.00011 21.9 6.9 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 KLO12600.1 - 0.002 18.0 10.4 0.0036 17.2 7.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-HC5HC2H_2 PF13832.1 KLO12600.1 - 0.011 15.7 4.7 0.021 14.7 3.2 1.5 1 0 0 1 1 1 0 PHD-zinc-finger like domain zf-HC5HC2H PF13771.1 KLO12600.1 - 0.27 11.4 8.8 0.36 11.0 5.5 1.6 1 1 0 1 1 1 0 PHD-like zinc-binding domain zf-RING_5 PF14634.1 KLO12600.1 - 0.36 10.6 10.7 0.58 9.9 7.5 1.3 1 0 0 1 1 1 0 zinc-RING finger domain PHD PF00628.24 KLO12600.1 - 0.99 9.1 8.9 1.9 8.2 6.2 1.5 1 0 0 1 1 1 0 PHD-finger CDP-OH_P_transf PF01066.16 KLO12601.1 - 4.5e-12 46.1 2.9 9.6e-12 45.0 2.0 1.5 1 0 0 1 1 1 1 CDP-alcohol phosphatidyltransferase CRCB PF02537.10 KLO12601.1 - 0.032 14.1 0.8 0.075 12.9 0.1 2.0 2 0 0 2 2 2 0 CrcB-like protein DNA_primase_lrg PF04104.9 KLO12602.1 - 2.6e-81 272.7 0.0 3.3e-81 272.3 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic and archaeal DNA primase, large subunit Asn_synthase PF00733.16 KLO12603.1 - 3.9e-71 239.5 0.0 9.8e-71 238.2 0.0 1.6 2 0 0 2 2 2 1 Asparagine synthase GATase_7 PF13537.1 KLO12603.1 - 1.5e-34 118.4 0.0 2.5e-34 117.6 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.1 KLO12603.1 - 2.1e-28 98.9 0.0 5.3e-28 97.6 0.0 1.7 2 0 0 2 2 2 1 Glutamine amidotransferase domain GATase_2 PF00310.16 KLO12603.1 - 3.5e-06 25.9 0.0 0.15 10.7 0.0 3.1 1 1 2 3 3 3 3 Glutamine amidotransferases class-II DUF3700 PF12481.3 KLO12603.1 - 9.5e-05 21.6 0.0 0.00024 20.3 0.0 1.6 2 0 0 2 2 2 1 Aluminium induced protein QueC PF06508.8 KLO12603.1 - 0.032 13.5 0.0 0.056 12.7 0.0 1.3 1 0 0 1 1 1 0 Queuosine biosynthesis protein QueC NAD_synthase PF02540.12 KLO12603.1 - 0.044 12.6 0.0 0.078 11.8 0.0 1.3 1 0 0 1 1 1 0 NAD synthase RhoGEF PF00621.15 KLO12605.1 - 5.6e-19 68.7 0.1 5.3e-14 52.4 0.0 2.3 2 0 0 2 2 2 2 RhoGEF domain Methyltransf_16 PF10294.4 KLO12606.1 - 4.9e-16 58.6 0.0 1e-09 38.0 0.0 2.8 2 1 0 2 2 2 2 Putative methyltransferase Methyltransf_18 PF12847.2 KLO12606.1 - 0.00034 21.1 0.0 0.00089 19.8 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KLO12606.1 - 0.00072 19.3 0.0 0.0012 18.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain SAM_MT PF04445.8 KLO12606.1 - 0.029 13.5 0.0 0.044 12.9 0.0 1.2 1 0 0 1 1 1 0 Putative SAM-dependent methyltransferase Methyltransf_12 PF08242.7 KLO12606.1 - 0.08 13.4 0.0 15 6.1 0.0 2.6 3 0 0 3 3 3 0 Methyltransferase domain EF_assoc_2 PF08356.7 KLO12607.1 - 0.11 12.3 0.0 0.17 11.6 0.0 1.3 1 0 0 1 1 1 0 EF hand associated Hexapep PF00132.19 KLO12608.1 - 5.9e-08 31.8 3.1 0.0012 18.2 0.2 3.5 2 1 1 3 3 3 2 Bacterial transferase hexapeptide (six repeats) W2 PF02020.13 KLO12608.1 - 6.4e-08 32.4 0.1 6.4e-08 32.4 0.1 2.7 3 0 0 3 3 3 1 eIF4-gamma/eIF5/eIF2-epsilon NTP_transf_3 PF12804.2 KLO12608.1 - 0.00083 19.4 0.0 0.0015 18.6 0.0 1.4 1 0 0 1 1 1 1 MobA-like NTP transferase domain Nop14 PF04147.7 KLO12608.1 - 0.19 9.6 14.4 0.31 8.9 10.0 1.2 1 0 0 1 1 1 0 Nop14-like family Daxx PF03344.10 KLO12608.1 - 0.36 9.2 9.3 0.53 8.6 6.4 1.2 1 0 0 1 1 1 0 Daxx Family Hexapep_2 PF14602.1 KLO12608.1 - 1 8.9 10.1 2.3 7.8 1.2 3.6 1 1 1 2 2 2 0 Hexapeptide repeat of succinyl-transferase Pmp3 PF01679.12 KLO12609.1 - 8.8e-16 57.3 2.5 1.6e-15 56.5 1.7 1.4 1 0 0 1 1 1 1 Proteolipid membrane potential modulator DUF1751 PF08551.5 KLO12609.1 - 0.009 16.3 0.1 0.012 15.9 0.0 1.3 1 1 0 1 1 1 1 Eukaryotic integral membrane protein (DUF1751) Aminotran_5 PF00266.14 KLO12610.1 - 1.8e-11 43.3 0.0 2.7e-11 42.8 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V FAD_binding_3 PF01494.14 KLO12611.1 - 9.8e-17 61.0 0.0 4.1e-16 58.9 0.0 1.9 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 KLO12611.1 - 2.2e-06 26.8 0.1 4.4e-06 25.8 0.0 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KLO12611.1 - 3.1e-05 23.9 0.0 8.1e-05 22.5 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.2 KLO12611.1 - 0.00014 21.0 0.4 0.00064 18.9 0.3 1.8 1 1 0 1 1 1 1 FAD dependent oxidoreductase GIDA PF01134.17 KLO12611.1 - 0.00024 20.0 0.1 0.00045 19.1 0.1 1.4 1 1 0 1 1 1 1 Glucose inhibited division protein A Pyr_redox PF00070.22 KLO12611.1 - 0.00037 20.8 0.0 0.0043 17.4 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 KLO12611.1 - 0.00038 20.3 0.0 0.0007 19.5 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.11 KLO12611.1 - 0.0016 17.8 0.0 0.0029 17.0 0.0 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA HI0933_like PF03486.9 KLO12611.1 - 0.0018 16.8 0.0 0.0028 16.2 0.0 1.2 1 0 0 1 1 1 1 HI0933-like protein SE PF08491.5 KLO12611.1 - 0.0042 15.9 0.0 0.11 11.3 0.0 2.1 2 0 0 2 2 2 1 Squalene epoxidase NAD_binding_7 PF13241.1 KLO12611.1 - 0.014 15.6 0.0 0.032 14.5 0.0 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding 3HCDH_N PF02737.13 KLO12611.1 - 0.017 14.8 0.0 0.033 13.8 0.0 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_binding_2 PF00890.19 KLO12611.1 - 0.017 13.9 0.0 0.027 13.3 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain AT_hook PF02178.14 KLO12612.1 - 5.3e-05 22.4 56.4 0.0078 15.7 1.8 4.9 5 0 0 5 5 5 4 AT hook motif PRKCSH PF07915.8 KLO12613.1 - 2.2e-13 50.7 0.4 2.2e-13 50.7 0.3 1.8 2 0 0 2 2 2 1 Glucosidase II beta subunit-like protein PRKCSH_1 PF13015.1 KLO12613.1 - 9.4e-05 21.9 0.0 0.0004 19.8 0.0 1.8 2 0 0 2 2 2 1 Glucosidase II beta subunit-like protein Pkinase PF00069.20 KLO12614.1 - 1e-53 182.1 0.0 7.7e-53 179.2 0.0 1.9 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 KLO12614.1 - 5.4e-25 87.9 0.0 8.4e-25 87.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 KLO12614.1 - 0.0035 17.0 0.3 0.0091 15.7 0.2 2.1 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.1 KLO12614.1 - 0.0038 16.2 0.0 0.0065 15.4 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pr_beta_C PF12465.3 KLO12616.1 - 0.093 12.0 0.8 0.17 11.1 0.6 1.4 1 0 0 1 1 1 0 Proteasome beta subunits C terminal 2OG-FeII_Oxy_3 PF13640.1 KLO12617.1 - 8.8e-09 35.7 0.0 1.8e-08 34.7 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_4 PF13661.1 KLO12617.1 - 5.4e-06 25.9 0.0 1e-05 25.0 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.15 KLO12617.1 - 0.00081 19.6 0.0 0.0018 18.5 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily RTA1 PF04479.8 KLO12618.1 - 1.5e-37 129.2 1.1 2.2e-37 128.7 0.8 1.1 1 0 0 1 1 1 1 RTA1 like protein RTA1 PF04479.8 KLO12619.1 - 7.6e-42 143.3 5.1 1.3e-41 142.6 3.5 1.2 1 0 0 1 1 1 1 RTA1 like protein 7TM_GPCR_Str PF10326.4 KLO12619.1 - 0.0077 15.3 9.3 0.062 12.4 6.5 2.3 1 1 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Str DUF1517 PF07466.6 KLO12619.1 - 0.53 9.2 2.3 0.51 9.2 0.2 2.0 2 1 0 2 2 2 0 Protein of unknown function (DUF1517) ATP-synt_8 PF00895.15 KLO12619.1 - 0.76 10.0 7.7 1.8 8.8 0.1 3.4 3 1 0 3 3 3 0 ATP synthase protein 8 Kelch_4 PF13418.1 KLO12620.1 - 2.3e-19 68.8 4.8 1.3e-11 44.0 0.0 6.0 6 0 0 6 6 6 2 Galactose oxidase, central domain Kelch_3 PF13415.1 KLO12620.1 - 1.5e-18 66.4 13.6 6.5e-05 22.9 0.0 7.1 7 0 0 7 7 7 4 Galactose oxidase, central domain Kelch_6 PF13964.1 KLO12620.1 - 4.1e-13 48.8 0.4 4.8e-05 23.3 0.0 4.6 5 0 0 5 5 5 3 Kelch motif Kelch_1 PF01344.20 KLO12620.1 - 4.2e-13 48.5 0.3 5.4e-07 29.0 0.0 3.7 3 0 0 3 3 3 3 Kelch motif Kelch_5 PF13854.1 KLO12620.1 - 5.1e-10 39.0 1.3 0.018 15.0 0.1 5.1 5 0 0 5 5 5 2 Kelch motif Kelch_2 PF07646.10 KLO12620.1 - 9.5e-06 25.1 4.1 0.023 14.4 0.1 4.6 5 0 0 5 5 5 2 Kelch motif DEAD PF00270.24 KLO12621.1 - 4.9e-45 153.0 0.0 9.9e-45 152.0 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KLO12621.1 - 1.1e-26 92.4 0.0 2.4e-26 91.3 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 KLO12621.1 - 0.00076 19.3 0.0 0.0041 16.9 0.0 2.0 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit PBP1_TM PF14812.1 KLO12621.1 - 5.7 7.3 10.1 9.7 6.5 7.0 1.4 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal RNA_pol_Rpb1_1 PF04997.7 KLO12622.1 - 8.9e-118 393.3 0.0 1.3e-117 392.8 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_5 PF04998.12 KLO12622.1 - 3.3e-101 338.2 0.0 5.2e-101 337.5 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.15 KLO12622.1 - 3.8e-68 228.6 0.0 8.8e-68 227.4 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_6 PF04992.9 KLO12622.1 - 4.6e-65 218.8 0.1 1.1e-64 217.6 0.1 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 6 RNA_pol_Rpb1_3 PF04983.13 KLO12622.1 - 6.7e-52 175.3 0.0 6.6e-51 172.1 0.0 2.6 3 0 0 3 3 3 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_7 PF04990.7 KLO12622.1 - 5.4e-46 155.6 0.2 1.2e-45 154.4 0.1 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 7 RNA_pol_Rpb1_4 PF05000.12 KLO12622.1 - 6.7e-35 119.1 0.0 1.5e-34 117.9 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 RNA_pol_Rpb1_R PF05001.8 KLO12622.1 - 0.0001 22.1 194.8 0.06 13.4 3.1 13.4 9 2 5 14 14 14 12 RNA polymerase Rpb1 C-terminal repeat TRAPPC10 PF12584.3 KLO12624.1 - 1.1e-22 80.1 0.0 2.4e-22 79.0 0.0 1.6 1 0 0 1 1 1 1 Trafficking protein particle complex subunit 10, TRAPPC10 ALG3 PF05208.8 KLO12625.1 - 3.1e-114 382.0 15.0 4.7e-114 381.4 10.4 1.2 1 0 0 1 1 1 1 ALG3 protein Cellulase PF00150.13 KLO12626.1 - 3.3e-16 59.3 0.3 7.7e-16 58.1 0.2 1.5 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) DUF1042 PF06294.6 KLO12626.1 - 0.073 12.6 0.0 0.18 11.3 0.0 1.6 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1042) PIG-H PF10181.4 KLO12627.1 - 6.8e-11 41.6 0.0 9.6e-11 41.1 0.0 1.2 1 0 0 1 1 1 1 GPI-GlcNAc transferase complex, PIG-H component Ist1 PF03398.9 KLO12628.1 - 4.6e-35 120.4 0.2 7.9e-35 119.7 0.1 1.4 1 0 0 1 1 1 1 Regulator of Vps4 activity in the MVB pathway RabGAP-TBC PF00566.13 KLO12628.1 - 3.7e-17 62.5 0.0 3.9e-14 52.6 0.0 2.5 2 0 0 2 2 2 2 Rab-GTPase-TBC domain GPI-anchored PF10342.4 KLO12629.1 - 6.5e-11 42.5 5.3 6.5e-11 42.5 3.7 1.7 2 0 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Tissue_fac PF01108.12 KLO12629.1 - 0.01 15.5 0.1 0.015 15.0 0.1 1.3 1 0 0 1 1 1 0 Tissue factor RAP1 PF07218.6 KLO12629.1 - 2.1 6.3 6.9 2.4 6.1 4.8 1.0 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Asp PF00026.18 KLO12630.1 - 4.7e-46 157.4 2.6 1e-45 156.4 1.8 1.5 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 KLO12630.1 - 3.4e-05 23.8 2.4 0.00039 20.4 0.6 2.8 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal TAXi_C PF14541.1 KLO12630.1 - 0.11 12.1 1.0 4 6.9 0.1 2.3 2 0 0 2 2 2 0 Xylanase inhibitor C-terminal HEAT_2 PF13646.1 KLO12633.1 - 1.1e-17 64.0 4.9 9e-07 29.0 0.0 5.9 5 0 0 5 5 5 3 HEAT repeats HEAT PF02985.17 KLO12633.1 - 2.9e-16 58.0 24.5 0.00012 21.8 0.1 9.8 11 0 0 11 11 11 4 HEAT repeat Ipi1_N PF12333.3 KLO12633.1 - 0.015 15.2 7.6 0.039 13.9 0.0 4.2 5 0 0 5 5 5 0 Rix1 complex component involved in 60S ribosome maturation HEAT_EZ PF13513.1 KLO12633.1 - 0.053 14.0 17.0 4.4 7.9 0.0 7.1 7 2 1 8 8 8 0 HEAT-like repeat Adaptin_N PF01602.15 KLO12633.1 - 0.073 11.3 0.2 1.7 6.9 0.0 2.6 2 1 0 2 2 2 0 Adaptin N terminal region HEAT_PBS PF03130.11 KLO12633.1 - 0.14 12.7 1.5 11 6.8 0.0 4.2 4 0 0 4 4 4 0 PBS lyase HEAT-like repeat DUF1908 PF08926.6 KLO12633.1 - 4.1 6.0 8.6 9.1 4.9 5.6 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF1908) DUF4632 PF15451.1 KLO12634.1 - 0.021 14.7 0.1 0.039 13.8 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4632) Aminotran_1_2 PF00155.16 KLO12635.1 - 4.4e-83 279.2 0.0 4.9e-83 279.0 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II zf-AN1 PF01428.11 KLO12636.1 - 3.2e-10 39.7 5.1 4.5e-10 39.2 3.5 1.2 1 0 0 1 1 1 1 AN1-like Zinc finger IBR PF01485.16 KLO12636.1 - 0.018 14.8 2.5 0.025 14.4 1.7 1.4 1 0 0 1 1 1 0 IBR domain GPI-anchored PF10342.4 KLO12637.1 - 3.7e-08 33.7 0.2 4.6e-08 33.4 0.1 1.1 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Dicer_dimer PF03368.9 KLO12637.1 - 0.073 12.8 0.0 0.1 12.3 0.0 1.2 1 0 0 1 1 1 0 Dicer dimerisation domain Ion_trans PF00520.26 KLO12638.1 - 0.0036 16.5 1.0 0.0058 15.9 0.7 1.3 1 0 0 1 1 1 1 Ion transport protein TMEM192 PF14802.1 KLO12638.1 - 1.3 7.7 3.9 4.8 5.9 0.1 2.6 2 1 1 3 3 3 0 TMEM192 family SNARE PF05739.14 KLO12639.1 - 7.8e-13 47.9 8.1 2e-12 46.6 5.6 1.7 1 0 0 1 1 1 1 SNARE domain Syntaxin PF00804.20 KLO12639.1 - 7e-05 22.9 12.2 0.00084 19.4 2.9 2.6 2 1 0 2 2 2 2 Syntaxin PBP1_TM PF14812.1 KLO12639.1 - 0.0031 17.7 0.8 0.0031 17.7 0.6 2.4 2 2 0 2 2 1 1 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF3611 PF12263.3 KLO12639.1 - 0.008 15.5 1.4 0.017 14.4 0.9 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3611) MCPsignal PF00015.16 KLO12639.1 - 0.014 14.9 6.2 0.02 14.4 1.2 2.3 1 1 1 3 3 3 0 Methyl-accepting chemotaxis protein (MCP) signalling domain VirB8 PF04335.8 KLO12639.1 - 0.017 14.7 1.3 0.051 13.1 0.9 1.9 1 0 0 1 1 1 0 VirB8 protein DUF912 PF06024.7 KLO12639.1 - 0.037 14.0 0.2 0.11 12.5 0.2 1.9 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) EMP24_GP25L PF01105.19 KLO12639.1 - 0.052 13.2 7.3 0.079 12.6 3.6 2.4 1 1 1 2 2 2 0 emp24/gp25L/p24 family/GOLD Use1 PF09753.4 KLO12639.1 - 0.057 12.8 6.8 0.099 12.0 4.7 1.4 1 1 0 1 1 1 0 Membrane fusion protein Use1 DUF3753 PF12575.3 KLO12639.1 - 0.06 13.1 1.4 0.13 12.0 1.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3753) DUF1664 PF07889.7 KLO12639.1 - 0.075 12.8 6.2 0.48 10.2 0.9 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) DUF805 PF05656.9 KLO12639.1 - 0.082 12.7 1.3 0.12 12.1 0.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF805) Tweety PF04906.8 KLO12639.1 - 0.09 11.1 2.5 0.047 12.1 0.4 1.5 2 0 0 2 2 2 0 Tweety Laminin_II PF06009.7 KLO12639.1 - 0.15 11.8 7.0 0.17 11.6 1.2 2.5 2 1 0 2 2 2 0 Laminin Domain II DUF4337 PF14235.1 KLO12639.1 - 0.3 10.9 11.4 2 8.2 1.5 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4337) DUF3035 PF11233.3 KLO12639.1 - 0.36 10.8 9.6 0.77 9.7 0.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3035) Syntaxin_2 PF14523.1 KLO12639.1 - 0.4 10.7 12.8 0.12 12.3 2.2 2.7 2 1 0 2 2 2 0 Syntaxin-like protein DUF3708 PF12501.3 KLO12639.1 - 0.41 10.4 1.9 0.7 9.7 0.7 1.8 1 1 0 1 1 1 0 Phosphate ATP-binding cassette transporter Baculo_PEP_C PF04513.7 KLO12639.1 - 0.41 10.4 4.6 1.6 8.5 1.1 2.3 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF607 PF04678.8 KLO12639.1 - 0.66 9.8 3.9 1.3 8.9 1.6 2.2 1 1 1 2 2 2 0 Protein of unknown function, DUF607 Prominin PF05478.6 KLO12639.1 - 0.8 7.1 11.5 0.35 8.3 2.3 2.1 1 1 1 2 2 2 0 Prominin FH2 PF02181.18 KLO12639.1 - 1.3 7.8 7.4 0.82 8.4 0.3 2.1 2 0 0 2 2 2 0 Formin Homology 2 Domain FlaC_arch PF05377.6 KLO12639.1 - 1.8 8.4 12.0 0.53 10.2 0.3 4.5 5 2 1 6 6 4 0 Flagella accessory protein C (FlaC) Syntaxin-6_N PF09177.6 KLO12639.1 - 5.1 7.5 16.1 7 7.1 2.9 3.5 2 1 2 4 4 4 0 Syntaxin 6, N-terminal YtxH PF12732.2 KLO12639.1 - 6.1 7.2 9.0 7.4 7.0 0.5 3.0 2 1 0 2 2 2 0 YtxH-like protein Lyase_1 PF00206.15 KLO12640.1 - 8.2e-101 337.2 0.0 1.5e-100 336.4 0.0 1.4 2 0 0 2 2 2 1 Lyase ASL_C2 PF14698.1 KLO12640.1 - 9.3e-28 96.1 0.2 2e-27 95.0 0.1 1.6 1 0 0 1 1 1 1 Argininosuccinate lyase C-terminal DUF3176 PF11374.3 KLO12642.1 - 0.0041 16.9 5.8 0.16 11.8 0.6 2.9 2 0 0 2 2 2 2 Protein of unknown function (DUF3176) F-box PF00646.28 KLO12644.1 - 4.9e-05 22.8 0.3 0.00012 21.6 0.2 1.7 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 KLO12644.1 - 0.023 14.4 0.1 0.059 13.0 0.0 1.7 1 0 0 1 1 1 0 F-box-like NAD_binding_4 PF07993.7 KLO12645.1 - 7.7e-33 113.4 0.0 1.1e-32 112.8 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.23 KLO12645.1 - 6.7e-25 87.3 0.0 1.3e-24 86.3 0.0 1.5 1 1 0 1 1 1 1 AMP-binding enzyme Epimerase PF01370.16 KLO12645.1 - 1.2e-09 37.9 0.0 2e-09 37.2 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.20 KLO12645.1 - 1.9e-06 28.0 0.2 5.4e-06 26.5 0.0 1.9 2 0 0 2 2 2 1 Phosphopantetheine attachment site 3Beta_HSD PF01073.14 KLO12645.1 - 0.14 10.8 0.0 0.48 9.0 0.0 1.7 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Lipase_3 PF01764.20 KLO12646.1 - 1.1e-21 76.9 0.0 1.5e-21 76.5 0.0 1.2 1 0 0 1 1 1 1 Lipase (class 3) Aldo_ket_red PF00248.16 KLO12648.1 - 9.3e-65 218.2 0.0 1.1e-64 218.0 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Adaptin_N PF01602.15 KLO12649.1 - 0.065 11.5 0.1 0.67 8.2 0.0 2.1 2 0 0 2 2 2 0 Adaptin N terminal region SET PF00856.23 KLO12650.1 - 8.6e-10 39.1 0.0 5.4e-09 36.5 0.0 2.2 2 0 0 2 2 2 1 SET domain TPR_11 PF13414.1 KLO12650.1 - 0.026 14.1 0.1 0.061 12.9 0.1 1.6 1 0 0 1 1 1 0 TPR repeat DUF3127 PF11325.3 KLO12650.1 - 0.17 11.8 0.1 0.81 9.7 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3127) DUF3176 PF11374.3 KLO12651.1 - 0.22 11.4 4.5 0.53 10.1 0.5 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3176) Tet_JBP PF12851.2 KLO12655.1 - 4.6e-05 22.7 0.0 5.8e-05 22.4 0.0 1.2 1 0 0 1 1 1 1 Oxygenase domain of the 2OGFeDO superfamily DUF2088 PF09861.4 KLO12655.1 - 0.13 11.2 0.0 0.28 10.1 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF2088) LBR_tudor PF09465.5 KLO12656.1 - 0.066 12.8 0.0 0.15 11.6 0.0 1.6 1 0 0 1 1 1 0 Lamin-B receptor of TUDOR domain DUF3176 PF11374.3 KLO12657.1 - 0.057 13.3 2.4 8 6.3 0.0 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3176) WAPL PF07814.8 KLO12659.1 - 0.13 10.9 0.2 3.8 6.1 0.0 2.2 2 0 0 2 2 2 0 Wings apart-like protein regulation of heterochromatin TPR_11 PF13414.1 KLO12661.1 - 8.3e-14 50.9 5.9 2.5e-12 46.2 0.3 2.8 2 1 2 4 4 4 3 TPR repeat TPR_16 PF13432.1 KLO12661.1 - 1.1e-07 32.3 4.8 0.00029 21.4 0.2 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.12 KLO12661.1 - 2e-07 30.3 6.8 0.19 11.7 0.5 3.8 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.23 KLO12661.1 - 2e-06 27.1 3.1 0.039 13.5 0.1 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.1 KLO12661.1 - 6.3e-05 23.2 2.7 0.016 15.7 0.2 2.9 1 1 1 2 2 2 1 Tetratricopeptide repeat Apc3 PF12895.2 KLO12661.1 - 8.6e-05 22.6 1.5 0.00019 21.5 1.1 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.1 KLO12661.1 - 0.00026 20.8 3.9 0.15 12.0 0.4 3.4 2 1 1 3 3 3 2 Tetratricopeptide repeat SET PF00856.23 KLO12661.1 - 0.00082 19.7 0.0 0.083 13.1 0.0 3.1 2 1 1 3 3 3 1 SET domain TPR_6 PF13174.1 KLO12661.1 - 0.00099 19.4 2.3 0.084 13.3 0.3 2.9 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.1 KLO12661.1 - 0.024 14.3 0.0 0.67 9.8 0.0 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_9 PF13371.1 KLO12661.1 - 0.039 13.7 0.7 0.14 11.9 0.1 2.1 1 1 1 2 2 2 0 Tetratricopeptide repeat SAF PF08666.7 KLO12661.1 - 0.046 14.1 0.0 0.63 10.4 0.0 2.5 2 0 0 2 2 2 0 SAF domain TPR_19 PF14559.1 KLO12661.1 - 0.082 13.2 5.8 0.15 12.4 1.9 2.4 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_7 PF13176.1 KLO12661.1 - 0.41 10.5 3.0 22 5.1 0.1 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat CRA PF06589.6 KLO12663.1 - 0.044 13.1 0.2 0.12 11.6 0.0 1.8 2 0 0 2 2 2 0 Circumsporozoite-related antigen (CRA) Transketolase_N PF00456.16 KLO12664.1 - 2.1e-17 62.9 0.6 2e-16 59.7 0.4 2.0 1 1 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transketolase_C PF02780.15 KLO12664.1 - 5.1e-09 36.1 0.0 1.1e-08 35.0 0.0 1.5 1 0 0 1 1 1 1 Transketolase, C-terminal domain Transket_pyr PF02779.19 KLO12664.1 - 1.1e-05 25.0 0.3 2.4e-05 23.9 0.1 1.7 2 0 0 2 2 2 1 Transketolase, pyrimidine binding domain E1_dh PF00676.15 KLO12664.1 - 0.00084 18.1 0.0 0.0014 17.4 0.0 1.2 1 0 0 1 1 1 1 Dehydrogenase E1 component TPP_enzyme_C PF02775.16 KLO12664.1 - 0.00098 18.7 0.1 0.0044 16.6 0.1 2.0 1 1 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain UBX PF00789.15 KLO12666.1 - 3.7e-07 30.1 0.0 6.8e-07 29.2 0.0 1.4 1 0 0 1 1 1 1 UBX domain Thioredoxin_7 PF13899.1 KLO12666.1 - 3e-05 23.9 0.0 7e-05 22.7 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin-like DUF4246 PF14033.1 KLO12666.1 - 0.023 13.3 0.0 0.14 10.7 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF4246) PgaD PF13994.1 KLO12667.1 - 0.023 14.2 1.0 0.048 13.1 0.7 1.4 1 0 0 1 1 1 0 PgaD-like protein PgaD PF13994.1 KLO12669.1 - 0.00029 20.3 0.3 0.00064 19.2 0.2 1.5 1 0 0 1 1 1 1 PgaD-like protein DUF1573 PF07610.6 KLO12669.1 - 0.072 12.6 0.1 0.16 11.5 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1573) PARP PF00644.15 KLO12670.1 - 5.5e-10 39.0 2.9 4.3e-09 36.1 0.5 2.7 1 1 1 2 2 2 1 Poly(ADP-ribose) polymerase catalytic domain zf-FCS PF06467.9 KLO12670.1 - 0.0065 16.0 1.2 0.0065 16.0 0.8 5.3 5 0 0 5 5 5 3 MYM-type Zinc finger with FCS sequence motif Ecl1 PF12855.2 KLO12670.1 - 0.026 13.7 4.9 2.1 7.6 0.4 3.1 2 0 0 2 2 2 0 Life-span regulatory factor DUF3220 PF11516.3 KLO12673.1 - 0.077 12.9 0.0 0.16 11.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3120) Syntaxin-6_N PF09177.6 KLO12674.1 - 0.0043 17.4 3.8 0.0061 16.9 2.6 1.2 1 0 0 1 1 1 1 Syntaxin 6, N-terminal Peptidase_C6 PF00851.13 KLO12674.1 - 0.0085 14.7 0.4 0.0093 14.6 0.3 1.0 1 0 0 1 1 1 1 Helper component proteinase ATP-synt_D PF01813.12 KLO12674.1 - 0.025 14.1 0.6 0.037 13.5 0.2 1.5 1 1 0 1 1 1 0 ATP synthase subunit D Z1 PF10593.4 KLO12674.1 - 0.026 13.7 0.5 0.029 13.5 0.3 1.1 1 0 0 1 1 1 0 Z1 domain Spectrin PF00435.16 KLO12674.1 - 0.045 14.0 4.8 0.063 13.5 3.4 1.1 1 0 0 1 1 1 0 Spectrin repeat GAS PF13851.1 KLO12674.1 - 0.051 12.7 3.9 0.066 12.4 2.7 1.1 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding ApoL PF05461.6 KLO12674.1 - 0.1 11.8 0.2 0.12 11.6 0.1 1.1 1 0 0 1 1 1 0 Apolipoprotein L APG17 PF04108.7 KLO12674.1 - 0.14 10.9 3.6 0.15 10.8 2.5 1.0 1 0 0 1 1 1 0 Autophagy protein Apg17 DUF342 PF03961.8 KLO12674.1 - 0.17 10.2 0.4 0.19 10.1 0.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Seryl_tRNA_N PF02403.17 KLO12674.1 - 0.33 10.9 3.3 0.48 10.4 2.3 1.2 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain DUF1664 PF07889.7 KLO12674.1 - 0.72 9.6 3.4 1.4 8.7 2.3 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) DUF4200 PF13863.1 KLO12674.1 - 2.7 7.9 8.3 3.1 7.7 2.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) IncA PF04156.9 KLO12674.1 - 3.5 7.1 6.3 4.4 6.8 4.3 1.1 1 0 0 1 1 1 0 IncA protein HCaRG PF07258.9 KLO12675.1 - 0.034 13.7 0.4 0.065 12.7 0.1 1.7 2 0 0 2 2 2 0 HCaRG protein DBINO PF13892.1 KLO12675.1 - 0.11 12.4 0.1 0.11 12.4 0.1 1.8 2 0 0 2 2 2 0 DNA-binding domain Exonuc_VII_S PF02609.11 KLO12675.1 - 0.2 11.4 1.4 2.8 7.7 0.1 2.5 2 0 0 2 2 2 0 Exonuclease VII small subunit DUF948 PF06103.6 KLO12675.1 - 0.34 10.8 1.5 1.6 8.6 0.1 2.6 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) V-SNARE PF05008.10 KLO12675.1 - 0.83 9.8 4.7 21 5.3 0.0 3.6 3 1 0 3 3 3 0 Vesicle transport v-SNARE protein N-terminus DUF3043 PF11241.3 KLO12676.1 - 0.076 12.5 0.5 0.12 12.0 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3043) Fzo_mitofusin PF04799.8 KLO12677.1 - 0.0042 16.4 3.5 0.41 10.0 0.1 2.7 3 0 0 3 3 3 2 fzo-like conserved region NEP PF10167.4 KLO12677.1 - 0.05 13.3 2.8 3.3 7.4 0.0 3.1 4 0 0 4 4 4 0 Uncharacterised conserved protein Streptin-Immun PF11083.3 KLO12677.1 - 0.11 12.4 3.3 0.66 10.0 0.7 2.5 2 0 0 2 2 2 0 Lantibiotic streptin immunity protein DASH_Duo1 PF08651.5 KLO12677.1 - 0.2 11.2 2.2 0.57 9.7 0.1 2.8 3 0 0 3 3 3 0 DASH complex subunit Duo1 YPEB PF14620.1 KLO12677.1 - 0.32 9.9 2.8 19 4.1 1.4 3.0 2 1 0 2 2 2 0 YpeB sporulation ADIP PF11559.3 KLO12677.1 - 0.6 10.0 4.6 2.6 7.9 0.7 2.4 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding Mst1_SARAH PF11629.3 KLO12678.1 - 0.0067 16.2 1.2 0.14 11.9 0.4 2.7 2 0 0 2 2 2 1 C terminal SARAH domain of Mst1 Spc24 PF08286.6 KLO12678.1 - 0.022 14.4 3.2 0.11 12.2 0.1 3.2 3 1 0 3 3 3 0 Spc24 subunit of Ndc80 Apolipoprotein PF01442.13 KLO12678.1 - 0.037 13.5 1.0 0.14 11.6 0.6 2.0 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain ATG16 PF08614.6 KLO12678.1 - 0.081 12.7 4.7 0.049 13.4 0.7 2.2 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) FlxA PF14282.1 KLO12678.1 - 0.085 12.8 3.7 0.32 10.9 0.0 2.7 3 0 0 3 3 3 0 FlxA-like protein PEP-utilisers_N PF05524.8 KLO12678.1 - 0.12 12.1 0.7 28 4.5 0.0 3.1 2 1 1 3 3 3 0 PEP-utilising enzyme, N-terminal CENP-F_leu_zip PF10473.4 KLO12678.1 - 0.21 11.4 8.4 0.34 10.7 2.7 2.6 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Dict-STAT-coil PF09267.5 KLO12678.1 - 0.28 11.4 2.5 17 5.7 0.0 3.0 3 0 0 3 3 3 0 Dictyostelium STAT, coiled coil TBPIP PF07106.8 KLO12678.1 - 0.79 9.2 5.7 0.98 8.9 0.7 2.7 1 1 1 3 3 3 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Syntaxin PF00804.20 KLO12678.1 - 3.3 7.9 8.9 0.65 10.1 0.2 3.0 2 2 1 3 3 3 0 Syntaxin Erp_C PF06780.6 KLO12678.1 - 4.4 7.1 7.1 0.76 9.6 0.4 2.8 2 1 0 3 3 3 0 Erp protein C-terminus IncA PF04156.9 KLO12678.1 - 6.1 6.4 8.6 1.5 8.3 1.9 2.5 1 1 0 2 2 2 0 IncA protein DUF1664 PF07889.7 KLO12678.1 - 6.5 6.5 7.2 34 4.2 0.2 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) Zn_clus PF00172.13 KLO12681.1 - 0.0018 18.1 11.9 0.0041 17.0 8.3 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Dickkopf_N PF04706.7 KLO12681.1 - 3.7 7.8 10.2 7.4 6.8 6.3 2.1 1 1 1 2 2 2 0 Dickkopf N-terminal cysteine-rich region HTH_Tnp_Tc5 PF03221.11 KLO12683.1 - 0.031 14.0 0.0 2.1 8.2 0.0 2.4 2 0 0 2 2 2 0 Tc5 transposase DNA-binding domain DDE_1 PF03184.14 KLO12684.1 - 1.9e-29 102.3 0.0 2.3e-29 102.0 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_3 PF13358.1 KLO12684.1 - 0.00028 20.6 0.0 0.00045 19.9 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HAND PF09110.6 KLO12685.1 - 0.047 14.0 0.9 0.12 12.8 0.6 1.8 1 0 0 1 1 1 0 HAND CDP-OH_P_transf PF01066.16 KLO12688.1 - 1.3e-18 67.0 2.6 1.3e-18 67.0 1.8 1.6 2 0 0 2 2 2 1 CDP-alcohol phosphatidyltransferase UAA PF08449.6 KLO12689.1 - 6.4e-67 225.6 10.7 7.2e-67 225.4 7.4 1.0 1 0 0 1 1 1 1 UAA transporter family TPT PF03151.11 KLO12689.1 - 0.012 15.2 13.7 0.024 14.2 5.1 2.9 2 1 0 2 2 2 0 Triose-phosphate Transporter family DUF914 PF06027.7 KLO12689.1 - 0.015 14.1 0.4 0.015 14.1 0.3 1.6 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF914) EamA PF00892.15 KLO12689.1 - 0.49 10.4 22.6 0.27 11.2 4.5 3.4 2 2 2 4 4 4 0 EamA-like transporter family Nup35_RRM PF05172.8 KLO12690.1 - 2.6e-05 23.8 0.0 0.00044 19.9 0.0 2.2 1 1 0 1 1 1 1 Nup53/35/40-type RNA recognition motif Nup35_RRM_2 PF14605.1 KLO12690.1 - 0.09 12.5 0.0 0.22 11.3 0.0 1.6 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif Rho_Binding PF08912.6 KLO12691.1 - 0.019 15.2 4.9 0.019 15.2 3.4 3.3 2 1 1 3 3 3 0 Rho Binding Filament PF00038.16 KLO12691.1 - 0.037 13.5 27.4 0.076 12.4 4.1 3.2 2 1 1 3 3 3 0 Intermediate filament protein Atg14 PF10186.4 KLO12691.1 - 0.44 9.4 0.0 0.44 9.4 0.0 3.6 2 1 1 3 3 3 0 UV radiation resistance protein and autophagy-related subunit 14 Fib_alpha PF08702.5 KLO12691.1 - 0.63 10.1 17.6 2.5 8.2 5.2 4.0 2 1 2 4 4 4 0 Fibrinogen alpha/beta chain family DUF4047 PF13256.1 KLO12691.1 - 0.9 9.5 16.8 0.26 11.2 0.8 3.1 1 1 2 3 3 3 0 Domain of unknown function (DUF4047) TPR_MLP1_2 PF07926.7 KLO12691.1 - 1.6 8.4 34.4 0.055 13.2 12.6 3.6 2 1 1 3 3 3 0 TPR/MLP1/MLP2-like protein ADIP PF11559.3 KLO12691.1 - 5.8 6.8 34.0 39 4.1 0.0 4.1 3 1 0 3 3 3 0 Afadin- and alpha -actinin-Binding CENP-Q PF13094.1 KLO12691.1 - 7.8 6.5 33.1 1.9 8.4 3.9 3.8 2 1 1 3 3 3 0 CENP-Q, a CENPA-CAD centromere complex subunit DUF948 PF06103.6 KLO12691.1 - 8.8 6.2 8.3 3 7.7 0.4 3.7 2 1 3 5 5 5 0 Bacterial protein of unknown function (DUF948) NMO PF03060.10 KLO12692.1 - 9.5e-70 235.3 0.2 1.1e-69 235.0 0.1 1.1 1 0 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.20 KLO12692.1 - 0.0005 19.0 0.0 0.12 11.2 0.0 2.5 2 1 0 2 2 2 2 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.13 KLO12692.1 - 0.11 11.2 2.2 0.18 10.6 1.5 1.2 1 0 0 1 1 1 0 FMN-dependent dehydrogenase Pkinase PF00069.20 KLO12693.1 - 2e-64 217.2 0.0 2.9e-64 216.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KLO12693.1 - 1.5e-35 122.5 0.0 2.2e-35 121.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KLO12693.1 - 4.5e-07 29.1 0.0 7.5e-07 28.3 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 KLO12693.1 - 0.00039 19.5 0.3 0.0017 17.4 0.0 2.0 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KLO12693.1 - 0.0024 17.6 0.2 0.0049 16.6 0.1 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.17 KLO12693.1 - 0.019 14.3 0.3 0.059 12.7 0.0 2.0 2 0 0 2 2 2 0 RIO1 family Guanylate_kin PF00625.16 KLO12694.1 - 2.2e-66 222.8 0.0 2.6e-66 222.5 0.0 1.0 1 0 0 1 1 1 1 Guanylate kinase AAA_33 PF13671.1 KLO12694.1 - 2.5e-06 27.4 0.0 8.9e-06 25.6 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 KLO12694.1 - 4.3e-06 26.8 0.1 8.6e-06 25.8 0.1 1.8 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 KLO12694.1 - 4e-05 23.7 0.0 0.00018 21.6 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 KLO12694.1 - 0.00014 22.6 0.0 0.00025 21.8 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 KLO12694.1 - 0.00058 20.1 0.0 0.0022 18.3 0.0 1.9 1 1 0 1 1 1 1 AAA domain DUF258 PF03193.11 KLO12694.1 - 0.00092 18.4 0.0 0.0014 17.8 0.0 1.4 1 1 0 1 1 1 1 Protein of unknown function, DUF258 RNA_helicase PF00910.17 KLO12694.1 - 0.0016 18.5 0.0 0.0027 17.8 0.0 1.4 1 0 0 1 1 1 1 RNA helicase NACHT PF05729.7 KLO12694.1 - 0.002 17.8 0.0 0.014 15.0 0.0 2.0 2 0 0 2 2 2 1 NACHT domain MMR_HSR1 PF01926.18 KLO12694.1 - 0.002 18.0 0.0 0.0035 17.2 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_14 PF13173.1 KLO12694.1 - 0.0026 17.6 0.0 0.0051 16.7 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_10 PF12846.2 KLO12694.1 - 0.0034 16.8 0.0 0.018 14.4 0.0 1.9 2 0 0 2 2 2 1 AAA-like domain AAA PF00004.24 KLO12694.1 - 0.0053 16.9 0.1 0.1 12.7 0.1 2.2 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Arch_ATPase PF01637.13 KLO12694.1 - 0.01 15.5 0.0 0.015 15.0 0.0 1.6 1 1 0 1 1 1 0 Archaeal ATPase Miro PF08477.8 KLO12694.1 - 0.011 16.1 0.0 0.023 15.1 0.0 1.5 1 1 0 1 1 1 0 Miro-like protein AAA_29 PF13555.1 KLO12694.1 - 0.015 14.8 0.0 0.028 13.9 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_tran PF00005.22 KLO12694.1 - 0.019 15.2 0.0 0.024 14.9 0.0 1.5 1 1 0 1 1 1 0 ABC transporter AAA_5 PF07728.9 KLO12694.1 - 0.026 14.2 0.0 0.47 10.1 0.0 2.2 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_28 PF13521.1 KLO12694.1 - 0.036 14.0 0.1 0.14 12.1 0.0 1.9 2 1 0 2 2 2 0 AAA domain NTPase_1 PF03266.10 KLO12694.1 - 0.051 13.2 0.0 0.12 12.1 0.0 1.6 1 0 0 1 1 1 0 NTPase AAA_19 PF13245.1 KLO12694.1 - 0.082 12.6 0.0 0.2 11.4 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain AAA_24 PF13479.1 KLO12694.1 - 0.086 12.4 0.0 0.29 10.7 0.0 1.8 2 0 0 2 2 2 0 AAA domain MFS_1 PF07690.11 KLO12696.1 - 3.8e-17 62.0 6.1 4.4e-17 61.8 4.2 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KLO12696.1 - 0.00023 19.8 1.6 0.00025 19.7 0.6 1.3 1 1 0 1 1 1 1 Sugar (and other) transporter FtsX PF02687.16 KLO12696.1 - 0.013 15.3 2.1 0.013 15.3 1.4 1.5 1 1 0 1 1 1 0 FtsX-like permease family MFS_2 PF13347.1 KLO12696.1 - 0.083 11.2 2.5 0.1 10.9 1.7 1.2 1 0 0 1 1 1 0 MFS/sugar transport protein PACT_coil_coil PF10495.4 KLO12697.1 - 2.8e-10 39.9 0.5 8.1e-10 38.4 0.3 1.8 1 0 0 1 1 1 1 Pericentrin-AKAP-450 domain of centrosomal targeting protein DUF948 PF06103.6 KLO12697.1 - 0.075 12.9 2.1 1.7 8.5 0.1 3.0 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF948) TMF_DNA_bd PF12329.3 KLO12697.1 - 0.15 11.9 22.9 0.9 9.3 0.3 3.8 1 1 2 3 3 3 0 TATA element modulatory factor 1 DNA binding FUSC PF04632.7 KLO12697.1 - 0.44 8.9 14.8 0.28 9.5 9.3 1.4 1 1 0 1 1 1 0 Fusaric acid resistance protein family APG6 PF04111.7 KLO12697.1 - 0.59 9.1 24.6 0.25 10.3 4.7 2.5 1 1 1 2 2 2 0 Autophagy protein Apg6 TPR_MLP1_2 PF07926.7 KLO12697.1 - 0.63 9.7 24.5 0.46 10.2 5.1 3.0 2 1 0 3 3 3 0 TPR/MLP1/MLP2-like protein Fib_alpha PF08702.5 KLO12697.1 - 1.1 9.3 13.3 1.8 8.6 2.9 2.6 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family DUF3708 PF12501.3 KLO12697.1 - 2.3 8.0 7.6 1.8 8.4 0.9 2.6 1 1 1 2 2 2 0 Phosphate ATP-binding cassette transporter PA26 PF04636.8 KLO12697.1 - 2.6 6.6 8.7 1.6 7.3 4.7 1.6 1 1 1 2 2 2 0 PA26 p53-induced protein (sestrin) DUF1664 PF07889.7 KLO12697.1 - 5.9 6.7 6.5 1.7 8.4 1.1 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) Spc24 PF08286.6 KLO12697.1 - 5.9 6.6 14.1 9.2 5.9 2.5 2.7 1 1 0 2 2 2 0 Spc24 subunit of Ndc80 ThylakoidFormat PF11264.3 KLO12697.1 - 9.9 5.7 15.4 0.44 10.1 6.2 2.1 2 1 0 2 2 2 0 Thylakoid formation protein Vps5 PF09325.5 KLO12698.1 - 3.4e-56 190.1 7.1 5.5e-56 189.4 4.9 1.3 1 0 0 1 1 1 1 Vps5 C terminal like PX PF00787.19 KLO12698.1 - 1.7e-24 85.8 0.0 4.8e-24 84.3 0.0 1.8 1 0 0 1 1 1 1 PX domain TPR_11 PF13414.1 KLO12699.1 - 0.0071 15.9 0.4 0.013 15.0 0.3 1.4 1 0 0 1 1 1 1 TPR repeat MIT PF04212.13 KLO12699.1 - 0.01 15.7 0.5 0.022 14.6 0.3 1.5 1 0 0 1 1 1 0 MIT (microtubule interacting and transport) domain F-box PF00646.28 KLO12699.1 - 0.02 14.5 1.3 0.05 13.2 0.9 1.7 1 0 0 1 1 1 0 F-box domain TPR_1 PF00515.23 KLO12699.1 - 0.093 12.3 0.5 0.5 10.0 0.3 2.1 1 1 1 2 2 2 0 Tetratricopeptide repeat SAS4 PF15460.1 KLO12699.1 - 0.1 12.5 0.3 0.42 10.5 0.0 2.0 2 0 0 2 2 2 0 Something about silencing, SAS, complex subunit 4 TPR_2 PF07719.12 KLO12699.1 - 0.11 12.4 1.2 0.27 11.2 0.9 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat F-box-like PF12937.2 KLO12699.1 - 0.12 12.0 1.2 0.27 10.9 0.8 1.6 1 0 0 1 1 1 0 F-box-like DnaJ PF00226.26 KLO12700.1 - 2.3e-25 88.1 0.7 4.4e-25 87.1 0.5 1.5 1 0 0 1 1 1 1 DnaJ domain DUF1977 PF09320.6 KLO12700.1 - 6.2e-15 55.3 6.9 9.2e-15 54.8 3.5 2.2 2 1 0 2 2 2 1 Domain of unknown function (DUF1977) TPR_2 PF07719.12 KLO12700.1 - 0.083 12.8 0.2 0.27 11.2 0.1 1.9 1 0 0 1 1 1 0 Tetratricopeptide repeat Cyd_oper_YbgE PF09600.5 KLO12701.1 - 0.00055 20.0 0.2 0.00069 19.7 0.1 1.2 1 0 0 1 1 1 1 Cyd operon protein YbgE (Cyd_oper_YbgE) WD40 PF00400.27 KLO12702.1 - 6.9e-14 51.0 0.8 0.73 9.8 0.1 7.5 8 0 0 8 8 8 6 WD domain, G-beta repeat Ribosomal_L37ae PF01780.14 KLO12704.1 - 1.4e-40 137.0 8.5 1.6e-40 136.8 5.9 1.0 1 0 0 1 1 1 1 Ribosomal L37ae protein family Zn_Tnp_IS1595 PF12760.2 KLO12704.1 - 0.0019 17.9 3.2 0.0028 17.4 2.2 1.3 1 0 0 1 1 1 1 Transposase zinc-ribbon domain zf-BED PF02892.10 KLO12704.1 - 0.017 14.9 4.0 0.086 12.6 0.1 2.3 1 1 1 2 2 2 0 BED zinc finger NST1 PF13945.1 KLO12704.1 - 0.1 12.6 0.8 0.14 12.2 0.5 1.1 1 0 0 1 1 1 0 Salt tolerance down-regulator C1_1 PF00130.17 KLO12704.1 - 0.12 12.0 2.7 0.19 11.4 1.8 1.3 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) OrfB_Zn_ribbon PF07282.6 KLO12704.1 - 0.14 11.8 1.2 0.21 11.2 0.9 1.3 1 0 0 1 1 1 0 Putative transposase DNA-binding domain A2L_zn_ribbon PF08792.5 KLO12704.1 - 0.15 11.6 4.7 0.47 9.9 0.1 2.1 2 0 0 2 2 2 0 A2L zinc ribbon domain Zn-ribbon_8 PF09723.5 KLO12704.1 - 0.16 11.9 1.6 1.3 9.0 0.1 2.2 2 0 0 2 2 2 0 Zinc ribbon domain Elf1 PF05129.8 KLO12704.1 - 0.45 10.2 3.8 0.83 9.3 2.6 1.5 1 1 0 1 1 1 0 Transcription elongation factor Elf1 like zf-H2C2_2 PF13465.1 KLO12704.1 - 4.4 7.7 6.5 3.7 8.0 0.3 2.2 1 1 1 2 2 2 0 Zinc-finger double domain DUF1712 PF08217.6 KLO12705.1 - 2.9e-25 88.5 0.0 1.3e-22 79.8 0.0 2.1 2 0 0 2 2 2 2 Fungal domain of unknown function (DUF1712) UCH PF00443.24 KLO12706.1 - 7.5e-77 258.0 0.0 2.8e-76 256.1 0.0 1.8 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 KLO12706.1 - 4e-20 72.4 0.0 4.6e-11 42.7 0.0 2.3 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase DUSP PF06337.7 KLO12706.1 - 4.8e-12 46.1 0.0 1.2e-11 44.8 0.0 1.8 1 0 0 1 1 1 1 DUSP domain USP7_C2 PF14533.1 KLO12706.1 - 8.9e-05 22.0 0.0 0.00015 21.2 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-specific protease C-terminal zf-FPG_IleRS PF06827.9 KLO12706.1 - 0.055 13.1 0.5 4.7 6.9 0.0 2.4 2 0 0 2 2 2 0 Zinc finger found in FPG and IleRS Zn-ribbon_8 PF09723.5 KLO12706.1 - 0.44 10.5 2.4 2 8.4 0.3 2.4 2 0 0 2 2 2 0 Zinc ribbon domain Ank_2 PF12796.2 KLO12707.1 - 1.2e-13 51.1 0.2 1e-06 28.9 0.1 2.4 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.1 KLO12707.1 - 4.6e-11 41.8 0.7 0.0046 17.0 0.0 4.5 4 0 0 4 4 4 3 Ankyrin repeat Ank_4 PF13637.1 KLO12707.1 - 1.9e-10 40.9 0.9 1.1e-05 25.7 0.0 2.8 1 1 0 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.25 KLO12707.1 - 5.9e-10 38.4 4.9 0.00039 20.0 0.1 4.3 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.1 KLO12707.1 - 2.4e-08 33.9 1.5 0.0079 16.4 0.0 3.6 3 0 0 3 3 3 2 Ankyrin repeats (many copies) KilA-N PF04383.8 KLO12707.1 - 0.00031 20.3 0.4 0.0079 15.8 0.0 2.8 2 1 0 2 2 2 1 KilA-N domain FEZ PF07763.8 KLO12707.1 - 0.07 12.8 0.6 0.14 11.8 0.4 1.4 1 0 0 1 1 1 0 FEZ-like protein WD40 PF00400.27 KLO12708.1 - 1.5e-58 192.6 1.8 3.8e-11 42.4 0.1 7.4 7 0 0 7 7 7 7 WD domain, G-beta repeat PRP4 PF08799.6 KLO12708.1 - 4.1e-13 48.3 1.4 9.2e-13 47.2 1.0 1.6 1 0 0 1 1 1 1 pre-mRNA processing factor 4 (PRP4) like Nbas_N PF15492.1 KLO12708.1 - 4.3e-05 22.7 0.1 0.71 8.9 0.0 3.4 2 1 2 4 4 4 2 Neuroblastoma-amplified sequence, N terminal PMT PF02366.13 KLO12709.1 - 1.2e-81 273.6 14.2 2.7e-81 272.5 9.8 1.6 1 0 0 1 1 1 1 Dolichyl-phosphate-mannose-protein mannosyltransferase MIR PF02815.14 KLO12709.1 - 7.6e-19 67.9 6.7 1.7e-13 50.5 0.7 2.1 1 1 1 2 2 2 2 MIR domain PMT_2 PF13231.1 KLO12709.1 - 1.7e-06 28.0 12.6 1.7e-06 28.0 8.7 3.2 3 1 0 3 3 3 1 Dolichyl-phosphate-mannose-protein mannosyltransferase AT_hook PF02178.14 KLO12710.1 - 0.49 10.2 7.6 1.2 9.0 5.3 1.7 1 0 0 1 1 1 0 AT hook motif DAO PF01266.19 KLO12711.1 - 2.2e-42 145.2 0.0 2.6e-42 145.0 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KLO12711.1 - 8.1e-06 25.7 0.2 9.3e-05 22.3 0.6 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 KLO12711.1 - 9.9e-06 25.7 0.0 0.11 12.4 0.0 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.19 KLO12711.1 - 0.0023 17.0 0.0 0.19 10.7 0.0 2.7 3 0 0 3 3 3 1 Flavin containing amine oxidoreductase Thi4 PF01946.12 KLO12711.1 - 0.0024 17.0 0.2 0.004 16.2 0.2 1.3 1 0 0 1 1 1 1 Thi4 family Pyr_redox_2 PF07992.9 KLO12711.1 - 0.0079 16.0 0.1 0.012 15.4 0.1 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 KLO12711.1 - 0.009 15.7 0.7 0.15 11.7 0.1 2.4 2 0 0 2 2 2 1 FAD-NAD(P)-binding zf-CCCH PF00642.19 KLO12712.1 - 9.6e-12 44.2 25.2 0.00059 19.4 0.6 5.1 4 1 1 5 5 5 4 Zinc finger C-x8-C-x5-C-x3-H type (and similar) YbgS PF13985.1 KLO12712.1 - 0.02 14.7 4.3 0.07 13.0 3.0 1.9 1 0 0 1 1 1 0 YbgS-like protein SNAPc19 PF15497.1 KLO12712.1 - 0.11 12.7 1.4 0.27 11.4 1.0 1.6 1 0 0 1 1 1 0 snRNA-activating protein complex subunit 19, SNAPc subunit 19 Dak1 PF02733.12 KLO12713.1 - 3.2e-112 374.2 0.7 4.5e-112 373.8 0.5 1.1 1 0 0 1 1 1 1 Dak1 domain Dak2 PF02734.12 KLO12713.1 - 2.5e-39 134.7 0.7 4.7e-39 133.8 0.5 1.4 1 0 0 1 1 1 1 DAK2 domain TFIIS_M PF07500.9 KLO12715.1 - 3.5e-15 56.0 0.6 8.2e-15 54.8 0.4 1.6 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS), central domain SPOC PF07744.8 KLO12715.1 - 4.4e-06 27.1 0.0 9.4e-06 26.0 0.0 1.6 1 0 0 1 1 1 1 SPOC domain PHD PF00628.24 KLO12716.1 - 2.9e-08 33.2 1.2 5.8e-08 32.3 0.8 1.5 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.1 KLO12716.1 - 0.0016 17.7 0.0 0.0031 16.7 0.0 1.5 1 0 0 1 1 1 1 PHD-finger Med3 PF11593.3 KLO12716.1 - 0.62 9.2 12.9 0.65 9.1 8.9 1.0 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Mei5 PF10376.4 KLO12716.1 - 2.7 7.4 5.0 3.2 7.2 3.5 1.1 1 0 0 1 1 1 0 Double-strand recombination repair protein DUF572 PF04502.8 KLO12716.1 - 3.5 6.7 7.4 4.2 6.4 5.1 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) YolD PF08863.5 KLO12717.1 - 0.036 13.9 0.8 0.063 13.1 0.6 1.3 1 0 0 1 1 1 0 YolD-like protein Pkinase PF00069.20 KLO12719.1 - 1.1e-68 231.2 0.0 1.3e-68 230.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KLO12719.1 - 1.5e-52 178.2 0.0 2.1e-52 177.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KLO12719.1 - 0.00017 20.6 0.0 0.0014 17.6 0.0 2.0 2 0 0 2 2 2 1 Kinase-like YrbL-PhoP_reg PF10707.4 KLO12719.1 - 0.065 12.5 0.0 0.13 11.5 0.0 1.4 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Seadorna_VP7 PF07387.6 KLO12719.1 - 0.087 11.6 0.1 0.14 11.0 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 RIO1 PF01163.17 KLO12719.1 - 0.099 11.9 0.0 0.19 11.0 0.0 1.4 1 0 0 1 1 1 0 RIO1 family DUF2450 PF10475.4 KLO12720.1 - 0.0033 16.3 0.5 0.0042 16.0 0.3 1.1 1 0 0 1 1 1 1 Protein of unknown function N-terminal domain (DUF2450) Fib_alpha PF08702.5 KLO12720.1 - 0.011 15.8 0.5 0.016 15.3 0.4 1.1 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family BBP1_C PF15272.1 KLO12720.1 - 0.036 13.6 2.5 0.3 10.5 0.3 2.1 1 1 1 2 2 2 0 Spindle pole body component BBP1, C-terminal BicD PF09730.4 KLO12720.1 - 0.055 11.8 0.1 0.066 11.5 0.1 1.1 1 0 0 1 1 1 0 Microtubule-associated protein Bicaudal-D CALCOCO1 PF07888.6 KLO12720.1 - 0.066 11.4 0.2 0.078 11.2 0.1 1.0 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like Laminin_II PF06009.7 KLO12720.1 - 0.11 12.2 0.7 0.15 11.8 0.5 1.2 1 0 0 1 1 1 0 Laminin Domain II CorA PF01544.13 KLO12720.1 - 0.13 11.3 1.1 0.15 11.0 0.7 1.1 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein PX PF00787.19 KLO12721.1 - 4.3e-14 52.2 0.1 7.9e-14 51.4 0.1 1.4 1 0 0 1 1 1 1 PX domain Glu_syn_central PF04898.9 KLO12721.1 - 0.11 11.7 0.0 0.2 10.9 0.0 1.3 1 0 0 1 1 1 0 Glutamate synthase central domain Methyltransf_23 PF13489.1 KLO12722.1 - 6e-26 91.0 0.0 9.3e-26 90.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KLO12722.1 - 9e-20 70.9 0.0 1.4e-19 70.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KLO12722.1 - 3.1e-15 56.4 0.0 5.8e-15 55.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KLO12722.1 - 3.4e-15 55.9 0.0 4.5e-15 55.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KLO12722.1 - 4.1e-14 53.1 0.0 6.4e-14 52.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KLO12722.1 - 3.8e-09 36.8 0.0 7e-09 35.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 KLO12722.1 - 4.8e-09 35.6 0.0 7e-09 35.1 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_26 PF13659.1 KLO12722.1 - 4.3e-07 29.9 0.0 1e-06 28.7 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 KLO12722.1 - 2.7e-06 26.7 0.0 3.9e-06 26.2 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_9 PF08003.6 KLO12722.1 - 5.7e-06 25.2 0.0 8.4e-06 24.6 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Ubie_methyltran PF01209.13 KLO12722.1 - 0.00042 19.4 0.0 0.00058 19.0 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.9 KLO12722.1 - 0.00045 19.6 0.0 0.00083 18.7 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase small domain NodS PF05401.6 KLO12722.1 - 0.00057 19.3 0.0 0.00081 18.8 0.0 1.2 1 0 0 1 1 1 1 Nodulation protein S (NodS) MetW PF07021.7 KLO12722.1 - 0.0027 17.1 0.1 0.0076 15.6 0.1 1.6 1 1 0 1 1 1 1 Methionine biosynthesis protein MetW DREV PF05219.7 KLO12722.1 - 0.017 14.0 0.0 0.026 13.3 0.0 1.2 1 0 0 1 1 1 0 DREV methyltransferase Methyltransf_32 PF13679.1 KLO12722.1 - 0.036 13.7 0.0 0.056 13.1 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain ERG4_ERG24 PF01222.12 KLO12723.1 - 1.7e-134 448.6 23.0 2e-134 448.4 16.0 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF1295 PF06966.7 KLO12723.1 - 4.3e-05 22.9 2.1 0.0001 21.6 1.4 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) Sec10 PF07393.6 KLO12724.1 - 1.7e-117 393.4 0.0 2.3e-112 376.5 0.0 2.3 2 1 0 2 2 2 2 Exocyst complex component Sec10 F-box-like PF12937.2 KLO12724.1 - 7.6e-05 22.3 0.1 0.00016 21.3 0.1 1.6 1 0 0 1 1 1 1 F-box-like Sporozoite_P67 PF05642.6 KLO12724.1 - 0.00027 18.9 1.2 0.00043 18.2 0.8 1.2 1 0 0 1 1 1 1 Sporozoite P67 surface antigen F-box PF00646.28 KLO12724.1 - 0.00048 19.6 0.0 0.0011 18.5 0.0 1.6 1 0 0 1 1 1 1 F-box domain NifU_N PF01592.11 KLO12724.1 - 0.041 13.8 0.0 0.11 12.3 0.0 1.7 1 0 0 1 1 1 0 NifU-like N terminal domain DUF4233 PF14017.1 KLO12726.1 - 0.037 13.9 2.4 0.51 10.2 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF4233) Aldedh PF00171.17 KLO12727.1 - 7.3e-14 50.9 2.3 3.4e-11 42.1 0.4 2.3 1 1 1 2 2 2 2 Aldehyde dehydrogenase family SHNi-TPR PF10516.4 KLO12728.1 - 2.9e-18 64.8 0.1 1e-15 56.6 0.0 2.8 2 0 0 2 2 2 1 SHNi-TPR TPR_11 PF13414.1 KLO12728.1 - 6.1e-14 51.4 0.5 5e-06 26.0 0.0 2.5 2 0 0 2 2 2 2 TPR repeat TPR_12 PF13424.1 KLO12728.1 - 8.4e-13 48.0 2.1 1.4e-06 28.0 0.0 2.8 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.23 KLO12728.1 - 2.6e-07 29.9 0.1 0.41 10.3 0.1 3.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.12 KLO12728.1 - 5.1e-06 26.0 1.9 0.28 11.1 0.2 4.2 4 1 0 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.1 KLO12728.1 - 2.1e-05 25.0 4.5 0.0043 17.6 0.8 3.5 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.1 KLO12728.1 - 0.0012 18.4 4.4 0.95 9.4 0.1 4.2 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.1 KLO12728.1 - 0.013 15.8 6.8 0.39 11.0 0.1 3.6 2 1 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.1 KLO12728.1 - 0.034 14.7 4.1 16 6.4 0.2 4.1 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.1 KLO12728.1 - 0.049 13.4 0.1 1.4 8.8 0.0 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat FliL PF03748.9 KLO12728.1 - 0.072 13.0 0.3 0.25 11.3 0.2 2.0 1 1 0 1 1 1 0 Flagellar basal body-associated protein FliL WXG100 PF06013.7 KLO12728.1 - 0.078 12.9 2.2 0.13 12.2 0.0 2.4 3 0 0 3 3 3 0 Proteins of 100 residues with WXG Prefoldin_2 PF01920.15 KLO12728.1 - 0.1 12.3 4.2 15 5.3 0.0 3.4 3 0 0 3 3 3 0 Prefoldin subunit TMF_DNA_bd PF12329.3 KLO12728.1 - 0.13 12.1 6.3 2.1 8.1 0.7 2.9 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding AATF-Che1 PF13339.1 KLO12728.1 - 9.8 6.3 10.9 0.34 11.0 0.8 3.1 2 1 1 4 4 4 0 Apoptosis antagonizing transcription factor ANTH PF07651.11 KLO12729.1 - 7e-52 175.8 0.1 9.6e-52 175.4 0.1 1.2 1 0 0 1 1 1 1 ANTH domain ENTH PF01417.15 KLO12729.1 - 2.7e-05 24.0 0.0 5e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 ENTH domain DUF1720 PF08226.6 KLO12729.1 - 3.8e-05 23.6 8.2 3.8e-05 23.6 5.7 6.3 3 1 2 5 5 5 4 Domain of unknown function (DUF1720) WD40 PF00400.27 KLO12730.1 - 3e-26 90.2 12.9 1.4e-07 31.0 0.0 6.9 7 0 0 7 7 7 5 WD domain, G-beta repeat eIF2A PF08662.6 KLO12730.1 - 0.0035 17.0 0.1 10 5.7 0.1 3.1 1 1 1 3 3 3 3 Eukaryotic translation initiation factor eIF2A Thymidylat_synt PF00303.14 KLO12731.1 - 2.8e-107 357.7 0.0 3.2e-107 357.5 0.0 1.0 1 0 0 1 1 1 1 Thymidylate synthase JmjC PF02373.17 KLO12732.1 - 2e-08 34.4 0.8 2e-08 34.4 0.5 2.8 2 1 0 2 2 2 1 JmjC domain, hydroxylase PHD PF00628.24 KLO12732.1 - 8.8e-07 28.5 7.8 8.8e-07 28.5 5.4 2.1 2 0 0 2 2 2 1 PHD-finger Cupin_8 PF13621.1 KLO12732.1 - 1.1e-05 25.0 2.8 6.5e-05 22.5 0.1 2.6 2 1 0 2 2 2 1 Cupin-like domain PHD_2 PF13831.1 KLO12732.1 - 0.0053 16.0 5.5 0.011 15.0 3.8 1.6 1 0 0 1 1 1 1 PHD-finger Prok-RING_1 PF14446.1 KLO12732.1 - 0.052 13.2 4.5 0.11 12.2 3.2 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 zf-CW PF07496.10 KLO12732.1 - 0.68 9.6 9.0 0.97 9.1 5.3 2.0 2 0 0 2 2 2 0 CW-type Zinc Finger Pea-VEAacid PF08111.6 KLO12733.1 - 0.045 13.8 0.4 0.77 9.9 0.0 2.9 2 0 0 2 2 2 0 Pea-VEAacid family Paf1 PF03985.8 KLO12734.1 - 7.4e-63 212.8 0.2 9e-63 212.5 0.2 1.0 1 0 0 1 1 1 1 Paf1 CRAL_TRIO PF00650.15 KLO12735.1 - 2.6e-29 101.7 0.0 3.5e-29 101.3 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 KLO12735.1 - 8.3e-07 29.0 0.0 2.7e-06 27.4 0.0 2.0 1 1 0 1 1 1 1 CRAL/TRIO, N-terminal domain Methyltransf_15 PF09445.5 KLO12737.1 - 5.5e-35 120.3 0.0 1.1e-25 90.1 0.0 2.1 2 0 0 2 2 2 2 RNA cap guanine-N2 methyltransferase Methyltransf_26 PF13659.1 KLO12737.1 - 2.7e-09 37.0 0.0 7.6e-09 35.6 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 KLO12737.1 - 2.5e-07 31.2 0.0 4.5e-07 30.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KLO12737.1 - 0.00018 21.7 0.0 0.00034 20.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Met_10 PF02475.11 KLO12737.1 - 0.00024 20.7 0.0 0.00045 19.8 0.0 1.3 1 0 0 1 1 1 1 Met-10+ like-protein Cons_hypoth95 PF03602.10 KLO12737.1 - 0.00046 19.6 0.0 0.00075 18.9 0.0 1.2 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_31 PF13847.1 KLO12737.1 - 0.00096 18.7 0.0 0.0015 18.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain UPF0020 PF01170.13 KLO12737.1 - 0.0013 18.2 0.0 0.0023 17.5 0.0 1.3 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_11 PF08241.7 KLO12737.1 - 0.014 15.9 0.0 0.052 14.0 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase domain PrmA PF06325.8 KLO12737.1 - 0.042 12.9 0.0 0.064 12.3 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) DNA_pol3_theta PF06440.6 KLO12737.1 - 0.15 11.6 0.2 0.35 10.4 0.1 1.6 1 0 0 1 1 1 0 DNA polymerase III, theta subunit ADH_zinc_N PF00107.21 KLO12737.1 - 0.16 11.4 0.0 0.27 10.7 0.0 1.4 1 0 0 1 1 1 0 Zinc-binding dehydrogenase THOC7 PF05615.8 KLO12740.1 - 2.6e-22 79.5 3.6 4.7e-22 78.7 2.5 1.4 1 0 0 1 1 1 1 Tho complex subunit 7 Luteo_P1-P2 PF08467.5 KLO12740.1 - 0.0034 16.2 0.5 0.0052 15.6 0.4 1.3 1 0 0 1 1 1 1 Luteovirus RNA polymerase P1-P2/replicase AAA_13 PF13166.1 KLO12740.1 - 0.079 11.4 5.2 0.12 10.8 3.6 1.2 1 0 0 1 1 1 0 AAA domain Lactamase_B_2 PF12706.2 KLO12741.1 - 3.2e-20 72.5 0.1 5.3e-20 71.7 0.1 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 KLO12741.1 - 3.5e-09 36.5 0.2 8.5e-09 35.3 0.1 1.8 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_4 PF13691.1 KLO12741.1 - 2.9e-05 23.4 0.0 5.5e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 tRNase Z endonuclease DnaJ PF00226.26 KLO12743.1 - 4.4e-11 42.3 0.1 1.3e-10 40.8 0.1 1.8 1 0 0 1 1 1 1 DnaJ domain DUF1767 PF08585.7 KLO12744.1 - 3.1e-12 46.6 0.3 9.6e-11 41.8 0.0 2.1 1 1 1 2 2 2 2 Domain of unknown function (DUF1767) Peptidase_M24 PF00557.19 KLO12745.1 - 3.6e-27 95.3 0.2 5.1e-27 94.8 0.1 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 TyeA PF09059.5 KLO12745.1 - 0.012 15.5 0.1 2.4 8.1 0.0 2.3 2 0 0 2 2 2 0 TyeA Pcc1 PF09341.5 KLO12746.1 - 2.7e-22 78.5 0.3 3e-22 78.4 0.2 1.0 1 0 0 1 1 1 1 Transcription factor Pcc1 MIF4G PF02854.14 KLO12747.1 - 2.3e-28 99.0 0.1 1.9e-27 96.0 0.0 2.1 2 0 0 2 2 2 1 MIF4G domain MA3 PF02847.12 KLO12747.1 - 1.5e-22 79.4 0.2 2.7e-20 72.1 0.0 2.6 2 0 0 2 2 2 2 MA3 domain Methyltransf_18 PF12847.2 KLO12748.1 - 2.6e-13 50.5 0.0 3.8e-13 50.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KLO12748.1 - 1.7e-12 47.1 0.0 2e-11 43.7 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KLO12748.1 - 9e-07 28.9 0.0 1.5e-06 28.2 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KLO12748.1 - 4.6e-06 26.1 0.0 7.1e-06 25.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_23 PF13489.1 KLO12748.1 - 8.6e-06 25.5 0.0 1.5e-05 24.7 0.0 1.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KLO12748.1 - 1.8e-05 25.1 0.0 3.2e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.1 KLO12748.1 - 1.9e-05 24.3 0.0 2.7e-05 23.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KLO12748.1 - 5.5e-05 23.4 0.0 8.7e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KLO12748.1 - 0.00024 21.5 0.0 0.0005 20.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_9 PF08003.6 KLO12748.1 - 0.00095 17.9 0.0 0.0013 17.5 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) TehB PF03848.9 KLO12748.1 - 0.005 16.0 0.0 0.0086 15.2 0.0 1.3 1 0 0 1 1 1 1 Tellurite resistance protein TehB PCMT PF01135.14 KLO12748.1 - 0.0096 15.4 0.0 0.014 14.8 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) DOT1 PF08123.8 KLO12748.1 - 0.01 15.1 0.0 0.015 14.6 0.0 1.2 1 0 0 1 1 1 0 Histone methylation protein DOT1 PrmA PF06325.8 KLO12748.1 - 0.032 13.3 0.0 0.043 12.9 0.0 1.1 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) tRNA_U5-meth_tr PF05958.6 KLO12748.1 - 0.047 12.3 0.0 0.063 11.9 0.0 1.1 1 0 0 1 1 1 0 tRNA (Uracil-5-)-methyltransferase Ubie_methyltran PF01209.13 KLO12748.1 - 0.061 12.4 0.0 0.087 11.9 0.0 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_4 PF02390.12 KLO12748.1 - 0.078 12.0 0.0 0.1 11.6 0.0 1.2 1 0 0 1 1 1 0 Putative methyltransferase MetW PF07021.7 KLO12748.1 - 0.12 11.6 0.0 0.18 11.1 0.0 1.2 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW N2227 PF07942.7 KLO12748.1 - 0.13 11.1 0.0 0.19 10.6 0.0 1.2 1 0 0 1 1 1 0 N2227-like protein Citrate_synt PF00285.16 KLO12750.1 - 5.8e-115 383.8 0.0 6.9e-115 383.5 0.0 1.1 1 0 0 1 1 1 1 Citrate synthase APH PF01636.18 KLO12751.1 - 1.1e-05 25.3 0.0 1.5e-05 24.8 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family CtaG_Cox11 PF04442.9 KLO12752.1 - 8.1e-53 178.2 0.1 1.6e-52 177.3 0.0 1.5 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein CtaG/Cox11 Nucleoplasmin PF03066.10 KLO12752.1 - 0.2 11.1 9.0 0.42 10.1 6.2 1.4 1 0 0 1 1 1 0 Nucleoplasmin CENP-B_dimeris PF09026.5 KLO12752.1 - 7 6.9 18.2 16 5.8 12.6 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain SNARE_assoc PF09335.6 KLO12753.1 - 4.7e-11 42.9 8.4 4.7e-11 42.9 5.8 2.4 3 0 0 3 3 3 1 SNARE associated Golgi protein Enhancin PF03272.8 KLO12754.1 - 0.045 11.6 0.1 0.06 11.2 0.0 1.1 1 0 0 1 1 1 0 Viral enhancin protein ARID PF01388.16 KLO12755.1 - 4.5e-11 42.4 0.0 1.6e-10 40.7 0.0 2.0 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain EST1 PF10374.4 KLO12755.1 - 0.046 13.7 0.0 0.25 11.3 0.0 2.3 1 0 0 1 1 1 0 Telomerase activating protein Est1 Exo_endo_phos PF03372.18 KLO12756.1 - 8.3e-13 48.8 0.1 6.2e-09 36.1 0.0 2.4 2 0 0 2 2 2 2 Endonuclease/Exonuclease/phosphatase family Herpes_DNAp_acc PF04929.7 KLO12756.1 - 1.9 7.3 4.9 0.32 9.8 0.1 2.1 2 0 0 2 2 2 0 Herpes DNA replication accessory factor DUF843 PF05814.6 KLO12757.1 - 0.93 9.3 3.9 2.6 7.9 0.0 2.8 3 0 0 3 3 3 0 Baculovirus protein of unknown function (DUF843) SSP160 PF06933.6 KLO12758.1 - 0.096 10.6 2.2 0.1 10.5 1.5 1.0 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 zf-C3HC4_3 PF13920.1 KLO12762.1 - 5.7e-08 32.3 9.5 1.3e-07 31.1 6.6 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KLO12762.1 - 5.7e-05 22.8 10.8 5.7e-05 22.8 7.5 2.4 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4 PF00097.20 KLO12762.1 - 0.00029 20.4 11.4 0.00066 19.2 7.9 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KLO12762.1 - 0.00066 19.6 12.9 0.00066 19.6 9.0 2.6 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KLO12762.1 - 0.0013 18.4 10.7 0.0041 16.8 7.4 1.9 1 0 0 1 1 1 1 zinc-RING finger domain zf-CCCH PF00642.19 KLO12762.1 - 0.0016 18.0 3.7 0.0016 18.0 2.6 3.6 3 0 0 3 3 3 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) HMGL-like PF00682.14 KLO12763.1 - 7.7e-70 235.2 0.5 1.3e-69 234.4 0.3 1.4 1 0 0 1 1 1 1 HMGL-like MerR-DNA-bind PF09278.6 KLO12763.1 - 0.48 10.8 2.7 0.46 10.9 0.2 2.1 1 1 1 2 2 2 0 MerR, DNA binding RNase_T PF00929.19 KLO12764.1 - 0.00032 21.0 0.0 0.00056 20.2 0.0 1.4 1 0 0 1 1 1 1 Exonuclease RNase_T PF00929.19 KLO12765.1 - 0.023 14.9 0.0 0.036 14.3 0.0 1.3 1 0 0 1 1 1 0 Exonuclease MOZ_SAS PF01853.13 KLO12768.1 - 1.2e-71 239.8 0.1 1.7e-71 239.4 0.0 1.1 1 0 0 1 1 1 1 MOZ/SAS family PHD PF00628.24 KLO12769.1 - 2.9e-05 23.6 8.2 2.9e-05 23.6 5.7 2.0 1 1 1 2 2 2 1 PHD-finger zf-CCHC PF00098.18 KLO12769.1 - 0.048 13.6 0.6 0.048 13.6 0.4 2.8 3 1 0 3 3 3 0 Zinc knuckle Fer4_2 PF12797.2 KLO12769.1 - 1.7 8.6 12.6 0.23 11.4 1.8 2.7 2 1 0 2 2 2 0 4Fe-4S binding domain C1_1 PF00130.17 KLO12769.1 - 3.4 7.4 12.2 0.53 10.0 0.5 2.5 1 1 1 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-nanos PF05741.8 KLO12769.1 - 6.2 6.8 9.6 3.5e+02 1.2 6.6 2.8 1 1 1 2 2 2 0 Nanos RNA binding domain DUF116 PF01976.12 KLO12769.1 - 6.5 6.2 10.1 0.36 10.2 3.5 1.4 2 0 0 2 2 2 0 Protein of unknown function DUF116 Pkinase PF00069.20 KLO12770.1 - 2.8e-40 138.1 0.0 3.7e-40 137.7 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KLO12770.1 - 1e-39 136.1 0.0 1.3e-39 135.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KLO12770.1 - 0.00011 21.2 0.0 0.0002 20.4 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 KLO12770.1 - 0.012 15.4 0.0 0.018 14.7 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family RIO1 PF01163.17 KLO12770.1 - 0.083 12.2 0.0 0.18 11.1 0.0 1.5 1 0 0 1 1 1 0 RIO1 family Pkinase_Tyr PF07714.12 KLO12771.1 - 1.3e-11 44.0 0.0 1.8e-11 43.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 KLO12771.1 - 1.7e-11 43.7 0.0 2.2e-11 43.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase PF00069.20 KLO12774.1 - 7.3e-55 185.9 0.0 1e-54 185.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KLO12774.1 - 1e-17 64.0 0.0 1.7e-17 63.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.17 KLO12774.1 - 0.053 12.8 0.2 0.17 11.2 0.1 1.8 1 1 1 2 2 2 0 RIO1 family APH PF01636.18 KLO12774.1 - 0.096 12.3 0.9 0.56 9.8 0.4 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family MCPVI PF02993.9 KLO12774.1 - 0.43 10.6 3.1 0.89 9.6 2.2 1.5 1 0 0 1 1 1 0 Minor capsid protein VI DUF2803 PF10972.3 KLO12779.1 - 0.022 14.2 0.1 0.042 13.3 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2803) DUF2963 PF11178.3 KLO12780.1 - 0.39 10.1 5.1 4.4 6.7 0.3 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2963) HSP70 PF00012.15 KLO12783.1 - 0.031 12.2 0.0 0.2 9.5 0.0 2.0 2 1 0 2 2 2 0 Hsp70 protein Troponin PF00992.15 KLO12784.1 - 0.24 11.4 7.0 1.2 9.1 0.9 2.5 2 0 0 2 2 2 0 Troponin HSP70 PF00012.15 KLO12785.1 - 0.09 10.6 0.0 6.2 4.6 0.0 2.4 2 1 0 2 2 2 0 Hsp70 protein Hydantoinase_A PF01968.13 KLO12785.1 - 0.16 11.0 0.0 1.4 7.9 0.0 2.1 2 0 0 2 2 2 0 Hydantoinase/oxoprolinase Transposase_21 PF02992.9 KLO12793.1 - 0.11 11.6 1.5 0.13 11.3 0.0 1.9 2 0 0 2 2 2 0 Transposase family tnp2 Transposase_21 PF02992.9 KLO12794.1 - 1.1e-07 31.1 0.0 1.7e-07 30.6 0.0 1.2 1 0 0 1 1 1 1 Transposase family tnp2 DUF4218 PF13960.1 KLO12795.1 - 7.6e-07 28.6 0.0 7.7e-07 28.5 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4218) Asp PF00026.18 KLO12797.1 - 4.7e-65 219.9 7.5 6e-65 219.5 5.2 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 KLO12797.1 - 2.3e-06 27.6 0.8 4.7e-06 26.6 0.5 1.6 1 0 0 1 1 1 1 Xylanase inhibitor N-terminal CS PF04969.11 KLO12799.1 - 6.4e-09 36.2 0.0 1.1e-08 35.4 0.0 1.4 1 0 0 1 1 1 1 CS domain MAS20 PF02064.10 KLO12799.1 - 0.017 15.0 0.1 7.6 6.4 0.0 3.2 3 0 0 3 3 3 0 MAS20 protein import receptor TPR_2 PF07719.12 KLO12799.1 - 0.042 13.7 0.9 0.15 12.0 0.1 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat Pkinase PF00069.20 KLO12801.1 - 2.2e-63 213.8 0.0 4.5e-41 140.7 0.0 2.8 3 0 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.12 KLO12801.1 - 6.8e-28 97.4 0.0 4.6e-23 81.6 0.0 2.4 2 0 0 2 2 2 2 Protein tyrosine kinase Response_reg PF00072.19 KLO12801.1 - 6.6e-14 51.8 0.0 1.6e-13 50.6 0.0 1.7 1 0 0 1 1 1 1 Response regulator receiver domain Kinase-like PF14531.1 KLO12801.1 - 1.1e-07 31.1 0.0 5.3e-05 22.3 0.0 2.4 1 1 0 2 2 2 2 Kinase-like APH PF01636.18 KLO12801.1 - 0.0025 17.5 0.1 0.0025 17.5 0.1 2.4 2 1 1 3 3 3 1 Phosphotransferase enzyme family PAS_9 PF13426.1 KLO12801.1 - 0.0037 17.6 0.0 0.014 15.7 0.0 2.0 1 0 0 1 1 1 1 PAS domain Kdo PF06293.9 KLO12801.1 - 0.0098 14.9 0.0 0.028 13.4 0.0 1.7 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.6 KLO12801.1 - 0.019 13.7 0.0 0.034 12.9 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 RIO1 PF01163.17 KLO12801.1 - 0.031 13.6 0.1 0.076 12.3 0.1 1.6 1 0 0 1 1 1 0 RIO1 family IFT46_B_C PF12317.3 KLO12801.1 - 0.21 10.9 1.3 0.4 10.0 0.9 1.4 1 0 0 1 1 1 0 Intraflagellar transport complex B protein 46 C terminal Abhydrolase_6 PF12697.2 KLO12802.1 - 3.4e-31 108.8 0.2 9.4e-31 107.4 0.1 1.8 2 1 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KLO12802.1 - 1.1e-18 67.3 0.0 6.3e-12 45.4 0.0 2.3 2 0 0 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KLO12802.1 - 1.9e-16 60.3 0.0 2.8e-12 46.6 0.0 2.3 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_3 PF07859.8 KLO12802.1 - 3.4e-05 23.5 0.0 0.0011 18.5 0.0 2.2 1 1 0 2 2 2 1 alpha/beta hydrolase fold Esterase PF00756.15 KLO12802.1 - 9.9e-05 21.8 0.1 0.0002 20.8 0.1 1.6 1 1 0 1 1 1 1 Putative esterase BAAT_C PF08840.6 KLO12802.1 - 0.00069 19.3 0.0 0.24 11.0 0.0 2.2 2 0 0 2 2 2 2 BAAT / Acyl-CoA thioester hydrolase C terminal Hydrolase_4 PF12146.3 KLO12802.1 - 0.0027 17.5 0.0 0.0075 16.1 0.0 1.7 1 0 0 1 1 1 1 Putative lysophospholipase Ndr PF03096.9 KLO12802.1 - 0.0029 16.1 0.0 0.0051 15.3 0.0 1.3 1 0 0 1 1 1 1 Ndr family DUF2305 PF10230.4 KLO12802.1 - 0.003 17.0 0.0 0.0054 16.1 0.0 1.4 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2305) Ser_hydrolase PF06821.8 KLO12802.1 - 0.0056 16.3 0.0 0.011 15.3 0.0 1.5 1 0 0 1 1 1 1 Serine hydrolase Lipase_3 PF01764.20 KLO12802.1 - 0.014 15.0 0.0 0.024 14.2 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) Abhydrolase_4 PF08386.5 KLO12802.1 - 0.05 13.4 0.0 0.11 12.3 0.0 1.6 1 0 0 1 1 1 0 TAP-like protein DUF915 PF06028.6 KLO12802.1 - 0.081 11.9 0.0 0.23 10.5 0.0 1.8 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) Pkinase_Tyr PF07714.12 KLO12803.1 - 2e-46 158.1 0.0 2.9e-46 157.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 KLO12803.1 - 1.2e-40 139.3 0.0 2.1e-40 138.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.18 KLO12803.1 - 0.0054 16.4 0.3 0.02 14.6 0.0 2.0 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.9 KLO12803.1 - 0.026 13.5 0.0 0.045 12.8 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family TPR_12 PF13424.1 KLO12803.1 - 0.032 14.1 0.1 0.14 12.0 0.0 2.1 1 1 1 2 2 2 0 Tetratricopeptide repeat RIO1 PF01163.17 KLO12803.1 - 0.095 12.0 0.1 0.19 11.0 0.0 1.4 1 0 0 1 1 1 0 RIO1 family Fork_head PF00250.13 KLO12804.1 - 6e-21 74.2 0.3 1.4e-20 73.1 0.0 1.6 2 0 0 2 2 2 1 Fork head domain FHA PF00498.21 KLO12804.1 - 2.3e-07 30.8 0.0 3.7e-07 30.1 0.0 1.4 1 0 0 1 1 1 1 FHA domain MT-A70 PF05063.9 KLO12805.1 - 5e-56 189.0 0.0 6.5e-56 188.6 0.0 1.2 1 0 0 1 1 1 1 MT-A70 DUF572 PF04502.8 KLO12806.1 - 5.6 6.0 10.9 8.3 5.5 7.6 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) adh_short PF00106.20 KLO12807.1 - 2.4e-09 37.3 0.0 3.7e-09 36.7 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KLO12807.1 - 5e-05 23.0 0.0 6.5e-05 22.6 0.0 1.2 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 KLO12807.1 - 0.014 15.2 0.0 0.021 14.5 0.0 1.4 1 1 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase CsbD PF05532.7 KLO12808.1 - 0.14 11.8 0.1 0.34 10.6 0.0 1.6 2 0 0 2 2 2 0 CsbD-like AAA PF00004.24 KLO12810.1 - 2e-32 112.1 0.0 3.5e-32 111.3 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 KLO12810.1 - 5.3e-09 36.2 0.1 7.1e-08 32.6 0.0 2.4 2 1 0 2 2 2 1 AAA domain AAA_17 PF13207.1 KLO12810.1 - 4.2e-07 30.8 0.1 2e-06 28.6 0.1 2.2 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 KLO12810.1 - 3e-06 27.1 0.0 1.2e-05 25.1 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 KLO12810.1 - 4.5e-06 26.7 0.1 1.3e-05 25.3 0.1 1.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_18 PF13238.1 KLO12810.1 - 9.7e-06 25.9 0.0 1.9e-05 24.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.1 KLO12810.1 - 1.4e-05 25.0 0.0 2.6e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_2 PF07724.9 KLO12810.1 - 1.9e-05 24.6 0.0 3.9e-05 23.6 0.0 1.5 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_28 PF13521.1 KLO12810.1 - 2.7e-05 24.2 0.0 5.2e-05 23.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain Arch_ATPase PF01637.13 KLO12810.1 - 0.00028 20.6 0.2 0.02 14.6 0.1 2.2 1 1 0 1 1 1 1 Archaeal ATPase AAA_5 PF07728.9 KLO12810.1 - 0.0003 20.5 0.0 0.00062 19.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_19 PF13245.1 KLO12810.1 - 0.00035 20.2 0.0 0.0014 18.3 0.0 2.0 2 0 0 2 2 1 1 Part of AAA domain RuvB_N PF05496.7 KLO12810.1 - 0.00061 18.8 0.4 0.0041 16.2 0.3 2.1 1 1 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus UPF0079 PF02367.12 KLO12810.1 - 0.00064 19.3 0.0 0.0013 18.3 0.0 1.4 1 0 0 1 1 1 1 Uncharacterised P-loop hydrolase UPF0079 AAA_11 PF13086.1 KLO12810.1 - 0.0007 19.2 0.0 0.0013 18.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain NACHT PF05729.7 KLO12810.1 - 0.001 18.7 0.1 0.0035 17.0 0.1 1.9 1 1 0 1 1 1 1 NACHT domain RNA_helicase PF00910.17 KLO12810.1 - 0.0011 19.0 0.0 0.0028 17.8 0.0 1.7 1 0 0 1 1 1 1 RNA helicase AAA_25 PF13481.1 KLO12810.1 - 0.0011 18.3 0.1 0.078 12.3 0.0 2.2 1 1 1 2 2 2 1 AAA domain Viral_helicase1 PF01443.13 KLO12810.1 - 0.0012 18.4 0.0 0.0021 17.6 0.0 1.4 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase TIP49 PF06068.8 KLO12810.1 - 0.0014 17.4 0.0 0.002 16.9 0.0 1.2 1 0 0 1 1 1 1 TIP49 C-terminus PduV-EutP PF10662.4 KLO12810.1 - 0.0033 16.9 0.0 0.0059 16.0 0.0 1.4 1 0 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation AAA_24 PF13479.1 KLO12810.1 - 0.0036 16.9 0.0 0.0075 15.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.12 KLO12810.1 - 0.0049 16.3 0.0 0.012 15.0 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein Rad17 PF03215.10 KLO12810.1 - 0.008 14.9 0.0 0.034 12.8 0.0 1.8 2 0 0 2 2 2 1 Rad17 cell cycle checkpoint protein DUF815 PF05673.8 KLO12810.1 - 0.012 14.5 0.0 0.17 10.8 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_30 PF13604.1 KLO12810.1 - 0.022 14.3 0.0 0.05 13.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.7 KLO12810.1 - 0.029 13.4 0.0 0.055 12.5 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin DUF2075 PF09848.4 KLO12810.1 - 0.034 13.1 0.0 0.051 12.5 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) KAP_NTPase PF07693.9 KLO12810.1 - 0.038 12.9 0.0 0.29 10.0 0.0 2.2 2 1 0 2 2 2 0 KAP family P-loop domain ABC_tran PF00005.22 KLO12810.1 - 0.039 14.2 0.0 0.076 13.3 0.0 1.5 1 0 0 1 1 1 0 ABC transporter Mg_chelatase PF01078.16 KLO12810.1 - 0.059 12.5 0.0 0.14 11.2 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI MobB PF03205.9 KLO12810.1 - 0.06 13.0 0.0 0.15 11.7 0.0 1.7 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_3 PF07726.6 KLO12810.1 - 0.078 12.5 0.0 0.17 11.5 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) CPT PF07931.7 KLO12810.1 - 0.098 12.2 0.0 0.18 11.4 0.0 1.4 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein FtsK_SpoIIIE PF01580.13 KLO12810.1 - 0.11 11.9 0.2 4 6.8 0.0 2.9 3 0 0 3 3 3 0 FtsK/SpoIIIE family AAA_23 PF13476.1 KLO12810.1 - 0.11 12.7 0.0 0.2 11.9 0.0 1.4 1 1 0 1 1 1 0 AAA domain Sigma54_activat PF00158.21 KLO12810.1 - 0.13 11.7 0.0 0.25 10.7 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain PhoH PF02562.11 KLO12810.1 - 0.13 11.4 0.0 0.36 10.0 0.0 1.6 2 0 0 2 2 2 0 PhoH-like protein DUF258 PF03193.11 KLO12810.1 - 0.14 11.3 0.0 0.41 9.8 0.0 1.7 2 0 0 2 2 1 0 Protein of unknown function, DUF258 PPR_3 PF13812.1 KLO12811.1 - 0.027 14.7 0.5 0.37 11.1 0.0 3.3 4 0 0 4 4 4 0 Pentatricopeptide repeat domain PPR_2 PF13041.1 KLO12811.1 - 0.11 12.4 2.1 5.4 7.0 0.0 3.0 3 0 0 3 3 3 0 PPR repeat family TPMT PF05724.6 KLO12812.1 - 7.2e-35 120.4 0.0 8.8e-35 120.1 0.0 1.1 1 0 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) Methyltransf_11 PF08241.7 KLO12812.1 - 2e-08 34.6 0.0 3e-08 34.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KLO12812.1 - 2.2e-08 33.8 0.0 3.1e-08 33.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KLO12812.1 - 7.8e-08 32.3 0.0 1.6e-07 31.3 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KLO12812.1 - 1.7e-07 31.0 0.0 2.5e-07 30.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KLO12812.1 - 1.2e-06 28.9 0.0 1.9e-06 28.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KLO12812.1 - 1.2e-06 29.0 0.0 3.7e-06 27.4 0.0 1.8 2 1 0 2 2 2 1 Methyltransferase domain TehB PF03848.9 KLO12812.1 - 3.7e-06 26.2 0.0 4.6e-06 25.9 0.0 1.1 1 0 0 1 1 1 1 Tellurite resistance protein TehB MTS PF05175.9 KLO12812.1 - 0.021 14.2 0.0 0.033 13.5 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase small domain N2227 PF07942.7 KLO12812.1 - 0.048 12.6 0.1 4.3 6.2 0.0 2.1 1 1 1 2 2 2 0 N2227-like protein TPMT PF05724.6 KLO12813.1 - 3.8e-41 140.9 0.0 4.7e-41 140.6 0.0 1.1 1 0 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) Methyltransf_31 PF13847.1 KLO12813.1 - 8.9e-10 38.3 0.0 1.5e-09 37.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KLO12813.1 - 2.8e-08 34.3 0.0 6.1e-08 33.2 0.0 1.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 KLO12813.1 - 3.6e-08 33.7 0.0 7.2e-08 32.8 0.0 1.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 KLO12813.1 - 1.1e-06 28.6 0.0 2e-06 27.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KLO12813.1 - 7.2e-06 26.4 0.0 1.1e-05 25.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KLO12813.1 - 1.3e-05 25.0 0.0 1.7e-05 24.5 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KLO12813.1 - 6.3e-05 23.2 0.0 9.3e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain TehB PF03848.9 KLO12813.1 - 0.0024 17.0 0.0 0.0039 16.3 0.0 1.4 1 0 0 1 1 1 1 Tellurite resistance protein TehB MTS PF05175.9 KLO12813.1 - 0.0051 16.2 0.0 0.0081 15.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain PCMT PF01135.14 KLO12813.1 - 0.083 12.4 0.0 0.11 12.0 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) CMAS PF02353.15 KLO12813.1 - 0.089 11.8 0.0 0.13 11.3 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase N2227 PF07942.7 KLO12813.1 - 0.16 10.8 0.2 1.8 7.4 0.0 2.0 1 1 1 2 2 2 0 N2227-like protein HSF_DNA-bind PF00447.12 KLO12816.1 - 2.1e-13 50.3 0.0 3.1e-13 49.7 0.0 1.3 1 0 0 1 1 1 1 HSF-type DNA-binding Pkinase PF00069.20 KLO12817.1 - 6e-70 235.3 0.0 8.5e-70 234.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KLO12817.1 - 5.1e-30 104.3 0.0 9.8e-29 100.2 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KLO12817.1 - 1.4e-07 30.7 2.4 0.00054 19.0 0.1 3.3 3 1 0 3 3 3 2 Kinase-like APH PF01636.18 KLO12817.1 - 0.0093 15.7 0.0 0.63 9.7 0.0 2.5 2 1 1 3 3 3 1 Phosphotransferase enzyme family Kdo PF06293.9 KLO12817.1 - 0.014 14.4 0.0 0.024 13.6 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family F_actin_cap_B PF01115.12 KLO12817.1 - 0.1 11.7 0.1 0.21 10.7 0.0 1.4 1 1 0 1 1 1 0 F-actin capping protein, beta subunit SNARE_assoc PF09335.6 KLO12818.1 - 7.6e-13 48.7 9.6 7.6e-13 48.7 6.7 2.4 2 1 1 3 3 3 1 SNARE associated Golgi protein MerE PF05052.7 KLO12818.1 - 0.028 14.3 0.3 0.028 14.3 0.2 2.1 2 0 0 2 2 2 0 MerE protein SpoIIIAH PF12685.2 KLO12818.1 - 0.12 11.8 0.0 0.18 11.2 0.0 1.3 1 0 0 1 1 1 0 SpoIIIAH-like protein DUF3816 PF12822.2 KLO12818.1 - 0.16 11.8 5.2 0.34 10.7 3.6 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3816) PEX11 PF05648.9 KLO12820.1 - 2.7e-11 43.1 2.7 2.6e-05 23.5 0.3 2.8 2 1 0 2 2 2 2 Peroxisomal biogenesis factor 11 (PEX11) Tctex-1 PF03645.8 KLO12821.1 - 5.3e-09 35.8 0.1 7.6e-09 35.3 0.1 1.2 1 0 0 1 1 1 1 Tctex-1 family MFS_1 PF07690.11 KLO12822.1 - 4.2e-23 81.6 45.5 4.5e-18 65.0 8.3 3.4 1 1 2 3 3 3 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KLO12822.1 - 4.6e-08 32.0 9.0 4.6e-08 32.0 6.2 3.0 2 1 0 3 3 3 2 Sugar (and other) transporter TRI12 PF06609.8 KLO12822.1 - 2.4e-06 26.0 9.2 0.0021 16.3 0.7 2.4 1 1 1 2 2 2 2 Fungal trichothecene efflux pump (TRI12) MFS_2 PF13347.1 KLO12822.1 - 5.7e-05 21.6 17.6 0.0073 14.7 5.3 2.7 2 1 0 2 2 2 2 MFS/sugar transport protein Ribosomal_S14 PF00253.16 KLO12824.1 - 1.9e-18 65.6 0.1 2.7e-18 65.0 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein S14p/S29e DUF3425 PF11905.3 KLO12825.1 - 5.9e-17 61.8 0.8 8.2e-15 54.9 0.6 2.5 1 1 0 1 1 1 1 Domain of unknown function (DUF3425) bZIP_1 PF00170.16 KLO12825.1 - 4.2e-09 36.2 10.3 3.2e-08 33.3 7.1 2.2 1 1 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 KLO12825.1 - 0.0013 18.4 13.1 0.011 15.5 4.1 2.5 1 1 1 2 2 2 2 Basic region leucine zipper bZIP_Maf PF03131.12 KLO12825.1 - 0.79 10.0 7.9 0.17 12.2 3.0 1.7 2 0 0 2 2 2 0 bZIP Maf transcription factor DNA_RNApol_7kD PF03604.8 KLO12827.1 - 2.2e-16 58.9 4.4 3e-16 58.5 3.0 1.2 1 0 0 1 1 1 1 DNA directed RNA polymerase, 7 kDa subunit C1_1 PF00130.17 KLO12827.1 - 0.0087 15.7 0.2 0.016 14.9 0.2 1.4 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) HypA PF01155.14 KLO12827.1 - 0.017 14.7 0.2 0.021 14.4 0.1 1.2 1 0 0 1 1 1 0 Hydrogenase expression/synthesis hypA family Zn-ribbon_8 PF09723.5 KLO12827.1 - 0.04 13.8 2.9 0.097 12.6 2.0 1.7 1 1 0 1 1 1 0 Zinc ribbon domain OrfB_Zn_ribbon PF07282.6 KLO12827.1 - 0.044 13.4 0.6 0.062 12.9 0.4 1.3 1 0 0 1 1 1 0 Putative transposase DNA-binding domain zf-C3HC PF07967.8 KLO12827.1 - 0.057 13.1 0.1 0.069 12.9 0.0 1.1 1 0 0 1 1 1 0 C3HC zinc finger-like zf-ISL3 PF14690.1 KLO12827.1 - 0.063 13.3 3.6 0.1 12.6 0.7 2.1 2 0 0 2 2 2 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 DZR PF12773.2 KLO12827.1 - 0.07 12.9 4.0 0.15 11.8 2.8 1.8 1 1 0 1 1 1 0 Double zinc ribbon TFIIS_C PF01096.13 KLO12827.1 - 0.099 12.2 0.7 3.7 7.2 0.1 2.3 2 0 0 2 2 2 0 Transcription factor S-II (TFIIS) zf-ribbon_3 PF13248.1 KLO12827.1 - 0.11 11.7 2.2 8.5 5.7 0.3 2.6 2 1 0 2 2 2 0 zinc-ribbon domain A2L_zn_ribbon PF08792.5 KLO12827.1 - 0.21 11.0 1.7 4.5 6.8 0.0 2.8 3 0 0 3 3 3 0 A2L zinc ribbon domain zinc_ribbon_2 PF13240.1 KLO12827.1 - 0.27 10.7 0.2 0.27 10.7 0.1 2.1 2 1 0 2 2 1 0 zinc-ribbon domain Zn_ribbon_recom PF13408.1 KLO12827.1 - 0.29 11.4 4.3 0.88 9.8 0.5 2.2 2 0 0 2 2 2 0 Recombinase zinc beta ribbon domain Zn_Tnp_IS1595 PF12760.2 KLO12827.1 - 0.33 10.8 4.7 2 8.3 2.9 2.1 1 1 2 3 3 3 0 Transposase zinc-ribbon domain zf-HYPF PF07503.7 KLO12827.1 - 1 8.8 6.8 2.6 7.5 0.1 2.8 2 1 1 3 3 3 0 HypF finger Mu-like_Com PF10122.4 KLO12827.1 - 1.7 7.7 6.1 6.1 5.9 0.0 2.2 1 1 1 2 2 2 0 Mu-like prophage protein Com zf-trcl PF13451.1 KLO12827.1 - 2.1 8.0 6.4 5.6 6.6 0.9 2.2 1 1 1 2 2 2 0 Probable zinc-binding domain RRM_1 PF00076.17 KLO12829.1 - 4.4e-26 90.2 0.0 1.4e-13 50.2 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KLO12829.1 - 8e-23 80.2 0.3 1.5e-10 40.8 0.0 2.8 3 0 0 3 3 3 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) DUF4187 PF13821.1 KLO12829.1 - 2.3e-20 71.9 0.5 2.3e-20 71.9 0.4 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF4187) RRM_5 PF13893.1 KLO12829.1 - 2.3e-08 33.7 0.0 0.0059 16.4 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) G-patch PF01585.18 KLO12829.1 - 1e-05 25.1 4.0 1.4e-05 24.7 0.9 2.5 2 0 0 2 2 2 1 G-patch domain OB_RNB PF08206.6 KLO12829.1 - 0.092 12.2 1.4 3.3 7.2 0.0 3.2 3 0 0 3 3 3 0 Ribonuclease B OB domain LRR_4 PF12799.2 KLO12830.1 - 0.2 11.3 0.8 9.8 5.9 0.1 3.4 3 2 1 4 4 4 0 Leucine Rich repeats (2 copies) LRR_7 PF13504.1 KLO12830.1 - 0.59 10.5 3.2 24 5.6 0.3 4.3 5 0 0 5 5 5 0 Leucine rich repeat Glyco_hydro_cc PF11790.3 KLO12831.1 - 1.2e-57 195.0 0.4 1.7e-57 194.6 0.3 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core DUF4614 PF15391.1 KLO12831.1 - 0.033 13.9 8.9 0.052 13.3 6.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4614) DNA_pol_viral_N PF00242.12 KLO12831.1 - 9.2 5.1 9.3 13 4.7 6.5 1.1 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain Glyco_hydro_cc PF11790.3 KLO12832.1 - 6.8e-60 202.4 5.8 8.9e-60 202.0 4.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core Serglycin PF04360.7 KLO12832.1 - 0.03 14.0 1.3 0.072 12.8 0.9 1.6 1 0 0 1 1 1 0 Serglycin Ribosomal_L11 PF00298.14 KLO12836.1 - 1.2e-27 95.8 0.3 2.1e-27 95.0 0.2 1.4 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain Ribosomal_L11_N PF03946.9 KLO12836.1 - 1e-24 85.7 0.7 1.5e-24 85.1 0.2 1.6 2 0 0 2 2 2 1 Ribosomal protein L11, N-terminal domain Peptidase_M28 PF04389.12 KLO12837.1 - 7.6e-28 97.4 0.1 1.2e-27 96.8 0.1 1.3 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.23 KLO12837.1 - 1.7e-07 30.9 0.0 2.6e-07 30.3 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 WD40 PF00400.27 KLO12838.1 - 2.3e-05 24.0 3.9 0.0077 16.0 0.0 3.9 3 1 0 3 3 3 2 WD domain, G-beta repeat Ashwin PF15323.1 KLO12838.1 - 2.6 7.9 12.1 0.79 9.6 3.3 2.4 2 0 0 2 2 2 0 Developmental protein WD40 PF00400.27 KLO12840.1 - 8.9e-09 34.9 4.6 0.00089 19.0 1.3 3.5 3 0 0 3 3 3 3 WD domain, G-beta repeat DUF2373 PF10180.4 KLO12841.1 - 8.9e-15 53.9 0.5 2.9e-06 26.7 0.0 2.3 2 0 0 2 2 2 2 Uncharacterised conserved protein (DUF2373) Mitofilin PF09731.4 KLO12841.1 - 0.13 10.9 17.2 0.16 10.5 11.9 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein FAM60A PF15396.1 KLO12841.1 - 2.3 7.9 15.6 0.31 10.7 7.8 1.8 2 0 0 2 2 2 0 Protein Family FAM60A TATR PF03430.8 KLO12841.1 - 2.5 6.6 12.3 3.7 6.0 8.5 1.3 1 0 0 1 1 1 0 Trans-activating transcriptional regulator Arf PF00025.16 KLO12842.1 - 9.6e-69 230.0 0.0 1.2e-68 229.8 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.15 KLO12842.1 - 9.5e-12 44.2 0.2 1.1e-06 27.6 0.0 2.4 2 1 0 2 2 2 2 G-protein alpha subunit Ras PF00071.17 KLO12842.1 - 1.3e-11 44.1 0.0 1.5e-11 43.9 0.0 1.1 1 0 0 1 1 1 1 Ras family SRPRB PF09439.5 KLO12842.1 - 7.1e-10 38.3 0.0 8.9e-10 38.0 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.7 KLO12842.1 - 9e-09 34.8 0.0 1.1e-08 34.5 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 KLO12842.1 - 5.1e-08 33.4 0.0 7e-08 32.9 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 KLO12842.1 - 0.00028 20.8 0.0 0.00039 20.3 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase WD40 PF00400.27 KLO12843.1 - 1.4e-32 110.4 15.0 2.7e-11 42.8 0.9 5.7 6 0 0 6 6 6 5 WD domain, G-beta repeat IKI3 PF04762.7 KLO12843.1 - 0.057 11.2 0.0 0.086 10.6 0.0 1.2 1 0 0 1 1 1 0 IKI3 family Iso_dh PF00180.15 KLO12844.1 - 2.3e-97 326.0 0.0 2.6e-97 325.9 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase F-box-like PF12937.2 KLO12845.1 - 0.021 14.5 0.1 0.021 14.5 0.1 2.0 2 0 0 2 2 2 0 F-box-like Flavokinase PF01687.12 KLO12846.1 - 2e-35 121.4 0.0 2.4e-35 121.1 0.0 1.1 1 0 0 1 1 1 1 Riboflavin kinase RRM_1 PF00076.17 KLO12847.1 - 4.9e-13 48.5 0.0 6.2e-13 48.1 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KLO12847.1 - 4.9e-10 39.2 0.0 6.4e-10 38.8 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KLO12847.1 - 0.019 14.7 0.0 0.027 14.3 0.0 1.3 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) cwf21 PF08312.7 KLO12848.1 - 7.8e-14 51.2 12.7 7.8e-14 51.2 8.8 2.6 3 0 0 3 3 3 1 cwf21 domain Ycf1 PF05758.7 KLO12848.1 - 0.047 11.4 3.4 0.051 11.2 2.3 1.2 1 0 0 1 1 1 0 Ycf1 Aminotran_1_2 PF00155.16 KLO12849.1 - 1.9e-76 257.3 0.0 2.5e-76 256.9 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.14 KLO12849.1 - 1.3e-05 24.1 0.0 2.3e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.15 KLO12849.1 - 0.00012 20.4 0.0 0.00021 19.7 0.0 1.3 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Pertussis_S1 PF02917.9 KLO12849.1 - 0.022 14.3 0.1 0.072 12.6 0.0 1.9 2 0 0 2 2 2 0 Pertussis toxin, subunit 1 Aminotran_3 PF00202.16 KLO12850.1 - 3.3e-85 285.9 0.0 4.6e-85 285.4 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.16 KLO12850.1 - 0.0079 15.1 0.0 0.017 14.0 0.0 1.5 2 0 0 2 2 2 1 Aminotransferase class I and II DUF1237 PF06824.6 KLO12852.1 - 7.2e-128 426.7 0.1 9.5e-128 426.3 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1237) C2 PF00168.25 KLO12853.1 - 2.9e-10 39.8 0.0 7.5e-10 38.5 0.0 1.7 2 0 0 2 2 2 1 C2 domain NUFIP1 PF10453.4 KLO12854.1 - 0.012 15.1 0.6 0.026 14.0 0.4 1.5 1 0 0 1 1 1 0 Nuclear fragile X mental retardation-interacting protein 1 (NUFIP1) MnhB PF04039.8 KLO12854.1 - 0.082 12.9 0.0 0.097 12.7 0.0 1.1 1 0 0 1 1 1 0 Domain related to MnhB subunit of Na+/H+ antiporter Pedibin PF08182.6 KLO12855.1 - 0.13 11.8 0.1 0.6 9.6 0.1 2.0 2 0 0 2 2 2 0 Pedibin/Hym-346 family Myb_DNA-binding PF00249.26 KLO12857.1 - 1.9e-35 120.6 4.2 5.1e-10 39.2 0.0 5.8 5 1 0 5 5 5 5 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 KLO12857.1 - 6.6e-31 106.2 4.7 2.6e-10 40.2 0.1 5.4 3 2 2 5 5 5 5 Myb-like DNA-binding domain MADF_DNA_bdg PF10545.4 KLO12857.1 - 0.075 13.2 5.7 2.7 8.2 0.2 4.0 4 1 0 4 4 4 0 Alcohol dehydrogenase transcription factor Myb/SANT-like Bromo_TP PF07524.8 KLO12858.1 - 4.1e-07 29.6 0.1 7.3e-07 28.8 0.0 1.4 1 0 0 1 1 1 1 Bromodomain associated TAF8_C PF10406.4 KLO12858.1 - 2.2e-06 27.5 5.4 2.2e-06 27.5 3.8 1.9 2 0 0 2 2 2 1 Transcription factor TFIID complex subunit 8 C-term DUF788 PF05620.6 KLO12859.1 - 1.7e-41 141.8 0.0 2e-41 141.7 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF788) P120R PF08062.6 KLO12859.1 - 0.034 14.3 1.6 0.071 13.3 1.1 1.5 1 0 0 1 1 1 0 P120R (NUC006) repeat Rdx PF10262.4 KLO12860.1 - 1.2e-20 73.3 0.0 1.5e-20 72.9 0.0 1.2 1 0 0 1 1 1 1 Rdx family Peptidase_C48 PF02902.14 KLO12861.1 - 7.5e-14 51.8 0.0 1.2e-13 51.1 0.0 1.3 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain NAD_binding_8 PF13450.1 KLO12863.1 - 8.3e-12 44.9 0.0 2.5e-11 43.4 0.0 1.9 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 KLO12863.1 - 4.6e-08 32.3 0.0 5.9e-06 25.4 0.0 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 KLO12863.1 - 2.9e-06 27.5 0.0 0.045 14.1 0.0 2.6 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 KLO12863.1 - 4.6e-06 25.3 0.3 0.0045 15.5 0.1 2.2 2 0 0 2 2 2 2 HI0933-like protein NAD_binding_9 PF13454.1 KLO12863.1 - 4.7e-06 26.4 0.0 0.0003 20.6 0.0 2.6 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 KLO12863.1 - 7.5e-06 25.9 0.0 0.0027 17.6 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 KLO12863.1 - 8.1e-06 26.0 0.1 0.00019 21.5 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 KLO12863.1 - 2.1e-05 23.8 1.0 0.00094 18.3 0.0 2.6 3 0 0 3 3 3 1 FAD dependent oxidoreductase Thi4 PF01946.12 KLO12863.1 - 0.00014 21.0 0.0 0.00031 19.8 0.0 1.5 1 0 0 1 1 1 1 Thi4 family FAD_binding_2 PF00890.19 KLO12863.1 - 0.00027 19.9 0.0 0.00039 19.3 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Amino_oxidase PF01593.19 KLO12863.1 - 0.001 18.2 0.0 0.58 9.1 0.0 2.2 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase K_oxygenase PF13434.1 KLO12863.1 - 0.0055 15.6 0.0 0.89 8.4 0.0 2.4 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) FAD_binding_3 PF01494.14 KLO12863.1 - 0.011 14.8 0.0 0.61 9.0 0.0 2.2 2 0 0 2 2 2 0 FAD binding domain GIDA PF01134.17 KLO12863.1 - 0.014 14.2 0.3 0.035 12.9 0.1 1.7 2 0 0 2 2 2 0 Glucose inhibited division protein A Trp_halogenase PF04820.9 KLO12863.1 - 0.029 13.0 0.5 0.15 10.7 0.0 2.3 3 0 0 3 3 3 0 Tryptophan halogenase Shikimate_DH PF01488.15 KLO12863.1 - 0.04 14.0 0.0 0.077 13.0 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase NAD_Gly3P_dh_N PF01210.18 KLO12863.1 - 0.076 12.7 0.0 0.17 11.5 0.0 1.6 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus AlaDh_PNT_C PF01262.16 KLO12863.1 - 0.083 12.4 0.0 0.22 11.0 0.0 1.7 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Epimerase PF01370.16 KLO12865.1 - 5.9e-20 71.7 0.1 1.5e-19 70.4 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 KLO12865.1 - 9.8e-17 61.5 1.0 7.7e-16 58.6 0.7 2.2 1 1 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 KLO12865.1 - 1.2e-12 47.1 0.0 3.5e-12 45.6 0.0 1.8 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 KLO12865.1 - 7.9e-10 38.0 0.0 4.6e-08 32.2 0.0 2.2 1 1 0 1 1 1 1 Male sterility protein NmrA PF05368.8 KLO12865.1 - 1.7e-09 37.2 0.8 6.3e-09 35.4 0.4 1.9 2 0 0 2 2 2 1 NmrA-like family Polysacc_synt_2 PF02719.10 KLO12865.1 - 3.8e-05 22.7 0.0 0.0001 21.3 0.0 1.6 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein adh_short PF00106.20 KLO12865.1 - 5.2e-05 23.2 0.6 0.0004 20.3 0.4 2.1 1 1 0 1 1 1 1 short chain dehydrogenase RmlD_sub_bind PF04321.12 KLO12865.1 - 0.0021 16.9 0.1 2.5 6.9 0.0 3.0 2 1 0 2 2 2 2 RmlD substrate binding domain DFP PF04127.10 KLO12865.1 - 0.0066 16.0 0.1 0.058 12.9 0.0 2.0 2 0 0 2 2 2 1 DNA / pantothenate metabolism flavoprotein KR PF08659.5 KLO12865.1 - 0.022 14.4 2.2 3.6 7.2 1.5 2.2 1 1 0 1 1 1 0 KR domain Epimerase PF01370.16 KLO12866.1 - 3e-18 66.1 0.0 9.4e-18 64.5 0.0 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 KLO12866.1 - 2e-14 52.9 0.0 1.5e-13 50.0 0.0 2.3 2 1 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 KLO12866.1 - 2.2e-14 53.8 2.8 7.7e-14 52.1 1.9 2.0 1 1 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 KLO12866.1 - 3.8e-09 36.1 1.0 9.4e-09 34.8 0.6 1.7 2 0 0 2 2 2 1 NmrA-like family NAD_binding_4 PF07993.7 KLO12866.1 - 3.1e-08 32.8 0.0 0.002 17.0 0.0 2.2 2 0 0 2 2 2 2 Male sterility protein Polysacc_synt_2 PF02719.10 KLO12866.1 - 3e-06 26.3 0.0 0.00021 20.3 0.1 2.2 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein adh_short PF00106.20 KLO12866.1 - 0.00065 19.6 0.8 0.0052 16.7 0.5 2.2 1 1 0 1 1 1 1 short chain dehydrogenase RmlD_sub_bind PF04321.12 KLO12866.1 - 0.0078 15.1 0.2 0.66 8.8 0.1 3.1 3 1 0 3 3 3 1 RmlD substrate binding domain Fungal_trans PF04082.13 KLO12867.1 - 1.5e-08 33.8 0.0 2.9e-08 32.9 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Fungal_trans PF04082.13 KLO12869.1 - 8.7e-12 44.4 0.0 3.8e-11 42.3 0.0 2.0 2 1 0 2 2 2 1 Fungal specific transcription factor domain Fungal_trans PF04082.13 KLO12870.1 - 2.2e-09 36.5 0.6 3.9e-09 35.7 0.4 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KLO12871.1 - 1.1e-06 28.3 8.9 1.9e-06 27.6 6.2 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 KLO12871.1 - 0.0027 16.6 0.0 0.0058 15.5 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Pro-kuma_activ PF09286.6 KLO12872.1 - 3.3e-37 127.7 0.0 8.4e-37 126.3 0.0 1.7 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.17 KLO12872.1 - 5.4e-07 29.0 1.4 5.4e-07 29.0 1.0 1.9 2 0 0 2 2 2 1 Subtilase family adh_short PF00106.20 KLO12873.1 - 1.4e-31 109.6 0.5 2.2e-31 109.0 0.4 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KLO12873.1 - 8.1e-21 74.8 0.0 1.1e-20 74.4 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KLO12873.1 - 1.3e-15 57.4 0.7 3.2e-15 56.2 0.3 1.7 1 1 1 2 2 2 1 KR domain Epimerase PF01370.16 KLO12873.1 - 4.4e-08 32.8 0.2 1e-07 31.6 0.1 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 KLO12873.1 - 8.6e-05 22.6 1.7 0.00024 21.1 0.8 1.8 2 0 0 2 2 2 1 NADH(P)-binding NmrA PF05368.8 KLO12873.1 - 0.00082 18.6 1.0 0.0015 17.7 0.7 1.4 1 0 0 1 1 1 1 NmrA-like family RmlD_sub_bind PF04321.12 KLO12873.1 - 0.015 14.1 0.1 0.025 13.4 0.1 1.3 1 0 0 1 1 1 0 RmlD substrate binding domain Eno-Rase_NADH_b PF12242.3 KLO12873.1 - 0.023 14.4 0.2 0.045 13.5 0.1 1.5 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase 3HCDH_N PF02737.13 KLO12873.1 - 0.025 14.2 0.3 0.043 13.4 0.2 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3Beta_HSD PF01073.14 KLO12873.1 - 0.038 12.6 0.1 0.055 12.1 0.1 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Shikimate_DH PF01488.15 KLO12873.1 - 0.044 13.8 0.1 0.071 13.2 0.1 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase CW_binding_2 PF04122.7 KLO12873.1 - 0.047 13.8 0.0 0.098 12.8 0.0 1.5 1 0 0 1 1 1 0 Putative cell wall binding repeat 2 F420_oxidored PF03807.12 KLO12873.1 - 0.089 13.2 0.2 0.21 12.0 0.1 1.7 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Sterol_MT_C PF08498.5 KLO12876.1 - 2.8e-26 91.2 0.1 4.5e-26 90.5 0.1 1.3 1 0 0 1 1 1 1 Sterol methyltransferase C-terminal Methyltransf_31 PF13847.1 KLO12876.1 - 5.4e-19 68.2 0.0 1e-18 67.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KLO12876.1 - 7.6e-19 67.9 0.0 1.4e-18 67.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KLO12876.1 - 8e-14 51.9 0.0 1.7e-13 50.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KLO12876.1 - 1.9e-13 50.4 0.0 3e-13 49.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 KLO12876.1 - 2e-13 50.0 0.0 2.7e-13 49.6 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_18 PF12847.2 KLO12876.1 - 2.2e-13 50.7 0.0 1.6e-12 48.0 0.0 2.3 3 1 0 3 3 3 1 Methyltransferase domain Methyltransf_26 PF13659.1 KLO12876.1 - 5.8e-13 48.9 0.0 1.4e-12 47.6 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KLO12876.1 - 1.9e-11 44.2 0.0 3.2e-11 43.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KLO12876.1 - 1.4e-08 34.1 0.0 2.5e-08 33.3 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.9 KLO12876.1 - 1e-05 24.9 0.0 2e-05 24.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_3 PF01596.12 KLO12876.1 - 4.3e-05 22.6 0.0 7e-05 21.9 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_15 PF09445.5 KLO12876.1 - 0.00012 21.6 0.1 0.00018 21.1 0.0 1.2 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase PCMT PF01135.14 KLO12876.1 - 0.00013 21.5 0.0 0.00019 21.0 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MetW PF07021.7 KLO12876.1 - 0.00031 20.1 0.0 0.00052 19.4 0.0 1.3 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_24 PF13578.1 KLO12876.1 - 0.0019 19.0 0.0 0.0068 17.2 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain UPF0020 PF01170.13 KLO12876.1 - 0.011 15.3 0.0 0.016 14.7 0.0 1.3 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 Methyltransf_2 PF00891.13 KLO12876.1 - 0.013 14.7 0.0 0.021 14.0 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase Spermine_synth PF01564.12 KLO12876.1 - 0.035 13.0 0.0 0.069 12.0 0.0 1.4 1 1 0 1 1 1 0 Spermine/spermidine synthase PrmA PF06325.8 KLO12876.1 - 0.14 11.2 0.0 0.22 10.6 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Aldo_ket_red PF00248.16 KLO12877.1 - 4.4e-55 186.5 0.0 5.2e-55 186.2 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family GMC_oxred_N PF00732.14 KLO12878.1 - 4.1e-16 58.9 0.0 1.3e-15 57.3 0.0 1.9 1 1 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 KLO12878.1 - 1.3e-13 51.4 0.1 4.4e-13 49.7 0.1 2.0 1 1 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 KLO12878.1 - 2.6e-10 39.7 0.3 1.9e-05 23.7 0.2 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 KLO12878.1 - 8.9e-06 24.8 0.7 4.8e-05 22.3 0.1 2.0 2 0 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.1 KLO12878.1 - 1.2e-05 25.2 0.0 3.3e-05 23.8 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.14 KLO12878.1 - 0.0002 20.5 0.2 0.0003 19.9 0.2 1.2 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.9 KLO12878.1 - 0.00035 19.1 0.1 0.00079 18.0 0.0 1.6 2 0 0 2 2 2 1 HI0933-like protein Thi4 PF01946.12 KLO12878.1 - 0.0008 18.5 0.1 0.0085 15.2 0.0 2.1 2 0 0 2 2 2 1 Thi4 family Pyr_redox_3 PF13738.1 KLO12878.1 - 0.0011 19.1 0.1 0.0086 16.1 0.1 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 KLO12878.1 - 0.0019 17.3 0.4 0.016 14.2 0.1 2.0 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 KLO12878.1 - 0.0026 17.6 0.0 0.0044 16.9 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 KLO12878.1 - 0.12 12.7 0.2 1.3 9.4 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase GMC_oxred_C PF05199.8 KLO12879.1 - 7.5e-14 52.2 0.1 1.9e-13 50.9 0.1 1.7 1 1 0 1 1 1 1 GMC oxidoreductase GMC_oxred_N PF00732.14 KLO12879.1 - 4.7e-11 42.3 0.0 4e-05 22.9 0.0 2.4 2 0 0 2 2 2 2 GMC oxidoreductase DAO PF01266.19 KLO12879.1 - 8.1e-11 41.4 0.1 1.1e-05 24.5 0.1 2.4 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KLO12879.1 - 1e-05 25.4 0.1 3.1e-05 23.9 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 KLO12879.1 - 2.4e-05 23.3 0.2 6.7e-05 21.9 0.0 1.7 2 0 0 2 2 2 1 FAD binding domain FAD_binding_3 PF01494.14 KLO12879.1 - 0.00012 21.2 0.2 0.00018 20.6 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.9 KLO12879.1 - 0.00022 19.8 0.0 0.0004 18.9 0.0 1.4 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox_2 PF07992.9 KLO12879.1 - 0.0012 18.7 0.1 0.0022 17.9 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 KLO12879.1 - 0.0023 17.0 0.0 0.02 13.9 0.0 2.1 2 0 0 2 2 2 1 Thi4 family Pyr_redox_3 PF13738.1 KLO12879.1 - 0.007 16.4 0.1 0.022 14.8 0.1 1.9 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 KLO12879.1 - 0.045 12.8 0.1 0.25 10.3 0.0 2.0 2 0 0 2 2 2 0 FAD dependent oxidoreductase DUF1761 PF08570.5 KLO12880.1 - 0.0046 16.9 0.0 3.4 7.6 0.6 2.5 2 1 0 2 2 2 2 Protein of unknown function (DUF1761) Exc PF07825.6 KLO12881.1 - 0.093 12.5 0.7 1.1 9.0 0.1 2.3 2 0 0 2 2 2 0 Excisionase-like protein Pkinase PF00069.20 KLO12884.1 - 1.2e-47 162.2 0.0 1.6e-47 161.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KLO12884.1 - 6.1e-42 143.4 0.0 8.1e-42 143.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KLO12884.1 - 0.00058 18.9 0.0 0.0011 18.0 0.0 1.3 1 1 0 1 1 1 1 Kinase-like WD40 PF00400.27 KLO12885.1 - 1.8e-22 78.3 1.1 4.5e-08 32.6 0.2 3.5 3 0 0 3 3 3 3 WD domain, G-beta repeat Nup160 PF11715.3 KLO12885.1 - 0.0074 14.4 0.0 0.0096 14.1 0.0 1.2 1 0 0 1 1 1 1 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.11 KLO12885.1 - 0.043 12.1 0.1 1.4 7.1 0.0 2.7 2 2 1 3 3 3 0 Cytochrome D1 heme domain Me-amine-dh_H PF06433.6 KLO12885.1 - 0.11 11.1 0.0 0.16 10.5 0.0 1.3 1 0 0 1 1 1 0 Methylamine dehydrogenase heavy chain (MADH) F-box-like PF12937.2 KLO12886.1 - 1.1e-05 25.1 2.6 3e-05 23.6 1.8 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KLO12886.1 - 2.8e-05 23.6 2.8 7e-05 22.3 2.0 1.6 1 0 0 1 1 1 1 F-box domain Peptidase_C26 PF07722.8 KLO12886.1 - 0.047 13.1 0.0 1.1 8.6 0.0 2.1 2 0 0 2 2 2 0 Peptidase C26 Pkinase PF00069.20 KLO12887.1 - 2.5e-61 207.1 0.0 3.1e-61 206.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KLO12887.1 - 9.5e-27 93.6 0.0 1.2e-26 93.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KLO12887.1 - 5e-06 25.6 0.0 8.6e-06 24.9 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 KLO12887.1 - 0.011 15.4 0.0 0.029 14.1 0.0 1.6 2 0 0 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.9 KLO12887.1 - 0.016 14.2 0.0 0.025 13.6 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.6 KLO12887.1 - 0.18 10.6 0.0 0.29 9.9 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 SIS PF01380.17 KLO12888.1 - 1.8e-61 205.5 0.1 2.9e-32 111.0 0.0 2.5 2 0 0 2 2 2 2 SIS domain GATase_2 PF00310.16 KLO12888.1 - 2.1e-26 92.5 0.4 1.4e-19 70.0 0.0 2.2 2 0 0 2 2 2 2 Glutamine amidotransferases class-II GATase_6 PF13522.1 KLO12888.1 - 6.5e-19 68.2 0.0 1.3e-18 67.2 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.1 KLO12888.1 - 5.7e-13 48.6 0.0 1.2e-12 47.6 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_4 PF13230.1 KLO12888.1 - 1.2e-09 37.2 0.0 2e-09 36.5 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferases class-II SIS_2 PF13580.1 KLO12888.1 - 0.047 13.4 0.0 0.25 11.0 0.0 2.3 2 1 1 3 3 3 0 SIS domain WD40 PF00400.27 KLO12889.1 - 5e-42 140.3 28.7 3.8e-08 32.8 1.5 11.5 11 0 0 11 11 11 7 WD domain, G-beta repeat eIF2A PF08662.6 KLO12889.1 - 2.4e-13 50.2 1.7 1.3e-05 24.9 0.0 4.9 2 2 2 5 5 5 3 Eukaryotic translation initiation factor eIF2A Coatomer_WDAD PF04053.9 KLO12889.1 - 4.7e-07 28.9 0.5 0.16 10.7 0.0 3.0 2 1 1 3 3 3 3 Coatomer WD associated region PQQ_2 PF13360.1 KLO12889.1 - 3.3e-06 26.7 10.3 0.015 14.7 0.4 3.1 1 1 2 3 3 3 3 PQQ-like domain Nbas_N PF15492.1 KLO12889.1 - 0.00033 19.8 0.3 2.5 7.1 0.0 3.8 3 1 1 4 4 4 1 Neuroblastoma-amplified sequence, N terminal IKI3 PF04762.7 KLO12889.1 - 0.00076 17.4 0.2 0.86 7.3 0.0 2.6 1 1 0 2 2 2 2 IKI3 family Nup160 PF11715.3 KLO12889.1 - 0.00094 17.4 1.1 0.003 15.7 0.3 2.1 1 1 1 2 2 2 1 Nucleoporin Nup120/160 PD40 PF07676.7 KLO12889.1 - 0.0015 18.1 0.2 12 5.7 0.0 3.9 3 0 0 3 3 3 1 WD40-like Beta Propeller Repeat Lactonase PF10282.4 KLO12889.1 - 0.0043 16.1 0.0 0.011 14.8 0.0 1.6 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller TFIIIC_delta PF12657.2 KLO12889.1 - 0.0061 16.2 0.3 0.12 12.0 0.0 3.0 2 1 0 2 2 2 1 Transcription factor IIIC subunit delta N-term BBS2_Mid PF14783.1 KLO12889.1 - 0.023 14.4 0.4 60 3.4 0.0 4.8 4 1 1 5 5 5 0 Ciliary BBSome complex subunit 2, middle region PQQ_3 PF13570.1 KLO12889.1 - 0.24 11.7 0.0 0.24 11.7 0.0 6.4 8 0 0 8 8 8 0 PQQ-like domain Abhydrolase_6 PF12697.2 KLO12890.1 - 2e-21 76.9 0.0 3e-21 76.3 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KLO12890.1 - 3.3e-09 36.6 0.3 5.4e-08 32.6 0.2 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KLO12890.1 - 8.5e-09 35.3 0.1 1e-08 35.0 0.1 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 KLO12890.1 - 6.8e-05 22.6 0.0 0.00013 21.7 0.0 1.5 1 0 0 1 1 1 1 Putative lysophospholipase Oxidored_q2 PF00420.19 KLO12892.1 - 0.0046 16.5 3.0 0.0073 15.8 0.5 2.5 1 1 0 1 1 1 1 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L DUF2101 PF09874.4 KLO12894.1 - 4.5 6.7 13.3 0.43 10.0 1.6 2.4 2 1 0 2 2 2 0 Predicted membrane protein (DUF2101) RRM_1 PF00076.17 KLO12901.1 - 3.7e-27 93.7 0.0 1.7e-17 62.7 0.0 3.0 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KLO12901.1 - 1.6e-21 76.0 0.0 2e-12 46.8 0.0 2.5 2 1 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KLO12901.1 - 3.8e-10 39.4 0.0 0.00012 21.8 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Metallophos PF00149.23 KLO12903.1 - 1.4e-14 53.9 2.5 2.2e-14 53.3 1.7 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase MDM1 PF15501.1 KLO12904.1 - 0.13 11.2 4.7 0.14 11.1 3.3 1.0 1 0 0 1 1 1 0 Nuclear protein MDM1 Histone PF00125.19 KLO12905.1 - 1.3e-21 76.4 0.4 2e-21 75.8 0.3 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 KLO12905.1 - 2.2e-06 27.5 0.1 5e-06 26.4 0.1 1.6 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.8 KLO12905.1 - 0.00026 21.2 0.0 0.00043 20.5 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A Bt_P21 PF05560.6 KLO12905.1 - 0.069 12.5 0.0 0.085 12.2 0.0 1.1 1 0 0 1 1 1 0 Bacillus thuringiensis P21 molecular chaperone protein ORC3_N PF07034.6 KLO12905.1 - 0.092 11.6 0.1 0.11 11.3 0.1 1.0 1 0 0 1 1 1 0 Origin recognition complex (ORC) subunit 3 N-terminus Histone PF00125.19 KLO12906.1 - 4.5e-26 90.7 0.0 5.7e-26 90.4 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 KLO12906.1 - 3.9e-06 26.8 0.0 5.2e-06 26.4 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone RicinB_lectin_2 PF14200.1 KLO12908.1 - 7.6e-07 29.4 0.3 1.4e-05 25.3 0.0 2.7 2 1 1 3 3 3 2 Ricin-type beta-trefoil lectin domain-like zf-RING_2 PF13639.1 KLO12909.1 - 5e-10 39.0 10.3 7.4e-10 38.4 7.2 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 KLO12909.1 - 7.2e-10 38.3 9.0 1.1e-09 37.8 6.2 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KLO12909.1 - 3e-08 33.5 10.5 4.6e-08 32.9 7.3 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KLO12909.1 - 4.4e-07 29.4 10.4 6.5e-07 28.9 7.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KLO12909.1 - 9.4e-06 25.2 12.2 2.3e-05 24.0 8.5 1.6 1 1 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 KLO12909.1 - 3.3e-05 23.6 6.5 9.3e-05 22.2 4.5 1.7 1 1 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.2 KLO12909.1 - 0.00032 20.7 5.3 0.0005 20.1 3.7 1.3 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_6 PF14835.1 KLO12909.1 - 0.00074 19.2 2.7 0.0014 18.3 1.9 1.4 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-RING_4 PF14570.1 KLO12909.1 - 0.0008 18.9 7.1 0.0018 17.8 4.9 1.5 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-RING_UBOX PF13445.1 KLO12909.1 - 0.024 14.3 4.0 0.024 14.3 2.8 2.2 1 1 1 2 2 2 0 RING-type zinc-finger Siva PF05458.7 KLO12909.1 - 0.081 12.4 2.2 0.13 11.8 1.6 1.4 1 0 0 1 1 1 0 Cd27 binding protein (Siva) Rtf2 PF04641.7 KLO12909.1 - 0.084 12.0 0.2 0.12 11.5 0.1 1.4 1 0 0 1 1 1 0 Rtf2 RING-finger Prok-RING_2 PF14445.1 KLO12909.1 - 0.092 12.7 4.8 0.29 11.0 3.3 1.8 1 1 0 1 1 1 0 Prokaryotic RING finger family 2 zf-Apc11 PF12861.2 KLO12909.1 - 0.093 12.5 3.4 0.14 12.0 2.4 1.2 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger CDC45 PF02724.9 KLO12909.1 - 0.097 10.6 2.0 0.11 10.4 1.4 1.0 1 0 0 1 1 1 0 CDC45-like protein Prok-RING_4 PF14447.1 KLO12909.1 - 0.27 10.8 8.3 1 8.9 5.7 1.9 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 TFIIF_alpha PF05793.7 KLO12909.1 - 0.36 9.1 4.8 0.48 8.7 3.3 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) CENP-B_dimeris PF09026.5 KLO12909.1 - 0.79 9.9 6.4 1.3 9.2 4.4 1.3 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Zn_Tnp_IS91 PF14319.1 KLO12909.1 - 1.6 8.2 7.5 0.37 10.3 1.5 2.0 1 1 1 2 2 2 0 Transposase zinc-binding domain NUDIX PF00293.23 KLO12910.1 - 5.1e-11 42.3 0.3 7.5e-11 41.8 0.1 1.4 1 1 0 1 1 1 1 NUDIX domain MC1 PF05854.6 KLO12910.1 - 0.006 16.5 0.0 0.013 15.4 0.0 1.7 1 1 0 1 1 1 1 Non-histone chromosomal protein MC1 Pkinase PF00069.20 KLO12911.1 - 2e-67 227.0 0.0 2.9e-67 226.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KLO12911.1 - 6.9e-32 110.5 0.0 1e-31 109.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.17 KLO12911.1 - 0.24 10.7 1.2 1.2 8.4 0.8 2.2 1 1 0 1 1 1 0 RIO1 family p450 PF00067.17 KLO12912.1 - 3.4e-133 444.5 0.0 7.4e-67 225.8 0.0 2.2 2 0 0 2 2 2 2 Cytochrome P450 CysG_dimeriser PF10414.4 KLO12912.1 - 0.88 9.0 3.5 15 5.1 0.1 2.9 3 0 0 3 3 3 0 Sirohaem synthase dimerisation region Glyco_hydro_12 PF01670.11 KLO12913.1 - 1.8e-33 115.5 2.4 1.8e-33 115.5 1.6 1.5 1 1 0 1 1 1 1 Glycosyl hydrolase family 12 Methyltransf_23 PF13489.1 KLO12914.1 - 5e-14 52.3 0.0 7.1e-14 51.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KLO12914.1 - 3.1e-13 49.5 0.0 2.3e-07 30.5 0.0 2.2 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_11 PF08241.7 KLO12914.1 - 6.8e-09 36.1 0.0 1.5e-08 35.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KLO12914.1 - 1.7e-08 34.7 0.0 1.4e-07 31.8 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KLO12914.1 - 9.1e-07 29.4 0.0 3.5e-05 24.3 0.0 2.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 KLO12914.1 - 0.00023 20.2 0.0 0.00038 19.5 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_25 PF13649.1 KLO12914.1 - 0.0072 16.6 0.0 0.021 15.1 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain GidB PF02527.10 KLO12914.1 - 0.0095 15.0 0.0 0.072 12.2 0.0 2.0 1 1 0 1 1 1 1 rRNA small subunit methyltransferase G Methyltransf_2 PF00891.13 KLO12914.1 - 0.022 13.9 0.0 0.034 13.3 0.0 1.2 1 0 0 1 1 1 0 O-methyltransferase CheR PF01739.13 KLO12914.1 - 0.056 12.7 0.0 0.094 11.9 0.0 1.3 1 0 0 1 1 1 0 CheR methyltransferase, SAM binding domain PrmA PF06325.8 KLO12914.1 - 0.073 12.1 0.0 0.1 11.6 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) PCMT PF01135.14 KLO12914.1 - 0.12 11.9 0.0 0.35 10.3 0.0 1.7 2 0 0 2 2 2 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MTS PF05175.9 KLO12914.1 - 0.15 11.4 0.0 0.33 10.3 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_23 PF13489.1 KLO12915.1 - 2.5e-19 69.5 0.0 3.7e-19 69.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KLO12915.1 - 1.6e-18 66.7 0.0 3.7e-18 65.5 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KLO12915.1 - 1.5e-10 41.3 0.0 3e-10 40.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KLO12915.1 - 1e-09 38.7 0.0 3.1e-09 37.1 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KLO12915.1 - 1.4e-08 35.3 0.0 6.5e-08 33.1 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KLO12915.1 - 4.6e-07 30.1 0.0 9.9e-07 29.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 KLO12915.1 - 5e-07 29.1 0.0 9e-07 28.3 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) GidB PF02527.10 KLO12915.1 - 2.7e-06 26.6 0.0 5.7e-06 25.5 0.0 1.4 1 1 0 1 1 1 1 rRNA small subunit methyltransferase G Methyltransf_PK PF05891.7 KLO12915.1 - 3.8e-06 26.3 0.0 6.1e-06 25.6 0.0 1.3 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase Methyltransf_26 PF13659.1 KLO12915.1 - 4.4e-05 23.4 0.0 0.00011 22.2 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 KLO12915.1 - 4.8e-05 22.4 0.0 0.00079 18.5 0.0 2.2 2 0 0 2 2 2 1 Putative methyltransferase MTS PF05175.9 KLO12915.1 - 0.00056 19.3 0.0 0.0014 18.0 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase small domain FtsJ PF01728.14 KLO12915.1 - 0.0014 18.6 0.0 0.0022 18.0 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_15 PF09445.5 KLO12915.1 - 0.014 14.9 0.0 0.03 13.8 0.0 1.6 2 0 0 2 2 2 0 RNA cap guanine-N2 methyltransferase Methyltransf_16 PF10294.4 KLO12915.1 - 0.017 14.5 0.0 0.03 13.7 0.0 1.4 1 0 0 1 1 1 0 Putative methyltransferase Met_10 PF02475.11 KLO12915.1 - 0.019 14.5 0.0 0.039 13.5 0.0 1.5 2 0 0 2 2 2 0 Met-10+ like-protein Methyltransf_9 PF08003.6 KLO12915.1 - 0.04 12.5 0.0 0.089 11.4 0.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1698) PCMT PF01135.14 KLO12915.1 - 0.047 13.2 0.0 0.085 12.3 0.0 1.4 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Ubie_methyltran PF01209.13 KLO12915.1 - 0.064 12.3 0.0 0.23 10.5 0.0 1.9 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family RrnaAD PF00398.15 KLO12915.1 - 0.081 11.9 0.0 0.13 11.2 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase DOT1 PF08123.8 KLO12915.1 - 0.085 12.1 0.0 0.14 11.4 0.0 1.3 1 0 0 1 1 1 0 Histone methylation protein DOT1 Methyltransf_8 PF05148.10 KLO12915.1 - 0.096 12.2 0.0 0.15 11.6 0.0 1.2 1 0 0 1 1 1 0 Hypothetical methyltransferase Peptidase_M19 PF01244.16 KLO12916.1 - 2e-104 348.9 0.0 1.1e-103 346.5 0.0 1.8 1 1 0 1 1 1 1 Membrane dipeptidase (Peptidase family M19) p450 PF00067.17 KLO12917.1 - 8.3e-63 212.5 0.0 5.3e-62 209.8 0.0 2.1 1 1 0 1 1 1 1 Cytochrome P450 DEAD PF00270.24 KLO12918.1 - 5.1e-23 81.3 0.1 1.9e-20 73.0 0.0 2.2 2 0 0 2 2 2 2 DEAD/DEAH box helicase Helicase_C PF00271.26 KLO12918.1 - 3e-18 65.4 0.1 6.7e-18 64.3 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain RQC PF09382.5 KLO12918.1 - 3.1e-15 55.8 0.0 3.6e-14 52.3 0.0 2.3 2 0 0 2 2 2 1 RQC domain ResIII PF04851.10 KLO12918.1 - 2.1e-05 24.4 0.0 6e-05 22.9 0.0 1.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit FAD_binding_2 PF00890.19 KLO12919.1 - 8.9e-87 291.6 1.6 1.1e-86 291.2 1.1 1.1 1 0 0 1 1 1 1 FAD binding domain Cyt-b5 PF00173.23 KLO12919.1 - 4.2e-23 80.9 0.0 8.9e-23 79.8 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain DAO PF01266.19 KLO12919.1 - 6.3e-13 48.3 1.5 4.7e-12 45.4 1.0 2.0 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 KLO12919.1 - 8.2e-12 45.4 0.1 1.5e-09 38.0 0.0 3.2 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KLO12919.1 - 6.7e-11 42.0 0.2 8.7e-10 38.4 0.1 3.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.2 KLO12919.1 - 1.3e-08 34.3 0.2 2.1e-08 33.6 0.2 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.9 KLO12919.1 - 4e-07 28.8 2.8 5.7e-05 21.7 0.2 3.1 3 0 0 3 3 3 1 HI0933-like protein GIDA PF01134.17 KLO12919.1 - 1.2e-06 27.6 0.9 6.9e-05 21.8 0.2 2.9 3 0 0 3 3 3 1 Glucose inhibited division protein A FAD_binding_3 PF01494.14 KLO12919.1 - 1.6e-06 27.4 0.8 2.9e-06 26.5 0.6 1.4 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.1 KLO12919.1 - 3.5e-06 27.2 0.3 1e-05 25.7 0.2 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 KLO12919.1 - 9.1e-06 24.9 0.4 0.0033 16.5 0.1 2.5 2 0 0 2 2 2 2 Thi4 family NAD_binding_9 PF13454.1 KLO12919.1 - 0.00018 21.2 0.3 0.0039 16.9 0.2 2.4 1 1 0 1 1 1 1 FAD-NAD(P)-binding Amino_oxidase PF01593.19 KLO12919.1 - 0.00032 19.9 0.2 0.0059 15.7 0.0 2.7 3 0 0 3 3 3 1 Flavin containing amine oxidoreductase Lycopene_cycl PF05834.7 KLO12919.1 - 0.0012 17.8 0.2 0.0067 15.3 0.1 2.0 2 0 0 2 2 2 1 Lycopene cyclase protein Pyr_redox PF00070.22 KLO12919.1 - 0.003 17.9 0.4 0.025 14.9 0.0 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.1 KLO12919.1 - 0.016 15.4 0.0 0.033 14.4 0.0 1.6 1 0 0 1 1 1 0 Putative NAD(P)-binding AlaDh_PNT_C PF01262.16 KLO12919.1 - 0.019 14.5 0.2 0.043 13.3 0.2 1.6 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain 3HCDH_N PF02737.13 KLO12919.1 - 0.083 12.5 0.1 0.15 11.6 0.1 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Period_C PF12114.3 KLO12919.1 - 1.4 8.4 6.4 2.5 7.6 4.5 1.3 1 0 0 1 1 1 0 Period protein 2/3C-terminal region FAD_binding_3 PF01494.14 KLO12920.1 - 5.1e-20 71.8 0.1 1.6e-19 70.1 0.1 1.7 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 KLO12920.1 - 7.6e-06 25.0 0.0 1.8e-05 23.8 0.0 1.6 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KLO12920.1 - 7.3e-05 22.7 0.1 0.00016 21.5 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 KLO12920.1 - 0.00042 20.6 0.5 0.028 14.8 0.3 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 KLO12920.1 - 0.00067 19.4 0.1 0.0014 18.4 0.1 1.7 1 1 0 1 1 1 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 KLO12920.1 - 0.0024 17.7 0.6 0.0062 16.4 0.4 1.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 KLO12920.1 - 0.0075 14.9 0.5 0.021 13.4 0.2 1.8 2 0 0 2 2 2 1 Tryptophan halogenase Pyr_redox_3 PF13738.1 KLO12920.1 - 0.014 15.4 0.3 0.21 11.6 0.2 2.2 1 1 1 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 KLO12920.1 - 0.038 12.8 0.5 0.079 11.7 0.4 1.5 1 0 0 1 1 1 0 FAD binding domain Lycopene_cycl PF05834.7 KLO12920.1 - 0.077 11.9 1.4 0.12 11.3 0.1 1.8 2 0 0 2 2 2 0 Lycopene cyclase protein GIDA PF01134.17 KLO12920.1 - 0.29 9.9 1.5 0.44 9.3 1.0 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A DAO PF01266.19 KLO12921.1 - 9.5e-23 80.6 0.0 1.4e-22 80.1 0.0 1.2 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_7 PF13241.1 KLO12921.1 - 0.0011 19.1 0.0 0.002 18.3 0.0 1.3 1 0 0 1 1 1 1 Putative NAD(P)-binding FAD_binding_2 PF00890.19 KLO12921.1 - 0.0018 17.1 0.0 0.0028 16.5 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 KLO12921.1 - 0.0022 17.8 0.0 0.0048 16.7 0.0 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 KLO12921.1 - 0.018 15.1 0.0 0.025 14.6 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 KLO12921.1 - 0.047 14.0 1.0 0.11 12.9 0.7 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.13 KLO12921.1 - 0.049 13.2 0.0 0.069 12.8 0.0 1.2 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_8 PF13450.1 KLO12921.1 - 0.062 13.3 0.5 0.16 11.9 0.3 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Zn_clus PF00172.13 KLO12922.1 - 8.1e-07 28.8 12.4 1.3e-06 28.1 8.6 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TFIIF_alpha PF05793.7 KLO12922.1 - 0.6 8.4 6.6 0.87 7.8 4.6 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Robl_LC7 PF03259.12 KLO12924.1 - 2.4e-07 30.2 0.0 4.9e-07 29.2 0.0 1.6 1 1 0 1 1 1 1 Roadblock/LC7 domain zf-MYND PF01753.13 KLO12925.1 - 1.2e-05 25.1 12.9 4e-05 23.3 8.9 2.0 1 0 0 1 1 1 1 MYND finger FAD_binding_3 PF01494.14 KLO12927.1 - 1.1e-20 74.0 0.0 1.6e-20 73.4 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.22 KLO12927.1 - 6e-05 23.3 0.4 0.02 15.3 0.2 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 KLO12927.1 - 6.6e-05 21.9 0.0 0.00015 20.8 0.0 1.6 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 KLO12927.1 - 0.00029 20.6 0.1 0.00085 19.1 0.0 2.0 1 1 0 1 1 1 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.1 KLO12927.1 - 0.0012 18.8 0.1 0.0028 17.6 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.9 KLO12927.1 - 0.0029 16.1 1.9 0.033 12.6 0.5 2.1 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox_3 PF13738.1 KLO12927.1 - 0.0035 17.4 0.0 0.0075 16.3 0.0 1.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 KLO12927.1 - 0.0036 15.9 0.2 0.0089 14.6 0.0 1.7 2 0 0 2 2 2 1 Tryptophan halogenase Pyr_redox_2 PF07992.9 KLO12927.1 - 0.032 14.1 0.5 0.059 13.2 0.4 1.6 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase HTH_32 PF13565.1 KLO12927.1 - 0.039 14.7 0.6 8.6 7.2 0.0 3.3 2 1 1 3 3 3 0 Homeodomain-like domain MFS_1 PF07690.11 KLO12928.1 - 9.7e-27 93.5 24.3 9.7e-27 93.5 16.8 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KLO12928.1 - 1.1e-12 47.3 0.6 1.1e-12 47.3 0.4 2.6 2 1 0 3 3 3 1 Sugar (and other) transporter MFS_2 PF13347.1 KLO12928.1 - 2.4e-05 22.9 13.8 3.2e-05 22.5 1.7 2.9 1 1 0 2 2 2 2 MFS/sugar transport protein TRI12 PF06609.8 KLO12928.1 - 0.0036 15.5 0.9 0.0063 14.7 0.6 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) PS_Dcarbxylase PF02666.10 KLO12929.1 - 4.7e-48 163.1 0.0 6.4e-48 162.7 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase adh_short PF00106.20 KLO12930.1 - 4e-13 49.6 0.1 6.6e-13 48.9 0.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KLO12930.1 - 8.1e-08 32.3 0.0 1e-07 31.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KLO12930.1 - 0.00011 21.9 0.0 0.00016 21.3 0.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 KLO12930.1 - 0.00027 20.4 0.0 0.00049 19.6 0.0 1.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF830 PF05708.7 KLO12930.1 - 0.017 15.1 0.1 0.035 14.0 0.0 1.5 1 0 0 1 1 1 0 Orthopoxvirus protein of unknown function (DUF830) Dynamin_M PF01031.15 KLO12931.1 - 1.3e-26 93.0 0.1 8.3e-19 67.4 0.0 2.2 2 0 0 2 2 2 2 Dynamin central region Dynamin_N PF00350.18 KLO12931.1 - 1.6e-26 93.0 0.0 4.8e-26 91.5 0.0 1.8 2 0 0 2 2 2 1 Dynamin family MMR_HSR1 PF01926.18 KLO12931.1 - 1.5e-06 28.1 0.0 1.2e-05 25.2 0.0 2.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 KLO12931.1 - 0.0015 19.0 0.0 0.0052 17.2 0.0 2.0 1 0 0 1 1 1 1 Miro-like protein GED PF02212.13 KLO12931.1 - 0.0031 17.3 0.0 0.075 12.9 0.0 2.8 2 0 0 2 2 2 1 Dynamin GTPase effector domain AAA_28 PF13521.1 KLO12931.1 - 0.032 14.1 0.0 0.12 12.3 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.1 KLO12931.1 - 0.037 13.5 0.1 0.075 12.5 0.1 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_16 PF13191.1 KLO12931.1 - 0.05 13.5 0.2 0.64 9.9 0.0 2.8 3 1 0 3 3 3 0 AAA ATPase domain ABC_tran PF00005.22 KLO12931.1 - 0.1 12.9 0.0 0.27 11.5 0.0 1.7 1 0 0 1 1 1 0 ABC transporter MobB PF03205.9 KLO12931.1 - 0.11 12.2 0.3 3.7 7.2 0.0 2.4 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B zf-CHY PF05495.7 KLO12934.1 - 1.3e-15 57.2 17.9 1.7e-15 56.8 12.4 1.1 1 0 0 1 1 1 1 CHY zinc finger zf-FPG_IleRS PF06827.9 KLO12934.1 - 0.0021 17.6 1.0 0.0064 16.1 0.4 2.0 2 0 0 2 2 2 1 Zinc finger found in FPG and IleRS Zn-ribbon_8 PF09723.5 KLO12934.1 - 0.02 14.8 3.8 0.02 14.8 2.6 2.6 2 1 0 2 2 2 0 Zinc ribbon domain Zn_Tnp_IS1595 PF12760.2 KLO12934.1 - 0.062 13.1 9.8 1.6 8.6 4.7 2.7 2 1 0 2 2 2 0 Transposase zinc-ribbon domain zinc_ribbon_2 PF13240.1 KLO12934.1 - 0.085 12.3 6.3 0.21 11.1 0.2 3.1 2 1 0 2 2 2 0 zinc-ribbon domain Cys_rich_KTR PF14205.1 KLO12934.1 - 0.27 10.7 5.4 3.3 7.2 1.3 2.5 1 1 1 2 2 2 0 Cysteine-rich KTR DZR PF12773.2 KLO12934.1 - 0.35 10.7 11.7 1.5 8.6 8.1 2.2 1 1 0 1 1 1 0 Double zinc ribbon DUF3797 PF12677.2 KLO12934.1 - 0.41 10.3 0.0 0.41 10.3 0.0 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF3797) zf-ribbon_3 PF13248.1 KLO12934.1 - 0.45 9.8 6.5 1.3 8.3 2.7 2.6 2 1 0 2 2 2 0 zinc-ribbon domain zf-H2C2_2 PF13465.1 KLO12934.1 - 0.54 10.6 0.2 0.54 10.6 0.1 3.1 3 0 0 3 3 3 0 Zinc-finger double domain C1_4 PF07975.7 KLO12934.1 - 0.59 10.1 12.1 0.61 10.1 2.4 2.6 1 1 2 3 3 3 0 TFIIH C1-like domain DNA_RNApol_7kD PF03604.8 KLO12934.1 - 0.63 9.5 4.2 2 7.9 0.1 3.1 3 0 0 3 3 3 0 DNA directed RNA polymerase, 7 kDa subunit RNA_POL_M_15KD PF02150.11 KLO12934.1 - 0.71 9.6 0.1 0.71 9.6 0.1 2.9 3 0 0 3 3 3 0 RNA polymerases M/15 Kd subunit Evr1_Alr PF04777.8 KLO12934.1 - 1 9.2 10.7 16 5.4 7.4 2.6 1 1 0 1 1 1 0 Erv1 / Alr family zf-RING_4 PF14570.1 KLO12934.1 - 1.1 8.9 13.2 4.8 6.8 0.1 3.0 2 1 0 2 2 2 0 RING/Ubox like zinc-binding domain Cytochrome_C7 PF14522.1 KLO12934.1 - 1.6 8.4 11.7 3.3 7.4 8.1 1.6 1 1 0 1 1 1 0 Cytochrome c7 GFA PF04828.9 KLO12934.1 - 1.8 8.5 9.3 2 8.4 4.6 2.4 1 1 1 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme NOB1_Zn_bind PF08772.6 KLO12934.1 - 2.8 7.8 7.1 0.4 10.5 2.0 1.8 1 1 1 2 2 2 0 Nin one binding (NOB1) Zn-ribbon like zf-RING_3 PF14369.1 KLO12934.1 - 3.7 7.6 9.2 0.93 9.5 2.2 2.5 1 1 2 3 3 3 0 zinc-finger TFIIS_C PF01096.13 KLO12934.1 - 5.3 6.7 11.5 34 4.1 0.1 3.2 2 1 1 3 3 3 0 Transcription factor S-II (TFIIS) zf-DNL PF05180.7 KLO12934.1 - 8 6.2 12.6 0.36 10.5 2.7 2.8 2 2 0 2 2 2 0 DNL zinc finger Baculo_PEP_C PF04513.7 KLO12935.1 - 1.7e-05 24.6 9.9 0.0086 15.9 1.3 2.5 1 1 1 2 2 2 2 Baculovirus polyhedron envelope protein, PEP, C terminus DUF4404 PF14357.1 KLO12935.1 - 0.1 13.0 0.3 0.16 12.3 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4404) DALR_2 PF09190.6 KLO12935.1 - 0.13 12.5 1.8 0.39 10.9 1.3 1.9 1 0 0 1 1 1 0 DALR domain DUF1700 PF08006.6 KLO12935.1 - 0.25 10.6 4.8 0.4 9.9 3.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1700) Rifin_STEVOR PF02009.11 KLO12935.1 - 2.4 7.7 6.0 3 7.3 4.2 1.1 1 0 0 1 1 1 0 Rifin/stevor family SurA_N PF09312.6 KLO12936.1 - 0.002 17.9 1.6 0.0028 17.5 1.1 1.1 1 0 0 1 1 1 1 SurA N-terminal domain DUF948 PF06103.6 KLO12936.1 - 0.015 15.1 0.4 0.036 13.9 0.3 1.7 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) Tropomyosin PF00261.15 KLO12936.1 - 0.075 12.1 0.1 0.1 11.6 0.0 1.2 1 0 0 1 1 1 0 Tropomyosin DUF3759 PF12585.3 KLO12937.1 - 9.7e-08 31.8 0.5 1.6e-07 31.1 0.3 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3759) HSP20 PF00011.16 KLO12938.1 - 0.016 15.0 0.0 0.025 14.4 0.0 1.2 1 0 0 1 1 1 0 Hsp20/alpha crystallin family GSIII_N PF12437.3 KLO12938.1 - 0.13 11.6 0.0 0.17 11.3 0.0 1.3 1 1 0 1 1 1 0 Glutamine synthetase type III N terminal HMG-CoA_red PF00368.13 KLO12939.1 - 7e-161 535.0 3.3 9.1e-161 534.6 2.3 1.1 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A reductase Sterol-sensing PF12349.3 KLO12939.1 - 1.2e-09 37.8 2.8 0.00024 20.5 0.1 2.7 3 0 0 3 3 3 2 Sterol-sensing domain of SREBP cleavage-activation Patched PF02460.13 KLO12939.1 - 0.093 10.6 1.5 0.21 9.4 1.1 1.5 1 1 0 1 1 1 0 Patched family HPIH PF13323.1 KLO12939.1 - 5 6.8 8.2 0.13 12.0 1.0 1.8 2 0 0 2 2 2 0 N-terminal domain with HPIH motif zf-MYND PF01753.13 KLO12940.1 - 1.3e-06 28.1 11.9 1.3e-06 28.1 8.3 1.7 2 0 0 2 2 2 1 MYND finger KH_1 PF00013.24 KLO12941.1 - 1.3e-09 37.5 0.0 9.8e-07 28.3 0.0 2.5 2 1 0 2 2 2 2 KH domain KH_3 PF13014.1 KLO12941.1 - 0.00012 21.6 0.6 0.0088 15.6 0.1 2.4 2 0 0 2 2 2 1 KH domain DUF4160 PF13711.1 KLO12941.1 - 0.011 15.5 0.1 0.03 14.1 0.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4160) DUF3745 PF12560.3 KLO12941.1 - 0.033 13.8 1.1 0.077 12.6 0.8 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3745) zf-C3HC4_3 PF13920.1 KLO12942.1 - 1.8e-09 37.0 2.5 1.8e-09 37.0 1.8 4.0 5 0 0 5 5 5 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KLO12942.1 - 6.8e-09 35.4 4.2 6.8e-09 35.4 2.9 4.1 5 0 0 5 5 5 1 Ring finger domain zf-C3HC4_2 PF13923.1 KLO12942.1 - 1.2e-07 31.5 3.3 1.2e-07 31.5 2.3 3.6 5 0 0 5 5 5 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KLO12942.1 - 3e-05 23.5 2.7 3e-05 23.5 1.9 3.6 5 1 0 5 5 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KLO12942.1 - 8e-05 22.2 3.7 8e-05 22.2 2.5 4.3 5 1 1 6 6 6 1 zinc-RING finger domain zf-rbx1 PF12678.2 KLO12942.1 - 0.0021 18.1 4.3 0.0021 18.1 2.9 3.4 3 1 0 3 3 3 1 RING-H2 zinc finger zf-RING_6 PF14835.1 KLO12942.1 - 0.02 14.6 0.3 0.099 12.4 0.2 2.2 1 1 0 1 1 1 0 zf-RING of BARD1-type protein Redoxin PF08534.5 KLO12942.1 - 0.03 13.8 0.0 0.068 12.7 0.0 1.6 1 0 0 1 1 1 0 Redoxin zf-RING_UBOX PF13445.1 KLO12942.1 - 0.06 13.0 2.2 0.21 11.3 1.5 2.0 1 0 0 1 1 1 0 RING-type zinc-finger zf-C2H2_4 PF13894.1 KLO12942.1 - 0.07 13.4 0.1 0.07 13.4 0.0 6.4 6 1 0 6 6 6 0 C2H2-type zinc finger zf-C2H2 PF00096.21 KLO12942.1 - 0.31 11.4 0.2 0.31 11.4 0.1 5.7 6 0 0 6 6 6 0 Zinc finger, C2H2 type FYVE PF01363.16 KLO12942.1 - 0.34 10.8 16.1 2.2 8.2 2.3 5.3 4 1 0 4 4 4 0 FYVE zinc finger zf-H2C2_5 PF13909.1 KLO12942.1 - 0.4 11.0 0.1 0.4 11.0 0.0 5.4 6 0 0 6 6 6 0 C2H2-type zinc-finger domain zf-met PF12874.2 KLO12942.1 - 0.71 10.1 33.7 0.2 11.8 1.0 5.5 6 0 0 6 6 6 0 Zinc-finger of C2H2 type zf-RING_4 PF14570.1 KLO12942.1 - 0.89 9.1 12.4 0.1 12.1 2.4 3.5 3 1 0 3 3 3 0 RING/Ubox like zinc-binding domain DUF629 PF04780.7 KLO12942.1 - 1.7 7.1 5.7 26 3.1 0.0 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF629) zf-C2H2_2 PF12756.2 KLO12942.1 - 2.6 8.1 19.8 0.97 9.5 0.8 4.4 4 2 1 5 5 5 0 C2H2 type zinc-finger (2 copies) zf-DHHC PF01529.15 KLO12942.1 - 3.4 7.0 12.4 0.6 9.4 0.4 3.2 3 0 0 3 3 3 0 DHHC palmitoyltransferase DUF4098 PF13345.1 KLO12944.1 - 0.00049 19.9 8.4 0.003 17.4 5.8 2.4 1 1 1 2 2 2 1 Domain of unknown function (DUF4098) F-box-like PF12937.2 KLO12945.1 - 6.6e-06 25.7 0.1 1.6e-05 24.5 0.1 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KLO12945.1 - 5.5e-05 22.7 1.0 0.21 11.2 0.1 2.9 2 0 0 2 2 2 2 F-box domain Ribosomal_L44 PF00935.14 KLO12946.1 - 3.9e-36 122.9 10.3 6.4e-36 122.2 7.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L44 Nodulin_late PF07127.6 KLO12946.1 - 0.018 15.1 0.3 0.036 14.1 0.2 1.5 1 0 0 1 1 1 0 Late nodulin protein zf-RING_2 PF13639.1 KLO12947.1 - 2.8e-09 36.6 3.3 2.8e-09 36.6 2.3 3.0 3 0 0 3 3 3 1 Ring finger domain zf-C3HC4 PF00097.20 KLO12947.1 - 8.4e-06 25.3 2.3 8.4e-06 25.3 1.6 3.8 5 0 0 5 5 5 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 KLO12947.1 - 2.5e-05 24.2 0.5 2.5e-05 24.2 0.3 2.8 3 1 0 3 3 2 1 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 KLO12947.1 - 4.6e-05 23.3 3.8 4.6e-05 23.3 2.6 3.9 4 1 0 4 4 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KLO12947.1 - 6.5e-05 22.5 2.1 6.5e-05 22.5 1.4 4.5 5 1 0 5 5 5 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 KLO12947.1 - 6.6e-05 22.4 1.8 6.6e-05 22.4 1.3 3.5 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 KLO12947.1 - 0.017 14.9 0.7 0.017 14.9 0.5 4.4 5 0 0 5 5 5 0 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 KLO12947.1 - 0.12 12.1 3.6 0.11 12.2 0.3 2.7 2 1 0 2 2 2 0 RING-type zinc-finger Rtf2 PF04641.7 KLO12947.1 - 0.13 11.4 2.2 0.19 10.9 0.3 2.1 2 0 0 2 2 2 0 Rtf2 RING-finger zf-C2H2_6 PF13912.1 KLO12947.1 - 0.22 11.4 0.2 0.22 11.4 0.1 5.6 8 0 0 8 8 8 0 C2H2-type zinc finger zf-C2H2_4 PF13894.1 KLO12947.1 - 0.29 11.5 22.1 0.23 11.8 0.4 6.3 7 0 0 7 7 7 0 C2H2-type zinc finger zf-Nse PF11789.3 KLO12947.1 - 0.41 10.1 3.5 0.33 10.4 0.8 2.2 2 1 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit zf-met PF12874.2 KLO12947.1 - 3 8.1 22.2 0.88 9.8 0.1 5.7 6 0 0 6 6 6 0 Zinc-finger of C2H2 type SDA1 PF05285.7 KLO12949.1 - 0.0085 15.4 1.7 0.0085 15.4 1.2 1.7 1 1 1 2 2 2 1 SDA1 zf-MYND PF01753.13 KLO12950.1 - 1e-08 34.8 20.8 1e-08 34.8 14.4 2.3 2 0 0 2 2 2 1 MYND finger PolC_DP2 PF03833.8 KLO12950.1 - 0.54 7.8 2.8 0.81 7.2 2.0 1.2 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 MutS_V PF00488.16 KLO12951.1 - 1.8e-97 325.3 0.1 2.8e-97 324.7 0.0 1.3 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 KLO12951.1 - 9.9e-34 116.9 0.6 2.7e-33 115.4 0.4 1.8 1 0 0 1 1 1 1 MutS domain III MutS_IV PF05190.13 KLO12951.1 - 7.1e-18 64.5 0.4 1.9e-17 63.2 0.3 1.8 1 0 0 1 1 1 1 MutS family domain IV MutS_II PF05188.12 KLO12951.1 - 1.6e-16 60.6 0.5 1.6e-16 60.6 0.3 2.5 3 0 0 3 3 3 1 MutS domain II MutS_I PF01624.15 KLO12951.1 - 3.1e-12 46.5 0.0 8.7e-12 45.0 0.0 1.8 1 0 0 1 1 1 1 MutS domain I AAA_23 PF13476.1 KLO12951.1 - 1.1 9.5 0.0 1.1 9.5 0.0 2.8 2 1 1 3 3 3 0 AAA domain Lipase_3 PF01764.20 KLO12952.1 - 9e-19 67.4 0.0 1.5e-18 66.7 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) NUFIP1 PF10453.4 KLO12952.1 - 0.027 13.9 0.3 0.067 12.7 0.1 1.7 1 1 0 1 1 1 0 Nuclear fragile X mental retardation-interacting protein 1 (NUFIP1) DUF3534 PF12053.3 KLO12952.1 - 0.028 14.2 0.0 0.056 13.3 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3534) Lipase_3 PF01764.20 KLO12953.1 - 5.2e-20 71.5 0.0 8.8e-20 70.7 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) PGAP1 PF07819.8 KLO12953.1 - 0.094 12.2 0.0 0.18 11.3 0.0 1.4 1 0 0 1 1 1 0 PGAP1-like protein Asp PF00026.18 KLO12954.1 - 1e-28 100.5 9.3 1.4e-27 96.8 6.5 2.0 1 1 0 1 1 1 1 Eukaryotic aspartyl protease Asp_protease_2 PF13650.1 KLO12954.1 - 8.2e-05 23.0 4.7 0.00095 19.6 1.8 2.6 2 0 0 2 2 2 1 Aspartyl protease Arylsulfotrans PF05935.6 KLO12955.1 - 0.091 11.2 0.0 0.14 10.6 0.0 1.2 1 0 0 1 1 1 0 Arylsulfotransferase (ASST) Kelch_3 PF13415.1 KLO12955.1 - 2.1 8.6 8.4 2.2 8.5 0.0 4.4 4 1 1 5 5 5 0 Galactose oxidase, central domain WAPL PF07814.8 KLO12956.1 - 3.7e-08 32.4 0.1 2.2e-06 26.6 0.0 2.3 2 0 0 2 2 2 2 Wings apart-like protein regulation of heterochromatin HAD_2 PF13419.1 KLO12957.1 - 9.8e-29 100.8 0.0 2.1e-28 99.7 0.0 1.6 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 KLO12957.1 - 0.00061 19.4 0.0 0.0012 18.4 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like Prenyltrans_2 PF13249.1 KLO12957.1 - 0.00087 19.6 0.0 2.3 8.6 0.0 2.6 2 0 0 2 2 2 2 Prenyltransferase-like Nuc_recep-AF1 PF11825.3 KLO12957.1 - 0.14 12.0 0.0 1.6 8.6 0.0 2.3 2 0 0 2 2 2 0 Nuclear/hormone receptor activator site AF-1 DUF826 PF05696.6 KLO12959.1 - 0.16 12.1 0.5 1.9 8.7 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF826) DUF1772 PF08592.6 KLO12960.1 - 6.8 6.4 11.9 0.44 10.2 2.0 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF1772) Zn_clus PF00172.13 KLO12962.1 - 5.1e-10 39.1 8.3 8.3e-10 38.4 5.7 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain F-box-like PF12937.2 KLO12963.1 - 0.0021 17.7 0.1 0.006 16.2 0.0 1.8 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.2 KLO12963.1 - 2.2 8.0 5.1 9 6.0 0.0 4.0 4 1 1 5 5 5 0 Leucine Rich repeats (2 copies) DUF3357 PF11837.3 KLO12964.1 - 0.12 12.2 0.0 0.37 10.6 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF3357) Abhydrolase_1 PF00561.15 KLO12965.1 - 0.054 13.0 0.0 0.073 12.6 0.0 1.1 1 0 0 1 1 1 0 alpha/beta hydrolase fold F-box-like PF12937.2 KLO12967.1 - 0.047 13.4 0.1 0.18 11.5 0.0 2.1 2 0 0 2 2 2 0 F-box-like F-box-like PF12937.2 KLO12970.1 - 0.0033 17.1 0.7 0.19 11.4 0.3 3.7 3 1 0 3 3 3 1 F-box-like LRR_8 PF13855.1 KLO12970.1 - 0.03 14.0 0.8 0.21 11.3 0.0 2.9 2 1 0 2 2 2 0 Leucine rich repeat LRR_4 PF12799.2 KLO12970.1 - 0.27 10.9 4.5 26 4.5 0.0 4.5 5 0 0 5 5 5 0 Leucine Rich repeats (2 copies) DUF4245 PF14030.1 KLO12971.1 - 0.011 15.5 0.1 0.018 14.7 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4245) LcrV PF04792.7 KLO12971.1 - 0.2 10.6 1.7 0.83 8.6 0.5 2.0 1 1 1 2 2 2 0 V antigen (LcrV) protein DSPc PF00782.15 KLO12976.1 - 4.6e-31 107.1 0.0 5.9e-31 106.8 0.0 1.1 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 KLO12976.1 - 1.5e-05 24.5 0.0 1.7e-05 24.2 0.0 1.1 1 0 0 1 1 1 1 Protein-tyrosine phosphatase CDKN3 PF05706.7 KLO12976.1 - 0.006 16.0 0.0 0.0095 15.3 0.0 1.3 1 0 0 1 1 1 1 Cyclin-dependent kinase inhibitor 3 (CDKN3) PTPlike_phytase PF14566.1 KLO12976.1 - 0.041 13.9 0.0 0.073 13.1 0.0 1.4 1 0 0 1 1 1 0 Inositol hexakisphosphate DUF4394 PF14339.1 KLO12976.1 - 0.077 12.2 0.0 0.1 11.8 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4394) F-box-like PF12937.2 KLO12979.1 - 0.01 15.5 2.0 0.033 13.9 1.4 1.9 1 0 0 1 1 1 0 F-box-like LRR_4 PF12799.2 KLO12979.1 - 0.067 12.8 0.0 2.3 7.9 0.0 3.3 3 0 0 3 3 3 0 Leucine Rich repeats (2 copies) F-box-like PF12937.2 KLO12980.1 - 1.4e-05 24.7 0.5 4.9e-05 22.9 0.3 2.0 1 0 0 1 1 1 1 F-box-like DUF746 PF05344.6 KLO12981.1 - 0.13 11.8 0.2 0.3 10.6 0.0 1.6 2 0 0 2 2 2 0 Domain of Unknown Function (DUF746) Transferase PF02458.10 KLO12983.1 - 2.4e-06 26.2 0.0 4.8e-06 25.2 0.0 1.4 2 0 0 2 2 2 1 Transferase family Condensation PF00668.15 KLO12983.1 - 7.5e-06 25.0 0.0 3e-05 23.0 0.0 1.8 2 0 0 2 2 2 1 Condensation domain Peptidase_M15_2 PF05951.8 KLO12983.1 - 0.0068 15.8 0.0 0.013 14.9 0.0 1.3 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF882) RIO1 PF01163.17 KLO12986.1 - 1.5e-72 242.9 0.0 1.5e-72 242.9 0.0 1.8 2 0 0 2 2 2 1 RIO1 family APH PF01636.18 KLO12986.1 - 4.6e-06 26.5 0.7 0.032 13.9 0.1 2.7 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.9 KLO12986.1 - 0.00033 19.7 0.5 0.0033 16.5 0.3 2.2 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.20 KLO12986.1 - 0.0023 17.1 0.0 0.0023 17.1 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain CDC45 PF02724.9 KLO12986.1 - 5 5.0 22.0 0.12 10.3 6.7 2.3 2 0 0 2 2 2 0 CDC45-like protein DUF975 PF06161.6 KLO12987.1 - 0.075 12.7 5.2 0.11 12.2 3.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF975) ILVD_EDD PF00920.16 KLO12991.1 - 8.7e-203 674.4 0.0 1.3e-202 673.8 0.0 1.3 1 0 0 1 1 1 1 Dehydratase family Methyltransf_11 PF08241.7 KLO12992.1 - 3.8e-12 46.5 0.0 6.5e-12 45.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KLO12992.1 - 2.1e-11 43.8 0.0 2.9e-11 43.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KLO12992.1 - 3.9e-09 36.2 0.0 1.2e-08 34.6 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KLO12992.1 - 3.8e-07 30.4 0.0 7.8e-07 29.4 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KLO12992.1 - 7.8e-07 28.4 0.0 2.6e-06 26.7 0.0 1.8 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.1 KLO12992.1 - 1.7e-06 28.3 0.0 3.1e-06 27.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KLO12992.1 - 7.2e-06 26.5 0.0 4.5e-05 23.9 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.10 KLO12992.1 - 6.8e-05 22.6 0.0 0.00012 21.7 0.0 1.4 1 1 0 1 1 1 1 Hypothetical methyltransferase Methyltransf_26 PF13659.1 KLO12992.1 - 0.012 15.6 0.0 0.027 14.4 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain FtsJ PF01728.14 KLO12992.1 - 0.056 13.4 0.0 0.1 12.5 0.0 1.5 1 1 0 1 1 1 0 FtsJ-like methyltransferase TPMT PF05724.6 KLO12992.1 - 0.15 11.4 0.0 0.27 10.6 0.0 1.4 1 0 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) p450 PF00067.17 KLO12993.1 - 1.1e-65 221.9 0.0 1.4e-65 221.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 UbiA PF01040.13 KLO12994.1 - 3.6e-22 78.8 7.0 4.7e-22 78.4 4.9 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family Methyltransf_2 PF00891.13 KLO12995.1 - 3.8e-30 104.8 0.0 5.9e-30 104.2 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase MTS PF05175.9 KLO12995.1 - 0.0012 18.2 0.0 0.011 15.1 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_12 PF08242.7 KLO12995.1 - 0.0025 18.2 0.0 0.0065 16.9 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KLO12995.1 - 0.0047 17.5 0.0 0.015 15.8 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_16 PF10294.4 KLO12995.1 - 0.0093 15.4 0.0 0.015 14.7 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase MarR_2 PF12802.2 KLO12995.1 - 0.01 15.4 0.0 0.027 14.1 0.0 1.7 1 0 0 1 1 1 0 MarR family Methyltransf_31 PF13847.1 KLO12995.1 - 0.053 13.1 0.0 0.15 11.6 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain RPA_C PF08784.6 KLO12995.1 - 0.14 12.5 0.0 0.48 10.8 0.0 1.8 1 1 0 1 1 1 0 Replication protein A C terminal p450 PF00067.17 KLO12996.1 - 9.7e-61 205.6 0.0 1.6e-60 204.9 0.0 1.3 1 1 0 1 1 1 1 Cytochrome P450 AMP-binding PF00501.23 KLO12999.1 - 5.7e-27 94.1 0.0 2.7e-24 85.3 0.0 2.0 2 0 0 2 2 2 2 AMP-binding enzyme PP-binding PF00550.20 KLO12999.1 - 5.5e-07 29.7 0.0 2.8e-06 27.4 0.0 2.1 2 0 0 2 2 2 1 Phosphopantetheine attachment site GRASP55_65 PF04495.9 KLO13000.1 - 4.2e-05 23.5 0.0 0.0001 22.3 0.0 1.7 1 1 0 1 1 1 1 GRASP55/65 PDZ-like domain PDZ_2 PF13180.1 KLO13000.1 - 9.1e-05 22.2 0.0 0.00016 21.4 0.0 1.4 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.19 KLO13000.1 - 0.013 15.7 0.0 0.023 14.8 0.0 1.5 1 0 0 1 1 1 0 PDZ domain (Also known as DHR or GLGF) Acyl-CoA_dh_1 PF00441.19 KLO13001.1 - 1e-19 71.1 0.6 4.5e-19 69.0 0.2 2.1 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 KLO13001.1 - 1.6e-09 37.1 0.0 3.9e-09 35.8 0.0 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.6 KLO13001.1 - 3.9e-07 30.3 0.0 8.7e-07 29.2 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Syntaxin_2 PF14523.1 KLO13003.1 - 3.5e-20 71.9 6.1 3.5e-20 71.9 4.2 3.2 2 1 1 3 3 3 1 Syntaxin-like protein SNARE PF05739.14 KLO13003.1 - 4.6e-19 67.8 7.6 5.4e-19 67.6 0.8 3.2 2 1 0 2 2 2 1 SNARE domain MCPsignal PF00015.16 KLO13003.1 - 0.0045 16.5 2.9 0.0045 16.5 2.0 2.4 1 1 1 2 2 2 1 Methyl-accepting chemotaxis protein (MCP) signalling domain Synaptobrevin PF00957.16 KLO13003.1 - 0.012 15.1 6.1 0.022 14.3 0.1 3.0 2 1 1 3 3 3 0 Synaptobrevin Med9 PF07544.8 KLO13003.1 - 0.091 12.5 3.1 2 8.2 0.2 2.8 2 1 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 ATP-synt_E PF05680.7 KLO13003.1 - 0.14 12.1 1.1 0.4 10.6 0.1 2.2 1 1 1 2 2 2 0 ATP synthase E chain DUF2746 PF10874.3 KLO13003.1 - 0.24 11.6 4.4 0.7 10.1 0.2 2.9 2 2 0 2 2 2 0 Protein of unknown function (DUF2746) TMPIT PF07851.8 KLO13003.1 - 0.55 9.2 4.5 4.8 6.1 0.1 2.1 1 1 2 3 3 3 0 TMPIT-like protein Reo_sigmaC PF04582.7 KLO13003.1 - 0.62 9.1 7.5 2.7 7.0 0.4 2.2 1 1 1 2 2 2 0 Reovirus sigma C capsid protein DUF3708 PF12501.3 KLO13003.1 - 0.75 9.6 5.6 0.6 9.9 0.7 2.5 1 1 2 3 3 3 0 Phosphate ATP-binding cassette transporter V-SNARE PF05008.10 KLO13003.1 - 8.8 6.5 9.0 1.4 9.1 1.1 3.0 2 1 1 3 3 3 0 Vesicle transport v-SNARE protein N-terminus DUF1664 PF07889.7 KLO13003.1 - 9.2 6.0 8.7 4.4 7.1 0.6 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) Pkinase PF00069.20 KLO13007.1 - 8.8e-72 241.3 0.0 1.1e-71 241.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KLO13007.1 - 3.2e-44 150.9 0.0 4e-44 150.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KLO13007.1 - 2.6e-09 36.4 0.0 2.1e-08 33.5 0.0 1.9 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 KLO13007.1 - 0.0082 15.2 0.0 0.014 14.4 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KLO13007.1 - 0.038 13.7 0.1 0.24 11.1 0.1 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.4 KLO13007.1 - 0.044 13.1 0.1 0.079 12.2 0.1 1.4 1 1 0 1 1 1 0 PhoP regulatory network protein YrbL RIO1 PF01163.17 KLO13007.1 - 0.1 11.9 0.1 0.54 9.5 0.0 2.0 2 1 1 3 3 3 0 RIO1 family Nop PF01798.13 KLO13008.1 - 7.7e-60 200.5 0.0 1.6e-59 199.4 0.0 1.6 1 0 0 1 1 1 1 Putative snoRNA binding domain NOSIC PF08060.8 KLO13008.1 - 8.2e-27 92.7 0.3 1.4e-26 91.9 0.2 1.4 1 0 0 1 1 1 1 NOSIC (NUC001) domain NOP5NT PF08156.8 KLO13008.1 - 1.4e-21 76.4 0.1 1.4e-21 76.4 0.1 2.8 2 1 1 3 3 3 1 NOP5NT (NUC127) domain DUF3246 PF11596.3 KLO13008.1 - 0.25 10.5 0.9 0.39 9.9 0.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3246) RR_TM4-6 PF06459.7 KLO13008.1 - 7.3 6.3 28.6 3.1 7.6 18.1 1.6 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 Na_H_Exchanger PF00999.16 KLO13009.1 - 7.6e-58 195.8 47.7 1.1e-57 195.3 33.1 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Trp_halogenase PF04820.9 KLO13011.1 - 1.5e-30 106.2 0.0 5.5e-16 58.2 0.0 2.2 1 1 1 2 2 2 2 Tryptophan halogenase FAD_binding_3 PF01494.14 KLO13011.1 - 3.6e-11 42.7 0.0 5.2e-09 35.6 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.1 KLO13011.1 - 2.9e-06 27.1 0.2 1.1e-05 25.4 0.1 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 KLO13011.1 - 7.9e-06 24.9 0.3 2.1e-05 23.6 0.1 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_oxidored PF12831.2 KLO13011.1 - 4.3e-05 22.7 0.2 9.6e-05 21.6 0.1 1.7 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 KLO13011.1 - 6.9e-05 22.8 0.0 0.00019 21.4 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 KLO13011.1 - 8.2e-05 21.2 0.0 0.00013 20.5 0.0 1.3 1 0 0 1 1 1 1 HI0933-like protein FAD_binding_2 PF00890.19 KLO13011.1 - 0.0001 21.2 0.1 0.00019 20.4 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain GIDA PF01134.17 KLO13011.1 - 0.00024 20.0 0.1 0.00055 18.8 0.1 1.5 2 0 0 2 2 2 1 Glucose inhibited division protein A Pyr_redox PF00070.22 KLO13011.1 - 0.006 16.9 0.1 0.016 15.5 0.0 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 KLO13011.1 - 0.016 14.3 0.0 0.034 13.2 0.0 1.4 1 0 0 1 1 1 0 Thi4 family ApbA PF02558.11 KLO13011.1 - 0.065 12.6 0.1 0.13 11.7 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA ThiF PF00899.16 KLO13011.1 - 0.072 12.9 0.9 0.19 11.5 0.1 2.0 2 0 0 2 2 2 0 ThiF family TFIIS_C PF01096.13 KLO13012.1 - 2.2e-21 75.1 6.0 2.2e-21 75.1 4.1 2.9 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.11 KLO13012.1 - 1.1e-07 31.3 2.0 1.1e-07 31.3 1.4 2.9 3 0 0 3 3 3 1 RNA polymerases M/15 Kd subunit Zn_Tnp_IS1595 PF12760.2 KLO13012.1 - 9.6e-07 28.5 10.6 8.7e-05 22.2 0.6 2.3 2 0 0 2 2 2 2 Transposase zinc-ribbon domain Terminase_GpA PF05876.7 KLO13012.1 - 0.016 13.6 1.5 0.016 13.6 1.1 1.9 1 1 1 2 2 2 0 Phage terminase large subunit (GpA) zf-DNA_Pol PF08996.5 KLO13012.1 - 0.025 13.9 0.8 0.025 13.9 0.6 2.2 1 1 1 2 2 2 0 DNA Polymerase alpha zinc finger PhnA_Zn_Ribbon PF08274.7 KLO13012.1 - 0.025 14.3 10.8 0.026 14.3 0.1 3.1 2 1 0 2 2 2 0 PhnA Zinc-Ribbon DUF2387 PF09526.5 KLO13012.1 - 0.043 13.7 7.8 1.5 8.8 1.5 2.3 1 1 1 2 2 2 0 Probable metal-binding protein (DUF2387) Lar_restr_allev PF14354.1 KLO13012.1 - 0.12 12.6 5.5 1.7 9.0 0.2 2.3 2 0 0 2 2 2 0 Restriction alleviation protein Lar PHD PF00628.24 KLO13012.1 - 0.48 10.1 14.3 0.4 10.4 0.8 3.0 2 2 0 2 2 2 0 PHD-finger Opy2 PF09463.5 KLO13012.1 - 1.3 9.2 0.1 1.3 9.2 0.1 3.8 3 1 0 3 3 2 0 Opy2 protein Zn-ribbon_8 PF09723.5 KLO13012.1 - 1.4 8.9 11.5 2.3 8.2 0.1 4.0 4 0 0 4 4 4 0 Zinc ribbon domain ZZ PF00569.12 KLO13012.1 - 2.2 7.8 10.7 35 4.0 0.1 3.9 4 0 0 4 4 4 0 Zinc finger, ZZ type C1_4 PF07975.7 KLO13012.1 - 2.5 8.1 14.2 2.5 8.1 0.2 3.4 1 1 2 3 3 3 0 TFIIH C1-like domain C1_1 PF00130.17 KLO13012.1 - 2.6 7.8 11.5 0.71 9.6 2.1 2.6 2 1 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Zn_Tnp_IS1 PF03811.8 KLO13012.1 - 2.6 7.5 16.9 3.5 7.2 0.1 3.8 3 1 0 3 3 3 0 InsA N-terminal domain zf-C3HC4_4 PF15227.1 KLO13012.1 - 3.3 7.6 10.9 24 4.8 0.1 3.3 3 0 0 3 3 3 0 zinc finger of C3HC4-type, RING Rep_fac-A_C PF08646.5 KLO13012.1 - 3.9 7.1 12.1 0.75 9.4 0.9 2.7 1 1 1 2 2 2 0 Replication factor-A C terminal domain Cys_rich_KTR PF14205.1 KLO13012.1 - 4.4 6.8 9.4 6.6 6.2 0.3 3.3 3 1 0 3 3 3 0 Cysteine-rich KTR OrfB_Zn_ribbon PF07282.6 KLO13012.1 - 5.2 6.7 12.5 4.5 7.0 1.8 2.5 2 1 0 2 2 2 0 Putative transposase DNA-binding domain zinc-ribbons_6 PF07191.7 KLO13012.1 - 6.4 6.6 11.7 3.7 7.4 1.2 2.7 2 1 0 2 2 2 0 zinc-ribbons zf-CHY PF05495.7 KLO13012.1 - 8.6 6.5 12.9 4.3e+03 -2.1 9.0 2.6 1 1 0 1 1 1 0 CHY zinc finger HypA PF01155.14 KLO13012.1 - 9.6 5.9 10.5 82 2.9 7.3 2.4 1 1 0 1 1 1 0 Hydrogenase expression/synthesis hypA family zf-RING_2 PF13639.1 KLO13013.1 - 0.00063 19.5 0.2 0.0013 18.5 0.1 1.6 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 KLO13013.1 - 0.52 10.4 3.3 3.3 7.8 2.5 2.0 1 1 1 2 2 2 0 RING-H2 zinc finger He_PIG_assoc PF10632.4 KLO13016.1 - 0.49 9.7 3.4 1 8.7 2.3 1.5 1 0 0 1 1 1 0 He_PIG associated, NEW1 domain of bacterial glycohydrolase Terpene_synth_C PF03936.11 KLO13018.1 - 5.7e-07 29.0 0.0 7.1e-07 28.7 0.0 1.2 1 0 0 1 1 1 1 Terpene synthase family, metal binding domain p450 PF00067.17 KLO13021.1 - 3.1e-66 223.8 0.6 6.1e-65 219.5 0.4 2.5 1 1 0 1 1 1 1 Cytochrome P450 Cupin_1 PF00190.17 KLO13022.1 - 1.5e-26 92.5 0.1 1.3e-12 47.4 0.0 2.2 2 0 0 2 2 2 2 Cupin Cupin_2 PF07883.6 KLO13022.1 - 2.7e-26 90.8 0.2 7.6e-12 44.5 0.0 2.3 2 0 0 2 2 2 2 Cupin domain Cupin_3 PF05899.7 KLO13022.1 - 1.1e-10 40.6 0.1 0.00014 21.1 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF861) GPI PF06560.6 KLO13022.1 - 0.00011 21.3 0.0 0.00017 20.6 0.0 1.2 1 0 0 1 1 1 1 Glucose-6-phosphate isomerase (GPI) MannoseP_isomer PF01050.13 KLO13022.1 - 0.00011 21.7 0.0 0.074 12.6 0.0 2.2 2 0 0 2 2 2 2 Mannose-6-phosphate isomerase AraC_binding PF02311.14 KLO13022.1 - 0.00023 20.8 0.1 0.097 12.3 0.0 2.4 2 0 0 2 2 2 2 AraC-like ligand binding domain ARD PF03079.9 KLO13022.1 - 0.00037 20.4 0.0 0.0033 17.4 0.0 2.0 2 0 0 2 2 2 1 ARD/ARD' family FdtA PF05523.6 KLO13022.1 - 0.0015 18.0 0.0 0.088 12.3 0.0 2.2 2 0 0 2 2 2 1 WxcM-like, C-terminal 3-HAO PF06052.7 KLO13022.1 - 0.0049 16.2 0.0 0.26 10.7 0.0 2.3 2 0 0 2 2 2 1 3-hydroxyanthranilic acid dioxygenase Cupin_4 PF08007.7 KLO13022.1 - 0.0099 15.1 0.0 0.45 9.7 0.0 2.2 2 0 0 2 2 2 1 Cupin superfamily protein cNMP_binding PF00027.24 KLO13022.1 - 0.12 12.1 0.0 0.25 11.1 0.0 1.5 1 0 0 1 1 1 0 Cyclic nucleotide-binding domain Dak1 PF02733.12 KLO13023.1 - 8.9e-92 307.1 0.0 1.2e-91 306.6 0.0 1.1 1 0 0 1 1 1 1 Dak1 domain Dak2 PF02734.12 KLO13023.1 - 7.3e-42 142.9 0.0 1.2e-41 142.2 0.0 1.4 1 0 0 1 1 1 1 DAK2 domain zf-H2C2_2 PF13465.1 KLO13025.1 - 4.3e-07 29.8 14.0 4.8e-07 29.7 0.3 4.3 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 KLO13025.1 - 1.1e-06 28.5 20.9 0.00022 21.3 2.4 3.9 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2 PF00096.21 KLO13025.1 - 4.1e-06 26.8 18.3 0.00053 20.1 2.0 3.4 3 0 0 3 3 3 2 Zinc finger, C2H2 type Zn_clus PF00172.13 KLO13025.1 - 0.00021 21.1 6.0 0.00039 20.2 4.2 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-met PF12874.2 KLO13025.1 - 0.00069 19.7 1.9 0.0012 18.9 0.3 2.2 2 0 0 2 2 2 1 Zinc-finger of C2H2 type Zn_Tnp_IS1 PF03811.8 KLO13025.1 - 0.03 13.8 7.0 0.094 12.2 4.8 1.9 1 0 0 1 1 1 0 InsA N-terminal domain zf-C2H2_2 PF12756.2 KLO13025.1 - 0.19 11.8 4.2 1.1 9.4 0.4 2.5 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) Uricase PF01014.13 KLO13026.1 - 5.8e-59 198.1 0.0 5.8e-32 110.6 0.0 2.1 2 0 0 2 2 2 2 Uricase DUF2066 PF09839.4 KLO13026.1 - 0.12 11.4 0.1 0.19 10.8 0.1 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2066) Glyoxalase PF00903.20 KLO13028.1 - 5.4e-25 87.8 0.1 6.7e-25 87.5 0.1 1.1 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.2 KLO13028.1 - 3.8e-18 66.0 0.0 4.8e-18 65.7 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase_4 PF13669.1 KLO13028.1 - 3.4e-09 36.6 0.0 4.8e-09 36.1 0.0 1.3 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_3 PF13468.1 KLO13028.1 - 0.00084 19.2 0.0 0.0011 18.8 0.0 1.2 1 0 0 1 1 1 1 Glyoxalase-like domain ATP-synt_G PF04718.10 KLO13029.1 - 3.7e-18 66.0 0.7 1.1e-17 64.5 0.1 1.9 2 0 0 2 2 2 1 Mitochondrial ATP synthase g subunit MT0933_antitox PF14013.1 KLO13029.1 - 0.039 14.0 1.0 0.066 13.3 0.7 1.3 1 0 0 1 1 1 0 MT0933-like antitoxin protein Pho88 PF10032.4 KLO13030.1 - 8.7e-73 243.6 0.0 9.6e-73 243.4 0.0 1.0 1 0 0 1 1 1 1 Phosphate transport (Pho88) PH PF00169.24 KLO13031.1 - 1.5e-09 37.9 0.0 2.6e-09 37.1 0.0 1.4 1 0 0 1 1 1 1 PH domain Carbpep_Y_N PF05388.6 KLO13031.1 - 0.031 14.4 2.5 2.7 8.1 0.8 2.5 2 0 0 2 2 2 0 Carboxypeptidase Y pro-peptide ApoLp-III PF07464.6 KLO13031.1 - 0.034 14.1 0.7 0.034 14.1 0.5 2.3 2 0 0 2 2 2 0 Apolipophorin-III precursor (apoLp-III) PH_11 PF15413.1 KLO13031.1 - 0.059 13.6 0.0 0.24 11.6 0.0 2.1 1 1 0 1 1 1 0 Pleckstrin homology domain DUF913 PF06025.7 KLO13031.1 - 0.062 12.0 3.4 0.046 12.4 1.0 1.7 2 0 0 2 2 2 0 Domain of Unknown Function (DUF913) BAR_2 PF10455.4 KLO13031.1 - 0.15 10.9 2.7 0.25 10.2 1.3 1.8 2 0 0 2 2 2 0 Bin/amphiphysin/Rvs domain for vesicular trafficking Glyco_hydro_28 PF00295.12 KLO13032.1 - 6.6e-22 77.8 3.8 9.7e-22 77.3 2.7 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 DUF410 PF04190.8 KLO13033.1 - 4.1e-33 115.0 0.0 5e-33 114.7 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF410) Steroid_dh PF02544.11 KLO13034.1 - 1e-33 116.2 5.1 1e-33 116.2 3.5 1.5 2 0 0 2 2 2 1 3-oxo-5-alpha-steroid 4-dehydrogenase ubiquitin PF00240.18 KLO13034.1 - 9.2e-07 28.1 0.1 1.7e-06 27.3 0.1 1.3 1 0 0 1 1 1 1 Ubiquitin family UAE_UbL PF14732.1 KLO13034.1 - 0.012 15.7 0.0 0.022 14.8 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin/SUMO-activating enzyme ubiquitin-like domain Ubiquitin_2 PF14560.1 KLO13034.1 - 0.013 15.7 0.1 0.034 14.3 0.0 1.7 1 1 0 1 1 1 0 Ubiquitin-like domain DUF1295 PF06966.7 KLO13034.1 - 0.026 13.8 0.3 0.046 13.0 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1295) YukD PF08817.5 KLO13034.1 - 0.14 12.6 0.0 0.24 11.9 0.0 1.3 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukD Abhydrolase_6 PF12697.2 KLO13035.1 - 2e-31 109.6 0.0 3e-31 109.0 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KLO13035.1 - 3e-16 59.4 0.0 5.3e-16 58.6 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KLO13035.1 - 2.9e-13 49.9 0.2 3.9e-11 42.9 0.1 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold PGAP1 PF07819.8 KLO13035.1 - 1.2e-09 38.1 0.0 1.6e-09 37.6 0.0 1.2 1 0 0 1 1 1 1 PGAP1-like protein Thioesterase PF00975.15 KLO13035.1 - 1e-08 35.7 0.0 1.4e-08 35.2 0.0 1.3 1 0 0 1 1 1 1 Thioesterase domain Hydrolase_4 PF12146.3 KLO13035.1 - 0.00024 20.8 0.0 0.00054 19.7 0.0 1.6 1 0 0 1 1 1 1 Putative lysophospholipase DUF676 PF05057.9 KLO13035.1 - 0.00029 20.2 0.0 0.00045 19.5 0.0 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Chlorophyllase2 PF12740.2 KLO13035.1 - 0.0029 16.5 0.0 0.006 15.4 0.0 1.6 1 1 0 1 1 1 1 Chlorophyllase enzyme Abhydrolase_3 PF07859.8 KLO13035.1 - 0.0099 15.4 0.0 0.016 14.8 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold PMM PF03332.8 KLO13035.1 - 0.024 14.2 0.0 0.034 13.7 0.0 1.3 1 0 0 1 1 1 0 Eukaryotic phosphomannomutase Chlorophyllase PF07224.6 KLO13035.1 - 0.026 13.3 0.0 0.042 12.6 0.0 1.3 1 0 0 1 1 1 0 Chlorophyllase Esterase PF00756.15 KLO13035.1 - 0.043 13.2 0.0 0.23 10.8 0.0 1.9 2 0 0 2 2 2 0 Putative esterase DUF900 PF05990.7 KLO13035.1 - 0.072 12.3 0.0 0.11 11.7 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) Lipase_3 PF01764.20 KLO13035.1 - 0.1 12.2 0.0 0.17 11.5 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) UvsW PF11637.3 KLO13035.1 - 0.13 11.9 0.2 0.26 10.9 0.2 1.4 1 0 0 1 1 1 0 ATP-dependant DNA helicase UvsW Arv1 PF04161.8 KLO13036.1 - 1.4e-27 96.9 0.0 2e-27 96.4 0.0 1.1 1 0 0 1 1 1 1 Arv1-like family Terpene_synth_C PF03936.11 KLO13037.1 - 8.7e-07 28.4 0.0 1.3e-06 27.8 0.0 1.4 1 1 0 1 1 1 1 Terpene synthase family, metal binding domain TRI5 PF06330.6 KLO13037.1 - 0.031 12.9 0.0 0.052 12.1 0.0 1.3 1 0 0 1 1 1 0 Trichodiene synthase (TRI5) Terpene_synth_C PF03936.11 KLO13038.1 - 2.5e-10 40.0 0.0 3.3e-10 39.6 0.0 1.3 1 0 0 1 1 1 1 Terpene synthase family, metal binding domain Terpene_synth_C PF03936.11 KLO13039.1 - 3e-11 43.0 0.0 3.9e-11 42.7 0.0 1.2 1 0 0 1 1 1 1 Terpene synthase family, metal binding domain DUF3334 PF11813.3 KLO13039.1 - 0.069 12.6 0.1 0.13 11.7 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3334) Terpene_synth_C PF03936.11 KLO13041.1 - 2.6e-08 33.4 0.0 3.6e-08 32.9 0.0 1.3 1 0 0 1 1 1 1 Terpene synthase family, metal binding domain Terpene_synth_C PF03936.11 KLO13042.1 - 7.6e-08 31.9 0.0 9.3e-08 31.6 0.0 1.2 1 0 0 1 1 1 1 Terpene synthase family, metal binding domain TAP42 PF04177.7 KLO13042.1 - 0.1 11.5 0.0 0.14 11.0 0.0 1.1 1 0 0 1 1 1 0 TAP42-like family Terpene_synth_C PF03936.11 KLO13043.1 - 8.6e-12 44.8 0.0 1.1e-11 44.5 0.0 1.1 1 0 0 1 1 1 1 Terpene synthase family, metal binding domain ThuA PF06283.6 KLO13044.1 - 4.1e-56 190.1 0.2 4.9e-56 189.8 0.1 1.1 1 0 0 1 1 1 1 Trehalose utilisation DDOST_48kD PF03345.9 KLO13044.1 - 0.04 12.4 0.0 0.051 12.1 0.0 1.2 1 0 0 1 1 1 0 Oligosaccharyltransferase 48 kDa subunit beta DUF2215 PF10225.4 KLO13044.1 - 0.12 11.8 0.1 0.19 11.1 0.1 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2215) zf-HIT PF04438.11 KLO13045.1 - 1.4e-06 27.8 10.0 2.2e-06 27.1 6.9 1.4 1 0 0 1 1 1 1 HIT zinc finger EBP50_C-term PF09007.6 KLO13045.1 - 0.11 12.3 0.4 0.23 11.3 0.3 1.5 1 0 0 1 1 1 0 EBP50, C-terminal PolC_DP2 PF03833.8 KLO13045.1 - 0.52 7.9 4.1 0.75 7.3 2.9 1.1 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 WD40 PF00400.27 KLO13046.1 - 9.5e-22 76.0 0.0 2.9e-05 23.7 0.0 5.5 5 0 0 5 5 5 5 WD domain, G-beta repeat Nucleoporin_N PF08801.6 KLO13046.1 - 0.019 13.7 0.0 0.56 8.8 0.0 2.7 2 1 1 3 3 3 0 Nup133 N terminal like PD40 PF07676.7 KLO13046.1 - 0.068 12.8 0.1 22 4.8 0.0 3.9 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat Coatomer_WDAD PF04053.9 KLO13046.1 - 0.16 10.7 0.0 0.49 9.1 0.0 1.7 2 0 0 2 2 2 0 Coatomer WD associated region RNA_pol_Rpb5_C PF01191.14 KLO13047.1 - 6.8e-33 112.0 0.2 1.4e-32 111.0 0.0 1.5 2 0 0 2 2 2 1 RNA polymerase Rpb5, C-terminal domain RNA_pol_Rpb5_N PF03871.9 KLO13047.1 - 9.2e-30 102.9 0.0 1.6e-29 102.1 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb5, N-terminal domain Mrr_cat PF04471.7 KLO13047.1 - 0.0065 16.2 0.0 0.01 15.6 0.0 1.4 1 1 0 1 1 1 1 Restriction endonuclease DnaJ PF00226.26 KLO13048.1 - 1.9e-26 91.5 0.9 3.1e-26 90.8 0.6 1.4 1 0 0 1 1 1 1 DnaJ domain CTDII PF01556.13 KLO13048.1 - 3.8e-23 81.1 1.4 1.4e-19 69.7 0.0 2.7 3 0 0 3 3 3 2 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.14 KLO13048.1 - 3.7e-14 52.5 17.1 6.2e-14 51.7 11.9 1.4 1 0 0 1 1 1 1 DnaJ central domain HypA PF01155.14 KLO13048.1 - 0.0079 15.8 6.7 0.26 10.9 1.4 2.3 2 0 0 2 2 2 2 Hydrogenase expression/synthesis hypA family RPT PF13446.1 KLO13048.1 - 0.13 11.7 0.0 0.29 10.5 0.0 1.5 1 0 0 1 1 1 0 A repeated domain in UCH-protein Cytochrom_c3_2 PF14537.1 KLO13048.1 - 0.26 11.6 5.0 0.67 10.3 3.3 1.9 1 1 0 1 1 1 0 Cytochrome c3 zf-RING_3 PF14369.1 KLO13048.1 - 3.6 7.6 7.7 53 3.9 0.2 3.8 2 1 1 3 3 3 0 zinc-finger A2L_zn_ribbon PF08792.5 KLO13048.1 - 7.2 6.1 17.0 5.8 6.5 0.6 4.1 3 1 0 3 3 3 0 A2L zinc ribbon domain Nol1_Nop2_Fmu PF01189.12 KLO13049.1 - 4.9e-20 72.0 0.0 2.4e-19 69.7 0.0 2.0 2 1 0 2 2 2 1 NOL1/NOP2/sun family zf-CCHC PF00098.18 KLO13050.1 - 1.1e-10 40.8 8.1 7.5e-05 22.4 1.4 2.4 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_3 PF13917.1 KLO13050.1 - 1.2e-07 31.3 7.7 0.00012 21.7 2.6 2.5 1 1 1 2 2 2 2 Zinc knuckle KH_1 PF00013.24 KLO13050.1 - 0.00021 20.8 0.0 0.00036 20.1 0.0 1.4 1 0 0 1 1 1 1 KH domain zf-CCHC_6 PF15288.1 KLO13050.1 - 0.00031 20.3 5.4 0.12 12.0 0.3 2.5 1 1 1 2 2 2 2 Zinc knuckle KH_3 PF13014.1 KLO13050.1 - 0.00047 19.7 0.0 0.00099 18.7 0.0 1.6 1 0 0 1 1 1 1 KH domain zf-CCHC_4 PF14392.1 KLO13050.1 - 0.0036 16.9 6.5 0.3 10.7 0.4 2.4 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_2 PF13696.1 KLO13050.1 - 0.11 12.0 0.1 0.11 12.0 0.1 3.3 3 1 1 4 4 4 0 Zinc knuckle NOB1_Zn_bind PF08772.6 KLO13050.1 - 0.21 11.4 3.4 1.9 8.3 0.5 2.4 1 1 1 2 2 2 0 Nin one binding (NOB1) Zn-ribbon like CCDC-167 PF15188.1 KLO13050.1 - 0.49 10.3 3.1 2.1 8.3 0.1 2.7 3 0 0 3 3 3 0 Coiled-coil domain-containing protein 167 Zn_ribbon_2 PF12674.2 KLO13050.1 - 0.91 9.9 4.6 1 9.7 1.7 2.1 2 0 0 2 2 2 0 Putative zinc ribbon domain bZIP_1 PF00170.16 KLO13051.1 - 7.3e-05 22.6 10.0 0.00014 21.7 6.9 1.5 1 1 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 KLO13051.1 - 0.00013 21.7 2.9 0.00013 21.7 2.0 1.6 2 0 0 2 2 2 1 Basic region leucine zipper Shugoshin_N PF07558.6 KLO13051.1 - 0.0021 17.7 0.9 0.0029 17.2 0.6 1.3 1 0 0 1 1 1 1 Shugoshin N-terminal coiled-coil region HAP1_N PF04849.8 KLO13051.1 - 0.023 13.6 1.0 0.025 13.5 0.7 1.0 1 0 0 1 1 1 0 HAP1 N-terminal conserved region CagA PF03507.8 KLO13051.1 - 0.025 14.4 0.0 0.027 14.3 0.0 1.0 1 0 0 1 1 1 0 CagA exotoxin TSC22 PF01166.13 KLO13051.1 - 0.038 13.9 0.2 0.053 13.4 0.2 1.2 1 0 0 1 1 1 0 TSC-22/dip/bun family Cactin_mid PF10312.4 KLO13051.1 - 0.057 12.6 0.1 0.061 12.5 0.1 1.0 1 0 0 1 1 1 0 Conserved mid region of cactin BcsB PF03170.8 KLO13051.1 - 0.065 11.2 0.6 0.071 11.1 0.4 1.0 1 0 0 1 1 1 0 Bacterial cellulose synthase subunit Metal_resist PF13801.1 KLO13051.1 - 0.077 12.9 1.9 0.091 12.7 1.3 1.2 1 0 0 1 1 1 0 Heavy-metal resistance Gal4_dimer PF03902.8 KLO13051.1 - 0.095 12.6 1.8 0.14 12.1 1.2 1.3 1 0 0 1 1 1 0 Gal4-like dimerisation domain BMFP PF04380.8 KLO13051.1 - 0.11 12.7 3.5 0.15 12.1 2.4 1.2 1 0 0 1 1 1 0 Membrane fusogenic activity M PF02370.11 KLO13051.1 - 0.15 12.5 3.7 0.25 11.7 2.6 1.3 1 0 0 1 1 1 0 M protein repeat WD40_alt PF14077.1 KLO13051.1 - 0.21 11.2 1.9 0.32 10.6 1.3 1.3 1 0 0 1 1 1 0 Alternative WD40 repeat motif UDG PF03167.14 KLO13052.1 - 5.2e-22 77.9 0.1 6.4e-12 45.1 0.0 2.3 2 0 0 2 2 2 2 Uracil DNA glycosylase superfamily CTP_transf_1 PF01148.15 KLO13053.1 - 3.9e-08 33.2 10.0 3.9e-08 33.2 6.9 3.7 2 2 0 2 2 2 1 Cytidylyltransferase family ADH_N PF08240.7 KLO13054.1 - 1.5e-25 89.0 4.1 2.7e-25 88.2 2.8 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KLO13054.1 - 1.4e-24 86.0 0.4 2.5e-24 85.2 0.3 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 KLO13054.1 - 0.018 15.9 0.0 0.039 14.8 0.0 1.6 1 0 0 1 1 1 0 Zinc-binding dehydrogenase SH2_2 PF14633.1 KLO13054.1 - 0.025 13.6 0.0 0.042 12.9 0.0 1.2 1 0 0 1 1 1 0 SH2 domain Cys_Met_Meta_PP PF01053.15 KLO13056.1 - 4.4e-128 426.8 0.0 5.8e-128 426.4 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme GHMP_kinases_N PF00288.21 KLO13056.1 - 8e-14 51.4 3.7 9.3e-13 48.0 2.2 3.2 3 1 0 3 3 3 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.8 KLO13056.1 - 2.7e-08 33.8 0.9 7.9e-07 29.1 0.1 2.7 1 1 1 2 2 2 1 GHMP kinases C terminal Met_gamma_lyase PF06838.6 KLO13056.1 - 0.00026 19.4 0.0 0.00061 18.1 0.0 1.5 1 1 0 1 1 1 1 Methionine gamma-lyase Beta_elim_lyase PF01212.16 KLO13056.1 - 0.00055 19.1 0.0 0.00093 18.4 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase GalKase_gal_bdg PF10509.4 KLO13056.1 - 0.00059 19.0 0.0 0.0013 18.0 0.0 1.5 1 0 0 1 1 1 1 Galactokinase galactose-binding signature Aminotran_1_2 PF00155.16 KLO13056.1 - 0.0014 17.6 0.0 0.0022 16.9 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II SelA PF03841.8 KLO13056.1 - 0.0062 15.3 0.0 0.016 13.9 0.0 1.6 1 1 0 1 1 1 1 L-seryl-tRNA selenium transferase DegT_DnrJ_EryC1 PF01041.12 KLO13056.1 - 0.0078 15.2 0.0 0.015 14.3 0.0 1.4 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family GDC-P PF02347.11 KLO13056.1 - 0.053 12.1 0.0 0.084 11.5 0.0 1.2 1 0 0 1 1 1 0 Glycine cleavage system P-protein Dioxygenase_C PF00775.16 KLO13057.1 - 5.8e-21 74.5 0.0 1.1e-20 73.6 0.0 1.4 1 1 0 1 1 1 1 Dioxygenase DUF4198 PF10670.4 KLO13057.1 - 0.13 12.2 0.0 0.21 11.5 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4198) F-box-like PF12937.2 KLO13058.1 - 0.1 12.3 2.9 0.11 12.1 0.0 2.5 2 1 0 2 2 2 0 F-box-like F-box PF00646.28 KLO13058.1 - 0.75 9.5 10.5 0.098 12.3 1.0 3.3 2 1 0 2 2 2 0 F-box domain F-box PF00646.28 KLO13059.1 - 0.035 13.7 0.3 0.19 11.4 0.2 2.3 1 1 0 1 1 1 0 F-box domain Telomere_Sde2 PF13019.1 KLO13060.1 - 3.1e-48 163.5 0.0 5e-48 162.8 0.0 1.3 1 0 0 1 1 1 1 Telomere stability and silencing DUF1295 PF06966.7 KLO13061.1 - 7.1e-37 126.9 6.4 5.2e-36 124.1 4.5 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF1295) zf-C2H2_4 PF13894.1 KLO13062.1 - 0.0013 18.8 16.5 0.098 13.0 0.4 3.7 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2 PF00096.21 KLO13062.1 - 0.0018 18.5 18.7 0.012 15.9 0.8 3.7 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.3 KLO13062.1 - 0.23 11.6 3.1 0.16 12.1 0.3 2.0 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 KLO13062.1 - 0.42 10.5 5.6 1.3 8.9 0.4 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger IMS PF00817.15 KLO13063.1 - 6.9e-37 126.5 0.0 1.3e-36 125.6 0.0 1.5 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.3 KLO13063.1 - 8.2e-14 51.6 0.0 2.6e-13 50.0 0.0 1.9 2 0 0 2 2 2 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.3 KLO13063.1 - 0.00059 19.7 0.0 0.0017 18.2 0.0 1.8 1 0 0 1 1 1 1 IMS family HHH motif DUF1651 PF07864.6 KLO13063.1 - 0.054 13.6 0.0 0.18 11.9 0.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF1651) Git3_C PF11970.3 KLO13065.1 - 0.0069 16.1 1.6 0.47 10.2 0.1 2.8 2 1 0 2 2 2 2 G protein-coupled glucose receptor regulating Gpa2 C-term CIA30 PF08547.7 KLO13066.1 - 4.7e-22 78.5 0.0 5.9e-22 78.2 0.0 1.1 1 0 0 1 1 1 1 Complex I intermediate-associated protein 30 (CIA30) GXGXG PF01493.14 KLO13066.1 - 0.055 12.4 0.0 0.18 10.7 0.0 1.8 1 1 1 2 2 2 0 GXGXG motif Ras PF00071.17 KLO13067.1 - 2.6e-56 189.4 0.1 3e-56 189.2 0.1 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KLO13067.1 - 6.1e-20 71.9 0.1 9.5e-20 71.2 0.1 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KLO13067.1 - 7.3e-10 38.3 0.0 9.6e-10 37.9 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 KLO13067.1 - 1.2e-05 24.8 0.0 2.4e-05 23.8 0.0 1.5 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 KLO13067.1 - 0.0021 18.0 0.0 0.003 17.4 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase ATP_bind_1 PF03029.12 KLO13067.1 - 0.013 15.0 1.4 0.18 11.3 0.0 2.0 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein AAA_25 PF13481.1 KLO13067.1 - 0.049 13.0 0.0 0.14 11.5 0.0 1.8 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.12 KLO13067.1 - 0.18 11.2 1.0 3.1 7.1 0.2 2.5 2 1 1 3 3 3 0 IstB-like ATP binding protein Pyr_redox_2 PF07992.9 KLO13068.1 - 7.4e-33 114.1 2.0 1.1e-32 113.6 1.4 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Rieske PF00355.21 KLO13068.1 - 3.2e-15 55.4 0.1 6.8e-15 54.4 0.0 1.5 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Pyr_redox_3 PF13738.1 KLO13068.1 - 2.3e-11 44.1 0.3 2.4e-06 27.7 0.0 2.9 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 KLO13068.1 - 3.9e-10 39.9 6.9 1.9e-08 34.5 0.1 3.1 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Reductase_C PF14759.1 KLO13068.1 - 1.2e-07 31.9 0.0 2.6e-07 30.8 0.0 1.6 1 0 0 1 1 1 1 Reductase C-terminal Rieske_2 PF13806.1 KLO13068.1 - 1.5e-06 27.8 0.0 9.7e-06 25.2 0.0 2.3 2 0 0 2 2 2 1 Rieske-like [2Fe-2S] domain K_oxygenase PF13434.1 KLO13068.1 - 5.4e-06 25.5 0.1 0.021 13.7 0.0 2.3 1 1 1 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.19 KLO13068.1 - 0.013 14.4 3.6 8 5.2 0.0 3.2 2 1 1 3 3 3 0 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 KLO13068.1 - 0.027 14.2 0.2 1.1 9.0 0.0 2.9 3 0 0 3 3 3 0 FAD-NAD(P)-binding NAD_binding_7 PF13241.1 KLO13068.1 - 0.036 14.3 0.7 0.2 11.9 0.1 2.2 1 1 0 2 2 2 0 Putative NAD(P)-binding HI0933_like PF03486.9 KLO13068.1 - 0.058 11.8 0.9 19 3.5 0.0 3.0 3 0 0 3 3 3 0 HI0933-like protein DUF3499 PF12005.3 KLO13069.1 - 0.046 13.8 1.1 8.2 6.6 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3499) Pro_CA PF00484.14 KLO13070.1 - 1.1e-37 129.3 0.2 1.5e-18 67.2 0.1 2.2 2 0 0 2 2 2 2 Carbonic anhydrase RF-1 PF00472.15 KLO13071.1 - 6.8e-12 45.2 1.1 1.2e-11 44.4 0.8 1.4 1 0 0 1 1 1 1 RF-1 domain MRP-S28 PF10213.4 KLO13071.1 - 0.00068 19.7 0.4 0.0011 19.0 0.3 1.3 1 0 0 1 1 1 1 Mitochondrial ribosomal subunit protein AAA_2 PF07724.9 KLO13071.1 - 0.057 13.3 0.0 0.099 12.5 0.0 1.4 1 1 0 1 1 1 0 AAA domain (Cdc48 subfamily) DUF4456 PF14644.1 KLO13071.1 - 0.13 11.4 2.7 0.2 10.8 1.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4456) Fe-ADH PF00465.14 KLO13071.1 - 0.14 10.7 0.0 0.21 10.1 0.0 1.3 1 0 0 1 1 1 0 Iron-containing alcohol dehydrogenase HSBP1 PF06825.7 KLO13072.1 - 3.6e-12 45.6 2.5 4.6e-12 45.3 1.7 1.2 1 0 0 1 1 1 1 Heat shock factor binding protein 1 DUF2365 PF10157.4 KLO13072.1 - 0.0058 16.5 0.1 0.007 16.2 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2365) DUF2130 PF09903.4 KLO13072.1 - 0.0061 15.3 0.1 0.0073 15.0 0.1 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2130) PMC2NT PF08066.7 KLO13072.1 - 0.027 14.7 0.1 0.072 13.3 0.0 1.7 2 0 0 2 2 2 0 PMC2NT (NUC016) domain Baculo_PEP_C PF04513.7 KLO13072.1 - 0.075 12.8 0.3 0.088 12.6 0.2 1.2 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus BLOC1_2 PF10046.4 KLO13072.1 - 0.13 12.3 0.2 0.24 11.5 0.1 1.5 1 1 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 FlaC_arch PF05377.6 KLO13072.1 - 0.14 12.1 0.4 0.27 11.1 0.3 1.5 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) Herpes_capsid PF06112.6 KLO13072.1 - 0.4 10.7 4.7 0.59 10.1 3.3 1.2 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein CR6_interact PF10147.4 KLO13073.1 - 5.2e-05 22.6 2.6 5.2e-05 22.6 1.8 2.5 2 0 0 2 2 2 1 Growth arrest and DNA-damage-inducible proteins-interacting protein 1 DUF2514 PF10721.4 KLO13073.1 - 0.67 9.6 26.2 0.91 9.2 9.7 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2514) SPX PF03105.14 KLO13073.1 - 1.1 8.9 24.8 0.092 12.5 5.5 2.4 2 0 0 2 2 2 0 SPX domain Rax2 PF12768.2 KLO13074.1 - 0.0029 16.8 1.8 0.011 14.9 1.3 1.9 1 1 0 1 1 1 1 Cortical protein marker for cell polarity BatD PF13584.1 KLO13078.1 - 0.055 12.0 0.1 0.077 11.5 0.0 1.1 1 0 0 1 1 1 0 Oxygen tolerance SKG6 PF08693.5 KLO13078.1 - 0.18 11.1 0.0 0.18 11.1 0.0 3.0 3 0 0 3 3 3 0 Transmembrane alpha-helix domain VPEP PF07589.6 KLO13078.1 - 0.97 9.4 4.2 2.7 7.9 2.9 1.8 1 0 0 1 1 1 0 PEP-CTERM motif PepSY_TM_2 PF13703.1 KLO13079.1 - 0.037 14.2 0.0 0.34 11.1 0.0 2.4 3 0 0 3 3 3 0 PepSY-associated TM helix Alpha_GJ PF03229.8 KLO13080.1 - 0.013 15.8 1.6 0.025 14.9 1.1 1.4 1 0 0 1 1 1 0 Alphavirus glycoprotein J TMEM154 PF15102.1 KLO13080.1 - 0.063 12.9 0.2 0.12 12.0 0.1 1.4 1 0 0 1 1 1 0 TMEM154 protein family TIG PF01833.19 KLO13081.1 - 0.03 14.3 0.7 2.5 8.1 0.1 3.0 2 1 0 2 2 2 0 IPT/TIG domain TMEM154 PF15102.1 KLO13082.1 - 0.041 13.5 0.2 0.086 12.5 0.1 1.5 1 0 0 1 1 1 0 TMEM154 protein family Med25_SD1 PF11235.3 KLO13084.1 - 0.011 16.1 1.1 0.018 15.3 0.8 1.3 1 0 0 1 1 1 0 Mediator complex subunit 25 synapsin 1 PepSY_TM_2 PF13703.1 KLO13084.1 - 0.031 14.4 0.2 0.061 13.5 0.1 1.4 1 0 0 1 1 1 0 PepSY-associated TM helix DUF347 PF03988.7 KLO13084.1 - 0.062 13.1 0.3 0.16 11.9 0.2 1.6 1 0 0 1 1 1 0 Repeat of Unknown Function (DUF347) DUF1180 PF06679.7 KLO13084.1 - 0.47 10.3 1.7 1.7 8.4 0.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1180) Nitrate_red_gam PF02665.9 KLO13086.1 - 0.046 13.0 0.0 0.085 12.1 0.0 1.4 1 0 0 1 1 1 0 Nitrate reductase gamma subunit TMEM154 PF15102.1 KLO13087.1 - 0.01 15.5 0.0 0.018 14.7 0.0 1.4 1 0 0 1 1 1 0 TMEM154 protein family Glycophorin_A PF01102.13 KLO13087.1 - 0.044 13.5 0.0 0.079 12.7 0.0 1.5 1 0 0 1 1 1 0 Glycophorin A Herpes_gE PF02480.11 KLO13087.1 - 0.046 11.9 0.0 0.084 11.1 0.0 1.4 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E Protocadherin PF08374.6 KLO13087.1 - 0.068 12.8 0.0 0.1 12.2 0.0 1.3 1 0 0 1 1 1 0 Protocadherin Sarcoglycan_2 PF05510.8 KLO13087.1 - 0.08 11.2 0.0 0.4 8.9 0.0 1.9 2 0 0 2 2 2 0 Sarcoglycan alpha/epsilon EphA2_TM PF14575.1 KLO13087.1 - 0.085 13.2 0.0 0.18 12.2 0.0 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Nitrate_red_gam PF02665.9 KLO13088.1 - 0.011 15.0 0.0 0.021 14.1 0.0 1.4 1 0 0 1 1 1 0 Nitrate reductase gamma subunit Rhabdo_glycop PF00974.13 KLO13088.1 - 0.061 11.5 0.0 0.081 11.1 0.0 1.2 1 0 0 1 1 1 0 Rhabdovirus spike glycoprotein DUF1422 PF07226.6 KLO13088.1 - 0.061 13.0 0.1 0.21 11.2 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1422) F-box-like PF12937.2 KLO13090.1 - 1.4e-09 37.4 2.9 2.1e-09 36.9 0.2 2.5 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 KLO13090.1 - 0.0045 16.6 0.6 0.0045 16.6 0.4 2.6 2 0 0 2 2 2 1 F-box domain DUF3407 PF11887.3 KLO13090.1 - 0.013 14.7 0.0 0.023 13.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3407) GDPD PF03009.12 KLO13090.1 - 0.039 13.4 0.0 0.065 12.7 0.0 1.4 1 0 0 1 1 1 0 Glycerophosphoryl diester phosphodiesterase family Lzipper-MIP1 PF14389.1 KLO13090.1 - 0.071 13.2 0.2 0.21 11.7 0.1 1.8 1 0 0 1 1 1 0 Leucine-zipper of ternary complex factor MIP1 Hanta_G1 PF01567.11 KLO13094.1 - 0.015 13.5 0.0 0.02 13.1 0.0 1.1 1 0 0 1 1 1 0 Hantavirus glycoprotein G1 MFS_1 PF07690.11 KLO13097.1 - 2.4e-28 98.8 14.4 2.4e-28 98.8 10.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily F-box-like PF12937.2 KLO13100.1 - 1.7e-08 34.0 0.0 4.1e-08 32.8 0.0 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KLO13100.1 - 0.014 15.0 0.3 0.041 13.5 0.0 2.0 2 0 0 2 2 2 0 F-box domain DUF3407 PF11887.3 KLO13100.1 - 0.019 14.2 0.0 0.027 13.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3407) Lzipper-MIP1 PF14389.1 KLO13100.1 - 0.056 13.5 0.5 0.089 12.9 0.3 1.3 1 0 0 1 1 1 0 Leucine-zipper of ternary complex factor MIP1 SKI PF01202.17 KLO13101.1 - 1.1e-12 48.0 0.0 1.7e-08 34.4 0.0 2.3 1 1 1 2 2 2 2 Shikimate kinase AAA_33 PF13671.1 KLO13101.1 - 6.1e-06 26.1 0.0 0.00012 22.0 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 KLO13101.1 - 2e-05 25.3 0.0 3.1e-05 24.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 KLO13101.1 - 4.6e-05 23.4 0.0 7.8e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain AAA_18 PF13238.1 KLO13101.1 - 8e-05 22.9 0.0 0.00051 20.3 0.0 2.3 1 1 0 1 1 1 1 AAA domain Cytidylate_kin2 PF13189.1 KLO13101.1 - 0.0012 18.8 0.0 0.0087 15.9 0.0 2.0 2 0 0 2 2 2 1 Cytidylate kinase-like family AAA PF00004.24 KLO13101.1 - 0.0077 16.4 0.0 0.017 15.3 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ABC_tran PF00005.22 KLO13101.1 - 0.023 15.0 0.4 0.051 13.8 0.1 1.9 2 1 0 2 2 2 0 ABC transporter AAA_22 PF13401.1 KLO13101.1 - 0.053 13.6 0.0 0.17 12.0 0.0 1.8 2 0 0 2 2 2 0 AAA domain NACHT PF05729.7 KLO13101.1 - 0.063 12.9 0.0 0.12 12.0 0.0 1.4 1 0 0 1 1 1 0 NACHT domain Zeta_toxin PF06414.7 KLO13101.1 - 0.065 12.3 0.0 0.11 11.6 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin APS_kinase PF01583.15 KLO13101.1 - 0.066 12.8 0.0 0.11 12.1 0.0 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase DUF258 PF03193.11 KLO13101.1 - 0.094 11.9 0.0 0.15 11.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 PduV-EutP PF10662.4 KLO13101.1 - 0.1 12.0 0.0 1.9 7.9 0.0 2.2 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Polysacc_deac_1 PF01522.16 KLO13105.1 - 5.8e-17 61.4 0.0 9.7e-17 60.7 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase DUF2194 PF09960.4 KLO13105.1 - 0.048 11.7 0.0 0.071 11.1 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2194) DUF2334 PF10096.4 KLO13105.1 - 0.078 12.3 0.0 0.17 11.2 0.0 1.6 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2334) 7TM_GPCR_Srh PF10318.4 KLO13106.1 - 0.003 16.4 4.7 0.003 16.4 3.3 2.2 2 0 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srh DUF2976 PF11190.3 KLO13106.1 - 0.013 15.0 1.4 0.04 13.4 1.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2976) p450 PF00067.17 KLO13107.1 - 2.5e-71 240.5 0.0 3.3e-71 240.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 AMP-binding PF00501.23 KLO13108.1 - 0.11 10.8 0.1 0.19 10.0 0.0 1.3 1 0 0 1 1 1 0 AMP-binding enzyme HOK_GEF PF01848.11 KLO13114.1 - 0.054 12.8 3.6 2.9 7.2 0.1 2.7 2 0 0 2 2 2 0 Hok/gef family ParG PF09274.5 KLO13115.1 - 0.034 14.0 0.0 0.078 12.9 0.0 1.5 1 0 0 1 1 1 0 ParG Flavi_NS1 PF00948.16 KLO13116.1 - 0.0089 14.4 0.0 0.014 13.7 0.0 1.2 1 0 0 1 1 1 1 Flavivirus non-structural Protein NS1 Tri3 PF07428.6 KLO13119.1 - 0.076 11.7 0.0 0.13 10.9 0.0 1.3 1 0 0 1 1 1 0 15-O-acetyltransferase Tri3 Tri3 PF07428.6 KLO13121.1 - 0.026 13.2 0.0 0.082 11.6 0.0 1.7 1 1 0 1 1 1 0 15-O-acetyltransferase Tri3 F-box-like PF12937.2 KLO13122.1 - 7.2e-09 35.2 0.0 5.6e-08 32.3 0.0 2.5 2 0 0 2 2 2 1 F-box-like F-box-like PF12937.2 KLO13123.1 - 1.1e-16 60.2 0.2 6.6e-08 32.1 0.0 3.2 2 0 0 2 2 2 2 F-box-like F-box PF00646.28 KLO13123.1 - 9.2e-06 25.1 0.3 0.13 11.9 0.2 2.9 2 0 0 2 2 2 2 F-box domain IncA PF04156.9 KLO13123.1 - 0.018 14.6 3.1 1.5 8.3 0.1 2.8 3 0 0 3 3 3 0 IncA protein Reo_sigmaC PF04582.7 KLO13123.1 - 0.035 13.2 4.2 1.1 8.3 0.3 3.0 3 0 0 3 3 3 0 Reovirus sigma C capsid protein Dickkopf_N PF04706.7 KLO13124.1 - 0.023 14.8 5.4 0.028 14.5 3.7 1.2 1 0 0 1 1 1 0 Dickkopf N-terminal cysteine-rich region Ferritin_2 PF13668.1 KLO13125.1 - 6.9e-41 139.4 0.0 1.1e-40 138.7 0.0 1.3 1 0 0 1 1 1 1 Ferritin-like domain Toxin_7 PF05980.7 KLO13126.1 - 0.087 12.8 3.9 0.17 11.9 2.7 1.5 1 0 0 1 1 1 0 Toxin 7 F-box-like PF12937.2 KLO13127.1 - 3.3e-08 33.1 0.2 7.1e-06 25.6 0.1 2.8 2 0 0 2 2 2 2 F-box-like F-box PF00646.28 KLO13127.1 - 0.011 15.3 0.6 0.31 10.7 0.1 2.7 2 0 0 2 2 2 0 F-box domain YwiC PF14256.1 KLO13129.1 - 8.8 6.4 15.5 8.6 6.4 4.6 2.7 2 1 0 2 2 2 0 YwiC-like protein Methyltransf_2 PF00891.13 KLO13130.1 - 2.8e-32 111.8 0.0 1.6e-31 109.3 0.0 1.9 1 1 0 1 1 1 1 O-methyltransferase Methyltransf_23 PF13489.1 KLO13130.1 - 7.8e-06 25.7 0.0 1.3e-05 24.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KLO13130.1 - 1.2e-05 25.8 0.0 4e-05 24.1 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 KLO13130.1 - 0.00056 20.3 0.0 0.00099 19.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KLO13130.1 - 0.0027 17.2 0.0 0.0054 16.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KLO13130.1 - 0.046 13.0 0.0 0.089 12.1 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_16 PF10294.4 KLO13130.1 - 0.052 12.9 0.0 0.15 11.5 0.0 1.7 2 0 0 2 2 2 0 Putative methyltransferase RPA_C PF08784.6 KLO13130.1 - 0.064 13.6 0.0 0.15 12.4 0.0 1.6 1 0 0 1 1 1 0 Replication protein A C terminal WT1 PF02165.10 KLO13130.1 - 0.081 12.0 0.0 0.12 11.4 0.0 1.2 1 0 0 1 1 1 0 Wilm's tumour protein Dimerisation PF08100.6 KLO13130.1 - 0.091 12.6 0.1 0.22 11.3 0.0 1.7 1 0 0 1 1 1 0 Dimerisation domain LCM PF04072.9 KLO13130.1 - 0.1 12.1 0.0 0.19 11.2 0.0 1.4 1 0 0 1 1 1 0 Leucine carboxyl methyltransferase DUF938 PF06080.7 KLO13130.1 - 0.17 11.4 0.0 0.4 10.1 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF938) p450 PF00067.17 KLO13132.1 - 1.2e-76 258.1 0.0 1.5e-76 257.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Strabismus PF06638.6 KLO13132.1 - 0.11 10.7 0.3 0.17 10.1 0.2 1.2 1 0 0 1 1 1 0 Strabismus protein UbiA PF01040.13 KLO13133.1 - 6.5e-25 87.8 23.3 8e-25 87.5 16.1 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family OSTbeta PF15048.1 KLO13134.1 - 0.61 10.1 1.9 1.6 8.8 0.1 2.3 2 0 0 2 2 2 0 Organic solute transporter subunit beta protein MFS_1 PF07690.11 KLO13139.1 - 2.7e-23 82.2 39.9 3.6e-23 81.8 22.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily OSTbeta PF15048.1 KLO13140.1 - 0.0077 16.2 0.4 1.2 9.1 0.0 2.3 2 0 0 2 2 2 2 Organic solute transporter subunit beta protein Acetyltransf_9 PF13527.1 KLO13142.1 - 0.0091 15.8 0.0 0.015 15.1 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain PAH PF02671.16 KLO13143.1 - 5.2e-19 67.5 0.7 1.2e-12 47.1 0.0 3.1 2 1 0 2 2 2 2 Paired amphipathic helix repeat Chlamy_scaf PF09675.5 KLO13143.1 - 0.12 12.3 2.4 4.7 7.2 0.1 2.9 2 1 1 3 3 3 0 Chlamydia-phage Chp2 scaffold (Chlamy_scaf) PAH PF02671.16 KLO13144.1 - 2.1e-23 81.6 1.2 2.5e-11 42.9 0.0 2.3 2 0 0 2 2 2 2 Paired amphipathic helix repeat Chlamy_scaf PF09675.5 KLO13144.1 - 0.011 15.7 0.1 1.9 8.5 0.0 2.3 2 0 0 2 2 2 0 Chlamydia-phage Chp2 scaffold (Chlamy_scaf) COX5A PF02284.11 KLO13144.1 - 0.051 13.5 0.0 0.53 10.2 0.0 2.2 2 0 0 2 2 2 0 Cytochrome c oxidase subunit Va PAH PF02671.16 KLO13146.1 - 6.8e-11 41.6 0.0 1.1e-10 40.9 0.0 1.3 1 0 0 1 1 1 1 Paired amphipathic helix repeat Toxin_37 PF11415.3 KLO13149.1 - 0.073 12.7 0.2 0.16 11.6 0.1 1.5 1 0 0 1 1 1 0 Antifungal peptide termicin F-box-like PF12937.2 KLO13151.1 - 3.4e-06 26.6 0.3 1.3e-05 24.7 0.2 2.1 1 0 0 1 1 1 1 F-box-like LRR_8 PF13855.1 KLO13151.1 - 0.011 15.4 4.0 11 5.8 0.5 4.3 3 1 1 4 4 4 0 Leucine rich repeat PAH PF02671.16 KLO13152.1 - 5.6e-07 29.0 0.0 9.5e-07 28.3 0.0 1.3 1 0 0 1 1 1 1 Paired amphipathic helix repeat zf-C3HC4_3 PF13920.1 KLO13153.1 - 0.67 9.6 7.5 1.3 8.7 5.2 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Zn_clus PF00172.13 KLO13153.1 - 0.72 9.8 10.7 1.7 8.6 7.4 1.7 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain XPG_I PF00867.13 KLO13155.1 - 6.8e-16 58.1 0.0 1.4e-15 57.0 0.0 1.6 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.12 KLO13155.1 - 0.00025 21.2 0.0 0.00046 20.3 0.0 1.4 1 0 0 1 1 1 1 XPG N-terminal domain Phage_int_SAM_4 PF13495.1 KLO13156.1 - 0.005 17.1 0.0 0.19 12.0 0.0 2.4 2 0 0 2 2 2 1 Phage integrase, N-terminal SAM-like domain Phage_integrase PF00589.17 KLO13156.1 - 0.064 12.9 0.0 0.92 9.1 0.0 2.6 2 1 0 2 2 2 0 Phage integrase family SIR2 PF02146.12 KLO13157.1 - 5.8e-26 91.2 0.0 8.1e-26 90.8 0.0 1.2 1 0 0 1 1 1 1 Sir2 family F-box-like PF12937.2 KLO13159.1 - 5.1e-07 29.3 1.3 1.2e-06 28.1 0.2 2.1 2 0 0 2 2 2 1 F-box-like Condensation PF00668.15 KLO13161.1 - 1.4e-06 27.3 0.0 6.3e-05 21.9 0.0 2.4 2 1 0 2 2 2 2 Condensation domain Transferase PF02458.10 KLO13161.1 - 4.9e-05 21.9 0.0 0.00013 20.5 0.0 1.6 2 0 0 2 2 2 1 Transferase family F-box-like PF12937.2 KLO13162.1 - 0.00022 20.8 0.2 0.00064 19.3 0.1 1.8 1 0 0 1 1 1 1 F-box-like LRR_8 PF13855.1 KLO13162.1 - 0.2 11.4 2.9 0.87 9.3 0.9 2.5 2 0 0 2 2 2 0 Leucine rich repeat F-box-like PF12937.2 KLO13163.1 - 7.4e-07 28.8 0.4 7.4e-07 28.8 0.3 2.5 3 0 0 3 3 3 1 F-box-like F-box PF00646.28 KLO13163.1 - 4.5 7.0 6.9 18 5.1 2.4 3.4 2 1 0 2 2 2 0 F-box domain F-box-like PF12937.2 KLO13165.1 - 9.5e-05 22.0 0.5 0.00087 18.9 0.1 2.7 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 KLO13165.1 - 0.022 14.3 2.5 11 5.7 0.1 3.8 3 0 0 3 3 3 0 F-box domain LRR_8 PF13855.1 KLO13165.1 - 0.11 12.3 0.9 5.2 6.8 0.0 3.9 4 1 0 4 4 4 0 Leucine rich repeat Transferase PF02458.10 KLO13166.1 - 9.5e-06 24.3 0.0 0.00044 18.8 0.0 2.0 2 0 0 2 2 2 2 Transferase family Condensation PF00668.15 KLO13166.1 - 0.00037 19.4 0.0 0.0023 16.8 0.0 2.1 1 1 0 1 1 1 1 Condensation domain F-box-like PF12937.2 KLO13167.1 - 4.4e-05 23.1 0.1 0.00012 21.7 0.1 1.8 1 0 0 1 1 1 1 F-box-like F-box-like PF12937.2 KLO13168.1 - 7.5e-05 22.3 0.9 0.00027 20.6 0.6 2.1 1 0 0 1 1 1 1 F-box-like DSPc PF00782.15 KLO13169.1 - 1e-26 93.0 0.0 1.2e-26 92.8 0.0 1.0 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 KLO13169.1 - 0.00011 21.6 0.0 0.00012 21.4 0.0 1.1 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTS_IIB PF02302.12 KLO13169.1 - 0.12 12.9 0.0 0.3 11.5 0.0 1.7 2 0 0 2 2 2 0 PTS system, Lactose/Cellobiose specific IIB subunit DSPc PF00782.15 KLO13174.1 - 5.6e-29 100.3 0.0 7.4e-29 100.0 0.0 1.1 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 KLO13174.1 - 5.8e-05 22.5 0.0 6.9e-05 22.3 0.0 1.1 1 0 0 1 1 1 1 Protein-tyrosine phosphatase CDKN3 PF05706.7 KLO13174.1 - 0.089 12.2 0.1 0.13 11.6 0.0 1.3 1 0 0 1 1 1 0 Cyclin-dependent kinase inhibitor 3 (CDKN3) MTP18 PF10558.4 KLO13174.1 - 0.15 11.9 0.4 2.4 8.0 0.1 2.0 1 1 1 2 2 2 0 Mitochondrial 18 KDa protein (MTP18) DSPc PF00782.15 KLO13176.1 - 2.4e-30 104.8 0.0 3e-30 104.5 0.0 1.0 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 KLO13176.1 - 2e-05 24.0 0.0 2.3e-05 23.8 0.0 1.1 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.1 KLO13176.1 - 0.064 13.3 0.0 0.11 12.5 0.0 1.3 1 0 0 1 1 1 0 Inositol hexakisphosphate F-box-like PF12937.2 KLO13177.1 - 0.0019 17.8 0.0 0.0059 16.3 0.0 2.0 1 0 0 1 1 1 1 F-box-like LRR_8 PF13855.1 KLO13177.1 - 0.0062 16.2 4.5 0.87 9.3 0.0 4.8 5 1 0 5 5 5 1 Leucine rich repeat DUF2132 PF09905.4 KLO13177.1 - 0.08 12.9 0.0 0.29 11.1 0.0 2.0 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2132) LRR_4 PF12799.2 KLO13177.1 - 0.11 12.1 7.4 3.5 7.3 0.0 4.5 4 1 1 5 5 5 0 Leucine Rich repeats (2 copies) Zn_clus PF00172.13 KLO13178.1 - 2.1e-18 65.9 25.3 3.9e-09 36.2 6.3 2.3 2 0 0 2 2 2 2 Fungal Zn(2)-Cys(6) binuclear cluster domain Septin PF00735.13 KLO13178.1 - 2.1e-10 40.1 0.0 1.4e-07 30.8 0.0 4.1 5 0 0 5 5 5 1 Septin Nucleo_P87 PF07267.6 KLO13178.1 - 2.8 6.5 3.3 3.4 6.2 0.4 2.1 2 0 0 2 2 2 0 Nucleopolyhedrovirus capsid protein P87 V_ATPase_I PF01496.14 KLO13183.1 - 0.011 13.6 3.1 0.014 13.2 2.1 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Tom22 PF04281.8 KLO13184.1 - 0.13 11.7 0.3 0.19 11.2 0.2 1.3 1 0 0 1 1 1 0 Mitochondrial import receptor subunit Tom22 Methyltransf_2 PF00891.13 KLO13187.1 - 4.3e-28 98.1 0.0 1.2e-27 96.6 0.0 1.7 1 1 0 1 1 1 1 O-methyltransferase Dimerisation PF08100.6 KLO13187.1 - 0.0029 17.3 0.0 0.014 15.2 0.0 2.2 2 0 0 2 2 2 1 Dimerisation domain Methyltransf_18 PF12847.2 KLO13187.1 - 0.027 15.0 0.0 0.055 14.0 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain RrnaAD PF00398.15 KLO13187.1 - 0.035 13.1 0.0 0.062 12.3 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase MTS PF05175.9 KLO13187.1 - 0.046 13.1 0.0 0.093 12.1 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_31 PF13847.1 KLO13187.1 - 0.14 11.7 0.0 0.26 10.8 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_2 PF00891.13 KLO13188.1 - 1.8e-28 99.3 0.0 4.9e-28 97.9 0.0 1.6 1 1 0 1 1 1 1 O-methyltransferase Dimerisation PF08100.6 KLO13188.1 - 0.0035 17.1 0.0 0.012 15.3 0.0 2.0 2 0 0 2 2 2 1 Dimerisation domain RrnaAD PF00398.15 KLO13188.1 - 0.0043 16.1 0.0 0.0074 15.3 0.0 1.3 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase MTS PF05175.9 KLO13188.1 - 0.059 12.7 0.0 0.11 11.8 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_23 PF13489.1 KLO13188.1 - 0.063 12.9 0.0 0.12 12.0 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_18 PF12847.2 KLO13188.1 - 0.066 13.8 0.0 0.16 12.5 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain UbiA PF01040.13 KLO13193.1 - 4.3e-13 49.0 20.0 5.6e-13 48.7 13.9 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family UbiA PF01040.13 KLO13194.1 - 2.8e-05 23.4 10.5 3.7e-05 23.0 7.3 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family p450 PF00067.17 KLO13195.1 - 4.5e-65 219.9 0.0 5.2e-65 219.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF3083 PF11281.3 KLO13195.1 - 0.041 13.0 0.0 0.061 12.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3083) SARS_3b PF12383.3 KLO13197.1 - 0.0093 15.9 5.5 0.026 14.4 1.2 2.3 2 0 0 2 2 2 2 Severe acute respiratory syndrome coronavirus 3b protein p450 PF00067.17 KLO13198.1 - 3e-70 237.0 0.0 3.4e-70 236.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Methyltransf_2 PF00891.13 KLO13199.1 - 1e-24 87.0 0.0 2.9e-24 85.6 0.0 1.7 1 1 0 1 1 1 1 O-methyltransferase Methyltransf_18 PF12847.2 KLO13199.1 - 0.0021 18.6 0.0 0.0056 17.2 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Rrf2 PF02082.15 KLO13199.1 - 0.025 14.7 0.0 0.43 10.7 0.0 2.3 2 0 0 2 2 2 0 Transcriptional regulator Dimerisation PF08100.6 KLO13199.1 - 0.048 13.4 0.0 0.13 12.1 0.0 1.8 1 0 0 1 1 1 0 Dimerisation domain RPA_C PF08784.6 KLO13199.1 - 0.085 13.2 0.0 0.18 12.2 0.0 1.4 1 0 0 1 1 1 0 Replication protein A C terminal MarR_2 PF12802.2 KLO13199.1 - 0.098 12.3 0.0 0.55 9.9 0.0 2.1 2 0 0 2 2 2 0 MarR family HTH_IclR PF09339.5 KLO13199.1 - 0.11 12.1 0.0 0.49 10.0 0.0 2.2 1 0 0 1 1 1 0 IclR helix-turn-helix domain Methyltransf_2 PF00891.13 KLO13200.1 - 3.2e-30 105.0 0.0 7.2e-30 103.9 0.0 1.5 1 1 0 1 1 1 1 O-methyltransferase Methyltransf_18 PF12847.2 KLO13200.1 - 3.2e-05 24.4 0.0 0.00011 22.7 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 KLO13200.1 - 0.0004 20.8 0.0 0.0012 19.2 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KLO13200.1 - 0.00055 19.3 0.3 0.0045 16.3 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_23 PF13489.1 KLO13200.1 - 0.0012 18.5 0.0 0.0023 17.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Dimerisation PF08100.6 KLO13200.1 - 0.012 15.4 0.0 0.032 14.0 0.0 1.8 1 0 0 1 1 1 0 Dimerisation domain Methyltransf_4 PF02390.12 KLO13200.1 - 0.019 14.0 0.0 0.037 13.0 0.0 1.4 1 0 0 1 1 1 0 Putative methyltransferase Methyltransf_31 PF13847.1 KLO13200.1 - 0.02 14.4 0.0 0.079 12.5 0.0 2.0 2 1 0 2 2 2 0 Methyltransferase domain YqbF PF14553.1 KLO13200.1 - 0.1 12.2 0.0 0.21 11.3 0.0 1.5 1 0 0 1 1 1 0 YqbF, hypothetical protein domain p450 PF00067.17 KLO13201.1 - 1.2e-65 221.8 0.0 1.5e-65 221.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Methyltransf_2 PF00891.13 KLO13203.1 - 5.6e-29 101.0 0.0 1.6e-28 99.5 0.0 1.6 1 1 0 1 1 1 1 O-methyltransferase Methyltransf_18 PF12847.2 KLO13203.1 - 0.00012 22.5 0.0 0.00026 21.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KLO13203.1 - 0.00039 20.8 0.0 0.00079 19.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KLO13203.1 - 0.0023 17.6 0.0 0.0051 16.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KLO13203.1 - 0.0025 17.3 0.0 0.0055 16.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KLO13203.1 - 0.0026 17.1 0.0 0.0048 16.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Dimerisation PF08100.6 KLO13203.1 - 0.045 13.5 0.0 0.12 12.1 0.0 1.7 1 0 0 1 1 1 0 Dimerisation domain Methyltransf_4 PF02390.12 KLO13203.1 - 0.058 12.4 0.0 0.096 11.7 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase RPA_C PF08784.6 KLO13203.1 - 0.092 13.1 0.0 0.24 11.8 0.0 1.7 1 0 0 1 1 1 0 Replication protein A C terminal adh_short PF00106.20 KLO13204.1 - 2.4e-24 86.1 3.3 3.8e-24 85.4 2.3 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KLO13204.1 - 4.1e-13 49.3 0.5 6e-13 48.8 0.4 1.3 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 KLO13204.1 - 2.4e-11 43.8 1.6 2.6e-10 40.5 1.1 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 KLO13204.1 - 0.017 14.5 0.5 0.034 13.5 0.1 1.8 2 1 1 3 3 3 0 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 KLO13204.1 - 0.051 13.5 2.1 0.24 11.3 1.1 2.0 1 1 1 2 2 2 0 NADH(P)-binding Ldh_1_N PF00056.18 KLO13204.1 - 0.054 13.3 0.8 0.11 12.2 0.5 1.6 1 1 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain Trp_halogenase PF04820.9 KLO13206.1 - 2e-34 119.0 0.7 4.3e-19 68.4 0.3 2.6 1 1 1 2 2 2 2 Tryptophan halogenase FAD_binding_3 PF01494.14 KLO13206.1 - 1.3e-15 57.3 0.0 3e-15 56.1 0.0 1.6 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 KLO13206.1 - 4.5e-09 35.6 0.3 0.00085 18.3 0.1 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 KLO13206.1 - 1.6e-07 31.4 0.1 6.5e-07 29.4 0.0 2.0 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 KLO13206.1 - 7.5e-07 28.5 0.0 1.3e-06 27.7 0.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.9 KLO13206.1 - 0.00018 20.0 0.1 0.002 16.6 0.0 2.0 2 0 0 2 2 2 1 HI0933-like protein GIDA PF01134.17 KLO13206.1 - 0.00044 19.2 0.0 0.00074 18.4 0.0 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A FAD_binding_2 PF00890.19 KLO13206.1 - 0.00052 18.9 0.2 0.0025 16.7 0.0 2.0 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_3 PF13738.1 KLO13206.1 - 0.0026 17.8 0.0 0.0048 16.9 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 KLO13206.1 - 0.0027 18.0 0.1 1.5 9.2 0.0 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KLO13206.1 - 0.007 16.3 0.0 0.007 16.3 0.0 2.1 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 KLO13206.1 - 0.013 14.6 0.0 0.068 12.2 0.0 2.0 2 0 0 2 2 2 0 Thi4 family ThiF PF00899.16 KLO13206.1 - 0.069 12.9 0.2 0.3 10.8 0.2 2.0 2 0 0 2 2 2 0 ThiF family p450 PF00067.17 KLO13207.1 - 8.4e-68 228.9 0.0 1e-67 228.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF3083 PF11281.3 KLO13207.1 - 0.0085 15.2 0.0 0.013 14.6 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3083) Pyr_redox_3 PF13738.1 KLO13208.1 - 5.3e-23 82.1 0.1 3.5e-22 79.4 0.1 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 KLO13208.1 - 4e-21 74.8 0.0 2.3e-20 72.2 0.0 2.1 1 1 1 2 2 2 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.1 KLO13208.1 - 1.5e-15 56.9 0.1 3.1e-12 46.0 0.0 3.0 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 KLO13208.1 - 6.1e-10 39.3 0.0 2.7e-07 30.6 0.0 2.2 1 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase 2-Hacid_dh_C PF02826.14 KLO13208.1 - 2.3e-06 26.8 0.7 0.0054 15.8 0.0 3.0 3 0 0 3 3 3 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Shikimate_DH PF01488.15 KLO13208.1 - 8e-06 26.0 0.1 0.0017 18.4 0.0 2.4 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase Pyr_redox PF00070.22 KLO13208.1 - 8.5e-06 26.0 0.2 0.055 13.8 0.1 3.0 3 0 0 3 3 2 2 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.13 KLO13208.1 - 2.1e-05 24.5 0.1 0.021 14.7 0.0 2.5 2 0 0 2 2 2 2 TrkA-N domain DAO PF01266.19 KLO13208.1 - 5.2e-05 22.3 1.1 0.17 10.7 0.0 3.2 2 1 0 3 3 3 1 FAD dependent oxidoreductase Thi4 PF01946.12 KLO13208.1 - 6.5e-05 22.1 0.1 0.025 13.6 0.0 2.4 2 0 0 2 2 2 1 Thi4 family HI0933_like PF03486.9 KLO13208.1 - 0.00019 20.0 0.9 0.0055 15.2 0.0 2.9 3 0 0 3 3 3 1 HI0933-like protein NAD_binding_8 PF13450.1 KLO13208.1 - 0.00031 20.7 0.1 0.002 18.1 0.0 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 KLO13208.1 - 0.00049 19.8 2.5 0.22 11.2 0.0 3.1 4 0 0 4 4 3 2 FAD-NAD(P)-binding Lycopene_cycl PF05834.7 KLO13208.1 - 0.00092 18.2 0.1 0.14 11.0 0.0 2.6 3 0 0 3 3 3 1 Lycopene cyclase protein F420_oxidored PF03807.12 KLO13208.1 - 0.0014 19.0 0.1 0.16 12.4 0.0 3.0 3 0 0 3 3 3 1 NADP oxidoreductase coenzyme F420-dependent SnoaL_2 PF12680.2 KLO13208.1 - 0.0037 17.6 0.6 0.21 12.0 0.0 2.8 2 0 0 2 2 2 1 SnoaL-like domain 3HCDH_N PF02737.13 KLO13208.1 - 0.0059 16.2 0.4 0.65 9.6 0.0 2.3 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain GDI PF00996.13 KLO13208.1 - 0.0076 14.6 0.0 0.012 13.9 0.0 1.2 1 0 0 1 1 1 1 GDP dissociation inhibitor FAD_binding_3 PF01494.14 KLO13208.1 - 0.0094 15.0 0.1 0.43 9.5 0.0 2.2 2 0 0 2 2 2 1 FAD binding domain ApbA PF02558.11 KLO13208.1 - 0.0096 15.3 0.0 1.5 8.2 0.0 2.5 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA FAD_binding_2 PF00890.19 KLO13208.1 - 0.0099 14.7 0.0 0.64 8.7 0.0 2.7 3 0 0 3 3 3 1 FAD binding domain GIDA PF01134.17 KLO13208.1 - 0.013 14.4 1.3 1.4 7.6 0.0 3.0 3 0 0 3 3 3 0 Glucose inhibited division protein A ELFV_dehydrog PF00208.16 KLO13208.1 - 0.021 14.3 0.0 0.15 11.6 0.0 1.9 2 0 0 2 2 2 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase AlaDh_PNT_C PF01262.16 KLO13208.1 - 0.027 14.0 0.1 0.69 9.4 0.0 2.6 3 0 0 3 3 3 0 Alanine dehydrogenase/PNT, C-terminal domain CoA_binding PF02629.14 KLO13208.1 - 0.035 14.5 0.1 10 6.6 0.0 2.5 2 0 0 2 2 2 0 CoA binding domain ThiF PF00899.16 KLO13208.1 - 0.044 13.6 1.5 1.8 8.4 0.6 2.3 2 0 0 2 2 2 0 ThiF family UbiA PF01040.13 KLO13209.1 - 3.4e-25 88.7 20.4 4.2e-25 88.4 14.1 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family DUF3817 PF12823.2 KLO13211.1 - 0.021 15.2 1.5 0.073 13.5 1.1 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF3817) Methyltransf_2 PF00891.13 KLO13212.1 - 1.5e-26 93.1 0.0 3e-26 92.1 0.0 1.5 1 1 0 1 1 1 1 O-methyltransferase Methyltransf_18 PF12847.2 KLO13212.1 - 0.011 16.3 0.0 0.027 15.0 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_23 PF13489.1 KLO13212.1 - 0.017 14.8 0.0 0.041 13.6 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Dimerisation PF08100.6 KLO13212.1 - 0.07 12.9 0.0 0.21 11.4 0.0 1.9 1 0 0 1 1 1 0 Dimerisation domain MTS PF05175.9 KLO13212.1 - 0.12 11.7 0.0 0.22 10.8 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_12 PF08242.7 KLO13212.1 - 0.12 12.8 0.0 0.28 11.6 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain DUF4177 PF13783.1 KLO13212.1 - 0.14 11.7 0.0 0.6 9.7 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4177) DUF4620 PF15399.1 KLO13213.1 - 0.14 12.2 0.4 0.28 11.3 0.1 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4620) adh_short_C2 PF13561.1 KLO13216.1 - 2.2e-23 83.3 0.4 2.7e-23 82.9 0.3 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 KLO13216.1 - 9e-07 28.9 5.1 1.3e-06 28.4 3.4 1.4 1 1 0 1 1 1 1 short chain dehydrogenase THF_DHG_CYH_C PF02882.14 KLO13216.1 - 0.0014 17.7 0.8 0.0024 16.9 0.5 1.4 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain KR PF08659.5 KLO13216.1 - 0.0032 17.1 2.4 0.0076 15.9 1.7 1.8 1 1 0 1 1 1 1 KR domain Eno-Rase_NADH_b PF12242.3 KLO13216.1 - 0.015 15.0 1.9 0.041 13.6 1.3 1.7 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase NAD_binding_7 PF13241.1 KLO13216.1 - 0.024 14.9 0.7 0.041 14.1 0.2 1.7 2 0 0 2 2 2 0 Putative NAD(P)-binding GRDA PF04723.9 KLO13216.1 - 0.12 12.0 1.7 0.77 9.4 0.5 2.5 2 1 1 3 3 3 0 Glycine reductase complex selenoprotein A ADH_zinc_N PF00107.21 KLO13216.1 - 0.16 11.5 4.0 0.35 10.4 0.9 2.4 2 0 0 2 2 2 0 Zinc-binding dehydrogenase NAD_binding_10 PF13460.1 KLO13216.1 - 0.36 10.8 6.2 0.23 11.4 2.6 2.0 2 1 0 2 2 2 0 NADH(P)-binding Abhydrolase_5 PF12695.2 KLO13216.1 - 2.3 7.9 4.4 0.39 10.4 0.3 1.7 2 1 0 2 2 2 0 Alpha/beta hydrolase family Methyltransf_2 PF00891.13 KLO13218.1 - 1.1e-26 93.5 0.0 3.3e-26 91.9 0.0 1.7 1 1 0 1 1 1 1 O-methyltransferase Dimerisation PF08100.6 KLO13218.1 - 0.02 14.6 0.0 0.057 13.2 0.0 1.8 1 0 0 1 1 1 0 Dimerisation domain MTS PF05175.9 KLO13218.1 - 0.024 14.0 0.0 0.047 13.0 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_18 PF12847.2 KLO13218.1 - 0.032 14.8 0.0 0.091 13.3 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_4 PF02390.12 KLO13218.1 - 0.054 12.5 0.0 0.098 11.6 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase DUF938 PF06080.7 KLO13218.1 - 0.068 12.7 0.0 1.9 7.9 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF938) Methyltransf_12 PF08242.7 KLO13218.1 - 0.088 13.2 0.0 0.47 10.9 0.0 2.2 2 0 0 2 2 2 0 Methyltransferase domain Acetyltransf_3 PF13302.1 KLO13219.1 - 4.9e-07 30.0 0.0 6.2e-07 29.6 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain CENP-B_dimeris PF09026.5 KLO13220.1 - 0.0065 16.6 8.5 0.8 9.9 1.6 2.5 2 0 0 2 2 2 2 Centromere protein B dimerisation domain IncA PF04156.9 KLO13220.1 - 0.3 10.6 8.1 1.3 8.5 5.5 1.9 1 1 0 1 1 1 0 IncA protein TMF_TATA_bd PF12325.3 KLO13220.1 - 4 7.1 8.8 2.7 7.7 0.8 3.0 2 1 1 3 3 3 0 TATA element modulatory factor 1 TATA binding TPR_MLP1_2 PF07926.7 KLO13220.1 - 4.1 7.1 9.3 32 4.2 0.0 2.7 2 1 1 3 3 3 0 TPR/MLP1/MLP2-like protein Glyco_hydro_63 PF03200.11 KLO13223.1 - 1.1e-236 787.5 0.0 9e-236 784.5 0.0 1.9 1 1 0 1 1 1 1 Mannosyl oligosaccharide glucosidase Trehalase PF01204.13 KLO13223.1 - 0.00037 19.2 0.0 0.00057 18.6 0.0 1.3 1 0 0 1 1 1 1 Trehalase GDE_C PF06202.9 KLO13223.1 - 0.0019 16.9 0.0 0.0034 16.1 0.0 1.4 1 0 0 1 1 1 1 Amylo-alpha-1,6-glucosidase dsrm PF00035.20 KLO13227.1 - 3.1e-12 46.8 0.0 3.4e-12 46.7 0.0 1.0 1 0 0 1 1 1 1 Double-stranded RNA binding motif DND1_DSRM PF14709.1 KLO13227.1 - 3.8e-05 23.8 0.0 4.7e-05 23.5 0.0 1.1 1 0 0 1 1 1 1 double strand RNA binding domain from DEAD END PROTEIN 1 DUF4260 PF14079.1 KLO13227.1 - 0.049 13.4 0.0 0.049 13.4 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4260) dsrm PF00035.20 KLO13228.1 - 1.7e-11 44.5 0.0 1.8e-11 44.4 0.0 1.0 1 0 0 1 1 1 1 Double-stranded RNA binding motif DND1_DSRM PF14709.1 KLO13228.1 - 1.2e-06 28.6 0.0 1.7e-06 28.2 0.0 1.2 1 0 0 1 1 1 1 double strand RNA binding domain from DEAD END PROTEIN 1 dsrm PF00035.20 KLO13229.1 - 1e-10 42.0 0.0 1.4e-10 41.6 0.0 1.2 1 0 0 1 1 1 1 Double-stranded RNA binding motif DND1_DSRM PF14709.1 KLO13229.1 - 0.0011 19.2 0.0 0.0015 18.7 0.0 1.3 1 0 0 1 1 1 1 double strand RNA binding domain from DEAD END PROTEIN 1 ADIP PF11559.3 KLO13230.1 - 7.7e-19 68.0 10.3 7.7e-19 68.0 7.2 2.8 3 0 0 3 3 3 1 Afadin- and alpha -actinin-Binding AIP3 PF03915.8 KLO13230.1 - 0.0026 16.7 5.6 0.0056 15.6 3.9 1.5 1 0 0 1 1 1 1 Actin interacting protein 3 DUF720 PF05302.6 KLO13230.1 - 0.06 13.1 4.9 0.13 12.0 3.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF720) Lectin_N PF03954.9 KLO13230.1 - 1.8 7.9 8.2 1.4 8.3 3.5 2.2 2 0 0 2 2 2 0 Hepatic lectin, N-terminal domain APG6 PF04111.7 KLO13230.1 - 4.2 6.3 11.5 9.4 5.1 8.0 1.5 1 0 0 1 1 1 0 Autophagy protein Apg6 V_ATPase_I PF01496.14 KLO13230.1 - 7.3 4.3 5.0 12 3.6 2.3 1.9 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family FUSC PF04632.7 KLO13230.1 - 9.7 4.4 9.4 3.2 6.0 4.5 1.5 2 0 0 2 2 2 0 Fusaric acid resistance protein family dsrm PF00035.20 KLO13231.1 - 4.5e-11 43.1 0.0 5.1e-11 42.9 0.0 1.0 1 0 0 1 1 1 1 Double-stranded RNA binding motif DND1_DSRM PF14709.1 KLO13231.1 - 0.0034 17.6 0.3 0.01 16.0 0.2 1.7 1 1 0 1 1 1 1 double strand RNA binding domain from DEAD END PROTEIN 1 dsrm PF00035.20 KLO13233.1 - 6e-12 45.9 0.5 6.9e-12 45.7 0.3 1.1 1 0 0 1 1 1 1 Double-stranded RNA binding motif DUF2188 PF09954.4 KLO13233.1 - 0.021 14.7 1.2 0.031 14.1 0.8 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2188) Peptidase_C97 PF05903.9 KLO13233.1 - 0.045 13.5 0.0 0.047 13.4 0.0 1.2 1 0 0 1 1 1 0 PPPDE putative peptidase domain DND1_DSRM PF14709.1 KLO13233.1 - 0.059 13.6 0.7 0.13 12.5 0.5 1.6 1 1 0 1 1 1 0 double strand RNA binding domain from DEAD END PROTEIN 1 PAP2 PF01569.16 KLO13235.1 - 2.2e-14 53.2 7.1 2.9e-14 52.8 4.6 1.4 1 1 0 1 1 1 1 PAP2 superfamily DUF4451 PF14616.1 KLO13236.1 - 2.6e-07 30.4 4.5 0.0079 15.9 0.3 3.2 2 1 1 3 3 3 3 Domain of unknown function (DUF4451) DiS_P_DiS PF06750.8 KLO13236.1 - 0.0079 15.9 0.0 0.021 14.5 0.0 1.7 1 0 0 1 1 1 1 Bacterial Peptidase A24 N-terminal domain HypA PF01155.14 KLO13236.1 - 0.31 10.7 1.5 3.7 7.2 0.4 2.6 2 1 0 2 2 2 0 Hydrogenase expression/synthesis hypA family Glyco_hyd_65N_2 PF14498.1 KLO13238.1 - 6.9e-40 137.1 0.1 1.1e-39 136.5 0.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 65, N-terminal domain PGM_PMM_I PF02878.11 KLO13239.1 - 6.6e-37 126.0 0.1 1e-36 125.4 0.1 1.3 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_III PF02880.11 KLO13239.1 - 1.5e-25 89.4 0.0 6.9e-25 87.2 0.0 2.1 3 0 0 3 3 3 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_II PF02879.11 KLO13239.1 - 1.9e-13 50.6 0.0 5.4e-13 49.1 0.0 1.8 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.15 KLO13239.1 - 1.3e-07 31.4 0.0 3.5e-07 30.1 0.0 1.7 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain Acetyltransf_3 PF13302.1 KLO13240.1 - 0.00058 20.0 0.0 0.001 19.2 0.0 1.4 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 KLO13241.1 - 3.4e-07 30.5 0.0 4.8e-07 30.0 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 KLO13241.1 - 0.035 14.1 0.0 0.074 13.0 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family Acetyltransf_3 PF13302.1 KLO13242.1 - 1.3e-07 31.8 0.0 1.9e-07 31.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 KLO13242.1 - 0.054 13.5 0.0 0.16 12.0 0.0 1.9 1 1 0 1 1 1 0 Acetyltransferase (GNAT) family Acetyltransf_3 PF13302.1 KLO13243.1 - 5.8e-08 33.0 0.0 7.7e-08 32.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Carb_kinase PF01256.12 KLO13244.1 - 9.6e-49 165.8 0.0 1.2e-48 165.5 0.0 1.1 1 0 0 1 1 1 1 Carbohydrate kinase Phos_pyr_kin PF08543.7 KLO13244.1 - 0.0014 17.8 0.0 0.0027 16.9 0.0 1.6 1 1 1 2 2 2 1 Phosphomethylpyrimidine kinase DOPA_dioxygen PF08883.6 KLO13245.1 - 1.8e-25 89.0 0.0 2.6e-25 88.5 0.0 1.3 1 0 0 1 1 1 1 Dopa 4,5-dioxygenase family DUF383 PF04063.9 KLO13247.1 - 1.1e-51 175.0 0.0 5.2e-51 172.9 0.0 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF383) DUF384 PF04064.8 KLO13247.1 - 2.1e-18 65.6 0.1 4.3e-18 64.6 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF384) HEAT PF02985.17 KLO13247.1 - 0.017 15.1 0.0 0.099 12.7 0.0 2.5 1 0 0 1 1 1 0 HEAT repeat HEAT_2 PF13646.1 KLO13247.1 - 0.09 13.0 0.2 2.4 8.4 0.0 3.0 3 0 0 3 3 3 0 HEAT repeats Spt20 PF12090.3 KLO13248.1 - 8.1e-31 106.7 0.0 1.6e-30 105.8 0.0 1.5 1 1 0 1 1 1 1 Spt20 family GATA PF00320.22 KLO13249.1 - 9.3e-15 53.6 1.8 1.7e-14 52.8 1.3 1.5 1 0 0 1 1 1 1 GATA zinc finger DEAD PF00270.24 KLO13252.1 - 3.2e-44 150.4 0.0 3.1e-43 147.1 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KLO13252.1 - 4.8e-28 96.8 0.0 1.1e-27 95.6 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 KLO13252.1 - 0.00025 20.9 0.0 0.00053 19.8 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Ribosomal_S28e PF01200.13 KLO13252.1 - 0.041 13.6 0.2 0.75 9.5 0.0 2.4 2 0 0 2 2 2 0 Ribosomal protein S28e CMS1 PF14617.1 KLO13252.1 - 0.065 12.2 0.0 0.11 11.5 0.0 1.3 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit Helicase_C_2 PF13307.1 KLO13252.1 - 0.11 12.5 0.0 0.2 11.5 0.0 1.4 1 0 0 1 1 1 0 Helicase C-terminal domain DUF1253 PF06862.7 KLO13252.1 - 0.2 10.0 0.0 0.4 9.0 0.0 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1253) Cofilin_ADF PF00241.15 KLO13253.1 - 0.0001 22.1 0.0 0.00018 21.4 0.0 1.4 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein PH PF00169.24 KLO13253.1 - 0.069 13.3 0.0 0.27 11.4 0.0 2.0 1 0 0 1 1 1 0 PH domain DUF1295 PF06966.7 KLO13254.1 - 8.2e-48 162.7 1.7 1.3e-47 162.1 1.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) PEMT PF04191.8 KLO13254.1 - 4.4e-06 26.7 1.4 1.2e-05 25.3 0.0 2.3 2 0 0 2 2 2 1 Phospholipid methyltransferase Steroid_dh PF02544.11 KLO13254.1 - 0.036 13.8 0.0 0.036 13.8 0.0 2.9 3 1 1 4 4 4 0 3-oxo-5-alpha-steroid 4-dehydrogenase Mus7 PF09462.5 KLO13255.1 - 1.1e-81 275.5 0.0 1.5e-81 275.1 0.0 1.2 1 0 0 1 1 1 1 Mus7/MMS22 family Acetyltransf_7 PF13508.1 KLO13256.1 - 0.0052 16.9 0.0 0.014 15.5 0.0 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 KLO13256.1 - 0.007 16.2 0.0 0.018 14.8 0.0 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain LRR_4 PF12799.2 KLO13257.1 - 1.2e-09 37.5 5.5 7.4e-08 31.8 0.8 3.1 1 1 2 3 3 3 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KLO13257.1 - 4.8e-07 29.4 2.9 4.8e-07 29.4 2.0 2.0 2 0 0 2 2 2 1 Leucine rich repeat LRR_1 PF00560.28 KLO13257.1 - 0.0013 18.4 5.8 3 8.2 0.1 4.7 5 0 0 5 5 5 2 Leucine Rich Repeat LRR_7 PF13504.1 KLO13257.1 - 0.2 11.9 1.6 11 6.7 0.0 3.6 4 0 0 4 4 4 0 Leucine rich repeat Slp PF03843.8 KLO13259.1 - 0.13 11.1 0.0 0.23 10.4 0.0 1.3 1 0 0 1 1 1 0 Outer membrane lipoprotein Slp family DLH PF01738.13 KLO13262.1 - 1.3e-19 70.4 0.0 1.6e-19 70.0 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 KLO13262.1 - 2e-07 30.8 0.0 3.9e-07 29.9 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family adh_short PF00106.20 KLO13263.1 - 1.7e-22 80.1 0.6 2.4e-22 79.6 0.4 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KLO13263.1 - 1.3e-11 44.5 0.8 2.6e-11 43.4 0.6 1.5 1 1 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 KLO13263.1 - 3.5e-09 36.8 0.0 4.4e-09 36.4 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase 3Beta_HSD PF01073.14 KLO13263.1 - 0.049 12.3 0.2 0.07 11.8 0.1 1.3 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family AraC_binding_2 PF14525.1 KLO13263.1 - 0.052 13.1 0.0 0.087 12.3 0.0 1.3 1 0 0 1 1 1 0 AraC-binding-like domain Glutaredoxin PF00462.19 KLO13264.1 - 8.9e-17 60.8 0.0 1.3e-16 60.2 0.0 1.3 1 0 0 1 1 1 1 Glutaredoxin Med26 PF08711.6 KLO13265.1 - 6.6e-05 22.3 0.0 0.00012 21.4 0.0 1.5 1 0 0 1 1 1 1 TFIIS helical bundle-like domain LEDGF PF11467.3 KLO13265.1 - 0.0026 17.4 0.2 0.006 16.2 0.1 1.7 1 1 1 2 2 2 1 Lens epithelium-derived growth factor (LEDGF) MFS_1 PF07690.11 KLO13266.1 - 2.4e-31 108.7 41.2 2.1e-30 105.6 20.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Abhydrolase_6 PF12697.2 KLO13267.1 - 9e-12 45.3 0.0 1.4e-11 44.7 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KLO13267.1 - 0.0036 17.0 0.0 0.0048 16.6 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KLO13268.1 - 4.1e-12 46.4 0.1 5.4e-12 46.0 0.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KLO13268.1 - 0.0009 19.0 0.0 0.0023 17.6 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Av_adeno_fibre PF06536.6 KLO13268.1 - 0.052 13.2 0.0 0.086 12.5 0.0 1.3 1 0 0 1 1 1 0 Avian adenovirus fibre Abhydrolase_6 PF12697.2 KLO13269.1 - 1.8e-12 47.6 0.0 2.9e-12 46.9 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KLO13269.1 - 0.021 14.5 0.0 0.045 13.5 0.0 1.7 1 1 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KLO13271.1 - 2.8e-13 50.2 0.0 4.2e-13 49.7 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KLO13271.1 - 1.5e-05 24.7 0.0 4.9e-05 23.1 0.0 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KLO13272.1 - 4.7e-14 52.8 0.1 7e-14 52.2 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KLO13272.1 - 0.00046 19.9 0.0 0.0012 18.5 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KLO13273.1 - 5.3e-16 59.1 0.0 6.7e-16 58.8 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KLO13273.1 - 0.00046 19.9 0.0 0.0006 19.5 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family RabGAP-TBC PF00566.13 KLO13275.1 - 3e-46 157.5 0.1 4.6e-46 156.9 0.0 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain EF-hand_7 PF13499.1 KLO13275.1 - 5.1e-06 26.5 8.3 0.00026 21.0 1.5 2.9 1 1 2 3 3 3 2 EF-hand domain pair EF-hand_6 PF13405.1 KLO13275.1 - 5.1e-06 25.9 3.4 0.0015 18.2 0.2 3.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.27 KLO13275.1 - 5.3e-05 22.2 0.7 0.0011 18.1 0.1 2.9 2 0 0 2 2 2 1 EF hand EF-hand_8 PF13833.1 KLO13275.1 - 0.00027 20.4 2.1 0.0021 17.6 0.2 3.0 2 1 1 3 3 3 1 EF-hand domain pair GRAM PF02893.15 KLO13275.1 - 0.00088 18.7 0.0 0.0022 17.4 0.0 1.7 1 0 0 1 1 1 1 GRAM domain EF-hand_5 PF13202.1 KLO13275.1 - 0.011 14.9 0.2 0.039 13.3 0.1 2.0 1 0 0 1 1 1 0 EF hand SPARC_Ca_bdg PF10591.4 KLO13275.1 - 0.13 12.3 0.2 0.38 10.8 0.1 1.8 1 0 0 1 1 1 0 Secreted protein acidic and rich in cysteine Ca binding region HSP70 PF00012.15 KLO13277.1 - 6.2e-05 21.1 0.0 0.00015 19.8 0.0 1.6 1 1 0 1 1 1 1 Hsp70 protein RicinB_lectin_2 PF14200.1 KLO13278.1 - 1.2e-08 35.2 8.3 0.0001 22.6 0.4 2.0 1 1 1 2 2 2 2 Ricin-type beta-trefoil lectin domain-like CarboxypepD_reg PF13620.1 KLO13278.1 - 0.58 10.2 3.8 3.2 7.8 0.3 2.9 1 1 0 2 2 2 0 Carboxypeptidase regulatory-like domain RicinB_lectin_2 PF14200.1 KLO13279.1 - 0.055 13.8 0.2 2.8 8.3 0.1 2.9 1 1 0 2 2 2 0 Ricin-type beta-trefoil lectin domain-like HSP70 PF00012.15 KLO13279.1 - 0.1 10.4 0.0 0.89 7.3 0.0 1.9 2 0 0 2 2 2 0 Hsp70 protein RicinB_lectin_2 PF14200.1 KLO13280.1 - 1.2e-05 25.6 7.2 4.4e-05 23.8 1.7 2.8 2 1 1 3 3 3 1 Ricin-type beta-trefoil lectin domain-like RicinB_lectin_2 PF14200.1 KLO13281.1 - 3.4e-08 33.8 7.5 1.8e-05 25.0 2.1 2.1 1 1 1 2 2 2 2 Ricin-type beta-trefoil lectin domain-like Y_Y_Y PF07495.8 KLO13281.1 - 0.026 14.2 0.7 0.49 10.1 0.0 2.7 3 0 0 3 3 3 0 Y_Y_Y domain Pkinase PF00069.20 KLO13282.1 - 1.3e-05 24.5 0.0 2.1e-05 23.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.9 KLO13282.1 - 0.0019 17.3 0.1 0.0037 16.3 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_Tyr PF07714.12 KLO13282.1 - 0.023 13.7 0.0 0.038 13.0 0.0 1.2 1 0 0 1 1 1 0 Protein tyrosine kinase 4HBT_2 PF13279.1 KLO13283.1 - 2.1e-16 60.4 0.0 3.1e-16 59.9 0.0 1.3 1 0 0 1 1 1 1 Thioesterase-like superfamily 4HBT PF03061.17 KLO13283.1 - 2.8e-06 27.3 0.0 5.7e-06 26.3 0.0 1.6 1 0 0 1 1 1 1 Thioesterase superfamily Acyl-ACP_TE PF01643.12 KLO13283.1 - 0.00012 21.1 0.2 0.0007 18.6 0.1 1.9 2 0 0 2 2 2 1 Acyl-ACP thioesterase PDCD2_C PF04194.8 KLO13284.1 - 6.9e-30 103.8 0.0 6.9e-30 103.8 0.0 3.2 3 1 0 3 3 3 1 Programmed cell death protein 2, C-terminal putative domain Herpes_UL56 PF04534.7 KLO13284.1 - 0.0062 16.2 0.2 0.25 11.0 0.0 2.4 2 0 0 2 2 2 1 Herpesvirus UL56 protein CDC45 PF02724.9 KLO13284.1 - 2.1 6.2 5.2 4.1 5.3 3.6 1.5 1 0 0 1 1 1 0 CDC45-like protein Herpes_LMP2 PF07415.6 KLO13284.1 - 7.2 5.0 10.2 10 4.5 7.1 1.1 1 0 0 1 1 1 0 Gammaherpesvirus latent membrane protein (LMP2) protein DNA_pol_phi PF04931.8 KLO13284.1 - 9.7 3.8 7.7 14 3.2 5.3 1.2 1 0 0 1 1 1 0 DNA polymerase phi PIG-F PF06699.6 KLO13285.1 - 1.8e-33 116.1 5.6 2.7e-33 115.5 3.8 1.3 1 0 0 1 1 1 1 GPI biosynthesis protein family Pig-F Reticulon PF02453.12 KLO13285.1 - 1.6 8.3 7.7 0.97 9.0 3.7 1.8 2 0 0 2 2 2 0 Reticulon O-antigen_lig PF13425.1 KLO13285.1 - 2.2 8.2 12.3 9.4 6.2 6.9 2.7 1 1 2 3 3 3 0 O-antigen ligase like membrane protein Cation_efflux PF01545.16 KLO13286.1 - 1.1e-61 208.4 5.3 1.1e-61 208.4 3.7 2.8 2 2 0 2 2 2 1 Cation efflux family Metal_resist PF13801.1 KLO13286.1 - 0.038 13.9 0.5 0.038 13.9 0.3 2.5 3 0 0 3 3 3 0 Heavy-metal resistance Ribosomal_L23 PF00276.15 KLO13287.1 - 9.6e-12 44.6 0.3 2.5e-11 43.3 0.0 1.8 2 0 0 2 2 2 1 Ribosomal protein L23 Flavin_Reduct PF01613.13 KLO13288.1 - 5.8e-29 100.9 0.1 7.6e-29 100.5 0.0 1.1 1 0 0 1 1 1 1 Flavin reductase like domain DNA_pol_B PF00136.16 KLO13289.1 - 1.2e-113 380.3 0.2 1.7e-113 379.9 0.1 1.1 1 0 0 1 1 1 1 DNA polymerase family B zf-DNA_Pol PF08996.5 KLO13289.1 - 1.3e-57 194.2 0.4 2.6e-57 193.2 0.3 1.5 1 0 0 1 1 1 1 DNA Polymerase alpha zinc finger DNA_pol_B_exo1 PF03104.14 KLO13289.1 - 1.3e-28 99.8 0.0 2.3e-28 99.0 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain DNA_pol_alpha_N PF12254.3 KLO13289.1 - 1e-16 60.5 7.9 2.5e-16 59.2 5.5 1.7 1 0 0 1 1 1 1 DNA polymerase alpha subunit p180 N terminal Metallophos PF00149.23 KLO13290.1 - 5.8e-09 35.6 0.0 1.9e-08 33.9 0.0 1.9 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 KLO13290.1 - 4.7e-05 23.2 0.0 9.7e-05 22.2 0.0 1.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Glyco_hydro_16 PF00722.16 KLO13291.1 - 1e-27 96.6 0.1 1.5e-27 96.0 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Fungal_trans PF04082.13 KLO13292.1 - 1.2e-20 73.4 1.1 2.6e-20 72.4 0.7 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KLO13292.1 - 3.3e-05 23.6 9.9 6.1e-05 22.8 6.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DHDPS PF00701.17 KLO13292.1 - 0.19 10.2 0.1 0.3 9.6 0.0 1.2 1 0 0 1 1 1 0 Dihydrodipicolinate synthetase family SRP-alpha_N PF04086.8 KLO13294.1 - 4.1 6.7 10.4 4.7 6.4 7.2 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Fungal_trans PF04082.13 KLO13295.1 - 6.8e-19 67.7 1.4 1.4e-18 66.7 1.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KLO13295.1 - 1.8e-05 24.5 12.6 3.3e-05 23.6 8.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF605 PF04652.11 KLO13295.1 - 0.087 12.2 18.7 0.15 11.4 13.0 1.3 1 0 0 1 1 1 0 Vta1 like TFIIA PF03153.8 KLO13295.1 - 4.2 7.1 14.3 6.6 6.5 9.9 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit RNA_pol_Rbc25 PF08292.7 KLO13296.1 - 6.5e-30 103.8 0.0 9.1e-30 103.3 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase III subunit Rpc25 SHS2_Rpb7-N PF03876.12 KLO13296.1 - 3e-20 72.1 0.1 5e-20 71.3 0.0 1.4 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 Mito_carr PF00153.22 KLO13297.1 - 1.3e-65 217.1 0.2 2.2e-20 72.1 0.0 3.3 3 1 0 3 3 3 3 Mitochondrial carrier protein MMR_HSR1 PF01926.18 KLO13298.1 - 4.1e-13 49.3 0.0 5.4e-13 48.9 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.18 KLO13298.1 - 4.1e-06 26.7 0.0 0.0015 18.3 0.0 2.4 1 1 1 2 2 2 2 Dynamin family DUF258 PF03193.11 KLO13298.1 - 0.0039 16.3 0.0 0.007 15.5 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 FeoB_N PF02421.13 KLO13298.1 - 0.0041 16.3 0.0 0.0067 15.7 0.0 1.3 1 0 0 1 1 1 1 Ferrous iron transport protein B AIG1 PF04548.11 KLO13298.1 - 0.018 14.1 0.0 0.027 13.5 0.0 1.4 1 1 0 1 1 1 0 AIG1 family Miro PF08477.8 KLO13298.1 - 0.022 15.2 0.0 0.049 14.1 0.0 1.6 1 0 0 1 1 1 0 Miro-like protein Septin PF00735.13 KLO13298.1 - 0.051 12.5 0.1 1.9 7.4 0.0 2.5 2 1 0 2 2 2 0 Septin AAA_29 PF13555.1 KLO13298.1 - 0.052 13.0 0.0 0.1 12.1 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_tran PF00005.22 KLO13298.1 - 0.065 13.5 0.2 0.46 10.7 0.0 2.0 2 0 0 2 2 2 0 ABC transporter DUF1351 PF07083.6 KLO13298.1 - 0.098 12.2 0.0 0.14 11.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1351) FtsK_SpoIIIE PF01580.13 KLO13298.1 - 0.1 12.0 0.1 0.18 11.2 0.1 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family GTP_EFTU PF00009.22 KLO13298.1 - 0.12 11.8 0.0 0.85 9.0 0.0 2.2 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain F-box-like PF12937.2 KLO13299.1 - 9.6e-05 22.0 0.3 0.00037 20.1 0.0 2.2 2 0 0 2 2 2 1 F-box-like IncA PF04156.9 KLO13300.1 - 1.7 8.2 7.0 7.5 6.1 3.6 2.3 2 1 0 2 2 2 0 IncA protein TMF_DNA_bd PF12329.3 KLO13300.1 - 1.9 8.3 9.1 0.48 10.2 1.1 3.1 2 1 1 3 3 3 0 TATA element modulatory factor 1 DNA binding DUF1771 PF08590.5 KLO13301.1 - 1e-14 54.2 8.8 2.5e-14 53.0 6.1 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1771) zf-CCCH PF00642.19 KLO13301.1 - 3.7e-09 36.0 7.8 3.5e-06 26.5 0.6 2.5 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Smr PF01713.16 KLO13301.1 - 0.00056 20.0 0.0 0.0017 18.4 0.0 1.9 1 0 0 1 1 1 1 Smr domain UBA PF00627.26 KLO13301.1 - 0.062 13.1 0.0 0.14 12.0 0.0 1.6 1 0 0 1 1 1 0 UBA/TS-N domain zf-C3H1 PF10650.4 KLO13301.1 - 0.079 12.4 1.6 7.6 6.1 0.1 2.4 2 0 0 2 2 2 0 Putative zinc-finger domain PqqD PF05402.7 KLO13301.1 - 0.42 10.6 2.4 4.8 7.2 0.3 2.4 2 0 0 2 2 2 0 Coenzyme PQQ synthesis protein D (PqqD) zf-CCCH_2 PF14608.1 KLO13301.1 - 5.8 7.0 6.2 1.6 8.8 0.4 2.3 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type HD_3 PF13023.1 KLO13303.1 - 4.7e-39 133.7 0.1 6.1e-39 133.4 0.1 1.1 1 0 0 1 1 1 1 HD domain HD PF01966.17 KLO13303.1 - 3.5e-07 30.2 0.1 7.3e-07 29.2 0.1 1.6 1 1 0 1 1 1 1 HD domain AICARFT_IMPCHas PF01808.13 KLO13304.1 - 6.3e-110 367.1 0.0 9.9e-110 366.5 0.0 1.3 1 0 0 1 1 1 1 AICARFT/IMPCHase bienzyme MGS PF02142.17 KLO13304.1 - 1.9e-24 85.4 0.0 3.6e-24 84.5 0.0 1.5 1 0 0 1 1 1 1 MGS-like domain Methyltransf_28 PF02636.12 KLO13305.1 - 0.095 12.0 0.0 7.9 5.7 0.0 2.2 1 1 1 2 2 2 0 Putative S-adenosyl-L-methionine-dependent methyltransferase Pkinase PF00069.20 KLO13306.1 - 1.6e-35 122.5 0.0 2e-35 122.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KLO13306.1 - 2e-34 118.8 0.0 2.6e-34 118.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 KLO13306.1 - 8.1e-05 22.4 0.0 0.00017 21.4 0.0 1.5 2 0 0 2 2 2 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 KLO13306.1 - 0.02 13.7 0.1 0.028 13.2 0.0 1.1 1 0 0 1 1 1 0 Seadornavirus VP7 Fructosamin_kin PF03881.9 KLO13306.1 - 0.093 11.6 0.0 0.14 11.0 0.0 1.2 1 0 0 1 1 1 0 Fructosamine kinase MFS_1 PF07690.11 KLO13307.1 - 4.2e-38 130.9 34.2 4.2e-38 130.9 23.7 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KLO13307.1 - 4.8e-07 28.7 34.4 2.6e-06 26.2 10.3 3.1 2 1 0 2 2 2 2 Sugar (and other) transporter MFS_3 PF05977.8 KLO13307.1 - 2.4e-05 22.6 2.1 3.5e-05 22.1 1.4 1.2 1 0 0 1 1 1 1 Transmembrane secretion effector HAMP PF00672.20 KLO13309.1 - 0.037 14.2 0.3 0.097 12.8 0.2 1.7 1 1 0 1 1 1 0 HAMP domain DUF347 PF03988.7 KLO13313.1 - 0.34 10.8 1.7 0.4 10.6 0.1 2.0 2 0 0 2 2 2 0 Repeat of Unknown Function (DUF347) DAP10 PF07213.6 KLO13315.1 - 0.0077 15.9 0.3 0.017 14.9 0.2 1.5 1 0 0 1 1 1 1 DAP10 membrane protein HlyIII PF03006.15 KLO13316.1 - 1.6e-54 184.7 19.4 1.9e-54 184.4 13.4 1.1 1 0 0 1 1 1 1 Haemolysin-III related Rootletin PF15035.1 KLO13316.1 - 0.069 13.1 0.2 0.1 12.5 0.1 1.1 1 0 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion GATase_2 PF00310.16 KLO13316.1 - 0.072 11.7 0.0 0.11 11.2 0.0 1.1 1 0 0 1 1 1 0 Glutamine amidotransferases class-II MFS_1 PF07690.11 KLO13319.1 - 2.2e-23 82.5 29.5 2e-20 72.8 4.0 2.2 2 0 0 2 2 2 2 Major Facilitator Superfamily STE3 PF02076.10 KLO13321.1 - 2.2e-46 158.2 13.5 3e-46 157.7 9.4 1.1 1 0 0 1 1 1 1 Pheromone A receptor Pro_CA PF00484.14 KLO13323.1 - 8.9e-15 55.0 0.0 1.2e-14 54.6 0.0 1.1 1 0 0 1 1 1 1 Carbonic anhydrase Apolipoprotein PF01442.13 KLO13324.1 - 0.00016 21.2 3.7 0.00016 21.2 2.6 2.2 1 1 1 2 2 2 2 Apolipoprotein A1/A4/E domain Prominin PF05478.6 KLO13324.1 - 0.044 11.3 1.1 0.067 10.7 0.8 1.2 1 0 0 1 1 1 0 Prominin Exonuc_VII_L PF02601.10 KLO13324.1 - 0.051 12.7 3.4 0.069 12.3 0.9 2.0 1 1 1 2 2 2 0 Exonuclease VII, large subunit Z1 PF10593.4 KLO13324.1 - 0.098 11.8 3.4 0.1 11.8 1.7 1.5 1 1 0 1 1 1 0 Z1 domain ANTH PF07651.11 KLO13324.1 - 0.11 11.1 4.7 0.2 10.3 3.2 1.4 1 1 0 1 1 1 0 ANTH domain Lipoprotein_6 PF01441.14 KLO13324.1 - 0.15 11.9 0.5 0.34 10.7 0.1 1.8 2 0 0 2 2 2 0 Lipoprotein AT_hook PF02178.14 KLO13324.1 - 0.25 11.1 5.6 0.62 9.9 3.9 1.7 1 0 0 1 1 1 0 AT hook motif DUF2937 PF11157.3 KLO13324.1 - 0.33 10.2 3.0 0.52 9.6 0.1 2.3 2 1 1 3 3 3 0 Protein of unknown function (DUF2937) OmpH PF03938.9 KLO13324.1 - 0.4 10.6 12.7 2.4 8.0 2.3 3.0 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) DUF1664 PF07889.7 KLO13324.1 - 0.93 9.2 7.8 0.43 10.3 0.9 2.7 1 1 3 4 4 4 0 Protein of unknown function (DUF1664) Fzo_mitofusin PF04799.8 KLO13324.1 - 1.1 8.6 5.2 0.92 8.8 0.4 2.4 2 1 0 2 2 2 0 fzo-like conserved region DUF883 PF05957.8 KLO13324.1 - 1.7 9.0 7.8 4 7.8 0.2 3.2 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF883) HSBP1 PF06825.7 KLO13324.1 - 3.7 7.1 13.5 0.35 10.4 3.1 3.3 3 1 1 4 4 4 0 Heat shock factor binding protein 1 zf-C3HC4_3 PF13920.1 KLO13325.1 - 4.6e-13 48.6 8.1 4.6e-13 48.6 5.6 2.6 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KLO13325.1 - 1.6e-07 31.2 8.6 1.6e-07 31.2 6.0 2.6 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) FYVE PF01363.16 KLO13325.1 - 7.3e-07 29.0 8.2 7.3e-07 29.0 5.7 2.8 2 1 0 2 2 2 1 FYVE zinc finger zf-RING_2 PF13639.1 KLO13325.1 - 4.7e-06 26.3 7.0 4.7e-06 26.3 4.8 2.7 2 1 0 2 2 1 1 Ring finger domain zf-C3HC4 PF00097.20 KLO13325.1 - 2.2e-05 24.0 8.3 2.2e-05 24.0 5.8 3.0 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KLO13325.1 - 0.0025 17.4 6.2 0.0025 17.4 4.3 2.5 2 0 0 2 2 2 1 zinc-RING finger domain Prok-RING_4 PF14447.1 KLO13325.1 - 0.0028 17.1 2.2 0.0028 17.1 1.5 2.3 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 TFIIF_alpha PF05793.7 KLO13325.1 - 0.0053 15.1 6.2 0.012 14.0 4.3 1.5 1 0 0 1 1 1 1 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) zf-P11 PF03854.9 KLO13325.1 - 0.0061 15.9 3.9 0.0061 15.9 2.7 2.4 2 1 1 3 3 3 1 P-11 zinc finger FYVE_2 PF02318.11 KLO13325.1 - 0.0061 16.4 3.5 0.0061 16.4 2.5 3.4 3 1 1 4 4 2 1 FYVE-type zinc finger UPF0547 PF10571.4 KLO13325.1 - 0.075 12.7 13.5 0.18 11.4 0.8 3.4 2 1 0 2 2 2 0 Uncharacterised protein family UPF0547 zf-UDP PF14569.1 KLO13325.1 - 0.2 11.4 9.8 0.069 12.9 1.2 2.9 2 0 0 2 2 2 0 Zinc-binding RING-finger GBP_C PF02841.9 KLO13325.1 - 1.6 7.8 16.8 2.6 7.1 11.6 1.2 1 0 0 1 1 1 0 Guanylate-binding protein, C-terminal domain zf-C3HC4_4 PF15227.1 KLO13325.1 - 5.7 6.8 17.7 8.5 6.3 5.3 3.3 3 0 0 3 3 3 0 zinc finger of C3HC4-type, RING MBA1 PF07961.6 KLO13326.1 - 0.00083 18.2 0.0 0.0014 17.5 0.0 1.4 1 1 0 1 1 1 1 MBA1-like protein FMO-like PF00743.14 KLO13327.1 - 1.9e-34 118.8 0.0 1.3e-23 82.9 0.0 2.4 1 1 1 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 KLO13327.1 - 5.9e-20 72.1 0.0 2.6e-19 70.0 0.0 2.0 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 KLO13327.1 - 6.3e-08 32.5 4.8 0.00018 21.3 0.3 3.9 2 2 0 3 3 3 2 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 KLO13327.1 - 3.3e-06 27.1 0.0 2.6e-05 24.2 0.0 2.2 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 KLO13327.1 - 1.6e-05 24.0 0.3 0.00028 19.9 0.0 2.5 2 1 1 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.19 KLO13327.1 - 3.6e-05 22.8 0.1 1.1 8.1 0.0 3.5 3 0 0 3 3 3 3 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KLO13327.1 - 0.00025 20.9 0.1 0.0025 17.7 0.0 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.9 KLO13327.1 - 0.0011 17.5 1.0 1.3 7.4 0.0 3.2 3 1 1 4 4 4 2 HI0933-like protein Sec20 PF03908.8 KLO13328.1 - 6.9e-17 60.9 4.6 1.7e-16 59.6 1.3 2.4 2 0 0 2 2 2 1 Sec20 Use1 PF09753.4 KLO13328.1 - 0.00083 18.8 8.1 0.0016 17.9 5.6 1.5 1 1 0 1 1 1 1 Membrane fusion protein Use1 KxDL PF10241.4 KLO13328.1 - 0.00085 19.1 0.4 0.00085 19.1 0.3 2.4 2 1 1 3 3 3 1 Uncharacterized conserved protein MRP-S31 PF15433.1 KLO13328.1 - 0.28 10.5 4.4 0.42 9.9 3.0 1.2 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S31 Baculo_11_kDa PF06143.6 KLO13328.1 - 0.45 9.9 4.2 1.3 8.3 2.9 1.8 1 1 0 1 1 1 0 Baculovirus 11 kDa family Phage_Gp23 PF10669.4 KLO13328.1 - 7.2 6.7 16.4 4.3 7.4 1.9 3.2 2 1 1 3 3 3 0 Protein gp23 (Bacteriophage A118) MR_MLE_C PF13378.1 KLO13329.1 - 4.2e-34 116.8 0.1 2.1e-33 114.5 0.0 2.0 2 0 0 2 2 2 1 Enolase C-terminal domain-like MR_MLE_N PF02746.11 KLO13329.1 - 2.2e-24 85.6 0.0 4.1e-24 84.8 0.0 1.4 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain MR_MLE PF01188.16 KLO13329.1 - 5.3e-10 39.6 0.0 1.3e-09 38.4 0.0 1.6 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain DUF3983 PF13137.1 KLO13329.1 - 0.14 11.8 1.0 0.37 10.5 0.7 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3983) DUF221 PF02714.10 KLO13330.1 - 3.9e-105 351.3 19.6 3.9e-105 351.3 13.6 1.9 2 0 0 2 2 2 1 Domain of unknown function DUF221 RSN1_TM PF13967.1 KLO13330.1 - 1.5e-35 122.0 4.6 1.5e-35 122.0 3.2 2.1 2 0 0 2 2 2 1 Late exocytosis, associated with Golgi transport DUF4463 PF14703.1 KLO13330.1 - 7.9e-15 55.1 2.3 1.5e-14 54.2 1.6 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4463) DUF3779 PF12621.3 KLO13330.1 - 3.7e-08 33.1 0.1 9.8e-06 25.3 0.0 2.5 1 1 0 1 1 1 1 Phosphate metabolism protein Syntaxin-6_N PF09177.6 KLO13331.1 - 9.6e-24 83.6 0.6 9.6e-24 83.6 0.4 2.9 2 1 1 3 3 3 1 Syntaxin 6, N-terminal SNARE PF05739.14 KLO13331.1 - 2.3e-13 49.6 2.9 2.3e-13 49.6 2.0 2.4 3 0 0 3 3 2 1 SNARE domain DUF3584 PF12128.3 KLO13331.1 - 0.00026 18.5 6.5 0.00044 17.7 4.4 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF3584) Bacillus_HBL PF05791.6 KLO13331.1 - 0.00083 18.7 6.4 0.1 11.9 0.0 2.6 3 1 0 3 3 2 2 Bacillus haemolytic enterotoxin (HBL) Use1 PF09753.4 KLO13331.1 - 0.006 16.0 1.9 0.012 15.0 1.3 1.6 1 1 0 1 1 1 1 Membrane fusion protein Use1 TBPIP PF07106.8 KLO13331.1 - 0.014 14.9 4.9 0.7 9.4 0.0 2.4 2 0 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Laminin_I PF06008.9 KLO13331.1 - 0.015 14.6 10.9 0.054 12.7 0.6 2.1 2 0 0 2 2 2 0 Laminin Domain I CENP-H PF05837.7 KLO13331.1 - 0.023 14.8 6.7 1.3 9.1 0.2 2.7 3 1 0 3 3 2 0 Centromere protein H (CENP-H) DUF536 PF04394.9 KLO13331.1 - 0.024 14.3 0.5 0.024 14.3 0.3 2.5 2 0 0 2 2 2 0 Protein of unknown function, DUF536 Fusion_gly PF00523.13 KLO13331.1 - 0.031 12.3 0.5 0.05 11.6 0.3 1.4 1 0 0 1 1 1 0 Fusion glycoprotein F0 GP41 PF00517.12 KLO13331.1 - 0.038 13.5 4.6 0.044 13.3 1.2 2.3 2 1 1 3 3 3 0 Retroviral envelope protein TMF_DNA_bd PF12329.3 KLO13331.1 - 0.057 13.2 10.4 0.36 10.6 1.0 3.0 2 1 1 3 3 3 0 TATA element modulatory factor 1 DNA binding Prominin PF05478.6 KLO13331.1 - 0.06 10.8 2.2 0.092 10.2 0.3 1.9 2 0 0 2 2 2 0 Prominin Viral_DNA_bp PF00747.12 KLO13331.1 - 0.094 9.9 0.7 0.12 9.5 0.5 1.1 1 0 0 1 1 1 0 ssDNA binding protein Reo_sigmaC PF04582.7 KLO13331.1 - 0.1 11.7 3.5 3.1 6.9 0.2 2.2 2 0 0 2 2 2 0 Reovirus sigma C capsid protein Laminin_II PF06009.7 KLO13331.1 - 0.12 12.1 5.1 4 7.1 0.4 2.3 2 0 0 2 2 2 0 Laminin Domain II Spc7 PF08317.6 KLO13331.1 - 0.14 10.8 9.8 0.72 8.4 0.1 2.2 2 0 0 2 2 2 0 Spc7 kinetochore protein Snapin_Pallidin PF14712.1 KLO13331.1 - 0.14 12.4 8.2 0.48 10.7 0.3 3.1 2 1 2 4 4 4 0 Snapin/Pallidin Atg14 PF10186.4 KLO13331.1 - 0.14 11.0 7.8 0.19 10.6 0.8 2.4 2 1 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 FliJ PF02050.11 KLO13331.1 - 0.23 11.5 10.9 4.7 7.2 0.1 2.8 2 1 0 2 2 2 0 Flagellar FliJ protein FlaC_arch PF05377.6 KLO13331.1 - 0.26 11.2 7.2 19 5.2 0.1 4.2 3 2 1 4 4 4 0 Flagella accessory protein C (FlaC) SlyX PF04102.7 KLO13331.1 - 0.3 11.5 9.0 1.2 9.6 1.4 3.6 3 1 1 4 4 4 0 SlyX LXG PF04740.7 KLO13331.1 - 0.44 10.3 6.1 2.6 7.7 2.1 2.4 2 0 0 2 2 2 0 LXG domain of WXG superfamily DUF1640 PF07798.6 KLO13331.1 - 0.83 9.6 7.1 4.3 7.3 1.5 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF1640) MAD PF05557.8 KLO13331.1 - 1.1 7.2 12.8 2.3 6.1 0.4 2.1 2 0 0 2 2 2 0 Mitotic checkpoint protein AAA_13 PF13166.1 KLO13331.1 - 1.2 7.5 4.6 2.3 6.5 0.4 2.0 2 0 0 2 2 2 0 AAA domain DUF745 PF05335.8 KLO13331.1 - 1.4 8.4 8.9 4.8 6.6 1.1 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF745) HisKA_3 PF07730.8 KLO13331.1 - 2.1 8.7 10.8 1.5 9.1 0.3 3.4 2 1 1 3 3 3 0 Histidine kinase Seryl_tRNA_N PF02403.17 KLO13331.1 - 2.6 8.0 8.3 2.8 7.9 0.2 2.6 2 1 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain CENP-F_leu_zip PF10473.4 KLO13331.1 - 3.9 7.3 14.4 0.32 10.8 0.4 2.6 3 0 0 3 3 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 MscS_porin PF12795.2 KLO13331.1 - 5.3 6.2 16.4 0.076 12.3 2.4 2.3 2 0 0 2 2 2 0 Mechanosensitive ion channel porin domain EMP24_GP25L PF01105.19 KLO13331.1 - 9.5 5.8 9.3 20 4.8 0.2 2.6 2 1 0 2 2 2 0 emp24/gp25L/p24 family/GOLD Sir1 PF11603.3 KLO13332.1 - 0.029 14.5 0.2 0.045 13.9 0.1 1.2 1 0 0 1 1 1 0 Regulatory protein Sir1 p450 PF00067.17 KLO13333.1 - 1.8e-56 191.6 0.0 2.6e-56 191.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 ESPR PF13018.1 KLO13333.1 - 0.044 13.4 0.2 0.044 13.4 0.1 2.4 3 0 0 3 3 3 0 Extended Signal Peptide of Type V secretion system ADH_N PF08240.7 KLO13334.1 - 8.6e-30 102.7 1.6 1.5e-29 101.9 1.1 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KLO13334.1 - 1.7e-27 95.5 0.5 2.8e-27 94.8 0.3 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 KLO13334.1 - 7.2e-06 26.9 0.3 1.2e-05 26.1 0.2 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase CBM_1 PF00734.13 KLO13335.1 - 5.1e-13 48.4 9.2 5.1e-13 48.4 6.4 2.6 2 0 0 2 2 2 1 Fungal cellulose binding domain PhoPQ_related PF10142.4 KLO13335.1 - 0.13 10.6 0.0 0.21 10.0 0.0 1.2 1 0 0 1 1 1 0 PhoPQ-activated pathogenicity-related protein Helicase_C_3 PF13625.1 KLO13336.1 - 1.7e-28 98.9 0.0 1.7e-26 92.4 0.0 2.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 KLO13336.1 - 2.7e-14 53.4 1.2 3.2e-14 53.1 0.0 1.7 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit SNF2_N PF00176.18 KLO13336.1 - 7.2e-13 47.9 0.2 1.2e-12 47.2 0.1 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 KLO13336.1 - 2.6e-11 43.2 0.1 6.7e-11 41.9 0.1 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-MYND PF01753.13 KLO13337.1 - 1.4e-07 31.2 11.6 2.9e-07 30.2 8.1 1.5 1 0 0 1 1 1 1 MYND finger zf-MYND PF01753.13 KLO13338.1 - 5.9e-09 35.6 13.1 1e-08 34.9 9.1 1.4 1 0 0 1 1 1 1 MYND finger RseC_MucC PF04246.7 KLO13338.1 - 0.59 9.7 4.1 1.2 8.6 2.9 1.4 1 0 0 1 1 1 0 Positive regulator of sigma(E), RseC/MucC zf-MYND PF01753.13 KLO13339.1 - 2.2e-08 33.8 12.3 2.2e-08 33.8 8.5 1.6 2 0 0 2 2 2 1 MYND finger MFS_1 PF07690.11 KLO13341.1 - 1.8e-30 105.8 26.9 6.9e-30 103.9 17.8 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1228 PF06779.9 KLO13341.1 - 0.018 15.0 1.4 5.7 7.0 0.1 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF1228) NfeD PF01957.13 KLO13341.1 - 0.94 9.6 9.9 1.8 8.6 1.3 3.0 2 1 1 3 3 3 0 NfeD-like C-terminal, partner-binding PCI PF01399.22 KLO13342.1 - 4.6e-21 75.1 0.3 1.6e-20 73.3 0.0 2.1 3 0 0 3 3 3 1 PCI domain Rpn3_C PF08375.6 KLO13342.1 - 1.7e-17 63.5 0.2 4.1e-17 62.3 0.2 1.6 1 0 0 1 1 1 1 Proteasome regulatory subunit C-terminal TPR_2 PF07719.12 KLO13342.1 - 0.00027 20.6 1.4 0.15 12.0 0.3 2.8 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.1 KLO13342.1 - 0.0004 20.2 4.6 0.028 14.3 0.4 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.1 KLO13342.1 - 0.059 13.0 0.5 1.6 8.4 0.2 2.6 2 0 0 2 2 2 0 TPR repeat PCI_Csn8 PF10075.4 KLO13342.1 - 0.059 13.1 0.0 0.12 12.2 0.0 1.5 1 0 0 1 1 1 0 COP9 signalosome, subunit CSN8 TPR_16 PF13432.1 KLO13342.1 - 7.9 7.2 10.0 2.3 8.9 0.1 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat F-box-like PF12937.2 KLO13343.1 - 8.6e-08 31.7 3.0 1.3e-07 31.2 0.2 2.7 3 0 0 3 3 3 1 F-box-like DUF2471 PF10616.4 KLO13343.1 - 0.0056 16.8 0.0 0.0099 16.0 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2471) Sec23_trunk PF04811.10 KLO13344.1 - 2.2e-71 240.0 0.0 4.1e-71 239.1 0.0 1.4 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.10 KLO13344.1 - 1.1e-24 85.8 0.1 2.7e-24 84.5 0.1 1.8 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Sec23_BS PF08033.7 KLO13344.1 - 1.5e-17 63.9 0.0 3.7e-17 62.6 0.0 1.7 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.10 KLO13344.1 - 5.2e-17 61.1 5.3 1.1e-16 60.0 3.7 1.6 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.17 KLO13344.1 - 2.8e-07 30.1 0.0 6.1e-07 29.0 0.0 1.6 1 0 0 1 1 1 1 Gelsolin repeat WW PF00397.21 KLO13344.1 - 4.1e-05 23.3 1.7 4.1e-05 23.3 1.2 2.2 2 0 0 2 2 2 1 WW domain SecY PF00344.15 KLO13345.1 - 0.77 8.6 12.2 0.24 10.3 0.5 2.8 1 1 1 2 2 2 0 SecY translocase MFS_1 PF07690.11 KLO13346.1 - 6.5e-21 74.4 62.1 2.8e-19 69.0 19.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1228 PF06779.9 KLO13346.1 - 0.0032 17.4 9.0 0.15 12.0 0.2 3.4 3 0 0 3 3 3 2 Protein of unknown function (DUF1228) PITH PF06201.8 KLO13347.1 - 1.3e-34 119.2 0.0 1.6e-34 118.8 0.0 1.1 1 0 0 1 1 1 1 PITH domain Ribosomal_S5_C PF03719.10 KLO13348.1 - 6.7e-19 66.9 0.3 2.3e-18 65.2 0.1 2.0 2 0 0 2 2 2 1 Ribosomal protein S5, C-terminal domain Ribosomal_S5 PF00333.15 KLO13348.1 - 6.2e-13 48.2 0.1 2e-12 46.6 0.1 1.8 2 0 0 2 2 2 1 Ribosomal protein S5, N-terminal domain Stn1 PF10451.4 KLO13349.1 - 0.00045 19.1 1.8 0.023 13.5 0.2 3.1 3 0 0 3 3 3 2 Telomere regulation protein Stn1 tRNA_anti-codon PF01336.20 KLO13349.1 - 0.018 14.8 0.6 0.064 13.1 0.4 1.9 1 1 0 1 1 1 0 OB-fold nucleic acid binding domain LIM PF00412.17 KLO13350.1 - 3.1e-19 68.7 26.7 1.6e-11 44.0 1.0 5.0 5 1 0 5 5 5 4 LIM domain MFS_1 PF07690.11 KLO13351.1 - 1.5e-37 129.1 50.5 2.2e-37 128.5 33.3 2.3 2 1 0 2 2 2 1 Major Facilitator Superfamily L1R_F9L PF02442.12 KLO13351.1 - 0.019 14.4 0.5 0.063 12.7 0.4 1.9 1 0 0 1 1 1 0 Lipid membrane protein of large eukaryotic DNA viruses DUF1220 PF06758.8 KLO13351.1 - 0.16 11.8 0.4 0.41 10.4 0.3 1.7 1 0 0 1 1 1 0 Repeat of unknown function (DUF1220) DUF1509 PF07420.6 KLO13352.1 - 0.09 12.0 0.1 0.098 11.9 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1509) DUF939_C PF11728.3 KLO13352.1 - 0.1 12.3 0.1 0.14 11.9 0.1 1.3 1 1 0 1 1 1 0 DUF939 C-terminal domain Coatomer_WDAD PF04053.9 KLO13353.1 - 1.8e-140 468.6 0.1 3.9e-140 467.5 0.0 1.5 2 0 0 2 2 2 1 Coatomer WD associated region COPI_C PF06957.6 KLO13353.1 - 1.4e-97 326.9 0.0 1.9e-97 326.4 0.0 1.1 1 0 0 1 1 1 1 Coatomer (COPI) alpha subunit C-terminus WD40 PF00400.27 KLO13353.1 - 1.5e-57 189.5 12.4 5.4e-10 38.7 0.2 8.9 9 0 0 9 9 9 6 WD domain, G-beta repeat TPR_16 PF13432.1 KLO13353.1 - 0.01 16.5 5.9 2.2 9.0 0.6 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat Apc4_WD40 PF12894.2 KLO13353.1 - 0.015 14.8 0.0 48 3.5 0.0 4.6 5 0 0 5 5 5 0 Anaphase-promoting complex subunit 4 WD40 domain Clathrin PF00637.15 KLO13353.1 - 0.015 14.9 0.1 0.11 12.1 0.1 2.4 4 0 0 4 4 4 0 Region in Clathrin and VPS Nup160 PF11715.3 KLO13353.1 - 0.017 13.2 1.4 0.36 8.8 0.0 2.9 1 1 1 3 3 3 0 Nucleoporin Nup120/160 eIF2A PF08662.6 KLO13353.1 - 0.072 12.7 0.0 12 5.5 0.0 3.3 2 1 1 3 3 3 0 Eukaryotic translation initiation factor eIF2A TPR_2 PF07719.12 KLO13353.1 - 0.47 10.5 2.5 14 5.9 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.1 KLO13353.1 - 1.5 9.6 6.0 8.1 7.3 0.7 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat Fungal_trans PF04082.13 KLO13354.1 - 6e-09 35.1 0.1 1.1e-08 34.3 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KLO13354.1 - 2.2e-06 27.4 11.8 5.4e-06 26.2 8.2 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Dimer_Tnp_hAT PF05699.9 KLO13354.1 - 0.008 15.7 0.0 0.029 14.0 0.0 1.9 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region Fmp27_WPPW PF10359.4 KLO13354.1 - 0.066 11.6 0.5 0.097 11.0 0.3 1.2 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain Pkinase_Tyr PF07714.12 KLO13355.1 - 6e-34 117.2 0.0 1e-33 116.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 KLO13355.1 - 1.3e-32 113.0 0.0 2.4e-32 112.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain KH_1 PF00013.24 KLO13355.1 - 0.00042 19.8 0.1 0.00081 18.9 0.1 1.4 1 0 0 1 1 1 1 KH domain KH_3 PF13014.1 KLO13355.1 - 0.083 12.5 0.0 0.18 11.5 0.0 1.6 1 0 0 1 1 1 0 KH domain WAC_Acf1_DNA_bd PF10537.4 KLO13356.1 - 0.13 12.4 0.0 0.17 12.0 0.0 1.2 1 0 0 1 1 1 0 ATP-utilising chromatin assembly and remodelling N-terminal Phlebovirus_G1 PF07243.6 KLO13357.1 - 0.37 8.8 0.4 0.56 8.2 0.3 1.2 1 0 0 1 1 1 0 Phlebovirus glycoprotein G1 DUF4229 PF14012.1 KLO13357.1 - 2.1 8.2 10.0 2.7 7.9 0.3 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF4229) WW PF00397.21 KLO13358.1 - 0.0013 18.5 0.3 0.0033 17.2 0.2 1.7 1 0 0 1 1 1 1 WW domain DUF2457 PF10446.4 KLO13359.1 - 0.028 13.1 12.6 0.028 13.1 8.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Sporozoite_P67 PF05642.6 KLO13359.1 - 0.063 11.1 9.0 0.066 11.0 6.3 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Cytochrome-c551 PF10643.4 KLO13359.1 - 0.19 10.9 0.5 0.24 10.6 0.3 1.1 1 0 0 1 1 1 0 Photosystem P840 reaction-centre cytochrome c-551 FLO_LFY PF01698.11 KLO13359.1 - 0.28 10.0 3.5 0.31 9.8 2.4 1.0 1 0 0 1 1 1 0 Floricaula / Leafy protein Nop14 PF04147.7 KLO13359.1 - 0.28 9.0 15.0 0.29 9.0 10.4 1.0 1 0 0 1 1 1 0 Nop14-like family Nucleoplasmin PF03066.10 KLO13359.1 - 0.47 9.9 13.7 0.52 9.8 9.5 1.2 1 0 0 1 1 1 0 Nucleoplasmin RNA_pol_3_Rpc31 PF11705.3 KLO13359.1 - 1.2 9.0 13.4 1.4 8.8 9.3 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 TRAP_alpha PF03896.11 KLO13359.1 - 1.2 8.0 7.1 1.4 7.8 4.9 1.3 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit CENP-B_dimeris PF09026.5 KLO13359.1 - 1.7 8.9 21.5 0.094 12.9 11.0 1.8 2 0 0 2 2 2 0 Centromere protein B dimerisation domain Retinal PF15449.1 KLO13359.1 - 1.7 6.1 7.2 1.8 6.1 5.0 1.0 1 0 0 1 1 1 0 Retinal protein BUD22 PF09073.5 KLO13359.1 - 2.3 7.2 13.8 2.6 6.9 9.5 1.1 1 0 0 1 1 1 0 BUD22 SDA1 PF05285.7 KLO13359.1 - 3 7.0 13.8 3.1 7.0 9.6 1.1 1 0 0 1 1 1 0 SDA1 BAF1_ABF1 PF04684.8 KLO13359.1 - 3.4 6.4 8.4 4.1 6.1 5.8 1.0 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor NOA36 PF06524.7 KLO13359.1 - 3.5 6.7 13.3 4 6.5 9.2 1.1 1 0 0 1 1 1 0 NOA36 protein Myc_N PF01056.13 KLO13359.1 - 3.9 6.5 9.9 4.5 6.3 6.9 1.2 1 0 0 1 1 1 0 Myc amino-terminal region DUF1510 PF07423.6 KLO13359.1 - 7.3 5.8 12.6 8.7 5.6 8.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) MYCBPAP PF14646.1 KLO13361.1 - 0.071 11.8 3.1 0.088 11.5 2.1 1.0 1 0 0 1 1 1 0 MYCBP-associated protein family Retinal PF15449.1 KLO13361.1 - 0.071 10.7 2.1 0.08 10.5 1.4 1.0 1 0 0 1 1 1 0 Retinal protein DUF2457 PF10446.4 KLO13361.1 - 0.088 11.5 12.4 0.11 11.1 8.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Astro_capsid PF03115.9 KLO13361.1 - 0.11 10.7 3.4 0.14 10.4 2.4 1.0 1 0 0 1 1 1 0 Astrovirus capsid protein precursor CDC45 PF02724.9 KLO13361.1 - 0.21 9.5 5.1 0.22 9.5 3.5 1.2 1 0 0 1 1 1 0 CDC45-like protein FLO_LFY PF01698.11 KLO13361.1 - 0.31 9.8 2.5 0.36 9.6 1.7 1.0 1 0 0 1 1 1 0 Floricaula / Leafy protein NOA36 PF06524.7 KLO13361.1 - 0.42 9.8 8.7 0.5 9.5 6.0 1.1 1 0 0 1 1 1 0 NOA36 protein Nucleoplasmin PF03066.10 KLO13361.1 - 0.49 9.9 8.9 0.66 9.4 6.2 1.3 1 0 0 1 1 1 0 Nucleoplasmin BTV_NS2 PF04514.7 KLO13361.1 - 0.66 8.7 7.6 0.78 8.5 5.3 1.0 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 PBP1_TM PF14812.1 KLO13361.1 - 3.3 8.0 8.7 6.5 7.1 6.0 1.4 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Sigma70_ner PF04546.8 KLO13361.1 - 4.8 6.7 8.7 6.3 6.3 6.1 1.2 1 0 0 1 1 1 0 Sigma-70, non-essential region Retinal PF15449.1 KLO13363.1 - 0.12 10.0 4.7 0.12 10.0 3.2 1.0 1 0 0 1 1 1 0 Retinal protein Nop14 PF04147.7 KLO13363.1 - 0.16 9.8 10.4 0.14 10.0 7.2 1.0 1 0 0 1 1 1 0 Nop14-like family Nucleoplasmin PF03066.10 KLO13363.1 - 0.2 11.1 10.5 0.24 10.8 7.2 1.3 1 0 0 1 1 1 0 Nucleoplasmin Sigma70_ner PF04546.8 KLO13363.1 - 0.33 10.5 10.1 0.38 10.3 7.0 1.1 1 0 0 1 1 1 0 Sigma-70, non-essential region PBP1_TM PF14812.1 KLO13363.1 - 0.45 10.8 8.3 0.89 9.8 5.8 1.5 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal BTV_NS2 PF04514.7 KLO13363.1 - 0.59 8.9 3.2 0.61 8.9 2.2 1.1 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 TLP-20 PF06088.6 KLO13363.1 - 0.76 9.4 4.3 0.82 9.3 3.0 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) DUF1510 PF07423.6 KLO13363.1 - 0.8 9.0 6.9 0.82 8.9 4.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Phyto_Pns9_10 PF05878.6 KLO13363.1 - 0.92 8.4 3.8 0.99 8.3 2.6 1.1 1 0 0 1 1 1 0 Phytoreovirus nonstructural protein Pns9/Pns10 Sporozoite_P67 PF05642.6 KLO13363.1 - 1.1 7.0 6.2 1.1 7.0 4.3 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen SDA1 PF05285.7 KLO13363.1 - 1.9 7.6 10.4 2 7.6 7.2 1.1 1 0 0 1 1 1 0 SDA1 FAM176 PF14851.1 KLO13363.1 - 2.2 7.9 5.1 2.8 7.6 3.6 1.2 1 0 0 1 1 1 0 FAM176 family CDC45 PF02724.9 KLO13363.1 - 2.3 6.1 7.7 2.2 6.1 5.4 1.0 1 0 0 1 1 1 0 CDC45-like protein DUF2890 PF11081.3 KLO13363.1 - 2.4 8.1 7.7 2.9 7.9 5.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) Daxx PF03344.10 KLO13363.1 - 3.3 6.0 10.9 3.6 5.9 7.6 1.1 1 0 0 1 1 1 0 Daxx Family Pox_RNA_Pol_19 PF05320.7 KLO13363.1 - 3.6 7.2 6.3 5.4 6.7 4.4 1.3 1 0 0 1 1 1 0 Poxvirus DNA-directed RNA polymerase 19 kDa subunit NOA36 PF06524.7 KLO13363.1 - 3.8 6.6 9.2 4 6.6 6.4 1.1 1 0 0 1 1 1 0 NOA36 protein WW PF00397.21 KLO13366.1 - 0.0093 15.8 0.2 0.1 12.5 0.1 2.3 2 0 0 2 2 2 1 WW domain Tetraspannin PF00335.15 KLO13366.1 - 0.064 12.5 2.4 0.13 11.4 1.7 1.6 1 1 0 1 1 1 0 Tetraspanin family Fascin PF06268.8 KLO13368.1 - 0.003 17.6 0.0 0.011 15.7 0.0 1.8 2 0 0 2 2 2 1 Fascin domain DUF4098 PF13345.1 KLO13368.1 - 0.087 12.7 1.3 2.9 7.8 0.5 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4098) DUF4402 PF14352.1 KLO13368.1 - 0.94 9.9 3.8 1.7 9.0 0.9 2.2 2 1 1 3 3 3 0 Domain of unknown function (DUF4402) Piwi PF02171.12 KLO13369.1 - 1.2e-81 274.0 0.0 1.6e-81 273.6 0.0 1.1 1 0 0 1 1 1 1 Piwi domain PAZ PF02170.17 KLO13369.1 - 2.6e-18 65.6 0.0 5e-18 64.6 0.0 1.4 1 0 0 1 1 1 1 PAZ domain DUF1785 PF08699.5 KLO13369.1 - 1e-17 63.2 0.1 3.5e-17 61.4 0.1 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1785) MiaE PF06175.6 KLO13369.1 - 0.018 14.4 0.1 0.03 13.7 0.0 1.3 1 0 0 1 1 1 0 tRNA-(MS[2]IO[6]A)-hydroxylase (MiaE) p450 PF00067.17 KLO13370.1 - 1.3e-76 258.0 0.0 1.6e-76 257.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF981 PF06168.6 KLO13374.1 - 0.067 12.9 2.6 0.086 12.6 1.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF981) SH PF01445.12 KLO13374.1 - 0.14 11.7 0.3 0.14 11.7 0.2 2.4 2 1 0 2 2 2 0 Viral small hydrophobic protein ImpA-rel_N PF06812.7 KLO13374.1 - 1.2 9.0 3.9 7.8 6.3 0.1 2.5 2 0 0 2 2 2 0 ImpA-related N-terminal DUF3684 PF12449.3 KLO13376.1 - 0 1128.0 0.0 0 1127.6 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3684) HATPase_c_3 PF13589.1 KLO13376.1 - 0.0088 15.7 0.1 0.036 13.7 0.0 2.0 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 KLO13376.1 - 0.15 11.8 0.0 0.4 10.4 0.0 1.7 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF945 PF06097.6 KLO13376.1 - 0.21 10.3 0.0 0.37 9.4 0.0 1.3 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF945) p450 PF00067.17 KLO13377.1 - 1.3e-72 244.8 0.0 2.7e-72 243.7 0.0 1.4 1 1 0 1 1 1 1 Cytochrome P450 SICA_C PF12879.2 KLO13377.1 - 0.17 11.7 0.9 0.56 10.0 0.6 1.9 1 1 0 1 1 1 0 SICA C-terminal inner membrane domain Amidase PF01425.16 KLO13378.1 - 7.6e-77 259.0 0.0 5.2e-76 256.2 0.0 1.9 1 1 0 1 1 1 1 Amidase p450 PF00067.17 KLO13379.1 - 2.7e-72 243.7 0.1 5.6e-72 242.7 0.0 1.4 1 1 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 KLO13380.1 - 1e-74 251.7 0.1 2.5e-74 250.4 0.0 1.5 1 1 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 KLO13381.1 - 9.2e-72 242.0 0.0 2e-71 240.8 0.0 1.5 1 1 0 1 1 1 1 Cytochrome P450 Peptidase_C97 PF05903.9 KLO13382.1 - 1.4e-08 34.6 0.0 2.2e-08 34.0 0.0 1.3 1 0 0 1 1 1 1 PPPDE putative peptidase domain WPP PF13943.1 KLO13382.1 - 0.037 14.2 5.0 3.6 7.8 1.6 2.5 2 0 0 2 2 2 0 WPP domain LRAT PF04970.8 KLO13382.1 - 0.071 13.0 1.8 0.37 10.7 0.1 2.4 1 1 1 2 2 2 0 Lecithin retinol acyltransferase Cauli_VI PF01693.11 KLO13382.1 - 0.073 13.0 0.6 0.16 11.9 0.4 1.6 1 0 0 1 1 1 0 Caulimovirus viroplasmin DnaJ PF00226.26 KLO13383.1 - 2.8e-21 75.0 0.1 5.9e-21 73.9 0.1 1.6 1 0 0 1 1 1 1 DnaJ domain TGT PF01702.13 KLO13384.1 - 1.1e-20 73.9 0.0 8.7e-18 64.4 0.0 2.2 2 0 0 2 2 2 2 Queuine tRNA-ribosyltransferase Amidase PF01425.16 KLO13386.1 - 2e-72 244.4 0.0 1.1e-70 238.7 0.0 2.0 1 1 0 1 1 1 1 Amidase Abhydrolase_6 PF12697.2 KLO13387.1 - 9.1e-06 25.7 0.0 1.2e-05 25.2 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KLO13387.1 - 0.084 12.6 0.0 0.11 12.2 0.0 1.3 1 1 0 1 1 1 0 Alpha/beta hydrolase family Methyltransf_25 PF13649.1 KLO13389.1 - 9.7e-11 41.9 0.2 5.4e-10 39.5 0.2 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KLO13389.1 - 7.9e-05 22.2 0.0 0.00012 21.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KLO13389.1 - 0.00072 19.9 0.1 0.0042 17.5 0.0 2.3 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 KLO13389.1 - 0.0044 17.4 0.1 0.04 14.3 0.1 2.1 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.13 KLO13389.1 - 0.055 12.5 0.0 0.083 11.9 0.0 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_18 PF12847.2 KLO13389.1 - 0.11 13.0 0.0 0.23 12.0 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain DUF1890 PF09001.6 KLO13389.1 - 0.15 12.0 0.0 0.29 11.1 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1890) DUF2422 PF10337.4 KLO13390.1 - 1.1e-82 278.2 3.0 1.1e-82 278.2 2.1 2.7 3 0 0 3 3 3 1 Protein of unknown function (DUF2422) DUF2421 PF10334.4 KLO13390.1 - 7.5e-36 123.8 0.5 2.1e-34 119.1 0.2 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF2421) FUSC_2 PF13515.1 KLO13390.1 - 1.4e-07 31.4 17.0 1.4e-07 31.4 11.8 3.7 3 0 0 3 3 3 1 Fusaric acid resistance protein-like DUF2422 PF10337.4 KLO13391.1 - 6.2e-83 279.0 0.3 1.2e-82 278.1 0.2 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2422) DUF2421 PF10334.4 KLO13391.1 - 3.1e-29 102.2 0.4 2.8e-26 92.5 0.5 3.0 2 1 0 2 2 2 2 Protein of unknown function (DUF2421) FUSC_2 PF13515.1 KLO13391.1 - 5.5e-08 32.7 12.9 5.5e-08 32.7 8.9 3.0 3 0 0 3 3 3 1 Fusaric acid resistance protein-like WD40 PF00400.27 KLO13392.1 - 5e-20 70.5 5.9 1.9e-07 30.6 0.1 6.7 7 0 0 7 7 7 4 WD domain, G-beta repeat Nup160 PF11715.3 KLO13392.1 - 0.00034 18.9 0.2 0.0005 18.3 0.1 1.3 1 0 0 1 1 1 1 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 KLO13392.1 - 0.02 13.6 0.9 1.8 7.2 0.3 3.1 1 1 2 3 3 3 0 Nup133 N terminal like DUF3756 PF12581.3 KLO13392.1 - 0.032 13.8 0.1 0.11 12.1 0.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3756) Acetyltransf_7 PF13508.1 KLO13393.1 - 2.3e-06 27.6 0.0 5.4e-06 26.4 0.0 1.6 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 KLO13393.1 - 4.8e-06 26.5 0.0 8.9e-06 25.6 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 KLO13393.1 - 0.0025 17.9 0.0 0.0052 16.8 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain DUF3749 PF12568.3 KLO13393.1 - 0.09 12.3 0.0 0.18 11.3 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Mec-17 PF05301.6 KLO13393.1 - 0.15 12.0 0.0 0.27 11.1 0.0 1.4 1 0 0 1 1 1 0 Touch receptor neuron protein Mec-17 Acetyltransf_1 PF00583.19 KLO13394.1 - 2.3e-06 27.5 0.0 6.7e-06 26.0 0.0 1.9 2 1 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 KLO13394.1 - 0.00019 21.5 0.0 0.00032 20.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 KLO13394.1 - 0.0012 18.9 0.0 0.0054 16.8 0.0 2.0 1 1 1 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 KLO13394.1 - 0.016 15.0 0.0 0.042 13.7 0.0 1.7 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain PCDO_beta_N PF12391.3 KLO13394.1 - 0.044 13.2 0.8 0.11 12.0 0.5 1.6 1 0 0 1 1 1 0 Protocatechuate 3,4-dioxygenase beta subunit N terminal Hydrophobin PF01185.13 KLO13396.1 - 0.04 14.3 0.0 0.054 13.9 0.0 1.1 1 0 0 1 1 1 0 Fungal hydrophobin F-box PF00646.28 KLO13397.1 - 0.01 15.5 1.1 0.024 14.2 0.8 1.6 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 KLO13397.1 - 0.12 12.0 1.5 0.37 10.5 1.0 1.8 1 0 0 1 1 1 0 F-box-like Glyco_hydro_10 PF00331.15 KLO13398.1 - 1.4e-94 316.7 0.1 1.7e-94 316.4 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 Aldo_ket_red PF00248.16 KLO13400.1 - 9.6e-54 182.1 0.0 1.2e-53 181.7 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family DIOX_N PF14226.1 KLO13401.1 - 6.3e-26 91.1 0.0 1.2e-25 90.3 0.0 1.5 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 KLO13401.1 - 2.3e-20 72.7 0.0 3.5e-20 72.1 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily SKN1 PF03935.10 KLO13405.1 - 2.7e-192 639.4 2.2 3.3e-192 639.1 1.5 1.0 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) ABC_membrane PF00664.18 KLO13407.1 - 2e-51 175.0 32.2 9.2e-26 90.8 9.4 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 KLO13407.1 - 2.2e-51 173.7 0.0 2.5e-29 102.2 0.0 2.5 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 KLO13407.1 - 4e-10 40.1 0.0 0.0012 18.8 0.0 4.2 3 1 0 3 3 3 2 AAA domain SMC_N PF02463.14 KLO13407.1 - 6.4e-10 38.6 0.3 0.0022 17.2 0.0 4.0 3 1 1 4 4 4 3 RecF/RecN/SMC N terminal domain Miro PF08477.8 KLO13407.1 - 1.5e-07 31.9 0.2 0.0069 16.8 0.0 2.8 2 0 0 2 2 2 2 Miro-like protein MMR_HSR1 PF01926.18 KLO13407.1 - 1.7e-07 31.2 0.3 0.0055 16.6 0.0 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_29 PF13555.1 KLO13407.1 - 1.6e-06 27.5 0.1 0.028 13.9 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.1 KLO13407.1 - 1.7e-06 28.1 1.6 0.036 14.0 0.1 3.5 3 0 0 3 3 3 2 AAA ATPase domain AAA_25 PF13481.1 KLO13407.1 - 4e-06 26.3 0.3 0.0099 15.2 0.0 2.8 3 0 0 3 3 2 2 AAA domain AAA_22 PF13401.1 KLO13407.1 - 1.6e-05 25.0 0.1 0.066 13.3 0.0 2.9 2 1 0 2 2 2 2 AAA domain DUF258 PF03193.11 KLO13407.1 - 2.9e-05 23.3 0.5 0.14 11.3 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_23 PF13476.1 KLO13407.1 - 5e-05 23.7 3.7 0.097 12.9 0.0 3.6 3 1 0 3 3 2 1 AAA domain Dynamin_N PF00350.18 KLO13407.1 - 0.00037 20.3 3.9 0.09 12.5 0.1 2.9 3 0 0 3 3 3 2 Dynamin family AAA_17 PF13207.1 KLO13407.1 - 0.0004 21.1 0.0 1.4 9.7 0.0 2.8 2 0 0 2 2 2 2 AAA domain Zeta_toxin PF06414.7 KLO13407.1 - 0.0015 17.6 1.2 0.26 10.3 0.2 2.6 2 0 0 2 2 2 1 Zeta toxin FtsK_SpoIIIE PF01580.13 KLO13407.1 - 0.0019 17.6 0.1 0.81 9.1 0.0 2.4 2 0 0 2 2 2 1 FtsK/SpoIIIE family Arch_ATPase PF01637.13 KLO13407.1 - 0.0033 17.1 0.1 0.44 10.1 0.0 3.0 2 1 0 2 2 2 1 Archaeal ATPase MobB PF03205.9 KLO13407.1 - 0.0036 17.0 1.2 2.3 7.9 0.0 2.7 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B NACHT PF05729.7 KLO13407.1 - 0.006 16.2 1.8 0.55 9.8 0.0 2.5 2 0 0 2 2 2 1 NACHT domain AAA_18 PF13238.1 KLO13407.1 - 0.0082 16.4 1.2 5 7.4 0.0 3.0 3 0 0 3 3 2 0 AAA domain SbcCD_C PF13558.1 KLO13407.1 - 0.0088 15.9 0.2 0.41 10.5 0.1 2.9 2 1 0 2 2 2 1 Putative exonuclease SbcCD, C subunit UPF0079 PF02367.12 KLO13407.1 - 0.011 15.3 0.8 1.5 8.4 0.0 2.6 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 AAA_30 PF13604.1 KLO13407.1 - 0.012 15.1 0.5 2.4 7.6 0.0 2.9 3 0 0 3 3 3 0 AAA domain NB-ARC PF00931.17 KLO13407.1 - 0.013 14.4 0.4 4.2 6.1 0.0 2.4 2 0 0 2 2 2 0 NB-ARC domain ATP-synt_ab PF00006.20 KLO13407.1 - 0.013 14.9 0.1 3.7 6.9 0.0 2.3 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_10 PF12846.2 KLO13407.1 - 0.017 14.6 2.3 3.3 7.0 0.0 2.7 2 0 0 2 2 2 0 AAA-like domain DUF87 PF01935.12 KLO13407.1 - 0.022 14.5 2.3 0.64 9.7 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function DUF87 DUF815 PF05673.8 KLO13407.1 - 0.031 13.1 1.0 0.88 8.4 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF815) ArgK PF03308.11 KLO13407.1 - 0.031 13.0 1.2 1 8.1 0.1 2.3 2 0 0 2 2 2 0 ArgK protein PduV-EutP PF10662.4 KLO13407.1 - 0.034 13.6 1.0 7.9 5.9 0.1 2.7 3 0 0 3 3 2 0 Ethanolamine utilisation - propanediol utilisation TrwB_AAD_bind PF10412.4 KLO13407.1 - 0.039 12.5 0.2 5.8 5.4 0.0 2.4 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain cobW PF02492.14 KLO13407.1 - 0.11 11.8 2.3 5.2 6.4 0.1 2.5 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain RNA_helicase PF00910.17 KLO13407.1 - 0.15 12.2 0.0 17 5.6 0.0 2.8 2 0 0 2 2 2 0 RNA helicase AAA_15 PF13175.1 KLO13407.1 - 0.17 10.8 0.0 13 4.7 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain ABC_ATPase PF09818.4 KLO13407.1 - 0.36 9.3 1.3 76 1.6 0.0 3.6 4 0 0 4 4 4 0 Predicted ATPase of the ABC class COesterase PF00135.23 KLO13408.1 - 5.9e-158 526.9 0.0 4.9e-86 289.5 0.0 2.2 2 0 0 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.8 KLO13408.1 - 4.7e-09 36.1 4.5 0.00054 19.5 0.1 2.9 2 2 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KLO13408.1 - 2.8e-05 23.8 0.7 0.2 11.3 0.0 2.3 2 0 0 2 2 2 2 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 KLO13408.1 - 5.8e-05 22.4 0.0 0.16 11.1 0.0 2.3 2 0 0 2 2 2 2 Prolyl oligopeptidase family DUF2424 PF10340.4 KLO13408.1 - 0.011 14.3 0.0 1.4 7.5 0.0 3.4 4 0 0 4 4 4 0 Protein of unknown function (DUF2424) F-box-like PF12937.2 KLO13409.1 - 2.1e-08 33.7 3.8 8.2e-08 31.8 2.7 2.1 1 1 0 1 1 1 1 F-box-like F-box-like_2 PF13013.1 KLO13409.1 - 0.08 12.6 0.3 0.22 11.2 0.2 1.8 1 1 0 1 1 1 0 F-box-like domain F-box-like PF12937.2 KLO13410.1 - 6.1e-08 32.2 4.3 2.9e-07 30.0 2.9 2.3 1 1 0 1 1 1 1 F-box-like DUF2576 PF10845.3 KLO13410.1 - 0.09 11.9 0.0 0.18 10.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2576) COesterase PF00135.23 KLO13411.1 - 3.1e-86 290.2 0.1 4.7e-86 289.6 0.1 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 KLO13411.1 - 4.4e-05 23.1 1.1 0.00023 20.8 0.8 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold DUF2424 PF10340.4 KLO13411.1 - 0.062 11.9 0.0 0.46 9.0 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2424) Cellulase PF00150.13 KLO13412.1 - 0.0003 20.0 0.6 0.00065 18.9 0.4 1.6 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Chorion_3 PF05387.6 KLO13412.1 - 2.6 7.4 11.4 14 4.9 0.0 2.3 2 0 0 2 2 2 0 Chorion family 3 Secretin_N_2 PF07655.8 KLO13412.1 - 5.5 7.4 19.0 2.2e+02 2.3 12.8 2.9 2 0 0 2 2 2 0 Secretin N-terminal domain F-box-like PF12937.2 KLO13413.1 - 1.1e-05 25.0 1.5 3.2e-05 23.5 1.1 1.9 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.2 KLO13413.1 - 0.18 11.4 0.0 10 5.8 0.0 3.3 3 0 0 3 3 3 0 Leucine Rich repeats (2 copies) COesterase PF00135.23 KLO13414.1 - 2.5e-85 287.2 0.0 3e-85 286.9 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 KLO13414.1 - 3.6e-06 26.7 1.1 1.5e-05 24.6 0.8 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold TIM PF00121.13 KLO13415.1 - 2.4e-86 288.7 0.0 2.7e-86 288.6 0.0 1.0 1 0 0 1 1 1 1 Triosephosphate isomerase CutC PF03932.9 KLO13415.1 - 0.085 12.1 0.0 0.14 11.3 0.0 1.5 1 1 0 1 1 1 0 CutC family COesterase PF00135.23 KLO13416.1 - 5.4e-86 289.4 0.0 1.3e-85 288.1 0.0 1.6 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 KLO13416.1 - 0.0012 18.4 0.8 0.14 11.7 0.0 2.4 2 0 0 2 2 2 2 alpha/beta hydrolase fold RabGAP-TBC PF00566.13 KLO13417.1 - 1.9e-38 132.1 0.0 3.2e-38 131.3 0.0 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain RNase_H PF00075.19 KLO13418.1 - 4.5e-26 91.7 0.2 1.2e-25 90.3 0.0 1.8 2 0 0 2 2 2 1 RNase H Cauli_VI PF01693.11 KLO13418.1 - 1.5e-17 63.3 1.4 2.6e-17 62.5 1.0 1.4 1 0 0 1 1 1 1 Caulimovirus viroplasmin Glyco_hyd_65N_2 PF14498.1 KLO13419.1 - 0.0006 19.5 0.0 0.00086 19.0 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 65, N-terminal domain zf-MYND PF01753.13 KLO13420.1 - 3.6e-08 33.1 14.7 6e-08 32.4 10.2 1.4 1 0 0 1 1 1 1 MYND finger zf-Mss51 PF13824.1 KLO13420.1 - 0.041 13.7 5.7 0.089 12.6 4.0 1.5 1 0 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 Ecl1 PF12855.2 KLO13420.1 - 3.1 7.1 7.0 0.75 9.1 1.8 2.1 1 1 1 2 2 2 0 Life-span regulatory factor zf-MYND PF01753.13 KLO13421.1 - 6.9e-07 29.0 15.2 1.3e-06 28.1 10.5 1.5 1 0 0 1 1 1 1 MYND finger zf-Mss51 PF13824.1 KLO13421.1 - 0.87 9.4 6.5 1.9 8.3 4.5 1.5 1 0 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 APH PF01636.18 KLO13422.1 - 2.1e-21 76.7 0.1 5.7e-21 75.3 0.0 1.7 2 1 0 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 KLO13422.1 - 0.0021 17.6 0.0 0.012 15.1 0.0 2.1 3 0 0 3 3 3 1 Choline/ethanolamine kinase DUF1679 PF07914.6 KLO13422.1 - 0.18 10.3 0.0 1.4 7.4 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1679) Pro_isomerase PF00160.16 KLO13423.1 - 8.2e-45 152.7 0.0 9.2e-45 152.6 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Ras PF00071.17 KLO13424.1 - 1.3e-45 154.7 0.0 1.4e-45 154.5 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KLO13424.1 - 1.9e-19 70.3 0.0 2.5e-19 69.9 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KLO13424.1 - 2.3e-05 23.7 0.0 2.6e-05 23.5 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 KLO13424.1 - 0.00037 20.4 0.0 0.00047 20.1 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 KLO13424.1 - 0.0006 19.3 0.0 0.0026 17.2 0.0 1.9 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain Septin PF00735.13 KLO13424.1 - 0.014 14.4 0.0 2.6 6.9 0.0 2.2 2 0 0 2 2 2 0 Septin AAA_25 PF13481.1 KLO13424.1 - 0.017 14.5 0.4 0.15 11.4 0.2 2.1 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.1 KLO13424.1 - 0.053 13.5 0.0 0.59 10.0 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain p450 PF00067.17 KLO13425.1 - 1.6e-73 247.7 0.0 1.8e-73 247.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 KLO13426.1 - 6.3e-64 216.1 0.0 7.8e-64 215.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 KLO13427.1 - 9.6e-65 218.8 0.0 1.2e-64 218.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Zn_clus PF00172.13 KLO13428.1 - 0.0064 16.3 13.5 0.011 15.6 9.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain p450 PF00067.17 KLO13429.1 - 7.8e-70 235.6 0.0 9.6e-70 235.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 KLO13430.1 - 2.1e-68 230.9 0.0 2.6e-68 230.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 KLO13431.1 - 1.1e-64 218.7 0.0 5.2e-50 170.3 0.0 2.1 2 0 0 2 2 2 2 Cytochrome P450 NicO PF03824.11 KLO13431.1 - 0.17 11.2 0.0 0.45 9.7 0.0 1.6 2 0 0 2 2 2 0 High-affinity nickel-transport protein p450 PF00067.17 KLO13432.1 - 4.7e-69 233.0 0.0 6e-69 232.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 GPP34 PF05719.6 KLO13433.1 - 1.2e-58 198.5 0.6 1.6e-58 198.2 0.4 1.1 1 0 0 1 1 1 1 Golgi phosphoprotein 3 (GPP34) Apolipoprotein PF01442.13 KLO13435.1 - 3.4e-05 23.4 0.7 0.0001 21.9 0.2 1.9 1 1 0 1 1 1 1 Apolipoprotein A1/A4/E domain MCPsignal PF00015.16 KLO13435.1 - 5.5e-05 22.8 8.0 0.0024 17.4 0.2 3.0 1 1 1 2 2 2 2 Methyl-accepting chemotaxis protein (MCP) signalling domain Spc7 PF08317.6 KLO13435.1 - 0.00022 20.0 1.2 0.00022 20.0 0.8 2.7 1 1 2 3 3 3 1 Spc7 kinetochore protein DUF1664 PF07889.7 KLO13435.1 - 0.00029 20.6 8.5 0.11 12.3 0.1 3.4 3 0 0 3 3 3 2 Protein of unknown function (DUF1664) DUF4559 PF15112.1 KLO13435.1 - 0.00048 19.3 7.4 0.0017 17.5 0.5 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF4559) DUF2205 PF10224.4 KLO13435.1 - 0.019 14.5 3.3 2.3 7.8 0.1 3.3 2 1 0 2 2 2 0 Predicted coiled-coil protein (DUF2205) NPV_P10 PF05531.7 KLO13435.1 - 0.024 14.8 1.6 2.5 8.4 0.0 3.5 3 0 0 3 3 3 0 Nucleopolyhedrovirus P10 protein Uds1 PF15456.1 KLO13435.1 - 0.044 13.7 0.4 0.044 13.7 0.3 3.2 3 1 0 3 3 3 0 Up-regulated During Septation PilJ PF13675.1 KLO13435.1 - 0.078 13.2 3.5 7.6 6.9 0.3 3.6 3 0 0 3 3 3 0 Type IV pili methyl-accepting chemotaxis transducer N-term Reo_sigmaC PF04582.7 KLO13435.1 - 0.26 10.4 3.4 9.1 5.3 0.2 2.4 1 1 2 3 3 3 0 Reovirus sigma C capsid protein GATase_2 PF00310.16 KLO13435.1 - 0.29 9.8 2.8 0.62 8.7 0.9 2.2 2 1 0 2 2 2 0 Glutamine amidotransferases class-II IZUMO PF15005.1 KLO13435.1 - 0.32 11.0 3.1 1.4 8.9 0.0 2.7 2 1 0 3 3 3 0 Izumo sperm-egg fusion YPEB PF14620.1 KLO13435.1 - 0.36 9.8 5.9 1.3 7.9 1.4 2.4 2 1 0 2 2 2 0 YpeB sporulation IncA PF04156.9 KLO13435.1 - 0.62 9.6 14.4 0.57 9.7 0.4 3.2 3 0 0 3 3 3 0 IncA protein COG5 PF10392.4 KLO13435.1 - 1.1 9.1 7.1 7.7 6.4 0.2 3.3 3 1 0 3 3 3 0 Golgi transport complex subunit 5 Seryl_tRNA_N PF02403.17 KLO13435.1 - 1.5 8.8 13.7 0.45 10.5 0.2 3.8 3 1 0 3 3 3 0 Seryl-tRNA synthetase N-terminal domain SPX PF03105.14 KLO13435.1 - 1.9 8.2 6.3 3.1 7.4 4.3 1.6 1 1 0 1 1 1 0 SPX domain Syntaxin-6_N PF09177.6 KLO13435.1 - 4.2 7.8 9.2 12 6.3 0.1 4.0 2 1 1 3 3 3 0 Syntaxin 6, N-terminal Laminin_II PF06009.7 KLO13435.1 - 7.2 6.3 9.2 2 8.1 0.1 3.0 3 0 0 3 3 3 0 Laminin Domain II FH2 PF02181.18 KLO13436.1 - 0.016 14.0 1.5 0.023 13.5 1.0 1.2 1 0 0 1 1 1 0 Formin Homology 2 Domain DUF2763 PF10961.3 KLO13436.1 - 0.066 13.6 0.0 0.22 11.9 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2763) TMEM219 PF14940.1 KLO13436.1 - 0.083 11.9 0.0 0.13 11.3 0.0 1.2 1 0 0 1 1 1 0 Transmembrane 219 Vps54 PF07928.7 KLO13436.1 - 0.19 11.8 1.2 1.5 8.9 0.1 2.3 2 0 0 2 2 2 0 Vps54-like protein Hormone_1 PF00103.15 KLO13436.1 - 0.57 9.4 2.8 6.2 6.1 0.1 2.2 2 0 0 2 2 2 0 Somatotropin hormone family Apolipoprotein PF01442.13 KLO13437.1 - 0.00088 18.8 4.4 0.0053 16.3 2.7 2.4 1 1 0 1 1 1 1 Apolipoprotein A1/A4/E domain Reo_sigmaC PF04582.7 KLO13437.1 - 0.0019 17.4 2.8 0.0096 15.1 0.1 2.4 2 1 0 2 2 2 1 Reovirus sigma C capsid protein PLC-beta_C PF08703.5 KLO13437.1 - 0.0034 17.1 5.3 0.0063 16.2 3.7 1.4 1 0 0 1 1 1 1 PLC-beta C terminal Baculo_PEP_C PF04513.7 KLO13437.1 - 0.0038 17.0 4.1 0.29 10.9 0.0 3.7 3 1 0 3 3 3 1 Baculovirus polyhedron envelope protein, PEP, C terminus Fib_alpha PF08702.5 KLO13437.1 - 0.0038 17.3 9.4 0.0054 16.8 3.6 3.0 2 1 1 3 3 3 1 Fibrinogen alpha/beta chain family Surfac_D-trimer PF09006.6 KLO13437.1 - 0.0046 16.6 1.2 0.19 11.4 0.1 2.5 2 0 0 2 2 2 1 Lung surfactant protein D coiled-coil trimerisation DUF2408 PF10303.4 KLO13437.1 - 0.0048 17.0 5.9 0.0051 16.9 1.1 2.5 2 1 0 2 2 2 1 Protein of unknown function (DUF2408) Exonuc_VII_S PF02609.11 KLO13437.1 - 0.0049 16.6 2.3 1.8 8.3 0.1 3.2 4 0 0 4 4 3 1 Exonuclease VII small subunit Vps5 PF09325.5 KLO13437.1 - 0.0055 15.9 5.9 0.54 9.4 1.4 3.4 2 1 1 3 3 3 1 Vps5 C terminal like MscS_porin PF12795.2 KLO13437.1 - 0.014 14.6 1.6 0.065 12.5 1.0 2.0 1 1 0 1 1 1 0 Mechanosensitive ion channel porin domain DUF4071 PF13281.1 KLO13437.1 - 0.014 14.2 1.1 0.016 14.0 0.1 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4071) Exonuc_VII_L PF02601.10 KLO13437.1 - 0.015 14.5 2.5 0.027 13.6 1.8 1.4 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF1664 PF07889.7 KLO13437.1 - 0.021 14.6 0.7 0.021 14.6 0.5 3.1 2 1 0 3 3 3 0 Protein of unknown function (DUF1664) IncA PF04156.9 KLO13437.1 - 0.021 14.4 1.3 0.021 14.4 0.9 2.8 2 1 2 4 4 3 0 IncA protein HemX PF04375.9 KLO13437.1 - 0.025 13.2 1.3 0.05 12.1 0.9 1.6 1 0 0 1 1 1 0 HemX DUF883 PF05957.8 KLO13437.1 - 0.025 14.9 5.0 3 8.3 2.3 2.9 1 1 2 3 3 2 0 Bacterial protein of unknown function (DUF883) CENP-Q PF13094.1 KLO13437.1 - 0.025 14.6 2.9 0.38 10.7 0.2 2.5 2 0 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit SlyX PF04102.7 KLO13437.1 - 0.035 14.4 0.4 0.035 14.4 0.3 2.9 3 1 0 3 3 2 0 SlyX YPEB PF14620.1 KLO13437.1 - 0.039 12.9 4.1 0.026 13.5 1.7 1.5 2 0 0 2 2 1 0 YpeB sporulation DUF241 PF03087.9 KLO13437.1 - 0.053 13.0 6.1 0.041 13.3 3.1 1.8 2 0 0 2 2 1 0 Arabidopsis protein of unknown function TMP_2 PF06791.8 KLO13437.1 - 0.053 13.1 0.1 0.14 11.7 0.1 1.7 1 0 0 1 1 1 0 Prophage tail length tape measure protein MCPsignal PF00015.16 KLO13437.1 - 0.084 12.4 10.3 0.047 13.2 5.2 2.0 2 1 0 2 2 1 0 Methyl-accepting chemotaxis protein (MCP) signalling domain Mnd1 PF03962.10 KLO13437.1 - 0.084 12.5 12.9 0.049 13.3 6.3 2.6 3 1 0 3 3 1 0 Mnd1 family ISG65-75 PF11727.3 KLO13437.1 - 0.09 11.8 6.0 0.17 10.8 4.2 1.5 1 0 0 1 1 1 0 Invariant surface glycoprotein Vps51 PF08700.6 KLO13437.1 - 0.095 12.5 5.7 1.9 8.3 0.2 4.1 3 1 1 4 4 4 0 Vps51/Vps67 DUF148 PF02520.12 KLO13437.1 - 0.12 12.1 0.2 0.12 12.1 0.1 2.7 2 1 0 3 3 2 0 Domain of unknown function DUF148 SPX PF03105.14 KLO13437.1 - 0.12 12.1 4.4 0.19 11.4 3.1 1.3 1 0 0 1 1 1 0 SPX domain DUF651 PF04895.7 KLO13437.1 - 0.13 11.8 2.2 3 7.5 0.0 3.8 3 1 2 5 5 5 0 Archaeal protein of unknown function (DUF651) Spc7 PF08317.6 KLO13437.1 - 0.17 10.5 9.6 0.28 9.7 5.5 2.1 2 1 0 2 2 2 0 Spc7 kinetochore protein HSA PF07529.8 KLO13437.1 - 0.22 11.3 4.7 0.55 10.0 3.2 1.6 1 0 0 1 1 1 0 HSA DUF948 PF06103.6 KLO13437.1 - 0.22 11.4 8.0 1.7 8.5 0.2 3.8 3 1 0 3 3 3 0 Bacterial protein of unknown function (DUF948) P4Ha_N PF08336.6 KLO13437.1 - 0.23 11.2 2.6 0.77 9.5 1.1 2.4 1 1 1 2 2 2 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region CorA PF01544.13 KLO13437.1 - 0.25 10.3 2.4 0.86 8.5 0.6 2.3 1 1 1 2 2 2 0 CorA-like Mg2+ transporter protein NPV_P10 PF05531.7 KLO13437.1 - 0.29 11.4 8.6 0.73 10.1 0.1 4.4 3 2 1 4 4 4 0 Nucleopolyhedrovirus P10 protein Prefoldin_2 PF01920.15 KLO13437.1 - 0.33 10.7 11.7 0.31 10.8 0.9 4.4 4 1 0 4 4 4 0 Prefoldin subunit TPR_MLP1_2 PF07926.7 KLO13437.1 - 0.37 10.5 10.2 0.23 11.1 3.3 3.0 3 1 0 3 3 2 0 TPR/MLP1/MLP2-like protein RP-C_C PF11800.3 KLO13437.1 - 0.48 10.0 5.0 0.66 9.6 2.9 1.6 2 0 0 2 2 1 0 Replication protein C C-terminal region TBPIP PF07106.8 KLO13437.1 - 0.53 9.8 11.9 1.4 8.4 0.4 3.7 2 1 2 4 4 4 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) PSII_Pbs27 PF13326.1 KLO13437.1 - 0.56 10.1 3.2 1.2 9.1 0.1 2.7 3 0 0 3 3 3 0 Photosystem II Pbs27 FH2 PF02181.18 KLO13437.1 - 0.61 8.9 10.2 4.3 6.1 0.0 2.7 3 1 0 3 3 2 0 Formin Homology 2 Domain DUF4446 PF14584.1 KLO13437.1 - 0.62 9.8 3.9 0.91 9.3 0.2 2.8 1 1 2 3 3 3 0 Protein of unknown function (DUF4446) Prominin PF05478.6 KLO13437.1 - 0.73 7.2 3.6 0.47 7.9 0.6 1.7 1 1 0 1 1 1 0 Prominin Syntaxin_2 PF14523.1 KLO13437.1 - 0.97 9.5 8.1 2.1 8.4 2.4 3.0 3 1 0 3 3 2 0 Syntaxin-like protein DUF2959 PF11172.3 KLO13437.1 - 1 9.0 7.0 3.3 7.4 3.4 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF2959) FliJ PF02050.11 KLO13437.1 - 1.1 9.3 10.4 2.4 8.2 0.2 3.8 3 1 1 4 4 4 0 Flagellar FliJ protein FlaC_arch PF05377.6 KLO13437.1 - 1.2 9.1 8.6 2.8 7.9 0.1 4.0 4 0 0 4 4 3 0 Flagella accessory protein C (FlaC) DUF4200 PF13863.1 KLO13437.1 - 1.5 8.7 13.9 8.1 6.4 7.2 3.2 2 1 1 3 3 3 0 Domain of unknown function (DUF4200) BLOC1_2 PF10046.4 KLO13437.1 - 1.8 8.7 10.8 7.7 6.7 0.1 4.1 4 1 1 5 5 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Syntaxin-6_N PF09177.6 KLO13437.1 - 1.9 8.9 9.7 0.8 10.1 0.6 3.5 2 1 0 3 3 3 0 Syntaxin 6, N-terminal AATF-Che1 PF13339.1 KLO13437.1 - 2.2 8.4 8.3 7.2 6.7 3.6 2.7 1 1 1 2 2 2 0 Apoptosis antagonizing transcription factor Syntaxin PF00804.20 KLO13437.1 - 4.7 7.4 11.6 0.61 10.2 1.9 3.1 2 1 1 3 3 2 0 Syntaxin Laminin_II PF06009.7 KLO13437.1 - 5.3 6.8 12.4 0.53 10.0 0.4 3.5 2 1 2 4 4 3 0 Laminin Domain II APG6 PF04111.7 KLO13437.1 - 6.2 5.7 9.9 20 4.0 6.8 1.9 1 1 0 1 1 1 0 Autophagy protein Apg6 DUF16 PF01519.11 KLO13437.1 - 7 6.9 9.1 11 6.3 5.2 2.1 1 1 1 2 2 2 0 Protein of unknown function DUF16 DUF972 PF06156.8 KLO13437.1 - 8.1 6.8 10.2 9.1 6.6 4.4 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF972) TMPIT PF07851.8 KLO13437.1 - 8.9 5.2 8.2 3.6 6.5 1.2 2.2 2 1 1 3 3 2 0 TMPIT-like protein Sigma70_r3 PF04539.11 KLO13439.1 - 0.0072 16.1 0.1 0.02 14.7 0.1 1.7 1 0 0 1 1 1 1 Sigma-70 region 3 Fungal_trans_2 PF11951.3 KLO13439.1 - 0.033 12.8 0.1 0.057 12.0 0.0 1.3 1 0 0 1 1 1 0 Fungal specific transcription factor domain SF-assemblin PF06705.6 KLO13439.1 - 0.067 12.3 0.6 0.13 11.3 0.3 1.5 1 1 0 1 1 1 0 SF-assemblin/beta giardin Laminin_II PF06009.7 KLO13439.1 - 0.071 12.8 2.2 0.13 12.0 0.3 2.3 3 0 0 3 3 3 0 Laminin Domain II CENP-Q PF13094.1 KLO13439.1 - 0.58 10.1 2.9 39 4.2 0.0 3.1 2 1 1 3 3 3 0 CENP-Q, a CENPA-CAD centromere complex subunit VirD1 PF07328.6 KLO13440.1 - 0.096 12.4 0.0 0.11 12.2 0.0 1.0 1 0 0 1 1 1 0 T-DNA border endonuclease VirD1 DUF3086 PF11285.3 KLO13441.1 - 0.014 14.2 0.1 0.065 12.0 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3086) Apolipoprotein PF01442.13 KLO13441.1 - 0.049 13.1 0.1 0.25 10.8 0.0 2.0 2 1 0 2 2 2 0 Apolipoprotein A1/A4/E domain DNA_repr_REX1B PF14966.1 KLO13441.1 - 0.052 13.9 0.1 2.5 8.5 0.0 2.3 2 0 0 2 2 2 0 DNA repair REX1-B Mating_N PF12731.2 KLO13441.1 - 0.054 13.3 1.0 0.68 9.8 0.0 2.5 3 0 0 3 3 3 0 Mating-type protein beta 1 Vps5 PF09325.5 KLO13441.1 - 0.056 12.6 0.5 3.9 6.6 0.0 2.2 2 0 0 2 2 2 0 Vps5 C terminal like Syntaxin_2 PF14523.1 KLO13441.1 - 0.088 12.8 0.1 1.6 8.8 0.0 2.4 2 0 0 2 2 2 0 Syntaxin-like protein DUF1664 PF07889.7 KLO13441.1 - 0.12 12.2 0.2 5.1 6.9 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) DUF1104 PF06518.6 KLO13442.1 - 0.066 13.3 0.0 3.4 7.8 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1104) DUF1129 PF06570.6 KLO13443.1 - 0.0075 15.5 0.3 0.71 9.1 0.1 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF1129) DUF872 PF05915.7 KLO13443.1 - 0.048 13.5 0.2 0.32 10.8 0.1 2.1 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF872) DUF4064 PF13273.1 KLO13443.1 - 0.076 13.1 3.2 4.6 7.3 0.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF4064) DUF3995 PF13160.1 KLO13443.1 - 0.57 10.2 4.8 0.14 12.2 0.5 2.0 2 1 0 2 2 2 0 Protein of unknown function (DUF3995) DUF4131 PF13567.1 KLO13443.1 - 4.2 6.7 5.3 35 3.7 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) Flavi_NS1 PF00948.16 KLO13444.1 - 0.011 14.1 0.0 1.5 7.1 0.0 2.1 2 0 0 2 2 2 0 Flavivirus non-structural Protein NS1 NAAA-beta PF15508.1 KLO13444.1 - 0.079 13.3 0.0 0.27 11.5 0.0 1.9 2 0 0 2 2 2 0 beta subunit of N-acylethanolamine-hydrolyzing acid amidase Baculo_PEP_C PF04513.7 KLO13444.1 - 0.11 12.3 0.5 22 4.8 0.0 2.5 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Catalase-rel PF06628.7 KLO13444.1 - 0.11 12.3 0.0 0.52 10.2 0.0 2.0 2 0 0 2 2 2 0 Catalase-related immune-responsive Mnd1 PF03962.10 KLO13445.1 - 0.16 11.5 6.7 0.15 11.6 3.0 2.0 1 1 1 2 2 2 0 Mnd1 family DUF724 PF05266.9 KLO13445.1 - 0.8 9.3 7.0 0.033 13.8 0.7 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF724) Cu-oxidase_2 PF07731.9 KLO13449.1 - 0.08 12.4 0.0 0.092 12.2 0.0 1.2 1 0 0 1 1 1 0 Multicopper oxidase Prominin PF05478.6 KLO13450.1 - 0.001 16.7 1.0 0.0013 16.4 0.7 1.1 1 0 0 1 1 1 1 Prominin RmuC PF02646.11 KLO13450.1 - 0.002 17.0 2.8 0.0046 15.8 1.7 1.8 1 1 0 1 1 1 1 RmuC family DUF793 PF05633.6 KLO13450.1 - 0.002 16.9 2.4 0.071 11.8 0.6 2.1 1 1 1 2 2 2 1 Protein of unknown function (DUF793) Reo_sigmaC PF04582.7 KLO13450.1 - 0.0022 17.2 0.1 0.0038 16.4 0.1 1.3 1 0 0 1 1 1 1 Reovirus sigma C capsid protein Mnd1 PF03962.10 KLO13450.1 - 0.01 15.4 3.3 0.01 15.4 2.3 2.1 1 1 1 2 2 2 0 Mnd1 family DUF1664 PF07889.7 KLO13450.1 - 0.012 15.4 0.1 0.036 13.8 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Syntaxin_2 PF14523.1 KLO13450.1 - 0.018 15.0 6.1 0.04 13.9 3.4 2.1 2 0 0 2 2 2 0 Syntaxin-like protein DUF3829 PF12889.2 KLO13450.1 - 0.02 14.0 0.3 0.045 12.9 0.1 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3829) SPX PF03105.14 KLO13450.1 - 0.028 14.1 3.0 0.039 13.7 2.1 1.2 1 0 0 1 1 1 0 SPX domain Syntaxin-6_N PF09177.6 KLO13450.1 - 0.031 14.6 4.0 0.34 11.3 1.7 3.0 1 1 3 4 4 4 0 Syntaxin 6, N-terminal DegQ PF08181.6 KLO13450.1 - 0.047 13.4 0.3 0.17 11.6 0.0 2.1 2 0 0 2 2 1 0 DegQ (SacQ) family Spc7 PF08317.6 KLO13450.1 - 0.058 12.0 5.2 0.087 11.4 3.6 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein Baculo_PEP_C PF04513.7 KLO13450.1 - 0.062 13.1 0.0 0.15 11.8 0.0 1.8 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Fzo_mitofusin PF04799.8 KLO13450.1 - 0.072 12.4 1.6 0.35 10.2 0.1 2.6 1 1 1 3 3 3 0 fzo-like conserved region ArgK PF03308.11 KLO13450.1 - 0.084 11.6 1.7 0.15 10.8 1.2 1.4 1 0 0 1 1 1 0 ArgK protein APG6 PF04111.7 KLO13450.1 - 0.084 11.8 5.8 0.14 11.1 4.1 1.4 1 0 0 1 1 1 0 Autophagy protein Apg6 Fib_alpha PF08702.5 KLO13450.1 - 0.19 11.8 3.3 0.31 11.1 0.0 2.1 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Ax_dynein_light PF10211.4 KLO13450.1 - 0.21 11.4 7.9 0.33 10.7 5.0 1.7 1 1 1 2 2 2 0 Axonemal dynein light chain Laminin_II PF06009.7 KLO13450.1 - 0.22 11.2 3.3 2.1 8.0 0.1 2.2 1 1 1 2 2 2 0 Laminin Domain II CENP-Q PF13094.1 KLO13450.1 - 0.28 11.2 8.2 0.81 9.6 5.5 1.9 1 1 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit DUF972 PF06156.8 KLO13450.1 - 0.37 11.1 7.0 0.69 10.2 2.6 2.5 1 1 2 3 3 3 0 Protein of unknown function (DUF972) IncA PF04156.9 KLO13450.1 - 1.9 8.0 13.2 0.92 9.0 7.3 1.8 2 1 0 2 2 1 0 IncA protein V_ATPase_I PF01496.14 KLO13450.1 - 3.1 5.5 7.7 5.6 4.6 5.1 1.4 1 1 1 2 2 2 0 V-type ATPase 116kDa subunit family DUF4140 PF13600.1 KLO13450.1 - 9.3 6.7 9.3 1.2 9.5 0.1 3.0 2 1 1 3 3 3 0 N-terminal domain of unknown function (DUF4140) Lzipper-MIP1 PF14389.1 KLO13452.1 - 0.054 13.6 0.7 2 8.5 0.0 3.0 3 0 0 3 3 3 0 Leucine-zipper of ternary complex factor MIP1 NPV_P10 PF05531.7 KLO13452.1 - 0.076 13.2 1.6 8.1 6.7 0.1 3.6 3 0 0 3 3 3 0 Nucleopolyhedrovirus P10 protein TBPIP PF07106.8 KLO13452.1 - 0.22 11.0 7.8 2.3 7.7 2.3 3.4 2 1 1 3 3 3 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) RBD-FIP PF09457.5 KLO13452.1 - 0.33 10.7 4.9 1.5 8.6 0.1 2.9 3 0 0 3 3 3 0 FIP domain Ax_dynein_light PF10211.4 KLO13452.1 - 0.44 10.3 4.5 1.9 8.2 0.2 2.3 2 0 0 2 2 2 0 Axonemal dynein light chain Syntaxin-6_N PF09177.6 KLO13452.1 - 5.1 7.5 6.7 36 4.8 0.1 4.0 5 0 0 5 5 5 0 Syntaxin 6, N-terminal FlaF PF07309.6 KLO13454.1 - 0.041 13.7 3.4 3 7.7 0.2 3.2 2 2 2 4 4 4 0 Flagellar protein FlaF Rsd_AlgQ PF04353.8 KLO13455.1 - 0.0086 15.7 1.5 0.016 14.9 0.3 2.0 1 1 1 2 2 2 1 Regulator of RNA polymerase sigma(70) subunit, Rsd/AlgQ Mnd1 PF03962.10 KLO13455.1 - 0.029 14.0 9.9 0.029 14.0 5.8 1.7 1 1 0 1 1 1 0 Mnd1 family DegQ PF08181.6 KLO13455.1 - 0.056 13.1 1.6 0.082 12.6 0.1 2.1 2 0 0 2 2 2 0 DegQ (SacQ) family CENP-Q PF13094.1 KLO13455.1 - 0.27 11.2 8.3 0.64 10.0 5.7 1.9 1 1 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit DUF342 PF03961.8 KLO13455.1 - 1.7 6.9 8.5 1.2 7.5 3.8 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF342) TMF_TATA_bd PF12325.3 KLO13455.1 - 1.9 8.2 9.7 0.35 10.5 4.0 1.8 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding MerR-DNA-bind PF09278.6 KLO13455.1 - 3.2 8.2 6.9 9.4 6.7 0.1 3.3 3 0 0 3 3 3 0 MerR, DNA binding DUF1664 PF07889.7 KLO13456.1 - 0.0038 17.0 6.5 0.57 9.9 0.1 4.0 2 1 2 4 4 4 1 Protein of unknown function (DUF1664) COG2 PF06148.6 KLO13456.1 - 0.0071 16.2 5.4 0.4 10.5 1.6 3.2 2 1 0 2 2 2 1 COG (conserved oligomeric Golgi) complex component, COG2 Reo_sigmaC PF04582.7 KLO13456.1 - 0.0075 15.4 1.5 0.95 8.5 0.1 2.1 2 0 0 2 2 2 2 Reovirus sigma C capsid protein FlaC_arch PF05377.6 KLO13456.1 - 0.012 15.5 1.8 5.7 6.9 0.0 3.6 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) IncA PF04156.9 KLO13456.1 - 0.099 12.2 2.9 6.4 6.3 1.0 2.5 1 1 1 2 2 2 0 IncA protein TMF_TATA_bd PF12325.3 KLO13456.1 - 0.36 10.5 3.9 0.52 10.0 0.4 2.7 3 1 0 3 3 3 0 TATA element modulatory factor 1 TATA binding YlqD PF11068.3 KLO13456.1 - 0.56 10.2 6.0 0.074 13.0 0.4 2.1 2 1 1 3 3 3 0 YlqD protein Seryl_tRNA_N PF02403.17 KLO13456.1 - 8.4 6.4 13.3 87 3.1 0.3 3.3 1 1 1 3 3 3 0 Seryl-tRNA synthetase N-terminal domain Phytoreo_Pns PF05451.6 KLO13459.1 - 0.0018 17.0 0.0 0.0024 16.5 0.0 1.1 1 0 0 1 1 1 1 Phytoreovirus nonstructural protein Pns10/11 DUF2281 PF10047.4 KLO13460.1 - 0.015 15.5 0.1 0.047 13.9 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2281) Exonuc_V_gamma PF04257.9 KLO13460.1 - 0.038 11.9 0.1 0.047 11.6 0.1 1.1 1 0 0 1 1 1 0 Exodeoxyribonuclease V, gamma subunit SPX PF03105.14 KLO13461.1 - 0.00012 21.9 2.7 0.00016 21.5 1.9 1.2 1 0 0 1 1 1 1 SPX domain DUF342 PF03961.8 KLO13461.1 - 0.00013 20.5 3.1 0.00019 19.9 2.2 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF342) Mnd1 PF03962.10 KLO13461.1 - 0.0014 18.3 6.0 0.0015 18.2 3.4 1.6 2 0 0 2 2 1 1 Mnd1 family Ax_dynein_light PF10211.4 KLO13461.1 - 0.0015 18.3 7.0 0.003 17.4 4.9 1.5 1 0 0 1 1 1 1 Axonemal dynein light chain Transposase_22 PF02994.9 KLO13461.1 - 0.0023 16.4 3.4 0.0031 16.0 2.3 1.3 1 1 0 1 1 1 1 L1 transposable element Packaging_FI PF14000.1 KLO13461.1 - 0.0037 17.4 3.7 0.0082 16.3 2.6 1.5 1 0 0 1 1 1 1 DNA packaging protein FI YlqD PF11068.3 KLO13461.1 - 0.0049 16.8 5.8 0.033 14.2 4.0 2.2 2 0 0 2 2 2 1 YlqD protein Atg14 PF10186.4 KLO13461.1 - 0.008 15.1 7.0 0.011 14.6 4.9 1.3 1 0 0 1 1 1 1 UV radiation resistance protein and autophagy-related subunit 14 Glyco_hydro_4C PF11975.3 KLO13461.1 - 0.0086 15.8 1.3 0.015 15.0 0.9 1.4 1 0 0 1 1 1 1 Family 4 glycosyl hydrolase C-terminal domain APG6 PF04111.7 KLO13461.1 - 0.027 13.5 4.4 0.043 12.8 3.0 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 Fzo_mitofusin PF04799.8 KLO13461.1 - 0.04 13.3 1.4 0.089 12.1 0.9 1.6 1 0 0 1 1 1 0 fzo-like conserved region DUF1192 PF06698.6 KLO13461.1 - 0.054 13.3 2.0 0.18 11.6 1.4 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF1192) DUF3573 PF12097.3 KLO13461.1 - 0.058 11.9 2.2 0.079 11.5 1.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) DUF972 PF06156.8 KLO13461.1 - 0.1 12.9 7.9 0.28 11.5 5.2 1.9 2 0 0 2 2 1 0 Protein of unknown function (DUF972) V_ATPase_I PF01496.14 KLO13461.1 - 0.11 10.3 2.7 0.15 9.8 1.9 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF1664 PF07889.7 KLO13461.1 - 0.23 11.2 5.3 0.37 10.5 2.1 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) DUF2312 PF10073.4 KLO13461.1 - 0.25 10.7 5.7 0.19 11.1 1.6 2.6 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2312) Syntaxin-6_N PF09177.6 KLO13461.1 - 0.37 11.2 5.3 0.27 11.6 1.2 2.7 3 1 0 3 3 2 0 Syntaxin 6, N-terminal IncA PF04156.9 KLO13461.1 - 0.51 9.9 10.7 0.069 12.7 3.0 2.4 3 0 0 3 3 2 0 IncA protein Seryl_tRNA_N PF02403.17 KLO13461.1 - 0.53 10.3 9.8 2.4 8.2 5.7 2.7 3 0 0 3 3 2 0 Seryl-tRNA synthetase N-terminal domain RmuC PF02646.11 KLO13461.1 - 0.54 9.0 8.0 0.82 8.4 4.4 2.0 1 1 1 2 2 2 0 RmuC family MCPsignal PF00015.16 KLO13461.1 - 0.75 9.3 11.9 0.34 10.4 5.0 2.4 2 1 0 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain Hormone_1 PF00103.15 KLO13461.1 - 1.6 8.0 6.6 0.93 8.7 2.3 2.1 1 1 1 2 2 2 0 Somatotropin hormone family FlaC_arch PF05377.6 KLO13461.1 - 1.7 8.6 4.6 1 9.3 1.2 2.1 2 0 0 2 2 1 0 Flagella accessory protein C (FlaC) DUF2203 PF09969.4 KLO13461.1 - 1.8 8.8 5.4 1.8 8.8 2.3 2.0 2 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) Apt1 PF10351.4 KLO13461.1 - 2 7.2 9.6 0.35 9.6 4.0 1.5 2 0 0 2 2 2 0 Golgi-body localisation protein domain COG2 PF06148.6 KLO13461.1 - 2.2 8.1 6.6 0.88 9.4 1.6 2.6 3 0 0 3 3 2 0 COG (conserved oligomeric Golgi) complex component, COG2 MerR-DNA-bind PF09278.6 KLO13461.1 - 2.7 8.4 6.0 1.7 9.1 0.9 3.1 3 1 0 3 3 2 0 MerR, DNA binding HalX PF08663.5 KLO13461.1 - 3 7.8 7.1 11 6.1 0.1 2.7 2 0 0 2 2 2 0 HalX domain CCDC-167 PF15188.1 KLO13461.1 - 3.7 7.5 8.0 4.6 7.2 3.8 2.3 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 167 DivIC PF04977.10 KLO13461.1 - 5 6.6 8.5 0.75 9.3 2.7 2.0 1 1 1 2 2 2 0 Septum formation initiator Syntaxin PF00804.20 KLO13461.1 - 5.3 7.2 13.4 2.5 8.2 6.9 2.2 3 0 0 3 3 2 0 Syntaxin Fib_alpha PF08702.5 KLO13463.1 - 0.014 15.5 1.8 1.1 9.3 0.5 2.3 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family DUF2730 PF10805.3 KLO13463.1 - 0.04 13.6 0.7 0.61 9.8 0.0 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF2730) DUF2205 PF10224.4 KLO13463.1 - 0.04 13.4 0.1 8.4 6.0 0.0 2.5 2 0 0 2 2 2 0 Predicted coiled-coil protein (DUF2205) Mis12 PF05859.7 KLO13463.1 - 0.074 12.8 0.2 0.19 11.5 0.1 1.7 1 1 1 2 2 2 0 Mis12 protein Prefoldin_3 PF13758.1 KLO13463.1 - 0.11 12.3 2.5 0.57 9.9 1.7 2.3 1 1 0 1 1 1 0 Prefoldin subunit Laminin_II PF06009.7 KLO13463.1 - 0.69 9.6 4.6 5.6 6.7 0.9 3.2 2 2 1 3 3 3 0 Laminin Domain II NPV_P10 PF05531.7 KLO13463.1 - 0.82 9.9 4.8 1.8 8.8 0.1 2.9 3 1 0 3 3 3 0 Nucleopolyhedrovirus P10 protein End3 PF12761.2 KLO13464.1 - 0.0014 18.3 3.0 0.0024 17.5 2.1 1.4 1 0 0 1 1 1 1 Actin cytoskeleton-regulatory complex protein END3 Mnd1 PF03962.10 KLO13464.1 - 0.011 15.4 6.8 0.011 15.4 4.7 1.9 2 0 0 2 2 2 0 Mnd1 family DegQ PF08181.6 KLO13464.1 - 0.019 14.6 1.0 0.038 13.7 0.1 1.9 2 0 0 2 2 2 0 DegQ (SacQ) family YtfJ_HI0045 PF09695.5 KLO13464.1 - 0.03 13.6 1.1 0.045 13.0 0.8 1.3 1 0 0 1 1 1 0 Bacterial protein of unknown function (YtfJ_HI0045) Syntaxin-6_N PF09177.6 KLO13464.1 - 0.044 14.1 11.3 0.055 13.8 2.3 3.5 2 2 1 3 3 3 0 Syntaxin 6, N-terminal V_ATPase_I PF01496.14 KLO13464.1 - 0.054 11.3 5.5 0.18 9.5 3.9 1.7 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family PAH PF02671.16 KLO13465.1 - 0.0043 16.6 0.2 6.9 6.3 0.0 3.7 2 1 1 3 3 3 2 Paired amphipathic helix repeat Syntaxin PF00804.20 KLO13465.1 - 0.012 15.7 0.1 1.5 9.0 0.1 2.2 2 0 0 2 2 2 0 Syntaxin TPR_11 PF13414.1 KLO13466.1 - 3.5e-28 97.0 0.0 3.4e-10 39.4 0.0 7.0 6 1 3 9 9 9 6 TPR repeat TPR_2 PF07719.12 KLO13466.1 - 9.1e-28 93.9 3.2 0.0018 18.0 0.0 9.3 10 0 0 10 10 9 6 Tetratricopeptide repeat TPR_1 PF00515.23 KLO13466.1 - 9.3e-23 78.8 0.0 2.1e-06 27.0 0.0 8.1 8 0 0 8 8 8 4 Tetratricopeptide repeat Apc3 PF12895.2 KLO13466.1 - 1.5e-20 73.1 2.1 4.5e-08 33.1 0.0 5.9 3 1 3 6 6 6 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.1 KLO13466.1 - 8.1e-20 70.5 2.1 1.5e-07 31.2 0.0 7.9 6 3 2 9 9 9 3 Tetratricopeptide repeat TPR_16 PF13432.1 KLO13466.1 - 2.5e-15 56.6 7.4 0.00017 22.1 0.0 7.8 7 1 1 8 8 8 4 Tetratricopeptide repeat TPR_8 PF13181.1 KLO13466.1 - 4.4e-15 54.2 0.0 0.011 15.4 0.0 7.6 9 0 0 9 9 9 3 Tetratricopeptide repeat TPR_7 PF13176.1 KLO13466.1 - 2.8e-12 45.4 1.1 0.17 11.7 0.0 7.1 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_17 PF13431.1 KLO13466.1 - 1.6e-11 43.4 0.3 0.00083 19.3 0.0 7.3 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_14 PF13428.1 KLO13466.1 - 2e-11 43.4 2.8 0.12 13.0 0.0 7.8 6 2 2 8 8 8 1 Tetratricopeptide repeat TPR_19 PF14559.1 KLO13466.1 - 3.6e-10 40.0 0.3 0.27 11.6 0.0 5.7 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_10 PF13374.1 KLO13466.1 - 7.2e-07 28.9 1.1 24 5.0 0.0 6.8 8 0 0 8 8 8 0 Tetratricopeptide repeat TPR_6 PF13174.1 KLO13466.1 - 0.0014 18.9 17.7 0.75 10.3 0.3 7.1 9 0 0 9 9 7 1 Tetratricopeptide repeat PPR PF01535.15 KLO13466.1 - 0.088 12.8 0.2 12 6.0 0.0 3.5 2 0 0 2 2 2 0 PPR repeat TPR_4 PF07721.9 KLO13466.1 - 0.74 10.4 7.9 0.44 11.1 0.8 4.2 6 0 0 6 6 5 0 Tetratricopeptide repeat TOM13 PF08219.6 KLO13468.1 - 2.7e-14 52.6 0.4 1.4e-13 50.3 0.0 2.3 2 0 0 2 2 2 1 Outer membrane protein TOM13 zf-DNA_Pol PF08996.5 KLO13469.1 - 0.78 9.0 7.8 0.45 9.8 1.7 1.9 1 1 1 2 2 2 0 DNA Polymerase alpha zinc finger XLF PF09302.6 KLO13470.1 - 0.00019 21.2 0.0 0.00031 20.5 0.0 1.4 1 0 0 1 1 1 1 XLF (XRCC4-like factor) FHA PF00498.21 KLO13471.1 - 6.1e-08 32.6 0.0 1.1e-07 31.8 0.0 1.4 1 0 0 1 1 1 1 FHA domain G-patch PF01585.18 KLO13471.1 - 4.6e-06 26.3 0.2 1.3e-05 24.9 0.1 1.8 1 1 0 1 1 1 1 G-patch domain adh_short PF00106.20 KLO13472.1 - 1.5e-63 213.6 17.9 1.5e-33 116.0 2.3 2.6 3 0 0 3 3 3 2 short chain dehydrogenase KR PF08659.5 KLO13472.1 - 1.4e-28 99.8 11.0 3e-14 53.1 2.4 2.3 2 0 0 2 2 2 2 KR domain MaoC_dehydratas PF01575.14 KLO13472.1 - 2.9e-27 94.4 0.0 6.2e-27 93.4 0.0 1.5 1 0 0 1 1 1 1 MaoC like domain MaoC_dehydrat_N PF13452.1 KLO13472.1 - 2e-12 47.0 0.0 4.8e-12 45.7 0.0 1.7 1 0 0 1 1 1 1 N-terminal half of MaoC dehydratase adh_short_C2 PF13561.1 KLO13472.1 - 6.4e-12 45.7 3.2 1e-05 25.4 0.2 2.8 2 1 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase THF_DHG_CYH_C PF02882.14 KLO13472.1 - 0.00025 20.1 1.0 0.036 13.1 0.3 2.4 2 0 0 2 2 2 2 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain 3HCDH_N PF02737.13 KLO13472.1 - 0.0024 17.5 12.1 0.11 12.1 1.7 2.4 2 0 0 2 2 2 2 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Phage_portal_2 PF05136.8 KLO13472.1 - 0.11 10.9 0.0 4 5.8 0.0 2.2 2 0 0 2 2 2 0 Phage portal protein, lambda family Ldh_1_N PF00056.18 KLO13472.1 - 0.15 11.9 8.8 2.3 8.0 1.0 2.5 2 0 0 2 2 2 0 lactate/malate dehydrogenase, NAD binding domain TAP_C PF03943.8 KLO13473.1 - 1.8e-07 30.4 0.0 3.7e-07 29.4 0.0 1.6 1 0 0 1 1 1 1 TAP C-terminal domain LRR_4 PF12799.2 KLO13473.1 - 0.0001 21.8 1.8 0.00023 20.7 0.3 2.3 3 0 0 3 3 3 1 Leucine Rich repeats (2 copies) NTF2 PF02136.15 KLO13473.1 - 0.006 16.9 0.0 0.043 14.1 0.0 2.2 1 1 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain UBA_4 PF14555.1 KLO13473.1 - 0.0097 15.4 0.0 0.02 14.3 0.0 1.5 1 0 0 1 1 1 1 UBA-like domain LRR_8 PF13855.1 KLO13473.1 - 0.05 13.3 0.9 0.18 11.5 0.1 2.2 2 0 0 2 2 2 0 Leucine rich repeat LRR_9 PF14580.1 KLO13473.1 - 0.12 11.8 0.1 0.22 11.0 0.0 1.4 1 0 0 1 1 1 0 Leucine-rich repeat TPK_catalytic PF04263.11 KLO13474.1 - 2.3e-27 95.0 0.1 3.1e-27 94.5 0.1 1.1 1 0 0 1 1 1 1 Thiamin pyrophosphokinase, catalytic domain TPK_B1_binding PF04265.9 KLO13474.1 - 5.9e-18 64.3 0.6 1e-17 63.6 0.4 1.4 1 0 0 1 1 1 1 Thiamin pyrophosphokinase, vitamin B1 binding domain Acyl-CoA_dh_1 PF00441.19 KLO13475.1 - 3.9e-32 111.4 0.2 5.6e-32 110.9 0.1 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Cyt-b5 PF00173.23 KLO13475.1 - 6e-18 64.4 0.0 1.4e-17 63.2 0.0 1.7 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Acyl-CoA_dh_M PF02770.14 KLO13475.1 - 1e-16 60.1 0.5 2.6e-16 58.8 0.3 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.11 KLO13475.1 - 2.8e-12 47.2 0.0 1e-11 45.3 0.0 2.0 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.6 KLO13475.1 - 1.9e-06 28.1 0.3 3.9e-06 27.1 0.0 1.6 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Barstar PF01337.13 KLO13476.1 - 0.049 13.4 0.0 0.66 9.8 0.0 2.6 3 0 0 3 3 3 0 Barstar (barnase inhibitor) Mnd1 PF03962.10 KLO13477.1 - 2.4e-05 24.0 4.9 0.00076 19.2 1.7 2.2 2 0 0 2 2 2 1 Mnd1 family MCPsignal PF00015.16 KLO13477.1 - 0.049 13.1 8.0 3 7.3 0.5 3.1 3 0 0 3 3 3 0 Methyl-accepting chemotaxis protein (MCP) signalling domain DUF1664 PF07889.7 KLO13477.1 - 0.14 11.9 9.0 3 7.6 0.1 3.4 3 1 0 3 3 3 0 Protein of unknown function (DUF1664) DUF342 PF03961.8 KLO13477.1 - 0.2 10.0 5.4 0.094 11.1 2.2 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF342) Fib_alpha PF08702.5 KLO13477.1 - 0.23 11.5 9.2 1.6 8.8 1.0 3.0 3 0 0 3 3 3 0 Fibrinogen alpha/beta chain family EMP24_GP25L PF01105.19 KLO13477.1 - 0.35 10.5 2.9 2.4 7.8 0.0 2.4 2 0 0 2 2 2 0 emp24/gp25L/p24 family/GOLD DivIC PF04977.10 KLO13477.1 - 0.61 9.6 6.0 1.4 8.5 0.1 2.9 2 0 0 2 2 2 0 Septum formation initiator DASH_Dad3 PF08656.5 KLO13477.1 - 0.78 9.4 3.7 0.27 10.9 0.2 2.0 2 0 0 2 2 2 0 DASH complex subunit Dad3 Syntaxin-6_N PF09177.6 KLO13477.1 - 3.7 8.0 12.6 11 6.4 1.0 3.5 2 2 2 4 4 4 0 Syntaxin 6, N-terminal DMPK_coil PF08826.5 KLO13477.1 - 3.9 7.4 11.1 5.8 6.9 2.0 3.4 4 0 0 4 4 3 0 DMPK coiled coil domain like Fzo_mitofusin PF04799.8 KLO13477.1 - 4.2 6.7 7.4 11 5.3 0.0 3.2 3 1 0 3 3 3 0 fzo-like conserved region IncA PF04156.9 KLO13477.1 - 5.6 6.5 13.0 21 4.6 0.1 3.5 3 1 1 4 4 4 0 IncA protein DUF4208 PF13907.1 KLO13478.1 - 0.076 13.2 0.0 8.5 6.6 0.0 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4208) SH3_1 PF00018.23 KLO13480.1 - 1.5e-16 59.4 0.1 2.5e-16 58.7 0.1 1.4 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 KLO13480.1 - 1.9e-12 46.5 0.1 3.5e-12 45.7 0.1 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 KLO13480.1 - 4.6e-11 42.0 0.0 8.7e-11 41.1 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain Pkinase PF00069.20 KLO13481.1 - 1.1e-34 119.7 0.1 1.2e-34 119.6 0.1 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KLO13481.1 - 2.1e-17 63.0 0.0 2.4e-17 62.8 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KLO13481.1 - 1.1e-06 27.8 0.0 1.3e-06 27.6 0.0 1.1 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 KLO13481.1 - 0.00052 19.8 0.4 0.00066 19.4 0.2 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.17 KLO13481.1 - 0.097 12.0 0.1 0.12 11.6 0.0 1.1 1 0 0 1 1 1 0 RIO1 family MaoC_dehydratas PF01575.14 KLO13482.1 - 1.9e-28 98.3 0.0 3.5e-28 97.4 0.0 1.4 1 0 0 1 1 1 1 MaoC like domain MaoC_dehydrat_N PF13452.1 KLO13482.1 - 7.9e-10 38.6 0.0 1.6e-08 34.3 0.0 2.3 2 1 0 2 2 2 1 N-terminal half of MaoC dehydratase Na_Ca_ex PF01699.19 KLO13483.1 - 4e-34 117.2 32.5 2.8e-18 65.8 3.7 3.8 4 0 0 4 4 4 2 Sodium/calcium exchanger protein ST7 PF04184.7 KLO13483.1 - 0.0065 14.7 0.7 0.011 14.0 0.5 1.3 1 0 0 1 1 1 1 ST7 protein NMT PF01233.14 KLO13484.1 - 6.6e-75 250.1 0.0 1e-74 249.5 0.0 1.3 1 0 0 1 1 1 1 Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain NMT_C PF02799.10 KLO13484.1 - 1.9e-67 226.3 0.0 4.3e-67 225.1 0.0 1.6 1 0 0 1 1 1 1 Myristoyl-CoA:protein N-myristoyltransferase, C-terminal domain Acetyltransf_9 PF13527.1 KLO13484.1 - 2.7e-07 30.4 0.0 3.5e-06 26.8 0.0 2.5 3 0 0 3 3 3 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 KLO13484.1 - 0.0046 17.0 0.1 0.015 15.4 0.0 1.9 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 KLO13484.1 - 0.065 13.2 0.1 0.17 11.9 0.0 1.8 2 0 0 2 2 2 0 Acetyltransferase (GNAT) family eIF3_subunit PF08597.5 KLO13484.1 - 0.36 10.3 10.3 0.52 9.8 7.1 1.2 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit Tom37_C PF11801.3 KLO13484.1 - 2.4 8.0 6.1 4.5 7.0 4.2 1.4 1 0 0 1 1 1 0 Tom37 C-terminal domain Ribosomal_L3 PF00297.17 KLO13485.1 - 2.9e-37 128.5 3.0 4.6e-36 124.5 2.1 2.1 1 1 0 1 1 1 1 Ribosomal protein L3 OGG_N PF07934.7 KLO13486.1 - 3e-28 98.1 0.0 4.8e-28 97.4 0.0 1.4 1 0 0 1 1 1 1 8-oxoguanine DNA glycosylase, N-terminal domain HhH-GPD PF00730.20 KLO13486.1 - 4e-13 49.6 0.0 1.6e-12 47.6 0.0 1.9 2 0 0 2 2 2 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.18 KLO13486.1 - 0.00021 20.8 0.0 0.00055 19.4 0.0 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix motif DUF1313 PF07011.6 KLO13486.1 - 0.093 12.4 0.0 0.19 11.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1313) Utp21 PF04192.7 KLO13487.1 - 6.2e-63 212.0 0.0 9.7e-63 211.4 0.0 1.2 1 0 0 1 1 1 1 Utp21 specific WD40 associated putative domain WD40 PF00400.27 KLO13487.1 - 2.9e-24 83.9 11.6 2.1e-06 27.3 0.0 9.4 9 0 0 9 9 9 5 WD domain, G-beta repeat Hira PF07569.6 KLO13487.1 - 0.053 12.7 0.5 8.4 5.5 0.0 3.4 2 1 0 3 3 3 0 TUP1-like enhancer of split Cytochrom_D1 PF02239.11 KLO13487.1 - 0.11 10.7 0.1 0.68 8.1 0.0 2.1 2 0 0 2 2 2 0 Cytochrome D1 heme domain eIF2A PF08662.6 KLO13487.1 - 0.11 12.1 0.0 10 5.7 0.0 3.0 2 1 1 3 3 3 0 Eukaryotic translation initiation factor eIF2A MFS_1 PF07690.11 KLO13488.1 - 2.5e-27 95.5 19.9 2.3e-23 82.4 8.1 2.2 2 0 0 2 2 2 2 Major Facilitator Superfamily SKN1 PF03935.10 KLO13490.1 - 3.2e-189 629.2 2.4 3.7e-189 629.0 1.7 1.0 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) CMD PF02627.15 KLO13491.1 - 1.8e-17 62.9 0.7 8.4e-17 60.7 0.2 1.9 2 0 0 2 2 2 1 Carboxymuconolactone decarboxylase family Anti-adapt_IraP PF10796.4 KLO13491.1 - 0.1 13.0 0.3 0.45 10.9 0.1 2.0 2 0 0 2 2 2 0 Sigma-S stabilisation anti-adaptor protein Cofilin_ADF PF00241.15 KLO13492.1 - 1.2e-05 25.2 0.0 1.6e-05 24.7 0.0 1.4 1 1 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein Phage_X PF05155.10 KLO13492.1 - 0.031 14.1 0.0 0.064 13.1 0.0 1.5 1 1 0 1 1 1 0 Phage X family EF-hand_1 PF00036.27 KLO13492.1 - 0.087 12.1 0.0 0.25 10.7 0.0 1.8 1 0 0 1 1 1 0 EF hand Mannosyl_trans PF05007.8 KLO13493.1 - 2.3e-64 217.5 18.9 2.3e-63 214.2 13.1 2.1 1 1 0 1 1 1 1 Mannosyltransferase (PIG-M) PIG-U PF06728.8 KLO13493.1 - 2.9e-17 62.5 10.0 2.9e-17 62.5 6.9 2.1 3 0 0 3 3 3 1 GPI transamidase subunit PIG-U DUF1045 PF06299.7 KLO13493.1 - 0.037 13.7 0.7 0.086 12.5 0.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1045) RabGAP-TBC PF00566.13 KLO13494.1 - 3.1e-41 141.2 2.8 1.4e-38 132.5 0.5 2.3 2 0 0 2 2 2 2 Rab-GTPase-TBC domain DUF3548 PF12068.3 KLO13494.1 - 1.2e-07 31.2 0.1 0.29 10.4 0.1 3.4 2 1 1 3 3 3 3 Domain of unknown function (DUF3548) Lung_7-TM_R PF06814.8 KLO13494.1 - 0.099 11.5 0.8 0.15 10.9 0.6 1.2 1 0 0 1 1 1 0 Lung seven transmembrane receptor Exo_endo_phos PF03372.18 KLO13495.1 - 1.5e-18 67.6 0.0 2e-18 67.2 0.0 1.1 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family NAD_binding_2 PF03446.10 KLO13496.1 - 8.9e-37 126.4 0.0 1.2e-36 125.9 0.0 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.1 KLO13496.1 - 1.6e-28 99.2 0.0 2.5e-28 98.5 0.0 1.4 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase OCD_Mu_crystall PF02423.10 KLO13496.1 - 1.9e-05 23.5 0.0 3e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 Ornithine cyclodeaminase/mu-crystallin family F420_oxidored PF03807.12 KLO13496.1 - 0.0013 19.0 0.0 0.014 15.8 0.0 2.5 3 0 0 3 3 3 1 NADP oxidoreductase coenzyme F420-dependent GFO_IDH_MocA PF01408.17 KLO13496.1 - 0.024 15.1 0.0 0.087 13.3 0.0 1.8 2 0 0 2 2 2 0 Oxidoreductase family, NAD-binding Rossmann fold CAAD PF14159.1 KLO13496.1 - 0.11 12.2 0.0 0.2 11.3 0.0 1.4 1 0 0 1 1 1 0 CAAD domains of cyanobacterial aminoacyl-tRNA synthetase Med29 PF11568.3 KLO13497.1 - 0.07 13.1 0.1 0.11 12.5 0.1 1.4 1 1 0 1 1 1 0 Mediator complex subunit 29 Acetyltransf_1 PF00583.19 KLO13499.1 - 3.8e-12 46.0 0.2 1.4e-11 44.2 0.2 1.9 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 KLO13499.1 - 9e-07 28.9 0.3 2.7e-05 24.2 0.0 2.8 3 0 0 3 3 3 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 KLO13499.1 - 1.7e-05 24.7 0.0 2.2e-05 24.3 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 KLO13499.1 - 0.00011 22.4 0.0 0.00018 21.7 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 KLO13499.1 - 0.00011 21.8 0.0 0.00022 20.9 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.1 KLO13499.1 - 0.00014 21.9 0.0 0.0006 19.9 0.0 1.9 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 KLO13499.1 - 0.046 13.6 0.0 0.078 12.9 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain MOZ_SAS PF01853.13 KLO13499.1 - 0.07 12.3 0.0 0.11 11.6 0.0 1.2 1 0 0 1 1 1 0 MOZ/SAS family Acetyltransf_CG PF14542.1 KLO13499.1 - 0.11 12.3 0.0 0.28 11.1 0.0 1.6 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase DUF4231 PF14015.1 KLO13500.1 - 0.076 12.9 1.9 0.097 12.6 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF4231) DASH_Spc34 PF08657.5 KLO13500.1 - 0.099 12.2 0.5 0.61 9.6 0.0 2.2 2 1 0 2 2 2 0 DASH complex subunit Spc34 Zw10 PF06248.8 KLO13500.1 - 0.15 10.1 0.0 0.21 9.7 0.0 1.2 1 0 0 1 1 1 0 Centromere/kinetochore Zw10 Arf PF00025.16 KLO13501.1 - 1e-65 220.2 0.0 1.2e-65 220.0 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.15 KLO13501.1 - 1.7e-09 36.9 0.1 4e-06 25.7 0.0 2.3 1 1 1 2 2 2 2 G-protein alpha subunit SRPRB PF09439.5 KLO13501.1 - 1.4e-08 34.1 0.0 1.8e-08 33.8 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.18 KLO13501.1 - 1.5e-07 31.3 0.0 3.3e-07 30.2 0.0 1.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase Ras PF00071.17 KLO13501.1 - 1.9e-07 30.6 0.0 2.3e-07 30.3 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KLO13501.1 - 6.2e-07 29.9 0.0 8.8e-07 29.4 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Gtr1_RagA PF04670.7 KLO13501.1 - 0.00017 20.7 0.0 0.0002 20.6 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region PduV-EutP PF10662.4 KLO13501.1 - 0.0057 16.1 0.0 0.052 13.0 0.0 2.4 2 1 1 3 3 3 1 Ethanolamine utilisation - propanediol utilisation GTP_EFTU PF00009.22 KLO13501.1 - 0.0077 15.6 0.0 0.23 10.8 0.0 2.1 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain SRPRB PF09439.5 KLO13502.1 - 1.3e-20 73.4 0.0 2.8e-20 72.2 0.0 1.5 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit Arf PF00025.16 KLO13502.1 - 4.3e-13 48.8 0.0 6.7e-13 48.2 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 KLO13502.1 - 2.1e-09 36.8 0.0 3.1e-09 36.3 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 KLO13502.1 - 2.1e-06 28.2 0.0 4.1e-06 27.2 0.0 1.5 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 KLO13502.1 - 2.9e-06 27.2 0.0 4.6e-06 26.5 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.18 KLO13502.1 - 0.00022 21.1 0.1 0.23 11.2 0.0 2.3 1 1 1 2 2 2 2 Dynamin family G-alpha PF00503.15 KLO13502.1 - 0.0011 17.7 0.1 0.59 8.7 0.0 2.2 1 1 1 2 2 2 2 G-protein alpha subunit Ras PF00071.17 KLO13502.1 - 0.003 16.9 0.0 0.0039 16.5 0.0 1.2 1 0 0 1 1 1 1 Ras family FeoB_N PF02421.13 KLO13502.1 - 0.009 15.3 0.0 0.021 14.0 0.0 1.6 1 1 0 1 1 1 1 Ferrous iron transport protein B ATP_bind_1 PF03029.12 KLO13502.1 - 0.034 13.6 0.1 0.34 10.4 0.0 2.0 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein FixQ PF05545.6 KLO13502.1 - 0.036 13.7 0.4 0.083 12.5 0.3 1.5 1 0 0 1 1 1 0 Cbb3-type cytochrome oxidase component FixQ GTP_EFTU PF00009.22 KLO13502.1 - 0.061 12.7 0.4 5.6 6.3 0.0 2.2 1 1 1 2 2 2 0 Elongation factor Tu GTP binding domain AAA_25 PF13481.1 KLO13502.1 - 0.076 12.4 0.0 0.17 11.3 0.0 1.6 1 1 0 1 1 1 0 AAA domain SUI1 PF01253.17 KLO13503.1 - 2.4e-17 62.5 0.1 9.3e-17 60.6 0.0 1.9 2 0 0 2 2 2 1 Translation initiation factor SUI1 PAP2 PF01569.16 KLO13504.1 - 2.2e-27 95.2 1.7 5.1e-27 94.0 1.2 1.5 1 0 0 1 1 1 1 PAP2 superfamily PPP4R2 PF09184.6 KLO13505.1 - 9.4e-20 71.3 0.1 9.4e-20 71.3 0.0 1.8 2 1 0 2 2 2 1 PPP4R2 DUF1777 PF08648.7 KLO13506.1 - 1.5e-26 93.2 23.1 3e-26 92.2 16.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1777) RRM_6 PF14259.1 KLO13507.1 - 1.3e-10 41.1 0.0 4.8e-07 29.6 0.0 2.7 2 1 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 KLO13507.1 - 0.0018 17.8 0.0 0.05 13.2 0.0 2.9 3 1 0 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 KLO13508.1 - 4.9e-15 54.9 0.0 1.4e-14 53.4 0.0 1.7 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KLO13508.1 - 2.6e-12 46.5 0.0 3.9e-12 45.9 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KLO13508.1 - 5.6e-08 32.5 0.1 1.4e-07 31.1 0.0 1.7 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) WD40 PF00400.27 KLO13509.1 - 1.3e-08 34.3 2.5 0.18 11.7 0.0 4.6 5 0 0 5 5 5 3 WD domain, G-beta repeat IKI3 PF04762.7 KLO13509.1 - 0.15 9.7 0.0 0.93 7.2 0.1 2.0 2 1 0 2 2 2 0 IKI3 family NHL PF01436.16 KLO13509.1 - 4.9 7.3 7.0 12 6.0 0.2 3.3 3 0 0 3 3 3 0 NHL repeat CASP_C PF08172.7 KLO13510.1 - 0.0028 16.7 1.1 0.0039 16.2 0.8 1.2 1 0 0 1 1 1 1 CASP C terminal TraT PF05818.7 KLO13510.1 - 0.0045 16.4 0.8 0.0075 15.7 0.5 1.3 1 0 0 1 1 1 1 Enterobacterial TraT complement resistance protein Fusion_gly PF00523.13 KLO13510.1 - 0.19 9.7 0.7 0.25 9.3 0.5 1.1 1 0 0 1 1 1 0 Fusion glycoprotein F0 Bacteriocin_IIc PF10439.4 KLO13510.1 - 2.4 8.3 9.2 0.42 10.7 2.3 2.3 2 1 0 2 2 2 0 Bacteriocin class II with double-glycine leader peptide DcpS_C PF11969.3 KLO13511.1 - 1.9e-15 57.1 0.4 3.2e-15 56.3 0.3 1.4 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding HIT PF01230.18 KLO13511.1 - 5.6e-12 46.0 0.1 1.2e-11 44.9 0.0 1.5 1 0 0 1 1 1 1 HIT domain FYDLN_acid PF09538.5 KLO13511.1 - 0.0089 16.5 1.1 0.0089 16.5 0.7 2.0 2 0 0 2 2 2 1 Protein of unknown function (FYDLN_acid) zf-C2H2_4 PF13894.1 KLO13511.1 - 0.021 15.1 0.2 0.073 13.4 0.1 1.8 1 0 0 1 1 1 0 C2H2-type zinc finger Relaxase PF03432.9 KLO13511.1 - 0.44 9.8 10.0 3.6 6.8 6.4 2.5 1 1 0 1 1 1 0 Relaxase/Mobilisation nuclease domain PIG-Y PF15159.1 KLO13512.1 - 3.5e-07 30.3 4.3 4.7e-07 29.9 3.0 1.1 1 0 0 1 1 1 1 Phosphatidylinositol N-acetylglucosaminyltransferase subunit Y CoxIIa PF08113.6 KLO13512.1 - 1.9 8.3 5.7 0.22 11.2 0.8 1.8 2 0 0 2 2 2 0 Cytochrome c oxidase subunit IIa family Tetraspannin PF00335.15 KLO13512.1 - 4.4 6.5 6.9 5.5 6.2 4.8 1.0 1 0 0 1 1 1 0 Tetraspanin family ADH_N PF08240.7 KLO13513.1 - 7.8e-29 99.6 0.6 7.8e-29 99.6 0.4 1.6 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KLO13513.1 - 5.9e-12 45.2 0.1 1.5e-11 43.9 0.1 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_assoc PF13823.1 KLO13513.1 - 0.00053 19.5 0.1 0.0013 18.3 0.1 1.8 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-associated HI0933_like PF03486.9 KLO13513.1 - 0.00064 18.2 0.3 0.0021 16.5 0.0 1.8 2 0 0 2 2 2 1 HI0933-like protein Methyltransf_18 PF12847.2 KLO13513.1 - 0.005 17.3 0.0 0.014 16.0 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Pyr_redox PF00070.22 KLO13513.1 - 0.0077 16.6 0.3 0.22 11.9 0.1 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.16 KLO13513.1 - 0.0097 15.4 0.1 0.017 14.7 0.1 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain TrkA_N PF02254.13 KLO13513.1 - 0.017 15.1 0.0 0.027 14.4 0.0 1.3 1 0 0 1 1 1 0 TrkA-N domain Pyr_redox_3 PF13738.1 KLO13513.1 - 0.033 14.2 0.1 0.055 13.5 0.1 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 KLO13513.1 - 0.039 12.8 0.1 0.065 12.1 0.1 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase 3HCDH_N PF02737.13 KLO13513.1 - 0.054 13.1 0.1 0.074 12.7 0.1 1.2 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ApbA PF02558.11 KLO13513.1 - 0.067 12.6 0.0 0.14 11.5 0.0 1.6 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA FAD_binding_3 PF01494.14 KLO13513.1 - 0.069 12.1 0.1 0.11 11.5 0.1 1.2 1 0 0 1 1 1 0 FAD binding domain Methyltransf_31 PF13847.1 KLO13513.1 - 0.07 12.7 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Shikimate_DH PF01488.15 KLO13513.1 - 0.08 13.0 0.0 0.15 12.1 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase UDPG_MGDP_dh_N PF03721.9 KLO13513.1 - 0.11 11.9 0.0 0.17 11.2 0.0 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain SUI1 PF01253.17 KLO13514.1 - 9.1e-28 95.8 1.4 1.1e-27 95.6 1.0 1.1 1 0 0 1 1 1 1 Translation initiation factor SUI1 DNA_Packaging PF11053.3 KLO13515.1 - 0.064 12.8 0.0 0.16 11.5 0.0 1.7 1 0 0 1 1 1 0 Terminase DNA packaging enzyme rRNA_processing PF08524.6 KLO13515.1 - 2.3 8.0 25.0 5 6.9 1.7 2.9 1 1 0 2 2 2 0 rRNA processing ATP1G1_PLM_MAT8 PF02038.11 KLO13516.1 - 0.06 12.3 1.4 0.13 11.3 0.9 1.5 1 0 0 1 1 1 0 ATP1G1/PLM/MAT8 family RicinB_lectin_2 PF14200.1 KLO13521.1 - 8.8e-07 29.2 0.0 1.5e-05 25.3 0.0 2.0 1 1 0 2 2 2 1 Ricin-type beta-trefoil lectin domain-like DUF3408 PF11888.3 KLO13522.1 - 0.017 15.0 0.3 0.017 15.0 0.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3408) Imm42 PF15601.1 KLO13522.1 - 0.082 12.3 0.0 0.17 11.2 0.0 1.4 1 0 0 1 1 1 0 Immunity protein 42 DUF2040 PF09745.4 KLO13523.1 - 3e-36 124.0 25.4 3e-36 124.0 17.6 2.7 2 1 0 2 2 2 1 Coiled-coil domain-containing protein 55 (DUF2040) Pkinase PF00069.20 KLO13524.1 - 2.3e-10 40.0 0.0 1.2e-09 37.6 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain APH PF01636.18 KLO13524.1 - 0.0034 17.1 0.0 0.0065 16.2 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_Tyr PF07714.12 KLO13524.1 - 0.0088 15.1 0.0 0.02 13.9 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase PBP1_TM PF14812.1 KLO13524.1 - 0.26 11.6 3.2 0.52 10.6 2.2 1.4 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal TFIID-18kDa PF02269.11 KLO13525.1 - 2.6e-21 75.2 0.2 2.9e-21 75.0 0.1 1.0 1 0 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit CBFD_NFYB_HMF PF00808.18 KLO13525.1 - 0.058 13.4 0.0 0.088 12.8 0.0 1.4 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone RRM_1 PF00076.17 KLO13526.1 - 6e-14 51.4 0.2 3.1e-12 45.9 0.2 2.2 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KLO13526.1 - 8.6e-13 48.0 0.0 1.5e-12 47.2 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KLO13526.1 - 4.3e-07 29.6 0.0 1.9e-05 24.4 0.0 2.1 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM PF05172.8 KLO13526.1 - 0.0016 18.1 0.0 0.0024 17.5 0.0 1.3 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif Nup35_RRM_2 PF14605.1 KLO13526.1 - 0.046 13.5 0.0 0.068 12.9 0.0 1.3 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif DUF2315 PF10231.4 KLO13527.1 - 2.9e-15 56.2 5.9 2.3e-12 46.9 1.3 2.2 2 0 0 2 2 2 2 Uncharacterised conserved protein (DUF2315) Nucleoporin_C PF03177.9 KLO13528.1 - 9.8e-58 196.0 1.0 2e-57 195.0 0.7 1.4 1 1 0 1 1 1 1 Non-repetitive/WGA-negative nucleoporin C-terminal Nucleoporin_N PF08801.6 KLO13528.1 - 5.6e-15 55.0 0.0 8.5e-15 54.4 0.0 1.2 1 0 0 1 1 1 1 Nup133 N terminal like NSP13 PF06460.7 KLO13528.1 - 0.019 13.8 0.0 0.032 13.1 0.0 1.2 1 0 0 1 1 1 0 Coronavirus NSP13 AA_permease_2 PF13520.1 KLO13529.1 - 2.4e-66 224.0 42.6 3e-66 223.7 29.6 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 KLO13529.1 - 3.4e-28 98.2 37.1 1.4e-27 96.2 26.0 1.4 1 1 1 2 2 2 1 Amino acid permease NAD_binding_6 PF08030.7 KLO13530.1 - 7.7e-19 68.1 0.0 2.5e-11 43.7 0.0 2.3 2 0 0 2 2 2 2 Ferric reductase NAD binding domain Ferric_reduct PF01794.14 KLO13530.1 - 1.2e-13 51.2 11.3 1.2e-13 51.2 7.9 2.5 2 0 0 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.7 KLO13530.1 - 4.5e-11 42.5 0.0 8.7e-10 38.4 0.0 2.5 1 1 0 1 1 1 1 FAD-binding domain Alpha-amylase PF00128.19 KLO13531.1 - 5.2e-21 75.3 12.3 2.3e-20 73.2 0.3 4.2 4 1 0 4 4 4 2 Alpha amylase, catalytic domain Glyco_transf_5 PF08323.6 KLO13531.1 - 4.8e-15 55.7 0.0 8.3e-15 54.9 0.0 1.3 1 0 0 1 1 1 1 Starch synthase catalytic domain Glycos_transf_1 PF00534.15 KLO13531.1 - 2.1e-08 33.8 0.0 3.8e-08 32.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.1 KLO13531.1 - 2.8e-08 33.9 0.0 7.1e-08 32.6 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 Transmemb_17 PF09799.4 KLO13532.1 - 0.068 13.5 0.1 0.079 13.2 0.1 1.1 1 0 0 1 1 1 0 Predicted membrane protein DUF825 PF05695.7 KLO13532.1 - 0.1 9.9 0.1 0.1 10.0 0.0 1.0 1 0 0 1 1 1 0 Plant protein of unknown function (DUF825) Pkinase PF00069.20 KLO13533.1 - 5.6e-69 232.1 0.0 9e-69 231.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KLO13533.1 - 4.1e-46 157.1 0.0 6.3e-46 156.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Ras_bdg_2 PF14847.1 KLO13533.1 - 1.1e-13 51.0 0.0 2.2e-13 50.0 0.0 1.5 1 0 0 1 1 1 1 Ras-binding domain of Byr2 SAM_2 PF07647.12 KLO13533.1 - 2.3e-10 40.1 0.0 5.8e-10 38.8 0.0 1.7 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.25 KLO13533.1 - 2.1e-08 34.2 0.0 3.8e-08 33.3 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Kinase-like PF14531.1 KLO13533.1 - 0.00015 20.8 0.0 0.00078 18.4 0.0 2.0 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 KLO13533.1 - 0.22 10.5 0.0 0.46 9.5 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RRN3 PF05327.6 KLO13533.1 - 0.36 8.9 0.2 0.65 8.0 0.1 1.4 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 TRM PF02005.11 KLO13534.1 - 9e-113 377.0 0.0 1e-86 291.2 0.0 2.0 2 0 0 2 2 2 2 N2,N2-dimethylguanosine tRNA methyltransferase FCP1_C PF09309.5 KLO13534.1 - 0.0041 16.4 8.8 0.0077 15.5 6.1 1.4 1 0 0 1 1 1 1 FCP1, C-terminal Methyltransf_26 PF13659.1 KLO13534.1 - 0.016 15.2 0.0 0.028 14.4 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Histone PF00125.19 KLO13535.1 - 3e-22 78.5 0.3 4.4e-22 77.9 0.2 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 KLO13535.1 - 2.1e-06 27.6 0.1 5.8e-06 26.2 0.1 1.7 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.8 KLO13535.1 - 0.00027 21.1 0.0 0.00043 20.5 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A Bt_P21 PF05560.6 KLO13535.1 - 0.06 12.7 0.1 0.076 12.3 0.0 1.2 1 0 0 1 1 1 0 Bacillus thuringiensis P21 molecular chaperone protein DUF1018 PF06252.7 KLO13535.1 - 0.11 13.0 0.2 0.14 12.7 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1018) ox_reductase_C PF08635.5 KLO13536.1 - 5.6e-75 249.4 0.1 8e-75 249.0 0.0 1.2 1 0 0 1 1 1 1 Putative oxidoreductase C terminal GFO_IDH_MocA PF01408.17 KLO13536.1 - 1.2e-22 80.6 0.0 2e-22 79.9 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 KLO13536.1 - 0.014 15.1 0.0 0.028 14.2 0.0 1.6 1 0 0 1 1 1 0 Oxidoreductase family, C-terminal alpha/beta domain Nsp1_C PF05064.8 KLO13537.1 - 0.014 14.9 0.1 0.019 14.6 0.0 1.2 1 0 0 1 1 1 0 Nsp1-like C-terminal region V_ATPase_I PF01496.14 KLO13537.1 - 0.037 11.8 4.7 0.047 11.5 3.3 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family EMP24_GP25L PF01105.19 KLO13537.1 - 0.1 12.2 1.4 0.15 11.7 1.0 1.3 1 0 0 1 1 1 0 emp24/gp25L/p24 family/GOLD DUF4140 PF13600.1 KLO13537.1 - 0.11 12.9 2.7 0.24 11.8 1.9 1.6 1 0 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) SYF2 PF08231.7 KLO13537.1 - 0.15 12.2 6.3 0.038 14.1 1.7 1.7 2 0 0 2 2 2 0 SYF2 splicing factor DUF972 PF06156.8 KLO13537.1 - 0.42 10.9 7.4 0.08 13.3 2.7 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF972) IncA PF04156.9 KLO13537.1 - 0.53 9.8 7.9 0.056 13.0 2.8 1.4 2 0 0 2 2 2 0 IncA protein DUF4019 PF13211.1 KLO13537.1 - 0.57 10.4 5.0 0.22 11.7 0.8 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF4019) Fmp27_WPPW PF10359.4 KLO13537.1 - 0.58 8.5 6.3 0.89 7.8 4.3 1.2 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain Herpes_UL6 PF01763.11 KLO13537.1 - 0.98 7.5 5.2 1.4 7.0 3.6 1.1 1 0 0 1 1 1 0 Herpesvirus UL6 like bZIP_Maf PF03131.12 KLO13537.1 - 1.2 9.4 12.1 0.11 12.7 4.8 2.0 2 0 0 2 2 2 0 bZIP Maf transcription factor DUF4407 PF14362.1 KLO13537.1 - 6.4 5.6 9.0 6.5 5.6 6.2 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) RNase_PH PF01138.16 KLO13538.1 - 1.6e-32 112.5 0.1 2.3e-32 112.0 0.0 1.2 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.10 KLO13538.1 - 0.0031 17.4 0.1 0.0053 16.6 0.0 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 F-box-like PF12937.2 KLO13539.1 - 3.2e-07 29.9 1.7 1.2e-06 28.1 1.2 2.0 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KLO13539.1 - 3.9e-05 23.1 0.7 8.7e-05 22.0 0.5 1.5 1 0 0 1 1 1 1 F-box domain Glyco_hydro_61 PF03443.9 KLO13540.1 - 3.1e-44 151.4 0.0 3.7e-44 151.1 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Methyltransf_11 PF08241.7 KLO13541.1 - 2e-13 50.6 0.0 4e-13 49.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KLO13541.1 - 1.8e-11 43.9 0.0 2.6e-11 43.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KLO13541.1 - 3.3e-08 33.9 0.0 1.5e-07 31.8 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 KLO13541.1 - 8.5e-08 32.7 0.0 2.1e-07 31.5 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 KLO13541.1 - 8.9e-06 25.3 0.0 0.0074 15.8 0.0 2.3 2 1 0 2 2 2 2 Methyltransferase domain Methyltransf_26 PF13659.1 KLO13541.1 - 0.00024 21.0 0.0 0.00066 19.6 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KLO13541.1 - 0.00061 20.1 0.0 0.0015 18.8 0.0 1.7 2 0 0 2 2 1 1 Methyltransferase domain RrnaAD PF00398.15 KLO13541.1 - 0.00076 18.5 0.0 0.0011 18.0 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Ubie_methyltran PF01209.13 KLO13541.1 - 0.0018 17.4 0.0 0.0036 16.4 0.0 1.5 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_24 PF13578.1 KLO13541.1 - 0.11 13.2 0.0 0.25 12.1 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain FtsJ PF01728.14 KLO13541.1 - 0.12 12.3 0.0 0.74 9.7 0.0 2.0 1 1 0 1 1 1 0 FtsJ-like methyltransferase Methyltransf_16 PF10294.4 KLO13541.1 - 0.13 11.7 0.0 0.26 10.7 0.0 1.4 1 0 0 1 1 1 0 Putative methyltransferase MTS PF05175.9 KLO13541.1 - 0.16 11.3 0.0 0.49 9.7 0.0 1.8 1 1 0 1 1 1 0 Methyltransferase small domain MaoC_dehydrat_N PF13452.1 KLO13542.1 - 0.0078 15.9 0.0 0.044 13.5 0.0 2.0 2 0 0 2 2 2 1 N-terminal half of MaoC dehydratase PRCC PF10253.4 KLO13543.1 - 1.5e-26 94.1 1.1 1.5e-26 94.1 0.8 2.3 1 1 1 2 2 2 1 Mitotic checkpoint regulator, MAD2B-interacting DAGK_cat PF00781.19 KLO13544.1 - 3e-20 71.9 0.0 5.2e-20 71.2 0.0 1.4 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain SAP PF02037.22 KLO13545.1 - 1.7e-10 40.1 0.2 2.8e-10 39.4 0.2 1.4 1 0 0 1 1 1 1 SAP domain Rho_N PF07498.7 KLO13545.1 - 0.029 14.1 0.1 0.06 13.1 0.1 1.5 1 0 0 1 1 1 0 Rho termination factor, N-terminal domain Methyltransf_11 PF08241.7 KLO13548.1 - 2e-11 44.2 0.0 4.8e-11 43.0 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 KLO13548.1 - 3.4e-08 33.3 0.0 4.7e-08 32.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KLO13548.1 - 5.2e-07 30.2 0.0 6e-06 26.8 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 KLO13548.1 - 6.1e-05 23.4 0.0 0.00012 22.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KLO13548.1 - 6.5e-05 22.9 0.1 0.00021 21.3 0.1 1.9 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KLO13548.1 - 0.0002 20.5 0.0 0.0003 19.9 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.1 KLO13548.1 - 0.0014 18.2 0.0 0.44 10.1 0.0 2.4 2 1 0 2 2 2 2 Methyltransferase domain Methyltransf_11 PF08241.7 KLO13549.1 - 4e-14 52.8 0.0 1e-13 51.5 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 KLO13549.1 - 2.7e-12 46.7 0.0 3.5e-12 46.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KLO13549.1 - 3.9e-08 33.6 0.0 1.3e-07 31.9 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.13 KLO13549.1 - 7.1e-08 31.8 0.0 1.2e-07 31.1 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.1 KLO13549.1 - 1.2e-06 28.8 0.0 5.4e-06 26.7 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 KLO13549.1 - 1.3e-06 28.9 0.0 3.2e-06 27.6 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 KLO13549.1 - 2.2e-06 27.7 0.0 4.2e-06 26.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KLO13549.1 - 1e-05 25.1 0.0 1.4e-05 24.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain RrnaAD PF00398.15 KLO13549.1 - 0.00051 19.1 0.0 0.022 13.7 0.0 2.1 2 0 0 2 2 2 1 Ribosomal RNA adenine dimethylase Methyltransf_24 PF13578.1 KLO13549.1 - 0.00097 19.9 0.1 0.0024 18.7 0.0 1.6 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_16 PF10294.4 KLO13549.1 - 0.052 13.0 0.0 0.086 12.2 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase CDC45 PF02724.9 KLO13550.1 - 3e-186 620.1 0.0 3.7e-186 619.8 0.0 1.0 1 0 0 1 1 1 1 CDC45-like protein IFT57 PF10498.4 KLO13550.1 - 0.26 9.9 1.1 0.55 8.9 0.7 1.5 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 Nucleoplasmin PF03066.10 KLO13550.1 - 1.1 8.7 7.4 2.6 7.5 5.2 1.5 1 0 0 1 1 1 0 Nucleoplasmin Cofilin_ADF PF00241.15 KLO13551.1 - 7.4e-27 93.7 0.0 1.8e-12 47.2 0.0 2.2 2 0 0 2 2 2 2 Cofilin/tropomyosin-type actin-binding protein WD40 PF00400.27 KLO13552.1 - 0.0001 22.0 10.3 0.047 13.5 0.0 4.4 5 0 0 5 5 5 3 WD domain, G-beta repeat zf-C2H2 PF00096.21 KLO13553.1 - 8.1e-06 25.8 5.1 0.0049 17.1 0.4 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KLO13553.1 - 1.8e-05 24.7 4.7 0.004 17.3 0.1 3.0 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 KLO13553.1 - 0.00027 20.9 1.7 0.0057 16.7 0.4 2.6 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 KLO13553.1 - 0.012 15.8 0.1 1.1 9.5 0.0 2.9 2 0 0 2 2 2 0 Zinc-finger of C2H2 type PCNP PF15473.1 KLO13553.1 - 0.016 15.5 1.4 0.04 14.2 0.4 2.1 1 1 1 2 2 2 0 PEST, proteolytic signal-containing nuclear protein family zf-RING_3 PF14369.1 KLO13553.1 - 0.03 14.3 1.6 0.11 12.4 1.1 2.1 1 0 0 1 1 1 0 zinc-finger DUF3272 PF11676.3 KLO13555.1 - 0.017 15.0 3.7 0.51 10.3 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3272) Glyco_hydro_30 PF02055.11 KLO13556.1 - 9.7e-27 93.3 0.3 1.3e-26 92.9 0.2 1.1 1 0 0 1 1 1 1 O-Glycosyl hydrolase family 30 Sod_Fe_C PF02777.13 KLO13557.1 - 1e-37 128.2 0.1 1.7e-37 127.4 0.1 1.3 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.17 KLO13557.1 - 3.1e-32 110.6 3.5 3.1e-32 110.6 2.4 1.7 2 0 0 2 2 2 1 Iron/manganese superoxide dismutases, alpha-hairpin domain AsmA_1 PF13109.1 KLO13557.1 - 0.0051 16.1 0.0 0.073 12.3 0.0 2.2 1 1 1 2 2 2 1 AsmA-like C-terminal region G_glu_transpept PF01019.16 KLO13558.1 - 1.3e-149 498.9 0.0 1.5e-149 498.7 0.0 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase WD40 PF00400.27 KLO13559.1 - 1.1e-65 215.2 15.6 6.1e-14 51.2 0.4 5.7 5 0 0 5 5 5 5 WD domain, G-beta repeat eIF2A PF08662.6 KLO13559.1 - 2.7e-10 40.2 1.2 0.00025 20.8 0.0 3.2 1 1 3 4 4 4 4 Eukaryotic translation initiation factor eIF2A PD40 PF07676.7 KLO13559.1 - 1e-08 34.6 0.4 0.81 9.4 0.0 5.5 5 0 0 5 5 5 2 WD40-like Beta Propeller Repeat Nup160 PF11715.3 KLO13559.1 - 7.3e-06 24.3 7.1 0.012 13.7 0.0 4.1 1 1 2 3 3 3 3 Nucleoporin Nup120/160 PQQ_3 PF13570.1 KLO13559.1 - 2.9e-05 24.1 9.4 1.1 9.5 0.0 5.2 4 1 1 5 5 5 2 PQQ-like domain Nucleoporin_N PF08801.6 KLO13559.1 - 7.8e-05 21.5 2.1 0.26 10.0 0.4 3.8 1 1 0 2 2 2 2 Nup133 N terminal like Cytochrom_D1 PF02239.11 KLO13559.1 - 0.00012 20.5 1.8 0.0079 14.5 0.2 2.9 1 1 2 3 3 3 2 Cytochrome D1 heme domain MMS1_N PF10433.4 KLO13559.1 - 0.00016 19.9 0.0 0.67 8.0 0.0 3.0 1 1 1 3 3 3 2 Mono-functional DNA-alkylating methyl methanesulfonate N-term Proteasome_A_N PF10584.4 KLO13559.1 - 0.00016 20.9 0.3 54 3.2 0.0 5.8 6 0 0 6 6 6 0 Proteasome subunit A N-terminal signature PQQ_2 PF13360.1 KLO13559.1 - 0.00089 18.7 10.6 0.019 14.4 7.4 3.1 1 1 0 1 1 1 1 PQQ-like domain DsbC_N PF10411.4 KLO13559.1 - 0.054 12.7 0.2 60 3.0 0.0 4.2 5 0 0 5 5 5 0 Disulfide bond isomerase protein N-terminus HPS3_N PF14761.1 KLO13559.1 - 0.12 11.7 0.0 1.6 8.0 0.0 2.6 1 1 2 3 3 3 0 Hermansky-Pudlak syndrome 3 PQQ PF01011.16 KLO13559.1 - 0.25 10.9 6.9 22 4.7 0.0 4.7 5 1 1 6 6 6 0 PQQ enzyme repeat Tox-PL PF15644.1 KLO13559.1 - 5.9 7.6 14.5 7.1 7.4 0.3 5.0 2 2 0 2 2 2 0 Papain fold toxin 1 NACHT PF05729.7 KLO13560.1 - 2.6e-06 27.2 0.8 1.1e-05 25.1 0.6 2.3 1 1 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 KLO13560.1 - 3.2e-05 23.9 0.0 8.3e-05 22.6 0.0 1.6 1 1 0 1 1 1 1 AAA ATPase domain AAA PF00004.24 KLO13560.1 - 0.00055 20.1 0.0 0.0014 18.8 0.0 1.6 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 KLO13560.1 - 0.001 19.2 0.0 0.0017 18.5 0.0 1.3 1 1 0 1 1 1 1 AAA domain RNA_helicase PF00910.17 KLO13560.1 - 0.045 13.9 0.0 0.074 13.2 0.0 1.5 1 0 0 1 1 1 0 RNA helicase Arch_ATPase PF01637.13 KLO13560.1 - 0.063 12.9 0.0 0.12 12.0 0.0 1.6 1 1 0 1 1 1 0 Archaeal ATPase AAA_19 PF13245.1 KLO13560.1 - 0.091 12.5 0.0 0.19 11.5 0.0 1.6 2 1 0 2 2 2 0 Part of AAA domain AAA_18 PF13238.1 KLO13560.1 - 0.12 12.6 0.1 0.41 10.9 0.0 1.7 1 1 0 1 1 1 0 AAA domain FANCI_S1 PF14675.1 KLO13560.1 - 0.13 11.6 0.0 0.15 11.3 0.0 1.2 1 0 0 1 1 1 0 FANCI solenoid 1 AAA_30 PF13604.1 KLO13560.1 - 0.13 11.8 0.0 0.23 11.0 0.0 1.6 1 1 0 1 1 1 0 AAA domain NB-ARC PF00931.17 KLO13560.1 - 0.15 10.9 0.1 0.16 10.7 0.0 1.4 1 1 0 1 1 1 0 NB-ARC domain G_glu_transpept PF01019.16 KLO13562.1 - 3.7e-123 411.7 0.0 1.8e-86 290.6 0.0 2.0 1 1 1 2 2 2 2 Gamma-glutamyltranspeptidase WD40 PF00400.27 KLO13563.1 - 4.7e-22 77.0 16.9 2.3e-09 36.7 0.0 4.8 4 1 0 4 4 4 3 WD domain, G-beta repeat AAA_16 PF13191.1 KLO13563.1 - 2.8e-05 24.1 0.1 0.00013 22.0 0.1 2.1 1 1 0 1 1 1 1 AAA ATPase domain NACHT PF05729.7 KLO13563.1 - 3.4e-05 23.5 3.9 0.00032 20.3 2.7 2.3 1 1 0 1 1 1 1 NACHT domain Tox-PL PF15644.1 KLO13563.1 - 0.0026 18.4 0.0 0.0063 17.2 0.0 1.6 1 0 0 1 1 1 1 Papain fold toxin 1 AAA PF00004.24 KLO13563.1 - 0.0038 17.4 0.0 0.033 14.3 0.0 2.6 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) PD40 PF07676.7 KLO13563.1 - 0.063 12.9 0.1 27 4.5 0.0 3.1 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat AAA_22 PF13401.1 KLO13563.1 - 0.11 12.6 0.0 0.5 10.5 0.0 2.1 1 1 0 1 1 1 0 AAA domain PQQ_3 PF13570.1 KLO13563.1 - 0.17 12.2 3.4 7.6 6.9 0.0 3.4 2 1 1 3 3 3 0 PQQ-like domain OppC_N PF12911.2 KLO13564.1 - 1.3 8.4 8.3 5.2 6.5 0.0 2.9 3 0 0 3 3 3 0 N-terminal TM domain of oligopeptide transport permease C F-box-like PF12937.2 KLO13566.1 - 1.7e-06 27.6 0.0 5.3e-06 26.0 0.0 2.0 1 0 0 1 1 1 1 F-box-like BTB PF00651.26 KLO13570.1 - 0.0019 18.1 0.0 0.0034 17.3 0.0 1.4 1 1 0 1 1 1 1 BTB/POZ domain Synthase_beta PF11421.3 KLO13571.1 - 0.0075 16.9 4.6 0.0075 16.9 3.2 3.0 3 1 1 4 4 4 1 ATP synthase F1 beta subunit Med12 PF09497.5 KLO13572.1 - 3.2e-24 84.6 0.0 7.7e-24 83.4 0.0 1.7 1 0 0 1 1 1 1 Transcription mediator complex subunit Med12 Med12-LCEWAV PF12145.3 KLO13572.1 - 0.004 15.6 0.1 0.023 13.2 0.0 2.0 1 1 0 1 1 1 1 Eukaryotic Mediator 12 subunit domain DUF3730 PF12530.3 KLO13572.1 - 0.0054 16.6 0.3 0.019 14.8 0.1 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF3730) BTB PF00651.26 KLO13574.1 - 0.02 14.8 0.1 0.25 11.3 0.0 2.4 2 0 0 2 2 2 0 BTB/POZ domain BTB PF00651.26 KLO13575.1 - 0.038 13.9 0.1 0.1 12.6 0.1 1.8 1 1 0 1 1 1 0 BTB/POZ domain BTB PF00651.26 KLO13576.1 - 0.002 18.1 0.0 0.0076 16.2 0.0 2.1 2 0 0 2 2 2 1 BTB/POZ domain BTB PF00651.26 KLO13577.1 - 0.00078 19.4 0.0 0.0014 18.5 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain p450 PF00067.17 KLO13578.1 - 2.5e-66 224.1 0.0 3.1e-66 223.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 BTB PF00651.26 KLO13579.1 - 0.0017 18.3 0.0 0.0048 16.8 0.0 1.7 1 1 0 1 1 1 1 BTB/POZ domain BTB PF00651.26 KLO13580.1 - 5.5e-06 26.3 0.1 1.6e-05 24.8 0.0 1.8 2 0 0 2 2 2 1 BTB/POZ domain BTB PF00651.26 KLO13581.1 - 0.056 13.4 0.0 0.14 12.1 0.0 1.7 1 1 0 1 1 1 0 BTB/POZ domain BTB PF00651.26 KLO13582.1 - 0.0004 20.3 0.0 0.001 19.0 0.0 1.7 1 1 0 1 1 1 1 BTB/POZ domain BTB PF00651.26 KLO13583.1 - 0.0035 17.2 0.0 0.0094 15.9 0.0 1.7 1 0 0 1 1 1 1 BTB/POZ domain TFIIS_C PF01096.13 KLO13583.1 - 0.073 12.7 0.1 0.17 11.5 0.0 1.7 1 0 0 1 1 1 0 Transcription factor S-II (TFIIS) BTB PF00651.26 KLO13584.1 - 0.04 13.9 0.0 0.092 12.7 0.0 1.7 1 1 0 1 1 1 0 BTB/POZ domain BTB PF00651.26 KLO13585.1 - 4.3e-05 23.4 0.0 8.5e-05 22.5 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain ABM PF03992.11 KLO13586.1 - 0.0049 16.8 0.5 0.051 13.6 0.0 2.4 2 1 0 2 2 2 1 Antibiotic biosynthesis monooxygenase ACPS PF01648.15 KLO13588.1 - 0.0017 18.1 0.0 0.0033 17.2 0.0 1.5 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily Methyltransf_23 PF13489.1 KLO13589.1 - 1.3e-14 54.2 0.0 1.8e-14 53.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KLO13589.1 - 8.4e-12 45.4 0.0 1.5e-11 44.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KLO13589.1 - 5.4e-11 42.3 0.0 1.6e-10 40.7 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KLO13589.1 - 5.2e-09 35.5 0.0 1.8e-08 33.7 0.0 1.8 1 1 1 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.7 KLO13589.1 - 5.2e-06 26.8 0.0 1.2e-05 25.6 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KLO13589.1 - 0.00011 22.5 0.0 0.0003 21.0 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KLO13589.1 - 0.00017 22.1 0.0 0.00055 20.5 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KLO13589.1 - 0.00089 19.2 0.0 0.0024 17.9 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.10 KLO13589.1 - 0.0014 18.3 0.0 0.002 17.7 0.0 1.2 1 0 0 1 1 1 1 Hypothetical methyltransferase APH PF01636.18 KLO13591.1 - 0.024 14.3 0.0 0.033 13.9 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Methyltransf_23 PF13489.1 KLO13593.1 - 1.2e-09 38.0 0.0 1.7e-09 37.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KLO13593.1 - 1.8e-09 37.9 0.0 3e-09 37.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KLO13593.1 - 9.3e-09 35.0 0.0 7.6e-08 32.0 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KLO13593.1 - 6.9e-08 31.8 0.0 2e-07 30.3 0.0 1.6 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.1 KLO13593.1 - 2.1e-05 24.8 0.0 5.7e-05 23.4 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KLO13593.1 - 5.3e-05 23.2 0.0 0.0001 22.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KLO13593.1 - 0.00011 22.6 0.0 0.00029 21.2 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KLO13593.1 - 0.0098 16.4 0.0 0.1 13.1 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.10 KLO13593.1 - 0.082 12.5 0.0 0.11 12.1 0.0 1.2 1 0 0 1 1 1 0 Hypothetical methyltransferase Ubie_methyltran PF01209.13 KLO13594.1 - 2.9e-10 39.6 0.0 1.4e-09 37.4 0.0 2.0 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.1 KLO13594.1 - 6.8e-09 35.6 0.0 8.9e-09 35.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KLO13594.1 - 1e-08 35.5 0.0 1.7e-08 34.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KLO13594.1 - 1.1e-08 34.8 0.0 2.2e-07 30.5 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KLO13594.1 - 4.8e-06 26.8 0.0 1.7e-05 25.0 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KLO13594.1 - 9.1e-05 22.8 0.0 0.00064 20.1 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KLO13594.1 - 0.012 15.6 0.0 0.051 13.6 0.0 1.9 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_18 PF12847.2 KLO13594.1 - 0.015 15.8 0.0 0.45 11.1 0.0 2.1 1 1 0 1 1 1 0 Methyltransferase domain TPMT PF05724.6 KLO13594.1 - 0.032 13.6 0.0 0.042 13.2 0.0 1.2 1 0 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) ABM PF03992.11 KLO13595.1 - 0.0046 16.9 0.0 0.14 12.1 0.0 2.4 2 1 0 2 2 2 1 Antibiotic biosynthesis monooxygenase Sugar_tr PF00083.19 KLO13596.1 - 1.1e-82 278.0 18.5 1.3e-82 277.8 12.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KLO13596.1 - 1.5e-21 76.4 42.5 2.5e-14 52.7 13.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1228 PF06779.9 KLO13596.1 - 0.00058 19.8 9.2 0.1 12.6 0.4 3.5 3 0 0 3 3 3 2 Protein of unknown function (DUF1228) DUF3472 PF11958.3 KLO13599.1 - 4.7e-45 154.2 7.7 8e-45 153.4 5.3 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3472) DUF1690 PF07956.6 KLO13600.1 - 9.9e-11 41.7 5.8 2e-08 34.3 4.0 2.1 1 1 0 1 1 1 1 Protein of Unknown function (DUF1690) OmpH PF03938.9 KLO13600.1 - 0.022 14.6 0.6 0.033 14.1 0.4 1.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Rootletin PF15035.1 KLO13600.1 - 0.031 14.2 1.0 0.17 11.8 0.7 1.9 1 1 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion Bac_luciferase PF00296.15 KLO13600.1 - 0.052 12.6 1.4 0.066 12.3 1.0 1.1 1 0 0 1 1 1 0 Luciferase-like monooxygenase CHCH PF06747.8 KLO13600.1 - 0.073 13.0 0.0 0.13 12.2 0.0 1.4 1 0 0 1 1 1 0 CHCH domain DUF2823 PF11034.3 KLO13600.1 - 2.7 8.1 6.7 0.43 10.7 1.7 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2823) GATA PF00320.22 KLO13601.1 - 6.3e-26 89.4 18.8 1.6e-15 56.1 2.4 2.5 2 0 0 2 2 2 2 GATA zinc finger DUF1752 PF08550.5 KLO13601.1 - 5.1e-11 41.9 0.5 1e-10 40.9 0.4 1.5 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) RRN7 PF11781.3 KLO13601.1 - 0.024 14.1 0.4 0.024 14.1 0.2 2.2 3 0 0 3 3 3 0 RNA polymerase I-specific transcription initiation factor Rrn7 TF_Zn_Ribbon PF08271.7 KLO13601.1 - 0.15 11.4 6.6 0.16 11.2 0.5 2.6 2 0 0 2 2 2 0 TFIIB zinc-binding Remorin_C PF03763.8 KLO13601.1 - 0.29 10.6 4.3 0.58 9.7 3.0 1.4 1 0 0 1 1 1 0 Remorin, C-terminal region Zn-ribbon_8 PF09723.5 KLO13601.1 - 2.1 8.3 5.8 8.1 6.4 0.3 2.7 2 0 0 2 2 2 0 Zinc ribbon domain eIF-5_eIF-2B PF01873.12 KLO13601.1 - 2.5 7.7 7.1 5.9 6.5 0.3 2.3 2 0 0 2 2 2 0 Domain found in IF2B/IF5 zf-RING_3 PF14369.1 KLO13601.1 - 3.7 7.6 6.2 0.43 10.6 0.6 2.2 2 0 0 2 2 2 0 zinc-finger Dicty_REP PF05086.7 KLO13602.1 - 5 4.7 6.2 7.3 4.2 4.3 1.2 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Hid1 PF12722.2 KLO13602.1 - 9.6 3.7 8.9 13 3.3 6.2 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein E1-E2_ATPase PF00122.15 KLO13604.1 - 6.2e-24 84.3 0.0 6.2e-24 84.3 0.0 2.8 3 0 0 3 3 3 1 E1-E2 ATPase Hydrolase PF00702.21 KLO13604.1 - 3.5e-16 60.2 0.0 3.8e-15 56.8 0.0 2.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 KLO13604.1 - 8.1e-12 45.6 0.1 1.8e-11 44.5 0.0 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 KLO13604.1 - 8.8e-07 28.7 0.0 3.4e-06 26.9 0.0 1.9 2 0 0 2 2 2 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 KLO13604.1 - 0.0015 18.2 0.1 0.0039 16.7 0.1 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase NST1 PF13945.1 KLO13605.1 - 2.6e-54 184.1 0.0 2.6e-54 184.1 0.0 6.1 4 1 1 5 5 5 1 Salt tolerance down-regulator TFIIA PF03153.8 KLO13605.1 - 0.00054 19.9 17.6 0.00054 19.9 12.2 5.5 3 1 2 5 5 5 1 Transcription factor IIA, alpha/beta subunit cEGF PF12662.2 KLO13606.1 - 0.017 14.7 0.1 0.041 13.5 0.1 1.6 1 0 0 1 1 1 0 Complement Clr-like EGF-like PD40 PF07676.7 KLO13608.1 - 0.14 11.8 1.2 2.4 7.9 0.2 3.1 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat BTB PF00651.26 KLO13609.1 - 0.00032 20.6 0.0 0.00076 19.4 0.0 1.6 1 1 0 1 1 1 1 BTB/POZ domain BTB PF00651.26 KLO13611.1 - 2.2e-07 30.8 0.0 9.8e-07 28.7 0.0 2.1 2 0 0 2 2 2 1 BTB/POZ domain BTB PF00651.26 KLO13612.1 - 2.3e-08 33.9 0.1 6.8e-08 32.4 0.0 1.8 2 0 0 2 2 2 1 BTB/POZ domain BTB PF00651.26 KLO13613.1 - 0.0025 17.7 0.0 0.0068 16.3 0.0 1.7 1 1 0 1 1 1 1 BTB/POZ domain Inositol_P PF00459.20 KLO13615.1 - 1.6e-54 185.0 0.1 7.1e-54 182.9 0.0 1.7 1 1 0 1 1 1 1 Inositol monophosphatase family MFS_1 PF07690.11 KLO13616.1 - 7.6e-28 97.2 22.9 5.3e-25 87.8 18.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF4083 PF13314.1 KLO13616.1 - 0.13 12.0 0.0 0.66 9.8 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4083) Peptidase_S9 PF00326.16 KLO13617.1 - 7.4e-31 107.0 0.0 1.3e-30 106.2 0.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 KLO13617.1 - 7.4e-10 38.7 0.0 1.4e-09 37.8 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KLO13617.1 - 6.8e-09 35.9 0.0 1.2e-08 35.1 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family BAAT_C PF08840.6 KLO13617.1 - 0.00018 21.2 0.0 0.00031 20.4 0.0 1.3 1 0 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_1 PF00561.15 KLO13617.1 - 0.00042 19.9 0.1 0.34 10.4 0.0 3.0 2 1 1 3 3 3 2 alpha/beta hydrolase fold DLH PF01738.13 KLO13617.1 - 0.00058 19.2 0.0 0.001 18.4 0.0 1.4 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_3 PF07859.8 KLO13617.1 - 0.0031 17.1 0.0 0.0059 16.2 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_2 PF02230.11 KLO13617.1 - 0.033 13.6 0.0 0.056 12.8 0.0 1.3 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase FSH1 PF03959.8 KLO13617.1 - 0.1 12.0 0.0 0.21 11.0 0.0 1.4 1 0 0 1 1 1 0 Serine hydrolase (FSH1) PAM2 PF07145.10 KLO13618.1 - 2.1 8.0 6.8 0.54 9.8 2.0 2.1 2 0 0 2 2 2 0 Ataxin-2 C-terminal region Mito_fiss_reg PF05308.6 KLO13619.1 - 0.12 11.7 1.4 0.26 10.6 1.0 1.6 1 0 0 1 1 1 0 Mitochondrial fission regulator DUF1294 PF06961.8 KLO13620.1 - 0.15 12.0 0.1 0.24 11.3 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1294) DDE_3 PF13358.1 KLO13622.1 - 2e-08 34.0 0.0 3.5e-08 33.3 0.0 1.4 2 0 0 2 2 2 1 DDE superfamily endonuclease DDE_3 PF13358.1 KLO13623.1 - 7.8e-15 54.8 0.0 2.4e-14 53.2 0.0 1.7 1 1 0 1 1 1 1 DDE superfamily endonuclease DUF4150 PF13665.1 KLO13624.1 - 0.12 12.2 1.1 5.9 6.8 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4150) Macoilin PF09726.4 KLO13625.1 - 0.62 8.2 10.1 0.7 8.1 7.0 1.1 1 0 0 1 1 1 0 Transmembrane protein TMEM171 PF15471.1 KLO13625.1 - 0.7 8.6 4.2 1.1 8.0 2.8 1.4 1 1 0 1 1 1 0 Transmembrane protein family 171 DUF605 PF04652.11 KLO13625.1 - 2.7 7.3 19.1 3.7 6.8 13.3 1.3 1 0 0 1 1 1 0 Vta1 like NAD_kinase PF01513.16 KLO13626.1 - 1.6e-58 197.7 0.0 2.2e-58 197.2 0.0 1.1 1 0 0 1 1 1 1 ATP-NAD kinase UPF0560 PF10577.4 KLO13628.1 - 0.073 11.3 0.0 0.099 10.8 0.0 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 RNA_polI_A14 PF08203.6 KLO13628.1 - 0.24 11.6 1.0 0.45 10.7 0.7 1.4 1 0 0 1 1 1 0 Yeast RNA polymerase I subunit RPA14 LCAT PF02450.10 KLO13629.1 - 3.8e-79 266.4 0.8 1.5e-78 264.5 0.6 1.9 1 1 0 1 1 1 1 Lecithin:cholesterol acyltransferase Abhydrolase_6 PF12697.2 KLO13629.1 - 2.8e-05 24.0 0.4 6.3e-05 22.9 0.0 1.8 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KLO13629.1 - 9.3e-05 22.2 0.1 0.00018 21.2 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF900 PF05990.7 KLO13629.1 - 0.0048 16.2 0.0 0.0078 15.5 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF900) Lipase_2 PF01674.13 KLO13629.1 - 0.076 12.3 0.0 0.15 11.3 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 2) FGase PF05013.7 KLO13629.1 - 0.084 12.7 0.0 0.14 12.0 0.0 1.2 1 0 0 1 1 1 0 N-formylglutamate amidohydrolase PGAP1 PF07819.8 KLO13629.1 - 0.11 12.0 0.0 0.22 11.0 0.0 1.5 1 0 0 1 1 1 0 PGAP1-like protein RRM_1 PF00076.17 KLO13630.1 - 3.1e-05 23.5 0.0 7.6e-05 22.2 0.0 1.7 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KLO13630.1 - 0.0096 15.8 0.0 0.02 14.8 0.0 1.6 1 1 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) F-box PF00646.28 KLO13631.1 - 0.025 14.2 0.7 0.13 11.9 0.0 2.6 3 0 0 3 3 3 0 F-box domain PspB PF06667.7 KLO13631.1 - 0.039 13.8 0.2 0.11 12.4 0.1 1.8 2 0 0 2 2 2 0 Phage shock protein B F-box-like PF12937.2 KLO13631.1 - 0.043 13.5 0.0 0.14 11.9 0.0 1.9 1 0 0 1 1 1 0 F-box-like Glucosamine_iso PF01182.15 KLO13633.1 - 7.1e-26 91.1 0.0 1.1e-25 90.5 0.0 1.2 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase IGPS PF00218.16 KLO13634.1 - 2e-87 292.4 0.0 4e-87 291.4 0.0 1.5 2 0 0 2 2 2 1 Indole-3-glycerol phosphate synthase PRAI PF00697.17 KLO13634.1 - 1.2e-52 178.3 0.0 9e-46 155.9 0.0 2.3 2 0 0 2 2 2 2 N-(5'phosphoribosyl)anthranilate (PRA) isomerase GATase PF00117.23 KLO13634.1 - 2e-47 161.1 0.0 3.7e-47 160.2 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.8 KLO13634.1 - 7.4e-08 32.0 0.1 2e-07 30.6 0.0 1.7 2 0 0 2 2 2 1 Peptidase C26 QRPTase_C PF01729.14 KLO13634.1 - 1.6e-05 24.5 0.1 0.0051 16.3 0.1 3.7 4 0 0 4 4 4 1 Quinolinate phosphoribosyl transferase, C-terminal domain FMN_dh PF01070.13 KLO13634.1 - 0.00053 18.9 0.8 0.0055 15.5 0.2 2.4 2 1 1 3 3 3 1 FMN-dependent dehydrogenase PcrB PF01884.12 KLO13634.1 - 0.18 11.0 0.5 7.6 5.7 0.0 2.6 1 1 1 2 2 2 0 PcrB family Pkinase PF00069.20 KLO13635.1 - 1.8e-68 230.5 0.0 2.2e-68 230.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KLO13635.1 - 2.7e-28 98.7 0.0 3.8e-28 98.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 KLO13635.1 - 0.012 14.6 0.0 0.021 13.8 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KLO13635.1 - 0.017 14.8 0.2 0.045 13.4 0.1 1.7 1 1 1 2 2 2 0 Phosphotransferase enzyme family Isochorismatase PF00857.15 KLO13636.1 - 3.3e-22 79.2 0.1 1.2e-21 77.4 0.0 1.8 1 1 0 1 1 1 1 Isochorismatase family Tetraspannin PF00335.15 KLO13638.1 - 2e-05 23.9 15.5 4.1e-05 22.9 10.7 1.6 1 1 0 1 1 1 1 Tetraspanin family DUF2975 PF11188.3 KLO13638.1 - 0.81 9.4 12.6 1 9.0 7.2 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF2975) SUR7 PF06687.7 KLO13638.1 - 0.93 9.0 17.6 0.11 12.0 6.5 2.2 1 1 1 2 2 2 0 SUR7/PalI family DUF2254 PF10011.4 KLO13638.1 - 1.6 7.1 5.8 1.2 7.5 2.2 1.9 2 0 0 2 2 2 0 Predicted membrane protein (DUF2254) Tetraspannin PF00335.15 KLO13639.1 - 1.2e-09 37.8 3.1 1.6e-09 37.4 2.1 1.2 1 0 0 1 1 1 1 Tetraspanin family ABC2_membrane_4 PF12730.2 KLO13639.1 - 0.61 9.2 14.8 0.43 9.6 9.4 1.4 1 1 0 1 1 1 0 ABC-2 family transporter protein DUF2970 PF11174.3 KLO13639.1 - 3.2 7.4 6.0 0.92 9.1 0.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF2970) Cation_ATPase_C PF00689.16 KLO13639.1 - 5.7 6.4 8.6 0.76 9.2 2.9 1.8 2 1 0 2 2 2 0 Cation transporting ATPase, C-terminus AtpR PF12966.2 KLO13639.1 - 6.9 6.8 10.2 24 5.1 5.7 2.4 1 1 1 2 2 2 0 N-ATPase, AtpR subunit p450 PF00067.17 KLO13640.1 - 5e-61 206.6 0.0 4.7e-60 203.4 0.0 2.2 1 1 0 1 1 1 1 Cytochrome P450 zf-MYND PF01753.13 KLO13641.1 - 1.1e-07 31.5 15.7 2.7e-07 30.3 10.9 1.7 1 0 0 1 1 1 1 MYND finger DUF3846 PF12957.2 KLO13641.1 - 0.066 12.9 0.0 0.15 11.7 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3846) zf-Mss51 PF13824.1 KLO13641.1 - 4.5 7.2 9.1 16 5.4 6.3 1.9 1 1 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 FGE-sulfatase PF03781.11 KLO13644.1 - 4e-18 65.7 1.9 4.9e-16 58.8 1.3 2.1 1 1 0 1 1 1 1 Sulfatase-modifying factor enzyme 1 DinB_2 PF12867.2 KLO13644.1 - 1.5e-10 41.5 1.6 3.5e-10 40.3 1.1 1.6 1 0 0 1 1 1 1 DinB superfamily FMN_dh PF01070.13 KLO13646.1 - 1.5e-119 399.0 0.0 1.9e-119 398.6 0.0 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.23 KLO13646.1 - 5.1e-24 83.8 0.0 1.4e-23 82.4 0.0 1.8 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain IMPDH PF00478.20 KLO13646.1 - 0.00026 20.0 0.0 0.00043 19.2 0.0 1.3 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.12 KLO13646.1 - 0.0003 19.8 0.0 0.00049 19.1 0.0 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase PI-PLC-X PF00388.14 KLO13647.1 - 1.4e-08 34.2 0.0 3.2e-08 33.0 0.0 1.5 1 1 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain Acetyltransf_1 PF00583.19 KLO13648.1 - 1.9e-07 31.0 0.0 3.4e-07 30.1 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family GNAT_acetyltr_2 PF13718.1 KLO13648.1 - 0.0068 15.7 0.0 0.01 15.2 0.0 1.2 1 0 0 1 1 1 1 GNAT acetyltransferase 2 Acetyltransf_13 PF13880.1 KLO13648.1 - 0.0096 15.6 0.0 0.02 14.6 0.0 1.5 1 0 0 1 1 1 1 ESCO1/2 acetyl-transferase Acetyltransf_7 PF13508.1 KLO13648.1 - 0.012 15.7 0.0 0.026 14.6 0.0 1.5 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 KLO13648.1 - 0.034 14.2 0.0 0.07 13.2 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 KLO13648.1 - 0.035 13.9 0.0 0.058 13.2 0.0 1.3 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Acetyltransf_9 PF13527.1 KLO13648.1 - 0.15 11.9 0.0 0.52 10.1 0.0 1.9 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain DPBB_1 PF03330.13 KLO13652.1 - 3.5e-05 23.7 0.1 0.00016 21.6 0.0 2.1 2 1 0 2 2 2 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Barwin PF00967.12 KLO13652.1 - 0.0047 16.6 0.0 0.0067 16.0 0.0 1.2 1 0 0 1 1 1 1 Barwin family Abhydrolase_3 PF07859.8 KLO13653.1 - 1e-39 136.3 0.3 4e-34 118.0 0.0 3.1 3 0 0 3 3 3 2 alpha/beta hydrolase fold DUF2424 PF10340.4 KLO13653.1 - 6.2e-10 38.2 0.0 1.3e-09 37.1 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2424) Abhydrolase_5 PF12695.2 KLO13653.1 - 4.8e-06 26.3 0.0 9.4e-06 25.4 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family COesterase PF00135.23 KLO13653.1 - 0.0035 16.1 0.3 0.036 12.7 0.0 2.2 2 0 0 2 2 2 1 Carboxylesterase family Trypan_PARP PF05887.6 KLO13654.1 - 0.0031 17.3 55.5 0.11 12.3 20.4 2.4 1 1 1 2 2 2 2 Procyclic acidic repetitive protein (PARP) Pkinase PF00069.20 KLO13656.1 - 6.2e-59 199.2 0.0 7.7e-59 198.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KLO13656.1 - 5.5e-30 104.2 0.0 7.1e-30 103.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KLO13656.1 - 2.7e-05 23.2 0.0 4.8e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 KLO13656.1 - 0.00091 19.0 0.0 0.0085 15.8 0.0 2.1 2 0 0 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.17 KLO13656.1 - 0.074 12.4 0.0 2.4 7.4 0.0 2.1 2 0 0 2 2 2 0 RIO1 family DUF1658 PF07871.6 KLO13658.1 - 0.057 13.0 1.7 0.76 9.4 0.1 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF1658) tRNA-synt_2b PF00587.20 KLO13660.1 - 6.6e-43 146.2 0.0 1e-42 145.6 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 KLO13660.1 - 7.8e-19 67.4 0.1 1.8e-18 66.2 0.1 1.7 1 0 0 1 1 1 1 Anticodon binding domain TGS PF02824.16 KLO13660.1 - 9.4e-11 41.3 0.0 2e-10 40.3 0.0 1.6 1 0 0 1 1 1 1 TGS domain tRNA_SAD PF07973.9 KLO13660.1 - 6.8e-09 35.4 0.0 1.6e-08 34.2 0.0 1.7 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain Foie-gras_1 PF11817.3 KLO13661.1 - 1.2e-41 142.8 0.0 5.8e-41 140.6 0.0 2.2 2 1 0 2 2 2 1 Foie gras liver health family 1 Gryzun PF07919.7 KLO13661.1 - 6.6e-36 123.7 0.1 3.9e-19 68.4 0.1 2.7 3 0 0 3 3 3 2 Gryzun, putative trafficking through Golgi TPR_12 PF13424.1 KLO13661.1 - 0.031 14.2 0.0 2.4 8.1 0.0 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.12 KLO13661.1 - 0.27 11.2 2.0 0.52 10.3 0.0 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat SAE2 PF08573.5 KLO13662.1 - 3.2e-14 53.3 1.1 3.2e-14 53.3 0.8 3.3 3 1 0 3 3 3 1 DNA repair protein endonuclease SAE2/CtIP C-terminus p450 PF00067.17 KLO13664.1 - 2.2e-41 141.8 0.0 7.9e-29 100.4 0.0 2.9 1 1 1 2 2 2 2 Cytochrome P450 SUR7 PF06687.7 KLO13665.1 - 3.9e-18 65.7 19.5 6.6e-18 65.0 13.5 1.4 1 1 0 1 1 1 1 SUR7/PalI family Prominin PF05478.6 KLO13665.1 - 0.14 9.7 1.2 0.34 8.3 0.0 1.9 2 0 0 2 2 2 0 Prominin DUF975 PF06161.6 KLO13665.1 - 0.18 11.5 16.5 0.056 13.1 6.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF975) DUF4014 PF13198.1 KLO13665.1 - 3.4 8.1 5.6 13 6.2 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF4014) HflK_N PF12221.3 KLO13666.1 - 0.12 12.0 0.0 0.21 11.3 0.0 1.3 1 0 0 1 1 1 0 Bacterial membrane protein N terminal PMP1_2 PF08114.6 KLO13667.1 - 0.17 11.3 0.4 0.49 9.9 0.0 1.8 2 0 0 2 2 2 0 ATPase proteolipid family GH114_assoc PF14741.1 KLO13668.1 - 0.07 12.8 0.1 0.083 12.6 0.1 1.1 1 0 0 1 1 1 0 N-terminal glycosyl-hydrolase-114-associated domain Pyocin_S PF06958.7 KLO13669.1 - 0.018 15.4 0.3 0.041 14.2 0.2 1.6 1 0 0 1 1 1 0 S-type Pyocin ubiquitin PF00240.18 KLO13671.1 - 3.3e-07 29.6 0.4 4.4e-07 29.2 0.3 1.2 1 0 0 1 1 1 1 Ubiquitin family Ubiquitin_2 PF14560.1 KLO13671.1 - 1.2e-05 25.4 0.6 2.2e-05 24.6 0.4 1.4 1 1 0 1 1 1 1 Ubiquitin-like domain Rad60-SLD PF11976.3 KLO13671.1 - 0.011 15.4 0.6 0.018 14.6 0.4 1.4 1 1 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like UN_NPL4 PF11543.3 KLO13671.1 - 0.022 15.0 0.0 0.023 14.9 0.0 1.1 1 0 0 1 1 1 0 Nuclear pore localisation protein NPL4 G-patch PF01585.18 KLO13673.1 - 4.3e-06 26.4 0.8 1.3e-05 24.8 0.2 2.2 2 0 0 2 2 2 1 G-patch domain G-patch_2 PF12656.2 KLO13673.1 - 2e-05 24.3 0.2 2e-05 24.3 0.2 4.6 4 1 1 5 5 5 1 DExH-box splicing factor binding site MIP-T3 PF10243.4 KLO13673.1 - 0.00067 18.2 13.1 0.00067 18.2 9.1 2.1 2 0 0 2 2 2 1 Microtubule-binding protein MIP-T3 TrkH PF02386.11 KLO13675.1 - 7.8e-88 294.4 16.1 2e-87 293.0 6.0 2.1 2 0 0 2 2 2 2 Cation transport protein Vps54 PF07928.7 KLO13675.1 - 0.16 12.1 0.8 1 9.5 0.0 2.1 2 0 0 2 2 2 0 Vps54-like protein AAA_12 PF13087.1 KLO13676.1 - 6.5e-16 58.3 0.0 1.5e-15 57.1 0.0 1.6 1 1 0 1 1 1 1 AAA domain UvrD_C_2 PF13538.1 KLO13676.1 - 8.9e-07 29.0 0.0 2.2e-06 27.7 0.0 1.7 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain Cas_Cas4 PF01930.12 KLO13677.1 - 0.0074 16.2 0.7 0.024 14.5 0.0 2.1 2 0 0 2 2 2 1 Domain of unknown function DUF83 LCM PF04072.9 KLO13678.1 - 1.8e-22 79.8 0.0 3e-22 79.0 0.0 1.4 1 0 0 1 1 1 1 Leucine carboxyl methyltransferase Tim17 PF02466.14 KLO13679.1 - 4.9e-33 113.9 8.3 6.5e-33 113.5 5.7 1.1 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family DUF543 PF04418.7 KLO13679.1 - 0.056 13.4 0.6 0.37 10.7 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF543) FMN_dh PF01070.13 KLO13680.1 - 4.1e-121 404.1 0.0 5e-121 403.8 0.0 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.23 KLO13680.1 - 1.7e-22 78.9 0.0 4.4e-22 77.6 0.0 1.8 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Glu_synthase PF01645.12 KLO13680.1 - 1.8e-05 23.8 0.0 3e-05 23.1 0.0 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.20 KLO13680.1 - 3.1e-05 23.0 0.0 6.6e-05 21.9 0.0 1.5 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain DHO_dh PF01180.16 KLO13680.1 - 0.046 12.6 0.1 0.11 11.4 0.0 1.6 2 0 0 2 2 2 0 Dihydroorotate dehydrogenase NMO PF03060.10 KLO13680.1 - 0.07 12.2 0.2 0.12 11.4 0.1 1.3 1 0 0 1 1 1 0 Nitronate monooxygenase ThiG PF05690.9 KLO13680.1 - 0.073 12.1 0.0 4.1 6.4 0.0 2.2 2 0 0 2 2 2 0 Thiazole biosynthesis protein ThiG His_biosynth PF00977.16 KLO13680.1 - 0.094 11.9 0.1 0.28 10.4 0.0 1.7 1 1 0 2 2 2 0 Histidine biosynthesis protein F-box-like PF12937.2 KLO13681.1 - 1.4e-07 31.0 0.4 1.7e-06 27.6 0.0 2.6 2 0 0 2 2 2 1 F-box-like F-box-like PF12937.2 KLO13682.1 - 1.2e-07 31.3 0.1 3.7e-06 26.5 0.0 2.8 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 KLO13682.1 - 0.0037 16.8 0.5 0.018 14.7 0.0 2.5 3 0 0 3 3 3 1 F-box domain Cellulase PF00150.13 KLO13684.1 - 6.2e-13 48.5 0.0 1.2e-12 47.6 0.0 1.4 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) RRM_1 PF00076.17 KLO13686.1 - 2.1e-35 120.1 0.0 3.3e-20 71.5 0.0 3.6 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KLO13686.1 - 5.3e-18 64.7 0.1 7.2e-12 45.1 0.0 3.6 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KLO13686.1 - 7.4e-12 44.9 0.0 1.5e-05 24.7 0.0 3.6 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM PF05172.8 KLO13686.1 - 0.022 14.4 0.0 0.062 13.0 0.0 1.7 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif Limkain-b1 PF11608.3 KLO13686.1 - 0.059 13.1 0.1 4.7 7.0 0.0 2.6 2 0 0 2 2 2 0 Limkain b1 Nup35_RRM_2 PF14605.1 KLO13686.1 - 0.069 12.9 0.0 0.74 9.6 0.0 2.2 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif PABP PF00658.13 KLO13686.1 - 0.096 12.3 0.6 16 5.2 0.3 2.7 2 0 0 2 2 2 0 Poly-adenylate binding protein, unique domain GCN5L1 PF06320.8 KLO13688.1 - 0.049 13.4 0.1 0.086 12.6 0.0 1.3 1 0 0 1 1 1 0 GCN5-like protein 1 (GCN5L1) zf-MYND PF01753.13 KLO13690.1 - 3.3e-08 33.2 8.9 6.9e-08 32.2 6.2 1.6 1 0 0 1 1 1 1 MYND finger zf-MYND PF01753.13 KLO13691.1 - 1.6e-09 37.5 7.6 2.9e-09 36.6 5.3 1.5 1 0 0 1 1 1 1 MYND finger zf-Mss51 PF13824.1 KLO13691.1 - 0.51 10.2 6.7 5.1 7.0 4.7 2.5 1 1 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 NTF2 PF02136.15 KLO13692.1 - 3.6e-27 95.0 0.0 5.7e-27 94.4 0.0 1.3 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain RRM_1 PF00076.17 KLO13692.1 - 6.3e-07 28.9 0.0 1.1e-06 28.2 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KLO13692.1 - 0.0001 22.2 0.0 0.00016 21.5 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KLO13692.1 - 0.0019 17.9 0.0 0.0034 17.2 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 KLO13692.1 - 0.04 13.7 0.0 0.097 12.5 0.0 1.6 1 0 0 1 1 1 0 RNA binding motif Hydrophobin PF01185.13 KLO13693.1 - 1.8e-12 47.5 3.1 2.3e-12 47.1 2.1 1.1 1 0 0 1 1 1 1 Fungal hydrophobin Hydrophobin PF01185.13 KLO13694.1 - 6e-12 45.8 2.2 7.3e-12 45.5 1.5 1.1 1 0 0 1 1 1 1 Fungal hydrophobin F-box-like PF12937.2 KLO13695.1 - 2.9e-10 39.7 0.6 2.9e-10 39.7 0.4 1.7 2 0 0 2 2 2 1 F-box-like Epimerase PF01370.16 KLO13697.1 - 6.3e-07 29.0 0.0 1.9e-06 27.4 0.0 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 KLO13697.1 - 0.00085 19.3 0.5 0.0017 18.4 0.3 1.6 1 1 0 1 1 1 1 NADH(P)-binding Saccharop_dh PF03435.13 KLO13697.1 - 0.002 17.1 0.1 0.0034 16.4 0.1 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase Semialdhyde_dh PF01118.19 KLO13697.1 - 0.0049 17.1 0.0 0.0094 16.2 0.0 1.5 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain NmrA PF05368.8 KLO13697.1 - 0.0057 15.9 0.0 0.012 14.9 0.0 1.5 1 0 0 1 1 1 1 NmrA-like family TrkA_N PF02254.13 KLO13697.1 - 0.0083 16.1 0.0 0.023 14.7 0.0 1.7 2 0 0 2 2 2 1 TrkA-N domain MFS_1 PF07690.11 KLO13698.1 - 2.5e-28 98.8 35.9 2.5e-28 98.8 24.9 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily Zip PF02535.17 KLO13698.1 - 3.3 6.6 7.4 0.5 9.3 0.3 2.4 2 0 0 2 2 2 0 ZIP Zinc transporter zf-MYND PF01753.13 KLO13699.1 - 5.6e-10 38.9 6.9 9.3e-10 38.2 4.8 1.4 1 0 0 1 1 1 1 MYND finger SH3_1 PF00018.23 KLO13700.1 - 1.6e-30 104.2 0.2 4e-10 38.9 0.0 3.4 3 0 0 3 3 3 3 SH3 domain SH3_2 PF07653.12 KLO13700.1 - 4.7e-23 80.4 0.0 5.6e-07 28.9 0.0 3.4 3 0 0 3 3 3 3 Variant SH3 domain SH3_9 PF14604.1 KLO13700.1 - 1.2e-18 66.4 0.2 7.2e-06 25.4 0.0 3.4 3 0 0 3 3 3 3 Variant SH3 domain zf-MYND PF01753.13 KLO13702.1 - 1.8e-09 37.3 8.5 2.9e-09 36.6 5.9 1.4 1 0 0 1 1 1 1 MYND finger Pkinase PF00069.20 KLO13704.1 - 4.2e-68 229.3 0.0 5e-68 229.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KLO13704.1 - 7.1e-27 94.1 0.0 1e-26 93.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KLO13704.1 - 9.7e-07 28.0 0.0 1.5e-06 27.4 0.0 1.2 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.17 KLO13704.1 - 0.0032 16.8 0.0 0.0056 16.0 0.0 1.4 1 0 0 1 1 1 1 RIO1 family APH PF01636.18 KLO13704.1 - 0.0062 16.3 0.3 0.37 10.4 0.1 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.9 KLO13704.1 - 0.0077 15.3 0.3 0.016 14.3 0.2 1.4 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family TcdB_toxin_midN PF12256.3 KLO13704.1 - 0.054 12.9 0.0 0.092 12.1 0.0 1.4 1 0 0 1 1 1 0 Insecticide toxin TcdB middle/N-terminal region YukC PF10140.4 KLO13704.1 - 0.06 11.9 0.0 0.08 11.4 0.0 1.1 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukC Mad3_BUB1_I PF08311.7 KLO13705.1 - 1.1e-26 93.0 0.1 1.6e-26 92.5 0.0 1.2 1 0 0 1 1 1 1 Mad3/BUB1 homology region 1 Pkinase PF00069.20 KLO13706.1 - 7.9e-74 248.0 0.0 9.6e-74 247.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KLO13706.1 - 9.3e-31 106.8 0.0 2.6e-30 105.3 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KLO13706.1 - 0.00036 19.5 0.0 0.00056 18.9 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 KLO13706.1 - 0.0069 15.4 0.1 0.012 14.6 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KLO13706.1 - 0.035 13.8 0.6 0.42 10.2 0.1 1.9 1 1 1 2 2 2 0 Phosphotransferase enzyme family YukC PF10140.4 KLO13706.1 - 0.059 11.9 0.0 0.075 11.5 0.0 1.2 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukC Seadorna_VP7 PF07387.6 KLO13706.1 - 0.098 11.4 0.0 0.15 10.8 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 BCDHK_Adom3 PF10436.4 KLO13707.1 - 1.7e-64 216.2 0.0 2.3e-64 215.8 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.21 KLO13707.1 - 1.6e-19 69.6 0.0 3.6e-19 68.5 0.0 1.6 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.1 KLO13707.1 - 0.0001 21.9 0.0 0.00019 21.0 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF3446 PF11928.3 KLO13708.1 - 3 8.1 5.9 7.6 6.7 0.9 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3446) Ribosomal_L16 PF00252.13 KLO13709.1 - 3.6e-33 114.1 0.1 4.5e-33 113.8 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e CBF PF03914.12 KLO13713.1 - 6.2e-40 136.3 1.1 6.2e-40 136.3 0.8 2.4 2 1 2 4 4 4 1 CBF/Mak21 family HEAT PF02985.17 KLO13713.1 - 0.029 14.4 0.5 1.1 9.5 0.0 3.4 3 0 0 3 3 3 0 HEAT repeat Hexapep PF00132.19 KLO13714.1 - 1.1e-10 40.4 16.3 0.00013 21.3 0.2 3.8 2 2 1 3 3 3 3 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.1 KLO13714.1 - 0.0038 16.7 9.8 0.074 12.6 0.0 3.1 2 1 1 3 3 3 3 Hexapeptide repeat of succinyl-transferase CAP_GLY PF01302.20 KLO13715.1 - 2.7e-09 36.5 0.9 3.2e-08 33.1 0.5 2.4 2 0 0 2 2 2 1 CAP-Gly domain BTB PF00651.26 KLO13715.1 - 3.1e-09 36.8 0.0 1.8e-08 34.3 0.0 2.2 3 0 0 3 3 3 1 BTB/POZ domain zf-CCCH PF00642.19 KLO13716.1 - 0.00015 21.3 7.1 0.0013 18.3 1.1 2.3 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.1 KLO13716.1 - 0.64 10.1 11.1 0.21 11.6 1.7 2.5 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type PAS_9 PF13426.1 KLO13717.1 - 5.1e-26 91.0 0.0 2.7e-16 59.8 0.0 3.8 3 1 0 3 3 3 3 PAS domain PAS PF00989.19 KLO13717.1 - 3e-16 59.1 0.0 6.3e-05 22.7 0.0 4.2 4 0 0 4 4 4 3 PAS fold PAS_3 PF08447.6 KLO13717.1 - 7.9e-12 45.1 0.0 0.0021 18.1 0.0 4.5 4 0 0 4 4 4 3 PAS fold PAS_4 PF08448.5 KLO13717.1 - 1.8e-10 40.8 0.0 0.0021 18.0 0.0 3.6 3 0 0 3 3 3 2 PAS fold PAS_11 PF14598.1 KLO13717.1 - 6.1e-09 35.8 0.0 0.027 14.3 0.0 3.4 3 0 0 3 3 3 3 PAS domain PAS_8 PF13188.1 KLO13717.1 - 0.018 14.8 0.0 0.61 10.0 0.0 2.7 2 0 0 2 2 2 0 PAS domain EIF_2_alpha PF07541.7 KLO13718.1 - 1.7e-28 98.6 0.0 5.2e-28 97.0 0.0 1.9 2 0 0 2 2 2 1 Eukaryotic translation initiation factor 2 alpha subunit S1 PF00575.18 KLO13718.1 - 7.6e-14 51.5 1.4 1.3e-13 50.8 1.0 1.4 1 0 0 1 1 1 1 S1 RNA binding domain EXOSC1 PF10447.4 KLO13718.1 - 0.047 13.6 0.4 0.15 11.9 0.3 2.0 1 1 0 1 1 1 0 Exosome component EXOSC1/CSL4 Kinesin PF00225.18 KLO13719.1 - 3e-89 299.0 0.2 4.8e-89 298.3 0.0 1.4 2 0 0 2 2 2 1 Kinesin motor domain DUF3186 PF11382.3 KLO13719.1 - 0.11 11.6 6.5 1.4 7.9 0.1 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF3186) TPR_2 PF07719.12 KLO13719.1 - 0.13 12.2 0.1 0.13 12.2 0.1 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat zf-UDP PF14569.1 KLO13719.1 - 1.6 8.5 5.7 13 5.6 0.2 2.6 2 0 0 2 2 2 0 Zinc-binding RING-finger Cytochrom_B561 PF03188.11 KLO13720.1 - 6.1e-10 39.0 7.9 3.5e-09 36.6 5.3 1.9 2 0 0 2 2 2 1 Eukaryotic cytochrome b561 DUF4181 PF13789.1 KLO13720.1 - 0.013 15.4 0.4 0.013 15.4 0.3 2.6 2 1 1 3 3 3 0 Domain of unknown function (DUF4181) DUF2427 PF10348.4 KLO13720.1 - 0.017 14.7 2.4 0.017 14.7 1.6 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF2427) DUF1469 PF07332.6 KLO13720.1 - 0.021 14.5 0.2 0.021 14.5 0.1 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF1469) PRA1 PF03208.14 KLO13720.1 - 3.5 6.9 8.8 2.5 7.4 0.6 2.5 2 1 0 2 2 2 0 PRA1 family protein Ku PF02735.11 KLO13721.1 - 0.15 11.4 0.0 0.21 10.9 0.0 1.2 1 0 0 1 1 1 0 Ku70/Ku80 beta-barrel domain MR_MLE_C PF13378.1 KLO13722.1 - 6.6e-16 58.2 0.1 1.4e-15 57.1 0.0 1.6 1 0 0 1 1 1 1 Enolase C-terminal domain-like MR_MLE PF01188.16 KLO13722.1 - 1.3e-12 48.0 0.1 4e-12 46.4 0.0 1.9 2 0 0 2 2 2 1 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain MR_MLE_N PF02746.11 KLO13722.1 - 3.5e-07 30.2 0.0 8.5e-07 28.9 0.0 1.6 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain MAAL_C PF07476.6 KLO13722.1 - 0.073 11.9 0.0 0.12 11.3 0.0 1.2 1 0 0 1 1 1 0 Methylaspartate ammonia-lyase C-terminus Cauli_VI PF01693.11 KLO13724.1 - 1e-11 44.6 0.0 2e-11 43.7 0.0 1.4 1 0 0 1 1 1 1 Caulimovirus viroplasmin DnaJ PF00226.26 KLO13725.1 - 7.5e-23 80.0 0.1 6.1e-22 77.1 0.0 2.4 2 0 0 2 2 2 1 DnaJ domain Selenoprotein_S PF06936.6 KLO13725.1 - 2.7 7.4 10.4 6.3 6.2 7.2 1.6 1 0 0 1 1 1 0 Selenoprotein S (SelS) tRNA-synt_2 PF00152.15 KLO13726.1 - 1.3e-73 247.6 0.0 2e-73 247.0 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 KLO13726.1 - 1.7e-06 27.8 0.0 4e-06 26.5 0.0 1.6 2 0 0 2 2 2 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.15 KLO13726.1 - 0.0037 16.4 0.1 1.9 7.6 0.0 2.5 2 1 0 2 2 2 2 tRNA synthetases class II core domain (F) tRNA-synt_2b PF00587.20 KLO13726.1 - 0.025 14.1 0.0 0.63 9.6 0.0 2.3 2 0 0 2 2 2 0 tRNA synthetase class II core domain (G, H, P, S and T) WD40 PF00400.27 KLO13727.1 - 7e-39 130.3 16.2 2.1e-12 46.3 0.1 6.7 6 0 0 6 6 6 6 WD domain, G-beta repeat eIF2A PF08662.6 KLO13727.1 - 1.3e-06 28.2 0.0 0.049 13.3 0.0 2.4 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A Nucleoporin_N PF08801.6 KLO13727.1 - 2.1e-06 26.7 0.2 0.00011 21.1 0.0 2.7 1 1 1 3 3 3 1 Nup133 N terminal like Cytochrom_D1 PF02239.11 KLO13727.1 - 0.0012 17.2 0.0 0.74 8.0 0.0 3.1 3 0 0 3 3 3 2 Cytochrome D1 heme domain Nbas_N PF15492.1 KLO13727.1 - 0.0097 15.0 0.1 1.8 7.5 0.0 2.4 1 1 1 2 2 2 2 Neuroblastoma-amplified sequence, N terminal Pkinase PF00069.20 KLO13728.1 - 9.2e-33 113.4 0.0 1.2e-32 113.1 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KLO13728.1 - 1.8e-28 99.3 0.0 2.3e-28 98.9 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 KLO13728.1 - 0.017 14.8 0.0 0.023 14.4 0.0 1.1 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kinase-like PF14531.1 KLO13728.1 - 0.03 13.2 0.0 0.045 12.7 0.0 1.1 1 0 0 1 1 1 0 Kinase-like RIO1 PF01163.17 KLO13728.1 - 0.11 11.7 0.0 0.17 11.1 0.0 1.2 1 0 0 1 1 1 0 RIO1 family Pkinase_Tyr PF07714.12 KLO13729.1 - 3.6e-68 229.4 0.0 2.1e-40 138.4 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.20 KLO13729.1 - 1.3e-64 217.8 0.0 2.4e-43 148.1 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Kinase-like PF14531.1 KLO13729.1 - 2.1e-08 33.4 0.0 0.0023 16.9 0.0 2.5 2 1 0 2 2 2 2 Kinase-like RIO1 PF01163.17 KLO13729.1 - 0.00082 18.7 1.0 0.85 8.9 0.0 3.2 3 0 0 3 3 3 2 RIO1 family ABC1 PF03109.11 KLO13729.1 - 0.085 12.8 0.0 0.23 11.4 0.0 1.7 1 0 0 1 1 1 0 ABC1 family zf-MYND PF01753.13 KLO13730.1 - 3.7e-08 33.1 14.1 3.7e-08 33.1 9.8 2.2 2 0 0 2 2 2 1 MYND finger zf-Mss51 PF13824.1 KLO13730.1 - 0.071 12.9 4.6 0.18 11.7 3.2 1.6 1 0 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 PBP-Tp47_a PF14889.1 KLO13730.1 - 0.14 11.4 0.0 0.26 10.6 0.0 1.3 1 0 0 1 1 1 0 Penicillin-binding protein Tp47 domain a zf-MYND PF01753.13 KLO13731.1 - 9.3e-08 31.8 15.8 1.6e-07 31.0 11.0 1.4 1 0 0 1 1 1 1 MYND finger zf-MYND PF01753.13 KLO13732.1 - 2.4e-09 36.9 14.0 4e-09 36.2 9.7 1.4 1 0 0 1 1 1 1 MYND finger zf-Mss51 PF13824.1 KLO13732.1 - 0.58 10.0 4.2 1.2 9.0 2.9 1.5 1 0 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 zf-MYND PF01753.13 KLO13733.1 - 9.2e-09 35.0 14.0 2.4e-08 33.7 9.7 1.8 1 0 0 1 1 1 1 MYND finger zf-Mss51 PF13824.1 KLO13733.1 - 0.77 9.6 4.5 2.1 8.2 3.1 1.7 1 0 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 DEAD PF00270.24 KLO13734.1 - 0.00086 18.8 0.0 0.0012 18.4 0.0 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase zf-MYND PF01753.13 KLO13735.1 - 2.2e-08 33.8 16.2 2.2e-08 33.8 11.3 2.2 2 0 0 2 2 2 1 MYND finger PolC_DP2 PF03833.8 KLO13735.1 - 0.59 7.7 4.9 1 6.9 3.4 1.3 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 Peptidase_C13 PF01650.13 KLO13737.1 - 1.7e-42 145.5 0.3 2.1e-42 145.1 0.2 1.1 1 0 0 1 1 1 1 Peptidase C13 family WD40 PF00400.27 KLO13738.1 - 1.9e-65 214.5 13.0 2.1e-11 43.2 0.0 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat Tup_N PF08581.5 KLO13738.1 - 4.3e-21 74.8 6.9 9.4e-21 73.8 4.8 1.6 1 0 0 1 1 1 1 Tup N-terminal Cytochrom_D1 PF02239.11 KLO13738.1 - 0.00014 20.2 1.0 0.0041 15.4 0.0 2.8 2 1 0 3 3 3 1 Cytochrome D1 heme domain Nucleoporin_N PF08801.6 KLO13738.1 - 0.00083 18.2 0.1 2.6 6.7 0.0 3.7 2 1 1 3 3 3 2 Nup133 N terminal like IncA PF04156.9 KLO13738.1 - 0.0038 16.8 2.9 0.0038 16.8 2.0 1.5 2 0 0 2 2 1 1 IncA protein PD40 PF07676.7 KLO13738.1 - 0.0067 16.0 0.0 26 4.6 0.0 4.8 5 0 0 5 5 5 0 WD40-like Beta Propeller Repeat Nbas_N PF15492.1 KLO13738.1 - 0.011 14.8 0.1 7.8 5.5 0.0 3.2 2 1 1 4 4 4 0 Neuroblastoma-amplified sequence, N terminal Nup160 PF11715.3 KLO13738.1 - 0.019 13.1 0.3 0.71 7.9 0.1 3.0 1 1 2 3 3 3 0 Nucleoporin Nup120/160 PSII_BNR PF14870.1 KLO13738.1 - 0.051 12.5 0.1 0.088 11.7 0.0 1.3 1 0 0 1 1 1 0 Photosynthesis system II assembly factor YCF48 DDHD PF02862.12 KLO13738.1 - 0.059 13.1 0.0 0.097 12.4 0.0 1.2 1 0 0 1 1 1 0 DDHD domain Apis_Csd PF11671.3 KLO13738.1 - 10 5.9 10.7 20 4.9 7.4 1.4 1 0 0 1 1 1 0 Complementary sex determiner protein F-box-like PF12937.2 KLO13739.1 - 5.5e-09 35.6 0.2 3e-08 33.2 0.0 2.3 2 0 0 2 2 2 1 F-box-like F-box-like PF12937.2 KLO13740.1 - 3.4e-06 26.6 0.0 8.1e-06 25.4 0.0 1.7 1 0 0 1 1 1 1 F-box-like Lectin_leg-like PF03388.8 KLO13741.1 - 5.2e-65 218.7 0.1 6.8e-65 218.4 0.0 1.1 1 0 0 1 1 1 1 Legume-like lectin family Lectin_legB PF00139.14 KLO13741.1 - 0.03 13.6 0.0 3.1 7.0 0.0 2.3 2 0 0 2 2 2 0 Legume lectin domain zf-DNL PF05180.7 KLO13742.1 - 3.6e-26 90.6 0.4 5.2e-26 90.1 0.3 1.2 1 0 0 1 1 1 1 DNL zinc finger zf-MYND PF01753.13 KLO13743.1 - 4.7e-09 35.9 14.2 1.1e-08 34.7 9.9 1.7 1 0 0 1 1 1 1 MYND finger zf-MYND PF01753.13 KLO13744.1 - 3.3e-09 36.4 12.9 6.3e-09 35.5 8.9 1.5 1 0 0 1 1 1 1 MYND finger zf-MYND PF01753.13 KLO13745.1 - 5.1e-09 35.8 12.3 8.8e-09 35.1 8.5 1.4 1 0 0 1 1 1 1 MYND finger PBP-Tp47_a PF14889.1 KLO13745.1 - 0.016 14.5 0.0 0.029 13.6 0.0 1.3 1 0 0 1 1 1 0 Penicillin-binding protein Tp47 domain a zf-MYND PF01753.13 KLO13746.1 - 4.3e-07 29.6 16.1 7.9e-07 28.8 11.2 1.4 1 0 0 1 1 1 1 MYND finger Ecl1 PF12855.2 KLO13746.1 - 0.28 10.5 5.6 0.58 9.4 3.9 1.5 1 0 0 1 1 1 0 Life-span regulatory factor zf-MYND PF01753.13 KLO13747.1 - 1.5e-06 27.9 18.8 2.5e-06 27.2 13.1 1.4 1 0 0 1 1 1 1 MYND finger zf-Mss51 PF13824.1 KLO13747.1 - 0.013 15.3 6.5 0.032 14.0 4.1 2.0 2 0 0 2 2 2 0 Zinc-finger of mitochondrial splicing suppressor 51 Prok-RING_2 PF14445.1 KLO13747.1 - 0.14 12.1 9.6 0.2 11.6 4.3 2.7 3 0 0 3 3 3 0 Prokaryotic RING finger family 2 zf-MYND PF01753.13 KLO13748.1 - 7.3e-07 28.9 17.5 1.2e-06 28.2 12.2 1.3 1 0 0 1 1 1 1 MYND finger zf-MYND PF01753.13 KLO13749.1 - 2.3e-06 27.3 15.6 4e-06 26.5 10.8 1.4 1 0 0 1 1 1 1 MYND finger zf-MYND PF01753.13 KLO13750.1 - 6.3e-06 25.9 12.9 1e-05 25.3 9.0 1.3 1 0 0 1 1 1 1 MYND finger Ribosomal_L37e PF01907.14 KLO13750.1 - 0.0041 16.8 5.1 0.14 12.0 3.2 2.3 2 0 0 2 2 2 1 Ribosomal protein L37e FYVE PF01363.16 KLO13750.1 - 0.096 12.5 6.0 0.17 11.8 4.2 1.3 1 0 0 1 1 1 0 FYVE zinc finger Prok-RING_2 PF14445.1 KLO13750.1 - 0.24 11.3 4.5 0.66 9.9 2.3 2.1 2 0 0 2 2 2 0 Prokaryotic RING finger family 2 zf-Mss51 PF13824.1 KLO13750.1 - 0.32 10.8 3.9 0.66 9.8 2.7 1.5 1 0 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 zf-ribbon_3 PF13248.1 KLO13750.1 - 0.63 9.3 3.2 1.2 8.4 2.2 1.4 1 0 0 1 1 1 0 zinc-ribbon domain zf-MYND PF01753.13 KLO13751.1 - 1.7e-05 24.5 18.1 2.8e-05 23.8 12.5 1.4 1 0 0 1 1 1 1 MYND finger zf-Mss51 PF13824.1 KLO13751.1 - 8.4 6.3 8.3 24 4.8 5.7 1.8 1 1 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 Glyco_transf_22 PF03901.12 KLO13752.1 - 7e-81 272.3 13.5 1.2e-80 271.6 9.4 1.4 1 1 0 1 1 1 1 Alg9-like mannosyltransferase family DUF423 PF04241.10 KLO13755.1 - 1.5e-18 66.4 2.4 1.5e-18 66.4 1.7 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF423) SdpI PF13630.1 KLO13755.1 - 1.8 8.3 5.0 0.86 9.3 0.2 2.6 2 2 0 2 2 2 0 SdpI/YhfL protein family DUF1741 PF08427.5 KLO13756.1 - 1.7e-41 142.2 0.0 1.7e-41 142.2 0.0 2.0 3 0 0 3 3 3 1 Domain of unknown function (DUF1741) Rota_NS6 PF04866.7 KLO13756.1 - 0.096 12.7 1.1 0.57 10.2 0.0 2.7 3 0 0 3 3 3 0 Rotavirus non-structural protein 6 GDC-P PF02347.11 KLO13758.1 - 2e-185 616.5 0.0 2.7e-173 576.5 0.0 2.9 3 0 0 3 3 3 2 Glycine cleavage system P-protein Beta_elim_lyase PF01212.16 KLO13758.1 - 0.0033 16.5 0.0 0.0063 15.6 0.0 1.4 1 0 0 1 1 1 1 Beta-eliminating lyase PPR_2 PF13041.1 KLO13759.1 - 3.8e-16 58.8 0.2 0.16 11.9 0.0 8.5 8 1 1 9 9 9 4 PPR repeat family PPR_3 PF13812.1 KLO13759.1 - 6.3e-10 38.5 1.9 0.048 13.9 0.1 6.9 7 0 0 7 7 7 2 Pentatricopeptide repeat domain PPR PF01535.15 KLO13759.1 - 2.6e-06 27.0 13.4 0.62 10.1 0.0 8.5 8 1 0 8 8 8 2 PPR repeat PPR_1 PF12854.2 KLO13759.1 - 1e-05 24.8 0.6 0.15 11.5 0.0 6.0 7 0 0 7 7 7 1 PPR repeat Med2 PF11214.3 KLO13759.1 - 0.0021 18.0 4.8 0.01 15.8 3.3 2.2 1 1 0 1 1 1 1 Mediator complex subunit 2 Sec8_exocyst PF04048.9 KLO13759.1 - 0.037 13.6 8.1 0.74 9.4 3.4 2.7 2 0 0 2 2 2 0 Sec8 exocyst complex component specific domain IF-2B PF01008.12 KLO13759.1 - 0.063 12.2 5.2 0.14 11.1 3.6 1.5 1 0 0 1 1 1 0 Initiation factor 2 subunit family Seryl_tRNA_N PF02403.17 KLO13759.1 - 0.92 9.5 11.1 0.11 12.5 3.8 2.4 2 1 1 3 3 3 0 Seryl-tRNA synthetase N-terminal domain DUF3099 PF11298.3 KLO13760.1 - 0.9 9.3 3.2 8 6.2 0.1 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3099) NAD_binding_4 PF07993.7 KLO13762.1 - 7e-34 116.8 0.0 1.1e-33 116.2 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.23 KLO13762.1 - 2.2e-31 108.6 0.0 3.2e-31 108.1 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme Epimerase PF01370.16 KLO13762.1 - 3.8e-11 42.8 0.0 7.3e-11 41.9 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.20 KLO13762.1 - 0.00088 19.4 0.0 0.0025 18.0 0.0 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site 3Beta_HSD PF01073.14 KLO13762.1 - 0.002 16.9 0.0 0.0066 15.1 0.0 1.7 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.20 KLO13762.1 - 0.005 16.7 0.1 0.022 14.6 0.1 2.1 1 1 0 1 1 1 1 short chain dehydrogenase NAD_binding_10 PF13460.1 KLO13762.1 - 0.047 13.6 0.0 0.74 9.7 0.0 2.8 2 1 0 2 2 2 0 NADH(P)-binding KR PF08659.5 KLO13762.1 - 0.074 12.7 0.0 0.19 11.3 0.0 1.7 1 1 0 1 1 1 0 KR domain Semialdhyde_dh PF01118.19 KLO13762.1 - 0.075 13.3 0.0 0.16 12.2 0.0 1.5 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain NAD_binding_4 PF07993.7 KLO13764.1 - 3.3e-36 124.4 0.0 5.1e-36 123.8 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.23 KLO13764.1 - 1.1e-30 106.4 0.0 2.2e-30 105.4 0.0 1.5 1 1 0 1 1 1 1 AMP-binding enzyme Epimerase PF01370.16 KLO13764.1 - 7e-11 42.0 0.0 1.5e-10 40.9 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 KLO13764.1 - 0.00014 20.7 0.0 0.00029 19.6 0.0 1.4 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family PP-binding PF00550.20 KLO13764.1 - 0.00076 19.6 0.0 0.0023 18.1 0.0 1.9 1 0 0 1 1 1 1 Phosphopantetheine attachment site adh_short PF00106.20 KLO13764.1 - 0.023 14.6 0.1 0.16 11.9 0.0 2.3 1 1 0 1 1 1 0 short chain dehydrogenase KR PF08659.5 KLO13764.1 - 0.1 12.2 0.0 0.27 10.8 0.0 1.8 1 1 0 1 1 1 0 KR domain TraS PF10624.4 KLO13765.1 - 0.34 10.4 4.4 0.81 9.2 3.1 1.6 1 0 0 1 1 1 0 Plasmid conjugative transfer entry exclusion protein TraS Oxidored_q2 PF00420.19 KLO13765.1 - 1.3 8.6 7.7 0.21 11.2 2.1 2.2 1 1 1 2 2 2 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L zf-C3HC4_3 PF13920.1 KLO13769.1 - 8.1e-11 41.4 5.5 1.7e-10 40.4 3.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KLO13769.1 - 6.1e-10 38.9 8.5 1.3e-09 37.9 5.9 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KLO13769.1 - 1.7e-08 34.1 6.7 3.2e-08 33.2 4.7 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 KLO13769.1 - 2.2e-07 30.4 8.2 5e-07 29.2 5.7 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KLO13769.1 - 5.4e-07 29.2 7.7 1.2e-06 28.0 5.3 1.6 1 0 0 1 1 1 1 zinc-RING finger domain SUR7 PF06687.7 KLO13769.1 - 1.7e-05 24.4 4.1 3.7e-05 23.3 0.0 2.1 1 1 1 2 2 2 1 SUR7/PalI family zf-C3HC4_4 PF15227.1 KLO13769.1 - 0.0028 17.5 8.5 0.0064 16.3 5.9 1.7 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.1 KLO13769.1 - 0.0042 16.5 4.6 0.0099 15.4 3.2 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-rbx1 PF12678.2 KLO13769.1 - 0.0043 17.1 3.5 0.011 15.7 2.4 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_UBOX PF13445.1 KLO13769.1 - 0.044 13.4 6.2 0.097 12.4 4.3 1.6 1 0 0 1 1 1 0 RING-type zinc-finger zf-RING_4 PF14570.1 KLO13769.1 - 0.055 13.0 7.4 0.17 11.5 5.1 1.7 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Amastin PF07344.6 KLO13769.1 - 0.067 12.7 1.2 0.14 11.7 0.9 1.7 1 1 0 1 1 1 0 Amastin surface glycoprotein DUF3353 PF11833.3 KLO13769.1 - 0.087 12.2 0.3 0.087 12.2 0.2 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3353) DUF1517 PF07466.6 KLO13770.1 - 0.033 13.1 0.2 0.057 12.3 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1517) Abhydrolase_9_N PF15420.1 KLO13771.1 - 0.7 9.6 6.4 2.9 7.5 1.1 2.3 2 0 0 2 2 2 0 Alpha/beta-hydrolase family N-terminus PepSY_TM_2 PF13703.1 KLO13771.1 - 7.9 6.7 10.0 0.19 11.9 0.5 2.6 2 1 0 2 2 2 0 PepSY-associated TM helix DUF1218 PF06749.7 KLO13773.1 - 0.00071 19.9 3.4 0.64 10.5 0.0 2.3 2 1 0 2 2 2 2 Protein of unknown function (DUF1218) DUF21 PF01595.15 KLO13773.1 - 0.28 10.4 4.7 0.076 12.2 1.3 1.5 2 0 0 2 2 2 0 Domain of unknown function DUF21 DUF4181 PF13789.1 KLO13774.1 - 9.9 6.1 12.8 1.4 8.8 0.3 3.4 3 1 0 3 3 3 0 Domain of unknown function (DUF4181) AA_permease PF00324.16 KLO13776.1 - 1.9e-119 399.1 35.2 2.3e-119 398.8 24.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 KLO13776.1 - 1.2e-32 112.9 39.1 1.5e-32 112.6 27.1 1.0 1 0 0 1 1 1 1 Amino acid permease IlvB_leader PF08049.6 KLO13776.1 - 1.2 8.9 3.1 0.93 9.2 0.8 1.9 2 0 0 2 2 2 0 IlvB leader peptide Zn_clus PF00172.13 KLO13777.1 - 3e-05 23.8 11.1 4.5e-05 23.2 7.7 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pkinase PF00069.20 KLO13780.1 - 5.8e-08 32.2 0.1 9.9e-07 28.1 0.0 2.2 2 0 0 2 2 2 1 Protein kinase domain Zn_clus PF00172.13 KLO13780.1 - 0.0046 16.8 8.1 0.0046 16.8 5.6 2.4 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.11 KLO13781.1 - 3.6e-36 124.6 19.4 4.9e-36 124.1 13.4 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_1_like PF12832.2 KLO13781.1 - 0.015 15.1 0.5 0.06 13.1 0.1 2.2 2 0 0 2 2 2 0 MFS_1 like family DUF1180 PF06679.7 KLO13781.1 - 0.13 12.1 0.0 0.42 10.4 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) PgaD PF13994.1 KLO13781.1 - 2.1 7.7 6.1 17 4.8 0.0 3.7 3 1 2 5 5 5 0 PgaD-like protein DUF4231 PF14015.1 KLO13781.1 - 2.6 8.0 9.1 2.8 7.9 0.3 3.6 1 1 3 4 4 4 0 Protein of unknown function (DUF4231) Ipi1_N PF12333.3 KLO13784.1 - 6.5e-14 51.7 5.3 1.2e-11 44.4 1.0 4.6 2 1 2 4 4 4 1 Rix1 complex component involved in 60S ribosome maturation Cnd1 PF12717.2 KLO13784.1 - 0.00022 21.1 0.1 0.00044 20.1 0.1 1.4 1 0 0 1 1 1 1 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.15 KLO13784.1 - 0.015 13.6 0.2 0.026 12.8 0.1 1.3 1 0 0 1 1 1 0 Adaptin N terminal region HEAT PF02985.17 KLO13784.1 - 0.11 12.6 0.0 29 5.0 0.0 3.8 3 0 0 3 3 3 0 HEAT repeat RhoGEF PF00621.15 KLO13786.1 - 2e-42 145.0 0.0 4.3e-42 144.0 0.0 1.6 2 0 0 2 2 2 1 RhoGEF domain LRR_4 PF12799.2 KLO13786.1 - 1.5e-10 40.4 19.0 9.7e-05 21.8 0.8 3.3 1 1 3 4 4 4 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KLO13786.1 - 1.7e-09 37.2 9.6 3e-05 23.6 0.4 3.1 2 1 1 3 3 3 2 Leucine rich repeat LRR_7 PF13504.1 KLO13786.1 - 0.0068 16.4 1.1 6 7.5 0.1 3.9 3 0 0 3 3 3 1 Leucine rich repeat LRR_1 PF00560.28 KLO13786.1 - 0.024 14.5 6.9 1.5 9.1 0.2 4.2 4 0 0 4 4 4 0 Leucine Rich Repeat LRR_6 PF13516.1 KLO13786.1 - 0.16 12.1 0.6 1.4 9.2 0.1 2.9 2 0 0 2 2 2 0 Leucine Rich repeat zf-RING_5 PF14634.1 KLO13787.1 - 5.5e-06 25.9 3.2 1.4e-05 24.7 2.2 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.20 KLO13787.1 - 3.3e-05 23.4 2.5 9.6e-05 21.9 1.7 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KLO13787.1 - 5.9e-05 22.8 2.4 0.00016 21.4 1.7 1.7 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 KLO13787.1 - 0.00038 20.0 2.0 0.00092 18.8 1.4 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KLO13787.1 - 0.00043 20.2 1.6 0.00043 20.2 1.1 2.0 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) SUR7 PF06687.7 KLO13787.1 - 0.00056 19.5 6.3 0.002 17.7 4.7 1.7 1 1 0 1 1 1 1 SUR7/PalI family zf-C3HC4_4 PF15227.1 KLO13787.1 - 0.038 13.8 2.1 0.083 12.7 0.3 2.3 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 KLO13787.1 - 0.1 12.3 2.2 0.2 11.3 1.5 1.5 1 0 0 1 1 1 0 RING-type zinc-finger F-box-like PF12937.2 KLO13788.1 - 1.7e-06 27.6 1.5 1.7e-06 27.6 1.0 2.0 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 KLO13788.1 - 4.1e-06 26.3 5.1 9.9e-06 25.0 3.6 1.7 1 0 0 1 1 1 1 F-box domain F-box PF00646.28 KLO13790.1 - 4.2e-05 23.0 2.4 8.8e-05 22.0 1.7 1.6 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 KLO13790.1 - 0.0015 18.2 0.4 0.0033 17.1 0.2 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KLO13791.1 - 2.9e-06 26.7 4.5 2.9e-06 26.7 3.2 2.0 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.2 KLO13791.1 - 2.6e-05 23.8 1.0 8.4e-05 22.2 0.7 1.9 1 0 0 1 1 1 1 F-box-like F-box-like_2 PF13013.1 KLO13791.1 - 0.012 15.3 1.2 0.02 14.6 0.2 1.8 2 0 0 2 2 2 0 F-box-like domain F-box PF00646.28 KLO13792.1 - 3.5e-07 29.7 3.6 6.6e-07 28.8 2.5 1.5 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 KLO13792.1 - 0.0037 16.9 0.8 0.012 15.3 0.7 1.8 2 0 0 2 2 2 1 F-box-like Glyco_transf_8 PF01501.15 KLO13793.1 - 1.8e-25 89.6 0.0 3.6e-25 88.7 0.0 1.4 1 1 0 1 1 1 1 Glycosyl transferase family 8 HET PF06985.6 KLO13795.1 - 7.3e-07 29.4 0.2 0.001 19.2 0.0 2.7 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) Pkinase PF00069.20 KLO13796.1 - 1.3e-07 31.0 0.3 2.7e-06 26.7 0.0 2.3 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 KLO13796.1 - 0.052 12.6 0.0 0.19 10.7 0.0 1.8 2 0 0 2 2 2 0 Protein tyrosine kinase BSP_II PF05432.6 KLO13796.1 - 0.056 12.7 5.9 0.097 11.9 4.1 1.3 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) Nucleoplasmin PF03066.10 KLO13796.1 - 1.1 8.7 9.9 2.9 7.4 6.8 1.7 1 0 0 1 1 1 0 Nucleoplasmin CENP-B_dimeris PF09026.5 KLO13796.1 - 6.9 6.9 12.0 18 5.6 8.3 1.6 1 0 0 1 1 1 0 Centromere protein B dimerisation domain BTB PF00651.26 KLO13797.1 - 1.2e-05 25.2 0.0 2.2e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain IBR PF01485.16 KLO13798.1 - 1.4e-11 44.0 23.2 8.2e-06 25.6 2.8 2.4 1 1 1 2 2 2 2 IBR domain UPF0547 PF10571.4 KLO13798.1 - 0.67 9.6 19.8 0.1 12.3 5.5 3.7 3 1 0 3 3 3 0 Uncharacterised protein family UPF0547 SH3_1 PF00018.23 KLO13799.1 - 1.6e-11 43.3 0.1 3e-11 42.5 0.1 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 KLO13799.1 - 4.7e-10 38.8 0.0 8.5e-10 38.0 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 KLO13799.1 - 2.5e-06 26.8 0.0 4.8e-06 25.9 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain CytochromB561_N PF09786.4 KLO13804.1 - 0.25 9.7 4.1 0.25 9.7 2.2 1.5 1 1 0 1 1 1 0 Cytochrome B561, N terminal DUF443 PF04276.7 KLO13804.1 - 0.45 9.9 13.2 0.41 10.0 7.3 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF443) zf-UBR PF02207.15 KLO13805.1 - 0.04 13.6 2.9 0.065 12.9 2.0 1.5 1 0 0 1 1 1 0 Putative zinc finger in N-recognin (UBR box) DUF4614 PF15391.1 KLO13805.1 - 0.076 12.7 2.8 0.088 12.5 2.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4614) Stc1 PF12898.2 KLO13805.1 - 0.078 13.0 4.6 0.12 12.4 3.2 1.4 1 0 0 1 1 1 0 Stc1 domain zf-H2C2_2 PF13465.1 KLO13805.1 - 0.14 12.5 2.9 0.14 12.5 0.1 2.2 2 0 0 2 2 2 0 Zinc-finger double domain DZR PF12773.2 KLO13805.1 - 0.88 9.4 5.3 1.4 8.7 3.7 1.5 1 1 0 1 1 1 0 Double zinc ribbon zf-HIT PF04438.11 KLO13805.1 - 1.4 8.6 11.0 1.2 8.8 0.2 2.6 3 0 0 3 3 3 0 HIT zinc finger Zn_Tnp_IS1595 PF12760.2 KLO13805.1 - 6.5 6.6 6.6 0.51 10.1 0.4 2.2 3 0 0 3 3 3 0 Transposase zinc-ribbon domain APH PF01636.18 KLO13806.1 - 4.2e-14 52.8 0.1 1.5e-12 47.7 0.1 2.2 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 KLO13806.1 - 1.9e-09 37.4 0.0 3.7e-09 36.4 0.0 1.4 1 1 0 1 1 1 1 Choline/ethanolamine kinase RIO1 PF01163.17 KLO13806.1 - 0.015 14.6 0.3 0.11 11.8 0.0 2.2 2 0 0 2 2 2 0 RIO1 family CBM_19 PF03427.8 KLO13807.1 - 0.017 14.8 0.9 0.017 14.8 0.6 2.0 2 0 0 2 2 2 0 Carbohydrate binding domain (family 19) Beta-lactamase PF00144.19 KLO13808.1 - 7.6e-44 150.0 0.0 1.6e-43 148.9 0.0 1.5 1 1 0 1 1 1 1 Beta-lactamase DUF3471 PF11954.3 KLO13808.1 - 0.00029 20.6 0.0 0.00075 19.2 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF3471) Beta-lactamase PF00144.19 KLO13809.1 - 7.9e-30 103.9 0.2 1.4e-29 103.2 0.1 1.3 1 0 0 1 1 1 1 Beta-lactamase DUF3471 PF11954.3 KLO13809.1 - 0.023 14.5 0.1 0.061 13.1 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3471) p450 PF00067.17 KLO13810.1 - 8.6e-67 225.6 0.0 2.3e-66 224.2 0.0 1.5 1 1 0 1 1 1 1 Cytochrome P450 F-box-like PF12937.2 KLO13811.1 - 9.1e-10 38.1 0.7 2e-09 36.9 0.5 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KLO13811.1 - 9.2e-05 21.9 0.5 0.0011 18.6 0.3 2.4 1 1 0 1 1 1 1 F-box domain Methyltransf_23 PF13489.1 KLO13812.1 - 6.1e-11 42.2 0.0 1.1e-10 41.4 0.0 1.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KLO13812.1 - 2.9e-10 40.4 0.0 4.1e-10 40.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KLO13812.1 - 5.4e-10 39.0 0.0 1.7e-09 37.4 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KLO13812.1 - 2.6e-06 27.9 0.0 1.1e-05 26.0 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KLO13812.1 - 9.9e-06 25.9 0.0 1.6e-05 25.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KLO13812.1 - 1.1e-05 25.7 0.0 2.1e-05 24.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KLO13812.1 - 0.0023 17.9 0.0 0.017 15.1 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain MetW PF07021.7 KLO13812.1 - 0.0028 17.0 0.0 0.0055 16.0 0.0 1.4 1 1 0 1 1 1 1 Methionine biosynthesis protein MetW FtsJ PF01728.14 KLO13812.1 - 0.0081 16.1 0.0 0.009 16.0 0.0 1.2 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_4 PF02390.12 KLO13812.1 - 0.026 13.5 0.0 0.11 11.5 0.0 1.8 2 0 0 2 2 2 0 Putative methyltransferase Ubie_methyltran PF01209.13 KLO13812.1 - 0.042 12.9 0.0 1.4 8.0 0.0 2.8 2 1 0 2 2 2 0 ubiE/COQ5 methyltransferase family Abhydrolase_6 PF12697.2 KLO13813.1 - 5.2e-20 72.3 0.0 6.2e-20 72.0 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KLO13813.1 - 0.00044 20.0 0.0 0.00076 19.2 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family HSP70 PF00012.15 KLO13814.1 - 0.0054 14.6 0.1 0.0099 13.8 0.1 1.3 1 0 0 1 1 1 1 Hsp70 protein MFS_1 PF07690.11 KLO13815.1 - 1.6e-33 115.9 29.8 1.6e-33 115.9 20.6 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily CoA_transf_3 PF02515.12 KLO13815.1 - 0.014 14.6 0.0 0.098 11.8 0.0 2.2 1 1 1 2 2 2 0 CoA-transferase family III Exo_endo_phos PF03372.18 KLO13816.1 - 1.1e-22 81.1 0.0 3.7e-22 79.4 0.0 1.8 2 0 0 2 2 2 1 Endonuclease/Exonuclease/phosphatase family SMC_N PF02463.14 KLO13817.1 - 4e-66 222.3 8.7 7.7e-66 221.4 6.0 1.6 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 KLO13817.1 - 6.2e-28 97.1 0.0 4.7e-27 94.3 0.0 2.7 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.1 KLO13817.1 - 2.9e-14 53.7 2.7 9.5e-07 29.0 0.3 3.0 2 2 0 2 2 2 2 AAA domain AAA_23 PF13476.1 KLO13817.1 - 1.8e-10 41.4 36.7 1.8e-10 41.4 25.4 6.6 2 2 2 4 4 3 1 AAA domain AAA_29 PF13555.1 KLO13817.1 - 0.0017 17.8 0.0 0.004 16.6 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain APG6 PF04111.7 KLO13817.1 - 0.002 17.2 3.8 0.002 17.2 2.7 6.5 2 2 2 6 6 6 2 Autophagy protein Apg6 Reo_sigmaC PF04582.7 KLO13817.1 - 0.0043 16.2 22.8 0.18 10.9 0.2 5.7 2 2 2 6 6 6 3 Reovirus sigma C capsid protein DUF2968 PF11180.3 KLO13817.1 - 0.0064 15.9 3.4 0.0064 15.9 2.4 6.5 4 1 2 6 6 6 1 Protein of unknown function (DUF2968) AAA_13 PF13166.1 KLO13817.1 - 0.073 11.5 84.4 0.32 9.4 6.3 6.2 4 2 2 6 6 6 0 AAA domain IncA PF04156.9 KLO13817.1 - 0.084 12.4 107.1 0.015 14.9 3.4 6.8 3 2 3 6 6 6 0 IncA protein ABC_tran PF00005.22 KLO13817.1 - 0.98 9.7 0.0 0.98 9.7 0.0 5.8 3 2 0 3 3 2 0 ABC transporter AAA_27 PF13514.1 KLO13817.1 - 1.1 6.8 92.0 0.0025 15.6 5.2 4.3 2 2 2 4 4 4 0 AAA domain GAS PF13851.1 KLO13817.1 - 7.9 5.6 100.6 0.009 15.2 3.3 6.9 3 2 4 7 7 6 0 Growth-arrest specific micro-tubule binding F-box-like PF12937.2 KLO13818.1 - 0.00028 20.5 0.0 0.0013 18.4 0.0 2.3 2 1 0 2 2 2 1 F-box-like PPR_2 PF13041.1 KLO13819.1 - 0.00081 19.3 0.0 0.15 12.0 0.0 3.0 2 0 0 2 2 2 2 PPR repeat family MFS_1 PF07690.11 KLO13820.1 - 1.7e-15 56.5 18.4 3.8e-15 55.4 11.7 2.4 1 1 0 1 1 1 1 Major Facilitator Superfamily Nodulin-like PF06813.8 KLO13820.1 - 3.2e-14 52.7 6.7 5.3e-07 29.1 0.1 2.7 3 0 0 3 3 3 2 Nodulin-like Tcf25 PF04910.9 KLO13821.1 - 4.5e-68 229.8 0.0 6e-68 229.4 0.0 1.2 1 0 0 1 1 1 1 Transcriptional repressor TCF25 TPR_12 PF13424.1 KLO13821.1 - 0.004 17.0 0.0 0.011 15.6 0.0 1.8 1 0 0 1 1 1 1 Tetratricopeptide repeat DUF2225 PF09986.4 KLO13821.1 - 0.048 13.1 0.1 0.084 12.3 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2225) TPR_14 PF13428.1 KLO13821.1 - 0.27 11.9 2.8 0.77 10.5 0.1 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat p450 PF00067.17 KLO13822.1 - 4.3e-68 229.9 0.0 5.5e-68 229.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 KLO13823.1 - 1.4e-61 208.4 0.0 4.5e-61 206.7 0.0 1.8 1 1 0 1 1 1 1 Cytochrome P450 Beta-lactamase PF00144.19 KLO13824.1 - 1.4e-45 155.8 0.0 2e-45 155.2 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase DUF3471 PF11954.3 KLO13824.1 - 0.0026 17.5 1.5 0.0085 15.9 0.1 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF3471) p450 PF00067.17 KLO13825.1 - 2.2e-61 207.7 0.0 4.4e-61 206.8 0.0 1.4 1 1 0 1 1 1 1 Cytochrome P450 SNO PF01174.14 KLO13826.1 - 2.4e-47 161.0 0.0 1.3e-45 155.4 0.0 2.0 1 1 0 1 1 1 1 SNO glutamine amidotransferase family GATase_3 PF07685.9 KLO13826.1 - 1.3e-08 34.5 0.0 2.1e-08 33.9 0.0 1.3 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain GATase PF00117.23 KLO13826.1 - 8.5e-05 22.0 0.1 0.0006 19.3 0.0 1.9 2 0 0 2 2 2 1 Glutamine amidotransferase class-I Peptidase_S51 PF03575.12 KLO13826.1 - 0.0002 21.1 0.0 0.0003 20.5 0.0 1.2 1 0 0 1 1 1 1 Peptidase family S51 DUF4066 PF13278.1 KLO13826.1 - 0.003 16.8 0.0 0.0049 16.1 0.0 1.3 1 0 0 1 1 1 1 Putative amidotransferase DJ-1_PfpI PF01965.19 KLO13826.1 - 0.025 14.0 0.0 0.039 13.4 0.0 1.3 1 0 0 1 1 1 0 DJ-1/PfpI family PNP_UDP_1 PF01048.15 KLO13827.1 - 8.7e-35 119.7 0.0 1e-34 119.5 0.0 1.0 1 0 0 1 1 1 1 Phosphorylase superfamily A_thal_3526 PF09713.5 KLO13827.1 - 0.023 14.8 0.2 0.042 13.9 0.1 1.4 1 0 0 1 1 1 0 Plant protein 1589 of unknown function (A_thal_3526) Patatin PF01734.17 KLO13828.1 - 1.1e-19 71.1 0.3 8.1e-19 68.3 0.2 2.1 1 1 0 1 1 1 1 Patatin-like phospholipase p450 PF00067.17 KLO13829.1 - 1.3e-69 234.9 0.0 2.7e-69 233.9 0.0 1.4 1 1 0 1 1 1 1 Cytochrome P450 PAM2 PF07145.10 KLO13829.1 - 1.3 8.7 5.4 0.3 10.6 0.9 2.2 2 0 0 2 2 2 0 Ataxin-2 C-terminal region p450 PF00067.17 KLO13830.1 - 3.7e-61 207.0 0.0 3.4e-60 203.8 0.0 1.9 1 1 0 1 1 1 1 Cytochrome P450 Peroxidase_2 PF01328.12 KLO13831.1 - 4.2e-18 65.0 0.0 7.5e-18 64.2 0.0 1.3 1 0 0 1 1 1 1 Peroxidase, family 2 HD PF01966.17 KLO13832.1 - 4.9e-13 49.1 1.0 1.2e-12 47.9 0.0 2.1 2 1 0 2 2 2 1 HD domain Peptidase_S10 PF00450.17 KLO13835.1 - 3.9e-80 270.0 0.0 6e-80 269.4 0.0 1.2 1 0 0 1 1 1 1 Serine carboxypeptidase 2OG-FeII_Oxy_2 PF13532.1 KLO13836.1 - 1.9e-29 102.9 0.0 2.1e-29 102.7 0.0 1.0 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.15 KLO13836.1 - 1e-07 32.1 0.1 9.9e-07 28.9 0.0 2.1 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily Tet_JBP PF12851.2 KLO13836.1 - 0.018 14.3 0.0 0.024 13.9 0.0 1.1 1 0 0 1 1 1 0 Oxygenase domain of the 2OGFeDO superfamily BAAT_C PF08840.6 KLO13836.1 - 0.018 14.7 0.0 0.04 13.6 0.0 1.6 1 1 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal RasGEF PF00617.14 KLO13837.1 - 1e-29 103.5 0.0 2e-29 102.6 0.0 1.5 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.15 KLO13837.1 - 1.8e-05 24.7 0.0 4.8e-05 23.3 0.0 1.7 1 0 0 1 1 1 1 RasGEF N-terminal motif DUF202 PF02656.10 KLO13838.1 - 0.26 11.5 8.3 1.2 9.3 0.6 2.6 1 1 2 3 3 3 0 Domain of unknown function (DUF202) T_cell_tran_alt PF15128.1 KLO13838.1 - 0.33 10.4 2.9 0.31 10.4 0.4 2.0 2 0 0 2 2 2 0 T-cell leukemia translocation-altered TraX PF05857.6 KLO13838.1 - 1.8 8.1 10.9 1.3 8.5 6.7 1.3 1 1 0 1 1 1 0 TraX protein PH PF00169.24 KLO13839.1 - 0.013 15.7 0.0 0.035 14.3 0.0 1.7 1 0 0 1 1 1 0 PH domain Tetraspannin PF00335.15 KLO13840.1 - 0.0056 15.9 12.6 0.03 13.6 8.8 2.0 1 1 0 1 1 1 1 Tetraspanin family RFC1 PF08519.7 KLO13842.1 - 1e-51 174.7 0.0 2.2e-50 170.4 0.0 2.5 2 0 0 2 2 2 1 Replication factor RFC1 C terminal domain BRCT PF00533.21 KLO13842.1 - 1.3e-14 54.0 0.0 3.1e-14 52.8 0.0 1.7 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain AAA PF00004.24 KLO13842.1 - 1.5e-09 38.1 0.0 4e-09 36.7 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.10 KLO13842.1 - 6e-08 31.8 0.1 1.2e-05 24.2 0.0 2.6 2 0 0 2 2 2 2 Rad17 cell cycle checkpoint protein AAA_19 PF13245.1 KLO13842.1 - 0.00026 20.6 0.0 0.00077 19.1 0.0 1.7 1 0 0 1 1 1 1 Part of AAA domain AAA_14 PF13173.1 KLO13842.1 - 0.0006 19.7 0.0 0.0025 17.7 0.0 2.2 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 KLO13842.1 - 0.0013 18.8 0.0 0.0055 16.8 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 KLO13842.1 - 0.0023 18.7 2.5 0.0048 17.6 0.0 2.8 3 0 0 3 3 2 1 AAA domain RuvB_N PF05496.7 KLO13842.1 - 0.0027 16.8 0.1 0.0078 15.2 0.0 1.8 1 1 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 KLO13842.1 - 0.0029 17.6 0.0 0.0077 16.2 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.9 KLO13842.1 - 0.019 14.6 0.0 0.11 12.2 0.0 2.4 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) NTPase_1 PF03266.10 KLO13842.1 - 0.021 14.5 0.3 0.072 12.7 0.1 2.0 2 0 0 2 2 2 0 NTPase AAA_18 PF13238.1 KLO13842.1 - 0.031 14.5 0.1 0.031 14.5 0.1 2.9 3 0 0 3 3 2 0 AAA domain AAA_33 PF13671.1 KLO13842.1 - 0.059 13.2 1.2 0.41 10.5 0.0 2.7 3 0 0 3 3 3 0 AAA domain AAA_28 PF13521.1 KLO13842.1 - 0.17 11.8 1.6 0.47 10.3 0.0 2.2 2 0 0 2 2 2 0 AAA domain RasGEF PF00617.14 KLO13843.1 - 2.6e-22 79.4 0.1 7.1e-22 78.0 0.0 1.8 2 0 0 2 2 2 1 RasGEF domain RasGEF_N PF00618.15 KLO13843.1 - 3.3e-05 23.9 0.0 9.8e-05 22.4 0.0 1.8 1 0 0 1 1 1 1 RasGEF N-terminal motif DUF1932 PF09130.6 KLO13843.1 - 0.058 13.1 0.0 0.17 11.6 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1932) DUF202 PF02656.10 KLO13844.1 - 2.1 8.6 12.8 2.3 8.4 2.9 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF202) RasGAP PF00616.14 KLO13845.1 - 3.6e-31 108.3 0.0 5.4e-31 107.7 0.0 1.3 1 0 0 1 1 1 1 GTPase-activator protein for Ras-like GTPase DUF3124 PF11322.3 KLO13845.1 - 0.056 13.3 0.0 0.1 12.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3124) DNA_binding_1 PF01035.15 KLO13847.1 - 9.8e-23 79.7 0.0 1.6e-22 79.0 0.0 1.3 1 0 0 1 1 1 1 6-O-methylguanine DNA methyltransferase, DNA binding domain Abhydrolase_6 PF12697.2 KLO13848.1 - 1.9e-26 93.3 0.8 3.2e-26 92.6 0.6 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KLO13848.1 - 1.4e-17 64.0 0.2 3.3e-17 62.8 0.2 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KLO13848.1 - 8.8e-09 35.2 0.0 2.2e-08 33.9 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 KLO13848.1 - 0.0006 19.6 0.1 0.0015 18.3 0.1 1.7 1 1 0 1 1 1 1 Putative lysophospholipase EHN PF06441.7 KLO13848.1 - 0.01 15.7 0.1 0.027 14.3 0.1 1.7 1 0 0 1 1 1 0 Epoxide hydrolase N terminus Ndr PF03096.9 KLO13848.1 - 0.084 11.3 0.0 0.12 10.7 0.0 1.2 1 0 0 1 1 1 0 Ndr family Spt5-NGN PF03439.8 KLO13849.1 - 9.5e-07 28.4 0.0 2.2e-06 27.3 0.0 1.7 1 0 0 1 1 1 1 Early transcription elongation factor of RNA pol II, NGN section KOW PF00467.24 KLO13849.1 - 0.007 16.0 17.0 0.38 10.5 0.4 6.1 6 0 0 6 6 6 2 KOW motif TOBE_2 PF08402.5 KLO13849.1 - 0.093 12.7 0.6 0.84 9.6 0.1 2.7 2 0 0 2 2 2 0 TOBE domain WD40_alt PF14077.1 KLO13850.1 - 0.014 15.0 0.2 0.044 13.4 0.1 1.9 1 0 0 1 1 1 0 Alternative WD40 repeat motif V-SNARE PF05008.10 KLO13850.1 - 0.09 12.9 1.1 1.6 8.9 0.1 2.7 1 1 2 3 3 3 0 Vesicle transport v-SNARE protein N-terminus Pkinase PF00069.20 KLO13852.1 - 1.5e-29 102.9 0.0 2.8e-29 102.0 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KLO13852.1 - 1.7e-21 76.4 0.0 5.4e-21 74.8 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase Sigma70_ner PF04546.8 KLO13852.1 - 0.038 13.6 0.4 0.1 12.2 0.1 1.8 2 0 0 2 2 2 0 Sigma-70, non-essential region APH PF01636.18 KLO13852.1 - 0.16 11.6 0.0 0.28 10.8 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pkinase PF00069.20 KLO13853.1 - 1.8e-11 43.7 0.0 3e-11 42.9 0.0 1.3 1 1 0 1 1 1 1 Protein kinase domain Imm16 PF15565.1 KLO13853.1 - 0.0073 16.1 0.1 0.016 15.0 0.0 1.6 1 0 0 1 1 1 1 Immunity protein 16 Pkinase_Tyr PF07714.12 KLO13853.1 - 0.011 14.7 0.0 0.025 13.6 0.0 1.5 1 1 0 1 1 1 0 Protein tyrosine kinase Pkinase PF00069.20 KLO13854.1 - 3.9e-07 29.4 0.0 9e-05 21.7 0.0 2.5 1 1 1 2 2 2 2 Protein kinase domain Pkinase PF00069.20 KLO13855.1 - 8.5e-12 44.7 0.0 1.4e-11 44.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KLO13855.1 - 0.0028 16.7 0.0 0.0065 15.5 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 KLO13855.1 - 0.018 14.8 1.9 1.4 8.5 0.1 2.3 1 1 1 2 2 2 0 Phosphotransferase enzyme family Pkinase PF00069.20 KLO13856.1 - 7.8e-09 35.0 0.0 7.8e-07 28.4 0.0 2.6 2 1 1 3 3 3 1 Protein kinase domain Imm16 PF15565.1 KLO13856.1 - 0.039 13.8 0.0 0.082 12.7 0.0 1.5 1 0 0 1 1 1 0 Immunity protein 16 Pkinase_Tyr PF07714.12 KLO13856.1 - 0.057 12.4 0.0 0.11 11.5 0.0 1.4 1 0 0 1 1 1 0 Protein tyrosine kinase Pkinase PF00069.20 KLO13857.1 - 2.3e-13 49.8 0.0 9.1e-12 44.6 0.0 2.2 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 KLO13857.1 - 0.0016 17.5 0.1 0.0034 16.5 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase RIO1 PF01163.17 KLO13857.1 - 0.091 12.0 0.1 0.14 11.4 0.1 1.2 1 0 0 1 1 1 0 RIO1 family Pkinase PF00069.20 KLO13858.1 - 4.7e-12 45.6 0.0 3e-10 39.6 0.0 2.1 1 1 1 2 2 2 2 Protein kinase domain APH PF01636.18 KLO13858.1 - 0.014 15.1 0.0 0.03 14.0 0.0 1.6 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pkinase_Tyr PF07714.12 KLO13858.1 - 0.083 11.9 0.0 0.14 11.1 0.0 1.4 1 0 0 1 1 1 0 Protein tyrosine kinase Pkinase PF00069.20 KLO13860.1 - 1.1e-30 106.7 0.0 1.3e-30 106.4 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KLO13860.1 - 2.8e-20 72.4 0.0 4.1e-20 71.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.17 KLO13860.1 - 0.013 14.8 0.0 0.018 14.4 0.0 1.2 1 0 0 1 1 1 0 RIO1 family EcKinase PF02958.15 KLO13860.1 - 0.026 13.6 0.1 0.063 12.4 0.0 1.5 2 0 0 2 2 2 0 Ecdysteroid kinase CENP-F_leu_zip PF10473.4 KLO13861.1 - 0.01 15.7 20.5 0.01 15.7 14.2 7.4 2 1 5 7 7 7 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Myosin_tail_1 PF01576.14 KLO13861.1 - 2.9 5.4 137.3 0.028 12.1 10.9 4.8 2 1 1 4 4 4 0 Myosin tail Pkinase PF00069.20 KLO13862.1 - 2.3e-14 53.2 0.0 1.4e-12 47.3 0.0 2.3 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 KLO13862.1 - 0.0001 21.4 0.0 0.00055 19.0 0.0 2.0 3 0 0 3 3 3 1 Protein tyrosine kinase RIO1 PF01163.17 KLO13862.1 - 0.022 14.0 0.0 0.041 13.2 0.0 1.3 1 0 0 1 1 1 0 RIO1 family Pkinase PF00069.20 KLO13863.1 - 1.9e-21 76.3 0.0 3.3e-21 75.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KLO13863.1 - 7.9e-15 54.6 0.0 1.3e-14 53.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 KLO13863.1 - 6.9e-05 22.6 0.4 0.00015 21.6 0.1 1.6 2 0 0 2 2 2 1 Phosphotransferase enzyme family EcKinase PF02958.15 KLO13863.1 - 0.0036 16.4 0.0 0.0073 15.4 0.0 1.5 1 0 0 1 1 1 1 Ecdysteroid kinase RIO1 PF01163.17 KLO13863.1 - 0.023 14.0 0.0 0.052 12.8 0.0 1.5 1 0 0 1 1 1 0 RIO1 family DUF2398 PF09661.5 KLO13863.1 - 0.056 12.1 1.4 1.5 7.4 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2398) WD40 PF00400.27 KLO13864.1 - 8.1e-11 41.3 0.1 8.4e-09 34.9 0.0 3.2 3 0 0 3 3 3 1 WD domain, G-beta repeat Pkinase PF00069.20 KLO13867.1 - 2.8e-46 157.8 0.0 4e-46 157.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KLO13867.1 - 5.7e-40 137.0 0.0 8.1e-40 136.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KLO13867.1 - 0.00014 20.9 0.0 0.00031 19.8 0.0 1.5 2 0 0 2 2 2 1 Kinase-like RIO1 PF01163.17 KLO13867.1 - 0.018 14.4 0.0 0.16 11.2 0.0 2.1 2 0 0 2 2 2 0 RIO1 family Kdo PF06293.9 KLO13867.1 - 0.019 14.0 0.0 0.038 13.0 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Asp PF00026.18 KLO13868.1 - 5.1e-09 35.8 0.0 3.7e-05 23.1 0.0 2.9 2 1 0 2 2 2 2 Eukaryotic aspartyl protease HEAT_2 PF13646.1 KLO13870.1 - 1.2e-15 57.5 23.7 4.3e-05 23.7 1.3 9.2 5 4 3 9 9 9 6 HEAT repeats HEAT PF02985.17 KLO13870.1 - 5.4e-15 54.0 19.0 0.014 15.3 0.1 11.3 12 0 0 12 12 12 4 HEAT repeat HEAT_EZ PF13513.1 KLO13870.1 - 1.1e-12 47.9 40.6 0.005 17.2 0.0 13.8 12 2 2 15 15 15 5 HEAT-like repeat IBN_N PF03810.14 KLO13870.1 - 5.9e-07 29.3 0.5 2.1e-06 27.5 0.4 2.1 1 0 0 1 1 1 1 Importin-beta N-terminal domain Ipi1_N PF12333.3 KLO13870.1 - 0.00018 21.4 0.0 0.69 9.9 0.0 5.3 5 1 1 6 6 6 1 Rix1 complex component involved in 60S ribosome maturation Clat_adaptor_s PF01217.15 KLO13873.1 - 3.7e-56 188.8 2.6 4e-56 188.6 1.8 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain UTP15_C PF09384.5 KLO13873.1 - 0.074 12.7 0.2 5.2 6.7 0.0 2.1 1 1 1 2 2 2 0 UTP15 C terminal Pkinase PF00069.20 KLO13874.1 - 3.9e-06 26.2 0.0 5.2e-06 25.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KLO13874.1 - 5.2e-06 25.7 0.0 8.2e-06 25.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 KLO13875.1 - 4.6e-40 137.3 0.0 5.8e-40 137.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KLO13875.1 - 8.6e-36 123.3 0.0 1.1e-35 122.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.17 KLO13875.1 - 0.00078 18.8 0.1 0.008 15.5 0.0 2.0 2 0 0 2 2 2 1 RIO1 family Kinase-like PF14531.1 KLO13875.1 - 0.0022 17.0 0.0 0.0054 15.7 0.0 1.5 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.9 KLO13875.1 - 0.05 12.6 0.0 0.089 11.8 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KLO13875.1 - 0.14 11.9 0.0 0.26 10.9 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pkinase PF00069.20 KLO13876.1 - 3.9e-43 147.4 0.0 4.9e-43 147.1 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KLO13876.1 - 4.9e-38 130.6 0.0 6e-38 130.4 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KLO13876.1 - 2.1e-08 33.4 0.0 3.2e-08 32.9 0.0 1.2 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.17 KLO13876.1 - 0.005 16.2 0.0 0.025 13.9 0.0 1.9 2 0 0 2 2 2 1 RIO1 family APH PF01636.18 KLO13876.1 - 0.007 16.1 0.0 0.012 15.3 0.0 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 KLO13876.1 - 0.015 14.4 0.0 0.021 13.8 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.20 KLO13879.1 - 8.8e-47 159.4 0.0 1.2e-46 158.9 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KLO13879.1 - 5.6e-41 140.3 0.0 8e-41 139.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KLO13879.1 - 0.0027 16.7 0.0 0.0055 15.7 0.0 1.4 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.17 KLO13879.1 - 0.014 14.7 0.0 0.11 11.8 0.0 2.0 2 0 0 2 2 2 0 RIO1 family Kdo PF06293.9 KLO13879.1 - 0.091 11.8 0.0 0.16 10.9 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KLO13879.1 - 0.11 12.2 0.0 0.37 10.4 0.0 2.0 2 1 0 2 2 2 0 Phosphotransferase enzyme family Pkinase PF00069.20 KLO13881.1 - 4.1e-45 153.9 0.0 5.1e-45 153.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KLO13881.1 - 1.1e-39 136.1 0.0 1.4e-39 135.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KLO13881.1 - 4.3e-05 22.6 0.0 6.8e-05 21.9 0.0 1.3 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.17 KLO13881.1 - 0.0066 15.8 0.1 0.074 12.3 0.0 2.0 2 0 0 2 2 2 1 RIO1 family Kdo PF06293.9 KLO13881.1 - 0.013 14.6 0.0 0.021 13.8 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KLO13881.1 - 0.041 13.6 0.0 0.2 11.3 0.0 1.8 1 1 1 2 2 2 0 Phosphotransferase enzyme family Pkinase PF00069.20 KLO13882.1 - 2e-77 259.8 0.0 1.6e-41 142.1 0.0 2.0 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 KLO13882.1 - 7.6e-70 234.9 0.2 5.2e-36 124.0 0.2 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 KLO13882.1 - 7.2e-08 31.7 0.3 0.0027 16.7 0.0 2.5 2 1 0 2 2 2 2 Kinase-like RIO1 PF01163.17 KLO13882.1 - 0.00072 18.9 0.0 0.046 13.0 0.0 2.6 2 1 0 2 2 2 1 RIO1 family Kdo PF06293.9 KLO13882.1 - 0.11 11.5 0.0 0.91 8.5 0.0 2.1 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.20 KLO13883.1 - 3.3e-12 46.1 0.0 4.2e-12 45.7 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KLO13883.1 - 7.4e-10 38.3 0.0 8.6e-10 38.1 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase DUF4248 PF14053.1 KLO13883.1 - 0.07 12.7 0.1 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4248) Herpes_U5 PF05999.6 KLO13884.1 - 0.023 13.3 0.1 0.031 12.8 0.1 1.1 1 0 0 1 1 1 0 Herpesvirus U5-like family Pkinase PF00069.20 KLO13888.1 - 2.3e-44 151.5 0.0 2.9e-44 151.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KLO13888.1 - 1.1e-40 139.4 0.0 1.4e-40 139.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KLO13888.1 - 0.00035 19.6 0.0 0.00077 18.5 0.0 1.5 1 1 0 1 1 1 1 Kinase-like RIO1 PF01163.17 KLO13888.1 - 0.015 14.6 0.4 0.15 11.4 0.0 2.0 2 0 0 2 2 2 0 RIO1 family DUF3114 PF11311.3 KLO13888.1 - 0.024 13.9 0.0 2.6 7.3 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3114) Kdo PF06293.9 KLO13888.1 - 0.071 12.1 0.0 0.15 11.0 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family FrhB_FdhB_N PF04422.8 KLO13888.1 - 0.084 12.7 0.0 0.22 11.4 0.0 1.6 1 0 0 1 1 1 0 Coenzyme F420 hydrogenase/dehydrogenase, beta subunit N-term DUF3873 PF12989.2 KLO13889.1 - 0.32 11.1 2.3 1.2 9.3 1.1 2.2 2 1 1 3 3 3 0 Domain of unknown function, B. Theta Gene description (DUF3873) Pkinase PF00069.20 KLO13891.1 - 5.5e-44 150.2 0.0 7.6e-44 149.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KLO13891.1 - 2e-39 135.2 0.0 2.6e-39 134.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KLO13891.1 - 0.00032 19.7 0.0 0.00053 19.0 0.0 1.3 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.17 KLO13891.1 - 0.0088 15.4 0.5 0.11 11.7 0.0 2.1 2 0 0 2 2 2 1 RIO1 family Kdo PF06293.9 KLO13891.1 - 0.098 11.7 0.0 0.19 10.7 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Exonuc_VII_S PF02609.11 KLO13893.1 - 4.5 7.1 10.9 0.099 12.4 0.7 2.9 3 0 0 3 3 3 0 Exonuclease VII small subunit Pkinase PF00069.20 KLO13898.1 - 1.5e-72 243.9 0.0 9.7e-42 142.9 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 KLO13898.1 - 5.6e-69 232.0 0.0 9.9e-36 123.1 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 KLO13898.1 - 5.6e-09 35.3 0.0 0.002 17.1 0.0 2.4 2 0 0 2 2 2 2 Kinase-like Kdo PF06293.9 KLO13898.1 - 0.027 13.5 0.0 0.21 10.6 0.0 2.2 3 0 0 3 3 3 0 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 KLO13898.1 - 0.048 13.0 0.0 0.3 10.4 0.0 2.1 2 0 0 2 2 2 0 RIO1 family APH PF01636.18 KLO13898.1 - 0.12 12.0 0.0 0.22 11.2 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family DUF4248 PF14053.1 KLO13898.1 - 0.15 11.6 0.0 0.83 9.2 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4248) Pkinase PF00069.20 KLO13900.1 - 2e-72 243.5 0.0 3.5e-42 144.3 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 KLO13900.1 - 2e-66 223.7 0.2 5.4e-37 127.2 0.0 2.5 2 1 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 KLO13900.1 - 7.7e-10 38.2 0.1 5.2e-05 22.3 0.0 2.9 2 1 0 2 2 2 2 Kinase-like RIO1 PF01163.17 KLO13900.1 - 0.018 14.3 0.0 0.1 11.9 0.0 2.1 2 0 0 2 2 2 0 RIO1 family APH PF01636.18 KLO13900.1 - 0.02 14.6 0.1 0.059 13.1 0.0 1.8 2 0 0 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.9 KLO13900.1 - 0.022 13.8 0.0 0.37 9.8 0.0 2.2 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family HARP PF07443.8 KLO13900.1 - 0.023 14.0 0.2 6.9 6.1 0.0 2.6 2 0 0 2 2 2 0 HepA-related protein (HARP) Me-amine-dh_L PF02975.9 KLO13900.1 - 0.08 12.9 0.0 0.2 11.6 0.0 1.6 1 0 0 1 1 1 0 Methylamine dehydrogenase, L chain LIME1 PF15332.1 KLO13900.1 - 0.11 11.6 0.0 0.19 10.9 0.0 1.2 1 0 0 1 1 1 0 Lck-interacting transmembrane adapter 1 Aldolase_II PF00596.16 KLO13901.1 - 2.2e-45 154.5 0.0 2.7e-45 154.2 0.0 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain Pkinase PF00069.20 KLO13904.1 - 1.5e-13 50.5 0.0 2e-13 50.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KLO13904.1 - 1.9e-08 33.6 0.0 2.6e-08 33.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KLO13904.1 - 0.033 13.1 0.1 0.038 12.9 0.1 1.2 1 0 0 1 1 1 0 Kinase-like Pkinase PF00069.20 KLO13905.1 - 3.4e-35 121.4 0.0 4.1e-35 121.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KLO13905.1 - 1.3e-31 109.6 0.0 1.6e-31 109.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KLO13905.1 - 9.4e-08 31.3 0.0 1.3e-07 30.8 0.0 1.1 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 KLO13905.1 - 0.0088 15.1 0.0 0.012 14.6 0.0 1.1 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 KLO13905.1 - 0.014 14.7 0.0 0.019 14.3 0.0 1.2 1 0 0 1 1 1 0 RIO1 family APH PF01636.18 KLO13905.1 - 0.04 13.6 0.0 0.063 12.9 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Methyltransf_2 PF00891.13 KLO13906.1 - 2.4e-30 105.4 0.1 1.7e-28 99.4 0.0 2.2 2 0 0 2 2 2 1 O-methyltransferase Dimerisation PF08100.6 KLO13906.1 - 0.00016 21.4 0.1 0.00035 20.3 0.1 1.6 1 0 0 1 1 1 1 Dimerisation domain MTS PF05175.9 KLO13906.1 - 0.00024 20.5 0.0 0.00047 19.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_18 PF12847.2 KLO13906.1 - 0.014 15.9 0.0 0.034 14.7 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.1 KLO13906.1 - 0.015 14.9 0.0 0.03 13.9 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain DOT1 PF08123.8 KLO13906.1 - 0.019 14.2 0.0 0.045 13.0 0.0 1.5 2 0 0 2 2 2 0 Histone methylation protein DOT1 Methyltransf_4 PF02390.12 KLO13906.1 - 0.036 13.1 0.0 0.058 12.4 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase Methyltransf_12 PF08242.7 KLO13906.1 - 0.039 14.4 0.0 0.085 13.3 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_25 PF13649.1 KLO13906.1 - 0.12 12.7 0.0 0.28 11.5 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Pkinase PF00069.20 KLO13908.1 - 6.2e-31 107.4 0.0 7.2e-31 107.2 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KLO13908.1 - 7.4e-27 94.0 0.0 8.9e-27 93.7 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KLO13908.1 - 2.2e-05 23.5 0.0 3.2e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 KLO13908.1 - 0.018 14.1 0.0 0.021 13.9 0.0 1.1 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 KLO13908.1 - 0.018 14.3 0.0 0.024 13.9 0.0 1.3 1 0 0 1 1 1 0 RIO1 family APH PF01636.18 KLO13908.1 - 0.097 12.3 0.0 0.13 11.9 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family UPF0175 PF03683.8 KLO13909.1 - 0.14 11.6 0.4 1.5 8.3 0.0 2.1 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0175) SpoVIF PF14069.1 KLO13909.1 - 0.14 11.8 0.3 0.57 9.9 0.1 1.9 2 0 0 2 2 2 0 Stage VI sporulation protein F KIP1 PF07765.7 KLO13909.1 - 0.15 11.9 0.4 1.1 9.1 0.0 2.3 3 0 0 3 3 3 0 KIP1-like protein DDE_1 PF03184.14 KLO13910.1 - 2.5e-18 66.0 0.0 2.7e-18 65.8 0.0 1.0 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_3 PF13358.1 KLO13910.1 - 0.0022 17.7 0.0 0.0026 17.4 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease Pkinase PF00069.20 KLO13914.1 - 8.2e-31 107.0 0.1 9.5e-31 106.8 0.1 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KLO13914.1 - 1.1e-30 106.6 0.2 1.3e-30 106.4 0.1 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KLO13914.1 - 7.3e-05 21.8 0.0 0.00012 21.1 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 KLO13914.1 - 0.0016 18.1 0.0 0.0023 17.7 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.17 KLO13914.1 - 0.031 13.6 0.0 0.037 13.3 0.0 1.2 1 0 0 1 1 1 0 RIO1 family Kdo PF06293.9 KLO13914.1 - 0.14 11.2 0.0 0.15 11.1 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Methyltransf_2 PF00891.13 KLO13915.1 - 9.7e-30 103.5 0.0 1.7e-29 102.7 0.0 1.4 1 0 0 1 1 1 1 O-methyltransferase MTS PF05175.9 KLO13915.1 - 6.3e-05 22.4 0.0 0.00011 21.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_18 PF12847.2 KLO13915.1 - 0.0014 19.1 0.1 0.0057 17.2 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 KLO13915.1 - 0.0016 18.1 0.0 0.02 14.6 0.0 2.2 1 1 1 2 2 2 1 Methyltransferase domain Dimerisation PF08100.6 KLO13915.1 - 0.0036 17.0 0.1 0.0081 15.9 0.0 1.5 1 0 0 1 1 1 1 Dimerisation domain Methyltransf_12 PF08242.7 KLO13915.1 - 0.019 15.3 0.0 0.045 14.2 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.1 KLO13915.1 - 0.021 14.3 0.0 0.037 13.6 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_4 PF02390.12 KLO13915.1 - 0.051 12.6 0.0 0.098 11.6 0.0 1.4 1 0 0 1 1 1 0 Putative methyltransferase Pkinase PF00069.20 KLO13917.1 - 2.3e-31 108.9 0.0 2.7e-31 108.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KLO13917.1 - 5.6e-26 91.1 0.0 6.8e-26 90.8 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 KLO13917.1 - 0.0082 15.2 0.0 0.0089 15.1 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 KLO13917.1 - 0.012 14.6 0.0 0.017 14.1 0.0 1.1 1 0 0 1 1 1 0 Kinase-like Clat_adaptor_s PF01217.15 KLO13919.1 - 6.5e-57 191.2 3.2 7.1e-57 191.1 2.2 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Mpv17_PMP22 PF04117.7 KLO13920.1 - 8.1e-09 34.9 0.8 1.4e-08 34.2 0.4 1.5 1 1 0 1 1 1 1 Mpv17 / PMP22 family NRDE-2 PF08424.5 KLO13922.1 - 1.3e-54 185.3 0.4 9.4e-54 182.4 0.2 2.1 2 0 0 2 2 2 1 NRDE-2, necessary for RNA interference TPR_14 PF13428.1 KLO13922.1 - 5.7e-06 26.5 1.3 0.013 16.0 0.0 5.7 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_15 PF13429.1 KLO13922.1 - 0.00064 18.8 0.2 0.0087 15.1 0.1 2.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.1 KLO13922.1 - 0.013 16.1 0.4 0.16 12.6 0.0 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_19 PF14559.1 KLO13922.1 - 0.014 15.7 0.1 1.6 9.1 0.0 4.0 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_2 PF07719.12 KLO13922.1 - 0.017 15.0 0.1 0.15 12.0 0.0 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.1 KLO13922.1 - 0.025 14.4 0.0 0.088 12.7 0.0 1.9 1 0 0 1 1 1 0 Tetratricopeptide repeat UPF0113 PF03657.8 KLO13923.1 - 9.5e-11 41.6 0.0 1.2e-10 41.2 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0113) MFS_1 PF07690.11 KLO13925.1 - 2.9e-32 111.7 31.2 2.9e-32 111.7 21.6 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily MFS_1 PF07690.11 KLO13926.1 - 4.9e-29 101.1 24.1 4.9e-29 101.1 16.7 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily Peptidase_M41 PF01434.13 KLO13927.1 - 1.6e-72 243.4 0.0 2.4e-72 242.8 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.24 KLO13927.1 - 9.5e-43 145.5 0.0 1.9e-42 144.6 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) FtsH_ext PF06480.10 KLO13927.1 - 2.1e-12 47.1 0.0 5e-12 45.9 0.0 1.6 1 0 0 1 1 1 1 FtsH Extracellular AAA_17 PF13207.1 KLO13927.1 - 0.0015 19.3 0.0 0.0058 17.4 0.0 2.1 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 KLO13927.1 - 0.0025 17.9 0.0 0.13 12.4 0.1 2.5 1 1 0 2 2 2 1 AAA domain AAA_19 PF13245.1 KLO13927.1 - 0.0034 17.0 0.4 0.01 15.5 0.3 1.8 1 0 0 1 1 1 1 Part of AAA domain TIP49 PF06068.8 KLO13927.1 - 0.0042 15.8 0.0 0.0069 15.1 0.0 1.3 1 0 0 1 1 1 1 TIP49 C-terminus AAA_5 PF07728.9 KLO13927.1 - 0.0087 15.7 0.0 0.031 13.9 0.0 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 KLO13927.1 - 0.013 15.5 0.1 0.11 12.5 0.1 2.3 1 1 1 2 2 2 0 AAA ATPase domain RuvB_N PF05496.7 KLO13927.1 - 0.015 14.3 0.0 0.025 13.6 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus IstB_IS21 PF01695.12 KLO13927.1 - 0.027 13.8 0.0 0.061 12.7 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein Zeta_toxin PF06414.7 KLO13927.1 - 0.029 13.4 0.0 0.061 12.4 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin AAA_2 PF07724.9 KLO13927.1 - 0.032 14.1 0.0 0.13 12.1 0.0 2.0 2 0 0 2 2 1 0 AAA domain (Cdc48 subfamily) AAA_25 PF13481.1 KLO13927.1 - 0.055 12.8 0.4 0.17 11.2 0.2 1.9 1 1 0 1 1 1 0 AAA domain Mg_chelatase PF01078.16 KLO13927.1 - 0.16 11.1 0.1 0.37 9.9 0.1 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI DSPc PF00782.15 KLO13928.1 - 2.2e-19 69.3 0.0 1.4e-13 50.5 0.0 3.1 2 1 0 2 2 2 2 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 KLO13928.1 - 0.0017 17.7 0.0 0.0027 17.0 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.1 KLO13928.1 - 0.14 12.2 0.0 0.29 11.1 0.0 1.5 1 0 0 1 1 1 0 Inositol hexakisphosphate DUF846 PF05832.7 KLO13929.1 - 7.1e-55 184.6 8.2 9.5e-55 184.2 5.7 1.2 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF846) Nucleoside_tran PF01733.13 KLO13929.1 - 0.013 14.6 2.5 0.41 9.7 0.6 2.0 2 0 0 2 2 2 0 Nucleoside transporter SPRY PF00622.23 KLO13930.1 - 1.4e-18 67.1 0.0 2.2e-18 66.5 0.0 1.3 1 0 0 1 1 1 1 SPRY domain CBS PF00571.23 KLO13931.1 - 2.1e-24 84.9 2.6 4.7e-12 45.5 0.0 4.4 4 0 0 4 4 4 4 CBS domain DUF1195 PF06708.6 KLO13931.1 - 0.13 11.6 0.0 0.24 10.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1195) Methyltransf_23 PF13489.1 KLO13932.1 - 1.1e-08 34.9 0.0 1.8e-08 34.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Polyketide_cyc2 PF10604.4 KLO13932.1 - 2.1e-06 27.9 0.1 3.8e-06 27.1 0.0 1.4 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Methyltransf_18 PF12847.2 KLO13932.1 - 0.00027 21.4 0.0 0.00053 20.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KLO13932.1 - 0.02 14.9 0.1 0.29 11.1 0.0 2.5 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_12 PF08242.7 KLO13932.1 - 0.022 15.2 0.0 0.062 13.7 0.0 1.9 1 1 0 1 1 1 0 Methyltransferase domain PX PF00787.19 KLO13933.1 - 9.4e-16 57.6 0.0 1.6e-15 56.8 0.0 1.4 1 0 0 1 1 1 1 PX domain SNARE PF05739.14 KLO13933.1 - 3.9e-12 45.6 4.2 3.9e-12 45.6 2.9 2.1 2 0 0 2 2 2 1 SNARE domain SurA_N PF09312.6 KLO13933.1 - 0.028 14.2 2.2 0.065 13.0 1.5 1.6 1 0 0 1 1 1 0 SurA N-terminal domain Nucleoporin_FG PF13634.1 KLO13933.1 - 0.029 14.6 0.4 0.049 13.8 0.3 1.3 1 0 0 1 1 1 0 Nucleoporin FG repeat region Rhodanese PF00581.15 KLO13935.1 - 2.1e-18 66.7 0.0 3.2e-18 66.1 0.0 1.3 1 0 0 1 1 1 1 Rhodanese-like domain Multi_ubiq PF14452.1 KLO13935.1 - 0.0018 18.2 0.1 0.0032 17.3 0.0 1.4 1 0 0 1 1 1 1 Multiubiquitin Ctr PF04145.10 KLO13936.1 - 9.6e-24 84.0 0.2 1.2e-23 83.7 0.1 1.1 1 0 0 1 1 1 1 Ctr copper transporter family DUF515 PF04415.7 KLO13937.1 - 0.18 10.0 2.0 0.23 9.6 1.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF515) Frataxin_Cyay PF01491.11 KLO13939.1 - 9.2e-32 109.0 0.0 1.2e-31 108.7 0.0 1.1 1 0 0 1 1 1 1 Frataxin-like domain Bromodomain PF00439.20 KLO13940.1 - 8.7e-36 121.7 0.1 7.2e-19 67.5 0.0 2.5 2 0 0 2 2 2 2 Bromodomain WD40 PF00400.27 KLO13940.1 - 4.9e-22 76.9 13.4 2.5e-06 27.1 0.1 7.2 7 0 0 7 7 7 4 WD domain, G-beta repeat FlxA PF14282.1 KLO13940.1 - 0.069 13.1 12.1 0.037 13.9 6.5 2.1 2 0 0 2 2 2 0 FlxA-like protein DUF1664 PF07889.7 KLO13940.1 - 0.075 12.8 1.1 0.11 12.2 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Nup88 PF10168.4 KLO13940.1 - 0.42 8.3 0.0 0.42 8.3 0.0 1.9 2 0 0 2 2 2 0 Nuclear pore component RRM_6 PF14259.1 KLO13941.1 - 6e-08 32.5 0.0 1.3e-05 25.0 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) PWI PF01480.12 KLO13941.1 - 4.6e-06 26.6 0.0 8.5e-06 25.7 0.0 1.4 1 0 0 1 1 1 1 PWI domain zf-CCCH PF00642.19 KLO13941.1 - 2e-05 24.1 2.7 3.3e-05 23.4 1.9 1.3 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) DUF2414 PF10309.4 KLO13941.1 - 0.1 12.2 0.2 0.29 10.8 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2414) RRM_3 PF08777.6 KLO13941.1 - 0.16 11.8 0.1 1.3 8.9 0.0 2.3 2 0 0 2 2 2 0 RNA binding motif Sel1 PF08238.7 KLO13942.1 - 1.3e-19 70.1 12.8 2.4e-07 31.1 1.4 3.8 4 0 0 4 4 4 3 Sel1 repeat TPR_2 PF07719.12 KLO13942.1 - 0.0011 18.6 7.9 0.034 14.0 0.0 3.9 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.1 KLO13942.1 - 0.0011 19.3 1.8 13 6.7 0.2 3.7 2 2 1 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.1 KLO13942.1 - 0.003 18.1 3.2 0.034 14.8 0.1 2.9 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.1 KLO13942.1 - 0.0053 16.3 3.9 0.02 14.5 0.1 2.6 2 1 0 2 2 2 1 TPR repeat TPR_1 PF00515.23 KLO13942.1 - 0.0066 16.0 1.7 0.057 13.0 0.0 3.0 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.1 KLO13942.1 - 0.17 11.8 2.1 5.1 7.0 0.0 3.0 3 1 0 3 3 3 0 Tetratricopeptide repeat DEAD PF00270.24 KLO13943.1 - 3.1e-19 69.0 0.0 7e-19 67.9 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KLO13943.1 - 4e-18 65.0 0.3 9.3e-18 63.8 0.2 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 KLO13943.1 - 2e-17 63.5 0.0 1e-16 61.3 0.0 2.2 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_22 PF13401.1 KLO13943.1 - 0.01 16.0 0.0 0.066 13.3 0.0 2.3 1 1 1 2 2 2 0 AAA domain PolC_DP2 PF03833.8 KLO13944.1 - 0.16 9.6 0.0 0.23 9.0 0.0 1.2 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 FYRN PF05964.9 KLO13945.1 - 0.11 11.9 0.0 0.16 11.4 0.0 1.2 1 0 0 1 1 1 0 F/Y-rich N-terminus G-patch PF01585.18 KLO13946.1 - 9.9e-11 41.2 0.1 2.2e-10 40.1 0.1 1.6 1 0 0 1 1 1 1 G-patch domain zf-C2H2_jaz PF12171.3 KLO13946.1 - 4.4e-06 26.6 5.5 9.3e-06 25.6 3.8 1.6 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 KLO13946.1 - 9e-05 22.5 1.3 0.0002 21.4 0.9 1.6 1 0 0 1 1 1 1 Zinc-finger of C2H2 type G-patch_2 PF12656.2 KLO13946.1 - 0.0003 20.5 0.5 0.00069 19.4 0.0 1.9 2 0 0 2 2 2 1 DExH-box splicing factor binding site zf-C2H2_2 PF12756.2 KLO13946.1 - 0.014 15.5 0.7 0.024 14.7 0.5 1.3 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) Thioredoxin_2 PF13098.1 KLO13946.1 - 0.45 10.7 2.4 1.1 9.4 0.5 2.2 2 0 0 2 2 2 0 Thioredoxin-like domain bZIP_1 PF00170.16 KLO13948.1 - 2.5e-07 30.5 11.8 2.5e-07 30.5 8.2 5.4 5 2 1 6 6 6 1 bZIP transcription factor bZIP_2 PF07716.10 KLO13948.1 - 2.8e-07 30.2 13.6 2.8e-07 30.2 9.4 5.2 5 1 1 6 6 6 1 Basic region leucine zipper bZIP_Maf PF03131.12 KLO13948.1 - 0.024 14.9 8.7 0.024 14.9 6.0 5.4 3 1 2 5 5 5 0 bZIP Maf transcription factor RIC3 PF15361.1 KLO13948.1 - 0.13 12.5 0.3 0.13 12.5 0.2 3.4 4 1 0 4 4 4 0 Resistance to inhibitors of cholinesterase homologue 3 SpecificRecomb PF10136.4 KLO13948.1 - 1.7 6.5 13.2 3.6 5.4 9.1 1.4 1 0 0 1 1 1 0 Site-specific recombinase PXA PF02194.10 KLO13949.1 - 6e-29 100.9 0.0 1e-28 100.2 0.0 1.4 1 0 0 1 1 1 1 PXA domain Nexin_C PF08628.7 KLO13949.1 - 0.17 11.9 0.0 0.39 10.8 0.0 1.7 1 0 0 1 1 1 0 Sorting nexin C terminal Glucosamine_iso PF01182.15 KLO13951.1 - 3.8e-64 216.0 0.0 5.1e-64 215.6 0.0 1.2 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase THAP PF05485.7 KLO13951.1 - 0.015 15.4 0.1 0.047 13.8 0.1 1.8 2 0 0 2 2 2 0 THAP domain Peptidase_M28 PF04389.12 KLO13952.1 - 2.7e-29 102.1 0.0 4.4e-29 101.4 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 Aminotran_4 PF01063.14 KLO13953.1 - 9.4e-25 87.4 0.0 1.1e-24 87.1 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class IV Ras PF00071.17 KLO13954.1 - 7.3e-59 197.7 0.4 8.6e-59 197.5 0.3 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KLO13954.1 - 2e-19 70.2 0.0 3.6e-19 69.3 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KLO13954.1 - 9.6e-16 57.5 0.1 1.1e-15 57.2 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 KLO13954.1 - 2.7e-08 33.2 0.1 3.2e-08 32.9 0.1 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 KLO13954.1 - 3.3e-08 33.2 0.1 3.9e-07 29.6 0.0 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 KLO13954.1 - 9.9e-08 31.9 0.0 1.4e-07 31.4 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase ATP_bind_1 PF03029.12 KLO13954.1 - 0.0002 20.9 0.4 0.013 15.0 0.0 2.1 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein AAA_22 PF13401.1 KLO13954.1 - 0.00024 21.2 0.0 0.00041 20.4 0.0 1.6 1 1 0 1 1 1 1 AAA domain Septin PF00735.13 KLO13954.1 - 0.00027 20.0 0.9 0.012 14.6 0.1 2.4 2 1 0 3 3 3 1 Septin PduV-EutP PF10662.4 KLO13954.1 - 0.00029 20.3 0.3 0.083 12.3 0.1 2.3 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation SRPRB PF09439.5 KLO13954.1 - 0.00033 19.9 0.0 0.00045 19.5 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit DUF258 PF03193.11 KLO13954.1 - 0.00068 18.8 0.1 0.0013 17.9 0.1 1.5 1 1 0 1 1 1 1 Protein of unknown function, DUF258 Arch_ATPase PF01637.13 KLO13954.1 - 0.0031 17.2 0.1 0.0053 16.4 0.0 1.5 2 0 0 2 2 2 1 Archaeal ATPase cobW PF02492.14 KLO13954.1 - 0.0034 16.8 0.1 0.0092 15.4 0.1 1.8 1 1 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain AAA_24 PF13479.1 KLO13954.1 - 0.0046 16.5 0.3 0.011 15.3 0.0 1.7 2 0 0 2 2 2 1 AAA domain MobB PF03205.9 KLO13954.1 - 0.0054 16.4 0.1 0.014 15.1 0.1 1.6 1 1 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_10 PF12846.2 KLO13954.1 - 0.011 15.1 0.1 0.023 14.1 0.0 1.4 1 1 0 1 1 1 0 AAA-like domain AAA_16 PF13191.1 KLO13954.1 - 0.013 15.5 0.0 0.016 15.1 0.0 1.6 1 1 0 1 1 1 0 AAA ATPase domain AAA_5 PF07728.9 KLO13954.1 - 0.016 14.8 0.1 0.21 11.3 0.0 2.1 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) NTPase_1 PF03266.10 KLO13954.1 - 0.02 14.6 0.1 0.039 13.6 0.0 1.5 2 0 0 2 2 2 0 NTPase FeoB_N PF02421.13 KLO13954.1 - 0.024 13.9 0.0 0.47 9.7 0.0 2.2 2 0 0 2 2 2 0 Ferrous iron transport protein B NACHT PF05729.7 KLO13954.1 - 0.058 13.0 0.0 0.095 12.3 0.0 1.3 1 0 0 1 1 1 0 NACHT domain AAA_14 PF13173.1 KLO13954.1 - 0.08 12.8 0.0 0.16 11.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.22 KLO13954.1 - 0.088 13.1 1.2 0.21 11.8 0.9 1.9 1 1 0 1 1 1 0 ABC transporter NB-ARC PF00931.17 KLO13954.1 - 0.11 11.2 0.1 0.16 10.7 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain ATG16 PF08614.6 KLO13955.1 - 4.7e-44 150.5 18.4 7e-44 149.9 12.8 1.3 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) TMF_TATA_bd PF12325.3 KLO13955.1 - 0.0039 16.9 23.5 0.038 13.7 6.8 3.1 2 1 1 3 3 3 2 TATA element modulatory factor 1 TATA binding IncA PF04156.9 KLO13955.1 - 0.0041 16.7 20.4 0.013 15.0 3.6 2.7 1 1 1 2 2 2 1 IncA protein Spc7 PF08317.6 KLO13955.1 - 0.007 15.0 10.1 0.013 14.2 7.0 1.4 1 0 0 1 1 1 1 Spc7 kinetochore protein CENP-Q PF13094.1 KLO13955.1 - 0.067 13.2 19.3 0.16 11.9 9.7 2.3 2 0 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit GAS PF13851.1 KLO13955.1 - 0.08 12.1 20.7 0.18 10.9 9.3 2.7 2 1 1 3 3 3 0 Growth-arrest specific micro-tubule binding EzrA PF06160.7 KLO13955.1 - 0.12 10.5 17.5 0.068 11.3 8.9 2.0 2 0 0 2 2 2 0 Septation ring formation regulator, EzrA DUF1664 PF07889.7 KLO13955.1 - 0.26 11.0 5.0 0.33 10.7 1.8 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Reo_sigmaC PF04582.7 KLO13955.1 - 0.32 10.1 2.7 0.41 9.7 1.9 1.3 1 0 0 1 1 1 0 Reovirus sigma C capsid protein KxDL PF10241.4 KLO13955.1 - 0.43 10.5 9.1 0.61 10.0 0.6 3.0 3 0 0 3 3 3 0 Uncharacterized conserved protein PFEMP PF03011.10 KLO13955.1 - 0.93 9.8 5.7 3.2 8.0 0.0 2.3 1 1 1 2 2 2 0 PFEMP DBL domain BEX PF04538.7 KLO13955.1 - 1 9.6 5.4 1.6 8.9 1.7 2.7 2 1 0 2 2 2 0 Brain expressed X-linked like family Seryl_tRNA_N PF02403.17 KLO13955.1 - 1.8 8.6 14.8 2.5 8.1 4.8 2.7 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain DUF972 PF06156.8 KLO13955.1 - 1.9 8.8 17.0 1.2 9.4 1.6 3.4 2 1 1 3 3 3 0 Protein of unknown function (DUF972) Flagellar_rod PF05149.7 KLO13955.1 - 2 7.5 15.9 0.27 10.3 7.9 1.9 2 0 0 2 2 2 0 Paraflagellar rod protein V_ATPase_I PF01496.14 KLO13955.1 - 3 5.5 9.8 5.6 4.6 6.8 1.6 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family Syntaxin-6_N PF09177.6 KLO13955.1 - 3 8.2 11.5 36 4.8 4.7 3.3 1 1 2 3 3 3 0 Syntaxin 6, N-terminal FlgN PF05130.7 KLO13955.1 - 3.2 7.9 22.7 2.9 8.1 10.3 2.8 2 1 1 3 3 3 0 FlgN protein DUF4094 PF13334.1 KLO13955.1 - 3.5 8.0 8.9 26 5.3 2.8 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4094) BLOC1_2 PF10046.4 KLO13955.1 - 4.8 7.3 11.4 0.5 10.5 1.5 3.1 2 1 1 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 AAA_13 PF13166.1 KLO13955.1 - 5.9 5.2 11.9 4 5.7 7.1 1.6 1 1 0 1 1 1 0 AAA domain CENP-H PF05837.7 KLO13955.1 - 8.7 6.5 16.2 3.6 7.8 1.0 2.7 3 0 0 3 3 3 0 Centromere protein H (CENP-H) RRM_1 PF00076.17 KLO13956.1 - 2.8e-54 180.6 0.0 1e-19 69.9 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KLO13956.1 - 2e-39 133.3 0.0 8.1e-13 48.1 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KLO13956.1 - 9.9e-26 89.3 0.0 1.4e-08 34.4 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Cas_Cas2CT1978 PF09707.5 KLO13956.1 - 9.7e-05 22.2 0.0 0.27 11.2 0.0 2.9 3 0 0 3 3 3 2 CRISPR-associated protein (Cas_Cas2CT1978) Nup35_RRM_2 PF14605.1 KLO13956.1 - 0.00012 21.7 0.0 2.1 8.2 0.0 3.4 3 0 0 3 3 3 3 Nup53/35/40-type RNA recognition motif Band_7 PF01145.20 KLO13957.1 - 1.3e-23 83.8 3.3 1.3e-23 83.7 1.5 1.6 1 1 1 2 2 2 1 SPFH domain / Band 7 family DUF2522 PF10747.4 KLO13957.1 - 0.11 12.5 0.2 0.2 11.6 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2522) Glyco_hydro_3 PF00933.16 KLO13958.1 - 1.2e-73 247.7 0.1 1.8e-73 247.1 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 KLO13958.1 - 2.4e-63 213.6 1.3 9.7e-63 211.7 0.6 2.2 2 1 0 2 2 2 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 KLO13958.1 - 1e-17 63.8 0.0 2.2e-17 62.7 0.0 1.6 1 0 0 1 1 1 1 Fibronectin type III-like domain CBM_1 PF00734.13 KLO13958.1 - 1e-11 44.2 6.9 2.7e-11 42.9 4.8 1.8 1 0 0 1 1 1 1 Fungal cellulose binding domain Phosphoprotein PF00922.12 KLO13958.1 - 0.9 8.7 9.6 1.8 7.7 6.6 1.5 1 0 0 1 1 1 0 Vesiculovirus phosphoprotein MSP1_C PF07462.6 KLO13958.1 - 6.5 5.0 7.4 9.6 4.4 5.1 1.1 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus Oxysterol_BP PF01237.13 KLO13959.1 - 1.1e-109 366.1 0.0 1.8e-109 365.5 0.0 1.3 1 0 0 1 1 1 1 Oxysterol-binding protein PH_8 PF15409.1 KLO13959.1 - 2e-19 69.4 0.2 5.4e-19 68.0 0.0 1.8 2 0 0 2 2 2 1 Pleckstrin homology domain PH PF00169.24 KLO13959.1 - 2.5e-06 27.6 0.4 8.4e-06 25.9 0.1 2.0 2 1 0 2 2 2 1 PH domain PH_11 PF15413.1 KLO13959.1 - 5.5e-06 26.6 0.8 0.00026 21.2 0.2 2.4 1 1 1 2 2 2 1 Pleckstrin homology domain Sec1 PF00995.18 KLO13960.1 - 2.5e-144 482.0 0.0 2.9e-144 481.7 0.0 1.0 1 0 0 1 1 1 1 Sec1 family MFS_1 PF07690.11 KLO13961.1 - 1.1e-22 80.2 20.7 3.7e-22 78.5 13.6 1.9 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF605 PF04652.11 KLO13962.1 - 1.5e-75 254.9 40.9 8e-74 249.3 28.3 2.6 1 1 0 1 1 1 1 Vta1 like DUF221 PF02714.10 KLO13963.1 - 2.3e-23 82.5 14.4 4.7e-23 81.5 10.0 1.5 1 0 0 1 1 1 1 Domain of unknown function DUF221 RSN1_TM PF13967.1 KLO13963.1 - 3.9e-07 29.7 0.7 3.9e-07 29.7 0.5 3.2 2 2 1 3 3 3 1 Late exocytosis, associated with Golgi transport DUF3779 PF12621.3 KLO13963.1 - 0.0017 18.2 0.0 0.0043 16.8 0.0 1.6 1 0 0 1 1 1 1 Phosphate metabolism protein DUF4463 PF14703.1 KLO13963.1 - 0.0047 17.4 0.1 0.018 15.5 0.0 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4463) Exonuc_X-T_C PF08411.5 KLO13963.1 - 0.099 11.6 0.1 0.57 9.1 0.0 1.9 2 0 0 2 2 2 0 Exonuclease C-terminal Septin PF00735.13 KLO13965.1 - 3.5e-107 357.6 0.0 5.9e-107 356.8 0.0 1.3 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.18 KLO13965.1 - 2.9e-06 27.2 0.0 6.9e-06 25.9 0.0 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.18 KLO13965.1 - 0.0023 17.7 4.0 0.18 11.6 0.0 2.9 2 1 1 3 3 3 2 Dynamin family DUF258 PF03193.11 KLO13965.1 - 0.0023 17.1 0.3 0.01 15.0 0.2 1.9 1 1 0 1 1 1 1 Protein of unknown function, DUF258 AIG1 PF04548.11 KLO13965.1 - 0.0031 16.6 0.0 0.0056 15.8 0.0 1.4 1 0 0 1 1 1 1 AIG1 family Miro PF08477.8 KLO13965.1 - 0.0057 17.1 0.4 0.027 14.9 0.0 2.2 2 0 0 2 2 2 1 Miro-like protein GTP_EFTU PF00009.22 KLO13965.1 - 0.0098 15.3 0.1 0.12 11.8 0.0 2.5 2 1 0 3 3 3 1 Elongation factor Tu GTP binding domain AAA_17 PF13207.1 KLO13965.1 - 0.01 16.6 1.4 0.042 14.6 0.9 2.4 1 1 0 1 1 1 1 AAA domain FtsK_SpoIIIE PF01580.13 KLO13965.1 - 0.02 14.3 0.1 0.048 13.1 0.1 1.6 1 0 0 1 1 1 0 FtsK/SpoIIIE family IIGP PF05049.8 KLO13965.1 - 0.045 12.5 0.6 0.082 11.7 0.1 1.6 2 0 0 2 2 2 0 Interferon-inducible GTPase (IIGP) AAA_22 PF13401.1 KLO13965.1 - 0.066 13.3 0.1 0.34 11.0 0.0 2.2 2 1 0 2 2 2 0 AAA domain MutS_V PF00488.16 KLO13966.1 - 1.9e-82 276.2 0.0 2.9e-82 275.5 0.0 1.3 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 KLO13966.1 - 1.4e-37 129.4 0.2 1.6e-36 126.0 0.0 2.6 2 1 0 2 2 2 1 MutS domain III MutS_I PF01624.15 KLO13966.1 - 4.1e-20 71.8 0.0 1.1e-19 70.5 0.0 1.7 1 0 0 1 1 1 1 MutS domain I MutS_II PF05188.12 KLO13966.1 - 8.7e-11 42.0 0.1 2.2e-10 40.7 0.0 1.7 1 0 0 1 1 1 1 MutS domain II MutS_IV PF05190.13 KLO13966.1 - 6.3e-05 23.0 0.0 0.00015 21.8 0.0 1.7 1 0 0 1 1 1 1 MutS family domain IV AAA_23 PF13476.1 KLO13966.1 - 0.013 15.8 0.8 0.1 12.9 0.0 2.6 3 0 0 3 3 3 0 AAA domain AAA_29 PF13555.1 KLO13966.1 - 0.017 14.6 0.1 0.043 13.3 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_14 PF13173.1 KLO13966.1 - 0.054 13.3 0.0 0.35 10.7 0.0 2.4 2 0 0 2 2 2 0 AAA domain Aconitase PF00330.15 KLO13967.1 - 3.4e-156 520.3 0.1 3e-155 517.2 0.0 2.0 1 1 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 KLO13967.1 - 2.9e-35 121.2 0.0 5e-35 120.4 0.0 1.4 1 0 0 1 1 1 1 Aconitase C-terminal domain Asn_synthase PF00733.16 KLO13968.1 - 5.4e-52 176.8 0.0 8.1e-52 176.2 0.0 1.2 1 0 0 1 1 1 1 Asparagine synthase GATase_7 PF13537.1 KLO13968.1 - 5.8e-06 26.0 0.0 1.4e-05 24.8 0.0 1.7 1 1 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.1 KLO13968.1 - 0.099 12.5 0.0 0.29 11.1 0.0 1.8 2 1 0 2 2 2 0 Glutamine amidotransferase domain 6PGD PF00393.14 KLO13969.1 - 1.1e-131 438.3 0.0 1.4e-131 438.0 0.0 1.1 1 0 0 1 1 1 1 6-phosphogluconate dehydrogenase, C-terminal domain NAD_binding_2 PF03446.10 KLO13969.1 - 6.9e-51 172.3 0.0 9.8e-51 171.8 0.0 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.12 KLO13969.1 - 0.001 19.4 0.1 0.0022 18.3 0.1 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_11 PF14833.1 KLO13969.1 - 0.089 12.8 0.0 0.25 11.4 0.0 1.8 1 0 0 1 1 1 0 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase 2-Hacid_dh_C PF02826.14 KLO13969.1 - 0.15 11.2 0.1 0.38 9.8 0.0 1.7 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Glycophorin_A PF01102.13 KLO13970.1 - 0.0014 18.4 0.0 0.0014 18.4 0.0 2.3 3 0 0 3 3 3 1 Glycophorin A Alpha_GJ PF03229.8 KLO13970.1 - 0.0035 17.6 1.0 0.0035 17.6 0.7 1.9 2 0 0 2 2 2 1 Alphavirus glycoprotein J IncA PF04156.9 KLO13970.1 - 0.027 14.0 1.9 0.028 14.0 0.2 1.7 2 0 0 2 2 2 0 IncA protein TMEM154 PF15102.1 KLO13971.1 - 7.4e-06 25.7 0.6 7.4e-06 25.7 0.4 1.7 2 0 0 2 2 2 1 TMEM154 protein family SKG6 PF08693.5 KLO13971.1 - 0.00023 20.4 4.9 0.00042 19.5 3.4 1.4 1 0 0 1 1 1 1 Transmembrane alpha-helix domain DUF912 PF06024.7 KLO13971.1 - 0.00026 20.9 0.0 0.00051 20.0 0.0 1.4 1 0 0 1 1 1 1 Nucleopolyhedrovirus protein of unknown function (DUF912) Protocadherin PF08374.6 KLO13971.1 - 0.00049 19.8 0.1 0.00086 19.0 0.1 1.4 1 0 0 1 1 1 1 Protocadherin Mid2 PF04478.7 KLO13971.1 - 0.00053 19.4 0.1 0.0012 18.2 0.1 1.5 1 0 0 1 1 1 1 Mid2 like cell wall stress sensor DUF1191 PF06697.7 KLO13971.1 - 0.0006 18.7 0.0 0.00088 18.1 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1191) Glycophorin_A PF01102.13 KLO13971.1 - 0.0012 18.5 1.3 0.0012 18.5 0.9 2.4 1 1 2 3 3 3 1 Glycophorin A Rifin_STEVOR PF02009.11 KLO13971.1 - 0.0017 18.0 0.0 0.0025 17.5 0.0 1.2 1 0 0 1 1 1 1 Rifin/stevor family Shisa PF13908.1 KLO13971.1 - 0.002 18.3 10.7 0.002 18.3 7.4 3.1 1 1 2 3 3 2 1 Wnt and FGF inhibitory regulator Herpes_gE PF02480.11 KLO13971.1 - 0.002 16.4 0.5 0.0029 15.9 0.3 1.2 1 0 0 1 1 1 1 Alphaherpesvirus glycoprotein E Rax2 PF12768.2 KLO13971.1 - 0.0027 16.9 0.1 0.0044 16.2 0.1 1.2 1 0 0 1 1 1 1 Cortical protein marker for cell polarity TMEM51 PF15345.1 KLO13971.1 - 0.0042 16.8 2.1 0.0062 16.2 1.2 1.5 1 1 0 1 1 1 1 Transmembrane protein 51 EphA2_TM PF14575.1 KLO13971.1 - 0.0046 17.3 0.2 0.0092 16.3 0.2 1.5 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain gpUL132 PF11359.3 KLO13971.1 - 0.006 15.9 3.9 0.006 15.9 2.7 1.6 1 1 0 1 1 1 1 Glycoprotein UL132 Podoplanin PF05808.6 KLO13971.1 - 0.012 15.1 1.9 0.024 14.2 1.3 1.5 1 0 0 1 1 1 0 Podoplanin L1R_F9L PF02442.12 KLO13971.1 - 0.1 12.0 1.4 0.17 11.3 1.0 1.2 1 0 0 1 1 1 0 Lipid membrane protein of large eukaryotic DNA viruses Syndecan PF01034.15 KLO13971.1 - 0.1 12.2 0.3 0.21 11.2 0.2 1.5 1 0 0 1 1 1 0 Syndecan domain Amnionless PF14828.1 KLO13971.1 - 0.16 10.4 0.0 0.22 9.9 0.0 1.1 1 0 0 1 1 1 0 Amnionless MIG-14_Wnt-bd PF06664.7 KLO13971.1 - 0.17 10.6 0.0 0.26 10.0 0.0 1.2 1 0 0 1 1 1 0 Wnt-binding factor required for Wnt secretion Plasmodium_Vir PF05795.6 KLO13971.1 - 0.2 10.7 0.1 0.32 10.1 0.0 1.3 1 0 0 1 1 1 0 Plasmodium vivax Vir protein TMEM154 PF15102.1 KLO13972.1 - 0.011 15.4 0.0 0.022 14.4 0.0 1.5 1 0 0 1 1 1 0 TMEM154 protein family Rax2 PF12768.2 KLO13972.1 - 0.013 14.7 0.1 0.02 14.1 0.1 1.2 1 0 0 1 1 1 0 Cortical protein marker for cell polarity Herpes_gE PF02480.11 KLO13972.1 - 0.024 12.9 0.1 0.036 12.3 0.0 1.2 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E DUF2207 PF09972.4 KLO13972.1 - 0.089 11.3 0.0 0.12 10.9 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Adeno_E3_CR2 PF02439.10 KLO13972.1 - 0.18 11.3 0.1 0.32 10.5 0.1 1.3 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 RAP1 PF07218.6 KLO13972.1 - 0.96 7.4 4.1 1.7 6.6 2.8 1.4 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Yippee-Mis18 PF03226.9 KLO13973.1 - 0.15 12.1 0.4 5 7.2 0.0 2.1 1 1 1 2 2 2 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly WD40 PF00400.27 KLO13974.1 - 2.2e-58 192.1 16.5 3.9e-11 42.3 0.0 6.7 7 0 0 7 7 7 6 WD domain, G-beta repeat TFIID_90kDa PF04494.10 KLO13974.1 - 1.3e-28 99.8 0.0 3.9e-28 98.3 0.0 1.7 2 0 0 2 2 2 1 WD40 associated region in TFIID subunit LisH PF08513.6 KLO13974.1 - 0.015 15.0 0.0 0.032 14.0 0.0 1.6 1 0 0 1 1 1 0 LisH eIF2A PF08662.6 KLO13974.1 - 0.077 12.6 0.0 1.7 8.3 0.0 2.3 1 1 1 2 2 2 0 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 KLO13974.1 - 7.3 4.5 10.6 8.6 4.3 0.4 4.3 3 1 2 5 5 5 0 Nucleoporin Nup120/160 NAD_binding_6 PF08030.7 KLO13975.1 - 3.4e-24 85.5 0.0 6.1e-24 84.6 0.0 1.4 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.7 KLO13975.1 - 3e-22 78.4 0.0 6.1e-22 77.4 0.0 1.5 1 0 0 1 1 1 1 FAD-binding domain Ferric_reduct PF01794.14 KLO13975.1 - 2.1e-15 56.9 10.3 2.1e-15 56.9 7.2 1.9 2 0 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_1 PF00175.16 KLO13975.1 - 0.00023 21.7 0.0 0.037 14.6 0.0 2.4 1 1 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.19 KLO13975.1 - 0.00077 19.5 0.0 0.0023 17.9 0.0 1.8 2 0 0 2 2 2 1 Oxidoreductase FAD-binding domain HORMA PF02301.13 KLO13976.1 - 9.8e-38 129.7 0.2 1.1e-37 129.5 0.1 1.0 1 0 0 1 1 1 1 HORMA domain ATG13 PF10033.4 KLO13976.1 - 0.023 14.1 0.4 0.1 12.0 0.3 1.9 1 1 0 1 1 1 0 Autophagy-related protein 13 BaxI_1 PF12811.2 KLO13976.1 - 0.086 11.9 0.1 0.13 11.4 0.0 1.2 1 0 0 1 1 1 0 Bax inhibitor 1 like Nucleoporin_C PF03177.9 KLO13977.1 - 3.9e-88 296.4 1.8 5.8e-88 295.8 1.2 1.2 1 0 0 1 1 1 1 Non-repetitive/WGA-negative nucleoporin C-terminal Nucleoporin_N PF08801.6 KLO13977.1 - 6.7e-63 212.8 0.0 1e-62 212.2 0.0 1.2 1 0 0 1 1 1 1 Nup133 N terminal like RINGv PF12906.2 KLO13979.1 - 1.1e-12 47.8 3.6 1.5e-12 47.3 2.5 1.2 1 0 0 1 1 1 1 RING-variant domain zf-RING_2 PF13639.1 KLO13979.1 - 0.00056 19.6 5.9 0.001 18.8 4.1 1.4 1 0 0 1 1 1 1 Ring finger domain PHD PF00628.24 KLO13979.1 - 0.18 11.5 3.7 0.3 10.7 2.6 1.4 1 0 0 1 1 1 0 PHD-finger DUF983 PF06170.7 KLO13979.1 - 0.25 11.4 4.7 7.2 6.8 0.1 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF983) Mito_carr PF00153.22 KLO13980.1 - 7.6e-51 169.7 3.9 1.7e-17 62.9 0.2 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein RNase_T PF00929.19 KLO13981.1 - 3.5e-07 30.6 0.0 4.1e-07 30.4 0.0 1.1 1 0 0 1 1 1 1 Exonuclease Cohesin_load PF10345.4 KLO13982.1 - 0.034 12.3 0.1 0.7 8.0 0.2 2.2 1 1 2 3 3 3 0 Cohesin loading factor Aldo_ket_red PF00248.16 KLO13983.1 - 2.7e-63 213.4 0.0 3.2e-63 213.2 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Sulfate_transp PF00916.15 KLO13987.1 - 1.3e-56 191.6 5.7 1.3e-56 191.6 4.0 2.0 3 0 0 3 3 3 1 Sulfate transporter family Sulfate_tra_GLY PF13792.1 KLO13987.1 - 9.4e-28 95.7 13.3 1.7e-27 94.9 4.4 3.1 2 0 0 2 2 2 1 Sulfate transporter N-terminal domain with GLY motif STAS PF01740.16 KLO13987.1 - 8.4e-18 63.8 0.0 1.6e-17 62.9 0.0 1.4 1 0 0 1 1 1 1 STAS domain STAS_2 PF13466.1 KLO13987.1 - 2.7e-06 27.2 0.0 8.3e-06 25.7 0.0 1.9 1 0 0 1 1 1 1 STAS domain AMP-binding PF00501.23 KLO13988.1 - 1.5e-40 138.8 0.0 2.2e-40 138.3 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme NAD_binding_4 PF07993.7 KLO13988.1 - 2.4e-35 121.6 0.0 4.3e-35 120.8 0.0 1.4 1 0 0 1 1 1 1 Male sterility protein Epimerase PF01370.16 KLO13988.1 - 3.5e-08 33.1 0.0 1.3e-07 31.2 0.0 2.0 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.20 KLO13988.1 - 0.00055 20.1 0.0 0.0013 18.8 0.0 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site adh_short PF00106.20 KLO13988.1 - 0.0086 16.0 0.4 0.059 13.2 0.1 2.5 2 1 0 2 2 2 1 short chain dehydrogenase bZIP_1 PF00170.16 KLO13989.1 - 4.2e-08 33.0 4.9 1.1e-07 31.6 3.3 1.8 1 1 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 KLO13989.1 - 1.3e-07 31.3 6.7 4.5e-05 23.1 4.6 2.4 1 1 0 1 1 1 1 Basic region leucine zipper Ndc1_Nup PF09531.5 KLO13989.1 - 2.2 6.5 4.9 4.5 5.5 3.4 1.4 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup zf-RING_UBOX PF13445.1 KLO13990.1 - 5.9e-07 29.1 4.4 0.00012 21.6 0.2 2.5 2 0 0 2 2 2 2 RING-type zinc-finger zf-Nse PF11789.3 KLO13990.1 - 0.00016 21.1 1.4 0.00039 19.8 0.8 1.8 1 1 1 2 2 2 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_2 PF13639.1 KLO13990.1 - 0.0013 18.5 2.5 0.0018 18.0 1.1 1.8 1 1 0 1 1 1 1 Ring finger domain U-box PF04564.10 KLO13990.1 - 0.0022 17.9 0.0 0.006 16.5 0.0 1.7 1 1 0 1 1 1 1 U-box domain zf-MIZ PF02891.15 KLO13990.1 - 0.0024 17.3 0.8 0.0043 16.5 0.5 1.4 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger UPF0547 PF10571.4 KLO13990.1 - 0.017 14.8 1.9 0.8 9.4 0.1 2.5 2 0 0 2 2 2 0 Uncharacterised protein family UPF0547 zf-C3HC4_2 PF13923.1 KLO13990.1 - 0.062 13.3 4.1 0.13 12.3 1.7 2.3 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) DUF1320 PF07030.7 KLO13990.1 - 0.065 12.9 1.5 0.078 12.7 0.4 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1320) GFO_IDH_MocA PF01408.17 KLO13990.1 - 0.073 13.5 0.0 0.094 13.2 0.0 1.2 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold Rtf2 PF04641.7 KLO13990.1 - 0.073 12.2 1.8 0.096 11.8 0.6 1.5 1 1 0 1 1 1 0 Rtf2 RING-finger DUF3584 PF12128.3 KLO13990.1 - 0.075 10.3 1.2 0.089 10.1 0.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) zf-C3HC4_4 PF15227.1 KLO13990.1 - 0.16 11.8 2.4 1.3 8.9 1.0 2.3 1 1 1 2 2 2 0 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.20 KLO13990.1 - 2.8 7.6 6.8 12 5.6 0.4 2.3 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KLO13990.1 - 3.8 7.2 6.7 63 3.3 4.6 2.5 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) COG5 PF10392.4 KLO13992.1 - 0.1 12.5 0.8 4.5 7.2 0.2 2.7 2 0 0 2 2 2 0 Golgi transport complex subunit 5 DUF848 PF05852.6 KLO13993.1 - 1.1 9.0 4.7 0.34 10.7 0.8 2.0 2 2 0 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) DIT1_PvcA PF05141.7 KLO13994.1 - 0.098 11.9 0.4 0.16 11.2 0.0 1.5 2 0 0 2 2 2 0 Pyoverdine/dityrosine biosynthesis protein SseC PF04888.7 KLO13994.1 - 0.49 9.6 4.6 1 8.6 3.2 1.5 1 1 0 1 1 1 0 Secretion system effector C (SseC) like family AF0941-like PF14591.1 KLO13995.1 - 0.035 14.1 0.6 0.26 11.3 0.0 2.4 2 1 0 2 2 2 0 AF0941-like DUF4208 PF13907.1 KLO13996.1 - 0.12 12.6 1.4 0.23 11.6 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4208) Aldo_ket_red PF00248.16 KLO13997.1 - 8.1e-75 251.2 0.0 9.2e-75 251.0 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family RhoGEF PF00621.15 KLO13998.1 - 1e-15 58.0 0.0 2.4e-09 37.3 0.0 2.6 2 0 0 2 2 2 2 RhoGEF domain CNH PF00780.17 KLO13998.1 - 9.7e-11 41.5 0.0 2.2e-10 40.4 0.0 1.5 1 0 0 1 1 1 1 CNH domain SUKH-3 PF14433.1 KLO13998.1 - 0.077 12.7 0.0 0.21 11.3 0.0 1.7 1 0 0 1 1 1 0 SUKH-3 immunity protein IRF PF00605.12 KLO13998.1 - 0.12 12.1 0.0 6.7 6.5 0.0 2.5 2 0 0 2 2 2 0 Interferon regulatory factor transcription factor p450 PF00067.17 KLO13999.1 - 9.7e-75 251.8 0.0 1.4e-74 251.3 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 IF4E PF01652.13 KLO14000.1 - 1.9e-48 164.1 0.0 2.7e-48 163.6 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E NolX PF05819.6 KLO14000.1 - 0.14 10.5 0.1 0.19 10.0 0.1 1.1 1 0 0 1 1 1 0 NolX protein Aldedh PF00171.17 KLO14001.1 - 3.7e-114 381.5 0.2 4.8e-114 381.2 0.2 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 KLO14001.1 - 9.6e-05 21.2 0.0 0.00017 20.4 0.0 1.5 2 0 0 2 2 2 1 Acyl-CoA reductase (LuxC) DUF1487 PF07368.6 KLO14001.1 - 0.12 11.5 0.2 0.49 9.5 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1487) Sin3_corepress PF08295.7 KLO14002.1 - 6.5e-38 128.5 0.0 1.5e-37 127.4 0.0 1.6 1 0 0 1 1 1 1 Sin3 family co-repressor PAH PF02671.16 KLO14002.1 - 2e-36 123.3 4.0 9e-16 57.2 0.0 3.7 3 0 0 3 3 3 3 Paired amphipathic helix repeat S1-P1_nuclease PF02265.11 KLO14003.1 - 1.4e-49 169.0 0.0 3.3e-44 151.4 0.0 2.1 2 0 0 2 2 2 2 S1/P1 Nuclease PRiA4_ORF3 PF07929.6 KLO14004.1 - 0.0058 16.0 0.1 0.0058 16.0 0.1 1.7 2 0 0 2 2 2 1 Plasmid pRiA4b ORF-3-like protein NmrA PF05368.8 KLO14005.1 - 7.5e-14 51.5 0.2 9.3e-14 51.2 0.1 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 KLO14005.1 - 0.00026 21.0 0.1 0.00034 20.6 0.1 1.2 1 0 0 1 1 1 1 NADH(P)-binding Saccharop_dh PF03435.13 KLO14005.1 - 0.003 16.5 0.0 0.004 16.1 0.0 1.1 1 0 0 1 1 1 1 Saccharopine dehydrogenase Peptidase_M24 PF00557.19 KLO14007.1 - 2.2e-46 158.0 0.0 3.3e-46 157.4 0.0 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 Creatinase_N PF01321.13 KLO14007.1 - 2.8e-31 108.7 0.1 1.4e-22 80.5 0.0 2.5 2 0 0 2 2 2 2 Creatinase/Prolidase N-terminal domain PIGA PF08288.7 KLO14008.1 - 4.4e-38 129.5 0.4 2.2e-37 127.3 0.2 2.2 2 0 0 2 2 2 1 PIGA (GPI anchor biosynthesis) Glycos_transf_1 PF00534.15 KLO14008.1 - 7.3e-26 90.6 0.0 1.1e-25 90.0 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.1 KLO14008.1 - 6.5e-16 58.5 1.4 1.2e-15 57.7 1.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.1 KLO14008.1 - 1.2e-14 54.7 0.3 1.9e-14 54.1 0.2 1.3 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_trans_1_4 PF13692.1 KLO14008.1 - 4.6e-12 46.2 0.0 1.3e-11 44.8 0.0 1.7 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_4_2 PF13477.1 KLO14008.1 - 0.00017 21.4 0.2 0.00044 20.0 0.0 1.7 2 0 0 2 2 2 1 Glycosyl transferase 4-like Glyco_trans_1_2 PF13524.1 KLO14008.1 - 0.0032 17.7 0.0 0.0065 16.7 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 AAA PF00004.24 KLO14009.1 - 6.3e-44 149.3 0.0 1.1e-43 148.5 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_2 PF07724.9 KLO14009.1 - 2e-07 31.0 0.0 3.9e-07 30.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.9 KLO14009.1 - 8.5e-07 28.7 0.0 5.1e-06 26.2 0.0 2.3 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 KLO14009.1 - 2.1e-06 27.8 0.0 9.8e-06 25.6 0.0 2.0 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 KLO14009.1 - 5.3e-06 26.6 0.2 0.00028 21.0 0.0 2.6 2 1 0 2 2 1 1 AAA domain AAA_17 PF13207.1 KLO14009.1 - 5.5e-05 23.9 0.0 0.00016 22.4 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 KLO14009.1 - 6.1e-05 22.6 0.1 0.00015 21.4 0.0 1.7 1 0 0 1 1 1 1 Part of AAA domain RuvB_N PF05496.7 KLO14009.1 - 9.1e-05 21.6 0.0 0.00017 20.7 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus IstB_IS21 PF01695.12 KLO14009.1 - 0.0003 20.2 0.0 0.00075 18.9 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein TIP49 PF06068.8 KLO14009.1 - 0.00089 18.0 0.0 0.0017 17.1 0.0 1.4 1 0 0 1 1 1 1 TIP49 C-terminus AAA_33 PF13671.1 KLO14009.1 - 0.0012 18.7 0.0 0.0031 17.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.1 KLO14009.1 - 0.0017 18.2 0.0 0.003 17.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 KLO14009.1 - 0.0019 17.3 0.0 0.0045 16.1 0.0 1.6 1 0 0 1 1 1 1 Zeta toxin PhoH PF02562.11 KLO14009.1 - 0.0027 16.9 0.0 0.063 12.5 0.0 2.2 2 0 0 2 2 2 1 PhoH-like protein AAA_28 PF13521.1 KLO14009.1 - 0.0034 17.3 0.0 0.0069 16.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_3 PF07726.6 KLO14009.1 - 0.0037 16.8 0.0 0.0076 15.8 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.1 KLO14009.1 - 0.0042 17.4 0.2 0.024 14.9 0.0 2.3 3 0 0 3 3 2 1 AAA domain Mg_chelatase PF01078.16 KLO14009.1 - 0.0062 15.7 0.0 0.013 14.6 0.0 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI KaiC PF06745.8 KLO14009.1 - 0.015 14.3 0.0 0.035 13.2 0.0 1.6 1 0 0 1 1 1 0 KaiC AAA_25 PF13481.1 KLO14009.1 - 0.018 14.4 0.1 0.09 12.1 0.0 1.9 1 1 1 2 2 2 0 AAA domain Sigma54_activat PF00158.21 KLO14009.1 - 0.018 14.5 0.2 0.084 12.3 0.0 2.1 2 1 0 2 2 2 0 Sigma-54 interaction domain DUF815 PF05673.8 KLO14009.1 - 0.021 13.7 0.0 0.035 13.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_24 PF13479.1 KLO14009.1 - 0.021 14.4 0.0 0.043 13.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain DUF2072 PF09845.4 KLO14009.1 - 0.031 14.2 0.2 0.064 13.1 0.1 1.5 1 0 0 1 1 1 0 Zn-ribbon containing protein (DUF2072) RNA_helicase PF00910.17 KLO14009.1 - 0.032 14.3 0.0 0.065 13.4 0.0 1.5 1 0 0 1 1 1 0 RNA helicase Sigma54_activ_2 PF14532.1 KLO14009.1 - 0.043 13.8 0.0 0.14 12.2 0.0 1.9 1 0 0 1 1 1 0 Sigma-54 interaction domain NACHT PF05729.7 KLO14009.1 - 0.044 13.4 0.0 0.56 9.8 0.0 2.2 1 1 0 2 2 2 0 NACHT domain Parvo_NS1 PF01057.12 KLO14009.1 - 0.047 12.5 0.0 0.088 11.6 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 DivIC PF04977.10 KLO14009.1 - 0.059 12.8 1.6 0.18 11.3 0.4 2.1 2 0 0 2 2 2 0 Septum formation initiator NB-ARC PF00931.17 KLO14009.1 - 0.094 11.5 0.0 0.17 10.6 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain AAA_11 PF13086.1 KLO14009.1 - 0.1 12.1 0.0 0.41 10.1 0.0 2.1 1 1 1 2 2 2 0 AAA domain G-alpha PF00503.15 KLO14011.1 - 2e-137 458.0 0.0 2.4e-137 457.8 0.0 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 KLO14011.1 - 6.5e-09 35.2 0.1 4e-05 22.9 0.0 2.4 2 0 0 2 2 2 2 ADP-ribosylation factor family AAA_29 PF13555.1 KLO14011.1 - 0.0013 18.1 0.0 0.003 17.0 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.1 KLO14011.1 - 0.008 16.1 0.0 0.057 13.3 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain DAP3 PF10236.4 KLO14011.1 - 0.054 12.4 0.7 0.2 10.5 0.4 1.8 1 1 1 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 ABC_tran PF00005.22 KLO14011.1 - 0.068 13.4 0.0 0.13 12.5 0.0 1.4 1 0 0 1 1 1 0 ABC transporter adh_short PF00106.20 KLO14012.1 - 2.3e-13 50.4 0.3 1.1e-12 48.2 0.1 1.9 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.1 KLO14012.1 - 1.5e-09 38.0 0.0 2.4e-06 27.5 0.0 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KLO14012.1 - 0.0018 18.0 0.1 0.0029 17.3 0.1 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 KLO14012.1 - 0.025 14.0 0.0 0.038 13.4 0.0 1.3 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 KLO14012.1 - 0.061 13.3 0.6 0.11 12.5 0.4 1.5 1 1 0 1 1 1 0 NADH(P)-binding AA_kinase PF00696.23 KLO14013.1 - 1.2e-37 129.7 0.0 3e-32 112.1 0.0 2.3 2 0 0 2 2 2 2 Amino acid kinase family ACT PF01842.20 KLO14013.1 - 2.6e-12 45.9 0.8 1.4e-07 30.8 0.0 2.9 3 0 0 3 3 3 2 ACT domain ACT_7 PF13840.1 KLO14013.1 - 4.2e-10 39.0 1.2 1.7e-08 33.8 0.1 2.6 2 0 0 2 2 2 1 ACT domain Hairpins PF04877.7 KLO14013.1 - 0.18 11.1 0.0 0.49 9.7 0.0 1.6 2 0 0 2 2 2 0 HrpZ Aminotran_1_2 PF00155.16 KLO14014.1 - 0.087 11.7 0.0 0.12 11.2 0.0 1.1 1 0 0 1 1 1 0 Aminotransferase class I and II FAM104 PF15434.1 KLO14014.1 - 6.1 7.0 11.9 0.3 11.2 4.3 1.8 2 0 0 2 2 2 0 Family 104 DUF605 PF04652.11 KLO14014.1 - 9.2 5.5 30.1 13 5.0 20.8 1.3 1 0 0 1 1 1 0 Vta1 like Methyltransf_16 PF10294.4 KLO14017.1 - 2.1e-06 27.2 0.1 0.0008 18.9 0.0 2.2 2 0 0 2 2 2 2 Putative methyltransferase Methyltransf_31 PF13847.1 KLO14017.1 - 0.00058 19.4 0.0 0.16 11.5 0.0 2.3 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_12 PF08242.7 KLO14017.1 - 0.0016 18.9 0.2 0.21 12.0 0.0 2.6 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 KLO14017.1 - 0.016 14.9 0.0 0.026 14.2 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Metallophos PF00149.23 KLO14018.1 - 2.7e-42 144.4 0.3 3.8e-42 143.9 0.2 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase UNC-50 PF05216.8 KLO14019.1 - 2.8e-83 278.6 13.9 3.2e-83 278.5 9.7 1.0 1 0 0 1 1 1 1 UNC-50 family zf-MYND PF01753.13 KLO14022.1 - 2.7e-10 39.9 13.1 4.8e-10 39.1 9.1 1.4 1 0 0 1 1 1 1 MYND finger Tnp_zf-ribbon_2 PF13842.1 KLO14022.1 - 0.64 10.4 5.3 1.9 8.9 3.7 1.8 1 0 0 1 1 1 0 DDE_Tnp_1-like zinc-ribbon adh_short PF00106.20 KLO14023.1 - 2.5e-13 50.2 0.0 4.4e-13 49.4 0.0 1.5 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KLO14023.1 - 0.00018 21.2 0.1 0.001 18.7 0.0 1.9 2 0 0 2 2 2 1 KR domain adh_short_C2 PF13561.1 KLO14023.1 - 0.0041 16.9 0.0 0.0055 16.4 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase HMA PF00403.21 KLO14023.1 - 0.058 13.5 0.0 0.16 12.1 0.0 1.7 1 0 0 1 1 1 0 Heavy-metal-associated domain CNH PF00780.17 KLO14025.1 - 0.013 14.8 0.0 0.016 14.6 0.0 1.2 1 0 0 1 1 1 0 CNH domain HNOB PF07700.10 KLO14025.1 - 0.083 12.4 0.1 0.17 11.3 0.1 1.5 1 0 0 1 1 1 0 Heme NO binding NfeD PF01957.13 KLO14028.1 - 0.0058 16.7 1.4 0.33 11.0 0.0 2.3 2 0 0 2 2 2 2 NfeD-like C-terminal, partner-binding DUF4345 PF14248.1 KLO14028.1 - 0.026 13.9 1.5 0.055 12.9 1.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4345) DUF4231 PF14015.1 KLO14028.1 - 0.039 13.9 7.1 2.1 8.3 0.6 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF4231) Ion_trans_2 PF07885.11 KLO14029.1 - 1.5e-30 104.7 31.0 6.1e-18 64.3 5.2 3.3 3 0 0 3 3 3 2 Ion channel Sigma70_ner PF04546.8 KLO14029.1 - 0.68 9.5 5.8 1.6 8.3 4.0 1.6 1 0 0 1 1 1 0 Sigma-70, non-essential region FAD_binding_4 PF01565.18 KLO14030.1 - 7.1e-20 70.8 0.5 1.3e-19 70.0 0.4 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 KLO14030.1 - 1.3e-09 37.8 0.2 2.7e-09 36.7 0.2 1.6 1 0 0 1 1 1 1 Berberine and berberine like Pribosyltran PF00156.22 KLO14031.1 - 1.3e-15 57.2 0.1 2.4e-15 56.3 0.0 1.5 1 0 0 1 1 1 1 Phosphoribosyl transferase domain DER1 PF04511.10 KLO14032.1 - 2.3e-30 105.6 9.8 2.8e-30 105.3 6.8 1.0 1 0 0 1 1 1 1 Der1-like family CorA PF01544.13 KLO14034.1 - 1.8e-10 40.3 2.3 2.9e-10 39.6 1.6 1.3 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein Syntaxin PF00804.20 KLO14034.1 - 0.036 14.2 0.2 0.13 12.4 0.0 2.0 2 0 0 2 2 2 0 Syntaxin DUF2800 PF10926.3 KLO14034.1 - 0.13 11.4 0.2 0.18 10.8 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2800) DUF1469 PF07332.6 KLO14034.1 - 0.86 9.3 6.5 2.3 7.9 4.5 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1469) Mg_trans_NIPA PF05653.9 KLO14036.1 - 8.2e-105 350.0 14.6 1e-104 349.7 10.1 1.0 1 0 0 1 1 1 1 Magnesium transporter NIPA EmrE PF13536.1 KLO14036.1 - 9.7e-07 28.9 0.3 9.7e-07 28.9 0.2 3.4 2 1 1 3 3 3 1 Multidrug resistance efflux transporter AAA_12 PF13087.1 KLO14037.1 - 5.4e-44 149.9 0.0 9.1e-44 149.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 KLO14037.1 - 6.3e-30 104.4 0.0 8.3e-14 51.7 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.1 KLO14037.1 - 1.2e-10 40.9 0.0 3.2e-10 39.6 0.0 1.7 1 0 0 1 1 1 1 Part of AAA domain AAA_30 PF13604.1 KLO14037.1 - 1.4e-10 41.0 0.0 1.1e-09 38.1 0.0 2.3 2 1 0 2 2 2 1 AAA domain zf-met PF12874.2 KLO14037.1 - 9.9e-07 28.7 14.1 7.9e-05 22.7 0.2 4.1 3 1 0 3 3 2 2 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 KLO14037.1 - 0.00022 21.2 8.4 0.00027 20.9 0.1 3.3 3 0 0 3 3 3 1 Zinc-finger double-stranded RNA-binding AAA_22 PF13401.1 KLO14037.1 - 0.0053 16.8 0.0 0.017 15.2 0.0 1.9 1 1 0 1 1 1 1 AAA domain UvrD-helicase PF00580.16 KLO14037.1 - 0.0079 15.5 0.0 0.072 12.3 0.0 2.1 2 0 0 2 2 2 1 UvrD/REP helicase N-terminal domain DUF3505 PF12013.3 KLO14037.1 - 0.013 15.7 1.4 3.8 7.7 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3505) zf-C2H2_2 PF12756.2 KLO14037.1 - 0.025 14.6 4.7 0.2 11.8 0.5 3.1 2 1 1 3 3 3 0 C2H2 type zinc-finger (2 copies) DUF2075 PF09848.4 KLO14037.1 - 0.029 13.3 0.0 0.067 12.1 0.0 1.6 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA PF00004.24 KLO14037.1 - 0.062 13.5 0.0 0.19 11.9 0.0 1.9 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) zf-C2H2 PF00096.21 KLO14037.1 - 0.064 13.6 0.3 0.064 13.6 0.2 3.0 4 0 0 4 4 2 0 Zinc finger, C2H2 type AAA_25 PF13481.1 KLO14037.1 - 0.066 12.6 0.1 4.6 6.6 0.0 2.5 1 1 1 2 2 2 0 AAA domain UvrD_C PF13361.1 KLO14037.1 - 0.1 12.0 0.0 7.2 5.9 0.0 2.2 2 0 0 2 2 2 0 UvrD-like helicase C-terminal domain AAA_16 PF13191.1 KLO14037.1 - 0.12 12.3 0.0 0.29 11.1 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain zf-C2H2_6 PF13912.1 KLO14037.1 - 0.12 12.3 1.1 0.33 10.9 0.0 2.3 2 0 0 2 2 2 0 C2H2-type zinc finger AAA_10 PF12846.2 KLO14037.1 - 0.14 11.5 0.0 0.57 9.5 0.0 1.9 2 0 0 2 2 2 0 AAA-like domain Mg_chelatase PF01078.16 KLO14037.1 - 0.15 11.1 0.0 0.33 10.0 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI ChAPs PF09295.5 KLO14038.1 - 2.3e-147 490.8 0.0 1.4e-145 485.0 0.0 2.1 2 0 0 2 2 2 1 ChAPs (Chs5p-Arf1p-binding proteins) TPR_19 PF14559.1 KLO14038.1 - 6.8e-07 29.5 3.0 0.0003 21.0 0.0 4.1 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_11 PF13414.1 KLO14038.1 - 1.6e-05 24.4 4.1 0.0032 17.0 0.0 3.9 3 1 0 3 3 3 1 TPR repeat TPR_14 PF13428.1 KLO14038.1 - 0.00021 21.6 7.4 15 6.5 0.0 7.4 5 2 4 9 9 7 0 Tetratricopeptide repeat TPR_8 PF13181.1 KLO14038.1 - 0.002 17.7 0.1 0.21 11.4 0.1 3.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.1 KLO14038.1 - 0.0029 17.5 6.8 0.34 10.8 0.0 4.7 4 1 0 4 4 4 1 Tetratricopeptide repeat TPR_6 PF13174.1 KLO14038.1 - 0.015 15.6 3.1 2.5 8.7 0.0 4.5 6 0 0 6 6 5 0 Tetratricopeptide repeat TPR_15 PF13429.1 KLO14038.1 - 0.02 13.9 4.2 1.4 7.8 0.4 2.8 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_1 PF00515.23 KLO14038.1 - 0.028 14.0 0.4 11 5.8 0.1 4.0 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.1 KLO14038.1 - 0.11 13.2 6.6 22 5.8 0.0 4.7 4 1 0 4 4 4 0 Tetratricopeptide repeat TPR_2 PF07719.12 KLO14038.1 - 0.12 12.3 15.4 1.6 8.8 0.2 6.2 6 1 1 7 7 6 0 Tetratricopeptide repeat ANAPC15 PF15243.1 KLO14038.1 - 0.5 10.4 6.0 1.6 8.8 4.1 1.8 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 15 DUF2046 PF09755.4 KLO14039.1 - 6.3e-09 35.1 7.9 8.9e-09 34.6 3.2 2.0 2 0 0 2 2 2 1 Uncharacterized conserved protein H4 (DUF2046) PAPA-1 PF04795.7 KLO14039.1 - 0.089 13.5 0.3 0.089 13.5 0.2 1.8 2 0 0 2 2 2 0 PAPA-1-like conserved region DUF4603 PF15376.1 KLO14039.1 - 2.3 5.3 4.2 3 4.9 2.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4603) HSP20 PF00011.16 KLO14040.1 - 3.1e-12 46.2 1.3 6.9e-12 45.1 0.0 2.1 3 0 0 3 3 3 1 Hsp20/alpha crystallin family PAT1 PF09770.4 KLO14040.1 - 2.3 6.3 28.2 2.8 6.0 19.6 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Med15 PF09606.5 KLO14040.1 - 6.7 4.7 35.9 8.8 4.3 24.9 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal RhoGEF PF00621.15 KLO14042.1 - 7.8e-08 32.4 0.3 1.5e-07 31.4 0.2 1.4 1 0 0 1 1 1 1 RhoGEF domain CNH PF00780.17 KLO14043.1 - 1e-13 51.3 0.0 1.1e-13 51.2 0.0 1.1 1 0 0 1 1 1 1 CNH domain TPR_12 PF13424.1 KLO14044.1 - 1.6e-16 60.0 8.4 4.3e-05 23.3 0.0 4.7 3 1 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.12 KLO14044.1 - 1.1e-10 40.5 13.5 0.0044 16.8 0.0 7.1 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_11 PF13414.1 KLO14044.1 - 8.2e-08 31.7 12.2 0.25 11.0 1.0 5.3 5 1 1 6 6 4 4 TPR repeat AAA_22 PF13401.1 KLO14044.1 - 1e-07 32.1 0.0 2.8e-07 30.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain NB-ARC PF00931.17 KLO14044.1 - 2.9e-07 29.6 0.0 5.5e-07 28.7 0.0 1.4 1 0 0 1 1 1 1 NB-ARC domain NACHT PF05729.7 KLO14044.1 - 9.3e-07 28.6 0.0 1.9e-06 27.6 0.0 1.5 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 KLO14044.1 - 1.1e-05 25.5 0.2 0.0002 21.4 0.1 3.2 2 1 0 2 2 2 1 AAA ATPase domain TPR_7 PF13176.1 KLO14044.1 - 1.2e-05 24.6 4.3 0.015 15.0 0.1 4.9 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_8 PF13181.1 KLO14044.1 - 2.1e-05 23.9 6.5 0.66 9.8 0.0 5.8 7 0 0 7 7 5 1 Tetratricopeptide repeat AAA PF00004.24 KLO14044.1 - 4.1e-05 23.8 0.0 9.7e-05 22.5 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) TPR_14 PF13428.1 KLO14044.1 - 6.2e-05 23.2 13.9 3.5 8.5 0.0 6.1 4 1 2 6 6 5 2 Tetratricopeptide repeat TPR_1 PF00515.23 KLO14044.1 - 0.00049 19.5 10.9 0.003 17.1 0.0 5.5 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_19 PF14559.1 KLO14044.1 - 0.0022 18.2 4.9 1.3 9.3 0.0 4.2 2 1 1 3 3 3 1 Tetratricopeptide repeat Arch_ATPase PF01637.13 KLO14044.1 - 0.013 15.2 0.0 0.028 14.1 0.0 1.6 1 0 0 1 1 1 0 Archaeal ATPase TPR_4 PF07721.9 KLO14044.1 - 0.029 14.8 16.4 0.91 10.1 2.3 5.8 6 0 0 6 6 5 0 Tetratricopeptide repeat DUF258 PF03193.11 KLO14044.1 - 0.05 12.7 0.0 0.1 11.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 TPR_16 PF13432.1 KLO14044.1 - 0.068 13.8 24.2 0.37 11.5 3.9 5.5 3 1 3 6 6 6 0 Tetratricopeptide repeat Sigma54_activat PF00158.21 KLO14044.1 - 0.07 12.6 0.0 0.13 11.6 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain RuvB_N PF05496.7 KLO14044.1 - 0.071 12.1 0.0 0.14 11.1 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus IstB_IS21 PF01695.12 KLO14044.1 - 0.078 12.3 0.0 0.21 10.9 0.0 1.7 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_14 PF13173.1 KLO14044.1 - 0.14 12.0 0.0 0.34 10.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain TPR_10 PF13374.1 KLO14044.1 - 0.16 11.9 7.9 1.8 8.6 0.0 4.4 5 0 0 5 5 4 0 Tetratricopeptide repeat RNA_pol_L_2 PF13656.1 KLO14045.1 - 4.7e-25 86.8 0.0 5.9e-25 86.5 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.19 KLO14045.1 - 1.1e-08 34.0 0.0 1.4e-08 33.7 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain DDE_1 PF03184.14 KLO14049.1 - 9.7e-26 90.2 0.0 1.2e-25 89.9 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_3 PF13358.1 KLO14049.1 - 0.00015 21.5 0.0 0.00021 21.0 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.11 KLO14050.1 - 7.3e-06 25.7 0.1 8.7e-06 25.4 0.0 1.1 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain BDHCT PF08072.6 KLO14050.1 - 0.0072 16.4 0.2 0.01 15.9 0.1 1.3 1 0 0 1 1 1 1 BDHCT (NUC031) domain Tet_JBP PF12851.2 KLO14059.1 - 1e-07 31.4 0.0 1.3e-07 31.0 0.0 1.1 1 0 0 1 1 1 1 Oxygenase domain of the 2OGFeDO superfamily F-box-like PF12937.2 KLO14062.1 - 1.6e-05 24.5 0.6 1.6e-05 24.5 0.4 2.0 2 0 0 2 2 2 1 F-box-like F-box-like_2 PF13013.1 KLO14062.1 - 0.06 13.0 0.2 0.17 11.5 0.1 1.7 1 0 0 1 1 1 0 F-box-like domain F-box-like PF12937.2 KLO14063.1 - 1.9e-06 27.5 0.7 1.7e-05 24.4 0.2 2.8 2 0 0 2 2 2 1 F-box-like F-box-like_2 PF13013.1 KLO14063.1 - 1.4e-05 24.7 1.1 2e-05 24.2 0.1 1.8 2 0 0 2 2 2 1 F-box-like domain F-box-like PF12937.2 KLO14064.1 - 0.00073 19.2 2.6 0.0025 17.5 1.8 2.0 1 1 0 1 1 1 1 F-box-like F-box PF00646.28 KLO14064.1 - 0.0065 16.1 3.8 2 8.1 2.5 3.6 2 1 1 3 3 3 2 F-box domain Phage_antitermQ PF06530.7 KLO14064.1 - 0.14 11.6 0.1 0.33 10.5 0.1 1.5 1 0 0 1 1 1 0 Phage antitermination protein Q BioW PF03744.8 KLO14067.1 - 0.095 12.1 0.0 0.12 11.7 0.0 1.1 1 0 0 1 1 1 0 6-carboxyhexanoate--CoA ligase PBP1_TM PF14812.1 KLO14071.1 - 0.28 11.5 5.0 0.77 10.0 0.1 3.5 3 0 0 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal CENP-B_dimeris PF09026.5 KLO14071.1 - 0.82 9.9 5.2 0.24 11.6 0.2 2.4 2 0 0 2 2 2 0 Centromere protein B dimerisation domain DUF4611 PF15387.1 KLO14071.1 - 1.3 9.1 6.8 0.26 11.4 1.5 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) F-box-like PF12937.2 KLO14074.1 - 8.7e-06 25.3 0.1 3.3e-05 23.5 0.0 2.0 1 1 0 1 1 1 1 F-box-like F-box PF00646.28 KLO14074.1 - 0.021 14.4 3.3 0.17 11.6 1.2 2.9 2 0 0 2 2 2 0 F-box domain zf-U11-48K PF05253.7 KLO14074.1 - 0.23 11.1 2.2 3 7.6 0.8 3.0 3 0 0 3 3 3 0 U11-48K-like CHHC zinc finger F-box-like PF12937.2 KLO14076.1 - 1.2e-07 31.2 0.6 3.9e-07 29.6 0.2 2.1 2 0 0 2 2 2 1 F-box-like F-box-like_2 PF13013.1 KLO14076.1 - 0.0032 17.1 0.2 0.011 15.4 0.1 1.9 1 1 0 1 1 1 1 F-box-like domain F-box PF00646.28 KLO14076.1 - 2.3 7.9 9.9 16 5.3 0.0 4.2 2 1 1 3 3 3 0 F-box domain F-box-like PF12937.2 KLO14077.1 - 0.00055 19.6 0.9 0.003 17.2 0.2 2.6 2 0 0 2 2 2 1 F-box-like F-box-like_2 PF13013.1 KLO14077.1 - 0.00064 19.4 0.2 0.0016 18.1 0.1 1.7 1 0 0 1 1 1 1 F-box-like domain DUF1151 PF06625.6 KLO14077.1 - 0.036 13.7 1.5 0.076 12.7 1.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1151) RRF PF01765.14 KLO14077.1 - 0.08 12.4 1.4 0.16 11.4 1.0 1.4 1 0 0 1 1 1 0 Ribosome recycling factor F-box-like PF12937.2 KLO14078.1 - 7.4e-06 25.5 2.2 9.9e-06 25.1 0.4 2.1 2 0 0 2 2 2 1 F-box-like Amidohydro_2 PF04909.9 KLO14080.1 - 0.016 14.8 0.1 0.017 14.6 0.1 1.1 1 0 0 1 1 1 0 Amidohydrolase F-box-like PF12937.2 KLO14081.1 - 2e-08 33.8 3.7 4.7e-07 29.4 0.4 2.7 2 0 0 2 2 2 2 F-box-like LRR_8 PF13855.1 KLO14081.1 - 0.23 11.2 1.2 12 5.7 0.0 3.5 3 0 0 3 3 3 0 Leucine rich repeat F-box-like PF12937.2 KLO14082.1 - 8.5e-05 22.1 0.5 0.00026 20.6 0.3 1.9 1 0 0 1 1 1 1 F-box-like F-box-like PF12937.2 KLO14083.1 - 3.4e-07 29.8 0.6 9.4e-07 28.4 0.0 2.1 2 0 0 2 2 2 1 F-box-like F-box-like PF12937.2 KLO14084.1 - 1.9e-07 30.7 0.3 6.8e-07 28.9 0.0 2.2 2 0 0 2 2 2 1 F-box-like DUF2187 PF09953.4 KLO14084.1 - 0.14 11.8 0.0 0.29 10.9 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2187) F-box PF00646.28 KLO14084.1 - 0.61 9.8 4.5 0.28 10.8 0.4 2.5 2 1 0 2 2 2 0 F-box domain F-box-like PF12937.2 KLO14085.1 - 0.02 14.6 0.6 0.042 13.5 0.4 1.6 1 0 0 1 1 1 0 F-box-like Keratin PF02422.11 KLO14085.1 - 0.098 12.6 0.1 0.12 12.3 0.1 1.3 1 1 0 1 1 1 0 Keratin F-box-like PF12937.2 KLO14086.1 - 1.4e-05 24.6 1.3 2.1e-05 24.1 0.0 2.0 2 0 0 2 2 2 1 F-box-like F-box-like PF12937.2 KLO14087.1 - 1e-07 31.5 0.2 3.8e-07 29.7 0.0 2.2 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 KLO14087.1 - 0.14 11.8 4.2 4.6 7.0 2.7 3.2 2 1 0 2 2 2 0 F-box domain Erf4 PF10256.4 KLO14088.1 - 0.0002 21.1 0.0 0.00042 20.1 0.0 1.6 2 0 0 2 2 2 1 Golgin subfamily A member 7/ERF4 family Erf4 PF10256.4 KLO14089.1 - 3.9e-05 23.5 0.0 5.4e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 Golgin subfamily A member 7/ERF4 family DUF4646 PF15496.1 KLO14089.1 - 0.051 13.6 0.0 0.1 12.6 0.0 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4646) adh_short_C2 PF13561.1 KLO14091.1 - 4.9e-20 72.3 0.0 5.6e-20 72.1 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 KLO14091.1 - 3.6e-12 46.5 0.1 5.7e-12 45.8 0.1 1.4 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KLO14091.1 - 2.7e-07 30.4 0.1 4.8e-07 29.6 0.1 1.3 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.10 KLO14091.1 - 0.071 11.9 0.1 0.092 11.6 0.0 1.1 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein GRDA PF04723.9 KLO14091.1 - 0.076 12.7 0.0 0.18 11.5 0.0 1.6 1 0 0 1 1 1 0 Glycine reductase complex selenoprotein A zf-RVT PF13966.1 KLO14092.1 - 0.0011 19.2 0.1 0.0025 18.0 0.1 1.7 1 1 1 2 2 2 1 zinc-binding in reverse transcriptase F-box-like PF12937.2 KLO14096.1 - 5.8e-07 29.1 0.2 5.4e-06 26.0 0.0 2.7 2 0 0 2 2 2 1 F-box-like LRR_4 PF12799.2 KLO14096.1 - 0.12 12.0 2.7 3.4 7.3 0.6 3.3 2 1 1 3 3 3 0 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KLO14096.1 - 9.2 6.1 8.6 0.67 9.7 0.3 3.3 5 0 0 5 5 5 0 Leucine rich repeat F-box-like PF12937.2 KLO14097.1 - 5.7e-07 29.1 2.8 2.3e-05 24.0 0.1 2.6 2 0 0 2 2 2 2 F-box-like LRR_4 PF12799.2 KLO14097.1 - 0.11 12.1 0.2 0.9 9.2 0.1 2.6 3 0 0 3 3 3 0 Leucine Rich repeats (2 copies) F-box-like PF12937.2 KLO14098.1 - 5.4e-10 38.8 2.8 2.7e-09 36.6 0.1 2.6 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 KLO14098.1 - 0.00021 20.8 0.0 0.00089 18.8 0.0 2.2 1 0 0 1 1 1 1 F-box domain LRR_8 PF13855.1 KLO14098.1 - 0.038 13.7 3.0 1.4 8.6 0.1 4.3 6 1 0 6 6 6 0 Leucine rich repeat HMG_box PF00505.14 KLO14100.1 - 1.2e-15 57.4 2.8 2e-15 56.7 1.9 1.4 1 1 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 KLO14100.1 - 8.3e-07 29.2 0.1 1.2e-06 28.7 0.1 1.3 1 0 0 1 1 1 1 HMG-box domain STE3 PF02076.10 KLO14101.1 - 3.7e-66 223.1 13.3 4.7e-66 222.7 9.2 1.1 1 0 0 1 1 1 1 Pheromone A receptor Ninjurin PF04923.7 KLO14101.1 - 0.046 13.4 0.7 0.11 12.1 0.3 1.8 1 1 0 1 1 1 0 Ninjurin F-box-like PF12937.2 KLO14102.1 - 0.00011 21.9 1.0 0.00033 20.3 0.7 1.8 1 1 0 1 1 1 1 F-box-like F-box PF00646.28 KLO14102.1 - 0.028 14.0 4.4 0.32 10.7 3.0 2.4 1 1 0 1 1 1 0 F-box domain F-box-like PF12937.2 KLO14103.1 - 3.4e-05 23.4 0.5 8.7e-05 22.1 0.3 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KLO14103.1 - 0.002 17.7 1.1 0.0066 16.0 0.7 2.0 1 1 0 1 1 1 1 F-box domain LRR_4 PF12799.2 KLO14103.1 - 3.4 7.3 5.4 2.4 7.8 0.0 3.4 4 0 0 4 4 4 0 Leucine Rich repeats (2 copies) NAC PF01849.13 KLO14104.1 - 3.9e-20 71.1 0.0 7.2e-20 70.2 0.0 1.5 1 0 0 1 1 1 1 NAC domain FtsH_ext PF06480.10 KLO14104.1 - 0.13 12.4 0.0 0.26 11.4 0.0 1.5 1 0 0 1 1 1 0 FtsH Extracellular Cofilin_ADF PF00241.15 KLO14105.1 - 2.8e-17 62.7 0.2 3.2e-17 62.5 0.1 1.0 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein F-box-like PF12937.2 KLO14106.1 - 2.9e-05 23.6 1.3 6.4e-05 22.6 0.2 2.1 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 KLO14106.1 - 0.001 18.6 1.1 0.0053 16.3 0.8 2.2 1 1 0 1 1 1 1 F-box domain Neugrin PF06413.6 KLO14107.1 - 2.9e-14 53.4 1.0 3.5e-14 53.1 0.4 1.3 1 1 0 1 1 1 1 Neugrin MRP-L20 PF12824.2 KLO14107.1 - 1.2e-07 31.8 2.1 1.3e-07 31.7 1.0 1.4 1 1 0 1 1 1 1 Mitochondrial ribosomal protein subunit L20 FeoC PF09012.5 KLO14107.1 - 0.029 14.0 0.2 1.3 8.7 0.0 2.3 2 1 0 2 2 2 0 FeoC like transcriptional regulator MarR_2 PF12802.2 KLO14107.1 - 0.05 13.2 0.0 0.11 12.2 0.0 1.6 1 0 0 1 1 1 0 MarR family UPF0122 PF04297.9 KLO14107.1 - 0.11 12.4 0.1 0.16 12.0 0.1 1.2 1 0 0 1 1 1 0 Putative helix-turn-helix protein, YlxM / p13 like F-box-like PF12937.2 KLO14108.1 - 1.2e-15 56.9 5.0 1.7e-07 30.8 0.4 2.9 2 0 0 2 2 2 2 F-box-like F-box PF00646.28 KLO14108.1 - 5.2e-06 25.9 14.0 0.0052 16.3 0.2 4.0 3 1 0 3 3 3 2 F-box domain Acetyltransf_1 PF00583.19 KLO14109.1 - 1.7e-13 50.3 0.0 3e-13 49.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 KLO14109.1 - 4.8e-06 26.6 0.0 7.9e-06 25.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 KLO14109.1 - 1.5e-05 25.0 0.0 2.1e-05 24.6 0.0 1.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 KLO14109.1 - 0.00012 21.7 0.0 0.00022 20.9 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_CG PF14542.1 KLO14109.1 - 0.0005 19.8 0.0 0.001 18.8 0.0 1.5 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_3 PF13302.1 KLO14109.1 - 0.00065 19.8 0.0 0.00086 19.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 KLO14109.1 - 0.025 14.4 0.0 0.057 13.2 0.0 1.7 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain F-box-like PF12937.2 KLO14110.1 - 1e-05 25.1 0.4 4.6e-05 23.0 0.0 2.3 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 KLO14110.1 - 0.9 9.2 4.9 1 9.0 0.9 3.0 2 1 0 2 2 2 0 F-box domain XPG_I PF00867.13 KLO14111.1 - 1.6e-16 60.0 0.0 3.5e-16 59.0 0.0 1.6 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.12 KLO14111.1 - 1.3e-07 31.7 0.0 2.9e-07 30.6 0.0 1.6 1 0 0 1 1 1 1 XPG N-terminal domain DUF2893 PF11459.3 KLO14111.1 - 0.034 13.9 0.3 0.088 12.6 0.2 1.7 1 0 0 1 1 1 0 Protein of unknwon function (DUF2893) DUF706 PF05153.10 KLO14112.1 - 7.3e-132 438.2 2.8 8.8e-132 438.0 1.9 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF706) HD PF01966.17 KLO14112.1 - 0.0013 18.6 0.3 0.12 12.3 0.0 2.9 2 1 1 3 3 3 1 HD domain DNA_pack_N PF02500.10 KLO14112.1 - 0.1 12.1 0.2 0.17 11.3 0.1 1.3 1 0 0 1 1 1 0 Probable DNA packing protein, N-terminus Transket_pyr PF02779.19 KLO14113.1 - 5.4e-61 205.1 0.0 8.1e-61 204.5 0.0 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain E1_dh PF00676.15 KLO14113.1 - 2.9e-38 131.2 0.0 4.8e-38 130.5 0.0 1.3 1 0 0 1 1 1 1 Dehydrogenase E1 component Pkinase PF00069.20 KLO14114.1 - 3e-40 138.0 0.0 5.7e-40 137.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KLO14114.1 - 2.5e-37 128.3 0.0 4.1e-37 127.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KLO14114.1 - 0.00049 19.1 0.0 0.0011 18.0 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Pox_ser-thr_kin PF05445.6 KLO14114.1 - 0.28 9.9 0.0 0.48 9.1 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase DEAD PF00270.24 KLO14115.1 - 4.1e-18 65.4 0.0 8e-18 64.4 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.10 KLO14115.1 - 5.5e-08 32.8 0.0 7.5e-07 29.1 0.0 2.9 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit Helicase_C PF00271.26 KLO14115.1 - 1.5e-07 31.1 0.0 1.1e-06 28.4 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ERG2_Sigma1R PF04622.7 KLO14116.1 - 7.4e-84 280.3 0.2 9.1e-84 280.0 0.2 1.0 1 0 0 1 1 1 1 ERG2 and Sigma1 receptor like protein F-box-like PF12937.2 KLO14118.1 - 0.00055 19.6 3.2 0.00061 19.4 0.3 2.6 2 0 0 2 2 2 1 F-box-like Pkinase PF00069.20 KLO14121.1 - 1.1e-44 152.5 0.0 1.4e-44 152.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KLO14121.1 - 1.5e-38 132.3 0.0 1.9e-38 132.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KLO14121.1 - 4e-06 26.0 0.0 3.8e-05 22.7 0.0 1.9 2 0 0 2 2 2 1 Kinase-like RIO1 PF01163.17 KLO14121.1 - 0.00043 19.6 0.6 0.0096 15.2 0.0 2.1 1 1 0 2 2 2 1 RIO1 family APH PF01636.18 KLO14121.1 - 0.055 13.1 0.0 0.082 12.6 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.9 KLO14121.1 - 0.058 12.4 0.0 0.086 11.8 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family STE3 PF02076.10 KLO14122.1 - 6.2e-63 212.5 18.8 7.2e-63 212.3 13.0 1.0 1 0 0 1 1 1 1 Pheromone A receptor F-box-like PF12937.2 KLO14123.1 - 1.9e-06 27.4 1.0 5.9e-06 25.9 0.7 1.9 1 0 0 1 1 1 1 F-box-like PCDO_beta_N PF12391.3 KLO14123.1 - 0.32 10.4 2.5 0.86 9.0 1.7 1.8 1 0 0 1 1 1 0 Protocatechuate 3,4-dioxygenase beta subunit N terminal DUF2235 PF09994.4 KLO14124.1 - 2.3e-63 214.1 0.5 3.4e-63 213.6 0.3 1.2 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) RNA_pol_I_TF PF04090.7 KLO14124.1 - 0.034 13.4 0.0 0.21 10.8 0.0 2.1 2 0 0 2 2 2 0 RNA polymerase I specific initiation factor Abhydrolase_5 PF12695.2 KLO14124.1 - 0.11 12.2 0.0 0.17 11.6 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family F-box-like PF12937.2 KLO14125.1 - 3.6e-05 23.3 2.1 7.1e-05 22.4 0.6 2.2 2 0 0 2 2 2 1 F-box-like F-box-like PF12937.2 KLO14126.1 - 1e-05 25.1 0.3 3.1e-05 23.6 0.2 1.8 1 0 0 1 1 1 1 F-box-like STE3 PF02076.10 KLO14127.1 - 1.2e-57 195.1 14.9 1.4e-57 194.9 10.3 1.1 1 0 0 1 1 1 1 Pheromone A receptor TcpE PF12648.2 KLO14127.1 - 1.1 9.4 9.4 0.19 11.9 1.6 3.0 3 0 0 3 3 3 0 TcpE family STE3 PF02076.10 KLO14128.1 - 2.9e-66 223.4 17.3 3.3e-66 223.2 12.0 1.0 1 0 0 1 1 1 1 Pheromone A receptor SPC25 PF06703.6 KLO14129.1 - 1.2e-42 145.2 0.1 1.4e-42 145.0 0.1 1.0 1 0 0 1 1 1 1 Microsomal signal peptidase 25 kDa subunit (SPC25) DUF2207 PF09972.4 KLO14129.1 - 0.053 12.1 0.0 0.053 12.1 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF4231 PF14015.1 KLO14129.1 - 0.06 13.3 0.2 0.085 12.8 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4231) DUF3093 PF11292.3 KLO14129.1 - 0.063 13.0 0.1 0.092 12.5 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3093) ERG2_Sigma1R PF04622.7 KLO14130.1 - 1.6e-90 302.0 0.5 1.8e-90 301.9 0.4 1.0 1 0 0 1 1 1 1 ERG2 and Sigma1 receptor like protein F-box-like PF12937.2 KLO14132.1 - 1.6e-07 30.9 0.3 2.7e-06 27.0 0.1 2.4 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 KLO14132.1 - 0.74 9.5 6.7 5.1 6.8 0.2 3.6 4 0 0 4 4 4 0 F-box domain STE3 PF02076.10 KLO14134.1 - 5.4e-50 170.0 26.2 5e-49 166.9 18.2 1.9 1 1 0 1 1 1 1 Pheromone A receptor STE3 PF02076.10 KLO14136.1 - 1.5e-56 191.5 9.4 1.8e-56 191.3 6.5 1.0 1 0 0 1 1 1 1 Pheromone A receptor CreD PF06123.7 KLO14137.1 - 3.1 6.2 4.8 4.5 5.7 3.3 1.1 1 0 0 1 1 1 0 Inner membrane protein CreD DUF605 PF04652.11 KLO14137.1 - 6 6.1 18.9 8 5.7 13.1 1.2 1 0 0 1 1 1 0 Vta1 like Pkinase PF00069.20 KLO14139.1 - 2.3e-49 167.9 0.0 3.2e-49 167.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KLO14139.1 - 1e-44 152.5 0.0 1.5e-44 152.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KLO14139.1 - 3.6e-05 22.8 0.0 5.4e-05 22.2 0.0 1.2 1 0 0 1 1 1 1 Kinase-like zf-FPG_IleRS PF06827.9 KLO14139.1 - 9.5 5.9 12.3 5 6.8 1.8 2.5 2 0 0 2 2 2 0 Zinc finger found in FPG and IleRS KCl_Cotrans_1 PF03522.10 KLO14140.1 - 1.6 8.3 7.3 16 5.0 2.8 3.1 2 0 0 2 2 2 0 K-Cl Co-transporter type 1 (KCC1) Pkinase PF00069.20 KLO14143.1 - 1.7e-44 151.9 0.0 2.7e-44 151.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KLO14143.1 - 3e-40 137.9 0.0 4.3e-40 137.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KLO14143.1 - 0.00015 20.8 0.0 0.00083 18.3 0.0 1.9 1 1 0 1 1 1 1 Kinase-like APH PF01636.18 KLO14143.1 - 0.0056 16.4 1.9 0.0058 16.3 0.0 1.9 3 0 0 3 3 3 1 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.6 KLO14143.1 - 0.25 10.1 0.0 0.37 9.5 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase GATA PF00320.22 KLO14145.1 - 4.6e-16 57.8 5.0 7e-16 57.2 3.5 1.3 1 0 0 1 1 1 1 GATA zinc finger eIF-5_eIF-2B PF01873.12 KLO14145.1 - 0.17 11.5 0.3 0.23 11.1 0.2 1.2 1 0 0 1 1 1 0 Domain found in IF2B/IF5 Ribosomal_L32p PF01783.18 KLO14145.1 - 0.56 10.4 4.4 7.7 6.7 3.1 2.4 1 1 0 1 1 1 0 Ribosomal L32p protein family HycH PF07450.6 KLO14146.1 - 0.031 14.3 0.0 0.056 13.5 0.0 1.3 1 0 0 1 1 1 0 Formate hydrogenlyase maturation protein HycH Zn_clus PF00172.13 KLO14147.1 - 6.4e-06 25.9 3.6 8.8e-06 25.5 2.5 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pox_M2 PF04887.7 KLO14147.1 - 0.13 11.5 0.1 0.13 11.5 0.0 1.2 1 0 0 1 1 1 0 Poxvirus M2 protein FAD_binding_3 PF01494.14 KLO14148.1 - 6.2e-17 61.6 0.1 1.7e-10 40.4 0.0 3.0 2 1 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.1 KLO14148.1 - 0.0012 18.8 0.1 0.0029 17.5 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 KLO14148.1 - 0.016 14.0 0.0 0.036 12.9 0.0 1.6 1 0 0 1 1 1 0 FAD binding domain Pyr_redox_2 PF07992.9 KLO14148.1 - 0.049 13.4 0.0 0.09 12.6 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase zf-MYND PF01753.13 KLO14149.1 - 9.2e-10 38.2 12.1 2.2e-09 37.0 8.4 1.7 1 0 0 1 1 1 1 MYND finger zf-MYND PF01753.13 KLO14150.1 - 1.4e-09 37.6 11.6 3e-09 36.6 8.0 1.6 1 0 0 1 1 1 1 MYND finger Pkinase PF00069.20 KLO14151.1 - 8.4e-44 149.6 0.0 9.8e-44 149.4 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KLO14151.1 - 3.3e-39 134.5 0.0 3.7e-39 134.3 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KLO14151.1 - 1.5e-06 27.3 0.0 2.1e-06 26.9 0.0 1.1 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 KLO14151.1 - 0.012 14.6 0.0 0.02 13.9 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Transferase PF02458.10 KLO14152.1 - 6.8e-32 110.4 0.0 1.7e-31 109.1 0.0 1.4 1 1 0 1 1 1 1 Transferase family Abhydrolase_6 PF12697.2 KLO14153.1 - 7.6e-23 81.5 0.0 9.4e-23 81.2 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 KLO14153.1 - 1.7e-18 66.2 0.0 9e-18 63.9 0.0 1.9 2 0 0 2 2 2 1 Putative lysophospholipase Abhydrolase_5 PF12695.2 KLO14153.1 - 7.7e-18 64.6 0.0 1.2e-17 64.0 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 KLO14153.1 - 2.8e-07 29.9 0.0 0.00034 19.8 0.0 2.1 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_1 PF00561.15 KLO14153.1 - 0.00036 20.1 0.1 0.00082 19.0 0.0 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_2 PF02230.11 KLO14153.1 - 0.00082 18.8 0.3 0.61 9.4 0.0 2.8 2 1 1 3 3 3 2 Phospholipase/Carboxylesterase Abhydrolase_3 PF07859.8 KLO14153.1 - 0.0041 16.7 0.0 0.0093 15.5 0.0 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold AXE1 PF05448.7 KLO14153.1 - 0.0051 15.3 0.0 0.86 8.0 0.0 2.8 3 0 0 3 3 3 1 Acetyl xylan esterase (AXE1) DLH PF01738.13 KLO14153.1 - 0.011 15.0 0.0 0.93 8.7 0.0 2.2 2 0 0 2 2 2 0 Dienelactone hydrolase family Esterase PF00756.15 KLO14153.1 - 0.011 15.1 0.0 0.025 13.9 0.0 1.6 1 1 0 1 1 1 0 Putative esterase Macro PF01661.16 KLO14154.1 - 2.9e-42 143.2 0.3 4.3e-42 142.7 0.2 1.2 1 0 0 1 1 1 1 Macro domain DUF1680 PF07944.7 KLO14155.1 - 1e-124 416.6 0.0 1.2e-124 416.4 0.0 1.0 1 0 0 1 1 1 1 Putative glycosyl hydrolase of unknown function (DUF1680) Glyco_hydro_47 PF01532.15 KLO14156.1 - 1.3e-128 429.5 0.0 1.5e-128 429.2 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Pkinase_Tyr PF07714.12 KLO14157.1 - 7.3e-41 139.9 0.0 1e-40 139.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 KLO14157.1 - 1.2e-40 139.3 0.0 1.7e-40 138.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.1 KLO14157.1 - 0.0023 16.9 0.0 0.0037 16.2 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Phage_NinH PF06322.6 KLO14157.1 - 0.088 12.4 0.0 0.23 11.1 0.0 1.6 1 0 0 1 1 1 0 Phage NinH protein DUF1896 PF08989.5 KLO14159.1 - 0.018 14.9 0.0 0.044 13.6 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1896) EF-hand_1 PF00036.27 KLO14161.1 - 3.2e-24 82.3 1.1 1.5e-05 23.9 0.1 5.1 4 1 0 4 4 4 4 EF hand EF-hand_6 PF13405.1 KLO14161.1 - 4e-21 72.9 0.5 2.2e-05 23.9 0.1 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_7 PF13499.1 KLO14161.1 - 3.6e-20 71.8 0.0 3.6e-09 36.6 0.0 2.3 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.1 KLO14161.1 - 1.8e-17 61.7 1.7 0.0013 17.9 0.0 4.6 4 1 0 4 4 4 4 EF hand EF-hand_8 PF13833.1 KLO14161.1 - 3.6e-15 55.2 4.2 3.3e-09 36.2 0.0 4.0 3 2 1 4 4 4 4 EF-hand domain pair GUN4 PF05419.7 KLO14161.1 - 0.021 14.6 0.0 1.7 8.4 0.0 2.4 2 0 0 2 2 2 0 GUN4-like EF-hand_4 PF12763.2 KLO14161.1 - 0.11 12.2 2.2 0.13 12.0 0.2 1.9 2 0 0 2 2 2 0 Cytoskeletal-regulatory complex EF hand AMP-binding PF00501.23 KLO14162.1 - 3.7e-86 289.1 0.0 4.9e-86 288.7 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 KLO14162.1 - 0.049 14.5 0.2 0.16 12.9 0.1 1.9 1 1 0 1 1 1 0 AMP-binding enzyme C-terminal domain MFS_1 PF07690.11 KLO14164.1 - 5.3e-29 101.0 28.3 8.6e-29 100.3 19.6 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_1_like PF12832.2 KLO14164.1 - 0.0024 17.6 1.0 0.026 14.3 0.1 2.8 2 0 0 2 2 2 1 MFS_1 like family Peptidase_M24 PF00557.19 KLO14165.1 - 9e-38 129.9 0.1 1.4e-37 129.3 0.0 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 Creatinase_N PF01321.13 KLO14165.1 - 2.2e-06 28.1 0.0 5.2e-06 26.9 0.0 1.7 1 1 0 1 1 1 1 Creatinase/Prolidase N-terminal domain BSD PF03909.12 KLO14166.1 - 0.014 15.1 1.0 0.021 14.5 0.7 1.3 1 0 0 1 1 1 0 BSD domain GET2 PF08690.5 KLO14166.1 - 0.4 9.8 2.2 0.4 9.8 1.5 1.0 1 0 0 1 1 1 0 GET complex subunit GET2 IATP PF04568.7 KLO14166.1 - 1.8 8.6 8.8 0.28 11.2 3.0 1.7 1 1 1 2 2 2 0 Mitochondrial ATPase inhibitor, IATP Cellulase PF00150.13 KLO14167.1 - 5.4e-10 38.9 0.0 9.2e-10 38.1 0.0 1.4 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) DUF3357 PF11837.3 KLO14167.1 - 0.018 14.9 0.0 0.032 14.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3357) DUF4064 PF13273.1 KLO14167.1 - 0.02 15.0 0.0 0.038 14.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4064) Omp28 PF11551.3 KLO14168.1 - 0.074 12.5 0.0 0.1 12.1 0.0 1.1 1 0 0 1 1 1 0 Outer membrane protein Omp28 CBFD_NFYB_HMF PF00808.18 KLO14169.1 - 3.4e-06 27.0 0.0 4.8e-06 26.5 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Cellulase PF00150.13 KLO14171.1 - 7.9e-11 41.6 0.0 7.9e-11 41.6 0.0 1.5 2 0 0 2 2 2 1 Cellulase (glycosyl hydrolase family 5) VirB8 PF04335.8 KLO14171.1 - 0.16 11.5 0.1 0.28 10.7 0.1 1.3 1 0 0 1 1 1 0 VirB8 protein DUF515 PF04415.7 KLO14171.1 - 0.3 9.2 0.1 0.49 8.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF515) Pectate_lyase_3 PF12708.2 KLO14172.1 - 1e-76 257.9 25.1 1.4e-59 201.9 4.3 3.2 3 0 0 3 3 3 2 Pectate lyase superfamily protein End_N_terminal PF12218.3 KLO14172.1 - 6.8e-09 35.0 2.3 0.0016 17.8 0.0 2.8 2 0 0 2 2 2 2 N terminal extension of bacteriophage endosialidase Acetyltransf_13 PF13880.1 KLO14173.1 - 5.3e-15 54.9 0.0 9.9e-15 54.0 0.0 1.5 1 0 0 1 1 1 1 ESCO1/2 acetyl-transferase zf-C2H2_3 PF13878.1 KLO14173.1 - 6.1e-07 28.9 0.2 1.1e-06 28.1 0.1 1.4 1 0 0 1 1 1 1 zinc-finger of acetyl-transferase ESCO Acetyltransf_1 PF00583.19 KLO14173.1 - 3.4e-06 26.9 0.0 7.6e-06 25.8 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 KLO14173.1 - 0.002 18.2 0.0 0.0057 16.7 0.0 1.9 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 KLO14173.1 - 0.038 14.1 0.0 0.088 12.9 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Scramblase PF03803.10 KLO14175.1 - 3.4e-44 150.5 0.0 5e-43 146.7 0.0 1.9 1 1 0 1 1 1 1 Scramblase GTP_EFTU PF00009.22 KLO14176.1 - 1.7e-39 135.1 0.1 8.5e-39 132.9 0.1 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain IF-2 PF11987.3 KLO14176.1 - 5.9e-27 93.7 2.2 1.4e-26 92.5 1.5 1.6 1 0 0 1 1 1 1 Translation-initiation factor 2 MMR_HSR1 PF01926.18 KLO14176.1 - 5.3e-07 29.6 0.1 1.8e-06 27.8 0.0 2.0 2 0 0 2 2 2 1 50S ribosome-binding GTPase PduV-EutP PF10662.4 KLO14176.1 - 6.3e-05 22.4 0.3 0.069 12.6 0.0 2.6 2 0 0 2 2 2 2 Ethanolamine utilisation - propanediol utilisation Miro PF08477.8 KLO14176.1 - 0.00084 19.8 0.1 0.0019 18.6 0.0 1.7 1 0 0 1 1 1 1 Miro-like protein ArgK PF03308.11 KLO14176.1 - 0.0015 17.3 0.6 0.0015 17.3 0.4 2.5 3 0 0 3 3 3 1 ArgK protein SRPRB PF09439.5 KLO14176.1 - 0.0029 16.8 0.1 0.0073 15.5 0.0 1.7 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit MobB PF03205.9 KLO14176.1 - 0.019 14.6 0.1 0.069 12.8 0.0 2.1 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B Dynamin_N PF00350.18 KLO14176.1 - 0.061 13.1 1.0 3.8 7.2 0.1 2.6 1 1 1 2 2 2 0 Dynamin family GTP_EFTU_D2 PF03144.20 KLO14176.1 - 0.13 12.4 6.8 0.36 10.9 0.0 4.0 5 0 0 5 5 5 0 Elongation factor Tu domain 2 CHORD PF04968.7 KLO14177.1 - 2e-47 159.2 13.5 1.6e-24 85.9 1.6 2.4 2 0 0 2 2 2 2 CHORD CS PF04969.11 KLO14177.1 - 1e-14 54.8 0.0 2e-14 53.8 0.0 1.5 1 0 0 1 1 1 1 CS domain BTK PF00779.14 KLO14177.1 - 0.15 11.6 4.7 5.7 6.6 0.1 2.9 2 0 0 2 2 2 0 BTK motif Mito_carr PF00153.22 KLO14178.1 - 1.3e-10 40.8 0.1 0.00018 21.1 0.0 3.8 2 1 1 3 3 3 3 Mitochondrial carrier protein 2OG-FeII_Oxy_2 PF13532.1 KLO14179.1 - 8.1e-13 48.6 0.0 1.2e-12 48.1 0.0 1.2 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily WD40 PF00400.27 KLO14181.1 - 2.1e-48 160.5 13.6 5.2e-13 48.3 0.0 8.0 8 0 0 8 8 8 7 WD domain, G-beta repeat Nup160 PF11715.3 KLO14181.1 - 1.1e-05 23.7 2.5 0.49 8.4 0.0 4.3 3 1 1 5 5 5 3 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 KLO14181.1 - 2.8e-05 23.0 2.7 0.012 14.4 0.0 4.3 1 1 2 4 4 4 1 Nup133 N terminal like Hira PF07569.6 KLO14181.1 - 0.0072 15.5 0.0 1.1 8.4 0.0 2.7 2 0 0 2 2 2 2 TUP1-like enhancer of split Gmad1 PF10647.4 KLO14181.1 - 0.029 13.7 0.0 0.062 12.6 0.0 1.5 1 1 0 1 1 1 0 Lipoprotein LpqB beta-propeller domain DUF866 PF05907.8 KLO14181.1 - 0.074 12.5 0.0 0.12 11.8 0.0 1.3 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF866) PAN_3 PF08277.7 KLO14181.1 - 0.075 12.6 0.1 0.22 11.1 0.0 1.8 1 0 0 1 1 1 0 PAN-like domain Glu_synthase PF01645.12 KLO14182.1 - 3.8e-160 532.7 0.1 4e-159 529.4 0.0 2.1 2 0 0 2 2 2 1 Conserved region in glutamate synthase GATase_2 PF00310.16 KLO14182.1 - 6.3e-136 452.8 0.0 8.5e-136 452.3 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferases class-II Glu_syn_central PF04898.9 KLO14182.1 - 1.5e-120 401.8 0.0 2.3e-120 401.2 0.0 1.3 1 0 0 1 1 1 1 Glutamate synthase central domain GXGXG PF01493.14 KLO14182.1 - 3.6e-69 231.8 3.8 3.6e-69 231.8 2.6 1.8 2 0 0 2 2 2 1 GXGXG motif Fer4_20 PF14691.1 KLO14182.1 - 7.5e-22 77.0 0.0 1.8e-21 75.8 0.0 1.6 1 0 0 1 1 1 1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster Pyr_redox_2 PF07992.9 KLO14182.1 - 8.8e-17 61.6 0.0 2.1e-16 60.4 0.0 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 KLO14182.1 - 5.2e-10 39.7 0.3 3.6e-05 23.9 0.0 2.5 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KLO14182.1 - 3.4e-09 36.5 0.0 1.4e-08 34.6 0.0 2.1 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 KLO14182.1 - 1.5e-07 31.6 0.5 0.00033 21.0 0.0 3.9 4 0 0 4 4 3 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 KLO14182.1 - 9.8e-07 27.9 0.1 8.5e-05 21.6 0.0 2.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.9 KLO14182.1 - 1.7e-05 23.5 0.1 1.7e-05 23.5 0.1 2.0 3 0 0 3 3 3 1 HI0933-like protein Amino_oxidase PF01593.19 KLO14182.1 - 0.0001 21.5 0.0 0.00016 20.9 0.0 1.3 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase FAD_binding_2 PF00890.19 KLO14182.1 - 0.00012 21.0 0.0 0.001 18.0 0.0 2.4 2 0 0 2 2 2 1 FAD binding domain NAD_Gly3P_dh_N PF01210.18 KLO14182.1 - 0.003 17.2 0.2 0.012 15.4 0.0 2.0 2 0 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus FMN_dh PF01070.13 KLO14182.1 - 0.0039 16.0 0.4 0.015 14.1 0.4 1.8 2 0 0 2 2 2 1 FMN-dependent dehydrogenase FAD_oxidored PF12831.2 KLO14182.1 - 0.0041 16.2 0.0 0.008 15.2 0.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.12 KLO14182.1 - 0.0047 16.0 1.4 0.0062 15.6 0.0 1.9 2 0 0 2 2 2 1 Thi4 family FAD_binding_3 PF01494.14 KLO14182.1 - 0.0052 15.8 0.0 0.011 14.8 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain NAD_binding_7 PF13241.1 KLO14182.1 - 0.015 15.5 0.9 1.1 9.5 0.1 2.7 2 0 0 2 2 2 0 Putative NAD(P)-binding UDPG_MGDP_dh_N PF03721.9 KLO14182.1 - 0.017 14.4 0.0 0.06 12.7 0.0 1.9 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NAD_binding_2 PF03446.10 KLO14182.1 - 0.018 14.9 0.1 0.051 13.4 0.0 1.8 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase 3HCDH_N PF02737.13 KLO14182.1 - 0.029 14.0 0.2 0.072 12.7 0.1 1.7 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_9 PF13454.1 KLO14182.1 - 0.037 13.8 0.1 0.12 12.1 0.0 1.9 2 0 0 2 2 1 0 FAD-NAD(P)-binding ApbA PF02558.11 KLO14182.1 - 0.039 13.3 0.0 0.082 12.3 0.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA NAD_binding_10 PF13460.1 KLO14182.1 - 0.052 13.5 0.1 0.46 10.4 0.1 2.5 1 1 0 1 1 1 0 NADH(P)-binding GATase_6 PF13522.1 KLO14182.1 - 0.058 13.3 0.1 0.15 11.9 0.1 1.6 1 0 0 1 1 1 0 Glutamine amidotransferase domain Lycopene_cycl PF05834.7 KLO14182.1 - 0.17 10.7 1.6 0.82 8.5 0.0 2.5 3 0 0 3 3 3 0 Lycopene cyclase protein GIDA PF01134.17 KLO14182.1 - 0.23 10.2 1.2 0.71 8.6 0.0 2.1 2 0 0 2 2 2 0 Glucose inhibited division protein A dCMP_cyt_deam_1 PF00383.17 KLO14183.1 - 7.4e-15 54.4 0.1 1.2e-14 53.7 0.1 1.4 1 1 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region APOBEC_N PF08210.6 KLO14183.1 - 0.0059 16.2 0.0 0.04 13.5 0.0 1.9 1 1 0 1 1 1 1 APOBEC-like N-terminal domain XOO_2897-deam PF14440.1 KLO14183.1 - 0.14 11.8 0.2 0.57 9.8 0.1 2.1 2 1 0 2 2 2 0 Xanthomonas XOO_2897-like deaminase Condensation PF00668.15 KLO14184.1 - 2.5e-106 354.9 0.3 1.5e-35 122.4 0.0 3.4 3 0 0 3 3 3 3 Condensation domain AMP-binding PF00501.23 KLO14184.1 - 1e-88 297.5 0.0 1.6e-88 296.9 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme PP-binding PF00550.20 KLO14184.1 - 5.3e-25 87.4 10.3 1e-10 41.7 0.2 4.2 4 0 0 4 4 4 3 Phosphopantetheine attachment site AMP-binding_C PF13193.1 KLO14184.1 - 0.0042 17.9 0.0 0.013 16.4 0.0 1.9 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain K_oxygenase PF13434.1 KLO14186.1 - 3.8e-90 302.2 0.0 5.6e-90 301.6 0.0 1.3 1 0 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.1 KLO14186.1 - 2.7e-09 36.9 0.0 2e-07 30.9 0.0 2.7 3 0 0 3 3 3 1 FAD-NAD(P)-binding Pyr_redox_3 PF13738.1 KLO14186.1 - 6.7e-05 23.0 0.0 0.00013 22.0 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 KLO14186.1 - 0.037 12.9 0.0 0.059 12.2 0.0 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase Ribosomal_L24e PF01246.15 KLO14187.1 - 3.1e-32 110.2 4.0 5.9e-32 109.3 2.8 1.4 1 0 0 1 1 1 1 Ribosomal protein L24e zf-FCS PF06467.9 KLO14187.1 - 0.0011 18.5 4.5 0.0022 17.5 3.1 1.5 1 0 0 1 1 1 1 MYM-type Zinc finger with FCS sequence motif Bac_luciferase PF00296.15 KLO14187.1 - 0.12 11.4 0.0 0.13 11.3 0.0 1.1 1 0 0 1 1 1 0 Luciferase-like monooxygenase DUF2116 PF09889.4 KLO14187.1 - 0.47 10.2 3.2 0.28 10.9 0.5 1.9 2 0 0 2 2 2 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) ATG_C PF09333.6 KLO14188.1 - 6.1e-28 96.8 0.2 1.9e-27 95.2 0.1 2.0 2 0 0 2 2 2 1 ATG C terminal domain Chorein_N PF12624.2 KLO14188.1 - 9.6e-10 38.0 0.0 2.2e-09 36.8 0.0 1.6 1 0 0 1 1 1 1 N-terminal region of Chorein, a TM vesicle-mediated sorter ATG2_CAD PF13329.1 KLO14188.1 - 7.1e-08 32.1 0.1 2.2e-07 30.5 0.0 1.9 1 0 0 1 1 1 1 Autophagy-related protein 2 CAD motif Choline_transpo PF04515.7 KLO14189.1 - 2e-20 72.8 10.6 2e-20 72.8 7.3 2.6 2 2 0 2 2 2 1 Plasma-membrane choline transporter DUF2360 PF10152.4 KLO14189.1 - 6.5 7.0 7.4 25 5.1 0.5 2.5 2 0 0 2 2 2 0 Predicted coiled-coil domain-containing protein (DUF2360) Ribosomal_L37 PF08561.5 KLO14190.1 - 1.6e-21 75.6 2.1 3.4e-21 74.5 1.5 1.5 1 1 0 1 1 1 1 Mitochondrial ribosomal protein L37 WD40 PF00400.27 KLO14191.1 - 2.4e-06 27.2 13.6 1.4 8.8 0.1 5.8 5 0 0 5 5 5 4 WD domain, G-beta repeat Apc4_WD40 PF12894.2 KLO14191.1 - 0.0056 16.1 1.5 1.5 8.4 0.0 3.3 3 0 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain DUF2890 PF11081.3 KLO14191.1 - 1.9 8.4 7.3 4.4 7.3 5.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) Nop14 PF04147.7 KLO14191.1 - 2.2 6.0 11.3 3.7 5.3 7.8 1.2 1 0 0 1 1 1 0 Nop14-like family Lin-8 PF03353.10 KLO14191.1 - 5.8 6.0 5.7 8.7 5.5 3.9 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist ADH_zinc_N PF00107.21 KLO14192.1 - 5.5e-28 97.1 0.2 8.9e-28 96.4 0.2 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 KLO14192.1 - 8.1e-14 52.6 0.1 2.2e-13 51.1 0.0 1.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KLO14192.1 - 2.1e-07 30.6 0.0 1.2e-06 28.2 0.0 2.3 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ACP_syn_III_C PF08541.5 KLO14192.1 - 7.2e-05 22.7 0.1 0.015 15.2 0.1 2.5 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal ELFV_dehydrog PF00208.16 KLO14192.1 - 0.043 13.3 0.5 0.071 12.6 0.4 1.3 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase HP_OMP_2 PF02521.9 KLO14192.1 - 0.098 11.2 0.0 0.14 10.7 0.0 1.1 1 0 0 1 1 1 0 Putative outer membrane protein zf-C3HC4_3 PF13920.1 KLO14194.1 - 2.7e-05 23.7 8.1 2.7e-05 23.7 5.6 3.0 3 0 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) DUF2316 PF10078.4 KLO14195.1 - 0.61 10.1 3.3 6.9 6.7 0.0 2.8 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2316) Fib_alpha PF08702.5 KLO14195.1 - 0.81 9.8 13.5 4.8 7.2 0.1 4.3 4 0 0 4 4 4 0 Fibrinogen alpha/beta chain family UCH PF00443.24 KLO14197.1 - 1.1e-46 159.1 0.0 1.8e-46 158.4 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase COX4 PF02936.9 KLO14197.1 - 4.3e-37 126.9 0.0 7.2e-37 126.2 0.0 1.3 1 0 0 1 1 1 1 Cytochrome c oxidase subunit IV UCH_1 PF13423.1 KLO14197.1 - 5.5e-17 62.1 0.0 3e-12 46.5 0.0 2.2 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase ATP-synt_Eps PF04627.8 KLO14198.1 - 2.9e-22 77.9 3.0 3.6e-22 77.6 2.1 1.1 1 0 0 1 1 1 1 Mitochondrial ATP synthase epsilon chain Ras PF00071.17 KLO14199.1 - 8.6e-51 171.5 0.0 1e-50 171.3 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KLO14199.1 - 2e-15 57.3 0.0 2.8e-15 56.8 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KLO14199.1 - 2.5e-12 46.3 0.0 2.9e-12 46.1 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 KLO14199.1 - 7.2e-06 25.5 0.0 0.00038 19.9 0.0 2.1 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 KLO14199.1 - 0.00099 19.0 0.0 0.0026 17.7 0.0 1.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase DSPc PF00782.15 KLO14200.1 - 1.6e-29 102.1 0.0 1.8e-29 102.0 0.0 1.0 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 KLO14200.1 - 0.0048 16.2 0.0 0.0055 16.0 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Init_tRNA_PT PF04179.7 KLO14200.1 - 0.036 12.9 0.0 0.036 12.9 0.0 1.0 1 0 0 1 1 1 0 Initiator tRNA phosphoribosyl transferase Phage_CI_repr PF07022.8 KLO14200.1 - 0.045 13.8 0.0 0.35 10.9 0.0 2.1 2 0 0 2 2 2 0 Bacteriophage CI repressor helix-turn-helix domain DUF4184 PF13803.1 KLO14200.1 - 0.058 12.7 0.2 0.092 12.0 0.1 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4184) Myotub-related PF06602.9 KLO14200.1 - 0.15 10.8 0.1 0.22 10.2 0.1 1.2 1 0 0 1 1 1 0 Myotubularin-like phosphatase domain DEAD PF00270.24 KLO14201.1 - 4.5e-43 146.6 3.0 4.6e-43 146.6 0.6 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KLO14201.1 - 7e-27 93.1 0.2 3e-26 91.0 0.1 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 KLO14201.1 - 0.00018 21.3 0.0 0.00034 20.4 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_19 PF13245.1 KLO14201.1 - 0.0002 21.0 0.1 0.00049 19.7 0.0 1.7 1 0 0 1 1 1 1 Part of AAA domain Flavi_DEAD PF07652.9 KLO14201.1 - 0.0062 16.3 0.2 0.024 14.3 0.1 2.1 1 1 0 1 1 1 1 Flavivirus DEAD domain AAA_11 PF13086.1 KLO14201.1 - 0.0084 15.7 0.8 0.013 15.1 0.6 1.5 1 1 0 1 1 1 1 AAA domain UvrD-helicase PF00580.16 KLO14201.1 - 0.0088 15.3 0.1 0.011 15.1 0.1 1.3 1 0 0 1 1 1 1 UvrD/REP helicase N-terminal domain AAA_30 PF13604.1 KLO14201.1 - 0.011 15.2 0.1 0.053 13.0 0.1 2.0 2 0 0 2 2 2 0 AAA domain Helicase_RecD PF05127.9 KLO14201.1 - 0.03 13.9 0.0 0.055 13.1 0.0 1.4 1 0 0 1 1 1 0 Helicase CMS1 PF14617.1 KLO14201.1 - 0.067 12.2 0.1 0.28 10.2 0.0 1.9 2 0 0 2 2 2 0 U3-containing 90S pre-ribosomal complex subunit Zn_Tnp_IS1595 PF12760.2 KLO14202.1 - 0.0012 18.5 3.8 0.0046 16.7 2.6 1.8 1 1 0 1 1 1 1 Transposase zinc-ribbon domain zf-Sec23_Sec24 PF04810.10 KLO14202.1 - 0.093 12.3 0.7 0.093 12.3 0.5 2.5 3 0 0 3 3 3 0 Sec23/Sec24 zinc finger Rubredoxin PF00301.15 KLO14202.1 - 0.13 12.2 0.1 0.13 12.2 0.1 3.2 3 0 0 3 3 3 0 Rubredoxin zf-BED PF02892.10 KLO14202.1 - 1.4 8.7 4.5 2.8 7.7 0.6 2.1 1 1 1 2 2 2 0 BED zinc finger Asp PF00026.18 KLO14203.1 - 1e-39 136.6 0.0 1.5e-39 136.1 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 KLO14203.1 - 0.00097 19.1 0.1 0.0018 18.2 0.1 1.5 1 0 0 1 1 1 1 Xylanase inhibitor N-terminal Ras PF00071.17 KLO14204.1 - 1.3e-63 213.1 0.5 1.6e-63 212.9 0.3 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KLO14204.1 - 2.4e-20 73.2 0.0 3.9e-20 72.5 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KLO14204.1 - 1.6e-16 60.0 0.1 2.1e-16 59.6 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 KLO14204.1 - 6.5e-06 25.4 0.0 9.1e-06 24.9 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 KLO14204.1 - 1.2e-05 24.8 0.1 2.5e-05 23.7 0.1 1.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain SRPRB PF09439.5 KLO14204.1 - 4.2e-05 22.8 0.1 7.2e-05 22.0 0.1 1.5 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.18 KLO14204.1 - 0.00015 21.7 0.1 0.00029 20.7 0.1 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA PF00004.24 KLO14204.1 - 0.0017 18.5 0.1 0.33 11.1 0.0 2.2 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 KLO14204.1 - 0.0029 17.7 0.0 0.0053 16.9 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 KLO14204.1 - 0.0077 16.2 0.3 0.033 14.1 0.2 2.2 1 1 0 1 1 1 1 AAA ATPase domain DUF258 PF03193.11 KLO14204.1 - 0.0094 15.1 0.1 0.021 13.9 0.0 1.7 1 1 0 1 1 1 1 Protein of unknown function, DUF258 AAA_5 PF07728.9 KLO14204.1 - 0.021 14.5 0.0 0.046 13.4 0.0 1.6 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_29 PF13555.1 KLO14204.1 - 0.025 14.1 0.0 0.11 12.0 0.0 2.0 2 0 0 2 2 2 0 P-loop containing region of AAA domain FeoB_N PF02421.13 KLO14204.1 - 0.025 13.8 0.0 0.15 11.3 0.0 1.9 1 1 0 1 1 1 0 Ferrous iron transport protein B ABC_tran PF00005.22 KLO14204.1 - 0.064 13.5 0.2 0.24 11.6 0.1 1.9 1 1 0 1 1 1 0 ABC transporter Septin PF00735.13 KLO14204.1 - 0.1 11.5 0.0 0.21 10.5 0.0 1.4 1 0 0 1 1 1 0 Septin Piwi PF02171.12 KLO14205.1 - 1.2e-70 237.8 0.0 1.8e-70 237.3 0.0 1.3 1 0 0 1 1 1 1 Piwi domain DUF1785 PF08699.5 KLO14205.1 - 9e-12 44.1 0.2 2.2e-11 42.9 0.1 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1785) PAZ PF02170.17 KLO14205.1 - 9e-06 25.0 0.0 1.7e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 PAZ domain SOR_SNZ PF01680.12 KLO14206.1 - 1e-112 374.8 5.8 1.5e-112 374.2 4.0 1.2 1 0 0 1 1 1 1 SOR/SNZ family ThiG PF05690.9 KLO14206.1 - 2.4e-10 39.9 3.1 1.6e-07 30.6 0.1 2.3 2 0 0 2 2 2 2 Thiazole biosynthesis protein ThiG Dus PF01207.12 KLO14206.1 - 9.5e-06 24.6 0.4 0.019 13.7 0.0 2.4 2 1 0 2 2 2 2 Dihydrouridine synthase (Dus) NMO PF03060.10 KLO14206.1 - 0.00016 20.9 5.9 0.0023 17.1 0.2 2.4 2 0 0 2 2 2 2 Nitronate monooxygenase IGPS PF00218.16 KLO14206.1 - 0.00018 20.6 0.1 0.00082 18.4 0.0 1.9 2 0 0 2 2 2 1 Indole-3-glycerol phosphate synthase His_biosynth PF00977.16 KLO14206.1 - 0.00082 18.7 0.2 0.11 11.7 0.0 3.0 3 0 0 3 3 3 1 Histidine biosynthesis protein NanE PF04131.9 KLO14206.1 - 0.0013 17.7 0.2 0.081 11.8 0.0 2.4 2 0 0 2 2 2 1 Putative N-acetylmannosamine-6-phosphate epimerase FMN_dh PF01070.13 KLO14206.1 - 0.016 14.0 0.0 0.029 13.2 0.0 1.4 1 0 0 1 1 1 0 FMN-dependent dehydrogenase Trp_syntA PF00290.15 KLO14206.1 - 0.032 12.7 0.0 0.061 11.8 0.0 1.4 1 0 0 1 1 1 0 Tryptophan synthase alpha chain TMP-TENI PF02581.12 KLO14206.1 - 0.045 12.8 0.3 2.2 7.3 0.0 2.5 2 0 0 2 2 2 0 Thiamine monophosphate synthase/TENI Img2 PF05046.9 KLO14208.1 - 7.2e-14 51.7 0.0 9.4e-14 51.4 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial large subunit ribosomal protein (Img2) Bot1p PF12298.3 KLO14211.1 - 5.1e-28 98.1 1.1 5.3e-28 98.0 0.1 1.5 2 0 0 2 2 2 1 Eukaryotic mitochondrial regulator protein MRP-L20 PF12824.2 KLO14211.1 - 0.0065 16.4 0.0 0.0065 16.4 0.0 2.0 3 0 0 3 3 3 1 Mitochondrial ribosomal protein subunit L20 Cyclin_N PF00134.18 KLO14212.1 - 1.1e-10 41.1 0.0 1.7e-09 37.3 0.0 2.4 2 1 0 2 2 2 1 Cyclin, N-terminal domain SRP54 PF00448.17 KLO14213.1 - 8.9e-48 162.3 0.1 3e-47 160.6 0.0 1.9 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain SRP-alpha_N PF04086.8 KLO14213.1 - 3.6e-45 154.5 3.7 4.9e-44 150.8 2.6 2.1 1 1 0 1 1 1 1 Signal recognition particle, alpha subunit, N-terminal CbiA PF01656.18 KLO14213.1 - 2.1e-07 30.5 0.1 4.4e-07 29.5 0.0 1.5 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain SRP54_N PF02881.14 KLO14213.1 - 1.2e-05 25.3 0.0 4.4e-05 23.4 0.0 2.0 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain ArgK PF03308.11 KLO14213.1 - 0.00016 20.5 0.0 0.00036 19.3 0.0 1.5 1 0 0 1 1 1 1 ArgK protein AAA_22 PF13401.1 KLO14213.1 - 0.0054 16.8 0.0 0.029 14.5 0.0 2.2 3 0 0 3 3 3 1 AAA domain MobB PF03205.9 KLO14213.1 - 0.006 16.2 0.0 0.021 14.5 0.0 1.9 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_30 PF13604.1 KLO14213.1 - 0.0062 16.1 0.0 0.013 15.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 KLO14213.1 - 0.03 14.3 0.1 0.25 11.3 0.0 2.4 2 0 0 2 2 2 0 AAA ATPase domain ArsA_ATPase PF02374.10 KLO14213.1 - 0.035 13.1 0.1 2.1 7.3 0.0 2.3 2 0 0 2 2 2 0 Anion-transporting ATPase NTPase_1 PF03266.10 KLO14213.1 - 0.037 13.7 0.0 0.15 11.7 0.0 2.1 1 1 0 1 1 1 0 NTPase Fer4_NifH PF00142.13 KLO14213.1 - 0.08 12.1 0.0 0.16 11.1 0.0 1.4 1 0 0 1 1 1 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family ADH_zinc_N PF00107.21 KLO14214.1 - 7.8e-16 57.8 0.1 4.9e-15 55.2 0.1 2.0 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KLO14214.1 - 7.6e-10 38.5 0.0 2.6e-09 36.8 0.0 1.8 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 KLO14214.1 - 7.3e-09 36.5 0.0 1.4e-08 35.6 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase NAD_binding_10 PF13460.1 KLO14214.1 - 0.074 13.0 0.4 0.11 12.4 0.3 1.3 1 0 0 1 1 1 0 NADH(P)-binding Got1 PF04178.7 KLO14215.1 - 5.5e-16 58.7 23.2 7e-16 58.3 16.1 1.1 1 0 0 1 1 1 1 Got1/Sft2-like family Lactamase_B PF00753.22 KLO14216.1 - 8.2e-28 97.3 1.4 1e-27 97.0 1.0 1.1 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily BcrAD_BadFG PF01869.15 KLO14216.1 - 0.00084 18.7 0.0 0.00092 18.5 0.0 1.2 1 0 0 1 1 1 1 BadF/BadG/BcrA/BcrD ATPase family Lactamase_B_2 PF12706.2 KLO14216.1 - 0.038 13.5 0.4 0.07 12.6 0.2 1.4 1 1 0 1 1 1 0 Beta-lactamase superfamily domain Rifin_STEVOR PF02009.11 KLO14217.1 - 0.0015 18.2 0.1 0.0031 17.1 0.1 1.5 1 1 0 1 1 1 1 Rifin/stevor family DUF1191 PF06697.7 KLO14217.1 - 0.009 14.8 0.0 0.013 14.3 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1191) Syndecan PF01034.15 KLO14217.1 - 0.038 13.6 0.5 0.089 12.4 0.4 1.6 1 0 0 1 1 1 0 Syndecan domain BatA PF07584.6 KLO14217.1 - 0.062 13.5 0.2 0.15 12.2 0.1 1.6 1 0 0 1 1 1 0 Aerotolerance regulator N-terminal EphA2_TM PF14575.1 KLO14217.1 - 0.07 13.5 0.0 0.14 12.5 0.0 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain FixQ PF05545.6 KLO14217.1 - 0.076 12.6 0.1 0.2 11.3 0.1 1.6 1 0 0 1 1 1 0 Cbb3-type cytochrome oxidase component FixQ P12 PF12669.2 KLO14217.1 - 0.57 10.4 2.9 1 9.6 2.0 1.3 1 0 0 1 1 1 0 Virus attachment protein p12 family Dicty_REP PF05086.7 KLO14217.1 - 3.8 5.1 4.7 4.6 4.8 3.2 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Phage_Coat_B PF05356.6 KLO14217.1 - 6.3 6.5 7.3 0.98 9.1 1.9 1.9 2 0 0 2 2 2 0 Phage Coat protein B DUF445 PF04286.7 KLO14218.1 - 0.35 10.3 9.1 0.6 9.5 6.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF445) Peptidase_C6 PF00851.13 KLO14218.1 - 4 5.9 5.9 0.48 9.0 0.1 1.9 2 0 0 2 2 2 0 Helper component proteinase Paramyxo_ncap PF00973.14 KLO14219.1 - 0.12 11.0 0.0 0.13 10.9 0.0 1.0 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein PPTA PF01239.17 KLO14220.1 - 4.9e-47 155.3 18.5 3.2e-10 38.9 0.7 6.2 7 0 0 7 7 7 5 Protein prenyltransferase alpha subunit repeat MetW PF07021.7 KLO14220.1 - 0.02 14.2 0.0 0.76 9.1 0.0 2.4 2 1 0 2 2 2 0 Methionine biosynthesis protein MetW DUF651 PF04895.7 KLO14220.1 - 0.063 12.9 0.9 0.36 10.4 0.0 2.3 2 0 0 2 2 2 0 Archaeal protein of unknown function (DUF651) DUF1455 PF07306.6 KLO14220.1 - 0.065 13.2 0.0 0.1 12.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1455) DUF4209 PF13910.1 KLO14220.1 - 0.13 12.3 0.1 0.24 11.5 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4209) TPR_14 PF13428.1 KLO14221.1 - 1.4e-09 37.7 8.2 2.4 9.0 0.2 11.0 12 1 1 13 13 13 1 Tetratricopeptide repeat Mad3_BUB1_I PF08311.7 KLO14221.1 - 0.00029 20.6 9.3 1.9 8.2 0.2 5.2 6 0 0 6 6 6 3 Mad3/BUB1 homology region 1 NRDE-2 PF08424.5 KLO14221.1 - 0.00062 18.7 4.9 0.37 9.6 0.1 4.4 3 2 2 5 5 5 2 NRDE-2, necessary for RNA interference TPR_12 PF13424.1 KLO14221.1 - 0.00083 19.2 14.2 0.99 9.3 0.0 6.7 5 2 1 7 7 7 2 Tetratricopeptide repeat TPR_7 PF13176.1 KLO14221.1 - 0.00099 18.7 4.6 19 5.3 0.0 7.2 7 1 0 7 7 7 0 Tetratricopeptide repeat TPR_19 PF14559.1 KLO14221.1 - 0.0012 19.1 4.2 1.2 9.5 0.1 5.4 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_2 PF07719.12 KLO14221.1 - 0.0022 17.7 16.5 0.21 11.5 0.0 8.1 9 0 0 9 9 9 1 Tetratricopeptide repeat TPR_16 PF13432.1 KLO14221.1 - 0.011 16.3 13.1 2.7 8.7 0.0 6.4 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_8 PF13181.1 KLO14221.1 - 0.019 14.7 4.8 2.3 8.1 0.0 5.0 5 0 0 5 5 5 0 Tetratricopeptide repeat NRN1 PF15056.1 KLO14222.1 - 0.0072 16.2 0.0 0.96 9.4 0.0 2.4 1 1 1 2 2 2 1 Neuritin protein family FlaC_arch PF05377.6 KLO14222.1 - 0.023 14.6 0.2 0.059 13.2 0.2 1.7 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) Prefoldin PF02996.12 KLO14222.1 - 0.038 13.6 0.2 0.3 10.7 0.1 2.2 2 0 0 2 2 2 0 Prefoldin subunit Prefoldin_2 PF01920.15 KLO14222.1 - 0.064 13.0 1.4 0.086 12.6 0.1 1.8 3 0 0 3 3 3 0 Prefoldin subunit WD40 PF00400.27 KLO14223.1 - 6.4e-23 79.7 11.8 4e-09 36.0 0.2 6.0 6 0 0 6 6 6 5 WD domain, G-beta repeat Nucleoporin_N PF08801.6 KLO14223.1 - 0.0076 15.0 0.0 0.38 9.4 0.0 2.7 2 1 1 3 3 3 1 Nup133 N terminal like NMO PF03060.10 KLO14224.1 - 1.6e-70 237.8 0.8 1.9e-70 237.6 0.6 1.1 1 0 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.20 KLO14224.1 - 4.7e-06 25.7 0.2 1.5e-05 24.0 0.1 1.9 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.13 KLO14224.1 - 0.075 11.8 1.0 0.14 11.0 0.7 1.4 1 0 0 1 1 1 0 FMN-dependent dehydrogenase Cyto_heme_lyase PF01265.12 KLO14226.1 - 4.8e-79 265.6 0.1 5.7e-79 265.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome c/c1 heme lyase Brix PF04427.13 KLO14227.1 - 8.9e-48 162.4 0.0 1.2e-47 162.1 0.0 1.1 1 0 0 1 1 1 1 Brix domain TFIIA PF03153.8 KLO14227.1 - 0.00044 20.2 18.5 0.00064 19.7 12.8 1.2 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit CENP-T PF15511.1 KLO14227.1 - 0.012 14.9 16.8 0.017 14.3 11.7 1.2 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T COPI_C PF06957.6 KLO14227.1 - 0.96 7.9 14.5 2.2 6.7 10.1 1.6 1 0 0 1 1 1 0 Coatomer (COPI) alpha subunit C-terminus DUF2514 PF10721.4 KLO14227.1 - 1.5 8.4 9.4 0.21 11.2 3.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2514) Nop25 PF09805.4 KLO14227.1 - 2 8.4 24.6 4.8 7.2 17.0 1.6 1 0 0 1 1 1 0 Nucleolar protein 12 (25kDa) Gpi1 PF05024.10 KLO14228.1 - 6.1e-43 146.7 14.7 1.3e-42 145.6 10.2 1.6 1 0 0 1 1 1 1 N-acetylglucosaminyl transferase component (Gpi1) FIST_C PF10442.4 KLO14228.1 - 0.05 13.5 0.0 0.09 12.7 0.0 1.3 1 0 0 1 1 1 0 FIST C domain F-box-like PF12937.2 KLO14232.1 - 1.5e-06 27.8 0.1 1.2e-05 24.9 0.0 2.5 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 KLO14232.1 - 0.0069 16.0 0.1 0.18 11.5 0.0 3.1 3 0 0 3 3 3 1 F-box domain F-box-like PF12937.2 KLO14233.1 - 9.3e-05 22.0 1.8 0.00022 20.8 0.2 2.6 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 KLO14233.1 - 0.00022 20.7 0.1 0.0015 18.1 0.0 2.4 3 0 0 3 3 3 1 F-box domain LRR_4 PF12799.2 KLO14233.1 - 3.8 7.2 7.3 6.6 6.4 0.3 4.2 4 1 1 5 5 5 0 Leucine Rich repeats (2 copies) Methyltransf_31 PF13847.1 KLO14234.1 - 6.2e-15 55.0 0.1 8.9e-15 54.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 KLO14234.1 - 3.3e-11 42.8 0.0 4.9e-11 42.2 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_18 PF12847.2 KLO14234.1 - 6.8e-11 42.7 0.0 1.3e-10 41.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KLO14234.1 - 3.2e-10 40.3 0.0 6.9e-10 39.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KLO14234.1 - 4.1e-09 36.5 0.0 2.3e-08 34.0 0.0 2.2 3 0 0 3 3 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 KLO14234.1 - 2.6e-08 33.7 0.0 5.3e-08 32.7 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KLO14234.1 - 3.5e-08 33.0 0.1 5.8e-08 32.2 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_9 PF08003.6 KLO14234.1 - 6.4e-07 28.3 0.0 9.5e-07 27.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) CMAS PF02353.15 KLO14234.1 - 2e-06 27.0 0.0 2.7e-06 26.6 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_12 PF08242.7 KLO14234.1 - 4.3e-06 27.1 0.0 9.4e-06 26.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KLO14234.1 - 6.2e-06 26.5 0.0 1.1e-05 25.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 KLO14234.1 - 2.1e-05 24.1 0.1 5.5e-05 22.7 0.0 1.6 2 0 0 2 2 2 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) PRMT5 PF05185.11 KLO14234.1 - 0.00017 20.6 0.0 0.00024 20.1 0.0 1.2 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase FtsJ PF01728.14 KLO14234.1 - 0.00023 21.1 0.0 0.00038 20.4 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase Ubie_methyltran PF01209.13 KLO14234.1 - 0.00038 19.6 0.0 0.00056 19.0 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_16 PF10294.4 KLO14234.1 - 0.0005 19.5 0.1 0.0008 18.8 0.1 1.3 1 0 0 1 1 1 1 Putative methyltransferase TehB PF03848.9 KLO14234.1 - 0.00081 18.6 0.1 0.0029 16.8 0.1 1.8 1 1 0 1 1 1 1 Tellurite resistance protein TehB Methyltransf_32 PF13679.1 KLO14234.1 - 0.0019 17.8 0.0 0.003 17.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_24 PF13578.1 KLO14234.1 - 0.016 16.0 0.0 0.032 15.0 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Cons_hypoth95 PF03602.10 KLO14234.1 - 0.023 14.0 0.0 0.034 13.5 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical protein 95 UPF0020 PF01170.13 KLO14234.1 - 0.078 12.5 0.1 0.15 11.6 0.0 1.3 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 F-box-like PF12937.2 KLO14236.1 - 5.7e-07 29.1 0.2 1.7e-06 27.6 0.1 1.9 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KLO14236.1 - 7.5e-07 28.6 0.0 2.8e-06 26.8 0.0 2.0 1 0 0 1 1 1 1 F-box domain F-box PF00646.28 KLO14237.1 - 2.8e-07 30.0 0.6 1.4e-06 27.7 0.4 2.3 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 KLO14237.1 - 6.1e-06 25.8 1.6 6.1e-06 25.8 1.1 2.6 2 0 0 2 2 2 1 F-box-like F-box-like_2 PF13013.1 KLO14237.1 - 0.00015 21.4 1.1 0.021 14.5 0.2 2.6 2 0 0 2 2 2 2 F-box-like domain LRR_8 PF13855.1 KLO14237.1 - 0.00029 20.5 4.1 0.64 9.8 0.0 4.2 5 0 0 5 5 5 2 Leucine rich repeat LRR_4 PF12799.2 KLO14237.1 - 0.014 14.9 2.3 1.2 8.8 0.1 4.5 3 1 1 4 4 4 0 Leucine Rich repeats (2 copies) Aldo_ket_red PF00248.16 KLO14238.1 - 1.5e-34 119.1 0.0 1.9e-34 118.8 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Pterin_4a PF01329.14 KLO14239.1 - 7.8e-12 44.7 0.0 1.2e-11 44.1 0.0 1.3 1 0 0 1 1 1 1 Pterin 4 alpha carbinolamine dehydratase GHMP_kinases_N PF00288.21 KLO14240.1 - 1.6e-09 37.6 4.6 1.9e-09 37.4 2.1 1.9 2 0 0 2 2 2 1 GHMP kinases N terminal domain Exo_endo_phos PF03372.18 KLO14242.1 - 1.2e-20 74.4 0.1 1.7e-20 74.0 0.1 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family LRR_4 PF12799.2 KLO14242.1 - 2.3e-16 59.0 12.1 5.1e-09 35.5 2.4 2.4 2 0 0 2 2 2 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KLO14242.1 - 2.3e-09 36.8 10.6 8.8e-06 25.3 1.3 2.5 1 1 1 2 2 2 2 Leucine rich repeat LRR_1 PF00560.28 KLO14242.1 - 5.6e-08 31.7 9.4 0.11 12.5 0.2 4.8 4 0 0 4 4 4 3 Leucine Rich Repeat LRR_7 PF13504.1 KLO14242.1 - 0.097 12.9 12.7 2.1 8.9 0.4 4.6 4 0 0 4 4 4 0 Leucine rich repeat LRR_6 PF13516.1 KLO14242.1 - 0.36 11.0 5.5 28 5.1 0.0 3.8 3 0 0 3 3 3 0 Leucine Rich repeat Sensor PF13796.1 KLO14243.1 - 9e-10 38.4 8.6 9e-10 38.4 5.9 2.0 2 0 0 2 2 2 1 Putative sensor Voltage_CLC PF00654.15 KLO14244.1 - 1.4e-95 320.3 19.2 6e-95 318.2 12.2 2.0 2 0 0 2 2 2 2 Voltage gated chloride channel Zn_clus PF00172.13 KLO14245.1 - 1.7e-08 34.2 14.0 3.3e-08 33.2 9.7 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MMtag PF10159.4 KLO14246.1 - 9.2e-31 105.7 3.8 9.2e-31 105.7 2.6 2.6 2 0 0 2 2 2 1 Kinase phosphorylation protein Dsh_C PF12316.3 KLO14246.1 - 3.9 7.5 11.2 6.1 6.9 7.8 1.3 1 0 0 1 1 1 0 Segment polarity protein dishevelled (Dsh) C terminal FLO_LFY PF01698.11 KLO14246.1 - 5.8 5.6 12.0 7.3 5.3 8.3 1.1 1 0 0 1 1 1 0 Floricaula / Leafy protein DUF566 PF04484.7 KLO14246.1 - 9.1 5.6 13.2 12 5.2 9.2 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF566) Topoisom_bac PF01131.15 KLO14247.1 - 4.4e-95 318.8 0.0 5.5e-95 318.5 0.0 1.1 1 0 0 1 1 1 1 DNA topoisomerase zf-GRF PF06839.7 KLO14247.1 - 3.3e-21 74.9 14.6 2.3e-12 46.6 3.0 2.8 2 0 0 2 2 2 2 GRF zinc finger zf-CCHC PF00098.18 KLO14247.1 - 4.4e-21 73.7 38.8 1.9e-05 24.3 2.6 4.7 4 0 0 4 4 4 4 Zinc knuckle Toprim PF01751.17 KLO14247.1 - 1.4e-19 69.9 0.0 2.7e-19 68.9 0.0 1.5 1 0 0 1 1 1 1 Toprim domain zf-CCHC_3 PF13917.1 KLO14247.1 - 8.6e-11 41.3 18.4 0.024 14.3 0.3 4.6 4 0 0 4 4 4 4 Zinc knuckle GAS PF13851.1 KLO14247.1 - 0.2 10.8 0.1 0.41 9.8 0.1 1.4 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding TraF_2 PF13729.1 KLO14248.1 - 0.26 10.0 0.4 0.49 9.1 0.3 1.4 1 0 0 1 1 1 0 F plasmid transfer operon, TraF, protein PP2C PF00481.16 KLO14249.1 - 6.9e-23 81.3 0.0 2.4e-21 76.2 0.0 2.1 1 1 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.1 KLO14249.1 - 4.8e-08 32.6 0.0 1.8e-07 30.8 0.0 1.9 1 1 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.7 KLO14249.1 - 0.011 15.4 0.2 0.66 9.6 0.0 2.7 2 2 0 2 2 2 0 Stage II sporulation protein E (SpoIIE) DUF1253 PF06862.7 KLO14253.1 - 4.1e-145 483.5 0.3 5e-145 483.3 0.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1253) DUF4112 PF13430.1 KLO14254.1 - 5.1e-30 103.5 0.1 6.6e-30 103.1 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4112) BLVR PF06375.6 KLO14254.1 - 1.4 8.6 7.0 1.4 8.7 1.7 2.1 2 0 0 2 2 2 0 Bovine leukaemia virus receptor (BLVR) DUF4066 PF13278.1 KLO14256.1 - 8e-26 90.2 0.0 9e-26 90.1 0.0 1.1 1 0 0 1 1 1 1 Putative amidotransferase DJ-1_PfpI PF01965.19 KLO14256.1 - 8.4e-18 64.2 0.0 1e-17 63.9 0.0 1.1 1 0 0 1 1 1 1 DJ-1/PfpI family Oxidored_q6 PF01058.17 KLO14256.1 - 0.0026 17.3 0.0 0.005 16.4 0.0 1.4 1 1 0 1 1 1 1 NADH ubiquinone oxidoreductase, 20 Kd subunit TFIID_20kDa PF03847.8 KLO14257.1 - 4.8e-29 100.4 0.4 9e-29 99.5 0.3 1.5 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A CBFD_NFYB_HMF PF00808.18 KLO14257.1 - 0.0032 17.4 0.0 0.0096 15.9 0.0 1.9 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone SPRR2 PF14820.1 KLO14257.1 - 0.014 15.2 6.2 0.026 14.3 4.3 1.4 1 0 0 1 1 1 0 Small proline-rich 2 YtzH PF14165.1 KLO14257.1 - 0.27 11.5 6.1 2.5 8.3 3.3 2.2 2 0 0 2 2 2 0 YtzH-like protein Pex19 PF04614.7 KLO14257.1 - 0.54 9.8 5.0 0.55 9.8 2.6 1.8 2 1 0 2 2 2 0 Pex19 protein family MSA-2c PF12238.3 KLO14257.1 - 1 8.9 4.9 3 7.4 3.4 1.9 1 0 0 1 1 1 0 Merozoite surface antigen 2c Lin-8 PF03353.10 KLO14257.1 - 5 6.3 5.6 8.8 5.5 3.9 1.4 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist DUF3455 PF11937.3 KLO14258.1 - 8.5e-24 84.4 0.0 1.2e-23 83.9 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3455) Arylesterase PF01731.15 KLO14259.1 - 7.1e-07 29.1 0.0 6.1e-06 26.1 0.0 2.3 2 0 0 2 2 2 1 Arylesterase Reg_prop PF07494.6 KLO14259.1 - 0.0049 16.7 0.0 5.3 7.4 0.0 3.1 3 0 0 3 3 3 2 Two component regulator propeller MNHE PF01899.11 KLO14259.1 - 0.068 12.7 0.0 0.15 11.7 0.0 1.5 1 0 0 1 1 1 0 Na+/H+ ion antiporter subunit HAD_2 PF13419.1 KLO14260.1 - 9.4e-21 74.8 0.0 1.4e-20 74.2 0.0 1.3 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 KLO14260.1 - 3.7e-09 36.1 0.0 1.1e-08 34.6 0.0 1.9 1 1 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.21 KLO14260.1 - 4.5e-08 33.7 0.0 8.5e-08 32.8 0.0 1.5 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase F-box-like PF12937.2 KLO14261.1 - 6.7e-06 25.7 0.0 2.9e-05 23.7 0.0 2.2 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KLO14261.1 - 0.041 13.5 1.1 0.15 11.7 0.0 2.5 2 0 0 2 2 2 0 F-box domain WLM PF08325.5 KLO14262.1 - 1e-45 155.8 0.0 1.4e-45 155.4 0.0 1.2 1 0 0 1 1 1 1 WLM domain zf-RanBP PF00641.13 KLO14262.1 - 2.1e-09 36.2 12.5 3.6e-06 25.9 1.4 3.6 3 1 0 3 3 3 2 Zn-finger in Ran binding protein and others DUF45 PF01863.12 KLO14262.1 - 0.00046 20.0 0.2 0.00078 19.2 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function DUF45 DZR PF12773.2 KLO14262.1 - 0.0099 15.6 18.4 0.049 13.4 6.4 2.5 2 0 0 2 2 2 2 Double zinc ribbon Stc1 PF12898.2 KLO14262.1 - 0.079 13.0 10.8 0.39 10.8 0.1 3.3 2 1 0 2 2 2 0 Stc1 domain PALP PF00291.20 KLO14263.1 - 3.6e-74 249.7 0.0 4.4e-74 249.4 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Thr_dehydrat_C PF00585.13 KLO14263.1 - 2.8e-44 148.6 0.2 5.8e-27 93.1 0.0 2.3 2 0 0 2 2 2 2 C-terminal regulatory domain of Threonine dehydratase DUF3609 PF12259.3 KLO14265.1 - 0.0035 16.0 0.0 0.004 15.8 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3609) DUF3753 PF12575.3 KLO14265.1 - 0.011 15.5 0.3 0.018 14.8 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3753) DUF4395 PF14340.1 KLO14265.1 - 0.014 15.4 0.0 0.019 15.0 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4395) Tetraspannin PF00335.15 KLO14265.1 - 0.047 12.9 0.2 0.059 12.6 0.2 1.1 1 0 0 1 1 1 0 Tetraspanin family Frizzled PF01534.12 KLO14265.1 - 0.051 12.3 0.0 0.056 12.2 0.0 1.1 1 0 0 1 1 1 0 Frizzled/Smoothened family membrane region SIT PF15330.1 KLO14265.1 - 0.064 13.4 0.0 0.18 11.9 0.0 1.7 2 0 0 2 2 2 0 SHP2-interacting transmembrane adaptor protein, SIT Shisa PF13908.1 KLO14265.1 - 0.074 13.2 0.0 0.09 12.9 0.0 1.2 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator DUF202 PF02656.10 KLO14265.1 - 0.091 12.9 0.3 0.13 12.4 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF202) TMEM154 PF15102.1 KLO14265.1 - 0.098 12.3 0.0 0.12 12.0 0.0 1.2 1 0 0 1 1 1 0 TMEM154 protein family SCIMP PF15050.1 KLO14265.1 - 0.1 12.4 0.5 0.14 12.0 0.4 1.4 1 1 0 1 1 1 0 SCIMP protein DUF1275 PF06912.6 KLO14266.1 - 0.0063 15.7 0.6 0.0077 15.4 0.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1275) Choline_transpo PF04515.7 KLO14266.1 - 0.011 14.5 1.0 0.013 14.2 0.7 1.1 1 0 0 1 1 1 0 Plasma-membrane choline transporter Cytomega_TRL10 PF06084.6 KLO14266.1 - 0.02 14.7 0.1 0.026 14.3 0.0 1.2 1 0 0 1 1 1 0 Cytomegalovirus TRL10 protein CD34_antigen PF06365.7 KLO14267.1 - 0.0024 17.5 0.0 0.0077 15.9 0.0 1.6 1 1 1 2 2 2 1 CD34/Podocalyxin family TMEM192 PF14802.1 KLO14267.1 - 0.023 13.5 0.0 0.025 13.4 0.0 1.1 1 0 0 1 1 1 0 TMEM192 family COG2 PF06148.6 KLO14268.1 - 5.9e-30 103.8 0.5 5.9e-30 103.8 0.3 2.3 2 0 0 2 2 2 1 COG (conserved oligomeric Golgi) complex component, COG2 DUF3510 PF12022.3 KLO14268.1 - 9.4e-19 67.7 0.0 3.8e-18 65.7 0.0 2.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3510) DFF-C PF09033.5 KLO14268.1 - 7.2e-05 22.6 2.5 0.00052 19.8 0.1 3.0 3 0 0 3 3 3 1 DNA Fragmentation factor 45kDa, C terminal domain Vps51 PF08700.6 KLO14268.1 - 0.00089 19.0 1.3 0.016 15.0 0.0 3.5 3 1 0 4 4 4 1 Vps51/Vps67 Vps8 PF12816.2 KLO14269.1 - 5.2e-60 202.0 0.2 1.2e-58 197.6 0.0 2.5 2 0 0 2 2 2 1 Golgi CORVET complex core vacuolar protein 8 Clathrin PF00637.15 KLO14269.1 - 0.0054 16.3 0.1 3.2 7.3 0.0 3.0 3 0 0 3 3 3 2 Region in Clathrin and VPS PQQ_3 PF13570.1 KLO14269.1 - 0.058 13.6 0.5 0.25 11.6 0.1 2.3 2 0 0 2 2 2 0 PQQ-like domain PHD PF00628.24 KLO14270.1 - 1.9e-12 46.6 7.7 3.2e-12 45.9 5.4 1.4 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.1 KLO14270.1 - 0.31 10.3 2.4 0.56 9.5 1.7 1.4 1 0 0 1 1 1 0 PHD-finger PX PF00787.19 KLO14271.1 - 1.1e-27 96.0 0.6 4.3e-27 94.1 0.1 1.8 1 1 1 2 2 2 1 PX domain DUF1792 PF08759.6 KLO14271.1 - 0.057 13.0 0.1 0.075 12.6 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1792) Sec34 PF04136.10 KLO14272.1 - 3.9e-33 114.3 0.1 8.2e-33 113.3 0.0 1.6 1 0 0 1 1 1 1 Sec34-like family DUF848 PF05852.6 KLO14272.1 - 0.3 10.9 2.5 0.38 10.5 0.5 2.1 2 1 0 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) Serglycin PF04360.7 KLO14274.1 - 3.3 7.4 7.1 7.3 6.3 4.9 1.6 1 1 0 1 1 1 0 Serglycin Melibiase PF02065.13 KLO14275.1 - 1.1e-24 86.8 0.4 3.4e-20 72.1 0.0 2.7 2 1 1 3 3 3 2 Melibiase Raffinose_syn PF05691.7 KLO14275.1 - 0.046 11.2 0.0 0.069 10.6 0.0 1.2 1 0 0 1 1 1 0 Raffinose synthase or seed imbibition protein Sip1 DUF1484 PF07363.6 KLO14276.1 - 0.035 14.4 0.6 0.11 12.8 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1484) DUF4083 PF13314.1 KLO14276.1 - 0.79 9.5 1.1 7.6 6.4 0.0 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4083) Baculo_PEP_C PF04513.7 KLO14276.1 - 2.5 7.9 10.6 15 5.4 0.0 4.2 4 1 0 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus TMF_TATA_bd PF12325.3 KLO14277.1 - 0.022 14.4 1.7 0.026 14.2 1.2 1.2 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding Lipoprotein_16 PF03923.8 KLO14277.1 - 0.026 13.8 0.1 0.029 13.7 0.1 1.1 1 0 0 1 1 1 0 Uncharacterized lipoprotein TAFH PF07531.9 KLO14277.1 - 0.027 14.1 0.6 0.033 13.8 0.4 1.1 1 0 0 1 1 1 0 NHR1 homology to TAF FlxA PF14282.1 KLO14277.1 - 0.041 13.8 0.9 0.043 13.7 0.6 1.2 1 0 0 1 1 1 0 FlxA-like protein TMF_DNA_bd PF12329.3 KLO14277.1 - 0.071 12.9 0.2 0.085 12.6 0.2 1.2 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding ACCA PF03255.9 KLO14277.1 - 0.087 12.3 1.1 0.11 12.0 0.8 1.0 1 0 0 1 1 1 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit Ax_dynein_light PF10211.4 KLO14277.1 - 0.09 12.6 2.3 0.094 12.5 1.6 1.0 1 0 0 1 1 1 0 Axonemal dynein light chain SlyX PF04102.7 KLO14277.1 - 0.15 12.4 1.3 0.22 11.9 0.9 1.4 1 1 0 1 1 1 0 SlyX HSP9_HSP12 PF04119.7 KLO14278.1 - 2.4e-22 78.7 3.8 2.4e-22 78.7 2.6 1.7 2 0 0 2 2 2 1 Heat shock protein 9/12 DUF3484 PF11983.3 KLO14278.1 - 0.0043 17.8 0.3 0.1 13.4 0.0 2.0 1 1 1 2 2 2 1 Domain of unknown function (DUF3484) MT0933_antitox PF14013.1 KLO14278.1 - 0.92 9.6 6.3 1.2e+02 2.9 4.4 2.6 1 1 0 1 1 1 0 MT0933-like antitoxin protein Pro-rich PF15240.1 KLO14279.1 - 0.1 12.6 9.9 0.1 12.6 6.8 1.1 1 0 0 1 1 1 0 Proline-rich LSM PF01423.17 KLO14280.1 - 1.6e-12 46.7 0.3 2.3e-12 46.2 0.2 1.2 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 KLO14280.1 - 0.014 15.3 0.0 0.021 14.7 0.0 1.3 1 0 0 1 1 1 0 Ataxin 2 SM domain E3_binding PF02817.12 KLO14280.1 - 0.023 14.3 0.0 0.045 13.4 0.0 1.5 1 0 0 1 1 1 0 e3 binding domain LSM14 PF12701.2 KLO14280.1 - 0.089 12.6 0.0 0.13 12.1 0.0 1.2 1 0 0 1 1 1 0 Scd6-like Sm domain PAPA-1 PF04795.7 KLO14281.1 - 1.1e-16 61.2 0.2 1.1e-16 61.2 0.1 3.1 2 1 1 3 3 3 1 PAPA-1-like conserved region zf-RING_2 PF13639.1 KLO14282.1 - 1.5e-13 50.3 4.8 2.5e-13 49.6 3.4 1.4 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 KLO14282.1 - 2.3e-07 30.8 0.8 4.6e-07 29.8 0.6 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_5 PF14634.1 KLO14282.1 - 7e-06 25.6 2.6 1.2e-05 24.9 1.8 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 KLO14282.1 - 1.2e-05 25.1 4.3 2.2e-05 24.3 3.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 KLO14282.1 - 3.8e-05 23.4 1.4 7.5e-05 22.5 1.0 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4 PF00097.20 KLO14282.1 - 0.0002 20.9 2.4 0.00035 20.1 1.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.1 KLO14282.1 - 0.00057 19.4 2.4 0.00097 18.6 1.7 1.4 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-C3HC4_3 PF13920.1 KLO14282.1 - 0.00062 19.3 1.6 0.0011 18.6 1.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) FANCL_C PF11793.3 KLO14282.1 - 0.0091 15.9 1.5 0.022 14.6 1.0 1.7 1 1 0 1 1 1 1 FANCL C-terminal domain RINGv PF12906.2 KLO14282.1 - 0.0099 15.9 2.4 0.018 15.0 1.6 1.5 1 0 0 1 1 1 1 RING-variant domain Prok-RING_4 PF14447.1 KLO14282.1 - 3.1 7.4 6.1 9.7 5.8 2.0 2.4 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 zf-MIZ PF02891.15 KLO14282.1 - 3.3 7.2 8.6 11 5.6 6.0 1.8 1 1 0 1 1 1 0 MIZ/SP-RING zinc finger Aminotran_3 PF00202.16 KLO14283.1 - 9.1e-105 350.2 0.0 1.1e-104 349.9 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.16 KLO14283.1 - 7.5e-06 25.1 0.0 8.5e-05 21.6 0.0 2.0 2 0 0 2 2 2 1 Aminotransferase class I and II 2OG-FeII_Oxy_2 PF13532.1 KLO14284.1 - 4.2e-19 69.1 0.0 8.8e-19 68.0 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily ATP-synt_DE_N PF02823.11 KLO14285.1 - 8.8e-20 70.2 0.2 1.3e-19 69.7 0.2 1.3 1 0 0 1 1 1 1 ATP synthase, Delta/Epsilon chain, beta-sandwich domain Abhydrolase_3 PF07859.8 KLO14286.1 - 2e-15 56.9 0.0 3.3e-15 56.2 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KLO14286.1 - 2e-09 37.3 0.0 3e-09 36.7 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KLO14286.1 - 8.8e-06 25.7 0.5 1.4e-05 25.0 0.3 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 KLO14286.1 - 9.4e-06 24.9 0.0 0.0076 15.4 0.0 2.8 2 1 0 2 2 2 2 Prolyl oligopeptidase family Chlorophyllase2 PF12740.2 KLO14286.1 - 4.8e-05 22.3 0.0 6.5e-05 21.9 0.0 1.1 1 0 0 1 1 1 1 Chlorophyllase enzyme COesterase PF00135.23 KLO14286.1 - 0.0019 17.0 0.0 0.077 11.6 0.0 2.0 2 0 0 2 2 2 1 Carboxylesterase family Chlorophyllase PF07224.6 KLO14286.1 - 0.032 13.0 0.0 0.044 12.5 0.0 1.1 1 0 0 1 1 1 0 Chlorophyllase AXE1 PF05448.7 KLO14286.1 - 0.18 10.2 0.0 1.6 7.1 0.0 2.3 2 0 0 2 2 2 0 Acetyl xylan esterase (AXE1) His_Phos_1 PF00300.17 KLO14287.1 - 1.5e-15 57.6 0.0 2e-15 57.2 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) GCS PF03074.11 KLO14288.1 - 2.7e-167 556.4 0.0 1.3e-135 452.2 0.0 2.1 2 0 0 2 2 2 2 Glutamate-cysteine ligase GCS2 PF04107.8 KLO14288.1 - 0.016 14.3 0.0 0.042 12.9 0.0 1.6 2 0 0 2 2 2 0 Glutamate-cysteine ligase family 2(GCS2) APG6 PF04111.7 KLO14289.1 - 4.8e-111 370.7 0.6 6e-111 370.4 0.4 1.1 1 0 0 1 1 1 1 Autophagy protein Apg6 V_ATPase_I PF01496.14 KLO14289.1 - 0.042 11.7 3.2 0.055 11.3 2.2 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family CAP59_mtransfer PF11735.3 KLO14289.1 - 0.11 11.6 0.9 0.2 10.8 0.6 1.3 1 0 0 1 1 1 0 Cryptococcal mannosyltransferase 1 TBPIP PF07106.8 KLO14289.1 - 0.18 11.3 8.7 0.42 10.1 6.0 1.6 1 0 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Vpu PF00558.14 KLO14289.1 - 0.23 11.0 3.0 1.3 8.6 0.0 2.5 2 0 0 2 2 2 0 Vpu protein HAUS-augmin3 PF14932.1 KLO14289.1 - 0.31 10.1 12.6 0.52 9.4 8.7 1.2 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 DUF4200 PF13863.1 KLO14289.1 - 0.33 10.9 23.0 0.65 9.9 15.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) IncA PF04156.9 KLO14289.1 - 1.1 8.7 17.0 2.1 7.9 11.8 1.4 1 0 0 1 1 1 0 IncA protein FtsL PF04999.8 KLO14289.1 - 1.1 8.9 6.9 1.4 8.6 3.8 1.9 1 1 1 2 2 2 0 Cell division protein FtsL DUF342 PF03961.8 KLO14289.1 - 7.2 4.9 10.3 10 4.4 7.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) IMS PF00817.15 KLO14290.1 - 6.5e-44 149.3 0.0 1.3e-43 148.3 0.0 1.5 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.3 KLO14290.1 - 2.1e-14 53.5 0.2 4.9e-14 52.3 0.1 1.6 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.3 KLO14290.1 - 2e-06 27.5 0.0 4.5e-06 26.3 0.0 1.7 1 0 0 1 1 1 1 IMS family HHH motif Cys_rich_CWC PF14375.1 KLO14290.1 - 0.13 12.1 0.4 0.26 11.2 0.3 1.5 1 0 0 1 1 1 0 Cysteine-rich CWC Methyltransf_6 PF03737.10 KLO14291.1 - 3.1e-25 88.8 2.6 1.4e-23 83.4 1.8 2.1 1 1 0 1 1 1 1 Demethylmenaquinone methyltransferase Ubiq_cyt_C_chap PF03981.7 KLO14293.1 - 4.1e-24 85.0 0.0 7.1e-22 77.7 0.0 3.0 1 1 0 1 1 1 1 Ubiquinol-cytochrome C chaperone MS_channel PF00924.13 KLO14294.1 - 5.8e-21 74.7 0.2 5.8e-21 74.7 0.1 1.7 2 0 0 2 2 2 1 Mechanosensitive ion channel EF-hand_6 PF13405.1 KLO14294.1 - 0.048 13.5 0.6 0.14 12.1 0.0 2.1 2 0 0 2 2 2 0 EF-hand domain GldM_C PF12080.3 KLO14294.1 - 0.13 12.2 0.1 0.57 10.1 0.1 2.0 1 1 1 2 2 2 0 GldM C-terminal domain MS_channel PF00924.13 KLO14295.1 - 1.5e-23 83.2 1.0 3.1e-23 82.1 0.7 1.5 1 0 0 1 1 1 1 Mechanosensitive ion channel EF-hand_1 PF00036.27 KLO14295.1 - 2.5e-05 23.2 1.0 2.5e-05 23.2 0.7 2.5 2 0 0 2 2 2 1 EF hand EF-hand_6 PF13405.1 KLO14295.1 - 0.00013 21.5 0.4 0.00013 21.5 0.3 2.6 2 0 0 2 2 2 1 EF-hand domain EF-hand_5 PF13202.1 KLO14295.1 - 0.00032 19.9 0.2 0.00032 19.9 0.1 2.6 2 0 0 2 2 2 1 EF hand EF-hand_7 PF13499.1 KLO14295.1 - 0.0042 17.2 0.2 0.0042 17.2 0.2 2.1 2 0 0 2 2 2 1 EF-hand domain pair SNARE PF05739.14 KLO14297.1 - 5.2e-18 64.5 2.1 1.3e-17 63.2 1.5 1.7 1 0 0 1 1 1 1 SNARE domain Syntaxin PF00804.20 KLO14297.1 - 2.3e-08 34.1 1.7 3e-06 27.3 0.0 3.0 2 1 0 2 2 2 1 Syntaxin MCPsignal PF00015.16 KLO14297.1 - 0.088 12.3 0.6 2 7.9 0.1 2.3 2 1 0 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain POTRA_2 PF08479.6 KLO14297.1 - 0.15 11.6 0.6 7.7 6.2 0.1 3.0 3 1 0 3 3 3 0 POTRA domain, ShlB-type Tmemb_9 PF05434.6 KLO14298.1 - 0.074 12.7 4.0 0.09 12.5 2.7 1.2 1 0 0 1 1 1 0 TMEM9 Arrestin_C PF02752.17 KLO14299.1 - 0.00028 20.9 0.0 0.00036 20.6 0.0 1.1 1 0 0 1 1 1 1 Arrestin (or S-antigen), C-terminal domain DUF2024 PF09630.5 KLO14299.1 - 0.087 12.5 0.2 0.17 11.5 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF2024) Ribosomal_S8 PF00410.14 KLO14300.1 - 1.1e-16 60.8 0.0 2e-16 60.0 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S8 Aldose_epim PF01263.15 KLO14301.1 - 1e-62 211.9 0.1 1.1e-62 211.8 0.1 1.0 1 0 0 1 1 1 1 Aldose 1-epimerase SIN1 PF05422.7 KLO14302.1 - 1.9e-12 46.4 0.0 2.5e-12 46.1 0.0 1.1 1 0 0 1 1 1 1 Stress-activated map kinase interacting protein 1 (SIN1) Sec3-PIP2_bind PF15277.1 KLO14302.1 - 0.041 13.7 0.0 0.061 13.1 0.0 1.4 1 1 0 1 1 1 0 Exocyst complex component SEC3 N-terminal PIP2 binding PH Tantalus PF15386.1 KLO14304.1 - 0.079 12.7 0.0 0.14 11.9 0.0 1.4 1 0 0 1 1 1 0 Drosophila Tantalus-like CheR_N PF03705.10 KLO14305.1 - 0.052 12.9 0.1 0.099 12.0 0.0 1.5 1 0 0 1 1 1 0 CheR methyltransferase, all-alpha domain DUF2126 PF09899.4 KLO14315.1 - 0.061 11.3 0.1 0.087 10.8 0.1 1.1 1 0 0 1 1 1 0 Putative amidoligase enzyme (DUF2126) Cnd3 PF12719.2 KLO14315.1 - 0.11 11.4 0.0 0.17 10.8 0.0 1.2 1 0 0 1 1 1 0 Nuclear condensing complex subunits, C-term domain DUF1219 PF06755.7 KLO14320.1 - 0.13 11.7 0.0 0.25 10.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1219) NAD_binding_11 PF14833.1 KLO14322.1 - 0.16 12.0 0.0 0.24 11.4 0.0 1.2 1 0 0 1 1 1 0 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase Herpes_PAP PF03325.8 KLO14326.1 - 0.14 11.6 0.6 0.29 10.6 0.3 1.5 2 0 0 2 2 2 0 Herpesvirus polymerase accessory protein DUF3518 PF12031.3 KLO14327.1 - 0.15 10.8 0.1 0.21 10.3 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3518) Mu-conotoxin PF05374.7 KLO14331.1 - 0.041 13.6 4.1 0.07 12.9 2.8 1.4 1 0 0 1 1 1 0 Mu-Conotoxin Cation_efflux PF01545.16 KLO14333.1 - 8.3e-06 25.0 8.6 2.4e-05 23.5 6.0 1.6 1 1 0 1 1 1 1 Cation efflux family DUF898 PF05987.8 KLO14333.1 - 0.016 14.1 0.9 0.025 13.4 0.7 1.3 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF898) MFS_1 PF07690.11 KLO14334.1 - 2.8e-40 138.1 49.3 4.7e-39 134.0 33.4 2.7 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KLO14334.1 - 5.9e-09 35.0 5.0 5.9e-09 35.0 3.5 2.5 2 1 0 2 2 2 1 Sugar (and other) transporter RicinB_lectin_2 PF14200.1 KLO14335.1 - 4.5e-08 33.4 4.1 0.00013 22.3 0.3 3.4 1 1 3 4 4 4 4 Ricin-type beta-trefoil lectin domain-like Ricin_B_lectin PF00652.17 KLO14335.1 - 0.0087 16.0 0.1 4.7 7.2 0.1 3.2 2 1 1 3 3 3 2 Ricin-type beta-trefoil lectin domain Adeno_E3_14_5 PF04834.7 KLO14339.1 - 0.47 10.9 0.1 0.47 10.9 0.1 1.9 2 1 1 3 3 3 0 Early E3 14.5 kDa protein DUF21 PF01595.15 KLO14339.1 - 0.79 8.9 7.4 1 8.6 5.1 1.1 1 0 0 1 1 1 0 Domain of unknown function DUF21 AA_permease PF00324.16 KLO14340.1 - 1.6e-117 392.7 31.0 2e-117 392.4 21.5 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 KLO14340.1 - 4.5e-35 121.0 33.1 4.5e-35 121.0 22.9 1.4 1 1 1 2 2 2 2 Amino acid permease DUF454 PF04304.8 KLO14344.1 - 0.47 10.5 0.0 0.47 10.5 0.0 3.9 4 0 0 4 4 4 0 Protein of unknown function (DUF454) DUF4199 PF13858.1 KLO14345.1 - 4 7.3 9.0 6.7 6.6 0.0 3.6 3 1 0 3 3 3 0 Protein of unknown function (DUF4199) Mito_carr PF00153.22 KLO14346.1 - 4.9e-29 99.8 2.1 3.4e-15 55.5 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein TRAPPC-Trs85 PF12739.2 KLO14347.1 - 0.0055 15.4 0.2 0.0065 15.1 0.1 1.1 1 0 0 1 1 1 1 ER-Golgi trafficking TRAPP I complex 85 kDa subunit DASH_Duo1 PF08651.5 KLO14347.1 - 0.0065 16.0 0.4 0.061 12.9 0.1 2.5 2 0 0 2 2 2 1 DASH complex subunit Duo1 Chal_sti_synt_N PF00195.14 KLO14347.1 - 0.032 13.4 5.1 0.15 11.3 1.8 2.0 1 1 1 2 2 2 0 Chalcone and stilbene synthases, N-terminal domain Phasin PF05597.6 KLO14347.1 - 0.074 12.8 10.0 0.36 10.5 1.1 2.4 1 1 0 2 2 2 0 Poly(hydroxyalcanoate) granule associated protein (phasin) Sec20 PF03908.8 KLO14347.1 - 0.47 10.1 3.4 1.6 8.4 0.4 2.3 2 0 0 2 2 2 0 Sec20 AAA_5 PF07728.9 KLO14347.1 - 0.62 9.7 3.9 0.87 9.3 2.7 1.3 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Occludin_ELL PF07303.8 KLO14347.1 - 2 9.1 9.6 1.1 9.9 0.7 2.5 1 1 1 2 2 2 0 Occludin homology domain DUF4239 PF14023.1 KLO14347.1 - 2.2 7.5 8.0 2.2 7.5 0.8 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF4239) V_ATPase_I PF01496.14 KLO14347.1 - 2.9 5.6 10.0 3.2 5.4 6.9 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF416 PF04222.7 KLO14347.1 - 3.4 6.7 13.3 1 8.4 0.9 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF416) DUF3708 PF12501.3 KLO14347.1 - 5.3 6.8 5.1 22 4.8 0.3 2.0 1 1 1 2 2 2 0 Phosphate ATP-binding cassette transporter TBPIP PF07106.8 KLO14347.1 - 8.4 5.9 12.7 2 7.9 5.8 1.9 1 1 2 3 3 3 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DUF1664 PF07889.7 KLO14347.1 - 9.5 6.0 8.4 15 5.4 0.2 2.8 1 1 1 3 3 3 0 Protein of unknown function (DUF1664) AMP-binding PF00501.23 KLO14348.1 - 5.9e-32 110.5 0.0 8.4e-32 110.0 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme MFS_1 PF07690.11 KLO14349.1 - 1e-40 139.5 69.2 1.3e-29 102.9 13.2 3.0 1 1 2 3 3 3 3 Major Facilitator Superfamily OATP PF03137.15 KLO14349.1 - 0.04 11.9 8.2 0.4 8.6 0.1 2.7 2 1 1 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family ESSS PF10183.4 KLO14349.1 - 0.23 11.8 3.8 2.2 8.7 0.0 3.9 4 1 1 5 5 5 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) S1FA PF04689.8 KLO14349.1 - 0.67 9.8 6.3 0.31 10.9 0.1 2.8 2 0 0 2 2 2 0 DNA binding protein S1FA DUF3176 PF11374.3 KLO14350.1 - 0.0087 15.9 5.5 0.62 9.9 0.7 3.0 2 0 0 2 2 2 2 Protein of unknown function (DUF3176) DUF307 PF03733.8 KLO14351.1 - 3.2 8.2 6.3 0.31 11.5 0.5 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF307) DUF3176 PF11374.3 KLO14354.1 - 0.081 12.7 5.5 0.46 10.3 3.8 2.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3176) Imm29 PF15575.1 KLO14354.1 - 0.12 11.9 0.2 0.24 11.0 0.1 1.4 1 0 0 1 1 1 0 Immunity protein 29 Metallophos PF00149.23 KLO14357.1 - 1.1e-10 41.2 0.2 2.4e-10 40.1 0.1 1.4 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 KLO14357.1 - 9.1e-08 32.0 0.0 1.6e-07 31.2 0.0 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain ABC2_membrane PF01061.19 KLO14358.1 - 4.1e-79 264.6 62.9 1.2e-41 142.2 16.8 3.4 4 0 0 4 4 4 2 ABC-2 type transporter ABC_tran PF00005.22 KLO14358.1 - 1.2e-36 126.0 0.0 2.2e-17 63.6 0.0 2.8 3 0 0 3 3 2 2 ABC transporter PDR_CDR PF06422.7 KLO14358.1 - 1.5e-32 111.3 0.8 3.8e-28 97.1 0.0 2.8 2 0 0 2 2 2 2 CDR ABC transporter ABC_trans_N PF14510.1 KLO14358.1 - 3.4e-15 55.8 0.1 7.4e-15 54.8 0.0 1.6 1 0 0 1 1 1 1 ABC-transporter extracellular N-terminal AAA_25 PF13481.1 KLO14358.1 - 2.6e-07 30.2 0.1 0.0037 16.6 0.0 2.8 3 0 0 3 3 3 2 AAA domain DUF258 PF03193.11 KLO14358.1 - 1.6e-06 27.3 0.0 2.4e-05 23.5 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_22 PF13401.1 KLO14358.1 - 4.2e-06 26.9 0.0 0.28 11.3 0.0 3.5 4 1 0 4 4 2 2 AAA domain AAA_33 PF13671.1 KLO14358.1 - 7e-06 25.9 0.0 0.025 14.4 0.0 2.6 2 0 0 2 2 2 2 AAA domain UPF0079 PF02367.12 KLO14358.1 - 0.00011 21.8 0.9 0.18 11.4 0.1 2.5 2 0 0 2 2 2 2 Uncharacterised P-loop hydrolase UPF0079 ABC2_membrane_3 PF12698.2 KLO14358.1 - 0.00012 21.1 55.0 0.001 18.2 21.2 3.5 2 1 0 2 2 2 1 ABC-2 family transporter protein cobW PF02492.14 KLO14358.1 - 0.00016 21.1 0.9 0.013 14.9 0.3 2.5 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_17 PF13207.1 KLO14358.1 - 0.00018 22.3 0.0 0.011 16.5 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 KLO14358.1 - 0.00032 20.7 0.6 0.069 13.1 0.2 2.8 2 1 0 2 2 2 1 AAA ATPase domain AAA_18 PF13238.1 KLO14358.1 - 0.00086 19.6 0.0 0.028 14.7 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 KLO14358.1 - 0.0018 17.9 0.3 0.25 11.1 0.0 2.6 2 0 0 2 2 2 1 Part of AAA domain NACHT PF05729.7 KLO14358.1 - 0.0022 17.6 0.1 0.67 9.5 0.0 2.7 2 0 0 2 2 2 1 NACHT domain AAA_28 PF13521.1 KLO14358.1 - 0.0025 17.8 0.1 0.041 13.8 0.1 2.5 2 0 0 2 2 2 1 AAA domain AAA_21 PF13304.1 KLO14358.1 - 0.0065 16.4 0.0 0.56 10.1 0.0 2.9 3 0 0 3 3 3 1 AAA domain AAA_29 PF13555.1 KLO14358.1 - 0.0071 15.8 0.7 0.056 12.9 0.2 2.3 2 0 0 2 2 2 1 P-loop containing region of AAA domain FtsK_SpoIIIE PF01580.13 KLO14358.1 - 0.0072 15.8 0.3 2.2 7.7 0.0 2.4 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA_30 PF13604.1 KLO14358.1 - 0.0096 15.5 0.1 1.4 8.4 0.1 2.3 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.7 KLO14358.1 - 0.014 14.4 0.0 1.3 8.0 0.0 2.5 2 0 0 2 2 2 0 Zeta toxin SMC_N PF02463.14 KLO14358.1 - 0.018 14.2 0.0 0.29 10.3 0.0 2.5 3 0 0 3 3 3 0 RecF/RecN/SMC N terminal domain AAA PF00004.24 KLO14358.1 - 0.023 14.8 0.0 6.2 7.0 0.0 2.7 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) SbcCD_C PF13558.1 KLO14358.1 - 0.029 14.2 0.0 4.4 7.2 0.0 2.7 2 0 0 2 2 2 0 Putative exonuclease SbcCD, C subunit MMR_HSR1 PF01926.18 KLO14358.1 - 0.05 13.5 0.1 1.6 8.7 0.1 2.7 2 0 0 2 2 2 0 50S ribosome-binding GTPase Miro PF08477.8 KLO14358.1 - 0.053 14.0 0.0 8.1 6.9 0.0 3.0 3 0 0 3 3 3 0 Miro-like protein PduV-EutP PF10662.4 KLO14358.1 - 0.079 12.4 0.2 1.7 8.1 0.1 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Septin PF00735.13 KLO14358.1 - 0.088 11.8 0.0 7.8 5.4 0.0 2.2 2 0 0 2 2 2 0 Septin AAA_10 PF12846.2 KLO14358.1 - 0.093 12.1 0.2 5.1 6.4 0.1 2.8 3 0 0 3 3 2 0 AAA-like domain DUF3176 PF11374.3 KLO14361.1 - 0.0066 16.3 2.4 0.018 14.9 0.1 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF3176) Abhydrolase_6 PF12697.2 KLO14363.1 - 7.2e-31 107.8 1.8 1.6e-30 106.6 1.3 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KLO14363.1 - 4.9e-18 65.5 0.0 3.2e-15 56.3 0.0 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KLO14363.1 - 6.4e-13 48.6 0.0 1.2e-10 41.2 0.0 2.2 2 0 0 2 2 2 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 KLO14363.1 - 1.5e-07 31.1 0.0 4.8e-07 29.5 0.0 1.9 2 0 0 2 2 2 1 Putative lysophospholipase Chlorophyllase2 PF12740.2 KLO14363.1 - 0.00052 18.9 0.0 0.00096 18.1 0.0 1.3 1 0 0 1 1 1 1 Chlorophyllase enzyme DLH PF01738.13 KLO14363.1 - 0.00099 18.4 0.0 0.0015 17.8 0.0 1.3 1 0 0 1 1 1 1 Dienelactone hydrolase family Chlorophyllase PF07224.6 KLO14363.1 - 0.0011 17.8 0.0 0.0016 17.2 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase Esterase PF00756.15 KLO14363.1 - 0.017 14.5 0.1 0.083 12.3 0.0 1.9 1 1 0 1 1 1 0 Putative esterase Peptidase_S9 PF00326.16 KLO14363.1 - 0.023 13.8 0.0 3 7.0 0.0 2.8 2 1 0 2 2 2 0 Prolyl oligopeptidase family Esterase_phd PF10503.4 KLO14363.1 - 0.12 11.6 0.4 0.26 10.5 0.3 1.5 1 0 0 1 1 1 0 Esterase PHB depolymerase Ndr PF03096.9 KLO14363.1 - 0.15 10.5 0.0 0.38 9.1 0.0 1.6 2 0 0 2 2 2 0 Ndr family EHN PF06441.7 KLO14363.1 - 0.18 11.7 0.3 0.47 10.4 0.1 1.8 2 0 0 2 2 2 0 Epoxide hydrolase N terminus Oxidored_FMN PF00724.15 KLO14364.1 - 2.7e-35 121.9 0.0 3.9e-35 121.4 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family DUF1774 PF08611.5 KLO14366.1 - 3.5 7.8 10.7 0.081 13.0 1.0 2.3 2 1 0 2 2 2 0 Fungal protein of unknown function (DUF1774) DIM PF08194.7 KLO14367.1 - 0.31 11.0 2.0 0.52 10.3 1.4 1.4 1 0 0 1 1 1 0 DIM protein Pkinase PF00069.20 KLO14368.1 - 7.7e-69 231.7 0.0 1.1e-68 231.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KLO14368.1 - 4.5e-35 120.9 0.0 9.2e-35 119.9 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 KLO14368.1 - 0.0028 17.4 0.0 0.0094 15.7 0.0 1.8 2 0 0 2 2 2 1 Phosphotransferase enzyme family F-box-like PF12937.2 KLO14369.1 - 0.0098 15.6 0.1 0.035 13.8 0.1 1.9 1 1 0 1 1 1 1 F-box-like F-box-like PF12937.2 KLO14370.1 - 0.0029 17.2 0.9 0.01 15.5 0.6 1.9 1 1 0 1 1 1 1 F-box-like zf-C3HC4_3 PF13920.1 KLO14371.1 - 6.2e-10 38.5 6.2 1.3e-08 34.3 1.3 2.3 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KLO14371.1 - 4.8e-06 26.4 4.8 7.3e-06 25.9 1.6 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KLO14371.1 - 0.00019 20.9 1.6 0.00071 19.1 0.4 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KLO14371.1 - 0.00021 21.0 3.9 0.0041 16.9 1.1 2.6 2 0 0 2 2 2 1 Ring finger domain zf-RING_5 PF14634.1 KLO14371.1 - 0.011 15.5 2.6 0.11 12.2 0.5 2.3 2 0 0 2 2 2 0 zinc-RING finger domain Prok-RING_4 PF14447.1 KLO14371.1 - 0.24 10.9 4.1 0.21 11.1 0.2 2.3 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 6PF2K PF01591.13 KLO14372.1 - 1.9e-62 210.2 0.0 2.6e-62 209.8 0.0 1.2 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.17 KLO14372.1 - 6.7e-24 84.7 0.0 3.2e-23 82.5 0.0 2.0 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.1 KLO14372.1 - 2.4e-07 30.7 0.0 4.1e-07 29.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain KTI12 PF08433.5 KLO14372.1 - 1.1e-05 24.8 0.1 2e-05 23.9 0.1 1.4 1 1 0 1 1 1 1 Chromatin associated protein KTI12 Zeta_toxin PF06414.7 KLO14372.1 - 0.0017 17.5 0.0 0.0031 16.6 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin AAA_17 PF13207.1 KLO14372.1 - 0.0019 19.0 0.2 0.0065 17.2 0.1 2.1 1 1 0 1 1 1 1 AAA domain tRNA_lig_kinase PF08303.6 KLO14372.1 - 0.074 12.9 0.0 0.42 10.4 0.0 2.0 2 0 0 2 2 2 0 tRNA ligase kinase domain APS_kinase PF01583.15 KLO14372.1 - 0.19 11.3 0.1 0.37 10.4 0.0 1.3 1 0 0 1 1 1 0 Adenylylsulphate kinase MMR_HSR1 PF01926.18 KLO14375.1 - 2.1e-10 40.5 0.0 5.2e-10 39.2 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 KLO14375.1 - 0.0017 17.6 0.1 0.01 15.0 0.1 2.0 2 0 0 2 2 2 1 Ferrous iron transport protein B MCM PF00493.18 KLO14375.1 - 0.0022 16.8 0.0 0.01 14.6 0.0 1.9 2 0 0 2 2 2 1 MCM2/3/5 family AAA_29 PF13555.1 KLO14375.1 - 0.015 14.8 0.0 0.03 13.8 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain IIGP PF05049.8 KLO14375.1 - 0.018 13.8 0.0 0.029 13.2 0.0 1.2 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) AAA_17 PF13207.1 KLO14375.1 - 0.021 15.6 0.0 0.073 13.8 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 KLO14375.1 - 0.032 14.5 0.4 0.09 13.0 0.0 2.0 2 0 0 2 2 2 0 AAA domain GTP_EFTU PF00009.22 KLO14375.1 - 0.037 13.4 0.0 3.5 7.0 0.0 2.7 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain AAA_16 PF13191.1 KLO14375.1 - 0.045 13.7 0.0 0.15 12.0 0.0 1.9 1 0 0 1 1 1 0 AAA ATPase domain FtsK_SpoIIIE PF01580.13 KLO14375.1 - 0.048 13.1 0.1 0.24 10.8 0.0 1.9 2 0 0 2 2 2 0 FtsK/SpoIIIE family Arf PF00025.16 KLO14375.1 - 0.051 12.8 0.0 0.18 11.0 0.0 1.8 2 0 0 2 2 2 0 ADP-ribosylation factor family DUF258 PF03193.11 KLO14375.1 - 0.06 12.5 0.0 0.1 11.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 Dynamin_N PF00350.18 KLO14375.1 - 0.088 12.6 0.9 0.3 10.9 0.0 2.1 2 0 0 2 2 2 0 Dynamin family IstB_IS21 PF01695.12 KLO14375.1 - 0.095 12.1 0.0 0.18 11.2 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein G-alpha PF00503.15 KLO14375.1 - 0.12 11.0 0.2 1.6 7.2 0.0 2.0 2 0 0 2 2 2 0 G-protein alpha subunit Peptidase_S10 PF00450.17 KLO14376.1 - 2.2e-107 359.7 0.1 2.9e-107 359.4 0.0 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase Abhydrolase_6 PF12697.2 KLO14376.1 - 0.016 15.0 0.0 0.22 11.3 0.0 2.2 1 1 0 1 1 1 0 Alpha/beta hydrolase family FA_desaturase PF00487.19 KLO14377.1 - 2e-23 83.1 27.4 4.5e-23 82.0 19.0 1.6 1 1 0 1 1 1 1 Fatty acid desaturase DUF3474 PF11960.3 KLO14377.1 - 0.0043 17.0 0.0 0.0078 16.2 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3474) PAM2 PF07145.10 KLO14377.1 - 0.1 12.1 1.4 4.8 6.9 0.1 2.5 2 0 0 2 2 2 0 Ataxin-2 C-terminal region FA_desaturase PF00487.19 KLO14378.1 - 2e-23 83.1 26.6 3.6e-23 82.3 18.4 1.4 1 0 0 1 1 1 1 Fatty acid desaturase DUF3474 PF11960.3 KLO14378.1 - 0.0011 18.9 0.0 0.0019 18.2 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3474) L6_membrane PF05805.7 KLO14378.1 - 0.089 12.3 0.1 6.5 6.2 0.1 2.2 2 0 0 2 2 2 0 L6 membrane protein Sec2p PF06428.6 KLO14382.1 - 3.3e-13 49.3 8.4 3.3e-13 49.3 5.8 2.0 2 0 0 2 2 2 1 GDP/GTP exchange factor Sec2p CsbD PF05532.7 KLO14383.1 - 0.00016 21.2 2.4 0.0023 17.5 0.7 2.6 2 1 0 2 2 2 2 CsbD-like CsbD PF05532.7 KLO14384.1 - 1.3e-05 24.7 1.0 4e-05 23.2 0.7 1.8 1 0 0 1 1 1 1 CsbD-like CsbD PF05532.7 KLO14385.1 - 0.00049 19.7 3.1 0.0017 17.9 2.2 1.9 1 0 0 1 1 1 1 CsbD-like TPR_10 PF13374.1 KLO14385.1 - 0.37 10.7 4.7 0.74 9.8 3.2 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat MFS_1 PF07690.11 KLO14386.1 - 1.2e-18 67.0 37.7 1.2e-18 67.0 26.1 1.3 1 1 0 1 1 1 1 Major Facilitator Superfamily OEP PF02321.13 KLO14386.1 - 0.12 11.9 0.0 0.17 11.4 0.0 1.2 1 0 0 1 1 1 0 Outer membrane efflux protein DFP PF04127.10 KLO14388.1 - 3.3e-20 72.4 0.0 5.2e-12 45.7 0.0 2.3 2 0 0 2 2 2 2 DNA / pantothenate metabolism flavoprotein DUF3551 PF12071.3 KLO14390.1 - 0.077 12.5 0.1 0.1 12.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3551) Oxidored_FMN PF00724.15 KLO14392.1 - 1.3e-34 119.6 0.0 1.8e-34 119.2 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Aldo_ket_red PF00248.16 KLO14393.1 - 4e-52 176.7 0.0 4.8e-52 176.5 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family PX PF00787.19 KLO14394.1 - 1.3e-19 70.0 0.0 3.7e-19 68.5 0.0 1.9 1 0 0 1 1 1 1 PX domain BAR_3_WASP_bdg PF10456.4 KLO14394.1 - 8.7e-11 41.5 0.4 6.5e-09 35.4 0.2 2.4 2 0 0 2 2 2 1 WASP-binding domain of Sorting nexin protein SH3_1 PF00018.23 KLO14394.1 - 1.9e-06 27.1 0.9 7.3e-06 25.2 0.1 2.4 2 1 0 2 2 2 1 SH3 domain SH3_2 PF07653.12 KLO14394.1 - 6.4e-06 25.5 0.0 1.4e-05 24.4 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.1 KLO14394.1 - 0.00036 20.0 0.0 0.00084 18.8 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain DUF3824 PF12868.2 KLO14395.1 - 0.07 14.0 0.1 0.088 13.7 0.1 1.1 1 0 0 1 1 1 0 Domain of unknwon function (DUF3824) WD40 PF00400.27 KLO14398.1 - 9.1e-53 174.3 19.5 7.2e-14 51.0 0.1 12.4 13 0 0 13 13 13 7 WD domain, G-beta repeat Utp12 PF04003.7 KLO14398.1 - 1.9e-17 63.1 0.0 3e-17 62.4 0.0 1.4 1 0 0 1 1 1 1 Dip2/Utp12 Family eIF2A PF08662.6 KLO14398.1 - 2.1e-07 30.8 1.3 0.13 11.9 0.0 4.7 2 2 0 3 3 3 2 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 KLO14398.1 - 0.00015 20.0 0.9 0.037 12.1 0.1 2.8 1 1 1 3 3 3 2 Nucleoporin Nup120/160 IKI3 PF04762.7 KLO14398.1 - 0.00025 19.0 0.0 0.97 7.1 0.0 3.5 3 1 1 4 4 4 2 IKI3 family Coatomer_WDAD PF04053.9 KLO14398.1 - 0.0015 17.4 0.0 0.3 9.8 0.0 3.1 2 1 0 3 3 3 1 Coatomer WD associated region Nucleoporin_N PF08801.6 KLO14398.1 - 0.0015 17.3 1.2 5.9 5.5 0.0 4.3 1 1 3 5 5 5 1 Nup133 N terminal like Cytochrom_D1 PF02239.11 KLO14398.1 - 0.051 11.8 0.3 14 3.8 0.0 3.4 3 1 1 4 4 4 0 Cytochrome D1 heme domain DPPIV_N PF00930.16 KLO14398.1 - 0.06 11.9 0.3 0.28 9.7 0.1 2.3 3 1 0 3 3 3 0 Dipeptidyl peptidase IV (DPP IV) N-terminal region DUF1513 PF07433.6 KLO14398.1 - 0.11 11.3 0.0 41 2.9 0.0 3.6 3 0 0 3 3 3 0 Protein of unknown function (DUF1513) DUF2840 PF11000.3 KLO14399.1 - 0.099 12.1 0.0 0.1 12.1 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2840) F-box-like PF12937.2 KLO14400.1 - 9.5e-08 31.6 0.1 2.9e-07 30.1 0.1 1.9 1 0 0 1 1 1 1 F-box-like Omega-toxin PF06357.6 KLO14401.1 - 0.45 10.1 3.7 0.78 9.3 2.5 1.4 1 0 0 1 1 1 0 Omega-atracotoxin FAD_binding_3 PF01494.14 KLO14402.1 - 9e-21 74.3 0.0 1.8e-09 37.1 0.0 2.3 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.1 KLO14402.1 - 0.00099 19.0 0.0 0.0022 17.9 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain SE PF08491.5 KLO14402.1 - 0.0073 15.1 0.0 0.11 11.3 0.0 2.2 2 0 0 2 2 2 1 Squalene epoxidase NAD_binding_9 PF13454.1 KLO14402.1 - 0.013 15.2 0.0 0.024 14.4 0.0 1.4 1 0 0 1 1 1 0 FAD-NAD(P)-binding Pyr_redox_3 PF13738.1 KLO14402.1 - 0.067 13.2 0.1 0.31 11.0 0.1 2.0 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase RRM_1 PF00076.17 KLO14403.1 - 1.1e-11 44.1 0.1 1.6e-05 24.4 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KLO14403.1 - 7e-10 38.7 0.1 1.1e-07 31.6 0.1 2.3 1 1 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) FoP_duplication PF13865.1 KLO14403.1 - 6.9e-07 29.6 0.6 1.4e-06 28.6 0.4 1.5 1 0 0 1 1 1 1 C-terminal duplication domain of Friend of PRMT1 RRM_5 PF13893.1 KLO14403.1 - 4.4e-06 26.4 0.0 1.3e-05 24.9 0.0 1.9 3 0 0 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF385 PF04075.9 KLO14403.1 - 0.093 12.6 0.1 0.19 11.6 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF385) ATG11 PF10377.4 KLO14405.1 - 3.1e-32 111.1 3.0 4e-32 110.8 0.1 2.4 2 0 0 2 2 2 1 Autophagy-related protein 11 Sugar_tr PF00083.19 KLO14406.1 - 7.6e-84 281.8 24.6 8.6e-84 281.6 17.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KLO14406.1 - 3.9e-26 91.5 29.2 3.9e-26 91.5 20.2 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 KLO14406.1 - 1.3e-06 27.1 25.7 0.00011 20.7 0.4 3.2 2 1 0 3 3 3 2 MFS/sugar transport protein Gate PF07670.9 KLO14406.1 - 0.89 9.4 8.1 0.27 11.1 2.6 2.4 2 1 0 2 2 2 0 Nucleoside recognition F-box-like PF12937.2 KLO14407.1 - 4.9e-07 29.3 0.2 1.5e-06 27.8 0.2 1.8 1 0 0 1 1 1 1 F-box-like PIG-L PF02585.12 KLO14407.1 - 0.041 14.4 0.1 0.09 13.2 0.1 1.6 1 0 0 1 1 1 0 GlcNAc-PI de-N-acetylase Capsid_NCLDV PF04451.7 KLO14407.1 - 0.043 12.8 0.3 1.8 7.4 0.1 2.8 3 0 0 3 3 3 0 Large eukaryotic DNA virus major capsid protein Sdh5 PF03937.11 KLO14408.1 - 1.1e-26 92.2 0.5 1.5e-26 91.8 0.4 1.2 1 0 0 1 1 1 1 Flavinator of succinate dehydrogenase Gly_transf_sug PF04488.10 KLO14409.1 - 1e-05 25.8 0.0 2e-05 24.9 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Caps_synth PF05704.7 KLO14409.1 - 0.068 12.3 0.8 0.13 11.4 0.5 1.4 1 0 0 1 1 1 0 Capsular polysaccharide synthesis protein Ribosomal_S6e PF01092.14 KLO14410.1 - 1.9e-57 192.3 0.1 3.3e-57 191.6 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein S6e Ribosomal_S13_N PF08069.7 KLO14411.1 - 1.4e-30 104.9 0.1 2.3e-30 104.2 0.1 1.4 1 0 0 1 1 1 1 Ribosomal S13/S15 N-terminal domain Ribosomal_S15 PF00312.17 KLO14411.1 - 3.7e-18 65.0 0.1 5.1e-18 64.6 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein S15 PAX PF00292.13 KLO14411.1 - 0.051 13.2 0.0 0.091 12.4 0.0 1.4 1 0 0 1 1 1 0 'Paired box' domain HTH_32 PF13565.1 KLO14411.1 - 0.086 13.6 0.3 0.16 12.7 0.0 1.7 2 1 0 2 2 2 0 Homeodomain-like domain SMC_N PF02463.14 KLO14413.1 - 2.3e-52 177.3 36.6 6e-52 176.0 25.4 1.8 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 KLO14413.1 - 1.1e-31 109.3 1.9 4e-31 107.4 0.0 3.0 3 0 0 3 3 3 1 SMC proteins Flexible Hinge Domain AAA_23 PF13476.1 KLO14413.1 - 2.3e-13 50.9 11.0 2.3e-13 50.9 7.6 6.6 2 2 1 3 3 1 1 AAA domain AAA_21 PF13304.1 KLO14413.1 - 1.4e-10 41.5 13.4 8.8e-07 29.1 1.3 4.0 4 1 0 4 4 4 2 AAA domain AAA_29 PF13555.1 KLO14413.1 - 4.5e-07 29.2 0.0 9.3e-07 28.2 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain WEMBL PF05701.6 KLO14413.1 - 8.4e-05 21.2 2.1 8.4e-05 21.2 1.4 4.7 3 2 2 5 5 4 1 Weak chloroplast movement under blue light Reo_sigmaC PF04582.7 KLO14413.1 - 0.00013 21.2 34.7 0.0017 17.6 2.9 5.7 4 1 2 6 6 6 2 Reovirus sigma C capsid protein AAA_13 PF13166.1 KLO14413.1 - 0.00016 20.3 99.3 0.0025 16.3 13.8 6.3 4 3 2 6 6 6 4 AAA domain SbcCD_C PF13558.1 KLO14413.1 - 0.00078 19.3 0.0 0.0039 17.0 0.0 2.3 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit Laminin_II PF06009.7 KLO14413.1 - 0.0037 17.0 6.7 0.0037 17.0 4.7 8.3 4 2 3 8 8 8 2 Laminin Domain II Spc7 PF08317.6 KLO14413.1 - 0.0042 15.7 102.5 0.14 10.8 12.8 6.4 3 2 4 7 7 7 5 Spc7 kinetochore protein ABC_tran PF00005.22 KLO14413.1 - 0.024 14.9 0.0 0.024 14.9 0.0 6.0 5 1 0 5 5 4 0 ABC transporter DUF3584 PF12128.3 KLO14413.1 - 0.14 9.4 94.5 0.0046 14.3 27.9 5.0 5 1 1 6 6 6 0 Protein of unknown function (DUF3584) Phycobilisome PF00502.14 KLO14413.1 - 0.32 10.7 11.5 0.077 12.7 0.2 4.0 3 1 1 4 4 4 0 Phycobilisome protein MtrB PF05440.7 KLO14413.1 - 1.8 8.6 3.5 2.2 8.3 0.4 2.7 2 1 0 2 2 2 0 Tetrahydromethanopterin S-methyltransferase subunit B DUF3650 PF12368.3 KLO14414.1 - 0.01 15.2 0.3 0.018 14.5 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3650) DUF4600 PF15372.1 KLO14414.1 - 0.32 11.1 2.9 0.5 10.5 1.8 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4600) Peptidase_S41 PF03572.13 KLO14415.1 - 9.7e-06 25.0 0.0 2.1e-05 24.0 0.0 1.5 1 0 0 1 1 1 1 Peptidase family S41 ADH_N PF08240.7 KLO14417.1 - 1.8e-29 101.6 0.6 5.4e-29 100.1 0.2 1.9 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KLO14417.1 - 2e-22 79.0 0.0 3.7e-22 78.2 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 KLO14417.1 - 5.7e-06 27.2 0.0 1.4e-05 25.9 0.0 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Methyltransf_18 PF12847.2 KLO14417.1 - 0.0046 17.5 0.0 0.0091 16.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain AlaDh_PNT_C PF01262.16 KLO14417.1 - 0.0083 15.7 0.0 0.017 14.6 0.0 1.5 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.14 KLO14417.1 - 0.011 14.8 0.0 0.025 13.7 0.0 1.5 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Methyltransf_11 PF08241.7 KLO14417.1 - 0.029 14.8 0.0 0.092 13.2 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase domain MTS PF05175.9 KLO14417.1 - 0.091 12.1 0.0 0.15 11.4 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain YdfZ PF14001.1 KLO14417.1 - 0.14 12.4 0.2 2.5 8.4 0.0 2.6 2 0 0 2 2 2 0 YdfZ protein UDPG_MGDP_dh_N PF03721.9 KLO14417.1 - 0.15 11.4 0.0 0.26 10.6 0.0 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain p450 PF00067.17 KLO14423.1 - 6.6e-81 272.1 0.0 1.8e-80 270.7 0.0 1.6 1 1 0 1 1 1 1 Cytochrome P450 zf-C2H2_4 PF13894.1 KLO14426.1 - 0.022 15.0 1.1 0.14 12.5 0.8 2.5 1 0 0 1 1 1 0 C2H2-type zinc finger A-2_8-polyST PF07388.6 KLO14426.1 - 0.031 12.6 0.0 0.046 12.0 0.0 1.1 1 0 0 1 1 1 0 Alpha-2,8-polysialyltransferase (POLYST) zf-C2H2 PF00096.21 KLO14426.1 - 0.18 12.1 7.1 0.12 12.7 1.5 2.8 2 0 0 2 2 2 0 Zinc finger, C2H2 type PIN_3 PF13470.1 KLO14427.1 - 0.39 11.3 15.9 3.6 8.2 1.2 4.1 3 1 0 4 4 4 0 PIN domain DUF572 PF04502.8 KLO14427.1 - 2.1 7.4 37.4 1.3 8.1 9.6 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF572) LSM PF01423.17 KLO14428.1 - 5.7e-17 61.0 0.1 7.4e-17 60.6 0.1 1.1 1 0 0 1 1 1 1 LSM domain PHD PF00628.24 KLO14429.1 - 1.1e-09 37.8 8.2 1.1e-09 37.8 5.7 1.9 2 0 0 2 2 2 1 PHD-finger zf-CpG_bind_C PF12269.3 KLO14429.1 - 0.98 8.8 10.2 0.98 8.8 1.7 2.5 2 0 0 2 2 2 0 CpG binding protein zinc finger C terminal domain DLH PF01738.13 KLO14430.1 - 5.4e-21 74.8 0.0 7.1e-21 74.4 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family DUF2305 PF10230.4 KLO14430.1 - 0.0004 19.8 0.0 0.00051 19.5 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2305) Chlorophyllase2 PF12740.2 KLO14430.1 - 0.14 11.0 0.1 0.22 10.3 0.0 1.4 1 1 0 1 1 1 0 Chlorophyllase enzyme Chlorophyllase PF07224.6 KLO14430.1 - 0.14 10.8 0.2 0.23 10.2 0.1 1.2 1 0 0 1 1 1 0 Chlorophyllase GTP_EFTU PF00009.22 KLO14431.1 - 1.3e-57 194.3 0.0 1.8e-57 193.7 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 KLO14431.1 - 3.1e-38 129.9 0.6 8.5e-38 128.5 0.1 2.0 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 KLO14431.1 - 2.3e-16 59.6 1.4 2.3e-16 59.6 1.0 2.1 2 0 0 2 2 2 1 Elongation factor Tu domain 2 GTP_EFTU_D4 PF14578.1 KLO14431.1 - 0.00046 19.7 0.3 0.00046 19.7 0.2 2.2 2 0 0 2 2 2 1 Elongation factor Tu domain 4 MMR_HSR1 PF01926.18 KLO14431.1 - 0.0019 18.1 0.2 0.0065 16.4 0.2 2.0 1 1 0 1 1 1 1 50S ribosome-binding GTPase 5HT_transporter PF03491.8 KLO14431.1 - 0.028 14.5 0.3 0.09 12.8 0.0 1.9 2 0 0 2 2 2 0 Serotonin (5-HT) neurotransmitter transporter, N-terminus Semialdhyde_dhC PF02774.13 KLO14431.1 - 0.065 13.0 0.3 0.23 11.2 0.1 1.9 1 1 1 2 2 2 0 Semialdehyde dehydrogenase, dimerisation domain Pkinase PF00069.20 KLO14432.1 - 1e-38 132.9 0.0 1.6e-37 129.0 0.0 2.1 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 KLO14432.1 - 2e-11 43.5 0.0 4.8e-10 38.9 0.0 2.8 3 1 0 3 3 3 1 Protein tyrosine kinase Kinase-like PF14531.1 KLO14432.1 - 0.32 9.8 0.0 0.52 9.2 0.0 1.2 1 0 0 1 1 1 0 Kinase-like Ribosomal_L32e PF01655.13 KLO14433.1 - 3.8e-48 162.0 3.0 4.5e-48 161.8 2.1 1.0 1 0 0 1 1 1 1 Ribosomal protein L32 CAAP1 PF15335.1 KLO14433.1 - 0.056 13.6 0.2 0.092 12.9 0.2 1.3 1 0 0 1 1 1 0 Caspase activity and apoptosis inhibitor 1 Memo PF01875.12 KLO14434.1 - 7.6e-73 244.7 0.0 8.9e-73 244.5 0.0 1.0 1 0 0 1 1 1 1 Memo-like protein Cellulase PF00150.13 KLO14435.1 - 1.2e-11 44.4 0.5 1.8e-11 43.7 0.4 1.3 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_cc PF11790.3 KLO14435.1 - 0.0081 15.6 0.2 0.037 13.4 0.0 2.0 2 0 0 2 2 2 1 Glycosyl hydrolase catalytic core Acetyltransf_8 PF13523.1 KLO14436.1 - 0.00048 20.0 0.0 0.00071 19.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 KLO14436.1 - 0.019 15.0 0.0 0.29 11.2 0.0 2.5 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain DUF547 PF04784.9 KLO14436.1 - 0.047 13.5 0.0 0.071 12.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF547 Abhydrolase_6 PF12697.2 KLO14437.1 - 2.3e-26 93.1 0.0 3.9e-26 92.3 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KLO14437.1 - 7.7e-18 64.6 0.0 9.7e-18 64.3 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KLO14437.1 - 1.4e-14 54.2 0.3 3.8e-10 39.7 0.1 2.1 1 1 0 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.3 KLO14437.1 - 9e-07 28.6 0.0 2.3e-05 24.1 0.0 2.4 2 0 0 2 2 2 1 Putative lysophospholipase DLH PF01738.13 KLO14437.1 - 2.6e-06 26.8 1.0 0.0014 17.9 0.2 3.0 2 1 0 2 2 2 1 Dienelactone hydrolase family FSH1 PF03959.8 KLO14437.1 - 0.003 17.0 0.0 0.0056 16.1 0.0 1.4 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Lipase_2 PF01674.13 KLO14437.1 - 0.0031 16.8 0.1 0.0052 16.1 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 2) Peptidase_S9 PF00326.16 KLO14437.1 - 0.0041 16.3 0.0 0.021 14.0 0.0 1.9 1 1 0 1 1 1 1 Prolyl oligopeptidase family BAAT_C PF08840.6 KLO14437.1 - 0.015 14.9 0.0 0.024 14.3 0.0 1.2 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_2 PF02230.11 KLO14437.1 - 0.048 13.1 0.1 4.5 6.6 0.0 2.3 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase RMMBL PF07521.7 KLO14437.1 - 0.06 13.1 0.2 2.4 8.0 0.0 2.4 2 0 0 2 2 2 0 RNA-metabolising metallo-beta-lactamase Elong_Iki1 PF10483.4 KLO14438.1 - 1.9e-16 60.2 0.1 5e-16 58.8 0.1 1.6 1 1 0 1 1 1 1 Elongator subunit Iki1 KH_1 PF00013.24 KLO14439.1 - 4.9e-41 138.2 11.7 1.1e-16 60.1 0.2 3.1 3 0 0 3 3 3 3 KH domain KH_3 PF13014.1 KLO14439.1 - 1.2e-28 98.2 17.5 8.9e-10 38.0 1.6 3.4 3 0 0 3 3 3 3 KH domain KH_2 PF07650.12 KLO14439.1 - 2.1e-10 39.9 7.7 0.0041 16.6 0.4 3.5 3 0 0 3 3 3 3 KH domain KH_4 PF13083.1 KLO14439.1 - 3.8e-10 39.2 1.6 0.009 15.6 0.0 3.4 3 0 0 3 3 3 3 KH domain KH_5 PF13184.1 KLO14439.1 - 6.4e-05 22.6 7.7 0.076 12.8 0.1 3.8 4 0 0 4 4 4 3 NusA-like KH domain dUTPase PF00692.14 KLO14439.1 - 0.014 14.8 1.0 0.37 10.2 0.1 2.6 2 1 0 2 2 2 0 dUTPase MARVEL PF01284.18 KLO14440.1 - 5.5e-05 23.0 3.5 7.8e-05 22.5 2.4 1.2 1 0 0 1 1 1 1 Membrane-associating domain MFS_1 PF07690.11 KLO14441.1 - 3.4e-22 78.6 23.4 3.4e-22 78.6 16.2 2.3 3 0 0 3 3 3 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KLO14441.1 - 0.00031 19.4 15.1 0.0052 15.4 10.7 2.8 1 1 0 1 1 1 1 Sugar (and other) transporter RGCC PF15151.1 KLO14442.1 - 0.019 15.3 0.8 0.03 14.7 0.6 1.3 1 0 0 1 1 1 0 Response gene to complement 32 protein family HEAT PF02985.17 KLO14443.1 - 4.1e-44 144.7 17.0 0.00061 19.6 0.0 12.4 12 0 0 12 12 12 11 HEAT repeat HEAT_2 PF13646.1 KLO14443.1 - 4.6e-36 122.9 7.3 1.5e-08 34.7 0.0 7.4 2 2 4 7 7 7 7 HEAT repeats HEAT_EZ PF13513.1 KLO14443.1 - 4.7e-15 55.5 15.4 0.0014 19.0 0.2 9.5 6 4 4 10 10 10 4 HEAT-like repeat Vac14_Fab1_bd PF12755.2 KLO14443.1 - 5.4e-10 39.5 2.0 0.021 15.1 0.0 6.6 4 2 4 9 9 9 2 Vacuolar 14 Fab1-binding region Adaptin_N PF01602.15 KLO14443.1 - 2.8e-07 29.2 1.9 0.00084 17.7 0.2 3.3 1 1 2 3 3 3 2 Adaptin N terminal region Arm PF00514.18 KLO14443.1 - 1.3e-06 27.9 1.0 3.7 7.5 0.0 6.5 7 0 0 7 7 7 2 Armadillo/beta-catenin-like repeat HEAT_PBS PF03130.11 KLO14443.1 - 0.0012 19.1 2.7 0.55 10.8 0.0 4.4 4 0 0 4 4 4 1 PBS lyase HEAT-like repeat Cohesin_HEAT PF12765.2 KLO14443.1 - 0.0063 16.4 1.7 8.2 6.5 0.1 4.4 5 0 0 5 5 5 1 HEAT repeat associated with sister chromatid cohesion VASP_tetra PF08776.6 KLO14443.1 - 0.061 12.6 0.2 0.26 10.6 0.2 2.1 1 0 0 1 1 1 0 VASP tetramerisation domain DUF1877 PF08974.5 KLO14443.1 - 0.13 11.9 0.1 1.3 8.6 0.0 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF1877) TMEM154 PF15102.1 KLO14444.1 - 0.00033 20.3 0.3 0.00033 20.3 0.2 1.7 2 0 0 2 2 2 1 TMEM154 protein family DUF3377 PF11857.3 KLO14444.1 - 0.027 14.1 0.1 0.064 12.8 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3377) DNA_pol_A_exo1 PF01612.15 KLO14445.1 - 1.2e-09 37.9 0.4 3.2e-05 23.5 0.0 2.3 2 0 0 2 2 2 2 3'-5' exonuclease PHD PF00628.24 KLO14445.1 - 0.074 12.7 0.6 0.21 11.3 0.4 1.7 1 0 0 1 1 1 0 PHD-finger Glyco_transf_41 PF13844.1 KLO14446.1 - 1.7e-92 309.8 1.0 4.3e-43 146.9 0.0 3.2 3 0 0 3 3 3 3 Glycosyl transferase family 41 TPR_1 PF00515.23 KLO14446.1 - 7.3e-14 50.6 0.0 0.00065 19.2 0.0 4.8 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_11 PF13414.1 KLO14446.1 - 1.1e-13 50.5 0.0 3.7e-08 32.9 0.0 4.0 2 2 3 5 5 5 4 TPR repeat TPR_12 PF13424.1 KLO14446.1 - 7.2e-13 48.2 0.0 6.7e-07 29.1 0.0 3.5 2 2 2 4 4 4 4 Tetratricopeptide repeat TPR_2 PF07719.12 KLO14446.1 - 9.2e-09 34.5 0.0 0.21 11.5 0.0 4.6 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_17 PF13431.1 KLO14446.1 - 1.1e-08 34.5 0.0 0.19 12.0 0.0 5.2 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_8 PF13181.1 KLO14446.1 - 2.4e-08 33.1 0.0 0.071 12.9 0.0 4.6 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_7 PF13176.1 KLO14446.1 - 9.3e-08 31.3 0.0 0.15 11.9 0.0 3.9 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.1 KLO14446.1 - 2.7e-07 30.6 0.1 0.049 14.2 0.0 4.7 4 1 1 5 5 4 2 Tetratricopeptide repeat TPR_16 PF13432.1 KLO14446.1 - 2e-06 28.3 0.0 0.0027 18.3 0.0 3.1 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_10 PF13374.1 KLO14446.1 - 3.1e-06 26.9 0.1 0.17 11.8 0.0 5.3 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_19 PF14559.1 KLO14446.1 - 0.00013 22.2 0.0 0.057 13.7 0.0 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_6 PF13174.1 KLO14446.1 - 0.11 12.9 0.0 58 4.4 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat AGTRAP PF06396.6 KLO14447.1 - 0.012 15.3 0.4 0.021 14.5 0.3 1.4 1 0 0 1 1 1 0 Angiotensin II, type I receptor-associated protein (AGTRAP) WD40 PF00400.27 KLO14448.1 - 0.00011 21.9 16.2 0.088 12.7 0.0 5.5 6 0 0 6 6 6 3 WD domain, G-beta repeat IKI3 PF04762.7 KLO14448.1 - 0.13 10.1 0.1 3.7 5.2 0.0 2.0 2 0 0 2 2 2 0 IKI3 family Pex24p PF06398.6 KLO14450.1 - 4.8e-08 32.1 3.2 6.3e-08 31.8 2.2 1.2 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin HSCB_C PF07743.8 KLO14451.1 - 3e-14 53.2 2.4 3e-14 53.2 1.7 1.6 2 0 0 2 2 2 1 HSCB C-terminal oligomerisation domain DnaJ PF00226.26 KLO14451.1 - 7.7e-10 38.3 0.0 1.8e-09 37.2 0.0 1.6 2 0 0 2 2 2 1 DnaJ domain DZR PF12773.2 KLO14451.1 - 0.0037 17.0 0.9 0.0069 16.1 0.6 1.4 1 0 0 1 1 1 1 Double zinc ribbon zf-ribbon_3 PF13248.1 KLO14451.1 - 0.016 14.4 2.6 0.025 13.7 1.8 1.4 1 0 0 1 1 1 0 zinc-ribbon domain UPF0547 PF10571.4 KLO14451.1 - 0.058 13.0 5.5 0.41 10.3 3.7 2.1 1 1 1 2 2 2 0 Uncharacterised protein family UPF0547 DUF35_N PF12172.3 KLO14451.1 - 0.24 11.3 4.3 0.49 10.3 3.0 1.5 1 0 0 1 1 1 0 Rubredoxin-like zinc ribbon domain (DUF35_N) HA2 PF04408.18 KLO14452.1 - 1.6e-17 63.3 0.2 3.9e-17 62.1 0.1 1.6 1 0 0 1 1 1 1 Helicase associated domain (HA2) dsrm PF00035.20 KLO14452.1 - 7.8e-12 45.5 0.0 2.2e-05 24.9 0.0 2.6 2 0 0 2 2 2 2 Double-stranded RNA binding motif Helicase_C PF00271.26 KLO14452.1 - 8.8e-12 44.7 0.0 2.4e-11 43.3 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 KLO14452.1 - 7.6e-09 35.2 0.1 1.7e-08 34.1 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase OB_NTP_bind PF07717.11 KLO14452.1 - 3.2e-06 26.9 0.0 7.3e-06 25.7 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold ResIII PF04851.10 KLO14452.1 - 0.007 16.2 0.0 0.17 11.7 0.0 2.8 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_22 PF13401.1 KLO14452.1 - 0.011 15.8 0.1 0.06 13.4 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.1 KLO14452.1 - 0.017 14.8 0.0 0.067 12.9 0.0 2.1 1 0 0 1 1 1 0 Part of AAA domain DUF1833 PF08875.6 KLO14452.1 - 0.074 12.2 0.1 0.22 10.6 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1833) UvrD-helicase PF00580.16 KLO14452.1 - 0.1 11.8 0.0 0.2 10.8 0.0 1.5 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain Adaptin_N PF01602.15 KLO14453.1 - 2.4e-125 418.8 6.4 1.2e-124 416.5 5.6 1.3 2 0 0 2 2 2 1 Adaptin N terminal region Alpha_adaptin_C PF02296.11 KLO14453.1 - 7.1e-36 122.6 0.0 1.6e-35 121.4 0.0 1.6 1 0 0 1 1 1 1 Alpha adaptin AP2, C-terminal domain Alpha_adaptinC2 PF02883.15 KLO14453.1 - 4.2e-18 65.7 0.1 8.2e-18 64.7 0.0 1.5 1 0 0 1 1 1 1 Adaptin C-terminal domain RasGAP PF00616.14 KLO14454.1 - 1.6e-38 132.3 0.0 4.4e-38 130.9 0.0 1.7 2 0 0 2 2 2 1 GTPase-activator protein for Ras-like GTPase C2 PF00168.25 KLO14454.1 - 0.00022 21.0 0.0 0.0005 19.8 0.0 1.6 1 0 0 1 1 1 1 C2 domain ELO PF01151.13 KLO14455.1 - 1.2e-62 211.5 20.5 1.4e-62 211.2 14.2 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family NOD PF06816.8 KLO14456.1 - 0.081 12.0 0.4 0.14 11.2 0.3 1.4 1 0 0 1 1 1 0 NOTCH protein DUF1162 PF06650.7 KLO14457.1 - 2.7e-64 217.0 0.0 4.1e-61 206.6 0.0 2.9 2 0 0 2 2 2 2 Protein of unknown function (DUF1162) Chorein_N PF12624.2 KLO14457.1 - 2.8e-33 113.9 0.0 8.3e-33 112.4 0.0 1.8 1 0 0 1 1 1 1 N-terminal region of Chorein, a TM vesicle-mediated sorter ATG_C PF09333.6 KLO14457.1 - 4.5e-06 26.7 0.1 1.3e-05 25.2 0.0 1.7 1 0 0 1 1 1 1 ATG C terminal domain DUF1218 PF06749.7 KLO14457.1 - 0.38 11.2 0.0 0.78 10.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1218) DENN PF02141.16 KLO14458.1 - 2.6e-19 69.6 0.0 7.2e-19 68.2 0.0 1.8 1 0 0 1 1 1 1 DENN (AEX-3) domain YbjQ_1 PF01906.12 KLO14458.1 - 0.19 12.1 0.7 0.5 10.8 0.5 1.7 1 0 0 1 1 1 0 Putative heavy-metal-binding FHIPEP PF00771.15 KLO14458.1 - 0.21 9.9 1.3 0.34 9.1 0.9 1.2 1 0 0 1 1 1 0 FHIPEP family DUF2937 PF11157.3 KLO14458.1 - 0.24 10.7 1.4 0.89 8.8 0.9 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2937) Cortex-I_coil PF09304.5 KLO14458.1 - 0.33 10.9 10.3 0.38 10.8 3.4 2.8 2 0 0 2 2 2 0 Cortexillin I, coiled coil DUF972 PF06156.8 KLO14458.1 - 1.6 9.0 12.6 2.7 8.3 2.9 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF972) DUF4618 PF15397.1 KLO14458.1 - 5.2 6.3 12.2 1.7 7.9 5.2 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4618) Mg_trans_NIPA PF05653.9 KLO14459.1 - 1.3e-18 66.9 17.0 9.7e-10 37.8 2.0 2.4 3 0 0 3 3 3 2 Magnesium transporter NIPA EmrE PF13536.1 KLO14459.1 - 0.0013 18.8 4.3 0.0013 18.8 3.0 3.3 3 1 0 3 3 3 1 Multidrug resistance efflux transporter EamA PF00892.15 KLO14459.1 - 0.013 15.5 6.6 0.013 15.5 4.5 3.2 3 0 0 3 3 3 0 EamA-like transporter family DUF202 PF02656.10 KLO14459.1 - 4.5 7.5 14.2 5.3 7.3 2.0 3.8 3 0 0 3 3 3 0 Domain of unknown function (DUF202) zf-CHCC PF10276.4 KLO14460.1 - 2.8e-12 46.2 0.9 4.2e-12 45.6 0.6 1.2 1 0 0 1 1 1 1 Zinc-finger domain Pkinase PF00069.20 KLO14462.1 - 1.5e-56 191.4 0.0 3.3e-56 190.3 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KLO14462.1 - 5.8e-23 81.2 0.0 1.2e-22 80.2 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pribosyltran_N PF13793.1 KLO14463.1 - 7.8e-45 151.3 0.5 1.6e-41 140.6 0.0 2.3 2 0 0 2 2 2 2 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.1 KLO14463.1 - 4.2e-38 130.9 1.0 3.2e-32 111.7 0.3 2.5 1 1 1 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.22 KLO14463.1 - 5.5e-12 45.5 1.7 2.1e-11 43.6 0.5 2.2 2 0 0 2 2 2 1 Phosphoribosyl transferase domain UPRTase PF14681.1 KLO14463.1 - 0.0015 17.7 0.2 0.0029 16.8 0.1 1.5 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase SDH_sah PF01972.11 KLO14463.1 - 0.076 11.7 0.1 0.57 8.9 0.0 2.0 2 0 0 2 2 2 0 Serine dehydrogenase proteinase DCP2 PF05026.8 KLO14464.1 - 9.1e-29 99.1 4.3 1.4e-16 60.1 0.8 2.4 2 0 0 2 2 2 2 Dcp2, box A domain NUDIX PF00293.23 KLO14464.1 - 1.1e-14 54.2 0.0 1.6e-14 53.7 0.0 1.2 1 0 0 1 1 1 1 NUDIX domain DUF2223 PF09985.4 KLO14464.1 - 0.026 13.8 0.0 0.038 13.3 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF2223) AAA_2 PF07724.9 KLO14465.1 - 5.5e-49 166.3 0.0 2.1e-46 157.9 0.0 3.2 2 1 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA PF00004.24 KLO14465.1 - 6.8e-24 84.5 0.0 6.1e-13 49.1 0.0 2.9 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.4 KLO14465.1 - 7.5e-24 83.4 0.6 2.4e-23 81.8 0.1 2.3 2 0 0 2 2 1 1 C-terminal, D2-small domain, of ClpB protein AAA_5 PF07728.9 KLO14465.1 - 6.4e-15 55.1 0.7 5.9e-08 32.5 0.0 4.0 3 2 0 3 3 2 2 AAA domain (dynein-related subfamily) Clp_N PF02861.15 KLO14465.1 - 2.2e-13 49.8 9.7 4.4e-11 42.5 0.6 4.1 4 0 0 4 4 3 2 Clp amino terminal domain AAA_16 PF13191.1 KLO14465.1 - 3.7e-13 49.8 1.6 4e-05 23.6 0.0 4.9 2 2 2 5 5 5 2 AAA ATPase domain AAA_22 PF13401.1 KLO14465.1 - 5.5e-13 49.1 0.2 0.00014 22.0 0.0 4.4 3 1 1 4 4 3 2 AAA domain Sigma54_activat PF00158.21 KLO14465.1 - 1e-09 38.0 0.0 1.3e-05 24.7 0.0 3.3 3 1 0 3 3 3 2 Sigma-54 interaction domain IstB_IS21 PF01695.12 KLO14465.1 - 7.2e-08 32.0 0.0 0.00021 20.7 0.0 2.6 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_18 PF13238.1 KLO14465.1 - 1.7e-06 28.3 0.1 0.01 16.1 0.0 3.3 3 0 0 3 3 2 2 AAA domain Mg_chelatase PF01078.16 KLO14465.1 - 1.8e-06 27.2 0.1 0.0054 15.9 0.0 3.2 3 0 0 3 3 3 2 Magnesium chelatase, subunit ChlI TIP49 PF06068.8 KLO14465.1 - 4.4e-06 25.6 2.4 0.083 11.5 0.0 4.0 3 1 1 4 4 4 2 TIP49 C-terminus AAA_19 PF13245.1 KLO14465.1 - 2.2e-05 24.1 0.1 0.13 11.9 0.0 2.9 2 0 0 2 2 2 2 Part of AAA domain Zeta_toxin PF06414.7 KLO14465.1 - 4.1e-05 22.7 0.0 0.012 14.6 0.0 3.3 3 0 0 3 3 3 1 Zeta toxin AAA_24 PF13479.1 KLO14465.1 - 7.7e-05 22.3 0.0 0.014 14.9 0.0 2.4 2 0 0 2 2 2 1 AAA domain NACHT PF05729.7 KLO14465.1 - 9.3e-05 22.1 0.0 0.03 13.9 0.0 2.6 2 0 0 2 2 2 1 NACHT domain AAA_33 PF13671.1 KLO14465.1 - 0.00016 21.5 0.0 0.15 11.9 0.0 2.9 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 KLO14465.1 - 0.00019 22.2 8.9 0.3 11.9 2.8 3.9 2 2 0 2 2 2 2 AAA domain RNA_helicase PF00910.17 KLO14465.1 - 0.0002 21.4 0.1 1.5 9.0 0.0 3.0 3 0 0 3 3 2 2 RNA helicase RuvB_N PF05496.7 KLO14465.1 - 0.00062 18.8 0.2 1.3 7.9 0.0 3.7 4 0 0 4 4 4 1 Holliday junction DNA helicase ruvB N-terminus PhoH PF02562.11 KLO14465.1 - 0.0046 16.2 0.0 0.87 8.7 0.0 2.8 2 0 0 2 2 2 1 PhoH-like protein AAA_28 PF13521.1 KLO14465.1 - 0.0056 16.6 1.1 2.6 8.0 0.0 3.2 3 0 0 3 3 2 1 AAA domain AAA_10 PF12846.2 KLO14465.1 - 0.0071 15.8 0.1 4.3 6.6 0.0 3.9 2 2 1 3 3 3 0 AAA-like domain Arch_ATPase PF01637.13 KLO14465.1 - 0.011 15.4 5.4 0.34 10.5 0.0 4.2 3 2 1 5 5 4 0 Archaeal ATPase AAA_25 PF13481.1 KLO14465.1 - 0.011 15.1 2.2 7.9 5.8 0.0 4.0 3 1 1 4 4 4 0 AAA domain ABC_tran PF00005.22 KLO14465.1 - 0.023 15.0 3.2 4.1 7.7 0.0 3.7 4 0 0 4 4 3 0 ABC transporter AAA_3 PF07726.6 KLO14465.1 - 0.035 13.7 0.1 33 4.1 0.0 3.5 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) AAA_29 PF13555.1 KLO14465.1 - 0.038 13.5 0.0 7.1 6.2 0.0 2.5 2 0 0 2 2 2 0 P-loop containing region of AAA domain ResIII PF04851.10 KLO14465.1 - 0.053 13.3 0.0 5.8 6.7 0.0 3.2 3 0 0 3 3 3 0 Type III restriction enzyme, res subunit CbiA PF01656.18 KLO14465.1 - 0.061 12.7 0.0 4.7 6.5 0.0 2.8 2 0 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain MobB PF03205.9 KLO14465.1 - 0.072 12.8 0.0 9.7 5.8 0.0 2.7 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B Torsin PF06309.6 KLO14465.1 - 0.085 12.7 0.0 1.2 9.0 0.0 2.6 3 0 0 3 3 2 0 Torsin UPF0079 PF02367.12 KLO14465.1 - 0.088 12.4 0.0 14 5.3 0.0 2.5 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 DUF258 PF03193.11 KLO14465.1 - 0.13 11.4 0.0 8.5 5.5 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function, DUF258 HTH_28 PF13518.1 KLO14465.1 - 0.17 11.9 1.4 0.7 9.9 0.0 2.8 4 0 0 4 4 1 0 Helix-turn-helix domain IncA PF04156.9 KLO14465.1 - 0.54 9.8 9.9 1.5 8.3 6.8 1.7 1 0 0 1 1 1 0 IncA protein Xpo1 PF08389.7 KLO14467.1 - 3.4e-21 75.7 0.2 1.1e-19 70.7 0.0 3.1 3 0 0 3 3 3 1 Exportin 1-like protein IBN_N PF03810.14 KLO14467.1 - 2.1e-06 27.5 0.1 2.4e-05 24.1 0.0 2.7 3 0 0 3 3 3 1 Importin-beta N-terminal domain HEAT_EZ PF13513.1 KLO14467.1 - 6.2e-05 23.3 0.1 6.4 7.3 0.0 5.0 3 1 1 4 4 4 2 HEAT-like repeat CoA_binding PF02629.14 KLO14468.1 - 7.4e-29 100.1 0.1 2e-28 98.7 0.1 1.8 1 0 0 1 1 1 1 CoA binding domain Ligase_CoA PF00549.14 KLO14468.1 - 1.6e-23 83.0 0.0 2.4e-23 82.4 0.0 1.3 1 0 0 1 1 1 1 CoA-ligase Succ_CoA_lig PF13607.1 KLO14468.1 - 2.9e-09 36.6 0.0 1e-08 34.8 0.0 1.8 2 0 0 2 2 2 1 Succinyl-CoA ligase like flavodoxin domain CoA_binding_2 PF13380.1 KLO14468.1 - 2.6e-06 27.6 0.0 2.7e-05 24.2 0.0 2.5 3 0 0 3 3 3 1 CoA binding domain GFO_IDH_MocA PF01408.17 KLO14468.1 - 0.00046 20.6 0.0 0.0038 17.7 0.0 2.2 2 0 0 2 2 2 1 Oxidoreductase family, NAD-binding Rossmann fold NTPase_1 PF03266.10 KLO14468.1 - 0.063 12.9 0.0 0.14 11.8 0.0 1.7 1 0 0 1 1 1 0 NTPase ACBP PF00887.14 KLO14469.1 - 4.9e-21 74.2 0.0 8.5e-21 73.4 0.0 1.4 1 0 0 1 1 1 1 Acyl CoA binding protein Ank_2 PF12796.2 KLO14469.1 - 2.6e-12 46.8 0.0 4.9e-12 46.0 0.0 1.4 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.1 KLO14469.1 - 3.1e-12 46.6 0.0 1.3e-06 28.7 0.0 2.4 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.25 KLO14469.1 - 9.6e-12 44.0 0.1 4e-10 38.9 0.0 2.6 2 0 0 2 2 2 1 Ankyrin repeat Ank_5 PF13857.1 KLO14469.1 - 1.5e-10 40.9 0.0 3.2e-10 39.9 0.0 1.6 1 1 0 1 1 1 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 KLO14469.1 - 2e-08 33.6 0.0 1.4e-07 31.0 0.0 2.2 2 0 0 2 2 2 1 Ankyrin repeat CP12 PF02672.10 KLO14469.1 - 0.028 14.8 1.0 0.1 13.0 0.2 2.3 2 1 0 2 2 2 0 CP12 domain Ribosomal_S16 PF00886.14 KLO14470.1 - 2.1e-20 72.2 0.1 2.9e-20 71.7 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S16 LSM PF01423.17 KLO14471.1 - 2.9e-20 71.5 0.1 3.3e-20 71.3 0.0 1.0 1 0 0 1 1 1 1 LSM domain Arm PF00514.18 KLO14472.1 - 1.7e-90 294.1 13.6 5.7e-13 48.1 0.0 8.3 8 0 0 8 8 8 8 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 KLO14472.1 - 2.4e-25 88.6 0.1 1.8e-09 37.7 0.0 5.4 1 1 4 5 5 5 5 HEAT repeats HEAT_EZ PF13513.1 KLO14472.1 - 1e-24 86.2 4.3 2.4e-09 37.3 0.1 5.6 5 0 0 5 5 5 4 HEAT-like repeat IBB PF01749.15 KLO14472.1 - 9e-22 77.0 2.3 1.5e-21 76.3 1.6 1.4 1 0 0 1 1 1 1 Importin beta binding domain HEAT PF02985.17 KLO14472.1 - 7e-17 59.9 0.9 9.4e-06 25.2 0.0 6.7 7 0 0 7 7 6 2 HEAT repeat Arm_2 PF04826.8 KLO14472.1 - 4.2e-08 32.5 0.0 0.0098 15.0 0.0 4.0 2 1 2 4 4 4 3 Armadillo-like Adaptin_N PF01602.15 KLO14472.1 - 5.6e-08 31.5 0.0 4.1e-06 25.4 0.0 2.7 1 1 1 2 2 2 1 Adaptin N terminal region V-ATPase_H_C PF11698.3 KLO14472.1 - 1.7e-05 24.7 0.0 0.11 12.3 0.0 4.5 3 1 0 4 4 4 1 V-ATPase subunit H RICTOR_V PF14668.1 KLO14472.1 - 1.8e-05 24.5 2.2 0.54 10.2 0.0 4.5 4 1 1 5 5 4 2 Rapamycin-insensitive companion of mTOR, domain 5 HEAT_PBS PF03130.11 KLO14472.1 - 0.0015 18.7 4.2 0.62 10.6 0.1 4.6 5 0 0 5 5 5 1 PBS lyase HEAT-like repeat Mo25 PF08569.6 KLO14472.1 - 0.0016 17.5 0.0 0.004 16.2 0.0 1.6 2 0 0 2 2 2 1 Mo25-like Proteasom_PSMB PF10508.4 KLO14472.1 - 0.012 13.9 0.1 0.11 10.6 0.0 2.1 1 1 1 2 2 2 0 Proteasome non-ATPase 26S subunit V-ATPase_H_N PF03224.9 KLO14472.1 - 0.056 12.5 0.0 3.2 6.7 0.0 3.0 1 1 0 2 2 2 0 V-ATPase subunit H Fungal_trans PF04082.13 KLO14473.1 - 1.9e-14 53.2 0.7 2.8e-14 52.6 0.5 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KLO14473.1 - 2.9e-06 27.0 12.2 5.7e-06 26.1 8.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PDT PF00800.13 KLO14474.1 - 1.6e-52 177.7 0.1 2e-52 177.3 0.1 1.1 1 0 0 1 1 1 1 Prephenate dehydratase p450 PF00067.17 KLO14475.1 - 8.3e-67 225.6 0.0 9.5e-67 225.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Fungal_trans PF04082.13 KLO14477.1 - 7.1e-09 34.9 0.1 1.3e-08 34.0 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KLO14477.1 - 7.4e-06 25.7 11.1 1.4e-05 24.9 7.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain UPF0047 PF01894.12 KLO14478.1 - 1.6e-42 144.0 0.1 1.8e-42 143.8 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family UPF0047 TTL PF03133.10 KLO14479.1 - 4.6e-50 170.2 0.0 6.2e-50 169.7 0.0 1.1 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family ATP-grasp_4 PF13535.1 KLO14479.1 - 0.034 13.8 0.0 0.073 12.7 0.0 1.5 1 0 0 1 1 1 0 ATP-grasp domain DUF2404 PF10296.4 KLO14480.1 - 0.00015 21.8 0.0 0.00036 20.5 0.0 1.7 1 0 0 1 1 1 1 Putative integral membrane protein conserved region (DUF2404) RNA_pol_Rpb8 PF03870.10 KLO14481.1 - 1.4e-42 145.1 1.0 5.4e-42 143.2 0.7 1.7 1 1 0 1 1 1 1 RNA polymerase Rpb8 Porin_OmpG PF09381.5 KLO14481.1 - 0.087 11.8 0.2 0.15 11.1 0.1 1.5 1 1 0 1 1 1 0 Outer membrane protein G (OmpG) Con-6 PF10346.4 KLO14482.1 - 4.2e-35 118.8 3.8 1.7e-18 65.7 0.4 2.1 2 0 0 2 2 2 2 Conidiation protein 6 DUF896 PF05979.7 KLO14482.1 - 0.058 12.9 0.0 0.11 12.1 0.0 1.4 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF896) RelB PF04221.7 KLO14482.1 - 0.066 12.9 0.0 6.9 6.5 0.0 2.2 2 0 0 2 2 2 0 RelB antitoxin Con-6 PF10346.4 KLO14483.1 - 2.9e-27 93.7 6.1 3.2e-13 48.8 0.3 2.1 2 0 0 2 2 2 2 Conidiation protein 6 Acp26Ab PF05777.7 KLO14483.1 - 0.27 11.7 1.4 1.4 9.4 0.7 1.8 1 1 1 2 2 2 0 Drosophila accessory gland-specific peptide 26Ab (Acp26Ab) INCENP_ARK-bind PF03941.10 KLO14484.1 - 6.9e-15 54.6 0.9 6.9e-15 54.6 0.6 2.5 2 0 0 2 2 2 1 Inner centromere protein, ARK binding region TPR_12 PF13424.1 KLO14485.1 - 5.1e-13 48.7 0.2 1e-12 47.8 0.1 1.4 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_10 PF13374.1 KLO14485.1 - 5.9e-10 38.7 0.2 0.00057 19.7 0.0 2.4 2 0 0 2 2 2 2 Tetratricopeptide repeat zf-MYND PF01753.13 KLO14485.1 - 2.1e-09 37.0 4.6 3.2e-09 36.5 3.2 1.3 1 0 0 1 1 1 1 MYND finger TPR_1 PF00515.23 KLO14485.1 - 4.2e-07 29.3 0.1 0.0023 17.4 0.0 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.1 KLO14485.1 - 1.6e-06 27.6 0.9 0.005 16.4 0.2 2.3 2 0 0 2 2 2 2 TPR repeat TPR_2 PF07719.12 KLO14485.1 - 4.1e-06 26.3 0.1 0.15 12.0 0.0 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.1 KLO14485.1 - 2.1e-05 23.9 0.5 0.3 11.0 0.1 2.4 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.1 KLO14485.1 - 2.9e-05 24.5 0.6 8.2e-05 23.1 0.4 1.7 1 1 0 1 1 1 1 Tetratricopeptide repeat TPR_4 PF07721.9 KLO14485.1 - 0.0077 16.5 0.0 1.4 9.5 0.0 2.8 3 0 0 3 3 2 1 Tetratricopeptide repeat TPR_19 PF14559.1 KLO14485.1 - 0.016 15.5 0.6 0.051 13.9 0.4 1.8 1 1 0 1 1 1 0 Tetratricopeptide repeat Ecl1 PF12855.2 KLO14485.1 - 0.03 13.5 1.2 0.065 12.5 0.9 1.5 1 0 0 1 1 1 0 Life-span regulatory factor TPR_14 PF13428.1 KLO14485.1 - 0.068 13.8 1.9 4.8 8.0 0.3 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_8 PF13181.1 KLO14485.1 - 0.075 12.8 0.1 0.68 9.8 0.0 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.1 KLO14486.1 - 3e-15 55.9 9.0 3.5e-13 49.2 1.3 2.1 1 1 1 2 2 2 2 Tetratricopeptide repeat zf-MYND PF01753.13 KLO14486.1 - 2.2e-09 37.0 9.4 4.4e-09 36.0 6.5 1.5 1 0 0 1 1 1 1 MYND finger TPR_10 PF13374.1 KLO14486.1 - 4.7e-09 35.8 11.1 7.4e-05 22.5 0.9 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.1 KLO14486.1 - 1.5e-07 30.9 3.0 0.00055 19.5 0.9 2.2 2 0 0 2 2 2 2 TPR repeat TPR_1 PF00515.23 KLO14486.1 - 1.6e-06 27.4 1.2 0.038 13.5 0.0 3.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.12 KLO14486.1 - 1.3e-05 24.7 4.4 0.16 11.9 0.1 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.1 KLO14486.1 - 0.00013 22.5 1.7 0.00013 22.5 1.2 2.0 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_17 PF13431.1 KLO14486.1 - 0.00026 20.9 1.1 1.3 9.4 0.0 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_4 PF07721.9 KLO14486.1 - 0.0028 17.9 1.0 2.1 9.0 0.0 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.1 KLO14486.1 - 0.0032 17.1 5.9 0.27 11.1 0.1 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.1 KLO14486.1 - 0.018 14.8 0.4 0.29 11.0 0.0 2.7 3 0 0 3 3 3 0 Tetratricopeptide repeat Cytochrom_C552 PF02335.10 KLO14486.1 - 0.043 12.5 0.4 0.062 11.9 0.3 1.3 1 0 0 1 1 1 0 Cytochrome c552 TPR_19 PF14559.1 KLO14486.1 - 0.55 10.6 3.3 0.34 11.2 0.3 2.0 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.1 KLO14486.1 - 1 10.1 6.1 16 6.4 0.3 2.9 1 1 2 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.1 KLO14487.1 - 7.4e-15 54.6 8.7 1e-12 47.7 3.1 2.1 1 1 0 2 2 2 2 Tetratricopeptide repeat TPR_10 PF13374.1 KLO14487.1 - 3.4e-10 39.5 11.0 0.00013 21.8 0.6 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat zf-MYND PF01753.13 KLO14487.1 - 4.8e-09 35.9 8.3 8.9e-09 35.0 5.8 1.5 1 0 0 1 1 1 1 MYND finger TPR_11 PF13414.1 KLO14487.1 - 4.3e-07 29.4 8.8 0.00093 18.8 2.5 2.2 1 1 0 2 2 2 2 TPR repeat TPR_2 PF07719.12 KLO14487.1 - 6.1e-07 28.8 5.2 0.034 14.0 0.2 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.23 KLO14487.1 - 3e-06 26.5 2.1 0.021 14.4 0.1 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.1 KLO14487.1 - 8.9e-06 26.2 3.3 8.9e-06 26.2 2.3 2.1 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_17 PF13431.1 KLO14487.1 - 7.4e-05 22.6 1.9 0.53 10.6 0.0 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.1 KLO14487.1 - 0.00021 20.8 6.4 0.075 12.8 0.1 2.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.1 KLO14487.1 - 0.00047 19.7 1.0 0.06 13.1 0.0 3.0 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_4 PF07721.9 KLO14487.1 - 0.0011 19.1 1.3 2 9.1 0.1 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.1 KLO14487.1 - 0.036 14.7 6.4 2.5 8.9 0.8 3.1 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_19 PF14559.1 KLO14487.1 - 0.062 13.6 6.5 0.13 12.6 1.0 2.5 1 1 1 2 2 2 0 Tetratricopeptide repeat Apc3 PF12895.2 KLO14487.1 - 0.49 10.5 2.8 1.2 9.3 0.3 2.1 1 1 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 DUF4398 PF14346.1 KLO14487.1 - 2.6 8.1 8.5 22 5.1 0.0 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4398) Septin PF00735.13 KLO14488.1 - 4.3e-124 413.0 0.2 4.3e-124 413.0 0.1 1.5 2 0 0 2 2 2 1 Septin MMR_HSR1 PF01926.18 KLO14488.1 - 1.4e-07 31.5 0.0 3.3e-07 30.2 0.0 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase DUF258 PF03193.11 KLO14488.1 - 1.1e-06 27.9 0.0 2.6e-06 26.7 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function, DUF258 GTP_EFTU PF00009.22 KLO14488.1 - 9.9e-05 21.8 0.1 0.0024 17.3 0.0 2.7 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain ABC_tran PF00005.22 KLO14488.1 - 0.00051 20.3 4.0 0.0029 17.9 0.2 2.6 2 1 0 2 2 2 1 ABC transporter AIG1 PF04548.11 KLO14488.1 - 0.00068 18.8 0.0 0.002 17.2 0.0 1.8 1 0 0 1 1 1 1 AIG1 family AAA_22 PF13401.1 KLO14488.1 - 0.00072 19.7 0.0 0.0036 17.4 0.0 2.2 2 1 0 2 2 2 1 AAA domain Ras PF00071.17 KLO14488.1 - 0.0026 17.1 0.1 0.0091 15.4 0.0 1.9 2 0 0 2 2 2 1 Ras family AAA_10 PF12846.2 KLO14488.1 - 0.0054 16.2 0.0 0.011 15.2 0.0 1.5 1 0 0 1 1 1 1 AAA-like domain Dynamin_N PF00350.18 KLO14488.1 - 0.0058 16.4 4.1 0.45 10.3 0.1 3.1 2 1 1 3 3 3 2 Dynamin family AAA_16 PF13191.1 KLO14488.1 - 0.01 15.8 0.4 0.11 12.4 0.0 2.3 2 0 0 2 2 2 0 AAA ATPase domain PduV-EutP PF10662.4 KLO14488.1 - 0.011 15.2 0.0 4.8 6.6 0.0 2.8 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation Miro PF08477.8 KLO14488.1 - 0.012 16.0 0.0 0.067 13.6 0.0 2.2 2 0 0 2 2 2 0 Miro-like protein AAA_29 PF13555.1 KLO14488.1 - 0.052 13.0 0.0 0.11 12.0 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain MobB PF03205.9 KLO14488.1 - 0.061 13.0 0.0 0.15 11.7 0.0 1.7 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B ATP_bind_1 PF03029.12 KLO14488.1 - 0.066 12.7 0.2 5.9 6.3 0.0 2.7 2 1 0 3 3 3 0 Conserved hypothetical ATP binding protein Exonuc_VII_L PF02601.10 KLO14488.1 - 0.65 9.1 5.9 1.5 7.9 4.1 1.5 1 0 0 1 1 1 0 Exonuclease VII, large subunit IncA PF04156.9 KLO14488.1 - 0.85 9.1 6.0 1.7 8.2 4.2 1.5 1 0 0 1 1 1 0 IncA protein CN_hydrolase PF00795.17 KLO14490.1 - 2.4e-32 111.7 0.0 3.4e-32 111.3 0.0 1.2 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase MRP-S28 PF10213.4 KLO14491.1 - 1.2e-26 93.2 0.0 1.6e-26 92.8 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal subunit protein DUF866 PF05907.8 KLO14492.1 - 3.3e-46 156.7 0.0 3.7e-46 156.5 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF866) Cytochrome_C7 PF14522.1 KLO14492.1 - 0.0066 16.0 1.0 0.012 15.2 0.7 1.4 1 0 0 1 1 1 1 Cytochrome c7 Terminase_GpA PF05876.7 KLO14492.1 - 0.15 10.3 1.4 1.5 7.0 1.2 1.8 1 1 1 2 2 2 0 Phage terminase large subunit (GpA) Lar_restr_allev PF14354.1 KLO14492.1 - 0.3 11.4 0.2 0.3 11.4 0.2 2.4 2 1 1 3 3 3 0 Restriction alleviation protein Lar Zn-ribbon_8 PF09723.5 KLO14492.1 - 0.49 10.3 4.2 0.31 11.0 0.4 2.2 1 1 1 2 2 2 0 Zinc ribbon domain IQ PF00612.22 KLO14493.1 - 0.0074 15.8 0.0 0.0074 15.8 0.0 1.9 2 0 0 2 2 2 1 IQ calmodulin-binding motif Pkinase PF00069.20 KLO14494.1 - 8.1e-66 221.8 0.0 1.4e-65 221.0 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KLO14494.1 - 2.1e-44 151.5 0.0 3.7e-44 150.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KLO14494.1 - 6.7e-10 38.3 0.0 6.7e-08 31.8 0.0 2.2 2 0 0 2 2 2 2 Kinase-like Kdo PF06293.9 KLO14494.1 - 0.028 13.5 0.0 0.06 12.4 0.0 1.5 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.6 KLO14494.1 - 0.86 8.3 0.0 1.4 7.6 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 CLTH PF10607.4 KLO14495.1 - 7.5e-36 122.9 0.0 1.3e-35 122.1 0.0 1.4 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain Rrp15p PF07890.7 KLO14495.1 - 2.1e-18 66.5 3.3 2.1e-18 66.5 2.3 2.1 1 1 1 2 2 2 1 Rrp15p LisH PF08513.6 KLO14495.1 - 7e-09 35.1 1.5 8.9e-09 34.8 0.2 1.9 2 0 0 2 2 2 1 LisH NST1 PF13945.1 KLO14495.1 - 0.016 15.3 2.8 0.028 14.4 1.9 1.5 1 0 0 1 1 1 0 Salt tolerance down-regulator DIL PF01843.14 KLO14496.1 - 1.8e-20 72.7 0.0 4e-20 71.6 0.0 1.6 1 0 0 1 1 1 1 DIL domain Ank_4 PF13637.1 KLO14496.1 - 3.9e-11 43.1 0.4 1.5e-05 25.3 0.0 5.4 5 1 1 6 6 6 2 Ankyrin repeats (many copies) Ank_2 PF12796.2 KLO14496.1 - 1.3e-09 38.2 0.0 6e-09 36.1 0.0 2.1 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank PF00023.25 KLO14496.1 - 3.9e-08 32.7 0.3 0.002 17.8 0.1 2.8 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.1 KLO14496.1 - 6.3e-07 29.4 0.4 2.6e-05 24.3 0.1 2.9 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 KLO14496.1 - 6.2e-05 22.8 2.4 0.0024 17.9 0.1 3.9 4 0 0 4 4 4 1 Ankyrin repeat SnoaL PF07366.7 KLO14497.1 - 6.7e-06 25.7 0.0 1.2e-05 24.9 0.0 1.3 1 0 0 1 1 1 1 SnoaL-like polyketide cyclase SnoaL_2 PF12680.2 KLO14497.1 - 0.01 16.1 0.0 0.02 15.2 0.0 1.4 1 0 0 1 1 1 0 SnoaL-like domain Rhomboid PF01694.17 KLO14498.1 - 7.8e-36 123.2 15.1 7.8e-36 123.2 10.5 1.8 3 0 0 3 3 3 1 Rhomboid family DUF1426 PF07234.6 KLO14498.1 - 0.2 11.3 0.2 0.2 11.3 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1426) DUF4191 PF13829.1 KLO14498.1 - 9.2 5.3 5.9 21 4.1 0.1 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4191) DUF2372 PF10178.4 KLO14500.1 - 0.032 14.3 0.1 0.12 12.5 0.0 2.0 1 1 0 1 1 1 0 Uncharacterised conserved protein (DUF2372) DUF605 PF04652.11 KLO14503.1 - 8.2 5.7 12.2 11 5.2 8.5 1.2 1 0 0 1 1 1 0 Vta1 like AT_hook PF02178.14 KLO14504.1 - 0.081 12.6 0.3 0.081 12.6 0.2 2.5 2 0 0 2 2 2 0 AT hook motif DUF746 PF05344.6 KLO14505.1 - 0.054 13.0 0.1 0.24 10.9 0.0 2.2 2 0 0 2 2 2 0 Domain of Unknown Function (DUF746) Ham1p_like PF01725.11 KLO14506.1 - 3e-53 180.0 0.0 3.3e-53 179.8 0.0 1.0 1 0 0 1 1 1 1 Ham1 family Rab5ip PF07019.7 KLO14507.1 - 5.5e-13 48.8 2.8 7.4e-13 48.4 1.9 1.1 1 0 0 1 1 1 1 Rab5-interacting protein (Rab5ip) TPR_11 PF13414.1 KLO14509.1 - 1.1e-16 60.1 0.3 3.7e-07 29.7 0.0 5.6 4 1 1 5 5 5 3 TPR repeat TPR_12 PF13424.1 KLO14509.1 - 9e-11 41.5 0.5 0.00063 19.6 0.0 5.8 4 1 2 6 6 6 2 Tetratricopeptide repeat TPR_17 PF13431.1 KLO14509.1 - 7e-10 38.3 0.0 0.015 15.4 0.0 4.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.23 KLO14509.1 - 3.6e-09 35.8 0.0 0.27 10.9 0.0 5.5 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_2 PF07719.12 KLO14509.1 - 1.8e-08 33.6 7.0 0.076 12.9 0.0 6.7 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_16 PF13432.1 KLO14509.1 - 5.6e-07 30.0 4.5 0.0017 18.9 0.0 5.0 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_14 PF13428.1 KLO14509.1 - 1.5e-05 25.1 6.3 2.9 8.7 0.0 6.6 4 2 3 7 7 7 1 Tetratricopeptide repeat TPR_8 PF13181.1 KLO14509.1 - 0.031 14.0 0.0 76 3.4 0.0 4.6 3 2 1 4 4 4 0 Tetratricopeptide repeat TPR_10 PF13374.1 KLO14509.1 - 0.19 11.7 4.8 23 5.1 0.0 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat SH3_9 PF14604.1 KLO14510.1 - 2.5e-15 55.7 0.1 4.8e-15 54.8 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain PH PF00169.24 KLO14510.1 - 1.3e-14 54.2 0.2 5.1e-14 52.3 0.0 2.0 2 0 0 2 2 2 1 PH domain SH3_1 PF00018.23 KLO14510.1 - 4e-12 45.3 0.2 8.4e-12 44.2 0.2 1.6 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 KLO14510.1 - 1.9e-09 36.8 0.1 3.6e-09 35.9 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SAM_2 PF07647.12 KLO14510.1 - 1e-08 34.8 0.0 1.8e-08 34.0 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.25 KLO14510.1 - 2.3e-06 27.6 0.0 5e-06 26.5 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) PH_11 PF15413.1 KLO14510.1 - 0.00059 20.0 1.5 0.00084 19.5 0.3 1.9 2 0 0 2 2 2 1 Pleckstrin homology domain Ste50p-SAM PF09235.5 KLO14510.1 - 0.08 12.9 0.2 0.16 12.0 0.2 1.4 1 0 0 1 1 1 0 Ste50p, sterile alpha motif AAA_23 PF13476.1 KLO14511.1 - 9.3e-18 65.2 0.0 9.3e-18 65.2 0.0 5.3 2 2 1 3 3 3 1 AAA domain SMC_N PF02463.14 KLO14511.1 - 4.4e-17 62.0 18.3 2.9e-16 59.3 12.7 2.3 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 KLO14511.1 - 0.0028 17.6 0.0 0.0028 17.6 0.0 3.4 3 1 0 3 3 3 1 AAA domain AAA_29 PF13555.1 KLO14511.1 - 0.0062 16.0 0.0 0.015 14.7 0.0 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_25 PF13481.1 KLO14511.1 - 0.011 15.0 1.6 0.15 11.4 0.0 3.0 2 1 0 2 2 2 0 AAA domain ABC_tran PF00005.22 KLO14511.1 - 0.1 12.9 0.1 0.1 12.9 0.1 4.3 3 2 1 4 4 4 0 ABC transporter AAA_13 PF13166.1 KLO14511.1 - 0.12 10.7 0.0 0.12 10.7 0.0 4.5 3 1 0 3 3 3 0 AAA domain RNase_PH PF01138.16 KLO14512.1 - 1.6e-26 93.1 0.0 3e-26 92.2 0.0 1.5 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.10 KLO14512.1 - 7.3e-07 29.0 0.0 1.2e-06 28.3 0.0 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 UAF_Rrn10 PF05234.6 KLO14513.1 - 0.032 14.2 0.0 3.3 7.7 0.0 2.4 2 0 0 2 2 2 0 UAF complex subunit Rrn10 Ribosomal_L13 PF00572.13 KLO14514.1 - 7e-48 161.8 0.1 8.6e-48 161.6 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L13 Pkinase PF00069.20 KLO14515.1 - 2e-60 204.1 0.0 2.5e-60 203.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KLO14515.1 - 6.2e-29 100.8 0.0 9.4e-29 100.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KLO14515.1 - 0.0015 17.5 0.0 0.0024 16.9 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 KLO14515.1 - 0.022 14.5 0.4 0.75 9.4 0.0 2.8 1 1 0 3 3 3 0 Phosphotransferase enzyme family Pkinase PF00069.20 KLO14516.1 - 9.8e-61 205.1 0.0 1.3e-60 204.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KLO14516.1 - 5.2e-29 101.1 0.0 1.5e-28 99.5 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KLO14516.1 - 0.0022 17.0 0.0 0.004 16.1 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 KLO14516.1 - 0.044 13.5 0.2 0.47 10.1 0.0 2.4 3 0 0 3 3 3 0 Phosphotransferase enzyme family F-box-like PF12937.2 KLO14517.1 - 1.1e-06 28.1 0.0 1.5e-05 24.5 0.0 3.0 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 KLO14517.1 - 0.061 12.9 0.0 0.18 11.4 0.0 1.8 1 0 0 1 1 1 0 F-box domain YXWGXW PF12779.2 KLO14519.1 - 0.0055 16.5 2.1 0.011 15.5 1.4 1.5 1 0 0 1 1 1 1 YXWGXW repeat (2 copies) Peptidase_M24 PF00557.19 KLO14520.1 - 4.7e-47 160.2 0.0 5.5e-47 160.0 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 Nup188 PF10487.4 KLO14521.1 - 1.2e-25 89.7 0.1 5.4e-24 84.2 0.1 2.5 2 1 0 2 2 2 2 Nucleoporin subcomplex protein binding to Pom34 Semialdhyde_dhC PF02774.13 KLO14522.1 - 2.1e-33 115.7 0.0 3.8e-33 114.8 0.0 1.4 1 1 0 1 1 1 1 Semialdehyde dehydrogenase, dimerisation domain Semialdhyde_dh PF01118.19 KLO14522.1 - 2.6e-28 98.7 0.0 4.2e-28 98.0 0.0 1.3 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain DXP_reductoisom PF02670.11 KLO14522.1 - 0.015 15.8 0.0 0.039 14.5 0.0 1.7 1 0 0 1 1 1 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase DapB_N PF01113.15 KLO14522.1 - 0.11 12.4 0.0 0.19 11.6 0.0 1.4 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus TAF4 PF05236.9 KLO14523.1 - 4.5e-24 85.1 16.8 3.8e-19 69.0 0.9 2.7 2 1 0 2 2 2 2 Transcription initiation factor TFIID component TAF4 family SAGA-Tad1 PF12767.2 KLO14523.1 - 0.00074 19.2 0.5 0.00074 19.2 0.4 2.8 3 1 0 3 3 3 1 Transcriptional regulator of RNA polII, SAGA, subunit Calc_CGRP_IAPP PF00214.14 KLO14523.1 - 0.17 11.9 1.8 0.38 10.8 0.2 2.3 1 1 1 2 2 2 0 Calcitonin / CGRP / IAPP family zf-CCCH PF00642.19 KLO14524.1 - 0.084 12.5 2.0 0.15 11.7 1.4 1.4 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Nucleoporin_FG PF13634.1 KLO14524.1 - 0.76 10.0 134.2 0.042 14.0 28.3 6.0 2 1 2 4 4 4 0 Nucleoporin FG repeat region FAM194 PF14977.1 KLO14525.1 - 0.0019 17.2 0.0 0.0051 15.8 0.0 1.6 1 1 1 2 2 2 1 FAM194 protein zf-CCHC PF00098.18 KLO14526.1 - 1.6e-30 103.5 53.6 1.1e-07 31.4 1.3 7.2 7 0 0 7 7 7 6 Zinc knuckle zf-CCHC_3 PF13917.1 KLO14526.1 - 5.2e-07 29.2 34.4 0.058 13.1 0.4 6.2 3 1 3 6 6 6 5 Zinc knuckle zf-CCHC_4 PF14392.1 KLO14526.1 - 2.1e-06 27.3 43.4 0.049 13.2 2.2 6.6 6 1 1 7 7 7 5 Zinc knuckle zf-CCHC_2 PF13696.1 KLO14526.1 - 0.06 12.8 0.7 0.06 12.8 0.5 6.8 5 2 2 7 7 7 0 Zinc knuckle zf-CCHC_5 PF14787.1 KLO14526.1 - 0.22 11.0 0.3 0.22 11.0 0.2 4.9 3 1 1 4 4 4 0 GAG-polyprotein viral zinc-finger Polyketide_cyc PF03364.15 KLO14527.1 - 6.1e-22 78.0 0.0 7.9e-22 77.6 0.0 1.1 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Nol1_Nop2_Fmu PF01189.12 KLO14529.1 - 5.3e-101 337.7 0.0 7.6e-101 337.2 0.0 1.2 1 0 0 1 1 1 1 NOL1/NOP2/sun family PCMT PF01135.14 KLO14529.1 - 0.0032 17.0 0.0 0.0053 16.3 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Met_10 PF02475.11 KLO14529.1 - 0.0039 16.8 0.0 0.0067 16.0 0.0 1.3 1 0 0 1 1 1 1 Met-10+ like-protein FtsJ PF01728.14 KLO14529.1 - 0.011 15.6 0.0 0.024 14.6 0.0 1.6 1 0 0 1 1 1 0 FtsJ-like methyltransferase Methyltransf_31 PF13847.1 KLO14529.1 - 0.041 13.4 0.0 0.079 12.5 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Aminotran_1_2 PF00155.16 KLO14530.1 - 1.5e-17 63.5 0.0 9.6e-13 47.8 0.0 2.1 2 0 0 2 2 2 2 Aminotransferase class I and II Sua5_yciO_yrdC PF01300.13 KLO14531.1 - 9e-56 187.9 0.0 1.4e-55 187.3 0.0 1.3 1 0 0 1 1 1 1 Telomere recombination SUA5 PF03481.8 KLO14531.1 - 1.7e-25 89.4 0.0 2.9e-25 88.7 0.0 1.4 1 0 0 1 1 1 1 Putative GTP-binding controlling metal-binding DEAD PF00270.24 KLO14532.1 - 1.8e-43 147.9 0.0 2.9e-43 147.3 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KLO14532.1 - 2.9e-25 87.9 0.0 7.5e-25 86.6 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 KLO14532.1 - 0.0025 17.6 0.0 0.0064 16.3 0.0 1.7 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit Ribosomal_L14e PF01929.12 KLO14532.1 - 0.041 14.2 0.3 0.092 13.1 0.2 1.5 1 0 0 1 1 1 0 Ribosomal protein L14 Helitron_like_N PF14214.1 KLO14533.1 - 1.1e-41 142.6 0.1 5e-41 140.4 0.1 2.0 1 1 0 1 1 1 1 Helitron helicase-like domain at N-terminus UCH PF00443.24 KLO14535.1 - 1.5e-29 103.0 0.0 2.1e-29 102.4 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 KLO14535.1 - 1.3e-10 41.2 0.0 5.7e-10 39.1 0.0 1.9 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase COG7 PF10191.4 KLO14536.1 - 5.2e-67 226.3 0.2 9.2e-40 136.2 0.5 3.2 3 0 0 3 3 3 3 Golgi complex component 7 (COG7) Vps53_N PF04100.7 KLO14536.1 - 0.0039 16.0 0.2 0.0076 15.0 0.2 1.4 1 0 0 1 1 1 1 Vps53-like, N-terminal DUF1664 PF07889.7 KLO14536.1 - 0.099 12.4 0.1 2 8.2 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) GST_N PF02798.15 KLO14538.1 - 3.2e-15 56.0 0.0 7.1e-15 54.9 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 KLO14538.1 - 2.1e-12 47.0 0.0 4e-12 46.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 KLO14538.1 - 4.8e-11 42.5 0.0 7.6e-11 41.8 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 KLO14538.1 - 3.1e-09 36.7 0.0 5.9e-09 35.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 KLO14538.1 - 8.3e-08 32.0 0.0 1.2e-07 31.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 KLO14538.1 - 0.00048 20.5 0.0 0.00091 19.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 KLO14539.1 - 3.2e-20 72.0 0.0 5.5e-20 71.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 KLO14539.1 - 1.1e-14 54.4 0.0 2.1e-14 53.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 KLO14539.1 - 2.6e-13 49.7 0.0 4.3e-13 49.0 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 KLO14539.1 - 1.4e-10 41.0 0.0 2.2e-10 40.3 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 KLO14539.1 - 2.1e-09 37.1 0.1 3.8e-09 36.2 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 KLO14539.1 - 0.0011 19.3 0.0 0.0017 18.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 KLO14541.1 - 2.6e-15 56.3 0.0 4.5e-15 55.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 KLO14541.1 - 1.2e-13 51.0 0.0 2.2e-13 50.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 KLO14541.1 - 2.3e-11 43.5 0.0 4.5e-11 42.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 KLO14541.1 - 8e-09 35.2 0.2 1.5e-08 34.4 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 KLO14541.1 - 2.9e-08 33.6 0.0 5.1e-08 32.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 KLO14541.1 - 0.00044 20.6 0.0 0.00064 20.1 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain DUF1912 PF08930.5 KLO14541.1 - 0.052 13.6 0.1 0.11 12.6 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1912) GST_N_3 PF13417.1 KLO14542.1 - 5.8e-13 48.8 0.0 1.1e-12 47.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 KLO14542.1 - 5.3e-12 45.7 0.0 8.6e-12 45.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 KLO14542.1 - 7.6e-10 38.6 0.0 1.2e-09 37.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 KLO14542.1 - 8.4e-09 35.3 0.0 1.4e-08 34.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 KLO14542.1 - 9.8e-08 31.7 0.5 3.7e-07 29.9 0.3 2.0 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 KLO14542.1 - 0.003 17.9 0.0 0.0045 17.4 0.0 1.4 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Peptidase_M4_C PF02868.10 KLO14545.1 - 3.6e-36 124.3 0.1 4.7e-36 123.9 0.0 1.2 1 0 0 1 1 1 1 Thermolysin metallopeptidase, alpha-helical domain Peptidase_M4 PF01447.13 KLO14545.1 - 1.4e-26 93.4 1.2 2.1e-26 92.8 0.8 1.3 1 0 0 1 1 1 1 Thermolysin metallopeptidase, catalytic domain Peptidase_MA_2 PF13485.1 KLO14545.1 - 0.011 15.7 0.0 0.2 11.6 0.0 2.1 2 0 0 2 2 2 0 Peptidase MA superfamily Peptidase_M13 PF01431.16 KLO14545.1 - 0.016 14.3 0.3 0.029 13.5 0.2 1.3 1 0 0 1 1 1 0 Peptidase family M13 F-box-like PF12937.2 KLO14546.1 - 1.4e-08 34.2 0.3 3.9e-08 32.9 0.2 1.8 1 0 0 1 1 1 1 F-box-like XPC-binding PF09280.6 KLO14546.1 - 0.035 13.5 0.0 0.16 11.4 0.0 2.1 2 0 0 2 2 2 0 XPC-binding domain GABP-alpha PF11620.3 KLO14546.1 - 0.057 13.4 0.0 0.19 11.7 0.0 1.8 1 0 0 1 1 1 0 GA-binding protein alpha chain F-box PF00646.28 KLO14546.1 - 0.22 11.2 2.7 5.7 6.7 0.0 2.8 2 0 0 2 2 2 0 F-box domain Tyrosinase PF00264.15 KLO14547.1 - 1.9e-50 172.1 0.8 3.2e-50 171.3 0.5 1.4 1 0 0 1 1 1 1 Common central domain of tyrosinase Pkinase PF00069.20 KLO14549.1 - 1.9e-40 138.6 0.0 1.2e-21 77.0 0.0 3.1 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 KLO14549.1 - 3.6e-12 45.9 0.0 1.8e-09 37.0 0.0 2.9 2 1 0 2 2 2 2 Protein tyrosine kinase APH PF01636.18 KLO14549.1 - 0.033 13.9 2.6 0.038 13.7 0.1 2.3 3 0 0 3 3 3 0 Phosphotransferase enzyme family Vps36_ESCRT-II PF11605.3 KLO14550.1 - 0.051 13.3 0.0 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 Vacuolar protein sorting protein 36 Vps36 bPH_3 PF14470.1 KLO14550.1 - 0.068 13.4 0.0 0.11 12.8 0.0 1.3 1 0 0 1 1 1 0 Bacterial PH domain RRP7 PF12923.2 KLO14551.1 - 3.1e-34 117.8 7.3 3.1e-34 117.8 5.1 2.1 2 0 0 2 2 2 1 Ribosomal RNA-processing protein 7 (RRP7) RRM_1 PF00076.17 KLO14551.1 - 2.8e-05 23.6 0.0 0.0013 18.3 0.0 2.6 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KLO14551.1 - 0.0019 18.1 0.1 0.07 13.1 0.0 2.8 3 0 0 3 3 3 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) DUF2890 PF11081.3 KLO14551.1 - 0.018 15.0 2.0 0.018 15.0 1.4 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2890) DUF4637 PF15470.1 KLO14551.1 - 0.67 9.5 4.9 1.2 8.7 3.0 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4637) Med8 PF10232.4 KLO14551.1 - 1.9 7.9 5.4 0.14 11.6 0.2 1.7 2 0 0 2 2 2 0 Mediator of RNA polymerase II transcription complex subunit 8 Peptidase_C37 PF05416.7 KLO14551.1 - 8.3 4.5 12.7 1.8 6.7 0.3 2.1 2 0 0 2 2 2 0 Southampton virus-type processing peptidase DUF2435 PF10363.4 KLO14553.1 - 1.4e-27 95.4 1.3 4.6e-26 90.5 0.1 3.7 3 1 0 3 3 3 1 Protein of unknown function (DUF2435) DUF2411 PF10304.4 KLO14553.1 - 0.012 15.1 0.5 0.033 13.7 0.4 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF2411) HEAT PF02985.17 KLO14553.1 - 4.5 7.6 0.0 4.5 7.6 0.0 5.6 7 0 0 7 7 7 0 HEAT repeat Aldedh PF00171.17 KLO14554.1 - 1.9e-105 352.9 0.0 2.2e-105 352.6 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family BTB PF00651.26 KLO14555.1 - 3.6e-10 39.8 0.0 6.7e-10 38.9 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain Zn_Tnp_IS1595 PF12760.2 KLO14555.1 - 0.042 13.6 1.0 0.099 12.4 0.1 2.0 2 0 0 2 2 2 0 Transposase zinc-ribbon domain Hydrophobin PF01185.13 KLO14556.1 - 3.5e-23 81.8 10.8 4.3e-23 81.5 7.5 1.1 1 0 0 1 1 1 1 Fungal hydrophobin G0-G1_switch_2 PF15103.1 KLO14556.1 - 2.4 8.4 4.7 3.5 7.8 2.8 1.6 1 1 0 1 1 1 0 G0/G1 switch protein 2 Hydrophobin PF01185.13 KLO14557.1 - 7.6e-09 35.9 1.7 9.6e-09 35.5 1.2 1.1 1 0 0 1 1 1 1 Fungal hydrophobin Hydrophobin PF01185.13 KLO14558.1 - 6e-24 84.2 12.6 7.2e-24 84.0 8.7 1.1 1 0 0 1 1 1 1 Fungal hydrophobin Toxin_12 PF07740.7 KLO14558.1 - 2.6 8.5 9.3 7.3 7.1 0.6 2.4 2 0 0 2 2 2 0 Ion channel inhibitory toxin Hydrophobin PF01185.13 KLO14560.1 - 3.6e-22 78.5 9.3 4.4e-22 78.3 6.4 1.1 1 0 0 1 1 1 1 Fungal hydrophobin Hydrophobin PF01185.13 KLO14561.1 - 2.9e-10 40.4 9.6 3.9e-10 40.0 6.6 1.2 1 0 0 1 1 1 1 Fungal hydrophobin Hydrophobin PF01185.13 KLO14562.1 - 5.1e-23 81.3 11.7 6.9e-23 80.9 8.1 1.2 1 0 0 1 1 1 1 Fungal hydrophobin DUF2997 PF11211.3 KLO14562.1 - 0.43 10.0 2.9 5.6 6.4 0.1 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF2997) gpUL132 PF11359.3 KLO14562.1 - 0.64 9.3 4.6 0.83 8.9 3.2 1.1 1 0 0 1 1 1 0 Glycoprotein UL132 Toxin_29 PF08116.6 KLO14562.1 - 7 6.5 10.1 6 6.7 2.9 2.3 2 0 0 2 2 2 0 PhTx neurotoxin family Telomere_reg-2 PF10193.4 KLO14563.1 - 2e-29 102.1 0.0 4.7e-29 100.9 0.0 1.7 1 0 0 1 1 1 1 Telomere length regulation protein Methyltransf_16 PF10294.4 KLO14564.1 - 1.7e-14 53.6 0.0 2.2e-09 37.0 0.0 3.1 2 1 0 2 2 2 2 Putative methyltransferase Methyltransf_18 PF12847.2 KLO14564.1 - 0.0088 16.6 0.2 0.088 13.3 0.1 2.5 2 1 0 2 2 2 1 Methyltransferase domain MTS PF05175.9 KLO14564.1 - 0.039 13.3 0.1 0.32 10.3 0.0 2.1 1 1 1 2 2 2 0 Methyltransferase small domain Methyltransf_26 PF13659.1 KLO14564.1 - 0.069 13.1 0.0 0.19 11.7 0.0 1.7 2 0 0 2 2 2 0 Methyltransferase domain HA2 PF04408.18 KLO14565.1 - 1.9e-27 95.2 0.0 9.9e-27 92.9 0.0 2.3 2 0 0 2 2 2 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.11 KLO14565.1 - 2.2e-22 79.0 0.0 9.3e-22 77.0 0.0 2.0 2 0 0 2 2 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold DEAD PF00270.24 KLO14565.1 - 1.9e-07 30.7 0.3 8.1e-07 28.6 0.0 2.2 3 0 0 3 3 3 1 DEAD/DEAH box helicase AAA_22 PF13401.1 KLO14565.1 - 5.4e-06 26.5 0.1 1.5e-05 25.1 0.0 1.8 1 0 0 1 1 1 1 AAA domain Helicase_C PF00271.26 KLO14565.1 - 8.2e-05 22.3 0.0 0.00022 21.0 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain T2SE PF00437.15 KLO14565.1 - 0.0013 17.7 0.0 0.004 16.0 0.0 1.7 2 0 0 2 2 2 1 Type II/IV secretion system protein DUF2075 PF09848.4 KLO14565.1 - 0.0013 17.7 0.0 0.0025 16.8 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) ResIII PF04851.10 KLO14565.1 - 0.0032 17.3 0.0 2 8.1 0.0 2.6 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit AAA_14 PF13173.1 KLO14565.1 - 0.012 15.4 0.1 0.091 12.6 0.1 2.3 1 1 0 1 1 1 0 AAA domain Arch_ATPase PF01637.13 KLO14565.1 - 0.016 14.8 0.2 0.09 12.4 0.0 2.2 2 0 0 2 2 2 0 Archaeal ATPase KaiC PF06745.8 KLO14565.1 - 0.023 13.7 0.0 0.047 12.7 0.0 1.4 1 0 0 1 1 1 0 KaiC Flavi_DEAD PF07652.9 KLO14565.1 - 0.045 13.4 0.0 0.1 12.3 0.0 1.6 1 0 0 1 1 1 0 Flavivirus DEAD domain ABC_tran PF00005.22 KLO14565.1 - 0.047 13.9 0.1 0.21 11.8 0.0 2.1 2 0 0 2 2 2 0 ABC transporter NACHT PF05729.7 KLO14565.1 - 0.11 12.2 0.2 1 8.9 0.0 2.3 2 0 0 2 2 2 0 NACHT domain AAA_23 PF13476.1 KLO14565.1 - 0.19 12.0 0.8 0.41 10.9 0.0 2.0 1 1 0 1 1 1 0 AAA domain LRR_6 PF13516.1 KLO14566.1 - 2e-12 45.7 0.5 2.8 8.2 0.0 10.0 11 0 0 11 11 11 3 Leucine Rich repeat F-box-like PF12937.2 KLO14566.1 - 3.3e-11 42.7 4.0 8.9e-11 41.3 2.8 1.8 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.2 KLO14566.1 - 6.3e-11 41.6 1.3 3.5 7.3 0.0 7.0 4 3 4 8 8 8 6 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 KLO14566.1 - 7e-08 31.4 9.7 15 6.1 0.0 9.0 9 2 0 9 9 9 1 Leucine Rich Repeat LRR_8 PF13855.1 KLO14566.1 - 1.3e-07 31.2 8.1 0.13 12.0 0.0 6.0 3 2 4 7 7 7 3 Leucine rich repeat LRR_7 PF13504.1 KLO14566.1 - 0.068 13.3 13.7 69 4.3 0.0 8.0 10 0 0 10 10 10 0 Leucine rich repeat Ste50p-SAM PF09235.5 KLO14566.1 - 5.7 7.0 7.9 18 5.4 0.0 4.3 4 1 1 5 5 5 0 Ste50p, sterile alpha motif Shadoo PF14999.1 KLO14572.1 - 0.011 15.6 7.9 0.011 15.6 5.5 1.9 1 1 1 2 2 2 0 Shadow of prion protein, neuroprotective ETX_MTX2 PF03318.8 KLO14572.1 - 0.06 12.8 1.8 0.74 9.3 0.2 2.2 2 0 0 2 2 2 0 Clostridium epsilon toxin ETX/Bacillus mosquitocidal toxin MTX2 HnRNP_M PF11532.3 KLO14572.1 - 0.13 12.4 0.5 0.31 11.1 0.3 1.7 1 0 0 1 1 1 0 Heterogeneous nuclear ribonucleoprotein M Ribosomal_L37ae PF01780.14 KLO14573.1 - 4.4e-32 109.8 4.2 4.8e-32 109.6 2.9 1.0 1 0 0 1 1 1 1 Ribosomal L37ae protein family Zn_Tnp_IS1595 PF12760.2 KLO14573.1 - 0.0013 18.4 3.2 0.0019 17.9 2.2 1.3 1 0 0 1 1 1 1 Transposase zinc-ribbon domain zf-BED PF02892.10 KLO14573.1 - 0.0045 16.7 3.6 0.036 13.8 0.1 2.2 1 1 1 2 2 2 1 BED zinc finger zf-FCS PF06467.9 KLO14573.1 - 0.044 13.4 0.7 1.6 8.4 0.1 2.2 2 0 0 2 2 2 0 MYM-type Zinc finger with FCS sequence motif NST1 PF13945.1 KLO14573.1 - 0.071 13.1 0.8 0.093 12.7 0.5 1.1 1 0 0 1 1 1 0 Salt tolerance down-regulator A2L_zn_ribbon PF08792.5 KLO14573.1 - 0.085 12.3 4.7 0.34 10.4 0.1 2.1 2 0 0 2 2 2 0 A2L zinc ribbon domain C1_1 PF00130.17 KLO14573.1 - 0.095 12.4 2.8 0.14 11.9 2.0 1.3 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) OrfB_Zn_ribbon PF07282.6 KLO14573.1 - 0.095 12.3 1.2 0.13 11.9 0.8 1.3 1 0 0 1 1 1 0 Putative transposase DNA-binding domain Zn-ribbon_8 PF09723.5 KLO14573.1 - 0.096 12.6 1.6 0.89 9.5 0.1 2.2 2 0 0 2 2 2 0 Zinc ribbon domain NOB1_Zn_bind PF08772.6 KLO14573.1 - 0.34 10.7 3.2 1.3 8.9 0.1 2.2 1 1 1 2 2 2 0 Nin one binding (NOB1) Zn-ribbon like Elf1 PF05129.8 KLO14573.1 - 0.4 10.3 3.9 0.76 9.5 2.7 1.5 1 1 0 1 1 1 0 Transcription elongation factor Elf1 like Ribosomal_L44 PF00935.14 KLO14573.1 - 1.7 8.7 6.9 1.1 9.2 0.6 2.2 1 1 1 2 2 2 0 Ribosomal protein L44 zf-H2C2_2 PF13465.1 KLO14573.1 - 2.5 8.5 6.4 2.6 8.5 0.3 2.2 1 1 1 2 2 2 0 Zinc-finger double domain Enterotoxin_b PF01376.13 KLO14574.1 - 0.041 13.7 0.1 0.14 12.0 0.0 1.9 2 0 0 2 2 2 0 Heat-labile enterotoxin beta chain gerPA PF10676.4 KLO14574.1 - 0.059 13.2 0.3 0.14 12.0 0.2 1.6 1 0 0 1 1 1 0 Spore germination protein gerPA/gerPF ABC_tran PF00005.22 KLO14578.1 - 4.3e-35 120.9 0.0 9.6e-35 119.8 0.0 1.6 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.18 KLO14578.1 - 1.1e-19 70.8 8.4 2e-19 70.0 5.8 1.4 1 0 0 1 1 1 1 ABC transporter transmembrane region AAA_21 PF13304.1 KLO14578.1 - 5.9e-08 33.0 0.0 0.0013 18.7 0.0 2.4 1 1 1 2 2 2 2 AAA domain AAA_16 PF13191.1 KLO14578.1 - 1.6e-06 28.2 0.1 1.6e-06 28.2 0.1 2.0 2 0 0 2 2 2 1 AAA ATPase domain SMC_N PF02463.14 KLO14578.1 - 5e-06 25.9 0.5 5.4e-05 22.5 0.3 2.1 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 KLO14578.1 - 0.00052 19.4 0.2 0.0012 18.2 0.1 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_22 PF13401.1 KLO14578.1 - 0.00071 19.7 0.1 0.0039 17.3 0.0 2.2 1 1 0 1 1 1 1 AAA domain DUF258 PF03193.11 KLO14578.1 - 0.0057 15.8 0.0 0.041 13.0 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_18 PF13238.1 KLO14578.1 - 0.023 15.0 0.0 0.15 12.3 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.1 KLO14578.1 - 0.046 14.5 0.0 0.12 13.1 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA PF00004.24 KLO14578.1 - 0.051 13.7 0.0 0.48 10.6 0.0 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) FtsK_SpoIIIE PF01580.13 KLO14578.1 - 0.089 12.2 0.0 0.2 11.0 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family MobB PF03205.9 KLO14578.1 - 0.12 12.0 0.2 1.1 8.9 0.0 2.4 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B SbcCD_C PF13558.1 KLO14578.1 - 0.19 11.6 1.3 0.97 9.3 0.1 2.7 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit PAT1 PF09770.4 KLO14578.1 - 9.2 4.3 14.2 15 3.6 9.8 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 RRM_1 PF00076.17 KLO14579.1 - 2.3e-12 46.3 0.0 2.7e-12 46.1 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KLO14579.1 - 1.4e-08 34.5 0.0 1.8e-08 34.2 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KLO14579.1 - 1.7e-08 34.1 0.0 2.1e-08 33.8 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Glyco_hydro_71 PF03659.9 KLO14581.1 - 6.3e-101 337.6 9.1 7.8e-101 337.3 6.3 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 71 Glyco_hydro_71 PF03659.9 KLO14582.1 - 3.1e-101 338.6 8.0 3.6e-101 338.4 5.5 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 71 NAD_kinase PF01513.16 KLO14583.1 - 4e-68 229.2 0.0 7.1e-68 228.4 0.0 1.3 1 0 0 1 1 1 1 ATP-NAD kinase DUF3435 PF11917.3 KLO14583.1 - 0.03 13.0 0.0 0.056 12.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3435) Spt5_N PF11942.3 KLO14583.1 - 0.19 12.3 11.8 2.4 8.8 7.0 2.8 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal PAXIP1_C PF15364.1 KLO14583.1 - 0.31 10.9 10.4 0.68 9.8 4.4 2.8 2 0 0 2 2 2 0 PAXIP1-associated-protein-1 C term PTIP binding protein Fer2_BFD PF04324.10 KLO14584.1 - 0.00036 20.5 0.3 0.0011 18.9 0.1 1.8 2 0 0 2 2 2 1 BFD-like [2Fe-2S] binding domain 2OG-FeII_Oxy PF03171.15 KLO14584.1 - 0.0012 19.1 0.1 0.006 16.8 0.0 2.2 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_3 PF13640.1 KLO14584.1 - 0.0051 17.3 0.1 0.022 15.2 0.0 2.1 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily Phage_Treg PF04761.7 KLO14584.1 - 0.056 13.2 0.1 0.33 10.7 0.0 2.2 2 0 0 2 2 2 0 Lactococcus bacteriophage putative transcription regulator ARL6IP6 PF15062.1 KLO14586.1 - 0.13 12.1 0.6 0.24 11.3 0.4 1.3 1 0 0 1 1 1 0 Haemopoietic lineage transmembrane helix DAP10 PF07213.6 KLO14589.1 - 0.014 15.1 0.5 0.036 13.8 0.3 1.7 1 0 0 1 1 1 0 DAP10 membrane protein TATR PF03430.8 KLO14589.1 - 0.22 10.0 1.7 0.26 9.8 1.1 1.0 1 0 0 1 1 1 0 Trans-activating transcriptional regulator IncA PF04156.9 KLO14589.1 - 1.4 8.5 8.6 0.2 11.2 0.4 2.2 2 0 0 2 2 2 0 IncA protein Presenilin PF01080.12 KLO14589.1 - 3.5 6.3 5.1 3 6.5 2.6 1.6 2 0 0 2 2 2 0 Presenilin Mito_carr PF00153.22 KLO14590.1 - 3e-72 238.4 0.1 4.1e-26 90.5 0.0 3.9 3 1 0 3 3 3 3 Mitochondrial carrier protein RhoGAP PF00620.22 KLO14591.1 - 5.9e-34 116.8 0.0 1.3e-33 115.7 0.0 1.6 1 0 0 1 1 1 1 RhoGAP domain DUF3533 PF12051.3 KLO14592.1 - 3.5e-100 335.4 16.3 4.4e-100 335.0 11.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3533) ABC2_membrane_3 PF12698.2 KLO14592.1 - 2.4e-10 40.0 21.9 3.5e-10 39.4 15.2 1.2 1 0 0 1 1 1 1 ABC-2 family transporter protein Syndecan PF01034.15 KLO14593.1 - 0.0036 16.9 0.1 0.0086 15.7 0.0 1.6 1 0 0 1 1 1 1 Syndecan domain TIP39 PF14980.1 KLO14593.1 - 0.0084 15.7 1.3 0.015 14.9 0.9 1.3 1 0 0 1 1 1 1 TIP39 peptide Adeno_E3_CR2 PF02439.10 KLO14593.1 - 0.073 12.6 1.0 0.14 11.6 0.7 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 EphA2_TM PF14575.1 KLO14593.1 - 0.076 13.4 0.1 3.4 8.1 0.0 2.4 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Herpes_gE PF02480.11 KLO14593.1 - 0.13 10.4 0.8 0.34 9.1 0.0 1.9 2 0 0 2 2 2 0 Alphaherpesvirus glycoprotein E TMEM51 PF15345.1 KLO14593.1 - 1 9.0 4.8 0.57 9.8 0.0 2.7 3 0 0 3 3 3 0 Transmembrane protein 51 TP6A_N PF04406.9 KLO14594.1 - 2.5e-21 75.0 0.0 4.8e-21 74.1 0.0 1.4 1 0 0 1 1 1 1 Type IIB DNA topoisomerase GTP_EFTU PF00009.22 KLO14595.1 - 1.8e-21 76.4 0.0 3.4e-21 75.5 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 KLO14595.1 - 4.9e-17 61.9 0.0 1.2e-16 60.7 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 KLO14595.1 - 0.0045 17.0 0.1 0.043 13.9 0.0 2.7 2 0 0 2 2 2 1 Elongation factor Tu domain 2 PduV-EutP PF10662.4 KLO14595.1 - 0.016 14.7 0.5 0.96 8.9 0.1 3.0 2 1 1 3 3 3 0 Ethanolamine utilisation - propanediol utilisation MobB PF03205.9 KLO14595.1 - 0.067 12.8 0.1 0.15 11.7 0.1 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B UDPG_MGDP_dh_N PF03721.9 KLO14595.1 - 0.077 12.3 0.0 11 5.3 0.0 2.4 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain MMR_HSR1 PF01926.18 KLO14595.1 - 0.096 12.6 0.1 0.23 11.4 0.0 1.8 1 1 0 1 1 1 0 50S ribosome-binding GTPase Miro PF08477.8 KLO14595.1 - 0.29 11.6 0.9 5.4 7.5 0.0 2.6 2 1 0 2 2 2 0 Miro-like protein Glyco_hydro_18 PF00704.23 KLO14596.1 - 4.1e-93 312.5 0.5 4.8e-93 312.3 0.4 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 ABC_tran PF00005.22 KLO14597.1 - 5.1e-47 159.6 0.0 1.8e-28 99.5 0.0 4.0 2 2 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 KLO14597.1 - 4e-13 49.9 0.7 0.0052 16.7 0.0 4.1 4 0 0 4 4 4 3 AAA domain SMC_N PF02463.14 KLO14597.1 - 4.8e-11 42.2 0.0 0.00014 21.1 0.0 4.1 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain Chromo PF00385.19 KLO14597.1 - 4.4e-10 39.0 0.5 8.3e-10 38.1 0.4 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain AAA_17 PF13207.1 KLO14597.1 - 1.3e-07 32.4 0.0 0.024 15.4 0.0 2.9 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.1 KLO14597.1 - 1.4e-07 31.6 0.1 0.0013 18.8 0.0 3.7 3 0 0 3 3 3 1 AAA domain NACHT PF05729.7 KLO14597.1 - 4.8e-07 29.5 1.3 0.00021 20.9 0.0 3.5 4 0 0 4 4 4 1 NACHT domain Miro PF08477.8 KLO14597.1 - 1.4e-06 28.7 0.0 0.014 15.9 0.0 3.3 3 0 0 3 3 2 2 Miro-like protein AAA_16 PF13191.1 KLO14597.1 - 1.4e-06 28.4 3.8 0.29 11.0 0.1 4.8 4 2 0 4 4 3 2 AAA ATPase domain AAA_29 PF13555.1 KLO14597.1 - 1.5e-06 27.6 1.3 0.043 13.3 0.1 3.3 3 0 0 3 3 2 2 P-loop containing region of AAA domain AAA_23 PF13476.1 KLO14597.1 - 2.1e-06 28.2 2.8 0.023 15.0 0.4 2.7 2 1 0 2 2 2 2 AAA domain MMR_HSR1 PF01926.18 KLO14597.1 - 2.3e-06 27.5 0.0 0.018 14.9 0.0 3.0 2 0 0 2 2 2 2 50S ribosome-binding GTPase DUF258 PF03193.11 KLO14597.1 - 1.5e-05 24.2 0.0 0.019 14.1 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_28 PF13521.1 KLO14597.1 - 2e-05 24.5 0.0 0.1 12.5 0.0 2.7 2 0 0 2 2 2 2 AAA domain MobB PF03205.9 KLO14597.1 - 2.5e-05 24.0 0.0 0.2 11.3 0.0 2.7 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B AAA_14 PF13173.1 KLO14597.1 - 3.6e-05 23.6 0.5 0.28 11.0 0.1 3.6 2 1 0 2 2 2 1 AAA domain AAA_18 PF13238.1 KLO14597.1 - 6.3e-05 23.2 0.2 0.52 10.6 0.0 3.1 4 0 0 4 4 2 2 AAA domain AAA_33 PF13671.1 KLO14597.1 - 0.00012 21.9 0.0 0.45 10.3 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA PF00004.24 KLO14597.1 - 0.00021 21.5 0.0 0.6 10.3 0.0 3.4 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_10 PF12846.2 KLO14597.1 - 0.00023 20.7 0.5 0.67 9.3 0.1 2.9 2 0 0 2 2 2 2 AAA-like domain AAA_5 PF07728.9 KLO14597.1 - 0.00032 20.4 1.3 8.8 6.0 0.0 4.2 4 0 0 4 4 3 0 AAA domain (dynein-related subfamily) AAA_13 PF13166.1 KLO14597.1 - 0.0006 18.4 0.2 0.41 9.0 0.0 2.9 3 0 0 3 3 3 1 AAA domain Zeta_toxin PF06414.7 KLO14597.1 - 0.00065 18.8 0.2 1.3 8.0 0.1 3.3 3 0 0 3 3 3 1 Zeta toxin PduV-EutP PF10662.4 KLO14597.1 - 0.00088 18.7 1.0 1.4 8.3 0.0 3.3 4 0 0 4 4 4 1 Ethanolamine utilisation - propanediol utilisation DUF87 PF01935.12 KLO14597.1 - 0.001 18.9 2.1 1.6 8.4 0.1 3.9 5 0 0 5 5 4 1 Domain of unknown function DUF87 RNA_helicase PF00910.17 KLO14597.1 - 0.0011 19.1 0.1 2 8.6 0.0 2.9 2 0 0 2 2 2 1 RNA helicase Arch_ATPase PF01637.13 KLO14597.1 - 0.0013 18.4 0.2 0.52 9.9 0.0 3.2 3 0 0 3 3 3 1 Archaeal ATPase ArgK PF03308.11 KLO14597.1 - 0.0019 17.0 0.4 0.081 11.6 0.0 2.4 2 0 0 2 2 2 1 ArgK protein cobW PF02492.14 KLO14597.1 - 0.002 17.6 0.4 0.99 8.8 0.0 2.8 3 0 0 3 3 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_30 PF13604.1 KLO14597.1 - 0.0022 17.6 0.1 3.3 7.2 0.0 3.6 4 0 0 4 4 2 0 AAA domain AAA_24 PF13479.1 KLO14597.1 - 0.0034 16.9 1.1 1.1 8.8 0.0 2.8 3 0 0 3 3 2 1 AAA domain KAP_NTPase PF07693.9 KLO14597.1 - 0.004 16.2 0.2 0.3 10.0 0.0 3.0 3 0 0 3 3 3 1 KAP family P-loop domain AAA_25 PF13481.1 KLO14597.1 - 0.0042 16.5 0.3 8.1 5.7 0.0 3.5 3 0 0 3 3 3 0 AAA domain SRPRB PF09439.5 KLO14597.1 - 0.006 15.8 0.0 0.67 9.1 0.0 2.5 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit HEAT PF02985.17 KLO14597.1 - 0.0074 16.2 3.0 7.6 6.9 0.0 4.4 4 0 0 4 4 3 0 HEAT repeat ATP_bind_1 PF03029.12 KLO14597.1 - 0.0079 15.7 0.1 2.2 7.7 0.0 2.5 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein CLASP_N PF12348.3 KLO14597.1 - 0.01 15.2 0.1 4.5 6.5 0.1 2.5 2 0 0 2 2 2 0 CLASP N terminal Arf PF00025.16 KLO14597.1 - 0.012 14.9 0.0 0.64 9.2 0.0 2.4 2 0 0 2 2 2 0 ADP-ribosylation factor family AAA_15 PF13175.1 KLO14597.1 - 0.025 13.6 0.0 4.6 6.1 0.0 2.4 2 0 0 2 2 2 0 AAA ATPase domain NB-ARC PF00931.17 KLO14597.1 - 0.032 13.0 0.2 4.8 5.9 0.0 2.4 2 0 0 2 2 2 0 NB-ARC domain DUF3584 PF12128.3 KLO14597.1 - 0.034 11.5 1.6 2.4 5.3 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) Thymidylate_kin PF02223.12 KLO14597.1 - 0.04 13.2 0.0 5.6 6.3 0.0 2.5 2 0 0 2 2 2 0 Thymidylate kinase ATP-synt_ab PF00006.20 KLO14597.1 - 0.051 13.0 0.0 1.5 8.2 0.0 2.5 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain NTPase_1 PF03266.10 KLO14597.1 - 0.056 13.1 0.2 12 5.6 0.2 2.8 2 0 0 2 2 2 0 NTPase Dynamin_N PF00350.18 KLO14597.1 - 0.063 13.0 0.3 0.36 10.6 0.0 2.4 3 0 0 3 3 2 0 Dynamin family FtsK_SpoIIIE PF01580.13 KLO14597.1 - 0.086 12.3 0.4 5.8 6.3 0.0 3.1 3 0 0 3 3 3 0 FtsK/SpoIIIE family Sigma54_activ_2 PF14532.1 KLO14597.1 - 0.11 12.5 0.0 4.1 7.4 0.0 2.7 2 0 0 2 2 2 0 Sigma-54 interaction domain Adaptin_N PF01602.15 KLO14597.1 - 0.11 10.8 1.4 7 4.8 0.8 2.1 1 1 0 1 1 1 0 Adaptin N terminal region PRK PF00485.13 KLO14597.1 - 0.13 11.8 0.0 6.1 6.3 0.0 2.7 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family MutS_V PF00488.16 KLO14597.1 - 0.14 11.5 0.4 17 4.7 0.0 2.5 2 0 0 2 2 2 0 MutS domain V HEAT_EZ PF13513.1 KLO14597.1 - 1.2 9.7 7.6 12 6.5 0.1 4.8 4 1 1 5 5 4 0 HEAT-like repeat Homeobox PF00046.24 KLO14598.1 - 4.9e-16 58.1 3.4 9.1e-16 57.2 2.3 1.5 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 KLO14598.1 - 0.018 14.7 0.1 0.018 14.7 0.1 3.5 4 0 0 4 4 4 0 Homeobox KN domain Homez PF11569.3 KLO14598.1 - 0.15 11.1 0.1 0.36 9.9 0.1 1.7 1 0 0 1 1 1 0 Homeodomain leucine-zipper encoding, Homez Pkinase PF00069.20 KLO14599.1 - 5.3e-56 189.6 0.1 1.1e-37 129.5 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 KLO14599.1 - 7.6e-24 84.1 0.1 4.2e-16 58.7 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 KLO14599.1 - 3.5e-06 26.2 0.1 0.00036 19.5 0.0 2.7 3 0 0 3 3 3 1 Kinase-like Pkinase_C PF00433.19 KLO14599.1 - 0.0028 18.1 0.0 0.0077 16.7 0.0 1.8 1 0 0 1 1 1 1 Protein kinase C terminal domain APH PF01636.18 KLO14599.1 - 0.021 14.5 2.6 0.024 14.4 0.3 2.2 2 0 0 2 2 2 0 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.6 KLO14599.1 - 0.039 12.7 0.4 0.059 12.1 0.3 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Seadorna_VP7 PF07387.6 KLO14599.1 - 0.14 10.9 0.0 0.21 10.3 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 zf-C2H2 PF00096.21 KLO14600.1 - 4.3e-14 51.8 8.6 8.9e-08 32.0 1.0 2.1 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 KLO14600.1 - 1.4e-09 37.7 13.1 2.1e-07 30.8 0.1 3.0 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 KLO14600.1 - 3.9e-09 36.1 8.2 3.1e-05 24.0 1.1 2.1 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 KLO14600.1 - 5.5e-07 29.5 3.8 5.2e-06 26.4 0.4 2.4 3 0 0 3 3 3 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 KLO14600.1 - 4.4e-05 23.5 2.2 0.00017 21.6 0.4 2.2 2 0 0 2 2 2 1 Zinc-finger of C2H2 type Zn-ribbon_8 PF09723.5 KLO14600.1 - 0.0018 18.1 2.8 0.38 10.7 0.3 2.1 2 0 0 2 2 2 2 Zinc ribbon domain zf-TRAF PF02176.13 KLO14600.1 - 0.0022 18.3 1.4 0.0026 18.0 0.9 1.2 1 0 0 1 1 1 1 TRAF-type zinc finger zf-C2H2_6 PF13912.1 KLO14600.1 - 0.0033 17.2 5.7 0.023 14.6 0.4 2.5 2 1 0 2 2 2 1 C2H2-type zinc finger CCAP PF11105.3 KLO14600.1 - 0.0095 15.6 0.9 0.0095 15.6 0.6 1.1 1 0 0 1 1 1 1 Arthropod cardioacceleratory peptide 2a zf-C2HC_2 PF13913.1 KLO14600.1 - 0.027 14.1 7.5 0.065 12.9 0.4 2.4 2 1 0 2 2 2 0 zinc-finger of a C2HC-type zf-C2H2_2 PF12756.2 KLO14600.1 - 0.029 14.4 1.2 0.11 12.6 0.1 1.9 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-Di19 PF05605.7 KLO14600.1 - 0.12 12.5 1.4 0.21 11.7 1.0 1.5 1 1 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf-BED PF02892.10 KLO14600.1 - 0.2 11.4 5.0 0.52 10.1 0.7 2.2 1 1 1 2 2 2 0 BED zinc finger zf-CHCC PF10276.4 KLO14600.1 - 0.24 11.2 4.5 5.2 7.0 1.5 2.2 2 0 0 2 2 2 0 Zinc-finger domain zf-H2C2_5 PF13909.1 KLO14600.1 - 7.8 6.9 10.1 1.8 8.9 0.7 2.8 2 1 0 2 2 2 0 C2H2-type zinc-finger domain DUF1272 PF06906.6 KLO14600.1 - 8.5 6.3 9.0 2.2 8.1 1.0 2.2 1 1 0 2 2 2 0 Protein of unknown function (DUF1272) BolA PF01722.13 KLO14602.1 - 3.7e-28 97.2 0.4 4.6e-28 97.0 0.3 1.1 1 0 0 1 1 1 1 BolA-like protein Pyrid_oxidase_2 PF13883.1 KLO14605.1 - 1.3e-27 96.6 0.0 1.7e-27 96.2 0.0 1.2 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Poly_export PF02563.11 KLO14605.1 - 0.12 12.2 0.0 0.19 11.5 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis/export protein DNA_ligase_A_M PF01068.16 KLO14606.1 - 3.6e-39 134.2 0.1 6.4e-37 126.8 0.0 2.5 2 0 0 2 2 2 2 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.9 KLO14606.1 - 3e-38 131.4 0.0 5.2e-38 130.6 0.0 1.4 1 0 0 1 1 1 1 DNA ligase N terminus DNA_ligase_A_C PF04679.10 KLO14606.1 - 1.1e-18 67.4 0.0 3.3e-18 65.8 0.0 1.9 1 0 0 1 1 1 1 ATP dependent DNA ligase C terminal region zf-H2C2_2 PF13465.1 KLO14607.1 - 2.9e-09 36.7 2.1 1.7e-05 24.8 1.1 3.3 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 KLO14607.1 - 2.6e-07 30.5 7.1 0.0003 20.9 0.2 3.2 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2 PF00096.21 KLO14607.1 - 3e-05 24.1 10.5 0.0014 18.8 1.9 3.3 3 1 1 4 4 4 2 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.3 KLO14607.1 - 0.0062 16.6 5.0 0.059 13.5 0.6 2.9 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 KLO14607.1 - 0.099 12.8 0.1 0.099 12.8 0.0 3.8 4 0 0 4 4 4 0 Zinc-finger of C2H2 type PAT1 PF09770.4 KLO14607.1 - 1.6 6.8 13.5 1.9 6.6 9.4 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Acetyltransf_1 PF00583.19 KLO14608.1 - 5.5e-15 55.1 0.0 7.8e-15 54.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 KLO14608.1 - 1.1e-07 31.9 0.0 3.4e-07 30.3 0.0 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 KLO14608.1 - 8e-06 25.8 0.0 1.1e-05 25.4 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 KLO14608.1 - 1.6e-05 24.9 0.0 2e-05 24.5 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 KLO14608.1 - 0.0011 19.0 0.0 0.0016 18.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 KLO14608.1 - 0.0062 16.6 0.0 0.0081 16.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 KLO14608.1 - 0.02 14.6 0.0 0.03 14.0 0.0 1.4 1 0 0 1 1 1 0 FR47-like protein Pkinase PF00069.20 KLO14610.1 - 2.4e-60 203.9 0.0 3.3e-60 203.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KLO14610.1 - 4.1e-37 127.6 0.0 5.5e-37 127.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KLO14610.1 - 5.1e-07 28.9 0.0 1.2e-06 27.6 0.0 1.6 2 1 0 2 2 2 1 Kinase-like APH PF01636.18 KLO14610.1 - 0.16 11.6 0.0 0.36 10.5 0.0 1.5 1 1 0 1 1 1 0 Phosphotransferase enzyme family IU_nuc_hydro PF01156.14 KLO14611.1 - 9.4e-54 182.7 0.0 1.2e-53 182.3 0.0 1.1 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase ATP_transf PF09830.4 KLO14613.1 - 3.5e-20 71.5 0.0 5.8e-20 70.8 0.0 1.4 1 0 0 1 1 1 1 ATP adenylyltransferase HIT PF01230.18 KLO14613.1 - 0.0059 17.1 0.0 0.074 13.6 0.0 2.4 2 1 0 2 2 2 1 HIT domain YcfA PF07927.7 KLO14615.1 - 0.011 15.6 0.0 0.035 14.0 0.0 1.9 1 0 0 1 1 1 0 YcfA-like protein CDC45 PF02724.9 KLO14615.1 - 5.9 4.8 17.4 6.9 4.5 7.3 2.2 2 0 0 2 2 2 0 CDC45-like protein Ran_BP1 PF00638.13 KLO14616.1 - 6.7e-15 55.2 0.3 1.5e-14 54.0 0.2 1.6 2 0 0 2 2 2 1 RanBP1 domain NUP50 PF08911.6 KLO14616.1 - 1.8e-11 44.2 0.1 1.8e-11 44.2 0.0 4.3 6 0 0 6 6 6 1 NUP50 (Nucleoporin 50 kDa) WH1 PF00568.18 KLO14616.1 - 0.028 14.1 0.0 0.049 13.3 0.0 1.4 1 0 0 1 1 1 0 WH1 domain RabGAP-TBC PF00566.13 KLO14617.1 - 3.2e-50 170.5 0.2 5.3e-50 169.8 0.1 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain GAF PF01590.21 KLO14617.1 - 0.062 13.4 0.3 14 5.7 0.0 2.7 3 0 0 3 3 3 0 GAF domain IL34 PF15036.1 KLO14617.1 - 0.12 11.9 0.0 0.21 11.1 0.0 1.3 1 0 0 1 1 1 0 Interleukin 34 Cullin_binding PF03556.10 KLO14617.1 - 0.2 11.7 1.8 0.25 11.4 0.4 1.8 2 0 0 2 2 2 0 Cullin binding Ank PF00023.25 KLO14619.1 - 7.3e-12 44.4 0.4 0.00019 21.0 0.2 2.6 2 0 0 2 2 2 2 Ankyrin repeat Ank_2 PF12796.2 KLO14619.1 - 1.6e-11 44.3 0.1 3.1e-11 43.4 0.1 1.4 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) TIG PF01833.19 KLO14619.1 - 1.2e-10 41.2 0.3 4e-10 39.5 0.2 2.0 2 0 0 2 2 2 1 IPT/TIG domain Ank_5 PF13857.1 KLO14619.1 - 1.3e-09 37.9 0.7 2e-07 31.0 0.0 2.6 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 KLO14619.1 - 2.5e-06 27.1 0.2 0.037 14.2 0.0 2.7 2 0 0 2 2 2 2 Ankyrin repeat Ank_4 PF13637.1 KLO14619.1 - 5.4e-05 23.5 0.2 0.00027 21.3 0.1 2.3 1 1 1 2 2 2 1 Ankyrin repeats (many copies) AAA_12 PF13087.1 KLO14620.1 - 1.8e-33 115.6 0.0 3.1e-33 114.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 KLO14620.1 - 1.6e-29 103.1 0.0 2.5e-28 99.2 0.0 2.5 2 1 0 2 2 2 1 AAA domain AAA_19 PF13245.1 KLO14620.1 - 3.7e-08 33.0 0.2 1.6e-07 30.9 0.1 2.1 1 0 0 1 1 1 1 Part of AAA domain AAA_30 PF13604.1 KLO14620.1 - 2.9e-07 30.2 0.4 7e-05 22.4 0.0 2.8 3 0 0 3 3 3 1 AAA domain DUF2075 PF09848.4 KLO14620.1 - 0.0021 17.0 0.0 0.0053 15.7 0.0 1.7 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) UvrD-helicase PF00580.16 KLO14620.1 - 0.042 13.1 0.0 0.19 10.9 0.0 2.1 2 0 0 2 2 2 0 UvrD/REP helicase N-terminal domain KaiC PF06745.8 KLO14620.1 - 0.058 12.5 0.0 0.11 11.5 0.0 1.4 1 0 0 1 1 1 0 KaiC UvrD_C_2 PF13538.1 KLO14620.1 - 0.07 13.2 0.0 0.19 11.8 0.0 1.8 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain ResIII PF04851.10 KLO14620.1 - 0.077 12.8 0.0 0.22 11.3 0.0 1.7 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit ETF_alpha PF00766.14 KLO14621.1 - 2.5e-35 119.9 1.2 3.9e-35 119.3 0.2 1.8 2 0 0 2 2 2 1 Electron transfer flavoprotein FAD-binding domain ETF PF01012.16 KLO14621.1 - 3.1e-33 114.8 0.6 6e-33 113.8 0.4 1.5 1 0 0 1 1 1 1 Electron transfer flavoprotein domain TPR_11 PF13414.1 KLO14622.1 - 6e-21 73.8 7.1 6e-11 41.8 0.1 3.2 2 1 2 4 4 4 3 TPR repeat TPR_1 PF00515.23 KLO14622.1 - 7.9e-16 56.9 0.3 0.00027 20.4 0.0 3.8 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.12 KLO14622.1 - 2.6e-14 51.9 3.7 0.0013 18.5 0.1 5.0 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_16 PF13432.1 KLO14622.1 - 3.3e-12 46.7 0.8 7e-08 32.9 0.0 4.2 2 1 2 4 4 4 3 Tetratricopeptide repeat TPR_17 PF13431.1 KLO14622.1 - 9e-09 34.8 0.2 0.014 15.5 0.0 4.3 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_7 PF13176.1 KLO14622.1 - 7.8e-08 31.5 0.0 0.36 10.7 0.0 4.3 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_12 PF13424.1 KLO14622.1 - 1.6e-07 31.1 7.0 0.0035 17.2 0.0 3.5 2 2 1 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.1 KLO14622.1 - 1.2e-06 27.8 0.1 0.24 11.2 0.0 4.4 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.1 KLO14622.1 - 1.8e-06 28.0 16.1 0.016 15.8 0.0 6.6 2 2 4 6 6 6 2 Tetratricopeptide repeat TPR_19 PF14559.1 KLO14622.1 - 0.00014 22.1 10.2 0.11 12.8 0.1 4.4 3 2 1 4 4 4 2 Tetratricopeptide repeat TPR_10 PF13374.1 KLO14622.1 - 0.0018 18.1 8.4 0.13 12.2 0.1 4.8 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_15 PF13429.1 KLO14622.1 - 0.0077 15.3 1.7 0.43 9.6 0.1 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_9 PF13371.1 KLO14622.1 - 0.034 14.0 0.1 4.7 7.1 0.0 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat Coatomer_E PF04733.9 KLO14622.1 - 0.053 12.7 0.0 0.14 11.3 0.0 1.7 1 0 0 1 1 1 0 Coatomer epsilon subunit Apc3 PF12895.2 KLO14622.1 - 0.074 13.1 0.1 0.72 10.0 0.0 2.5 2 1 1 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_20 PF14561.1 KLO14622.1 - 0.18 11.9 2.0 1.7 8.8 0.0 3.6 2 2 3 5 5 5 0 Tetratricopeptide repeat DUF4066 PF13278.1 KLO14623.1 - 3.4e-28 98.0 0.0 4.1e-28 97.7 0.0 1.1 1 0 0 1 1 1 1 Putative amidotransferase DJ-1_PfpI PF01965.19 KLO14623.1 - 6.3e-16 58.1 0.0 8.3e-16 57.7 0.0 1.1 1 0 0 1 1 1 1 DJ-1/PfpI family GATase PF00117.23 KLO14623.1 - 0.083 12.3 0.0 0.13 11.7 0.0 1.6 1 1 0 1 1 1 0 Glutamine amidotransferase class-I DUF4066 PF13278.1 KLO14624.1 - 2.5e-27 95.1 0.0 4.5e-27 94.3 0.0 1.4 1 1 0 1 1 1 1 Putative amidotransferase DJ-1_PfpI PF01965.19 KLO14624.1 - 4.2e-17 61.9 0.0 5.2e-17 61.6 0.0 1.2 1 0 0 1 1 1 1 DJ-1/PfpI family Oxidored_q6 PF01058.17 KLO14624.1 - 0.002 17.7 0.0 0.0066 16.0 0.0 1.7 1 1 0 2 2 2 1 NADH ubiquinone oxidoreductase, 20 Kd subunit DUF2819 PF10995.3 KLO14624.1 - 0.13 10.9 0.0 2.4 6.8 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2819) DUF3421 PF11901.3 KLO14626.1 - 0.006 16.3 0.0 0.013 15.1 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3421) Rifin_STEVOR PF02009.11 KLO14626.1 - 0.085 12.4 0.4 0.18 11.3 0.0 1.6 2 0 0 2 2 2 0 Rifin/stevor family Imm_superinfect PF14373.1 KLO14626.1 - 0.095 12.3 0.5 0.2 11.2 0.4 1.6 1 0 0 1 1 1 0 Superinfection immunity protein EphA2_TM PF14575.1 KLO14626.1 - 0.1 12.9 0.7 0.5 10.7 0.0 2.4 2 1 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Herpes_gE PF02480.11 KLO14626.1 - 0.13 10.4 0.0 0.13 10.4 0.0 1.7 2 0 0 2 2 2 0 Alphaherpesvirus glycoprotein E DUF4381 PF14316.1 KLO14626.1 - 0.13 12.3 0.0 0.26 11.3 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) ILVD_EDD PF00920.16 KLO14627.1 - 3.2e-194 646.1 0.0 3.8e-194 645.9 0.0 1.0 1 0 0 1 1 1 1 Dehydratase family FAD_binding_3 PF01494.14 KLO14628.1 - 3e-19 69.2 0.1 2.3e-17 63.0 0.0 2.8 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 KLO14628.1 - 4e-05 23.5 0.2 0.00013 21.9 0.1 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 KLO14628.1 - 0.00048 19.1 1.4 0.00054 18.9 0.2 1.6 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 KLO14628.1 - 0.014 15.7 0.3 0.037 14.4 0.2 1.7 1 1 1 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 KLO14628.1 - 0.015 13.9 0.2 0.59 8.6 0.1 2.1 1 1 1 2 2 2 0 Tryptophan halogenase NAD_binding_9 PF13454.1 KLO14628.1 - 0.1 12.3 0.0 0.33 10.6 0.0 1.8 2 0 0 2 2 2 0 FAD-NAD(P)-binding DUF262 PF03235.9 KLO14629.1 - 1.9e-17 64.0 0.4 6e-17 62.3 0.3 2.1 1 1 0 1 1 1 1 Protein of unknown function DUF262 DUF2036 PF09724.4 KLO14630.1 - 3.1e-55 187.6 0.3 3.8e-55 187.3 0.2 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2036) Zn_clus PF00172.13 KLO14632.1 - 1.3e-08 34.6 9.5 1.9e-08 34.0 6.6 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Cyclin PF08613.6 KLO14634.1 - 2.7e-09 37.5 0.0 3.1e-06 27.6 0.0 2.6 2 0 0 2 2 2 2 Cyclin CENP-T PF15511.1 KLO14634.1 - 0.011 15.0 0.7 0.011 15.0 0.5 2.6 3 0 0 3 3 3 0 Centromere kinetochore component CENP-T Cyclin_N PF00134.18 KLO14634.1 - 0.046 13.2 0.0 0.078 12.5 0.0 1.3 1 0 0 1 1 1 0 Cyclin, N-terminal domain Zn_Tnp_IS91 PF14319.1 KLO14636.1 - 0.16 11.4 3.4 0.18 11.3 2.4 1.1 1 0 0 1 1 1 0 Transposase zinc-binding domain Abhydrolase_5 PF12695.2 KLO14639.1 - 0.044 13.5 0.2 0.091 12.5 0.1 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase family Git3 PF11710.3 KLO14640.1 - 3.3e-06 26.8 6.7 8.1e-06 25.5 4.7 1.6 1 1 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 Git3_C PF11970.3 KLO14640.1 - 0.087 12.6 0.1 0.087 12.6 0.1 2.2 3 0 0 3 3 3 0 G protein-coupled glucose receptor regulating Gpa2 C-term SP_C-Propep PF08999.5 KLO14641.1 - 0.45 10.0 4.3 1 8.9 0.2 2.2 2 0 0 2 2 2 0 Surfactant protein C, N terminal propeptide O-antigen_lig PF13425.1 KLO14641.1 - 4.1 7.3 17.0 0.053 13.5 2.4 2.1 1 1 1 2 2 2 0 O-antigen ligase like membrane protein Peptidase_U4 PF03419.8 KLO14641.1 - 5.7 5.9 11.7 3.5 6.6 5.5 1.9 1 1 1 2 2 2 0 Sporulation factor SpoIIGA F-box-like PF12937.2 KLO14643.1 - 8.5e-06 25.3 0.2 3e-05 23.6 0.1 2.0 1 0 0 1 1 1 1 F-box-like DUF3508 PF12018.3 KLO14643.1 - 0.048 12.6 0.1 0.089 11.7 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3508) Transferase PF02458.10 KLO14644.1 - 1.2e-12 46.9 0.0 2.2e-12 46.1 0.0 1.4 1 1 0 1 1 1 1 Transferase family Tower PF09121.5 KLO14644.1 - 0.15 12.0 0.0 0.69 9.9 0.0 1.9 2 0 0 2 2 2 0 Tower F-box-like PF12937.2 KLO14645.1 - 0.00025 20.6 0.1 0.00063 19.4 0.1 1.7 1 0 0 1 1 1 1 F-box-like F-box-like PF12937.2 KLO14646.1 - 1.1e-08 34.6 1.7 1.7e-08 34.0 0.2 2.1 2 0 0 2 2 2 1 F-box-like F-box-like PF12937.2 KLO14647.1 - 4.6e-05 23.0 0.1 0.00011 21.8 0.1 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KLO14647.1 - 1.1 9.0 5.2 2.7 7.7 2.2 2.6 2 1 0 2 2 2 0 F-box domain HSP70 PF00012.15 KLO14648.1 - 8.3e-276 915.6 6.7 9.5e-276 915.5 4.6 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 KLO14648.1 - 3.9e-16 58.5 0.1 6.7e-15 54.4 0.0 2.2 2 0 0 2 2 2 1 MreB/Mbl protein Hydantoinase_A PF01968.13 KLO14648.1 - 0.00096 18.3 0.1 0.01 14.9 0.0 2.4 1 1 1 2 2 2 1 Hydantoinase/oxoprolinase FtsA PF14450.1 KLO14648.1 - 0.0057 16.4 3.3 1.2 8.9 0.2 3.6 2 2 0 2 2 2 2 Cell division protein FtsA FGGY_C PF02782.11 KLO14648.1 - 0.0072 15.9 0.0 0.023 14.3 0.0 1.8 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain DDR PF08841.5 KLO14648.1 - 0.03 13.1 0.5 0.24 10.1 0.1 2.2 2 0 0 2 2 2 0 Diol dehydratase reactivase ATPase-like domain DUF4582 PF15189.1 KLO14648.1 - 0.067 12.4 0.1 0.16 11.1 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4582) DUF1843 PF08898.5 KLO14648.1 - 0.34 10.9 1.6 0.92 9.6 0.3 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1843) B56 PF01603.15 KLO14649.1 - 1.6e-168 560.5 9.9 1.9e-168 560.3 6.9 1.0 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) SOG2 PF10428.4 KLO14651.1 - 7.3e-54 183.0 10.9 7.3e-54 183.0 7.5 4.1 3 1 1 4 4 4 1 RAM signalling pathway protein LRR_4 PF12799.2 KLO14651.1 - 8.4e-13 47.6 0.1 1.1e-05 24.8 0.0 3.5 2 1 1 3 3 3 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KLO14651.1 - 6.2e-11 41.8 2.6 1.2e-06 28.2 0.2 3.0 2 1 1 3 3 3 2 Leucine rich repeat LRR_1 PF00560.28 KLO14651.1 - 5.9e-07 28.6 0.7 3 8.2 0.0 5.7 6 0 0 6 6 6 3 Leucine Rich Repeat LRR_7 PF13504.1 KLO14651.1 - 0.0017 18.2 2.0 16 6.2 0.0 4.8 4 0 0 4 4 4 1 Leucine rich repeat F-box-like PF12937.2 KLO14652.1 - 3.2e-08 33.1 1.6 7.1e-08 32.0 0.1 2.3 2 0 0 2 2 2 1 F-box-like DUF3510 PF12022.3 KLO14652.1 - 0.0026 17.8 0.2 0.016 15.2 0.1 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF3510) EAP30 PF04157.11 KLO14652.1 - 0.077 12.1 0.1 1.9 7.5 0.0 2.3 2 0 0 2 2 2 0 EAP30/Vps36 family DUF3165 PF11364.3 KLO14653.1 - 0.039 14.0 0.7 0.053 13.6 0.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3165) zf-C2H2_6 PF13912.1 KLO14654.1 - 0.0063 16.3 0.5 0.0096 15.7 0.3 1.4 1 1 0 1 1 1 1 C2H2-type zinc finger zf-C2H2 PF00096.21 KLO14654.1 - 0.03 14.6 1.6 0.057 13.7 1.1 1.5 1 0 0 1 1 1 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KLO14654.1 - 0.032 14.5 1.5 0.032 14.5 1.0 1.7 2 0 0 2 2 2 0 C2H2-type zinc finger F-box-like PF12937.2 KLO14655.1 - 0.0014 18.3 0.5 0.006 16.2 0.3 2.2 1 0 0 1 1 1 1 F-box-like SRP54 PF00448.17 KLO14656.1 - 2.5e-73 245.7 1.5 4.3e-73 244.9 1.0 1.4 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain SRP_SPB PF02978.14 KLO14656.1 - 5.8e-21 74.7 0.0 5.8e-21 74.7 0.0 5.1 2 2 2 4 4 3 1 Signal peptide binding domain SRP54_N PF02881.14 KLO14656.1 - 1.6e-15 56.9 2.0 3.4e-15 55.9 1.4 1.6 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain cobW PF02492.14 KLO14656.1 - 2.8e-07 30.1 0.3 5.7e-07 29.1 0.2 1.5 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain AAA_33 PF13671.1 KLO14656.1 - 3.8e-06 26.8 0.1 8.1e-06 25.7 0.1 1.5 1 0 0 1 1 1 1 AAA domain MobB PF03205.9 KLO14656.1 - 0.0014 18.3 0.1 0.0034 17.1 0.0 1.7 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B Zeta_toxin PF06414.7 KLO14656.1 - 0.0019 17.3 0.0 0.0039 16.2 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin CbiA PF01656.18 KLO14656.1 - 0.0068 15.8 0.2 0.037 13.4 0.2 2.1 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain ArgK PF03308.11 KLO14656.1 - 0.013 14.3 3.1 0.021 13.6 0.1 2.7 2 1 1 3 3 3 0 ArgK protein AAA_17 PF13207.1 KLO14656.1 - 0.02 15.6 0.0 0.05 14.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain DUF3223 PF11523.3 KLO14656.1 - 0.024 14.9 0.1 0.06 13.6 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3223) DUF1768 PF08719.6 KLO14656.1 - 0.035 13.8 0.0 0.087 12.5 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1768) SRPRB PF09439.5 KLO14656.1 - 0.043 13.0 1.5 4.9 6.3 0.1 2.7 2 1 1 3 3 3 0 Signal recognition particle receptor beta subunit AAA_22 PF13401.1 KLO14656.1 - 0.083 13.0 0.0 0.28 11.3 0.0 1.9 1 0 0 1 1 1 0 AAA domain DUF2201 PF09967.4 KLO14656.1 - 0.1 12.5 0.9 0.56 10.2 0.2 2.5 3 0 0 3 3 2 0 VWA-like domain (DUF2201) Prion_bPrPp PF11587.3 KLO14657.1 - 0.076 12.6 0.3 0.17 11.6 0.2 1.5 1 0 0 1 1 1 0 Major prion protein bPrPp - N terminal Corona_S2 PF01601.11 KLO14660.1 - 0.19 9.7 0.4 0.25 9.3 0.3 1.1 1 0 0 1 1 1 0 Coronavirus S2 glycoprotein AA_permease_2 PF13520.1 KLO14661.1 - 2.8e-57 194.1 57.6 3.6e-57 193.8 39.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 KLO14661.1 - 5e-17 61.4 50.9 6.8e-17 60.9 35.3 1.1 1 0 0 1 1 1 1 Amino acid permease Herpes_US9 PF06072.6 KLO14661.1 - 1.4 8.7 0.0 1.4 8.7 0.0 3.9 4 1 1 5 5 5 0 Alphaherpesvirus tegument protein US9 AA_permease_2 PF13520.1 KLO14662.1 - 6.3e-63 212.7 52.2 7.5e-63 212.5 36.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 KLO14662.1 - 6.6e-18 64.3 44.2 9e-18 63.8 30.6 1.1 1 0 0 1 1 1 1 Amino acid permease ROKNT PF08067.6 KLO14662.1 - 0.03 14.1 2.3 0.051 13.4 1.6 1.3 1 0 0 1 1 1 0 ROKNT (NUC014) domain Herpes_US9 PF06072.6 KLO14662.1 - 3.5 7.5 0.0 3.5 7.5 0.0 3.9 4 0 0 4 4 4 0 Alphaherpesvirus tegument protein US9 LSM14 PF12701.2 KLO14663.1 - 3.1e-25 87.8 0.0 8.2e-25 86.4 0.0 1.7 1 0 0 1 1 1 1 Scd6-like Sm domain FDF PF09532.5 KLO14663.1 - 8.8e-10 39.0 3.0 8.8e-10 39.0 2.1 2.2 2 0 0 2 2 2 1 FDF domain SM-ATX PF14438.1 KLO14663.1 - 0.0063 16.4 0.0 0.013 15.3 0.0 1.6 1 0 0 1 1 1 1 Ataxin 2 SM domain HAD PF12710.2 KLO14664.1 - 4.8e-13 49.7 0.0 3.1e-12 47.0 0.0 2.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 KLO14664.1 - 1.5e-12 48.3 2.0 1.7e-07 31.9 0.3 3.2 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.15 KLO14664.1 - 7.8e-12 44.7 0.0 1.9e-11 43.4 0.0 1.6 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase_like2 PF13246.1 KLO14664.1 - 9.7e-10 38.2 0.0 2.3e-09 37.0 0.0 1.6 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 KLO14664.1 - 0.0014 18.2 0.5 0.0037 16.8 0.3 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase PsbW PF07123.7 KLO14665.1 - 0.071 13.1 0.8 0.12 12.4 0.5 1.3 1 0 0 1 1 1 0 Photosystem II reaction centre W protein (PsbW) DUF4131 PF13567.1 KLO14665.1 - 0.53 9.6 3.4 14 4.9 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) FAM163 PF15069.1 KLO14665.1 - 1.8 9.1 5.4 0.85 10.1 1.7 2.0 2 0 0 2 2 2 0 FAM163 family ODV-E18 PF10717.4 KLO14665.1 - 2.4 7.6 4.1 1.9 7.9 1.3 1.9 2 0 0 2 2 2 0 Occlusion-derived virus envelope protein ODV-E18 Adeno_E3_CR2 PF02439.10 KLO14665.1 - 3.1 7.4 6.9 7.9 6.1 4.8 1.6 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Hydrophobin PF01185.13 KLO14666.1 - 0.0049 17.2 1.7 0.009 16.4 1.2 1.5 1 0 0 1 1 1 1 Fungal hydrophobin Pox_A14 PF05767.7 KLO14669.1 - 0.092 12.7 0.2 0.12 12.3 0.1 1.1 1 0 0 1 1 1 0 Poxvirus virion envelope protein A14 Pkinase_Tyr PF07714.12 KLO14673.1 - 3.8e-05 22.8 0.0 6.4e-05 22.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 KLO14673.1 - 8.7e-05 21.7 0.0 0.0002 20.5 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain ATE_C PF04377.10 KLO14673.1 - 0.089 12.8 0.0 0.31 11.1 0.0 1.9 2 0 0 2 2 2 0 Arginine-tRNA-protein transferase, C terminus DUF1399 PF07173.7 KLO14675.1 - 7.2e-08 32.8 0.0 0.00027 21.2 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF1399) Lar_restr_allev PF14354.1 KLO14675.1 - 0.035 14.3 3.2 0.068 13.4 2.2 1.4 1 0 0 1 1 1 0 Restriction alleviation protein Lar Sgf11 PF08209.6 KLO14675.1 - 0.14 11.5 3.4 0.13 11.6 0.5 2.0 2 0 0 2 2 2 0 Sgf11 (transcriptional regulation protein) Sec66 PF09802.4 KLO14676.1 - 2.5e-40 137.9 0.0 3.1e-40 137.5 0.0 1.1 1 0 0 1 1 1 1 Preprotein translocase subunit Sec66 SRP-alpha_N PF04086.8 KLO14676.1 - 0.13 11.6 11.2 0.15 11.4 7.8 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal USP7_ICP0_bdg PF12436.3 KLO14677.1 - 3.4e-83 278.7 3.9 3.6e-82 275.3 1.5 2.3 2 0 0 2 2 2 1 ICP0-binding domain of Ubiquitin-specific protease 7 USP7_C2 PF14533.1 KLO14677.1 - 1.8e-64 217.1 8.0 6.2e-64 215.3 0.7 3.5 3 1 1 4 4 4 2 Ubiquitin-specific protease C-terminal UCH PF00443.24 KLO14677.1 - 1.7e-59 201.1 0.4 2.7e-59 200.4 0.3 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 KLO14677.1 - 1.6e-36 126.2 0.2 6.3e-36 124.3 0.0 1.9 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase MATH PF00917.21 KLO14677.1 - 6.5e-07 29.6 0.0 4.1e-06 27.0 0.0 2.5 2 1 0 2 2 2 1 MATH domain DUF1777 PF08648.7 KLO14678.1 - 0.0018 18.0 39.3 0.0018 18.0 27.2 3.1 2 0 0 2 2 2 2 Protein of unknown function (DUF1777) Methyltransf_23 PF13489.1 KLO14679.1 - 2.5e-13 50.0 0.0 4e-13 49.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KLO14679.1 - 5.9e-12 45.4 0.0 3.5e-11 42.9 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KLO14679.1 - 5.2e-09 36.4 0.0 1.7e-08 34.8 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KLO14679.1 - 4.1e-08 33.5 0.0 1.2e-07 32.0 0.0 1.8 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KLO14679.1 - 2.3e-06 28.1 0.0 5.8e-05 23.6 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 KLO14679.1 - 0.00012 21.1 0.0 0.00028 20.0 0.0 1.5 1 0 0 1 1 1 1 Putative methyltransferase GidB PF02527.10 KLO14679.1 - 0.00089 18.4 0.0 0.2 10.7 0.0 2.2 2 0 0 2 2 2 2 rRNA small subunit methyltransferase G Methyltransf_26 PF13659.1 KLO14679.1 - 0.00096 19.1 0.0 0.083 12.9 0.0 2.9 2 1 0 2 2 2 1 Methyltransferase domain PrmA PF06325.8 KLO14679.1 - 0.0014 17.8 0.0 0.0023 17.1 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_25 PF13649.1 KLO14679.1 - 0.0021 18.3 0.0 0.0062 16.8 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KLO14679.1 - 0.008 15.5 0.0 0.45 9.8 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase small domain FtsJ PF01728.14 KLO14679.1 - 0.12 12.3 0.0 0.18 11.7 0.0 1.3 1 0 0 1 1 1 0 FtsJ-like methyltransferase Methyltransf_15 PF09445.5 KLO14679.1 - 0.16 11.5 0.0 0.26 10.8 0.0 1.2 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase Septin PF00735.13 KLO14680.1 - 3e-114 380.7 1.0 3.6e-114 380.5 0.7 1.0 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.18 KLO14680.1 - 4.9e-08 32.9 0.0 2.6e-07 30.5 0.0 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase AIG1 PF04548.11 KLO14680.1 - 1.2e-06 27.7 0.0 2.5e-06 26.7 0.0 1.6 1 0 0 1 1 1 1 AIG1 family DUF258 PF03193.11 KLO14680.1 - 5.7e-06 25.6 0.0 9.3e-06 24.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 GTP_EFTU PF00009.22 KLO14680.1 - 7.3e-05 22.2 0.3 0.00051 19.5 0.0 2.1 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain Dynamin_N PF00350.18 KLO14680.1 - 0.00011 22.1 0.4 0.11 12.3 0.1 2.4 1 1 1 2 2 2 2 Dynamin family FtsK_SpoIIIE PF01580.13 KLO14680.1 - 0.00013 21.5 0.0 0.00024 20.6 0.0 1.4 1 0 0 1 1 1 1 FtsK/SpoIIIE family ABC_tran PF00005.22 KLO14680.1 - 0.00054 20.2 0.0 0.0013 19.0 0.0 1.6 1 0 0 1 1 1 1 ABC transporter T2SE PF00437.15 KLO14680.1 - 0.00084 18.3 0.1 0.0023 16.8 0.1 1.7 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_10 PF12846.2 KLO14680.1 - 0.002 17.6 0.2 0.0044 16.4 0.1 1.5 1 1 0 1 1 1 1 AAA-like domain Gtr1_RagA PF04670.7 KLO14680.1 - 0.0039 16.3 0.1 0.014 14.5 0.0 1.8 2 0 0 2 2 2 1 Gtr1/RagA G protein conserved region NB-ARC PF00931.17 KLO14680.1 - 0.0044 15.9 0.1 0.0092 14.8 0.1 1.5 1 0 0 1 1 1 1 NB-ARC domain AAA_16 PF13191.1 KLO14680.1 - 0.012 15.5 0.0 0.023 14.6 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.1 KLO14680.1 - 0.013 15.6 0.0 0.028 14.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain Miro PF08477.8 KLO14680.1 - 0.018 15.5 0.0 0.045 14.2 0.0 1.7 1 0 0 1 1 1 0 Miro-like protein AAA_14 PF13173.1 KLO14680.1 - 0.024 14.5 0.2 0.17 11.7 0.0 2.4 2 1 0 2 2 2 0 AAA domain AAA_29 PF13555.1 KLO14680.1 - 0.026 14.0 0.0 0.053 13.0 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain IIGP PF05049.8 KLO14680.1 - 0.037 12.8 0.2 0.098 11.4 0.0 1.7 2 0 0 2 2 2 0 Interferon-inducible GTPase (IIGP) Ras PF00071.17 KLO14680.1 - 0.061 12.7 0.1 0.22 10.9 0.0 1.9 2 1 0 2 2 2 0 Ras family AAA_17 PF13207.1 KLO14680.1 - 0.064 14.0 3.2 3.1 8.6 2.2 2.5 1 1 0 1 1 1 0 AAA domain AAA_23 PF13476.1 KLO14680.1 - 0.11 12.8 0.8 0.14 12.4 0.5 1.6 1 1 0 1 1 1 0 AAA domain Beta-lactamase PF00144.19 KLO14681.1 - 2.4e-41 141.8 0.0 3.3e-41 141.4 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase DUF1524 PF07510.6 KLO14681.1 - 0.12 12.1 1.2 0.45 10.3 0.1 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF1524) Aha1_N PF09229.6 KLO14682.1 - 1.2e-27 96.4 0.1 2e-27 95.6 0.1 1.4 1 0 0 1 1 1 1 Activator of Hsp90 ATPase, N-terminal AHSA1 PF08327.6 KLO14682.1 - 2.7e-15 56.5 0.0 7.6e-15 55.1 0.0 1.7 1 0 0 1 1 1 1 Activator of Hsp90 ATPase homolog 1-like protein Polyketide_cyc2 PF10604.4 KLO14682.1 - 0.00061 19.9 0.4 0.0084 16.2 0.0 2.2 2 0 0 2 2 2 1 Polyketide cyclase / dehydrase and lipid transport Tetraspannin PF00335.15 KLO14683.1 - 5.2e-12 45.5 13.7 7.1e-12 45.0 9.5 1.2 1 0 0 1 1 1 1 Tetraspanin family HTH_Tnp_Tc5 PF03221.11 KLO14684.1 - 0.012 15.3 0.2 1.3 8.9 0.0 2.7 2 1 0 3 3 3 0 Tc5 transposase DNA-binding domain DDE_1 PF03184.14 KLO14685.1 - 4.1e-29 101.2 0.0 4.9e-29 101.0 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_3 PF13358.1 KLO14685.1 - 7.8e-05 22.4 0.0 0.00014 21.6 0.0 1.5 1 1 0 1 1 1 1 DDE superfamily endonuclease Smg4_UPF3 PF03467.10 KLO14686.1 - 0.016 15.1 0.0 0.027 14.4 0.0 1.3 1 0 0 1 1 1 0 Smg-4/UPF3 family TMP-TENI PF02581.12 KLO14687.1 - 0.12 11.4 0.0 0.46 9.5 0.0 1.7 1 1 1 2 2 2 0 Thiamine monophosphate synthase/TENI SoxE PF06525.6 KLO14687.1 - 0.13 11.5 0.0 0.16 11.2 0.0 1.1 1 0 0 1 1 1 0 Sulfocyanin (SoxE) SMI1_KNR4 PF09346.5 KLO14689.1 - 1.3e-23 83.3 0.0 2.3e-23 82.6 0.0 1.3 1 0 0 1 1 1 1 SMI1 / KNR4 family (SUKH-1) HSA PF07529.8 KLO14690.1 - 1.2e-15 57.0 1.2 1.2e-15 57.0 0.8 3.0 2 0 0 2 2 2 1 HSA Myb_DNA-bind_6 PF13921.1 KLO14690.1 - 6.9e-06 26.0 0.9 2.1e-05 24.5 0.7 1.9 1 0 0 1 1 1 1 Myb-like DNA-binding domain 2OG-FeII_Oxy_2 PF13532.1 KLO14691.1 - 1.5e-23 83.6 0.0 1.9e-23 83.3 0.0 1.2 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DUF1399 PF07173.7 KLO14692.1 - 3.8e-09 36.9 0.0 9.5e-06 25.9 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF1399) FYVE PF01363.16 KLO14693.1 - 9e-17 60.7 1.2 1.7e-16 59.8 0.8 1.4 1 0 0 1 1 1 1 FYVE zinc finger Rbsn PF11464.3 KLO14693.1 - 0.00011 21.6 1.2 0.00025 20.5 0.4 1.9 2 0 0 2 2 2 1 Rabenosyn Rab binding domain zf-C2HC5 PF06221.8 KLO14693.1 - 0.0036 17.0 3.3 0.0036 17.0 2.3 1.8 2 0 0 2 2 2 1 Putative zinc finger motif, C2HC5-type DUF4206 PF13901.1 KLO14693.1 - 0.013 15.1 0.2 0.024 14.2 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4206) FYVE_2 PF02318.11 KLO14693.1 - 0.27 11.1 3.9 0.22 11.4 0.4 2.2 2 0 0 2 2 2 0 FYVE-type zinc finger SPX PF03105.14 KLO14694.1 - 1.2e-17 64.5 0.0 4.1e-16 59.5 0.0 2.5 1 1 0 1 1 1 1 SPX domain zf-C3HC4_4 PF15227.1 KLO14694.1 - 1.6e-06 27.9 11.9 6.4e-06 25.9 8.4 1.9 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.20 KLO14694.1 - 2.3e-05 23.9 13.1 3.7e-05 23.2 9.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KLO14694.1 - 2.9e-05 23.8 13.2 4.8e-05 23.1 9.2 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 KLO14694.1 - 3.9e-05 23.2 10.3 6.2e-05 22.5 7.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KLO14694.1 - 6.6e-05 22.8 14.4 0.00012 21.9 10.0 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KLO14694.1 - 0.0014 18.2 12.7 0.0025 17.4 8.8 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_4 PF14570.1 KLO14694.1 - 0.016 14.8 6.5 0.031 13.8 4.5 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING_6 PF14835.1 KLO14694.1 - 0.061 13.1 5.7 0.12 12.1 4.0 1.4 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-RING_UBOX PF13445.1 KLO14694.1 - 0.092 12.4 14.3 0.05 13.3 7.7 2.2 2 0 0 2 2 2 0 RING-type zinc-finger Zn_clus PF00172.13 KLO14695.1 - 0.0076 16.1 7.8 0.01 15.7 5.4 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Plug_translocon PF10559.4 KLO14695.1 - 0.11 12.0 0.1 0.22 11.0 0.0 1.6 1 0 0 1 1 1 0 Plug domain of Sec61p Zn_clus PF00172.13 KLO14696.1 - 0.099 12.5 9.8 0.21 11.4 6.8 1.6 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Swi3 PF07962.7 KLO14697.1 - 2.5e-23 81.4 0.1 3.4e-23 81.0 0.1 1.2 1 0 0 1 1 1 1 Replication Fork Protection Component Swi3 Methyltransf_PK PF05891.7 KLO14698.1 - 2.7e-53 180.4 0.0 3e-51 173.8 0.0 2.2 1 1 0 1 1 1 1 AdoMet dependent proline di-methyltransferase Methyltransf_23 PF13489.1 KLO14698.1 - 0.00025 20.8 0.0 0.0004 20.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KLO14698.1 - 0.0056 17.2 0.0 0.01 16.3 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KLO14698.1 - 0.031 14.7 0.0 0.33 11.4 0.0 2.2 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_2 PF00891.13 KLO14698.1 - 0.054 12.6 0.0 0.42 9.7 0.0 2.0 2 0 0 2 2 2 0 O-methyltransferase Methyltransf_11 PF08241.7 KLO14698.1 - 0.1 13.0 0.0 5.2 7.6 0.0 2.4 1 1 0 1 1 1 0 Methyltransferase domain DUF605 PF04652.11 KLO14699.1 - 0.077 12.3 4.0 0.091 12.1 2.8 1.1 1 0 0 1 1 1 0 Vta1 like SH2_2 PF14633.1 KLO14700.1 - 2.8e-65 219.4 0.5 2.8e-65 219.4 0.3 2.3 2 0 0 2 2 2 1 SH2 domain DLD PF14878.1 KLO14700.1 - 3.1e-29 101.3 0.7 3.1e-29 101.3 0.5 3.2 3 0 0 3 3 3 1 Death-like domain of SPT6 HHH_7 PF14635.1 KLO14700.1 - 3.3e-28 97.8 0.0 9.6e-28 96.3 0.0 1.8 1 0 0 1 1 1 1 Helix-hairpin-helix motif YqgF PF14639.1 KLO14700.1 - 5e-27 94.3 0.0 1.1e-26 93.2 0.0 1.6 1 0 0 1 1 1 1 Holliday-junction resolvase-like of SPT6 SPT6_acidic PF14632.1 KLO14700.1 - 5.4e-20 71.3 36.1 5.4e-20 71.3 25.0 4.4 5 1 0 6 6 6 1 Acidic N-terminal SPT6 HTH_44 PF14641.1 KLO14700.1 - 9.3e-15 54.6 0.1 9.3e-15 54.6 0.1 2.1 2 0 0 2 2 2 1 Helix-turn-helix DNA-binding domain of SPT6 SH2 PF00017.19 KLO14700.1 - 2.6e-06 27.1 0.0 5.7e-05 22.8 0.0 2.7 2 0 0 2 2 2 1 SH2 domain S1 PF00575.18 KLO14700.1 - 9.4e-05 22.4 1.9 0.00022 21.2 1.3 1.6 1 0 0 1 1 1 1 S1 RNA binding domain HHH_3 PF12836.2 KLO14700.1 - 0.0016 18.3 0.0 0.029 14.3 0.0 2.6 2 0 0 2 2 2 1 Helix-hairpin-helix motif NAD_binding_10 PF13460.1 KLO14701.1 - 1.2e-12 48.2 0.0 3.5e-11 43.4 0.0 2.4 2 1 0 2 2 2 1 NADH(P)-binding Epimerase PF01370.16 KLO14701.1 - 3.9e-12 46.1 0.1 3e-08 33.4 0.0 3.0 3 0 0 3 3 3 2 NAD dependent epimerase/dehydratase family adh_short PF00106.20 KLO14701.1 - 0.0014 18.5 0.0 0.007 16.2 0.0 2.0 2 0 0 2 2 2 1 short chain dehydrogenase 3Beta_HSD PF01073.14 KLO14701.1 - 0.002 16.9 0.0 0.0051 15.5 0.0 1.7 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family NmrA PF05368.8 KLO14701.1 - 0.11 11.6 0.1 0.45 9.7 0.0 1.9 2 0 0 2 2 2 0 NmrA-like family DPBB_1 PF03330.13 KLO14702.1 - 2.5e-11 43.3 1.8 4.7e-11 42.5 0.1 2.3 2 0 0 2 2 2 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Barwin PF00967.12 KLO14702.1 - 4.9e-05 22.9 0.7 0.00013 21.6 0.5 1.6 1 0 0 1 1 1 1 Barwin family DUF572 PF04502.8 KLO14702.1 - 0.23 10.6 5.8 0.3 10.2 4.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) SIT PF15330.1 KLO14702.1 - 0.4 10.8 2.4 0.83 9.8 0.0 2.4 2 1 0 2 2 2 0 SHP2-interacting transmembrane adaptor protein, SIT YL1 PF05764.8 KLO14702.1 - 1 8.9 8.3 1.4 8.4 5.8 1.1 1 0 0 1 1 1 0 YL1 nuclear protein Med3 PF11593.3 KLO14702.1 - 3 7.0 23.3 0.082 12.1 6.7 2.1 2 0 0 2 2 2 0 Mediator complex subunit 3 fungal Nop14 PF04147.7 KLO14702.1 - 3.8 5.3 14.4 4.7 4.9 10.0 1.0 1 0 0 1 1 1 0 Nop14-like family Pneumo_att_G PF05539.6 KLO14702.1 - 9.1 5.5 25.5 13 5.0 17.7 1.2 1 0 0 1 1 1 0 Pneumovirinae attachment membrane glycoprotein G Macoilin PF09726.4 KLO14702.1 - 9.5 4.3 8.1 11 4.0 5.6 1.2 1 0 0 1 1 1 0 Transmembrane protein SCAMP PF04144.8 KLO14703.1 - 1.4e-35 122.7 3.2 1.7e-35 122.4 2.2 1.1 1 0 0 1 1 1 1 SCAMP family APH PF01636.18 KLO14703.1 - 0.095 12.4 0.1 0.14 11.9 0.1 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family Milton PF12448.3 KLO14703.1 - 0.13 12.3 1.5 0.2 11.8 1.1 1.2 1 0 0 1 1 1 0 Kinesin associated protein Pox_A14 PF05767.7 KLO14703.1 - 0.6 10.1 3.2 1 9.3 0.4 2.1 2 0 0 2 2 2 0 Poxvirus virion envelope protein A14 RRM_1 PF00076.17 KLO14704.1 - 5.1e-80 263.1 6.6 3.6e-20 71.3 0.4 4.3 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KLO14704.1 - 2.8e-58 193.8 1.0 1.7e-16 59.9 0.0 4.4 4 0 0 4 4 4 4 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KLO14704.1 - 1.5e-44 149.6 1.1 2.6e-11 43.1 0.0 4.4 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PABP PF00658.13 KLO14704.1 - 1.1e-27 95.4 2.4 2e-27 94.6 0.8 2.1 2 0 0 2 2 2 1 Poly-adenylate binding protein, unique domain RRM_3 PF08777.6 KLO14704.1 - 0.00012 21.8 12.2 0.2 11.5 2.7 3.8 4 0 0 4 4 4 3 RNA binding motif Limkain-b1 PF11608.3 KLO14704.1 - 0.00098 18.8 3.3 0.5 10.1 0.2 3.5 3 0 0 3 3 3 1 Limkain b1 CbiG_mid PF11761.3 KLO14704.1 - 0.0064 16.7 0.3 0.21 11.8 0.0 2.9 3 0 0 3 3 2 1 Cobalamin biosynthesis central region OB_RNB PF08206.6 KLO14704.1 - 0.025 14.0 2.4 7.8 6.0 0.2 3.3 3 0 0 3 3 3 0 Ribonuclease B OB domain DUF1919 PF08942.5 KLO14704.1 - 0.042 13.2 1.1 0.2 10.9 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1919) Nup35_RRM_2 PF14605.1 KLO14704.1 - 0.1 12.4 0.5 31 4.4 0.0 3.7 4 0 0 4 4 4 0 Nup53/35/40-type RNA recognition motif CSD PF00313.17 KLO14704.1 - 0.13 12.0 1.5 27 4.6 0.0 3.3 3 0 0 3 3 3 0 'Cold-shock' DNA-binding domain PNPase PF03726.9 KLO14704.1 - 0.21 11.8 4.9 0.29 11.4 0.1 2.6 2 0 0 2 2 2 0 Polyribonucleotide nucleotidyltransferase, RNA binding domain DUF4407 PF14362.1 KLO14704.1 - 8.9 5.1 8.7 2.4 7.0 3.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Caudo_TAP PF02413.12 KLO14704.1 - 9.2 6.4 9.3 9.4 6.4 0.4 3.1 3 0 0 3 3 3 0 Caudovirales tail fibre assembly protein Methyltransf_23 PF13489.1 KLO14705.1 - 1.8e-18 66.8 0.0 2.9e-18 66.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KLO14705.1 - 6e-15 55.5 0.0 1.1e-14 54.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KLO14705.1 - 1.8e-13 50.3 0.0 2e-12 46.9 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KLO14705.1 - 2.6e-11 44.0 0.0 2.4e-10 40.9 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KLO14705.1 - 1e-08 35.5 0.0 7.8e-08 32.7 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KLO14705.1 - 2.1e-07 31.2 0.0 8.9e-07 29.2 0.0 2.1 2 1 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.13 KLO14705.1 - 3.3e-07 29.6 0.0 3.9e-06 26.1 0.0 2.2 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_29 PF03141.11 KLO14705.1 - 1.6e-06 26.7 0.0 5.4e-06 25.0 0.0 1.7 1 1 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_4 PF02390.12 KLO14705.1 - 5.3e-06 25.6 0.0 0.00041 19.4 0.0 2.2 2 0 0 2 2 2 1 Putative methyltransferase Methyltransf_8 PF05148.10 KLO14705.1 - 4.2e-05 23.2 0.0 0.00014 21.5 0.0 1.8 2 0 0 2 2 2 1 Hypothetical methyltransferase CMAS PF02353.15 KLO14705.1 - 0.00021 20.4 0.0 0.00046 19.3 0.0 1.5 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_26 PF13659.1 KLO14705.1 - 0.00078 19.4 0.0 0.0024 17.8 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KLO14705.1 - 0.0086 15.4 0.0 0.016 14.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Sec63 PF02889.11 KLO14705.1 - 0.015 14.5 0.0 0.021 14.0 0.0 1.1 1 0 0 1 1 1 0 Sec63 Brl domain DUF938 PF06080.7 KLO14705.1 - 0.028 13.9 0.0 0.049 13.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF938) FtsJ PF01728.14 KLO14705.1 - 0.031 14.2 0.0 0.057 13.4 0.0 1.3 1 0 0 1 1 1 0 FtsJ-like methyltransferase Methyltransf_2 PF00891.13 KLO14705.1 - 0.078 12.1 0.0 0.21 10.7 0.0 1.6 2 0 0 2 2 2 0 O-methyltransferase WD40 PF00400.27 KLO14706.1 - 4.7e-07 29.4 7.5 0.00092 19.0 0.5 3.3 3 0 0 3 3 3 3 WD domain, G-beta repeat DEAD PF00270.24 KLO14707.1 - 1.4e-06 27.8 0.1 1.5e-06 27.8 0.1 1.1 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.10 KLO14707.1 - 0.0026 17.6 0.1 0.0026 17.6 0.0 1.1 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit adh_short PF00106.20 KLO14709.1 - 5.9e-31 107.6 0.6 7.5e-31 107.2 0.4 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KLO14709.1 - 8.4e-16 58.1 0.6 1.3e-15 57.5 0.4 1.2 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 KLO14709.1 - 1.9e-15 57.3 0.0 2.5e-15 56.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 KLO14709.1 - 3.9e-06 27.0 0.1 9.4e-06 25.7 0.1 1.5 1 1 0 1 1 1 1 NADH(P)-binding 3HCDH_N PF02737.13 KLO14709.1 - 0.00018 21.2 0.6 0.0003 20.4 0.4 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Epimerase PF01370.16 KLO14709.1 - 0.00019 20.9 0.0 0.0003 20.2 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family F420_oxidored PF03807.12 KLO14709.1 - 0.0017 18.7 0.4 0.0041 17.5 0.2 1.7 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Shikimate_DH PF01488.15 KLO14709.1 - 0.002 18.2 0.6 0.0058 16.7 0.4 1.8 1 1 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase THF_DHG_CYH_C PF02882.14 KLO14709.1 - 0.0063 15.6 0.1 0.037 13.1 0.0 2.1 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain ApbA PF02558.11 KLO14709.1 - 0.0069 15.8 0.1 0.01 15.2 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA NAD_binding_7 PF13241.1 KLO14709.1 - 0.034 14.4 0.2 0.1 12.8 0.1 1.7 1 0 0 1 1 1 0 Putative NAD(P)-binding adh_short PF00106.20 KLO14710.1 - 1.5e-29 103.0 0.7 2e-29 102.6 0.5 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KLO14710.1 - 6e-15 55.6 0.0 7.8e-15 55.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KLO14710.1 - 5.7e-11 42.4 0.4 8.7e-11 41.8 0.3 1.2 1 0 0 1 1 1 1 KR domain NAD_Gly3P_dh_N PF01210.18 KLO14710.1 - 0.0022 17.7 0.1 0.0038 16.9 0.1 1.4 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Shikimate_DH PF01488.15 KLO14710.1 - 0.0024 17.9 0.3 0.0049 16.9 0.2 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase ApbA PF02558.11 KLO14710.1 - 0.0036 16.7 0.1 0.006 16.0 0.1 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA 3HCDH_N PF02737.13 KLO14710.1 - 0.015 14.9 0.4 0.015 14.9 0.3 1.6 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain THF_DHG_CYH_C PF02882.14 KLO14710.1 - 0.029 13.4 0.0 0.077 12.0 0.0 1.7 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Eno-Rase_NADH_b PF12242.3 KLO14710.1 - 0.049 13.4 0.1 0.11 12.3 0.1 1.6 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase NAD_binding_10 PF13460.1 KLO14710.1 - 0.052 13.5 1.3 0.15 12.0 0.9 1.9 1 1 0 1 1 1 0 NADH(P)-binding adh_short PF00106.20 KLO14711.1 - 6.4e-30 104.2 2.1 9.5e-30 103.7 1.4 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KLO14711.1 - 1.3e-18 67.7 0.1 1.7e-18 67.3 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KLO14711.1 - 3.1e-13 49.7 1.1 5.3e-13 49.0 0.7 1.3 1 0 0 1 1 1 1 KR domain ApbA PF02558.11 KLO14711.1 - 0.00012 21.5 0.1 0.00023 20.6 0.1 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Shikimate_DH PF01488.15 KLO14711.1 - 0.00031 20.8 1.1 0.00073 19.6 0.2 2.0 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase 3HCDH_N PF02737.13 KLO14711.1 - 0.0011 18.6 1.3 0.0011 18.6 0.2 1.5 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_10 PF13460.1 KLO14711.1 - 0.0014 18.6 1.4 0.0027 17.7 0.8 1.9 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 KLO14711.1 - 0.0018 17.7 0.0 0.0029 17.0 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_Gly3P_dh_N PF01210.18 KLO14711.1 - 0.0045 16.7 1.2 0.013 15.2 0.1 2.2 3 0 0 3 3 3 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus GHMP_kinases_C PF08544.8 KLO14711.1 - 0.0099 16.0 0.6 0.028 14.6 0.2 2.0 2 0 0 2 2 1 1 GHMP kinases C terminal THF_DHG_CYH_C PF02882.14 KLO14711.1 - 0.013 14.5 0.1 0.062 12.3 0.0 2.0 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain NAD_binding_7 PF13241.1 KLO14711.1 - 0.087 13.0 0.1 0.25 11.6 0.1 1.8 2 0 0 2 2 2 0 Putative NAD(P)-binding adh_short PF00106.20 KLO14712.1 - 4.1e-27 95.1 1.0 5.9e-27 94.6 0.7 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KLO14712.1 - 8.3e-18 65.0 0.1 1.1e-17 64.6 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KLO14712.1 - 1.2e-10 41.4 0.4 3.5e-10 39.8 0.2 1.8 2 0 0 2 2 2 1 KR domain ApbA PF02558.11 KLO14712.1 - 4.9e-05 22.8 0.1 8.2e-05 22.0 0.1 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Shikimate_DH PF01488.15 KLO14712.1 - 5.9e-05 23.1 0.3 0.00013 22.1 0.2 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NAD_binding_10 PF13460.1 KLO14712.1 - 0.00032 20.7 0.9 0.00093 19.2 0.6 1.9 1 1 0 1 1 1 1 NADH(P)-binding 3HCDH_N PF02737.13 KLO14712.1 - 0.00034 20.3 1.9 0.00052 19.7 0.3 1.9 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_Gly3P_dh_N PF01210.18 KLO14712.1 - 0.00047 19.9 1.6 0.0005 19.8 0.1 1.8 3 0 0 3 3 3 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Epimerase PF01370.16 KLO14712.1 - 0.0013 18.2 0.0 0.0018 17.7 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Saccharop_dh PF03435.13 KLO14712.1 - 0.019 13.9 0.5 0.03 13.2 0.3 1.3 1 0 0 1 1 1 0 Saccharopine dehydrogenase THF_DHG_CYH_C PF02882.14 KLO14712.1 - 0.023 13.7 0.2 0.083 11.9 0.0 2.0 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain DFP PF04127.10 KLO14712.1 - 0.029 14.0 0.1 0.056 13.0 0.0 1.4 1 0 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein 2-Hacid_dh_C PF02826.14 KLO14712.1 - 0.033 13.3 0.0 0.068 12.3 0.0 1.6 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain F420_oxidored PF03807.12 KLO14712.1 - 0.037 14.4 1.3 0.098 13.1 0.3 2.0 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent Polysacc_synt_2 PF02719.10 KLO14712.1 - 0.045 12.6 0.0 0.071 11.9 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Wax2_C PF12076.3 KLO14712.1 - 0.071 12.8 0.0 0.13 11.9 0.0 1.4 1 0 0 1 1 1 0 WAX2 C-terminal domain Eno-Rase_NADH_b PF12242.3 KLO14712.1 - 0.077 12.7 3.0 0.19 11.5 1.8 1.9 1 1 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase NmrA PF05368.8 KLO14712.1 - 0.098 11.9 1.4 0.32 10.2 0.5 1.9 2 0 0 2 2 2 0 NmrA-like family COPIIcoated_ERV PF07970.7 KLO14713.1 - 4.3e-65 219.4 1.3 4.7e-65 219.3 0.3 1.5 2 0 0 2 2 2 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.1 KLO14713.1 - 2.1e-31 107.7 3.3 2.3e-31 107.6 0.2 2.4 2 1 1 3 3 3 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) adh_short PF00106.20 KLO14714.1 - 5.8e-27 94.6 0.5 2.4e-26 92.6 0.3 1.8 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.1 KLO14714.1 - 1.3e-13 51.3 0.1 1.9e-13 50.7 0.1 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KLO14714.1 - 6.9e-13 48.6 0.3 3.8e-12 46.2 0.1 1.9 2 0 0 2 2 2 1 KR domain Epimerase PF01370.16 KLO14714.1 - 6.8e-05 22.4 0.0 0.00033 20.1 0.0 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Shikimate_DH PF01488.15 KLO14714.1 - 0.00034 20.7 0.2 0.00064 19.8 0.1 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase F420_oxidored PF03807.12 KLO14714.1 - 0.00067 20.0 1.7 0.00072 19.9 0.2 1.8 2 0 0 2 2 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_10 PF13460.1 KLO14714.1 - 0.00079 19.4 0.2 0.0032 17.4 0.1 2.1 1 1 0 2 2 2 1 NADH(P)-binding THF_DHG_CYH_C PF02882.14 KLO14714.1 - 0.002 17.1 0.1 0.0046 16.0 0.0 1.6 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain 3HCDH_N PF02737.13 KLO14714.1 - 0.0049 16.5 1.4 0.006 16.2 0.2 1.7 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Polysacc_synt_2 PF02719.10 KLO14714.1 - 0.0057 15.5 0.0 0.0074 15.2 0.0 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Eno-Rase_NADH_b PF12242.3 KLO14714.1 - 0.017 14.9 0.3 0.042 13.6 0.2 1.6 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase DFP PF04127.10 KLO14714.1 - 0.019 14.5 0.5 0.039 13.5 0.3 1.5 1 1 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein ApbA PF02558.11 KLO14714.1 - 0.022 14.2 0.0 0.036 13.5 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA NAD_binding_7 PF13241.1 KLO14714.1 - 0.04 14.1 0.1 0.16 12.2 0.1 1.9 2 0 0 2 2 2 0 Putative NAD(P)-binding NAD_Gly3P_dh_N PF01210.18 KLO14714.1 - 0.042 13.5 0.2 0.089 12.5 0.0 1.6 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Saccharop_dh PF03435.13 KLO14714.1 - 0.064 12.2 0.1 0.1 11.5 0.1 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase 2-Hacid_dh_C PF02826.14 KLO14714.1 - 0.096 11.8 0.0 0.18 10.9 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AstA PF04958.7 KLO14714.1 - 0.11 10.9 0.0 0.25 9.7 0.0 1.5 2 0 0 2 2 2 0 Arginine N-succinyltransferase beta subunit adh_short PF00106.20 KLO14715.1 - 1.2e-27 96.8 0.8 1.6e-27 96.4 0.2 1.4 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.1 KLO14715.1 - 3.6e-20 72.7 0.0 4.7e-20 72.3 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KLO14715.1 - 4.7e-10 39.4 1.1 7.8e-10 38.7 0.2 1.6 2 0 0 2 2 2 1 KR domain Shikimate_DH PF01488.15 KLO14715.1 - 2.3e-05 24.5 0.4 8.6e-05 22.6 0.1 2.0 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase ApbA PF02558.11 KLO14715.1 - 8.2e-05 22.0 0.2 0.00015 21.2 0.1 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA F420_oxidored PF03807.12 KLO14715.1 - 0.0098 16.3 1.4 0.017 15.5 0.3 1.9 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_10 PF13460.1 KLO14715.1 - 0.011 15.6 0.8 0.02 14.9 0.6 1.6 1 1 0 1 1 1 0 NADH(P)-binding NAD_Gly3P_dh_N PF01210.18 KLO14715.1 - 0.012 15.3 0.6 0.098 12.3 0.1 2.2 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus 3HCDH_N PF02737.13 KLO14715.1 - 0.013 15.1 2.0 0.014 15.0 0.3 1.8 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Eno-Rase_NADH_b PF12242.3 KLO14715.1 - 0.021 14.5 0.4 0.06 13.1 0.3 1.7 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Epimerase PF01370.16 KLO14715.1 - 0.066 12.6 0.3 0.1 11.9 0.2 1.5 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family 2-Hacid_dh_C PF02826.14 KLO14715.1 - 0.067 12.3 0.8 0.23 10.5 0.2 2.2 2 1 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain SIR2 PF02146.12 KLO14716.1 - 7e-62 208.3 0.0 2e-61 206.8 0.0 1.8 3 0 0 3 3 3 1 Sir2 family Sec1 PF00995.18 KLO14717.1 - 2.9e-139 465.2 0.0 3.3e-139 465.1 0.0 1.0 1 0 0 1 1 1 1 Sec1 family DUF727 PF05303.7 KLO14718.1 - 7.9e-06 25.6 0.0 9.4e-06 25.3 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF727) DUF4131 PF13567.1 KLO14719.1 - 0.027 13.8 0.0 0.039 13.3 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) Aldo_ket_red PF00248.16 KLO14721.1 - 3.2e-45 154.1 0.0 4.8e-45 153.5 0.0 1.3 1 1 0 1 1 1 1 Aldo/keto reductase family FYRC PF05965.9 KLO14722.1 - 1.5e-16 59.9 0.0 2.6e-16 59.2 0.0 1.3 1 0 0 1 1 1 1 F/Y rich C-terminus FYRN PF05964.9 KLO14722.1 - 1.5e-16 59.5 0.1 2.4e-16 58.8 0.1 1.4 1 0 0 1 1 1 1 F/Y-rich N-terminus SpoIID PF08486.5 KLO14722.1 - 0.08 13.2 0.0 0.17 12.2 0.0 1.5 1 0 0 1 1 1 0 Stage II sporulation protein F-box-like PF12937.2 KLO14724.1 - 7.8e-10 38.3 2.6 0.00012 21.7 0.0 3.7 3 0 0 3 3 3 2 F-box-like F-box-like PF12937.2 KLO14725.1 - 0.00048 19.7 0.1 0.0027 17.3 0.0 2.4 2 1 0 2 2 2 1 F-box-like GTPase_Cys_C PF12631.2 KLO14725.1 - 0.086 13.2 0.5 2 8.8 0.0 2.6 2 0 0 2 2 2 0 Catalytic cysteine-containing C-terminus of GTPase, MnmE DUF4591 PF15261.1 KLO14725.1 - 0.3 11.3 1.5 0.85 9.8 1.0 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4591) XPG_I PF00867.13 KLO14726.1 - 9e-16 57.7 0.0 2.1e-15 56.5 0.0 1.6 1 0 0 1 1 1 1 XPG I-region Phage_integrase PF00589.17 KLO14727.1 - 0.00098 18.8 0.0 0.015 14.9 0.0 2.6 2 1 0 2 2 2 1 Phage integrase family SUR7 PF06687.7 KLO14728.1 - 9.4e-17 61.2 14.8 1.2e-15 57.7 10.2 1.9 1 1 0 1 1 1 1 SUR7/PalI family Clc-like PF07062.7 KLO14728.1 - 0.0028 16.9 1.5 0.0028 16.9 1.1 1.7 2 0 0 2 2 2 1 Clc-like DUF87 PF01935.12 KLO14728.1 - 0.041 13.6 1.0 0.058 13.2 0.7 1.1 1 0 0 1 1 1 0 Domain of unknown function DUF87 Tetraspannin PF00335.15 KLO14728.1 - 3.1 7.0 13.5 6 6.0 3.5 2.5 1 1 1 2 2 2 0 Tetraspanin family BTB PF00651.26 KLO14731.1 - 0.018 15.0 0.2 0.21 11.5 0.0 2.4 2 0 0 2 2 2 0 BTB/POZ domain Lipase_GDSL_2 PF13472.1 KLO14732.1 - 1.1e-08 35.3 0.0 1.7e-08 34.8 0.0 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 KLO14732.1 - 1.8e-08 34.5 0.0 2.4e-08 34.0 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Nha1_C PF08619.5 KLO14734.1 - 0.0029 16.9 5.1 0.0035 16.6 3.5 1.1 1 0 0 1 1 1 1 Alkali metal cation/H+ antiporter Nha1 C terminus SH3_1 PF00018.23 KLO14736.1 - 1.3e-06 27.6 0.0 2.5e-06 26.7 0.0 1.4 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 KLO14736.1 - 2.6e-06 26.8 0.0 4.7e-06 26.0 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 KLO14736.1 - 2.4e-05 23.7 0.0 4.4e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SIT PF15330.1 KLO14736.1 - 0.044 13.9 0.0 0.091 12.9 0.0 1.5 1 0 0 1 1 1 0 SHP2-interacting transmembrane adaptor protein, SIT Adaptin_binding PF10199.4 KLO14737.1 - 4.4e-12 46.4 0.7 3.2e-11 43.6 0.5 2.1 1 1 0 1 1 1 1 Alpha and gamma adaptin binding protein p34 SNF5 PF04855.7 KLO14738.1 - 1.9e-57 194.5 0.1 5.8e-57 192.9 0.1 1.7 1 1 0 1 1 1 1 SNF5 / SMARCB1 / INI1 HHH_8 PF14716.1 KLO14739.1 - 6.2e-13 48.7 0.7 9.1e-12 45.0 0.1 2.3 2 0 0 2 2 2 1 Helix-hairpin-helix domain DNA_pol_B_thumb PF14791.1 KLO14739.1 - 6.2e-12 45.0 0.0 1.4e-11 43.8 0.0 1.6 1 0 0 1 1 1 1 DNA polymerase beta thumb DNA_pol_B_palm PF14792.1 KLO14739.1 - 7.3e-10 38.9 0.0 0.00016 21.6 0.0 2.5 2 0 0 2 2 2 2 DNA polymerase beta palm DNA_pol_lambd_f PF10391.4 KLO14739.1 - 6.5e-09 35.2 0.0 1.4e-08 34.1 0.0 1.6 1 0 0 1 1 1 1 Fingers domain of DNA polymerase lambda HHH_5 PF14520.1 KLO14739.1 - 1.8e-08 34.3 0.0 1.2e-06 28.5 0.0 2.5 2 0 0 2 2 2 1 Helix-hairpin-helix domain HHH PF00633.18 KLO14739.1 - 0.00015 21.2 0.6 0.014 15.0 0.0 2.6 2 0 0 2 2 2 1 Helix-hairpin-helix motif HHH_2 PF12826.2 KLO14739.1 - 0.1 12.5 0.1 14 5.6 0.0 2.4 2 0 0 2 2 2 0 Helix-hairpin-helix motif Cdd1 PF11731.3 KLO14739.1 - 0.15 12.0 0.0 0.46 10.4 0.0 1.8 2 0 0 2 2 2 0 Pathogenicity locus DUF1049 PF06305.6 KLO14740.1 - 0.82 9.1 3.8 0.83 9.1 0.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1049) DUF2419 PF10343.4 KLO14741.1 - 8.6e-86 287.7 0.0 4.7e-85 285.3 0.0 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF2419) MukB PF04310.7 KLO14741.1 - 0.025 13.8 0.0 0.043 13.1 0.0 1.3 1 0 0 1 1 1 0 MukB N-terminal adh_short PF00106.20 KLO14743.1 - 4.3e-26 91.8 1.2 4.3e-26 91.8 0.9 1.5 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 KLO14743.1 - 2.9e-11 43.3 0.9 5.3e-11 42.5 0.6 1.3 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 KLO14743.1 - 8.8e-11 42.0 0.4 1.3e-10 41.4 0.3 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Shikimate_DH PF01488.15 KLO14743.1 - 0.0026 17.8 0.7 0.0095 16.0 0.4 2.1 1 1 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase 3HCDH_N PF02737.13 KLO14743.1 - 0.0044 16.6 0.8 0.0091 15.6 0.5 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ApbA PF02558.11 KLO14743.1 - 0.0075 15.7 0.1 0.013 14.9 0.1 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA NAD_binding_10 PF13460.1 KLO14743.1 - 0.0079 16.2 0.8 0.017 15.1 0.5 1.8 1 1 0 1 1 1 1 NADH(P)-binding THF_DHG_CYH_C PF02882.14 KLO14743.1 - 0.0096 15.0 0.3 0.045 12.8 0.0 2.1 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain DFP PF04127.10 KLO14743.1 - 0.029 13.9 1.0 0.078 12.5 0.7 1.6 1 1 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein AdoHcyase_NAD PF00670.16 KLO14743.1 - 0.069 12.9 0.3 1.8 8.3 0.0 2.7 2 1 0 2 2 2 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 2-Hacid_dh_C PF02826.14 KLO14743.1 - 0.073 12.2 0.0 0.21 10.7 0.0 1.8 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_7 PF13241.1 KLO14743.1 - 0.11 12.7 0.5 0.7 10.1 0.2 2.1 2 0 0 2 2 2 0 Putative NAD(P)-binding Eno-Rase_NADH_b PF12242.3 KLO14743.1 - 0.12 12.2 0.3 0.29 10.9 0.2 1.6 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase DUF3176 PF11374.3 KLO14744.1 - 0.1 12.5 1.3 0.41 10.5 0.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3176) DUF4271 PF14093.1 KLO14745.1 - 3.1 7.4 10.5 0.1 12.2 1.5 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4271) DUF3619 PF12279.3 KLO14746.1 - 0.069 13.2 0.0 0.18 11.9 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3619) adh_short PF00106.20 KLO14747.1 - 5.8e-28 97.9 1.6 1.1e-27 97.0 1.1 1.5 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KLO14747.1 - 4.4e-13 49.3 1.5 7.2e-13 48.5 0.7 1.5 2 0 0 2 2 2 1 KR domain adh_short_C2 PF13561.1 KLO14747.1 - 1e-09 38.5 0.1 1.2e-09 38.3 0.1 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase ApbA PF02558.11 KLO14747.1 - 0.0017 17.7 0.1 0.0027 17.1 0.1 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA 3HCDH_N PF02737.13 KLO14747.1 - 0.0018 17.9 0.8 0.0018 17.9 0.5 2.5 2 1 1 3 3 3 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_10 PF13460.1 KLO14747.1 - 0.01 15.8 1.5 0.022 14.7 0.6 2.0 2 1 0 2 2 2 0 NADH(P)-binding Shikimate_DH PF01488.15 KLO14747.1 - 0.017 15.2 0.1 0.035 14.2 0.1 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase THF_DHG_CYH_C PF02882.14 KLO14747.1 - 0.019 14.0 0.5 0.053 12.5 0.1 1.9 2 1 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Epimerase PF01370.16 KLO14747.1 - 0.025 14.0 0.0 0.037 13.4 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.3 KLO14747.1 - 0.073 12.8 0.8 0.29 10.9 0.1 2.2 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase NAD_Gly3P_dh_N PF01210.18 KLO14747.1 - 0.11 12.2 0.2 0.51 10.0 0.0 2.0 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus 2-Hacid_dh_C PF02826.14 KLO14747.1 - 0.19 10.8 1.1 0.6 9.2 0.3 2.1 2 1 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain adh_short PF00106.20 KLO14748.1 - 7.5e-25 87.7 0.6 1.5e-24 86.8 0.4 1.5 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 KLO14748.1 - 4.7e-12 45.9 0.6 1.4e-11 44.4 0.3 1.7 2 0 0 2 2 2 1 KR domain adh_short_C2 PF13561.1 KLO14748.1 - 6.4e-11 42.4 0.4 8.4e-11 42.0 0.3 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase 3HCDH_N PF02737.13 KLO14748.1 - 0.00052 19.7 4.6 0.0024 17.5 0.7 2.9 3 1 0 3 3 3 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_10 PF13460.1 KLO14748.1 - 0.0027 17.7 0.5 0.0055 16.7 0.4 1.8 1 1 0 1 1 1 1 NADH(P)-binding F420_oxidored PF03807.12 KLO14748.1 - 0.0029 17.9 0.9 0.0046 17.3 0.1 1.7 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent Shikimate_DH PF01488.15 KLO14748.1 - 0.0034 17.4 0.2 0.0074 16.3 0.2 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase ApbA PF02558.11 KLO14748.1 - 0.0075 15.7 0.0 0.015 14.7 0.0 1.6 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Epimerase PF01370.16 KLO14748.1 - 0.021 14.2 0.1 0.037 13.4 0.1 1.6 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family THF_DHG_CYH_C PF02882.14 KLO14748.1 - 0.031 13.3 0.0 0.064 12.3 0.0 1.6 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Bacteriocin_IId PF09221.5 KLO14748.1 - 0.16 11.9 4.1 0.59 10.0 0.2 2.4 2 0 0 2 2 2 0 Bacteriocin class IId cyclical uberolysin-like Radical_SAM PF04055.16 KLO14749.1 - 5e-16 59.3 0.0 1.2e-15 58.1 0.0 1.7 1 1 0 1 1 1 1 Radical SAM superfamily Fer4_12 PF13353.1 KLO14749.1 - 1.7e-07 31.4 0.4 3.8e-07 30.3 0.1 1.7 2 0 0 2 2 2 1 4Fe-4S single cluster domain Fer4_14 PF13394.1 KLO14749.1 - 2.5e-06 27.4 0.2 8.7e-06 25.7 0.1 2.0 2 0 0 2 2 2 1 4Fe-4S single cluster domain Het-C PF07217.6 KLO14749.1 - 0.071 11.2 0.0 0.085 11.0 0.0 1.1 1 0 0 1 1 1 0 Heterokaryon incompatibility protein Het-C Peptidase_S28 PF05577.7 KLO14751.1 - 4.3e-54 183.7 0.0 9.1e-54 182.6 0.0 1.4 1 1 0 1 1 1 1 Serine carboxypeptidase S28 Pup_ligase PF03136.10 KLO14752.1 - 0.1 11.2 0.1 0.12 10.9 0.0 1.1 1 0 0 1 1 1 0 Pup-ligase protein Abhydrolase_3 PF07859.8 KLO14753.1 - 3.6e-20 72.4 0.0 6.9e-15 55.1 0.0 2.3 2 1 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KLO14753.1 - 1.1e-11 44.6 0.0 2.9e-11 43.3 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 KLO14753.1 - 1.2e-09 37.7 0.1 3e-06 26.6 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_6 PF12697.2 KLO14753.1 - 6.9e-07 29.3 0.0 1.3e-06 28.4 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family COesterase PF00135.23 KLO14753.1 - 9.3e-07 27.9 0.1 0.00018 20.3 0.0 2.4 3 0 0 3 3 3 2 Carboxylesterase family Chlorophyllase2 PF12740.2 KLO14753.1 - 0.00028 19.8 0.1 0.001 18.0 0.0 1.8 2 0 0 2 2 2 1 Chlorophyllase enzyme Chlorophyllase PF07224.6 KLO14753.1 - 0.0032 16.2 0.0 0.0055 15.5 0.0 1.3 1 0 0 1 1 1 1 Chlorophyllase Esterase PF00756.15 KLO14753.1 - 0.0074 15.7 0.0 0.12 11.7 0.0 2.3 1 1 0 1 1 1 1 Putative esterase Abhydrolase_2 PF02230.11 KLO14753.1 - 0.012 15.0 0.0 0.19 11.1 0.0 2.2 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase TPK_catalytic PF04263.11 KLO14753.1 - 0.014 15.0 0.0 0.077 12.5 0.0 2.0 2 0 0 2 2 2 0 Thiamin pyrophosphokinase, catalytic domain DLH PF01738.13 KLO14753.1 - 0.017 14.4 0.1 0.057 12.6 0.0 1.8 2 0 0 2 2 2 0 Dienelactone hydrolase family DUF2424 PF10340.4 KLO14753.1 - 0.096 11.3 0.0 0.14 10.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2424) Rad4 PF03835.10 KLO14754.1 - 2.1e-26 92.0 0.0 2.1e-26 92.0 0.0 2.3 3 0 0 3 3 3 1 Rad4 transglutaminase-like domain BHD_3 PF10405.4 KLO14754.1 - 5.4e-26 90.0 0.1 1.1e-25 89.1 0.0 1.5 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 3 BHD_1 PF10403.4 KLO14754.1 - 9.2e-19 66.7 0.1 2.2e-18 65.4 0.1 1.7 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 1 BHD_2 PF10404.4 KLO14754.1 - 9.3e-14 51.4 0.1 3.4e-13 49.6 0.0 2.1 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 2 Transglut_core PF01841.14 KLO14754.1 - 1.5e-06 28.3 0.0 0.0001 22.4 0.0 2.9 3 0 0 3 3 3 1 Transglutaminase-like superfamily GCD14 PF08704.5 KLO14755.1 - 1.1e-88 296.8 0.0 2.3e-87 292.6 0.0 2.0 1 1 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit Methyltransf_31 PF13847.1 KLO14755.1 - 6.7e-06 25.7 0.0 9.7e-06 25.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KLO14755.1 - 1e-05 25.5 0.1 1.9e-05 24.6 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 KLO14755.1 - 4.4e-05 23.1 0.0 7.6e-05 22.3 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MTS PF05175.9 KLO14755.1 - 0.00042 19.7 0.0 0.00072 18.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_18 PF12847.2 KLO14755.1 - 0.00049 20.6 0.0 0.00092 19.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_24 PF13578.1 KLO14755.1 - 0.00084 20.1 1.1 0.0021 18.8 0.1 2.1 2 1 0 2 2 2 1 Methyltransferase domain Fibrillarin PF01269.12 KLO14755.1 - 0.0051 15.7 0.0 0.0079 15.1 0.0 1.2 1 0 0 1 1 1 1 Fibrillarin Methyltransf_4 PF02390.12 KLO14755.1 - 0.0059 15.6 0.0 0.0097 14.9 0.0 1.2 1 0 0 1 1 1 1 Putative methyltransferase RrnaAD PF00398.15 KLO14755.1 - 0.012 14.7 0.0 0.018 14.0 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Methyltransf_12 PF08242.7 KLO14755.1 - 0.026 15.0 1.0 0.084 13.3 0.0 2.2 2 0 0 2 2 2 0 Methyltransferase domain PAS_3 PF08447.6 KLO14756.1 - 0.023 14.7 0.0 0.059 13.4 0.0 1.7 1 0 0 1 1 1 0 PAS fold PAS_9 PF13426.1 KLO14756.1 - 0.027 14.8 0.0 3.9 7.8 0.0 2.4 2 0 0 2 2 2 0 PAS domain Pkinase PF00069.20 KLO14757.1 - 1.6e-65 220.8 0.0 2.3e-65 220.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KLO14757.1 - 9.5e-36 123.1 0.0 7.9e-34 116.8 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 KLO14757.1 - 2.3e-05 23.5 0.0 0.00011 21.3 0.0 2.0 2 0 0 2 2 2 1 Kinase-like Seadorna_VP7 PF07387.6 KLO14757.1 - 0.022 13.5 0.1 0.04 12.7 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 DUF2235 PF09994.4 KLO14758.1 - 3.9e-73 246.2 0.0 5.2e-73 245.8 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) Abhydrolase_5 PF12695.2 KLO14758.1 - 0.018 14.8 0.0 0.049 13.3 0.0 1.8 1 1 0 1 1 1 0 Alpha/beta hydrolase family CN_hydrolase PF00795.17 KLO14759.1 - 1.8e-15 56.7 0.0 2.6e-15 56.2 0.0 1.2 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase ATS PF15445.1 KLO14759.1 - 0.13 11.2 0.2 0.18 10.8 0.1 1.1 1 0 0 1 1 1 0 acidic terminal segments, variant surface antigen of PfEMP1 Cullin PF00888.17 KLO14760.1 - 5.6e-47 160.5 0.0 5.9e-46 157.1 0.0 2.0 2 0 0 2 2 2 1 Cullin family APC2 PF08672.6 KLO14760.1 - 1.5e-09 37.9 0.0 6e-09 36.0 0.0 2.1 1 0 0 1 1 1 1 Anaphase promoting complex (APC) subunit 2 Alpha-amylase_C PF02806.13 KLO14760.1 - 0.021 14.9 0.0 0.051 13.7 0.0 1.6 1 0 0 1 1 1 0 Alpha amylase, C-terminal all-beta domain FeoC PF09012.5 KLO14760.1 - 0.03 14.0 0.0 0.077 12.7 0.0 1.6 1 0 0 1 1 1 0 FeoC like transcriptional regulator HTH_27 PF13463.1 KLO14760.1 - 0.047 14.0 0.0 0.16 12.3 0.0 2.0 2 0 0 2 2 2 0 Winged helix DNA-binding domain HSP20 PF00011.16 KLO14761.1 - 7.9e-15 54.5 0.0 1.9e-09 37.3 0.0 2.2 2 0 0 2 2 2 2 Hsp20/alpha crystallin family GvpH PF05455.6 KLO14761.1 - 0.031 13.8 0.2 0.15 11.6 0.0 1.9 1 1 1 2 2 2 0 GvpH Ribosomal_60s PF00428.14 KLO14761.1 - 0.038 14.3 2.7 0.043 14.2 1.2 1.5 1 1 0 1 1 1 0 60s Acidic ribosomal protein DUF1325 PF07039.6 KLO14762.1 - 3.8e-29 100.9 0.0 5.9e-29 100.3 0.0 1.3 1 0 0 1 1 1 1 SGF29 tudor-like domain TUDOR PF00567.19 KLO14762.1 - 0.14 12.0 0.0 0.27 11.0 0.0 1.5 1 0 0 1 1 1 0 Tudor domain DUF3921 PF13060.1 KLO14762.1 - 0.14 12.0 0.1 0.24 11.2 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3921) Translin PF01997.11 KLO14763.1 - 2.7e-45 154.4 0.0 3.2e-45 154.2 0.0 1.0 1 0 0 1 1 1 1 Translin family ATP-synt_D PF01813.12 KLO14763.1 - 0.099 12.1 0.0 13 5.3 0.0 2.1 2 0 0 2 2 2 0 ATP synthase subunit D SEN1_N PF12726.2 KLO14764.1 - 6.7e-99 331.9 1.9 8.6e-99 331.5 1.3 1.1 1 0 0 1 1 1 1 SEN1 N terminal AAA_11 PF13086.1 KLO14764.1 - 2.3e-68 230.3 1.0 2.3e-68 230.3 0.7 2.6 3 0 0 3 3 3 1 AAA domain AAA_12 PF13087.1 KLO14764.1 - 1.4e-59 200.8 0.0 2.7e-59 199.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 KLO14764.1 - 7.9e-11 41.5 0.4 2.7e-10 39.8 0.3 1.9 1 0 0 1 1 1 1 Part of AAA domain AAA_30 PF13604.1 KLO14764.1 - 1.5e-07 31.1 0.7 0.00033 20.3 0.0 2.5 2 0 0 2 2 2 2 AAA domain Viral_helicase1 PF01443.13 KLO14764.1 - 0.00089 18.8 0.8 1.1 8.7 0.0 3.5 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase AAA_25 PF13481.1 KLO14764.1 - 0.0021 17.5 0.0 0.0055 16.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain ResIII PF04851.10 KLO14764.1 - 0.0082 15.9 0.0 0.037 13.8 0.0 2.0 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DUF342 PF03961.8 KLO14764.1 - 0.015 13.7 2.5 0.025 12.9 1.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF342) IncA PF04156.9 KLO14764.1 - 7 6.1 10.3 2.6 7.5 4.2 2.3 2 0 0 2 2 2 0 IncA protein DivIC PF04977.10 KLO14764.1 - 7.3 6.1 7.6 27 4.3 4.6 2.5 1 1 1 2 2 2 0 Septum formation initiator CN_hydrolase PF00795.17 KLO14765.1 - 2.7e-16 59.4 0.0 3.8e-16 58.9 0.0 1.2 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase ATS PF15445.1 KLO14765.1 - 0.15 11.0 0.0 0.2 10.7 0.0 1.1 1 0 0 1 1 1 0 acidic terminal segments, variant surface antigen of PfEMP1 Prominin PF05478.6 KLO14766.1 - 0.14 9.6 0.0 0.19 9.2 0.0 1.1 1 0 0 1 1 1 0 Prominin C2 PF00168.25 KLO14768.1 - 3.1e-10 39.7 0.0 6.3e-10 38.7 0.0 1.5 1 0 0 1 1 1 1 C2 domain MHC_I_C PF06623.6 KLO14769.1 - 0.058 12.8 1.9 0.14 11.6 1.3 1.6 1 0 0 1 1 1 0 MHC_I C-terminus AMPKBI PF04739.10 KLO14770.1 - 9.6e-20 70.3 2.6 4.1e-19 68.3 1.8 2.1 1 1 0 1 1 1 1 5'-AMP-activated protein kinase beta subunit, interation domain A_deaminase PF00962.17 KLO14771.1 - 8.6e-111 370.0 0.3 1.1e-110 369.6 0.2 1.2 1 0 0 1 1 1 1 Adenosine/AMP deaminase MFS_1 PF07690.11 KLO14775.1 - 6.5e-10 38.2 8.0 8.1e-10 37.9 5.5 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KLO14775.1 - 2.2e-06 26.5 9.0 2.6e-06 26.3 4.9 1.4 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_2 PF13347.1 KLO14775.1 - 0.00092 17.7 1.5 0.0011 17.4 1.0 1.1 1 0 0 1 1 1 1 MFS/sugar transport protein Folate_carrier PF01770.13 KLO14775.1 - 0.1 11.0 0.0 0.21 10.0 0.0 1.4 1 1 0 1 1 1 0 Reduced folate carrier MFS_1 PF07690.11 KLO14776.1 - 6.3e-23 81.0 24.9 6.3e-23 81.0 17.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Aldolase_II PF00596.16 KLO14777.1 - 6.9e-37 126.8 0.0 7.9e-37 126.6 0.0 1.0 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain DUF4388 PF14332.1 KLO14777.1 - 0.14 11.9 0.0 0.21 11.4 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4388) HA2 PF04408.18 KLO14778.1 - 1.1e-21 76.7 1.4 2.9e-21 75.3 0.0 2.6 3 0 0 3 3 3 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.11 KLO14778.1 - 3.6e-15 55.8 0.0 8.7e-15 54.5 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.26 KLO14778.1 - 8.4e-14 51.2 0.2 1.2e-12 47.5 0.0 2.7 3 0 0 3 3 3 1 Helicase conserved C-terminal domain DEAD PF00270.24 KLO14778.1 - 9.4e-08 31.7 0.1 6.9e-07 28.9 0.0 2.2 1 1 1 2 2 2 1 DEAD/DEAH box helicase AAA_22 PF13401.1 KLO14778.1 - 5.5e-06 26.5 0.0 3.7e-05 23.8 0.0 2.4 3 0 0 3 3 3 1 AAA domain T2SE PF00437.15 KLO14778.1 - 0.0078 15.1 0.0 0.018 13.9 0.0 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein ResIII PF04851.10 KLO14778.1 - 0.0089 15.8 6.4 0.02 14.7 0.0 3.7 4 0 0 4 4 4 1 Type III restriction enzyme, res subunit KaiC PF06745.8 KLO14778.1 - 0.031 13.3 0.0 0.07 12.2 0.0 1.5 1 0 0 1 1 1 0 KaiC AAA_23 PF13476.1 KLO14778.1 - 0.085 13.1 0.0 0.085 13.1 0.0 3.2 4 0 0 4 4 4 0 AAA domain AAA_19 PF13245.1 KLO14778.1 - 0.11 12.2 0.0 0.31 10.8 0.0 1.8 1 0 0 1 1 1 0 Part of AAA domain UQ_con PF00179.21 KLO14782.1 - 1.3e-10 40.8 0.0 2.4e-10 39.9 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme tRNA_int_end_N2 PF12928.2 KLO14783.1 - 3.3e-18 64.9 0.0 5.3e-18 64.2 0.0 1.3 1 0 0 1 1 1 1 tRNA-splicing endonuclease subunit sen54 N-term tRNA_int_endo_N PF02778.9 KLO14783.1 - 0.046 13.2 0.0 0.091 12.3 0.0 1.4 1 0 0 1 1 1 0 tRNA intron endonuclease, N-terminal domain F-box-like PF12937.2 KLO14784.1 - 9.7e-11 41.2 0.5 9.7e-11 41.2 0.3 2.1 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 KLO14784.1 - 0.00011 21.7 0.1 0.00038 20.0 0.1 2.0 1 0 0 1 1 1 1 F-box domain DUF2905 PF11146.3 KLO14784.1 - 0.023 14.6 0.0 0.07 13.0 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2905) Tol_Tol_Ttg2 PF05494.7 KLO14784.1 - 0.17 11.4 0.0 6.1 6.3 0.0 2.2 2 0 0 2 2 2 0 Toluene tolerance, Ttg2 4HBT_3 PF13622.1 KLO14787.1 - 2.1e-25 89.9 0.1 6.7e-18 65.3 0.0 2.0 2 0 0 2 2 2 2 Thioesterase-like superfamily COP23 PF14218.1 KLO14787.1 - 0.065 12.7 0.0 0.16 11.5 0.0 1.6 1 0 0 1 1 1 0 Circadian oscillating protein COP23 Asp PF00026.18 KLO14788.1 - 4.3e-47 160.9 12.5 1e-46 159.6 8.6 1.6 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 KLO14788.1 - 4e-06 26.8 4.8 0.00022 21.1 2.0 3.2 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 KLO14788.1 - 0.0021 18.5 6.2 0.051 14.0 1.2 2.7 2 0 0 2 2 2 2 Aspartyl protease ABC2_membrane PF01061.19 KLO14790.1 - 1.3e-32 112.6 19.1 1.3e-32 112.6 13.2 1.6 2 0 0 2 2 2 1 ABC-2 type transporter ABC_tran PF00005.22 KLO14790.1 - 1.4e-21 77.2 0.1 2.2e-21 76.6 0.1 1.3 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 KLO14790.1 - 1.6e-08 34.9 0.0 2.4e-06 27.7 0.0 2.3 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 KLO14790.1 - 0.00039 20.4 0.1 0.00067 19.6 0.1 1.4 1 0 0 1 1 1 1 AAA ATPase domain DUF258 PF03193.11 KLO14790.1 - 0.0019 17.4 0.1 0.003 16.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_22 PF13401.1 KLO14790.1 - 0.0024 18.0 0.0 0.0059 16.7 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 KLO14790.1 - 0.0035 18.1 0.0 0.0078 17.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.1 KLO14790.1 - 0.0042 16.5 0.2 0.018 14.5 0.1 2.1 2 0 0 2 2 2 1 P-loop containing region of AAA domain ABC2_membrane_3 PF12698.2 KLO14790.1 - 0.0079 15.2 22.1 0.018 14.1 15.0 1.7 1 1 0 1 1 1 1 ABC-2 family transporter protein AAA_15 PF13175.1 KLO14790.1 - 0.0088 15.1 0.0 0.48 9.4 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain SbcCD_C PF13558.1 KLO14790.1 - 0.019 14.8 0.0 0.062 13.2 0.0 2.0 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_18 PF13238.1 KLO14790.1 - 0.021 15.1 0.0 0.04 14.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain SMC_N PF02463.14 KLO14790.1 - 0.022 13.9 0.1 0.91 8.7 0.1 2.2 1 1 0 1 1 1 0 RecF/RecN/SMC N terminal domain AAA PF00004.24 KLO14790.1 - 0.025 14.7 0.1 0.42 10.8 0.1 2.4 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.10 KLO14790.1 - 0.029 13.0 0.0 0.04 12.6 0.0 1.2 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein AAA_33 PF13671.1 KLO14790.1 - 0.029 14.2 0.0 0.054 13.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.1 KLO14790.1 - 0.13 11.6 0.1 21 4.4 0.0 2.6 3 0 0 3 3 3 0 AAA domain Fungal_trans PF04082.13 KLO14791.1 - 8.7e-20 70.6 0.0 2.4e-19 69.2 0.2 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KLO14791.1 - 4.1e-05 23.3 8.2 7.1e-05 22.6 5.7 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pkinase PF00069.20 KLO14792.1 - 7.6e-06 25.2 0.0 2.2e-05 23.7 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain APH PF01636.18 KLO14792.1 - 0.0016 18.2 0.0 0.0029 17.3 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_Tyr PF07714.12 KLO14792.1 - 0.1 11.6 0.0 0.18 10.8 0.0 1.3 1 0 0 1 1 1 0 Protein tyrosine kinase Glyco_hydro_10 PF00331.15 KLO14793.1 - 1.1e-90 303.9 0.0 1.3e-90 303.6 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 Peroxin-22 PF12827.2 KLO14793.1 - 0.14 11.8 0.0 0.27 10.9 0.0 1.4 1 0 0 1 1 1 0 Peroxisomal biogenesis protein family Glyco_transf_28 PF03033.15 KLO14794.1 - 8.1e-24 83.9 0.0 1.8e-23 82.8 0.0 1.6 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain UDPGT PF00201.13 KLO14794.1 - 3.7e-09 35.6 0.0 1e-08 34.2 0.0 1.7 1 1 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase PH PF00169.24 KLO14794.1 - 0.00047 20.3 0.0 0.025 14.7 0.0 3.1 3 0 0 3 3 3 1 PH domain PH_BEACH PF14844.1 KLO14794.1 - 0.0068 16.2 0.0 0.057 13.2 0.0 2.3 2 0 0 2 2 2 1 PH domain associated with Beige/BEACH Dynein_light PF01221.13 KLO14795.1 - 3.7e-27 94.1 1.4 5e-27 93.7 1.0 1.1 1 0 0 1 1 1 1 Dynein light chain type 1 3HCDH_N PF02737.13 KLO14796.1 - 2.3e-47 160.9 1.8 9.5e-46 155.7 0.4 2.5 2 1 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.17 KLO14796.1 - 8.9e-17 61.2 0.6 9e-14 51.6 0.2 3.8 2 2 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain NAD_binding_2 PF03446.10 KLO14796.1 - 0.0015 18.4 0.1 0.011 15.5 0.0 2.3 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase XdhC_C PF13478.1 KLO14796.1 - 0.0023 18.2 0.0 0.005 17.1 0.0 1.6 1 0 0 1 1 1 1 XdhC Rossmann domain DAO PF01266.19 KLO14796.1 - 0.0023 16.9 0.1 0.0042 16.0 0.1 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 KLO14796.1 - 0.0042 17.4 0.1 0.0096 16.3 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.16 KLO14796.1 - 0.0049 16.4 0.0 0.012 15.2 0.0 1.6 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_8 PF13450.1 KLO14796.1 - 0.016 15.2 0.2 0.055 13.4 0.2 1.9 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 KLO14796.1 - 0.018 14.9 0.0 0.033 14.0 0.0 1.6 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase UDPG_MGDP_dh_N PF03721.9 KLO14796.1 - 0.022 14.1 0.0 0.044 13.1 0.0 1.5 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 2-Hacid_dh_C PF02826.14 KLO14796.1 - 0.1 11.7 0.0 0.2 10.8 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DFP PF04127.10 KLO14796.1 - 0.22 11.0 6.9 0.26 10.8 0.2 3.1 1 1 2 3 3 3 0 DNA / pantothenate metabolism flavoprotein DUF1673 PF07895.6 KLO14797.1 - 0.35 10.3 6.2 0.6 9.6 4.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1673) Aldo_ket_red PF00248.16 KLO14798.1 - 2.2e-43 148.1 0.3 9.2e-30 103.4 0.0 2.1 1 1 1 2 2 2 2 Aldo/keto reductase family WD40 PF00400.27 KLO14801.1 - 1e-35 120.3 0.3 1.2e-08 34.5 0.0 6.3 7 0 0 7 7 7 4 WD domain, G-beta repeat Nup160 PF11715.3 KLO14801.1 - 4.7e-05 21.7 1.4 0.00059 18.1 0.1 2.7 2 1 1 3 3 3 1 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.11 KLO14801.1 - 0.00016 20.1 0.0 0.00026 19.4 0.0 1.4 1 0 0 1 1 1 1 Cytochrome D1 heme domain Coatomer_WDAD PF04053.9 KLO14801.1 - 0.00028 19.8 0.1 0.37 9.5 0.0 2.4 1 1 1 2 2 2 2 Coatomer WD associated region eIF2A PF08662.6 KLO14801.1 - 0.00039 20.1 0.8 0.087 12.5 0.0 3.1 1 1 3 4 4 4 2 Eukaryotic translation initiation factor eIF2A Nucleoporin_N PF08801.6 KLO14801.1 - 0.00088 18.1 0.1 0.25 10.0 0.1 2.3 1 1 1 2 2 2 2 Nup133 N terminal like Gmad1 PF10647.4 KLO14801.1 - 0.0012 18.3 0.3 0.026 13.9 0.1 2.2 1 1 1 2 2 2 1 Lipoprotein LpqB beta-propeller domain Ribosomal_S19e PF01090.14 KLO14802.1 - 3.7e-56 188.4 0.1 4.3e-56 188.2 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S19e Brevenin PF03032.10 KLO14802.1 - 7.1 6.5 9.3 13 5.7 6.4 1.5 1 0 0 1 1 1 0 Brevenin/esculentin/gaegurin/rugosin family Ribonuc_red_lgC PF02867.10 KLO14804.1 - 3.1e-211 702.6 0.0 4e-211 702.2 0.0 1.1 1 0 0 1 1 1 1 Ribonucleotide reductase, barrel domain Ribonuc_red_lgN PF00317.16 KLO14804.1 - 1.4e-24 85.6 0.1 3.2e-24 84.5 0.0 1.6 1 0 0 1 1 1 1 Ribonucleotide reductase, all-alpha domain ATP-cone PF03477.11 KLO14804.1 - 3.2e-14 53.1 0.1 1.1e-13 51.4 0.0 2.0 1 0 0 1 1 1 1 ATP cone domain Cullin PF00888.17 KLO14805.1 - 2.4e-188 627.3 8.3 3.5e-188 626.8 5.7 1.2 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.4 KLO14805.1 - 2.2e-28 97.8 3.3 2.2e-28 97.8 2.3 2.2 2 0 0 2 2 2 1 Cullin protein neddylation domain DUF1727 PF08353.5 KLO14805.1 - 0.013 15.0 0.0 0.068 12.7 0.0 2.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1727) WGG PF10273.4 KLO14805.1 - 0.36 10.9 4.3 15 5.7 0.0 4.0 4 0 0 4 4 4 0 Pre-rRNA-processing protein TSR2 RE_XamI PF09572.5 KLO14806.1 - 0.065 12.6 0.0 0.1 12.0 0.0 1.2 1 0 0 1 1 1 0 XamI restriction endonuclease Pox_A_type_inc PF04508.7 KLO14806.1 - 0.21 11.4 1.8 12 5.9 0.1 2.4 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat DUF2478 PF10649.4 KLO14807.1 - 0.027 13.8 0.1 0.028 13.7 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2478) KAT11 PF08214.6 KLO14808.1 - 1e-38 133.3 0.0 1.4e-38 132.8 0.0 1.2 1 0 0 1 1 1 1 Histone acetylation protein zf-MYND PF01753.13 KLO14809.1 - 1.3e-08 34.5 12.6 1.3e-08 34.5 8.7 2.6 2 0 0 2 2 2 1 MYND finger Rhodopsin_N PF10413.4 KLO14809.1 - 0.021 14.4 0.3 0.047 13.3 0.2 1.6 1 0 0 1 1 1 0 Amino terminal of the G-protein receptor rhodopsin zf-CCCH_2 PF14608.1 KLO14809.1 - 0.4 10.7 4.4 2 8.5 0.7 3.2 2 1 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type zf-Mss51 PF13824.1 KLO14809.1 - 3.2 7.6 12.9 0.56 10.1 4.0 2.9 3 0 0 3 3 3 0 Zinc-finger of mitochondrial splicing suppressor 51 MRP-L20 PF12824.2 KLO14810.1 - 4.3e-25 88.5 4.4 5.1e-25 88.3 3.1 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal protein subunit L20 SDA1 PF05285.7 KLO14810.1 - 0.024 13.9 0.1 0.029 13.6 0.1 1.2 1 0 0 1 1 1 0 SDA1 Metal_resist PF13801.1 KLO14810.1 - 0.27 11.2 5.0 0.27 11.2 0.3 2.4 2 1 1 3 3 3 0 Heavy-metal resistance ICL PF00463.16 KLO14811.1 - 5e-244 810.3 0.0 5.7e-244 810.1 0.0 1.0 1 0 0 1 1 1 1 Isocitrate lyase family PEP_mutase PF13714.1 KLO14811.1 - 4.3e-09 35.9 0.0 6.7e-09 35.3 0.0 1.3 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase TrbL PF04610.9 KLO14811.1 - 0.26 10.9 1.1 0.44 10.2 0.0 1.9 2 0 0 2 2 2 0 TrbL/VirB6 plasmid conjugal transfer protein NuA4 PF09340.5 KLO14812.1 - 1.6e-21 75.6 1.9 1.6e-21 75.6 1.3 1.6 2 0 0 2 2 2 1 Histone acetyltransferase subunit NuA4 K_channel_TID PF07941.6 KLO14812.1 - 1.5 9.1 5.3 0.21 11.8 0.3 2.2 2 0 0 2 2 2 0 Potassium channel Kv1.4 tandem inactivation domain SET PF00856.23 KLO14813.1 - 1.5e-08 35.1 0.1 4.1e-08 33.6 0.1 1.8 1 1 0 1 1 1 1 SET domain dCMP_cyt_deam_1 PF00383.17 KLO14813.1 - 3.8e-07 29.7 0.0 6.8e-07 28.8 0.0 1.5 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region HET PF06985.6 KLO14814.1 - 2.9e-09 37.1 4.5 0.0018 18.4 0.0 3.4 3 0 0 3 3 3 3 Heterokaryon incompatibility protein (HET) Glycos_transf_4 PF00953.16 KLO14815.1 - 1.8e-30 105.8 10.0 1.8e-30 105.8 6.9 2.1 3 0 0 3 3 3 1 Glycosyl transferase family 4 DUF3421 PF11901.3 KLO14816.1 - 9.5e-13 47.9 0.1 1.9e-08 34.0 0.0 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF3421) HET PF06985.6 KLO14817.1 - 2.2e-06 27.8 5.1 0.019 15.1 0.0 4.1 4 0 0 4 4 4 3 Heterokaryon incompatibility protein (HET) HET PF06985.6 KLO14820.1 - 0.00037 20.6 1.8 0.0012 18.9 0.1 2.2 2 0 0 2 2 2 1 Heterokaryon incompatibility protein (HET) F-box-like PF12937.2 KLO14821.1 - 1.5e-05 24.6 0.2 4.5e-05 23.0 0.1 1.9 1 1 0 1 1 1 1 F-box-like Ubie_methyltran PF01209.13 KLO14822.1 - 1.3e-80 269.8 0.0 1.6e-80 269.5 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_11 PF08241.7 KLO14822.1 - 1.7e-12 47.6 0.0 2.8e-12 46.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KLO14822.1 - 6e-12 45.5 0.0 9.5e-12 44.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KLO14822.1 - 7.1e-12 45.1 0.0 1e-11 44.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KLO14822.1 - 1.3e-11 44.7 0.0 2.5e-11 43.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KLO14822.1 - 2.4e-11 43.9 0.0 4.1e-11 43.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KLO14822.1 - 3e-07 30.9 0.0 5.2e-07 30.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KLO14822.1 - 6.6e-05 22.9 0.0 0.00018 21.5 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Glyco_transf_90 PF05686.7 KLO14822.1 - 0.16 10.6 0.0 0.21 10.2 0.0 1.1 1 0 0 1 1 1 0 Glycosyl transferase family 90 Fcf2 PF08698.6 KLO14823.1 - 1.2e-19 70.1 0.0 2.5e-19 69.1 0.0 1.6 1 1 0 1 1 1 1 Fcf2 pre-rRNA processing NAD_binding_10 PF13460.1 KLO14824.1 - 5.2e-22 78.7 0.0 7.6e-22 78.1 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 KLO14824.1 - 3.1e-11 42.9 0.0 5.7e-11 42.1 0.0 1.4 2 0 0 2 2 2 1 NmrA-like family RmlD_sub_bind PF04321.12 KLO14824.1 - 5.3e-11 41.9 0.0 5.7e-09 35.2 0.0 2.4 1 1 0 1 1 1 1 RmlD substrate binding domain Epimerase PF01370.16 KLO14824.1 - 9e-11 41.6 0.1 3.1e-09 36.6 0.1 2.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 KLO14824.1 - 8.7e-10 37.7 0.0 1.2e-08 34.0 0.0 2.0 1 1 1 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 KLO14824.1 - 4.2e-06 25.8 0.2 0.014 14.3 0.0 2.6 2 1 0 2 2 2 2 Male sterility protein Polysacc_synt_2 PF02719.10 KLO14824.1 - 0.0076 15.1 0.0 0.015 14.2 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Saccharop_dh PF03435.13 KLO14824.1 - 0.023 13.6 0.0 0.037 13.0 0.0 1.3 1 0 0 1 1 1 0 Saccharopine dehydrogenase adh_short PF00106.20 KLO14824.1 - 0.12 12.3 0.0 0.22 11.3 0.0 1.5 1 1 0 1 1 1 0 short chain dehydrogenase DUF2462 PF09495.5 KLO14825.1 - 1.9e-14 54.1 11.0 2.5e-14 53.7 7.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2462) Glyco_hydro_35 PF01301.14 KLO14827.1 - 5e-75 252.8 0.0 6.6e-75 252.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 BetaGal_dom4_5 PF13364.1 KLO14827.1 - 6.7e-47 158.3 9.7 9.5e-25 87.0 0.2 3.7 3 0 0 3 3 3 2 Beta-galactosidase jelly roll domain BetaGal_dom2 PF10435.4 KLO14827.1 - 6.6e-37 126.6 6.4 9.9e-37 126.0 4.0 1.6 1 1 0 1 1 1 1 Beta-galactosidase, domain 2 BetaGal_dom3 PF13363.1 KLO14827.1 - 1.6e-20 72.2 0.1 4.6e-20 70.7 0.1 1.8 1 0 0 1 1 1 1 Beta-galactosidase, domain 3 Amidohydro_2 PF04909.9 KLO14827.1 - 0.027 14.0 0.1 0.2 11.1 0.0 2.2 2 0 0 2 2 2 0 Amidohydrolase Fic PF02661.13 KLO14829.1 - 5e-08 33.5 0.0 8e-08 32.8 0.0 1.5 1 0 0 1 1 1 1 Fic/DOC family Sas10 PF09368.5 KLO14830.1 - 1.3e-22 79.7 3.3 1.3e-22 79.7 2.3 3.4 3 0 0 3 3 3 1 Sas10 C-terminal domain Sas10_Utp3 PF04000.10 KLO14830.1 - 8.8e-07 29.0 0.3 8.8e-07 29.0 0.2 2.4 2 0 0 2 2 2 1 Sas10/Utp3/C1D family Nop14 PF04147.7 KLO14830.1 - 0.0021 16.0 0.7 0.0021 16.0 0.5 3.1 2 1 1 3 3 3 1 Nop14-like family Pex14_N PF04695.8 KLO14830.1 - 2 8.4 13.5 2.9 7.9 2.4 2.9 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region EPL1 PF10513.4 KLO14831.1 - 3.5e-18 66.3 0.3 1.3e-17 64.4 0.0 2.2 2 0 0 2 2 2 1 Enhancer of polycomb-like TPP_enzyme_N PF02776.13 KLO14832.1 - 2.6e-35 121.4 0.0 3.9e-35 120.8 0.0 1.3 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.17 KLO14832.1 - 1.4e-20 73.4 0.0 3.6e-20 72.1 0.0 1.7 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.16 KLO14832.1 - 7.5e-13 48.3 0.0 4.1e-12 45.9 0.0 2.2 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Pap_E4 PF02711.9 KLO14833.1 - 0.058 14.2 0.1 0.11 13.3 0.1 1.4 1 0 0 1 1 1 0 E4 protein Tim54 PF11711.3 KLO14834.1 - 0.0039 15.8 0.5 0.005 15.4 0.4 1.1 1 0 0 1 1 1 1 Inner membrane protein import complex subunit Tim54 DUF2457 PF10446.4 KLO14834.1 - 0.0063 15.2 8.9 0.008 14.9 6.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2457) CDC45 PF02724.9 KLO14834.1 - 0.025 12.6 1.9 0.027 12.5 1.3 1.1 1 0 0 1 1 1 0 CDC45-like protein CENP-B_dimeris PF09026.5 KLO14834.1 - 0.03 14.5 15.2 0.048 13.8 10.6 1.2 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Radial_spoke PF04712.7 KLO14834.1 - 0.033 12.9 2.2 0.04 12.6 1.5 1.1 1 0 0 1 1 1 0 Radial spokehead-like protein FAM177 PF14774.1 KLO14834.1 - 0.041 13.7 2.2 0.065 13.1 1.6 1.3 1 0 0 1 1 1 0 FAM177 family Myc_N PF01056.13 KLO14834.1 - 0.055 12.6 4.0 0.071 12.2 2.8 1.2 1 0 0 1 1 1 0 Myc amino-terminal region Sigma70_ner PF04546.8 KLO14834.1 - 0.15 11.6 7.6 0.21 11.1 5.3 1.2 1 0 0 1 1 1 0 Sigma-70, non-essential region TRAP_alpha PF03896.11 KLO14834.1 - 0.2 10.6 2.2 0.24 10.3 1.5 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit DUF4484 PF14831.1 KLO14834.1 - 0.27 11.3 3.8 0.4 10.7 2.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4484) PBP1_TM PF14812.1 KLO14834.1 - 0.3 11.4 9.8 0.51 10.6 6.8 1.3 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Nucleoplasmin PF03066.10 KLO14834.1 - 0.4 10.2 14.3 0.63 9.5 9.9 1.2 1 0 0 1 1 1 0 Nucleoplasmin FAM176 PF14851.1 KLO14834.1 - 0.68 9.5 4.0 0.98 9.0 2.7 1.2 1 0 0 1 1 1 0 FAM176 family ANAPC15 PF15243.1 KLO14834.1 - 0.78 9.8 13.4 1.3 9.1 9.3 1.3 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 15 RXT2_N PF08595.6 KLO14834.1 - 1.5 8.5 8.1 2.5 7.9 5.6 1.3 1 0 0 1 1 1 0 RXT2-like, N-terminal NOA36 PF06524.7 KLO14834.1 - 3.1 6.9 9.9 4.4 6.4 6.8 1.1 1 0 0 1 1 1 0 NOA36 protein VID27 PF08553.5 KLO14834.1 - 3.3 5.8 6.3 4.4 5.4 4.4 1.1 1 0 0 1 1 1 0 VID27 cytoplasmic protein Nop14 PF04147.7 KLO14834.1 - 4 5.2 13.2 5.2 4.8 9.1 1.0 1 0 0 1 1 1 0 Nop14-like family Daxx PF03344.10 KLO14834.1 - 5 5.4 11.9 6.4 5.1 8.3 1.1 1 0 0 1 1 1 0 Daxx Family RNA_pol_3_Rpc31 PF11705.3 KLO14834.1 - 8.1 6.3 15.1 12 5.7 10.5 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 Sigma70_ner PF04546.8 KLO14835.1 - 0.39 10.2 3.0 0.5 9.9 2.1 1.1 1 0 0 1 1 1 0 Sigma-70, non-essential region Tom22 PF04281.8 KLO14835.1 - 0.43 10.1 3.1 0.61 9.6 2.1 1.2 1 0 0 1 1 1 0 Mitochondrial import receptor subunit Tom22 PBP1_TM PF14812.1 KLO14835.1 - 1.3 9.4 8.0 2.1 8.6 5.6 1.3 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Nucleoplasmin PF03066.10 KLO14835.1 - 1.8 8.0 7.6 2.5 7.5 5.3 1.2 1 0 0 1 1 1 0 Nucleoplasmin DUF2457 PF10446.4 KLO14835.1 - 2.5 6.7 8.5 3.2 6.3 5.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Nucleoplasmin PF03066.10 KLO14836.1 - 0.038 13.5 0.1 0.044 13.3 0.1 1.2 1 0 0 1 1 1 0 Nucleoplasmin Myc_N PF01056.13 KLO14836.1 - 0.099 11.7 1.8 0.14 11.2 1.2 1.2 1 0 0 1 1 1 0 Myc amino-terminal region CENP-B_dimeris PF09026.5 KLO14836.1 - 0.11 12.7 4.1 0.17 12.1 2.8 1.3 1 0 0 1 1 1 0 Centromere protein B dimerisation domain PBP1_TM PF14812.1 KLO14836.1 - 0.84 9.9 3.7 1.5 9.1 2.6 1.4 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal RXT2_N PF08595.6 KLO14839.1 - 0.099 12.4 0.2 0.14 11.9 0.2 1.2 1 0 0 1 1 1 0 RXT2-like, N-terminal BBIP10 PF14777.1 KLO14841.1 - 0.049 13.0 0.0 0.081 12.3 0.0 1.4 1 0 0 1 1 1 0 Cilia BBSome complex subunit 10 Rho_N PF07498.7 KLO14841.1 - 0.082 12.6 0.1 1.8 8.3 0.0 2.3 2 0 0 2 2 2 0 Rho termination factor, N-terminal domain IF2_N PF04760.10 KLO14841.1 - 0.11 12.1 0.0 0.35 10.5 0.0 1.8 2 0 0 2 2 2 0 Translation initiation factor IF-2, N-terminal region MOZ_SAS PF01853.13 KLO14843.1 - 3e-83 277.7 0.4 4.4e-83 277.1 0.3 1.2 1 0 0 1 1 1 1 MOZ/SAS family Tudor-knot PF11717.3 KLO14843.1 - 6.3e-16 57.8 0.1 1.4e-15 56.7 0.1 1.6 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain HTH_Mga PF08280.6 KLO14843.1 - 0.00013 21.6 0.3 0.00028 20.5 0.2 1.5 1 0 0 1 1 1 1 M protein trans-acting positive regulator (MGA) HTH domain HTH_11 PF08279.7 KLO14843.1 - 0.03 13.9 0.1 0.079 12.6 0.1 1.7 1 0 0 1 1 1 0 HTH domain Acetyltransf_1 PF00583.19 KLO14843.1 - 0.043 13.8 0.0 0.091 12.8 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family zf-C2H2_4 PF13894.1 KLO14843.1 - 0.29 11.5 2.0 0.98 9.9 1.4 1.9 1 0 0 1 1 1 0 C2H2-type zinc finger zf-C2H2 PF00096.21 KLO14843.1 - 1.1 9.7 5.7 0.19 12.1 1.1 1.9 2 0 0 2 2 2 0 Zinc finger, C2H2 type RepA_C PF04796.7 KLO14844.1 - 0.097 12.2 0.0 0.11 12.0 0.0 1.1 1 0 0 1 1 1 0 Plasmid encoded RepA protein DDE_1 PF03184.14 KLO14845.1 - 8.1e-31 106.8 0.0 9.9e-31 106.5 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_3 PF13358.1 KLO14845.1 - 0.00014 21.6 0.0 0.0011 18.7 0.0 2.1 1 1 1 2 2 2 2 DDE superfamily endonuclease FA_desaturase PF00487.19 KLO14847.1 - 5.9e-23 81.6 23.2 5.9e-23 81.6 16.1 2.0 2 1 0 2 2 2 1 Fatty acid desaturase DUF3474 PF11960.3 KLO14847.1 - 0.091 12.7 0.0 0.16 12.0 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3474) 7tm_7 PF08395.7 KLO14847.1 - 2.6 6.9 5.3 0.53 9.2 0.2 1.9 2 0 0 2 2 2 0 7tm Chemosensory receptor NAD_binding_10 PF13460.1 KLO14848.1 - 2.8e-07 30.6 0.0 4e-07 30.2 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding D123 PF07065.9 KLO14849.1 - 9.2e-76 254.7 0.0 1.2e-75 254.4 0.0 1.1 1 0 0 1 1 1 1 D123 PBP_GOBP PF01395.17 KLO14849.1 - 0.026 14.1 0.0 0.069 12.7 0.0 1.7 2 0 0 2 2 2 0 PBP/GOBP family DUF4343 PF14243.1 KLO14849.1 - 0.047 13.5 0.0 0.084 12.7 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4343) AAL_decarboxy PF03306.8 KLO14849.1 - 0.13 11.2 0.0 0.25 10.3 0.0 1.4 1 1 0 1 1 1 0 Alpha-acetolactate decarboxylase Alliinase_C PF04864.8 KLO14852.1 - 0.068 11.8 0.2 0.087 11.4 0.2 1.1 1 0 0 1 1 1 0 Allinase DDE_1 PF03184.14 KLO14856.1 - 2.8e-29 101.8 0.0 3.5e-29 101.5 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_3 PF13358.1 KLO14856.1 - 1e-07 31.8 0.0 1.5e-07 31.2 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease DEAD PF00270.24 KLO14857.1 - 0.00088 18.8 0.0 0.00096 18.6 0.0 1.1 1 0 0 1 1 1 1 DEAD/DEAH box helicase IncA PF04156.9 KLO14858.1 - 0.079 12.5 0.3 0.14 11.7 0.2 1.3 1 0 0 1 1 1 0 IncA protein Ctr PF04145.10 KLO14858.1 - 0.13 12.2 1.7 0.27 11.2 0.0 2.1 2 0 0 2 2 2 0 Ctr copper transporter family Fungal_trans PF04082.13 KLO14859.1 - 1.5e-19 69.8 0.3 2.6e-19 69.1 0.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KLO14859.1 - 1e-06 28.5 11.8 1.8e-06 27.7 8.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain WD40 PF00400.27 KLO14860.1 - 1e-05 25.2 6.1 0.001 18.8 0.1 4.1 4 0 0 4 4 4 3 WD domain, G-beta repeat ING PF12998.2 KLO14861.1 - 9.2e-11 41.9 0.3 3.4e-10 40.1 0.2 1.8 1 1 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.24 KLO14861.1 - 1.5e-08 34.1 8.8 2.4e-08 33.5 6.1 1.3 1 0 0 1 1 1 1 PHD-finger zf-HC5HC2H PF13771.1 KLO14861.1 - 1 9.5 4.4 3 8.0 3.0 1.8 1 1 0 1 1 1 0 PHD-like zinc-binding domain GalP_UDP_transf PF01087.17 KLO14862.1 - 1.9e-60 204.0 0.0 3e-60 203.3 0.0 1.2 1 0 0 1 1 1 1 Galactose-1-phosphate uridyl transferase, N-terminal domain GalP_UDP_tr_C PF02744.12 KLO14862.1 - 2.4e-44 150.8 0.0 4.9e-44 149.8 0.0 1.5 1 0 0 1 1 1 1 Galactose-1-phosphate uridyl transferase, C-terminal domain HIT PF01230.18 KLO14862.1 - 0.00051 20.5 0.0 0.0019 18.7 0.0 2.0 2 1 0 2 2 2 1 HIT domain DcpS_C PF11969.3 KLO14862.1 - 0.016 15.4 0.1 0.055 13.6 0.0 1.9 1 1 0 1 1 1 0 Scavenger mRNA decapping enzyme C-term binding Sel1 PF08238.7 KLO14863.1 - 3.2e-50 167.4 18.0 3.3e-08 33.9 0.0 7.8 7 0 0 7 7 7 7 Sel1 repeat TPR_14 PF13428.1 KLO14863.1 - 0.011 16.2 11.7 1.4 9.7 0.5 6.3 6 1 1 7 7 7 0 Tetratricopeptide repeat TPR_6 PF13174.1 KLO14863.1 - 0.033 14.6 0.1 17 6.1 0.0 3.7 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF1387 PF07139.6 KLO14863.1 - 1 8.8 4.0 1.3 8.5 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1387) RNA12 PF10443.4 KLO14864.1 - 2.6e-120 401.8 0.7 8.1e-120 400.2 0.5 1.7 1 1 0 1 1 1 1 RNA12 protein AAA_16 PF13191.1 KLO14864.1 - 1.5e-06 28.3 0.6 4.8e-06 26.6 0.2 2.2 1 1 0 1 1 1 1 AAA ATPase domain Arch_ATPase PF01637.13 KLO14864.1 - 4.6e-05 23.2 0.0 0.00032 20.4 0.0 2.3 1 1 0 1 1 1 1 Archaeal ATPase AAA PF00004.24 KLO14864.1 - 0.00023 21.3 0.0 0.00048 20.3 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 KLO14864.1 - 0.00084 19.4 0.0 0.0035 17.4 0.0 2.1 1 1 0 1 1 1 1 AAA domain RraB PF06877.6 KLO14864.1 - 0.016 15.8 0.1 0.91 10.2 0.0 3.0 3 0 0 3 3 3 0 Regulator of ribonuclease activity B AAA_19 PF13245.1 KLO14864.1 - 0.02 14.6 0.0 1.2 8.9 0.0 2.6 2 0 0 2 2 2 0 Part of AAA domain AAA_33 PF13671.1 KLO14864.1 - 0.02 14.7 0.2 0.094 12.5 0.0 2.3 2 1 0 2 2 2 0 AAA domain FtsK_SpoIIIE PF01580.13 KLO14864.1 - 0.052 13.0 0.0 0.69 9.3 0.0 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family RNA_helicase PF00910.17 KLO14864.1 - 0.078 13.1 0.0 0.17 12.0 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AAA_14 PF13173.1 KLO14864.1 - 0.12 12.2 0.0 0.33 10.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain SMC_N PF02463.14 KLO14864.1 - 0.14 11.3 0.0 0.4 9.8 0.0 1.7 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 KLO14864.1 - 0.83 9.9 0.0 0.83 9.9 0.0 2.8 3 1 0 3 3 3 0 AAA domain Nucleoporin_FG PF13634.1 KLO14865.1 - 0.0085 16.3 40.2 0.0085 16.3 27.9 7.3 2 2 2 4 4 4 1 Nucleoporin FG repeat region F-box-like PF12937.2 KLO14866.1 - 1.4e-07 31.1 0.3 3.7e-07 29.7 0.2 1.8 1 0 0 1 1 1 1 F-box-like HMA PF00403.21 KLO14867.1 - 1.7e-10 40.8 0.7 2.9e-10 40.1 0.5 1.4 1 1 0 1 1 1 1 Heavy-metal-associated domain Coiled PF05710.7 KLO14867.1 - 0.081 13.3 0.6 0.17 12.4 0.4 1.6 1 1 0 1 1 1 0 Coiled coil Lipid_bd PF12888.2 KLO14867.1 - 0.087 12.6 0.1 0.12 12.2 0.1 1.3 1 1 0 1 1 1 0 Lipid-binding putative hydrolase TRAM PF01938.15 KLO14867.1 - 0.11 12.3 0.0 0.16 11.7 0.0 1.4 1 0 0 1 1 1 0 TRAM domain COX16 PF14138.1 KLO14868.1 - 5.5e-29 100.1 0.2 6.5e-29 99.9 0.2 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein COX16 Tiny_TM_bacill PF09680.5 KLO14868.1 - 0.044 13.2 0.6 0.058 12.8 0.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (Tiny_TM_bacill) DUF3914 PF13053.1 KLO14868.1 - 0.054 13.6 0.3 0.084 13.0 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3914) ATP-synt_J PF04911.7 KLO14869.1 - 8.2e-16 57.2 0.0 9.8e-16 56.9 0.0 1.1 1 0 0 1 1 1 1 ATP synthase j chain DoxX_2 PF13564.1 KLO14869.1 - 0.057 13.3 0.0 0.057 13.3 0.0 1.2 1 0 0 1 1 1 0 DoxX-like family DUF4203 PF13886.1 KLO14870.1 - 1e-07 31.6 20.8 1.5e-07 31.0 14.4 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4203) MMR_HSR1 PF01926.18 KLO14871.1 - 5.9e-08 32.6 0.0 6.7e-07 29.2 0.0 2.3 2 0 0 2 2 2 1 50S ribosome-binding GTPase AIG1 PF04548.11 KLO14871.1 - 3.8e-07 29.4 0.0 1.4e-06 27.6 0.0 1.8 2 0 0 2 2 2 1 AIG1 family MACPF PF01823.14 KLO14871.1 - 1.1e-06 28.4 0.0 2.5e-06 27.3 0.0 1.5 1 0 0 1 1 1 1 MAC/Perforin domain DUF258 PF03193.11 KLO14871.1 - 3.1e-05 23.1 0.1 6.4e-05 22.1 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Septin PF00735.13 KLO14871.1 - 0.0074 15.3 0.0 0.012 14.6 0.0 1.3 1 0 0 1 1 1 1 Septin ABC_tran PF00005.22 KLO14871.1 - 0.011 16.0 0.0 0.028 14.6 0.0 1.7 1 0 0 1 1 1 0 ABC transporter ApoO PF09769.4 KLO14871.1 - 0.035 13.8 0.2 0.58 9.8 0.0 2.6 3 0 0 3 3 3 0 Apolipoprotein O FeoB_N PF02421.13 KLO14871.1 - 0.05 12.8 0.0 0.14 11.3 0.0 1.7 2 0 0 2 2 2 0 Ferrous iron transport protein B Peptidase_C10 PF01640.12 KLO14871.1 - 0.064 13.0 0.0 0.14 11.8 0.0 1.5 1 0 0 1 1 1 0 Peptidase C10 family Gtr1_RagA PF04670.7 KLO14871.1 - 0.14 11.2 0.0 0.24 10.5 0.0 1.3 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region FtsK_SpoIIIE PF01580.13 KLO14871.1 - 0.18 11.2 0.2 0.36 10.2 0.1 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family Het-C PF07217.6 KLO14872.1 - 1e-178 595.3 0.1 2.3e-106 356.3 0.1 3.0 3 0 0 3 3 3 3 Heterokaryon incompatibility protein Het-C Prenyltransf PF01255.14 KLO14873.1 - 1.7e-79 266.0 0.0 2e-79 265.8 0.0 1.0 1 0 0 1 1 1 1 Putative undecaprenyl diphosphate synthase HSF_DNA-bind PF00447.12 KLO14874.1 - 3.2e-36 123.6 4.8 1e-35 122.0 3.3 1.9 1 0 0 1 1 1 1 HSF-type DNA-binding Response_reg PF00072.19 KLO14874.1 - 1e-23 83.4 0.2 2.2e-23 82.3 0.2 1.6 1 0 0 1 1 1 1 Response regulator receiver domain Dyp_perox PF04261.7 KLO14875.1 - 2.5e-08 33.0 0.0 7.1e-08 31.5 0.0 1.8 1 1 0 1 1 1 1 Dyp-type peroxidase family RicinB_lectin_2 PF14200.1 KLO14875.1 - 0.005 17.1 1.0 0.098 13.0 0.6 2.5 1 1 1 2 2 2 1 Ricin-type beta-trefoil lectin domain-like GMC_oxred_C PF05199.8 KLO14876.1 - 1.4e-17 64.2 0.0 3.1e-17 63.2 0.0 1.6 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_N PF00732.14 KLO14876.1 - 1.8e-06 27.3 0.0 1e-05 24.8 0.0 1.9 2 0 0 2 2 2 1 GMC oxidoreductase RicinB_lectin_2 PF14200.1 KLO14876.1 - 0.0012 19.2 2.0 0.038 14.3 0.2 2.6 1 1 1 2 2 2 1 Ricin-type beta-trefoil lectin domain-like GerE PF00196.14 KLO14876.1 - 0.13 11.6 0.0 0.27 10.5 0.0 1.4 1 0 0 1 1 1 0 Bacterial regulatory proteins, luxR family VWA_2 PF13519.1 KLO14877.1 - 1.4e-16 61.0 0.0 2.5e-16 60.2 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.23 KLO14877.1 - 1.1e-07 31.7 0.0 2.1e-07 30.8 0.0 1.6 1 0 0 1 1 1 1 von Willebrand factor type A domain Med25_VWA PF11265.3 KLO14877.1 - 0.022 13.7 0.0 0.036 13.1 0.0 1.4 1 0 0 1 1 1 0 Mediator complex subunit 25 von Willebrand factor type A CNH PF00780.17 KLO14878.1 - 0.04 13.3 0.0 0.31 10.4 0.0 2.1 1 1 1 2 2 2 0 CNH domain HALZ PF02183.13 KLO14878.1 - 0.22 11.2 0.7 0.38 10.5 0.5 1.4 1 0 0 1 1 1 0 Homeobox associated leucine zipper NAD_binding_10 PF13460.1 KLO14879.1 - 5.5e-21 75.3 0.1 6.3e-21 75.2 0.0 1.0 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 KLO14879.1 - 4.8e-10 39.2 0.0 6.8e-10 38.7 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.8 KLO14879.1 - 2.5e-07 30.2 0.0 4.5e-07 29.3 0.0 1.4 1 0 0 1 1 1 1 NmrA-like family adh_short PF00106.20 KLO14879.1 - 4.7e-06 26.6 0.0 1e-05 25.5 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KLO14879.1 - 8.1e-05 22.3 0.0 0.00016 21.4 0.0 1.4 1 0 0 1 1 1 1 KR domain 3Beta_HSD PF01073.14 KLO14879.1 - 0.00031 19.5 0.0 0.00047 18.9 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family TrkA_N PF02254.13 KLO14879.1 - 0.0004 20.3 0.0 0.0007 19.5 0.0 1.6 1 1 0 1 1 1 1 TrkA-N domain F420_oxidored PF03807.12 KLO14879.1 - 0.044 14.2 0.0 0.091 13.2 0.0 1.6 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent 2-Hacid_dh_C PF02826.14 KLO14879.1 - 0.066 12.3 0.0 11 5.1 0.0 2.6 2 1 1 3 3 3 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain RmlD_sub_bind PF04321.12 KLO14879.1 - 0.12 11.2 0.0 0.19 10.6 0.0 1.3 1 0 0 1 1 1 0 RmlD substrate binding domain F-box-like PF12937.2 KLO14880.1 - 1.7e-07 30.8 1.2 7.8e-07 28.7 0.8 2.2 1 1 0 1 1 1 1 F-box-like PBP PF01161.15 KLO14881.1 - 4.7e-16 58.9 0.0 6.6e-16 58.4 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein F-box-like PF12937.2 KLO14882.1 - 1.9e-07 30.7 4.6 5.7e-07 29.1 3.2 1.9 1 1 0 1 1 1 1 F-box-like LRR_8 PF13855.1 KLO14882.1 - 0.00068 19.3 1.1 8.4 6.2 0.0 5.2 5 1 0 5 5 5 1 Leucine rich repeat LRR_4 PF12799.2 KLO14882.1 - 1.2 8.8 6.7 5.7 6.6 0.5 4.4 4 2 1 5 5 5 0 Leucine Rich repeats (2 copies) Pkinase_Tyr PF07714.12 KLO14883.1 - 3.1e-45 154.2 0.0 3.2e-44 150.9 0.0 2.5 3 1 0 3 3 3 1 Protein tyrosine kinase Pkinase PF00069.20 KLO14883.1 - 6.8e-40 136.8 0.0 2.1e-39 135.2 0.0 1.8 1 0 0 1 1 1 1 Protein kinase domain RasGEF PF00617.14 KLO14883.1 - 6.3e-28 97.7 0.0 1.5e-27 96.5 0.0 1.7 1 0 0 1 1 1 1 RasGEF domain Kinase-like PF14531.1 KLO14883.1 - 0.00049 19.1 0.0 0.0012 17.9 0.0 1.6 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 KLO14883.1 - 0.0078 15.3 0.0 0.048 12.7 0.0 2.3 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family RasGEF PF00617.14 KLO14885.1 - 2.3e-26 92.6 0.0 5e-26 91.5 0.0 1.5 1 0 0 1 1 1 1 RasGEF domain DRY_EERY PF09750.4 KLO14886.1 - 0.21 11.7 1.1 0.33 11.0 0.7 1.5 1 1 0 1 1 1 0 Alternative splicing regulator Per1 PF04080.8 KLO14887.1 - 4.3e-94 314.8 1.3 5.4e-94 314.5 0.9 1.1 1 0 0 1 1 1 1 Per1-like DUF3292 PF11696.3 KLO14888.1 - 0.13 10.1 1.2 0.2 9.4 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3292) Adenylsucc_synt PF00709.16 KLO14889.1 - 8.2e-158 525.4 0.0 9.4e-158 525.2 0.0 1.0 1 0 0 1 1 1 1 Adenylosuccinate synthetase Clathrin PF00637.15 KLO14890.1 - 5.8e-17 61.6 0.4 1.2e-12 47.6 0.1 3.4 3 0 0 3 3 3 2 Region in Clathrin and VPS VPS11_C PF12451.3 KLO14890.1 - 1.8e-08 34.1 0.1 3.4e-08 33.2 0.0 1.5 1 0 0 1 1 1 1 Vacuolar protein sorting protein 11 C terminal zf-C3HC4_2 PF13923.1 KLO14890.1 - 0.075 13.0 7.0 0.14 12.2 4.8 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KLO14890.1 - 0.097 12.4 7.5 0.16 11.6 5.2 1.4 1 0 0 1 1 1 0 zinc-RING finger domain zf-RING_2 PF13639.1 KLO14890.1 - 0.15 11.8 7.5 0.29 10.9 5.2 1.5 1 0 0 1 1 1 0 Ring finger domain zf-RING_6 PF14835.1 KLO14890.1 - 0.45 10.3 1.9 1 9.2 1.3 1.5 1 0 0 1 1 1 0 zf-RING of BARD1-type protein But2 PF09792.4 KLO14891.1 - 2.4e-06 27.3 0.0 3.6e-06 26.7 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin 3 binding protein But2 C-terminal domain zf-RING_2 PF13639.1 KLO14892.1 - 8.4e-05 22.3 10.3 8.4e-05 22.3 7.2 1.8 2 0 0 2 2 2 1 Ring finger domain SWIM PF04434.12 KLO14892.1 - 0.0026 17.2 0.2 0.0053 16.1 0.1 1.6 1 0 0 1 1 1 1 SWIM zinc finger zf-rbx1 PF12678.2 KLO14892.1 - 0.0069 16.4 4.8 0.016 15.3 3.3 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger C1_1 PF00130.17 KLO14892.1 - 0.01 15.5 8.3 0.01 15.5 5.7 2.7 2 1 1 3 3 3 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Baseplate_J PF04865.9 KLO14892.1 - 0.079 12.2 0.0 0.14 11.4 0.0 1.3 1 0 0 1 1 1 0 Baseplate J-like protein zf-C3HC4_2 PF13923.1 KLO14892.1 - 0.1 12.6 10.7 0.28 11.2 7.4 1.8 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) FANCL_C PF11793.3 KLO14892.1 - 0.22 11.5 9.9 0.34 10.9 5.9 2.0 2 0 0 2 2 2 0 FANCL C-terminal domain PHD PF00628.24 KLO14892.1 - 0.52 10.0 12.2 0.99 9.1 8.4 1.5 1 0 0 1 1 1 0 PHD-finger DUF4206 PF13901.1 KLO14892.1 - 0.91 9.0 8.1 1.8 8.0 5.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4206) zf-C3HC4_3 PF13920.1 KLO14892.1 - 2 8.1 13.3 0.075 12.7 5.1 1.7 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Prok-RING_1 PF14446.1 KLO14892.1 - 2.8 7.7 12.2 11 5.8 7.5 2.2 1 1 1 2 2 2 0 Prokaryotic RING finger family 1 Terpene_synth_C PF03936.11 KLO14895.1 - 2.2e-18 66.4 0.1 3e-18 65.9 0.1 1.2 1 0 0 1 1 1 1 Terpene synthase family, metal binding domain DUF3429 PF11911.3 KLO14896.1 - 3.5e-39 134.0 13.4 4.6e-39 133.6 9.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3429) Tetraspannin PF00335.15 KLO14897.1 - 1.1e-07 31.3 16.8 1.6e-07 30.8 11.6 1.3 1 0 0 1 1 1 1 Tetraspanin family DUF4191 PF13829.1 KLO14897.1 - 0.012 14.7 6.0 1.4 7.9 0.0 2.5 2 1 1 3 3 3 0 Domain of unknown function (DUF4191) ResB PF05140.9 KLO14897.1 - 0.11 10.9 1.3 0.45 9.0 0.1 2.0 2 0 0 2 2 2 0 ResB-like family DUF2207 PF09972.4 KLO14897.1 - 3.8 5.9 5.6 7.4 5.0 2.3 2.0 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) Baculo_11_kDa PF06143.6 KLO14897.1 - 6.6 6.1 7.4 15 5.0 0.0 3.0 3 1 0 3 3 3 0 Baculovirus 11 kDa family DUF3321 PF11968.3 KLO14898.1 - 4.3e-60 203.0 0.0 5.7e-60 202.6 0.0 1.2 1 0 0 1 1 1 1 Putative methyltransferase (DUF3321) DUF3459 PF11941.3 KLO14898.1 - 0.044 13.9 0.2 0.091 12.9 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3459) DUF1802 PF08819.6 KLO14898.1 - 0.056 13.0 0.0 0.11 12.0 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1802) FAD-oxidase_C PF02913.14 KLO14899.1 - 5.2e-58 196.2 0.1 1.2e-57 195.1 0.0 1.6 2 0 0 2 2 2 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.18 KLO14899.1 - 9.9e-34 115.7 0.1 2e-33 114.7 0.1 1.6 1 0 0 1 1 1 1 FAD binding domain 5_nucleotid_C PF02872.13 KLO14900.1 - 1.4e-26 93.3 0.0 3e-26 92.2 0.0 1.5 1 0 0 1 1 1 1 5'-nucleotidase, C-terminal domain Metallophos PF00149.23 KLO14900.1 - 3.7e-11 42.8 0.6 6.7e-11 41.9 0.4 1.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 KLO14900.1 - 0.00015 21.6 0.0 0.0003 20.6 0.0 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain PGA_cap PF09587.5 KLO14900.1 - 0.0087 15.4 0.0 0.022 14.1 0.0 1.6 1 0 0 1 1 1 1 Bacterial capsule synthesis protein PGA_cap HTH_3 PF01381.17 KLO14901.1 - 7e-08 32.2 0.1 1.2e-07 31.4 0.1 1.4 1 0 0 1 1 1 1 Helix-turn-helix MBF1 PF08523.5 KLO14901.1 - 1.6e-06 28.0 0.1 0.00054 19.9 0.1 2.2 2 0 0 2 2 2 2 Multiprotein bridging factor 1 HTH_31 PF13560.1 KLO14901.1 - 0.00014 21.9 0.0 0.00024 21.2 0.0 1.5 1 1 0 1 1 1 1 Helix-turn-helix domain HTH_19 PF12844.2 KLO14901.1 - 0.00025 21.0 0.0 0.00047 20.1 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain Sigma70_r4 PF04545.11 KLO14901.1 - 0.0011 18.2 0.0 0.0023 17.1 0.0 1.5 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_38 PF13936.1 KLO14901.1 - 0.0047 16.4 0.1 0.014 14.8 0.0 1.8 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_25 PF13413.1 KLO14901.1 - 0.0084 15.7 0.0 0.018 14.6 0.0 1.7 1 1 0 1 1 1 1 Helix-turn-helix domain Sigma70_r4_2 PF08281.7 KLO14901.1 - 0.0094 15.3 0.0 0.02 14.3 0.0 1.5 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_23 PF13384.1 KLO14901.1 - 0.054 13.1 0.1 0.11 12.2 0.1 1.5 1 0 0 1 1 1 0 Homeodomain-like domain CENP-B_N PF04218.8 KLO14901.1 - 0.06 12.7 0.0 0.13 11.6 0.0 1.6 1 0 0 1 1 1 0 CENP-B N-terminal DNA-binding domain MBF1 PF08523.5 KLO14902.1 - 5.7e-22 77.5 2.3 1.1e-21 76.5 1.6 1.5 1 0 0 1 1 1 1 Multiprotein bridging factor 1 HTH_3 PF01381.17 KLO14902.1 - 2.7e-13 49.5 0.3 4.5e-13 48.8 0.2 1.3 1 0 0 1 1 1 1 Helix-turn-helix HTH_31 PF13560.1 KLO14902.1 - 7.2e-08 32.5 0.0 1.6e-07 31.3 0.0 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_19 PF12844.2 KLO14902.1 - 2.5e-07 30.6 0.0 3.6e-07 30.1 0.0 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_25 PF13413.1 KLO14902.1 - 0.03 13.9 0.1 0.049 13.2 0.1 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain Tubulin PF00091.20 KLO14903.1 - 7.9e-75 251.3 0.0 1.2e-74 250.7 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 KLO14903.1 - 6.3e-46 155.5 0.1 1.5e-45 154.3 0.0 1.6 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.4 KLO14903.1 - 1.7e-05 24.8 0.0 5.1e-05 23.3 0.0 1.8 1 1 0 1 1 1 1 Misato Segment II tubulin-like domain DEAD PF00270.24 KLO14904.1 - 2.6e-48 163.7 0.0 3.8e-47 159.9 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KLO14904.1 - 7e-10 38.6 0.0 1.8e-09 37.3 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 KLO14904.1 - 2.2e-05 24.3 0.0 7.5e-05 22.6 0.0 2.0 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C_2 PF13307.1 KLO14904.1 - 0.028 14.3 0.0 0.06 13.2 0.0 1.5 1 0 0 1 1 1 0 Helicase C-terminal domain RGS-like PF09128.6 KLO14904.1 - 0.052 13.0 0.0 0.096 12.1 0.0 1.4 1 0 0 1 1 1 0 Regulator of G protein signalling-like domain Serglycin PF04360.7 KLO14904.1 - 1.8 8.3 4.5 3 7.5 3.1 1.3 1 0 0 1 1 1 0 Serglycin Helicase_C PF00271.26 KLO14905.1 - 7.5e-06 25.7 0.0 7.5e-06 25.7 0.0 1.7 2 0 0 2 2 2 1 Helicase conserved C-terminal domain FAD_binding_3 PF01494.14 KLO14906.1 - 1.4e-14 53.9 5.3 8.4e-11 41.5 0.0 3.0 2 1 0 2 2 2 2 FAD binding domain SE PF08491.5 KLO14906.1 - 0.0039 16.0 0.0 0.026 13.3 0.0 2.0 2 0 0 2 2 2 1 Squalene epoxidase NAD_binding_8 PF13450.1 KLO14906.1 - 0.016 15.1 0.1 0.054 13.5 0.1 2.0 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain DUF4112 PF13430.1 KLO14907.1 - 1.8e-22 79.2 0.0 2.4e-22 78.8 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4112) WD40 PF00400.27 KLO14909.1 - 2.6e-42 141.2 21.4 4.8e-08 32.5 0.7 7.4 7 0 0 7 7 7 7 WD domain, G-beta repeat F-box-like PF12937.2 KLO14909.1 - 1.8e-13 49.9 4.8 4.4e-13 48.7 3.3 1.7 1 0 0 1 1 1 1 F-box-like Nup160 PF11715.3 KLO14909.1 - 1.3e-06 26.8 0.1 0.031 12.4 0.0 3.3 3 1 0 3 3 3 2 Nucleoporin Nup120/160 F-box PF00646.28 KLO14909.1 - 1.5e-06 27.7 2.4 3.9e-06 26.3 1.7 1.8 1 0 0 1 1 1 1 F-box domain MgtE_N PF03448.12 KLO14909.1 - 0.024 14.9 0.2 0.044 14.1 0.1 1.3 1 0 0 1 1 1 0 MgtE intracellular N domain PQQ_3 PF13570.1 KLO14909.1 - 0.041 14.1 0.1 5.6 7.3 0.0 3.6 3 0 0 3 3 3 0 PQQ-like domain PQQ_2 PF13360.1 KLO14909.1 - 0.051 13.0 0.1 1.8 7.9 0.0 2.4 2 1 0 3 3 3 0 PQQ-like domain SH3_9 PF14604.1 KLO14910.1 - 1e-08 34.6 0.0 1.8e-08 33.8 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 KLO14910.1 - 1.9e-06 27.1 0.0 4.1e-06 26.0 0.0 1.5 1 0 0 1 1 1 1 SH3 domain FAM163 PF15069.1 KLO14910.1 - 2.4e-06 28.1 5.2 4.9e-05 23.9 0.0 2.7 1 1 1 2 2 1 1 FAM163 family SH3_2 PF07653.12 KLO14910.1 - 1.2e-05 24.7 0.0 2.5e-05 23.6 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain Rifin_STEVOR PF02009.11 KLO14910.1 - 0.0003 20.5 2.0 0.00054 19.7 1.4 1.3 1 0 0 1 1 1 1 Rifin/stevor family MtrF PF09472.5 KLO14910.1 - 0.041 13.1 2.4 0.077 12.2 1.6 1.4 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, F subunit (MtrF) Adeno_E3_CR2 PF02439.10 KLO14910.1 - 0.049 13.1 0.6 0.097 12.2 0.4 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 vMSA PF00695.14 KLO14910.1 - 0.052 12.7 9.4 0.033 13.3 3.8 2.0 2 0 0 2 2 2 0 Major surface antigen from hepadnavirus EphA2_TM PF14575.1 KLO14910.1 - 0.083 13.2 0.0 0.21 11.9 0.0 1.7 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain hSH3 PF14603.1 KLO14910.1 - 0.51 10.3 0.0 0.51 10.3 0.0 1.9 2 0 0 2 2 2 0 Helically-extended SH3 domain Herpes_UL32 PF06070.6 KLO14910.1 - 2.8 6.3 17.0 3.8 5.8 11.8 1.2 1 0 0 1 1 1 0 Herpesvirus large structural phosphoprotein UL32 Peptidase_S64 PF08192.6 KLO14910.1 - 5.4 5.2 11.5 6.9 4.8 8.0 1.1 1 0 0 1 1 1 0 Peptidase family S64 Macoilin PF09726.4 KLO14910.1 - 9.5 4.3 14.6 13 3.9 10.1 1.1 1 0 0 1 1 1 0 Transmembrane protein SNF2_N PF00176.18 KLO14911.1 - 3.6e-31 108.0 0.0 5.5e-25 87.7 0.0 2.9 3 0 0 3 3 3 2 SNF2 family N-terminal domain Helicase_C PF00271.26 KLO14911.1 - 0.005 16.6 0.0 0.011 15.5 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Pam17 PF08566.5 KLO14912.1 - 5.3e-63 211.8 0.0 6.9e-63 211.4 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial import protein Pam17 DUF2833 PF11090.3 KLO14912.1 - 0.12 12.5 0.0 0.29 11.3 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2833) SH3_9 PF14604.1 KLO14913.1 - 6.4e-06 25.6 0.1 1.6e-05 24.3 0.0 1.7 2 0 0 2 2 2 1 Variant SH3 domain SH3_1 PF00018.23 KLO14913.1 - 8.8e-05 21.8 0.0 0.00019 20.7 0.0 1.6 1 0 0 1 1 1 1 SH3 domain Ebola_NP PF05505.7 KLO14913.1 - 4.7 5.1 5.8 6.5 4.6 4.1 1.1 1 0 0 1 1 1 0 Ebola nucleoprotein zf-CCCH PF00642.19 KLO14914.1 - 1.6e-06 27.6 1.1 2.3e-06 27.1 0.8 1.3 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) AAA_16 PF13191.1 KLO14915.1 - 6.9e-07 29.4 0.0 3.7e-05 23.7 0.0 2.7 1 1 0 2 2 2 1 AAA ATPase domain AAA_2 PF07724.9 KLO14915.1 - 1.8e-05 24.7 0.0 4.8e-05 23.3 0.0 1.7 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.9 KLO14915.1 - 2.1e-05 24.2 0.0 3.8e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA PF00004.24 KLO14915.1 - 2.5e-05 24.5 0.0 5.6e-05 23.3 0.0 1.7 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 KLO14915.1 - 4e-05 23.7 0.0 0.00017 21.7 0.0 2.0 1 1 0 1 1 1 1 AAA domain Ank_2 PF12796.2 KLO14915.1 - 0.00078 19.7 0.0 0.0015 18.8 0.0 1.3 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) AAA_33 PF13671.1 KLO14915.1 - 0.019 14.8 0.1 0.091 12.6 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.1 KLO14915.1 - 0.036 13.9 0.0 0.074 12.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain RuvB_N PF05496.7 KLO14915.1 - 0.052 12.5 0.0 0.085 11.8 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus Mg_chelatase PF01078.16 KLO14915.1 - 0.073 12.2 0.0 0.18 10.9 0.0 1.6 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.12 KLO14915.1 - 0.13 11.6 0.0 0.23 10.8 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein RNA_helicase PF00910.17 KLO14915.1 - 0.15 12.2 0.0 0.44 10.7 0.0 1.9 1 1 0 1 1 1 0 RNA helicase Kelch_6 PF13964.1 KLO14916.1 - 0.0032 17.5 0.9 2.5 8.4 0.0 3.2 3 0 0 3 3 3 2 Kelch motif Kelch_5 PF13854.1 KLO14916.1 - 0.14 12.1 5.1 7.4 6.6 0.0 3.7 5 0 0 5 5 5 0 Kelch motif Kelch_1 PF01344.20 KLO14916.1 - 0.15 11.6 3.9 7.5 6.1 0.0 3.0 3 0 0 3 3 3 0 Kelch motif Acetyltransf_1 PF00583.19 KLO14917.1 - 3.1e-10 39.9 0.2 4.6e-10 39.3 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 KLO14917.1 - 3.5e-05 23.8 0.0 6e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 KLO14917.1 - 0.00039 20.1 0.0 0.00065 19.4 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_4 PF13420.1 KLO14917.1 - 0.0011 18.9 0.0 0.0014 18.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 KLO14917.1 - 0.0059 16.4 0.0 0.0096 15.8 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 KLO14917.1 - 0.013 15.6 0.0 0.02 15.0 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 KLO14917.1 - 0.035 13.9 0.2 0.064 13.1 0.1 1.5 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain DUF1788 PF08747.6 KLO14918.1 - 0.097 12.5 0.1 0.22 11.3 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1788) DUF3608 PF12257.3 KLO14919.1 - 7.6e-59 198.9 0.0 4.4e-58 196.4 0.0 2.1 1 1 0 1 1 1 1 Protein of unknown function (DUF3608) DEP PF00610.16 KLO14919.1 - 8.4e-19 67.1 0.1 1.7e-18 66.1 0.1 1.5 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) DisA_N PF02457.11 KLO14919.1 - 0.23 10.5 0.0 0.55 9.3 0.0 1.6 1 0 0 1 1 1 0 DisA bacterial checkpoint controller nucleotide-binding DUF4551 PF15087.1 KLO14920.1 - 0.63 8.3 3.8 0.82 7.9 2.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) F-box-like PF12937.2 KLO14921.1 - 0.027 14.2 0.7 0.52 10.0 0.5 2.6 1 1 0 1 1 1 0 F-box-like Yip1 PF04893.12 KLO14922.1 - 0.04 13.4 0.0 0.04 13.4 0.0 2.0 2 1 0 2 2 2 0 Yip1 domain FixQ PF05545.6 KLO14922.1 - 0.19 11.4 0.3 0.37 10.4 0.2 1.4 1 0 0 1 1 1 0 Cbb3-type cytochrome oxidase component FixQ PSP PF04046.11 KLO14923.1 - 5.6e-05 22.4 0.4 0.0002 20.6 0.3 2.0 1 0 0 1 1 1 1 PSP zf-CCHC PF00098.18 KLO14923.1 - 0.00025 20.8 1.2 0.00041 20.1 0.8 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_4 PF14392.1 KLO14923.1 - 0.0038 16.8 0.5 0.0092 15.6 0.4 1.6 1 0 0 1 1 1 1 Zinc knuckle 4HBT_3 PF13622.1 KLO14923.1 - 0.28 10.8 4.3 0.52 10.0 3.0 1.4 1 0 0 1 1 1 0 Thioesterase-like superfamily CAP_N PF01213.14 KLO14923.1 - 0.65 9.2 4.3 1 8.6 3.0 1.3 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Mito_fiss_reg PF05308.6 KLO14923.1 - 2.4 7.4 6.5 4.2 6.6 4.5 1.3 1 0 0 1 1 1 0 Mitochondrial fission regulator Phage_lambda_P PF06992.6 KLO14924.1 - 0.089 12.0 0.1 0.15 11.3 0.1 1.4 1 1 0 1 1 1 0 Replication protein P DUF1054 PF06335.7 KLO14924.1 - 0.092 12.4 0.0 0.18 11.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1054) WD40 PF00400.27 KLO14925.1 - 2.3e-111 360.1 29.9 8.1e-11 41.3 0.1 13.7 13 0 0 13 13 13 13 WD domain, G-beta repeat NACHT PF05729.7 KLO14925.1 - 1.4e-07 31.3 0.0 4.2e-07 29.7 0.0 1.8 1 1 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 KLO14925.1 - 9e-06 25.7 0.0 2.3e-05 24.4 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain PQQ_2 PF13360.1 KLO14925.1 - 3.2e-05 23.5 3.9 0.00056 19.4 0.5 3.6 2 2 1 3 3 3 1 PQQ-like domain Nucleoporin_N PF08801.6 KLO14925.1 - 0.00011 21.1 5.0 0.032 12.9 0.4 4.3 2 1 2 4 4 4 2 Nup133 N terminal like PD40 PF07676.7 KLO14925.1 - 0.0019 17.8 0.2 12 5.7 0.0 4.6 4 0 0 4 4 4 1 WD40-like Beta Propeller Repeat AAA_22 PF13401.1 KLO14925.1 - 0.039 14.0 0.0 0.098 12.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.1 KLO14925.1 - 0.075 12.7 0.0 0.19 11.5 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain DUF3312 PF11768.3 KLO14925.1 - 0.11 10.7 0.0 41 2.2 0.0 3.7 3 1 1 4 4 4 0 Protein of unknown function (DUF3312) NB-ARC PF00931.17 KLO14925.1 - 0.13 11.0 0.0 0.27 10.0 0.0 1.5 1 0 0 1 1 1 0 NB-ARC domain Peptidase_M29 PF02073.10 KLO14925.1 - 0.18 10.5 0.0 0.35 9.6 0.0 1.4 1 0 0 1 1 1 0 Thermophilic metalloprotease (M29) Cyclin_N PF00134.18 KLO14928.1 - 5.1e-14 51.9 0.0 8.5e-14 51.2 0.0 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.6 KLO14928.1 - 9.8e-10 39.0 0.1 9.8e-10 39.0 0.0 1.6 2 0 0 2 2 2 1 Cyclin DJ-1_PfpI PF01965.19 KLO14931.1 - 1.9e-19 69.5 0.2 2.4e-19 69.2 0.1 1.2 1 0 0 1 1 1 1 DJ-1/PfpI family DJ-1_PfpI_N PF13587.1 KLO14931.1 - 4.8e-13 48.3 0.2 7.6e-13 47.7 0.2 1.3 1 0 0 1 1 1 1 N-terminal domain of DJ-1_PfpI family LcrG PF07216.7 KLO14931.1 - 0.091 12.7 0.0 0.18 11.8 0.0 1.5 2 0 0 2 2 2 0 LcrG protein DJ-1_PfpI PF01965.19 KLO14932.1 - 2.2e-22 79.0 0.1 3.5e-22 78.4 0.1 1.3 1 0 0 1 1 1 1 DJ-1/PfpI family DJ-1_PfpI_N PF13587.1 KLO14932.1 - 1.5e-07 30.8 0.2 3.3e-07 29.6 0.1 1.5 1 0 0 1 1 1 1 N-terminal domain of DJ-1_PfpI family tRNA-synt_2c PF01411.14 KLO14933.1 - 2.3e-10 39.3 0.0 3e-10 39.0 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (A) tRNA_SAD PF07973.9 KLO14933.1 - 0.00092 19.0 0.0 0.002 17.9 0.0 1.5 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain zf-RING_2 PF13639.1 KLO14934.1 - 4.8e-09 35.9 2.6 3.7e-08 33.0 0.4 2.2 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.1 KLO14934.1 - 2.6e-07 30.5 2.7 1.2e-06 28.4 0.2 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KLO14934.1 - 9.3e-06 25.2 3.2 7.4e-05 22.3 2.3 2.1 1 1 1 2 2 2 1 zinc-RING finger domain zf-C3HC4 PF00097.20 KLO14934.1 - 2.5e-05 23.8 0.9 9.7e-05 21.9 0.7 1.9 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 KLO14934.1 - 0.00052 19.8 0.1 0.025 14.3 0.1 2.2 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.2 KLO14934.1 - 0.0006 19.8 1.1 0.0015 18.6 0.8 1.6 1 1 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_3 PF13920.1 KLO14934.1 - 0.0011 18.6 0.6 0.032 13.9 0.1 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 KLO14934.1 - 0.0027 17.5 1.2 0.0027 17.5 0.9 2.2 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 KLO14934.1 - 0.0036 16.9 0.6 0.0036 16.9 0.4 2.1 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_6 PF14835.1 KLO14934.1 - 0.0048 16.6 2.3 0.008 15.9 0.4 1.9 2 0 0 2 2 2 1 zf-RING of BARD1-type protein zf-RING_4 PF14570.1 KLO14934.1 - 0.017 14.6 2.1 0.027 14.0 0.2 2.2 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-MYND PF01753.13 KLO14935.1 - 1.5e-10 40.7 15.3 3.4e-10 39.6 10.6 1.6 1 0 0 1 1 1 1 MYND finger zf-Mss51 PF13824.1 KLO14935.1 - 0.045 13.6 4.8 0.11 12.3 3.3 1.7 1 0 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 PolC_DP2 PF03833.8 KLO14935.1 - 1.8 6.1 4.9 2.6 5.5 3.4 1.1 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 Ecl1 PF12855.2 KLO14935.1 - 8.8 5.7 10.6 20 4.5 7.3 1.6 1 0 0 1 1 1 0 Life-span regulatory factor CTD_bind PF04818.8 KLO14940.1 - 0.00015 21.9 0.0 0.00045 20.4 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase II-binding domain. MOZART1 PF12554.3 KLO14940.1 - 0.011 15.2 0.1 0.021 14.2 0.1 1.4 1 0 0 1 1 1 0 Mitotic-spindle organizing gamma-tubulin ring associated zf-C2H2_4 PF13894.1 KLO14940.1 - 0.067 13.5 0.8 0.46 10.9 0.0 2.6 3 0 0 3 3 3 0 C2H2-type zinc finger zf-RVT PF13966.1 KLO14941.1 - 0.00024 21.3 0.1 0.00038 20.7 0.1 1.4 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase NEMO PF11577.3 KLO14944.1 - 0.16 11.7 4.0 2.8 7.7 0.2 2.5 2 0 0 2 2 2 0 NF-kappa-B essential modulator NEMO bZIP_1 PF00170.16 KLO14944.1 - 0.82 9.6 6.3 1.2 9.1 0.8 2.4 2 0 0 2 2 2 0 bZIP transcription factor Ribosomal_L6 PF00347.18 KLO14945.1 - 3.8e-27 94.5 5.1 8.9e-15 54.9 1.0 2.1 2 0 0 2 2 2 2 Ribosomal protein L6 FAD_binding_7 PF03441.9 KLO14947.1 - 3e-93 312.0 1.8 6.6e-93 310.9 1.2 1.5 1 1 0 1 1 1 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.13 KLO14947.1 - 2.3e-36 125.0 0.0 4.9e-36 123.9 0.0 1.5 1 0 0 1 1 1 1 DNA photolyase Phosducin PF02114.11 KLO14948.1 - 1e-06 27.7 0.3 1.3e-06 27.3 0.2 1.1 1 0 0 1 1 1 1 Phosducin Thioredoxin PF00085.15 KLO14948.1 - 0.0012 18.5 0.4 0.0022 17.6 0.1 1.6 2 0 0 2 2 2 1 Thioredoxin DUF2968 PF11180.3 KLO14948.1 - 0.093 12.1 0.4 0.13 11.6 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) eRF1_1 PF03463.10 KLO14949.1 - 2.7e-42 143.4 0.0 4.1e-42 142.8 0.0 1.3 1 0 0 1 1 1 1 eRF1 domain 1 eRF1_3 PF03465.10 KLO14949.1 - 6e-22 78.0 0.0 1.2e-21 77.0 0.0 1.5 1 0 0 1 1 1 1 eRF1 domain 3 eRF1_2 PF03464.10 KLO14949.1 - 6.7e-22 78.2 0.0 1e-21 77.6 0.0 1.3 1 0 0 1 1 1 1 eRF1 domain 2 DUF680 PF05079.7 KLO14949.1 - 0.1 13.1 1.5 0.46 11.0 1.0 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF680) HLH PF00010.21 KLO14950.1 - 5.6e-15 54.7 0.3 1.4e-14 53.4 0.2 1.8 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain DDE_Tnp_1_3 PF13612.1 KLO14950.1 - 0.12 12.1 0.2 0.18 11.5 0.1 1.2 1 0 0 1 1 1 0 Transposase DDE domain AAA PF00004.24 KLO14951.1 - 8.6e-08 32.4 0.0 5.6e-05 23.3 0.0 2.3 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.1 KLO14951.1 - 0.00058 19.5 0.0 0.0011 18.7 0.0 1.4 1 0 0 1 1 1 1 Part of AAA domain AAA_16 PF13191.1 KLO14951.1 - 0.0015 18.5 0.1 0.002 18.1 0.0 1.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_17 PF13207.1 KLO14951.1 - 0.004 17.9 0.0 0.0068 17.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain TIP49 PF06068.8 KLO14951.1 - 0.0041 15.8 0.0 0.0056 15.4 0.0 1.1 1 0 0 1 1 1 1 TIP49 C-terminus AAA_5 PF07728.9 KLO14951.1 - 0.0059 16.3 0.0 0.025 14.3 0.0 2.0 2 1 1 3 3 3 1 AAA domain (dynein-related subfamily) Zeta_toxin PF06414.7 KLO14951.1 - 0.0081 15.2 0.0 0.012 14.6 0.0 1.2 1 0 0 1 1 1 1 Zeta toxin Rad17 PF03215.10 KLO14951.1 - 0.011 14.4 0.0 0.23 10.1 0.0 2.0 2 0 0 2 2 2 0 Rad17 cell cycle checkpoint protein AAA_33 PF13671.1 KLO14951.1 - 0.016 15.0 0.0 0.028 14.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain RuvB_N PF05496.7 KLO14951.1 - 0.018 14.1 0.0 0.027 13.5 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus T2SE PF00437.15 KLO14951.1 - 0.036 12.9 0.0 0.05 12.4 0.0 1.1 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_22 PF13401.1 KLO14951.1 - 0.074 13.1 0.1 0.15 12.1 0.0 1.5 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.1 KLO14951.1 - 0.12 12.6 0.0 0.21 11.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain Cupin_8 PF13621.1 KLO14953.1 - 1.1e-58 198.7 0.0 1.3e-58 198.5 0.0 1.0 1 0 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.7 KLO14953.1 - 0.00023 20.5 0.0 0.00041 19.6 0.0 1.4 1 0 0 1 1 1 1 Cupin superfamily protein JmjC PF02373.17 KLO14953.1 - 0.00042 20.5 0.0 0.0012 19.0 0.0 1.8 1 1 0 1 1 1 1 JmjC domain, hydroxylase Cupin_2 PF07883.6 KLO14953.1 - 0.0013 18.1 0.2 0.012 15.1 0.0 2.3 2 0 0 2 2 2 1 Cupin domain Med20 PF08612.6 KLO14954.1 - 3.1e-10 39.5 0.1 2.5e-09 36.6 0.1 2.0 1 1 0 1 1 1 1 TATA-binding related factor (TRF) of subunit 20 of Mediator complex ORC4_C PF14629.1 KLO14955.1 - 1.4e-24 86.6 0.0 3.1e-24 85.5 0.0 1.6 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 4 C-terminus AAA_16 PF13191.1 KLO14955.1 - 2.2e-18 66.9 0.2 5.5e-18 65.6 0.1 1.7 1 0 0 1 1 1 1 AAA ATPase domain Arch_ATPase PF01637.13 KLO14955.1 - 0.0013 18.4 0.0 0.0025 17.5 0.0 1.4 1 0 0 1 1 1 1 Archaeal ATPase AAA_22 PF13401.1 KLO14955.1 - 0.0068 16.5 0.0 0.015 15.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA PF00004.24 KLO14955.1 - 0.026 14.7 0.0 0.14 12.3 0.0 2.1 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.1 KLO14955.1 - 0.074 12.8 0.1 0.24 11.1 0.0 1.9 2 0 0 2 2 2 0 Part of AAA domain BCDHK_Adom3 PF10436.4 KLO14956.1 - 1.4e-40 138.5 0.0 2e-40 137.9 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.21 KLO14956.1 - 1.4e-12 47.3 0.0 3e-12 46.2 0.0 1.6 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.1 KLO14956.1 - 0.083 12.5 0.0 0.13 11.8 0.0 1.4 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase IcmL PF11393.3 KLO14957.1 - 0.18 11.7 3.1 0.63 9.9 0.3 2.3 2 0 0 2 2 2 0 Macrophage killing protein with similarity to conjugation protein zf-RING_2 PF13639.1 KLO14959.1 - 2.1e-08 33.8 5.2 2.2e-07 30.6 3.6 2.1 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 KLO14959.1 - 1e-06 28.2 0.3 2.5e-06 27.0 0.2 1.7 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KLO14959.1 - 1.1e-06 28.5 3.8 1.5e-05 24.8 0.6 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 KLO14959.1 - 2e-06 27.7 0.2 3.5e-06 27.0 0.2 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_5 PF14634.1 KLO14959.1 - 2.8e-06 26.9 0.9 3.8e-05 23.3 0.4 2.1 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 KLO14959.1 - 2.6e-05 23.7 1.1 0.00038 20.0 0.3 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 KLO14959.1 - 0.0011 18.6 1.5 0.0035 17.0 0.1 2.3 2 0 0 2 2 2 1 RING-type zinc-finger Prok-RING_4 PF14447.1 KLO14959.1 - 0.0052 16.2 0.6 0.0052 16.2 0.4 2.3 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 FNIP_N PF14636.1 KLO14959.1 - 0.008 16.6 2.8 0.013 16.0 1.9 1.3 1 0 0 1 1 1 1 Folliculin-interacting protein N-terminus zf-RING_4 PF14570.1 KLO14959.1 - 0.028 13.9 5.0 0.033 13.7 1.4 2.1 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-C3HC4_4 PF15227.1 KLO14959.1 - 0.035 13.9 4.9 0.07 13.0 0.7 2.5 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-RING_6 PF14835.1 KLO14959.1 - 0.036 13.8 0.6 0.42 10.4 0.2 2.2 2 0 0 2 2 2 0 zf-RING of BARD1-type protein zf-C2HC5 PF06221.8 KLO14959.1 - 0.053 13.2 0.1 0.12 12.1 0.1 1.5 1 0 0 1 1 1 0 Putative zinc finger motif, C2HC5-type zf-RING_3 PF14369.1 KLO14959.1 - 0.074 13.0 4.0 2.2 8.3 0.5 2.5 2 0 0 2 2 2 0 zinc-finger zf-Nse PF11789.3 KLO14959.1 - 0.084 12.4 1.9 0.21 11.1 1.3 1.7 1 1 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-P11 PF03854.9 KLO14959.1 - 0.12 11.9 0.4 0.56 9.7 0.0 1.9 2 0 0 2 2 2 0 P-11 zinc finger zf-Apc11 PF12861.2 KLO14959.1 - 0.12 12.2 0.2 0.66 9.8 0.1 1.9 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger Spo12 PF05032.7 KLO14960.1 - 2e-10 40.1 3.0 4.3e-10 39.0 2.0 1.6 1 0 0 1 1 1 1 Spo12 family Pheromone PF08015.6 KLO14960.1 - 7.9 7.3 10.3 1.3 9.8 4.3 1.8 2 1 0 2 2 2 0 Fungal mating-type pheromone Ras PF00071.17 KLO14961.1 - 3e-44 150.2 0.1 3.4e-44 150.0 0.1 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KLO14961.1 - 1.6e-17 64.0 0.1 2.4e-17 63.5 0.1 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KLO14961.1 - 3.4e-08 32.9 0.0 4.6e-08 32.5 0.0 1.2 1 1 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 KLO14961.1 - 0.0003 20.7 0.0 0.00052 19.9 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.5 KLO14961.1 - 0.00077 18.7 0.1 0.0012 18.0 0.0 1.4 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit FeoB_N PF02421.13 KLO14961.1 - 0.0044 16.3 0.0 0.37 10.0 0.0 2.1 2 0 0 2 2 2 1 Ferrous iron transport protein B AAA_14 PF13173.1 KLO14961.1 - 0.005 16.7 0.0 0.0079 16.1 0.0 1.5 1 1 0 1 1 1 1 AAA domain Arch_ATPase PF01637.13 KLO14961.1 - 0.0075 15.9 0.1 0.01 15.5 0.1 1.5 1 1 0 1 1 1 1 Archaeal ATPase AAA_16 PF13191.1 KLO14961.1 - 0.042 13.8 0.0 0.074 13.0 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain AAA_28 PF13521.1 KLO14961.1 - 0.076 12.9 0.0 3.4 7.5 0.0 2.5 3 0 0 3 3 3 0 AAA domain PduV-EutP PF10662.4 KLO14961.1 - 0.08 12.4 0.2 0.21 11.0 0.2 2.1 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation MobB PF03205.9 KLO14961.1 - 0.089 12.4 0.2 0.16 11.6 0.0 1.5 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B Glyco_hydro_2_C PF02836.12 KLO14962.1 - 0.0016 17.4 0.0 0.0026 16.6 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Glyco_hydro_2_N PF02837.13 KLO14962.1 - 0.0021 17.6 0.0 0.0041 16.6 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain Sugar_tr PF00083.19 KLO14963.1 - 1.5e-87 294.1 15.9 1.7e-87 293.8 11.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KLO14963.1 - 1.2e-37 129.4 34.1 1.1e-34 119.6 11.7 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 KLO14963.1 - 7.8e-08 31.1 20.9 1.4e-06 26.9 3.7 2.6 3 0 0 3 3 3 2 MFS/sugar transport protein TRI12 PF06609.8 KLO14963.1 - 0.00083 17.6 1.7 0.0014 16.9 1.2 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) BT1 PF03092.11 KLO14963.1 - 0.0071 15.0 0.3 0.012 14.3 0.2 1.6 1 1 0 1 1 1 1 BT1 family MFS_1_like PF12832.2 KLO14963.1 - 0.013 15.3 7.5 0.32 10.8 0.0 3.6 3 0 0 3 3 3 0 MFS_1 like family MFS_3 PF05977.8 KLO14963.1 - 0.33 9.0 9.4 0.72 7.8 0.1 3.3 2 2 0 2 2 2 0 Transmembrane secretion effector FimP PF09766.4 KLO14964.1 - 1.1e-27 97.0 6.6 1.5e-27 96.5 4.6 1.2 1 0 0 1 1 1 1 Fms-interacting protein TMF_DNA_bd PF12329.3 KLO14964.1 - 7.4e-05 22.4 3.2 7.4e-05 22.4 2.2 2.3 2 1 0 2 2 2 1 TATA element modulatory factor 1 DNA binding Seryl_tRNA_N PF02403.17 KLO14964.1 - 0.049 13.6 7.3 2.2 8.3 2.1 2.7 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain CDC37_N PF03234.9 KLO14964.1 - 0.28 11.5 6.4 0.39 11.0 4.4 1.2 1 0 0 1 1 1 0 Cdc37 N terminal kinase binding DUF4200 PF13863.1 KLO14964.1 - 0.33 10.9 8.8 0.19 11.7 1.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) Filament PF00038.16 KLO14964.1 - 0.57 9.5 12.7 1.8 7.9 3.1 2.1 1 1 1 2 2 2 0 Intermediate filament protein DUF948 PF06103.6 KLO14964.1 - 1.4 8.8 6.3 4 7.3 4.3 1.8 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF948) UQ_con PF00179.21 KLO14965.1 - 2.1e-37 127.6 0.1 2.7e-37 127.3 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_E PF14462.1 KLO14965.1 - 0.027 14.0 0.1 0.78 9.3 0.0 2.2 2 0 0 2 2 2 0 Prokaryotic E2 family E Integrase_AP2 PF14657.1 KLO14965.1 - 0.072 12.8 0.1 0.13 12.0 0.0 1.4 1 0 0 1 1 1 0 AP2-like DNA-binding integrase domain GST_N_3 PF13417.1 KLO14966.1 - 3.2e-13 49.7 0.0 7.8e-13 48.4 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 KLO14966.1 - 5.6e-11 42.2 0.0 9.4e-11 41.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 KLO14966.1 - 0.0002 21.1 0.0 0.00055 19.7 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 KLO14966.1 - 0.00037 20.4 0.0 0.00079 19.3 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 KLO14966.1 - 0.0011 19.1 0.0 0.0029 17.7 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 KLO14966.1 - 0.018 15.5 0.0 0.026 14.9 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain AHS1 PF02682.11 KLO14966.1 - 0.12 11.8 0.0 0.19 11.1 0.0 1.2 1 0 0 1 1 1 0 Allophanate hydrolase subunit 1 Ecm33 PF12454.3 KLO14968.1 - 4.2 7.3 9.3 0.24 11.2 0.5 2.8 4 0 0 4 4 4 0 GPI-anchored cell wall organization protein DUF2298 PF10060.4 KLO14970.1 - 0.073 11.9 1.1 0.087 11.6 0.8 1.0 1 0 0 1 1 1 0 Uncharacterized membrane protein (DUF2298) MARVEL PF01284.18 KLO14971.1 - 0.0054 16.5 11.6 0.0082 15.9 8.0 1.3 1 0 0 1 1 1 1 Membrane-associating domain DUF751 PF05421.6 KLO14971.1 - 1.4 9.2 7.6 0.19 12.0 1.5 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF751) PhaG_MnhG_YufB PF03334.9 KLO14971.1 - 9.7 6.3 11.4 1.9 8.5 4.3 2.2 2 0 0 2 2 2 0 Na+/H+ antiporter subunit DUF4131 PF13567.1 KLO14972.1 - 0.024 14.0 0.9 0.024 14.0 0.6 3.0 4 0 0 4 4 4 0 Domain of unknown function (DUF4131) MARVEL PF01284.18 KLO14972.1 - 0.083 12.7 16.2 0.23 11.2 10.5 2.1 1 1 1 2 2 2 0 Membrane-associating domain AMP-binding PF00501.23 KLO14973.1 - 1.3e-42 145.6 0.0 1.9e-42 145.1 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme DUF4260 PF14079.1 KLO14973.1 - 0.1 12.4 0.1 0.24 11.2 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4260) DUF1754 PF08555.5 KLO14974.1 - 0.055 14.0 0.2 0.085 13.4 0.1 1.3 1 0 0 1 1 1 0 Eukaryotic family of unknown function (DUF1754) Ecm33 PF12454.3 KLO14975.1 - 0.59 10.0 6.2 0.24 11.2 0.5 2.6 3 0 0 3 3 3 0 GPI-anchored cell wall organization protein F-box-like PF12937.2 KLO14976.1 - 0.014 15.1 0.2 0.03 14.0 0.1 1.6 1 0 0 1 1 1 0 F-box-like F-box-like PF12937.2 KLO14977.1 - 0.041 13.6 0.1 0.11 12.2 0.0 1.8 1 0 0 1 1 1 0 F-box-like Chitin_synth_1 PF01644.12 KLO14978.1 - 9.5e-61 204.3 0.0 1.5e-60 203.6 0.0 1.3 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.6 KLO14978.1 - 2.7e-27 94.2 0.0 5.7e-27 93.2 0.0 1.5 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.10 KLO14978.1 - 1.6e-24 86.1 0.0 1.1e-20 73.5 0.0 2.4 2 0 0 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.1 KLO14978.1 - 1.5e-11 44.3 0.0 1.5e-11 44.3 0.0 2.4 1 1 1 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 KLO14978.1 - 1.7e-08 34.5 0.0 5.2e-08 32.9 0.0 1.7 2 0 0 2 2 2 1 Glycosyltransferase like family 2 F-box-like PF12937.2 KLO14979.1 - 3.3e-05 23.5 1.2 0.0002 20.9 0.0 3.0 3 0 0 3 3 3 1 F-box-like Ribosomal_L7Ae PF01248.21 KLO14980.1 - 1.5e-24 85.2 0.4 2.5e-24 84.6 0.3 1.4 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family DUF3759 PF12585.3 KLO14981.1 - 3.2e-38 129.5 5.1 3.8e-38 129.2 3.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3759) DUF3759 PF12585.3 KLO14982.1 - 1.3e-38 130.7 4.8 1.5e-38 130.5 3.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3759) Spo12 PF05032.7 KLO14985.1 - 0.14 11.7 0.2 0.26 10.9 0.1 1.4 1 0 0 1 1 1 0 Spo12 family Snf7 PF03357.16 KLO14988.1 - 5e-34 117.1 17.0 5e-34 117.1 11.8 2.0 1 1 1 2 2 2 1 Snf7 DUF3636 PF12331.3 KLO14988.1 - 0.084 12.4 0.6 0.18 11.3 0.1 1.7 2 1 0 2 2 2 0 Protein of unknown function (DUF3636) Avirulence PF03377.8 KLO14988.1 - 0.11 11.1 0.0 0.14 10.8 0.0 1.1 1 0 0 1 1 1 0 Xanthomonas avirulence protein, Avr/PthA NIF PF03031.13 KLO14989.1 - 5.2e-50 169.2 0.0 8.5e-50 168.5 0.0 1.3 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase CLPTM1 PF05602.7 KLO14990.1 - 4.3e-140 467.2 0.0 5.4e-140 466.9 0.0 1.1 1 0 0 1 1 1 1 Cleft lip and palate transmembrane protein 1 (CLPTM1) PQ-loop PF04193.9 KLO14990.1 - 0.00068 19.1 0.5 0.00068 19.1 0.3 2.6 3 0 0 3 3 3 1 PQ loop repeat 2TM PF13239.1 KLO14990.1 - 0.5 10.4 5.7 0.26 11.3 1.0 2.6 2 0 0 2 2 2 0 2TM domain zf-MYND PF01753.13 KLO14993.1 - 6.6e-10 38.7 14.0 6.6e-10 38.7 9.7 1.7 2 0 0 2 2 2 1 MYND finger ASCH PF04266.9 KLO14993.1 - 0.11 12.8 0.0 5.1 7.5 0.0 2.9 3 0 0 3 3 3 0 ASCH domain zf-C3HC4_2 PF13923.1 KLO14994.1 - 1.4e-08 34.6 16.4 1.4e-08 34.6 11.4 3.3 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KLO14994.1 - 3.6e-06 26.5 21.3 7.3e-05 22.3 8.5 3.3 3 0 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KLO14994.1 - 7.1e-05 22.3 14.4 7.1e-05 22.3 10.0 3.1 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KLO14994.1 - 9.9e-05 22.0 16.0 9.9e-05 22.0 11.1 3.6 3 1 0 3 3 3 1 Ring finger domain zf-RING_5 PF14634.1 KLO14994.1 - 0.00023 20.8 12.8 0.00023 20.8 8.9 3.3 3 1 1 4 4 4 1 zinc-RING finger domain FUSC PF04632.7 KLO14994.1 - 0.017 13.5 1.5 0.024 13.1 1.1 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family HSA PF07529.8 KLO14994.1 - 0.88 9.3 6.9 0.72 9.6 1.3 2.6 2 0 0 2 2 2 0 HSA zf-Di19 PF05605.7 KLO14994.1 - 1.2 9.3 8.9 2.7 8.1 0.0 3.5 4 0 0 4 4 4 0 Drought induced 19 protein (Di19), zinc-binding Med2 PF11214.3 KLO14994.1 - 1.5 8.9 7.0 11 6.1 3.8 2.8 2 1 0 2 2 2 0 Mediator complex subunit 2 Acyl-thio_N PF12590.3 KLO14995.1 - 0.045 14.2 1.5 0.045 14.2 1.1 1.9 2 0 0 2 2 2 0 Acyl-ATP thioesterase Complex1_LYR PF05347.10 KLO14996.1 - 6.7e-10 38.6 2.8 1.1e-09 37.8 1.9 1.4 1 1 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 KLO14996.1 - 7.6e-09 35.6 1.2 1e-08 35.2 0.8 1.2 1 0 0 1 1 1 1 Complex1_LYR-like AFG1_ATPase PF03969.11 KLO14997.1 - 3e-101 338.8 0.1 3e-97 325.6 0.0 2.1 2 0 0 2 2 2 2 AFG1-like ATPase AAA_16 PF13191.1 KLO14997.1 - 3.2e-05 23.9 0.1 0.038 13.9 0.0 2.7 1 1 1 2 2 2 2 AAA ATPase domain AAA_22 PF13401.1 KLO14997.1 - 0.00016 21.8 0.1 0.001 19.2 0.0 2.3 2 1 0 2 2 2 1 AAA domain AAA PF00004.24 KLO14997.1 - 0.00028 21.0 0.0 0.00083 19.5 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) UvrD-helicase PF00580.16 KLO14997.1 - 0.037 13.3 0.0 0.19 10.9 0.0 2.1 2 1 1 3 3 3 0 UvrD/REP helicase N-terminal domain DUF2076 PF09849.4 KLO14997.1 - 0.095 12.7 0.0 0.16 11.9 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) JAB PF01398.16 KLO14998.1 - 3.2e-19 68.7 0.2 5.9e-19 67.8 0.1 1.4 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.1 KLO14998.1 - 4.1e-13 49.4 0.1 8e-13 48.4 0.0 1.4 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function DUF4533 PF15047.1 KLO14998.1 - 0.082 12.3 0.7 0.22 10.9 0.4 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF4533) Tom7 PF08038.7 KLO14999.1 - 4.3e-15 54.8 0.3 5.3e-15 54.5 0.2 1.1 1 0 0 1 1 1 1 TOM7 family rve PF00665.21 KLO15002.1 - 0.00096 19.2 0.0 0.0025 17.9 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain HTH_32 PF13565.1 KLO15002.1 - 0.0026 18.5 0.0 0.6 10.9 0.0 2.6 2 0 0 2 2 2 1 Homeodomain-like domain HTH_21 PF13276.1 KLO15002.1 - 0.0058 16.6 0.3 0.2 11.6 0.0 2.5 2 0 0 2 2 2 1 HTH-like domain HTH_Tnp_Tc3_2 PF01498.13 KLO15002.1 - 0.012 15.6 0.0 5.8 7.0 0.0 2.5 1 1 1 2 2 2 0 Transposase HTH_29 PF13551.1 KLO15002.1 - 0.055 13.6 0.0 0.5 10.5 0.0 2.2 1 1 1 2 2 2 0 Winged helix-turn helix Alpha_kinase PF02816.13 KLO15003.1 - 2.4e-10 40.3 0.3 4.8e-10 39.4 0.0 1.7 2 0 0 2 2 2 1 Alpha-kinase family FYVE_2 PF02318.11 KLO15003.1 - 0.73 9.7 10.3 28 4.6 7.1 2.4 1 1 0 1 1 1 0 FYVE-type zinc finger DnaJ_CXXCXGXG PF00684.14 KLO15003.1 - 2.3 8.3 8.0 5 7.2 5.6 1.6 1 0 0 1 1 1 0 DnaJ central domain DZR PF12773.2 KLO15003.1 - 3 7.7 9.1 11 5.9 5.8 2.3 1 1 1 2 2 2 0 Double zinc ribbon PBP1_TM PF14812.1 KLO15010.1 - 6.5 7.1 10.6 0.59 10.4 3.4 2.2 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DDE_3 PF13358.1 KLO15011.1 - 4.8e-09 36.1 0.0 7.7e-09 35.4 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_3 PF13358.1 KLO15012.1 - 8.2e-10 38.6 0.0 8.8e-10 38.5 0.0 1.0 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_33 PF13592.1 KLO15013.1 - 0.0012 18.2 0.0 0.0023 17.4 0.0 1.4 1 0 0 1 1 1 1 Winged helix-turn helix HTH_23 PF13384.1 KLO15013.1 - 0.079 12.6 0.1 0.16 11.6 0.1 1.6 1 0 0 1 1 1 0 Homeodomain-like domain ArgK PF03308.11 KLO15014.1 - 1.1 7.9 7.2 1.4 7.6 5.0 1.1 1 0 0 1 1 1 0 ArgK protein TPR_12 PF13424.1 KLO15015.1 - 7.7e-13 48.1 25.6 0.0025 17.7 0.8 6.9 6 2 2 8 8 8 4 Tetratricopeptide repeat SNAP PF14938.1 KLO15015.1 - 5.1e-07 29.1 14.1 0.00094 18.4 0.4 3.6 2 1 0 3 3 3 2 Soluble NSF attachment protein, SNAP TPR_11 PF13414.1 KLO15015.1 - 6.3e-07 28.9 21.1 0.16 11.6 0.8 5.7 3 2 3 6 6 6 5 TPR repeat AAA_16 PF13191.1 KLO15015.1 - 3.3e-06 27.2 1.4 0.00018 21.5 0.9 3.1 1 1 0 1 1 1 1 AAA ATPase domain NB-ARC PF00931.17 KLO15015.1 - 9.2e-06 24.7 0.0 2e-05 23.6 0.0 1.6 1 0 0 1 1 1 1 NB-ARC domain TPR_2 PF07719.12 KLO15015.1 - 0.0027 17.4 25.0 0.83 9.7 0.0 7.3 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_8 PF13181.1 KLO15015.1 - 0.0084 15.8 9.6 2 8.4 0.4 5.6 5 0 0 5 5 5 1 Tetratricopeptide repeat AAA_22 PF13401.1 KLO15015.1 - 0.013 15.6 0.0 0.06 13.4 0.0 2.2 1 0 0 1 1 1 0 AAA domain DUF2225 PF09986.4 KLO15015.1 - 0.021 14.3 0.4 0.24 10.8 0.1 2.6 2 1 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2225) AAA_25 PF13481.1 KLO15015.1 - 0.031 13.6 0.0 0.07 12.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain TPR_10 PF13374.1 KLO15015.1 - 6.5 6.8 10.5 3.7 7.6 0.1 4.7 4 1 1 5 5 5 0 Tetratricopeptide repeat PMM PF03332.8 KLO15016.1 - 3e-79 265.6 0.0 3.7e-79 265.3 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic phosphomannomutase Hydrolase_3 PF08282.7 KLO15016.1 - 0.00028 20.5 0.0 0.19 11.2 0.0 2.2 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase zf-MYND PF01753.13 KLO15017.1 - 3.1e-08 33.3 11.5 3.1e-08 33.3 8.0 1.9 2 0 0 2 2 2 1 MYND finger zf-MYND PF01753.13 KLO15018.1 - 1e-07 31.7 11.4 1.8e-07 30.8 7.9 1.4 1 0 0 1 1 1 1 MYND finger DUF89 PF01937.14 KLO15019.1 - 1.5e-105 352.9 0.0 1.7e-105 352.7 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function DUF89 GVQW PF13900.1 KLO15021.1 - 0.16 11.9 0.3 0.29 11.1 0.1 1.5 2 0 0 2 2 2 0 Putative binding domain TPR_12 PF13424.1 KLO15022.1 - 3e-08 33.5 31.9 0.00088 19.1 0.4 7.6 6 1 3 9 9 9 4 Tetratricopeptide repeat NB-ARC PF00931.17 KLO15022.1 - 3.9e-05 22.6 0.1 0.0001 21.3 0.0 1.7 2 0 0 2 2 2 1 NB-ARC domain SNAP PF14938.1 KLO15022.1 - 0.00016 20.9 13.6 0.024 13.7 0.1 3.3 3 0 0 3 3 3 2 Soluble NSF attachment protein, SNAP AAA_16 PF13191.1 KLO15022.1 - 0.00019 21.4 0.9 0.00048 20.1 0.1 2.1 2 0 0 2 2 2 1 AAA ATPase domain TPR_11 PF13414.1 KLO15022.1 - 0.00035 20.1 15.1 0.03 13.9 0.0 5.2 4 1 1 5 5 5 3 TPR repeat TPR_2 PF07719.12 KLO15022.1 - 0.005 16.6 21.1 0.88 9.6 0.0 7.0 7 0 0 7 7 7 2 Tetratricopeptide repeat AAA_22 PF13401.1 KLO15022.1 - 0.0059 16.7 0.0 0.023 14.8 0.0 2.0 1 0 0 1 1 1 1 AAA domain NACHT PF05729.7 KLO15022.1 - 0.014 15.0 0.0 0.052 13.2 0.0 2.0 2 0 0 2 2 2 0 NACHT domain DUF3856 PF12968.2 KLO15022.1 - 0.024 14.4 0.3 0.13 12.0 0.1 2.3 2 0 0 2 2 2 0 Domain of Unknown Function (DUF3856) Asp PF00026.18 KLO15024.1 - 1.7e-48 165.5 7.9 3.9e-48 164.3 5.4 1.5 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 KLO15024.1 - 7.9e-08 32.4 4.2 2e-06 27.8 1.4 3.5 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 KLO15024.1 - 0.0033 17.8 2.5 0.05 14.0 0.5 2.7 2 0 0 2 2 2 1 Aspartyl protease TAXi_C PF14541.1 KLO15024.1 - 0.043 13.3 0.9 0.17 11.3 0.1 2.3 2 1 0 2 2 2 0 Xylanase inhibitor C-terminal ABC_tran PF00005.22 KLO15025.1 - 1.2e-47 161.6 0.0 5.4e-28 98.0 0.0 2.5 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 KLO15025.1 - 1.7e-43 149.0 25.2 2.1e-27 96.2 3.7 2.3 2 0 0 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.14 KLO15025.1 - 9.3e-08 31.5 2.5 0.014 14.6 0.0 4.2 2 2 1 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_25 PF13481.1 KLO15025.1 - 1.6e-07 30.9 0.2 0.0045 16.4 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.1 KLO15025.1 - 1.9e-06 28.0 1.3 0.057 13.4 0.2 2.9 2 0 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.1 KLO15025.1 - 2.8e-06 26.7 2.2 0.002 17.6 0.1 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain T2SE PF00437.15 KLO15025.1 - 7.8e-06 24.9 3.5 0.04 12.8 0.2 2.5 2 0 0 2 2 2 2 Type II/IV secretion system protein DUF87 PF01935.12 KLO15025.1 - 8.6e-06 25.7 5.2 0.032 14.0 0.5 2.4 2 0 0 2 2 2 2 Domain of unknown function DUF87 AAA_17 PF13207.1 KLO15025.1 - 4.7e-05 24.1 0.2 0.22 12.3 0.1 3.1 2 0 0 2 2 2 2 AAA domain AAA_23 PF13476.1 KLO15025.1 - 6.4e-05 23.3 1.0 0.01 16.1 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_21 PF13304.1 KLO15025.1 - 0.00014 21.9 8.2 2.9 7.7 0.0 4.7 3 2 0 4 4 3 2 AAA domain AAA_18 PF13238.1 KLO15025.1 - 0.0002 21.6 0.6 0.72 10.1 0.4 2.8 2 0 0 2 2 2 2 AAA domain Dynamin_N PF00350.18 KLO15025.1 - 0.00025 20.9 0.2 0.025 14.3 0.0 2.4 2 0 0 2 2 2 1 Dynamin family MobB PF03205.9 KLO15025.1 - 0.00046 19.9 1.7 0.053 13.2 0.2 2.5 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B FtsK_SpoIIIE PF01580.13 KLO15025.1 - 0.00068 19.1 0.0 0.51 9.7 0.0 2.6 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA_19 PF13245.1 KLO15025.1 - 0.0014 18.3 4.9 0.044 13.5 0.1 3.8 4 0 0 4 4 3 1 Part of AAA domain NACHT PF05729.7 KLO15025.1 - 0.0018 17.9 1.2 1.5 8.4 0.0 2.8 2 0 0 2 2 2 2 NACHT domain AAA_30 PF13604.1 KLO15025.1 - 0.0024 17.4 0.0 0.42 10.1 0.0 2.8 2 1 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.18 KLO15025.1 - 0.0026 17.7 0.0 3.5 7.5 0.0 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_10 PF12846.2 KLO15025.1 - 0.0039 16.6 1.6 2 7.7 0.0 2.8 3 0 0 3 3 3 2 AAA-like domain AAA_22 PF13401.1 KLO15025.1 - 0.0041 17.2 5.4 2.7 8.1 1.7 3.2 2 1 0 2 2 2 1 AAA domain AAA_33 PF13671.1 KLO15025.1 - 0.0066 16.3 0.0 4.1 7.2 0.0 2.8 2 0 0 2 2 2 0 AAA domain Miro PF08477.8 KLO15025.1 - 0.01 16.3 2.8 2 8.9 0.1 2.7 2 0 0 2 2 2 0 Miro-like protein TrwB_AAD_bind PF10412.4 KLO15025.1 - 0.015 13.9 3.4 0.84 8.1 0.1 2.8 3 0 0 3 3 3 0 Type IV secretion-system coupling protein DNA-binding domain Pox_A32 PF04665.7 KLO15025.1 - 0.023 13.9 0.6 1.2 8.3 0.1 2.4 2 0 0 2 2 2 0 Poxvirus A32 protein DUF2075 PF09848.4 KLO15025.1 - 0.023 13.6 3.0 1.1 8.1 0.0 3.1 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2075) ResIII PF04851.10 KLO15025.1 - 0.028 14.2 0.0 5.4 6.8 0.0 2.5 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit AAA PF00004.24 KLO15025.1 - 0.041 14.0 0.1 12 6.1 0.0 3.6 3 1 0 3 3 2 0 ATPase family associated with various cellular activities (AAA) CbiA PF01656.18 KLO15025.1 - 0.055 12.8 0.1 1.1 8.6 0.0 2.5 2 0 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain DEAD PF00270.24 KLO15025.1 - 0.076 12.5 0.1 2.6 7.5 0.0 2.7 2 1 0 2 2 2 0 DEAD/DEAH box helicase Zeta_toxin PF06414.7 KLO15025.1 - 0.088 11.8 2.6 5.7 5.9 0.2 2.5 2 0 0 2 2 2 0 Zeta toxin SRP54 PF00448.17 KLO15025.1 - 0.17 11.3 0.6 0.66 9.3 0.0 2.1 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain cobW PF02492.14 KLO15025.1 - 0.23 10.9 4.1 5.8 6.3 0.1 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain DUF258 PF03193.11 KLO15025.1 - 0.32 10.1 0.3 3.6 6.7 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function, DUF258 Viral_helicase1 PF01443.13 KLO15025.1 - 0.36 10.3 1.5 4.8 6.6 0.0 2.5 3 0 0 3 3 2 0 Viral (Superfamily 1) RNA helicase NTPase_1 PF03266.10 KLO15025.1 - 1.8 8.2 4.7 3.9 7.1 0.2 2.7 3 0 0 3 3 2 0 NTPase Aldedh PF00171.17 KLO15026.1 - 1.1e-121 406.4 0.0 1.3e-121 406.2 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Ribonuclease_T2 PF00445.13 KLO15027.1 - 1.9e-40 138.4 0.1 2.7e-40 138.0 0.0 1.1 1 0 0 1 1 1 1 Ribonuclease T2 family ACT_7 PF13840.1 KLO15029.1 - 9.5e-19 66.6 0.0 1.7e-18 65.8 0.0 1.4 1 0 0 1 1 1 1 ACT domain Mito_carr PF00153.22 KLO15030.1 - 1.9e-56 187.7 0.4 3.8e-19 68.2 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein PXA PF02194.10 KLO15031.1 - 7.6e-42 142.9 0.7 1.8e-41 141.7 0.0 2.0 3 0 0 3 3 3 1 PXA domain Nexin_C PF08628.7 KLO15031.1 - 9e-30 103.0 0.0 4e-29 100.9 0.0 2.2 1 0 0 1 1 1 1 Sorting nexin C terminal PX PF00787.19 KLO15031.1 - 1.5e-15 56.9 0.0 3.9e-15 55.6 0.0 1.7 1 0 0 1 1 1 1 PX domain RGS PF00615.14 KLO15031.1 - 4.3e-09 36.4 0.1 9.8e-09 35.3 0.1 1.7 1 0 0 1 1 1 1 Regulator of G protein signaling domain Isy1 PF06246.7 KLO15031.1 - 0.0049 16.3 0.1 0.016 14.6 0.1 1.8 1 0 0 1 1 1 1 Isy1-like splicing family Prenyltrans PF00432.16 KLO15031.1 - 0.018 14.6 0.0 0.19 11.3 0.0 2.4 2 0 0 2 2 2 0 Prenyltransferase and squalene oxidase repeat MgtC PF02308.11 KLO15033.1 - 0.034 13.9 0.5 0.13 12.0 0.0 1.8 2 0 0 2 2 2 0 MgtC family Fer4_21 PF14697.1 KLO15033.1 - 0.041 13.7 0.9 0.092 12.6 0.7 1.6 1 0 0 1 1 1 0 4Fe-4S dicluster domain CBM_21 PF03370.8 KLO15034.1 - 1.5e-21 76.5 0.0 7.1e-10 38.8 0.0 2.3 2 0 0 2 2 2 2 Putative phosphatase regulatory subunit CryBP1 PF07029.6 KLO15035.1 - 0.047 13.4 0.1 0.067 12.9 0.0 1.2 1 0 0 1 1 1 0 CryBP1 protein Pacifastin_I PF05375.8 KLO15037.1 - 0.046 13.2 1.3 0.068 12.6 0.1 2.0 2 0 0 2 2 2 0 Pacifastin inhibitor (LCMII) Polysacc_deac_1 PF01522.16 KLO15038.1 - 4.5e-06 26.3 0.1 1.5e-05 24.6 0.0 1.9 1 1 0 1 1 1 1 Polysaccharide deacetylase DUF148 PF02520.12 KLO15039.1 - 0.14 12.0 1.6 0.28 10.9 1.1 1.4 1 0 0 1 1 1 0 Domain of unknown function DUF148 Myosin_head PF00063.16 KLO15040.1 - 8.6e-227 754.4 0.6 1.3e-226 753.8 0.4 1.3 1 0 0 1 1 1 1 Myosin head (motor domain) Myosin_TH1 PF06017.8 KLO15040.1 - 6.4e-44 149.6 0.0 1.3e-43 148.6 0.0 1.6 1 0 0 1 1 1 1 Myosin tail UNC45-central PF11701.3 KLO15040.1 - 1.5e-16 60.4 0.1 3.7e-16 59.1 0.0 1.8 1 0 0 1 1 1 1 Myosin-binding striated muscle assembly central SH3_2 PF07653.12 KLO15040.1 - 5.6e-10 38.5 0.0 1.3e-09 37.4 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.1 KLO15040.1 - 7.6e-09 35.0 0.2 2e-08 33.7 0.2 1.8 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 KLO15040.1 - 9.6e-09 34.5 1.0 1.9e-08 33.5 0.7 1.5 1 0 0 1 1 1 1 SH3 domain SH3_3 PF08239.6 KLO15040.1 - 0.00028 21.0 0.7 0.00065 19.8 0.5 1.6 1 0 0 1 1 1 1 Bacterial SH3 domain AAA_22 PF13401.1 KLO15040.1 - 0.0093 16.1 0.0 0.028 14.5 0.0 1.8 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 KLO15040.1 - 0.035 13.2 0.0 0.097 11.7 0.0 1.7 1 0 0 1 1 1 0 Zeta toxin Hpr_kinase_C PF07475.7 KLO15040.1 - 0.036 13.3 0.7 6.4 6.0 0.0 2.5 2 0 0 2 2 2 0 HPr Serine kinase C-terminal domain AAA_17 PF13207.1 KLO15040.1 - 0.1 13.4 0.0 0.32 11.8 0.0 1.9 1 0 0 1 1 1 0 AAA domain DUF229 PF02995.12 KLO15040.1 - 0.11 10.8 0.0 0.21 9.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF229) HEAT PF02985.17 KLO15040.1 - 0.14 12.3 1.0 1.6 9.0 0.1 3.1 2 0 0 2 2 2 0 HEAT repeat Gcd10p PF04189.8 KLO15041.1 - 9.8e-69 231.7 0.0 9.2e-68 228.5 0.0 2.0 1 1 0 1 1 1 1 Gcd10p family GDI PF00996.13 KLO15042.1 - 1.6e-208 692.4 0.3 1.8e-208 692.2 0.2 1.0 1 0 0 1 1 1 1 GDP dissociation inhibitor Methyltransf_11 PF08241.7 KLO15043.1 - 1.8e-12 47.6 0.0 4.6e-12 46.2 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KLO15043.1 - 3.2e-11 43.2 0.0 1.8e-10 40.7 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 KLO15043.1 - 7.7e-09 35.8 0.0 2e-08 34.4 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KLO15043.1 - 2.8e-08 33.1 0.0 4.6e-08 32.4 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_18 PF12847.2 KLO15043.1 - 1.1e-07 32.4 0.0 4e-07 30.5 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 KLO15043.1 - 7.7e-07 29.5 0.0 2.6e-06 27.8 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KLO15043.1 - 3.5e-06 26.6 0.0 7.2e-06 25.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KLO15043.1 - 4e-06 26.8 0.0 1.1e-05 25.4 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.14 KLO15043.1 - 0.0002 21.3 0.0 0.00034 20.6 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_4 PF02390.12 KLO15043.1 - 0.00027 20.0 0.0 0.0053 15.8 0.0 2.3 2 0 0 2 2 2 1 Putative methyltransferase Methyltransf_2 PF00891.13 KLO15043.1 - 0.0031 16.7 0.0 0.0057 15.8 0.0 1.4 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_29 PF03141.11 KLO15043.1 - 0.012 14.0 0.0 0.024 12.9 0.0 1.4 2 0 0 2 2 2 0 Putative S-adenosyl-L-methionine-dependent methyltransferase MTS PF05175.9 KLO15043.1 - 0.022 14.1 0.0 0.046 13.1 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase small domain CMAS PF02353.15 KLO15043.1 - 0.16 11.0 0.0 0.28 10.2 0.0 1.3 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Rav1p_C PF12234.3 KLO15044.1 - 1.1e-178 595.3 0.0 2.8e-178 594.0 0.0 1.6 1 1 0 1 1 1 1 RAVE protein 1 C terminal Fasciclin PF02469.17 KLO15045.1 - 3.7e-65 217.7 0.0 1.9e-15 57.0 0.0 5.4 5 0 0 5 5 5 5 Fasciclin domain SprB PF13573.1 KLO15045.1 - 0.13 11.9 2.2 0.15 11.6 0.3 2.0 2 0 0 2 2 2 0 SprB repeat Acetyltransf_7 PF13508.1 KLO15046.1 - 3.7e-07 30.2 0.0 6.8e-07 29.3 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 KLO15046.1 - 1.5e-05 25.1 0.0 2.5e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 KLO15046.1 - 0.00022 21.1 0.0 0.00038 20.4 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.5 KLO15046.1 - 0.0072 16.0 0.0 0.013 15.2 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.1 KLO15046.1 - 0.0081 16.0 0.0 0.014 15.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain p450 PF00067.17 KLO15048.1 - 5.4e-75 252.6 0.0 6.1e-75 252.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF2435 PF10363.4 KLO15049.1 - 0.019 14.8 0.0 0.096 12.5 0.0 2.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2435) HEAT_2 PF13646.1 KLO15049.1 - 0.1 12.9 1.5 27 5.1 0.0 4.3 3 1 0 3 3 3 0 HEAT repeats NAP PF00956.13 KLO15049.1 - 0.29 10.2 0.3 0.54 9.3 0.2 1.3 1 0 0 1 1 1 0 Nucleosome assembly protein (NAP) dCMP_cyt_deam_1 PF00383.17 KLO15050.1 - 1.5e-24 85.5 2.0 2.4e-24 84.8 1.4 1.3 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region AAA_17 PF13207.1 KLO15050.1 - 0.0029 18.4 0.0 0.0081 16.9 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.1 KLO15050.1 - 0.029 14.2 0.1 0.092 12.6 0.0 1.9 1 1 1 2 2 2 0 AAA domain AAA_33 PF13671.1 KLO15050.1 - 0.049 13.5 0.0 0.081 12.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.1 KLO15050.1 - 0.095 12.2 0.0 0.22 11.0 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_18 PF13238.1 KLO15050.1 - 0.16 12.3 0.0 0.36 11.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain PhzC-PhzF PF02567.11 KLO15051.1 - 3.9e-47 160.7 0.0 4.6e-47 160.5 0.0 1.0 1 0 0 1 1 1 1 Phenazine biosynthesis-like protein UQ_con PF00179.21 KLO15052.1 - 1.2e-20 73.3 0.0 2.1e-20 72.6 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme DUF4537 PF15057.1 KLO15052.1 - 0.0097 15.6 0.2 0.13 12.0 0.0 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF4537) UEV PF05743.8 KLO15052.1 - 0.078 12.6 0.0 0.18 11.4 0.0 1.6 1 0 0 1 1 1 0 UEV domain Nop14 PF04147.7 KLO15052.1 - 3.3 5.5 16.5 5.1 4.8 11.5 1.2 1 0 0 1 1 1 0 Nop14-like family SKN1 PF03935.10 KLO15053.1 - 6e-192 638.2 1.1 7.7e-192 637.9 0.8 1.1 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) DUF619 PF04768.8 KLO15055.1 - 4.9e-37 126.9 0.1 3e-22 78.8 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF619) AA_kinase PF00696.23 KLO15055.1 - 0.00079 19.0 0.0 0.0014 18.2 0.0 1.3 1 0 0 1 1 1 1 Amino acid kinase family Mito_carr PF00153.22 KLO15056.1 - 3.3e-67 222.2 7.1 5.6e-22 77.2 0.2 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein PP2C PF00481.16 KLO15057.1 - 1e-22 80.7 0.0 3.8e-21 75.6 0.0 2.4 2 1 0 2 2 2 1 Protein phosphatase 2C PP2C_2 PF13672.1 KLO15057.1 - 1.7e-08 34.1 0.0 3.8e-08 33.0 0.0 1.6 1 1 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.7 KLO15057.1 - 6e-07 29.3 0.0 0.017 14.8 0.0 2.6 2 0 0 2 2 2 2 Stage II sporulation protein E (SpoIIE) MMR_HSR1 PF01926.18 KLO15058.1 - 2.7e-15 56.3 0.0 7.8e-15 54.8 0.0 1.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.13 KLO15058.1 - 2.2e-07 30.2 0.0 3.6e-07 29.5 0.0 1.3 1 0 0 1 1 1 1 Ferrous iron transport protein B DUF258 PF03193.11 KLO15058.1 - 0.00023 20.4 0.0 0.0004 19.5 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Dynamin_N PF00350.18 KLO15058.1 - 0.0016 18.2 2.4 0.04 13.7 0.1 3.1 3 1 1 4 4 4 1 Dynamin family Miro PF08477.8 KLO15058.1 - 0.0069 16.8 0.0 0.018 15.5 0.0 1.7 1 0 0 1 1 1 1 Miro-like protein AIG1 PF04548.11 KLO15058.1 - 0.024 13.7 0.0 0.11 11.6 0.0 1.9 2 0 0 2 2 2 0 AIG1 family Septin PF00735.13 KLO15058.1 - 0.15 11.0 0.0 0.97 8.3 0.0 2.1 2 0 0 2 2 2 0 Septin BCL_N PF04714.8 KLO15059.1 - 0.0079 15.7 0.1 0.013 15.0 0.1 1.3 1 0 0 1 1 1 1 BCL7, N-terminal conserver region MRP-S25 PF13741.1 KLO15060.1 - 3.2e-42 144.5 3.7 1.8e-41 142.1 2.6 1.9 1 1 0 1 1 1 1 Mitochondrial ribosomal protein S25 DUF4510 PF14971.1 KLO15060.1 - 0.045 13.9 0.4 0.045 13.9 0.3 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4510) ICL PF00463.16 KLO15061.1 - 2.9e-187 623.0 0.1 3.4e-187 622.8 0.1 1.0 1 0 0 1 1 1 1 Isocitrate lyase family PEP_mutase PF13714.1 KLO15061.1 - 1.1e-10 41.1 1.6 2.3e-10 40.1 0.0 2.2 3 0 0 3 3 3 1 Phosphoenolpyruvate phosphomutase Tox-REase-2 PF15646.1 KLO15061.1 - 0.093 12.6 0.4 0.23 11.3 0.2 1.7 2 0 0 2 2 2 0 Restriction endonuclease fold toxin 2 Med11 PF10280.4 KLO15062.1 - 2.2e-07 30.9 0.2 3.8e-07 30.1 0.2 1.4 1 0 0 1 1 1 1 Mediator complex protein TBCA PF02970.11 KLO15063.1 - 3.9e-11 42.8 12.4 8.5e-11 41.7 8.4 1.7 1 1 1 2 2 2 1 Tubulin binding cofactor A Reo_sigmaC PF04582.7 KLO15063.1 - 0.0012 18.0 1.2 0.0014 17.8 0.8 1.0 1 0 0 1 1 1 1 Reovirus sigma C capsid protein DUF1664 PF07889.7 KLO15063.1 - 0.044 13.5 4.3 0.071 12.9 3.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Med11 PF10280.4 KLO15063.1 - 0.048 13.7 4.8 0.076 13.0 3.3 1.3 1 0 0 1 1 1 0 Mediator complex protein DUF641 PF04859.7 KLO15063.1 - 0.051 13.3 0.7 0.051 13.3 0.5 2.1 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) FliJ PF02050.11 KLO15063.1 - 0.07 13.1 7.2 0.094 12.7 5.0 1.1 1 0 0 1 1 1 0 Flagellar FliJ protein Telomere_reg-2 PF10193.4 KLO15063.1 - 0.074 13.3 0.8 0.11 12.7 0.4 1.5 1 1 0 1 1 1 0 Telomere length regulation protein Spectrin PF00435.16 KLO15063.1 - 0.077 13.2 3.1 0.11 12.7 1.7 1.7 1 1 1 2 2 2 0 Spectrin repeat FliD_N PF02465.13 KLO15063.1 - 0.19 12.1 1.8 0.39 11.1 1.2 1.6 1 1 0 1 1 1 0 Flagellar hook-associated protein 2 N-terminus Val_tRNA-synt_C PF10458.4 KLO15063.1 - 0.27 11.3 5.1 0.19 11.8 1.6 2.4 2 1 0 2 2 2 0 Valyl tRNA synthetase tRNA binding arm SlyX PF04102.7 KLO15063.1 - 0.32 11.3 3.0 6.5 7.2 0.2 2.3 1 1 1 2 2 2 0 SlyX Syntaxin-6_N PF09177.6 KLO15063.1 - 0.62 10.5 4.5 0.46 10.9 1.5 1.8 1 1 1 2 2 2 0 Syntaxin 6, N-terminal ICA69 PF04629.9 KLO15063.1 - 0.83 9.5 4.8 0.98 9.3 3.4 1.1 1 0 0 1 1 1 0 Islet cell autoantigen ICA69, C-terminal domain TPR_MLP1_2 PF07926.7 KLO15063.1 - 0.93 9.2 10.7 0.27 10.9 4.9 1.8 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein Exonuc_VII_L PF02601.10 KLO15063.1 - 0.95 8.5 6.5 1.1 8.3 4.5 1.0 1 0 0 1 1 1 0 Exonuclease VII, large subunit PhoU PF01895.14 KLO15063.1 - 1.2 9.6 4.3 0.85 10.1 0.9 2.1 2 1 0 2 2 2 0 PhoU domain HLH PF00010.21 KLO15066.1 - 9.7e-10 38.0 4.8 2.5e-09 36.6 1.1 2.4 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain EF-1_beta_acid PF10587.4 KLO15066.1 - 9.8 6.4 8.3 30 4.8 5.7 1.8 1 0 0 1 1 1 0 Eukaryotic elongation factor 1 beta central acidic region 5TM-5TMR_LYT PF07694.7 KLO15067.1 - 0.34 10.2 9.4 0.95 8.7 4.3 2.0 2 0 0 2 2 2 0 5TMR of 5TMR-LYT HLH PF00010.21 KLO15068.1 - 8e-11 41.4 1.3 8e-11 41.4 0.9 2.3 2 1 0 2 2 2 1 Helix-loop-helix DNA-binding domain CENP-F_leu_zip PF10473.4 KLO15068.1 - 0.12 12.2 2.9 0.21 11.4 2.0 1.4 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF342 PF03961.8 KLO15068.1 - 0.34 9.2 1.6 0.47 8.7 1.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) IncA PF04156.9 KLO15068.1 - 6.7 6.2 6.9 26 4.3 4.8 1.9 1 1 0 1 1 1 0 IncA protein Het-C PF07217.6 KLO15069.1 - 2.6e-05 22.6 0.1 5e-05 21.7 0.1 1.4 1 1 1 2 2 2 1 Heterokaryon incompatibility protein Het-C PRD PF00874.15 KLO15069.1 - 0.015 15.3 0.1 0.052 13.6 0.0 2.0 2 1 0 2 2 2 0 PRD domain DnaJ PF00226.26 KLO15070.1 - 2.9e-09 36.5 0.0 7.1e-09 35.2 0.0 1.6 1 0 0 1 1 1 1 DnaJ domain TPR_2 PF07719.12 KLO15070.1 - 0.027 14.3 0.1 0.12 12.3 0.1 2.2 1 0 0 1 1 1 0 Tetratricopeptide repeat DUF4398 PF14346.1 KLO15070.1 - 0.035 14.1 0.5 0.035 14.1 0.3 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4398) DnaJ PF00226.26 KLO15071.1 - 7.8e-09 35.1 0.0 3.3e-08 33.1 0.0 2.2 1 0 0 1 1 1 1 DnaJ domain Asp-B-Hydro_N PF05279.6 KLO15071.1 - 2.7 7.7 22.3 5.1 6.8 15.4 1.4 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Peptidase_S46 PF10459.4 KLO15071.1 - 2.8 6.2 26.4 4.2 5.6 18.3 1.2 1 0 0 1 1 1 0 Peptidase S46 Het-C PF07217.6 KLO15072.1 - 1.3e-197 657.7 0.0 1.8e-196 653.9 0.0 2.4 1 1 0 1 1 1 1 Heterokaryon incompatibility protein Het-C ApbA_C PF08546.6 KLO15073.1 - 2.9e-33 114.5 0.0 4.3e-33 113.9 0.0 1.2 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.11 KLO15073.1 - 3e-15 55.9 0.0 5.3e-15 55.1 0.0 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Aldo_ket_red PF00248.16 KLO15074.1 - 1.5e-45 155.2 0.0 1.7e-45 155.0 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family ATXN-1_C PF12547.3 KLO15075.1 - 0.7 9.9 4.8 2.1 8.3 0.3 2.7 3 0 0 3 3 3 0 Capicua transcriptional repressor modulator RNase_T PF00929.19 KLO15076.1 - 1.8e-08 34.8 0.2 3e-08 34.1 0.1 1.3 1 0 0 1 1 1 1 Exonuclease LSM PF01423.17 KLO15082.1 - 9.7e-17 60.2 0.3 1.5e-16 59.7 0.0 1.4 2 0 0 2 2 2 1 LSM domain tRNA-synt_2 PF00152.15 KLO15083.1 - 8.1e-73 245.0 0.0 1.1e-72 244.6 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 KLO15083.1 - 4.6e-10 39.2 0.0 9.9e-10 38.1 0.0 1.6 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain Toxin_52 PF15605.1 KLO15083.1 - 0.05 13.5 0.3 1.3 8.9 0.0 2.6 2 1 1 3 3 3 0 Putative toxin 52 TP_methylase PF00590.15 KLO15084.1 - 3.4e-18 66.1 0.0 5.2e-18 65.5 0.0 1.3 1 0 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases Evr1_Alr PF04777.8 KLO15085.1 - 8.1e-27 92.9 0.6 1.2e-26 92.4 0.4 1.2 1 0 0 1 1 1 1 Erv1 / Alr family Spore_III_AF PF09581.5 KLO15085.1 - 0.14 12.0 0.0 0.2 11.5 0.0 1.2 1 0 0 1 1 1 0 Stage III sporulation protein AF (Spore_III_AF) Glyco_hydro_71 PF03659.9 KLO15086.1 - 1.4e-88 296.9 0.1 1.7e-88 296.6 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 71 Dynamin_N PF00350.18 KLO15087.1 - 2.2e-07 30.8 0.0 7.7e-07 29.0 0.0 1.9 1 1 0 1 1 1 1 Dynamin family DUF3847 PF12958.2 KLO15089.1 - 0.18 11.5 1.2 0.36 10.6 0.3 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3847) Pantoate_transf PF02548.10 KLO15090.1 - 1e-108 362.4 0.1 1.2e-108 362.2 0.1 1.0 1 0 0 1 1 1 1 Ketopantoate hydroxymethyltransferase PEP_mutase PF13714.1 KLO15090.1 - 1.7e-09 37.2 0.8 1.2e-07 31.2 0.1 2.4 1 1 1 2 2 2 2 Phosphoenolpyruvate phosphomutase Sulfate_transp PF00916.15 KLO15092.1 - 4.1e-59 199.8 10.6 4.1e-59 199.8 7.3 2.1 2 1 1 3 3 3 1 Sulfate transporter family Sulfate_tra_GLY PF13792.1 KLO15092.1 - 8.6e-22 76.6 3.7 8.6e-22 76.6 2.6 2.9 3 0 0 3 3 3 1 Sulfate transporter N-terminal domain with GLY motif STAS PF01740.16 KLO15092.1 - 6.9e-16 57.7 0.0 1.2e-15 56.9 0.0 1.4 1 0 0 1 1 1 1 STAS domain STAS_2 PF13466.1 KLO15092.1 - 0.00062 19.7 0.1 0.0028 17.6 0.0 2.2 2 0 0 2 2 2 1 STAS domain F-box-like PF12937.2 KLO15093.1 - 2.8e-08 33.3 0.0 7.2e-08 32.0 0.0 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KLO15093.1 - 0.16 11.7 3.9 8.3 6.1 0.0 3.0 3 0 0 3 3 3 0 F-box domain F-box-like PF12937.2 KLO15094.1 - 8.4e-07 28.6 0.1 2.3e-06 27.2 0.0 1.8 1 0 0 1 1 1 1 F-box-like DUF3254 PF11630.3 KLO15094.1 - 0.014 15.3 0.2 0.044 13.7 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3254) F-box-like_2 PF13013.1 KLO15094.1 - 0.049 13.3 0.0 0.11 12.2 0.0 1.7 1 0 0 1 1 1 0 F-box-like domain CENP-B_dimeris PF09026.5 KLO15097.1 - 0.72 10.1 8.3 0.23 11.7 0.4 2.9 3 0 0 3 3 3 0 Centromere protein B dimerisation domain Nucleoplasmin PF03066.10 KLO15097.1 - 8.6 5.8 14.2 8.4 5.8 5.5 2.5 2 0 0 2 2 2 0 Nucleoplasmin zf-MYND PF01753.13 KLO15098.1 - 8.1e-08 32.0 16.4 2.1e-07 30.6 11.4 1.7 1 0 0 1 1 1 1 MYND finger DUF4277 PF14104.1 KLO15098.1 - 0.071 13.3 0.0 7 6.8 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4277) zf-Mss51 PF13824.1 KLO15098.1 - 0.092 12.6 8.3 0.2 11.5 5.8 1.5 1 0 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 BTB PF00651.26 KLO15099.1 - 6.7e-10 38.9 0.0 9.1e-10 38.5 0.0 1.2 1 0 0 1 1 1 1 BTB/POZ domain Sulfate_transp PF00916.15 KLO15100.1 - 4.9e-45 153.6 9.9 4.9e-45 153.6 6.9 1.5 2 0 0 2 2 2 1 Sulfate transporter family Sulfate_tra_GLY PF13792.1 KLO15100.1 - 1.4e-19 69.5 4.5 1.4e-19 69.5 3.1 2.7 3 0 0 3 3 3 1 Sulfate transporter N-terminal domain with GLY motif STAS PF01740.16 KLO15100.1 - 1.3e-16 60.0 0.0 2.7e-16 59.0 0.0 1.5 1 0 0 1 1 1 1 STAS domain DUF4124 PF13511.1 KLO15100.1 - 0.0081 16.1 0.0 0.018 15.0 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4124) STAS_2 PF13466.1 KLO15100.1 - 0.036 14.0 0.2 0.17 11.9 0.1 2.2 1 1 0 1 1 1 0 STAS domain GDE_C PF06202.9 KLO15101.1 - 0.00032 19.5 0.1 0.083 11.5 0.0 2.4 2 1 0 2 2 2 2 Amylo-alpha-1,6-glucosidase F-box-like PF12937.2 KLO15103.1 - 7.7e-07 28.7 0.1 1.9e-06 27.5 0.1 1.7 1 0 0 1 1 1 1 F-box-like Glutaredoxin2_C PF04399.8 KLO15104.1 - 0.13 11.8 0.0 0.28 10.7 0.0 1.6 2 0 0 2 2 2 0 Glutaredoxin 2, C terminal domain F-box-like PF12937.2 KLO15105.1 - 7.4e-07 28.8 0.0 2.2e-06 27.2 0.0 1.9 1 0 0 1 1 1 1 F-box-like F-box-like PF12937.2 KLO15106.1 - 9.3e-06 25.2 0.2 2.4e-05 23.9 0.1 1.8 1 0 0 1 1 1 1 F-box-like DUF3254 PF11630.3 KLO15106.1 - 0.012 15.5 0.0 0.034 14.1 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3254) F-box PF00646.28 KLO15106.1 - 0.057 13.0 2.9 8.8 6.1 0.0 3.0 3 0 0 3 3 3 0 F-box domain BTB PF00651.26 KLO15107.1 - 1.3e-06 28.4 0.0 3e-06 27.1 0.0 1.6 1 1 0 1 1 1 1 BTB/POZ domain BTB PF00651.26 KLO15108.1 - 5.5e-05 23.1 0.0 9.2e-05 22.3 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain Glyco_tranf_2_5 PF13712.1 KLO15108.1 - 0.11 11.6 0.0 0.16 11.1 0.0 1.2 1 0 0 1 1 1 0 Glycosyltransferase like family Trp_oprn_chp PF09534.5 KLO15109.1 - 0.052 13.1 0.1 0.12 11.9 0.1 1.5 1 0 0 1 1 1 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) CopD PF05425.8 KLO15109.1 - 0.1 12.8 6.7 5.4 7.2 1.3 3.2 3 1 0 3 3 3 0 Copper resistance protein D TMEM18 PF14770.1 KLO15109.1 - 6.1 6.4 10.2 0.16 11.4 0.9 2.6 3 0 0 3 3 3 0 Transmembrane protein 18 DUF2263 PF10021.4 KLO15111.1 - 1.3e-31 109.6 0.0 8.3e-31 106.9 0.0 2.0 1 1 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2263) DUF2263 PF10021.4 KLO15112.1 - 9.7e-27 93.7 0.1 5.9e-24 84.7 0.1 2.2 1 1 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2263) Glyco_hydro_28 PF00295.12 KLO15113.1 - 2.3e-59 200.9 9.6 3.1e-59 200.5 6.6 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 BTB PF00651.26 KLO15114.1 - 0.015 15.2 0.0 0.029 14.3 0.0 1.5 1 0 0 1 1 1 0 BTB/POZ domain ArsB PF02040.10 KLO15116.1 - 1.3e-07 30.9 9.6 5.6e-07 28.8 2.8 2.5 2 1 0 2 2 2 2 Arsenical pump membrane protein CitMHS PF03600.11 KLO15116.1 - 3.1e-07 29.3 0.0 0.00038 19.1 0.6 2.6 2 1 0 2 2 2 2 Citrate transporter DUF4342 PF14242.1 KLO15116.1 - 0.0019 17.9 1.2 0.0051 16.5 0.8 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4342) Abhydrolase_3 PF07859.8 KLO15117.1 - 2.3e-24 86.1 0.2 6.2e-24 84.7 0.1 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold DUF2424 PF10340.4 KLO15117.1 - 2.1e-12 46.4 0.0 7.1e-12 44.6 0.0 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF2424) ArsB PF02040.10 KLO15118.1 - 6.6e-21 74.7 21.3 1.3e-16 60.6 6.1 2.7 2 1 1 3 3 3 2 Arsenical pump membrane protein DUF4342 PF14242.1 KLO15118.1 - 0.0099 15.6 0.6 0.0099 15.6 0.4 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF4342) AMP-binding PF00501.23 KLO15119.1 - 4.1e-78 262.6 0.0 5.3e-78 262.2 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 KLO15119.1 - 2e-14 54.2 0.1 4.8e-14 53.0 0.1 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Viral_env_E26 PF11050.3 KLO15120.1 - 0.028 13.6 0.1 0.048 12.8 0.1 1.3 1 0 0 1 1 1 0 Virus envelope protein E26 CCDC-167 PF15188.1 KLO15120.1 - 0.06 13.3 0.1 0.13 12.2 0.1 1.5 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 167 DUF1212 PF06738.7 KLO15121.1 - 1.2e-26 93.4 0.1 1.2e-26 93.4 0.1 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF1212) DUF3815 PF12821.2 KLO15121.1 - 9.2e-10 38.5 22.5 1.2e-09 38.1 4.9 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF3815) BTB PF00651.26 KLO15122.1 - 1.3e-10 41.2 0.0 2.8e-10 40.1 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain BTB PF00651.26 KLO15124.1 - 2.7e-07 30.5 0.0 4.9e-07 29.7 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain DUF3776 PF12618.3 KLO15124.1 - 0.0083 16.6 1.2 0.019 15.5 0.8 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3776) BTB PF00651.26 KLO15126.1 - 2.5e-06 27.4 0.0 0.02 14.8 0.0 2.6 3 0 0 3 3 3 2 BTB/POZ domain HTH_AraC PF00165.18 KLO15126.1 - 0.016 15.0 0.0 0.21 11.4 0.0 2.5 2 0 0 2 2 2 0 Bacterial regulatory helix-turn-helix proteins, AraC family DUF3899 PF13038.1 KLO15126.1 - 0.12 12.5 0.0 0.23 11.6 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3899) polyprenyl_synt PF00348.12 KLO15127.1 - 2.1e-54 184.1 0.0 2.4e-54 183.9 0.0 1.0 1 0 0 1 1 1 1 Polyprenyl synthetase Terpene_synth_C PF03936.11 KLO15127.1 - 0.045 12.9 0.0 0.061 12.5 0.0 1.3 1 0 0 1 1 1 0 Terpene synthase family, metal binding domain BTB PF00651.26 KLO15128.1 - 2.2e-06 27.6 0.0 5e-06 26.4 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain BTB PF00651.26 KLO15129.1 - 1.7e-08 34.4 0.0 3.9e-08 33.2 0.0 1.6 1 0 0 1 1 1 1 BTB/POZ domain PSDC PF12588.3 KLO15130.1 - 2.3e-36 124.4 0.0 4.1e-36 123.6 0.0 1.4 1 0 0 1 1 1 1 Phophatidylserine decarboxylase PS_Dcarbxylase PF02666.10 KLO15130.1 - 2e-32 112.1 0.0 2.5e-32 111.8 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase PSDC PF12588.3 KLO15131.1 - 3e-37 127.3 0.1 1.3e-35 122.0 0.0 2.3 2 0 0 2 2 2 1 Phophatidylserine decarboxylase PS_Dcarbxylase PF02666.10 KLO15131.1 - 6.9e-36 123.4 0.0 8.7e-36 123.1 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase Sugar_tr PF00083.19 KLO15135.1 - 1.5e-103 346.8 15.6 1.7e-103 346.6 10.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KLO15135.1 - 6.5e-26 90.8 26.5 6.5e-26 90.8 18.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 KLO15135.1 - 0.00012 20.4 1.9 0.00012 20.4 1.3 1.8 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) polyprenyl_synt PF00348.12 KLO15136.1 - 5.7e-74 248.2 0.0 6.7e-74 248.0 0.0 1.0 1 0 0 1 1 1 1 Polyprenyl synthetase Phage_Treg PF04761.7 KLO15136.1 - 0.044 13.5 0.0 0.11 12.2 0.0 1.6 1 0 0 1 1 1 0 Lactococcus bacteriophage putative transcription regulator PepSY_2 PF13670.1 KLO15139.1 - 0.34 10.8 1.5 0.6 10.0 1.0 1.4 1 0 0 1 1 1 0 Peptidase propeptide and YPEB domain T4SS PF07996.6 KLO15143.1 - 0.038 13.8 0.1 0.066 13.0 0.1 1.4 1 0 0 1 1 1 0 Type IV secretion system proteins RRM_6 PF14259.1 KLO15144.1 - 1.9e-37 127.0 0.2 1.8e-10 40.6 0.0 4.5 4 0 0 4 4 4 4 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 KLO15144.1 - 3.4e-30 103.4 0.5 5.5e-09 35.5 0.0 4.5 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KLO15144.1 - 5.8e-20 70.8 0.0 0.00045 20.0 0.0 4.6 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF1866 PF08952.6 KLO15144.1 - 2.5e-05 23.8 0.0 0.16 11.5 0.0 3.8 3 1 1 4 4 4 2 Domain of unknown function (DUF1866) RRM_3 PF08777.6 KLO15144.1 - 0.0001 22.0 0.1 0.14 12.0 0.1 2.6 2 0 0 2 2 2 2 RNA binding motif Nup35_RRM_2 PF14605.1 KLO15144.1 - 0.00071 19.2 0.0 0.21 11.4 0.0 3.5 4 0 0 4 4 4 1 Nup53/35/40-type RNA recognition motif ABC_tran PF00005.22 KLO15145.1 - 9.8e-31 106.8 0.0 1.9e-15 57.3 0.0 3.4 2 1 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 KLO15145.1 - 5.6e-12 46.2 0.3 0.0087 16.0 0.1 3.2 3 0 0 3 3 3 3 AAA domain SbcCD_C PF13558.1 KLO15145.1 - 4.1e-06 26.6 0.0 0.017 15.0 0.0 2.8 2 1 0 2 2 2 2 Putative exonuclease SbcCD, C subunit SMC_N PF02463.14 KLO15145.1 - 9.3e-06 25.0 0.0 0.005 16.0 0.0 3.3 3 1 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 KLO15145.1 - 0.001 18.5 0.0 0.0068 15.9 0.0 2.1 2 0 0 2 2 2 1 P-loop containing region of AAA domain NACHT PF05729.7 KLO15145.1 - 0.0031 17.1 0.0 0.21 11.2 0.0 2.7 3 0 0 3 3 3 1 NACHT domain DUF3584 PF12128.3 KLO15145.1 - 0.013 12.9 0.0 0.018 12.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) AAA_22 PF13401.1 KLO15145.1 - 0.018 15.2 0.3 4.1 7.5 0.0 3.4 2 2 0 2 2 2 0 AAA domain AAA_19 PF13245.1 KLO15145.1 - 0.043 13.5 0.1 11 5.8 0.0 2.9 2 0 0 2 2 2 0 Part of AAA domain DUF258 PF03193.11 KLO15145.1 - 0.084 12.0 0.0 1.6 7.9 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function, DUF258 AAA_33 PF13671.1 KLO15145.1 - 0.16 11.8 1.9 12 5.7 0.1 4.0 3 2 0 3 3 3 0 AAA domain AAA_15 PF13175.1 KLO15145.1 - 0.33 9.9 0.0 9.4 5.1 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain DUF3759 PF12585.3 KLO15146.1 - 4.1e-24 84.3 5.0 5.8e-24 83.8 3.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3759) DPRP PF04244.8 KLO15146.1 - 0.13 11.8 0.7 0.18 11.3 0.5 1.1 1 0 0 1 1 1 0 Deoxyribodipyrimidine photo-lyase-related protein Bromodomain PF00439.20 KLO15147.1 - 3.2e-22 78.2 0.5 1.2e-21 76.3 0.3 2.1 2 0 0 2 2 2 1 Bromodomain Bromo_TP PF07524.8 KLO15147.1 - 7.1e-08 32.0 0.0 1.3e-07 31.2 0.0 1.4 1 0 0 1 1 1 1 Bromodomain associated KAR9 PF08580.5 KLO15147.1 - 0.08 11.2 0.4 0.11 10.7 0.3 1.2 1 0 0 1 1 1 0 Yeast cortical protein KAR9 WD40 PF00400.27 KLO15148.1 - 1.7e-36 122.7 9.5 3.1e-07 30.0 0.1 7.3 6 1 1 7 7 7 5 WD domain, G-beta repeat eIF2A PF08662.6 KLO15148.1 - 2.3e-05 24.1 0.3 0.016 14.9 0.1 2.3 2 0 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A Nbas_N PF15492.1 KLO15148.1 - 0.044 12.8 0.1 3.7 6.5 0.0 2.6 2 1 1 3 3 3 0 Neuroblastoma-amplified sequence, N terminal DUF1903 PF08991.5 KLO15149.1 - 1.2e-17 63.7 6.0 1.4e-17 63.5 4.2 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1903) CHCH PF06747.8 KLO15149.1 - 0.0056 16.5 6.7 0.011 15.6 4.6 1.5 1 0 0 1 1 1 1 CHCH domain Cmc1 PF08583.5 KLO15149.1 - 0.1 12.4 9.5 0.1 12.3 0.6 2.1 1 1 1 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like Pet191_N PF10203.4 KLO15149.1 - 0.46 10.5 6.7 0.85 9.7 4.7 1.5 1 0 0 1 1 1 0 Cytochrome c oxidase assembly protein PET191 Cpn60_TCP1 PF00118.19 KLO15150.1 - 3.9e-135 451.2 1.8 4.4e-135 451.0 1.3 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Cerato-platanin PF07249.7 KLO15151.1 - 1.4e-35 121.8 0.3 1.7e-35 121.6 0.2 1.1 1 0 0 1 1 1 1 Cerato-platanin Cerato-platanin PF07249.7 KLO15152.1 - 6.4e-20 71.3 0.1 8.1e-20 71.0 0.1 1.1 1 0 0 1 1 1 1 Cerato-platanin Cerato-platanin PF07249.7 KLO15153.1 - 5e-24 84.5 0.1 6.5e-24 84.2 0.0 1.1 1 0 0 1 1 1 1 Cerato-platanin Cerato-platanin PF07249.7 KLO15154.1 - 5.9e-23 81.1 0.1 7.8e-23 80.7 0.1 1.2 1 0 0 1 1 1 1 Cerato-platanin Hydrophobin PF01185.13 KLO15156.1 - 1.2e-19 70.5 10.9 1.5e-19 70.2 7.5 1.1 1 0 0 1 1 1 1 Fungal hydrophobin Acetyltransf_1 PF00583.19 KLO15161.1 - 4.7e-06 26.5 0.1 7.8e-06 25.8 0.1 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 KLO15161.1 - 0.00061 19.9 0.0 0.0015 18.5 0.0 1.8 1 1 1 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 KLO15161.1 - 0.02 15.0 0.0 0.066 13.3 0.0 2.0 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 KLO15161.1 - 0.081 12.7 0.0 3.6 7.4 0.0 2.2 1 1 0 2 2 2 0 Acetyltransferase (GNAT) domain MOZ_SAS PF01853.13 KLO15161.1 - 0.14 11.4 0.0 0.17 11.1 0.0 1.3 1 0 0 1 1 1 0 MOZ/SAS family But2 PF09792.4 KLO15162.1 - 0.0008 19.1 0.1 0.035 13.8 0.0 2.5 3 0 0 3 3 3 2 Ubiquitin 3 binding protein But2 C-terminal domain DUF3328 PF11807.3 KLO15163.1 - 0.0061 16.2 0.5 0.015 14.9 0.1 1.7 1 1 1 2 2 2 1 Domain of unknown function (DUF3328) DUF3328 PF11807.3 KLO15164.1 - 1.7e-18 67.0 0.0 2.3e-18 66.6 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) DUF3328 PF11807.3 KLO15165.1 - 8.3e-19 68.1 0.5 1e-18 67.8 0.3 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) TRAPPC10 PF12584.3 KLO15165.1 - 0.034 13.6 0.0 0.05 13.1 0.0 1.2 1 0 0 1 1 1 0 Trafficking protein particle complex subunit 10, TRAPPC10 WSC PF01822.14 KLO15166.1 - 1.1e-38 130.9 38.9 1.5e-20 72.8 10.1 2.1 2 0 0 2 2 2 2 WSC domain NAD_binding_6 PF08030.7 KLO15167.1 - 2.8e-16 59.8 0.0 4.3e-16 59.2 0.0 1.3 1 0 0 1 1 1 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.14 KLO15167.1 - 1.9e-14 53.8 11.0 1.9e-14 53.8 7.6 2.5 3 0 0 3 3 3 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.7 KLO15167.1 - 6.4e-13 48.4 0.0 1.3e-12 47.4 0.0 1.5 1 0 0 1 1 1 1 FAD-binding domain DUF2422 PF10337.4 KLO15167.1 - 0.00051 18.9 0.3 0.00083 18.2 0.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2422) NAD_binding_1 PF00175.16 KLO15167.1 - 0.047 14.2 0.1 3.3 8.3 0.0 2.4 1 1 0 2 2 2 0 Oxidoreductase NAD-binding domain EPSP_synthase PF00275.15 KLO15168.1 - 1e-115 386.5 0.0 1.7e-115 385.8 0.0 1.3 1 0 0 1 1 1 1 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) DHQ_synthase PF01761.15 KLO15168.1 - 5.7e-100 333.5 0.2 1e-99 332.7 0.0 1.5 2 0 0 2 2 2 1 3-dehydroquinate synthase DHquinase_I PF01487.10 KLO15168.1 - 8.9e-56 189.0 0.0 1.3e-55 188.4 0.0 1.3 1 0 0 1 1 1 1 Type I 3-dehydroquinase SKI PF01202.17 KLO15168.1 - 1.7e-34 118.9 0.0 2.1e-33 115.4 0.0 2.4 2 0 0 2 2 2 1 Shikimate kinase Shikimate_dh_N PF08501.6 KLO15168.1 - 2.1e-24 85.3 0.0 7.1e-24 83.6 0.0 2.0 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain Shikimate_DH PF01488.15 KLO15168.1 - 3e-11 43.5 0.0 7.9e-11 42.1 0.0 1.7 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Fe-ADH_2 PF13685.1 KLO15168.1 - 1.8e-09 37.2 0.0 5.5e-09 35.6 0.0 1.8 2 0 0 2 2 2 1 Iron-containing alcohol dehydrogenase AAA_17 PF13207.1 KLO15168.1 - 1.5e-05 25.7 0.0 5.3e-05 24.0 0.0 1.9 1 0 0 1 1 1 1 AAA domain RTC PF01137.16 KLO15168.1 - 0.027 13.2 0.0 0.056 12.2 0.0 1.5 1 0 0 1 1 1 0 RNA 3'-terminal phosphate cyclase LRR_6 PF13516.1 KLO15169.1 - 2.6e-10 39.2 13.7 1.2 9.4 0.0 8.3 9 0 0 9 9 9 4 Leucine Rich repeat LRR_4 PF12799.2 KLO15169.1 - 4e-05 23.1 22.4 0.26 10.9 0.0 7.4 5 2 2 8 8 8 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 KLO15169.1 - 8e-05 22.1 14.6 15 6.0 0.0 8.7 9 1 1 10 10 10 2 Leucine Rich Repeat LRR_8 PF13855.1 KLO15169.1 - 0.72 9.6 22.1 0.81 9.4 0.3 6.1 3 2 5 8 8 8 0 Leucine rich repeat Abhydrolase_6 PF12697.2 KLO15170.1 - 2.2e-18 66.9 0.1 3.3e-18 66.3 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KLO15170.1 - 4.2e-09 36.3 0.1 9.3e-09 35.1 0.1 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KLO15170.1 - 1.2e-05 24.9 0.0 4.5e-05 23.1 0.0 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold DUF2305 PF10230.4 KLO15170.1 - 0.041 13.2 0.0 0.065 12.6 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2305) Bestrophin PF01062.16 KLO15171.1 - 3.2e-43 147.7 2.0 2.2e-25 89.2 0.0 2.1 2 0 0 2 2 2 2 Bestrophin, RFP-TM, chloride channel Bestrophin PF01062.16 KLO15172.1 - 4.1e-48 163.8 1.0 2.3e-29 102.2 0.1 2.1 2 0 0 2 2 2 2 Bestrophin, RFP-TM, chloride channel DUF3821 PF12863.2 KLO15172.1 - 0.14 11.8 0.0 0.24 11.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3821) O-ag_pol_Wzy PF14296.1 KLO15172.1 - 0.28 9.7 6.6 2.4 6.6 0.9 2.1 2 0 0 2 2 2 0 O-antigen polysaccharide polymerase Wzy Pyr_redox_2 PF07992.9 KLO15173.1 - 3.5e-25 89.0 0.0 6.4e-25 88.2 0.0 1.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 KLO15173.1 - 5e-12 46.0 0.4 5.9e-11 42.6 0.1 2.8 2 2 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 KLO15173.1 - 2.7e-05 24.3 0.9 0.0046 17.0 0.0 3.0 4 1 0 4 4 4 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 KLO15173.1 - 0.008 14.6 3.1 0.022 13.2 0.0 2.7 1 1 2 3 3 3 1 HI0933-like protein CUE PF02845.11 KLO15174.1 - 1.4e-11 43.6 0.0 2.4e-11 42.9 0.0 1.4 1 0 0 1 1 1 1 CUE domain AA_permease PF00324.16 KLO15175.1 - 4.8e-97 325.2 36.5 3.3e-96 322.5 25.3 1.8 1 1 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 KLO15175.1 - 3e-27 95.2 31.9 4.7e-27 94.5 22.0 1.3 1 1 0 1 1 1 1 Amino acid permease Abhydrolase_6 PF12697.2 KLO15178.1 - 2.1e-19 70.3 0.1 3.1e-19 69.7 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KLO15178.1 - 1.7e-08 34.3 0.0 3.4e-08 33.3 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KLO15178.1 - 3e-08 33.5 0.0 5.3e-08 32.7 0.0 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_8 PF06259.7 KLO15178.1 - 0.093 12.2 0.0 0.2 11.1 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase YoaP PF14268.1 KLO15184.1 - 0.12 11.6 0.0 0.21 10.8 0.0 1.3 1 0 0 1 1 1 0 YoaP-like peroxidase PF00141.18 KLO15186.1 - 9.3e-22 77.6 0.0 4.1e-21 75.5 0.0 1.8 1 1 0 1 1 1 1 Peroxidase DUF3415 PF11895.3 KLO15186.1 - 5.1e-19 67.9 1.1 5.1e-19 67.9 0.8 2.2 3 0 0 3 3 3 1 Domain of unknown function (DUF3415) Cloacin_immun PF03513.9 KLO15186.1 - 0.03 14.3 0.0 0.061 13.3 0.0 1.5 1 0 0 1 1 1 0 Cloacin immunity protein L51_S25_CI-B8 PF05047.11 KLO15187.1 - 1.7e-14 53.2 0.0 2.2e-14 52.9 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain RGS PF00615.14 KLO15188.1 - 3.3e-11 43.3 3.7 1.1e-05 25.4 0.3 3.0 2 1 0 2 2 2 2 Regulator of G protein signaling domain Pex19 PF04614.7 KLO15189.1 - 2e-56 191.3 4.9 2.8e-56 190.9 2.9 1.5 1 1 0 1 1 1 1 Pex19 protein family CAP_N PF01213.14 KLO15189.1 - 0.13 11.5 1.4 0.33 10.2 1.0 1.6 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Ndc1_Nup PF09531.5 KLO15190.1 - 8.9e-54 182.9 4.7 1e-53 182.7 3.3 1.0 1 0 0 1 1 1 1 Nucleoporin protein Ndc1-Nup RF-1 PF00472.15 KLO15191.1 - 4e-36 123.2 3.8 8.6e-36 122.2 2.6 1.5 1 0 0 1 1 1 1 RF-1 domain PCRF PF03462.13 KLO15191.1 - 3.9e-30 103.9 0.2 1.7e-29 101.8 0.0 2.1 3 0 0 3 3 3 1 PCRF domain DUF221 PF02714.10 KLO15192.1 - 1.8e-103 345.8 20.3 2.7e-103 345.2 14.1 1.3 1 0 0 1 1 1 1 Domain of unknown function DUF221 RSN1_TM PF13967.1 KLO15192.1 - 2.3e-37 127.9 0.7 2.3e-37 127.9 0.5 2.3 2 0 0 2 2 2 1 Late exocytosis, associated with Golgi transport DUF4463 PF14703.1 KLO15192.1 - 1.1e-09 38.6 0.0 2.4e-09 37.5 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4463) WD40 PF00400.27 KLO15193.1 - 8.4e-08 31.8 17.1 5.7e-07 29.1 0.3 5.4 5 0 0 5 5 5 2 WD domain, G-beta repeat CMAS PF02353.15 KLO15194.1 - 3.5e-67 226.3 0.2 4.2e-67 226.0 0.1 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_23 PF13489.1 KLO15194.1 - 4.3e-11 42.8 0.0 1.8e-10 40.7 0.0 1.9 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 KLO15194.1 - 2.3e-09 37.6 0.0 8.2e-09 35.8 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 KLO15194.1 - 3e-06 27.8 0.0 9.3e-06 26.2 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 KLO15194.1 - 8.3e-06 26.2 0.0 1.5e-05 25.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KLO15194.1 - 8.9e-06 25.7 0.0 4.1e-05 23.5 0.0 2.1 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 KLO15194.1 - 9.4e-06 25.9 0.0 2e-05 24.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KLO15194.1 - 1.3e-05 24.8 0.0 2.7e-05 23.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KLO15194.1 - 0.0001 21.7 0.0 0.00017 21.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain PCMT PF01135.14 KLO15194.1 - 0.00039 20.0 0.0 0.0016 18.0 0.0 1.8 1 1 1 2 2 2 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) DOT1 PF08123.8 KLO15194.1 - 0.002 17.4 0.0 0.0039 16.5 0.0 1.4 1 0 0 1 1 1 1 Histone methylation protein DOT1 PrmA PF06325.8 KLO15194.1 - 0.019 14.0 0.0 0.03 13.4 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) MetW PF07021.7 KLO15194.1 - 0.058 12.7 0.0 0.11 11.8 0.0 1.4 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Methyltransf_32 PF13679.1 KLO15194.1 - 0.085 12.5 0.0 0.16 11.6 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Pkinase_Tyr PF07714.12 KLO15195.1 - 4.9e-33 114.2 0.0 5.5e-33 114.1 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 KLO15195.1 - 4.8e-29 101.2 0.0 5.4e-29 101.1 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.18 KLO15195.1 - 0.049 13.3 0.2 0.049 13.3 0.1 2.1 2 1 0 3 3 3 0 Phosphotransferase enzyme family EcKinase PF02958.15 KLO15195.1 - 0.052 12.6 0.0 0.074 12.1 0.0 1.2 1 0 0 1 1 1 0 Ecdysteroid kinase Solute_trans_a PF03619.11 KLO15196.1 - 4e-57 193.6 5.1 1.4e-46 159.0 1.4 2.9 1 1 1 2 2 2 2 Organic solute transporter Ostalpha UQ_con PF00179.21 KLO15196.1 - 3.1e-38 130.3 0.0 5.7e-38 129.5 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Nrap PF03813.9 KLO15197.1 - 9.8e-222 738.3 0.0 1.2e-221 738.1 0.0 1.0 1 0 0 1 1 1 1 Nrap protein LysM PF01476.15 KLO15198.1 - 3.7e-13 49.1 0.0 8.8e-06 25.5 0.0 2.3 2 0 0 2 2 2 2 LysM domain Binary_toxB PF03495.9 KLO15200.1 - 2.3 6.7 7.2 3.3 6.2 5.0 1.2 1 0 0 1 1 1 0 Clostridial binary toxin B/anthrax toxin PA adh_short PF00106.20 KLO15201.1 - 2e-22 79.8 2.4 1.4e-15 57.6 0.3 2.2 1 1 1 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.1 KLO15201.1 - 9.5e-20 71.3 0.1 8.8e-12 45.2 0.0 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KLO15201.1 - 5.3e-09 35.9 1.7 7.3e-09 35.5 0.1 1.8 2 0 0 2 2 2 1 KR domain Epimerase PF01370.16 KLO15201.1 - 0.026 13.9 0.1 0.044 13.2 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 KLO15201.1 - 0.028 14.4 0.1 0.063 13.2 0.1 1.7 1 0 0 1 1 1 0 NADH(P)-binding adh_short PF00106.20 KLO15202.1 - 1.4e-21 77.1 2.8 1.3e-14 54.4 0.2 2.1 1 1 1 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.1 KLO15202.1 - 1.7e-19 70.5 0.0 3.6e-11 43.2 0.0 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KLO15202.1 - 3.7e-08 33.2 0.8 1.3e-07 31.4 0.0 1.9 2 0 0 2 2 2 1 KR domain NAD_binding_10 PF13460.1 KLO15202.1 - 0.014 15.4 0.2 0.038 14.0 0.1 1.7 1 1 0 1 1 1 0 NADH(P)-binding Epimerase PF01370.16 KLO15202.1 - 0.064 12.6 0.1 0.18 11.2 0.0 1.7 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family Oxidored_FMN PF00724.15 KLO15203.1 - 5.6e-94 314.9 0.0 7.4e-94 314.5 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family EHN PF06441.7 KLO15204.1 - 2.7e-23 82.0 0.0 4e-23 81.4 0.0 1.3 1 0 0 1 1 1 1 Epoxide hydrolase N terminus Abhydrolase_6 PF12697.2 KLO15204.1 - 7.5e-08 32.5 0.1 4.5e-05 23.4 0.0 2.3 2 0 0 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KLO15204.1 - 0.027 14.0 0.0 0.041 13.4 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold EHN PF06441.7 KLO15205.1 - 5.7e-19 68.0 0.0 9.7e-19 67.3 0.0 1.3 1 0 0 1 1 1 1 Epoxide hydrolase N terminus Abhydrolase_6 PF12697.2 KLO15205.1 - 1.5e-07 31.5 0.9 1.4e-05 25.0 0.2 2.5 2 1 0 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KLO15205.1 - 0.013 15.0 0.1 0.025 14.1 0.1 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold Pkinase_Tyr PF07714.12 KLO15208.1 - 1.8e-35 122.2 0.0 2.7e-35 121.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 KLO15208.1 - 2.4e-34 118.6 0.0 3.5e-34 118.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.18 KLO15208.1 - 0.0059 16.3 0.1 0.02 14.6 0.1 2.0 1 1 0 1 1 1 1 Phosphotransferase enzyme family HMG14_17 PF01101.13 KLO15209.1 - 3.4 8.4 11.0 0.81 10.4 0.4 2.9 2 1 1 3 3 3 0 HMG14 and HMG17 zf-PARP PF00645.13 KLO15210.1 - 2.8e-25 88.3 0.2 3.9e-25 87.9 0.1 1.2 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region Tannase PF07519.6 KLO15211.1 - 2.1e-108 363.0 0.0 2.8e-108 362.6 0.0 1.1 1 0 0 1 1 1 1 Tannase and feruloyl esterase Abhydrolase_5 PF12695.2 KLO15211.1 - 1.4e-05 24.8 0.0 0.035 13.8 0.0 2.3 2 0 0 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KLO15211.1 - 0.00086 19.2 0.0 0.0047 16.8 0.0 2.1 2 1 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KLO15211.1 - 0.0033 17.0 0.0 0.18 11.3 0.0 2.6 3 0 0 3 3 3 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 KLO15211.1 - 0.046 12.9 0.0 0.61 9.2 0.1 2.0 2 0 0 2 2 2 0 Prolyl oligopeptidase family Tannase PF07519.6 KLO15212.1 - 4.8e-108 361.9 0.0 5.8e-108 361.6 0.0 1.1 1 0 0 1 1 1 1 Tannase and feruloyl esterase Abhydrolase_5 PF12695.2 KLO15212.1 - 1.7e-05 24.5 0.0 0.11 12.2 0.0 2.4 2 0 0 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KLO15212.1 - 0.00055 19.8 0.0 0.015 15.1 0.0 2.6 1 1 1 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KLO15212.1 - 0.0014 18.2 0.0 0.0037 16.8 0.0 1.7 2 0 0 2 2 2 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 KLO15212.1 - 0.097 11.8 0.2 1.2 8.3 0.2 2.1 2 0 0 2 2 2 0 Prolyl oligopeptidase family Esterase PF00756.15 KLO15212.1 - 0.14 11.5 0.0 0.98 8.7 0.0 2.1 2 0 0 2 2 2 0 Putative esterase YrhK PF14145.1 KLO15213.1 - 0.028 14.0 11.0 0.94 9.1 0.2 3.7 3 2 0 3 3 3 0 YrhK-like protein QCR10 PF09796.4 KLO15213.1 - 0.06 13.0 2.9 4 7.1 0.1 2.7 2 0 0 2 2 2 0 Ubiquinol-cytochrome-c reductase complex subunit (QCR10) DUF4386 PF14329.1 KLO15213.1 - 3.8 6.9 11.8 0.14 11.5 2.2 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4386) Hemerythrin PF01814.18 KLO15214.1 - 5e-12 46.1 5.2 9.4e-12 45.2 3.6 1.4 1 1 0 1 1 1 1 Hemerythrin HHE cation binding domain Pkinase_Tyr PF07714.12 KLO15215.1 - 1.5e-33 116.0 0.0 3.5e-33 114.7 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 KLO15215.1 - 1.1e-32 113.2 0.0 1.7e-32 112.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase PF00069.20 KLO15216.1 - 5.2e-38 130.6 0.0 8.8e-38 129.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KLO15216.1 - 9.7e-38 129.7 0.0 2.1e-37 128.5 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Zn_clus PF00172.13 KLO15216.1 - 3.2e-06 26.9 8.9 6.1e-06 26.0 6.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-UBR PF02207.15 KLO15217.1 - 1.7e-10 40.4 12.2 1.7e-10 40.4 8.5 3.9 3 1 1 5 5 5 1 Putative zinc finger in N-recognin (UBR box) PHD PF00628.24 KLO15217.1 - 3.8e-07 29.6 0.6 3.8e-07 29.6 0.4 4.0 5 0 0 5 5 5 1 PHD-finger Methyltransf_16 PF10294.4 KLO15218.1 - 1.4e-44 151.6 0.0 1.8e-44 151.2 0.0 1.1 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_18 PF12847.2 KLO15218.1 - 3e-05 24.5 0.0 4.6e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KLO15218.1 - 0.0019 17.5 0.0 0.0031 16.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_26 PF13659.1 KLO15218.1 - 0.0051 16.8 0.1 0.015 15.3 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain PrmA PF06325.8 KLO15218.1 - 0.026 13.6 0.0 0.038 13.1 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_31 PF13847.1 KLO15218.1 - 0.079 12.5 0.0 0.12 11.9 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain p450 PF00067.17 KLO15219.1 - 3.5e-67 226.9 0.0 1.9e-66 224.4 0.0 2.0 1 1 0 1 1 1 1 Cytochrome P450 SSF PF00474.12 KLO15220.1 - 4.3e-21 75.0 29.8 4.3e-21 75.0 20.6 1.6 2 0 0 2 2 2 1 Sodium:solute symporter family WTF PF03303.8 KLO15220.1 - 0.11 11.9 0.2 0.33 10.3 0.2 1.8 1 0 0 1 1 1 0 WTF protein YjeF_N PF03853.10 KLO15221.1 - 1.2e-37 129.1 0.0 1.4e-37 128.8 0.0 1.1 1 0 0 1 1 1 1 YjeF-related protein N-terminus HTH_34 PF13601.1 KLO15221.1 - 0.064 13.3 0.0 0.15 12.1 0.0 1.6 1 0 0 1 1 1 0 Winged helix DNA-binding domain adh_short PF00106.20 KLO15222.1 - 1.3e-26 93.4 1.8 2.1e-26 92.8 1.3 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KLO15222.1 - 4.4e-21 75.7 0.6 5.3e-21 75.5 0.4 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KLO15222.1 - 1e-07 31.7 1.4 1.8e-07 30.9 0.9 1.4 1 0 0 1 1 1 1 KR domain Tannase PF07519.6 KLO15223.1 - 5e-103 345.3 0.0 8.5e-103 344.5 0.0 1.3 1 1 0 1 1 1 1 Tannase and feruloyl esterase Abhydrolase_6 PF12697.2 KLO15223.1 - 7.9e-05 22.6 0.0 0.00023 21.0 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KLO15223.1 - 0.00019 21.2 0.0 0.35 10.6 0.0 2.2 2 0 0 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KLO15223.1 - 0.0049 16.4 0.0 0.0078 15.7 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Profilin PF00235.14 KLO15224.1 - 2.2e-37 127.8 0.2 2.4e-37 127.7 0.1 1.0 1 0 0 1 1 1 1 Profilin AAA PF00004.24 KLO15225.1 - 2.6e-21 76.1 0.0 4.5e-21 75.4 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 KLO15225.1 - 0.0021 17.8 0.1 0.011 15.5 0.0 2.3 1 1 2 3 3 3 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 KLO15225.1 - 0.0042 17.2 0.1 0.13 12.4 0.0 2.4 1 1 1 2 2 2 1 AAA domain NTPase_1 PF03266.10 KLO15225.1 - 0.0056 16.4 0.0 0.009 15.7 0.0 1.3 1 0 0 1 1 1 1 NTPase Guanylate_kin PF00625.16 KLO15225.1 - 0.062 12.7 0.0 0.11 11.9 0.0 1.5 1 0 0 1 1 1 0 Guanylate kinase AAA_16 PF13191.1 KLO15225.1 - 0.069 13.1 0.1 0.45 10.4 0.0 2.0 1 1 1 2 2 2 0 AAA ATPase domain AAA_19 PF13245.1 KLO15225.1 - 0.11 12.3 0.0 0.21 11.3 0.0 1.5 1 0 0 1 1 1 0 Part of AAA domain DUF815 PF05673.8 KLO15225.1 - 0.11 11.3 0.0 0.14 11.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Macro PF01661.16 KLO15226.1 - 6.8e-42 142.1 0.2 1.1e-41 141.4 0.1 1.3 1 0 0 1 1 1 1 Macro domain PS_Dcarbxylase PF02666.10 KLO15227.1 - 2.1e-56 190.4 0.0 3.3e-56 189.8 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase C2 PF00168.25 KLO15227.1 - 3.5e-36 122.9 0.2 4.8e-18 64.7 0.0 2.7 2 0 0 2 2 2 2 C2 domain EF-hand_7 PF13499.1 KLO15227.1 - 3.3e-06 27.1 0.2 8.1e-06 25.8 0.1 1.7 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.1 KLO15227.1 - 0.0045 16.7 0.1 0.16 11.9 0.0 2.8 2 0 0 2 2 2 1 EF-hand domain EF-hand_1 PF00036.27 KLO15227.1 - 0.085 12.2 0.0 0.61 9.5 0.0 2.5 2 0 0 2 2 2 0 EF hand CEP76-C2 PF15627.1 KLO15227.1 - 0.15 11.5 0.0 1.1 8.7 0.0 2.1 2 0 0 2 2 2 0 CEP76 C2 domain TRP PF06011.7 KLO15228.1 - 0.014 14.0 10.6 0.064 11.8 1.6 2.2 1 1 0 2 2 2 0 Transient receptor potential (TRP) ion channel gpUL132 PF11359.3 KLO15228.1 - 0.2 10.9 3.1 0.17 11.1 0.2 1.9 2 0 0 2 2 2 0 Glycoprotein UL132 DUF1980 PF09323.5 KLO15228.1 - 0.62 9.7 3.4 14 5.4 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1980) PARP PF00644.15 KLO15229.1 - 1.8e-15 56.9 5.9 1.8e-11 43.8 4.1 3.4 1 1 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain PARP PF00644.15 KLO15230.1 - 0.0089 15.4 0.9 0.89 8.9 0.1 2.2 2 0 0 2 2 2 2 Poly(ADP-ribose) polymerase catalytic domain L71 PF02448.10 KLO15230.1 - 0.46 10.3 6.1 4.5 7.1 1.7 2.7 2 0 0 2 2 2 0 L71 family PARP PF00644.15 KLO15231.1 - 2.5e-19 69.5 3.0 6.8e-11 41.9 0.6 3.0 2 1 0 2 2 2 2 Poly(ADP-ribose) polymerase catalytic domain Lact_bio_phlase PF09508.5 KLO15231.1 - 0.16 9.5 0.0 0.23 9.0 0.0 1.1 1 0 0 1 1 1 0 Lacto-N-biose phosphorylase zf-CCCH PF00642.19 KLO15233.1 - 1.2e-05 24.8 1.3 1.2e-05 24.8 0.9 2.1 3 0 0 3 3 3 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) DUF2058 PF09831.4 KLO15233.1 - 7.9 6.3 16.1 0.19 11.6 4.8 2.5 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2058) RRM_5 PF13893.1 KLO15234.1 - 9.8e-07 28.5 0.0 2.5e-06 27.2 0.0 1.7 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 KLO15234.1 - 1.1e-05 24.9 0.0 1.9e-05 24.2 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 KLO15234.1 - 2.5e-05 23.9 0.0 5.2e-05 22.9 0.0 1.5 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif RRM_6 PF14259.1 KLO15234.1 - 0.00026 20.9 0.0 0.0005 19.9 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Hexapep_2 PF14602.1 KLO15235.1 - 0.043 13.3 0.0 2.6 7.6 0.0 2.5 2 0 0 2 2 2 0 Hexapeptide repeat of succinyl-transferase DUF2693 PF10902.3 KLO15235.1 - 0.11 12.4 0.0 0.22 11.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2693) Mito_carr PF00153.22 KLO15237.1 - 5.2e-57 189.5 0.7 3e-19 68.4 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Topo_Zn_Ribbon PF08272.6 KLO15237.1 - 0.15 11.4 0.4 0.88 8.9 0.0 2.4 3 0 0 3 3 3 0 Topoisomerase I zinc-ribbon-like zf-TRAF PF02176.13 KLO15238.1 - 0.15 12.4 2.6 0.27 11.6 1.8 1.4 1 0 0 1 1 1 0 TRAF-type zinc finger zf-C2H2_jaz PF12171.3 KLO15238.1 - 2.7 8.2 6.3 2.8 8.1 1.1 2.4 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding Coq4 PF05019.8 KLO15239.1 - 1.9e-96 321.3 0.0 2.2e-96 321.0 0.0 1.1 1 0 0 1 1 1 1 Coenzyme Q (ubiquinone) biosynthesis protein Coq4 Med7 PF05983.6 KLO15241.1 - 0.006 16.3 0.1 0.01 15.6 0.0 1.3 1 0 0 1 1 1 1 MED7 protein Rubrerythrin PF02915.12 KLO15242.1 - 0.00023 21.4 4.6 0.00023 21.4 3.2 1.6 2 0 0 2 2 2 1 Rubrerythrin BolA PF01722.13 KLO15243.1 - 1.1e-15 57.3 0.1 1.4e-15 57.0 0.0 1.1 1 0 0 1 1 1 1 BolA-like protein DUF1882 PF08966.6 KLO15243.1 - 0.03 14.3 0.9 0.042 13.8 0.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1882) GMP_synt_C PF00958.17 KLO15244.1 - 1.5e-41 140.0 0.1 2.9e-41 139.0 0.1 1.5 1 0 0 1 1 1 1 GMP synthase C terminal domain GATase PF00117.23 KLO15244.1 - 1e-36 126.2 0.0 1.8e-36 125.3 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.8 KLO15244.1 - 9e-11 41.6 0.0 1.8e-10 40.6 0.0 1.5 1 0 0 1 1 1 1 Peptidase C26 NAD_synthase PF02540.12 KLO15244.1 - 2.1e-10 39.9 0.1 5.3e-05 22.2 0.0 2.3 2 0 0 2 2 2 2 NAD synthase tRNA_Me_trans PF03054.11 KLO15244.1 - 0.0045 15.5 0.1 0.0081 14.7 0.0 1.4 1 0 0 1 1 1 1 tRNA methyl transferase QueC PF06508.8 KLO15244.1 - 0.011 15.0 0.3 0.16 11.2 0.0 2.4 3 0 0 3 3 3 0 Queuosine biosynthesis protein QueC DUF2392 PF10288.4 KLO15244.1 - 0.011 16.0 0.0 0.021 15.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2392) ThiI PF02568.9 KLO15244.1 - 0.016 14.6 0.0 0.028 13.8 0.0 1.4 1 0 0 1 1 1 0 Thiamine biosynthesis protein (ThiI) Asn_synthase PF00733.16 KLO15244.1 - 0.017 14.6 0.0 0.029 13.8 0.0 1.3 1 0 0 1 1 1 0 Asparagine synthase tRNA-synt_1g PF09334.6 KLO15245.1 - 3e-127 424.5 0.0 3.8e-127 424.1 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (M) WHEP-TRS PF00458.15 KLO15245.1 - 2e-07 30.5 7.3 2e-07 30.5 5.1 2.0 2 0 0 2 2 2 1 WHEP-TRS domain tRNA-synt_1 PF00133.17 KLO15245.1 - 4.9e-05 21.5 0.0 0.00021 19.4 0.0 2.0 2 1 1 3 3 3 1 tRNA synthetases class I (I, L, M and V) Mu-like_Com PF10122.4 KLO15245.1 - 0.091 11.8 2.6 0.91 8.6 0.5 2.6 2 0 0 2 2 2 0 Mu-like prophage protein Com HypA PF01155.14 KLO15245.1 - 0.17 11.5 1.3 0.38 10.4 0.8 1.7 1 1 0 1 1 1 0 Hydrogenase expression/synthesis hypA family DZR PF12773.2 KLO15245.1 - 0.5 10.2 7.6 2.1 8.2 5.3 2.0 1 1 0 1 1 1 0 Double zinc ribbon C1_1 PF00130.17 KLO15245.1 - 2.7 7.7 4.7 6.3 6.6 2.6 2.0 1 1 1 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) DUF1183 PF06682.7 KLO15246.1 - 6.5e-56 190.2 6.1 3.4e-55 187.8 4.2 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF1183) Gly-zipper_OmpA PF13436.1 KLO15246.1 - 0.034 13.8 0.4 0.06 13.0 0.3 1.3 1 0 0 1 1 1 0 Glycine-zipper containing OmpA-like membrane domain DUF3042 PF11240.3 KLO15246.1 - 0.088 12.6 0.0 0.13 12.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3042) Chordopox_A13L PF05961.6 KLO15246.1 - 0.13 12.1 0.0 0.22 11.5 0.0 1.3 1 0 0 1 1 1 0 Chordopoxvirus A13L protein DUF2615 PF11027.3 KLO15246.1 - 0.16 11.9 0.0 0.4 10.6 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2615) OPT PF03169.10 KLO15247.1 - 7.7e-149 496.9 15.0 8.8e-149 496.7 10.4 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein DUF3995 PF13160.1 KLO15247.1 - 0.1 12.6 0.0 0.1 12.6 0.0 4.2 4 1 1 5 5 5 0 Protein of unknown function (DUF3995) Zn_clus PF00172.13 KLO15248.1 - 2.3e-08 33.8 5.5 3e-08 33.4 3.8 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Adeno_E1A PF02703.9 KLO15248.1 - 0.15 11.4 1.0 0.16 11.3 0.7 1.0 1 0 0 1 1 1 0 Early E1A protein Dickkopf_N PF04706.7 KLO15248.1 - 0.22 11.7 6.8 0.14 12.3 2.6 1.8 1 1 1 2 2 2 0 Dickkopf N-terminal cysteine-rich region CDC73 PF05179.9 KLO15250.1 - 1.9e-56 191.4 0.3 2.5e-56 191.0 0.2 1.1 1 0 0 1 1 1 1 RNA pol II accessory factor, Cdc73 family MFS_1 PF07690.11 KLO15251.1 - 1.3e-20 73.4 33.5 1.8e-17 63.0 15.9 3.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Amidohydro_2 PF04909.9 KLO15252.1 - 1.4e-32 113.3 0.1 2e-32 112.8 0.1 1.2 1 0 0 1 1 1 1 Amidohydrolase TatD_DNase PF01026.16 KLO15252.1 - 0.0096 15.1 0.1 0.032 13.4 0.0 1.9 2 0 0 2 2 2 1 TatD related DNase YchF-GTPase_C PF06071.8 KLO15253.1 - 8.6e-36 121.5 0.0 1.8e-35 120.5 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF933) MMR_HSR1 PF01926.18 KLO15253.1 - 2.8e-14 53.0 0.0 9.2e-14 51.3 0.0 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 KLO15253.1 - 5.8e-06 25.6 0.0 3.3e-05 23.1 0.0 2.0 2 0 0 2 2 2 1 Ferrous iron transport protein B ArgK PF03308.11 KLO15253.1 - 0.022 13.5 0.3 0.065 11.9 0.0 1.8 2 0 0 2 2 2 0 ArgK protein AAA_17 PF13207.1 KLO15253.1 - 0.04 14.7 0.5 0.16 12.7 0.0 2.2 2 1 1 3 3 3 0 AAA domain AAA_18 PF13238.1 KLO15253.1 - 0.065 13.5 0.2 1.3 9.3 0.0 2.4 2 1 0 2 2 2 0 AAA domain DUF2829 PF11195.3 KLO15253.1 - 0.16 12.4 2.3 1.3 9.5 0.3 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2829) F-box-like PF12937.2 KLO15256.1 - 2.6e-06 27.0 0.2 5.4e-06 26.0 0.1 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KLO15256.1 - 0.035 13.7 0.6 0.035 13.7 0.4 2.4 2 0 0 2 2 2 0 F-box domain IBR PF01485.16 KLO15258.1 - 3.5e-12 45.9 29.2 3.2e-07 30.1 4.6 3.6 3 0 0 3 3 3 3 IBR domain Sugar_tr PF00083.19 KLO15259.1 - 2.8e-117 392.0 27.2 3.5e-117 391.7 18.8 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KLO15259.1 - 6.9e-27 94.0 58.5 4.6e-20 71.6 14.5 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 KLO15259.1 - 8.3e-05 21.1 35.2 0.006 15.0 1.2 3.7 3 1 1 4 4 4 3 MFS/sugar transport protein p450 PF00067.17 KLO15260.1 - 1.4e-69 234.7 0.0 1.8e-69 234.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Ank_2 PF12796.2 KLO15261.1 - 6.9e-11 42.3 0.0 4e-08 33.4 0.0 2.3 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 KLO15261.1 - 5.3e-06 25.9 0.0 0.046 13.5 0.0 3.1 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.1 KLO15261.1 - 0.0042 17.5 0.2 1.2 9.7 0.1 3.2 2 1 2 4 4 4 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 KLO15261.1 - 0.0062 16.6 0.0 7.2 7.1 0.0 3.8 4 0 0 4 4 4 1 Ankyrin repeat Ank_5 PF13857.1 KLO15261.1 - 0.0085 16.3 0.0 11 6.4 0.0 3.2 2 1 1 3 3 3 2 Ankyrin repeats (many copies) zf-MYND PF01753.13 KLO15262.1 - 3e-11 42.9 7.6 7.9e-11 41.6 5.2 1.8 1 0 0 1 1 1 1 MYND finger Peptidase_C14 PF00656.17 KLO15264.1 - 2.5e-70 236.9 0.1 3.2e-70 236.6 0.1 1.1 1 0 0 1 1 1 1 Caspase domain Raptor_N PF14538.1 KLO15264.1 - 0.0057 16.4 0.7 0.049 13.4 0.0 2.5 3 0 0 3 3 3 1 Raptor N-terminal CASPase like domain Metallophos_2 PF12850.2 KLO15265.1 - 1.5e-08 34.5 0.0 2.4e-08 33.9 0.0 1.4 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.23 KLO15265.1 - 4.4e-08 32.7 0.1 5.8e-08 32.3 0.0 1.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_3 PF14582.1 KLO15265.1 - 0.017 14.2 0.0 0.06 12.4 0.0 1.7 2 0 0 2 2 2 0 Metallophosphoesterase, calcineurin superfamily eIF-1a PF01176.14 KLO15266.1 - 6.2e-24 83.1 0.6 9.7e-24 82.5 0.4 1.3 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 Cellulase PF00150.13 KLO15267.1 - 2.6e-42 144.9 0.0 3.2e-42 144.6 0.0 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) AP_endonuc_2 PF01261.19 KLO15267.1 - 0.11 11.7 0.0 0.48 9.6 0.0 2.1 1 1 1 2 2 2 0 Xylose isomerase-like TIM barrel Sugar_tr PF00083.19 KLO15269.1 - 2.4e-104 349.4 23.9 2.7e-104 349.2 16.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KLO15269.1 - 2.4e-33 115.3 51.9 1.3e-28 99.7 17.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Histone PF00125.19 KLO15271.1 - 7.4e-23 80.4 0.2 1e-22 79.9 0.1 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 KLO15271.1 - 0.003 17.5 0.0 0.0056 16.7 0.0 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone LRR_8 PF13855.1 KLO15274.1 - 5.5e-05 22.8 6.8 0.032 13.9 0.4 4.5 4 1 0 4 4 4 2 Leucine rich repeat F-box-like PF12937.2 KLO15274.1 - 6.2e-05 22.6 0.1 0.00016 21.3 0.0 1.8 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.2 KLO15274.1 - 0.0055 16.2 4.6 0.38 10.4 0.0 4.9 4 1 0 4 4 4 1 Leucine Rich repeats (2 copies) F-box PF00646.28 KLO15274.1 - 0.019 14.6 0.2 0.078 12.6 0.2 2.2 1 0 0 1 1 1 0 F-box domain SH3_9 PF14604.1 KLO15275.1 - 0.02 14.4 0.0 0.066 12.8 0.0 2.0 2 1 0 2 2 2 0 Variant SH3 domain SKG6 PF08693.5 KLO15275.1 - 0.029 13.6 1.9 0.088 12.1 1.3 1.9 1 1 0 1 1 1 0 Transmembrane alpha-helix domain DdrB PF12747.2 KLO15277.1 - 0.14 11.8 0.0 0.33 10.6 0.0 1.6 2 0 0 2 2 2 0 DdrB-like protein Trp_oprn_chp PF09534.5 KLO15278.1 - 0.007 16.0 0.5 0.015 14.9 0.4 1.5 1 0 0 1 1 1 1 Tryptophan-associated transmembrane protein (Trp_oprn_chp) Kei1 PF08552.6 KLO15278.1 - 0.96 9.0 3.3 0.27 10.8 0.1 1.6 2 0 0 2 2 2 0 Inositolphosphorylceramide synthase subunit Kei1 TFIIF_beta PF02270.10 KLO15281.1 - 8.8e-52 176.5 0.2 8.9e-49 166.7 0.2 2.1 1 1 0 1 1 1 1 Transcription initiation factor IIF, beta subunit DDE_Tnp_IS66_C PF13817.1 KLO15281.1 - 0.025 14.5 0.0 0.058 13.4 0.0 1.5 1 0 0 1 1 1 0 IS66 C-terminal element DUF605 PF04652.11 KLO15282.1 - 0.23 10.8 12.9 0.45 9.8 9.0 1.4 1 0 0 1 1 1 0 Vta1 like PAT1 PF09770.4 KLO15283.1 - 3.1 5.9 11.9 3.5 5.7 8.3 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 GATA PF00320.22 KLO15284.1 - 2e-15 55.8 5.1 2e-15 55.8 3.5 1.8 2 0 0 2 2 2 1 GATA zinc finger DUF605 PF04652.11 KLO15284.1 - 9.3 5.5 22.2 10 5.4 15.4 1.2 1 0 0 1 1 1 0 Vta1 like IDO PF01231.13 KLO15286.1 - 3.6e-108 361.7 0.0 4.2e-108 361.4 0.0 1.0 1 0 0 1 1 1 1 Indoleamine 2,3-dioxygenase Cytochrom_C PF00034.16 KLO15287.1 - 4.8e-09 36.9 0.1 7.6e-09 36.2 0.1 1.3 1 1 0 1 1 1 1 Cytochrome c Cytochrome_CBB3 PF13442.1 KLO15287.1 - 3e-08 33.6 2.2 4.3e-07 29.9 1.5 2.0 1 1 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C550 PF14495.1 KLO15287.1 - 2.8e-06 26.8 0.2 1.7e-05 24.2 0.1 2.0 2 0 0 2 2 2 1 Cytochrome c-550 domain Cytochrom_C1 PF02167.10 KLO15287.1 - 0.14 11.8 0.1 0.19 11.3 0.0 1.3 1 1 0 1 1 1 0 Cytochrome C1 family Dehyd-heme_bind PF09098.5 KLO15287.1 - 0.15 11.4 0.3 2.9 7.2 0.0 2.2 1 1 1 2 2 2 0 Quinohemoprotein amine dehydrogenase A, alpha subunit, haem binding ABC_tran PF00005.22 KLO15289.1 - 1.9e-50 170.7 0.0 4.1e-27 95.1 0.0 2.9 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 KLO15289.1 - 7e-50 169.9 33.1 2.3e-26 92.8 7.2 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region AAA_21 PF13304.1 KLO15289.1 - 2.1e-10 41.0 5.6 0.0032 17.4 0.7 4.7 3 2 0 4 4 4 3 AAA domain SMC_N PF02463.14 KLO15289.1 - 3.5e-06 26.4 1.4 0.0071 15.5 0.2 3.6 3 1 0 3 3 3 1 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.18 KLO15289.1 - 9.8e-06 25.5 0.1 0.12 12.3 0.0 2.9 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_25 PF13481.1 KLO15289.1 - 1.7e-05 24.2 0.6 0.016 14.6 0.0 3.0 3 0 0 3 3 3 2 AAA domain AAA_29 PF13555.1 KLO15289.1 - 0.00027 20.4 2.8 0.49 9.9 0.0 3.1 3 0 0 3 3 3 2 P-loop containing region of AAA domain DUF258 PF03193.11 KLO15289.1 - 0.00038 19.6 0.6 0.2 10.8 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 MobB PF03205.9 KLO15289.1 - 0.00092 18.9 2.0 0.43 10.2 0.1 3.4 3 0 0 3 3 3 1 Molybdopterin guanine dinucleotide synthesis protein B Miro PF08477.8 KLO15289.1 - 0.0017 18.8 1.1 2 8.9 0.2 2.9 2 0 0 2 2 2 2 Miro-like protein AAA_33 PF13671.1 KLO15289.1 - 0.0017 18.2 3.6 1.8 8.4 0.0 3.4 3 0 0 3 3 3 2 AAA domain AAA_16 PF13191.1 KLO15289.1 - 0.0035 17.3 5.6 1.5 8.7 0.4 3.8 2 1 1 3 3 3 2 AAA ATPase domain AAA_17 PF13207.1 KLO15289.1 - 0.012 16.4 1.9 6.5 7.5 0.0 3.7 4 0 0 4 4 2 0 AAA domain AAA_10 PF12846.2 KLO15289.1 - 0.047 13.1 3.7 3.7 6.8 0.2 2.6 3 0 0 3 3 3 0 AAA-like domain Zeta_toxin PF06414.7 KLO15289.1 - 0.076 12.0 1.2 6.8 5.7 0.1 2.4 2 0 0 2 2 2 0 Zeta toxin ArgK PF03308.11 KLO15289.1 - 0.083 11.6 8.2 0.48 9.1 0.2 2.9 3 0 0 3 3 3 0 ArgK protein Dynamin_N PF00350.18 KLO15289.1 - 0.15 11.8 6.8 1.4 8.7 0.3 2.9 3 0 0 3 3 3 0 Dynamin family ATP_bind_1 PF03029.12 KLO15289.1 - 0.18 11.3 1.5 15 4.9 0.1 2.7 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_30 PF13604.1 KLO15289.1 - 0.2 11.2 1.1 8.2 5.9 0.0 2.7 3 0 0 3 3 3 0 AAA domain RNA_helicase PF00910.17 KLO15289.1 - 0.22 11.7 0.1 22 5.2 0.0 3.0 3 0 0 3 3 3 0 RNA helicase AAA_23 PF13476.1 KLO15289.1 - 0.77 10.0 10.6 2.1 8.6 0.0 3.3 4 0 0 4 4 3 0 AAA domain UPF0079 PF02367.12 KLO15289.1 - 0.94 9.1 2.8 1.5 8.4 0.1 2.5 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 cobW PF02492.14 KLO15289.1 - 1.9 7.9 5.6 1.7 8.0 0.2 2.8 3 0 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain F-box-like PF12937.2 KLO15290.1 - 4e-07 29.6 0.0 1.4e-06 27.9 0.0 2.0 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KLO15290.1 - 7.8e-05 22.2 6.2 0.00012 21.5 0.0 3.3 3 0 0 3 3 3 1 F-box domain F-box-like_2 PF13013.1 KLO15290.1 - 0.035 13.8 0.1 0.097 12.4 0.1 1.8 1 1 0 1 1 1 0 F-box-like domain PG_binding_2 PF08823.6 KLO15290.1 - 0.15 12.1 1.4 8.8 6.5 0.1 3.1 3 0 0 3 3 3 0 Putative peptidoglycan binding domain F-box PF00646.28 KLO15291.1 - 1e-05 25.0 0.0 4e-05 23.1 0.0 2.1 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 KLO15291.1 - 0.0011 18.7 0.0 0.0031 17.2 0.0 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KLO15292.1 - 7.9e-06 25.3 1.5 1.1e-05 24.9 0.0 2.0 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.2 KLO15292.1 - 5.2e-05 22.8 0.0 0.00011 21.8 0.0 1.5 1 0 0 1 1 1 1 F-box-like Noc2 PF03715.8 KLO15292.1 - 0.0078 15.0 0.1 0.013 14.3 0.1 1.2 1 0 0 1 1 1 1 Noc2p family Baculo_11_kDa PF06143.6 KLO15293.1 - 0.012 14.9 0.7 0.053 12.8 0.1 2.2 2 0 0 2 2 2 0 Baculovirus 11 kDa family ABC2_membrane PF01061.19 KLO15298.1 - 8.1e-37 126.4 12.0 8.1e-37 126.4 8.3 2.3 2 0 0 2 2 2 1 ABC-2 type transporter ABC_tran PF00005.22 KLO15298.1 - 2.5e-26 92.6 0.1 7.9e-26 90.9 0.0 1.9 2 0 0 2 2 2 1 ABC transporter AAA_21 PF13304.1 KLO15298.1 - 5.4e-05 23.2 0.0 0.42 10.5 0.0 2.4 2 0 0 2 2 2 2 AAA domain ABC2_membrane_3 PF12698.2 KLO15298.1 - 0.00051 19.1 26.1 0.00051 19.1 18.1 2.6 2 1 0 2 2 2 1 ABC-2 family transporter protein DUF258 PF03193.11 KLO15298.1 - 0.0022 17.2 0.1 0.0055 15.9 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_22 PF13401.1 KLO15298.1 - 0.0049 17.0 0.0 0.011 15.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.1 KLO15298.1 - 0.0073 15.7 0.1 0.017 14.5 0.1 1.5 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 KLO15298.1 - 0.0084 16.9 0.0 0.017 15.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 KLO15298.1 - 0.011 15.7 0.0 0.02 14.9 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain AAA_29 PF13555.1 KLO15298.1 - 0.017 14.6 0.0 0.046 13.2 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_28 PF13521.1 KLO15298.1 - 0.019 14.9 0.1 0.033 14.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain NACHT PF05729.7 KLO15298.1 - 0.029 14.0 0.0 0.071 12.7 0.0 1.6 1 0 0 1 1 1 0 NACHT domain AAA PF00004.24 KLO15298.1 - 0.03 14.5 0.0 0.073 13.2 0.0 1.6 2 0 0 2 2 1 0 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.1 KLO15298.1 - 0.035 14.4 0.1 0.063 13.5 0.1 1.3 1 0 0 1 1 1 0 AAA domain MobB PF03205.9 KLO15298.1 - 0.041 13.5 0.0 0.071 12.8 0.0 1.3 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_33 PF13671.1 KLO15298.1 - 0.048 13.5 0.1 0.083 12.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.1 KLO15298.1 - 0.19 11.3 0.1 0.3 10.6 0.1 1.2 1 0 0 1 1 1 0 AAA domain Rad17 PF03215.10 KLO15298.1 - 0.39 9.3 0.0 0.61 8.7 0.0 1.2 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein NB-ARC PF00931.17 KLO15298.1 - 0.51 9.1 0.1 0.88 8.3 0.1 1.3 1 0 0 1 1 1 0 NB-ARC domain ILVD_EDD PF00920.16 KLO15299.1 - 3.2e-167 557.1 0.0 3.6e-167 556.9 0.0 1.0 1 0 0 1 1 1 1 Dehydratase family Fumble PF03630.9 KLO15301.1 - 0.049 12.4 0.0 0.064 12.1 0.0 1.1 1 0 0 1 1 1 0 Fumble Ubiquitin_2 PF14560.1 KLO15301.1 - 0.062 13.5 0.0 0.13 12.5 0.0 1.5 1 0 0 1 1 1 0 Ubiquitin-like domain LINES_N PF14694.1 KLO15301.1 - 0.12 11.6 0.0 0.17 11.1 0.0 1.2 1 0 0 1 1 1 0 Lines N-terminus UCR_TM PF02921.9 KLO15302.1 - 0.061 13.5 0.9 1.1 9.5 0.1 2.2 2 0 0 2 2 2 0 Ubiquinol cytochrome reductase transmembrane region Pkr1 PF08636.5 KLO15302.1 - 1.2 9.2 3.9 4.8 7.3 0.3 2.6 3 0 0 3 3 3 0 ER protein Pkr1 VCBS PF13517.1 KLO15303.1 - 3e-24 85.1 21.6 1.8e-10 40.9 2.2 5.6 4 1 2 6 6 6 5 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella FG-GAP PF01839.18 KLO15303.1 - 7.6e-14 50.9 20.1 0.014 15.0 0.1 7.1 7 0 0 7 7 7 6 FG-GAP repeat TcdB_toxin_midN PF12256.3 KLO15303.1 - 1.7e-05 24.3 9.2 1.5 8.2 0.1 5.7 4 2 2 6 6 6 4 Insecticide toxin TcdB middle/N-terminal region EF-hand_5 PF13202.1 KLO15303.1 - 9.2 5.8 13.9 2.1 7.8 0.1 3.9 4 0 0 4 4 4 0 EF hand CPSF_A PF03178.10 KLO15305.1 - 0.019 14.0 0.0 0.027 13.5 0.0 1.4 1 1 0 1 1 1 0 CPSF A subunit region Glyoxalase_3 PF13468.1 KLO15306.1 - 6.5e-28 97.7 0.0 1.3e-27 96.8 0.0 1.5 1 0 0 1 1 1 1 Glyoxalase-like domain F-box-like PF12937.2 KLO15308.1 - 8.6e-05 22.1 0.1 0.00034 20.2 0.1 2.1 1 1 0 1 1 1 1 F-box-like F-box-like PF12937.2 KLO15309.1 - 0.00053 19.6 0.2 0.0017 18.0 0.1 1.9 1 0 0 1 1 1 1 F-box-like Syndecan PF01034.15 KLO15311.1 - 0.01 15.4 0.1 0.018 14.6 0.0 1.3 1 0 0 1 1 1 0 Syndecan domain AA_permease_2 PF13520.1 KLO15311.1 - 0.051 12.1 0.9 0.19 10.2 0.0 1.9 2 0 0 2 2 2 0 Amino acid permease Peptidase_S10 PF00450.17 KLO15312.1 - 8.9e-184 611.4 4.1 2.5e-96 323.3 0.3 2.0 2 0 0 2 2 2 2 Serine carboxypeptidase UPAR_LY6 PF00021.16 KLO15312.1 - 2.2 8.7 6.8 16 6.0 0.9 2.7 2 0 0 2 2 2 0 u-PAR/Ly-6 domain Ras PF00071.17 KLO15313.1 - 8.1e-46 155.3 0.0 9.8e-46 155.0 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KLO15313.1 - 6.4e-18 65.3 0.0 9.7e-18 64.7 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KLO15313.1 - 4.4e-09 35.8 0.0 6.8e-09 35.1 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 KLO15313.1 - 6.2e-05 22.5 0.0 0.00085 18.8 0.0 2.0 1 1 0 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 KLO15313.1 - 0.0019 18.1 0.0 0.0035 17.2 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase Cloacin_immun PF03513.9 KLO15313.1 - 0.06 13.3 0.2 4.7 7.3 0.0 2.9 2 1 1 3 3 3 0 Cloacin immunity protein DUF1448 PF07289.6 KLO15313.1 - 0.14 11.0 0.0 0.18 10.6 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1448) Gtr1_RagA PF04670.7 KLO15313.1 - 0.14 11.2 0.0 0.17 11.0 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region DUF1691 PF07950.6 KLO15314.1 - 4.3e-09 36.2 0.5 3.1e-05 23.8 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF1691) KOW PF00467.24 KLO15316.1 - 6.5e-13 47.8 17.0 0.00071 19.1 0.8 5.4 5 0 0 5 5 5 4 KOW motif Spt5-NGN PF03439.8 KLO15316.1 - 1.7e-12 46.9 0.0 3.5e-12 45.9 0.0 1.6 1 0 0 1 1 1 1 Early transcription elongation factor of RNA pol II, NGN section DUF4438 PF14505.1 KLO15316.1 - 0.0043 15.8 3.3 0.053 12.2 0.0 2.5 1 1 1 2 2 2 2 Domain of unknown function (DUF4438) E1-E2_ATPase PF00122.15 KLO15317.1 - 7.5e-59 198.5 3.3 2.2e-58 197.0 1.8 2.1 1 1 1 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.21 KLO15317.1 - 4.1e-30 105.8 0.0 9.7e-30 104.5 0.0 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_C PF00689.16 KLO15317.1 - 9.8e-22 77.3 23.9 1.7e-17 63.5 1.6 3.8 3 1 1 4 4 4 2 Cation transporting ATPase, C-terminus Hydrolase_like2 PF13246.1 KLO15317.1 - 9.8e-20 70.3 0.0 2.1e-19 69.2 0.0 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Cation_ATPase_N PF00690.21 KLO15317.1 - 5.8e-15 54.5 0.0 1.3e-14 53.3 0.0 1.7 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus HAD PF12710.2 KLO15317.1 - 2.1e-13 50.8 0.0 5.5e-13 49.5 0.0 1.8 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 KLO15317.1 - 6.8e-05 22.5 0.7 0.033 13.7 0.3 2.4 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase OPT PF03169.10 KLO15319.1 - 1.7e-197 657.7 53.0 2e-197 657.5 36.8 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein HMG_box PF00505.14 KLO15320.1 - 5.3e-14 52.2 5.9 1.3e-13 51.0 4.1 1.6 1 1 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 KLO15320.1 - 1.9e-10 40.9 1.6 2.1e-10 40.8 1.1 1.1 1 0 0 1 1 1 1 HMG-box domain HMG_box_5 PF14887.1 KLO15320.1 - 0.05 13.3 4.3 0.077 12.7 3.0 1.5 1 1 0 1 1 1 0 HMG (high mobility group) box 5 COX4 PF02936.9 KLO15320.1 - 0.14 11.9 0.9 0.18 11.5 0.6 1.1 1 0 0 1 1 1 0 Cytochrome c oxidase subunit IV Peptidase_S10 PF00450.17 KLO15321.1 - 2.9e-104 349.5 0.2 3.6e-104 349.2 0.1 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Abhydrolase_6 PF12697.2 KLO15321.1 - 7.8e-05 22.6 0.0 0.0011 18.8 0.0 2.5 2 1 0 2 2 2 1 Alpha/beta hydrolase family F-box-like PF12937.2 KLO15323.1 - 0.00019 21.1 0.3 0.00052 19.6 0.2 1.9 1 0 0 1 1 1 1 F-box-like F-box-like_2 PF13013.1 KLO15323.1 - 0.02 14.5 0.0 0.047 13.4 0.0 1.6 1 0 0 1 1 1 0 F-box-like domain F-box-like PF12937.2 KLO15325.1 - 0.00066 19.3 0.4 0.0029 17.2 0.1 2.3 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 KLO15325.1 - 0.09 12.4 1.1 0.39 10.4 0.1 2.6 2 0 0 2 2 2 0 F-box domain F-box-like PF12937.2 KLO15326.1 - 1.4e-05 24.7 1.4 3.7e-05 23.3 0.2 2.3 2 0 0 2 2 2 1 F-box-like F-box-like PF12937.2 KLO15327.1 - 2.2e-06 27.3 4.2 3.5e-06 26.6 0.1 3.2 3 0 0 3 3 3 1 F-box-like F-box PF00646.28 KLO15327.1 - 0.053 13.1 0.1 0.26 11.0 0.1 2.3 1 0 0 1 1 1 0 F-box domain AsmA_1 PF13109.1 KLO15327.1 - 0.2 10.9 0.5 1.8 7.8 0.0 2.2 2 0 0 2 2 2 0 AsmA-like C-terminal region LRR_4 PF12799.2 KLO15327.1 - 6.5 6.4 7.4 5.7 6.6 0.1 3.8 3 1 1 4 4 4 0 Leucine Rich repeats (2 copies) F-box-like PF12937.2 KLO15328.1 - 5.5e-07 29.2 1.7 1.4e-06 27.8 0.5 2.3 2 0 0 2 2 2 1 F-box-like DUF1148 PF06618.6 KLO15328.1 - 0.0057 16.5 0.3 0.014 15.3 0.2 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1148) F-box PF00646.28 KLO15328.1 - 0.04 13.5 0.5 0.04 13.5 0.4 2.3 2 0 0 2 2 2 0 F-box domain F-box-like PF12937.2 KLO15329.1 - 6.7e-08 32.1 2.6 2.2e-07 30.4 0.3 2.7 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 KLO15329.1 - 0.0048 16.5 0.9 0.0048 16.5 0.6 3.1 3 0 0 3 3 3 1 F-box domain LRR_8 PF13855.1 KLO15329.1 - 0.33 10.7 9.2 14 5.5 0.0 4.5 3 1 1 4 4 4 0 Leucine rich repeat LRR_4 PF12799.2 KLO15329.1 - 0.67 9.6 10.7 0.17 11.5 0.1 4.2 3 1 1 4 4 4 0 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 KLO15329.1 - 3.3 8.0 6.1 3 8.2 0.2 4.0 3 0 0 3 3 3 0 Leucine Rich Repeat F-box-like PF12937.2 KLO15330.1 - 2.1e-08 33.7 3.0 1.1e-07 31.5 0.4 3.0 3 0 0 3 3 3 1 F-box-like F-box PF00646.28 KLO15330.1 - 0.018 14.6 1.4 0.018 14.6 1.0 2.2 2 0 0 2 2 2 0 F-box domain LRR_8 PF13855.1 KLO15330.1 - 0.061 13.0 6.4 1.7 8.4 0.2 4.0 2 1 1 3 3 3 0 Leucine rich repeat F-box-like PF12937.2 KLO15333.1 - 3.3e-06 26.7 0.0 9.3e-06 25.2 0.0 1.8 1 0 0 1 1 1 1 F-box-like FPN1 PF06963.7 KLO15334.1 - 4.2e-122 407.6 17.2 4.9e-122 407.4 11.9 1.0 1 0 0 1 1 1 1 Ferroportin1 (FPN1) F-box-like PF12937.2 KLO15335.1 - 1.6e-08 34.1 0.0 5.1e-08 32.5 0.0 1.9 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.2 KLO15335.1 - 0.0005 19.6 2.6 0.47 10.1 0.1 2.9 2 0 0 2 2 2 2 Leucine Rich repeats (2 copies) F-box-like PF12937.2 KLO15336.1 - 1.1e-07 31.4 0.2 2.2e-07 30.4 0.2 1.6 1 0 0 1 1 1 1 F-box-like COG5 PF10392.4 KLO15336.1 - 0.096 12.6 0.1 0.2 11.6 0.1 1.5 1 0 0 1 1 1 0 Golgi transport complex subunit 5 LRR_4 PF12799.2 KLO15336.1 - 0.15 11.6 2.7 0.34 10.5 0.2 2.9 3 0 0 3 3 3 0 Leucine Rich repeats (2 copies) F-box-like PF12937.2 KLO15337.1 - 2e-07 30.6 0.4 5e-07 29.3 0.3 1.7 1 1 0 1 1 1 1 F-box-like Ras PF00071.17 KLO15338.1 - 6.8e-53 178.3 0.0 7.8e-53 178.1 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KLO15338.1 - 2.3e-18 66.7 0.0 3.4e-18 66.2 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KLO15338.1 - 2e-07 30.4 0.0 2.6e-07 30.0 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 KLO15338.1 - 0.00042 19.8 0.0 0.0046 16.4 0.0 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain F-box-like PF12937.2 KLO15339.1 - 6.9e-09 35.2 3.2 1.8e-08 33.9 2.2 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KLO15339.1 - 0.00053 19.5 2.8 0.0011 18.5 1.1 2.3 2 0 0 2 2 2 1 F-box domain F-box-like_2 PF13013.1 KLO15339.1 - 1.6 8.4 7.9 0.19 11.4 0.1 2.8 3 0 0 3 3 3 0 F-box-like domain Ras PF00071.17 KLO15340.1 - 4.6e-58 195.1 0.2 6.3e-58 194.7 0.2 1.2 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KLO15340.1 - 7.3e-17 61.9 0.1 1.4e-16 61.0 0.0 1.5 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KLO15340.1 - 1e-09 37.8 0.0 1.4e-09 37.4 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 KLO15340.1 - 0.0011 18.4 0.0 0.0014 18.1 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_22 PF13401.1 KLO15340.1 - 0.0013 18.9 0.0 0.0033 17.5 0.0 1.6 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.18 KLO15340.1 - 0.0024 17.8 0.4 0.0086 16.0 0.3 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 KLO15340.1 - 0.0038 16.3 0.0 0.006 15.7 0.0 1.4 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_29 PF13555.1 KLO15340.1 - 0.0053 16.2 0.0 0.01 15.3 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_14 PF13173.1 KLO15340.1 - 0.022 14.6 0.0 0.1 12.4 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA_32 PF13654.1 KLO15340.1 - 0.057 12.0 0.1 0.16 10.5 0.0 1.7 1 1 1 2 2 2 0 AAA domain Septin PF00735.13 KLO15340.1 - 0.086 11.8 0.0 0.15 11.0 0.0 1.3 1 0 0 1 1 1 0 Septin DUF4265 PF14085.1 KLO15340.1 - 0.12 12.1 0.0 8.2 6.2 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4265) AAA_16 PF13191.1 KLO15340.1 - 0.16 11.9 0.1 0.38 10.7 0.1 1.8 1 1 0 1 1 1 0 AAA ATPase domain p450 PF00067.17 KLO15341.1 - 2.8e-56 190.9 0.0 7.9e-56 189.5 0.0 1.7 1 1 0 1 1 1 1 Cytochrome P450 Zn_clus PF00172.13 KLO15342.1 - 1e-08 34.9 13.2 1.7e-08 34.2 9.1 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 KLO15342.1 - 1.3e-05 24.2 1.4 1.3e-05 24.2 1.0 2.6 2 1 0 2 2 2 1 Fungal specific transcription factor domain ADK PF00406.17 KLO15345.1 - 2.1e-60 203.0 0.0 2.6e-60 202.6 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase ADK_lid PF05191.9 KLO15345.1 - 2.9e-14 52.4 0.0 8.6e-14 50.9 0.0 1.8 2 0 0 2 2 2 1 Adenylate kinase, active site lid AAA_33 PF13671.1 KLO15345.1 - 3.4e-05 23.7 0.0 7.5e-05 22.6 0.0 1.5 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 KLO15345.1 - 0.00086 20.1 0.0 0.0015 19.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 KLO15345.1 - 0.0016 17.5 0.0 0.0025 16.9 0.0 1.3 1 0 0 1 1 1 1 Zeta toxin PolC_DP2 PF03833.8 KLO15345.1 - 0.1 10.2 0.0 0.12 9.9 0.0 1.1 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 CMD PF02627.15 KLO15346.1 - 0.011 15.5 0.1 0.02 14.7 0.0 1.4 1 0 0 1 1 1 0 Carboxymuconolactone decarboxylase family DDOST_48kD PF03345.9 KLO15347.1 - 9.7e-102 340.6 0.0 1.2e-101 340.3 0.0 1.0 1 0 0 1 1 1 1 Oligosaccharyltransferase 48 kDa subunit beta F-box-like PF12937.2 KLO15348.1 - 1.2e-07 31.3 0.0 3.3e-07 29.9 0.0 1.8 1 1 0 1 1 1 1 F-box-like DUF445 PF04286.7 KLO15350.1 - 0.079 12.4 0.3 0.1 12.0 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF445) F-box-like PF12937.2 KLO15351.1 - 1.5e-07 31.0 0.1 1.5e-07 31.0 0.0 3.1 4 0 0 4 4 4 1 F-box-like LRR_4 PF12799.2 KLO15351.1 - 0.19 11.3 4.2 1.7 8.3 0.9 3.4 4 0 0 4 4 4 0 Leucine Rich repeats (2 copies) F-box-like PF12937.2 KLO15353.1 - 1e-07 31.5 0.2 1e-07 31.5 0.2 2.6 3 0 0 3 3 3 1 F-box-like LRR_4 PF12799.2 KLO15353.1 - 0.027 14.0 0.1 5.2 6.7 0.0 3.4 3 0 0 3 3 3 0 Leucine Rich repeats (2 copies) STAS_2 PF13466.1 KLO15353.1 - 0.057 13.4 0.5 0.2 11.7 0.0 2.3 2 0 0 2 2 2 0 STAS domain LRR_8 PF13855.1 KLO15356.1 - 0.014 15.1 0.0 0.047 13.4 0.0 1.9 1 0 0 1 1 1 0 Leucine rich repeat DDE_1 PF03184.14 KLO15358.1 - 0.00035 19.7 0.0 0.0005 19.2 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease CDI PF02234.14 KLO15359.1 - 0.079 12.7 0.5 0.12 12.1 0.2 1.5 2 0 0 2 2 2 0 Cyclin-dependent kinase inhibitor BAR PF03114.13 KLO15360.1 - 2e-47 161.6 6.8 2.5e-47 161.3 4.7 1.1 1 0 0 1 1 1 1 BAR domain Arfaptin PF06456.8 KLO15360.1 - 0.00099 18.5 8.6 0.0085 15.4 6.0 2.0 1 1 0 1 1 1 1 Arfaptin-like domain Sigma_1s PF02454.11 KLO15360.1 - 0.0071 16.0 0.0 4.6 7.0 0.0 2.3 2 0 0 2 2 2 2 Sigma 1s protein Mnd1 PF03962.10 KLO15360.1 - 0.0075 15.9 1.9 1.2 8.7 0.0 2.2 2 0 0 2 2 2 2 Mnd1 family AAA_13 PF13166.1 KLO15360.1 - 0.014 13.8 2.7 0.02 13.4 1.8 1.3 1 0 0 1 1 1 0 AAA domain Clathrin_lg_ch PF01086.12 KLO15362.1 - 1.5e-42 146.0 1.3 2.3e-38 132.3 0.5 2.1 2 0 0 2 2 2 2 Clathrin light chain YbbR PF07949.7 KLO15362.1 - 0.11 12.6 0.2 16 5.7 0.0 2.4 2 0 0 2 2 2 0 YbbR-like protein rve_3 PF13683.1 KLO15362.1 - 0.13 11.7 0.3 0.27 10.7 0.2 1.5 1 0 0 1 1 1 0 Integrase core domain Selenoprotein_S PF06936.6 KLO15362.1 - 0.29 10.6 3.2 0.4 10.1 2.2 1.2 1 0 0 1 1 1 0 Selenoprotein S (SelS) YqhG PF11079.3 KLO15362.1 - 0.44 9.3 2.4 0.58 8.9 1.7 1.1 1 0 0 1 1 1 0 Bacterial protein YqhG of unknown function NUDIX PF00293.23 KLO15364.1 - 7.3e-18 64.5 0.0 1.1e-17 63.8 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain NUDIX-like PF09296.6 KLO15364.1 - 9.9e-13 48.2 0.0 1.8e-12 47.4 0.0 1.5 1 0 0 1 1 1 1 NADH pyrophosphatase-like rudimentary NUDIX domain zf-NADH-PPase PF09297.6 KLO15364.1 - 1.3e-05 24.6 0.6 2.4e-05 23.7 0.4 1.4 1 0 0 1 1 1 1 NADH pyrophosphatase zinc ribbon domain tRNA-synt_1e PF01406.14 KLO15365.1 - 3.1e-121 404.1 0.2 3.1e-121 404.1 0.1 1.7 2 0 0 2 2 2 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1g PF09334.6 KLO15365.1 - 3.3e-08 32.5 0.7 3.6e-05 22.5 0.0 2.4 2 0 0 2 2 2 2 tRNA synthetases class I (M) tRNA-synt_1 PF00133.17 KLO15365.1 - 2.6e-06 25.7 0.0 0.0005 18.2 0.0 2.4 2 0 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) DALR_2 PF09190.6 KLO15365.1 - 7.1e-05 22.9 1.4 0.00018 21.6 0.0 2.4 2 0 0 2 2 2 1 DALR domain tRNA-synt_1c PF00749.16 KLO15365.1 - 0.048 12.3 1.6 0.98 8.0 0.0 2.9 3 0 0 3 3 3 0 tRNA synthetases class I (E and Q), catalytic domain Kelch_4 PF13418.1 KLO15366.1 - 3.7e-25 87.4 13.1 2.8e-07 30.1 0.1 6.5 5 1 1 6 6 6 6 Galactose oxidase, central domain DUF4110 PF13422.1 KLO15366.1 - 2.1e-23 81.9 0.4 2.1e-23 81.9 0.3 2.7 2 0 0 2 2 2 1 Domain of unknown function (DUF4110) Kelch_3 PF13415.1 KLO15366.1 - 2.9e-23 81.4 9.5 7.2e-09 35.5 0.1 6.5 7 0 0 7 7 7 3 Galactose oxidase, central domain Kelch_6 PF13964.1 KLO15366.1 - 1.1e-17 63.3 14.2 4.6e-06 26.5 0.3 6.2 5 1 1 6 6 6 3 Kelch motif Kelch_1 PF01344.20 KLO15366.1 - 6.1e-16 57.7 12.5 2.4e-06 26.9 0.5 5.1 5 1 0 5 5 5 4 Kelch motif Kelch_2 PF07646.10 KLO15366.1 - 1.5e-12 46.7 11.7 3.4e-05 23.4 0.2 5.0 4 1 0 4 4 4 4 Kelch motif Kelch_5 PF13854.1 KLO15366.1 - 1.6e-10 40.6 18.0 0.003 17.4 0.1 5.8 6 0 0 6 6 6 4 Kelch motif Mito_carr PF00153.22 KLO15367.1 - 3.3e-65 215.8 3.0 4.5e-22 77.5 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein CoA_binding_2 PF13380.1 KLO15368.1 - 3.1e-30 104.7 0.0 3.8e-30 104.4 0.0 1.1 1 0 0 1 1 1 1 CoA binding domain CoA_binding PF02629.14 KLO15368.1 - 0.023 15.1 0.0 0.038 14.4 0.0 1.2 1 0 0 1 1 1 0 CoA binding domain CBM27 PF09212.5 KLO15368.1 - 0.15 12.0 0.0 0.17 11.9 0.0 1.1 1 0 0 1 1 1 0 Carbohydrate binding module 27 zf-HIT PF04438.11 KLO15369.1 - 1e-08 34.6 12.2 1.4e-08 34.1 8.5 1.2 1 0 0 1 1 1 1 HIT zinc finger zf-MYND PF01753.13 KLO15369.1 - 0.016 15.0 9.4 0.029 14.2 6.5 1.4 1 0 0 1 1 1 0 MYND finger zf-B_box PF00643.19 KLO15369.1 - 1.1 9.2 7.0 1.7 8.6 4.8 1.3 1 0 0 1 1 1 0 B-box zinc finger Peroxidase_2 PF01328.12 KLO15370.1 - 4.9e-20 71.4 0.1 7.2e-20 70.8 0.0 1.4 2 0 0 2 2 2 1 Peroxidase, family 2 Cyt-b5 PF00173.23 KLO15372.1 - 1.9e-09 37.2 0.1 2.3e-09 36.9 0.1 1.1 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain DIOX_N PF14226.1 KLO15373.1 - 7.9e-26 90.8 0.0 1.2e-25 90.2 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 KLO15373.1 - 1.8e-15 56.9 0.0 4.2e-15 55.8 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Lipoprotein_X PF03305.8 KLO15373.1 - 0.086 12.1 0.0 0.14 11.5 0.0 1.2 1 0 0 1 1 1 0 Mycoplasma MG185/MG260 protein DIOX_N PF14226.1 KLO15374.1 - 5.7e-24 84.8 0.0 9.3e-24 84.1 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 KLO15374.1 - 5.7e-16 58.6 0.0 1.1e-15 57.7 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Peroxidase_2 PF01328.12 KLO15375.1 - 7.4e-21 74.1 0.1 1.2e-20 73.4 0.1 1.5 1 1 0 1 1 1 1 Peroxidase, family 2 LRR_4 PF12799.2 KLO15376.1 - 2.8e-55 183.1 59.0 7.2e-08 31.8 0.4 14.1 7 4 7 15 15 15 14 Leucine Rich repeats (2 copies) PP2C PF00481.16 KLO15376.1 - 2.1e-47 161.6 0.0 3.4e-47 161.0 0.0 1.3 1 0 0 1 1 1 1 Protein phosphatase 2C LRR_8 PF13855.1 KLO15376.1 - 1.8e-46 155.7 62.5 5.2e-12 45.3 0.8 10.7 5 2 7 12 12 12 11 Leucine rich repeat Guanylate_cyc PF00211.15 KLO15376.1 - 4.2e-26 91.4 0.0 8.4e-26 90.4 0.0 1.4 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain LRR_1 PF00560.28 KLO15376.1 - 4.2e-26 86.9 66.2 0.019 14.9 0.1 20.6 20 1 0 20 20 20 11 Leucine Rich Repeat LRR_7 PF13504.1 KLO15376.1 - 1.5e-10 39.4 62.5 1.2 9.6 0.0 18.3 20 0 0 20 20 20 7 Leucine rich repeat LRR_6 PF13516.1 KLO15376.1 - 7.4e-06 25.5 59.3 4.3 7.7 0.4 16.8 18 1 0 18 18 18 4 Leucine Rich repeat LRR_5 PF13306.1 KLO15376.1 - 0.00013 21.6 7.0 0.0063 16.2 0.0 3.6 3 1 1 4 4 4 2 Leucine rich repeats (6 copies) Mg_trans_NIPA PF05653.9 KLO15377.1 - 2.6e-82 276.1 25.3 3.6e-82 275.6 17.5 1.1 1 0 0 1 1 1 1 Magnesium transporter NIPA EmrE PF13536.1 KLO15377.1 - 1.1e-06 28.8 7.6 1.1e-06 28.8 5.2 3.6 2 2 1 4 4 4 1 Multidrug resistance efflux transporter EamA PF00892.15 KLO15377.1 - 8.6e-06 25.8 13.2 8.6e-06 25.8 9.1 3.7 2 2 1 3 3 3 1 EamA-like transporter family DUF2208 PF09973.4 KLO15377.1 - 0.29 10.3 5.1 0.54 9.4 3.5 1.4 1 0 0 1 1 1 0 Predicted membrane protein (DUF2208) PWWP PF00855.12 KLO15379.1 - 1.5e-14 53.9 0.1 1.5e-14 53.9 0.0 2.9 1 1 1 2 2 2 1 PWWP domain Med26 PF08711.6 KLO15379.1 - 0.00066 19.1 0.0 0.0019 17.6 0.0 1.8 1 1 0 1 1 1 1 TFIIS helical bundle-like domain FRG2 PF15315.1 KLO15379.1 - 0.14 12.1 13.9 0.35 10.8 9.6 1.8 1 0 0 1 1 1 0 Facioscapulohumeral muscular dystrophy candidate 2 Glyoxalase PF00903.20 KLO15380.1 - 1.8e-36 124.9 6.1 4.4e-22 78.4 0.5 2.2 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.2 KLO15380.1 - 4.7e-28 97.9 1.6 2.3e-14 53.9 0.1 2.3 2 0 0 2 2 2 2 Glyoxalase-like domain Glyoxalase_4 PF13669.1 KLO15380.1 - 2e-13 50.3 1.2 1.5e-06 28.1 0.1 3.2 2 1 1 3 3 3 3 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_3 PF13468.1 KLO15380.1 - 4.1e-05 23.5 0.0 0.24 11.2 0.0 2.9 2 1 0 3 3 3 2 Glyoxalase-like domain DAP_epimerase PF01678.14 KLO15380.1 - 0.00026 20.8 0.2 1.1 9.2 0.0 2.8 2 0 0 2 2 2 2 Diaminopimelate epimerase Toxin_67 PF15545.1 KLO15380.1 - 6.4 6.7 8.0 11 5.9 0.3 3.3 3 1 1 4 4 4 0 Putative toxin 67 Mg_trans_NIPA PF05653.9 KLO15381.1 - 2.2e-83 279.6 21.4 2.9e-83 279.2 14.8 1.0 1 0 0 1 1 1 1 Magnesium transporter NIPA EamA PF00892.15 KLO15381.1 - 4.3e-07 30.0 8.3 4.3e-07 30.0 5.8 3.5 2 2 1 3 3 3 1 EamA-like transporter family EmrE PF13536.1 KLO15381.1 - 0.00026 21.1 5.9 0.00026 21.1 4.1 3.4 2 1 0 3 3 3 1 Multidrug resistance efflux transporter TPR_1 PF00515.23 KLO15382.1 - 2.4e-28 96.5 6.1 1e-05 24.9 1.3 6.9 7 0 0 7 7 7 5 Tetratricopeptide repeat TPR_11 PF13414.1 KLO15382.1 - 2.3e-25 88.0 12.9 3.1e-09 36.3 1.1 6.1 5 1 1 6 6 6 5 TPR repeat TPR_2 PF07719.12 KLO15382.1 - 1.7e-20 71.2 13.8 0.0028 17.4 1.8 8.0 8 0 0 8 8 8 5 Tetratricopeptide repeat APC8 PF04049.8 KLO15382.1 - 5.9e-17 61.7 0.8 1.3e-16 60.6 0.6 1.5 1 0 0 1 1 1 1 Anaphase promoting complex subunit 8 / Cdc23 TPR_8 PF13181.1 KLO15382.1 - 1.9e-16 58.5 12.0 0.006 16.2 0.0 8.1 7 1 2 9 9 9 5 Tetratricopeptide repeat TPR_14 PF13428.1 KLO15382.1 - 1.7e-12 46.7 9.3 0.13 13.0 0.0 8.1 5 1 3 8 8 8 4 Tetratricopeptide repeat TPR_16 PF13432.1 KLO15382.1 - 2.5e-12 47.1 12.3 1.3e-05 25.7 0.8 7.5 5 1 2 8 8 8 3 Tetratricopeptide repeat TPR_12 PF13424.1 KLO15382.1 - 3.2e-12 46.2 18.7 0.0018 18.1 0.4 7.0 4 1 5 9 9 9 5 Tetratricopeptide repeat TPR_17 PF13431.1 KLO15382.1 - 1.1e-11 43.9 1.1 0.11 12.7 0.1 7.8 9 0 0 9 9 8 1 Tetratricopeptide repeat TPR_7 PF13176.1 KLO15382.1 - 2.2e-06 27.0 15.4 0.94 9.4 0.0 7.1 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_9 PF13371.1 KLO15382.1 - 2.8e-05 23.8 6.6 0.0012 18.6 1.7 4.0 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_19 PF14559.1 KLO15382.1 - 0.00043 20.5 11.9 3 8.2 0.2 5.9 4 1 2 6 6 6 2 Tetratricopeptide repeat TPR_6 PF13174.1 KLO15382.1 - 0.0016 18.7 15.6 30 5.3 0.5 8.0 8 0 0 8 8 8 0 Tetratricopeptide repeat ChAPs PF09295.5 KLO15382.1 - 0.085 11.6 0.0 2.5 6.7 0.0 2.6 2 1 1 3 3 3 0 ChAPs (Chs5p-Arf1p-binding proteins) MARVEL PF01284.18 KLO15384.1 - 5.1e-06 26.3 7.6 7.1e-06 25.9 5.3 1.1 1 0 0 1 1 1 1 Membrane-associating domain DUF4133 PF13571.1 KLO15384.1 - 0.28 11.4 2.8 0.72 10.1 0.0 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4133) FAD_binding_4 PF01565.18 KLO15385.1 - 3.2e-14 52.5 2.5 6.9e-14 51.5 1.7 1.6 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 KLO15385.1 - 4.4e-09 36.0 0.0 9e-09 35.1 0.0 1.6 1 0 0 1 1 1 1 Berberine and berberine like Tetraspannin PF00335.15 KLO15386.1 - 2.2e-05 23.8 13.7 4.3e-05 22.9 9.5 1.5 1 1 0 1 1 1 1 Tetraspanin family DUF1746 PF08508.5 KLO15387.1 - 1.6e-05 24.7 0.1 3.6e-05 23.6 0.1 1.6 1 1 0 1 1 1 1 Fungal domain of unknown function (DUF1746) zf-CSL PF05207.8 KLO15387.1 - 0.048 13.1 0.0 0.085 12.3 0.0 1.4 1 0 0 1 1 1 0 CSL zinc finger UPF0203 PF05254.7 KLO15388.1 - 0.00015 21.5 3.3 0.0003 20.5 2.3 1.5 1 1 0 1 1 1 1 Uncharacterised protein family (UPF0203) Cmc1 PF08583.5 KLO15388.1 - 0.0022 17.7 3.8 0.0031 17.2 2.7 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like CHCH PF06747.8 KLO15388.1 - 0.011 15.5 3.0 0.027 14.3 2.1 1.6 1 1 0 1 1 1 0 CHCH domain COX17 PF05051.8 KLO15388.1 - 0.014 15.4 3.4 0.025 14.6 2.3 1.4 1 1 0 1 1 1 0 Cytochrome C oxidase copper chaperone (COX17) COX6B PF02297.12 KLO15388.1 - 0.032 14.2 1.2 0.043 13.8 0.8 1.2 1 0 0 1 1 1 0 Cytochrome oxidase c subunit VIb NDUF_B7 PF05676.8 KLO15388.1 - 0.046 13.1 1.2 0.061 12.7 0.8 1.1 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) UCR_hinge PF02320.11 KLO15388.1 - 0.075 12.9 1.0 0.086 12.7 0.7 1.1 1 0 0 1 1 1 0 Ubiquinol-cytochrome C reductase hinge protein GCK PF07802.6 KLO15388.1 - 2 8.5 6.3 1.6 8.9 3.3 1.6 1 1 0 1 1 1 0 GCK domain Sybindin PF04099.7 KLO15389.1 - 3.6e-18 65.6 0.0 5.7e-18 65.0 0.0 1.3 1 1 0 1 1 1 1 Sybindin-like family Syntaxin-18_N PF10496.4 KLO15389.1 - 0.052 13.3 0.0 0.09 12.6 0.0 1.3 1 0 0 1 1 1 0 SNARE-complex protein Syntaxin-18 N-terminus Ubie_methyltran PF01209.13 KLO15389.1 - 0.098 11.7 0.0 0.13 11.3 0.0 1.1 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family SNF2_N PF00176.18 KLO15390.1 - 1e-62 211.6 0.1 1.5e-62 211.0 0.1 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 KLO15390.1 - 3.2e-14 52.5 0.0 8.6e-14 51.1 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 KLO15390.1 - 9e-06 25.6 0.0 1.7e-05 24.6 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit HHH_3 PF12836.2 KLO15390.1 - 7e-05 22.6 0.0 0.00023 21.0 0.0 1.8 1 0 0 1 1 1 1 Helix-hairpin-helix motif DEAD PF00270.24 KLO15390.1 - 0.0011 18.4 0.0 0.0032 16.9 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Alba PF01918.16 KLO15391.1 - 0.13 11.8 0.0 0.21 11.2 0.0 1.3 1 0 0 1 1 1 0 Alba Mito_carr PF00153.22 KLO15393.1 - 4.3e-12 45.5 0.0 1.4e-05 24.6 0.0 2.6 2 1 0 2 2 2 2 Mitochondrial carrier protein Zn_clus PF00172.13 KLO15394.1 - 2.7e-07 30.3 6.1 5.5e-07 29.3 4.2 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RPA PF10134.4 KLO15395.1 - 0.13 11.5 0.1 0.19 10.9 0.0 1.2 1 0 0 1 1 1 0 Replication initiator protein A zf-CCCH PF00642.19 KLO15396.1 - 7.8e-14 50.9 15.6 4.4e-07 29.4 1.9 2.4 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) RRM_5 PF13893.1 KLO15396.1 - 0.00024 20.8 0.0 0.00037 20.2 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 KLO15396.1 - 0.0011 18.5 0.0 0.0026 17.3 0.0 1.6 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CART PF06373.6 KLO15396.1 - 0.85 9.6 3.9 6.6 6.7 0.4 2.8 3 0 0 3 3 3 0 Cocaine and amphetamine regulated transcript protein (CART) Alg14 PF08660.6 KLO15397.1 - 5.9e-54 182.5 0.0 6.6e-54 182.4 0.0 1.0 1 0 0 1 1 1 1 Oligosaccharide biosynthesis protein Alg14 like GLTSCR1 PF15249.1 KLO15398.1 - 8.7e-20 70.8 0.1 1.3e-19 70.3 0.1 1.2 1 0 0 1 1 1 1 Glioma tumor suppressor candidate region CATSPERD PF15020.1 KLO15399.1 - 1.3 6.9 0.1 2 6.3 0.0 1.1 1 0 0 1 1 1 0 Cation channel sperm-associated protein subunit delta Med3 PF11593.3 KLO15400.1 - 0.68 9.1 11.6 1.1 8.4 8.1 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Glyco_hydro_2 PF00703.16 KLO15401.1 - 5.5e-05 23.5 0.0 0.00035 21.0 0.0 2.1 2 0 0 2 2 2 1 Glycosyl hydrolases family 2 Ank_4 PF13637.1 KLO15402.1 - 1e-11 45.0 1.0 4.2e-07 30.2 0.2 2.7 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.2 KLO15402.1 - 1.2e-09 38.3 0.0 2.4e-09 37.4 0.0 1.4 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 KLO15402.1 - 4.5e-06 26.1 0.0 1.3e-05 24.7 0.0 1.8 1 0 0 1 1 1 1 Ankyrin repeat Ank_5 PF13857.1 KLO15402.1 - 3.4e-05 23.9 0.1 8e-05 22.7 0.1 1.6 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 KLO15402.1 - 0.00071 19.5 1.1 0.0094 16.1 0.0 3.2 4 0 0 4 4 4 1 Ankyrin repeat Ribosomal_L11_N PF03946.9 KLO15403.1 - 1.8e-17 62.5 0.2 3e-17 61.8 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.14 KLO15403.1 - 6.1e-12 45.4 0.4 1.1e-11 44.7 0.3 1.4 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain Pab87_oct PF13969.1 KLO15403.1 - 0.098 12.7 0.0 0.27 11.3 0.0 1.7 1 1 0 1 1 1 0 Pab87 octamerisation domain Cyclin PF08613.6 KLO15404.1 - 7.4e-31 107.5 0.1 1.1e-30 106.9 0.0 1.4 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.18 KLO15404.1 - 0.00068 19.1 0.0 0.001 18.6 0.0 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain PseudoU_synth_2 PF00849.17 KLO15405.1 - 1.1e-27 96.8 0.0 1.9e-27 96.1 0.0 1.4 1 0 0 1 1 1 1 RNA pseudouridylate synthase WD40 PF00400.27 KLO15406.1 - 6e-55 181.2 25.1 8.9e-12 44.4 0.1 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 KLO15406.1 - 0.00016 19.9 4.8 0.019 13.0 1.0 3.1 1 1 1 2 2 2 2 Nucleoporin Nup120/160 DUF1513 PF07433.6 KLO15406.1 - 0.00023 20.1 0.0 0.021 13.7 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF1513) Cytochrom_D1 PF02239.11 KLO15406.1 - 0.0049 15.2 0.0 0.37 9.0 0.0 2.3 2 0 0 2 2 2 2 Cytochrome D1 heme domain DUF1416 PF07210.7 KLO15406.1 - 0.11 12.0 0.0 0.19 11.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1416) PD40 PF07676.7 KLO15406.1 - 0.15 11.7 2.0 33 4.2 0.0 4.1 6 0 0 6 6 6 0 WD40-like Beta Propeller Repeat Zn_clus PF00172.13 KLO15407.1 - 0.0018 18.1 11.6 0.0023 17.8 8.1 1.1 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Dickkopf_N PF04706.7 KLO15407.1 - 2.2 8.4 11.2 2.4 8.4 0.9 2.1 1 1 1 2 2 2 0 Dickkopf N-terminal cysteine-rich region Fer4_4 PF12800.2 KLO15407.1 - 9.9 6.8 7.4 4.2 7.9 0.5 2.3 2 0 0 2 2 2 0 4Fe-4S binding domain TPT PF03151.11 KLO15410.1 - 6e-27 94.1 10.7 6e-27 94.1 7.4 2.8 2 1 0 2 2 2 1 Triose-phosphate Transporter family UAA PF08449.6 KLO15410.1 - 9.4e-10 37.8 21.5 1.5e-09 37.2 14.9 1.3 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.15 KLO15410.1 - 6.5e-06 26.1 27.7 0.00036 20.5 4.6 2.8 2 1 1 3 3 3 2 EamA-like transporter family Fungal_trans PF04082.13 KLO15411.1 - 7.1e-12 44.7 0.3 4.8e-11 42.0 0.0 2.1 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KLO15411.1 - 6.6e-05 22.7 14.0 0.00011 22.0 9.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain BTAD PF03704.12 KLO15411.1 - 0.085 13.1 0.0 0.18 12.0 0.0 1.5 1 0 0 1 1 1 0 Bacterial transcriptional activator domain APG5 PF04106.7 KLO15413.1 - 1.1e-46 158.7 0.0 1.5e-46 158.3 0.0 1.1 1 0 0 1 1 1 1 Autophagy protein Apg5 Dioxygenase_C PF00775.16 KLO15414.1 - 3.7e-53 179.4 0.0 5e-53 179.0 0.0 1.1 1 0 0 1 1 1 1 Dioxygenase Dioxygenase_N PF04444.9 KLO15414.1 - 7.8e-20 70.6 0.0 6.9e-19 67.6 0.0 2.1 2 0 0 2 2 2 1 Catechol dioxygenase N terminus CarboxypepD_reg PF13620.1 KLO15414.1 - 0.0021 18.0 0.1 0.014 15.4 0.0 2.3 2 1 0 2 2 2 1 Carboxypeptidase regulatory-like domain Peptidase_S8 PF00082.17 KLO15415.1 - 4.1e-51 173.7 1.8 5.8e-51 173.3 1.2 1.2 1 0 0 1 1 1 1 Subtilase family PA PF02225.17 KLO15415.1 - 5.7e-10 38.7 0.0 1.4e-09 37.5 0.0 1.7 1 0 0 1 1 1 1 PA domain DUF1034 PF06280.7 KLO15415.1 - 1.4e-08 35.1 0.1 3.5e-08 33.8 0.1 1.7 1 0 0 1 1 1 1 Fn3-like domain (DUF1034) Muskelin_N PF06588.6 KLO15416.1 - 2.9e-55 187.0 0.0 5.2e-55 186.2 0.0 1.3 1 0 0 1 1 1 1 Muskelin N-terminus Kelch_4 PF13418.1 KLO15416.1 - 3.5e-23 81.0 11.3 1.6e-06 27.7 0.2 6.2 6 1 1 7 7 7 4 Galactose oxidase, central domain Kelch_3 PF13415.1 KLO15416.1 - 1.8e-22 78.8 8.5 3.5e-09 36.5 0.0 7.6 8 1 0 8 8 8 3 Galactose oxidase, central domain Kelch_6 PF13964.1 KLO15416.1 - 2e-18 65.6 0.4 1.2e-05 25.3 0.0 6.4 7 0 0 7 7 7 2 Kelch motif Kelch_5 PF13854.1 KLO15416.1 - 2.8e-17 62.2 7.2 4.1e-06 26.6 0.0 5.7 5 0 0 5 5 5 4 Kelch motif Kelch_1 PF01344.20 KLO15416.1 - 7.3e-10 38.2 6.4 3.9e-06 26.3 0.1 4.1 4 0 0 4 4 4 2 Kelch motif F5_F8_type_C PF00754.20 KLO15416.1 - 9.7e-08 31.9 0.0 1.9e-07 30.9 0.0 1.5 1 0 0 1 1 1 1 F5/8 type C domain Kelch_2 PF07646.10 KLO15416.1 - 1.2e-07 31.1 1.4 0.00029 20.4 0.2 3.7 3 0 0 3 3 3 2 Kelch motif F-box-like PF12937.2 KLO15417.1 - 2.4e-05 23.9 1.2 0.00011 21.8 0.8 2.2 1 1 0 1 1 1 1 F-box-like FlaC_arch PF05377.6 KLO15417.1 - 0.1 12.5 0.1 0.32 10.9 0.1 1.8 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) F-box-like PF12937.2 KLO15418.1 - 3.5e-05 23.4 2.3 0.00011 21.8 0.9 2.4 2 1 0 2 2 2 1 F-box-like F-box-like_2 PF13013.1 KLO15418.1 - 0.078 12.6 0.1 0.18 11.5 0.1 1.6 1 0 0 1 1 1 0 F-box-like domain F-box PF00646.28 KLO15418.1 - 0.36 10.5 2.4 16 5.2 0.0 3.4 3 0 0 3 3 3 0 F-box domain MutS_III PF05192.13 KLO15419.1 - 0.0061 16.3 0.2 0.45 10.2 0.0 2.8 2 1 1 3 3 3 1 MutS domain III Tape_meas_lam_C PF09718.5 KLO15419.1 - 0.0095 15.8 0.0 0.82 9.6 0.0 3.5 2 1 1 3 3 3 1 Lambda phage tail tape-measure protein (Tape_meas_lam_C) Herpes_UL6 PF01763.11 KLO15419.1 - 0.015 13.5 0.3 0.022 12.9 0.2 1.2 1 0 0 1 1 1 0 Herpesvirus UL6 like DUF3510 PF12022.3 KLO15419.1 - 0.065 13.3 0.1 0.33 11.0 0.0 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF3510) DUF1657 PF07870.6 KLO15419.1 - 0.082 12.5 1.6 0.73 9.5 0.1 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1657) DUF3810 PF12725.2 KLO15419.1 - 0.16 10.8 0.4 0.62 8.9 0.1 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3810) Pex19 PF04614.7 KLO15419.1 - 0.23 11.0 9.6 0.027 14.1 2.4 2.4 2 1 1 3 3 3 0 Pex19 protein family ISG65-75 PF11727.3 KLO15419.1 - 0.91 8.5 11.2 0.11 11.4 0.5 2.8 1 1 1 2 2 2 0 Invariant surface glycoprotein Apolipoprotein PF01442.13 KLO15419.1 - 0.97 8.9 5.6 12 5.3 3.9 2.3 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain XH PF03469.9 KLO15419.1 - 1.3 8.6 8.0 0.63 9.7 0.1 2.9 1 1 2 3 3 3 0 XH domain DUF2959 PF11172.3 KLO15419.1 - 1.4 8.6 6.1 4.8 6.8 0.1 3.0 1 1 0 3 3 3 0 Protein of unknown function (DUF2959) DUF4600 PF15372.1 KLO15419.1 - 7.1 6.8 8.5 8.1 6.6 2.4 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4600) F-box-like PF12937.2 KLO15420.1 - 0.0018 17.9 0.6 0.0084 15.8 0.4 2.2 1 1 0 1 1 1 1 F-box-like F-box-like PF12937.2 KLO15421.1 - 5.2e-06 26.0 0.7 2e-05 24.1 0.2 2.3 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 KLO15421.1 - 0.012 15.2 0.4 1.9 8.2 0.4 3.0 2 0 0 2 2 2 0 F-box domain CHAD PF05235.9 KLO15421.1 - 0.11 12.0 0.0 0.63 9.5 0.0 1.9 2 0 0 2 2 2 0 CHAD domain LRR_4 PF12799.2 KLO15421.1 - 0.85 9.3 3.8 2.6 7.7 0.0 3.8 4 1 0 4 4 4 0 Leucine Rich repeats (2 copies) F-box-like PF12937.2 KLO15422.1 - 1.4e-05 24.7 0.3 5.4e-05 22.8 0.2 2.1 2 0 0 2 2 2 1 F-box-like RICH PF05062.7 KLO15422.1 - 0.33 11.1 2.2 14 5.8 0.0 2.9 3 0 0 3 3 3 0 RICH domain Arrestin_N PF00339.24 KLO15423.1 - 3.6e-12 46.3 0.0 7.2e-12 45.3 0.0 1.5 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.17 KLO15423.1 - 2.2e-06 27.8 0.0 0.0015 18.5 0.0 2.2 2 0 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain LDB19 PF13002.2 KLO15423.1 - 2.7e-05 23.7 0.0 3.7e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 Arrestin_N terminal like DSHCT PF08148.7 KLO15423.1 - 0.035 13.3 0.0 0.048 12.9 0.0 1.2 1 0 0 1 1 1 0 DSHCT (NUC185) domain Pyridoxal_deC PF00282.14 KLO15424.1 - 1.5e-17 63.1 0.0 3.4e-17 61.9 0.0 1.5 1 1 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.14 KLO15424.1 - 1.9e-09 36.7 0.0 8.6e-09 34.6 0.0 1.9 1 1 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.12 KLO15424.1 - 0.0023 17.0 0.2 0.0034 16.4 0.1 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Cys_Met_Meta_PP PF01053.15 KLO15424.1 - 0.13 10.5 0.0 0.2 9.9 0.0 1.2 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme Prefoldin_2 PF01920.15 KLO15425.1 - 1.1e-20 73.4 1.1 1.4e-20 72.9 0.7 1.2 1 0 0 1 1 1 1 Prefoldin subunit DUF465 PF04325.8 KLO15425.1 - 0.0048 16.5 6.8 0.032 13.9 0.1 2.6 3 0 0 3 3 3 1 Protein of unknown function (DUF465) DivIC PF04977.10 KLO15425.1 - 0.016 14.6 3.4 1.4 8.4 0.4 2.4 2 1 0 2 2 2 0 Septum formation initiator PEP-utilisers_N PF05524.8 KLO15425.1 - 0.018 14.8 0.5 0.036 13.8 0.1 1.6 2 0 0 2 2 2 0 PEP-utilising enzyme, N-terminal DASH_Dam1 PF08653.5 KLO15425.1 - 0.059 13.1 0.6 1.6 8.5 0.0 2.4 2 0 0 2 2 2 0 DASH complex subunit Dam1 DUF4140 PF13600.1 KLO15425.1 - 0.066 13.6 4.3 0.53 10.7 0.7 2.1 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) TBPIP PF07106.8 KLO15425.1 - 0.077 12.5 4.9 0.49 9.9 0.1 2.1 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Prefoldin PF02996.12 KLO15425.1 - 0.088 12.4 3.7 6 6.5 2.6 2.2 1 1 0 1 1 1 0 Prefoldin subunit Seryl_tRNA_N PF02403.17 KLO15425.1 - 0.19 11.7 4.1 5.7 7.0 0.3 2.2 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain GAS PF13851.1 KLO15425.1 - 0.21 10.7 8.9 2.9 7.0 5.6 2.0 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding Sipho_Gp157 PF05565.6 KLO15425.1 - 0.25 10.9 5.8 1.3 8.5 0.2 2.1 2 0 0 2 2 2 0 Siphovirus Gp157 HalX PF08663.5 KLO15425.1 - 0.29 11.1 5.4 7.7 6.5 0.2 2.6 2 1 0 2 2 2 0 HalX domain BLOC1_2 PF10046.4 KLO15425.1 - 0.4 10.8 3.1 15 5.7 0.0 2.2 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 TMF_DNA_bd PF12329.3 KLO15425.1 - 0.59 9.9 8.8 2.1 8.2 0.2 2.5 2 1 1 3 3 3 0 TATA element modulatory factor 1 DNA binding Gp-FAR-1 PF05823.7 KLO15425.1 - 1 9.3 4.7 2.4 8.0 0.6 2.0 2 0 0 2 2 2 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) DUF904 PF06005.7 KLO15425.1 - 1.5 9.1 6.3 1.2 9.5 2.5 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF904) NYD-SP28 PF14772.1 KLO15425.1 - 3.5 7.7 8.1 7.1 6.7 1.4 2.1 2 0 0 2 2 2 0 Sperm tail TPR_MLP1_2 PF07926.7 KLO15425.1 - 8.7 6.1 9.8 3.6 7.3 2.5 2.3 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein COesterase PF00135.23 KLO15426.1 - 9.1e-92 308.4 0.0 1e-91 308.2 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 KLO15426.1 - 7.5e-08 32.2 0.1 3.5e-07 30.0 0.1 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Erf4 PF10256.4 KLO15427.1 - 0.00084 19.1 0.0 0.0013 18.5 0.0 1.4 1 0 0 1 1 1 1 Golgin subfamily A member 7/ERF4 family peroxidase PF00141.18 KLO15428.1 - 1.7e-47 161.8 0.0 2.9e-47 161.1 0.0 1.3 1 0 0 1 1 1 1 Peroxidase FAD_binding_3 PF01494.14 KLO15429.1 - 1.8e-66 224.6 0.0 2.4e-66 224.2 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 KLO15429.1 - 5.8e-05 22.1 0.0 0.013 14.4 0.0 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase Thi4 PF01946.12 KLO15429.1 - 0.00069 18.7 0.0 0.0013 17.8 0.0 1.4 1 0 0 1 1 1 1 Thi4 family Pyr_redox_3 PF13738.1 KLO15429.1 - 0.0072 16.4 0.0 0.014 15.5 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 KLO15429.1 - 0.0097 16.2 0.3 0.14 12.5 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 KLO15429.1 - 0.02 14.8 0.0 0.035 13.9 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 KLO15429.1 - 0.027 12.9 0.0 0.048 12.1 0.0 1.4 1 0 0 1 1 1 0 HI0933-like protein NAD_binding_8 PF13450.1 KLO15429.1 - 0.031 14.3 0.0 0.077 13.0 0.0 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.9 KLO15429.1 - 0.033 12.8 0.0 0.05 12.2 0.0 1.2 1 0 0 1 1 1 0 Tryptophan halogenase NAD_binding_7 PF13241.1 KLO15429.1 - 0.043 14.0 0.0 0.12 12.5 0.0 1.7 1 0 0 1 1 1 0 Putative NAD(P)-binding NAD_binding_9 PF13454.1 KLO15429.1 - 0.048 13.4 0.1 0.1 12.3 0.0 1.5 1 0 0 1 1 1 0 FAD-NAD(P)-binding TrkA_N PF02254.13 KLO15429.1 - 0.049 13.6 0.0 0.12 12.3 0.0 1.7 1 0 0 1 1 1 0 TrkA-N domain F-box-like PF12937.2 KLO15430.1 - 2.5e-06 27.1 0.1 5.8e-06 25.9 0.1 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KLO15430.1 - 0.00097 18.7 0.3 0.007 16.0 0.2 2.3 1 1 0 1 1 1 1 F-box domain F-box-like_2 PF13013.1 KLO15430.1 - 0.033 13.9 0.0 0.11 12.2 0.0 1.8 1 1 1 2 2 2 0 F-box-like domain F-box-like PF12937.2 KLO15432.1 - 0.028 14.1 0.0 0.092 12.4 0.0 1.9 1 0 0 1 1 1 0 F-box-like F-box-like PF12937.2 KLO15433.1 - 0.0014 18.2 0.2 0.0068 16.1 0.0 2.2 2 1 1 3 3 3 1 F-box-like PepSY_TM_2 PF13703.1 KLO15434.1 - 0.15 12.2 0.2 0.15 12.2 0.1 1.9 2 0 0 2 2 2 0 PepSY-associated TM helix DUF3352 PF11832.3 KLO15434.1 - 0.17 10.1 0.3 0.24 9.6 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3352) F-box-like PF12937.2 KLO15436.1 - 0.041 13.6 0.1 0.11 12.2 0.1 1.7 1 0 0 1 1 1 0 F-box-like DMA PF03474.9 KLO15437.1 - 6.8e-05 22.6 0.0 0.0028 17.4 0.0 2.6 2 0 0 2 2 2 1 DMRTA motif F-box-like PF12937.2 KLO15437.1 - 0.019 14.6 0.1 0.07 12.8 0.0 2.0 1 0 0 1 1 1 0 F-box-like LRR_6 PF13516.1 KLO15437.1 - 0.45 10.7 3.3 1 9.6 0.2 3.0 2 0 0 2 2 2 0 Leucine Rich repeat F-box-like PF12937.2 KLO15438.1 - 0.025 14.2 0.1 0.22 11.2 0.0 2.6 2 0 0 2 2 2 0 F-box-like IncA PF04156.9 KLO15438.1 - 0.53 9.8 3.3 0.93 9.0 2.3 1.4 1 0 0 1 1 1 0 IncA protein F-box-like PF12937.2 KLO15439.1 - 0.023 14.4 0.3 0.023 14.4 0.2 2.1 2 0 0 2 2 2 0 F-box-like F-box PF00646.28 KLO15439.1 - 0.039 13.6 0.8 0.34 10.6 0.1 2.8 2 0 0 2 2 2 0 F-box domain Far-17a_AIG1 PF04750.9 KLO15439.1 - 0.13 11.4 0.0 0.21 10.7 0.0 1.3 1 0 0 1 1 1 0 FAR-17a/AIG1-like protein F-box-like PF12937.2 KLO15440.1 - 0.0031 17.1 2.3 0.13 11.9 0.1 2.9 2 0 0 2 2 2 1 F-box-like DMA PF03474.9 KLO15440.1 - 0.038 13.8 0.0 0.33 10.8 0.0 2.5 2 0 0 2 2 2 0 DMRTA motif NUFIP2 PF15293.1 KLO15440.1 - 0.23 10.1 0.2 0.32 9.6 0.2 1.1 1 0 0 1 1 1 0 Nuclear fragile X mental retardation-interacting protein 2 F-box PF00646.28 KLO15440.1 - 0.37 10.5 7.7 5.8 6.7 1.7 3.6 3 0 0 3 3 3 0 F-box domain F-box-like PF12937.2 KLO15441.1 - 0.0029 17.2 0.2 0.011 15.4 0.0 2.1 2 0 0 2 2 2 1 F-box-like Dehydratase_LU PF02286.10 KLO15441.1 - 0.12 10.5 0.0 0.24 9.5 0.0 1.4 1 0 0 1 1 1 0 Dehydratase large subunit F-box PF00646.28 KLO15441.1 - 0.39 10.4 3.4 1.1 8.9 0.0 3.0 3 0 0 3 3 3 0 F-box domain F-box-like PF12937.2 KLO15442.1 - 0.012 15.3 0.0 0.038 13.7 0.0 2.0 1 0 0 1 1 1 0 F-box-like F-box-like PF12937.2 KLO15443.1 - 0.0033 17.0 0.0 0.01 15.5 0.0 1.9 1 0 0 1 1 1 1 F-box-like ABC_tran PF00005.22 KLO15446.1 - 2.3e-41 141.2 0.0 3.1e-19 69.6 0.0 3.8 2 2 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 KLO15446.1 - 1.4e-15 58.0 1.1 0.011 15.6 0.0 4.5 3 2 1 4 4 4 4 AAA domain SMC_N PF02463.14 KLO15446.1 - 3.1e-13 49.4 0.5 0.0012 18.1 0.0 4.1 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 KLO15446.1 - 8.8e-09 34.7 0.3 0.0032 16.9 0.1 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain HEAT_2 PF13646.1 KLO15446.1 - 4.3e-07 30.1 9.0 0.0022 18.2 0.0 3.4 2 1 1 3 3 2 2 HEAT repeats AAA_17 PF13207.1 KLO15446.1 - 1.9e-06 28.6 0.0 0.013 16.3 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.1 KLO15446.1 - 3.8e-06 27.0 0.0 0.024 14.7 0.0 2.8 2 0 0 2 2 2 2 AAA domain Miro PF08477.8 KLO15446.1 - 6.7e-06 26.5 0.0 0.055 13.9 0.0 2.7 2 0 0 2 2 2 2 Miro-like protein DUF87 PF01935.12 KLO15446.1 - 1.3e-05 25.1 0.2 0.0057 16.4 0.0 3.0 3 0 0 3 3 2 1 Domain of unknown function DUF87 AAA_10 PF12846.2 KLO15446.1 - 1.4e-05 24.6 0.2 0.023 14.1 0.1 3.1 4 0 0 4 4 3 2 AAA-like domain SbcCD_C PF13558.1 KLO15446.1 - 2e-05 24.3 0.4 0.14 12.0 0.0 3.6 3 1 0 3 3 2 2 Putative exonuclease SbcCD, C subunit MMR_HSR1 PF01926.18 KLO15446.1 - 2.1e-05 24.4 0.0 0.14 12.1 0.0 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_18 PF13238.1 KLO15446.1 - 4.9e-05 23.6 0.2 0.02 15.2 0.1 2.7 2 0 0 2 2 2 1 AAA domain NACHT PF05729.7 KLO15446.1 - 5.6e-05 22.8 0.1 0.25 10.9 0.1 2.6 2 0 0 2 2 2 2 NACHT domain DUF258 PF03193.11 KLO15446.1 - 5.9e-05 22.3 0.1 0.07 12.3 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 Chromo PF00385.19 KLO15446.1 - 8.2e-05 22.2 0.3 0.0002 20.9 0.2 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain AAA_15 PF13175.1 KLO15446.1 - 0.00013 21.1 0.1 1.1 8.1 0.0 3.6 3 1 1 4 4 4 1 AAA ATPase domain MobB PF03205.9 KLO15446.1 - 0.00025 20.7 0.8 0.3 10.7 0.0 3.2 4 0 0 4 4 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_16 PF13191.1 KLO15446.1 - 0.0003 20.8 0.8 0.059 13.3 0.0 3.5 3 0 0 3 3 3 1 AAA ATPase domain AAA_23 PF13476.1 KLO15446.1 - 0.00039 20.8 6.8 0.085 13.1 0.0 3.1 4 0 0 4 4 3 2 AAA domain RNA_helicase PF00910.17 KLO15446.1 - 0.00039 20.5 0.0 1.5 9.0 0.0 3.1 2 0 0 2 2 2 2 RNA helicase AAA_33 PF13671.1 KLO15446.1 - 0.00047 20.0 0.0 0.39 10.5 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.1 KLO15446.1 - 0.00057 19.8 0.0 0.57 10.1 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA PF00004.24 KLO15446.1 - 0.00085 19.5 0.0 3.5 7.8 0.0 3.4 4 0 0 4 4 2 2 ATPase family associated with various cellular activities (AAA) ArgK PF03308.11 KLO15446.1 - 0.0015 17.3 0.7 0.43 9.3 0.1 2.5 2 0 0 2 2 2 1 ArgK protein AAA_25 PF13481.1 KLO15446.1 - 0.0016 17.8 0.0 2.1 7.7 0.0 3.0 3 0 0 3 3 2 1 AAA domain AAA_30 PF13604.1 KLO15446.1 - 0.0023 17.5 0.4 2.9 7.4 0.0 2.8 2 0 0 2 2 2 2 AAA domain Arch_ATPase PF01637.13 KLO15446.1 - 0.0033 17.1 0.1 5.7 6.5 0.0 3.4 3 0 0 3 3 3 0 Archaeal ATPase AAA_13 PF13166.1 KLO15446.1 - 0.0042 15.6 0.0 1.5 7.2 0.0 2.6 2 0 0 2 2 2 1 AAA domain FtsK_SpoIIIE PF01580.13 KLO15446.1 - 0.0053 16.2 0.1 0.98 8.8 0.0 2.6 2 0 0 2 2 2 1 FtsK/SpoIIIE family HEAT_EZ PF13513.1 KLO15446.1 - 0.013 15.9 7.4 17 6.0 1.0 4.8 3 2 1 4 4 4 0 HEAT-like repeat DUF815 PF05673.8 KLO15446.1 - 0.02 13.8 0.3 3.3 6.5 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF815) NB-ARC PF00931.17 KLO15446.1 - 0.036 12.9 0.4 3.5 6.4 0.1 2.3 2 0 0 2 2 2 0 NB-ARC domain HEAT PF02985.17 KLO15446.1 - 0.043 13.8 10.7 0.11 12.5 0.1 4.5 5 0 0 5 5 3 0 HEAT repeat Dynamin_N PF00350.18 KLO15446.1 - 0.05 13.4 0.0 1.4 8.6 0.0 2.6 2 0 0 2 2 2 0 Dynamin family AAA_14 PF13173.1 KLO15446.1 - 0.061 13.2 0.0 7.9 6.3 0.0 2.8 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.1 KLO15446.1 - 0.07 12.8 1.3 2.5 7.8 0.1 3.5 4 0 0 4 4 4 0 Part of AAA domain AAA_5 PF07728.9 KLO15446.1 - 0.71 9.5 4.6 13 5.5 0.1 3.7 4 0 0 4 4 3 0 AAA domain (dynein-related subfamily) U3snoRNP10 PF12397.3 KLO15446.1 - 1.1 9.2 5.1 0.71 9.8 1.2 2.4 2 1 0 2 2 2 0 U3 small nucleolar RNA-associated protein 10 V_ATPase_I PF01496.14 KLO15447.1 - 2.5e-275 915.1 0.0 2.8e-275 915.0 0.0 1.0 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family Clusterin PF01093.12 KLO15447.1 - 0.17 10.6 0.0 0.26 10.0 0.0 1.2 1 0 0 1 1 1 0 Clusterin SlyX PF04102.7 KLO15447.1 - 0.17 12.2 0.7 0.65 10.4 0.1 2.2 3 0 0 3 3 3 0 SlyX F-box-like PF12937.2 KLO15448.1 - 4.1e-05 23.2 5.1 4.7e-05 23.0 1.4 2.6 2 0 0 2 2 2 1 F-box-like LRR_4 PF12799.2 KLO15448.1 - 0.97 9.1 8.6 5.5 6.7 0.0 3.9 4 1 0 5 5 5 0 Leucine Rich repeats (2 copies) LRR_7 PF13504.1 KLO15448.1 - 1.8 9.1 4.6 18 6.0 0.0 4.3 5 0 0 5 5 5 0 Leucine rich repeat Acyl-CoA_dh_M PF02770.14 KLO15450.1 - 0.0006 19.2 0.0 0.0011 18.3 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_M PF02770.14 KLO15452.1 - 0.00074 18.9 0.0 0.0014 18.0 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.19 KLO15452.1 - 0.0035 17.4 0.2 0.0059 16.7 0.1 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain F-box-like PF12937.2 KLO15453.1 - 0.065 12.9 0.4 0.31 10.8 0.1 2.2 2 0 0 2 2 2 0 F-box-like Vps16_N PF04841.8 KLO15454.1 - 0.11 11.0 0.0 0.12 10.8 0.0 1.0 1 0 0 1 1 1 0 Vps16, N-terminal region Acyl-CoA_dh_M PF02770.14 KLO15455.1 - 0.0078 15.6 0.0 0.015 14.7 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain RhoGEF PF00621.15 KLO15456.1 - 4.1e-45 153.8 2.1 2.1e-44 151.5 1.2 2.1 2 0 0 2 2 2 1 RhoGEF domain SH3_9 PF14604.1 KLO15456.1 - 9.1e-19 66.7 1.1 6e-09 35.3 0.2 2.5 2 0 0 2 2 2 2 Variant SH3 domain SH3_1 PF00018.23 KLO15456.1 - 9.5e-19 66.5 0.1 5e-10 38.6 0.0 2.6 2 0 0 2 2 2 2 SH3 domain EF-hand_4 PF12763.2 KLO15456.1 - 8.2e-17 60.8 0.0 2.2e-16 59.4 0.0 1.6 1 0 0 1 1 1 1 Cytoskeletal-regulatory complex EF hand SH3_2 PF07653.12 KLO15456.1 - 3.3e-09 36.0 0.0 0.00028 20.3 0.0 2.5 2 0 0 2 2 2 2 Variant SH3 domain WH2 PF02205.15 KLO15456.1 - 8.9e-09 34.6 0.0 2.2e-08 33.4 0.0 1.7 1 0 0 1 1 1 1 WH2 motif PH PF00169.24 KLO15456.1 - 2e-06 27.9 0.0 7.1e-06 26.1 0.0 2.0 2 0 0 2 2 2 1 PH domain EF-hand_1 PF00036.27 KLO15456.1 - 1.8e-05 23.7 0.0 0.028 13.6 0.0 3.1 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.1 KLO15456.1 - 4e-05 23.1 0.0 0.0067 16.0 0.0 2.4 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.1 KLO15456.1 - 0.0054 16.5 0.1 4.6 7.4 0.0 2.9 2 0 0 2 2 2 1 EF-hand domain Borrelia_lipo_2 PF06238.6 KLO15456.1 - 0.2 11.7 0.9 0.42 10.6 0.6 1.4 1 0 0 1 1 1 0 Borrelia burgdorferi BBR25 lipoprotein Mononeg_RNA_pol PF00946.14 KLO15456.1 - 0.21 8.9 0.0 0.32 8.3 0.0 1.2 1 0 0 1 1 1 0 Mononegavirales RNA dependent RNA polymerase F-box-like PF12937.2 KLO15459.1 - 3.9e-06 26.4 1.1 1.2e-05 24.9 0.8 1.9 1 0 0 1 1 1 1 F-box-like DUF2101 PF09874.4 KLO15460.1 - 0.05 13.0 0.7 5.2 6.5 0.0 2.2 2 0 0 2 2 2 0 Predicted membrane protein (DUF2101) DUF1106 PF06523.6 KLO15460.1 - 0.059 13.2 0.1 0.14 12.0 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1106) F-box-like PF12937.2 KLO15463.1 - 2.9e-06 26.9 2.2 7.7e-06 25.5 1.0 2.3 2 0 0 2 2 2 1 F-box-like NACHT PF05729.7 KLO15466.1 - 3.9e-17 62.4 0.0 3e-08 33.5 0.0 4.4 2 2 0 2 2 2 2 NACHT domain AAA_16 PF13191.1 KLO15466.1 - 2e-10 40.9 0.0 3.1e-05 24.0 0.0 3.2 2 1 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.1 KLO15466.1 - 1.2e-09 38.4 0.0 0.001 19.2 0.0 3.0 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.1 KLO15466.1 - 2.1e-07 30.6 0.0 0.0034 17.0 0.0 2.9 2 0 0 2 2 2 2 Part of AAA domain NB-ARC PF00931.17 KLO15466.1 - 2.3e-07 29.9 0.0 0.0026 16.6 0.0 2.6 2 1 0 2 2 2 2 NB-ARC domain AAA PF00004.24 KLO15466.1 - 1.4e-06 28.5 0.0 0.0087 16.2 0.0 3.0 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.17 KLO15466.1 - 4.1e-06 26.9 0.0 0.019 15.1 0.0 2.9 3 0 0 3 3 2 2 RNA helicase AAA_17 PF13207.1 KLO15466.1 - 2.6e-05 25.0 0.1 0.05 14.4 0.0 3.5 3 0 0 3 3 2 1 AAA domain AAA_18 PF13238.1 KLO15466.1 - 3.7e-05 24.0 0.0 0.029 14.6 0.0 3.3 3 0 0 3 3 2 1 AAA domain AAA_25 PF13481.1 KLO15466.1 - 3.8e-05 23.1 0.0 0.061 12.7 0.0 3.1 3 0 0 3 3 3 1 AAA domain DUF2075 PF09848.4 KLO15466.1 - 4.2e-05 22.6 0.0 0.083 11.8 0.0 2.5 3 0 0 3 3 2 2 Uncharacterized conserved protein (DUF2075) AAA_33 PF13671.1 KLO15466.1 - 0.00017 21.4 0.0 0.46 10.3 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_11 PF13086.1 KLO15466.1 - 0.00036 20.1 0.0 0.21 11.1 0.0 2.6 2 0 0 2 2 2 1 AAA domain KaiC PF06745.8 KLO15466.1 - 0.0006 18.9 0.0 0.49 9.4 0.0 2.5 2 0 0 2 2 2 2 KaiC KAP_NTPase PF07693.9 KLO15466.1 - 0.00063 18.8 0.1 1.3 7.9 0.0 4.0 4 0 0 4 4 4 1 KAP family P-loop domain Zeta_toxin PF06414.7 KLO15466.1 - 0.0009 18.3 0.0 0.23 10.5 0.0 2.7 2 0 0 2 2 2 1 Zeta toxin APS_kinase PF01583.15 KLO15466.1 - 0.00095 18.8 0.0 0.57 9.8 0.0 2.6 2 0 0 2 2 2 1 Adenylylsulphate kinase Parvo_NS1 PF01057.12 KLO15466.1 - 0.0016 17.4 0.1 0.52 9.1 0.0 2.3 2 0 0 2 2 2 1 Parvovirus non-structural protein NS1 AAA_5 PF07728.9 KLO15466.1 - 0.0016 18.1 0.0 0.43 10.2 0.0 2.7 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) Torsin PF06309.6 KLO15466.1 - 0.0031 17.3 0.0 0.023 14.6 0.0 2.2 2 0 0 2 2 2 1 Torsin cobW PF02492.14 KLO15466.1 - 0.0037 16.7 0.0 0.41 10.0 0.0 2.4 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain NTPase_1 PF03266.10 KLO15466.1 - 0.0058 16.3 0.1 1 9.0 0.0 2.5 2 0 0 2 2 2 1 NTPase Viral_helicase1 PF01443.13 KLO15466.1 - 0.006 16.1 0.0 0.31 10.5 0.0 2.4 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase Sigma54_activat PF00158.21 KLO15466.1 - 0.0062 16.0 0.0 0.81 9.1 0.0 2.4 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_28 PF13521.1 KLO15466.1 - 0.012 15.5 0.0 1.4 8.8 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.1 KLO15466.1 - 0.02 14.4 0.0 1.2 8.6 0.0 2.3 2 0 0 2 2 2 0 AAA domain KTI12 PF08433.5 KLO15466.1 - 0.027 13.6 0.0 2.9 7.0 0.0 2.4 2 0 0 2 2 2 0 Chromatin associated protein KTI12 ABC_tran PF00005.22 KLO15466.1 - 0.047 13.9 0.0 5.7 7.2 0.0 2.9 2 0 0 2 2 2 0 ABC transporter Arch_ATPase PF01637.13 KLO15466.1 - 0.049 13.3 0.0 7.5 6.1 0.0 2.5 2 0 0 2 2 2 0 Archaeal ATPase AAA_14 PF13173.1 KLO15466.1 - 0.052 13.4 0.0 16 5.4 0.0 2.9 2 0 0 2 2 2 0 AAA domain RuvB_N PF05496.7 KLO15466.1 - 0.056 12.4 0.0 2 7.4 0.0 2.3 2 0 0 2 2 2 0 Holliday junction DNA helicase ruvB N-terminus DnaB_C PF03796.10 KLO15466.1 - 0.061 12.1 0.0 4.1 6.2 0.0 2.7 3 0 0 3 3 2 0 DnaB-like helicase C terminal domain UPF0079 PF02367.12 KLO15466.1 - 0.064 12.8 0.0 13 5.4 0.0 2.5 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 AAA_10 PF12846.2 KLO15466.1 - 0.065 12.6 0.0 6.6 6.0 0.0 2.7 2 0 0 2 2 2 0 AAA-like domain FtsK_SpoIIIE PF01580.13 KLO15466.1 - 0.065 12.6 0.0 13 5.1 0.0 2.5 2 0 0 2 2 2 0 FtsK/SpoIIIE family Miro PF08477.8 KLO15466.1 - 0.14 12.6 0.0 4.7 7.7 0.0 2.7 2 0 0 2 2 2 0 Miro-like protein TIP49 PF06068.8 KLO15466.1 - 0.16 10.6 0.0 4.4 5.9 0.0 2.1 2 0 0 2 2 2 0 TIP49 C-terminus PIF1 PF05970.9 KLO15466.1 - 0.17 10.7 0.0 3.6 6.4 0.0 2.5 3 0 0 3 3 3 0 PIF1-like helicase AAA_24 PF13479.1 KLO15466.1 - 0.2 11.1 0.0 2.3 7.7 0.0 2.3 2 0 0 2 2 2 0 AAA domain ArgK PF03308.11 KLO15466.1 - 0.35 9.6 0.0 25 3.5 0.0 2.3 2 0 0 2 2 2 0 ArgK protein HPHLAWLY PF14925.1 KLO15468.1 - 4.9 5.0 18.4 2 6.2 5.4 2.0 1 1 1 2 2 2 0 Domain of unknown function Methyltransf_7 PF03492.10 KLO15475.1 - 0.056 12.2 0.0 0.069 11.8 0.0 1.2 1 0 0 1 1 1 0 SAM dependent carboxyl methyltransferase F-box-like PF12937.2 KLO15477.1 - 8.3e-08 31.8 1.8 3e-07 30.0 0.4 2.4 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 KLO15477.1 - 0.15 11.7 6.9 0.41 10.3 0.9 3.6 3 1 0 3 3 3 0 F-box domain F-box-like PF12937.2 KLO15478.1 - 2.2e-10 40.0 0.4 6.9e-10 38.4 0.2 2.0 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KLO15478.1 - 4.3e-07 29.4 0.6 4.3e-07 29.4 0.4 2.9 3 0 0 3 3 3 1 F-box domain Cytomega_UL20A PF05984.7 KLO15479.1 - 0.18 12.0 1.5 0.35 11.1 0.4 1.8 2 0 0 2 2 2 0 Cytomegalovirus UL20A protein NACHT PF05729.7 KLO15480.1 - 1.3e-18 67.2 1.1 2.5e-09 36.9 0.0 4.3 2 2 0 2 2 2 2 NACHT domain AAA_16 PF13191.1 KLO15480.1 - 7.9e-15 55.3 0.1 5.9e-07 29.6 0.0 2.7 2 0 0 2 2 2 2 AAA ATPase domain Pkinase_Tyr PF07714.12 KLO15480.1 - 5.1e-11 42.1 0.0 1e-09 37.8 0.0 2.5 2 0 0 2 2 2 1 Protein tyrosine kinase NB-ARC PF00931.17 KLO15480.1 - 3e-10 39.4 0.0 2.7e-05 23.1 0.0 2.7 2 0 0 2 2 2 2 NB-ARC domain Pkinase PF00069.20 KLO15480.1 - 1.4e-09 37.5 0.0 2.7e-09 36.5 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain AAA_22 PF13401.1 KLO15480.1 - 4.8e-07 29.9 0.0 0.024 14.7 0.0 3.2 2 1 0 2 2 2 2 AAA domain AAA PF00004.24 KLO15480.1 - 3.2e-05 24.1 0.0 1 9.5 0.0 4.0 2 1 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) APS_kinase PF01583.15 KLO15480.1 - 4.7e-05 23.1 0.0 0.18 11.4 0.0 2.6 2 0 0 2 2 2 2 Adenylylsulphate kinase Arch_ATPase PF01637.13 KLO15480.1 - 7.9e-05 22.4 0.0 0.0021 17.8 0.0 2.7 2 1 0 2 2 2 1 Archaeal ATPase AAA_17 PF13207.1 KLO15480.1 - 0.00016 22.4 0.1 0.6 10.9 0.0 3.8 3 0 0 3 3 2 1 AAA domain RNA_helicase PF00910.17 KLO15480.1 - 0.00048 20.2 0.0 1.2 9.3 0.0 2.7 2 0 0 2 2 2 2 RNA helicase KAP_NTPase PF07693.9 KLO15480.1 - 0.00052 19.1 0.7 0.88 8.5 0.1 3.9 4 0 0 4 4 4 1 KAP family P-loop domain DUF2075 PF09848.4 KLO15480.1 - 0.00073 18.6 0.0 0.34 9.8 0.0 2.5 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2075) Zeta_toxin PF06414.7 KLO15480.1 - 0.00076 18.6 0.0 0.025 13.6 0.0 2.4 2 0 0 2 2 2 1 Zeta toxin AAA_18 PF13238.1 KLO15480.1 - 0.0015 18.7 0.0 2 8.7 0.0 3.0 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.1 KLO15480.1 - 0.0041 17.0 0.0 2.5 7.9 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 KLO15480.1 - 0.0062 16.2 0.0 1.7 8.4 0.0 2.9 2 0 0 2 2 2 1 Part of AAA domain Parvo_NS1 PF01057.12 KLO15480.1 - 0.0072 15.2 0.0 1.2 7.9 0.0 2.3 2 0 0 2 2 2 1 Parvovirus non-structural protein NS1 AAA_30 PF13604.1 KLO15480.1 - 0.018 14.5 0.0 1.1 8.7 0.0 2.5 2 0 0 2 2 2 0 AAA domain Sigma54_activat PF00158.21 KLO15480.1 - 0.018 14.4 0.0 1.7 8.1 0.0 2.3 2 0 0 2 2 2 0 Sigma-54 interaction domain Torsin PF06309.6 KLO15480.1 - 0.03 14.2 0.0 19 5.1 0.0 3.4 4 0 0 4 4 2 0 Torsin PIF1 PF05970.9 KLO15480.1 - 0.037 12.9 0.0 0.18 10.7 0.0 2.0 2 0 0 2 2 2 0 PIF1-like helicase AAA_25 PF13481.1 KLO15480.1 - 0.044 13.1 0.0 8.1 5.7 0.0 2.9 3 0 0 3 3 3 0 AAA domain Viral_helicase1 PF01443.13 KLO15480.1 - 0.079 12.4 0.0 2.2 7.7 0.0 2.4 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase ArgK PF03308.11 KLO15480.1 - 0.1 11.3 0.0 3.2 6.4 0.0 2.5 2 0 0 2 2 2 0 ArgK protein NTPase_1 PF03266.10 KLO15480.1 - 0.12 12.1 0.0 19 4.9 0.0 2.5 2 0 0 2 2 2 0 NTPase ABC_tran PF00005.22 KLO15480.1 - 0.15 12.3 0.0 54 4.0 0.0 3.2 4 0 0 4 4 3 0 ABC transporter TIP49 PF06068.8 KLO15480.1 - 0.17 10.5 0.0 6.6 5.3 0.0 2.2 2 0 0 2 2 2 0 TIP49 C-terminus Pkinase_Tyr PF07714.12 KLO15481.1 - 2.7e-12 46.3 0.0 3.6e-12 45.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 KLO15481.1 - 4.8e-09 35.7 0.0 5.4e-09 35.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain NACHT PF05729.7 KLO15485.1 - 1.3e-08 34.6 0.5 2e-06 27.5 0.2 3.3 2 1 0 2 2 2 1 NACHT domain NB-ARC PF00931.17 KLO15485.1 - 4.1e-06 25.8 0.0 9.5e-06 24.6 0.0 1.6 1 0 0 1 1 1 1 NB-ARC domain AAA_16 PF13191.1 KLO15485.1 - 2.8e-05 24.1 0.0 7.6e-05 22.7 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 KLO15485.1 - 0.00024 21.2 0.0 0.0012 18.9 0.0 2.3 2 1 0 2 2 2 1 AAA domain AAA PF00004.24 KLO15485.1 - 0.00061 20.0 0.0 0.036 14.2 0.0 3.2 1 1 1 2 2 2 1 ATPase family associated with various cellular activities (AAA) Zeta_toxin PF06414.7 KLO15485.1 - 0.0011 18.0 0.0 0.0021 17.1 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin KAP_NTPase PF07693.9 KLO15485.1 - 0.019 13.9 0.2 0.34 9.8 0.0 2.3 2 0 0 2 2 2 0 KAP family P-loop domain AAA_17 PF13207.1 KLO15485.1 - 0.027 15.2 0.1 0.14 12.9 0.1 2.5 1 1 0 1 1 1 0 AAA domain DUF2075 PF09848.4 KLO15485.1 - 0.033 13.1 0.0 0.057 12.3 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_18 PF13238.1 KLO15485.1 - 0.055 13.7 0.2 1.2 9.4 0.0 2.9 3 1 1 4 4 4 0 AAA domain APS_kinase PF01583.15 KLO15485.1 - 0.059 13.0 0.0 0.27 10.8 0.0 2.1 2 0 0 2 2 2 0 Adenylylsulphate kinase AAA_19 PF13245.1 KLO15485.1 - 0.13 12.0 0.0 0.64 9.8 0.0 2.1 2 0 0 2 2 2 0 Part of AAA domain Torsin PF06309.6 KLO15485.1 - 0.16 11.9 0.0 0.85 9.5 0.0 2.1 2 0 0 2 2 2 0 Torsin Pkinase_Tyr PF07714.12 KLO15486.1 - 1.8e-22 79.6 0.0 2.5e-22 79.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 KLO15486.1 - 2.4e-18 66.2 0.0 3e-18 65.9 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.1 KLO15486.1 - 0.00044 19.3 0.0 0.00058 18.8 0.0 1.1 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.17 KLO15486.1 - 0.0017 17.7 0.0 0.0026 17.1 0.0 1.2 1 0 0 1 1 1 1 RIO1 family HisKA_2 PF07568.7 KLO15490.1 - 0.049 13.4 0.0 0.16 11.8 0.0 2.0 1 1 0 1 1 1 0 Histidine kinase Dak2 PF02734.12 KLO15490.1 - 0.14 11.8 0.4 0.58 9.8 0.0 1.9 2 0 0 2 2 2 0 DAK2 domain NACHT PF05729.7 KLO15491.1 - 6e-07 29.2 0.4 1.5e-05 24.7 0.3 2.3 1 1 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 KLO15491.1 - 1.2e-06 28.6 0.0 3.2e-06 27.2 0.0 1.7 2 0 0 2 2 2 1 AAA ATPase domain NB-ARC PF00931.17 KLO15491.1 - 1.1e-05 24.4 0.1 0.00013 20.9 0.0 2.1 2 0 0 2 2 2 1 NB-ARC domain AAA PF00004.24 KLO15491.1 - 9.8e-05 22.5 0.1 0.0016 18.6 0.0 2.5 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) APS_kinase PF01583.15 KLO15491.1 - 0.00076 19.1 0.0 0.0038 16.8 0.0 1.9 2 0 0 2 2 2 1 Adenylylsulphate kinase KAP_NTPase PF07693.9 KLO15491.1 - 0.0016 17.4 0.0 0.35 9.8 0.0 2.3 2 0 0 2 2 2 2 KAP family P-loop domain Zeta_toxin PF06414.7 KLO15491.1 - 0.0016 17.5 0.0 0.0029 16.7 0.0 1.3 1 0 0 1 1 1 1 Zeta toxin AAA_18 PF13238.1 KLO15491.1 - 0.0045 17.2 0.0 0.014 15.6 0.0 1.9 1 1 1 2 2 2 1 AAA domain RNA_helicase PF00910.17 KLO15491.1 - 0.008 16.3 0.0 0.04 14.0 0.0 2.0 2 0 0 2 2 2 1 RNA helicase Torsin PF06309.6 KLO15491.1 - 0.014 15.2 0.0 0.029 14.2 0.0 1.4 1 0 0 1 1 1 0 Torsin AAA_22 PF13401.1 KLO15491.1 - 0.03 14.4 0.0 0.068 13.3 0.0 1.7 1 1 0 1 1 1 0 AAA domain DUF2075 PF09848.4 KLO15491.1 - 0.048 12.6 0.0 0.088 11.7 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_19 PF13245.1 KLO15491.1 - 0.072 12.8 0.0 0.21 11.3 0.0 1.8 1 0 0 1 1 1 0 Part of AAA domain AAA_17 PF13207.1 KLO15491.1 - 0.077 13.8 0.2 0.18 12.6 0.1 2.0 1 1 0 1 1 1 0 AAA domain Pkinase_Tyr PF07714.12 KLO15492.1 - 7.3e-13 48.1 0.2 8.8e-13 47.9 0.1 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 KLO15492.1 - 3.1e-10 39.6 0.0 3.5e-10 39.4 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain DUF788 PF05620.6 KLO15494.1 - 4.7 7.0 10.5 0.46 10.3 3.0 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF788) LEP503 PF15221.1 KLO15495.1 - 0.14 11.8 5.2 0.23 11.1 2.0 2.2 2 0 0 2 2 2 0 Lens epithelial cell protein LEP503 iPGM_N PF06415.8 KLO15498.1 - 0.097 11.9 0.1 0.14 11.5 0.1 1.2 1 0 0 1 1 1 0 BPG-independent PGAM N-terminus (iPGM_N) Gemini_AC4_5_2 PF08464.5 KLO15498.1 - 0.1 12.3 1.4 0.2 11.4 1.0 1.4 1 0 0 1 1 1 0 Geminivirus AC4/5 conserved region Chorion_2 PF03964.10 KLO15498.1 - 1.5 9.4 7.5 2.9 8.4 5.2 1.6 1 1 0 1 1 1 0 Chorion family 2 GPI-anchored PF10342.4 KLO15499.1 - 1.2e-05 25.7 0.0 1.5e-05 25.3 0.0 1.1 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Ustilago_mating PF05722.7 KLO15500.1 - 1.7 7.8 10.4 2 7.6 7.2 1.3 1 0 0 1 1 1 0 Ustilago B locus mating-type protein Herpes_UL43 PF05072.8 KLO15501.1 - 0.092 11.4 0.3 0.14 10.8 0.2 1.2 1 0 0 1 1 1 0 Herpesvirus UL43 protein HLH PF00010.21 KLO15502.1 - 3.2e-11 42.7 0.1 7.1e-11 41.6 0.1 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain MYCBPAP PF14646.1 KLO15502.1 - 0.068 11.8 0.7 0.11 11.1 0.5 1.3 1 0 0 1 1 1 0 MYCBP-associated protein family Urm1 PF09138.6 KLO15503.1 - 1.6e-30 105.0 0.0 1.6e-24 85.8 0.0 2.0 1 1 1 2 2 2 2 Urm1 (Ubiquitin related modifier) ThiS PF02597.15 KLO15503.1 - 5.8e-06 26.6 0.0 8.3e-06 26.1 0.0 1.2 1 0 0 1 1 1 1 ThiS family GTP1_OBG PF01018.17 KLO15504.1 - 6.7e-35 120.0 3.7 1.1e-24 86.8 0.9 2.2 2 0 0 2 2 2 2 GTP1/OBG MMR_HSR1 PF01926.18 KLO15504.1 - 4.5e-16 58.8 0.0 1.3e-15 57.3 0.0 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase Arf PF00025.16 KLO15504.1 - 0.0007 18.8 0.1 0.73 9.0 0.0 2.3 2 0 0 2 2 2 2 ADP-ribosylation factor family FeoB_N PF02421.13 KLO15504.1 - 0.0011 18.2 0.0 0.0026 17.0 0.0 1.7 1 0 0 1 1 1 1 Ferrous iron transport protein B cobW PF02492.14 KLO15504.1 - 0.0015 17.9 0.3 0.071 12.5 0.2 2.3 1 1 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain GTP_EFTU PF00009.22 KLO15504.1 - 0.0019 17.6 0.1 1.2 8.5 0.0 2.2 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain ArgK PF03308.11 KLO15504.1 - 0.01 14.6 0.2 0.54 8.9 0.0 2.2 2 0 0 2 2 2 0 ArgK protein Dynamin_N PF00350.18 KLO15504.1 - 0.019 14.7 0.0 0.045 13.5 0.0 1.7 1 1 0 1 1 1 0 Dynamin family AAA_18 PF13238.1 KLO15504.1 - 0.021 15.1 2.6 0.034 14.4 0.0 2.5 2 1 0 2 2 2 0 AAA domain ABC_tran PF00005.22 KLO15504.1 - 0.08 13.2 0.0 0.18 12.1 0.0 1.6 1 0 0 1 1 1 0 ABC transporter TniB PF05621.6 KLO15504.1 - 0.09 11.5 0.2 0.17 10.6 0.1 1.4 1 0 0 1 1 1 0 Bacterial TniB protein Gtr1_RagA PF04670.7 KLO15504.1 - 0.15 11.2 0.0 0.22 10.6 0.0 1.3 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region AAA_17 PF13207.1 KLO15504.1 - 0.19 12.5 1.3 1.6 9.5 0.1 2.7 2 1 0 2 2 2 0 AAA domain AAA_28 PF13521.1 KLO15504.1 - 0.26 11.2 0.0 0.26 11.2 0.0 2.4 3 0 0 3 3 3 0 AAA domain p450 PF00067.17 KLO15505.1 - 1.9e-73 247.5 0.0 2.2e-73 247.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Pro-kuma_activ PF09286.6 KLO15506.1 - 2.1e-45 154.2 0.1 3.6e-45 153.5 0.1 1.4 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.17 KLO15506.1 - 1.6e-05 24.1 0.3 2.7e-05 23.4 0.2 1.3 1 0 0 1 1 1 1 Subtilase family DNA_pol_A_exo1 PF01612.15 KLO15508.1 - 6.1e-14 51.8 0.0 2e-06 27.4 0.0 2.3 2 0 0 2 2 2 2 3'-5' exonuclease TRAM1 PF08390.6 KLO15509.1 - 8.1 6.0 10.3 0.9 9.0 0.1 3.2 3 0 0 3 3 3 0 TRAM1-like protein Aminotran_1_2 PF00155.16 KLO15510.1 - 7.4e-39 133.7 0.0 1e-38 133.2 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Copper-fist PF00649.13 KLO15512.1 - 5.6e-22 76.6 7.4 8.6e-22 76.0 0.5 2.3 1 1 1 2 2 2 2 Copper fist DNA binding domain Ornatin PF02088.10 KLO15512.1 - 0.0036 16.8 3.8 0.0067 15.9 1.5 2.1 1 1 1 2 2 2 1 Ornatin zinc-ribbons_6 PF07191.7 KLO15512.1 - 0.043 13.6 4.7 0.056 13.2 3.2 1.2 1 0 0 1 1 1 0 zinc-ribbons LTP_2 PF14368.1 KLO15512.1 - 0.072 13.2 2.4 0.086 12.9 1.6 1.2 1 0 0 1 1 1 0 Probable lipid transfer Sprouty PF05210.8 KLO15512.1 - 0.075 13.0 0.9 0.075 13.0 0.6 1.8 2 0 0 2 2 2 0 Sprouty protein (Spry) DnaJ PF00226.26 KLO15514.1 - 8.2e-19 67.1 0.4 2.4e-18 65.6 0.3 1.9 1 0 0 1 1 1 1 DnaJ domain DUF4245 PF14030.1 KLO15514.1 - 0.34 10.6 0.1 0.34 10.6 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF4245) SUZ PF12752.2 KLO15515.1 - 2.8e-09 37.3 4.2 2.8e-09 37.3 2.9 2.7 2 1 1 3 3 3 1 SUZ domain SPATIAL PF15256.1 KLO15515.1 - 0.047 13.7 2.2 0.081 12.9 1.2 1.5 1 1 1 2 2 2 0 SPATIAL BSP_II PF05432.6 KLO15515.1 - 0.12 11.6 8.5 0.46 9.7 5.9 1.7 1 1 1 2 2 2 0 Bone sialoprotein II (BSP-II) Peptidase_M20 PF01546.23 KLO15516.1 - 3.4e-29 101.7 0.0 4.9e-29 101.1 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 KLO15516.1 - 1.2e-12 47.5 0.0 2e-12 46.8 0.0 1.3 1 0 0 1 1 1 1 Peptidase dimerisation domain Mito_carr PF00153.22 KLO15517.1 - 7e-67 221.1 8.3 6.2e-24 83.5 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Pro-kuma_activ PF09286.6 KLO15518.1 - 3e-46 157.0 0.0 7.4e-46 155.7 0.0 1.7 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.17 KLO15518.1 - 1.4e-07 30.9 0.2 2.3e-07 30.2 0.2 1.3 1 0 0 1 1 1 1 Subtilase family Dynamin_N PF00350.18 KLO15519.1 - 1.5e-12 47.6 0.0 1.1e-11 44.8 0.0 2.5 2 1 0 2 2 2 1 Dynamin family MMR_HSR1 PF01926.18 KLO15519.1 - 6.2e-05 22.9 0.0 0.1 12.5 0.0 3.1 2 0 0 2 2 2 2 50S ribosome-binding GTPase DUF4145 PF13643.1 KLO15519.1 - 0.005 16.6 0.1 5.6 6.8 0.0 3.1 2 0 0 2 2 2 2 Domain of unknown function (DUF4145) FtsK_SpoIIIE PF01580.13 KLO15519.1 - 0.05 13.0 0.2 5 6.5 0.0 2.9 2 1 0 2 2 2 0 FtsK/SpoIIIE family FhuF PF06276.7 KLO15519.1 - 0.079 12.9 0.1 0.22 11.4 0.1 1.7 1 0 0 1 1 1 0 Ferric iron reductase FhuF-like transporter eRF1_3 PF03465.10 KLO15519.1 - 0.37 11.0 3.6 0.37 11.0 0.1 2.6 3 0 0 3 3 3 0 eRF1 domain 3 Fungal_trans PF04082.13 KLO15520.1 - 6.5e-07 28.4 0.1 1.5e-06 27.3 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KLO15520.1 - 2.7e-05 23.9 9.1 5.3e-05 23.0 6.3 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 KLO15521.1 - 2.6e-37 128.1 0.1 7.7e-37 126.5 0.0 1.8 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KLO15521.1 - 1.5e-05 24.8 12.9 2.5e-05 24.0 9.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pro-kuma_activ PF09286.6 KLO15522.1 - 9e-47 158.7 0.1 1.9e-46 157.6 0.0 1.6 2 0 0 2 2 2 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.17 KLO15522.1 - 0.0019 17.3 0.6 0.003 16.7 0.4 1.3 1 0 0 1 1 1 1 Subtilase family Complex1_LYR PF05347.10 KLO15523.1 - 4.4e-05 23.1 2.4 5.5e-05 22.8 0.2 2.4 2 0 0 2 2 2 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 KLO15523.1 - 0.00042 20.4 2.1 0.0012 19.0 0.5 2.5 1 1 1 2 2 2 1 Complex1_LYR-like Dimer_Tnp_hAT PF05699.9 KLO15523.1 - 0.012 15.1 0.1 0.038 13.6 0.1 1.9 2 0 0 2 2 2 0 hAT family C-terminal dimerisation region Imm6 PF14434.1 KLO15523.1 - 0.19 11.4 0.3 3.4 7.4 0.0 2.2 2 0 0 2 2 2 0 Immunity protein Imm6 EST1_DNA_bind PF10373.4 KLO15524.1 - 3e-39 134.9 0.1 6e-39 133.9 0.0 1.5 1 0 0 1 1 1 1 Est1 DNA/RNA binding domain EST1 PF10374.4 KLO15524.1 - 8.4e-17 61.4 0.7 1.9e-16 60.2 0.3 1.8 2 0 0 2 2 2 1 Telomerase activating protein Est1 UCH PF00443.24 KLO15525.1 - 5.6e-12 45.3 0.4 6.2e-10 38.6 0.2 2.2 1 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase UBA_4 PF14555.1 KLO15525.1 - 1.1e-06 28.0 0.0 4.2e-06 26.1 0.0 1.9 2 0 0 2 2 2 1 UBA-like domain UBA PF00627.26 KLO15525.1 - 8.1e-05 22.3 0.0 0.0002 21.0 0.0 1.7 1 0 0 1 1 1 1 UBA/TS-N domain CUE PF02845.11 KLO15525.1 - 0.00017 20.9 0.2 0.00086 18.7 0.0 2.4 3 0 0 3 3 3 1 CUE domain UIM PF02809.15 KLO15525.1 - 0.00029 20.1 6.2 0.049 13.2 0.3 3.1 2 0 0 2 2 2 2 Ubiquitin interaction motif DivIC PF04977.10 KLO15525.1 - 0.26 10.8 4.2 4.7 6.7 0.0 4.4 4 1 1 5 5 5 0 Septum formation initiator Aminotran_1_2 PF00155.16 KLO15526.1 - 1.5e-54 185.3 0.0 9.3e-46 156.4 0.0 2.1 2 0 0 2 2 2 2 Aminotransferase class I and II Beta_elim_lyase PF01212.16 KLO15526.1 - 3.6e-05 23.0 0.0 5.1e-05 22.5 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase OKR_DC_1 PF01276.15 KLO15526.1 - 0.04 12.4 0.0 0.075 11.5 0.0 1.3 1 0 0 1 1 1 0 Orn/Lys/Arg decarboxylase, major domain UQ_con PF00179.21 KLO15527.1 - 2.8e-49 166.1 0.0 3.3e-49 165.9 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 KLO15527.1 - 5.6e-07 29.3 0.0 1.1e-06 28.4 0.0 1.4 1 1 0 1 1 1 1 Prokaryotic E2 family B UDPG_MGDP_dh_N PF03721.9 KLO15528.1 - 3e-58 196.2 0.0 5.5e-58 195.4 0.0 1.4 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain UDPG_MGDP_dh_C PF03720.10 KLO15528.1 - 6.3e-34 116.3 0.1 1.1e-32 112.3 0.0 2.2 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain UDPG_MGDP_dh PF00984.14 KLO15528.1 - 7.5e-31 106.2 0.0 1.4e-30 105.3 0.0 1.5 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, central domain NAD_Gly3P_dh_N PF01210.18 KLO15528.1 - 0.017 14.8 0.1 1.5 8.5 0.0 2.8 2 1 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Ldh_1_N PF00056.18 KLO15528.1 - 0.092 12.5 0.0 4 7.2 0.0 2.7 2 1 0 2 2 2 0 lactate/malate dehydrogenase, NAD binding domain F420_oxidored PF03807.12 KLO15528.1 - 0.1 13.0 0.1 2.7 8.4 0.0 3.0 3 1 0 3 3 3 0 NADP oxidoreductase coenzyme F420-dependent Saccharop_dh PF03435.13 KLO15528.1 - 0.11 11.4 0.0 0.21 10.5 0.0 1.4 1 0 0 1 1 1 0 Saccharopine dehydrogenase CTP_transf_1 PF01148.15 KLO15529.1 - 2.2e-11 43.9 11.0 0.0005 19.8 1.1 3.1 2 1 1 3 3 3 3 Cytidylyltransferase family Ribosomal_S17e PF00833.13 KLO15530.1 - 1.4e-56 189.4 0.3 1.7e-56 189.2 0.2 1.0 1 0 0 1 1 1 1 Ribosomal S17 Ribosomal_S8 PF00410.14 KLO15531.1 - 9.2e-26 90.1 0.0 1.3e-25 89.7 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S8 Ebola_NP PF05505.7 KLO15531.1 - 0.12 10.4 0.0 0.12 10.4 0.0 1.1 1 0 0 1 1 1 0 Ebola nucleoprotein Whi5 PF08528.6 KLO15532.1 - 4.5e-07 29.2 1.1 4.5e-07 29.2 0.8 1.8 2 0 0 2 2 2 1 Whi5 like Vps4_C PF09336.5 KLO15532.1 - 0.033 14.0 0.5 0.88 9.5 0.0 2.4 2 0 0 2 2 2 0 Vps4 C terminal oligomerisation domain RbsD_FucU PF05025.8 KLO15533.1 - 0.045 14.0 0.0 0.08 13.2 0.0 1.4 1 0 0 1 1 1 0 RbsD / FucU transport protein family zf-CCHC_5 PF14787.1 KLO15535.1 - 4.4e-05 22.8 0.6 7.8e-05 22.0 0.4 1.5 1 0 0 1 1 1 1 GAG-polyprotein viral zinc-finger zf-CCHC PF00098.18 KLO15535.1 - 0.00012 21.8 1.0 0.00016 21.4 0.7 1.2 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_3 PF13917.1 KLO15535.1 - 0.0018 17.9 0.2 0.003 17.2 0.1 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.1 KLO15535.1 - 0.11 12.0 0.1 0.16 11.4 0.0 1.3 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_4 PF14392.1 KLO15535.1 - 0.16 11.6 0.4 0.24 11.1 0.3 1.3 1 0 0 1 1 1 0 Zinc knuckle NDT80_PhoG PF05224.7 KLO15536.1 - 0.015 15.3 0.4 0.043 13.8 0.2 1.8 1 1 0 1 1 1 0 NDT80 / PhoG like DNA-binding family Mre11_DNA_bind PF04152.9 KLO15537.1 - 1.9e-47 161.3 0.0 1.9e-47 161.3 0.0 2.3 3 0 0 3 3 3 1 Mre11 DNA-binding presumed domain Metallophos PF00149.23 KLO15537.1 - 4.6e-24 84.9 0.1 7.9e-24 84.1 0.1 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 KLO15537.1 - 5.1e-08 32.8 0.0 2e-07 30.9 0.0 2.0 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain SNF2_N PF00176.18 KLO15540.1 - 8.7e-78 261.1 0.1 1.2e-77 260.6 0.1 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 KLO15540.1 - 6.9e-17 61.0 0.0 2e-16 59.6 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HDA2-3 PF11496.3 KLO15540.1 - 0.00011 21.1 2.7 0.064 12.0 0.0 2.9 3 0 0 3 3 3 2 Class II histone deacetylase complex subunits 2 and 3 ResIII PF04851.10 KLO15540.1 - 0.00088 19.1 0.0 0.0021 17.9 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C_4 PF13871.1 KLO15540.1 - 0.044 13.2 0.0 0.1 12.0 0.0 1.6 1 1 0 1 1 1 0 Helicase_C-like zf-TFIIB PF13453.1 KLO15540.1 - 0.3 10.3 2.8 0.62 9.3 1.9 1.6 1 0 0 1 1 1 0 Transcription factor zinc-finger Epimerase PF01370.16 KLO15541.1 - 8.7e-51 172.6 0.0 1.1e-50 172.2 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.12 KLO15541.1 - 1.5e-05 24.0 0.0 9.9e-05 21.3 0.0 2.1 2 1 0 3 3 3 1 RmlD substrate binding domain 3Beta_HSD PF01073.14 KLO15541.1 - 0.00078 18.2 0.0 0.0013 17.5 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.10 KLO15541.1 - 0.0036 16.2 4.4 0.05 12.4 2.2 2.5 2 1 0 2 2 2 1 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.7 KLO15541.1 - 0.0038 16.1 0.1 0.05 12.5 0.0 2.1 2 0 0 2 2 2 1 Male sterility protein PSII_Pbs27 PF13326.1 KLO15541.1 - 0.074 13.0 0.0 0.3 11.0 0.0 1.9 2 0 0 2 2 2 0 Photosystem II Pbs27 Epimerase PF01370.16 KLO15542.1 - 1.5e-67 227.4 0.0 2.2e-67 226.9 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.12 KLO15542.1 - 7.1e-06 25.1 0.0 4.1e-05 22.6 0.0 1.9 1 1 0 1 1 1 1 RmlD substrate binding domain NAD_binding_10 PF13460.1 KLO15542.1 - 0.0023 17.9 0.0 0.0055 16.7 0.0 1.8 2 0 0 2 2 2 1 NADH(P)-binding Polysacc_synt_2 PF02719.10 KLO15542.1 - 0.0026 16.7 0.0 0.0093 14.8 0.0 1.8 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein NmrA PF05368.8 KLO15542.1 - 0.04 13.1 0.0 0.065 12.4 0.0 1.4 1 0 0 1 1 1 0 NmrA-like family Epimerase_Csub PF13950.1 KLO15542.1 - 0.13 12.1 0.0 0.29 11.1 0.0 1.5 1 0 0 1 1 1 0 UDP-glucose 4-epimerase C-term subunit TPT PF03151.11 KLO15543.1 - 9.4e-08 31.8 13.4 9.4e-08 31.8 9.3 2.8 2 1 0 2 2 2 1 Triose-phosphate Transporter family EamA PF00892.15 KLO15543.1 - 0.0022 17.9 37.1 0.067 13.2 11.4 2.4 2 1 0 2 2 2 2 EamA-like transporter family PAPS_reduct PF01507.14 KLO15544.1 - 1.8e-27 96.2 0.0 4.8e-27 94.8 0.0 1.6 1 1 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family Meleagrin PF08189.6 KLO15544.1 - 4 6.9 5.6 0.53 9.7 0.4 1.9 2 0 0 2 2 2 0 Meleagrin/Cygnin family Pkinase PF00069.20 KLO15545.1 - 1.2e-20 73.8 0.0 2e-20 73.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain WD40 PF00400.27 KLO15545.1 - 1.1e-17 63.1 14.3 3.3e-09 36.2 0.4 6.1 5 0 0 5 5 5 3 WD domain, G-beta repeat Pkinase_Tyr PF07714.12 KLO15545.1 - 2.9e-09 36.3 0.0 1.3e-08 34.2 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase HEAT PF02985.17 KLO15545.1 - 8.7e-08 31.6 8.9 0.0037 17.2 0.1 5.1 5 0 0 5 5 5 3 HEAT repeat HEAT_2 PF13646.1 KLO15545.1 - 2.9e-06 27.4 0.8 0.0038 17.4 0.2 3.1 2 1 0 2 2 2 2 HEAT repeats APH PF01636.18 KLO15545.1 - 0.031 14.0 0.0 0.071 12.8 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family Cnd1 PF12717.2 KLO15545.1 - 0.081 12.7 1.5 3.8 7.3 0.0 2.8 3 0 0 3 3 3 0 non-SMC mitotic condensation complex subunit 1 ArfGap PF01412.13 KLO15548.1 - 2.8e-41 139.9 0.7 4.8e-41 139.2 0.5 1.4 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf UcrQ PF02939.11 KLO15549.1 - 3.2e-21 74.9 0.8 3.9e-21 74.6 0.5 1.1 1 0 0 1 1 1 1 UcrQ family HSP20 PF00011.16 KLO15550.1 - 8.6e-15 54.4 0.0 9.9e-15 54.2 0.0 1.0 1 0 0 1 1 1 1 Hsp20/alpha crystallin family zf-RING_2 PF13639.1 KLO15551.1 - 1.8e-08 34.0 2.5 1.8e-08 34.0 1.8 2.2 2 1 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.1 KLO15551.1 - 2.1e-08 34.0 1.7 2.1e-08 34.0 1.1 2.9 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KLO15551.1 - 1.1e-07 31.3 0.3 1.1e-07 31.3 0.2 2.9 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KLO15551.1 - 3.9e-07 29.6 2.8 3.9e-07 29.6 1.9 2.6 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KLO15551.1 - 1e-05 25.1 3.0 1e-05 25.1 2.1 2.5 2 1 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 KLO15551.1 - 5.6e-05 22.9 4.1 5.6e-05 22.9 2.8 2.9 3 0 0 3 3 3 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 KLO15551.1 - 0.00057 19.5 0.3 0.0016 18.1 0.2 1.8 1 0 0 1 1 1 1 RING-type zinc-finger zf-MIZ PF02891.15 KLO15551.1 - 0.095 12.2 6.1 0.035 13.6 1.4 2.1 2 0 0 2 2 2 0 MIZ/SP-RING zinc finger UPF0547 PF10571.4 KLO15551.1 - 4.1 7.1 7.5 2.7 7.7 0.3 3.0 3 0 0 3 3 3 0 Uncharacterised protein family UPF0547 RNA_pol_A_bac PF01000.21 KLO15553.1 - 1.3e-26 92.9 0.0 2.3e-26 92.1 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.19 KLO15553.1 - 3.7e-11 41.9 0.0 5.4e-11 41.4 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain WD40 PF00400.27 KLO15554.1 - 4.1e-34 115.2 16.1 1.6e-08 34.0 0.1 6.5 6 0 0 6 6 6 5 WD domain, G-beta repeat NACHT PF05729.7 KLO15554.1 - 2.4e-10 40.2 0.8 3.8e-09 36.4 0.1 2.7 2 1 0 2 2 2 1 NACHT domain AAA_16 PF13191.1 KLO15554.1 - 8.8e-07 29.0 0.4 3.2e-06 27.2 0.2 2.0 2 0 0 2 2 2 1 AAA ATPase domain NB-ARC PF00931.17 KLO15554.1 - 0.0043 15.9 0.0 0.008 15.0 0.0 1.4 1 0 0 1 1 1 1 NB-ARC domain AAA_22 PF13401.1 KLO15554.1 - 0.0069 16.5 0.0 0.028 14.5 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA PF00004.24 KLO15554.1 - 0.019 15.1 0.0 0.065 13.4 0.0 2.0 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) CSTF2_hinge PF14327.1 KLO15555.1 - 2.7e-25 88.2 2.7 5.8e-25 87.1 1.1 2.2 2 0 0 2 2 2 1 Hinge domain of cleavage stimulation factor subunit 2 RRM_1 PF00076.17 KLO15555.1 - 2.1e-21 75.2 0.0 3.2e-21 74.7 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KLO15555.1 - 2.4e-15 56.2 0.0 5.9e-15 55.0 0.0 1.6 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) CSTF_C PF14304.1 KLO15555.1 - 7e-10 38.0 3.7 1.5e-09 36.9 2.5 1.5 1 0 0 1 1 1 1 Transcription termination and cleavage factor C-terminal RRM_5 PF13893.1 KLO15555.1 - 4.6e-07 29.5 0.0 7.6e-07 28.8 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SNF5 PF04855.7 KLO15556.1 - 2.2e-67 227.0 1.3 2.2e-67 227.0 0.9 1.8 2 0 0 2 2 2 1 SNF5 / SMARCB1 / INI1 Elf1 PF05129.8 KLO15556.1 - 0.035 13.7 0.4 0.084 12.5 0.3 1.6 1 0 0 1 1 1 0 Transcription elongation factor Elf1 like GATA PF00320.22 KLO15556.1 - 0.036 13.4 5.8 0.069 12.5 4.0 1.5 1 0 0 1 1 1 0 GATA zinc finger K_channel_TID PF07941.6 KLO15557.1 - 0.3 11.3 8.7 0.032 14.4 1.5 2.7 2 0 0 2 2 2 0 Potassium channel Kv1.4 tandem inactivation domain F-box-like PF12937.2 KLO15558.1 - 3.1e-08 33.2 5.0 3.2e-08 33.1 0.4 2.7 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 KLO15558.1 - 3.5e-08 32.9 1.9 3.5e-08 32.9 1.4 2.9 3 0 0 3 3 3 1 F-box domain F-box PF00646.28 KLO15559.1 - 2.3e-06 27.0 0.4 7.2e-06 25.5 0.3 1.9 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 KLO15559.1 - 2.7e-06 26.9 0.2 6.6e-06 25.7 0.1 1.7 1 0 0 1 1 1 1 F-box-like IBR PF01485.16 KLO15560.1 - 0.53 10.2 8.5 1.5 8.7 5.9 1.7 1 0 0 1 1 1 0 IBR domain RNA_POL_M_15KD PF02150.11 KLO15560.1 - 9.9 5.9 12.9 0.36 10.5 4.4 2.2 2 1 0 2 2 2 0 RNA polymerases M/15 Kd subunit F-box PF00646.28 KLO15561.1 - 2.3e-06 27.0 1.8 6.3e-06 25.7 1.3 1.8 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 KLO15561.1 - 0.00041 20.0 0.8 0.00041 20.0 0.6 2.7 2 0 0 2 2 2 1 F-box-like LtrA PF06772.6 KLO15564.1 - 1.6e-20 73.3 14.8 1.3e-12 47.3 6.1 2.7 2 1 0 2 2 2 2 Bacterial low temperature requirement A protein (LtrA) Serine_rich PF08824.5 KLO15565.1 - 0.0034 17.1 0.2 0.0039 16.9 0.1 1.2 1 0 0 1 1 1 1 Serine rich protein interaction domain Remorin_C PF03763.8 KLO15565.1 - 0.0056 16.2 0.4 0.0076 15.7 0.3 1.2 1 0 0 1 1 1 1 Remorin, C-terminal region TMF_TATA_bd PF12325.3 KLO15565.1 - 0.041 13.6 2.1 1.8 8.2 0.0 2.3 1 1 0 2 2 2 0 TATA element modulatory factor 1 TATA binding MAD PF05557.8 KLO15565.1 - 0.053 11.6 0.2 0.064 11.3 0.1 1.0 1 0 0 1 1 1 0 Mitotic checkpoint protein YlbD_coat PF14071.1 KLO15565.1 - 0.061 13.3 0.4 0.16 12.0 0.3 1.6 1 1 0 1 1 1 0 Putative coat protein Fib_alpha PF08702.5 KLO15565.1 - 0.18 11.9 1.4 0.31 11.1 1.0 1.4 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family CENP-H PF05837.7 KLO15565.1 - 0.21 11.7 3.4 0.22 11.6 1.6 1.5 2 0 0 2 2 2 0 Centromere protein H (CENP-H) DivIVA PF05103.8 KLO15565.1 - 2.1 8.3 5.4 7.3 6.6 3.8 1.7 1 1 0 1 1 1 0 DivIVA protein p450 PF00067.17 KLO15569.1 - 2.3e-60 204.4 0.0 6.1e-60 203.0 0.0 1.6 1 1 0 1 1 1 1 Cytochrome P450 ACOX PF01756.14 KLO15570.1 - 1.5e-22 79.8 0.0 2.7e-22 79.0 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA oxidase Acyl-CoA_ox_N PF14749.1 KLO15570.1 - 1.2e-12 48.2 0.0 2.2e-12 47.3 0.0 1.4 1 0 0 1 1 1 1 Acyl-coenzyme A oxidase N-terminal Acyl-CoA_dh_M PF02770.14 KLO15570.1 - 1.3e-08 34.2 0.2 7.3e-08 31.7 0.1 2.3 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.19 KLO15570.1 - 2.2e-05 24.6 0.1 5.8e-05 23.2 0.1 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain TPP_enzyme_N PF02776.13 KLO15571.1 - 1.8e-34 118.7 0.1 3.3e-33 114.5 0.0 2.2 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.16 KLO15571.1 - 5.4e-20 71.5 0.1 9.7e-20 70.6 0.0 1.4 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.17 KLO15571.1 - 7.4e-15 54.9 0.0 1.4e-13 50.7 0.0 2.7 3 0 0 3 3 3 1 Thiamine pyrophosphate enzyme, central domain XFP_N PF09364.5 KLO15571.1 - 0.0032 16.0 0.1 0.0046 15.5 0.1 1.1 1 0 0 1 1 1 1 XFP N-terminal domain F-box-like PF12937.2 KLO15572.1 - 6.8e-06 25.7 0.1 2.2e-05 24.0 0.1 1.9 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KLO15572.1 - 0.077 12.6 0.9 0.32 10.6 0.0 2.5 3 0 0 3 3 3 0 F-box domain LRR_4 PF12799.2 KLO15572.1 - 0.52 9.9 5.4 13 5.5 2.4 3.3 2 1 1 3 3 3 0 Leucine Rich repeats (2 copies) F-box-like PF12937.2 KLO15573.1 - 0.011 15.4 0.2 0.011 15.4 0.1 2.4 3 0 0 3 3 3 0 F-box-like Myosin_tail_1 PF01576.14 KLO15574.1 - 0.00024 19.0 18.7 0.00024 19.0 13.0 2.4 2 1 0 2 2 2 1 Myosin tail Tho2 PF11262.3 KLO15574.1 - 0.065 12.2 3.2 0.16 11.0 2.2 1.6 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 FMO-like PF00743.14 KLO15576.1 - 5e-20 71.1 0.0 2.7e-18 65.4 0.0 2.7 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 KLO15576.1 - 1.8e-18 67.3 0.0 4.1e-18 66.1 0.0 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 KLO15576.1 - 4.7e-13 48.7 0.0 1.2e-08 34.3 0.0 2.8 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 KLO15576.1 - 4.4e-08 33.2 0.0 6.4e-06 26.1 0.0 2.3 1 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 KLO15576.1 - 1.1e-07 32.1 0.0 0.026 14.9 0.1 3.6 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase 2-Hacid_dh_C PF02826.14 KLO15576.1 - 0.0001 21.5 0.0 0.036 13.2 0.0 2.2 2 0 0 2 2 2 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DAO PF01266.19 KLO15576.1 - 0.0041 16.0 0.6 6 5.6 0.1 3.3 2 1 0 3 3 3 2 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 KLO15576.1 - 0.0048 16.0 0.0 0.013 14.5 0.1 1.7 2 0 0 2 2 2 1 FAD binding domain FAD_binding_2 PF00890.19 KLO15576.1 - 0.0056 15.5 0.0 0.016 14.0 0.1 1.7 2 0 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.1 KLO15576.1 - 0.0062 16.5 0.0 0.049 13.6 0.0 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain 3HCDH_N PF02737.13 KLO15576.1 - 0.015 14.9 0.0 0.28 10.8 0.0 2.2 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain GIDA PF01134.17 KLO15576.1 - 0.093 11.5 0.1 1.4 7.7 0.0 2.2 2 0 0 2 2 2 0 Glucose inhibited division protein A Thi4 PF01946.12 KLO15576.1 - 0.13 11.3 0.0 1.2 8.2 0.0 2.1 2 0 0 2 2 2 0 Thi4 family GMC_oxred_N PF00732.14 KLO15577.1 - 8.5e-56 189.2 0.0 1.1e-55 188.9 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 KLO15577.1 - 7.8e-35 120.2 0.1 1.3e-34 119.5 0.1 1.3 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.1 KLO15577.1 - 2.7e-06 27.3 0.1 0.00055 19.8 0.1 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 KLO15577.1 - 9.9e-05 21.3 0.0 0.00053 18.9 0.0 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 KLO15577.1 - 0.0011 19.1 0.3 0.21 11.6 0.1 2.4 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 KLO15577.1 - 0.0023 16.9 0.1 0.0036 16.2 0.1 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_binding_2 PF00890.19 KLO15577.1 - 0.0034 16.3 0.2 0.0058 15.5 0.2 1.3 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.9 KLO15577.1 - 0.012 14.1 0.1 0.064 11.7 0.0 1.9 2 0 0 2 2 2 0 HI0933-like protein Pyr_redox_2 PF07992.9 KLO15577.1 - 0.016 15.0 0.0 0.036 13.9 0.0 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 KLO15577.1 - 0.026 14.3 0.0 0.32 10.7 0.1 2.3 2 0 0 2 2 2 0 FAD-NAD(P)-binding K_oxygenase PF13434.1 KLO15577.1 - 0.063 12.1 0.0 0.094 11.6 0.0 1.2 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) HTH_29 PF13551.1 KLO15581.1 - 9.2e-05 22.5 0.1 9.9e-05 22.4 0.0 1.0 1 0 0 1 1 1 1 Winged helix-turn helix HTH_32 PF13565.1 KLO15581.1 - 9.9e-05 23.0 0.0 0.00011 22.9 0.0 1.0 1 0 0 1 1 1 1 Homeodomain-like domain DDE_3 PF13358.1 KLO15582.1 - 8.9e-12 44.9 0.0 1.1e-11 44.7 0.0 1.0 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_3 PF13358.1 KLO15583.1 - 4.6e-09 36.1 0.0 6.8e-09 35.6 0.0 1.3 1 1 0 1 1 1 1 DDE superfamily endonuclease Peripla_BP_1 PF00532.16 KLO15584.1 - 0.02 14.0 0.2 0.056 12.6 0.0 1.7 2 0 0 2 2 2 0 Periplasmic binding proteins and sugar binding domain of LacI family F-box-like PF12937.2 KLO15586.1 - 3.6e-07 29.8 0.7 8.4e-07 28.6 0.1 1.9 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 KLO15586.1 - 0.038 13.6 0.2 0.31 10.7 0.2 2.4 1 1 0 1 1 1 0 F-box domain NIR_SIR_ferr PF03460.12 KLO15586.1 - 0.14 11.7 0.0 0.76 9.4 0.0 2.1 2 0 0 2 2 2 0 Nitrite/Sulfite reductase ferredoxin-like half domain Lipase_GDSL_2 PF13472.1 KLO15587.1 - 4.9e-14 52.8 0.1 1e-13 51.7 0.1 1.5 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 KLO15587.1 - 1.2e-06 28.5 0.9 6e-06 26.2 0.6 2.2 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase HUN PF08729.5 KLO15589.1 - 3e-11 42.9 0.0 7.1e-11 41.8 0.0 1.7 1 0 0 1 1 1 1 HPC2 and ubinuclein domain UBN_AB PF14075.1 KLO15589.1 - 3.1e-08 33.5 0.0 8.7e-05 22.2 0.0 2.4 2 0 0 2 2 2 2 Ubinuclein conserved middle domain Velvet PF11754.3 KLO15593.1 - 3.9e-39 134.3 0.0 1.1e-20 74.0 0.0 2.4 1 1 1 2 2 2 2 Velvet factor MFS_1 PF07690.11 KLO15595.1 - 7.2e-23 80.8 21.1 1.1e-22 80.2 14.6 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily La PF05383.12 KLO15596.1 - 1.6e-19 69.4 0.0 2.7e-19 68.6 0.0 1.4 1 0 0 1 1 1 1 La domain RRM_1 PF00076.17 KLO15596.1 - 5.6e-06 25.9 0.1 2.4e-05 23.8 0.1 2.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KLO15596.1 - 6.9e-06 25.9 0.0 1.7e-05 24.6 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) DUF1943 PF09172.6 KLO15596.1 - 0.28 10.0 3.6 0.79 8.5 2.0 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF1943) API5 PF05918.6 KLO15596.1 - 2.9 6.3 8.7 5 5.4 6.1 1.4 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) AMP-binding PF00501.23 KLO15597.1 - 3.1e-83 279.5 0.1 4.2e-83 279.0 0.1 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 KLO15597.1 - 0.0017 19.2 0.0 0.0086 16.9 0.0 2.2 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Methyltransf_23 PF13489.1 KLO15598.1 - 4.4e-12 46.0 0.0 1.6e-11 44.1 0.0 1.9 1 1 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 KLO15598.1 - 4.3e-09 36.7 0.0 1e-08 35.5 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KLO15598.1 - 2.6e-07 30.3 0.0 8.5e-07 28.6 0.0 1.9 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 KLO15598.1 - 3.5e-05 24.2 0.0 7.7e-05 23.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 KLO15598.1 - 0.00053 19.0 0.0 0.0021 17.1 0.0 1.9 2 0 0 2 2 2 1 Putative methyltransferase Methyltransf_18 PF12847.2 KLO15598.1 - 0.00054 20.5 0.0 0.003 18.1 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KLO15598.1 - 0.011 16.0 0.0 0.06 13.7 0.0 2.2 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_26 PF13659.1 KLO15598.1 - 0.02 14.9 0.0 0.49 10.4 0.0 2.5 2 1 0 2 2 2 0 Methyltransferase domain DOT1 PF08123.8 KLO15598.1 - 0.052 12.8 0.0 0.08 12.2 0.0 1.2 1 0 0 1 1 1 0 Histone methylation protein DOT1 DNA_pol_lambd_f PF10391.4 KLO15599.1 - 6e-20 70.5 0.1 1.5e-17 62.8 0.0 3.2 3 0 0 3 3 3 1 Fingers domain of DNA polymerase lambda HHH_8 PF14716.1 KLO15599.1 - 1.3e-18 66.8 0.1 3.1e-17 62.5 0.1 2.6 2 0 0 2 2 2 1 Helix-hairpin-helix domain DNA_pol_B_thumb PF14791.1 KLO15599.1 - 4.2e-18 64.7 0.1 8.6e-18 63.7 0.1 1.6 1 0 0 1 1 1 1 DNA polymerase beta thumb DNA_pol_B_palm PF14792.1 KLO15599.1 - 2.4e-15 56.5 0.0 4.9e-15 55.5 0.0 1.6 1 0 0 1 1 1 1 DNA polymerase beta palm HHH_5 PF14520.1 KLO15599.1 - 9.3e-07 28.9 0.0 0.19 11.9 0.0 3.5 3 0 0 3 3 3 2 Helix-hairpin-helix domain HHH PF00633.18 KLO15599.1 - 4.2e-05 23.0 0.6 0.0067 16.0 0.0 2.8 2 0 0 2 2 2 1 Helix-hairpin-helix motif BRCT PF00533.21 KLO15599.1 - 0.0054 16.8 0.0 0.013 15.6 0.0 1.7 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain Cdd1 PF11731.3 KLO15599.1 - 0.011 15.5 0.0 0.65 9.9 0.0 3.7 3 1 1 4 4 4 0 Pathogenicity locus 5_3_exonuc PF01367.15 KLO15599.1 - 0.012 15.8 0.2 2 8.6 0.0 2.5 1 1 1 2 2 2 0 5'-3' exonuclease, C-terminal SAM fold HHH_2 PF12826.2 KLO15599.1 - 0.056 13.3 0.1 1.9 8.4 0.0 3.0 2 1 2 4 4 4 0 Helix-hairpin-helix motif DUF3701 PF12482.3 KLO15599.1 - 0.15 11.8 0.0 8.2 6.2 0.0 2.5 2 0 0 2 2 2 0 Phage integrase protein Peptidase_M16 PF00675.15 KLO15600.1 - 3e-24 85.4 0.0 7.9e-24 84.1 0.0 1.7 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.16 KLO15600.1 - 4.3e-08 33.0 0.0 1.3e-07 31.4 0.0 1.9 2 0 0 2 2 2 1 Peptidase M16 inactive domain Pheromone PF08015.6 KLO15601.1 - 0.048 14.4 1.7 0.048 14.4 1.2 5.9 3 1 1 4 4 4 0 Fungal mating-type pheromone P12 PF12669.2 KLO15601.1 - 0.48 10.6 2.3 0.95 9.7 1.6 1.4 1 0 0 1 1 1 0 Virus attachment protein p12 family F-box PF00646.28 KLO15603.1 - 4.5e-05 22.9 1.1 0.00016 21.2 0.8 2.0 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 KLO15603.1 - 0.023 14.3 0.6 0.087 12.5 0.4 2.1 1 0 0 1 1 1 0 F-box-like CRAL_TRIO_2 PF13716.1 KLO15605.1 - 0.041 13.7 1.1 3 7.7 0.1 2.1 1 1 1 2 2 2 0 Divergent CRAL/TRIO domain Fels1 PF05666.6 KLO15605.1 - 0.11 11.8 0.0 0.28 10.5 0.0 1.7 1 0 0 1 1 1 0 Fels-1 Prophage Protein-like TFIIA PF03153.8 KLO15606.1 - 0.033 14.0 7.3 0.041 13.7 5.0 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SKG6 PF08693.5 KLO15606.1 - 0.89 8.9 0.0 0.89 8.9 0.0 3.0 2 0 0 2 2 2 0 Transmembrane alpha-helix domain Adaptin_N PF01602.15 KLO15607.1 - 1.5e-152 508.6 5.6 1.9e-152 508.2 3.9 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.2 KLO15607.1 - 1.3e-26 93.4 2.6 6.6e-24 84.7 0.1 3.9 5 0 0 5 5 5 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.1 KLO15607.1 - 1.2e-19 70.3 2.8 2.4e-09 37.3 0.0 5.7 1 1 5 6 6 6 6 HEAT repeats HEAT PF02985.17 KLO15607.1 - 7.8e-13 47.3 2.2 0.00018 21.2 0.1 5.2 4 0 0 4 4 4 3 HEAT repeat HEAT_EZ PF13513.1 KLO15607.1 - 8e-07 29.3 6.3 0.027 14.9 0.1 6.6 7 1 1 8 8 8 2 HEAT-like repeat CLASP_N PF12348.3 KLO15607.1 - 0.00052 19.4 0.9 0.25 10.6 0.0 3.6 3 1 1 4 4 4 2 CLASP N terminal Arm PF00514.18 KLO15607.1 - 0.044 13.6 3.9 13 5.8 0.0 4.9 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat GMC_oxred_N PF00732.14 KLO15608.1 - 1.5e-54 185.1 0.0 1.9e-54 184.8 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 KLO15608.1 - 8.9e-34 116.8 0.0 1.4e-33 116.1 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 KLO15608.1 - 1e-06 27.9 0.0 2e-06 26.9 0.0 1.5 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KLO15608.1 - 1.4e-06 28.2 0.1 6.1e-05 22.9 0.3 2.6 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 KLO15608.1 - 0.00019 20.4 0.8 0.011 14.6 0.2 2.2 2 0 0 2 2 2 1 FAD binding domain Lycopene_cycl PF05834.7 KLO15608.1 - 0.0017 17.3 0.1 0.0026 16.7 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_3 PF13738.1 KLO15608.1 - 0.0026 17.8 0.0 2.3 8.2 0.0 2.8 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 KLO15608.1 - 0.0028 16.1 0.0 0.041 12.3 0.0 2.1 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox PF00070.22 KLO15608.1 - 0.014 15.7 0.2 0.27 11.6 0.0 2.9 4 0 0 4 4 3 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 KLO15608.1 - 0.025 14.4 0.1 0.09 12.6 0.0 2.0 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 KLO15608.1 - 0.037 13.8 0.0 0.098 12.4 0.0 1.7 2 0 0 2 2 2 0 FAD-NAD(P)-binding K_oxygenase PF13434.1 KLO15608.1 - 0.066 12.1 0.0 0.11 11.4 0.0 1.3 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) FAD_binding_3 PF01494.14 KLO15608.1 - 0.15 11.0 0.0 0.27 10.2 0.0 1.4 1 0 0 1 1 1 0 FAD binding domain GMC_oxred_N PF00732.14 KLO15610.1 - 1.2e-65 221.5 0.0 1.6e-65 221.2 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 KLO15610.1 - 1.3e-35 122.8 0.0 2e-35 122.1 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.19 KLO15610.1 - 0.0015 17.4 0.3 0.18 10.6 0.1 2.2 2 0 0 2 2 2 2 FAD binding domain Lycopene_cycl PF05834.7 KLO15610.1 - 0.0038 16.2 0.1 0.0056 15.6 0.1 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein DAO PF01266.19 KLO15610.1 - 0.0059 15.5 0.2 0.033 13.1 0.1 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KLO15610.1 - 0.0094 15.9 0.1 0.023 14.7 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 KLO15610.1 - 0.036 13.9 0.1 0.079 12.8 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.13 KLO15610.1 - 0.088 12.8 0.0 0.19 11.7 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain Thi4 PF01946.12 KLO15610.1 - 0.12 11.5 0.1 0.2 10.7 0.0 1.3 1 0 0 1 1 1 0 Thi4 family HI0933_like PF03486.9 KLO15610.1 - 0.12 10.8 0.1 0.22 9.9 0.1 1.4 1 0 0 1 1 1 0 HI0933-like protein Trp_halogenase PF04820.9 KLO15610.1 - 0.14 10.7 0.2 0.28 9.7 0.2 1.5 1 0 0 1 1 1 0 Tryptophan halogenase DUF3481 PF11980.3 KLO15612.1 - 0.11 12.3 2.4 0.31 10.8 0.0 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF3481) GMC_oxred_N PF00732.14 KLO15613.1 - 1.6e-60 204.8 0.0 2.1e-60 204.3 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 KLO15613.1 - 1.3e-36 126.0 0.0 2e-36 125.4 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_N PF00732.14 KLO15614.1 - 3.5e-65 220.0 0.0 4.3e-65 219.7 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 KLO15614.1 - 5e-38 130.6 0.0 7.6e-38 130.0 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.19 KLO15614.1 - 0.0016 17.3 1.2 0.11 11.3 0.3 2.2 2 0 0 2 2 2 2 FAD binding domain Lycopene_cycl PF05834.7 KLO15614.1 - 0.0045 15.9 0.2 0.0067 15.3 0.1 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein DAO PF01266.19 KLO15614.1 - 0.0054 15.6 1.2 0.008 15.1 0.3 1.6 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KLO15614.1 - 0.0058 16.6 0.1 0.018 15.0 0.1 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 KLO15614.1 - 0.016 15.1 0.4 0.062 13.1 0.1 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 KLO15614.1 - 0.046 12.8 0.1 0.094 11.7 0.1 1.4 1 0 0 1 1 1 0 Thi4 family p450 PF00067.17 KLO15615.1 - 1.4e-50 172.2 0.0 2.3e-49 168.1 0.0 2.0 1 1 0 1 1 1 1 Cytochrome P450 F-box-like PF12937.2 KLO15617.1 - 0.00048 19.8 1.1 0.0022 17.6 0.2 2.6 3 0 0 3 3 3 1 F-box-like DEAD PF00270.24 KLO15618.1 - 1.7e-09 37.4 0.0 4.4e-08 32.7 0.0 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KLO15618.1 - 0.13 12.1 0.0 0.53 10.1 0.0 2.1 1 0 0 1 1 1 0 Helicase conserved C-terminal domain p450 PF00067.17 KLO15619.1 - 6.3e-56 189.8 0.0 8e-56 189.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 APOBEC_C PF05240.9 KLO15619.1 - 0.097 12.0 0.0 0.21 11.0 0.0 1.5 1 0 0 1 1 1 0 APOBEC-like C-terminal domain UbiA PF01040.13 KLO15620.1 - 3.8e-22 78.7 7.8 5.1e-22 78.3 5.4 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family F-box-like PF12937.2 KLO15621.1 - 0.0031 17.1 0.1 0.0088 15.7 0.0 1.9 1 0 0 1 1 1 1 F-box-like F-box-like PF12937.2 KLO15622.1 - 1.7e-05 24.4 0.2 4.7e-05 23.0 0.1 1.8 1 0 0 1 1 1 1 F-box-like NOA36 PF06524.7 KLO15622.1 - 0.25 10.5 11.6 0.37 10.0 8.0 1.2 1 0 0 1 1 1 0 NOA36 protein p450 PF00067.17 KLO15623.1 - 3.1e-68 230.4 0.0 3.9e-68 230.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF1730 PF08331.5 KLO15623.1 - 0.14 11.8 0.0 0.37 10.5 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1730) p450 PF00067.17 KLO15624.1 - 3.1e-53 180.9 0.0 3.6e-53 180.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 UbiA PF01040.13 KLO15626.1 - 5.9e-20 71.5 7.2 5.9e-20 71.5 5.0 1.3 2 0 0 2 2 2 1 UbiA prenyltransferase family F-box-like PF12937.2 KLO15628.1 - 8.9e-09 34.9 0.1 2.2e-08 33.6 0.1 1.7 1 0 0 1 1 1 1 F-box-like F-box-like PF12937.2 KLO15629.1 - 2.7e-08 33.3 2.1 3e-07 30.0 0.1 2.5 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 KLO15629.1 - 0.011 15.4 0.1 0.14 11.8 0.0 2.7 2 1 0 2 2 2 0 F-box domain F-box-like PF12937.2 KLO15630.1 - 3.7e-06 26.5 1.9 4e-05 23.2 0.3 2.5 2 0 0 2 2 2 1 F-box-like F-box-like PF12937.2 KLO15631.1 - 1.6e-07 30.9 0.1 6.8e-07 28.9 0.0 2.1 1 0 0 1 1 1 1 F-box-like DUF1769 PF08588.5 KLO15631.1 - 0.1 12.5 0.1 0.23 11.4 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1769) WD40 PF00400.27 KLO15632.1 - 0.071 13.0 1.9 7.7 6.5 0.0 3.5 3 0 0 3 3 3 0 WD domain, G-beta repeat PAP2_3 PF14378.1 KLO15633.1 - 1.5e-35 122.4 9.7 1.5e-35 122.4 6.7 1.7 2 0 0 2 2 2 1 PAP2 superfamily PAP2 PF01569.16 KLO15633.1 - 0.00065 19.3 3.0 0.00065 19.3 2.1 2.4 2 0 0 2 2 2 1 PAP2 superfamily PAP2_C PF14360.1 KLO15633.1 - 0.00093 19.4 2.7 0.00093 19.4 1.9 2.2 3 0 0 3 3 3 1 PAP2 superfamily C-terminal Tektin PF03148.9 KLO15636.1 - 1.2e-05 24.1 0.1 1.2e-05 24.1 0.1 1.7 2 0 0 2 2 2 1 Tektin family MscS_porin PF12795.2 KLO15636.1 - 0.0035 16.6 1.1 0.0035 16.6 0.8 2.2 2 0 0 2 2 2 1 Mechanosensitive ion channel porin domain IncA PF04156.9 KLO15636.1 - 0.0039 16.8 3.1 0.048 13.2 0.0 2.2 2 0 0 2 2 2 1 IncA protein DUF3338 PF11819.3 KLO15636.1 - 0.0087 15.5 1.9 0.051 13.0 0.0 2.5 2 1 1 3 3 3 1 Domain of unknown function (DUF3338) Cortex-I_coil PF09304.5 KLO15636.1 - 0.011 15.7 3.9 2.3 8.3 0.5 2.5 2 0 0 2 2 2 0 Cortexillin I, coiled coil EzrA PF06160.7 KLO15636.1 - 0.019 13.2 0.2 0.019 13.2 0.1 1.8 2 0 0 2 2 2 0 Septation ring formation regulator, EzrA AAA_27 PF13514.1 KLO15636.1 - 0.047 11.3 4.7 0.037 11.7 0.2 2.0 2 0 0 2 2 2 0 AAA domain GAS PF13851.1 KLO15636.1 - 0.26 10.4 5.1 0.064 12.4 0.3 2.0 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding DUF4200 PF13863.1 KLO15636.1 - 0.55 10.1 8.0 1.8 8.4 0.5 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) V_ATPase_I PF01496.14 KLO15636.1 - 0.57 7.9 3.3 0.34 8.6 0.0 1.8 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family Mito_fiss_reg PF05308.6 KLO15636.1 - 1.3 8.3 8.3 0.56 9.5 0.2 2.1 1 1 0 2 2 2 0 Mitochondrial fission regulator bZIP_1 PF00170.16 KLO15636.1 - 1.3 8.9 5.4 2.9 7.9 0.1 2.8 3 0 0 3 3 3 0 bZIP transcription factor NTR2 PF15458.1 KLO15636.1 - 1.8 7.7 7.7 4.5 6.4 4.9 1.9 1 1 1 2 2 2 0 Nineteen complex-related protein 2 CCDC155 PF14662.1 KLO15636.1 - 3 7.4 8.6 0.14 11.7 0.7 2.1 2 0 0 2 2 2 0 Coiled-coil region of CCDC155 DUF4164 PF13747.1 KLO15636.1 - 4.5 7.4 8.0 0.58 10.3 1.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4164) EMP24_GP25L PF01105.19 KLO15636.1 - 6 6.5 7.9 5.2 6.7 1.6 2.3 2 1 0 2 2 2 0 emp24/gp25L/p24 family/GOLD bZIP_2 PF07716.10 KLO15636.1 - 7.1 6.5 9.6 5.7 6.8 1.8 2.4 2 0 0 2 2 2 0 Basic region leucine zipper F-box-like PF12937.2 KLO15637.1 - 0.00015 21.4 1.4 0.00036 20.1 0.1 2.3 3 0 0 3 3 3 1 F-box-like F-box PF00646.28 KLO15637.1 - 0.074 12.7 0.2 0.74 9.5 0.1 2.8 2 1 0 2 2 2 0 F-box domain Saccharop_dh PF03435.13 KLO15638.1 - 0.14 11.0 0.0 0.19 10.6 0.0 1.1 1 0 0 1 1 1 0 Saccharopine dehydrogenase BOP1NT PF08145.7 KLO15640.1 - 5.3e-97 324.6 7.8 7.1e-97 324.1 5.4 1.2 1 0 0 1 1 1 1 BOP1NT (NUC169) domain WD40 PF00400.27 KLO15640.1 - 3e-23 80.7 11.2 6.2e-06 25.8 0.0 6.9 7 1 0 7 7 7 4 WD domain, G-beta repeat Actin PF00022.14 KLO15641.1 - 1.1e-115 386.1 0.0 1.3e-115 386.0 0.0 1.0 1 0 0 1 1 1 1 Actin MreB_Mbl PF06723.8 KLO15641.1 - 6.8e-05 21.6 0.0 0.046 12.3 0.0 2.4 2 1 0 2 2 2 2 MreB/Mbl protein DUF2423 PF10338.4 KLO15643.1 - 7.2e-13 48.2 3.4 1.6e-12 47.2 2.4 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2423) Laps PF10169.4 KLO15643.1 - 0.00068 19.8 9.7 0.00094 19.4 6.7 1.3 1 1 0 1 1 1 1 Learning-associated protein DUF2890 PF11081.3 KLO15643.1 - 0.012 15.6 3.6 0.015 15.3 2.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) DUF3335 PF11814.3 KLO15643.1 - 0.17 10.9 0.5 0.31 10.1 0.3 1.4 1 1 1 2 2 2 0 Peptidase_C39 like family DUF1985 PF09331.6 KLO15644.1 - 0.049 13.4 0.0 0.11 12.2 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1985) p450 PF00067.17 KLO15646.1 - 5e-68 229.7 0.0 6.7e-68 229.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 KLO15647.1 - 4.9e-67 226.4 0.0 6.6e-67 226.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 KLO15649.1 - 3.6e-59 200.5 0.0 4.8e-59 200.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 TauE PF01925.14 KLO15649.1 - 0.031 13.7 1.0 0.057 12.8 0.7 1.3 1 0 0 1 1 1 0 Sulfite exporter TauE/SafE Glucos_trans_II PF14264.1 KLO15649.1 - 0.25 10.3 5.1 0.4 9.6 3.5 1.3 1 0 0 1 1 1 0 Glucosyl transferase GtrII DUF3272 PF11676.3 KLO15649.1 - 4.9 7.2 5.4 21 5.2 0.9 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3272) Ribosomal_L19 PF01245.15 KLO15650.1 - 8.3e-21 73.8 0.0 1.2e-20 73.3 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L19 IMD PF08397.6 KLO15651.1 - 0.0035 16.6 2.2 0.0067 15.7 1.5 1.4 1 0 0 1 1 1 1 IRSp53/MIM homology domain ARD PF03079.9 KLO15651.1 - 0.0067 16.3 1.0 0.011 15.7 0.7 1.3 1 0 0 1 1 1 1 ARD/ARD' family DUF3150 PF11348.3 KLO15651.1 - 0.052 12.6 0.5 0.089 11.8 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3150) D5_N PF08706.6 KLO15651.1 - 0.057 13.4 0.1 0.11 12.5 0.1 1.4 1 0 0 1 1 1 0 D5 N terminal like AIP3 PF03915.8 KLO15652.1 - 0.058 12.2 0.0 0.068 12.0 0.0 1.0 1 0 0 1 1 1 0 Actin interacting protein 3 tRNA-synt_2 PF00152.15 KLO15655.1 - 4.3e-101 338.0 0.0 1.1e-55 188.7 0.0 2.3 2 1 0 2 2 2 2 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 KLO15655.1 - 1.6e-05 24.6 0.0 3.4e-05 23.6 0.0 1.6 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2b PF00587.20 KLO15655.1 - 0.0012 18.4 0.4 0.55 9.7 0.2 2.5 2 1 0 2 2 2 2 tRNA synthetase class II core domain (G, H, P, S and T) ACPS PF01648.15 KLO15657.1 - 7.5e-11 41.8 0.0 2.6e-10 40.1 0.0 1.8 2 0 0 2 2 2 1 4'-phosphopantetheinyl transferase superfamily PfkB PF00294.19 KLO15659.1 - 7e-17 61.5 0.0 7.5e-17 61.3 0.0 1.1 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Phos_pyr_kin PF08543.7 KLO15659.1 - 0.0088 15.2 0.0 0.012 14.8 0.0 1.2 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase CBFD_NFYB_HMF PF00808.18 KLO15660.1 - 3.5e-21 75.0 0.5 5.6e-21 74.3 0.4 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 KLO15660.1 - 0.00018 21.5 0.0 0.00029 20.8 0.0 1.4 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 LSM PF01423.17 KLO15661.1 - 9.8e-20 69.8 0.0 1.2e-19 69.6 0.0 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 KLO15661.1 - 0.00032 20.5 0.0 0.00041 20.1 0.0 1.2 1 0 0 1 1 1 1 Ataxin 2 SM domain RNA_POL_M_15KD PF02150.11 KLO15661.1 - 0.049 13.3 0.0 0.077 12.7 0.0 1.3 1 0 0 1 1 1 0 RNA polymerases M/15 Kd subunit DUF669 PF05037.8 KLO15661.1 - 0.066 13.1 0.0 0.1 12.4 0.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF669) RRM_1 PF00076.17 KLO15662.1 - 5.1e-15 54.8 0.0 7.6e-15 54.3 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KLO15662.1 - 7e-14 51.5 0.0 1.1e-13 50.9 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KLO15662.1 - 5.1e-07 29.4 0.0 8.3e-07 28.7 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SIR2 PF02146.12 KLO15663.1 - 1.1e-31 109.9 0.1 1e-29 103.5 0.1 3.1 1 1 0 1 1 1 1 Sir2 family TPP_enzyme_M PF00205.17 KLO15663.1 - 0.0058 16.3 0.0 0.07 12.8 0.0 2.1 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain PNTB PF02233.11 KLO15663.1 - 0.11 11.2 0.1 0.63 8.7 0.0 1.8 2 0 0 2 2 2 0 NAD(P) transhydrogenase beta subunit Fungal_trans PF04082.13 KLO15664.1 - 9.4e-31 106.6 0.0 1.4e-30 106.0 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KLO15664.1 - 3.2e-09 36.5 11.4 8.9e-09 35.1 7.9 1.8 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain IBV_3C PF03620.8 KLO15664.1 - 0.0095 15.8 0.1 0.024 14.5 0.1 1.6 1 0 0 1 1 1 1 IBV 3C protein Acyl-CoA_dh_1 PF00441.19 KLO15665.1 - 4.3e-29 101.5 1.3 6.4e-29 100.9 0.9 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 KLO15665.1 - 2.2e-15 55.8 0.1 6.8e-15 54.3 0.0 1.9 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.6 KLO15665.1 - 1.7e-12 47.7 0.8 3e-12 46.9 0.6 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 KLO15665.1 - 1.7e-10 41.5 0.0 4.5e-10 40.0 0.0 1.8 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain p450 PF00067.17 KLO15666.1 - 1.6e-67 228.0 0.0 1.9e-67 227.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF498 PF04430.9 KLO15666.1 - 0.075 12.5 0.0 0.2 11.2 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF498/DUF598) Aldedh PF00171.17 KLO15667.1 - 2.9e-85 286.3 0.0 3.5e-85 286.0 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family ACT_7 PF13840.1 KLO15667.1 - 0.12 11.8 0.0 0.28 10.7 0.0 1.6 1 0 0 1 1 1 0 ACT domain Peptidase_M24 PF00557.19 KLO15668.1 - 1.8e-14 53.8 0.0 2.4e-14 53.4 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 GTP_cyclohydro2 PF00925.15 KLO15669.1 - 1.5e-62 209.8 0.0 3.6e-57 192.2 0.0 2.1 2 0 0 2 2 2 2 GTP cyclohydrolase II Nop14 PF04147.7 KLO15671.1 - 0.013 13.4 10.1 0.019 12.9 7.0 1.1 1 0 0 1 1 1 0 Nop14-like family DUF3545 PF12065.3 KLO15671.1 - 0.11 12.2 0.4 0.25 11.1 0.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3545) DUF2457 PF10446.4 KLO15671.1 - 0.14 10.8 12.7 0.27 9.9 8.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) MIP-T3 PF10243.4 KLO15671.1 - 0.18 10.2 9.3 0.088 11.2 5.2 1.2 1 1 0 1 1 1 0 Microtubule-binding protein MIP-T3 Rep_4 PF05797.6 KLO15671.1 - 0.97 8.0 2.6 1.5 7.4 1.8 1.2 1 0 0 1 1 1 0 Yeast trans-acting factor (REP1/REP2) Peptidase_S64 PF08192.6 KLO15671.1 - 1.6 6.9 8.6 2.2 6.4 5.9 1.1 1 0 0 1 1 1 0 Peptidase family S64 Sporozoite_P67 PF05642.6 KLO15671.1 - 2.5 5.8 13.6 3.2 5.4 9.4 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen CDC45 PF02724.9 KLO15671.1 - 2.8 5.8 9.5 1.2 7.0 4.9 1.5 2 0 0 2 2 2 0 CDC45-like protein Macoilin PF09726.4 KLO15671.1 - 7.9 4.6 12.7 10 4.2 8.8 1.1 1 0 0 1 1 1 0 Transmembrane protein TFIIF_alpha PF05793.7 KLO15671.1 - 8.1 4.6 17.2 12 4.1 11.9 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Complex1_LYR_2 PF13233.1 KLO15672.1 - 4.3e-11 43.2 0.8 5.2e-11 42.9 0.5 1.1 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.10 KLO15672.1 - 0.015 15.0 1.0 0.02 14.6 0.7 1.4 1 1 0 1 1 1 0 Complex 1 protein (LYR family) DUF2265 PF10023.4 KLO15672.1 - 0.017 14.2 0.2 0.018 14.2 0.1 1.0 1 0 0 1 1 1 0 Predicted aminopeptidase (DUF2265) Complex1_LYR_1 PF13232.1 KLO15672.1 - 0.27 11.4 1.9 0.27 11.4 1.2 1.4 1 1 0 1 1 1 0 Complex1_LYR-like SIR2 PF02146.12 KLO15673.1 - 2.1e-31 109.0 0.4 5e-29 101.2 0.3 3.0 1 1 0 1 1 1 1 Sir2 family TPP_enzyme_M PF00205.17 KLO15673.1 - 0.0006 19.5 0.0 0.076 12.7 0.0 2.3 2 0 0 2 2 2 2 Thiamine pyrophosphate enzyme, central domain PNTB PF02233.11 KLO15673.1 - 0.012 14.4 0.0 0.55 8.9 0.0 2.0 2 0 0 2 2 2 0 NAD(P) transhydrogenase beta subunit MRP-S26 PF14943.1 KLO15674.1 - 0.042 13.4 0.5 0.11 12.1 0.1 1.7 1 1 1 2 2 2 0 Mitochondrial ribosome subunit S26 REV PF00424.13 KLO15674.1 - 0.083 12.7 0.1 0.15 11.9 0.1 1.4 1 0 0 1 1 1 0 REV protein (anti-repression trans-activator protein) FAD_binding_3 PF01494.14 KLO15675.1 - 1.4e-08 34.1 0.0 0.0016 17.5 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.19 KLO15675.1 - 0.02 13.8 0.0 0.027 13.3 0.0 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase RasGAP_C PF03836.10 KLO15676.1 - 3.7e-41 140.1 2.3 1.6e-40 138.0 1.6 2.2 1 0 0 1 1 1 1 RasGAP C-terminus RasGAP PF00616.14 KLO15676.1 - 1.5e-32 112.9 0.1 1.5e-32 112.9 0.1 2.0 2 0 0 2 2 2 1 GTPase-activator protein for Ras-like GTPase IQ PF00612.22 KLO15676.1 - 6.4e-19 65.7 63.8 0.00097 18.5 1.1 13.6 13 0 0 13 13 13 11 IQ calmodulin-binding motif CH PF00307.26 KLO15676.1 - 3.4e-08 33.4 0.0 1e-07 31.9 0.0 1.9 1 0 0 1 1 1 1 Calponin homology (CH) domain NPV_P10 PF05531.7 KLO15676.1 - 1.2 9.4 5.3 2.1 8.6 0.1 3.4 3 0 0 3 3 3 0 Nucleopolyhedrovirus P10 protein MFS_1 PF07690.11 KLO15677.1 - 1.6e-32 112.5 17.4 1.6e-32 112.5 12.1 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily NB PF04159.8 KLO15677.1 - 0.15 11.8 0.0 0.38 10.5 0.0 1.6 1 0 0 1 1 1 0 NB glycoprotein TFIIA PF03153.8 KLO15678.1 - 6 6.6 19.1 3.3 7.4 7.9 2.2 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit MIP-T3 PF10243.4 KLO15678.1 - 6.2 5.1 18.5 11 4.3 12.8 1.3 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 DUF605 PF04652.11 KLO15678.1 - 6.5 6.0 35.9 1.4 8.2 15.5 2.1 2 0 0 2 2 2 0 Vta1 like Peptidase_S64 PF08192.6 KLO15678.1 - 9.5 4.4 24.2 15 3.7 16.8 1.2 1 0 0 1 1 1 0 Peptidase family S64 Aldedh PF00171.17 KLO15679.1 - 1.4e-146 488.4 0.0 1.7e-146 488.2 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 KLO15679.1 - 0.00026 19.8 0.4 0.0012 17.6 0.3 1.8 1 1 0 1 1 1 1 Acyl-CoA reductase (LuxC) ComA PF02679.10 KLO15680.1 - 1.5e-71 240.2 0.0 2e-71 239.9 0.0 1.0 1 0 0 1 1 1 1 (2R)-phospho-3-sulfolactate synthase (ComA) PEP_mutase PF13714.1 KLO15680.1 - 0.023 13.9 0.0 0.037 13.2 0.0 1.3 1 0 0 1 1 1 0 Phosphoenolpyruvate phosphomutase UTP15_C PF09384.5 KLO15682.1 - 5.8e-48 162.3 0.3 9.1e-48 161.7 0.2 1.3 1 0 0 1 1 1 1 UTP15 C terminal WD40 PF00400.27 KLO15682.1 - 1.6e-31 107.0 0.5 9.4e-07 28.4 0.0 6.6 6 1 0 6 6 6 5 WD domain, G-beta repeat Cytochrom_D1 PF02239.11 KLO15682.1 - 0.00063 18.1 0.1 0.075 11.3 0.0 2.5 2 1 0 2 2 2 2 Cytochrome D1 heme domain Coatomer_WDAD PF04053.9 KLO15682.1 - 0.039 12.7 0.0 3.7 6.2 0.0 2.1 2 0 0 2 2 2 0 Coatomer WD associated region CAF1C_H4-bd PF12265.3 KLO15682.1 - 0.12 12.3 0.1 0.38 10.6 0.0 1.8 2 0 0 2 2 2 0 Histone-binding protein RBBP4 or subunit C of CAF1 complex TCTP PF00838.12 KLO15683.1 - 8.3e-61 204.7 4.4 9.3e-61 204.6 3.1 1.0 1 0 0 1 1 1 1 Translationally controlled tumour protein AlaDh_PNT_C PF01262.16 KLO15683.1 - 0.018 14.6 0.4 0.027 14.0 0.2 1.3 1 1 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain GerPC PF10737.4 KLO15683.1 - 0.019 14.7 0.3 0.024 14.4 0.2 1.2 1 0 0 1 1 1 0 Spore germination protein GerPC Ribosomal_L18_c PF14204.1 KLO15683.1 - 0.12 12.9 1.8 0.62 10.6 0.2 2.2 1 1 1 2 2 2 0 Ribosomal L18 C-terminal region Thioredoxin PF00085.15 KLO15685.1 - 3.8e-61 203.2 0.0 8e-30 102.5 0.0 3.3 3 0 0 3 3 3 2 Thioredoxin Thioredoxin_6 PF13848.1 KLO15685.1 - 9.9e-45 152.5 0.1 3.1e-33 115.1 0.0 3.4 3 1 1 4 4 4 2 Thioredoxin-like domain Thioredoxin_8 PF13905.1 KLO15685.1 - 9.8e-11 41.6 0.2 0.0034 17.4 0.0 4.2 4 0 0 4 4 4 2 Thioredoxin-like Thioredoxin_7 PF13899.1 KLO15685.1 - 3.7e-10 39.6 0.1 0.00015 21.7 0.0 2.7 2 0 0 2 2 2 2 Thioredoxin-like Thioredoxin_2 PF13098.1 KLO15685.1 - 4e-10 39.8 1.1 0.0013 18.9 0.0 4.2 3 2 0 3 3 3 2 Thioredoxin-like domain AhpC-TSA PF00578.16 KLO15685.1 - 9.5e-06 25.3 0.1 0.018 14.7 0.0 2.7 2 0 0 2 2 2 2 AhpC/TSA family Calsequestrin PF01216.12 KLO15685.1 - 3.6e-05 22.7 0.4 6.5e-05 21.8 0.2 1.4 1 0 0 1 1 1 1 Calsequestrin Thioredoxin_4 PF13462.1 KLO15685.1 - 3.9e-05 23.7 0.3 0.054 13.4 0.0 2.8 3 0 0 3 3 3 2 Thioredoxin Redoxin PF08534.5 KLO15685.1 - 5.9e-05 22.6 0.5 0.16 11.5 0.1 3.2 3 0 0 3 3 3 2 Redoxin Thioredoxin_3 PF13192.1 KLO15685.1 - 0.0042 16.8 0.0 0.22 11.3 0.0 2.4 2 0 0 2 2 2 1 Thioredoxin domain Glutaredoxin PF00462.19 KLO15685.1 - 0.29 11.1 1.9 15 5.6 0.0 3.0 2 1 0 2 2 2 0 Glutaredoxin WH2 PF02205.15 KLO15686.1 - 2.7e-07 29.9 0.8 5.6e-07 28.9 0.5 1.5 1 0 0 1 1 1 1 WH2 motif FAT PF02259.18 KLO15687.1 - 7.2e-69 232.4 4.0 2e-68 230.9 2.7 1.8 1 0 0 1 1 1 1 FAT domain PI3_PI4_kinase PF00454.22 KLO15687.1 - 4.9e-14 52.3 0.1 1.5e-13 50.7 0.1 1.9 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase TPR_2 PF07719.12 KLO15687.1 - 4e-05 23.2 0.9 0.17 11.8 0.1 3.5 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.1 KLO15687.1 - 0.0016 18.3 7.0 0.19 11.6 0.0 4.7 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_8 PF13181.1 KLO15687.1 - 0.002 17.7 2.1 0.047 13.4 0.1 3.1 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.23 KLO15687.1 - 0.0025 17.3 1.7 0.23 11.1 0.1 3.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_11 PF13414.1 KLO15687.1 - 0.01 15.4 2.8 0.13 11.8 0.1 3.4 3 0 0 3 3 3 1 TPR repeat FATC PF02260.15 KLO15687.1 - 0.011 15.1 0.1 0.03 13.7 0.1 1.8 1 0 0 1 1 1 0 FATC domain AA_permease_2 PF13520.1 KLO15688.1 - 1.9e-58 198.0 57.3 2.4e-58 197.6 39.7 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 KLO15688.1 - 2.3e-16 59.2 51.6 3.3e-16 58.7 35.8 1.1 1 0 0 1 1 1 1 Amino acid permease Bromodomain PF00439.20 KLO15689.1 - 3e-22 78.3 0.2 6.6e-22 77.2 0.2 1.6 1 0 0 1 1 1 1 Bromodomain DUF3336 PF11815.3 KLO15690.1 - 5.4e-43 145.9 3.5 9.3e-43 145.2 0.5 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF3336) Patatin PF01734.17 KLO15690.1 - 6.5e-21 75.1 0.1 1.2e-20 74.3 0.1 1.5 1 0 0 1 1 1 1 Patatin-like phospholipase DUF262 PF03235.9 KLO15691.1 - 4.9e-16 59.3 2.6 1.5e-15 57.8 0.3 2.5 2 1 0 2 2 2 1 Protein of unknown function DUF262 Asp PF00026.18 KLO15692.1 - 5.5e-96 321.5 0.0 6.8e-96 321.2 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 KLO15692.1 - 1.6e-09 37.9 0.2 3.4e-09 36.8 0.1 1.6 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 KLO15692.1 - 2.3e-07 31.2 0.0 0.00067 20.1 0.0 2.7 2 1 0 2 2 2 2 Aspartyl protease TAXi_C PF14541.1 KLO15692.1 - 0.00014 21.4 0.0 0.00055 19.5 0.0 2.0 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal Asp PF00026.18 KLO15693.1 - 1.7e-107 359.3 0.0 2e-107 359.0 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 KLO15693.1 - 1.2e-09 38.3 0.0 2.2e-09 37.4 0.0 1.5 1 0 0 1 1 1 1 Xylanase inhibitor N-terminal TAXi_C PF14541.1 KLO15693.1 - 2.6e-05 23.7 0.0 0.00051 19.6 0.0 2.5 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal Asp_protease_2 PF13650.1 KLO15693.1 - 3.2e-05 24.3 0.0 0.046 14.2 0.0 2.7 2 0 0 2 2 2 2 Aspartyl protease PUB PF09409.5 KLO15695.1 - 8.5e-10 38.2 0.5 4.1e-09 36.0 0.0 2.2 2 0 0 2 2 2 1 PUB domain Cwf_Cwc_15 PF04889.7 KLO15695.1 - 0.37 10.4 14.8 0.39 10.3 7.3 2.2 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein TRAP-gamma PF07074.7 KLO15695.1 - 0.86 9.1 3.2 1.4 8.4 2.2 1.3 1 0 0 1 1 1 0 Translocon-associated protein, gamma subunit (TRAP-gamma) Proteasome PF00227.21 KLO15696.1 - 6.9e-48 162.4 0.0 5.5e-46 156.2 0.0 2.1 1 1 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 KLO15696.1 - 4.5e-13 48.2 0.0 4.5e-13 48.2 0.0 1.9 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature Flavokinase PF01687.12 KLO15696.1 - 0.043 13.7 0.0 0.07 13.0 0.0 1.4 1 0 0 1 1 1 0 Riboflavin kinase SMC_N PF02463.14 KLO15697.1 - 3.4e-26 91.8 0.0 3.6e-26 91.7 0.0 1.1 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 KLO15697.1 - 8.6e-07 29.2 0.5 1.5e-06 28.4 0.3 1.5 1 1 0 1 1 1 1 AAA domain ABC_tran PF00005.22 KLO15697.1 - 0.021 15.1 0.0 0.032 14.5 0.0 1.4 1 0 0 1 1 1 0 ABC transporter WD40 PF00400.27 KLO15698.1 - 1.7e-22 78.3 3.9 3.1e-09 36.3 0.1 5.3 5 0 0 5 5 5 4 WD domain, G-beta repeat Pkinase PF00069.20 KLO15699.1 - 1.8e-71 240.3 0.0 2.1e-71 240.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KLO15699.1 - 1.9e-35 122.1 0.0 2.3e-35 121.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KLO15699.1 - 6.6e-08 31.8 0.2 2.4e-06 26.7 0.0 2.4 1 1 2 3 3 3 1 Kinase-like Kdo PF06293.9 KLO15699.1 - 0.0017 17.4 0.4 0.0043 16.1 0.3 1.7 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family PCI PF01399.22 KLO15700.1 - 4.9e-10 39.6 0.0 2.6e-09 37.3 0.0 2.3 2 0 0 2 2 2 1 PCI domain TAFH PF07531.9 KLO15700.1 - 0.065 12.8 2.5 1.2 8.8 0.3 3.0 2 1 1 3 3 3 0 NHR1 homology to TAF Flavin_Reduct PF01613.13 KLO15701.1 - 1.1e-23 83.8 0.1 1.6e-23 83.2 0.1 1.1 1 0 0 1 1 1 1 Flavin reductase like domain Pyridox_oxidase PF01243.15 KLO15701.1 - 0.074 13.0 0.0 0.13 12.3 0.0 1.4 1 0 0 1 1 1 0 Pyridoxamine 5'-phosphate oxidase ABC_tran PF00005.22 KLO15702.1 - 7e-22 78.1 0.0 1.5e-21 77.1 0.0 1.6 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 KLO15702.1 - 1.2e-10 41.8 0.0 1.5e-05 25.0 0.0 2.3 2 0 0 2 2 2 2 AAA domain SMC_N PF02463.14 KLO15702.1 - 4.3e-07 29.4 0.0 5.1e-06 25.8 0.0 2.2 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_15 PF13175.1 KLO15702.1 - 1.8e-05 24.0 0.0 0.0013 17.8 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 KLO15702.1 - 0.00073 19.6 0.0 0.41 10.8 0.0 3.3 3 0 0 3 3 3 1 AAA domain AAA_13 PF13166.1 KLO15702.1 - 0.0017 16.9 0.0 0.4 9.0 0.0 2.1 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.1 KLO15702.1 - 0.0031 17.0 0.0 0.0071 15.8 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain DUF258 PF03193.11 KLO15702.1 - 0.0078 15.4 0.0 0.014 14.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 SbcCD_C PF13558.1 KLO15702.1 - 0.0093 15.8 0.1 0.036 13.9 0.0 2.0 1 1 0 1 1 1 1 Putative exonuclease SbcCD, C subunit MMR_HSR1 PF01926.18 KLO15702.1 - 0.02 14.8 0.0 0.084 12.8 0.0 1.9 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_33 PF13671.1 KLO15702.1 - 0.022 14.6 0.0 0.061 13.2 0.0 1.8 2 0 0 2 2 1 0 AAA domain AAA_17 PF13207.1 KLO15702.1 - 0.034 14.9 0.0 0.075 13.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.1 KLO15702.1 - 0.036 14.0 0.0 0.12 12.3 0.0 1.9 2 0 0 2 2 2 0 AAA ATPase domain AAA_23 PF13476.1 KLO15702.1 - 0.036 14.3 0.0 0.063 13.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain MobB PF03205.9 KLO15702.1 - 0.051 13.2 0.0 0.11 12.2 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_10 PF12846.2 KLO15702.1 - 0.11 11.9 0.2 1.2 8.5 0.1 2.5 2 1 0 3 3 3 0 AAA-like domain GTP_cyclohydroI PF01227.17 KLO15703.1 - 3.4e-74 247.9 0.1 4.2e-74 247.6 0.0 1.1 1 0 0 1 1 1 1 GTP cyclohydrolase I QueF PF14489.1 KLO15703.1 - 0.00011 22.0 0.0 0.00025 20.9 0.0 1.6 2 0 0 2 2 2 1 QueF-like protein HATPase_c_2 PF13581.1 KLO15703.1 - 0.065 13.0 0.5 0.2 11.4 0.1 1.9 2 0 0 2 2 2 0 Histidine kinase-like ATPase domain Tho2 PF11262.3 KLO15704.1 - 9.6e-57 192.2 0.0 1.7e-56 191.4 0.0 1.4 1 0 0 1 1 1 1 Transcription factor/nuclear export subunit protein 2 Thoc2 PF11732.3 KLO15704.1 - 1.2e-26 92.3 0.0 2.5e-26 91.2 0.0 1.6 1 0 0 1 1 1 1 Transcription- and export-related complex subunit DUF2458 PF10454.4 KLO15705.1 - 1.8e-11 44.1 0.4 2.8e-11 43.5 0.3 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2458) Ribosomal_L3 PF00297.17 KLO15706.1 - 1.6e-120 401.4 8.1 1.9e-120 401.1 5.6 1.1 1 0 0 1 1 1 1 Ribosomal protein L3 PPR_2 PF13041.1 KLO15711.1 - 3.1e-12 46.2 0.0 5.3e-06 26.3 0.0 3.8 3 0 0 3 3 3 3 PPR repeat family PPR_1 PF12854.2 KLO15711.1 - 2.4e-08 33.3 0.1 0.00016 21.0 0.0 3.2 3 0 0 3 3 3 2 PPR repeat PPR PF01535.15 KLO15711.1 - 1.1e-07 31.3 0.2 0.00055 19.7 0.0 4.6 5 0 0 5 5 5 1 PPR repeat PPR_3 PF13812.1 KLO15711.1 - 1.6e-07 31.0 1.2 0.43 10.9 0.0 5.4 6 0 0 6 6 6 2 Pentatricopeptide repeat domain AMMECR1 PF01871.12 KLO15712.1 - 2.8e-41 140.4 0.0 1.3e-28 99.2 0.0 2.4 3 0 0 3 3 3 2 AMMECR1 Ras PF00071.17 KLO15713.1 - 5.7e-47 159.1 0.0 5.5e-43 146.1 0.0 2.1 2 0 0 2 2 2 2 Ras family Miro PF08477.8 KLO15713.1 - 6.1e-21 75.1 0.0 1.1e-20 74.2 0.0 1.5 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KLO15713.1 - 2e-11 43.4 0.1 3.8e-11 42.5 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 KLO15713.1 - 1.1e-06 28.6 0.0 1.9e-06 27.7 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 KLO15713.1 - 8.8e-05 21.7 0.0 0.00013 21.1 0.0 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.5 KLO15713.1 - 0.00093 18.4 1.2 0.0042 16.3 0.0 2.3 2 1 1 3 3 3 1 Signal recognition particle receptor beta subunit AAA_22 PF13401.1 KLO15713.1 - 0.0012 19.0 0.1 0.0038 17.3 0.0 1.9 2 1 0 2 2 1 1 AAA domain PduV-EutP PF10662.4 KLO15713.1 - 0.0013 18.2 0.1 0.0094 15.4 0.1 2.1 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation Arch_ATPase PF01637.13 KLO15713.1 - 0.002 17.8 0.0 0.0039 16.9 0.0 1.4 1 0 0 1 1 1 1 Archaeal ATPase GTP_EFTU PF00009.22 KLO15713.1 - 0.014 14.8 0.0 0.38 10.1 0.0 2.7 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain DUF258 PF03193.11 KLO15713.1 - 0.016 14.4 0.0 0.036 13.2 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_14 PF13173.1 KLO15713.1 - 0.018 14.9 0.1 0.047 13.5 0.1 1.6 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.1 KLO15713.1 - 0.06 13.3 0.1 0.22 11.5 0.0 2.0 2 1 0 2 2 2 0 AAA ATPase domain Dynamin_N PF00350.18 KLO15713.1 - 0.064 13.0 0.5 0.18 11.6 0.1 1.9 2 1 0 2 2 2 0 Dynamin family Septin PF00735.13 KLO15713.1 - 0.11 11.4 0.1 0.22 10.5 0.1 1.4 1 0 0 1 1 1 0 Septin Ribosomal_L2_C PF03947.13 KLO15715.1 - 1.3e-41 141.4 1.3 2.4e-41 140.5 0.9 1.4 1 0 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.18 KLO15715.1 - 9.9e-15 54.2 0.1 2.2e-14 53.1 0.1 1.6 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain Med26 PF08711.6 KLO15716.1 - 5.2e-08 32.2 0.0 1.1e-07 31.2 0.0 1.6 1 0 0 1 1 1 1 TFIIS helical bundle-like domain zf-CCCH PF00642.19 KLO15716.1 - 6.4e-07 28.9 2.8 1.2e-06 28.0 2.0 1.5 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) HMG_box PF00505.14 KLO15717.1 - 8.4e-16 57.9 1.0 8.4e-16 57.9 0.7 2.0 2 0 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.5 KLO15717.1 - 1.8e-13 50.6 0.7 1.8e-13 50.6 0.5 2.3 2 0 0 2 2 2 1 HMG-box domain Abhydrolase_5 PF12695.2 KLO15718.1 - 9.7e-09 35.1 0.0 1.3e-08 34.7 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KLO15718.1 - 2e-07 31.1 0.0 2.2e-06 27.7 0.0 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 KLO15718.1 - 1.3e-05 24.5 0.0 4.6e-05 22.7 0.0 1.8 1 1 0 1 1 1 1 Prolyl oligopeptidase family DUF2048 PF09752.4 KLO15718.1 - 0.00046 19.1 0.1 0.00072 18.5 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2048) PhoPQ_related PF10142.4 KLO15718.1 - 0.016 13.7 0.0 0.029 12.8 0.0 1.5 2 0 0 2 2 2 0 PhoPQ-activated pathogenicity-related protein DLH PF01738.13 KLO15718.1 - 0.039 13.2 0.0 0.48 9.6 0.0 2.0 1 1 0 1 1 1 0 Dienelactone hydrolase family Abhydrolase_3 PF07859.8 KLO15718.1 - 0.1 12.1 0.0 0.21 11.1 0.0 1.6 2 0 0 2 2 2 0 alpha/beta hydrolase fold WW PF00397.21 KLO15719.1 - 6.6e-07 29.0 3.8 1.9e-06 27.5 2.6 1.9 1 0 0 1 1 1 1 WW domain NACHT PF05729.7 KLO15720.1 - 1e-08 35.0 0.0 2.3e-08 33.8 0.0 1.6 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.1 KLO15720.1 - 1.1e-05 25.5 0.0 2.7e-05 24.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 KLO15720.1 - 2e-05 24.6 0.0 7e-05 22.8 0.0 2.0 1 0 0 1 1 1 1 AAA ATPase domain WD40 PF00400.27 KLO15720.1 - 0.00034 20.3 4.6 12 5.9 0.2 6.2 7 0 0 7 7 7 1 WD domain, G-beta repeat NB-ARC PF00931.17 KLO15720.1 - 0.00072 18.5 0.0 0.0016 17.3 0.0 1.6 1 0 0 1 1 1 1 NB-ARC domain PD40 PF07676.7 KLO15720.1 - 0.0037 16.8 0.0 0.35 10.5 0.0 3.6 3 0 0 3 3 3 1 WD40-like Beta Propeller Repeat AAA PF00004.24 KLO15720.1 - 0.0042 17.2 0.0 0.012 15.8 0.0 1.8 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) KAP_NTPase PF07693.9 KLO15720.1 - 0.0078 15.2 0.1 0.013 14.4 0.1 1.4 1 0 0 1 1 1 1 KAP family P-loop domain Arch_ATPase PF01637.13 KLO15720.1 - 0.022 14.4 0.0 0.04 13.6 0.0 1.3 1 0 0 1 1 1 0 Archaeal ATPase AAA_17 PF13207.1 KLO15720.1 - 0.052 14.3 0.2 0.6 10.9 0.0 2.9 3 0 0 3 3 3 0 AAA domain Parvo_NS1 PF01057.12 KLO15720.1 - 0.076 11.8 0.1 0.14 11.0 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Activator-TraM PF11657.3 KLO15720.1 - 0.15 11.5 0.1 0.35 10.3 0.1 1.6 1 0 0 1 1 1 0 Transcriptional activator TraM DUF4259 PF14078.1 KLO15721.1 - 0.048 14.1 0.1 0.073 13.5 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4259) DUF935 PF06074.7 KLO15721.1 - 0.079 11.6 0.1 0.11 11.1 0.1 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF935) PilJ PF13675.1 KLO15721.1 - 0.081 13.2 0.0 0.17 12.2 0.0 1.6 1 1 0 1 1 1 0 Type IV pili methyl-accepting chemotaxis transducer N-term NACHT PF05729.7 KLO15722.1 - 6e-09 35.7 0.0 1.1e-08 34.8 0.0 1.5 1 0 0 1 1 1 1 NACHT domain WD40 PF00400.27 KLO15722.1 - 1.2e-07 31.3 6.9 0.00096 18.9 0.2 6.6 7 0 0 7 7 7 1 WD domain, G-beta repeat eIF2A PF08662.6 KLO15722.1 - 1.9e-07 31.0 0.0 0.0058 16.3 0.0 2.5 2 0 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A AAA_22 PF13401.1 KLO15722.1 - 1.1e-05 25.6 0.0 2.9e-05 24.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 KLO15722.1 - 9.7e-05 22.4 0.0 0.00051 20.0 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain NB-ARC PF00931.17 KLO15722.1 - 0.001 18.0 0.1 0.0019 17.1 0.0 1.4 1 0 0 1 1 1 1 NB-ARC domain Arch_ATPase PF01637.13 KLO15722.1 - 0.014 15.0 0.0 0.026 14.2 0.0 1.4 1 0 0 1 1 1 0 Archaeal ATPase AAA PF00004.24 KLO15722.1 - 0.022 14.9 0.0 0.058 13.6 0.0 1.8 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) APS_kinase PF01583.15 KLO15722.1 - 0.073 12.7 0.0 0.13 11.8 0.0 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase KAP_NTPase PF07693.9 KLO15722.1 - 0.1 11.5 0.1 0.16 10.9 0.0 1.2 1 0 0 1 1 1 0 KAP family P-loop domain Parvo_NS1 PF01057.12 KLO15722.1 - 0.13 11.0 0.1 0.27 10.0 0.0 1.4 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_19 PF13245.1 KLO15722.1 - 0.15 11.8 0.0 0.55 10.0 0.0 1.9 1 0 0 1 1 1 0 Part of AAA domain AAA_30 PF13604.1 KLO15722.1 - 0.33 10.5 0.2 1.2 8.7 0.0 1.9 2 0 0 2 2 2 0 AAA domain SNF2_N PF00176.18 KLO15723.1 - 1.8e-60 204.2 0.0 2.6e-60 203.7 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 KLO15723.1 - 3.9e-11 42.6 0.0 9.9e-11 41.3 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 KLO15723.1 - 1.1e-06 28.2 0.0 3.7e-06 26.5 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase zf-RING_2 PF13639.1 KLO15723.1 - 2.7e-06 27.0 4.1 2.7e-06 27.0 2.8 2.3 2 1 0 2 2 1 1 Ring finger domain ResIII PF04851.10 KLO15723.1 - 3.3e-06 27.0 0.0 6.1e-06 26.1 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit zf-C3HC4 PF00097.20 KLO15723.1 - 2e-05 24.1 6.0 2e-05 24.1 4.1 2.6 2 1 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KLO15723.1 - 8e-05 22.5 5.1 8e-05 22.5 3.5 3.0 2 1 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-Nse PF11789.3 KLO15723.1 - 0.00057 19.3 3.3 0.0014 18.0 2.3 1.7 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-C3HC4_3 PF13920.1 KLO15723.1 - 0.0011 18.5 3.2 0.0011 18.5 2.2 2.3 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 KLO15723.1 - 0.0012 18.6 4.4 0.0012 18.6 3.0 2.2 2 0 0 2 2 1 1 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.2 KLO15723.1 - 0.0014 18.7 0.7 0.0039 17.2 0.5 1.8 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_6 PF14835.1 KLO15723.1 - 0.0033 17.1 1.3 0.008 15.9 0.9 1.6 1 0 0 1 1 1 1 zf-RING of BARD1-type protein DEAD_2 PF06733.10 KLO15723.1 - 0.022 14.1 0.1 0.022 14.1 0.1 2.5 2 1 0 2 2 2 0 DEAD_2 AAA_34 PF13872.1 KLO15723.1 - 0.032 12.9 0.0 0.09 11.5 0.1 1.7 2 0 0 2 2 2 0 P-loop containing NTP hydrolase pore-1 Helicase_C_4 PF13871.1 KLO15723.1 - 0.093 12.1 0.2 0.34 10.2 0.0 1.8 2 0 0 2 2 2 0 Helicase_C-like Maf_N PF08383.6 KLO15723.1 - 0.15 11.6 0.4 8.2 6.0 0.1 3.4 4 0 0 4 4 4 0 Maf N-terminal region WD40 PF00400.27 KLO15725.1 - 4e-16 58.1 3.5 0.00013 21.6 0.0 5.6 6 0 0 6 6 6 4 WD domain, G-beta repeat SH3_9 PF14604.1 KLO15726.1 - 1.5e-07 30.8 0.2 0.013 15.0 0.1 2.4 2 0 0 2 2 2 2 Variant SH3 domain SH3_1 PF00018.23 KLO15726.1 - 3.1e-06 26.4 0.4 9.5e-05 21.7 0.1 2.3 2 0 0 2 2 2 1 SH3 domain SH3_2 PF07653.12 KLO15726.1 - 0.00066 19.1 0.2 0.0074 15.7 0.2 2.1 1 1 0 1 1 1 1 Variant SH3 domain Cyclin_N PF00134.18 KLO15727.1 - 3.5e-15 55.6 0.1 1.2e-14 53.9 0.0 1.8 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin PF08613.6 KLO15727.1 - 4.7e-12 46.5 0.0 5.8e-12 46.2 0.0 1.2 1 0 0 1 1 1 1 Cyclin Zn_clus PF00172.13 KLO15728.1 - 4.6 7.2 9.2 4.1 7.3 0.6 2.3 2 0 0 2 2 2 0 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-FPG_IleRS PF06827.9 KLO15729.1 - 0.012 15.1 3.1 4.1 7.1 0.0 3.3 3 0 0 3 3 3 0 Zinc finger found in FPG and IleRS LIM_bind PF01803.11 KLO15730.1 - 6.9e-41 139.9 0.0 1.4e-37 129.1 0.0 2.0 1 1 1 2 2 2 2 LIM-domain binding protein S4 PF01479.20 KLO15732.1 - 2.1e-11 43.0 0.0 3.6e-11 42.3 0.0 1.4 1 0 0 1 1 1 1 S4 domain Ribosomal_S4 PF00163.14 KLO15732.1 - 1.1e-10 41.7 0.2 1.6e-10 41.2 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain DUF4139 PF13598.1 KLO15733.1 - 6.4e-68 229.3 1.6 6.4e-68 229.3 1.1 2.7 2 1 0 2 2 2 1 Domain of unknown function (DUF4139) DUF4140 PF13600.1 KLO15733.1 - 2.7e-14 53.4 4.2 6.3e-13 49.0 0.0 3.2 3 0 0 3 3 3 1 N-terminal domain of unknown function (DUF4140) Baculo_PEP_C PF04513.7 KLO15733.1 - 0.0026 17.6 0.8 0.0054 16.5 0.6 1.5 1 0 0 1 1 1 1 Baculovirus polyhedron envelope protein, PEP, C terminus CARDB PF07705.6 KLO15733.1 - 0.022 14.7 0.0 15 5.6 0.0 3.1 2 0 0 2 2 2 0 CARDB DUF4139 PF13598.1 KLO15734.1 - 1.1e-74 251.5 5.5 2.9e-74 250.2 3.8 1.7 1 1 0 1 1 1 1 Domain of unknown function (DUF4139) DUF4140 PF13600.1 KLO15734.1 - 1.1e-16 61.1 4.1 1.3e-15 57.6 0.0 3.3 2 1 1 3 3 3 1 N-terminal domain of unknown function (DUF4140) adh_short PF00106.20 KLO15735.1 - 1.5e-22 80.3 2.1 1.9e-22 79.9 1.5 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KLO15735.1 - 5e-21 75.5 0.1 6.1e-21 75.2 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KLO15735.1 - 1.2e-06 28.3 0.1 2e-06 27.6 0.1 1.3 1 0 0 1 1 1 1 KR domain 3HCDH_N PF02737.13 KLO15735.1 - 0.0043 16.7 0.5 0.0086 15.7 0.4 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Eno-Rase_NADH_b PF12242.3 KLO15735.1 - 0.011 15.4 0.6 0.03 14.0 0.4 1.7 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Hex_IIIa PF02455.11 KLO15736.1 - 6.5 5.3 6.4 1.1 7.9 1.5 1.6 1 1 0 1 1 1 0 Hexon-associated protein (IIIa) RRM_6 PF14259.1 KLO15737.1 - 8.4e-07 28.8 0.0 4.7e-06 26.4 0.0 2.2 2 1 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 KLO15737.1 - 0.0011 18.6 0.0 0.16 11.6 0.0 2.4 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KLO15737.1 - 0.012 15.3 0.0 0.055 13.3 0.0 2.1 1 1 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF3546 PF12066.3 KLO15738.1 - 1.1e-15 57.5 0.7 3.4e-15 56.0 0.2 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF3546) ARS2 PF04959.8 KLO15738.1 - 8.2e-13 49.0 0.3 8.2e-13 49.0 0.2 2.8 2 1 0 2 2 2 1 Arsenite-resistance protein 2 DUF4187 PF13821.1 KLO15738.1 - 1.7e-05 24.3 0.8 4.2e-05 23.0 0.5 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4187) zf-C2H2_2 PF12756.2 KLO15738.1 - 0.094 12.8 0.7 4.9 7.3 0.0 2.4 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-BED PF02892.10 KLO15738.1 - 0.16 11.7 1.4 0.25 11.1 0.1 1.9 2 0 0 2 2 2 0 BED zinc finger zf-C2H2 PF00096.21 KLO15738.1 - 0.65 10.4 5.0 0.34 11.3 0.8 2.5 2 0 0 2 2 2 0 Zinc finger, C2H2 type Nuf2 PF03800.9 KLO15739.1 - 1.1e-32 113.0 2.5 1.5e-32 112.6 0.0 2.3 2 1 0 2 2 2 1 Nuf2 family GAS PF13851.1 KLO15739.1 - 0.0079 15.4 49.2 0.07 12.3 5.5 3.2 2 1 1 3 3 3 3 Growth-arrest specific micro-tubule binding DUF812 PF05667.6 KLO15739.1 - 0.54 8.7 39.8 3.3 6.1 27.5 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF812) ERM PF00769.14 KLO15739.1 - 1.1 8.7 43.6 0.021 14.4 8.7 2.5 1 1 1 2 2 2 0 Ezrin/radixin/moesin family Sec34 PF04136.10 KLO15739.1 - 2.9 7.5 22.1 1 9.0 1.3 3.7 2 1 0 3 3 3 0 Sec34-like family AA_kinase PF00696.23 KLO15740.1 - 2.1e-40 138.8 1.5 3.3e-40 138.1 1.0 1.2 1 0 0 1 1 1 1 Amino acid kinase family PUA PF01472.15 KLO15740.1 - 4e-12 45.6 0.4 3.1e-05 23.6 0.1 2.7 3 0 0 3 3 3 2 PUA domain DUF2414 PF10309.4 KLO15742.1 - 1.5e-06 27.8 0.0 2.9e-06 26.8 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2414) FoP_duplication PF13865.1 KLO15742.1 - 7.7e-05 23.0 10.1 7.7e-05 23.0 7.0 3.1 2 1 0 2 2 2 1 C-terminal duplication domain of Friend of PRMT1 KH_1 PF00013.24 KLO15743.1 - 4.7e-05 22.9 0.0 0.00011 21.7 0.0 1.6 1 0 0 1 1 1 1 KH domain KH_3 PF13014.1 KLO15743.1 - 0.0016 18.0 0.0 0.0039 16.8 0.0 1.7 1 0 0 1 1 1 1 KH domain KH_4 PF13083.1 KLO15743.1 - 0.011 15.3 0.7 0.033 13.8 0.0 2.2 2 0 0 2 2 2 0 KH domain Methyltransf_11 PF08241.7 KLO15744.1 - 9.8e-15 54.8 0.0 1.7e-14 54.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KLO15744.1 - 9.3e-09 35.6 0.0 1.8e-08 34.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KLO15744.1 - 4.7e-07 29.5 0.0 5.9e-07 29.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KLO15744.1 - 4.8e-07 29.6 0.0 8.1e-07 28.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KLO15744.1 - 2.6e-06 27.9 0.0 5.6e-06 26.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KLO15744.1 - 8.8e-05 22.8 0.0 0.00018 21.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KLO15744.1 - 0.00013 22.0 0.0 0.0004 20.4 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.13 KLO15744.1 - 0.011 14.8 0.0 0.016 14.3 0.0 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family RrnaAD PF00398.15 KLO15744.1 - 0.13 11.2 0.0 0.2 10.6 0.0 1.5 1 1 0 1 1 1 0 Ribosomal RNA adenine dimethylase Arrestin_N PF00339.24 KLO15745.1 - 4.6e-06 26.5 0.6 0.00053 19.8 0.0 3.1 3 1 0 3 3 3 2 Arrestin (or S-antigen), N-terminal domain ACBP PF00887.14 KLO15746.1 - 1.3e-24 85.6 0.1 2.3e-24 84.8 0.1 1.4 1 0 0 1 1 1 1 Acyl CoA binding protein DUF605 PF04652.11 KLO15746.1 - 0.92 8.8 16.0 1.3 8.3 11.1 1.3 1 0 0 1 1 1 0 Vta1 like zf-MYND PF01753.13 KLO15748.1 - 7.7e-05 22.4 14.3 0.00014 21.6 9.9 1.4 1 0 0 1 1 1 1 MYND finger APH PF01636.18 KLO15748.1 - 0.12 12.1 0.1 0.21 11.2 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Vfa1 PF08432.5 KLO15749.1 - 1.2e-37 129.7 6.2 1.5e-37 129.4 4.3 1.0 1 0 0 1 1 1 1 AAA-ATPase Vps4-associated protein 1 Atrophin-1 PF03154.10 KLO15749.1 - 1.6e-05 23.3 4.3 2e-05 22.9 3.0 1.2 1 0 0 1 1 1 1 Atrophin-1 family Ycf1 PF05758.7 KLO15749.1 - 0.00063 17.6 2.9 0.00067 17.5 2.0 1.0 1 0 0 1 1 1 1 Ycf1 U79_P34 PF03064.11 KLO15749.1 - 0.00097 18.7 10.7 0.0012 18.4 7.4 1.2 1 0 0 1 1 1 1 HSV U79 / HCMV P34 Pex14_N PF04695.8 KLO15749.1 - 0.016 15.2 2.8 0.025 14.6 2.0 1.4 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region eIF3_subunit PF08597.5 KLO15749.1 - 0.018 14.6 16.7 0.021 14.4 11.6 1.2 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit MIP-T3 PF10243.4 KLO15749.1 - 0.026 13.0 19.8 0.029 12.8 13.7 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Tim54 PF11711.3 KLO15749.1 - 0.033 12.7 6.5 0.038 12.6 4.5 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 FLO_LFY PF01698.11 KLO15749.1 - 0.046 12.5 6.6 0.061 12.1 4.6 1.1 1 0 0 1 1 1 0 Floricaula / Leafy protein NARP1 PF12569.3 KLO15749.1 - 0.052 12.2 12.5 0.069 11.9 8.7 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 GAGA_bind PF06217.7 KLO15749.1 - 0.053 13.4 4.5 0.066 13.1 3.1 1.2 1 0 0 1 1 1 0 GAGA binding protein-like family Rtf2 PF04641.7 KLO15749.1 - 0.057 12.6 11.1 0.074 12.2 7.7 1.2 1 0 0 1 1 1 0 Rtf2 RING-finger HTH_29 PF13551.1 KLO15749.1 - 0.082 13.0 1.1 0.11 12.6 0.1 1.7 2 0 0 2 2 2 0 Winged helix-turn helix DUF3987 PF13148.1 KLO15749.1 - 0.093 11.2 10.3 0.13 10.7 7.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) Borrelia_P83 PF05262.6 KLO15749.1 - 0.11 10.7 13.0 0.13 10.5 9.0 1.0 1 0 0 1 1 1 0 Borrelia P83/100 protein BSMAP PF12280.3 KLO15749.1 - 0.25 11.2 3.2 0.34 10.7 2.2 1.2 1 0 0 1 1 1 0 Brain specific membrane anchored protein DUF1510 PF07423.6 KLO15749.1 - 0.25 10.6 17.6 0.34 10.2 12.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) DDHD PF02862.12 KLO15749.1 - 0.25 11.0 4.5 0.35 10.6 3.1 1.3 1 0 0 1 1 1 0 DDHD domain DUF2201_N PF13203.1 KLO15749.1 - 0.29 10.2 7.2 0.37 9.9 5.0 1.1 1 0 0 1 1 1 0 Putative metallopeptidase domain Hid1 PF12722.2 KLO15749.1 - 0.35 8.4 4.7 0.38 8.3 3.3 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF4407 PF14362.1 KLO15749.1 - 0.44 9.4 2.0 0.49 9.2 1.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) SAPS PF04499.10 KLO15749.1 - 0.51 8.9 5.0 0.57 8.7 3.4 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein CDC45 PF02724.9 KLO15749.1 - 0.66 7.9 13.3 0.8 7.6 9.2 1.0 1 0 0 1 1 1 0 CDC45-like protein DUF3449 PF11931.3 KLO15749.1 - 0.82 9.1 10.5 1.5 8.2 7.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3449) RRN3 PF05327.6 KLO15749.1 - 1 7.3 6.4 1.2 7.2 4.4 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 YqfQ PF14181.1 KLO15749.1 - 1.6 8.7 15.6 2.3 8.2 10.8 1.2 1 0 0 1 1 1 0 YqfQ-like protein RR_TM4-6 PF06459.7 KLO15749.1 - 1.9 8.3 13.5 2.5 7.9 9.4 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 SelP_N PF04592.9 KLO15749.1 - 4.7 6.5 7.6 6.2 6.1 5.3 1.2 1 0 0 1 1 1 0 Selenoprotein P, N terminal region TSA PF03249.8 KLO15749.1 - 5.8 5.3 6.4 8.2 4.8 4.5 1.1 1 0 0 1 1 1 0 Type specific antigen DUF3513 PF12026.3 KLO15749.1 - 6.5 6.2 9.2 9.1 5.7 6.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3513) ADH_N PF08240.7 KLO15750.1 - 5e-26 90.5 2.3 1.4e-25 89.1 1.6 1.8 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KLO15750.1 - 4.1e-19 68.4 0.1 6.9e-19 67.6 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 KLO15750.1 - 0.0059 15.7 0.0 0.01 15.0 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ThiF PF00899.16 KLO15750.1 - 0.031 14.0 0.3 0.38 10.5 0.3 2.2 2 0 0 2 2 2 0 ThiF family F-box-like PF12937.2 KLO15751.1 - 3.8e-07 29.7 0.5 9e-07 28.5 0.4 1.7 1 0 0 1 1 1 1 F-box-like F-box-like_2 PF13013.1 KLO15751.1 - 0.091 12.4 0.0 0.31 10.7 0.0 2.0 2 0 0 2 2 2 0 F-box-like domain F-box-like PF12937.2 KLO15752.1 - 8.4e-09 35.0 1.0 2.6e-07 30.2 0.2 3.0 3 0 0 3 3 3 1 F-box-like Sec8_exocyst PF04048.9 KLO15752.1 - 0.001 18.7 0.0 0.0019 17.8 0.0 1.4 1 0 0 1 1 1 1 Sec8 exocyst complex component specific domain F-box-like_2 PF13013.1 KLO15752.1 - 0.022 14.4 0.3 0.12 12.1 0.0 2.2 2 1 0 2 2 2 0 F-box-like domain F-box-like PF12937.2 KLO15753.1 - 0.00026 20.6 1.7 0.0028 17.3 0.1 2.8 3 0 0 3 3 3 1 F-box-like DUF4258 PF14076.1 KLO15753.1 - 0.084 12.8 0.4 0.58 10.2 0.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4258) Hydrophobin PF01185.13 KLO15754.1 - 1.3e-14 54.4 4.2 1.6e-14 54.1 2.9 1.1 1 0 0 1 1 1 1 Fungal hydrophobin MTP18 PF10558.4 KLO15755.1 - 1.1e-56 190.8 0.7 1.4e-56 190.5 0.5 1.1 1 0 0 1 1 1 1 Mitochondrial 18 KDa protein (MTP18) IF-2B PF01008.12 KLO15756.1 - 3.7e-78 262.3 0.0 4.4e-78 262.1 0.0 1.0 1 0 0 1 1 1 1 Initiation factor 2 subunit family PEP-utilizers PF00391.18 KLO15756.1 - 0.13 11.8 1.9 0.68 9.5 0.1 2.8 3 0 0 3 3 3 0 PEP-utilising enzyme, mobile domain XRN_N PF03159.13 KLO15757.1 - 1.5e-25 89.9 0.2 1.8e-25 89.7 0.1 1.0 1 0 0 1 1 1 1 XRN 5'-3' exonuclease N-terminus DUF606 PF04657.8 KLO15758.1 - 0.059 13.4 0.1 0.069 13.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function, DUF606 DUF4646 PF15496.1 KLO15759.1 - 7.4e-15 55.0 0.0 1.3e-14 54.2 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4646) Longin PF13774.1 KLO15760.1 - 3e-28 97.2 0.1 5e-28 96.4 0.1 1.4 1 0 0 1 1 1 1 Regulated-SNARE-like domain Synaptobrevin PF00957.16 KLO15760.1 - 1.6e-14 53.2 0.1 2.7e-14 52.5 0.0 1.4 1 0 0 1 1 1 1 Synaptobrevin DUF1664 PF07889.7 KLO15760.1 - 0.015 15.1 1.6 0.016 15.0 0.4 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) DUF962 PF06127.6 KLO15761.1 - 8.5e-24 83.2 5.3 3e-23 81.5 3.7 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF962) Hydrophobin PF01185.13 KLO15763.1 - 2.4e-12 47.1 7.0 2.9e-12 46.8 4.9 1.1 1 0 0 1 1 1 1 Fungal hydrophobin Sporozoite_P67 PF05642.6 KLO15763.1 - 0.042 11.7 3.0 0.045 11.6 2.1 1.0 1 0 0 1 1 1 0 Sporozoite P67 surface antigen DUF336 PF03928.9 KLO15763.1 - 0.096 12.4 0.1 0.11 12.2 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF336) Diacid_rec PF05651.8 KLO15763.1 - 0.14 11.6 0.1 0.14 11.5 0.1 1.3 1 0 0 1 1 1 0 Putative sugar diacid recognition TrbC PF04956.8 KLO15763.1 - 0.17 11.9 1.0 0.22 11.5 0.7 1.3 1 0 0 1 1 1 0 TrbC/VIRB2 family Hydrophobin PF01185.13 KLO15764.1 - 3.2e-13 49.9 5.5 4.1e-13 49.5 3.8 1.1 1 0 0 1 1 1 1 Fungal hydrophobin DUF336 PF03928.9 KLO15764.1 - 0.13 12.1 0.1 0.15 11.8 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF336) F-box-like PF12937.2 KLO15765.1 - 1.8e-06 27.5 8.4 1.4e-05 24.6 5.4 2.7 2 1 0 2 2 2 1 F-box-like F-box PF00646.28 KLO15765.1 - 0.0061 16.1 7.5 0.0061 16.1 5.2 3.3 4 1 0 4 4 4 1 F-box domain Peptidase_S10 PF00450.17 KLO15766.1 - 6.6e-99 331.8 0.0 8.3e-99 331.5 0.0 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Abhydrolase_5 PF12695.2 KLO15766.1 - 0.012 15.3 0.0 0.044 13.5 0.0 2.0 1 1 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KLO15766.1 - 0.014 15.2 0.0 0.26 11.1 0.0 2.3 2 1 0 2 2 2 0 Alpha/beta hydrolase family F-box-like PF12937.2 KLO15767.1 - 1.2e-06 28.1 5.8 1.5e-06 27.8 1.9 2.8 2 1 0 2 2 2 1 F-box-like F-box PF00646.28 KLO15767.1 - 0.047 13.3 5.9 0.52 10.0 2.5 3.4 2 1 0 2 2 2 0 F-box domain F-box-like PF12937.2 KLO15768.1 - 8.5e-07 28.5 1.7 5.6e-06 25.9 1.2 2.4 1 1 0 1 1 1 1 F-box-like F-box PF00646.28 KLO15768.1 - 0.22 11.1 4.4 1.1 8.9 1.2 3.1 2 1 0 2 2 2 0 F-box domain DUF3188 PF11384.3 KLO15768.1 - 5.7 6.5 5.4 0.66 9.5 0.5 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3188) F-box-like PF12937.2 KLO15769.1 - 4.9e-08 32.5 9.4 9.4e-08 31.6 4.8 2.6 2 1 0 2 2 2 1 F-box-like F-box PF00646.28 KLO15769.1 - 0.0011 18.5 7.1 0.13 11.9 0.5 3.1 3 0 0 3 3 3 2 F-box domain F-box-like PF12937.2 KLO15770.1 - 5.7e-05 22.7 5.0 5.7e-05 22.7 3.5 3.0 3 1 0 3 3 3 1 F-box-like F-box PF00646.28 KLO15770.1 - 0.057 13.1 8.9 0.31 10.7 1.0 3.5 3 0 0 3 3 3 0 F-box domain Peptidase_S10 PF00450.17 KLO15771.1 - 3.7e-72 243.7 0.0 3.8e-71 240.4 0.0 1.9 1 1 0 1 1 1 1 Serine carboxypeptidase F-box-like PF12937.2 KLO15772.1 - 1.6e-07 30.9 11.2 1.6e-07 30.9 4.2 3.0 2 1 0 2 2 2 1 F-box-like F-box PF00646.28 KLO15772.1 - 0.23 11.1 9.9 0.052 13.2 2.1 2.9 2 1 0 2 2 2 0 F-box domain DASH_Dam1 PF08653.5 KLO15773.1 - 0.11 12.2 0.2 0.25 11.1 0.2 1.6 1 0 0 1 1 1 0 DASH complex subunit Dam1 F-box-like PF12937.2 KLO15774.1 - 4.9e-09 35.7 4.8 2e-08 33.7 3.3 2.1 1 1 0 1 1 1 1 F-box-like F-box PF00646.28 KLO15774.1 - 0.00034 20.1 3.8 0.0016 18.0 2.6 2.2 1 1 0 1 1 1 1 F-box domain F-box-like PF12937.2 KLO15775.1 - 8.7e-10 38.1 0.2 2.2e-09 36.8 0.1 1.8 1 0 0 1 1 1 1 F-box-like Ferritin_2 PF13668.1 KLO15776.1 - 9.1e-34 116.3 0.3 1.4e-33 115.7 0.2 1.3 1 0 0 1 1 1 1 Ferritin-like domain EAF PF09816.4 KLO15777.1 - 1.1e-21 76.8 0.0 1.8e-21 76.1 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase II transcription elongation factor PGK PF00162.14 KLO15778.1 - 3.9e-146 486.5 0.0 4.4e-146 486.3 0.0 1.0 1 0 0 1 1 1 1 Phosphoglycerate kinase F-box-like PF12937.2 KLO15779.1 - 1.6e-09 37.3 0.4 3.4e-09 36.2 0.3 1.6 1 0 0 1 1 1 1 F-box-like F-box-like PF12937.2 KLO15780.1 - 9.1e-09 34.9 5.7 9.1e-09 34.9 3.9 2.5 2 1 0 2 2 2 1 F-box-like F-box PF00646.28 KLO15780.1 - 0.027 14.1 1.5 0.12 12.1 1.1 2.1 1 0 0 1 1 1 0 F-box domain F-box-like PF12937.2 KLO15781.1 - 0.0019 17.8 0.1 0.02 14.6 0.1 2.8 1 1 0 1 1 1 1 F-box-like Peptidase_S10 PF00450.17 KLO15782.1 - 3.7e-95 319.5 0.0 4.6e-95 319.2 0.0 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase F-box-like PF12937.2 KLO15783.1 - 1.2e-10 40.9 5.7 5.6e-10 38.7 4.0 2.1 1 1 0 1 1 1 1 F-box-like F-box PF00646.28 KLO15783.1 - 9.4e-05 21.9 3.7 0.0017 17.9 2.5 2.9 1 1 0 1 1 1 1 F-box domain F-box-like PF12937.2 KLO15784.1 - 2.5e-08 33.5 5.2 1.1e-07 31.4 1.2 2.6 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 KLO15784.1 - 0.00086 18.8 1.1 0.014 15.0 0.3 3.0 2 1 0 2 2 2 1 F-box domain F-box-like_2 PF13013.1 KLO15784.1 - 0.0027 17.4 0.7 0.0065 16.1 0.5 1.6 1 0 0 1 1 1 1 F-box-like domain PUF PF00806.14 KLO15785.1 - 9.9e-16 56.2 0.0 0.0019 17.5 0.0 7.5 9 0 0 9 9 9 5 Pumilio-family RNA binding repeat Astacin PF01400.19 KLO15786.1 - 6.4e-08 32.2 0.6 2.8e-07 30.1 0.4 2.2 1 1 0 1 1 1 1 Astacin (Peptidase family M12A) Peptidase_M10 PF00413.19 KLO15786.1 - 1.4e-05 24.8 2.1 0.022 14.5 0.5 2.4 2 0 0 2 2 2 2 Matrixin Reprolysin_5 PF13688.1 KLO15786.1 - 0.0011 18.8 0.5 0.0021 18.0 0.1 1.7 1 1 0 1 1 1 1 Metallo-peptidase family M12 Peptidase_M43 PF05572.8 KLO15786.1 - 0.007 15.9 0.1 0.013 15.0 0.1 1.5 1 0 0 1 1 1 1 Pregnancy-associated plasma protein-A Reprolysin_3 PF13582.1 KLO15786.1 - 0.0099 16.4 0.3 0.05 14.1 0.0 2.2 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like DUF1466 PF07326.6 KLO15786.1 - 0.011 15.0 0.6 0.088 12.1 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1466) Reprolysin_2 PF13574.1 KLO15786.1 - 0.012 15.7 0.1 0.016 15.2 0.0 1.4 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Peptidase_M66 PF10462.4 KLO15786.1 - 0.02 13.7 3.1 0.02 13.7 1.5 1.4 1 1 0 1 1 1 0 Peptidase M66 Reprolysin_4 PF13583.1 KLO15786.1 - 0.031 13.7 0.1 0.048 13.1 0.1 1.4 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Osteopontin PF00865.13 KLO15786.1 - 1.8 7.7 11.1 3 7.0 7.7 1.3 1 0 0 1 1 1 0 Osteopontin DUF1793 PF08760.6 KLO15787.1 - 6.1e-25 88.0 0.0 1e-24 87.3 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1793) Bac_rhamnosid PF05592.6 KLO15787.1 - 0.004 15.4 0.0 0.0061 14.8 0.0 1.2 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase DUF1793 PF08760.6 KLO15788.1 - 7.9e-23 81.1 0.0 1.3e-22 80.4 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1793) Bac_rhamnosid PF05592.6 KLO15788.1 - 0.0051 15.0 0.0 0.0094 14.2 0.0 1.4 1 1 0 1 1 1 1 Bacterial alpha-L-rhamnosidase GBA2_N PF12215.3 KLO15788.1 - 0.11 11.6 0.2 0.24 10.5 0.1 1.5 1 0 0 1 1 1 0 beta-Glucocerebrosidase 2 N terminal DUF1793 PF08760.6 KLO15790.1 - 8.9e-27 94.0 0.0 1.4e-26 93.3 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1793) Bac_rhamnosid PF05592.6 KLO15790.1 - 0.00013 20.3 0.0 0.00013 20.3 0.0 1.4 2 0 0 2 2 2 1 Bacterial alpha-L-rhamnosidase DUF1191 PF06697.7 KLO15790.1 - 0.14 10.9 0.1 0.26 10.0 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1191) DUF2273 PF10031.4 KLO15790.1 - 1 9.0 4.9 2.7 7.6 3.4 1.7 1 0 0 1 1 1 0 Small integral membrane protein (DUF2273) 2OG-FeII_Oxy_3 PF13640.1 KLO15791.1 - 1.8e-06 28.3 0.0 7.9e-06 26.3 0.0 1.9 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.15 KLO15791.1 - 3.6e-06 27.1 0.0 1.1e-05 25.6 0.0 1.7 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily F-box-like PF12937.2 KLO15792.1 - 5.9e-05 22.6 3.5 0.00013 21.6 2.4 1.6 1 0 0 1 1 1 1 F-box-like DUF1793 PF08760.6 KLO15793.1 - 1.9e-27 96.2 0.0 2.9e-27 95.5 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1793) Bac_rhamnosid PF05592.6 KLO15793.1 - 0.00093 17.5 0.2 0.0077 14.4 0.0 2.0 2 0 0 2 2 2 1 Bacterial alpha-L-rhamnosidase Nitrate_red_gam PF02665.9 KLO15793.1 - 0.0046 16.3 0.0 0.01 15.2 0.0 1.5 1 0 0 1 1 1 1 Nitrate reductase gamma subunit Orthopox_B11R PF07033.6 KLO15794.1 - 0.091 12.2 0.0 0.13 11.7 0.0 1.2 1 0 0 1 1 1 0 Orthopoxvirus B11R protein GBA2_N PF12215.3 KLO15795.1 - 0.00081 18.6 0.2 0.0017 17.5 0.1 1.5 1 0 0 1 1 1 1 beta-Glucocerebrosidase 2 N terminal Glyco_hydro_52 PF03512.8 KLO15795.1 - 0.041 12.4 0.0 0.064 11.8 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 52 DUF1793 PF08760.6 KLO15796.1 - 4.9e-15 55.8 0.2 9.4e-15 54.8 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1793) Bac_rhamnosid PF05592.6 KLO15796.1 - 0.037 12.2 0.0 0.056 11.6 0.0 1.2 1 0 0 1 1 1 0 Bacterial alpha-L-rhamnosidase GBA2_N PF12215.3 KLO15796.1 - 0.068 12.3 0.1 0.12 11.4 0.1 1.4 1 0 0 1 1 1 0 beta-Glucocerebrosidase 2 N terminal Golgin_A5 PF09787.4 KLO15797.1 - 0.012 14.1 2.5 0.016 13.7 1.7 1.1 1 0 0 1 1 1 0 Golgin subfamily A member 5 DUF1793 PF08760.6 KLO15798.1 - 3.4e-15 56.3 0.0 6.7e-15 55.3 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1793) Bac_rhamnosid PF05592.6 KLO15798.1 - 0.011 13.9 0.0 0.02 13.1 0.0 1.4 1 0 0 1 1 1 0 Bacterial alpha-L-rhamnosidase Glyco_hydro_52 PF03512.8 KLO15798.1 - 0.011 14.3 0.0 0.018 13.6 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 52 GBA2_N PF12215.3 KLO15798.1 - 0.039 13.1 0.1 0.065 12.3 0.1 1.3 1 0 0 1 1 1 0 beta-Glucocerebrosidase 2 N terminal Pinin_SDK_N PF04697.8 KLO15799.1 - 0.068 13.2 0.2 0.23 11.4 0.1 1.7 1 1 1 2 2 2 0 pinin/SDK conserved region DUF1793 PF08760.6 KLO15800.1 - 1.6e-24 86.6 0.0 2.9e-24 85.8 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1793) GBA2_N PF12215.3 KLO15800.1 - 0.033 13.3 0.2 0.063 12.4 0.1 1.4 1 0 0 1 1 1 0 beta-Glucocerebrosidase 2 N terminal DUF1793 PF08760.6 KLO15801.1 - 3.6e-24 85.5 0.0 6.3e-24 84.7 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1793) Bac_rhamnosid PF05592.6 KLO15801.1 - 0.1 10.8 0.2 0.66 8.1 0.0 2.0 2 0 0 2 2 2 0 Bacterial alpha-L-rhamnosidase PalH PF08733.5 KLO15802.1 - 0.37 9.5 6.0 2.4 6.8 4.2 2.0 1 1 0 1 1 1 0 PalH/RIM21 Baculo_gp64 PF03273.8 KLO15806.1 - 0.12 10.5 0.0 0.12 10.5 0.0 1.1 1 0 0 1 1 1 0 Baculovirus gp64 envelope glycoprotein family SNF2_N PF00176.18 KLO15808.1 - 4.5e-77 258.7 0.1 9.4e-77 257.7 0.0 1.6 2 0 0 2 2 2 1 SNF2 family N-terminal domain SLIDE PF09111.5 KLO15808.1 - 1.1e-41 141.2 1.7 1.1e-41 141.2 1.2 2.3 2 0 0 2 2 2 1 SLIDE HAND PF09110.6 KLO15808.1 - 3.3e-29 101.5 5.0 1.7e-28 99.2 3.5 2.4 1 0 0 1 1 1 1 HAND Helicase_C PF00271.26 KLO15808.1 - 4.7e-15 55.2 0.0 1.4e-14 53.7 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 KLO15808.1 - 4.9e-09 36.2 0.0 2.4e-08 34.0 0.0 2.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.24 KLO15808.1 - 2.9e-08 33.3 0.0 7.1e-08 32.1 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase HDA2-3 PF11496.3 KLO15808.1 - 5.1e-06 25.5 0.0 1.1e-05 24.4 0.0 1.5 1 0 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 AAA_14 PF13173.1 KLO15808.1 - 0.0046 16.8 0.1 0.024 14.5 0.0 2.3 2 0 0 2 2 2 1 AAA domain DBINO PF13892.1 KLO15808.1 - 0.0095 15.9 0.2 0.0095 15.9 0.1 3.5 4 0 0 4 4 3 1 DNA-binding domain DEAD_2 PF06733.10 KLO15808.1 - 0.019 14.4 0.5 0.045 13.1 0.3 1.6 1 0 0 1 1 1 0 DEAD_2 Myb_DNA-bind_6 PF13921.1 KLO15808.1 - 0.18 11.8 4.1 1.5 9.0 0.1 3.4 3 0 0 3 3 3 0 Myb-like DNA-binding domain EI24 PF07264.6 KLO15809.1 - 0.00061 19.2 3.6 0.0016 17.9 2.5 1.7 1 1 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) AhpC-TSA_2 PF13911.1 KLO15810.1 - 5.7e-18 64.9 0.0 1.1e-17 64.0 0.0 1.5 2 0 0 2 2 2 1 AhpC/TSA antioxidant enzyme AhpC-TSA PF00578.16 KLO15810.1 - 6.7e-11 41.9 0.0 8.4e-11 41.6 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 KLO15810.1 - 2.3e-10 40.2 0.0 3.1e-10 39.7 0.0 1.1 1 0 0 1 1 1 1 Redoxin Thioredoxin_8 PF13905.1 KLO15810.1 - 0.026 14.6 0.0 0.039 14.0 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin-like Thioredoxin PF00085.15 KLO15810.1 - 0.044 13.4 0.0 0.071 12.7 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin Aft1_HRA PF11786.3 KLO15811.1 - 0.86 9.9 7.6 3.8 7.8 2.4 3.0 1 1 1 2 2 2 0 Aft1 HRA domain SMC_N PF02463.14 KLO15813.1 - 1.9e-74 249.6 8.1 3.6e-74 248.7 5.6 1.5 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 KLO15813.1 - 2.9e-28 98.2 0.0 8.8e-28 96.6 0.0 1.9 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.1 KLO15813.1 - 5.5e-14 52.8 8.0 6.9e-07 29.5 0.2 3.1 2 1 0 2 2 2 2 AAA domain AAA_29 PF13555.1 KLO15813.1 - 1.4e-06 27.7 0.0 2.7e-06 26.7 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_13 PF13166.1 KLO15813.1 - 0.0017 16.9 17.8 0.0017 16.9 12.3 7.0 5 2 2 7 7 7 2 AAA domain Reo_sigmaC PF04582.7 KLO15813.1 - 0.015 14.5 24.9 0.012 14.8 1.1 4.1 2 2 2 4 4 4 0 Reovirus sigma C capsid protein Fib_alpha PF08702.5 KLO15813.1 - 0.2 11.7 69.3 0.068 13.2 6.2 6.9 3 3 1 5 5 5 0 Fibrinogen alpha/beta chain family ABC_tran PF00005.22 KLO15813.1 - 0.28 11.4 0.0 0.28 11.4 0.0 5.7 4 2 0 4 4 4 0 ABC transporter DUF1932 PF09130.6 KLO15814.1 - 3.8e-14 52.1 0.0 1.1e-13 50.6 0.0 1.9 1 1 0 1 1 1 1 Domain of unknown function (DUF1932) NAD_binding_2 PF03446.10 KLO15814.1 - 1.8e-09 37.6 0.0 2.9e-09 36.9 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.12 KLO15814.1 - 7.7e-08 32.6 0.0 1.8e-07 31.4 0.0 1.7 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Rossmann-like PF10727.4 KLO15814.1 - 0.00027 20.6 0.2 0.00057 19.6 0.1 1.5 1 0 0 1 1 1 1 Rossmann-like domain IlvN PF07991.7 KLO15814.1 - 0.00061 19.1 0.0 0.0011 18.3 0.0 1.3 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain NAD_binding_10 PF13460.1 KLO15814.1 - 0.0057 16.6 0.2 0.022 14.7 0.1 2.0 2 0 0 2 2 2 1 NADH(P)-binding 3HCDH_N PF02737.13 KLO15814.1 - 0.025 14.2 0.0 0.047 13.3 0.0 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain YjeF_N PF03853.10 KLO15814.1 - 0.066 12.8 0.0 0.31 10.6 0.0 1.9 2 0 0 2 2 2 0 YjeF-related protein N-terminus Pkinase_Tyr PF07714.12 KLO15815.1 - 2.7e-41 141.3 0.0 4e-41 140.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 KLO15815.1 - 1.8e-37 128.9 0.0 2.8e-37 128.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.18 KLO15815.1 - 0.0017 18.1 0.0 0.0041 16.8 0.0 1.7 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.1 KLO15815.1 - 0.019 13.9 0.0 0.033 13.1 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Kdo PF06293.9 KLO15815.1 - 0.13 11.3 0.1 0.25 10.4 0.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Abhydrolase_6 PF12697.2 KLO15816.1 - 4.6e-23 82.2 0.0 5.6e-23 82.0 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KLO15816.1 - 3.4e-10 39.8 0.0 5.3e-10 39.2 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KLO15816.1 - 1.8e-08 34.2 0.0 2.5e-08 33.7 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 KLO15816.1 - 3.9e-05 23.4 0.1 7.3e-05 22.5 0.1 1.4 1 0 0 1 1 1 1 Putative lysophospholipase RIX1 PF08167.7 KLO15817.1 - 0.027 14.1 0.3 0.11 12.1 0.0 2.1 2 0 0 2 2 2 0 rRNA processing/ribosome biogenesis Mto2_bdg PF12808.2 KLO15818.1 - 0.14 12.2 2.6 0.24 11.5 1.8 1.3 1 0 0 1 1 1 0 Micro-tubular organiser Mto1 C-term Mto2-binding region Erythro-docking PF09277.6 KLO15819.1 - 0.08 12.6 0.1 0.24 11.0 0.1 1.8 1 0 0 1 1 1 0 Erythronolide synthase, docking HA PF03457.9 KLO15820.1 - 0.03 14.4 0.1 0.07 13.2 0.0 1.6 1 0 0 1 1 1 0 Helicase associated domain SGS PF05002.10 KLO15820.1 - 0.077 12.7 1.0 3 7.6 0.0 2.9 2 1 1 3 3 3 0 SGS domain Beach PF02138.13 KLO15821.1 - 0.026 13.9 0.2 0.034 13.5 0.1 1.1 1 0 0 1 1 1 0 Beige/BEACH domain Calc_CGRP_IAPP PF00214.14 KLO15821.1 - 0.27 11.2 2.9 0.36 10.8 2.0 1.1 1 0 0 1 1 1 0 Calcitonin / CGRP / IAPP family VWC PF00093.13 KLO15821.1 - 1.2 9.2 5.1 3.1 7.9 3.5 1.8 1 1 0 1 1 1 0 von Willebrand factor type C domain DUF3128 PF11326.3 KLO15822.1 - 4.9e-18 65.0 0.1 6.3e-18 64.6 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3128) MFS_1 PF07690.11 KLO15824.1 - 6.4e-21 74.4 31.9 1.3e-16 60.2 11.6 2.7 2 1 1 3 3 3 3 Major Facilitator Superfamily Abhydrolase_6 PF12697.2 KLO15825.1 - 5.3e-25 88.6 0.0 6.5e-25 88.3 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KLO15825.1 - 1.4e-10 41.1 0.0 5.7e-10 39.1 0.0 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KLO15825.1 - 2.3e-08 33.9 0.0 3.3e-08 33.4 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 KLO15825.1 - 2.2e-06 27.4 0.5 4.8e-06 26.3 0.1 1.7 2 0 0 2 2 2 1 Putative lysophospholipase ADH_N PF08240.7 KLO15826.1 - 2.8e-23 81.7 0.1 5.9e-23 80.7 0.1 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KLO15826.1 - 5.5e-14 51.8 0.6 2.8e-13 49.5 0.4 2.0 1 1 0 1 1 1 1 Zinc-binding dehydrogenase TrkA_N PF02254.13 KLO15826.1 - 0.0012 18.8 0.0 0.0026 17.7 0.0 1.6 1 0 0 1 1 1 1 TrkA-N domain 2-Hacid_dh_C PF02826.14 KLO15826.1 - 0.0075 15.4 0.0 0.012 14.7 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.16 KLO15826.1 - 0.086 12.3 0.1 0.15 11.6 0.1 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Methyltransf_18 PF12847.2 KLO15826.1 - 0.11 13.0 0.0 0.29 11.7 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase domain FAD_binding_3 PF01494.14 KLO15826.1 - 0.13 11.3 0.1 0.18 10.8 0.1 1.2 1 0 0 1 1 1 0 FAD binding domain DUF1793 PF08760.6 KLO15829.1 - 2.5e-31 108.8 0.0 4.6e-31 107.9 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1793) GBA2_N PF12215.3 KLO15829.1 - 0.0048 16.0 0.0 0.0092 15.1 0.0 1.3 1 0 0 1 1 1 1 beta-Glucocerebrosidase 2 N terminal Syndecan PF01034.15 KLO15829.1 - 0.057 13.0 0.0 0.13 11.8 0.0 1.6 1 0 0 1 1 1 0 Syndecan domain Tox-WTIP PF15654.1 KLO15831.1 - 0.11 12.0 1.4 0.85 9.2 0.5 2.3 2 0 0 2 2 2 0 Toxin with a conserved tryptophan and TIP tripeptide motif RIO1 PF01163.17 KLO15833.1 - 0.069 12.4 0.0 0.079 12.3 0.0 1.2 1 0 0 1 1 1 0 RIO1 family Tox-WTIP PF15654.1 KLO15837.1 - 0.15 11.6 2.7 0.16 11.6 0.6 2.0 2 0 0 2 2 2 0 Toxin with a conserved tryptophan and TIP tripeptide motif DUF2781 PF10914.3 KLO15837.1 - 0.65 9.7 7.7 1.4 8.6 0.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2781) Spt5-NGN PF03439.8 KLO15840.1 - 1.2e-12 47.3 0.0 2.1e-12 46.6 0.0 1.4 1 0 0 1 1 1 1 Early transcription elongation factor of RNA pol II, NGN section KOW PF00467.24 KLO15840.1 - 4.8e-07 29.2 30.4 0.024 14.3 0.9 6.1 6 0 0 6 6 6 4 KOW motif Spt5_N PF11942.3 KLO15840.1 - 0.004 17.7 8.3 0.0096 16.5 5.8 1.6 1 0 0 1 1 1 1 Spt5 transcription elongation factor, acidic N-terminal HAS-barrel PF09378.5 KLO15840.1 - 0.16 11.9 2.3 13 5.7 0.0 3.4 3 0 0 3 3 3 0 HAS barrel domain PolyA_pol_arg_C PF12626.2 KLO15846.1 - 0.094 12.3 0.2 0.26 10.9 0.0 1.7 2 0 0 2 2 2 0 Polymerase A arginine-rich C-terminus Tox-WTIP PF15654.1 KLO15848.1 - 0.13 11.8 0.6 1.8 8.2 0.2 2.3 2 0 0 2 2 2 0 Toxin with a conserved tryptophan and TIP tripeptide motif DUF4170 PF13773.1 KLO15852.1 - 0.027 14.3 0.0 0.075 12.9 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4170) p450 PF00067.17 KLO15853.1 - 3.9e-61 206.9 0.0 4.9e-61 206.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 F-box-like PF12937.2 KLO15854.1 - 5.8e-05 22.7 0.2 5.8e-05 22.7 0.1 2.7 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 KLO15854.1 - 0.27 10.9 3.1 1.9 8.2 1.1 3.2 2 1 0 2 2 2 0 F-box domain F-box-like PF12937.2 KLO15855.1 - 7.6e-06 25.5 0.9 7.6e-06 25.5 0.6 2.6 3 0 0 3 3 3 1 F-box-like F-box PF00646.28 KLO15855.1 - 0.00039 20.0 0.2 0.0016 18.0 0.1 2.2 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 KLO15856.1 - 1.3e-07 31.2 0.9 3.7e-07 29.7 0.6 1.8 1 0 0 1 1 1 1 F-box-like FH2 PF02181.18 KLO15857.1 - 0.063 12.1 1.5 0.16 10.8 0.0 2.0 2 0 0 2 2 2 0 Formin Homology 2 Domain DUF2370 PF10176.4 KLO15858.1 - 2.1e-67 226.8 0.0 3.9e-67 226.0 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2370) Ank_2 PF12796.2 KLO15859.1 - 7.1e-22 77.5 0.0 2.8e-13 50.0 0.0 2.5 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 KLO15859.1 - 6.6e-21 73.0 0.5 1.6e-08 33.9 0.0 4.9 5 0 0 5 5 5 3 Ankyrin repeat Ank_5 PF13857.1 KLO15859.1 - 9.9e-18 63.7 1.0 1.2e-07 31.7 0.2 3.6 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_4 PF13637.1 KLO15859.1 - 1.1e-17 64.0 2.3 1.6e-11 44.3 0.1 4.3 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 KLO15859.1 - 9.6e-13 47.0 1.7 1.2e-05 25.1 0.1 4.5 5 0 0 5 5 5 3 Ankyrin repeat CUB_2 PF02408.15 KLO15859.1 - 0.33 10.5 2.6 1.7 8.1 0.0 2.4 2 0 0 2 2 2 0 CUB-like domain B3_4 PF03483.12 KLO15860.1 - 9.7e-28 96.7 0.1 1.7e-27 95.9 0.1 1.4 1 0 0 1 1 1 1 B3/4 domain B5 PF03484.10 KLO15860.1 - 2.5e-18 65.6 0.0 1.4e-15 56.8 0.0 2.6 2 0 0 2 2 2 2 tRNA synthetase B5 domain DUF469 PF04320.9 KLO15860.1 - 0.042 14.6 0.5 0.13 13.0 0.2 2.0 2 0 0 2 2 2 0 Protein with unknown function (DUF469) MFS_2 PF13347.1 KLO15861.1 - 1.3e-09 36.9 4.5 1.3e-09 36.9 3.2 2.4 2 0 0 2 2 2 2 MFS/sugar transport protein MFS_1 PF07690.11 KLO15861.1 - 5.3e-08 31.9 29.7 7e-06 24.9 15.3 3.0 2 1 1 3 3 3 2 Major Facilitator Superfamily MFS_1_like PF12832.2 KLO15861.1 - 0.44 10.3 0.0 0.44 10.3 0.0 3.4 3 0 0 3 3 3 0 MFS_1 like family ATP_bind_4 PF01902.12 KLO15862.1 - 1e-41 142.7 0.0 1.1e-32 113.1 0.0 2.1 2 0 0 2 2 2 2 ATP-binding region Ribonuc_L-PSP PF01042.16 KLO15862.1 - 3e-22 78.6 0.0 7.1e-12 45.1 0.0 2.5 2 1 0 2 2 2 2 Endoribonuclease L-PSP tRNA_Me_trans PF03054.11 KLO15862.1 - 0.1 11.1 0.0 0.17 10.3 0.0 1.3 1 0 0 1 1 1 0 tRNA methyl transferase Cactin_mid PF10312.4 KLO15863.1 - 1.2e-59 200.7 4.9 1.2e-59 200.7 3.4 2.3 3 0 0 3 3 3 1 Conserved mid region of cactin CactinC_cactus PF09732.4 KLO15863.1 - 3.7e-57 191.3 7.3 7.3e-57 190.3 5.0 1.5 1 0 0 1 1 1 1 Cactus-binding C-terminus of cactin protein Amino_oxidase PF01593.19 KLO15863.1 - 0.61 9.0 7.5 2.3 7.2 5.2 1.9 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase JAB PF01398.16 KLO15864.1 - 5.7e-34 116.2 0.1 9.8e-34 115.5 0.1 1.4 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.1 KLO15864.1 - 1.1e-26 93.1 2.9 2.1e-26 92.2 2.0 1.4 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function Prok-JAB PF14464.1 KLO15864.1 - 2.2e-08 33.6 0.0 3.7e-08 32.8 0.0 1.4 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain YIF1 PF03878.10 KLO15865.1 - 2.4e-74 249.4 0.3 3.1e-74 249.1 0.2 1.1 1 0 0 1 1 1 1 YIF1 Yip1 PF04893.12 KLO15865.1 - 0.0008 18.9 3.1 0.002 17.6 2.1 1.6 1 0 0 1 1 1 1 Yip1 domain Syntaxin-18_N PF10496.4 KLO15866.1 - 2.7e-14 52.7 0.7 2.7e-14 52.7 0.5 2.5 2 0 0 2 2 2 1 SNARE-complex protein Syntaxin-18 N-terminus SNARE PF05739.14 KLO15866.1 - 0.0013 18.3 3.0 0.0051 16.4 2.1 2.2 1 0 0 1 1 1 1 SNARE domain Snapin_Pallidin PF14712.1 KLO15866.1 - 1.4 9.3 9.4 0.5 10.7 1.3 3.1 3 0 0 3 3 3 0 Snapin/Pallidin DUF1179 PF06678.6 KLO15866.1 - 3.2 8.1 0.0 3.2 8.1 0.0 3.1 3 1 0 3 3 3 0 Protein of unknown function (DUF1179) SNARE_assoc PF09335.6 KLO15867.1 - 9.7e-13 48.4 11.5 1.8e-11 44.2 5.9 2.8 2 1 1 3 3 3 1 SNARE associated Golgi protein DUF4366 PF14283.1 KLO15867.1 - 0.14 11.5 0.0 0.25 10.7 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) Afaf PF15339.1 KLO15867.1 - 0.22 11.0 0.3 2.1 7.8 0.0 2.0 2 0 0 2 2 2 0 Acrosome formation-associated factor HAMP PF00672.20 KLO15867.1 - 1.2 9.4 0.0 1.2 9.4 0.0 3.2 3 0 0 3 3 3 0 HAMP domain MHYT PF03707.11 KLO15867.1 - 3.9 7.6 8.1 3.2 7.9 0.3 3.3 3 0 0 3 3 3 0 Bacterial signalling protein N terminal repeat DUF3402 PF11882.3 KLO15868.1 - 1.1e-118 396.8 0.2 4.9e-118 394.7 0.1 1.8 1 1 0 1 1 1 1 Domain of unknown function (DUF3402) N1221 PF07923.8 KLO15868.1 - 1e-48 165.6 0.1 1.6e-48 165.0 0.1 1.3 1 0 0 1 1 1 1 N1221-like protein Cyclin PF08613.6 KLO15869.1 - 7.4e-05 23.1 0.0 0.00014 22.2 0.0 1.4 1 0 0 1 1 1 1 Cyclin ThiF PF00899.16 KLO15870.1 - 6.6e-47 158.7 0.0 3.8e-28 98.0 0.0 2.5 2 0 0 2 2 2 2 ThiF family UBA_e1_C PF09358.5 KLO15870.1 - 6.3e-45 152.3 1.7 7.7e-45 152.1 0.5 1.6 2 0 0 2 2 2 1 Ubiquitin-activating enzyme e1 C-terminal domain UBACT PF02134.16 KLO15870.1 - 1.2e-38 130.4 4.0 1.1e-26 92.1 0.2 4.0 4 0 0 4 4 4 2 Repeat in ubiquitin-activating (UBA) protein UBA_e1_thiolCys PF10585.4 KLO15870.1 - 1.8e-23 81.6 3.9 1.1e-19 69.5 0.3 2.5 2 0 0 2 2 2 2 Ubiquitin-activating enzyme active site Shikimate_DH PF01488.15 KLO15870.1 - 0.13 12.3 0.0 0.42 10.7 0.0 1.9 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase zf-CSL PF05207.8 KLO15871.1 - 0.13 11.8 1.0 0.62 9.6 0.7 2.0 1 1 0 1 1 1 0 CSL zinc finger Mt_ATP-synt_D PF05873.7 KLO15872.1 - 0.0064 16.1 0.6 0.014 15.0 0.2 1.7 1 1 0 1 1 1 1 ATP synthase D chain, mitochondrial (ATP5H) Jnk-SapK_ap_N PF09744.4 KLO15872.1 - 0.016 15.1 2.4 0.016 15.1 1.7 3.1 2 1 1 3 3 3 0 JNK_SAPK-associated protein-1 DUF948 PF06103.6 KLO15872.1 - 0.15 11.9 10.9 0.33 10.8 3.5 3.2 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) LLC1 PF14945.1 KLO15872.1 - 1.1 9.5 5.1 8.9 6.6 0.3 2.6 2 0 0 2 2 2 0 Normal lung function maintenance, Low in Lung Cancer 1 protein DivIC PF04977.10 KLO15872.1 - 3.8 7.0 21.9 0.67 9.4 1.2 4.4 3 1 1 4 4 4 0 Septum formation initiator Sec20 PF03908.8 KLO15872.1 - 5.3 6.8 9.9 0.8 9.4 1.2 2.9 1 1 1 2 2 2 0 Sec20 SlyX PF04102.7 KLO15872.1 - 5.9 7.3 24.4 2.2 8.7 0.9 4.1 3 1 0 4 4 4 0 SlyX DUF1664 PF07889.7 KLO15872.1 - 9.7 6.0 15.5 11 5.7 4.6 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) DNA_pol_E_B PF04042.11 KLO15873.1 - 4.4e-34 117.5 0.1 9e-34 116.5 0.1 1.5 1 1 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B Fungal_trans PF04082.13 KLO15874.1 - 1.2e-22 80.0 0.7 2.3e-22 79.1 0.5 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KLO15874.1 - 3.2e-07 30.1 8.2 7.6e-07 28.9 5.7 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Diphthamide_syn PF01866.12 KLO15875.1 - 3.3e-91 305.7 0.0 3.1e-56 190.8 0.0 2.2 2 0 0 2 2 2 2 Putative diphthamide synthesis protein RRM_1 PF00076.17 KLO15876.1 - 3.9e-12 45.6 0.0 6e-12 45.0 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KLO15876.1 - 8.2e-07 28.9 0.0 1.4e-06 28.1 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KLO15876.1 - 5.4e-05 22.9 0.0 7.9e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Patched PF02460.13 KLO15877.1 - 1.9e-71 241.1 2.4 5e-67 226.4 1.8 2.9 2 1 0 2 2 2 2 Patched family Sterol-sensing PF12349.3 KLO15877.1 - 3e-46 156.6 16.5 1.2e-24 86.4 0.4 3.6 3 0 0 3 3 3 3 Sterol-sensing domain of SREBP cleavage-activation ACR_tran PF00873.14 KLO15877.1 - 1.1e-05 23.1 1.9 1.8e-05 22.4 1.3 1.2 1 0 0 1 1 1 1 AcrB/AcrD/AcrF family Folate_rec PF03024.9 KLO15877.1 - 4.9e-05 23.0 1.4 9.9e-05 22.0 1.0 1.5 1 0 0 1 1 1 1 Folate receptor family DUF4200 PF13863.1 KLO15878.1 - 0.074 12.9 3.1 0.12 12.2 2.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) zf-H2C2_2 PF13465.1 KLO15879.1 - 5.8e-10 38.9 8.0 1.9e-06 27.8 0.1 3.4 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2_4 PF13894.1 KLO15879.1 - 4.2e-08 32.9 8.5 0.0012 19.0 0.6 2.3 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.21 KLO15879.1 - 3.6e-07 30.1 10.7 0.00021 21.4 1.7 2.4 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-met PF12874.2 KLO15879.1 - 0.004 17.2 3.3 1.5 9.1 0.2 2.5 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 KLO15879.1 - 8.3 6.6 8.4 1.1 9.4 0.2 2.6 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding NAD_binding_1 PF00175.16 KLO15880.1 - 5.8e-17 62.2 0.0 1.4e-16 60.9 0.0 1.6 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.19 KLO15880.1 - 3.9e-09 36.5 0.0 8.6e-09 35.4 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.7 KLO15880.1 - 2.9e-06 27.2 0.0 0.00024 21.0 0.0 2.3 1 1 1 2 2 2 2 Ferric reductase NAD binding domain tRNA-synt_2d PF01409.15 KLO15881.1 - 9.9e-89 296.7 0.0 1.4e-88 296.2 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II core domain (F) tRNA-synt_2b PF00587.20 KLO15881.1 - 9.7e-07 28.5 0.0 1.8e-06 27.6 0.0 1.6 1 1 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) tRNA-synt_2 PF00152.15 KLO15881.1 - 6.6e-05 21.8 0.2 0.00099 17.9 0.0 2.7 3 1 1 4 4 4 1 tRNA synthetases class II (D, K and N) HTH_45 PF14947.1 KLO15881.1 - 0.12 12.1 0.0 7.5 6.4 0.0 2.4 2 0 0 2 2 2 0 Winged helix-turn-helix HTH_27 PF13463.1 KLO15881.1 - 0.17 12.2 1.1 25 5.2 0.2 3.3 3 0 0 3 3 3 0 Winged helix DNA-binding domain ParA PF10609.4 KLO15882.1 - 1.6e-30 104.7 0.0 2.9e-30 103.9 0.0 1.4 1 0 0 1 1 1 1 ParA/MinD ATPase like CbiA PF01656.18 KLO15882.1 - 5.2e-13 48.8 0.4 1.6e-12 47.2 0.3 1.7 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.1 KLO15882.1 - 0.00042 20.2 0.1 0.002 18.0 0.0 1.9 2 0 0 2 2 2 1 AAA domain ArsA_ATPase PF02374.10 KLO15882.1 - 0.0051 15.8 2.7 0.14 11.1 1.1 2.3 3 0 0 3 3 3 1 Anion-transporting ATPase MipZ PF09140.6 KLO15882.1 - 0.0086 15.1 0.0 0.015 14.4 0.0 1.3 1 0 0 1 1 1 1 ATPase MipZ AAA_25 PF13481.1 KLO15882.1 - 0.042 13.2 0.1 0.38 10.1 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_2 PF07724.9 KLO15884.1 - 8.1e-37 126.7 0.0 1.4e-36 125.9 0.0 1.3 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA PF00004.24 KLO15884.1 - 1.6e-15 57.4 0.0 3.1e-15 56.5 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.4 KLO15884.1 - 3.3e-09 36.5 0.0 8.5e-09 35.1 0.0 1.7 2 0 0 2 2 1 1 C-terminal, D2-small domain, of ClpB protein Mg_chelatase PF01078.16 KLO15884.1 - 2.1e-05 23.7 0.1 0.0004 19.5 0.0 2.6 2 1 1 3 3 3 1 Magnesium chelatase, subunit ChlI AAA_22 PF13401.1 KLO15884.1 - 5.4e-05 23.3 0.1 0.0023 18.0 0.1 2.6 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 KLO15884.1 - 6.7e-05 22.7 0.0 0.00015 21.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.9 KLO15884.1 - 0.00011 21.9 0.0 0.00026 20.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_17 PF13207.1 KLO15884.1 - 0.00015 22.5 0.0 0.00041 21.1 0.0 1.8 1 0 0 1 1 1 1 AAA domain DEAD PF00270.24 KLO15884.1 - 0.0021 17.5 0.0 0.014 14.8 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_16 PF13191.1 KLO15884.1 - 0.0038 17.2 0.4 0.016 15.1 0.0 2.2 3 0 0 3 3 2 1 AAA ATPase domain T2SE PF00437.15 KLO15884.1 - 0.0038 16.1 0.0 0.0061 15.4 0.0 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_24 PF13479.1 KLO15884.1 - 0.0039 16.8 0.0 0.0096 15.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.12 KLO15884.1 - 0.0041 16.5 0.0 0.0079 15.6 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein ABC_tran PF00005.22 KLO15884.1 - 0.0051 17.0 0.0 0.011 16.0 0.0 1.5 1 0 0 1 1 1 1 ABC transporter RuvB_N PF05496.7 KLO15884.1 - 0.012 14.6 0.0 0.14 11.2 0.0 2.1 2 0 0 2 2 2 0 Holliday junction DNA helicase ruvB N-terminus AAA_10 PF12846.2 KLO15884.1 - 0.019 14.4 0.2 0.26 10.6 0.1 2.5 2 0 0 2 2 2 0 AAA-like domain PhoH PF02562.11 KLO15884.1 - 0.019 14.1 0.0 0.038 13.2 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein AAA_19 PF13245.1 KLO15884.1 - 0.02 14.6 0.0 0.094 12.4 0.0 2.1 2 0 0 2 2 2 0 Part of AAA domain Sigma54_activ_2 PF14532.1 KLO15884.1 - 0.024 14.6 0.0 0.059 13.4 0.0 1.6 1 1 0 1 1 1 0 Sigma-54 interaction domain AAA_3 PF07726.6 KLO15884.1 - 0.025 14.1 0.0 0.79 9.3 0.0 2.3 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 KLO15884.1 - 0.044 13.2 0.0 0.14 11.6 0.0 1.8 2 0 0 2 2 2 0 Sigma-54 interaction domain NACHT PF05729.7 KLO15884.1 - 0.055 13.1 0.0 0.11 12.0 0.0 1.7 1 0 0 1 1 1 0 NACHT domain RNA_helicase PF00910.17 KLO15884.1 - 0.059 13.5 0.0 0.34 11.0 0.0 2.1 2 0 0 2 2 2 0 RNA helicase AAA_29 PF13555.1 KLO15884.1 - 0.091 12.3 0.1 0.25 10.9 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain TrwB_AAD_bind PF10412.4 KLO15884.1 - 0.097 11.2 0.0 0.2 10.2 0.0 1.4 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain AAA_18 PF13238.1 KLO15884.1 - 0.1 12.9 0.0 0.37 11.0 0.0 1.9 2 0 0 2 2 2 0 AAA domain SKI PF01202.17 KLO15884.1 - 0.1 12.4 0.0 0.18 11.6 0.0 1.4 1 0 0 1 1 1 0 Shikimate kinase AAA_25 PF13481.1 KLO15884.1 - 0.13 11.6 0.4 1.5 8.1 0.1 2.2 1 1 1 2 2 2 0 AAA domain Ran_BP1 PF00638.13 KLO15885.1 - 2.3e-51 172.9 1.2 3.6e-51 172.3 0.8 1.3 1 0 0 1 1 1 1 RanBP1 domain WH1 PF00568.18 KLO15885.1 - 0.00015 21.4 0.2 0.00042 20.0 0.2 1.7 1 1 0 1 1 1 1 WH1 domain DUF1681 PF07933.9 KLO15885.1 - 0.0007 19.2 0.2 0.0013 18.3 0.0 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF1681) DUF4051 PF13260.1 KLO15885.1 - 0.066 12.5 0.2 0.066 12.5 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF4051) EMP24_GP25L PF01105.19 KLO15886.1 - 5.7e-52 176.1 0.4 6.5e-52 175.9 0.3 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD STAT_alpha PF01017.15 KLO15886.1 - 0.097 12.3 0.1 0.15 11.7 0.0 1.3 1 0 0 1 1 1 0 STAT protein, all-alpha domain Kinesin PF00225.18 KLO15887.1 - 7.3e-106 353.6 0.0 1.2e-105 352.9 0.0 1.3 1 0 0 1 1 1 1 Kinesin motor domain DUF904 PF06005.7 KLO15887.1 - 1.6 9.0 8.9 0.3 11.3 1.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF904) DUF4337 PF14235.1 KLO15887.1 - 2.3 8.0 9.5 1.4 8.7 1.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4337) GrpE PF01025.14 KLO15887.1 - 2.8 7.4 12.5 1 8.9 0.9 2.4 2 0 0 2 2 2 0 GrpE DUF972 PF06156.8 KLO15887.1 - 2.9 8.2 7.2 2.5 8.4 1.7 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF972) DUF2968 PF11180.3 KLO15887.1 - 3.3 7.0 18.0 0.24 10.7 3.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2968) Nucleos_tra2_C PF07662.8 KLO15888.1 - 3.9e-68 229.0 6.1 3.9e-68 229.0 4.2 1.7 2 0 0 2 2 2 1 Na+ dependent nucleoside transporter C-terminus Nucleos_tra2_N PF01773.15 KLO15888.1 - 3e-17 62.7 2.8 3e-17 62.7 2.0 4.2 4 0 0 4 4 4 1 Na+ dependent nucleoside transporter N-terminus Gate PF07670.9 KLO15888.1 - 0.0012 18.7 6.9 0.0012 18.7 4.8 3.3 3 2 0 3 3 3 1 Nucleoside recognition Neuromodulin_N PF10580.4 KLO15888.1 - 0.24 11.0 0.5 0.42 10.3 0.4 1.3 1 0 0 1 1 1 0 Gap junction protein N-terminal region Amidohydro_4 PF13147.1 KLO15889.1 - 8.6e-09 35.8 0.0 1.1e-08 35.4 0.0 1.2 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_2 PF04909.9 KLO15889.1 - 3.9e-08 33.1 0.0 7.6e-08 32.2 0.0 1.5 1 1 0 1 1 1 1 Amidohydrolase Phage_GPO PF05929.6 KLO15891.1 - 0.055 12.7 1.2 0.091 11.9 0.8 1.3 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase Plasmid_RAQPRD PF09686.5 KLO15891.1 - 0.15 12.1 0.2 0.15 12.1 0.1 2.0 3 0 0 3 3 3 0 Plasmid protein of unknown function (Plasmid_RAQPRD) COG2 PF06148.6 KLO15891.1 - 1 9.2 4.5 2.6 7.9 2.0 2.4 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF1764 PF08576.5 KLO15893.1 - 7.5e-19 68.4 18.7 7.8e-19 68.3 2.3 2.2 1 1 1 2 2 2 2 Eukaryotic protein of unknown function (DUF1764) Lumazine_bd PF12870.2 KLO15893.1 - 0.38 10.8 11.2 0.13 12.3 5.1 1.8 1 1 1 2 2 2 0 Lumazine-binding domain CAF-1_p150 PF11600.3 KLO15893.1 - 0.39 10.0 19.7 0.49 9.7 13.6 1.0 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal AAR2 PF05282.6 KLO15893.1 - 5.4 5.8 9.3 6.6 5.5 6.4 1.2 1 0 0 1 1 1 0 AAR2 protein GAS2 PF02187.12 KLO15894.1 - 1.9e-08 33.9 0.0 4.6e-08 32.7 0.0 1.6 1 0 0 1 1 1 1 Growth-Arrest-Specific Protein 2 Domain DUF3053 PF11254.3 KLO15894.1 - 7.9 5.6 6.3 42 3.2 0.0 3.7 4 0 0 4 4 4 0 Protein of unknown function (DUF3053) DHO_dh PF01180.16 KLO15895.1 - 1.3e-91 306.6 0.0 1.6e-91 306.3 0.0 1.1 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase FMN_dh PF01070.13 KLO15895.1 - 0.0019 17.0 0.0 0.13 11.0 0.0 2.5 2 1 0 2 2 2 2 FMN-dependent dehydrogenase NMO PF03060.10 KLO15895.1 - 0.041 13.0 0.1 0.075 12.1 0.1 1.3 1 0 0 1 1 1 0 Nitronate monooxygenase ADH_N PF08240.7 KLO15896.1 - 3e-30 104.1 0.6 4.8e-30 103.5 0.4 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KLO15896.1 - 2.8e-22 78.6 0.0 4.7e-22 77.9 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 KLO15896.1 - 8.3e-05 23.4 0.1 0.00021 22.2 0.1 1.7 1 1 0 1 1 1 1 Zinc-binding dehydrogenase Methyltransf_18 PF12847.2 KLO15896.1 - 0.018 15.6 0.0 0.034 14.7 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain PrmA PF06325.8 KLO15896.1 - 0.033 13.2 0.1 0.047 12.8 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) UDPG_MGDP_dh_N PF03721.9 KLO15896.1 - 0.043 13.1 0.1 0.079 12.3 0.1 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Methyltransf_11 PF08241.7 KLO15896.1 - 0.075 13.5 0.0 0.2 12.1 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase domain 2-Hacid_dh_C PF02826.14 KLO15896.1 - 0.094 11.8 0.0 0.16 11.0 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Methyltransf_25 PF13649.1 KLO15896.1 - 0.11 12.9 0.0 0.2 12.0 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain EzrA PF06160.7 KLO15898.1 - 0.00027 19.2 0.9 0.00035 18.8 0.6 1.1 1 0 0 1 1 1 1 Septation ring formation regulator, EzrA Myosin_tail_1 PF01576.14 KLO15898.1 - 0.00069 17.4 2.3 0.00077 17.3 1.6 1.2 1 0 0 1 1 1 1 Myosin tail YscO PF07321.7 KLO15898.1 - 0.023 14.5 3.6 0.023 14.5 2.5 1.5 2 0 0 2 2 2 0 Type III secretion protein YscO APG6 PF04111.7 KLO15898.1 - 0.031 13.3 2.4 0.036 13.1 1.7 1.0 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF812 PF05667.6 KLO15898.1 - 0.035 12.6 0.5 0.053 12.0 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF812) PHZA_PHZB PF03284.8 KLO15898.1 - 0.079 12.0 0.3 0.1 11.7 0.2 1.2 1 0 0 1 1 1 0 Phenazine biosynthesis protein A/B IncA PF04156.9 KLO15898.1 - 0.12 11.9 2.3 0.18 11.4 1.6 1.2 1 0 0 1 1 1 0 IncA protein ADIP PF11559.3 KLO15898.1 - 0.75 9.6 8.7 0.05 13.5 2.0 1.7 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding CENP-Q PF13094.1 KLO15898.1 - 3.5 7.6 9.0 5 7.1 6.2 1.3 1 1 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit DUF904 PF06005.7 KLO15898.1 - 3.6 7.9 12.2 0.4 10.9 5.2 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF904) zf-RING_5 PF14634.1 KLO15899.1 - 1.2e-08 34.5 9.2 2.2e-08 33.6 6.4 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 KLO15899.1 - 6.4e-07 29.2 5.3 6.4e-07 29.2 3.7 2.0 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KLO15899.1 - 8.4e-07 28.7 9.5 1.2e-06 28.2 4.0 2.3 1 1 1 2 2 2 1 Ring finger domain zf-C3HC4_3 PF13920.1 KLO15899.1 - 0.00014 21.4 10.4 0.00096 18.7 7.2 2.1 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KLO15899.1 - 0.00026 20.5 10.6 0.0054 16.3 7.5 2.3 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 KLO15899.1 - 0.0079 16.2 5.6 0.0079 16.2 3.9 1.6 2 0 0 2 2 2 1 RING-H2 zinc finger zf-RING_UBOX PF13445.1 KLO15899.1 - 0.0097 15.6 0.7 0.0097 15.6 0.5 2.7 2 1 1 3 3 2 1 RING-type zinc-finger zf-RING_4 PF14570.1 KLO15899.1 - 0.018 14.5 5.2 0.02 14.5 2.9 1.7 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-P11 PF03854.9 KLO15899.1 - 0.022 14.2 4.9 0.042 13.3 3.4 1.5 1 1 0 1 1 1 0 P-11 zinc finger DUF1272 PF06906.6 KLO15899.1 - 0.022 14.5 6.4 0.038 13.8 4.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) DZR PF12773.2 KLO15899.1 - 0.025 14.3 4.5 0.059 13.2 3.1 1.7 1 1 0 1 1 1 0 Double zinc ribbon zf-RING_6 PF14835.1 KLO15899.1 - 0.026 14.3 5.8 0.026 14.3 4.1 1.8 2 1 0 2 2 1 0 zf-RING of BARD1-type protein zf-C3HC4_4 PF15227.1 KLO15899.1 - 0.034 14.0 11.1 0.076 12.9 3.1 3.3 2 1 2 4 4 3 0 zinc finger of C3HC4-type, RING DUF3279 PF11682.3 KLO15899.1 - 0.037 13.5 4.0 0.063 12.8 1.6 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3279) C1_4 PF07975.7 KLO15899.1 - 0.38 10.7 8.2 1.2 9.2 5.7 1.8 1 1 0 1 1 1 0 TFIIH C1-like domain Siva PF05458.7 KLO15899.1 - 1.1 8.7 4.7 1.7 8.1 3.2 1.2 1 0 0 1 1 1 0 Cd27 binding protein (Siva) TerY-C PF15616.1 KLO15899.1 - 1.6 8.6 7.3 0.7 9.8 3.1 1.8 2 0 0 2 2 2 0 TerY-C metal binding domain zinc-ribbons_6 PF07191.7 KLO15899.1 - 1.6 8.5 6.8 8.7 6.2 0.2 2.5 1 1 1 2 2 2 0 zinc-ribbons UPF0547 PF10571.4 KLO15899.1 - 3.4 7.4 7.6 1.4 8.6 1.1 2.5 2 0 0 2 2 2 0 Uncharacterised protein family UPF0547 Prok-RING_4 PF14447.1 KLO15899.1 - 4.4 6.9 12.6 1.3 8.6 3.1 2.8 2 1 1 3 3 3 0 Prokaryotic RING finger family 4 zf-MIZ PF02891.15 KLO15899.1 - 8.6 5.9 13.0 3 7.4 4.1 2.4 1 1 0 2 2 2 0 MIZ/SP-RING zinc finger Spindle_Spc25 PF08234.7 KLO15900.1 - 5.8e-18 64.6 0.0 3e-17 62.3 0.0 2.1 2 0 0 2 2 2 1 Chromosome segregation protein Spc25 Spc7 PF08317.6 KLO15900.1 - 0.00025 19.8 10.2 0.00033 19.4 7.1 1.2 1 0 0 1 1 1 1 Spc7 kinetochore protein ERM PF00769.14 KLO15900.1 - 0.0083 15.6 13.5 0.01 15.3 9.4 1.1 1 0 0 1 1 1 1 Ezrin/radixin/moesin family Filament PF00038.16 KLO15900.1 - 0.025 14.0 14.5 0.034 13.6 10.0 1.1 1 0 0 1 1 1 0 Intermediate filament protein TRIQK PF15168.1 KLO15900.1 - 0.026 14.4 2.2 1.1 9.1 0.0 3.0 2 1 0 2 2 2 0 Triple QxxK/R motif-containing protein family FlaC_arch PF05377.6 KLO15900.1 - 0.036 13.9 1.6 0.17 11.7 0.3 2.8 3 1 1 4 4 4 0 Flagella accessory protein C (FlaC) Golgin_A5 PF09787.4 KLO15900.1 - 0.038 12.5 14.2 0.048 12.1 9.8 1.1 1 0 0 1 1 1 0 Golgin subfamily A member 5 DUF1423 PF07227.6 KLO15900.1 - 0.21 10.1 12.3 0.28 9.8 8.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1423) TMCO5 PF14992.1 KLO15900.1 - 0.25 10.4 14.9 0.32 10.0 10.3 1.1 1 0 0 1 1 1 0 TMCO5 family FlgN PF05130.7 KLO15900.1 - 1.1 9.5 12.3 1.1 9.5 4.8 2.2 1 1 1 2 2 2 0 FlgN protein DUF342 PF03961.8 KLO15900.1 - 1.2 7.4 9.8 1.5 7.1 6.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF342) IncA PF04156.9 KLO15900.1 - 1.5 8.4 17.9 3.8 7.0 12.4 1.7 1 1 0 1 1 1 0 IncA protein HAUS6_N PF14661.1 KLO15900.1 - 1.6 8.0 9.0 2.6 7.3 6.2 1.4 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus APG6 PF04111.7 KLO15900.1 - 2.3 7.2 14.2 3.7 6.4 9.8 1.4 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF2422 PF10337.4 KLO15900.1 - 5.2 5.7 7.0 7.2 5.2 4.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2422) Mnd1 PF03962.10 KLO15900.1 - 6 6.4 15.1 13 5.3 10.5 1.6 1 1 0 1 1 1 0 Mnd1 family PA26 PF04636.8 KLO15900.1 - 6.2 5.3 8.1 7.8 5.0 5.6 1.1 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) Pkinase PF00069.20 KLO15901.1 - 2.6e-45 154.5 0.0 3.4e-45 154.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KLO15901.1 - 2.1e-23 82.7 0.0 2.8e-23 82.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KLO15901.1 - 0.00021 20.3 0.0 0.00056 18.9 0.0 1.7 1 0 0 1 1 1 1 Kinase-like Pox_ser-thr_kin PF05445.6 KLO15901.1 - 0.0074 15.1 0.0 0.011 14.5 0.0 1.2 1 0 0 1 1 1 1 Poxvirus serine/threonine protein kinase Kdo PF06293.9 KLO15901.1 - 0.0078 15.2 0.0 0.015 14.4 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KLO15901.1 - 0.0098 15.6 0.1 0.043 13.5 0.0 1.8 1 1 1 2 2 2 1 Phosphotransferase enzyme family WD40 PF00400.27 KLO15902.1 - 2.9e-12 45.9 14.2 0.0032 17.3 0.4 7.4 8 0 0 8 8 8 5 WD domain, G-beta repeat Lactonase PF10282.4 KLO15902.1 - 6.1e-06 25.5 0.0 0.049 12.7 0.0 2.3 1 1 1 2 2 2 2 Lactonase, 7-bladed beta-propeller DUF1777 PF08648.7 KLO15903.1 - 0.0023 17.7 48.0 0.0023 17.7 33.3 3.4 1 1 2 3 3 3 1 Protein of unknown function (DUF1777) DUF2594 PF10769.4 KLO15903.1 - 0.013 15.5 0.1 0.042 13.9 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2594) TMF_DNA_bd PF12329.3 KLO15903.1 - 6.5 6.6 15.4 0.63 9.8 0.1 3.1 3 1 0 3 3 3 0 TATA element modulatory factor 1 DNA binding Glyco_hydro_18 PF00704.23 KLO15905.1 - 1.4e-59 202.3 3.5 2.1e-59 201.7 2.4 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 FH2 PF02181.18 KLO15906.1 - 1.5e-85 287.3 0.0 1.5e-85 287.3 0.0 2.2 2 1 0 2 2 2 1 Formin Homology 2 Domain Drf_GBD PF06371.8 KLO15906.1 - 4.9e-26 91.2 0.3 4.9e-26 91.2 0.2 2.7 2 1 0 2 2 2 1 Diaphanous GTPase-binding Domain Drf_FH3 PF06367.11 KLO15906.1 - 2.3e-16 59.7 2.1 4.7e-16 58.7 0.0 2.4 2 1 1 3 3 3 1 Diaphanous FH3 Domain Acetyltransf_5 PF13444.1 KLO15907.1 - 2.4e-05 24.8 0.1 0.00036 21.0 0.1 2.2 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 KLO15907.1 - 8e-05 22.5 0.0 0.001 19.0 0.0 2.3 3 0 0 3 3 3 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 KLO15907.1 - 0.0003 20.8 0.0 0.00052 20.1 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 KLO15907.1 - 0.077 12.8 0.1 0.72 9.7 0.0 2.2 2 1 0 2 2 2 0 Acetyltransferase (GNAT) domain HMG_box_2 PF09011.5 KLO15908.1 - 1.7e-14 53.9 8.6 2.2e-07 31.1 0.6 2.5 2 0 0 2 2 2 2 HMG-box domain HMG_box PF00505.14 KLO15908.1 - 2.9e-14 53.0 11.8 4.2e-09 36.5 2.5 2.9 2 1 0 2 2 2 2 HMG (high mobility group) box DUF1289 PF06945.8 KLO15908.1 - 0.83 9.1 2.7 0.88 9.0 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1289) GRIM-19 PF06212.7 KLO15909.1 - 8.3e-32 109.6 0.0 9.8e-32 109.3 0.0 1.0 1 0 0 1 1 1 1 GRIM-19 protein DUF3545 PF12065.3 KLO15910.1 - 0.039 13.6 0.1 0.066 12.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3545) DUF465 PF04325.8 KLO15910.1 - 0.24 11.1 2.8 0.5 10.0 1.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF465) Prefoldin_2 PF01920.15 KLO15911.1 - 1.6e-20 72.8 1.2 2e-20 72.5 0.8 1.0 1 0 0 1 1 1 1 Prefoldin subunit Prefoldin PF02996.12 KLO15911.1 - 0.013 15.1 0.7 0.033 13.8 0.5 1.6 1 1 0 1 1 1 0 Prefoldin subunit HTH_Tnp_Tc5 PF03221.11 KLO15911.1 - 0.091 12.5 0.1 0.2 11.4 0.1 1.5 1 0 0 1 1 1 0 Tc5 transposase DNA-binding domain bZIP_1 PF00170.16 KLO15911.1 - 0.14 12.1 2.1 0.27 11.2 0.9 1.8 2 1 0 2 2 2 0 bZIP transcription factor DUF904 PF06005.7 KLO15911.1 - 0.21 11.8 4.7 0.27 11.5 3.3 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF904) Fer4 PF00037.22 KLO15912.1 - 2.8e-14 52.0 16.9 1.5e-08 33.8 3.1 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_7 PF12838.2 KLO15912.1 - 1.5e-12 47.6 10.7 2.5e-12 46.9 7.4 1.3 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_21 PF14697.1 KLO15912.1 - 4.3e-10 39.2 5.1 5.8e-05 22.8 0.3 2.2 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_10 PF13237.1 KLO15912.1 - 4.6e-10 39.1 22.7 3.4e-08 33.1 8.7 1.9 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_16 PF13484.1 KLO15912.1 - 4.6e-10 40.0 19.4 6.3e-07 30.0 7.5 2.2 1 1 1 2 2 2 2 4Fe-4S double cluster binding domain Fer4_9 PF13187.1 KLO15912.1 - 3.4e-09 36.8 11.2 6.4e-09 35.9 7.7 1.5 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_8 PF13183.1 KLO15912.1 - 1e-08 35.0 19.2 9.2e-06 25.6 7.8 2.2 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_2 PF12797.2 KLO15912.1 - 1.3e-08 34.2 14.7 6.3e-05 22.6 1.9 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_6 PF12837.2 KLO15912.1 - 6e-08 32.2 18.0 0.00065 19.4 3.4 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_4 PF12800.2 KLO15912.1 - 2.1e-06 27.5 12.1 0.00057 19.9 2.1 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_17 PF13534.1 KLO15912.1 - 2.3e-06 27.8 9.4 0.00021 21.5 7.3 2.4 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_18 PF13746.1 KLO15912.1 - 1.8e-05 25.0 9.5 0.02 15.2 0.7 2.4 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_13 PF13370.1 KLO15912.1 - 4.8e-05 23.6 10.2 0.024 15.0 0.2 2.5 2 0 0 2 2 2 2 4Fe-4S single cluster domain Fer4_15 PF13459.1 KLO15912.1 - 0.0029 18.1 12.7 0.28 11.7 1.2 2.6 2 1 0 2 2 2 2 4Fe-4S single cluster domain FA_desaturase PF00487.19 KLO15912.1 - 0.032 13.6 1.3 0.041 13.3 0.9 1.1 1 0 0 1 1 1 0 Fatty acid desaturase Fer4_3 PF12798.2 KLO15912.1 - 0.034 14.7 18.1 0.07 13.7 3.2 2.3 2 0 0 2 2 2 0 4Fe-4S binding domain c-SKI_SMAD_bind PF08782.5 KLO15912.1 - 0.073 13.2 4.4 0.15 12.2 0.3 2.2 1 1 1 2 2 2 0 c-SKI Smad4 binding domain ArfGap PF01412.13 KLO15913.1 - 8.6e-34 115.8 0.1 1.6e-33 114.9 0.1 1.4 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf DNA_mis_repair PF01119.14 KLO15914.1 - 1.9e-14 53.1 0.0 8.9e-07 28.3 0.0 2.4 2 0 0 2 2 2 2 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.1 KLO15914.1 - 3.1e-10 39.8 0.0 6.8e-10 38.7 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 KLO15914.1 - 2.6e-05 23.8 0.0 8e-05 22.3 0.0 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase MutL_C PF08676.6 KLO15914.1 - 6.1e-05 22.6 0.0 0.00059 19.4 0.0 2.4 2 0 0 2 2 2 1 MutL C terminal dimerisation domain SBDS PF01172.13 KLO15915.1 - 2.8e-05 23.8 0.1 3.6e-05 23.4 0.1 1.2 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein IU_nuc_hydro PF01156.14 KLO15916.1 - 9.8e-94 314.0 0.0 1.1e-93 313.8 0.0 1.0 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase DUF202 PF02656.10 KLO15917.1 - 2.9e-13 49.8 1.9 2.9e-13 49.8 1.3 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF202) PepSY_TM_2 PF13703.1 KLO15917.1 - 0.76 9.9 4.6 1.8 8.7 3.2 1.7 1 1 0 1 1 1 0 PepSY-associated TM helix Myb_DNA-bind_6 PF13921.1 KLO15919.1 - 4e-05 23.6 0.1 0.00015 21.8 0.0 2.0 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 KLO15919.1 - 0.00025 21.0 0.0 0.0016 18.4 0.0 2.3 2 0 0 2 2 2 1 Myb-like DNA-binding domain Ribosomal_L11_N PF03946.9 KLO15919.1 - 0.1 12.0 0.0 0.23 10.9 0.0 1.5 1 0 0 1 1 1 0 Ribosomal protein L11, N-terminal domain Glypican PF01153.14 KLO15919.1 - 0.81 8.2 4.3 1.2 7.6 3.0 1.2 1 0 0 1 1 1 0 Glypican APG6 PF04111.7 KLO15919.1 - 1.2 8.1 7.0 0.093 11.7 0.4 2.0 2 0 0 2 2 2 0 Autophagy protein Apg6 RhoGEF PF00621.15 KLO15923.1 - 0.0007 19.5 0.0 0.0011 18.9 0.0 1.2 1 0 0 1 1 1 1 RhoGEF domain SARA PF11409.3 KLO15923.1 - 5.6 6.9 8.4 2.6 8.0 1.5 3.0 2 0 0 2 2 2 0 Smad anchor for receptor activation (SARA) RhoGEF PF00621.15 KLO15924.1 - 3.6e-11 43.2 0.0 6.7e-11 42.3 0.0 1.4 1 0 0 1 1 1 1 RhoGEF domain p450 PF00067.17 KLO15926.1 - 2.2e-65 220.9 0.0 2.8e-65 220.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Vac14_Fig4_bd PF11916.3 KLO15927.1 - 0.056 12.5 1.0 0.13 11.3 0.0 1.9 2 0 0 2 2 2 0 Vacuolar protein 14 C-terminal Fig4p binding CHCH PF06747.8 KLO15928.1 - 7.5e-05 22.5 7.3 0.0099 15.7 0.0 3.3 3 0 0 3 3 3 2 CHCH domain Pet191_N PF10203.4 KLO15928.1 - 0.011 15.8 4.0 0.011 15.8 2.8 2.1 2 0 0 2 2 2 0 Cytochrome c oxidase assembly protein PET191 COX6B PF02297.12 KLO15928.1 - 9.8 6.2 9.7 4 7.5 2.5 2.5 1 1 1 2 2 2 0 Cytochrome oxidase c subunit VIb BPL_LplA_LipB PF03099.14 KLO15929.1 - 2.2e-19 69.6 0.0 3.1e-19 69.2 0.0 1.2 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family F-box-like PF12937.2 KLO15930.1 - 0.018 14.7 0.3 0.042 13.5 0.0 1.8 2 0 0 2 2 2 0 F-box-like Glyco_hydro_20 PF00728.17 KLO15933.1 - 2.3e-83 280.2 0.0 2.7e-83 280.0 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Glycohydro_20b2 PF14845.1 KLO15933.1 - 1.5e-12 48.2 0.1 4.5e-12 46.7 0.0 1.8 2 0 0 2 2 2 1 beta-acetyl hexosaminidase like Glyco_hydro_20b PF02838.10 KLO15933.1 - 3.3e-07 30.8 0.0 9.9e-07 29.3 0.0 1.9 1 1 0 1 1 1 1 Glycosyl hydrolase family 20, domain 2 WD40 PF00400.27 KLO15934.1 - 7.1e-07 28.8 0.4 0.0092 15.8 0.0 4.5 6 0 0 6 6 6 2 WD domain, G-beta repeat F-box-like PF12937.2 KLO15935.1 - 8.9e-06 25.3 3.1 8.9e-06 25.3 2.1 2.6 2 1 0 2 2 2 1 F-box-like DUF3216 PF11505.3 KLO15935.1 - 0.0014 18.4 0.0 0.0028 17.4 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3216) F-box PF00646.28 KLO15935.1 - 0.24 11.0 8.1 0.051 13.2 1.9 2.8 2 1 0 2 2 2 0 F-box domain F-box-like PF12937.2 KLO15936.1 - 0.00033 20.3 0.1 0.00076 19.1 0.0 1.6 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.2 KLO15936.1 - 0.55 9.9 6.6 36 4.1 0.7 4.7 3 1 1 5 5 5 0 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KLO15936.1 - 1.2 8.9 10.8 0.96 9.2 0.7 4.2 3 1 1 4 4 4 0 Leucine rich repeat LRR_6 PF13516.1 KLO15936.1 - 4.5 7.6 5.9 24 5.3 0.0 4.3 5 0 0 5 5 5 0 Leucine Rich repeat Dynamin_N PF00350.18 KLO15937.1 - 1.2e-17 64.2 0.0 1.2e-17 64.2 0.0 2.7 3 0 0 3 3 3 1 Dynamin family MMR_HSR1 PF01926.18 KLO15937.1 - 1.8e-11 44.0 0.0 8.1e-11 41.9 0.0 2.2 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 KLO15937.1 - 6.5e-09 35.4 0.1 1.2e-07 31.4 0.1 2.4 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Miro PF08477.8 KLO15937.1 - 6.8e-05 23.3 0.2 0.0076 16.7 0.0 2.9 1 1 1 2 2 2 1 Miro-like protein AAA_29 PF13555.1 KLO15937.1 - 0.0012 18.3 0.0 0.003 17.0 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain cobW PF02492.14 KLO15937.1 - 0.0095 15.3 1.8 0.11 11.8 0.3 2.7 2 1 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain Arf PF00025.16 KLO15937.1 - 0.029 13.5 0.1 1.5 7.9 0.0 2.7 2 0 0 2 2 2 0 ADP-ribosylation factor family FtsK_SpoIIIE PF01580.13 KLO15937.1 - 0.034 13.6 1.1 3 7.2 0.0 2.4 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_17 PF13207.1 KLO15937.1 - 0.035 14.9 0.0 9.3 7.0 0.0 3.7 3 1 0 3 3 3 0 AAA domain Septin PF00735.13 KLO15937.1 - 0.037 13.0 0.4 0.07 12.1 0.0 1.6 2 0 0 2 2 2 0 Septin PduV-EutP PF10662.4 KLO15937.1 - 0.039 13.4 0.0 7.6 6.0 0.0 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation FeoB_N PF02421.13 KLO15937.1 - 0.043 13.0 0.0 0.58 9.4 0.0 2.2 2 0 0 2 2 2 0 Ferrous iron transport protein B DUF258 PF03193.11 KLO15937.1 - 0.044 12.9 0.1 0.27 10.3 0.1 2.2 1 1 0 1 1 1 0 Protein of unknown function, DUF258 Lipase_GDSL PF00657.17 KLO15938.1 - 7.9e-18 65.1 0.0 1.1e-17 64.6 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.1 KLO15938.1 - 0.00013 22.2 1.1 0.00023 21.3 0.7 1.5 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family F-box-like PF12937.2 KLO15939.1 - 1.2e-05 24.9 0.4 3.9e-05 23.2 0.2 2.1 2 0 0 2 2 2 1 F-box-like LRR_4 PF12799.2 KLO15939.1 - 0.0011 18.5 3.9 6.8 6.4 0.2 4.8 7 0 0 7 7 7 2 Leucine Rich repeats (2 copies) BSD PF03909.12 KLO15939.1 - 0.015 15.0 0.1 0.65 9.7 0.1 2.4 2 0 0 2 2 2 0 BSD domain MIP PF00230.15 KLO15940.1 - 7e-44 149.9 10.3 8.9e-44 149.6 7.1 1.0 1 0 0 1 1 1 1 Major intrinsic protein 2TM PF13239.1 KLO15940.1 - 2.4 8.2 10.3 0.21 11.6 0.7 2.8 3 0 0 3 3 3 0 2TM domain F-box PF00646.28 KLO15941.1 - 4e-06 26.3 0.7 4e-06 26.3 0.5 2.2 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.2 KLO15941.1 - 0.012 15.2 0.6 0.05 13.3 0.1 2.1 2 0 0 2 2 2 0 F-box-like WD40 PF00400.27 KLO15941.1 - 0.013 15.4 0.8 0.74 9.8 0.0 3.2 3 0 0 3 3 3 0 WD domain, G-beta repeat Acetate_kinase PF00871.12 KLO15942.1 - 3.8e-89 298.9 0.0 7.6e-89 297.9 0.0 1.5 1 1 0 1 1 1 1 Acetokinase family HAT PF02184.11 KLO15944.1 - 1.8e-24 85.1 52.5 9e-07 28.5 1.9 12.9 13 1 0 13 13 13 6 HAT (Half-A-TPR) repeat TPR_14 PF13428.1 KLO15944.1 - 2.8e-16 58.5 33.3 0.061 13.9 0.2 12.2 5 3 8 13 13 13 6 Tetratricopeptide repeat TPR_19 PF14559.1 KLO15944.1 - 2.4e-12 47.0 4.7 0.17 12.2 0.0 7.0 5 2 1 7 7 7 2 Tetratricopeptide repeat Suf PF05843.9 KLO15944.1 - 3.6e-10 40.0 17.8 0.0031 17.2 0.2 6.1 4 3 1 5 5 5 3 Suppressor of forked protein (Suf) TPR_17 PF13431.1 KLO15944.1 - 2.3e-07 30.4 1.4 0.015 15.4 0.0 5.1 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_12 PF13424.1 KLO15944.1 - 2.8e-06 27.1 14.7 0.041 13.8 0.0 6.5 7 1 2 9 9 8 2 Tetratricopeptide repeat TPR_2 PF07719.12 KLO15944.1 - 3.3e-06 26.5 8.3 2 8.5 0.0 7.8 9 0 0 9 9 9 2 Tetratricopeptide repeat TPR_16 PF13432.1 KLO15944.1 - 3.9e-05 24.2 39.7 0.00049 20.6 0.0 9.6 8 3 4 12 12 11 2 Tetratricopeptide repeat TPR_11 PF13414.1 KLO15944.1 - 9.7e-05 21.9 5.2 0.087 12.4 0.2 5.0 4 1 0 4 4 4 1 TPR repeat TPR_7 PF13176.1 KLO15944.1 - 0.00019 21.0 8.8 0.42 10.5 0.1 6.7 8 0 0 8 8 7 1 Tetratricopeptide repeat U3_assoc_6 PF08640.6 KLO15944.1 - 0.00073 19.2 11.7 0.18 11.5 0.4 5.4 4 3 1 5 5 5 2 U3 small nucleolar RNA-associated protein 6 Fis1_TPR_C PF14853.1 KLO15944.1 - 0.002 17.9 2.4 0.85 9.5 0.0 4.3 4 0 0 4 4 4 1 Fis1 C-terminal tetratricopeptide repeat TPR_1 PF00515.23 KLO15944.1 - 0.008 15.7 4.2 27 4.5 0.0 5.7 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_15 PF13429.1 KLO15944.1 - 0.013 14.6 24.9 0.49 9.4 0.2 5.6 3 2 3 6 6 6 0 Tetratricopeptide repeat TPR_8 PF13181.1 KLO15944.1 - 0.065 13.0 3.7 5.4 7.0 0.0 4.4 5 0 0 5 5 4 0 Tetratricopeptide repeat RasGEF PF00617.14 KLO15945.1 - 7.8e-51 172.4 0.0 1.3e-50 171.8 0.0 1.3 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.15 KLO15945.1 - 7.7e-20 70.9 0.0 1.8e-19 69.7 0.0 1.6 1 0 0 1 1 1 1 RasGEF N-terminal motif SH3_9 PF14604.1 KLO15945.1 - 8.2e-15 54.1 0.0 1.4e-14 53.3 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 KLO15945.1 - 1.8e-12 46.5 0.0 3.7e-12 45.5 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 KLO15945.1 - 1.4e-11 43.5 0.0 2.9e-11 42.5 0.0 1.6 1 0 0 1 1 1 1 SH3 domain WD40 PF00400.27 KLO15946.1 - 2.3e-05 24.1 0.3 0.9 9.5 0.0 3.7 3 0 0 3 3 3 2 WD domain, G-beta repeat F-box-like PF12937.2 KLO15946.1 - 0.021 14.5 0.1 0.061 13.0 0.1 1.7 1 0 0 1 1 1 0 F-box-like F-box PF00646.28 KLO15946.1 - 0.054 13.1 0.2 0.12 12.0 0.1 1.6 1 0 0 1 1 1 0 F-box domain ADH_zinc_N PF00107.21 KLO15947.1 - 3.1e-22 78.5 0.2 5.9e-22 77.5 0.2 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 KLO15947.1 - 7.1e-12 46.3 0.2 1.7e-11 45.0 0.0 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KLO15947.1 - 7.8e-11 41.7 4.2 8.2e-10 38.4 0.1 3.0 3 1 1 4 4 4 2 Alcohol dehydrogenase GroES-like domain Trehalase PF01204.13 KLO15949.1 - 1.1e-112 377.3 2.3 4.1e-101 339.1 0.0 2.0 2 0 0 2 2 2 2 Trehalase GDE_C PF06202.9 KLO15949.1 - 0.018 13.7 0.2 0.039 12.6 0.0 1.5 2 0 0 2 2 2 0 Amylo-alpha-1,6-glucosidase ELFV_dehydrog PF00208.16 KLO15950.1 - 3.7e-54 183.8 0.0 5.2e-54 183.4 0.0 1.2 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Bac_GDH PF05088.7 KLO15950.1 - 5.2e-20 70.6 0.0 1e-14 53.0 0.0 2.2 2 0 0 2 2 2 2 Bacterial NAD-glutamate dehydrogenase ELFV_dehydrog_N PF02812.13 KLO15950.1 - 0.0014 18.2 0.0 0.0034 16.9 0.0 1.6 1 1 0 1 1 1 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain Prenyltrans PF00432.16 KLO15951.1 - 1.2e-37 127.0 0.2 1e-10 41.0 0.2 5.4 5 0 0 5 5 5 5 Prenyltransferase and squalene oxidase repeat Prenyltrans_2 PF13249.1 KLO15951.1 - 9.3e-24 84.0 0.0 1e-11 45.2 0.0 3.8 1 1 3 4 4 4 3 Prenyltransferase-like Prenyltrans_1 PF13243.1 KLO15951.1 - 5.6e-10 39.1 0.0 7.2e-05 22.7 0.1 2.6 1 1 1 2 2 2 2 Prenyltransferase-like A2M_comp PF07678.9 KLO15951.1 - 0.066 12.4 0.2 0.96 8.6 0.0 2.6 2 1 0 3 3 3 0 A-macroglobulin complement component YkuD_2 PF13645.1 KLO15952.1 - 0.05 12.8 0.2 6.1 6.0 0.0 2.7 3 0 0 3 3 3 0 L,D-transpeptidase catalytic domain Filament_head PF04732.9 KLO15952.1 - 0.41 11.3 8.2 0.18 12.5 0.5 2.6 2 0 0 2 2 2 0 Intermediate filament head (DNA binding) region DUF2360 PF10152.4 KLO15952.1 - 1.5 9.1 12.8 1.2 9.3 2.6 2.3 2 0 0 2 2 2 0 Predicted coiled-coil domain-containing protein (DUF2360) Abhydrolase_5 PF12695.2 KLO15953.1 - 3.8e-05 23.4 0.0 0.00058 19.6 0.0 2.4 2 0 0 2 2 2 1 Alpha/beta hydrolase family DUF676 PF05057.9 KLO15953.1 - 0.0014 17.9 0.0 0.0024 17.1 0.0 1.2 1 0 0 1 1 1 1 Putative serine esterase (DUF676) PGAP1 PF07819.8 KLO15953.1 - 0.018 14.6 0.0 0.033 13.7 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein EamA PF00892.15 KLO15954.1 - 8.4e-25 87.2 30.6 3.3e-16 59.4 6.1 2.5 2 1 1 3 3 3 3 EamA-like transporter family EmrE PF13536.1 KLO15954.1 - 5.4e-05 23.3 28.6 0.00029 21.0 3.1 3.5 2 2 0 3 3 3 2 Multidrug resistance efflux transporter TPT PF03151.11 KLO15954.1 - 0.024 14.2 25.4 0.15 11.7 8.1 2.2 2 0 0 2 2 2 0 Triose-phosphate Transporter family Lipase_3 PF01764.20 KLO15955.1 - 3.2e-18 65.6 0.0 6e-18 64.8 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) DUF2974 PF11187.3 KLO15955.1 - 0.00057 19.3 0.2 0.016 14.5 0.1 2.3 1 1 0 1 1 1 1 Protein of unknown function (DUF2974) DUF900 PF05990.7 KLO15955.1 - 0.075 12.3 0.0 0.13 11.6 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) Mod_r PF07200.8 KLO15956.1 - 3.3e-25 88.7 5.1 1.1e-19 70.8 2.8 2.0 2 0 0 2 2 2 2 Modifier of rudimentary (Mod(r)) protein DUF3584 PF12128.3 KLO15956.1 - 0.0072 13.7 2.4 0.0096 13.3 1.6 1.2 1 1 0 1 1 1 1 Protein of unknown function (DUF3584) Hypoth_Ymh PF09509.5 KLO15956.1 - 0.045 13.3 0.6 0.084 12.5 0.4 1.6 1 1 0 1 1 1 0 Protein of unknown function (Hypoth_ymh) Herpes_TAF50 PF03326.8 KLO15956.1 - 0.061 12.2 0.4 0.076 11.9 0.3 1.0 1 0 0 1 1 1 0 Herpesvirus transcription activation factor (transactivator) COG6 PF06419.6 KLO15956.1 - 0.081 11.0 2.2 0.098 10.7 1.5 1.1 1 0 0 1 1 1 0 Conserved oligomeric complex COG6 Herpes_UL6 PF01763.11 KLO15956.1 - 0.13 10.4 0.3 0.13 10.3 0.2 1.1 1 0 0 1 1 1 0 Herpesvirus UL6 like F-box-like PF12937.2 KLO15957.1 - 4.2e-05 23.1 1.4 9.7e-05 22.0 0.9 1.7 1 0 0 1 1 1 1 F-box-like SelR PF01641.13 KLO15957.1 - 0.17 11.5 0.0 0.32 10.6 0.0 1.4 1 0 0 1 1 1 0 SelR domain LRR_6 PF13516.1 KLO15957.1 - 0.21 11.7 4.7 2.1 8.6 0.0 4.4 4 0 0 4 4 4 0 Leucine Rich repeat Glyco_hydro_61 PF03443.9 KLO15958.1 - 2e-69 233.7 0.2 2e-69 233.7 0.2 1.5 2 0 0 2 2 2 1 Glycosyl hydrolase family 61 CBM_1 PF00734.13 KLO15958.1 - 1.9e-12 46.6 5.1 5.1e-12 45.2 3.5 1.8 1 0 0 1 1 1 1 Fungal cellulose binding domain PLDc_N PF13396.1 KLO15959.1 - 0.027 14.1 1.7 0.15 11.7 1.2 2.4 1 0 0 1 1 1 0 Phospholipase_D-nuclease N-terminal Dpy19 PF10034.4 KLO15960.1 - 0.076 11.1 3.7 0.096 10.8 2.6 1.1 1 0 0 1 1 1 0 Q-cell neuroblast polarisation NCA2 PF08637.5 KLO15963.1 - 1.6e-77 260.2 0.0 2.5e-77 259.6 0.0 1.3 1 0 0 1 1 1 1 ATP synthase regulation protein NCA2 MIP PF00230.15 KLO15964.1 - 2.4e-51 174.3 5.9 2.9e-51 174.1 4.1 1.1 1 0 0 1 1 1 1 Major intrinsic protein PAP2 PF01569.16 KLO15964.1 - 3.3 7.4 11.1 0.27 10.9 1.3 2.8 2 2 0 2 2 2 0 PAP2 superfamily EamA PF00892.15 KLO15964.1 - 4.8 7.2 13.0 0.19 11.8 1.4 3.0 3 0 0 3 3 3 0 EamA-like transporter family F-box-like PF12937.2 KLO15965.1 - 9.1e-07 28.5 0.1 3.6e-06 26.6 0.1 2.0 1 0 0 1 1 1 1 F-box-like Sod_Cu PF00080.15 KLO15966.1 - 1.3e-47 161.5 1.6 1.5e-47 161.2 1.1 1.0 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) His_Phos_1 PF00300.17 KLO15967.1 - 1.3e-30 106.5 0.0 1.9e-30 106.0 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) CH PF00307.26 KLO15968.1 - 5.4e-43 145.4 0.1 1.4e-23 82.9 0.0 2.7 2 0 0 2 2 2 2 Calponin homology (CH) domain EFhand_Ca_insen PF08726.5 KLO15968.1 - 4.6e-17 61.7 0.0 1.7e-16 59.9 0.0 2.1 1 0 0 1 1 1 1 Ca2+ insensitive EF hand CAMSAP_CH PF11971.3 KLO15968.1 - 2.6e-12 46.1 0.2 2.3e-09 36.7 0.0 3.0 2 1 0 2 2 2 2 CAMSAP CH domain EF-hand_6 PF13405.1 KLO15968.1 - 0.0044 16.7 0.0 0.083 12.8 0.0 2.9 2 0 0 2 2 2 1 EF-hand domain MscS_porin PF12795.2 KLO15968.1 - 0.048 12.9 4.3 0.051 12.8 1.9 1.6 1 1 1 2 2 2 0 Mechanosensitive ion channel porin domain EF-hand_1 PF00036.27 KLO15968.1 - 0.056 12.7 0.1 0.31 10.4 0.0 2.4 2 0 0 2 2 2 0 EF hand EF-hand_7 PF13499.1 KLO15968.1 - 0.077 13.1 0.1 0.3 11.2 0.1 2.1 1 0 0 1 1 1 0 EF-hand domain pair Baculo_PEP_C PF04513.7 KLO15968.1 - 0.095 12.5 0.2 0.49 10.2 0.0 2.3 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF3407 PF11887.3 KLO15968.1 - 0.1 11.8 1.2 0.66 9.2 0.1 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3407) Ribosomal_L36e PF01158.13 KLO15968.1 - 0.12 12.3 0.0 0.24 11.3 0.0 1.5 1 0 0 1 1 1 0 Ribosomal protein L36e DUF221 PF02714.10 KLO15969.1 - 5.7e-46 156.8 18.5 2.8e-44 151.2 12.9 2.3 1 1 0 1 1 1 1 Domain of unknown function DUF221 RSN1_TM PF13967.1 KLO15969.1 - 1.4e-20 73.4 2.5 1.3e-19 70.3 1.7 2.6 2 0 0 2 2 2 1 Late exocytosis, associated with Golgi transport DUF4463 PF14703.1 KLO15969.1 - 1.7e-05 25.2 2.8 0.00099 19.5 0.1 3.5 2 1 0 2 2 2 1 Domain of unknown function (DUF4463) RRM_6 PF14259.1 KLO15969.1 - 0.016 15.2 0.0 0.36 10.8 0.0 2.4 2 0 0 2 2 2 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 KLO15969.1 - 0.038 13.6 0.0 3.2 7.4 0.0 2.7 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KLO15969.1 - 0.09 12.6 0.0 0.21 11.4 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Methyltransf_25 PF13649.1 KLO15970.1 - 3.2e-05 24.2 0.0 0.00014 22.1 0.0 2.1 2 1 0 2 2 2 1 Methyltransferase domain RasGEF PF00617.14 KLO15971.1 - 1.2e-14 54.4 0.1 5.8e-14 52.2 0.1 2.2 1 1 0 1 1 1 1 RasGEF domain DUF346 PF03984.8 KLO15971.1 - 0.027 13.9 1.3 0.066 12.6 0.9 1.7 1 0 0 1 1 1 0 Repeat of unknown function (DUF346) Eaf7 PF07904.8 KLO15972.1 - 1.9e-15 56.6 0.0 2.9e-15 55.9 0.0 1.3 1 0 0 1 1 1 1 Chromatin modification-related protein EAF7 Pkinase PF00069.20 KLO15973.1 - 1.9e-68 230.4 0.0 2.4e-68 230.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KLO15973.1 - 6.5e-29 100.7 0.0 8.9e-29 100.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.19 KLO15973.1 - 1.2e-07 32.1 0.8 3.1e-07 30.8 0.5 1.8 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.1 KLO15973.1 - 1.6e-06 27.2 0.0 3.8e-06 26.0 0.0 1.6 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 KLO15973.1 - 0.0089 15.1 0.0 0.014 14.4 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.15 KLO15973.1 - 0.023 14.2 0.1 0.037 13.5 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase APH PF01636.18 KLO15973.1 - 0.086 12.5 0.2 0.18 11.4 0.1 1.5 1 1 1 2 2 2 0 Phosphotransferase enzyme family DUF4504 PF14953.1 KLO15974.1 - 2.8e-05 23.5 0.0 5.8e-05 22.5 0.0 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF4504) Pro_isomerase PF00160.16 KLO15975.1 - 1.3e-48 165.1 0.1 3.1e-48 163.9 0.0 1.6 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD WD40 PF00400.27 KLO15975.1 - 1.2e-09 37.7 4.5 0.00033 20.4 0.0 4.1 4 0 0 4 4 4 2 WD domain, G-beta repeat Motile_Sperm PF00635.21 KLO15976.1 - 2.9e-26 91.2 0.9 4.7e-26 90.5 0.2 1.7 1 1 1 2 2 2 1 MSP (Major sperm protein) domain FixG_C PF11614.3 KLO15976.1 - 0.067 13.3 0.1 0.12 12.5 0.0 1.4 1 0 0 1 1 1 0 IG-like fold at C-terminal of FixG, putative oxidoreductase Lipase_GDSL PF00657.17 KLO15977.1 - 0.00041 20.2 0.3 0.0014 18.5 0.2 1.8 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase RICTOR_N PF14664.1 KLO15978.1 - 1.1e-86 290.7 1.9 1.9e-86 290.0 0.8 1.8 2 0 0 2 2 2 1 Rapamycin-insensitive companion of mTOR, N-term RICTOR_M PF14666.1 KLO15978.1 - 2.6e-74 249.0 1.5 2e-73 246.1 0.3 3.1 3 0 0 3 3 3 1 Rapamycin-insensitive companion of mTOR, middle domain RasGEF_N_2 PF14663.1 KLO15978.1 - 2e-33 114.7 0.1 9.5e-32 109.3 0.1 2.6 2 0 0 2 2 2 1 Rapamycin-insensitive companion of mTOR RasGEF_N domain RICTOR_V PF14668.1 KLO15978.1 - 8.6e-28 96.0 0.1 4.3e-25 87.4 0.0 4.1 4 0 0 4 4 4 1 Rapamycin-insensitive companion of mTOR, domain 5 HEAT_2 PF13646.1 KLO15978.1 - 3.6e-05 23.9 0.1 0.011 15.9 0.0 4.1 3 1 1 4 4 4 1 HEAT repeats Proteasom_PSMB PF10508.4 KLO15978.1 - 0.00062 18.1 1.4 0.19 9.9 0.0 3.7 3 1 1 4 4 4 1 Proteasome non-ATPase 26S subunit ETC_C1_NDUFA4 PF04800.7 KLO15979.1 - 8.9e-36 121.7 0.1 2.2e-35 120.5 0.1 1.5 2 0 0 2 2 2 1 ETC complex I subunit conserved region DUF3892 PF13031.1 KLO15979.1 - 0.03 14.7 0.1 0.1 13.0 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3892) TusA PF01206.12 KLO15979.1 - 0.061 12.9 0.0 3.4 7.3 0.0 2.3 2 0 0 2 2 2 0 Sulfurtransferase TusA Zn_clus PF00172.13 KLO15980.1 - 0.014 15.2 10.5 0.082 12.8 7.1 2.1 1 1 1 2 2 2 0 Fungal Zn(2)-Cys(6) binuclear cluster domain DEC-1_N PF04625.8 KLO15980.1 - 3 6.4 7.8 9.9 4.7 0.1 2.0 2 0 0 2 2 2 0 DEC-1 protein, N-terminal region Ribosomal_L22 PF00237.14 KLO15982.1 - 7.1e-32 109.4 0.0 1.2e-31 108.8 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e Peptidase_M74 PF03411.8 KLO15982.1 - 0.093 11.9 0.0 0.12 11.6 0.0 1.1 1 0 0 1 1 1 0 Penicillin-insensitive murein endopeptidase Terpene_synth_C PF03936.11 KLO15983.1 - 3.8e-11 42.7 0.0 4.2e-10 39.3 0.0 2.2 1 1 1 2 2 2 1 Terpene synthase family, metal binding domain Mito_carr PF00153.22 KLO15984.1 - 6.1e-42 141.2 6.7 4.5e-15 55.1 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein MutS_V PF00488.16 KLO15985.1 - 1.1e-54 185.3 0.0 2.7e-54 184.0 0.0 1.7 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 KLO15985.1 - 2e-36 125.7 0.4 2.8e-35 121.9 0.0 2.2 2 0 0 2 2 2 1 MutS domain III AAA_14 PF13173.1 KLO15985.1 - 0.036 13.9 0.0 0.092 12.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain DAP3 PF10236.4 KLO15985.1 - 0.044 12.7 0.6 0.53 9.1 0.0 2.2 2 0 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 Band_7 PF01145.20 KLO15986.1 - 7.8e-24 84.5 1.3 1.2e-23 83.8 0.9 1.3 1 0 0 1 1 1 1 SPFH domain / Band 7 family PQ-loop PF04193.9 KLO15987.1 - 1.1e-35 120.9 13.3 6.8e-20 70.3 0.8 2.8 3 0 0 3 3 3 2 PQ loop repeat CbtA PF09490.5 KLO15987.1 - 0.081 12.2 0.0 0.17 11.2 0.0 1.5 1 0 0 1 1 1 0 Probable cobalt transporter subunit (CbtA) F-box-like PF12937.2 KLO15988.1 - 5.9e-10 38.7 0.1 4e-09 36.0 0.0 2.4 2 0 0 2 2 2 1 F-box-like zf-MYND PF01753.13 KLO15989.1 - 6.9e-09 35.4 14.5 1.2e-08 34.6 10.0 1.4 1 0 0 1 1 1 1 MYND finger UCH_1 PF13423.1 KLO15989.1 - 0.076 12.4 0.0 0.12 11.8 0.0 1.3 1 0 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolase G-patch PF01585.18 KLO15990.1 - 8.3e-07 28.6 0.9 2.3e-05 24.0 0.4 2.4 2 0 0 2 2 2 1 G-patch domain zf-MYND PF01753.13 KLO15993.1 - 6.5e-08 32.3 18.7 1.4e-07 31.3 13.0 1.6 1 0 0 1 1 1 1 MYND finger Methyltransf_31 PF13847.1 KLO15994.1 - 2.7e-13 49.7 0.0 9.6e-13 47.9 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KLO15994.1 - 4.3e-12 46.0 0.0 6.6e-12 45.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KLO15994.1 - 5.2e-11 42.8 0.0 1.1e-10 41.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KLO15994.1 - 1.4e-10 40.6 0.0 3.6e-09 36.1 0.0 2.6 2 1 1 3 3 3 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.1 KLO15994.1 - 6.1e-08 32.9 0.0 1.6e-07 31.6 0.0 1.7 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KLO15994.1 - 4.2e-07 30.3 0.0 1.1e-06 28.9 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KLO15994.1 - 2.8e-05 24.6 0.0 0.00039 20.9 0.0 2.5 2 1 0 2 2 2 1 Methyltransferase domain TPMT PF05724.6 KLO15994.1 - 0.00025 20.5 0.0 0.00043 19.8 0.0 1.3 1 0 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) FtsJ PF01728.14 KLO15994.1 - 0.0054 16.7 0.0 0.033 14.1 0.0 1.9 1 1 0 2 2 2 1 FtsJ-like methyltransferase CheR PF01739.13 KLO15994.1 - 0.011 15.0 0.0 1 8.5 0.0 2.2 1 1 0 2 2 2 0 CheR methyltransferase, SAM binding domain Methyltransf_26 PF13659.1 KLO15994.1 - 0.013 15.5 0.0 0.13 12.2 0.0 2.1 1 1 0 1 1 1 0 Methyltransferase domain MTS PF05175.9 KLO15994.1 - 0.014 14.7 0.0 0.35 10.2 0.0 2.2 2 0 0 2 2 2 0 Methyltransferase small domain Methyltransf_4 PF02390.12 KLO15994.1 - 0.016 14.2 0.0 1.8 7.5 0.0 2.6 3 0 0 3 3 3 0 Putative methyltransferase PARP_reg PF02877.9 KLO15994.1 - 0.12 12.0 0.1 0.21 11.2 0.1 1.3 1 0 0 1 1 1 0 Poly(ADP-ribose) polymerase, regulatory domain SpoOE-like PF09388.5 KLO15995.1 - 0.062 12.8 0.1 0.11 12.0 0.1 1.4 1 0 0 1 1 1 0 Spo0E like sporulation regulatory protein ABC_membrane PF00664.18 KLO15998.1 - 5e-93 311.4 28.5 8.7e-50 169.6 5.6 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 KLO15998.1 - 4.2e-67 224.6 0.1 8.6e-33 113.5 0.0 3.0 3 0 0 3 3 3 2 ABC transporter SMC_N PF02463.14 KLO15998.1 - 3.9e-13 49.1 0.6 0.00024 20.3 0.0 4.0 3 1 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 KLO15998.1 - 1.6e-11 44.7 0.0 0.018 15.0 0.0 4.3 3 1 0 3 3 3 2 AAA domain ABC_ATPase PF09818.4 KLO15998.1 - 8.8e-09 34.4 0.3 0.0016 17.0 0.0 2.5 3 0 0 3 3 3 2 Predicted ATPase of the ABC class AAA_29 PF13555.1 KLO15998.1 - 1.4e-07 30.9 0.5 0.0015 17.9 0.1 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_17 PF13207.1 KLO15998.1 - 1.6e-06 28.9 0.0 0.14 12.9 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.1 KLO15998.1 - 8.8e-06 25.8 5.9 0.0077 16.2 0.1 3.2 3 1 0 3 3 3 2 AAA ATPase domain DUF258 PF03193.11 KLO15998.1 - 3.5e-05 23.0 0.0 0.17 11.0 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 G-alpha PF00503.15 KLO15998.1 - 6.9e-05 21.6 0.0 0.025 13.2 0.0 2.2 2 0 0 2 2 2 2 G-protein alpha subunit AAA_22 PF13401.1 KLO15998.1 - 0.0001 22.4 1.3 1.4 9.0 0.0 4.0 3 1 0 3 3 3 1 AAA domain AAA_30 PF13604.1 KLO15998.1 - 0.00027 20.6 0.1 4.3 6.8 0.0 3.9 4 0 0 4 4 4 0 AAA domain AAA_18 PF13238.1 KLO15998.1 - 0.00029 21.1 0.0 0.47 10.7 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.1 KLO15998.1 - 0.0003 20.2 0.0 0.39 10.0 0.0 3.0 3 0 0 3 3 3 1 AAA domain SbcCD_C PF13558.1 KLO15998.1 - 0.00032 20.5 3.0 0.29 11.0 0.2 3.3 2 2 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA PF00004.24 KLO15998.1 - 0.0009 19.4 0.5 24 5.1 0.0 4.2 3 1 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) DUF87 PF01935.12 KLO15998.1 - 0.0014 18.4 0.5 1.4 8.6 0.0 3.2 3 0 0 3 3 3 1 Domain of unknown function DUF87 AAA_23 PF13476.1 KLO15998.1 - 0.0018 18.6 0.0 3.9 7.7 0.0 2.8 3 0 0 3 3 2 1 AAA domain AAA_33 PF13671.1 KLO15998.1 - 0.0037 17.1 0.0 4 7.3 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.1 KLO15998.1 - 0.004 17.1 1.5 1.2 9.1 0.0 3.1 3 0 0 3 3 3 1 AAA domain AAA_5 PF07728.9 KLO15998.1 - 0.0049 16.6 0.5 5.4 6.7 0.0 3.3 4 0 0 4 4 3 0 AAA domain (dynein-related subfamily) AAA_14 PF13173.1 KLO15998.1 - 0.0092 15.8 0.1 6 6.7 0.0 3.6 4 0 0 4 4 4 0 AAA domain PRK PF00485.13 KLO15998.1 - 0.02 14.4 0.0 1.5 8.3 0.0 2.7 3 0 0 3 3 2 0 Phosphoribulokinase / Uridine kinase family APS_kinase PF01583.15 KLO15998.1 - 0.024 14.2 0.1 0.85 9.2 0.0 2.5 2 0 0 2 2 2 0 Adenylylsulphate kinase AAA_10 PF12846.2 KLO15998.1 - 0.027 13.8 0.6 11 5.3 0.0 3.1 3 0 0 3 3 3 0 AAA-like domain Zeta_toxin PF06414.7 KLO15998.1 - 0.033 13.3 0.1 4.5 6.3 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin MobB PF03205.9 KLO15998.1 - 0.037 13.7 0.1 13 5.4 0.0 2.7 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B RNA_helicase PF00910.17 KLO15998.1 - 0.051 13.7 0.0 6.9 6.9 0.0 3.1 3 0 0 3 3 2 0 RNA helicase Mg_chelatase PF01078.16 KLO15998.1 - 0.053 12.6 0.0 4.4 6.4 0.0 2.3 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI MMR_HSR1 PF01926.18 KLO15998.1 - 0.071 13.0 0.0 17 5.4 0.0 2.9 2 0 0 2 2 2 0 50S ribosome-binding GTPase ATP-synt_ab PF00006.20 KLO15998.1 - 0.089 12.2 0.0 7.8 5.9 0.0 2.7 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain Miro PF08477.8 KLO15998.1 - 0.1 13.1 0.1 23 5.5 0.0 2.9 3 0 0 3 3 2 0 Miro-like protein FtsK_SpoIIIE PF01580.13 KLO15998.1 - 0.11 11.9 0.0 7.4 5.9 0.0 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family NB-ARC PF00931.17 KLO15998.1 - 0.15 10.8 0.0 7.7 5.2 0.0 2.3 2 0 0 2 2 2 0 NB-ARC domain AAA_15 PF13175.1 KLO15998.1 - 0.56 9.1 0.0 29 3.5 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain Cofilin_ADF PF00241.15 KLO15999.1 - 1.9e-33 115.0 1.4 2.1e-33 114.8 0.9 1.0 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein zf-AN1 PF01428.11 KLO16000.1 - 1.6e-19 69.4 28.2 1.3e-10 40.9 5.8 2.7 3 0 0 3 3 3 2 AN1-like Zinc finger zinc_ribbon_6 PF14599.1 KLO16000.1 - 0.011 15.5 3.6 0.011 15.5 2.5 2.5 2 0 0 2 2 2 0 Zinc-ribbon Transp_Tc5_C PF04236.10 KLO16000.1 - 0.045 13.9 5.1 0.045 13.9 3.6 2.8 3 0 0 3 3 3 0 Tc5 transposase C-terminal domain LRR19-TM PF15176.1 KLO16000.1 - 2.3 7.9 4.0 15 5.3 0.6 2.4 2 0 0 2 2 2 0 Leucine-rich repeat family 19 TM domain Porin_3 PF01459.17 KLO16001.1 - 6.3e-52 176.5 2.9 8.8e-52 176.0 2.0 1.2 1 0 0 1 1 1 1 Eukaryotic porin DUF1510 PF07423.6 KLO16002.1 - 0.15 11.4 13.8 0.2 10.9 9.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) DDHD PF02862.12 KLO16002.1 - 3.3 7.4 6.5 4.4 7.0 4.5 1.3 1 0 0 1 1 1 0 DDHD domain Nop14 PF04147.7 KLO16002.1 - 7.2 4.3 20.6 8.4 4.1 14.3 1.0 1 0 0 1 1 1 0 Nop14-like family peroxidase PF00141.18 KLO16004.1 - 4.3e-28 98.3 0.0 7.1e-28 97.6 0.0 1.3 1 0 0 1 1 1 1 Peroxidase DUF3415 PF11895.3 KLO16004.1 - 1.8e-25 88.6 3.1 5e-25 87.1 1.9 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF3415) DUF627 PF04781.7 KLO16004.1 - 0.02 14.5 0.1 0.035 13.7 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF627) Cloacin_immun PF03513.9 KLO16004.1 - 0.15 12.1 0.0 0.31 11.1 0.0 1.5 1 0 0 1 1 1 0 Cloacin immunity protein peroxidase PF00141.18 KLO16005.1 - 3.1e-29 102.1 0.0 6.3e-29 101.1 0.0 1.5 1 1 0 1 1 1 1 Peroxidase DUF3415 PF11895.3 KLO16005.1 - 1.3e-25 89.0 2.4 5.9e-25 86.9 1.4 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF3415) DUF627 PF04781.7 KLO16005.1 - 0.059 12.9 0.0 0.097 12.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF627) TRP PF06011.7 KLO16006.1 - 0.05 12.1 0.0 0.065 11.8 0.0 1.1 1 0 0 1 1 1 0 Transient receptor potential (TRP) ion channel VIT1 PF01988.14 KLO16006.1 - 0.25 10.7 0.7 0.55 9.6 0.5 1.6 1 1 0 1 1 1 0 VIT family peroxidase PF00141.18 KLO16007.1 - 8e-28 97.4 0.0 1e-27 97.1 0.0 1.1 1 0 0 1 1 1 1 Peroxidase DUF3415 PF11895.3 KLO16007.1 - 4.4e-18 64.9 0.1 1.1e-17 63.7 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3415) HeH PF12949.2 KLO16008.1 - 3.6e-05 23.2 0.6 0.00017 21.0 0.3 2.2 2 0 0 2 2 2 1 HeH/LEM domain SAP PF02037.22 KLO16008.1 - 0.54 9.8 3.2 37 3.9 0.4 3.5 3 1 0 3 3 3 0 SAP domain NOGCT PF08155.6 KLO16009.1 - 1.1e-28 98.6 2.7 3.2e-28 97.1 1.8 1.8 1 0 0 1 1 1 1 NOGCT (NUC087) domain NOG1 PF06858.9 KLO16009.1 - 5.3e-28 96.6 0.1 1e-27 95.7 0.1 1.5 1 0 0 1 1 1 1 Nucleolar GTP-binding protein 1 (NOG1) MMR_HSR1 PF01926.18 KLO16009.1 - 5.8e-17 61.7 0.0 1.4e-16 60.4 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 KLO16009.1 - 2.1e-09 36.8 0.0 4.5e-09 35.7 0.0 1.6 1 1 0 1 1 1 1 Ferrous iron transport protein B Miro PF08477.8 KLO16009.1 - 0.00065 20.1 0.0 0.0019 18.6 0.0 1.9 1 0 0 1 1 1 1 Miro-like protein DUF258 PF03193.11 KLO16009.1 - 0.0046 16.1 0.0 0.048 12.8 0.0 2.4 1 1 0 1 1 1 1 Protein of unknown function, DUF258 GTP_EFTU PF00009.22 KLO16009.1 - 0.0052 16.2 0.1 0.048 13.1 0.1 2.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Dynamin_N PF00350.18 KLO16009.1 - 0.027 14.2 1.1 2.7 7.7 0.0 3.1 2 1 1 3 3 3 0 Dynamin family MobB PF03205.9 KLO16009.1 - 0.03 14.0 0.0 0.55 9.9 0.0 2.8 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AIG1 PF04548.11 KLO16009.1 - 0.054 12.5 0.0 0.17 10.9 0.0 2.0 1 0 0 1 1 1 0 AIG1 family Peptidase_M24 PF00557.19 KLO16010.1 - 1.2e-42 145.8 0.0 1.8e-42 145.2 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 Creatinase_N PF01321.13 KLO16010.1 - 3e-23 82.7 0.3 1.1e-20 74.4 0.0 3.0 3 1 0 3 3 3 2 Creatinase/Prolidase N-terminal domain DUF1233 PF06806.7 KLO16010.1 - 0.08 12.5 0.4 4.8 6.8 0.0 3.0 3 0 0 3 3 3 0 Putative excisionase (DUF1233) DUF4229 PF14012.1 KLO16013.1 - 0.11 12.4 0.4 0.26 11.1 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4229) NicO PF03824.11 KLO16013.1 - 0.17 11.1 0.1 0.3 10.3 0.1 1.3 1 0 0 1 1 1 0 High-affinity nickel-transport protein X PF00739.14 KLO16013.1 - 1.5 8.6 5.7 5.2 6.9 0.1 3.0 2 1 0 2 2 2 0 Trans-activation protein X zf-MYND PF01753.13 KLO16014.1 - 1.4e-08 34.4 9.0 3.4e-08 33.2 6.2 1.7 1 0 0 1 1 1 1 MYND finger Ecl1 PF12855.2 KLO16014.1 - 0.011 15.0 0.2 0.028 13.7 0.1 1.6 1 0 0 1 1 1 0 Life-span regulatory factor zf-RING_2 PF13639.1 KLO16016.1 - 3.5e-06 26.7 8.7 6.2e-06 25.9 6.1 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 KLO16016.1 - 2.6e-05 23.8 10.0 5.6e-05 22.7 6.9 1.6 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KLO16016.1 - 0.00032 20.3 9.8 0.0006 19.4 6.8 1.5 1 0 0 1 1 1 1 zinc-RING finger domain Baculo_IE-1 PF05290.6 KLO16016.1 - 0.0054 16.4 3.5 0.01 15.5 2.4 1.5 1 0 0 1 1 1 1 Baculovirus immediate-early protein (IE-0) zf-C3HC4_2 PF13923.1 KLO16016.1 - 0.0063 16.5 11.1 0.012 15.6 7.7 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KLO16016.1 - 0.0071 15.9 9.9 0.014 15.0 6.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.1 KLO16016.1 - 0.0097 15.4 9.9 0.034 13.6 6.9 1.8 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_4 PF14570.1 KLO16016.1 - 0.016 14.8 7.2 0.032 13.8 5.0 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain FYVE PF01363.16 KLO16016.1 - 0.021 14.7 1.7 0.05 13.4 1.2 1.7 1 0 0 1 1 1 0 FYVE zinc finger zf-RING_6 PF14835.1 KLO16016.1 - 0.95 9.2 6.0 2.1 8.2 4.2 1.5 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-MIZ PF02891.15 KLO16016.1 - 3.7 7.1 8.4 8.6 5.9 5.8 1.6 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger DUF4047 PF13256.1 KLO16016.1 - 7.3 6.5 9.6 4.9 7.1 4.7 2.1 2 1 1 3 3 3 0 Domain of unknown function (DUF4047) CorA PF01544.13 KLO16017.1 - 5.8e-30 104.3 5.8 1.6e-26 92.9 2.2 2.3 2 1 0 2 2 2 2 CorA-like Mg2+ transporter protein Ribosomal_60s PF00428.14 KLO16021.1 - 0.00016 22.0 0.6 0.00035 20.8 0.4 1.6 1 0 0 1 1 1 1 60s Acidic ribosomal protein Nucleoplasmin PF03066.10 KLO16021.1 - 0.041 13.4 3.8 0.07 12.6 2.6 1.3 1 0 0 1 1 1 0 Nucleoplasmin VirionAssem_T7 PF11653.3 KLO16021.1 - 0.4 11.4 3.2 0.79 10.5 2.2 1.4 1 0 0 1 1 1 0 Bacteriophage T7 virion assembly protein Sigma70_ner PF04546.8 KLO16021.1 - 0.45 10.1 5.6 0.66 9.5 3.9 1.2 1 0 0 1 1 1 0 Sigma-70, non-essential region NOA36 PF06524.7 KLO16021.1 - 2.8 7.1 5.4 4.5 6.4 3.8 1.2 1 0 0 1 1 1 0 NOA36 protein CENP-B_dimeris PF09026.5 KLO16021.1 - 5.6 7.2 11.0 10 6.4 7.6 1.4 1 0 0 1 1 1 0 Centromere protein B dimerisation domain PBP1_TM PF14812.1 KLO16021.1 - 7 7.0 8.4 12 6.2 5.8 1.3 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal F-box-like PF12937.2 KLO16023.1 - 8e-07 28.6 0.2 7.5e-06 25.5 0.1 2.6 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 KLO16023.1 - 1.8 8.2 7.9 2 8.1 1.7 3.3 2 1 0 2 2 2 0 F-box domain LRR_8 PF13855.1 KLO16023.1 - 3.2 7.5 10.6 0.6 9.8 0.4 4.3 3 1 2 5 5 5 0 Leucine rich repeat TMEM154 PF15102.1 KLO16024.1 - 0.021 14.5 0.1 0.048 13.3 0.0 1.6 2 0 0 2 2 2 0 TMEM154 protein family Herpes_gE PF02480.11 KLO16024.1 - 0.064 11.5 0.0 0.083 11.1 0.0 1.1 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E MGC-24 PF05283.6 KLO16024.1 - 1.1 9.0 7.4 0.31 10.8 3.0 1.6 2 0 0 2 2 2 0 Multi-glycosylated core protein 24 (MGC-24) DUF812 PF05667.6 KLO16025.1 - 0.013 14.0 1.7 0.014 13.8 1.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF812) Laminin_II PF06009.7 KLO16025.1 - 0.021 14.6 2.2 0.033 13.9 1.5 1.3 1 0 0 1 1 1 0 Laminin Domain II Bcr-Abl_Oligo PF09036.5 KLO16025.1 - 0.04 13.8 1.4 0.071 13.0 1.0 1.3 1 0 0 1 1 1 0 Bcr-Abl oncoprotein oligomerisation domain ATP-synt_B PF00430.13 KLO16025.1 - 0.072 12.8 8.6 0.11 12.3 5.9 1.2 1 0 0 1 1 1 0 ATP synthase B/B' CF(0) DUF2570 PF10828.3 KLO16025.1 - 1.2 8.7 4.2 1.8 8.1 2.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2570) Cytochrom_B561 PF03188.11 KLO16026.1 - 2.4e-08 33.9 0.4 4.9e-08 32.8 0.0 1.7 2 0 0 2 2 2 1 Eukaryotic cytochrome b561 DOMON PF03351.12 KLO16026.1 - 0.021 14.7 0.2 0.056 13.3 0.1 1.7 1 1 0 1 1 1 0 DOMON domain DUF2427 PF10348.4 KLO16026.1 - 0.2 11.2 3.9 0.22 11.1 0.9 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF2427) API5 PF05918.6 KLO16028.1 - 5.3e-16 58.2 0.6 6.3e-16 57.9 0.4 1.0 1 0 0 1 1 1 1 Apoptosis inhibitory protein 5 (API5) HEAT_2 PF13646.1 KLO16028.1 - 0.00022 21.4 0.2 0.00069 19.8 0.1 1.9 1 1 0 1 1 1 1 HEAT repeats Sigma54_CBD PF04963.8 KLO16028.1 - 0.038 13.4 0.0 0.088 12.2 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 factor, core binding domain FANCI_S1 PF14675.1 KLO16028.1 - 0.045 13.1 0.0 0.075 12.3 0.0 1.4 1 1 0 1 1 1 0 FANCI solenoid 1 HEAT PF02985.17 KLO16028.1 - 4.7 7.5 0.0 4.7 7.5 0.0 4.1 5 1 1 6 6 6 0 HEAT repeat FAD_binding_3 PF01494.14 KLO16029.1 - 6.5e-20 71.4 0.0 1.4e-19 70.3 0.0 1.6 1 1 0 1 1 1 1 FAD binding domain Lycopene_cycl PF05834.7 KLO16029.1 - 1.1e-09 37.7 0.6 0.00011 21.3 0.0 2.2 2 0 0 2 2 2 2 Lycopene cyclase protein Trp_halogenase PF04820.9 KLO16029.1 - 4.7e-09 35.3 4.2 0.00082 18.1 0.0 3.1 3 0 0 3 3 3 2 Tryptophan halogenase NAD_binding_8 PF13450.1 KLO16029.1 - 4.8e-07 29.7 0.8 1.1e-06 28.5 0.5 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 KLO16029.1 - 3.3e-05 22.9 3.2 0.00031 19.7 2.0 2.2 1 1 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 KLO16029.1 - 0.0001 21.3 2.0 0.0002 20.3 1.4 1.4 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.22 KLO16029.1 - 0.00058 20.2 0.3 0.0022 18.3 0.2 2.0 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 KLO16029.1 - 0.001 18.2 0.2 0.0017 17.4 0.1 1.3 1 0 0 1 1 1 1 Thi4 family HI0933_like PF03486.9 KLO16029.1 - 0.0014 17.1 0.9 0.0025 16.3 0.6 1.3 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox_2 PF07992.9 KLO16029.1 - 0.0029 17.4 1.0 0.0057 16.5 0.7 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 KLO16029.1 - 0.009 14.9 0.8 0.014 14.3 0.6 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A Amino_oxidase PF01593.19 KLO16029.1 - 0.01 14.9 1.4 0.45 9.5 0.1 2.2 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase NAD_binding_9 PF13454.1 KLO16029.1 - 0.019 14.7 0.2 7.3 6.3 0.4 2.7 2 0 0 2 2 2 0 FAD-NAD(P)-binding SE PF08491.5 KLO16029.1 - 0.061 12.1 0.0 0.25 10.1 0.0 1.8 2 0 0 2 2 2 0 Squalene epoxidase BRX PF08381.6 KLO16029.1 - 0.08 12.0 1.2 0.16 11.0 0.9 1.4 1 0 0 1 1 1 0 Transcription factor regulating root and shoot growth via Pin3 Asp PF00026.18 KLO16030.1 - 3.8e-64 216.9 3.7 4.7e-64 216.6 2.6 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 KLO16030.1 - 8.2e-06 25.8 5.2 1e-05 25.5 2.1 2.3 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 KLO16030.1 - 0.0004 20.8 1.8 0.037 14.5 0.3 3.0 2 1 0 2 2 2 1 Aspartyl protease TAXi_C PF14541.1 KLO16030.1 - 0.0096 15.4 0.1 0.11 11.9 0.1 2.3 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal Amidohydro_4 PF13147.1 KLO16031.1 - 1.1e-17 64.9 5.3 9.2e-15 55.3 0.1 4.1 2 2 0 2 2 2 2 Amidohydrolase Amidohydro_5 PF13594.1 KLO16031.1 - 2e-10 40.3 0.2 2e-10 40.3 0.1 2.5 3 0 0 3 3 3 1 Amidohydrolase Amidohydro_1 PF01979.15 KLO16031.1 - 1.1e-09 38.3 1.0 2.2e-07 30.8 0.0 2.8 3 1 0 3 3 3 2 Amidohydrolase family Amidohydro_3 PF07969.6 KLO16031.1 - 4.2e-05 22.9 3.7 0.0016 17.6 0.0 3.5 4 0 0 4 4 4 2 Amidohydrolase family Pkinase PF00069.20 KLO16032.1 - 8.2e-69 231.6 0.0 1.1e-68 231.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KLO16032.1 - 1.9e-37 128.7 0.0 2.4e-37 128.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.21 KLO16032.1 - 1.1e-16 60.6 0.6 2e-16 59.8 0.4 1.5 1 0 0 1 1 1 1 FHA domain Kinase-like PF14531.1 KLO16032.1 - 2.6e-07 29.8 0.0 1.3e-06 27.6 0.0 1.8 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 KLO16032.1 - 6.1e-07 29.4 0.2 0.022 14.4 0.0 3.5 3 1 1 4 4 4 2 Phosphotransferase enzyme family Kdo PF06293.9 KLO16032.1 - 1.1e-05 24.5 0.1 1.8e-05 23.8 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 KLO16032.1 - 0.05 12.9 0.0 0.098 12.0 0.0 1.4 1 0 0 1 1 1 0 RIO1 family Acyltransferase PF01553.16 KLO16033.1 - 5.4e-13 48.5 0.0 1e-12 47.6 0.0 1.5 1 0 0 1 1 1 1 Acyltransferase BTB PF00651.26 KLO16034.1 - 0.0017 18.3 0.0 0.0059 16.5 0.0 1.9 1 1 0 1 1 1 1 BTB/POZ domain DUF2618 PF10940.3 KLO16037.1 - 0.057 13.1 0.9 0.13 12.0 0.6 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2618) F-box-like PF12937.2 KLO16038.1 - 0.047 13.4 0.0 0.29 10.9 0.0 2.3 3 0 0 3 3 3 0 F-box-like Hist_deacetyl PF00850.14 KLO16042.1 - 4.4e-92 308.7 0.0 7.7e-92 307.8 0.0 1.4 1 0 0 1 1 1 1 Histone deacetylase domain Arb2 PF09757.4 KLO16042.1 - 4.3e-17 62.1 0.0 1.1e-16 60.7 0.0 1.7 1 0 0 1 1 1 1 Arb2 domain Abhydrolase_6 PF12697.2 KLO16042.1 - 0.017 14.9 0.0 0.039 13.8 0.0 1.6 1 0 0 1 1 1 0 Alpha/beta hydrolase family Fungal_trans PF04082.13 KLO16043.1 - 2.3e-10 39.7 0.0 4.4e-10 38.8 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KLO16043.1 - 1.7e-07 31.0 12.0 2.8e-07 30.3 8.3 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Copper-fist PF00649.13 KLO16043.1 - 0.01 14.9 1.8 0.01 14.9 1.2 2.0 2 0 0 2 2 2 0 Copper fist DNA binding domain TRP PF06011.7 KLO16045.1 - 4.6e-74 249.5 18.9 5.7e-74 249.2 13.1 1.0 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.1 KLO16045.1 - 1e-25 90.4 0.1 1.4e-25 89.9 0.1 1.2 1 0 0 1 1 1 1 ML-like domain Adeno_E3_CR2 PF02439.10 KLO16045.1 - 0.63 9.6 6.8 1.8 8.1 4.7 1.8 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 zf-MYND PF01753.13 KLO16048.1 - 1.9e-10 40.4 14.5 5.1e-10 39.0 10.0 1.8 1 0 0 1 1 1 1 MYND finger HMG_box PF00505.14 KLO16050.1 - 5.7e-08 32.9 2.6 1.5e-07 31.6 1.8 1.7 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 KLO16050.1 - 4e-07 30.2 2.3 1.3e-06 28.6 1.6 1.9 1 0 0 1 1 1 1 HMG-box domain SET PF00856.23 KLO16052.1 - 3.6e-26 92.3 2.3 8.3e-26 91.2 0.3 2.5 2 2 0 2 2 2 1 SET domain Pre-SET PF05033.11 KLO16052.1 - 1.3e-17 63.8 1.7 1.3e-17 63.8 1.2 2.3 2 1 0 2 2 2 1 Pre-SET motif OSCP PF00213.13 KLO16053.1 - 5.2e-40 137.1 1.0 6.1e-40 136.8 0.7 1.0 1 0 0 1 1 1 1 ATP synthase delta (OSCP) subunit Hexapep PF00132.19 KLO16055.1 - 9e-09 34.4 1.0 0.0002 20.6 0.1 2.6 1 1 1 2 2 2 2 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.2 KLO16055.1 - 1e-07 32.1 0.0 1.6e-07 31.5 0.0 1.2 1 0 0 1 1 1 1 MobA-like NTP transferase domain NTP_transferase PF00483.18 KLO16055.1 - 2.4e-07 30.2 0.0 3.7e-07 29.6 0.0 1.2 1 0 0 1 1 1 1 Nucleotidyl transferase NOA36 PF06524.7 KLO16055.1 - 0.31 10.2 8.8 0.42 9.8 6.1 1.2 1 0 0 1 1 1 0 NOA36 protein Daxx PF03344.10 KLO16055.1 - 2 6.8 18.6 2.8 6.3 12.9 1.2 1 0 0 1 1 1 0 Daxx Family CDC45 PF02724.9 KLO16055.1 - 2.5 6.0 13.9 3.2 5.6 9.7 1.1 1 0 0 1 1 1 0 CDC45-like protein MgsA_C PF12002.3 KLO16056.1 - 1.2e-58 197.5 0.0 1.9e-58 196.8 0.0 1.3 1 0 0 1 1 1 1 MgsA AAA+ ATPase C terminal RuvB_N PF05496.7 KLO16056.1 - 6.8e-17 61.3 0.0 1.5e-16 60.1 0.0 1.5 1 1 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA PF00004.24 KLO16056.1 - 1e-15 58.0 0.0 4.5e-15 56.0 0.0 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 KLO16056.1 - 1.1e-07 31.6 0.0 1.5e-06 28.0 0.0 2.3 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 KLO16056.1 - 2.7e-06 27.4 0.7 0.0038 17.2 0.0 3.2 2 1 1 3 3 3 1 AAA ATPase domain AAA_22 PF13401.1 KLO16056.1 - 5.7e-06 26.5 0.4 0.00045 20.3 0.0 2.9 2 1 1 3 3 2 1 AAA domain Sigma54_activat PF00158.21 KLO16056.1 - 6.4e-06 25.7 0.0 0.00067 19.1 0.0 2.3 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_14 PF13173.1 KLO16056.1 - 6.7e-06 26.0 0.0 1.6e-05 24.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.16 KLO16056.1 - 9.3e-06 24.9 0.0 0.071 12.2 0.0 2.4 1 1 1 2 2 2 2 Magnesium chelatase, subunit ChlI Sigma54_activ_2 PF14532.1 KLO16056.1 - 3.9e-05 23.7 0.0 9.7e-05 22.4 0.0 1.6 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA_17 PF13207.1 KLO16056.1 - 7e-05 23.6 0.0 0.00018 22.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 KLO16056.1 - 0.0003 21.0 0.0 0.00063 20.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.1 KLO16056.1 - 0.00036 20.5 0.0 0.00076 19.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 KLO16056.1 - 0.0013 18.5 0.0 0.0026 17.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.12 KLO16056.1 - 0.0026 17.2 0.0 0.0049 16.3 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein RNA_helicase PF00910.17 KLO16056.1 - 0.0035 17.4 0.0 0.012 15.8 0.0 1.9 1 0 0 1 1 1 1 RNA helicase AAA_10 PF12846.2 KLO16056.1 - 0.0044 16.4 0.0 0.43 9.9 0.0 2.9 3 0 0 3 3 3 1 AAA-like domain Zeta_toxin PF06414.7 KLO16056.1 - 0.0049 15.9 0.0 0.011 14.8 0.0 1.5 1 0 0 1 1 1 1 Zeta toxin AAA_2 PF07724.9 KLO16056.1 - 0.011 15.6 0.0 0.036 13.9 0.0 1.8 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) ABC_tran PF00005.22 KLO16056.1 - 0.013 15.8 0.0 0.042 14.1 0.0 1.9 1 0 0 1 1 1 0 ABC transporter KTI12 PF08433.5 KLO16056.1 - 0.013 14.7 0.0 0.96 8.5 0.0 3.0 3 0 0 3 3 3 0 Chromatin associated protein KTI12 Viral_helicase1 PF01443.13 KLO16056.1 - 0.019 14.4 0.0 0.039 13.4 0.0 1.5 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase DNA_pol3_delta2 PF13177.1 KLO16056.1 - 0.036 13.7 0.0 0.7 9.5 0.0 2.2 1 1 1 2 2 2 0 DNA polymerase III, delta subunit AAA_19 PF13245.1 KLO16056.1 - 0.044 13.5 0.0 0.15 11.8 0.0 1.9 1 0 0 1 1 1 0 Part of AAA domain NACHT PF05729.7 KLO16056.1 - 0.11 12.0 0.0 0.26 10.9 0.0 1.5 1 0 0 1 1 1 0 NACHT domain Rad17 PF03215.10 KLO16056.1 - 0.14 10.8 0.0 0.78 8.3 0.0 1.9 2 0 0 2 2 2 0 Rad17 cell cycle checkpoint protein AAA_25 PF13481.1 KLO16056.1 - 0.14 11.5 0.0 0.3 10.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_3 PF07726.6 KLO16056.1 - 0.16 11.5 0.0 0.43 10.1 0.0 1.8 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF258 PF03193.11 KLO16056.1 - 0.17 11.0 0.0 0.51 9.5 0.0 1.8 1 1 1 2 2 2 0 Protein of unknown function, DUF258 PduV-EutP PF10662.4 KLO16056.1 - 0.18 11.2 0.0 0.45 9.9 0.0 1.7 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation Parvo_NS1 PF01057.12 KLO16056.1 - 0.21 10.4 0.0 0.36 9.6 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 RAP1 PF07218.6 KLO16056.1 - 0.27 9.2 1.6 0.53 8.3 1.1 1.3 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) CRAL_TRIO PF00650.15 KLO16059.1 - 6.1e-10 38.8 0.0 1.1e-09 37.9 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain DUF2668 PF10873.3 KLO16060.1 - 0.00028 21.0 0.3 0.00037 20.6 0.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2668) SLAC1 PF03595.12 KLO16060.1 - 0.012 14.3 0.3 0.016 13.9 0.2 1.1 1 0 0 1 1 1 0 Voltage-dependent anion channel Herpes_gE PF02480.11 KLO16060.1 - 0.022 13.0 0.1 0.024 12.9 0.0 1.1 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E Amnionless PF14828.1 KLO16060.1 - 0.022 13.2 0.0 0.024 13.1 0.0 1.0 1 0 0 1 1 1 0 Amnionless UbiA PF01040.13 KLO16060.1 - 0.041 13.0 0.4 0.049 12.8 0.3 1.1 1 0 0 1 1 1 0 UbiA prenyltransferase family MARVEL PF01284.18 KLO16060.1 - 0.048 13.4 0.8 0.063 13.0 0.6 1.1 1 0 0 1 1 1 0 Membrane-associating domain DUF2062 PF09835.4 KLO16060.1 - 0.055 13.0 0.2 0.097 12.2 0.2 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2062) Yip1 PF04893.12 KLO16060.1 - 0.065 12.7 0.0 0.081 12.4 0.0 1.1 1 0 0 1 1 1 0 Yip1 domain DUF4436 PF14494.1 KLO16060.1 - 0.095 11.9 1.0 0.15 11.3 0.7 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4436) Mid2 PF04478.7 KLO16060.1 - 0.1 12.0 0.1 0.12 11.8 0.1 1.1 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor OppC_N PF12911.2 KLO16060.1 - 0.41 10.0 3.5 8.9 5.7 0.0 2.2 2 0 0 2 2 2 0 N-terminal TM domain of oligopeptide transport permease C DUF1656 PF07869.7 KLO16060.1 - 0.94 9.3 4.0 0.21 11.4 0.3 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1656) Peptidase_C15 PF01470.12 KLO16061.1 - 5.3e-05 23.1 0.0 0.063 13.1 0.0 2.3 2 0 0 2 2 2 2 Pyroglutamyl peptidase Acyl-CoA_dh_1 PF00441.19 KLO16062.1 - 6.1e-30 104.3 0.1 8.2e-30 103.8 0.1 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 KLO16062.1 - 7.8e-22 77.9 0.0 1.8e-21 76.8 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.14 KLO16062.1 - 2.2e-18 65.4 0.5 4.4e-18 64.5 0.4 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.6 KLO16062.1 - 0.0012 19.1 0.1 0.0018 18.5 0.0 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain OPT PF03169.10 KLO16064.1 - 4.4e-155 517.6 41.1 4.9e-155 517.4 28.5 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein DUF3093 PF11292.3 KLO16064.1 - 7.2 6.4 7.8 0.76 9.5 1.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3093) OPT PF03169.10 KLO16066.1 - 8.1e-158 526.6 38.9 9.2e-158 526.4 27.0 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein DUF3093 PF11292.3 KLO16066.1 - 0.0039 17.0 0.3 0.014 15.1 0.2 2.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3093) Fungal_trans PF04082.13 KLO16068.1 - 4.2e-12 45.4 0.0 1.3e-11 43.9 0.0 1.8 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KLO16068.1 - 9.3e-08 31.8 9.0 1.4e-07 31.2 6.2 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Surfac_D-trimer PF09006.6 KLO16068.1 - 0.22 11.2 0.8 2.2 8.0 0.0 2.5 2 0 0 2 2 2 0 Lung surfactant protein D coiled-coil trimerisation Fungal_trans PF04082.13 KLO16069.1 - 9.4e-13 47.6 0.1 1.4e-12 47.0 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KLO16069.1 - 7.2e-08 32.2 10.6 1.6e-07 31.1 7.3 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pyr_redox PF00070.22 KLO16071.1 - 7.6e-12 45.4 0.1 9.5e-10 38.7 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 KLO16071.1 - 5.2e-11 42.7 0.0 0.0095 15.8 0.0 4.3 3 1 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 KLO16071.1 - 1.5e-05 24.1 0.0 0.72 8.6 0.1 3.2 3 0 0 3 3 3 3 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 KLO16071.1 - 0.0059 16.6 0.0 16 5.4 0.0 3.2 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 KLO16071.1 - 0.13 11.1 0.0 0.33 9.8 0.0 1.6 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) Trp_halogenase PF04820.9 KLO16071.1 - 0.15 10.6 0.1 23 3.4 0.0 2.9 3 0 0 3 3 3 0 Tryptophan halogenase F-box-like PF12937.2 KLO16072.1 - 6.2e-06 25.8 0.2 4.4e-05 23.1 0.1 2.2 2 0 0 2 2 2 1 F-box-like Ribosomal_S2 PF00318.15 KLO16073.1 - 6.4e-43 146.4 0.0 1.8e-22 79.6 0.0 2.1 1 1 1 2 2 2 2 Ribosomal protein S2 DUF1793 PF08760.6 KLO16074.1 - 1.5e-13 51.0 0.0 3.2e-13 49.9 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1793) IncA PF04156.9 KLO16075.1 - 0.028 13.9 0.0 0.033 13.8 0.0 1.2 1 0 0 1 1 1 0 IncA protein Herpes_gE PF02480.11 KLO16075.1 - 0.033 12.4 0.0 0.034 12.4 0.0 1.1 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E PgaD PF13994.1 KLO16075.1 - 0.067 12.6 0.2 0.092 12.2 0.1 1.2 1 0 0 1 1 1 0 PgaD-like protein DUF872 PF05915.7 KLO16075.1 - 0.067 13.0 0.0 0.097 12.5 0.0 1.3 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF872) CD34_antigen PF06365.7 KLO16075.1 - 0.08 12.5 0.0 0.1 12.2 0.0 1.1 1 0 0 1 1 1 0 CD34/Podocalyxin family DUF4381 PF14316.1 KLO16075.1 - 0.098 12.7 0.5 0.15 12.1 0.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) DUF3328 PF11807.3 KLO16075.1 - 0.1 12.2 0.0 0.11 12.1 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3328) DUF1793 PF08760.6 KLO16076.1 - 1.1e-26 93.7 0.1 2e-26 92.8 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1793) YajC PF02699.10 KLO16076.1 - 0.32 10.7 0.8 0.75 9.5 0.6 1.6 1 0 0 1 1 1 0 Preprotein translocase subunit DUF3112 PF11309.3 KLO16077.1 - 1.6 8.4 10.1 3.1 7.5 6.9 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3112) Sorting_nexin PF03700.8 KLO16078.1 - 0.083 12.9 0.5 0.24 11.5 0.0 1.9 2 0 0 2 2 2 0 Sorting nexin, N-terminal domain SHMT PF00464.14 KLO16079.1 - 2e-173 576.3 0.0 2.4e-173 576.1 0.0 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Beta_elim_lyase PF01212.16 KLO16079.1 - 0.0018 17.4 0.0 0.0049 16.0 0.0 1.9 1 1 0 1 1 1 1 Beta-eliminating lyase SelA PF03841.8 KLO16079.1 - 0.093 11.4 0.0 0.18 10.5 0.0 1.4 1 0 0 1 1 1 0 L-seryl-tRNA selenium transferase BacteriocIIc_cy PF12173.3 KLO16082.1 - 0.12 12.3 1.6 11 6.1 0.1 2.3 2 0 0 2 2 2 0 Bacteriocin class IIc cyclic gassericin A-like RDD PF06271.7 KLO16082.1 - 3 7.7 8.9 6.7 6.6 6.2 1.6 1 1 0 1 1 1 0 RDD family Git3 PF11710.3 KLO16083.1 - 1.7e-07 31.0 6.5 3.8e-07 29.8 4.5 1.5 1 1 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 Dicty_CAR PF05462.6 KLO16083.1 - 0.008 15.1 2.1 0.014 14.3 1.4 1.3 1 0 0 1 1 1 1 Slime mold cyclic AMP receptor LRR_4 PF12799.2 KLO16084.1 - 2.6 7.7 4.3 18 5.0 0.1 4.0 5 1 0 5 5 5 0 Leucine Rich repeats (2 copies) F-box PF00646.28 KLO16088.1 - 0.0011 18.6 0.2 0.0025 17.4 0.1 1.6 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 KLO16088.1 - 0.0025 17.4 0.1 0.0055 16.3 0.1 1.6 1 0 0 1 1 1 1 F-box-like DUF3874 PF12990.2 KLO16089.1 - 0.053 13.6 0.0 0.12 12.4 0.0 1.6 1 0 0 1 1 1 0 Domain of unknonw function from B. Theta Gene description (DUF3874) DUF2628 PF10947.3 KLO16089.1 - 2.7 7.8 8.4 8.4 6.2 1.9 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF2628) AMP-binding PF00501.23 KLO16090.1 - 2.8e-72 243.4 0.0 4.5e-72 242.7 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme NAD_binding_4 PF07993.7 KLO16090.1 - 8.9e-69 231.1 0.0 8.7e-68 227.9 0.0 2.2 2 0 0 2 2 2 1 Male sterility protein PP-binding PF00550.20 KLO16090.1 - 1.5e-13 50.7 0.0 4e-13 49.4 0.0 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site AMP-binding_C PF13193.1 KLO16090.1 - 3.8e-10 40.5 0.0 2.2e-09 38.0 0.0 2.5 1 1 0 1 1 1 1 AMP-binding enzyme C-terminal domain Epimerase PF01370.16 KLO16090.1 - 8.7e-10 38.4 0.0 1.8e-09 37.4 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 KLO16090.1 - 0.0021 16.7 0.0 0.0098 14.6 0.0 2.0 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 KLO16090.1 - 0.033 14.1 0.1 2 8.4 0.0 3.1 3 0 0 3 3 3 0 NADH(P)-binding Condensation PF00668.15 KLO16090.1 - 0.29 9.9 0.7 0.65 8.7 0.0 1.8 3 0 0 3 3 3 0 Condensation domain YxiJ PF14176.1 KLO16091.1 - 0.061 13.4 0.1 0.12 12.4 0.0 1.4 1 0 0 1 1 1 0 YxiJ-like protein DUF2243 PF10002.4 KLO16091.1 - 0.093 12.5 3.6 2.4 7.9 1.1 2.2 2 0 0 2 2 2 0 Predicted membrane protein (DUF2243) DUF986 PF06173.7 KLO16091.1 - 0.88 9.3 5.7 0.83 9.4 0.9 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF986) Metallophos_2 PF12850.2 KLO16092.1 - 1.7e-18 66.9 0.0 2.2e-18 66.5 0.0 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.23 KLO16092.1 - 6.5e-06 25.6 1.2 0.074 12.4 0.2 2.2 2 0 0 2 2 2 2 Calcineurin-like phosphoesterase Phage_P2_GpU PF06995.6 KLO16092.1 - 0.042 13.2 0.0 0.079 12.3 0.0 1.4 1 0 0 1 1 1 0 Phage P2 GpU UPF0203 PF05254.7 KLO16093.1 - 2e-18 66.0 3.1 1.7e-17 62.9 2.1 1.9 1 1 0 1 1 1 1 Uncharacterised protein family (UPF0203) UCR_hinge PF02320.11 KLO16093.1 - 0.0025 17.6 3.2 1.1 9.2 0.4 2.2 2 0 0 2 2 2 2 Ubiquinol-cytochrome C reductase hinge protein Methyltrn_RNA_2 PF04013.7 KLO16093.1 - 0.047 13.2 0.0 0.058 12.9 0.0 1.1 1 0 0 1 1 1 0 Putative SAM-dependent RNA methyltransferase Arginosuc_synth PF00764.14 KLO16093.1 - 0.068 12.2 0.0 0.081 11.9 0.0 1.0 1 0 0 1 1 1 0 Arginosuccinate synthase Cmc1 PF08583.5 KLO16093.1 - 0.087 12.6 2.2 8.8 6.1 0.1 2.3 1 1 1 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like COX17 PF05051.8 KLO16093.1 - 0.17 11.9 1.2 2.1 8.4 0.2 2.1 2 0 0 2 2 2 0 Cytochrome C oxidase copper chaperone (COX17) COX6B PF02297.12 KLO16093.1 - 0.34 10.9 6.8 5.1 7.1 2.0 2.1 1 1 1 2 2 2 0 Cytochrome oxidase c subunit VIb ABC_membrane_2 PF06472.10 KLO16094.1 - 1.6e-81 273.5 0.2 2.2e-81 273.1 0.2 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region 2 ABC_tran PF00005.22 KLO16094.1 - 2.5e-13 50.5 0.0 6.4e-13 49.1 0.0 1.7 1 1 0 1 1 1 1 ABC transporter AAA_19 PF13245.1 KLO16094.1 - 0.00047 19.8 0.5 0.2 11.4 0.2 2.8 2 0 0 2 2 2 2 Part of AAA domain NACHT PF05729.7 KLO16094.1 - 0.022 14.4 0.0 0.052 13.2 0.0 1.7 1 0 0 1 1 1 0 NACHT domain AAA PF00004.24 KLO16094.1 - 0.12 12.5 0.0 0.32 11.1 0.0 1.8 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF605 PF04652.11 KLO16095.1 - 0.12 11.7 8.2 0.19 11.0 5.7 1.4 1 0 0 1 1 1 0 Vta1 like DUF3395 PF11875.3 KLO16096.1 - 6.1e-27 94.1 0.0 9.7e-27 93.4 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3395) DnaJ PF00226.26 KLO16096.1 - 4.2e-16 58.4 1.1 7.9e-16 57.5 0.8 1.5 1 0 0 1 1 1 1 DnaJ domain DUF244 PF03112.9 KLO16096.1 - 0.21 11.0 0.0 0.33 10.4 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized protein family (ORF7) DUF Gti1_Pac2 PF09729.4 KLO16098.1 - 1.9e-26 92.9 0.1 9.4e-23 80.9 0.1 2.1 1 1 1 2 2 2 2 Gti1/Pac2 family DUF1789 PF08748.6 KLO16098.1 - 0.14 12.2 0.0 0.31 11.1 0.0 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF1789) ADH_N PF08240.7 KLO16102.1 - 5.7e-32 109.7 3.1 9.9e-32 108.9 2.1 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KLO16102.1 - 1.3e-12 47.4 0.0 2.6e-12 46.4 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 KLO16102.1 - 8.6e-05 23.4 0.0 0.00029 21.7 0.0 1.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase FAD_binding_3 PF01494.14 KLO16102.1 - 0.00049 19.2 0.6 0.00072 18.7 0.4 1.2 1 0 0 1 1 1 1 FAD binding domain NAD_binding_3 PF03447.11 KLO16102.1 - 0.0041 17.4 0.0 0.012 15.9 0.0 1.8 2 0 0 2 2 2 1 Homoserine dehydrogenase, NAD binding domain Shikimate_DH PF01488.15 KLO16102.1 - 0.016 15.2 0.0 0.064 13.3 0.0 2.0 1 1 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase DUF2338 PF10100.4 KLO16102.1 - 0.077 11.3 0.0 0.11 10.8 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2338) NAD_binding_8 PF13450.1 KLO16102.1 - 0.21 11.6 0.8 0.63 10.1 0.3 2.0 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain His_Phos_2 PF00328.17 KLO16103.1 - 9.5e-27 94.2 0.0 1.7e-26 93.3 0.0 1.4 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Rad60-SLD_2 PF13881.1 KLO16103.1 - 0.12 12.2 0.0 0.27 11.1 0.0 1.6 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like Sec5 PF15469.1 KLO16105.1 - 8.9e-58 195.0 0.9 6.8e-57 192.1 0.2 2.6 3 0 0 3 3 3 1 Exocyst complex component Sec5 DUF2450 PF10475.4 KLO16105.1 - 0.015 14.2 0.6 0.051 12.4 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function N-terminal domain (DUF2450) Dioxygenase_C PF00775.16 KLO16106.1 - 7e-47 159.0 0.0 1e-46 158.4 0.0 1.2 1 0 0 1 1 1 1 Dioxygenase Dioxygenase_N PF04444.9 KLO16106.1 - 1.3e-11 44.2 0.0 2.4e-11 43.4 0.0 1.5 1 0 0 1 1 1 1 Catechol dioxygenase N terminus RE_ApaLI PF09499.5 KLO16106.1 - 0.033 13.5 0.0 0.049 12.9 0.0 1.2 1 0 0 1 1 1 0 ApaLI-like restriction endonuclease CarboxypepD_reg PF13620.1 KLO16106.1 - 0.057 13.4 1.4 0.18 11.8 0.2 2.4 3 0 0 3 3 3 0 Carboxypeptidase regulatory-like domain TauD PF02668.11 KLO16107.1 - 2.3e-55 188.0 0.2 3e-55 187.7 0.1 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family zf-NF-X1 PF01422.12 KLO16108.1 - 0.022 14.7 4.5 0.055 13.4 3.1 1.7 1 0 0 1 1 1 0 NF-X1 type zinc finger JTB PF05439.7 KLO16108.1 - 0.1 12.3 1.2 0.4 10.4 0.0 1.9 2 0 0 2 2 2 0 Jumping translocation breakpoint protein (JTB) SRP19 PF01922.12 KLO16109.1 - 2.6e-20 72.7 0.0 4e-20 72.1 0.0 1.3 1 0 0 1 1 1 1 SRP19 protein SSP160 PF06933.6 KLO16109.1 - 0.023 12.6 1.4 0.031 12.2 0.9 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 RAP1 PF07218.6 KLO16109.1 - 1.6 6.7 8.4 2.2 6.2 5.8 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Helitron_like_N PF14214.1 KLO16110.1 - 1.5e-42 145.4 0.1 6.8e-42 143.2 0.0 2.0 1 1 0 1 1 1 1 Helitron helicase-like domain at N-terminus Phage_GPA PF05840.8 KLO16110.1 - 0.028 13.1 0.0 0.041 12.5 0.0 1.2 1 0 0 1 1 1 0 Bacteriophage replication gene A protein (GPA) COesterase PF00135.23 KLO16112.1 - 1.9e-59 201.7 0.0 2.4e-55 188.2 0.0 2.1 2 0 0 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.8 KLO16112.1 - 0.00084 18.9 0.7 1.3 8.5 0.0 2.4 2 0 0 2 2 2 2 alpha/beta hydrolase fold PC_rep PF01851.17 KLO16113.1 - 1.5e-24 84.7 13.1 9.7e-05 22.3 0.1 8.8 8 0 0 8 8 8 5 Proteasome/cyclosome repeat Stn1_C PF12659.2 KLO16113.1 - 0.07 12.9 0.0 1.6 8.5 0.0 2.4 2 0 0 2 2 2 0 Telomere capping C-terminal wHTH Ank PF00023.25 KLO16113.1 - 0.094 12.5 0.0 0.24 11.2 0.0 1.7 1 0 0 1 1 1 0 Ankyrin repeat U79_P34 PF03064.11 KLO16113.1 - 1.5 8.2 6.8 2.6 7.4 4.7 1.3 1 0 0 1 1 1 0 HSV U79 / HCMV P34 AMP-binding PF00501.23 KLO16114.1 - 4.5e-86 288.8 0.0 6.7e-86 288.2 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 KLO16114.1 - 9.3e-07 29.7 0.0 3e-06 28.0 0.0 2.0 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain p450 PF00067.17 KLO16115.1 - 4.9e-55 186.8 0.0 6.2e-55 186.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 zf-C3HC4_3 PF13920.1 KLO16116.1 - 5e-06 26.0 8.3 7.9e-06 25.4 5.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) RRM_6 PF14259.1 KLO16116.1 - 7.2e-06 25.8 0.0 1.7e-05 24.6 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 KLO16116.1 - 1.8e-05 24.2 0.0 3.5e-05 23.3 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-RING_5 PF14634.1 KLO16116.1 - 0.00072 19.2 9.1 0.0014 18.3 6.3 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.20 KLO16116.1 - 0.0036 16.9 9.2 0.0065 16.1 6.4 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Metal_CEHH PF14455.1 KLO16116.1 - 0.0061 15.9 0.0 0.032 13.6 0.0 2.1 2 0 0 2 2 2 1 Predicted metal binding domain zf-RING_UBOX PF13445.1 KLO16116.1 - 0.0098 15.5 5.7 0.023 14.3 3.9 1.6 1 0 0 1 1 1 1 RING-type zinc-finger Prok-RING_4 PF14447.1 KLO16116.1 - 0.024 14.1 3.3 0.059 12.9 2.3 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.1 KLO16116.1 - 0.029 14.4 11.6 0.037 14.0 7.1 1.8 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KLO16116.1 - 0.031 14.0 11.2 0.019 14.7 6.1 1.9 2 0 0 2 2 2 0 Ring finger domain zf-RING_4 PF14570.1 KLO16116.1 - 0.075 12.6 0.3 0.14 11.7 0.2 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain G-alpha PF00503.15 KLO16117.1 - 3.1e-109 365.2 0.0 4.3e-109 364.7 0.0 1.1 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 KLO16117.1 - 2.6e-09 36.5 0.0 5e-06 25.8 0.0 2.4 2 0 0 2 2 2 2 ADP-ribosylation factor family AAA_29 PF13555.1 KLO16117.1 - 0.018 14.5 0.0 0.038 13.5 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF3416 PF11896.3 KLO16117.1 - 0.062 13.2 0.6 0.35 10.7 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3416) AAA_22 PF13401.1 KLO16117.1 - 0.079 13.0 0.0 0.6 10.2 0.0 2.3 2 0 0 2 2 2 0 AAA domain CBS PF00571.23 KLO16118.1 - 2.2e-08 33.7 0.0 0.0042 16.8 0.0 2.2 2 0 0 2 2 2 2 CBS domain HATPase_c_3 PF13589.1 KLO16119.1 - 2e-14 53.3 0.0 5.3e-14 52.0 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 KLO16119.1 - 2.3e-12 46.5 0.0 1.6e-10 40.6 0.0 2.3 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DNA_mis_repair PF01119.14 KLO16119.1 - 1.6e-10 40.4 0.8 3.8e-08 32.8 0.6 2.5 1 1 1 2 2 2 2 DNA mismatch repair protein, C-terminal domain MOR2-PAG1_N PF14222.1 KLO16120.1 - 4.9e-136 454.6 0.0 1.9e-135 452.6 0.0 1.9 2 0 0 2 2 2 1 Cell morphogenesis N-terminal MOR2-PAG1_C PF14225.1 KLO16120.1 - 7e-77 258.7 1.0 1.8e-76 257.3 0.7 1.7 1 0 0 1 1 1 1 Cell morphogenesis C-terminal MOR2-PAG1_mid PF14228.1 KLO16120.1 - 1.3e-15 56.1 0.3 1.5e-09 36.0 0.0 2.7 3 0 0 3 3 3 2 Cell morphogenesis central region PLAC8 PF04749.12 KLO16121.1 - 1.1e-11 45.2 5.1 1.4e-11 44.9 3.5 1.1 1 0 0 1 1 1 1 PLAC8 family RRM_1 PF00076.17 KLO16123.1 - 1.1e-15 56.9 0.0 3.3e-07 29.8 0.0 4.2 4 0 0 4 4 4 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KLO16123.1 - 1.8e-15 56.5 0.0 0.00015 21.4 0.0 4.7 4 0 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KLO16123.1 - 2.5e-12 46.5 0.0 0.0001 22.1 0.0 4.4 3 1 1 4 4 4 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) IBR PF01485.16 KLO16123.1 - 1.2e-10 41.1 23.4 9e-07 28.6 5.7 4.5 5 0 0 5 5 5 2 IBR domain zf-C3HC4 PF00097.20 KLO16123.1 - 4.1e-06 26.3 5.9 4.1e-06 26.3 4.1 4.6 3 1 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KLO16123.1 - 6.2e-06 26.1 5.8 6.2e-06 26.1 4.0 4.9 4 2 1 5 5 5 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 KLO16123.1 - 3.9e-05 23.4 6.5 3.9e-05 23.4 4.5 5.2 4 1 1 5 5 5 1 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.1 KLO16123.1 - 0.00025 20.8 5.7 0.00025 20.8 4.0 5.9 3 1 2 5 5 5 1 Ring finger domain UPF0175 PF03683.8 KLO16123.1 - 0.02 14.3 0.0 0.13 11.6 0.0 2.1 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0175) Nup35_RRM_2 PF14605.1 KLO16123.1 - 0.13 12.0 0.0 0.43 10.3 0.0 2.0 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif DUF2611 PF11022.3 KLO16124.1 - 2.2e-12 46.8 3.5 5.4e-12 45.6 2.4 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF2611) Pex26 PF07163.7 KLO16125.1 - 5.6 5.7 7.5 1.3 7.8 1.3 2.3 1 1 0 2 2 2 0 Pex26 protein AdoHcyase PF05221.12 KLO16126.1 - 1.5e-141 470.0 0.1 1.7e-141 469.8 0.0 1.0 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase AdoHcyase_NAD PF00670.16 KLO16126.1 - 6.4e-86 286.2 0.7 9.4e-86 285.6 0.5 1.2 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 2-Hacid_dh_C PF02826.14 KLO16126.1 - 1.3e-10 40.6 0.1 2.7e-10 39.6 0.0 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain IlvN PF07991.7 KLO16126.1 - 0.00016 21.0 0.1 0.00028 20.2 0.0 1.3 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain TrkA_N PF02254.13 KLO16126.1 - 0.0007 19.5 0.0 0.0015 18.5 0.0 1.6 1 0 0 1 1 1 1 TrkA-N domain ELFV_dehydrog PF00208.16 KLO16126.1 - 0.011 15.2 0.1 0.018 14.6 0.1 1.3 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase THF_DHG_CYH_C PF02882.14 KLO16126.1 - 0.036 13.1 0.2 0.38 9.8 0.2 2.6 3 1 0 3 3 3 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain DUF4448 PF14610.1 KLO16126.1 - 0.076 12.5 0.0 0.13 11.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) Shikimate_DH PF01488.15 KLO16126.1 - 0.099 12.7 0.3 0.25 11.4 0.2 1.6 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase GST_N PF02798.15 KLO16128.1 - 2.7e-08 33.8 0.0 4.4e-08 33.1 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 KLO16128.1 - 7e-05 22.7 0.0 0.00014 21.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 KLO16128.1 - 0.00014 22.0 0.0 0.00024 21.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 KLO16128.1 - 0.0013 19.2 0.0 0.0018 18.7 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 KLO16128.1 - 0.0051 16.6 0.0 0.0087 15.9 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Tht1 PF04163.7 KLO16129.1 - 5.1e-08 31.7 11.7 1.2e-07 30.5 8.1 1.5 1 1 0 1 1 1 1 Tht1-like nuclear fusion protein Apolipoprotein PF01442.13 KLO16129.1 - 0.022 14.2 5.2 0.14 11.6 3.6 2.1 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain HAUS-augmin3 PF14932.1 KLO16129.1 - 0.27 10.4 8.7 1.6 7.8 3.6 2.5 2 1 0 2 2 2 0 HAUS augmin-like complex subunit 3 Baculo_PEP_C PF04513.7 KLO16129.1 - 0.43 10.3 17.2 2.8 7.7 1.8 3.3 1 1 2 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus La PF05383.12 KLO16130.1 - 2.8e-21 75.0 0.1 4.2e-21 74.5 0.1 1.3 1 0 0 1 1 1 1 La domain HTH_Crp_2 PF13545.1 KLO16130.1 - 0.011 15.5 0.1 0.018 14.8 0.1 1.5 1 1 0 1 1 1 0 Crp-like helix-turn-helix domain DUF2186 PF09952.4 KLO16130.1 - 0.12 12.6 0.2 0.16 12.2 0.1 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2186) YihI PF04220.7 KLO16131.1 - 0.19 11.0 5.4 0.41 9.9 3.7 1.5 1 0 0 1 1 1 0 Der GTPase activator (YihI) Pkinase PF00069.20 KLO16133.1 - 1.4e-35 122.7 0.0 1.7e-35 122.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KLO16133.1 - 1.5e-13 50.3 0.0 2.1e-13 49.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KLO16133.1 - 0.013 14.4 0.0 0.017 14.0 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Choline_kinase PF01633.15 KLO16133.1 - 0.047 13.2 0.0 0.11 11.9 0.0 1.6 1 0 0 1 1 1 0 Choline/ethanolamine kinase MTBP_mid PF14919.1 KLO16133.1 - 0.12 10.9 0.1 0.2 10.3 0.1 1.2 1 0 0 1 1 1 0 MDM2-binding Pmp3 PF01679.12 KLO16134.1 - 6.1e-21 73.8 9.9 7.4e-21 73.5 6.9 1.1 1 0 0 1 1 1 1 Proteolipid membrane potential modulator PrgI PF12666.2 KLO16134.1 - 0.037 14.1 1.0 0.048 13.8 0.7 1.1 1 0 0 1 1 1 0 PrgI family protein DUF3816 PF12822.2 KLO16134.1 - 5.4 6.8 7.9 8.2 6.2 5.5 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3816) DCP1 PF06058.8 KLO16135.1 - 4.2e-19 68.7 0.0 6.6e-19 68.1 0.0 1.2 1 0 0 1 1 1 1 Dcp1-like decapping family PLAC8 PF04749.12 KLO16136.1 - 2.2e-21 76.4 11.9 2.7e-21 76.1 8.3 1.1 1 0 0 1 1 1 1 PLAC8 family PLAC8 PF04749.12 KLO16137.1 - 3.3e-22 79.0 21.2 4.1e-22 78.7 14.7 1.1 1 0 0 1 1 1 1 PLAC8 family adh_short PF00106.20 KLO16138.1 - 5.8e-11 42.5 0.0 1.4e-10 41.3 0.0 1.6 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KLO16138.1 - 4e-06 26.7 0.0 4.2e-06 26.6 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KLO16138.1 - 0.0034 17.0 0.0 0.005 16.5 0.0 1.2 1 0 0 1 1 1 1 KR domain NmrA PF05368.8 KLO16138.1 - 0.0076 15.5 0.3 0.02 14.1 0.0 1.7 3 0 0 3 3 3 1 NmrA-like family Lactococcin PF04369.8 KLO16138.1 - 0.091 12.7 0.0 0.24 11.3 0.0 1.7 1 0 0 1 1 1 0 Lactococcin-like family adh_short PF00106.20 KLO16139.1 - 5.3e-06 26.4 0.1 1.1e-05 25.4 0.0 1.6 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KLO16139.1 - 0.025 14.3 0.0 0.035 13.8 0.0 1.3 1 1 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase PLAC8 PF04749.12 KLO16140.1 - 4.9e-19 68.8 25.1 6.3e-19 68.5 17.4 1.1 1 0 0 1 1 1 1 PLAC8 family PLAC8 PF04749.12 KLO16141.1 - 1.3e-19 70.6 19.3 1.9e-19 70.1 13.4 1.2 1 0 0 1 1 1 1 PLAC8 family PLAC8 PF04749.12 KLO16142.1 - 2.4e-19 69.8 15.2 2.9e-19 69.5 10.5 1.1 1 0 0 1 1 1 1 PLAC8 family GPI-anchored PF10342.4 KLO16143.1 - 4.7e-06 26.9 1.1 4.7e-06 26.9 0.8 1.6 2 0 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family CD99L2 PF12301.3 KLO16143.1 - 0.00016 21.3 0.2 0.00022 20.9 0.2 1.1 1 0 0 1 1 1 1 CD99 antigen like protein 2 RAP1 PF07218.6 KLO16143.1 - 0.016 13.3 4.9 0.019 13.0 3.4 1.0 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) PAP1 PF08601.5 KLO16143.1 - 5.1 6.6 7.9 6.2 6.3 5.5 1.1 1 0 0 1 1 1 0 Transcription factor PAP1 MFS_1 PF07690.11 KLO16145.1 - 4.7e-27 94.6 31.7 1.7e-25 89.4 19.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 KLO16145.1 - 1.5e-10 40.0 13.3 7.9e-06 24.5 0.7 3.3 2 2 1 3 3 3 2 MFS/sugar transport protein Sugar_tr PF00083.19 KLO16145.1 - 3.5e-10 39.0 0.4 3.5e-10 39.0 0.3 2.5 3 0 0 3 3 3 1 Sugar (and other) transporter TRI12 PF06609.8 KLO16145.1 - 0.00049 18.4 0.9 0.00049 18.4 0.6 1.6 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) NAD_binding_1 PF00175.16 KLO16146.1 - 5.9e-25 87.9 0.0 9.2e-25 87.3 0.0 1.2 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.19 KLO16146.1 - 1.8e-14 53.6 0.0 3.8e-14 52.6 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.7 KLO16146.1 - 2.2e-06 27.6 0.3 0.00064 19.6 0.0 2.3 1 1 1 2 2 2 2 Ferric reductase NAD binding domain FAD_binding_9 PF08021.6 KLO16146.1 - 0.033 14.1 0.0 0.075 12.9 0.0 1.6 1 0 0 1 1 1 0 Siderophore-interacting FAD-binding domain DUF148 PF02520.12 KLO16146.1 - 0.066 13.0 0.0 0.78 9.5 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function DUF148 DUF2611 PF11022.3 KLO16146.1 - 0.067 13.2 0.0 0.2 11.7 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2611) eIF3g PF12353.3 KLO16147.1 - 2.3e-37 127.7 1.8 3.5e-37 127.1 1.3 1.3 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit G RRM_6 PF14259.1 KLO16147.1 - 7.8e-16 57.8 0.0 1.5e-15 56.9 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 KLO16147.1 - 9.8e-16 57.1 0.0 1.6e-15 56.4 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KLO16147.1 - 4.3e-08 32.8 0.1 1e-07 31.6 0.0 1.7 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF4651 PF15513.1 KLO16147.1 - 0.13 11.7 0.4 0.49 9.8 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4651) FMN_red PF03358.10 KLO16148.1 - 6.7e-10 38.6 0.0 9.2e-10 38.2 0.0 1.2 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.12 KLO16148.1 - 8.3e-07 28.7 0.0 1.6e-06 27.7 0.0 1.5 1 1 1 2 2 2 1 Flavodoxin-like fold Flavodoxin_1 PF00258.20 KLO16148.1 - 1e-06 28.7 0.0 1.9e-06 27.9 0.0 1.5 1 1 0 1 1 1 1 Flavodoxin Citrate_synt PF00285.16 KLO16149.1 - 3.1e-18 65.6 0.1 6.3e-15 54.7 0.0 3.7 2 1 1 3 3 3 2 Citrate synthase Ligase_CoA PF00549.14 KLO16149.1 - 1.2e-15 57.4 0.1 2.3e-15 56.5 0.1 1.5 1 0 0 1 1 1 1 CoA-ligase CoA_binding PF02629.14 KLO16149.1 - 8.5e-13 48.6 0.0 2.4e-12 47.1 0.0 1.9 1 0 0 1 1 1 1 CoA binding domain ATP-grasp_2 PF08442.5 KLO16149.1 - 3.9e-07 29.6 0.0 8.7e-07 28.5 0.0 1.6 1 0 0 1 1 1 1 ATP-grasp domain Succ_CoA_lig PF13607.1 KLO16149.1 - 1.8e-05 24.3 0.0 7.1e-05 22.4 0.0 1.9 2 0 0 2 2 2 1 Succinyl-CoA ligase like flavodoxin domain DUF2264 PF10022.4 KLO16150.1 - 1e-130 435.6 0.4 1.3e-130 435.2 0.3 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2264) DJ-1_PfpI PF01965.19 KLO16151.1 - 3e-27 94.8 0.1 4e-27 94.4 0.0 1.1 1 0 0 1 1 1 1 DJ-1/PfpI family DUF4066 PF13278.1 KLO16151.1 - 5.6e-15 55.0 0.0 6.4e-15 54.8 0.0 1.0 1 0 0 1 1 1 1 Putative amidotransferase GATase_3 PF07685.9 KLO16151.1 - 0.033 13.7 0.1 0.048 13.2 0.1 1.2 1 0 0 1 1 1 0 CobB/CobQ-like glutamine amidotransferase domain zf-MYND PF01753.13 KLO16152.1 - 1.8e-08 34.1 17.0 3.6e-08 33.1 11.8 1.6 1 0 0 1 1 1 1 MYND finger Adaptin_N PF01602.15 KLO16153.1 - 0.0019 16.6 0.1 0.0044 15.3 0.1 1.6 1 1 0 1 1 1 1 Adaptin N terminal region F-box-like PF12937.2 KLO16154.1 - 4e-08 32.8 0.0 1.1e-07 31.4 0.0 1.8 1 0 0 1 1 1 1 F-box-like F-box-like PF12937.2 KLO16156.1 - 5.7e-06 25.9 0.1 3.1e-05 23.5 0.0 2.4 2 0 0 2 2 2 1 F-box-like Ste50p-SAM PF09235.5 KLO16156.1 - 0.059 13.3 0.1 1.6 8.7 0.0 2.7 2 0 0 2 2 2 0 Ste50p, sterile alpha motif LRR_4 PF12799.2 KLO16156.1 - 1.6 8.4 8.2 10 5.8 0.0 4.6 3 1 0 3 3 3 0 Leucine Rich repeats (2 copies) F-box-like PF12937.2 KLO16157.1 - 1.7e-06 27.6 0.0 4.2e-06 26.3 0.0 1.7 1 0 0 1 1 1 1 F-box-like F-box-like PF12937.2 KLO16158.1 - 1.4e-08 34.3 0.3 4.2e-08 32.7 0.0 2.1 2 0 0 2 2 2 1 F-box-like DUF3491 PF11996.3 KLO16158.1 - 0.03 11.8 0.0 0.043 11.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3491) F-box-like PF12937.2 KLO16159.1 - 3.2e-08 33.1 0.0 7.9e-08 31.9 0.0 1.7 1 0 0 1 1 1 1 F-box-like CTNNBL PF08216.6 KLO16159.1 - 0.094 12.3 0.0 0.25 10.9 0.0 1.7 1 0 0 1 1 1 0 Catenin-beta-like, Arm-motif containing nuclear DUF3413 PF11893.3 KLO16161.1 - 0.23 10.3 4.1 0.39 9.5 2.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3413) F-box-like PF12937.2 KLO16163.1 - 1.9e-06 27.4 0.0 3.7e-06 26.5 0.0 1.5 1 0 0 1 1 1 1 F-box-like DUF2067 PF09840.4 KLO16163.1 - 0.076 12.5 0.0 0.13 11.7 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2067) Thoc2 PF11732.3 KLO16166.1 - 0.018 14.8 0.2 4.7 7.0 0.0 2.5 2 0 0 2 2 2 0 Transcription- and export-related complex subunit Thoc2 PF11732.3 KLO16168.1 - 0.14 11.9 1.0 5.9 6.7 0.1 2.5 2 0 0 2 2 2 0 Transcription- and export-related complex subunit UPF0546 PF10639.4 KLO16171.1 - 0.095 12.5 1.3 0.12 12.1 0.9 1.2 1 0 0 1 1 1 0 Uncharacterised protein family UPF0546 Saccharop_dh PF03435.13 KLO16174.1 - 2e-24 86.2 0.0 2.8e-24 85.8 0.0 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase NAD_binding_10 PF13460.1 KLO16174.1 - 8.3e-07 29.1 0.5 4e-06 26.9 0.4 2.0 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 KLO16174.1 - 1.5e-06 27.8 0.1 2.2e-06 27.2 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family DapB_N PF01113.15 KLO16174.1 - 0.00027 20.8 0.0 0.00071 19.4 0.0 1.8 1 1 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus Semialdhyde_dh PF01118.19 KLO16174.1 - 0.0015 18.8 0.0 0.0035 17.6 0.0 1.6 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain 3Beta_HSD PF01073.14 KLO16174.1 - 0.0043 15.7 0.0 0.0062 15.2 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Shikimate_DH PF01488.15 KLO16174.1 - 0.0074 16.3 0.0 0.014 15.5 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase adh_short PF00106.20 KLO16174.1 - 0.044 13.6 0.1 0.083 12.8 0.1 1.4 1 0 0 1 1 1 0 short chain dehydrogenase DUF2480 PF10652.4 KLO16174.1 - 0.071 12.6 0.1 0.15 11.6 0.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2480) NmrA PF05368.8 KLO16174.1 - 0.11 11.7 0.0 0.18 11.0 0.0 1.3 1 0 0 1 1 1 0 NmrA-like family F-box-like PF12937.2 KLO16175.1 - 5.9e-05 22.7 0.1 0.00013 21.5 0.1 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KLO16175.1 - 0.073 12.7 0.2 0.32 10.7 0.1 2.1 1 1 0 1 1 1 0 F-box domain F-box-like PF12937.2 KLO16176.1 - 6e-06 25.8 0.7 1.7e-05 24.4 0.5 1.9 1 0 0 1 1 1 1 F-box-like F-box-like PF12937.2 KLO16177.1 - 5.8e-06 25.9 0.1 1.3e-05 24.8 0.0 1.6 1 0 0 1 1 1 1 F-box-like F-box-like PF12937.2 KLO16180.1 - 3.3e-05 23.5 0.1 6.3e-05 22.6 0.0 1.5 1 0 0 1 1 1 1 F-box-like F-box-like PF12937.2 KLO16181.1 - 2.6e-05 23.8 0.3 7.1e-05 22.4 0.2 1.9 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KLO16181.1 - 0.052 13.2 0.0 0.17 11.5 0.0 1.9 1 0 0 1 1 1 0 F-box domain TMEM52 PF14979.1 KLO16181.1 - 0.1 12.4 0.6 0.48 10.3 0.1 2.0 2 0 0 2 2 2 0 Transmembrane 52 RNA_pol_Rpb4 PF03874.11 KLO16188.1 - 6.4e-22 77.7 2.4 9.3e-22 77.2 1.7 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb4 DED PF01335.16 KLO16188.1 - 0.019 15.0 0.4 0.082 13.0 0.0 2.0 2 0 0 2 2 2 0 Death effector domain Ank PF00023.25 KLO16189.1 - 4.8e-12 45.0 1.1 9.1e-05 22.0 0.1 3.3 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.1 KLO16189.1 - 1.6e-11 44.0 1.7 0.00047 20.3 0.1 3.5 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.2 KLO16189.1 - 2.7e-11 43.6 0.0 3.4e-05 24.0 0.0 2.2 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 KLO16189.1 - 1.2e-10 41.5 0.0 0.00052 20.4 0.0 2.4 2 1 0 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 KLO16189.1 - 3.5e-09 36.0 0.1 0.0044 17.1 0.0 3.6 4 0 0 4 4 4 2 Ankyrin repeat Peptidase_M49 PF03571.10 KLO16192.1 - 4.3e-185 615.9 0.0 5.2e-185 615.6 0.0 1.0 1 0 0 1 1 1 1 Peptidase family M49 Erp_C PF06780.6 KLO16192.1 - 0.051 13.4 0.2 0.12 12.2 0.1 1.6 1 0 0 1 1 1 0 Erp protein C-terminus Abhydrolase_4 PF08386.5 KLO16192.1 - 0.15 11.9 0.0 0.81 9.6 0.0 2.0 2 0 0 2 2 2 0 TAP-like protein Pkinase PF00069.20 KLO16193.1 - 1.4e-48 165.3 0.0 1.9e-48 164.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KLO16193.1 - 3.1e-44 151.0 0.0 4e-44 150.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KLO16193.1 - 3.3e-07 29.5 0.0 4.8e-07 29.0 0.0 1.1 1 0 0 1 1 1 1 Kinase-like Zn_clus PF00172.13 KLO16193.1 - 0.00087 19.1 8.0 0.00087 19.1 5.6 2.8 3 0 0 3 3 3 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Zn_clus PF00172.13 KLO16194.1 - 5.4e-07 29.4 13.4 8.6e-07 28.7 9.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pkinase PF00069.20 KLO16195.1 - 1.5e-38 132.4 0.0 2e-38 132.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KLO16195.1 - 4.7e-34 117.6 0.0 6.4e-34 117.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KLO16195.1 - 5.9e-05 22.1 0.0 9.1e-05 21.5 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 KLO16195.1 - 0.00023 21.0 0.0 0.00032 20.5 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family YrzO PF14142.1 KLO16195.1 - 0.099 12.3 0.1 0.19 11.3 0.1 1.4 1 0 0 1 1 1 0 YrzO-like protein Gti1_Pac2 PF09729.4 KLO16200.1 - 1.4e-26 93.3 0.9 1.7e-24 86.5 0.3 2.1 1 1 1 2 2 2 2 Gti1/Pac2 family Pkinase PF00069.20 KLO16202.1 - 1.3e-38 132.6 0.0 1.4e-38 132.5 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KLO16202.1 - 1.3e-34 119.4 0.0 1.5e-34 119.2 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KLO16202.1 - 0.00069 18.6 0.0 0.0011 18.0 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 KLO16202.1 - 0.0024 17.6 0.0 0.0049 16.6 0.0 1.5 1 1 1 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 KLO16202.1 - 0.085 12.4 0.0 3.1 7.3 0.0 2.1 1 1 1 2 2 2 0 Choline/ethanolamine kinase SOG2 PF10428.4 KLO16203.1 - 0.33 9.5 9.3 0.55 8.8 6.4 1.3 1 0 0 1 1 1 0 RAM signalling pathway protein Herpes_UL14 PF03580.9 KLO16204.1 - 0.016 15.0 0.1 0.025 14.3 0.1 1.2 1 0 0 1 1 1 0 Herpesvirus UL14-like protein Complex1_LYR PF05347.10 KLO16206.1 - 0.046 13.5 0.5 0.37 10.6 0.1 2.4 2 0 0 2 2 2 0 Complex 1 protein (LYR family) F-box-like PF12937.2 KLO16209.1 - 5.3e-05 22.8 0.3 0.00021 20.9 0.1 2.2 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 KLO16209.1 - 0.055 13.1 0.1 16 5.2 0.1 2.8 2 0 0 2 2 2 0 F-box domain Zn_clus PF00172.13 KLO16210.1 - 1.7e-06 27.7 7.3 4.4e-06 26.5 5.0 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain LacI PF00356.16 KLO16216.1 - 0.075 12.6 0.0 0.15 11.6 0.0 1.4 1 0 0 1 1 1 0 Bacterial regulatory proteins, lacI family Zn_clus PF00172.13 KLO16219.1 - 1.9e-06 27.6 7.1 4.1e-06 26.5 4.9 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RseC_MucC PF04246.7 KLO16221.1 - 0.37 10.3 7.6 0.44 10.1 1.6 2.3 2 0 0 2 2 2 0 Positive regulator of sigma(E), RseC/MucC DUF1077 PF06417.7 KLO16221.1 - 0.6 9.4 3.1 1.1 8.6 2.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1077) Zn_clus PF00172.13 KLO16222.1 - 1.3e-08 34.6 13.4 1.9e-08 34.0 9.3 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Zn_clus PF00172.13 KLO16226.1 - 0.0036 17.1 16.3 0.0036 17.1 11.3 1.6 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Zn_clus PF00172.13 KLO16227.1 - 0.0019 18.0 16.6 0.0019 18.0 11.5 1.8 1 1 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Eclosion PF04736.7 KLO16227.1 - 1 8.8 6.2 2.4 7.6 4.3 1.5 1 0 0 1 1 1 0 Eclosion hormone Zn_clus PF00172.13 KLO16228.1 - 6.7e-05 22.7 5.1 9.9e-05 22.1 3.5 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Zn_clus PF00172.13 KLO16229.1 - 2.9e-05 23.8 5.7 3.9e-05 23.4 3.9 1.1 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Dickkopf_N PF04706.7 KLO16229.1 - 0.36 11.0 6.5 1.7 8.8 4.5 1.9 1 1 0 1 1 1 0 Dickkopf N-terminal cysteine-rich region Zn_clus PF00172.13 KLO16230.1 - 4.7e-06 26.4 14.1 7.2e-06 25.8 9.8 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain FAD_binding_4 PF01565.18 KLO16231.1 - 5.1e-13 48.6 0.0 2.2e-07 30.4 0.0 2.9 2 1 0 2 2 2 2 FAD binding domain BBE PF08031.7 KLO16231.1 - 5.8e-07 29.3 0.0 1.1e-06 28.3 0.0 1.4 1 0 0 1 1 1 1 Berberine and berberine like Cytokin-bind PF09265.5 KLO16231.1 - 0.013 14.6 0.0 0.021 13.9 0.0 1.2 1 0 0 1 1 1 0 Cytokinin dehydrogenase 1, FAD and cytokinin binding XET_C PF06955.7 KLO16235.1 - 1.4 8.6 4.7 0.56 9.9 0.5 2.1 2 0 0 2 2 2 0 Xyloglucan endo-transglycosylase (XET) C-terminus Glyco_hydro_31 PF01055.21 KLO16236.1 - 2.1e-159 531.0 1.6 2.7e-159 530.7 1.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.1 KLO16236.1 - 2.1e-05 24.2 0.0 8.4e-05 22.3 0.0 2.1 1 0 0 1 1 1 1 Galactose mutarotase-like Ribosomal_L33 PF00471.15 KLO16237.1 - 1.7e-10 40.9 0.0 2.1e-10 40.7 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L33 Nudix_N PF12535.3 KLO16237.1 - 0.057 12.8 0.0 0.08 12.4 0.0 1.3 1 0 0 1 1 1 0 Hydrolase of X-linked nucleoside diphosphate N terminal SURF1 PF02104.10 KLO16238.1 - 0.041 13.7 0.0 0.061 13.1 0.0 1.3 1 0 0 1 1 1 0 SURF1 family HMG_box PF00505.14 KLO16240.1 - 8.5e-17 61.1 2.1 1.5e-16 60.4 1.5 1.4 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 KLO16240.1 - 9.7e-13 48.2 0.9 9.7e-13 48.2 0.6 1.7 2 0 0 2 2 2 1 HMG-box domain adh_short_C2 PF13561.1 KLO16241.1 - 9.2e-34 117.2 0.4 1.1e-33 117.0 0.3 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 KLO16241.1 - 2.7e-22 79.4 2.1 3.7e-22 78.9 1.5 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KLO16241.1 - 1.1e-11 44.7 0.3 1.5e-11 44.3 0.2 1.1 1 0 0 1 1 1 1 KR domain Saccharop_dh PF03435.13 KLO16241.1 - 0.0003 19.9 0.1 0.0005 19.1 0.0 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase Adenine_deam_C PF13382.1 KLO16241.1 - 0.011 14.8 0.1 0.02 14.0 0.1 1.3 1 0 0 1 1 1 0 Adenine deaminase C-terminal domain DUF3255 PF11631.3 KLO16241.1 - 0.023 14.2 0.1 3.8 7.1 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3255) His_biosynth PF00977.16 KLO16241.1 - 0.039 13.2 0.1 0.076 12.2 0.0 1.4 1 0 0 1 1 1 0 Histidine biosynthesis protein DUF2527 PF10736.4 KLO16243.1 - 0.033 13.7 0.0 0.074 12.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2627) Mem_trans PF03547.13 KLO16244.1 - 2.8e-35 121.3 1.4 3.4e-35 121.0 1.0 1.0 1 0 0 1 1 1 1 Membrane transport protein Ribosomal_L33 PF00471.15 KLO16245.1 - 1.7e-10 40.9 0.0 2.1e-10 40.7 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L33 Nudix_N PF12535.3 KLO16245.1 - 0.056 12.8 0.0 0.08 12.4 0.0 1.3 1 0 0 1 1 1 0 Hydrolase of X-linked nucleoside diphosphate N terminal Glyco_hydro_31 PF01055.21 KLO16247.1 - 1.4e-161 538.2 1.2 1.8e-161 537.8 0.8 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.1 KLO16247.1 - 5.4e-06 26.1 0.1 1.6e-05 24.6 0.0 1.9 1 0 0 1 1 1 1 Galactose mutarotase-like LRR_4 PF12799.2 KLO16250.1 - 0.00015 21.3 0.9 0.018 14.6 0.2 3.7 2 2 1 3 3 3 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KLO16250.1 - 0.0039 16.9 0.2 0.043 13.5 0.1 2.7 1 1 0 1 1 1 1 Leucine rich repeat LRR_4 PF12799.2 KLO16253.1 - 0.89 9.2 6.2 8.7 6.0 0.2 3.7 4 1 0 4 4 4 0 Leucine Rich repeats (2 copies) Pyridoxal_deC PF00282.14 KLO16255.1 - 6e-18 64.4 0.0 8.6e-10 37.5 0.0 3.1 2 1 0 2 2 2 2 Pyridoxal-dependent decarboxylase conserved domain PTCB-BRCT PF12738.2 KLO16256.1 - 2.7e-29 100.8 0.6 1.6e-17 63.0 0.0 4.6 4 0 0 4 4 4 4 twin BRCT domain BRCT PF00533.21 KLO16256.1 - 1.6e-25 89.0 1.3 1.2e-08 34.9 0.0 6.3 6 0 0 6 6 6 4 BRCA1 C Terminus (BRCT) domain Phage_Mu_Gam PF07352.7 KLO16257.1 - 0.032 13.7 2.1 0.049 13.1 1.5 1.2 1 0 0 1 1 1 0 Bacteriophage Mu Gam like protein Lactamase_B_2 PF12706.2 KLO16259.1 - 3.6e-22 78.8 0.0 4.7e-22 78.4 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 KLO16259.1 - 5e-07 29.5 0.0 1.4e-06 28.1 0.0 1.7 2 0 0 2 2 2 1 Metallo-beta-lactamase superfamily PDEase_II PF02112.10 KLO16259.1 - 0.00023 20.1 0.0 0.0005 19.1 0.0 1.4 2 0 0 2 2 2 1 cAMP phosphodiesterases class-II ECH PF00378.15 KLO16260.1 - 1.1e-41 142.6 0.7 1.3e-41 142.3 0.5 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family Gag_p30 PF02093.11 KLO16261.1 - 0.04 13.1 0.0 0.08 12.1 0.0 1.4 1 0 0 1 1 1 0 Gag P30 core shell protein ERM PF00769.14 KLO16263.1 - 0.0017 17.9 11.7 0.0017 17.9 8.1 1.9 2 0 0 2 2 2 1 Ezrin/radixin/moesin family Mod_r PF07200.8 KLO16263.1 - 0.035 14.0 3.4 0.067 13.1 2.3 1.4 1 0 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein THOC7 PF05615.8 KLO16263.1 - 0.036 14.3 4.1 0.074 13.3 2.9 1.5 1 0 0 1 1 1 0 Tho complex subunit 7 DUF4337 PF14235.1 KLO16263.1 - 2.9 7.7 14.3 0.15 11.9 6.1 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4337) DEAD PF00270.24 KLO16265.1 - 1e-20 73.8 0.0 8e-14 51.4 0.0 2.4 1 1 0 2 2 2 2 DEAD/DEAH box helicase Helicase_C PF00271.26 KLO16265.1 - 2.5e-10 40.0 0.0 5.3e-10 39.0 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 KLO16265.1 - 2.5e-05 24.1 0.0 0.0001 22.2 0.0 2.1 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit SNF2_N PF00176.18 KLO16265.1 - 0.00012 20.9 0.0 0.00019 20.3 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain LSM PF01423.17 KLO16266.1 - 9.7e-17 60.2 0.3 1.1e-16 60.1 0.2 1.0 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 KLO16266.1 - 4.7e-06 26.4 0.2 6.2e-06 26.0 0.1 1.2 1 0 0 1 1 1 1 Ataxin 2 SM domain GMC_oxred_N PF00732.14 KLO16270.1 - 7e-51 173.1 0.0 9.8e-51 172.6 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 KLO16270.1 - 1.2e-32 113.1 0.0 2.4e-32 112.1 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 KLO16270.1 - 5.2e-07 28.9 1.5 0.00023 20.2 0.2 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 KLO16270.1 - 7e-07 28.4 1.5 0.00033 19.6 0.4 2.2 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.1 KLO16270.1 - 1.7e-05 24.7 0.2 5.4e-05 23.1 0.1 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 KLO16270.1 - 9.6e-05 21.4 0.3 0.00015 20.8 0.2 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_3 PF13738.1 KLO16270.1 - 0.0001 22.4 0.2 0.038 14.0 0.1 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 KLO16270.1 - 0.00077 19.4 0.1 0.0055 16.5 0.1 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 KLO16270.1 - 0.032 13.9 0.1 0.096 12.4 0.1 1.8 2 0 0 2 2 2 0 FAD-NAD(P)-binding HI0933_like PF03486.9 KLO16270.1 - 0.054 11.9 0.7 0.091 11.2 0.1 1.6 2 0 0 2 2 2 0 HI0933-like protein Thi4 PF01946.12 KLO16270.1 - 0.078 12.0 0.3 0.13 11.3 0.2 1.3 1 0 0 1 1 1 0 Thi4 family GIDA PF01134.17 KLO16270.1 - 0.08 11.7 0.1 0.17 10.7 0.0 1.5 2 0 0 2 2 2 0 Glucose inhibited division protein A DUF4021 PF13213.1 KLO16270.1 - 0.32 10.6 1.5 1.1 8.9 0.8 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF4021) GMC_oxred_N PF00732.14 KLO16271.1 - 4.4e-55 186.9 0.1 6e-55 186.4 0.1 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 KLO16271.1 - 2.2e-31 109.0 0.1 3.7e-31 108.3 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.19 KLO16271.1 - 3.3e-07 29.5 0.9 0.00063 18.6 0.3 2.4 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.19 KLO16271.1 - 7.4e-07 28.3 0.3 1.7e-06 27.1 0.0 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KLO16271.1 - 2.5e-05 24.1 0.3 8.1e-05 22.5 0.2 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 KLO16271.1 - 4.5e-05 23.6 0.1 0.012 15.6 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 KLO16271.1 - 0.00031 19.7 0.1 0.00052 19.0 0.0 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_2 PF07992.9 KLO16271.1 - 0.00072 19.4 0.0 0.0028 17.5 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 KLO16271.1 - 0.022 13.6 0.1 0.037 12.8 0.0 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A NAD_binding_9 PF13454.1 KLO16271.1 - 0.041 13.6 0.0 0.083 12.6 0.0 1.5 1 0 0 1 1 1 0 FAD-NAD(P)-binding Thi4 PF01946.12 KLO16271.1 - 0.072 12.1 0.3 0.13 11.3 0.2 1.3 1 0 0 1 1 1 0 Thi4 family HI0933_like PF03486.9 KLO16271.1 - 0.091 11.2 0.2 0.17 10.2 0.2 1.4 1 0 0 1 1 1 0 HI0933-like protein Dynamin_N PF00350.18 KLO16273.1 - 1.8e-12 47.3 0.0 8.7e-12 45.1 0.0 2.2 1 1 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.18 KLO16273.1 - 4.2e-06 26.7 0.0 0.017 15.0 0.0 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase FtsK_SpoIIIE PF01580.13 KLO16273.1 - 0.017 14.6 0.8 0.86 9.0 0.0 2.9 3 0 0 3 3 3 0 FtsK/SpoIIIE family FeoB_N PF02421.13 KLO16273.1 - 0.061 12.5 0.0 5.2 6.3 0.0 2.4 2 0 0 2 2 2 0 Ferrous iron transport protein B DUF479 PF04336.7 KLO16273.1 - 1.5 8.9 6.0 24 5.0 0.1 4.1 4 1 0 4 4 4 0 Protein of unknown function, DUF479 Dynamin_N PF00350.18 KLO16274.1 - 2.5e-10 40.4 0.0 1.3e-09 38.0 0.0 2.2 2 0 0 2 2 2 1 Dynamin family MMR_HSR1 PF01926.18 KLO16274.1 - 0.0028 17.5 0.0 2.2 8.2 0.0 2.9 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_10 PF12846.2 KLO16274.1 - 0.72 9.2 3.7 3.1 7.1 0.2 2.9 3 0 0 3 3 3 0 AAA-like domain Dynamin_N PF00350.18 KLO16275.1 - 0.0057 16.4 0.0 0.011 15.5 0.0 1.4 1 0 0 1 1 1 1 Dynamin family Dynamin_N PF00350.18 KLO16276.1 - 1.9e-06 27.8 0.0 7.9e-05 22.5 0.0 3.1 2 1 0 2 2 2 1 Dynamin family GMC_oxred_N PF00732.14 KLO16277.1 - 6.1e-51 173.3 0.0 8.6e-51 172.8 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 KLO16277.1 - 1.1e-30 106.8 0.0 1.9e-30 106.0 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 KLO16277.1 - 2.8e-06 26.4 0.1 0.00047 19.1 0.1 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 KLO16277.1 - 1.5e-05 24.0 0.1 0.0083 15.0 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.1 KLO16277.1 - 0.00013 21.8 0.1 0.00041 20.3 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 KLO16277.1 - 0.00062 18.7 0.0 0.00093 18.2 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_3 PF13738.1 KLO16277.1 - 0.0022 18.0 0.0 0.4 10.6 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.13 KLO16277.1 - 0.12 12.3 0.1 0.25 11.3 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain dCMP_cyt_deam_1 PF00383.17 KLO16279.1 - 6.2e-18 64.3 0.1 9.8e-18 63.6 0.1 1.3 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region APOBEC_N PF08210.6 KLO16279.1 - 0.0012 18.5 0.1 0.002 17.8 0.1 1.5 1 1 0 1 1 1 1 APOBEC-like N-terminal domain MafB19-deam PF14437.1 KLO16279.1 - 0.0091 15.6 0.0 0.014 14.9 0.0 1.3 1 0 0 1 1 1 1 MafB19-like deaminase XOO_2897-deam PF14440.1 KLO16279.1 - 0.017 14.8 0.1 0.034 13.8 0.0 1.5 2 0 0 2 2 2 0 Xanthomonas XOO_2897-like deaminase Bd3614-deam PF14439.1 KLO16279.1 - 0.073 12.9 0.9 0.22 11.4 0.6 1.7 1 1 0 1 1 1 0 Bd3614-like deaminase DUF1843 PF08898.5 KLO16279.1 - 0.12 12.4 0.3 1.4 9.0 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF1843) Toxin-deaminase PF14424.1 KLO16279.1 - 0.16 11.9 1.1 1.3 9.0 0.1 2.3 2 1 0 2 2 2 0 The BURPS668_1122 family of deaminases NAP PF00956.13 KLO16280.1 - 2.7e-79 265.7 4.0 2.7e-79 265.7 2.8 2.0 2 0 0 2 2 2 1 Nucleosome assembly protein (NAP) He_PIG PF05345.7 KLO16281.1 - 2.5e-07 30.6 14.8 6.3e-05 22.9 1.2 4.2 4 0 0 4 4 4 2 Putative Ig domain Aldedh PF00171.17 KLO16282.1 - 7.7e-188 624.5 0.1 8.7e-188 624.3 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 KLO16282.1 - 2.5e-05 23.1 0.0 4e-05 22.5 0.0 1.2 1 0 0 1 1 1 1 Acyl-CoA reductase (LuxC) DUF1487 PF07368.6 KLO16282.1 - 0.00083 18.6 0.0 0.42 9.8 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF1487) zf-H2C2_2 PF13465.1 KLO16283.1 - 0.084 13.2 0.9 14 6.2 0.0 2.6 2 0 0 2 2 2 0 Zinc-finger double domain WHG PF13305.1 KLO16283.1 - 0.11 13.1 0.0 0.32 11.6 0.0 1.8 1 0 0 1 1 1 0 WHG domain DUF1610 PF07754.6 KLO16283.1 - 8 6.6 6.5 4.1 7.6 1.6 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1610) Dynamin_N PF00350.18 KLO16285.1 - 4.3e-11 42.9 0.7 6.3e-10 39.1 0.0 2.9 3 0 0 3 3 3 1 Dynamin family MMR_HSR1 PF01926.18 KLO16285.1 - 0.0002 21.2 0.0 0.85 9.5 0.0 3.0 3 0 0 3 3 3 2 50S ribosome-binding GTPase DUF3463 PF11946.3 KLO16285.1 - 0.056 13.0 0.0 0.15 11.6 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3463) HAMP PF00672.20 KLO16286.1 - 0.2 11.8 0.9 0.6 10.3 0.0 2.2 2 0 0 2 2 2 0 HAMP domain DNA_primase_S PF01896.14 KLO16287.1 - 0.016 15.0 0.0 0.02 14.6 0.0 1.3 1 0 0 1 1 1 0 Eukaryotic and archaeal DNA primase small subunit Oxysterol_BP PF01237.13 KLO16288.1 - 1.2e-115 385.8 0.0 1.7e-115 385.3 0.0 1.2 1 0 0 1 1 1 1 Oxysterol-binding protein Ank_2 PF12796.2 KLO16288.1 - 2.1e-13 50.3 0.1 1.1e-10 41.7 0.0 2.4 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.1 KLO16288.1 - 3.4e-13 49.3 0.2 2.5e-09 37.0 0.1 3.7 3 1 1 4 4 4 1 Ankyrin repeats (many copies) Ank PF00023.25 KLO16288.1 - 4.6e-12 45.1 0.8 0.00048 19.8 0.0 3.6 3 0 0 3 3 3 3 Ankyrin repeat Ank_4 PF13637.1 KLO16288.1 - 4e-11 43.1 1.1 4.6e-08 33.3 0.0 2.8 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 KLO16288.1 - 1.6e-09 37.0 0.5 0.01 15.9 0.0 4.2 4 0 0 4 4 4 2 Ankyrin repeat PH PF00169.24 KLO16288.1 - 2e-08 34.3 0.0 4.2e-08 33.3 0.0 1.6 1 0 0 1 1 1 1 PH domain PH_11 PF15413.1 KLO16288.1 - 6e-07 29.7 0.0 1.4e-06 28.5 0.0 1.7 1 0 0 1 1 1 1 Pleckstrin homology domain PH_8 PF15409.1 KLO16288.1 - 0.0011 18.9 2.4 0.0053 16.8 0.4 2.7 2 1 0 2 2 2 1 Pleckstrin homology domain iPGM_N PF06415.8 KLO16289.1 - 6.4e-75 251.3 0.0 9.1e-75 250.8 0.0 1.2 1 0 0 1 1 1 1 BPG-independent PGAM N-terminus (iPGM_N) Metalloenzyme PF01676.13 KLO16289.1 - 4.9e-71 239.0 0.6 5.6e-71 238.8 0.4 1.0 1 0 0 1 1 1 1 Metalloenzyme superfamily Sulfatase PF00884.18 KLO16289.1 - 7.7e-09 35.1 0.0 1.5e-07 30.9 0.0 2.5 2 1 0 2 2 2 1 Sulfatase Phosphodiest PF01663.17 KLO16289.1 - 3.4e-07 29.9 0.3 6.1e-07 29.0 0.0 1.5 2 0 0 2 2 2 1 Type I phosphodiesterase / nucleotide pyrophosphatase PglZ PF08665.7 KLO16289.1 - 0.0075 15.9 0.0 0.023 14.3 0.0 1.8 2 0 0 2 2 2 1 PglZ domain Exostosin PF03016.10 KLO16289.1 - 0.1 11.6 0.0 0.18 10.8 0.0 1.3 1 0 0 1 1 1 0 Exostosin family FG-GAP PF01839.18 KLO16290.1 - 3.1e-05 23.5 0.2 0.13 11.9 0.0 3.1 2 0 0 2 2 2 2 FG-GAP repeat VCBS PF13517.1 KLO16290.1 - 0.00064 20.0 4.8 5.9 7.3 0.0 5.2 5 1 1 6 6 6 3 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella RicinB_lectin_2 PF14200.1 KLO16290.1 - 0.00098 19.4 0.1 0.027 14.8 0.0 2.8 2 1 1 3 3 3 2 Ricin-type beta-trefoil lectin domain-like WW PF00397.21 KLO16291.1 - 0.0051 16.6 2.6 0.011 15.5 1.8 1.6 1 0 0 1 1 1 1 WW domain TPM PF04536.9 KLO16293.1 - 0.044 13.6 0.1 0.14 11.9 0.1 1.9 1 1 0 1 1 1 0 TLP18.3, Psb32 and MOLO-1 founding proteins of phosphatase Dynamin_N PF00350.18 KLO16294.1 - 8.4e-12 45.2 0.0 1.6e-09 37.7 0.0 3.8 3 1 0 3 3 3 1 Dynamin family MMR_HSR1 PF01926.18 KLO16294.1 - 0.0003 20.7 0.0 0.049 13.5 0.0 3.1 2 0 0 2 2 2 2 50S ribosome-binding GTPase MoeA_N PF03453.12 KLO16304.1 - 5.7e-35 120.0 0.1 8.2e-35 119.5 0.0 1.3 1 0 0 1 1 1 1 MoeA N-terminal region (domain I and II) MoCF_biosynth PF00994.19 KLO16304.1 - 8.1e-29 99.8 0.0 1.3e-28 99.1 0.0 1.4 1 0 0 1 1 1 1 Probable molybdopterin binding domain MoeA_C PF03454.10 KLO16304.1 - 2.8e-13 49.6 0.0 5.9e-13 48.5 0.0 1.6 1 0 0 1 1 1 1 MoeA C-terminal region (domain IV) PI3_PI4_kinase PF00454.22 KLO16306.1 - 1.1e-50 172.2 0.0 2.9e-50 170.9 0.0 1.7 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FAT PF02259.18 KLO16306.1 - 1.2e-27 96.8 2.7 2.9e-27 95.6 1.9 1.6 1 0 0 1 1 1 1 FAT domain UME PF08064.8 KLO16306.1 - 2.5e-21 75.6 0.0 9e-21 73.8 0.0 2.1 1 0 0 1 1 1 1 UME (NUC010) domain FATC PF02260.15 KLO16306.1 - 1e-12 47.2 0.2 6.6e-12 44.6 0.0 2.3 2 0 0 2 2 2 1 FATC domain YEATS PF03366.11 KLO16307.1 - 1.6e-33 114.2 0.1 2.6e-33 113.5 0.1 1.4 1 0 0 1 1 1 1 YEATS family Coiled-coil_56 PF09813.4 KLO16308.1 - 5.3e-07 29.5 0.1 1.2e-06 28.3 0.0 1.7 1 1 0 1 1 1 1 Coiled-coil domain-containing protein 56 COX7a PF02238.10 KLO16308.1 - 0.00079 19.1 0.0 0.0015 18.2 0.0 1.4 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIIa DUF3422 PF11902.3 KLO16308.1 - 0.082 11.7 0.1 0.14 11.0 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3422) Ribonucleas_3_3 PF14622.1 KLO16309.1 - 2.6e-17 62.9 0.0 3.8e-17 62.4 0.0 1.2 1 0 0 1 1 1 1 Ribonuclease-III-like Ribonuclease_3 PF00636.21 KLO16309.1 - 5.2e-16 59.1 0.0 9.8e-16 58.2 0.0 1.5 1 0 0 1 1 1 1 Ribonuclease III domain dsrm PF00035.20 KLO16309.1 - 1.3e-09 38.4 0.1 4.2e-09 36.8 0.0 1.9 2 0 0 2 2 2 1 Double-stranded RNA binding motif PAPS_reduct PF01507.14 KLO16310.1 - 1e-38 132.8 0.0 1.4e-38 132.4 0.0 1.2 1 0 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family CDC37_C PF08564.5 KLO16310.1 - 0.072 12.9 0.0 0.17 11.7 0.0 1.6 1 0 0 1 1 1 0 Cdc37 C terminal domain IncA PF04156.9 KLO16311.1 - 0.12 11.9 2.3 0.21 11.1 1.6 1.3 1 0 0 1 1 1 0 IncA protein GET2 PF08690.5 KLO16311.1 - 0.13 11.4 6.3 0.21 10.7 4.4 1.2 1 0 0 1 1 1 0 GET complex subunit GET2 Asp_protease PF09668.5 KLO16312.1 - 1.8e-20 72.7 0.2 3.2e-20 71.9 0.1 1.4 1 0 0 1 1 1 1 Aspartyl protease ubiquitin PF00240.18 KLO16312.1 - 4.4e-07 29.2 0.0 7.8e-07 28.4 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family gag-asp_proteas PF13975.1 KLO16312.1 - 0.0005 19.8 0.0 0.0012 18.6 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.1 KLO16312.1 - 0.008 16.6 0.0 0.03 14.8 0.0 1.9 2 0 0 2 2 2 1 Aspartyl protease Rad60-SLD PF11976.3 KLO16312.1 - 0.008 15.8 0.0 0.017 14.8 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like XPC-binding PF09280.6 KLO16312.1 - 0.09 12.2 0.8 0.33 10.4 0.0 2.2 2 0 0 2 2 2 0 XPC-binding domain Ubiquitin_2 PF14560.1 KLO16312.1 - 0.093 12.9 0.1 0.33 11.2 0.0 2.0 2 1 0 2 2 2 0 Ubiquitin-like domain YukD PF08817.5 KLO16312.1 - 0.11 13.0 0.5 1 9.9 0.0 2.7 3 1 0 3 3 3 0 WXG100 protein secretion system (Wss), protein YukD TFIID-18kDa PF02269.11 KLO16313.1 - 2.1e-32 110.7 0.1 4.3e-32 109.7 0.0 1.5 1 0 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit Sec5 PF15469.1 KLO16313.1 - 0.037 13.7 0.1 0.064 12.9 0.0 1.3 1 0 0 1 1 1 0 Exocyst complex component Sec5 CytochromB561_N PF09786.4 KLO16314.1 - 7.3 4.9 9.9 0.19 10.1 0.5 2.0 2 0 0 2 2 2 0 Cytochrome B561, N terminal BTB PF00651.26 KLO16316.1 - 1.5e-05 24.8 0.2 3.2e-05 23.8 0.1 1.5 1 0 0 1 1 1 1 BTB/POZ domain UPF0029 PF01205.14 KLO16317.1 - 7.1e-28 96.4 0.0 1.4e-27 95.5 0.0 1.5 1 0 0 1 1 1 1 Uncharacterized protein family UPF0029 RWD PF05773.17 KLO16317.1 - 1e-06 28.6 0.0 2.1e-06 27.6 0.0 1.6 1 1 0 1 1 1 1 RWD domain p450 PF00067.17 KLO16318.1 - 5.2e-16 58.2 0.0 6.6e-16 57.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 KLO16319.1 - 1.5e-46 158.9 0.1 9.9e-46 156.1 0.1 1.9 1 1 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 KLO16320.1 - 5.9e-67 226.1 0.2 5.8e-66 222.9 0.1 2.1 1 1 0 1 1 1 1 Cytochrome P450 COX2_TM PF02790.10 KLO16322.1 - 0.22 11.5 3.9 0.17 11.8 0.8 2.0 2 0 0 2 2 2 0 Cytochrome C oxidase subunit II, transmembrane domain Dynamin_N PF00350.18 KLO16323.1 - 2.4e-15 56.7 7.9 2.5e-15 56.6 0.0 3.7 3 1 0 3 3 3 1 Dynamin family MMR_HSR1 PF01926.18 KLO16323.1 - 0.00011 22.1 0.1 0.014 15.3 0.1 2.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase DUF258 PF03193.11 KLO16323.1 - 0.0042 16.2 0.1 0.023 13.9 0.1 2.2 2 0 0 2 2 2 1 Protein of unknown function, DUF258 FtsK_SpoIIIE PF01580.13 KLO16323.1 - 0.018 14.5 0.4 0.11 11.9 0.0 2.4 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_16 PF13191.1 KLO16323.1 - 0.032 14.2 0.3 0.41 10.6 0.0 2.8 3 0 0 3 3 3 0 AAA ATPase domain AAA_22 PF13401.1 KLO16323.1 - 0.042 13.9 0.1 0.22 11.6 0.0 2.3 2 1 0 2 2 2 0 AAA domain ABC_tran PF00005.22 KLO16323.1 - 0.27 11.5 0.1 0.27 11.5 0.0 3.0 3 0 0 3 3 3 0 ABC transporter Thiolase_N PF00108.18 KLO16325.1 - 2.4e-89 298.8 1.9 3.2e-89 298.3 1.3 1.1 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 KLO16325.1 - 4.2e-42 142.4 1.0 1.1e-41 141.1 0.5 1.8 2 0 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.21 KLO16325.1 - 0.001 18.5 3.1 0.038 13.4 1.5 2.4 1 1 1 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III_C PF08541.5 KLO16325.1 - 0.0041 17.0 0.1 0.018 15.0 0.1 2.1 1 0 0 1 1 1 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal ACP_syn_III PF08545.5 KLO16325.1 - 0.14 11.8 1.3 5.1 6.8 0.1 2.9 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III MFS_1 PF07690.11 KLO16326.1 - 1.2e-36 126.2 22.7 1.5e-36 125.8 15.8 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily OSTbeta PF15048.1 KLO16326.1 - 0.17 11.9 0.0 0.39 10.7 0.0 1.6 1 0 0 1 1 1 0 Organic solute transporter subunit beta protein MFS_1 PF07690.11 KLO16327.1 - 1.3e-33 116.2 28.8 1.7e-33 115.7 20.0 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily PrgI PF12666.2 KLO16327.1 - 0.086 12.9 0.4 0.086 12.9 0.2 4.1 4 1 0 4 4 4 0 PrgI family protein Autophagy_act_C PF03987.10 KLO16328.1 - 6.4e-11 42.2 1.1 3.3e-10 39.9 0.7 2.1 1 1 0 1 1 1 1 Autophagocytosis associated protein, active-site domain Ribosomal_S3Ae PF01015.13 KLO16329.1 - 9.5e-83 276.3 4.3 1.1e-82 276.0 3.0 1.0 1 0 0 1 1 1 1 Ribosomal S3Ae family Ph1570 PF09638.5 KLO16329.1 - 0.061 13.1 0.3 8.3 6.1 0.1 2.4 2 0 0 2 2 2 0 Ph1570 protein Abhydro_lipase PF04083.11 KLO16329.1 - 0.067 12.5 0.0 0.12 11.6 0.0 1.4 1 0 0 1 1 1 0 Partial alpha/beta-hydrolase lipase region Pribosyltran PF00156.22 KLO16330.1 - 2.8e-16 59.3 0.1 3.7e-16 58.9 0.0 1.2 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.1 KLO16330.1 - 0.0036 16.5 0.0 0.006 15.8 0.0 1.3 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Glyco_hydro_47 PF01532.15 KLO16331.1 - 3.9e-121 404.8 0.0 4.9e-121 404.5 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 PA PF02225.17 KLO16331.1 - 2e-09 37.0 0.0 3.9e-09 36.0 0.0 1.5 1 0 0 1 1 1 1 PA domain Auto_anti-p27 PF06677.7 KLO16332.1 - 5.3e-13 48.4 1.6 1.7e-06 27.6 0.1 2.8 3 0 0 3 3 3 2 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) Tub_2 PF04525.7 KLO16334.1 - 0.015 14.6 0.0 0.024 14.0 0.0 1.3 1 0 0 1 1 1 0 Tubby C 2 ACPS PF01648.15 KLO16336.1 - 4.7e-22 77.9 0.0 5.4e-22 77.7 0.0 1.0 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily GCV_T PF01571.16 KLO16337.1 - 6e-15 55.1 0.0 1e-13 51.1 0.0 2.2 1 1 0 1 1 1 1 Aminomethyltransferase folate-binding domain GCV_T_C PF08669.6 KLO16337.1 - 0.043 13.8 0.0 0.24 11.4 0.0 2.2 3 0 0 3 3 3 0 Glycine cleavage T-protein C-terminal barrel domain Pet191_N PF10203.4 KLO16338.1 - 2.7e-26 91.3 3.6 2.9e-26 91.2 2.5 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein PET191 Cmc1 PF08583.5 KLO16338.1 - 0.063 13.0 5.0 0.87 9.4 0.3 2.2 2 0 0 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like RNA_pol_L_2 PF13656.1 KLO16338.1 - 0.13 11.6 0.0 3.2 7.2 0.0 2.1 1 1 1 2 2 2 0 RNA polymerase Rpb3/Rpb11 dimerisation domain CHCH PF06747.8 KLO16338.1 - 2.8 7.9 5.3 6.5 6.8 0.1 2.6 3 0 0 3 3 3 0 CHCH domain ATP_bind_1 PF03029.12 KLO16339.1 - 1.7e-75 253.6 0.0 2e-75 253.3 0.0 1.1 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein AAA_17 PF13207.1 KLO16339.1 - 0.00011 22.9 0.1 0.00015 22.5 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 KLO16339.1 - 0.00021 21.3 0.0 0.00041 20.3 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 KLO16339.1 - 0.00024 21.2 0.0 0.00042 20.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain MobB PF03205.9 KLO16339.1 - 0.0011 18.7 0.0 0.0069 16.0 0.0 2.0 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B KaiC PF06745.8 KLO16339.1 - 0.0019 17.3 0.0 0.0028 16.7 0.0 1.3 1 0 0 1 1 1 1 KaiC AAA_10 PF12846.2 KLO16339.1 - 0.0024 17.3 0.0 0.0041 16.6 0.0 1.4 1 0 0 1 1 1 1 AAA-like domain AAA_18 PF13238.1 KLO16339.1 - 0.0046 17.2 0.0 0.01 16.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.1 KLO16339.1 - 0.0056 16.1 0.0 0.011 15.2 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain T2SE PF00437.15 KLO16339.1 - 0.0061 15.5 0.0 0.0087 14.9 0.0 1.2 1 0 0 1 1 1 1 Type II/IV secretion system protein NACHT PF05729.7 KLO16339.1 - 0.0063 16.1 0.0 0.012 15.2 0.0 1.5 1 0 0 1 1 1 1 NACHT domain AAA_33 PF13671.1 KLO16339.1 - 0.0076 16.1 0.0 0.013 15.4 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.1 KLO16339.1 - 0.008 16.0 0.0 0.016 15.1 0.0 1.6 1 1 0 1 1 1 1 AAA domain RNA_helicase PF00910.17 KLO16339.1 - 0.012 15.7 0.0 0.045 13.9 0.0 1.9 2 0 0 2 2 2 0 RNA helicase CbiA PF01656.18 KLO16339.1 - 0.013 14.9 0.0 0.033 13.5 0.0 1.6 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_24 PF13479.1 KLO16339.1 - 0.015 14.8 0.0 0.028 14.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.10 KLO16339.1 - 0.025 14.2 0.0 0.047 13.3 0.0 1.4 1 0 0 1 1 1 0 NTPase ArgK PF03308.11 KLO16339.1 - 0.042 12.6 0.0 0.065 11.9 0.0 1.2 1 0 0 1 1 1 0 ArgK protein DUF87 PF01935.12 KLO16339.1 - 0.042 13.6 0.0 0.12 12.1 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function DUF87 MMR_HSR1 PF01926.18 KLO16339.1 - 0.045 13.7 0.0 0.078 12.9 0.0 1.5 1 1 0 1 1 1 0 50S ribosome-binding GTPase Sigma54_activat PF00158.21 KLO16339.1 - 0.061 12.8 0.0 0.085 12.3 0.0 1.2 1 0 0 1 1 1 0 Sigma-54 interaction domain ABC_tran PF00005.22 KLO16339.1 - 0.062 13.6 0.0 0.12 12.7 0.0 1.4 1 0 0 1 1 1 0 ABC transporter AAA_30 PF13604.1 KLO16339.1 - 0.067 12.7 0.0 0.092 12.3 0.0 1.2 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.7 KLO16339.1 - 0.085 11.9 0.0 0.12 11.4 0.0 1.2 1 0 0 1 1 1 0 Zeta toxin Viral_helicase1 PF01443.13 KLO16339.1 - 0.088 12.3 0.0 0.13 11.7 0.0 1.2 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase UPF0079 PF02367.12 KLO16339.1 - 0.092 12.3 0.0 0.18 11.4 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 FtsK_SpoIIIE PF01580.13 KLO16339.1 - 0.14 11.6 0.0 0.26 10.7 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA PF00004.24 KLO16339.1 - 0.14 12.3 0.0 0.33 11.1 0.0 1.6 2 0 0 2 2 1 0 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.1 KLO16339.1 - 0.15 11.7 0.0 0.27 11.0 0.0 1.3 1 0 0 1 1 1 0 Part of AAA domain DUF2075 PF09848.4 KLO16339.1 - 0.2 10.5 0.0 0.31 9.9 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Mago-bind PF09282.5 KLO16341.1 - 4.9e-12 45.1 1.1 4.9e-12 45.1 0.7 1.8 2 0 0 2 2 2 1 Mago binding SDA1 PF05285.7 KLO16341.1 - 0.00036 19.9 7.9 0.00041 19.7 5.4 1.1 1 0 0 1 1 1 1 SDA1 eIF3_subunit PF08597.5 KLO16341.1 - 0.16 11.5 17.9 0.21 11.1 12.4 1.1 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit U79_P34 PF03064.11 KLO16341.1 - 5.8 6.3 12.0 8.8 5.7 8.3 1.3 1 0 0 1 1 1 0 HSV U79 / HCMV P34 DUF1640 PF07798.6 KLO16342.1 - 3.6e-11 43.4 2.3 5e-11 42.9 1.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1640) Mito_fiss_reg PF05308.6 KLO16342.1 - 2.2 7.5 9.5 9.2 5.5 6.4 2.2 1 1 0 1 1 1 0 Mitochondrial fission regulator WD40 PF00400.27 KLO16343.1 - 1.9e-57 189.1 35.2 1.2e-10 40.8 0.1 11.7 12 0 0 12 12 12 10 WD domain, G-beta repeat DEAD PF00270.24 KLO16344.1 - 2.3e-13 49.9 0.0 8.8e-13 48.0 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KLO16344.1 - 2.3e-10 40.1 0.0 4.9e-10 39.1 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain RRM_1 PF00076.17 KLO16345.1 - 1.2e-10 40.9 0.0 4.6e-06 26.1 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KLO16345.1 - 3.9e-10 39.5 0.0 3.8e-09 36.4 0.0 2.2 1 1 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) NTR2 PF15458.1 KLO16345.1 - 0.067 12.4 0.0 0.11 11.7 0.0 1.3 1 0 0 1 1 1 0 Nineteen complex-related protein 2 Aminotran_1_2 PF00155.16 KLO16346.1 - 5.8e-40 137.3 0.0 6.8e-40 137.1 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.15 KLO16346.1 - 1.2e-06 27.0 0.0 1.8e-06 26.4 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.12 KLO16346.1 - 4.1e-06 26.0 0.1 7.4e-06 25.2 0.0 1.4 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Beta_elim_lyase PF01212.16 KLO16346.1 - 0.0011 18.1 0.0 0.0018 17.4 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.14 KLO16346.1 - 0.011 14.5 0.0 0.017 13.8 0.0 1.3 1 0 0 1 1 1 0 Aminotransferase class-V WD40 PF00400.27 KLO16347.1 - 2.4e-18 65.2 10.1 0.00016 21.3 0.3 5.2 5 0 0 5 5 5 4 WD domain, G-beta repeat eIF2A PF08662.6 KLO16347.1 - 3.4e-06 26.9 0.0 0.0077 15.9 0.0 3.1 2 1 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A Glyco_hydro_16 PF00722.16 KLO16349.1 - 3.4e-07 29.7 0.0 6e-07 28.9 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 zf-CCHC PF00098.18 KLO16350.1 - 5.6e-07 29.1 28.1 0.00033 20.4 1.0 4.9 5 0 0 5 5 5 4 Zinc knuckle DUF3635 PF12330.3 KLO16351.1 - 3.5e-22 78.3 0.1 8e-22 77.1 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3635) Pkinase PF00069.20 KLO16351.1 - 0.014 14.5 0.0 0.027 13.6 0.0 1.4 1 0 0 1 1 1 0 Protein kinase domain Sld5 PF05916.6 KLO16352.1 - 1.6e-17 63.7 0.2 2.2e-17 63.2 0.1 1.2 1 0 0 1 1 1 1 GINS complex protein Phytase-like PF13449.1 KLO16353.1 - 8.1e-25 87.7 8.9 7.6e-24 84.5 6.2 2.3 1 1 0 1 1 1 1 Esterase-like activity of phytase Phytase-like PF13449.1 KLO16354.1 - 1.5e-25 90.1 0.0 3.1e-25 89.1 0.0 1.4 2 0 0 2 2 2 1 Esterase-like activity of phytase P21-Arc PF04062.9 KLO16356.1 - 2.5e-71 239.0 0.0 2.7e-71 238.9 0.0 1.0 1 0 0 1 1 1 1 ARP2/3 complex ARPC3 (21 kDa) subunit NOB1_Zn_bind PF08772.6 KLO16357.1 - 1e-27 95.7 0.9 1.9e-27 94.9 0.6 1.4 1 0 0 1 1 1 1 Nin one binding (NOB1) Zn-ribbon like zf-ribbon_3 PF13248.1 KLO16357.1 - 0.47 9.7 6.3 0.93 8.7 4.4 1.5 1 0 0 1 1 1 0 zinc-ribbon domain zf-NADH-PPase PF09297.6 KLO16357.1 - 0.51 9.8 3.6 0.61 9.6 0.1 2.4 2 0 0 2 2 2 0 NADH pyrophosphatase zinc ribbon domain Iso_dh PF00180.15 KLO16358.1 - 4.5e-126 420.4 0.0 5.4e-126 420.2 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase MRC1 PF09444.5 KLO16360.1 - 1.3e-17 64.4 24.7 1.3e-17 64.4 17.1 6.3 6 1 1 7 7 7 1 MRC1-like domain DUF884 PF05959.6 KLO16360.1 - 0.091 12.0 0.0 0.17 11.1 0.0 1.3 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF884) adh_short PF00106.20 KLO16361.1 - 3.1e-31 108.5 0.7 1.3e-30 106.5 0.2 2.1 2 1 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 KLO16361.1 - 1.4e-13 50.9 1.0 2.1e-12 47.0 0.6 2.3 1 1 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 KLO16361.1 - 3.9e-09 36.6 0.1 5.2e-09 36.2 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 KLO16361.1 - 0.00018 21.5 0.1 0.00053 20.0 0.0 1.8 2 1 0 2 2 2 1 NADH(P)-binding Epimerase PF01370.16 KLO16361.1 - 0.00066 19.1 1.2 0.0036 16.7 0.4 2.3 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family GVQW PF13900.1 KLO16361.1 - 0.14 12.2 3.7 0.081 12.9 0.8 1.9 2 0 0 2 2 2 0 Putative binding domain Cyclin PF08613.6 KLO16362.1 - 3.5e-40 137.8 0.0 3.5e-40 137.8 0.0 2.1 2 0 0 2 2 2 1 Cyclin Cyclin_N PF00134.18 KLO16362.1 - 0.1 12.1 0.0 0.16 11.5 0.0 1.3 1 0 0 1 1 1 0 Cyclin, N-terminal domain Alpha-amylase_C PF02806.13 KLO16363.1 - 8.6e-25 86.7 0.1 2.7e-24 85.1 0.1 1.9 1 0 0 1 1 1 1 Alpha amylase, C-terminal all-beta domain CBM_48 PF02922.13 KLO16363.1 - 7.4e-16 57.9 0.0 2.1e-15 56.5 0.0 1.8 1 0 0 1 1 1 1 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) Alpha-amylase PF00128.19 KLO16363.1 - 5.9e-15 55.4 0.0 1.1e-12 47.9 0.0 2.5 1 1 1 2 2 2 2 Alpha amylase, catalytic domain Miro PF08477.8 KLO16364.1 - 4e-07 30.5 0.2 4.2e-06 27.2 0.2 2.2 1 1 0 1 1 1 1 Miro-like protein Ras PF00071.17 KLO16364.1 - 5.4e-06 25.8 0.0 0.0021 17.4 0.0 2.2 2 0 0 2 2 2 2 Ras family Septin PF00735.13 KLO16364.1 - 0.0022 17.0 0.0 0.0035 16.3 0.0 1.4 1 0 0 1 1 1 1 Septin AAA_33 PF13671.1 KLO16364.1 - 0.0035 17.2 0.0 0.0065 16.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 KLO16364.1 - 0.0082 16.9 0.0 0.013 16.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 KLO16364.1 - 0.011 15.7 0.0 0.02 14.9 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain Viral_helicase1 PF01443.13 KLO16364.1 - 0.011 15.2 0.2 0.028 13.9 0.0 1.7 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase AAA_22 PF13401.1 KLO16364.1 - 0.018 15.2 0.3 0.056 13.5 0.1 1.7 1 1 1 2 2 2 0 AAA domain ABC_tran PF00005.22 KLO16364.1 - 0.025 14.8 0.1 0.092 13.0 0.1 1.5 1 1 0 1 1 1 0 ABC transporter MobB PF03205.9 KLO16364.1 - 0.046 13.4 0.1 0.083 12.6 0.1 1.4 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B ATP_bind_1 PF03029.12 KLO16364.1 - 0.048 13.2 0.1 3.2 7.2 0.0 2.1 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein PduV-EutP PF10662.4 KLO16364.1 - 0.064 12.7 0.0 0.19 11.1 0.0 1.6 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation Arch_ATPase PF01637.13 KLO16364.1 - 0.1 12.2 0.0 0.16 11.6 0.0 1.3 1 0 0 1 1 1 0 Archaeal ATPase Picorna_P3A PF06363.6 KLO16364.1 - 0.11 12.5 0.0 0.32 11.0 0.0 1.7 2 0 0 2 2 2 0 Picornaviridae P3A protein NACHT PF05729.7 KLO16364.1 - 0.11 12.1 0.2 0.19 11.3 0.1 1.4 1 0 0 1 1 1 0 NACHT domain Arf PF00025.16 KLO16364.1 - 0.14 11.3 0.0 1.9 7.6 0.0 2.0 2 0 0 2 2 2 0 ADP-ribosylation factor family RasGEF PF00617.14 KLO16365.1 - 3.7e-25 88.7 0.0 6.4e-25 87.9 0.0 1.4 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.15 KLO16365.1 - 8.1e-12 45.1 0.0 1.8e-11 44.0 0.0 1.5 1 0 0 1 1 1 1 RasGEF N-terminal motif Miro PF08477.8 KLO16365.1 - 1.6e-05 25.4 0.0 0.0001 22.8 0.0 2.4 2 1 0 2 2 2 1 Miro-like protein Viral_helicase1 PF01443.13 KLO16365.1 - 0.0022 17.5 0.1 0.0045 16.5 0.1 1.5 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase AAA_33 PF13671.1 KLO16365.1 - 0.0025 17.6 0.7 0.084 12.7 0.0 2.5 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.18 KLO16365.1 - 0.049 13.6 0.0 0.15 12.0 0.0 1.8 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_22 PF13401.1 KLO16365.1 - 0.09 12.9 0.0 0.38 10.8 0.0 2.0 1 0 0 1 1 1 0 AAA domain DUF258 PF03193.11 KLO16365.1 - 0.19 10.9 0.0 0.37 9.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 SH3_1 PF00018.23 KLO16366.1 - 7.1e-22 76.5 0.0 6.6e-11 41.4 0.0 2.7 2 0 0 2 2 2 2 SH3 domain SH3_2 PF07653.12 KLO16366.1 - 7.4e-16 57.3 0.0 2.1e-11 43.1 0.0 2.4 2 0 0 2 2 2 2 Variant SH3 domain SH3_9 PF14604.1 KLO16366.1 - 1.7e-14 53.0 0.5 2.3e-08 33.4 0.0 2.9 3 0 0 3 3 3 2 Variant SH3 domain PX PF00787.19 KLO16366.1 - 3.3e-07 30.1 0.0 8.2e-07 28.8 0.0 1.6 1 0 0 1 1 1 1 PX domain Not3 PF04065.10 KLO16367.1 - 9.1e-93 309.8 21.5 1.3e-92 309.3 14.9 1.2 1 0 0 1 1 1 1 Not1 N-terminal domain, CCR4-Not complex component NOT2_3_5 PF04153.13 KLO16367.1 - 4.2e-44 149.6 6.3 1.7e-43 147.6 4.4 2.2 1 0 0 1 1 1 1 NOT2 / NOT3 / NOT5 family Syntaxin PF00804.20 KLO16367.1 - 0.25 11.4 20.0 1.7 8.8 2.8 3.1 2 1 1 3 3 3 0 Syntaxin Ribosomal_L12 PF00542.14 KLO16368.1 - 2.4e-18 65.8 7.1 3.4e-17 62.2 2.9 2.4 2 1 0 2 2 2 2 Ribosomal protein L7/L12 C-terminal domain DUF2562 PF10814.3 KLO16368.1 - 0.01 15.7 0.1 0.01 15.7 0.0 1.9 3 0 0 3 3 3 0 Protein of unknown function (DUF2562) INTS2 PF14750.1 KLO16368.1 - 0.064 10.7 0.0 0.078 10.4 0.0 1.1 1 0 0 1 1 1 0 Integrator complex subunit 2 MARVEL PF01284.18 KLO16369.1 - 0.34 10.7 12.0 0.029 14.1 4.4 2.0 2 1 0 2 2 2 0 Membrane-associating domain DUF373 PF04123.8 KLO16369.1 - 6.4 5.6 7.2 6.4 5.6 4.2 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF373) TPR_11 PF13414.1 KLO16371.1 - 2.3e-16 59.1 11.9 1e-11 44.3 1.1 2.3 2 0 0 2 2 2 2 TPR repeat TPR_1 PF00515.23 KLO16371.1 - 8.9e-09 34.5 10.8 0.00023 20.6 0.1 4.0 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.12 KLO16371.1 - 2.2e-07 30.2 10.9 0.00091 18.9 0.1 4.3 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.1 KLO16371.1 - 0.0015 19.0 0.3 0.0015 19.0 0.2 3.3 2 2 2 4 4 4 1 Tetratricopeptide repeat TPR_16 PF13432.1 KLO16371.1 - 0.0045 17.6 5.0 0.05 14.2 0.1 3.3 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_17 PF13431.1 KLO16371.1 - 0.0049 16.9 4.4 0.62 10.4 0.1 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.1 KLO16371.1 - 0.011 15.6 3.6 0.92 9.4 1.2 2.7 2 1 1 3 3 3 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 KLO16371.1 - 0.035 13.9 0.1 0.1 12.5 0.1 1.8 1 0 0 1 1 1 0 Fis1 C-terminal tetratricopeptide repeat TPR_19 PF14559.1 KLO16371.1 - 0.08 13.2 1.2 0.24 11.7 0.1 2.1 2 1 1 3 3 3 0 Tetratricopeptide repeat DAO PF01266.19 KLO16372.1 - 1.1e-31 110.0 0.0 3.2e-31 108.5 0.0 1.6 1 1 0 1 1 1 1 FAD dependent oxidoreductase NDUFA12 PF05071.11 KLO16373.1 - 3.1e-25 88.6 1.4 4.7e-25 88.0 1.0 1.2 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase subunit NDUFA12 Ribosomal_L18_c PF14204.1 KLO16373.1 - 0.024 15.1 0.0 0.036 14.6 0.0 1.3 1 0 0 1 1 1 0 Ribosomal L18 C-terminal region B12D PF06522.6 KLO16374.1 - 4.1e-13 48.8 0.2 5.4e-13 48.4 0.1 1.1 1 0 0 1 1 1 1 NADH-ubiquinone reductase complex 1 MLRQ subunit Aldo_ket_red PF00248.16 KLO16375.1 - 1.1e-42 145.8 0.0 1.4e-42 145.4 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family TPR_11 PF13414.1 KLO16376.1 - 3e-37 126.0 3.8 1.9e-17 62.6 0.0 3.3 3 0 0 3 3 3 3 TPR repeat TPR_1 PF00515.23 KLO16376.1 - 1.2e-28 97.4 7.1 1.9e-07 30.3 0.0 5.4 5 0 0 5 5 5 5 Tetratricopeptide repeat TPR_2 PF07719.12 KLO16376.1 - 1.3e-22 77.8 7.7 0.00025 20.7 0.0 5.6 5 0 0 5 5 5 5 Tetratricopeptide repeat TPR_12 PF13424.1 KLO16376.1 - 4.1e-18 65.0 2.7 8.8e-13 48.0 0.2 3.7 2 1 2 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.1 KLO16376.1 - 5.1e-16 58.8 0.5 2e-05 25.1 0.0 3.9 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_19 PF14559.1 KLO16376.1 - 5.6e-13 49.0 1.5 8.2e-07 29.2 0.1 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.1 KLO16376.1 - 2.8e-11 42.3 2.3 0.037 13.8 0.0 5.3 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_17 PF13431.1 KLO16376.1 - 4.8e-11 41.9 1.4 0.0033 17.4 0.0 4.5 3 2 1 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.1 KLO16376.1 - 7.2e-11 41.0 11.2 0.0019 17.8 0.0 5.6 5 1 1 6 6 6 3 Tetratricopeptide repeat TPR_14 PF13428.1 KLO16376.1 - 1.7e-10 40.5 0.0 0.27 11.9 0.0 5.3 2 2 3 5 5 5 3 Tetratricopeptide repeat TPR_6 PF13174.1 KLO16376.1 - 2.3e-07 30.8 1.4 2.4 8.7 0.0 5.5 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_9 PF13371.1 KLO16376.1 - 3.9e-07 29.8 0.2 0.00011 21.9 0.0 3.3 2 1 2 4 4 4 2 Tetratricopeptide repeat Apc3 PF12895.2 KLO16376.1 - 5.2e-06 26.5 0.8 0.00013 22.0 0.1 2.5 2 1 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_10 PF13374.1 KLO16376.1 - 0.0099 15.7 0.0 0.3 11.0 0.0 3.0 3 0 0 3 3 3 1 Tetratricopeptide repeat BTAD PF03704.12 KLO16376.1 - 0.05 13.8 0.5 1.7 8.9 0.0 2.2 2 0 0 2 2 2 0 Bacterial transcriptional activator domain Fungal_trans PF04082.13 KLO16377.1 - 8.1e-21 74.0 0.7 1.3e-20 73.3 0.5 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KLO16377.1 - 9.8e-06 25.3 8.6 2.2e-05 24.2 5.9 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Nup160 PF11715.3 KLO16378.1 - 2e-33 115.3 1.1 1.5e-32 112.4 0.1 2.2 2 0 0 2 2 2 2 Nucleoporin Nup120/160 Cyt-b5 PF00173.23 KLO16380.1 - 2.9e-11 43.0 0.1 4.8e-11 42.2 0.1 1.4 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain RGS PF00615.14 KLO16381.1 - 7.9e-37 125.9 0.0 1.8e-36 124.7 0.0 1.7 1 0 0 1 1 1 1 Regulator of G protein signaling domain DEP PF00610.16 KLO16381.1 - 8.7e-14 51.0 0.0 1.9e-06 27.5 0.0 3.0 2 1 0 2 2 2 2 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) Adap_comp_sub PF00928.16 KLO16382.1 - 1.7e-56 191.2 0.0 2.1e-56 190.9 0.0 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.15 KLO16382.1 - 0.00017 21.3 0.0 0.0003 20.5 0.0 1.3 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Sod_Fe_C PF02777.13 KLO16383.1 - 2.3e-14 53.1 0.1 2.3e-08 33.8 0.0 2.4 2 0 0 2 2 2 2 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.17 KLO16383.1 - 0.063 13.5 0.0 0.14 12.4 0.0 1.7 1 0 0 1 1 1 0 Iron/manganese superoxide dismutases, alpha-hairpin domain DAD PF02109.11 KLO16384.1 - 2e-47 159.9 0.9 2.3e-47 159.7 0.6 1.0 1 0 0 1 1 1 1 DAD family DUF1748 PF08520.5 KLO16385.1 - 2.1e-27 94.5 0.0 2.3e-27 94.4 0.0 1.0 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1748) Isochorismatase PF00857.15 KLO16386.1 - 1e-30 106.9 0.1 1.7e-30 106.2 0.1 1.3 1 1 0 1 1 1 1 Isochorismatase family Glyco_transf_4 PF13439.1 KLO16386.1 - 0.081 12.6 0.0 0.32 10.7 0.0 1.8 2 0 0 2 2 2 0 Glycosyltransferase Family 4 CENP-F_leu_zip PF10473.4 KLO16387.1 - 3.4 7.5 24.8 0.12 12.2 0.3 3.0 2 1 0 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF3445 PF11927.3 KLO16388.1 - 2.2e-60 204.1 0.0 1.1e-58 198.5 0.0 2.1 1 1 0 1 1 1 1 Protein of unknown function (DUF3445) TSSC4 PF15264.1 KLO16388.1 - 0.061 13.7 0.4 0.061 13.7 0.3 1.7 2 0 0 2 2 2 0 Tumour suppressing sub-chromosomal transferable candidate 4 Filament PF00038.16 KLO16389.1 - 0.00076 19.0 29.1 0.00076 19.0 20.2 3.0 3 0 0 3 3 3 2 Intermediate filament protein WEMBL PF05701.6 KLO16389.1 - 0.00092 17.7 52.4 0.00092 17.7 36.3 2.2 1 1 0 1 1 1 1 Weak chloroplast movement under blue light IncA PF04156.9 KLO16390.1 - 0.00047 19.8 19.6 0.00047 19.8 13.6 4.7 2 1 2 5 5 5 2 IncA protein LOH1CR12 PF10158.4 KLO16390.1 - 4 7.2 9.8 0.93 9.2 0.3 3.8 2 1 2 4 4 4 0 Tumour suppressor protein Med28 PF11594.3 KLO16391.1 - 0.012 15.8 0.2 0.015 15.5 0.2 1.2 1 0 0 1 1 1 0 Mediator complex subunit 28 Atg14 PF10186.4 KLO16391.1 - 0.023 13.6 1.7 0.028 13.3 1.2 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 HrpB7 PF09486.5 KLO16391.1 - 0.028 14.3 1.6 0.03 14.2 0.4 1.5 1 1 0 1 1 1 0 Bacterial type III secretion protein (HrpB7) DIT1_PvcA PF05141.7 KLO16391.1 - 0.074 12.3 0.1 0.076 12.3 0.1 1.1 1 0 0 1 1 1 0 Pyoverdine/dityrosine biosynthesis protein IL2 PF00715.12 KLO16391.1 - 0.11 12.2 0.1 0.14 11.8 0.1 1.3 1 0 0 1 1 1 0 Interleukin 2 Reo_sigmaC PF04582.7 KLO16391.1 - 0.15 11.2 0.5 0.17 11.0 0.3 1.0 1 0 0 1 1 1 0 Reovirus sigma C capsid protein CENP-F_leu_zip PF10473.4 KLO16391.1 - 0.24 11.2 4.4 0.91 9.3 3.0 1.8 1 1 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 RGS PF00615.14 KLO16392.1 - 9e-14 51.5 0.2 2.3e-13 50.2 0.0 1.8 2 0 0 2 2 2 1 Regulator of G protein signaling domain DEP PF00610.16 KLO16392.1 - 0.013 15.1 0.0 0.35 10.6 0.0 2.5 2 0 0 2 2 2 0 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) CSF-1 PF05337.6 KLO16393.1 - 0.001 18.4 0.2 0.0016 17.8 0.1 1.2 1 0 0 1 1 1 1 Macrophage colony stimulating factor-1 (CSF-1) SecIII_SopE_N PF05364.9 KLO16393.1 - 0.22 11.3 2.0 0.42 10.4 1.4 1.4 1 0 0 1 1 1 0 Salmonella type III secretion SopE effector N-terminus bZIP_1 PF00170.16 KLO16396.1 - 5.1e-11 42.3 7.8 5.1e-11 42.3 5.4 1.8 2 0 0 2 2 2 1 bZIP transcription factor Aft1_HRA PF11786.3 KLO16396.1 - 1.2e-09 38.2 15.4 6.7e-09 35.8 10.7 2.3 1 1 0 1 1 1 1 Aft1 HRA domain bZIP_2 PF07716.10 KLO16396.1 - 6.9e-06 25.7 9.1 6.9e-06 25.7 6.3 2.6 2 0 0 2 2 2 1 Basic region leucine zipper Aft1_OSA PF11785.3 KLO16396.1 - 0.00015 22.2 4.2 0.00015 22.2 2.9 4.6 4 2 0 5 5 5 1 Aft1 osmotic stress response (OSM) domain DUF812 PF05667.6 KLO16399.1 - 0.0061 15.1 8.3 0.0092 14.5 5.8 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF812) DEAD PF00270.24 KLO16401.1 - 4.8e-17 61.9 0.0 7.4e-17 61.3 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KLO16401.1 - 9.6e-11 41.4 0.0 5.2e-10 39.0 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 KLO16401.1 - 2.2e-05 24.3 0.2 8.1e-05 22.5 0.0 1.9 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Helicase_C_2 PF13307.1 KLO16401.1 - 0.00094 19.1 0.0 1.1 9.2 0.0 2.4 1 1 1 2 2 2 2 Helicase C-terminal domain SecA_DEAD PF07517.9 KLO16401.1 - 0.037 13.3 0.0 0.077 12.2 0.0 1.5 1 0 0 1 1 1 0 SecA DEAD-like domain COX7a PF02238.10 KLO16405.1 - 0.031 13.9 0.1 0.073 12.8 0.1 1.6 1 0 0 1 1 1 0 Cytochrome c oxidase subunit VIIa HATPase_c_5 PF14501.1 KLO16406.1 - 0.12 12.1 0.0 0.18 11.5 0.0 1.3 1 0 0 1 1 1 0 GHKL domain vMSA PF00695.14 KLO16407.1 - 0.014 14.6 0.9 0.018 14.2 0.6 1.1 1 0 0 1 1 1 0 Major surface antigen from hepadnavirus Tox-WTIP PF15654.1 KLO16409.1 - 0.038 13.6 1.4 0.038 13.6 0.9 2.3 1 1 1 2 2 2 0 Toxin with a conserved tryptophan and TIP tripeptide motif Pyr_redox_3 PF13738.1 KLO16411.1 - 1.3e-14 54.7 0.0 2.4e-14 53.9 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KLO16411.1 - 1.7e-09 37.5 0.0 3.9e-09 36.3 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FMO-like PF00743.14 KLO16411.1 - 4.8e-08 31.6 0.2 0.01 14.0 0.1 3.3 2 2 0 2 2 2 2 Flavin-binding monooxygenase-like NAD_binding_9 PF13454.1 KLO16411.1 - 1.3e-05 25.0 0.3 0.00026 20.8 0.0 3.0 4 0 0 4 4 4 1 FAD-NAD(P)-binding Thi4 PF01946.12 KLO16411.1 - 0.021 13.9 0.1 0.15 11.1 0.0 2.1 2 0 0 2 2 2 0 Thi4 family K_oxygenase PF13434.1 KLO16411.1 - 0.062 12.2 0.1 18 4.0 0.0 3.0 3 0 0 3 3 3 0 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 KLO16411.1 - 0.13 12.1 0.0 1.4 8.7 0.0 2.1 1 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DUF4148 PF13663.1 KLO16412.1 - 0.015 15.1 0.0 0.055 13.3 0.0 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4148) Sugar_tr PF00083.19 KLO16414.1 - 4.5e-34 117.8 17.7 2e-32 112.3 12.3 2.0 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KLO16414.1 - 6.9e-21 74.3 31.7 1.6e-13 50.1 7.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Tox-WTIP PF15654.1 KLO16417.1 - 0.056 13.0 0.0 0.14 11.7 0.0 1.6 1 0 0 1 1 1 0 Toxin with a conserved tryptophan and TIP tripeptide motif Gal-bind_lectin PF00337.17 KLO16421.1 - 0.15 11.4 0.5 0.24 10.7 0.3 1.4 1 1 0 1 1 1 0 Galactoside-binding lectin DDE_1 PF03184.14 KLO16423.1 - 5.7e-18 64.8 0.1 7.1e-18 64.5 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_3 PF13358.1 KLO16423.1 - 0.01 15.6 0.0 0.03 14.0 0.0 1.8 2 0 0 2 2 2 0 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.11 KLO16423.1 - 0.076 12.8 0.0 0.21 11.4 0.0 1.7 1 0 0 1 1 1 0 Tc5 transposase DNA-binding domain Retro_M PF02813.9 KLO16423.1 - 0.083 13.0 0.0 0.14 12.3 0.0 1.3 1 0 0 1 1 1 0 Retroviral M domain bPH_5 PF10882.3 KLO16428.1 - 0.044 13.5 0.0 0.066 13.0 0.0 1.2 1 0 0 1 1 1 0 Bacterial PH domain SLBP_RNA_bind PF15247.1 KLO16428.1 - 0.068 12.9 0.4 0.12 12.1 0.3 1.5 1 0 0 1 1 1 0 Histone RNA hairpin-binding protein RNA-binding domain RRM_6 PF14259.1 KLO16429.1 - 1.8e-05 24.6 0.0 2.4e-05 24.1 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 KLO16429.1 - 0.0059 16.2 0.0 0.0085 15.7 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF1118 PF06549.7 KLO16430.1 - 4.9 7.3 9.4 6.5 6.9 6.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1118) DDE_1 PF03184.14 KLO16433.1 - 1.8e-11 43.6 0.0 2e-11 43.4 0.0 1.0 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_1 PF03184.14 KLO16434.1 - 2.6e-14 52.9 0.0 3.2e-14 52.6 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease Phage_30_3 PF08010.6 KLO16438.1 - 0.49 9.8 2.8 5 6.6 0.1 2.8 2 2 1 3 3 3 0 Bacteriophage protein GP30.3 Tox-WTIP PF15654.1 KLO16439.1 - 0.067 12.8 1.7 1 9.0 0.3 2.5 2 0 0 2 2 2 0 Toxin with a conserved tryptophan and TIP tripeptide motif Pro-kuma_activ PF09286.6 KLO16441.1 - 3.4e-37 127.6 0.0 1.9e-36 125.2 0.0 2.0 2 0 0 2 2 2 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.17 KLO16441.1 - 3.6e-12 46.0 2.1 3.8e-12 45.9 0.3 1.6 1 1 1 2 2 2 1 Subtilase family F-box-like PF12937.2 KLO16442.1 - 0.018 14.7 0.1 0.041 13.6 0.1 1.6 1 0 0 1 1 1 0 F-box-like zf-AD PF07776.10 KLO16442.1 - 0.28 11.1 2.5 0.31 11.0 0.0 2.4 2 0 0 2 2 2 0 Zinc-finger associated domain (zf-AD) DUF1677 PF07911.8 KLO16443.1 - 0.052 13.7 0.0 0.15 12.2 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1677) Fer4_12 PF13353.1 KLO16443.1 - 0.14 12.2 0.2 12 5.9 0.0 2.4 2 0 0 2 2 2 0 4Fe-4S single cluster domain ICL PF00463.16 KLO16444.1 - 0.039 12.1 0.0 0.082 11.1 0.0 1.5 1 1 1 2 2 2 0 Isocitrate lyase family Senescence PF06911.7 KLO16446.1 - 9.9e-13 48.1 0.8 9.9e-13 48.1 0.6 1.8 2 0 0 2 2 2 1 Senescence-associated protein SR-25 PF10500.4 KLO16446.1 - 0.084 12.3 4.8 0.096 12.1 0.5 2.3 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein CIMR PF00878.13 KLO16447.1 - 9.3e-11 41.6 0.1 3.1e-05 23.7 0.0 2.2 2 0 0 2 2 2 2 Cation-independent mannose-6-phosphate receptor repeat ATG27 PF09451.5 KLO16447.1 - 0.014 14.6 0.1 0.43 9.7 0.0 2.2 2 0 0 2 2 2 0 Autophagy-related protein 27 zf-DBF PF07535.7 KLO16449.1 - 7.7e-20 70.3 0.8 1.6e-19 69.2 0.6 1.6 1 0 0 1 1 1 1 DBF zinc finger Dfp1_Him1_M PF08630.5 KLO16449.1 - 8e-19 67.6 0.0 1.9e-18 66.4 0.0 1.6 1 0 0 1 1 1 1 Dfp1/Him1, central region BRCT PF00533.21 KLO16449.1 - 0.00036 20.6 0.0 0.00087 19.3 0.0 1.6 1 1 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.2 KLO16449.1 - 0.022 14.5 0.0 0.28 11.0 0.0 2.4 2 0 0 2 2 2 0 twin BRCT domain DUF4620 PF15399.1 KLO16449.1 - 0.051 13.7 0.2 0.12 12.4 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4620) Red1 PF07964.6 KLO16449.1 - 0.061 11.4 0.1 0.11 10.6 0.1 1.3 1 0 0 1 1 1 0 Rec10 / Red1 EmrE PF13536.1 KLO16453.1 - 0.057 13.6 0.0 0.067 13.4 0.0 1.0 1 0 0 1 1 1 0 Multidrug resistance efflux transporter AP_endonuc_2 PF01261.19 KLO16454.1 - 2.4e-33 115.2 0.3 7e-33 113.7 0.0 1.9 3 0 0 3 3 3 1 Xylose isomerase-like TIM barrel Costars PF14705.1 KLO16454.1 - 0.046 13.7 0.0 0.67 9.9 0.0 2.4 2 0 0 2 2 2 0 Costars COG4 PF08318.7 KLO16455.1 - 0.029 13.1 0.0 0.034 12.8 0.0 1.1 1 0 0 1 1 1 0 COG4 transport protein DUF3377 PF11857.3 KLO16456.1 - 2.3 7.9 4.7 1.1 8.9 0.5 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3377) G-alpha PF00503.15 KLO16457.1 - 2.7e-109 365.4 0.0 3.2e-109 365.1 0.0 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 KLO16457.1 - 2.3e-09 36.7 0.1 8.7e-06 25.0 0.0 2.4 2 0 0 2 2 2 2 ADP-ribosylation factor family AAA_29 PF13555.1 KLO16457.1 - 0.0053 16.2 0.0 0.011 15.2 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain KOW PF00467.24 KLO16458.1 - 2.8e-14 52.1 16.6 2.5e-05 23.8 0.2 5.6 5 0 0 5 5 5 5 KOW motif Spt5-NGN PF03439.8 KLO16458.1 - 5.9e-12 45.1 0.0 1.2e-11 44.2 0.0 1.5 1 0 0 1 1 1 1 Early transcription elongation factor of RNA pol II, NGN section Ribosomal_L9_N PF01281.14 KLO16458.1 - 1.6 7.9 5.7 21 4.4 0.1 3.6 2 1 1 3 3 3 0 Ribosomal protein L9, N-terminal domain HAS-barrel PF09378.5 KLO16458.1 - 2.1 8.3 4.6 6.6 6.7 0.0 3.0 3 0 0 3 3 3 0 HAS barrel domain p450 PF00067.17 KLO16459.1 - 6.9e-49 166.6 0.0 1.2e-47 162.5 0.0 2.3 1 1 0 1 1 1 1 Cytochrome P450 DUF3505 PF12013.3 KLO16461.1 - 4e-07 30.2 0.2 4e-07 30.2 0.1 2.8 2 0 0 2 2 2 1 Protein of unknown function (DUF3505) Helicase_C PF00271.26 KLO16461.1 - 8e-07 28.8 0.0 2e-06 27.5 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 KLO16461.1 - 6.2e-06 25.8 0.1 1.1e-05 24.9 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.10 KLO16461.1 - 0.0014 18.4 0.0 0.0047 16.7 0.0 1.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit T4SS-DNA_transf PF02534.9 KLO16461.1 - 0.0016 17.0 0.0 0.0025 16.4 0.0 1.2 1 0 0 1 1 1 1 Type IV secretory system Conjugative DNA transfer Macoilin PF09726.4 KLO16461.1 - 0.18 10.0 9.4 0.27 9.4 6.5 1.1 1 0 0 1 1 1 0 Transmembrane protein zf-MYND PF01753.13 KLO16462.1 - 1e-08 34.9 13.4 1.8e-08 34.0 9.3 1.5 1 0 0 1 1 1 1 MYND finger PolC_DP2 PF03833.8 KLO16462.1 - 0.73 7.4 4.3 1 6.9 3.0 1.1 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 IncA PF04156.9 KLO16463.1 - 1.2e-05 25.0 6.5 0.0011 18.5 0.1 2.5 2 1 1 3 3 3 2 IncA protein DUF3040 PF11239.3 KLO16463.1 - 0.033 14.2 0.1 0.082 12.9 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3040) Mer2 PF09074.5 KLO16463.1 - 0.044 13.6 4.6 0.11 12.4 0.3 2.5 2 1 0 2 2 2 0 Mer2 Acyl-CoA_dh_2 PF08028.6 KLO16463.1 - 0.093 12.9 0.3 14 5.8 0.0 3.0 4 0 0 4 4 4 0 Acyl-CoA dehydrogenase, C-terminal domain IFT57 PF10498.4 KLO16463.1 - 0.11 11.2 8.8 0.15 10.7 1.0 2.5 2 1 0 2 2 2 0 Intra-flagellar transport protein 57 DUF4231 PF14015.1 KLO16463.1 - 0.39 10.7 2.2 0.73 9.8 1.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4231) Mating_N PF12731.2 KLO16463.1 - 1.4 8.8 7.3 0.36 10.7 0.8 3.1 2 1 2 4 4 4 0 Mating-type protein beta 1 DUF4201 PF13870.1 KLO16463.1 - 5.2 6.4 8.6 0.8 9.1 2.0 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF4201) zf-MYND PF01753.13 KLO16464.1 - 2.7e-08 33.5 13.7 5.2e-08 32.6 9.5 1.5 1 0 0 1 1 1 1 MYND finger IncA PF04156.9 KLO16465.1 - 4.5e-05 23.1 6.0 0.001 18.7 0.4 2.5 1 1 1 2 2 2 2 IncA protein Syntaxin_2 PF14523.1 KLO16465.1 - 0.0026 17.7 0.2 0.058 13.4 0.0 2.9 3 0 0 3 3 3 1 Syntaxin-like protein Barstar PF01337.13 KLO16465.1 - 0.029 14.1 0.1 0.31 10.9 0.0 2.5 2 0 0 2 2 2 0 Barstar (barnase inhibitor) CLAG PF03805.8 KLO16465.1 - 0.052 10.8 0.2 0.074 10.3 0.1 1.1 1 0 0 1 1 1 0 Cytoadherence-linked asexual protein Aida_N PF08910.5 KLO16465.1 - 0.058 13.6 0.3 0.24 11.6 0.0 2.2 3 0 0 3 3 3 0 Aida N-terminus zf-C4pol PF14260.1 KLO16465.1 - 4.5 7.3 7.0 1 9.4 0.8 2.5 2 1 0 3 3 3 0 C4-type zinc-finger of DNA polymerase delta Mur_ligase_M PF08245.7 KLO16466.1 - 2.1e-11 44.2 0.0 3.8e-11 43.3 0.0 1.4 1 0 0 1 1 1 1 Mur ligase middle domain Phosphorylase PF00343.15 KLO16468.1 - 0 1016.5 0.0 0 1016.3 0.0 1.0 1 0 0 1 1 1 1 Carbohydrate phosphorylase HC2 PF07382.6 KLO16469.1 - 0.29 10.9 2.6 0.8 9.5 0.2 2.6 3 1 1 4 4 4 0 Histone H1-like nucleoprotein HC2 DUF1708 PF08101.6 KLO16470.1 - 3e-15 55.9 0.0 1.4e-10 40.5 0.0 2.6 2 1 0 2 2 2 2 Domain of unknown function (DUF1708) RhoGAP PF00620.22 KLO16470.1 - 0.2 11.2 0.0 0.49 9.9 0.0 1.7 1 1 0 1 1 1 0 RhoGAP domain FMN_dh PF01070.13 KLO16471.1 - 3.5e-108 361.6 0.0 4.8e-108 361.1 0.0 1.0 1 0 0 1 1 1 1 FMN-dependent dehydrogenase IMPDH PF00478.20 KLO16471.1 - 0.00088 18.2 0.1 0.0027 16.6 0.0 1.8 2 0 0 2 2 2 1 IMP dehydrogenase / GMP reductase domain ThiG PF05690.9 KLO16471.1 - 0.0017 17.4 0.2 0.02 13.9 0.0 2.4 2 1 1 3 3 3 1 Thiazole biosynthesis protein ThiG Glu_synthase PF01645.12 KLO16471.1 - 0.0023 16.9 0.0 0.0036 16.2 0.0 1.3 1 0 0 1 1 1 1 Conserved region in glutamate synthase PTR2 PF00854.16 KLO16472.1 - 5.4e-47 160.3 6.5 3.6e-46 157.6 4.5 2.1 1 1 0 1 1 1 1 POT family MFS_1 PF07690.11 KLO16472.1 - 3.6e-11 42.3 30.7 6.8e-11 41.4 17.3 3.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Amino_oxidase PF01593.19 KLO16473.1 - 4e-33 115.1 0.0 1e-20 74.2 0.0 2.1 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 KLO16473.1 - 1.5e-09 37.7 0.1 3.5e-09 36.5 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.9 KLO16473.1 - 0.002 16.6 0.4 0.0091 14.4 0.3 1.8 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox_3 PF13738.1 KLO16473.1 - 0.0047 17.0 0.1 0.011 15.7 0.1 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 KLO16473.1 - 0.032 13.3 0.6 2.9 6.9 0.1 2.3 2 0 0 2 2 2 0 Thi4 family FAD_binding_2 PF00890.19 KLO16473.1 - 0.085 11.6 0.0 0.14 10.9 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain FAD_binding_3 PF01494.14 KLO16473.1 - 0.13 11.2 0.4 0.2 10.6 0.3 1.2 1 0 0 1 1 1 0 FAD binding domain Pyr_redox PF00070.22 KLO16473.1 - 0.14 12.6 0.3 0.44 10.9 0.2 1.9 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase F-box-like PF12937.2 KLO16474.1 - 0.0003 20.4 0.0 0.00084 19.0 0.0 1.7 1 0 0 1 1 1 1 F-box-like LRR_8 PF13855.1 KLO16474.1 - 0.045 13.4 0.7 2.2 8.1 0.2 3.4 3 1 0 3 3 3 0 Leucine rich repeat F-box-like PF12937.2 KLO16475.1 - 0.0005 19.7 0.1 0.0014 18.2 0.1 1.8 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.2 KLO16475.1 - 0.23 11.1 8.3 27 4.4 0.3 4.9 4 1 0 4 4 4 0 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KLO16475.1 - 0.38 10.5 8.2 2.3 8.0 0.4 3.9 4 0 0 4 4 4 0 Leucine rich repeat F-box-like PF12937.2 KLO16476.1 - 1.2e-05 24.8 0.0 4e-05 23.2 0.0 2.0 1 1 0 1 1 1 1 F-box-like F-box-like PF12937.2 KLO16477.1 - 0.0004 20.0 0.0 0.0013 18.3 0.0 1.9 2 0 0 2 2 2 1 F-box-like LRR_7 PF13504.1 KLO16477.1 - 0.2 11.9 2.4 50 4.7 0.1 4.8 5 1 0 5 5 5 0 Leucine rich repeat Amino_oxidase PF01593.19 KLO16478.1 - 3.4e-37 128.5 0.2 5.7e-25 88.2 0.1 2.1 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 KLO16478.1 - 7.3e-10 38.7 0.0 2.3e-09 37.1 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 KLO16478.1 - 0.00062 19.8 0.2 0.0025 17.9 0.1 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 KLO16478.1 - 0.0041 15.6 0.4 0.0059 15.1 0.3 1.2 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox PF00070.22 KLO16478.1 - 0.031 14.6 0.3 0.093 13.1 0.2 1.8 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 KLO16478.1 - 0.035 13.1 0.2 0.083 11.9 0.2 1.5 1 0 0 1 1 1 0 Thi4 family Amino_oxidase PF01593.19 KLO16479.1 - 2.7e-34 119.0 0.0 4e-34 118.4 0.0 1.2 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 KLO16479.1 - 0.0031 17.5 0.1 0.011 15.7 0.0 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain BTB PF00651.26 KLO16480.1 - 0.003 17.5 0.0 0.0051 16.7 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain SRP9-21 PF05486.7 KLO16481.1 - 2.7e-13 49.4 0.5 1.1e-08 34.7 0.1 2.1 2 0 0 2 2 2 2 Signal recognition particle 9 kDa protein (SRP9) DUF2421 PF10334.4 KLO16482.1 - 0.07 12.7 0.0 0.097 12.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2421) Aldedh PF00171.17 KLO16487.1 - 7.2e-06 24.6 0.7 7.2e-06 24.6 0.5 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family FUSC_2 PF13515.1 KLO16488.1 - 0.00039 20.3 32.5 0.032 14.1 8.2 3.3 2 1 0 2 2 2 2 Fusaric acid resistance protein-like DUF2422 PF10337.4 KLO16488.1 - 0.0053 15.6 0.2 0.0053 15.6 0.2 3.5 2 1 1 3 3 3 2 Protein of unknown function (DUF2422) ALMT PF11744.3 KLO16488.1 - 0.0076 14.9 4.4 0.012 14.2 3.1 1.2 1 0 0 1 1 1 1 Aluminium activated malate transporter DUF2421 PF10334.4 KLO16488.1 - 0.15 11.6 0.3 0.77 9.3 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2421) UQ_con PF00179.21 KLO16490.1 - 6.6e-16 58.0 0.1 9.5e-16 57.4 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 KLO16490.1 - 0.031 14.1 0.0 0.039 13.8 0.0 1.3 1 0 0 1 1 1 0 RWD domain GST_C_3 PF14497.1 KLO16491.1 - 1.2e-11 44.9 0.2 3.4e-11 43.4 0.1 1.8 1 1 1 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 KLO16491.1 - 9.8e-10 38.3 0.2 1.9e-09 37.3 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 KLO16491.1 - 3.4e-05 23.6 0.0 6.6e-05 22.7 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 KLO16491.1 - 0.0029 17.7 0.0 0.013 15.6 0.0 2.2 2 1 0 2 2 2 1 Glutathione S-transferase, N-terminal domain HSP70 PF00012.15 KLO16492.1 - 0.13 10.1 0.0 0.62 7.8 0.0 2.0 2 1 0 2 2 2 0 Hsp70 protein MreB_Mbl PF06723.8 KLO16492.1 - 0.17 10.4 0.0 0.36 9.3 0.0 1.4 1 0 0 1 1 1 0 MreB/Mbl protein ALO PF04030.9 KLO16493.1 - 1.5e-79 267.3 0.4 1.9e-79 266.9 0.3 1.1 1 0 0 1 1 1 1 D-arabinono-1,4-lactone oxidase FAD_binding_4 PF01565.18 KLO16493.1 - 4.7e-28 97.3 0.0 7.4e-28 96.7 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain UPF0029 PF01205.14 KLO16493.1 - 0.032 13.9 0.0 0.059 13.0 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein family UPF0029 UQ_con PF00179.21 KLO16494.1 - 2.4e-44 150.1 0.0 2.8e-44 149.9 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Mito_carr PF00153.22 KLO16495.1 - 1.9e-63 210.1 1.4 1e-21 76.4 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein zf-MYND PF01753.13 KLO16497.1 - 1.5e-09 37.5 10.8 1.5e-09 37.5 7.5 2.1 3 1 0 3 3 3 1 MYND finger RAB3GAP2_N PF14655.1 KLO16497.1 - 0.021 13.8 0.0 0.033 13.2 0.0 1.3 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus Pox_Rap94 PF03294.9 KLO16497.1 - 0.19 9.6 0.9 0.23 9.3 0.6 1.1 1 0 0 1 1 1 0 RNA polymerase-associated transcription specificity factor, Rap94 Dus PF01207.12 KLO16498.1 - 3.9e-53 180.2 0.0 5.1e-53 179.9 0.0 1.0 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) DHDPS PF00701.17 KLO16498.1 - 0.075 11.6 0.0 0.12 11.0 0.0 1.2 1 0 0 1 1 1 0 Dihydrodipicolinate synthetase family DUF1628 PF07790.6 KLO16499.1 - 0.0049 17.6 4.1 0.011 16.5 2.8 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1628) DUF4366 PF14283.1 KLO16499.1 - 0.039 13.3 0.0 0.056 12.8 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) Gemini_mov PF01708.11 KLO16499.1 - 0.09 12.3 0.5 0.16 11.5 0.0 1.7 2 0 0 2 2 2 0 Geminivirus putative movement protein DUF3169 PF11368.3 KLO16499.1 - 0.95 8.6 3.8 0.38 9.9 0.7 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3169) Acetyltransf_3 PF13302.1 KLO16500.1 - 1.3e-16 61.0 0.1 2.3e-16 60.2 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 KLO16500.1 - 1.5e-07 31.3 0.0 2.4e-07 30.7 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_8 PF13523.1 KLO16500.1 - 9.6e-07 28.7 0.1 1.4e-06 28.2 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 KLO16500.1 - 4.4e-05 23.4 0.0 8.2e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 KLO16500.1 - 0.022 14.8 0.0 0.036 14.2 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain FR47 PF08445.5 KLO16500.1 - 0.069 12.9 0.0 0.13 12.0 0.0 1.3 1 0 0 1 1 1 0 FR47-like protein Acetyltransf_3 PF13302.1 KLO16501.1 - 2.4e-17 63.3 0.0 3e-17 63.1 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 KLO16501.1 - 2.2e-05 24.4 0.0 3.7e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_4 PF13420.1 KLO16501.1 - 0.0033 17.3 0.0 0.14 12.0 0.0 2.1 1 1 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 KLO16501.1 - 0.0046 16.8 0.8 0.25 11.2 0.0 2.9 2 1 0 3 3 3 1 Acetyltransferase (GNAT) domain Peptidase_A21 PF03566.8 KLO16502.1 - 0.048 11.7 4.9 0.053 11.6 2.7 1.5 1 1 0 1 1 1 0 Peptidase family A21 zf-MYND PF01753.13 KLO16503.1 - 8.3e-12 44.7 13.2 2.3e-11 43.3 9.2 1.8 1 0 0 1 1 1 1 MYND finger PolC_DP2 PF03833.8 KLO16503.1 - 0.001 16.8 1.1 0.0014 16.3 0.8 1.1 1 0 0 1 1 1 1 DNA polymerase II large subunit DP2 BioY PF02632.9 KLO16503.1 - 0.2 11.3 0.1 0.35 10.5 0.0 1.3 1 0 0 1 1 1 0 BioY family zf-MYND PF01753.13 KLO16504.1 - 5.3e-10 39.0 13.7 1.1e-09 37.9 9.5 1.6 1 0 0 1 1 1 1 MYND finger PolC_DP2 PF03833.8 KLO16504.1 - 0.0018 16.0 0.5 0.0025 15.5 0.3 1.1 1 0 0 1 1 1 1 DNA polymerase II large subunit DP2 Myb_DNA-binding PF00249.26 KLO16505.1 - 7.9e-15 54.6 0.0 8.2e-09 35.3 0.0 2.5 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 KLO16505.1 - 8.7e-13 48.1 1.7 1.4e-05 25.1 0.0 2.9 3 0 0 3 3 3 2 Myb-like DNA-binding domain SNF2_N PF00176.18 KLO16506.1 - 8.1e-46 156.1 0.0 1.9e-45 154.9 0.0 1.6 1 0 0 1 1 1 1 SNF2 family N-terminal domain zf-RING_2 PF13639.1 KLO16506.1 - 7.2e-08 32.1 11.8 1.4e-07 31.2 8.2 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 KLO16506.1 - 7.8e-07 28.6 10.0 1.5e-06 27.7 7.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KLO16506.1 - 2.2e-06 27.5 13.0 4.3e-06 26.6 9.0 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KLO16506.1 - 6.1e-06 25.8 12.0 1.3e-05 24.7 8.3 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KLO16506.1 - 2.3e-05 24.0 12.5 4.2e-05 23.1 8.7 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.2 KLO16506.1 - 0.002 18.2 5.4 0.0059 16.6 3.8 1.8 1 0 0 1 1 1 1 RING-H2 zinc finger Prok-RING_4 PF14447.1 KLO16506.1 - 0.016 14.7 6.5 0.051 13.1 4.5 1.8 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-Apc11 PF12861.2 KLO16506.1 - 0.14 12.0 4.1 0.35 10.7 2.6 1.9 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.1 KLO16506.1 - 0.23 11.1 5.5 0.3 10.8 2.9 2.0 1 1 0 1 1 1 0 RING-type zinc-finger zf-C3HC4_4 PF15227.1 KLO16506.1 - 1.8 8.5 11.2 3.9 7.4 7.8 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-Nse PF11789.3 KLO16506.1 - 3.7 7.1 7.1 12 5.5 4.5 2.1 2 0 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit MFS_1 PF07690.11 KLO16507.1 - 1.7e-21 76.3 46.1 6.7e-13 48.0 16.4 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 KLO16507.1 - 1.2e-20 73.5 21.1 2.5e-20 72.5 14.7 1.7 1 1 0 1 1 1 1 Sugar (and other) transporter Prefoldin PF02996.12 KLO16508.1 - 7.6e-28 96.5 2.2 5.3e-27 93.8 1.6 1.9 1 1 0 1 1 1 1 Prefoldin subunit Prefoldin_2 PF01920.15 KLO16508.1 - 0.00064 19.4 1.5 0.0071 16.1 0.1 2.2 2 0 0 2 2 2 1 Prefoldin subunit Syntaxin-6_N PF09177.6 KLO16508.1 - 0.062 13.7 1.1 5.4 7.4 0.2 2.5 2 1 0 2 2 2 0 Syntaxin 6, N-terminal FlaC_arch PF05377.6 KLO16508.1 - 0.2 11.5 1.3 2.9 7.8 0.1 2.8 2 1 0 2 2 2 0 Flagella accessory protein C (FlaC) RRM_1 PF00076.17 KLO16509.1 - 7.7e-56 185.6 0.0 8.2e-20 70.2 0.0 5.3 5 0 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KLO16509.1 - 4.9e-47 157.7 0.1 3.9e-14 52.3 0.0 4.6 4 0 0 4 4 4 4 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KLO16509.1 - 1.7e-24 85.4 0.0 4.1e-07 29.7 0.0 4.3 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 KLO16509.1 - 0.00071 19.3 0.0 0.25 11.2 0.0 3.9 4 0 0 4 4 4 1 RNA binding motif RRM_2 PF04059.7 KLO16509.1 - 0.011 15.7 0.0 5.9 6.9 0.0 3.4 4 0 0 4 4 4 0 RNA recognition motif 2 Nup35_RRM_2 PF14605.1 KLO16509.1 - 0.037 13.8 0.0 0.57 9.9 0.0 2.6 3 0 0 3 3 3 0 Nup53/35/40-type RNA recognition motif zf-MYND PF01753.13 KLO16510.1 - 7.8e-10 38.4 13.0 1.4e-09 37.6 9.0 1.4 1 0 0 1 1 1 1 MYND finger PolC_DP2 PF03833.8 KLO16510.1 - 0.54 7.8 1.8 0.77 7.3 1.2 1.1 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 zf-Mss51 PF13824.1 KLO16510.1 - 1.7 8.5 5.6 4.7 7.1 3.9 1.8 1 0 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 PCI PF01399.22 KLO16511.1 - 1.7e-09 37.9 0.0 3.8e-09 36.7 0.0 1.6 1 0 0 1 1 1 1 PCI domain Hist_deacetyl PF00850.14 KLO16512.1 - 4.8e-59 200.1 0.0 6.3e-59 199.7 0.0 1.1 1 0 0 1 1 1 1 Histone deacetylase domain Cyclase_polyket PF04673.7 KLO16512.1 - 0.073 13.1 0.0 0.15 12.1 0.0 1.4 1 0 0 1 1 1 0 Polyketide synthesis cyclase BTB PF00651.26 KLO16513.1 - 0.0016 18.4 0.1 0.026 14.5 0.1 2.8 2 1 0 2 2 2 1 BTB/POZ domain MFS_1 PF07690.11 KLO16514.1 - 7.3e-39 133.4 44.5 2.1e-38 131.9 30.8 1.8 1 1 0 1 1 1 1 Major Facilitator Superfamily MFS_1 PF07690.11 KLO16515.1 - 7.3e-41 140.0 51.0 3.8e-39 134.3 33.8 2.9 2 1 0 2 2 2 2 Major Facilitator Superfamily UNC-93 PF05978.11 KLO16515.1 - 1.4 8.3 17.4 0.65 9.4 0.8 3.8 3 2 1 4 4 4 0 Ion channel regulatory protein UNC-93 PIRT PF15099.1 KLO16515.1 - 1.6 7.9 4.8 9.9 5.3 0.0 3.0 3 0 0 3 3 3 0 Phosphoinositide-interacting protein family STE3 PF02076.10 KLO16516.1 - 2e-98 328.9 17.2 2.4e-98 328.7 11.9 1.0 1 0 0 1 1 1 1 Pheromone A receptor Pheromone PF08015.6 KLO16517.1 - 2.9e-08 34.4 1.0 4.7e-08 33.7 0.7 1.3 1 1 0 1 1 1 1 Fungal mating-type pheromone STE3 PF02076.10 KLO16518.1 - 3.9e-89 298.4 19.8 4.7e-89 298.2 13.7 1.0 1 0 0 1 1 1 1 Pheromone A receptor DUF605 PF04652.11 KLO16518.1 - 6.5 6.0 9.1 8.6 5.6 6.3 1.1 1 0 0 1 1 1 0 Vta1 like DUF4255 PF14065.1 KLO16519.1 - 0.043 13.2 0.2 0.075 12.4 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF4255) STE3 PF02076.10 KLO16520.1 - 1.9e-99 332.3 15.7 2.2e-99 332.0 10.9 1.0 1 0 0 1 1 1 1 Pheromone A receptor STE3 PF02076.10 KLO16521.1 - 1.7e-43 148.7 7.2 2.3e-43 148.2 5.0 1.1 1 0 0 1 1 1 1 Pheromone A receptor DUF2363 PF10155.4 KLO16523.1 - 8.9e-05 22.4 0.0 0.00056 19.8 0.0 2.2 3 0 0 3 3 3 1 Uncharacterized conserved protein (DUF2363) Pkinase PF00069.20 KLO16524.1 - 7.5e-70 235.0 0.3 1.4e-69 234.1 0.1 1.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 KLO16524.1 - 6.5e-52 176.1 0.3 4.8e-51 173.3 0.1 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase PBD PF00786.23 KLO16524.1 - 3.1e-22 78.7 0.0 1.1e-21 77.0 0.0 2.0 1 0 0 1 1 1 1 P21-Rho-binding domain Kinase-like PF14531.1 KLO16524.1 - 1.5e-06 27.3 0.0 2.6e-06 26.6 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 KLO16524.1 - 0.0068 16.1 0.2 0.0068 16.1 0.1 2.2 2 1 1 3 3 3 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 KLO16524.1 - 0.038 12.8 0.1 0.078 11.8 0.1 1.4 1 0 0 1 1 1 0 Seadornavirus VP7 Fork_head_N PF08430.7 KLO16524.1 - 1.1 9.6 28.9 0.28 11.5 10.4 2.5 2 0 0 2 2 2 0 Forkhead N-terminal region Ribosomal_S19 PF00203.16 KLO16525.1 - 1.3e-22 79.1 0.0 1.7e-22 78.8 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S19 Misat_Tub_SegII PF10644.4 KLO16527.1 - 2.4e-36 124.3 0.0 4.5e-36 123.4 0.0 1.5 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.1 KLO16527.1 - 6.4e-30 103.9 0.0 1.2e-29 103.0 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain Tubulin PF00091.20 KLO16527.1 - 3.4e-08 33.5 0.0 0.0034 17.2 0.0 2.3 2 0 0 2 2 2 2 Tubulin/FtsZ family, GTPase domain zf-MYND PF01753.13 KLO16528.1 - 1.6e-08 34.2 14.1 3.3e-08 33.2 9.8 1.6 1 0 0 1 1 1 1 MYND finger F-box-like PF12937.2 KLO16530.1 - 0.00015 21.4 0.0 0.00031 20.3 0.0 1.5 1 0 0 1 1 1 1 F-box-like zf-MYND PF01753.13 KLO16531.1 - 1.4e-07 31.2 18.3 2.9e-07 30.2 12.7 1.6 1 0 0 1 1 1 1 MYND finger PolC_DP2 PF03833.8 KLO16531.1 - 0.28 8.7 1.1 0.43 8.1 0.8 1.2 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 OTU PF02338.14 KLO16532.1 - 1.1e-13 51.8 0.1 2.3e-13 50.7 0.0 1.6 2 0 0 2 2 2 1 OTU-like cysteine protease Peptidase_C65 PF10275.4 KLO16532.1 - 0.0044 16.4 0.0 0.43 9.8 0.0 2.2 2 0 0 2 2 2 2 Peptidase C65 Otubain Tim54 PF11711.3 KLO16532.1 - 0.021 13.4 1.0 0.034 12.7 0.7 1.3 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 FAM176 PF14851.1 KLO16532.1 - 1.2 8.7 7.7 0.48 10.0 1.7 2.2 2 0 0 2 2 2 0 FAM176 family AAA_11 PF13086.1 KLO16533.1 - 2.6e-54 184.3 0.3 3.9e-54 183.7 0.2 1.3 1 0 0 1 1 1 1 AAA domain AAA_12 PF13087.1 KLO16533.1 - 2.7e-54 183.5 0.0 6.2e-54 182.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 KLO16533.1 - 5.3e-11 42.1 0.0 3.6e-10 39.4 0.0 2.2 2 0 0 2 2 2 1 Part of AAA domain AAA_30 PF13604.1 KLO16533.1 - 1.8e-10 40.6 0.0 6.6e-06 25.8 0.0 2.6 1 1 0 2 2 2 2 AAA domain Viral_helicase1 PF01443.13 KLO16533.1 - 6e-06 25.9 0.1 1.1 8.6 0.0 3.4 3 0 0 3 3 3 3 Viral (Superfamily 1) RNA helicase UvrD-helicase PF00580.16 KLO16533.1 - 8.5e-06 25.2 3.9 5.7e-05 22.5 2.7 2.3 1 1 0 1 1 1 1 UvrD/REP helicase N-terminal domain DUF342 PF03961.8 KLO16533.1 - 0.00075 18.0 2.2 0.0012 17.3 1.5 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF342) ResIII PF04851.10 KLO16533.1 - 0.0017 18.1 0.2 0.0053 16.6 0.1 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Arch_ATPase PF01637.13 KLO16533.1 - 0.0027 17.4 0.6 0.011 15.4 0.1 2.2 1 1 1 2 2 2 1 Archaeal ATPase AAA PF00004.24 KLO16533.1 - 0.02 15.0 0.3 0.22 11.7 0.4 2.7 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) DUF1664 PF07889.7 KLO16533.1 - 0.025 14.3 0.6 0.051 13.3 0.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Phage_GP20 PF06810.6 KLO16533.1 - 0.056 12.8 2.9 0.11 11.9 2.0 1.4 1 0 0 1 1 1 0 Phage minor structural protein GP20 AAA_16 PF13191.1 KLO16533.1 - 0.076 12.9 0.1 0.33 10.9 0.0 2.2 1 1 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.1 KLO16533.1 - 0.085 12.9 0.0 0.56 10.3 0.0 2.3 2 0 0 2 2 2 0 AAA domain TBPIP PF07106.8 KLO16533.1 - 0.19 11.2 7.6 0.077 12.5 3.3 1.8 2 0 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) AAA_18 PF13238.1 KLO16533.1 - 0.23 11.7 2.5 0.87 9.9 0.2 3.0 3 1 0 3 3 3 0 AAA domain OmpH PF03938.9 KLO16533.1 - 0.26 11.2 4.8 0.12 12.2 1.5 1.7 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) IncA PF04156.9 KLO16533.1 - 0.65 9.5 5.1 1.5 8.3 3.5 1.5 1 0 0 1 1 1 0 IncA protein TMPIT PF07851.8 KLO16533.1 - 1.9 7.4 4.1 3.1 6.7 2.9 1.2 1 0 0 1 1 1 0 TMPIT-like protein Atg14 PF10186.4 KLO16533.1 - 2 7.2 9.5 0.7 8.7 4.2 1.8 2 0 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 MFS_1 PF07690.11 KLO16534.1 - 6.2e-22 77.7 44.3 6.2e-22 77.7 30.7 2.4 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KLO16534.1 - 6.7e-05 21.6 37.4 0.0026 16.4 9.0 3.0 2 1 1 3 3 3 2 Sugar (and other) transporter MFS_1_like PF12832.2 KLO16534.1 - 0.14 11.9 4.6 0.95 9.3 0.8 2.8 2 0 0 2 2 2 0 MFS_1 like family HD PF01966.17 KLO16541.1 - 1.4e-05 25.0 0.0 2.2e-05 24.4 0.0 1.2 1 0 0 1 1 1 1 HD domain 60KD_IMP PF02096.15 KLO16542.1 - 2.1e-29 102.6 0.5 3.4e-29 101.9 0.4 1.3 1 0 0 1 1 1 1 60Kd inner membrane protein Sugar_tr PF00083.19 KLO16543.1 - 5.5e-108 361.4 29.5 6.5e-108 361.2 20.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KLO16543.1 - 4.8e-28 97.8 25.5 4.8e-28 97.8 17.7 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 KLO16543.1 - 1.1e-07 30.4 3.2 1.1e-07 30.4 2.2 1.9 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) AbrB-like PF14250.1 KLO16543.1 - 0.13 12.1 0.0 0.64 9.9 0.0 2.2 2 0 0 2 2 2 0 AbrB-like transcriptional regulator Nop53 PF07767.6 KLO16544.1 - 4.6e-66 223.3 20.8 5.4e-66 223.1 14.4 1.0 1 0 0 1 1 1 1 Nop53 (60S ribosomal biogenesis) RR_TM4-6 PF06459.7 KLO16544.1 - 5 6.9 16.4 5.9 6.7 10.3 1.8 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 Phage_holin_5 PF06946.6 KLO16546.1 - 0.083 13.0 0.6 3.1 8.0 0.0 2.9 2 1 1 3 3 3 0 Phage holin PDZ_1 PF12812.2 KLO16547.1 - 0.1 12.5 0.0 0.15 11.9 0.0 1.3 1 0 0 1 1 1 0 PDZ-like domain F-box-like PF12937.2 KLO16548.1 - 1.7e-05 24.4 0.1 8.1e-05 22.2 0.0 2.3 1 0 0 1 1 1 1 F-box-like RHS_repeat PF05593.9 KLO16551.1 - 3.4e-18 65.3 46.1 0.00037 20.5 0.5 13.7 10 3 4 14 14 14 7 RHS Repeat VCBS PF13517.1 KLO16551.1 - 1.3e-08 35.0 11.7 2e-05 24.8 0.6 5.2 3 0 0 3 3 3 2 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella TcdB_toxin_midN PF12256.3 KLO16551.1 - 5.4e-08 32.4 33.0 0.00014 21.3 0.0 8.6 9 1 0 10 10 10 2 Insecticide toxin TcdB middle/N-terminal region SpvB PF03534.8 KLO16551.1 - 1.1e-06 27.8 6.8 1.8e-05 23.9 0.2 3.3 2 1 1 3 3 3 2 Salmonella virulence plasmid 65kDa B protein FG-GAP PF01839.18 KLO16551.1 - 0.0012 18.4 3.4 0.33 10.6 0.2 3.3 2 0 0 2 2 2 2 FG-GAP repeat FA_desaturase PF00487.19 KLO16551.1 - 0.13 11.6 0.1 0.25 10.7 0.1 1.3 1 0 0 1 1 1 0 Fatty acid desaturase IncA PF04156.9 KLO16551.1 - 5.6 6.5 3.4 10 5.6 2.4 1.3 1 0 0 1 1 1 0 IncA protein zf-MYND PF01753.13 KLO16552.1 - 0.00047 19.9 12.6 0.00047 19.9 8.7 2.8 3 0 0 3 3 3 1 MYND finger F-box-like PF12937.2 KLO16552.1 - 0.0017 18.0 1.4 0.0074 15.9 1.0 2.1 1 0 0 1 1 1 1 F-box-like Pro_CA PF00484.14 KLO16553.1 - 1.9e-07 31.1 0.0 1.9e-07 31.1 0.0 1.0 1 0 0 1 1 1 1 Carbonic anhydrase Pro_CA PF00484.14 KLO16554.1 - 1.2e-07 31.8 0.3 4e-07 30.1 0.0 1.8 2 0 0 2 2 2 1 Carbonic anhydrase F-box-like PF12937.2 KLO16555.1 - 0.00014 21.5 0.8 0.00029 20.4 0.1 2.0 2 0 0 2 2 2 1 F-box-like F-box-like PF12937.2 KLO16556.1 - 4.6e-05 23.0 0.3 0.00033 20.3 0.0 2.4 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 KLO16556.1 - 0.039 13.6 0.3 0.32 10.7 0.0 2.5 2 0 0 2 2 2 0 F-box domain LRR_6 PF13516.1 KLO16556.1 - 0.11 12.6 1.5 11 6.4 0.0 3.8 3 0 0 3 3 3 0 Leucine Rich repeat F-box-like PF12937.2 KLO16557.1 - 1.8e-05 24.3 0.9 6.1e-05 22.6 0.0 2.3 2 0 0 2 2 2 1 F-box-like BSP_II PF05432.6 KLO16557.1 - 0.12 11.6 5.9 0.18 11.0 4.1 1.1 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) F-box-like PF12937.2 KLO16558.1 - 3.2e-06 26.7 0.1 7.6e-06 25.5 0.1 1.6 1 0 0 1 1 1 1 F-box-like RBD PF02196.10 KLO16558.1 - 0.11 12.2 0.1 8.9 6.1 0.0 3.2 3 0 0 3 3 3 0 Raf-like Ras-binding domain zf-C2H2_jaz PF12171.3 KLO16559.1 - 0.018 15.1 0.0 0.033 14.3 0.0 1.4 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.1 KLO16559.1 - 0.018 15.3 0.1 0.057 13.7 0.1 1.8 1 0 0 1 1 1 0 C2H2-type zinc finger BIR PF00653.16 KLO16559.1 - 0.057 13.8 0.9 0.14 12.6 0.6 1.6 1 0 0 1 1 1 0 Inhibitor of Apoptosis domain zf-ISL3 PF14690.1 KLO16559.1 - 0.17 11.9 1.6 0.49 10.4 1.1 1.8 1 0 0 1 1 1 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 EHN PF06441.7 KLO16560.1 - 2.1e-34 117.8 0.4 6.3e-34 116.2 0.0 1.9 2 0 0 2 2 2 1 Epoxide hydrolase N terminus Abhydrolase_6 PF12697.2 KLO16560.1 - 2.9e-10 40.4 0.1 8.9e-10 38.8 0.1 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KLO16560.1 - 0.00038 20.0 0.0 0.00064 19.3 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Ras PF00071.17 KLO16561.1 - 2.4e-49 166.8 0.0 2.9e-49 166.5 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KLO16561.1 - 4.4e-20 72.3 0.0 5.8e-20 71.9 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KLO16561.1 - 1.1e-07 31.2 0.0 1.9e-07 30.5 0.0 1.3 1 1 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 KLO16561.1 - 0.006 15.8 0.0 0.0092 15.2 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.7 KLO16561.1 - 0.056 12.5 0.0 0.069 12.2 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 KLO16561.1 - 0.095 12.6 0.0 0.15 12.0 0.0 1.3 1 0 0 1 1 1 0 50S ribosome-binding GTPase Aldedh PF00171.17 KLO16563.1 - 8e-180 598.0 0.2 9e-180 597.9 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 KLO16563.1 - 0.00019 20.2 0.0 0.00029 19.6 0.0 1.2 1 0 0 1 1 1 1 Acyl-CoA reductase (LuxC) DUF1487 PF07368.6 KLO16563.1 - 0.007 15.6 0.0 0.85 8.8 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF1487) F-box-like PF12937.2 KLO16564.1 - 5.6e-06 25.9 1.3 5.6e-06 25.9 0.9 3.2 4 1 0 4 4 4 1 F-box-like F-box PF00646.28 KLO16564.1 - 0.19 11.4 1.9 8.4 6.1 0.1 3.6 3 1 0 3 3 3 0 F-box domain TauD PF02668.11 KLO16565.1 - 7.4e-45 153.6 0.2 8.5e-45 153.4 0.1 1.0 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family 2OG-FeII_Oxy_3 PF13640.1 KLO16565.1 - 7.5e-05 23.1 0.1 0.23 12.0 0.0 2.5 2 0 0 2 2 2 2 2OG-Fe(II) oxygenase superfamily Sugar_tr PF00083.19 KLO16566.1 - 1.5e-86 290.7 29.3 1.7e-86 290.6 20.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KLO16566.1 - 2.7e-25 88.8 30.5 2.7e-25 88.8 21.1 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily MFS_2 PF13347.1 KLO16566.1 - 0.0001 20.8 35.8 0.00095 17.6 2.5 4.1 2 2 2 4 4 4 3 MFS/sugar transport protein Sugar_tr PF00083.19 KLO16567.1 - 1.4e-84 284.3 21.3 1.6e-84 284.0 14.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KLO16567.1 - 1.2e-21 76.8 52.7 1.9e-20 72.9 18.5 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Lyase_1 PF00206.15 KLO16568.1 - 7.3e-23 81.2 0.0 1.2e-22 80.5 0.0 1.2 1 0 0 1 1 1 1 Lyase ADSL_C PF10397.4 KLO16568.1 - 2.1e-17 62.9 0.0 5e-17 61.6 0.0 1.7 1 0 0 1 1 1 1 Adenylosuccinate lyase C-terminus Pkinase PF00069.20 KLO16569.1 - 7.4e-69 231.7 0.0 1.2e-68 231.0 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KLO16569.1 - 1.5e-37 129.0 0.0 2.7e-37 128.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KLO16569.1 - 8e-06 25.0 0.0 1.4e-05 24.2 0.0 1.2 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.17 KLO16569.1 - 0.014 14.7 0.1 0.033 13.5 0.1 1.5 1 0 0 1 1 1 0 RIO1 family zf-H2C2 PF09337.5 KLO16570.1 - 0.018 14.4 0.8 0.03 13.7 0.6 1.4 1 0 0 1 1 1 0 His(2)-Cys(2) zinc finger SUI1 PF01253.17 KLO16572.1 - 8.9e-13 47.8 0.0 1.8e-12 46.8 0.0 1.4 1 0 0 1 1 1 1 Translation initiation factor SUI1 PUA PF01472.15 KLO16572.1 - 7.6e-05 22.3 0.0 0.00016 21.3 0.0 1.5 1 0 0 1 1 1 1 PUA domain Kin17_mid PF10357.4 KLO16572.1 - 0.096 12.3 1.2 0.19 11.3 0.8 1.4 1 0 0 1 1 1 0 Domain of Kin17 curved DNA-binding protein zf-C2H2_4 PF13894.1 KLO16573.1 - 9.5e-07 28.7 35.9 0.00079 19.5 2.0 5.4 5 0 0 5 5 5 4 C2H2-type zinc finger zf-C2HC_2 PF13913.1 KLO16573.1 - 0.00027 20.5 5.5 0.024 14.2 0.0 3.6 3 0 0 3 3 3 2 zinc-finger of a C2HC-type zf-C2H2 PF00096.21 KLO16573.1 - 0.0039 17.4 36.4 0.043 14.1 1.1 5.9 6 1 0 6 6 6 4 Zinc finger, C2H2 type zf-C2H2_6 PF13912.1 KLO16573.1 - 0.01 15.7 21.8 0.63 10.0 0.9 4.7 4 0 0 4 4 4 0 C2H2-type zinc finger zf-met PF12874.2 KLO16573.1 - 0.012 15.7 17.1 1.1 9.5 1.5 4.6 4 0 0 4 4 3 0 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 KLO16573.1 - 0.038 14.1 4.2 0.038 14.1 2.9 6.5 5 2 1 6 6 6 0 Zinc-finger double-stranded RNA-binding DUF3398 PF11878.3 KLO16573.1 - 0.13 12.0 1.2 3.5 7.5 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3398) Ecl1 PF12855.2 KLO16573.1 - 0.17 11.2 9.2 0.19 11.0 0.4 3.3 3 0 0 3 3 3 0 Life-span regulatory factor DZR PF12773.2 KLO16573.1 - 0.17 11.7 9.7 3e+02 1.3 6.7 3.2 1 1 0 1 1 1 0 Double zinc ribbon DUF2318 PF10080.4 KLO16573.1 - 1.2 8.9 5.5 2.3 8.0 0.1 3.2 3 1 1 4 4 4 0 Predicted membrane protein (DUF2318) zf-H2C2_5 PF13909.1 KLO16573.1 - 1.4 9.3 32.3 0.59 10.4 2.2 5.7 6 0 0 6 6 5 0 C2H2-type zinc-finger domain PyrI_C PF02748.10 KLO16573.1 - 3.5 7.1 14.5 0.085 12.2 0.9 3.6 3 1 1 4 4 4 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain Yippee-Mis18 PF03226.9 KLO16573.1 - 4.5 7.3 9.1 0.35 10.9 0.7 2.5 2 1 1 3 3 3 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly HypA PF01155.14 KLO16573.1 - 6.8 6.4 8.7 4 7.1 0.3 2.9 1 1 1 3 3 3 0 Hydrogenase expression/synthesis hypA family HMG_box PF00505.14 KLO16574.1 - 2.4e-22 78.9 0.4 4e-22 78.2 0.3 1.4 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 KLO16574.1 - 1.2e-18 67.2 1.2 2.2e-18 66.4 0.9 1.4 1 0 0 1 1 1 1 HMG-box domain CHDNT PF08073.7 KLO16574.1 - 0.0041 16.7 0.0 0.0075 15.9 0.0 1.4 1 0 0 1 1 1 1 CHDNT (NUC034) domain HMG_box_5 PF14887.1 KLO16574.1 - 0.029 14.1 0.0 0.061 13.1 0.0 1.5 1 0 0 1 1 1 0 HMG (high mobility group) box 5 TOM20_plant PF06552.7 KLO16574.1 - 0.076 12.5 0.1 0.12 11.9 0.1 1.2 1 0 0 1 1 1 0 Plant specific mitochondrial import receptor subunit TOM20 zf-C2H2 PF00096.21 KLO16575.1 - 0.089 13.1 32.9 1.9 8.9 0.2 5.7 4 2 2 6 6 6 0 Zinc finger, C2H2 type zf-met PF12874.2 KLO16575.1 - 0.84 9.9 18.8 3.7 7.9 2.3 5.3 6 0 0 6 6 6 0 Zinc-finger of C2H2 type Sgf11 PF08209.6 KLO16575.1 - 1.3 8.3 9.7 2.4 7.5 0.5 3.2 3 0 0 3 3 3 0 Sgf11 (transcriptional regulation protein) C1_3 PF07649.7 KLO16575.1 - 1.8 8.6 16.7 11 6.1 0.0 4.1 4 0 0 4 4 4 0 C1-like domain zf-P11 PF03854.9 KLO16575.1 - 2.1 7.8 0.0 2.1 7.8 0.0 3.9 5 0 0 5 5 5 0 P-11 zinc finger DZR PF12773.2 KLO16575.1 - 2.9 7.7 9.8 5.7e+02 0.4 6.8 3.3 1 1 0 1 1 1 0 Double zinc ribbon Prim_Zn_Ribbon PF08273.7 KLO16575.1 - 4.4 7.4 7.2 4.6 7.3 0.1 3.1 3 0 0 3 3 3 0 Zinc-binding domain of primase-helicase DUF4182 PF13790.1 KLO16575.1 - 7.8 6.3 8.3 17 5.2 0.1 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4182) zf-C2H2 PF00096.21 KLO16576.1 - 3.3e-15 55.3 48.0 0.0035 17.6 1.3 9.5 8 1 1 9 9 9 7 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KLO16576.1 - 5.9e-09 35.6 50.5 0.1 12.9 0.8 9.6 8 1 1 9 9 9 5 C2H2-type zinc finger zf-C2H2_6 PF13912.1 KLO16576.1 - 6.1e-09 35.4 42.1 0.014 15.2 0.2 8.7 8 0 0 8 8 8 5 C2H2-type zinc finger zf-met PF12874.2 KLO16576.1 - 3.1e-08 33.5 37.3 0.00013 22.0 1.8 8.4 10 0 0 10 10 9 2 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 KLO16576.1 - 2.5e-07 30.6 62.9 0.00028 20.9 3.7 8.9 9 1 0 9 9 9 5 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.2 KLO16576.1 - 0.00033 20.7 36.4 0.09 12.8 9.3 4.9 2 1 3 5 5 5 3 C2H2 type zinc-finger (2 copies) zf-trcl PF13451.1 KLO16576.1 - 0.012 15.2 2.7 0.012 15.2 1.9 4.3 7 1 0 7 7 7 0 Probable zinc-binding domain zf-H2C2_2 PF13465.1 KLO16576.1 - 0.053 13.8 0.2 0.29 11.5 0.1 8.8 9 1 0 9 9 8 0 Zinc-finger double domain TMEM210 PF15195.1 KLO16576.1 - 0.083 13.0 0.0 0.16 12.1 0.0 1.4 1 0 0 1 1 1 0 TMEM210 family ABM PF03992.11 KLO16576.1 - 0.22 11.5 2.5 13 5.9 0.5 2.9 2 0 0 2 2 2 0 Antibiotic biosynthesis monooxygenase DUF2318 PF10080.4 KLO16576.1 - 1.8 8.3 13.1 19 5.1 0.3 5.3 4 1 2 6 6 6 0 Predicted membrane protein (DUF2318) zf-C2HC_2 PF13913.1 KLO16576.1 - 5.1 6.8 15.4 16 5.2 0.1 5.6 5 0 0 5 5 5 0 zinc-finger of a C2HC-type Oxysterol_BP PF01237.13 KLO16577.1 - 8.5e-76 254.7 0.0 1.1e-75 254.3 0.0 1.1 1 0 0 1 1 1 1 Oxysterol-binding protein PACT_coil_coil PF10495.4 KLO16577.1 - 0.087 12.7 0.0 0.2 11.6 0.0 1.5 1 0 0 1 1 1 0 Pericentrin-AKAP-450 domain of centrosomal targeting protein TGF_beta_GS PF08515.7 KLO16578.1 - 0.2 11.0 2.4 0.33 10.3 0.1 2.4 2 0 0 2 2 2 0 Transforming growth factor beta type I GS-motif Pro_CA PF00484.14 KLO16579.1 - 3.4e-33 114.8 0.6 4.6e-33 114.3 0.4 1.2 1 0 0 1 1 1 1 Carbonic anhydrase Pro_CA PF00484.14 KLO16580.1 - 4.3e-32 111.2 0.3 8.7e-32 110.2 0.2 1.5 1 1 0 1 1 1 1 Carbonic anhydrase Aminotran_4 PF01063.14 KLO16581.1 - 2.5e-31 108.9 0.0 3.3e-31 108.5 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class IV Mito_carr PF00153.22 KLO16582.1 - 3.6e-68 225.3 2.9 4.3e-22 77.6 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Tim17 PF02466.14 KLO16582.1 - 0.045 13.7 5.7 14 5.7 0.0 3.8 2 2 1 3 3 3 0 Tim17/Tim22/Tim23/Pmp24 family V4R PF02830.13 KLO16582.1 - 0.17 11.7 1.1 0.42 10.4 0.0 2.3 2 0 0 2 2 2 0 V4R domain Pyr_redox_3 PF13738.1 KLO16583.1 - 9.3e-27 94.4 0.0 1.2e-25 90.8 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 KLO16583.1 - 5e-24 84.3 0.0 2.6e-20 72.1 0.0 2.4 2 1 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.9 KLO16583.1 - 4.8e-13 49.4 0.0 9.7e-11 41.9 0.0 2.2 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 KLO16583.1 - 3.1e-12 46.0 0.0 6.5e-08 31.8 0.0 3.1 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.1 KLO16583.1 - 1.8e-06 27.8 0.1 0.01 15.6 0.0 2.4 2 0 0 2 2 2 2 FAD-NAD(P)-binding Shikimate_DH PF01488.15 KLO16583.1 - 8.1e-06 25.9 0.1 0.035 14.1 0.0 2.4 2 0 0 2 2 2 2 Shikimate / quinate 5-dehydrogenase Pyr_redox PF00070.22 KLO16583.1 - 9.9e-06 25.8 0.4 0.025 14.9 0.0 2.8 3 0 0 3 3 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 KLO16583.1 - 9.7e-05 21.4 0.0 0.02 13.7 0.0 2.9 2 1 1 3 3 3 1 FAD dependent oxidoreductase TrkA_N PF02254.13 KLO16583.1 - 0.0017 18.3 0.1 0.017 15.0 0.0 2.2 2 0 0 2 2 2 1 TrkA-N domain NAD_binding_7 PF13241.1 KLO16583.1 - 0.0018 18.4 0.0 1.5 9.1 0.0 2.4 2 0 0 2 2 2 2 Putative NAD(P)-binding HI0933_like PF03486.9 KLO16583.1 - 0.0026 16.2 0.1 0.013 13.9 0.0 2.0 2 0 0 2 2 2 1 HI0933-like protein CPSase_L_chain PF00289.17 KLO16583.1 - 0.0027 17.7 0.3 0.093 12.8 0.0 2.3 2 0 0 2 2 2 1 Carbamoyl-phosphate synthase L chain, N-terminal domain Lycopene_cycl PF05834.7 KLO16583.1 - 0.0034 16.3 0.1 0.027 13.3 0.0 2.3 3 0 0 3 3 3 1 Lycopene cyclase protein NAD_binding_8 PF13450.1 KLO16583.1 - 0.0035 17.3 0.0 0.009 16.0 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain 2-Hacid_dh_C PF02826.14 KLO16583.1 - 0.0058 15.8 0.0 0.16 11.0 0.0 2.4 3 0 0 3 3 3 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain GIDA PF01134.17 KLO16583.1 - 0.0067 15.3 0.0 1.5 7.5 0.0 2.2 2 0 0 2 2 2 2 Glucose inhibited division protein A Thi4 PF01946.12 KLO16583.1 - 0.015 14.3 0.0 0.045 12.8 0.0 1.7 1 0 0 1 1 1 0 Thi4 family FAD_binding_2 PF00890.19 KLO16583.1 - 0.029 13.2 0.0 0.091 11.5 0.0 1.8 2 0 0 2 2 2 0 FAD binding domain FAD_binding_3 PF01494.14 KLO16583.1 - 0.032 13.2 0.0 0.056 12.4 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain Fungal_lectin PF07938.7 KLO16583.1 - 0.066 12.4 0.0 0.13 11.5 0.0 1.3 1 0 0 1 1 1 0 Fungal fucose-specific lectin FMO-like PF00743.14 KLO16584.1 - 1.1e-25 89.9 0.0 1.4e-20 73.0 0.0 2.3 2 1 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 KLO16584.1 - 1.6e-25 90.3 0.0 2.9e-24 86.2 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 KLO16584.1 - 6.5e-12 45.7 0.0 3.1e-09 37.0 0.0 2.1 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 KLO16584.1 - 1.1e-11 44.2 0.0 8.7e-08 31.4 0.0 3.1 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.1 KLO16584.1 - 2.3e-06 27.4 0.1 0.021 14.6 0.0 2.4 2 0 0 2 2 2 2 FAD-NAD(P)-binding Shikimate_DH PF01488.15 KLO16584.1 - 9.9e-05 22.4 1.0 0.61 10.1 0.0 2.7 3 0 0 3 3 2 2 Shikimate / quinate 5-dehydrogenase DAO PF01266.19 KLO16584.1 - 0.00022 20.2 0.0 0.06 12.2 0.0 2.6 2 0 0 2 2 2 2 FAD dependent oxidoreductase HI0933_like PF03486.9 KLO16584.1 - 0.0015 17.0 0.1 0.034 12.6 0.0 2.2 2 0 0 2 2 2 1 HI0933-like protein NAD_binding_8 PF13450.1 KLO16584.1 - 0.0037 17.2 0.0 0.011 15.6 0.0 1.9 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 KLO16584.1 - 0.0043 17.4 0.2 0.18 12.1 0.0 2.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.13 KLO16584.1 - 0.0046 16.9 0.0 0.016 15.1 0.0 1.9 2 0 0 2 2 2 1 TrkA-N domain SnoaL_2 PF12680.2 KLO16584.1 - 0.0053 17.1 0.0 0.021 15.2 0.0 2.0 1 0 0 1 1 1 1 SnoaL-like domain Lycopene_cycl PF05834.7 KLO16584.1 - 0.019 13.9 0.0 0.15 10.9 0.0 2.1 2 0 0 2 2 2 0 Lycopene cyclase protein GIDA PF01134.17 KLO16584.1 - 0.036 12.9 0.1 1.4 7.7 0.0 2.2 2 0 0 2 2 2 0 Glucose inhibited division protein A FAD_binding_2 PF00890.19 KLO16584.1 - 0.09 11.6 0.0 0.21 10.4 0.0 1.6 1 0 0 1 1 1 0 FAD binding domain FAD_binding_3 PF01494.14 KLO16584.1 - 0.15 11.1 0.0 0.4 9.6 0.0 1.7 2 0 0 2 2 2 0 FAD binding domain NAD_binding_7 PF13241.1 KLO16584.1 - 0.15 12.3 0.0 3.9 7.7 0.0 2.3 2 0 0 2 2 2 0 Putative NAD(P)-binding CPSase_L_chain PF00289.17 KLO16584.1 - 0.28 11.2 0.9 2 8.5 0.0 2.6 3 0 0 3 3 3 0 Carbamoyl-phosphate synthase L chain, N-terminal domain Kelch_4 PF13418.1 KLO16585.1 - 5.2e-51 170.2 12.2 2e-09 37.0 0.2 6.3 6 0 0 6 6 6 6 Galactose oxidase, central domain Kelch_3 PF13415.1 KLO16585.1 - 1.3e-41 139.8 22.9 1.7e-09 37.6 0.0 7.8 8 0 0 8 8 8 6 Galactose oxidase, central domain Kelch_1 PF01344.20 KLO16585.1 - 6.1e-38 128.1 3.6 4.7e-07 29.2 0.0 6.2 6 0 0 6 6 6 6 Kelch motif Kelch_5 PF13854.1 KLO16585.1 - 3.5e-35 119.3 8.7 3.5e-06 26.8 0.0 6.2 6 0 0 6 6 6 6 Kelch motif Kelch_6 PF13964.1 KLO16585.1 - 2e-34 116.3 7.6 7e-08 32.3 0.1 6.3 5 1 1 6 6 6 6 Kelch motif Kelch_2 PF07646.10 KLO16585.1 - 2.1e-24 84.3 7.8 0.00087 18.9 0.0 6.3 6 0 0 6 6 6 6 Kelch motif PQQ_3 PF13570.1 KLO16585.1 - 0.00047 20.3 4.0 11 6.4 0.0 5.7 6 0 0 6 6 6 1 PQQ-like domain Cornifin PF02389.10 KLO16586.1 - 0.0033 17.2 4.7 0.0033 17.2 3.3 1.6 2 0 0 2 2 2 1 Cornifin (SPRR) family tRNA-synt_1 PF00133.17 KLO16588.1 - 5.2e-38 130.4 0.0 4.1e-28 97.7 0.0 2.9 2 1 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.6 KLO16588.1 - 3.7e-16 58.7 0.0 4e-09 35.6 0.0 2.5 2 0 0 2 2 2 2 tRNA synthetases class I (M) Anticodon_1 PF08264.8 KLO16588.1 - 6.2e-15 55.2 0.0 1.6e-14 53.9 0.0 1.7 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.14 KLO16588.1 - 1.4e-10 40.8 0.0 3.9e-10 39.3 0.0 1.7 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1f PF01921.13 KLO16588.1 - 0.012 14.3 0.0 0.024 13.3 0.0 1.4 1 0 0 1 1 1 0 tRNA synthetases class I (K) PseudoU_synth_1 PF01416.15 KLO16589.1 - 5.2e-21 75.0 0.0 2.2e-11 44.0 0.0 3.2 3 2 0 3 3 3 2 tRNA pseudouridine synthase Peptidase_C65 PF10275.4 KLO16590.1 - 4.6e-58 196.4 0.0 5.2e-58 196.2 0.0 1.0 1 0 0 1 1 1 1 Peptidase C65 Otubain OTU PF02338.14 KLO16590.1 - 0.00049 20.6 0.0 0.0072 16.9 0.0 2.2 1 1 0 1 1 1 1 OTU-like cysteine protease WD40 PF00400.27 KLO16591.1 - 1.9e-53 176.5 18.6 2.7e-11 42.8 0.0 7.4 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 KLO16591.1 - 2.2e-07 29.4 8.2 0.039 12.0 0.1 4.7 2 2 2 5 5 5 3 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 KLO16591.1 - 1.9e-06 26.9 1.1 0.65 8.6 0.0 4.6 2 2 2 4 4 4 2 Nup133 N terminal like BBS2_Mid PF14783.1 KLO16591.1 - 8.4e-06 25.5 0.4 5.1 6.9 0.0 4.7 3 2 1 4 4 4 3 Ciliary BBSome complex subunit 2, middle region PQQ_2 PF13360.1 KLO16591.1 - 1.2e-05 24.9 6.1 0.067 12.6 0.2 3.6 2 2 1 3 3 3 2 PQQ-like domain PQQ_3 PF13570.1 KLO16591.1 - 0.00054 20.1 7.4 6.1 7.2 0.0 6.3 6 1 1 7 7 7 2 PQQ-like domain SNF2_N PF00176.18 KLO16592.1 - 1.1e-45 155.6 0.0 1.7e-45 155.1 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 KLO16592.1 - 6.7e-17 61.1 0.0 8.4e-15 54.4 0.0 3.3 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.10 KLO16592.1 - 0.00016 21.5 0.0 0.38 10.5 0.0 3.0 3 0 0 3 3 3 2 Type III restriction enzyme, res subunit VIGSSK PF14773.1 KLO16592.1 - 0.02 14.7 0.0 0.067 13.1 0.0 1.9 1 0 0 1 1 1 0 Helicase-associated putative binding domain, C-terminal RNA_pol_Rpb2_6 PF00562.23 KLO16593.1 - 1.7e-122 408.8 0.2 2.4e-122 408.4 0.1 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.10 KLO16593.1 - 1.8e-56 190.3 0.1 4e-56 189.1 0.0 1.7 2 0 0 2 2 2 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.9 KLO16593.1 - 1.2e-29 103.0 0.0 2.9e-29 101.8 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_7 PF04560.15 KLO16593.1 - 9.1e-29 99.5 0.1 2.4e-28 98.2 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_4 PF04566.8 KLO16593.1 - 3.8e-23 81.0 2.1 9.5e-23 79.7 0.8 2.2 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_3 PF04565.11 KLO16593.1 - 1.1e-20 73.0 0.0 2.5e-20 72.0 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_5 PF04567.12 KLO16593.1 - 4.3e-12 45.8 0.5 8.8e-12 44.8 0.4 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 DUF3810 PF12725.2 KLO16594.1 - 2.9 6.6 10.1 7.3 5.3 0.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3810) Serpentine_r_xa PF03383.10 KLO16594.1 - 4.7 6.9 10.4 5.5 6.7 2.4 2.4 2 0 0 2 2 2 0 Caenorhabditis serpentine receptor-like protein, class xa 7TM_GPCR_Srv PF10323.4 KLO16596.1 - 0.11 11.6 0.0 0.15 11.1 0.0 1.1 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srv ADAM_CR PF08516.7 KLO16597.1 - 0.049 13.6 2.8 0.06 13.4 1.9 1.2 1 0 0 1 1 1 0 ADAM cysteine-rich DUF3328 PF11807.3 KLO16598.1 - 9.9e-12 44.9 1.0 2.4e-11 43.7 0.7 1.8 1 1 0 1 1 1 1 Domain of unknown function (DUF3328) DUF3328 PF11807.3 KLO16599.1 - 1.2e-12 47.9 0.1 1.4e-12 47.7 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) DUF3792 PF12670.2 KLO16600.1 - 0.02 14.7 1.5 0.02 14.7 1.1 3.3 3 1 0 3 3 3 0 Protein of unknown function (DUF3792) Wzy_C PF04932.10 KLO16600.1 - 0.028 14.2 0.4 0.028 14.2 0.3 2.8 2 1 0 2 2 2 0 O-Antigen ligase Peptidase_M17 PF00883.16 KLO16601.1 - 2.2e-105 351.9 0.0 5.4e-105 350.6 0.0 1.6 2 0 0 2 2 2 1 Cytosol aminopeptidase family, catalytic domain Peptidase_M17_N PF02789.12 KLO16601.1 - 0.011 15.4 5.5 0.025 14.3 2.4 2.5 2 1 1 3 3 3 0 Cytosol aminopeptidase family, N-terminal domain EAP30 PF04157.11 KLO16602.1 - 2.7e-37 128.0 0.0 3.5e-37 127.7 0.0 1.1 1 0 0 1 1 1 1 EAP30/Vps36 family Vps36_ESCRT-II PF11605.3 KLO16602.1 - 2.6e-15 55.9 0.0 3.8e-14 52.2 0.0 2.2 1 1 0 1 1 1 1 Vacuolar protein sorting protein 36 Vps36 zf-RanBP PF00641.13 KLO16602.1 - 0.0014 17.7 8.9 0.022 13.8 0.8 2.6 2 1 0 2 2 2 2 Zn-finger in Ran binding protein and others zf-Sec23_Sec24 PF04810.10 KLO16602.1 - 0.042 13.4 2.1 7.5 6.1 0.0 3.2 3 0 0 3 3 3 0 Sec23/Sec24 zinc finger DZR PF12773.2 KLO16602.1 - 0.13 12.0 4.2 0.56 10.0 0.2 2.3 2 0 0 2 2 2 0 Double zinc ribbon IMPDH PF00478.20 KLO16603.1 - 9.8e-134 445.6 0.0 4.3e-119 397.5 0.0 2.0 1 1 0 2 2 2 2 IMP dehydrogenase / GMP reductase domain CBS PF00571.23 KLO16603.1 - 2.7e-14 52.6 0.0 2.4e-06 27.2 0.0 2.5 2 0 0 2 2 2 2 CBS domain FMN_dh PF01070.13 KLO16603.1 - 1.2e-09 37.5 1.4 2.7e-09 36.3 1.0 1.6 1 0 0 1 1 1 1 FMN-dependent dehydrogenase NMO PF03060.10 KLO16603.1 - 4.3e-09 35.9 4.9 1.7e-07 30.6 2.4 2.3 2 0 0 2 2 2 2 Nitronate monooxygenase His_biosynth PF00977.16 KLO16603.1 - 6.2e-06 25.6 2.9 5.9e-05 22.4 1.4 2.6 2 1 0 2 2 2 1 Histidine biosynthesis protein ThiG PF05690.9 KLO16603.1 - 3.6e-05 22.9 1.9 7.1e-05 21.9 0.9 1.8 1 1 0 1 1 1 1 Thiazole biosynthesis protein ThiG DHO_dh PF01180.16 KLO16603.1 - 0.014 14.4 2.7 0.079 11.8 0.4 2.3 2 0 0 2 2 2 0 Dihydroorotate dehydrogenase NUDE_C PF04880.8 KLO16603.1 - 0.018 15.4 1.3 0.037 14.3 0.9 1.5 1 0 0 1 1 1 0 NUDE protein, C-terminal conserved region Dus PF01207.12 KLO16603.1 - 0.12 11.2 0.7 0.47 9.2 0.1 2.0 2 0 0 2 2 2 0 Dihydrouridine synthase (Dus) UQ_con PF00179.21 KLO16605.1 - 5.3e-44 149.0 0.0 6.1e-44 148.8 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme MT-A70 PF05063.9 KLO16606.1 - 3.2e-39 134.2 0.0 9.4e-39 132.7 0.0 1.8 1 1 0 1 1 1 1 MT-A70 Noc2 PF03715.8 KLO16607.1 - 6.6e-94 314.1 0.0 1.3e-93 313.1 0.0 1.5 1 0 0 1 1 1 1 Noc2p family Daxx PF03344.10 KLO16607.1 - 0.87 7.9 24.8 1.5 7.2 17.2 1.3 1 0 0 1 1 1 0 Daxx Family Nop14 PF04147.7 KLO16607.1 - 8.2 4.2 38.5 1 7.2 2.5 2.9 2 1 1 3 3 3 0 Nop14-like family F-box-like PF12937.2 KLO16609.1 - 0.00048 19.8 0.9 0.0049 16.5 0.5 2.4 2 0 0 2 2 2 1 F-box-like Ppx-GppA PF02541.11 KLO16609.1 - 0.13 11.4 0.0 0.2 10.8 0.0 1.2 1 0 0 1 1 1 0 Ppx/GppA phosphatase family F-box-like PF12937.2 KLO16610.1 - 6.5e-06 25.7 1.7 0.00017 21.2 1.2 2.6 1 1 0 1 1 1 1 F-box-like F-box PF00646.28 KLO16610.1 - 0.092 12.4 0.7 23 4.7 0.0 3.5 3 0 0 3 3 3 0 F-box domain F-box-like PF12937.2 KLO16611.1 - 1.4e-06 27.8 0.7 2.1e-05 24.1 0.5 2.5 1 1 0 1 1 1 1 F-box-like Dynamin_N PF00350.18 KLO16612.1 - 2.2e-27 95.9 2.5 1e-26 93.7 0.4 2.7 2 1 0 2 2 2 1 Dynamin family Dynamin_M PF01031.15 KLO16612.1 - 1.3e-24 86.5 0.0 5.4e-11 41.8 0.0 2.7 3 0 0 3 3 3 2 Dynamin central region GED PF02212.13 KLO16612.1 - 3.6e-09 36.3 1.7 1.2e-08 34.7 1.2 1.9 1 0 0 1 1 1 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.18 KLO16612.1 - 0.00017 21.4 0.0 0.0012 18.7 0.0 2.2 1 1 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 KLO16612.1 - 0.06 13.8 0.0 0.16 12.4 0.0 1.8 1 0 0 1 1 1 0 Miro-like protein AAA_28 PF13521.1 KLO16612.1 - 0.084 12.8 3.0 0.37 10.7 0.1 3.0 3 0 0 3 3 3 0 AAA domain FAD_binding_4 PF01565.18 KLO16614.1 - 6.3e-29 100.2 2.9 1e-28 99.5 2.0 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 KLO16614.1 - 7.8e-08 32.1 0.1 1.4e-07 31.3 0.0 1.4 1 0 0 1 1 1 1 Berberine and berberine like CAP_N PF01213.14 KLO16616.1 - 5.2 6.2 6.2 9.4 5.4 4.3 1.4 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal STE PF02200.11 KLO16620.1 - 2e-57 192.0 0.0 3.3e-57 191.3 0.0 1.4 1 0 0 1 1 1 1 STE like transcription factor zf-C2H2 PF00096.21 KLO16620.1 - 5.4e-10 39.0 12.5 1.6e-05 24.9 1.0 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KLO16620.1 - 9e-08 31.9 11.7 0.0018 18.4 1.8 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 KLO16620.1 - 4.6e-07 29.7 2.7 4.6e-07 29.7 1.9 3.4 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_jaz PF12171.3 KLO16620.1 - 0.016 15.2 4.0 0.59 10.3 0.2 2.8 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 KLO16620.1 - 0.037 13.9 0.3 0.086 12.7 0.2 1.6 1 0 0 1 1 1 0 C2H2-type zinc finger zf-met PF12874.2 KLO16620.1 - 0.04 14.1 6.1 0.067 13.4 0.6 3.0 2 0 0 2 2 2 0 Zinc-finger of C2H2 type DUF1687 PF07955.6 KLO16623.1 - 3e-08 33.6 0.0 4.1e-08 33.2 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1687) Mesothelin PF06060.7 KLO16623.1 - 0.03 12.3 0.1 0.03 12.3 0.0 1.1 1 0 0 1 1 1 0 Pre-pro-megakaryocyte potentiating factor precursor (Mesothelin) CRF1 PF10380.4 KLO16623.1 - 0.08 13.2 2.4 1.2 9.5 0.1 2.2 2 0 0 2 2 2 0 Transcription factor CRF1 F-box-like PF12937.2 KLO16624.1 - 0.0002 20.9 3.3 0.71 9.6 1.6 2.6 2 0 0 2 2 2 2 F-box-like LRR_8 PF13855.1 KLO16624.1 - 0.01 15.5 5.7 5.6 6.7 0.0 4.1 2 1 1 3 3 3 0 Leucine rich repeat Aa_trans PF01490.13 KLO16625.1 - 3.1e-29 101.6 38.1 4.5e-29 101.1 26.4 1.2 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein zf-MYND PF01753.13 KLO16626.1 - 7.4e-09 35.3 13.2 7.4e-09 35.3 9.1 1.9 2 0 0 2 2 2 1 MYND finger Dynamin_M PF01031.15 KLO16628.1 - 4e-29 101.3 0.0 1.2e-13 50.4 0.0 2.8 2 0 0 2 2 2 2 Dynamin central region Dynamin_N PF00350.18 KLO16628.1 - 6.9e-25 87.8 0.0 1.6e-24 86.6 0.0 1.7 1 0 0 1 1 1 1 Dynamin family GED PF02212.13 KLO16628.1 - 3.8e-08 33.1 1.2 1.1e-07 31.6 0.8 1.8 1 0 0 1 1 1 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.18 KLO16628.1 - 0.00018 21.4 0.0 0.003 17.5 0.0 2.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase DUF677 PF05055.7 KLO16629.1 - 6.3e-06 25.0 0.2 1.8e-05 23.5 0.0 1.7 1 1 1 2 2 2 1 Protein of unknown function (DUF677) Claudin_2 PF13903.1 KLO16629.1 - 3.5e-05 23.5 0.0 4.5e-05 23.1 0.0 1.2 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction DUF3040 PF11239.3 KLO16629.1 - 0.00077 19.4 0.0 0.0017 18.3 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3040) TBPIP PF07106.8 KLO16629.1 - 0.0022 17.5 0.8 0.0068 15.9 0.7 1.6 2 0 0 2 2 2 1 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) ATG16 PF08614.6 KLO16629.1 - 0.003 17.3 0.2 0.088 12.6 0.2 2.1 2 0 0 2 2 2 1 Autophagy protein 16 (ATG16) DUF2721 PF11026.3 KLO16629.1 - 0.0075 15.9 0.1 0.014 15.0 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2721) SseC PF04888.7 KLO16629.1 - 0.0088 15.4 0.0 0.012 14.9 0.0 1.2 1 0 0 1 1 1 1 Secretion system effector C (SseC) like family TelA PF05816.6 KLO16629.1 - 0.0098 14.6 0.4 0.047 12.3 0.3 1.8 1 1 1 2 2 2 1 Toxic anion resistance protein (TelA) Myosin_tail_1 PF01576.14 KLO16629.1 - 0.012 13.3 2.1 0.017 12.8 1.4 1.1 1 0 0 1 1 1 0 Myosin tail Reo_sigmaC PF04582.7 KLO16629.1 - 0.023 13.8 0.7 0.27 10.3 0.0 2.4 2 1 1 3 3 3 0 Reovirus sigma C capsid protein Med10 PF09748.4 KLO16629.1 - 0.025 14.4 0.1 0.065 13.0 0.1 1.8 1 1 0 1 1 1 0 Transcription factor subunit Med10 of Mediator complex DUF2051 PF09738.4 KLO16629.1 - 0.026 13.8 1.9 0.038 13.2 1.3 1.2 1 0 0 1 1 1 0 Double stranded RNA binding protein (DUF2051) PhoU PF01895.14 KLO16629.1 - 0.027 14.9 0.4 0.16 12.4 0.3 2.2 2 0 0 2 2 2 0 PhoU domain EzrA PF06160.7 KLO16629.1 - 0.034 12.3 0.8 0.14 10.3 0.2 1.9 2 0 0 2 2 2 0 Septation ring formation regulator, EzrA DUF1640 PF07798.6 KLO16629.1 - 0.045 13.7 0.4 0.1 12.6 0.2 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1640) IFT57 PF10498.4 KLO16629.1 - 0.056 12.1 0.3 0.11 11.2 0.2 1.5 2 0 0 2 2 2 0 Intra-flagellar transport protein 57 Cluap1 PF10234.4 KLO16629.1 - 0.062 12.4 0.5 0.084 12.0 0.4 1.2 1 0 0 1 1 1 0 Clusterin-associated protein-1 DUF1664 PF07889.7 KLO16629.1 - 0.081 12.7 2.2 0.65 9.8 0.5 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) Herpes_U30 PF04523.8 KLO16629.1 - 0.1 10.0 0.1 0.12 9.7 0.1 1.1 1 0 0 1 1 1 0 Herpes virus tegument protein U30 INT_SG_DDX_CT_C PF15300.1 KLO16629.1 - 0.11 11.9 0.1 0.24 10.8 0.1 1.5 1 0 0 1 1 1 0 INTS6/SAGE1/DDX26B/CT45 C-terminus ETRAMP PF09716.5 KLO16629.1 - 0.14 12.1 0.1 0.3 11.0 0.0 1.7 1 1 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) TPR_9 PF13371.1 KLO16634.1 - 0.00076 19.2 1.1 0.0021 17.8 0.2 2.1 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.12 KLO16634.1 - 0.0009 18.9 0.0 0.0026 17.5 0.0 1.9 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_14 PF13428.1 KLO16634.1 - 0.0012 19.2 0.3 0.0062 17.0 0.2 2.3 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_11 PF13414.1 KLO16634.1 - 0.0026 17.3 0.2 0.0091 15.6 0.0 2.0 2 0 0 2 2 2 1 TPR repeat TPR_1 PF00515.23 KLO16634.1 - 0.0042 16.6 0.0 0.01 15.4 0.0 1.7 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_6 PF13174.1 KLO16634.1 - 0.016 15.6 0.0 0.068 13.6 0.0 2.2 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_16 PF13432.1 KLO16634.1 - 0.018 15.7 0.2 0.057 14.1 0.2 1.9 1 0 0 1 1 1 0 Tetratricopeptide repeat Suf PF05843.9 KLO16634.1 - 1.7 8.3 9.0 0.72 9.5 2.7 2.4 3 0 0 3 3 3 0 Suppressor of forked protein (Suf) Tyr-DNA_phospho PF06087.7 KLO16637.1 - 7.7e-54 182.9 0.0 1.3e-53 182.2 0.0 1.3 1 0 0 1 1 1 1 Tyrosyl-DNA phosphodiesterase UIM PF02809.15 KLO16637.1 - 2.2e-05 23.6 6.3 9.2e-05 21.6 0.8 2.9 2 0 0 2 2 2 1 Ubiquitin interaction motif PLDc_2 PF13091.1 KLO16637.1 - 0.0017 18.0 0.0 0.22 11.2 0.0 2.7 2 1 0 2 2 2 1 PLD-like domain DUF3348 PF11828.3 KLO16637.1 - 0.13 11.7 1.8 0.31 10.4 1.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3348) Peptidase_S31 PF05578.7 KLO16638.1 - 0.0098 15.1 0.0 0.01 15.0 0.0 1.0 1 0 0 1 1 1 1 Pestivirus NS3 polyprotein peptidase S31 DUF3176 PF11374.3 KLO16639.1 - 0.0035 17.1 5.1 0.24 11.2 0.3 3.1 2 0 0 2 2 2 2 Protein of unknown function (DUF3176) Fimbrial_K88 PF02432.10 KLO16641.1 - 0.16 11.3 0.0 0.32 10.4 0.0 1.4 1 0 0 1 1 1 0 Fimbrial, major and minor subunit GPI-anchored PF10342.4 KLO16642.1 - 2.5e-05 24.6 0.0 5.1e-05 23.6 0.0 1.5 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family GST_N PF02798.15 KLO16644.1 - 5e-18 65.0 0.0 8e-18 64.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 KLO16644.1 - 6.1e-15 55.2 0.0 1.1e-14 54.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 KLO16644.1 - 2.8e-10 40.0 0.0 4.8e-10 39.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 KLO16644.1 - 1.1e-09 38.1 0.0 2.1e-09 37.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 KLO16644.1 - 8.4e-06 25.5 0.1 1.9e-05 24.4 0.1 1.7 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 KLO16644.1 - 0.0069 16.8 0.0 0.01 16.3 0.0 1.5 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain DUF1912 PF08930.5 KLO16644.1 - 0.06 13.4 0.0 0.13 12.3 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1912) Xpo1 PF08389.7 KLO16646.1 - 1.8e-13 50.6 0.3 1.9e-09 37.5 0.0 4.3 3 1 1 4 4 4 2 Exportin 1-like protein IBN_N PF03810.14 KLO16646.1 - 1.6e-05 24.7 0.0 7.3e-05 22.5 0.0 2.2 2 0 0 2 2 2 1 Importin-beta N-terminal domain PMSI1 PF15322.1 KLO16646.1 - 0.11 11.5 0.0 0.26 10.3 0.0 1.5 1 0 0 1 1 1 0 Protein missing in infertile sperm 1, putative Aconitase PF00330.15 KLO16647.1 - 1.4e-175 584.3 0.1 2.6e-175 583.4 0.0 1.4 1 1 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 KLO16647.1 - 6.5e-44 149.2 0.0 1.2e-43 148.3 0.0 1.4 1 0 0 1 1 1 1 Aconitase C-terminal domain UCR_hinge PF02320.11 KLO16648.1 - 1.9e-18 66.1 3.7 3.4e-18 65.3 2.6 1.4 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase hinge protein Sigma70_ner PF04546.8 KLO16648.1 - 0.009 15.6 1.9 0.0094 15.5 1.3 1.2 1 0 0 1 1 1 1 Sigma-70, non-essential region Myc_N PF01056.13 KLO16648.1 - 0.07 12.2 5.3 0.086 11.9 3.7 1.1 1 0 0 1 1 1 0 Myc amino-terminal region Radial_spoke PF04712.7 KLO16648.1 - 0.13 11.0 6.7 0.13 10.9 4.6 1.1 1 0 0 1 1 1 0 Radial spokehead-like protein FAM176 PF14851.1 KLO16648.1 - 0.37 10.4 3.3 0.41 10.3 2.3 1.2 1 0 0 1 1 1 0 FAM176 family TRAP_alpha PF03896.11 KLO16648.1 - 0.6 9.0 3.3 0.73 8.7 2.3 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Daxx PF03344.10 KLO16648.1 - 0.69 8.3 8.9 0.69 8.3 6.1 1.0 1 0 0 1 1 1 0 Daxx Family BSP_II PF05432.6 KLO16648.1 - 0.78 8.9 10.7 0.87 8.8 7.4 1.1 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) GOLD_2 PF13897.1 KLO16648.1 - 2.2 8.5 5.2 2.1 8.5 3.1 1.3 1 1 0 1 1 1 0 Golgi-dynamics membrane-trafficking DUF2890 PF11081.3 KLO16648.1 - 4.9 7.1 9.8 6 6.8 6.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) CHCH PF06747.8 KLO16648.1 - 6.6 6.7 9.1 16 5.5 1.1 2.5 2 0 0 2 2 2 0 CHCH domain PMSR PF01625.16 KLO16649.1 - 1.7e-60 203.4 1.1 2.7e-60 202.7 0.8 1.2 1 0 0 1 1 1 1 Peptide methionine sulfoxide reductase Pkinase PF00069.20 KLO16650.1 - 1.4e-49 168.6 0.0 3.8e-49 167.1 0.0 1.7 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 KLO16650.1 - 2.4e-49 167.7 0.0 3.4e-49 167.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase C1_1 PF00130.17 KLO16650.1 - 2e-07 30.5 1.5 3.9e-07 29.6 1.0 1.4 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) APH PF01636.18 KLO16650.1 - 0.0021 17.8 0.0 0.0043 16.8 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.1 KLO16650.1 - 0.004 16.1 0.0 0.006 15.5 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 KLO16650.1 - 0.012 14.6 0.0 0.019 14.0 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Prok-RING_1 PF14446.1 KLO16650.1 - 0.3 10.8 3.8 0.59 9.9 2.6 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 PHD_2 PF13831.1 KLO16650.1 - 0.34 10.2 1.3 0.35 10.2 0.0 1.7 2 0 0 2 2 2 0 PHD-finger PHD PF00628.24 KLO16650.1 - 0.35 10.5 4.8 0.67 9.6 3.4 1.4 1 0 0 1 1 1 0 PHD-finger Transp_cyt_pur PF02133.10 KLO16652.1 - 1.4e-110 369.8 36.1 1.7e-110 369.6 25.0 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Pkinase_Tyr PF07714.12 KLO16653.1 - 8e-64 215.1 0.0 2.4e-39 134.9 0.0 2.4 2 1 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.20 KLO16653.1 - 1.6e-59 201.1 0.0 5.7e-39 133.8 0.0 2.4 2 0 0 2 2 2 2 Protein kinase domain Kinase-like PF14531.1 KLO16653.1 - 0.0086 15.0 0.0 0.04 12.8 0.0 1.9 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 KLO16653.1 - 0.034 13.8 0.4 0.12 12.0 0.0 2.0 2 0 0 2 2 2 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 KLO16653.1 - 0.1 11.4 0.1 0.1 11.4 0.1 2.3 3 0 0 3 3 3 0 Seadornavirus VP7 ADH_zinc_N PF00107.21 KLO16654.1 - 8.3e-18 64.1 0.0 1.5e-17 63.3 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KLO16654.1 - 1.2e-09 37.9 0.0 2e-09 37.1 0.0 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 KLO16654.1 - 3.6e-08 34.3 0.0 7.2e-08 33.3 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase THF_DHG_CYH_C PF02882.14 KLO16654.1 - 0.13 11.3 0.0 0.24 10.4 0.0 1.4 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Pkinase PF00069.20 KLO16655.1 - 1.9e-44 151.8 0.0 2.8e-44 151.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KLO16655.1 - 6e-38 130.3 0.0 2.2e-37 128.5 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.17 KLO16655.1 - 0.00027 20.3 0.0 0.00089 18.6 0.0 1.7 2 0 0 2 2 2 1 RIO1 family APH PF01636.18 KLO16655.1 - 0.0046 16.7 0.1 0.01 15.6 0.0 1.5 2 0 0 2 2 2 1 Phosphotransferase enzyme family ABC1 PF03109.11 KLO16655.1 - 0.036 14.0 0.0 0.11 12.4 0.0 1.8 2 0 0 2 2 2 0 ABC1 family Kinase-like PF14531.1 KLO16655.1 - 0.068 12.1 0.0 0.14 11.0 0.0 1.5 1 0 0 1 1 1 0 Kinase-like Choline_kinase PF01633.15 KLO16655.1 - 0.091 12.3 0.0 0.16 11.5 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase Transp_cyt_pur PF02133.10 KLO16656.1 - 1.3e-30 106.3 40.8 2e-30 105.7 28.1 1.5 1 1 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Caveolin PF01146.12 KLO16656.1 - 3.1 7.3 7.8 4 7.0 0.5 2.9 1 1 2 3 3 3 0 Caveolin GAPT PF11770.3 KLO16657.1 - 0.1 12.2 0.1 0.24 11.0 0.0 1.6 1 0 0 1 1 1 0 GRB2-binding adapter (GAPT) Pkinase_Tyr PF07714.12 KLO16659.1 - 1.7e-62 210.8 0.0 3.9e-38 131.0 0.0 2.4 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.20 KLO16659.1 - 8.8e-57 192.2 0.0 5e-36 124.1 0.0 2.4 2 1 0 2 2 2 2 Protein kinase domain APH PF01636.18 KLO16659.1 - 0.0054 16.4 0.1 0.021 14.5 0.0 2.0 2 1 0 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.1 KLO16659.1 - 0.18 10.7 0.0 0.84 8.5 0.0 2.0 2 1 0 2 2 2 0 Kinase-like DUF3414 PF11894.3 KLO16660.1 - 4.3e-244 812.9 0.0 5.6e-244 812.5 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3414) Got1 PF04178.7 KLO16661.1 - 2.1e-29 102.0 16.0 2.9e-29 101.5 11.1 1.2 1 0 0 1 1 1 1 Got1/Sft2-like family DUF3357 PF11837.3 KLO16661.1 - 0.35 10.7 0.0 0.35 10.7 0.0 2.8 3 1 1 4 4 4 0 Domain of unknown function (DUF3357) ATP_sub_h PF10775.4 KLO16662.1 - 1.8e-19 69.2 0.7 2.7e-19 68.6 0.5 1.2 1 0 0 1 1 1 1 ATP synthase complex subunit h BTB_2 PF02214.17 KLO16664.1 - 0.0099 16.0 0.1 0.068 13.3 0.0 2.3 2 1 0 2 2 2 1 BTB/POZ domain BTB PF00651.26 KLO16664.1 - 0.018 15.0 0.0 0.028 14.3 0.0 1.2 1 0 0 1 1 1 0 BTB/POZ domain RNA_pol PF00940.14 KLO16665.1 - 9.4e-161 534.8 0.0 1.4e-160 534.2 0.0 1.3 1 0 0 1 1 1 1 DNA-dependent RNA polymerase RPOL_N PF14700.1 KLO16665.1 - 2.2e-72 244.0 1.6 2.2e-72 244.0 1.1 1.8 2 0 0 2 2 2 1 DNA-directed RNA polymerase N-terminal PPR_2 PF13041.1 KLO16665.1 - 0.0043 17.0 0.0 0.011 15.6 0.0 1.7 1 0 0 1 1 1 1 PPR repeat family HORMA PF02301.13 KLO16665.1 - 0.032 13.7 0.1 0.074 12.5 0.1 1.6 1 0 0 1 1 1 0 HORMA domain Peptidase_M28 PF04389.12 KLO16666.1 - 5.5e-26 91.3 0.0 9.7e-26 90.5 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.23 KLO16666.1 - 7.7e-05 22.2 0.0 0.00021 20.8 0.0 1.7 2 0 0 2 2 2 1 Peptidase family M20/M25/M40 Nicastrin PF05450.10 KLO16666.1 - 0.0067 15.7 0.0 0.01 15.0 0.0 1.2 1 0 0 1 1 1 1 Nicastrin Acetyltransf_1 PF00583.19 KLO16667.1 - 1.3e-16 60.4 0.0 2.1e-16 59.7 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 KLO16667.1 - 3.7e-08 33.5 0.0 5.4e-08 32.9 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 KLO16667.1 - 1.3e-07 31.2 0.1 2.2e-07 30.5 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_7 PF13508.1 KLO16667.1 - 1.1e-06 28.6 0.0 1.9e-06 27.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 KLO16667.1 - 1.7e-06 28.0 0.0 3.2e-06 27.0 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 KLO16667.1 - 6.2e-06 26.4 0.0 1e-05 25.7 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 KLO16667.1 - 0.00012 21.9 0.0 0.00019 21.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 KLO16667.1 - 0.008 16.1 0.0 0.013 15.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 KLO16667.1 - 0.04 13.7 0.0 0.071 13.0 0.0 1.3 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase HSP70 PF00012.15 KLO16668.1 - 5.7e-267 886.5 7.8 6.5e-267 886.3 5.4 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 KLO16668.1 - 1.3e-17 63.4 0.5 1.1e-16 60.3 0.1 2.1 2 0 0 2 2 2 1 MreB/Mbl protein DDR PF08841.5 KLO16668.1 - 0.0014 17.5 0.4 0.05 12.4 0.2 2.4 2 0 0 2 2 2 1 Diol dehydratase reactivase ATPase-like domain Hydantoinase_A PF01968.13 KLO16668.1 - 0.029 13.4 5.7 0.063 12.3 0.1 2.8 2 1 1 3 3 3 0 Hydantoinase/oxoprolinase FtsA PF14450.1 KLO16668.1 - 2.9 7.7 7.6 20 5.0 1.4 3.7 2 2 0 2 2 2 0 Cell division protein FtsA Rtt106 PF08512.7 KLO16669.1 - 1.9e-10 40.5 0.0 8e-10 38.5 0.0 2.0 1 1 0 1 1 1 1 Histone chaperone Rttp106-like Peptidase_U40 PF10464.4 KLO16669.1 - 0.029 13.7 0.1 0.053 12.9 0.1 1.3 1 0 0 1 1 1 0 Peptidase U40 BTB PF00651.26 KLO16670.1 - 5.2e-05 23.2 0.0 0.00018 21.4 0.0 1.8 1 1 0 1 1 1 1 BTB/POZ domain BTB PF00651.26 KLO16672.1 - 2.3e-06 27.5 0.1 9.6e-06 25.5 0.0 2.1 2 1 0 2 2 2 1 BTB/POZ domain GF_recep_IV PF14843.1 KLO16672.1 - 0.00024 20.7 0.1 0.00038 20.0 0.1 1.2 1 0 0 1 1 1 1 Growth factor receptor domain IV BTB PF00651.26 KLO16673.1 - 7.2e-06 25.9 0.0 1.3e-05 25.1 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain BTB PF00651.26 KLO16675.1 - 4.2e-06 26.7 0.1 9e-06 25.6 0.0 1.5 1 1 0 1 1 1 1 BTB/POZ domain BTB PF00651.26 KLO16677.1 - 8.3e-05 22.5 0.4 0.00052 19.9 0.3 2.3 2 1 0 2 2 2 1 BTB/POZ domain BTB PF00651.26 KLO16678.1 - 4.7e-06 26.5 0.2 1.6e-05 24.8 0.1 1.9 1 1 0 1 1 1 1 BTB/POZ domain ApoC-I PF04691.7 KLO16678.1 - 0.027 14.1 0.1 0.081 12.6 0.0 1.8 2 0 0 2 2 2 0 Apolipoprotein C-I (ApoC-1) BTB PF00651.26 KLO16679.1 - 1.1e-07 31.8 0.0 2.6e-07 30.6 0.0 1.6 1 0 0 1 1 1 1 BTB/POZ domain BTB PF00651.26 KLO16680.1 - 0.0012 18.8 0.4 0.004 17.1 0.3 1.9 1 1 0 1 1 1 1 BTB/POZ domain zf-CCHC_4 PF14392.1 KLO16680.1 - 2.1 8.1 4.1 0.78 9.4 0.7 1.9 2 0 0 2 2 2 0 Zinc knuckle BTB PF00651.26 KLO16681.1 - 5.3e-06 26.3 0.2 3.5e-05 23.7 0.2 2.1 1 1 0 1 1 1 1 BTB/POZ domain zf-RVT PF13966.1 KLO16684.1 - 0.001 19.3 0.5 0.002 18.3 0.3 1.6 1 1 0 1 1 1 1 zinc-binding in reverse transcriptase RNase_H PF00075.19 KLO16684.1 - 0.0045 17.3 0.1 0.012 15.9 0.0 1.7 2 0 0 2 2 2 1 RNase H FtsL PF04999.8 KLO16684.1 - 0.062 13.0 0.1 0.11 12.1 0.0 1.4 1 0 0 1 1 1 0 Cell division protein FtsL BTB PF00651.26 KLO16685.1 - 9.4e-05 22.3 0.0 0.00027 20.8 0.0 1.8 1 1 0 1 1 1 1 BTB/POZ domain APH PF01636.18 KLO16686.1 - 2e-13 50.6 0.0 6.7e-12 45.6 0.0 2.4 2 1 0 2 2 2 1 Phosphotransferase enzyme family DUF1679 PF07914.6 KLO16686.1 - 8.8e-05 21.3 0.0 0.029 13.0 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF1679) DSHCT PF08148.7 KLO16686.1 - 0.12 11.5 0.0 0.33 10.1 0.0 1.7 1 0 0 1 1 1 0 DSHCT (NUC185) domain BTB PF00651.26 KLO16687.1 - 6.2e-05 22.9 0.2 9.2e-05 22.3 0.1 1.5 1 1 0 1 1 1 1 BTB/POZ domain APH PF01636.18 KLO16689.1 - 5.1e-15 55.8 0.0 1.8e-14 54.0 0.0 1.9 2 1 0 2 2 2 1 Phosphotransferase enzyme family DUF1679 PF07914.6 KLO16689.1 - 2.3e-07 29.8 0.0 0.0028 16.3 0.0 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF1679) Aminotran_4 PF01063.14 KLO16689.1 - 0.047 13.1 0.0 0.31 10.4 0.0 2.1 2 0 0 2 2 2 0 Aminotransferase class IV BTB PF00651.26 KLO16690.1 - 1.9e-07 31.0 0.0 3.4e-07 30.2 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain Thioredoxin_3 PF13192.1 KLO16690.1 - 0.11 12.3 0.0 0.24 11.2 0.0 1.5 1 0 0 1 1 1 0 Thioredoxin domain zf-C3HC4 PF00097.20 KLO16691.1 - 2.3e-06 27.1 13.4 7.4e-06 25.5 9.3 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KLO16691.1 - 2e-05 24.5 14.4 2e-05 24.5 10.0 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KLO16691.1 - 0.0016 18.0 17.9 0.0016 18.0 12.4 2.0 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.1 KLO16691.1 - 0.0053 16.2 12.3 0.026 14.0 8.5 2.0 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_2 PF13639.1 KLO16691.1 - 0.01 15.6 15.1 0.01 15.6 10.5 2.6 3 1 1 4 4 4 0 Ring finger domain zf-C3HC4_4 PF15227.1 KLO16691.1 - 0.032 14.1 8.7 0.12 12.2 6.1 2.0 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.1 KLO16691.1 - 0.12 12.0 23.1 0.063 13.0 13.1 2.5 2 1 1 3 3 3 0 zinc-RING finger domain BTB PF00651.26 KLO16692.1 - 7.9e-05 22.6 0.1 0.00025 21.0 0.1 1.9 1 1 0 1 1 1 1 BTB/POZ domain Pkinase_Tyr PF07714.12 KLO16694.1 - 1.9e-30 105.8 0.0 2.3e-30 105.5 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 KLO16694.1 - 2.3e-29 102.3 0.0 2.6e-29 102.1 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.1 KLO16694.1 - 0.00015 20.8 0.0 0.0002 20.4 0.0 1.1 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.17 KLO16694.1 - 0.0054 16.0 0.0 0.0087 15.4 0.0 1.3 1 0 0 1 1 1 1 RIO1 family APH PF01636.18 KLO16694.1 - 0.0071 16.1 0.0 0.011 15.4 0.0 1.3 1 1 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_Tyr PF07714.12 KLO16695.1 - 7.2e-44 149.8 0.0 1.4e-43 148.8 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 KLO16695.1 - 5.3e-41 140.4 0.0 1.8e-40 138.7 0.0 1.9 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.1 KLO16695.1 - 1.3e-06 27.5 0.0 2.4e-06 26.7 0.0 1.3 1 0 0 1 1 1 1 Kinase-like DUF4259 PF14078.1 KLO16695.1 - 0.02 15.3 7.7 3.4 8.1 0.0 4.0 3 1 1 4 4 4 0 Domain of unknown function (DUF4259) HEAT PF02985.17 KLO16695.1 - 0.021 14.8 1.9 37 4.7 0.1 4.0 3 0 0 3 3 3 0 HEAT repeat Mod_r PF07200.8 KLO16695.1 - 0.7 9.7 5.2 0.72 9.7 1.1 2.4 2 0 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein Pkinase_Tyr PF07714.12 KLO16696.1 - 1.7e-38 132.2 0.0 2.8e-38 131.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 KLO16696.1 - 1.3e-37 129.3 0.0 2.4e-37 128.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.1 KLO16696.1 - 5e-09 35.5 0.0 9.9e-09 34.5 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Pkinase_Tyr PF07714.12 KLO16697.1 - 4.1e-10 39.1 0.0 6.6e-10 38.4 0.0 1.3 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 KLO16697.1 - 2.6e-07 30.0 0.0 2.9e-07 29.9 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.1 KLO16697.1 - 0.075 11.9 0.0 0.075 11.9 0.0 1.1 1 0 0 1 1 1 0 Kinase-like Pkinase PF00069.20 KLO16698.1 - 0.0011 18.1 0.0 0.0013 17.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KLO16698.1 - 0.003 16.6 0.0 0.0039 16.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase BTB PF00651.26 KLO16701.1 - 0.00014 21.7 1.2 0.00065 19.6 0.8 2.1 1 1 0 1 1 1 1 BTB/POZ domain BTB PF00651.26 KLO16702.1 - 7.6e-07 29.0 0.1 3.3e-06 27.0 0.0 2.1 2 1 0 2 2 2 1 BTB/POZ domain F-box-like PF12937.2 KLO16703.1 - 7e-05 22.4 0.0 0.00021 20.9 0.0 1.8 1 0 0 1 1 1 1 F-box-like SUR7 PF06687.7 KLO16704.1 - 2.3e-11 43.6 19.4 2.1e-10 40.5 13.1 2.3 1 1 0 1 1 1 1 SUR7/PalI family DUF4381 PF14316.1 KLO16704.1 - 0.1 12.7 0.0 0.1 12.7 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4381) Claudin_2 PF13903.1 KLO16704.1 - 0.15 11.7 14.4 0.14 11.7 8.9 1.7 1 1 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction F-box-like PF12937.2 KLO16705.1 - 0.0043 16.7 0.0 0.018 14.7 0.0 2.0 2 0 0 2 2 2 1 F-box-like Histone PF00125.19 KLO16706.1 - 7.3e-23 80.4 0.2 1e-22 79.9 0.1 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 KLO16706.1 - 0.0033 17.4 0.0 0.0056 16.7 0.0 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone PS_Dcarbxylase PF02666.10 KLO16707.1 - 4.3e-43 146.9 0.0 5.6e-43 146.5 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase BTB PF00651.26 KLO16708.1 - 2.6e-06 27.3 0.1 9.3e-06 25.5 0.0 2.0 1 1 0 1 1 1 1 BTB/POZ domain F-box-like PF12937.2 KLO16712.1 - 0.0076 15.9 0.1 0.018 14.7 0.1 1.6 1 0 0 1 1 1 1 F-box-like F-box-like PF12937.2 KLO16713.1 - 0.00037 20.1 0.0 0.00083 19.0 0.0 1.6 1 0 0 1 1 1 1 F-box-like F-box-like PF12937.2 KLO16714.1 - 0.00013 21.6 0.1 0.00034 20.2 0.0 1.7 2 0 0 2 2 2 1 F-box-like Cupin_2 PF07883.6 KLO16715.1 - 7.9e-07 28.4 0.0 1.5e-06 27.5 0.0 1.5 1 0 0 1 1 1 1 Cupin domain Cupin_6 PF12852.2 KLO16715.1 - 0.0064 16.1 0.0 0.0089 15.6 0.0 1.2 1 0 0 1 1 1 1 Cupin AraC_binding PF02311.14 KLO16715.1 - 0.1 12.2 0.0 0.17 11.5 0.0 1.4 1 0 0 1 1 1 0 AraC-like ligand binding domain Pkinase_Tyr PF07714.12 KLO16717.1 - 1.3e-33 116.1 0.0 1.7e-33 115.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 KLO16717.1 - 1.8e-32 112.5 0.0 2.4e-32 112.1 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.1 KLO16717.1 - 0.00035 19.6 0.0 0.00048 19.1 0.0 1.1 1 0 0 1 1 1 1 Kinase-like DDE_3 PF13358.1 KLO16718.1 - 5.6e-08 32.6 0.0 7.9e-08 32.1 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease YdjO PF14169.1 KLO16718.1 - 0.023 14.1 0.0 0.035 13.5 0.0 1.4 1 0 0 1 1 1 0 Cold-inducible protein YdjO DDE_3 PF13358.1 KLO16719.1 - 5.9e-09 35.8 0.0 7.6e-09 35.4 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.13 KLO16719.1 - 0.00017 21.5 0.0 0.00026 20.9 0.0 1.3 1 0 0 1 1 1 1 Transposase HTH_33 PF13592.1 KLO16719.1 - 0.021 14.3 0.0 0.039 13.4 0.0 1.4 1 0 0 1 1 1 0 Winged helix-turn helix HTH_29 PF13551.1 KLO16719.1 - 0.023 14.8 0.0 0.035 14.2 0.0 1.3 1 0 0 1 1 1 0 Winged helix-turn helix DDE_Tnp_ISAZ013 PF07592.6 KLO16719.1 - 0.079 11.6 0.0 0.1 11.3 0.0 1.1 1 0 0 1 1 1 0 Rhodopirellula transposase DDE domain Kelch_3 PF13415.1 KLO16720.1 - 0.066 13.3 0.0 0.2 11.8 0.0 1.9 1 0 0 1 1 1 0 Galactose oxidase, central domain NOA36 PF06524.7 KLO16720.1 - 3.3 6.8 9.6 8.1 5.5 6.7 1.7 1 0 0 1 1 1 0 NOA36 protein Nucleoplasmin PF03066.10 KLO16720.1 - 5.8 6.4 17.8 1.2 8.6 9.0 2.2 2 0 0 2 2 2 0 Nucleoplasmin Fez1 PF06818.10 KLO16721.1 - 0.44 10.5 14.5 1.4 8.9 10.0 1.8 1 0 0 1 1 1 0 Fez1 Yae1_N PF09811.4 KLO16721.1 - 0.83 9.2 6.5 0.43 10.1 3.0 1.6 2 0 0 2 2 2 0 Essential protein Yae1, N terminal FliL PF03748.9 KLO16721.1 - 5.5 7.0 9.3 2.8 7.9 2.8 2.9 3 1 0 3 3 3 0 Flagellar basal body-associated protein FliL GATA PF00320.22 KLO16722.1 - 1e-27 95.1 12.5 8.3e-16 57.0 1.1 2.3 2 0 0 2 2 2 2 GATA zinc finger Zn_Tnp_IS1595 PF12760.2 KLO16722.1 - 0.013 15.2 5.5 0.69 9.7 0.8 2.3 2 0 0 2 2 2 0 Transposase zinc-ribbon domain ArfGap PF01412.13 KLO16722.1 - 0.027 14.2 1.7 2.3 8.0 0.0 2.2 2 0 0 2 2 2 0 Putative GTPase activating protein for Arf DZR PF12773.2 KLO16722.1 - 0.039 13.7 9.3 2.6 7.9 1.0 2.8 1 1 1 2 2 2 0 Double zinc ribbon DUF3268 PF11672.3 KLO16722.1 - 0.042 13.9 2.5 0.12 12.4 0.6 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3268) eIF-5_eIF-2B PF01873.12 KLO16722.1 - 0.057 13.0 4.3 1.9 8.1 0.2 2.1 2 0 0 2 2 2 0 Domain found in IF2B/IF5 RRN7 PF11781.3 KLO16722.1 - 0.061 12.8 5.2 0.066 12.7 0.3 2.9 3 0 0 3 3 3 0 RNA polymerase I-specific transcription initiation factor Rrn7 Cytochrom_c3_2 PF14537.1 KLO16722.1 - 0.068 13.5 5.6 0.8 10.0 0.5 2.1 1 1 0 1 1 1 0 Cytochrome c3 TF_Zn_Ribbon PF08271.7 KLO16722.1 - 0.18 11.1 7.7 0.41 10.0 0.4 2.8 2 1 0 2 2 2 0 TFIIB zinc-binding zf-Sec23_Sec24 PF04810.10 KLO16722.1 - 0.19 11.3 0.3 0.19 11.3 0.2 2.4 3 0 0 3 3 3 0 Sec23/Sec24 zinc finger COX5B PF01215.14 KLO16722.1 - 0.28 10.8 3.0 10 5.7 0.1 2.5 2 1 1 3 3 3 0 Cytochrome c oxidase subunit Vb Elf1 PF05129.8 KLO16722.1 - 0.56 9.9 3.9 9.8 5.9 0.2 2.7 1 1 2 3 3 3 0 Transcription elongation factor Elf1 like zf-CHY PF05495.7 KLO16722.1 - 0.83 9.8 4.0 2.8 8.1 0.2 2.3 1 1 0 2 2 2 0 CHY zinc finger FYVE PF01363.16 KLO16722.1 - 0.9 9.4 6.2 3.7 7.5 4.3 2.1 1 1 0 1 1 1 0 FYVE zinc finger Cytochrom_CIII PF02085.11 KLO16722.1 - 0.93 9.6 5.1 9.2 6.4 3.4 2.0 1 1 1 2 2 2 0 Class III cytochrome C family Cytochrome_C7 PF14522.1 KLO16722.1 - 1 9.0 8.5 1.4 8.6 3.1 2.2 1 1 1 2 2 2 0 Cytochrome c7 LIM PF00412.17 KLO16722.1 - 1.8 8.6 6.7 13 5.9 0.3 2.5 2 1 0 2 2 2 0 LIM domain zf-RING_3 PF14369.1 KLO16722.1 - 1.9 8.5 5.1 2.3 8.2 0.4 2.6 2 1 0 2 2 2 0 zinc-finger C1_3 PF07649.7 KLO16722.1 - 2.1 8.4 5.8 10 6.2 0.1 2.9 3 0 0 3 3 3 0 C1-like domain OrfB_Zn_ribbon PF07282.6 KLO16722.1 - 2.1 8.0 8.8 4.7 6.9 0.9 2.8 2 1 1 3 3 3 0 Putative transposase DNA-binding domain DNA_RNApol_7kD PF03604.8 KLO16722.1 - 2.2 7.8 7.0 15 5.1 0.5 3.5 3 1 0 3 3 3 0 DNA directed RNA polymerase, 7 kDa subunit Zn-ribbon_8 PF09723.5 KLO16722.1 - 2.7 7.9 11.4 10 6.1 0.2 3.8 2 2 2 4 4 4 0 Zinc ribbon domain HypA PF01155.14 KLO16722.1 - 4.8 6.8 7.6 31 4.2 1.6 2.8 1 1 1 2 2 2 0 Hydrogenase expression/synthesis hypA family zinc-ribbons_6 PF07191.7 KLO16722.1 - 7.9 6.3 7.2 39 4.1 0.1 2.9 2 1 0 2 2 2 0 zinc-ribbons HET PF06985.6 KLO16723.1 - 2.1e-06 27.9 0.7 0.00016 21.8 0.0 2.5 1 1 0 2 2 2 2 Heterokaryon incompatibility protein (HET) CENP-B_N PF04218.8 KLO16723.1 - 0.0034 16.7 0.2 0.0077 15.6 0.1 1.6 1 0 0 1 1 1 1 CENP-B N-terminal DNA-binding domain zf-C2H2 PF00096.21 KLO16724.1 - 5.5e-09 35.8 19.6 0.00061 19.9 0.3 4.8 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KLO16724.1 - 1.8e-08 34.1 21.3 0.12 12.7 0.5 4.8 4 0 0 4 4 4 4 C2H2-type zinc finger HET PF06985.6 KLO16724.1 - 4.8e-08 33.2 0.9 7.6e-06 26.1 0.0 2.5 2 0 0 2 2 2 2 Heterokaryon incompatibility protein (HET) DUF2225 PF09986.4 KLO16724.1 - 0.15 11.4 0.9 0.27 10.6 0.6 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2225) zf-H2C2_2 PF13465.1 KLO16724.1 - 5.6 7.4 22.9 1.1 9.7 0.7 4.4 4 0 0 4 4 4 0 Zinc-finger double domain Na_H_Exchanger PF00999.16 KLO16725.1 - 7.7e-58 195.8 28.7 9.1e-58 195.5 19.9 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family YrhC PF14143.1 KLO16725.1 - 0.11 12.4 2.8 3.5 7.6 0.4 2.7 2 0 0 2 2 2 0 YrhC-like protein Amino_oxidase PF01593.19 KLO16726.1 - 2e-13 50.2 0.0 4.3e-11 42.5 0.0 2.4 2 1 0 2 2 2 2 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 KLO16726.1 - 1.1e-12 47.7 0.0 4e-12 45.9 0.0 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 KLO16726.1 - 0.00022 21.0 0.0 0.25 11.0 0.0 2.5 2 0 0 2 2 2 2 FAD-NAD(P)-binding DAO PF01266.19 KLO16726.1 - 0.00057 18.8 0.0 0.0036 16.2 0.0 2.0 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 KLO16726.1 - 0.0071 16.4 0.0 0.016 15.3 0.0 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 KLO16726.1 - 0.032 14.1 0.0 1.5 8.6 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Integrase_DNA PF02920.10 KLO16726.1 - 0.1 11.9 0.0 0.25 10.7 0.0 1.6 1 0 0 1 1 1 0 DNA binding domain of tn916 integrase FAD_binding_2 PF00890.19 KLO16726.1 - 0.19 10.5 0.0 0.28 9.9 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain Kinesin PF00225.18 KLO16727.1 - 4.8e-92 308.2 0.0 7.6e-92 307.5 0.0 1.3 1 0 0 1 1 1 1 Kinesin motor domain DUF1340 PF07067.6 KLO16727.1 - 0.046 12.8 0.1 0.085 12.0 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1340) Asp PF00026.18 KLO16728.1 - 5.4e-39 134.2 0.3 7.3e-39 133.8 0.2 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 KLO16728.1 - 3.5e-05 23.8 2.6 0.00041 20.3 0.7 2.5 2 0 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 KLO16728.1 - 0.018 15.5 0.9 1.4 9.4 0.3 3.0 2 1 0 2 2 2 0 Aspartyl protease SNF2_N PF00176.18 KLO16729.1 - 1.9e-54 184.4 0.0 2.6e-54 184.0 0.0 1.1 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 KLO16729.1 - 2e-13 49.9 0.0 4.8e-13 48.7 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HDA2-3 PF11496.3 KLO16729.1 - 6.3e-08 31.7 1.7 5.2e-07 28.7 0.9 2.6 1 1 1 2 2 2 1 Class II histone deacetylase complex subunits 2 and 3 Aldo_ket_red PF00248.16 KLO16730.1 - 5.6e-39 133.6 0.0 6.4e-39 133.4 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family DUF3102 PF11300.3 KLO16730.1 - 0.028 14.4 0.0 0.05 13.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3102) Pkinase PF00069.20 KLO16731.1 - 4.1e-75 252.2 0.0 4.7e-75 252.1 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KLO16731.1 - 2.7e-33 115.1 0.0 3.4e-33 114.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 KLO16731.1 - 0.0006 19.6 0.0 0.006 16.3 0.0 2.0 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.1 KLO16731.1 - 0.022 13.7 0.0 0.18 10.7 0.0 2.0 1 1 1 2 2 2 0 Kinase-like Seadorna_VP7 PF07387.6 KLO16731.1 - 0.072 11.9 0.0 0.12 11.2 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 FKBP_C PF00254.23 KLO16732.1 - 1.9e-31 107.9 0.0 2.2e-31 107.7 0.0 1.1 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase IGR PF09597.5 KLO16736.1 - 3.6e-16 58.8 0.1 5.2e-16 58.2 0.1 1.3 1 0 0 1 1 1 1 IGR protein motif Mon1 PF03164.9 KLO16737.1 - 7.9e-95 317.8 0.0 2.6e-66 223.9 0.0 2.1 2 0 0 2 2 2 2 Trafficking protein Mon1 CMAS PF02353.15 KLO16738.1 - 2.1e-61 207.4 0.7 2.7e-48 164.4 0.0 2.8 2 1 0 2 2 2 2 Mycolic acid cyclopropane synthetase Methyltransf_18 PF12847.2 KLO16738.1 - 1.5e-07 32.0 0.0 3.1e-07 30.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KLO16738.1 - 1.6e-06 27.9 0.0 2.9e-06 27.1 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KLO16738.1 - 3.5e-05 24.2 0.0 6.9e-05 23.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KLO16738.1 - 0.00027 21.3 0.0 0.00066 20.1 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KLO16738.1 - 0.0011 18.6 0.0 0.002 17.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain RrnaAD PF00398.15 KLO16738.1 - 0.0059 15.6 0.0 0.024 13.6 0.0 1.9 2 0 0 2 2 2 1 Ribosomal RNA adenine dimethylase MTS PF05175.9 KLO16738.1 - 0.013 14.8 0.0 0.024 14.0 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_26 PF13659.1 KLO16738.1 - 0.11 12.4 0.0 0.21 11.6 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Rif1_N PF12231.3 KLO16739.1 - 0.038 12.9 3.8 0.033 13.1 1.6 1.6 2 0 0 2 2 2 0 Rap1-interacting factor 1 N terminal EBP PF05241.7 KLO16740.1 - 7.8e-63 211.0 8.6 1e-62 210.6 6.0 1.0 1 0 0 1 1 1 1 Emopamil binding protein Form_Nir_trans PF01226.12 KLO16740.1 - 0.39 9.5 5.7 0.076 11.9 0.7 1.9 2 0 0 2 2 2 0 Formate/nitrite transporter zf-MYND PF01753.13 KLO16741.1 - 5.3e-11 42.2 19.2 9.2e-11 41.4 13.3 1.4 1 0 0 1 1 1 1 MYND finger zinc_ribbon_2 PF13240.1 KLO16741.1 - 5.3 6.6 8.5 0.36 10.3 0.3 2.6 2 1 0 2 2 2 0 zinc-ribbon domain OST3_OST6 PF04756.8 KLO16744.1 - 0.19 11.3 3.8 0.3 10.6 0.0 2.6 3 0 0 3 3 3 0 OST3 / OST6 family OST3_OST6 PF04756.8 KLO16745.1 - 0.038 13.5 1.1 3.8 7.0 0.0 2.6 3 0 0 3 3 3 0 OST3 / OST6 family HEAT PF02985.17 KLO16746.1 - 0.0096 15.9 0.0 0.032 14.2 0.0 2.0 1 0 0 1 1 1 1 HEAT repeat FSH1 PF03959.8 KLO16747.1 - 0.036 13.4 0.1 0.046 13.1 0.1 1.2 1 0 0 1 1 1 0 Serine hydrolase (FSH1) zf-MYND PF01753.13 KLO16748.1 - 1.4e-09 37.6 13.2 2.5e-09 36.8 9.1 1.4 1 0 0 1 1 1 1 MYND finger zf-Mss51 PF13824.1 KLO16748.1 - 2 8.3 6.5 5.4 6.9 4.5 1.7 1 0 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 zf-C2H2 PF00096.21 KLO16749.1 - 2e-07 30.9 2.4 0.001 19.2 0.0 3.0 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KLO16749.1 - 3.8e-05 23.7 9.7 0.00074 19.6 0.0 3.3 3 0 0 3 3 3 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 KLO16749.1 - 0.0048 17.1 7.4 0.058 13.7 0.0 3.1 3 0 0 3 3 3 2 Zinc-finger double domain DUF3776 PF12618.3 KLO16749.1 - 2.4 8.7 8.1 0.47 11.0 1.9 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF3776) Linker_histone PF00538.14 KLO16750.1 - 0.0003 20.8 0.0 0.00048 20.1 0.0 1.3 1 0 0 1 1 1 1 linker histone H1 and H5 family NmrA PF05368.8 KLO16751.1 - 6.3e-31 107.4 1.6 7.7e-31 107.1 1.1 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 KLO16751.1 - 4.5e-09 36.5 0.1 6.6e-09 36.0 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding TrkA_N PF02254.13 KLO16751.1 - 0.00014 21.8 0.1 0.0004 20.3 0.1 1.8 1 0 0 1 1 1 1 TrkA-N domain 3Beta_HSD PF01073.14 KLO16751.1 - 0.0017 17.1 0.0 0.0025 16.5 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.20 KLO16751.1 - 0.02 14.8 0.7 0.073 12.9 0.0 2.1 2 0 0 2 2 2 0 short chain dehydrogenase Flavodoxin_1 PF00258.20 KLO16751.1 - 0.03 14.2 0.7 0.11 12.5 0.1 2.1 2 0 0 2 2 2 0 Flavodoxin Zn_clus PF00172.13 KLO16752.1 - 2e-07 30.8 8.5 3.8e-07 29.9 5.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF4551 PF15087.1 KLO16752.1 - 0.53 8.5 2.6 0.89 7.8 1.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) EMP24_GP25L PF01105.19 KLO16753.1 - 0.026 14.2 0.0 0.054 13.2 0.0 1.5 1 0 0 1 1 1 0 emp24/gp25L/p24 family/GOLD Pyr_redox_3 PF13738.1 KLO16754.1 - 1.3e-25 90.6 0.0 5e-24 85.4 0.0 2.6 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 KLO16754.1 - 7.6e-22 77.2 0.0 2.6e-21 75.4 0.0 1.8 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.1 KLO16754.1 - 1.6e-12 46.9 0.1 2.2e-09 36.6 0.0 3.0 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 KLO16754.1 - 7.6e-10 39.0 0.0 5.1e-07 29.7 0.0 2.3 1 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 KLO16754.1 - 1.7e-06 28.3 0.2 0.1 13.0 0.0 2.9 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.15 KLO16754.1 - 1.9e-06 27.9 0.1 0.014 15.4 0.0 2.4 2 0 0 2 2 2 2 Shikimate / quinate 5-dehydrogenase NAD_binding_9 PF13454.1 KLO16754.1 - 1.5e-05 24.8 0.2 0.12 12.1 0.0 3.6 4 0 0 4 4 4 2 FAD-NAD(P)-binding TrkA_N PF02254.13 KLO16754.1 - 0.00012 21.9 0.0 0.06 13.3 0.0 2.5 2 0 0 2 2 2 1 TrkA-N domain Thi4 PF01946.12 KLO16754.1 - 0.00031 19.8 0.1 0.0025 16.9 0.0 2.2 2 0 0 2 2 2 1 Thi4 family DAO PF01266.19 KLO16754.1 - 0.00033 19.6 0.0 0.0015 17.4 0.0 2.2 1 1 0 1 1 1 1 FAD dependent oxidoreductase CPSase_L_chain PF00289.17 KLO16754.1 - 0.0009 19.3 0.1 0.21 11.7 0.0 2.4 2 0 0 2 2 2 1 Carbamoyl-phosphate synthase L chain, N-terminal domain NAD_binding_7 PF13241.1 KLO16754.1 - 0.0011 19.2 0.0 0.38 11.0 0.0 2.4 2 0 0 2 2 2 1 Putative NAD(P)-binding 2-Hacid_dh_C PF02826.14 KLO16754.1 - 0.0021 17.2 0.0 0.34 10.0 0.0 2.4 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Lycopene_cycl PF05834.7 KLO16754.1 - 0.0033 16.3 0.2 0.059 12.2 0.0 2.5 3 0 0 3 3 3 1 Lycopene cyclase protein FAD_binding_3 PF01494.14 KLO16754.1 - 0.0045 16.1 0.1 0.0096 15.0 0.0 1.6 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.9 KLO16754.1 - 0.015 13.7 0.1 0.11 10.9 0.0 2.0 2 0 0 2 2 2 0 HI0933-like protein DUF2338 PF10100.4 KLO16754.1 - 0.035 12.4 0.1 1.8 6.8 0.0 2.1 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2338) F420_oxidored PF03807.12 KLO16754.1 - 0.044 14.2 0.0 4.5 7.7 0.0 2.8 3 0 0 3 3 2 0 NADP oxidoreductase coenzyme F420-dependent Amino_oxidase PF01593.19 KLO16754.1 - 0.052 12.6 0.0 0.075 12.0 0.0 1.2 1 0 0 1 1 1 0 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 KLO16754.1 - 0.063 13.3 0.0 0.26 11.3 0.0 2.1 2 0 0 2 2 1 0 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 KLO16754.1 - 0.063 12.1 0.1 0.13 11.0 0.1 1.5 1 0 0 1 1 1 0 FAD binding domain GIDA PF01134.17 KLO16754.1 - 0.11 11.2 0.1 3.2 6.4 0.0 2.2 2 0 0 2 2 2 0 Glucose inhibited division protein A ThiF PF00899.16 KLO16754.1 - 0.12 12.2 0.1 22 4.8 0.0 2.5 2 0 0 2 2 2 0 ThiF family ELFV_dehydrog PF00208.16 KLO16754.1 - 0.12 11.8 0.2 1.4 8.4 0.1 2.1 2 0 0 2 2 2 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase DUF498 PF04430.9 KLO16754.1 - 0.15 11.6 0.0 1.6 8.3 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF498/DUF598) 3HCDH_N PF02737.13 KLO16754.1 - 0.19 11.3 0.4 5.7 6.5 0.0 2.3 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Abhydrolase_3 PF07859.8 KLO16755.1 - 6.8e-21 74.8 0.1 4.4e-20 72.1 0.1 2.2 2 1 0 2 2 2 1 alpha/beta hydrolase fold DUF2424 PF10340.4 KLO16755.1 - 3.6e-11 42.3 0.0 8.4e-11 41.1 0.0 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF2424) NmrA PF05368.8 KLO16756.1 - 4.3e-36 124.3 0.1 5.7e-36 123.9 0.1 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 KLO16756.1 - 1.3e-08 35.1 0.1 1.5e-08 34.8 0.1 1.2 1 0 0 1 1 1 1 NADH(P)-binding TrkA_N PF02254.13 KLO16756.1 - 0.0047 16.9 0.0 0.013 15.5 0.0 1.7 1 0 0 1 1 1 1 TrkA-N domain 3Beta_HSD PF01073.14 KLO16756.1 - 0.0052 15.5 0.0 0.0066 15.1 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family KR PF08659.5 KLO16756.1 - 0.0072 16.0 0.0 0.014 15.0 0.0 1.4 1 0 0 1 1 1 1 KR domain adh_short PF00106.20 KLO16756.1 - 0.03 14.2 0.1 0.086 12.7 0.0 1.7 1 0 0 1 1 1 0 short chain dehydrogenase Semialdhyde_dh PF01118.19 KLO16756.1 - 0.12 12.6 0.1 0.37 11.0 0.0 1.8 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Abhydrolase_6 PF12697.2 KLO16758.1 - 3e-06 27.3 0.0 4.7e-06 26.6 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KLO16758.1 - 1.1e-05 25.2 0.0 1.6e-05 24.6 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Ser_hydrolase PF06821.8 KLO16758.1 - 0.0031 17.1 0.0 0.0049 16.4 0.0 1.3 1 0 0 1 1 1 1 Serine hydrolase Pyridox_oxidase PF01243.15 KLO16759.1 - 4e-21 74.8 0.0 6.2e-21 74.2 0.0 1.3 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase PNPOx_C PF10590.4 KLO16759.1 - 5.1e-20 70.6 2.4 1.2e-19 69.5 1.7 1.6 1 0 0 1 1 1 1 Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region Pyridox_oxase_2 PF12766.2 KLO16759.1 - 2.1e-05 24.7 0.0 3.8e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase zf-RING_6 PF14835.1 KLO16760.1 - 0.00045 19.9 9.4 0.00045 19.9 6.5 2.6 2 1 0 2 2 2 1 zf-RING of BARD1-type protein zf-C3HC4_3 PF13920.1 KLO16760.1 - 0.00054 19.5 9.8 0.00054 19.5 6.8 3.9 4 0 0 4 4 4 2 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KLO16760.1 - 0.00099 18.8 12.8 0.00099 18.8 8.8 3.8 3 1 0 3 3 3 1 Ring finger domain zf-C3HC4_2 PF13923.1 KLO16760.1 - 0.0024 17.8 15.3 0.0024 17.8 10.6 3.9 4 1 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KLO16760.1 - 0.003 17.1 11.9 0.003 17.1 8.2 4.0 4 0 0 4 4 4 2 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 KLO16760.1 - 5.1 7.2 14.8 1.2 9.2 3.8 2.8 2 0 0 2 2 2 0 RING-H2 zinc finger DUF2408 PF10303.4 KLO16761.1 - 0.54 10.3 2.6 1.4 9.0 1.6 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2408) Kelch_6 PF13964.1 KLO16762.1 - 1.3e-19 69.4 0.7 2.2e-05 24.4 0.0 4.8 4 0 0 4 4 4 4 Kelch motif Kelch_4 PF13418.1 KLO16762.1 - 4.2e-19 68.0 8.4 6.8e-06 25.7 0.1 5.0 5 0 0 5 5 5 4 Galactose oxidase, central domain Kelch_2 PF07646.10 KLO16762.1 - 3e-17 61.6 3.4 4.9e-05 22.9 0.0 5.9 6 0 0 6 6 6 3 Kelch motif Kelch_5 PF13854.1 KLO16762.1 - 9.5e-17 60.5 0.5 2.4e-05 24.1 0.0 4.4 4 0 0 4 4 4 3 Kelch motif Kelch_3 PF13415.1 KLO16762.1 - 7.6e-16 57.7 4.6 2.3e-06 27.5 0.0 5.6 5 0 0 5 5 5 3 Galactose oxidase, central domain Kelch_1 PF01344.20 KLO16762.1 - 4.9e-14 51.5 0.4 0.0059 16.1 0.0 4.3 4 0 0 4 4 4 3 Kelch motif FMO-like PF00743.14 KLO16763.1 - 2.2e-25 88.8 0.2 7.1e-24 83.8 0.1 2.3 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 KLO16763.1 - 1.2e-23 84.2 0.0 3.2e-23 82.8 0.0 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 KLO16763.1 - 5.3e-11 42.0 0.3 4.4e-09 35.7 0.0 2.7 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 KLO16763.1 - 5.6e-10 39.4 0.0 8.7e-08 32.2 0.0 2.2 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.15 KLO16763.1 - 3e-05 24.1 0.1 0.086 12.9 0.0 2.4 2 0 0 2 2 2 2 Shikimate / quinate 5-dehydrogenase Pyr_redox PF00070.22 KLO16763.1 - 5.9e-05 23.3 1.1 0.035 14.4 0.0 2.7 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 KLO16763.1 - 0.002 17.9 0.1 0.16 11.7 0.0 2.5 2 0 0 2 2 2 1 FAD-NAD(P)-binding TrkA_N PF02254.13 KLO16763.1 - 0.0083 16.1 0.2 0.039 13.9 0.0 2.2 3 0 0 3 3 2 1 TrkA-N domain 2-Hacid_dh_C PF02826.14 KLO16763.1 - 0.014 14.5 0.0 0.26 10.4 0.0 2.4 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DAO PF01266.19 KLO16763.1 - 0.016 14.1 0.3 1 8.1 0.0 3.1 3 1 0 3 3 3 0 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KLO16763.1 - 0.021 14.8 0.0 0.072 13.1 0.0 1.9 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.9 KLO16763.1 - 0.071 11.5 0.3 0.24 9.8 0.0 1.8 2 0 0 2 2 2 0 HI0933-like protein NAD_binding_7 PF13241.1 KLO16763.1 - 0.073 13.3 0.0 20 5.4 0.0 2.4 2 0 0 2 2 2 0 Putative NAD(P)-binding CPSase_L_chain PF00289.17 KLO16763.1 - 0.079 13.0 0.2 0.52 10.4 0.0 2.1 2 0 0 2 2 2 0 Carbamoyl-phosphate synthase L chain, N-terminal domain SnoaL_2 PF12680.2 KLO16763.1 - 0.082 13.3 0.2 0.94 9.9 0.1 2.5 2 0 0 2 2 2 0 SnoaL-like domain FMO-like PF00743.14 KLO16764.1 - 9.2e-25 86.8 0.2 8.5e-19 67.1 0.0 2.7 2 1 1 3 3 3 2 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 KLO16764.1 - 2.6e-24 86.4 0.1 2.8e-23 83.0 0.0 2.4 3 0 0 3 3 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 KLO16764.1 - 2.9e-12 46.8 0.0 2.8e-09 37.1 0.0 2.2 1 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 KLO16764.1 - 8.7e-10 38.0 0.1 3.9e-06 26.0 0.0 3.0 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Shikimate_DH PF01488.15 KLO16764.1 - 9.1e-07 29.0 0.1 0.002 18.2 0.0 2.4 2 0 0 2 2 2 2 Shikimate / quinate 5-dehydrogenase NAD_binding_9 PF13454.1 KLO16764.1 - 4.7e-06 26.4 0.3 0.0029 17.3 0.0 2.7 3 0 0 3 3 2 1 FAD-NAD(P)-binding 2-Hacid_dh_C PF02826.14 KLO16764.1 - 0.00013 21.2 0.0 0.06 12.4 0.0 2.3 2 0 0 2 2 2 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Lycopene_cycl PF05834.7 KLO16764.1 - 0.00022 20.3 0.5 0.00087 18.3 0.0 2.3 3 0 0 3 3 3 1 Lycopene cyclase protein FAD_binding_2 PF00890.19 KLO16764.1 - 0.00033 19.6 0.3 0.00061 18.7 0.2 1.4 1 0 0 1 1 1 1 FAD binding domain GIDA PF01134.17 KLO16764.1 - 0.00043 19.2 0.2 0.021 13.7 0.0 2.3 2 0 0 2 2 2 1 Glucose inhibited division protein A TrkA_N PF02254.13 KLO16764.1 - 0.00049 20.0 0.0 0.078 12.9 0.0 2.4 2 0 0 2 2 2 1 TrkA-N domain FAD_binding_3 PF01494.14 KLO16764.1 - 0.00093 18.3 0.0 0.0045 16.0 0.0 2.0 2 0 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.1 KLO16764.1 - 0.001 19.0 0.0 0.0038 17.2 0.0 2.0 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 KLO16764.1 - 0.001 19.3 0.0 0.95 9.9 0.0 3.3 3 1 0 3 3 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 KLO16764.1 - 0.0013 17.2 0.5 0.0058 15.1 0.0 1.9 2 0 0 2 2 2 1 HI0933-like protein DAO PF01266.19 KLO16764.1 - 0.0018 17.2 2.3 0.021 13.7 0.1 2.7 3 1 0 3 3 3 1 FAD dependent oxidoreductase Thi4 PF01946.12 KLO16764.1 - 0.0059 15.7 0.1 0.013 14.5 0.0 1.5 1 0 0 1 1 1 1 Thi4 family NAD_binding_7 PF13241.1 KLO16764.1 - 0.018 15.2 0.0 1.7 8.9 0.0 2.3 2 0 0 2 2 2 0 Putative NAD(P)-binding Amino_oxidase PF01593.19 KLO16764.1 - 0.02 13.9 0.1 5.6 5.9 0.0 2.2 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase CPSase_L_chain PF00289.17 KLO16764.1 - 0.029 14.4 0.1 2 8.5 0.0 2.5 2 0 0 2 2 2 0 Carbamoyl-phosphate synthase L chain, N-terminal domain KR PF08659.5 KLO16764.1 - 0.049 13.2 0.0 0.2 11.3 0.0 1.9 2 0 0 2 2 2 0 KR domain SnoaL_2 PF12680.2 KLO16764.1 - 0.096 13.1 0.7 0.37 11.2 0.0 2.3 2 0 0 2 2 2 0 SnoaL-like domain FAD_oxidored PF12831.2 KLO16764.1 - 0.11 11.5 0.4 0.17 10.9 0.3 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase Aldolase_II PF00596.16 KLO16765.1 - 9.5e-42 142.6 0.0 1.2e-41 142.3 0.0 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain Thaumatin PF00314.12 KLO16766.1 - 0.018 14.5 2.1 0.37 10.2 0.7 2.1 1 1 0 1 1 1 0 Thaumatin family Pkinase PF00069.20 KLO16769.1 - 4.3e-69 232.5 0.0 1.1e-68 231.1 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 KLO16769.1 - 5.9e-39 133.6 0.0 1.1e-37 129.5 0.0 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 KLO16769.1 - 1.9e-08 33.6 0.0 6.2e-08 31.9 0.0 1.7 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 KLO16769.1 - 0.02 13.9 0.0 0.031 13.3 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.4 KLO16769.1 - 0.06 12.6 0.0 0.11 11.8 0.0 1.4 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL APH PF01636.18 KLO16769.1 - 0.15 11.7 0.0 0.63 9.7 0.0 1.9 1 1 1 2 2 2 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 KLO16769.1 - 0.19 10.5 0.0 0.3 9.8 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 FolB PF02152.13 KLO16770.1 - 4.2e-31 107.4 0.1 3.3e-14 52.9 0.0 2.2 2 0 0 2 2 2 2 Dihydroneopterin aldolase Glyco_transf_90 PF05686.7 KLO16771.1 - 8e-19 67.5 2.1 7.4e-18 64.4 0.1 2.9 3 0 0 3 3 3 1 Glycosyl transferase family 90 DUF1311 PF07007.7 KLO16771.1 - 0.1 12.6 0.1 0.38 10.8 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1311) Asp PF00026.18 KLO16772.1 - 4.2e-47 160.9 13.1 7.7e-47 160.0 9.1 1.4 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 KLO16772.1 - 4.7e-07 29.9 4.9 8.3e-06 25.8 2.2 2.9 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 KLO16772.1 - 9.8e-05 22.7 5.4 0.053 14.0 0.7 3.0 3 0 0 3 3 3 2 Aspartyl protease gag-asp_proteas PF13975.1 KLO16772.1 - 0.099 12.4 0.4 2.6 7.9 0.0 2.5 2 0 0 2 2 2 0 gag-polyprotein putative aspartyl protease Glyco_transf_90 PF05686.7 KLO16773.1 - 3.7e-22 78.5 1.8 1.2e-21 76.8 0.1 2.3 3 0 0 3 3 3 1 Glycosyl transferase family 90 Pkinase PF00069.20 KLO16774.1 - 1.2e-55 188.5 0.0 1.6e-55 188.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KLO16774.1 - 2e-32 112.2 0.0 2.8e-32 111.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KLO16774.1 - 2.4e-10 39.8 0.0 1.1e-07 31.1 0.0 2.2 2 0 0 2 2 2 2 Kinase-like RIO1 PF01163.17 KLO16774.1 - 0.012 14.9 0.1 0.031 13.6 0.0 1.6 2 0 0 2 2 2 0 RIO1 family Kdo PF06293.9 KLO16774.1 - 0.044 12.8 0.0 0.076 12.0 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.6 KLO16774.1 - 0.092 11.5 0.0 0.18 10.5 0.0 1.4 1 0 0 1 1 1 0 Seadornavirus VP7 Pkinase PF00069.20 KLO16775.1 - 2.6e-46 157.9 0.0 3.3e-46 157.5 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KLO16775.1 - 1.2e-42 145.8 0.0 1.6e-42 145.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KLO16775.1 - 3.8e-05 22.7 0.0 5.3e-05 22.3 0.0 1.2 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.17 KLO16775.1 - 0.011 15.0 0.2 0.025 13.9 0.1 1.5 1 0 0 1 1 1 0 RIO1 family APH PF01636.18 KLO16775.1 - 0.067 12.9 0.0 0.4 10.3 0.0 1.9 1 1 1 2 2 2 0 Phosphotransferase enzyme family Proteasom_Rpn13 PF04683.8 KLO16778.1 - 1.1e-23 83.1 0.0 1.9e-23 82.3 0.0 1.3 1 0 0 1 1 1 1 Proteasome complex subunit Rpn13 ubiquitin receptor DUF2205 PF10224.4 KLO16779.1 - 7.4e-12 44.6 0.4 8.4e-12 44.4 0.2 1.1 1 0 0 1 1 1 1 Predicted coiled-coil protein (DUF2205) DUF964 PF06133.6 KLO16779.1 - 0.0017 18.3 1.1 0.029 14.3 0.1 2.0 1 1 1 2 2 2 1 Protein of unknown function (DUF964) Peptidase_M10_C PF08548.6 KLO16779.1 - 0.021 14.4 0.2 0.021 14.3 0.1 1.1 1 0 0 1 1 1 0 Peptidase M10 serralysin C terminal DUF3450 PF11932.3 KLO16779.1 - 0.042 13.1 0.2 0.044 13.0 0.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) Erp_C PF06780.6 KLO16779.1 - 0.042 13.6 1.0 0.062 13.1 0.7 1.3 1 1 0 1 1 1 0 Erp protein C-terminus Mod_r PF07200.8 KLO16779.1 - 0.078 12.9 0.4 0.086 12.7 0.3 1.1 1 0 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein FlxA PF14282.1 KLO16779.1 - 0.083 12.8 0.7 0.095 12.6 0.5 1.1 1 0 0 1 1 1 0 FlxA-like protein DUF972 PF06156.8 KLO16779.1 - 0.099 13.0 0.6 0.11 12.8 0.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF972) Orbi_NS3 PF01616.11 KLO16779.1 - 0.15 10.9 1.2 0.14 11.1 0.5 1.4 1 1 0 1 1 1 0 Orbivirus NS3 Pet127 PF08634.5 KLO16780.1 - 4.4e-95 317.9 0.1 9.3e-95 316.8 0.1 1.5 2 0 0 2 2 2 1 Mitochondrial protein Pet127 Peptidase_M3 PF01432.15 KLO16781.1 - 2.4e-129 432.3 0.0 3.3e-129 431.8 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M3 Peptidase_M50B PF13398.1 KLO16781.1 - 0.024 14.0 0.3 0.042 13.2 0.2 1.3 1 0 0 1 1 1 0 Peptidase M50B-like Usp PF00582.21 KLO16782.1 - 2.4e-18 66.6 0.2 2.4e-18 66.6 0.1 3.1 3 0 0 3 3 3 1 Universal stress protein family TPR_12 PF13424.1 KLO16783.1 - 4.9e-48 160.9 19.9 5.2e-09 35.9 0.6 9.3 4 2 5 10 10 10 10 Tetratricopeptide repeat TPR_10 PF13374.1 KLO16783.1 - 3.7e-40 134.7 20.9 6.7e-05 22.6 0.0 13.3 13 0 0 13 13 13 8 Tetratricopeptide repeat TPR_2 PF07719.12 KLO16783.1 - 3.3e-17 60.9 15.3 0.0096 15.7 0.1 10.9 11 0 0 11 11 10 4 Tetratricopeptide repeat TPR_11 PF13414.1 KLO16783.1 - 1.4e-15 56.6 21.3 0.0012 18.4 1.5 8.1 4 2 5 9 9 9 6 TPR repeat Apc5 PF12862.2 KLO16783.1 - 3.3e-11 42.8 30.3 0.15 11.9 0.0 11.8 2 1 9 12 12 12 3 Anaphase-promoting complex subunit 5 TPR_8 PF13181.1 KLO16783.1 - 1.8e-10 39.8 20.2 1.5 8.7 0.1 11.0 12 0 0 12 12 12 3 Tetratricopeptide repeat TPR_1 PF00515.23 KLO16783.1 - 1.7e-05 24.2 13.5 0.038 13.6 0.1 7.3 9 0 0 9 9 9 1 Tetratricopeptide repeat DUF3856 PF12968.2 KLO16783.1 - 0.00021 21.1 11.3 0.11 12.3 0.0 5.4 1 1 5 7 7 7 2 Domain of Unknown Function (DUF3856) TPR_16 PF13432.1 KLO16783.1 - 0.00048 20.7 24.3 0.61 10.8 0.2 8.5 5 3 3 9 9 9 2 Tetratricopeptide repeat TPR_17 PF13431.1 KLO16783.1 - 0.0013 18.7 11.1 0.88 9.9 0.0 7.1 7 0 0 7 7 7 1 Tetratricopeptide repeat SHNi-TPR PF10516.4 KLO16783.1 - 0.0072 15.5 6.3 0.028 13.6 0.0 4.2 5 0 0 5 5 5 1 SHNi-TPR AAA_19 PF13245.1 KLO16783.1 - 0.0096 15.6 0.0 0.029 14.1 0.0 1.8 1 0 0 1 1 1 1 Part of AAA domain NACHT PF05729.7 KLO16783.1 - 0.01 15.5 0.0 0.023 14.3 0.0 1.6 1 0 0 1 1 1 1 NACHT domain TRP_2 PF08344.6 KLO16783.1 - 0.024 14.5 3.3 1 9.3 0.0 4.4 5 0 0 5 5 4 0 Transient receptor ion channel II AAA_17 PF13207.1 KLO16783.1 - 0.093 13.5 0.1 4.6 8.0 0.0 3.3 3 0 0 3 3 2 0 AAA domain Cren7 PF11520.3 KLO16783.1 - 0.31 10.6 0.0 0.68 9.6 0.0 1.4 1 0 0 1 1 1 0 Chromatin protein Cren7 TPR_6 PF13174.1 KLO16783.1 - 2.7 8.6 6.0 59 4.4 0.0 4.7 5 0 0 5 5 2 0 Tetratricopeptide repeat Sas10_Utp3 PF04000.10 KLO16783.1 - 4.8 7.4 10.8 0.13 12.4 0.5 3.6 3 0 0 3 3 2 0 Sas10/Utp3/C1D family TPR_7 PF13176.1 KLO16783.1 - 5.6 7.0 12.5 45 4.2 0.0 6.9 8 0 0 8 8 8 0 Tetratricopeptide repeat GPI-anchored PF10342.4 KLO16785.1 - 1.6e-05 25.2 0.0 8.1e-05 23.0 0.0 1.9 1 1 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family RXT2_N PF08595.6 KLO16786.1 - 0.048 13.4 2.7 0.075 12.8 1.9 1.3 1 0 0 1 1 1 0 RXT2-like, N-terminal Sigma70_ner PF04546.8 KLO16786.1 - 0.08 12.5 4.0 0.16 11.5 2.8 1.6 1 0 0 1 1 1 0 Sigma-70, non-essential region Myc_N PF01056.13 KLO16786.1 - 0.081 12.0 1.6 0.12 11.5 1.1 1.2 1 0 0 1 1 1 0 Myc amino-terminal region NOA36 PF06524.7 KLO16786.1 - 0.12 11.6 4.8 0.16 11.1 3.3 1.2 1 0 0 1 1 1 0 NOA36 protein Nucleoplasmin PF03066.10 KLO16786.1 - 0.13 11.7 4.3 0.21 11.0 2.9 1.3 1 0 0 1 1 1 0 Nucleoplasmin Daxx PF03344.10 KLO16786.1 - 0.21 10.0 3.4 0.27 9.6 2.3 1.1 1 0 0 1 1 1 0 Daxx Family DUF2457 PF10446.4 KLO16786.1 - 0.93 8.1 9.9 1.3 7.7 6.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) PBP1_TM PF14812.1 KLO16786.1 - 1.3 9.3 7.7 3.3 8.0 5.3 1.7 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal FAM176 PF14851.1 KLO16786.1 - 1.4 8.6 4.2 2.7 7.6 2.9 1.5 1 0 0 1 1 1 0 FAM176 family CENP-B_dimeris PF09026.5 KLO16786.1 - 2.6 8.3 10.5 5.6 7.2 7.3 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain DUF4611 PF15387.1 KLO16786.1 - 3.2 7.9 9.7 21 5.3 6.7 2.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4611) AAA_23 PF13476.1 KLO16787.1 - 3e-25 89.7 0.0 3e-25 89.7 0.0 7.8 1 1 2 3 3 1 1 AAA domain AAA_21 PF13304.1 KLO16787.1 - 6.4e-14 52.6 5.5 8.8e-08 32.4 0.1 3.7 3 1 0 3 3 3 2 AAA domain AAA_13 PF13166.1 KLO16787.1 - 1.6e-10 40.1 113.1 1.6e-05 23.6 0.0 6.5 3 2 2 6 6 5 4 AAA domain SbcCD_C PF13558.1 KLO16787.1 - 2e-10 40.4 0.0 7.1e-10 38.6 0.0 2.0 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit SMC_N PF02463.14 KLO16787.1 - 8.8e-10 38.1 0.1 8.8e-10 38.1 0.0 2.6 2 1 0 2 2 1 1 RecF/RecN/SMC N terminal domain AAA_15 PF13175.1 KLO16787.1 - 3.1e-05 23.2 12.7 3.1e-05 23.2 8.8 4.7 2 2 2 4 4 2 2 AAA ATPase domain AAA_29 PF13555.1 KLO16787.1 - 0.00055 19.4 0.0 0.0014 18.1 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain Methyltransf_17 PF12692.2 KLO16787.1 - 0.0013 18.4 0.3 1.8 8.2 0.0 2.9 2 0 0 2 2 2 2 S-adenosyl-L-methionine methyltransferase Sec8_exocyst PF04048.9 KLO16787.1 - 0.0044 16.6 1.8 0.0044 16.6 1.3 7.6 6 3 1 7 7 7 1 Sec8 exocyst complex component specific domain IFT57 PF10498.4 KLO16787.1 - 0.0089 14.8 102.2 0.14 10.8 1.5 6.8 3 2 2 6 6 6 5 Intra-flagellar transport protein 57 DUF3584 PF12128.3 KLO16787.1 - 0.021 12.1 122.6 0.16 9.2 18.8 6.2 2 1 3 6 6 6 0 Protein of unknown function (DUF3584) AAA_19 PF13245.1 KLO16787.1 - 0.073 12.8 0.3 0.34 10.7 0.0 2.2 2 0 0 2 2 2 0 Part of AAA domain Reo_sigmaC PF04582.7 KLO16787.1 - 3.7 6.6 40.7 0.25 10.4 0.5 6.4 4 2 3 7 7 7 0 Reovirus sigma C capsid protein ECH PF00378.15 KLO16788.1 - 3.1e-74 249.2 1.3 3.9e-74 248.8 0.9 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family Peptidase_S49 PF01343.13 KLO16788.1 - 0.00027 20.7 0.6 0.0066 16.2 0.1 2.4 2 0 0 2 2 2 1 Peptidase family S49 AMP-binding PF00501.23 KLO16789.1 - 1e-82 277.7 0.0 2.2e-82 276.7 0.0 1.6 1 0 0 1 1 1 1 AMP-binding enzyme DER1 PF04511.10 KLO16790.1 - 8.2e-47 159.2 8.4 9.9e-47 158.9 5.8 1.0 1 0 0 1 1 1 1 Der1-like family Mmp37 PF09139.6 KLO16791.1 - 1.4e-103 346.3 0.0 1.8e-103 346.0 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial matrix Mmp37 EB1_binding PF05937.6 KLO16791.1 - 0.016 15.5 6.7 0.032 14.6 4.6 1.4 1 0 0 1 1 1 0 EB-1 Binding Domain adh_short PF00106.20 KLO16792.1 - 1.2e-29 103.3 0.0 3.9e-29 101.7 0.0 1.7 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 KLO16792.1 - 3.5e-10 39.8 0.0 7.4e-10 38.7 0.0 1.6 2 0 0 2 2 2 1 KR domain adh_short_C2 PF13561.1 KLO16792.1 - 4e-09 36.5 0.0 4.9e-09 36.2 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF1776 PF08643.5 KLO16792.1 - 0.00033 19.8 0.0 0.00043 19.5 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) Epimerase PF01370.16 KLO16792.1 - 0.00051 19.5 0.1 0.0016 17.9 0.0 1.9 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 KLO16792.1 - 0.002 17.1 0.0 0.0029 16.5 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Eno-Rase_NADH_b PF12242.3 KLO16792.1 - 0.0037 17.0 2.5 0.01 15.6 1.8 1.7 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase NmrA PF05368.8 KLO16792.1 - 0.0084 15.3 0.0 0.059 12.6 0.0 2.0 2 0 0 2 2 2 1 NmrA-like family NAD_binding_10 PF13460.1 KLO16792.1 - 0.066 13.2 0.1 0.12 12.3 0.1 1.7 1 1 0 1 1 1 0 NADH(P)-binding SET PF00856.23 KLO16793.1 - 3.1e-10 40.5 0.0 6.7e-10 39.4 0.0 1.6 1 0 0 1 1 1 1 SET domain zf-MYND PF01753.13 KLO16794.1 - 0.001 18.9 7.8 0.0017 18.2 5.4 1.3 1 0 0 1 1 1 1 MYND finger NDK PF00334.14 KLO16795.1 - 7.9e-18 64.5 0.0 1.3e-17 63.8 0.0 1.3 1 0 0 1 1 1 1 Nucleoside diphosphate kinase MAD PF05557.8 KLO16795.1 - 0.055 11.5 0.0 0.078 11.0 0.0 1.1 1 0 0 1 1 1 0 Mitotic checkpoint protein DUF3143 PF11341.3 KLO16798.1 - 0.13 12.1 0.0 0.23 11.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3143) DPBB_1 PF03330.13 KLO16799.1 - 2.2e-07 30.7 0.3 3.5e-07 30.1 0.2 1.4 1 1 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Barwin PF00967.12 KLO16799.1 - 0.00012 21.7 0.3 0.00016 21.3 0.2 1.3 1 1 0 1 1 1 1 Barwin family Cerato-platanin PF07249.7 KLO16799.1 - 0.061 13.3 0.1 0.094 12.7 0.1 1.3 1 1 0 1 1 1 0 Cerato-platanin Peptidase_M3 PF01432.15 KLO16802.1 - 5.4e-129 431.1 0.0 7.2e-129 430.7 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M3 Peptidase_M50B PF13398.1 KLO16802.1 - 0.014 14.7 0.2 0.025 13.9 0.2 1.3 1 0 0 1 1 1 0 Peptidase M50B-like Alg6_Alg8 PF03155.10 KLO16804.1 - 1.1e-135 453.1 16.1 3e-135 451.6 11.1 1.6 1 1 0 1 1 1 1 ALG6, ALG8 glycosyltransferase family 4HBT PF03061.17 KLO16805.1 - 3.2e-14 52.8 0.1 4.3e-14 52.3 0.1 1.2 1 0 0 1 1 1 1 Thioesterase superfamily 4HBT_3 PF13622.1 KLO16805.1 - 0.0033 17.2 0.0 0.0036 17.0 0.0 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily DUF4442 PF14539.1 KLO16805.1 - 0.0084 16.0 0.0 0.013 15.5 0.0 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF4442) Pkinase PF00069.20 KLO16806.1 - 7.7e-71 238.2 0.0 1.7e-70 237.1 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KLO16806.1 - 7.8e-51 172.6 0.0 3.6e-50 170.4 0.0 1.9 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 KLO16806.1 - 0.00034 19.6 0.0 0.0016 17.5 0.0 2.0 2 0 0 2 2 2 1 Kinase-like RTTN_N PF14726.1 KLO16806.1 - 0.21 12.1 1.6 3.5 8.2 0.0 3.0 2 1 1 3 3 3 0 Rotatin, an armadillo repeat protein, centriole functioning Phage_int_SAM_1 PF02899.12 KLO16810.1 - 0.002 18.2 0.1 0.0056 16.8 0.0 1.7 1 1 0 1 1 1 1 Phage integrase, N-terminal SAM-like domain Phage_int_SAM_4 PF13495.1 KLO16810.1 - 0.0069 16.6 0.0 0.016 15.5 0.0 1.6 1 1 0 1 1 1 1 Phage integrase, N-terminal SAM-like domain CENP-F_leu_zip PF10473.4 KLO16811.1 - 0.87 9.4 5.5 0.39 10.5 2.3 1.5 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Filament PF00038.16 KLO16813.1 - 0.029 13.8 5.6 0.039 13.4 3.7 1.3 1 1 0 1 1 1 0 Intermediate filament protein GIDA PF01134.17 KLO16813.1 - 0.077 11.8 0.3 0.1 11.4 0.2 1.1 1 0 0 1 1 1 0 Glucose inhibited division protein A Atg14 PF10186.4 KLO16813.1 - 0.18 10.7 1.9 0.2 10.5 1.3 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 CDC48_2 PF02933.12 KLO16814.1 - 5.6e-07 29.1 0.0 6.6e-07 28.8 0.0 1.1 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), domain 2 Neisseria_TspB PF05616.8 KLO16815.1 - 4.8 5.4 5.5 7.1 4.8 3.8 1.1 1 0 0 1 1 1 0 Neisseria meningitidis TspB protein Phage_integrase PF00589.17 KLO16817.1 - 1.2e-05 25.0 0.0 1.5e-05 24.7 0.0 1.2 1 0 0 1 1 1 1 Phage integrase family MFS_1 PF07690.11 KLO16819.1 - 9.2e-39 133.1 40.5 9.2e-39 133.1 28.1 1.9 2 0 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 KLO16819.1 - 5.8e-16 57.8 15.9 1.1e-15 56.9 11.0 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 KLO16819.1 - 1.1e-15 57.1 7.9 1.1e-15 57.1 5.5 2.4 2 0 0 2 2 2 2 Sugar (and other) transporter HlyIII PF03006.15 KLO16819.1 - 7.1 5.9 22.1 6.5 6.0 11.1 3.4 2 1 1 3 3 3 0 Haemolysin-III related Acetyltransf_3 PF13302.1 KLO16820.1 - 0.078 13.1 0.0 0.11 12.6 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Ribosomal_S10 PF00338.17 KLO16825.1 - 2.8e-21 75.1 0.0 7.9e-21 73.7 0.0 1.7 2 0 0 2 2 2 1 Ribosomal protein S10p/S20e DGF-1_C PF11040.3 KLO16828.1 - 3 7.8 17.1 78 3.2 0.1 6.0 1 1 6 7 7 7 0 Dispersed gene family protein 1 of Trypanosoma cruzi C-terminus LamB_YcsF PF03746.11 KLO16829.1 - 2.3e-70 236.4 0.0 2.6e-70 236.2 0.0 1.0 1 0 0 1 1 1 1 LamB/YcsF family Hydrophobin PF01185.13 KLO16830.1 - 1.6e-22 79.7 11.7 1.7e-22 79.6 8.1 1.0 1 0 0 1 1 1 1 Fungal hydrophobin Diacid_rec PF05651.8 KLO16830.1 - 0.0056 16.0 0.1 0.0064 15.9 0.1 1.2 1 0 0 1 1 1 1 Putative sugar diacid recognition EnY2 PF10163.4 KLO16832.1 - 2.6e-19 68.9 0.0 2.9e-19 68.7 0.0 1.0 1 0 0 1 1 1 1 Transcription factor e(y)2 RecO_C PF02565.10 KLO16832.1 - 0.033 14.0 0.0 0.038 13.8 0.0 1.0 1 0 0 1 1 1 0 Recombination protein O C terminal DUF1479 PF07350.7 KLO16832.1 - 0.11 10.9 0.0 0.13 10.7 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1479) AtpR PF12966.2 KLO16834.1 - 2 8.6 8.1 3.1 7.9 0.1 3.0 3 0 0 3 3 3 0 N-ATPase, AtpR subunit DUF2975 PF11188.3 KLO16835.1 - 1.8 8.3 6.5 2.5 7.8 4.0 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF2975) DUF3098 PF11297.3 KLO16836.1 - 0.00064 19.3 4.7 0.0029 17.2 0.8 3.2 3 0 0 3 3 3 1 Protein of unknown function (DUF3098) F-box-like PF12937.2 KLO16837.1 - 0.0081 15.8 1.6 0.038 13.7 0.1 3.0 2 1 1 3 3 3 1 F-box-like CPSase_L_D2 PF02786.12 KLO16838.1 - 9.7e-115 381.1 0.2 7.7e-83 276.9 0.0 2.3 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_sm_chain PF00988.17 KLO16838.1 - 3.6e-47 159.1 0.0 1.3e-46 157.3 0.0 2.0 2 0 0 2 2 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain OTCace_N PF02729.16 KLO16838.1 - 2.5e-45 153.6 0.0 5.2e-45 152.5 0.0 1.6 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain GATase PF00117.23 KLO16838.1 - 3.2e-42 144.1 0.0 7.8e-42 142.8 0.0 1.7 2 0 0 2 2 2 1 Glutamine amidotransferase class-I CPSase_L_D3 PF02787.14 KLO16838.1 - 1.3e-41 141.2 0.2 3e-41 140.0 0.1 1.7 1 0 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain CPSase_L_chain PF00289.17 KLO16838.1 - 4.1e-41 139.5 0.0 1.8e-19 69.8 0.0 2.7 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, N-terminal domain OTCace PF00185.19 KLO16838.1 - 4.2e-36 124.2 0.1 1.1e-35 122.8 0.0 1.8 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain ATP-grasp_4 PF13535.1 KLO16838.1 - 1.2e-34 119.6 0.0 4.8e-21 75.3 0.0 2.5 2 0 0 2 2 2 2 ATP-grasp domain ATPgrasp_Ter PF15632.1 KLO16838.1 - 6.4e-23 81.0 0.2 4.1e-10 38.9 0.0 4.1 3 1 0 3 3 3 3 ATP-grasp in the biosynthetic pathway with Ter operon MGS PF02142.17 KLO16838.1 - 3.3e-19 68.6 0.0 2.6e-18 65.7 0.0 2.7 3 0 0 3 3 1 1 MGS-like domain Dala_Dala_lig_C PF07478.8 KLO16838.1 - 2.5e-16 59.6 0.2 1.2e-08 34.6 0.0 2.6 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus ATP-grasp PF02222.17 KLO16838.1 - 8.9e-16 57.7 0.0 6.1e-08 32.2 0.0 2.4 2 0 0 2 2 2 2 ATP-grasp domain ATP-grasp_3 PF02655.9 KLO16838.1 - 1.9e-05 24.5 0.1 0.072 12.9 0.0 2.6 2 0 0 2 2 2 2 ATP-grasp domain Peptidase_C26 PF07722.8 KLO16838.1 - 5.8e-05 22.6 0.1 0.002 17.6 0.1 2.6 1 1 0 1 1 1 1 Peptidase C26 Hydrolase PF00702.21 KLO16838.1 - 0.041 14.2 0.1 8.1 6.7 0.0 3.0 2 1 1 3 3 3 0 haloacid dehalogenase-like hydrolase DAHP_synth_1 PF00793.15 KLO16838.1 - 0.13 10.9 0.0 0.26 9.9 0.0 1.4 1 0 0 1 1 1 0 DAHP synthetase I family Jag_N PF14804.1 KLO16838.1 - 1.1 9.3 4.1 49 4.0 0.0 3.6 3 0 0 3 3 3 0 Jag N-terminus zf-MYND PF01753.13 KLO16839.1 - 1e-11 44.4 12.8 1.5e-11 43.9 8.9 1.3 1 0 0 1 1 1 1 MYND finger zf-Mss51 PF13824.1 KLO16839.1 - 0.00012 21.8 7.0 0.0002 21.1 4.9 1.3 1 0 0 1 1 1 1 Zinc-finger of mitochondrial splicing suppressor 51 zf-NADH-PPase PF09297.6 KLO16839.1 - 0.042 13.3 2.4 0.57 9.7 0.1 2.4 2 0 0 2 2 2 0 NADH pyrophosphatase zinc ribbon domain Herpes_BLRF2 PF05812.7 KLO16839.1 - 0.043 13.6 0.1 0.069 12.9 0.1 1.2 1 0 0 1 1 1 0 Herpesvirus BLRF2 protein zf-HIT PF04438.11 KLO16839.1 - 0.7 9.5 7.7 1.3 8.7 5.3 1.3 1 0 0 1 1 1 0 HIT zinc finger p450 PF00067.17 KLO16841.1 - 1.2e-70 238.4 0.1 2.9e-70 237.0 0.1 1.5 1 1 0 1 1 1 1 Cytochrome P450 Tubulin PF00091.20 KLO16842.1 - 2.7e-69 233.2 0.0 5.2e-69 232.3 0.0 1.4 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 KLO16842.1 - 1.5e-48 164.0 0.3 2.4e-48 163.3 0.2 1.4 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.4 KLO16842.1 - 1.6e-06 28.1 0.0 4.4e-06 26.7 0.0 1.8 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.1 KLO16842.1 - 0.057 12.8 0.0 0.11 11.9 0.0 1.5 1 0 0 1 1 1 0 Tubulin domain dsrm PF00035.20 KLO16843.1 - 4.6e-10 39.9 0.0 2.7e-09 37.4 0.0 1.9 2 0 0 2 2 2 1 Double-stranded RNA binding motif Pkinase PF00069.20 KLO16844.1 - 4.7e-33 114.4 0.0 6.6e-33 113.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KLO16844.1 - 1.3e-32 112.8 0.0 1.8e-32 112.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KLO16844.1 - 0.00029 19.8 0.0 0.00045 19.2 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 KLO16844.1 - 0.01 15.5 0.0 0.024 14.3 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family ABC1 PF03109.11 KLO16844.1 - 0.099 12.6 0.0 0.17 11.8 0.0 1.3 1 0 0 1 1 1 0 ABC1 family Pkinase PF00069.20 KLO16845.1 - 2e-35 122.1 0.0 3.1e-35 121.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KLO16845.1 - 1.6e-33 115.8 0.0 2.4e-33 115.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 KLO16845.1 - 0.0076 16.0 0.0 0.017 14.8 0.0 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family WaaY PF06176.6 KLO16845.1 - 0.025 13.7 0.0 0.039 13.1 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide core biosynthesis protein (WaaY) Seadorna_VP7 PF07387.6 KLO16845.1 - 0.027 13.3 0.0 0.039 12.7 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Kdo PF06293.9 KLO16845.1 - 0.058 12.4 0.0 0.096 11.7 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family adh_short PF00106.20 KLO16846.1 - 9.5e-34 116.7 0.0 1.3e-33 116.3 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KLO16846.1 - 2.2e-13 50.5 0.0 2.6e-13 50.3 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KLO16846.1 - 2.4e-13 50.1 0.0 3.5e-13 49.6 0.0 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 KLO16846.1 - 6.9e-05 22.3 0.1 0.00036 20.0 0.1 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 KLO16846.1 - 0.022 14.7 0.0 0.084 12.8 0.0 1.9 1 1 0 1 1 1 0 NADH(P)-binding 2-Hacid_dh_C PF02826.14 KLO16846.1 - 0.023 13.8 0.0 0.034 13.3 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain zf-H2C2_2 PF13465.1 KLO16847.1 - 1.1e-09 38.1 2.5 1.2e-07 31.6 0.1 3.3 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2 PF00096.21 KLO16847.1 - 1.2e-06 28.4 11.8 5.4e-06 26.4 0.3 4.1 4 1 0 4 4 4 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KLO16847.1 - 8e-06 25.8 7.2 0.0013 18.9 0.2 3.5 3 0 0 3 3 3 2 C2H2-type zinc finger zf-Di19 PF05605.7 KLO16847.1 - 0.0016 18.5 2.6 0.065 13.3 0.3 2.4 1 1 1 2 2 2 1 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_6 PF13912.1 KLO16847.1 - 0.073 12.9 3.4 0.78 9.7 0.0 3.1 3 0 0 3 3 3 0 C2H2-type zinc finger Herpes_capsid PF06112.6 KLO16847.1 - 0.12 12.4 2.8 0.35 10.9 1.9 1.8 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein zf-C2H2_jaz PF12171.3 KLO16847.1 - 0.16 12.1 1.3 0.3 11.2 0.0 2.2 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 KLO16847.1 - 0.76 10.0 3.2 0.98 9.7 0.0 2.6 3 0 0 3 3 3 0 Zinc-finger of C2H2 type TPR_11 PF13414.1 KLO16848.1 - 1.2e-16 60.0 9.9 0.0004 19.9 0.0 6.5 6 2 2 8 8 8 6 TPR repeat TPR_14 PF13428.1 KLO16848.1 - 2.3e-11 43.2 14.7 0.41 11.4 0.3 8.3 5 2 2 7 7 7 6 Tetratricopeptide repeat TPR_19 PF14559.1 KLO16848.1 - 3.3e-11 43.3 10.8 0.27 11.6 0.1 6.3 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_16 PF13432.1 KLO16848.1 - 7.1e-11 42.4 15.3 0.027 15.1 0.0 6.6 6 1 0 6 6 6 3 Tetratricopeptide repeat TPR_2 PF07719.12 KLO16848.1 - 1.3e-09 37.2 17.4 0.22 11.5 0.1 8.7 9 0 0 9 9 9 3 Tetratricopeptide repeat TPR_1 PF00515.23 KLO16848.1 - 3.6e-09 35.8 1.0 0.19 11.4 0.0 7.2 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_12 PF13424.1 KLO16848.1 - 1.3e-07 31.4 8.6 0.042 13.8 0.0 6.0 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_8 PF13181.1 KLO16848.1 - 6.8e-07 28.6 0.0 0.43 10.4 0.0 4.9 6 1 0 6 6 5 2 Tetratricopeptide repeat TPR_17 PF13431.1 KLO16848.1 - 2.9e-06 27.0 0.6 0.54 10.5 0.0 5.7 7 0 0 7 7 5 1 Tetratricopeptide repeat Apc3 PF12895.2 KLO16848.1 - 0.00071 19.6 5.3 0.5 10.5 0.6 5.0 5 1 0 6 6 5 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.1 KLO16848.1 - 0.0088 15.7 3.3 15 5.6 0.0 5.5 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_9 PF13371.1 KLO16848.1 - 0.14 12.0 0.1 0.14 12.0 0.1 3.8 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_4 PF07721.9 KLO16848.1 - 0.28 11.7 12.9 1.7 9.2 0.0 5.7 5 0 0 5 5 5 0 Tetratricopeptide repeat Alginate_lyase PF05426.7 KLO16850.1 - 1.6e-53 181.8 0.5 2e-53 181.4 0.3 1.1 1 0 0 1 1 1 1 Alginate lyase TAFII28 PF04719.9 KLO16851.1 - 5.9e-28 96.5 0.0 7e-28 96.2 0.0 1.1 1 0 0 1 1 1 1 hTAFII28-like protein conserved region CBFD_NFYB_HMF PF00808.18 KLO16851.1 - 0.0084 16.1 0.0 0.012 15.6 0.0 1.3 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Ly49 PF08391.5 KLO16853.1 - 0.21 11.7 1.3 0.33 11.0 0.2 1.8 2 0 0 2 2 2 0 Ly49-like protein, N-terminal region DUF368 PF04018.8 KLO16853.1 - 0.65 9.1 7.5 0.35 10.0 3.7 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF368) Wzy_C PF04932.10 KLO16853.1 - 1.5 8.5 7.9 3.8 7.2 5.5 1.7 1 1 0 1 1 1 0 O-Antigen ligase DUF3433 PF11915.3 KLO16854.1 - 2.9e-19 68.9 2.9 2.9e-19 68.9 2.0 2.4 3 0 0 3 3 3 1 Protein of unknown function (DUF3433) MerC PF03203.9 KLO16854.1 - 0.51 10.7 7.9 0.23 11.8 0.1 2.9 4 0 0 4 4 4 0 MerC mercury resistance protein FmrO PF07091.6 KLO16856.1 - 0.0053 15.7 0.0 0.0086 15.0 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA methyltransferase (FmrO) Borrelia_lipo_1 PF05714.6 KLO16857.1 - 0.022 13.8 0.5 0.039 13.0 0.4 1.3 1 0 0 1 1 1 0 Borrelia burgdorferi virulent strain associated lipoprotein zf-CSL PF05207.8 KLO16859.1 - 2.2e-24 84.7 0.9 5.9e-24 83.3 0.6 1.8 1 0 0 1 1 1 1 CSL zinc finger Zn-ribbon_8 PF09723.5 KLO16859.1 - 0.061 13.2 1.5 0.12 12.3 1.0 1.4 1 0 0 1 1 1 0 Zinc ribbon domain zinc_ribbon_5 PF13719.1 KLO16859.1 - 0.095 12.3 0.5 0.16 11.5 0.3 1.4 1 0 0 1 1 1 0 zinc-ribbon domain Nop14 PF04147.7 KLO16859.1 - 0.31 8.9 16.2 0.3 8.9 11.2 1.0 1 0 0 1 1 1 0 Nop14-like family Paf1 PF03985.8 KLO16859.1 - 0.44 9.2 11.5 0.62 8.7 8.0 1.2 1 0 0 1 1 1 0 Paf1 SDA1 PF05285.7 KLO16859.1 - 0.45 9.7 12.7 0.4 9.9 8.8 1.1 1 0 0 1 1 1 0 SDA1 CobT PF06213.7 KLO16859.1 - 0.66 9.0 14.5 0.75 8.8 10.1 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Sigma70_ner PF04546.8 KLO16859.1 - 0.71 9.4 10.9 1 8.9 7.5 1.4 1 0 0 1 1 1 0 Sigma-70, non-essential region Daxx PF03344.10 KLO16859.1 - 0.77 8.1 13.6 0.8 8.1 9.4 1.1 1 0 0 1 1 1 0 Daxx Family CDC45 PF02724.9 KLO16859.1 - 1.1 7.1 12.9 1.3 6.9 9.0 1.0 1 0 0 1 1 1 0 CDC45-like protein BUD22 PF09073.5 KLO16859.1 - 2.5 7.0 12.9 2.8 6.9 8.9 1.1 1 0 0 1 1 1 0 BUD22 DUF1510 PF07423.6 KLO16859.1 - 6.6 6.0 12.5 8.6 5.6 8.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) DUF21 PF01595.15 KLO16860.1 - 2.3e-25 88.9 0.7 3.8e-25 88.2 0.5 1.3 1 0 0 1 1 1 1 Domain of unknown function DUF21 CBS PF00571.23 KLO16860.1 - 0.00013 21.6 1.5 0.058 13.1 0.1 3.4 3 0 0 3 3 3 2 CBS domain Proteasome PF00227.21 KLO16861.1 - 3.6e-27 94.9 0.0 4.2e-27 94.6 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Alpha_GJ PF03229.8 KLO16863.1 - 0.073 13.4 0.6 0.1 12.9 0.4 1.1 1 0 0 1 1 1 0 Alphavirus glycoprotein J p450 PF00067.17 KLO16864.1 - 1.2e-52 178.9 1.1 1.1e-51 175.8 0.8 1.9 1 1 0 1 1 1 1 Cytochrome P450 Kdo PF06293.9 KLO16865.1 - 5.5e-12 45.1 0.0 5.5e-10 38.6 0.0 2.3 2 1 1 3 3 3 2 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KLO16865.1 - 2.3e-06 27.5 0.0 1.1e-05 25.2 0.0 1.8 1 1 1 2 2 2 1 Phosphotransferase enzyme family Pkinase PF00069.20 KLO16865.1 - 3.5e-05 23.0 0.0 5.6e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain RIO1 PF01163.17 KLO16865.1 - 0.0001 21.7 0.0 0.016 14.5 0.0 2.2 1 1 0 1 1 1 1 RIO1 family EcKinase PF02958.15 KLO16865.1 - 0.00021 20.5 0.2 0.00062 18.9 0.0 1.9 2 1 0 2 2 2 1 Ecdysteroid kinase Pkinase_Tyr PF07714.12 KLO16865.1 - 0.021 13.9 0.0 0.027 13.5 0.0 1.2 1 0 0 1 1 1 0 Protein tyrosine kinase UPF0172 PF03665.8 KLO16866.1 - 1.6e-43 148.5 0.0 1.9e-43 148.2 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0172) JAB PF01398.16 KLO16866.1 - 0.16 11.7 0.0 0.26 11.0 0.0 1.3 1 0 0 1 1 1 0 JAB1/Mov34/MPN/PAD-1 ubiquitin protease GFO_IDH_MocA PF01408.17 KLO16868.1 - 1.1e-23 84.0 0.0 1.9e-23 83.2 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold Semialdhyde_dh PF01118.19 KLO16868.1 - 0.0032 17.7 0.0 0.0057 16.9 0.0 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain DXP_reductoisom PF02670.11 KLO16868.1 - 0.024 15.1 0.0 0.081 13.4 0.0 1.8 2 0 0 2 2 2 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase GFO_IDH_MocA_C PF02894.12 KLO16868.1 - 0.06 13.1 0.0 0.14 11.9 0.0 1.7 1 0 0 1 1 1 0 Oxidoreductase family, C-terminal alpha/beta domain DUF218 PF02698.12 KLO16868.1 - 0.15 11.5 0.0 0.31 10.5 0.0 1.4 1 0 0 1 1 1 0 DUF218 domain Carn_acyltransf PF00755.15 KLO16869.1 - 2.7e-160 534.3 0.0 3.5e-160 533.9 0.0 1.1 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase ASXH PF13919.1 KLO16870.1 - 6.5e-18 64.8 0.4 2.4e-17 63.0 0.3 1.9 1 1 0 1 1 1 1 Asx homology domain DUF2992 PF11208.3 KLO16870.1 - 6.3 6.7 8.7 0.88 9.4 3.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2992) Redoxin PF08534.5 KLO16871.1 - 8.6e-28 96.7 0.2 1e-27 96.4 0.1 1.1 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.16 KLO16871.1 - 3.7e-11 42.8 0.0 4.4e-11 42.5 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_8 PF13905.1 KLO16871.1 - 0.021 14.9 0.0 0.031 14.3 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin-like zf-C2H2_4 PF13894.1 KLO16873.1 - 0.013 15.7 9.1 1.6 9.2 2.7 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger GFO_IDH_MocA PF01408.17 KLO16878.1 - 4.2e-22 78.9 0.0 6.6e-22 78.2 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 KLO16878.1 - 9.3e-06 25.4 0.0 2.9e-05 23.8 0.0 1.8 2 0 0 2 2 2 1 Oxidoreductase family, C-terminal alpha/beta domain DXP_reductoisom PF02670.11 KLO16878.1 - 0.0098 16.4 0.0 0.022 15.2 0.0 1.5 1 0 0 1 1 1 1 1-deoxy-D-xylulose 5-phosphate reductoisomerase Semialdhyde_dh PF01118.19 KLO16878.1 - 0.012 15.8 0.0 0.025 14.8 0.0 1.5 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Chromate_transp PF02417.10 KLO16879.1 - 0.0024 17.4 9.3 0.15 11.6 2.0 2.3 2 0 0 2 2 2 2 Chromate transporter FHA PF00498.21 KLO16880.1 - 0.0022 18.0 0.0 0.005 16.9 0.0 1.6 1 0 0 1 1 1 1 FHA domain SKG6 PF08693.5 KLO16881.1 - 8.4e-05 21.8 0.2 8.4e-05 21.8 0.2 2.4 2 0 0 2 2 2 1 Transmembrane alpha-helix domain Lactamase_B_2 PF12706.2 KLO16882.1 - 9.4e-42 142.7 0.3 1.2e-41 142.3 0.2 1.2 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 KLO16882.1 - 2.1e-13 50.3 0.0 6.4e-13 48.7 0.0 1.8 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 KLO16882.1 - 0.22 11.1 6.7 1.9 8.0 4.6 2.4 1 1 0 1 1 1 0 Metallo-beta-lactamase superfamily DUF2500 PF10694.4 KLO16883.1 - 0.085 12.8 0.5 0.12 12.3 0.1 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2500) zf-4CXXC_R1 PF10497.4 KLO16884.1 - 3.3e-08 33.6 13.9 6.6e-08 32.6 9.6 1.5 1 0 0 1 1 1 1 Zinc-finger domain of monoamine-oxidase A repressor R1 MMR_HSR1 PF01926.18 KLO16885.1 - 3.9e-20 71.9 0.0 1.3e-14 54.0 0.0 2.3 2 0 0 2 2 2 2 50S ribosome-binding GTPase FeoB_N PF02421.13 KLO16885.1 - 2e-06 27.1 0.0 0.00011 21.5 0.0 2.3 2 0 0 2 2 2 1 Ferrous iron transport protein B GTP_EFTU PF00009.22 KLO16885.1 - 1.3e-05 24.7 0.0 0.0019 17.6 0.0 2.7 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain Miro PF08477.8 KLO16885.1 - 0.00025 21.5 0.0 0.25 11.8 0.0 2.6 2 0 0 2 2 2 2 Miro-like protein Dynamin_N PF00350.18 KLO16885.1 - 0.00052 19.8 0.2 0.21 11.3 0.1 2.7 2 1 1 3 3 3 1 Dynamin family DUF258 PF03193.11 KLO16885.1 - 0.0032 16.6 0.0 0.0066 15.6 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_16 PF13191.1 KLO16885.1 - 0.017 15.1 1.3 2.2 8.2 0.0 2.5 2 1 0 2 2 2 0 AAA ATPase domain AIG1 PF04548.11 KLO16885.1 - 0.029 13.4 0.0 0.06 12.4 0.0 1.5 1 0 0 1 1 1 0 AIG1 family MobB PF03205.9 KLO16885.1 - 0.036 13.7 0.0 0.071 12.8 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_17 PF13207.1 KLO16885.1 - 0.055 14.2 0.0 3.1 8.6 0.0 2.3 2 0 0 2 2 2 0 AAA domain ArgK PF03308.11 KLO16885.1 - 0.067 11.9 0.1 0.16 10.7 0.0 1.6 1 0 0 1 1 1 0 ArgK protein cobW PF02492.14 KLO16885.1 - 0.097 12.1 0.0 2.4 7.5 0.0 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain PduV-EutP PF10662.4 KLO16885.1 - 0.11 11.9 0.0 6.3 6.2 0.0 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Glyco_hydro_16 PF00722.16 KLO16886.1 - 2e-18 66.3 0.2 2.5e-17 62.7 0.0 2.2 1 1 1 2 2 2 1 Glycosyl hydrolases family 16 SPR1 PF15356.1 KLO16886.1 - 0.023 15.0 1.8 4.7 7.5 0.1 2.5 2 0 0 2 2 2 0 Psoriasis susceptibility locus 2 Glyco_trans_2_3 PF13632.1 KLO16887.1 - 9.8e-53 178.7 0.3 9.8e-53 178.7 0.2 2.0 3 0 0 3 3 3 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 KLO16887.1 - 1.7e-10 41.1 0.4 1.2e-09 38.2 0.0 2.4 3 0 0 3 3 3 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.21 KLO16887.1 - 0.0064 16.1 0.0 0.045 13.4 0.0 2.2 2 0 0 2 2 2 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.1 KLO16887.1 - 0.0067 15.7 0.2 0.02 14.1 0.0 1.8 2 0 0 2 2 2 1 Glycosyl transferase family 21 F-box-like PF12937.2 KLO16888.1 - 2.9e-05 23.6 0.1 9.7e-05 22.0 0.0 2.0 2 0 0 2 2 2 1 F-box-like DUF2859 PF11072.3 KLO16888.1 - 0.036 13.5 0.0 0.07 12.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2859) DUF607 PF04678.8 KLO16889.1 - 1.3e-38 132.7 0.0 2.2e-38 131.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF607 p450 PF00067.17 KLO16890.1 - 3.6e-07 29.0 0.0 4e-07 28.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 KLO16891.1 - 1.7e-47 162.0 0.0 7.4e-47 159.9 0.0 1.7 1 1 0 1 1 1 1 Cytochrome P450 Zn_clus PF00172.13 KLO16893.1 - 8.2e-10 38.4 6.1 9.8e-10 38.1 4.2 1.1 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain NinF PF05810.7 KLO16893.1 - 0.1 12.4 1.1 0.12 12.1 0.8 1.3 1 0 0 1 1 1 0 NinF protein RRN7 PF11781.3 KLO16893.1 - 1.3 8.6 5.7 4.1 6.9 4.0 1.8 1 1 0 1 1 1 0 RNA polymerase I-specific transcription initiation factor Rrn7 DUF3716 PF12511.3 KLO16893.1 - 1.5 8.5 6.9 76 3.0 4.8 2.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3716) Bax1-I PF01027.15 KLO16894.1 - 1.7e-43 148.6 19.6 2e-43 148.4 13.6 1.0 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 DUF4229 PF14012.1 KLO16894.1 - 2.3 8.2 8.5 0.34 10.8 2.4 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF4229) MDM31_MDM32 PF08118.6 KLO16895.1 - 5.9e-142 473.6 0.1 7.2e-142 473.3 0.1 1.1 1 0 0 1 1 1 1 Yeast mitochondrial distribution and morphology (MDM) proteins DUF2242 PF10001.4 KLO16895.1 - 0.14 12.0 0.2 0.33 10.8 0.1 1.7 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2242) CMAS PF02353.15 KLO16896.1 - 1.8e-36 125.6 0.1 2.3e-36 125.3 0.1 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_31 PF13847.1 KLO16896.1 - 1.2e-16 60.6 0.0 2.4e-16 59.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KLO16896.1 - 1.1e-11 45.3 0.0 2.5e-11 44.1 0.0 1.6 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KLO16896.1 - 2.5e-11 43.5 0.0 4.1e-11 42.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KLO16896.1 - 3.8e-11 43.3 0.0 1.3e-10 41.6 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.9 KLO16896.1 - 2e-10 40.3 0.0 3.4e-10 39.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_12 PF08242.7 KLO16896.1 - 9.9e-10 38.7 0.0 3.2e-09 37.1 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KLO16896.1 - 1.8e-07 31.4 0.0 5e-07 30.0 0.0 1.8 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 KLO16896.1 - 1.6e-06 27.3 0.0 3.1e-06 26.3 0.0 1.4 1 0 0 1 1 1 1 Putative methyltransferase MetW PF07021.7 KLO16896.1 - 3.6e-05 23.2 0.0 0.00015 21.1 0.0 2.0 1 1 0 1 1 1 1 Methionine biosynthesis protein MetW TehB PF03848.9 KLO16896.1 - 0.00066 18.8 0.0 0.0012 18.0 0.0 1.3 1 0 0 1 1 1 1 Tellurite resistance protein TehB Methyltransf_26 PF13659.1 KLO16896.1 - 0.0008 19.4 0.0 0.0017 18.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain GidB PF02527.10 KLO16896.1 - 0.00082 18.5 0.0 0.0013 17.8 0.0 1.2 1 0 0 1 1 1 1 rRNA small subunit methyltransferase G PCMT PF01135.14 KLO16896.1 - 0.00084 18.9 0.0 0.0012 18.3 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) RrnaAD PF00398.15 KLO16896.1 - 0.0014 17.7 0.0 0.0025 16.9 0.0 1.3 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase DUF938 PF06080.7 KLO16896.1 - 0.0068 15.9 0.0 0.012 15.1 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF938) Methyltransf_32 PF13679.1 KLO16896.1 - 0.026 14.2 0.0 0.045 13.4 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain tRNA_U5-meth_tr PF05958.6 KLO16896.1 - 0.045 12.4 0.0 0.059 12.0 0.0 1.2 1 0 0 1 1 1 0 tRNA (Uracil-5-)-methyltransferase MmgE_PrpD PF03972.9 KLO16897.1 - 6.6e-162 538.7 0.0 7.7e-162 538.4 0.0 1.0 1 0 0 1 1 1 1 MmgE/PrpD family GFA PF04828.9 KLO16898.1 - 4.5e-23 81.0 0.2 5.9e-23 80.6 0.1 1.2 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme zf-Dof PF02701.10 KLO16898.1 - 0.067 13.1 0.5 7.6 6.5 0.0 2.3 2 0 0 2 2 2 0 Dof domain, zinc finger zf-ribbon_3 PF13248.1 KLO16898.1 - 0.072 12.3 4.0 0.28 10.4 0.0 2.9 2 1 1 3 3 3 0 zinc-ribbon domain DZR PF12773.2 KLO16898.1 - 0.11 12.3 3.1 0.51 10.2 0.0 2.3 2 0 0 2 2 2 0 Double zinc ribbon Auto_anti-p27 PF06677.7 KLO16898.1 - 0.24 11.1 0.0 0.24 11.1 0.0 2.5 3 0 0 3 3 3 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) GFA PF04828.9 KLO16899.1 - 1e-19 70.2 1.9 1.4e-19 69.8 1.3 1.2 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme NinF PF05810.7 KLO16899.1 - 0.15 11.8 0.0 0.15 11.8 0.0 2.0 2 0 0 2 2 2 0 NinF protein Slu7 PF11708.3 KLO16901.1 - 6.9e-83 278.0 10.5 6.9e-83 278.0 7.3 1.8 2 0 0 2 2 2 1 Pre-mRNA splicing Prp18-interacting factor zf-CCHC_4 PF14392.1 KLO16901.1 - 0.15 11.7 1.9 0.3 10.7 1.3 1.5 1 0 0 1 1 1 0 Zinc knuckle RNase_H2-Ydr279 PF09468.5 KLO16903.1 - 9.5e-44 149.8 0.1 1.2e-43 149.5 0.0 1.0 1 0 0 1 1 1 1 Ydr279p protein family (RNase H2 complex component) IF-2B PF01008.12 KLO16904.1 - 1.2e-63 214.7 0.0 1.4e-63 214.5 0.0 1.1 1 0 0 1 1 1 1 Initiation factor 2 subunit family AAA_28 PF13521.1 KLO16904.1 - 0.1 12.5 0.0 0.16 11.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain CMAS PF02353.15 KLO16907.1 - 3.8e-25 88.4 0.1 6.7e-25 87.6 0.0 1.4 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_18 PF12847.2 KLO16907.1 - 3.5e-09 37.2 0.0 1.6e-08 35.0 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 KLO16907.1 - 6.6e-09 35.5 0.0 1.2e-08 34.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KLO16907.1 - 6.5e-08 32.1 0.0 1.2e-07 31.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_4 PF02390.12 KLO16907.1 - 6.7e-07 28.5 0.0 1.2e-06 27.7 0.0 1.4 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_23 PF13489.1 KLO16907.1 - 1.8e-05 24.5 0.0 9.6e-05 22.1 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KLO16907.1 - 3.5e-05 24.2 0.0 0.0001 22.7 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KLO16907.1 - 4.4e-05 23.8 0.0 0.00018 21.9 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KLO16907.1 - 0.00038 20.7 0.0 0.00074 19.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain tRNA_U5-meth_tr PF05958.6 KLO16907.1 - 0.00048 18.9 0.0 0.00064 18.5 0.0 1.2 1 0 0 1 1 1 1 tRNA (Uracil-5-)-methyltransferase GidB PF02527.10 KLO16907.1 - 0.016 14.3 0.0 0.03 13.4 0.0 1.4 1 0 0 1 1 1 0 rRNA small subunit methyltransferase G TehB PF03848.9 KLO16907.1 - 0.022 13.9 0.0 0.051 12.7 0.0 1.6 2 0 0 2 2 2 0 Tellurite resistance protein TehB DUF938 PF06080.7 KLO16907.1 - 0.027 14.0 0.0 0.046 13.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF938) PCMT PF01135.14 KLO16907.1 - 0.04 13.4 0.0 0.061 12.8 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) RrnaAD PF00398.15 KLO16907.1 - 0.045 12.7 0.0 0.066 12.2 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Methyltransf_32 PF13679.1 KLO16907.1 - 0.053 13.1 0.0 0.1 12.2 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain FtsJ PF01728.14 KLO16907.1 - 0.091 12.7 0.0 0.14 12.1 0.0 1.4 1 0 0 1 1 1 0 FtsJ-like methyltransferase LON PF02190.11 KLO16907.1 - 0.14 11.8 0.0 0.29 10.7 0.0 1.3 1 1 0 1 1 1 0 ATP-dependent protease La (LON) domain F-box-like PF12937.2 KLO16910.1 - 5e-05 22.9 0.2 0.00022 20.9 0.1 2.2 1 0 0 1 1 1 1 F-box-like F-box-like_2 PF13013.1 KLO16910.1 - 0.012 15.3 0.0 3.8 7.2 0.0 3.3 3 0 0 3 3 3 0 F-box-like domain F-box-like PF12937.2 KLO16911.1 - 7.4e-05 22.3 0.3 0.00024 20.7 0.2 2.0 1 0 0 1 1 1 1 F-box-like F-box-like PF12937.2 KLO16912.1 - 7.9e-07 28.7 1.0 3.7e-06 26.5 0.1 2.7 4 0 0 4 4 4 1 F-box-like Pkinase PF00069.20 KLO16914.1 - 1.4e-38 132.5 0.0 3.1e-24 85.5 0.0 3.2 3 0 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.12 KLO16914.1 - 1.3e-17 63.6 0.0 3.1e-17 62.5 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase IncA PF04156.9 KLO16914.1 - 0.087 12.4 6.3 0.15 11.6 4.4 1.3 1 0 0 1 1 1 0 IncA protein Sugarporin_N PF11471.3 KLO16914.1 - 0.27 10.9 10.3 0.75 9.4 7.2 1.7 1 0 0 1 1 1 0 Maltoporin periplasmic N-terminal extension Mnd1 PF03962.10 KLO16914.1 - 3.6 7.1 6.1 6.2 6.4 4.2 1.2 1 0 0 1 1 1 0 Mnd1 family F-box-like PF12937.2 KLO16915.1 - 2.4e-05 23.9 0.0 8.9e-05 22.1 0.0 2.1 1 0 0 1 1 1 1 F-box-like p450 PF00067.17 KLO16916.1 - 1.3e-68 231.6 0.0 1.6e-68 231.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 MnhB PF04039.8 KLO16916.1 - 0.074 13.1 0.0 0.15 12.1 0.0 1.4 1 0 0 1 1 1 0 Domain related to MnhB subunit of Na+/H+ antiporter AATase PF07247.7 KLO16917.1 - 5.2e-35 120.9 0.0 6.6e-35 120.5 0.0 1.1 1 0 0 1 1 1 1 Alcohol acetyltransferase Condensation PF00668.15 KLO16917.1 - 2.4e-08 33.1 0.0 0.00015 20.7 0.0 2.3 2 0 0 2 2 2 2 Condensation domain U3_assoc_6 PF08640.6 KLO16918.1 - 2.2e-26 91.4 0.2 9.4e-26 89.3 0.2 2.1 2 0 0 2 2 2 1 U3 small nucleolar RNA-associated protein 6 TPR_14 PF13428.1 KLO16918.1 - 0.00082 19.8 0.4 2.8 8.8 0.0 4.2 1 1 2 3 3 3 1 Tetratricopeptide repeat NRDE-2 PF08424.5 KLO16918.1 - 0.009 14.9 4.4 0.058 12.2 0.2 3.3 3 1 0 3 3 3 1 NRDE-2, necessary for RNA interference DUF1572 PF07609.6 KLO16918.1 - 0.044 13.3 0.2 0.09 12.3 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1572) TPR_17 PF13431.1 KLO16918.1 - 0.064 13.4 0.0 44 4.6 0.0 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat XkdW PF09636.5 KLO16918.1 - 0.073 12.9 0.2 3 7.7 0.1 2.9 2 0 0 2 2 2 0 XkdW protein O-FucT PF10250.4 KLO16919.1 - 0.00043 19.5 0.2 0.73 8.8 0.0 2.1 2 0 0 2 2 2 2 GDP-fucose protein O-fucosyltransferase Aldedh PF00171.17 KLO16920.1 - 1.4e-79 267.6 0.0 1.6e-79 267.3 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family ACT_7 PF13840.1 KLO16920.1 - 0.0051 16.3 0.0 0.015 14.7 0.0 1.8 1 0 0 1 1 1 1 ACT domain Cwf_Cwc_15 PF04889.7 KLO16923.1 - 0.15 11.7 5.7 0.2 11.3 4.0 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Nop14 PF04147.7 KLO16923.1 - 0.27 9.1 11.0 0.35 8.7 7.6 1.1 1 0 0 1 1 1 0 Nop14-like family DUF2457 PF10446.4 KLO16923.1 - 0.28 9.8 10.2 0.49 9.0 7.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) MFS_1 PF07690.11 KLO16924.1 - 1e-17 63.9 33.3 1e-17 63.9 23.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Pox_VERT_large PF04441.8 KLO16924.1 - 0.48 8.5 1.3 0.69 8.0 0.9 1.1 1 0 0 1 1 1 0 Poxvirus early transcription factor (VETF), large subunit Got1 PF04178.7 KLO16925.1 - 3.2e-20 72.4 12.8 3.6e-20 72.2 8.9 1.0 1 0 0 1 1 1 1 Got1/Sft2-like family DUF973 PF06157.6 KLO16925.1 - 5.3 5.9 10.6 9.2 5.1 7.3 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF973) DUF3185 PF11381.3 KLO16925.1 - 7.7 6.3 11.3 7.5 6.4 0.3 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3185) Aldo_ket_red PF00248.16 KLO16931.1 - 1.1e-51 175.3 0.0 1.2e-51 175.1 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Aldo_ket_red PF00248.16 KLO16932.1 - 6.5e-34 117.0 0.0 9.7e-34 116.4 0.0 1.3 1 1 0 1 1 1 1 Aldo/keto reductase family Aldo_ket_red PF00248.16 KLO16933.1 - 7.8e-49 165.9 0.0 8.7e-49 165.8 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family USP8_interact PF08941.5 KLO16934.1 - 0.11 11.7 0.1 0.18 11.1 0.1 1.2 1 0 0 1 1 1 0 USP8 interacting RskA PF10099.4 KLO16938.1 - 0.035 13.8 0.5 0.057 13.1 0.3 1.2 1 0 0 1 1 1 0 Anti-sigma-K factor rskA HSP70 PF00012.15 KLO16941.1 - 2.8e-152 507.7 0.1 2.8e-152 507.7 0.1 1.4 2 0 0 2 2 2 1 Hsp70 protein MreB_Mbl PF06723.8 KLO16941.1 - 6.6e-10 38.1 0.3 2e-09 36.5 0.0 1.8 2 0 0 2 2 2 1 MreB/Mbl protein DRIM PF07539.7 KLO16941.1 - 0.034 13.5 0.0 0.072 12.4 0.0 1.4 1 0 0 1 1 1 0 Down-regulated in metastasis WD40 PF00400.27 KLO16942.1 - 1.5 8.8 7.0 4.3 7.3 0.1 4.4 4 0 0 4 4 4 0 WD domain, G-beta repeat IBR PF01485.16 KLO16943.1 - 1.4e-15 56.9 27.5 1.1e-09 38.0 11.0 4.0 3 1 1 4 4 4 2 IBR domain zf-C3HC4 PF00097.20 KLO16943.1 - 7.9e-05 22.2 8.3 7.9e-05 22.2 5.8 4.4 3 1 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KLO16943.1 - 0.00027 20.8 10.8 0.00027 20.8 7.5 4.1 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KLO16943.1 - 3.6 7.4 39.3 0.042 13.6 6.6 3.5 3 0 0 3 3 3 0 Ring finger domain tRNA-synt_2 PF00152.15 KLO16944.1 - 9.9e-90 300.6 0.0 1.4e-89 300.2 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 KLO16944.1 - 5.1e-11 42.2 0.1 2.4e-10 40.1 0.0 2.1 2 0 0 2 2 2 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.15 KLO16944.1 - 1.3e-08 34.3 0.1 0.00017 20.8 0.0 2.7 3 0 0 3 3 3 2 tRNA synthetases class II core domain (F) Glyco_tranf_2_3 PF13641.1 KLO16945.1 - 1.2e-24 87.3 0.0 1.9e-24 86.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.21 KLO16945.1 - 7.1e-12 45.3 0.0 1.1e-11 44.6 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.1 KLO16945.1 - 4.2e-07 29.4 0.1 1.4e-06 27.7 0.0 1.8 1 1 0 1 1 1 1 Glycosyl transferase family 21 Glyco_trans_2_3 PF13632.1 KLO16945.1 - 2.4e-06 27.4 9.5 5.5e-06 26.2 6.6 1.7 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Chitin_synth_2 PF03142.10 KLO16945.1 - 0.12 10.6 2.9 0.8 8.0 2.0 1.9 1 1 0 1 1 1 0 Chitin synthase Use1 PF09753.4 KLO16946.1 - 4.4e-17 62.3 3.3 2.8e-16 59.7 2.3 2.0 1 1 0 1 1 1 1 Membrane fusion protein Use1 DUF948 PF06103.6 KLO16946.1 - 0.34 10.7 1.6 1 9.2 0.2 2.2 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) DASH_Dad4 PF08650.5 KLO16948.1 - 3.1e-19 68.6 0.2 3.4e-19 68.5 0.1 1.0 1 0 0 1 1 1 1 DASH complex subunit Dad4 DASH_Dad1 PF08649.5 KLO16948.1 - 0.0015 18.2 0.1 0.0017 17.9 0.0 1.2 1 0 0 1 1 1 1 DASH complex subunit Dad1 DUF3683 PF12447.3 KLO16948.1 - 0.0085 15.9 0.7 0.01 15.6 0.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3683) MCPsignal PF00015.16 KLO16948.1 - 0.028 13.9 0.1 0.028 13.9 0.0 1.0 1 0 0 1 1 1 0 Methyl-accepting chemotaxis protein (MCP) signalling domain Dor1 PF04124.7 KLO16948.1 - 0.053 11.9 0.2 0.063 11.7 0.2 1.0 1 0 0 1 1 1 0 Dor1-like family GATase_5 PF13507.1 KLO16949.1 - 2e-97 325.1 0.0 3.1e-97 324.5 0.0 1.3 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain AIRS_C PF02769.17 KLO16949.1 - 2e-45 154.5 0.1 1.3e-24 86.9 0.0 2.3 2 0 0 2 2 2 2 AIR synthase related protein, C-terminal domain AIRS PF00586.19 KLO16949.1 - 1.1e-23 83.3 0.6 4.7e-23 81.2 0.0 2.5 3 0 0 3 3 3 1 AIR synthase related protein, N-terminal domain R3H PF01424.17 KLO16950.1 - 0.09 12.4 0.2 0.32 10.7 0.0 2.0 2 0 0 2 2 2 0 R3H domain Chitin_synth_1 PF01644.12 KLO16951.1 - 8.5e-81 269.5 0.0 1.3e-80 268.9 0.0 1.3 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_2 PF03142.10 KLO16951.1 - 5.7e-26 91.0 0.8 6.9e-20 70.9 0.0 2.2 2 0 0 2 2 2 2 Chitin synthase Chitin_synth_1N PF08407.6 KLO16951.1 - 5.4e-24 83.6 0.2 1.9e-23 81.9 0.1 2.0 1 0 0 1 1 1 1 Chitin synthase N-terminal Glyco_trans_2_3 PF13632.1 KLO16951.1 - 1.2e-11 44.7 2.3 5.2e-11 42.6 1.6 2.2 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 KLO16951.1 - 2.6e-07 30.6 0.0 7.3e-07 29.2 0.0 1.7 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Pkinase PF00069.20 KLO16952.1 - 9.1e-35 120.0 0.0 1.1e-34 119.7 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KLO16952.1 - 1.5e-33 115.9 0.0 1.9e-33 115.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase UDPGT PF00201.13 KLO16953.1 - 4.4e-19 68.3 0.0 6.6e-19 67.8 0.0 1.1 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_trans_1_3 PF13528.1 KLO16953.1 - 0.076 12.1 0.0 0.13 11.3 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase family 1 ubiquitin PF00240.18 KLO16954.1 - 1.7e-10 40.0 0.0 5.9e-10 38.4 0.0 1.9 2 0 0 2 2 2 1 Ubiquitin family BAG PF02179.11 KLO16954.1 - 2.1e-10 40.5 0.0 3.3e-10 39.9 0.0 1.3 1 0 0 1 1 1 1 BAG domain Ubiquitin_2 PF14560.1 KLO16954.1 - 0.00067 19.8 0.0 0.0056 16.9 0.0 2.3 2 1 0 2 2 2 1 Ubiquitin-like domain Pkinase PF00069.20 KLO16955.1 - 2.5e-53 180.9 0.0 3e-53 180.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KLO16955.1 - 9.2e-38 129.7 0.0 1.3e-37 129.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KLO16955.1 - 4.5e-07 29.1 0.0 6.9e-07 28.5 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 KLO16955.1 - 0.042 13.5 0.0 0.1 12.2 0.0 1.7 2 0 0 2 2 2 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 KLO16955.1 - 0.11 11.3 0.0 0.18 10.5 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 Exo_endo_phos PF03372.18 KLO16956.1 - 5.4e-12 46.1 0.0 8.5e-12 45.5 0.0 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Asparaginase_2 PF01112.13 KLO16957.1 - 6.2e-46 156.5 1.0 8e-46 156.2 0.7 1.1 1 0 0 1 1 1 1 Asparaginase DJ-1_PfpI PF01965.19 KLO16957.1 - 0.1 12.0 0.0 0.17 11.3 0.0 1.4 1 0 0 1 1 1 0 DJ-1/PfpI family tRNA-synt_1 PF00133.17 KLO16958.1 - 4.5e-205 682.1 0.1 2.2e-204 679.9 0.0 1.9 2 0 0 2 2 2 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.8 KLO16958.1 - 2.5e-27 95.4 0.6 7.5e-27 93.9 0.1 2.0 2 0 0 2 2 2 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.6 KLO16958.1 - 1.2e-17 63.6 0.5 1.3e-05 24.0 0.0 4.2 4 0 0 4 4 4 4 tRNA synthetases class I (M) tRNA-synt_1e PF01406.14 KLO16958.1 - 0.00082 18.5 0.0 0.0019 17.3 0.0 1.6 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain FAD_binding_3 PF01494.14 KLO16959.1 - 1.3e-20 73.7 0.0 4.6e-20 71.9 0.0 1.7 1 1 0 1 1 1 1 FAD binding domain SE PF08491.5 KLO16959.1 - 0.0016 17.3 0.0 0.0027 16.5 0.0 1.3 1 0 0 1 1 1 1 Squalene epoxidase NAD_binding_8 PF13450.1 KLO16959.1 - 0.0019 18.1 0.1 0.0058 16.6 0.0 1.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 KLO16959.1 - 0.0047 15.8 0.3 0.18 10.7 0.1 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase Trp_halogenase PF04820.9 KLO16959.1 - 0.0074 14.9 1.0 0.045 12.3 0.1 2.4 3 0 0 3 3 3 1 Tryptophan halogenase Pyr_redox PF00070.22 KLO16959.1 - 0.044 14.1 0.2 0.62 10.5 0.1 2.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 KLO16959.1 - 0.055 13.2 0.2 0.97 9.1 0.0 2.2 2 0 0 2 2 2 0 FAD-NAD(P)-binding tRNA-synt_1 PF00133.17 KLO16960.1 - 6.4e-215 714.6 0.1 2e-214 713.0 0.0 1.7 2 0 0 2 2 2 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.8 KLO16960.1 - 8.9e-25 87.2 0.3 3.4e-24 85.3 0.0 2.0 2 0 0 2 2 2 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.6 KLO16960.1 - 1.4e-19 70.0 1.0 4.4e-06 25.6 0.0 4.2 3 1 0 4 4 4 4 tRNA synthetases class I (M) tRNA-synt_1e PF01406.14 KLO16960.1 - 0.0013 17.8 0.0 0.0048 16.0 0.0 1.9 2 0 0 2 2 2 1 tRNA synthetases class I (C) catalytic domain DEAD PF00270.24 KLO16961.1 - 1e-34 119.4 0.0 2.1e-34 118.4 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF4217 PF13959.1 KLO16961.1 - 6e-19 67.3 0.2 1.1e-18 66.4 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) Helicase_C PF00271.26 KLO16961.1 - 1.8e-15 56.5 0.0 4.2e-15 55.3 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 KLO16961.1 - 0.00073 19.4 0.0 0.0018 18.1 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit EXS PF03124.9 KLO16962.1 - 1.2e-82 277.7 4.3 1.5e-82 277.4 3.0 1.1 1 0 0 1 1 1 1 EXS family Anticodon_1 PF08264.8 KLO16962.1 - 0.077 12.7 0.0 0.13 11.9 0.0 1.3 1 0 0 1 1 1 0 Anticodon-binding domain of tRNA zf-C2H2_jaz PF12171.3 KLO16963.1 - 3.6e-06 26.9 0.0 6.5e-06 26.1 0.0 1.5 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 KLO16963.1 - 0.00024 21.1 0.1 0.00047 20.2 0.1 1.5 1 0 0 1 1 1 1 Zinc-finger of C2H2 type DUF1777 PF08648.7 KLO16963.1 - 0.0027 17.4 6.0 0.0027 17.4 4.1 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF1777) zf-DBF PF07535.7 KLO16963.1 - 0.013 15.1 0.0 0.025 14.2 0.0 1.4 1 0 0 1 1 1 0 DBF zinc finger DUF4660 PF15559.1 KLO16963.1 - 0.034 14.2 2.7 0.034 14.2 1.9 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4660) Pro_isomerase PF00160.16 KLO16964.1 - 2.1e-46 157.9 0.4 2.9e-46 157.4 0.3 1.2 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD DPBB_1 PF03330.13 KLO16965.1 - 3.6e-05 23.6 0.1 6.7e-05 22.8 0.1 1.5 1 0 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Bromodomain PF00439.20 KLO16967.1 - 1.2e-25 89.2 1.8 1.3e-25 89.1 0.3 1.8 2 0 0 2 2 2 1 Bromodomain Acetyltransf_7 PF13508.1 KLO16967.1 - 3.2e-08 33.6 0.4 6.6e-08 32.6 0.3 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 KLO16967.1 - 1.4e-06 28.1 0.2 3e-06 27.1 0.1 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 KLO16967.1 - 0.02 15.0 0.0 0.049 13.7 0.0 1.7 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain 2-Hacid_dh_C PF02826.14 KLO16968.1 - 4.3e-46 156.2 0.0 5.8e-46 155.8 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 KLO16968.1 - 8e-19 67.4 0.0 1.1e-18 66.9 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 KLO16968.1 - 1.4e-05 25.0 0.0 3.2e-05 23.8 0.0 1.6 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_7 PF13241.1 KLO16968.1 - 0.035 14.3 0.1 7 6.9 0.0 2.5 2 0 0 2 2 2 0 Putative NAD(P)-binding Pyocin_S PF06958.7 KLO16971.1 - 8.8 6.6 9.4 0.34 11.2 0.3 2.6 2 0 0 2 2 2 0 S-type Pyocin LAG1-DNAbind PF09271.6 KLO16974.1 - 6e-35 120.7 0.0 1e-34 120.0 0.0 1.4 1 0 0 1 1 1 1 LAG1, DNA binding BTD PF09270.5 KLO16974.1 - 8.9e-23 80.7 0.0 1.8e-20 73.2 0.0 3.0 1 1 0 1 1 1 1 Beta-trefoil DNA-binding domain ABC_tran PF00005.22 KLO16981.1 - 5e-23 81.9 0.0 6.9e-23 81.4 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 KLO16981.1 - 1.5e-10 41.4 0.0 0.00051 20.0 0.0 2.1 1 1 0 2 2 2 2 AAA domain SMC_N PF02463.14 KLO16981.1 - 4.9e-05 22.6 0.1 0.089 12.0 0.6 2.1 1 1 1 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 KLO16981.1 - 0.0051 16.3 0.0 0.0098 15.4 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_22 PF13401.1 KLO16981.1 - 0.013 15.6 0.0 0.031 14.4 0.0 1.8 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.1 KLO16981.1 - 0.016 15.1 0.0 0.028 14.3 0.0 1.7 1 1 0 1 1 1 0 AAA ATPase domain AAA_23 PF13476.1 KLO16981.1 - 0.027 14.8 0.1 0.059 13.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain SbcCD_C PF13558.1 KLO16981.1 - 0.029 14.2 0.1 0.066 13.1 0.0 1.6 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit DUF258 PF03193.11 KLO16981.1 - 0.05 12.7 0.0 0.098 11.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_30 PF13604.1 KLO16981.1 - 0.053 13.1 0.0 0.11 12.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain DUF815 PF05673.8 KLO16981.1 - 0.13 11.1 0.0 0.19 10.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AP_endonuc_2 PF01261.19 KLO16982.1 - 4e-25 88.3 0.0 5.4e-25 87.9 0.0 1.2 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel DUF2296 PF10058.4 KLO16983.1 - 7.1e-21 73.7 0.4 1.3e-20 72.9 0.3 1.4 1 0 0 1 1 1 1 Predicted integral membrane metal-binding protein (DUF2296) SMN PF06003.7 KLO16983.1 - 0.0026 16.9 0.1 0.0026 16.9 0.0 1.7 2 0 0 2 2 2 1 Survival motor neuron protein (SMN) WD40 PF00400.27 KLO16984.1 - 9.5e-71 231.3 14.3 9.8e-13 47.4 0.1 8.0 7 1 0 7 7 7 7 WD domain, G-beta repeat eIF2A PF08662.6 KLO16984.1 - 7.2e-08 32.3 1.6 0.00018 21.3 0.1 3.6 1 1 2 4 4 4 2 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 KLO16984.1 - 6e-05 21.3 9.5 0.93 7.5 0.0 5.0 2 2 3 5 5 5 3 Nucleoporin Nup120/160 DUF3312 PF11768.3 KLO16984.1 - 0.0062 14.8 0.0 0.019 13.2 0.0 1.7 1 1 1 2 2 2 1 Protein of unknown function (DUF3312) PQQ_2 PF13360.1 KLO16984.1 - 0.0077 15.7 2.8 2.6 7.4 0.2 3.1 1 1 2 3 3 3 1 PQQ-like domain PQQ_3 PF13570.1 KLO16984.1 - 0.023 14.9 0.1 4.6 7.6 0.0 3.5 3 0 0 3 3 3 0 PQQ-like domain Nbas_N PF15492.1 KLO16984.1 - 0.03 13.4 0.4 2 7.4 0.0 2.7 2 1 0 3 3 3 0 Neuroblastoma-amplified sequence, N terminal DUF1513 PF07433.6 KLO16984.1 - 0.056 12.3 0.0 0.25 10.2 0.0 1.9 1 1 1 3 3 3 0 Protein of unknown function (DUF1513) Hira PF07569.6 KLO16984.1 - 0.15 11.2 0.3 32 3.6 0.0 3.3 2 1 1 3 3 3 0 TUP1-like enhancer of split PCI_Csn8 PF10075.4 KLO16985.1 - 3.6e-23 81.9 0.0 5.3e-23 81.3 0.0 1.3 1 0 0 1 1 1 1 COP9 signalosome, subunit CSN8 SAC3_GANP PF03399.11 KLO16985.1 - 3.6e-19 69.1 0.2 5e-19 68.6 0.1 1.2 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family Aa_trans PF01490.13 KLO16986.1 - 2.5e-54 184.3 19.2 3e-54 184.0 13.3 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.8 KLO16986.1 - 0.00012 20.9 11.3 0.00032 19.6 7.8 1.8 1 1 0 1 1 1 1 Tryptophan/tyrosine permease family PrgI PF12666.2 KLO16986.1 - 0.31 11.2 0.1 0.31 11.2 0.1 4.3 4 2 0 4 4 4 0 PrgI family protein WAC_Acf1_DNA_bd PF10537.4 KLO16987.1 - 1e-34 118.7 0.8 2.8e-34 117.3 0.6 1.8 1 0 0 1 1 1 1 ATP-utilising chromatin assembly and remodelling N-terminal DDT PF02791.12 KLO16987.1 - 1.8e-12 46.8 0.0 4.6e-12 45.5 0.0 1.6 1 0 0 1 1 1 1 DDT domain WHIM1 PF15612.1 KLO16987.1 - 7.5e-05 22.4 0.1 0.00026 20.7 0.0 2.0 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 1 WHIM3 PF15614.1 KLO16987.1 - 0.0012 18.5 0.2 0.0044 16.7 0.1 2.0 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 3 WHIM2 PF15613.1 KLO16987.1 - 0.0035 17.2 0.2 0.012 15.5 0.1 1.9 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 2 Peptidase_M13 PF01431.16 KLO16987.1 - 0.26 10.4 2.6 0.49 9.5 1.8 1.4 1 0 0 1 1 1 0 Peptidase family M13 RdRP PF05183.7 KLO16989.1 - 1.1e-149 499.8 0.0 1.4e-149 499.4 0.0 1.1 1 0 0 1 1 1 1 RNA dependent RNA polymerase RdRP PF05183.7 KLO16990.1 - 1.4e-145 486.3 0.0 1.7e-145 485.9 0.0 1.1 1 0 0 1 1 1 1 RNA dependent RNA polymerase Sec7 PF01369.15 KLO16991.1 - 4e-39 134.2 0.0 6.1e-39 133.6 0.0 1.2 1 0 0 1 1 1 1 Sec7 domain PH_9 PF15410.1 KLO16991.1 - 1.4e-09 38.0 0.0 3.4e-09 36.8 0.0 1.7 1 0 0 1 1 1 1 Pleckstrin homology domain PH PF00169.24 KLO16991.1 - 3.5e-09 36.7 0.0 6.2e-09 36.0 0.0 1.4 1 0 0 1 1 1 1 PH domain Pescadillo_N PF06732.6 KLO16992.1 - 4.9e-117 390.1 0.1 4.9e-117 390.1 0.1 2.1 2 0 0 2 2 2 1 Pescadillo N-terminus BRCT PF00533.21 KLO16992.1 - 8.5e-09 35.4 0.0 2.3e-08 34.0 0.0 1.8 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain LSM PF01423.17 KLO16993.1 - 3.6e-17 61.6 0.8 5.5e-17 61.0 0.6 1.3 1 0 0 1 1 1 1 LSM domain GFO_IDH_MocA PF01408.17 KLO16994.1 - 1.3e-11 45.0 0.2 5e-11 43.1 0.2 2.0 1 1 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 KLO16994.1 - 0.0016 18.1 0.1 0.0098 15.6 0.0 2.2 1 1 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain Saccharop_dh PF03435.13 KLO16994.1 - 0.079 11.9 0.0 0.13 11.2 0.0 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase Cyclin_N PF00134.18 KLO16996.1 - 2.3e-36 124.1 0.6 2.3e-36 124.1 0.4 1.7 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 KLO16996.1 - 5.3e-10 39.2 0.1 1.2e-09 38.0 0.1 1.7 1 0 0 1 1 1 1 Cyclin, C-terminal domain Complex1_LYR PF05347.10 KLO16999.1 - 1.8e-15 56.4 0.1 2.1e-15 56.2 0.0 1.1 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 KLO16999.1 - 1.1e-14 54.4 0.0 1.2e-14 54.2 0.0 1.1 1 0 0 1 1 1 1 Complex1_LYR-like Rad21_Rec8_N PF04825.8 KLO17000.1 - 1.6e-23 82.7 0.0 3.4e-23 81.7 0.0 1.5 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein Rad21_Rec8 PF04824.11 KLO17000.1 - 7.2e-10 37.9 0.0 1.6e-09 36.7 0.0 1.6 1 0 0 1 1 1 1 Conserved region of Rad21 / Rec8 like protein ScpA_ScpB PF02616.9 KLO17000.1 - 0.087 12.3 2.7 0.27 10.8 0.0 2.7 3 0 0 3 3 3 0 ScpA/B protein NUDIX PF00293.23 KLO17001.1 - 2e-27 95.4 0.0 2.9e-27 94.9 0.0 1.2 1 0 0 1 1 1 1 NUDIX domain DUF4281 PF14108.1 KLO17001.1 - 0.034 14.2 0.1 0.052 13.6 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4281) Ribosomal_S17 PF00366.15 KLO17002.1 - 2.3e-31 107.6 1.5 2.3e-31 107.6 1.0 1.7 2 0 0 2 2 2 1 Ribosomal protein S17 Metallophos PF00149.23 KLO17003.1 - 1.1e-36 126.1 0.1 1.4e-36 125.7 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase WD40 PF00400.27 KLO17004.1 - 2.6e-17 61.9 3.8 1.2e-07 31.2 0.0 4.3 4 0 0 4 4 4 3 WD domain, G-beta repeat MPC PF03650.8 KLO17006.1 - 2.3e-37 127.5 0.2 2.9e-37 127.2 0.1 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0041) DNA_ligase_A_M PF01068.16 KLO17007.1 - 3.7e-60 202.7 0.2 6.3e-60 202.0 0.2 1.4 1 0 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.9 KLO17007.1 - 6.3e-53 179.2 0.7 2e-52 177.6 0.4 1.8 2 0 0 2 2 2 1 DNA ligase N terminus DNA_ligase_A_C PF04679.10 KLO17007.1 - 1.4e-25 89.4 0.0 4e-25 88.0 0.0 1.8 1 0 0 1 1 1 1 ATP dependent DNA ligase C terminal region DNA_ligase_OB_2 PF14743.1 KLO17007.1 - 0.0048 16.5 0.1 1.8 8.3 0.0 2.6 2 0 0 2 2 2 2 DNA ligase OB-like domain SET PF00856.23 KLO17008.1 - 9e-24 84.6 1.9 9e-24 84.6 1.3 2.8 2 2 0 2 2 2 1 SET domain Pre-SET PF05033.11 KLO17008.1 - 5.4e-12 45.8 10.2 4e-11 43.1 4.6 2.5 2 0 0 2 2 2 1 Pre-SET motif Chromo PF00385.19 KLO17008.1 - 0.00032 20.2 5.2 0.00069 19.2 3.6 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain EmrE PF13536.1 KLO17009.1 - 6.1e-10 39.3 30.0 1.1e-09 38.4 3.4 2.9 3 1 0 3 3 3 2 Multidrug resistance efflux transporter EamA PF00892.15 KLO17009.1 - 0.00016 21.6 1.8 0.00016 21.6 1.3 3.2 4 1 0 4 4 4 2 EamA-like transporter family Ribosomal_L36 PF00444.13 KLO17010.1 - 1.2e-17 63.5 9.4 2e-17 62.8 6.5 1.3 1 0 0 1 1 1 1 Ribosomal protein L36 DHFR_1 PF00186.14 KLO17011.1 - 7.4e-30 103.6 0.0 4.5e-26 91.3 0.0 2.5 2 1 0 2 2 2 2 Dihydrofolate reductase RTA1 PF04479.8 KLO17012.1 - 1.3e-43 149.1 0.0 1.8e-43 148.6 0.0 1.1 1 0 0 1 1 1 1 RTA1 like protein RTA1 PF04479.8 KLO17013.1 - 2.6e-42 144.8 0.6 3.3e-42 144.4 0.4 1.1 1 0 0 1 1 1 1 RTA1 like protein Bac_export_1 PF01311.15 KLO17013.1 - 0.0044 16.3 0.7 0.01 15.1 0.5 1.5 1 0 0 1 1 1 1 Bacterial export proteins, family 1 RTA1 PF04479.8 KLO17014.1 - 1.2e-46 159.0 5.5 1.2e-46 159.0 3.8 1.5 2 0 0 2 2 2 1 RTA1 like protein Isochorismatase PF00857.15 KLO17015.1 - 1.8e-26 93.1 0.0 2.7e-26 92.5 0.0 1.3 1 0 0 1 1 1 1 Isochorismatase family OppC_N PF12911.2 KLO17016.1 - 0.049 13.0 1.1 0.11 11.8 0.7 1.6 1 0 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C Galactosyl_T PF01762.16 KLO17017.1 - 4.1e-08 33.0 0.1 0.00029 20.5 0.0 2.6 2 1 0 2 2 2 2 Galactosyltransferase GST_N_3 PF13417.1 KLO17018.1 - 7.5e-06 26.0 0.0 1.9e-05 24.7 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 KLO17018.1 - 3e-05 23.8 0.0 7.8e-05 22.4 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 KLO17018.1 - 7.9e-05 22.5 0.0 0.00016 21.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 KLO17018.1 - 0.00025 20.9 0.0 0.032 14.2 0.0 2.9 3 0 0 3 3 3 1 Glutathione S-transferase, C-terminal domain p450 PF00067.17 KLO17020.1 - 3.7e-64 216.9 0.0 4.7e-64 216.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 SGS PF05002.10 KLO17022.1 - 1.5e-31 107.9 2.0 3.5e-31 106.7 1.4 1.6 1 0 0 1 1 1 1 SGS domain CS PF04969.11 KLO17022.1 - 4.3e-07 30.4 0.0 7e-07 29.7 0.0 1.4 1 0 0 1 1 1 1 CS domain OppC_N PF12911.2 KLO17023.1 - 0.094 12.0 0.8 0.24 10.7 0.5 1.7 1 0 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C PMP1_2 PF08114.6 KLO17023.1 - 0.47 9.9 1.7 0.9 9.0 1.2 1.3 1 0 0 1 1 1 0 ATPase proteolipid family Ras PF00071.17 KLO17024.1 - 6.1e-55 185.0 0.0 7.4e-55 184.7 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KLO17024.1 - 1.6e-18 67.3 0.0 2.2e-18 66.8 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KLO17024.1 - 1.7e-12 46.9 0.0 2.3e-12 46.5 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 KLO17024.1 - 4.7e-06 26.1 0.0 5.3e-05 22.7 0.0 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 KLO17024.1 - 4.5e-05 23.3 0.0 6.2e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 KLO17024.1 - 0.0002 20.5 0.0 0.00025 20.2 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_22 PF13401.1 KLO17024.1 - 0.0017 18.5 0.0 0.004 17.3 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 KLO17024.1 - 0.0063 16.5 0.1 0.012 15.5 0.1 1.6 1 1 0 1 1 1 1 AAA ATPase domain SRPRB PF09439.5 KLO17024.1 - 0.0069 15.6 0.0 0.01 15.0 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit ATP_bind_1 PF03029.12 KLO17024.1 - 0.0098 15.4 0.0 0.66 9.4 0.0 2.1 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein NACHT PF05729.7 KLO17024.1 - 0.034 13.8 0.0 0.065 12.8 0.0 1.4 1 0 0 1 1 1 0 NACHT domain DUF2075 PF09848.4 KLO17024.1 - 0.07 12.0 0.0 0.1 11.5 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Septin PF00735.13 KLO17024.1 - 0.087 11.8 0.0 0.12 11.3 0.0 1.2 1 0 0 1 1 1 0 Septin Methyltransf_25 PF13649.1 KLO17024.1 - 0.11 12.9 0.0 0.19 12.0 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain DAP3 PF10236.4 KLO17024.1 - 0.13 11.1 0.0 0.2 10.5 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 KaiC PF06745.8 KLO17024.1 - 0.15 11.1 0.0 0.27 10.3 0.0 1.4 1 0 0 1 1 1 0 KaiC D-ser_dehydrat PF14031.1 KLO17025.1 - 1.7e-19 69.8 0.1 5.2e-18 65.0 0.0 2.8 2 1 0 3 3 3 1 Putative serine dehydratase domain Ala_racemase_N PF01168.15 KLO17025.1 - 2.6e-12 46.7 0.0 3.6e-12 46.3 0.0 1.2 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain Abhydrolase_3 PF07859.8 KLO17026.1 - 1.9e-60 204.0 0.0 2.7e-60 203.5 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.23 KLO17026.1 - 1.2e-09 37.4 0.2 2.2e-09 36.6 0.1 1.4 1 1 0 1 1 1 1 Carboxylesterase family Peptidase_S9 PF00326.16 KLO17026.1 - 0.05 12.8 0.2 1 8.5 0.1 2.6 1 1 0 1 1 1 0 Prolyl oligopeptidase family DUF2424 PF10340.4 KLO17026.1 - 0.18 10.4 0.0 0.23 10.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2424) 4HBT_3 PF13622.1 KLO17027.1 - 1.7e-35 122.9 0.0 2.1e-35 122.7 0.0 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily Acyl_CoA_thio PF02551.10 KLO17027.1 - 9.8e-23 80.2 0.0 9.3e-18 64.1 0.0 3.1 2 1 0 2 2 2 2 Acyl-CoA thioesterase DS PF01916.12 KLO17027.1 - 0.009 15.1 0.0 0.015 14.4 0.0 1.3 1 0 0 1 1 1 1 Deoxyhypusine synthase RRM_1 PF00076.17 KLO17028.1 - 2.5e-42 142.3 0.1 1.2e-19 69.7 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KLO17028.1 - 2.2e-32 110.8 0.1 1.1e-13 50.8 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KLO17028.1 - 1.3e-25 89.0 0.1 6.1e-11 42.0 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RBM39linker PF15519.1 KLO17028.1 - 4.6e-17 62.0 0.4 9.2e-17 61.1 0.3 1.5 1 0 0 1 1 1 1 linker between RRM2 and RRM3 domains in RBM39 protein RRM_3 PF08777.6 KLO17028.1 - 6.1e-08 32.4 0.3 0.00078 19.2 0.0 2.5 2 0 0 2 2 2 2 RNA binding motif Limkain-b1 PF11608.3 KLO17028.1 - 0.0087 15.7 0.1 18 5.1 0.0 3.3 3 0 0 3 3 3 1 Limkain b1 IlvN PF07991.7 KLO17029.1 - 3.7e-49 166.2 0.0 5.3e-49 165.7 0.0 1.2 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain F420_oxidored PF03807.12 KLO17029.1 - 4.3e-10 39.8 0.0 9.2e-10 38.8 0.0 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent IlvC PF01450.14 KLO17029.1 - 1.7e-06 28.0 0.0 2.7e-06 27.3 0.0 1.3 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain NAD_binding_2 PF03446.10 KLO17029.1 - 1.8e-06 27.9 0.0 2.9e-06 27.2 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase 2-Hacid_dh_C PF02826.14 KLO17029.1 - 0.00055 19.1 0.0 0.00092 18.3 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_Gly3P_dh_N PF01210.18 KLO17029.1 - 0.0048 16.6 0.1 0.061 13.0 0.0 2.2 1 1 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Shikimate_DH PF01488.15 KLO17029.1 - 0.034 14.2 0.0 0.055 13.5 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase adh_short PF00106.20 KLO17030.1 - 1.2e-26 93.5 0.1 1.8e-26 93.0 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KLO17030.1 - 2.7e-24 86.2 0.0 3.4e-24 85.9 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KLO17030.1 - 1.1e-10 41.5 0.1 1.6e-10 40.9 0.1 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 KLO17030.1 - 0.057 12.8 0.0 0.076 12.4 0.0 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.3 KLO17030.1 - 0.063 13.0 1.7 0.21 11.4 0.7 2.1 1 1 1 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Cupin_2 PF07883.6 KLO17031.1 - 1.9e-06 27.2 0.0 3.5e-06 26.4 0.0 1.4 1 0 0 1 1 1 1 Cupin domain GATase_4 PF13230.1 KLO17032.1 - 2.8e-23 81.9 0.0 4.2e-23 81.3 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferases class-II GATase_6 PF13522.1 KLO17032.1 - 1.6e-10 41.0 0.0 2.7e-10 40.3 0.0 1.5 1 1 0 1 1 1 1 Glutamine amidotransferase domain GATase_2 PF00310.16 KLO17032.1 - 1.8e-07 30.2 0.0 4.7e-07 28.8 0.0 1.6 2 0 0 2 2 2 1 Glutamine amidotransferases class-II PGM_PMM_I PF02878.11 KLO17033.1 - 1.2e-14 53.9 0.5 1.8e-07 30.7 0.0 2.8 2 1 1 3 3 3 2 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_II PF02879.11 KLO17033.1 - 3.4e-14 53.0 0.0 1.2e-13 51.3 0.0 2.0 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.15 KLO17033.1 - 5e-12 45.6 0.3 1.1e-11 44.5 0.2 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain ATP-grasp_2 PF08442.5 KLO17033.1 - 0.068 12.5 0.0 0.26 10.6 0.0 1.8 2 0 0 2 2 2 0 ATP-grasp domain SNAP PF14938.1 KLO17034.1 - 2.5e-92 309.0 15.3 2.8e-92 308.8 10.6 1.0 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP TPR_12 PF13424.1 KLO17034.1 - 1.4e-09 37.7 10.4 1.2e-05 25.1 1.1 2.4 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.1 KLO17034.1 - 0.00025 20.6 6.8 0.006 16.2 0.1 5.0 5 1 0 5 5 5 1 Tetratricopeptide repeat TPR_11 PF13414.1 KLO17034.1 - 0.025 14.2 14.3 0.57 9.8 4.6 3.3 3 0 0 3 3 3 0 TPR repeat TPR_8 PF13181.1 KLO17034.1 - 0.039 13.7 11.1 2 8.3 0.0 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat TRAPPC-Trs85 PF12739.2 KLO17034.1 - 0.11 11.1 2.4 0.99 7.9 1.1 2.2 1 1 1 2 2 2 0 ER-Golgi trafficking TRAPP I complex 85 kDa subunit TPR_9 PF13371.1 KLO17034.1 - 0.17 11.7 2.5 0.87 9.4 0.5 2.5 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_1 PF00515.23 KLO17034.1 - 0.33 10.6 13.1 0.45 10.2 0.1 4.6 4 1 1 5 5 5 0 Tetratricopeptide repeat TPR_14 PF13428.1 KLO17034.1 - 0.49 11.1 9.4 0.66 10.7 0.2 4.5 4 1 1 5 5 4 0 Tetratricopeptide repeat TPR_6 PF13174.1 KLO17034.1 - 0.92 10.1 11.7 2.5 8.7 0.2 5.4 4 1 1 5 5 5 0 Tetratricopeptide repeat TPR_2 PF07719.12 KLO17034.1 - 0.93 9.5 16.9 0.59 10.1 0.2 4.9 4 1 0 4 4 4 0 Tetratricopeptide repeat DUF947 PF06102.7 KLO17037.1 - 3.2e-35 121.4 20.8 3.2e-35 121.4 14.4 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF947) CorA PF01544.13 KLO17038.1 - 2e-23 82.8 2.7 2.2e-12 46.6 0.2 3.2 2 1 0 2 2 2 2 CorA-like Mg2+ transporter protein zf-DHHC PF01529.15 KLO17038.1 - 0.14 11.5 0.2 0.27 10.6 0.1 1.4 1 0 0 1 1 1 0 DHHC palmitoyltransferase Pex16 PF08610.5 KLO17040.1 - 2.7e-71 240.3 0.6 3.1e-71 240.1 0.4 1.0 1 0 0 1 1 1 1 Peroxisomal membrane protein (Pex16) ICE2 PF08426.5 KLO17041.1 - 8.2e-21 74.0 29.9 1.5e-13 50.1 11.8 3.0 1 1 2 3 3 3 3 ICE2 LMWPc PF01451.16 KLO17042.1 - 1.1e-38 132.7 0.0 1.2e-38 132.5 0.0 1.0 1 0 0 1 1 1 1 Low molecular weight phosphotyrosine protein phosphatase SH3BGR PF04908.10 KLO17043.1 - 1e-07 31.8 0.0 1.7e-07 31.0 0.0 1.4 1 0 0 1 1 1 1 SH3-binding, glutamic acid-rich protein Glutaredoxin PF00462.19 KLO17043.1 - 0.1 12.6 0.0 0.19 11.7 0.0 1.4 1 0 0 1 1 1 0 Glutaredoxin adh_short PF00106.20 KLO17044.1 - 3.1e-26 92.2 0.0 4.6e-26 91.7 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KLO17044.1 - 1.6e-23 83.7 0.1 2.7e-23 82.9 0.0 1.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KLO17044.1 - 2.3e-08 33.9 0.0 5e-08 32.8 0.0 1.5 2 0 0 2 2 2 1 KR domain Epimerase PF01370.16 KLO17044.1 - 0.0079 15.6 0.0 0.042 13.2 0.0 2.1 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family THF_DHG_CYH_C PF02882.14 KLO17044.1 - 0.014 14.4 0.0 0.024 13.7 0.0 1.3 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain DUF1776 PF08643.5 KLO17044.1 - 0.058 12.5 0.0 0.37 9.8 0.0 1.9 2 0 0 2 2 2 0 Fungal family of unknown function (DUF1776) Eno-Rase_NADH_b PF12242.3 KLO17044.1 - 0.09 12.5 0.3 0.24 11.2 0.2 1.7 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase PhyH PF05721.8 KLO17045.1 - 0.00017 21.7 0.0 0.00059 19.9 0.0 1.9 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) 2-Hacid_dh_C PF02826.14 KLO17046.1 - 2.8e-49 166.6 0.0 5.5e-49 165.7 0.0 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 KLO17046.1 - 2.5e-30 104.6 0.0 3.9e-30 104.0 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 KLO17046.1 - 0.0025 17.6 0.0 0.0052 16.6 0.0 1.5 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase 3HCDH_N PF02737.13 KLO17046.1 - 0.12 12.0 0.0 0.67 9.5 0.0 2.2 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain His_biosynth PF00977.16 KLO17047.1 - 2.7e-43 147.8 0.0 4.4e-42 143.8 0.0 2.5 1 1 0 1 1 1 1 Histidine biosynthesis protein GATase PF00117.23 KLO17047.1 - 1.2e-24 86.8 0.0 2e-24 86.1 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I GATase_3 PF07685.9 KLO17047.1 - 4.6e-09 36.0 0.0 1e-08 34.9 0.0 1.6 1 1 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain SNO PF01174.14 KLO17047.1 - 8.6e-07 28.7 0.0 0.00018 21.1 0.0 2.4 2 0 0 2 2 2 2 SNO glutamine amidotransferase family Peptidase_C26 PF07722.8 KLO17047.1 - 0.026 13.9 0.5 0.44 9.9 0.2 2.6 2 1 0 2 2 2 0 Peptidase C26 Pal1 PF08316.6 KLO17048.1 - 2.6e-16 60.3 0.7 2.6e-16 60.3 0.5 2.1 3 0 0 3 3 3 1 Pal1 cell morphology protein FA_desaturase PF00487.19 KLO17049.1 - 2.8e-30 105.6 25.1 4.7e-30 104.8 17.4 1.4 1 0 0 1 1 1 1 Fatty acid desaturase Cyt-b5 PF00173.23 KLO17049.1 - 3.1e-11 42.9 0.0 6.4e-11 41.8 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Meth_synt_2 PF01717.13 KLO17052.1 - 2.5e-16 59.5 0.0 4.5e-12 45.5 0.0 2.1 2 0 0 2 2 2 2 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.7 KLO17052.1 - 9.9e-08 31.6 0.0 0.011 15.0 0.0 3.5 3 1 1 4 4 4 2 Cobalamin-independent synthase, N-terminal domain Meth_synt_2 PF01717.13 KLO17053.1 - 7e-18 64.6 0.0 7.7e-12 44.8 0.0 2.1 2 0 0 2 2 2 2 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.7 KLO17053.1 - 2.4e-09 36.9 0.0 0.003 16.8 0.0 3.3 3 1 0 3 3 3 2 Cobalamin-independent synthase, N-terminal domain Ribosomal_L13e PF01294.13 KLO17054.1 - 8.7e-69 230.5 2.9 1.3e-68 229.9 2.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L13e Ribosomal_L4 PF00573.17 KLO17055.1 - 2.3e-55 186.9 0.0 3.1e-55 186.5 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family Ribosomal_S9 PF00380.14 KLO17056.1 - 4.5e-38 130.2 1.6 5.1e-38 130.0 1.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S9/S16 Rap1-DNA-bind PF09197.5 KLO17058.1 - 0.0021 18.5 2.5 21 5.7 0.0 3.6 3 0 0 3 3 3 3 Rap1, DNA-binding CHDNT PF08073.7 KLO17058.1 - 0.038 13.6 0.1 1.9 8.2 0.0 2.5 2 0 0 2 2 2 0 CHDNT (NUC034) domain Mito_carr PF00153.22 KLO17059.1 - 2.1e-64 213.2 6.7 2.8e-23 81.4 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF3089 PF11288.3 KLO17059.1 - 0.046 12.8 0.1 3.9 6.5 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3089) PINIT PF14324.1 KLO17060.1 - 2.8e-35 121.5 1.8 6.2e-35 120.3 1.2 1.6 1 0 0 1 1 1 1 PINIT domain zf-MIZ PF02891.15 KLO17060.1 - 1.3e-16 59.8 8.2 2.3e-16 59.0 5.7 1.4 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger zf-Nse PF11789.3 KLO17060.1 - 9.1e-07 28.3 2.1 1.8e-06 27.3 1.5 1.5 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit SAP PF02037.22 KLO17060.1 - 0.00046 19.6 0.6 0.0034 16.8 0.0 2.4 2 0 0 2 2 2 1 SAP domain PfUIS3 PF11567.3 KLO17060.1 - 0.2 11.7 0.0 0.37 10.9 0.0 1.3 1 0 0 1 1 1 0 Plasmodium falciparum UIS3 membrane protein CS PF04969.11 KLO17061.1 - 3.5e-19 69.1 1.2 3.7e-19 69.0 0.2 1.5 2 0 0 2 2 2 1 CS domain PhosphMutase PF10143.4 KLO17061.1 - 0.0053 16.4 0.2 0.0083 15.7 0.1 1.3 1 0 0 1 1 1 1 2,3-bisphosphoglycerate-independent phosphoglycerate mutase ResIII PF04851.10 KLO17062.1 - 5.4e-21 75.2 0.0 9.5e-21 74.4 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.24 KLO17062.1 - 2.1e-16 59.8 0.0 3.8e-16 59.0 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KLO17062.1 - 1.8e-13 50.1 0.0 4.4e-13 48.9 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SNF2_N PF00176.18 KLO17062.1 - 4e-08 32.4 0.0 6.4e-08 31.7 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain DUF2075 PF09848.4 KLO17062.1 - 0.00024 20.2 0.0 0.00042 19.3 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_22 PF13401.1 KLO17062.1 - 0.00055 20.0 0.0 0.0014 18.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain cobW PF02492.14 KLO17062.1 - 0.0031 16.9 0.0 0.0056 16.1 0.0 1.3 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain DEAD_2 PF06733.10 KLO17062.1 - 0.0034 16.7 0.0 0.0064 15.9 0.0 1.4 1 0 0 1 1 1 1 DEAD_2 AAA_11 PF13086.1 KLO17062.1 - 0.0041 16.7 0.1 1.7 8.1 0.0 2.6 2 1 1 3 3 3 2 AAA domain Helicase_C_2 PF13307.1 KLO17062.1 - 0.012 15.5 0.0 0.053 13.4 0.0 2.1 2 0 0 2 2 2 0 Helicase C-terminal domain T2SE PF00437.15 KLO17062.1 - 0.049 12.5 0.0 0.082 11.7 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein ABC_tran PF00005.22 KLO17062.1 - 0.07 13.4 0.1 2.9 8.1 0.0 2.4 2 0 0 2 2 2 0 ABC transporter Indigoidine_A PF04227.7 KLO17063.1 - 1.8e-112 375.3 0.0 2.9e-112 374.6 0.0 1.3 1 0 0 1 1 1 1 Indigoidine synthase A like protein PfkB PF00294.19 KLO17063.1 - 2.7e-13 49.7 0.5 7.5e-06 25.2 0.1 2.8 2 1 0 2 2 2 2 pfkB family carbohydrate kinase MoaE PF02391.12 KLO17064.1 - 1.1e-30 105.8 0.1 1.5e-30 105.4 0.0 1.2 1 0 0 1 1 1 1 MoaE protein Baculo_E25 PF05274.6 KLO17064.1 - 0.081 12.5 0.0 0.11 12.0 0.0 1.2 1 0 0 1 1 1 0 Occlusion-derived virus envelope protein E25 LEAP-2 PF07359.6 KLO17065.1 - 0.0014 18.2 0.1 17 5.1 0.0 4.1 3 1 1 4 4 4 2 Liver-expressed antimicrobial peptide 2 precursor (LEAP-2) ROKNT PF08067.6 KLO17065.1 - 0.017 14.9 2.8 1.1e+02 2.7 0.0 5.5 4 2 0 4 4 4 0 ROKNT (NUC014) domain DUF3621 PF12285.3 KLO17065.1 - 0.046 13.8 14.8 8.8 6.5 0.2 6.4 1 1 7 8 8 8 0 Protein of unknown function (DUF3621) Tropomodulin PF03250.9 KLO17065.1 - 0.081 12.4 0.5 5 6.6 0.0 2.7 1 1 2 3 3 3 0 Tropomodulin KAAG1 PF15354.1 KLO17065.1 - 0.81 10.0 13.4 11 6.4 0.2 4.5 3 1 2 5 5 5 0 Kidney-associated antigen 1 NUC153 PF08159.7 KLO17066.1 - 1.3e-13 50.2 0.2 1.3e-13 50.2 0.1 3.8 3 0 0 3 3 3 2 NUC153 domain Tim17 PF02466.14 KLO17067.1 - 1.3e-13 51.1 10.5 1.9e-13 50.6 7.3 1.2 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Bacteriocin_IIc PF10439.4 KLO17067.1 - 0.024 14.7 4.6 0.024 14.7 3.2 2.6 2 1 0 2 2 2 0 Bacteriocin class II with double-glycine leader peptide Aldedh PF00171.17 KLO17068.1 - 2.5e-129 431.6 0.1 3.3e-129 431.2 0.1 1.1 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 KLO17068.1 - 0.026 13.2 0.0 0.042 12.5 0.0 1.3 1 0 0 1 1 1 0 Acyl-CoA reductase (LuxC) RE_MjaI PF09568.5 KLO17069.1 - 0.016 14.7 2.9 0.62 9.5 0.3 3.0 3 0 0 3 3 3 0 MjaI restriction endonuclease TRAPPC-Trs85 PF12739.2 KLO17070.1 - 1.1e-30 106.6 0.0 1e-27 96.9 0.0 2.2 2 0 0 2 2 2 2 ER-Golgi trafficking TRAPP I complex 85 kDa subunit Dehydrin PF00257.14 KLO17071.1 - 0.071 13.4 0.6 0.095 13.0 0.4 1.2 1 0 0 1 1 1 0 Dehydrin zf-Sec23_Sec24 PF04810.10 KLO17072.1 - 0.017 14.6 0.5 0.031 13.8 0.4 1.3 1 0 0 1 1 1 0 Sec23/Sec24 zinc finger LCCL PF03815.14 KLO17073.1 - 1.8e-14 53.4 0.0 3.2e-14 52.6 0.0 1.4 1 0 0 1 1 1 1 LCCL domain TraL PF07178.6 KLO17073.1 - 0.31 11.0 4.4 0.13 12.3 0.2 2.5 2 0 0 2 2 2 0 TraL protein Seipin PF06775.9 KLO17075.1 - 3.9e-16 59.1 0.0 5e-15 55.5 0.0 2.1 1 1 0 1 1 1 1 Putative adipose-regulatory protein (Seipin) His_Phos_1 PF00300.17 KLO17076.1 - 5.1e-27 94.8 0.0 6.3e-27 94.6 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Pep3_Vps18 PF05131.9 KLO17077.1 - 6.9e-43 145.5 0.0 2e-42 144.0 0.0 1.9 1 0 0 1 1 1 1 Pep3/Vps18/deep orange family Clathrin PF00637.15 KLO17077.1 - 4.9e-08 32.6 7.9 1.1e-05 25.0 0.0 3.9 3 1 0 3 3 3 2 Region in Clathrin and VPS Vps39_2 PF10367.4 KLO17077.1 - 0.00026 21.1 0.0 0.00057 20.0 0.0 1.6 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 2 zf-RING_2 PF13639.1 KLO17077.1 - 0.00071 19.3 3.8 0.00098 18.9 1.2 2.1 2 0 0 2 2 2 1 Ring finger domain zf-RING_5 PF14634.1 KLO17077.1 - 0.0064 16.1 1.5 0.0064 16.1 1.0 1.8 2 0 0 2 2 2 1 zinc-RING finger domain DUF1664 PF07889.7 KLO17077.1 - 0.067 12.9 0.6 0.64 9.8 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) zf-C3HC4_3 PF13920.1 KLO17077.1 - 0.1 12.2 0.6 0.98 9.1 0.3 2.2 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 KLO17077.1 - 0.18 11.9 0.1 0.47 10.6 0.0 1.7 1 0 0 1 1 1 0 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 KLO17077.1 - 0.28 11.2 4.4 0.1 12.6 0.8 1.9 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KLO17077.1 - 8.7 6.0 5.6 0.88 9.2 0.6 1.8 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Cgr1 PF03879.9 KLO17078.1 - 1e-21 77.1 26.1 1.2e-21 76.9 18.1 1.0 1 0 0 1 1 1 1 Cgr1 family CAF-1_p150 PF11600.3 KLO17078.1 - 0.032 13.5 23.7 0.046 13.0 16.4 1.1 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal DUF155 PF02582.9 KLO17078.1 - 0.052 13.4 0.4 0.058 13.2 0.3 1.2 1 0 0 1 1 1 0 Uncharacterised ACR, YagE family COG1723 SPATIAL PF15256.1 KLO17078.1 - 0.21 11.6 8.7 0.25 11.3 6.0 1.1 1 0 0 1 1 1 0 SPATIAL APG6 PF04111.7 KLO17078.1 - 0.98 8.3 10.5 1.1 8.2 7.3 1.0 1 0 0 1 1 1 0 Autophagy protein Apg6 PBP_sp32 PF07222.7 KLO17078.1 - 1.5 7.8 8.2 1.9 7.6 5.7 1.1 1 0 0 1 1 1 0 Proacrosin binding protein sp32 Sec39 PF08314.6 KLO17080.1 - 2.9e-60 204.0 0.0 6.7e-60 202.8 0.0 1.6 1 1 0 1 1 1 1 Secretory pathway protein Sec39 UreD PF01774.12 KLO17081.1 - 6.1e-56 189.1 0.0 7.1e-56 188.9 0.0 1.0 1 0 0 1 1 1 1 UreD urease accessory protein MscS_porin PF12795.2 KLO17082.1 - 6.7e-05 22.3 21.0 6.7e-05 22.3 14.6 5.7 3 2 2 5 5 5 1 Mechanosensitive ion channel porin domain Filament PF00038.16 KLO17082.1 - 0.00039 19.9 106.7 0.0014 18.1 29.6 4.5 1 1 2 3 3 3 2 Intermediate filament protein IncA PF04156.9 KLO17082.1 - 0.0014 18.2 16.8 0.0014 18.2 11.6 7.7 2 1 7 9 9 8 5 IncA protein Nuc_N PF14448.1 KLO17082.1 - 0.0025 17.3 1.0 0.015 14.7 0.3 2.7 2 0 0 2 2 2 1 Nuclease N terminal Reo_sigmaC PF04582.7 KLO17082.1 - 0.0033 16.6 77.3 0.0078 15.4 7.6 6.9 2 1 5 7 7 7 4 Reovirus sigma C capsid protein zf-C4H2 PF10146.4 KLO17082.1 - 0.0054 16.7 6.5 0.0054 16.7 4.5 4.8 1 1 4 5 5 4 2 Zinc finger-containing protein AAA_13 PF13166.1 KLO17082.1 - 0.0075 14.7 93.0 0.0057 15.1 18.0 4.6 1 1 2 4 4 4 4 AAA domain DUF1816 PF08846.5 KLO17082.1 - 0.049 13.3 0.2 0.2 11.3 0.1 2.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1816) CENP-F_leu_zip PF10473.4 KLO17082.1 - 0.12 12.2 120.6 0.13 12.1 8.3 8.5 1 1 8 9 9 9 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF3584 PF12128.3 KLO17082.1 - 0.81 6.9 121.5 0.0022 15.4 22.6 4.6 1 1 2 4 4 4 0 Protein of unknown function (DUF3584) WD40_alt PF14077.1 KLO17082.1 - 3.4 7.3 19.6 1.6 8.4 0.2 6.0 7 0 0 7 7 7 0 Alternative WD40 repeat motif Mito_carr PF00153.22 KLO17083.1 - 1e-31 108.4 8.0 2.6e-14 52.6 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein PBP1_TM PF14812.1 KLO17084.1 - 0.43 10.9 4.7 2 8.7 3.3 2.1 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal zf-C2H2 PF00096.21 KLO17086.1 - 1.8e-12 46.8 15.0 5.7e-05 23.2 0.1 3.5 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KLO17086.1 - 9.9e-11 41.1 12.8 0.001 19.2 0.3 3.5 3 0 0 3 3 3 3 C2H2-type zinc finger zf-H2C2_2 PF13465.1 KLO17086.1 - 5.6e-09 35.8 14.5 6.7e-05 22.9 0.2 4.2 4 0 0 4 4 4 2 Zinc-finger double domain zf-met PF12874.2 KLO17086.1 - 0.00083 19.4 8.1 0.039 14.1 0.0 3.5 3 0 0 3 3 3 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 KLO17086.1 - 0.0039 17.2 8.8 0.083 13.0 0.0 3.5 3 0 0 3 3 3 1 Zinc-finger double-stranded RNA-binding zf-C2HC_2 PF13913.1 KLO17086.1 - 0.019 14.6 2.3 0.032 13.9 0.1 2.6 2 0 0 2 2 2 0 zinc-finger of a C2HC-type zf-TRAF PF02176.13 KLO17086.1 - 0.031 14.6 7.9 0.06 13.7 1.5 2.9 1 1 2 3 3 3 0 TRAF-type zinc finger IBR PF01485.16 KLO17086.1 - 0.073 12.9 5.0 0.95 9.3 1.5 2.3 1 1 1 2 2 2 0 IBR domain zf-C2H2_6 PF13912.1 KLO17086.1 - 0.12 12.2 3.2 7.4 6.6 0.0 3.1 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2_2 PF12756.2 KLO17086.1 - 0.22 11.6 2.7 1.1 9.3 0.1 2.3 1 1 0 2 2 2 0 C2H2 type zinc-finger (2 copies) Adeno_PIX PF03955.9 KLO17086.1 - 2 8.9 4.3 1.8 9.1 1.4 2.0 1 1 1 2 2 2 0 Adenovirus hexon-associated protein (IX) Zn-ribbon_8 PF09723.5 KLO17086.1 - 7.9 6.5 6.1 11 6.0 0.1 3.1 3 0 0 3 3 3 0 Zinc ribbon domain TPR_12 PF13424.1 KLO17087.1 - 1.2e-29 102.0 24.4 2.8e-09 36.7 0.5 6.2 4 1 4 8 8 7 6 Tetratricopeptide repeat SNAP PF14938.1 KLO17087.1 - 8.5e-11 41.5 12.7 0.00037 19.7 0.4 3.4 2 1 1 3 3 3 3 Soluble NSF attachment protein, SNAP AAA_16 PF13191.1 KLO17087.1 - 1.3e-08 35.0 0.5 4.2e-07 30.1 0.4 2.9 1 1 0 1 1 1 1 AAA ATPase domain TPR_2 PF07719.12 KLO17087.1 - 9.2e-08 31.4 13.5 0.041 13.7 0.4 8.1 8 0 0 8 8 7 2 Tetratricopeptide repeat TPR_10 PF13374.1 KLO17087.1 - 6.5e-07 29.0 10.7 0.14 12.1 0.1 6.7 6 0 0 6 6 6 2 Tetratricopeptide repeat NB-ARC PF00931.17 KLO17087.1 - 4.8e-06 25.6 0.0 4.9e-05 22.3 0.0 2.3 1 1 0 1 1 1 1 NB-ARC domain AAA_22 PF13401.1 KLO17087.1 - 3.3e-05 24.0 0.0 0.00013 22.0 0.0 2.1 1 0 0 1 1 1 1 AAA domain TPR_1 PF00515.23 KLO17087.1 - 0.00019 20.9 6.6 0.32 10.6 0.4 5.4 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_11 PF13414.1 KLO17087.1 - 0.00025 20.6 13.1 0.47 10.1 0.4 5.5 4 2 2 6 6 6 2 TPR repeat Arch_ATPase PF01637.13 KLO17087.1 - 0.0028 17.3 0.0 0.0086 15.7 0.0 1.8 2 0 0 2 2 1 1 Archaeal ATPase NACHT PF05729.7 KLO17087.1 - 0.0038 16.9 0.0 0.0087 15.7 0.0 1.6 1 0 0 1 1 1 1 NACHT domain TPR_8 PF13181.1 KLO17087.1 - 0.015 15.0 10.3 0.023 14.4 0.6 4.8 5 1 0 5 5 4 0 Tetratricopeptide repeat Miro PF08477.8 KLO17087.1 - 0.019 15.4 0.0 0.6 10.6 0.0 2.5 2 0 0 2 2 2 0 Miro-like protein DUF2225 PF09986.4 KLO17087.1 - 0.037 13.5 0.8 5.4 6.3 0.1 2.6 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2225) Glycoamylase PF10091.4 KLO17087.1 - 0.065 12.3 0.3 0.12 11.4 0.2 1.3 1 0 0 1 1 1 0 Putative glucoamylase DUF258 PF03193.11 KLO17087.1 - 0.074 12.2 0.0 0.17 11.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 ABC_tran PF00005.22 KLO17087.1 - 0.1 12.9 0.0 0.36 11.1 0.0 1.9 1 0 0 1 1 1 0 ABC transporter AAA_25 PF13481.1 KLO17087.1 - 0.11 11.9 0.0 0.4 10.0 0.0 2.0 1 0 0 1 1 1 0 AAA domain TPR_7 PF13176.1 KLO17087.1 - 0.82 9.6 0.0 0.82 9.6 0.0 5.7 7 0 0 7 7 6 0 Tetratricopeptide repeat TPR_16 PF13432.1 KLO17087.1 - 5.6 7.7 14.5 1.2 9.8 0.3 5.6 3 1 4 7 7 7 0 Tetratricopeptide repeat DSS1_SEM1 PF05160.8 KLO17088.1 - 9.6e-20 70.1 10.8 2.5e-19 68.8 7.5 1.6 1 1 0 1 1 1 1 DSS1/SEM1 family Peptidase_S13 PF02113.10 KLO17088.1 - 0.096 11.1 0.1 0.13 10.7 0.0 1.2 1 0 0 1 1 1 0 D-Ala-D-Ala carboxypeptidase 3 (S13) family Sugar_tr PF00083.19 KLO17089.1 - 9.6e-32 110.1 35.9 5.7e-18 64.7 7.3 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 KLO17089.1 - 6.3e-19 67.8 45.1 1.2e-13 50.5 16.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 KLO17089.1 - 0.0015 17.0 1.4 0.0015 17.0 1.0 3.1 1 1 2 3 3 3 2 MFS/sugar transport protein NACHT PF05729.7 KLO17090.1 - 1.1e-05 25.1 0.4 0.098 12.3 0.0 2.7 2 0 0 2 2 2 2 NACHT domain AAA_19 PF13245.1 KLO17090.1 - 4.6e-05 23.0 0.0 0.0001 21.9 0.0 1.5 1 0 0 1 1 1 1 Part of AAA domain AAA_22 PF13401.1 KLO17090.1 - 0.017 15.2 0.1 0.086 12.9 0.0 2.3 2 1 0 2 2 2 0 AAA domain MobB PF03205.9 KLO17090.1 - 0.072 12.7 0.0 0.12 12.0 0.0 1.3 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B CbiA PF01656.18 KLO17090.1 - 0.15 11.4 0.1 0.25 10.7 0.0 1.4 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain NACHT PF05729.7 KLO17091.1 - 9.8e-08 31.8 0.0 1.9e-07 30.8 0.0 1.5 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 KLO17091.1 - 0.00087 19.3 0.3 1.1 9.2 0.0 2.5 1 1 1 2 2 2 2 AAA ATPase domain AAA PF00004.24 KLO17091.1 - 0.042 14.0 0.0 0.092 12.9 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF443 PF04276.7 KLO17093.1 - 0.015 14.7 1.4 2.3 7.6 0.5 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF443) NACHT PF05729.7 KLO17094.1 - 1.7e-06 27.7 0.0 1.1e-05 25.1 0.0 2.1 1 1 0 1 1 1 1 NACHT domain AAA PF00004.24 KLO17094.1 - 9.7e-05 22.5 0.0 0.00024 21.2 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Pkinase PF00069.20 KLO17094.1 - 0.00018 20.7 0.0 0.00041 19.5 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain AAA_16 PF13191.1 KLO17094.1 - 0.005 16.8 0.0 0.018 15.0 0.0 1.9 1 0 0 1 1 1 1 AAA ATPase domain Pkinase_Tyr PF07714.12 KLO17094.1 - 0.033 13.2 0.0 0.055 12.5 0.0 1.3 1 0 0 1 1 1 0 Protein tyrosine kinase AAA_25 PF13481.1 KLO17094.1 - 0.14 11.5 0.2 2.1 7.7 0.1 2.7 2 1 0 2 2 2 0 AAA domain F-box-like PF12937.2 KLO17096.1 - 0.00015 21.3 2.0 0.00015 21.3 1.4 2.3 2 0 0 2 2 2 1 F-box-like F-box-like PF12937.2 KLO17097.1 - 4.7e-05 23.0 1.0 0.15 11.8 0.1 2.6 2 0 0 2 2 2 2 F-box-like Methyltransf_25 PF13649.1 KLO17098.1 - 3.6e-05 24.0 0.2 0.00043 20.6 0.1 2.7 2 1 1 3 3 3 1 Methyltransferase domain Aldo_ket_red PF00248.16 KLO17099.1 - 2.9e-53 180.5 0.0 3.5e-53 180.2 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family NmrA PF05368.8 KLO17100.1 - 4.5e-11 42.4 0.0 6.9e-11 41.8 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 KLO17100.1 - 6.5e-09 36.0 0.0 1.7e-08 34.7 0.0 1.7 1 1 1 2 2 2 1 NADH(P)-binding Epimerase PF01370.16 KLO17100.1 - 1.4e-08 34.4 0.0 5.8e-08 32.4 0.0 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 KLO17100.1 - 4.5e-08 32.1 0.0 3e-07 29.4 0.0 2.1 2 1 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family Saccharop_dh PF03435.13 KLO17100.1 - 9.8e-05 21.4 0.0 0.00014 20.9 0.0 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase NAD_binding_4 PF07993.7 KLO17100.1 - 0.00085 18.3 0.1 0.0052 15.7 0.0 2.1 1 1 0 1 1 1 1 Male sterility protein Polysacc_synt_2 PF02719.10 KLO17100.1 - 0.011 14.6 0.1 0.046 12.6 0.0 2.0 1 1 1 2 2 2 0 Polysaccharide biosynthesis protein Semialdhyde_dh PF01118.19 KLO17100.1 - 0.014 15.6 0.0 0.027 14.7 0.0 1.5 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain TrkA_N PF02254.13 KLO17100.1 - 0.026 14.5 0.0 0.041 13.8 0.0 1.3 1 0 0 1 1 1 0 TrkA-N domain Ldh_1_N PF00056.18 KLO17100.1 - 0.093 12.5 0.5 0.65 9.8 0.0 2.5 2 1 1 3 3 3 0 lactate/malate dehydrogenase, NAD binding domain Epimerase PF01370.16 KLO17101.1 - 1.5e-11 44.2 0.0 2.5e-11 43.4 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 KLO17101.1 - 1.9e-06 28.0 0.2 2.8e-06 27.4 0.2 1.3 1 0 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 KLO17101.1 - 3e-06 26.6 0.1 4.6e-06 26.0 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family 3Beta_HSD PF01073.14 KLO17101.1 - 3.9e-05 22.4 0.0 0.0001 21.0 0.0 1.7 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 KLO17101.1 - 0.0003 19.8 0.0 0.0009 18.2 0.0 1.8 2 0 0 2 2 2 1 Male sterility protein Saccharop_dh PF03435.13 KLO17101.1 - 0.0043 16.0 0.1 0.0062 15.5 0.1 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase Shikimate_DH PF01488.15 KLO17101.1 - 0.0089 16.1 0.0 0.016 15.2 0.0 1.5 1 1 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Semialdhyde_dh PF01118.19 KLO17101.1 - 0.028 14.6 0.0 0.068 13.4 0.0 1.7 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Ldh_1_N PF00056.18 KLO17101.1 - 0.13 12.1 1.3 1.3 8.8 0.0 2.6 2 1 0 2 2 2 0 lactate/malate dehydrogenase, NAD binding domain WD40 PF00400.27 KLO17102.1 - 2.7e-26 90.4 1.8 2.2e-08 33.6 0.1 5.3 5 0 0 5 5 5 4 WD domain, G-beta repeat eIF2A PF08662.6 KLO17102.1 - 0.017 14.8 0.0 0.49 10.0 0.0 2.6 2 1 0 2 2 2 0 Eukaryotic translation initiation factor eIF2A FA_hydroxylase PF04116.8 KLO17103.1 - 8.9e-13 48.6 35.2 2.9e-12 47.0 21.1 2.3 2 0 0 2 2 2 2 Fatty acid hydroxylase superfamily DUF1295 PF06966.7 KLO17104.1 - 1.7e-46 158.4 0.1 2.1e-46 158.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) Steroid_dh PF02544.11 KLO17104.1 - 7.2e-05 22.5 0.8 0.00017 21.3 0.1 1.8 2 0 0 2 2 2 1 3-oxo-5-alpha-steroid 4-dehydrogenase PEMT PF04191.8 KLO17104.1 - 0.0028 17.7 0.0 0.0099 15.9 0.0 2.0 1 1 0 1 1 1 1 Phospholipid methyltransferase ICMT PF04140.9 KLO17104.1 - 0.0077 16.4 0.2 0.017 15.3 0.0 1.7 2 0 0 2 2 2 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family ERG4_ERG24 PF01222.12 KLO17104.1 - 0.037 12.5 0.3 0.15 10.5 0.2 2.0 1 1 0 1 1 1 0 Ergosterol biosynthesis ERG4/ERG24 family F-box-like PF12937.2 KLO17105.1 - 1.7e-05 24.4 0.1 5.5e-05 22.7 0.1 2.0 1 0 0 1 1 1 1 F-box-like F-box-like PF12937.2 KLO17106.1 - 1.3e-05 24.7 0.1 4e-05 23.2 0.1 1.9 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.2 KLO17106.1 - 0.058 13.0 2.2 2 8.1 0.1 3.6 2 1 1 3 3 3 0 Leucine Rich repeats (2 copies) Complex1_LYR PF05347.10 KLO17107.1 - 4.6e-14 51.9 1.1 7.5e-14 51.2 0.1 1.8 2 0 0 2 2 2 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 KLO17107.1 - 1e-13 51.2 0.3 1.8e-13 50.4 0.2 1.5 1 1 0 1 1 1 1 Complex1_LYR-like Complex1_LYR_2 PF13233.1 KLO17107.1 - 0.00059 20.2 0.3 0.00076 19.9 0.2 1.2 1 0 0 1 1 1 1 Complex1_LYR-like RhoGAP PF00620.22 KLO17108.1 - 1.8e-39 134.7 0.0 4.1e-39 133.6 0.0 1.6 1 0 0 1 1 1 1 RhoGAP domain RasGEF PF00617.14 KLO17108.1 - 3.7e-11 43.1 0.0 1.7e-08 34.3 0.0 2.9 3 0 0 3 3 3 2 RasGEF domain PH_9 PF15410.1 KLO17108.1 - 1e-05 25.6 0.0 2.7e-05 24.3 0.0 1.7 1 0 0 1 1 1 1 Pleckstrin homology domain PH PF00169.24 KLO17108.1 - 0.00012 22.2 0.1 0.011 15.9 0.0 2.5 2 0 0 2 2 2 1 PH domain RasGEF_N PF00618.15 KLO17108.1 - 0.00056 19.9 0.1 0.0088 16.1 0.0 2.9 1 1 0 1 1 1 1 RasGEF N-terminal motif Glyco_transf_22 PF03901.12 KLO17109.1 - 1.9e-32 112.8 20.2 2.5e-32 112.4 14.0 1.1 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family Ala_racemase_N PF01168.15 KLO17110.1 - 1.4e-37 129.3 0.0 1.3e-18 67.3 0.0 2.1 2 0 0 2 2 2 2 Alanine racemase, N-terminal domain UPF0014 PF03649.8 KLO17111.1 - 9.5e-39 133.0 13.8 1.3e-38 132.6 9.6 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0014) FtsX PF02687.16 KLO17111.1 - 0.00076 19.2 4.5 0.00076 19.2 3.1 3.1 2 2 0 2 2 2 1 FtsX-like permease family UPF0220 PF05255.6 KLO17111.1 - 0.18 11.0 3.9 0.14 11.3 0.5 2.3 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0220) BPD_transp_1 PF00528.17 KLO17111.1 - 1.3 8.5 17.7 43 3.5 12.3 2.3 1 1 0 1 1 1 0 Binding-protein-dependent transport system inner membrane component IncA PF04156.9 KLO17111.1 - 2.4 7.7 5.8 2.5 7.6 0.4 2.9 2 1 0 2 2 2 0 IncA protein Pkinase PF00069.20 KLO17113.1 - 5.2e-41 140.5 0.0 1.2e-27 96.7 0.0 4.1 4 0 0 4 4 4 3 Protein kinase domain Pkinase_Tyr PF07714.12 KLO17113.1 - 1.6e-25 89.6 0.1 1.9e-20 73.0 0.0 3.2 3 0 0 3 3 3 3 Protein tyrosine kinase APH PF01636.18 KLO17113.1 - 0.0035 17.0 0.1 0.011 15.5 0.0 1.7 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.1 KLO17113.1 - 0.0064 15.4 0.0 1.4 7.8 0.0 2.2 2 0 0 2 2 2 2 Kinase-like RIO1 PF01163.17 KLO17113.1 - 0.12 11.6 0.1 0.25 10.6 0.1 1.4 1 0 0 1 1 1 0 RIO1 family SPRY PF00622.23 KLO17114.1 - 1.9e-07 31.2 0.0 5.4e-07 29.7 0.0 1.8 1 1 0 1 1 1 1 SPRY domain DASH_Hsk3 PF08227.6 KLO17115.1 - 0.63 10.2 4.6 7.2 6.8 0.1 2.8 2 0 0 2 2 2 0 DASH complex subunit Hsk3 like DUF972 PF06156.8 KLO17115.1 - 1.1 9.6 20.5 0.34 11.2 6.8 3.2 2 0 0 2 2 2 0 Protein of unknown function (DUF972) DMPK_coil PF08826.5 KLO17115.1 - 2.1 8.2 22.5 3.1 7.7 3.2 3.7 3 0 0 3 3 3 0 DMPK coiled coil domain like FUSC PF04632.7 KLO17115.1 - 2.8 6.2 7.7 4.4 5.6 5.3 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family GAS PF13851.1 KLO17115.1 - 4.1 6.5 32.0 0.042 13.0 8.2 3.2 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding WXG100 PF06013.7 KLO17115.1 - 4.7 7.2 15.0 12 5.9 1.1 4.3 3 1 0 3 3 3 0 Proteins of 100 residues with WXG Tropomyosin_1 PF12718.2 KLO17115.1 - 7.3 6.4 35.1 11 5.9 10.1 2.6 1 1 1 2 2 2 0 Tropomyosin like zf-MYND PF01753.13 KLO17117.1 - 1.9e-08 34.0 9.0 4.2e-08 32.9 6.3 1.6 1 0 0 1 1 1 1 MYND finger F-box-like PF12937.2 KLO17118.1 - 0.00052 19.6 0.0 0.056 13.1 0.0 2.7 2 0 0 2 2 2 2 F-box-like LRR_8 PF13855.1 KLO17118.1 - 0.1 12.3 3.9 0.27 11.0 0.0 3.3 4 0 0 4 4 4 0 Leucine rich repeat PrpF PF04303.8 KLO17119.1 - 9.1e-72 241.8 0.0 1.2e-71 241.4 0.0 1.1 1 0 0 1 1 1 1 PrpF protein Pkinase PF00069.20 KLO17120.1 - 3.7e-65 219.6 0.0 5.1e-65 219.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KLO17120.1 - 1.9e-37 128.7 0.0 2.5e-37 128.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KLO17120.1 - 1.8e-07 30.4 0.0 2.7e-07 29.8 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 KLO17120.1 - 0.0047 16.6 0.3 0.0084 15.8 0.2 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 KLO17120.1 - 0.01 14.8 0.1 0.027 13.5 0.1 1.6 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family PKD_channel PF08016.7 KLO17121.1 - 0.001 17.6 1.2 0.001 17.6 0.8 3.1 3 0 0 3 3 3 2 Polycystin cation channel CDC27 PF09507.5 KLO17123.1 - 2e-35 122.8 39.1 3.4e-35 122.1 27.1 1.4 1 0 0 1 1 1 1 DNA polymerase subunit Cdc27 DEAD PF00270.24 KLO17125.1 - 4.4e-38 130.4 0.0 2e-37 128.2 0.0 2.0 1 1 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KLO17125.1 - 1.9e-21 75.6 0.0 4.1e-21 74.6 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 KLO17125.1 - 2.8e-10 40.3 0.1 9e-10 38.6 0.0 1.9 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit SNF2_N PF00176.18 KLO17125.1 - 0.0078 15.0 0.0 0.012 14.3 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain AAA_19 PF13245.1 KLO17125.1 - 0.018 14.8 0.1 0.043 13.5 0.1 1.7 1 0 0 1 1 1 0 Part of AAA domain Flavi_DEAD PF07652.9 KLO17125.1 - 0.029 14.1 0.0 0.07 12.8 0.0 1.6 1 0 0 1 1 1 0 Flavivirus DEAD domain AAA_22 PF13401.1 KLO17125.1 - 0.11 12.6 0.6 2.4 8.2 0.0 2.7 3 0 0 3 3 3 0 AAA domain YscJ_FliF_C PF08345.6 KLO17126.1 - 0.021 14.7 0.2 0.021 14.7 0.1 2.6 3 0 0 3 3 3 0 Flagellar M-ring protein C-terminal Myb_DNA-binding PF00249.26 KLO17126.1 - 0.28 11.2 0.9 1.3 9.1 0.7 2.1 1 1 0 1 1 1 0 Myb-like DNA-binding domain Actin PF00022.14 KLO17127.1 - 7.8e-88 294.5 0.0 1.1e-87 294.0 0.0 1.1 1 0 0 1 1 1 1 Actin zf-MYND PF01753.13 KLO17128.1 - 2e-10 40.3 16.1 4e-10 39.3 11.2 1.5 1 0 0 1 1 1 1 MYND finger zf-Mss51 PF13824.1 KLO17128.1 - 0.047 13.5 8.3 0.14 12.0 5.7 1.8 1 0 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 APG17 PF04108.7 KLO17130.1 - 7.9e-35 120.4 4.8 2.3e-34 118.9 3.3 1.7 1 1 0 1 1 1 1 Autophagy protein Apg17 DUF869 PF05911.6 KLO17130.1 - 0.0028 15.9 2.3 0.0038 15.5 1.6 1.2 1 0 0 1 1 1 1 Plant protein of unknown function (DUF869) DUF1664 PF07889.7 KLO17130.1 - 0.056 13.2 5.6 1.1 9.0 0.1 3.6 1 1 3 4 4 4 0 Protein of unknown function (DUF1664) Bacillus_HBL PF05791.6 KLO17130.1 - 0.19 11.0 3.1 4.4 6.6 0.0 2.7 3 0 0 3 3 3 0 Bacillus haemolytic enterotoxin (HBL) CENP-F_leu_zip PF10473.4 KLO17130.1 - 0.2 11.5 7.5 0.039 13.8 2.0 2.2 2 1 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 TMF_TATA_bd PF12325.3 KLO17130.1 - 0.86 9.3 8.1 0.48 10.1 0.2 3.4 2 1 1 3 3 3 0 TATA element modulatory factor 1 TATA binding IncA PF04156.9 KLO17130.1 - 8 6.0 16.7 0.93 9.0 4.5 3.1 3 1 1 4 4 4 0 IncA protein CAF-1_p150 PF11600.3 KLO17132.1 - 8.8 5.6 6.9 13 5.1 4.8 1.1 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal DASH_Ask1 PF08655.5 KLO17134.1 - 2.7e-22 78.3 0.1 5.2e-22 77.4 0.1 1.5 1 0 0 1 1 1 1 DASH complex subunit Ask1 Rad9 PF04139.8 KLO17135.1 - 1e-46 159.1 0.1 1.4e-46 158.7 0.0 1.1 1 0 0 1 1 1 1 Rad9 Rad1 PF02144.11 KLO17135.1 - 0.00024 19.9 0.2 0.0029 16.4 0.1 2.1 2 0 0 2 2 2 1 Repair protein Rad1/Rec1/Rad17 Rep_fac_C PF08542.6 KLO17136.1 - 6.5e-22 77.3 0.3 1.7e-21 76.0 0.0 1.8 2 0 0 2 2 2 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.1 KLO17136.1 - 3e-14 52.9 0.0 7e-14 51.8 0.0 1.6 1 0 0 1 1 1 1 DNA polymerase III, delta subunit DNA_pol3_delta PF06144.8 KLO17136.1 - 1.3e-05 24.8 1.6 2e-05 24.1 1.1 1.3 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA PF00004.24 KLO17136.1 - 3.5e-05 23.9 1.5 0.00012 22.2 1.0 1.9 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_10 PF12846.2 KLO17136.1 - 0.0045 16.4 0.2 0.081 12.3 0.0 2.0 1 1 0 2 2 2 1 AAA-like domain AAA_16 PF13191.1 KLO17136.1 - 0.0075 16.2 0.5 0.16 11.9 0.0 2.3 1 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 KLO17136.1 - 0.0084 16.2 1.1 0.1 12.7 0.7 2.4 1 1 0 1 1 1 1 AAA domain Rad17 PF03215.10 KLO17136.1 - 0.015 14.0 0.0 0.036 12.7 0.0 1.7 1 1 1 2 2 2 0 Rad17 cell cycle checkpoint protein Sigma54_activ_2 PF14532.1 KLO17136.1 - 0.015 15.3 0.3 0.13 12.2 0.1 2.4 2 0 0 2 2 2 0 Sigma-54 interaction domain RuvB_N PF05496.7 KLO17136.1 - 0.017 14.1 0.1 4.9 6.1 0.0 2.9 2 1 1 3 3 3 0 Holliday junction DNA helicase ruvB N-terminus SNF2_N PF00176.18 KLO17136.1 - 0.022 13.5 0.1 0.03 13.0 0.0 1.2 1 0 0 1 1 1 0 SNF2 family N-terminal domain AAA_33 PF13671.1 KLO17136.1 - 0.057 13.2 0.4 0.39 10.5 0.1 2.2 2 1 0 2 2 2 0 AAA domain Bac_DnaA PF00308.13 KLO17136.1 - 0.2 11.2 2.4 1.5 8.3 1.6 2.2 1 1 0 1 1 1 0 Bacterial dnaA protein WD40 PF00400.27 KLO17137.1 - 4.9e-16 57.9 13.3 0.015 15.1 0.0 5.4 5 0 0 5 5 5 5 WD domain, G-beta repeat CHU_C PF13585.1 KLO17138.1 - 0.076 12.9 0.6 7.6 6.4 0.0 2.2 2 0 0 2 2 2 0 C-terminal domain of CHU protein family But2 PF09792.4 KLO17139.1 - 0.0004 20.1 0.0 0.00073 19.3 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin 3 binding protein But2 C-terminal domain DUF3328 PF11807.3 KLO17140.1 - 1.2e-23 83.9 0.0 1.7e-23 83.4 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) DUF1422 PF07226.6 KLO17140.1 - 0.034 13.8 0.0 0.05 13.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1422) DUF3328 PF11807.3 KLO17141.1 - 1.1e-15 57.9 0.1 2.1e-15 56.9 0.0 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF3328) PhrC_PhrF PF11131.3 KLO17141.1 - 0.38 10.3 1.4 0.74 9.4 0.9 1.4 1 0 0 1 1 1 0 Rap-phr extracellular signalling Glyco_hydro_67N PF03648.9 KLO17142.1 - 0.017 15.1 0.0 0.11 12.5 0.0 2.2 2 0 0 2 2 2 0 Glycosyl hydrolase family 67 N-terminus MMR_HSR1 PF01926.18 KLO17142.1 - 0.081 12.8 0.0 0.23 11.4 0.0 1.7 1 0 0 1 1 1 0 50S ribosome-binding GTPase DUF4662 PF15578.1 KLO17142.1 - 0.19 11.3 0.1 27 4.2 0.0 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4662) AIG2 PF06094.7 KLO17143.1 - 8.5e-08 32.6 0.0 1.3e-07 32.0 0.0 1.4 1 0 0 1 1 1 1 AIG2-like family ECH PF00378.15 KLO17144.1 - 8.4e-23 80.7 0.0 1.2e-22 80.2 0.0 1.2 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family Plectin PF00681.15 KLO17144.1 - 0.07 12.6 0.0 0.17 11.3 0.0 1.6 1 0 0 1 1 1 0 Plectin repeat Response_reg PF00072.19 KLO17145.1 - 1.9e-17 63.2 0.0 1.5e-16 60.4 0.0 2.4 2 1 0 2 2 2 1 Response regulator receiver domain HATPase_c PF02518.21 KLO17145.1 - 3.3e-16 58.9 0.1 6.4e-16 58.0 0.1 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.20 KLO17145.1 - 8.8e-15 54.4 0.1 2.2e-14 53.1 0.0 1.8 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain GAF_3 PF13492.1 KLO17145.1 - 4.1e-05 23.6 0.0 0.0061 16.6 0.0 3.4 3 1 0 3 3 3 1 GAF domain GAF PF01590.21 KLO17145.1 - 0.0001 22.4 0.1 0.0025 17.9 0.0 3.0 2 1 0 2 2 2 1 GAF domain OpgC_C PF10129.4 KLO17145.1 - 1.5 7.4 0.2 2.4 6.7 0.1 1.2 1 0 0 1 1 1 0 OpgC protein Cytochrom_B561 PF03188.11 KLO17146.1 - 3.6e-09 36.5 11.3 3.6e-09 36.5 7.8 2.5 1 1 1 2 2 2 1 Eukaryotic cytochrome b561 NPDC1 PF06809.6 KLO17146.1 - 0.027 13.2 0.0 0.043 12.6 0.0 1.2 1 0 0 1 1 1 0 Neural proliferation differentiation control-1 protein (NPDC1) PepSY_TM_1 PF13172.1 KLO17146.1 - 0.039 13.7 0.3 0.039 13.7 0.2 3.9 4 0 0 4 4 4 0 PepSY-associated TM helix PilX_N PF14341.1 KLO17146.1 - 0.63 9.7 3.0 24 4.6 0.0 2.5 2 0 0 2 2 2 0 PilX N-terminal DUF2392 PF10288.4 KLO17147.1 - 2.2e-12 47.2 0.0 4.1e-12 46.3 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2392) PRK PF00485.13 KLO17148.1 - 1.2e-49 168.5 0.0 1.8e-49 167.9 0.0 1.2 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family UPRTase PF14681.1 KLO17148.1 - 2.1e-47 160.9 0.0 8.3e-45 152.5 0.0 2.3 2 0 0 2 2 2 2 Uracil phosphoribosyltransferase AAA_18 PF13238.1 KLO17148.1 - 3.7e-06 27.2 0.0 9.4e-06 25.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 KLO17148.1 - 4.1e-05 24.3 0.0 0.00017 22.3 0.0 2.2 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 KLO17148.1 - 0.00094 19.0 0.0 0.0027 17.6 0.0 1.8 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 KLO17148.1 - 0.0014 17.7 0.0 0.0029 16.7 0.0 1.5 1 0 0 1 1 1 1 Zeta toxin CoaE PF01121.15 KLO17148.1 - 0.028 13.8 0.1 0.96 8.8 0.1 2.4 2 0 0 2 2 2 0 Dephospho-CoA kinase AAA_14 PF13173.1 KLO17148.1 - 0.069 13.0 0.0 1.3 8.9 0.0 3.1 3 1 0 3 3 3 0 AAA domain UPF0079 PF02367.12 KLO17148.1 - 0.15 11.6 0.0 0.38 10.3 0.0 1.6 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 UPF0126 PF03458.8 KLO17148.1 - 1.9 8.1 6.1 1.1 8.9 2.5 1.9 2 0 0 2 2 2 0 UPF0126 domain Cyclin_N PF00134.18 KLO17149.1 - 7.9e-43 145.0 0.1 1.3e-41 141.0 0.1 2.1 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 KLO17149.1 - 2.6e-25 88.6 0.0 4.8e-25 87.7 0.0 1.4 1 0 0 1 1 1 1 Cyclin, C-terminal domain p450 PF00067.17 KLO17150.1 - 6.5e-63 212.8 0.0 3e-62 210.6 0.0 1.8 1 1 0 1 1 1 1 Cytochrome P450 UbiA PF01040.13 KLO17151.1 - 1.3e-15 57.3 13.5 1.9e-15 56.8 9.4 1.2 1 0 0 1 1 1 1 UbiA prenyltransferase family zf-C3HC PF07967.8 KLO17152.1 - 2e-26 92.3 0.1 1.3e-22 80.0 0.1 2.4 2 0 0 2 2 2 2 C3HC zinc finger-like Rsm1 PF08600.5 KLO17152.1 - 2.9e-15 55.8 5.7 9.3e-11 41.4 0.0 3.1 3 0 0 3 3 3 2 Rsm1-like P53_C PF11619.3 KLO17152.1 - 0.02 14.6 0.0 0.042 13.6 0.0 1.5 1 0 0 1 1 1 0 Transcription factor P53 - C terminal domain DUF2611 PF11022.3 KLO17152.1 - 0.22 11.6 1.3 1.2 9.2 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2611) DM PF00751.13 KLO17152.1 - 0.44 10.1 2.5 21 4.7 0.4 2.5 2 0 0 2 2 2 0 DM DNA binding domain DUF2370 PF10176.4 KLO17153.1 - 9.3e-68 228.0 0.0 1.8e-67 227.1 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2370) Methyltransf_23 PF13489.1 KLO17154.1 - 4.9e-08 32.8 0.0 1.1e-07 31.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KLO17154.1 - 0.00028 21.3 0.0 0.0013 19.2 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain MetW PF07021.7 KLO17154.1 - 0.0054 16.1 0.0 0.0086 15.4 0.0 1.2 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_25 PF13649.1 KLO17154.1 - 0.0068 16.7 0.0 0.018 15.3 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KLO17154.1 - 0.007 15.9 0.1 0.018 14.6 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 KLO17154.1 - 0.013 15.9 0.0 0.72 10.3 0.0 2.4 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_32 PF13679.1 KLO17154.1 - 0.064 12.9 0.0 0.14 11.8 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_18 PF12847.2 KLO17154.1 - 0.095 13.2 0.0 0.19 12.3 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain ATP_synt_H PF05493.8 KLO17155.1 - 2.7e-19 69.0 6.8 3.3e-19 68.7 4.7 1.0 1 0 0 1 1 1 1 ATP synthase subunit H Intg_mem_TP0381 PF09529.5 KLO17155.1 - 0.17 11.0 2.0 0.18 10.9 1.4 1.0 1 0 0 1 1 1 0 Integral membrane protein (intg_mem_TP0381) UPF0197 PF05251.7 KLO17155.1 - 0.84 9.9 3.1 1.5 9.1 2.1 1.6 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0197) DUF4131 PF13567.1 KLO17155.1 - 0.94 8.8 6.0 1.1 8.5 4.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) HLH PF00010.21 KLO17156.1 - 1.6e-05 24.4 0.0 3.6e-05 23.3 0.0 1.6 1 1 0 1 1 1 1 Helix-loop-helix DNA-binding domain Neur_chan_memb PF02932.11 KLO17156.1 - 1.6 8.5 3.8 1.7 8.4 0.1 2.2 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region NUDIX PF00293.23 KLO17157.1 - 9.3e-14 51.2 0.1 1.4e-13 50.6 0.1 1.2 1 0 0 1 1 1 1 NUDIX domain Zip PF02535.17 KLO17158.1 - 3e-50 171.0 11.8 6e-43 147.0 2.6 2.1 1 1 1 2 2 2 2 ZIP Zinc transporter PrgI PF12666.2 KLO17158.1 - 5.3 7.2 8.0 20 5.4 0.0 4.1 4 0 0 4 4 4 0 PrgI family protein HD PF01966.17 KLO17159.1 - 0.00018 21.5 0.3 0.00077 19.4 0.2 2.0 1 1 0 1 1 1 1 HD domain Epimerase PF01370.16 KLO17162.1 - 2.8e-18 66.2 0.4 2e-17 63.4 0.3 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 KLO17162.1 - 6.5e-14 51.2 0.3 2.8e-13 49.2 0.2 1.9 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 KLO17162.1 - 3.4e-11 43.4 0.0 1.1e-10 41.7 0.0 1.9 1 1 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 KLO17162.1 - 6.9e-11 41.5 0.1 0.00018 20.5 0.0 2.1 1 1 1 2 2 2 2 Male sterility protein NmrA PF05368.8 KLO17162.1 - 5.7e-10 38.8 0.0 4.5e-09 35.9 0.1 2.0 2 0 0 2 2 2 1 NmrA-like family Polysacc_synt_2 PF02719.10 KLO17162.1 - 3e-05 23.0 0.5 7.4e-05 21.7 0.3 1.6 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein adh_short PF00106.20 KLO17162.1 - 0.01 15.7 0.0 0.021 14.7 0.0 1.5 1 0 0 1 1 1 0 short chain dehydrogenase Glyco_transf_20 PF00982.16 KLO17163.1 - 5.5e-184 612.0 0.0 1.3e-141 472.3 0.0 2.0 2 0 0 2 2 2 2 Glycosyltransferase family 20 Glycos_transf_1 PF00534.15 KLO17163.1 - 0.0064 15.9 0.6 4.7 6.6 0.1 2.8 2 1 0 2 2 2 2 Glycosyl transferases group 1 Epimerase PF01370.16 KLO17164.1 - 1.4e-16 60.6 0.0 1.5e-15 57.3 0.0 2.0 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 KLO17164.1 - 8.9e-13 47.5 0.0 2e-12 46.3 0.0 1.5 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 KLO17164.1 - 2.2e-12 47.3 0.0 5.8e-12 45.9 0.0 1.7 1 1 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 KLO17164.1 - 1.8e-08 33.6 0.0 1.4e-05 24.1 0.0 2.2 1 1 1 2 2 2 2 Male sterility protein NmrA PF05368.8 KLO17164.1 - 1e-06 28.2 0.0 1.5e-06 27.6 0.0 1.4 1 0 0 1 1 1 1 NmrA-like family adh_short PF00106.20 KLO17164.1 - 7.6e-05 22.6 0.1 0.0002 21.2 0.1 1.8 1 1 0 1 1 1 1 short chain dehydrogenase Polysacc_synt_2 PF02719.10 KLO17164.1 - 0.00057 18.8 0.0 0.034 13.0 0.0 2.3 1 1 1 2 2 2 1 Polysaccharide biosynthesis protein DapB_N PF01113.15 KLO17164.1 - 0.023 14.6 0.0 0.049 13.5 0.0 1.5 1 1 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus KR PF08659.5 KLO17164.1 - 0.023 14.3 0.4 0.063 12.9 0.3 1.7 1 1 0 1 1 1 0 KR domain COesterase PF00135.23 KLO17165.1 - 1.5e-97 327.5 3.5 1.1e-96 324.6 2.4 1.8 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 KLO17165.1 - 1.9e-10 40.6 0.2 9.3e-10 38.4 0.2 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold PPR_3 PF13812.1 KLO17166.1 - 0.86 10.0 8.8 15 6.2 0.0 4.7 7 0 0 7 7 7 0 Pentatricopeptide repeat domain An_peroxidase PF03098.10 KLO17167.1 - 7.5e-65 219.2 0.0 1.2e-62 212.0 0.0 2.2 1 1 0 1 1 1 1 Animal haem peroxidase p450 PF00067.17 KLO17167.1 - 1.2e-07 30.6 0.0 1.1e-06 27.4 0.0 2.1 2 0 0 2 2 2 1 Cytochrome P450 Pkinase PF00069.20 KLO17168.1 - 1.1e-40 139.4 0.0 1.6e-40 138.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KLO17168.1 - 3.5e-38 131.1 0.0 4.8e-38 130.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KLO17168.1 - 8.4e-06 24.9 0.0 1.4e-05 24.2 0.0 1.2 1 0 0 1 1 1 1 Kinase-like TMF_TATA_bd PF12325.3 KLO17169.1 - 0.052 13.2 1.2 2.4 7.8 0.2 2.1 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding BRO1 PF03097.13 KLO17172.1 - 2e-87 293.4 0.1 3.3e-87 292.6 0.1 1.4 1 0 0 1 1 1 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.1 KLO17172.1 - 1.3e-67 227.9 6.6 2.2e-67 227.1 4.6 1.4 1 0 0 1 1 1 1 ALIX V-shaped domain binding to HIV SPX PF03105.14 KLO17172.1 - 0.0028 17.4 3.7 0.0069 16.2 2.7 1.5 1 1 0 1 1 1 1 SPX domain Xpo1 PF08389.7 KLO17173.1 - 7.7e-21 74.5 0.7 2.2e-18 66.5 0.0 4.3 4 1 0 4 4 4 1 Exportin 1-like protein HEAT PF02985.17 KLO17173.1 - 0.00073 19.4 0.4 0.029 14.4 0.0 3.6 3 0 0 3 3 3 1 HEAT repeat HEAT_EZ PF13513.1 KLO17173.1 - 0.0025 18.2 2.1 4 8.0 0.1 4.7 5 0 0 5 5 5 1 HEAT-like repeat IBN_N PF03810.14 KLO17173.1 - 0.025 14.4 0.0 1.9 8.4 0.0 3.6 3 0 0 3 3 3 0 Importin-beta N-terminal domain HEAT_2 PF13646.1 KLO17173.1 - 0.042 14.1 0.7 1.3 9.3 0.0 3.2 2 1 0 2 2 2 0 HEAT repeats UME PF08064.8 KLO17173.1 - 0.051 13.5 1.0 0.28 11.1 0.2 2.7 2 0 0 2 2 2 0 UME (NUC010) domain Cullin PF00888.17 KLO17174.1 - 3.8e-152 507.8 0.0 4.8e-152 507.5 0.0 1.1 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.4 KLO17174.1 - 4.8e-28 96.7 3.9 8.2e-28 96.0 1.6 2.3 2 0 0 2 2 2 1 Cullin protein neddylation domain Penicillinase_R PF03965.11 KLO17174.1 - 0.056 13.5 0.0 0.16 12.0 0.0 1.9 1 0 0 1 1 1 0 Penicillinase repressor BCDHK_Adom3 PF10436.4 KLO17175.1 - 1.2e-36 125.6 0.0 1.7e-36 125.2 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.21 KLO17175.1 - 2e-14 53.2 0.0 9.1e-09 35.0 0.0 2.4 2 0 0 2 2 2 2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.1 KLO17175.1 - 0.00015 21.4 0.0 0.00024 20.7 0.0 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Viral_DNA_Zn_bi PF03728.8 KLO17175.1 - 0.05 13.7 0.0 0.091 12.8 0.0 1.3 1 0 0 1 1 1 0 Viral DNA-binding protein, zinc binding domain ATP-synt_ab PF00006.20 KLO17176.1 - 3.6e-113 376.3 0.0 5.1e-113 375.8 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 KLO17176.1 - 2.9e-21 76.0 0.6 6.1e-21 74.9 0.4 1.6 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 KLO17176.1 - 5e-14 52.2 3.4 1.4e-13 50.8 2.4 1.8 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain E2R135 PF11570.3 KLO17176.1 - 0.057 13.5 0.0 0.13 12.3 0.0 1.5 1 0 0 1 1 1 0 Coiled-coil receptor-binding R-domain of colicin E2 AAA_14 PF13173.1 KLO17176.1 - 0.1 12.5 0.0 0.34 10.7 0.0 1.9 2 0 0 2 2 2 0 AAA domain COG7 PF10191.4 KLO17177.1 - 0.027 12.4 0.7 0.032 12.1 0.5 1.1 1 0 0 1 1 1 0 Golgi complex component 7 (COG7) DnaJ PF00226.26 KLO17178.1 - 4.4e-25 87.1 1.0 7.1e-25 86.5 0.7 1.4 1 0 0 1 1 1 1 DnaJ domain CTDII PF01556.13 KLO17178.1 - 4.6e-22 77.6 0.1 2.5e-19 68.9 0.0 3.0 3 0 0 3 3 3 1 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.14 KLO17178.1 - 3.4e-16 59.0 16.4 6.2e-16 58.1 11.4 1.5 1 0 0 1 1 1 1 DnaJ central domain HypA PF01155.14 KLO17178.1 - 5e-05 22.9 1.7 0.24 11.1 0.0 2.3 2 0 0 2 2 2 2 Hydrogenase expression/synthesis hypA family Lar_restr_allev PF14354.1 KLO17178.1 - 0.0063 16.7 7.0 1.6 9.0 0.1 2.8 1 1 1 2 2 2 2 Restriction alleviation protein Lar PADR1 PF08063.7 KLO17178.1 - 0.55 9.6 9.6 1.8 8.0 0.1 3.0 2 1 1 3 3 3 0 PADR1 (NUC008) domain DZR PF12773.2 KLO17178.1 - 1 9.2 10.9 45 3.9 7.6 2.3 1 1 0 1 1 1 0 Double zinc ribbon zf-C4_Topoisom PF01396.14 KLO17178.1 - 1 8.9 4.7 1 8.9 0.1 2.8 3 0 0 3 3 3 0 Topoisomerase DNA binding C4 zinc finger zf-ribbon_3 PF13248.1 KLO17178.1 - 3 7.1 7.9 0.38 10.0 2.3 2.0 2 0 0 2 2 2 0 zinc-ribbon domain zf-RING_3 PF14369.1 KLO17178.1 - 7.4 6.6 10.9 14 5.7 0.1 4.1 3 1 1 4 4 4 0 zinc-finger adh_short PF00106.20 KLO17179.1 - 1.1e-18 67.7 0.1 1.6e-18 67.2 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KLO17179.1 - 8.2e-13 48.4 0.4 1.5e-12 47.5 0.3 1.3 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 KLO17179.1 - 8.5e-09 35.5 0.0 1.3e-08 34.9 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 KLO17179.1 - 0.0004 19.9 0.1 0.00094 18.6 0.1 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family MoCF_biosynth PF00994.19 KLO17179.1 - 0.001 18.4 0.0 0.0019 17.6 0.0 1.7 1 0 0 1 1 1 1 Probable molybdopterin binding domain THF_DHG_CYH_C PF02882.14 KLO17179.1 - 0.029 13.4 0.0 0.049 12.6 0.0 1.3 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain NAD_binding_10 PF13460.1 KLO17179.1 - 0.054 13.4 0.7 0.12 12.3 0.5 1.8 1 1 0 1 1 1 0 NADH(P)-binding RasGAP PF00616.14 KLO17180.1 - 4.1e-53 179.9 0.3 1.4e-52 178.2 0.0 2.1 3 0 0 3 3 3 1 GTPase-activator protein for Ras-like GTPase RasGAP_C PF03836.10 KLO17180.1 - 1.4e-34 118.8 1.2 4.9e-34 117.0 0.8 2.0 1 0 0 1 1 1 1 RasGAP C-terminus Herpes_UL14 PF03580.9 KLO17180.1 - 0.077 12.7 6.4 0.03 14.1 1.9 2.1 2 0 0 2 2 2 0 Herpesvirus UL14-like protein DUF972 PF06156.8 KLO17180.1 - 0.62 10.4 8.4 2.4 8.5 0.1 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF972) Asp PF00026.18 KLO17181.1 - 1.4e-43 149.3 0.0 1.9e-43 148.9 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 KLO17181.1 - 2.8e-08 33.8 0.2 6.2e-08 32.7 0.2 1.6 1 0 0 1 1 1 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 KLO17181.1 - 0.013 15.9 0.3 0.15 12.5 0.2 2.7 1 1 0 1 1 1 0 Aspartyl protease LRR_4 PF12799.2 KLO17182.1 - 0.18 11.4 4.3 5.1 6.8 0.2 3.1 3 0 0 3 3 3 0 Leucine Rich repeats (2 copies) L1R_F9L PF02442.12 KLO17183.1 - 0.085 12.3 0.0 0.15 11.5 0.0 1.3 1 0 0 1 1 1 0 Lipid membrane protein of large eukaryotic DNA viruses F-box-like PF12937.2 KLO17184.1 - 1.8e-05 24.3 0.1 5.3e-05 22.8 0.1 1.9 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KLO17184.1 - 0.013 15.1 0.0 0.038 13.6 0.0 1.9 1 0 0 1 1 1 0 F-box domain Fungal_trans PF04082.13 KLO17186.1 - 7.7e-14 51.1 1.5 1.3e-13 50.4 1.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KLO17186.1 - 2.2e-08 33.8 6.9 4.7e-08 32.8 4.8 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Cellulase PF00150.13 KLO17187.1 - 1.1e-13 51.0 0.5 1.1e-13 51.0 0.3 1.4 2 0 0 2 2 2 1 Cellulase (glycosyl hydrolase family 5) SecE PF00584.15 KLO17187.1 - 0.023 14.2 0.0 0.05 13.1 0.0 1.6 1 0 0 1 1 1 0 SecE/Sec61-gamma subunits of protein translocation complex MnhB PF04039.8 KLO17193.1 - 0.051 13.6 1.9 0.077 13.0 0.7 1.7 1 1 1 2 2 2 0 Domain related to MnhB subunit of Na+/H+ antiporter ADH_zinc_N PF00107.21 KLO17194.1 - 1.4e-20 73.1 0.1 3.1e-20 72.0 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 KLO17194.1 - 1.1e-09 39.2 0.0 2.8e-09 37.9 0.0 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase STE3 PF02076.10 KLO17195.1 - 0.091 11.8 0.2 0.14 11.2 0.1 1.3 2 0 0 2 2 2 0 Pheromone A receptor LsmAD PF06741.8 KLO17196.1 - 5.8e-26 90.3 3.9 1.2e-25 89.3 2.7 1.6 1 0 0 1 1 1 1 LsmAD domain SM-ATX PF14438.1 KLO17196.1 - 1.1e-05 25.3 0.0 2.4e-05 24.1 0.0 1.6 1 0 0 1 1 1 1 Ataxin 2 SM domain LSM PF01423.17 KLO17196.1 - 0.15 11.6 0.0 0.28 10.7 0.0 1.4 1 0 0 1 1 1 0 LSM domain ADH_zinc_N PF00107.21 KLO17197.1 - 3.4e-19 68.6 0.1 6.3e-19 67.8 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 KLO17197.1 - 5.3e-09 37.0 0.0 1.1e-08 36.0 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase MIP PF00230.15 KLO17199.1 - 3.5e-34 118.2 7.2 5.4e-34 117.6 5.0 1.2 1 0 0 1 1 1 1 Major intrinsic protein SMC_hinge PF06470.8 KLO17202.1 - 1.8e-26 92.4 0.0 4.5e-26 91.1 0.0 1.8 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain SMC_N PF02463.14 KLO17202.1 - 0.00016 20.9 0.0 0.00016 20.9 0.0 3.1 1 1 1 2 2 2 2 RecF/RecN/SMC N terminal domain Mad3_BUB1_I PF08311.7 KLO17203.1 - 5.7e-24 84.3 0.9 5.7e-24 84.3 0.6 1.7 2 0 0 2 2 2 1 Mad3/BUB1 homology region 1 Pkinase PF00069.20 KLO17203.1 - 1.7e-19 70.0 0.0 2.9e-19 69.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KLO17203.1 - 7.6e-07 28.4 0.0 1.3e-06 27.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Ndc1_Nup PF09531.5 KLO17203.1 - 0.53 8.6 5.4 0.086 11.2 0.1 2.0 2 0 0 2 2 2 0 Nucleoporin protein Ndc1-Nup Tropomyosin PF00261.15 KLO17204.1 - 0.00022 20.4 11.0 0.00022 20.4 7.6 4.4 2 1 1 4 4 4 2 Tropomyosin Spc7 PF08317.6 KLO17204.1 - 0.0011 17.7 19.2 0.0011 17.7 13.3 3.0 1 1 2 3 3 3 2 Spc7 kinetochore protein GAS PF13851.1 KLO17204.1 - 0.0011 18.1 11.9 0.0011 18.1 8.3 3.8 1 1 3 4 4 3 1 Growth-arrest specific micro-tubule binding Reo_sigmaC PF04582.7 KLO17204.1 - 0.0039 16.4 4.9 0.0039 16.4 3.4 2.6 1 1 1 3 3 3 1 Reovirus sigma C capsid protein IncA PF04156.9 KLO17204.1 - 0.0072 15.9 16.1 0.0072 15.9 11.2 3.6 1 1 2 3 3 3 2 IncA protein CENP-F_leu_zip PF10473.4 KLO17204.1 - 0.075 12.8 61.5 0.085 12.7 16.0 4.7 1 1 2 3 3 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 FlaC_arch PF05377.6 KLO17204.1 - 0.24 11.3 0.1 0.24 11.3 0.1 5.2 5 1 1 7 7 7 0 Flagella accessory protein C (FlaC) Nup54 PF13874.1 KLO17204.1 - 0.32 10.6 38.1 0.21 11.2 4.5 4.0 2 2 1 3 3 3 0 Nucleoporin complex subunit 54 MtrB PF05440.7 KLO17204.1 - 0.39 10.7 1.4 2.2 8.3 0.1 2.8 2 1 1 3 3 3 0 Tetrahydromethanopterin S-methyltransferase subunit B Baculo_PEP_C PF04513.7 KLO17204.1 - 0.71 9.6 13.9 0.22 11.3 2.1 3.1 1 1 2 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Flagellin_N PF00669.15 KLO17204.1 - 1.3 8.8 18.1 2.6 7.8 1.9 4.0 2 1 3 5 5 5 0 Bacterial flagellin N-terminal helical region Filament PF00038.16 KLO17204.1 - 1.3 8.4 47.8 0.39 10.1 15.9 3.1 1 1 1 2 2 2 0 Intermediate filament protein DUF3610 PF12272.3 KLO17204.1 - 1.5 8.4 4.2 0.54 9.8 0.1 2.3 3 1 0 3 3 3 0 Protein of unknown function (DUF3610) Tropomyosin_1 PF12718.2 KLO17204.1 - 2 8.2 60.0 0.061 13.1 8.9 3.7 1 1 2 3 3 3 0 Tropomyosin like Alpha-amylase PF00128.19 KLO17207.1 - 7.5e-28 97.8 0.0 2.6e-27 96.0 0.0 1.7 1 1 0 1 1 1 1 Alpha amylase, catalytic domain Glyco_hydro_70 PF02324.11 KLO17207.1 - 2.2e-09 35.7 0.2 1.7e-05 22.8 0.1 3.0 3 0 0 3 3 3 3 Glycosyl hydrolase family 70 Sugar_tr PF00083.19 KLO17208.1 - 4.7e-82 275.9 19.4 5.5e-82 275.7 13.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KLO17208.1 - 2.9e-26 92.0 46.2 1e-23 83.6 18.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 KLO17208.1 - 0.0008 17.9 4.4 0.0008 17.9 3.0 3.2 2 2 1 3 3 3 2 MFS/sugar transport protein DUF4141 PF13605.1 KLO17210.1 - 0.021 14.0 0.5 0.081 12.1 0.4 2.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4141) DNA_pol_viral_N PF00242.12 KLO17210.1 - 3.5 6.5 4.6 4.4 6.2 3.2 1.0 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain Exo_endo_phos PF03372.18 KLO17211.1 - 1.3e-07 31.8 0.0 1.5e-07 31.6 0.0 1.1 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family RhoGEF PF00621.15 KLO17212.1 - 3.2e-33 115.1 0.1 5.2e-33 114.4 0.1 1.3 1 0 0 1 1 1 1 RhoGEF domain CNH PF00780.17 KLO17212.1 - 8.1e-31 107.4 0.0 1.2e-30 106.9 0.0 1.2 1 0 0 1 1 1 1 CNH domain PH_5 PF15405.1 KLO17212.1 - 3.2e-09 36.8 0.0 2.2e-08 34.1 0.0 2.3 2 0 0 2 2 2 1 Pleckstrin homology domain PH PF00169.24 KLO17212.1 - 2.2e-05 24.6 0.0 5.8e-05 23.2 0.0 1.8 1 0 0 1 1 1 1 PH domain GUB_WAK_bind PF13947.1 KLO17212.1 - 0.13 12.8 0.1 0.28 11.7 0.0 1.6 1 0 0 1 1 1 0 Wall-associated receptor kinase galacturonan-binding MFS_1 PF07690.11 KLO17213.1 - 4.5e-18 65.0 28.0 3.1e-17 62.3 14.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Nodulin-like PF06813.8 KLO17213.1 - 1.1e-10 41.1 0.6 2.9e-10 39.8 0.4 1.6 1 0 0 1 1 1 1 Nodulin-like DEAD PF00270.24 KLO17214.1 - 1.1e-40 138.9 0.0 2e-39 134.8 0.0 2.3 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KLO17214.1 - 9.4e-24 83.0 0.2 3.1e-23 81.4 0.1 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 KLO17214.1 - 0.0026 17.5 0.5 0.05 13.4 0.0 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Acetyltransf_3 PF13302.1 KLO17215.1 - 1.1e-12 48.3 0.0 8.1e-11 42.2 0.0 2.1 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 KLO17215.1 - 0.0019 18.1 0.0 2.3 8.1 0.0 2.3 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 KLO17215.1 - 0.0022 17.9 0.0 0.51 10.4 0.0 2.5 2 0 0 2 2 2 2 Acetyltransferase (GNAT) family Thioredoxin PF00085.15 KLO17216.1 - 2.6e-59 197.3 0.6 9.3e-29 99.1 0.0 2.5 2 0 0 2 2 2 2 Thioredoxin Thioredoxin_2 PF13098.1 KLO17216.1 - 2.5e-21 75.9 1.8 5.4e-10 39.4 0.1 3.1 3 0 0 3 3 3 2 Thioredoxin-like domain ERp29 PF07749.7 KLO17216.1 - 8.1e-21 74.4 1.3 8.1e-21 74.4 0.9 2.7 2 1 1 3 3 3 1 Endoplasmic reticulum protein ERp29, C-terminal domain Thioredoxin_7 PF13899.1 KLO17216.1 - 2e-15 56.5 0.2 4.8e-07 29.7 0.0 2.8 3 0 0 3 3 3 2 Thioredoxin-like Thioredoxin_8 PF13905.1 KLO17216.1 - 3.4e-14 52.7 0.2 9.1e-05 22.5 0.0 4.5 2 2 2 4 4 4 3 Thioredoxin-like Thioredoxin_6 PF13848.1 KLO17216.1 - 1.1e-11 44.9 0.6 0.00042 20.1 0.1 4.2 3 1 1 4 4 4 3 Thioredoxin-like domain AhpC-TSA PF00578.16 KLO17216.1 - 4.4e-09 36.0 3.2 0.00017 21.2 0.0 3.9 3 1 0 4 4 4 2 AhpC/TSA family Redoxin PF08534.5 KLO17216.1 - 8.7e-09 35.0 0.7 8.4e-05 22.1 0.0 2.5 2 0 0 2 2 2 2 Redoxin ERp29_N PF07912.8 KLO17216.1 - 4.5e-07 29.8 3.2 0.0091 15.9 0.0 2.6 3 0 0 3 3 3 2 ERp29, N-terminal domain Thioredoxin_9 PF14595.1 KLO17216.1 - 3.9e-05 23.2 2.8 0.023 14.2 0.0 3.2 3 1 0 3 3 3 2 Thioredoxin TraF PF13728.1 KLO17216.1 - 0.00047 19.7 2.7 0.64 9.4 0.0 3.0 3 1 0 3 3 3 2 F plasmid transfer operon protein Thioredoxin_3 PF13192.1 KLO17216.1 - 0.0014 18.3 2.4 0.25 11.1 0.0 3.1 3 0 0 3 3 3 1 Thioredoxin domain Thioredoxin_5 PF13743.1 KLO17216.1 - 0.0036 16.8 0.5 0.9 9.0 0.0 3.6 2 2 1 3 3 3 1 Thioredoxin Thioredoxin_4 PF13462.1 KLO17216.1 - 0.0083 16.1 10.8 0.26 11.2 0.1 4.2 3 2 2 5 5 5 1 Thioredoxin Glutaredoxin PF00462.19 KLO17216.1 - 0.023 14.7 3.0 1 9.3 0.2 3.2 2 2 0 2 2 2 0 Glutaredoxin HyaE PF07449.6 KLO17216.1 - 0.029 14.2 0.0 0.41 10.5 0.0 2.6 2 0 0 2 2 2 0 Hydrogenase-1 expression protein HyaE UL11 PF11094.3 KLO17216.1 - 0.28 11.0 0.9 24 4.8 0.0 3.0 3 0 0 3 3 3 0 Membrane-associated tegument protein WD40 PF00400.27 KLO17217.1 - 1.5e-49 164.2 13.1 3.5e-11 42.5 0.1 8.0 8 0 0 8 8 8 7 WD domain, G-beta repeat PQQ_2 PF13360.1 KLO17217.1 - 1.7e-05 24.4 4.6 0.002 17.6 3.0 3.3 1 1 1 2 2 2 2 PQQ-like domain DUF4613 PF15390.1 KLO17217.1 - 0.063 11.4 0.0 0.1 10.7 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4613) Acetyltransf_3 PF13302.1 KLO17218.1 - 1.1e-12 48.2 0.0 1.5e-12 47.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain RNase_HII PF01351.13 KLO17219.1 - 4e-48 163.7 0.0 5.5e-48 163.2 0.0 1.2 1 0 0 1 1 1 1 Ribonuclease HII MpPF26 PF07666.6 KLO17221.1 - 0.092 12.6 2.5 0.75 9.7 0.1 2.2 2 1 0 2 2 2 0 M penetrans paralogue family 26 SART-1 PF03343.8 KLO17222.1 - 7.9e-127 424.1 68.2 7.9e-127 424.1 47.3 1.8 2 0 0 2 2 2 1 SART-1 family DUF155 PF02582.9 KLO17223.1 - 6.5e-41 140.1 0.0 9.5e-41 139.6 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 TPR_16 PF13432.1 KLO17224.1 - 4e-14 52.8 0.0 1.9e-05 25.1 0.0 3.9 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.1 KLO17224.1 - 2e-11 44.0 5.2 9.4e-06 25.8 0.0 4.4 4 1 0 4 4 4 2 Tetratricopeptide repeat TPR_11 PF13414.1 KLO17224.1 - 3.5e-09 36.1 2.6 0.00037 20.0 0.0 4.3 4 1 0 4 4 4 2 TPR repeat TPR_17 PF13431.1 KLO17224.1 - 8.7e-08 31.7 0.0 0.0035 17.4 0.0 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.1 KLO17224.1 - 5.8e-07 29.5 1.3 0.69 10.7 0.0 5.3 3 2 3 6 6 6 2 Tetratricopeptide repeat Apc3 PF12895.2 KLO17224.1 - 1.9e-06 27.9 1.7 0.0014 18.6 0.0 3.5 3 1 1 4 4 4 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.1 KLO17224.1 - 1.9e-06 27.7 0.3 0.048 13.5 0.0 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_9 PF13371.1 KLO17224.1 - 3.3e-05 23.6 1.0 0.29 10.9 0.1 2.8 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.12 KLO17224.1 - 3.4e-05 23.4 4.2 2.7 8.1 0.0 5.5 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_1 PF00515.23 KLO17224.1 - 0.00012 21.4 4.0 7.5 6.3 0.0 5.0 5 0 0 5 5 5 1 Tetratricopeptide repeat Alkyl_sulf_dimr PF14863.1 KLO17224.1 - 0.017 15.3 0.2 7 6.8 0.0 2.3 2 0 0 2 2 2 0 Alkyl sulfatase dimerisation Fis1_TPR_C PF14853.1 KLO17224.1 - 0.026 14.3 0.2 1.6 8.6 0.0 3.4 3 1 1 4 4 3 0 Fis1 C-terminal tetratricopeptide repeat TPR_6 PF13174.1 KLO17224.1 - 0.027 14.9 3.3 2.9 8.5 0.0 4.3 5 0 0 5 5 5 0 Tetratricopeptide repeat Phage_capsid PF05065.8 KLO17224.1 - 0.075 12.2 0.1 0.13 11.3 0.1 1.3 1 0 0 1 1 1 0 Phage capsid family Coatomer_E PF04733.9 KLO17224.1 - 0.22 10.6 4.3 1.2 8.3 0.0 3.3 4 0 0 4 4 4 0 Coatomer epsilon subunit GTF2I PF02946.9 KLO17225.1 - 0.059 13.2 0.0 0.1 12.4 0.0 1.4 1 0 0 1 1 1 0 GTF2I-like repeat Svf1 PF08622.5 KLO17226.1 - 2.1e-84 283.3 0.0 2.4e-84 283.1 0.0 1.0 1 0 0 1 1 1 1 Svf1-like FmdA_AmdA PF03069.10 KLO17227.1 - 1.2e-143 478.3 0.0 1.3e-143 478.1 0.0 1.0 1 0 0 1 1 1 1 Acetamidase/Formamidase family Arrestin_N PF00339.24 KLO17228.1 - 1.8e-05 24.5 0.0 0.00025 20.8 0.0 2.5 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain LysE PF01810.13 KLO17230.1 - 0.033 13.4 1.6 0.034 13.4 0.2 1.7 2 0 0 2 2 2 0 LysE type translocator CreD PF06123.7 KLO17230.1 - 0.16 10.5 5.3 0.022 13.3 0.8 1.6 2 0 0 2 2 2 0 Inner membrane protein CreD Aconitase PF00330.15 KLO17231.1 - 2.7e-72 243.7 2.2 1.1e-40 139.5 0.1 3.1 2 1 1 3 3 3 3 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 KLO17231.1 - 7.7e-20 71.3 0.0 2e-19 69.9 0.0 1.7 1 1 0 1 1 1 1 Aconitase C-terminal domain DUF521 PF04412.8 KLO17231.1 - 0.058 11.9 0.0 0.093 11.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF521) TauD PF02668.11 KLO17232.1 - 2.1e-39 135.7 0.1 3.3e-39 135.1 0.1 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DUF971 PF06155.7 KLO17232.1 - 7.3e-07 29.5 0.0 1.6e-06 28.4 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF971) CsiD PF08943.5 KLO17232.1 - 0.00015 20.7 0.1 0.027 13.3 0.0 2.2 2 0 0 2 2 2 2 CsiD 2OG-FeII_Oxy_3 PF13640.1 KLO17232.1 - 0.011 16.2 0.3 0.052 14.0 0.0 2.1 2 0 0 2 2 2 0 2OG-Fe(II) oxygenase superfamily RabGAP-TBC PF00566.13 KLO17233.1 - 1.5e-50 171.6 0.0 8.9e-50 169.1 0.0 2.2 2 0 0 2 2 2 1 Rab-GTPase-TBC domain COX6B PF02297.12 KLO17234.1 - 4.8e-22 77.7 2.1 6.7e-22 77.2 1.4 1.2 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb Sugar_tr PF00083.19 KLO17236.1 - 3.8e-49 167.4 22.4 5.5e-49 166.9 15.5 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KLO17236.1 - 2.1e-20 72.7 23.5 2.1e-20 72.7 16.3 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily DPBB_1 PF03330.13 KLO17238.1 - 1.1e-06 28.5 0.0 1.2e-06 28.3 0.0 1.1 1 0 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel DUF1748 PF08520.5 KLO17240.1 - 1.5e-24 85.4 0.0 1.6e-24 85.2 0.0 1.0 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1748) Enolase_C PF00113.17 KLO17242.1 - 9.2e-144 477.8 0.1 1.3e-143 477.3 0.1 1.1 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.11 KLO17242.1 - 9.2e-58 193.8 0.3 1.6e-57 193.0 0.2 1.4 1 0 0 1 1 1 1 Enolase, N-terminal domain MR_MLE_C PF13378.1 KLO17242.1 - 7.5e-05 22.6 0.1 0.00027 20.8 0.0 2.0 2 0 0 2 2 2 1 Enolase C-terminal domain-like MAAL_C PF07476.6 KLO17242.1 - 0.0024 16.8 0.4 0.0045 15.9 0.2 1.5 1 0 0 1 1 1 1 Methylaspartate ammonia-lyase C-terminus MR_MLE PF01188.16 KLO17242.1 - 0.1 13.1 0.0 0.24 11.9 0.0 1.7 1 0 0 1 1 1 0 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain IlvN PF07991.7 KLO17243.1 - 9.5e-47 158.4 0.0 1.8e-46 157.5 0.0 1.4 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain IlvC PF01450.14 KLO17243.1 - 4e-42 143.5 0.0 5.9e-42 143.0 0.0 1.3 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain NAD_binding_2 PF03446.10 KLO17243.1 - 0.026 14.3 0.0 0.052 13.3 0.0 1.5 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Abhydrolase_6 PF12697.2 KLO17244.1 - 1.4e-25 90.5 0.2 2e-25 90.0 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KLO17244.1 - 2.2e-08 33.9 0.0 5e-08 32.8 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KLO17244.1 - 1.4e-05 24.8 0.0 0.00023 20.7 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.3 KLO17244.1 - 0.0089 15.8 0.0 0.018 14.8 0.0 1.4 1 0 0 1 1 1 1 Putative lysophospholipase Thioesterase PF00975.15 KLO17244.1 - 0.0094 16.1 0.0 0.042 14.0 0.0 2.0 2 1 0 2 2 2 1 Thioesterase domain PGAP1 PF07819.8 KLO17244.1 - 0.05 13.1 0.0 0.076 12.5 0.0 1.2 1 0 0 1 1 1 0 PGAP1-like protein AAA PF00004.24 KLO17245.1 - 3e-93 308.9 0.0 1.6e-46 157.7 0.0 2.6 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 KLO17245.1 - 3.8e-15 55.5 0.0 5.4e-08 32.1 0.0 2.4 2 0 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 KLO17245.1 - 4.3e-14 52.9 2.2 0.00021 21.3 0.0 4.9 3 2 1 4 4 4 2 AAA ATPase domain AAA_22 PF13401.1 KLO17245.1 - 5.2e-14 52.4 0.0 0.0012 18.9 0.0 5.6 3 2 1 4 4 4 2 AAA domain AAA_17 PF13207.1 KLO17245.1 - 2e-11 44.7 0.0 4.2e-06 27.5 0.0 2.8 2 1 0 2 2 2 2 AAA domain AAA_5 PF07728.9 KLO17245.1 - 1.1e-10 41.3 0.3 0.00044 19.9 0.0 3.9 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_14 PF13173.1 KLO17245.1 - 2.7e-10 40.2 0.0 0.00017 21.4 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_33 PF13671.1 KLO17245.1 - 1.7e-09 37.6 0.0 0.00031 20.6 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_2 PF07724.9 KLO17245.1 - 2.6e-09 37.2 0.0 0.00092 19.1 0.0 2.5 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) TIP49 PF06068.8 KLO17245.1 - 8.2e-09 34.6 0.0 0.00022 20.0 0.0 2.3 2 0 0 2 2 2 2 TIP49 C-terminus Zeta_toxin PF06414.7 KLO17245.1 - 1.1e-08 34.4 0.0 0.002 17.2 0.0 2.4 2 0 0 2 2 2 2 Zeta toxin AAA_19 PF13245.1 KLO17245.1 - 2.6e-08 33.4 1.0 0.0021 17.7 0.1 3.2 2 2 0 2 2 2 2 Part of AAA domain AAA_25 PF13481.1 KLO17245.1 - 1.1e-07 31.3 3.8 0.68 9.2 0.0 4.4 2 2 2 4 4 4 2 AAA domain RNA_helicase PF00910.17 KLO17245.1 - 2.6e-07 30.7 0.0 0.039 14.1 0.0 2.8 2 1 0 2 2 2 2 RNA helicase IstB_IS21 PF01695.12 KLO17245.1 - 3.1e-07 29.9 0.0 0.025 13.9 0.0 2.4 2 0 0 2 2 2 2 IstB-like ATP binding protein Mg_chelatase PF01078.16 KLO17245.1 - 5e-07 29.0 0.1 0.03 13.5 0.0 2.4 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI NACHT PF05729.7 KLO17245.1 - 5.5e-07 29.3 0.2 0.086 12.4 0.0 4.0 3 1 0 3 3 3 2 NACHT domain AAA_3 PF07726.6 KLO17245.1 - 3.3e-06 26.7 0.0 0.017 14.6 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.1 KLO17245.1 - 3.4e-06 27.1 0.0 0.077 12.9 0.0 2.5 2 0 0 2 2 2 2 AAA domain ABC_tran PF00005.22 KLO17245.1 - 5.9e-06 26.6 0.0 0.066 13.5 0.0 2.7 2 1 0 2 2 2 2 ABC transporter AAA_18 PF13238.1 KLO17245.1 - 6.1e-06 26.5 0.0 0.057 13.7 0.0 2.5 2 0 0 2 2 2 2 AAA domain Sigma54_activ_2 PF14532.1 KLO17245.1 - 1.6e-05 24.9 0.0 0.61 10.1 0.0 3.3 3 0 0 3 3 3 2 Sigma-54 interaction domain Sigma54_activat PF00158.21 KLO17245.1 - 1.7e-05 24.3 0.0 0.34 10.3 0.0 3.9 4 1 0 4 4 3 2 Sigma-54 interaction domain Arch_ATPase PF01637.13 KLO17245.1 - 6e-05 22.8 0.0 1.5 8.4 0.0 3.3 2 2 1 3 3 3 2 Archaeal ATPase KaiC PF06745.8 KLO17245.1 - 0.00014 21.0 0.1 2 7.4 0.0 3.2 2 1 1 3 3 3 2 KaiC NB-ARC PF00931.17 KLO17245.1 - 0.00019 20.3 0.0 0.34 9.7 0.0 2.3 2 0 0 2 2 2 2 NB-ARC domain Cytidylate_kin2 PF13189.1 KLO17245.1 - 0.0003 20.7 0.0 0.031 14.1 0.0 2.2 2 0 0 2 2 2 1 Cytidylate kinase-like family Viral_helicase1 PF01443.13 KLO17245.1 - 0.00036 20.1 0.0 0.93 8.9 0.0 2.3 2 0 0 2 2 2 2 Viral (Superfamily 1) RNA helicase PhoH PF02562.11 KLO17245.1 - 0.001 18.3 0.1 1.5 7.9 0.0 2.3 2 0 0 2 2 2 2 PhoH-like protein Parvo_NS1 PF01057.12 KLO17245.1 - 0.0011 17.8 0.0 1.2 7.9 0.0 2.2 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 DUF815 PF05673.8 KLO17245.1 - 0.0011 17.9 0.0 0.053 12.4 0.0 2.8 3 0 0 3 3 3 1 Protein of unknown function (DUF815) SKI PF01202.17 KLO17245.1 - 0.0012 18.7 0.0 1.3 8.8 0.0 2.4 2 0 0 2 2 2 1 Shikimate kinase ATP-synt_ab PF00006.20 KLO17245.1 - 0.0049 16.3 0.0 2.9 7.3 0.0 2.5 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain Bac_DnaA PF00308.13 KLO17245.1 - 0.0051 16.4 0.0 3.6 7.1 0.0 2.6 2 1 0 2 2 2 0 Bacterial dnaA protein UPF0079 PF02367.12 KLO17245.1 - 0.0059 16.2 0.0 2 8.0 0.0 2.5 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 CPT PF07931.7 KLO17245.1 - 0.0068 16.0 0.0 0.53 9.8 0.0 2.3 2 0 0 2 2 2 1 Chloramphenicol phosphotransferase-like protein AFG1_ATPase PF03969.11 KLO17245.1 - 0.0075 15.1 0.0 4.1 6.1 0.0 2.7 3 0 0 3 3 2 0 AFG1-like ATPase NTPase_1 PF03266.10 KLO17245.1 - 0.0098 15.6 0.1 3.2 7.4 0.0 3.0 3 0 0 3 3 3 0 NTPase AAA_11 PF13086.1 KLO17245.1 - 0.0099 15.4 0.0 2.9 7.4 0.0 2.3 2 0 0 2 2 2 1 AAA domain DUF2075 PF09848.4 KLO17245.1 - 0.011 14.7 0.0 0.74 8.7 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA_24 PF13479.1 KLO17245.1 - 0.02 14.5 0.0 3.3 7.2 0.0 2.3 2 0 0 2 2 2 0 AAA domain Rad17 PF03215.10 KLO17245.1 - 0.021 13.5 0.0 3.9 6.0 0.0 2.2 2 0 0 2 2 2 0 Rad17 cell cycle checkpoint protein SRPRB PF09439.5 KLO17245.1 - 0.038 13.1 0.0 6.9 5.8 0.0 2.4 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit PduV-EutP PF10662.4 KLO17245.1 - 0.057 12.9 0.0 10 5.5 0.0 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation MMR_HSR1 PF01926.18 KLO17245.1 - 0.067 13.1 0.0 3.7 7.5 0.0 2.7 2 1 0 2 2 2 0 50S ribosome-binding GTPase AAA_10 PF12846.2 KLO17245.1 - 0.072 12.5 0.1 19 4.5 0.0 3.2 3 1 0 3 3 3 0 AAA-like domain ResIII PF04851.10 KLO17245.1 - 0.073 12.8 0.0 15 5.3 0.0 2.5 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit FeoB_N PF02421.13 KLO17245.1 - 0.24 10.6 0.1 6.9 5.9 0.0 2.3 2 0 0 2 2 2 0 Ferrous iron transport protein B Serinc PF03348.10 KLO17246.1 - 1.2e-153 511.8 5.8 1.5e-153 511.5 4.0 1.0 1 0 0 1 1 1 1 Serine incorporator (Serinc) FA_desaturase PF00487.19 KLO17246.1 - 0.58 9.5 13.6 0.25 10.7 4.0 3.1 2 1 1 3 3 3 0 Fatty acid desaturase DUF267 PF03268.9 KLO17246.1 - 2 7.2 11.8 2.9 6.6 3.0 2.5 2 0 0 2 2 2 0 Caenorhabditis protein of unknown function, DUF267 Rad51 PF08423.6 KLO17247.1 - 7.2e-14 51.3 0.0 1e-13 50.7 0.0 1.1 1 0 0 1 1 1 1 Rad51 AAA_25 PF13481.1 KLO17247.1 - 2.6e-05 23.7 0.2 4.6e-05 22.9 0.1 1.3 1 0 0 1 1 1 1 AAA domain SPR1 PF15356.1 KLO17250.1 - 0.078 13.3 1.8 0.095 13.0 1.3 1.2 1 0 0 1 1 1 0 Psoriasis susceptibility locus 2 Gti1_Pac2 PF09729.4 KLO17252.1 - 5.6e-49 166.2 0.0 7.4e-49 165.8 0.0 1.2 1 0 0 1 1 1 1 Gti1/Pac2 family Tfb2 PF03849.9 KLO17254.1 - 3.5e-120 400.9 0.2 6.3e-120 400.1 0.0 1.4 2 0 0 2 2 2 1 Transcription factor Tfb2 Helicase_C_3 PF13625.1 KLO17254.1 - 2.4e-05 24.0 0.0 6.6e-05 22.6 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Ank_5 PF13857.1 KLO17255.1 - 5.1e-16 58.3 1.1 7.8e-12 45.0 0.3 2.0 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.2 KLO17255.1 - 2.4e-15 56.6 0.4 4.1e-15 55.8 0.3 1.3 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 KLO17255.1 - 9.1e-15 53.6 2.6 4.1e-11 42.1 0.1 3.1 3 0 0 3 3 3 3 Ankyrin repeat Ank_3 PF13606.1 KLO17255.1 - 2.4e-13 48.8 1.2 2.1e-07 30.5 0.0 3.0 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.1 KLO17255.1 - 3.3e-12 46.5 0.9 1.2e-07 32.0 0.1 2.2 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.1 KLO17256.1 - 2.5e-19 68.8 0.0 3.8e-09 36.5 0.0 2.2 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.2 KLO17256.1 - 1.8e-16 60.2 0.0 6.4e-07 29.6 0.0 2.0 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 KLO17256.1 - 1.1e-15 56.5 1.4 2.6e-06 26.9 0.0 3.4 4 0 0 4 4 4 3 Ankyrin repeat Ank_4 PF13637.1 KLO17256.1 - 5.2e-11 42.7 0.2 2.4e-05 24.7 0.0 2.7 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 KLO17256.1 - 1.1e-10 40.6 0.0 4.3e-05 23.3 0.0 3.1 3 0 0 3 3 3 2 Ankyrin repeat She9_MDM33 PF05546.6 KLO17257.1 - 1.3e-68 230.6 7.1 1.8e-68 230.1 4.9 1.2 1 0 0 1 1 1 1 She9 / Mdm33 family DUF1110 PF06533.7 KLO17257.1 - 2.8e-06 27.2 2.8 0.0065 16.3 0.1 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF1110) SPARC_Ca_bdg PF10591.4 KLO17257.1 - 0.11 12.5 1.2 9.8 6.2 0.0 2.6 1 1 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region V_ATPase_I PF01496.14 KLO17257.1 - 2.3 5.9 5.9 2.9 5.6 4.1 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Siah-Interact_N PF09032.6 KLO17257.1 - 6.4 6.9 16.6 4.7 7.3 3.6 3.5 3 1 1 4 4 4 0 Siah interacting protein, N terminal FAD_binding_1 PF00667.15 KLO17258.1 - 2.9e-53 180.5 0.0 1.9e-52 177.8 0.0 2.0 1 1 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.20 KLO17258.1 - 9e-32 110.0 0.5 1.5e-31 109.3 0.4 1.4 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.16 KLO17258.1 - 2.7e-23 82.5 0.0 1.8e-22 79.9 0.0 2.2 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain Flavodoxin_5 PF12724.2 KLO17258.1 - 0.089 12.7 0.0 0.18 11.7 0.0 1.5 1 0 0 1 1 1 0 Flavodoxin domain DDE_Tnp_1_4 PF13701.1 KLO17258.1 - 0.27 9.3 0.0 0.39 8.8 0.0 1.1 1 0 0 1 1 1 0 Transposase DDE domain group 1 DASH_Dad1 PF08649.5 KLO17259.1 - 9.8e-14 50.8 0.1 1.3e-13 50.3 0.1 1.1 1 0 0 1 1 1 1 DASH complex subunit Dad1 DUF515 PF04415.7 KLO17259.1 - 0.027 12.7 0.0 0.031 12.5 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF515) Pkinase PF00069.20 KLO17260.1 - 1.9e-65 220.6 0.0 3.9e-65 219.5 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KLO17260.1 - 8.1e-35 120.1 0.0 1.6e-34 119.1 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase HR1 PF02185.11 KLO17260.1 - 6.2e-22 77.1 14.8 2.4e-14 52.8 2.5 2.6 2 0 0 2 2 2 2 Hr1 repeat C1_1 PF00130.17 KLO17260.1 - 3.7e-20 71.3 28.6 5e-11 42.1 7.0 2.5 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) Pkinase_C PF00433.19 KLO17260.1 - 6.4e-10 39.3 0.4 6.4e-10 39.3 0.3 2.3 2 0 0 2 2 2 1 Protein kinase C terminal domain C2 PF00168.25 KLO17260.1 - 0.00012 21.8 0.1 0.00025 20.8 0.0 1.5 1 0 0 1 1 1 1 C2 domain Peptidase_M6 PF05547.6 KLO17260.1 - 0.023 12.7 0.0 0.037 12.0 0.0 1.2 1 0 0 1 1 1 0 Immune inhibitor A peptidase M6 Uds1 PF15456.1 KLO17260.1 - 0.88 9.5 10.8 0.14 12.1 1.0 2.7 2 0 0 2 2 2 0 Up-regulated During Septation Endosulfine PF04667.12 KLO17262.1 - 1.5e-19 69.7 0.1 2.2e-19 69.2 0.0 1.3 1 0 0 1 1 1 1 cAMP-regulated phosphoprotein/endosulfine conserved region DEAD PF00270.24 KLO17264.1 - 6.8e-06 25.6 0.2 7.7e-06 25.4 0.2 1.1 1 0 0 1 1 1 1 DEAD/DEAH box helicase UvrD-helicase PF00580.16 KLO17264.1 - 0.013 14.8 0.0 0.015 14.6 0.0 1.2 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain Tir_receptor_C PF07489.6 KLO17264.1 - 0.023 14.4 0.1 0.024 14.3 0.1 1.1 1 0 0 1 1 1 0 Translocated intimin receptor (Tir) C-terminus Kinesin PF00225.18 KLO17264.1 - 0.027 13.1 0.0 0.03 13.0 0.0 1.0 1 0 0 1 1 1 0 Kinesin motor domain DNA_pol_E_B PF04042.11 KLO17265.1 - 6.3e-28 97.4 1.6 9.2e-28 96.9 1.1 1.2 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B Pol_alpha_B_N PF08418.5 KLO17265.1 - 5.8e-11 42.4 0.2 1.1e-06 28.3 0.0 2.3 1 1 0 2 2 2 2 DNA polymerase alpha subunit B N-terminal RasGEF PF00617.14 KLO17266.1 - 1.1e-59 201.3 0.1 2e-59 200.4 0.1 1.5 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.15 KLO17266.1 - 9.9e-22 77.0 0.1 3.6e-21 75.2 0.1 2.1 1 0 0 1 1 1 1 RasGEF N-terminal motif SH3_1 PF00018.23 KLO17266.1 - 2.7e-14 52.2 0.1 6.5e-14 51.0 0.1 1.7 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 KLO17266.1 - 4.7e-12 45.2 0.0 9.6e-12 44.2 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.1 KLO17266.1 - 4.9e-12 45.2 0.2 1.2e-11 44.0 0.1 1.7 1 0 0 1 1 1 1 Variant SH3 domain WW PF00397.21 KLO17266.1 - 7.9e-07 28.8 2.1 0.0014 18.4 0.3 2.6 2 0 0 2 2 2 2 WW domain GTP_EFTU PF00009.22 KLO17267.1 - 6.6e-50 169.1 0.0 1.2e-49 168.3 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_C PF00679.19 KLO17267.1 - 2.9e-15 55.9 0.0 7.3e-15 54.6 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 KLO17267.1 - 3.6e-08 33.4 0.0 9.5e-08 32.0 0.0 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_II PF14492.1 KLO17267.1 - 1.8e-06 27.6 0.0 4.4e-06 26.4 0.0 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_IV PF03764.13 KLO17267.1 - 3.7e-06 26.4 0.0 0.00021 20.8 0.0 3.1 1 1 0 2 2 2 1 Elongation factor G, domain IV MMR_HSR1 PF01926.18 KLO17267.1 - 0.00013 21.8 0.0 0.00027 20.8 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 KLO17267.1 - 0.0015 18.9 0.0 0.0041 17.5 0.0 1.8 1 0 0 1 1 1 1 Miro-like protein G-alpha PF00503.15 KLO17267.1 - 0.19 10.4 0.0 0.39 9.3 0.0 1.4 1 0 0 1 1 1 0 G-protein alpha subunit cobW PF02492.14 KLO17268.1 - 7.8e-42 142.7 0.2 1e-41 142.3 0.1 1.2 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.9 KLO17268.1 - 6.3e-07 29.0 0.0 1.3e-06 27.9 0.0 1.5 1 0 0 1 1 1 1 Cobalamin synthesis protein cobW C-terminal domain GTP_EFTU PF00009.22 KLO17268.1 - 6.6e-05 22.4 0.2 0.023 14.1 0.0 2.2 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain ArgK PF03308.11 KLO17268.1 - 0.00089 18.1 0.5 0.22 10.2 0.0 3.0 3 0 0 3 3 3 1 ArgK protein AAA_10 PF12846.2 KLO17268.1 - 0.0047 16.4 0.0 0.0078 15.6 0.0 1.3 1 0 0 1 1 1 1 AAA-like domain Arch_ATPase PF01637.13 KLO17268.1 - 0.014 15.1 0.0 0.02 14.6 0.0 1.2 1 0 0 1 1 1 0 Archaeal ATPase AAA_29 PF13555.1 KLO17268.1 - 0.019 14.5 0.0 0.038 13.5 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_22 PF13401.1 KLO17268.1 - 0.023 14.8 0.0 0.042 13.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain Viral_helicase1 PF01443.13 KLO17268.1 - 0.026 14.0 0.0 0.039 13.4 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase Arf PF00025.16 KLO17268.1 - 0.035 13.3 0.1 3.6 6.8 0.0 2.2 2 0 0 2 2 2 0 ADP-ribosylation factor family MobB PF03205.9 KLO17268.1 - 0.039 13.6 0.3 0.35 10.5 0.0 2.4 2 1 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_33 PF13671.1 KLO17268.1 - 0.062 13.1 0.0 0.12 12.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.1 KLO17268.1 - 0.084 12.8 0.0 0.15 12.0 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain ABC_tran PF00005.22 KLO17268.1 - 0.099 12.9 0.1 0.32 11.2 0.0 1.8 2 0 0 2 2 2 0 ABC transporter AAA_18 PF13238.1 KLO17268.1 - 0.1 12.9 0.1 0.19 12.0 0.0 1.6 1 1 0 1 1 1 0 AAA domain Zeta_toxin PF06414.7 KLO17268.1 - 0.15 11.1 0.0 0.24 10.4 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin DSPc PF00782.15 KLO17269.1 - 1.5e-27 95.7 0.0 1.9e-27 95.4 0.0 1.1 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Init_tRNA_PT PF04179.7 KLO17269.1 - 0.0043 15.9 0.0 0.0044 15.9 0.0 1.1 1 0 0 1 1 1 1 Initiator tRNA phosphoribosyl transferase Y_phosphatase3 PF13350.1 KLO17269.1 - 0.033 14.4 0.1 0.6 10.3 0.0 2.1 1 1 1 2 2 2 0 Tyrosine phosphatase family UAA PF08449.6 KLO17270.1 - 1.6e-65 221.0 8.2 1e-60 205.2 4.1 2.0 2 0 0 2 2 2 2 UAA transporter family EamA PF00892.15 KLO17270.1 - 5.2e-09 36.2 17.6 1.4e-07 31.6 3.1 3.8 4 0 0 4 4 4 2 EamA-like transporter family EmrE PF13536.1 KLO17270.1 - 1.3e-06 28.5 21.8 3.4e-05 24.0 1.5 4.4 4 1 0 5 5 5 2 Multidrug resistance efflux transporter TPT PF03151.11 KLO17270.1 - 0.00012 21.7 11.2 0.00041 20.0 2.8 2.8 3 0 0 3 3 3 2 Triose-phosphate Transporter family Nuc_sug_transp PF04142.10 KLO17270.1 - 0.00058 19.0 3.8 0.17 10.9 0.5 2.6 2 1 0 2 2 2 2 Nucleotide-sugar transporter UPF0546 PF10639.4 KLO17270.1 - 0.014 15.2 2.2 0.65 9.8 0.1 2.8 2 0 0 2 2 2 0 Uncharacterised protein family UPF0546 DUF427 PF04248.7 KLO17271.1 - 8.4e-30 102.3 2.1 9.1e-30 102.1 1.4 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF427) IBR PF01485.16 KLO17272.1 - 8.3e-07 28.7 6.1 8.3e-07 28.7 4.2 4.0 3 1 0 3 3 3 2 IBR domain zf-RING_2 PF13639.1 KLO17272.1 - 2.7e-06 27.0 8.6 2.7e-06 27.0 6.0 3.9 3 1 0 3 3 3 2 Ring finger domain zf-C3HC4 PF00097.20 KLO17272.1 - 4.5e-05 23.0 7.8 4.5e-05 23.0 5.4 4.7 3 2 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KLO17272.1 - 0.0012 18.8 9.0 0.0012 18.8 6.2 4.6 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KLO17272.1 - 0.0018 17.9 8.2 0.0018 17.9 5.7 4.2 3 1 1 4 4 4 1 zinc-RING finger domain HALZ PF02183.13 KLO17272.1 - 0.013 15.1 1.5 0.06 13.0 0.4 2.3 2 0 0 2 2 2 0 Homeobox associated leucine zipper zf-RING_3 PF14369.1 KLO17272.1 - 0.093 12.7 21.9 0.34 10.9 2.1 4.9 4 1 0 4 4 4 0 zinc-finger Mito_carr PF00153.22 KLO17273.1 - 2.3e-75 248.3 0.0 3.8e-26 90.6 0.0 3.3 3 1 0 3 3 3 3 Mitochondrial carrier protein DUF4448 PF14610.1 KLO17274.1 - 8.2e-05 22.1 0.0 0.00037 20.0 0.0 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF4448) DUF1517 PF07466.6 KLO17274.1 - 0.0046 15.9 2.0 0.0098 14.9 1.4 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1517) TrbL PF04610.9 KLO17274.1 - 0.58 9.8 6.6 0.91 9.1 4.6 1.2 1 0 0 1 1 1 0 TrbL/VirB6 plasmid conjugal transfer protein UBN2_2 PF14227.1 KLO17275.1 - 0.0072 15.8 0.0 0.011 15.3 0.0 1.2 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type CwfJ_C_1 PF04677.10 KLO17276.1 - 6.7e-31 106.4 0.2 9.8e-31 105.9 0.2 1.2 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 CwfJ_C_2 PF04676.9 KLO17276.1 - 6.8e-24 84.2 0.0 1.9e-23 82.8 0.0 1.8 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 2 HpcH_HpaI PF03328.9 KLO17277.1 - 1.1e-41 142.2 0.0 1.4e-41 141.8 0.0 1.2 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family C-C_Bond_Lyase PF15617.1 KLO17277.1 - 5e-12 45.2 0.2 2.9e-06 26.3 0.0 2.2 1 1 0 2 2 2 2 C-C_Bond_Lyase of the TIM-Barrel fold Rsa3 PF14615.1 KLO17278.1 - 1.7e-13 49.5 0.1 2.4e-13 49.1 0.1 1.2 1 0 0 1 1 1 1 Ribosome-assembly protein 3 DUF755 PF05501.6 KLO17278.1 - 1.6 8.7 33.0 2.5 8.2 8.9 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF755) Macoilin PF09726.4 KLO17278.1 - 2.9 6.0 20.4 5.3 5.2 14.1 1.3 1 1 0 1 1 1 0 Transmembrane protein DUF1675 PF07897.6 KLO17278.1 - 3.2 7.5 10.7 5 6.9 7.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) Helicase_C PF00271.26 KLO17279.1 - 2.9e-12 46.2 0.0 4.4e-12 45.6 0.0 1.3 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Peptidase_C97 PF05903.9 KLO17281.1 - 7.4e-41 139.4 0.0 1.3e-40 138.6 0.0 1.4 1 0 0 1 1 1 1 PPPDE putative peptidase domain PUL PF08324.6 KLO17281.1 - 2.1e-24 85.7 0.3 3.5e-24 85.0 0.2 1.3 1 0 0 1 1 1 1 PUL domain Thioredoxin PF00085.15 KLO17281.1 - 3.8e-15 55.4 0.0 8.2e-15 54.3 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.1 KLO17281.1 - 5.4e-05 23.3 0.2 0.00052 20.1 0.2 2.2 1 1 0 1 1 1 1 Thioredoxin-like domain Redoxin PF08534.5 KLO17281.1 - 0.0047 16.4 0.1 0.052 13.0 0.1 2.1 2 0 0 2 2 2 1 Redoxin AhpC-TSA PF00578.16 KLO17281.1 - 0.059 13.0 0.0 0.12 12.0 0.0 1.5 1 0 0 1 1 1 0 AhpC/TSA family DSBA PF01323.15 KLO17281.1 - 0.12 11.9 0.0 0.29 10.6 0.0 1.6 1 1 0 1 1 1 0 DSBA-like thioredoxin domain Ribosom_S12_S23 PF00164.20 KLO17282.1 - 4.8e-48 161.6 3.1 5.3e-48 161.4 2.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S12/S23 DUF3186 PF11382.3 KLO17282.1 - 0.047 12.8 0.0 0.05 12.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3186) PH_4 PF15404.1 KLO17283.1 - 2.8e-27 95.4 3.0 3.2e-24 85.4 1.3 3.0 2 1 0 2 2 2 1 Pleckstrin homology domain AOX PF01786.12 KLO17284.1 - 1.1e-85 286.2 0.1 1.7e-85 285.6 0.0 1.3 1 0 0 1 1 1 1 Alternative oxidase Zn_clus PF00172.13 KLO17285.1 - 0.00024 20.9 12.1 0.00059 19.6 8.4 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Carn_acyltransf PF00755.15 KLO17286.1 - 3.1e-163 544.0 0.0 3.6e-163 543.8 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase Methyltransf_31 PF13847.1 KLO17290.1 - 3.4e-18 65.6 0.0 6.8e-18 64.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KLO17290.1 - 8.3e-17 61.4 0.0 2.7e-15 56.5 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KLO17290.1 - 8.9e-15 55.2 0.0 1.7e-14 54.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KLO17290.1 - 1.2e-13 51.0 0.0 2.1e-13 50.2 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 KLO17290.1 - 2.6e-11 43.4 0.0 4.2e-11 42.7 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_12 PF08242.7 KLO17290.1 - 6.3e-11 42.6 0.0 1e-10 41.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KLO17290.1 - 2.2e-10 40.0 0.0 1.7e-09 37.1 0.0 2.2 1 1 0 2 2 2 1 ubiE/COQ5 methyltransferase family MTS PF05175.9 KLO17290.1 - 2.6e-09 36.6 0.0 7.5e-09 35.1 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.1 KLO17290.1 - 9.8e-09 35.4 0.0 2.1e-08 34.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KLO17290.1 - 3.9e-06 26.8 0.0 2.4e-05 24.3 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_32 PF13679.1 KLO17290.1 - 6.9e-06 25.7 0.0 1.5e-05 24.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_9 PF08003.6 KLO17290.1 - 1e-05 24.4 0.0 1.5e-05 23.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) GCD14 PF08704.5 KLO17290.1 - 1.1e-05 25.0 0.0 1.9e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit PrmA PF06325.8 KLO17290.1 - 1.2e-05 24.6 0.0 1.9e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) N6_Mtase PF02384.11 KLO17290.1 - 0.00027 20.1 0.0 0.00038 19.6 0.0 1.2 1 0 0 1 1 1 1 N-6 DNA Methylase RrnaAD PF00398.15 KLO17290.1 - 0.00064 18.8 0.0 0.001 18.1 0.0 1.3 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase ADH_zinc_N PF00107.21 KLO17290.1 - 0.0022 17.5 0.0 0.014 14.9 0.0 2.1 1 1 0 1 1 1 1 Zinc-binding dehydrogenase DOT1 PF08123.8 KLO17290.1 - 0.0035 16.6 0.0 0.0062 15.8 0.0 1.4 1 0 0 1 1 1 1 Histone methylation protein DOT1 CMAS PF02353.15 KLO17290.1 - 0.012 14.7 0.0 0.02 14.0 0.0 1.4 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase MetW PF07021.7 KLO17290.1 - 0.015 14.6 0.0 0.023 14.0 0.0 1.3 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Methyltransf_4 PF02390.12 KLO17290.1 - 0.027 13.5 0.0 0.056 12.4 0.0 1.5 1 0 0 1 1 1 0 Putative methyltransferase UPF0020 PF01170.13 KLO17290.1 - 0.036 13.6 0.0 0.066 12.7 0.0 1.4 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 DREV PF05219.7 KLO17290.1 - 0.037 12.8 0.0 0.1 11.4 0.0 1.7 2 0 0 2 2 2 0 DREV methyltransferase AP_endonuc_2 PF01261.19 KLO17290.1 - 0.047 12.9 0.0 0.13 11.5 0.0 1.7 2 0 0 2 2 2 0 Xylose isomerase-like TIM barrel FliG_C PF01706.11 KLO17290.1 - 0.069 13.1 0.0 0.12 12.3 0.0 1.3 1 0 0 1 1 1 0 FliG C-terminal domain Methyltransf_7 PF03492.10 KLO17290.1 - 0.084 11.6 0.0 12 4.5 0.0 2.8 3 0 0 3 3 3 0 SAM dependent carboxyl methyltransferase FtsJ PF01728.14 KLO17290.1 - 0.086 12.8 0.1 0.3 11.0 0.0 1.8 1 1 0 1 1 1 0 FtsJ-like methyltransferase Pkinase PF00069.20 KLO17291.1 - 2.9e-13 49.5 0.0 7.1e-11 41.7 0.0 2.1 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 KLO17291.1 - 0.0027 16.8 0.0 0.0058 15.7 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 KLO17291.1 - 0.055 12.5 0.0 0.09 11.8 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.20 KLO17292.1 - 3.7e-30 104.9 0.0 5.3e-30 104.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KLO17292.1 - 8.3e-23 80.7 0.0 1.6e-22 79.8 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Dus PF01207.12 KLO17293.1 - 6.7e-54 182.8 0.0 1.1e-53 182.1 0.0 1.3 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) zf-CCCH PF00642.19 KLO17293.1 - 1.1 8.9 7.5 0.52 10.0 1.4 2.4 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Peptidase_M20 PF01546.23 KLO17294.1 - 5.4e-23 81.4 0.0 8.5e-23 80.8 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 WD40 PF00400.27 KLO17294.1 - 7.8e-16 57.2 17.3 5.7e-07 29.1 0.2 7.0 7 0 0 7 7 7 4 WD domain, G-beta repeat M20_dimer PF07687.9 KLO17294.1 - 2.4e-10 40.1 0.0 4.2e-10 39.3 0.0 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain HA2 PF04408.18 KLO17295.1 - 2.5e-22 78.7 0.0 5.6e-22 77.6 0.0 1.6 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.26 KLO17295.1 - 3.4e-16 58.8 0.0 7.4e-16 57.7 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain OB_NTP_bind PF07717.11 KLO17295.1 - 3.2e-10 39.8 0.0 7.9e-10 38.5 0.0 1.7 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold DEAD PF00270.24 KLO17295.1 - 4.7e-06 26.1 0.0 2e-05 24.1 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_22 PF13401.1 KLO17295.1 - 0.0006 19.9 0.0 0.0015 18.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.22 KLO17295.1 - 0.00078 19.7 0.6 0.7 10.1 0.0 3.2 3 0 0 3 3 3 1 ABC transporter T2SE PF00437.15 KLO17295.1 - 0.029 13.2 0.0 0.058 12.2 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein G-alpha PF00503.15 KLO17295.1 - 0.047 12.3 0.2 0.079 11.6 0.1 1.3 1 0 0 1 1 1 0 G-protein alpha subunit AAA_19 PF13245.1 KLO17295.1 - 0.075 12.7 1.4 0.17 11.6 0.4 2.0 2 0 0 2 2 1 0 Part of AAA domain AAA_29 PF13555.1 KLO17295.1 - 0.077 12.5 0.1 0.6 9.6 0.0 2.3 2 0 0 2 2 2 0 P-loop containing region of AAA domain ResIII PF04851.10 KLO17295.1 - 0.13 12.1 0.0 21 4.8 0.0 2.4 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit KaiC PF06745.8 KLO17295.1 - 0.13 11.3 0.0 0.26 10.3 0.0 1.4 1 0 0 1 1 1 0 KaiC TPR_11 PF13414.1 KLO17296.1 - 7e-21 73.6 3.3 1.1e-15 57.0 0.2 2.2 1 1 1 2 2 2 2 TPR repeat RPAP3_C PF13877.1 KLO17296.1 - 5e-18 64.8 0.0 8.4e-18 64.1 0.0 1.4 1 0 0 1 1 1 1 Potential Monad-binding region of RPAP3 TPR_1 PF00515.23 KLO17296.1 - 5.8e-15 54.1 4.2 3.8e-05 23.1 0.2 3.2 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.12 KLO17296.1 - 5.8e-14 50.8 3.3 2.6e-05 23.8 0.3 3.3 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_16 PF13432.1 KLO17296.1 - 2.6e-07 31.1 2.4 0.00021 21.8 1.4 2.9 3 1 0 3 3 2 1 Tetratricopeptide repeat TPR_19 PF14559.1 KLO17296.1 - 2.7e-06 27.6 1.9 0.017 15.4 0.1 2.3 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.1 KLO17296.1 - 1.3e-05 25.4 2.5 0.091 13.4 0.6 3.6 2 1 2 4 4 3 2 Tetratricopeptide repeat TPR_9 PF13371.1 KLO17296.1 - 0.00012 21.8 1.3 0.00021 21.0 0.2 1.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.1 KLO17296.1 - 0.0069 16.2 3.0 0.027 14.3 0.8 2.2 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_6 PF13174.1 KLO17296.1 - 0.032 14.6 4.7 0.27 11.8 0.2 3.5 4 0 0 4 4 3 0 Tetratricopeptide repeat TPR_8 PF13181.1 KLO17296.1 - 0.056 13.2 3.2 0.51 10.2 0.1 2.6 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.1 KLO17296.1 - 0.091 12.5 0.4 9.5 6.3 0.1 2.7 2 1 0 2 2 2 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 KLO17296.1 - 0.13 12.1 3.2 1.9 8.4 0.1 2.7 2 1 1 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat TPR_17 PF13431.1 KLO17296.1 - 0.13 12.5 0.4 12 6.4 0.0 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat Glyco_hydro_52 PF03512.8 KLO17297.1 - 0.11 11.0 0.1 0.13 10.7 0.0 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 52 HrpF PF06266.7 KLO17297.1 - 0.12 12.5 0.1 0.19 11.8 0.1 1.3 1 0 0 1 1 1 0 HrpF protein PPR_2 PF13041.1 KLO17298.1 - 0.062 13.2 0.7 0.13 12.2 0.0 1.9 2 0 0 2 2 2 0 PPR repeat family MbtH PF03621.8 KLO17301.1 - 0.058 12.7 0.1 0.67 9.3 0.0 2.2 2 0 0 2 2 2 0 MbtH-like protein DUF4203 PF13886.1 KLO17304.1 - 6.3e-05 22.5 10.0 0.00011 21.7 6.9 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4203) TFIIF_alpha PF05793.7 KLO17304.1 - 0.0046 15.3 2.2 0.0065 14.9 1.5 1.1 1 0 0 1 1 1 1 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) zf-Nse PF11789.3 KLO17306.1 - 3e-15 55.4 0.0 4.9e-15 54.7 0.0 1.3 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-MIZ PF02891.15 KLO17306.1 - 0.0035 16.8 0.0 0.0061 16.0 0.0 1.4 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger zf-RING_UBOX PF13445.1 KLO17306.1 - 0.022 14.4 0.1 0.049 13.3 0.1 1.6 1 0 0 1 1 1 0 RING-type zinc-finger zf-RING_2 PF13639.1 KLO17306.1 - 0.07 12.9 0.0 0.12 12.2 0.0 1.3 1 0 0 1 1 1 0 Ring finger domain GFA PF04828.9 KLO17307.1 - 1.5e-06 28.0 0.3 1.5e-06 28.0 0.2 1.5 2 0 0 2 2 2 1 Glutathione-dependent formaldehyde-activating enzyme p450 PF00067.17 KLO17308.1 - 1.1e-54 185.7 0.0 3.5e-54 184.0 0.0 1.7 1 1 0 1 1 1 1 Cytochrome P450 ATP_bind_1 PF03029.12 KLO17310.1 - 0.049 13.1 0.1 0.056 12.9 0.0 1.1 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein Homeobox_KN PF05920.6 KLO17311.1 - 6.3e-16 57.7 0.0 8.6e-16 57.3 0.0 1.2 1 0 0 1 1 1 1 Homeobox KN domain Homeobox PF00046.24 KLO17311.1 - 1.8e-05 24.2 0.0 1.8e-05 24.2 0.0 1.2 1 0 0 1 1 1 1 Homeobox domain Homez PF11569.3 KLO17311.1 - 0.0038 16.2 0.3 0.0052 15.8 0.2 1.4 1 1 0 1 1 1 1 Homeodomain leucine-zipper encoding, Homez MGDG_synth PF06925.6 KLO17311.1 - 0.028 14.3 0.0 0.028 14.3 0.0 1.0 1 0 0 1 1 1 0 Monogalactosyldiacylglycerol (MGDG) synthase HTH_26 PF13443.1 KLO17311.1 - 0.15 12.2 0.0 0.24 11.6 0.0 1.3 1 0 0 1 1 1 0 Cro/C1-type HTH DNA-binding domain Rubella_Capsid PF05750.6 KLO17312.1 - 0.63 9.3 13.5 0.73 9.1 9.4 1.1 1 0 0 1 1 1 0 Rubella capsid protein Calc_CGRP_IAPP PF00214.14 KLO17312.1 - 0.82 9.7 3.1 0.97 9.4 2.2 1.1 1 0 0 1 1 1 0 Calcitonin / CGRP / IAPP family Lactamase_B_2 PF12706.2 KLO17313.1 - 0.023 14.2 1.0 0.024 14.1 0.7 1.1 1 0 0 1 1 1 0 Beta-lactamase superfamily domain Phage_hub_GP28 PF11110.3 KLO17313.1 - 0.029 14.0 0.0 0.036 13.7 0.0 1.0 1 0 0 1 1 1 0 Baseplate hub distal subunit LRR_8 PF13855.1 KLO17318.1 - 8.8e-27 92.6 33.8 2.2e-07 30.5 0.4 5.7 5 0 0 5 5 5 5 Leucine rich repeat LRR_4 PF12799.2 KLO17318.1 - 1.4e-26 91.6 42.9 2.4e-06 27.0 0.2 8.2 7 1 1 8 8 8 6 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 KLO17318.1 - 2.3e-05 23.8 44.3 1.4 9.2 0.1 11.6 11 1 1 12 12 12 4 Leucine Rich Repeat LRR_9 PF14580.1 KLO17318.1 - 0.00012 21.6 6.4 0.075 12.5 0.2 3.9 4 1 1 5 5 5 2 Leucine-rich repeat LRR_7 PF13504.1 KLO17318.1 - 0.00018 21.1 31.8 16 6.2 0.1 11.0 13 0 0 13 13 13 3 Leucine rich repeat RPA_interact_N PF14766.1 KLO17318.1 - 1.2 8.6 6.1 0.083 12.3 0.2 2.1 2 0 0 2 2 2 0 Replication protein A interacting N-terminal cobW PF02492.14 KLO17319.1 - 8.8e-33 113.2 0.0 1.1e-32 112.9 0.0 1.1 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain ArgK PF03308.11 KLO17319.1 - 9e-06 24.6 0.5 0.0006 18.6 0.0 2.1 2 0 0 2 2 2 2 ArgK protein AAA_17 PF13207.1 KLO17319.1 - 0.0068 17.2 0.1 0.021 15.6 0.0 1.9 2 1 0 2 2 2 1 AAA domain AAA_18 PF13238.1 KLO17319.1 - 0.017 15.4 0.0 0.028 14.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain GTP_EFTU PF00009.22 KLO17319.1 - 0.036 13.5 0.0 8.9 5.6 0.0 2.5 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain AAA_5 PF07728.9 KLO17319.1 - 0.065 12.9 0.0 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) TIP49 PF06068.8 KLO17319.1 - 0.096 11.3 0.0 0.14 10.8 0.0 1.2 1 0 0 1 1 1 0 TIP49 C-terminus ABC_tran PF00005.22 KLO17319.1 - 0.099 12.9 0.0 0.15 12.3 0.0 1.3 1 0 0 1 1 1 0 ABC transporter AAA_25 PF13481.1 KLO17319.1 - 0.13 11.6 0.1 0.24 10.7 0.1 1.4 1 1 0 1 1 1 0 AAA domain PBP PF01161.15 KLO17322.1 - 1.8e-16 60.2 0.0 2.7e-16 59.7 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein PBP PF01161.15 KLO17324.1 - 3.6e-13 49.5 0.4 6.2e-13 48.8 0.1 1.5 2 0 0 2 2 2 1 Phosphatidylethanolamine-binding protein Reo_sigmaC PF04582.7 KLO17328.1 - 0.056 12.6 13.0 0.29 10.2 2.5 2.4 2 1 0 2 2 2 0 Reovirus sigma C capsid protein V_ATPase_I PF01496.14 KLO17328.1 - 0.21 9.4 18.2 0.35 8.6 12.6 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Nucleoplasmin PF03066.10 KLO17328.1 - 9.7 5.6 16.3 27 4.2 11.3 1.7 1 0 0 1 1 1 0 Nucleoplasmin Tet_JBP PF12851.2 KLO17329.1 - 1.5e-05 24.3 0.0 2.2e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 Oxygenase domain of the 2OGFeDO superfamily DUF4218 PF13960.1 KLO17330.1 - 1.6e-05 24.3 0.1 2.8e-05 23.5 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4218) COXG PF06240.8 KLO17330.1 - 0.041 13.5 0.0 0.24 11.0 0.0 2.0 2 0 0 2 2 2 0 Carbon monoxide dehydrogenase subunit G (CoxG) PHA_gran_rgn PF09650.5 KLO17330.1 - 0.049 13.7 0.0 0.1 12.7 0.0 1.5 1 0 0 1 1 1 0 Putative polyhydroxyalkanoic acid system protein (PHA_gran_rgn) YibE_F PF07907.6 KLO17336.1 - 0.035 13.2 0.1 0.039 13.1 0.0 1.0 1 0 0 1 1 1 0 YibE/F-like protein Zn_clus PF00172.13 KLO17339.1 - 0.0081 16.0 11.4 0.015 15.1 7.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Zn_clus PF00172.13 KLO17340.1 - 0.11 12.4 13.0 0.17 11.8 9.0 1.3 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain UBN2 PF14223.1 KLO17341.1 - 1.1e-06 28.3 0.0 1.5e-06 28.0 0.0 1.1 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type zf-CCHC PF00098.18 KLO17341.1 - 5.7e-05 22.8 0.6 9.9e-05 22.0 0.4 1.4 1 0 0 1 1 1 1 Zinc knuckle UBN2_2 PF14227.1 KLO17341.1 - 0.00028 20.4 0.0 0.00038 19.9 0.0 1.1 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type PLAC8 PF04749.12 KLO17342.1 - 0.12 12.9 18.8 0.44 11.1 13.0 2.0 1 1 0 1 1 1 0 PLAC8 family DUF202 PF02656.10 KLO17343.1 - 3.9e-17 62.2 3.4 3.9e-17 62.2 2.3 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF202) Acyl-CoA_dh_2 PF08028.6 KLO17343.1 - 0.056 13.6 0.2 0.1 12.8 0.1 1.4 1 0 0 1 1 1 0 Acyl-CoA dehydrogenase, C-terminal domain YbgT_YccB PF08173.6 KLO17343.1 - 6.5 6.6 5.4 42 4.0 3.7 2.2 1 1 0 1 1 1 0 Membrane bound YbgT-like protein Hydrophobin PF01185.13 KLO17346.1 - 5.5e-13 49.1 4.3 6.9e-13 48.8 3.0 1.1 1 0 0 1 1 1 1 Fungal hydrophobin DUF2997 PF11211.3 KLO17346.1 - 0.2 11.0 1.1 3.4 7.1 0.1 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF2997) Sporozoite_P67 PF05642.6 KLO17346.1 - 1.3 6.7 3.7 1.5 6.5 2.5 1.0 1 0 0 1 1 1 0 Sporozoite P67 surface antigen CRAL_TRIO PF00650.15 KLO17347.1 - 2.4e-28 98.6 0.0 3.5e-28 98.0 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 KLO17347.1 - 6.1e-09 35.8 0.1 2.4e-08 33.9 0.0 2.1 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain ApoLp-III PF07464.6 KLO17347.1 - 0.049 13.6 0.2 3.8 7.5 0.0 2.7 3 0 0 3 3 3 0 Apolipophorin-III precursor (apoLp-III) Abhydrolase_6 PF12697.2 KLO17348.1 - 3e-26 92.7 1.4 3.6e-26 92.4 1.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KLO17348.1 - 5.3e-07 29.4 0.1 9.6e-07 28.6 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KLO17348.1 - 0.018 14.5 0.0 0.61 9.6 0.0 2.1 2 0 0 2 2 2 0 alpha/beta hydrolase fold RRM_1 PF00076.17 KLO17349.1 - 8.2e-08 31.7 0.0 2e-07 30.5 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KLO17349.1 - 6.4e-07 29.2 0.0 1.3e-06 28.3 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 KLO17349.1 - 8.7e-06 25.4 0.0 2e-05 24.2 0.0 1.7 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.6 KLO17349.1 - 2.5e-05 24.0 0.1 5.3e-05 23.0 0.0 1.6 1 0 0 1 1 1 1 RNA binding motif RRM_5 PF13893.1 KLO17349.1 - 0.00028 20.6 0.0 0.00058 19.6 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Mucin PF01456.12 KLO17349.1 - 0.39 10.4 7.7 0.69 9.6 5.3 1.4 1 0 0 1 1 1 0 Mucin-like glycoprotein Hus1 PF04005.7 KLO17351.1 - 5.9e-72 242.0 0.0 6.8e-72 241.8 0.0 1.0 1 0 0 1 1 1 1 Hus1-like protein Rad1 PF02144.11 KLO17351.1 - 7.7e-05 21.5 0.2 0.00036 19.4 0.1 2.0 2 0 0 2 2 2 1 Repair protein Rad1/Rec1/Rad17 Isochorismatase PF00857.15 KLO17352.1 - 4.1e-13 49.6 0.0 6e-13 49.1 0.0 1.2 1 0 0 1 1 1 1 Isochorismatase family Glutaredoxin PF00462.19 KLO17355.1 - 2.1e-19 69.2 0.0 2.2e-16 59.5 0.0 2.6 2 0 0 2 2 2 2 Glutaredoxin Thioredoxin PF00085.15 KLO17355.1 - 2.5e-14 52.7 0.0 5.2e-14 51.7 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.1 KLO17355.1 - 1.1e-05 25.3 0.0 0.0015 18.6 0.0 2.4 1 1 1 2 2 2 1 Thioredoxin-like Thioredoxin_3 PF13192.1 KLO17355.1 - 8e-05 22.3 0.0 0.00024 20.8 0.0 1.8 1 0 0 1 1 1 1 Thioredoxin domain HyaE PF07449.6 KLO17355.1 - 0.00046 20.0 0.0 0.0032 17.3 0.0 2.2 2 0 0 2 2 2 1 Hydrogenase-1 expression protein HyaE Thioredoxin_2 PF13098.1 KLO17355.1 - 0.0037 17.4 0.0 0.073 13.2 0.0 2.6 1 1 1 2 2 2 1 Thioredoxin-like domain GST_N_3 PF13417.1 KLO17355.1 - 0.085 13.0 0.0 0.22 11.7 0.0 1.7 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain TraF PF13728.1 KLO17355.1 - 0.12 11.8 0.0 0.42 10.0 0.0 1.9 2 0 0 2 2 2 0 F plasmid transfer operon protein Ku PF02735.11 KLO17356.1 - 7.8e-26 90.7 0.0 2.4e-25 89.1 0.0 1.8 1 1 0 1 1 1 1 Ku70/Ku80 beta-barrel domain Ku_N PF03731.10 KLO17356.1 - 1.1e-22 80.5 0.0 1.6e-22 80.0 0.0 1.3 1 0 0 1 1 1 1 Ku70/Ku80 N-terminal alpha/beta domain SAP PF02037.22 KLO17356.1 - 6e-10 38.3 0.1 1.1e-09 37.4 0.1 1.5 1 0 0 1 1 1 1 SAP domain Ku_C PF03730.9 KLO17356.1 - 6.4e-07 29.8 0.1 1.5e-06 28.6 0.1 1.7 1 0 0 1 1 1 1 Ku70/Ku80 C-terminal arm VWA_2 PF13519.1 KLO17356.1 - 6.1e-05 23.1 0.0 0.00029 21.0 0.0 2.1 2 2 0 2 2 2 1 von Willebrand factor type A domain Ish1 PF10281.4 KLO17356.1 - 0.077 13.0 0.5 0.29 11.2 0.0 2.2 2 0 0 2 2 2 0 Putative stress-responsive nuclear envelope protein HeH PF12949.2 KLO17356.1 - 0.23 11.0 0.9 0.89 9.1 0.1 2.3 2 1 0 2 2 2 0 HeH/LEM domain Cupin_2 PF07883.6 KLO17357.1 - 2.1e-26 91.1 0.3 3.3e-12 45.7 0.0 2.3 2 0 0 2 2 2 2 Cupin domain Cupin_1 PF00190.17 KLO17357.1 - 5.1e-26 90.8 0.0 8.7e-13 47.9 0.0 2.2 2 0 0 2 2 2 2 Cupin Cupin_3 PF05899.7 KLO17357.1 - 3.6e-07 29.4 0.1 0.013 14.8 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF861) AraC_binding PF02311.14 KLO17357.1 - 6.2e-06 25.9 0.2 0.0027 17.3 0.0 2.3 2 0 0 2 2 2 2 AraC-like ligand binding domain GPI PF06560.6 KLO17357.1 - 0.00035 19.6 0.0 0.00058 18.9 0.0 1.2 1 0 0 1 1 1 1 Glucose-6-phosphate isomerase (GPI) MannoseP_isomer PF01050.13 KLO17357.1 - 0.0013 18.3 0.0 0.0092 15.6 0.0 2.0 2 0 0 2 2 2 1 Mannose-6-phosphate isomerase Cupin_2 PF07883.6 KLO17358.1 - 5.8e-26 89.8 0.4 6.3e-12 44.8 0.0 2.3 2 0 0 2 2 2 2 Cupin domain Cupin_1 PF00190.17 KLO17358.1 - 3e-24 85.0 0.1 7.2e-11 41.7 0.0 2.2 2 0 0 2 2 2 2 Cupin Cupin_3 PF05899.7 KLO17358.1 - 2e-08 33.5 0.1 0.0065 15.8 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF861) AraC_binding PF02311.14 KLO17358.1 - 0.00011 21.8 0.3 0.023 14.3 0.0 2.4 2 0 0 2 2 2 2 AraC-like ligand binding domain MannoseP_isomer PF01050.13 KLO17358.1 - 0.00067 19.3 0.0 0.017 14.7 0.0 2.1 2 0 0 2 2 2 1 Mannose-6-phosphate isomerase GPI PF06560.6 KLO17358.1 - 0.003 16.5 0.0 0.0052 15.8 0.0 1.3 1 0 0 1 1 1 1 Glucose-6-phosphate isomerase (GPI) Cupin_4 PF08007.7 KLO17358.1 - 0.061 12.5 0.1 2.5 7.2 0.0 2.1 2 0 0 2 2 2 0 Cupin superfamily protein UCH PF00443.24 KLO17359.1 - 6.3e-60 202.5 2.3 8.6e-60 202.1 1.6 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 KLO17359.1 - 5e-28 98.3 1.8 8.1e-28 97.7 1.3 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.14 KLO17359.1 - 7.2e-12 45.2 8.4 7.2e-12 45.2 5.8 2.4 2 0 0 2 2 2 1 Zn-finger in ubiquitin-hydrolases and other protein SCP2 PF02036.12 KLO17360.1 - 2.6e-26 91.8 1.3 3.2e-26 91.5 0.9 1.1 1 0 0 1 1 1 1 SCP-2 sterol transfer family Alkyl_sulf_C PF14864.1 KLO17360.1 - 5.4e-06 26.4 0.9 7.1e-06 26.0 0.6 1.2 1 0 0 1 1 1 1 Alkyl sulfatase C-terminal Dynamin_N PF00350.18 KLO17361.1 - 3.5e-42 144.0 0.0 7e-42 143.0 0.0 1.5 1 0 0 1 1 1 1 Dynamin family Dynamin_M PF01031.15 KLO17361.1 - 3.7e-12 45.6 0.0 1.8e-11 43.3 0.0 2.0 2 0 0 2 2 2 1 Dynamin central region MMR_HSR1 PF01926.18 KLO17361.1 - 0.00076 19.4 0.0 0.0024 17.7 0.0 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 KLO17361.1 - 0.0011 19.4 0.1 0.0073 16.7 0.0 2.4 2 0 0 2 2 2 1 Miro-like protein AAA_23 PF13476.1 KLO17361.1 - 0.049 13.9 0.1 17 5.6 0.0 3.1 2 1 0 2 2 2 0 AAA domain ABC_tran PF00005.22 KLO17361.1 - 0.058 13.6 0.0 0.28 11.4 0.0 2.1 1 0 0 1 1 1 0 ABC transporter AAA_16 PF13191.1 KLO17361.1 - 0.08 12.9 0.1 0.6 10.0 0.0 2.4 2 0 0 2 2 2 0 AAA ATPase domain AAA_21 PF13304.1 KLO17361.1 - 0.1 12.5 0.4 0.28 11.1 0.0 1.9 2 0 0 2 2 2 0 AAA domain PTPA PF03095.10 KLO17362.1 - 9.2e-91 304.1 0.0 1.1e-90 303.8 0.0 1.1 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein DUF2517 PF10725.4 KLO17363.1 - 0.069 12.8 1.0 0.1 12.2 0.2 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2517) Orn_Arg_deC_N PF02784.11 KLO17364.1 - 3.4e-69 232.8 0.0 4.4e-69 232.4 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.17 KLO17364.1 - 2.4e-31 107.8 0.0 3.8e-31 107.2 0.0 1.3 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain KilA-N PF04383.8 KLO17365.1 - 0.00054 19.5 0.0 0.26 10.9 0.0 2.2 2 0 0 2 2 2 2 KilA-N domain SPX PF03105.14 KLO17367.1 - 1.9e-35 123.0 0.2 3.1e-35 122.3 0.2 1.4 1 0 0 1 1 1 1 SPX domain Na_sulph_symp PF00939.14 KLO17367.1 - 1.8e-27 96.3 17.9 1.8e-27 96.3 12.4 1.6 1 1 0 1 1 1 1 Sodium:sulfate symporter transmembrane region CitMHS PF03600.11 KLO17367.1 - 2.6e-10 39.4 11.7 2.6e-10 39.4 8.1 2.5 1 1 1 2 2 2 1 Citrate transporter SAM_2 PF07647.12 KLO17368.1 - 0.023 14.5 0.0 0.2 11.5 0.0 2.2 2 0 0 2 2 2 0 SAM domain (Sterile alpha motif) UPF0086 PF01868.11 KLO17369.1 - 6.8e-22 76.9 0.1 7.6e-21 73.5 0.0 2.4 3 0 0 3 3 3 1 Domain of unknown function UPF0086 APS_kinase PF01583.15 KLO17369.1 - 0.086 12.5 0.0 0.14 11.8 0.0 1.3 1 0 0 1 1 1 0 Adenylylsulphate kinase ADH_N PF08240.7 KLO17370.1 - 2.2e-18 65.9 0.1 4.4e-18 65.0 0.1 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KLO17370.1 - 5.2e-18 64.8 0.0 1.1e-17 63.7 0.0 1.5 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 KLO17370.1 - 0.12 13.2 0.0 0.29 12.0 0.0 1.6 1 0 0 1 1 1 0 Zinc-binding dehydrogenase DHDPS PF00701.17 KLO17371.1 - 6.9e-40 136.4 0.0 9.3e-40 136.0 0.0 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family Med22 PF06179.7 KLO17372.1 - 1.5e-17 63.6 0.5 2.3e-17 62.9 0.4 1.2 1 0 0 1 1 1 1 Surfeit locus protein 5 subunit 22 of Mediator complex PMC2NT PF08066.7 KLO17372.1 - 0.0014 18.8 1.8 0.18 12.1 0.0 2.1 1 1 1 2 2 2 2 PMC2NT (NUC016) domain ATP-synt_B PF00430.13 KLO17372.1 - 0.39 10.5 5.7 0.77 9.5 1.4 2.3 2 0 0 2 2 2 0 ATP synthase B/B' CF(0) SIMPL PF04402.9 KLO17372.1 - 0.78 9.5 3.6 0.66 9.7 1.7 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF541) Ribosomal_S13 PF00416.17 KLO17373.1 - 1.2e-39 134.9 1.5 1.5e-39 134.7 1.1 1.1 1 0 0 1 1 1 1 Ribosomal protein S13/S18 FbpA PF05833.6 KLO17373.1 - 0.0058 15.2 0.0 0.006 15.1 0.0 1.2 1 0 0 1 1 1 1 Fibronectin-binding protein A N-terminus (FbpA) HHH_6 PF14579.1 KLO17373.1 - 0.08 12.9 0.1 0.2 11.6 0.0 1.8 2 0 0 2 2 2 0 Helix-hairpin-helix motif ADH_N PF08240.7 KLO17374.1 - 4.4e-23 81.1 7.3 9.2e-23 80.0 5.0 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KLO17374.1 - 1.3e-15 57.1 0.0 2.1e-15 56.3 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 KLO17374.1 - 3.9e-05 22.8 0.2 8.3e-05 21.8 0.1 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.16 KLO17374.1 - 0.0061 16.1 0.0 0.012 15.2 0.0 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain zf-CCCH PF00642.19 KLO17375.1 - 1.4e-17 62.9 24.8 4.6e-05 22.9 0.4 4.5 3 1 1 4 4 4 4 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCHC PF00098.18 KLO17375.1 - 0.00071 19.3 4.1 0.0029 17.4 2.8 2.2 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_3 PF13917.1 KLO17375.1 - 0.008 15.8 0.1 0.019 14.6 0.1 1.7 1 0 0 1 1 1 1 Zinc knuckle zf-CCCH_2 PF14608.1 KLO17375.1 - 0.028 14.3 0.3 0.028 14.3 0.2 5.3 5 0 0 5 5 5 0 Zinc finger C-x8-C-x5-C-x3-H type BUD22 PF09073.5 KLO17376.1 - 9.9 5.0 13.4 13 4.7 9.3 1.1 1 0 0 1 1 1 0 BUD22 Thg1C PF14413.1 KLO17377.1 - 1.2e-46 157.3 0.1 1.8e-46 156.7 0.1 1.3 1 0 0 1 1 1 1 Thg1 C terminal domain Thg1 PF04446.7 KLO17377.1 - 1.7e-43 147.4 0.0 2.9e-43 146.7 0.0 1.4 1 0 0 1 1 1 1 tRNAHis guanylyltransferase COPIIcoated_ERV PF07970.7 KLO17378.1 - 1.4e-36 126.2 0.1 2.1e-36 125.6 0.1 1.2 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.1 KLO17378.1 - 6.3e-19 67.7 0.0 1.2e-18 66.8 0.0 1.4 1 0 0 1 1 1 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) zf-C3HC4_2 PF13923.1 KLO17379.1 - 1.5e-10 40.9 5.4 2.6e-10 40.1 3.8 1.4 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KLO17379.1 - 8.4e-10 38.1 7.3 1.2e-09 37.6 5.0 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KLO17379.1 - 8.5e-09 34.9 4.7 1.6e-08 34.0 3.3 1.4 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KLO17379.1 - 3.5e-08 33.1 9.5 4.9e-08 32.6 6.6 1.2 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 KLO17379.1 - 1.7e-06 27.6 9.4 3.9e-06 26.4 6.5 1.6 1 1 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 KLO17379.1 - 0.0006 19.6 9.8 0.0026 17.5 3.5 2.3 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 KLO17379.1 - 0.0028 17.3 6.3 0.02 14.6 2.4 2.4 2 0 0 2 2 2 1 RING-type zinc-finger DUF1644 PF07800.7 KLO17379.1 - 0.22 11.3 8.0 1.3 8.8 0.1 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1644) DUF566 PF04484.7 KLO17379.1 - 0.6 9.5 2.8 0.6 9.5 1.9 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF566) Maf PF02545.9 KLO17380.1 - 1.3e-40 138.5 0.0 1.5e-22 79.7 0.0 2.0 2 0 0 2 2 2 2 Maf-like protein MutS_I PF01624.15 KLO17380.1 - 0.067 13.2 0.0 3 7.9 0.0 2.3 2 0 0 2 2 2 0 MutS domain I ADH_zinc_N PF00107.21 KLO17380.1 - 0.14 11.6 0.0 0.25 10.9 0.0 1.4 1 0 0 1 1 1 0 Zinc-binding dehydrogenase DnaJ PF00226.26 KLO17381.1 - 6.6e-22 77.0 0.4 6.6e-22 77.0 0.3 2.4 3 0 0 3 3 3 1 DnaJ domain TPR_11 PF13414.1 KLO17381.1 - 5.9e-17 61.0 7.2 1.7e-10 40.3 0.1 5.2 6 0 0 6 6 6 3 TPR repeat TPR_1 PF00515.23 KLO17381.1 - 1.2e-13 50.0 0.1 0.00031 20.1 0.0 5.6 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_2 PF07719.12 KLO17381.1 - 1.2e-12 46.6 11.3 0.024 14.5 0.0 7.1 8 0 0 8 8 8 4 Tetratricopeptide repeat TPR_16 PF13432.1 KLO17381.1 - 6.5e-11 42.5 16.1 1.1e-06 29.1 0.1 5.5 2 2 4 6 6 6 3 Tetratricopeptide repeat TPR_19 PF14559.1 KLO17381.1 - 2.8e-10 40.3 10.1 0.039 14.2 0.0 6.2 5 1 1 6 6 6 3 Tetratricopeptide repeat TPR_14 PF13428.1 KLO17381.1 - 3.2e-08 33.4 11.6 0.25 12.0 0.0 6.7 6 1 0 6 6 5 3 Tetratricopeptide repeat TPR_6 PF13174.1 KLO17381.1 - 4.1e-08 33.1 9.2 3.1 8.4 0.1 6.9 7 1 0 7 7 6 2 Tetratricopeptide repeat TPR_12 PF13424.1 KLO17381.1 - 9.4e-08 31.8 4.3 0.007 16.2 0.0 5.0 2 2 2 4 4 4 1 Tetratricopeptide repeat TPR_8 PF13181.1 KLO17381.1 - 1.7e-07 30.5 5.7 0.019 14.7 0.1 5.0 4 1 1 5 5 4 1 Tetratricopeptide repeat Apc3 PF12895.2 KLO17381.1 - 2.6e-06 27.4 6.3 8.2e-05 22.6 0.0 3.9 5 0 0 5 5 4 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.1 KLO17381.1 - 2.9e-06 27.0 10.9 0.036 13.9 0.0 5.3 3 2 1 4 4 4 3 Tetratricopeptide repeat TPR_17 PF13431.1 KLO17381.1 - 5.6e-06 26.1 0.2 0.052 13.7 0.0 4.5 4 1 0 4 4 4 1 Tetratricopeptide repeat Apc5 PF12862.2 KLO17381.1 - 0.00074 19.3 5.3 0.9 9.4 0.0 4.8 4 1 1 5 5 5 1 Anaphase-promoting complex subunit 5 TPR_7 PF13176.1 KLO17381.1 - 0.0011 18.5 5.5 3.7 7.5 0.0 5.4 5 1 0 5 5 5 1 Tetratricopeptide repeat TIP49 PF06068.8 KLO17382.1 - 8.3e-175 581.2 0.1 9.5e-175 581.0 0.1 1.0 1 0 0 1 1 1 1 TIP49 C-terminus AAA PF00004.24 KLO17382.1 - 1.7e-09 38.0 0.0 4e-06 27.0 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 KLO17382.1 - 1.8e-09 37.0 0.5 1.6e-07 30.5 0.0 2.7 2 1 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 KLO17382.1 - 7.1e-06 26.1 0.0 0.00012 22.1 0.0 2.3 1 1 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.9 KLO17382.1 - 4.2e-05 23.2 0.1 0.028 14.1 0.0 2.4 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 KLO17382.1 - 7.4e-05 22.8 0.3 0.24 11.5 0.1 2.6 1 1 1 2 2 2 2 AAA domain AAA_33 PF13671.1 KLO17382.1 - 0.0003 20.6 0.0 0.2 11.5 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.1 KLO17382.1 - 0.00057 19.5 0.0 0.0021 17.7 0.0 2.0 1 0 0 1 1 1 1 Part of AAA domain AAA_25 PF13481.1 KLO17382.1 - 0.003 16.9 0.0 0.0058 16.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.1 KLO17382.1 - 0.0045 16.9 0.1 0.012 15.5 0.1 1.8 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 KLO17382.1 - 0.0071 15.4 0.1 0.024 13.7 0.1 1.8 2 0 0 2 2 2 1 Zeta toxin IstB_IS21 PF01695.12 KLO17382.1 - 0.009 15.4 0.1 0.017 14.5 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein Sigma54_activat PF00158.21 KLO17382.1 - 0.033 13.6 0.0 2.7 7.4 0.0 2.5 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_14 PF13173.1 KLO17382.1 - 0.039 13.8 0.0 8.5 6.2 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.1 KLO17382.1 - 0.042 14.6 0.0 0.12 13.2 0.0 1.8 2 0 0 2 2 1 0 AAA domain Mg_chelatase PF01078.16 KLO17382.1 - 0.049 12.7 0.1 0.24 10.5 0.0 1.9 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI DUF2075 PF09848.4 KLO17382.1 - 0.05 12.5 0.0 0.073 12.0 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_18 PF13238.1 KLO17382.1 - 0.051 13.8 0.1 0.18 12.1 0.0 1.9 2 0 0 2 2 2 0 AAA domain Parvo_NS1 PF01057.12 KLO17382.1 - 0.15 10.9 0.0 0.26 10.1 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 PhoH PF02562.11 KLO17382.1 - 0.37 10.0 2.9 0.67 9.1 0.0 2.7 4 0 0 4 4 4 0 PhoH-like protein MBOAT PF03062.14 KLO17383.1 - 7e-45 153.5 24.6 1.3e-44 152.6 17.1 1.4 1 0 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family WTF PF03303.8 KLO17383.1 - 3.5 6.9 5.8 0.43 9.9 0.3 2.2 2 1 0 2 2 2 0 WTF protein Aminotran_1_2 PF00155.16 KLO17384.1 - 2.4e-35 122.1 0.0 3.5e-35 121.6 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Cyclin_C PF02984.14 KLO17384.1 - 0.037 13.9 0.1 0.075 12.9 0.1 1.4 1 0 0 1 1 1 0 Cyclin, C-terminal domain DegT_DnrJ_EryC1 PF01041.12 KLO17384.1 - 0.17 10.8 0.0 0.35 9.8 0.0 1.5 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family RNase_P_Rpp14 PF01900.14 KLO17385.1 - 2e-26 91.9 0.0 2.6e-26 91.6 0.0 1.1 1 0 0 1 1 1 1 Rpp14/Pop5 family SPA PF08616.5 KLO17387.1 - 2.5e-05 23.9 0.1 5e-05 22.9 0.1 1.4 1 0 0 1 1 1 1 Stabilization of polarity axis DENN PF02141.16 KLO17387.1 - 0.068 12.8 0.0 0.22 11.1 0.0 2.0 1 1 0 1 1 1 0 DENN (AEX-3) domain CK_II_beta PF01214.13 KLO17388.1 - 1.6e-71 239.6 0.0 2e-71 239.3 0.0 1.1 1 0 0 1 1 1 1 Casein kinase II regulatory subunit DUF4139 PF13598.1 KLO17389.1 - 9.6e-67 225.5 1.7 5e-43 147.6 0.2 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF4139) DUF4140 PF13600.1 KLO17389.1 - 2.1e-12 47.4 0.4 4.4e-11 43.1 0.0 2.5 2 0 0 2 2 2 1 N-terminal domain of unknown function (DUF4140) Nucleoporin_FG PF13634.1 KLO17389.1 - 2.4e-05 24.5 26.2 2.4e-05 24.5 18.2 2.8 2 1 1 3 3 3 2 Nucleoporin FG repeat region FAD_binding_1 PF00667.15 KLO17390.1 - 9.9e-39 133.0 0.0 1.4e-38 132.5 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.20 KLO17390.1 - 3.5e-27 95.1 0.0 7e-27 94.1 0.0 1.5 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.16 KLO17390.1 - 2.4e-10 40.9 0.0 6.6e-10 39.5 0.0 1.8 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.19 KLO17390.1 - 0.061 13.4 0.0 0.29 11.3 0.0 2.0 2 0 0 2 2 2 0 Oxidoreductase FAD-binding domain Peptidase_M48 PF01435.13 KLO17391.1 - 3.6e-18 65.9 0.0 6.8e-18 65.0 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M48 Peptidase_MA_2 PF13485.1 KLO17391.1 - 0.039 13.9 0.0 0.14 12.1 0.0 1.9 2 0 0 2 2 2 0 Peptidase MA superfamily AA_permease_2 PF13520.1 KLO17392.1 - 1.3e-66 224.9 35.6 1.6e-66 224.6 24.7 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 KLO17392.1 - 1.8e-18 66.2 34.1 2.5e-18 65.7 23.6 1.2 1 0 0 1 1 1 1 Amino acid permease DUF2839 PF10999.3 KLO17392.1 - 0.0021 18.0 0.5 0.024 14.6 0.0 2.8 2 0 0 2 2 2 1 Protein of unknown function (DUF2839) 3D PF06725.6 KLO17393.1 - 0.019 14.9 0.7 9.5 6.2 0.0 2.9 2 0 0 2 2 2 0 3D domain CoA_transf_3 PF02515.12 KLO17395.1 - 6.2e-44 149.5 0.0 7.8e-44 149.1 0.0 1.1 1 0 0 1 1 1 1 CoA-transferase family III Polysacc_deac_1 PF01522.16 KLO17396.1 - 1.6e-28 98.7 0.0 3.1e-28 97.8 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide deacetylase COX5B PF01215.14 KLO17397.1 - 1.2e-34 118.8 0.0 1.5e-34 118.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Vb zf-C2H2_3 PF13878.1 KLO17397.1 - 0.003 17.0 0.5 0.0055 16.2 0.4 1.4 1 0 0 1 1 1 1 zinc-finger of acetyl-transferase ESCO PMI_typeI PF01238.16 KLO17398.1 - 1.7e-111 372.8 0.0 1.9e-111 372.6 0.0 1.0 1 0 0 1 1 1 1 Phosphomannose isomerase type I Cupin_2 PF07883.6 KLO17398.1 - 5.9e-05 22.4 0.2 0.1 12.1 0.1 2.3 2 0 0 2 2 2 2 Cupin domain AraC_binding PF02311.14 KLO17398.1 - 0.031 13.9 0.0 4 7.1 0.0 2.7 3 0 0 3 3 3 0 AraC-like ligand binding domain UPF0061 PF02696.9 KLO17399.1 - 6.6e-91 305.0 0.0 7.6e-90 301.5 0.0 2.0 1 1 0 1 1 1 1 Uncharacterized ACR, YdiU/UPF0061 family Transglut_i_TM PF14400.1 KLO17400.1 - 0.0097 15.4 0.5 0.019 14.4 0.2 1.6 1 1 0 1 1 1 1 Inactive transglutaminase fused to 7 transmembrane helices DUF3972 PF13118.1 KLO17400.1 - 0.062 13.3 1.4 0.11 12.5 1.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3972) AMP-binding PF00501.23 KLO17402.1 - 1.8e-74 250.6 0.0 2.3e-74 250.2 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme DUF2917 PF11142.3 KLO17402.1 - 0.13 11.4 0.4 0.5 9.5 0.3 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2917) GH3 PF03321.8 KLO17402.1 - 0.23 9.9 0.0 15 3.9 0.0 2.1 2 0 0 2 2 2 0 GH3 auxin-responsive promoter V_ATPase_I PF01496.14 KLO17403.1 - 0.014 13.2 3.7 0.022 12.6 2.6 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Peptidase_S64 PF08192.6 KLO17403.1 - 0.41 8.9 3.8 0.16 10.3 0.2 1.8 2 0 0 2 2 2 0 Peptidase family S64 DUF342 PF03961.8 KLO17403.1 - 0.47 8.8 3.4 0.95 7.7 2.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Snapin_Pallidin PF14712.1 KLO17403.1 - 0.87 9.9 6.2 0.75 10.1 2.0 2.7 2 1 1 3 3 3 0 Snapin/Pallidin Atg14 PF10186.4 KLO17403.1 - 1.4 7.7 12.8 0.025 13.5 3.8 1.8 2 0 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 DUF1192 PF06698.6 KLO17403.1 - 1.5 8.7 10.3 9.6 6.1 0.1 3.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) TMF_DNA_bd PF12329.3 KLO17403.1 - 1.7 8.5 12.0 31 4.4 3.8 3.9 2 2 0 2 2 2 0 TATA element modulatory factor 1 DNA binding DivIC PF04977.10 KLO17403.1 - 9 5.8 8.5 7.2 6.1 2.0 3.2 2 1 1 3 3 3 0 Septum formation initiator Metallophos PF00149.23 KLO17405.1 - 8.6e-42 142.8 0.9 1.1e-41 142.4 0.6 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase cwf21 PF08312.7 KLO17405.1 - 0.23 11.3 1.1 0.52 10.2 0.7 1.6 1 0 0 1 1 1 0 cwf21 domain Cpn60_TCP1 PF00118.19 KLO17406.1 - 3.9e-141 470.9 0.6 4.5e-141 470.8 0.4 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family AP_endonuc_2 PF01261.19 KLO17406.1 - 0.095 11.9 0.0 0.26 10.5 0.0 1.7 2 0 0 2 2 2 0 Xylose isomerase-like TIM barrel IncA PF04156.9 KLO17407.1 - 0.56 9.7 10.9 1.1 8.8 7.5 1.5 1 0 0 1 1 1 0 IncA protein TMF_DNA_bd PF12329.3 KLO17407.1 - 2.5 7.9 9.3 8.9 6.2 3.7 2.8 2 1 1 3 3 3 0 TATA element modulatory factor 1 DNA binding Sad1_UNC PF07738.8 KLO17409.1 - 3.3e-24 85.2 0.0 2.2e-11 43.6 0.0 2.6 1 1 1 2 2 2 2 Sad1 / UNC-like C-terminal Abhydrolase_1 PF00561.15 KLO17410.1 - 3.2e-35 121.7 0.0 4.4e-35 121.3 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 KLO17410.1 - 4.5e-28 98.6 0.0 6.8e-28 98.1 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KLO17410.1 - 5.2e-15 55.4 0.0 4.5e-14 52.4 0.0 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_4 PF08386.5 KLO17410.1 - 0.00052 19.8 0.0 0.0009 19.0 0.0 1.3 1 0 0 1 1 1 1 TAP-like protein Peptidase_S9 PF00326.16 KLO17410.1 - 0.001 18.3 0.0 0.46 9.6 0.0 2.3 2 0 0 2 2 2 2 Prolyl oligopeptidase family Peptidase_S15 PF02129.13 KLO17410.1 - 0.0025 17.2 0.0 0.0049 16.3 0.0 1.5 1 1 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Ndr PF03096.9 KLO17410.1 - 0.0093 14.4 0.0 0.015 13.8 0.0 1.3 1 0 0 1 1 1 1 Ndr family Hydrolase_4 PF12146.3 KLO17410.1 - 0.031 14.1 0.0 0.067 13.0 0.0 1.6 1 0 0 1 1 1 0 Putative lysophospholipase HECT PF00632.20 KLO17411.1 - 6.5e-92 308.0 0.0 8.7e-92 307.6 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) WW PF00397.21 KLO17411.1 - 4.1e-34 116.0 22.2 1.5e-11 43.9 4.1 3.5 3 0 0 3 3 3 3 WW domain C2 PF00168.25 KLO17411.1 - 1.2e-16 60.3 0.2 2.9e-16 59.0 0.1 1.7 1 0 0 1 1 1 1 C2 domain RRM_1 PF00076.17 KLO17412.1 - 5.6e-14 51.5 0.0 1.1e-13 50.5 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KLO17412.1 - 4.2e-12 45.8 0.0 8.5e-12 44.8 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KLO17412.1 - 1.9e-08 34.0 0.0 3.6e-08 33.1 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SNAPc19 PF15497.1 KLO17412.1 - 1.4 9.1 5.5 0.35 11.1 1.1 1.9 2 0 0 2 2 2 0 snRNA-activating protein complex subunit 19, SNAPc subunit 19 CRAL_TRIO PF00650.15 KLO17413.1 - 4.7e-27 94.4 0.0 7.5e-27 93.7 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 KLO17413.1 - 5e-11 42.5 0.1 1e-10 41.5 0.1 1.5 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.1 KLO17413.1 - 0.0025 17.7 0.0 0.004 17.0 0.0 1.3 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain DUF684 PF05075.9 KLO17413.1 - 0.013 14.1 0.0 0.2 10.1 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF684) UBA_4 PF14555.1 KLO17413.1 - 0.18 11.3 0.4 0.93 9.0 0.0 2.1 2 0 0 2 2 2 0 UBA-like domain MFS_1 PF07690.11 KLO17415.1 - 6.5e-22 77.7 49.7 5.8e-15 54.8 16.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1228 PF06779.9 KLO17415.1 - 9.6e-05 22.3 7.6 0.04 13.9 0.2 2.8 2 0 0 2 2 2 2 Protein of unknown function (DUF1228) AAA PF00004.24 KLO17416.1 - 1.5e-41 141.7 0.0 2.5e-41 140.9 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_2 PF07724.9 KLO17416.1 - 1.8e-06 27.9 0.1 5e-06 26.5 0.0 1.7 2 0 0 2 2 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.1 KLO17416.1 - 2.9e-06 27.4 0.2 0.00058 20.0 0.1 2.4 1 1 0 1 1 1 1 AAA domain DUF815 PF05673.8 KLO17416.1 - 3.3e-05 22.9 0.0 5.9e-05 22.1 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_5 PF07728.9 KLO17416.1 - 0.00018 21.2 0.2 0.0012 18.5 0.2 2.3 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 KLO17416.1 - 0.00021 21.3 0.0 0.0015 18.5 0.0 2.1 1 1 0 1 1 1 1 AAA ATPase domain RuvB_N PF05496.7 KLO17416.1 - 0.00056 19.0 0.0 0.00097 18.2 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus KaiC PF06745.8 KLO17416.1 - 0.0021 17.2 0.4 0.13 11.3 0.0 2.8 2 1 1 3 3 3 1 KaiC AAA_14 PF13173.1 KLO17416.1 - 0.0025 17.7 0.0 0.0057 16.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 KLO17416.1 - 0.0027 18.5 0.7 0.016 15.9 0.1 2.4 2 1 0 2 2 2 1 AAA domain AAA_3 PF07726.6 KLO17416.1 - 0.0037 16.8 0.0 0.011 15.3 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.1 KLO17416.1 - 0.0069 16.2 0.0 0.015 15.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 KLO17416.1 - 0.0079 15.9 0.4 0.017 14.8 0.2 1.5 1 0 0 1 1 1 1 Part of AAA domain IstB_IS21 PF01695.12 KLO17416.1 - 0.014 14.8 0.0 0.026 13.9 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_18 PF13238.1 KLO17416.1 - 0.015 15.6 2.5 0.037 14.3 0.0 2.5 2 1 1 3 3 3 0 AAA domain Zeta_toxin PF06414.7 KLO17416.1 - 0.019 14.0 0.0 0.032 13.3 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin NACHT PF05729.7 KLO17416.1 - 0.02 14.5 0.1 0.43 10.2 0.1 2.6 2 1 1 3 3 3 0 NACHT domain AAA_28 PF13521.1 KLO17416.1 - 0.027 14.4 0.1 0.078 12.9 0.0 1.8 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.17 KLO17416.1 - 0.035 12.9 0.0 0.072 11.9 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain TIP49 PF06068.8 KLO17416.1 - 0.037 12.7 0.0 0.067 11.9 0.0 1.3 1 0 0 1 1 1 0 TIP49 C-terminus AAA_25 PF13481.1 KLO17416.1 - 0.06 12.7 0.8 1.9 7.8 0.2 2.5 1 1 1 2 2 2 0 AAA domain DUF2075 PF09848.4 KLO17416.1 - 0.072 12.0 0.0 0.11 11.4 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Viral_helicase1 PF01443.13 KLO17416.1 - 0.09 12.2 0.0 0.15 11.5 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase RNA_helicase PF00910.17 KLO17416.1 - 0.11 12.6 0.0 0.23 11.6 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AAA_24 PF13479.1 KLO17416.1 - 0.11 12.0 0.1 0.35 10.4 0.1 1.8 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.16 KLO17416.1 - 0.12 11.5 0.0 0.22 10.6 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI PhoH PF02562.11 KLO17416.1 - 0.13 11.4 0.1 0.35 10.0 0.1 1.6 2 0 0 2 2 2 0 PhoH-like protein Med26 PF08711.6 KLO17417.1 - 4.3e-10 38.9 0.0 1.6e-09 37.1 0.0 2.1 1 0 0 1 1 1 1 TFIIS helical bundle-like domain Mito_carr PF00153.22 KLO17420.1 - 2.1e-55 184.4 3.8 4.1e-21 74.4 0.2 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein Methyltransf_16 PF10294.4 KLO17421.1 - 1.2e-22 80.2 0.0 1.1e-17 64.0 0.0 2.1 2 0 0 2 2 2 2 Putative methyltransferase Methyltransf_32 PF13679.1 KLO17421.1 - 0.057 13.0 0.0 0.08 12.6 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain DisA-linker PF10635.4 KLO17421.1 - 0.1 12.0 0.0 0.17 11.3 0.0 1.4 1 0 0 1 1 1 0 DisA bacterial checkpoint controller linker region Methyltransf_31 PF13847.1 KLO17421.1 - 0.17 11.4 0.0 0.29 10.7 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Arrestin_N PF00339.24 KLO17422.1 - 4.4e-06 26.5 0.0 1.1e-05 25.3 0.0 1.6 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain Arrestin_N PF00339.24 KLO17423.1 - 5.1e-09 36.1 0.0 6.6e-07 29.2 0.0 2.5 2 0 0 2 2 2 2 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.17 KLO17423.1 - 0.0091 16.1 0.0 0.041 13.9 0.0 1.9 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.24 KLO17425.1 - 4.9e-05 23.1 0.1 0.0058 16.4 0.0 3.4 2 1 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain LDB19 PF13002.2 KLO17425.1 - 0.032 13.7 0.0 0.054 12.9 0.0 1.2 1 0 0 1 1 1 0 Arrestin_N terminal like Arrestin_N PF00339.24 KLO17426.1 - 2.7e-08 33.7 0.0 8.8e-05 22.3 0.0 3.2 3 0 0 3 3 3 2 Arrestin (or S-antigen), N-terminal domain G-alpha PF00503.15 KLO17427.1 - 2.6e-129 431.3 0.0 3e-129 431.1 0.0 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 KLO17427.1 - 4e-13 48.9 0.0 8.7e-10 38.1 0.0 2.5 2 0 0 2 2 2 2 ADP-ribosylation factor family Ras PF00071.17 KLO17427.1 - 0.001 18.4 0.1 0.13 11.6 0.0 2.7 3 0 0 3 3 3 1 Ras family AAA_29 PF13555.1 KLO17427.1 - 0.045 13.2 0.0 0.094 12.2 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain Gtr1_RagA PF04670.7 KLO17427.1 - 0.13 11.3 1.4 2 7.5 0.0 2.8 2 1 0 2 2 2 0 Gtr1/RagA G protein conserved region Pro_isomerase PF00160.16 KLO17428.1 - 4.7e-45 153.5 0.1 5.7e-45 153.3 0.1 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD F_actin_cap_B PF01115.12 KLO17429.1 - 5.6e-102 340.0 0.0 6.6e-102 339.8 0.0 1.0 1 0 0 1 1 1 1 F-actin capping protein, beta subunit Arrestin_N PF00339.24 KLO17430.1 - 5e-09 36.1 1.6 4.9e-08 32.9 0.0 3.0 3 1 0 3 3 3 1 Arrestin (or S-antigen), N-terminal domain Gtr1_RagA PF04670.7 KLO17431.1 - 2.9e-42 144.4 0.0 4.3e-42 143.8 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.5 KLO17431.1 - 8.5e-07 28.3 0.0 1.4e-06 27.6 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Arf PF00025.16 KLO17431.1 - 2.6e-05 23.5 0.0 4.3e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family Miro PF08477.8 KLO17431.1 - 4.6e-05 23.8 0.0 8.4e-05 23.0 0.0 1.5 1 0 0 1 1 1 1 Miro-like protein AAA_14 PF13173.1 KLO17431.1 - 0.0034 17.2 0.2 0.011 15.5 0.0 1.9 1 1 1 2 2 2 1 AAA domain Ras PF00071.17 KLO17431.1 - 0.13 11.6 0.0 0.24 10.7 0.0 1.5 1 0 0 1 1 1 0 Ras family DUF605 PF04652.11 KLO17431.1 - 0.17 11.2 18.6 0.39 10.0 12.9 1.5 1 0 0 1 1 1 0 Vta1 like XRCC4 PF06632.7 KLO17431.1 - 0.78 8.5 3.9 1.7 7.4 2.7 1.5 1 0 0 1 1 1 0 DNA double-strand break repair and V(D)J recombination protein XRCC4 TFIIA PF03153.8 KLO17431.1 - 2.9 7.6 7.5 5.6 6.7 5.2 1.5 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit G-alpha PF00503.15 KLO17431.1 - 7.9 5.0 9.6 0.26 9.9 0.2 2.7 3 0 0 3 3 3 0 G-protein alpha subunit VTC PF09359.5 KLO17432.1 - 2.8e-101 338.2 0.1 9.2e-101 336.5 0.0 1.9 2 0 0 2 2 2 1 VTC domain SPX PF03105.14 KLO17432.1 - 2.6e-23 83.1 17.4 7.5e-22 78.4 7.2 3.6 2 1 0 2 2 2 1 SPX domain DUF202 PF02656.10 KLO17432.1 - 2.2e-09 37.3 1.5 4.7e-09 36.3 1.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF202) PepSY_TM_1 PF13172.1 KLO17432.1 - 0.24 11.2 1.6 0.44 10.3 1.1 1.5 1 0 0 1 1 1 0 PepSY-associated TM helix FliE PF02049.13 KLO17432.1 - 1.1 9.3 10.1 0.49 10.4 0.2 2.8 3 0 0 3 3 3 0 Flagellar hook-basal body complex protein FliE VSP PF03302.8 KLO17433.1 - 2.1e-08 33.2 14.2 2.8e-08 32.8 9.9 1.1 1 0 0 1 1 1 1 Giardia variant-specific surface protein Herpes_BLLF1 PF05109.8 KLO17433.1 - 7.7e-05 20.8 36.7 9e-05 20.6 25.5 1.1 1 0 0 1 1 1 1 Herpes virus major outer envelope glycoprotein (BLLF1) DUF566 PF04484.7 KLO17433.1 - 1.4 8.3 17.5 1.9 7.8 12.2 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF566) SOG2 PF10428.4 KLO17433.1 - 2.2 6.8 29.6 3 6.3 20.5 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein TFIIA PF03153.8 KLO17433.1 - 3.3 7.5 11.0 5.5 6.7 7.6 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PTPlike_phytase PF14566.1 KLO17434.1 - 1.4e-120 398.3 0.0 3.7e-39 134.1 0.0 3.8 4 0 0 4 4 4 3 Inositol hexakisphosphate Y_phosphatase3 PF13350.1 KLO17434.1 - 7.1e-05 23.1 0.0 1.2 9.3 0.0 3.6 3 0 0 3 3 3 2 Tyrosine phosphatase family DSPc PF00782.15 KLO17434.1 - 9.4e-05 22.0 0.0 0.64 9.6 0.0 3.8 3 0 0 3 3 3 2 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 KLO17434.1 - 0.00012 21.4 0.0 0.056 12.7 0.0 3.2 3 0 0 3 3 3 1 Protein-tyrosine phosphatase TFIIE-A_C-term PF11521.3 KLO17434.1 - 0.0057 16.5 0.0 2.7 8.0 0.0 3.4 3 0 0 3 3 3 1 C-terminal general transcription factor TFIIE alpha THUMP PF02926.12 KLO17435.1 - 2.1e-08 34.1 0.8 5.6e-08 32.7 0.0 1.9 2 0 0 2 2 2 1 THUMP domain Cwf_Cwc_15 PF04889.7 KLO17435.1 - 0.036 13.7 0.4 0.056 13.1 0.3 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Glyco_trans_1_3 PF13528.1 KLO17436.1 - 2.5e-09 36.7 0.0 2e-08 33.8 0.0 2.0 2 0 0 2 2 2 1 Glycosyl transferase family 1 Ldh_1_N PF00056.18 KLO17436.1 - 0.02 14.6 0.0 0.04 13.7 0.0 1.4 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain p450 PF00067.17 KLO17437.1 - 5.5e-59 199.9 0.0 6.5e-59 199.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Spc97_Spc98 PF04130.8 KLO17438.1 - 1.7e-36 125.7 0.9 1.1e-35 123.0 0.6 2.1 1 1 0 1 1 1 1 Spc97 / Spc98 family RE_R_Pab1 PF09522.5 KLO17438.1 - 0.018 14.9 0.0 0.49 10.3 0.0 2.4 2 0 0 2 2 2 0 R.Pab1 restriction endonuclease RicinB_lectin_2 PF14200.1 KLO17439.1 - 0.026 14.8 0.0 0.16 12.3 0.0 2.0 2 0 0 2 2 2 0 Ricin-type beta-trefoil lectin domain-like Mdv1 PF11542.3 KLO17439.1 - 0.12 12.2 0.0 0.21 11.5 0.0 1.3 1 0 0 1 1 1 0 Mitochondrial division protein 1 p450 PF00067.17 KLO17440.1 - 3.6e-62 210.3 0.0 4.8e-62 209.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 KLO17442.1 - 6.7e-66 222.7 0.0 8.3e-66 222.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DSPc PF00782.15 KLO17443.1 - 9.4e-25 86.7 0.0 1.4e-22 79.6 0.0 2.8 2 1 0 2 2 2 2 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 KLO17443.1 - 0.0036 16.6 0.1 0.0066 15.8 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase ABC2_membrane PF01061.19 KLO17444.1 - 2.6e-31 108.4 19.5 2.6e-31 108.4 13.5 2.0 2 0 0 2 2 2 1 ABC-2 type transporter ABC_tran PF00005.22 KLO17444.1 - 2.2e-25 89.5 0.1 5.6e-25 88.2 0.0 1.8 2 0 0 2 2 2 1 ABC transporter AAA_21 PF13304.1 KLO17444.1 - 1.4e-08 35.0 0.0 7.2e-07 29.4 0.0 2.3 1 1 0 1 1 1 1 AAA domain ABC2_membrane_3 PF12698.2 KLO17444.1 - 0.00011 21.3 19.8 0.00011 21.3 13.7 1.8 1 1 1 2 2 2 1 ABC-2 family transporter protein hEGF PF12661.2 KLO17444.1 - 0.0015 18.4 23.5 0.039 14.0 2.3 4.1 3 0 0 3 3 3 2 Human growth factor-like EGF DUF258 PF03193.11 KLO17444.1 - 0.0049 16.0 0.0 0.012 14.7 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_25 PF13481.1 KLO17444.1 - 0.0049 16.3 0.0 0.24 10.7 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.1 KLO17444.1 - 0.045 13.2 0.1 0.11 12.0 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_16 PF13191.1 KLO17444.1 - 0.06 13.3 0.0 0.13 12.2 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain AAA_15 PF13175.1 KLO17444.1 - 0.17 10.9 0.0 10 5.0 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain AAA_28 PF13521.1 KLO17444.1 - 0.19 11.6 0.0 0.31 10.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain UPF0079 PF02367.12 KLO17444.1 - 0.22 11.1 0.0 0.4 10.3 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 EGF_2 PF07974.8 KLO17444.1 - 2.9 8.1 34.6 0.04 14.0 6.4 4.0 4 0 0 4 4 4 0 EGF-like domain Epimerase PF01370.16 KLO17445.1 - 2.7e-21 76.0 0.0 3.5e-21 75.7 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 KLO17445.1 - 4.3e-16 59.4 0.0 5.6e-16 59.0 0.0 1.1 1 0 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 KLO17445.1 - 1.6e-09 36.8 0.0 2.1e-09 36.5 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family TrkA_N PF02254.13 KLO17445.1 - 1e-06 28.7 0.0 1.5e-06 28.1 0.0 1.3 1 0 0 1 1 1 1 TrkA-N domain Polysacc_synt_2 PF02719.10 KLO17445.1 - 0.00013 20.9 0.0 0.0012 17.7 0.0 2.1 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein NmrA PF05368.8 KLO17445.1 - 0.00014 21.1 0.0 0.00019 20.7 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family RmlD_sub_bind PF04321.12 KLO17445.1 - 0.00061 18.7 0.0 0.0028 16.5 0.0 1.9 1 1 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.7 KLO17445.1 - 0.0029 16.5 0.0 0.08 11.8 0.0 2.1 2 0 0 2 2 2 1 Male sterility protein DapB_N PF01113.15 KLO17445.1 - 0.012 15.5 0.0 0.019 14.8 0.0 1.4 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus adh_short PF00106.20 KLO17445.1 - 0.049 13.5 0.6 0.16 11.9 0.4 1.8 1 1 0 1 1 1 0 short chain dehydrogenase Gp_dh_N PF00044.19 KLO17445.1 - 0.055 13.4 0.0 0.085 12.8 0.0 1.4 1 0 0 1 1 1 0 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain Neuropep_like PF15161.1 KLO17447.1 - 0.085 12.3 0.0 0.23 10.9 0.0 1.7 1 0 0 1 1 1 0 Neuropeptide-like F-box-like PF12937.2 KLO17448.1 - 3.6e-07 29.7 2.2 1e-06 28.3 1.5 1.9 1 1 0 1 1 1 1 F-box-like RC-P840_PscD PF10657.4 KLO17448.1 - 0.0021 17.8 0.0 0.0051 16.6 0.0 1.5 1 0 0 1 1 1 1 Photosystem P840 reaction centre protein PscD F-box PF00646.28 KLO17448.1 - 0.021 14.4 3.7 0.67 9.6 2.6 3.1 1 1 0 1 1 1 0 F-box domain F-box-like PF12937.2 KLO17449.1 - 4.5e-05 23.0 2.6 7.3e-05 22.4 0.2 2.7 3 0 0 3 3 3 1 F-box-like F-box-like PF12937.2 KLO17450.1 - 0.0014 18.2 0.1 0.0036 16.9 0.1 1.8 1 0 0 1 1 1 1 F-box-like F-box-like PF12937.2 KLO17451.1 - 8.3e-05 22.2 0.2 0.00028 20.5 0.1 2.0 1 0 0 1 1 1 1 F-box-like F-box-like PF12937.2 KLO17452.1 - 0.0017 18.0 2.0 0.0018 17.9 0.2 2.1 2 0 0 2 2 2 1 F-box-like zf-RVT PF13966.1 KLO17453.1 - 0.00072 19.8 0.5 0.0016 18.7 0.2 1.6 1 1 0 1 1 1 1 zinc-binding in reverse transcriptase RNase_H PF00075.19 KLO17453.1 - 0.0022 18.3 0.0 0.0042 17.4 0.0 1.4 1 0 0 1 1 1 1 RNase H RRM_6 PF14259.1 KLO17455.1 - 0.0068 16.3 0.0 0.014 15.3 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) zf-CCHC_6 PF15288.1 KLO17455.1 - 0.008 15.8 0.5 0.025 14.2 0.4 1.8 1 0 0 1 1 1 1 Zinc knuckle CcmH PF03918.9 KLO17455.1 - 0.14 11.1 3.8 1.7 7.6 0.2 3.3 4 0 0 4 4 4 0 Cytochrome C biogenesis protein PolC_DP2 PF03833.8 KLO17455.1 - 0.2 9.2 1.4 0.2 9.2 1.0 1.2 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 DUF2039 PF10217.4 KLO17455.1 - 0.64 10.0 11.6 0.15 12.0 4.9 2.0 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2039) Zn-ribbon_8 PF09723.5 KLO17455.1 - 6 6.9 12.6 23 5.0 3.3 3.2 2 1 1 3 3 3 0 Zinc ribbon domain F-box-like PF12937.2 KLO17457.1 - 0.001 18.7 0.1 0.0027 17.4 0.0 1.8 1 0 0 1 1 1 1 F-box-like LRR_8 PF13855.1 KLO17457.1 - 0.015 15.0 2.6 6.9 6.5 0.1 4.0 3 1 1 4 4 4 0 Leucine rich repeat LRR_6 PF13516.1 KLO17457.1 - 2.6 8.3 7.9 8.3 6.8 0.1 5.5 9 0 0 9 9 9 0 Leucine Rich repeat F-box-like PF12937.2 KLO17458.1 - 0.00044 19.9 0.1 0.0013 18.3 0.1 1.9 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KLO17458.1 - 0.51 10.0 6.1 0.2 11.3 1.7 2.3 2 0 0 2 2 2 0 F-box domain F-box-like PF12937.2 KLO17459.1 - 0.00058 19.5 0.4 0.0015 18.2 0.3 1.8 1 0 0 1 1 1 1 F-box-like F-box-like PF12937.2 KLO17460.1 - 0.015 15.0 1.9 0.015 15.0 1.3 2.9 4 1 0 4 4 4 0 F-box-like LRR_4 PF12799.2 KLO17460.1 - 0.95 9.1 4.6 0.81 9.3 0.1 2.9 3 0 0 3 3 3 0 Leucine Rich repeats (2 copies) F-box-like PF12937.2 KLO17464.1 - 3.4e-05 23.4 7.0 9.8e-05 21.9 4.9 1.8 1 1 0 1 1 1 1 F-box-like PRY PF13765.1 KLO17464.1 - 0.092 12.2 0.1 0.22 11.0 0.0 1.6 1 0 0 1 1 1 0 SPRY-associated domain F-box PF00646.28 KLO17464.1 - 3.1 7.5 5.9 8 6.2 1.4 3.0 2 1 1 3 3 3 0 F-box domain F-box-like PF12937.2 KLO17465.1 - 0.0025 17.4 0.7 0.0025 17.4 0.5 2.3 2 0 0 2 2 2 1 F-box-like F-box-like PF12937.2 KLO17467.1 - 0.026 14.2 6.8 0.23 11.1 4.7 2.5 1 1 0 1 1 1 0 F-box-like PMT PF02366.13 KLO17468.1 - 6.7e-78 261.4 14.6 6.7e-78 261.4 10.1 1.9 2 1 0 3 3 3 1 Dolichyl-phosphate-mannose-protein mannosyltransferase MIR PF02815.14 KLO17468.1 - 3.8e-45 153.7 0.5 6.6e-45 152.9 0.4 1.4 1 0 0 1 1 1 1 MIR domain DUF1240 PF06836.7 KLO17468.1 - 0.032 14.4 0.2 0.97 9.6 0.1 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF1240) Mito_carr PF00153.22 KLO17469.1 - 7.5e-59 195.4 0.3 2.7e-20 71.8 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF508 PF04370.7 KLO17469.1 - 0.076 12.6 2.0 0.75 9.4 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF508) Acyl-CoA_dh_1 PF00441.19 KLO17470.1 - 4.3e-45 153.4 3.4 6.1e-45 152.9 2.3 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 KLO17470.1 - 8e-29 100.5 0.4 1.8e-27 96.1 0.0 2.3 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.6 KLO17470.1 - 1.1e-22 80.6 2.1 1.9e-22 79.9 1.5 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 KLO17470.1 - 9.4e-18 63.4 0.0 1.9e-17 62.4 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_ox_N PF14749.1 KLO17470.1 - 0.023 15.0 0.0 0.05 13.8 0.0 1.7 1 1 0 1 1 1 0 Acyl-coenzyme A oxidase N-terminal BTB PF00651.26 KLO17471.1 - 0.0041 17.1 0.0 0.0077 16.2 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain Arf PF00025.16 KLO17472.1 - 5.6e-68 227.5 0.1 6.3e-68 227.4 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.15 KLO17472.1 - 1.1e-12 47.3 0.9 2.8e-07 29.5 0.1 2.4 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.7 KLO17472.1 - 6.5e-11 41.8 0.0 8.1e-11 41.5 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Ras PF00071.17 KLO17472.1 - 8.1e-10 38.3 0.0 9.8e-10 38.0 0.0 1.1 1 0 0 1 1 1 1 Ras family SRPRB PF09439.5 KLO17472.1 - 1.8e-09 37.0 0.0 2.4e-09 36.6 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.18 KLO17472.1 - 2.7e-08 33.7 0.0 5.9e-08 32.6 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 KLO17472.1 - 9.6e-07 29.3 0.0 1.4e-06 28.8 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein GTP_EFTU PF00009.22 KLO17472.1 - 1.5e-06 27.7 0.0 6.7e-05 22.4 0.0 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain Dynamin_N PF00350.18 KLO17472.1 - 0.023 14.5 0.1 0.053 13.3 0.1 1.6 1 1 1 2 2 2 0 Dynamin family cobW PF02492.14 KLO17472.1 - 0.047 13.1 0.1 1.2 8.5 0.0 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain NACHT PF05729.7 KLO17472.1 - 0.063 12.9 0.1 0.28 10.8 0.0 2.0 2 0 0 2 2 2 0 NACHT domain PduV-EutP PF10662.4 KLO17472.1 - 0.073 12.5 0.0 0.13 11.7 0.0 1.4 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_17 PF13207.1 KLO17472.1 - 0.11 13.3 0.0 0.16 12.7 0.0 1.6 1 1 0 1 1 1 0 AAA domain FeoB_N PF02421.13 KLO17472.1 - 0.12 11.6 0.3 0.22 10.7 0.2 1.8 1 1 0 1 1 1 0 Ferrous iron transport protein B GTP_EFTU PF00009.22 KLO17473.1 - 2.1e-31 108.8 0.0 1.3e-30 106.2 0.0 2.3 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain IF-2 PF11987.3 KLO17473.1 - 1.1e-15 57.4 0.2 9.5e-15 54.4 0.0 2.4 2 0 0 2 2 2 1 Translation-initiation factor 2 GTP_EFTU_D2 PF03144.20 KLO17473.1 - 2.7e-13 49.8 6.6 5.7e-10 39.1 0.1 3.1 3 0 0 3 3 3 2 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 KLO17473.1 - 2.2e-07 30.8 0.1 7.5e-07 29.1 0.0 2.0 1 0 0 1 1 1 1 50S ribosome-binding GTPase eIF2A PF08662.6 KLO17476.1 - 0.035 13.8 0.0 0.066 12.9 0.0 1.4 1 0 0 1 1 1 0 Eukaryotic translation initiation factor eIF2A B12D PF06522.6 KLO17476.1 - 0.1 12.3 0.3 1.2 8.8 0.2 2.5 1 1 0 1 1 1 0 NADH-ubiquinone reductase complex 1 MLRQ subunit DUF2561 PF10812.3 KLO17476.1 - 1.5 8.4 5.4 2.6 7.5 3.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2561) dUTPase PF00692.14 KLO17480.1 - 2.5e-40 136.9 0.0 2.9e-40 136.7 0.0 1.0 1 0 0 1 1 1 1 dUTPase p450 PF00067.17 KLO17485.1 - 3.6e-57 193.9 0.0 5.2e-57 193.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Spt4 PF06093.8 KLO17486.1 - 1.3e-29 101.8 0.4 1.6e-29 101.5 0.2 1.1 1 0 0 1 1 1 1 Spt4/RpoE2 zinc finger TAFII55_N PF04658.8 KLO17487.1 - 1e-55 187.6 1.0 2.3e-55 186.5 0.7 1.6 1 0 0 1 1 1 1 TAFII55 protein conserved region Cpn60_TCP1 PF00118.19 KLO17488.1 - 3.4e-135 451.4 9.2 3.9e-135 451.2 6.4 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family UPRTase PF14681.1 KLO17489.1 - 4.3e-77 257.9 0.0 5.3e-77 257.7 0.0 1.0 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.22 KLO17489.1 - 4.1e-05 23.2 0.0 6.5e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosyl transferase domain Cyclin_N PF00134.18 KLO17490.1 - 2e-11 43.5 1.7 9.3e-10 38.1 0.2 2.5 2 1 0 2 2 2 2 Cyclin, N-terminal domain Cyclin_C PF02984.14 KLO17490.1 - 2.1e-05 24.4 0.5 0.00094 19.1 0.1 2.6 2 0 0 2 2 2 1 Cyclin, C-terminal domain TFIIB PF00382.14 KLO17490.1 - 0.016 14.9 0.7 0.58 9.9 0.1 2.6 2 0 0 2 2 2 0 Transcription factor TFIIB repeat DUF3278 PF11683.3 KLO17490.1 - 0.072 13.0 0.2 0.22 11.5 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3278) TP2 PF01254.13 KLO17490.1 - 2.4 8.4 12.8 0.18 12.1 3.1 2.2 2 0 0 2 2 2 0 Nuclear transition protein 2 p450 PF00067.17 KLO17491.1 - 4.7e-54 183.6 0.0 7e-54 183.0 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 Peptidase_S28 PF05577.7 KLO17492.1 - 1.2e-47 162.5 2.9 2.9e-47 161.2 2.0 1.6 1 1 0 1 1 1 1 Serine carboxypeptidase S28 Peptidase_S9 PF00326.16 KLO17492.1 - 1.8e-05 24.0 0.1 7.1e-05 22.1 0.0 1.9 2 0 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_1 PF00561.15 KLO17492.1 - 0.00021 20.9 0.0 0.00036 20.1 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 KLO17492.1 - 0.00088 19.2 0.0 0.0014 18.5 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF2920 PF11144.3 KLO17492.1 - 0.0079 15.2 0.0 0.013 14.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2920) Abhydrolase_3 PF07859.8 KLO17492.1 - 0.061 12.8 0.0 0.11 11.9 0.0 1.5 1 0 0 1 1 1 0 alpha/beta hydrolase fold Esterase PF00756.15 KLO17492.1 - 0.073 12.4 0.0 0.15 11.4 0.0 1.5 1 0 0 1 1 1 0 Putative esterase Peptidase_S15 PF02129.13 KLO17492.1 - 0.16 11.3 0.0 0.32 10.3 0.0 1.4 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) DUF2638 PF10937.3 KLO17493.1 - 2e-11 44.8 3.6 4.6e-10 40.5 2.5 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF2638) Proteasome PF00227.21 KLO17494.1 - 6.1e-46 156.1 0.0 1.5e-45 154.8 0.0 1.6 1 1 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 KLO17494.1 - 2e-15 55.7 0.4 5.5e-15 54.3 0.2 1.8 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature RNA_pol_Rpb1_5 PF04998.12 KLO17495.1 - 1.9e-93 312.7 0.3 2.8e-93 312.1 0.2 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_1 PF04997.7 KLO17495.1 - 2.1e-88 296.8 0.0 3.2e-88 296.2 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_2 PF00623.15 KLO17495.1 - 2.3e-67 226.0 0.0 4.7e-67 225.0 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.13 KLO17495.1 - 1.5e-39 135.2 0.0 4.7e-39 133.6 0.0 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.12 KLO17495.1 - 6.3e-32 109.5 0.0 1.6e-31 108.2 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 Zn_Tnp_IS1 PF03811.8 KLO17495.1 - 0.034 13.6 0.0 0.084 12.3 0.0 1.7 1 0 0 1 1 1 0 InsA N-terminal domain DUF2786 PF10979.3 KLO17495.1 - 0.059 13.0 0.0 0.14 11.9 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2786) Spo7 PF03907.8 KLO17496.1 - 0.049 13.2 0.6 0.088 12.4 0.4 1.4 1 0 0 1 1 1 0 Spo7-like protein G_glu_transpept PF01019.16 KLO17497.1 - 2e-160 534.6 0.0 2.3e-160 534.4 0.0 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase Fmp27_WPPW PF10359.4 KLO17498.1 - 0.0037 15.7 10.9 0.0052 15.2 7.5 1.2 1 0 0 1 1 1 1 RNA pol II promoter Fmp27 protein domain APG6 PF04111.7 KLO17498.1 - 0.011 14.7 14.2 0.016 14.2 9.9 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 Rootletin PF15035.1 KLO17498.1 - 0.055 13.4 15.9 0.11 12.4 11.1 1.5 1 1 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion AATF-Che1 PF13339.1 KLO17498.1 - 0.14 12.2 12.8 0.03 14.4 5.5 2.3 2 0 0 2 2 2 0 Apoptosis antagonizing transcription factor DUF763 PF05559.6 KLO17498.1 - 0.17 10.7 6.2 0.71 8.7 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF763) Herpes_BLRF2 PF05812.7 KLO17498.1 - 0.23 11.2 9.5 0.22 11.3 2.8 2.8 1 1 1 2 2 2 0 Herpesvirus BLRF2 protein KLRAQ PF10205.4 KLO17498.1 - 0.29 11.1 9.3 0.82 9.7 6.5 1.8 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein V_ATPase_I PF01496.14 KLO17498.1 - 0.42 8.4 5.2 0.54 8.0 3.6 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF87 PF01935.12 KLO17498.1 - 0.45 10.2 2.4 0.8 9.4 1.7 1.3 1 0 0 1 1 1 0 Domain of unknown function DUF87 Mnd1 PF03962.10 KLO17498.1 - 0.69 9.5 12.9 1.4 8.5 9.0 1.5 1 0 0 1 1 1 0 Mnd1 family DUF972 PF06156.8 KLO17498.1 - 1 9.7 12.3 0.54 10.6 4.1 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF972) DUF4407 PF14362.1 KLO17498.1 - 1.5 7.7 10.2 2.3 7.0 7.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) HALZ PF02183.13 KLO17498.1 - 1.7 8.4 10.4 4 7.2 1.0 2.5 2 0 0 2 2 2 0 Homeobox associated leucine zipper DUF2894 PF11445.3 KLO17498.1 - 6 7.0 12.5 7.4 6.7 8.1 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2894) DUF4337 PF14235.1 KLO17498.1 - 6.5 6.5 9.0 15 5.4 6.2 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) GDI PF00996.13 KLO17500.1 - 5.7e-55 186.3 0.0 7e-55 186.0 0.0 1.1 1 0 0 1 1 1 1 GDP dissociation inhibitor Med13_C PF06333.7 KLO17501.1 - 5.5e-18 64.7 0.1 1.4e-17 63.3 0.0 1.7 1 0 0 1 1 1 1 Mediator complex subunit 13 C-terminal DUF2433 PF10360.4 KLO17502.1 - 1.7e-31 109.2 0.0 3.1e-31 108.4 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2433) RRM_6 PF14259.1 KLO17502.1 - 9.8e-07 28.6 0.0 2e-06 27.6 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 KLO17502.1 - 0.00065 19.2 0.1 0.0013 18.2 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF2478 PF10649.4 KLO17502.1 - 0.038 13.3 0.1 2.4 7.4 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2478) RRM_1 PF00076.17 KLO17504.1 - 1.3e-46 156.0 0.0 6.2e-24 83.4 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KLO17504.1 - 3e-32 110.3 0.0 3.8e-17 62.0 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KLO17504.1 - 2e-19 69.1 0.0 1.1e-09 38.0 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 KLO17504.1 - 0.00054 19.6 0.0 0.4 10.4 0.0 2.3 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.6 KLO17504.1 - 0.048 13.5 0.0 0.19 11.5 0.0 2.0 2 0 0 2 2 2 0 RNA binding motif ATP-synt_S1 PF05827.7 KLO17505.1 - 7e-12 45.2 4.1 3.6e-09 36.3 0.6 2.1 1 1 1 2 2 2 2 Vacuolar ATP synthase subunit S1 (ATP6S1) DUF898 PF05987.8 KLO17505.1 - 0.069 12.0 0.0 0.088 11.6 0.0 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF898) TMF_DNA_bd PF12329.3 KLO17506.1 - 0.013 15.2 10.9 1 9.2 3.2 3.0 3 0 0 3 3 3 0 TATA element modulatory factor 1 DNA binding Transcrip_act PF04949.8 KLO17506.1 - 0.43 10.2 5.5 0.59 9.7 0.1 2.8 2 1 1 3 3 3 0 Transcriptional activator DUF4094 PF13334.1 KLO17506.1 - 0.53 10.7 3.3 2.5 8.5 0.6 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4094) Prefoldin PF02996.12 KLO17506.1 - 0.53 9.9 4.7 3.2 7.4 0.2 2.7 3 0 0 3 3 3 0 Prefoldin subunit DivIVA PF05103.8 KLO17506.1 - 0.81 9.7 5.7 2 8.4 0.1 2.5 2 0 0 2 2 2 0 DivIVA protein bZIP_1 PF00170.16 KLO17506.1 - 1.1 9.2 10.0 1.7 8.6 0.1 3.2 3 1 0 3 3 3 0 bZIP transcription factor DUF972 PF06156.8 KLO17506.1 - 2 8.8 8.1 4.5 7.6 0.1 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF972) Spc7 PF08317.6 KLO17506.1 - 2.3 6.8 11.1 16 3.9 5.1 2.7 2 1 0 2 2 2 0 Spc7 kinetochore protein GAS PF13851.1 KLO17506.1 - 3 7.0 9.7 6.5 5.8 0.1 2.4 2 1 0 2 2 2 0 Growth-arrest specific micro-tubule binding HALZ PF02183.13 KLO17506.1 - 4.2 7.1 8.0 0.71 9.6 1.3 2.8 2 1 1 3 3 3 0 Homeobox associated leucine zipper DivIC PF04977.10 KLO17506.1 - 5.5 6.5 14.6 0.8 9.2 0.4 3.4 3 1 1 4 4 4 0 Septum formation initiator DUF4140 PF13600.1 KLO17506.1 - 7.2 7.1 11.2 4.1 7.9 0.1 3.5 2 1 1 3 3 3 0 N-terminal domain of unknown function (DUF4140) Atg14 PF10186.4 KLO17506.1 - 7.8 5.3 11.8 10 4.9 4.4 2.2 2 0 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 Actin PF00022.14 KLO17508.1 - 1.4e-155 517.6 0.0 1.5e-155 517.4 0.0 1.0 1 0 0 1 1 1 1 Actin ESSS PF10183.4 KLO17508.1 - 0.048 14.0 0.0 0.11 12.8 0.0 1.7 2 0 0 2 2 2 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) CGI-121 PF08617.5 KLO17509.1 - 8.6e-42 142.5 1.7 9.8e-42 142.3 1.2 1.0 1 0 0 1 1 1 1 Kinase binding protein CGI-121 Virul_Fac PF10139.4 KLO17509.1 - 0.0013 16.8 0.3 0.0014 16.6 0.2 1.0 1 0 0 1 1 1 1 Putative bacterial virulence factor Thioredoxin PF00085.15 KLO17510.1 - 3.9e-53 177.5 0.1 1.7e-26 91.9 0.0 3.6 4 0 0 4 4 4 2 Thioredoxin Thioredoxin_6 PF13848.1 KLO17510.1 - 2.9e-20 72.8 0.0 2.7e-10 40.3 0.0 3.9 2 1 2 4 4 4 2 Thioredoxin-like domain Thioredoxin_2 PF13098.1 KLO17510.1 - 5.5e-08 32.9 1.5 0.0041 17.2 0.0 4.1 4 2 0 4 4 4 2 Thioredoxin-like domain Thioredoxin_8 PF13905.1 KLO17510.1 - 1.6e-07 31.3 0.0 0.061 13.4 0.0 3.7 3 0 0 3 3 3 2 Thioredoxin-like Thioredoxin_4 PF13462.1 KLO17510.1 - 0.00031 20.7 1.7 0.0082 16.1 0.1 2.9 2 1 1 3 3 3 1 Thioredoxin Thioredoxin_3 PF13192.1 KLO17510.1 - 0.0015 18.3 0.0 0.49 10.2 0.0 2.8 2 0 0 2 2 2 1 Thioredoxin domain Thioredoxin_7 PF13899.1 KLO17510.1 - 0.0034 17.3 0.1 0.055 13.4 0.0 2.7 2 0 0 2 2 2 1 Thioredoxin-like Terminase_GpA PF05876.7 KLO17510.1 - 0.0091 14.4 0.9 0.092 11.0 0.1 2.1 2 0 0 2 2 2 1 Phage terminase large subunit (GpA) PPR_2 PF13041.1 KLO17511.1 - 1.4e-56 188.2 7.4 2.8e-14 52.8 0.1 14.5 10 3 3 14 14 14 10 PPR repeat family PPR PF01535.15 KLO17511.1 - 6.1e-41 135.5 11.9 3.5e-06 26.6 0.0 14.9 16 0 0 16 16 16 7 PPR repeat PPR_3 PF13812.1 KLO17511.1 - 3.6e-38 126.6 16.3 8e-05 22.6 0.0 15.9 17 1 1 18 18 18 6 Pentatricopeptide repeat domain PPR_1 PF12854.2 KLO17511.1 - 1.1e-29 101.5 0.4 1.2e-05 24.7 0.0 12.2 14 0 0 14 14 14 5 PPR repeat TPR_14 PF13428.1 KLO17511.1 - 2e-10 40.3 11.8 9.1 7.2 0.0 12.5 13 2 2 15 15 15 2 Tetratricopeptide repeat TPR_16 PF13432.1 KLO17511.1 - 4.3e-06 27.2 8.7 2.1 9.1 0.0 7.9 8 0 0 8 8 8 1 Tetratricopeptide repeat RPM2 PF08579.6 KLO17511.1 - 0.027 14.6 0.2 5.6 7.1 0.0 3.8 4 0 0 4 4 4 0 Mitochondrial ribonuclease P subunit (RPM2) Med10 PF09748.4 KLO17512.1 - 4.2e-18 65.3 0.0 6e-18 64.8 0.0 1.2 1 0 0 1 1 1 1 Transcription factor subunit Med10 of Mediator complex PIN_4 PF13638.1 KLO17512.1 - 0.015 15.3 0.0 0.018 15.1 0.0 1.2 1 0 0 1 1 1 0 PIN domain KIAA1430 PF13879.1 KLO17512.1 - 0.052 13.9 0.2 0.081 13.3 0.2 1.4 1 1 0 1 1 1 0 KIAA1430 homologue Oxidored_FMN PF00724.15 KLO17513.1 - 1.4e-90 303.7 0.0 1.6e-90 303.5 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family FA_desaturase PF00487.19 KLO17514.1 - 1.7e-14 53.9 25.7 2.9e-14 53.1 17.8 1.3 1 0 0 1 1 1 1 Fatty acid desaturase Cyt-b5 PF00173.23 KLO17514.1 - 3.9e-14 52.1 0.0 7.3e-14 51.3 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Chitin_synth_2 PF03142.10 KLO17514.1 - 0.051 11.9 0.1 0.074 11.4 0.1 1.1 1 0 0 1 1 1 0 Chitin synthase CMAS PF02353.15 KLO17515.1 - 3e-57 193.7 0.0 4e-57 193.3 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_23 PF13489.1 KLO17515.1 - 3e-08 33.5 0.0 5.1e-08 32.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KLO17515.1 - 3.8e-08 33.9 0.0 9.3e-08 32.6 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KLO17515.1 - 4.3e-06 27.1 0.0 9.7e-06 25.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KLO17515.1 - 0.00024 21.1 0.0 0.00049 20.1 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KLO17515.1 - 0.00067 19.2 0.0 0.0012 18.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KLO17515.1 - 0.0023 17.3 0.0 0.004 16.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain SAC3 PF12209.3 KLO17515.1 - 0.011 15.8 0.0 0.033 14.3 0.0 1.8 1 0 0 1 1 1 0 Leucine permease transcriptional regulator helical domain Methyltransf_12 PF08242.7 KLO17515.1 - 0.015 15.7 0.0 0.034 14.6 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_25 PF13649.1 KLO17515.1 - 0.063 13.6 0.0 0.15 12.4 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain DOT1 PF08123.8 KLO17515.1 - 0.071 12.4 0.0 0.13 11.5 0.0 1.5 1 0 0 1 1 1 0 Histone methylation protein DOT1 Methyltransf_24 PF13578.1 KLO17515.1 - 0.092 13.5 0.1 1.8 9.4 0.0 2.8 3 0 0 3 3 3 0 Methyltransferase domain CarboxypepD_reg PF13620.1 KLO17515.1 - 0.12 12.4 0.0 4 7.5 0.0 2.4 2 0 0 2 2 2 0 Carboxypeptidase regulatory-like domain Ank_2 PF12796.2 KLO17516.1 - 7.4e-21 74.2 0.0 3.8e-10 39.9 0.0 2.7 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 KLO17516.1 - 2.1e-19 68.2 0.0 6.2e-09 35.2 0.0 3.8 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.1 KLO17516.1 - 9e-16 57.5 0.0 1.8e-06 27.9 0.0 3.0 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.1 KLO17516.1 - 4.3e-15 55.7 0.1 1.4e-09 38.1 0.0 3.2 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 KLO17516.1 - 1.9e-13 49.2 0.2 0.00041 20.3 0.0 4.7 4 0 0 4 4 4 2 Ankyrin repeat KilA-N PF04383.8 KLO17516.1 - 0.0035 16.9 0.1 0.066 12.8 0.0 2.4 1 1 0 1 1 1 1 KilA-N domain DUF3122 PF11320.3 KLO17516.1 - 0.061 13.2 0.0 0.13 12.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3122) Acyl-CoA_dh_C PF12806.2 KLO17516.1 - 0.064 13.1 0.6 1.2 9.0 0.0 2.5 2 0 0 2 2 2 0 Acetyl-CoA dehydrogenase C-terminal like DnaG_DnaB_bind PF08278.6 KLO17516.1 - 0.081 13.1 3.2 0.1 12.8 1.0 1.9 2 0 0 2 2 2 0 DNA primase DnaG DnaB-binding DSPn PF14671.1 KLO17517.1 - 7.5e-40 136.1 0.0 4.5e-38 130.4 0.0 2.5 2 0 0 2 2 2 1 Dual specificity protein phosphatase, N-terminal half DSPc PF00782.15 KLO17517.1 - 3e-15 55.9 0.0 5.5e-15 55.1 0.0 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 KLO17517.1 - 8.7e-06 25.2 0.0 2.3e-05 23.8 0.0 1.7 2 0 0 2 2 2 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.1 KLO17517.1 - 0.00026 21.0 0.0 0.00045 20.2 0.0 1.4 1 0 0 1 1 1 1 Inositol hexakisphosphate Y_phosphatase3 PF13350.1 KLO17517.1 - 0.046 13.9 0.0 0.12 12.6 0.0 1.7 1 0 0 1 1 1 0 Tyrosine phosphatase family URO-D PF01208.12 KLO17518.1 - 4.8e-126 420.3 0.0 5.4e-126 420.1 0.0 1.0 1 0 0 1 1 1 1 Uroporphyrinogen decarboxylase (URO-D) COMPASS-Shg1 PF05205.7 KLO17519.1 - 6.2e-09 36.1 0.0 9.5e-09 35.5 0.0 1.3 1 0 0 1 1 1 1 COMPASS (Complex proteins associated with Set1p) component shg1 FAD_binding_3 PF01494.14 KLO17521.1 - 2.9e-66 223.9 0.0 3.8e-66 223.5 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 KLO17521.1 - 0.0015 18.4 0.0 0.0036 17.2 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 KLO17521.1 - 0.0043 15.9 0.2 0.1 11.5 0.0 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_7 PF13241.1 KLO17521.1 - 0.033 14.4 0.0 0.19 12.0 0.0 2.1 2 0 0 2 2 2 0 Putative NAD(P)-binding F420_oxidored PF03807.12 KLO17521.1 - 0.036 14.4 0.0 2.8 8.4 0.0 2.5 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent Thi4 PF01946.12 KLO17521.1 - 0.036 13.1 0.0 0.061 12.4 0.0 1.3 1 0 0 1 1 1 0 Thi4 family TrkA_N PF02254.13 KLO17521.1 - 0.042 13.8 0.0 0.1 12.5 0.0 1.6 1 0 0 1 1 1 0 TrkA-N domain ApbA PF02558.11 KLO17521.1 - 0.08 12.3 0.0 0.31 10.4 0.0 2.0 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA Kinesin PF00225.18 KLO17522.1 - 2e-107 358.7 0.0 4.6e-107 357.5 0.0 1.6 2 0 0 2 2 2 1 Kinesin motor domain DUF3694 PF12473.3 KLO17522.1 - 1.6e-40 138.0 0.1 4e-40 136.7 0.0 1.6 1 0 0 1 1 1 1 Kinesin protein PH PF00169.24 KLO17522.1 - 1.4e-13 50.9 0.1 3.9e-13 49.5 0.1 1.8 1 0 0 1 1 1 1 PH domain FHA PF00498.21 KLO17522.1 - 7.2e-06 26.0 0.1 4e-05 23.6 0.0 2.2 2 0 0 2 2 2 1 FHA domain KIF1B PF12423.3 KLO17522.1 - 1.4e-05 25.0 0.3 0.00018 21.4 0.1 2.6 2 0 0 2 2 2 1 Kinesin protein 1B FAD_binding_3 PF01494.14 KLO17523.1 - 3.2e-42 144.8 0.4 3.3e-33 115.2 0.0 2.2 1 1 1 2 2 2 2 FAD binding domain Acyl-CoA_dh_1 PF00441.19 KLO17523.1 - 2.3e-30 105.6 0.9 6.3e-30 104.2 0.7 1.8 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 KLO17523.1 - 4e-16 58.2 1.2 9.9e-16 56.9 0.3 2.2 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, middle domain Cyt-b5 PF00173.23 KLO17523.1 - 9.7e-13 47.7 0.0 2.5e-12 46.4 0.0 1.7 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Acyl-CoA_dh_N PF02771.11 KLO17523.1 - 1.5e-09 38.4 0.0 3.4e-09 37.2 0.0 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Thi4 PF01946.12 KLO17523.1 - 0.00026 20.1 0.0 0.00065 18.8 0.0 1.6 1 0 0 1 1 1 1 Thi4 family Pyr_redox_2 PF07992.9 KLO17523.1 - 0.00041 20.2 0.0 0.00085 19.2 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 KLO17523.1 - 0.0026 17.8 0.0 0.0088 16.1 0.0 2.0 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 KLO17523.1 - 0.0089 14.9 0.1 0.066 12.0 0.0 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KLO17523.1 - 0.059 13.3 0.0 0.18 11.8 0.0 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain TrkA_N PF02254.13 KLO17523.1 - 0.083 12.8 0.1 1.6 8.7 0.0 2.5 2 0 0 2 2 2 0 TrkA-N domain TetR_C_6 PF13977.1 KLO17523.1 - 0.084 12.9 0.2 24 4.9 0.1 2.8 2 0 0 2 2 2 0 Bacterial transcriptional repressor HI0933_like PF03486.9 KLO17523.1 - 0.087 11.2 0.0 0.14 10.6 0.0 1.3 1 0 0 1 1 1 0 HI0933-like protein DUF912 PF06024.7 KLO17524.1 - 0.0093 16.0 0.5 0.15 12.1 0.0 2.4 3 0 0 3 3 3 1 Nucleopolyhedrovirus protein of unknown function (DUF912) Herpes_gE PF02480.11 KLO17524.1 - 0.017 13.4 0.7 0.1 10.8 0.0 2.0 2 0 0 2 2 2 0 Alphaherpesvirus glycoprotein E DUF912 PF06024.7 KLO17528.1 - 0.016 15.2 0.0 0.14 12.1 0.0 2.1 2 0 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Herpes_gE PF02480.11 KLO17528.1 - 0.043 12.0 0.8 0.1 10.8 0.0 1.7 2 0 0 2 2 2 0 Alphaherpesvirus glycoprotein E Pex14_N PF04695.8 KLO17528.1 - 0.96 9.4 5.2 0.64 10.0 0.0 2.3 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region GET2 PF08690.5 KLO17530.1 - 0.18 11.0 1.5 47 3.0 0.2 2.9 3 0 0 3 3 3 0 GET complex subunit GET2 CAML PF14963.1 KLO17530.1 - 0.2 10.9 0.3 0.64 9.3 0.0 1.8 2 0 0 2 2 2 0 Calcium signal-modulating cyclophilin ligand L51_S25_CI-B8 PF05047.11 KLO17531.1 - 8.3e-06 25.4 0.1 4.1e-05 23.2 0.0 2.1 2 0 0 2 2 2 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain Methyltransf_33 PF10017.4 KLO17531.1 - 0.02 14.7 0.0 0.027 14.3 0.0 1.2 1 0 0 1 1 1 0 Histidine-specific methyltransferase, SAM-dependent YL1 PF05764.8 KLO17532.1 - 2.3e-28 99.4 22.4 2.9e-28 99.1 15.5 1.1 1 0 0 1 1 1 1 YL1 nuclear protein YL1_C PF08265.6 KLO17532.1 - 1.7e-09 37.0 0.0 2.6e-09 36.4 0.0 1.3 1 0 0 1 1 1 1 YL1 nuclear protein C-terminal domain adh_short PF00106.20 KLO17534.1 - 1.4e-14 54.3 0.4 2.5e-09 37.2 0.1 2.3 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.1 KLO17534.1 - 8.6e-09 35.5 0.0 3e-05 23.8 0.0 3.0 2 1 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KLO17534.1 - 0.0041 16.8 0.1 0.0076 15.9 0.1 1.4 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.5 KLO17534.1 - 0.11 11.6 0.0 0.16 11.0 0.0 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) MutS_V PF00488.16 KLO17535.1 - 4e-68 229.3 0.0 6.5e-68 228.6 0.0 1.3 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 KLO17535.1 - 2.9e-33 115.4 2.7 6.5e-33 114.2 1.9 1.6 1 0 0 1 1 1 1 MutS domain III MutS_IV PF05190.13 KLO17535.1 - 1.4e-07 31.6 0.3 3.9e-07 30.1 0.2 1.8 1 0 0 1 1 1 1 MutS family domain IV MutS_II PF05188.12 KLO17535.1 - 0.0041 17.1 0.0 0.014 15.4 0.0 2.0 1 0 0 1 1 1 1 MutS domain II Syntaxin PF00804.20 KLO17535.1 - 0.033 14.3 1.8 0.85 9.8 0.2 2.6 2 0 0 2 2 2 0 Syntaxin Amidase PF01425.16 KLO17536.1 - 4.7e-100 335.5 0.0 5.5e-100 335.2 0.0 1.0 1 0 0 1 1 1 1 Amidase DAO PF01266.19 KLO17537.1 - 1.5e-39 135.9 0.0 3.8e-39 134.6 0.0 1.6 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KLO17537.1 - 0.00033 20.6 0.0 0.00084 19.3 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 KLO17537.1 - 0.00059 19.7 0.0 0.00088 19.2 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 KLO17537.1 - 0.0018 17.3 0.0 0.0039 16.3 0.0 1.4 1 0 0 1 1 1 1 Thi4 family FAD_binding_3 PF01494.14 KLO17537.1 - 0.0081 15.2 0.6 0.012 14.6 0.4 1.2 1 0 0 1 1 1 1 FAD binding domain FAD_binding_2 PF00890.19 KLO17537.1 - 0.011 14.6 0.1 0.016 14.1 0.1 1.2 1 0 0 1 1 1 0 FAD binding domain Lycopene_cycl PF05834.7 KLO17537.1 - 0.021 13.7 0.1 0.037 12.9 0.0 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein K_oxygenase PF13434.1 KLO17537.1 - 0.044 12.7 0.0 0.072 11.9 0.0 1.2 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.1 KLO17537.1 - 0.06 13.1 0.1 0.16 11.7 0.0 1.6 1 1 0 1 1 1 0 FAD-NAD(P)-binding Pyr_redox_3 PF13738.1 KLO17537.1 - 0.11 12.5 0.0 0.26 11.3 0.0 1.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase SH3_1 PF00018.23 KLO17539.1 - 0.058 12.7 0.1 0.11 11.9 0.0 1.4 1 0 0 1 1 1 0 SH3 domain zf-UBR PF02207.15 KLO17541.1 - 8.6e-15 54.2 19.6 8.6e-15 54.2 13.6 3.3 3 0 0 3 3 3 1 Putative zinc finger in N-recognin (UBR box) ClpS PF02617.12 KLO17541.1 - 1.4e-11 43.9 0.0 4.1e-11 42.4 0.0 1.8 1 0 0 1 1 1 1 ATP-dependent Clp protease adaptor protein ClpS tRNA_U5-meth_tr PF05958.6 KLO17542.1 - 6.1e-18 64.6 0.0 7.7e-17 60.9 0.0 2.2 1 1 0 1 1 1 1 tRNA (Uracil-5-)-methyltransferase Methyltransf_31 PF13847.1 KLO17542.1 - 6.4e-07 29.0 0.0 1.1e-06 28.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KLO17542.1 - 1.1e-06 28.7 0.0 1.8e-06 27.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_15 PF09445.5 KLO17542.1 - 1e-05 25.1 0.0 2.3e-05 24.0 0.0 1.5 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Methyltransf_18 PF12847.2 KLO17542.1 - 4.4e-05 24.0 0.0 8.2e-05 23.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.10 KLO17542.1 - 0.00048 19.5 0.0 0.00078 18.8 0.0 1.2 1 0 0 1 1 1 1 Conserved hypothetical protein 95 MTS PF05175.9 KLO17542.1 - 0.00073 18.9 0.0 0.0011 18.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.8 KLO17542.1 - 0.012 14.8 0.0 0.018 14.1 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) TRM PF02005.11 KLO17542.1 - 0.014 14.3 0.0 0.018 13.9 0.0 1.2 1 0 0 1 1 1 0 N2,N2-dimethylguanosine tRNA methyltransferase UPF0020 PF01170.13 KLO17542.1 - 0.023 14.2 0.0 0.038 13.5 0.0 1.3 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 Methyltransf_23 PF13489.1 KLO17542.1 - 0.092 12.4 0.0 0.17 11.6 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain DUF1072 PF06380.6 KLO17543.1 - 0.34 10.5 4.4 0.26 10.9 1.6 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1072) UPF0180 PF03698.8 KLO17544.1 - 0.098 12.5 0.0 0.18 11.6 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0180) DUF1041 PF06292.12 KLO17544.1 - 0.13 12.4 0.0 0.23 11.6 0.0 1.4 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1041) Chs3p PF12271.3 KLO17549.1 - 4.1e-117 390.3 25.1 4.8e-117 390.1 17.4 1.0 1 0 0 1 1 1 1 Chitin synthase III catalytic subunit Glyco_transf_25 PF01755.12 KLO17550.1 - 0.00052 19.7 0.8 0.029 14.0 0.6 2.8 1 1 0 1 1 1 1 Glycosyltransferase family 25 (LPS biosynthesis protein) V-SNARE_C PF12352.3 KLO17552.1 - 0.064 13.3 0.7 0.13 12.3 0.5 1.4 1 0 0 1 1 1 0 Snare region anchored in the vesicle membrane C-terminus Cyclin PF08613.6 KLO17553.1 - 2.3e-20 73.5 0.2 4.5e-20 72.5 0.2 1.5 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.18 KLO17553.1 - 7.7e-10 38.4 0.1 1.3e-09 37.7 0.0 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain SPO22 PF08631.5 KLO17555.1 - 1.8e-25 89.5 6.4 3.9e-22 78.6 2.7 2.9 2 0 0 2 2 2 2 Meiosis protein SPO22/ZIP4 like ALIX_LYPXL_bnd PF13949.1 KLO17555.1 - 0.0063 15.5 0.5 0.015 14.2 0.3 1.6 1 0 0 1 1 1 1 ALIX V-shaped domain binding to HIV TPR_12 PF13424.1 KLO17555.1 - 0.024 14.5 10.4 1 9.3 0.1 5.1 4 3 0 4 4 4 0 Tetratricopeptide repeat Apc3 PF12895.2 KLO17555.1 - 0.028 14.5 4.5 0.087 12.9 0.7 3.5 3 0 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_2 PF07719.12 KLO17555.1 - 0.04 13.8 2.8 10 6.3 0.1 5.0 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_11 PF13414.1 KLO17555.1 - 1.3 8.7 10.4 1.6 8.4 0.0 4.7 6 0 0 6 6 6 0 TPR repeat TPR_7 PF13176.1 KLO17555.1 - 6.6 6.7 9.0 2.4 8.1 0.0 4.5 5 0 0 5 5 5 0 Tetratricopeptide repeat WD40 PF00400.27 KLO17556.1 - 2.1e-13 49.5 0.0 0.048 13.5 0.0 5.6 5 0 0 5 5 5 4 WD domain, G-beta repeat DUF2415 PF10313.4 KLO17556.1 - 0.0097 15.5 0.0 0.16 11.6 0.0 2.7 3 0 0 3 3 3 1 Uncharacterised protein domain (DUF2415) Coatomer_WDAD PF04053.9 KLO17556.1 - 0.13 11.0 0.0 0.52 9.0 0.0 1.8 2 0 0 2 2 2 0 Coatomer WD associated region G-alpha PF00503.15 KLO17557.1 - 1.1e-111 373.3 0.0 1.3e-111 373.0 0.0 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 KLO17557.1 - 1.7e-11 43.6 2.1 6.8e-07 28.6 0.5 2.6 2 1 0 2 2 2 2 ADP-ribosylation factor family Miro PF08477.8 KLO17557.1 - 0.00046 20.6 0.0 0.35 11.3 0.0 2.6 2 1 0 2 2 2 2 Miro-like protein Gtr1_RagA PF04670.7 KLO17557.1 - 0.0044 16.1 2.1 0.84 8.7 0.5 2.5 2 1 0 2 2 2 2 Gtr1/RagA G protein conserved region AAA_29 PF13555.1 KLO17557.1 - 0.015 14.7 0.0 0.031 13.7 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain MMR_HSR1 PF01926.18 KLO17557.1 - 0.027 14.4 0.0 0.34 10.8 0.0 2.3 1 1 0 1 1 1 0 50S ribosome-binding GTPase YkuI_C PF10388.4 KLO17557.1 - 0.047 13.3 0.0 0.12 12.0 0.0 1.7 1 0 0 1 1 1 0 EAL-domain associated signalling protein domain GTP_EFTU PF00009.22 KLO17557.1 - 0.062 12.7 0.0 1.5 8.1 0.0 2.4 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain SNF2_N PF00176.18 KLO17557.1 - 0.086 11.6 0.3 0.15 10.8 0.2 1.3 1 0 0 1 1 1 0 SNF2 family N-terminal domain DUF3617 PF12276.3 KLO17561.1 - 0.4 10.1 1.9 0.36 10.2 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3617) DUF1182 PF06681.8 KLO17565.1 - 0.08 12.1 0.0 0.14 11.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1182) Myc-LZ PF02344.10 KLO17569.1 - 0.13 11.8 1.3 0.28 10.8 0.9 1.4 1 0 0 1 1 1 0 Myc leucine zipper domain Med21 PF11221.3 KLO17573.1 - 2.9e-26 92.1 8.2 3.6e-26 91.8 5.7 1.1 1 0 0 1 1 1 1 Subunit 21 of Mediator complex DUF1192 PF06698.6 KLO17573.1 - 0.044 13.5 1.9 1.5 8.6 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) Cortex-I_coil PF09304.5 KLO17573.1 - 0.069 13.2 3.0 0.38 10.8 0.7 2.3 2 0 0 2 2 2 0 Cortexillin I, coiled coil DUF2089 PF09862.4 KLO17573.1 - 0.095 12.4 0.2 0.26 11.0 0.0 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF2089) Pox_polyA_pol_C PF12629.2 KLO17573.1 - 0.2 11.3 1.1 0.35 10.5 0.1 1.8 2 0 0 2 2 2 0 Poxvirus poly(A) polymerase C-terminal domain BRE1 PF08647.6 KLO17573.1 - 0.33 10.9 4.6 0.3 11.0 1.4 2.2 1 1 1 2 2 2 0 BRE1 E3 ubiquitin ligase LIN37 PF15306.1 KLO17573.1 - 0.34 10.8 4.0 6.5 6.7 0.3 2.2 1 1 1 2 2 2 0 LIN37 DUF904 PF06005.7 KLO17573.1 - 0.76 10.1 5.0 2.4 8.5 0.0 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF904) IFP_35_N PF07334.8 KLO17573.1 - 1.3 9.0 4.7 1.6 8.7 0.1 2.4 2 1 0 2 2 2 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus YgaB PF14182.1 KLO17573.1 - 1.7 8.9 6.3 0.54 10.5 0.5 2.3 1 1 0 2 2 2 0 YgaB-like protein Cullin PF00888.17 KLO17574.1 - 6.2e-102 342.0 7.0 6.2e-102 342.0 4.8 1.4 2 0 0 2 2 2 1 Cullin family Cullin_Nedd8 PF10557.4 KLO17574.1 - 2.5e-25 88.0 2.2 9.1e-25 86.2 1.5 2.0 1 0 0 1 1 1 1 Cullin protein neddylation domain Ada_Zn_binding PF02805.11 KLO17574.1 - 0.15 11.6 0.1 0.94 9.1 0.0 2.1 2 0 0 2 2 2 0 Metal binding domain of Ada DcuC PF03606.10 KLO17574.1 - 0.19 9.8 0.1 0.3 9.2 0.1 1.2 1 0 0 1 1 1 0 C4-dicarboxylate anaerobic carrier Ank_2 PF12796.2 KLO17575.1 - 2e-16 60.0 0.0 3.3e-16 59.4 0.0 1.3 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 KLO17575.1 - 2.1e-15 55.6 3.4 1.3e-07 31.0 0.0 3.1 3 0 0 3 3 3 3 Ankyrin repeat Ank_4 PF13637.1 KLO17575.1 - 1e-14 54.5 0.3 5.6e-08 33.0 0.0 2.8 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 KLO17575.1 - 4.6e-13 48.0 0.5 6.9e-05 22.7 0.0 3.1 3 0 0 3 3 3 3 Ankyrin repeat Ank_5 PF13857.1 KLO17575.1 - 2.3e-10 40.3 2.1 0.00022 21.3 0.0 3.1 2 1 1 3 3 3 3 Ankyrin repeats (many copies) AAA PF00004.24 KLO17576.1 - 8.6e-18 64.8 0.0 3e-16 59.8 0.0 2.7 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DUF815 PF05673.8 KLO17576.1 - 4.4e-06 25.8 0.0 2.2e-05 23.5 0.0 2.1 2 1 0 2 2 2 1 Protein of unknown function (DUF815) AAA_5 PF07728.9 KLO17576.1 - 0.00048 19.8 0.0 0.0014 18.3 0.0 1.9 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) BCS1_N PF08740.6 KLO17576.1 - 0.00084 19.0 0.1 0.00084 19.0 0.1 2.1 2 0 0 2 2 2 1 BCS1 N terminal AAA_16 PF13191.1 KLO17576.1 - 0.0011 19.0 0.7 0.0044 17.0 0.1 2.4 1 1 1 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 KLO17576.1 - 0.0013 18.8 0.0 0.0033 17.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 KLO17576.1 - 0.0053 17.5 4.5 0.02 15.7 0.0 2.7 2 1 0 2 2 2 1 AAA domain AAA_3 PF07726.6 KLO17576.1 - 0.02 14.5 0.0 0.041 13.4 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.1 KLO17576.1 - 0.022 14.5 0.0 0.21 11.3 0.0 2.3 2 0 0 2 2 2 0 Part of AAA domain RNA_helicase PF00910.17 KLO17576.1 - 0.027 14.6 0.0 0.069 13.3 0.0 1.7 1 0 0 1 1 1 0 RNA helicase AAA_23 PF13476.1 KLO17576.1 - 0.029 14.7 3.9 10 6.4 2.6 2.3 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.1 KLO17576.1 - 0.029 13.8 0.0 0.059 12.8 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_18 PF13238.1 KLO17576.1 - 0.038 14.2 3.2 0.2 11.9 0.0 2.5 2 0 0 2 2 2 0 AAA domain KaiC PF06745.8 KLO17576.1 - 0.087 11.9 2.1 0.2 10.7 0.0 2.4 3 0 0 3 3 3 0 KaiC AAA_24 PF13479.1 KLO17576.1 - 0.15 11.6 3.1 0.35 10.4 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_11 PF13086.1 KLO17576.1 - 0.22 11.0 9.3 7.5 6.0 6.4 2.2 1 1 0 1 1 1 0 AAA domain Nop25 PF09805.4 KLO17576.1 - 0.32 11.0 21.2 0.73 9.9 14.7 1.6 1 0 0 1 1 1 0 Nucleolar protein 12 (25kDa) DUF1510 PF07423.6 KLO17576.1 - 3.7 6.8 16.7 6.7 6.0 11.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Rtf2 PF04641.7 KLO17577.1 - 2.3e-73 246.5 5.3 2.9e-73 246.2 3.6 1.0 1 0 0 1 1 1 1 Rtf2 RING-finger zf-Nse PF11789.3 KLO17577.1 - 0.005 16.3 0.0 0.05 13.1 0.0 2.5 2 1 1 3 3 3 1 Zinc-finger of the MIZ type in Nse subunit DUF966 PF06136.8 KLO17577.1 - 1.2 8.4 9.1 1.8 7.8 6.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF966) FYDLN_acid PF09538.5 KLO17577.1 - 1.9 9.1 8.7 9 6.9 6.0 2.3 1 1 0 1 1 1 0 Protein of unknown function (FYDLN_acid) MRP-S31 PF15433.1 KLO17577.1 - 3 7.1 8.3 4.5 6.6 5.8 1.2 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S31 PS_Dcarbxylase PF02666.10 KLO17578.1 - 2.4e-77 258.8 0.0 7.6e-75 250.6 0.0 2.2 1 1 0 1 1 1 1 Phosphatidylserine decarboxylase ChaC PF04752.7 KLO17579.1 - 1.4e-55 188.0 0.0 1.6e-55 187.8 0.0 1.0 1 0 0 1 1 1 1 ChaC-like protein Urotensin_II PF02083.10 KLO17583.1 - 1.5 8.2 5.7 2.8 7.4 4.0 1.4 1 0 0 1 1 1 0 Urotensin II DUF2269 PF10027.4 KLO17584.1 - 6.4 6.5 12.8 2.6 7.8 5.4 2.3 1 1 1 2 2 2 0 Predicted integral membrane protein (DUF2269) DUF3752 PF12572.3 KLO17585.1 - 2.1e-34 118.8 6.2 2.1e-34 118.8 4.3 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF3752) Cas_Csy4 PF09618.5 KLO17585.1 - 2.7 7.7 4.8 4.7 6.9 3.4 1.3 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Csy4) Sox_N PF12444.3 KLO17588.1 - 0.029 15.4 1.3 0.043 14.9 0.3 1.7 2 0 0 2 2 2 0 Sox developmental protein N terminal DUF4200 PF13863.1 KLO17588.1 - 0.076 12.9 3.3 0.12 12.2 2.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) Vps35 PF03635.12 KLO17589.1 - 0 1050.7 1.7 0 1050.5 1.2 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 35 Ribonuc_L-PSP PF01042.16 KLO17589.1 - 0.045 13.4 0.0 0.15 11.8 0.0 1.8 1 0 0 1 1 1 0 Endoribonuclease L-PSP UbiA PF01040.13 KLO17590.1 - 5.5e-26 91.3 7.9 8.5e-26 90.7 5.5 1.2 1 0 0 1 1 1 1 UbiA prenyltransferase family DUF21 PF01595.15 KLO17591.1 - 1e-29 103.1 0.1 1.7e-29 102.4 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function DUF21 CBS PF00571.23 KLO17591.1 - 1e-05 25.2 0.3 0.38 10.5 0.0 3.5 3 0 0 3 3 3 2 CBS domain p450 PF00067.17 KLO17594.1 - 5.2e-73 246.1 0.0 5.9e-73 245.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 UbiA PF01040.13 KLO17595.1 - 1e-26 93.7 11.4 1.4e-26 93.2 7.9 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family DUF3329 PF11808.3 KLO17595.1 - 4.4 7.4 6.4 0.38 10.8 0.7 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3329) CFEM PF05730.6 KLO17597.1 - 4.5e-09 35.9 13.6 7.1e-09 35.3 9.5 1.3 1 0 0 1 1 1 1 CFEM domain zf-MYND PF01753.13 KLO17598.1 - 1.5e-07 31.1 11.3 1.5e-07 31.1 7.8 2.3 3 0 0 3 3 3 1 MYND finger EPSP_synthase PF00275.15 KLO17598.1 - 0.17 10.3 0.1 0.28 9.5 0.1 1.2 1 0 0 1 1 1 0 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) DUF2318 PF10080.4 KLO17598.1 - 0.3 10.8 2.6 0.75 9.5 1.8 1.6 1 0 0 1 1 1 0 Predicted membrane protein (DUF2318) E7 PF00527.13 KLO17602.1 - 0.059 13.5 0.0 0.12 12.5 0.0 1.6 1 0 0 1 1 1 0 E7 protein, Early protein EcKinase PF02958.15 KLO17603.1 - 0.17 10.9 0.0 0.24 10.4 0.0 1.2 1 0 0 1 1 1 0 Ecdysteroid kinase VHS PF00790.14 KLO17605.1 - 3.7e-44 149.7 0.4 2.9e-42 143.6 0.0 2.6 2 0 0 2 2 2 1 VHS domain FYVE PF01363.16 KLO17605.1 - 2.3e-17 62.6 7.3 3.9e-17 61.9 5.1 1.3 1 0 0 1 1 1 1 FYVE zinc finger FYVE_2 PF02318.11 KLO17605.1 - 0.0014 18.4 3.9 0.0029 17.4 2.7 1.4 1 0 0 1 1 1 1 FYVE-type zinc finger UIM PF02809.15 KLO17605.1 - 0.0024 17.2 13.4 0.02 14.4 2.2 3.4 3 0 0 3 3 3 2 Ubiquitin interaction motif DZR PF12773.2 KLO17605.1 - 0.056 13.2 7.7 1.5 8.6 2.7 2.4 1 1 1 2 2 2 0 Double zinc ribbon zf-DHHC PF01529.15 KLO17605.1 - 0.078 12.3 1.2 0.19 11.0 0.8 1.6 1 0 0 1 1 1 0 DHHC palmitoyltransferase Prok-RING_1 PF14446.1 KLO17605.1 - 3.4 7.4 7.6 19 5.0 0.2 2.3 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 zinc-ribbons_6 PF07191.7 KLO17605.1 - 4.3 7.2 7.8 32 4.3 5.4 2.1 1 1 0 1 1 1 0 zinc-ribbons zf-MYND PF01753.13 KLO17608.1 - 1.6e-08 34.2 11.8 2.6e-08 33.6 8.2 1.3 1 0 0 1 1 1 1 MYND finger ATP11 PF06644.6 KLO17609.1 - 2.8e-63 213.9 0.0 3.5e-63 213.5 0.0 1.0 1 0 0 1 1 1 1 ATP11 protein tRNA-synt_1c PF00749.16 KLO17610.1 - 2.1e-85 286.1 0.0 3.6e-85 285.4 0.0 1.4 1 1 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain HR1 PF02185.11 KLO17611.1 - 0.12 12.1 0.0 0.15 11.7 0.0 1.3 1 1 0 1 1 1 0 Hr1 repeat TRAPP PF04051.11 KLO17612.1 - 4.2e-32 110.7 0.0 5.7e-32 110.3 0.0 1.2 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component Telomere_Sde2_2 PF13297.1 KLO17612.1 - 0.19 11.0 1.6 0.7 9.2 0.1 2.2 2 0 0 2 2 2 0 Telomere stability C-terminal zf-Apc11 PF12861.2 KLO17613.1 - 1.2e-39 134.0 9.7 1.4e-39 133.7 6.7 1.1 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.2 KLO17613.1 - 4.7e-31 106.7 10.3 6.1e-31 106.3 7.1 1.1 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_2 PF13639.1 KLO17613.1 - 3.1e-05 23.6 17.0 0.00013 21.7 11.8 2.1 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 KLO17613.1 - 0.035 14.1 10.5 0.13 12.2 7.3 1.9 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KLO17613.1 - 0.11 12.1 14.7 0.49 10.1 10.2 2.1 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-Nse PF11789.3 KLO17613.1 - 0.2 11.2 5.4 0.36 10.3 3.8 1.4 1 1 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-RING_5 PF14634.1 KLO17613.1 - 0.22 11.2 13.8 2.8 7.7 10.0 2.3 1 1 1 2 2 2 0 zinc-RING finger domain zf-RING_UBOX PF13445.1 KLO17613.1 - 1.7 8.4 7.9 3.8 7.3 5.5 1.7 1 1 0 1 1 1 0 RING-type zinc-finger PSP1 PF04468.7 KLO17614.1 - 7.1e-35 118.8 2.6 1.8e-34 117.5 1.8 1.7 1 0 0 1 1 1 1 PSP1 C-terminal conserved region Rgp1 PF08737.5 KLO17615.1 - 2.7e-53 181.5 0.2 6.1e-53 180.3 0.2 1.5 1 1 0 1 1 1 1 Rgp1 Arrestin_C PF02752.17 KLO17615.1 - 9.2e-07 29.0 0.1 0.039 14.0 0.0 3.8 3 1 1 4 4 4 2 Arrestin (or S-antigen), C-terminal domain zf-MYND PF01753.13 KLO17616.1 - 4.1e-09 36.1 9.8 7.6e-09 35.3 6.8 1.5 1 0 0 1 1 1 1 MYND finger zf-MYND PF01753.13 KLO17617.1 - 1.9e-09 37.2 9.2 3e-09 36.5 6.4 1.3 1 0 0 1 1 1 1 MYND finger A2L_zn_ribbon PF08792.5 KLO17617.1 - 0.16 11.4 0.0 0.16 11.4 0.0 1.9 2 0 0 2 2 2 0 A2L zinc ribbon domain zf-HIT PF04438.11 KLO17617.1 - 1.4 8.6 7.7 3.2 7.4 5.4 1.6 1 1 0 1 1 1 0 HIT zinc finger zf-MYND PF01753.13 KLO17618.1 - 1.2e-09 37.8 11.1 2e-09 37.1 7.7 1.4 1 0 0 1 1 1 1 MYND finger PCI PF01399.22 KLO17619.1 - 1.8e-07 31.4 2.4 2.3e-07 31.0 0.4 2.0 2 0 0 2 2 2 1 PCI domain RQC PF09382.5 KLO17619.1 - 0.042 13.5 0.0 0.093 12.4 0.0 1.6 1 0 0 1 1 1 0 RQC domain DUF572 PF04502.8 KLO17619.1 - 0.11 11.6 1.6 0.14 11.3 1.1 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) Jnk-SapK_ap_N PF09744.4 KLO17619.1 - 0.16 11.9 1.9 0.26 11.2 1.3 1.2 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 TIP120 PF08623.5 KLO17620.1 - 4.6e-52 176.0 0.4 4.6e-52 176.0 0.3 2.5 3 0 0 3 3 3 1 TATA-binding protein interacting (TIP20) HEAT_2 PF13646.1 KLO17620.1 - 1.1e-17 64.0 16.6 0.006 16.8 1.0 8.7 7 2 2 9 9 9 5 HEAT repeats HEAT_EZ PF13513.1 KLO17620.1 - 1.1e-09 38.4 40.5 0.15 12.6 0.1 12.4 9 2 5 14 14 12 5 HEAT-like repeat Adaptin_N PF01602.15 KLO17620.1 - 2.6e-09 35.9 8.1 3.3e-05 22.4 0.0 4.8 4 2 0 4 4 4 2 Adaptin N terminal region UME PF08064.8 KLO17620.1 - 9.3e-09 35.2 0.0 0.064 13.2 0.0 4.8 4 0 0 4 4 4 2 UME (NUC010) domain Cnd1 PF12717.2 KLO17620.1 - 1.6e-08 34.6 4.0 0.046 13.5 0.1 5.7 4 2 2 6 6 5 3 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.17 KLO17620.1 - 1.1e-07 31.2 37.6 0.0018 18.1 0.0 12.5 15 0 0 15 15 12 2 HEAT repeat Vac14_Fab1_bd PF12755.2 KLO17620.1 - 5.6e-07 29.8 1.6 14 6.1 0.0 7.3 7 1 1 8 8 8 0 Vacuolar 14 Fab1-binding region CLASP_N PF12348.3 KLO17620.1 - 7e-06 25.5 0.2 0.82 8.9 0.0 4.6 3 2 0 3 3 3 2 CLASP N terminal DUF1546 PF07571.8 KLO17620.1 - 3.6e-05 23.7 0.2 0.64 10.1 0.0 4.1 4 0 0 4 4 4 2 Protein of unknown function (DUF1546) DUF4042 PF13251.1 KLO17620.1 - 0.00019 20.9 4.7 3.2 7.1 0.0 6.3 6 1 0 6 6 6 1 Domain of unknown function (DUF4042) Ipi1_N PF12333.3 KLO17620.1 - 0.00051 19.9 0.8 6.3 6.8 0.0 5.7 6 0 0 6 6 5 1 Rix1 complex component involved in 60S ribosome maturation Sec7_N PF12783.2 KLO17620.1 - 0.051 12.9 0.3 2.8 7.3 0.0 2.9 2 0 0 2 2 2 0 Guanine nucleotide exchange factor in Golgi transport N-terminal MMS19_N PF14500.1 KLO17620.1 - 0.061 12.5 0.4 27 3.9 0.0 4.1 4 0 0 4 4 4 0 Dos2-interacting transcription regulator of RNA-Pol-II RGS-like PF09128.6 KLO17620.1 - 0.094 12.2 0.2 0.2 11.1 0.1 1.4 1 0 0 1 1 1 0 Regulator of G protein signalling-like domain Nucleoplasmin PF03066.10 KLO17620.1 - 0.27 10.7 2.2 0.55 9.7 1.5 1.4 1 0 0 1 1 1 0 Nucleoplasmin Pro_dh PF01619.13 KLO17621.1 - 9.9e-38 129.8 0.0 1.2e-36 126.3 0.0 2.3 1 1 0 1 1 1 1 Proline dehydrogenase AAA_16 PF13191.1 KLO17622.1 - 0.0019 18.2 0.0 0.0083 16.1 0.0 1.9 1 1 0 1 1 1 1 AAA ATPase domain Transmemb_17 PF09799.4 KLO17622.1 - 0.13 12.5 0.0 0.63 10.3 0.0 2.0 2 0 0 2 2 2 0 Predicted membrane protein Acetyltransf_1 PF00583.19 KLO17623.1 - 2.9e-06 27.2 0.0 5.2e-06 26.4 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_3 PF13302.1 KLO17623.1 - 1e-05 25.7 0.0 1.7e-05 24.9 0.0 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 KLO17623.1 - 0.00014 21.5 0.0 0.00031 20.4 0.0 1.5 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_4 PF13420.1 KLO17623.1 - 0.0004 20.3 0.0 0.00066 19.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 KLO17623.1 - 0.0078 16.0 0.0 0.017 15.0 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 KLO17623.1 - 0.01 15.9 0.1 0.04 14.0 0.0 1.9 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain zf-CCCH_2 PF14608.1 KLO17624.1 - 4.9e-10 39.0 31.8 0.0011 18.8 3.4 4.8 4 1 0 4 4 4 4 Zinc finger C-x8-C-x5-C-x3-H type OHA PF14418.1 KLO17624.1 - 0.014 14.9 0.1 0.029 13.8 0.1 1.4 1 0 0 1 1 1 0 OST-HTH Associated domain Lambda_CIII PF02061.11 KLO17625.1 - 0.12 12.3 0.2 0.33 10.9 0.1 1.8 2 0 0 2 2 2 0 Lambda Phage CIII AA_permease_2 PF13520.1 KLO17626.1 - 4.1e-69 233.1 41.0 5e-69 232.8 28.4 1.1 1 0 0 1 1 1 1 Amino acid permease F-box-like PF12937.2 KLO17627.1 - 0.018 14.7 0.4 0.039 13.6 0.3 1.5 1 0 0 1 1 1 0 F-box-like FTH PF01827.22 KLO17628.1 - 0.0014 18.2 0.3 0.0034 16.9 0.2 1.6 1 0 0 1 1 1 1 FTH domain Cep57_CLD PF14073.1 KLO17628.1 - 0.03 14.1 1.1 0.054 13.3 0.8 1.3 1 0 0 1 1 1 0 Centrosome localisation domain of Cep57 F-box-like PF12937.2 KLO17629.1 - 0.043 13.5 0.0 0.088 12.5 0.0 1.5 1 0 0 1 1 1 0 F-box-like DUF1336 PF07059.7 KLO17629.1 - 0.051 12.9 0.0 2.2 7.6 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1336) CPSase_L_D2 PF02786.12 KLO17630.1 - 1.1e-107 358.0 0.0 6.9e-82 273.8 0.0 2.3 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_D3 PF02787.14 KLO17630.1 - 8.8e-40 135.2 0.1 1.8e-39 134.3 0.1 1.5 1 0 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain ATP-grasp_4 PF13535.1 KLO17630.1 - 5.2e-37 127.3 0.0 6.3e-21 74.9 0.0 2.6 2 0 0 2 2 2 2 ATP-grasp domain CPSase_L_chain PF00289.17 KLO17630.1 - 4.2e-35 120.1 0.0 4.4e-18 65.3 0.0 2.6 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, N-terminal domain ATPgrasp_Ter PF15632.1 KLO17630.1 - 3.5e-24 85.1 0.0 1.3e-12 47.1 0.0 4.0 3 1 0 3 3 3 3 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp PF02222.17 KLO17630.1 - 7e-18 64.5 0.0 2.8e-08 33.3 0.0 2.7 3 0 0 3 3 3 2 ATP-grasp domain Dala_Dala_lig_C PF07478.8 KLO17630.1 - 4.2e-12 45.8 0.0 4.8e-05 22.8 0.0 2.5 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus RimK PF08443.6 KLO17630.1 - 1.6e-09 37.5 0.0 2.2e-05 24.0 0.0 2.5 2 0 0 2 2 2 2 RimK-like ATP-grasp domain ATP-grasp_3 PF02655.9 KLO17630.1 - 2.4e-06 27.5 0.0 0.0025 17.7 0.0 2.6 2 0 0 2 2 2 2 ATP-grasp domain ATP-grasp_5 PF13549.1 KLO17630.1 - 2.6e-06 26.8 0.0 0.015 14.5 0.0 2.5 2 0 0 2 2 2 2 ATP-grasp domain GARS_A PF01071.14 KLO17630.1 - 0.089 12.3 0.0 3.5 7.1 0.0 2.3 2 0 0 2 2 2 0 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain Sdh_cyt PF01127.17 KLO17631.1 - 1.9e-25 89.0 1.3 2.5e-25 88.6 0.9 1.1 1 0 0 1 1 1 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit Lyase_aromatic PF00221.14 KLO17632.1 - 5.2e-152 506.5 0.5 6.9e-152 506.1 0.3 1.1 1 0 0 1 1 1 1 Aromatic amino acid lyase Fcf1 PF04900.7 KLO17633.1 - 3e-39 133.1 1.6 3.7e-39 132.8 0.2 1.7 2 0 0 2 2 2 1 Fcf1 ARF7EP_C PF14949.1 KLO17633.1 - 7.3 7.0 7.7 63 4.0 5.3 2.2 1 1 0 1 1 1 0 ARF7 effector protein C-terminus DAO PF01266.19 KLO17635.1 - 4.3e-42 144.2 0.0 1.9e-41 142.2 0.0 1.8 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 KLO17635.1 - 3.2e-05 23.9 0.0 0.026 14.3 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 KLO17635.1 - 0.00024 20.8 0.0 0.46 10.2 0.0 2.4 2 0 0 2 2 2 2 FAD-NAD(P)-binding Amino_oxidase PF01593.19 KLO17635.1 - 0.0037 16.3 0.0 0.0058 15.7 0.0 1.4 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase GIDA PF01134.17 KLO17635.1 - 0.01 14.7 0.2 0.022 13.6 0.0 1.6 2 0 0 2 2 2 0 Glucose inhibited division protein A FAD_binding_2 PF00890.19 KLO17635.1 - 0.01 14.7 0.0 0.064 12.0 0.0 2.0 2 0 0 2 2 2 0 FAD binding domain Pyr_redox_3 PF13738.1 KLO17635.1 - 0.025 14.6 0.0 9.6 6.2 0.0 2.6 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KLO17635.1 - 0.044 13.7 0.0 0.12 12.3 0.0 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.14 KLO17637.1 - 2.5e-19 69.5 0.0 5e-19 68.5 0.0 1.5 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 KLO17637.1 - 1.8e-10 40.3 1.0 7.9e-06 25.0 0.5 2.3 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KLO17637.1 - 9e-06 25.6 0.1 2.4e-05 24.2 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.19 KLO17637.1 - 3.3e-05 23.1 4.3 0.00028 20.0 0.3 2.6 3 0 0 3 3 3 1 Flavin containing amine oxidoreductase Pyr_redox_2 PF07992.9 KLO17637.1 - 0.00016 21.5 0.1 0.0038 17.1 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 KLO17637.1 - 0.00086 18.2 0.4 0.0015 17.4 0.2 1.3 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.9 KLO17637.1 - 0.0076 14.7 0.2 0.51 8.7 0.1 2.1 2 0 0 2 2 2 1 HI0933-like protein FAD_oxidored PF12831.2 KLO17637.1 - 0.014 14.4 2.3 0.09 11.8 1.6 2.1 1 1 0 1 1 1 0 FAD dependent oxidoreductase GIDA PF01134.17 KLO17637.1 - 0.019 13.8 0.3 0.53 9.0 0.1 2.0 2 0 0 2 2 2 0 Glucose inhibited division protein A Lycopene_cycl PF05834.7 KLO17637.1 - 0.085 11.7 0.3 1.6 7.5 0.0 2.2 2 0 0 2 2 2 0 Lycopene cyclase protein Trp_halogenase PF04820.9 KLO17637.1 - 0.14 10.7 3.1 0.89 8.0 0.0 2.7 3 0 0 3 3 3 0 Tryptophan halogenase Pyr_redox PF00070.22 KLO17637.1 - 0.28 11.6 1.9 1.2 9.6 0.8 2.3 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DSPc PF00782.15 KLO17639.1 - 3.7e-05 23.3 0.0 7.7e-05 22.2 0.0 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.1 KLO17639.1 - 0.014 15.6 0.0 0.041 14.1 0.0 1.7 1 0 0 1 1 1 0 Tyrosine phosphatase family Y_phosphatase PF00102.22 KLO17639.1 - 0.068 12.4 0.0 0.15 11.3 0.0 1.4 1 0 0 1 1 1 0 Protein-tyrosine phosphatase Cyclin_N PF00134.18 KLO17640.1 - 2.3e-42 143.5 0.5 4e-41 139.5 0.6 2.2 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 KLO17640.1 - 2.6e-24 85.4 0.3 3.1e-23 81.9 0.0 2.6 2 0 0 2 2 2 1 Cyclin, C-terminal domain tRNA-synt_1 PF00133.17 KLO17641.1 - 4.2e-151 503.9 0.0 5.4e-151 503.5 0.0 1.0 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.8 KLO17641.1 - 2e-26 92.5 0.1 3.7e-26 91.7 0.1 1.4 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.6 KLO17641.1 - 8.9e-25 87.1 0.1 8.2e-15 54.3 0.0 3.4 3 0 0 3 3 3 3 tRNA synthetases class I (M) zf-FPG_IleRS PF06827.9 KLO17641.1 - 0.00029 20.3 3.2 0.00058 19.4 2.2 1.5 1 0 0 1 1 1 1 Zinc finger found in FPG and IleRS tRNA-synt_1e PF01406.14 KLO17641.1 - 0.001 18.2 0.0 0.34 9.9 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain tRNA-synt_1b PF00579.20 KLO17641.1 - 0.039 13.0 0.1 0.066 12.3 0.0 1.3 1 0 0 1 1 1 0 tRNA synthetases class I (W and Y) ERM PF00769.14 KLO17642.1 - 0.21 11.0 29.1 0.39 10.2 20.2 1.3 1 0 0 1 1 1 0 Ezrin/radixin/moesin family ADIP PF11559.3 KLO17642.1 - 0.27 11.1 26.4 0.13 12.1 8.6 2.5 1 1 0 2 2 2 0 Afadin- and alpha -actinin-Binding DUF4200 PF13863.1 KLO17642.1 - 0.33 10.8 26.0 0.22 11.4 11.3 2.6 1 1 0 2 2 2 0 Domain of unknown function (DUF4200) NPV_P10 PF05531.7 KLO17642.1 - 1.6 9.0 6.5 43 4.4 0.1 3.4 3 0 0 3 3 3 0 Nucleopolyhedrovirus P10 protein Fib_alpha PF08702.5 KLO17642.1 - 1.8 8.6 7.8 6.5 6.8 4.6 2.3 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family Asp-B-Hydro_N PF05279.6 KLO17642.1 - 7 6.4 13.5 11 5.8 9.4 1.2 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region FAD_binding_4 PF01565.18 KLO17643.1 - 7.4e-16 57.8 0.4 8.4e-15 54.4 0.7 2.3 3 0 0 3 3 3 1 FAD binding domain BBE PF08031.7 KLO17643.1 - 5.4e-10 39.0 0.0 1e-09 38.1 0.0 1.5 1 0 0 1 1 1 1 Berberine and berberine like p450 PF00067.17 KLO17644.1 - 7.7e-65 219.1 0.0 9.2e-65 218.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 KLO17645.1 - 2.7e-60 204.2 0.0 3.2e-60 203.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 KLO17646.1 - 2.6e-61 207.5 0.0 3.5e-61 207.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 FAD_binding_4 PF01565.18 KLO17647.1 - 2.8e-15 55.9 1.9 5.6e-15 55.0 0.8 2.0 2 0 0 2 2 2 1 FAD binding domain BBE PF08031.7 KLO17647.1 - 1.1e-08 34.8 0.0 2.2e-08 33.8 0.0 1.6 1 0 0 1 1 1 1 Berberine and berberine like ProRS-C_1 PF09180.6 KLO17648.1 - 5.8e-24 83.7 1.2 1.3e-23 82.7 0.8 1.6 1 0 0 1 1 1 1 Prolyl-tRNA synthetase, C-terminal tRNA-synt_2b PF00587.20 KLO17648.1 - 1.3e-20 73.6 0.1 2.3e-20 72.9 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 KLO17648.1 - 3.2e-15 55.8 0.0 8.6e-15 54.4 0.0 1.8 2 0 0 2 2 2 1 Anticodon binding domain tRNA_edit PF04073.10 KLO17648.1 - 3.9e-07 29.9 0.1 9.6e-07 28.6 0.0 1.6 1 0 0 1 1 1 1 Aminoacyl-tRNA editing domain ADH_N PF08240.7 KLO17649.1 - 7.3e-34 115.8 1.7 1.5e-33 114.8 1.2 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KLO17649.1 - 6.1e-15 54.9 0.0 1.4e-14 53.7 0.0 1.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 KLO17649.1 - 9.5e-06 26.5 0.0 3e-05 24.9 0.0 1.7 1 1 1 2 2 2 1 Zinc-binding dehydrogenase FAD_binding_3 PF01494.14 KLO17649.1 - 3.3e-05 23.1 0.1 4.2e-05 22.7 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain Shikimate_DH PF01488.15 KLO17649.1 - 0.0086 16.1 0.1 0.018 15.1 0.0 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase DUF2338 PF10100.4 KLO17649.1 - 0.0087 14.4 0.0 0.012 13.9 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2338) Pyr_redox_2 PF07992.9 KLO17649.1 - 0.033 14.0 0.2 0.057 13.2 0.1 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Methyltransf_24 PF13578.1 KLO17649.1 - 0.1 13.4 0.0 0.19 12.5 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain TrkA_N PF02254.13 KLO17649.1 - 0.13 12.2 0.1 0.3 11.0 0.1 1.6 1 1 0 1 1 1 0 TrkA-N domain 3Beta_HSD PF01073.14 KLO17650.1 - 1.5e-27 95.9 0.0 9.3e-17 60.6 0.0 2.2 2 0 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 KLO17650.1 - 8.6e-13 48.2 0.0 2.5e-12 46.7 0.0 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 KLO17650.1 - 7.8e-12 44.6 0.0 1.6e-07 30.5 0.0 2.1 2 0 0 2 2 2 2 Male sterility protein Polysacc_synt_2 PF02719.10 KLO17650.1 - 5e-05 22.3 0.0 8.6e-05 21.5 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein KR PF08659.5 KLO17650.1 - 0.00025 20.7 0.1 0.0008 19.1 0.0 1.8 1 1 0 1 1 1 1 KR domain adh_short PF00106.20 KLO17650.1 - 0.00027 20.8 2.3 0.00059 19.8 0.5 2.2 2 1 0 2 2 2 1 short chain dehydrogenase NAD_binding_10 PF13460.1 KLO17650.1 - 0.00055 19.9 0.5 0.0087 16.0 0.3 2.5 1 1 0 1 1 1 1 NADH(P)-binding RmlD_sub_bind PF04321.12 KLO17650.1 - 0.019 13.8 0.0 0.2 10.5 0.0 2.0 2 0 0 2 2 2 0 RmlD substrate binding domain SURF4 PF02077.10 KLO17651.1 - 4.1e-94 314.8 7.6 4.7e-94 314.6 5.2 1.0 1 0 0 1 1 1 1 SURF4 family NDUF_B12 PF08122.7 KLO17651.1 - 0.27 10.9 2.5 2.3 7.9 0.3 2.8 2 0 0 2 2 2 0 NADH-ubiquinone oxidoreductase B12 subunit family Hormone_3 PF00159.13 KLO17651.1 - 0.32 11.0 0.2 0.32 11.0 0.1 1.9 2 0 0 2 2 2 0 Pancreatic hormone peptide HR_lesion PF05514.6 KLO17651.1 - 2.5 7.9 9.6 1.1 9.1 0.7 3.3 2 2 2 4 4 4 0 HR-like lesion-inducing DUF1430 PF07242.6 KLO17651.1 - 8.4 6.5 9.6 2.3 8.3 0.6 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1430) Cyt-b5 PF00173.23 KLO17652.1 - 1.8e-20 72.5 0.2 4.1e-20 71.3 0.1 1.7 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain FA_hydroxylase PF04116.8 KLO17652.1 - 6.3e-08 33.0 17.9 6.3e-08 33.0 12.4 2.0 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily Fungal_trans PF04082.13 KLO17653.1 - 3.4e-38 131.0 0.0 6e-38 130.1 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KLO17653.1 - 1.2e-07 31.5 11.2 2.2e-07 30.6 7.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain F-box-like PF12937.2 KLO17654.1 - 7.6e-09 35.1 1.1 5.7e-08 32.3 0.2 2.6 3 0 0 3 3 3 1 F-box-like F-box PF00646.28 KLO17654.1 - 0.013 15.1 0.4 0.11 12.2 0.0 2.7 3 1 0 3 3 3 0 F-box domain HLH PF00010.21 KLO17655.1 - 2.9e-12 46.0 0.0 1.2e-11 44.0 0.1 2.2 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain PRP21_like_P PF12230.3 KLO17655.1 - 0.11 11.9 1.0 0.21 11.0 0.7 1.4 1 0 0 1 1 1 0 Pre-mRNA splicing factor PRP21 like protein Prothymosin PF03247.9 KLO17655.1 - 1.5 8.9 23.4 0.54 10.4 10.4 2.6 2 0 0 2 2 2 0 Prothymosin/parathymosin family LANC_like PF05147.8 KLO17656.1 - 1.3e-06 27.2 0.0 3.1e-06 25.9 0.0 1.8 1 1 0 1 1 1 1 Lanthionine synthetase C-like protein BTB PF00651.26 KLO17657.1 - 0.014 15.3 0.0 0.053 13.5 0.0 1.9 2 0 0 2 2 2 0 BTB/POZ domain Myb_DNA-bind_3 PF12776.2 KLO17660.1 - 1.9e-12 47.6 0.6 3.6e-12 46.7 0.4 1.5 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_4 PF13837.1 KLO17660.1 - 4.8e-06 26.6 0.3 1.2e-05 25.3 0.1 1.7 1 1 0 1 1 1 1 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.4 KLO17660.1 - 0.38 10.9 2.1 0.39 10.9 0.0 2.1 3 0 0 3 3 3 0 Alcohol dehydrogenase transcription factor Myb/SANT-like NUC153 PF08159.7 KLO17661.1 - 2.7e-14 52.4 0.7 1e-13 50.6 0.5 2.0 1 0 0 1 1 1 1 NUC153 domain Tocopherol_cycl PF14249.1 KLO17662.1 - 0.00047 18.9 0.6 0.01 14.5 0.3 2.2 2 0 0 2 2 2 2 Tocopherol cyclase RRF PF01765.14 KLO17663.1 - 2.1e-26 92.3 0.1 3e-26 91.8 0.1 1.2 1 0 0 1 1 1 1 Ribosome recycling factor WD40 PF00400.27 KLO17665.1 - 9.9e-70 228.1 27.9 5.5e-13 48.2 0.2 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat Apc4_WD40 PF12894.2 KLO17665.1 - 2.2e-09 36.6 0.0 0.23 11.0 0.0 4.9 5 0 0 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Nucleoporin_N PF08801.6 KLO17665.1 - 0.0045 15.8 1.1 3.4 6.3 0.4 3.6 2 2 1 3 3 3 2 Nup133 N terminal like lci PF12197.3 KLO17665.1 - 0.057 13.0 0.0 0.15 11.6 0.0 1.7 1 0 0 1 1 1 0 Bacillus cereus group antimicrobial protein VCBS PF13517.1 KLO17665.1 - 0.64 10.4 0.0 0.64 10.4 0.0 3.3 4 0 0 4 4 4 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella APH PF01636.18 KLO17666.1 - 2.1e-09 37.4 0.2 2.3e-08 34.0 0.1 2.1 1 1 0 1 1 1 1 Phosphotransferase enzyme family UPF0147 PF03685.8 KLO17666.1 - 0.0022 17.8 0.3 0.048 13.5 0.1 2.4 2 0 0 2 2 2 1 Uncharacterised protein family (UPF0147) DUF2520 PF10728.4 KLO17667.1 - 0.015 14.7 1.7 0.48 9.8 0.1 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF2520) SNF2_N PF00176.18 KLO17670.1 - 2.9e-71 239.7 5.9 4.6e-71 239.0 4.1 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 KLO17670.1 - 3.9e-11 42.6 0.8 1.1e-10 41.1 0.1 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain zf-C3HC4_3 PF13920.1 KLO17670.1 - 5.3e-09 35.6 9.6 1e-08 34.6 6.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KLO17670.1 - 7e-09 35.5 6.1 1.6e-08 34.3 4.2 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KLO17670.1 - 1.4e-08 34.4 6.6 3.5e-08 33.1 4.6 1.7 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 KLO17670.1 - 4.7e-08 32.6 5.4 9.2e-08 31.6 3.8 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.20 KLO17670.1 - 8.1e-08 31.8 6.3 1.8e-07 30.7 4.4 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 KLO17670.1 - 4.6e-07 29.4 2.6 1.2e-06 28.0 1.8 1.8 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_4 PF15227.1 KLO17670.1 - 0.00076 19.2 6.4 0.0019 18.0 4.4 1.8 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.1 KLO17670.1 - 0.067 12.7 6.7 0.17 11.4 4.6 1.7 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain p450 PF00067.17 KLO17671.1 - 1.6e-66 224.7 0.0 2.1e-66 224.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 FAD_binding_3 PF01494.14 KLO17673.1 - 1e-15 57.6 0.0 1.5e-15 57.1 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 KLO17673.1 - 2.3e-06 27.5 0.0 6.9e-06 25.9 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 KLO17673.1 - 1.6e-05 24.0 0.3 0.00092 18.2 0.3 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 KLO17673.1 - 0.00014 20.8 0.7 0.00025 20.0 0.0 1.7 2 0 0 2 2 2 1 FAD binding domain Amino_oxidase PF01593.19 KLO17673.1 - 0.00086 18.4 0.7 0.12 11.4 0.0 3.2 3 0 0 3 3 3 1 Flavin containing amine oxidoreductase Pyr_redox_2 PF07992.9 KLO17673.1 - 0.0009 19.1 0.0 0.0059 16.5 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 KLO17673.1 - 0.0014 18.9 0.1 0.0037 17.6 0.1 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase RNase_H PF00075.19 KLO17673.1 - 0.014 15.7 0.0 0.026 14.8 0.0 1.4 1 0 0 1 1 1 0 RNase H Thi4 PF01946.12 KLO17673.1 - 0.037 13.1 0.2 0.083 11.9 0.1 1.5 1 1 0 1 1 1 0 Thi4 family HI0933_like PF03486.9 KLO17673.1 - 0.17 10.2 0.0 0.61 8.4 0.0 1.7 2 0 0 2 2 2 0 HI0933-like protein UbiA PF01040.13 KLO17674.1 - 1.4e-17 63.8 6.8 2e-17 63.2 4.7 1.2 1 0 0 1 1 1 1 UbiA prenyltransferase family ATP1G1_PLM_MAT8 PF02038.11 KLO17674.1 - 0.053 12.5 1.2 0.075 12.0 0.1 1.7 2 0 0 2 2 2 0 ATP1G1/PLM/MAT8 family Ndc1_Nup PF09531.5 KLO17675.1 - 0.0082 14.6 5.1 0.012 14.0 3.6 1.1 1 0 0 1 1 1 1 Nucleoporin protein Ndc1-Nup p450 PF00067.17 KLO17676.1 - 6.3e-68 229.3 0.0 9.3e-68 228.8 0.0 1.3 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 KLO17677.1 - 4.2e-70 236.5 0.0 4.8e-70 236.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 KLO17678.1 - 7.1e-20 70.9 0.0 7.9e-20 70.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 KLO17679.1 - 2.3e-36 125.3 0.0 3.1e-36 124.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 UPF0102 PF02021.12 KLO17679.1 - 0.081 12.8 0.0 1.1 9.2 0.0 2.2 2 0 0 2 2 2 0 Uncharacterised protein family UPF0102 Rer1 PF03248.8 KLO17680.1 - 1.1e-73 246.6 1.0 1.2e-73 246.4 0.7 1.0 1 0 0 1 1 1 1 Rer1 family DUF2208 PF09973.4 KLO17680.1 - 0.024 13.8 3.8 0.037 13.2 2.7 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2208) WBP-1 PF11669.3 KLO17680.1 - 0.87 9.7 4.3 3.3 7.8 0.6 2.7 2 1 1 3 3 3 0 WW domain-binding protein 1 Steroid_dh PF02544.11 KLO17681.1 - 8.2e-28 97.0 8.0 9.5e-18 64.3 0.9 2.9 2 1 0 2 2 2 2 3-oxo-5-alpha-steroid 4-dehydrogenase DUF1295 PF06966.7 KLO17681.1 - 4e-05 23.0 0.1 6.7e-05 22.2 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) WD40 PF00400.27 KLO17682.1 - 8.6e-29 98.3 16.3 3.1e-09 36.3 0.9 6.6 6 1 0 6 6 6 6 WD domain, G-beta repeat eIF2A PF08662.6 KLO17682.1 - 0.0082 15.8 0.0 0.1 12.3 0.0 2.4 2 1 1 3 3 3 1 Eukaryotic translation initiation factor eIF2A AAA_17 PF13207.1 KLO17683.1 - 0.00012 22.9 0.0 0.0003 21.6 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 KLO17683.1 - 0.00099 19.1 0.0 0.0016 18.4 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain AAA_30 PF13604.1 KLO17683.1 - 0.032 13.8 0.0 0.054 13.0 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 KLO17683.1 - 0.055 13.7 0.0 0.11 12.8 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA_33 PF13671.1 KLO17683.1 - 0.063 13.1 0.0 0.2 11.5 0.0 1.8 2 0 0 2 2 2 0 AAA domain KAP_NTPase PF07693.9 KLO17683.1 - 0.11 11.4 0.0 0.12 11.3 0.0 1.2 1 0 0 1 1 1 0 KAP family P-loop domain Zeta_toxin PF06414.7 KLO17683.1 - 0.12 11.4 0.0 0.19 10.8 0.0 1.2 1 0 0 1 1 1 0 Zeta toxin AAA_5 PF07728.9 KLO17683.1 - 0.15 11.8 0.0 2.1 8.1 0.0 2.2 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) MIF4G PF02854.14 KLO17685.1 - 8.3e-35 120.0 0.1 9.5e-35 119.9 0.0 1.0 1 0 0 1 1 1 1 MIF4G domain MIF4G PF02854.14 KLO17686.1 - 2.6e-33 115.2 7.5 4.5e-33 114.4 5.2 1.3 1 1 0 1 1 1 1 MIF4G domain WGG PF10273.4 KLO17686.1 - 0.0065 16.5 1.6 2.7 8.1 0.0 3.2 4 1 0 4 4 4 2 Pre-rRNA-processing protein TSR2 AF0941-like PF14591.1 KLO17686.1 - 0.21 11.6 7.1 5.3 7.1 0.1 3.3 2 1 2 4 4 4 0 AF0941-like MIF4G PF02854.14 KLO17687.1 - 1.9e-28 99.3 0.0 2.2e-28 99.1 0.0 1.0 1 0 0 1 1 1 1 MIF4G domain MOZART1 PF12554.3 KLO17687.1 - 0.038 13.4 0.4 0.081 12.4 0.1 1.7 2 0 0 2 2 2 0 Mitotic-spindle organizing gamma-tubulin ring associated MIF4G PF02854.14 KLO17689.1 - 1.3e-47 161.9 2.7 5.9e-47 159.7 1.7 2.1 2 0 0 2 2 2 1 MIF4G domain eIF_4G1 PF12152.3 KLO17689.1 - 3.1e-16 59.0 0.0 1.2e-15 57.1 0.0 2.1 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 4G1 MA3 PF02847.12 KLO17689.1 - 9.9e-11 41.3 0.8 1.4e-09 37.5 0.0 2.7 3 0 0 3 3 3 1 MA3 domain Peptidase_C14 PF00656.17 KLO17690.1 - 5.7e-48 163.7 0.0 7.4e-48 163.4 0.0 1.0 1 0 0 1 1 1 1 Caspase domain Abhydro_lipase PF04083.11 KLO17691.1 - 2.7e-21 74.6 0.1 5.3e-21 73.7 0.0 1.5 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Abhydrolase_1 PF00561.15 KLO17691.1 - 1.3e-13 51.0 0.4 8.5e-13 48.3 0.3 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 KLO17691.1 - 9.5e-09 35.4 0.1 2e-08 34.3 0.1 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KLO17691.1 - 4e-06 26.6 0.0 2.4e-05 24.1 0.0 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family FSH1 PF03959.8 KLO17691.1 - 0.0042 16.5 0.2 0.23 10.8 0.0 2.5 2 1 0 2 2 2 1 Serine hydrolase (FSH1) Abhydrolase_2 PF02230.11 KLO17691.1 - 0.11 11.8 0.0 7.8 5.8 0.0 2.6 3 0 0 3 3 3 0 Phospholipase/Carboxylesterase ADC PF06314.6 KLO17692.1 - 0.049 12.9 0.0 0.08 12.2 0.0 1.3 1 0 0 1 1 1 0 Acetoacetate decarboxylase (ADC) ADC PF06314.6 KLO17693.1 - 0.01 15.2 0.0 0.016 14.5 0.0 1.2 1 0 0 1 1 1 0 Acetoacetate decarboxylase (ADC) Methyltransf_23 PF13489.1 KLO17695.1 - 1.3e-10 41.2 0.0 2e-10 40.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KLO17695.1 - 4.8e-10 39.8 0.0 1.2e-09 38.5 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KLO17695.1 - 2.2e-09 37.1 0.0 1.1e-08 34.8 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KLO17695.1 - 6.2e-09 35.3 0.0 7.7e-08 31.7 0.0 2.5 3 1 0 3 3 3 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.1 KLO17695.1 - 2.5e-07 30.9 0.0 6.1e-07 29.7 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KLO17695.1 - 3.4e-07 30.6 0.0 1.5e-06 28.5 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.14 KLO17695.1 - 0.00028 20.9 0.0 0.00035 20.5 0.0 1.2 1 0 0 1 1 1 1 FtsJ-like methyltransferase TPMT PF05724.6 KLO17695.1 - 0.00061 19.3 0.0 0.00089 18.7 0.0 1.2 1 0 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) Methyltransf_18 PF12847.2 KLO17695.1 - 0.001 19.6 0.0 0.021 15.3 0.0 2.6 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 KLO17695.1 - 0.0069 16.4 0.0 0.15 12.1 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain DUF218 PF02698.12 KLO17696.1 - 5.2e-05 22.7 0.0 8.4e-05 22.1 0.0 1.4 1 0 0 1 1 1 1 DUF218 domain DUF4658 PF15555.1 KLO17696.1 - 0.12 12.2 0.2 0.23 11.3 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4658) Glyco_hydro_61 PF03443.9 KLO17697.1 - 1e-61 208.5 1.1 1.5e-61 207.9 0.7 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 CBM_1 PF00734.13 KLO17697.1 - 1.1e-12 47.4 6.6 1.1e-12 47.4 4.6 3.1 3 0 0 3 3 3 1 Fungal cellulose binding domain Toxin_7 PF05980.7 KLO17697.1 - 0.069 13.1 0.2 0.069 13.1 0.2 2.2 2 0 0 2 2 2 0 Toxin 7 SR-25 PF10500.4 KLO17698.1 - 0.9 8.9 16.5 1.6 8.1 11.4 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein rve_3 PF13683.1 KLO17700.1 - 0.12 11.8 0.0 0.24 10.9 0.0 1.4 1 0 0 1 1 1 0 Integrase core domain DcuA_DcuB PF03605.9 KLO17701.1 - 0.16 10.7 0.5 0.22 10.3 0.3 1.3 1 0 0 1 1 1 0 Anaerobic c4-dicarboxylate membrane transporter DUF883 PF05957.8 KLO17701.1 - 3.8 7.9 5.7 23 5.4 0.0 3.2 3 1 0 3 3 3 0 Bacterial protein of unknown function (DUF883) F-box PF00646.28 KLO17702.1 - 7.1e-10 38.2 0.7 1.5e-09 37.2 0.5 1.6 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 KLO17702.1 - 1.9e-07 30.6 0.5 5.5e-07 29.2 0.3 1.8 1 0 0 1 1 1 1 F-box-like MFS_1 PF07690.11 KLO17703.1 - 6.8e-35 120.4 29.3 6.8e-35 120.4 20.3 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF3733 PF12534.3 KLO17703.1 - 0.049 12.9 0.0 0.14 11.4 0.0 1.7 1 0 0 1 1 1 0 Leucine-rich repeat containing protein 8 TPR_11 PF13414.1 KLO17704.1 - 5.2e-17 61.2 7.6 9.7e-09 34.7 0.1 3.9 2 1 2 4 4 4 3 TPR repeat PB1 PF00564.19 KLO17704.1 - 1.9e-14 53.0 0.0 3.7e-14 52.1 0.0 1.5 1 0 0 1 1 1 1 PB1 domain TPR_1 PF00515.23 KLO17704.1 - 6.9e-14 50.7 2.3 3.2e-05 23.3 0.0 5.3 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_2 PF07719.12 KLO17704.1 - 3e-11 42.3 8.2 0.0022 17.7 0.0 5.1 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_12 PF13424.1 KLO17704.1 - 1.1e-08 34.9 4.8 0.00053 19.8 0.1 4.1 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.1 KLO17704.1 - 5.7e-07 28.8 1.9 0.00068 19.2 0.0 4.7 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_6 PF13174.1 KLO17704.1 - 0.00028 21.1 5.3 34 5.1 0.0 5.9 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_7 PF13176.1 KLO17704.1 - 0.00049 19.6 3.3 0.0074 16.0 0.0 4.0 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_10 PF13374.1 KLO17704.1 - 0.0015 18.3 0.9 0.69 9.9 0.0 4.0 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_17 PF13431.1 KLO17704.1 - 0.0032 17.5 0.1 1.9 8.9 0.0 3.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.1 KLO17704.1 - 0.0076 16.9 15.3 0.0091 16.6 0.3 4.3 5 0 0 5 5 4 1 Tetratricopeptide repeat Apc3 PF12895.2 KLO17704.1 - 0.0078 16.3 0.4 0.48 10.5 0.1 2.5 1 1 1 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.1 KLO17704.1 - 0.017 15.6 11.1 0.83 10.4 0.0 5.0 4 1 1 5 5 4 0 Tetratricopeptide repeat TPR_4 PF07721.9 KLO17704.1 - 0.03 14.7 1.0 27 5.5 0.0 4.7 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_19 PF14559.1 KLO17704.1 - 0.053 13.8 7.6 0.17 12.2 0.2 3.4 3 1 0 3 3 2 0 Tetratricopeptide repeat TPR_9 PF13371.1 KLO17704.1 - 0.24 11.2 1.6 2.2 8.1 0.1 3.2 2 1 1 3 3 3 0 Tetratricopeptide repeat Fungal_trans PF04082.13 KLO17705.1 - 7.6e-09 34.8 0.0 1.2e-08 34.2 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KLO17705.1 - 6.8e-07 29.1 8.5 1.1e-06 28.4 5.9 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pyridoxal_deC PF00282.14 KLO17707.1 - 2.8e-19 68.8 0.0 9.5e-09 34.1 0.0 3.1 3 0 0 3 3 3 3 Pyridoxal-dependent decarboxylase conserved domain HSP70 PF00012.15 KLO17708.1 - 1e-264 879.0 16.0 1.2e-264 878.8 11.1 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 KLO17708.1 - 2.4e-15 55.9 4.0 2.3e-13 49.4 1.4 2.3 2 0 0 2 2 2 2 MreB/Mbl protein FtsA PF14450.1 KLO17708.1 - 0.0038 17.0 11.3 0.57 10.0 0.2 4.5 4 1 0 4 4 4 2 Cell division protein FtsA TipAS PF07739.8 KLO17708.1 - 0.3 11.4 4.1 0.74 10.1 2.8 1.6 1 0 0 1 1 1 0 TipAS antibiotic-recognition domain APH PF01636.18 KLO17709.1 - 2.2e-35 122.5 0.0 2.9e-35 122.1 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 KLO17709.1 - 4.8e-06 26.3 0.0 4.7e-05 23.0 0.0 2.0 2 0 0 2 2 2 1 Choline/ethanolamine kinase EcKinase PF02958.15 KLO17709.1 - 1.9e-05 23.9 0.0 5.2e-05 22.5 0.0 1.6 2 0 0 2 2 2 1 Ecdysteroid kinase Arrestin_C PF02752.17 KLO17712.1 - 1.5e-16 60.7 0.0 1.5e-14 54.2 0.0 2.6 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.24 KLO17712.1 - 1.6e-12 47.4 0.2 2.1e-10 40.6 0.0 2.5 2 0 0 2 2 2 2 Arrestin (or S-antigen), N-terminal domain LDB19 PF13002.2 KLO17712.1 - 0.05 13.0 0.0 0.1 12.0 0.0 1.4 1 0 0 1 1 1 0 Arrestin_N terminal like DEAD PF00270.24 KLO17713.1 - 0.097 12.1 0.0 0.19 11.1 0.0 1.5 1 0 0 1 1 1 0 DEAD/DEAH box helicase Pkinase PF00069.20 KLO17715.1 - 7.3e-40 136.7 0.0 1.1e-39 136.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KLO17715.1 - 2.4e-31 108.7 0.0 3.3e-31 108.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KLO17715.1 - 3.3e-06 26.2 0.0 5.8e-06 25.4 0.0 1.4 1 1 0 1 1 1 1 Kinase-like IMS PF00817.15 KLO17715.1 - 0.042 13.6 0.0 0.31 10.8 0.0 2.2 1 1 0 1 1 1 0 impB/mucB/samB family BP28CT PF08146.7 KLO17716.1 - 9.7e-26 90.3 1.4 3.4e-25 88.5 0.3 2.6 2 0 0 2 2 2 1 BP28CT (NUC211) domain U3snoRNP10 PF12397.3 KLO17716.1 - 2.6e-08 33.8 0.7 2.6e-08 33.8 0.5 5.7 6 0 0 6 6 6 1 U3 small nucleolar RNA-associated protein 10 Gal-3-0_sulfotr PF06990.6 KLO17716.1 - 0.0035 16.0 0.1 0.0071 15.0 0.0 1.4 1 0 0 1 1 1 1 Galactose-3-O-sulfotransferase HEAT PF02985.17 KLO17716.1 - 0.0054 16.7 12.7 0.0072 16.3 0.1 5.4 5 0 0 5 5 5 1 HEAT repeat HEAT_EZ PF13513.1 KLO17716.1 - 0.027 14.9 0.4 0.027 14.9 0.3 5.0 6 0 0 6 6 6 0 HEAT-like repeat HEAT_2 PF13646.1 KLO17716.1 - 0.21 11.9 19.9 0.63 10.3 0.0 7.0 6 2 1 7 7 7 0 HEAT repeats DUF1365 PF07103.6 KLO17717.1 - 9.6e-37 126.3 0.0 3.2e-36 124.7 0.0 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF1365) F-box-like PF12937.2 KLO17718.1 - 2.8e-07 30.1 0.2 4.8e-07 29.3 0.1 1.4 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KLO17718.1 - 0.00011 21.7 0.1 0.00018 21.0 0.1 1.3 1 0 0 1 1 1 1 F-box domain PPR_2 PF13041.1 KLO17719.1 - 8e-07 28.9 0.0 0.034 14.1 0.0 4.8 6 0 0 6 6 6 2 PPR repeat family PPR_3 PF13812.1 KLO17719.1 - 0.00094 19.2 0.9 27 5.4 0.0 5.6 5 0 0 5 5 5 1 Pentatricopeptide repeat domain DUF4357 PF14267.1 KLO17719.1 - 0.031 13.8 0.4 0.069 12.7 0.3 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4357) PPR_1 PF12854.2 KLO17719.1 - 0.086 12.3 0.0 5.4 6.5 0.0 3.0 2 0 0 2 2 2 0 PPR repeat PP28 PF10252.4 KLO17720.1 - 2.3e-05 24.3 1.5 2.3e-05 24.3 1.0 2.9 2 1 0 2 2 2 1 Casein kinase substrate phosphoprotein PP28 DNA_pol_phi PF04931.8 KLO17720.1 - 0.38 8.4 25.1 0.43 8.2 17.4 1.1 1 0 0 1 1 1 0 DNA polymerase phi Daxx PF03344.10 KLO17720.1 - 1.1 7.6 23.7 1.4 7.3 16.4 1.1 1 0 0 1 1 1 0 Daxx Family Neur_chan_memb PF02932.11 KLO17720.1 - 1.4 8.7 5.0 1.9 8.3 3.5 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Complex1_LYR PF05347.10 KLO17721.1 - 3e-10 39.7 0.7 4.6e-10 39.1 0.5 1.3 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 KLO17721.1 - 2.4e-08 34.0 0.2 4.2e-08 33.2 0.2 1.4 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR_2 PF13233.1 KLO17721.1 - 0.019 15.4 0.0 0.027 14.9 0.0 1.2 1 0 0 1 1 1 0 Complex1_LYR-like RRM_1 PF00076.17 KLO17722.1 - 8.2e-14 50.9 0.0 1.1e-13 50.5 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KLO17722.1 - 3.4e-11 42.9 0.0 5e-11 42.4 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KLO17722.1 - 1.8e-07 30.8 0.0 2.5e-07 30.4 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF1777 PF08648.7 KLO17722.1 - 0.05 13.3 40.4 0.087 12.5 28.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1777) Nup35_RRM_2 PF14605.1 KLO17722.1 - 0.055 13.2 0.0 0.084 12.6 0.0 1.2 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif GTP_EFTU PF00009.22 KLO17723.1 - 3.1e-37 127.8 0.0 5e-37 127.1 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain eIF2_C PF09173.6 KLO17723.1 - 7.2e-31 106.0 0.0 1.6e-30 104.9 0.0 1.6 1 0 0 1 1 1 1 Initiation factor eIF2 gamma, C terminal GTP_EFTU_D2 PF03144.20 KLO17723.1 - 4e-10 39.6 0.0 1e-09 38.3 0.0 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 KLO17723.1 - 0.012 15.5 0.0 0.025 14.5 0.0 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase Dynamin_N PF00350.18 KLO17723.1 - 0.39 10.5 2.6 0.29 10.9 0.1 2.3 2 1 0 2 2 2 0 Dynamin family RINGv PF12906.2 KLO17725.1 - 2.4e-06 27.4 7.9 3.8e-06 26.8 5.5 1.3 1 0 0 1 1 1 1 RING-variant domain FANCL_C PF11793.3 KLO17725.1 - 5.9e-05 22.9 4.0 9.7e-05 22.2 2.8 1.3 1 0 0 1 1 1 1 FANCL C-terminal domain zf-RING_2 PF13639.1 KLO17725.1 - 0.0045 16.8 6.1 0.0075 16.0 4.3 1.4 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 KLO17725.1 - 0.055 13.5 3.9 0.098 12.7 2.7 1.4 1 0 0 1 1 1 0 RING-H2 zinc finger zinc_ribbon_2 PF13240.1 KLO17725.1 - 0.14 11.7 0.6 0.25 10.8 0.4 1.4 1 0 0 1 1 1 0 zinc-ribbon domain zf-primase PF09329.6 KLO17726.1 - 4e-10 39.1 1.9 7.6e-10 38.2 1.3 1.5 1 0 0 1 1 1 1 Primase zinc finger Ish1 PF10281.4 KLO17727.1 - 3.5e-43 145.2 40.7 1.9e-09 37.4 0.1 8.0 8 0 0 8 8 8 7 Putative stress-responsive nuclear envelope protein HeH PF12949.2 KLO17727.1 - 3.9e-05 23.1 10.2 0.021 14.3 0.0 7.0 8 1 0 8 8 8 2 HeH/LEM domain SAP PF02037.22 KLO17727.1 - 9.2e-05 21.8 0.0 11 5.6 0.0 5.1 5 1 0 5 5 5 2 SAP domain DUF1470 PF07336.6 KLO17727.1 - 0.058 13.7 1.0 2.9 8.2 0.0 3.8 3 1 1 4 4 4 0 Protein of unknown function (DUF1470) SAM_2 PF07647.12 KLO17727.1 - 0.078 12.8 7.3 13 5.6 0.1 5.1 5 0 0 5 5 5 0 SAM domain (Sterile alpha motif) GntR PF00392.16 KLO17727.1 - 0.087 12.2 0.5 0.35 10.3 0.1 2.3 2 0 0 2 2 2 0 Bacterial regulatory proteins, gntR family WD40 PF00400.27 KLO17730.1 - 0.00052 19.7 0.2 0.62 10.0 0.0 3.6 3 0 0 3 3 3 2 WD domain, G-beta repeat ToxN_toxin PF13958.1 KLO17730.1 - 0.1 12.2 0.0 0.22 11.1 0.0 1.4 1 0 0 1 1 1 0 Toxin ToxN, type III toxin-antitoxin system DBB PF14545.1 KLO17730.1 - 0.11 12.0 0.3 0.33 10.4 0.3 1.7 2 0 0 2 2 2 0 Dof, BCAP, and BANK (DBB) motif, ADH_zinc_N PF00107.21 KLO17732.1 - 7.8e-27 93.3 0.1 1.3e-26 92.7 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 KLO17732.1 - 2.9e-16 60.5 0.0 5e-16 59.7 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KLO17732.1 - 8.7e-12 44.7 0.2 2.1e-11 43.5 0.1 1.7 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ELFV_dehydrog PF00208.16 KLO17732.1 - 0.051 13.1 0.1 0.082 12.4 0.1 1.3 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase TrkA_N PF02254.13 KLO17732.1 - 0.074 13.0 0.0 0.13 12.2 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain Ldh_1_N PF00056.18 KLO17733.1 - 6e-44 149.2 0.1 8.7e-44 148.7 0.1 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.13 KLO17733.1 - 3e-42 144.3 0.1 4e-42 143.8 0.1 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain 3Beta_HSD PF01073.14 KLO17733.1 - 0.0097 14.6 0.0 0.013 14.1 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family THF_DHG_CYH_C PF02882.14 KLO17733.1 - 0.023 13.7 0.3 0.39 9.7 0.0 2.7 2 1 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Lon_C PF05362.8 KLO17734.1 - 3.6e-63 212.5 1.5 4.5e-63 212.2 0.5 1.6 2 0 0 2 2 2 1 Lon protease (S16) C-terminal proteolytic domain AAA PF00004.24 KLO17734.1 - 6.3e-22 78.2 0.0 1.3e-21 77.1 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) LON PF02190.11 KLO17734.1 - 2.6e-11 43.5 0.0 5.8e-11 42.4 0.0 1.6 1 0 0 1 1 1 1 ATP-dependent protease La (LON) domain AAA_5 PF07728.9 KLO17734.1 - 1.9e-10 40.6 0.0 4.7e-10 39.3 0.0 1.8 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) ChlI PF13541.1 KLO17734.1 - 2.1e-06 27.2 0.0 8e-06 25.3 0.0 2.0 1 1 0 1 1 1 1 Subunit ChlI of Mg-chelatase AAA_22 PF13401.1 KLO17734.1 - 2.9e-05 24.1 0.3 0.0081 16.2 0.0 3.4 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.1 KLO17734.1 - 4.2e-05 23.6 0.5 0.00026 21.0 0.0 2.6 3 0 0 3 3 3 1 AAA ATPase domain AAA_17 PF13207.1 KLO17734.1 - 0.00025 21.8 0.0 0.00077 20.2 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_2 PF07724.9 KLO17734.1 - 0.00037 20.4 0.0 0.0017 18.3 0.0 2.1 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_33 PF13671.1 KLO17734.1 - 0.0026 17.6 0.0 0.0059 16.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 KLO17734.1 - 0.0044 16.7 0.1 0.015 15.0 0.1 1.9 1 0 0 1 1 1 1 Part of AAA domain AAA_18 PF13238.1 KLO17734.1 - 0.0076 16.5 0.1 0.15 12.3 0.0 2.6 2 0 0 2 2 2 1 AAA domain RuvB_N PF05496.7 KLO17734.1 - 0.0095 15.0 0.0 0.055 12.5 0.0 2.1 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus TIP49 PF06068.8 KLO17734.1 - 0.016 13.9 0.0 0.11 11.2 0.0 2.1 2 0 0 2 2 2 0 TIP49 C-terminus Viral_helicase1 PF01443.13 KLO17734.1 - 0.017 14.6 0.0 0.031 13.8 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_25 PF13481.1 KLO17734.1 - 0.026 13.9 0.0 0.08 12.3 0.0 1.8 2 0 0 2 2 1 0 AAA domain AAA_3 PF07726.6 KLO17734.1 - 0.034 13.7 0.0 0.092 12.3 0.0 1.8 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) MobB PF03205.9 KLO17734.1 - 0.04 13.6 0.0 0.093 12.4 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_14 PF13173.1 KLO17734.1 - 0.044 13.6 0.0 0.088 12.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.16 KLO17734.1 - 0.066 12.3 0.1 0.51 9.4 0.0 2.2 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.12 KLO17734.1 - 0.067 12.6 0.0 0.16 11.3 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein RNA_helicase PF00910.17 KLO17734.1 - 0.11 12.6 0.0 0.29 11.3 0.0 1.7 1 0 0 1 1 1 0 RNA helicase AAA_21 PF13304.1 KLO17734.1 - 0.18 11.6 0.0 2.2 8.1 0.0 2.2 1 1 1 2 2 2 0 AAA domain AAA_23 PF13476.1 KLO17734.1 - 0.19 12.0 2.3 2.4 8.4 0.0 2.8 3 0 0 3 3 3 0 AAA domain DUF3138 PF11336.3 KLO17734.1 - 0.82 7.7 1.4 1.4 7.0 1.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) MFS_1 PF07690.11 KLO17736.1 - 3.4e-23 81.9 29.6 2e-12 46.5 11.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF4407 PF14362.1 KLO17736.1 - 0.021 13.7 3.2 0.047 12.6 2.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Tropomyosin_1 PF12718.2 KLO17737.1 - 0.0032 17.3 18.4 0.0032 17.3 12.8 5.3 2 1 3 5 5 5 1 Tropomyosin like Reo_sigmaC PF04582.7 KLO17737.1 - 0.0096 15.1 33.7 0.025 13.7 1.6 5.2 2 2 2 5 5 5 4 Reovirus sigma C capsid protein AAA_13 PF13166.1 KLO17737.1 - 0.18 10.2 65.8 0.043 12.2 14.7 3.3 2 1 1 3 3 3 0 AAA domain NPV_P10 PF05531.7 KLO17737.1 - 0.94 9.7 28.2 7.2 6.9 2.6 6.8 5 3 0 5 5 5 0 Nucleopolyhedrovirus P10 protein IncA PF04156.9 KLO17737.1 - 1.4 8.4 106.6 0.14 11.7 11.2 7.1 2 1 5 7 7 7 0 IncA protein CTP_transf_2 PF01467.21 KLO17738.1 - 1.6e-16 60.7 0.0 2.9e-16 59.9 0.0 1.5 1 0 0 1 1 1 1 Cytidylyltransferase SapA PF02199.10 KLO17738.1 - 0.049 13.4 0.4 0.087 12.6 0.3 1.4 1 0 0 1 1 1 0 Saposin A-type domain TFIIE_beta PF02186.10 KLO17739.1 - 0.052 13.5 0.1 0.18 11.8 0.0 1.9 2 0 0 2 2 2 0 TFIIE beta subunit core domain DUF2697 PF10906.3 KLO17739.1 - 0.068 13.1 0.0 0.17 11.8 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2697) Pkinase PF00069.20 KLO17740.1 - 0.0018 17.4 0.0 0.0039 16.3 0.0 1.5 2 0 0 2 2 2 1 Protein kinase domain PAP_assoc PF03828.14 KLO17741.1 - 7.5e-19 67.4 0.8 2e-18 66.0 0.2 2.0 2 0 0 2 2 2 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.18 KLO17741.1 - 1.2e-05 25.4 0.0 2.9e-05 24.3 0.0 1.6 1 0 0 1 1 1 1 Nucleotidyltransferase domain LSM PF01423.17 KLO17742.1 - 1.4e-16 59.7 0.0 1.9e-16 59.3 0.0 1.2 1 0 0 1 1 1 1 LSM domain HEAT PF02985.17 KLO17743.1 - 5.1e-15 54.1 15.3 0.0015 18.4 0.0 9.7 11 0 0 11 11 11 4 HEAT repeat HEAT_EZ PF13513.1 KLO17743.1 - 1.5e-14 53.9 19.1 3.9e-10 39.8 0.0 9.5 9 3 3 12 12 12 2 HEAT-like repeat HEAT_2 PF13646.1 KLO17743.1 - 1.9e-14 53.7 8.3 2.5e-05 24.4 0.0 7.4 3 2 5 8 8 8 4 HEAT repeats IBN_N PF03810.14 KLO17743.1 - 1.1e-10 41.2 3.0 1e-09 38.1 0.2 3.8 4 0 0 4 4 4 1 Importin-beta N-terminal domain Arm PF00514.18 KLO17743.1 - 5e-08 32.4 1.5 0.27 11.1 0.0 6.7 6 0 0 6 6 6 2 Armadillo/beta-catenin-like repeat CLASP_N PF12348.3 KLO17743.1 - 0.00041 19.7 0.5 0.14 11.4 0.1 4.4 2 2 4 6 6 6 1 CLASP N terminal V1R PF03402.9 KLO17743.1 - 0.067 12.5 0.2 0.12 11.7 0.2 1.3 1 0 0 1 1 1 0 Vomeronasal organ pheromone receptor family, V1R Amidohydro_3 PF07969.6 KLO17744.1 - 1.2e-65 222.3 0.0 1.4e-65 222.1 0.0 1.0 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_1 PF01979.15 KLO17744.1 - 6.8e-08 32.5 0.0 0.001 18.7 0.0 2.8 2 1 0 2 2 2 2 Amidohydrolase family Amidohydro_5 PF13594.1 KLO17744.1 - 8.8e-06 25.4 0.3 2.5e-05 23.9 0.2 1.8 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_4 PF13147.1 KLO17744.1 - 0.0017 18.4 0.1 1.2 9.1 0.0 2.3 2 0 0 2 2 2 2 Amidohydrolase DSPc PF00782.15 KLO17745.1 - 1.6e-23 82.7 0.0 2.7e-23 81.9 0.0 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Rhodanese PF00581.15 KLO17745.1 - 0.00011 22.4 0.0 0.00031 21.0 0.0 1.8 2 0 0 2 2 2 1 Rhodanese-like domain Y_phosphatase3 PF13350.1 KLO17745.1 - 0.13 12.5 0.0 0.26 11.5 0.0 1.4 1 0 0 1 1 1 0 Tyrosine phosphatase family Y_phosphatase PF00102.22 KLO17745.1 - 0.23 10.7 0.0 0.37 10.0 0.0 1.2 1 0 0 1 1 1 0 Protein-tyrosine phosphatase Y_phosphatase2 PF03162.8 KLO17745.1 - 0.25 10.6 0.0 0.49 9.7 0.0 1.4 1 0 0 1 1 1 0 Tyrosine phosphatase family eIF-5a PF01287.15 KLO17747.1 - 1.5e-25 88.8 0.5 2.2e-25 88.3 0.4 1.2 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold KOW PF00467.24 KLO17747.1 - 1.7e-05 24.3 1.5 4e-05 23.1 1.0 1.6 1 0 0 1 1 1 1 KOW motif EFP_N PF08207.7 KLO17747.1 - 0.081 12.8 0.1 0.13 12.1 0.0 1.4 1 0 0 1 1 1 0 Elongation factor P (EF-P) KOW-like domain CUE PF02845.11 KLO17748.1 - 9.8e-11 40.9 0.0 1.8e-10 40.0 0.0 1.5 1 0 0 1 1 1 1 CUE domain DUF3697 PF12478.3 KLO17748.1 - 0.0033 17.0 0.2 0.019 14.5 0.1 2.3 2 0 0 2 2 2 1 Ubiquitin-associated protein 2 DUF159 PF02586.9 KLO17749.1 - 4.6e-52 176.5 0.1 6.6e-52 176.0 0.1 1.2 1 0 0 1 1 1 1 Uncharacterised ACR, COG2135 Bromo_TP PF07524.8 KLO17750.1 - 4.2e-09 35.9 0.2 2.1e-08 33.7 0.1 2.0 2 0 0 2 2 2 1 Bromodomain associated CENP-S PF15630.1 KLO17750.1 - 0.13 12.4 0.1 0.31 11.2 0.1 1.6 1 0 0 1 1 1 0 Kinetochore component CENP-S SMN PF06003.7 KLO17750.1 - 3.3 6.7 8.9 9.2 5.2 6.2 1.7 1 0 0 1 1 1 0 Survival motor neuron protein (SMN) Apc1 PF12859.2 KLO17751.1 - 6.9e-09 35.8 0.0 2.4e-08 34.1 0.0 2.0 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 1 PC_rep PF01851.17 KLO17751.1 - 6.5e-06 26.1 9.7 0.051 13.8 0.0 5.4 5 0 0 5 5 5 2 Proteasome/cyclosome repeat DUF1793 PF08760.6 KLO17752.1 - 5.1e-39 133.8 0.0 1.5e-38 132.3 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1793) MatE PF01554.13 KLO17753.1 - 1.1e-36 125.8 11.2 3e-23 82.2 3.7 2.8 2 1 0 2 2 2 2 MatE Arginase PF00491.16 KLO17754.1 - 3e-84 282.6 0.0 3.8e-84 282.2 0.0 1.1 1 0 0 1 1 1 1 Arginase family UPF0489 PF12640.2 KLO17754.1 - 0.1 12.8 0.0 0.16 12.1 0.0 1.3 1 0 0 1 1 1 0 UPF0489 domain AA_permease_2 PF13520.1 KLO17755.1 - 1.4e-56 191.8 54.1 1.7e-56 191.5 37.5 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 KLO17755.1 - 1.6e-21 76.2 47.4 2.1e-21 75.8 32.8 1.1 1 0 0 1 1 1 1 Amino acid permease Glucodextran_B PF09136.5 KLO17755.1 - 0.17 12.0 3.2 1.7 8.9 0.3 3.0 2 0 0 2 2 2 0 Glucodextranase, domain B DUF1129 PF06570.6 KLO17755.1 - 0.19 10.9 5.8 0.95 8.7 4.0 2.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1129) LRR_4 PF12799.2 KLO17757.1 - 0.00043 19.8 0.1 3.6 7.3 0.2 3.7 3 1 0 3 3 3 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KLO17757.1 - 0.0017 18.0 1.5 2.3 8.0 0.0 3.2 3 0 0 3 3 3 2 Leucine rich repeat LRR_1 PF00560.28 KLO17757.1 - 0.042 13.8 1.0 17 5.9 0.1 3.5 2 1 0 2 2 2 0 Leucine Rich Repeat LRR_6 PF13516.1 KLO17757.1 - 0.054 13.5 0.5 88 3.6 0.0 4.6 4 0 0 4 4 4 0 Leucine Rich repeat LRR_7 PF13504.1 KLO17757.1 - 0.31 11.4 8.3 4.3 7.9 0.0 5.1 5 0 0 5 5 5 0 Leucine rich repeat zf-DHHC PF01529.15 KLO17758.1 - 2.9e-39 134.2 0.9 4.1e-39 133.7 0.1 1.6 1 1 1 2 2 2 1 DHHC palmitoyltransferase Colicin_V PF02674.11 KLO17758.1 - 0.36 10.6 5.2 5.3 6.8 1.3 2.2 2 0 0 2 2 2 0 Colicin V production protein Aminotran_3 PF00202.16 KLO17759.1 - 3.6e-108 361.4 0.0 4.5e-108 361.0 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III Beta_elim_lyase PF01212.16 KLO17759.1 - 0.0019 17.4 0.0 0.0068 15.5 0.0 1.8 1 1 0 1 1 1 1 Beta-eliminating lyase DUF2007 PF09413.5 KLO17759.1 - 0.09 12.6 0.1 12 5.8 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF2007) dCMP_cyt_deam_1 PF00383.17 KLO17760.1 - 5.8e-11 41.9 0.3 1.9e-07 30.6 0.0 2.3 2 0 0 2 2 2 2 Cytidine and deoxycytidylate deaminase zinc-binding region DUF612 PF04747.7 KLO17760.1 - 0.0085 15.0 0.2 0.012 14.5 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function, DUF612 zf-MYND PF01753.13 KLO17762.1 - 1.3e-10 40.9 11.9 1.3e-10 40.9 8.3 2.7 3 0 0 3 3 3 1 MYND finger ESSS PF10183.4 KLO17762.1 - 0.11 12.9 0.9 0.18 12.1 0.1 1.8 2 0 0 2 2 2 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) zf-Mss51 PF13824.1 KLO17762.1 - 5.9 6.8 11.9 0.19 11.6 3.6 2.0 2 1 0 2 2 2 0 Zinc-finger of mitochondrial splicing suppressor 51 zf-MYND PF01753.13 KLO17763.1 - 5.1e-11 42.2 14.3 5.1e-11 42.2 9.9 2.2 2 0 0 2 2 2 1 MYND finger Ecl1 PF12855.2 KLO17763.1 - 0.33 10.2 5.4 0.21 10.9 1.4 2.3 2 0 0 2 2 2 0 Life-span regulatory factor zf-Mss51 PF13824.1 KLO17763.1 - 2.5 8.0 11.3 0.29 10.9 4.9 1.7 2 0 0 2 2 2 0 Zinc-finger of mitochondrial splicing suppressor 51 Zip PF02535.17 KLO17766.1 - 2.7 6.9 8.2 3.5 6.5 5.7 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter DUF1719 PF08224.6 KLO17767.1 - 0.023 13.7 0.1 0.039 13.0 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1719) ERM PF00769.14 KLO17770.1 - 4.9 6.6 32.0 0.076 12.5 15.8 2.0 1 1 1 2 2 2 0 Ezrin/radixin/moesin family DUF3597 PF12200.3 KLO17770.1 - 5.8 7.3 16.6 2.3 8.5 1.7 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF3597) zf-MYND PF01753.13 KLO17771.1 - 3.1e-11 42.9 12.4 3.1e-11 42.9 8.6 2.2 3 0 0 3 3 3 1 MYND finger Ecl1 PF12855.2 KLO17771.1 - 0.1 11.8 2.2 0.15 11.3 0.1 2.2 2 0 0 2 2 2 0 Life-span regulatory factor Baculo_PEP_C PF04513.7 KLO17772.1 - 0.003 17.4 0.3 0.007 16.1 0.1 1.7 2 0 0 2 2 2 1 Baculovirus polyhedron envelope protein, PEP, C terminus Saw1 PF11561.3 KLO17772.1 - 0.19 11.1 0.0 0.26 10.6 0.0 1.2 1 0 0 1 1 1 0 Single strand annealing-weakened 1 DUF1732 PF08340.6 KLO17772.1 - 0.32 10.8 1.7 0.79 9.5 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1732) LIM PF00412.17 KLO17775.1 - 8e-25 86.6 24.8 5.5e-13 48.7 5.5 2.2 2 0 0 2 2 2 2 LIM domain zf-RanBP PF00641.13 KLO17776.1 - 0.0072 15.4 6.6 0.02 13.9 2.5 2.4 2 0 0 2 2 2 1 Zn-finger in Ran binding protein and others Herpes_glycop_H PF02489.11 KLO17776.1 - 0.016 13.2 0.1 0.022 12.7 0.1 1.1 1 0 0 1 1 1 0 Herpesvirus glycoprotein H EF1G PF00647.14 KLO17779.1 - 1.3e-38 130.9 0.0 3e-38 129.7 0.0 1.6 1 0 0 1 1 1 1 Elongation factor 1 gamma, conserved domain GST_C_2 PF13410.1 KLO17779.1 - 1.4e-12 47.3 0.0 3.7e-12 45.9 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 KLO17779.1 - 1.5e-11 44.2 0.0 3.8e-11 42.9 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 KLO17779.1 - 7.9e-11 41.8 0.0 7.9e-11 41.8 0.0 2.2 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 KLO17779.1 - 8.4e-09 35.8 0.0 3.1e-08 34.0 0.0 2.0 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 KLO17779.1 - 1.4e-07 31.6 0.0 3.7e-07 30.2 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 KLO17779.1 - 0.0033 17.4 0.0 0.0066 16.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain DAD PF02109.11 KLO17779.1 - 0.03 14.3 0.3 3 7.9 0.1 3.0 2 1 1 3 3 3 0 DAD family SpoVR PF04293.8 KLO17779.1 - 0.068 11.5 0.9 0.12 10.7 0.6 1.3 1 0 0 1 1 1 0 SpoVR like protein FAM195 PF14799.1 KLO17779.1 - 0.1 12.4 0.0 0.1 12.4 0.0 2.4 2 1 0 2 2 2 0 FAM195 family Pox_Ag35 PF03286.9 KLO17779.1 - 1.2 8.5 7.7 2 7.9 5.4 1.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Bac_rhamnosid PF05592.6 KLO17780.1 - 2.3e-26 92.1 1.2 7.2e-26 90.4 0.8 1.8 2 1 0 2 2 2 1 Bacterial alpha-L-rhamnosidase Trehalase PF01204.13 KLO17780.1 - 0.0014 17.3 0.2 0.0021 16.7 0.2 1.1 1 0 0 1 1 1 1 Trehalase DUF608 PF04685.8 KLO17780.1 - 0.039 12.6 1.0 0.063 11.9 0.7 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF608 ABA_GPCR PF12430.3 KLO17781.1 - 1.3e-35 122.2 2.6 1.3e-35 122.2 1.8 1.7 2 0 0 2 2 2 1 Abscisic acid G-protein coupled receptor DUF3735 PF12537.3 KLO17781.1 - 1.6e-07 31.2 0.4 5.9e-07 29.4 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF3735) 7tm_1 PF00001.16 KLO17781.1 - 0.022 13.9 5.0 0.11 11.6 0.0 3.0 1 1 2 3 3 3 0 7 transmembrane receptor (rhodopsin family) ABC2_membrane_2 PF12679.2 KLO17781.1 - 7.3 5.3 12.3 0.11 11.3 2.9 1.9 2 0 0 2 2 2 0 ABC-2 family transporter protein 2OG-FeII_Oxy_2 PF13532.1 KLO17782.1 - 2e-13 50.6 0.0 1.1e-12 48.2 0.0 1.9 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.15 KLO17782.1 - 2.4e-05 24.5 0.0 0.00031 20.9 0.0 2.6 3 1 0 3 3 3 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_3 PF13640.1 KLO17782.1 - 0.007 16.8 0.0 0.014 15.9 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Cullin_binding PF03556.10 KLO17784.1 - 7.8e-30 103.4 0.4 1.8e-29 102.2 0.3 1.6 1 0 0 1 1 1 1 Cullin binding UBA_4 PF14555.1 KLO17784.1 - 0.076 12.5 0.1 0.41 10.2 0.0 2.1 1 1 0 1 1 1 0 UBA-like domain MARVEL PF01284.18 KLO17786.1 - 0.00055 19.7 2.1 0.074 12.8 0.0 2.0 1 1 1 2 2 2 2 Membrane-associating domain MARVEL PF01284.18 KLO17788.1 - 0.00048 19.9 8.3 0.00073 19.3 5.7 1.3 1 0 0 1 1 1 1 Membrane-associating domain DUF996 PF06195.8 KLO17788.1 - 5.4 7.0 8.5 1.3 9.0 2.9 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF996) SKN1 PF03935.10 KLO17789.1 - 3.9e-192 638.8 5.0 4.7e-192 638.6 3.4 1.0 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) TLD PF07534.11 KLO17790.1 - 1.9e-29 102.3 0.0 3e-29 101.7 0.0 1.3 1 0 0 1 1 1 1 TLD Hexokinase_2 PF03727.11 KLO17791.1 - 1.4e-79 266.7 0.0 2.1e-79 266.1 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.16 KLO17791.1 - 1.9e-65 220.0 0.0 4.2e-35 120.9 0.0 2.2 2 0 0 2 2 2 2 Hexokinase FGGY_N PF00370.16 KLO17791.1 - 0.18 11.0 0.0 0.35 10.1 0.0 1.4 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, N-terminal domain MFS_1 PF07690.11 KLO17792.1 - 8.4e-30 103.6 30.4 1.3e-29 103.0 21.1 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily Glyco_hydro_92 PF07971.7 KLO17793.1 - 3.9e-109 365.5 0.2 1.6e-72 244.7 0.1 2.0 1 1 1 2 2 2 2 Glycosyl hydrolase family 92 WD40 PF00400.27 KLO17794.1 - 1.7e-34 116.4 22.3 1.9e-08 33.8 0.1 7.2 7 0 0 7 7 7 6 WD domain, G-beta repeat NLE PF08154.7 KLO17794.1 - 7.9e-16 57.8 0.0 1.6e-15 56.8 0.0 1.5 1 0 0 1 1 1 1 NLE (NUC135) domain Nup160 PF11715.3 KLO17794.1 - 0.0061 14.7 3.8 0.01 14.0 0.0 2.6 2 1 1 3 3 3 1 Nucleoporin Nup120/160 Aldo_ket_red PF00248.16 KLO17795.1 - 2.1e-65 220.3 0.0 2.4e-65 220.1 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Melibiase PF02065.13 KLO17796.1 - 1.4e-08 33.8 0.2 1.5e-06 27.1 0.0 2.5 3 0 0 3 3 3 2 Melibiase Melibiase PF02065.13 KLO17797.1 - 1.7e-14 53.3 0.4 9.7e-13 47.5 0.0 2.6 3 0 0 3 3 3 2 Melibiase Ribosomal_L14 PF00238.14 KLO17798.1 - 1.1e-45 154.2 0.3 1.3e-45 154.1 0.2 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e LSM PF01423.17 KLO17798.1 - 0.017 14.6 0.0 0.13 11.8 0.0 2.1 2 1 0 2 2 2 0 LSM domain BTB PF00651.26 KLO17799.1 - 0.00012 22.0 0.0 0.00041 20.3 0.0 1.9 2 0 0 2 2 2 1 BTB/POZ domain Macoilin PF09726.4 KLO17799.1 - 0.68 8.1 7.5 0.93 7.6 5.2 1.1 1 0 0 1 1 1 0 Transmembrane protein Sec10 PF07393.6 KLO17799.1 - 1 7.4 5.0 1.5 6.9 3.5 1.1 1 0 0 1 1 1 0 Exocyst complex component Sec10 SDA1 PF05285.7 KLO17799.1 - 2.9 7.0 21.1 0.019 14.2 5.6 2.2 2 0 0 2 2 2 0 SDA1 DUF1510 PF07423.6 KLO17800.1 - 0.039 13.3 0.0 0.039 13.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) DUF2077 PF09850.4 KLO17800.1 - 0.085 12.2 0.0 0.13 11.6 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2077) ICMT PF04140.9 KLO17801.1 - 5.5e-12 45.7 0.0 1.4e-11 44.4 0.0 1.6 2 0 0 2 2 2 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.8 KLO17801.1 - 1.9e-07 31.1 0.8 2.7e-07 30.6 0.1 1.7 2 0 0 2 2 2 1 Phospholipid methyltransferase ERG4_ERG24 PF01222.12 KLO17801.1 - 3e-05 22.7 0.0 7.7e-05 21.4 0.0 1.6 1 1 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family ICMT PF04140.9 KLO17802.1 - 2.5e-12 46.8 1.7 5.4e-12 45.7 0.0 2.3 3 1 0 3 3 3 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.8 KLO17802.1 - 6.8e-08 32.5 0.2 6.8e-08 32.5 0.1 2.4 2 1 1 3 3 3 1 Phospholipid methyltransferase ERG4_ERG24 PF01222.12 KLO17802.1 - 5.9e-07 28.3 0.4 9.6e-07 27.6 0.3 1.3 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family ICMT PF04140.9 KLO17803.1 - 3.7e-11 43.0 0.8 5.7e-11 42.4 0.0 1.7 2 0 0 2 2 2 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.8 KLO17803.1 - 2.1e-08 34.2 2.2 2.9e-08 33.7 0.1 2.1 2 1 0 2 2 2 1 Phospholipid methyltransferase ERG4_ERG24 PF01222.12 KLO17803.1 - 9.6e-05 21.0 0.0 0.00066 18.3 0.0 2.0 1 1 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family Sod_Fe_C PF02777.13 KLO17804.1 - 1.1e-33 115.1 0.1 2e-33 114.4 0.1 1.3 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.17 KLO17804.1 - 3.6e-32 110.4 3.8 4.3e-32 110.2 1.8 1.7 2 0 0 2 2 2 1 Iron/manganese superoxide dismutases, alpha-hairpin domain AAA PF00004.24 KLO17805.1 - 3e-12 46.8 0.0 1.1e-11 45.0 0.0 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 KLO17805.1 - 0.03 14.4 0.4 2.9 8.0 0.0 3.5 3 1 1 4 4 4 0 AAA domain ArgK PF03308.11 KLO17805.1 - 0.12 11.0 0.0 0.22 10.2 0.0 1.3 1 0 0 1 1 1 0 ArgK protein AAA_16 PF13191.1 KLO17805.1 - 0.23 11.4 3.0 0.56 10.1 0.2 3.1 2 1 1 3 3 3 0 AAA ATPase domain Sigma70_ner PF04546.8 KLO17805.1 - 0.78 9.3 7.8 1.6 8.3 5.4 1.4 1 0 0 1 1 1 0 Sigma-70, non-essential region p450 PF00067.17 KLO17806.1 - 8.6e-74 248.7 0.0 1.1e-73 248.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Bowman-Birk_leg PF00228.15 KLO17807.1 - 1.4 8.7 4.5 12 5.8 0.1 3.0 3 0 0 3 3 3 0 Bowman-Birk serine protease inhibitor family Death PF00531.17 KLO17808.1 - 0.14 11.9 0.0 0.3 10.8 0.0 1.5 1 0 0 1 1 1 0 Death domain zf-C2H2 PF00096.21 KLO17808.1 - 0.18 12.1 3.1 0.71 10.3 2.2 2.1 1 0 0 1 1 1 0 Zinc finger, C2H2 type Sgf11 PF08209.6 KLO17808.1 - 0.28 10.5 4.9 0.89 8.9 3.4 1.8 1 0 0 1 1 1 0 Sgf11 (transcriptional regulation protein) YhzD PF14120.1 KLO17809.1 - 0.079 12.8 0.9 0.21 11.5 0.6 1.8 1 0 0 1 1 1 0 YhzD-like protein Pol_alpha_B_N PF08418.5 KLO17809.1 - 4.2 6.8 13.2 10 5.5 9.2 1.6 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal FAM195 PF14799.1 KLO17810.1 - 0.033 14.0 0.1 1 9.2 0.0 2.1 1 1 1 2 2 2 0 FAM195 family DUF3328 PF11807.3 KLO17813.1 - 6e-16 58.7 0.5 2.1e-15 56.9 0.3 1.7 1 1 0 1 1 1 1 Domain of unknown function (DUF3328) DUF4117 PF13491.1 KLO17815.1 - 5.8 6.3 13.6 0.064 12.6 1.5 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4117) DUF3328 PF11807.3 KLO17816.1 - 5.6e-08 32.7 1.1 1.8e-07 31.0 0.1 2.0 1 1 1 2 2 2 1 Domain of unknown function (DUF3328) p450 PF00067.17 KLO17820.1 - 1.8e-63 214.6 0.0 2.1e-63 214.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Aldo_ket_red PF00248.16 KLO17822.1 - 2.2e-66 223.5 0.0 2.7e-66 223.2 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family RTA1 PF04479.8 KLO17823.1 - 1.9e-38 132.2 7.1 2.6e-38 131.7 4.9 1.1 1 0 0 1 1 1 1 RTA1 like protein DUF2208 PF09973.4 KLO17823.1 - 7 5.8 8.3 1.1 8.4 2.0 2.0 2 0 0 2 2 2 0 Predicted membrane protein (DUF2208) RTA1 PF04479.8 KLO17824.1 - 5.2e-36 124.2 6.4 8.7e-36 123.5 4.4 1.3 1 0 0 1 1 1 1 RTA1 like protein LRR19-TM PF15176.1 KLO17824.1 - 0.064 12.9 0.2 0.064 12.9 0.1 1.8 2 0 0 2 2 2 0 Leucine-rich repeat family 19 TM domain NfeD PF01957.13 KLO17824.1 - 0.76 9.9 8.9 2.6 8.1 0.1 3.3 2 1 1 3 3 3 0 NfeD-like C-terminal, partner-binding DUF3995 PF13160.1 KLO17824.1 - 2.3 8.2 12.7 1.2 9.2 2.7 3.3 2 2 2 4 4 4 0 Protein of unknown function (DUF3995) Ferritin_2 PF13668.1 KLO17825.1 - 4.8e-42 143.1 0.1 8.8e-42 142.3 0.1 1.3 1 0 0 1 1 1 1 Ferritin-like domain Peptidase_M16 PF00675.15 KLO17827.1 - 0.13 11.9 0.0 0.28 10.9 0.0 1.4 1 0 0 1 1 1 0 Insulinase (Peptidase family M16) DUF240 PF03086.9 KLO17829.1 - 0.13 11.9 0.0 0.23 11.1 0.0 1.3 1 0 0 1 1 1 0 MG032/MG096/MG288 family 2 RTA1 PF04479.8 KLO17830.1 - 1.7e-32 112.7 9.3 2.5e-32 112.2 6.4 1.1 1 0 0 1 1 1 1 RTA1 like protein Kei1 PF08552.6 KLO17830.1 - 0.029 14.0 0.3 0.071 12.7 0.2 1.7 1 1 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 p450 PF00067.17 KLO17831.1 - 8.3e-68 228.9 0.0 1e-67 228.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Glyco_transf_15 PF01793.11 KLO17832.1 - 9.3e-28 97.1 6.7 1.1e-27 96.9 4.6 1.2 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase NmrA PF05368.8 KLO17833.1 - 1.7e-34 119.1 0.0 2.2e-34 118.7 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 KLO17833.1 - 7e-11 42.4 0.2 1.2e-10 41.7 0.1 1.5 1 1 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 KLO17833.1 - 0.00031 19.5 0.0 0.00048 18.9 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 KLO17833.1 - 0.00049 19.5 0.0 0.0014 18.1 0.0 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Semialdhyde_dh PF01118.19 KLO17833.1 - 0.00094 19.4 0.0 0.0018 18.5 0.0 1.5 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain KR PF08659.5 KLO17833.1 - 0.0036 16.9 0.0 0.0059 16.2 0.0 1.3 1 0 0 1 1 1 1 KR domain adh_short PF00106.20 KLO17833.1 - 0.006 16.5 0.1 0.0093 15.8 0.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase NmrA PF05368.8 KLO17834.1 - 2.8e-33 115.1 0.0 4.2e-33 114.5 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 KLO17834.1 - 2.1e-11 44.1 0.1 8.4e-11 42.2 0.1 2.0 1 1 0 1 1 1 1 NADH(P)-binding adh_short PF00106.20 KLO17834.1 - 2.5e-05 24.2 0.1 4.1e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KLO17834.1 - 3e-05 23.7 0.0 4.9e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 KR domain Semialdhyde_dh PF01118.19 KLO17834.1 - 0.0018 18.5 0.0 0.0032 17.7 0.0 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain 3Beta_HSD PF01073.14 KLO17834.1 - 0.0033 16.1 0.0 0.0045 15.7 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family F420_oxidored PF03807.12 KLO17834.1 - 0.0036 17.6 0.0 0.015 15.7 0.0 2.0 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent Shikimate_DH PF01488.15 KLO17834.1 - 0.0049 16.9 0.0 0.016 15.3 0.0 1.8 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase NAD_binding_7 PF13241.1 KLO17834.1 - 0.013 15.7 0.0 0.031 14.5 0.0 1.6 1 0 0 1 1 1 0 Putative NAD(P)-binding Epimerase PF01370.16 KLO17834.1 - 0.022 14.2 0.0 0.033 13.6 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Ferritin_2 PF13668.1 KLO17835.1 - 4.2e-43 146.5 0.7 1.1e-42 145.2 0.3 1.8 3 0 0 3 3 3 1 Ferritin-like domain Rubrerythrin PF02915.12 KLO17835.1 - 0.031 14.5 0.0 0.12 12.7 0.0 2.0 1 1 0 1 1 1 0 Rubrerythrin Peptidase_C54 PF03416.14 KLO17837.1 - 3.7e-84 282.1 0.0 6e-84 281.4 0.0 1.3 1 0 0 1 1 1 1 Peptidase family C54 AMP-binding PF00501.23 KLO17840.1 - 8.5e-49 166.0 0.0 1.2e-48 165.5 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme TFX_C PF14601.1 KLO17840.1 - 0.0059 16.3 0.1 0.012 15.3 0.1 1.5 1 0 0 1 1 1 1 DNA_binding protein, TFX, C-term Acetyltransf_3 PF13302.1 KLO17841.1 - 1e-26 93.8 0.0 1.3e-26 93.5 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 KLO17841.1 - 2.5e-10 40.4 0.1 5.6e-10 39.3 0.1 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 KLO17841.1 - 2.6e-05 23.8 0.0 0.00016 21.3 0.0 2.0 1 1 0 1 1 1 1 FR47-like protein Acetyltransf_1 PF00583.19 KLO17841.1 - 4e-05 23.5 0.0 9.5e-05 22.3 0.0 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_4 PF13420.1 KLO17841.1 - 0.0046 16.9 0.7 0.034 14.0 0.5 2.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain PHA_gran_rgn PF09650.5 KLO17841.1 - 0.037 14.1 1.7 0.068 13.2 0.7 1.7 2 0 0 2 2 2 0 Putative polyhydroxyalkanoic acid system protein (PHA_gran_rgn) Acetyltransf_7 PF13508.1 KLO17841.1 - 0.14 12.3 0.0 0.24 11.6 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Ras PF00071.17 KLO17842.1 - 5.3e-38 129.9 0.0 8e-37 126.1 0.0 2.0 2 0 0 2 2 2 1 Ras family Miro PF08477.8 KLO17842.1 - 7.2e-17 61.9 0.0 1.2e-16 61.2 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KLO17842.1 - 1.4e-10 40.7 0.0 3.4e-10 39.4 0.0 1.6 2 0 0 2 2 2 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 KLO17842.1 - 3.1e-05 23.2 0.0 4.5e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 KLO17842.1 - 0.0007 19.5 0.0 0.0012 18.8 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 KLO17842.1 - 0.001 18.5 0.0 0.005 16.2 0.0 2.3 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_24 PF13479.1 KLO17842.1 - 0.043 13.3 0.2 0.082 12.4 0.2 1.4 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.1 KLO17842.1 - 0.067 13.3 0.0 0.14 12.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain PduV-EutP PF10662.4 KLO17842.1 - 0.08 12.4 0.0 0.4 10.1 0.0 2.1 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation DUF605 PF04652.11 KLO17842.1 - 0.71 9.2 16.6 0.95 8.7 11.5 1.2 1 0 0 1 1 1 0 Vta1 like DUF2422 PF10337.4 KLO17843.1 - 3.7e-55 187.5 3.0 3.5e-54 184.3 2.1 2.4 1 1 0 1 1 1 1 Protein of unknown function (DUF2422) DUF2421 PF10334.4 KLO17843.1 - 6.7e-53 179.6 0.0 1.1e-52 178.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2421) FUSC_2 PF13515.1 KLO17843.1 - 1.1e-07 31.7 15.4 1.1e-07 31.7 10.7 2.5 3 0 0 3 3 3 1 Fusaric acid resistance protein-like ALMT PF11744.3 KLO17843.1 - 0.00046 18.9 3.6 0.001 17.8 2.5 1.6 1 0 0 1 1 1 1 Aluminium activated malate transporter Pyr_redox_3 PF13738.1 KLO17844.1 - 6.5e-20 72.0 0.0 1.3e-19 71.1 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 KLO17844.1 - 1.3e-17 63.2 0.1 6.9e-16 57.5 0.0 2.7 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.1 KLO17844.1 - 3.3e-10 39.4 0.0 1.3e-06 27.5 0.0 3.0 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 KLO17844.1 - 1.2e-07 31.8 0.0 3.2e-06 27.1 0.0 2.3 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 KLO17844.1 - 2.4e-05 24.6 0.0 0.27 11.6 0.0 3.8 4 0 0 4 4 4 1 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.13 KLO17844.1 - 0.00013 21.6 0.3 0.11 12.1 0.0 2.3 2 0 0 2 2 2 2 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_binding_3 PF01494.14 KLO17844.1 - 0.00026 20.1 0.0 0.0034 16.4 0.0 2.3 3 0 0 3 3 3 1 FAD binding domain 2-Hacid_dh_C PF02826.14 KLO17844.1 - 0.00051 19.2 0.0 0.14 11.2 0.0 2.3 2 0 0 2 2 2 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_8 PF13450.1 KLO17844.1 - 0.00074 19.5 1.2 0.0083 16.1 0.0 3.0 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain GIDA PF01134.17 KLO17844.1 - 0.0013 17.6 0.2 0.052 12.4 0.0 2.7 3 0 0 3 3 3 1 Glucose inhibited division protein A DAO PF01266.19 KLO17844.1 - 0.0015 17.5 0.1 0.16 10.8 0.0 3.4 4 0 0 4 4 4 1 FAD dependent oxidoreductase HI0933_like PF03486.9 KLO17844.1 - 0.016 13.7 0.0 0.065 11.7 0.0 2.0 2 0 0 2 2 2 0 HI0933-like protein Thi4 PF01946.12 KLO17844.1 - 0.018 14.1 0.0 0.79 8.7 0.0 2.2 2 0 0 2 2 2 0 Thi4 family SnoaL_2 PF12680.2 KLO17844.1 - 0.02 15.2 0.0 0.057 13.8 0.0 1.8 1 0 0 1 1 1 0 SnoaL-like domain FAD_binding_2 PF00890.19 KLO17844.1 - 0.039 12.7 0.1 0.13 11.0 0.1 1.8 2 0 0 2 2 2 0 FAD binding domain NAD_binding_9 PF13454.1 KLO17844.1 - 0.15 11.8 0.2 4 7.1 0.1 2.6 2 1 0 2 2 2 0 FAD-NAD(P)-binding Acetyltransf_8 PF13523.1 KLO17845.1 - 6.1e-33 113.8 0.1 9.5e-33 113.2 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 KLO17845.1 - 0.0029 17.7 0.1 0.0065 16.6 0.1 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain DUF1643 PF07799.7 KLO17845.1 - 0.047 13.3 0.0 0.08 12.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1643) UPF0016 PF01169.14 KLO17846.1 - 4.7e-43 145.1 21.9 3.3e-22 78.4 5.7 2.1 2 0 0 2 2 2 2 Uncharacterized protein family UPF0016 TerC PF03741.11 KLO17846.1 - 0.0059 16.0 0.3 0.0059 16.0 0.2 2.4 2 1 0 2 2 2 1 Integral membrane protein TerC family YIEGIA PF14045.1 KLO17846.1 - 0.023 13.3 1.0 0.028 13.0 0.1 1.6 2 0 0 2 2 2 0 YIEGIA protein CitMHS PF03600.11 KLO17846.1 - 0.037 12.6 0.1 0.037 12.6 0.1 2.5 2 1 0 2 2 2 0 Citrate transporter DUF2208 PF09973.4 KLO17846.1 - 0.15 11.2 0.2 0.53 9.4 0.0 1.9 2 0 0 2 2 2 0 Predicted membrane protein (DUF2208) DUF204 PF02659.10 KLO17846.1 - 7.2 6.8 15.4 7.5 6.7 2.7 2.5 2 0 0 2 2 2 0 Domain of unknown function DUF Lactamase_B_2 PF12706.2 KLO17847.1 - 3.5e-18 65.8 0.2 8.2e-14 51.5 0.0 2.1 2 0 0 2 2 2 2 Beta-lactamase superfamily domain Lactamase_B PF00753.22 KLO17847.1 - 2.6e-07 30.4 0.0 8.6e-07 28.7 0.0 1.8 2 0 0 2 2 2 1 Metallo-beta-lactamase superfamily DUF2422 PF10337.4 KLO17848.1 - 2e-65 221.3 0.3 4.4e-65 220.2 0.2 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2422) DUF2421 PF10334.4 KLO17848.1 - 2.7e-54 184.2 0.0 5.8e-54 183.1 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2421) FUSC_2 PF13515.1 KLO17848.1 - 1.2e-08 34.9 9.5 1.2e-08 34.9 6.6 3.5 3 0 0 3 3 3 1 Fusaric acid resistance protein-like V-SNARE PF05008.10 KLO17852.1 - 1.2e-21 76.6 9.8 3e-21 75.3 2.6 2.3 2 0 0 2 2 2 1 Vesicle transport v-SNARE protein N-terminus V-SNARE_C PF12352.3 KLO17852.1 - 7.7e-16 57.9 4.7 7.7e-16 57.9 3.2 2.0 2 0 0 2 2 2 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.8 KLO17852.1 - 0.029 14.0 0.6 0.072 12.7 0.1 1.9 2 0 0 2 2 2 0 Sec20 YlqD PF11068.3 KLO17852.1 - 0.094 12.7 3.9 0.42 10.6 0.4 2.2 2 0 0 2 2 2 0 YlqD protein Fusion_gly PF00523.13 KLO17852.1 - 0.1 10.6 0.0 0.19 9.7 0.0 1.4 1 0 0 1 1 1 0 Fusion glycoprotein F0 Laminin_I PF06008.9 KLO17852.1 - 0.57 9.4 9.0 3.3 6.9 1.5 2.1 2 0 0 2 2 2 0 Laminin Domain I DUF1068 PF06364.7 KLO17852.1 - 0.71 9.4 3.4 1 8.9 1.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1068) Filament PF00038.16 KLO17852.1 - 0.83 9.0 10.9 0.2 11.1 3.2 2.2 2 1 0 2 2 2 0 Intermediate filament protein DUF883 PF05957.8 KLO17852.1 - 0.98 9.8 12.4 0.99 9.8 0.5 2.9 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF883) NPBW PF15180.1 KLO17852.1 - 2 8.0 7.3 3.8 7.1 0.1 3.1 1 1 1 3 3 3 0 Neuropeptides B and W COG2 PF06148.6 KLO17852.1 - 2.6 7.9 6.4 18 5.1 1.7 2.3 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF3619 PF12279.3 KLO17852.1 - 3 7.9 6.1 4.6 7.3 0.5 2.7 1 1 0 2 2 2 0 Protein of unknown function (DUF3619) YqjK PF13997.1 KLO17852.1 - 8.1 6.7 6.6 0.47 10.6 0.3 2.2 3 0 0 3 3 2 0 YqjK-like protein Prefoldin_2 PF01920.15 KLO17853.1 - 6.7e-21 74.0 11.1 8.3e-21 73.7 7.7 1.0 1 0 0 1 1 1 1 Prefoldin subunit FlaC_arch PF05377.6 KLO17853.1 - 0.04 13.8 0.5 0.04 13.8 0.3 2.3 2 1 0 2 2 2 0 Flagella accessory protein C (FlaC) CVNH PF08881.5 KLO17853.1 - 0.075 13.2 0.2 0.1 12.8 0.1 1.5 1 1 0 1 1 1 0 CVNH domain DUF4372 PF14294.1 KLO17853.1 - 0.12 12.2 0.0 0.21 11.4 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4372) YgaB PF14182.1 KLO17853.1 - 0.14 12.4 7.0 0.76 10.0 1.2 2.2 2 0 0 2 2 2 0 YgaB-like protein Tropomyosin PF00261.15 KLO17853.1 - 0.22 10.5 7.8 0.71 8.9 0.8 2.1 2 0 0 2 2 2 0 Tropomyosin Img2 PF05046.9 KLO17853.1 - 0.24 11.6 2.5 12 6.1 0.1 2.1 2 0 0 2 2 2 0 Mitochondrial large subunit ribosomal protein (Img2) Peptidase_S46 PF10459.4 KLO17853.1 - 0.26 9.6 4.3 0.29 9.4 3.0 1.0 1 0 0 1 1 1 0 Peptidase S46 IncA PF04156.9 KLO17853.1 - 0.42 10.1 11.7 2.8 7.5 8.1 1.9 1 1 0 1 1 1 0 IncA protein Orthopox_A5L PF06193.6 KLO17853.1 - 0.43 10.4 5.8 0.52 10.2 4.0 1.0 1 0 0 1 1 1 0 Orthopoxvirus A5L protein-like CENP-Q PF13094.1 KLO17853.1 - 0.45 10.5 8.5 13 5.7 4.9 2.1 1 1 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit DMPK_coil PF08826.5 KLO17853.1 - 0.45 10.4 7.5 1.3 8.9 0.6 2.5 2 1 0 2 2 2 0 DMPK coiled coil domain like Alb1 PF09135.6 KLO17853.1 - 0.52 10.9 4.8 5.9 7.5 3.3 2.1 1 1 0 1 1 1 0 Alb1 Occludin_ELL PF07303.8 KLO17853.1 - 0.63 10.8 5.3 1.2 9.9 0.5 2.0 1 1 0 2 2 2 0 Occludin homology domain ADIP PF11559.3 KLO17853.1 - 0.82 9.5 10.4 17 5.2 6.2 2.1 1 1 0 1 1 1 0 Afadin- and alpha -actinin-Binding Mnd1 PF03962.10 KLO17853.1 - 1.1 8.9 8.2 6.2 6.4 0.7 2.0 1 1 0 2 2 2 0 Mnd1 family Prefoldin PF02996.12 KLO17853.1 - 1.2 8.8 9.8 11 5.6 6.8 2.1 1 1 0 1 1 1 0 Prefoldin subunit Syntaxin_2 PF14523.1 KLO17853.1 - 1.7 8.7 7.2 8.2 6.5 1.1 2.1 2 0 0 2 2 2 0 Syntaxin-like protein DUF1409 PF07197.7 KLO17853.1 - 1.7 8.7 5.4 7.2 6.7 0.2 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF1409) AAA_23 PF13476.1 KLO17853.1 - 1.9 8.8 6.0 2.2 8.5 4.2 1.1 1 0 0 1 1 1 0 AAA domain Snf7 PF03357.16 KLO17853.1 - 2.6 7.3 9.9 0.67 9.3 1.6 2.0 1 1 1 2 2 2 0 Snf7 Atg14 PF10186.4 KLO17853.1 - 3.2 6.5 6.3 5.1 5.9 4.3 1.4 1 1 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 CENP-F_leu_zip PF10473.4 KLO17853.1 - 5.5 6.8 10.2 3.5 7.4 0.8 2.1 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Ribosomal_S17 PF00366.15 KLO17854.1 - 2.7e-13 49.7 0.4 3.3e-13 49.4 0.3 1.1 1 0 0 1 1 1 1 Ribosomal protein S17 DUF3490 PF11995.3 KLO17854.1 - 0.033 13.7 0.1 0.041 13.4 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3490) Vac_Fusion PF02346.11 KLO17854.1 - 0.061 12.7 0.0 0.1 12.0 0.0 1.3 1 0 0 1 1 1 0 Chordopoxvirus fusion protein zf-CCHC_4 PF14392.1 KLO17859.1 - 0.19 11.4 1.5 2.4 7.9 0.9 2.4 2 0 0 2 2 2 0 Zinc knuckle Fasciclin PF02469.17 KLO17860.1 - 1.6e-34 118.6 9.0 6.5e-23 81.1 1.0 2.2 2 0 0 2 2 2 2 Fasciclin domain LRR_8 PF13855.1 KLO17862.1 - 0.023 14.4 1.9 0.15 11.8 0.0 3.1 3 0 0 3 3 3 0 Leucine rich repeat Mpv17_PMP22 PF04117.7 KLO17863.1 - 4e-23 80.8 1.1 7.9e-23 79.8 0.8 1.5 1 0 0 1 1 1 1 Mpv17 / PMP22 family Fasciclin PF02469.17 KLO17864.1 - 5e-32 110.5 0.1 1.7e-23 83.0 0.0 2.2 2 0 0 2 2 2 2 Fasciclin domain AsnC_trans_reg PF01037.16 KLO17869.1 - 0.15 11.7 0.1 0.31 10.7 0.1 1.6 1 0 0 1 1 1 0 AsnC family MAGP PF05507.6 KLO17870.1 - 0.22 11.3 0.7 0.42 10.4 0.5 1.4 1 0 0 1 1 1 0 Microfibril-associated glycoprotein (MAGP) Telethonin PF09470.5 KLO17881.1 - 0.15 11.5 0.0 0.24 10.8 0.0 1.2 1 0 0 1 1 1 0 Telethonin protein Helicase_RecD PF05127.9 KLO17882.1 - 0.061 12.9 0.0 0.62 9.6 0.0 2.1 2 0 0 2 2 2 0 Helicase Grp1_Fun34_YaaH PF01184.14 KLO17883.1 - 2.4e-74 249.1 16.5 3e-74 248.8 11.4 1.0 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family DUF373 PF04123.8 KLO17883.1 - 0.0084 15.1 4.0 0.011 14.7 2.8 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF373) PP1_bind PF15276.1 KLO17884.1 - 0.041 13.9 0.0 0.11 12.5 0.0 1.6 1 0 0 1 1 1 0 Protein phosphatase 1 binding HSCB_C PF07743.8 KLO17890.1 - 0.014 15.8 0.3 0.027 14.9 0.2 1.5 1 0 0 1 1 1 0 HSCB C-terminal oligomerisation domain Sipho_Gp157 PF05565.6 KLO17890.1 - 0.016 14.7 0.1 0.02 14.4 0.1 1.2 1 0 0 1 1 1 0 Siphovirus Gp157 Vac_Fusion PF02346.11 KLO17890.1 - 0.042 13.2 0.1 0.076 12.4 0.1 1.4 1 0 0 1 1 1 0 Chordopoxvirus fusion protein DALR_1 PF05746.10 KLO17890.1 - 0.24 11.3 1.2 2.6 8.0 0.8 2.0 1 1 0 1 1 1 0 DALR anticodon binding domain tRNA-synt_2b PF00587.20 KLO17893.1 - 3.9e-65 218.6 0.1 6.7e-65 217.8 0.1 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 KLO17893.1 - 1.9e-20 72.6 0.0 4.8e-20 71.2 0.0 1.8 1 0 0 1 1 1 1 Anticodon binding domain Transaldolase PF00923.14 KLO17894.1 - 7.3e-94 314.1 0.0 8.3e-94 313.9 0.0 1.0 1 0 0 1 1 1 1 Transaldolase Glyco_hydro_12 PF01670.11 KLO17895.1 - 1.2e-27 96.6 2.8 1.2e-27 96.6 2.0 1.7 2 1 0 2 2 2 1 Glycosyl hydrolase family 12 Ribosomal_L24e PF01246.15 KLO17896.1 - 1.1e-29 102.0 0.2 1.1e-29 102.0 0.1 2.0 2 0 0 2 2 2 1 Ribosomal protein L24e TerB-C PF15615.1 KLO17896.1 - 0.2 11.9 3.8 0.27 11.4 2.7 1.1 1 0 0 1 1 1 0 TerB-C domain Ribosomal_60s PF00428.14 KLO17896.1 - 0.21 12.0 4.4 0.3 11.4 3.1 1.3 1 0 0 1 1 1 0 60s Acidic ribosomal protein Synaptobrevin PF00957.16 KLO17897.1 - 7.1e-25 86.4 0.8 8.9e-25 86.1 0.5 1.1 1 0 0 1 1 1 1 Synaptobrevin DUF2976 PF11190.3 KLO17897.1 - 0.023 14.1 0.8 0.036 13.5 0.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2976) DUF1634 PF07843.6 KLO17897.1 - 0.03 13.9 0.1 0.042 13.4 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1634) Prominin PF05478.6 KLO17897.1 - 0.13 9.7 0.0 0.16 9.5 0.0 1.0 1 0 0 1 1 1 0 Prominin SKG6 PF08693.5 KLO17898.1 - 0.00013 21.2 0.2 0.00028 20.1 0.1 1.6 1 0 0 1 1 1 1 Transmembrane alpha-helix domain SprB PF13573.1 KLO17898.1 - 0.00058 19.4 1.2 0.0021 17.6 0.8 2.0 1 0 0 1 1 1 1 SprB repeat Podoplanin PF05808.6 KLO17898.1 - 0.0045 16.5 0.3 0.012 15.2 0.1 1.8 2 0 0 2 2 2 1 Podoplanin MAP65_ASE1 PF03999.7 KLO17899.1 - 6.7e-60 203.3 22.9 2.8e-57 194.7 9.8 2.5 2 1 0 2 2 2 2 Microtubule associated protein (MAP65/ASE1 family) DUF4111 PF13427.1 KLO17899.1 - 0.17 11.6 1.6 2.5 7.9 0.1 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4111) FliJ PF02050.11 KLO17899.1 - 0.6 10.1 10.8 0.07 13.1 0.5 3.2 2 1 1 3 3 3 0 Flagellar FliJ protein Pkinase PF00069.20 KLO17900.1 - 1.6e-73 247.0 0.0 3.1e-73 246.1 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KLO17900.1 - 3.6e-39 134.4 0.0 5.2e-39 133.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KLO17900.1 - 2.3e-09 36.6 0.0 3.5e-09 36.0 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 KLO17900.1 - 0.011 14.7 0.1 0.022 13.7 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF1744 PF08490.7 KLO17901.1 - 8.2e-107 357.1 0.0 1.3e-106 356.5 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1744) DNA_pol_B_exo1 PF03104.14 KLO17901.1 - 1.6e-51 175.1 0.0 3e-51 174.2 0.0 1.5 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain DNA_pol_B PF00136.16 KLO17901.1 - 4.3e-20 71.9 0.0 4.1e-19 68.7 0.0 2.5 2 1 0 2 2 2 1 DNA polymerase family B DNA_pol_B_exo2 PF10108.4 KLO17901.1 - 5.5e-08 32.6 0.3 6.4e-07 29.1 0.1 2.6 2 1 0 2 2 2 1 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB RNase_H_2 PF13482.1 KLO17901.1 - 0.0001 22.1 0.0 0.00046 20.0 0.0 2.1 1 0 0 1 1 1 1 RNase_H superfamily Skp1_POZ PF03931.10 KLO17902.1 - 1.9e-07 31.0 0.0 4e-07 30.0 0.0 1.6 2 0 0 2 2 2 1 Skp1 family, tetramerisation domain Pkinase_Tyr PF07714.12 KLO17904.1 - 4.8e-39 133.9 0.0 6.8e-39 133.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 KLO17904.1 - 6.8e-37 127.0 0.0 8.5e-37 126.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.1 KLO17904.1 - 0.003 16.5 0.0 0.0046 15.9 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 KLO17904.1 - 0.042 13.5 0.0 0.084 12.5 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family RIO1 PF01163.17 KLO17904.1 - 0.065 12.5 0.0 0.11 11.7 0.0 1.4 1 0 0 1 1 1 0 RIO1 family WH1 PF00568.18 KLO17905.1 - 7.1e-24 83.6 0.0 9.8e-24 83.2 0.0 1.2 1 0 0 1 1 1 1 WH1 domain PBD PF00786.23 KLO17905.1 - 4.9e-07 30.0 0.3 4.9e-07 30.0 0.2 1.9 2 0 0 2 2 2 1 P21-Rho-binding domain WH2 PF02205.15 KLO17905.1 - 0.0025 17.3 0.0 0.007 15.9 0.0 1.8 1 0 0 1 1 1 1 WH2 motif Glyco_hydro_11 PF00457.12 KLO17906.1 - 2.5e-79 264.9 18.8 3.1e-79 264.5 13.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 11 CBM_1 PF00734.13 KLO17906.1 - 6e-11 41.7 10.1 1.9e-10 40.2 7.0 1.9 1 0 0 1 1 1 1 Fungal cellulose binding domain Histone PF00125.19 KLO17907.1 - 3.8e-14 52.5 0.1 4.5e-14 52.3 0.1 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TAF PF02969.12 KLO17907.1 - 4.1e-05 23.4 0.1 5.8e-05 22.9 0.1 1.4 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CENP-S PF15630.1 KLO17907.1 - 4.4e-05 23.5 0.0 5.7e-05 23.2 0.0 1.3 1 1 0 1 1 1 1 Kinetochore component CENP-S CBFD_NFYB_HMF PF00808.18 KLO17907.1 - 0.00061 19.8 0.2 0.0012 18.8 0.1 1.6 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-T PF15511.1 KLO17907.1 - 0.044 13.0 0.0 0.044 13.0 0.0 1.1 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T TFIID-31kDa PF02291.10 KLO17907.1 - 0.069 12.9 0.0 0.089 12.5 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.8 KLO17907.1 - 0.078 12.7 0.0 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 Bromodomain associated Histone PF00125.19 KLO17908.1 - 6.6e-30 103.0 0.7 1e-29 102.4 0.5 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 KLO17908.1 - 2.4e-05 24.4 0.0 3.8e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 Kinetochore component CENP-S CBFD_NFYB_HMF PF00808.18 KLO17908.1 - 0.0032 17.4 0.1 0.0059 16.6 0.1 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-T PF15511.1 KLO17908.1 - 0.0085 15.3 1.2 0.0097 15.1 0.9 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T Bromo_TP PF07524.8 KLO17908.1 - 0.087 12.5 0.1 0.14 11.8 0.1 1.4 1 0 0 1 1 1 0 Bromodomain associated F-box-like PF12937.2 KLO17909.1 - 1.8e-07 30.7 0.9 1.8e-07 30.7 0.6 2.5 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 KLO17909.1 - 0.0016 18.0 0.4 0.0016 18.0 0.3 2.5 2 0 0 2 2 2 1 F-box domain YkuI_C PF10388.4 KLO17909.1 - 0.14 11.8 0.5 0.25 10.9 0.3 1.3 1 0 0 1 1 1 0 EAL-domain associated signalling protein domain RhoGAP PF00620.22 KLO17910.1 - 7.1e-47 158.8 0.0 1.3e-46 157.9 0.0 1.4 1 0 0 1 1 1 1 RhoGAP domain FCH PF00611.18 KLO17910.1 - 4.9e-14 52.2 2.1 1.3e-13 50.8 0.0 2.3 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain NUP50 PF08911.6 KLO17910.1 - 0.04 14.3 2.0 0.13 12.6 1.4 1.9 1 0 0 1 1 1 0 NUP50 (Nucleoporin 50 kDa) ATP-synt_ab PF00006.20 KLO17910.1 - 0.041 13.3 0.4 7.6 5.9 0.0 2.6 2 1 1 3 3 3 0 ATP synthase alpha/beta family, nucleotide-binding domain DUF745 PF05335.8 KLO17910.1 - 0.076 12.5 4.7 0.16 11.4 3.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF745) DivIC PF04977.10 KLO17910.1 - 2.3 7.7 6.3 2.2 7.8 3.1 1.9 2 0 0 2 2 2 0 Septum formation initiator Nucleopor_Nup85 PF07575.8 KLO17911.1 - 3e-53 180.9 0.0 6.1e-34 117.1 0.0 2.1 2 0 0 2 2 2 2 Nup85 Nucleoporin Opi1 PF08618.5 KLO17912.1 - 1.4e-69 235.1 9.4 1.8e-61 208.3 1.1 3.5 2 1 2 4 4 4 2 Transcription factor Opi1 Perilipin PF03036.11 KLO17912.1 - 4.1e-05 22.5 0.1 0.00012 21.0 0.0 1.8 2 0 0 2 2 2 1 Perilipin family GATA PF00320.22 KLO17913.1 - 2.9e-30 103.3 15.7 2.8e-15 55.3 3.6 2.6 2 0 0 2 2 2 2 GATA zinc finger TF_Zn_Ribbon PF08271.7 KLO17913.1 - 2e-05 23.8 3.2 0.061 12.6 0.4 2.8 2 0 0 2 2 2 2 TFIIB zinc-binding RRN7 PF11781.3 KLO17913.1 - 0.065 12.7 4.5 2.2 7.8 0.4 2.6 2 0 0 2 2 2 0 RNA polymerase I-specific transcription initiation factor Rrn7 Auto_anti-p27 PF06677.7 KLO17913.1 - 0.29 10.9 3.3 3.6 7.4 0.3 2.5 2 0 0 2 2 2 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) eIF-5_eIF-2B PF01873.12 KLO17913.1 - 3.6 7.2 5.6 4 7.1 0.3 2.3 2 0 0 2 2 2 0 Domain found in IF2B/IF5 Pneumo_phosprot PF02478.11 KLO17914.1 - 0.044 13.3 0.3 0.044 13.3 0.2 2.4 2 0 0 2 2 2 0 Pneumovirus phosphoprotein RhoGEF PF00621.15 KLO17914.1 - 0.052 13.4 0.0 0.089 12.6 0.0 1.3 1 0 0 1 1 1 0 RhoGEF domain DUF2130 PF09903.4 KLO17914.1 - 0.054 12.2 2.1 0.21 10.2 0.1 2.1 1 1 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2130) Lipase_2 PF01674.13 KLO17914.1 - 0.071 12.4 0.2 0.16 11.2 0.1 1.5 1 0 0 1 1 1 0 Lipase (class 2) Ferritin PF00210.19 KLO17914.1 - 0.12 12.1 0.3 0.22 11.2 0.2 1.3 1 0 0 1 1 1 0 Ferritin-like domain Muted PF14942.1 KLO17914.1 - 0.88 9.4 5.2 0.38 10.6 0.1 2.5 2 0 0 2 2 2 0 Organelle biogenesis, Muted-like protein Methyltransf_16 PF10294.4 KLO17915.1 - 3.8e-27 94.8 0.0 5.6e-27 94.3 0.0 1.2 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_23 PF13489.1 KLO17915.1 - 0.015 15.0 0.0 0.028 14.1 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_18 PF12847.2 KLO17915.1 - 0.02 15.4 0.0 0.051 14.1 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.7 KLO17915.1 - 0.031 14.7 0.0 0.069 13.6 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain MTS PF05175.9 KLO17915.1 - 0.16 11.3 0.0 0.32 10.3 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase small domain Rhomboid PF01694.17 KLO17916.1 - 9e-15 54.9 10.2 6.9e-14 52.0 7.1 2.2 1 1 0 1 1 1 1 Rhomboid family ECH_C PF13766.1 KLO17916.1 - 0.045 13.8 0.2 0.087 12.9 0.1 1.4 1 0 0 1 1 1 0 2-enoyl-CoA Hydratase C-terminal region Methyltransf_16 PF10294.4 KLO17917.1 - 3.4e-16 59.1 0.0 1.6e-14 53.7 0.0 2.3 1 1 0 1 1 1 1 Putative methyltransferase Methyltransf_18 PF12847.2 KLO17917.1 - 0.0023 18.4 0.0 0.0046 17.5 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KLO17917.1 - 0.0053 16.4 0.0 0.0066 16.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain RrnaAD PF00398.15 KLO17917.1 - 0.0069 15.4 0.0 0.012 14.6 0.0 1.3 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase PCMT PF01135.14 KLO17917.1 - 0.11 11.9 0.0 0.16 11.4 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MTS PF05175.9 KLO17917.1 - 0.13 11.6 0.0 0.24 10.7 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain Asp PF00026.18 KLO17919.1 - 9.2e-75 251.8 3.0 1.1e-74 251.5 2.1 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 KLO17919.1 - 5.2e-08 33.0 1.6 3e-07 30.5 0.5 2.5 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal TAXi_C PF14541.1 KLO17919.1 - 0.0067 15.9 0.1 0.026 14.0 0.1 1.9 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal Histone PF00125.19 KLO17920.1 - 6.6e-30 103.0 0.7 1e-29 102.4 0.5 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 KLO17920.1 - 2.4e-05 24.4 0.0 3.8e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 Kinetochore component CENP-S CBFD_NFYB_HMF PF00808.18 KLO17920.1 - 0.0032 17.4 0.1 0.0059 16.6 0.1 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-T PF15511.1 KLO17920.1 - 0.0085 15.3 1.2 0.0097 15.1 0.9 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T Bromo_TP PF07524.8 KLO17920.1 - 0.087 12.5 0.1 0.14 11.8 0.1 1.4 1 0 0 1 1 1 0 Bromodomain associated Histone PF00125.19 KLO17921.1 - 3.8e-14 52.5 0.1 4.5e-14 52.3 0.1 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TAF PF02969.12 KLO17921.1 - 4.1e-05 23.4 0.1 5.8e-05 22.9 0.1 1.4 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CENP-S PF15630.1 KLO17921.1 - 4.4e-05 23.5 0.0 5.7e-05 23.2 0.0 1.3 1 1 0 1 1 1 1 Kinetochore component CENP-S CBFD_NFYB_HMF PF00808.18 KLO17921.1 - 0.00061 19.8 0.2 0.0012 18.8 0.1 1.6 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-T PF15511.1 KLO17921.1 - 0.044 13.0 0.0 0.044 13.0 0.0 1.1 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T TFIID-31kDa PF02291.10 KLO17921.1 - 0.069 12.9 0.0 0.089 12.5 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.8 KLO17921.1 - 0.078 12.7 0.0 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 Bromodomain associated p450 PF00067.17 KLO17922.1 - 3.8e-57 193.8 0.0 5e-57 193.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 DUF3129 PF11327.3 KLO17923.1 - 1.7e-52 177.9 16.0 1.9e-52 177.7 11.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3129) I-set PF07679.11 KLO17923.1 - 0.035 13.9 0.0 0.057 13.2 0.0 1.3 1 0 0 1 1 1 0 Immunoglobulin I-set domain DUF4137 PF13593.1 KLO17924.1 - 0.0076 15.3 1.9 0.013 14.6 0.9 1.7 1 1 1 2 2 2 1 SBF-like CPA transporter family (DUF4137) DUF2015 PF09435.5 KLO17925.1 - 2.3e-36 124.4 0.0 2.5e-36 124.2 0.0 1.0 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF2015) Amnionless PF14828.1 KLO17925.1 - 0.078 11.4 0.0 0.088 11.2 0.0 1.0 1 0 0 1 1 1 0 Amnionless Smr PF01713.16 KLO17926.1 - 1.9e-10 40.7 0.0 4.6e-10 39.5 0.0 1.7 1 0 0 1 1 1 1 Smr domain DUF1771 PF08590.5 KLO17926.1 - 0.0036 17.2 2.5 0.0088 16.0 1.8 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1771) Virul_fac_BrkB PF03631.10 KLO17927.1 - 0.00043 19.7 0.6 0.00059 19.2 0.4 1.2 1 0 0 1 1 1 1 Virulence factor BrkB Bacillus_HBL PF05791.6 KLO17927.1 - 0.024 14.0 0.0 0.039 13.3 0.0 1.2 1 0 0 1 1 1 0 Bacillus haemolytic enterotoxin (HBL) DUF4229 PF14012.1 KLO17927.1 - 0.43 10.5 2.8 1.1 9.1 2.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF4229) DUF98 PF01947.11 KLO17928.1 - 0.0013 18.5 0.0 0.0017 18.1 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF98) zf-C2HC5 PF06221.8 KLO17929.1 - 1.3e-12 47.2 4.6 2e-12 46.6 3.2 1.3 1 0 0 1 1 1 1 Putative zinc finger motif, C2HC5-type DUF3510 PF12022.3 KLO17930.1 - 0.014 15.5 0.0 0.03 14.4 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3510) adh_short_C2 PF13561.1 KLO17932.1 - 2.4e-26 92.9 0.0 2.8e-26 92.7 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 KLO17932.1 - 4.1e-25 88.6 0.0 5.3e-25 88.2 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KLO17932.1 - 2e-09 37.3 0.0 2.8e-09 36.9 0.0 1.1 1 0 0 1 1 1 1 KR domain Eno-Rase_NADH_b PF12242.3 KLO17932.1 - 0.0004 20.1 0.1 0.00085 19.0 0.0 1.5 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase DUF1776 PF08643.5 KLO17932.1 - 0.023 13.8 0.0 0.029 13.4 0.0 1.1 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) THF_DHG_CYH_C PF02882.14 KLO17932.1 - 0.079 12.0 0.0 0.16 11.0 0.0 1.5 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain RhoGAP PF00620.22 KLO17933.1 - 6.5e-43 145.9 0.0 1.1e-42 145.1 0.0 1.4 1 0 0 1 1 1 1 RhoGAP domain PH PF00169.24 KLO17933.1 - 4.9e-13 49.1 0.0 1e-12 48.1 0.0 1.6 1 0 0 1 1 1 1 PH domain PX PF00787.19 KLO17933.1 - 4.1e-08 32.9 0.0 1e-07 31.7 0.0 1.7 1 0 0 1 1 1 1 PX domain PH_11 PF15413.1 KLO17933.1 - 3.5e-07 30.4 0.0 1.1e-06 28.8 0.0 2.0 1 0 0 1 1 1 1 Pleckstrin homology domain PH_8 PF15409.1 KLO17933.1 - 0.0073 16.3 0.0 0.026 14.5 0.0 1.9 2 0 0 2 2 2 1 Pleckstrin homology domain SDH_alpha PF03313.10 KLO17934.1 - 3.8e-91 305.0 0.4 5.4e-91 304.5 0.3 1.1 1 0 0 1 1 1 1 Serine dehydratase alpha chain SDH_beta PF03315.10 KLO17934.1 - 9.6e-56 188.2 0.0 1.7e-55 187.4 0.0 1.4 1 0 0 1 1 1 1 Serine dehydratase beta chain Ras PF00071.17 KLO17935.1 - 4.9e-51 172.3 0.0 6.2e-51 172.0 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KLO17935.1 - 2.5e-14 53.7 0.0 3.4e-14 53.3 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KLO17935.1 - 1.4e-06 27.6 0.0 1.8e-06 27.3 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 KLO17935.1 - 0.0047 16.0 0.0 0.0056 15.8 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 KLO17935.1 - 0.011 15.7 0.0 0.015 15.2 0.0 1.3 1 0 0 1 1 1 0 50S ribosome-binding GTPase SRPRB PF09439.5 KLO17935.1 - 0.021 14.0 0.0 0.03 13.5 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit Sugar_tr PF00083.19 KLO17936.1 - 1.3e-123 412.9 26.1 1.5e-123 412.7 18.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KLO17936.1 - 4.1e-22 78.3 45.8 2.1e-20 72.7 18.8 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily F-box-like PF12937.2 KLO17938.1 - 0.00096 18.8 4.9 0.0051 16.5 3.4 2.4 1 1 0 1 1 1 1 F-box-like DEAD PF00270.24 KLO17940.1 - 6.9e-41 139.5 0.0 6.2e-40 136.4 0.0 2.5 3 0 0 3 3 3 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KLO17940.1 - 1.8e-22 78.9 0.0 6.1e-22 77.2 0.0 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Helicase_C_2 PF13307.1 KLO17940.1 - 0.0017 18.3 0.1 0.0092 15.9 0.0 2.2 2 1 0 2 2 2 1 Helicase C-terminal domain DUF2608 PF11019.3 KLO17940.1 - 0.0033 16.4 1.2 0.0047 15.9 0.1 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF2608) DUF1253 PF06862.7 KLO17940.1 - 0.014 13.8 0.2 0.2 10.0 0.0 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF1253) Clathrin PF00637.15 KLO17941.1 - 1.8e-209 685.7 36.4 1.8e-33 115.1 3.2 7.4 7 0 0 7 7 7 7 Region in Clathrin and VPS Clathrin_H_link PF13838.1 KLO17941.1 - 3.9e-29 100.3 0.7 9.6e-29 99.0 0.1 2.1 2 0 0 2 2 2 1 Clathrin-H-link Clathrin_propel PF01394.15 KLO17941.1 - 8.5e-29 97.8 2.8 0.00017 21.6 0.0 7.7 7 0 0 7 7 7 6 Clathrin propeller repeat Clathrin-link PF09268.5 KLO17941.1 - 4.8e-11 41.4 0.8 1.5e-10 39.8 0.0 2.4 2 0 0 2 2 2 1 Clathrin, heavy-chain linker TPR_1 PF00515.23 KLO17941.1 - 0.0061 16.1 0.8 43 3.9 0.1 5.2 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_12 PF13424.1 KLO17941.1 - 0.026 14.4 7.7 0.42 10.5 0.1 5.2 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_7 PF13176.1 KLO17941.1 - 0.076 12.8 5.5 16 5.5 0.1 5.1 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_10 PF13374.1 KLO17941.1 - 0.092 12.7 3.9 11 6.0 0.2 4.6 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_19 PF14559.1 KLO17941.1 - 0.095 13.0 6.3 20 5.5 0.1 5.8 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_2 PF07719.12 KLO17941.1 - 0.16 11.9 8.2 59 3.9 0.0 6.3 6 0 0 6 6 6 0 Tetratricopeptide repeat PQ-loop PF04193.9 KLO17942.1 - 2.4e-16 58.9 11.4 5.6e-13 48.2 1.8 2.7 3 0 0 3 3 3 2 PQ loop repeat ubiquitin PF00240.18 KLO17943.1 - 4.8e-34 115.5 0.8 1e-33 114.5 0.6 1.5 1 0 0 1 1 1 1 Ubiquitin family Ribosomal_S27 PF01599.14 KLO17943.1 - 5.4e-26 90.1 1.5 1.1e-25 89.1 1.0 1.6 1 0 0 1 1 1 1 Ribosomal protein S27a Rad60-SLD PF11976.3 KLO17943.1 - 3.6e-19 68.2 0.6 7.4e-19 67.2 0.4 1.5 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 KLO17943.1 - 1.1e-05 25.5 0.7 6.6e-05 23.0 0.1 2.4 2 1 0 2 2 2 1 Ubiquitin-like domain Telomere_Sde2 PF13019.1 KLO17943.1 - 8.7e-05 22.2 0.0 0.00014 21.5 0.0 1.3 1 0 0 1 1 1 1 Telomere stability and silencing DUF2407 PF10302.4 KLO17943.1 - 0.0037 17.4 0.5 0.005 16.9 0.4 1.3 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain Rad60-SLD_2 PF13881.1 KLO17943.1 - 0.0045 16.8 0.5 0.01 15.7 0.3 1.6 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like IBR PF01485.16 KLO17943.1 - 0.0059 16.4 0.7 0.0088 15.8 0.5 1.3 1 0 0 1 1 1 1 IBR domain zf-CGNR PF11706.3 KLO17943.1 - 0.04 13.4 0.7 0.074 12.5 0.5 1.4 1 0 0 1 1 1 0 CGNR zinc finger zf-C2H2_3 PF13878.1 KLO17943.1 - 0.052 13.1 0.2 0.11 12.1 0.1 1.5 1 0 0 1 1 1 0 zinc-finger of acetyl-transferase ESCO Plexin_cytopl PF08337.7 KLO17943.1 - 0.069 11.4 0.8 5.1 5.2 0.0 2.0 2 0 0 2 2 2 0 Plexin cytoplasmic RasGAP domain DUF2870 PF11069.3 KLO17943.1 - 0.13 12.3 0.9 0.23 11.5 0.2 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2870) AAA PF00004.24 KLO17944.1 - 9.6e-18 64.6 0.0 1.5e-17 64.0 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rep_fac_C PF08542.6 KLO17944.1 - 3.9e-17 62.0 0.0 1.2e-16 60.4 0.0 1.9 1 0 0 1 1 1 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.1 KLO17944.1 - 4.2e-16 59.0 0.0 4.2e-14 52.5 0.0 2.2 1 1 0 1 1 1 1 DNA polymerase III, delta subunit Rad17 PF03215.10 KLO17944.1 - 3.8e-10 39.0 0.0 1.5e-08 33.7 0.0 2.4 1 1 1 2 2 2 1 Rad17 cell cycle checkpoint protein AAA_14 PF13173.1 KLO17944.1 - 3.4e-07 30.1 0.1 9.3e-07 28.8 0.0 1.7 1 1 1 2 2 2 1 AAA domain AAA_22 PF13401.1 KLO17944.1 - 9.8e-07 28.9 0.6 0.00082 19.5 0.4 2.6 1 1 0 1 1 1 1 AAA domain DUF815 PF05673.8 KLO17944.1 - 2.5e-06 26.6 0.0 3.7e-06 26.0 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_19 PF13245.1 KLO17944.1 - 7.7e-06 25.5 0.0 1.8e-05 24.4 0.0 1.5 1 0 0 1 1 1 1 Part of AAA domain AAA_11 PF13086.1 KLO17944.1 - 1.1e-05 25.2 0.2 9.3e-05 22.1 0.2 2.3 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.7 KLO17944.1 - 2.8e-05 23.3 0.0 5.3e-05 22.3 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 KLO17944.1 - 5.1e-05 23.3 0.0 0.00062 19.7 0.0 2.0 1 1 1 2 2 2 1 AAA ATPase domain DNA_pol3_delta PF06144.8 KLO17944.1 - 8.4e-05 22.1 0.0 0.00016 21.2 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA_30 PF13604.1 KLO17944.1 - 0.00022 20.8 0.2 0.0031 17.1 0.1 2.4 2 1 0 2 2 1 1 AAA domain AAA_5 PF07728.9 KLO17944.1 - 0.00027 20.7 0.2 0.0032 17.1 0.0 2.8 3 1 0 3 3 2 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 KLO17944.1 - 0.00035 20.1 0.0 0.00067 19.2 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DEAD PF00270.24 KLO17944.1 - 0.0015 18.0 0.1 0.034 13.6 0.0 2.1 1 1 1 2 2 2 1 DEAD/DEAH box helicase Arch_ATPase PF01637.13 KLO17944.1 - 0.0042 16.8 0.1 0.0074 16.0 0.0 1.3 1 0 0 1 1 1 1 Archaeal ATPase AAA_25 PF13481.1 KLO17944.1 - 0.0057 16.0 0.1 0.034 13.5 0.0 2.3 2 1 0 2 2 2 1 AAA domain IstB_IS21 PF01695.12 KLO17944.1 - 0.0076 15.6 0.0 0.015 14.6 0.0 1.5 1 1 0 1 1 1 1 IstB-like ATP binding protein Viral_helicase1 PF01443.13 KLO17944.1 - 0.011 15.2 0.0 0.018 14.5 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase ResIII PF04851.10 KLO17944.1 - 0.011 15.5 0.1 0.099 12.4 0.0 2.0 1 1 1 2 2 2 0 Type III restriction enzyme, res subunit AAA_24 PF13479.1 KLO17944.1 - 0.016 14.7 0.2 0.031 13.8 0.1 1.5 1 1 0 1 1 1 0 AAA domain AAA_17 PF13207.1 KLO17944.1 - 0.031 15.0 0.0 0.082 13.7 0.0 1.7 2 0 0 2 2 1 0 AAA domain T2SE PF00437.15 KLO17944.1 - 0.036 12.9 0.0 0.067 12.0 0.0 1.5 1 1 0 1 1 1 0 Type II/IV secretion system protein Methyltransf_31 PF13847.1 KLO17944.1 - 0.036 13.6 0.0 0.062 12.8 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain AAA_10 PF12846.2 KLO17944.1 - 0.039 13.3 0.2 4.1 6.7 0.0 2.2 1 1 0 2 2 2 0 AAA-like domain AAA_28 PF13521.1 KLO17944.1 - 0.039 13.9 0.1 0.088 12.7 0.0 1.6 1 1 0 1 1 1 0 AAA domain Mg_chelatase PF01078.16 KLO17944.1 - 0.061 12.4 0.0 0.34 10.0 0.0 2.0 1 1 0 2 2 2 0 Magnesium chelatase, subunit ChlI PIF1 PF05970.9 KLO17944.1 - 0.062 12.2 0.1 1.5 7.7 0.1 2.1 1 1 1 2 2 2 0 PIF1-like helicase SNF2_N PF00176.18 KLO17944.1 - 0.065 12.0 0.0 0.33 9.7 0.0 1.8 1 1 0 2 2 2 0 SNF2 family N-terminal domain DUF2075 PF09848.4 KLO17944.1 - 0.085 11.8 0.0 0.22 10.4 0.0 1.6 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) MobB PF03205.9 KLO17944.1 - 0.098 12.3 0.0 0.22 11.2 0.0 1.7 1 1 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Zw10 PF06248.8 KLO17945.1 - 2.4e-30 105.2 0.2 5.4e-24 84.2 0.0 2.7 3 1 0 3 3 3 2 Centromere/kinetochore Zw10 Dsl1_C PF11989.3 KLO17945.1 - 9.4e-08 31.5 0.8 7.1e-07 28.6 0.0 2.5 2 0 0 2 2 2 1 Retrograde transport protein Dsl1 C terminal CcdA PF07362.7 KLO17945.1 - 1.4 8.8 5.1 0.96 9.3 0.0 3.0 3 0 0 3 3 3 0 Post-segregation antitoxin CcdA TPR_16 PF13432.1 KLO17946.1 - 5.4e-08 33.3 1.3 0.0036 17.9 0.0 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_19 PF14559.1 KLO17946.1 - 1.7e-07 31.5 2.7 0.0053 17.0 0.6 2.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.1 KLO17946.1 - 1.1e-06 28.1 0.0 0.0056 16.3 0.0 2.5 1 1 1 2 2 2 2 TPR repeat TPR_15 PF13429.1 KLO17946.1 - 0.00087 18.4 1.1 0.0091 15.0 0.4 2.3 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.1 KLO17946.1 - 0.0017 18.8 4.4 3.1 8.7 0.2 4.6 3 2 2 5 5 5 1 Tetratricopeptide repeat TPR_12 PF13424.1 KLO17946.1 - 0.0072 16.2 0.5 2.8 7.9 0.1 2.8 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.12 KLO17946.1 - 0.012 15.4 0.0 8.2 6.6 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.1 KLO17946.1 - 0.13 12.1 0.1 20 5.2 0.0 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat MBOAT PF03062.14 KLO17947.1 - 6.5e-33 114.2 14.7 3.7e-32 111.7 10.1 2.1 1 1 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family MBOAT_2 PF13813.1 KLO17947.1 - 0.0024 17.9 4.4 0.003 17.5 1.4 2.3 2 0 0 2 2 2 1 Membrane bound O-acyl transferase family RED_N PF07808.8 KLO17948.1 - 3.5e-15 55.8 7.5 3.5e-15 55.8 5.2 2.8 3 1 0 3 3 3 1 RED-like protein N-terminal region MMgT PF10270.4 KLO17949.1 - 3.4e-17 62.7 0.0 3.8e-17 62.6 0.0 1.0 1 0 0 1 1 1 1 Membrane magnesium transporter UPF0197 PF05251.7 KLO17949.1 - 0.047 13.9 0.1 0.068 13.4 0.1 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0197) DUF1624 PF07786.7 KLO17949.1 - 0.074 12.3 0.0 0.083 12.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1624) DUF2484 PF10658.4 KLO17951.1 - 0.096 12.8 0.5 0.096 12.8 0.3 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF2484) SKG6 PF08693.5 KLO17951.1 - 0.27 10.5 2.6 0.93 8.8 1.8 2.0 1 0 0 1 1 1 0 Transmembrane alpha-helix domain TRAUB PF08164.7 KLO17952.1 - 4.5e-27 93.9 1.8 8.4e-27 93.1 0.0 2.4 3 0 0 3 3 3 1 Apoptosis-antagonizing transcription factor, C-terminal AATF-Che1 PF13339.1 KLO17952.1 - 1.9e-19 70.1 0.2 1.9e-19 70.1 0.2 2.7 3 1 0 3 3 3 1 Apoptosis antagonizing transcription factor NIR_SIR PF01077.17 KLO17954.1 - 1.2e-49 167.6 0.0 1.6e-44 150.9 0.0 2.5 2 0 0 2 2 2 2 Nitrite and sulphite reductase 4Fe-4S domain NIR_SIR_ferr PF03460.12 KLO17954.1 - 3.8e-30 103.3 0.1 8.3e-16 57.3 0.0 2.5 2 0 0 2 2 2 2 Nitrite/Sulfite reductase ferredoxin-like half domain Flavodoxin_1 PF00258.20 KLO17954.1 - 1.1e-25 90.2 0.0 2.1e-25 89.4 0.0 1.5 1 0 0 1 1 1 1 Flavodoxin POR_N PF01855.14 KLO17954.1 - 0.0011 18.5 0.0 0.0021 17.5 0.0 1.4 1 0 0 1 1 1 1 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg Flavodoxin_5 PF12724.2 KLO17954.1 - 0.0098 15.8 0.0 0.029 14.3 0.0 1.8 1 0 0 1 1 1 1 Flavodoxin domain DUF4515 PF14988.1 KLO17955.1 - 0.0066 16.1 0.0 0.0075 15.9 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4515) LOH1CR12 PF10158.4 KLO17955.1 - 0.064 13.0 0.0 0.071 12.8 0.0 1.1 1 0 0 1 1 1 0 Tumour suppressor protein adh_short PF00106.20 KLO17956.1 - 7.8e-22 77.9 6.6 3.4e-15 56.3 0.2 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.1 KLO17956.1 - 1.1e-20 74.4 0.4 8.1e-12 45.4 0.1 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KLO17956.1 - 2.8e-08 33.6 0.5 1.7e-07 31.0 0.1 2.1 2 1 0 2 2 2 1 KR domain NAD_binding_10 PF13460.1 KLO17956.1 - 0.0028 17.6 0.2 0.0066 16.4 0.1 1.6 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 KLO17956.1 - 0.0037 16.7 0.2 0.012 15.0 0.0 1.8 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family Pyr_redox PF00070.22 KLO17956.1 - 0.037 14.4 0.2 0.13 12.7 0.1 2.0 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.13 KLO17956.1 - 0.11 12.1 0.1 0.33 10.5 0.1 1.7 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Clr2 PF10383.4 KLO17957.1 - 3.8e-05 23.7 0.0 0.00018 21.5 0.0 2.0 1 1 0 1 1 1 1 Transcription-silencing protein Clr2 KAR9 PF08580.5 KLO17958.1 - 7.4e-09 34.4 0.4 7.4e-09 34.4 0.3 3.8 3 1 1 4 4 4 2 Yeast cortical protein KAR9 GAS2 PF02187.12 KLO17958.1 - 0.00095 18.8 0.0 0.0018 17.9 0.0 1.4 1 0 0 1 1 1 1 Growth-Arrest-Specific Protein 2 Domain DUF1515 PF07439.6 KLO17958.1 - 0.31 10.8 2.1 0.39 10.5 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1515) Pex14_N PF04695.8 KLO17959.1 - 2 8.4 9.2 2.7 8.0 6.4 1.3 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF605 PF04652.11 KLO17959.1 - 2.3 7.5 10.5 2.6 7.3 7.3 1.0 1 0 0 1 1 1 0 Vta1 like PX PF00787.19 KLO17960.1 - 8.2e-20 70.6 0.0 2.2e-19 69.3 0.0 1.7 1 0 0 1 1 1 1 PX domain Vps5 PF09325.5 KLO17960.1 - 1.5e-08 34.2 2.3 0.00099 18.4 0.3 2.1 2 0 0 2 2 2 2 Vps5 C terminal like GreA_GreB_N PF03449.10 KLO17960.1 - 0.04 13.9 1.8 0.84 9.7 0.2 2.7 2 0 0 2 2 2 0 Transcription elongation factor, N-terminal DUF626 PF04776.7 KLO17960.1 - 0.061 13.6 0.4 4.5 7.6 0.3 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF626) AAA_33 PF13671.1 KLO17961.1 - 3.4e-14 52.9 0.0 1.6e-13 50.7 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 KLO17961.1 - 4.3e-06 27.5 0.0 6.1e-06 27.0 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 KLO17961.1 - 0.0005 20.3 0.0 0.00079 19.7 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 KLO17961.1 - 0.00062 19.7 0.0 0.001 19.0 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain tRNA_lig_kinase PF08303.6 KLO17961.1 - 0.0013 18.6 0.0 0.0019 18.1 0.0 1.3 1 0 0 1 1 1 1 tRNA ligase kinase domain Zeta_toxin PF06414.7 KLO17961.1 - 0.0067 15.5 0.0 0.015 14.4 0.0 1.5 1 1 0 1 1 1 1 Zeta toxin KTI12 PF08433.5 KLO17961.1 - 0.016 14.4 0.0 0.066 12.4 0.0 1.7 1 1 1 2 2 2 0 Chromatin associated protein KTI12 AAA_14 PF13173.1 KLO17961.1 - 0.018 14.9 0.0 0.029 14.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain APS_kinase PF01583.15 KLO17961.1 - 0.042 13.5 0.0 0.063 12.9 0.0 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase UPF0079 PF02367.12 KLO17961.1 - 0.046 13.3 0.0 0.078 12.6 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 AAA_22 PF13401.1 KLO17961.1 - 0.054 13.6 0.0 0.094 12.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain ATP_bind_1 PF03029.12 KLO17961.1 - 0.087 12.3 0.0 0.14 11.6 0.0 1.2 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein Mg_chelatase PF01078.16 KLO17961.1 - 0.13 11.4 0.0 0.23 10.5 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_29 PF13555.1 KLO17961.1 - 0.13 11.7 0.0 0.25 10.9 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain TPR_11 PF13414.1 KLO17962.1 - 1.7e-22 78.7 1.1 1.2e-10 40.8 0.0 3.2 2 1 1 3 3 3 3 TPR repeat TPR_1 PF00515.23 KLO17962.1 - 2.3e-15 55.4 0.2 8.6e-07 28.3 0.0 5.5 5 1 0 5 5 5 2 Tetratricopeptide repeat TPR_2 PF07719.12 KLO17962.1 - 8.6e-15 53.3 1.2 2e-06 27.2 0.0 5.3 4 1 2 6 6 6 2 Tetratricopeptide repeat TPR_16 PF13432.1 KLO17962.1 - 5.5e-14 52.3 0.3 3.4e-07 30.7 0.0 2.7 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_17 PF13431.1 KLO17962.1 - 1.7e-13 49.5 0.4 0.0075 16.3 0.0 3.9 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_12 PF13424.1 KLO17962.1 - 2.8e-13 49.6 1.9 3.1e-05 23.8 0.1 3.3 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_14 PF13428.1 KLO17962.1 - 1.7e-12 46.7 1.4 5.3e-05 23.4 0.0 4.4 2 2 2 4 4 4 3 Tetratricopeptide repeat TPR_19 PF14559.1 KLO17962.1 - 1.7e-10 41.0 0.3 0.00039 20.7 0.1 2.6 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.1 KLO17962.1 - 1.5e-07 30.7 1.9 0.019 14.7 0.0 4.2 3 2 1 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.1 KLO17962.1 - 2.9e-07 29.7 0.1 0.037 13.8 0.0 5.1 4 1 2 6 6 6 1 Tetratricopeptide repeat TPR_15 PF13429.1 KLO17962.1 - 1.5e-05 24.2 0.0 1.9e-05 23.8 0.0 1.2 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_9 PF13371.1 KLO17962.1 - 1.9e-05 24.3 0.2 0.024 14.4 0.0 2.4 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_6 PF13174.1 KLO17962.1 - 3.2e-05 24.1 0.2 0.027 14.9 0.0 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat Apc3 PF12895.2 KLO17962.1 - 9.5e-05 22.4 0.1 0.12 12.5 0.0 2.5 2 1 0 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_4 PF07721.9 KLO17962.1 - 0.00021 21.3 1.0 0.19 12.2 0.0 3.9 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_10 PF13374.1 KLO17962.1 - 0.00035 20.4 3.0 4.9 7.2 0.0 3.9 3 1 1 4 4 4 2 Tetratricopeptide repeat MIT PF04212.13 KLO17962.1 - 0.0028 17.4 1.1 0.44 10.4 0.1 3.2 2 1 1 3 3 3 1 MIT (microtubule interacting and transport) domain TPR_20 PF14561.1 KLO17962.1 - 0.0067 16.5 0.2 0.13 12.4 0.0 2.4 1 1 1 2 2 2 1 Tetratricopeptide repeat DUF3856 PF12968.2 KLO17962.1 - 0.0071 16.1 0.3 0.6 9.9 0.2 2.5 1 1 0 1 1 1 1 Domain of Unknown Function (DUF3856) Apc5 PF12862.2 KLO17962.1 - 0.031 14.1 0.0 0.06 13.1 0.0 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 5 Fis1_TPR_C PF14853.1 KLO17962.1 - 0.031 14.1 0.0 0.11 12.4 0.0 1.8 2 0 0 2 2 2 0 Fis1 C-terminal tetratricopeptide repeat Velvet PF11754.3 KLO17963.1 - 2.3e-28 99.2 0.0 5.1e-28 98.0 0.0 1.5 1 1 0 1 1 1 1 Velvet factor Cytochrom_C1 PF02167.10 KLO17964.1 - 4.8e-85 284.6 0.0 5.9e-85 284.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome C1 family Cytochrome_CBB3 PF13442.1 KLO17964.1 - 0.00047 20.2 0.0 0.00092 19.3 0.0 1.6 1 0 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C PF00034.16 KLO17964.1 - 0.01 16.6 0.3 0.027 15.2 0.1 1.9 2 1 0 2 2 2 0 Cytochrome c SAC3_GANP PF03399.11 KLO17965.1 - 4.9e-60 202.5 3.8 4.9e-60 202.5 2.7 2.1 2 0 0 2 2 2 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family PCI_Csn8 PF10075.4 KLO17965.1 - 3.6e-11 43.0 0.5 8.7e-11 41.7 0.3 1.6 1 0 0 1 1 1 1 COP9 signalosome, subunit CSN8 Myco_haema PF05692.7 KLO17965.1 - 0.00095 17.9 0.0 0.0014 17.4 0.0 1.2 1 0 0 1 1 1 1 Mycoplasma haemagglutinin tRNA_int_endo PF01974.12 KLO17966.1 - 2.5e-19 68.8 0.3 7.1e-19 67.3 0.2 1.8 1 1 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain tRNA_int_endo_N PF02778.9 KLO17966.1 - 1e-05 24.9 0.1 0.0017 17.8 0.1 2.4 2 0 0 2 2 2 2 tRNA intron endonuclease, N-terminal domain WD40 PF00400.27 KLO17967.1 - 4.4e-20 70.7 6.6 2.7e-07 30.2 0.0 6.3 5 1 0 5 5 5 5 WD domain, G-beta repeat PQQ_3 PF13570.1 KLO17967.1 - 0.084 13.1 0.3 18 5.7 0.1 3.6 3 0 0 3 3 3 0 PQQ-like domain Rrn6 PF10214.4 KLO17967.1 - 0.12 10.4 0.6 0.28 9.2 0.0 1.7 2 0 0 2 2 2 0 RNA polymerase I-specific transcription-initiation factor Fib_alpha PF08702.5 KLO17967.1 - 3.4 7.8 5.9 0.68 10.0 1.7 1.6 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family Aminotran_5 PF00266.14 KLO17968.1 - 1.2e-28 99.9 0.0 1.6e-28 99.5 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.15 KLO17968.1 - 0.00031 19.1 0.1 0.00049 18.5 0.1 1.4 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme B12-binding PF02310.14 KLO17968.1 - 0.00066 19.5 0.0 0.0014 18.4 0.0 1.5 1 0 0 1 1 1 1 B12 binding domain Amidase PF01425.16 KLO17969.1 - 1.5e-99 333.8 0.0 1.8e-99 333.6 0.0 1.0 1 0 0 1 1 1 1 Amidase RRM_1 PF00076.17 KLO17970.1 - 3e-32 110.0 1.8 5.7e-16 57.9 0.0 5.2 5 0 0 5 5 5 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KLO17970.1 - 1e-23 83.0 0.1 2.3e-08 33.8 0.0 4.2 3 1 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KLO17970.1 - 8.5e-17 60.7 0.0 5e-05 23.0 0.0 3.7 4 0 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) MIP-T3 PF10243.4 KLO17970.1 - 1.8 6.9 6.4 2.4 6.5 4.5 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 NIR_SIR PF01077.17 KLO17971.1 - 8e-50 168.2 0.1 1.1e-43 148.3 0.0 2.6 3 0 0 3 3 3 2 Nitrite and sulphite reductase 4Fe-4S domain NIR_SIR_ferr PF03460.12 KLO17971.1 - 1.8e-31 107.5 0.0 6.8e-17 60.8 0.0 2.5 2 0 0 2 2 2 2 Nitrite/Sulfite reductase ferredoxin-like half domain Flavodoxin_1 PF00258.20 KLO17971.1 - 1e-26 93.6 0.1 2e-26 92.7 0.1 1.5 1 0 0 1 1 1 1 Flavodoxin Flavodoxin_5 PF12724.2 KLO17971.1 - 0.00058 19.8 0.0 0.0013 18.7 0.0 1.6 1 0 0 1 1 1 1 Flavodoxin domain POR_N PF01855.14 KLO17971.1 - 0.0072 15.8 0.0 0.012 15.0 0.0 1.3 1 0 0 1 1 1 1 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg Peripla_BP_6 PF13458.1 KLO17971.1 - 0.046 13.0 0.1 0.12 11.7 0.1 1.6 1 0 0 1 1 1 0 Periplasmic binding protein DUF1903 PF08991.5 KLO17972.1 - 2e-06 27.8 1.7 2.6e-06 27.5 1.2 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1903) CHCH PF06747.8 KLO17972.1 - 0.00015 21.5 4.5 0.00023 21.0 3.2 1.3 1 0 0 1 1 1 1 CHCH domain UPF0203 PF05254.7 KLO17972.1 - 0.0023 17.7 3.9 0.0085 15.9 2.7 1.9 1 1 0 1 1 1 1 Uncharacterised protein family (UPF0203) Pet191_N PF10203.4 KLO17972.1 - 0.01 15.8 3.4 0.021 14.8 2.4 1.5 1 0 0 1 1 1 0 Cytochrome c oxidase assembly protein PET191 Pkinase PF00069.20 KLO17973.1 - 7.3e-72 241.6 0.0 1.1e-71 241.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KLO17973.1 - 2e-30 105.7 0.0 7.6e-30 103.8 0.0 1.9 3 0 0 3 3 3 1 Protein tyrosine kinase APH PF01636.18 KLO17973.1 - 0.0096 15.6 0.1 0.016 14.9 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.1 KLO17973.1 - 0.13 11.2 0.1 0.36 9.7 0.0 1.7 2 0 0 2 2 2 0 Kinase-like Acetyltransf_2 PF00797.12 KLO17974.1 - 5.3e-20 72.0 0.0 1.4e-18 67.3 0.0 2.1 1 1 0 1 1 1 1 N-acetyltransferase DUF3035 PF11233.3 KLO17974.1 - 0.076 13.0 0.5 0.13 12.2 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3035) zf-RanBP PF00641.13 KLO17977.1 - 1e-11 43.7 25.6 0.00023 20.2 1.4 3.5 3 0 0 3 3 3 3 Zn-finger in Ran binding protein and others zf-Sec23_Sec24 PF04810.10 KLO17977.1 - 0.00079 18.9 6.8 0.48 10.0 0.0 3.7 3 0 0 3 3 3 2 Sec23/Sec24 zinc finger DUF3615 PF12274.3 KLO17977.1 - 9.4 6.6 11.0 12 6.2 0.3 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3615) NADH-u_ox-rdase PF10785.4 KLO17978.1 - 2.4e-32 111.0 1.1 3.3e-32 110.5 0.7 1.2 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase complex I, 21 kDa subunit NADH_u_ox_C PF12853.2 KLO17978.1 - 1.2e-16 60.2 0.0 1.7e-16 59.6 0.0 1.3 1 0 0 1 1 1 1 C-terminal of NADH-ubiquinone oxidoreductase 21 kDa subunit DnaJ PF00226.26 KLO17979.1 - 3.4e-17 61.9 0.1 9.2e-17 60.5 0.0 1.8 1 0 0 1 1 1 1 DnaJ domain DnaJ PF00226.26 KLO17980.1 - 1.9e-21 75.5 1.0 3e-21 74.8 0.7 1.3 1 0 0 1 1 1 1 DnaJ domain Mito_fiss_reg PF05308.6 KLO17980.1 - 0.047 13.0 0.5 0.12 11.7 0.4 1.6 1 0 0 1 1 1 0 Mitochondrial fission regulator WD40 PF00400.27 KLO17981.1 - 2.2e-10 40.0 7.5 0.00045 20.0 0.6 5.0 5 0 0 5 5 5 3 WD domain, G-beta repeat Lzipper-MIP1 PF14389.1 KLO17981.1 - 0.049 13.7 0.1 0.097 12.7 0.1 1.5 1 0 0 1 1 1 0 Leucine-zipper of ternary complex factor MIP1 DUF1192 PF06698.6 KLO17981.1 - 0.061 13.1 0.3 0.15 11.9 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1192) Fungal_trans PF04082.13 KLO17982.1 - 5.9e-17 61.3 0.1 1.2e-16 60.4 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KLO17982.1 - 2.2e-05 24.2 10.0 4.5e-05 23.2 6.9 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Matrilin_ccoil PF10393.4 KLO17982.1 - 0.03 13.6 0.4 0.066 12.5 0.3 1.5 1 0 0 1 1 1 0 Trimeric coiled-coil oligomerisation domain of matrilin SH3_1 PF00018.23 KLO17983.1 - 1e-17 63.2 3.2 2.2e-08 33.3 0.2 2.9 2 1 0 2 2 2 2 SH3 domain SAM_2 PF07647.12 KLO17983.1 - 6.4e-15 54.7 0.0 1.3e-14 53.7 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SH3_9 PF14604.1 KLO17983.1 - 1.2e-13 50.4 3.0 7.8e-07 28.5 0.3 2.7 2 0 0 2 2 2 2 Variant SH3 domain SAM_1 PF00536.25 KLO17983.1 - 3e-13 49.7 0.0 6.3e-13 48.6 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) RA PF00788.18 KLO17983.1 - 1.2e-12 48.1 0.0 2.3e-12 47.2 0.0 1.4 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain SH3_2 PF07653.12 KLO17983.1 - 7.2e-12 44.6 0.5 3.4e-08 32.8 0.1 2.6 2 0 0 2 2 2 2 Variant SH3 domain SH3_3 PF08239.6 KLO17983.1 - 0.032 14.4 3.2 1.8 8.8 0.2 2.7 2 0 0 2 2 2 0 Bacterial SH3 domain zf-C4H2 PF10146.4 KLO17983.1 - 0.64 10.0 4.9 0.24 11.3 1.3 1.8 2 0 0 2 2 2 0 Zinc finger-containing protein Dus PF01207.12 KLO17984.1 - 7.5e-73 245.0 0.0 8.3e-73 244.9 0.0 1.2 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) ThiG PF05690.9 KLO17984.1 - 0.00067 18.8 0.0 0.0011 18.1 0.0 1.2 1 0 0 1 1 1 1 Thiazole biosynthesis protein ThiG SOR_SNZ PF01680.12 KLO17984.1 - 0.01 15.4 0.1 0.11 12.0 0.0 2.2 1 1 1 2 2 2 0 SOR/SNZ family His_biosynth PF00977.16 KLO17984.1 - 0.026 13.7 0.0 0.042 13.1 0.0 1.2 1 0 0 1 1 1 0 Histidine biosynthesis protein Abhydrolase_4 PF08386.5 KLO17986.1 - 1.2e-18 66.9 0.0 2.1e-18 66.1 0.0 1.4 1 0 0 1 1 1 1 TAP-like protein Abhydrolase_1 PF00561.15 KLO17986.1 - 2e-14 53.7 0.0 4.3e-14 52.6 0.0 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 KLO17986.1 - 6.8e-10 39.2 0.0 4.2e-09 36.6 0.0 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KLO17986.1 - 3.1e-06 26.9 0.0 9e-05 22.2 0.0 2.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_4 PF08386.5 KLO17987.1 - 1.3e-16 60.3 0.0 2.8e-16 59.2 0.0 1.6 1 0 0 1 1 1 1 TAP-like protein Abhydrolase_1 PF00561.15 KLO17987.1 - 2e-12 47.1 0.0 3.5e-12 46.3 0.0 1.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 KLO17987.1 - 3e-09 37.0 0.0 9.9e-09 35.4 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KLO17987.1 - 3.7e-05 23.5 0.0 0.00034 20.3 0.0 2.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family PITH PF06201.8 KLO17988.1 - 6.7e-40 136.3 0.4 7.7e-40 136.1 0.2 1.0 1 0 0 1 1 1 1 PITH domain TSGA13 PF14994.1 KLO17988.1 - 0.077 12.1 0.0 0.1 11.7 0.0 1.2 1 0 0 1 1 1 0 Testis-specific gene 13 protein RTC4 PF14474.1 KLO17991.1 - 2.4e-22 79.1 0.0 3e-22 78.8 0.0 1.1 1 0 0 1 1 1 1 RTC4-like domain ANTAR PF03861.9 KLO17991.1 - 0.049 13.2 0.0 0.12 11.9 0.0 1.6 1 0 0 1 1 1 0 ANTAR domain PTS_2-RNA PF01885.11 KLO17992.1 - 9.1e-61 204.4 0.1 1.3e-60 203.9 0.1 1.2 1 0 0 1 1 1 1 RNA 2'-phosphotransferase, Tpt1 / KptA family NinB PF05772.7 KLO17992.1 - 0.092 12.3 0.0 0.15 11.7 0.0 1.3 1 0 0 1 1 1 0 NinB protein zf-C3HC4_2 PF13923.1 KLO17993.1 - 1.9e-08 34.1 4.8 4.6e-08 32.9 3.4 1.7 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KLO17993.1 - 9.1e-08 31.6 4.9 1.7e-07 30.8 3.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KLO17993.1 - 1.2e-07 31.4 7.4 2.3e-07 30.5 5.2 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 KLO17993.1 - 1.7e-07 30.8 6.0 3.9e-07 29.6 4.1 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.20 KLO17993.1 - 2.8e-07 30.0 2.7 7.5e-07 28.7 1.9 1.7 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 KLO17993.1 - 2.6e-06 27.1 1.9 2.6e-06 27.1 1.3 2.0 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 KLO17993.1 - 3e-06 26.8 0.7 6.9e-06 25.6 0.5 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_6 PF14835.1 KLO17993.1 - 0.002 17.8 0.3 0.002 17.8 0.2 1.7 2 0 0 2 2 2 1 zf-RING of BARD1-type protein IncA PF04156.9 KLO17993.1 - 2.4 7.7 8.8 4.2 6.9 6.1 1.4 1 0 0 1 1 1 0 IncA protein Prok-RING_4 PF14447.1 KLO17993.1 - 3.2 7.3 9.6 0.17 11.4 1.0 2.4 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 RINGv PF12906.2 KLO17994.1 - 1.4e-15 57.0 7.5 2.3e-15 56.3 5.2 1.4 1 0 0 1 1 1 1 RING-variant domain zf-Apc11 PF12861.2 KLO17994.1 - 0.011 15.5 5.2 0.02 14.7 3.6 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_2 PF13639.1 KLO17994.1 - 0.56 10.0 8.5 0.93 9.3 5.9 1.4 1 0 0 1 1 1 0 Ring finger domain zf-RING-like PF08746.6 KLO17994.1 - 8.8 6.4 7.4 16 5.5 5.1 1.4 1 0 0 1 1 1 0 RING-like domain Arginosuc_synth PF00764.14 KLO17995.1 - 2.9e-156 520.4 0.0 3.4e-156 520.1 0.0 1.0 1 0 0 1 1 1 1 Arginosuccinate synthase QueC PF06508.8 KLO17995.1 - 0.00026 20.3 0.0 0.00042 19.6 0.0 1.3 1 0 0 1 1 1 1 Queuosine biosynthesis protein QueC Asn_synthase PF00733.16 KLO17995.1 - 0.0014 18.1 0.0 0.002 17.6 0.0 1.2 1 0 0 1 1 1 1 Asparagine synthase tRNA_Me_trans PF03054.11 KLO17995.1 - 0.006 15.1 0.0 0.0093 14.5 0.0 1.3 1 0 0 1 1 1 1 tRNA methyl transferase Pro-kuma_activ PF09286.6 KLO17997.1 - 2.6e-36 124.7 0.0 1.1e-35 122.8 0.1 2.0 3 0 0 3 3 3 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.17 KLO17997.1 - 2.5e-09 36.7 1.8 4.2e-09 35.9 1.3 1.3 1 0 0 1 1 1 1 Subtilase family zf-TFIIIC PF12660.2 KLO17998.1 - 2e-22 78.9 0.1 5.9e-22 77.4 0.1 1.8 1 0 0 1 1 1 1 Putative zinc-finger of transcription factor IIIC complex TFIIIC_delta PF12657.2 KLO17998.1 - 1e-19 70.8 3.2 1e-19 70.8 2.2 2.2 2 1 1 3 3 3 1 Transcription factor IIIC subunit delta N-term WD40 PF00400.27 KLO17998.1 - 0.031 14.1 1.6 8.1 6.5 0.2 3.8 3 0 0 3 3 3 0 WD domain, G-beta repeat DUF2457 PF10446.4 KLO17999.1 - 0.016 13.9 15.0 0.023 13.4 10.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) CENP-T PF15511.1 KLO17999.1 - 0.031 13.5 7.8 0.037 13.2 5.4 1.2 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T Pox_Ag35 PF03286.9 KLO17999.1 - 0.041 13.3 6.1 0.067 12.7 4.2 1.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Cwf_Cwc_15 PF04889.7 KLO17999.1 - 0.24 11.0 11.4 0.33 10.6 7.9 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein BUD22 PF09073.5 KLO17999.1 - 0.35 9.8 10.1 0.42 9.6 7.0 1.1 1 0 0 1 1 1 0 BUD22 CDC45 PF02724.9 KLO17999.1 - 1.2 7.1 11.4 1.4 6.8 7.9 1.1 1 0 0 1 1 1 0 CDC45-like protein PPP4R2 PF09184.6 KLO17999.1 - 1.3 8.4 13.8 1.9 7.9 9.6 1.2 1 0 0 1 1 1 0 PPP4R2 Osteopontin PF00865.13 KLO17999.1 - 2.3 7.3 17.9 2.8 7.0 12.4 1.1 1 0 0 1 1 1 0 Osteopontin NOA36 PF06524.7 KLO17999.1 - 6.1 6.0 16.0 7.5 5.7 11.1 1.1 1 0 0 1 1 1 0 NOA36 protein Nop14 PF04147.7 KLO17999.1 - 7.5 4.3 19.0 8.7 4.1 13.1 1.0 1 0 0 1 1 1 0 Nop14-like family Daxx PF03344.10 KLO17999.1 - 7.7 4.8 19.1 9.1 4.6 13.3 1.0 1 0 0 1 1 1 0 Daxx Family FimP PF09766.4 KLO17999.1 - 9.1 5.2 7.7 12 4.8 5.3 1.1 1 0 0 1 1 1 0 Fms-interacting protein TFIIA PF03153.8 KLO17999.1 - 9.8 5.9 18.6 14 5.4 12.9 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit ECR1_N PF14382.1 KLO18000.1 - 1.7e-15 55.9 0.1 3e-15 55.1 0.1 1.4 1 0 0 1 1 1 1 Exosome complex exonuclease RRP4 N-terminal region EXOSC1 PF10447.4 KLO18000.1 - 0.0035 17.2 0.0 0.16 11.9 0.0 2.6 1 1 0 1 1 1 1 Exosome component EXOSC1/CSL4 zf-MYND PF01753.13 KLO18001.1 - 4.4e-06 26.4 19.1 4.4e-06 26.4 13.2 2.2 3 0 0 3 3 3 1 MYND finger MRP-L20 PF12824.2 KLO18001.1 - 0.03 14.3 0.8 0.054 13.4 0.6 1.4 1 0 0 1 1 1 0 Mitochondrial ribosomal protein subunit L20 zf-Mss51 PF13824.1 KLO18001.1 - 3.9 7.4 14.6 24 4.9 10.1 2.3 1 1 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 RRM_1 PF00076.17 KLO18002.1 - 1.6e-14 53.2 0.1 3.1e-14 52.3 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KLO18002.1 - 3.4e-12 46.1 0.0 5.8e-12 45.4 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KLO18002.1 - 2.1e-09 37.0 0.0 3.9e-09 36.2 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 KLO18002.1 - 0.052 13.3 0.0 0.084 12.7 0.0 1.3 1 0 0 1 1 1 0 RNA binding motif HMA PF00403.21 KLO18002.1 - 0.096 12.8 0.0 0.14 12.3 0.0 1.3 1 0 0 1 1 1 0 Heavy-metal-associated domain YoaP PF14268.1 KLO18002.1 - 0.1 11.8 0.0 0.16 11.2 0.0 1.2 1 0 0 1 1 1 0 YoaP-like Chromo PF00385.19 KLO18003.1 - 7e-11 41.6 0.9 7e-11 41.6 0.6 2.3 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain Chromo_shadow PF01393.14 KLO18003.1 - 1.7e-05 24.5 0.1 6.8e-05 22.6 0.0 2.2 2 0 0 2 2 2 1 Chromo shadow domain DUF4551 PF15087.1 KLO18003.1 - 0.31 9.3 8.3 0.45 8.8 5.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) SOBP PF15279.1 KLO18003.1 - 1.4 9.2 9.9 2.3 8.5 6.9 1.3 1 0 0 1 1 1 0 Sine oculis-binding protein zf-MYND PF01753.13 KLO18004.1 - 1.2e-08 34.7 13.5 2e-08 33.9 9.3 1.4 1 0 0 1 1 1 1 MYND finger zf-HIT PF04438.11 KLO18004.1 - 2 8.1 6.9 5.3 6.7 4.8 1.8 1 0 0 1 1 1 0 HIT zinc finger Ecl1 PF12855.2 KLO18004.1 - 2.6 7.4 8.7 9.3 5.6 6.0 1.9 1 1 0 1 1 1 0 Life-span regulatory factor zf-C2H2 PF00096.21 KLO18005.1 - 0.00029 21.0 1.8 0.00045 20.3 1.2 1.3 1 0 0 1 1 1 1 Zinc finger, C2H2 type zf-Di19 PF05605.7 KLO18005.1 - 0.0025 17.8 0.6 0.0035 17.4 0.4 1.2 1 0 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_jaz PF12171.3 KLO18005.1 - 0.0046 17.0 0.0 0.0068 16.5 0.0 1.3 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.1 KLO18005.1 - 0.0055 16.9 1.8 0.01 16.0 1.3 1.5 1 0 0 1 1 1 1 C2H2-type zinc finger TraV PF09676.5 KLO18005.1 - 0.059 14.0 0.3 0.067 13.8 0.2 1.1 1 0 0 1 1 1 0 Type IV conjugative transfer system lipoprotein (TraV) zf-FCS PF06467.9 KLO18005.1 - 0.1 12.2 0.4 0.16 11.6 0.3 1.3 1 0 0 1 1 1 0 MYM-type Zinc finger with FCS sequence motif Iso_dh PF00180.15 KLO18006.1 - 7.9e-79 265.1 0.0 8.9e-79 264.9 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase DUF1504 PF07399.6 KLO18006.1 - 0.12 10.9 0.2 0.24 9.9 0.1 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1504) Abhydrolase_6 PF12697.2 KLO18007.1 - 3e-05 24.0 0.0 0.00012 21.9 0.0 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family MFS_1 PF07690.11 KLO18008.1 - 7.3e-40 136.7 49.8 8.2e-39 133.3 33.5 2.4 2 1 0 2 2 2 1 Major Facilitator Superfamily MFS_2 PF13347.1 KLO18008.1 - 0.0016 16.9 27.6 0.0016 16.9 19.1 3.2 1 1 2 3 3 3 2 MFS/sugar transport protein DUF3087 PF11286.3 KLO18008.1 - 0.077 12.2 2.7 0.19 10.9 0.5 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF3087) L1R_F9L PF02442.12 KLO18008.1 - 0.094 12.1 1.6 0.3 10.5 0.6 2.3 2 0 0 2 2 2 0 Lipid membrane protein of large eukaryotic DNA viruses DUF3377 PF11857.3 KLO18008.1 - 0.61 9.7 3.3 0.94 9.1 0.0 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3377) DUF4149 PF13664.1 KLO18008.1 - 2.6 8.1 24.6 0.085 12.9 0.6 4.5 3 1 1 5 5 5 0 Domain of unknown function (DUF4149) DUF680 PF05079.7 KLO18008.1 - 4.5 7.8 6.4 0.65 10.5 0.8 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF680) GST_N_3 PF13417.1 KLO18009.1 - 3.4e-09 36.8 0.0 6.3e-09 35.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 KLO18009.1 - 4.3e-06 26.6 0.0 7.6e-06 25.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 KLO18009.1 - 0.012 15.5 0.0 0.019 14.9 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 KLO18009.1 - 0.017 15.0 0.0 0.034 14.0 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 KLO18009.1 - 0.088 13.2 0.0 0.14 12.6 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Piwi PF02171.12 KLO18011.1 - 1.1e-87 293.8 0.0 1.4e-87 293.4 0.0 1.2 1 0 0 1 1 1 1 Piwi domain DUF1785 PF08699.5 KLO18011.1 - 1.4e-16 59.5 0.0 5e-16 57.8 0.0 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF1785) PAZ PF02170.17 KLO18011.1 - 5e-13 48.5 0.0 1.5e-12 46.9 0.0 1.7 2 0 0 2 2 2 1 PAZ domain Histidinol_dh PF00815.15 KLO18012.1 - 3.3e-175 582.6 2.7 4.9e-175 582.0 1.9 1.2 1 0 0 1 1 1 1 Histidinol dehydrogenase PRA-CH PF01502.13 KLO18012.1 - 1.5e-24 85.4 0.1 3.3e-24 84.3 0.1 1.6 1 0 0 1 1 1 1 Phosphoribosyl-AMP cyclohydrolase PRA-PH PF01503.12 KLO18012.1 - 2.4e-10 40.5 0.1 6.8e-10 39.0 0.1 1.8 1 0 0 1 1 1 1 Phosphoribosyl-ATP pyrophosphohydrolase Transket_pyr PF02779.19 KLO18013.1 - 2e-47 160.9 0.0 5.8e-47 159.4 0.0 1.7 2 0 0 2 2 2 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.15 KLO18013.1 - 4.3e-40 136.4 0.1 1e-39 135.2 0.1 1.6 1 0 0 1 1 1 1 Transketolase, C-terminal domain Aldolase PF01081.14 KLO18013.1 - 0.1 11.7 0.3 0.18 10.9 0.2 1.3 1 0 0 1 1 1 0 KDPG and KHG aldolase adh_short PF00106.20 KLO18014.1 - 4.4e-31 108.0 0.1 6.2e-31 107.5 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KLO18014.1 - 7.3e-18 65.2 0.0 9.1e-18 64.8 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KLO18014.1 - 1.7e-13 50.6 0.5 5.9e-13 48.8 0.3 1.7 1 1 0 1 1 1 1 KR domain Epimerase PF01370.16 KLO18014.1 - 3.7e-05 23.2 0.0 0.00012 21.6 0.0 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.3 KLO18014.1 - 0.00055 19.6 0.3 0.0016 18.2 0.1 1.8 2 0 0 2 2 2 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase NAD_binding_10 PF13460.1 KLO18014.1 - 0.00063 19.7 0.0 0.0025 17.8 0.0 1.8 1 1 0 1 1 1 1 NADH(P)-binding THF_DHG_CYH_C PF02882.14 KLO18014.1 - 0.042 12.9 0.1 0.35 9.9 0.1 2.1 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Hid1 PF12722.2 KLO18016.1 - 0.2 9.2 2.8 0.26 8.8 1.9 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein GST_N_3 PF13417.1 KLO18017.1 - 1.8e-11 44.1 0.0 3.5e-11 43.1 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 KLO18017.1 - 2.1e-08 34.0 0.0 5e-08 32.8 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 KLO18017.1 - 0.00035 20.3 0.5 0.002 18.0 0.0 2.1 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 KLO18017.1 - 0.0022 18.4 0.1 0.0037 17.7 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 KLO18017.1 - 0.0042 17.2 0.0 0.012 15.7 0.0 1.9 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 KLO18017.1 - 0.03 14.2 0.0 0.065 13.2 0.0 1.5 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 KLO18018.1 - 3.9e-12 46.2 0.0 1e-11 44.9 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 KLO18018.1 - 1.2e-09 37.9 0.0 2.6e-09 36.9 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 KLO18018.1 - 7.2e-05 22.8 0.0 0.00091 19.3 0.0 2.5 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 KLO18018.1 - 9.5e-05 22.2 0.0 0.00021 21.1 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 KLO18018.1 - 0.00015 22.2 0.0 0.00026 21.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 KLO18018.1 - 0.00065 19.6 0.0 0.001 18.9 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Raptor_N PF14538.1 KLO18019.1 - 1.1e-62 210.3 0.1 2.1e-62 209.5 0.1 1.5 1 0 0 1 1 1 1 Raptor N-terminal CASPase like domain WD40 PF00400.27 KLO18019.1 - 1.4e-12 46.9 12.2 7.8e-05 22.4 0.4 7.1 7 0 0 7 7 7 4 WD domain, G-beta repeat HEAT PF02985.17 KLO18019.1 - 8.9e-10 37.8 1.1 7.5e-05 22.4 0.0 5.4 5 0 0 5 5 5 1 HEAT repeat HEAT_2 PF13646.1 KLO18019.1 - 3.1e-05 24.1 0.1 0.01 16.0 0.0 3.3 3 1 1 4 4 4 2 HEAT repeats HEAT_EZ PF13513.1 KLO18019.1 - 0.0021 18.5 1.6 0.08 13.4 0.0 3.6 3 0 0 3 3 3 1 HEAT-like repeat Sec34 PF04136.10 KLO18020.1 - 0.0016 18.1 0.9 0.0016 18.1 0.6 4.6 3 2 0 4 4 4 2 Sec34-like family HALZ PF02183.13 KLO18020.1 - 0.021 14.5 0.9 0.021 14.5 0.6 5.7 7 0 0 7 7 7 0 Homeobox associated leucine zipper CK_II_beta PF01214.13 KLO18022.1 - 3.1e-77 258.2 0.0 4.2e-77 257.8 0.0 1.2 1 0 0 1 1 1 1 Casein kinase II regulatory subunit YL1 PF05764.8 KLO18022.1 - 0.0003 20.4 3.7 0.00041 20.0 2.6 1.1 1 0 0 1 1 1 1 YL1 nuclear protein Nop14 PF04147.7 KLO18022.1 - 0.084 10.7 14.2 0.11 10.3 9.8 1.1 1 0 0 1 1 1 0 Nop14-like family DUF2890 PF11081.3 KLO18022.1 - 0.27 11.2 9.4 0.53 10.3 6.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) Daxx PF03344.10 KLO18022.1 - 0.3 9.5 12.4 0.44 8.9 8.6 1.2 1 0 0 1 1 1 0 Daxx Family DUF2457 PF10446.4 KLO18022.1 - 0.31 9.7 12.5 0.44 9.2 8.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Paf1 PF03985.8 KLO18022.1 - 0.88 8.2 11.4 1.1 7.8 7.9 1.1 1 0 0 1 1 1 0 Paf1 CDC45 PF02724.9 KLO18022.1 - 1.3 6.9 8.7 1.6 6.6 6.0 1.1 1 0 0 1 1 1 0 CDC45-like protein SDA1 PF05285.7 KLO18022.1 - 2.1 7.5 15.9 3 7.0 11.0 1.1 1 0 0 1 1 1 0 SDA1 BUD22 PF09073.5 KLO18022.1 - 2.8 6.9 12.2 3.9 6.4 8.4 1.1 1 0 0 1 1 1 0 BUD22 Ribosomal_L36e PF01158.13 KLO18023.1 - 2.2e-39 133.4 5.1 2.4e-39 133.2 3.5 1.0 1 0 0 1 1 1 1 Ribosomal protein L36e 4HB_MCP_1 PF12729.2 KLO18023.1 - 0.021 14.2 0.0 0.024 13.9 0.0 1.1 1 0 0 1 1 1 0 Four helix bundle sensory module for signal transduction DUF3150 PF11348.3 KLO18023.1 - 0.027 13.5 0.2 0.03 13.4 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3150) Hydantoinase_A PF01968.13 KLO18024.1 - 1.1e-88 297.0 0.0 1.9e-88 296.3 0.0 1.4 1 0 0 1 1 1 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.8 KLO18024.1 - 1.1e-54 184.5 0.1 9e-52 175.1 0.0 2.6 2 0 0 2 2 2 2 Hydantoinase/oxoprolinase N-terminal region SNARE_assoc PF09335.6 KLO18026.1 - 1.4e-17 64.0 1.7 1.4e-17 64.0 1.2 2.5 3 1 0 3 3 3 1 SNARE associated Golgi protein COBRA1 PF06209.8 KLO18027.1 - 4.8 5.6 2.0 7.3 5.0 1.4 1.2 1 0 0 1 1 1 0 Cofactor of BRCA1 (COBRA1) Mito_carr PF00153.22 KLO18028.1 - 6.9e-66 218.0 3.8 1.2e-24 85.8 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein EF-hand_7 PF13499.1 KLO18028.1 - 0.00021 21.3 0.0 0.00068 19.7 0.0 1.9 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.27 KLO18028.1 - 0.0011 18.1 0.0 0.037 13.3 0.0 2.7 2 0 0 2 2 2 1 EF hand EF-hand_6 PF13405.1 KLO18028.1 - 0.0027 17.4 0.0 0.042 13.7 0.0 2.8 3 0 0 3 3 3 1 EF-hand domain EF-hand_5 PF13202.1 KLO18028.1 - 0.014 14.7 0.3 0.1 11.9 0.1 2.4 2 0 0 2 2 2 0 EF hand MFS_1 PF07690.11 KLO18029.1 - 6.6e-38 130.3 27.7 9.1e-38 129.8 19.2 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Lzipper-MIP1 PF14389.1 KLO18030.1 - 0.072 13.1 2.9 0.1 12.6 0.1 2.4 2 1 0 2 2 2 0 Leucine-zipper of ternary complex factor MIP1 Ran-binding PF05508.6 KLO18030.1 - 0.074 11.9 1.2 0.089 11.6 0.8 1.1 1 0 0 1 1 1 0 RanGTP-binding protein DUF848 PF05852.6 KLO18030.1 - 1.3 8.8 6.3 1.1 9.0 3.3 1.6 1 1 1 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) Striatin PF08232.7 KLO18030.1 - 2.4 8.4 7.4 75 3.6 5.1 2.0 1 1 0 1 1 1 0 Striatin family Ribosomal_L6e PF01159.14 KLO18031.1 - 2.3e-38 130.7 0.2 4e-38 129.9 0.2 1.4 1 0 0 1 1 1 1 Ribosomal protein L6e CRCB PF02537.10 KLO18033.1 - 2.6e-33 114.3 21.6 1e-20 73.7 5.1 2.6 2 1 0 2 2 2 2 CrcB-like protein Nitrate_red_gam PF02665.9 KLO18034.1 - 0.0081 15.5 1.6 0.016 14.5 1.1 1.5 1 1 0 1 1 1 1 Nitrate reductase gamma subunit 60KD_IMP PF02096.15 KLO18035.1 - 3.3e-18 66.0 0.1 2.5e-17 63.1 0.1 2.2 1 1 0 1 1 1 1 60Kd inner membrane protein DNA_pol_E_B PF04042.11 KLO18036.1 - 6.4e-37 126.8 0.2 1.1e-36 126.0 0.1 1.4 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B HAD_2 PF13419.1 KLO18037.1 - 2.9e-33 115.5 0.3 3.8e-33 115.1 0.2 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 KLO18037.1 - 9.8e-06 26.1 0.0 0.00045 20.6 0.0 2.3 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 KLO18037.1 - 2.5e-05 23.8 0.0 6e-05 22.6 0.0 1.6 1 0 0 1 1 1 1 HAD-hyrolase-like Acid_PPase PF12689.2 KLO18037.1 - 0.00044 19.9 0.0 0.009 15.6 0.0 2.1 2 0 0 2 2 2 1 Acid Phosphatase TOM20_plant PF06552.7 KLO18037.1 - 0.14 11.7 0.1 0.32 10.5 0.0 1.6 2 0 0 2 2 2 0 Plant specific mitochondrial import receptor subunit TOM20 MFS_1 PF07690.11 KLO18038.1 - 1.4e-50 172.0 42.4 9.5e-50 169.2 28.7 2.2 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 KLO18038.1 - 4.8e-22 77.9 13.7 5.6e-22 77.6 9.5 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 KLO18038.1 - 1.9e-11 43.2 23.4 2.1e-11 43.0 6.7 2.3 2 0 0 2 2 2 2 Sugar (and other) transporter DUF3040 PF11239.3 KLO18038.1 - 3.1 7.9 5.6 2.7 8.1 0.1 3.5 3 1 1 4 4 4 0 Protein of unknown function (DUF3040) HAD_2 PF13419.1 KLO18039.1 - 5.6e-26 91.8 0.6 4.8e-25 88.7 0.1 2.0 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 KLO18039.1 - 0.00021 21.7 0.0 0.0016 18.9 0.0 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase UPF0183 PF03676.9 KLO18040.1 - 1.7e-38 132.2 0.0 9.8e-33 113.2 0.0 3.0 2 1 0 2 2 2 2 Uncharacterised protein family (UPF0183) Apt1 PF10351.4 KLO18042.1 - 1.2e-73 248.5 1.0 2.7e-73 247.4 0.7 1.6 1 1 0 1 1 1 1 Golgi-body localisation protein domain Fmp27_WPPW PF10359.4 KLO18042.1 - 9.7e-64 215.5 0.0 1.9e-63 214.5 0.0 1.4 1 0 0 1 1 1 1 RNA pol II promoter Fmp27 protein domain Fmp27_GFWDK PF10347.4 KLO18042.1 - 4.3e-39 133.9 0.0 8.8e-39 132.9 0.0 1.6 1 0 0 1 1 1 1 RNA pol II promoter Fmp27 protein domain DUF2405 PF10293.4 KLO18042.1 - 7.2e-24 84.3 0.0 3.8e-23 81.9 0.0 2.3 1 0 0 1 1 1 1 Domain of unknown function (DUF2405) Fmp27_SW PF10305.4 KLO18042.1 - 2.5e-13 50.3 0.0 1.3e-12 48.0 0.0 2.3 3 0 0 3 3 3 1 RNA pol II promoter Fmp27 protein domain Fmp27 PF10344.4 KLO18042.1 - 3.5e-07 28.3 5.9 0.00016 19.5 2.7 2.8 2 1 0 2 2 2 2 Mitochondrial protein from FMP27 NAD_binding_10 PF13460.1 KLO18043.1 - 2.5e-10 40.6 0.3 3.8e-10 40.0 0.2 1.1 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 KLO18043.1 - 1.4e-05 24.6 0.0 1.9e-05 24.2 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Semialdhyde_dh PF01118.19 KLO18043.1 - 0.0002 21.6 0.1 0.00063 20.0 0.1 1.9 1 1 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain adh_short PF00106.20 KLO18043.1 - 0.013 15.4 6.0 0.18 11.6 0.8 3.0 2 1 0 2 2 2 0 short chain dehydrogenase NAD_binding_4 PF07993.7 KLO18043.1 - 0.031 13.1 0.3 5.3 5.8 0.1 2.2 1 1 0 2 2 2 0 Male sterility protein DapB_N PF01113.15 KLO18043.1 - 0.096 12.6 0.1 0.26 11.2 0.0 1.7 1 1 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Shikimate_DH PF01488.15 KLO18043.1 - 0.12 12.5 0.1 0.2 11.7 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase NAD_binding_10 PF13460.1 KLO18044.1 - 7.4e-08 32.6 0.1 1e-07 32.1 0.0 1.1 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 KLO18044.1 - 0.0018 17.7 0.0 0.0024 17.3 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short PF00106.20 KLO18044.1 - 0.032 14.1 1.1 2 8.3 0.7 2.2 1 1 0 1 1 1 0 short chain dehydrogenase DapB_N PF01113.15 KLO18044.1 - 0.074 12.9 0.3 0.14 12.1 0.1 1.6 1 1 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus HAD_2 PF13419.1 KLO18045.1 - 6.6e-14 52.5 0.0 1.2e-13 51.6 0.0 1.4 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 KLO18045.1 - 5.4e-10 38.8 0.0 1e-09 37.9 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.21 KLO18045.1 - 9.2e-10 39.2 0.0 7.3e-07 29.8 0.0 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 KLO18045.1 - 0.019 15.1 0.0 0.032 14.4 0.0 1.5 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase DCX PF03607.12 KLO18045.1 - 0.13 11.9 0.2 0.65 9.6 0.0 2.2 2 0 0 2 2 2 0 Doublecortin Tubulin PF00091.20 KLO18046.1 - 1.3e-68 231.0 0.0 1.7e-68 230.6 0.0 1.1 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 KLO18046.1 - 5.8e-47 158.8 0.0 8.6e-47 158.3 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.1 KLO18046.1 - 0.0003 20.2 0.0 0.00056 19.4 0.0 1.5 1 0 0 1 1 1 1 Tubulin domain Lipase_3 PF01764.20 KLO18046.1 - 0.014 15.0 0.0 3.4 7.2 0.0 2.3 2 0 0 2 2 2 0 Lipase (class 3) Abhydrolase_3 PF07859.8 KLO18047.1 - 1.7e-38 132.3 0.1 8.2e-30 103.9 0.0 2.5 2 0 0 2 2 2 2 alpha/beta hydrolase fold DUF2424 PF10340.4 KLO18047.1 - 6.8e-10 38.1 0.0 1.8e-09 36.7 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF2424) Abhydrolase_5 PF12695.2 KLO18047.1 - 0.0036 17.0 0.0 0.0077 15.9 0.0 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 KLO18047.1 - 0.025 14.0 0.0 0.073 12.4 0.0 1.7 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase DSPc PF00782.15 KLO18048.1 - 1.8e-32 111.7 0.0 2.1e-32 111.4 0.0 1.1 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 KLO18048.1 - 4.7e-05 22.8 0.0 6.2e-05 22.4 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Init_tRNA_PT PF04179.7 KLO18048.1 - 0.034 13.0 0.0 0.039 12.8 0.0 1.0 1 0 0 1 1 1 0 Initiator tRNA phosphoribosyl transferase Myotub-related PF06602.9 KLO18048.1 - 0.12 11.1 0.0 0.15 10.7 0.0 1.1 1 0 0 1 1 1 0 Myotubularin-like phosphatase domain PTPlike_phytase PF14566.1 KLO18048.1 - 0.13 12.2 0.0 0.2 11.7 0.0 1.3 1 0 0 1 1 1 0 Inositol hexakisphosphate Meth_synt_2 PF01717.13 KLO18049.1 - 1.6e-143 477.5 0.0 4.1e-139 463.0 0.0 2.3 2 0 0 2 2 2 2 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.7 KLO18049.1 - 2.4e-122 408.0 0.0 5.4e-112 374.0 0.0 3.1 3 0 0 3 3 3 3 Cobalamin-independent synthase, N-terminal domain URO-D PF01208.12 KLO18049.1 - 0.048 12.5 0.0 0.33 9.8 0.0 2.3 3 0 0 3 3 3 0 Uroporphyrinogen decarboxylase (URO-D) Rsd_AlgQ PF04353.8 KLO18049.1 - 0.072 12.7 0.1 0.95 9.1 0.0 2.4 2 0 0 2 2 2 0 Regulator of RNA polymerase sigma(70) subunit, Rsd/AlgQ DUF2985 PF11204.3 KLO18050.1 - 1.5e-29 101.5 4.5 3.4e-29 100.4 3.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2985) Sec15 PF04091.7 KLO18051.1 - 2.3e-73 247.2 3.0 2.3e-73 247.2 2.1 1.7 2 0 0 2 2 2 1 Exocyst complex subunit Sec15-like COG5 PF10392.4 KLO18051.1 - 1.1e-06 28.6 1.0 1.1e-06 28.6 0.7 3.9 3 1 0 4 4 4 1 Golgi transport complex subunit 5 Vps51 PF08700.6 KLO18051.1 - 5.7e-06 26.0 0.8 3.4e-05 23.5 0.1 2.7 1 1 1 2 2 2 1 Vps51/Vps67 Sec8_exocyst PF04048.9 KLO18051.1 - 4.7e-05 23.0 1.9 4.7e-05 23.0 1.3 3.6 4 0 0 4 4 4 1 Sec8 exocyst complex component specific domain Sec5 PF15469.1 KLO18051.1 - 0.00024 20.9 0.7 0.0013 18.5 0.5 2.3 1 0 0 1 1 1 1 Exocyst complex component Sec5 COG2 PF06148.6 KLO18051.1 - 0.0078 16.0 10.4 0.074 12.9 2.0 3.9 4 0 0 4 4 4 1 COG (conserved oligomeric Golgi) complex component, COG2 DUF2664 PF10867.3 KLO18051.1 - 0.057 14.0 1.3 0.55 10.8 0.5 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2664) NPV_P10 PF05531.7 KLO18051.1 - 0.74 10.1 5.5 1 9.6 0.8 3.7 3 0 0 3 3 3 0 Nucleopolyhedrovirus P10 protein Reo_sigmaC PF04582.7 KLO18051.1 - 0.9 8.6 8.2 0.2 10.8 0.3 2.7 2 0 0 2 2 2 0 Reovirus sigma C capsid protein Arf PF00025.16 KLO18052.1 - 5.2e-70 234.2 0.0 5.9e-70 234.0 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 KLO18052.1 - 3.4e-14 52.4 0.0 4.2e-14 52.1 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.17 KLO18052.1 - 3e-13 49.4 0.0 3.3e-13 49.3 0.0 1.1 1 0 0 1 1 1 1 Ras family G-alpha PF00503.15 KLO18052.1 - 2.9e-10 39.3 1.0 3.1e-08 32.7 0.2 2.1 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.7 KLO18052.1 - 9.2e-09 34.7 0.0 1e-08 34.5 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 KLO18052.1 - 9.3e-09 35.8 0.0 1.3e-08 35.3 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 KLO18052.1 - 1.9e-05 24.6 0.0 2.7e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 KLO18052.1 - 0.0055 16.1 0.0 0.059 12.8 0.0 1.9 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain 6PF2K PF01591.13 KLO18052.1 - 0.024 13.6 0.1 0.035 13.1 0.0 1.2 1 0 0 1 1 1 0 6-phosphofructo-2-kinase AAA_33 PF13671.1 KLO18052.1 - 0.051 13.4 0.1 0.082 12.7 0.0 1.5 1 1 0 1 1 1 0 AAA domain CPSF100_C PF13299.1 KLO18053.1 - 5.5e-30 104.6 0.0 5.5e-30 104.6 0.0 2.7 3 0 0 3 3 3 1 Cleavage and polyadenylation factor 2 C-terminal Beta-Casp PF10996.3 KLO18053.1 - 2.1e-21 76.1 0.0 5.3e-21 74.8 0.0 1.7 1 0 0 1 1 1 1 Beta-Casp domain Lactamase_B_2 PF12706.2 KLO18053.1 - 2.2e-06 27.3 0.1 8.2e-06 25.4 0.0 1.9 2 0 0 2 2 2 1 Beta-lactamase superfamily domain Arf PF00025.16 KLO18054.1 - 4.4e-78 260.5 0.2 5.1e-78 260.2 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 KLO18054.1 - 3.4e-13 49.2 0.0 4.2e-13 48.9 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.17 KLO18054.1 - 1.4e-12 47.3 0.0 1.5e-12 47.2 0.0 1.1 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.7 KLO18054.1 - 1.2e-11 44.2 0.0 1.4e-11 44.0 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region G-alpha PF00503.15 KLO18054.1 - 2.4e-11 42.9 1.6 4.3e-08 32.2 0.1 2.4 1 1 1 2 2 2 2 G-protein alpha subunit Miro PF08477.8 KLO18054.1 - 3e-08 34.1 0.0 4.3e-08 33.6 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 KLO18054.1 - 6.2e-06 26.1 0.0 8.6e-06 25.7 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.13 KLO18054.1 - 0.0074 15.3 0.1 0.023 13.7 0.0 1.7 2 0 0 2 2 2 1 6-phosphofructo-2-kinase GTP_EFTU PF00009.22 KLO18054.1 - 0.012 15.0 0.1 0.11 11.9 0.0 1.9 1 1 1 2 2 2 0 Elongation factor Tu GTP binding domain AAA_33 PF13671.1 KLO18054.1 - 0.069 13.0 0.1 0.12 12.2 0.1 1.7 1 1 0 1 1 1 0 AAA domain PduV-EutP PF10662.4 KLO18054.1 - 0.12 11.8 0.0 1.8 8.0 0.0 2.1 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation tRNA-synt_1c PF00749.16 KLO18055.1 - 2.9e-93 311.9 0.0 9.2e-93 310.3 0.0 1.8 1 1 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA_synt_1c_R1 PF04558.10 KLO18055.1 - 2e-33 115.2 0.1 3.4e-33 114.4 0.0 1.3 1 0 0 1 1 1 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1 tRNA-synt_1c_C PF03950.13 KLO18055.1 - 6.9e-28 97.4 0.0 1.5e-27 96.4 0.0 1.5 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain tRNA_synt_1c_R2 PF04557.10 KLO18055.1 - 3.4e-09 37.2 3.5 7.3e-09 36.2 0.1 2.6 2 0 0 2 2 2 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 2 AAA PF00004.24 KLO18057.1 - 3.3e-20 72.6 0.0 5.6e-20 71.8 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 KLO18057.1 - 0.0084 16.2 0.3 0.19 11.8 0.0 2.3 1 1 0 2 2 2 1 AAA domain AAA_10 PF12846.2 KLO18057.1 - 0.089 12.2 0.1 0.13 11.6 0.0 1.5 1 1 0 1 1 1 0 AAA-like domain AAA_16 PF13191.1 KLO18057.1 - 0.13 12.2 0.1 1.1 9.1 0.0 2.2 1 1 1 2 2 2 0 AAA ATPase domain MAS20 PF02064.10 KLO18058.1 - 5.4e-14 52.1 3.0 7.5e-13 48.4 2.1 2.5 1 1 0 1 1 1 1 MAS20 protein import receptor SET PF00856.23 KLO18058.1 - 1.3e-10 41.8 0.0 7.6e-08 32.8 0.0 2.8 2 1 1 3 3 3 2 SET domain zf-MYND PF01753.13 KLO18058.1 - 0.00041 20.1 0.6 0.00041 20.1 0.4 1.7 2 0 0 2 2 2 1 MYND finger COX14 PF14880.1 KLO18058.1 - 0.0029 17.2 0.0 0.0073 15.9 0.0 1.8 1 0 0 1 1 1 1 Cytochrome oxidase c assembly Ecl1 PF12855.2 KLO18058.1 - 0.013 14.8 0.5 0.028 13.7 0.3 1.6 1 0 0 1 1 1 0 Life-span regulatory factor DAGK_cat PF00781.19 KLO18058.1 - 0.089 12.2 0.0 0.2 11.0 0.0 1.5 1 0 0 1 1 1 0 Diacylglycerol kinase catalytic domain DUF2685 PF10886.3 KLO18058.1 - 0.17 11.8 4.5 0.75 9.8 1.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2685) GST_N_3 PF13417.1 KLO18059.1 - 1.3e-09 38.1 0.0 2.6e-09 37.1 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 KLO18059.1 - 6e-06 26.1 0.0 9.3e-06 25.5 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 KLO18059.1 - 0.0082 16.0 0.0 0.015 15.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 KLO18059.1 - 0.036 14.0 0.0 0.096 12.6 0.0 1.8 2 0 0 2 2 2 0 Glutathione S-transferase, N-terminal domain DUF1237 PF06824.6 KLO18061.1 - 5.9e-149 496.2 0.0 6.9e-149 496.0 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1237) Exo_endo_phos PF03372.18 KLO18062.1 - 1.2e-16 61.3 0.1 1.4e-16 61.1 0.1 1.0 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Cut8_N PF14482.1 KLO18062.1 - 0.042 13.8 0.0 0.083 12.8 0.0 1.4 1 0 0 1 1 1 0 Cut8 proteasome-binding domain WD40 PF00400.27 KLO18063.1 - 3.1e-15 55.3 13.0 1.9e-06 27.4 0.8 6.5 6 0 0 6 6 6 5 WD domain, G-beta repeat Acetyltransf_7 PF13508.1 KLO18064.1 - 2.4e-08 33.9 0.0 3.2e-08 33.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 KLO18064.1 - 7.4e-07 29.3 0.0 1.1e-06 28.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 KLO18064.1 - 1.3e-06 28.3 0.0 1.9e-06 27.7 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_9 PF13527.1 KLO18064.1 - 5.7e-06 26.2 0.0 8.4e-06 25.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 KLO18064.1 - 6.2e-05 22.6 0.0 0.0002 21.0 0.0 1.8 2 0 0 2 2 2 1 FR47-like protein SIP1 PF04938.7 KLO18065.1 - 4.4e-19 68.7 0.4 1.8e-09 37.3 0.0 2.1 2 0 0 2 2 2 2 Survival motor neuron (SMN) interacting protein 1 (SIP1) DUF3245 PF11595.3 KLO18066.1 - 4.4e-09 36.7 10.0 4.4e-09 36.7 6.9 3.0 3 1 0 3 3 3 1 Protein of unknown function (DUF3245) DUF2702 PF10863.3 KLO18066.1 - 0.0086 15.7 0.8 0.0086 15.7 0.6 3.0 3 0 0 3 3 3 1 Protein of unknown function (DUF2702) NST1 PF13945.1 KLO18066.1 - 4.7 7.2 19.0 1 9.3 0.3 3.4 3 0 0 3 3 3 0 Salt tolerance down-regulator EAP30 PF04157.11 KLO18068.1 - 1.4e-49 168.2 0.0 1.6e-49 168.0 0.0 1.0 1 0 0 1 1 1 1 EAP30/Vps36 family Pkinase PF00069.20 KLO18071.1 - 8.1e-71 238.2 0.0 1.2e-70 237.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KLO18071.1 - 6.8e-32 110.5 0.0 2.8e-30 105.2 0.0 2.3 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KLO18071.1 - 6.3e-05 22.0 1.8 0.64 8.9 0.2 3.6 3 1 0 3 3 3 2 Kinase-like RIO1 PF01163.17 KLO18071.1 - 0.00043 19.6 0.3 0.00043 19.6 0.2 1.6 2 0 0 2 2 2 1 RIO1 family DUF1764 PF08576.5 KLO18071.1 - 3.1 8.6 5.8 4 8.2 0.2 2.6 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF1764) Mg_trans_NIPA PF05653.9 KLO18072.1 - 1.8e-60 204.4 10.7 5.2e-56 189.8 4.6 2.0 2 0 0 2 2 2 2 Magnesium transporter NIPA EmrE PF13536.1 KLO18072.1 - 6.4e-06 26.3 0.1 6.4e-06 26.3 0.1 3.7 3 1 1 4 4 4 1 Multidrug resistance efflux transporter EamA PF00892.15 KLO18072.1 - 0.00012 22.0 0.8 0.00012 22.0 0.5 3.8 3 1 1 4 4 4 1 EamA-like transporter family IncA PF04156.9 KLO18072.1 - 0.07 12.7 1.0 0.26 10.8 0.0 2.2 2 0 0 2 2 2 0 IncA protein WD40 PF00400.27 KLO18073.1 - 1.8e-18 65.6 0.3 1.6e-07 30.9 0.0 3.4 4 0 0 4 4 4 2 WD domain, G-beta repeat Kelch_6 PF13964.1 KLO18073.1 - 0.038 14.1 1.1 1.8 8.8 0.0 3.5 4 0 0 4 4 4 0 Kelch motif TFIID-31kDa PF02291.10 KLO18074.1 - 1.4e-26 92.7 0.0 1.5e-26 92.6 0.0 1.0 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.8 KLO18074.1 - 9.3e-05 22.0 0.0 0.00015 21.4 0.0 1.3 1 0 0 1 1 1 1 Bromodomain associated CENP-S PF15630.1 KLO18074.1 - 0.00018 21.6 0.0 0.00024 21.2 0.0 1.1 1 0 0 1 1 1 1 Kinetochore component CENP-S Histone PF00125.19 KLO18074.1 - 0.0037 17.3 0.0 0.0051 16.8 0.0 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 FMN_red PF03358.10 KLO18074.1 - 0.1 12.0 0.0 0.13 11.7 0.0 1.1 1 0 0 1 1 1 0 NADPH-dependent FMN reductase DUF2415 PF10313.4 KLO18074.1 - 0.12 12.0 0.0 0.19 11.4 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein domain (DUF2415) Actin PF00022.14 KLO18076.1 - 6.6e-25 87.3 0.0 3.4e-10 38.9 0.0 3.6 4 0 0 4 4 4 3 Actin MreB_Mbl PF06723.8 KLO18076.1 - 0.00039 19.1 0.0 0.0023 16.5 0.0 1.9 2 0 0 2 2 2 1 MreB/Mbl protein LSM PF01423.17 KLO18077.1 - 1.9e-18 65.7 0.0 2.2e-18 65.5 0.0 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 KLO18077.1 - 0.13 12.1 0.0 0.17 11.8 0.0 1.2 1 0 0 1 1 1 0 Ataxin 2 SM domain DUF3722 PF12519.3 KLO18079.1 - 3.6e-79 265.6 0.0 4.8e-79 265.2 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3722) Pkr1 PF08636.5 KLO18080.1 - 1.1e-12 47.8 7.4 1.4e-12 47.4 5.1 1.1 1 0 0 1 1 1 1 ER protein Pkr1 FUSC PF04632.7 KLO18080.1 - 0.015 13.7 2.0 0.02 13.3 1.4 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family Spore_YabQ PF09578.5 KLO18080.1 - 0.037 13.9 2.4 0.046 13.6 1.7 1.2 1 0 0 1 1 1 0 Spore cortex protein YabQ (Spore_YabQ) DUF2244 PF10003.4 KLO18080.1 - 0.053 12.8 0.3 0.062 12.6 0.2 1.2 1 0 0 1 1 1 0 Integral membrane protein (DUF2244) Gemini_mov PF01708.11 KLO18080.1 - 0.16 11.5 2.5 0.11 12.0 0.8 1.5 1 1 1 2 2 2 0 Geminivirus putative movement protein Sld5 PF05916.6 KLO18081.1 - 2.3e-06 27.8 0.0 3.4e-06 27.2 0.0 1.3 1 0 0 1 1 1 1 GINS complex protein Tau95 PF09734.4 KLO18083.1 - 4.5e-66 223.2 0.0 6.3e-66 222.8 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase III transcription factor (TF)IIIC subunit Ribosomal_L29e PF01779.12 KLO18084.1 - 4.1e-21 74.5 13.0 5.9e-21 74.0 9.0 1.2 1 0 0 1 1 1 1 Ribosomal L29e protein family BBP1_N PF15271.1 KLO18084.1 - 0.071 13.4 0.5 0.077 13.3 0.3 1.1 1 0 0 1 1 1 0 Spindle pole body component BBP1, Mps2-binding protein Aconitase PF00330.15 KLO18085.1 - 1.6e-182 607.1 0.0 2e-182 606.8 0.0 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 KLO18085.1 - 6.6e-40 136.2 0.0 1.1e-39 135.4 0.0 1.3 1 0 0 1 1 1 1 Aconitase C-terminal domain CaM_binding PF07839.6 KLO18086.1 - 0.07 13.3 7.0 0.91 9.7 0.0 2.7 2 1 0 2 2 2 0 Plant calmodulin-binding domain DUF1675 PF07897.6 KLO18086.1 - 1.5 8.6 8.1 2.2 8.0 5.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) GTP_EFTU PF00009.22 KLO18087.1 - 1.6e-50 171.1 0.0 2.6e-50 170.4 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_C PF00679.19 KLO18087.1 - 1.3e-13 50.6 0.0 4.9e-08 32.7 0.0 2.4 2 0 0 2 2 2 2 Elongation factor G C-terminus EFG_II PF14492.1 KLO18087.1 - 3.8e-12 45.8 0.0 8.1e-12 44.8 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II GTP_EFTU_D2 PF03144.20 KLO18087.1 - 8.2e-07 29.0 0.0 1.7e-06 28.0 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 KLO18087.1 - 0.0014 18.5 0.0 0.0033 17.3 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.5 KLO18087.1 - 0.13 11.4 0.0 0.32 10.1 0.0 1.6 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit ICMT PF04140.9 KLO18088.1 - 9.5e-27 93.0 1.1 1.9e-26 92.0 0.8 1.5 1 0 0 1 1 1 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.8 KLO18088.1 - 2e-13 50.3 1.1 2e-13 50.3 0.8 1.6 2 0 0 2 2 2 1 Phospholipid methyltransferase Suc_Fer-like PF06999.7 KLO18089.1 - 1.3e-24 87.4 0.0 1.9e-24 86.9 0.0 1.2 1 0 0 1 1 1 1 Sucrase/ferredoxin-like OMPdecase PF00215.19 KLO18091.1 - 1.8e-71 240.1 0.0 2.3e-71 239.8 0.0 1.1 1 0 0 1 1 1 1 Orotidine 5'-phosphate decarboxylase / HUMPS family TruD PF01142.13 KLO18092.1 - 7.8e-68 228.8 0.0 8.7e-67 225.3 0.0 2.3 2 1 0 2 2 2 1 tRNA pseudouridine synthase D (TruD) MFS_1 PF07690.11 KLO18093.1 - 1.8e-31 109.1 22.1 1.5e-29 102.8 11.6 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily Gly_transf_sug PF04488.10 KLO18094.1 - 9.6e-21 74.1 0.2 1.7e-20 73.2 0.1 1.4 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif TcdA_TcdB PF12919.2 KLO18094.1 - 0.00038 19.0 2.0 0.1 11.0 0.1 2.1 2 0 0 2 2 2 2 TcdA/TcdB catalytic glycosyltransferase domain Caps_synth PF05704.7 KLO18094.1 - 0.11 11.6 0.1 0.16 11.0 0.0 1.2 1 0 0 1 1 1 0 Capsular polysaccharide synthesis protein PIN_4 PF13638.1 KLO18095.1 - 1e-23 83.8 0.0 2.2e-23 82.8 0.0 1.6 1 0 0 1 1 1 1 PIN domain GST_N_3 PF13417.1 KLO18097.1 - 7.6e-13 48.4 0.0 1.4e-12 47.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 KLO18097.1 - 1.2e-09 37.9 0.0 2.4e-09 37.0 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 KLO18097.1 - 1.8e-05 24.5 0.0 6.4e-05 22.7 0.0 1.8 1 1 1 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 KLO18097.1 - 2.4e-05 24.4 0.0 5.8e-05 23.1 0.0 1.7 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Tom37 PF10568.4 KLO18097.1 - 0.013 15.7 0.0 0.032 14.4 0.0 1.6 1 0 0 1 1 1 0 Outer mitochondrial membrane transport complex protein GST_C PF00043.20 KLO18097.1 - 0.015 15.3 0.0 0.026 14.4 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain MBD PF01429.14 KLO18097.1 - 0.07 12.6 0.0 0.41 10.2 0.0 1.9 2 0 0 2 2 2 0 Methyl-CpG binding domain GST_C_3 PF14497.1 KLO18097.1 - 0.11 12.9 0.0 0.2 12.1 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain MFS_1 PF07690.11 KLO18099.1 - 2.9e-43 147.9 32.7 2.2e-40 138.4 18.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF962 PF06127.6 KLO18099.1 - 0.81 9.6 7.0 0.96 9.3 2.0 3.0 2 1 0 2 2 2 0 Protein of unknown function (DUF962) RRM_1 PF00076.17 KLO18100.1 - 9.3e-19 66.8 0.4 2.6e-08 33.3 0.0 2.6 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KLO18100.1 - 1.3e-13 50.5 0.0 2e-11 43.5 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KLO18100.1 - 3.3e-11 42.9 0.1 1.3e-05 25.0 0.0 2.6 2 1 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) PBP1_TM PF14812.1 KLO18100.1 - 0.23 11.7 4.4 0.59 10.4 3.1 1.7 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal TRAM_LAG1_CLN8 PF03798.11 KLO18101.1 - 2.4e-44 151.2 21.7 4.2e-44 150.4 15.0 1.4 1 0 0 1 1 1 1 TLC domain TRAM1 PF08390.6 KLO18101.1 - 6.1e-06 25.6 0.1 1.6e-05 24.3 0.1 1.7 1 0 0 1 1 1 1 TRAM1-like protein DSPc PF00782.15 KLO18102.1 - 3.4e-36 123.7 1.0 7e-21 74.2 0.4 3.4 3 0 0 3 3 3 3 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 KLO18102.1 - 1.7e-07 30.8 0.5 0.00011 21.6 0.2 2.2 2 0 0 2 2 2 2 Protein-tyrosine phosphatase DSPn PF14671.1 KLO18102.1 - 2.7e-05 24.1 1.1 0.05 13.5 0.0 2.3 2 0 0 2 2 2 2 Dual specificity protein phosphatase, N-terminal half CDKN3 PF05706.7 KLO18102.1 - 0.025 14.0 0.6 0.33 10.3 0.0 2.2 2 0 0 2 2 2 0 Cyclin-dependent kinase inhibitor 3 (CDKN3) HCMV_UL139 PF12507.3 KLO18103.1 - 0.025 14.7 1.4 0.025 14.7 1.0 3.4 3 1 1 4 4 4 0 Human Cytomegalovirus UL139 protein HsbA PF12296.3 KLO18103.1 - 0.045 13.6 4.7 0.098 12.5 1.0 2.8 2 0 0 2 2 2 0 Hydrophobic surface binding protein A AKNA PF12443.3 KLO18103.1 - 3.2 7.8 13.1 1.4 8.9 4.0 3.6 2 1 1 3 3 3 0 AT-hook-containing transcription factor RFX_DNA_binding PF02257.10 KLO18104.1 - 1.6e-25 89.0 0.0 3.3e-25 88.0 0.0 1.5 1 0 0 1 1 1 1 RFX DNA-binding domain Metallophos PF00149.23 KLO18105.1 - 2.7e-12 46.5 1.6 4.4e-12 45.8 1.1 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase DUF4381 PF14316.1 KLO18106.1 - 0.12 12.4 0.0 0.14 12.2 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) Retrotrans_gag PF03732.12 KLO18112.1 - 0.028 14.5 0.0 0.07 13.1 0.0 1.7 1 1 0 1 1 1 0 Retrotransposon gag protein zf-C4 PF00105.13 KLO18113.1 - 3.1 8.0 7.1 0.54 10.5 1.2 2.1 2 0 0 2 2 2 0 Zinc finger, C4 type (two domains) CENP-F_C_Rb_bdg PF10490.4 KLO18114.1 - 0.12 11.7 0.0 0.19 11.0 0.0 1.2 1 0 0 1 1 1 0 Rb-binding domain of kinetochore protein Cenp-F/LEK1 CotH PF08757.6 KLO18118.1 - 0.005 16.1 0.5 0.005 16.1 0.3 1.3 2 0 0 2 2 2 1 CotH protein CAF-1_p150 PF11600.3 KLO18118.1 - 0.051 12.9 10.6 0.086 12.2 7.3 1.4 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Gluconate_2-dh3 PF13618.1 KLO18118.1 - 2.2 8.4 6.5 3.2 7.8 4.3 1.4 1 1 0 1 1 1 0 Gluconate 2-dehydrogenase subunit 3 DUF4110 PF13422.1 KLO18118.1 - 3.1 7.6 14.0 6.4 6.6 9.7 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4110) DDE_1 PF03184.14 KLO18119.1 - 5e-32 110.7 0.0 6e-32 110.5 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_3 PF13358.1 KLO18119.1 - 8.9e-06 25.5 0.0 8e-05 22.4 0.0 2.1 1 1 1 2 2 2 1 DDE superfamily endonuclease DUF3656 PF12392.3 KLO18119.1 - 0.049 13.6 0.0 0.097 12.7 0.0 1.4 1 0 0 1 1 1 0 Collagenase F-box-like PF12937.2 KLO18122.1 - 0.0061 16.2 0.0 0.017 14.8 0.0 1.7 1 0 0 1 1 1 1 F-box-like Glutaredoxin2_C PF04399.8 KLO18126.1 - 0.032 13.8 0.5 0.069 12.7 0.3 1.6 1 0 0 1 1 1 0 Glutaredoxin 2, C terminal domain NYD-SP28 PF14772.1 KLO18126.1 - 0.11 12.5 1.7 0.28 11.3 1.2 1.6 1 0 0 1 1 1 0 Sperm tail F-box-like PF12937.2 KLO18127.1 - 0.039 13.6 0.2 0.22 11.2 0.0 2.3 2 0 0 2 2 2 0 F-box-like F-box-like PF12937.2 KLO18128.1 - 0.0066 16.1 0.0 0.022 14.4 0.0 1.9 1 0 0 1 1 1 1 F-box-like MULE PF10551.4 KLO18130.1 - 0.29 11.3 1.6 1.6 8.9 0.3 2.7 3 0 0 3 3 3 0 MULE transposase domain F-box-like PF12937.2 KLO18131.1 - 0.00016 21.3 0.1 0.00016 21.3 0.1 2.4 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 KLO18131.1 - 5 6.8 6.6 18 5.1 1.3 3.6 3 1 0 3 3 3 0 F-box domain F-box-like PF12937.2 KLO18132.1 - 1.1e-07 31.4 4.0 4.8e-06 26.1 0.5 2.7 2 0 0 2 2 2 2 F-box-like LRR_4 PF12799.2 KLO18132.1 - 0.16 11.6 1.6 3.3 7.4 0.1 3.3 3 0 0 3 3 3 0 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KLO18132.1 - 0.24 11.1 5.3 20 5.0 0.1 4.1 4 0 0 4 4 4 0 Leucine rich repeat F-box-like PF12937.2 KLO18133.1 - 9.3e-07 28.4 1.0 9.3e-07 28.4 0.7 2.2 2 0 0 2 2 2 1 F-box-like zf-MYND PF01753.13 KLO18134.1 - 1.9e-08 34.0 10.1 1.9e-08 34.0 7.0 1.9 2 0 0 2 2 2 1 MYND finger Chrome_Resist PF09828.4 KLO18134.1 - 0.11 12.6 0.0 0.23 11.6 0.0 1.5 1 0 0 1 1 1 0 Chromate resistance exported protein F-box-like PF12937.2 KLO18136.1 - 8.5e-05 22.2 1.3 8.5e-05 22.2 0.9 2.5 2 1 0 2 2 2 1 F-box-like F-box PF00646.28 KLO18136.1 - 0.04 13.5 1.2 0.68 9.6 0.9 3.1 1 1 0 1 1 1 0 F-box domain DUF3557 PF12078.3 KLO18136.1 - 0.12 12.1 0.1 0.28 10.8 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3557) F-box-like PF12937.2 KLO18137.1 - 7.5e-09 35.1 3.3 9.2e-09 34.9 1.2 2.1 2 0 0 2 2 2 1 F-box-like Pkinase PF00069.20 KLO18140.1 - 2.9e-45 154.4 0.0 8.6e-44 149.6 0.0 2.1 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 KLO18140.1 - 1.9e-22 79.5 0.0 1.8e-21 76.3 0.0 2.1 2 0 0 2 2 2 1 Protein tyrosine kinase Kdo PF06293.9 KLO18140.1 - 0.00014 20.9 0.0 0.00031 19.8 0.0 1.4 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 KLO18140.1 - 0.052 12.5 0.0 0.33 9.8 0.0 1.9 2 0 0 2 2 2 0 Kinase-like Prenyltrans PF00432.16 KLO18141.1 - 7.6e-33 111.7 12.5 1.3e-07 31.0 0.2 6.1 5 1 0 5 5 5 5 Prenyltransferase and squalene oxidase repeat Prenyltrans_2 PF13249.1 KLO18141.1 - 5e-23 81.6 0.0 3.1e-18 66.2 0.0 3.4 3 1 0 3 3 3 2 Prenyltransferase-like Prenyltrans_1 PF13243.1 KLO18141.1 - 0.00012 22.0 0.0 0.013 15.5 0.0 3.2 2 1 1 3 3 3 2 Prenyltransferase-like DUF4404 PF14357.1 KLO18141.1 - 0.033 14.5 0.0 0.07 13.5 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4404) Nup84_Nup100 PF04121.8 KLO18142.1 - 3.1e-89 299.5 0.8 2.7e-88 296.4 0.6 2.1 1 1 0 1 1 1 1 Nuclear pore protein 84 / 107 BRK PF07533.11 KLO18142.1 - 0.019 14.4 0.0 0.056 12.9 0.0 1.8 1 0 0 1 1 1 0 BRK domain Pkinase PF00069.20 KLO18143.1 - 2.8e-31 108.6 0.0 3.9e-31 108.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KLO18143.1 - 6.6e-15 54.8 0.0 1e-14 54.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 KLO18143.1 - 0.0024 17.6 0.3 0.0048 16.6 0.2 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.1 KLO18143.1 - 0.11 11.4 0.0 0.19 10.6 0.0 1.3 1 0 0 1 1 1 0 Kinase-like P3A PF08727.6 KLO18143.1 - 0.17 11.2 1.1 18 4.7 0.1 2.5 2 0 0 2 2 2 0 Poliovirus 3A protein like DUF3557 PF12078.3 KLO18145.1 - 0.07 12.8 0.1 0.14 11.8 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3557) F-box-like PF12937.2 KLO18147.1 - 0.0016 18.1 0.0 0.0064 16.1 0.0 2.1 1 0 0 1 1 1 1 F-box-like zf-MYND PF01753.13 KLO18148.1 - 3.8e-09 36.2 14.4 6.4e-09 35.5 10.0 1.4 1 0 0 1 1 1 1 MYND finger zf-Mss51 PF13824.1 KLO18148.1 - 0.25 11.2 6.4 0.51 10.2 4.5 1.5 1 0 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 zinc-ribbons_6 PF07191.7 KLO18149.1 - 0.0049 16.6 0.8 0.029 14.1 0.5 2.1 3 0 0 3 3 3 1 zinc-ribbons DZR PF12773.2 KLO18149.1 - 0.05 13.4 0.8 0.077 12.8 0.6 1.3 1 0 0 1 1 1 0 Double zinc ribbon zf-P11 PF03854.9 KLO18149.1 - 0.11 11.9 0.5 0.11 11.9 0.4 2.1 2 0 0 2 2 2 0 P-11 zinc finger Phage_int_SAM_2 PF12834.2 KLO18150.1 - 0.044 14.1 0.0 0.075 13.4 0.0 1.3 1 0 0 1 1 1 0 Phage integrase, N-terminal CHAD PF05235.9 KLO18151.1 - 0.013 15.0 0.1 0.018 14.6 0.1 1.2 1 0 0 1 1 1 0 CHAD domain MutS_III PF05192.13 KLO18151.1 - 0.027 14.2 0.1 0.04 13.7 0.1 1.3 1 0 0 1 1 1 0 MutS domain III MerR-DNA-bind PF09278.6 KLO18151.1 - 0.061 13.7 1.5 1.6 9.2 0.3 2.5 2 0 0 2 2 2 0 MerR, DNA binding RdRP_3 PF00998.18 KLO18151.1 - 0.062 11.7 0.0 0.08 11.4 0.0 1.2 1 0 0 1 1 1 0 Viral RNA dependent RNA polymerase DELLA PF12041.3 KLO18151.1 - 0.12 12.0 0.3 0.41 10.3 0.1 1.9 1 1 1 2 2 2 0 Transcriptional regulator DELLA protein N terminal zf-RanBP PF00641.13 KLO18151.1 - 0.19 10.8 0.9 0.53 9.4 0.1 1.9 2 0 0 2 2 2 0 Zn-finger in Ran binding protein and others Baculo_PEP_C PF04513.7 KLO18151.1 - 0.2 11.4 4.1 0.54 10.0 2.6 1.7 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Syntaxin PF00804.20 KLO18151.1 - 0.31 11.2 4.4 5.2 7.2 3.3 2.2 1 1 0 1 1 1 0 Syntaxin Snapin_Pallidin PF14712.1 KLO18151.1 - 0.39 11.0 2.4 7.5 6.9 0.0 2.3 2 0 0 2 2 2 0 Snapin/Pallidin ZapA PF05164.8 KLO18151.1 - 0.54 10.2 2.8 3 7.8 1.0 2.3 1 1 1 2 2 2 0 Cell division protein ZapA HR1 PF02185.11 KLO18151.1 - 0.87 9.3 5.0 5.9 6.7 0.1 3.1 2 1 1 3 3 3 0 Hr1 repeat DASH_Dad3 PF08656.5 KLO18151.1 - 2.6 7.8 7.7 2.7 7.7 0.5 3.2 1 1 2 3 3 3 0 DASH complex subunit Dad3 F-box-like PF12937.2 KLO18152.1 - 4.4e-07 29.5 0.2 8.9e-07 28.5 0.1 1.5 1 0 0 1 1 1 1 F-box-like F-box-like PF12937.2 KLO18153.1 - 3.5e-05 23.4 0.4 3.5e-05 23.4 0.3 2.9 3 0 0 3 3 3 1 F-box-like F-box PF00646.28 KLO18153.1 - 0.014 15.0 8.2 10 5.9 0.0 5.3 4 2 1 5 5 5 0 F-box domain zf-MYND PF01753.13 KLO18154.1 - 1.4e-08 34.4 13.8 3.1e-08 33.3 9.5 1.6 1 0 0 1 1 1 1 MYND finger zf-Mss51 PF13824.1 KLO18154.1 - 0.51 10.2 7.5 1.3 8.9 5.2 1.7 1 0 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 LRR_8 PF13855.1 KLO18155.1 - 0.0015 18.2 0.9 3.3 7.5 0.0 3.5 3 0 0 3 3 3 2 Leucine rich repeat F-box-like PF12937.2 KLO18155.1 - 0.0059 16.3 1.6 0.015 15.0 0.2 2.5 2 0 0 2 2 2 1 F-box-like LRR_4 PF12799.2 KLO18155.1 - 0.38 10.4 7.3 4 7.1 2.3 3.9 2 1 0 2 2 2 0 Leucine Rich repeats (2 copies) Rod-binding PF10135.4 KLO18156.1 - 0.16 11.9 0.2 0.26 11.2 0.2 1.3 1 0 0 1 1 1 0 Rod binding protein SNase PF00565.12 KLO18158.1 - 9e-17 61.2 0.0 1.3e-16 60.8 0.0 1.2 1 0 0 1 1 1 1 Staphylococcal nuclease homologue PHD PF00628.24 KLO18160.1 - 0.00066 19.3 12.1 0.0014 18.2 8.4 1.5 1 0 0 1 1 1 1 PHD-finger DUF1077 PF06417.7 KLO18161.1 - 1.6e-45 153.4 0.2 2e-45 153.2 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1077) F-box-like PF12937.2 KLO18162.1 - 6.2e-05 22.6 2.2 0.0001 21.9 0.2 2.5 3 0 0 3 3 3 1 F-box-like F-box-like PF12937.2 KLO18163.1 - 1.6e-07 30.9 0.5 4.7e-07 29.4 0.3 1.9 1 0 0 1 1 1 1 F-box-like CBM_21 PF03370.8 KLO18168.1 - 2.4e-27 95.1 0.1 3.4e-26 91.4 0.0 2.2 1 1 0 1 1 1 1 Putative phosphatase regulatory subunit CBM_25 PF03423.8 KLO18168.1 - 0.025 14.6 0.2 0.37 10.8 0.0 2.3 2 0 0 2 2 2 0 Carbohydrate binding domain (family 25) zf-MYND PF01753.13 KLO18170.1 - 1.2e-09 37.8 10.8 2.7e-09 36.7 7.5 1.6 1 0 0 1 1 1 1 MYND finger zf-MYND PF01753.13 KLO18171.1 - 6.3e-10 38.7 11.5 1.6e-09 37.4 8.0 1.7 1 0 0 1 1 1 1 MYND finger zf-ribbon_3 PF13248.1 KLO18171.1 - 0.029 13.5 1.4 0.065 12.4 1.0 1.6 1 0 0 1 1 1 0 zinc-ribbon domain zf-Mss51 PF13824.1 KLO18171.1 - 0.13 12.1 2.5 0.33 10.8 1.8 1.7 1 0 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 zf-MYND PF01753.13 KLO18172.1 - 2.6e-06 27.1 19.7 5.6e-06 26.1 13.7 1.6 1 0 0 1 1 1 1 MYND finger zf-MYND PF01753.13 KLO18173.1 - 7.7e-11 41.6 11.7 1.6e-10 40.6 8.1 1.6 1 0 0 1 1 1 1 MYND finger Fer4_2 PF12797.2 KLO18173.1 - 3.4 7.7 5.3 1.4 9.0 0.9 2.5 2 0 0 2 2 2 0 4Fe-4S binding domain zf-Mss51 PF13824.1 KLO18173.1 - 5.9 6.8 9.0 0.94 9.3 3.0 2.1 3 0 0 3 3 3 0 Zinc-finger of mitochondrial splicing suppressor 51 zf-MYND PF01753.13 KLO18174.1 - 1.5e-07 31.1 11.2 1.5e-07 31.1 7.8 2.8 3 0 0 3 3 3 2 MYND finger TMEM125 PF15109.1 KLO18174.1 - 0.0061 16.6 0.0 0.022 14.8 0.0 1.9 1 0 0 1 1 1 1 TMEM125 protein family zf-MYND PF01753.13 KLO18175.1 - 8.2e-09 35.1 14.8 2e-08 33.9 10.2 1.7 1 0 0 1 1 1 1 MYND finger UQ_con PF00179.21 KLO18176.1 - 2.1e-08 33.6 0.0 4.4e-08 32.6 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Pkinase PF00069.20 KLO18177.1 - 6e-42 143.5 0.0 1.1e-41 142.7 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KLO18177.1 - 1.7e-36 125.6 0.0 2.6e-36 125.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KLO18177.1 - 1.3e-05 24.2 0.0 2.3e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 KLO18177.1 - 0.013 14.5 0.0 0.025 13.6 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 KLO18177.1 - 0.019 14.2 0.1 0.32 10.3 0.0 2.4 3 0 0 3 3 3 0 RIO1 family SAS4 PF15460.1 KLO18177.1 - 0.066 13.0 0.0 0.15 11.9 0.0 1.6 1 0 0 1 1 1 0 Something about silencing, SAS, complex subunit 4 APH PF01636.18 KLO18177.1 - 0.089 12.5 0.0 0.26 10.9 0.0 1.7 2 0 0 2 2 2 0 Phosphotransferase enzyme family zf-MYND PF01753.13 KLO18178.1 - 1.7e-08 34.1 16.1 1.7e-08 34.1 11.1 2.0 2 0 0 2 2 2 1 MYND finger zf-MYND PF01753.13 KLO18179.1 - 4.9e-10 39.1 9.8 4.9e-10 39.1 6.8 1.9 2 0 0 2 2 2 1 MYND finger Ecl1 PF12855.2 KLO18179.1 - 0.22 10.8 6.6 2 7.7 3.8 2.7 2 0 0 2 2 2 0 Life-span regulatory factor zf-Mss51 PF13824.1 KLO18179.1 - 1.3 8.8 4.1 2.9 7.8 2.8 1.6 1 0 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 zf-MYND PF01753.13 KLO18180.1 - 2.2e-08 33.8 15.1 3.8e-08 33.0 10.4 1.4 1 0 0 1 1 1 1 MYND finger zf-Mss51 PF13824.1 KLO18180.1 - 0.55 10.1 6.9 1.3 8.9 4.8 1.6 1 0 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 zf-MYND PF01753.13 KLO18181.1 - 4.1e-08 32.9 11.3 7.3e-08 32.1 7.8 1.4 1 0 0 1 1 1 1 MYND finger Ecl1 PF12855.2 KLO18181.1 - 0.096 11.9 2.3 0.25 10.6 1.6 1.6 1 0 0 1 1 1 0 Life-span regulatory factor zf-HIT PF04438.11 KLO18181.1 - 0.31 10.7 3.5 0.56 9.9 2.4 1.4 1 0 0 1 1 1 0 HIT zinc finger zf-Mss51 PF13824.1 KLO18181.1 - 0.41 10.5 4.4 0.79 9.6 3.1 1.5 1 0 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 ADH_N PF08240.7 KLO18182.1 - 1.5e-24 85.8 3.9 3e-24 84.8 2.7 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KLO18182.1 - 9.3e-14 51.0 0.0 1.5e-13 50.4 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 KLO18182.1 - 3.4e-05 23.0 0.1 5.6e-05 22.3 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.16 KLO18182.1 - 0.012 15.1 0.0 0.022 14.3 0.0 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain ELFV_dehydrog PF00208.16 KLO18182.1 - 0.093 12.2 0.0 0.14 11.6 0.0 1.2 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase DUF1049 PF06305.6 KLO18183.1 - 0.28 10.7 1.0 0.45 10.0 0.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1049) F-box-like PF12937.2 KLO18185.1 - 0.0001 21.9 5.5 0.00018 21.1 0.1 3.6 3 1 1 4 4 4 1 F-box-like LRR_4 PF12799.2 KLO18185.1 - 0.0011 18.5 4.5 0.34 10.5 0.1 4.0 3 1 0 3 3 3 2 Leucine Rich repeats (2 copies) DUF2883 PF11097.3 KLO18185.1 - 0.058 13.5 0.0 0.12 12.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2883) F-box-like PF12937.2 KLO18186.1 - 5.4e-14 51.6 0.4 7e-05 22.4 0.0 4.3 3 0 0 3 3 3 2 F-box-like F-box PF00646.28 KLO18186.1 - 0.4 10.3 5.1 13 5.5 0.0 4.5 5 0 0 5 5 5 0 F-box domain F-box-like PF12937.2 KLO18187.1 - 0.0007 19.2 0.1 0.0024 17.5 0.0 2.1 2 0 0 2 2 2 1 F-box-like F-box-like PF12937.2 KLO18188.1 - 1.3e-06 28.0 0.1 3.5e-06 26.6 0.0 1.8 1 0 0 1 1 1 1 F-box-like F-box-like PF12937.2 KLO18189.1 - 2.7e-05 23.8 0.1 8.4e-05 22.2 0.1 2.0 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.2 KLO18189.1 - 0.54 9.9 7.0 3.7 7.2 0.1 4.6 3 2 0 3 3 3 0 Leucine Rich repeats (2 copies) F-box-like PF12937.2 KLO18190.1 - 1.3e-06 27.9 0.2 9.4e-06 25.2 0.0 2.5 2 0 0 2 2 2 1 F-box-like F-box-like PF12937.2 KLO18192.1 - 8e-06 25.4 0.1 8e-06 25.4 0.1 2.5 2 1 1 3 3 3 1 F-box-like LRR_4 PF12799.2 KLO18192.1 - 0.19 11.3 1.3 5.8 6.6 0.8 3.2 2 1 0 2 2 2 0 Leucine Rich repeats (2 copies) F-box-like PF12937.2 KLO18194.1 - 1.2e-07 31.3 0.1 5.8e-07 29.1 0.0 2.2 2 0 0 2 2 2 1 F-box-like F-box-like PF12937.2 KLO18195.1 - 7.4e-06 25.5 0.7 1.7e-05 24.4 0.0 2.0 2 0 0 2 2 2 1 F-box-like F-box-like PF12937.2 KLO18196.1 - 1.3e-07 31.2 0.2 1e-05 25.1 0.0 2.9 2 0 0 2 2 2 2 F-box-like F-box-like PF12937.2 KLO18197.1 - 5.1e-05 22.9 0.6 5.1e-05 22.9 0.4 2.5 2 0 0 2 2 2 1 F-box-like Unstab_antitox PF09720.5 KLO18197.1 - 0.05 13.2 1.2 0.095 12.4 0.0 2.0 2 0 0 2 2 2 0 Putative addiction module component F-box-like PF12937.2 KLO18199.1 - 5.1e-07 29.3 1.4 6.9e-07 28.8 0.1 2.0 2 0 0 2 2 2 1 F-box-like DEAD PF00270.24 KLO18199.1 - 0.015 14.7 0.0 0.039 13.4 0.0 1.6 2 0 0 2 2 2 0 DEAD/DEAH box helicase LRR_4 PF12799.2 KLO18199.1 - 0.26 10.9 6.2 8.4 6.1 0.4 3.9 3 1 0 3 3 3 0 Leucine Rich repeats (2 copies) F-box-like PF12937.2 KLO18200.1 - 4.2e-06 26.3 0.1 1.4e-05 24.7 0.0 1.9 1 0 0 1 1 1 1 F-box-like F-box-like PF12937.2 KLO18201.1 - 1.1e-07 31.4 0.1 3.7e-07 29.7 0.1 1.9 1 0 0 1 1 1 1 F-box-like Pkinase PF00069.20 KLO18203.1 - 6.4e-66 222.1 0.0 2e-34 118.9 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 KLO18203.1 - 2.9e-56 190.3 0.0 6.2e-27 94.2 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 KLO18203.1 - 9e-06 24.8 0.0 0.02 13.8 0.0 2.5 2 1 0 2 2 2 2 Kinase-like RIO1 PF01163.17 KLO18203.1 - 1.1e-05 24.9 0.1 0.031 13.6 0.0 2.4 2 0 0 2 2 2 2 RIO1 family APH PF01636.18 KLO18203.1 - 0.0075 16.0 0.0 0.7 9.5 0.0 2.5 2 0 0 2 2 2 1 Phosphotransferase enzyme family Lentiviral_Tat PF02998.9 KLO18203.1 - 0.075 12.8 0.6 11 5.9 0.0 2.6 2 0 0 2 2 2 0 Lentiviral Tat protein Pox_ser-thr_kin PF05445.6 KLO18203.1 - 0.078 11.7 0.0 6.6 5.4 0.0 2.1 2 0 0 2 2 2 0 Poxvirus serine/threonine protein kinase Pyr_redox_3 PF13738.1 KLO18204.1 - 1e-20 74.6 0.0 5.7e-20 72.2 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 KLO18204.1 - 6.6e-20 70.7 0.0 1.6e-18 66.2 0.0 2.6 1 1 1 2 2 2 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.1 KLO18204.1 - 3.4e-12 45.9 0.0 5.8e-08 32.0 0.0 3.1 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 KLO18204.1 - 5.6e-09 36.1 0.0 2.1e-07 31.0 0.0 2.3 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 KLO18204.1 - 5e-07 30.0 0.3 0.03 14.7 0.1 3.4 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 KLO18204.1 - 0.00023 20.3 0.1 0.011 14.7 0.1 2.8 3 0 0 3 3 3 1 FAD binding domain 2-Hacid_dh_C PF02826.14 KLO18204.1 - 0.00056 19.1 0.2 0.023 13.8 0.0 2.2 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 3HCDH_N PF02737.13 KLO18204.1 - 0.00085 19.0 0.2 0.24 11.0 0.0 2.2 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_8 PF13450.1 KLO18204.1 - 0.0021 18.0 0.0 0.014 15.3 0.0 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain SnoaL_2 PF12680.2 KLO18204.1 - 0.0033 17.7 0.5 0.015 15.7 0.0 2.2 2 0 0 2 2 2 1 SnoaL-like domain FAD_binding_2 PF00890.19 KLO18204.1 - 0.013 14.3 0.4 0.043 12.6 0.4 1.7 2 0 0 2 2 2 0 FAD binding domain DUF4440 PF14534.1 KLO18204.1 - 0.016 15.4 0.1 0.066 13.4 0.0 2.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4440) HI0933_like PF03486.9 KLO18204.1 - 0.02 13.3 0.1 0.039 12.4 0.1 1.4 1 0 0 1 1 1 0 HI0933-like protein Thi4 PF01946.12 KLO18204.1 - 0.023 13.7 0.0 0.23 10.4 0.0 2.1 2 0 0 2 2 2 0 Thi4 family GIDA PF01134.17 KLO18204.1 - 0.028 13.2 0.6 0.086 11.6 0.3 1.8 2 0 0 2 2 2 0 Glucose inhibited division protein A Shikimate_DH PF01488.15 KLO18204.1 - 0.04 14.0 0.0 9.1 6.3 0.0 3.0 3 0 0 3 3 3 0 Shikimate / quinate 5-dehydrogenase SnoaL_4 PF13577.1 KLO18204.1 - 0.055 13.3 0.2 0.24 11.3 0.0 2.0 2 0 0 2 2 2 0 SnoaL-like domain SnoaL_3 PF13474.1 KLO18204.1 - 0.066 13.2 0.2 0.13 12.2 0.2 1.5 1 0 0 1 1 1 0 SnoaL-like domain NTF2 PF02136.15 KLO18204.1 - 0.067 13.5 0.0 0.34 11.2 0.0 2.1 2 0 0 2 2 2 0 Nuclear transport factor 2 (NTF2) domain DAO PF01266.19 KLO18204.1 - 0.086 11.7 3.6 0.45 9.3 0.2 3.2 4 0 0 4 4 4 0 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 KLO18204.1 - 0.09 12.5 0.8 19 4.9 0.1 3.0 2 1 1 3 3 3 0 FAD-NAD(P)-binding Lycopene_cycl PF05834.7 KLO18204.1 - 0.1 11.4 0.3 1.8 7.4 0.1 2.8 4 0 0 4 4 4 0 Lycopene cyclase protein TrkA_N PF02254.13 KLO18204.1 - 0.22 11.5 0.7 0.53 10.3 0.1 1.9 2 0 0 2 2 2 0 TrkA-N domain FMO-like PF00743.14 KLO18206.1 - 5.9e-17 61.0 0.0 2.1e-16 59.2 0.0 1.9 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 KLO18206.1 - 3.9e-13 49.9 0.0 1.8e-12 47.7 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 KLO18206.1 - 5.6e-06 26.3 0.0 0.00088 19.2 0.0 2.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 KLO18206.1 - 2.2e-05 23.5 0.0 0.31 9.8 0.0 3.1 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox PF00070.22 KLO18206.1 - 0.00069 19.9 0.1 0.015 15.6 0.2 2.7 3 0 0 3 3 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 KLO18206.1 - 0.0012 17.9 0.0 0.0051 15.9 0.1 1.9 2 0 0 2 2 2 1 FAD binding domain DAO PF01266.19 KLO18206.1 - 0.0018 17.2 0.0 0.25 10.1 0.0 3.0 3 0 0 3 3 3 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KLO18206.1 - 0.0068 16.4 0.0 0.029 14.3 0.0 2.1 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain SnoaL_2 PF12680.2 KLO18206.1 - 0.0078 16.6 0.1 0.026 14.9 0.0 2.0 2 0 0 2 2 2 1 SnoaL-like domain DUF4440 PF14534.1 KLO18206.1 - 0.013 15.7 0.1 0.33 11.1 0.0 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4440) GIDA PF01134.17 KLO18206.1 - 0.017 14.0 0.5 0.13 11.1 0.2 2.2 2 0 0 2 2 2 0 Glucose inhibited division protein A 2-Hacid_dh_C PF02826.14 KLO18206.1 - 0.027 13.6 0.0 0.083 12.0 0.0 1.7 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain HI0933_like PF03486.9 KLO18206.1 - 0.033 12.6 0.1 0.064 11.7 0.1 1.4 1 0 0 1 1 1 0 HI0933-like protein FAD_binding_2 PF00890.19 KLO18206.1 - 0.045 12.6 0.5 0.094 11.5 0.3 1.5 1 0 0 1 1 1 0 FAD binding domain NAD_binding_9 PF13454.1 KLO18206.1 - 0.056 13.2 0.9 10 5.8 0.2 3.2 2 1 1 3 3 3 0 FAD-NAD(P)-binding Lycopene_cycl PF05834.7 KLO18206.1 - 0.075 11.9 0.0 2 7.2 0.1 2.7 3 0 0 3 3 3 0 Lycopene cyclase protein SnoaL_4 PF13577.1 KLO18206.1 - 0.13 12.1 0.5 0.41 10.5 0.0 2.0 2 0 0 2 2 2 0 SnoaL-like domain F-box-like PF12937.2 KLO18207.1 - 0.00019 21.0 0.0 0.0005 19.7 0.0 1.8 1 0 0 1 1 1 1 F-box-like F-box-like PF12937.2 KLO18208.1 - 0.00095 18.8 0.3 0.0039 16.8 0.0 2.2 2 0 0 2 2 2 1 F-box-like Flagellin_N PF00669.15 KLO18210.1 - 0.035 13.8 0.1 0.068 12.9 0.1 1.4 1 0 0 1 1 1 0 Bacterial flagellin N-terminal helical region RNaseH_C PF09293.5 KLO18211.1 - 0.086 12.7 0.3 0.11 12.4 0.2 1.3 1 0 0 1 1 1 0 T4 RNase H, C terminal F-box-like PF12937.2 KLO18213.1 - 5.4e-06 26.0 4.2 1.3e-05 24.8 0.8 2.9 2 1 0 2 2 2 1 F-box-like p450 PF00067.17 KLO18216.1 - 4.8e-61 206.6 0.0 6.5e-61 206.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Herpes_LMP1 PF05297.6 KLO18217.1 - 1.4 7.7 7.1 2.4 6.9 4.9 1.3 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) Chromate_transp PF02417.10 KLO18217.1 - 2.4 7.7 16.0 1.8 8.1 0.4 2.5 2 1 0 2 2 2 0 Chromate transporter DUF3328 PF11807.3 KLO18218.1 - 1.7e-16 60.5 0.0 2.1e-16 60.2 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) PCAF_N PF06466.6 KLO18218.1 - 0.048 12.9 0.0 0.063 12.6 0.0 1.2 1 0 0 1 1 1 0 PCAF (P300/CBP-associated factor) N-terminal domain PsbN PF02468.10 KLO18218.1 - 0.18 11.4 0.3 0.39 10.3 0.2 1.5 1 0 0 1 1 1 0 Photosystem II reaction centre N protein (psbN) DUF3328 PF11807.3 KLO18219.1 - 4.4e-19 69.0 0.2 5.7e-19 68.6 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) DUF3328 PF11807.3 KLO18222.1 - 6e-17 62.0 0.0 8.5e-17 61.5 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) F-box-like PF12937.2 KLO18223.1 - 3e-06 26.8 1.5 5.6e-05 22.7 0.2 3.1 2 1 0 2 2 2 1 F-box-like F-box-like PF12937.2 KLO18224.1 - 0.0025 17.4 3.0 0.0069 16.0 0.8 2.7 2 1 0 2 2 2 1 F-box-like vATP-synt_E PF01991.13 KLO18226.1 - 2.5e-59 199.9 11.6 2.9e-59 199.7 8.0 1.0 1 0 0 1 1 1 1 ATP synthase (E/31 kDa) subunit UPF0228 PF05727.6 KLO18226.1 - 0.048 13.4 2.5 0.089 12.5 1.8 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0228) Afaf PF15339.1 KLO18226.1 - 0.088 12.3 4.1 0.081 12.5 2.1 1.4 2 0 0 2 2 2 0 Acrosome formation-associated factor Helicase_RecD PF05127.9 KLO18226.1 - 0.17 11.5 2.1 0.15 11.7 0.3 1.6 1 1 1 2 2 2 0 Helicase RE_AlwI PF09491.5 KLO18226.1 - 0.23 9.9 7.3 0.29 9.5 5.1 1.1 1 0 0 1 1 1 0 AlwI restriction endonuclease Mgr1 PF08602.5 KLO18226.1 - 0.23 10.4 4.0 0.31 10.0 2.7 1.2 1 0 0 1 1 1 0 Mgr1-like, i-AAA protease complex subunit DUF4026 PF13218.1 KLO18226.1 - 0.27 10.0 4.1 0.41 9.4 2.8 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF4026) Alg14 PF08660.6 KLO18226.1 - 0.56 10.1 2.2 0.94 9.4 1.5 1.4 1 0 0 1 1 1 0 Oligosaccharide biosynthesis protein Alg14 like GLTP PF08718.6 KLO18226.1 - 0.86 9.6 6.2 1.9 8.5 4.3 1.6 1 1 0 1 1 1 0 Glycolipid transfer protein (GLTP) Atg14 PF10186.4 KLO18226.1 - 7.8 5.3 10.5 9.5 5.0 7.3 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 ubiquitin PF00240.18 KLO18227.1 - 2.2e-18 65.4 0.1 3.6e-18 64.7 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin family UBA PF00627.26 KLO18227.1 - 1.2e-09 37.6 0.1 1.2e-09 37.6 0.1 2.4 3 0 0 3 3 3 1 UBA/TS-N domain Rad60-SLD PF11976.3 KLO18227.1 - 4.1e-09 35.9 0.2 6.4e-09 35.3 0.1 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 KLO18227.1 - 0.00017 21.7 0.0 0.0003 20.8 0.0 1.4 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain Rad60-SLD_2 PF13881.1 KLO18227.1 - 0.039 13.8 0.0 0.075 12.9 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like NPCBM PF08305.6 KLO18227.1 - 0.11 12.4 0.0 0.21 11.5 0.0 1.5 1 0 0 1 1 1 0 NPCBM/NEW2 domain DUF302 PF03625.9 KLO18227.1 - 0.13 11.8 0.5 0.35 10.4 0.4 1.7 1 0 0 1 1 1 0 Domain of unknown function DUF302 Mss4 PF04421.8 KLO18228.1 - 3.4e-11 42.8 0.0 9.7e-11 41.3 0.0 1.8 1 0 0 1 1 1 1 Mss4 protein Acetyltransf_1 PF00583.19 KLO18228.1 - 1.1e-07 31.8 0.0 2.2e-07 30.8 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 KLO18228.1 - 2.2e-06 27.7 0.0 4.2e-06 26.8 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 KLO18228.1 - 0.00016 21.4 0.0 0.00028 20.7 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_13 PF13880.1 KLO18228.1 - 0.041 13.6 0.0 0.11 12.3 0.0 1.7 1 0 0 1 1 1 0 ESCO1/2 acetyl-transferase Acetyltransf_10 PF13673.1 KLO18228.1 - 0.042 13.9 0.0 0.073 13.2 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Dymeclin PF09742.4 KLO18228.1 - 0.051 11.6 0.0 0.12 10.4 0.0 1.3 1 1 0 1 1 1 0 Dyggve-Melchior-Clausen syndrome protein FR47 PF08445.5 KLO18228.1 - 0.06 13.1 0.0 0.29 10.9 0.0 2.1 2 1 0 2 2 2 0 FR47-like protein Glyco_hydro_16 PF00722.16 KLO18229.1 - 5.1e-05 22.6 0.0 0.00011 21.5 0.0 1.7 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 RCC1 PF00415.13 KLO18230.1 - 6.3e-21 74.3 1.6 9.9e-05 22.4 0.0 5.0 4 0 0 4 4 4 4 Regulator of chromosome condensation (RCC1) repeat BTB PF00651.26 KLO18230.1 - 4e-17 62.1 0.0 1.8e-08 34.3 0.0 3.5 2 2 1 3 3 3 2 BTB/POZ domain Ank_2 PF12796.2 KLO18230.1 - 2.6e-09 37.2 0.1 2.3e-06 27.8 0.0 2.4 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.1 KLO18230.1 - 4.2e-08 33.1 1.2 3.6e-05 23.8 0.2 3.3 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_4 PF13637.1 KLO18230.1 - 1.1e-07 32.1 1.7 1.7e-07 31.5 0.2 2.1 2 0 0 2 2 2 1 Ankyrin repeats (many copies) RCC1_2 PF13540.1 KLO18230.1 - 2.4e-07 30.1 4.8 3.8e-07 29.5 0.0 3.6 4 0 0 4 4 4 1 Regulator of chromosome condensation (RCC1) repeat Ank_3 PF13606.1 KLO18230.1 - 1.7e-06 27.7 0.4 0.0088 16.1 0.0 3.1 2 0 0 2 2 2 2 Ankyrin repeat Ank PF00023.25 KLO18230.1 - 0.00053 19.6 0.5 0.21 11.4 0.0 2.9 2 0 0 2 2 2 1 Ankyrin repeat DUF3342 PF11822.3 KLO18230.1 - 0.0027 16.9 0.4 0.0052 15.9 0.3 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3342) Ras PF00071.17 KLO18231.1 - 5.1e-34 116.9 0.1 6.2e-34 116.7 0.1 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KLO18231.1 - 3.3e-22 79.1 0.1 9.5e-22 77.7 0.0 1.7 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 KLO18231.1 - 6.8e-08 31.9 0.0 9.3e-08 31.5 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 KLO18231.1 - 2.3e-07 30.1 0.2 3e-07 29.8 0.1 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region G-alpha PF00503.15 KLO18231.1 - 0.01 14.5 0.7 0.042 12.5 0.0 2.0 1 1 1 2 2 2 0 G-protein alpha subunit MMR_HSR1 PF01926.18 KLO18231.1 - 0.011 15.7 0.0 0.022 14.6 0.0 1.5 1 1 0 1 1 1 0 50S ribosome-binding GTPase DLIC PF05783.6 KLO18231.1 - 0.024 13.2 0.7 1.6 7.3 0.1 2.2 2 1 0 2 2 2 0 Dynein light intermediate chain (DLIC) CD24 PF14984.1 KLO18231.1 - 1.9 8.3 9.6 3.7 7.4 6.7 1.5 1 0 0 1 1 1 0 CD24 protein Aldo_ket_red PF00248.16 KLO18232.1 - 4.2e-52 176.7 0.0 5.1e-52 176.4 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family F-box-like PF12937.2 KLO18233.1 - 0.00027 20.6 0.5 0.00068 19.3 0.3 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KLO18233.1 - 0.00069 19.2 1.3 0.00069 19.2 0.9 2.2 2 0 0 2 2 2 1 F-box domain Zn_clus PF00172.13 KLO18236.1 - 4.3e-08 32.9 11.3 7.9e-08 32.0 7.9 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 KLO18236.1 - 1.4e-05 24.1 0.0 2.7e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Copper-fist PF00649.13 KLO18236.1 - 0.31 10.2 5.6 0.043 13.0 0.4 2.2 1 1 1 2 2 2 0 Copper fist DNA binding domain Tbf5 PF06331.7 KLO18237.1 - 5.5e-19 67.7 0.7 5.8e-19 67.6 0.5 1.0 1 0 0 1 1 1 1 Transcription factor TFIIH complex subunit Tfb5 MotCF PF09158.5 KLO18237.1 - 0.013 15.1 0.4 0.015 14.9 0.3 1.1 1 0 0 1 1 1 0 Bacteriophage T4 MotA, C-terminal ERGIC_N PF13850.1 KLO18237.1 - 0.094 12.6 0.0 0.1 12.5 0.0 1.0 1 0 0 1 1 1 0 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) Rib_5-P_isom_A PF06026.9 KLO18238.1 - 2.4e-54 183.2 0.0 3e-54 182.9 0.0 1.1 1 0 0 1 1 1 1 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) DeoRC PF00455.17 KLO18238.1 - 0.065 12.8 0.0 4.9 6.7 0.0 2.1 1 1 1 2 2 2 0 DeoR C terminal sensor domain Peptidase_M50 PF02163.17 KLO18240.1 - 9.9e-07 27.9 0.9 6.5e-06 25.2 0.1 2.0 2 0 0 2 2 2 2 Peptidase family M50 HNH_2 PF13391.1 KLO18241.1 - 1.9e-08 33.9 0.0 4.3e-08 32.8 0.0 1.6 1 0 0 1 1 1 1 HNH endonuclease Peptidase_M50 PF02163.17 KLO18242.1 - 3.5e-06 26.1 1.0 1.2e-05 24.3 0.1 1.9 2 0 0 2 2 2 1 Peptidase family M50 NPR3 PF03666.8 KLO18243.1 - 6.3e-55 186.4 1.0 2.4e-45 154.9 0.0 3.8 1 1 1 2 2 2 2 Nitrogen Permease regulator of amino acid transport activity 3 HTH_28 PF13518.1 KLO18243.1 - 0.044 13.7 0.0 0.12 12.3 0.0 1.8 1 0 0 1 1 1 0 Helix-turn-helix domain Glyco_hydro_18 PF00704.23 KLO18244.1 - 5.4e-11 42.5 0.6 6.9e-11 42.1 0.4 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Glyco_hydro_18 PF00704.23 KLO18245.1 - 1.1e-85 288.1 9.8 1.1e-85 288.1 6.8 1.5 2 0 0 2 2 2 1 Glycosyl hydrolases family 18 CBM_5_12 PF02839.9 KLO18245.1 - 4.8e-10 38.8 14.7 4.8e-10 38.8 10.2 2.2 2 0 0 2 2 2 1 Carbohydrate binding domain rRNA_proc-arch PF13234.1 KLO18246.1 - 1e-94 316.6 1.0 1.3e-94 316.3 0.0 1.6 2 0 0 2 2 2 1 rRNA-processing arch domain DSHCT PF08148.7 KLO18246.1 - 5.8e-61 204.8 1.7 5.8e-61 204.8 1.2 1.7 2 0 0 2 2 2 1 DSHCT (NUC185) domain DEAD PF00270.24 KLO18246.1 - 7.2e-22 77.6 0.6 4.1e-21 75.1 0.1 2.4 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KLO18246.1 - 3.4e-07 30.0 0.0 7.8e-07 28.8 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain T2SE PF00437.15 KLO18246.1 - 0.0041 16.0 0.0 0.013 14.4 0.0 1.8 1 0 0 1 1 1 1 Type II/IV secretion system protein PhoH PF02562.11 KLO18246.1 - 0.018 14.2 0.0 0.31 10.2 0.0 2.5 2 0 0 2 2 2 0 PhoH-like protein ResIII PF04851.10 KLO18246.1 - 0.035 13.9 0.1 0.38 10.5 0.0 2.4 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_19 PF13245.1 KLO18246.1 - 0.12 12.1 0.0 0.32 10.7 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain Pkinase PF00069.20 KLO18247.1 - 2.1e-71 240.1 0.0 2.9e-71 239.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KLO18247.1 - 1.9e-34 118.9 0.0 2.6e-34 118.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.19 KLO18247.1 - 1.9e-10 41.0 1.5 4.2e-10 39.9 1.1 1.6 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.1 KLO18247.1 - 0.0017 17.3 0.0 0.0037 16.2 0.0 1.5 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 KLO18247.1 - 0.066 12.9 0.0 0.14 11.8 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.9 KLO18247.1 - 0.079 12.0 0.0 0.15 11.1 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family GATase PF00117.23 KLO18248.1 - 5.3e-11 42.3 0.0 3e-09 36.5 0.0 2.1 2 0 0 2 2 2 2 Glutamine amidotransferase class-I Spc97_Spc98 PF04130.8 KLO18249.1 - 1.8e-100 336.8 0.0 3.1e-100 336.0 0.0 1.4 1 0 0 1 1 1 1 Spc97 / Spc98 family F-box PF00646.28 KLO18251.1 - 1.1e-05 24.9 0.1 3.9e-05 23.1 0.1 1.9 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 KLO18251.1 - 1.3e-05 24.8 0.1 3.8e-05 23.3 0.0 1.9 1 0 0 1 1 1 1 F-box-like S4 PF01479.20 KLO18252.1 - 1.8e-11 43.2 0.1 2.9e-11 42.6 0.0 1.3 1 0 0 1 1 1 1 S4 domain S4_2 PF13275.1 KLO18252.1 - 0.0023 17.4 0.0 0.0041 16.6 0.0 1.4 1 0 0 1 1 1 1 S4 domain SNARE PF05739.14 KLO18253.1 - 2e-09 37.0 0.9 2e-09 37.0 0.6 2.1 3 0 0 3 3 3 1 SNARE domain Paf67 PF10255.4 KLO18254.1 - 5.4e-141 470.1 0.0 7e-141 469.7 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase I-associated factor PAF67 GLTSCR1 PF15249.1 KLO18254.1 - 0.0052 16.8 0.0 2.9 8.0 0.0 3.4 3 0 0 3 3 3 1 Glioma tumor suppressor candidate region PAP_assoc PF03828.14 KLO18255.1 - 9.7e-08 31.8 0.1 0.0001 22.1 0.0 4.2 4 0 0 4 4 4 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.18 KLO18255.1 - 8e-05 22.8 0.0 0.00019 21.6 0.0 1.6 1 0 0 1 1 1 1 Nucleotidyltransferase domain tRNA_NucTransf2 PF09249.6 KLO18255.1 - 0.00043 20.1 0.0 0.28 11.0 0.0 2.5 2 0 0 2 2 2 2 tRNA nucleotidyltransferase, second domain HTH_33 PF13592.1 KLO18255.1 - 0.022 14.2 0.1 9.4 5.8 0.1 3.3 3 0 0 3 3 3 0 Winged helix-turn helix GATase PF00117.23 KLO18257.1 - 1.6e-09 37.4 0.0 6.7e-09 35.4 0.0 1.8 1 1 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.8 KLO18257.1 - 0.02 14.3 0.0 0.054 12.9 0.0 1.9 1 1 0 1 1 1 0 Peptidase C26 HTS PF04204.11 KLO18257.1 - 0.049 12.3 0.0 0.14 10.8 0.0 1.6 2 0 0 2 2 2 0 Homoserine O-succinyltransferase Glyco_hydro_16 PF00722.16 KLO18259.1 - 0.00039 19.7 0.0 0.00092 18.5 0.0 1.7 2 0 0 2 2 2 1 Glycosyl hydrolases family 16 DUF3317 PF11779.3 KLO18261.1 - 5.3e-09 35.3 3.8 7.1e-09 34.9 2.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3317) DUF2636 PF11120.3 KLO18261.1 - 0.031 13.7 1.7 0.61 9.6 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2636) Plasmod_dom_1 PF09715.5 KLO18261.1 - 0.084 12.8 0.3 0.13 12.2 0.2 1.3 1 0 0 1 1 1 0 Plasmodium protein of unknown function (Plasmod_dom_1) FtsX PF02687.16 KLO18261.1 - 0.11 12.2 2.8 0.14 11.8 2.0 1.2 1 0 0 1 1 1 0 FtsX-like permease family DUF4481 PF14800.1 KLO18261.1 - 0.22 10.3 2.6 0.28 10.0 1.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4481) Methyltransf_11 PF08241.7 KLO18265.1 - 1.6e-17 63.7 0.0 2.9e-17 62.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KLO18265.1 - 7.5e-11 42.2 0.0 1.4e-10 41.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KLO18265.1 - 3.8e-10 40.3 0.0 8.4e-10 39.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KLO18265.1 - 5.1e-08 32.6 0.0 9.3e-08 31.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KLO18265.1 - 5.7e-08 33.1 0.0 1.5e-07 31.7 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KLO18265.1 - 3.4e-05 23.6 0.0 5.4e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 KLO18265.1 - 0.00013 21.2 0.0 0.00017 20.7 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_26 PF13659.1 KLO18265.1 - 0.012 15.6 0.0 0.024 14.6 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_4 PF02390.12 KLO18265.1 - 0.11 11.5 0.0 0.19 10.7 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase Glyco_hydro_18 PF00704.23 KLO18266.1 - 1.1e-08 34.8 4.1 2e-08 34.0 2.8 1.3 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 SBP_bac_7 PF03480.8 KLO18266.1 - 0.02 14.0 0.0 0.028 13.5 0.0 1.2 1 0 0 1 1 1 0 Bacterial extracellular solute-binding protein, family 7 GCN5L1 PF06320.8 KLO18267.1 - 0.0071 16.1 0.1 0.012 15.3 0.1 1.4 1 0 0 1 1 1 1 GCN5-like protein 1 (GCN5L1) Actin PF00022.14 KLO18272.1 - 8.6e-97 324.0 0.0 1e-96 323.7 0.0 1.1 1 0 0 1 1 1 1 Actin MreB_Mbl PF06723.8 KLO18272.1 - 0.00041 19.0 0.0 0.6 8.6 0.0 2.7 3 0 0 3 3 3 2 MreB/Mbl protein PilM_2 PF11104.3 KLO18272.1 - 0.004 16.0 0.0 0.11 11.3 0.0 2.1 2 0 0 2 2 2 1 Type IV pilus assembly protein PilM; AAA_17 PF13207.1 KLO18273.1 - 1.6e-14 54.7 0.0 2e-14 54.4 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 KLO18273.1 - 6.6e-05 23.2 0.0 0.00012 22.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain SKI PF01202.17 KLO18273.1 - 0.017 14.9 0.0 0.056 13.3 0.0 1.9 1 1 0 1 1 1 0 Shikimate kinase NB-ARC PF00931.17 KLO18273.1 - 0.11 11.3 0.0 0.16 10.8 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain AAA_33 PF13671.1 KLO18273.1 - 0.13 12.1 0.0 0.2 11.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain DUF4293 PF14126.1 KLO18275.1 - 0.27 11.1 2.5 1 9.2 0.4 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4293) Claudin_2 PF13903.1 KLO18275.1 - 3.7 7.2 8.8 1 9.0 1.0 2.4 1 1 1 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction NEP PF10167.4 KLO18277.1 - 0.14 11.8 0.0 2.1 8.0 0.0 2.2 2 0 0 2 2 2 0 Uncharacterised conserved protein NACHT PF05729.7 KLO18278.1 - 3.8e-08 33.1 0.0 1.6e-07 31.1 0.0 2.1 2 0 0 2 2 2 1 NACHT domain PhoH PF02562.11 KLO18278.1 - 0.068 12.4 0.0 0.13 11.4 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein AAA_22 PF13401.1 KLO18278.1 - 0.11 12.6 0.0 0.35 11.0 0.0 1.9 1 0 0 1 1 1 0 AAA domain HTH_Mga PF08280.6 KLO18278.1 - 0.14 11.9 0.7 4.3 7.1 0.0 2.5 2 0 0 2 2 2 0 M protein trans-acting positive regulator (MGA) HTH domain AAA_17 PF13207.1 KLO18279.1 - 1.9e-10 41.5 0.0 2.4e-10 41.2 0.0 1.2 1 0 0 1 1 1 1 AAA domain Myosin_head PF00063.16 KLO18281.1 - 3e-240 798.9 0.0 1.4e-239 796.7 0.0 2.3 1 0 0 1 1 1 1 Myosin head (motor domain) Myosin_tail_1 PF01576.14 KLO18281.1 - 4e-14 51.3 285.2 7.3e-08 30.6 37.9 8.3 2 2 3 5 5 5 4 Myosin tail Myosin_N PF02736.14 KLO18281.1 - 3.8e-07 29.6 5.7 9.8e-07 28.3 3.9 1.7 1 0 0 1 1 1 1 Myosin N-terminal SH3-like domain Chromo PF00385.19 KLO18284.1 - 8.3e-05 22.1 2.6 0.00041 19.9 1.8 2.3 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain FAD_binding_3 PF01494.14 KLO18285.1 - 0.0064 15.5 0.0 0.012 14.6 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain DUF3088 PF11287.3 KLO18285.1 - 0.13 11.7 0.0 0.37 10.2 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3088) DIM PF08194.7 KLO18287.1 - 0.11 12.4 0.9 0.18 11.7 0.6 1.3 1 0 0 1 1 1 0 DIM protein Rubredoxin PF00301.15 KLO18287.1 - 4.8 7.1 13.8 9.2 6.2 0.6 3.2 1 1 2 3 3 3 0 Rubredoxin Shadoo PF14999.1 KLO18287.1 - 9.5 6.0 8.3 3.1 7.6 2.5 2.4 1 1 1 2 2 2 0 Shadow of prion protein, neuroprotective Peptidase_M14 PF00246.19 KLO18288.1 - 3.9e-59 200.5 0.0 5.2e-59 200.1 0.0 1.2 1 0 0 1 1 1 1 Zinc carboxypeptidase ATG13 PF10033.4 KLO18289.1 - 4.7e-29 101.4 0.0 7.1e-29 100.8 0.0 1.3 1 0 0 1 1 1 1 Autophagy-related protein 13 ADH_N PF08240.7 KLO18290.1 - 3.9e-30 103.8 0.4 3.9e-30 103.8 0.3 2.0 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KLO18290.1 - 9.1e-13 47.8 0.0 1.7e-12 47.0 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase FAD_binding_3 PF01494.14 KLO18290.1 - 0.00016 20.8 0.0 0.00023 20.3 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain ADH_N_assoc PF13823.1 KLO18290.1 - 0.00037 20.0 0.1 0.00082 18.9 0.0 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-associated ADH_zinc_N_2 PF13602.1 KLO18290.1 - 0.00067 20.5 0.0 0.0012 19.7 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Shikimate_DH PF01488.15 KLO18290.1 - 0.0014 18.7 0.0 0.0027 17.8 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NAD_binding_8 PF13450.1 KLO18290.1 - 0.096 12.7 0.0 0.35 10.9 0.0 2.0 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 KLO18290.1 - 0.13 12.1 0.0 0.24 11.2 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase tRNA-synt_1c_C PF03950.13 KLO18290.1 - 0.13 11.8 0.0 0.25 11.0 0.0 1.3 1 0 0 1 1 1 0 tRNA synthetases class I (E and Q), anti-codon binding domain HAD_2 PF13419.1 KLO18293.1 - 1.7e-16 60.9 0.3 2.1e-15 57.3 0.2 2.1 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 KLO18293.1 - 0.013 15.2 0.0 0.021 14.5 0.0 1.3 1 0 0 1 1 1 0 HAD-hyrolase-like Hydrolase PF00702.21 KLO18293.1 - 0.029 14.7 0.0 0.095 13.0 0.0 1.8 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase Ribosomal_L38e PF01781.13 KLO18295.1 - 1.9e-16 59.5 2.2 2.2e-16 59.3 1.5 1.1 1 0 0 1 1 1 1 Ribosomal L38e protein family DSBA PF01323.15 KLO18296.1 - 1.8e-34 118.9 0.2 2.1e-34 118.7 0.1 1.0 1 0 0 1 1 1 1 DSBA-like thioredoxin domain Thioredoxin_3 PF13192.1 KLO18296.1 - 6.9e-05 22.5 0.1 0.0068 16.2 0.0 2.3 2 0 0 2 2 2 1 Thioredoxin domain Thioredoxin_2 PF13098.1 KLO18296.1 - 0.00012 22.1 0.1 0.0095 16.1 0.0 2.2 2 0 0 2 2 2 1 Thioredoxin-like domain Thioredoxin_4 PF13462.1 KLO18296.1 - 0.0022 17.9 0.4 0.0086 16.0 0.3 1.9 1 1 0 1 1 1 1 Thioredoxin DUF1525 PF07511.6 KLO18296.1 - 0.0046 16.9 0.1 0.0078 16.2 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1525) PmbA_TldD PF01523.11 KLO18296.1 - 0.012 14.9 0.0 0.015 14.5 0.0 1.1 1 0 0 1 1 1 0 Putative modulator of DNA gyrase GFA PF04828.9 KLO18297.1 - 8.8e-11 41.6 0.4 1.3e-10 41.0 0.3 1.3 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme Zn_Tnp_IS1595 PF12760.2 KLO18297.1 - 0.18 11.6 0.2 0.18 11.6 0.1 2.2 2 0 0 2 2 2 0 Transposase zinc-ribbon domain Sgf11 PF08209.6 KLO18297.1 - 0.46 9.8 8.3 0.71 9.2 1.4 2.9 3 0 0 3 3 3 0 Sgf11 (transcriptional regulation protein) CBM_20 PF00686.14 KLO18298.1 - 1.8e-33 114.0 0.7 4.6e-33 112.6 0.5 1.7 1 0 0 1 1 1 1 Starch binding domain Alpha-amylase PF00128.19 KLO18298.1 - 3.1e-14 53.1 0.0 6.6e-14 52.0 0.0 1.4 1 1 0 1 1 1 1 Alpha amylase, catalytic domain Alpha-amylase_C PF02806.13 KLO18298.1 - 1.1e-11 44.7 0.1 3.7e-11 43.0 0.0 2.0 2 0 0 2 2 2 1 Alpha amylase, C-terminal all-beta domain RRM_1 PF00076.17 KLO18300.1 - 5.5e-57 189.3 0.0 2.8e-15 55.6 0.0 5.9 6 0 0 6 6 6 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KLO18300.1 - 4.3e-44 148.3 0.0 4.1e-12 45.8 0.0 5.4 5 0 0 5 5 5 5 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KLO18300.1 - 2.5e-16 59.2 0.0 0.0056 16.4 0.0 5.3 5 0 0 5 5 5 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 KLO18300.1 - 0.057 13.1 0.0 8.4 6.2 0.0 3.5 4 0 0 4 4 4 0 Nup53/35/40-type RNA recognition motif MFS_1 PF07690.11 KLO18301.1 - 8.4e-23 80.6 44.1 2.5e-19 69.2 20.2 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily CoA_binding_3 PF13727.1 KLO18301.1 - 0.58 9.9 3.7 0.42 10.4 0.8 2.2 2 0 0 2 2 2 0 CoA-binding domain ATP1G1_PLM_MAT8 PF02038.11 KLO18301.1 - 1.6 7.7 4.7 2.9 6.9 0.2 2.5 2 0 0 2 2 2 0 ATP1G1/PLM/MAT8 family ABC2_membrane PF01061.19 KLO18303.1 - 1.2e-69 233.7 52.1 3.2e-39 134.2 9.8 3.0 4 0 0 4 4 3 2 ABC-2 type transporter ABC_tran PF00005.22 KLO18303.1 - 3.3e-38 131.0 0.0 7.8e-19 68.3 0.0 2.4 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.7 KLO18303.1 - 2.3e-34 117.1 1.3 5.5e-27 93.4 0.0 3.0 2 0 0 2 2 2 2 CDR ABC transporter AAA_22 PF13401.1 KLO18303.1 - 2.6e-08 34.0 0.0 0.00048 20.2 0.0 3.1 2 1 0 2 2 2 2 AAA domain ABC_trans_N PF14510.1 KLO18303.1 - 1.5e-06 28.1 0.0 3.7e-06 26.9 0.0 1.7 1 0 0 1 1 1 1 ABC-transporter extracellular N-terminal AAA_25 PF13481.1 KLO18303.1 - 2.8e-06 26.8 0.1 0.012 14.9 0.1 2.5 2 0 0 2 2 2 2 AAA domain DUF258 PF03193.11 KLO18303.1 - 3e-06 26.5 0.1 0.00014 21.0 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_21 PF13304.1 KLO18303.1 - 3.3e-05 23.9 0.0 0.21 11.5 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.1 KLO18303.1 - 5.7e-05 23.1 4.1 0.22 11.4 0.5 3.5 3 2 0 3 3 3 2 AAA ATPase domain AAA_29 PF13555.1 KLO18303.1 - 0.00019 20.8 0.5 0.076 12.5 0.0 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain MMR_HSR1 PF01926.18 KLO18303.1 - 0.0016 18.3 0.0 0.91 9.5 0.0 2.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_18 PF13238.1 KLO18303.1 - 0.0028 17.9 0.0 2.7 8.2 0.0 2.7 2 0 0 2 2 2 1 AAA domain NACHT PF05729.7 KLO18303.1 - 0.0037 16.9 0.5 1.4 8.5 0.2 2.7 2 0 0 2 2 2 1 NACHT domain Miro PF08477.8 KLO18303.1 - 0.0066 16.9 0.0 2.5 8.6 0.0 2.5 2 0 0 2 2 2 1 Miro-like protein AAA_33 PF13671.1 KLO18303.1 - 0.0067 16.3 0.0 2.8 7.7 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_10 PF12846.2 KLO18303.1 - 0.007 15.8 0.5 3 7.1 0.2 2.5 2 0 0 2 2 2 1 AAA-like domain cobW PF02492.14 KLO18303.1 - 0.0084 15.5 2.4 0.4 10.1 0.3 2.6 3 0 0 3 3 2 1 CobW/HypB/UreG, nucleotide-binding domain SbcCD_C PF13558.1 KLO18303.1 - 0.017 15.0 0.0 1.2 9.1 0.0 2.7 2 0 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_30 PF13604.1 KLO18303.1 - 0.017 14.7 0.1 1.3 8.5 0.1 2.5 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.1 KLO18303.1 - 0.017 15.0 0.1 0.94 9.4 0.1 2.5 2 0 0 2 2 2 0 AAA domain FtsK_SpoIIIE PF01580.13 KLO18303.1 - 0.017 14.5 0.0 1.2 8.5 0.0 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_19 PF13245.1 KLO18303.1 - 0.017 14.8 0.5 2.8 7.7 0.1 2.8 2 0 0 2 2 2 0 Part of AAA domain AAA_17 PF13207.1 KLO18303.1 - 0.021 15.6 0.0 3.4 8.5 0.0 2.6 2 0 0 2 2 2 0 AAA domain ABC2_membrane_3 PF12698.2 KLO18303.1 - 0.03 13.3 44.6 0.35 9.8 14.0 3.0 2 2 1 3 3 3 0 ABC-2 family transporter protein AAA PF00004.24 KLO18303.1 - 0.041 14.0 0.0 18 5.5 0.0 2.7 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Septin PF00735.13 KLO18303.1 - 0.048 12.6 0.0 9.2 5.1 0.0 2.2 2 0 0 2 2 2 0 Septin T2SE PF00437.15 KLO18303.1 - 0.06 12.2 0.0 3.4 6.4 0.0 2.2 2 0 0 2 2 2 0 Type II/IV secretion system protein PduV-EutP PF10662.4 KLO18303.1 - 0.067 12.6 0.5 1.2 8.6 0.1 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation SMC_N PF02463.14 KLO18303.1 - 0.077 12.2 0.0 1.2 8.3 0.0 2.5 3 0 0 3 3 3 0 RecF/RecN/SMC N terminal domain UPF0079 PF02367.12 KLO18303.1 - 0.086 12.4 1.2 0.84 9.2 0.3 2.3 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 Dynamin_N PF00350.18 KLO18303.1 - 0.13 12.0 0.0 0.32 10.8 0.0 1.7 2 0 0 2 2 1 0 Dynamin family DUF87 PF01935.12 KLO18303.1 - 0.26 11.0 0.2 34 4.1 0.0 2.9 3 0 0 3 3 3 0 Domain of unknown function DUF87 AAA_23 PF13476.1 KLO18303.1 - 0.38 11.0 0.3 1 9.6 0.0 1.7 2 0 0 2 2 1 0 AAA domain FeoB_N PF02421.13 KLO18303.1 - 0.41 9.9 1.2 5.1 6.3 0.1 2.8 3 0 0 3 3 3 0 Ferrous iron transport protein B AAA_15 PF13175.1 KLO18303.1 - 0.89 8.5 0.0 12 4.7 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain zf-C2H2 PF00096.21 KLO18304.1 - 0.3 11.5 7.0 0.15 12.4 2.8 2.2 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KLO18304.1 - 0.37 11.2 4.6 0.95 9.9 3.2 1.7 1 0 0 1 1 1 0 C2H2-type zinc finger Ribonuclease PF00545.15 KLO18305.1 - 1.3e-13 50.7 0.1 1.6e-13 50.4 0.0 1.1 1 0 0 1 1 1 1 ribonuclease FAD_binding_3 PF01494.14 KLO18306.1 - 3.7e-14 52.5 0.0 6.4e-14 51.7 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 KLO18306.1 - 2.1e-06 26.8 0.3 0.025 13.5 0.0 2.4 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KLO18306.1 - 0.00013 21.8 0.3 0.00028 20.8 0.2 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 KLO18306.1 - 0.0027 16.6 0.7 0.0046 15.8 0.5 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.22 KLO18306.1 - 0.013 15.8 0.1 0.044 14.1 0.1 1.9 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 KLO18306.1 - 0.025 14.4 0.4 0.05 13.4 0.2 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 KLO18306.1 - 0.033 12.6 0.1 0.074 11.5 0.1 1.5 1 0 0 1 1 1 0 HI0933-like protein FAD_oxidored PF12831.2 KLO18306.1 - 0.046 12.8 0.3 0.046 12.8 0.2 2.1 2 0 0 2 2 2 0 FAD dependent oxidoreductase Pkinase PF00069.20 KLO18308.1 - 3.5e-46 157.4 0.0 4.9e-46 156.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KLO18308.1 - 2.5e-42 144.7 0.0 3.7e-42 144.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KLO18308.1 - 0.025 13.5 0.0 0.046 12.6 0.0 1.3 1 0 0 1 1 1 0 Kinase-like RIO1 PF01163.17 KLO18308.1 - 0.039 13.3 0.0 0.67 9.2 0.0 2.0 2 0 0 2 2 2 0 RIO1 family ATG13 PF10033.4 KLO18309.1 - 6e-14 52.0 0.0 7.6e-14 51.7 0.0 1.1 1 0 0 1 1 1 1 Autophagy-related protein 13 Abhydrolase_2 PF02230.11 KLO18310.1 - 6.9e-58 195.6 0.0 4.4e-57 193.0 0.0 1.8 1 1 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_5 PF12695.2 KLO18310.1 - 2.1e-10 40.5 0.0 3.3e-10 39.8 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KLO18310.1 - 1.4e-06 28.3 0.0 7.7e-06 25.9 0.0 2.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family FSH1 PF03959.8 KLO18310.1 - 0.0022 17.4 0.0 0.0045 16.4 0.0 1.6 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Esterase PF00756.15 KLO18310.1 - 0.051 12.9 0.0 0.057 12.8 0.0 1.3 1 1 0 1 1 1 0 Putative esterase Lipase_3 PF01764.20 KLO18310.1 - 0.059 12.9 0.0 0.095 12.3 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) Trp_halogenase PF04820.9 KLO18311.1 - 2e-30 105.8 0.4 3.6e-16 58.8 0.3 2.3 1 1 1 2 2 2 2 Tryptophan halogenase FAD_binding_3 PF01494.14 KLO18311.1 - 2.8e-14 52.9 1.2 4.6e-13 48.9 0.8 2.3 1 1 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.2 KLO18311.1 - 1.3e-08 34.3 0.0 2e-08 33.7 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase DAO PF01266.19 KLO18311.1 - 2.1e-08 33.4 0.1 0.0054 15.6 0.0 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 KLO18311.1 - 1.9e-05 24.6 0.0 4.3e-05 23.4 0.0 1.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KLO18311.1 - 0.0012 18.7 0.1 0.0038 17.2 0.1 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain GIDA PF01134.17 KLO18311.1 - 0.002 17.0 0.0 0.004 16.0 0.0 1.5 1 0 0 1 1 1 1 Glucose inhibited division protein A HI0933_like PF03486.9 KLO18311.1 - 0.015 13.8 0.1 0.026 12.9 0.0 1.3 1 0 0 1 1 1 0 HI0933-like protein FAD_binding_2 PF00890.19 KLO18311.1 - 0.019 13.8 0.0 0.033 13.0 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain Thi4 PF01946.12 KLO18311.1 - 0.019 14.0 0.0 0.054 12.5 0.0 1.7 1 0 0 1 1 1 0 Thi4 family ThiF PF00899.16 KLO18311.1 - 0.043 13.6 0.1 0.13 12.0 0.1 1.8 1 0 0 1 1 1 0 ThiF family EBP PF05241.7 KLO18312.1 - 2.1e-07 30.1 12.1 2.8e-07 29.7 8.4 1.1 1 0 0 1 1 1 1 Emopamil binding protein Rab15_effector PF15208.1 KLO18313.1 - 0.11 11.9 0.0 1.6 8.1 0.0 2.0 2 0 0 2 2 2 0 Rab15 effector Phosducin PF02114.11 KLO18317.1 - 4.4e-11 42.0 0.0 1.2e-05 24.2 0.0 2.3 2 1 0 2 2 2 2 Phosducin adh_short PF00106.20 KLO18318.1 - 1.7e-28 99.6 0.3 2.1e-28 99.3 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KLO18318.1 - 4.4e-26 92.1 0.1 5.9e-26 91.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KLO18318.1 - 1.5e-12 47.5 0.2 2.3e-12 46.9 0.2 1.3 1 0 0 1 1 1 1 KR domain 3Beta_HSD PF01073.14 KLO18318.1 - 0.0028 16.4 0.4 0.0047 15.6 0.3 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family 3HCDH_N PF02737.13 KLO18318.1 - 0.011 15.3 0.1 0.018 14.6 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain RNA_pol_Rpb2_3 PF04565.11 KLO18320.1 - 0.056 13.2 0.1 0.31 10.8 0.1 2.1 2 0 0 2 2 2 0 RNA polymerase Rpb2, domain 3 GPI-anchored PF10342.4 KLO18321.1 - 5.7e-09 36.3 0.6 5.7e-09 36.3 0.4 2.1 2 0 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family F-box-like PF12937.2 KLO18323.1 - 0.0026 17.4 0.4 0.023 14.3 0.1 2.7 2 1 0 2 2 2 1 F-box-like Fungal_trans PF04082.13 KLO18324.1 - 3.4e-08 32.6 0.6 5.9e-08 31.9 0.1 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KLO18324.1 - 4.8e-06 26.3 11.1 9.2e-06 25.4 7.7 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TSC22 PF01166.13 KLO18324.1 - 0.021 14.7 0.4 0.11 12.5 0.2 2.2 2 0 0 2 2 2 0 TSC-22/dip/bun family RHD3 PF05879.7 KLO18325.1 - 5.3e-247 821.4 6.1 6.8e-247 821.1 4.2 1.1 1 0 0 1 1 1 1 Root hair defective 3 GTP-binding protein (RHD3) GBP PF02263.14 KLO18325.1 - 4.9e-07 29.0 0.2 1.4e-06 27.6 0.1 1.8 1 0 0 1 1 1 1 Guanylate-binding protein, N-terminal domain Dynamin_N PF00350.18 KLO18325.1 - 2.4e-05 24.2 0.0 5.9e-05 22.9 0.0 1.7 1 0 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.18 KLO18325.1 - 0.0001 22.2 0.0 0.00031 20.6 0.0 1.9 1 0 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 KLO18325.1 - 0.00015 22.2 0.0 0.00043 20.7 0.0 1.8 1 0 0 1 1 1 1 Miro-like protein AAA_28 PF13521.1 KLO18325.1 - 0.0015 18.5 0.1 0.0062 16.5 0.0 2.2 2 0 0 2 2 2 1 AAA domain AMP-binding PF00501.23 KLO18326.1 - 1e-67 228.3 0.0 2.1e-67 227.3 0.0 1.4 2 0 0 2 2 2 1 AMP-binding enzyme ECH PF00378.15 KLO18326.1 - 2.8e-43 147.7 0.1 4.3e-43 147.2 0.1 1.3 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family AMP-binding_C PF13193.1 KLO18326.1 - 7.2e-13 49.2 0.1 1.5e-12 48.3 0.0 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain ECH_C PF13766.1 KLO18326.1 - 0.062 13.4 0.8 2.3 8.3 0.1 2.5 2 0 0 2 2 2 0 2-enoyl-CoA Hydratase C-terminal region GH3 PF03321.8 KLO18326.1 - 0.22 10.0 0.2 5.4 5.4 0.0 2.4 2 0 0 2 2 2 0 GH3 auxin-responsive promoter Fungal_trans PF04082.13 KLO18327.1 - 1.1e-27 96.6 0.0 1.7e-27 95.9 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KLO18327.1 - 2.1e-06 27.5 7.5 2.1e-06 27.5 5.2 1.7 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HlyD PF00529.15 KLO18327.1 - 0.0027 17.0 3.3 0.0064 15.8 2.3 1.6 1 0 0 1 1 1 1 HlyD family secretion protein R3H PF01424.17 KLO18329.1 - 5.6e-11 41.9 0.0 1.4e-10 40.7 0.0 1.7 1 0 0 1 1 1 1 R3H domain G-patch PF01585.18 KLO18329.1 - 1.3e-07 31.2 0.6 3.6e-07 29.8 0.4 1.8 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.2 KLO18329.1 - 0.00098 18.9 0.4 0.00098 18.9 0.3 3.1 4 0 0 4 4 4 1 DExH-box splicing factor binding site FA_hydroxylase PF04116.8 KLO18330.1 - 2.7e-20 72.8 15.4 4.6e-20 72.1 5.9 2.3 2 1 0 2 2 2 2 Fatty acid hydroxylase superfamily HSP20 PF00011.16 KLO18331.1 - 0.0078 16.0 0.0 0.12 12.2 0.0 2.1 1 1 0 1 1 1 1 Hsp20/alpha crystallin family SynMuv_product PF06047.6 KLO18332.1 - 2.6e-42 142.8 2.5 2.6e-42 142.8 1.7 2.8 3 1 0 3 3 3 1 Ras-induced vulval development antagonist FKBP_C PF00254.23 KLO18333.1 - 8.2e-33 112.3 0.0 1e-32 112.0 0.0 1.1 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase Ribosomal_L39 PF00832.15 KLO18334.1 - 2.2e-22 78.2 7.6 2.5e-22 78.0 5.3 1.1 1 0 0 1 1 1 1 Ribosomal L39 protein FAT PF02259.18 KLO18336.1 - 1.7e-111 372.5 11.5 4.9e-111 371.1 7.9 1.8 1 0 0 1 1 1 1 FAT domain PI3_PI4_kinase PF00454.22 KLO18336.1 - 4.5e-55 186.6 0.2 1e-54 185.4 0.2 1.7 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase DUF3385 PF11865.3 KLO18336.1 - 1.7e-43 148.3 0.8 1.2e-41 142.2 0.2 4.2 4 1 0 4 4 4 1 Domain of unknown function (DUF3385) Rapamycin_bind PF08771.6 KLO18336.1 - 3.4e-38 129.7 1.0 3.4e-38 129.7 0.7 3.5 5 0 0 5 5 1 1 Rapamycin binding domain HEAT_2 PF13646.1 KLO18336.1 - 1.4e-19 70.1 16.0 0.00055 20.1 0.1 10.6 7 2 4 11 11 11 6 HEAT repeats FATC PF02260.15 KLO18336.1 - 1.9e-15 56.0 0.3 6.9e-15 54.1 0.2 2.1 1 0 0 1 1 1 1 FATC domain HEAT PF02985.17 KLO18336.1 - 6.6e-11 41.3 6.6 3.3 8.0 0.0 11.7 14 0 0 14 14 10 1 HEAT repeat HEAT_EZ PF13513.1 KLO18336.1 - 8e-09 35.7 8.0 0.02 15.3 0.0 10.1 10 2 1 11 11 9 2 HEAT-like repeat TPR_19 PF14559.1 KLO18336.1 - 2.6e-05 24.4 1.0 0.31 11.4 0.2 3.7 3 1 0 3 3 2 2 Tetratricopeptide repeat TPR_14 PF13428.1 KLO18336.1 - 0.00067 20.0 0.1 0.44 11.3 0.0 4.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.1 KLO18336.1 - 0.0021 18.6 2.9 1.3 9.7 0.0 4.4 4 0 0 4 4 4 1 Tetratricopeptide repeat Apc3 PF12895.2 KLO18336.1 - 0.0023 18.0 0.2 0.12 12.5 0.0 3.0 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 UME PF08064.8 KLO18336.1 - 0.0051 16.7 8.9 0.2 11.6 0.3 4.7 4 0 0 4 4 3 1 UME (NUC010) domain TPR_7 PF13176.1 KLO18336.1 - 0.0064 16.1 4.2 3.5 7.6 0.1 4.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.1 KLO18336.1 - 0.014 15.0 0.6 7.1 6.3 0.0 3.4 2 0 0 2 2 2 0 TPR repeat RIX1 PF08167.7 KLO18336.1 - 0.031 13.9 6.9 0.05 13.2 0.0 4.5 4 1 0 4 4 4 0 rRNA processing/ribosome biogenesis TPR_2 PF07719.12 KLO18336.1 - 0.066 13.1 5.2 0.48 10.4 0.1 3.7 3 0 0 3 3 2 0 Tetratricopeptide repeat TPR_1 PF00515.23 KLO18336.1 - 0.095 12.3 0.3 0.79 9.4 0.1 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.1 KLO18336.1 - 0.29 11.6 2.9 1.2 9.7 0.1 3.5 2 0 0 2 2 2 0 Tetratricopeptide repeat CHD5 PF04420.9 KLO18337.1 - 1.6e-46 157.9 0.2 1.9e-46 157.6 0.1 1.1 1 0 0 1 1 1 1 CHD5-like protein Malate_synthase PF01274.17 KLO18338.1 - 3.5e-194 645.6 0.0 4.3e-194 645.3 0.0 1.0 1 0 0 1 1 1 1 Malate synthase OsmC PF02566.14 KLO18339.1 - 2.4e-14 53.3 0.0 3.4e-14 52.8 0.0 1.2 1 0 0 1 1 1 1 OsmC-like protein Zn_clus PF00172.13 KLO18341.1 - 0.006 16.4 10.5 0.011 15.6 7.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TF_Otx PF03529.8 KLO18341.1 - 0.75 10.0 6.9 1.5 9.1 4.8 1.5 1 0 0 1 1 1 0 Otx1 transcription factor Toxin_20 PF08089.6 KLO18341.1 - 3.2 7.7 6.8 4 7.4 4.1 1.5 1 1 0 1 1 1 0 Huwentoxin-II family FAT PF02259.18 KLO18342.1 - 3.9e-98 328.6 9.1 3.9e-98 328.6 6.3 1.9 2 0 0 2 2 2 1 FAT domain PI3_PI4_kinase PF00454.22 KLO18342.1 - 8.8e-54 182.4 0.0 2.4e-53 181.0 0.0 1.8 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase DUF3385 PF11865.3 KLO18342.1 - 1.3e-36 125.9 6.7 2.9e-36 124.8 0.2 4.5 4 2 2 6 6 6 1 Domain of unknown function (DUF3385) Rapamycin_bind PF08771.6 KLO18342.1 - 6.4e-25 87.1 0.2 2.9e-24 85.0 0.1 2.3 1 0 0 1 1 1 1 Rapamycin binding domain HEAT_2 PF13646.1 KLO18342.1 - 3e-17 62.6 6.7 2.7e-05 24.3 0.0 9.4 9 2 5 14 14 13 3 HEAT repeats FATC PF02260.15 KLO18342.1 - 3.5e-17 61.5 0.3 3.5e-17 61.5 0.2 2.0 2 0 0 2 2 2 1 FATC domain HEAT PF02985.17 KLO18342.1 - 1e-11 43.8 7.8 0.081 13.0 0.1 8.6 9 0 0 9 9 8 4 HEAT repeat Cnd1 PF12717.2 KLO18342.1 - 2.1e-07 30.9 5.6 0.017 14.9 0.0 5.7 5 1 2 7 7 7 2 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.1 KLO18342.1 - 1.6e-06 28.4 16.6 0.08 13.4 0.2 9.9 10 3 2 13 13 12 1 HEAT-like repeat UME PF08064.8 KLO18342.1 - 0.0027 17.6 0.0 0.0027 17.6 0.0 4.1 4 0 0 4 4 4 1 UME (NUC010) domain TPR_19 PF14559.1 KLO18342.1 - 0.0045 17.2 0.0 0.98 9.8 0.0 3.0 2 0 0 2 2 2 1 Tetratricopeptide repeat Cohesin_HEAT PF12765.2 KLO18342.1 - 0.068 13.1 3.4 8.6 6.4 0.0 4.0 4 0 0 4 4 4 0 HEAT repeat associated with sister chromatid cohesion Fungal_trans PF04082.13 KLO18343.1 - 1.7e-08 33.6 0.1 3.2e-08 32.7 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KLO18343.1 - 1.1e-07 31.5 11.4 1.9e-07 30.8 7.9 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain W2 PF02020.13 KLO18344.1 - 2.4e-17 62.6 1.1 2.4e-17 62.6 0.8 2.3 3 0 0 3 3 3 1 eIF4-gamma/eIF5/eIF2-epsilon HD_3 PF13023.1 KLO18344.1 - 0.02 14.6 0.1 0.038 13.7 0.1 1.4 1 0 0 1 1 1 0 HD domain DUF666 PF05006.7 KLO18344.1 - 0.035 14.1 0.1 0.068 13.1 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF666) NAAA-beta PF15508.1 KLO18344.1 - 0.09 13.1 0.0 0.48 10.8 0.0 2.2 1 0 0 1 1 1 0 beta subunit of N-acylethanolamine-hydrolyzing acid amidase Aldo_ket_red PF00248.16 KLO18345.1 - 2.4e-49 167.6 0.0 2.4e-33 115.1 0.0 2.6 2 1 1 3 3 3 2 Aldo/keto reductase family Mnd1 PF03962.10 KLO18345.1 - 7.6e-47 159.4 0.1 1.2e-46 158.7 0.1 1.2 1 0 0 1 1 1 1 Mnd1 family IncA PF04156.9 KLO18345.1 - 0.031 13.8 1.1 0.051 13.1 0.7 1.3 1 0 0 1 1 1 0 IncA protein GAS PF13851.1 KLO18345.1 - 0.11 11.7 2.7 0.2 10.8 1.9 1.4 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding Glyco_hydro_28 PF00295.12 KLO18346.1 - 2.7e-56 190.9 20.1 3.2e-56 190.6 13.9 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 Beta_helix PF13229.1 KLO18346.1 - 0.00023 20.9 31.0 0.00023 20.9 21.5 3.3 1 1 2 3 3 3 2 Right handed beta helix region Rap1-DNA-bind PF09197.5 KLO18347.1 - 9.4e-05 22.9 5.9 0.11 13.1 0.7 3.4 2 1 1 3 3 3 3 Rap1, DNA-binding BRCT PF00533.21 KLO18347.1 - 0.00048 20.2 0.0 0.00091 19.3 0.0 1.4 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain PIF1 PF05970.9 KLO18351.1 - 7.4e-14 51.4 0.0 7.9e-14 51.3 0.0 1.0 1 0 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.1 KLO18351.1 - 4.8e-07 29.5 0.0 5.7e-07 29.3 0.0 1.1 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 KLO18351.1 - 0.042 13.8 0.0 0.044 13.7 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain NB-ARC PF00931.17 KLO18351.1 - 0.056 12.3 0.0 0.075 11.8 0.0 1.1 1 0 0 1 1 1 0 NB-ARC domain AAA_22 PF13401.1 KLO18351.1 - 0.072 13.2 0.1 0.13 12.4 0.0 1.6 1 1 0 1 1 1 0 AAA domain Mg_chelatase PF01078.16 KLO18351.1 - 0.096 11.8 0.0 0.11 11.6 0.0 1.1 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI CbiA PF01656.18 KLO18351.1 - 0.13 11.6 0.0 0.14 11.5 0.0 1.1 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain UvrD_C_2 PF13538.1 KLO18352.1 - 0.0012 18.9 0.0 0.0019 18.2 0.0 1.3 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain RhoGEF PF00621.15 KLO18354.1 - 7.2e-37 127.0 0.3 1.6e-36 125.8 0.2 1.6 1 0 0 1 1 1 1 RhoGEF domain PH_10 PF15411.1 KLO18354.1 - 8.5e-35 119.4 0.0 2.2e-34 118.1 0.0 1.7 1 0 0 1 1 1 1 Pleckstrin homology domain CDC24 PF06395.6 KLO18354.1 - 2.5e-15 56.3 0.2 4.7e-15 55.4 0.1 1.5 1 0 0 1 1 1 1 CDC24 Calponin PB1 PF00564.19 KLO18354.1 - 2.9e-15 55.6 0.0 5.8e-15 54.7 0.0 1.5 1 0 0 1 1 1 1 PB1 domain PhyH PF05721.8 KLO18355.1 - 5.5e-46 157.2 0.0 6.7e-46 156.9 0.0 1.1 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) HK PF02110.10 KLO18356.1 - 4.9e-74 248.5 4.3 1.2e-72 244.0 3.0 2.2 1 1 0 1 1 1 1 Hydroxyethylthiazole kinase family TMP-TENI PF02581.12 KLO18356.1 - 1.8e-55 186.8 1.2 9e-55 184.5 0.1 2.6 3 0 0 3 3 3 1 Thiamine monophosphate synthase/TENI Carb_kinase PF01256.12 KLO18356.1 - 0.037 13.3 2.0 1.9 7.7 0.1 2.5 2 1 0 2 2 2 0 Carbohydrate kinase DUF2638 PF10937.3 KLO18358.1 - 0.09 13.8 0.3 1.1 10.2 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2638) WD40 PF00400.27 KLO18359.1 - 7.7e-20 69.9 16.0 3.8e-12 45.5 0.3 6.7 7 0 0 7 7 7 4 WD domain, G-beta repeat DUF3639 PF12341.3 KLO18359.1 - 5.3e-05 23.1 8.3 9e-05 22.3 0.0 3.8 4 0 0 4 4 4 1 Protein of unknown function (DUF3639) RrnaAD PF00398.15 KLO18360.1 - 7e-22 77.6 0.0 1e-21 77.1 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase DUF726 PF05277.7 KLO18362.1 - 1.4e-81 274.0 2.3 1.7e-81 273.7 1.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF726) Abhydrolase_6 PF12697.2 KLO18362.1 - 0.02 14.8 6.5 0.011 15.5 2.4 2.2 1 1 2 3 3 3 0 Alpha/beta hydrolase family Cutinase PF01083.17 KLO18362.1 - 0.035 13.8 0.0 0.063 13.0 0.0 1.3 1 0 0 1 1 1 0 Cutinase DUF747 PF05346.6 KLO18363.1 - 8.6e-107 357.0 3.9 1.1e-106 356.6 2.7 1.1 1 0 0 1 1 1 1 Eukaryotic membrane protein family KIF1B PF12423.3 KLO18364.1 - 0.13 12.3 0.5 0.33 11.0 0.4 1.7 1 0 0 1 1 1 0 Kinesin protein 1B CPSF73-100_C PF11718.3 KLO18365.1 - 3.3e-56 190.0 0.0 5e-56 189.4 0.0 1.2 1 0 0 1 1 1 1 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term Beta-Casp PF10996.3 KLO18365.1 - 7.2e-34 116.4 0.0 1.5e-33 115.4 0.0 1.6 1 0 0 1 1 1 1 Beta-Casp domain Lactamase_B PF00753.22 KLO18365.1 - 6.7e-13 48.7 0.4 2.1e-12 47.1 0.3 1.7 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily RMMBL PF07521.7 KLO18365.1 - 1.7e-11 43.7 0.5 3.6e-11 42.6 0.4 1.6 1 0 0 1 1 1 1 RNA-metabolising metallo-beta-lactamase Lactamase_B_2 PF12706.2 KLO18365.1 - 6.9e-09 35.5 1.4 2e-08 34.0 0.4 2.1 2 0 0 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 KLO18365.1 - 1.4e-05 24.8 0.0 6.6e-05 22.6 0.0 2.2 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Glyco_hydro_61 PF03443.9 KLO18366.1 - 2.4e-45 155.0 0.0 3e-45 154.7 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 ADH_zinc_N PF00107.21 KLO18367.1 - 4.6e-23 81.1 0.8 7.7e-23 80.4 0.6 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 KLO18367.1 - 1.8e-05 25.6 0.0 3.8e-05 24.5 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase CRC_subunit PF08624.5 KLO18369.1 - 6.8e-40 136.1 0.0 1e-39 135.6 0.0 1.2 1 0 0 1 1 1 1 Chromatin remodelling complex Rsc7/Swp82 subunit TatD_DNase PF01026.16 KLO18370.1 - 2.8e-41 141.4 0.0 3.5e-41 141.0 0.0 1.1 1 0 0 1 1 1 1 TatD related DNase Sec7 PF01369.15 KLO18371.1 - 1.2e-36 126.1 0.0 2.6e-36 125.0 0.0 1.5 1 0 0 1 1 1 1 Sec7 domain PH_9 PF15410.1 KLO18371.1 - 3.1e-28 98.2 0.0 5.6e-28 97.4 0.0 1.4 1 0 0 1 1 1 1 Pleckstrin homology domain PH PF00169.24 KLO18371.1 - 0.008 16.3 0.0 0.028 14.6 0.0 1.9 1 0 0 1 1 1 1 PH domain Lzipper-MIP1 PF14389.1 KLO18371.1 - 0.35 10.9 3.5 0.53 10.4 1.5 1.9 2 0 0 2 2 2 0 Leucine-zipper of ternary complex factor MIP1 GATA PF00320.22 KLO18372.1 - 1.3e-18 66.0 2.9 2.4e-18 65.1 2.0 1.5 1 0 0 1 1 1 1 GATA zinc finger Git3 PF11710.3 KLO18373.1 - 2.9e-05 23.7 6.6 5.5e-05 22.8 4.6 1.4 1 0 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 7tm_1 PF00001.16 KLO18373.1 - 0.00095 18.3 2.0 0.0013 17.9 1.4 1.5 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Peptidase_A22B PF04258.8 KLO18374.1 - 7.6e-65 219.2 10.5 9.1e-65 219.0 7.3 1.0 1 0 0 1 1 1 1 Signal peptide peptidase Dynamitin PF04912.9 KLO18375.1 - 3e-19 69.0 3.7 1.8e-18 66.5 0.1 3.1 2 2 0 2 2 2 1 Dynamitin Pheromone PF08015.6 KLO18375.1 - 0.29 11.9 0.0 0.29 11.9 0.0 3.7 3 2 0 4 4 4 0 Fungal mating-type pheromone Baculo_PEP_C PF04513.7 KLO18375.1 - 0.5 10.1 4.6 15 5.4 0.1 3.3 2 1 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Tropomyosin_1 PF12718.2 KLO18375.1 - 1.6 8.6 6.6 5.3 6.8 0.0 3.9 3 1 1 4 4 4 0 Tropomyosin like Asparaginase_2 PF01112.13 KLO18376.1 - 1e-56 192.0 0.0 2.2e-41 141.6 0.0 2.4 2 1 0 2 2 2 2 Asparaginase G_glu_transpept PF01019.16 KLO18376.1 - 0.00074 18.1 0.2 0.056 11.9 0.2 2.1 2 0 0 2 2 2 2 Gamma-glutamyltranspeptidase Mannosyl_trans2 PF04188.8 KLO18377.1 - 1.7e-66 225.0 25.2 2.1e-66 224.7 17.5 1.0 1 0 0 1 1 1 1 Mannosyltransferase (PIG-V)) XPG_I PF00867.13 KLO18378.1 - 2.1e-20 72.5 0.0 5.6e-20 71.2 0.0 1.8 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.12 KLO18378.1 - 1.9e-06 28.0 0.0 6.7e-06 26.2 0.0 1.9 1 1 0 1 1 1 1 XPG N-terminal domain XPG_I_2 PF12813.2 KLO18378.1 - 0.074 12.5 0.0 0.13 11.6 0.0 1.4 1 0 0 1 1 1 0 XPG domain containing Pex24p PF06398.6 KLO18379.1 - 1.8e-23 82.9 12.6 1.8e-23 82.9 8.8 3.0 2 1 0 2 2 2 1 Integral peroxisomal membrane peroxin FA PF08736.6 KLO18379.1 - 4.1 7.2 7.9 10 6.0 4.2 2.2 2 0 0 2 2 2 0 FERM adjacent (FA) DUF2419 PF10343.4 KLO18380.1 - 1.8e-10 40.5 0.0 1.6e-08 34.1 0.0 2.4 2 1 0 2 2 2 2 Protein of unknown function (DUF2419) YqeY PF09424.5 KLO18381.1 - 1.9e-26 92.6 1.2 2.5e-26 92.2 0.8 1.2 1 0 0 1 1 1 1 Yqey-like protein SATase_N PF06426.9 KLO18381.1 - 0.32 11.2 3.1 1.4 9.2 0.8 2.6 2 2 0 2 2 2 0 Serine acetyltransferase, N-terminal zf-rbx1 PF12678.2 KLO18382.1 - 6e-13 48.7 0.7 1.2e-12 47.7 0.5 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_2 PF13639.1 KLO18382.1 - 1.2e-11 44.1 7.2 3e-11 42.9 2.4 2.3 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4 PF00097.20 KLO18382.1 - 3.1e-08 33.1 1.2 7.6e-08 31.8 0.8 1.7 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KLO18382.1 - 2.3e-06 27.1 4.3 4.9e-05 22.9 0.8 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KLO18382.1 - 3.5e-06 26.9 1.8 3.5e-06 26.9 1.3 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KLO18382.1 - 0.0003 20.4 5.0 0.0021 17.7 3.6 2.1 1 1 1 2 2 2 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 KLO18382.1 - 0.00031 20.4 4.7 0.0011 18.6 2.9 2.2 1 1 0 1 1 1 1 RING-type zinc-finger zf-Apc11 PF12861.2 KLO18382.1 - 0.00059 19.6 1.4 0.0014 18.4 0.4 1.9 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_4 PF15227.1 KLO18382.1 - 0.011 15.6 1.4 0.021 14.6 1.0 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING FANCL_C PF11793.3 KLO18382.1 - 0.15 12.0 0.2 0.37 10.7 0.1 1.6 1 0 0 1 1 1 0 FANCL C-terminal domain PAP1 PF08601.5 KLO18382.1 - 1.4 8.5 17.4 2.4 7.7 12.1 1.3 1 0 0 1 1 1 0 Transcription factor PAP1 zf-RING_4 PF14570.1 KLO18382.1 - 3.4 7.3 5.0 0.99 9.0 1.2 1.7 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain Amidohydro_3 PF07969.6 KLO18383.1 - 1.6e-74 251.5 0.2 1.9e-74 251.2 0.2 1.0 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_4 PF13147.1 KLO18383.1 - 6.2e-09 36.2 0.9 3.8e-05 23.8 0.0 2.5 2 1 0 2 2 2 2 Amidohydrolase Amidohydro_1 PF01979.15 KLO18383.1 - 4.5e-05 23.2 0.0 7.8e-05 22.4 0.0 1.7 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_5 PF13594.1 KLO18383.1 - 0.041 13.6 0.0 0.16 11.7 0.0 2.0 1 0 0 1 1 1 0 Amidohydrolase SNF2_N PF00176.18 KLO18384.1 - 3.4e-60 203.3 0.0 4.8e-60 202.8 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 KLO18384.1 - 3.1e-12 46.1 0.0 5.7e-12 45.3 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 KLO18384.1 - 3.4e-10 39.6 0.0 1.2e-09 37.9 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase ResIII PF04851.10 KLO18384.1 - 1.7e-06 27.9 0.3 7.6e-06 25.8 0.0 2.2 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.3 KLO18384.1 - 0.00012 21.0 0.2 0.00024 20.0 0.1 1.4 1 0 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 Na_H_Exchanger PF00999.16 KLO18385.1 - 2.9e-57 193.9 24.7 3.8e-57 193.5 17.1 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Na_H_Exchanger PF00999.16 KLO18386.1 - 1.9e-53 181.3 26.1 2.3e-53 181.0 18.1 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family EB PF01683.13 KLO18388.1 - 1.7 8.8 36.7 4.2 7.5 2.5 4.6 3 2 2 5 5 5 0 EB module hEGF PF12661.2 KLO18389.1 - 0.017 15.1 1.8 0.017 15.1 1.2 4.3 4 0 0 4 4 4 0 Human growth factor-like EGF NPP1 PF05630.6 KLO18389.1 - 0.081 12.6 0.4 0.16 11.6 0.1 1.5 1 1 0 1 1 1 0 Necrosis inducing protein (NPP1) hEGF PF12661.2 KLO18390.1 - 0.026 14.6 0.6 0.026 14.6 0.4 4.5 4 0 0 4 4 4 0 Human growth factor-like EGF EGF_2 PF07974.8 KLO18390.1 - 0.035 14.2 2.4 0.035 14.2 1.7 3.9 4 0 0 4 4 4 0 EGF-like domain DUF1279 PF06916.8 KLO18391.1 - 3.2e-17 62.5 0.3 5e-17 61.9 0.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1279) DUF2132 PF09905.4 KLO18391.1 - 0.17 11.9 0.0 0.31 11.0 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2132) RPEL PF02755.10 KLO18392.1 - 9.8e-17 59.7 4.2 1.2e-08 34.0 1.4 2.2 2 0 0 2 2 2 2 RPEL repeat DDE_Tnp_IS66 PF03050.9 KLO18392.1 - 0.038 13.2 0.9 0.041 13.1 0.6 1.1 1 0 0 1 1 1 0 Transposase IS66 family Microtub_bind PF13931.1 KLO18392.1 - 0.071 13.2 3.3 0.079 13.1 2.3 1.1 1 0 0 1 1 1 0 Kinesin-associated microtubule-binding MCPVI PF02993.9 KLO18392.1 - 2.9 7.9 8.6 0.38 10.8 3.1 1.6 1 1 1 2 2 2 0 Minor capsid protein VI DUF1814 PF08843.6 KLO18393.1 - 0.00011 22.1 0.0 0.00019 21.3 0.0 1.6 1 1 0 1 1 1 1 Nucleotidyl transferase of unknown function (DUF1814) Dioxygenase_C PF00775.16 KLO18394.1 - 9.6e-51 171.6 0.0 1.5e-50 171.0 0.0 1.2 1 0 0 1 1 1 1 Dioxygenase Dioxygenase_N PF04444.9 KLO18394.1 - 3.4e-15 55.7 0.0 5.6e-15 55.0 0.0 1.3 1 0 0 1 1 1 1 Catechol dioxygenase N terminus Rax2 PF12768.2 KLO18396.1 - 9e-80 267.8 30.2 2.2e-65 220.6 2.4 6.6 5 2 1 7 7 7 4 Cortical protein marker for cell polarity SH3_1 PF00018.23 KLO18396.1 - 1e-11 43.9 0.1 2.4e-11 42.8 0.1 1.7 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 KLO18396.1 - 1.5e-10 40.4 0.6 3.6e-10 39.2 0.1 1.9 2 0 0 2 2 2 1 Variant SH3 domain Reg_prop PF07494.6 KLO18396.1 - 0.0073 16.1 1.0 0.19 11.8 0.0 3.9 3 0 0 3 3 3 1 Two component regulator propeller DUF4083 PF13314.1 KLO18396.1 - 0.14 11.9 0.1 0.28 11.0 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4083) Tmemb_9 PF05434.6 KLO18396.1 - 0.39 10.4 0.0 0.67 9.6 0.0 1.3 1 0 0 1 1 1 0 TMEM9 zf-C2H2_2 PF12756.2 KLO18397.1 - 2.6e-36 123.7 9.8 1.6e-30 105.1 0.2 3.3 2 1 0 3 3 3 3 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.3 KLO18397.1 - 1.2e-11 44.3 11.4 1.1e-08 35.0 1.5 3.7 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 KLO18397.1 - 2.9e-07 30.4 2.6 2.9e-07 30.4 1.8 2.5 3 0 0 3 3 3 1 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.1 KLO18397.1 - 0.0082 16.0 4.8 0.11 12.4 0.4 3.3 3 0 0 3 3 3 1 C2H2-type zinc finger zf-C2H2_4 PF13894.1 KLO18397.1 - 0.014 15.7 12.9 1.3 9.5 0.7 4.0 4 0 0 4 4 4 0 C2H2-type zinc finger DUF1075 PF06388.6 KLO18397.1 - 0.027 14.1 0.1 0.057 13.0 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1075) zf-DBF PF07535.7 KLO18397.1 - 0.033 13.8 0.3 0.033 13.8 0.2 3.5 4 0 0 4 4 4 0 DBF zinc finger DUF3505 PF12013.3 KLO18397.1 - 0.49 10.6 5.1 1.4 9.2 0.1 3.1 3 1 1 4 4 4 0 Protein of unknown function (DUF3505) Vps53_N PF04100.7 KLO18398.1 - 5e-85 285.5 1.7 5e-85 285.5 1.2 1.7 2 0 0 2 2 2 1 Vps53-like, N-terminal DUF2450 PF10475.4 KLO18398.1 - 0.00016 20.6 7.1 0.00033 19.6 4.9 1.4 1 0 0 1 1 1 1 Protein of unknown function N-terminal domain (DUF2450) Spc7 PF08317.6 KLO18398.1 - 0.0042 15.7 9.6 0.0085 14.7 6.7 1.4 1 0 0 1 1 1 1 Spc7 kinetochore protein DUF812 PF05667.6 KLO18398.1 - 0.0045 15.5 6.1 0.0084 14.6 4.2 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF812) Sec5 PF15469.1 KLO18398.1 - 0.0068 16.1 4.7 0.022 14.5 3.2 1.8 1 0 0 1 1 1 1 Exocyst complex component Sec5 Atg14 PF10186.4 KLO18398.1 - 0.055 12.4 3.9 0.1 11.5 2.7 1.5 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 T2SF PF00482.18 KLO18398.1 - 0.15 11.9 2.8 0.72 9.7 1.8 2.3 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein F CorA PF01544.13 KLO18398.1 - 0.56 9.1 9.6 0.43 9.5 5.1 1.9 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein DUF948 PF06103.6 KLO18398.1 - 0.62 9.9 7.6 9.6 6.1 1.4 3.8 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) COG2 PF06148.6 KLO18398.1 - 1 9.2 13.9 4.2 7.2 2.4 3.7 2 2 1 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 Baculo_PEP_C PF04513.7 KLO18398.1 - 1 9.1 10.7 1.3 8.8 5.3 2.8 3 1 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus CDC37_N PF03234.9 KLO18398.1 - 6.3 7.0 13.5 5.3 7.3 6.7 2.6 2 1 0 2 2 2 0 Cdc37 N terminal kinase binding IncA PF04156.9 KLO18398.1 - 6.7 6.2 15.8 3.3 7.2 8.3 2.4 2 0 0 2 2 2 0 IncA protein VSP PF03302.8 KLO18399.1 - 0.084 11.4 0.1 0.084 11.4 0.0 1.5 2 0 0 2 2 2 0 Giardia variant-specific surface protein MtrF PF09472.5 KLO18399.1 - 0.33 10.2 1.4 0.62 9.3 1.0 1.4 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, F subunit (MtrF) AAA_5 PF07728.9 KLO18401.1 - 0.0011 18.6 0.1 0.016 14.8 0.0 2.2 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) Rpr2 PF04032.11 KLO18402.1 - 7.5e-19 67.3 6.5 2.4e-18 65.7 4.5 1.8 1 1 0 1 1 1 1 RNAse P Rpr2/Rpp21/SNM1 subunit domain Ribosomal_S5 PF00333.15 KLO18403.1 - 9.7e-28 95.7 3.7 1.2e-27 95.3 1.1 2.2 2 0 0 2 2 2 1 Ribosomal protein S5, N-terminal domain Ribosomal_S5_C PF03719.10 KLO18403.1 - 1.1e-22 79.0 0.1 1.9e-22 78.3 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain Abhydrolase_3 PF07859.8 KLO18404.1 - 2.7e-16 59.7 0.0 1.9e-15 57.0 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.23 KLO18404.1 - 5.5e-10 38.5 0.0 1.5e-09 37.0 0.0 1.6 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_5 PF12695.2 KLO18404.1 - 3.2e-06 26.9 0.0 3.8e-06 26.7 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KLO18404.1 - 4.7e-06 26.6 0.1 3.3e-05 23.8 0.1 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF2424 PF10340.4 KLO18404.1 - 1.5e-05 23.7 0.0 2.1e-05 23.3 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2424) Peptidase_S9 PF00326.16 KLO18404.1 - 7.8e-05 21.9 0.0 0.0091 15.2 0.0 2.6 3 0 0 3 3 3 1 Prolyl oligopeptidase family DUF3089 PF11288.3 KLO18404.1 - 0.066 12.3 0.0 0.11 11.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3089) Lipase_3 PF01764.20 KLO18404.1 - 0.12 11.9 0.0 0.22 11.1 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) ubiquitin PF00240.18 KLO18405.1 - 4.3e-14 51.6 0.7 9e-13 47.4 0.1 2.3 2 0 0 2 2 2 1 Ubiquitin family Rad60-SLD PF11976.3 KLO18405.1 - 8.9e-06 25.3 0.8 1.4e-05 24.6 0.2 1.6 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 KLO18405.1 - 0.022 15.0 0.1 0.053 13.7 0.0 1.8 1 1 0 1 1 1 0 Ubiquitin-like domain Peptidase_C3 PF00548.15 KLO18405.1 - 0.044 13.5 0.5 0.073 12.8 0.3 1.3 1 1 0 1 1 1 0 3C cysteine protease (picornain 3C) Spore_III_AF PF09581.5 KLO18405.1 - 0.21 11.4 4.0 0.31 10.8 2.8 1.3 1 0 0 1 1 1 0 Stage III sporulation protein AF (Spore_III_AF) Pox_RNA_Pol_19 PF05320.7 KLO18405.1 - 0.27 10.9 3.8 0.36 10.5 2.6 1.2 1 0 0 1 1 1 0 Poxvirus DNA-directed RNA polymerase 19 kDa subunit Hid1 PF12722.2 KLO18405.1 - 0.3 8.7 3.1 0.29 8.7 2.2 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein NPR3 PF03666.8 KLO18405.1 - 0.38 9.2 5.3 0.49 8.8 3.7 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 ODC_AZ PF02100.12 KLO18406.1 - 4.9e-19 67.8 0.0 7.3e-19 67.2 0.0 1.2 1 0 0 1 1 1 1 Ornithine decarboxylase antizyme DUF1771 PF08590.5 KLO18407.1 - 1.3e-18 66.7 3.7 1.3e-18 66.7 2.6 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF1771) Smr PF01713.16 KLO18407.1 - 3.1e-15 56.1 0.1 7.8e-15 54.8 0.1 1.7 1 0 0 1 1 1 1 Smr domain PAT1 PF09770.4 KLO18407.1 - 0.26 9.4 11.5 0.32 9.1 8.0 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DnaJ PF00226.26 KLO18408.1 - 1.4e-09 37.5 0.1 2.4e-09 36.8 0.1 1.4 1 0 0 1 1 1 1 DnaJ domain Remorin_C PF03763.8 KLO18409.1 - 1.2 8.6 15.4 0.25 10.8 8.2 1.7 2 0 0 2 2 2 0 Remorin, C-terminal region Amidohydro_2 PF04909.9 KLO18410.1 - 0.00099 18.7 0.0 0.0017 18.0 0.0 1.4 1 0 0 1 1 1 1 Amidohydrolase PAD_N PF08526.5 KLO18410.1 - 0.0098 15.9 0.1 0.017 15.1 0.1 1.4 1 0 0 1 1 1 1 Protein-arginine deiminase (PAD) N-terminal domain Cir_N PF10197.4 KLO18411.1 - 0.0025 17.8 0.1 0.0025 17.8 0.1 3.7 3 0 0 3 3 3 1 N-terminal domain of CBF1 interacting co-repressor CIR Lip_prot_lig_C PF10437.4 KLO18412.1 - 0.0015 18.1 0.0 0.053 13.2 0.0 2.3 2 0 0 2 2 2 1 Bacterial lipoate protein ligase C-terminus Med25 PF11232.3 KLO18412.1 - 0.0073 15.9 0.2 0.016 14.8 0.1 1.5 1 0 0 1 1 1 1 Mediator complex subunit 25 PTOV activation and synapsin 2 Lactamase_B PF00753.22 KLO18414.1 - 4.6e-12 45.9 0.1 1.1e-11 44.8 0.0 1.7 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 KLO18414.1 - 6.7e-06 25.7 0.0 9.8e-06 25.2 0.0 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain E1-E2_ATPase PF00122.15 KLO18416.1 - 2.1e-28 98.9 0.1 5.6e-28 97.5 0.1 1.7 1 0 0 1 1 1 1 E1-E2 ATPase HAD PF12710.2 KLO18416.1 - 1.5e-24 87.2 0.0 2.5e-24 86.5 0.0 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 KLO18416.1 - 1.2e-22 81.4 0.0 8.6e-17 62.2 0.0 3.1 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase P5-ATPase PF12409.3 KLO18416.1 - 1.6e-15 57.0 0.5 3.7e-15 55.8 0.3 1.6 1 0 0 1 1 1 1 P5-type ATPase cation transporter Cation_ATPase_C PF00689.16 KLO18416.1 - 4.6e-07 29.5 6.2 1.8e-06 27.6 4.3 2.0 1 0 0 1 1 1 1 Cation transporting ATPase, C-terminus Hydrolase_like2 PF13246.1 KLO18416.1 - 5.9e-06 26.1 0.0 1.7e-05 24.7 0.0 1.7 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Cation_ATPase_N PF00690.21 KLO18416.1 - 0.0035 16.7 0.0 0.0087 15.4 0.0 1.7 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 KLO18416.1 - 0.11 12.0 0.0 0.18 11.3 0.0 1.3 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase V-SNARE_C PF12352.3 KLO18417.1 - 4.4e-16 58.7 1.5 5.8e-16 58.3 0.3 1.8 2 0 0 2 2 2 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.8 KLO18417.1 - 1.1e-07 31.3 0.3 3.4e-07 29.8 0.0 1.9 2 1 0 2 2 2 1 Sec20 Transposase_22 PF02994.9 KLO18417.1 - 0.021 13.3 0.1 0.026 13.0 0.1 1.1 1 0 0 1 1 1 0 L1 transposable element Plasmid_RAQPRD PF09686.5 KLO18417.1 - 0.046 13.8 1.3 0.38 10.8 0.7 2.4 2 0 0 2 2 2 0 Plasmid protein of unknown function (Plasmid_RAQPRD) TPR_MLP1_2 PF07926.7 KLO18417.1 - 0.088 12.5 2.2 0.15 11.8 1.5 1.7 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein Wbp11 PF09429.5 KLO18417.1 - 0.1 12.6 3.5 5.8 6.9 0.0 2.4 2 0 0 2 2 2 0 WW domain binding protein 11 FAM72 PF14976.1 KLO18418.1 - 4.2e-17 62.3 2.3 5e-07 29.6 0.0 3.2 3 0 0 3 3 3 3 FAM72 protein Yippee-Mis18 PF03226.9 KLO18418.1 - 0.016 15.2 5.0 0.2 11.7 3.7 2.1 1 1 1 2 2 2 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly Nop25 PF09805.4 KLO18419.1 - 4.7e-14 52.6 22.3 4.7e-14 52.6 15.5 3.0 2 2 0 2 2 2 1 Nucleolar protein 12 (25kDa) Creatinase_N PF01321.13 KLO18419.1 - 0.036 14.5 0.0 0.1 13.1 0.0 1.9 1 1 0 1 1 1 0 Creatinase/Prolidase N-terminal domain MIF4G PF02854.14 KLO18421.1 - 2.1e-50 171.0 0.2 4.3e-27 94.9 0.0 4.0 4 0 0 4 4 4 3 MIF4G domain Upf2 PF04050.9 KLO18421.1 - 5.5e-24 84.8 14.1 5.5e-24 84.8 9.7 3.6 3 0 0 3 3 3 2 Up-frameshift suppressor 2 DUF342 PF03961.8 KLO18422.1 - 0.065 11.6 3.3 0.1 10.9 2.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF342) DUF4407 PF14362.1 KLO18422.1 - 0.99 8.2 15.2 1.9 7.3 10.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF3584 PF12128.3 KLO18422.1 - 3.6 4.8 17.8 5.6 4.1 12.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Macoilin PF09726.4 KLO18422.1 - 4.8 5.3 18.8 8 4.6 13.0 1.2 1 0 0 1 1 1 0 Transmembrane protein Glyco_transf_49 PF13896.1 KLO18423.1 - 0.0011 18.2 0.0 0.0011 18.2 0.0 1.7 2 0 0 2 2 2 1 Glycosyl-transferase for dystroglycan DUF72 PF01904.13 KLO18423.1 - 0.0095 15.7 3.0 0.04 13.6 2.1 1.8 1 1 0 1 1 1 1 Protein of unknown function DUF72 DUF805 PF05656.9 KLO18423.1 - 0.04 13.7 0.1 0.082 12.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF805) p450 PF00067.17 KLO18424.1 - 8.4e-61 205.8 0.1 2.6e-60 204.2 0.0 1.7 1 1 0 1 1 1 1 Cytochrome P450 Fe-ADH PF00465.14 KLO18425.1 - 1.1e-77 261.1 0.6 1.3e-77 260.9 0.4 1.0 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.1 KLO18425.1 - 7.4e-16 58.2 0.0 9.7e-16 57.8 0.0 1.1 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Peripla_BP_4 PF13407.1 KLO18425.1 - 0.046 13.0 0.0 0.097 12.0 0.0 1.5 1 0 0 1 1 1 0 Periplasmic binding protein domain DUF1967 PF09269.6 KLO18425.1 - 0.21 11.2 0.1 0.21 11.2 0.1 2.1 3 0 0 3 3 3 0 Domain of unknown function (DUF1967) ADH_zinc_N PF00107.21 KLO18426.1 - 2.8e-34 117.4 0.2 4e-34 116.9 0.1 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 KLO18426.1 - 3.5e-13 50.5 0.0 9.7e-13 49.1 0.0 1.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KLO18426.1 - 1.4e-08 34.4 0.0 8.8e-08 31.8 0.0 2.2 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain NAD_binding_10 PF13460.1 KLO18426.1 - 0.0021 18.0 0.4 0.0037 17.2 0.3 1.4 1 0 0 1 1 1 1 NADH(P)-binding AlaDh_PNT_C PF01262.16 KLO18426.1 - 0.071 12.6 0.2 0.13 11.8 0.2 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain RabGAP-TBC PF00566.13 KLO18427.1 - 1.1e-53 181.8 0.7 1.1e-53 181.8 0.5 1.5 2 0 0 2 2 2 1 Rab-GTPase-TBC domain DUF641 PF04859.7 KLO18427.1 - 0.0059 16.3 0.4 0.012 15.3 0.3 1.5 1 0 0 1 1 1 1 Plant protein of unknown function (DUF641) TMF_DNA_bd PF12329.3 KLO18427.1 - 0.077 12.8 0.4 0.22 11.3 0.3 1.7 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding NACHT PF05729.7 KLO18429.1 - 2.5e-07 30.5 0.0 6.2e-07 29.2 0.0 1.7 1 1 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 KLO18429.1 - 0.00042 20.3 0.0 0.0072 16.3 0.0 2.5 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 KLO18429.1 - 0.0031 17.6 0.0 0.01 16.0 0.0 1.9 1 0 0 1 1 1 1 AAA domain APS_kinase PF01583.15 KLO18429.1 - 0.0037 16.9 0.1 0.0074 15.9 0.0 1.5 1 0 0 1 1 1 1 Adenylylsulphate kinase ABC_tran PF00005.22 KLO18429.1 - 0.0079 16.4 0.0 0.14 12.4 0.0 2.4 2 0 0 2 2 2 1 ABC transporter AAA_18 PF13238.1 KLO18429.1 - 0.02 15.1 0.2 0.074 13.3 0.1 2.1 2 1 0 2 2 2 0 AAA domain AAA_17 PF13207.1 KLO18429.1 - 0.027 15.3 0.0 0.098 13.4 0.0 2.1 2 0 0 2 2 2 0 AAA domain Torsin PF06309.6 KLO18429.1 - 0.038 13.8 0.0 0.13 12.1 0.0 1.8 1 0 0 1 1 1 0 Torsin AAA_19 PF13245.1 KLO18429.1 - 0.068 12.9 0.0 0.6 9.8 0.0 2.4 2 0 0 2 2 2 0 Part of AAA domain NB-ARC PF00931.17 KLO18429.1 - 0.12 11.2 0.0 0.22 10.3 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain Rad17 PF03215.10 KLO18429.1 - 0.19 10.3 0.1 0.31 9.6 0.0 1.2 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein RRM_2 PF04059.7 KLO18431.1 - 6.3e-31 106.2 0.4 8e-31 105.9 0.3 1.1 1 0 0 1 1 1 1 RNA recognition motif 2 RRM_6 PF14259.1 KLO18431.1 - 0.0021 18.0 0.0 0.0038 17.1 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 KLO18431.1 - 0.0072 15.9 0.0 0.014 15.0 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) STE3 PF02076.10 KLO18433.1 - 1.1e-51 175.5 12.1 1.4e-51 175.3 8.4 1.1 1 0 0 1 1 1 1 Pheromone A receptor GidB PF02527.10 KLO18433.1 - 0.002 17.2 0.0 0.0029 16.7 0.0 1.2 1 0 0 1 1 1 1 rRNA small subunit methyltransferase G Aldo_ket_red PF00248.16 KLO18440.1 - 2.9e-62 210.0 0.0 3.3e-62 209.8 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Tet_JBP PF12851.2 KLO18442.1 - 7.4e-10 38.3 0.0 1.4e-09 37.5 0.0 1.3 1 0 0 1 1 1 1 Oxygenase domain of the 2OGFeDO superfamily DUF1556 PF07590.6 KLO18443.1 - 2.8 8.2 10.7 1.3 9.3 3.4 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1556) MULE PF10551.4 KLO18444.1 - 1.1e-07 31.8 0.0 3.8e-07 30.1 0.0 1.9 1 0 0 1 1 1 1 MULE transposase domain SWIM PF04434.12 KLO18444.1 - 0.016 14.6 1.0 0.038 13.4 0.7 1.6 1 0 0 1 1 1 0 SWIM zinc finger Cauli_VI PF01693.11 KLO18445.1 - 0.11 12.5 0.0 0.21 11.6 0.0 1.4 1 0 0 1 1 1 0 Caulimovirus viroplasmin Mito_fiss_reg PF05308.6 KLO18445.1 - 4.1 6.6 6.1 6.7 5.9 4.3 1.3 1 0 0 1 1 1 0 Mitochondrial fission regulator MULE PF10551.4 KLO18447.1 - 1.6e-11 44.2 0.0 2.7e-11 43.4 0.0 1.4 1 0 0 1 1 1 1 MULE transposase domain Mpv17_PMP22 PF04117.7 KLO18447.1 - 0.11 12.1 0.0 0.27 10.8 0.0 1.6 1 0 0 1 1 1 0 Mpv17 / PMP22 family TSKS PF15358.1 KLO18450.1 - 0.15 10.2 0.0 0.16 10.0 0.0 1.1 1 0 0 1 1 1 0 Testis-specific serine kinase substrate Utp12 PF04003.7 KLO18452.1 - 0.016 15.1 7.0 0.13 12.1 1.7 2.2 1 1 1 2 2 2 0 Dip2/Utp12 Family Baculo_PEP_C PF04513.7 KLO18452.1 - 0.041 13.7 5.0 0.053 13.3 3.5 1.2 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus CK2S PF15011.1 KLO18452.1 - 0.15 11.8 8.9 0.18 11.5 5.2 1.9 1 1 1 2 2 2 0 Casein Kinase 2 substrate Muted PF14942.1 KLO18452.1 - 3.3 7.5 10.2 2.2 8.1 5.0 1.9 1 1 1 2 2 2 0 Organelle biogenesis, Muted-like protein GTA_TIM PF13547.1 KLO18460.1 - 0.038 12.9 3.3 0.041 12.8 1.1 1.9 1 1 0 2 2 2 0 GTA TIM-barrel-like domain MscS_porin PF12795.2 KLO18463.1 - 0.14 11.4 1.4 0.18 11.0 1.0 1.2 1 0 0 1 1 1 0 Mechanosensitive ion channel porin domain Antimicrobial11 PF08106.6 KLO18467.1 - 0.39 10.5 3.4 0.9 9.4 0.5 2.5 2 0 0 2 2 2 0 Formaecin family COX5A PF02284.11 KLO18474.1 - 0.11 12.4 0.0 0.47 10.4 0.0 2.0 2 0 0 2 2 2 0 Cytochrome c oxidase subunit Va YrvL PF14184.1 KLO18476.1 - 0.0071 16.1 0.1 0.012 15.3 0.0 1.5 2 0 0 2 2 2 1 Regulatory protein YrvL CCDC144C PF14915.1 KLO18481.1 - 0.0047 15.8 0.1 0.005 15.8 0.1 1.2 1 0 0 1 1 1 1 CCDC144C protein coiled-coil region XkdW PF09636.5 KLO18481.1 - 0.023 14.5 0.5 0.027 14.3 0.3 1.2 1 0 0 1 1 1 0 XkdW protein FadA PF09403.5 KLO18481.1 - 0.038 13.9 0.4 0.057 13.4 0.3 1.3 1 1 0 1 1 1 0 Adhesion protein FadA HJURP_C PF12347.3 KLO18481.1 - 0.064 12.8 0.1 0.092 12.3 0.1 1.4 1 0 0 1 1 1 0 Holliday junction regulator protein family C-terminal repeat HDOD PF08668.7 KLO18481.1 - 0.081 12.1 0.0 0.093 11.9 0.0 1.1 1 0 0 1 1 1 0 HDOD domain IncA PF04156.9 KLO18481.1 - 0.13 11.8 0.2 0.13 11.8 0.1 1.1 1 0 0 1 1 1 0 IncA protein Vint PF14623.1 KLO18482.1 - 0.13 11.7 0.0 0.15 11.5 0.0 1.1 1 0 0 1 1 1 0 Hint-domain Zn_clus PF00172.13 KLO18484.1 - 7.4 6.5 14.6 14 5.7 10.1 1.4 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Sec2p PF06428.6 KLO18486.1 - 0.078 12.8 0.0 0.2 11.5 0.0 1.7 1 0 0 1 1 1 0 GDP/GTP exchange factor Sec2p DUF4407 PF14362.1 KLO18488.1 - 1.2 8.0 7.0 1 8.2 2.5 2.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4407) Aldo_ket_red PF00248.16 KLO18489.1 - 2.4e-65 220.2 0.0 2.7e-65 220.0 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family LRR_4 PF12799.2 KLO18490.1 - 0.023 14.3 1.8 36 4.1 1.0 4.1 2 1 1 3 3 3 0 Leucine Rich repeats (2 copies) PSD5 PF07637.6 KLO18492.1 - 0.11 12.5 0.6 2.6 8.1 0.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1595) FemAB PF02388.11 KLO18492.1 - 0.12 11.0 0.0 0.17 10.5 0.0 1.2 1 0 0 1 1 1 0 FemAB family F-box-like PF12937.2 KLO18493.1 - 0.0012 18.5 0.8 0.013 15.1 0.1 3.1 4 1 0 4 4 4 1 F-box-like F-box-like PF12937.2 KLO18494.1 - 0.00032 20.3 0.1 0.0011 18.6 0.1 2.0 1 0 0 1 1 1 1 F-box-like DUF3557 PF12078.3 KLO18494.1 - 0.00054 19.7 0.2 0.0079 15.9 0.0 2.6 2 0 0 2 2 2 1 Domain of unknown function (DUF3557) F-box-like PF12937.2 KLO18495.1 - 5.7e-05 22.7 0.0 0.00015 21.3 0.0 1.7 1 0 0 1 1 1 1 F-box-like HTH_3 PF01381.17 KLO18495.1 - 0.09 12.6 0.0 0.28 11.0 0.0 1.8 1 0 0 1 1 1 0 Helix-turn-helix F-box-like PF12937.2 KLO18496.1 - 0.02 14.6 0.2 0.053 13.2 0.1 1.8 1 0 0 1 1 1 0 F-box-like LRR_4 PF12799.2 KLO18496.1 - 0.09 12.4 1.5 15 5.3 0.0 4.2 5 0 0 5 5 5 0 Leucine Rich repeats (2 copies) Methyltransf_25 PF13649.1 KLO18497.1 - 1e-05 25.8 0.1 0.00011 22.5 0.1 2.4 1 1 0 1 1 1 1 Methyltransferase domain F-box-like PF12937.2 KLO18499.1 - 1.3e-07 31.1 0.0 3.7e-07 29.7 0.0 1.8 1 0 0 1 1 1 1 F-box-like F-box-like PF12937.2 KLO18500.1 - 4.2e-08 32.7 0.5 2.3e-07 30.4 0.1 2.3 2 0 0 2 2 2 1 F-box-like F-box-like PF12937.2 KLO18501.1 - 3.1e-07 30.0 0.9 3.7e-06 26.5 0.2 2.9 2 0 0 2 2 2 1 F-box-like F-box-like PF12937.2 KLO18502.1 - 2.6e-08 33.4 0.1 9.3e-08 31.6 0.1 2.0 1 0 0 1 1 1 1 F-box-like F-box-like PF12937.2 KLO18506.1 - 0.15 11.8 5.0 0.73 9.5 0.1 3.0 3 0 0 3 3 3 0 F-box-like UvrD_C_2 PF13538.1 KLO18509.1 - 0.0053 16.8 0.0 0.012 15.7 0.0 1.5 1 1 0 1 1 1 1 UvrD-like helicase C-terminal domain Myb_DNA-bind_6 PF13921.1 KLO18509.1 - 0.061 13.4 0.4 0.11 12.6 0.2 1.4 1 0 0 1 1 1 0 Myb-like DNA-binding domain F-box PF00646.28 KLO18512.1 - 2.3e-05 23.9 1.7 0.00052 19.5 0.1 2.9 2 0 0 2 2 2 2 F-box domain F-box PF00646.28 KLO18513.1 - 0.00012 21.6 0.8 0.00033 20.2 0.1 2.1 2 0 0 2 2 2 1 F-box domain DUF423 PF04241.10 KLO18514.1 - 0.051 13.4 0.1 0.092 12.6 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF423) ArfGap PF01412.13 KLO18515.1 - 0.0043 16.8 2.2 0.049 13.4 0.2 2.6 2 0 0 2 2 2 1 Putative GTPase activating protein for Arf F-box PF00646.28 KLO18515.1 - 0.006 16.2 0.0 0.015 14.9 0.0 1.7 1 0 0 1 1 1 1 F-box domain DSBA PF01323.15 KLO18516.1 - 1.3e-22 80.2 0.0 1.7e-22 79.9 0.0 1.1 1 0 0 1 1 1 1 DSBA-like thioredoxin domain DUF1767 PF08585.7 KLO18516.1 - 0.0079 16.4 0.0 2.3 8.5 0.0 2.4 2 0 0 2 2 2 2 Domain of unknown function (DUF1767) F-box PF00646.28 KLO18517.1 - 1.2e-06 28.0 0.1 2.1e-06 27.1 0.1 1.4 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 KLO18517.1 - 0.013 15.1 0.0 0.02 14.5 0.0 1.3 1 0 0 1 1 1 0 F-box-like Fork_head PF00250.13 KLO18518.1 - 0.062 13.3 0.0 0.1 12.6 0.0 1.3 1 0 0 1 1 1 0 Fork head domain F-box PF00646.28 KLO18519.1 - 3.6e-05 23.2 0.4 9.3e-05 21.9 0.2 1.7 1 0 0 1 1 1 1 F-box domain F-box PF00646.28 KLO18520.1 - 3.5e-06 26.5 0.1 1.3e-05 24.6 0.1 2.0 1 0 0 1 1 1 1 F-box domain DUF4096 PF13340.1 KLO18520.1 - 0.054 13.3 0.8 21 5.0 0.0 3.6 3 0 0 3 3 3 0 Putative transposase of IS4/5 family (DUF4096) zf-C4_ClpX PF06689.8 KLO18521.1 - 0.00014 21.3 0.9 0.0003 20.2 0.6 1.6 1 0 0 1 1 1 1 ClpX C4-type zinc finger F-box PF00646.28 KLO18521.1 - 0.0033 17.0 0.1 0.024 14.2 0.0 2.5 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.2 KLO18521.1 - 0.061 13.0 0.0 0.26 11.0 0.0 2.1 2 0 0 2 2 2 0 F-box-like zf-C3HC4_2 PF13923.1 KLO18521.1 - 0.61 10.1 6.6 9.2 6.3 1.3 2.7 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Latarcin PF10279.4 KLO18521.1 - 1.6 8.9 4.8 0.32 11.1 0.1 2.3 3 1 0 3 3 3 0 Latarcin precursor Peptidase_M1 PF01433.15 KLO18524.1 - 5.4e-116 387.8 0.0 7.9e-116 387.3 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M1 ERAP1_C PF11838.3 KLO18524.1 - 1.9e-57 194.9 0.0 2.6e-57 194.5 0.0 1.2 1 0 0 1 1 1 1 ERAP1-like C-terminal domain Peptidase_MA_2 PF13485.1 KLO18524.1 - 2.4e-14 53.4 0.3 9.4e-14 51.5 0.0 2.1 2 0 0 2 2 2 1 Peptidase MA superfamily MFS_1 PF07690.11 KLO18525.1 - 1.3e-33 116.1 31.9 1.7e-33 115.8 22.1 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF1228 PF06779.9 KLO18525.1 - 0.00013 21.9 1.0 0.00013 21.9 0.7 3.3 3 0 0 3 3 3 1 Protein of unknown function (DUF1228) DUF485 PF04341.7 KLO18525.1 - 0.37 10.5 0.1 0.37 10.5 0.0 3.3 3 1 1 4 4 4 0 Protein of unknown function, DUF485 Peptidase_M20 PF01546.23 KLO18526.1 - 1.4e-09 37.7 4.6 3.1e-09 36.6 3.2 1.6 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 KLO18526.1 - 5e-08 32.6 0.0 1.4e-07 31.1 0.0 1.8 1 0 0 1 1 1 1 Peptidase dimerisation domain HECT PF00632.20 KLO18527.1 - 2.2e-90 303.0 0.0 2.7e-90 302.7 0.0 1.1 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) WW PF00397.21 KLO18527.1 - 2.5e-31 107.1 15.3 6e-12 45.1 1.1 3.4 3 0 0 3 3 3 3 WW domain Sfi1 PF08457.5 KLO18528.1 - 9.5e-27 93.6 110.2 7.9e-16 57.5 31.8 4.6 1 1 2 3 3 3 3 Sfi1 spindle body protein DUF1770 PF08589.5 KLO18528.1 - 0.02 15.4 2.6 0.02 15.4 1.8 2.2 2 0 0 2 2 2 0 Fungal protein of unknown function (DUF1770) CLTH PF10607.4 KLO18529.1 - 4.4e-20 71.8 0.0 1.2e-19 70.4 0.0 1.7 2 0 0 2 2 2 1 CTLH/CRA C-terminal to LisH motif domain zf-RING_UBOX PF13445.1 KLO18529.1 - 7.3e-16 57.6 2.1 1.7e-15 56.4 1.5 1.7 1 0 0 1 1 1 1 RING-type zinc-finger Rtf2 PF04641.7 KLO18529.1 - 0.0002 20.6 0.1 0.0002 20.6 0.1 1.7 2 0 0 2 2 2 1 Rtf2 RING-finger zf-RING_2 PF13639.1 KLO18529.1 - 0.0015 18.2 1.2 0.0029 17.3 0.9 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 KLO18529.1 - 0.017 14.8 2.2 0.03 13.9 1.6 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KLO18529.1 - 0.025 14.2 2.0 0.047 13.3 1.4 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KLO18529.1 - 0.026 14.2 1.3 0.054 13.2 0.9 1.5 1 0 0 1 1 1 0 zinc-RING finger domain zf-C3HC4_4 PF15227.1 KLO18529.1 - 0.027 14.3 2.1 0.057 13.3 1.4 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-Nse PF11789.3 KLO18529.1 - 0.031 13.8 2.9 0.065 12.7 2.0 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-C3HC4_2 PF13923.1 KLO18529.1 - 0.044 13.8 2.0 0.08 12.9 1.4 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Pkinase PF00069.20 KLO18530.1 - 9.3e-10 38.0 0.2 3e-09 36.4 0.1 1.8 1 1 0 1 1 1 1 Protein kinase domain Kdo PF06293.9 KLO18530.1 - 0.00052 19.1 0.0 0.0011 18.1 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Rpp20 PF12328.3 KLO18532.1 - 3.4e-06 26.7 0.0 5.4e-05 22.8 0.0 1.9 1 1 1 2 2 2 1 Rpp20 subunit of nuclear RNase MRP and P Alba PF01918.16 KLO18532.1 - 0.0038 16.7 0.0 0.0063 16.0 0.0 1.4 1 0 0 1 1 1 1 Alba Biotin_lipoyl PF00364.17 KLO18533.1 - 7e-18 64.0 0.7 1.5e-17 62.9 0.5 1.6 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.12 KLO18533.1 - 7.5e-08 31.8 0.0 1.7e-07 30.7 0.0 1.6 1 0 0 1 1 1 1 e3 binding domain Biotin_lipoyl_2 PF13533.1 KLO18533.1 - 0.016 14.8 0.2 0.49 10.0 0.0 2.9 3 0 0 3 3 3 0 Biotin-lipoyl like Sterol-sensing PF12349.3 KLO18534.1 - 2e-34 118.2 6.2 4.8e-34 117.0 4.3 1.6 1 0 0 1 1 1 1 Sterol-sensing domain of SREBP cleavage-activation Patched PF02460.13 KLO18534.1 - 6.2e-14 50.8 0.0 1e-13 50.1 0.0 1.3 1 0 0 1 1 1 1 Patched family Rad1 PF02144.11 KLO18535.1 - 2.9e-75 252.6 0.0 3.3e-75 252.4 0.0 1.0 1 0 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 PCNA_N PF00705.13 KLO18535.1 - 0.0017 17.8 0.0 0.32 10.4 0.0 2.4 2 0 0 2 2 2 2 Proliferating cell nuclear antigen, N-terminal domain HECA PF15353.1 KLO18535.1 - 0.026 14.2 0.0 0.043 13.5 0.0 1.3 1 0 0 1 1 1 0 Headcase protein family homologue Lysine_decarbox PF03641.9 KLO18536.1 - 5.3e-35 120.1 0.0 7.9e-35 119.5 0.0 1.2 1 0 0 1 1 1 1 Possible lysine decarboxylase Peptidase_M41 PF01434.13 KLO18537.1 - 2.9e-66 222.9 2.4 4.8e-66 222.2 1.7 1.4 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.24 KLO18537.1 - 9.8e-42 142.2 0.1 2.4e-41 141.0 0.0 1.8 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 KLO18537.1 - 5.6e-05 23.2 6.1 0.018 15.0 0.1 3.8 3 2 1 4 4 4 1 AAA ATPase domain AAA_17 PF13207.1 KLO18537.1 - 9.9e-05 23.1 0.0 0.00031 21.5 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.1 KLO18537.1 - 0.00035 20.0 2.1 0.11 11.8 0.6 3.0 1 1 1 2 2 2 2 AAA domain TIP49 PF06068.8 KLO18537.1 - 0.00038 19.3 0.0 0.00077 18.2 0.0 1.4 1 0 0 1 1 1 1 TIP49 C-terminus AAA_22 PF13401.1 KLO18537.1 - 0.00048 20.2 1.2 0.035 14.2 0.8 2.9 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.7 KLO18537.1 - 0.0012 17.9 0.0 0.0033 16.5 0.0 1.7 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_5 PF07728.9 KLO18537.1 - 0.0013 18.4 0.2 0.0062 16.2 0.1 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) Zeta_toxin PF06414.7 KLO18537.1 - 0.0014 17.7 0.1 0.0075 15.3 0.0 2.4 2 0 0 2 2 2 1 Zeta toxin AAA_19 PF13245.1 KLO18537.1 - 0.0021 17.7 0.4 0.0072 16.0 0.3 2.0 1 0 0 1 1 1 1 Part of AAA domain AAA_2 PF07724.9 KLO18537.1 - 0.0039 17.1 0.0 0.011 15.5 0.0 1.8 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_28 PF13521.1 KLO18537.1 - 0.0047 16.9 0.1 0.014 15.3 0.1 1.8 1 0 0 1 1 1 1 AAA domain NACHT PF05729.7 KLO18537.1 - 0.0072 16.0 0.1 0.26 10.9 0.0 2.5 2 0 0 2 2 2 1 NACHT domain AAA_33 PF13671.1 KLO18537.1 - 0.0083 16.0 0.0 0.026 14.3 0.0 1.9 1 0 0 1 1 1 1 AAA domain DUF815 PF05673.8 KLO18537.1 - 0.0085 15.0 0.0 0.022 13.6 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_14 PF13173.1 KLO18537.1 - 0.012 15.5 0.0 0.28 11.0 0.0 2.4 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.12 KLO18537.1 - 0.019 14.4 0.0 0.041 13.3 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_18 PF13238.1 KLO18537.1 - 0.033 14.5 0.1 0.11 12.7 0.0 2.0 2 0 0 2 2 2 0 AAA domain Mg_chelatase PF01078.16 KLO18537.1 - 0.033 13.3 0.5 0.033 13.3 0.3 2.0 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI KaiC PF06745.8 KLO18537.1 - 0.11 11.5 0.6 0.47 9.5 0.4 2.0 1 1 0 1 1 1 0 KaiC Peptidase_M50B PF13398.1 KLO18537.1 - 1.3 8.3 4.3 0.31 10.3 0.1 1.8 2 0 0 2 2 2 0 Peptidase M50B-like SpoIIE PF07228.7 KLO18538.1 - 8.6e-13 48.4 0.0 1.3e-12 47.8 0.0 1.2 1 0 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) PP2C_2 PF13672.1 KLO18538.1 - 1.7e-05 24.3 0.1 3.5e-05 23.3 0.1 1.4 1 1 0 1 1 1 1 Protein phosphatase 2C DNA_pol3_gamma3 PF12169.3 KLO18538.1 - 0.026 14.2 0.0 0.18 11.5 0.0 2.0 2 0 0 2 2 2 0 DNA polymerase III subunits gamma and tau domain III Peptidase_M49 PF03571.10 KLO18539.1 - 4.9e-198 658.6 0.0 5.8e-198 658.4 0.0 1.0 1 0 0 1 1 1 1 Peptidase family M49 LIM PF00412.17 KLO18540.1 - 4.5e-16 58.6 24.8 4.1e-11 42.7 8.0 4.3 4 1 0 4 4 4 2 LIM domain PRP21_like_P PF12230.3 KLO18540.1 - 0.5 9.8 0.9 0.95 8.9 0.0 1.8 2 0 0 2 2 2 0 Pre-mRNA splicing factor PRP21 like protein Glyoxal_oxid_N PF07250.6 KLO18541.1 - 9.5e-50 168.9 0.0 3e-49 167.3 0.0 1.8 2 0 0 2 2 2 1 Glyoxal oxidase N-terminus DUF1929 PF09118.6 KLO18541.1 - 1.6e-22 79.4 0.1 2.9e-22 78.5 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1929) KH_1 PF00013.24 KLO18542.1 - 5e-05 22.8 1.8 0.00011 21.7 0.5 2.0 2 0 0 2 2 2 1 KH domain DUF3835 PF12927.2 KLO18543.1 - 1e-06 29.5 0.2 1e-06 29.5 0.1 4.6 3 2 0 3 3 3 2 Domain of unknown function (DUF3835) DUF3090 PF11290.3 KLO18543.1 - 2.1 7.7 10.4 1.5 8.2 3.3 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF3090) Fungal_trans PF04082.13 KLO18544.1 - 2.1e-26 92.3 0.0 4.2e-26 91.3 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-DHHC PF01529.15 KLO18546.1 - 2e-37 128.2 0.1 3.5e-37 127.4 0.1 1.4 1 0 0 1 1 1 1 DHHC palmitoyltransferase UQ_con PF00179.21 KLO18547.1 - 1.6e-47 160.4 0.0 1.9e-47 160.2 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 KLO18547.1 - 0.00062 19.5 0.0 0.00071 19.3 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 KLO18547.1 - 0.028 14.3 0.7 0.062 13.2 0.5 1.8 1 1 0 1 1 1 0 RWD domain CBM_1 PF00734.13 KLO18548.1 - 1.6e-10 40.4 13.7 1.6e-10 40.4 9.5 2.8 3 0 0 3 3 3 1 Fungal cellulose binding domain DOMON PF03351.12 KLO18548.1 - 0.0019 18.1 0.3 0.0039 17.0 0.2 1.5 1 0 0 1 1 1 1 DOMON domain Glucan_synthase PF02364.10 KLO18549.1 - 0 1357.8 0.0 0 1357.0 0.0 1.4 1 0 0 1 1 1 1 1,3-beta-glucan synthase component FKS1_dom1 PF14288.1 KLO18549.1 - 4.1e-38 129.8 0.1 4.1e-38 129.8 0.1 1.8 2 0 0 2 2 2 1 1,3-beta-glucan synthase subunit FKS1, domain-1 Proteasome PF00227.21 KLO18550.1 - 2e-50 170.7 0.1 2.4e-50 170.4 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit SnoaL_2 PF12680.2 KLO18551.1 - 0.063 13.6 0.0 0.097 13.0 0.0 1.3 1 0 0 1 1 1 0 SnoaL-like domain adh_short_C2 PF13561.1 KLO18552.1 - 6.9e-27 94.7 0.0 8.4e-27 94.4 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 KLO18552.1 - 7e-25 87.8 0.2 9e-25 87.5 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KLO18552.1 - 1.1e-14 54.4 0.2 1.6e-14 53.9 0.1 1.2 1 0 0 1 1 1 1 KR domain 2OG-FeII_Oxy_2 PF13532.1 KLO18553.1 - 6.9e-35 120.6 0.0 2.7e-33 115.4 0.0 2.1 2 0 0 2 2 2 2 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.15 KLO18553.1 - 0.00039 20.6 0.0 0.00073 19.7 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Cmc1 PF08583.5 KLO18554.1 - 2.7e-11 43.0 3.6 3.4e-11 42.7 2.5 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like GCK PF07802.6 KLO18554.1 - 0.79 9.8 2.9 4 7.6 0.3 2.1 1 1 1 2 2 2 0 GCK domain UCR_14kD PF02271.11 KLO18555.1 - 3.8e-37 126.2 1.8 4.3e-37 126.0 1.2 1.0 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase complex 14kD subunit Ferritin PF00210.19 KLO18555.1 - 0.069 12.8 0.1 0.079 12.7 0.1 1.1 1 0 0 1 1 1 0 Ferritin-like domain NDK PF00334.14 KLO18556.1 - 1.6e-56 189.8 0.0 1.8e-56 189.6 0.0 1.0 1 0 0 1 1 1 1 Nucleoside diphosphate kinase PSI_PsaJ PF01701.13 KLO18556.1 - 0.029 14.1 0.0 0.057 13.1 0.0 1.5 1 0 0 1 1 1 0 Photosystem I reaction centre subunit IX / PsaJ Cytochrom_B561 PF03188.11 KLO18557.1 - 3.4e-11 43.1 2.6 3.4e-11 43.1 1.8 1.9 2 0 0 2 2 2 1 Eukaryotic cytochrome b561 DOMON PF03351.12 KLO18557.1 - 1.4e-06 28.2 0.3 3.2e-06 27.0 0.1 1.7 1 1 0 1 1 1 1 DOMON domain DUF2427 PF10348.4 KLO18557.1 - 0.0073 15.8 10.4 0.018 14.5 3.1 2.8 2 1 1 3 3 3 2 Domain of unknown function (DUF2427) DUF4402 PF14352.1 KLO18557.1 - 0.024 15.1 0.3 0.042 14.3 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4402) DUF420 PF04238.7 KLO18557.1 - 0.98 9.3 11.6 0.38 10.6 3.5 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF420) LETM1 PF07766.8 KLO18558.1 - 2.5e-100 334.9 0.8 2.5e-100 334.9 0.5 1.8 2 0 0 2 2 2 1 LETM1-like protein EF-hand_7 PF13499.1 KLO18558.1 - 6.2e-05 23.0 0.1 0.062 13.4 0.0 3.3 2 1 0 2 2 2 2 EF-hand domain pair SAP PF02037.22 KLO18558.1 - 0.00026 20.4 0.3 0.1 12.1 0.0 3.4 4 0 0 4 4 4 1 SAP domain EF-hand_1 PF00036.27 KLO18558.1 - 0.00094 18.3 0.0 0.23 10.8 0.0 3.1 2 0 0 2 2 2 1 EF hand EF-hand_8 PF13833.1 KLO18558.1 - 0.0039 16.7 0.1 0.018 14.6 0.0 2.2 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.1 KLO18558.1 - 0.0051 16.5 0.1 13 5.9 0.0 3.8 3 0 0 3 3 3 1 EF-hand domain EF-hand_5 PF13202.1 KLO18558.1 - 0.038 13.3 0.0 1.5 8.3 0.0 2.7 2 0 0 2 2 2 0 EF hand Grp1_Fun34_YaaH PF01184.14 KLO18559.1 - 9.6e-30 103.4 18.8 1.3e-29 103.0 13.0 1.1 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family Imm15 PF15590.1 KLO18559.1 - 0.063 12.3 0.0 0.11 11.5 0.0 1.3 1 0 0 1 1 1 0 Immunity protein 15 PIN_4 PF13638.1 KLO18560.1 - 6e-22 78.1 0.3 1.5e-21 76.8 0.2 1.7 1 0 0 1 1 1 1 PIN domain EST1_DNA_bind PF10373.4 KLO18560.1 - 7.6e-11 41.7 0.0 2.4e-10 40.0 0.0 1.9 1 0 0 1 1 1 1 Est1 DNA/RNA binding domain Robl_LC7 PF03259.12 KLO18560.1 - 0.0056 16.2 0.7 0.3 10.7 0.1 2.7 2 0 0 2 2 2 1 Roadblock/LC7 domain PTCB-BRCT PF12738.2 KLO18561.1 - 3.9e-34 116.3 0.5 1.5e-11 43.9 0.1 3.7 4 0 0 4 4 4 3 twin BRCT domain BRCT PF00533.21 KLO18561.1 - 1e-27 96.0 0.3 1.4e-08 34.7 0.0 4.3 4 0 0 4 4 4 4 BRCA1 C Terminus (BRCT) domain Ribosomal_L30 PF00327.15 KLO18562.1 - 1.2e-09 37.5 0.0 2e-09 36.8 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L30p/L7e DUF2576 PF10845.3 KLO18562.1 - 0.15 11.2 0.8 0.3 10.2 0.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2576) Transcrip_reg PF01709.15 KLO18563.1 - 3e-57 193.4 0.0 3.5e-57 193.2 0.0 1.0 1 0 0 1 1 1 1 Transcriptional regulator WD40 PF00400.27 KLO18564.1 - 1.6e-34 116.5 18.0 4.4e-12 45.3 0.0 5.9 6 0 0 6 6 6 5 WD domain, G-beta repeat Arch_ATPase PF01637.13 KLO18565.1 - 1.1e-13 51.4 0.0 3.5e-06 26.8 0.0 2.3 2 0 0 2 2 2 2 Archaeal ATPase AAA_16 PF13191.1 KLO18565.1 - 2.7e-08 33.9 0.0 9e-08 32.3 0.0 2.0 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 KLO18565.1 - 0.0014 18.8 0.0 0.09 12.9 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA PF00004.24 KLO18565.1 - 0.004 17.3 0.0 2.1 8.5 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RNA12 PF10443.4 KLO18565.1 - 0.049 12.1 0.0 0.077 11.4 0.0 1.3 1 0 0 1 1 1 0 RNA12 protein AAA_14 PF13173.1 KLO18565.1 - 0.053 13.4 0.0 1.2 9.0 0.0 2.3 2 0 0 2 2 2 0 AAA domain DUF258 PF03193.11 KLO18565.1 - 0.079 12.1 0.0 0.14 11.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_28 PF13521.1 KLO18565.1 - 0.085 12.8 0.0 0.65 9.9 0.0 2.2 2 0 0 2 2 2 0 AAA domain DDE_5 PF13546.1 KLO18565.1 - 0.093 11.5 0.0 0.16 10.8 0.0 1.3 1 0 0 1 1 1 0 DDE superfamily endonuclease 4HBT PF03061.17 KLO18566.1 - 1.4e-11 44.3 0.0 2.3e-11 43.6 0.0 1.4 1 0 0 1 1 1 1 Thioesterase superfamily 4HBT_2 PF13279.1 KLO18566.1 - 1.9e-05 25.0 0.0 2.5e-05 24.6 0.0 1.2 1 0 0 1 1 1 1 Thioesterase-like superfamily Acyl-ACP_TE PF01643.12 KLO18566.1 - 0.0021 17.0 0.6 0.0033 16.4 0.4 1.3 1 0 0 1 1 1 1 Acyl-ACP thioesterase DUF1007 PF06226.8 KLO18567.1 - 0.06 13.0 0.0 0.087 12.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1007) Acyltransferase PF01553.16 KLO18568.1 - 1.8e-11 43.6 0.0 4.5e-05 22.8 0.0 2.7 3 0 0 3 3 3 2 Acyltransferase Peptidase_M24 PF00557.19 KLO18570.1 - 2.2e-47 161.3 0.0 2.8e-47 160.9 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 zf-MYND PF01753.13 KLO18570.1 - 0.51 10.2 5.1 1.1 9.1 3.6 1.6 1 0 0 1 1 1 0 MYND finger NYN PF01936.13 KLO18571.1 - 2.5e-26 92.6 0.0 5.1e-26 91.6 0.0 1.5 1 0 0 1 1 1 1 NYN domain Peptidase_M24 PF00557.19 KLO18572.1 - 2.7e-45 154.4 0.1 3.4e-45 154.1 0.1 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 zf-MYND PF01753.13 KLO18572.1 - 0.0006 19.6 3.5 0.0013 18.6 2.4 1.6 1 0 0 1 1 1 1 MYND finger F-box-like PF12937.2 KLO18573.1 - 1e-07 31.5 2.0 2.8e-07 30.1 0.0 2.4 2 0 0 2 2 2 1 F-box-like NYN PF01936.13 KLO18574.1 - 3.5e-25 88.9 0.0 4.2e-25 88.7 0.0 1.0 1 0 0 1 1 1 1 NYN domain Peptidase_S37 PF05576.6 KLO18574.1 - 0.071 11.5 0.0 0.081 11.3 0.0 1.1 1 0 0 1 1 1 0 PS-10 peptidase S37 Sulfate_transp PF00916.15 KLO18575.1 - 6.2e-80 268.1 4.4 6.2e-80 268.1 3.0 1.8 2 0 0 2 2 2 1 Sulfate transporter family Sulfate_tra_GLY PF13792.1 KLO18575.1 - 5.8e-32 109.2 4.8 5.8e-32 109.2 3.3 2.7 3 0 0 3 3 3 1 Sulfate transporter N-terminal domain with GLY motif STAS PF01740.16 KLO18575.1 - 4.2e-11 42.3 0.0 8.2e-11 41.3 0.0 1.4 1 0 0 1 1 1 1 STAS domain STAS_2 PF13466.1 KLO18575.1 - 0.024 14.6 0.0 0.056 13.4 0.0 1.6 1 0 0 1 1 1 0 STAS domain Peptidase_M1 PF01433.15 KLO18576.1 - 1.2e-105 353.8 0.1 1.8e-105 353.2 0.1 1.3 1 0 0 1 1 1 1 Peptidase family M1 ERAP1_C PF11838.3 KLO18576.1 - 1.3e-39 136.3 0.0 5.7e-39 134.2 0.0 1.9 1 1 0 1 1 1 1 ERAP1-like C-terminal domain Peptidase_MA_2 PF13485.1 KLO18576.1 - 4.2e-11 42.9 0.1 9.2e-11 41.8 0.1 1.5 1 0 0 1 1 1 1 Peptidase MA superfamily NAC PF01849.13 KLO18577.1 - 5.1e-21 73.9 0.0 8.1e-21 73.3 0.0 1.3 1 0 0 1 1 1 1 NAC domain UBA PF00627.26 KLO18577.1 - 0.01 15.6 0.1 0.01 15.6 0.1 2.0 3 0 0 3 3 3 1 UBA/TS-N domain DUF3665 PF12427.3 KLO18577.1 - 0.25 10.7 1.0 2 7.8 0.1 2.3 2 0 0 2 2 2 0 Branched-chain amino acid aminotransferase Glyco_tran_28_C PF04101.11 KLO18578.1 - 1.7e-27 96.0 0.0 2.1e-27 95.8 0.0 1.0 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain Glyco_trans_1_3 PF13528.1 KLO18578.1 - 2.5e-07 30.2 0.0 2.7e-07 30.0 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 1 CLASP_N PF12348.3 KLO18579.1 - 6.1e-29 100.9 0.0 2.6e-10 40.0 0.1 6.0 6 0 0 6 6 6 4 CLASP N terminal HEAT_2 PF13646.1 KLO18579.1 - 5.8e-17 61.7 15.8 0.014 15.6 0.0 9.5 8 1 1 9 9 9 5 HEAT repeats HEAT PF02985.17 KLO18579.1 - 2e-14 52.3 14.5 0.049 13.7 0.0 11.5 11 0 0 11 11 11 4 HEAT repeat Cnd1 PF12717.2 KLO18579.1 - 0.00012 21.9 0.0 4.3 7.1 0.0 5.2 5 0 0 5 5 5 1 non-SMC mitotic condensation complex subunit 1 Cohesin_HEAT PF12765.2 KLO18579.1 - 0.00018 21.3 1.6 1.2 9.2 0.0 5.6 6 0 0 6 6 6 1 HEAT repeat associated with sister chromatid cohesion Adaptin_N PF01602.15 KLO18579.1 - 0.00081 17.8 0.1 1.5 7.0 0.0 4.4 5 0 0 5 5 5 1 Adaptin N terminal region Proteasom_PSMB PF10508.4 KLO18579.1 - 0.0044 15.3 0.1 0.088 11.0 0.0 2.8 3 0 0 3 3 3 1 Proteasome non-ATPase 26S subunit HEAT_EZ PF13513.1 KLO18579.1 - 0.025 15.0 17.9 11 6.6 0.0 9.0 8 2 2 10 10 9 0 HEAT-like repeat TAN PF11640.3 KLO18579.1 - 0.031 13.9 2.3 10 5.8 0.0 4.5 6 0 0 6 6 5 0 Telomere-length maintenance and DNA damage repair Ipi1_N PF12333.3 KLO18579.1 - 0.068 13.1 0.0 4.7 7.2 0.0 3.6 3 0 0 3 3 3 0 Rix1 complex component involved in 60S ribosome maturation MMS19_N PF14500.1 KLO18579.1 - 0.21 10.8 0.4 5.4 6.1 0.0 3.4 3 1 0 3 3 3 0 Dos2-interacting transcription regulator of RNA-Pol-II Nipped-B_C PF12830.2 KLO18579.1 - 0.22 11.1 0.0 20 4.7 0.0 3.4 3 0 0 3 3 3 0 Sister chromatid cohesion C-terminus IF-2B PF01008.12 KLO18581.1 - 4.3e-57 193.2 0.0 5.1e-57 193.0 0.0 1.1 1 0 0 1 1 1 1 Initiation factor 2 subunit family Cyclin_N PF00134.18 KLO18582.1 - 4e-17 61.9 0.1 5.4e-17 61.5 0.1 1.2 1 0 0 1 1 1 1 Cyclin, N-terminal domain TFIIB PF00382.14 KLO18582.1 - 1.2e-06 28.2 0.0 2e-06 27.4 0.0 1.4 1 0 0 1 1 1 1 Transcription factor TFIIB repeat Cyclin_C PF02984.14 KLO18582.1 - 0.071 13.0 0.1 0.13 12.2 0.1 1.5 1 0 0 1 1 1 0 Cyclin, C-terminal domain RWD PF05773.17 KLO18583.1 - 1.2e-18 67.0 0.9 1.2e-18 67.0 0.6 1.6 2 0 0 2 2 2 1 RWD domain Spc7_C2 PF15577.1 KLO18583.1 - 0.012 15.2 0.0 0.03 13.9 0.0 1.6 1 0 0 1 1 1 0 Spc7_C2 Ribosomal_S21 PF01165.15 KLO18584.1 - 7.2e-13 47.7 5.1 1.9e-12 46.4 3.5 1.7 1 0 0 1 1 1 1 Ribosomal protein S21 DUF4211 PF13926.1 KLO18584.1 - 0.09 12.1 1.2 0.17 11.2 0.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4211) Rab3-GTPase_cat PF13890.1 KLO18586.1 - 0.007 15.7 0.0 0.4 10.0 0.0 2.3 2 0 0 2 2 2 2 Rab3 GTPase-activating protein catalytic subunit Abhydrolase_6 PF12697.2 KLO18587.1 - 1.2e-12 48.1 0.4 1.7e-12 47.6 0.3 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KLO18587.1 - 4.8e-06 26.3 0.1 8.8e-05 22.1 0.1 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KLO18587.1 - 0.0046 16.7 0.1 0.019 14.6 0.1 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family SET PF00856.23 KLO18588.1 - 1.2e-05 25.6 0.0 7.6e-05 23.0 0.0 2.1 2 1 0 2 2 2 1 SET domain HEAT_2 PF13646.1 KLO18589.1 - 6.1e-13 48.8 9.1 0.0088 16.3 0.0 7.1 3 2 3 6 6 6 5 HEAT repeats HEAT PF02985.17 KLO18589.1 - 3.4e-12 45.3 25.1 0.0037 17.2 0.1 9.7 10 0 0 10 10 10 4 HEAT repeat Arm PF00514.18 KLO18589.1 - 2.2e-10 39.9 22.6 0.00055 19.6 0.2 9.0 10 0 0 10 10 10 4 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.1 KLO18589.1 - 4.8e-10 39.6 14.1 0.026 15.0 0.4 7.6 8 1 0 8 8 8 3 HEAT-like repeat V-ATPase_H_N PF03224.9 KLO18589.1 - 0.00013 21.1 0.6 0.00076 18.6 0.0 2.3 2 1 0 2 2 2 1 V-ATPase subunit H V-ATPase_H_C PF11698.3 KLO18589.1 - 0.00015 21.6 7.0 0.42 10.5 0.1 4.3 6 0 0 6 6 6 3 V-ATPase subunit H MMS19_N PF14500.1 KLO18589.1 - 0.031 13.5 2.9 1.2 8.3 0.1 3.1 2 1 0 2 2 2 0 Dos2-interacting transcription regulator of RNA-Pol-II TFCD_C PF12612.3 KLO18589.1 - 0.055 12.8 2.7 27 4.0 0.0 4.2 4 0 0 4 4 4 0 Tubulin folding cofactor D C terminal CoaE PF01121.15 KLO18590.1 - 1.5e-65 219.9 0.0 1.8e-65 219.7 0.0 1.0 1 0 0 1 1 1 1 Dephospho-CoA kinase AAA_17 PF13207.1 KLO18590.1 - 8.3e-06 26.6 0.1 1.6e-05 25.6 0.1 1.7 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 KLO18590.1 - 4.9e-05 23.6 0.1 0.00022 21.4 0.1 1.9 1 1 0 1 1 1 1 AAA domain AAA_28 PF13521.1 KLO18590.1 - 0.0029 17.5 0.1 0.0062 16.5 0.0 1.5 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.1 KLO18590.1 - 0.0032 17.3 0.1 0.12 12.2 0.0 2.5 2 1 0 2 2 2 1 AAA domain HSF_DNA-bind PF00447.12 KLO18591.1 - 5.6e-37 126.0 0.6 1e-36 125.2 0.4 1.4 1 0 0 1 1 1 1 HSF-type DNA-binding Tnp_P_element PF12017.3 KLO18591.1 - 0.022 14.0 0.0 0.035 13.3 0.0 1.2 1 0 0 1 1 1 0 Transposase protein DUF904 PF06005.7 KLO18591.1 - 0.032 14.5 0.6 0.056 13.7 0.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF904) Ets PF00178.17 KLO18591.1 - 0.12 12.5 0.1 0.33 11.1 0.0 1.8 2 0 0 2 2 2 0 Ets-domain Arrestin_C PF02752.17 KLO18592.1 - 2e-11 44.1 0.0 9.6e-09 35.4 0.0 2.4 2 0 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain LDB19 PF13002.2 KLO18592.1 - 7e-06 25.6 0.0 0.00017 21.1 0.0 2.2 2 0 0 2 2 2 1 Arrestin_N terminal like Arrestin_N PF00339.24 KLO18592.1 - 6.7e-05 22.7 0.0 0.0013 18.5 0.0 2.6 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain DUF382 PF04037.8 KLO18594.1 - 8.6e-62 206.6 0.4 2.8e-61 205.0 0.2 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF382) PSP PF04046.11 KLO18594.1 - 1.1e-18 66.3 6.3 2.1e-18 65.4 4.4 1.5 1 0 0 1 1 1 1 PSP BSP_II PF05432.6 KLO18594.1 - 0.12 11.5 15.3 0.15 11.3 4.2 2.6 2 0 0 2 2 2 0 Bone sialoprotein II (BSP-II) MitMem_reg PF13012.1 KLO18596.1 - 1e-37 128.6 0.1 1.7e-37 128.0 0.1 1.3 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function JAB PF01398.16 KLO18596.1 - 3.2e-28 97.7 0.0 7.2e-28 96.6 0.0 1.6 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease CNH PF00780.17 KLO18597.1 - 8.5e-25 87.6 0.0 1.4e-24 87.0 0.0 1.2 1 0 0 1 1 1 1 CNH domain RhoGEF PF00621.15 KLO18597.1 - 1.2e-12 48.1 0.0 2.6e-07 30.6 0.0 2.5 2 0 0 2 2 2 2 RhoGEF domain Rtt106 PF08512.7 KLO18597.1 - 0.049 13.6 0.1 0.31 11.0 0.0 2.2 2 0 0 2 2 2 0 Histone chaperone Rttp106-like Pkinase_Tyr PF07714.12 KLO18597.1 - 0.084 11.9 0.0 0.18 10.8 0.0 1.5 1 0 0 1 1 1 0 Protein tyrosine kinase PH_5 PF15405.1 KLO18597.1 - 0.1 12.5 0.0 0.94 9.4 0.0 2.3 1 1 1 2 2 2 0 Pleckstrin homology domain PMT PF02366.13 KLO18599.1 - 8e-76 254.6 17.0 8e-76 254.6 11.8 2.4 2 1 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase MIR PF02815.14 KLO18599.1 - 4.8e-31 107.7 0.6 6.4e-31 107.3 0.4 1.2 1 0 0 1 1 1 1 MIR domain Fibrillarin PF01269.12 KLO18600.1 - 5.3e-108 359.2 0.0 6.4e-108 358.9 0.0 1.0 1 0 0 1 1 1 1 Fibrillarin GCD14 PF08704.5 KLO18600.1 - 0.00014 21.4 0.1 0.00027 20.5 0.0 1.3 1 1 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit Methyltransf_31 PF13847.1 KLO18600.1 - 0.14 11.7 0.0 0.2 11.2 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain DnaJ PF00226.26 KLO18601.1 - 1.8e-21 75.6 1.6 1.8e-21 75.6 1.1 3.0 3 1 0 3 3 3 1 DnaJ domain Lge1 PF11488.3 KLO18601.1 - 3.7 7.7 8.2 0.32 11.2 0.4 3.0 3 1 0 3 3 3 0 Transcriptional regulatory protein LGE1 Ribosomal_S21e PF01249.13 KLO18605.1 - 4.2e-35 119.5 0.0 4.7e-35 119.3 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S21e adh_short PF00106.20 KLO18606.1 - 1.4e-35 122.7 2.4 1.8e-35 122.3 1.6 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KLO18606.1 - 6.8e-16 58.4 0.4 8.9e-16 58.0 0.3 1.1 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 KLO18606.1 - 6.5e-14 52.2 0.1 7.8e-14 52.0 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 KLO18606.1 - 6.1e-06 26.3 0.8 1.5e-05 25.1 0.4 1.5 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 KLO18606.1 - 2.2e-05 24.0 0.2 3.3e-05 23.4 0.1 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 KLO18606.1 - 0.00074 18.5 0.2 0.00099 18.0 0.1 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Eno-Rase_NADH_b PF12242.3 KLO18606.1 - 0.0014 18.3 0.8 0.003 17.3 0.5 1.5 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase 3HCDH_N PF02737.13 KLO18606.1 - 0.01 15.5 1.0 0.016 14.8 0.2 1.7 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DUF1776 PF08643.5 KLO18606.1 - 0.011 14.9 0.0 0.014 14.5 0.0 1.1 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) THF_DHG_CYH_C PF02882.14 KLO18606.1 - 0.017 14.2 0.2 0.043 12.8 0.1 1.7 1 1 1 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain NmrA PF05368.8 KLO18606.1 - 0.055 12.7 1.0 0.09 12.0 0.7 1.4 1 0 0 1 1 1 0 NmrA-like family ApbA PF02558.11 KLO18606.1 - 0.061 12.7 0.1 0.1 12.0 0.1 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA RmlD_sub_bind PF04321.12 KLO18606.1 - 0.093 11.6 0.2 0.22 10.3 0.1 1.7 2 0 0 2 2 2 0 RmlD substrate binding domain adh_short_C2 PF13561.1 KLO18612.1 - 1.1e-15 58.1 0.0 1.3e-15 57.8 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 KLO18612.1 - 5.5e-09 36.1 0.5 1.2e-08 35.1 0.3 1.5 1 1 0 1 1 1 1 short chain dehydrogenase tRNA-synt_2b PF00587.20 KLO18612.1 - 0.052 13.1 0.0 0.081 12.5 0.0 1.2 1 0 0 1 1 1 0 tRNA synthetase class II core domain (G, H, P, S and T) KR PF08659.5 KLO18612.1 - 0.055 13.1 0.5 0.11 12.1 0.2 1.6 2 0 0 2 2 2 0 KR domain Anophelin PF10731.4 KLO18613.1 - 0.062 13.4 0.2 0.22 11.6 0.0 1.9 2 0 0 2 2 2 0 Thrombin inhibitor from mosquito adh_short PF00106.20 KLO18614.1 - 7.8e-14 51.9 0.0 1.7e-13 50.8 0.0 1.6 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KLO18614.1 - 0.00014 21.7 0.0 0.00018 21.3 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KLO18614.1 - 0.00055 19.6 0.0 0.0011 18.7 0.0 1.5 1 0 0 1 1 1 1 KR domain AMP-binding PF00501.23 KLO18615.1 - 8.4e-87 291.2 0.0 1.1e-86 290.8 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 KLO18615.1 - 5.4e-11 43.2 0.1 1.4e-10 41.9 0.1 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain AMP-binding PF00501.23 KLO18616.1 - 7.5e-86 288.1 0.0 9.6e-86 287.7 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 KLO18616.1 - 1e-09 39.1 0.2 2.2e-09 38.1 0.1 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Glyco_transf_22 PF03901.12 KLO18617.1 - 1.1e-94 317.8 26.8 1.3e-94 317.5 18.6 1.0 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family PMT_2 PF13231.1 KLO18617.1 - 2.9e-05 24.0 9.2 2.9e-05 24.0 6.4 2.2 1 1 0 1 1 1 1 Dolichyl-phosphate-mannose-protein mannosyltransferase Amidohydro_1 PF01979.15 KLO18618.1 - 4.6e-44 151.4 0.0 5.7e-44 151.1 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.6 KLO18618.1 - 5.4e-09 35.7 0.0 2.8e-05 23.5 0.0 2.3 2 0 0 2 2 2 2 Amidohydrolase family Amidohydro_5 PF13594.1 KLO18618.1 - 2.5e-06 27.1 0.0 5.9e-06 26.0 0.0 1.7 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_4 PF13147.1 KLO18618.1 - 0.00023 21.3 0.2 0.032 14.2 0.0 2.2 2 0 0 2 2 2 2 Amidohydrolase A_deaminase PF00962.17 KLO18618.1 - 0.049 12.5 0.0 0.076 11.9 0.0 1.3 1 0 0 1 1 1 0 Adenosine/AMP deaminase Lipase_3 PF01764.20 KLO18619.1 - 8.3e-08 31.9 0.0 3.3e-07 29.9 0.0 2.0 1 1 0 1 1 1 1 Lipase (class 3) Abhydrolase_5 PF12695.2 KLO18619.1 - 0.008 15.9 0.0 0.012 15.4 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family UPF0227 PF05728.7 KLO18619.1 - 0.011 15.4 0.1 0.018 14.7 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) PGAP1 PF07819.8 KLO18619.1 - 0.05 13.1 0.0 0.072 12.6 0.0 1.2 1 0 0 1 1 1 0 PGAP1-like protein Abhydrolase_6 PF12697.2 KLO18619.1 - 0.053 13.3 0.2 0.078 12.8 0.1 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family MARVEL PF01284.18 KLO18620.1 - 0.0016 18.3 7.4 0.024 14.4 2.9 2.2 2 0 0 2 2 2 2 Membrane-associating domain CTP_transf_2 PF01467.21 KLO18622.1 - 3.5e-10 40.1 0.0 5.6e-10 39.4 0.0 1.4 1 0 0 1 1 1 1 Cytidylyltransferase FAD_syn PF06574.7 KLO18622.1 - 0.036 13.6 0.0 0.072 12.7 0.0 1.5 1 0 0 1 1 1 0 FAD synthetase DUF3717 PF12512.3 KLO18623.1 - 0.15 11.7 0.1 0.51 10.0 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3717) mRNA_cap_enzyme PF01331.14 KLO18624.1 - 1.7e-48 164.8 0.1 2.3e-48 164.4 0.1 1.2 1 0 0 1 1 1 1 mRNA capping enzyme, catalytic domain mRNA_cap_C PF03919.10 KLO18624.1 - 3.8e-18 65.7 0.0 6.5e-18 64.9 0.0 1.4 1 0 0 1 1 1 1 mRNA capping enzyme, C-terminal domain DNA_ligase_A_M PF01068.16 KLO18624.1 - 6.6e-08 32.1 0.0 2.3e-06 27.1 0.0 2.3 1 1 0 1 1 1 1 ATP dependent DNA ligase domain Skp1 PF01466.14 KLO18625.1 - 9.3e-39 131.3 1.8 1.8e-38 130.4 1.2 1.5 1 0 0 1 1 1 1 Skp1 family, dimerisation domain Skp1_POZ PF03931.10 KLO18625.1 - 1.3e-26 92.4 0.4 3.5e-26 91.0 0.1 1.9 2 0 0 2 2 2 1 Skp1 family, tetramerisation domain BTB PF00651.26 KLO18625.1 - 0.0015 18.4 0.0 0.033 14.1 0.0 2.2 1 1 0 1 1 1 1 BTB/POZ domain Ribosomal_L27 PF01016.14 KLO18626.1 - 6.9e-33 112.2 0.8 9.4e-33 111.8 0.5 1.2 1 0 0 1 1 1 1 Ribosomal L27 protein DEAD PF00270.24 KLO18627.1 - 9e-37 126.1 0.0 2.2e-36 124.9 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KLO18627.1 - 1.2e-20 73.1 0.0 2.5e-20 72.1 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF4217 PF13959.1 KLO18627.1 - 1.4e-20 72.6 0.0 3.4e-20 71.3 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.10 KLO18627.1 - 7.1e-05 22.7 3.1 0.00024 20.9 0.0 2.7 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_22 PF13401.1 KLO18627.1 - 0.016 15.3 0.1 0.15 12.1 0.1 2.5 1 1 0 1 1 1 0 AAA domain Borrelia_P83 PF05262.6 KLO18627.1 - 9.4 4.3 21.4 13 3.8 14.8 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein DUF3074 PF11274.3 KLO18628.1 - 6.3e-37 126.9 0.1 8.9e-37 126.5 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3074) UXS1_N PF11803.3 KLO18628.1 - 0.065 12.9 0.0 0.13 12.0 0.0 1.4 1 0 0 1 1 1 0 UDP-glucuronate decarboxylase N-terminal AAA PF00004.24 KLO18629.1 - 1.9e-44 151.0 0.1 5.9e-44 149.4 0.0 1.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 KLO18629.1 - 2.9e-09 36.7 0.1 8.4e-09 35.2 0.1 1.8 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 KLO18629.1 - 8.9e-08 32.2 0.1 3e-07 30.5 0.0 1.9 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.1 KLO18629.1 - 2.7e-07 30.7 0.1 2e-06 27.9 0.0 2.2 1 1 0 1 1 1 1 AAA ATPase domain DUF815 PF05673.8 KLO18629.1 - 5.6e-06 25.4 0.0 9.9e-06 24.6 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_22 PF13401.1 KLO18629.1 - 1.9e-05 24.7 4.2 0.0004 20.5 0.4 3.0 3 1 0 3 3 1 1 AAA domain AAA_14 PF13173.1 KLO18629.1 - 8.2e-05 22.5 0.0 0.00047 20.0 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.1 KLO18629.1 - 0.00016 21.6 0.0 0.00039 20.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 KLO18629.1 - 0.00017 21.2 0.1 0.00043 19.9 0.1 1.6 1 0 0 1 1 1 1 Part of AAA domain AAA_17 PF13207.1 KLO18629.1 - 0.00039 21.2 0.0 0.0038 18.0 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.1 KLO18629.1 - 0.00064 19.1 0.8 0.013 14.9 0.0 2.4 1 1 1 2 2 2 1 AAA domain RuvB_N PF05496.7 KLO18629.1 - 0.00073 18.6 0.0 0.0016 17.5 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus RNA_helicase PF00910.17 KLO18629.1 - 0.00074 19.6 0.0 0.0043 17.2 0.0 2.1 2 0 0 2 2 2 1 RNA helicase TIP49 PF06068.8 KLO18629.1 - 0.00097 17.9 0.0 0.0019 16.9 0.0 1.4 1 0 0 1 1 1 1 TIP49 C-terminus NTPase_1 PF03266.10 KLO18629.1 - 0.0012 18.5 0.0 0.0058 16.3 0.0 2.2 2 0 0 2 2 2 1 NTPase NACHT PF05729.7 KLO18629.1 - 0.0016 18.1 0.1 0.054 13.1 0.0 2.4 2 0 0 2 2 2 1 NACHT domain UPF0079 PF02367.12 KLO18629.1 - 0.0022 17.6 0.1 0.019 14.5 0.0 2.2 1 1 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 AAA_11 PF13086.1 KLO18629.1 - 0.0031 17.1 0.2 0.019 14.5 0.0 2.1 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.12 KLO18629.1 - 0.0036 16.7 0.0 0.0098 15.3 0.0 1.7 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_18 PF13238.1 KLO18629.1 - 0.0037 17.5 0.1 0.075 13.3 0.0 2.4 2 1 0 2 2 2 1 AAA domain Mg_chelatase PF01078.16 KLO18629.1 - 0.0069 15.5 0.0 0.016 14.4 0.0 1.6 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.6 KLO18629.1 - 0.007 15.9 0.0 0.017 14.7 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.1 KLO18629.1 - 0.0083 15.9 0.0 0.017 14.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain Arch_ATPase PF01637.13 KLO18629.1 - 0.0085 15.8 2.6 0.23 11.1 0.0 3.0 2 1 1 3 3 3 1 Archaeal ATPase AAA_30 PF13604.1 KLO18629.1 - 0.011 15.2 0.0 0.023 14.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.1 KLO18629.1 - 0.016 14.8 0.5 0.033 13.7 0.1 1.7 2 0 0 2 2 1 0 AAA domain Zeta_toxin PF06414.7 KLO18629.1 - 0.023 13.7 0.0 0.041 12.9 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin AFG1_ATPase PF03969.11 KLO18629.1 - 0.036 12.8 0.0 0.076 11.8 0.0 1.6 1 0 0 1 1 1 0 AFG1-like ATPase Bac_DnaA PF00308.13 KLO18629.1 - 0.05 13.2 0.0 0.093 12.3 0.0 1.4 1 0 0 1 1 1 0 Bacterial dnaA protein AAA_23 PF13476.1 KLO18629.1 - 0.065 13.5 7.4 0.74 10.1 0.0 2.3 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.22 KLO18629.1 - 0.067 13.4 0.1 0.67 10.2 0.0 2.5 3 0 0 3 3 2 0 ABC transporter Sigma54_activat PF00158.21 KLO18629.1 - 0.068 12.6 0.2 1.1 8.6 0.0 2.6 3 1 0 3 3 2 0 Sigma-54 interaction domain KaiC PF06745.8 KLO18629.1 - 0.079 12.0 1.3 0.39 9.7 0.0 2.5 3 0 0 3 3 3 0 KaiC Sigma54_activ_2 PF14532.1 KLO18629.1 - 0.11 12.5 0.0 0.58 10.1 0.0 2.2 1 1 0 1 1 1 0 Sigma-54 interaction domain Parvo_NS1 PF01057.12 KLO18629.1 - 0.13 11.1 0.0 0.22 10.3 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Gln-synt_C PF00120.19 KLO18630.1 - 1.6e-54 184.7 0.0 2.7e-53 180.7 0.0 2.1 1 1 0 1 1 1 1 Glutamine synthetase, catalytic domain P5CR_dimer PF14748.1 KLO18631.1 - 3.8e-39 132.9 2.7 4.8e-39 132.6 1.3 1.7 2 0 0 2 2 2 1 Pyrroline-5-carboxylate reductase dimerisation F420_oxidored PF03807.12 KLO18631.1 - 1.7e-11 44.3 0.0 2.5e-08 34.2 0.0 2.6 2 0 0 2 2 2 2 NADP oxidoreductase coenzyme F420-dependent Peptidase_M16 PF00675.15 KLO18632.1 - 3.1e-37 127.6 0.5 1.7e-36 125.2 0.0 2.5 2 1 1 3 3 3 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.16 KLO18632.1 - 1.5e-20 73.6 0.2 2.6e-11 43.5 0.0 3.3 3 0 0 3 3 3 2 Peptidase M16 inactive domain Methyltransf_11 PF08241.7 KLO18633.1 - 9.1e-09 35.7 0.0 1.6e-08 34.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KLO18633.1 - 0.00018 21.1 0.0 0.00027 20.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KLO18633.1 - 0.00031 21.0 0.0 0.00081 19.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KLO18633.1 - 0.0012 18.6 0.0 0.0017 18.1 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KLO18633.1 - 0.013 15.9 0.0 0.028 14.8 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Hydrophobin PF01185.13 KLO18635.1 - 1.4e-05 25.4 5.9 2.1e-05 24.8 4.1 1.3 1 0 0 1 1 1 1 Fungal hydrophobin TPR_MLP1_2 PF07926.7 KLO18638.1 - 0.0059 16.3 8.1 0.0059 16.3 5.6 3.7 1 1 2 3 3 3 2 TPR/MLP1/MLP2-like protein HOOK PF05622.7 KLO18638.1 - 0.83 7.3 37.5 2.4 5.8 26.0 1.7 1 1 0 1 1 1 0 HOOK protein HALZ PF02183.13 KLO18638.1 - 1.8 8.3 12.1 0.051 13.3 1.7 3.6 3 0 0 3 3 3 0 Homeobox associated leucine zipper HSP90 PF00183.13 KLO18639.1 - 7e-258 856.3 35.4 7e-258 856.3 24.5 1.4 2 0 0 2 2 2 1 Hsp90 protein HATPase_c PF02518.21 KLO18639.1 - 1.6e-11 43.8 0.0 3.2e-11 42.9 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.1 KLO18639.1 - 6.9e-11 41.9 0.1 6.9e-11 41.9 0.1 2.2 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Peptidase_C37 PF05416.7 KLO18639.1 - 1.4 7.0 9.1 1.5 7.0 0.0 2.2 2 0 0 2 2 2 0 Southampton virus-type processing peptidase Aminotran_5 PF00266.14 KLO18641.1 - 2.1e-26 92.5 0.0 6.9e-25 87.5 0.0 2.3 1 1 0 1 1 1 1 Aminotransferase class-V Peptidase_C48 PF02902.14 KLO18644.1 - 0.0012 18.4 0.2 0.0039 16.8 0.0 1.9 2 0 0 2 2 2 1 Ulp1 protease family, C-terminal catalytic domain GIDA PF01134.17 KLO18646.1 - 9.8e-148 492.1 0.0 1.3e-147 491.7 0.0 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A GIDA_assoc_3 PF13932.1 KLO18646.1 - 2.5e-16 59.4 0.0 7.2e-16 58.0 0.0 1.8 1 0 0 1 1 1 1 GidA associated domain 3 Pyr_redox_2 PF07992.9 KLO18646.1 - 4.3e-06 26.7 0.1 1.3e-05 25.1 0.0 1.8 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 KLO18646.1 - 7.3e-05 22.0 0.0 0.00019 20.6 0.0 1.8 2 0 0 2 2 2 1 FAD dependent oxidoreductase DAO PF01266.19 KLO18646.1 - 0.00038 19.4 1.4 0.86 8.4 0.0 3.0 3 0 0 3 3 3 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 KLO18646.1 - 0.0025 16.7 0.7 0.0025 16.7 0.5 1.5 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.9 KLO18646.1 - 0.0032 16.0 1.8 0.11 10.9 0.1 2.8 3 0 0 3 3 3 1 HI0933-like protein Pyr_redox PF00070.22 KLO18646.1 - 0.046 14.1 0.2 0.15 12.4 0.1 1.9 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase PROL5-SMR PF15621.1 KLO18646.1 - 0.086 13.2 0.0 0.17 12.2 0.0 1.5 1 0 0 1 1 1 0 Proline-rich submaxillary gland androgen-regulated family Sirohm_synth_C PF14823.1 KLO18646.1 - 0.16 11.2 0.1 0.51 9.6 0.0 1.8 2 0 0 2 2 2 0 Sirohaem biosynthesis protein C-terminal Coatomer_WDAD PF04053.9 KLO18647.1 - 0.0036 16.1 0.0 0.0067 15.2 0.0 1.4 1 0 0 1 1 1 1 Coatomer WD associated region WD40 PF00400.27 KLO18647.1 - 0.0052 16.6 0.7 4.7 7.2 0.0 4.1 4 0 0 4 4 4 1 WD domain, G-beta repeat PD40 PF07676.7 KLO18647.1 - 0.071 12.8 0.5 14 5.4 0.1 2.8 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat Glyco_hydro_3 PF00933.16 KLO18648.1 - 1.3e-89 300.1 0.0 1.7e-89 299.7 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 KLO18648.1 - 1.8e-47 161.7 0.2 1.1e-46 159.1 0.0 2.1 2 0 0 2 2 2 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 KLO18648.1 - 1.8e-21 75.8 0.1 3.1e-21 75.0 0.0 1.4 1 0 0 1 1 1 1 Fibronectin type III-like domain PEMT PF04191.8 KLO18649.1 - 3e-50 168.7 15.2 1.1e-29 102.5 1.2 2.9 3 0 0 3 3 3 2 Phospholipid methyltransferase PID PF00640.18 KLO18649.1 - 0.00061 19.7 0.2 0.0047 16.9 0.0 2.1 2 0 0 2 2 2 1 Phosphotyrosine interaction domain (PTB/PID) DUF4199 PF13858.1 KLO18649.1 - 0.027 14.3 2.9 4.1 7.2 0.0 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF4199) ISG65-75 PF11727.3 KLO18649.1 - 0.045 12.8 0.1 0.079 11.9 0.1 1.3 1 0 0 1 1 1 0 Invariant surface glycoprotein FUN14 PF04930.10 KLO18650.1 - 3.3e-20 72.2 0.4 5.2e-20 71.5 0.0 1.5 2 0 0 2 2 2 1 FUN14 family Nucleoporin2 PF04096.9 KLO18652.1 - 6.9e-45 152.3 0.0 1.6e-44 151.1 0.0 1.6 2 0 0 2 2 2 1 Nucleoporin autopeptidase Nucleoporin_FG PF13634.1 KLO18652.1 - 1e-23 83.7 340.0 3.9e-10 39.9 41.4 10.0 2 2 5 7 7 7 5 Nucleoporin FG repeat region Fes1 PF08609.5 KLO18653.1 - 1.1e-22 80.3 0.5 3.3e-22 78.7 0.2 1.9 2 0 0 2 2 2 1 Nucleotide exchange factor Fes1 HEAT_2 PF13646.1 KLO18653.1 - 2e-05 24.7 0.8 0.0047 17.1 0.1 3.0 1 1 2 3 3 3 2 HEAT repeats HEAT PF02985.17 KLO18653.1 - 7.4e-05 22.5 0.1 0.62 10.2 0.0 3.6 3 0 0 3 3 3 2 HEAT repeat Adaptin_N PF01602.15 KLO18653.1 - 0.0033 15.8 0.1 0.77 8.0 0.0 2.1 1 1 1 2 2 2 2 Adaptin N terminal region HEAT_EZ PF13513.1 KLO18653.1 - 0.098 13.1 0.4 5.6 7.5 0.1 3.0 1 1 1 2 2 2 0 HEAT-like repeat LETM1 PF07766.8 KLO18654.1 - 0.079 11.9 1.2 0.13 11.2 0.9 1.2 1 0 0 1 1 1 0 LETM1-like protein Peroxidase_2 PF01328.12 KLO18655.1 - 3.2e-20 72.0 0.0 4.2e-20 71.6 0.0 1.2 1 0 0 1 1 1 1 Peroxidase, family 2 MaoC_dehydratas PF01575.14 KLO18657.1 - 1.3e-25 89.1 0.0 2.2e-25 88.4 0.0 1.2 1 0 0 1 1 1 1 MaoC like domain MaoC_dehydrat_N PF13452.1 KLO18657.1 - 0.00069 19.4 0.0 0.023 14.4 0.0 2.8 2 2 0 2 2 2 1 N-terminal half of MaoC dehydratase DUF2888 PF11135.3 KLO18657.1 - 0.086 12.5 0.0 0.13 11.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2888) NAD_binding_4 PF07993.7 KLO18658.1 - 1.2e-28 99.7 0.0 1.9e-28 99.0 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.23 KLO18658.1 - 1.4e-26 92.9 0.0 4.7e-25 87.8 0.0 2.1 1 1 0 1 1 1 1 AMP-binding enzyme Epimerase PF01370.16 KLO18658.1 - 2.8e-06 26.9 0.0 6.7e-06 25.7 0.0 1.7 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.20 KLO18658.1 - 6.4e-06 26.3 0.0 1.7e-05 24.9 0.0 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site 3Beta_HSD PF01073.14 KLO18658.1 - 0.00046 18.9 0.0 0.0013 17.4 0.0 1.8 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.20 KLO18658.1 - 0.0076 16.1 0.0 0.56 10.1 0.1 3.1 2 1 0 2 2 2 1 short chain dehydrogenase Isy1 PF06246.7 KLO18660.1 - 1.2e-81 273.8 1.0 1.5e-81 273.5 0.7 1.2 1 0 0 1 1 1 1 Isy1-like splicing family DUF4243 PF14027.1 KLO18661.1 - 1.3e-76 258.1 0.0 1.6e-76 257.8 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4243) Pyr_redox_2 PF07992.9 KLO18662.1 - 2.3e-42 145.1 0.0 3.9e-42 144.4 0.0 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.17 KLO18662.1 - 2.9e-41 139.9 0.1 2.9e-41 139.9 0.1 2.8 4 0 0 4 4 4 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.22 KLO18662.1 - 1.2e-20 73.6 9.1 2.5e-18 66.2 1.2 3.8 5 0 0 5 5 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 KLO18662.1 - 3.5e-12 46.8 0.1 1.7e-08 34.7 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 KLO18662.1 - 1.2e-11 44.3 10.1 2.8e-10 39.8 0.0 3.1 2 1 1 3 3 3 2 FAD dependent oxidoreductase GIDA PF01134.17 KLO18662.1 - 2.5e-09 36.4 9.7 2.5e-08 33.2 2.7 2.9 2 1 0 2 2 2 2 Glucose inhibited division protein A NAD_binding_8 PF13450.1 KLO18662.1 - 1.7e-08 34.3 5.6 0.00012 22.0 0.3 2.6 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain DAO PF01266.19 KLO18662.1 - 1.3e-07 30.8 13.8 0.023 13.6 0.1 4.2 3 1 1 4 4 4 3 FAD dependent oxidoreductase HI0933_like PF03486.9 KLO18662.1 - 1.5e-07 30.3 14.4 9.3e-05 21.0 0.4 4.1 4 0 0 4 4 4 3 HI0933-like protein FAD_binding_2 PF00890.19 KLO18662.1 - 5.8e-07 28.7 1.7 5.8e-07 28.7 1.2 3.8 3 1 0 4 4 4 2 FAD binding domain K_oxygenase PF13434.1 KLO18662.1 - 4.5e-05 22.5 2.3 0.0027 16.6 0.0 2.5 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) AlaDh_PNT_C PF01262.16 KLO18662.1 - 0.00035 20.1 0.6 0.038 13.5 0.0 2.5 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain Thi4 PF01946.12 KLO18662.1 - 0.0005 19.2 6.2 0.0013 17.8 0.0 2.6 2 1 0 2 2 2 1 Thi4 family FAD_binding_3 PF01494.14 KLO18662.1 - 0.0025 16.9 11.4 0.055 12.5 0.3 3.4 3 1 0 3 3 3 2 FAD binding domain Lycopene_cycl PF05834.7 KLO18662.1 - 0.0085 15.0 1.5 0.14 11.0 0.0 2.8 3 0 0 3 3 3 1 Lycopene cyclase protein Mqo PF06039.10 KLO18662.1 - 0.027 12.6 3.0 0.13 10.4 0.1 2.2 1 1 1 2 2 2 0 Malate:quinone oxidoreductase (Mqo) Aldedh PF00171.17 KLO18663.1 - 4.9e-82 275.6 0.0 6e-82 275.4 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Fic PF02661.13 KLO18663.1 - 0.00068 20.2 0.1 0.038 14.6 0.0 2.9 3 0 0 3 3 3 1 Fic/DOC family TFIIE_beta PF02186.10 KLO18663.1 - 0.13 12.3 0.0 0.27 11.2 0.0 1.5 1 0 0 1 1 1 0 TFIIE beta subunit core domain DUF3808 PF10300.4 KLO18664.1 - 1.3e-80 271.3 0.0 2.2e-80 270.5 0.0 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF3808) TPR_11 PF13414.1 KLO18664.1 - 9e-05 22.0 9.0 0.078 12.6 0.3 3.9 3 1 1 4 4 4 3 TPR repeat TPR_12 PF13424.1 KLO18664.1 - 0.0014 18.5 6.5 0.44 10.5 0.1 3.9 3 1 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.12 KLO18664.1 - 0.0026 17.5 7.7 0.18 11.7 0.0 4.3 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_8 PF13181.1 KLO18664.1 - 0.015 15.0 2.0 0.8 9.6 0.0 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_16 PF13432.1 KLO18664.1 - 0.03 14.9 2.6 0.92 10.2 0.1 3.8 4 1 1 5 5 5 0 Tetratricopeptide repeat TPR_6 PF13174.1 KLO18664.1 - 0.069 13.6 4.1 1.5e+02 3.2 0.0 5.2 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_1 PF00515.23 KLO18664.1 - 0.24 11.0 6.8 4.3 7.1 0.0 4.3 5 0 0 5 5 5 0 Tetratricopeptide repeat Myb_DNA-binding PF00249.26 KLO18665.1 - 3.3e-06 27.0 0.6 0.00053 19.9 0.0 2.5 2 0 0 2 2 2 1 Myb-like DNA-binding domain DUF1816 PF08846.5 KLO18665.1 - 0.11 12.2 0.1 1.9 8.2 0.0 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF1816) Glyco_hydro_38 PF01074.17 KLO18666.1 - 7.5e-83 277.9 0.2 1.1e-82 277.3 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 N-terminal domain Glyco_hydro_38C PF07748.8 KLO18666.1 - 1.3e-63 215.3 0.0 1.9e-63 214.8 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal domain Alpha-mann_mid PF09261.6 KLO18666.1 - 2.8e-26 91.5 0.0 1.2e-25 89.5 0.0 2.0 2 0 0 2 2 2 1 Alpha mannosidase, middle domain Phage_P2_GpU PF06995.6 KLO18666.1 - 0.14 11.5 0.1 0.56 9.6 0.0 2.1 2 0 0 2 2 2 0 Phage P2 GpU DUF3808 PF10300.4 KLO18667.1 - 2.4e-69 234.1 0.0 3.7e-69 233.5 0.0 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF3808) TPR_12 PF13424.1 KLO18667.1 - 0.0036 17.1 4.1 0.033 14.1 0.2 3.0 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.1 KLO18667.1 - 0.076 13.7 4.3 0.42 11.3 0.1 3.4 2 1 2 4 4 4 0 Tetratricopeptide repeat TPR_2 PF07719.12 KLO18667.1 - 6.7 6.9 8.5 2.9 8.0 0.3 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat p450 PF00067.17 KLO18668.1 - 8.9e-34 116.7 0.0 1.2e-33 116.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 DUF3940 PF13076.1 KLO18668.1 - 0.0043 16.5 0.0 0.34 10.4 0.0 2.8 3 0 0 3 3 3 1 Protein of unknown function (DUF3940) Pkinase PF00069.20 KLO18669.1 - 8.8e-21 74.2 0.0 3.4e-20 72.2 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KLO18669.1 - 1.1e-06 27.9 0.1 0.00018 20.6 0.1 2.9 2 1 0 2 2 2 1 Protein tyrosine kinase Syntaxin-6_N PF09177.6 KLO18670.1 - 0.46 10.9 3.0 0.55 10.6 0.5 2.3 2 0 0 2 2 2 0 Syntaxin 6, N-terminal PCI PF01399.22 KLO18671.1 - 4.8e-16 58.9 0.1 2.1e-15 56.9 0.1 2.1 1 0 0 1 1 1 1 PCI domain DDRGK PF09756.4 KLO18671.1 - 0.018 14.4 0.1 0.018 14.4 0.1 1.6 2 0 0 2 2 2 0 DDRGK domain Peptidase_S28 PF05577.7 KLO18671.1 - 0.11 11.0 0.0 0.2 10.1 0.0 1.4 1 0 0 1 1 1 0 Serine carboxypeptidase S28 TPR_6 PF13174.1 KLO18671.1 - 0.28 11.7 4.6 30 5.3 0.0 4.7 5 0 0 5 5 5 0 Tetratricopeptide repeat Methyltransf_22 PF13383.1 KLO18672.1 - 5.3e-29 101.4 0.0 6.8e-29 101.1 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_21 PF05050.7 KLO18672.1 - 1.7e-05 24.8 0.0 2.6e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase FkbM domain HLH PF00010.21 KLO18673.1 - 9.4e-14 50.8 0.2 1.7e-13 50.0 0.1 1.4 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain NEMO PF11577.3 KLO18673.1 - 0.0016 18.1 0.4 0.0035 17.0 0.3 1.6 1 0 0 1 1 1 1 NF-kappa-B essential modulator NEMO IncA PF04156.9 KLO18673.1 - 0.33 10.5 2.2 0.5 9.9 1.5 1.3 1 0 0 1 1 1 0 IncA protein DUF972 PF06156.8 KLO18673.1 - 0.42 10.9 2.4 0.7 10.2 0.5 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF972) Na_H_Exchanger PF00999.16 KLO18674.1 - 1.5e-68 231.0 36.7 1.9e-68 230.7 25.4 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Methyltransf_23 PF13489.1 KLO18675.1 - 5.2e-15 55.5 0.0 8.7e-15 54.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KLO18675.1 - 2.2e-13 50.0 0.0 2.3e-12 46.7 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KLO18675.1 - 5e-12 46.1 0.0 3.5e-11 43.4 0.0 2.3 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 KLO18675.1 - 8.9e-10 38.9 0.0 5.3e-09 36.4 0.0 2.3 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 KLO18675.1 - 2e-06 28.3 0.1 5.8e-05 23.6 0.1 2.4 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KLO18675.1 - 3.9e-06 26.3 0.0 0.0026 17.1 0.0 2.5 3 0 0 3 3 3 2 Methyltransferase small domain Methyltransf_26 PF13659.1 KLO18675.1 - 1.1e-05 25.4 0.1 7e-05 22.8 0.1 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 KLO18675.1 - 1.6e-05 24.0 0.0 0.00021 20.3 0.0 2.1 2 0 0 2 2 2 1 Putative methyltransferase Methyltransf_25 PF13649.1 KLO18675.1 - 5.4e-05 23.4 0.0 0.00014 22.1 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain GidB PF02527.10 KLO18675.1 - 0.00058 19.0 0.0 0.099 11.7 0.0 2.3 2 0 0 2 2 2 1 rRNA small subunit methyltransferase G FtsJ PF01728.14 KLO18675.1 - 0.001 19.0 0.0 0.0017 18.3 0.0 1.4 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_2 PF00891.13 KLO18675.1 - 0.061 12.5 0.0 0.1 11.7 0.0 1.4 1 0 0 1 1 1 0 O-methyltransferase PrmA PF06325.8 KLO18675.1 - 0.081 12.0 0.0 0.17 10.9 0.0 1.5 2 0 0 2 2 2 0 Ribosomal protein L11 methyltransferase (PrmA) Ubie_methyltran PF01209.13 KLO18675.1 - 0.11 11.6 0.0 9.7 5.2 0.0 2.2 2 0 0 2 2 2 0 ubiE/COQ5 methyltransferase family DUF938 PF06080.7 KLO18675.1 - 0.12 11.8 0.0 1.7 8.1 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF938) Methyltransf_29 PF03141.11 KLO18675.1 - 0.14 10.5 0.0 5.4 5.2 0.0 2.1 2 0 0 2 2 2 0 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_32 PF13679.1 KLO18675.1 - 0.16 11.6 0.0 0.29 10.7 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_8 PF05148.10 KLO18675.1 - 0.17 11.5 0.0 0.54 9.8 0.0 1.7 1 1 0 1 1 1 0 Hypothetical methyltransferase F-box-like PF12937.2 KLO18676.1 - 0.0052 16.4 0.1 0.02 14.6 0.1 2.1 1 0 0 1 1 1 1 F-box-like TPR_11 PF13414.1 KLO18677.1 - 5e-24 83.7 15.8 1.4e-05 24.6 0.1 8.3 8 1 1 9 9 9 6 TPR repeat TPR_2 PF07719.12 KLO18677.1 - 2.5e-18 64.4 16.2 0.0022 17.7 0.1 11.4 12 0 0 12 12 12 4 Tetratricopeptide repeat TPR_16 PF13432.1 KLO18677.1 - 1.3e-14 54.3 21.2 0.00035 21.1 0.1 9.2 11 0 0 11 11 9 4 Tetratricopeptide repeat TPR_19 PF14559.1 KLO18677.1 - 1e-13 51.3 14.1 0.00063 20.0 0.1 8.9 8 1 0 9 9 9 3 Tetratricopeptide repeat TPR_8 PF13181.1 KLO18677.1 - 2.1e-13 49.0 1.5 0.69 9.8 0.1 10.3 10 1 1 11 11 10 1 Tetratricopeptide repeat TPR_1 PF00515.23 KLO18677.1 - 1.3e-12 46.7 12.9 4.9e-05 22.7 0.1 9.8 12 0 0 12 12 12 2 Tetratricopeptide repeat TPR_14 PF13428.1 KLO18677.1 - 4e-12 45.6 17.5 0.38 11.5 0.0 12.2 8 3 5 13 13 13 1 Tetratricopeptide repeat TPR_7 PF13176.1 KLO18677.1 - 9.8e-12 43.7 9.8 1.2 9.1 0.0 9.2 9 0 0 9 9 9 3 Tetratricopeptide repeat TPR_12 PF13424.1 KLO18677.1 - 2.9e-11 43.1 17.8 0.14 12.1 0.1 9.2 8 2 3 11 11 11 4 Tetratricopeptide repeat TPR_17 PF13431.1 KLO18677.1 - 1.4e-07 31.1 2.8 2.5 8.4 0.0 8.3 9 0 0 9 9 9 1 Tetratricopeptide repeat Apc3 PF12895.2 KLO18677.1 - 2.6e-06 27.4 6.1 2.4 8.3 0.0 6.7 5 2 1 6 6 6 2 Anaphase-promoting complex, cyclosome, subunit 3 Alkyl_sulf_dimr PF14863.1 KLO18677.1 - 6.3e-05 23.2 3.1 0.068 13.4 0.0 3.7 4 0 0 4 4 4 2 Alkyl sulfatase dimerisation TPR_6 PF13174.1 KLO18677.1 - 0.00019 21.6 19.9 5 7.8 0.0 9.2 11 0 0 11 11 9 1 Tetratricopeptide repeat TPR_20 PF14561.1 KLO18677.1 - 0.0084 16.2 4.8 0.038 14.1 0.5 4.3 6 0 0 6 6 4 1 Tetratricopeptide repeat BTAD PF03704.12 KLO18677.1 - 0.025 14.8 3.0 1.5 9.1 0.0 3.3 3 0 0 3 3 3 0 Bacterial transcriptional activator domain TPR_9 PF13371.1 KLO18677.1 - 0.25 11.2 12.8 2.7 7.9 0.0 5.7 5 1 1 6 6 6 0 Tetratricopeptide repeat TPR_10 PF13374.1 KLO18677.1 - 3.7 7.5 19.6 0.79 9.7 0.1 7.1 9 0 0 9 9 8 0 Tetratricopeptide repeat MFS_1 PF07690.11 KLO18678.1 - 2.7e-38 131.6 28.8 2.7e-38 131.6 19.9 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1 PF07690.11 KLO18679.1 - 3.5e-40 137.8 27.3 3.5e-40 137.8 18.9 1.5 1 1 1 2 2 2 1 Major Facilitator Superfamily PapG_C PF03628.8 KLO18681.1 - 0.063 12.9 0.0 0.094 12.3 0.0 1.3 1 0 0 1 1 1 0 PapG chaperone-binding domain Aldo_ket_red PF00248.16 KLO18682.1 - 2.4e-38 131.5 0.0 2.7e-38 131.4 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Ctr PF04145.10 KLO18684.1 - 3.9e-28 98.3 0.0 4.9e-28 97.9 0.0 1.1 1 0 0 1 1 1 1 Ctr copper transporter family FAM176 PF14851.1 KLO18684.1 - 0.033 13.8 0.0 0.06 13.0 0.0 1.3 1 0 0 1 1 1 0 FAM176 family Ferric_reduct PF01794.14 KLO18685.1 - 1e-16 61.1 8.4 1e-16 61.1 5.8 2.1 3 0 0 3 3 3 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.7 KLO18685.1 - 1.4e-11 44.2 0.0 2.7e-11 43.2 0.0 1.5 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.7 KLO18685.1 - 2.8e-10 40.3 0.0 1.3e-09 38.1 0.0 2.1 2 0 0 2 2 2 1 Ferric reductase NAD binding domain p450 PF00067.17 KLO18687.1 - 2.8e-74 250.3 0.0 3.8e-74 249.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF3367 PF11847.3 KLO18687.1 - 0.15 9.9 0.2 0.28 9.1 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3367) p450 PF00067.17 KLO18689.1 - 2e-73 247.5 0.0 2.8e-73 247.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 PAM2 PF07145.10 KLO18689.1 - 0.38 10.3 3.7 3.2 7.4 0.0 3.2 3 0 0 3 3 3 0 Ataxin-2 C-terminal region p450 PF00067.17 KLO18690.1 - 2.9e-59 200.8 0.0 2.3e-58 197.8 0.0 2.1 1 1 0 1 1 1 1 Cytochrome P450 Alpha-amylase PF00128.19 KLO18692.1 - 2e-66 224.5 1.0 2.6e-66 224.1 0.7 1.1 1 0 0 1 1 1 1 Alpha amylase, catalytic domain DUF1966 PF09260.6 KLO18692.1 - 6.1e-13 48.6 0.1 1.6e-12 47.3 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1966) PLA2_B PF01735.13 KLO18693.1 - 3.1e-100 335.7 0.8 4.8e-100 335.0 0.5 1.3 1 0 0 1 1 1 1 Lysophospholipase catalytic domain SNF2_N PF00176.18 KLO18694.1 - 8.7e-66 221.7 0.1 1.2e-65 221.2 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 KLO18694.1 - 3.6e-13 49.1 0.0 9.2e-13 47.8 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-RING_2 PF13639.1 KLO18694.1 - 1.2e-07 31.4 6.3 3.3e-07 30.0 4.3 1.8 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 KLO18694.1 - 4.6e-07 29.3 4.4 9.9e-07 28.3 3.1 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KLO18694.1 - 9.6e-06 25.2 6.0 9.6e-06 25.2 4.2 1.9 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 KLO18694.1 - 1.1e-05 25.0 4.8 1.1e-05 25.0 3.3 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 KLO18694.1 - 5.3e-05 23.0 5.9 0.00013 21.7 4.1 1.7 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.1 KLO18694.1 - 6.3e-05 22.9 6.0 6.3e-05 22.9 4.2 1.9 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.1 KLO18694.1 - 0.00015 21.2 4.0 0.00037 20.0 2.7 1.7 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-rbx1 PF12678.2 KLO18694.1 - 0.0073 16.3 2.2 0.019 15.0 1.5 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_UBOX PF13445.1 KLO18694.1 - 0.019 14.6 2.0 0.068 12.8 1.4 2.0 1 0 0 1 1 1 0 RING-type zinc-finger DEAD_2 PF06733.10 KLO18694.1 - 0.026 13.9 0.8 0.084 12.2 0.0 2.0 2 0 0 2 2 2 0 DEAD_2 Rad50_zn_hook PF04423.9 KLO18694.1 - 0.048 13.1 1.5 6 6.4 0.1 3.3 2 0 0 2 2 2 0 Rad50 zinc hook motif DUF1886 PF09171.5 KLO18694.1 - 0.094 11.7 0.0 0.18 10.7 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1886) FYVE PF01363.16 KLO18694.1 - 0.26 11.2 5.8 1.3 9.0 4.0 2.2 1 1 0 1 1 1 0 FYVE zinc finger SAP PF02037.22 KLO18695.1 - 0.00017 20.9 0.3 0.00028 20.3 0.2 1.4 1 0 0 1 1 1 1 SAP domain HTH_10 PF04967.7 KLO18695.1 - 0.064 12.8 0.0 0.13 11.8 0.0 1.5 1 0 0 1 1 1 0 HTH DNA binding domain DUF1793 PF08760.6 KLO18697.1 - 7e-36 123.6 0.1 1.3e-35 122.7 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1793) DUF2273 PF10031.4 KLO18698.1 - 0.11 12.1 1.4 0.17 11.5 1.0 1.2 1 0 0 1 1 1 0 Small integral membrane protein (DUF2273) Syndecan PF01034.15 KLO18698.1 - 0.19 11.3 0.3 0.37 10.4 0.2 1.4 1 0 0 1 1 1 0 Syndecan domain DUF1793 PF08760.6 KLO18699.1 - 2.6e-34 118.5 0.2 5.1e-34 117.5 0.2 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1793) DUF1793 PF08760.6 KLO18701.1 - 5.5e-38 130.5 0.1 1e-37 129.6 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1793) GBA2_N PF12215.3 KLO18701.1 - 0.0063 15.7 0.2 0.012 14.8 0.1 1.4 1 0 0 1 1 1 1 beta-Glucocerebrosidase 2 N terminal Bac_rhamnosid PF05592.6 KLO18701.1 - 0.038 12.2 0.1 0.081 11.1 0.1 1.5 1 0 0 1 1 1 0 Bacterial alpha-L-rhamnosidase RRM_1 PF00076.17 KLO18703.1 - 3.2e-34 116.3 1.4 7.8e-18 63.8 0.0 2.5 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KLO18703.1 - 5.6e-29 99.9 0.3 5.3e-16 58.3 0.0 2.5 3 0 0 3 3 3 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KLO18703.1 - 7.2e-15 54.5 0.0 1.5e-08 34.3 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 KLO18703.1 - 0.014 15.1 0.0 3.1 7.6 0.0 2.4 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.6 KLO18703.1 - 0.077 12.8 0.0 1.5 8.6 0.0 2.2 2 0 0 2 2 2 0 RNA binding motif VHS PF00790.14 KLO18704.1 - 7.8e-09 35.3 0.2 1.7e-08 34.2 0.1 1.5 1 0 0 1 1 1 1 VHS domain GAT PF03127.9 KLO18704.1 - 4.5e-05 23.3 0.0 0.00015 21.6 0.0 1.9 1 1 0 1 1 1 1 GAT domain FLILHELTA PF10306.4 KLO18705.1 - 8e-10 38.6 0.0 2.2e-09 37.2 0.0 1.7 2 0 0 2 2 2 1 Hypothetical protein FLILHELTA DUF1279 PF06916.8 KLO18705.1 - 0.0069 16.6 0.0 0.012 15.8 0.0 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF1279) WD40 PF00400.27 KLO18706.1 - 3.7e-06 26.6 13.7 1.8e-05 24.4 0.2 3.9 4 0 0 4 4 4 2 WD domain, G-beta repeat UIM PF02809.15 KLO18706.1 - 0.00067 19.0 4.4 0.0028 17.0 3.0 2.2 1 0 0 1 1 1 1 Ubiquitin interaction motif F-box-like PF12937.2 KLO18706.1 - 0.00096 18.8 0.1 0.0026 17.4 0.1 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KLO18706.1 - 0.0014 18.2 0.1 0.0052 16.4 0.0 2.0 2 0 0 2 2 2 1 F-box domain P16-Arc PF04699.9 KLO18707.1 - 8.8e-53 178.4 0.1 9.8e-53 178.2 0.0 1.0 1 0 0 1 1 1 1 ARP2/3 complex 16 kDa subunit (p16-Arc) IncA PF04156.9 KLO18708.1 - 1.8 8.1 6.6 2.7 7.5 4.6 1.2 1 0 0 1 1 1 0 IncA protein PH PF00169.24 KLO18709.1 - 2e-05 24.7 0.0 2.7e-05 24.3 0.0 1.2 1 0 0 1 1 1 1 PH domain Pkinase_Tyr PF07714.12 KLO18710.1 - 6.8e-39 133.4 0.0 7.8e-39 133.2 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 KLO18710.1 - 2.6e-37 128.4 0.0 3.2e-37 128.1 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.1 KLO18710.1 - 0.00094 18.2 0.0 0.002 17.1 0.0 1.5 1 1 0 1 1 1 1 Kinase-like APH PF01636.18 KLO18710.1 - 0.029 14.0 0.0 0.046 13.4 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family SWIB PF02201.13 KLO18711.1 - 3.7e-16 58.5 0.2 8.3e-16 57.4 0.1 1.6 1 0 0 1 1 1 1 SWIB/MDM2 domain BAR PF03114.13 KLO18712.1 - 6.9e-36 123.8 2.5 1.1e-35 123.2 1.7 1.3 1 0 0 1 1 1 1 BAR domain SH3_1 PF00018.23 KLO18712.1 - 2.2e-14 52.5 0.1 4.3e-14 51.6 0.1 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 KLO18712.1 - 1.1e-13 50.5 0.1 2.2e-13 49.5 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 KLO18712.1 - 2.4e-11 42.9 0.0 4.8e-11 41.9 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain TF_Zn_Ribbon PF08271.7 KLO18712.1 - 0.67 9.3 4.3 1.3 8.4 3.0 1.4 1 0 0 1 1 1 0 TFIIB zinc-binding DUF678 PF05077.7 KLO18713.1 - 0.015 15.2 0.6 0.026 14.4 0.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF678) Sporozoite_P67 PF05642.6 KLO18714.1 - 0.26 9.0 15.5 0.31 8.8 10.8 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen SOG2 PF10428.4 KLO18714.1 - 6 5.4 16.2 7.2 5.1 11.2 1.0 1 0 0 1 1 1 0 RAM signalling pathway protein DUF4207 PF13904.1 KLO18714.1 - 8.8 5.6 7.1 11 5.3 4.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4207) Glyco_hydro_3 PF00933.16 KLO18715.1 - 8.6e-78 261.3 0.1 1.2e-77 260.8 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 KLO18715.1 - 2.6e-57 193.9 0.0 9.1e-57 192.1 0.0 2.0 2 1 0 2 2 2 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 KLO18715.1 - 5.6e-20 71.0 0.0 1.2e-19 70.0 0.0 1.6 1 0 0 1 1 1 1 Fibronectin type III-like domain Glyco_hydro_3 PF00933.16 KLO18716.1 - 0.09 11.7 0.0 0.13 11.1 0.0 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 3 N terminal domain DIOX_N PF14226.1 KLO18717.1 - 1.1e-14 54.9 0.0 2e-14 54.1 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 KLO18717.1 - 3.9e-14 52.7 0.0 1.3e-13 51.0 0.0 1.8 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily AAA_2 PF07724.9 KLO18718.1 - 7.4e-48 162.6 0.0 5.9e-45 153.2 0.0 2.4 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) ClpB_D2-small PF10431.4 KLO18718.1 - 4e-20 71.4 0.2 1.3e-19 69.8 0.1 1.9 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA PF00004.24 KLO18718.1 - 1.4e-18 67.3 0.1 3.1e-09 37.1 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 KLO18718.1 - 1.4e-16 60.4 0.0 3.6e-10 39.7 0.0 3.2 3 0 0 3 3 3 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 KLO18718.1 - 2.2e-11 44.0 6.6 8.3e-06 25.9 0.0 3.9 3 2 1 4 4 4 2 AAA ATPase domain AAA_22 PF13401.1 KLO18718.1 - 7e-09 35.9 0.0 0.0096 16.0 0.0 3.2 3 1 0 3 3 2 2 AAA domain AAA_18 PF13238.1 KLO18718.1 - 7.5e-07 29.5 0.0 0.073 13.3 0.0 3.1 2 0 0 2 2 2 2 AAA domain Sigma54_activat PF00158.21 KLO18718.1 - 8.9e-07 28.5 0.0 2.7e-05 23.7 0.0 2.4 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_17 PF13207.1 KLO18718.1 - 1.1e-06 29.4 5.9 0.013 16.2 0.1 4.0 4 1 0 4 4 3 2 AAA domain IstB_IS21 PF01695.12 KLO18718.1 - 2.7e-06 26.9 0.0 0.04 13.3 0.0 2.7 2 0 0 2 2 2 2 IstB-like ATP binding protein Arch_ATPase PF01637.13 KLO18718.1 - 3.3e-06 26.9 1.7 0.014 15.1 0.0 4.1 3 2 1 5 5 5 1 Archaeal ATPase AAA_14 PF13173.1 KLO18718.1 - 5.6e-06 26.2 0.0 0.052 13.4 0.0 2.4 2 0 0 2 2 2 2 AAA domain ABC_tran PF00005.22 KLO18718.1 - 1.6e-05 25.2 0.6 0.013 15.7 0.0 3.4 3 0 0 3 3 3 1 ABC transporter Mg_chelatase PF01078.16 KLO18718.1 - 2.8e-05 23.3 0.2 0.28 10.3 0.0 3.0 2 1 0 2 2 2 2 Magnesium chelatase, subunit ChlI RuvB_N PF05496.7 KLO18718.1 - 8.6e-05 21.6 0.4 0.44 9.5 0.0 2.9 2 1 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus AAA_19 PF13245.1 KLO18718.1 - 0.0001 21.9 1.0 0.023 14.4 0.0 3.0 3 0 0 3 3 2 1 Part of AAA domain AAA_28 PF13521.1 KLO18718.1 - 0.00012 22.0 2.0 0.21 11.5 0.0 3.8 3 1 0 3 3 3 1 AAA domain AAA_25 PF13481.1 KLO18718.1 - 0.00018 21.0 0.0 1.8 7.9 0.0 3.8 3 1 1 4 4 3 1 AAA domain AAA_24 PF13479.1 KLO18718.1 - 0.00058 19.4 0.0 0.31 10.5 0.0 2.4 2 0 0 2 2 2 1 AAA domain MobB PF03205.9 KLO18718.1 - 0.00066 19.3 0.0 0.27 10.9 0.0 2.5 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B RNA_helicase PF00910.17 KLO18718.1 - 0.00084 19.4 0.0 2.4 8.3 0.0 2.6 2 0 0 2 2 2 2 RNA helicase DUF258 PF03193.11 KLO18718.1 - 0.00094 18.4 0.0 0.9 8.7 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 ResIII PF04851.10 KLO18718.1 - 0.0028 17.5 0.0 18 5.0 0.0 3.4 3 0 0 3 3 3 0 Type III restriction enzyme, res subunit AAA_23 PF13476.1 KLO18718.1 - 0.0029 17.9 6.8 0.032 14.5 0.0 3.2 3 0 0 3 3 3 1 AAA domain NACHT PF05729.7 KLO18718.1 - 0.003 17.2 0.0 0.5 10.0 0.0 2.8 3 0 0 3 3 2 1 NACHT domain AAA_29 PF13555.1 KLO18718.1 - 0.0036 16.8 0.0 3 7.4 0.0 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain NTPase_1 PF03266.10 KLO18718.1 - 0.0048 16.6 0.2 3.9 7.1 0.0 3.8 4 0 0 4 4 3 0 NTPase Zeta_toxin PF06414.7 KLO18718.1 - 0.0063 15.6 4.6 0.11 11.5 0.0 3.5 3 0 0 3 3 3 1 Zeta toxin T2SE PF00437.15 KLO18718.1 - 0.0074 15.2 0.0 0.24 10.2 0.0 2.4 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_33 PF13671.1 KLO18718.1 - 0.0087 15.9 0.0 6.8 6.5 0.0 3.2 3 0 0 3 3 2 0 AAA domain AAA_21 PF13304.1 KLO18718.1 - 0.021 14.7 0.0 6.2 6.6 0.0 2.6 3 0 0 3 3 2 0 AAA domain SRP54 PF00448.17 KLO18718.1 - 0.022 14.2 0.0 2.4 7.5 0.0 2.5 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain DNA_pol3_delta2 PF13177.1 KLO18718.1 - 0.031 13.9 0.0 0.12 11.9 0.0 1.9 1 1 0 1 1 1 0 DNA polymerase III, delta subunit MMR_HSR1 PF01926.18 KLO18718.1 - 0.043 13.7 0.0 8.6 6.3 0.0 2.7 2 0 0 2 2 2 0 50S ribosome-binding GTPase Miro PF08477.8 KLO18718.1 - 0.056 13.9 0.0 1.2 9.6 0.0 2.5 2 0 0 2 2 2 0 Miro-like protein ATP_bind_1 PF03029.12 KLO18718.1 - 0.071 12.6 0.0 2.7 7.4 0.0 2.3 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein PduV-EutP PF10662.4 KLO18718.1 - 0.081 12.4 0.0 0.81 9.1 0.0 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Bac_DnaA PF00308.13 KLO18718.1 - 0.085 12.4 0.0 11 5.6 0.0 2.4 2 0 0 2 2 2 0 Bacterial dnaA protein IncA PF04156.9 KLO18718.1 - 0.17 11.5 7.4 0.33 10.5 5.2 1.4 1 0 0 1 1 1 0 IncA protein AAA_11 PF13086.1 KLO18718.1 - 0.21 11.1 1.8 4 6.9 0.0 3.1 3 0 0 3 3 3 0 AAA domain MSC PF09402.5 KLO18719.1 - 0.0055 15.4 0.1 0.0078 14.9 0.1 1.2 1 0 0 1 1 1 1 Man1-Src1p-C-terminal domain DUF2062 PF09835.4 KLO18719.1 - 0.013 15.1 0.8 0.024 14.2 0.1 1.8 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2062) DUF4328 PF14219.1 KLO18719.1 - 0.043 13.1 0.1 0.082 12.2 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4328) Peptidase_S66 PF02016.10 KLO18719.1 - 0.12 11.3 0.4 0.2 10.5 0.2 1.4 1 1 0 1 1 1 0 LD-carboxypeptidase Podoplanin PF05808.6 KLO18719.1 - 0.26 10.8 7.0 0.44 10.0 4.8 1.3 1 0 0 1 1 1 0 Podoplanin TMEM154 PF15102.1 KLO18720.1 - 0.062 12.9 0.2 0.11 12.1 0.1 1.4 1 0 0 1 1 1 0 TMEM154 protein family Herpes_gE PF02480.11 KLO18721.1 - 0.0055 15.0 0.7 0.0087 14.3 0.5 1.2 1 0 0 1 1 1 1 Alphaherpesvirus glycoprotein E Gram_pos_anchor PF00746.16 KLO18721.1 - 0.49 10.2 4.6 3.9 7.4 0.1 3.3 3 0 0 3 3 3 0 Gram positive anchor RAP1 PF07218.6 KLO18721.1 - 4.2 5.3 6.5 5.4 4.9 4.5 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) DUF515 PF04415.7 KLO18722.1 - 4.6 5.3 12.9 5.7 5.0 8.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF515) adh_short PF00106.20 KLO18723.1 - 2.6e-23 82.7 0.1 3.3e-23 82.4 0.1 1.0 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KLO18723.1 - 6e-13 48.8 0.1 8.7e-13 48.3 0.1 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 KLO18723.1 - 3.2e-08 33.3 0.1 5.8e-08 32.4 0.1 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short_C2 PF13561.1 KLO18723.1 - 8.2e-08 32.3 0.0 1e-07 32.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 KLO18723.1 - 8.8e-06 25.8 0.2 3.6e-05 23.8 0.0 1.8 2 0 0 2 2 2 1 NADH(P)-binding NmrA PF05368.8 KLO18723.1 - 0.00096 18.4 0.1 0.0013 17.9 0.1 1.2 1 0 0 1 1 1 1 NmrA-like family RmlD_sub_bind PF04321.12 KLO18723.1 - 0.0019 17.1 0.0 0.0025 16.7 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain DUF1776 PF08643.5 KLO18723.1 - 0.019 14.1 0.1 0.19 10.8 0.0 1.9 1 1 1 2 2 2 0 Fungal family of unknown function (DUF1776) NAD_binding_7 PF13241.1 KLO18723.1 - 0.049 13.8 0.0 0.078 13.2 0.0 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding Polysacc_synt_2 PF02719.10 KLO18723.1 - 0.063 12.1 0.0 0.069 12.0 0.0 1.1 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein YjeF_N PF03853.10 KLO18723.1 - 0.069 12.7 0.0 0.13 11.8 0.0 1.4 2 0 0 2 2 2 0 YjeF-related protein N-terminus PEMT PF04191.8 KLO18724.1 - 1.6e-30 105.3 4.1 1.6e-30 105.3 2.9 1.8 2 1 0 2 2 2 1 Phospholipid methyltransferase DUF3382 PF11862.3 KLO18724.1 - 0.061 13.2 0.0 0.13 12.2 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3382) ABC1 PF03109.11 KLO18725.1 - 3.5e-26 91.5 0.0 6.3e-26 90.6 0.0 1.5 1 0 0 1 1 1 1 ABC1 family Pkinase_Tyr PF07714.12 KLO18726.1 - 1e-45 155.8 0.0 4.5e-45 153.7 0.0 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase PF00069.20 KLO18726.1 - 1.2e-43 149.1 0.0 2e-43 148.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain RhoGEF PF00621.15 KLO18726.1 - 2.1e-07 31.0 0.1 3.5e-07 30.2 0.1 1.4 1 0 0 1 1 1 1 RhoGEF domain PH_10 PF15411.1 KLO18726.1 - 2.1e-05 24.6 0.0 7.3e-05 22.9 0.0 1.9 1 1 0 1 1 1 1 Pleckstrin homology domain APH PF01636.18 KLO18726.1 - 0.00031 20.5 0.0 0.0011 18.8 0.0 1.9 1 1 0 1 1 1 1 Phosphotransferase enzyme family CDC24 PF06395.6 KLO18726.1 - 0.0068 16.4 0.0 0.04 13.9 0.0 2.3 1 1 0 1 1 1 1 CDC24 Calponin RIO1 PF01163.17 KLO18726.1 - 0.04 13.2 0.0 0.1 11.9 0.0 1.6 1 0 0 1 1 1 0 RIO1 family Kdo PF06293.9 KLO18726.1 - 0.098 11.7 0.0 0.21 10.6 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF605 PF04652.11 KLO18727.1 - 1.1 8.5 9.4 1.6 8.0 6.5 1.2 1 0 0 1 1 1 0 Vta1 like DIOX_N PF14226.1 KLO18728.1 - 5.5e-15 55.9 0.0 1.1e-14 54.8 0.0 1.5 1 1 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 KLO18728.1 - 3.7e-13 49.6 0.0 9.7e-13 48.2 0.0 1.7 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.1 KLO18729.1 - 1.4e-14 54.6 0.0 3.3e-14 53.4 0.0 1.6 2 0 0 2 2 2 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 KLO18729.1 - 1.4e-12 47.7 0.0 2.8e-12 46.8 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily UQ_con PF00179.21 KLO18730.1 - 2e-37 127.7 0.0 2.9e-37 127.2 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 KLO18730.1 - 0.099 12.3 0.0 0.15 11.8 0.0 1.3 1 0 0 1 1 1 0 Prokaryotic E2 family B RRM_1 PF00076.17 KLO18731.1 - 3.3e-18 65.0 0.0 2e-09 36.9 0.0 3.2 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KLO18731.1 - 2.3e-16 59.5 0.1 1.6e-06 27.9 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KLO18731.1 - 1e-09 38.0 0.1 0.0022 17.7 0.0 3.2 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) HMA PF00403.21 KLO18731.1 - 0.08 13.1 0.0 5.6 7.1 0.0 2.6 2 0 0 2 2 2 0 Heavy-metal-associated domain PaaX PF07848.7 KLO18732.1 - 0.16 11.9 0.1 0.16 11.9 0.1 1.8 2 0 0 2 2 2 0 PaaX-like protein F-box-like PF12937.2 KLO18733.1 - 0.065 12.9 0.0 0.15 11.7 0.0 1.6 1 0 0 1 1 1 0 F-box-like Glyco_transf_20 PF00982.16 KLO18734.1 - 9e-153 509.1 0.0 1.2e-152 508.7 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.11 KLO18734.1 - 1.7e-22 79.4 0.0 3e-22 78.7 0.0 1.4 1 0 0 1 1 1 1 Trehalose-phosphatase DUF3849 PF12960.2 KLO18734.1 - 0.14 12.1 0.0 0.66 9.9 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3849) Metallophos PF00149.23 KLO18735.1 - 7.8e-40 136.4 0.1 1e-39 136.0 0.0 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase DUF1620 PF07774.8 KLO18736.1 - 2.2e-64 216.6 0.8 2.7e-64 216.3 0.1 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF1620) PQQ_2 PF13360.1 KLO18736.1 - 7.5e-12 45.2 3.2 2.5e-07 30.4 0.1 3.7 3 1 0 3 3 3 2 PQQ-like domain PQQ PF01011.16 KLO18736.1 - 2.5e-08 33.0 0.4 0.19 11.3 0.0 5.1 5 0 0 5 5 5 2 PQQ enzyme repeat Glyco_hydro_18 PF00704.23 KLO18737.1 - 3.7e-59 200.9 4.3 5.1e-59 200.4 3.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 DUF187 PF02638.10 KLO18737.1 - 0.038 12.8 0.0 0.057 12.2 0.0 1.3 1 0 0 1 1 1 0 Glycosyl hydrolase like GH101 Pkinase PF00069.20 KLO18738.1 - 1.3e-40 139.1 0.0 2e-40 138.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KLO18738.1 - 1.5e-13 50.4 0.0 1.7e-12 46.9 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KLO18738.1 - 2.5e-05 23.3 0.0 0.012 14.6 0.0 2.3 2 0 0 2 2 2 2 Kinase-like APH PF01636.18 KLO18738.1 - 0.076 12.7 0.1 0.18 11.4 0.0 1.7 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.9 KLO18738.1 - 0.18 10.8 0.0 0.35 9.8 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family LTD PF00932.14 KLO18739.1 - 0.1 12.7 0.0 0.12 12.3 0.0 1.2 1 0 0 1 1 1 0 Lamin Tail Domain ApoO PF09769.4 KLO18740.1 - 6.7e-34 116.8 0.3 1.9e-33 115.3 0.0 1.7 2 0 0 2 2 2 1 Apolipoprotein O UCH PF00443.24 KLO18742.1 - 9.1e-47 159.4 0.0 1.1e-46 159.1 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 KLO18742.1 - 1.1e-16 61.1 0.0 2.5e-09 36.9 0.0 2.1 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase ubiquitin PF00240.18 KLO18742.1 - 4.5e-07 29.1 0.0 1.2e-06 27.7 0.0 1.7 1 0 0 1 1 1 1 Ubiquitin family Bap31 PF05529.7 KLO18743.1 - 1.1e-52 178.3 2.2 1.2e-52 178.1 1.5 1.0 1 0 0 1 1 1 1 B-cell receptor-associated protein 31-like DUF1361 PF07099.6 KLO18743.1 - 0.047 13.5 0.0 0.13 12.0 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1361) RTA1 PF04479.8 KLO18743.1 - 0.13 11.7 2.5 0.49 9.8 1.7 1.8 1 1 0 1 1 1 0 RTA1 like protein Cortexin PF11057.3 KLO18743.1 - 0.14 11.7 0.6 1.9 8.1 0.0 2.3 2 0 0 2 2 2 0 Cortexin of kidney DUF4094 PF13334.1 KLO18743.1 - 0.21 11.9 2.9 0.79 10.1 0.1 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4094) TarH PF02203.10 KLO18743.1 - 2 8.2 7.2 0.55 10.0 2.4 1.8 2 0 0 2 2 2 0 Tar ligand binding domain homologue ASF1_hist_chap PF04729.8 KLO18744.1 - 4.1e-57 192.1 0.0 5.9e-57 191.6 0.0 1.2 1 0 0 1 1 1 1 ASF1 like histone chaperone Arrestin_N PF00339.24 KLO18745.1 - 0.0026 17.6 0.2 0.38 10.5 0.0 2.7 2 1 0 2 2 2 2 Arrestin (or S-antigen), N-terminal domain BAG PF02179.11 KLO18746.1 - 2.2e-06 27.6 0.2 7e-06 26.0 0.2 1.8 1 0 0 1 1 1 1 BAG domain IQ PF00612.22 KLO18746.1 - 0.0019 17.6 0.1 0.0076 15.8 0.1 2.0 1 0 0 1 1 1 1 IQ calmodulin-binding motif PLA2_B PF01735.13 KLO18750.1 - 2.9e-99 332.4 0.1 4.2e-99 331.9 0.1 1.2 1 0 0 1 1 1 1 Lysophospholipase catalytic domain Gp_dh_C PF02800.15 KLO18751.1 - 1.4e-72 242.2 0.1 2.1e-72 241.7 0.0 1.2 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.19 KLO18751.1 - 5.6e-59 198.4 0.6 8.2e-59 197.8 0.1 1.5 2 0 0 2 2 2 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain DapB_N PF01113.15 KLO18751.1 - 0.0074 16.1 0.9 0.037 13.9 0.0 2.4 3 0 0 3 3 3 1 Dihydrodipicolinate reductase, N-terminus RasGEF PF00617.14 KLO18752.1 - 3e-28 98.8 0.0 5.3e-28 98.0 0.0 1.4 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.15 KLO18752.1 - 3.1e-09 36.8 1.3 3.1e-09 36.8 0.9 2.2 2 1 0 2 2 2 1 RasGEF N-terminal motif AA_permease_2 PF13520.1 KLO18753.1 - 1.4e-52 178.7 40.7 1.6e-52 178.4 28.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 KLO18753.1 - 6.4e-16 57.7 31.5 8.1e-16 57.4 21.8 1.1 1 0 0 1 1 1 1 Amino acid permease PPR_3 PF13812.1 KLO18754.1 - 2e-18 65.0 9.1 0.017 15.3 0.0 9.5 9 0 0 9 9 9 5 Pentatricopeptide repeat domain PPR_2 PF13041.1 KLO18754.1 - 7.2e-13 48.2 0.0 5e-05 23.1 0.0 6.9 5 3 3 8 8 8 3 PPR repeat family PPR PF01535.15 KLO18754.1 - 3.4e-09 36.0 3.8 2.8 8.0 0.0 7.9 8 0 0 8 8 8 3 PPR repeat PPR_1 PF12854.2 KLO18754.1 - 0.00023 20.5 0.0 0.087 12.3 0.0 4.1 5 0 0 5 5 5 1 PPR repeat TPR_14 PF13428.1 KLO18754.1 - 0.14 12.8 3.2 0.79 10.5 0.0 4.0 5 0 0 5 5 5 0 Tetratricopeptide repeat CAS_CSE1 PF03378.10 KLO18755.1 - 5.3e-109 364.3 1.7 8.1e-109 363.7 0.6 1.6 2 0 0 2 2 2 1 CAS/CSE protein, C-terminus Cse1 PF08506.5 KLO18755.1 - 6.2e-96 321.1 0.0 1.4e-95 320.0 0.0 1.6 1 0 0 1 1 1 1 Cse1 IBN_N PF03810.14 KLO18755.1 - 6.7e-10 38.7 0.1 1.1e-08 34.8 0.0 3.3 3 1 0 3 3 3 1 Importin-beta N-terminal domain Xpo1 PF08389.7 KLO18755.1 - 6.7e-09 35.8 1.5 1.2e-05 25.2 0.0 4.8 6 0 0 6 6 6 1 Exportin 1-like protein HEAT_2 PF13646.1 KLO18755.1 - 0.17 12.1 4.3 1.6 9.0 0.6 3.8 3 1 0 3 3 3 0 HEAT repeats DM4_12 PF07841.8 KLO18755.1 - 0.34 11.2 0.2 3.8 7.8 0.1 2.5 1 1 1 2 2 2 0 DM4/DM12 family IQ PF00612.22 KLO18756.1 - 0.00086 18.7 0.4 0.0026 17.2 0.3 1.8 1 0 0 1 1 1 1 IQ calmodulin-binding motif Gyro_capsid PF04162.7 KLO18756.1 - 1 7.5 4.6 1.9 6.6 3.2 1.3 1 0 0 1 1 1 0 Gyrovirus capsid protein (VP1) VPS28 PF03997.7 KLO18757.1 - 3.7e-60 202.7 0.0 4.3e-60 202.5 0.0 1.0 1 0 0 1 1 1 1 VPS28 protein HSP70 PF00012.15 KLO18758.1 - 3.7e-67 226.6 9.9 3.4e-64 216.8 0.1 3.6 3 1 0 3 3 3 2 Hsp70 protein MreB_Mbl PF06723.8 KLO18758.1 - 0.00024 19.7 0.0 0.00052 18.6 0.0 1.4 1 0 0 1 1 1 1 MreB/Mbl protein DUF1686 PF07937.6 KLO18758.1 - 0.076 12.6 0.2 0.14 11.8 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1686) SR-25 PF10500.4 KLO18758.1 - 3.1 7.1 20.6 1.2 8.5 5.2 3.0 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Membr_traf_MHD PF10540.4 KLO18759.1 - 1.3e-20 73.6 0.0 4.7e-20 71.7 0.0 2.1 1 0 0 1 1 1 1 Munc13 (mammalian uncoordinated) homology domain C2 PF00168.25 KLO18759.1 - 1.2e-09 37.9 0.0 2.8e-09 36.6 0.0 1.7 1 0 0 1 1 1 1 C2 domain SOBP PF15279.1 KLO18759.1 - 2.9 8.2 10.0 0.45 10.8 0.0 2.4 2 0 0 2 2 2 0 Sine oculis-binding protein COX15-CtaA PF02628.10 KLO18760.1 - 0.049 12.5 0.1 0.078 11.8 0.0 1.3 1 0 0 1 1 1 0 Cytochrome oxidase assembly protein Phtf-FEM1B_bdg PF12129.3 KLO18760.1 - 0.054 12.8 0.0 0.11 11.9 0.0 1.5 1 0 0 1 1 1 0 Male germ-cell putative homeodomain transcription factor SET PF00856.23 KLO18762.1 - 5.1e-22 78.9 0.2 5.1e-22 78.9 0.2 3.6 2 2 0 2 2 2 1 SET domain SRI PF08236.6 KLO18762.1 - 1.1e-17 63.6 8.6 1.1e-17 63.6 6.0 2.3 1 1 1 2 2 2 1 SRI (Set2 Rpb1 interacting) domain Med26 PF08711.6 KLO18762.1 - 0.042 13.3 3.6 0.14 11.6 0.1 3.2 3 0 0 3 3 3 0 TFIIS helical bundle-like domain F-box-like PF12937.2 KLO18763.1 - 0.011 15.4 0.1 0.052 13.2 0.1 2.1 1 1 0 1 1 1 0 F-box-like RNA_pol_I_A49 PF06870.7 KLO18764.1 - 1.7e-87 293.5 3.6 2e-87 293.3 2.5 1.0 1 0 0 1 1 1 1 A49-like RNA polymerase I associated factor Polyketide_cyc2 PF10604.4 KLO18765.1 - 3.9e-08 33.5 0.2 4.4e-08 33.4 0.1 1.1 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc PF03364.15 KLO18765.1 - 3.9e-06 26.8 0.1 4.8e-06 26.5 0.1 1.1 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport GRAB PF10375.4 KLO18767.1 - 0.05 13.3 0.1 0.27 10.9 0.0 2.4 2 0 0 2 2 2 0 GRIP-related Arf-binding domain G-alpha PF00503.15 KLO18768.1 - 4.4e-117 391.0 0.0 5.4e-117 390.7 0.0 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 KLO18768.1 - 1.6e-09 37.2 0.0 6.1e-06 25.5 0.0 2.3 2 0 0 2 2 2 2 ADP-ribosylation factor family AAA_29 PF13555.1 KLO18768.1 - 0.0037 16.7 0.0 0.0073 15.8 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain Zeta_toxin PF06414.7 KLO18768.1 - 0.017 14.1 0.1 0.22 10.5 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin AAA_22 PF13401.1 KLO18768.1 - 0.12 12.4 0.1 0.38 10.8 0.0 1.8 2 1 0 2 2 2 0 AAA domain SRRM_C PF15230.1 KLO18770.1 - 1.9e-05 24.6 5.6 1.9e-05 24.6 3.9 2.1 2 1 0 2 2 2 1 Serine/arginine repetitive matrix protein C-terminus Transcrip_act PF04949.8 KLO18773.1 - 0.059 12.9 0.0 0.11 12.1 0.0 1.3 1 0 0 1 1 1 0 Transcriptional activator PI3K_p85B PF02192.11 KLO18774.1 - 0.014 14.7 1.0 0.81 9.1 0.0 2.9 3 0 0 3 3 3 0 PI3-kinase family, p85-binding domain DUF3421 PF11901.3 KLO18774.1 - 0.016 14.9 0.0 0.029 14.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3421) DUF1287 PF06940.6 KLO18777.1 - 0.061 12.7 0.8 0.39 10.1 0.2 2.3 2 1 1 3 3 3 0 Domain of unknown function (DUF1287) APH PF01636.18 KLO18778.1 - 1.3e-14 54.5 0.3 2.4e-14 53.6 0.1 1.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family Fructosamin_kin PF03881.9 KLO18778.1 - 0.032 13.2 0.0 0.13 11.1 0.0 1.9 2 0 0 2 2 2 0 Fructosamine kinase EcKinase PF02958.15 KLO18778.1 - 0.17 11.0 0.0 0.5 9.4 0.0 1.6 2 0 0 2 2 2 0 Ecdysteroid kinase Herpes_DNAp_acc PF04929.7 KLO18779.1 - 0.064 12.2 8.9 0.25 10.2 0.6 2.1 2 0 0 2 2 2 0 Herpes DNA replication accessory factor DPM2 PF07297.7 KLO18780.1 - 5.1e-25 87.5 0.9 5.8e-25 87.3 0.6 1.0 1 0 0 1 1 1 1 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) PIG-P PF08510.7 KLO18780.1 - 0.00025 20.6 0.7 0.00026 20.6 0.5 1.1 1 0 0 1 1 1 1 PIG-P ApbA PF02558.11 KLO18780.1 - 0.027 13.9 0.1 0.033 13.6 0.0 1.2 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA RF-1 PF00472.15 KLO18782.1 - 4.6e-25 87.6 2.8 4.6e-25 87.6 1.9 1.6 2 0 0 2 2 2 1 RF-1 domain Complex1_LYR_1 PF13232.1 KLO18782.1 - 0.0055 16.8 0.6 0.013 15.6 0.4 1.6 1 0 0 1 1 1 1 Complex1_LYR-like Pox_MCEL PF03291.11 KLO18784.1 - 1.1e-77 261.1 0.0 2.2e-77 260.1 0.0 1.4 1 1 0 1 1 1 1 mRNA capping enzyme Methyltransf_23 PF13489.1 KLO18784.1 - 1.9e-06 27.6 0.0 3e-06 27.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KLO18784.1 - 8.2e-06 26.2 0.0 2.2e-05 24.8 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KLO18784.1 - 1.3e-05 25.7 0.0 2.4e-05 24.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KLO18784.1 - 0.00033 21.0 0.0 0.0082 16.5 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain NNMT_PNMT_TEMT PF01234.12 KLO18784.1 - 0.00099 18.1 0.0 0.0019 17.2 0.0 1.4 1 0 0 1 1 1 1 NNMT/PNMT/TEMT family Methyltransf_31 PF13847.1 KLO18784.1 - 0.0026 17.3 0.0 0.18 11.4 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 KLO18784.1 - 0.13 12.6 0.1 0.41 11.0 0.1 1.9 1 1 0 1 1 1 0 Methyltransferase domain DUF4211 PF13926.1 KLO18785.1 - 3.8e-24 84.8 0.1 3.8e-24 84.8 0.1 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4211) PMAIP1 PF15150.1 KLO18785.1 - 0.23 11.2 3.0 6.5 6.6 0.1 3.2 2 0 0 2 2 2 0 Phorbol-12-myristate-13-acetate-induced Pkinase PF00069.20 KLO18786.1 - 9.8e-09 34.7 0.7 2e-08 33.7 0.1 1.8 2 0 0 2 2 2 1 Protein kinase domain Kdo PF06293.9 KLO18786.1 - 3.1e-05 23.1 0.1 7.6e-05 21.8 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_Tyr PF07714.12 KLO18786.1 - 0.0083 15.2 0.3 0.025 13.6 0.0 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase DUF745 PF05335.8 KLO18786.1 - 0.021 14.3 2.0 0.043 13.3 1.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF745) TPR_MLP1_2 PF07926.7 KLO18786.1 - 0.93 9.2 8.2 0.12 12.1 2.4 1.9 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein PhoD PF09423.5 KLO18787.1 - 2.5e-07 29.6 0.0 0.0077 14.8 0.0 2.3 3 0 0 3 3 3 2 PhoD-like phosphatase SPRY PF00622.23 KLO18788.1 - 6.9e-10 39.0 0.1 6.8e-08 32.6 0.0 2.7 3 0 0 3 3 3 2 SPRY domain UQ_con PF00179.21 KLO18789.1 - 9.5e-27 93.1 0.0 1.1e-26 92.9 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UEV PF05743.8 KLO18789.1 - 0.0014 18.2 0.0 0.0019 17.8 0.0 1.3 1 0 0 1 1 1 1 UEV domain BRE PF06113.7 KLO18789.1 - 0.0095 15.0 0.0 0.013 14.5 0.0 1.2 1 0 0 1 1 1 1 Brain and reproductive organ-expressed protein (BRE) RWD PF05773.17 KLO18789.1 - 0.059 13.2 0.0 0.088 12.7 0.0 1.6 1 1 0 1 1 1 0 RWD domain UQ_con PF00179.21 KLO18790.1 - 1.2e-31 109.0 0.0 1.4e-31 108.8 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 KLO18790.1 - 0.058 13.2 0.0 0.067 13.0 0.0 1.4 1 1 0 1 1 1 0 RWD domain Prok-E2_B PF14461.1 KLO18790.1 - 0.066 12.9 0.0 0.085 12.6 0.0 1.3 1 0 0 1 1 1 0 Prokaryotic E2 family B BTB PF00651.26 KLO18793.1 - 0.0015 18.5 0.0 0.0026 17.7 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain Nt_Gln_amidase PF09764.4 KLO18794.1 - 3.8e-46 156.7 0.0 4.4e-46 156.4 0.0 1.0 1 0 0 1 1 1 1 N-terminal glutamine amidase TF_Zn_Ribbon PF08271.7 KLO18795.1 - 0.0028 16.9 1.1 0.006 15.8 0.8 1.5 1 0 0 1 1 1 1 TFIIB zinc-binding Glycos_transf_1 PF00534.15 KLO18796.1 - 6.5e-20 71.2 0.0 1.1e-19 70.4 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.1 KLO18796.1 - 5.9e-09 36.1 0.0 1.1e-08 35.2 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.1 KLO18796.1 - 7.6e-05 22.9 0.0 0.00016 21.8 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 OTCace_N PF02729.16 KLO18798.1 - 3.2e-44 150.0 0.0 6.2e-44 149.1 0.0 1.5 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain OTCace PF00185.19 KLO18798.1 - 3.5e-40 137.4 0.0 4.9e-40 136.9 0.0 1.2 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain CAP_N PF01213.14 KLO18799.1 - 1.2e-76 258.0 25.6 8.1e-76 255.2 17.7 2.7 1 1 0 1 1 1 1 Adenylate cyclase associated (CAP) N terminal CAP_C PF08603.6 KLO18799.1 - 2.9e-59 198.9 4.1 4e-59 198.5 2.8 1.2 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) C terminal Mito_fiss_reg PF05308.6 KLO18799.1 - 0.016 14.5 11.5 0.49 9.7 2.3 2.5 2 0 0 2 2 2 0 Mitochondrial fission regulator TBCC PF07986.7 KLO18799.1 - 0.03 13.7 5.3 0.1 11.9 3.9 1.7 1 1 0 1 1 1 0 Tubulin binding cofactor C PAC2 PF09754.4 KLO18799.1 - 0.055 13.3 0.0 0.099 12.4 0.0 1.3 1 0 0 1 1 1 0 PAC2 family DNA_pol_phi PF04931.8 KLO18800.1 - 1.3e-57 195.2 19.7 2.6e-46 157.8 10.4 2.7 3 0 0 3 3 3 2 DNA polymerase phi Adeno_terminal PF02459.10 KLO18800.1 - 1.3 7.0 11.3 0.21 9.7 0.3 2.6 3 0 0 3 3 3 0 Adenoviral DNA terminal protein MutS_V PF00488.16 KLO18801.1 - 6.9e-85 284.1 0.1 2e-84 282.7 0.0 1.8 2 0 0 2 2 2 1 MutS domain V MutS_III PF05192.13 KLO18801.1 - 1.1e-36 126.5 2.0 1.2e-36 126.4 0.4 1.9 2 0 0 2 2 2 1 MutS domain III MutS_I PF01624.15 KLO18801.1 - 3.5e-27 94.6 0.0 8.4e-27 93.4 0.0 1.7 1 0 0 1 1 1 1 MutS domain I MutS_IV PF05190.13 KLO18801.1 - 6.6e-10 39.0 0.1 6.7e-09 35.8 0.0 2.8 3 0 0 3 3 3 1 MutS family domain IV MutS_II PF05188.12 KLO18801.1 - 1.3e-09 38.2 0.1 5.3e-09 36.2 0.0 2.2 2 0 0 2 2 2 1 MutS domain II ATP12 PF07542.6 KLO18802.1 - 2.1e-42 143.9 0.0 3.6e-42 143.1 0.0 1.4 1 0 0 1 1 1 1 ATP12 chaperone protein Glyco_hydro_cc PF11790.3 KLO18803.1 - 0.0021 17.5 0.0 0.0025 17.2 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core Linker_histone PF00538.14 KLO18805.1 - 3.3e-13 49.5 0.1 3.3e-13 49.5 0.1 1.9 2 0 0 2 2 2 1 linker histone H1 and H5 family AMP-binding PF00501.23 KLO18806.1 - 5.7e-12 44.7 0.2 1.4e-11 43.4 0.1 1.5 1 1 0 1 1 1 1 AMP-binding enzyme Linker_histone PF00538.14 KLO18807.1 - 2.4e-14 53.1 0.0 6.5e-14 51.7 0.0 1.8 1 0 0 1 1 1 1 linker histone H1 and H5 family EthD PF07110.6 KLO18807.1 - 0.066 14.1 1.1 0.27 12.1 0.0 2.5 2 1 0 2 2 2 0 EthD domain 2OG-FeII_Oxy_3 PF13640.1 KLO18808.1 - 0.00044 20.7 0.1 0.001 19.5 0.1 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.15 KLO18808.1 - 0.0021 18.3 0.1 0.0052 17.0 0.1 1.7 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily YusW PF14039.1 KLO18808.1 - 0.094 13.0 0.0 0.31 11.3 0.0 1.8 1 0 0 1 1 1 0 YusW-like protein 2OG-FeII_Oxy_3 PF13640.1 KLO18809.1 - 5.1e-08 33.3 0.6 3e-05 24.4 0.1 2.7 2 0 0 2 2 2 2 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.15 KLO18809.1 - 8.6e-06 25.9 0.1 0.0017 18.5 0.0 2.7 2 0 0 2 2 2 2 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_3 PF13640.1 KLO18810.1 - 0.00018 21.9 0.1 0.00028 21.3 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.15 KLO18810.1 - 0.00042 20.5 0.1 0.0044 17.2 0.0 2.2 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily p450 PF00067.17 KLO18812.1 - 1.1e-59 202.1 0.0 1.3e-59 201.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 FAD_binding_2 PF00890.19 KLO18815.1 - 7.7e-127 423.5 3.1 9.6e-127 423.2 2.1 1.1 1 0 0 1 1 1 1 FAD binding domain Succ_DH_flav_C PF02910.15 KLO18815.1 - 1.9e-47 160.3 0.3 3e-47 159.6 0.2 1.3 1 0 0 1 1 1 1 Fumarate reductase flavoprotein C-term Pyr_redox_2 PF07992.9 KLO18815.1 - 6.6e-08 32.6 0.1 1.4e-05 25.0 0.1 3.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 KLO18815.1 - 1e-06 28.0 0.2 0.0009 18.3 0.0 2.6 2 0 0 2 2 2 2 Thi4 family GIDA PF01134.17 KLO18815.1 - 9.3e-06 24.7 2.1 0.0048 15.8 1.8 2.3 2 0 0 2 2 2 2 Glucose inhibited division protein A DAO PF01266.19 KLO18815.1 - 5.2e-05 22.3 0.1 0.002 17.0 0.1 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 KLO18815.1 - 0.0022 17.0 0.3 0.0038 16.3 0.2 1.4 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.9 KLO18815.1 - 0.047 12.1 2.0 0.13 10.6 0.7 2.2 3 0 0 3 3 3 0 HI0933-like protein DUF600 PF04634.7 KLO18815.1 - 0.15 12.0 0.0 0.25 11.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF600 RabGAP-TBC PF00566.13 KLO18816.1 - 5.1e-32 111.0 0.2 1e-15 57.8 0.0 2.3 2 0 0 2 2 2 2 Rab-GTPase-TBC domain DUF572 PF04502.8 KLO18816.1 - 0.14 11.3 1.1 0.22 10.7 0.7 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) UCH_1 PF13423.1 KLO18817.1 - 1.1e-42 146.5 0.0 1.4e-42 146.1 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase RNase_T PF00929.19 KLO18817.1 - 3.7e-20 72.8 0.0 5.8e-20 72.2 0.0 1.3 1 0 0 1 1 1 1 Exonuclease UCH PF00443.24 KLO18817.1 - 4.9e-09 35.7 0.0 7.5e-09 35.0 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase WD40 PF00400.27 KLO18817.1 - 2.1 8.3 8.0 21 5.1 0.0 4.0 4 0 0 4 4 4 0 WD domain, G-beta repeat DUF59 PF01883.14 KLO18818.1 - 8.5e-10 38.4 0.1 1.6e-09 37.6 0.0 1.5 2 0 0 2 2 2 1 Domain of unknown function DUF59 Cullin_binding PF03556.10 KLO18819.1 - 1.2e-25 89.9 0.0 2e-25 89.1 0.0 1.3 1 0 0 1 1 1 1 Cullin binding DUF3408 PF11888.3 KLO18819.1 - 0.35 10.7 2.9 0.92 9.4 2.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3408) HTH_18 PF12833.2 KLO18820.1 - 0.014 15.4 2.0 0.033 14.2 0.1 2.1 2 0 0 2 2 2 0 Helix-turn-helix domain WD40 PF00400.27 KLO18821.1 - 4.1e-91 295.9 42.3 2.4e-13 49.3 0.2 13.7 13 0 0 13 13 13 11 WD domain, G-beta repeat NACHT PF05729.7 KLO18821.1 - 9e-09 35.1 0.0 2.2e-08 33.9 0.0 1.6 1 0 0 1 1 1 1 NACHT domain eIF2A PF08662.6 KLO18821.1 - 1.2e-07 31.6 0.0 0.013 15.2 0.0 3.9 2 2 2 4 4 4 2 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 KLO18821.1 - 7e-07 27.7 1.5 0.0028 15.8 0.2 3.9 3 2 0 4 4 4 1 Nucleoporin Nup120/160 PD40 PF07676.7 KLO18821.1 - 3e-06 26.7 3.1 11 5.7 0.0 7.6 8 0 0 8 8 8 0 WD40-like Beta Propeller Repeat AAA_16 PF13191.1 KLO18821.1 - 3.2e-06 27.2 0.0 8e-06 25.9 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 KLO18821.1 - 4.4e-05 23.6 0.0 0.00013 22.0 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA PF00004.24 KLO18821.1 - 7e-05 23.0 0.0 0.00049 20.3 0.0 2.2 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) NB-ARC PF00931.17 KLO18821.1 - 0.00013 20.8 0.0 0.00028 19.8 0.0 1.5 1 0 0 1 1 1 1 NB-ARC domain Nbas_N PF15492.1 KLO18821.1 - 0.00027 20.1 1.4 3 6.8 0.0 4.5 3 1 0 4 4 4 1 Neuroblastoma-amplified sequence, N terminal Nucleoporin_N PF08801.6 KLO18821.1 - 0.00041 19.2 1.5 0.015 14.0 0.3 3.3 2 1 1 3 3 3 1 Nup133 N terminal like Zeta_toxin PF06414.7 KLO18821.1 - 0.0011 18.0 0.0 0.0019 17.3 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin AAA_33 PF13671.1 KLO18821.1 - 0.0029 17.4 0.0 0.0077 16.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.1 KLO18821.1 - 0.0032 17.3 0.0 0.053 13.4 0.0 2.7 1 1 0 1 1 1 1 AAA domain KAP_NTPase PF07693.9 KLO18821.1 - 0.0036 16.3 0.8 0.17 10.8 0.1 2.3 1 1 0 2 2 2 1 KAP family P-loop domain FtsK_SpoIIIE PF01580.13 KLO18821.1 - 0.013 14.9 0.0 0.035 13.5 0.0 1.7 1 0 0 1 1 1 0 FtsK/SpoIIIE family Viral_helicase1 PF01443.13 KLO18821.1 - 0.014 14.8 0.0 0.026 14.0 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_17 PF13207.1 KLO18821.1 - 0.015 16.1 0.0 0.16 12.7 0.0 2.9 3 0 0 3 3 2 0 AAA domain APS_kinase PF01583.15 KLO18821.1 - 0.039 13.6 0.0 0.079 12.6 0.0 1.5 1 0 0 1 1 1 0 Adenylylsulphate kinase ABC_tran PF00005.22 KLO18821.1 - 0.04 14.2 0.0 0.09 13.0 0.0 1.5 1 0 0 1 1 1 0 ABC transporter AAA_18 PF13238.1 KLO18821.1 - 0.05 13.9 0.1 0.38 11.0 0.0 2.3 1 1 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.18 KLO18821.1 - 0.05 13.5 0.0 0.16 11.9 0.0 1.9 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_19 PF13245.1 KLO18821.1 - 0.05 13.3 0.0 0.16 11.7 0.0 1.8 1 0 0 1 1 1 0 Part of AAA domain RNA_helicase PF00910.17 KLO18821.1 - 0.051 13.7 0.0 0.22 11.6 0.0 2.2 2 0 0 2 2 1 0 RNA helicase cobW PF02492.14 KLO18821.1 - 0.098 12.0 0.0 0.31 10.4 0.0 1.8 2 0 0 2 2 1 0 CobW/HypB/UreG, nucleotide-binding domain DUF2075 PF09848.4 KLO18821.1 - 0.15 11.0 0.0 0.28 10.1 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Peptidase_C2 PF00648.16 KLO18822.1 - 2.4e-65 220.4 2.2 5.9e-44 150.2 0.2 2.2 2 0 0 2 2 2 2 Calpain family cysteine protease ZZ PF00569.12 KLO18823.1 - 3e-13 49.0 6.1 5.6e-13 48.2 4.3 1.4 1 0 0 1 1 1 1 Zinc finger, ZZ type zf-UBR PF02207.15 KLO18823.1 - 0.42 10.3 6.0 0.84 9.3 4.2 1.5 1 1 0 1 1 1 0 Putative zinc finger in N-recognin (UBR box) RdRP PF05183.7 KLO18824.1 - 8e-121 404.5 0.0 1.1e-120 404.1 0.0 1.1 1 0 0 1 1 1 1 RNA dependent RNA polymerase OTU PF02338.14 KLO18824.1 - 0.019 15.5 0.5 0.053 14.1 0.0 1.9 2 0 0 2 2 2 0 OTU-like cysteine protease G-patch PF01585.18 KLO18825.1 - 5e-05 22.9 3.7 0.00014 21.5 2.5 1.8 1 0 0 1 1 1 1 G-patch domain RRM_5 PF13893.1 KLO18825.1 - 0.16 11.8 0.0 0.73 9.7 0.0 2.2 2 1 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF3275 PF11679.3 KLO18825.1 - 1 8.9 6.6 2.1 7.9 4.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3275) MRP-L27 PF09809.4 KLO18826.1 - 2.3e-07 30.3 0.1 3.2e-07 29.9 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L27 DUF367 PF04034.8 KLO18827.1 - 7.2e-47 158.1 0.1 9.5e-47 157.7 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF367) RLI PF04068.10 KLO18827.1 - 3.4e-14 52.1 0.1 5.7e-14 51.4 0.1 1.3 1 0 0 1 1 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI Cupin_8 PF13621.1 KLO18828.1 - 9.1e-32 110.5 0.1 1.2e-31 110.0 0.1 1.1 1 0 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.7 KLO18828.1 - 5.8e-08 32.3 0.1 7.8e-06 25.3 0.0 2.2 2 0 0 2 2 2 2 Cupin superfamily protein JmjC PF02373.17 KLO18828.1 - 0.00033 20.8 0.1 0.046 13.9 0.0 2.8 3 0 0 3 3 3 1 JmjC domain, hydroxylase Cupin_2 PF07883.6 KLO18828.1 - 0.0083 15.6 0.1 0.025 14.0 0.0 1.8 2 0 0 2 2 2 1 Cupin domain DUF3535 PF12054.3 KLO18829.1 - 1.2e-91 307.6 0.1 9e-91 304.6 0.0 2.5 3 0 0 3 3 3 1 Domain of unknown function (DUF3535) SNF2_N PF00176.18 KLO18829.1 - 1.8e-76 256.7 0.0 3.8e-76 255.7 0.0 1.5 2 0 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.26 KLO18829.1 - 6.1e-13 48.4 0.0 1.4e-12 47.3 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HEAT PF02985.17 KLO18829.1 - 4.5e-11 41.8 16.4 0.74 10.0 0.0 9.8 10 0 0 10 10 10 3 HEAT repeat HEAT_EZ PF13513.1 KLO18829.1 - 0.00052 20.4 19.5 36 5.0 0.1 10.1 10 2 1 11 11 11 0 HEAT-like repeat DUF1546 PF07571.8 KLO18829.1 - 0.00073 19.5 0.1 0.068 13.2 0.0 4.0 4 0 0 4 4 4 1 Protein of unknown function (DUF1546) Vac14_Fab1_bd PF12755.2 KLO18829.1 - 0.0038 17.5 0.0 5.8 7.3 0.0 3.0 2 0 0 2 2 2 2 Vacuolar 14 Fab1-binding region DUF3385 PF11865.3 KLO18829.1 - 0.071 13.0 0.1 0.19 11.6 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3385) DUF2141 PF09912.4 KLO18830.1 - 0.00084 18.9 0.1 0.0015 18.1 0.0 1.5 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2141) DUF2407_C PF13373.1 KLO18830.1 - 0.031 14.1 0.0 0.071 13.0 0.0 1.6 1 0 0 1 1 1 0 DUF2407 C-terminal domain SKG6 PF08693.5 KLO18830.1 - 0.059 12.6 0.2 0.22 10.8 0.2 2.0 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Shisa PF13908.1 KLO18830.1 - 0.29 11.3 4.2 5.9 7.0 0.0 2.5 2 0 0 2 2 2 0 Wnt and FGF inhibitory regulator DUF1370 PF07114.6 KLO18830.1 - 0.39 9.8 4.5 0.067 12.3 0.6 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1370) DUF2893 PF11459.3 KLO18832.1 - 0.12 12.1 0.2 2 8.2 0.0 2.3 2 0 0 2 2 2 0 Protein of unknwon function (DUF2893) Oligomerisation PF02410.10 KLO18833.1 - 0.00055 19.9 0.0 0.00086 19.2 0.0 1.3 1 0 0 1 1 1 1 Oligomerisation domain SHR3_chaperone PF08229.6 KLO18834.1 - 7.7e-26 90.2 0.0 1.3e-25 89.4 0.0 1.3 1 1 0 1 1 1 1 ER membrane protein SH3 DUF4094 PF13334.1 KLO18834.1 - 0.0098 16.2 0.8 0.21 11.9 0.1 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF4094) EI24 PF07264.6 KLO18835.1 - 1.2e-31 109.9 12.7 1.8e-31 109.2 8.8 1.3 1 0 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) tRNA_int_endo PF01974.12 KLO18836.1 - 1.2e-14 53.9 0.0 2.3e-14 52.9 0.0 1.4 1 0 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain RAP1 PF07218.6 KLO18836.1 - 0.034 12.2 2.5 0.041 11.9 1.7 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Lipase_GDSL_2 PF13472.1 KLO18837.1 - 1e-27 97.4 0.0 1.2e-27 97.1 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 KLO18837.1 - 1.5e-19 70.8 0.0 1.9e-19 70.4 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Rhodanese PF00581.15 KLO18838.1 - 1.1e-12 48.2 0.0 2.4e-12 47.1 0.0 1.6 1 0 0 1 1 1 1 Rhodanese-like domain Helicase_C PF00271.26 KLO18839.1 - 4.4e-14 52.1 0.0 1.1e-13 50.7 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 KLO18839.1 - 1.9e-12 47.0 0.0 3.1e-11 43.0 0.0 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase 2Fe-2S_thioredx PF01257.14 KLO18840.1 - 1.4e-58 196.6 0.0 1.7e-58 196.3 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin-like [2Fe-2S] ferredoxin DUF3786 PF12654.2 KLO18840.1 - 0.07 12.3 0.0 0.11 11.7 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3786) Bestrophin PF01062.16 KLO18841.1 - 3.8e-49 167.2 0.0 2.4e-26 92.3 0.0 2.1 2 0 0 2 2 2 2 Bestrophin, RFP-TM, chloride channel GCIP PF13324.1 KLO18842.1 - 1.2e-13 50.9 0.2 1.7e-13 50.4 0.1 1.2 1 0 0 1 1 1 1 Grap2 and cyclin-D-interacting DUF1227 PF06777.6 KLO18845.1 - 5.1e-61 204.6 0.5 1.1e-60 203.6 0.3 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1227) Helicase_C_2 PF13307.1 KLO18845.1 - 3.5e-45 153.9 0.0 7.3e-45 152.9 0.0 1.6 1 0 0 1 1 1 1 Helicase C-terminal domain DEAD_2 PF06733.10 KLO18845.1 - 5.9e-45 152.7 0.0 1e-44 151.9 0.0 1.4 1 0 0 1 1 1 1 DEAD_2 DEAD PF00270.24 KLO18845.1 - 0.0021 17.5 0.8 0.16 11.4 0.0 2.7 3 0 0 3 3 3 1 DEAD/DEAH box helicase ResIII PF04851.10 KLO18845.1 - 0.0049 16.7 0.1 0.14 11.9 0.0 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit SNF2_N PF00176.18 KLO18845.1 - 0.01 14.6 0.0 0.9 8.2 0.0 2.2 2 0 0 2 2 2 0 SNF2 family N-terminal domain FBA_3 PF08268.7 KLO18845.1 - 0.12 12.1 0.2 0.36 10.5 0.1 1.8 2 0 0 2 2 2 0 F-box associated domain AAA_22 PF13401.1 KLO18845.1 - 0.15 12.2 0.1 6.6 6.8 0.0 2.7 2 0 0 2 2 2 0 AAA domain E1_dh PF00676.15 KLO18846.1 - 1e-115 385.5 0.0 1.2e-115 385.3 0.0 1.0 1 0 0 1 1 1 1 Dehydrogenase E1 component DXP_synthase_N PF13292.1 KLO18846.1 - 2.6e-05 23.3 0.0 4.7e-05 22.4 0.0 1.4 1 1 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase TPP_enzyme_C PF02775.16 KLO18846.1 - 0.0028 17.2 2.2 0.006 16.1 0.4 2.0 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain EIIBC-GUT_C PF07663.6 KLO18846.1 - 0.11 12.6 0.2 0.25 11.4 0.1 1.5 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II C-terminus DUF1713 PF08213.6 KLO18847.1 - 5.3e-07 29.1 21.0 7.5e-07 28.6 14.5 1.2 1 0 0 1 1 1 1 Mitochondrial domain of unknown function (DUF1713) Ribosomal_L21p PF00829.16 KLO18847.1 - 0.03 14.4 0.4 0.05 13.7 0.2 1.3 1 0 0 1 1 1 0 Ribosomal prokaryotic L21 protein RVP PF00077.15 KLO18848.1 - 0.047 13.6 0.0 0.14 12.1 0.0 1.8 2 0 0 2 2 2 0 Retroviral aspartyl protease DUF3437 PF11919.3 KLO18849.1 - 3.8e-22 77.8 0.3 1.9e-21 75.5 0.0 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF3437) HEAT_2 PF13646.1 KLO18849.1 - 0.0013 18.9 0.0 1.8 8.8 0.0 2.9 2 0 0 2 2 2 2 HEAT repeats HEAT PF02985.17 KLO18849.1 - 0.025 14.6 0.0 14 6.0 0.0 3.3 2 0 0 2 2 2 0 HEAT repeat UCH PF00443.24 KLO18849.1 - 0.035 13.2 1.7 1.8 7.6 0.3 2.7 2 0 0 2 2 2 0 Ubiquitin carboxyl-terminal hydrolase HD_assoc PF13286.1 KLO18849.1 - 0.045 14.0 0.0 0.24 11.7 0.0 2.2 1 0 0 1 1 1 0 Phosphohydrolase-associated domain Osteoregulin PF07175.6 KLO18850.1 - 0.13 12.0 0.2 0.23 11.2 0.1 1.3 1 0 0 1 1 1 0 Osteoregulin TPR_2 PF07719.12 KLO18855.1 - 0.56 10.2 3.5 26 5.0 0.0 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat Cellulase PF00150.13 KLO18856.1 - 2.8e-15 56.2 0.7 2.8e-15 56.2 0.5 2.3 2 1 0 2 2 2 1 Cellulase (glycosyl hydrolase family 5) Cellulase-like PF12876.2 KLO18856.1 - 2.1e-05 24.8 0.0 4.9e-05 23.6 0.0 1.6 1 0 0 1 1 1 1 Sugar-binding cellulase-like DUF4038 PF13204.1 KLO18856.1 - 0.0003 20.2 0.0 0.014 14.7 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF4038) Glyco_hydro_42 PF02449.10 KLO18856.1 - 0.11 11.5 3.7 0.62 9.1 0.1 2.4 3 0 0 3 3 3 0 Beta-galactosidase Glyco_hydro_2_C PF02836.12 KLO18856.1 - 0.12 11.2 0.1 0.24 10.2 0.1 1.4 1 0 0 1 1 1 0 Glycosyl hydrolases family 2, TIM barrel domain Chalcone PF02431.10 KLO18860.1 - 0.13 11.6 0.0 0.17 11.2 0.0 1.1 1 0 0 1 1 1 0 Chalcone-flavanone isomerase PUF PF00806.14 KLO18862.1 - 3.2e-19 67.2 0.0 9.4e-05 21.6 0.0 6.2 6 0 0 6 6 6 5 Pumilio-family RNA binding repeat COG6 PF06419.6 KLO18863.1 - 3.7e-146 487.8 0.0 5.2e-146 487.3 0.0 1.1 1 0 0 1 1 1 1 Conserved oligomeric complex COG6 Phage_connect_1 PF05135.8 KLO18863.1 - 0.02 15.0 0.2 5.1 7.3 0.0 3.5 3 0 0 3 3 3 0 Phage gp6-like head-tail connector protein IncA PF04156.9 KLO18863.1 - 0.025 14.1 0.9 0.08 12.5 0.6 1.8 1 0 0 1 1 1 0 IncA protein Laminin_II PF06009.7 KLO18863.1 - 0.028 14.1 1.3 0.083 12.6 0.1 2.4 3 0 0 3 3 3 0 Laminin Domain II NPV_P10 PF05531.7 KLO18863.1 - 0.043 14.0 0.3 0.79 10.0 0.0 3.0 3 0 0 3 3 3 0 Nucleopolyhedrovirus P10 protein Nup54 PF13874.1 KLO18863.1 - 0.047 13.3 1.2 0.15 11.7 0.1 2.4 2 1 0 2 2 2 0 Nucleoporin complex subunit 54 MscS_porin PF12795.2 KLO18863.1 - 0.23 10.7 7.5 0.068 12.4 1.9 2.5 2 0 0 2 2 2 0 Mechanosensitive ion channel porin domain Aldolase_II PF00596.16 KLO18864.1 - 1.6e-43 148.4 0.0 2.1e-43 148.0 0.0 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain CdhC PF03598.10 KLO18866.1 - 0.12 10.8 0.0 0.15 10.5 0.0 1.1 1 0 0 1 1 1 0 CO dehydrogenase/acetyl-CoA synthase complex beta subunit MIF PF01187.13 KLO18868.1 - 4.8e-13 49.1 0.0 5.5e-13 48.9 0.0 1.0 1 0 0 1 1 1 1 Macrophage migration inhibitory factor (MIF) Tautomerase PF01361.16 KLO18868.1 - 0.032 13.8 0.0 2 8.1 0.0 2.1 2 0 0 2 2 2 0 Tautomerase enzyme MIF PF01187.13 KLO18869.1 - 1.3e-16 60.6 0.0 1.5e-16 60.5 0.0 1.0 1 0 0 1 1 1 1 Macrophage migration inhibitory factor (MIF) MIF PF01187.13 KLO18870.1 - 1.8e-21 76.3 0.0 2.1e-21 76.1 0.0 1.0 1 0 0 1 1 1 1 Macrophage migration inhibitory factor (MIF) Tautomerase PF01361.16 KLO18870.1 - 8.8e-05 22.0 0.1 0.3 10.7 0.0 2.1 2 0 0 2 2 2 2 Tautomerase enzyme DctQ PF04290.7 KLO18871.1 - 6.9 6.4 14.3 2.1 8.1 1.3 3.4 2 1 1 3 3 3 0 Tripartite ATP-independent periplasmic transporters, DctQ component DSPc PF00782.15 KLO18872.1 - 5.1e-30 103.7 0.0 6.1e-30 103.5 0.0 1.1 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 KLO18872.1 - 1.5e-05 24.4 0.1 1.9e-05 24.1 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Init_tRNA_PT PF04179.7 KLO18872.1 - 0.0032 16.3 0.0 0.0036 16.2 0.0 1.0 1 0 0 1 1 1 1 Initiator tRNA phosphoribosyl transferase CDKN3 PF05706.7 KLO18872.1 - 0.057 12.8 0.1 0.082 12.3 0.1 1.2 1 0 0 1 1 1 0 Cyclin-dependent kinase inhibitor 3 (CDKN3) Pro-kuma_activ PF09286.6 KLO18874.1 - 3.3e-37 127.7 0.0 6.4e-37 126.7 0.0 1.5 2 0 0 2 2 2 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.17 KLO18874.1 - 4.5e-06 26.0 0.0 7e-06 25.3 0.0 1.3 1 0 0 1 1 1 1 Subtilase family eRF1_2 PF03464.10 KLO18875.1 - 5.8e-46 156.1 0.2 1.3e-45 154.9 0.0 1.7 2 0 0 2 2 2 1 eRF1 domain 2 eRF1_3 PF03465.10 KLO18875.1 - 8.1e-39 132.3 0.1 1.6e-38 131.4 0.1 1.5 1 0 0 1 1 1 1 eRF1 domain 3 eRF1_1 PF03463.10 KLO18875.1 - 5.9e-25 87.3 0.0 1.2e-24 86.3 0.0 1.5 1 0 0 1 1 1 1 eRF1 domain 1 MFS_1 PF07690.11 KLO18876.1 - 6.8e-39 133.5 59.6 6.8e-39 133.5 41.3 2.4 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 KLO18876.1 - 2e-16 59.3 11.2 2e-16 59.3 7.8 1.5 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Plus-3 PF03126.13 KLO18877.1 - 9.4e-19 67.4 0.0 2.7e-18 65.9 0.0 1.8 1 0 0 1 1 1 1 Plus-3 domain RNA_pol_Rpc34 PF05158.7 KLO18878.1 - 1.1e-76 258.1 4.4 4.9e-76 256.0 3.1 1.8 1 1 0 1 1 1 1 RNA polymerase Rpc34 subunit eIF3_subunit PF08597.5 KLO18878.1 - 0.062 12.8 18.0 0.11 11.9 12.5 1.4 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit Dsh_C PF12316.3 KLO18878.1 - 0.13 12.4 4.3 0.2 11.7 3.0 1.2 1 0 0 1 1 1 0 Segment polarity protein dishevelled (Dsh) C terminal Rrf2 PF02082.15 KLO18878.1 - 0.14 12.3 0.1 0.41 10.7 0.1 1.7 1 0 0 1 1 1 0 Transcriptional regulator RPA_C PF08784.6 KLO18878.1 - 0.26 11.7 0.1 0.26 11.7 0.1 2.2 2 0 0 2 2 2 0 Replication protein A C terminal CobT PF06213.7 KLO18878.1 - 0.61 9.1 13.5 1.1 8.3 9.4 1.3 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Presenilin PF01080.12 KLO18878.1 - 1.2 7.8 3.2 1.9 7.2 2.2 1.3 1 0 0 1 1 1 0 Presenilin RR_TM4-6 PF06459.7 KLO18878.1 - 2.3 8.0 12.1 3.8 7.3 8.4 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF1510 PF07423.6 KLO18878.1 - 5.7 6.2 18.8 9.5 5.5 13.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) BPL_N PF09825.4 KLO18879.1 - 2.2e-98 329.4 0.0 2.7e-98 329.1 0.0 1.1 1 0 0 1 1 1 1 Biotin-protein ligase, N terminal BPL_LplA_LipB PF03099.14 KLO18879.1 - 1e-20 74.0 0.0 4e-20 72.0 0.0 1.9 2 0 0 2 2 2 1 Biotin/lipoate A/B protein ligase family BPL_C PF02237.12 KLO18879.1 - 0.0048 16.5 0.0 0.017 14.7 0.0 2.0 1 0 0 1 1 1 1 Biotin protein ligase C terminal domain GATase_3 PF07685.9 KLO18879.1 - 0.082 12.5 0.0 0.14 11.7 0.0 1.3 1 0 0 1 1 1 0 CobB/CobQ-like glutamine amidotransferase domain AAA_11 PF13086.1 KLO18880.1 - 3.1e-60 203.7 0.1 6.4e-60 202.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_12 PF13087.1 KLO18880.1 - 1.5e-58 197.5 0.0 2.7e-58 196.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 KLO18880.1 - 3.3e-11 42.7 0.1 1.5e-10 40.6 0.1 2.0 2 0 0 2 2 2 1 Part of AAA domain Viral_helicase1 PF01443.13 KLO18880.1 - 9e-11 41.7 0.5 0.012 15.1 0.0 3.8 4 0 0 4 4 4 3 Viral (Superfamily 1) RNA helicase AAA_30 PF13604.1 KLO18880.1 - 5.2e-09 35.9 0.0 3.6e-06 26.6 0.0 3.0 2 0 0 2 2 2 2 AAA domain DUF2075 PF09848.4 KLO18880.1 - 5.3e-06 25.6 0.3 0.12 11.3 0.0 3.3 3 1 0 3 3 3 2 Uncharacterized conserved protein (DUF2075) ResIII PF04851.10 KLO18880.1 - 0.00012 21.9 0.1 0.0029 17.4 0.1 2.4 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_16 PF13191.1 KLO18880.1 - 0.00024 21.1 0.0 0.00067 19.6 0.0 1.9 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 KLO18880.1 - 0.00088 19.4 0.0 0.045 13.8 0.0 2.6 2 0 0 2 2 2 1 AAA domain UvrD_C_2 PF13538.1 KLO18880.1 - 0.0017 18.4 0.0 0.014 15.5 0.0 2.3 2 0 0 2 2 2 1 UvrD-like helicase C-terminal domain AAA_25 PF13481.1 KLO18880.1 - 0.0021 17.5 0.1 0.01 15.2 0.0 2.1 1 1 0 1 1 1 1 AAA domain PhoH PF02562.11 KLO18880.1 - 0.0064 15.7 0.0 0.67 9.1 0.0 2.5 2 0 0 2 2 2 1 PhoH-like protein UvrD_C PF13361.1 KLO18880.1 - 0.01 15.3 0.8 0.8 9.0 0.1 2.7 2 1 1 3 3 3 0 UvrD-like helicase C-terminal domain AAA PF00004.24 KLO18880.1 - 0.019 15.1 1.9 0.2 11.8 0.2 3.1 2 1 1 3 3 3 0 ATPase family associated with various cellular activities (AAA) UvrD-helicase PF00580.16 KLO18880.1 - 0.034 13.4 0.1 0.16 11.2 0.0 2.1 1 1 0 1 1 1 0 UvrD/REP helicase N-terminal domain AAA_17 PF13207.1 KLO18880.1 - 0.06 14.1 0.7 0.82 10.5 0.2 2.8 2 1 0 2 2 2 0 AAA domain DNA_pol_B_thumb PF14791.1 KLO18882.1 - 3.7e-20 71.3 0.0 8.6e-20 70.2 0.0 1.7 1 0 0 1 1 1 1 DNA polymerase beta thumb DNA_pol_B_palm PF14792.1 KLO18882.1 - 7.3e-15 54.9 0.0 1.3e-14 54.2 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase beta palm HHH_8 PF14716.1 KLO18882.1 - 1.2e-13 50.9 0.0 3e-12 46.5 0.0 2.5 2 0 0 2 2 2 1 Helix-hairpin-helix domain DNA_pol_lambd_f PF10391.4 KLO18882.1 - 6.1e-08 32.0 0.0 1.5e-07 30.8 0.0 1.6 1 0 0 1 1 1 1 Fingers domain of DNA polymerase lambda HHH_5 PF14520.1 KLO18882.1 - 0.00016 21.7 0.4 0.0024 18.0 0.0 3.0 3 1 0 3 3 3 1 Helix-hairpin-helix domain Cdd1 PF11731.3 KLO18882.1 - 0.0032 17.3 0.0 0.017 15.0 0.0 2.1 1 1 0 1 1 1 1 Pathogenicity locus HHH PF00633.18 KLO18882.1 - 0.021 14.5 0.0 0.052 13.2 0.0 1.7 1 0 0 1 1 1 0 Helix-hairpin-helix motif IMS_HHH PF11798.3 KLO18882.1 - 0.098 12.7 0.0 2.5 8.3 0.0 2.6 2 0 0 2 2 2 0 IMS family HHH motif InaF-motif PF15018.1 KLO18884.1 - 2.7e-06 26.7 9.7 0.0077 15.6 0.1 4.0 3 0 0 3 3 3 2 TRP-interacting helix Peptidase_M16_C PF05193.16 KLO18884.1 - 0.037 13.6 0.2 3.9 7.1 0.0 2.3 2 0 0 2 2 2 0 Peptidase M16 inactive domain Helitron_like_N PF14214.1 KLO18886.1 - 1e-05 25.3 0.0 1.4e-05 24.9 0.0 1.2 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus LRR_4 PF12799.2 KLO18888.1 - 0.0048 16.4 0.1 0.56 9.8 0.0 3.6 4 0 0 4 4 4 1 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KLO18888.1 - 0.038 13.7 0.2 1.8 8.4 0.0 3.1 3 0 0 3 3 3 0 Leucine rich repeat F-box-like PF12937.2 KLO18888.1 - 0.053 13.2 0.0 0.27 10.9 0.0 2.2 2 1 0 2 2 2 0 F-box-like F-box PF00646.28 KLO18893.1 - 0.084 12.5 0.0 0.19 11.4 0.0 1.6 1 0 0 1 1 1 0 F-box domain zf-B_box PF00643.19 KLO18894.1 - 0.41 10.5 3.3 0.78 9.6 2.3 1.5 1 0 0 1 1 1 0 B-box zinc finger ox_reductase_C PF08635.5 KLO18898.1 - 9.3e-56 187.2 0.1 1.4e-55 186.5 0.0 1.3 1 0 0 1 1 1 1 Putative oxidoreductase C terminal GFO_IDH_MocA PF01408.17 KLO18898.1 - 2e-11 44.4 0.0 3.6e-11 43.6 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold HEAT_2 PF13646.1 KLO18899.1 - 3.8e-12 46.3 15.4 0.0026 18.0 0.0 8.5 7 2 1 8 8 8 5 HEAT repeats HEAT PF02985.17 KLO18899.1 - 9.6e-05 22.1 21.2 0.21 11.7 0.0 9.6 11 0 0 11 11 11 3 HEAT repeat HEAT_EZ PF13513.1 KLO18899.1 - 0.00011 22.6 18.3 0.011 16.2 0.2 8.1 7 1 1 8 8 8 2 HEAT-like repeat Arm PF00514.18 KLO18899.1 - 0.0015 18.2 1.6 0.28 11.0 0.3 4.3 3 1 1 4 4 4 1 Armadillo/beta-catenin-like repeat Sld5 PF05916.6 KLO18901.1 - 0.0066 16.7 0.0 0.011 16.0 0.0 1.4 1 0 0 1 1 1 1 GINS complex protein Zn_clus PF00172.13 KLO18902.1 - 2.3e-05 24.1 9.3 4.2e-05 23.3 6.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PAT1 PF09770.4 KLO18902.1 - 0.23 9.6 7.0 0.26 9.4 4.8 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Glyco_hydro_1 PF00232.13 KLO18904.1 - 1.2e-159 531.3 0.5 1.4e-159 531.1 0.4 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 1 Glyco_hydro_cc PF11790.3 KLO18904.1 - 0.054 12.9 0.0 0.12 11.7 0.0 1.6 1 0 0 1 1 1 0 Glycosyl hydrolase catalytic core GFO_IDH_MocA PF01408.17 KLO18905.1 - 1.4e-14 54.6 0.1 2.9e-14 53.6 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 KLO18905.1 - 2.9e-05 23.8 0.0 5e-05 23.0 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain Peroxin-3 PF04882.7 KLO18906.1 - 2e-93 313.4 0.0 2.5e-93 313.1 0.0 1.1 1 0 0 1 1 1 1 Peroxin-3 GrpE PF01025.14 KLO18906.1 - 0.071 12.6 0.2 0.14 11.6 0.1 1.4 1 0 0 1 1 1 0 GrpE PH_6 PF15406.1 KLO18906.1 - 0.13 12.3 0.2 0.24 11.4 0.2 1.4 1 0 0 1 1 1 0 Pleckstrin homology domain AAA_5 PF07728.9 KLO18907.1 - 9.2e-62 206.8 0.0 3.4e-29 101.3 0.0 3.6 3 0 0 3 3 3 3 AAA domain (dynein-related subfamily) vWA-TerF-like PF10138.4 KLO18907.1 - 0.00019 21.2 0.1 0.0013 18.5 0.0 2.1 2 0 0 2 2 2 1 vWA found in TerF C terminus VWA_2 PF13519.1 KLO18907.1 - 0.00021 21.4 0.0 0.0004 20.5 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain GNVR PF13807.1 KLO18907.1 - 0.0015 18.2 0.0 0.004 16.8 0.0 1.7 1 0 0 1 1 1 1 G-rich domain on putative tyrosine kinase AAA_22 PF13401.1 KLO18907.1 - 0.051 13.7 0.0 0.19 11.8 0.0 2.0 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.1 KLO18907.1 - 0.42 10.5 3.7 7.3 6.5 0.0 4.0 4 1 1 5 5 5 0 AAA ATPase domain Sds3 PF08598.6 KLO18908.1 - 4.5e-15 55.7 0.1 4.5e-15 55.7 0.0 2.1 2 0 0 2 2 2 1 Sds3-like Far-17a_AIG1 PF04750.9 KLO18909.1 - 1.6e-29 102.5 3.3 2e-29 102.2 2.3 1.1 1 0 0 1 1 1 1 FAR-17a/AIG1-like protein DUF21 PF01595.15 KLO18909.1 - 0.16 11.2 3.4 0.073 12.3 0.4 1.8 2 0 0 2 2 2 0 Domain of unknown function DUF21 Vps26 PF03643.10 KLO18910.1 - 3.1e-129 429.5 3.6 3.6e-129 429.4 2.5 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 26 Gln-synt_N PF03951.14 KLO18910.1 - 0.058 12.9 0.0 0.12 12.0 0.0 1.5 1 0 0 1 1 1 0 Glutamine synthetase, beta-Grasp domain p450 PF00067.17 KLO18912.1 - 1.5e-58 198.4 0.0 2.3e-57 194.5 0.0 2.0 1 1 0 1 1 1 1 Cytochrome P450 DUF2254 PF10011.4 KLO18912.1 - 0.075 11.4 0.0 0.12 10.7 0.0 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2254) DUF3357 PF11837.3 KLO18913.1 - 0.011 15.6 0.1 2.2 8.1 0.0 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF3357) EphA2_TM PF14575.1 KLO18913.1 - 0.047 14.0 0.3 0.24 11.8 0.0 2.3 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain DUF1761 PF08570.5 KLO18913.1 - 1.8 8.6 9.3 0.052 13.5 0.7 2.6 3 1 1 4 4 4 0 Protein of unknown function (DUF1761) Phageshock_PspD PF09584.5 KLO18915.1 - 0.094 12.4 0.0 2.2 8.0 0.0 2.3 2 0 0 2 2 2 0 Phage shock protein PspD (Phageshock_PspD) DUF2838 PF10998.3 KLO18916.1 - 0.017 15.0 0.3 0.054 13.3 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2838) Zn_clus PF00172.13 KLO18917.1 - 0.00023 21.0 8.0 0.00033 20.4 5.5 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PLA2_B PF01735.13 KLO18918.1 - 1e-81 274.6 13.2 1.9e-77 260.4 9.2 3.2 1 1 0 1 1 1 1 Lysophospholipase catalytic domain AMP-binding PF00501.23 KLO18919.1 - 1.8e-31 108.9 0.0 1.1e-30 106.3 0.0 1.9 1 1 0 1 1 1 1 AMP-binding enzyme Iron_traffic PF04362.9 KLO18920.1 - 0.014 14.8 0.0 0.024 14.0 0.0 1.3 1 0 0 1 1 1 0 Bacterial Fe(2+) trafficking Ribosomal_L7Ae PF01248.21 KLO18921.1 - 1.7e-21 75.5 0.3 3.5e-21 74.5 0.2 1.5 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Methyltransf_16 PF10294.4 KLO18922.1 - 4.7e-21 74.9 0.0 6e-21 74.6 0.0 1.1 1 0 0 1 1 1 1 Putative methyltransferase GidB PF02527.10 KLO18922.1 - 0.00065 18.8 0.0 0.00091 18.4 0.0 1.2 1 0 0 1 1 1 1 rRNA small subunit methyltransferase G Methyltransf_18 PF12847.2 KLO18922.1 - 0.0016 18.9 0.0 0.0029 18.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 KLO18922.1 - 0.075 12.1 0.0 0.11 11.5 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) zf-RING_3 PF14369.1 KLO18923.1 - 0.12 12.4 0.0 0.23 11.4 0.0 1.5 1 0 0 1 1 1 0 zinc-finger Rhomboid_SP PF12595.3 KLO18923.1 - 0.88 9.1 7.1 1.4 8.4 4.9 1.5 1 1 0 1 1 1 0 Rhomboid serine protease PI-PLC-X PF00388.14 KLO18924.1 - 8.8e-51 171.1 0.0 1.6e-50 170.2 0.0 1.5 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.14 KLO18924.1 - 2.6e-39 133.8 0.3 5.7e-39 132.7 0.2 1.6 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain C2 PF00168.25 KLO18924.1 - 1.1e-11 44.4 0.0 2.8e-11 43.1 0.0 1.8 1 0 0 1 1 1 1 C2 domain EF-hand_like PF09279.6 KLO18924.1 - 1.8e-05 24.6 2.5 0.016 15.2 0.0 3.3 2 1 1 3 3 3 2 Phosphoinositide-specific phospholipase C, efhand-like EF-hand_7 PF13499.1 KLO18924.1 - 9.4e-05 22.4 5.7 0.0033 17.5 0.5 2.5 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_1 PF00036.27 KLO18924.1 - 0.0021 17.2 1.2 0.0099 15.1 0.1 2.6 2 0 0 2 2 2 1 EF hand EF-hand_6 PF13405.1 KLO18924.1 - 0.11 12.4 1.7 0.61 10.1 0.0 3.1 4 0 0 4 4 4 0 EF-hand domain EF-hand_8 PF13833.1 KLO18924.1 - 0.18 11.4 1.2 4.9 6.8 0.7 3.3 3 1 0 3 3 3 0 EF-hand domain pair PLA2_B PF01735.13 KLO18926.1 - 1.6e-72 244.2 12.5 8.9e-70 235.2 8.6 3.1 1 1 0 1 1 1 1 Lysophospholipase catalytic domain Spt5-NGN PF03439.8 KLO18930.1 - 1.3e-23 82.4 0.0 2.6e-23 81.5 0.0 1.5 1 0 0 1 1 1 1 Early transcription elongation factor of RNA pol II, NGN section KOW PF00467.24 KLO18930.1 - 1.1e-09 37.5 14.1 0.00038 20.0 0.1 6.5 7 0 0 7 7 7 3 KOW motif Spt5_N PF11942.3 KLO18930.1 - 1.4e-09 38.4 11.8 1.4e-09 38.4 8.1 3.5 2 1 0 2 2 2 1 Spt5 transcription elongation factor, acidic N-terminal CTD PF12815.2 KLO18930.1 - 5.2e-09 36.5 43.0 5.7e-06 26.7 27.3 3.4 1 1 1 2 2 2 2 Spt5 C-terminal nonapeptide repeat binding Spt4 Cellulase PF00150.13 KLO18932.1 - 1.7e-08 34.0 0.0 5.3e-08 32.3 0.0 1.7 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Cellulase PF00150.13 KLO18933.1 - 6.4e-09 35.4 0.2 1.2e-07 31.2 0.2 2.1 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Env-gp36 PF09590.5 KLO18933.1 - 0.094 10.9 0.0 0.13 10.4 0.0 1.1 1 0 0 1 1 1 0 Lentivirus surface glycoprotein Mg_chelatase PF01078.16 KLO18934.1 - 0.04 13.0 0.0 0.069 12.3 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_16 PF13191.1 KLO18934.1 - 0.049 13.6 0.0 0.17 11.8 0.0 1.9 1 0 0 1 1 1 0 AAA ATPase domain MDM31_MDM32 PF08118.6 KLO18935.1 - 0.067 11.6 0.0 0.094 11.1 0.0 1.1 1 0 0 1 1 1 0 Yeast mitochondrial distribution and morphology (MDM) proteins Pkinase PF00069.20 KLO18937.1 - 1.1e-71 241.0 0.0 1.7e-71 240.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KLO18937.1 - 4.3e-32 111.1 0.0 8.1e-32 110.3 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KLO18937.1 - 4.4e-06 25.8 0.0 6.7e-06 25.2 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 KLO18937.1 - 0.00064 18.8 0.7 0.0011 18.0 0.0 1.7 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KLO18937.1 - 0.011 15.4 0.0 0.1 12.2 0.1 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.4 KLO18937.1 - 0.013 14.7 0.7 0.033 13.5 0.0 1.9 3 0 0 3 3 3 0 PhoP regulatory network protein YrbL DUF2013 PF09431.5 KLO18938.1 - 2.5e-45 153.6 2.1 2.5e-45 153.6 1.4 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF2013) ATP-synt PF00231.14 KLO18939.1 - 5.7e-75 252.3 2.1 6.8e-75 252.1 1.5 1.1 1 0 0 1 1 1 1 ATP synthase eIF-5_eIF-2B PF01873.12 KLO18940.1 - 4.5e-39 132.9 0.2 7.3e-39 132.2 0.2 1.3 1 0 0 1 1 1 1 Domain found in IF2B/IF5 Arc_trans_TRASH PF08394.5 KLO18940.1 - 0.38 10.9 9.1 0.16 12.1 0.4 2.7 1 1 1 2 2 2 0 Archaeal TRASH domain WD40 PF00400.27 KLO18941.1 - 4.7e-38 127.7 0.1 1.1e-08 34.6 0.0 7.3 7 0 0 7 7 7 5 WD domain, G-beta repeat eIF2A PF08662.6 KLO18941.1 - 0.00011 21.9 0.1 0.17 11.5 0.0 3.4 2 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A BBS2_Mid PF14783.1 KLO18941.1 - 0.11 12.3 0.0 0.49 10.1 0.0 2.1 2 1 0 2 2 2 0 Ciliary BBSome complex subunit 2, middle region IKI3 PF04762.7 KLO18941.1 - 0.17 9.6 0.0 1.1 7.0 0.0 1.9 2 0 0 2 2 2 0 IKI3 family UPF0029 PF01205.14 KLO18942.1 - 4.2e-20 71.4 0.2 9.6e-20 70.3 0.0 1.7 2 0 0 2 2 2 1 Uncharacterized protein family UPF0029 Nup54 PF13874.1 KLO18943.1 - 6.3e-31 106.9 1.3 6.3e-31 106.9 0.9 1.7 2 0 0 2 2 2 1 Nucleoporin complex subunit 54 Nucleoporin_FG PF13634.1 KLO18943.1 - 8.1e-14 51.8 110.0 1.9e-09 37.7 31.4 3.7 1 1 2 3 3 3 3 Nucleoporin FG repeat region SlyX PF04102.7 KLO18943.1 - 1.6 9.1 14.5 10 6.5 0.2 4.4 3 1 1 4 4 4 0 SlyX ABC_tran PF00005.22 KLO18944.1 - 1.6e-47 161.2 0.8 6.7e-28 97.6 0.0 3.3 3 1 1 4 4 3 2 ABC transporter ABC_membrane PF00664.18 KLO18944.1 - 2.2e-30 106.0 23.3 3.1e-16 59.6 4.2 3.3 3 0 0 3 3 3 3 ABC transporter transmembrane region SMC_N PF02463.14 KLO18944.1 - 4e-12 45.8 0.0 0.00051 19.3 0.0 3.6 2 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 KLO18944.1 - 2.4e-11 44.1 0.8 0.0049 16.8 0.0 4.4 3 1 0 4 4 4 3 AAA domain AAA_23 PF13476.1 KLO18944.1 - 1.5e-06 28.6 6.2 0.00017 21.9 0.0 3.1 4 0 0 4 4 3 2 AAA domain AAA_16 PF13191.1 KLO18944.1 - 1.8e-06 28.0 0.2 0.086 12.8 0.0 2.9 2 1 0 2 2 2 2 AAA ATPase domain AAA_25 PF13481.1 KLO18944.1 - 9.1e-06 25.2 0.0 0.13 11.6 0.0 2.7 2 0 0 2 2 2 2 AAA domain FtsK_SpoIIIE PF01580.13 KLO18944.1 - 5.6e-05 22.6 0.0 0.031 13.7 0.0 2.4 2 0 0 2 2 2 1 FtsK/SpoIIIE family T2SE PF00437.15 KLO18944.1 - 6.2e-05 22.0 0.0 0.3 9.9 0.0 2.3 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_29 PF13555.1 KLO18944.1 - 6.8e-05 22.3 0.1 0.11 12.0 0.1 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain Miro PF08477.8 KLO18944.1 - 0.00027 21.4 0.0 0.78 10.2 0.0 3.0 2 0 0 2 2 2 2 Miro-like protein AAA_17 PF13207.1 KLO18944.1 - 0.00034 21.4 1.0 0.6 10.9 0.0 3.3 2 1 0 2 2 2 1 AAA domain AAA_18 PF13238.1 KLO18944.1 - 0.00054 20.2 0.0 2.5 8.4 0.0 3.1 2 0 0 2 2 2 2 AAA domain Zeta_toxin PF06414.7 KLO18944.1 - 0.0024 17.0 0.0 1.4 7.9 0.0 2.5 2 0 0 2 2 2 2 Zeta toxin AAA_22 PF13401.1 KLO18944.1 - 0.0032 17.5 1.5 1.5 8.9 0.0 3.8 3 1 0 3 3 3 1 AAA domain MMR_HSR1 PF01926.18 KLO18944.1 - 0.0034 17.3 0.1 0.64 9.9 0.1 2.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase ResIII PF04851.10 KLO18944.1 - 0.0063 16.3 0.0 4 7.2 0.0 3.0 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit Arch_ATPase PF01637.13 KLO18944.1 - 0.0065 16.1 0.2 0.24 11.0 0.0 2.9 2 1 0 2 2 2 1 Archaeal ATPase DUF258 PF03193.11 KLO18944.1 - 0.0074 15.4 0.0 3.2 6.9 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF258 Adeno_IVa2 PF02456.10 KLO18944.1 - 0.0083 14.8 0.0 0.017 13.8 0.0 1.4 1 0 0 1 1 1 1 Adenovirus IVa2 protein MobB PF03205.9 KLO18944.1 - 0.012 15.2 0.4 6.5 6.4 0.2 2.6 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B IstB_IS21 PF01695.12 KLO18944.1 - 0.013 14.9 1.3 4.4 6.6 0.0 3.3 3 1 1 4 4 4 0 IstB-like ATP binding protein ATP-synt_ab PF00006.20 KLO18944.1 - 0.014 14.9 0.2 1.2 8.5 0.0 2.5 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_5 PF07728.9 KLO18944.1 - 0.017 14.8 0.5 6.9 6.3 0.0 3.3 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) RNA_helicase PF00910.17 KLO18944.1 - 0.021 14.9 0.0 4.1 7.6 0.0 2.7 2 0 0 2 2 2 0 RNA helicase DUF87 PF01935.12 KLO18944.1 - 0.035 13.9 0.2 0.55 10.0 0.2 2.4 2 0 0 2 2 2 0 Domain of unknown function DUF87 AAA PF00004.24 KLO18944.1 - 0.048 13.8 3.5 0.16 12.2 0.1 3.1 3 1 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) NB-ARC PF00931.17 KLO18944.1 - 0.065 12.0 0.5 4.5 6.0 0.0 3.0 3 0 0 3 3 3 0 NB-ARC domain AAA_10 PF12846.2 KLO18944.1 - 0.11 11.9 1.4 7.2 5.9 0.4 2.8 2 1 0 2 2 2 0 AAA-like domain AAA_15 PF13175.1 KLO18944.1 - 0.22 10.5 0.0 0.59 9.1 0.0 1.6 2 0 0 2 2 2 0 AAA ATPase domain ABC_tran PF00005.22 KLO18945.1 - 1e-47 161.8 0.2 6.1e-29 101.0 0.0 3.1 3 0 0 3 3 2 2 ABC transporter ABC_membrane PF00664.18 KLO18945.1 - 6.5e-28 97.9 23.7 2.6e-15 56.6 6.5 3.4 3 0 0 3 3 3 2 ABC transporter transmembrane region SMC_N PF02463.14 KLO18945.1 - 9.3e-13 47.9 4.7 0.0058 15.8 0.1 4.1 3 1 0 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 KLO18945.1 - 3.2e-12 47.0 1.6 0.0084 16.0 0.0 4.4 3 1 1 4 4 4 2 AAA domain AAA_25 PF13481.1 KLO18945.1 - 6.9e-08 32.1 0.0 0.0082 15.5 0.0 2.7 3 0 0 3 3 2 2 AAA domain T2SE PF00437.15 KLO18945.1 - 4.3e-07 29.1 0.0 0.018 13.9 0.0 2.3 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_29 PF13555.1 KLO18945.1 - 4.6e-06 26.0 0.5 0.055 12.9 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_17 PF13207.1 KLO18945.1 - 7.2e-06 26.8 0.1 0.12 13.2 0.0 3.4 3 0 0 3 3 2 2 AAA domain AAA_23 PF13476.1 KLO18945.1 - 7.5e-06 26.4 9.6 8e-05 23.0 0.0 2.9 3 0 0 3 3 2 2 AAA domain FtsK_SpoIIIE PF01580.13 KLO18945.1 - 1.2e-05 24.8 0.1 0.11 11.9 0.0 2.4 2 0 0 2 2 2 2 FtsK/SpoIIIE family AAA_16 PF13191.1 KLO18945.1 - 1.4e-05 25.1 0.3 0.16 11.9 0.1 2.9 2 1 0 2 2 2 2 AAA ATPase domain AAA_18 PF13238.1 KLO18945.1 - 7.4e-05 23.0 0.1 0.56 10.5 0.0 2.9 3 0 0 3 3 2 2 AAA domain DUF258 PF03193.11 KLO18945.1 - 0.00016 20.8 0.0 0.49 9.5 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 MMR_HSR1 PF01926.18 KLO18945.1 - 0.00022 21.1 0.5 0.081 12.8 0.1 2.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase Miro PF08477.8 KLO18945.1 - 0.0006 20.3 0.0 2.8 8.4 0.0 3.1 2 0 0 2 2 2 2 Miro-like protein Zeta_toxin PF06414.7 KLO18945.1 - 0.00062 18.9 0.1 0.54 9.3 0.0 2.4 2 0 0 2 2 2 2 Zeta toxin IstB_IS21 PF01695.12 KLO18945.1 - 0.00085 18.7 0.3 1.7 8.0 0.0 3.1 3 0 0 3 3 3 1 IstB-like ATP binding protein MobB PF03205.9 KLO18945.1 - 0.0011 18.6 1.3 1.3 8.6 0.3 2.5 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B AAA_22 PF13401.1 KLO18945.1 - 0.0013 18.8 0.2 2 8.5 0.0 3.5 3 0 0 3 3 3 1 AAA domain DUF87 PF01935.12 KLO18945.1 - 0.0026 17.6 0.9 0.11 12.3 0.1 2.5 2 0 0 2 2 2 1 Domain of unknown function DUF87 ResIII PF04851.10 KLO18945.1 - 0.0038 17.0 1.5 3.6 7.3 0.0 3.1 3 0 0 3 3 2 1 Type III restriction enzyme, res subunit TrwB_AAD_bind PF10412.4 KLO18945.1 - 0.0059 15.2 0.4 1 7.9 0.1 2.4 2 0 0 2 2 2 1 Type IV secretion-system coupling protein DNA-binding domain ATP-synt_ab PF00006.20 KLO18945.1 - 0.0076 15.7 0.0 0.28 10.6 0.0 2.5 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain ArgK PF03308.11 KLO18945.1 - 0.0088 14.8 0.0 0.017 13.9 0.0 1.4 1 0 0 1 1 1 1 ArgK protein AAA_5 PF07728.9 KLO18945.1 - 0.01 15.5 0.9 9.4 5.9 0.0 3.5 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) Pox_A32 PF04665.7 KLO18945.1 - 0.014 14.7 0.4 2 7.6 0.0 2.3 2 0 0 2 2 2 0 Poxvirus A32 protein Adeno_IVa2 PF02456.10 KLO18945.1 - 0.015 13.9 0.0 0.042 12.4 0.0 1.6 2 0 0 2 2 2 0 Adenovirus IVa2 protein AAA_10 PF12846.2 KLO18945.1 - 0.015 14.7 2.5 2.3 7.5 0.1 2.9 2 1 0 3 3 3 0 AAA-like domain AAA_15 PF13175.1 KLO18945.1 - 0.02 13.9 0.0 0.11 11.5 0.0 2.0 2 0 0 2 2 2 0 AAA ATPase domain AAA_30 PF13604.1 KLO18945.1 - 0.027 14.0 4.3 2.7 7.5 0.0 3.2 4 0 0 4 4 4 0 AAA domain NB-ARC PF00931.17 KLO18945.1 - 0.03 13.1 0.3 1.2 7.9 0.0 2.8 2 1 0 2 2 2 0 NB-ARC domain DEAD PF00270.24 KLO18945.1 - 0.036 13.5 0.1 2.7 7.4 0.0 2.8 3 0 0 3 3 3 0 DEAD/DEAH box helicase UPF0079 PF02367.12 KLO18945.1 - 0.039 13.5 0.1 25 4.5 0.1 3.3 3 0 0 3 3 3 0 Uncharacterised P-loop hydrolase UPF0079 SAPS PF04499.10 KLO18945.1 - 0.054 12.1 0.0 0.34 9.5 0.0 1.9 2 0 0 2 2 2 0 SIT4 phosphatase-associated protein RNA_helicase PF00910.17 KLO18945.1 - 0.087 13.0 0.1 20 5.3 0.0 2.8 2 0 0 2 2 2 0 RNA helicase AAA_33 PF13671.1 KLO18945.1 - 0.095 12.5 0.7 4.9 7.0 0.0 3.0 3 0 0 3 3 3 0 AAA domain AAA_11 PF13086.1 KLO18945.1 - 0.11 12.0 0.0 1.3 8.5 0.0 2.6 2 0 0 2 2 2 0 AAA domain Spore_coat_CotO PF14153.1 KLO18945.1 - 0.24 10.8 3.0 1.2 8.5 0.0 2.2 2 0 0 2 2 2 0 Spore coat protein CotO AAA PF00004.24 KLO18945.1 - 0.3 11.3 3.5 2.1 8.5 0.1 3.4 3 1 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) Dynamin_N PF00350.18 KLO18945.1 - 2.1 8.1 5.2 8.4 6.1 0.0 3.4 4 0 0 4 4 3 0 Dynamin family Abhydrolase_6 PF12697.2 KLO18946.1 - 1.6e-27 96.9 0.0 1.9e-27 96.6 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KLO18946.1 - 2.2e-15 56.8 0.0 9.5e-15 54.7 0.0 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KLO18946.1 - 1.4e-10 41.1 0.0 4.8e-10 39.3 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Thioesterase PF00975.15 KLO18946.1 - 8.9e-05 22.8 0.0 0.00018 21.7 0.0 1.4 1 1 0 1 1 1 1 Thioesterase domain Peptidase_S15 PF02129.13 KLO18946.1 - 0.00016 21.2 0.0 0.00053 19.5 0.0 1.8 3 0 0 3 3 3 1 X-Pro dipeptidyl-peptidase (S15 family) Hydrolase_4 PF12146.3 KLO18946.1 - 0.0042 16.9 0.0 0.0086 15.9 0.0 1.5 1 0 0 1 1 1 1 Putative lysophospholipase DUF1057 PF06342.7 KLO18946.1 - 0.15 10.8 0.0 0.23 10.2 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1057) Abhydrolase_6 PF12697.2 KLO18947.1 - 4.2e-29 102.0 0.2 5.4e-29 101.6 0.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KLO18947.1 - 7e-15 55.2 0.1 2.4e-14 53.4 0.1 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KLO18947.1 - 2.5e-09 37.0 0.0 6.3e-09 35.7 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Thioesterase PF00975.15 KLO18947.1 - 1.8e-05 25.1 0.0 2.5e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 Thioesterase domain Lipase_3 PF01764.20 KLO18947.1 - 0.024 14.2 0.0 0.04 13.5 0.0 1.5 1 0 0 1 1 1 0 Lipase (class 3) DUF915 PF06028.6 KLO18947.1 - 0.038 13.0 0.0 0.061 12.4 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) PGAP1 PF07819.8 KLO18947.1 - 0.056 13.0 0.0 0.085 12.4 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein Peptidase_S15 PF02129.13 KLO18947.1 - 0.075 12.4 0.0 0.57 9.5 0.0 2.1 1 1 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) GCHY-1 PF02649.9 KLO18947.1 - 0.13 11.4 0.0 0.17 11.0 0.0 1.1 1 0 0 1 1 1 0 Type I GTP cyclohydrolase folE2 DUF3328 PF11807.3 KLO18948.1 - 2.3e-21 76.4 0.7 3.3e-21 75.9 0.5 1.5 1 1 0 1 1 1 1 Domain of unknown function (DUF3328) Prefoldin PF02996.12 KLO18949.1 - 8.4e-29 99.6 1.7 9.8e-29 99.4 1.2 1.1 1 0 0 1 1 1 1 Prefoldin subunit Prefoldin_2 PF01920.15 KLO18949.1 - 0.0024 17.6 3.7 0.032 13.9 0.2 2.2 2 0 0 2 2 2 1 Prefoldin subunit Baculo_PEP_C PF04513.7 KLO18949.1 - 0.0026 17.6 1.5 0.19 11.5 0.1 2.1 2 0 0 2 2 2 1 Baculovirus polyhedron envelope protein, PEP, C terminus SH3BP5 PF05276.9 KLO18949.1 - 0.055 12.7 1.8 0.22 10.8 0.1 2.0 2 0 0 2 2 2 0 SH3 domain-binding protein 5 (SH3BP5) CCDC155 PF14662.1 KLO18949.1 - 0.06 12.9 3.2 0.084 12.4 0.1 2.0 2 0 0 2 2 2 0 Coiled-coil region of CCDC155 Mod_r PF07200.8 KLO18949.1 - 0.075 12.9 4.2 0.21 11.4 0.2 2.1 2 0 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein DUF1664 PF07889.7 KLO18949.1 - 0.097 12.4 2.4 1.7 8.4 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) COG2 PF06148.6 KLO18949.1 - 0.12 12.2 5.5 1.5 8.7 0.7 2.1 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 CENP-F_leu_zip PF10473.4 KLO18949.1 - 0.13 12.1 4.0 1.8 8.4 0.3 2.1 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF4172 PF13776.1 KLO18949.1 - 0.16 12.0 1.6 1.7 8.8 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4172) UPF0449 PF15136.1 KLO18949.1 - 0.17 12.1 2.7 3.8 7.7 0.1 2.2 2 0 0 2 2 2 0 Uncharacterised protein family UPF0449 DUF4201 PF13870.1 KLO18949.1 - 0.19 11.1 4.6 0.35 10.2 0.6 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4201) WXG100 PF06013.7 KLO18949.1 - 0.32 11.0 2.9 6.2 6.9 0.1 2.2 2 0 0 2 2 2 0 Proteins of 100 residues with WXG NUDIX PF00293.23 KLO18950.1 - 9.9e-05 21.9 0.0 0.00025 20.6 0.0 1.6 1 0 0 1 1 1 1 NUDIX domain DUF3640 PF12342.3 KLO18950.1 - 0.058 12.9 0.1 0.058 12.9 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3640) ABC_tran PF00005.22 KLO18951.1 - 7.7e-44 149.3 0.1 1.5e-27 96.5 0.0 2.5 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 KLO18951.1 - 9.5e-32 110.4 29.4 2.2e-15 56.8 8.8 3.4 3 0 0 3 3 3 3 ABC transporter transmembrane region AAA_21 PF13304.1 KLO18951.1 - 1e-12 48.6 0.1 0.00033 20.7 0.0 4.6 4 0 0 4 4 4 2 AAA domain SMC_N PF02463.14 KLO18951.1 - 2.7e-12 46.4 1.4 6.6e-05 22.2 0.0 4.1 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_25 PF13481.1 KLO18951.1 - 1.5e-07 31.0 0.2 0.018 14.4 0.0 2.9 3 0 0 3 3 3 2 AAA domain AAA_16 PF13191.1 KLO18951.1 - 4.5e-07 30.0 0.5 0.012 15.5 0.1 2.7 2 1 0 2 2 2 2 AAA ATPase domain T2SE PF00437.15 KLO18951.1 - 4.7e-07 28.9 0.0 0.0063 15.4 0.0 2.5 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_29 PF13555.1 KLO18951.1 - 4.9e-07 29.1 0.3 0.016 14.7 0.1 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain FtsK_SpoIIIE PF01580.13 KLO18951.1 - 1.6e-06 27.7 0.1 0.015 14.7 0.0 2.7 3 0 0 3 3 2 2 FtsK/SpoIIIE family AAA_23 PF13476.1 KLO18951.1 - 2.8e-06 27.8 9.7 0.014 15.7 5.0 3.3 2 1 0 2 2 2 2 AAA domain AAA_17 PF13207.1 KLO18951.1 - 1.7e-05 25.6 0.9 0.16 12.7 0.0 3.2 3 1 0 3 3 2 2 AAA domain AAA_18 PF13238.1 KLO18951.1 - 4.2e-05 23.8 0.1 0.38 11.0 0.0 2.7 2 0 0 2 2 2 2 AAA domain IstB_IS21 PF01695.12 KLO18951.1 - 0.00039 19.8 0.3 0.34 10.3 0.0 3.3 3 0 0 3 3 3 1 IstB-like ATP binding protein AAA_22 PF13401.1 KLO18951.1 - 0.00044 20.4 2.1 0.99 9.5 0.0 3.5 2 1 0 2 2 2 1 AAA domain DUF87 PF01935.12 KLO18951.1 - 0.00061 19.6 0.7 0.024 14.4 0.1 2.4 2 0 0 2 2 2 1 Domain of unknown function DUF87 AAA_10 PF12846.2 KLO18951.1 - 0.00068 19.1 2.6 0.87 8.9 0.0 3.5 3 1 0 4 4 4 1 AAA-like domain AAA_19 PF13245.1 KLO18951.1 - 0.0007 19.3 0.1 0.13 12.0 0.0 3.0 2 0 0 2 2 2 1 Part of AAA domain MobB PF03205.9 KLO18951.1 - 0.0009 18.9 0.5 0.36 10.5 0.1 2.8 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B MMR_HSR1 PF01926.18 KLO18951.1 - 0.0014 18.5 0.0 0.046 13.6 0.0 2.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase DEAD PF00270.24 KLO18951.1 - 0.0023 17.4 0.6 1 8.8 0.0 2.8 2 1 0 2 2 2 1 DEAD/DEAH box helicase NTPase_1 PF03266.10 KLO18951.1 - 0.0026 17.5 1.4 0.18 11.5 0.1 3.0 3 0 0 3 3 3 1 NTPase Zeta_toxin PF06414.7 KLO18951.1 - 0.0031 16.6 0.1 2.4 7.1 0.0 2.4 2 0 0 2 2 2 2 Zeta toxin Arch_ATPase PF01637.13 KLO18951.1 - 0.0032 17.2 0.2 0.81 9.3 0.0 3.4 3 1 0 3 3 2 1 Archaeal ATPase ATP-synt_ab PF00006.20 KLO18951.1 - 0.0036 16.8 0.0 0.02 14.3 0.0 2.0 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain Miro PF08477.8 KLO18951.1 - 0.0042 17.5 0.0 5.4 7.5 0.0 2.6 2 0 0 2 2 2 0 Miro-like protein DUF2075 PF09848.4 KLO18951.1 - 0.005 15.8 0.0 0.64 8.9 0.0 2.3 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) TrwB_AAD_bind PF10412.4 KLO18951.1 - 0.008 14.8 0.4 0.65 8.5 0.0 2.3 2 0 0 2 2 2 1 Type IV secretion-system coupling protein DNA-binding domain AAA_30 PF13604.1 KLO18951.1 - 0.0099 15.4 3.1 1.1 8.7 0.8 2.9 2 1 0 2 2 2 1 AAA domain DUF258 PF03193.11 KLO18951.1 - 0.01 15.0 0.0 0.35 10.0 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function, DUF258 ResIII PF04851.10 KLO18951.1 - 0.012 15.4 0.0 4.7 7.0 0.0 2.8 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit Pox_A32 PF04665.7 KLO18951.1 - 0.017 14.3 0.4 4.6 6.4 0.0 2.3 2 0 0 2 2 2 0 Poxvirus A32 protein AAA PF00004.24 KLO18951.1 - 0.021 15.0 0.3 1.5 8.9 0.0 3.1 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) APS_kinase PF01583.15 KLO18951.1 - 0.021 14.4 1.1 4 7.0 0.1 3.2 4 0 0 4 4 3 0 Adenylylsulphate kinase TIP49 PF06068.8 KLO18951.1 - 0.024 13.3 0.0 5.4 5.6 0.0 2.3 2 0 0 2 2 2 0 TIP49 C-terminus AAA_33 PF13671.1 KLO18951.1 - 0.03 14.2 0.0 2.6 7.9 0.0 2.5 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.17 KLO18951.1 - 0.03 14.4 0.0 6.9 6.9 0.0 2.8 2 0 0 2 2 2 0 RNA helicase AAA_5 PF07728.9 KLO18951.1 - 0.048 13.3 0.8 9.8 5.9 0.0 3.5 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) AAA_28 PF13521.1 KLO18951.1 - 0.074 13.0 0.0 15 5.4 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.1 KLO18951.1 - 0.098 12.5 0.1 8.3 6.3 0.0 3.1 3 0 0 3 3 3 0 AAA domain AAA_15 PF13175.1 KLO18951.1 - 0.12 11.4 0.0 0.79 8.6 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain ABC_ATPase PF09818.4 KLO18951.1 - 1.5 7.3 4.1 1 7.8 0.2 2.4 3 0 0 3 3 3 0 Predicted ATPase of the ABC class AIF-MLS PF14962.1 KLO18952.1 - 0.12 12.0 0.0 0.15 11.7 0.0 1.1 1 0 0 1 1 1 0 Mitochondria Localisation Sequence Peptidase_S10 PF00450.17 KLO18953.1 - 2.4e-189 629.7 0.3 3.7e-98 329.4 0.0 3.0 3 0 0 3 3 3 3 Serine carboxypeptidase Abhydrolase_6 PF12697.2 KLO18953.1 - 2e-09 37.6 0.4 0.023 14.5 0.0 4.1 3 1 0 3 3 3 3 Alpha/beta hydrolase family Dioxygenase_C PF00775.16 KLO18953.1 - 0.098 11.9 0.0 9 5.5 0.0 2.3 2 0 0 2 2 2 0 Dioxygenase BRO1 PF03097.13 KLO18954.1 - 1.6e-115 385.9 1.4 1.7e-115 385.8 0.1 1.6 2 0 0 2 2 2 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.1 KLO18954.1 - 3.2e-61 206.9 6.3 4.9e-61 206.2 4.3 1.3 1 0 0 1 1 1 1 ALIX V-shaped domain binding to HIV Usp PF00582.21 KLO18955.1 - 1.9e-14 54.0 0.0 2.3e-14 53.7 0.0 1.1 1 0 0 1 1 1 1 Universal stress protein family WW PF00397.21 KLO18956.1 - 3.6e-07 29.9 2.2 3.6e-07 29.9 1.5 1.7 2 0 0 2 2 2 1 WW domain CinA PF02464.12 KLO18957.1 - 1.5e-36 125.2 0.4 1.8e-36 124.9 0.3 1.0 1 0 0 1 1 1 1 Competence-damaged protein F-box-like PF12937.2 KLO18958.1 - 1.1e-08 34.6 3.2 8e-07 28.6 0.1 3.6 3 0 0 3 3 3 2 F-box-like F-box-like PF12937.2 KLO18959.1 - 3.4e-08 33.0 0.2 1.7e-06 27.6 0.1 2.9 2 0 0 2 2 2 1 F-box-like FHA PF00498.21 KLO18960.1 - 1.9e-05 24.6 0.0 4e-05 23.6 0.0 1.5 1 0 0 1 1 1 1 FHA domain ABC_tran PF00005.22 KLO18961.1 - 4.7e-44 149.9 0.1 5.3e-26 91.5 0.1 2.7 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 KLO18961.1 - 5e-32 111.4 40.8 4.1e-19 69.0 1.0 3.9 4 0 0 4 4 4 2 ABC transporter transmembrane region SMC_N PF02463.14 KLO18961.1 - 2.4e-13 49.8 2.7 0.0011 18.2 0.0 4.3 4 1 0 4 4 3 3 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 KLO18961.1 - 2.2e-12 47.5 0.6 0.0019 18.1 0.0 4.5 3 1 0 3 3 3 3 AAA domain AAA_16 PF13191.1 KLO18961.1 - 2e-05 24.6 0.2 0.11 12.4 0.1 2.7 2 0 0 2 2 2 2 AAA ATPase domain AAA_25 PF13481.1 KLO18961.1 - 3e-05 23.5 0.1 0.13 11.6 0.0 2.6 2 0 0 2 2 2 2 AAA domain FtsK_SpoIIIE PF01580.13 KLO18961.1 - 3.5e-05 23.3 0.4 0.3 10.5 0.0 2.8 3 0 0 3 3 3 2 FtsK/SpoIIIE family AAA_29 PF13555.1 KLO18961.1 - 8.4e-05 22.0 0.5 0.29 10.6 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain T2SE PF00437.15 KLO18961.1 - 0.00012 21.0 0.0 0.075 11.9 0.0 2.8 3 0 0 3 3 3 1 Type II/IV secretion system protein Miro PF08477.8 KLO18961.1 - 0.00026 21.4 0.1 0.66 10.4 0.0 3.4 4 0 0 4 4 2 1 Miro-like protein AAA_18 PF13238.1 KLO18961.1 - 0.00034 20.9 0.0 0.62 10.3 0.0 2.9 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.18 KLO18961.1 - 0.00045 20.1 0.1 0.27 11.1 0.0 2.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_23 PF13476.1 KLO18961.1 - 0.00051 20.4 14.4 0.0014 18.9 4.5 3.8 3 1 0 3 3 3 1 AAA domain ResIII PF04851.10 KLO18961.1 - 0.00066 19.5 0.1 2.5 7.8 0.0 3.4 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit AAA_17 PF13207.1 KLO18961.1 - 0.00079 20.2 0.0 1.1 10.0 0.0 3.1 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.7 KLO18961.1 - 0.0012 18.0 0.0 0.93 8.5 0.0 2.3 2 0 0 2 2 2 2 Zeta toxin MobB PF03205.9 KLO18961.1 - 0.0017 18.1 0.8 1.6 8.4 0.0 2.7 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B AAA_22 PF13401.1 KLO18961.1 - 0.0024 18.0 0.1 1.4 9.0 0.0 3.7 4 0 0 4 4 3 1 AAA domain DUF258 PF03193.11 KLO18961.1 - 0.0048 16.0 0.1 1.9 7.6 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF258 DEAD PF00270.24 KLO18961.1 - 0.006 16.0 0.7 0.77 9.2 0.0 2.8 2 1 0 2 2 2 1 DEAD/DEAH box helicase Dynamin_N PF00350.18 KLO18961.1 - 0.012 15.4 1.0 5.4 6.8 0.0 3.1 3 0 0 3 3 3 0 Dynamin family IstB_IS21 PF01695.12 KLO18961.1 - 0.017 14.5 2.3 8.1 5.8 0.0 3.7 4 0 0 4 4 3 0 IstB-like ATP binding protein AAA_19 PF13245.1 KLO18961.1 - 0.02 14.6 0.6 1.2 8.8 0.0 3.4 4 0 0 4 4 2 0 Part of AAA domain Adeno_IVa2 PF02456.10 KLO18961.1 - 0.02 13.5 0.0 0.045 12.4 0.0 1.5 1 0 0 1 1 1 0 Adenovirus IVa2 protein AAA_15 PF13175.1 KLO18961.1 - 0.046 12.7 0.0 0.11 11.5 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain AAA_26 PF13500.1 KLO18961.1 - 0.054 13.1 0.5 6.4 6.3 0.2 2.5 2 0 0 2 2 2 0 AAA domain DUF87 PF01935.12 KLO18961.1 - 0.064 13.0 5.1 1.1 9.0 0.3 2.9 3 0 0 3 3 3 0 Domain of unknown function DUF87 AAA_5 PF07728.9 KLO18961.1 - 0.072 12.8 0.1 11 5.7 0.0 2.8 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA PF00004.24 KLO18961.1 - 0.12 12.5 1.6 3 8.0 0.1 3.7 4 1 0 4 4 4 0 ATPase family associated with various cellular activities (AAA) DUF4027 PF13219.1 KLO18961.1 - 0.14 11.6 0.8 0.62 9.5 0.5 2.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4027) AAA_10 PF12846.2 KLO18961.1 - 0.17 11.2 1.8 10 5.4 0.0 3.0 3 0 0 3 3 3 0 AAA-like domain Arch_ATPase PF01637.13 KLO18961.1 - 0.18 11.5 3.2 0.75 9.4 0.0 3.1 3 1 0 3 3 2 0 Archaeal ATPase DDE_1 PF03184.14 KLO18966.1 - 7.7e-16 57.8 0.0 1.7e-15 56.7 0.0 1.5 2 0 0 2 2 2 1 DDE superfamily endonuclease DDE_3 PF13358.1 KLO18966.1 - 0.14 11.8 0.0 0.24 11.1 0.0 1.4 2 0 0 2 2 2 0 DDE superfamily endonuclease Ish1 PF10281.4 KLO18967.1 - 0.068 13.2 0.5 0.3 11.2 0.2 2.2 2 0 0 2 2 2 0 Putative stress-responsive nuclear envelope protein Bestrophin PF01062.16 KLO18968.1 - 2e-47 161.5 0.0 3.4e-30 105.0 0.0 2.1 2 0 0 2 2 2 2 Bestrophin, RFP-TM, chloride channel DUF4229 PF14012.1 KLO18968.1 - 0.15 11.9 2.1 0.39 10.6 1.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF4229) DUF952 PF06108.7 KLO18969.1 - 5.9e-22 77.3 0.0 8.7e-22 76.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF952) Pkinase_Tyr PF07714.12 KLO18970.1 - 6.2e-31 107.4 0.0 6.9e-31 107.2 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 KLO18970.1 - 5.2e-30 104.4 0.0 5.7e-30 104.3 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.1 KLO18970.1 - 0.00027 19.9 0.0 0.00038 19.5 0.0 1.1 1 0 0 1 1 1 1 Kinase-like DUF1785 PF08699.5 KLO18970.1 - 0.091 12.1 0.1 0.28 10.5 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF1785) TFIIS_C PF01096.13 KLO18971.1 - 4.3e-12 45.4 0.9 4.3e-12 45.4 0.6 2.8 2 1 0 2 2 1 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.11 KLO18971.1 - 1.4e-11 43.9 1.3 1.4e-11 43.9 0.9 3.6 4 0 0 4 4 4 1 RNA polymerases M/15 Kd subunit Lar_restr_allev PF14354.1 KLO18971.1 - 0.0012 19.1 0.5 0.0012 19.1 0.4 2.2 2 1 0 2 2 2 1 Restriction alleviation protein Lar GFA PF04828.9 KLO18971.1 - 0.027 14.3 4.2 3.2 7.7 0.9 2.6 1 1 1 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme Zn_Tnp_IS1 PF03811.8 KLO18971.1 - 0.051 13.0 1.2 0.051 13.0 0.9 2.8 3 2 0 3 3 2 0 InsA N-terminal domain C1_4 PF07975.7 KLO18971.1 - 0.077 13.0 10.9 0.32 11.0 1.0 2.8 2 1 1 3 3 3 0 TFIIH C1-like domain IBR PF01485.16 KLO18971.1 - 0.14 12.0 5.6 2.2 8.2 0.4 2.3 2 1 0 2 2 2 0 IBR domain OrfB_Zn_ribbon PF07282.6 KLO18971.1 - 0.15 11.7 7.3 1.1 8.9 1.0 2.6 2 1 0 2 2 2 0 Putative transposase DNA-binding domain RRN7 PF11781.3 KLO18971.1 - 0.18 11.3 10.5 0.84 9.1 0.6 3.9 4 0 0 4 4 4 0 RNA polymerase I-specific transcription initiation factor Rrn7 FYVE PF01363.16 KLO18971.1 - 0.22 11.4 5.5 2.9 7.8 0.2 2.3 2 0 0 2 2 2 0 FYVE zinc finger DZR PF12773.2 KLO18971.1 - 0.26 11.1 9.3 2.7 7.8 0.6 2.9 2 1 0 2 2 2 0 Double zinc ribbon UPF0547 PF10571.4 KLO18971.1 - 0.27 10.9 10.7 4.8 6.9 0.0 4.1 4 0 0 4 4 4 0 Uncharacterised protein family UPF0547 DUF2387 PF09526.5 KLO18971.1 - 0.28 11.1 5.7 0.31 11.0 0.3 2.3 2 0 0 2 2 2 0 Probable metal-binding protein (DUF2387) Elf1 PF05129.8 KLO18971.1 - 0.34 10.6 5.7 5.7 6.6 0.2 2.7 2 1 0 2 2 2 0 Transcription elongation factor Elf1 like zf-ISL3 PF14690.1 KLO18971.1 - 0.41 10.7 0.0 0.41 10.7 0.0 3.2 3 1 1 4 4 4 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 Rpr2 PF04032.11 KLO18971.1 - 0.66 9.8 6.8 5.7 6.8 4.8 2.3 1 1 1 2 2 2 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain zf-FPG_IleRS PF06827.9 KLO18971.1 - 1.8 8.3 0.0 1.8 8.3 0.0 3.3 4 0 0 4 4 3 0 Zinc finger found in FPG and IleRS Rubredoxin PF00301.15 KLO18971.1 - 1.9 8.4 9.4 22 5.0 0.0 3.9 4 0 0 4 4 4 0 Rubredoxin Zn_Tnp_IS1595 PF12760.2 KLO18971.1 - 2.1 8.2 9.7 20 5.0 0.4 3.1 2 1 0 2 2 2 0 Transposase zinc-ribbon domain Zn-ribbon_8 PF09723.5 KLO18971.1 - 2.4 8.2 9.6 8.7 6.3 0.1 3.6 4 0 0 4 4 4 0 Zinc ribbon domain zf-Mss51 PF13824.1 KLO18971.1 - 2.6 7.9 5.5 0.74 9.7 1.4 2.2 1 1 1 2 2 2 0 Zinc-finger of mitochondrial splicing suppressor 51 C1_1 PF00130.17 KLO18971.1 - 3 7.6 8.3 0.14 11.9 0.5 2.4 2 1 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-ribbon_3 PF13248.1 KLO18971.1 - 3 7.1 12.2 1.5 8.1 0.1 3.6 4 0 0 4 4 4 0 zinc-ribbon domain TF_Zn_Ribbon PF08271.7 KLO18971.1 - 3.1 7.1 11.5 0.78 9.1 2.4 3.2 3 1 0 3 3 3 0 TFIIB zinc-binding DUF1610 PF07754.6 KLO18971.1 - 3.2 7.9 10.5 13 5.9 2.1 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF1610) zf-C2HC5 PF06221.8 KLO18971.1 - 3.4 7.5 9.4 4.9 6.9 0.0 3.5 3 1 1 4 4 4 0 Putative zinc finger motif, C2HC5-type zf-CHY PF05495.7 KLO18971.1 - 4.3 7.5 8.3 10 6.3 0.6 2.5 2 1 0 2 2 2 0 CHY zinc finger Prim_Zn_Ribbon PF08273.7 KLO18971.1 - 4.3 7.5 11.7 0.65 10.1 2.1 3.2 3 1 0 3 3 3 0 Zinc-binding domain of primase-helicase zf-H2C2_2 PF13465.1 KLO18971.1 - 4.8 7.6 7.3 36 4.9 0.1 3.8 4 0 0 4 4 4 0 Zinc-finger double domain NOB1_Zn_bind PF08772.6 KLO18971.1 - 6.9 6.5 8.1 48 3.8 0.0 3.5 4 0 0 4 4 3 0 Nin one binding (NOB1) Zn-ribbon like zf-RING_3 PF14369.1 KLO18971.1 - 7.2 6.7 11.4 9 6.3 0.5 3.1 3 0 0 3 3 3 0 zinc-finger zinc_ribbon_2 PF13240.1 KLO18971.1 - 8.4 6.0 11.2 4.4 6.9 0.5 3.1 3 0 0 3 3 3 0 zinc-ribbon domain RecR PF02132.10 KLO18971.1 - 9.8 5.7 14.0 15 5.1 3.7 3.6 3 1 0 3 3 3 0 RecR protein G-alpha PF00503.15 KLO18972.1 - 6.9e-108 360.7 0.0 7.8e-108 360.6 0.0 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 KLO18972.1 - 5.7e-15 54.9 0.3 5.8e-10 38.6 0.1 2.3 2 0 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.7 KLO18972.1 - 0.0045 16.1 0.3 0.43 9.6 0.0 2.3 2 0 0 2 2 2 2 Gtr1/RagA G protein conserved region FtsK_SpoIIIE PF01580.13 KLO18972.1 - 0.029 13.8 0.0 0.052 13.0 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_29 PF13555.1 KLO18972.1 - 0.088 12.3 0.0 0.2 11.1 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_22 PF13401.1 KLO18972.1 - 0.091 12.9 0.0 0.22 11.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain Glucan_synthase PF02364.10 KLO18974.1 - 0 1375.1 0.0 0 1374.6 0.0 1.2 1 0 0 1 1 1 1 1,3-beta-glucan synthase component FKS1_dom1 PF14288.1 KLO18974.1 - 4.6e-37 126.4 0.3 1.1e-36 125.2 0.2 1.7 1 0 0 1 1 1 1 1,3-beta-glucan synthase subunit FKS1, domain-1 AA_permease_2 PF13520.1 KLO18976.1 - 1e-53 182.4 53.6 1.3e-53 182.1 37.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 KLO18976.1 - 1.6e-22 79.5 48.7 2.2e-22 79.0 33.8 1.1 1 0 0 1 1 1 1 Amino acid permease Amidase PF01425.16 KLO18977.1 - 5e-80 269.5 0.0 4.9e-78 262.9 0.0 2.0 1 1 0 1 1 1 1 Amidase AAA PF00004.24 KLO18978.1 - 5.3e-12 46.0 0.0 7.5e-11 42.3 0.0 2.6 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 KLO18978.1 - 0.039 13.6 0.0 1.1 9.0 0.0 2.5 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) ArgK PF03308.11 KLO18978.1 - 0.073 11.8 0.1 0.12 11.0 0.0 1.3 1 0 0 1 1 1 0 ArgK protein AAA_22 PF13401.1 KLO18978.1 - 0.13 12.3 0.3 2.4 8.2 0.0 2.8 2 1 1 3 3 3 0 AAA domain F-box-like PF12937.2 KLO18979.1 - 3.4e-11 42.6 0.2 2.5e-10 39.9 0.0 2.5 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 KLO18979.1 - 1.2 8.9 10.2 0.12 12.0 2.5 2.9 2 1 0 2 2 2 0 F-box domain F-box-like PF12937.2 KLO18980.1 - 2.2e-07 30.4 0.1 7e-07 28.8 0.1 1.9 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KLO18980.1 - 0.69 9.6 4.1 1.7 8.3 0.3 3.0 3 1 0 3 3 3 0 F-box domain Pro_isomerase PF00160.16 KLO18981.1 - 2.4e-44 151.2 0.1 3.5e-44 150.7 0.1 1.3 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD TPR_11 PF13414.1 KLO18981.1 - 1e-08 34.6 0.4 6.4e-05 22.5 0.3 2.4 1 1 0 1 1 1 1 TPR repeat TPR_2 PF07719.12 KLO18981.1 - 5.4e-06 25.9 0.7 0.031 14.1 0.1 2.8 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.23 KLO18981.1 - 0.00048 19.6 0.2 0.089 12.4 0.0 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_6 PF13174.1 KLO18981.1 - 1.6 9.3 3.9 2.6 8.6 0.1 3.2 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF588 PF04535.7 KLO18982.1 - 0.0022 17.5 1.3 0.0022 17.5 0.9 2.1 3 0 0 3 3 3 1 Domain of unknown function (DUF588) DUF983 PF06170.7 KLO18982.1 - 0.32 11.1 5.2 0.2 11.7 0.2 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF983) SH PF01445.12 KLO18982.1 - 2.1 8.0 6.4 7.5 6.2 0.0 3.5 3 0 0 3 3 3 0 Viral small hydrophobic protein zf-C3HC4_2 PF13923.1 KLO18983.1 - 7.7e-10 38.6 20.1 2.4e-05 24.2 1.7 2.4 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KLO18983.1 - 1.2e-08 34.5 17.5 4e-05 23.2 5.8 2.4 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KLO18983.1 - 7.4e-08 31.9 20.1 2.5e-07 30.3 5.5 2.7 2 1 0 2 2 2 2 zinc-RING finger domain zf-RING_2 PF13639.1 KLO18983.1 - 3.1e-07 30.1 16.7 0.00044 20.0 5.8 2.3 2 0 0 2 2 2 2 Ring finger domain Rtf2 PF04641.7 KLO18983.1 - 4.5e-06 26.0 13.3 0.00012 21.3 0.5 2.7 3 0 0 3 3 3 2 Rtf2 RING-finger zf-C3HC4 PF00097.20 KLO18983.1 - 1.6e-05 24.4 18.7 0.014 15.0 1.8 2.4 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.1 KLO18983.1 - 0.00065 19.4 8.5 0.15 11.8 0.1 2.4 2 0 0 2 2 2 2 zf-RING of BARD1-type protein Atg14 PF10186.4 KLO18983.1 - 0.0026 16.7 2.0 0.0026 16.7 1.4 1.8 2 0 0 2 2 1 1 UV radiation resistance protein and autophagy-related subunit 14 zf-rbx1 PF12678.2 KLO18983.1 - 0.087 12.9 9.5 0.084 13.0 2.7 2.4 2 0 0 2 2 2 0 RING-H2 zinc finger zf-C3HC4_4 PF15227.1 KLO18983.1 - 0.11 12.4 17.2 0.18 11.6 1.2 2.6 2 1 0 2 2 2 0 zinc finger of C3HC4-type, RING DZR PF12773.2 KLO18983.1 - 0.52 10.1 12.8 2.2 8.1 3.6 3.0 2 1 0 2 2 2 0 Double zinc ribbon zf-RING_UBOX PF13445.1 KLO18983.1 - 0.99 9.1 15.6 1.7 8.4 5.1 2.6 2 0 0 2 2 2 0 RING-type zinc-finger Cgr1 PF03879.9 KLO18983.1 - 3.3 7.9 9.0 9.3 6.4 2.1 2.3 2 0 0 2 2 2 0 Cgr1 family FYVE PF01363.16 KLO18983.1 - 6.9 6.6 14.8 3.1 7.7 3.1 3.0 2 1 0 2 2 2 0 FYVE zinc finger F-box-like PF12937.2 KLO18984.1 - 7.4e-08 32.0 0.1 1.7e-07 30.8 0.1 1.7 1 0 0 1 1 1 1 F-box-like F-box-like PF12937.2 KLO18985.1 - 2.7e-06 27.0 0.3 2.7e-06 27.0 0.2 3.0 3 0 0 3 3 3 1 F-box-like TB2_DP1_HVA22 PF03134.14 KLO18986.1 - 5.7e-27 93.2 2.2 9.2e-27 92.6 1.5 1.3 1 0 0 1 1 1 1 TB2/DP1, HVA22 family TB2_DP1_HVA22 PF03134.14 KLO18987.1 - 1.2e-27 95.4 7.6 1.7e-27 94.9 5.3 1.2 1 0 0 1 1 1 1 TB2/DP1, HVA22 family BAH PF01426.13 KLO18988.1 - 2.5e-08 33.6 0.0 4.3e-08 32.9 0.0 1.4 1 0 0 1 1 1 1 BAH domain Prok-RING_1 PF14446.1 KLO18988.1 - 0.037 13.7 1.8 0.037 13.7 1.2 1.9 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 PHD PF00628.24 KLO18988.1 - 0.041 13.5 10.2 0.046 13.4 2.7 2.6 3 0 0 3 3 3 0 PHD-finger zf-PHD-like PF15446.1 KLO18988.1 - 0.044 13.0 0.3 0.08 12.2 0.2 1.4 1 0 0 1 1 1 0 PHD/FYVE-zinc-finger like domain zf-RING_2 PF13639.1 KLO18988.1 - 0.46 10.3 7.9 0.51 10.2 1.5 2.6 3 0 0 3 3 3 0 Ring finger domain zf-RING_3 PF14369.1 KLO18988.1 - 0.57 10.2 3.9 2.4 8.2 0.1 2.6 2 0 0 2 2 2 0 zinc-finger C1_1 PF00130.17 KLO18988.1 - 1.5 8.5 6.9 0.3 10.8 1.5 2.2 3 0 0 3 3 3 0 Phorbol esters/diacylglycerol binding domain (C1 domain) MCM PF00493.18 KLO18989.1 - 1.3e-136 454.7 0.9 2.4e-136 453.8 0.6 1.4 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 KLO18989.1 - 1.6e-21 76.9 0.1 4.4e-21 75.6 0.1 1.8 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.16 KLO18989.1 - 1.2e-07 31.1 0.0 9.8e-07 28.1 0.0 2.2 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.6 KLO18989.1 - 0.0011 18.5 0.0 0.0049 16.4 0.0 2.1 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 KLO18989.1 - 0.0024 17.3 0.0 0.005 16.3 0.0 1.5 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA_5 PF07728.9 KLO18989.1 - 0.021 14.5 0.0 0.045 13.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) DUF2360 PF10152.4 KLO18989.1 - 1.5 9.0 5.4 0.23 11.7 0.6 2.0 2 0 0 2 2 2 0 Predicted coiled-coil domain-containing protein (DUF2360) SAP30_Sin3_bdg PF13867.1 KLO18990.1 - 0.15 11.9 0.1 0.25 11.2 0.1 1.5 1 1 0 1 1 1 0 Sin3 binding region of histone deacetylase complex subunit SAP30 Thaumatin PF00314.12 KLO18991.1 - 5e-61 205.8 7.1 5.7e-61 205.6 4.9 1.0 1 0 0 1 1 1 1 Thaumatin family ThiF PF00899.16 KLO18992.1 - 6.3e-36 123.1 0.2 1.1e-35 122.4 0.1 1.4 1 0 0 1 1 1 1 ThiF family Saccharop_dh PF03435.13 KLO18992.1 - 0.0021 17.1 0.1 0.005 15.8 0.1 1.6 1 1 0 1 1 1 1 Saccharopine dehydrogenase NAD_binding_7 PF13241.1 KLO18992.1 - 0.0034 17.6 0.2 0.011 15.9 0.1 1.9 2 0 0 2 2 2 1 Putative NAD(P)-binding 3HCDH_N PF02737.13 KLO18992.1 - 0.0075 15.9 0.0 0.015 14.9 0.0 1.6 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ELFV_dehydrog PF00208.16 KLO18992.1 - 0.015 14.9 0.1 0.036 13.6 0.0 1.6 1 1 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase FAD_binding_3 PF01494.14 KLO18992.1 - 0.018 14.0 0.1 0.029 13.4 0.1 1.3 1 0 0 1 1 1 0 FAD binding domain UDPG_MGDP_dh_N PF03721.9 KLO18992.1 - 0.024 14.0 0.4 0.15 11.3 0.0 2.2 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain DAO PF01266.19 KLO18992.1 - 0.029 13.2 0.1 0.042 12.7 0.1 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase Glyco_hydro_17 PF00332.13 KLO18992.1 - 0.078 11.9 0.0 0.13 11.3 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolases family 17 ApbA PF02558.11 KLO18992.1 - 0.089 12.2 0.0 0.17 11.3 0.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA AlaDh_PNT_C PF01262.16 KLO18992.1 - 0.091 12.3 0.2 0.17 11.4 0.1 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain p450 PF00067.17 KLO18993.1 - 1.1e-50 172.5 0.0 1.5e-50 172.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Complex1_51K PF01512.12 KLO18993.1 - 0.076 12.7 0.0 0.13 12.0 0.0 1.3 1 0 0 1 1 1 0 Respiratory-chain NADH dehydrogenase 51 Kd subunit UAA PF08449.6 KLO18995.1 - 0.051 12.4 0.1 0.053 12.4 0.1 1.1 1 0 0 1 1 1 0 UAA transporter family ABC_membrane PF00664.18 KLO18997.1 - 2.3e-47 161.7 26.9 1.7e-27 96.5 4.4 3.2 3 1 0 3 3 3 2 ABC transporter transmembrane region ABC_tran PF00005.22 KLO18997.1 - 2.9e-47 160.4 0.0 1.1e-28 100.3 0.0 2.6 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 KLO18997.1 - 1.3e-07 31.9 0.0 0.016 15.1 0.0 4.2 2 2 0 3 3 3 1 AAA domain SMC_N PF02463.14 KLO18997.1 - 3.9e-07 29.5 0.0 8.4e-05 21.8 0.0 3.0 2 2 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_25 PF13481.1 KLO18997.1 - 1.1e-06 28.2 0.1 0.0082 15.5 0.0 2.8 2 0 0 2 2 2 2 AAA domain T2SE PF00437.15 KLO18997.1 - 1.2e-05 24.3 0.2 0.084 11.7 0.0 2.4 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_29 PF13555.1 KLO18997.1 - 0.00013 21.4 0.3 0.14 11.7 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.1 KLO18997.1 - 0.00091 19.6 1.3 1.3 9.3 0.0 3.3 3 0 0 3 3 3 1 AAA domain AAA_10 PF12846.2 KLO18997.1 - 0.0014 18.1 0.0 1.4 8.3 0.0 2.5 2 0 0 2 2 2 2 AAA-like domain AAA_19 PF13245.1 KLO18997.1 - 0.013 15.2 0.1 1.5 8.6 0.0 2.9 2 0 0 2 2 2 0 Part of AAA domain AAA_16 PF13191.1 KLO18997.1 - 0.017 15.0 2.9 5.9 6.8 0.0 3.3 2 1 0 2 2 2 0 AAA ATPase domain AAA_22 PF13401.1 KLO18997.1 - 0.017 15.2 0.1 26 4.9 0.0 3.5 3 0 0 3 3 3 0 AAA domain DUF87 PF01935.12 KLO18997.1 - 0.022 14.5 1.4 0.026 14.3 0.0 1.8 2 0 0 2 2 1 0 Domain of unknown function DUF87 NACHT PF05729.7 KLO18997.1 - 0.022 14.3 2.1 5 6.7 0.0 3.4 3 0 0 3 3 3 0 NACHT domain Arch_ATPase PF01637.13 KLO18997.1 - 0.063 12.9 0.0 0.89 9.1 0.0 2.4 2 0 0 2 2 2 0 Archaeal ATPase AAA_17 PF13207.1 KLO18997.1 - 0.065 14.0 0.1 13 6.6 0.0 3.3 3 0 0 3 3 2 0 AAA domain AAA_18 PF13238.1 KLO18997.1 - 0.083 13.1 0.1 18 5.6 0.0 2.9 2 0 0 2 2 2 0 AAA domain MobB PF03205.9 KLO18997.1 - 0.099 12.3 0.1 6 6.5 0.0 2.6 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B Adeno_IVa2 PF02456.10 KLO18997.1 - 0.27 9.8 0.1 0.77 8.3 0.0 1.6 2 0 0 2 2 2 0 Adenovirus IVa2 protein DUF258 PF03193.11 KLO18997.1 - 0.36 10.0 0.0 15 4.6 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function, DUF258 Pkinase PF00069.20 KLO18998.1 - 2.6e-54 184.1 0.0 4.3e-38 130.9 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 KLO18998.1 - 7.8e-49 166.0 0.0 4.7e-38 130.7 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 KLO18998.1 - 0.00031 19.8 0.0 0.00067 18.7 0.0 1.5 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 KLO18998.1 - 0.0064 16.2 0.4 0.034 13.8 0.0 2.2 2 0 0 2 2 2 1 Phosphotransferase enzyme family WD40 PF00400.27 KLO18999.1 - 1.2e-63 208.8 23.9 1.5e-10 40.5 0.1 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat eIF2A PF08662.6 KLO18999.1 - 1.1e-10 41.5 0.4 0.00024 20.8 0.1 3.7 1 1 2 4 4 4 2 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 KLO18999.1 - 1.3e-07 30.1 8.0 0.02 13.0 0.1 4.5 1 1 4 5 5 5 4 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.11 KLO18999.1 - 6.8e-05 21.3 0.1 0.00045 18.6 0.0 2.2 2 1 0 2 2 2 1 Cytochrome D1 heme domain CDtoxinA PF03498.9 KLO18999.1 - 0.0015 17.9 1.6 0.044 13.1 0.4 2.8 1 1 2 3 3 3 1 Cytolethal distending toxin A/C family DUF1513 PF07433.6 KLO18999.1 - 0.0029 16.5 1.1 0.53 9.1 0.0 3.7 2 1 1 4 4 4 1 Protein of unknown function (DUF1513) Nucleoporin_N PF08801.6 KLO18999.1 - 0.024 13.4 6.7 0.046 12.4 1.3 2.8 1 1 2 3 3 3 0 Nup133 N terminal like Pectate_lyase22 PF14583.1 KLO18999.1 - 0.029 12.8 0.0 0.11 10.9 0.0 1.8 2 0 0 2 2 2 0 Oligogalacturonate lyase PD40 PF07676.7 KLO18999.1 - 0.097 12.3 0.0 48 3.7 0.0 3.4 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat YhfZ_C PF14503.1 KLO18999.1 - 0.14 11.4 0.0 0.28 10.5 0.0 1.4 1 0 0 1 1 1 0 YhfZ C-terminal domain MAGP PF05507.6 KLO18999.1 - 0.65 9.7 6.7 9.7 6.0 0.1 2.3 2 0 0 2 2 2 0 Microfibril-associated glycoprotein (MAGP) Pkinase_Tyr PF07714.12 KLO19000.1 - 9.2e-47 159.2 0.0 1.3e-46 158.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 KLO19000.1 - 1.6e-46 158.5 0.0 2.6e-46 157.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.1 KLO19000.1 - 2e-05 23.7 0.0 3.1e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 Kinase-like zf-C2HC_2 PF13913.1 KLO19000.1 - 2.1 8.0 12.4 0.064 12.9 1.0 2.8 3 0 0 3 3 3 0 zinc-finger of a C2HC-type Glyco_hydro_92 PF07971.7 KLO19001.1 - 5.7e-147 490.3 1.0 7e-147 490.0 0.7 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 Acetyltransf_1 PF00583.19 KLO19001.1 - 0.0058 16.6 0.0 0.013 15.5 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Pkinase PF00069.20 KLO19003.1 - 1.4e-29 103.0 0.0 1.7e-29 102.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KLO19003.1 - 2.8e-23 82.3 0.0 3.5e-23 82.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.17 KLO19003.1 - 0.00032 20.0 0.0 0.001 18.4 0.0 1.7 2 0 0 2 2 2 1 RIO1 family Kdo PF06293.9 KLO19003.1 - 0.032 13.2 0.0 0.054 12.5 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KLO19003.1 - 0.064 12.9 0.0 0.095 12.4 0.0 1.6 1 1 0 1 1 1 0 Phosphotransferase enzyme family Kinase-like PF14531.1 KLO19003.1 - 0.11 11.3 0.0 0.17 10.8 0.0 1.2 1 0 0 1 1 1 0 Kinase-like Kdo PF06293.9 KLO19004.1 - 0.012 14.6 0.1 1.3 8.0 0.0 2.3 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Thioredoxin_3 PF13192.1 KLO19004.1 - 0.034 13.9 0.2 0.073 12.8 0.1 1.5 1 0 0 1 1 1 0 Thioredoxin domain FG-GAP PF01839.18 KLO19004.1 - 0.048 13.3 0.9 0.12 12.1 0.6 1.6 1 0 0 1 1 1 0 FG-GAP repeat Pkinase PF00069.20 KLO19005.1 - 0.0011 18.1 0.1 0.0042 16.2 0.0 1.9 2 0 0 2 2 2 1 Protein kinase domain Kdo PF06293.9 KLO19005.1 - 0.016 14.2 0.4 2.8 6.9 0.1 2.7 3 0 0 3 3 3 0 Lipopolysaccharide kinase (Kdo/WaaP) family Thioredoxin_3 PF13192.1 KLO19005.1 - 0.02 14.6 0.1 0.083 12.7 0.0 2.0 2 0 0 2 2 2 0 Thioredoxin domain Mpp10 PF04006.7 KLO19005.1 - 0.021 13.1 16.7 0.0041 15.5 8.1 1.9 2 0 0 2 2 2 0 Mpp10 protein Nop14 PF04147.7 KLO19005.1 - 0.1 10.5 20.6 0.16 9.8 14.3 1.2 1 0 0 1 1 1 0 Nop14-like family DUF2201_N PF13203.1 KLO19005.1 - 0.12 11.5 2.3 0.25 10.5 1.6 1.5 1 0 0 1 1 1 0 Putative metallopeptidase domain CENP-T PF15511.1 KLO19005.1 - 0.15 11.3 11.6 0.27 10.4 8.1 1.4 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T DUF1510 PF07423.6 KLO19005.1 - 0.2 11.0 13.4 0.43 9.9 9.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Ycf1 PF05758.7 KLO19005.1 - 0.22 9.1 3.7 0.32 8.6 2.6 1.2 1 0 0 1 1 1 0 Ycf1 CDC45 PF02724.9 KLO19005.1 - 0.28 9.1 10.1 0.52 8.2 7.0 1.3 1 0 0 1 1 1 0 CDC45-like protein CobT PF06213.7 KLO19005.1 - 0.96 8.5 21.2 0.06 12.4 11.1 1.5 2 0 0 2 2 2 0 Cobalamin biosynthesis protein CobT RNA_pol_Rpc4 PF05132.9 KLO19005.1 - 2.6 8.0 9.7 8.3 6.3 6.7 1.8 1 0 0 1 1 1 0 RNA polymerase III RPC4 TFIIF_alpha PF05793.7 KLO19005.1 - 5.6 5.2 21.5 8.5 4.6 14.9 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Merozoite_SPAM PF07133.6 KLO19005.1 - 7.5 6.4 33.3 17 5.2 23.1 1.5 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) Paf1 PF03985.8 KLO19005.1 - 8.2 5.0 23.6 13 4.3 16.4 1.2 1 0 0 1 1 1 0 Paf1 RR_TM4-6 PF06459.7 KLO19005.1 - 8.4 6.1 14.9 17 5.2 10.3 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 FGGY_C PF02782.11 KLO19006.1 - 1.6e-61 207.3 1.4 2.5e-61 206.7 1.0 1.3 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.16 KLO19006.1 - 2e-61 207.4 0.1 1.3e-59 201.5 0.0 2.2 1 1 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain Glyco_hydro_47 PF01532.15 KLO19007.1 - 3.1e-133 444.7 0.0 3.5e-133 444.5 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 DUF2909 PF11137.3 KLO19007.1 - 0.11 12.1 0.2 11 5.8 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2909) zf-MYND PF01753.13 KLO19008.1 - 1e-08 34.8 9.5 1e-08 34.8 6.6 2.2 2 0 0 2 2 2 1 MYND finger DUF869 PF05911.6 KLO19009.1 - 8.4e-05 21.0 4.3 9.8e-05 20.7 3.0 1.0 1 0 0 1 1 1 1 Plant protein of unknown function (DUF869) Filament PF00038.16 KLO19009.1 - 0.0074 15.7 8.8 0.011 15.2 6.1 1.2 1 0 0 1 1 1 1 Intermediate filament protein Tropomyosin_1 PF12718.2 KLO19009.1 - 0.0085 15.9 12.8 0.013 15.3 8.9 1.2 1 0 0 1 1 1 1 Tropomyosin like Laminin_II PF06009.7 KLO19009.1 - 0.011 15.4 6.0 0.02 14.6 3.8 1.7 1 1 0 1 1 1 0 Laminin Domain II EzrA PF06160.7 KLO19009.1 - 0.011 13.9 6.3 0.016 13.4 4.4 1.2 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA CENP-F_leu_zip PF10473.4 KLO19009.1 - 0.071 12.9 18.2 0.31 10.8 5.8 2.1 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 ERM PF00769.14 KLO19009.1 - 0.12 11.8 13.3 0.19 11.2 9.2 1.2 1 0 0 1 1 1 0 Ezrin/radixin/moesin family K-box PF01486.12 KLO19009.1 - 0.21 11.4 5.9 0.49 10.2 4.1 1.6 1 1 0 1 1 1 0 K-box region Spc7 PF08317.6 KLO19009.1 - 0.41 9.2 9.0 0.57 8.7 6.2 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein APG6 PF04111.7 KLO19009.1 - 0.44 9.5 14.3 1.5 7.7 8.4 2.0 1 1 1 2 2 2 0 Autophagy protein Apg6 Sigma54_CBD PF04963.8 KLO19009.1 - 0.46 9.8 3.9 0.7 9.2 2.7 1.2 1 0 0 1 1 1 0 Sigma-54 factor, core binding domain DUF842 PF05811.8 KLO19009.1 - 0.68 9.3 4.9 2.6 7.5 0.3 2.2 1 1 1 2 2 2 0 Eukaryotic protein of unknown function (DUF842) DMPK_coil PF08826.5 KLO19009.1 - 1.1 9.1 10.2 0.22 11.4 2.6 2.8 2 1 1 3 3 3 0 DMPK coiled coil domain like IncA PF04156.9 KLO19009.1 - 1.8 8.1 14.6 2.3 7.7 9.6 1.6 1 1 0 1 1 1 0 IncA protein Rootletin PF15035.1 KLO19009.1 - 3.2 7.6 12.9 7.9 6.4 8.9 1.6 1 1 1 2 2 2 0 Ciliary rootlet component, centrosome cohesion DUF1664 PF07889.7 KLO19009.1 - 3.3 7.5 5.9 7.5 6.3 1.0 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) HrpB7 PF09486.5 KLO19009.1 - 5.3 6.9 15.0 0.39 10.6 2.4 2.2 1 1 0 1 1 1 0 Bacterial type III secretion protein (HrpB7) Spc24 PF08286.6 KLO19009.1 - 6.7 6.4 7.3 6 6.5 1.6 2.2 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 DUF972 PF06156.8 KLO19009.1 - 7.5 6.9 10.5 3.5 8.0 3.4 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF972) Prefoldin_2 PF01920.15 KLO19009.1 - 9 6.1 10.6 17 5.1 1.6 2.8 1 1 2 3 3 3 0 Prefoldin subunit DUF2408 PF10303.4 KLO19010.1 - 6.4e-62 207.5 0.7 6.3e-35 120.2 0.0 4.5 2 2 2 4 4 4 4 Protein of unknown function (DUF2408) Reo_sigmaC PF04582.7 KLO19010.1 - 0.0071 15.5 0.1 0.13 11.4 0.0 2.5 3 0 0 3 3 3 1 Reovirus sigma C capsid protein DUF1664 PF07889.7 KLO19010.1 - 0.046 13.5 0.6 1.2 8.8 0.1 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) DUF4446 PF14584.1 KLO19010.1 - 1.4 8.7 0.0 1.4 8.7 0.0 3.2 4 1 1 5 5 5 0 Protein of unknown function (DUF4446) Tropomyosin_1 PF12718.2 KLO19011.1 - 1.1e-41 142.0 27.5 1.3e-41 141.8 19.0 1.1 1 0 0 1 1 1 1 Tropomyosin like Tropomyosin PF00261.15 KLO19011.1 - 8.7e-11 41.3 26.8 8.3e-07 28.3 10.3 2.7 1 1 1 2 2 2 2 Tropomyosin ERM PF00769.14 KLO19011.1 - 0.00094 18.7 27.3 0.0025 17.3 13.6 2.1 1 1 1 2 2 2 2 Ezrin/radixin/moesin family MscS_porin PF12795.2 KLO19011.1 - 0.0019 17.5 17.2 0.1 11.8 4.7 2.1 1 1 1 2 2 2 2 Mechanosensitive ion channel porin domain DUF3450 PF11932.3 KLO19011.1 - 0.002 17.4 14.3 0.028 13.7 3.9 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF3450) GAS PF13851.1 KLO19011.1 - 0.0025 17.0 23.3 0.063 12.4 7.1 2.1 1 1 1 2 2 2 2 Growth-arrest specific micro-tubule binding ADIP PF11559.3 KLO19011.1 - 0.0089 15.9 23.8 0.056 13.3 7.6 2.1 1 1 1 2 2 2 2 Afadin- and alpha -actinin-Binding Reo_sigmaC PF04582.7 KLO19011.1 - 0.011 14.9 1.4 0.029 13.5 0.5 1.6 1 1 0 1 1 1 0 Reovirus sigma C capsid protein BRE1 PF08647.6 KLO19011.1 - 0.011 15.6 5.6 0.011 15.6 3.9 2.2 1 1 1 2 2 2 0 BRE1 E3 ubiquitin ligase Imm15 PF15590.1 KLO19011.1 - 0.015 14.3 0.2 0.045 12.8 0.2 1.8 1 0 0 1 1 1 0 Immunity protein 15 DUF641 PF04859.7 KLO19011.1 - 0.02 14.6 15.4 0.029 14.1 1.9 2.3 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) DUF3287 PF11690.3 KLO19011.1 - 0.021 14.8 1.4 0.021 14.8 1.0 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF3287) CENP-F_leu_zip PF10473.4 KLO19011.1 - 0.021 14.6 4.8 0.021 14.6 3.3 2.5 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 IncA PF04156.9 KLO19011.1 - 0.025 14.1 23.6 0.34 10.4 3.5 2.0 1 1 1 2 2 2 0 IncA protein WEMBL PF05701.6 KLO19011.1 - 0.026 13.0 27.1 0.048 12.1 18.8 1.4 1 1 0 1 1 1 0 Weak chloroplast movement under blue light Macoilin PF09726.4 KLO19011.1 - 0.028 12.7 20.6 0.28 9.4 5.5 2.0 1 1 1 2 2 2 0 Transmembrane protein TMF_TATA_bd PF12325.3 KLO19011.1 - 0.035 13.8 19.7 0.6 9.8 8.2 2.4 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding Myosin_tail_1 PF01576.14 KLO19011.1 - 0.039 11.6 28.6 0.049 11.3 19.8 1.1 1 0 0 1 1 1 0 Myosin tail Laminin_II PF06009.7 KLO19011.1 - 0.043 13.5 13.2 0.93 9.2 1.7 2.5 1 1 1 2 2 2 0 Laminin Domain II SlyX PF04102.7 KLO19011.1 - 0.051 13.9 12.3 0.32 11.4 1.3 2.9 2 2 1 3 3 2 0 SlyX DUF4200 PF13863.1 KLO19011.1 - 0.093 12.6 25.1 0.45 10.4 7.3 2.6 1 1 0 2 2 2 0 Domain of unknown function (DUF4200) Spectrin PF00435.16 KLO19011.1 - 0.094 13.0 18.6 0.78 10.0 5.7 2.8 1 1 1 2 2 2 0 Spectrin repeat TPR_MLP1_2 PF07926.7 KLO19011.1 - 0.15 11.8 25.1 0.14 11.8 3.9 3.2 1 1 2 3 3 3 0 TPR/MLP1/MLP2-like protein Spc7 PF08317.6 KLO19011.1 - 0.18 10.4 23.2 0.14 10.7 7.1 2.0 1 1 1 2 2 2 0 Spc7 kinetochore protein ATG16 PF08614.6 KLO19011.1 - 0.21 11.3 22.5 1.3 8.8 5.4 2.3 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) DUF3584 PF12128.3 KLO19011.1 - 0.23 8.7 23.6 0.075 10.3 12.0 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) AAA_13 PF13166.1 KLO19011.1 - 0.27 9.6 18.9 0.16 10.3 4.0 2.0 1 1 1 2 2 2 0 AAA domain Tup_N PF08581.5 KLO19011.1 - 0.39 10.9 12.4 0.17 12.1 1.2 2.5 1 1 2 3 3 3 0 Tup N-terminal APG6 PF04111.7 KLO19011.1 - 0.39 9.6 27.7 0.19 10.7 15.5 1.9 1 1 1 2 2 2 0 Autophagy protein Apg6 DUF919 PF06034.6 KLO19011.1 - 0.4 10.3 6.9 0.19 11.3 0.2 3.0 3 0 0 3 3 2 0 Nucleopolyhedrovirus protein of unknown function (DUF919) LppC PF04348.8 KLO19011.1 - 0.49 8.8 9.2 0.58 8.6 6.4 1.0 1 0 0 1 1 1 0 LppC putative lipoprotein Nup54 PF13874.1 KLO19011.1 - 0.51 9.9 14.4 0.35 10.5 4.2 2.3 1 1 1 2 2 2 0 Nucleoporin complex subunit 54 DUF948 PF06103.6 KLO19011.1 - 0.52 10.2 5.7 2.9 7.8 0.2 2.4 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Laminin_I PF06008.9 KLO19011.1 - 0.57 9.4 21.2 1.1 8.5 10.5 2.2 1 1 1 2 2 2 0 Laminin Domain I DUF745 PF05335.8 KLO19011.1 - 0.68 9.4 17.4 2.9 7.3 12.1 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF745) PspA_IM30 PF04012.7 KLO19011.1 - 0.72 9.1 24.1 8 5.7 16.7 2.2 1 1 0 1 1 1 0 PspA/IM30 family Cep57_CLD_2 PF14197.1 KLO19011.1 - 0.81 9.6 26.7 1.4 8.8 0.5 3.1 1 1 2 3 3 3 0 Centrosome localisation domain of PPC89 Flagellin_C PF00700.16 KLO19011.1 - 0.85 9.8 4.0 8.8 6.5 0.1 3.0 1 1 0 2 2 2 0 Bacterial flagellin C-terminal helical region CCDC155 PF14662.1 KLO19011.1 - 0.95 9.0 25.4 0.52 9.8 8.4 2.1 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 RmuC PF02646.11 KLO19011.1 - 1 8.1 11.4 1.5 7.5 1.4 2.3 1 1 2 3 3 3 0 RmuC family She9_MDM33 PF05546.6 KLO19011.1 - 1 8.8 12.5 0.42 10.1 1.4 2.9 1 1 2 3 3 3 0 She9 / Mdm33 family Lzipper-MIP1 PF14389.1 KLO19011.1 - 1.3 9.2 17.8 0.39 10.8 4.9 3.4 2 2 1 3 3 3 0 Leucine-zipper of ternary complex factor MIP1 DUF4201 PF13870.1 KLO19011.1 - 1.3 8.4 21.2 2.2 7.6 5.4 2.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4201) TMCO5 PF14992.1 KLO19011.1 - 1.9 7.5 20.7 1.7 7.7 6.9 2.1 1 1 1 2 2 2 0 TMCO5 family Fib_alpha PF08702.5 KLO19011.1 - 2 8.5 10.7 5 7.2 2.2 2.4 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family OmpH PF03938.9 KLO19011.1 - 2.1 8.2 23.1 5.2 6.9 5.2 2.2 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) V_ATPase_I PF01496.14 KLO19011.1 - 2.3 5.9 15.4 1.9 6.2 9.4 1.6 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family Prefoldin_2 PF01920.15 KLO19011.1 - 2.6 7.8 23.4 4.1 7.2 3.6 4.0 1 1 1 2 2 2 0 Prefoldin subunit Fmp27_WPPW PF10359.4 KLO19011.1 - 2.6 6.3 17.7 2 6.7 4.5 2.0 1 1 1 2 2 2 0 RNA pol II promoter Fmp27 protein domain BLOC1_2 PF10046.4 KLO19011.1 - 2.6 8.2 13.3 1.9 8.6 1.7 2.7 1 1 1 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Occludin_ELL PF07303.8 KLO19011.1 - 2.7 8.7 12.0 26 5.5 3.0 3.3 1 1 2 3 3 3 0 Occludin homology domain COG2 PF06148.6 KLO19011.1 - 2.7 7.8 11.6 2 8.2 0.8 2.6 1 1 2 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF1664 PF07889.7 KLO19011.1 - 2.9 7.7 10.9 2.2 8.0 1.7 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Mnd1 PF03962.10 KLO19011.1 - 3 7.4 22.1 1.2 8.8 3.7 2.2 1 1 1 2 2 2 0 Mnd1 family Acyl-CoA_dh_2 PF08028.6 KLO19011.1 - 3.1 8.0 6.1 1 9.6 1.4 2.1 1 1 1 2 2 2 0 Acyl-CoA dehydrogenase, C-terminal domain Striatin PF08232.7 KLO19011.1 - 4.1 7.7 18.7 3.5 7.9 5.3 2.2 1 1 1 2 2 2 0 Striatin family Snapin_Pallidin PF14712.1 KLO19011.1 - 4.2 7.7 13.8 3.6 7.9 2.3 2.9 1 1 0 2 2 2 0 Snapin/Pallidin DUF812 PF05667.6 KLO19011.1 - 4.8 5.5 21.0 3.6 5.9 6.7 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF812) CDC37_N PF03234.9 KLO19011.1 - 4.9 7.4 16.4 8.4 6.6 11.4 1.4 1 1 0 1 1 1 0 Cdc37 N terminal kinase binding NPV_P10 PF05531.7 KLO19011.1 - 5.6 7.2 9.5 6 7.1 0.8 3.4 2 2 1 3 3 3 0 Nucleopolyhedrovirus P10 protein Prefoldin PF02996.12 KLO19011.1 - 5.8 6.5 16.4 0.16 11.6 1.3 3.5 1 1 2 4 4 4 0 Prefoldin subunit Adeno_PIX PF03955.9 KLO19011.1 - 6 7.4 9.8 9.5 6.7 0.7 2.7 1 1 2 3 3 3 0 Adenovirus hexon-associated protein (IX) DUF3166 PF11365.3 KLO19011.1 - 7.3 7.1 14.5 51 4.4 1.6 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF3166) Med4 PF10018.4 KLO19011.1 - 8.3 5.7 18.8 6.9 6.0 3.8 3.0 1 1 1 2 2 2 0 Vitamin-D-receptor interacting Mediator subunit 4 Uds1 PF15456.1 KLO19011.1 - 8.4 6.4 20.2 2.2e+02 1.8 14.0 2.8 1 1 0 1 1 1 0 Up-regulated During Septation SelR PF01641.13 KLO19012.1 - 7e-50 167.8 0.1 8.1e-50 167.6 0.1 1.0 1 0 0 1 1 1 1 SelR domain DZR PF12773.2 KLO19012.1 - 0.14 12.0 3.3 2.7 7.8 2.3 2.3 1 1 0 1 1 1 0 Double zinc ribbon DnaJ_CXXCXGXG PF00684.14 KLO19012.1 - 0.25 11.4 3.2 0.32 11.0 0.3 2.3 2 1 0 2 2 2 0 DnaJ central domain Tim44 PF04280.10 KLO19014.1 - 4e-31 107.9 0.5 9.7e-31 106.7 0.4 1.7 1 0 0 1 1 1 1 Tim44-like domain HTH_12 PF08461.5 KLO19014.1 - 0.065 12.9 0.1 0.21 11.3 0.0 1.8 1 0 0 1 1 1 0 Ribonuclease R winged-helix domain Paralemmin PF03285.10 KLO19014.1 - 0.095 12.1 4.7 0.15 11.4 3.3 1.3 1 0 0 1 1 1 0 Paralemmin Herpes_UL25 PF01499.11 KLO19014.1 - 0.75 8.0 5.8 2.2 6.4 3.0 2.1 1 1 0 2 2 2 0 Herpesvirus UL25 family Cyto_heme_lyase PF01265.12 KLO19015.1 - 4.8e-63 213.1 0.0 5.5e-63 212.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome c/c1 heme lyase CactinC_cactus PF09732.4 KLO19018.1 - 0.0042 16.6 0.1 0.0059 16.1 0.0 1.2 1 0 0 1 1 1 1 Cactus-binding C-terminus of cactin protein DNA_ligase_A_C PF04679.10 KLO19018.1 - 0.036 14.4 0.1 0.14 12.5 0.1 1.8 2 0 0 2 2 2 0 ATP dependent DNA ligase C terminal region VRR_NUC PF08774.6 KLO19021.1 - 0.044 13.8 0.0 0.098 12.6 0.0 1.6 1 0 0 1 1 1 0 VRR-NUC domain DDE_3 PF13358.1 KLO19023.1 - 8e-08 32.1 0.0 8.5e-08 32.0 0.0 1.0 1 0 0 1 1 1 1 DDE superfamily endonuclease AT_hook PF02178.14 KLO19024.1 - 0.058 13.0 3.4 0.33 10.7 2.3 2.5 1 0 0 1 1 1 0 AT hook motif IZUMO PF15005.1 KLO19025.1 - 0.1 12.6 0.4 0.33 10.9 0.2 1.7 1 1 0 1 1 1 0 Izumo sperm-egg fusion Mito_fiss_reg PF05308.6 KLO19026.1 - 5.2 6.3 14.7 0.021 14.2 2.6 2.1 1 1 0 2 2 2 0 Mitochondrial fission regulator UAA PF08449.6 KLO19029.1 - 3.8e-15 55.6 16.6 5e-15 55.1 11.5 1.1 1 0 0 1 1 1 1 UAA transporter family TPT PF03151.11 KLO19029.1 - 8.6e-10 38.4 5.0 8.6e-10 38.4 3.4 2.8 2 1 0 2 2 2 1 Triose-phosphate Transporter family DUF4405 PF14358.1 KLO19029.1 - 3.3 7.9 8.9 0.8 9.8 2.3 2.8 2 1 0 2 2 2 0 Domain of unknown function (DUF4405) CPSase_L_D2 PF02786.12 KLO19030.1 - 4.8e-80 267.7 0.1 1.6e-79 266.0 0.2 1.8 2 0 0 2 2 2 1 Carbamoyl-phosphate synthase L chain, ATP binding domain PYC_OADA PF02436.13 KLO19030.1 - 7.6e-69 231.0 0.0 1.5e-68 230.1 0.0 1.5 1 0 0 1 1 1 1 Conserved carboxylase domain CPSase_L_chain PF00289.17 KLO19030.1 - 4.3e-37 126.5 0.1 1.2e-36 125.1 0.0 1.8 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, N-terminal domain Biotin_carb_C PF02785.14 KLO19030.1 - 1.2e-30 105.5 0.0 4.4e-30 103.8 0.0 2.0 2 0 0 2 2 2 1 Biotin carboxylase C-terminal domain HMGL-like PF00682.14 KLO19030.1 - 4.9e-30 104.9 0.1 2.1e-29 102.8 0.0 2.1 2 0 0 2 2 2 1 HMGL-like ATP-grasp_4 PF13535.1 KLO19030.1 - 1.6e-17 63.8 0.1 3.1e-17 62.9 0.1 1.5 1 0 0 1 1 1 1 ATP-grasp domain Biotin_lipoyl PF00364.17 KLO19030.1 - 3.3e-17 61.8 5.3 3.3e-17 61.8 3.6 2.1 2 0 0 2 2 2 1 Biotin-requiring enzyme ATPgrasp_Ter PF15632.1 KLO19030.1 - 3.4e-16 58.9 0.1 3e-15 55.7 0.0 2.2 2 1 0 2 2 2 1 ATP-grasp in the biosynthetic pathway with Ter operon Biotin_lipoyl_2 PF13533.1 KLO19030.1 - 3.3e-13 49.0 10.7 5.1e-08 32.4 0.4 2.9 3 0 0 3 3 2 2 Biotin-lipoyl like Dala_Dala_lig_C PF07478.8 KLO19030.1 - 6e-11 42.1 0.0 1.3e-10 40.9 0.0 1.5 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus HlyD PF00529.15 KLO19030.1 - 1.5e-08 34.3 5.6 0.00038 19.8 0.4 2.5 2 0 0 2 2 2 2 HlyD family secretion protein ATP-grasp PF02222.17 KLO19030.1 - 2.3e-07 30.3 0.1 5.7e-07 29.0 0.1 1.6 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_3 PF02655.9 KLO19030.1 - 4.9e-06 26.4 0.0 1.1e-05 25.3 0.0 1.6 1 0 0 1 1 1 1 ATP-grasp domain HlyD_3 PF13437.1 KLO19030.1 - 4.6e-05 23.6 5.1 0.098 13.0 0.1 3.3 4 0 0 4 4 2 2 HlyD family secretion protein RimK PF08443.6 KLO19030.1 - 5.4e-05 22.7 0.0 0.00013 21.4 0.0 1.7 1 0 0 1 1 1 1 RimK-like ATP-grasp domain NQRA PF05896.6 KLO19030.1 - 0.0016 17.6 0.5 0.005 16.0 0.4 1.8 1 0 0 1 1 1 1 Na(+)-translocating NADH-quinone reductase subunit A (NQRA) HlyD_2 PF12700.2 KLO19030.1 - 0.004 16.3 1.9 0.055 12.6 0.2 2.1 1 1 1 2 2 2 1 HlyD family secretion protein GARS_A PF01071.14 KLO19030.1 - 0.013 15.0 1.0 0.021 14.3 0.0 1.8 2 0 0 2 2 2 0 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain GCV_H PF01597.14 KLO19030.1 - 0.048 13.3 5.1 0.083 12.5 0.8 2.6 1 1 1 2 2 2 0 Glycine cleavage H-protein DUF2118 PF09891.4 KLO19030.1 - 0.059 13.0 1.8 0.77 9.4 1.7 2.6 2 1 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2118) Biotin_lipoyl PF00364.17 KLO19031.1 - 9.4e-11 41.2 8.4 1.7e-10 40.3 5.8 1.5 1 1 0 1 1 1 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.1 KLO19031.1 - 5.5e-07 29.1 10.2 5.9e-05 22.6 1.4 2.1 1 1 1 2 2 2 2 Biotin-lipoyl like HlyD_3 PF13437.1 KLO19031.1 - 3.7e-06 27.2 5.2 0.0028 17.9 0.2 2.0 1 1 1 2 2 2 2 HlyD family secretion protein HlyD_2 PF12700.2 KLO19031.1 - 5.1e-05 22.5 7.4 0.0025 17.0 0.3 2.0 1 1 1 2 2 2 2 HlyD family secretion protein RnfC_N PF13375.1 KLO19031.1 - 0.0027 17.4 8.9 0.0094 15.6 3.0 2.1 1 1 1 2 2 2 2 RnfC Barrel sandwich hybrid domain NQRA PF05896.6 KLO19031.1 - 0.016 14.3 3.4 0.04 13.1 0.6 2.0 1 1 1 2 2 2 0 Na(+)-translocating NADH-quinone reductase subunit A (NQRA) Peptidase_M23 PF01551.17 KLO19031.1 - 0.026 14.5 5.7 0.049 13.6 3.9 1.5 1 1 0 1 1 1 0 Peptidase family M23 HlyD PF00529.15 KLO19031.1 - 0.14 11.4 9.6 0.2 10.9 0.6 2.0 2 0 0 2 2 2 0 HlyD family secretion protein Biotin_lipoyl PF00364.17 KLO19032.1 - 4.8e-06 26.1 4.6 0.002 17.6 0.6 2.7 2 1 0 2 2 2 2 Biotin-requiring enzyme HlyD_2 PF12700.2 KLO19032.1 - 0.0033 16.6 0.5 0.055 12.6 0.0 2.1 1 1 1 2 2 2 2 HlyD family secretion protein NMO PF03060.10 KLO19033.1 - 2.8e-52 177.8 2.8 3.9e-52 177.4 1.9 1.2 1 0 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.20 KLO19033.1 - 1.7e-06 27.1 0.1 0.0098 14.8 0.0 2.5 3 0 0 3 3 3 2 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.13 KLO19033.1 - 6.4e-06 25.2 2.8 3.2e-05 22.9 0.4 2.2 2 0 0 2 2 2 1 FMN-dependent dehydrogenase DHO_dh PF01180.16 KLO19033.1 - 0.026 13.4 0.0 0.044 12.7 0.0 1.3 1 0 0 1 1 1 0 Dihydroorotate dehydrogenase His_biosynth PF00977.16 KLO19033.1 - 0.031 13.5 0.0 0.062 12.5 0.0 1.5 1 0 0 1 1 1 0 Histidine biosynthesis protein LSM PF01423.17 KLO19034.1 - 9.4e-16 57.1 0.0 1.2e-15 56.8 0.0 1.1 1 0 0 1 1 1 1 LSM domain zf-BED PF02892.10 KLO19037.1 - 0.098 12.4 0.3 0.3 10.8 0.2 1.8 1 0 0 1 1 1 0 BED zinc finger zf-C4 PF00105.13 KLO19043.1 - 0.11 12.7 0.7 0.11 12.7 0.5 2.5 3 0 0 3 3 3 0 Zinc finger, C4 type (two domains) DUF3040 PF11239.3 KLO19045.1 - 0.099 12.7 0.0 0.21 11.6 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3040) GlgS PF08971.6 KLO19045.1 - 0.11 12.5 1.6 0.31 10.9 0.1 2.4 2 1 1 3 3 3 0 Glycogen synthesis protein SHR3_chaperone PF08229.6 KLO19048.1 - 1.4e-33 115.5 0.1 1.5e-33 115.3 0.0 1.0 1 0 0 1 1 1 1 ER membrane protein SH3 F-box-like PF12937.2 KLO19049.1 - 0.021 14.5 0.0 0.072 12.8 0.0 2.0 1 0 0 1 1 1 0 F-box-like TPR_11 PF13414.1 KLO19051.1 - 1.2e-15 56.9 0.1 5.2e-10 38.8 0.0 2.3 2 0 0 2 2 2 2 TPR repeat TPR_2 PF07719.12 KLO19051.1 - 1e-08 34.3 0.2 0.0012 18.5 0.0 3.4 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_12 PF13424.1 KLO19051.1 - 2.1e-08 33.9 0.1 0.00015 21.6 0.1 2.3 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.23 KLO19051.1 - 3.7e-08 32.6 0.6 0.0022 17.5 0.1 3.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.1 KLO19051.1 - 2.8e-06 27.4 0.1 0.0011 19.4 0.0 2.9 3 0 0 3 3 2 1 Tetratricopeptide repeat TPR_16 PF13432.1 KLO19051.1 - 8.9e-05 23.0 0.1 0.0022 18.6 0.1 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.1 KLO19051.1 - 0.00031 21.0 0.8 0.0078 16.5 0.0 2.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.1 KLO19051.1 - 0.0013 18.3 0.4 0.49 10.3 0.0 3.0 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.1 KLO19051.1 - 0.0021 17.6 0.1 0.59 10.0 0.0 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_6 PF13174.1 KLO19051.1 - 0.013 15.9 0.1 5.5 7.6 0.0 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_9 PF13371.1 KLO19051.1 - 0.08 12.8 0.0 0.99 9.3 0.0 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_17 PF13431.1 KLO19051.1 - 0.1 12.8 0.0 26 5.3 0.0 3.6 4 0 0 4 4 3 0 Tetratricopeptide repeat DUF3856 PF12968.2 KLO19051.1 - 0.1 12.4 0.1 1.9 8.3 0.0 2.1 2 0 0 2 2 2 0 Domain of Unknown Function (DUF3856) Fis1_TPR_C PF14853.1 KLO19051.1 - 0.16 11.8 0.2 0.51 10.2 0.0 1.9 2 0 0 2 2 2 0 Fis1 C-terminal tetratricopeptide repeat NmrA PF05368.8 KLO19053.1 - 5.4e-28 97.8 0.0 7.3e-28 97.3 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 KLO19053.1 - 3.2e-06 27.2 0.0 6.2e-06 26.3 0.0 1.5 1 0 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 KLO19053.1 - 6.1e-05 21.8 0.0 8.8e-05 21.3 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Saccharop_dh PF03435.13 KLO19053.1 - 0.05 12.5 0.0 0.13 11.2 0.0 1.6 2 0 0 2 2 2 0 Saccharopine dehydrogenase Shikimate_DH PF01488.15 KLO19053.1 - 0.14 12.2 0.0 0.28 11.2 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase NmrA PF05368.8 KLO19054.1 - 1.9e-31 109.1 0.0 2.6e-31 108.6 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 KLO19054.1 - 1.3e-07 31.8 0.5 2.4e-07 30.9 0.3 1.5 1 1 0 1 1 1 1 NADH(P)-binding Saccharop_dh PF03435.13 KLO19054.1 - 9.9e-05 21.4 0.4 0.00032 19.7 0.2 1.7 2 0 0 2 2 2 1 Saccharopine dehydrogenase 3Beta_HSD PF01073.14 KLO19054.1 - 0.00033 19.4 0.1 0.00048 18.9 0.1 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family TrkA_N PF02254.13 KLO19054.1 - 0.00093 19.1 0.1 0.0014 18.5 0.1 1.3 1 0 0 1 1 1 1 TrkA-N domain NAD_binding_3 PF03447.11 KLO19054.1 - 0.0017 18.7 0.8 0.81 10.0 0.0 2.4 1 1 1 2 2 2 2 Homoserine dehydrogenase, NAD binding domain F420_oxidored PF03807.12 KLO19054.1 - 0.0036 17.6 0.8 0.013 15.9 0.3 2.1 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent Shikimate_DH PF01488.15 KLO19054.1 - 0.0089 16.1 0.0 0.015 15.4 0.0 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase TonB_C PF03544.9 KLO19054.1 - 0.046 13.9 0.3 0.1 12.8 0.0 1.6 2 0 0 2 2 2 0 Gram-negative bacterial TonB protein C-terminal NmrA PF05368.8 KLO19055.1 - 2.3e-25 89.2 0.0 6.8e-25 87.6 0.0 1.6 2 0 0 2 2 2 1 NmrA-like family NAD_binding_10 PF13460.1 KLO19055.1 - 7e-08 32.6 0.0 1.3e-07 31.7 0.0 1.5 2 0 0 2 2 2 1 NADH(P)-binding Saccharop_dh PF03435.13 KLO19055.1 - 0.00027 20.0 0.0 0.0029 16.6 0.1 2.0 2 0 0 2 2 2 1 Saccharopine dehydrogenase 3Beta_HSD PF01073.14 KLO19055.1 - 0.0018 17.0 0.0 0.0026 16.5 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family TrkA_N PF02254.13 KLO19055.1 - 0.041 13.8 0.1 0.075 13.0 0.1 1.4 1 0 0 1 1 1 0 TrkA-N domain CPSase_L_chain PF00289.17 KLO19055.1 - 0.12 12.4 0.0 0.28 11.3 0.0 1.6 1 0 0 1 1 1 0 Carbamoyl-phosphate synthase L chain, N-terminal domain RVT_1 PF00078.22 KLO19057.1 - 3.4e-09 36.3 0.0 1.1e-08 34.7 0.0 1.7 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Bromo_TP PF07524.8 KLO19057.1 - 0.15 11.8 0.9 1.1 9.0 0.0 2.7 3 0 0 3 3 3 0 Bromodomain associated DUF2183 PF09949.4 KLO19059.1 - 1.2e-25 89.3 0.0 3e-25 88.0 0.0 1.7 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2183) LNS2 PF08235.8 KLO19059.1 - 0.024 14.1 0.0 0.043 13.3 0.0 1.3 1 0 0 1 1 1 0 LNS2 (Lipin/Ned1/Smp2) DUF914 PF06027.7 KLO19060.1 - 2.9e-108 361.7 7.4 3.8e-108 361.2 5.1 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF914) UAA PF08449.6 KLO19060.1 - 0.0066 15.3 6.7 0.0093 14.9 4.6 1.3 1 1 0 1 1 1 1 UAA transporter family TPT PF03151.11 KLO19060.1 - 0.088 12.4 13.2 0.088 12.4 1.2 2.7 2 1 0 2 2 2 0 Triose-phosphate Transporter family DUF543 PF04418.7 KLO19060.1 - 0.37 10.7 0.0 0.37 10.7 0.0 2.6 4 0 0 4 4 4 0 Domain of unknown function (DUF543) EamA PF00892.15 KLO19060.1 - 6.5 6.8 25.5 0.35 10.9 5.2 3.2 2 1 1 3 3 3 0 EamA-like transporter family Ribosomal_S19 PF00203.16 KLO19061.1 - 1e-32 111.5 0.1 1.7e-32 110.8 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S19 Ribosomal_60s PF00428.14 KLO19062.1 - 1.7e-26 92.4 18.2 2e-26 92.2 12.6 1.0 1 0 0 1 1 1 1 60s Acidic ribosomal protein Sigma70_ner PF04546.8 KLO19062.1 - 0.058 13.0 3.0 0.081 12.5 2.1 1.2 1 0 0 1 1 1 0 Sigma-70, non-essential region ParA PF10609.4 KLO19064.1 - 1.8e-36 123.8 0.0 3.9e-36 122.7 0.0 1.5 1 0 0 1 1 1 1 ParA/MinD ATPase like CbiA PF01656.18 KLO19064.1 - 1.7e-12 47.1 0.0 2.6e-12 46.5 0.0 1.2 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain ArsA_ATPase PF02374.10 KLO19064.1 - 0.00018 20.6 0.2 0.0026 16.8 0.1 2.1 2 1 0 2 2 2 1 Anion-transporting ATPase AAA_25 PF13481.1 KLO19064.1 - 0.0012 18.2 0.0 0.0021 17.5 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_26 PF13500.1 KLO19064.1 - 0.0043 16.6 0.0 0.021 14.4 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_31 PF13614.1 KLO19064.1 - 0.0045 16.9 0.0 0.014 15.3 0.0 1.7 2 0 0 2 2 2 1 AAA domain Fer4_NifH PF00142.13 KLO19064.1 - 0.0071 15.5 0.0 3.7 6.6 0.2 3.1 2 2 1 3 3 3 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family DUF258 PF03193.11 KLO19064.1 - 0.051 12.7 0.0 0.097 11.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 YjeF_N PF03853.10 KLO19064.1 - 0.054 13.1 0.0 2.3 7.7 0.0 2.2 2 0 0 2 2 2 0 YjeF-related protein N-terminus VirE PF05272.6 KLO19064.1 - 0.057 12.8 0.0 0.09 12.2 0.0 1.2 1 0 0 1 1 1 0 Virulence-associated protein E YhjQ PF06564.7 KLO19064.1 - 0.13 11.6 0.1 0.21 10.9 0.1 1.5 1 1 0 1 1 1 0 YhjQ protein MipZ PF09140.6 KLO19064.1 - 0.14 11.2 0.0 0.66 9.0 0.0 2.0 1 1 0 1 1 1 0 ATPase MipZ RhoGAP PF00620.22 KLO19065.1 - 8.5e-38 129.3 0.1 2.1e-37 128.0 0.1 1.6 1 0 0 1 1 1 1 RhoGAP domain LIM PF00412.17 KLO19065.1 - 4.1e-24 84.3 39.0 3.8e-11 42.8 6.4 4.7 5 0 0 5 5 5 4 LIM domain KAP PF05804.7 KLO19065.1 - 0.028 12.3 0.2 0.042 11.7 0.1 1.1 1 0 0 1 1 1 0 Kinesin-associated protein (KAP) Ribosomal_60s PF00428.14 KLO19066.1 - 7.6e-08 32.6 16.9 1e-05 25.8 11.7 2.9 1 1 0 1 1 1 1 60s Acidic ribosomal protein BUD22 PF09073.5 KLO19066.1 - 0.039 13.0 0.6 0.044 12.8 0.4 1.0 1 0 0 1 1 1 0 BUD22 Fungal_trans PF04082.13 KLO19067.1 - 4.1e-12 45.5 0.2 4.1e-12 45.5 0.1 1.8 3 0 0 3 3 3 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KLO19067.1 - 9.9e-10 38.1 9.4 1.7e-09 37.4 6.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Med3 PF11593.3 KLO19067.1 - 0.26 10.4 2.9 0.48 9.6 2.0 1.4 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Pkinase PF00069.20 KLO19068.1 - 1.2e-70 237.6 0.0 1.6e-70 237.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KLO19068.1 - 4.8e-33 114.3 0.0 6.8e-33 113.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KLO19068.1 - 0.0096 14.9 0.0 0.022 13.7 0.0 1.5 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 KLO19068.1 - 0.013 15.2 0.2 0.035 13.8 0.0 1.8 2 0 0 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.9 KLO19068.1 - 0.021 13.8 0.0 0.22 10.5 0.0 2.3 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Symplekin_C PF12295.3 KLO19069.1 - 2.5e-58 197.0 0.9 9.5e-58 195.1 0.4 2.2 2 0 0 2 2 2 1 Symplekin tight junction protein C terminal DUF3453 PF11935.3 KLO19069.1 - 7.4e-53 179.4 0.0 1.4e-52 178.4 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3453) HEAT_2 PF13646.1 KLO19069.1 - 0.0017 18.6 0.1 2 8.7 0.0 4.3 3 1 1 4 4 4 1 HEAT repeats HEAT PF02985.17 KLO19069.1 - 0.011 15.7 0.2 0.32 11.1 0.0 3.5 3 0 0 3 3 3 0 HEAT repeat V-ATPase_G PF03179.10 KLO19070.1 - 1.2e-31 109.1 16.1 1.4e-31 108.8 11.2 1.0 1 0 0 1 1 1 1 Vacuolar (H+)-ATPase G subunit RdRP_3 PF00998.18 KLO19070.1 - 0.028 12.9 4.3 0.033 12.6 3.0 1.1 1 0 0 1 1 1 0 Viral RNA dependent RNA polymerase KfrA_N PF11740.3 KLO19070.1 - 0.1 13.0 6.0 0.11 13.0 3.6 1.4 1 1 0 1 1 1 0 Plasmid replication region DNA-binding N-term Striatin PF08232.7 KLO19070.1 - 0.28 11.4 9.4 0.34 11.2 6.5 1.2 1 0 0 1 1 1 0 Striatin family ATP-synt_B PF00430.13 KLO19070.1 - 0.4 10.4 16.8 0.21 11.3 8.0 2.0 1 1 1 2 2 2 0 ATP synthase B/B' CF(0) ATP-synt_F6 PF05511.6 KLO19070.1 - 0.81 9.6 7.8 1 9.2 2.6 2.3 1 1 1 2 2 2 0 Mitochondrial ATP synthase coupling factor 6 Orthopox_B11R PF07033.6 KLO19070.1 - 0.82 9.1 3.5 0.66 9.4 0.8 2.0 1 1 1 2 2 2 0 Orthopoxvirus B11R protein GBP_C PF02841.9 KLO19070.1 - 1 8.4 15.3 1.3 8.1 10.6 1.0 1 0 0 1 1 1 0 Guanylate-binding protein, C-terminal domain DUF16 PF01519.11 KLO19070.1 - 1.1 9.4 14.6 0.24 11.6 7.2 1.7 1 1 1 2 2 2 0 Protein of unknown function DUF16 DUF4407 PF14362.1 KLO19070.1 - 2 7.3 8.4 2.1 7.2 5.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF883 PF05957.8 KLO19070.1 - 2.6 8.4 6.2 3.3 8.1 3.6 1.7 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) PDCD2_C PF04194.8 KLO19070.1 - 4.9 6.7 11.7 3.2 7.3 3.7 2.0 1 1 1 2 2 2 0 Programmed cell death protein 2, C-terminal putative domain Voltage_CLC PF00654.15 KLO19071.1 - 4.8e-87 292.2 26.8 4.7e-86 288.9 17.2 2.1 2 0 0 2 2 2 2 Voltage gated chloride channel CBS PF00571.23 KLO19071.1 - 3.8e-13 48.9 0.0 2.1e-05 24.1 0.0 2.8 2 0 0 2 2 2 2 CBS domain MMS19_N PF14500.1 KLO19073.1 - 1.9e-88 296.1 0.2 2.4e-87 292.5 0.0 2.9 4 0 0 4 4 4 1 Dos2-interacting transcription regulator of RNA-Pol-II MMS19_C PF12460.3 KLO19073.1 - 1.1e-71 241.7 7.7 4.6e-71 239.7 0.1 3.8 4 1 0 4 4 4 1 RNAPII transcription regulator C-terminal HEAT_EZ PF13513.1 KLO19073.1 - 5.5e-06 26.7 4.4 0.048 14.1 0.1 6.0 6 1 1 7 7 7 1 HEAT-like repeat HEAT_2 PF13646.1 KLO19073.1 - 9.4e-06 25.8 4.2 0.11 12.8 0.1 5.3 3 1 1 4 4 4 2 HEAT repeats IFRD PF05004.8 KLO19073.1 - 0.024 13.7 0.3 0.13 11.3 0.1 2.3 3 0 0 3 3 3 0 Interferon-related developmental regulator (IFRD) Methyltransf_28 PF02636.12 KLO19074.1 - 9.4e-35 120.2 0.0 1.4e-34 119.6 0.0 1.2 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase RrnaAD PF00398.15 KLO19074.1 - 0.00011 21.3 0.0 0.00017 20.7 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_12 PF08242.7 KLO19074.1 - 0.0037 17.7 0.0 0.0096 16.3 0.0 1.7 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 KLO19074.1 - 0.0069 15.9 0.0 0.011 15.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KLO19074.1 - 0.017 14.4 0.0 0.036 13.4 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_32 PF13679.1 KLO19074.1 - 0.14 11.8 0.0 0.21 11.2 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain Kei1 PF08552.6 KLO19075.1 - 3.2e-38 131.2 1.1 6.1e-38 130.3 0.8 1.4 1 0 0 1 1 1 1 Inositolphosphorylceramide synthase subunit Kei1 DUF4199 PF13858.1 KLO19075.1 - 0.028 14.3 4.4 0.058 13.3 3.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF4199) p450 PF00067.17 KLO19076.1 - 1e-61 208.9 0.0 1.1e-61 208.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF3083 PF11281.3 KLO19076.1 - 0.025 13.6 0.1 0.038 13.1 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3083) DUF1685 PF07939.6 KLO19076.1 - 0.1 12.2 0.1 1.2 8.8 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1685) Methyltransf_2 PF00891.13 KLO19077.1 - 1.8e-25 89.5 0.0 5.3e-25 88.0 0.0 1.8 1 1 0 1 1 1 1 O-methyltransferase Methyltransf_18 PF12847.2 KLO19077.1 - 3.8e-05 24.2 0.0 9.9e-05 22.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KLO19077.1 - 0.00022 21.6 0.0 0.00044 20.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Dimerisation PF08100.6 KLO19077.1 - 0.00029 20.5 0.0 0.00073 19.3 0.0 1.7 1 0 0 1 1 1 1 Dimerisation domain Methyltransf_23 PF13489.1 KLO19077.1 - 0.00049 19.8 0.0 0.0009 18.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KLO19077.1 - 0.012 15.2 0.0 0.022 14.3 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain MTS PF05175.9 KLO19077.1 - 0.012 14.9 0.0 0.025 13.9 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase small domain MarR_2 PF12802.2 KLO19077.1 - 0.065 12.9 0.0 0.15 11.7 0.0 1.6 1 0 0 1 1 1 0 MarR family RrnaAD PF00398.15 KLO19077.1 - 0.089 11.7 0.0 0.14 11.1 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase RPA_C PF08784.6 KLO19077.1 - 0.16 12.4 0.0 0.37 11.2 0.0 1.5 1 0 0 1 1 1 0 Replication protein A C terminal adh_short PF00106.20 KLO19078.1 - 8.7e-29 100.5 0.8 1.1e-28 100.2 0.6 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KLO19078.1 - 1e-21 77.8 0.1 1.2e-21 77.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KLO19078.1 - 6.6e-10 38.9 0.4 1.5e-09 37.7 0.2 1.6 1 1 0 1 1 1 1 KR domain NmrA PF05368.8 KLO19080.1 - 3.9e-32 111.3 0.0 5.1e-32 110.9 0.0 1.0 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 KLO19080.1 - 4.4e-14 52.8 0.0 6.6e-14 52.3 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 KLO19080.1 - 1.5e-06 27.1 0.0 2.2e-06 26.5 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family TrkA_N PF02254.13 KLO19080.1 - 0.00019 21.4 0.0 0.00032 20.6 0.0 1.4 1 0 0 1 1 1 1 TrkA-N domain Saccharop_dh PF03435.13 KLO19080.1 - 0.0005 19.1 0.0 0.00096 18.2 0.0 1.5 2 0 0 2 2 2 1 Saccharopine dehydrogenase Shikimate_DH PF01488.15 KLO19080.1 - 0.0022 18.0 0.0 0.0038 17.3 0.0 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase GFO_IDH_MocA PF01408.17 KLO19080.1 - 0.0047 17.4 0.0 0.0077 16.7 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold Epimerase PF01370.16 KLO19080.1 - 0.0058 16.0 0.0 0.018 14.4 0.0 1.8 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family NAD_binding_3 PF03447.11 KLO19080.1 - 0.0087 16.4 0.1 0.72 10.2 0.1 2.3 1 1 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain DUF2095 PF09868.4 KLO19080.1 - 0.033 13.9 0.1 0.055 13.2 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2095) DapB_N PF01113.15 KLO19080.1 - 0.13 12.1 0.0 0.29 11.0 0.0 1.6 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Ldh_1_N PF00056.18 KLO19080.1 - 0.14 11.9 0.1 0.21 11.4 0.1 1.2 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain Pyr_redox_3 PF13738.1 KLO19083.1 - 6.7e-22 78.5 0.0 1.4e-20 74.2 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 KLO19083.1 - 1.8e-21 75.9 0.0 1.5e-19 69.6 0.0 2.8 3 0 0 3 3 3 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.1 KLO19083.1 - 3.4e-13 49.2 0.3 9.1e-12 44.5 0.0 2.6 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 KLO19083.1 - 4e-13 49.6 0.0 5.5e-09 36.1 0.1 2.6 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 KLO19083.1 - 5.7e-11 42.4 0.0 0.024 14.4 0.0 3.3 3 0 0 3 3 3 3 FAD-NAD(P)-binding NAD_binding_8 PF13450.1 KLO19083.1 - 1e-07 31.8 0.2 3e-06 27.1 0.0 3.0 3 0 0 3 3 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 KLO19083.1 - 2.5e-07 29.9 0.3 0.027 13.3 0.2 3.2 3 0 0 3 3 3 2 FAD dependent oxidoreductase HI0933_like PF03486.9 KLO19083.1 - 1e-06 27.4 0.7 0.0048 15.4 0.3 3.0 3 0 0 3 3 3 2 HI0933-like protein Pyr_redox PF00070.22 KLO19083.1 - 1.2e-05 25.6 0.6 0.21 12.0 0.1 3.3 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 KLO19083.1 - 0.00015 20.7 0.3 0.023 13.5 0.4 2.3 2 0 0 2 2 2 1 FAD binding domain Mqo PF06039.10 KLO19083.1 - 0.00019 19.7 0.0 0.0003 19.0 0.0 1.3 1 0 0 1 1 1 1 Malate:quinone oxidoreductase (Mqo) Thi4 PF01946.12 KLO19083.1 - 0.00034 19.7 0.3 0.0012 17.9 0.0 1.9 2 0 0 2 2 2 1 Thi4 family FAD_binding_3 PF01494.14 KLO19083.1 - 0.00055 19.0 0.4 0.00098 18.2 0.3 1.4 1 0 0 1 1 1 1 FAD binding domain NAD_binding_7 PF13241.1 KLO19083.1 - 0.00098 19.3 0.0 1.5 9.1 0.0 2.6 2 0 0 2 2 2 2 Putative NAD(P)-binding NAD_binding_10 PF13460.1 KLO19083.1 - 0.0026 17.8 1.7 0.33 10.9 0.3 2.3 2 0 0 2 2 2 1 NADH(P)-binding Amino_oxidase PF01593.19 KLO19083.1 - 0.008 15.2 0.0 0.18 10.8 0.0 2.6 3 0 0 3 3 3 1 Flavin containing amine oxidoreductase Shikimate_DH PF01488.15 KLO19083.1 - 0.014 15.5 0.5 0.82 9.7 0.1 2.3 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase 2-Hacid_dh_C PF02826.14 KLO19083.1 - 0.049 12.7 0.0 0.69 9.0 0.0 2.2 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 3HCDH_N PF02737.13 KLO19083.1 - 0.085 12.5 1.2 0.58 9.7 0.1 2.1 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain GIDA PF01134.17 KLO19083.1 - 0.12 11.1 4.1 3.3 6.4 0.4 2.9 4 0 0 4 4 4 0 Glucose inhibited division protein A ApbA PF02558.11 KLO19083.1 - 0.28 10.6 1.9 0.24 10.8 0.3 1.6 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA F420_oxidored PF03807.12 KLO19083.1 - 0.43 11.0 1.7 4.9 7.6 0.2 2.4 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent PQ-loop PF04193.9 KLO19084.1 - 7e-30 102.3 7.9 5e-18 64.3 0.1 2.8 3 0 0 3 3 3 2 PQ loop repeat DUF3643 PF12356.3 KLO19084.1 - 0.14 11.5 0.6 0.2 10.9 0.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3643) MtN3_slv PF03083.11 KLO19084.1 - 0.14 11.9 5.6 0.14 12.0 0.5 2.5 2 0 0 2 2 2 0 Sugar efflux transporter for intercellular exchange BatA PF07584.6 KLO19084.1 - 0.56 10.4 3.4 24 5.1 0.0 3.0 3 0 0 3 3 3 0 Aerotolerance regulator N-terminal DUF2878 PF11086.3 KLO19084.1 - 0.6 10.0 11.4 0.067 13.1 3.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2878) TPT PF03151.11 KLO19085.1 - 9.6e-33 112.9 8.7 9.6e-33 112.9 6.1 2.1 2 0 0 2 2 2 1 Triose-phosphate Transporter family UAA PF08449.6 KLO19085.1 - 1.5e-14 53.6 18.6 1.9e-14 53.2 12.9 1.1 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.15 KLO19085.1 - 3.6e-11 43.1 27.5 1.1e-07 31.8 4.3 3.3 2 1 1 3 3 3 2 EamA-like transporter family Nuc_sug_transp PF04142.10 KLO19085.1 - 0.0034 16.5 0.4 0.19 10.8 0.0 2.4 2 1 0 2 2 2 1 Nucleotide-sugar transporter Rsm1 PF08600.5 KLO19085.1 - 0.04 13.7 0.0 0.081 12.7 0.0 1.4 1 0 0 1 1 1 0 Rsm1-like ABC_tran PF00005.22 KLO19086.1 - 3.5e-21 75.9 0.0 7.3e-21 74.9 0.0 1.5 1 1 0 1 1 1 1 ABC transporter SMC_N PF02463.14 KLO19086.1 - 5.1e-06 25.8 2.3 0.02 14.0 0.0 2.2 1 1 1 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 KLO19086.1 - 2.2e-05 24.5 0.0 0.0027 17.7 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.1 KLO19086.1 - 0.00055 19.4 0.1 0.0011 18.4 0.1 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain DUF258 PF03193.11 KLO19086.1 - 0.0011 18.1 0.0 0.0027 16.9 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function, DUF258 FtsK_SpoIIIE PF01580.13 KLO19086.1 - 0.0073 15.8 0.0 0.013 15.0 0.0 1.3 1 0 0 1 1 1 1 FtsK/SpoIIIE family AAA_23 PF13476.1 KLO19086.1 - 0.013 15.7 0.1 0.013 15.7 0.1 1.9 2 1 0 2 2 2 0 AAA domain AAA_17 PF13207.1 KLO19086.1 - 0.017 15.9 1.8 0.032 15.0 0.3 2.5 2 1 0 2 2 2 0 AAA domain AAA_22 PF13401.1 KLO19086.1 - 0.025 14.7 0.0 0.076 13.1 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_13 PF13166.1 KLO19086.1 - 0.031 12.7 0.2 0.98 7.7 0.1 2.1 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.1 KLO19086.1 - 0.04 13.8 0.0 0.071 13.0 0.0 1.7 1 1 0 1 1 1 0 AAA ATPase domain AAA_10 PF12846.2 KLO19086.1 - 0.053 12.9 0.3 0.16 11.3 0.0 1.8 2 0 0 2 2 2 0 AAA-like domain AAA_30 PF13604.1 KLO19086.1 - 0.064 12.8 0.0 0.14 11.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain SbcCD_C PF13558.1 KLO19086.1 - 0.1 12.5 0.4 0.29 11.0 0.3 1.8 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_18 PF13238.1 KLO19086.1 - 0.11 12.8 0.2 0.83 9.9 0.0 2.5 3 0 0 3 3 3 0 AAA domain ABC_tran PF00005.22 KLO19087.1 - 1.3e-20 74.0 0.0 2.5e-20 73.1 0.0 1.5 1 1 0 1 1 1 1 ABC transporter SMC_N PF02463.14 KLO19087.1 - 1.2e-06 27.9 0.2 0.0041 16.3 0.0 2.3 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 KLO19087.1 - 0.00011 22.2 0.0 0.016 15.2 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.1 KLO19087.1 - 0.001 18.5 0.0 0.0021 17.5 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain DUF258 PF03193.11 KLO19087.1 - 0.0073 15.5 0.0 0.018 14.2 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_22 PF13401.1 KLO19087.1 - 0.029 14.5 0.1 0.2 11.8 0.1 2.1 1 1 0 1 1 1 0 AAA domain AAA_30 PF13604.1 KLO19087.1 - 0.057 12.9 0.1 0.18 11.3 0.0 1.8 2 0 0 2 2 2 0 AAA domain Hydrolase_4 PF12146.3 KLO19087.1 - 0.065 13.1 0.0 0.15 11.9 0.0 1.6 1 0 0 1 1 1 0 Putative lysophospholipase SRP54 PF00448.17 KLO19087.1 - 0.11 11.8 0.0 0.22 10.9 0.0 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_16 PF13191.1 KLO19087.1 - 0.12 12.3 0.0 0.24 11.3 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain AAA_33 PF13671.1 KLO19087.1 - 0.14 12.0 0.0 0.29 10.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain SbcCD_C PF13558.1 KLO19087.1 - 0.2 11.6 1.4 0.58 10.1 0.4 2.2 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit SCA7 PF08313.7 KLO19088.1 - 2.8e-28 97.3 0.3 2.8e-28 97.3 0.2 2.3 1 1 1 2 2 2 1 SCA7, zinc-binding domain TraV PF09676.5 KLO19088.1 - 7.1 7.3 7.7 6.5 7.4 1.2 2.4 2 0 0 2 2 2 0 Type IV conjugative transfer system lipoprotein (TraV) IF4E PF01652.13 KLO19089.1 - 5.7e-47 159.3 0.1 7.4e-47 158.9 0.1 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E DUF1917 PF08939.5 KLO19089.1 - 0.0021 17.8 0.1 0.0038 17.0 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1917) MSP1a PF11670.3 KLO19089.1 - 0.72 9.6 9.9 1.5 8.6 6.9 1.5 1 0 0 1 1 1 0 Major surface protein 1a (MSP1a) Tmemb_14 PF03647.8 KLO19090.1 - 5.4e-18 65.1 7.2 6.3e-18 64.9 5.0 1.1 1 0 0 1 1 1 1 Transmembrane proteins 14C Bundlin PF05307.6 KLO19090.1 - 0.084 12.7 0.3 4 7.3 0.1 2.1 1 1 1 2 2 2 0 Bundlin UbiA PF01040.13 KLO19090.1 - 3.8 6.6 8.0 5.9 6.0 5.5 1.3 1 1 0 1 1 1 0 UbiA prenyltransferase family SIR2 PF02146.12 KLO19092.1 - 2.2e-59 200.1 0.0 3.4e-59 199.5 0.0 1.3 1 0 0 1 1 1 1 Sir2 family DUF592 PF04574.8 KLO19092.1 - 5e-07 29.4 1.2 5.3e-05 22.8 0.3 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF592) TPP_enzyme_M PF00205.17 KLO19092.1 - 0.049 13.3 0.3 12 5.6 0.1 2.4 2 0 0 2 2 2 0 Thiamine pyrophosphate enzyme, central domain AbiH PF14253.1 KLO19092.1 - 1.6 8.2 5.4 0.2 11.2 0.1 1.9 2 0 0 2 2 2 0 Bacteriophage abortive infection AbiH Acetyltransf_10 PF13673.1 KLO19093.1 - 1.6e-08 34.6 0.0 2.9e-08 33.8 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 KLO19093.1 - 5.7e-06 26.2 0.0 9.2e-06 25.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 KLO19093.1 - 6.9e-06 26.1 0.0 1.2e-05 25.3 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 KLO19093.1 - 0.0046 16.6 0.0 0.0068 16.1 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein RVT_1 PF00078.22 KLO19096.1 - 4.3e-07 29.4 0.0 8.4e-07 28.5 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) TP_methylase PF00590.15 KLO19097.1 - 3.6e-40 137.9 0.9 5.5e-40 137.3 0.6 1.3 1 0 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases NAD_binding_7 PF13241.1 KLO19097.1 - 1.8e-12 47.4 0.1 4.9e-12 45.9 0.0 1.8 1 1 0 1 1 1 1 Putative NAD(P)-binding Sirohm_synth_C PF14823.1 KLO19097.1 - 5.2e-07 28.8 0.1 0.00022 20.4 0.0 2.5 2 0 0 2 2 2 2 Sirohaem biosynthesis protein C-terminal Sirohm_synth_M PF14824.1 KLO19097.1 - 3e-05 22.8 0.0 6.7e-05 21.7 0.0 1.5 1 0 0 1 1 1 1 Sirohaem biosynthesis protein central Abhydrolase_5 PF12695.2 KLO19099.1 - 3.4e-15 56.0 0.0 1.3e-13 50.9 0.0 2.9 2 1 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KLO19099.1 - 8.5e-14 51.9 0.5 7.6e-13 48.8 0.0 2.7 3 1 0 3 3 3 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KLO19099.1 - 6.7e-09 35.6 0.0 1.6e-08 34.4 0.0 1.7 2 0 0 2 2 2 1 alpha/beta hydrolase fold BAAT_C PF08840.6 KLO19099.1 - 0.0026 17.5 0.0 0.01 15.5 0.0 1.8 2 0 0 2 2 2 1 BAAT / Acyl-CoA thioester hydrolase C terminal DLH PF01738.13 KLO19099.1 - 0.23 10.6 0.0 0.48 9.6 0.0 1.4 1 0 0 1 1 1 0 Dienelactone hydrolase family ABC_tran PF00005.22 KLO19100.1 - 5.3e-22 78.5 0.0 9.1e-22 77.8 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 KLO19100.1 - 2.6e-09 37.4 0.0 3.9e-08 33.6 0.0 2.3 1 1 0 1 1 1 1 AAA domain SMC_N PF02463.14 KLO19100.1 - 3.1e-05 23.3 0.1 0.081 12.1 0.1 2.3 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 KLO19100.1 - 0.011 16.1 0.4 0.031 14.5 0.0 1.9 2 1 0 2 2 2 0 AAA domain AAA_29 PF13555.1 KLO19100.1 - 0.014 14.8 0.0 0.029 13.8 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_22 PF13401.1 KLO19100.1 - 0.023 14.8 0.0 0.059 13.5 0.0 1.8 1 1 0 1 1 1 0 AAA domain DUF258 PF03193.11 KLO19100.1 - 0.044 12.9 0.0 0.078 12.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_16 PF13191.1 KLO19100.1 - 0.049 13.6 0.0 0.088 12.7 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain AAA_30 PF13604.1 KLO19100.1 - 0.1 12.1 0.0 0.24 10.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain SbcCD_C PF13558.1 KLO19100.1 - 0.12 12.2 0.2 0.34 10.8 0.2 1.8 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit ABC_tran PF00005.22 KLO19102.1 - 2e-21 76.7 0.0 3.9e-21 75.7 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 KLO19102.1 - 3.7e-09 36.9 0.1 1.6e-07 31.5 0.0 2.8 2 1 0 2 2 2 1 AAA domain SMC_N PF02463.14 KLO19102.1 - 0.00011 21.4 0.1 0.13 11.4 0.1 2.5 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.1 KLO19102.1 - 0.0093 15.9 0.0 0.11 12.4 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain AAA_23 PF13476.1 KLO19102.1 - 0.014 15.6 0.2 0.039 14.2 0.1 1.7 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.1 KLO19102.1 - 0.018 14.5 0.0 0.039 13.4 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF258 PF03193.11 KLO19102.1 - 0.036 13.2 0.0 0.074 12.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_22 PF13401.1 KLO19102.1 - 0.095 12.8 0.0 0.28 11.3 0.0 1.8 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.7 KLO19102.1 - 0.17 10.9 0.0 0.31 10.1 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin Ribosomal_L5_C PF00673.16 KLO19103.1 - 3.3e-22 78.0 0.0 4.8e-22 77.4 0.0 1.3 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.14 KLO19103.1 - 8e-21 73.5 0.4 3.7e-20 71.4 0.0 2.1 2 0 0 2 2 2 1 Ribosomal protein L5 DAGAT PF03982.8 KLO19104.1 - 1.4e-97 325.9 0.0 1.6e-97 325.7 0.0 1.0 1 0 0 1 1 1 1 Diacylglycerol acyltransferase DUF1104 PF06518.6 KLO19105.1 - 0.011 15.8 0.0 0.015 15.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1104) FCD PF07729.7 KLO19105.1 - 0.039 14.2 1.4 0.068 13.4 0.9 1.4 1 0 0 1 1 1 0 FCD domain Rxt3 PF08642.5 KLO19106.1 - 0.0046 17.1 0.0 0.025 14.8 0.0 2.3 2 0 0 2 2 2 1 Histone deacetylation protein Rxt3 DUF1640 PF07798.6 KLO19107.1 - 8.8e-62 208.2 11.0 1e-61 208.0 7.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1640) DUF4515 PF14988.1 KLO19107.1 - 0.0045 16.6 7.4 0.0064 16.1 5.2 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4515) Docking PF08990.6 KLO19107.1 - 0.15 11.3 2.7 0.16 11.2 0.4 2.2 2 0 0 2 2 2 0 Erythronolide synthase docking DUF2077 PF09850.4 KLO19107.1 - 0.25 10.7 3.6 1.8 7.9 0.0 2.8 2 1 1 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2077) DDE_Tnp_IS1 PF03400.8 KLO19107.1 - 1.2 9.2 4.2 6 6.9 0.1 2.9 1 1 2 3 3 3 0 IS1 transposase DUF2115 PF09888.4 KLO19107.1 - 2.3 8.2 7.7 1.1 9.4 2.1 2.0 1 1 1 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2115) Ran_BP1 PF00638.13 KLO19108.1 - 1.3e-16 60.7 0.0 2.4e-16 59.8 0.0 1.4 1 0 0 1 1 1 1 RanBP1 domain Trypan_PARP PF05887.6 KLO19108.1 - 0.0055 16.5 6.9 0.0055 16.5 4.8 4.2 4 1 0 4 4 4 1 Procyclic acidic repetitive protein (PARP) ESCRT-II PF05871.7 KLO19109.1 - 3.6e-33 114.4 0.1 4.6e-33 114.0 0.1 1.1 1 0 0 1 1 1 1 ESCRT-II complex subunit ABC_tran PF00005.22 KLO19110.1 - 5.6e-23 81.7 0.0 8.8e-23 81.1 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 KLO19110.1 - 3.2e-11 43.7 0.0 1.3e-10 41.6 0.0 1.9 1 1 0 1 1 1 1 AAA domain SMC_N PF02463.14 KLO19110.1 - 2.7e-06 26.8 0.3 0.064 12.4 0.5 2.2 1 1 1 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 KLO19110.1 - 0.0016 18.8 0.1 0.0035 17.6 0.1 1.6 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.1 KLO19110.1 - 0.0028 17.1 0.1 0.0058 16.1 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain G-alpha PF00503.15 KLO19110.1 - 0.031 12.9 0.0 0.041 12.5 0.0 1.2 1 0 0 1 1 1 0 G-protein alpha subunit DUF258 PF03193.11 KLO19110.1 - 0.032 13.4 0.0 0.052 12.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 SbcCD_C PF13558.1 KLO19110.1 - 0.039 13.8 0.0 0.13 12.1 0.0 1.9 1 0 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_22 PF13401.1 KLO19110.1 - 0.048 13.8 0.0 0.2 11.7 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.1 KLO19110.1 - 0.049 13.6 0.0 0.087 12.8 0.0 1.7 1 1 0 1 1 1 0 AAA ATPase domain AAA_15 PF13175.1 KLO19110.1 - 0.075 12.0 0.0 0.77 8.7 0.0 2.0 2 0 0 2 2 2 0 AAA ATPase domain FtsK_SpoIIIE PF01580.13 KLO19110.1 - 0.099 12.1 0.1 0.19 11.1 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family F-box-like PF12937.2 KLO19111.1 - 8.3e-06 25.4 3.8 1.1e-05 25.0 0.7 2.6 2 1 0 2 2 2 1 F-box-like F-box-like PF12937.2 KLO19112.1 - 1.1e-06 28.2 1.4 1.1e-06 28.2 1.0 2.5 2 1 0 2 2 2 1 F-box-like DWNN PF08783.6 KLO19113.1 - 1.2e-28 98.8 0.5 2.4e-28 97.8 0.4 1.5 1 0 0 1 1 1 1 DWNN domain zf-CCHC_2 PF13696.1 KLO19113.1 - 1.5e-07 30.7 3.2 3.8e-07 29.4 2.2 1.6 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC PF00098.18 KLO19113.1 - 2.5e-05 23.9 2.5 2.5e-05 23.9 1.7 2.2 2 0 0 2 2 2 1 Zinc knuckle zf-CCHC_3 PF13917.1 KLO19113.1 - 0.00025 20.6 0.4 0.00068 19.3 0.3 1.7 1 0 0 1 1 1 1 Zinc knuckle zf-C3HC4_2 PF13923.1 KLO19113.1 - 0.0017 18.3 8.3 0.0017 18.3 5.8 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-CCHC_5 PF14787.1 KLO19113.1 - 0.007 15.8 0.8 0.007 15.8 0.5 1.9 2 0 0 2 2 2 1 GAG-polyprotein viral zinc-finger zf-RING_2 PF13639.1 KLO19113.1 - 0.0075 16.0 6.1 0.0075 16.0 4.2 1.7 2 0 0 2 2 2 1 Ring finger domain CCDC-167 PF15188.1 KLO19113.1 - 0.11 12.4 0.0 0.11 12.4 0.0 2.7 3 0 0 3 3 3 0 Coiled-coil domain-containing protein 167 zf-C3HC4_4 PF15227.1 KLO19113.1 - 0.42 10.5 9.2 0.96 9.3 6.4 1.7 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING DUF4428 PF14471.1 KLO19113.1 - 0.6 9.9 5.0 0.44 10.3 0.5 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4428) zf-C3HC4 PF00097.20 KLO19113.1 - 0.62 9.7 9.0 1.3 8.7 6.3 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KLO19113.1 - 1.1 9.0 10.7 0.079 12.6 3.4 1.9 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) HATPase_c PF02518.21 KLO19114.1 - 7.4e-23 80.3 0.1 1.8e-22 79.1 0.1 1.7 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 KLO19114.1 - 3.9e-16 59.0 0.1 2.2e-08 34.1 0.0 2.5 2 0 0 2 2 2 2 Response regulator receiver domain HisKA PF00512.20 KLO19114.1 - 5.3e-07 29.5 0.0 1.3e-06 28.3 0.0 1.7 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain HATPase_c_3 PF13589.1 KLO19114.1 - 0.015 14.9 0.1 0.034 13.8 0.1 1.5 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase ISN1 PF06437.6 KLO19114.1 - 0.081 11.6 0.1 0.12 11.0 0.1 1.1 1 0 0 1 1 1 0 IMP-specific 5'-nucleotidase Ribosomal_L28e PF01778.12 KLO19115.1 - 1.7e-30 105.8 1.5 1.7e-30 105.8 1.0 1.9 2 0 0 2 2 2 1 Ribosomal L28e protein family Mak16 PF04874.9 KLO19115.1 - 8.7e-19 67.4 19.7 8.7e-19 67.4 13.6 3.1 2 1 1 3 3 3 1 Mak16 protein C-terminal region BUD22 PF09073.5 KLO19115.1 - 0.00032 19.9 15.8 0.00042 19.5 11.0 1.2 1 0 0 1 1 1 1 BUD22 CENP-T PF15511.1 KLO19115.1 - 0.49 9.5 15.6 0.65 9.1 10.8 1.1 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T Nop14 PF04147.7 KLO19115.1 - 0.87 7.4 21.1 1.3 6.8 14.7 1.3 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.9 KLO19115.1 - 3 5.7 12.8 4.7 5.1 8.9 1.3 1 0 0 1 1 1 0 CDC45-like protein NRDD PF13597.1 KLO19116.1 - 0.13 10.3 0.0 0.17 9.8 0.0 1.1 1 0 0 1 1 1 0 Anaerobic ribonucleoside-triphosphate reductase F-box-like PF12937.2 KLO19117.1 - 9.9e-09 34.7 1.6 2.2e-08 33.6 0.1 2.4 2 0 0 2 2 2 1 F-box-like ArgJ PF01960.13 KLO19118.1 - 2e-136 454.4 0.4 2.3e-136 454.2 0.3 1.0 1 0 0 1 1 1 1 ArgJ family DUF2383 PF09537.5 KLO19118.1 - 0.093 12.9 0.1 0.18 12.0 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF2383) PNK3P PF08645.6 KLO19121.1 - 1.3e-44 151.4 0.1 2e-44 150.8 0.1 1.3 1 0 0 1 1 1 1 Polynucleotide kinase 3 phosphatase AAA_33 PF13671.1 KLO19121.1 - 2.5e-13 50.1 0.0 1.3e-12 47.7 0.0 2.1 1 1 0 1 1 1 1 AAA domain LNS2 PF08235.8 KLO19121.1 - 9.6e-05 21.9 0.0 0.00017 21.1 0.0 1.5 1 0 0 1 1 1 1 LNS2 (Lipin/Ned1/Smp2) HAD_2 PF13419.1 KLO19121.1 - 0.05 13.8 0.5 12 6.0 0.0 2.9 2 1 1 3 3 3 0 Haloacid dehalogenase-like hydrolase SRPRB PF09439.5 KLO19121.1 - 0.074 12.2 0.0 0.12 11.6 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit Ribosomal_L35Ae PF01247.13 KLO19123.1 - 3.1e-42 142.2 0.6 3.5e-42 142.0 0.4 1.0 1 0 0 1 1 1 1 Ribosomal protein L35Ae RimM PF01782.13 KLO19123.1 - 0.00084 19.2 0.0 1.3 9.0 0.0 2.2 2 0 0 2 2 2 2 RimM N-terminal domain Abhydrolase_3 PF07859.8 KLO19124.1 - 1.5e-17 63.8 0.0 3.4e-17 62.7 0.0 1.5 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KLO19124.1 - 7.2e-11 42.0 0.0 1.1e-10 41.3 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 KLO19124.1 - 3.5e-05 23.1 0.0 0.079 12.1 0.0 2.4 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_6 PF12697.2 KLO19124.1 - 0.0014 18.5 0.0 0.0021 17.9 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Chlorophyllase2 PF12740.2 KLO19124.1 - 0.0017 17.2 0.0 0.0027 16.6 0.0 1.3 1 0 0 1 1 1 1 Chlorophyllase enzyme zf-RING_2 PF13639.1 KLO19125.1 - 1.8e-10 40.4 2.9 6.5e-09 35.4 0.4 2.4 2 0 0 2 2 2 1 Ring finger domain zf-rbx1 PF12678.2 KLO19125.1 - 8.5e-08 32.1 0.9 5.8e-07 29.5 0.2 2.3 2 0 0 2 2 2 1 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 KLO19125.1 - 1e-05 25.4 0.9 1e-05 25.4 0.6 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KLO19125.1 - 2e-05 24.1 2.1 3e-05 23.5 0.4 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KLO19125.1 - 4e-05 23.2 0.4 0.0001 21.9 0.3 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.20 KLO19125.1 - 4.1e-05 23.1 3.9 5.5e-05 22.7 0.4 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 KLO19125.1 - 0.0021 17.8 0.2 0.0052 16.5 0.2 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger PQ-loop PF04193.9 KLO19125.1 - 0.0066 15.9 0.8 0.019 14.5 0.5 1.7 1 0 0 1 1 1 1 PQ loop repeat zf-RING_UBOX PF13445.1 KLO19125.1 - 0.071 12.8 0.3 0.19 11.4 0.2 1.7 1 0 0 1 1 1 0 RING-type zinc-finger zf-RING_4 PF14570.1 KLO19125.1 - 0.14 11.8 1.0 0.3 10.6 0.7 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Rtf2 PF04641.7 KLO19125.1 - 0.36 10.0 0.1 0.87 8.7 0.0 1.6 2 0 0 2 2 2 0 Rtf2 RING-finger FANCL_C PF11793.3 KLO19125.1 - 1 9.3 4.0 1.4 8.9 1.3 2.3 2 1 0 2 2 2 0 FANCL C-terminal domain RINGv PF12906.2 KLO19125.1 - 5.9 7.0 6.5 0.78 9.8 1.5 1.8 2 0 0 2 2 2 0 RING-variant domain Nnf1 PF03980.9 KLO19126.1 - 9.7e-10 38.4 0.6 2e-09 37.4 0.4 1.5 1 0 0 1 1 1 1 Nnf1 CASP_C PF08172.7 KLO19126.1 - 0.00032 19.7 1.4 0.00045 19.3 1.0 1.3 1 0 0 1 1 1 1 CASP C terminal CENP-F_leu_zip PF10473.4 KLO19126.1 - 0.0045 16.8 2.1 0.0057 16.5 1.5 1.3 1 0 0 1 1 1 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Not3 PF04065.10 KLO19126.1 - 0.0059 15.9 0.7 0.0077 15.5 0.5 1.3 1 0 0 1 1 1 1 Not1 N-terminal domain, CCR4-Not complex component IncA PF04156.9 KLO19126.1 - 0.0064 16.1 1.4 0.0089 15.6 0.9 1.3 1 0 0 1 1 1 1 IncA protein Spc24 PF08286.6 KLO19126.1 - 0.007 16.0 0.7 0.012 15.3 0.5 1.3 1 0 0 1 1 1 1 Spc24 subunit of Ndc80 APG6 PF04111.7 KLO19126.1 - 0.011 14.7 1.9 0.014 14.4 1.3 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 Herpes_BLRF2 PF05812.7 KLO19126.1 - 0.024 14.4 3.0 0.029 14.1 1.3 1.7 2 0 0 2 2 2 0 Herpesvirus BLRF2 protein Mnd1 PF03962.10 KLO19126.1 - 0.024 14.2 2.3 0.033 13.8 1.6 1.2 1 0 0 1 1 1 0 Mnd1 family Jnk-SapK_ap_N PF09744.4 KLO19126.1 - 0.032 14.2 1.4 0.069 13.1 1.0 1.5 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 Striatin PF08232.7 KLO19126.1 - 0.041 14.1 3.7 0.084 13.1 2.6 1.5 1 0 0 1 1 1 0 Striatin family AKNA PF12443.3 KLO19126.1 - 0.089 12.8 0.4 0.29 11.1 0.1 1.9 2 1 0 2 2 2 0 AT-hook-containing transcription factor BMFP PF04380.8 KLO19126.1 - 0.13 12.4 4.7 1.7 8.8 0.0 2.8 2 1 1 3 3 3 0 Membrane fusogenic activity PhoU PF01895.14 KLO19126.1 - 1.4 9.4 5.8 1.3 9.5 2.7 1.8 2 0 0 2 2 2 0 PhoU domain Herpes_UL6 PF01763.11 KLO19126.1 - 3.5 5.7 7.1 0.41 8.7 1.3 1.8 1 1 1 2 2 2 0 Herpesvirus UL6 like Atg14 PF10186.4 KLO19126.1 - 3.9 6.3 7.2 5.5 5.8 5.0 1.3 1 1 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DivIC PF04977.10 KLO19126.1 - 6.2 6.3 8.3 0.79 9.2 2.7 1.8 2 0 0 2 2 2 0 Septum formation initiator zf-C2H2_jaz PF12171.3 KLO19127.1 - 2e-10 40.5 1.9 3.6e-10 39.6 1.3 1.4 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 KLO19127.1 - 0.00015 21.8 0.9 0.00031 20.8 0.6 1.6 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.2 KLO19127.1 - 0.018 15.1 0.2 0.018 15.1 0.1 1.4 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) IQ PF00612.22 KLO19127.1 - 0.17 11.6 0.6 0.17 11.6 0.4 2.1 2 0 0 2 2 2 0 IQ calmodulin-binding motif Pirin PF02678.11 KLO19128.1 - 1.4e-26 92.4 1.9 2.2e-26 91.7 1.3 1.3 1 0 0 1 1 1 1 Pirin Cupin_2 PF07883.6 KLO19128.1 - 8.1e-06 25.2 1.0 0.00079 18.8 0.7 2.3 2 0 0 2 2 2 2 Cupin domain UQ_con PF00179.21 KLO19129.1 - 3.7e-17 62.0 0.0 4.2e-17 61.8 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 KLO19129.1 - 0.066 13.1 0.0 0.069 13.0 0.0 1.2 1 0 0 1 1 1 0 RWD domain VHS PF00790.14 KLO19130.1 - 1.6e-26 92.6 1.3 2.5e-26 91.9 0.9 1.3 1 0 0 1 1 1 1 VHS domain SH3_9 PF14604.1 KLO19130.1 - 1.9e-17 62.5 0.2 3.6e-17 61.6 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 KLO19130.1 - 9e-17 60.2 0.1 1.7e-16 59.3 0.1 1.5 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 KLO19130.1 - 2.5e-13 49.2 0.1 4.7e-13 48.4 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain GAT PF03127.9 KLO19130.1 - 4.9e-05 23.2 1.4 0.00017 21.4 0.6 2.2 2 0 0 2 2 2 1 GAT domain Anoctamin PF04547.7 KLO19131.1 - 2.3e-97 326.4 0.4 3e-97 326.1 0.3 1.1 1 0 0 1 1 1 1 Calcium-activated chloride channel WD40 PF00400.27 KLO19136.1 - 5.2e-84 273.4 25.4 3.3e-11 42.5 0.3 8.3 8 0 0 8 8 8 8 WD domain, G-beta repeat NLE PF08154.7 KLO19136.1 - 1.3e-09 37.9 0.1 2.4e-09 37.0 0.0 1.4 1 0 0 1 1 1 1 NLE (NUC135) domain Nup160 PF11715.3 KLO19136.1 - 1.8e-08 33.0 7.5 0.0037 15.4 0.0 4.3 3 1 2 5 5 5 3 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 KLO19136.1 - 0.00028 19.7 0.9 1.1 7.9 0.0 3.6 3 2 1 4 4 4 2 Nup133 N terminal like IKI3 PF04762.7 KLO19136.1 - 0.22 9.2 0.0 0.33 8.7 0.0 1.2 1 0 0 1 1 1 0 IKI3 family Mit_ribos_Mrp51 PF11709.3 KLO19139.1 - 1.6e-13 50.5 5.2 7.2e-13 48.4 3.6 2.0 1 1 0 1 1 1 1 Mitochondrial ribosomal protein subunit Ferritin PF00210.19 KLO19139.1 - 0.036 13.8 0.0 0.07 12.8 0.0 1.4 1 0 0 1 1 1 0 Ferritin-like domain Nuc_sug_transp PF04142.10 KLO19140.1 - 5.9e-76 254.7 6.0 9.7e-76 254.0 4.2 1.3 1 0 0 1 1 1 1 Nucleotide-sugar transporter UAA PF08449.6 KLO19140.1 - 2.2e-06 26.8 9.8 4e-06 25.9 6.8 1.3 1 0 0 1 1 1 1 UAA transporter family EmrE PF13536.1 KLO19140.1 - 2.2e-05 24.6 4.6 2.2e-05 24.6 3.2 2.9 3 0 0 3 3 3 1 Multidrug resistance efflux transporter TPT PF03151.11 KLO19140.1 - 4.6e-05 23.1 3.3 4.6e-05 23.1 2.3 3.1 2 2 0 2 2 2 1 Triose-phosphate Transporter family EamA PF00892.15 KLO19140.1 - 0.0014 18.6 7.6 0.0014 18.6 5.3 3.1 2 2 0 2 2 2 1 EamA-like transporter family DUF454 PF04304.8 KLO19140.1 - 3.9 7.5 7.8 6 6.9 1.3 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF454) DUF2404 PF10296.4 KLO19141.1 - 0.00085 19.4 0.0 0.0052 16.8 0.0 2.1 2 0 0 2 2 2 1 Putative integral membrane protein conserved region (DUF2404) Radical_SAM PF04055.16 KLO19142.1 - 2e-16 60.5 0.1 7.2e-16 58.7 0.0 1.8 2 0 0 2 2 2 1 Radical SAM superfamily Acetyltransf_1 PF00583.19 KLO19142.1 - 4.6e-11 42.5 0.1 1.3e-10 41.1 0.0 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 KLO19142.1 - 0.048 13.7 0.0 0.2 11.8 0.0 2.0 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain DUF515 PF04415.7 KLO19143.1 - 1.4 7.0 9.9 2.7 6.1 6.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF515) Rep_fac-A_C PF08646.5 KLO19144.1 - 2.6e-49 166.6 4.5 3.8e-47 159.6 1.9 2.8 3 0 0 3 3 3 2 Replication factor-A C terminal domain Rep-A_N PF04057.7 KLO19144.1 - 1.2e-22 79.6 0.7 2.8e-22 78.4 0.5 1.7 1 0 0 1 1 1 1 Replication factor-A protein 1, N-terminal domain tRNA_anti-codon PF01336.20 KLO19144.1 - 2e-14 53.2 0.0 5.8e-12 45.2 0.0 2.6 2 0 0 2 2 2 2 OB-fold nucleic acid binding domain DUF223 PF02721.9 KLO19144.1 - 1e-05 25.5 0.1 0.00032 20.7 0.0 3.0 3 0 0 3 3 3 1 Domain of unknown function DUF223 DUF4539 PF15072.1 KLO19144.1 - 0.034 13.8 0.0 0.086 12.5 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4539) TraB PF01963.12 KLO19144.1 - 0.062 12.7 0.0 0.1 11.9 0.0 1.3 1 0 0 1 1 1 0 TraB family Peptidase_M16 PF00675.15 KLO19145.1 - 7.6e-37 126.3 0.2 1.6e-35 122.0 0.1 2.6 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.16 KLO19145.1 - 3.7e-24 85.4 0.0 8.2e-12 45.1 0.0 3.0 3 0 0 3 3 3 2 Peptidase M16 inactive domain NIF PF03031.13 KLO19146.1 - 4.7e-20 71.8 0.0 8.6e-20 71.0 0.0 1.4 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase ubiquitin PF00240.18 KLO19146.1 - 5.4e-08 32.1 0.0 1e-07 31.2 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family DUF1681 PF07933.9 KLO19147.1 - 1.9e-52 177.0 0.0 2.3e-52 176.8 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1681) DUF4628 PF15429.1 KLO19147.1 - 0.23 10.8 0.1 0.23 10.8 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4628) Glyco_hydro_6 PF01341.12 KLO19148.1 - 3.5e-109 364.8 2.2 4.5e-109 364.4 1.5 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 6 CBM_1 PF00734.13 KLO19148.1 - 3.1e-14 52.3 9.1 3.1e-14 52.3 6.3 2.1 2 0 0 2 2 2 1 Fungal cellulose binding domain Aminotran_5 PF00266.14 KLO19149.1 - 4.3e-95 318.5 0.0 5.1e-95 318.3 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.16 KLO19149.1 - 1.7e-08 33.9 0.1 2.5e-08 33.4 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.12 KLO19149.1 - 3.6e-05 22.9 0.0 0.00016 20.8 0.0 1.8 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family Cys_Met_Meta_PP PF01053.15 KLO19149.1 - 0.0015 16.8 0.0 0.0024 16.2 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme B12-binding PF02310.14 KLO19149.1 - 0.018 14.9 0.0 3.1 7.7 0.0 2.6 2 0 0 2 2 2 0 B12 binding domain Fungal_trans PF04082.13 KLO19150.1 - 3.7e-08 32.5 0.0 6.8e-08 31.6 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KLO19150.1 - 4e-06 26.6 13.6 1.3e-05 24.9 9.5 1.9 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Matrilin_ccoil PF10393.4 KLO19150.1 - 0.018 14.4 0.2 0.036 13.4 0.2 1.5 1 0 0 1 1 1 0 Trimeric coiled-coil oligomerisation domain of matrilin RRM_1 PF00076.17 KLO19151.1 - 5.7e-28 96.3 0.1 1.3e-17 63.1 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KLO19151.1 - 2.6e-21 75.3 0.1 4.4e-13 49.0 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KLO19151.1 - 9.6e-16 57.3 0.1 1.1e-10 41.1 0.1 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 KLO19151.1 - 2.5e-06 27.1 0.2 0.044 13.5 0.0 2.4 2 0 0 2 2 2 2 Limkain b1 RRM_3 PF08777.6 KLO19151.1 - 0.014 15.2 0.1 2.8 7.8 0.0 2.2 2 0 0 2 2 2 0 RNA binding motif Nup35_RRM_2 PF14605.1 KLO19151.1 - 0.039 13.7 0.0 0.15 11.8 0.0 1.9 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif CAP_GLY PF01302.20 KLO19152.1 - 4.4e-20 71.1 0.2 7.2e-20 70.4 0.1 1.4 1 0 0 1 1 1 1 CAP-Gly domain LRR_4 PF12799.2 KLO19152.1 - 2.3e-16 58.9 6.5 0.0013 18.2 0.1 6.1 5 1 1 6 6 6 6 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KLO19152.1 - 9.2e-08 31.7 10.0 0.032 13.9 0.4 5.5 1 1 6 7 7 7 4 Leucine rich repeat LRR_6 PF13516.1 KLO19152.1 - 9.8e-05 22.0 7.8 13 6.2 0.0 7.0 7 0 0 7 7 7 1 Leucine Rich repeat LRR_1 PF00560.28 KLO19152.1 - 0.00032 20.3 6.7 23 5.5 0.1 6.2 5 1 0 5 5 5 0 Leucine Rich Repeat LRR_7 PF13504.1 KLO19152.1 - 0.0021 17.9 7.5 6.1 7.5 0.1 5.9 7 0 0 7 7 7 1 Leucine rich repeat LRR_9 PF14580.1 KLO19152.1 - 0.02 14.4 0.1 0.42 10.1 0.0 2.4 2 1 1 3 3 3 0 Leucine-rich repeat AP_endonuc_2_N PF07582.7 KLO19152.1 - 0.13 11.8 0.0 1.4 8.5 0.0 2.4 2 0 0 2 2 2 0 AP endonuclease family 2 C terminus ECH_C PF13766.1 KLO19153.1 - 3.1e-29 101.5 0.0 6.3e-29 100.5 0.0 1.5 1 0 0 1 1 1 1 2-enoyl-CoA Hydratase C-terminal region ECH PF00378.15 KLO19153.1 - 7.4e-26 90.7 0.0 2.8e-25 88.8 0.0 1.9 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family FliG_N PF14842.1 KLO19153.1 - 0.0042 17.1 0.1 0.045 13.8 0.0 2.2 2 0 0 2 2 2 1 FliG N-terminal domain DUF2497 PF10691.4 KLO19153.1 - 0.068 13.1 3.4 0.21 11.6 0.1 3.1 2 1 0 3 3 3 0 Protein of unknown function (DUF2497) IDO PF01231.13 KLO19154.1 - 4.4e-106 354.8 0.0 5.2e-106 354.6 0.0 1.0 1 0 0 1 1 1 1 Indoleamine 2,3-dioxygenase CKS PF01111.14 KLO19155.1 - 7.6e-35 118.5 0.1 9.6e-35 118.2 0.1 1.1 1 0 0 1 1 1 1 Cyclin-dependent kinase regulatory subunit Pkinase PF00069.20 KLO19156.1 - 8e-44 149.7 0.0 1e-43 149.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KLO19156.1 - 9.8e-27 93.6 0.0 1.3e-26 93.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KLO19156.1 - 0.0015 17.5 0.0 0.0024 16.8 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 KLO19156.1 - 0.0074 16.0 0.6 0.025 14.3 0.3 1.8 1 1 0 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.17 KLO19156.1 - 0.13 11.6 0.1 0.27 10.5 0.0 1.6 2 0 0 2 2 2 0 RIO1 family NUDIX PF00293.23 KLO19157.1 - 3.6e-20 71.9 0.0 2.5e-13 49.8 0.0 2.3 2 0 0 2 2 2 2 NUDIX domain eIF-3c_N PF05470.7 KLO19158.1 - 5.2e-168 559.8 31.6 1.2e-166 555.3 21.9 2.1 1 1 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit 8 N-terminus PCI PF01399.22 KLO19158.1 - 2.1e-13 50.4 0.1 2.3e-12 47.1 0.0 2.8 2 0 0 2 2 2 1 PCI domain CENP-B_dimeris PF09026.5 KLO19158.1 - 0.024 14.8 7.3 0.077 13.2 5.1 1.8 1 0 0 1 1 1 0 Centromere protein B dimerisation domain ABC_tran PF00005.22 KLO19159.1 - 3.8e-64 215.0 0.0 3.7e-32 111.4 0.0 2.6 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 KLO19159.1 - 3.5e-60 203.7 32.8 5.4e-34 117.8 6.2 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.14 KLO19159.1 - 2.2e-17 63.0 0.1 7.7e-07 28.5 0.0 4.3 3 1 1 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 KLO19159.1 - 8.7e-16 58.7 0.0 0.0017 18.4 0.0 4.3 4 0 0 4 4 4 4 AAA domain AAA_17 PF13207.1 KLO19159.1 - 5.3e-11 43.4 0.0 7.2e-05 23.5 0.0 2.6 2 0 0 2 2 2 2 AAA domain ABC_ATPase PF09818.4 KLO19159.1 - 1.6e-10 40.1 0.1 0.00048 18.8 0.0 3.4 3 0 0 3 3 3 2 Predicted ATPase of the ABC class AAA_16 PF13191.1 KLO19159.1 - 7.1e-09 35.9 0.3 0.00013 22.0 0.0 3.0 3 0 0 3 3 2 2 AAA ATPase domain AAA_22 PF13401.1 KLO19159.1 - 9.2e-09 35.5 0.2 0.0064 16.6 0.0 3.7 3 2 0 3 3 2 2 AAA domain AAA_29 PF13555.1 KLO19159.1 - 1.3e-08 34.2 0.1 0.0043 16.5 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain IstB_IS21 PF01695.12 KLO19159.1 - 7.8e-08 31.9 0.1 1.1 8.6 0.0 4.3 4 0 0 4 4 4 2 IstB-like ATP binding protein AAA_33 PF13671.1 KLO19159.1 - 2.9e-06 27.2 0.1 0.13 12.1 0.0 3.1 2 2 0 2 2 2 2 AAA domain AAA_18 PF13238.1 KLO19159.1 - 4.4e-06 27.0 0.0 0.087 13.1 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_14 PF13173.1 KLO19159.1 - 5.5e-06 26.2 0.0 0.15 11.9 0.0 3.1 3 0 0 3 3 2 2 AAA domain DUF258 PF03193.11 KLO19159.1 - 5.6e-06 25.6 0.0 0.012 14.7 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_19 PF13245.1 KLO19159.1 - 7e-06 25.7 0.2 0.055 13.2 0.0 3.5 3 0 0 3 3 2 2 Part of AAA domain AAA_10 PF12846.2 KLO19159.1 - 8e-06 25.4 5.3 0.25 10.7 0.1 4.4 2 2 1 4 4 4 1 AAA-like domain AAA_30 PF13604.1 KLO19159.1 - 4.9e-05 22.9 0.0 0.12 11.9 0.0 3.3 3 1 0 3 3 3 1 AAA domain AAA_25 PF13481.1 KLO19159.1 - 5.8e-05 22.5 0.2 0.069 12.5 0.0 3.7 4 0 0 4 4 3 1 AAA domain AAA_5 PF07728.9 KLO19159.1 - 6.4e-05 22.7 0.2 0.45 10.2 0.0 3.5 4 0 0 4 4 3 2 AAA domain (dynein-related subfamily) AAA_28 PF13521.1 KLO19159.1 - 0.00023 21.1 0.7 0.48 10.3 0.1 2.8 2 1 0 2 2 2 2 AAA domain MobB PF03205.9 KLO19159.1 - 0.00067 19.3 0.1 1.6 8.4 0.0 2.8 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B DUF87 PF01935.12 KLO19159.1 - 0.00083 19.2 0.5 0.27 10.9 0.1 2.5 2 0 0 2 2 2 1 Domain of unknown function DUF87 PRK PF00485.13 KLO19159.1 - 0.00087 18.8 0.0 0.24 10.9 0.0 2.5 2 0 0 2 2 2 1 Phosphoribulokinase / Uridine kinase family RNA_helicase PF00910.17 KLO19159.1 - 0.0012 19.0 0.0 1.4 9.1 0.0 2.7 2 0 0 2 2 2 1 RNA helicase SbcCD_C PF13558.1 KLO19159.1 - 0.0012 18.7 2.9 1.9 8.4 0.0 3.9 4 1 0 4 4 2 2 Putative exonuclease SbcCD, C subunit CbiA PF01656.18 KLO19159.1 - 0.003 17.0 0.4 0.049 13.0 0.1 2.3 2 0 0 2 2 2 1 CobQ/CobB/MinD/ParA nucleotide binding domain G-alpha PF00503.15 KLO19159.1 - 0.0034 16.1 0.0 0.47 9.0 0.0 2.2 2 0 0 2 2 2 1 G-protein alpha subunit Zeta_toxin PF06414.7 KLO19159.1 - 0.0035 16.4 0.0 2.4 7.2 0.0 2.5 2 0 0 2 2 2 1 Zeta toxin Miro PF08477.8 KLO19159.1 - 0.0044 17.5 0.0 1.1 9.8 0.0 2.8 2 0 0 2 2 2 1 Miro-like protein FtsK_SpoIIIE PF01580.13 KLO19159.1 - 0.0045 16.4 0.0 2 7.8 0.0 2.5 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA_23 PF13476.1 KLO19159.1 - 0.0046 17.3 0.0 0.22 11.8 0.0 2.3 2 0 0 2 2 2 1 AAA domain SRP54 PF00448.17 KLO19159.1 - 0.0046 16.4 0.0 1.4 8.3 0.0 2.8 3 0 0 3 3 2 1 SRP54-type protein, GTPase domain AAA PF00004.24 KLO19159.1 - 0.0086 16.2 0.0 12 6.1 0.0 3.9 3 1 0 3 3 2 0 ATPase family associated with various cellular activities (AAA) Sigma54_activ_2 PF14532.1 KLO19159.1 - 0.0091 16.0 0.0 5.9 6.9 0.0 3.0 3 0 0 3 3 3 0 Sigma-54 interaction domain DUF2075 PF09848.4 KLO19159.1 - 0.014 14.4 0.0 7.4 5.4 0.0 2.8 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2075) NACHT PF05729.7 KLO19159.1 - 0.016 14.9 0.2 5.7 6.5 0.0 2.7 2 0 0 2 2 2 0 NACHT domain CoaE PF01121.15 KLO19159.1 - 0.016 14.6 0.4 2.2 7.6 0.0 3.0 3 0 0 3 3 3 0 Dephospho-CoA kinase Rad17 PF03215.10 KLO19159.1 - 0.019 13.7 0.0 1.8 7.1 0.0 2.2 2 0 0 2 2 2 0 Rad17 cell cycle checkpoint protein Mg_chelatase PF01078.16 KLO19159.1 - 0.027 13.6 0.0 8 5.5 0.0 2.5 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI DUF815 PF05673.8 KLO19159.1 - 0.036 12.9 0.0 1.1 8.0 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) APS_kinase PF01583.15 KLO19159.1 - 0.043 13.4 1.1 2.4 7.7 0.0 3.3 4 0 0 4 4 3 0 Adenylylsulphate kinase Viral_helicase1 PF01443.13 KLO19159.1 - 0.069 12.6 0.0 6.5 6.2 0.0 3.3 3 0 0 3 3 3 0 Viral (Superfamily 1) RNA helicase ATP_bind_1 PF03029.12 KLO19159.1 - 0.076 12.5 0.2 8.9 5.7 0.0 2.4 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein DUF3987 PF13148.1 KLO19159.1 - 0.08 11.4 0.0 3.7 6.0 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3987) KaiC PF06745.8 KLO19159.1 - 0.086 11.9 0.9 2.6 7.0 0.0 2.9 3 0 0 3 3 3 0 KaiC DUF1675 PF07897.6 KLO19159.1 - 0.12 12.1 0.8 0.22 11.3 0.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) NB-ARC PF00931.17 KLO19159.1 - 0.14 11.0 0.1 14 4.4 0.0 2.4 2 0 0 2 2 2 0 NB-ARC domain Septin PF00735.13 KLO19159.1 - 0.22 10.4 0.0 2 7.3 0.0 2.1 2 0 0 2 2 2 0 Septin Dyp_perox PF04261.7 KLO19160.1 - 1.6e-09 36.9 0.1 8.2e-07 28.0 0.0 2.9 3 1 0 3 3 3 2 Dyp-type peroxidase family LRR_4 PF12799.2 KLO19161.1 - 0.22 11.1 7.2 30 4.3 0.7 4.8 5 0 0 5 5 5 0 Leucine Rich repeats (2 copies) COesterase PF00135.23 KLO19162.1 - 3.8e-64 217.3 0.0 4.8e-64 216.9 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 KLO19162.1 - 7.9e-10 38.6 0.0 1.7e-09 37.5 0.0 1.6 1 0 0 1 1 1 1 alpha/beta hydrolase fold Epimerase PF01370.16 KLO19163.1 - 3.4e-21 75.7 0.2 4e-19 68.9 0.0 2.6 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 KLO19163.1 - 3.1e-14 52.3 0.0 5e-13 48.3 0.0 2.4 2 1 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 KLO19163.1 - 4.9e-12 45.3 0.0 1.7e-06 27.1 0.0 2.1 1 1 0 2 2 2 2 Male sterility protein NAD_binding_10 PF13460.1 KLO19163.1 - 2.9e-10 40.4 3.7 1.2e-09 38.4 2.6 2.2 1 1 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 KLO19163.1 - 4.3e-10 39.2 0.3 7.3e-09 35.2 0.4 2.1 2 0 0 2 2 2 1 NmrA-like family Polysacc_synt_2 PF02719.10 KLO19163.1 - 4.3e-06 25.8 0.3 1.1e-05 24.4 0.2 1.6 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein adh_short PF00106.20 KLO19163.1 - 0.00028 20.8 2.6 0.0014 18.5 1.8 2.2 1 1 0 1 1 1 1 short chain dehydrogenase DUF1138 PF06592.8 KLO19163.1 - 0.049 13.6 0.1 9.3 6.3 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1138) RmlD_sub_bind PF04321.12 KLO19163.1 - 0.085 11.7 0.7 0.36 9.6 0.0 2.3 3 1 0 3 3 3 0 RmlD substrate binding domain Epimerase PF01370.16 KLO19164.1 - 5.4e-23 81.6 0.1 1e-22 80.7 0.1 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 KLO19164.1 - 8.8e-14 50.8 0.4 5.9e-13 48.1 0.1 2.3 2 1 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 KLO19164.1 - 3e-12 46.0 0.1 2.9e-08 32.9 0.0 2.1 1 1 1 2 2 2 2 Male sterility protein NAD_binding_10 PF13460.1 KLO19164.1 - 4e-12 46.4 1.3 1.9e-11 44.2 0.9 2.1 1 1 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 KLO19164.1 - 1.2e-09 37.7 0.5 2.2e-09 36.9 0.3 1.4 1 0 0 1 1 1 1 NmrA-like family Polysacc_synt_2 PF02719.10 KLO19164.1 - 7.6e-08 31.5 0.1 2.1e-06 26.8 0.1 2.3 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.12 KLO19164.1 - 0.012 14.5 1.4 0.075 11.9 1.0 2.3 1 1 0 1 1 1 0 RmlD substrate binding domain adh_short PF00106.20 KLO19164.1 - 0.014 15.2 4.3 0.031 14.2 1.8 2.3 2 1 0 2 2 2 0 short chain dehydrogenase SRP40_C PF05022.7 KLO19165.1 - 1.3e-28 99.2 1.9 1.3e-28 99.2 1.3 2.6 2 0 0 2 2 2 1 SRP40, C-terminal domain DMRL_synthase PF00885.14 KLO19166.1 - 1.3e-47 161.0 0.4 3.8e-27 94.7 0.0 2.1 2 0 0 2 2 2 2 6,7-dimethyl-8-ribityllumazine synthase Ank PF00023.25 KLO19167.1 - 2.5e-14 52.2 0.1 6.4e-08 32.0 0.1 2.4 2 0 0 2 2 2 2 Ankyrin repeat Ank_2 PF12796.2 KLO19167.1 - 1.8e-13 50.6 0.0 2.7e-13 50.0 0.0 1.2 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.1 KLO19167.1 - 1.3e-10 41.1 0.3 4.6e-09 36.2 0.2 2.6 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_4 PF13637.1 KLO19167.1 - 1.8e-09 37.8 0.4 3.1e-05 24.3 0.1 3.1 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 KLO19167.1 - 3.9e-09 35.8 0.0 5.5e-05 23.0 0.0 2.5 2 0 0 2 2 2 2 Ankyrin repeat ATP_bind_3 PF01171.15 KLO19168.1 - 8.3e-45 152.5 0.0 1.2e-44 151.9 0.0 1.2 1 0 0 1 1 1 1 PP-loop family Asn_synthase PF00733.16 KLO19168.1 - 0.03 13.8 0.0 0.054 12.9 0.0 1.3 1 0 0 1 1 1 0 Asparagine synthase FAD_binding_3 PF01494.14 KLO19170.1 - 1.2e-18 67.3 0.4 4.3e-18 65.4 0.3 1.9 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 KLO19170.1 - 0.0021 18.0 0.2 0.0065 16.4 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.9 KLO19170.1 - 0.085 11.4 0.0 0.13 10.8 0.0 1.3 1 0 0 1 1 1 0 Tryptophan halogenase GMC_oxred_N PF00732.14 KLO19171.1 - 2.3e-46 158.3 0.0 7.4e-46 156.6 0.0 1.7 1 1 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 KLO19171.1 - 8.4e-30 103.9 0.0 1.4e-29 103.2 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.1 KLO19171.1 - 0.087 12.8 0.0 0.61 10.1 0.0 2.2 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain GATA PF00320.22 KLO19172.1 - 5.4 6.4 9.1 0.47 9.8 2.4 2.3 2 1 0 2 2 2 0 GATA zinc finger BTB PF00651.26 KLO19173.1 - 0.017 15.1 0.0 0.24 11.4 0.0 2.2 1 1 0 1 1 1 0 BTB/POZ domain CDC45 PF02724.9 KLO19173.1 - 0.18 9.7 8.7 0.25 9.3 6.0 1.1 1 0 0 1 1 1 0 CDC45-like protein Daxx PF03344.10 KLO19173.1 - 1.4 7.2 9.5 2 6.8 6.6 1.1 1 0 0 1 1 1 0 Daxx Family DUF2457 PF10446.4 KLO19173.1 - 8.1 5.0 20.5 12 4.4 14.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Nop14 PF04147.7 KLO19173.1 - 8.3 4.1 15.6 10 3.8 10.8 1.0 1 0 0 1 1 1 0 Nop14-like family WD40 PF00400.27 KLO19174.1 - 2.5e-78 255.3 18.3 1.8e-11 43.4 0.4 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat Nucleoporin_N PF08801.6 KLO19174.1 - 4.8e-07 28.8 1.3 0.056 12.1 0.1 4.7 1 1 4 5 5 5 3 Nup133 N terminal like Nup160 PF11715.3 KLO19174.1 - 9.7e-06 23.9 12.9 0.2 9.7 0.0 6.0 3 2 4 7 7 7 5 Nucleoporin Nup120/160 YTH PF04146.10 KLO19175.1 - 1.2e-45 154.5 0.1 2.1e-45 153.7 0.1 1.4 1 0 0 1 1 1 1 YT521-B-like domain MFS_1 PF07690.11 KLO19176.1 - 2.5e-20 72.4 31.7 3.1e-20 72.1 22.0 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_1 PF07690.11 KLO19177.1 - 8.5e-23 80.6 35.8 1.1e-22 80.2 24.8 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_1 PF07690.11 KLO19180.1 - 2.6e-54 184.2 41.2 4.5e-54 183.4 28.6 1.4 1 0 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.8 KLO19180.1 - 1.4e-16 59.8 16.1 1.8e-16 59.4 11.2 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 KLO19180.1 - 3.8e-15 55.4 12.7 3.8e-15 55.4 8.8 2.7 2 1 0 2 2 2 1 Sugar (and other) transporter MFS_2 PF13347.1 KLO19180.1 - 1.7e-07 29.9 4.0 1.7e-07 29.9 2.8 2.8 3 1 0 3 3 3 2 MFS/sugar transport protein TLC PF03219.9 KLO19180.1 - 0.03 12.7 0.2 0.1 11.0 0.0 1.9 2 0 0 2 2 2 0 TLC ATP/ADP transporter ATG22 PF11700.3 KLO19180.1 - 0.22 9.9 18.1 0.21 10.0 0.0 2.8 3 0 0 3 3 3 0 Vacuole effluxer Atg22 like 2TM PF13239.1 KLO19180.1 - 0.74 9.9 6.0 8.1 6.5 0.1 3.9 3 0 0 3 3 3 0 2TM domain DUF1948 PF09185.5 KLO19181.1 - 0.13 11.9 0.1 0.2 11.2 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1948) GMC_oxred_N PF00732.14 KLO19184.1 - 8.6e-68 228.6 0.0 1.1e-67 228.2 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 KLO19184.1 - 3e-35 121.6 0.0 5e-35 120.9 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 KLO19184.1 - 0.00088 18.2 0.1 0.0051 15.7 0.2 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KLO19184.1 - 0.0014 18.6 0.1 0.0031 17.5 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 KLO19184.1 - 0.0096 14.8 0.0 0.017 14.0 0.0 1.4 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox PF00070.22 KLO19184.1 - 0.0099 16.2 0.3 0.42 11.0 0.0 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 KLO19184.1 - 0.022 14.7 0.0 0.57 10.2 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 KLO19184.1 - 0.025 14.4 0.1 0.19 11.5 0.0 2.2 2 1 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase HHH PF00633.18 KLO19184.1 - 0.11 12.2 1.3 4.2 7.2 0.0 3.4 3 0 0 3 3 3 0 Helix-hairpin-helix motif FAD_binding_2 PF00890.19 KLO19184.1 - 0.17 10.7 0.0 0.28 9.9 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain Thi4 PF01946.12 KLO19184.1 - 0.17 10.9 0.0 0.32 10.0 0.0 1.3 1 0 0 1 1 1 0 Thi4 family GMC_oxred_N PF00732.14 KLO19185.1 - 6.1e-65 219.2 0.0 7.9e-65 218.9 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 KLO19185.1 - 2.6e-35 121.8 0.0 4.1e-35 121.1 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.19 KLO19185.1 - 5e-05 22.3 1.7 0.089 11.6 0.4 2.1 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.1 KLO19185.1 - 0.00012 21.9 0.5 0.00076 19.4 0.2 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 KLO19185.1 - 0.0005 19.0 0.1 0.00074 18.5 0.1 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein DAO PF01266.19 KLO19185.1 - 0.0024 16.8 0.1 0.017 14.0 0.0 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 KLO19185.1 - 0.0027 17.8 0.4 0.9 9.5 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 KLO19185.1 - 0.0037 16.3 0.3 0.006 15.7 0.2 1.3 1 0 0 1 1 1 1 Thi4 family Pyr_redox_2 PF07992.9 KLO19185.1 - 0.012 15.5 0.2 0.14 11.9 0.1 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 KLO19185.1 - 0.056 11.9 0.3 0.14 10.6 0.1 1.6 2 0 0 2 2 2 0 HI0933-like protein DUF3029 PF11230.3 KLO19186.1 - 0.12 10.5 0.0 0.15 10.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3029) DASH_Dad3 PF08656.5 KLO19188.1 - 5e-22 77.3 0.0 6.2e-22 77.0 0.0 1.1 1 0 0 1 1 1 1 DASH complex subunit Dad3 GMC_oxred_N PF00732.14 KLO19189.1 - 1.8e-66 224.3 0.0 2.2e-66 224.0 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 KLO19189.1 - 7.9e-35 120.2 0.0 1.3e-34 119.5 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.19 KLO19189.1 - 9.5e-05 21.4 0.5 0.04 12.7 0.2 2.2 2 0 0 2 2 2 2 FAD binding domain Pyr_redox_3 PF13738.1 KLO19189.1 - 0.00013 22.0 0.4 0.35 10.8 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 KLO19189.1 - 0.00019 20.4 0.1 0.00029 19.8 0.1 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein DAO PF01266.19 KLO19189.1 - 0.00024 20.1 0.1 0.0027 16.6 0.0 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KLO19189.1 - 0.00044 20.2 0.1 0.0013 18.6 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 KLO19189.1 - 0.001 19.0 0.1 0.12 12.2 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 KLO19189.1 - 0.027 13.5 0.1 0.047 12.7 0.1 1.3 1 0 0 1 1 1 0 Thi4 family GMC_oxred_N PF00732.14 KLO19190.1 - 2.3e-62 210.8 0.0 4e-62 210.0 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 KLO19190.1 - 7e-35 120.4 0.0 1.3e-34 119.5 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.1 KLO19190.1 - 2.6e-05 24.1 0.1 6.4e-05 22.9 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 KLO19190.1 - 0.00015 20.7 1.1 0.00098 18.1 0.5 2.0 2 0 0 2 2 2 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 KLO19190.1 - 0.00024 20.1 0.1 0.0004 19.4 0.1 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_binding_2 PF00890.19 KLO19190.1 - 0.00039 19.4 0.2 0.0024 16.8 0.2 2.1 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.9 KLO19190.1 - 0.002 18.0 0.3 0.0078 16.1 0.1 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 KLO19190.1 - 0.01 14.3 0.1 0.018 13.5 0.1 1.3 1 0 0 1 1 1 0 HI0933-like protein GIDA PF01134.17 KLO19190.1 - 0.028 13.2 0.4 5.4 5.7 0.0 2.2 2 0 0 2 2 2 0 Glucose inhibited division protein A Thi4 PF01946.12 KLO19190.1 - 0.11 11.5 0.1 0.21 10.6 0.0 1.4 1 0 0 1 1 1 0 Thi4 family NAD_binding_9 PF13454.1 KLO19190.1 - 0.14 11.8 0.3 0.28 10.9 0.2 1.5 1 0 0 1 1 1 0 FAD-NAD(P)-binding FAD_binding_3 PF01494.14 KLO19190.1 - 0.19 10.7 0.4 0.7 8.8 0.1 1.9 2 0 0 2 2 2 0 FAD binding domain Trp_halogenase PF04820.9 KLO19190.1 - 0.25 9.9 1.5 0.41 9.2 0.1 2.0 3 0 0 3 3 3 0 Tryptophan halogenase MFS_1 PF07690.11 KLO19191.1 - 1.6e-22 79.7 33.3 2.5e-22 79.0 23.1 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily Methyltrans_Mon PF14314.1 KLO19192.1 - 0.028 12.2 0.0 0.039 11.7 0.0 1.2 1 0 0 1 1 1 0 Virus-capping methyltransferase MH2 PF03166.9 KLO19192.1 - 0.064 13.0 0.0 0.1 12.4 0.0 1.2 1 0 0 1 1 1 0 MH2 domain NAD_binding_4 PF07993.7 KLO19193.1 - 1e-31 109.8 0.0 2.1e-31 108.7 0.0 1.5 2 0 0 2 2 2 1 Male sterility protein AMP-binding PF00501.23 KLO19193.1 - 1.5e-30 105.9 0.1 3.3e-28 98.2 0.0 2.9 2 1 0 2 2 2 2 AMP-binding enzyme Epimerase PF01370.16 KLO19193.1 - 6.8e-09 35.5 0.0 1.3e-08 34.6 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short PF00106.20 KLO19193.1 - 0.0083 16.0 3.3 0.078 12.8 0.0 3.5 4 0 0 4 4 4 1 short chain dehydrogenase 3Beta_HSD PF01073.14 KLO19193.1 - 0.016 13.9 0.0 0.055 12.1 0.0 1.8 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Semialdhyde_dh PF01118.19 KLO19193.1 - 0.033 14.4 0.0 0.13 12.6 0.0 2.0 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain Dimerisation PF08100.6 KLO19193.1 - 0.046 13.5 0.1 0.15 11.9 0.1 2.0 1 0 0 1 1 1 0 Dimerisation domain KR PF08659.5 KLO19193.1 - 0.048 13.3 0.2 0.2 11.3 0.0 2.1 2 0 0 2 2 2 0 KR domain GMC_oxred_N PF00732.14 KLO19194.1 - 2.5e-59 200.8 0.0 4.5e-59 200.0 0.0 1.4 2 0 0 2 2 2 1 GMC oxidoreductase GMC_oxred_C PF05199.8 KLO19194.1 - 8.7e-35 120.1 0.0 1.5e-34 119.3 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 KLO19194.1 - 3.2e-05 23.0 0.9 0.00012 21.1 0.6 1.9 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KLO19194.1 - 0.0001 22.2 0.4 0.00026 20.9 0.3 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 KLO19194.1 - 0.00018 20.5 0.1 0.0003 19.8 0.1 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_binding_2 PF00890.19 KLO19194.1 - 0.00026 19.9 0.2 0.00046 19.1 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 KLO19194.1 - 0.0037 17.1 0.2 0.011 15.6 0.1 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 KLO19194.1 - 0.01 14.3 0.1 0.038 12.4 0.1 1.9 3 0 0 3 3 3 0 HI0933-like protein Pyr_redox_3 PF13738.1 KLO19194.1 - 0.022 14.8 0.3 0.13 12.2 0.3 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 KLO19194.1 - 0.069 12.9 0.3 0.14 11.9 0.2 1.4 1 0 0 1 1 1 0 FAD-NAD(P)-binding K_oxygenase PF13434.1 KLO19194.1 - 0.099 11.5 0.0 0.16 10.8 0.0 1.2 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) Thi4 PF01946.12 KLO19194.1 - 0.11 11.5 0.1 0.2 10.7 0.1 1.3 1 0 0 1 1 1 0 Thi4 family GIDA PF01134.17 KLO19194.1 - 0.16 10.7 0.2 6.1 5.5 0.0 2.1 2 0 0 2 2 2 0 Glucose inhibited division protein A GMC_oxred_N PF00732.14 KLO19195.1 - 6.2e-55 186.4 0.0 8.5e-55 185.9 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 KLO19195.1 - 3.4e-33 114.9 0.0 6.5e-33 114.0 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 KLO19195.1 - 4.1e-07 29.2 0.0 2.8e-06 26.4 0.0 2.0 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 KLO19195.1 - 7.1e-06 26.0 0.1 8e-05 22.6 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 KLO19195.1 - 1.3e-05 25.3 0.1 0.046 13.7 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 KLO19195.1 - 8.5e-05 21.6 0.1 0.00012 21.0 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_binding_2 PF00890.19 KLO19195.1 - 0.00016 20.6 0.1 0.00035 19.5 0.1 1.5 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 KLO19195.1 - 0.00046 20.1 0.3 0.00097 19.1 0.2 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.9 KLO19195.1 - 0.0013 17.2 0.0 0.0024 16.4 0.0 1.4 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox PF00070.22 KLO19195.1 - 0.0023 18.2 0.4 0.6 10.5 0.1 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 KLO19195.1 - 0.0028 16.7 0.1 0.0048 16.0 0.1 1.3 1 0 0 1 1 1 1 Thi4 family FAD_oxidored PF12831.2 KLO19195.1 - 0.0049 15.9 0.2 0.014 14.4 0.2 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 KLO19195.1 - 0.018 14.7 0.2 0.034 13.9 0.1 1.4 1 0 0 1 1 1 0 FAD-NAD(P)-binding Trp_halogenase PF04820.9 KLO19195.1 - 0.051 12.2 0.2 0.073 11.6 0.1 1.2 1 0 0 1 1 1 0 Tryptophan halogenase GIDA PF01134.17 KLO19195.1 - 0.057 12.2 0.4 0.12 11.1 0.0 1.7 2 0 0 2 2 2 0 Glucose inhibited division protein A WD40 PF00400.27 KLO19196.1 - 3.4e-20 71.0 15.5 8.5e-09 34.9 0.1 6.0 6 0 0 6 6 6 4 WD domain, G-beta repeat Rax2 PF12768.2 KLO19196.1 - 0.00016 20.9 0.1 0.0013 17.9 0.0 2.2 2 0 0 2 2 2 1 Cortical protein marker for cell polarity DPPIV_N PF00930.16 KLO19196.1 - 0.0003 19.4 0.4 0.032 12.8 0.1 3.0 2 1 0 3 3 3 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Apc4_WD40 PF12894.2 KLO19196.1 - 0.0012 18.2 0.1 30 4.2 0.0 4.5 5 0 0 5 5 5 0 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.6 KLO19196.1 - 0.018 14.7 0.3 0.9 9.2 0.0 2.9 2 1 0 2 2 2 0 Eukaryotic translation initiation factor eIF2A zf-MYND PF01753.13 KLO19197.1 - 7.1e-10 38.5 9.9 2.2e-09 37.0 6.8 1.9 1 0 0 1 1 1 1 MYND finger FAA_hydrolase PF01557.13 KLO19198.1 - 6.4e-56 189.2 0.0 8.1e-56 188.9 0.0 1.0 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family KH_2 PF07650.12 KLO19198.1 - 0.07 12.6 0.6 0.15 11.6 0.0 1.8 2 0 0 2 2 2 0 KH domain DsrH PF04077.7 KLO19198.1 - 0.071 12.7 0.0 0.14 11.8 0.0 1.4 1 0 0 1 1 1 0 DsrH like protein SAPS PF04499.10 KLO19199.1 - 3.8e-93 312.7 0.0 4.9e-93 312.3 0.0 1.1 1 0 0 1 1 1 1 SIT4 phosphatase-associated protein ChlamPMP_M PF07548.6 KLO19199.1 - 0.031 14.0 0.0 0.22 11.2 0.0 2.1 2 0 0 2 2 2 0 Chlamydia polymorphic membrane protein middle domain DnaB_bind PF10410.4 KLO19199.1 - 0.065 13.2 0.1 0.34 10.9 0.0 2.3 2 0 0 2 2 2 0 DnaB-helicase binding domain of primase Adap_comp_sub PF00928.16 KLO19200.1 - 1.3e-87 293.2 0.0 1.7e-87 292.8 0.0 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.15 KLO19200.1 - 1.5e-06 27.9 1.7 3.1e-06 26.9 1.2 1.5 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Lipase_GDSL PF00657.17 KLO19201.1 - 4.4e-14 52.8 0.2 5e-14 52.6 0.1 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase DUF572 PF04502.8 KLO19202.1 - 8.6e-90 301.2 10.2 1.1e-89 300.9 7.0 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF572) HrpA_pilin PF09589.5 KLO19202.1 - 0.018 15.4 1.2 0.022 15.1 0.1 1.7 2 0 0 2 2 2 0 HrpA pilus formation protein zf-FCS PF06467.9 KLO19202.1 - 0.019 14.5 1.1 0.39 10.4 0.1 2.3 2 0 0 2 2 2 0 MYM-type Zinc finger with FCS sequence motif DUF866 PF05907.8 KLO19202.1 - 0.022 14.2 0.1 0.05 13.0 0.1 1.6 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF866) FinO_N PF12602.3 KLO19202.1 - 0.079 13.2 2.2 1 9.6 0.9 3.0 2 1 0 2 2 2 0 Fertility inhibition protein N terminal Lar_restr_allev PF14354.1 KLO19202.1 - 0.12 12.7 0.6 8.5 6.7 1.2 2.5 1 1 1 2 2 2 0 Restriction alleviation protein Lar PI3_PI4_kinase PF00454.22 KLO19203.1 - 2e-35 122.3 0.0 1.3e-34 119.6 0.0 2.2 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.15 KLO19203.1 - 3.4e-19 68.7 0.0 1e-18 67.1 0.0 1.8 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) RdRP PF05183.7 KLO19204.1 - 1.6e-143 479.4 0.0 2.2e-143 479.0 0.0 1.1 1 0 0 1 1 1 1 RNA dependent RNA polymerase Sybindin PF04099.7 KLO19205.1 - 1.6e-38 131.5 0.0 1.9e-38 131.4 0.0 1.0 1 0 0 1 1 1 1 Sybindin-like family Sedlin_N PF04628.8 KLO19205.1 - 9.4e-10 38.4 0.0 9.6e-10 38.4 0.0 1.1 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region Peptidase_M28 PF04389.12 KLO19206.1 - 1.9e-35 122.2 1.0 2.9e-35 121.5 0.1 1.7 2 0 0 2 2 2 1 Peptidase family M28 PKK PF12474.3 KLO19207.1 - 0.06 13.0 0.1 0.06 13.0 0.1 2.3 1 1 1 2 2 2 0 Polo kinase kinase DUF964 PF06133.6 KLO19207.1 - 0.23 11.4 7.3 0.097 12.6 1.9 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF964) ATP-synt_B PF00430.13 KLO19207.1 - 0.51 10.1 10.2 0.091 12.5 2.7 2.3 2 0 0 2 2 2 0 ATP synthase B/B' CF(0) HeLo PF14479.1 KLO19207.1 - 1 9.0 7.1 0.22 11.2 2.0 1.9 1 1 1 2 2 2 0 Prion-inhibition and propagation Spt5_N PF11942.3 KLO19207.1 - 1.5 9.4 8.8 6 7.5 0.8 2.5 2 1 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal DUF947 PF06102.7 KLO19207.1 - 2.7 7.8 8.1 0.83 9.4 0.6 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF947) DivIVA PF05103.8 KLO19207.1 - 4.4 7.3 10.8 0.53 10.3 2.8 2.3 1 1 1 2 2 2 0 DivIVA protein Methyltransf_32 PF13679.1 KLO19208.1 - 7.9e-23 80.7 0.5 1.8e-22 79.5 0.3 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KLO19208.1 - 0.00034 20.2 0.0 0.00066 19.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KLO19208.1 - 0.019 14.3 0.0 0.038 13.3 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_18 PF12847.2 KLO19208.1 - 0.025 15.1 0.0 0.072 13.6 0.0 1.9 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.7 KLO19208.1 - 0.078 13.4 0.3 0.23 11.9 0.0 2.1 2 0 0 2 2 2 0 Methyltransferase domain MerR-DNA-bind PF09278.6 KLO19208.1 - 0.089 13.2 0.1 0.23 11.8 0.1 1.7 1 0 0 1 1 1 0 MerR, DNA binding NAD_binding_10 PF13460.1 KLO19209.1 - 2.2e-29 102.7 0.0 2.7e-29 102.4 0.0 1.1 1 0 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 KLO19209.1 - 0.00028 20.2 0.1 0.0005 19.3 0.1 1.4 1 0 0 1 1 1 1 NmrA-like family ADH_zinc_N PF00107.21 KLO19209.1 - 0.0032 17.0 0.1 0.019 14.5 0.0 2.0 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Ldh_1_N PF00056.18 KLO19209.1 - 0.0033 17.2 0.2 0.0052 16.6 0.2 1.4 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Semialdhyde_dh PF01118.19 KLO19209.1 - 0.0059 16.8 0.1 0.01 16.1 0.1 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Epimerase PF01370.16 KLO19209.1 - 0.015 14.7 0.0 0.023 14.1 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family TPP_enzyme_N PF02776.13 KLO19210.1 - 9.2e-58 194.5 0.1 2.2e-56 190.0 0.0 2.3 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.16 KLO19210.1 - 9.3e-48 161.6 0.3 6.2e-46 155.7 0.2 2.6 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.17 KLO19210.1 - 1e-35 122.4 0.5 3.1e-35 120.9 0.1 2.1 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain DUF3571 PF12095.3 KLO19211.1 - 0.0096 16.1 0.2 4.4 7.6 0.1 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF3571) His_Phos_1 PF00300.17 KLO19212.1 - 3.6e-26 92.1 0.1 1.1e-25 90.6 0.0 1.7 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) LysR_substrate PF03466.15 KLO19212.1 - 0.0017 17.5 0.0 0.004 16.2 0.0 1.5 2 0 0 2 2 2 1 LysR substrate binding domain CBF PF03914.12 KLO19213.1 - 5.2e-36 123.5 0.0 5.2e-36 123.5 0.0 3.8 3 2 0 3 3 3 1 CBF/Mak21 family TFIIA PF03153.8 KLO19213.1 - 0.0016 18.4 15.7 0.0016 18.4 10.9 3.8 3 1 1 4 4 4 1 Transcription factor IIA, alpha/beta subunit Adaptin_N PF01602.15 KLO19213.1 - 0.0084 14.4 0.1 0.06 11.6 0.0 2.0 2 0 0 2 2 2 1 Adaptin N terminal region WD40 PF00400.27 KLO19214.1 - 8.3e-44 145.9 15.0 2.5e-08 33.4 0.1 7.5 7 0 0 7 7 7 7 WD domain, G-beta repeat PFU PF09070.6 KLO19214.1 - 2.6e-40 137.0 0.1 4.9e-40 136.1 0.1 1.5 1 0 0 1 1 1 1 PFU (PLAA family ubiquitin binding) PUL PF08324.6 KLO19214.1 - 2e-31 108.7 0.0 2.7e-31 108.3 0.0 1.2 1 0 0 1 1 1 1 PUL domain BBS2_Mid PF14783.1 KLO19214.1 - 0.00023 20.9 0.0 0.57 9.9 0.0 3.2 2 1 3 5 5 5 3 Ciliary BBSome complex subunit 2, middle region HORMA PF02301.13 KLO19215.1 - 4e-43 147.3 0.1 8.9e-43 146.1 0.0 1.6 2 0 0 2 2 2 1 HORMA domain PHD PF00628.24 KLO19215.1 - 2.2e-08 33.6 7.6 3.7e-08 32.9 5.3 1.4 1 0 0 1 1 1 1 PHD-finger zf-PHD-like PF15446.1 KLO19215.1 - 0.0026 17.0 0.1 0.0081 15.4 0.1 1.8 1 0 0 1 1 1 1 PHD/FYVE-zinc-finger like domain Prok-RING_1 PF14446.1 KLO19215.1 - 0.0034 17.0 2.8 0.0066 16.1 1.9 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 1 PHD_2 PF13831.1 KLO19215.1 - 0.95 8.8 3.5 1.7 8.0 2.4 1.4 1 0 0 1 1 1 0 PHD-finger PigN PF04987.9 KLO19216.1 - 6.9e-103 344.6 20.9 8.9e-103 344.2 14.5 1.1 1 0 0 1 1 1 1 Phosphatidylinositolglycan class N (PIG-N) Phosphodiest PF01663.17 KLO19216.1 - 4.5e-11 42.6 0.0 4.9e-08 32.7 0.0 2.3 1 1 1 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.18 KLO19216.1 - 1.8e-06 27.3 0.2 2.6e-06 26.8 0.1 1.2 1 0 0 1 1 1 1 Sulfatase Metalloenzyme PF01676.13 KLO19216.1 - 0.00058 19.3 0.0 0.00097 18.5 0.0 1.2 1 0 0 1 1 1 1 Metalloenzyme superfamily DEPP PF15343.1 KLO19216.1 - 0.27 10.8 0.1 0.46 10.0 0.1 1.3 1 0 0 1 1 1 0 Decidual protein induced by progesterone family Na_Ca_ex PF01699.19 KLO19217.1 - 1.8e-41 141.0 29.4 5.6e-23 81.1 7.8 3.3 2 1 1 3 3 3 2 Sodium/calcium exchanger protein DUF872 PF05915.7 KLO19217.1 - 0.00091 19.0 0.6 0.29 10.9 0.3 2.8 2 0 0 2 2 2 2 Eukaryotic protein of unknown function (DUF872) Methyltransf_25 PF13649.1 KLO19218.1 - 1.1e-08 35.3 0.0 9.8e-08 32.2 0.0 2.4 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 KLO19218.1 - 0.0087 15.7 0.0 0.013 15.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KLO19218.1 - 0.01 16.2 0.0 0.98 9.9 0.0 2.6 2 1 0 2 2 2 0 Methyltransferase domain Methyltransf_12 PF08242.7 KLO19218.1 - 0.08 13.4 0.0 0.33 11.4 0.0 2.0 1 1 0 1 1 1 0 Methyltransferase domain DUF4309 PF14172.1 KLO19219.1 - 0.00021 21.2 17.6 7.6 6.5 0.2 6.9 1 1 5 6 6 6 4 Domain of unknown function (DUF4309) DUF2136 PF09907.4 KLO19219.1 - 0.11 12.6 15.5 29 4.8 0.1 5.7 1 1 4 6 6 6 0 Uncharacterized protein conserved in bacteria (DUF2136) 3D PF06725.6 KLO19219.1 - 3.5 7.6 13.7 89 3.1 0.1 6.4 1 1 9 10 10 10 0 3D domain Gtr1_RagA PF04670.7 KLO19220.1 - 7.1e-87 290.3 0.0 9.7e-87 289.9 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Ras PF00071.17 KLO19220.1 - 2.1e-08 33.7 0.0 3.6e-08 32.9 0.0 1.4 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KLO19220.1 - 1.6e-07 31.7 0.0 4e-07 30.5 0.0 1.7 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KLO19220.1 - 8.1e-07 28.4 0.0 1.4e-06 27.7 0.0 1.4 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 KLO19220.1 - 4.8e-06 26.5 0.0 1.3e-05 25.1 0.0 1.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase SRPRB PF09439.5 KLO19220.1 - 0.016 14.4 0.0 0.026 13.7 0.0 1.4 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit PduV-EutP PF10662.4 KLO19220.1 - 0.017 14.5 0.0 0.083 12.3 0.0 2.0 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation tRNA-synt_1 PF00133.17 KLO19220.1 - 0.06 11.3 0.0 0.084 10.8 0.0 1.1 1 0 0 1 1 1 0 tRNA synthetases class I (I, L, M and V) AAA_29 PF13555.1 KLO19220.1 - 0.081 12.4 0.3 0.18 11.3 0.2 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain RuvB_N PF05496.7 KLO19220.1 - 0.097 11.7 0.0 0.19 10.7 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus DUF1674 PF07896.7 KLO19220.1 - 0.11 12.7 0.1 0.21 11.8 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1674) CwfJ_C_1 PF04677.10 KLO19221.1 - 2.6e-26 91.6 0.0 4.4e-26 90.9 0.0 1.4 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 CwfJ_C_2 PF04676.9 KLO19221.1 - 2.3e-24 85.7 0.0 4.5e-24 84.7 0.0 1.4 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 2 zf-CCHC_2 PF13696.1 KLO19221.1 - 6.8e-16 57.4 11.6 5e-06 25.9 0.3 3.5 2 1 1 3 3 3 3 Zinc knuckle zf-CCHC PF00098.18 KLO19221.1 - 7.8e-06 25.5 12.6 0.0025 17.6 0.1 3.9 4 0 0 4 4 4 2 Zinc knuckle eIF3g PF12353.3 KLO19221.1 - 0.00031 20.6 10.9 0.011 15.6 0.8 3.3 2 1 1 3 3 3 2 Eukaryotic translation initiation factor 3 subunit G DCX PF03607.12 KLO19221.1 - 0.13 11.8 0.0 0.54 9.8 0.0 2.0 2 0 0 2 2 2 0 Doublecortin TNFR_c6 PF00020.13 KLO19221.1 - 0.17 11.9 11.5 3.9 7.6 0.8 3.7 3 0 0 3 3 3 0 TNFR/NGFR cysteine-rich region zinc-ribbons_6 PF07191.7 KLO19221.1 - 4.9 7.0 8.7 21 4.9 0.1 3.3 2 1 1 3 3 3 0 zinc-ribbons Aminotran_1_2 PF00155.16 KLO19222.1 - 8.5e-32 110.4 0.0 1e-31 110.2 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Arginase PF00491.16 KLO19223.1 - 4.1e-79 265.7 0.2 4.8e-79 265.5 0.2 1.0 1 0 0 1 1 1 1 Arginase family DHBP_synthase PF00926.14 KLO19224.1 - 2.3e-77 258.6 0.1 2.6e-77 258.4 0.0 1.0 1 0 0 1 1 1 1 3,4-dihydroxy-2-butanone 4-phosphate synthase Zn_clus PF00172.13 KLO19225.1 - 9.9e-07 28.5 13.1 1.5e-06 27.9 9.1 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Acyl-CoA_dh_1 PF00441.19 KLO19226.1 - 7.5e-44 149.4 0.2 1.5e-43 148.4 0.2 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 KLO19226.1 - 2.1e-35 121.7 0.0 3.8e-35 120.8 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.14 KLO19226.1 - 2.1e-17 62.3 0.0 4.3e-17 61.3 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.6 KLO19226.1 - 1.4e-16 61.0 0.0 2.4e-16 60.1 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain HpaB_N PF11794.3 KLO19226.1 - 0.013 14.9 0.2 0.058 12.7 0.1 1.9 1 1 0 1 1 1 0 4-hydroxyphenylacetate 3-hydroxylase N terminal Acyl-CoA_ox_N PF14749.1 KLO19226.1 - 0.063 13.5 0.0 0.23 11.7 0.0 1.9 2 0 0 2 2 2 0 Acyl-coenzyme A oxidase N-terminal LRR_4 PF12799.2 KLO19227.1 - 0.008 15.7 10.2 6.1 6.5 0.0 6.8 4 3 1 5 5 5 2 Leucine Rich repeats (2 copies) Ins_P5_2-kin PF06090.7 KLO19228.1 - 2.3e-46 158.3 0.0 2.7e-46 158.0 0.0 1.1 1 0 0 1 1 1 1 Inositol-pentakisphosphate 2-kinase Kinesin PF00225.18 KLO19229.1 - 2.5e-99 332.1 1.5 7.4e-55 185.9 0.0 3.4 3 0 0 3 3 3 2 Kinesin motor domain IncA PF04156.9 KLO19229.1 - 0.0027 17.3 12.6 0.0027 17.3 8.7 12.5 5 2 6 11 11 11 7 IncA protein adh_short PF00106.20 KLO19230.1 - 1.5e-31 109.5 0.5 2.1e-31 109.0 0.3 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KLO19230.1 - 8.5e-31 107.5 0.1 1e-30 107.2 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KLO19230.1 - 4.6e-17 62.2 0.2 7.2e-17 61.6 0.1 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 KLO19230.1 - 2.7e-07 30.2 0.0 3.7e-07 29.8 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 KLO19230.1 - 4.9e-07 28.9 0.0 6.1e-07 28.6 0.0 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.14 KLO19230.1 - 0.0024 16.6 0.0 0.0034 16.1 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Abhydrolase_6 PF12697.2 KLO19231.1 - 2.6e-24 86.3 0.0 3.2e-24 86.1 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KLO19231.1 - 6.4e-11 42.1 0.0 7.1e-11 42.0 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KLO19231.1 - 4.6e-10 39.4 0.0 6.3e-10 38.9 0.0 1.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold Chlorophyllase PF07224.6 KLO19231.1 - 5.8e-07 28.5 0.0 8.5e-07 28.0 0.0 1.1 1 0 0 1 1 1 1 Chlorophyllase Chlorophyllase2 PF12740.2 KLO19231.1 - 1.1e-05 24.5 0.0 1.7e-05 23.8 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase enzyme Hydrolase_4 PF12146.3 KLO19231.1 - 0.00054 19.7 0.0 0.00093 19.0 0.0 1.5 1 0 0 1 1 1 1 Putative lysophospholipase Methyltransf_25 PF13649.1 KLO19232.1 - 8.1e-08 32.5 0.0 1.9e-06 28.1 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KLO19232.1 - 0.022 14.7 0.0 0.038 14.0 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain GATA PF00320.22 KLO19234.1 - 1.1e-12 47.0 6.5 2.8e-12 45.7 4.5 1.7 1 0 0 1 1 1 1 GATA zinc finger PAS PF00989.19 KLO19234.1 - 0.00011 21.9 0.0 0.00021 21.0 0.0 1.4 1 0 0 1 1 1 1 PAS fold PAS_9 PF13426.1 KLO19234.1 - 0.00042 20.6 0.0 0.00073 19.8 0.0 1.4 1 0 0 1 1 1 1 PAS domain PAS_4 PF08448.5 KLO19234.1 - 0.015 15.3 0.0 0.03 14.3 0.0 1.5 1 0 0 1 1 1 0 PAS fold p450 PF00067.17 KLO19235.1 - 2.6e-74 250.4 0.0 3.3e-74 250.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 KLO19236.1 - 6.5e-75 252.4 0.0 8.6e-75 252.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 tRNA_Me_trans PF03054.11 KLO19237.1 - 1.3e-101 339.7 0.0 1.4e-101 339.5 0.0 1.0 1 0 0 1 1 1 1 tRNA methyl transferase UPF1_Zn_bind PF09416.5 KLO19238.1 - 2e-69 231.9 2.6 2e-69 231.9 1.8 2.0 2 0 0 2 2 2 1 RNA helicase (UPF2 interacting domain) AAA_12 PF13087.1 KLO19238.1 - 3e-58 196.5 0.0 5.6e-58 195.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 KLO19238.1 - 7.5e-43 146.7 2.5 1.6e-42 145.7 1.7 1.6 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 KLO19238.1 - 5.2e-14 51.7 1.2 1.2e-13 50.6 0.2 2.1 2 0 0 2 2 2 1 Part of AAA domain AAA_30 PF13604.1 KLO19238.1 - 9.3e-12 44.9 2.4 2e-09 37.2 0.2 2.6 2 0 0 2 2 2 2 AAA domain ResIII PF04851.10 KLO19238.1 - 1.4e-08 34.7 0.0 2.9e-08 33.7 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DUF2075 PF09848.4 KLO19238.1 - 3.1e-08 32.9 0.0 5.9e-07 28.7 0.0 2.8 3 1 0 3 3 3 1 Uncharacterized conserved protein (DUF2075) Helicase_RecD PF05127.9 KLO19238.1 - 7.4e-05 22.4 0.4 0.0002 21.0 0.3 1.8 1 1 0 1 1 1 1 Helicase Viral_helicase1 PF01443.13 KLO19238.1 - 0.00019 21.0 0.2 0.15 11.5 0.0 3.5 3 1 0 3 3 3 1 Viral (Superfamily 1) RNA helicase DEAD PF00270.24 KLO19238.1 - 0.008 15.6 0.7 0.017 14.6 0.5 1.6 1 1 0 1 1 1 1 DEAD/DEAH box helicase PIF1 PF05970.9 KLO19238.1 - 0.011 14.7 0.1 0.76 8.6 0.0 2.2 2 0 0 2 2 2 0 PIF1-like helicase SRP54 PF00448.17 KLO19238.1 - 0.011 15.1 0.1 0.021 14.2 0.1 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain Ribosomal_S13_N PF08069.7 KLO19238.1 - 0.013 15.3 0.0 0.059 13.2 0.0 2.1 2 0 0 2 2 2 0 Ribosomal S13/S15 N-terminal domain KaiC PF06745.8 KLO19238.1 - 0.017 14.2 0.1 0.1 11.7 0.0 2.2 2 1 0 2 2 2 0 KaiC AAA_25 PF13481.1 KLO19238.1 - 0.019 14.3 0.0 0.037 13.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.1 KLO19238.1 - 0.02 14.8 0.1 0.046 13.6 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.1 KLO19238.1 - 0.022 14.9 0.2 0.12 12.4 0.1 2.2 1 1 0 1 1 1 0 AAA domain PhoH PF02562.11 KLO19238.1 - 0.045 12.9 0.1 0.094 11.9 0.1 1.5 1 0 0 1 1 1 0 PhoH-like protein AAA_10 PF12846.2 KLO19238.1 - 0.059 12.7 0.0 0.15 11.4 0.0 1.7 1 1 1 2 2 2 0 AAA-like domain AAA PF00004.24 KLO19238.1 - 0.084 13.0 0.2 0.2 11.8 0.2 1.8 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 KLO19238.1 - 0.11 12.2 0.0 0.24 11.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) HSP20 PF00011.16 KLO19239.1 - 2.1e-16 59.6 0.1 7.4e-16 57.8 0.0 1.7 1 1 0 1 1 1 1 Hsp20/alpha crystallin family CdhC PF03598.10 KLO19239.1 - 0.032 12.7 0.0 0.04 12.3 0.0 1.1 1 0 0 1 1 1 0 CO dehydrogenase/acetyl-CoA synthase complex beta subunit GvpH PF05455.6 KLO19239.1 - 0.089 12.4 0.0 0.14 11.7 0.0 1.3 1 0 0 1 1 1 0 GvpH Abhydrolase_6 PF12697.2 KLO19240.1 - 1.1e-15 58.1 0.4 1.4e-15 57.8 0.3 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KLO19240.1 - 0.0013 18.4 0.0 0.0034 17.1 0.0 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family p450 PF00067.17 KLO19241.1 - 5.4e-73 246.0 0.0 7.1e-73 245.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 MFS_1 PF07690.11 KLO19242.1 - 1e-22 80.3 83.5 1e-16 60.6 34.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.2 KLO19242.1 - 0.11 12.3 7.7 2.8 7.7 4.3 2.8 2 0 0 2 2 2 0 MFS_1 like family CENP-C_C PF11699.3 KLO19245.1 - 5.1e-26 90.4 0.2 8.9e-26 89.7 0.1 1.4 1 0 0 1 1 1 1 Mif2/CENP-C like Cupin_2 PF07883.6 KLO19245.1 - 2.6e-05 23.6 0.0 7.8e-05 22.1 0.0 1.8 2 0 0 2 2 2 1 Cupin domain AraC_binding PF02311.14 KLO19245.1 - 0.049 13.3 0.0 0.096 12.3 0.0 1.4 1 0 0 1 1 1 0 AraC-like ligand binding domain HSP20 PF00011.16 KLO19246.1 - 2.8e-15 56.0 0.1 3.5e-09 36.4 0.0 2.2 2 0 0 2 2 2 2 Hsp20/alpha crystallin family CdhC PF03598.10 KLO19246.1 - 0.042 12.3 0.0 0.057 11.8 0.0 1.1 1 0 0 1 1 1 0 CO dehydrogenase/acetyl-CoA synthase complex beta subunit GvpH PF05455.6 KLO19246.1 - 0.053 13.1 0.0 0.1 12.2 0.0 1.5 1 0 0 1 1 1 0 GvpH SKIP_SNW PF02731.10 KLO19247.1 - 1.4e-66 222.8 1.4 1.4e-66 222.8 1.0 2.8 3 0 0 3 3 3 1 SKIP/SNW domain Myc_N PF01056.13 KLO19247.1 - 0.27 10.3 5.6 0.57 9.2 3.9 1.5 1 0 0 1 1 1 0 Myc amino-terminal region Spt5_N PF11942.3 KLO19247.1 - 6.1 7.5 25.5 0.097 13.2 7.2 3.4 3 0 0 3 3 3 0 Spt5 transcription elongation factor, acidic N-terminal BTB PF00651.26 KLO19249.1 - 7e-07 29.2 0.8 1.6e-06 28.0 0.2 1.9 2 1 0 2 2 2 1 BTB/POZ domain Zn_clus PF00172.13 KLO19251.1 - 0.029 14.2 7.3 0.056 13.3 5.0 1.4 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain ProRS-C_1 PF09180.6 KLO19251.1 - 0.035 14.0 0.6 0.07 13.0 0.4 1.5 1 0 0 1 1 1 0 Prolyl-tRNA synthetase, C-terminal Zn_clus PF00172.13 KLO19252.1 - 0.23 11.4 9.9 0.42 10.5 6.8 1.5 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain HSP20 PF00011.16 KLO19254.1 - 7.5e-16 57.8 0.1 5.6e-09 35.7 0.0 2.2 2 0 0 2 2 2 2 Hsp20/alpha crystallin family Zn_clus PF00172.13 KLO19255.1 - 0.0042 16.9 13.9 0.0077 16.1 9.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-B_box PF00643.19 KLO19256.1 - 0.083 12.7 0.9 0.083 12.7 0.6 1.9 2 1 0 2 2 2 0 B-box zinc finger Zn_clus PF00172.13 KLO19256.1 - 0.78 9.7 14.5 0.17 11.8 6.6 2.0 1 1 1 2 2 2 0 Fungal Zn(2)-Cys(6) binuclear cluster domain PAP_assoc PF03828.14 KLO19261.1 - 1.3e-18 66.6 0.6 5e-18 64.7 0.1 2.2 2 0 0 2 2 2 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.18 KLO19261.1 - 5.8e-08 32.9 0.0 1.3e-07 31.8 0.0 1.6 1 0 0 1 1 1 1 Nucleotidyltransferase domain DNA_pol_B_palm PF14792.1 KLO19261.1 - 0.005 16.8 0.0 0.015 15.3 0.0 1.8 1 0 0 1 1 1 1 DNA polymerase beta palm TAP42 PF04177.7 KLO19262.1 - 2.8e-66 223.7 2.1 3.2e-66 223.6 1.4 1.0 1 0 0 1 1 1 1 TAP42-like family Ras PF00071.17 KLO19263.1 - 2.4e-56 189.6 0.2 3.2e-56 189.2 0.1 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KLO19263.1 - 1.2e-20 74.1 0.1 1.8e-20 73.5 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KLO19263.1 - 1.7e-14 53.4 0.2 2.1e-14 53.1 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 KLO19263.1 - 8e-07 28.4 0.2 1.3e-06 27.7 0.1 1.4 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.22 KLO19263.1 - 2.8e-06 26.8 0.3 1.6e-05 24.4 0.1 2.1 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 KLO19263.1 - 3.8e-06 26.8 0.1 1e-05 25.4 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 KLO19263.1 - 8.8e-06 25.0 0.2 1.1e-05 24.7 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region PduV-EutP PF10662.4 KLO19263.1 - 0.014 14.8 1.0 0.13 11.7 0.7 2.2 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation FeoB_N PF02421.13 KLO19263.1 - 0.032 13.5 0.3 1.2 8.3 0.2 2.2 1 1 0 1 1 1 0 Ferrous iron transport protein B MobB PF03205.9 KLO19263.1 - 0.04 13.6 0.4 1 9.0 0.0 2.3 2 1 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B Dynamin_N PF00350.18 KLO19263.1 - 0.047 13.5 0.2 1.8 8.3 0.0 2.7 2 1 1 3 3 3 0 Dynamin family MTHFR PF02219.12 KLO19264.1 - 2.6e-105 351.6 0.0 3.5e-105 351.2 0.0 1.1 1 0 0 1 1 1 1 Methylenetetrahydrofolate reductase WD40 PF00400.27 KLO19265.1 - 2.4e-19 68.3 16.3 3.9e-05 23.3 0.3 5.1 5 0 0 5 5 5 4 WD domain, G-beta repeat Transket_pyr PF02779.19 KLO19266.1 - 2.6e-39 134.5 0.1 3.7e-39 134.0 0.1 1.2 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.15 KLO19266.1 - 1.3e-28 99.4 0.0 1.6e-27 95.8 0.0 2.4 2 1 0 2 2 2 1 Transketolase, C-terminal domain POT1 PF02765.12 KLO19268.1 - 5.3e-07 29.6 0.0 1.2e-06 28.5 0.0 1.5 1 0 0 1 1 1 1 Telomeric single stranded DNA binding POT1/CDC13 Peptidase_S8 PF00082.17 KLO19269.1 - 3.4e-45 154.3 1.6 4.8e-45 153.8 1.1 1.2 1 0 0 1 1 1 1 Subtilase family P_proprotein PF01483.15 KLO19269.1 - 9.3e-29 99.0 0.4 1.8e-28 98.1 0.3 1.5 1 0 0 1 1 1 1 Proprotein convertase P-domain PepSY_TM_2 PF13703.1 KLO19269.1 - 0.16 12.1 0.4 0.37 10.9 0.3 1.5 1 0 0 1 1 1 0 PepSY-associated TM helix MCM PF00493.18 KLO19270.1 - 1.7e-137 457.7 0.2 1.6e-135 451.1 0.0 2.2 2 0 0 2 2 2 2 MCM2/3/5 family MCM_N PF14551.1 KLO19270.1 - 5.5e-29 101.1 2.3 4.1e-28 98.3 0.8 2.4 2 0 0 2 2 2 1 MCM N-terminal domain AAA_5 PF07728.9 KLO19270.1 - 9.2e-08 31.9 0.4 9.2e-07 28.6 0.0 2.9 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.16 KLO19270.1 - 9.5e-08 31.4 0.1 1.6e-05 24.2 0.0 2.4 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI Mg_chelatase_2 PF13335.1 KLO19270.1 - 0.00063 20.0 2.3 0.00066 20.0 0.0 2.3 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.6 KLO19270.1 - 0.006 16.1 0.1 0.023 14.2 0.0 2.0 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA PF00004.24 KLO19270.1 - 0.047 13.8 1.2 0.8 9.9 0.0 2.8 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 KLO19270.1 - 0.069 12.6 0.1 0.65 9.4 0.0 2.3 2 0 0 2 2 2 0 Sigma-54 interaction domain DNA_methylase PF00145.12 KLO19271.1 - 3.4e-52 177.6 0.0 1.2e-51 175.7 0.0 1.9 1 1 0 1 1 1 1 C-5 cytosine-specific DNA methylase BAH PF01426.13 KLO19271.1 - 8.9e-19 67.3 0.0 6.4e-14 51.7 0.0 3.0 3 0 0 3 3 3 2 BAH domain DNMT1-RFD PF12047.3 KLO19271.1 - 4.5e-13 49.1 0.1 8.5e-13 48.2 0.0 1.5 1 0 0 1 1 1 1 Cytosine specific DNA methyltransferase replication foci domain HMGL-like PF00682.14 KLO19272.1 - 4.2e-62 209.8 0.0 6.5e-62 209.2 0.0 1.3 1 0 0 1 1 1 1 HMGL-like LeuA_dimer PF08502.5 KLO19272.1 - 5.5e-45 152.4 0.1 5.5e-23 81.2 0.0 2.7 2 0 0 2 2 2 2 LeuA allosteric (dimerisation) domain DUF77 PF01910.12 KLO19273.1 - 7.9e-29 99.1 0.0 9.5e-29 98.9 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function DUF77 Ykof PF07615.6 KLO19273.1 - 0.00023 21.2 0.0 0.00033 20.7 0.0 1.2 1 0 0 1 1 1 1 YKOF-related Family DUF2102 PF09875.4 KLO19273.1 - 0.064 12.7 0.0 0.092 12.2 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2102) VRR_NUC PF08774.6 KLO19274.1 - 1.3e-19 70.0 0.0 3.1e-19 68.8 0.0 1.7 1 0 0 1 1 1 1 VRR-NUC domain Dehydrin PF00257.14 KLO19275.1 - 0.32 11.3 0.1 0.32 11.3 0.1 3.2 3 1 0 3 3 3 0 Dehydrin PMM PF03332.8 KLO19276.1 - 1.3e-107 358.3 1.3 1.6e-107 358.1 0.9 1.0 1 0 0 1 1 1 1 Eukaryotic phosphomannomutase Hydrolase_3 PF08282.7 KLO19276.1 - 0.014 15.0 0.0 0.12 11.9 0.0 2.0 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase HAS-barrel PF09378.5 KLO19276.1 - 0.035 14.0 0.3 1.9 8.4 0.1 2.4 1 1 1 2 2 2 0 HAS barrel domain S6PP PF05116.8 KLO19276.1 - 0.035 13.4 0.0 0.25 10.5 0.0 1.9 2 0 0 2 2 2 0 Sucrose-6F-phosphate phosphohydrolase TMPIT PF07851.8 KLO19276.1 - 0.085 11.9 0.0 0.12 11.3 0.0 1.2 1 0 0 1 1 1 0 TMPIT-like protein zf-H2C2_5 PF13909.1 KLO19277.1 - 0.16 12.2 2.9 1.3 9.4 0.1 2.9 2 0 0 2 2 2 0 C2H2-type zinc-finger domain zf-C2H2 PF00096.21 KLO19277.1 - 0.2 12.0 14.2 0.58 10.6 0.4 4.1 4 0 0 4 4 4 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KLO19277.1 - 0.48 10.8 14.6 0.33 11.3 0.5 3.7 3 0 0 3 3 3 0 C2H2-type zinc finger NUDIX PF00293.23 KLO19278.1 - 2e-12 46.8 0.0 6.7e-12 45.2 0.0 1.8 1 1 0 1 1 1 1 NUDIX domain Vma12 PF11712.3 KLO19279.1 - 7.5e-10 38.6 0.0 2.2e-09 37.1 0.0 1.7 2 0 0 2 2 2 1 Endoplasmic reticulum-based factor for assembly of V-ATPase DUF1469 PF07332.6 KLO19279.1 - 0.068 12.9 0.2 0.14 11.8 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1469) DUF3556 PF12077.3 KLO19279.1 - 0.11 10.4 0.0 0.14 10.1 0.0 1.1 1 0 0 1 1 1 0 Transmembrane protein of unknown function (DUF3556) Atx10homo_assoc PF09759.4 KLO19280.1 - 1.1e-25 89.3 0.5 1.8e-23 82.1 0.0 2.9 3 0 0 3 3 3 2 Spinocerebellar ataxia type 10 protein domain Leo1 PF04004.8 KLO19281.1 - 1.8e-47 161.2 0.1 1.8e-47 161.2 0.1 2.5 3 0 0 3 3 3 1 Leo1-like protein Cnd2 PF05786.9 KLO19285.1 - 8.9e-158 527.0 8.7 8.9e-158 527.0 6.1 1.5 1 1 0 1 1 1 1 Condensin complex subunit 2 Prenyltrans PF00432.16 KLO19286.1 - 5.6e-32 108.9 8.5 5.4e-09 35.4 0.0 6.4 7 0 0 7 7 7 5 Prenyltransferase and squalene oxidase repeat Prenyltrans_1 PF13243.1 KLO19286.1 - 5.3e-30 103.6 0.7 2.2e-12 46.9 0.0 6.2 3 3 3 6 6 6 5 Prenyltransferase-like Prenyltrans_2 PF13249.1 KLO19286.1 - 1.2e-28 99.7 1.4 3.5e-14 53.1 0.0 5.2 4 1 1 5 5 5 4 Prenyltransferase-like Pec_lyase PF09492.5 KLO19286.1 - 1e-07 31.4 0.1 0.17 11.0 0.0 5.1 3 1 2 5 5 5 2 Pectic acid lyase A2M_comp PF07678.9 KLO19286.1 - 5.4e-07 29.0 0.4 0.012 14.8 0.1 4.2 2 1 2 4 4 4 2 A-macroglobulin complement component AAA PF00004.24 KLO19287.1 - 9.1e-98 323.5 0.0 7.3e-48 162.1 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) CDC48_N PF02359.13 KLO19287.1 - 7.9e-21 73.8 0.8 2.7e-20 72.1 0.4 2.0 2 0 0 2 2 1 1 Cell division protein 48 (CDC48), N-terminal domain RuvB_N PF05496.7 KLO19287.1 - 2.9e-15 55.9 0.1 1.5e-05 24.1 0.0 4.0 4 0 0 4 4 4 2 Holliday junction DNA helicase ruvB N-terminus AAA_2 PF07724.9 KLO19287.1 - 6.1e-14 52.2 0.0 1.4e-07 31.6 0.0 2.7 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_33 PF13671.1 KLO19287.1 - 3.2e-13 49.7 0.0 1.2e-06 28.4 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_5 PF07728.9 KLO19287.1 - 2e-12 47.0 0.3 8.4e-06 25.5 0.1 4.0 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 KLO19287.1 - 1.8e-11 44.2 0.3 0.0022 18.1 0.0 4.6 3 2 0 3 3 3 2 AAA domain AAA_17 PF13207.1 KLO19287.1 - 2.3e-11 44.5 0.0 0.00056 20.7 0.0 3.0 2 1 0 2 2 2 2 AAA domain CDC48_2 PF02933.12 KLO19287.1 - 5.6e-11 41.9 0.0 1.1e-10 40.9 0.0 1.5 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), domain 2 AAA_16 PF13191.1 KLO19287.1 - 8.6e-10 38.8 0.0 0.001 19.0 0.0 3.1 2 2 0 2 2 2 2 AAA ATPase domain TIP49 PF06068.8 KLO19287.1 - 2.4e-09 36.4 0.6 0.0011 17.7 0.0 3.0 3 0 0 3 3 3 2 TIP49 C-terminus IstB_IS21 PF01695.12 KLO19287.1 - 2.9e-08 33.3 0.0 0.0038 16.6 0.0 2.7 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_14 PF13173.1 KLO19287.1 - 5.4e-08 32.7 0.0 0.0057 16.5 0.0 3.2 3 0 0 3 3 3 2 AAA domain Zeta_toxin PF06414.7 KLO19287.1 - 5.8e-08 32.0 0.0 0.0093 15.0 0.0 2.5 2 0 0 2 2 2 2 Zeta toxin AAA_25 PF13481.1 KLO19287.1 - 6.8e-08 32.1 2.7 0.016 14.6 0.0 3.9 2 2 1 4 4 4 2 AAA domain AAA_19 PF13245.1 KLO19287.1 - 2.1e-07 30.5 0.9 0.0089 15.7 0.0 2.9 2 0 0 2 2 2 2 Part of AAA domain Mg_chelatase PF01078.16 KLO19287.1 - 3.4e-07 29.6 0.3 0.023 13.8 0.0 2.5 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI KaiC PF06745.8 KLO19287.1 - 6e-07 28.8 0.5 0.16 11.0 0.0 3.4 2 1 1 3 3 3 2 KaiC RNA_helicase PF00910.17 KLO19287.1 - 1.1e-06 28.7 0.0 0.016 15.3 0.0 2.8 2 0 0 2 2 2 2 RNA helicase AAA_18 PF13238.1 KLO19287.1 - 1.5e-06 28.5 0.0 0.034 14.4 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_28 PF13521.1 KLO19287.1 - 7.1e-06 26.0 0.0 0.11 12.5 0.0 2.6 2 0 0 2 2 2 2 AAA domain ResIII PF04851.10 KLO19287.1 - 7.2e-06 25.9 0.0 0.0046 16.7 0.0 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Parvo_NS1 PF01057.12 KLO19287.1 - 8.7e-06 24.7 0.1 0.0083 15.0 0.0 2.2 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 ABC_tran PF00005.22 KLO19287.1 - 1.1e-05 25.7 0.0 0.12 12.7 0.0 3.8 3 1 0 3 3 2 1 ABC transporter Sigma54_activat PF00158.21 KLO19287.1 - 1.8e-05 24.2 0.0 0.38 10.1 0.0 3.2 2 1 0 2 2 2 2 Sigma-54 interaction domain AAA_24 PF13479.1 KLO19287.1 - 2.6e-05 23.9 0.0 0.11 12.1 0.0 3.1 3 0 0 3 3 2 2 AAA domain PhoH PF02562.11 KLO19287.1 - 4.1e-05 22.8 0.2 0.23 10.6 0.0 2.5 2 0 0 2 2 2 2 PhoH-like protein Sigma54_activ_2 PF14532.1 KLO19287.1 - 6.1e-05 23.0 0.0 0.47 10.4 0.0 2.8 3 0 0 3 3 2 2 Sigma-54 interaction domain DUF815 PF05673.8 KLO19287.1 - 0.00011 21.2 0.0 0.03 13.2 0.0 2.6 2 0 0 2 2 2 1 Protein of unknown function (DUF815) Bac_DnaA PF00308.13 KLO19287.1 - 0.00012 21.7 0.0 0.66 9.5 0.0 2.6 2 0 0 2 2 2 2 Bacterial dnaA protein Vps4_C PF09336.5 KLO19287.1 - 0.00019 21.2 0.0 0.0012 18.6 0.0 2.4 2 0 0 2 2 1 1 Vps4 C terminal oligomerisation domain AAA_3 PF07726.6 KLO19287.1 - 0.00022 20.8 0.0 0.59 9.7 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) Arch_ATPase PF01637.13 KLO19287.1 - 0.00024 20.8 0.0 2.7 7.6 0.0 3.3 2 1 1 3 3 3 1 Archaeal ATPase AAA_11 PF13086.1 KLO19287.1 - 0.0003 20.4 0.0 0.75 9.3 0.0 2.8 3 0 0 3 3 2 2 AAA domain Viral_helicase1 PF01443.13 KLO19287.1 - 0.00033 20.2 0.0 0.23 10.9 0.0 3.1 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase NACHT PF05729.7 KLO19287.1 - 0.00048 19.8 0.1 0.5 10.0 0.0 3.5 4 0 0 4 4 4 1 NACHT domain DUF2075 PF09848.4 KLO19287.1 - 0.00073 18.6 0.0 0.36 9.7 0.0 2.3 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) AAA_30 PF13604.1 KLO19287.1 - 0.00075 19.1 0.0 1.1 8.8 0.0 2.8 3 0 0 3 3 2 1 AAA domain NB-ARC PF00931.17 KLO19287.1 - 0.0033 16.3 0.0 0.25 10.1 0.0 2.3 2 0 0 2 2 2 1 NB-ARC domain NTPase_1 PF03266.10 KLO19287.1 - 0.0034 17.0 0.3 1.2 8.8 0.0 3.4 3 0 0 3 3 3 1 NTPase T2SE PF00437.15 KLO19287.1 - 0.0036 16.2 0.0 0.26 10.1 0.0 2.4 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_10 PF12846.2 KLO19287.1 - 0.023 14.1 1.1 5.1 6.4 0.0 3.8 3 1 0 4 4 4 0 AAA-like domain IPT PF01745.11 KLO19287.1 - 0.037 13.1 0.0 1.9 7.5 0.0 2.2 2 0 0 2 2 2 0 Isopentenyl transferase UPF0079 PF02367.12 KLO19287.1 - 0.044 13.4 0.1 3.5 7.2 0.0 2.5 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 KTI12 PF08433.5 KLO19287.1 - 0.053 12.7 0.0 7.4 5.6 0.0 2.6 2 0 0 2 2 2 0 Chromatin associated protein KTI12 SKI PF01202.17 KLO19287.1 - 0.09 12.6 0.0 7.5 6.3 0.0 2.5 2 0 0 2 2 2 0 Shikimate kinase ATP-synt_ab PF00006.20 KLO19287.1 - 0.098 12.1 0.0 8.4 5.8 0.0 2.3 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain UFD1 PF03152.9 KLO19287.1 - 0.13 11.3 0.0 0.39 9.8 0.0 1.6 1 1 0 1 1 1 0 Ubiquitin fusion degradation protein UFD1 KAP_NTPase PF07693.9 KLO19287.1 - 0.15 10.9 0.0 2 7.3 0.0 2.3 2 1 0 2 2 2 0 KAP family P-loop domain Amidase PF01425.16 KLO19288.1 - 1.1e-102 344.1 3.5 2.5e-102 342.9 2.4 1.5 1 1 0 1 1 1 1 Amidase BRAP2 PF07576.7 KLO19289.1 - 8.8e-25 86.4 0.0 1.7e-24 85.5 0.0 1.4 1 0 0 1 1 1 1 BRCA1-associated protein 2 zf-UBP PF02148.14 KLO19289.1 - 2.9e-20 72.1 2.8 1.4e-19 69.9 2.3 1.8 2 0 0 2 2 2 1 Zn-finger in ubiquitin-hydrolases and other protein zf-RING_2 PF13639.1 KLO19289.1 - 2e-09 37.1 10.2 2e-09 37.1 7.0 1.7 2 0 0 2 2 1 1 Ring finger domain zf-rbx1 PF12678.2 KLO19289.1 - 1.4e-05 25.1 2.2 3.8e-05 23.7 1.5 1.8 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 KLO19289.1 - 4.2e-05 23.1 7.1 0.00011 21.8 4.9 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 KLO19289.1 - 9.5e-05 21.9 6.5 9.5e-05 21.9 4.5 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KLO19289.1 - 0.00012 22.0 9.0 0.00012 22.0 6.3 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KLO19289.1 - 0.0002 21.0 6.9 0.0002 21.0 4.8 2.1 2 0 0 2 2 2 1 zinc-RING finger domain zf-Apc11 PF12861.2 KLO19289.1 - 0.0052 16.5 3.6 0.013 15.3 2.5 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Exonuc_VII_L PF02601.10 KLO19289.1 - 0.038 13.1 8.2 0.06 12.5 5.7 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit zf-RING_4 PF14570.1 KLO19289.1 - 0.046 13.3 6.0 0.12 12.0 4.1 1.7 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING_UBOX PF13445.1 KLO19289.1 - 0.058 13.1 2.8 0.13 11.9 0.9 2.4 1 1 1 2 2 2 0 RING-type zinc-finger Homoserine_dh PF00742.14 KLO19289.1 - 0.06 13.0 4.8 0.11 12.1 3.3 1.3 1 0 0 1 1 1 0 Homoserine dehydrogenase RRM_1 PF00076.17 KLO19289.1 - 0.096 12.3 0.0 0.21 11.2 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) AAA_13 PF13166.1 KLO19289.1 - 0.12 10.7 18.6 0.18 10.2 12.9 1.1 1 0 0 1 1 1 0 AAA domain zf-C3HC4_4 PF15227.1 KLO19289.1 - 0.28 11.1 6.2 1.2 9.1 4.3 2.2 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING FlaC_arch PF05377.6 KLO19289.1 - 0.5 10.2 5.8 0.4 10.6 0.9 2.6 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) Lipoprotein_20 PF13942.1 KLO19289.1 - 0.74 9.3 18.6 0.21 11.1 2.4 2.6 1 1 1 2 2 2 0 YfhG lipoprotein TerY-C PF15616.1 KLO19289.1 - 1.5 8.7 14.0 1.3 8.9 3.3 2.8 1 1 1 2 2 2 0 TerY-C metal binding domain DUF2968 PF11180.3 KLO19289.1 - 7.3 5.9 16.8 3.5 6.9 3.9 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2968) Actin PF00022.14 KLO19290.1 - 3.1e-34 118.0 0.0 4.7e-34 117.4 0.0 1.2 1 0 0 1 1 1 1 Actin MreB_Mbl PF06723.8 KLO19290.1 - 6.5e-06 24.9 0.0 1.3e-05 23.9 0.0 1.5 1 0 0 1 1 1 1 MreB/Mbl protein WD40 PF00400.27 KLO19291.1 - 4.5e-28 96.0 9.5 5e-08 32.5 0.0 5.7 5 1 0 5 5 5 5 WD domain, G-beta repeat BBS2_Mid PF14783.1 KLO19291.1 - 0.0019 17.9 0.0 2.6 7.8 0.0 2.7 3 0 0 3 3 3 2 Ciliary BBSome complex subunit 2, middle region Nup160 PF11715.3 KLO19291.1 - 0.07 11.2 0.3 4.9 5.1 0.0 2.7 1 1 0 2 2 2 0 Nucleoporin Nup120/160 DUF1604 PF07713.8 KLO19292.1 - 7e-38 128.3 2.5 1.9e-37 126.8 1.0 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF1604) G-patch PF01585.18 KLO19292.1 - 0.00023 20.9 0.1 0.00023 20.9 0.0 2.4 2 0 0 2 2 2 1 G-patch domain AA_permease PF00324.16 KLO19293.1 - 5.4e-118 394.3 33.4 6.2e-118 394.1 23.1 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 KLO19293.1 - 7e-35 120.3 38.6 8.6e-35 120.0 26.7 1.1 1 0 0 1 1 1 1 Amino acid permease Methyltransf_12 PF08242.7 KLO19294.1 - 6.1e-12 45.8 0.0 1.7e-11 44.4 0.0 1.8 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KLO19294.1 - 4.3e-10 39.5 0.0 7.4e-10 38.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KLO19294.1 - 2.1e-08 34.4 0.0 3.5e-08 33.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KLO19294.1 - 2.6e-08 34.2 0.0 6.8e-08 32.9 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KLO19294.1 - 7.5e-07 29.7 0.0 1.3e-06 28.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KLO19294.1 - 1.7e-06 27.6 0.0 2.9e-06 26.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 KLO19294.1 - 0.00026 20.9 0.0 0.00053 20.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain TehB PF03848.9 KLO19294.1 - 0.0018 17.4 0.0 0.0025 17.0 0.0 1.2 1 0 0 1 1 1 1 Tellurite resistance protein TehB NNMT_PNMT_TEMT PF01234.12 KLO19294.1 - 0.0043 16.0 0.0 0.079 11.9 0.0 2.0 2 0 0 2 2 2 1 NNMT/PNMT/TEMT family MTS PF05175.9 KLO19294.1 - 0.0048 16.2 0.0 0.0081 15.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Ubie_methyltran PF01209.13 KLO19294.1 - 0.0064 15.6 0.0 0.0097 15.0 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family RhoGEF PF00621.15 KLO19295.1 - 2.9e-67 226.0 0.7 1.6e-33 116.1 0.0 2.3 2 0 0 2 2 2 2 RhoGEF domain CNH PF00780.17 KLO19295.1 - 1.2e-61 208.6 0.0 2.3e-61 207.6 0.0 1.5 1 0 0 1 1 1 1 CNH domain PH_5 PF15405.1 KLO19295.1 - 4.3e-17 62.3 0.0 9.9e-17 61.1 0.0 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain PH PF00169.24 KLO19295.1 - 5.1e-07 29.8 0.0 6.4e-06 26.3 0.0 2.5 2 0 0 2 2 2 1 PH domain DEP PF00610.16 KLO19295.1 - 0.00026 20.6 0.0 0.0006 19.5 0.0 1.6 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) Bud13 PF09736.4 KLO19296.1 - 2.2e-47 160.9 6.8 2.2e-47 160.9 4.7 2.2 4 0 0 4 4 4 1 Pre-mRNA-splicing factor of RES complex Sin_N PF04801.8 KLO19296.1 - 0.27 10.0 3.2 0.38 9.5 2.2 1.1 1 0 0 1 1 1 0 Sin-like protein conserved region DUF2312 PF10073.4 KLO19296.1 - 1.9 7.9 10.0 3.1 7.1 4.3 2.6 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2312) Pkinase_Tyr PF07714.12 KLO19297.1 - 2.8e-09 36.4 0.0 6.9e-09 35.1 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 KLO19297.1 - 2.2e-08 33.5 0.0 7.9e-08 31.7 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain WD40 PF00400.27 KLO19298.1 - 2e-57 189.1 25.9 8.2e-09 35.0 0.0 7.5 7 0 0 7 7 7 7 WD domain, G-beta repeat Pkinase PF00069.20 KLO19298.1 - 6.5e-45 153.2 0.0 9.6e-45 152.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KLO19298.1 - 5.9e-44 150.0 0.0 9.2e-44 149.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KLO19298.1 - 4.3e-05 22.6 0.0 8e-05 21.7 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Nucleoporin_N PF08801.6 KLO19298.1 - 0.0013 17.5 0.0 0.081 11.6 0.0 3.1 1 1 2 3 3 3 1 Nup133 N terminal like Nup160 PF11715.3 KLO19298.1 - 0.011 13.9 0.5 0.11 10.6 0.2 2.5 1 1 0 1 1 1 0 Nucleoporin Nup120/160 PD40 PF07676.7 KLO19298.1 - 0.013 15.1 0.1 23 4.7 0.0 4.1 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat RIO1 PF01163.17 KLO19298.1 - 0.042 13.2 0.0 0.091 12.0 0.0 1.5 1 0 0 1 1 1 0 RIO1 family WD40 PF00400.27 KLO19299.1 - 1.5e-66 218.0 20.4 1.3e-11 43.8 0.1 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat Nucleoporin_N PF08801.6 KLO19299.1 - 3.8e-07 29.1 0.4 0.015 14.0 0.0 3.4 1 1 2 3 3 3 2 Nup133 N terminal like Cytochrom_D1 PF02239.11 KLO19299.1 - 5.4e-06 24.9 0.5 0.0012 17.1 0.0 2.6 1 1 2 3 3 3 2 Cytochrome D1 heme domain Nup160 PF11715.3 KLO19299.1 - 7.3e-06 24.4 0.6 0.056 11.5 0.1 4.0 1 1 2 3 3 3 3 Nucleoporin Nup120/160 PD40 PF07676.7 KLO19299.1 - 9.1e-06 25.2 0.2 14 5.4 0.0 5.7 6 0 0 6 6 6 0 WD40-like Beta Propeller Repeat PQQ_2 PF13360.1 KLO19299.1 - 0.00024 20.6 1.1 0.004 16.6 0.6 2.5 1 1 0 1 1 1 1 PQQ-like domain Nbas_N PF15492.1 KLO19299.1 - 0.0003 20.0 0.6 5.5 6.0 0.0 4.4 1 1 3 5 5 5 2 Neuroblastoma-amplified sequence, N terminal Gmad1 PF10647.4 KLO19299.1 - 0.0016 17.9 0.0 0.013 14.9 0.0 2.1 1 1 1 2 2 2 2 Lipoprotein LpqB beta-propeller domain PSII_BNR PF14870.1 KLO19299.1 - 0.019 13.9 0.0 0.032 13.2 0.0 1.4 1 0 0 1 1 1 0 Photosynthesis system II assembly factor YCF48 Reg_prop PF07494.6 KLO19299.1 - 0.025 14.5 0.5 7.8 6.9 0.0 4.4 4 0 0 4 4 4 0 Two component regulator propeller Proteasome_A_N PF10584.4 KLO19299.1 - 0.084 12.2 2.1 20 4.6 0.0 3.9 5 0 0 5 5 5 0 Proteasome subunit A N-terminal signature FliS PF02561.9 KLO19302.1 - 0.016 15.0 0.0 0.04 13.7 0.0 1.6 1 0 0 1 1 1 0 Flagellar protein FliS DUF4131 PF13567.1 KLO19302.1 - 0.084 12.2 0.1 0.17 11.2 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) NUDIX PF00293.23 KLO19303.1 - 2e-14 53.3 0.6 4.4e-13 49.0 0.0 2.2 1 1 0 2 2 2 2 NUDIX domain Pox_A_type_inc PF04508.7 KLO19304.1 - 0.00066 19.2 17.0 0.091 12.5 0.1 5.9 5 1 1 6 6 6 2 Viral A-type inclusion protein repeat ADIP PF11559.3 KLO19304.1 - 0.43 10.4 29.6 0.59 10.0 2.6 4.0 3 1 1 4 4 4 0 Afadin- and alpha -actinin-Binding HALZ PF02183.13 KLO19304.1 - 1.3 8.7 19.6 5.9 6.6 0.1 5.3 5 0 0 5 5 5 0 Homeobox associated leucine zipper FlaC_arch PF05377.6 KLO19304.1 - 2.5 8.0 13.7 1.9 8.4 0.4 4.6 5 1 0 5 5 5 0 Flagella accessory protein C (FlaC) DUF972 PF06156.8 KLO19304.1 - 3.2 8.1 29.3 0.28 11.5 1.6 4.2 1 1 3 4 4 4 0 Protein of unknown function (DUF972) Ribosomal_L29 PF00831.18 KLO19304.1 - 3.6 7.3 10.1 0.32 10.6 0.1 3.9 3 1 1 4 4 4 0 Ribosomal L29 protein TSC22 PF01166.13 KLO19304.1 - 5.8 6.9 27.6 0.37 10.7 2.7 5.9 4 3 3 7 7 7 0 TSC-22/dip/bun family Baculo_PEP_C PF04513.7 KLO19304.1 - 7 6.4 9.5 8.2 6.2 0.5 3.1 2 2 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Wbp11 PF09429.5 KLO19304.1 - 7.4 6.6 21.0 7.7 6.5 2.8 3.9 3 1 0 3 3 3 0 WW domain binding protein 11 Rsc14 PF08586.5 KLO19304.1 - 8.2 6.9 13.2 1.1 9.7 1.5 2.9 3 1 0 3 3 3 0 RSC complex, Rsc14/Ldb7 subunit DASH_Hsk3 PF08227.6 KLO19304.1 - 9.2 6.5 7.8 3.9 7.7 0.0 3.4 4 0 0 4 4 3 0 DASH complex subunit Hsk3 like RmlD_sub_bind PF04321.12 KLO19305.1 - 4.2e-55 186.6 0.0 5e-55 186.4 0.0 1.0 1 0 0 1 1 1 1 RmlD substrate binding domain Epimerase PF01370.16 KLO19305.1 - 4.6e-25 88.4 0.0 1.2e-24 87.0 0.0 1.5 1 1 1 2 2 2 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 KLO19305.1 - 1.2e-09 38.4 0.0 1.6e-09 37.9 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding Polysacc_synt_2 PF02719.10 KLO19305.1 - 8.2e-06 24.9 0.1 0.00036 19.5 0.0 2.8 1 1 1 2 2 2 1 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.7 KLO19305.1 - 2.3e-05 23.4 0.0 0.00086 18.2 0.0 2.5 1 1 2 3 3 3 1 Male sterility protein NmrA PF05368.8 KLO19305.1 - 0.0045 16.2 0.0 0.018 14.2 0.0 1.8 2 0 0 2 2 2 1 NmrA-like family DapB_N PF01113.15 KLO19305.1 - 0.0094 15.8 0.0 0.018 14.9 0.0 1.5 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus adh_short PF00106.20 KLO19305.1 - 0.022 14.7 0.6 0.059 13.2 0.4 1.7 1 1 0 1 1 1 0 short chain dehydrogenase NfeD PF01957.13 KLO19307.1 - 0.059 13.5 0.2 0.059 13.5 0.1 2.8 2 1 2 4 4 4 0 NfeD-like C-terminal, partner-binding DUF155 PF02582.9 KLO19308.1 - 2.5e-47 161.0 0.0 4.9e-47 160.0 0.0 1.5 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 Cnl2_NKP2 PF09447.5 KLO19308.1 - 0.12 12.0 0.0 0.3 10.7 0.0 1.6 1 0 0 1 1 1 0 Cnl2/NKP2 family protein LSM PF01423.17 KLO19309.1 - 7.8e-15 54.1 0.1 9.5e-15 53.9 0.0 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 KLO19309.1 - 0.11 12.3 0.0 0.13 12.1 0.0 1.2 1 0 0 1 1 1 0 Ataxin 2 SM domain Glyco_tranf_2_3 PF13641.1 KLO19310.1 - 0.056 13.2 0.0 0.072 12.8 0.0 1.1 1 0 0 1 1 1 0 Glycosyltransferase like family 2 AHS2 PF02626.10 KLO19311.1 - 2.3e-64 217.2 0.0 3.8e-64 216.6 0.0 1.3 1 0 0 1 1 1 1 Allophanate hydrolase subunit 2 CPSase_L_D2 PF02786.12 KLO19311.1 - 3.2e-58 196.5 0.0 6.4e-58 195.5 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain AHS1 PF02682.11 KLO19311.1 - 4.6e-36 124.2 0.0 9.5e-36 123.1 0.0 1.5 1 0 0 1 1 1 1 Allophanate hydrolase subunit 1 CPSase_L_chain PF00289.17 KLO19311.1 - 8.7e-33 112.7 0.0 2.8e-32 111.1 0.0 1.9 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, N-terminal domain Biotin_carb_C PF02785.14 KLO19311.1 - 5.5e-26 90.6 0.0 2.2e-25 88.7 0.0 2.0 1 1 0 1 1 1 1 Biotin carboxylase C-terminal domain ATP-grasp_4 PF13535.1 KLO19311.1 - 8.3e-15 54.9 0.0 2.1e-14 53.7 0.0 1.6 1 0 0 1 1 1 1 ATP-grasp domain ATPgrasp_Ter PF15632.1 KLO19311.1 - 8.4e-12 44.4 0.0 3.8e-09 35.7 0.0 2.1 2 0 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon Dala_Dala_lig_C PF07478.8 KLO19311.1 - 5.5e-08 32.4 0.0 1e-07 31.5 0.0 1.4 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus Biotin_lipoyl PF00364.17 KLO19311.1 - 7.7e-08 31.8 2.7 2.7e-07 30.1 1.9 2.0 1 0 0 1 1 1 1 Biotin-requiring enzyme RimK PF08443.6 KLO19311.1 - 0.0027 17.2 0.0 0.012 15.0 0.0 1.9 2 0 0 2 2 2 1 RimK-like ATP-grasp domain ATP-grasp PF02222.17 KLO19311.1 - 0.061 12.6 0.0 0.1 11.9 0.0 1.3 1 0 0 1 1 1 0 ATP-grasp domain DASH_Dam1 PF08653.5 KLO19312.1 - 6.7e-14 51.3 0.1 1.2e-13 50.6 0.0 1.4 1 0 0 1 1 1 1 DASH complex subunit Dam1 DUF4519 PF15012.1 KLO19312.1 - 0.5 10.3 3.0 0.86 9.5 2.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4519) Aldo_ket_red PF00248.16 KLO19313.1 - 1.7e-76 256.7 0.0 2.1e-76 256.4 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family ELYS PF13934.1 KLO19314.1 - 2.1e-48 165.0 0.1 2.8e-48 164.6 0.0 1.2 1 0 0 1 1 1 1 Nuclear pore complex assembly Pkinase PF00069.20 KLO19316.1 - 1e-40 139.5 0.0 1.3e-40 139.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KLO19316.1 - 3.8e-20 72.0 0.0 5e-20 71.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 KLO19316.1 - 0.0016 17.5 0.0 0.0024 16.9 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KLO19316.1 - 0.026 14.2 0.4 0.063 13.0 0.3 1.5 1 1 0 1 1 1 0 Phosphotransferase enzyme family PhoPQ_related PF10142.4 KLO19318.1 - 0.13 10.7 0.0 0.18 10.2 0.0 1.3 1 0 0 1 1 1 0 PhoPQ-activated pathogenicity-related protein NDUFA12 PF05071.11 KLO19319.1 - 1.9e-05 25.0 1.4 3.1e-05 24.3 0.3 1.8 1 1 1 2 2 2 1 NADH ubiquinone oxidoreductase subunit NDUFA12 PPR PF01535.15 KLO19320.1 - 1.6e-06 27.6 0.0 0.00064 19.5 0.0 2.9 2 0 0 2 2 2 2 PPR repeat PPR_2 PF13041.1 KLO19320.1 - 0.00064 19.6 0.1 0.0019 18.1 0.1 1.8 1 0 0 1 1 1 1 PPR repeat family PPR_3 PF13812.1 KLO19320.1 - 0.00084 19.4 0.1 0.96 9.8 0.0 3.6 3 0 0 3 3 3 2 Pentatricopeptide repeat domain SWIRM PF04433.12 KLO19321.1 - 2.5e-35 120.4 0.0 6.2e-35 119.1 0.0 1.7 1 0 0 1 1 1 1 SWIRM domain ZZ PF00569.12 KLO19321.1 - 2.4e-09 36.5 2.4 4.1e-09 35.8 1.7 1.3 1 0 0 1 1 1 1 Zinc finger, ZZ type Myb_DNA-bind_6 PF13921.1 KLO19321.1 - 1.9e-08 34.2 0.0 3.8e-08 33.3 0.0 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 KLO19321.1 - 6.8e-08 32.4 0.0 1.2e-07 31.6 0.0 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain DUF2450 PF10475.4 KLO19321.1 - 0.055 12.3 1.7 0.096 11.5 1.2 1.3 1 0 0 1 1 1 0 Protein of unknown function N-terminal domain (DUF2450) MFS_1 PF07690.11 KLO19322.1 - 7.3e-28 97.2 26.7 7.7e-28 97.2 18.0 1.3 1 1 0 1 1 1 1 Major Facilitator Superfamily Use1 PF09753.4 KLO19322.1 - 0.09 12.2 2.5 0.19 11.1 1.7 1.5 1 0 0 1 1 1 0 Membrane fusion protein Use1 DUF2945 PF11160.3 KLO19323.1 - 2.4e-16 59.2 0.4 2.4e-16 59.2 0.3 2.4 3 0 0 3 3 3 1 Protein of unknown function (DUF2945) MIP-T3 PF10243.4 KLO19323.1 - 0.014 13.8 46.6 0.017 13.6 32.3 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Afi1 PF07792.7 KLO19324.1 - 2.5e-40 137.8 0.0 5.5e-40 136.7 0.0 1.6 1 1 0 1 1 1 1 Docking domain of Afi1 for Arf3 in vesicle trafficking SPA PF08616.5 KLO19324.1 - 3.5e-32 110.4 0.0 6.9e-32 109.5 0.0 1.5 1 0 0 1 1 1 1 Stabilization of polarity axis Avl9 PF09794.4 KLO19324.1 - 8.5e-05 21.2 0.0 0.011 14.2 0.0 3.0 2 1 0 3 3 3 1 Transport protein Avl9 Peptidase_C14 PF00656.17 KLO19325.1 - 6.5e-38 130.8 0.0 8.8e-38 130.3 0.0 1.1 1 0 0 1 1 1 1 Caspase domain RNA_pol_A_CTD PF03118.10 KLO19325.1 - 0.0017 17.7 0.1 0.0034 16.7 0.1 1.5 1 0 0 1 1 1 1 Bacterial RNA polymerase, alpha chain C terminal domain Peptidase_C14 PF00656.17 KLO19326.1 - 4.1e-33 115.1 0.1 6.5e-33 114.4 0.1 1.2 1 0 0 1 1 1 1 Caspase domain Sigma54_AID PF00309.15 KLO19327.1 - 0.11 11.9 0.2 0.17 11.3 0.1 1.2 1 0 0 1 1 1 0 Sigma-54 factor, Activator interacting domain (AID) Helicase_C PF00271.26 KLO19328.1 - 2.6e-16 59.2 0.0 1e-15 57.3 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.24 KLO19328.1 - 1.9e-13 50.2 0.0 1.3e-12 47.4 0.0 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase ResIII PF04851.10 KLO19328.1 - 0.0002 21.2 2.0 0.00084 19.2 0.0 2.8 3 1 0 3 3 3 1 Type III restriction enzyme, res subunit SNF2_N PF00176.18 KLO19328.1 - 0.0017 17.2 0.0 0.0098 14.7 0.0 2.0 1 1 1 2 2 2 1 SNF2 family N-terminal domain OmpH PF03938.9 KLO19328.1 - 0.38 10.6 18.9 0.8 9.6 13.1 1.5 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) DDHD PF02862.12 KLO19328.1 - 1.4 8.6 11.0 0.06 13.1 3.0 1.9 2 0 0 2 2 2 0 DDHD domain RIO1 PF01163.17 KLO19329.1 - 0.00015 21.1 0.0 0.00028 20.2 0.0 1.4 1 0 0 1 1 1 1 RIO1 family WaaY PF06176.6 KLO19329.1 - 0.00027 20.2 0.0 0.00059 19.1 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide core biosynthesis protein (WaaY) Pkinase PF00069.20 KLO19329.1 - 0.00063 18.9 0.0 0.001 18.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.18 KLO19329.1 - 0.0015 18.2 0.1 0.0026 17.5 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 KLO19329.1 - 0.0016 17.5 0.1 0.0037 16.3 0.0 1.5 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family F-box-like PF12937.2 KLO19330.1 - 1.2e-07 31.2 5.0 3.2e-07 29.9 1.0 2.4 2 0 0 2 2 2 2 F-box-like MAPEG PF01124.13 KLO19331.1 - 6.9e-16 58.0 0.6 7.7e-16 57.8 0.4 1.1 1 0 0 1 1 1 1 MAPEG family Cnd3 PF12719.2 KLO19332.1 - 3.9e-79 265.7 5.9 2.3e-78 263.2 3.5 2.2 2 0 0 2 2 2 1 Nuclear condensing complex subunits, C-term domain HEAT_2 PF13646.1 KLO19332.1 - 3.4e-06 27.2 5.7 0.0088 16.3 0.7 4.6 3 1 2 5 5 5 2 HEAT repeats HEAT PF02985.17 KLO19332.1 - 0.0029 17.5 2.8 0.67 10.1 0.0 4.8 5 0 0 5 5 5 1 HEAT repeat FMN_red PF03358.10 KLO19332.1 - 0.087 12.3 0.5 2.5 7.5 0.0 2.8 3 0 0 3 3 3 0 NADPH-dependent FMN reductase HEAT_EZ PF13513.1 KLO19332.1 - 0.49 10.9 4.2 41 4.8 0.1 4.4 3 1 1 4 4 4 0 HEAT-like repeat Cnd3 PF12719.2 KLO19333.1 - 5.7e-82 275.0 8.5 1.6e-80 270.3 2.1 2.9 2 1 0 2 2 2 2 Nuclear condensing complex subunits, C-term domain HEAT_2 PF13646.1 KLO19333.1 - 2.2e-14 53.5 5.0 5.1e-08 33.0 0.1 4.6 4 1 1 5 5 5 3 HEAT repeats HEAT PF02985.17 KLO19333.1 - 4.7e-10 38.6 5.5 0.038 14.0 0.0 6.0 5 0 0 5 5 5 3 HEAT repeat Adaptin_N PF01602.15 KLO19333.1 - 5.1e-06 25.0 1.3 5.3e-05 21.7 0.1 2.7 3 0 0 3 3 3 1 Adaptin N terminal region Vac14_Fab1_bd PF12755.2 KLO19333.1 - 0.0028 18.0 4.9 0.49 10.8 0.1 5.0 5 1 1 6 6 6 1 Vacuolar 14 Fab1-binding region TnpV PF14198.1 KLO19333.1 - 0.021 14.7 0.2 1.9 8.3 0.1 3.1 2 1 0 2 2 2 0 Transposon-encoded protein TnpV HEAT_EZ PF13513.1 KLO19333.1 - 0.12 12.8 8.9 2.4 8.7 1.2 4.8 3 1 2 5 5 5 0 HEAT-like repeat Cohesin_HEAT PF12765.2 KLO19333.1 - 0.33 10.9 11.6 0.41 10.6 0.2 4.3 4 0 0 4 4 4 0 HEAT repeat associated with sister chromatid cohesion SPT6_acidic PF14632.1 KLO19333.1 - 0.73 10.0 11.5 0.039 14.1 3.4 2.4 2 0 0 2 2 2 0 Acidic N-terminal SPT6 Pkinase PF00069.20 KLO19334.1 - 2e-73 246.7 0.0 2.9e-73 246.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KLO19334.1 - 3.2e-45 154.2 0.0 5e-45 153.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase POLO_box PF00659.13 KLO19334.1 - 1.6e-34 117.6 0.2 4.2e-19 68.2 0.0 2.9 2 0 0 2 2 2 2 POLO box duplicated region Kinase-like PF14531.1 KLO19334.1 - 9.6e-11 41.1 0.1 4.5e-10 38.9 0.0 2.1 3 0 0 3 3 3 1 Kinase-like DUF4520 PF15016.1 KLO19334.1 - 0.055 13.0 0.0 0.14 11.7 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4520) Kdo PF06293.9 KLO19334.1 - 0.068 12.2 0.0 0.18 10.8 0.0 1.7 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family zf-RING_2 PF13639.1 KLO19335.1 - 3.8e-12 45.8 12.5 7.7e-12 44.8 8.7 1.6 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 KLO19335.1 - 4.6e-08 33.0 5.7 1.2e-07 31.6 3.9 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_3 PF13920.1 KLO19335.1 - 1.5e-07 30.9 9.5 2.5e-07 30.2 6.6 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KLO19335.1 - 6.8e-06 25.6 11.4 1.3e-05 24.7 7.9 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KLO19335.1 - 6.9e-06 25.9 12.3 1.2e-05 25.1 8.5 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KLO19335.1 - 2.7e-05 23.7 10.6 4.7e-05 23.0 7.4 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-Apc11 PF12861.2 KLO19335.1 - 0.2 11.4 7.5 0.54 10.1 5.2 1.7 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.1 KLO19335.1 - 3.9 7.2 8.9 2.3 8.0 4.3 2.1 2 0 0 2 2 2 0 RING-type zinc-finger Arf PF00025.16 KLO19336.1 - 2.3e-43 147.4 0.0 2.9e-43 147.1 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.17 KLO19336.1 - 1.5e-18 66.6 0.0 2e-18 66.3 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KLO19336.1 - 1e-12 48.6 0.0 1.6e-12 48.0 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein SRPRB PF09439.5 KLO19336.1 - 1.5e-08 34.0 0.0 1.8e-08 33.8 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.7 KLO19336.1 - 1.6e-07 30.7 0.0 2e-07 30.3 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region G-alpha PF00503.15 KLO19336.1 - 6.9e-06 25.0 1.7 2.1e-05 23.3 0.3 2.3 2 1 0 2 2 2 1 G-protein alpha subunit GTP_EFTU PF00009.22 KLO19336.1 - 4e-05 23.1 0.0 9.8e-05 21.8 0.0 1.5 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 KLO19336.1 - 0.00012 21.9 0.0 0.00018 21.4 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.18 KLO19336.1 - 0.0036 17.1 0.4 0.45 10.3 0.4 2.3 1 1 1 2 2 2 1 Dynamin family ATP_bind_1 PF03029.12 KLO19336.1 - 0.037 13.5 0.2 4.2 6.8 0.0 2.1 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein CBS PF00571.23 KLO19339.1 - 2e-14 53.1 0.3 0.00014 21.6 0.0 4.3 4 0 0 4 4 4 3 CBS domain Gp58 PF07902.6 KLO19339.1 - 0.11 10.6 0.8 0.16 10.1 0.6 1.1 1 0 0 1 1 1 0 gp58-like protein Vps39_2 PF10367.4 KLO19340.1 - 1.7e-10 41.0 0.0 4.1e-10 39.8 0.0 1.6 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 2 Vps39_1 PF10366.4 KLO19340.1 - 7.6e-07 29.1 0.1 3.3e-06 27.0 0.0 2.1 2 0 0 2 2 2 1 Vacuolar sorting protein 39 domain 1 CNH PF00780.17 KLO19340.1 - 1.5e-06 27.8 0.0 1.4e-05 24.6 0.0 2.1 1 1 0 1 1 1 1 CNH domain Clathrin PF00637.15 KLO19340.1 - 0.0015 18.1 0.0 0.086 12.4 0.0 3.0 3 0 0 3 3 3 1 Region in Clathrin and VPS TPR_7 PF13176.1 KLO19340.1 - 0.2 11.5 1.2 33 4.6 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat Perilipin PF03036.11 KLO19341.1 - 4.9e-11 42.1 10.5 6.7e-11 41.6 0.1 3.2 1 1 1 3 3 3 1 Perilipin family Apolipoprotein PF01442.13 KLO19341.1 - 0.012 15.1 2.5 0.026 14.0 1.4 1.8 1 1 1 2 2 2 0 Apolipoprotein A1/A4/E domain DUF2551 PF10826.3 KLO19341.1 - 0.12 12.2 0.0 1.1 9.1 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2551) Baculo_PEP_C PF04513.7 KLO19341.1 - 0.14 11.9 3.7 4.3 7.1 1.3 2.7 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF883 PF05957.8 KLO19341.1 - 0.4 11.0 3.9 5.4 7.4 0.0 3.3 3 1 0 3 3 3 0 Bacterial protein of unknown function (DUF883) WD40 PF00400.27 KLO19343.1 - 1.4e-26 91.3 4.6 3.2e-06 26.7 0.0 6.4 7 0 0 7 7 7 5 WD domain, G-beta repeat eIF2A PF08662.6 KLO19343.1 - 0.017 14.8 0.1 0.16 11.6 0.0 2.2 2 0 0 2 2 2 0 Eukaryotic translation initiation factor eIF2A vATP-synt_E PF01991.13 KLO19343.1 - 0.11 11.7 0.0 0.17 11.1 0.0 1.1 1 0 0 1 1 1 0 ATP synthase (E/31 kDa) subunit CNH PF00780.17 KLO19343.1 - 0.16 11.3 0.0 1.2 8.5 0.0 2.0 1 1 0 1 1 1 0 CNH domain Cnd1 PF12717.2 KLO19344.1 - 1e-63 214.3 10.8 3e-59 199.8 0.9 4.0 3 1 1 4 4 4 2 non-SMC mitotic condensation complex subunit 1 Cnd1_N PF12922.2 KLO19344.1 - 3.8e-51 173.1 0.0 3.8e-51 173.1 0.0 4.7 5 0 0 5 5 5 1 non-SMC mitotic condensation complex subunit 1, N-term HEAT_2 PF13646.1 KLO19344.1 - 3.8e-09 36.7 4.0 0.004 17.3 0.0 5.3 6 1 1 7 7 7 3 HEAT repeats HEAT PF02985.17 KLO19344.1 - 0.0002 21.1 0.8 31 5.0 0.0 5.9 5 0 0 5 5 5 0 HEAT repeat HEAT_EZ PF13513.1 KLO19344.1 - 0.022 15.2 0.9 12 6.5 0.0 4.9 4 1 0 4 4 4 0 HEAT-like repeat PIP5K PF01504.13 KLO19345.1 - 4.8e-82 274.8 0.0 6.7e-82 274.3 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase Peptidase_S26 PF10502.4 KLO19345.1 - 0.14 11.6 0.0 0.4 10.2 0.0 1.8 2 0 0 2 2 2 0 Signal peptidase, peptidase S26 UDP-g_GGTase PF06427.6 KLO19346.1 - 1.4e-50 171.5 0.0 3.1e-50 170.4 0.0 1.5 1 0 0 1 1 1 1 UDP-glucose:Glycoprotein Glucosyltransferase Glyco_transf_8 PF01501.15 KLO19346.1 - 1.3e-07 31.2 0.1 2.4e-07 30.3 0.1 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 8 E1-E2_ATPase PF00122.15 KLO19347.1 - 1.3e-57 194.5 0.1 1.3e-57 194.5 0.1 2.1 2 1 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.21 KLO19347.1 - 2.7e-23 83.5 0.0 6.8e-23 82.2 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 KLO19347.1 - 8.6e-15 55.4 0.1 1.7e-14 54.4 0.1 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 KLO19347.1 - 3.6e-13 48.7 0.0 8e-13 47.6 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 KLO19347.1 - 1.9e-05 24.3 0.0 0.0003 20.4 0.1 2.5 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 KLO19347.1 - 0.16 11.9 0.0 0.35 10.8 0.0 1.6 1 0 0 1 1 1 0 Putative hydrolase of sodium-potassium ATPase alpha subunit Pkinase PF00069.20 KLO19350.1 - 2.7e-08 33.2 0.0 6.1e-08 32.1 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KLO19350.1 - 0.02 13.9 0.0 0.037 13.0 0.0 1.5 1 0 0 1 1 1 0 Protein tyrosine kinase Peptidase_C50 PF03568.12 KLO19352.1 - 2.7e-98 329.1 0.0 4.8e-98 328.3 0.0 1.4 1 0 0 1 1 1 1 Peptidase family C50 TPR_11 PF13414.1 KLO19352.1 - 2.6e-07 30.1 9.4 1.8 8.2 0.0 6.4 5 1 1 6 6 6 3 TPR repeat TPR_12 PF13424.1 KLO19352.1 - 8.7e-07 28.8 9.4 0.27 11.1 0.0 6.1 5 2 1 7 7 7 2 Tetratricopeptide repeat TPR_16 PF13432.1 KLO19352.1 - 0.0002 21.9 8.3 0.0016 19.0 0.0 5.7 5 1 1 6 6 6 1 Tetratricopeptide repeat TPR_2 PF07719.12 KLO19352.1 - 0.0012 18.5 16.8 12 6.1 0.1 7.5 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_14 PF13428.1 KLO19352.1 - 0.024 15.2 1.5 7.2 7.5 0.0 5.6 6 1 0 6 6 6 0 Tetratricopeptide repeat TPR_1 PF00515.23 KLO19352.1 - 0.047 13.3 9.2 13 5.5 0.1 5.7 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_8 PF13181.1 KLO19352.1 - 0.066 13.0 4.3 21 5.2 0.0 5.8 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_10 PF13374.1 KLO19352.1 - 0.17 11.8 1.5 11 6.1 0.0 3.9 3 0 0 3 3 3 0 Tetratricopeptide repeat adh_short PF00106.20 KLO19353.1 - 1.5e-15 57.4 0.0 2.1e-15 57.0 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KLO19353.1 - 1.9e-07 31.0 0.0 2e-07 31.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KLO19353.1 - 0.00043 20.0 0.0 0.00062 19.4 0.0 1.4 1 1 0 1 1 1 1 KR domain Epimerase PF01370.16 KLO19353.1 - 0.013 14.9 0.0 0.038 13.4 0.0 1.7 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 KLO19353.1 - 0.033 14.2 0.0 0.048 13.6 0.0 1.5 1 0 0 1 1 1 0 NADH(P)-binding Flo11 PF10182.4 KLO19353.1 - 0.13 11.8 0.0 0.19 11.2 0.0 1.2 1 0 0 1 1 1 0 Flo11 domain HECT_2 PF09814.4 KLO19354.1 - 1.9e-34 118.9 0.0 3e-34 118.3 0.0 1.3 1 0 0 1 1 1 1 HECT-like Ubiquitin-conjugating enzyme (E2)-binding P120R PF08062.6 KLO19354.1 - 0.22 11.8 1.4 0.65 10.3 1.0 1.9 1 0 0 1 1 1 0 P120R (NUC006) repeat GRAB PF10375.4 KLO19355.1 - 4.8e-07 29.1 1.0 1e-06 28.0 0.7 1.6 1 0 0 1 1 1 1 GRIP-related Arf-binding domain CENP-F_leu_zip PF10473.4 KLO19355.1 - 0.0082 16.0 25.5 0.0082 16.0 17.7 2.8 1 1 1 2 2 2 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 GRIP PF01465.15 KLO19355.1 - 0.049 13.1 0.0 0.11 12.0 0.0 1.6 1 0 0 1 1 1 0 GRIP domain Phage_GP20 PF06810.6 KLO19355.1 - 0.39 10.1 25.8 0.2 11.1 3.1 3.1 2 1 0 2 2 2 0 Phage minor structural protein GP20 LPP PF04728.8 KLO19355.1 - 0.54 10.0 5.8 1.1 9.1 1.3 2.4 2 0 0 2 2 2 0 Lipoprotein leucine-zipper DUF1054 PF06335.7 KLO19355.1 - 0.85 9.2 9.0 0.12 12.0 2.3 2.3 2 1 1 3 3 3 0 Protein of unknown function (DUF1054) AKNA PF12443.3 KLO19355.1 - 2.8 8.0 13.6 1.7 8.7 0.7 3.4 2 2 1 3 3 3 0 AT-hook-containing transcription factor DUF3584 PF12128.3 KLO19355.1 - 4.3 4.5 33.3 5.5 4.1 23.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) DUF745 PF05335.8 KLO19355.1 - 5.3 6.5 22.8 0.34 10.3 4.3 2.8 1 1 2 3 3 3 0 Protein of unknown function (DUF745) DUF667 PF05018.8 KLO19356.1 - 1.4e-21 76.6 0.0 1.8e-10 40.3 0.0 3.1 3 0 0 3 3 3 3 Protein of unknown function (DUF667) WD40 PF00400.27 KLO19357.1 - 4.4e-17 61.2 2.9 3.8e-07 29.7 0.0 5.3 5 0 0 5 5 5 3 WD domain, G-beta repeat SAPS PF04499.10 KLO19357.1 - 0.07 11.7 0.0 0.11 11.1 0.0 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein DUF3829 PF12889.2 KLO19357.1 - 0.073 12.2 0.6 1.6 7.8 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3829) Orthopox_F14 PF06076.7 KLO19357.1 - 0.11 12.5 1.8 0.18 11.8 0.4 2.0 2 0 0 2 2 2 0 Orthopoxvirus F14 protein FlgN PF05130.7 KLO19357.1 - 2.2 8.5 5.7 6.6 6.9 0.0 2.4 2 0 0 2 2 2 0 FlgN protein Amidase PF01425.16 KLO19358.1 - 3.3e-100 336.0 0.0 4e-100 335.7 0.0 1.1 1 0 0 1 1 1 1 Amidase Amidase PF01425.16 KLO19359.1 - 8e-98 328.1 0.0 9.4e-98 327.9 0.0 1.0 1 0 0 1 1 1 1 Amidase DUF3439 PF11921.3 KLO19359.1 - 0.036 13.8 0.0 0.087 12.5 0.0 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF3439) WD40 PF00400.27 KLO19360.1 - 8.2e-16 57.2 7.5 5.5e-07 29.2 0.0 5.5 5 0 0 5 5 5 3 WD domain, G-beta repeat Dor1 PF04124.7 KLO19360.1 - 0.041 12.3 0.2 0.17 10.2 0.0 1.9 2 0 0 2 2 2 0 Dor1-like family Iso_dh PF00180.15 KLO19361.1 - 8.9e-84 281.3 0.0 1e-83 281.2 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase IMS PF00817.15 KLO19361.1 - 0.039 13.7 0.0 0.067 12.9 0.0 1.3 1 0 0 1 1 1 0 impB/mucB/samB family WD40 PF00400.27 KLO19364.1 - 2.9e-11 42.7 7.4 1.5e-07 31.0 0.0 5.5 6 0 0 6 6 6 2 WD domain, G-beta repeat ABC_tran PF00005.22 KLO19365.1 - 2.3e-49 167.2 0.0 1.3e-29 103.2 0.0 2.4 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 KLO19365.1 - 4.4e-37 128.0 35.0 1.7e-21 76.8 7.0 3.9 4 0 0 4 4 4 2 ABC transporter transmembrane region SMC_N PF02463.14 KLO19365.1 - 3.1e-09 36.3 0.0 0.00068 18.9 0.6 3.3 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_25 PF13481.1 KLO19365.1 - 1.6e-06 27.6 0.1 0.033 13.6 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_21 PF13304.1 KLO19365.1 - 4.7e-05 23.4 0.2 0.53 10.1 0.1 3.7 2 1 0 2 2 2 1 AAA domain AAA_22 PF13401.1 KLO19365.1 - 0.00043 20.4 0.5 0.75 9.9 0.2 3.2 2 1 0 2 2 2 1 AAA domain AAA_10 PF12846.2 KLO19365.1 - 0.00063 19.2 0.1 0.23 10.8 0.0 2.6 2 1 0 2 2 2 1 AAA-like domain AAA_16 PF13191.1 KLO19365.1 - 0.00067 19.7 0.1 0.097 12.6 0.0 2.7 2 0 0 2 2 2 1 AAA ATPase domain T2SE PF00437.15 KLO19365.1 - 0.0018 17.2 0.0 0.19 10.5 0.0 2.3 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_29 PF13555.1 KLO19365.1 - 0.0035 16.8 1.1 0.27 10.8 0.1 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain DUF87 PF01935.12 KLO19365.1 - 0.013 15.3 0.1 0.035 13.9 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function DUF87 FtsK_SpoIIIE PF01580.13 KLO19365.1 - 0.017 14.5 0.0 2.6 7.4 0.0 2.5 2 0 0 2 2 2 0 FtsK/SpoIIIE family KaiC PF06745.8 KLO19365.1 - 0.019 14.1 0.0 2.1 7.3 0.0 2.4 2 0 0 2 2 2 0 KaiC AAA_23 PF13476.1 KLO19365.1 - 0.031 14.5 0.2 12 6.1 0.0 2.4 2 0 0 2 2 2 0 AAA domain Miro PF08477.8 KLO19365.1 - 0.06 13.8 0.2 27 5.2 0.0 3.0 2 0 0 2 2 2 0 Miro-like protein Zot PF05707.7 KLO19365.1 - 0.2 11.0 0.1 18 4.7 0.0 2.4 2 0 0 2 2 2 0 Zonular occludens toxin (Zot) Pox_A32 PF04665.7 KLO19365.1 - 0.24 10.6 0.9 8 5.6 0.1 2.3 2 0 0 2 2 2 0 Poxvirus A32 protein cobW PF02492.14 KLO19365.1 - 0.3 10.4 2.4 1.2 8.5 0.4 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain YqfD PF06898.6 KLO19365.1 - 0.95 8.0 1.8 4.5 5.8 0.5 2.1 2 0 0 2 2 2 0 Putative stage IV sporulation protein YqfD ABC_tran PF00005.22 KLO19366.1 - 7.8e-46 155.7 0.0 3.7e-27 95.2 0.0 2.7 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 KLO19366.1 - 3.4e-35 121.7 25.0 5e-22 78.5 4.0 2.8 3 0 0 3 3 3 2 ABC transporter transmembrane region SMC_N PF02463.14 KLO19366.1 - 2.4e-09 36.7 0.3 0.0014 17.8 0.0 2.8 2 1 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_25 PF13481.1 KLO19366.1 - 1.4e-06 27.8 0.0 0.01 15.2 0.0 2.5 2 0 0 2 2 2 2 AAA domain T2SE PF00437.15 KLO19366.1 - 6.8e-06 25.1 0.0 0.1 11.4 0.1 2.4 2 0 0 2 2 2 2 Type II/IV secretion system protein DUF87 PF01935.12 KLO19366.1 - 0.0013 18.6 2.3 0.053 13.3 0.1 2.8 3 0 0 3 3 3 1 Domain of unknown function DUF87 AAA_10 PF12846.2 KLO19366.1 - 0.0014 18.1 0.1 0.37 10.1 0.0 2.4 2 0 0 2 2 2 1 AAA-like domain FtsK_SpoIIIE PF01580.13 KLO19366.1 - 0.0031 16.9 0.0 1.4 8.3 0.0 2.5 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA_29 PF13555.1 KLO19366.1 - 0.0055 16.1 1.4 1.1 8.8 0.1 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_22 PF13401.1 KLO19366.1 - 0.015 15.4 3.6 4.7 7.3 0.1 3.3 2 1 0 2 2 2 0 AAA domain AAA_16 PF13191.1 KLO19366.1 - 0.036 14.0 0.4 7.7 6.4 0.0 2.6 2 0 0 2 2 2 0 AAA ATPase domain AAA_23 PF13476.1 KLO19366.1 - 0.053 13.8 2.0 3.2 8.0 0.0 2.7 3 0 0 3 3 2 0 AAA domain KaiC PF06745.8 KLO19366.1 - 0.064 12.3 0.5 3.5 6.6 0.0 2.3 2 0 0 2 2 2 0 KaiC DUF2075 PF09848.4 KLO19366.1 - 0.067 12.1 0.5 0.74 8.7 0.0 2.1 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) Pox_A32 PF04665.7 KLO19366.1 - 0.1 11.8 1.0 1.1 8.4 0.1 2.2 2 0 0 2 2 2 0 Poxvirus A32 protein DEAD PF00270.24 KLO19366.1 - 0.12 11.8 0.1 7.2 6.0 0.0 2.7 2 1 0 2 2 2 0 DEAD/DEAH box helicase NACHT PF05729.7 KLO19366.1 - 0.14 11.7 1.1 7.9 6.1 0.2 2.4 2 0 0 2 2 2 0 NACHT domain Miro PF08477.8 KLO19366.1 - 0.2 12.1 2.7 24 5.4 0.1 3.2 3 0 0 3 3 3 0 Miro-like protein AAA_17 PF13207.1 KLO19366.1 - 1.2 9.9 4.0 8.9 7.1 0.4 3.5 3 0 0 3 3 3 0 AAA domain MobB PF03205.9 KLO19366.1 - 2.4 7.8 3.9 23 4.6 0.0 3.1 3 0 0 3 3 3 0 Molybdopterin guanine dinucleotide synthesis protein B Methyltransf_16 PF10294.4 KLO19367.1 - 3.3e-11 42.9 0.0 6.7e-11 41.9 0.0 1.4 1 1 0 1 1 1 1 Putative methyltransferase PDEase_I PF00233.14 KLO19373.1 - 1.1e-42 146.4 0.9 8.5e-39 133.7 0.1 2.1 2 0 0 2 2 2 2 3'5'-cyclic nucleotide phosphodiesterase TENA_THI-4 PF03070.11 KLO19374.1 - 2e-15 57.1 0.2 2e-14 53.8 0.2 1.9 1 1 0 1 1 1 1 TENA/THI-4/PQQC family HCO3_cotransp PF00955.16 KLO19375.1 - 1.5e-54 185.5 8.7 4.4e-33 114.7 2.2 3.0 2 1 1 3 3 3 3 HCO3- transporter family MutS_V PF00488.16 KLO19376.1 - 1.5e-77 260.1 0.0 2.6e-77 259.4 0.0 1.4 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 KLO19376.1 - 3.9e-44 150.9 0.1 7e-44 150.0 0.1 1.5 1 0 0 1 1 1 1 MutS domain III MutS_I PF01624.15 KLO19376.1 - 6.3e-32 109.9 0.1 1.3e-31 108.8 0.0 1.6 1 0 0 1 1 1 1 MutS domain I MutS_II PF05188.12 KLO19376.1 - 9.3e-11 41.9 0.0 3.3e-10 40.1 0.0 2.0 1 0 0 1 1 1 1 MutS domain II MutS_IV PF05190.13 KLO19376.1 - 4.9e-05 23.4 0.1 0.00014 21.9 0.0 1.9 2 0 0 2 2 2 1 MutS family domain IV Formyl_trans_N PF00551.14 KLO19377.1 - 2.2e-26 92.5 0.0 3.4e-26 91.9 0.0 1.3 1 0 0 1 1 1 1 Formyl transferase Formyl_trans_C PF02911.13 KLO19377.1 - 1.2e-06 28.5 0.0 2e-06 27.8 0.0 1.4 1 0 0 1 1 1 1 Formyl transferase, C-terminal domain Asp PF00026.18 KLO19378.1 - 3.8e-33 115.0 3.7 5.2e-25 88.3 2.4 2.1 2 0 0 2 2 2 2 Eukaryotic aspartyl protease TAXi_N PF14543.1 KLO19378.1 - 1.4e-06 28.3 3.3 3.3e-06 27.1 2.3 1.6 1 0 0 1 1 1 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 KLO19378.1 - 0.0054 17.2 0.2 0.51 10.8 0.0 3.0 2 0 0 2 2 2 1 Aspartyl protease CBM_X PF06204.6 KLO19378.1 - 0.083 12.3 0.2 0.28 10.6 0.1 1.9 1 0 0 1 1 1 0 Putative carbohydrate binding domain DUF3584 PF12128.3 KLO19379.1 - 0.057 10.7 16.8 0.097 9.9 11.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) NIF PF03031.13 KLO19380.1 - 0.11 12.1 0.1 10 5.7 0.1 2.2 1 1 1 2 2 2 0 NLI interacting factor-like phosphatase DNA_primase_S PF01896.14 KLO19383.1 - 1.1e-49 168.0 0.1 1.6e-49 167.4 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic and archaeal DNA primase small subunit HHH_5 PF14520.1 KLO19384.1 - 0.056 13.6 0.0 0.17 12.1 0.0 1.8 1 0 0 1 1 1 0 Helix-hairpin-helix domain KaiC PF06745.8 KLO19384.1 - 0.2 10.7 0.1 5.3 6.0 0.0 2.1 1 1 0 1 1 1 0 KaiC 5-FTHF_cyc-lig PF01812.15 KLO19385.1 - 7.8e-40 136.6 0.0 9.4e-40 136.3 0.0 1.1 1 0 0 1 1 1 1 5-formyltetrahydrofolate cyclo-ligase family Tagatose_6_P_K PF08013.6 KLO19389.1 - 0.077 11.4 0.0 0.11 10.9 0.0 1.2 1 0 0 1 1 1 0 Tagatose 6 phosphate kinase zf-C2H2 PF00096.21 KLO19390.1 - 1.8e-09 37.3 6.3 6.7e-05 22.9 0.4 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 KLO19390.1 - 3.1e-09 36.6 5.3 2.7e-05 24.2 0.1 3.3 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 KLO19390.1 - 1e-08 34.9 4.5 0.00061 19.9 0.2 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 KLO19390.1 - 1.4e-06 28.2 0.4 0.003 17.6 0.0 2.7 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 KLO19390.1 - 6.6e-06 26.1 1.1 0.0026 17.9 0.0 2.8 2 0 0 2 2 2 2 Zinc-finger of C2H2 type PRP21_like_P PF12230.3 KLO19390.1 - 0.059 12.8 0.6 0.11 11.9 0.4 1.4 1 0 0 1 1 1 0 Pre-mRNA splicing factor PRP21 like protein zf-C2H2_6 PF13912.1 KLO19390.1 - 0.14 12.1 0.2 0.75 9.7 0.0 2.2 2 0 0 2 2 2 0 C2H2-type zinc finger PIG-P PF08510.7 KLO19391.1 - 1.9e-31 108.3 3.3 2.3e-31 108.0 2.3 1.1 1 0 0 1 1 1 1 PIG-P Corona_M PF01635.13 KLO19391.1 - 1.7 7.5 7.8 2.2 7.1 5.4 1.1 1 0 0 1 1 1 0 Coronavirus M matrix/glycoprotein YibE_F PF07907.6 KLO19393.1 - 0.0061 15.7 0.3 0.0061 15.7 0.2 1.8 2 0 0 2 2 2 1 YibE/F-like protein ICMT PF04140.9 KLO19395.1 - 3.2e-10 40.0 0.9 8.7e-10 38.6 0.1 2.1 2 0 0 2 2 2 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family ERG4_ERG24 PF01222.12 KLO19395.1 - 3.7e-08 32.3 0.0 7.7e-08 31.2 0.0 1.5 1 1 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family PEMT PF04191.8 KLO19395.1 - 5.9e-08 32.7 5.7 2e-07 31.0 0.4 2.8 3 0 0 3 3 3 1 Phospholipid methyltransferase HAD_2 PF13419.1 KLO19396.1 - 2.7e-32 112.4 0.0 3.3e-32 112.1 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 KLO19396.1 - 0.0044 17.4 0.0 0.068 13.5 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 KLO19396.1 - 0.0052 16.4 0.0 0.011 15.4 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like EXS PF03124.9 KLO19397.1 - 5.7e-62 209.7 15.6 6.5e-62 209.5 10.8 1.0 1 0 0 1 1 1 1 EXS family Vps16_C PF04840.7 KLO19398.1 - 2.9e-86 289.3 0.1 3.7e-86 288.9 0.1 1.1 1 0 0 1 1 1 1 Vps16, C-terminal region Vps16_N PF04841.8 KLO19398.1 - 2.5e-82 276.6 0.0 4.1e-82 275.9 0.0 1.3 1 0 0 1 1 1 1 Vps16, N-terminal region Peptidase_C48 PF02902.14 KLO19401.1 - 0.028 14.0 0.5 0.067 12.8 0.3 1.7 1 1 0 1 1 1 0 Ulp1 protease family, C-terminal catalytic domain FANCI_S4 PF14678.1 KLO19401.1 - 0.039 13.0 0.4 0.22 10.6 0.0 2.1 2 0 0 2 2 2 0 FANCI solenoid 4 DUF2076 PF09849.4 KLO19402.1 - 9.5e-07 29.1 10.3 1.3e-06 28.6 7.2 1.2 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2076) CHCH PF06747.8 KLO19402.1 - 1.3e-05 24.9 0.3 2.1e-05 24.3 0.2 1.3 1 0 0 1 1 1 1 CHCH domain Rick_17kDa_Anti PF05433.10 KLO19402.1 - 0.029 14.0 2.5 0.054 13.1 1.8 1.4 1 0 0 1 1 1 0 Glycine zipper 2TM domain DUF605 PF04652.11 KLO19402.1 - 2.7 7.2 11.8 3.6 6.9 8.2 1.3 1 0 0 1 1 1 0 Vta1 like TPR_14 PF13428.1 KLO19403.1 - 0.1 13.2 1.5 32 5.5 0.4 3.1 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_7 PF13176.1 KLO19403.1 - 0.1 12.4 0.9 10 6.1 0.0 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.1 KLO19403.1 - 0.14 12.0 1.6 3.4 7.6 0.2 2.9 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.1 KLO19404.1 - 3.9e-05 23.4 6.1 0.03 14.2 0.0 3.6 2 2 1 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.12 KLO19404.1 - 0.00077 19.1 1.6 1.5 8.9 0.3 3.2 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.1 KLO19404.1 - 0.0015 18.1 0.2 0.19 11.5 0.0 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_11 PF13414.1 KLO19404.1 - 0.009 15.6 4.1 1.3 8.7 0.1 3.5 3 0 0 3 3 3 2 TPR repeat TPR_14 PF13428.1 KLO19404.1 - 0.015 15.9 3.3 3.8 8.4 0.3 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat MIT PF04212.13 KLO19404.1 - 0.033 14.0 1.2 8.9 6.2 0.0 3.0 3 0 0 3 3 3 0 MIT (microtubule interacting and transport) domain TPR_8 PF13181.1 KLO19404.1 - 0.22 11.4 1.8 7.3 6.6 0.0 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.23 KLO19404.1 - 2 8.1 9.1 0.57 9.8 0.1 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat Sec62 PF03839.11 KLO19405.1 - 1.9e-48 164.8 3.5 2.5e-47 161.1 0.9 2.0 2 0 0 2 2 2 2 Translocation protein Sec62 DUF3413 PF11893.3 KLO19405.1 - 1.6 7.5 6.5 2.4 6.9 4.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3413) RNA_pol_N PF01194.12 KLO19406.1 - 8.9e-31 105.7 0.2 1.1e-30 105.4 0.1 1.1 1 0 0 1 1 1 1 RNA polymerases N / 8 kDa subunit NMD3 PF04981.8 KLO19407.1 - 1.1e-74 250.5 0.7 1.4e-74 250.1 0.5 1.2 1 0 0 1 1 1 1 NMD3 family zf-dskA_traR PF01258.12 KLO19407.1 - 0.45 10.2 3.0 0.24 11.1 0.1 2.1 2 0 0 2 2 2 0 Prokaryotic dksA/traR C4-type zinc finger DZR PF12773.2 KLO19407.1 - 1.3 8.9 7.0 7.8 6.4 3.7 2.6 2 1 0 2 2 2 0 Double zinc ribbon NinF PF05810.7 KLO19407.1 - 1.8 8.3 6.3 0.28 10.9 0.6 2.4 3 0 0 3 3 3 0 NinF protein Malic_M PF03949.10 KLO19410.1 - 3.5e-85 285.6 0.0 4.4e-85 285.2 0.0 1.1 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.14 KLO19410.1 - 2.5e-62 209.7 0.0 3.7e-62 209.1 0.0 1.2 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain EphA2_TM PF14575.1 KLO19412.1 - 0.028 14.8 0.0 0.058 13.7 0.0 1.4 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Herpes_gE PF02480.11 KLO19412.1 - 0.034 12.4 0.0 0.034 12.4 0.0 1.8 2 0 0 2 2 2 0 Alphaherpesvirus glycoprotein E TMEM154 PF15102.1 KLO19412.1 - 0.33 10.6 9.3 3.2 7.4 6.4 2.3 1 1 0 1 1 1 0 TMEM154 protein family RabGAP-TBC PF00566.13 KLO19413.1 - 1e-21 77.4 0.0 1.7e-21 76.7 0.0 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain HbrB PF08539.6 KLO19414.1 - 6.5e-27 94.3 0.0 7.9e-27 94.0 0.0 1.0 1 0 0 1 1 1 1 HbrB-like Sec7 PF01369.15 KLO19415.1 - 3.6e-23 82.2 0.0 6.6e-23 81.3 0.0 1.4 1 0 0 1 1 1 1 Sec7 domain Erf4 PF10256.4 KLO19416.1 - 0.0015 18.3 0.0 0.0029 17.4 0.0 1.4 1 0 0 1 1 1 1 Golgin subfamily A member 7/ERF4 family Erf4 PF10256.4 KLO19417.1 - 0.00036 20.3 0.0 0.00069 19.4 0.0 1.4 1 0 0 1 1 1 1 Golgin subfamily A member 7/ERF4 family DUF1823 PF08853.6 KLO19417.1 - 0.041 13.6 0.2 0.078 12.7 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1823) Erf4 PF10256.4 KLO19418.1 - 0.021 14.7 0.0 0.053 13.3 0.0 1.6 2 0 0 2 2 2 0 Golgin subfamily A member 7/ERF4 family DUF3712 PF12505.3 KLO19419.1 - 8.7e-107 352.1 74.0 1.7e-24 86.2 2.2 10.2 11 0 0 11 11 11 6 Protein of unknown function (DUF3712) LEA_2 PF03168.8 KLO19419.1 - 2.7e-11 43.7 17.8 0.17 12.2 0.0 9.5 9 0 0 9 9 9 5 Late embryogenesis abundant protein Acyltransferase PF01553.16 KLO19420.1 - 3.6e-12 45.8 0.0 5.8e-12 45.1 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase DUF1129 PF06570.6 KLO19421.1 - 0.0064 15.8 3.8 0.041 13.1 0.1 2.7 3 0 0 3 3 3 1 Protein of unknown function (DUF1129) DUF1469 PF07332.6 KLO19421.1 - 0.037 13.7 0.2 0.037 13.7 0.2 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF1469) DUF872 PF05915.7 KLO19421.1 - 0.11 12.3 0.0 0.24 11.2 0.0 1.6 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF872) Ctr PF04145.10 KLO19421.1 - 0.55 10.2 3.5 0.22 11.5 0.1 2.0 2 1 1 3 3 3 0 Ctr copper transporter family DUF202 PF02656.10 KLO19421.1 - 1.1 9.4 5.3 1.7 8.8 1.1 2.7 1 1 1 2 2 2 0 Domain of unknown function (DUF202) DUF1218 PF06749.7 KLO19422.1 - 0.0033 17.8 3.5 0.3 11.5 0.2 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF1218) DUF1129 PF06570.6 KLO19422.1 - 0.0052 16.1 1.5 0.4 9.9 0.1 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF1129) Cation_ATPase_C PF00689.16 KLO19422.1 - 0.0057 16.1 3.3 0.091 12.2 0.5 2.1 2 0 0 2 2 2 2 Cation transporting ATPase, C-terminus DUF872 PF05915.7 KLO19422.1 - 0.064 13.1 0.1 0.19 11.6 0.0 1.8 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF872) DUF872 PF05915.7 KLO19424.1 - 0.026 14.3 0.2 0.07 12.9 0.1 1.7 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF872) PGBA_C PF15437.1 KLO19424.1 - 1.5 8.9 12.7 2.4 8.3 7.7 2.2 1 1 1 2 2 2 0 Plasminogen-binding protein pgbA C-terminal NUC173 PF08161.7 KLO19425.1 - 2.1e-36 125.1 0.0 3.7e-34 117.8 0.0 2.9 2 0 0 2 2 2 2 NUC173 domain Cnd1 PF12717.2 KLO19425.1 - 4.5e-05 23.3 0.1 0.065 13.0 0.1 3.3 3 0 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.1 KLO19425.1 - 0.0084 16.3 3.4 0.32 11.3 0.0 4.5 4 1 0 4 4 4 1 HEAT repeats Elongin_A PF06881.6 KLO19425.1 - 0.055 13.8 0.6 0.13 12.6 0.4 1.6 1 0 0 1 1 1 0 RNA polymerase II transcription factor SIII (Elongin) subunit A Acyltransferase PF01553.16 KLO19426.1 - 5.6e-14 51.7 0.0 8.2e-13 47.9 0.0 2.2 2 0 0 2 2 2 1 Acyltransferase NdhL PF10716.4 KLO19426.1 - 0.047 13.4 6.8 1.5 8.6 0.4 2.5 2 0 0 2 2 2 0 NADH dehydrogenase transmembrane subunit DBP10CT PF08147.7 KLO19427.1 - 1.3e-19 69.7 4.2 3.4e-19 68.4 2.9 1.8 1 0 0 1 1 1 1 DBP10CT (NUC160) domain Helicase_C PF00271.26 KLO19427.1 - 2.1e-19 69.1 0.1 1.3e-18 66.5 0.0 2.4 3 0 0 3 3 3 1 Helicase conserved C-terminal domain DEAD PF00270.24 KLO19427.1 - 1.9e-16 60.0 0.5 5.4e-14 52.0 0.0 3.0 2 1 1 3 3 3 2 DEAD/DEAH box helicase IMS PF00817.15 KLO19428.1 - 1.5e-39 135.1 0.0 3.1e-39 134.1 0.0 1.5 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.3 KLO19428.1 - 2.6e-14 53.2 0.1 8.1e-14 51.6 0.0 1.8 2 0 0 2 2 2 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.3 KLO19428.1 - 3.6e-08 32.9 0.0 9.7e-08 31.6 0.0 1.8 1 0 0 1 1 1 1 IMS family HHH motif Choline_transpo PF04515.7 KLO19429.1 - 2.4e-72 243.5 13.7 2.4e-72 243.5 9.5 2.1 2 0 0 2 2 2 1 Plasma-membrane choline transporter XPC-binding PF09280.6 KLO19429.1 - 0.15 11.5 0.5 0.86 9.1 0.1 2.2 2 0 0 2 2 2 0 XPC-binding domain TMEMspv1-c74-12 PF11044.3 KLO19429.1 - 7.5 6.1 11.2 4.2 6.9 1.6 3.0 1 1 1 2 2 2 0 Plectrovirus spv1-c74 ORF 12 transmembrane protein Glyco_hydro_16 PF00722.16 KLO19430.1 - 3.1e-20 72.2 0.9 6.5e-19 67.9 0.1 2.3 1 1 1 2 2 2 2 Glycosyl hydrolases family 16 Ssl1 PF04056.9 KLO19431.1 - 6.5e-70 234.6 0.0 1e-69 234.0 0.0 1.3 1 0 0 1 1 1 1 Ssl1-like C1_4 PF07975.7 KLO19431.1 - 4.3e-15 55.4 12.7 4.3e-15 55.4 8.8 3.1 3 0 0 3 3 3 1 TFIIH C1-like domain VWA_2 PF13519.1 KLO19431.1 - 8e-12 45.5 0.0 1.3e-11 44.9 0.0 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain Tfb4 PF03850.9 KLO19431.1 - 0.011 15.0 2.7 10 5.2 0.0 2.4 2 1 0 2 2 2 0 Transcription factor Tfb4 VWA PF00092.23 KLO19431.1 - 0.14 11.8 0.0 0.23 11.1 0.0 1.4 1 1 0 1 1 1 0 von Willebrand factor type A domain IBR PF01485.16 KLO19431.1 - 5.3 6.9 18.7 0.072 12.9 5.8 2.4 2 0 0 2 2 2 0 IBR domain SAM_decarbox PF01536.11 KLO19432.1 - 4.5e-83 278.6 0.0 2.9e-54 183.9 0.0 3.1 2 1 1 3 3 3 3 Adenosylmethionine decarboxylase PP2C PF00481.16 KLO19433.1 - 1.2e-19 70.6 0.0 1.4e-17 63.9 0.0 2.2 1 1 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.1 KLO19433.1 - 1e-05 25.0 0.0 2.9e-05 23.5 0.0 1.7 1 1 0 1 1 1 1 Protein phosphatase 2C zf-U1 PF06220.7 KLO19434.1 - 7.1e-10 38.2 1.0 1.2e-09 37.5 0.7 1.4 1 0 0 1 1 1 1 U1 zinc finger MAGE_N PF12440.3 KLO19434.1 - 0.0088 16.3 4.4 0.0088 16.3 3.0 3.1 3 1 0 3 3 3 1 Melanoma associated antigen family N terminal zf-C2H2_jaz PF12171.3 KLO19434.1 - 0.76 10.0 3.9 3 8.0 2.7 2.0 1 1 0 1 1 1 0 Zinc-finger double-stranded RNA-binding CTP_transf_1 PF01148.15 KLO19435.1 - 3.5e-76 256.3 22.4 4.5e-76 255.9 15.5 1.1 1 0 0 1 1 1 1 Cytidylyltransferase family Ribosom_S12_S23 PF00164.20 KLO19436.1 - 1.4e-36 124.6 0.3 1.6e-36 124.3 0.2 1.1 1 0 0 1 1 1 1 Ribosomal protein S12/S23 Ribosom_S12_S23 PF00164.20 KLO19437.1 - 2e-38 130.5 0.5 2.3e-38 130.3 0.3 1.1 1 0 0 1 1 1 1 Ribosomal protein S12/S23 Abhydrolase_1 PF00561.15 KLO19438.1 - 7.1e-17 61.7 0.3 1.7e-16 60.5 0.2 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 KLO19438.1 - 3.3e-16 59.8 0.0 4.1e-16 59.5 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KLO19438.1 - 0.0045 16.7 0.0 0.018 14.8 0.0 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.15 KLO19438.1 - 0.018 14.4 0.0 0.026 13.9 0.0 1.3 1 0 0 1 1 1 0 Putative esterase Abhydrolase_1 PF00561.15 KLO19439.1 - 9e-14 51.5 0.1 1.5e-13 50.8 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 KLO19439.1 - 2.4e-09 37.4 0.0 3.5e-09 36.8 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KLO19439.1 - 0.041 13.6 0.0 0.43 10.3 0.0 2.2 1 1 0 1 1 1 0 Alpha/beta hydrolase family EMP70 PF02990.11 KLO19440.1 - 2.2e-178 593.9 0.0 2.9e-178 593.5 0.0 1.1 1 0 0 1 1 1 1 Endomembrane protein 70 tRNA-synt_1b PF00579.20 KLO19441.1 - 4.8e-75 252.3 0.0 7e-75 251.8 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) S4 PF01479.20 KLO19441.1 - 0.04 13.3 0.0 0.081 12.3 0.0 1.5 1 0 0 1 1 1 0 S4 domain TGT PF01702.13 KLO19442.1 - 6.6e-83 277.6 0.0 1e-82 277.0 0.0 1.3 1 0 0 1 1 1 1 Queuine tRNA-ribosyltransferase RCC1 PF00415.13 KLO19443.1 - 9.3e-21 73.7 6.4 2.8e-08 33.8 0.0 7.6 8 0 0 8 8 8 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 KLO19443.1 - 5.3e-08 32.2 13.0 0.0037 16.8 0.1 5.7 5 0 0 5 5 5 2 Regulator of chromosome condensation (RCC1) repeat WD40 PF00400.27 KLO19444.1 - 2.7e-127 410.6 53.1 1.2e-14 53.4 0.0 15.2 14 1 0 14 14 14 14 WD domain, G-beta repeat eIF2A PF08662.6 KLO19444.1 - 2.1e-14 53.6 0.0 0.037 13.7 0.1 5.6 2 2 3 6 6 6 5 Eukaryotic translation initiation factor eIF2A Nucleoporin_N PF08801.6 KLO19444.1 - 3.9e-12 45.6 8.4 0.25 10.0 0.0 7.3 1 1 5 7 7 7 6 Nup133 N terminal like PD40 PF07676.7 KLO19444.1 - 1.6e-07 30.8 5.3 5.9 6.6 0.0 8.3 9 0 0 9 9 9 1 WD40-like Beta Propeller Repeat Cytochrom_D1 PF02239.11 KLO19444.1 - 2e-05 23.1 0.3 0.41 8.8 0.0 3.7 4 0 0 4 4 4 3 Cytochrome D1 heme domain Nbas_N PF15492.1 KLO19444.1 - 0.00041 19.5 11.5 3.4 6.6 0.0 8.1 7 2 4 12 12 12 1 Neuroblastoma-amplified sequence, N terminal AAA_16 PF13191.1 KLO19444.1 - 0.0012 18.8 0.0 0.0043 17.0 0.0 1.9 1 1 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.1 KLO19444.1 - 0.063 12.8 0.1 0.23 10.9 0.1 1.9 1 0 0 1 1 1 0 P-loop containing region of AAA domain Mg_chelatase PF01078.16 KLO19444.1 - 0.081 12.0 0.4 0.16 11.0 0.3 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_18 PF13238.1 KLO19444.1 - 0.092 13.0 0.0 0.2 11.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.1 KLO19444.1 - 0.1 13.3 0.1 0.39 11.5 0.0 2.0 2 1 0 2 2 1 0 AAA domain AAA PF00004.24 KLO19444.1 - 0.13 12.5 0.0 0.6 10.3 0.0 2.1 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_23 PF13476.1 KLO19444.1 - 0.17 12.2 0.1 0.35 11.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain APS_kinase PF01583.15 KLO19444.1 - 0.17 11.5 0.2 0.29 10.7 0.2 1.3 1 0 0 1 1 1 0 Adenylylsulphate kinase Proteasome_A_N PF10584.4 KLO19444.1 - 7.1 6.0 20.7 4.3 6.7 0.0 8.0 11 0 0 11 11 11 0 Proteasome subunit A N-terminal signature DASH_Duo1 PF08651.5 KLO19445.1 - 2e-13 49.6 0.2 3.3e-13 48.9 0.1 1.3 1 0 0 1 1 1 1 DASH complex subunit Duo1 HrpA_pilin PF09589.5 KLO19445.1 - 0.019 15.4 0.0 0.085 13.2 0.0 2.0 1 1 0 1 1 1 0 HrpA pilus formation protein MAP7 PF05672.6 KLO19445.1 - 0.12 11.7 39.8 0.041 13.2 19.1 2.2 2 0 0 2 2 2 0 MAP7 (E-MAP-115) family ATG27 PF09451.5 KLO19446.1 - 1.5e-47 162.1 0.0 1.8e-47 161.8 0.0 1.0 1 0 0 1 1 1 1 Autophagy-related protein 27 Man-6-P_recep PF02157.10 KLO19446.1 - 0.0096 14.9 0.0 0.016 14.1 0.0 1.3 1 0 0 1 1 1 1 Mannose-6-phosphate receptor Josephin PF02099.12 KLO19447.1 - 6.8e-50 168.7 0.3 1.1e-49 168.0 0.2 1.3 1 0 0 1 1 1 1 Josephin UIM PF02809.15 KLO19447.1 - 5.7e-05 22.3 7.6 0.00017 20.8 0.6 5.2 5 0 0 5 5 5 3 Ubiquitin interaction motif Pyridox_oxidase PF01243.15 KLO19448.1 - 3.5e-10 39.7 0.0 1e-09 38.2 0.0 1.7 2 0 0 2 2 2 1 Pyridoxamine 5'-phosphate oxidase PP2C PF00481.16 KLO19449.1 - 3.6e-23 82.2 0.0 1.4e-15 57.4 0.0 3.1 2 1 0 3 3 3 3 Protein phosphatase 2C PP2C_2 PF13672.1 KLO19449.1 - 8.4e-07 28.6 0.3 5.8e-05 22.6 0.1 2.4 2 0 0 2 2 2 1 Protein phosphatase 2C HTH_Tnp_Mu_1 PF02316.11 KLO19449.1 - 0.035 13.8 0.0 0.071 12.8 0.0 1.4 1 0 0 1 1 1 0 Mu DNA-binding domain SpoIIE PF07228.7 KLO19449.1 - 0.047 13.3 1.5 0.096 12.3 0.1 2.1 2 1 0 2 2 2 0 Stage II sporulation protein E (SpoIIE) SWIM PF04434.12 KLO19454.1 - 2.8e-07 29.8 0.1 4.9e-07 29.0 0.0 1.4 1 0 0 1 1 1 1 SWIM zinc finger RCC1 PF00415.13 KLO19455.1 - 3e-35 120.1 2.1 4.4e-11 42.8 0.0 5.5 5 0 0 5 5 5 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 KLO19455.1 - 3.2e-16 58.4 9.9 1.5e-05 24.4 0.1 4.7 5 0 0 5 5 5 3 Regulator of chromosome condensation (RCC1) repeat PHD PF00628.24 KLO19455.1 - 1.1e-10 41.0 3.8 2e-10 40.1 2.7 1.5 1 0 0 1 1 1 1 PHD-finger Prok-RING_1 PF14446.1 KLO19455.1 - 0.01 15.5 2.3 0.01 15.5 1.6 1.9 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 C1_1 PF00130.17 KLO19455.1 - 0.019 14.6 0.1 0.047 13.4 0.1 1.6 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Peptidase_S10 PF00450.17 KLO19457.1 - 4.7e-91 306.0 6.9 6.3e-91 305.5 4.8 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Abhydrolase_5 PF12695.2 KLO19457.1 - 0.11 12.2 0.0 0.29 10.9 0.0 1.7 1 1 0 1 1 1 0 Alpha/beta hydrolase family MCM PF00493.18 KLO19458.1 - 1.3e-139 464.6 0.1 2e-139 464.0 0.1 1.3 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 KLO19458.1 - 2.3e-15 57.1 0.1 6.6e-15 55.6 0.0 1.8 1 0 0 1 1 1 1 MCM N-terminal domain MCM2_N PF12619.3 KLO19458.1 - 4.8e-11 42.8 14.3 4.8e-11 42.8 9.9 2.5 3 0 0 3 3 3 1 Mini-chromosome maintenance protein 2 Mg_chelatase PF01078.16 KLO19458.1 - 7.2e-08 31.8 0.0 2.6e-06 26.7 0.0 2.4 1 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 KLO19458.1 - 1.1e-05 25.2 0.0 2.3e-05 24.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 KLO19458.1 - 6.9e-05 22.4 0.1 0.0039 16.7 0.0 2.6 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 KLO19458.1 - 0.0014 18.0 0.1 0.015 14.8 0.0 2.2 1 1 0 1 1 1 1 Sigma-54 interaction domain GatB_Yqey PF02637.13 KLO19458.1 - 0.078 12.6 0.3 4.3 7.0 0.1 2.8 2 1 0 2 2 2 0 GatB domain Elf1 PF05129.8 KLO19458.1 - 0.088 12.5 0.4 0.2 11.3 0.3 1.5 1 0 0 1 1 1 0 Transcription elongation factor Elf1 like Thyroglobulin_1 PF00086.13 KLO19458.1 - 0.093 12.0 0.5 0.2 11.0 0.4 1.5 1 0 0 1 1 1 0 Thyroglobulin type-1 repeat Zn_ribbon_2 PF12674.2 KLO19458.1 - 0.12 12.7 0.8 0.34 11.2 0.5 1.7 1 0 0 1 1 1 0 Putative zinc ribbon domain UPF0020 PF01170.13 KLO19459.1 - 1.1e-12 47.8 0.0 1.9e-12 47.0 0.0 1.4 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_26 PF13659.1 KLO19459.1 - 3.9e-12 46.2 0.0 1.1e-11 44.8 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain N6_N4_Mtase PF01555.13 KLO19459.1 - 4e-06 26.4 0.0 0.074 12.5 0.0 2.3 2 0 0 2 2 2 2 DNA methylase N6_Mtase PF02384.11 KLO19459.1 - 0.015 14.4 0.0 0.27 10.2 0.0 2.1 2 0 0 2 2 2 0 N-6 DNA Methylase NDUF_B12 PF08122.7 KLO19460.1 - 5.3e-21 74.1 1.1 5.8e-21 73.9 0.7 1.0 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B12 subunit family Topoisom_I_N PF02919.10 KLO19461.1 - 6.4e-95 316.5 0.2 6.4e-95 316.5 0.1 4.1 3 2 2 5 5 5 1 Eukaryotic DNA topoisomerase I, DNA binding fragment Topoisom_I PF01028.15 KLO19461.1 - 1.5e-87 292.5 9.3 4.1e-87 291.1 6.5 1.8 1 0 0 1 1 1 1 Eukaryotic DNA topoisomerase I, catalytic core Topo_C_assoc PF14370.1 KLO19461.1 - 2.9e-32 110.1 0.2 2.9e-32 110.1 0.1 2.1 2 0 0 2 2 2 1 C-terminal topoisomerase domain DUF1947 PF09183.5 KLO19461.1 - 0.0058 16.3 0.1 0.028 14.1 0.1 2.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1947) Ctr PF04145.10 KLO19462.1 - 0.018 15.1 1.2 0.15 12.0 0.0 2.5 2 0 0 2 2 2 0 Ctr copper transporter family PepSY_TM_2 PF13703.1 KLO19462.1 - 1.6 8.9 4.8 0.33 11.1 0.3 1.9 2 0 0 2 2 2 0 PepSY-associated TM helix Glycophorin_A PF01102.13 KLO19464.1 - 0.00017 21.3 1.2 0.00017 21.3 0.8 1.8 2 0 0 2 2 2 1 Glycophorin A Shisa PF13908.1 KLO19464.1 - 0.041 14.0 0.4 0.15 12.2 0.0 1.9 1 1 1 2 2 2 0 Wnt and FGF inhibitory regulator Rifin_STEVOR PF02009.11 KLO19464.1 - 0.042 13.4 0.0 0.056 13.0 0.0 1.1 1 0 0 1 1 1 0 Rifin/stevor family Amnionless PF14828.1 KLO19464.1 - 0.085 11.3 0.0 0.11 10.9 0.0 1.1 1 0 0 1 1 1 0 Amnionless DUF2207 PF09972.4 KLO19464.1 - 0.11 11.0 0.0 0.13 10.7 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF202 PF02656.10 KLO19464.1 - 1.5 9.0 5.7 7.6 6.8 3.9 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF202) Ashwin PF15323.1 KLO19464.1 - 2.9 7.8 5.7 5.3 6.9 4.0 1.3 1 0 0 1 1 1 0 Developmental protein Macoilin PF09726.4 KLO19464.1 - 5.2 5.2 6.2 6.8 4.8 4.3 1.1 1 0 0 1 1 1 0 Transmembrane protein Glycophorin_A PF01102.13 KLO19465.1 - 0.85 9.3 20.9 0.03 14.0 9.0 2.5 2 1 0 2 2 2 0 Glycophorin A Macoilin PF09726.4 KLO19465.1 - 1.1 7.4 2.4 1.4 7.1 1.7 1.1 1 0 0 1 1 1 0 Transmembrane protein Adeno_E3_CR2 PF02439.10 KLO19466.1 - 0.058 12.9 0.9 0.11 12.0 0.6 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 DUF515 PF04415.7 KLO19466.1 - 4.8 5.3 8.9 7.4 4.7 6.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF515) Glyco_hydro_28 PF00295.12 KLO19467.1 - 1.7e-40 138.9 0.4 3.3e-40 138.0 0.3 1.4 1 1 0 1 1 1 1 Glycosyl hydrolases family 28 NosD PF05048.8 KLO19467.1 - 0.0049 16.0 4.1 0.0076 15.4 2.8 1.2 1 0 0 1 1 1 1 Periplasmic copper-binding protein (NosD) PEPCK_ATP PF01293.15 KLO19468.1 - 7.1e-215 713.8 0.0 8.4e-215 713.6 0.0 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase AAA_29 PF13555.1 KLO19468.1 - 0.037 13.5 0.0 0.087 12.3 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_33 PF13671.1 KLO19468.1 - 0.056 13.3 0.0 0.09 12.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.1 KLO19468.1 - 0.15 11.4 0.0 0.26 10.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.1 KLO19468.1 - 0.2 11.6 0.0 0.39 10.6 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain PP2C PF00481.16 KLO19471.1 - 1.2e-65 221.4 0.3 8.9e-52 176.0 0.0 2.1 2 0 0 2 2 2 2 Protein phosphatase 2C Scs3p PF10261.4 KLO19472.1 - 6.5e-39 133.3 15.4 2.7e-36 124.8 10.7 2.9 1 1 0 1 1 1 1 Inositol phospholipid synthesis and fat-storage-inducing TM PAP2 PF01569.16 KLO19472.1 - 0.00021 20.9 1.0 0.00021 20.9 0.7 2.2 2 1 0 2 2 2 1 PAP2 superfamily EamA PF00892.15 KLO19472.1 - 8.5 6.4 13.0 0.08 12.9 1.6 2.6 3 1 0 3 3 3 0 EamA-like transporter family zf-MYND PF01753.13 KLO19473.1 - 3e-08 33.4 13.6 3e-08 33.4 9.4 3.0 3 1 0 3 3 3 2 MYND finger zf-MYND PF01753.13 KLO19474.1 - 8.6e-09 35.1 17.9 8.4e-08 31.9 11.9 2.3 1 1 1 2 2 2 1 MYND finger OrfB_Zn_ribbon PF07282.6 KLO19474.1 - 0.025 14.2 2.9 0.025 14.2 2.0 1.9 1 1 1 2 2 2 0 Putative transposase DNA-binding domain zf-HIT PF04438.11 KLO19474.1 - 2.4 7.8 8.2 4.8 6.9 2.9 2.4 2 0 0 2 2 2 0 HIT zinc finger DUF2602 PF10782.4 KLO19474.1 - 6.2 6.7 7.7 8.9 6.2 0.0 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF2602) Med14 PF08638.6 KLO19475.1 - 1.3e-46 158.3 0.1 2.3e-46 157.4 0.1 1.4 1 0 0 1 1 1 1 Mediator complex subunit MED14 Pkinase PF00069.20 KLO19476.1 - 3e-08 33.1 0.0 8.4e-08 31.6 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain HEAT PF02985.17 KLO19476.1 - 5e-08 32.3 0.0 0.52 10.5 0.0 4.7 4 0 0 4 4 4 3 HEAT repeat Pkinase_Tyr PF07714.12 KLO19476.1 - 0.00012 21.3 0.0 0.00018 20.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase HEAT_EZ PF13513.1 KLO19476.1 - 0.00036 20.9 0.0 0.62 10.6 0.0 3.7 3 0 0 3 3 3 2 HEAT-like repeat Kinase-like PF14531.1 KLO19476.1 - 0.026 13.5 0.0 0.038 12.9 0.0 1.2 1 0 0 1 1 1 0 Kinase-like zf-MYND PF01753.13 KLO19478.1 - 2.5e-09 36.8 7.4 2.5e-09 36.8 5.1 3.5 4 0 0 4 4 4 2 MYND finger zf-Mss51 PF13824.1 KLO19478.1 - 0.012 15.4 2.0 0.012 15.4 1.4 2.7 2 0 0 2 2 2 0 Zinc-finger of mitochondrial splicing suppressor 51 Aa_trans PF01490.13 KLO19479.1 - 3.7e-73 246.3 28.7 4.5e-73 246.0 19.9 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.8 KLO19479.1 - 0.0032 16.3 21.6 0.014 14.2 14.9 2.0 1 1 0 1 1 1 1 Tryptophan/tyrosine permease family GHMP_kinases_N PF00288.21 KLO19480.1 - 4.2e-13 49.1 3.0 1.1e-12 47.7 2.1 1.7 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.8 KLO19480.1 - 8e-08 32.3 0.0 2.3e-07 30.9 0.0 1.8 1 0 0 1 1 1 1 GHMP kinases C terminal Chromo PF00385.19 KLO19482.1 - 3.3e-10 39.4 0.0 7.4e-10 38.3 0.0 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Oxidored_q6 PF01058.17 KLO19483.1 - 2e-22 79.1 0.1 3e-22 78.6 0.1 1.2 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase, 20 Kd subunit HhH-GPD PF00730.20 KLO19484.1 - 4.1e-12 46.3 0.0 2.1e-11 44.0 0.0 2.3 1 1 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein SOG2 PF10428.4 KLO19484.1 - 1.1 7.8 7.7 0.81 8.2 2.0 2.1 2 0 0 2 2 2 0 RAM signalling pathway protein PLA2_B PF01735.13 KLO19485.1 - 1.1e-35 122.7 0.0 4.8e-22 77.7 0.0 2.2 2 0 0 2 2 2 2 Lysophospholipase catalytic domain Toxin_47 PF15527.1 KLO19487.1 - 0.096 12.4 0.0 0.12 12.1 0.0 1.2 1 0 0 1 1 1 0 Putative toxin 47 DUF3397 PF11877.3 KLO19487.1 - 0.15 12.0 2.6 0.19 11.7 1.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3397) F-box-like PF12937.2 KLO19488.1 - 6.8e-09 35.3 0.4 2.3e-08 33.6 0.3 2.0 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KLO19488.1 - 2.9e-08 33.1 0.9 6.1e-08 32.1 0.1 2.0 2 0 0 2 2 2 1 F-box domain DASH_Dad2 PF08654.5 KLO19489.1 - 6.1e-09 35.8 0.0 1.1e-08 35.0 0.0 1.4 1 1 0 1 1 1 1 DASH complex subunit Dad2 SNAP PF14938.1 KLO19489.1 - 0.033 13.3 0.9 0.034 13.2 0.6 1.0 1 0 0 1 1 1 0 Soluble NSF attachment protein, SNAP Hexapep PF00132.19 KLO19490.1 - 3.2e-10 39.0 9.2 3.2e-10 39.0 6.4 2.9 3 0 0 3 3 3 1 Bacterial transferase hexapeptide (six repeats) Mac PF12464.3 KLO19490.1 - 5.4e-10 39.1 1.4 1.1e-09 38.1 1.0 1.5 1 0 0 1 1 1 1 Maltose acetyltransferase Hexapep_2 PF14602.1 KLO19490.1 - 9.8e-06 25.0 7.7 9.8e-06 25.0 5.4 2.6 3 0 0 3 3 3 1 Hexapeptide repeat of succinyl-transferase SSXRD PF09514.5 KLO19490.1 - 0.059 12.6 0.3 0.13 11.6 0.2 1.5 1 0 0 1 1 1 0 SSXRD motif CPSF_A PF03178.10 KLO19491.1 - 5e-95 318.2 0.0 2e-94 316.2 0.0 2.0 2 0 0 2 2 2 1 CPSF A subunit region MMS1_N PF10433.4 KLO19491.1 - 3e-79 266.4 0.0 4.3e-79 265.9 0.0 1.2 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term DDRGK PF09756.4 KLO19492.1 - 0.013 14.9 6.4 0.021 14.2 4.4 1.3 1 0 0 1 1 1 0 DDRGK domain ABC_membrane PF00664.18 KLO19493.1 - 1.7e-51 175.2 31.7 1.3e-27 96.8 8.9 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 KLO19493.1 - 2.5e-49 167.1 0.0 6.1e-28 97.8 0.0 2.6 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 KLO19493.1 - 4.6e-09 36.6 0.0 0.0017 18.3 0.0 4.3 3 1 0 3 3 3 2 AAA domain SMC_N PF02463.14 KLO19493.1 - 6e-09 35.4 0.3 0.017 14.3 0.0 4.0 3 1 0 4 4 4 3 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.18 KLO19493.1 - 8.1e-07 29.0 0.2 0.0087 16.0 0.0 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_29 PF13555.1 KLO19493.1 - 1.8e-06 27.3 0.0 0.021 14.3 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain Miro PF08477.8 KLO19493.1 - 6.7e-06 26.5 0.6 0.033 14.6 0.0 2.8 2 0 0 2 2 2 2 Miro-like protein AAA_16 PF13191.1 KLO19493.1 - 1.7e-05 24.8 2.6 0.0086 16.0 0.2 3.3 3 0 0 3 3 3 1 AAA ATPase domain AAA_25 PF13481.1 KLO19493.1 - 3.7e-05 23.2 0.1 0.062 12.6 0.0 2.9 3 0 0 3 3 3 2 AAA domain AAA_23 PF13476.1 KLO19493.1 - 4.8e-05 23.7 0.7 0.11 12.8 0.0 3.6 3 1 1 4 4 3 1 AAA domain AAA_17 PF13207.1 KLO19493.1 - 0.0003 21.5 0.0 0.33 11.7 0.0 2.7 2 0 0 2 2 2 1 AAA domain FtsK_SpoIIIE PF01580.13 KLO19493.1 - 0.00036 20.0 0.0 0.85 9.0 0.0 2.3 2 0 0 2 2 2 2 FtsK/SpoIIIE family AAA_22 PF13401.1 KLO19493.1 - 0.0004 20.5 0.4 0.5 10.5 0.0 3.2 2 1 0 2 2 2 1 AAA domain DUF258 PF03193.11 KLO19493.1 - 0.00051 19.2 0.1 0.5 9.5 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 Zeta_toxin PF06414.7 KLO19493.1 - 0.00053 19.1 0.3 0.16 11.0 0.0 2.6 3 0 0 3 3 2 1 Zeta toxin Dynamin_N PF00350.18 KLO19493.1 - 0.0036 17.1 6.9 0.15 11.8 0.5 2.9 3 0 0 3 3 3 2 Dynamin family MobB PF03205.9 KLO19493.1 - 0.0067 16.1 0.8 4.1 7.1 0.0 2.8 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_18 PF13238.1 KLO19493.1 - 0.013 15.8 0.0 9 6.6 0.0 2.7 2 0 0 2 2 2 0 AAA domain SbcCD_C PF13558.1 KLO19493.1 - 0.014 15.2 0.1 1.1 9.1 0.1 3.3 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit NB-ARC PF00931.17 KLO19493.1 - 0.018 13.9 0.1 2.6 6.8 0.0 2.3 2 0 0 2 2 2 0 NB-ARC domain AAA_30 PF13604.1 KLO19493.1 - 0.026 14.0 0.3 13 5.3 0.0 2.9 3 0 0 3 3 3 0 AAA domain NACHT PF05729.7 KLO19493.1 - 0.028 14.0 0.6 5.5 6.6 0.0 2.5 2 0 0 2 2 2 0 NACHT domain DUF87 PF01935.12 KLO19493.1 - 0.029 14.1 1.0 1 9.1 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function DUF87 AAA_19 PF13245.1 KLO19493.1 - 0.04 13.6 2.5 3.2 7.5 0.0 4.3 5 0 0 5 5 5 0 Part of AAA domain ATP-synt_ab PF00006.20 KLO19493.1 - 0.041 13.3 0.0 3.6 7.0 0.0 2.4 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain Arch_ATPase PF01637.13 KLO19493.1 - 0.05 13.3 0.0 7.7 6.1 0.0 2.7 2 1 0 2 2 2 0 Archaeal ATPase UPF0079 PF02367.12 KLO19493.1 - 0.06 12.9 0.3 6.8 6.3 0.0 2.6 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 DUF815 PF05673.8 KLO19493.1 - 0.061 12.2 0.5 1.8 7.4 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF815) TrwB_AAD_bind PF10412.4 KLO19493.1 - 0.14 10.7 0.3 5.6 5.4 0.1 2.2 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain cobW PF02492.14 KLO19493.1 - 0.15 11.5 0.6 19 4.6 0.1 2.5 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_10 PF12846.2 KLO19493.1 - 0.18 11.2 1.0 15 4.9 0.0 2.6 2 0 0 2 2 2 0 AAA-like domain AAA_15 PF13175.1 KLO19493.1 - 0.5 9.3 0.0 14 4.5 0.0 2.3 2 0 0 2 2 2 0 AAA ATPase domain ABC_tran PF00005.22 KLO19494.1 - 5.9e-50 169.1 0.0 4.8e-28 98.1 0.0 2.6 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 KLO19494.1 - 2.4e-47 161.6 34.1 2.1e-24 86.4 10.3 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.14 KLO19494.1 - 4.8e-09 35.7 0.2 0.013 14.7 0.0 4.1 3 1 1 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 KLO19494.1 - 5.8e-09 36.3 0.0 0.0063 16.5 0.0 4.4 2 2 0 3 3 3 2 AAA domain MMR_HSR1 PF01926.18 KLO19494.1 - 6.5e-08 32.5 0.3 0.0032 17.4 0.0 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_29 PF13555.1 KLO19494.1 - 7.2e-07 28.6 0.1 0.02 14.4 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_25 PF13481.1 KLO19494.1 - 1.7e-06 27.6 0.1 0.0023 17.3 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.1 KLO19494.1 - 3e-06 27.3 2.8 0.0069 16.3 0.1 3.4 3 0 0 3 3 3 2 AAA ATPase domain DUF258 PF03193.11 KLO19494.1 - 1.6e-05 24.1 0.2 0.11 11.6 0.1 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 Miro PF08477.8 KLO19494.1 - 2.4e-05 24.8 6.7 0.022 15.2 0.0 3.4 4 0 0 4 4 2 2 Miro-like protein AAA_23 PF13476.1 KLO19494.1 - 7.6e-05 23.1 8.2 0.11 12.7 0.0 3.9 4 0 0 4 4 3 2 AAA domain AAA_22 PF13401.1 KLO19494.1 - 0.00022 21.3 0.8 0.79 9.8 0.0 3.4 3 1 0 3 3 2 2 AAA domain AAA_17 PF13207.1 KLO19494.1 - 0.00062 20.5 0.0 0.74 10.6 0.0 2.8 2 0 0 2 2 2 1 AAA domain FtsK_SpoIIIE PF01580.13 KLO19494.1 - 0.0013 18.2 0.0 0.82 9.0 0.0 2.4 2 0 0 2 2 2 1 FtsK/SpoIIIE family NACHT PF05729.7 KLO19494.1 - 0.0017 18.0 0.5 0.46 10.1 0.0 2.6 2 0 0 2 2 2 1 NACHT domain Zeta_toxin PF06414.7 KLO19494.1 - 0.0018 17.4 0.4 0.33 10.0 0.0 2.4 2 0 0 2 2 2 1 Zeta toxin MobB PF03205.9 KLO19494.1 - 0.0036 17.0 1.1 2.1 8.0 0.0 2.7 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B SbcCD_C PF13558.1 KLO19494.1 - 0.0068 16.3 0.1 0.94 9.4 0.1 3.3 2 1 0 2 2 2 1 Putative exonuclease SbcCD, C subunit UPF0079 PF02367.12 KLO19494.1 - 0.012 15.2 0.3 1.4 8.5 0.0 2.5 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 ArgK PF03308.11 KLO19494.1 - 0.014 14.2 0.1 1.9 7.1 0.0 2.5 2 0 0 2 2 2 0 ArgK protein AAA_18 PF13238.1 KLO19494.1 - 0.016 15.5 1.3 9.9 6.4 0.0 3.2 3 0 0 3 3 3 0 AAA domain ATP-synt_ab PF00006.20 KLO19494.1 - 0.017 14.6 0.0 1.3 8.4 0.0 2.5 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain cobW PF02492.14 KLO19494.1 - 0.024 14.0 0.5 6.3 6.1 0.0 2.6 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain NB-ARC PF00931.17 KLO19494.1 - 0.025 13.4 0.1 6.4 5.5 0.0 2.4 2 0 0 2 2 2 0 NB-ARC domain PduV-EutP PF10662.4 KLO19494.1 - 0.032 13.7 0.6 8.7 5.8 0.0 2.8 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation DUF815 PF05673.8 KLO19494.1 - 0.045 12.6 0.6 1.6 7.5 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) Dynamin_N PF00350.18 KLO19494.1 - 0.061 13.1 11.9 0.24 11.1 0.5 3.6 4 0 0 4 4 4 0 Dynamin family Arch_ATPase PF01637.13 KLO19494.1 - 0.11 12.1 7.7 1.5 8.4 0.0 3.9 4 1 0 4 4 3 0 Archaeal ATPase AAA_10 PF12846.2 KLO19494.1 - 0.22 10.9 3.1 8 5.7 0.5 2.7 2 0 0 2 2 2 0 AAA-like domain Cation_efflux PF01545.16 KLO19495.1 - 1.3e-07 30.9 9.4 2.8e-07 29.8 6.5 1.5 1 1 0 1 1 1 1 Cation efflux family zf-MYND PF01753.13 KLO19496.1 - 3.5e-06 26.7 10.4 7.7e-06 25.6 7.2 1.6 1 0 0 1 1 1 1 MYND finger zf-MYND PF01753.13 KLO19497.1 - 2.7e-05 23.9 11.7 7.4e-05 22.5 8.1 1.8 1 0 0 1 1 1 1 MYND finger VanZ PF04892.7 KLO19498.1 - 2.9e-08 33.7 4.2 2.5e-07 30.7 2.9 2.0 1 1 0 1 1 1 1 VanZ like family DUF2339 PF10101.4 KLO19498.1 - 0.0038 15.5 1.3 0.0051 15.1 0.9 1.0 1 0 0 1 1 1 1 Predicted membrane protein (DUF2339) TcpE PF12648.2 KLO19498.1 - 0.024 14.7 1.6 0.024 14.7 1.1 1.6 1 1 1 2 2 2 0 TcpE family FUSC-like PF12805.2 KLO19498.1 - 0.26 10.1 1.8 0.18 10.7 0.1 1.5 2 0 0 2 2 2 0 FUSC-like inner membrane protein yccS GtrA PF04138.9 KLO19498.1 - 1 9.3 5.6 1.1 9.1 0.0 2.2 1 1 0 2 2 2 0 GtrA-like protein 7TMR-DISM_7TM PF07695.6 KLO19498.1 - 1.4 8.5 8.8 0.99 9.0 4.6 1.5 1 1 0 1 1 1 0 7TM diverse intracellular signalling Fig1 PF12351.3 KLO19498.1 - 4.4 7.1 6.0 30 4.4 2.1 2.1 2 0 0 2 2 2 0 Ca2+ regulator and membrane fusion protein Fig1 Prominin PF05478.6 KLO19499.1 - 0.28 8.6 0.6 1.6 6.1 0.2 2.1 2 0 0 2 2 2 0 Prominin IPPT PF01715.12 KLO19500.1 - 4.5e-49 166.7 0.1 7.9e-27 93.8 0.0 3.0 1 1 1 2 2 2 2 IPP transferase AAA_18 PF13238.1 KLO19500.1 - 1.1e-07 32.1 0.1 0.0067 16.7 0.0 2.9 3 0 0 3 3 3 2 AAA domain KTI12 PF08433.5 KLO19500.1 - 0.02 14.1 0.4 0.074 12.2 0.0 2.0 2 0 0 2 2 2 0 Chromatin associated protein KTI12 AAA_17 PF13207.1 KLO19500.1 - 0.032 15.0 0.1 0.093 13.5 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.1 KLO19500.1 - 0.033 14.0 0.1 4.7 7.0 0.1 2.8 2 1 0 2 2 2 0 AAA domain Tim17 PF02466.14 KLO19502.1 - 2.6e-31 108.2 4.4 3.3e-31 107.9 3.0 1.1 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family BTB PF00651.26 KLO19503.1 - 0.014 15.3 0.0 0.028 14.4 0.0 1.4 1 0 0 1 1 1 0 BTB/POZ domain Form_Nir_trans PF01226.12 KLO19506.1 - 1.8e-69 233.4 14.4 2.1e-69 233.1 10.0 1.0 1 0 0 1 1 1 1 Formate/nitrite transporter PI3_PI4_kinase PF00454.22 KLO19507.1 - 1.4e-36 126.1 0.0 2.6e-36 125.2 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase RRM_6 PF14259.1 KLO19508.1 - 2.1e-11 43.6 0.0 0.00023 21.0 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 KLO19508.1 - 2e-10 40.1 0.1 0.00019 20.9 0.0 2.8 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KLO19508.1 - 9e-07 28.6 0.0 7.5e-05 22.4 0.0 2.6 2 1 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Pkinase PF00069.20 KLO19509.1 - 2e-46 158.2 0.0 9.9e-35 119.9 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 KLO19509.1 - 1.6e-16 60.1 0.0 8.4e-12 44.7 0.0 2.3 2 1 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 KLO19509.1 - 0.00022 20.2 0.0 0.00061 18.8 0.0 1.6 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 KLO19509.1 - 0.0044 16.7 0.3 0.021 14.5 0.0 2.0 2 0 0 2 2 2 1 Phosphotransferase enzyme family Glyco_transf_90 PF05686.7 KLO19511.1 - 2.1e-21 76.0 0.9 4e-21 75.1 0.1 1.8 2 0 0 2 2 2 1 Glycosyl transferase family 90 Pkinase PF00069.20 KLO19512.1 - 1.1e-17 64.0 0.0 2.8e-17 62.7 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KLO19512.1 - 2e-16 59.8 0.0 1.2e-15 57.2 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Hydrophobin PF01185.13 KLO19514.1 - 1.1e-12 48.2 4.7 1.3e-12 47.9 3.2 1.1 1 0 0 1 1 1 1 Fungal hydrophobin YbgS PF13985.1 KLO19514.1 - 0.078 12.8 0.7 0.088 12.7 0.5 1.2 1 0 0 1 1 1 0 YbgS-like protein Hydrophobin PF01185.13 KLO19516.1 - 1.8e-13 50.7 6.1 2.2e-13 50.4 4.2 1.1 1 0 0 1 1 1 1 Fungal hydrophobin PepSY_2 PF13670.1 KLO19516.1 - 0.1 12.4 0.8 0.15 12.0 0.6 1.2 1 0 0 1 1 1 0 Peptidase propeptide and YPEB domain Diacid_rec PF05651.8 KLO19516.1 - 0.13 11.6 0.1 0.13 11.6 0.0 1.3 1 0 0 1 1 1 0 Putative sugar diacid recognition Hydrophobin PF01185.13 KLO19517.1 - 9e-14 51.6 5.3 1.1e-13 51.4 3.7 1.1 1 0 0 1 1 1 1 Fungal hydrophobin Diacid_rec PF05651.8 KLO19517.1 - 0.15 11.4 0.0 0.16 11.3 0.0 1.2 1 0 0 1 1 1 0 Putative sugar diacid recognition PepSY_2 PF13670.1 KLO19517.1 - 0.15 11.9 1.3 0.2 11.5 0.9 1.2 1 0 0 1 1 1 0 Peptidase propeptide and YPEB domain Ecm33 PF12454.3 KLO19517.1 - 1.4 8.8 6.4 0.23 11.3 1.2 2.0 2 0 0 2 2 2 0 GPI-anchored cell wall organization protein Hydrophobin PF01185.13 KLO19518.1 - 1.9e-12 47.4 4.0 2.3e-12 47.1 2.8 1.1 1 0 0 1 1 1 1 Fungal hydrophobin RNase_P_pop3 PF08228.6 KLO19519.1 - 4.7e-16 59.0 0.3 2e-10 40.7 0.0 3.0 2 1 0 2 2 2 2 RNase P subunit Pop3 PAC2 PF09754.4 KLO19520.1 - 1.9e-23 83.4 0.0 2.3e-23 83.1 0.0 1.1 1 0 0 1 1 1 1 PAC2 family SLAC1 PF03595.12 KLO19523.1 - 3e-73 246.3 53.2 3.4e-73 246.1 36.9 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel Inhibitor_I9 PF05922.11 KLO19524.1 - 0.0012 19.3 0.2 0.0012 19.3 0.1 1.5 2 0 0 2 2 2 1 Peptidase inhibitor I9 DUF1351 PF07083.6 KLO19524.1 - 0.049 13.2 3.2 0.19 11.3 1.0 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1351) Viral_Hsp90 PF03225.9 KLO19525.1 - 0.063 11.5 0.1 0.069 11.4 0.0 1.0 1 0 0 1 1 1 0 Viral heat shock protein Hsp90 homologue NACHT PF05729.7 KLO19527.1 - 5.1e-22 78.3 0.5 8.3e-08 32.0 0.0 4.9 4 2 0 4 4 4 3 NACHT domain AAA_16 PF13191.1 KLO19527.1 - 2.5e-18 66.7 0.1 2.1e-06 27.8 0.0 3.9 3 0 0 3 3 3 3 AAA ATPase domain AAA_22 PF13401.1 KLO19527.1 - 2.8e-13 50.1 0.0 0.0001 22.4 0.0 4.2 3 1 0 3 3 3 3 AAA domain NB-ARC PF00931.17 KLO19527.1 - 2.4e-11 43.0 0.0 0.00037 19.4 0.0 3.8 3 1 0 3 3 3 2 NB-ARC domain AAA_19 PF13245.1 KLO19527.1 - 9.8e-11 41.2 0.0 0.029 14.1 0.0 4.1 3 0 0 3 3 3 3 Part of AAA domain RNA_helicase PF00910.17 KLO19527.1 - 9.2e-09 35.4 0.0 0.18 12.0 0.0 4.1 3 1 0 3 3 3 2 RNA helicase Zeta_toxin PF06414.7 KLO19527.1 - 9.4e-08 31.3 0.0 0.12 11.5 0.0 3.5 3 0 0 3 3 3 2 Zeta toxin AAA PF00004.24 KLO19527.1 - 1.1e-07 32.1 0.0 0.095 12.8 0.0 4.4 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) KaiC PF06745.8 KLO19527.1 - 2.8e-07 29.9 0.0 0.016 14.3 0.0 3.7 3 0 0 3 3 3 1 KaiC AAA_11 PF13086.1 KLO19527.1 - 5e-07 29.5 0.0 0.66 9.5 0.0 3.4 3 0 0 3 3 3 2 AAA domain APS_kinase PF01583.15 KLO19527.1 - 1.4e-06 28.0 0.3 0.21 11.2 0.0 4.0 4 0 0 4 4 3 2 Adenylylsulphate kinase AAA_14 PF13173.1 KLO19527.1 - 2.4e-06 27.4 0.0 1.5 8.6 0.0 4.8 4 0 0 4 4 4 1 AAA domain DUF2075 PF09848.4 KLO19527.1 - 2.8e-06 26.5 0.0 0.043 12.7 0.0 3.3 3 0 0 3 3 3 1 Uncharacterized conserved protein (DUF2075) cobW PF02492.14 KLO19527.1 - 5.1e-06 26.0 0.0 2.2 7.6 0.0 3.7 3 0 0 3 3 3 2 CobW/HypB/UreG, nucleotide-binding domain Arch_ATPase PF01637.13 KLO19527.1 - 8.5e-06 25.6 0.0 0.23 11.1 0.0 3.7 3 0 0 3 3 3 1 Archaeal ATPase AAA_17 PF13207.1 KLO19527.1 - 5.2e-05 24.0 0.4 9.4 7.0 0.0 5.0 4 0 0 4 4 3 0 AAA domain AAA_25 PF13481.1 KLO19527.1 - 8.2e-05 22.0 0.0 0.5 9.7 0.0 3.7 3 0 0 3 3 3 1 AAA domain NTPase_1 PF03266.10 KLO19527.1 - 0.00016 21.4 0.0 4 7.1 0.0 3.5 3 0 0 3 3 3 0 NTPase Viral_helicase1 PF01443.13 KLO19527.1 - 0.0002 20.9 0.0 0.68 9.4 0.0 3.4 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase AAA_33 PF13671.1 KLO19527.1 - 0.00021 21.1 0.1 4.9 7.0 0.0 4.3 4 0 0 4 4 4 0 AAA domain AAA_18 PF13238.1 KLO19527.1 - 0.00027 21.2 0.0 5.8 7.2 0.0 3.9 3 0 0 3 3 3 0 AAA domain Parvo_NS1 PF01057.12 KLO19527.1 - 0.00074 18.4 0.1 0.66 8.7 0.0 2.4 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 IstB_IS21 PF01695.12 KLO19527.1 - 0.00095 18.6 0.1 1.3 8.4 0.0 3.2 3 0 0 3 3 3 1 IstB-like ATP binding protein UPF0079 PF02367.12 KLO19527.1 - 0.0011 18.5 0.0 7.4 6.2 0.0 3.5 3 0 0 3 3 3 0 Uncharacterised P-loop hydrolase UPF0079 PhoH PF02562.11 KLO19527.1 - 0.0045 16.2 0.0 3.7 6.7 0.0 2.7 3 0 0 3 3 2 1 PhoH-like protein ResIII PF04851.10 KLO19527.1 - 0.0046 16.8 0.0 2.9 7.6 0.0 3.2 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit Elong_Iki1 PF10483.4 KLO19527.1 - 0.0087 15.4 0.0 0.043 13.1 0.0 2.0 2 0 0 2 2 2 1 Elongator subunit Iki1 PIF1 PF05970.9 KLO19527.1 - 0.012 14.5 0.0 8.7 5.1 0.0 3.2 3 0 0 3 3 3 0 PIF1-like helicase AAA_30 PF13604.1 KLO19527.1 - 0.022 14.3 0.0 10 5.6 0.0 3.3 3 0 0 3 3 3 0 AAA domain KAP_NTPase PF07693.9 KLO19527.1 - 0.031 13.2 6.9 0.95 8.3 0.1 4.9 5 1 0 5 5 5 0 KAP family P-loop domain Mg_chelatase PF01078.16 KLO19527.1 - 0.053 12.6 0.0 7.6 5.6 0.0 2.7 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI TIP49 PF06068.8 KLO19527.1 - 0.054 12.1 0.0 18 3.9 0.0 3.0 3 0 0 3 3 3 0 TIP49 C-terminus ArgK PF03308.11 KLO19527.1 - 0.057 12.2 0.0 3.2 6.4 0.0 3.0 3 0 0 3 3 3 0 ArgK protein Sigma54_activat PF00158.21 KLO19527.1 - 0.073 12.5 0.0 11 5.4 0.0 2.7 3 0 0 3 3 2 0 Sigma-54 interaction domain FtsK_SpoIIIE PF01580.13 KLO19527.1 - 0.076 12.4 0.1 62 2.9 0.0 3.5 3 0 0 3 3 3 0 FtsK/SpoIIIE family AAA_28 PF13521.1 KLO19527.1 - 0.12 12.3 2.1 5.5 6.9 0.0 3.1 3 0 0 3 3 2 0 AAA domain AAA_24 PF13479.1 KLO19527.1 - 0.7 9.4 3.1 31 4.0 0.1 3.2 3 0 0 3 3 3 0 AAA domain LETM1 PF07766.8 KLO19529.1 - 4.9e-23 81.5 0.9 8.8e-12 44.6 0.0 2.1 1 1 1 2 2 2 2 LETM1-like protein TSP_C PF05735.7 KLO19531.1 - 0.16 11.5 0.1 3.2 7.2 0.0 2.0 2 0 0 2 2 2 0 Thrombospondin C-terminal region TPR_11 PF13414.1 KLO19533.1 - 7.4e-56 185.7 26.5 1.9e-10 40.2 0.1 14.1 9 4 7 16 16 16 13 TPR repeat TPR_2 PF07719.12 KLO19533.1 - 2.2e-38 127.1 23.0 0.00029 20.5 0.1 18.3 19 0 0 19 19 18 7 Tetratricopeptide repeat TPR_16 PF13432.1 KLO19533.1 - 3e-36 123.3 36.1 7.3e-08 32.8 0.4 12.8 9 3 4 14 14 13 7 Tetratricopeptide repeat TPR_12 PF13424.1 KLO19533.1 - 7.1e-30 102.7 33.6 4.4e-06 26.5 0.9 13.0 8 3 6 14 14 14 11 Tetratricopeptide repeat TPR_14 PF13428.1 KLO19533.1 - 3.1e-28 95.6 43.1 0.027 15.0 0.1 19.8 11 7 11 22 22 21 9 Tetratricopeptide repeat TPR_1 PF00515.23 KLO19533.1 - 1.6e-27 93.9 20.9 0.0062 16.0 0.0 14.1 15 0 0 15 15 15 6 Tetratricopeptide repeat TPR_19 PF14559.1 KLO19533.1 - 4.5e-25 87.7 39.8 2.9e-07 30.7 0.1 13.7 10 4 6 17 17 16 8 Tetratricopeptide repeat TPR_17 PF13431.1 KLO19533.1 - 2.9e-23 80.0 23.7 3.5e-05 23.6 0.2 15.7 19 0 0 19 19 16 5 Tetratricopeptide repeat TPR_8 PF13181.1 KLO19533.1 - 9.4e-23 78.2 27.7 0.0058 16.3 0.3 15.8 18 0 0 18 18 17 6 Tetratricopeptide repeat Apc3 PF12895.2 KLO19533.1 - 9e-16 57.7 15.3 7.8e-07 29.1 0.0 9.4 7 3 4 11 11 9 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.1 KLO19533.1 - 5.3e-11 41.4 25.4 0.18 11.6 0.0 12.2 15 0 0 15 15 11 3 Tetratricopeptide repeat TPR_9 PF13371.1 KLO19533.1 - 4.5e-10 39.2 18.4 0.0011 18.8 0.0 9.6 9 3 2 11 11 11 4 Tetratricopeptide repeat TPR_6 PF13174.1 KLO19533.1 - 7.5e-08 32.3 24.6 0.28 11.7 0.0 14.2 17 0 0 17 17 16 1 Tetratricopeptide repeat DUF3808 PF10300.4 KLO19533.1 - 7.6e-06 24.7 0.3 0.14 10.6 0.0 3.3 3 0 0 3 3 3 2 Protein of unknown function (DUF3808) TPR_20 PF14561.1 KLO19533.1 - 0.0048 16.9 16.8 0.15 12.1 0.1 7.1 7 1 1 8 8 7 2 Tetratricopeptide repeat Clathrin PF00637.15 KLO19533.1 - 0.017 14.7 0.8 12 5.4 0.0 4.0 4 0 0 4 4 4 0 Region in Clathrin and VPS ChAPs PF09295.5 KLO19533.1 - 0.22 10.2 2.3 19 3.9 0.0 3.7 4 0 0 4 4 4 0 ChAPs (Chs5p-Arf1p-binding proteins) F-box PF00646.28 KLO19534.1 - 1.1e-05 24.9 0.5 2.6e-05 23.7 0.3 1.6 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 KLO19534.1 - 0.0007 19.2 0.3 0.0018 17.9 0.2 1.7 1 0 0 1 1 1 1 F-box-like DUF3094 PF11293.3 KLO19534.1 - 0.066 12.6 0.9 1.6 8.2 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF3094) YvbH_ext PF11724.3 KLO19534.1 - 0.12 12.0 0.0 0.29 10.8 0.0 1.6 1 0 0 1 1 1 0 YvbH-like oligomerisation region Lipase_GDSL_2 PF13472.1 KLO19535.1 - 8.8e-13 48.7 0.8 1.7e-12 47.8 0.5 1.4 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 KLO19535.1 - 3.9e-12 46.5 0.3 3.3e-11 43.4 0.2 2.0 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase DSPc PF00782.15 KLO19537.1 - 0.00018 21.1 0.0 0.00041 19.9 0.0 1.5 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain CDKN3 PF05706.7 KLO19537.1 - 0.0046 16.4 0.1 0.0081 15.6 0.1 1.3 1 0 0 1 1 1 1 Cyclin-dependent kinase inhibitor 3 (CDKN3) Y_phosphatase PF00102.22 KLO19537.1 - 0.05 12.9 0.3 0.14 11.5 0.2 1.7 1 1 0 1 1 1 0 Protein-tyrosine phosphatase DUF442 PF04273.8 KLO19537.1 - 0.095 12.5 0.0 0.25 11.1 0.0 1.7 1 0 0 1 1 1 0 Putative phosphatase (DUF442) PTPlike_phytase PF14566.1 KLO19537.1 - 0.11 12.4 0.0 0.24 11.4 0.0 1.5 1 0 0 1 1 1 0 Inositol hexakisphosphate Y_phosphatase3 PF13350.1 KLO19537.1 - 0.11 12.6 0.2 0.29 11.3 0.1 1.6 1 0 0 1 1 1 0 Tyrosine phosphatase family Chitin_synth_2 PF03142.10 KLO19538.1 - 6.9e-250 829.9 0.0 9.1e-250 829.5 0.0 1.1 1 0 0 1 1 1 1 Chitin synthase Glyco_trans_2_3 PF13632.1 KLO19538.1 - 2.2e-18 66.6 4.3 2.2e-18 66.6 3.0 2.6 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 KLO19538.1 - 1.5e-15 57.6 0.0 2.3e-14 53.7 0.0 2.2 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Cyt-b5 PF00173.23 KLO19538.1 - 5.1e-07 29.3 0.0 1.8e-05 24.4 0.0 2.6 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain Glyco_transf_21 PF13506.1 KLO19538.1 - 9.9e-06 24.9 0.1 0.0015 17.8 0.0 2.3 2 0 0 2 2 2 2 Glycosyl transferase family 21 Glycos_transf_2 PF00535.21 KLO19538.1 - 0.0074 15.9 0.1 0.2 11.3 0.0 2.8 3 0 0 3 3 3 1 Glycosyl transferase family 2 F-box PF00646.28 KLO19539.1 - 1.6e-05 24.4 0.2 3.1e-05 23.4 0.1 1.5 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 KLO19539.1 - 0.002 17.8 0.1 0.0039 16.8 0.0 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KLO19540.1 - 0.00089 18.8 0.5 0.0023 17.5 0.3 1.7 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 KLO19540.1 - 0.023 14.3 0.4 0.059 13.0 0.3 1.7 1 0 0 1 1 1 0 F-box-like F-box-like PF12937.2 KLO19541.1 - 0.027 14.2 2.2 0.2 11.3 1.5 2.3 1 1 0 1 1 1 0 F-box-like WD40 PF00400.27 KLO19542.1 - 0.00089 19.0 1.8 0.0028 17.4 0.3 2.7 3 0 0 3 3 3 1 WD domain, G-beta repeat MFS_1 PF07690.11 KLO19543.1 - 6.8e-51 173.0 44.4 3.1e-50 170.8 30.7 2.0 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.8 KLO19543.1 - 2e-19 69.2 20.5 2.6e-19 68.8 14.2 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 KLO19543.1 - 1e-11 44.0 10.0 1e-11 44.0 6.9 3.2 2 1 1 3 3 3 2 Sugar (and other) transporter HlyIII PF03006.15 KLO19543.1 - 0.00079 18.9 2.4 0.00079 18.9 1.6 2.6 1 1 1 2 2 2 1 Haemolysin-III related ATG22 PF11700.3 KLO19543.1 - 0.00079 18.0 17.8 0.0027 16.2 0.6 4.0 2 2 2 4 4 4 2 Vacuole effluxer Atg22 like DUF3185 PF11381.3 KLO19543.1 - 0.0067 16.1 2.3 0.0067 16.1 1.6 2.9 2 1 0 2 2 2 1 Protein of unknown function (DUF3185) DUF4131 PF13567.1 KLO19543.1 - 3.3 7.0 24.2 0.075 12.4 2.2 4.7 3 1 2 5 5 5 0 Domain of unknown function (DUF4131) Ten1_2 PF15490.1 KLO19544.1 - 2e-05 24.1 0.0 2.5e-05 23.8 0.0 1.1 1 0 0 1 1 1 1 Telomere-capping, CST complex subunit Ten1 PF12658.2 KLO19544.1 - 0.12 12.1 0.0 0.27 10.9 0.0 1.8 1 1 0 1 1 1 0 Telomere capping, CST complex subunit zf-MYND PF01753.13 KLO19545.1 - 1.7e-10 40.6 14.1 1.7e-10 40.6 9.8 1.9 2 0 0 2 2 2 1 MYND finger zf-Mss51 PF13824.1 KLO19545.1 - 1.4 8.8 12.2 0.1 12.4 4.9 1.8 2 0 0 2 2 2 0 Zinc-finger of mitochondrial splicing suppressor 51 F-box-like PF12937.2 KLO19546.1 - 0.013 15.1 0.5 0.05 13.3 0.3 2.1 1 1 0 1 1 1 0 F-box-like F-box PF00646.28 KLO19547.1 - 0.0001 21.8 1.0 0.00029 20.4 0.3 2.1 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.2 KLO19547.1 - 0.0031 17.1 0.2 0.0094 15.6 0.2 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KLO19548.1 - 0.00051 19.6 0.2 0.0011 18.5 0.1 1.6 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 KLO19548.1 - 0.0011 18.6 0.2 0.0023 17.6 0.1 1.5 1 0 0 1 1 1 1 F-box-like Adaptin_binding PF10199.4 KLO19548.1 - 0.27 11.5 7.7 0.28 11.4 4.6 1.6 2 0 0 2 2 2 0 Alpha and gamma adaptin binding protein p34 CDC45 PF02724.9 KLO19548.1 - 3.4 5.5 12.5 4.8 5.0 8.6 1.1 1 0 0 1 1 1 0 CDC45-like protein DivIC PF04977.10 KLO19550.1 - 0.28 10.7 3.0 12 5.5 0.7 2.3 1 1 0 2 2 2 0 Septum formation initiator Pneumo_phosprot PF02478.11 KLO19550.1 - 0.5 9.8 6.8 1 8.8 0.1 2.3 2 0 0 2 2 2 0 Pneumovirus phosphoprotein Seryl_tRNA_N PF02403.17 KLO19550.1 - 1.2 9.1 4.6 2.5 8.1 3.2 1.4 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain bZIP_2 PF07716.10 KLO19550.1 - 3.1 7.6 5.5 15 5.4 0.6 2.5 2 0 0 2 2 2 0 Basic region leucine zipper F-box PF00646.28 KLO19551.1 - 5.8e-07 29.0 0.3 2.5e-06 27.0 0.2 2.2 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 KLO19551.1 - 0.0016 18.1 1.9 0.0016 18.0 0.2 1.9 2 0 0 2 2 2 1 F-box-like RRM_DME PF15628.1 KLO19551.1 - 0.092 12.4 0.0 0.21 11.3 0.0 1.6 1 0 0 1 1 1 0 RRM in Demeter Peptidase_C1_2 PF03051.10 KLO19552.1 - 1.4e-149 498.3 0.2 1.6e-149 498.1 0.1 1.0 1 0 0 1 1 1 1 Peptidase C1-like family Peptidase_C1 PF00112.18 KLO19552.1 - 1.1e-07 31.9 0.0 0.0059 16.5 0.0 2.6 3 0 0 3 3 3 2 Papain family cysteine protease zf-C4_ClpX PF06689.8 KLO19553.1 - 0.03 13.8 0.1 0.15 11.5 0.0 2.1 2 0 0 2 2 2 0 ClpX C4-type zinc finger 7TM_GPCR_Srd PF10317.4 KLO19553.1 - 0.1 11.5 0.0 0.18 10.7 0.0 1.3 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srd Gelsolin PF00626.17 KLO19554.1 - 0.0016 18.0 0.3 0.0074 15.9 0.0 2.2 2 0 0 2 2 2 1 Gelsolin repeat Med27 PF11571.3 KLO19555.1 - 1.1e-10 41.4 0.0 2.3e-10 40.4 0.0 1.5 1 0 0 1 1 1 1 Mediator complex subunit 27 RasGAP PF00616.14 KLO19555.1 - 0.19 11.3 0.0 0.19 11.3 0.0 2.1 2 1 0 2 2 2 0 GTPase-activator protein for Ras-like GTPase DOCK-C2 PF14429.1 KLO19558.1 - 5.6e-39 133.6 0.0 1.3e-38 132.5 0.0 1.7 1 0 0 1 1 1 1 C2 domain in Dock180 and Zizimin proteins Ded_cyto PF06920.8 KLO19558.1 - 3.3e-37 127.5 0.2 6.9e-37 126.4 0.1 1.6 1 0 0 1 1 1 1 Dedicator of cytokinesis WD40 PF00400.27 KLO19559.1 - 1.1e-37 126.5 6.8 2e-09 36.9 0.0 6.7 7 0 0 7 7 7 6 WD domain, G-beta repeat BBS2_Mid PF14783.1 KLO19559.1 - 0.011 15.5 0.1 17 5.2 0.0 4.2 4 2 0 4 4 4 0 Ciliary BBSome complex subunit 2, middle region PQQ PF01011.16 KLO19559.1 - 0.05 13.1 0.0 9.6 5.9 0.0 2.9 2 0 0 2 2 2 0 PQQ enzyme repeat Nup160 PF11715.3 KLO19559.1 - 0.4 8.7 2.4 4.1 5.4 0.3 3.3 3 1 0 3 3 3 0 Nucleoporin Nup120/160 LSM PF01423.17 KLO19560.1 - 3.3e-14 52.1 0.3 4.5e-14 51.7 0.2 1.2 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 KLO19560.1 - 0.0007 19.4 0.1 0.00086 19.1 0.0 1.1 1 0 0 1 1 1 1 Ataxin 2 SM domain Peptidase_C1_2 PF03051.10 KLO19561.1 - 1.6e-156 521.2 0.1 1.8e-156 521.0 0.0 1.0 1 0 0 1 1 1 1 Peptidase C1-like family Peptidase_C1 PF00112.18 KLO19561.1 - 9e-08 32.2 0.0 0.0022 17.9 0.0 2.6 2 0 0 2 2 2 2 Papain family cysteine protease Phage_portal_2 PF05136.8 KLO19561.1 - 0.059 11.8 0.0 0.091 11.2 0.0 1.2 1 0 0 1 1 1 0 Phage portal protein, lambda family AA_permease_2 PF13520.1 KLO19562.1 - 0.0091 14.5 0.5 0.011 14.3 0.4 1.2 1 0 0 1 1 1 1 Amino acid permease Macoilin PF09726.4 KLO19563.1 - 0.00018 19.9 6.2 0.00021 19.7 4.3 1.1 1 0 0 1 1 1 1 Transmembrane protein DUF3552 PF12072.3 KLO19563.1 - 0.0026 17.0 8.8 0.004 16.3 6.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3552) ADIP PF11559.3 KLO19563.1 - 0.013 15.4 6.7 0.013 15.4 4.6 1.5 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding CENP-Q PF13094.1 KLO19563.1 - 0.11 12.5 9.4 0.19 11.7 6.5 1.4 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit GAS PF13851.1 KLO19563.1 - 0.14 11.3 6.5 0.21 10.7 4.5 1.2 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding IncA PF04156.9 KLO19563.1 - 0.18 11.3 6.6 0.27 10.8 4.6 1.3 1 0 0 1 1 1 0 IncA protein FliJ PF02050.11 KLO19563.1 - 0.38 10.8 14.1 0.066 13.2 7.3 1.6 2 0 0 2 2 2 0 Flagellar FliJ protein OmpH PF03938.9 KLO19563.1 - 1.1 9.2 5.9 1.7 8.5 4.1 1.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) APG6 PF04111.7 KLO19563.1 - 3.6 6.5 6.9 5.7 5.8 4.8 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF4230 PF14014.1 KLO19563.1 - 9.8 6.0 7.5 9 6.1 2.7 2.3 2 1 1 3 3 3 0 Protein of unknown function (DUF4230) Pkinase PF00069.20 KLO19564.1 - 8.2e-68 228.3 0.0 1.6e-67 227.3 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KLO19564.1 - 2.8e-38 131.4 0.0 3.7e-37 127.7 0.0 2.3 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KLO19564.1 - 7.3e-05 21.8 0.0 0.00016 20.7 0.0 1.6 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 KLO19564.1 - 0.00034 20.4 3.0 0.19 11.4 0.0 3.4 2 1 1 3 3 3 2 Phosphotransferase enzyme family Gp58 PF07902.6 KLO19564.1 - 0.0042 15.3 0.7 0.0062 14.8 0.5 1.2 1 0 0 1 1 1 1 gp58-like protein AAA_13 PF13166.1 KLO19564.1 - 0.28 9.5 13.7 0.41 9.0 9.5 1.2 1 0 0 1 1 1 0 AAA domain Spc7 PF08317.6 KLO19564.1 - 5.5 5.5 23.0 1.8 7.1 4.9 2.2 1 1 1 2 2 2 0 Spc7 kinetochore protein DUF4231 PF14015.1 KLO19566.1 - 1.5 8.8 6.0 0.17 11.8 0.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4231) F-box PF00646.28 KLO19567.1 - 5.6e-05 22.6 0.3 0.00016 21.2 0.2 1.8 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 KLO19567.1 - 0.0029 17.2 0.2 0.008 15.8 0.1 1.7 1 0 0 1 1 1 1 F-box-like LRRC37AB_C PF14914.1 KLO19567.1 - 0.03 13.7 0.1 0.057 12.8 0.1 1.4 1 0 0 1 1 1 0 LRRC37A/B like protein 1 C-terminal domain zinc_ribbon_6 PF14599.1 KLO19567.1 - 0.22 11.3 1.9 1.2 8.9 0.2 2.5 2 0 0 2 2 2 0 Zinc-ribbon Ribosomal_S7 PF00177.16 KLO19568.1 - 6.6e-41 139.3 3.6 7.9e-41 139.0 2.5 1.1 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e Hemopexin PF00045.14 KLO19569.1 - 0.00093 18.8 1.6 3.4 7.4 0.0 4.1 4 0 0 4 4 4 2 Hemopexin PS_pyruv_trans PF04230.8 KLO19570.1 - 0.032 13.9 0.1 0.87 9.2 0.0 2.0 2 0 0 2 2 2 0 Polysaccharide pyruvyl transferase DUF1764 PF08576.5 KLO19570.1 - 0.11 13.2 0.1 0.37 11.5 0.0 1.9 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF1764) DUF4641 PF15483.1 KLO19575.1 - 0.048 12.3 0.1 0.061 12.0 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4641) FAD_binding_6 PF00970.19 KLO19577.1 - 0.11 12.5 0.0 0.34 11.0 0.0 1.8 1 0 0 1 1 1 0 Oxidoreductase FAD-binding domain Zn_clus PF00172.13 KLO19579.1 - 0.00018 21.3 7.3 0.00036 20.3 5.1 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain EF-hand_6 PF13405.1 KLO19581.1 - 9.9e-11 40.5 0.1 6.7e-05 22.4 0.0 3.1 4 0 0 4 4 4 2 EF-hand domain EF-hand_7 PF13499.1 KLO19581.1 - 1.2e-10 41.3 0.0 3.5e-06 27.0 0.0 2.3 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.27 KLO19581.1 - 2.7e-10 38.7 0.8 0.00017 20.6 0.0 3.5 4 0 0 4 4 4 2 EF hand EF-hand_9 PF14658.1 KLO19581.1 - 1.9e-07 30.8 0.0 0.0097 15.8 0.0 2.5 2 1 0 2 2 2 2 EF-hand domain EF-hand_8 PF13833.1 KLO19581.1 - 2.9e-05 23.5 0.1 0.11 12.0 0.1 3.3 3 1 1 4 4 4 2 EF-hand domain pair UPF0154 PF03672.8 KLO19581.1 - 0.003 17.1 0.0 0.057 13.0 0.0 2.4 2 1 0 2 2 2 1 Uncharacterised protein family (UPF0154) EF-hand_5 PF13202.1 KLO19581.1 - 0.0057 15.9 0.0 0.91 8.9 0.0 2.6 2 0 0 2 2 2 1 EF hand EFhand_Ca_insen PF08726.5 KLO19581.1 - 0.064 13.2 0.0 0.97 9.4 0.0 2.3 2 0 0 2 2 2 0 Ca2+ insensitive EF hand Glyco_hydro_3_C PF01915.17 KLO19583.1 - 2.9e-73 246.1 0.0 1.6e-72 243.7 0.0 2.0 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.16 KLO19583.1 - 4.8e-71 239.1 0.0 7e-71 238.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.1 KLO19583.1 - 1.9e-20 72.5 0.1 3.9e-20 71.5 0.1 1.6 1 0 0 1 1 1 1 Fibronectin type III-like domain PA14 PF07691.7 KLO19583.1 - 1.3e-09 37.8 0.0 3e-09 36.6 0.0 1.6 1 0 0 1 1 1 1 PA14 domain tRNA-synt_1b PF00579.20 KLO19585.1 - 5.4e-24 84.8 0.0 1.2e-23 83.6 0.0 1.6 1 1 0 1 1 1 1 tRNA synthetases class I (W and Y) PRTase_2 PF15609.1 KLO19586.1 - 0.11 11.7 0.1 0.17 11.1 0.0 1.2 1 0 0 1 1 1 0 Phosphoribosyl transferase eRF1_2 PF03464.10 KLO19587.1 - 2.8e-41 140.9 0.0 5.2e-41 140.1 0.0 1.5 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.10 KLO19587.1 - 6e-36 123.1 0.1 1.2e-35 122.1 0.0 1.5 1 0 0 1 1 1 1 eRF1 domain 3 eRF1_1 PF03463.10 KLO19587.1 - 1.2e-15 57.1 0.0 2.4e-15 56.3 0.0 1.5 1 0 0 1 1 1 1 eRF1 domain 1 p450 PF00067.17 KLO19588.1 - 4.2e-64 216.7 0.0 5.5e-64 216.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 FAD_binding_1 PF00667.15 KLO19588.1 - 9.3e-30 103.7 0.0 1.7e-29 102.8 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.20 KLO19588.1 - 8.9e-20 71.1 0.0 1.8e-19 70.1 0.0 1.5 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.16 KLO19588.1 - 2.5e-10 40.8 0.0 6.4e-10 39.5 0.0 1.7 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Flavodoxin_NdrI PF07972.6 KLO19588.1 - 0.013 15.4 0.0 0.035 13.9 0.0 1.8 1 0 0 1 1 1 0 NrdI Flavodoxin like SNARE PF05739.14 KLO19589.1 - 1.1e-08 34.6 0.0 1.5e-08 34.2 0.0 1.1 1 0 0 1 1 1 1 SNARE domain DUF1664 PF07889.7 KLO19589.1 - 0.067 12.9 0.1 0.067 12.9 0.1 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) DUF912 PF06024.7 KLO19591.1 - 2.9 7.9 0.0 2.9 7.9 0.0 3.7 3 1 1 4 4 4 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Shugoshin_N PF07558.6 KLO19592.1 - 1.4e-07 31.1 1.5 3.4e-07 29.8 1.0 1.7 1 0 0 1 1 1 1 Shugoshin N-terminal coiled-coil region Shugoshin_C PF07557.6 KLO19592.1 - 1.5e-07 30.7 4.5 1.5e-07 30.7 3.1 2.7 2 0 0 2 2 2 1 Shugoshin C terminus Mod_r PF07200.8 KLO19592.1 - 0.015 15.1 4.9 0.015 15.1 3.4 1.7 2 0 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein SnAC PF14619.1 KLO19592.1 - 0.16 12.1 9.0 0.69 10.1 0.0 3.7 3 0 0 3 3 3 0 Snf2-ATP coupling, chromatin remodelling complex DUF972 PF06156.8 KLO19592.1 - 6.8 7.0 10.0 0.37 11.1 1.3 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF972) C2 PF00168.25 KLO19594.1 - 7.9e-14 51.2 0.0 1.4e-13 50.5 0.0 1.4 1 0 0 1 1 1 1 C2 domain DBR1 PF05011.8 KLO19596.1 - 1.6e-33 115.6 0.0 2.4e-33 115.0 0.0 1.3 1 0 0 1 1 1 1 Lariat debranching enzyme, C-terminal domain Metallophos PF00149.23 KLO19596.1 - 4.7e-11 42.4 1.6 6.9e-11 41.9 1.1 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 KLO19596.1 - 0.00016 21.5 0.0 0.0003 20.6 0.0 1.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain WW PF00397.21 KLO19598.1 - 0.00039 20.2 2.3 0.0012 18.6 1.6 2.0 1 0 0 1 1 1 1 WW domain DUF202 PF02656.10 KLO19598.1 - 0.96 9.7 4.1 0.56 10.4 0.4 2.4 2 1 1 3 3 3 0 Domain of unknown function (DUF202) DctQ PF04290.7 KLO19598.1 - 4.4 7.0 13.8 90 2.8 0.7 3.1 1 1 2 3 3 3 0 Tripartite ATP-independent periplasmic transporters, DctQ component LRR_6 PF13516.1 KLO19599.1 - 6.6e-07 28.7 10.5 0.47 10.6 0.5 6.7 6 1 0 6 6 6 3 Leucine Rich repeat LRR_8 PF13855.1 KLO19599.1 - 0.00059 19.5 7.4 6.6 6.5 0.1 4.9 3 2 3 6 6 6 5 Leucine rich repeat LRR_7 PF13504.1 KLO19599.1 - 0.00069 19.3 8.3 2.5 8.6 0.1 6.5 8 0 0 8 8 8 2 Leucine rich repeat LRR_1 PF00560.28 KLO19599.1 - 0.061 13.3 11.4 0.26 11.4 0.4 5.8 5 1 0 5 5 5 0 Leucine Rich Repeat HATPase_c PF02518.21 KLO19600.1 - 3.4e-53 178.0 0.0 3.7e-27 94.2 0.0 2.6 2 0 0 2 2 2 2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 KLO19600.1 - 1.5e-46 157.0 1.0 4.6e-24 84.5 0.0 2.6 2 0 0 2 2 2 2 Response regulator receiver domain HisKA PF00512.20 KLO19600.1 - 6.5e-15 54.8 9.8 2e-10 40.4 0.0 3.2 3 1 0 3 3 3 2 His Kinase A (phospho-acceptor) domain PAS_9 PF13426.1 KLO19600.1 - 7.9e-06 26.1 0.0 0.052 13.9 0.0 3.8 4 0 0 4 4 4 2 PAS domain PAS_4 PF08448.5 KLO19600.1 - 9.4e-06 25.6 0.1 0.021 14.8 0.0 3.2 3 0 0 3 3 3 2 PAS fold HATPase_c_5 PF14501.1 KLO19600.1 - 6.2e-05 22.6 0.0 0.088 12.5 0.0 2.5 2 0 0 2 2 2 2 GHKL domain PAS_8 PF13188.1 KLO19600.1 - 8.9e-05 22.2 0.0 0.043 13.6 0.0 3.3 3 0 0 3 3 3 1 PAS domain HATPase_c_3 PF13589.1 KLO19600.1 - 0.00017 21.2 0.0 0.02 14.5 0.0 2.5 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PAS PF00989.19 KLO19600.1 - 0.007 16.1 0.0 0.054 13.2 0.0 2.5 2 0 0 2 2 2 1 PAS fold PAS_10 PF13596.1 KLO19600.1 - 0.0098 16.1 0.0 4.4 7.6 0.0 3.6 4 0 0 4 4 4 1 PAS domain MFS_1 PF07690.11 KLO19602.1 - 1.4e-40 139.1 43.5 7.1e-40 136.8 28.7 2.6 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KLO19602.1 - 1.5e-09 36.9 27.4 1.7e-08 33.5 10.2 3.1 1 1 1 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.8 KLO19602.1 - 4e-08 31.9 11.9 1.7e-07 29.8 7.3 2.1 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) MFS_2 PF13347.1 KLO19602.1 - 0.00061 18.2 2.7 0.00061 18.2 1.9 3.2 2 1 1 3 3 3 2 MFS/sugar transport protein Cyclase PF04199.8 KLO19603.1 - 7.6e-14 51.7 0.5 1.7e-13 50.5 0.4 1.6 1 1 0 1 1 1 1 Putative cyclase Pkinase PF00069.20 KLO19604.1 - 1e-48 165.8 0.0 1.5e-48 165.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KLO19604.1 - 4.3e-24 84.9 0.0 7.9e-24 84.1 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pox_ser-thr_kin PF05445.6 KLO19604.1 - 0.0045 15.8 0.0 0.0067 15.2 0.0 1.1 1 0 0 1 1 1 1 Poxvirus serine/threonine protein kinase RIO1 PF01163.17 KLO19604.1 - 0.032 13.5 4.4 0.31 10.3 0.0 3.5 2 1 1 3 3 3 0 RIO1 family BRCT PF00533.21 KLO19605.1 - 0.0016 18.5 0.0 0.0037 17.3 0.0 1.6 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain Myb_DNA-bind_2 PF08914.6 KLO19605.1 - 0.0036 17.0 0.6 0.015 15.1 0.4 2.0 1 1 0 1 1 1 1 Rap1 Myb domain HSP70 PF00012.15 KLO19606.1 - 0.0014 16.6 0.4 0.0034 15.3 0.1 1.7 2 0 0 2 2 2 1 Hsp70 protein Peptidase_M23 PF01551.17 KLO19606.1 - 0.03 14.3 0.0 0.066 13.2 0.0 1.6 1 0 0 1 1 1 0 Peptidase family M23 Sas10_Utp3 PF04000.10 KLO19608.1 - 6.4e-08 32.6 0.1 6.4e-08 32.6 0.1 1.7 2 0 0 2 2 2 1 Sas10/Utp3/C1D family RNA_pol_Rbc25 PF08292.7 KLO19609.1 - 0.04 14.1 0.1 0.069 13.3 0.1 1.4 1 1 0 1 1 1 0 RNA polymerase III subunit Rpc25 DUF4378 PF14309.1 KLO19609.1 - 0.1 12.6 0.3 0.15 12.0 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4378) DUF2413 PF10310.4 KLO19609.1 - 3.2 6.4 9.3 4.2 6.0 6.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) zf-primase PF09329.6 KLO19609.1 - 8.5 6.0 15.1 0.42 10.2 0.4 3.7 3 2 0 3 3 3 0 Primase zinc finger zf-primase PF09329.6 KLO19611.1 - 0.0064 16.0 1.2 0.018 14.6 0.8 1.7 1 1 0 1 1 1 1 Primase zinc finger Lactamase_B_2 PF12706.2 KLO19612.1 - 6.9e-34 117.0 0.1 9.2e-34 116.6 0.1 1.2 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 KLO19612.1 - 4.2e-11 42.8 0.0 7.8e-11 41.9 0.0 1.5 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 KLO19612.1 - 0.03 13.9 0.4 0.19 11.3 0.1 2.2 2 0 0 2 2 2 0 Metallo-beta-lactamase superfamily IncA PF04156.9 KLO19613.1 - 0.016 14.8 7.2 0.031 13.8 5.0 1.4 1 0 0 1 1 1 0 IncA protein Baculo_PEP_C PF04513.7 KLO19613.1 - 0.054 13.3 0.1 0.1 12.4 0.0 1.3 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Mnd1 PF03962.10 KLO19613.1 - 0.071 12.7 2.8 0.092 12.4 1.0 1.8 1 1 1 2 2 2 0 Mnd1 family TMF_DNA_bd PF12329.3 KLO19613.1 - 0.51 10.1 5.7 8.4 6.2 2.7 2.9 2 1 0 2 2 2 0 TATA element modulatory factor 1 DNA binding DUF4200 PF13863.1 KLO19613.1 - 1.9 8.4 9.1 3.2 7.7 1.5 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) DivIC PF04977.10 KLO19613.1 - 5.5 6.5 8.0 3.9 7.0 0.2 3.1 2 1 1 3 3 3 0 Septum formation initiator DUF4140 PF13600.1 KLO19613.1 - 8.3 6.9 9.5 9 6.8 0.7 2.6 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) adh_short PF00106.20 KLO19614.1 - 9e-24 84.2 1.2 3.1e-23 82.5 0.8 1.7 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KLO19614.1 - 9.5e-23 81.2 0.7 1.8e-22 80.3 0.5 1.4 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KLO19614.1 - 7.2e-07 29.0 0.3 1.3e-06 28.2 0.2 1.4 1 1 0 1 1 1 1 KR domain Shikimate_DH PF01488.15 KLO19614.1 - 0.0034 17.4 0.4 0.0061 16.6 0.3 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase AA_kinase PF00696.23 KLO19614.1 - 0.021 14.3 0.3 0.024 14.1 0.2 1.4 1 1 0 1 1 1 0 Amino acid kinase family NAD_binding_10 PF13460.1 KLO19614.1 - 0.024 14.6 0.5 0.033 14.1 0.4 1.6 1 1 0 1 1 1 0 NADH(P)-binding THF_DHG_CYH_C PF02882.14 KLO19614.1 - 0.032 13.2 0.0 0.07 12.2 0.0 1.5 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain NmrA PF05368.8 KLO19614.1 - 0.041 13.1 0.1 0.06 12.6 0.1 1.3 1 0 0 1 1 1 0 NmrA-like family 3HCDH_N PF02737.13 KLO19614.1 - 0.049 13.2 1.5 0.063 12.9 0.3 1.7 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Dak1 PF02733.12 KLO19614.1 - 0.083 11.4 0.7 0.28 9.7 0.1 1.9 2 0 0 2 2 2 0 Dak1 domain AdoHcyase_NAD PF00670.16 KLO19614.1 - 0.092 12.5 0.5 0.19 11.5 0.3 1.4 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain MRP-S33 PF08293.6 KLO19615.1 - 4.1e-25 87.5 0.1 5.3e-25 87.2 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal subunit S27 SUV3_C PF12513.3 KLO19616.1 - 3.5e-14 51.9 0.1 8.2e-14 50.7 0.1 1.7 1 0 0 1 1 1 1 Mitochondrial degradasome RNA helicase subunit C terminal Helicase_C PF00271.26 KLO19616.1 - 5.5e-09 35.7 0.0 1.6e-08 34.3 0.0 1.7 2 0 0 2 2 2 1 Helicase conserved C-terminal domain Zn_clus PF00172.13 KLO19617.1 - 0.0016 18.3 12.3 0.0024 17.7 8.5 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Zn_clus PF00172.13 KLO19618.1 - 0.0012 18.7 7.3 0.0019 18.0 5.1 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF4010 PF13194.1 KLO19618.1 - 0.18 11.0 0.8 0.3 10.3 0.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4010) DUF2477 PF10631.4 KLO19618.1 - 0.57 10.3 6.2 5.7 7.1 0.7 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF2477) NmrA PF05368.8 KLO19619.1 - 3.1e-21 75.7 0.0 5.3e-20 71.6 0.0 2.1 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 KLO19619.1 - 1.2e-12 48.2 0.1 2.1e-11 44.1 0.1 2.2 1 1 0 1 1 1 1 NADH(P)-binding KR PF08659.5 KLO19619.1 - 2.1e-07 30.8 0.1 3.2e-07 30.1 0.1 1.3 1 0 0 1 1 1 1 KR domain adh_short PF00106.20 KLO19619.1 - 1.5e-05 24.9 0.2 2.6e-05 24.2 0.1 1.4 1 0 0 1 1 1 1 short chain dehydrogenase Epimerase PF01370.16 KLO19619.1 - 2.9e-05 23.5 0.0 4.9e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 KLO19619.1 - 0.0048 15.6 0.0 0.008 14.9 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family BNIP3 PF06553.7 KLO19620.1 - 6.9 5.9 8.6 5.7 6.2 1.4 2.4 2 0 0 2 2 2 0 BNIP3 DUF4407 PF14362.1 KLO19621.1 - 0.17 10.8 2.2 0.32 9.9 1.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Glycos_transf_1 PF00534.15 KLO19624.1 - 2.1e-23 82.5 0.0 7.1e-13 48.3 0.0 2.2 2 0 0 2 2 2 2 Glycosyl transferases group 1 Glyco_transf_4 PF13439.1 KLO19624.1 - 1.9e-11 43.9 0.1 3.6e-11 43.0 0.1 1.4 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.1 KLO19624.1 - 8.1e-10 39.0 0.0 1.8e-09 37.9 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_trans_1_4 PF13692.1 KLO19624.1 - 0.00031 20.8 0.1 0.0029 17.7 0.0 2.2 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.1 KLO19624.1 - 0.002 18.3 0.0 0.0046 17.2 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 Fer4_14 PF13394.1 KLO19624.1 - 0.1 12.6 0.0 0.19 11.7 0.0 1.4 1 0 0 1 1 1 0 4Fe-4S single cluster domain Pribosyltran_N PF13793.1 KLO19626.1 - 5.4e-47 158.3 0.3 8.4e-46 154.4 0.1 2.2 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.1 KLO19626.1 - 3.4e-34 118.1 0.9 1.3e-29 103.2 0.2 2.7 2 1 1 3 3 3 2 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.22 KLO19626.1 - 3.9e-15 55.6 0.5 3.6e-14 52.5 0.3 2.2 2 0 0 2 2 2 1 Phosphoribosyl transferase domain UPRTase PF14681.1 KLO19626.1 - 5.4e-06 25.7 0.1 1e-05 24.8 0.0 1.4 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase PRTase_2 PF15609.1 KLO19626.1 - 0.081 12.2 0.1 0.2 10.9 0.1 1.6 1 0 0 1 1 1 0 Phosphoribosyl transferase Hist_deacetyl PF00850.14 KLO19627.1 - 7.2e-78 262.0 0.1 9.9e-78 261.5 0.0 1.1 1 0 0 1 1 1 1 Histone deacetylase domain MgtE PF01769.11 KLO19628.1 - 2.1e-22 79.8 29.8 1.1e-08 35.5 4.9 4.0 3 1 1 4 4 4 3 Divalent cation transporter Ada3 PF10198.4 KLO19629.1 - 1e-27 96.4 0.0 1e-27 96.4 0.0 2.4 3 0 0 3 3 3 1 Histone acetyltransferases subunit 3 F-box-like PF12937.2 KLO19630.1 - 0.0051 16.5 0.0 0.012 15.3 0.0 1.7 1 0 0 1 1 1 1 F-box-like DIOX_N PF14226.1 KLO19631.1 - 3.2e-19 69.5 0.1 7.7e-19 68.3 0.0 1.6 2 0 0 2 2 2 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 KLO19631.1 - 6.9e-10 39.1 0.0 2e-09 37.6 0.0 1.9 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily Amino_oxidase PF01593.19 KLO19632.1 - 2.9e-43 148.5 0.1 1.2e-29 103.6 0.0 2.1 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 KLO19632.1 - 1.5e-11 44.1 0.2 4.1e-11 42.7 0.0 1.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 KLO19632.1 - 0.0086 16.1 0.0 0.049 13.6 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 KLO19632.1 - 0.035 14.4 0.4 0.096 13.1 0.1 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 KLO19632.1 - 0.047 12.7 0.3 0.069 12.1 0.2 1.2 1 0 0 1 1 1 0 FAD binding domain VWA_2 PF13519.1 KLO19633.1 - 3.9e-11 43.3 0.1 7.1e-11 42.5 0.0 1.5 1 1 0 1 1 1 1 von Willebrand factor type A domain Med25_VWA PF11265.3 KLO19633.1 - 5.8e-06 25.4 0.0 1.1e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 Mediator complex subunit 25 von Willebrand factor type A VWA PF00092.23 KLO19633.1 - 0.0011 18.7 0.0 0.002 17.8 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain RicinB_lectin_2 PF14200.1 KLO19633.1 - 0.04 14.2 1.1 0.12 12.7 0.2 2.4 2 1 0 2 2 2 0 Ricin-type beta-trefoil lectin domain-like Integrin_beta PF00362.13 KLO19633.1 - 0.044 12.6 0.0 0.073 11.9 0.0 1.3 1 0 0 1 1 1 0 Integrin, beta chain LRRNT PF01462.13 KLO19634.1 - 0.17 11.4 1.6 0.24 10.9 1.1 1.2 1 0 0 1 1 1 0 Leucine rich repeat N-terminal domain VWA_2 PF13519.1 KLO19635.1 - 1.3e-09 38.4 0.9 1.9e-09 37.8 0.6 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.23 KLO19635.1 - 3.5e-06 26.8 0.0 7.5e-06 25.7 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain Integrin_beta PF00362.13 KLO19635.1 - 0.00025 20.0 0.1 0.0018 17.2 0.0 2.0 1 1 0 1 1 1 1 Integrin, beta chain Dyp_perox PF04261.7 KLO19635.1 - 0.0026 16.5 0.0 0.061 12.0 0.0 2.5 3 0 0 3 3 3 1 Dyp-type peroxidase family Med25_VWA PF11265.3 KLO19635.1 - 0.0031 16.5 0.0 0.0051 15.8 0.0 1.3 1 0 0 1 1 1 1 Mediator complex subunit 25 von Willebrand factor type A RNA_polI_A34 PF08208.6 KLO19636.1 - 1.2e-13 51.1 0.7 1.2e-13 51.1 0.5 2.1 2 0 0 2 2 2 1 DNA-directed RNA polymerase I subunit RPA34.5 DUF2673 PF10880.3 KLO19636.1 - 0.087 12.8 1.4 3.3 7.8 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2673) Rtf2 PF04641.7 KLO19636.1 - 4.3 6.4 14.2 0.054 12.7 0.5 2.1 2 0 0 2 2 2 0 Rtf2 RING-finger HhH-GPD PF00730.20 KLO19637.1 - 3e-20 72.4 0.0 5.1e-20 71.7 0.0 1.4 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.18 KLO19637.1 - 2.6e-08 33.0 0.0 6.7e-08 31.8 0.0 1.7 2 0 0 2 2 2 1 Helix-hairpin-helix motif HHH_5 PF14520.1 KLO19637.1 - 0.016 15.3 0.1 0.094 12.8 0.0 2.1 2 1 0 2 2 2 0 Helix-hairpin-helix domain EndIII_4Fe-2S PF10576.4 KLO19637.1 - 0.19 11.9 2.5 0.41 10.9 1.7 1.6 1 0 0 1 1 1 0 Iron-sulfur binding domain of endonuclease III Phos_pyr_kin PF08543.7 KLO19638.1 - 6.2e-82 274.4 0.5 2.3e-80 269.3 0.4 2.2 1 1 0 1 1 1 1 Phosphomethylpyrimidine kinase TENA_THI-4 PF03070.11 KLO19638.1 - 1.1e-48 165.7 0.3 1.5e-48 165.3 0.2 1.2 1 0 0 1 1 1 1 TENA/THI-4/PQQC family HK PF02110.10 KLO19638.1 - 0.0069 15.5 0.2 3.1 6.8 0.0 2.4 2 0 0 2 2 2 2 Hydroxyethylthiazole kinase family PfkB PF00294.19 KLO19638.1 - 0.018 14.2 0.0 0.047 12.8 0.0 1.7 2 0 0 2 2 2 0 pfkB family carbohydrate kinase Campylo_MOMP PF05538.6 KLO19638.1 - 0.034 12.5 0.0 0.051 11.9 0.0 1.2 1 0 0 1 1 1 0 Campylobacter major outer membrane protein FANCI_HD2 PF14680.1 KLO19638.1 - 0.1 11.6 0.0 0.17 10.9 0.0 1.4 1 0 0 1 1 1 0 FANCI helical domain 2 tRNA-synt_1b PF00579.20 KLO19639.1 - 2.4e-72 243.5 0.0 2.9e-72 243.2 0.0 1.0 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) Mak10 PF04112.8 KLO19640.1 - 4.8e-36 123.5 0.0 8.3e-36 122.7 0.0 1.4 1 0 0 1 1 1 1 Mak10 subunit, NatC N(alpha)-terminal acetyltransferase DUF2185 PF09951.4 KLO19640.1 - 0.14 11.9 0.0 1 9.1 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2185) Zn_clus PF00172.13 KLO19641.1 - 0.0013 18.6 9.7 0.0023 17.8 6.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain VCBS PF13517.1 KLO19645.1 - 0.082 13.2 0.6 0.33 11.3 0.3 2.0 1 1 1 2 2 2 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella Peptidase_M50B PF13398.1 KLO19646.1 - 1.4e-54 184.5 18.2 2.5e-54 183.7 12.6 1.3 1 0 0 1 1 1 1 Peptidase M50B-like DUF92 PF01940.11 KLO19646.1 - 0.86 8.7 10.3 0.66 9.0 0.1 2.9 1 1 0 2 2 2 0 Integral membrane protein DUF92 zf-C2H2 PF00096.21 KLO19647.1 - 3.2e-12 46.0 14.4 0.00015 21.9 0.8 3.2 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 KLO19647.1 - 1.4e-10 40.9 13.1 1.2e-05 25.3 0.2 3.6 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 KLO19647.1 - 2.9e-10 39.7 13.2 0.00089 19.4 0.4 3.2 3 0 0 3 3 3 3 C2H2-type zinc finger zf-TRAF PF02176.13 KLO19647.1 - 0.0066 16.8 2.0 0.0066 16.8 1.4 2.1 1 1 1 2 2 2 1 TRAF-type zinc finger zf-met PF12874.2 KLO19647.1 - 0.0093 16.1 8.3 3.4 8.0 0.4 3.5 3 0 0 3 3 3 2 Zinc-finger of C2H2 type IBR PF01485.16 KLO19647.1 - 0.012 15.4 5.4 0.21 11.4 1.3 2.1 1 1 1 2 2 2 0 IBR domain Zn-ribbon_8 PF09723.5 KLO19647.1 - 0.16 11.9 3.6 18 5.3 0.0 3.2 3 0 0 3 3 3 0 Zinc ribbon domain zf-C2H2_6 PF13912.1 KLO19647.1 - 0.54 10.2 9.1 1.8 8.5 0.0 3.1 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 KLO19647.1 - 1.8 8.7 10.7 9.9 6.4 0.4 3.4 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding CHORD PF04968.7 KLO19647.1 - 3.2 8.0 7.8 13 6.1 0.1 2.7 1 1 2 3 3 3 0 CHORD OrfB_Zn_ribbon PF07282.6 KLO19647.1 - 5.6 6.6 6.0 14 5.4 0.2 2.8 1 1 2 3 3 3 0 Putative transposase DNA-binding domain Syndecan PF01034.15 KLO19650.1 - 0.0075 15.9 0.0 0.013 15.1 0.0 1.3 1 0 0 1 1 1 1 Syndecan domain TMEM171 PF15471.1 KLO19650.1 - 0.32 9.7 3.6 0.42 9.3 1.4 1.9 1 1 1 2 2 2 0 Transmembrane protein family 171 OppC_N PF12911.2 KLO19652.1 - 0.0069 15.7 1.2 0.017 14.4 0.8 1.6 1 0 0 1 1 1 1 N-terminal TM domain of oligopeptide transport permease C TMEM51 PF15345.1 KLO19652.1 - 0.059 13.0 0.0 0.16 11.6 0.0 1.7 2 0 0 2 2 2 0 Transmembrane protein 51 UCH PF00443.24 KLO19657.1 - 1.6e-47 161.8 0.0 6.7e-47 159.8 0.0 1.8 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.14 KLO19657.1 - 7.8e-28 96.3 12.0 1.1e-21 76.7 1.4 2.8 2 0 0 2 2 2 2 Zn-finger in ubiquitin-hydrolases and other protein UBA PF00627.26 KLO19657.1 - 1.2e-23 82.2 1.6 4.5e-11 42.2 0.0 2.6 2 0 0 2 2 2 2 UBA/TS-N domain UCH_1 PF13423.1 KLO19657.1 - 5.7e-19 68.6 0.0 7e-18 65.0 0.0 2.6 2 2 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase Brix PF04427.13 KLO19658.1 - 1.1e-31 110.0 0.3 1.4e-31 109.6 0.2 1.1 1 0 0 1 1 1 1 Brix domain Nucleoplasmin PF03066.10 KLO19658.1 - 0.031 13.7 4.6 0.18 11.2 3.9 1.7 2 0 0 2 2 2 0 Nucleoplasmin DUF4611 PF15387.1 KLO19658.1 - 1.2 9.3 8.6 2.4 8.3 6.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) F-box-like PF12937.2 KLO19659.1 - 0.0036 16.9 0.0 0.0083 15.8 0.0 1.7 1 0 0 1 1 1 1 F-box-like DUF2183 PF09949.4 KLO19659.1 - 0.12 12.2 0.0 7 6.6 0.0 2.5 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2183) zf-C2H2 PF00096.21 KLO19661.1 - 2.8e-07 30.4 10.6 0.00022 21.3 1.2 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KLO19661.1 - 1.3e-05 25.2 9.7 0.012 15.8 0.6 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 KLO19661.1 - 8.9e-05 22.5 3.8 8.9e-05 22.5 2.6 2.3 2 0 0 2 2 2 1 Zinc-finger double domain zf-C2H2_6 PF13912.1 KLO19661.1 - 0.023 14.6 0.7 0.091 12.7 0.2 2.1 2 0 0 2 2 2 0 C2H2-type zinc finger Hat1_N PF10394.4 KLO19663.1 - 1.4e-43 148.7 0.8 2.7e-43 147.8 0.6 1.5 1 0 0 1 1 1 1 Histone acetyl transferase HAT1 N-terminus Acetyltransf_10 PF13673.1 KLO19663.1 - 0.0042 17.1 0.0 0.0095 16.0 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 KLO19663.1 - 0.017 15.2 0.2 2.2 8.4 0.0 2.3 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 KLO19663.1 - 0.086 12.8 0.0 0.16 11.9 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family Ribonuclease_3 PF00636.21 KLO19664.1 - 9.5e-42 142.0 0.0 5.6e-20 71.9 0.0 2.8 2 0 0 2 2 2 2 Ribonuclease III domain Ribonucleas_3_3 PF14622.1 KLO19664.1 - 8.1e-26 90.4 0.1 8.2e-15 54.9 0.0 4.2 2 2 0 2 2 2 2 Ribonuclease-III-like ResIII PF04851.10 KLO19664.1 - 2.7e-16 59.9 0.0 5.7e-16 58.8 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.26 KLO19664.1 - 1.2e-15 57.1 0.0 3.3e-15 55.7 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 KLO19664.1 - 1.8e-14 53.6 0.0 5e-14 52.1 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Dicer_dimer PF03368.9 KLO19664.1 - 1.5e-12 47.1 0.0 3.1e-12 46.0 0.0 1.6 1 0 0 1 1 1 1 Dicer dimerisation domain SNF2_N PF00176.18 KLO19664.1 - 0.00017 20.4 0.2 0.0004 19.2 0.0 1.7 2 0 0 2 2 2 1 SNF2 family N-terminal domain AAA_26 PF13500.1 KLO19664.1 - 0.17 11.4 0.0 0.37 10.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain Phosducin PF02114.11 KLO19665.1 - 2.1e-09 36.5 0.0 3.3e-09 35.8 0.0 1.2 1 0 0 1 1 1 1 Phosducin NADH-G_4Fe-4S_3 PF10588.4 KLO19667.1 - 0.15 11.3 3.2 6 6.1 0.0 2.4 2 0 0 2 2 2 0 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region DUF1675 PF07897.6 KLO19668.1 - 0.088 12.6 5.5 0.099 12.4 3.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) Herpes_Helicase PF02689.9 KLO19668.1 - 0.11 10.1 0.7 0.12 10.0 0.5 1.0 1 0 0 1 1 1 0 Helicase DUF4603 PF15376.1 KLO19668.1 - 2 5.5 9.1 2.4 5.2 6.3 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4603) alpha-hel2 PF14456.1 KLO19668.1 - 3.5 6.3 8.3 5.2 5.7 5.8 1.3 1 1 0 1 1 1 0 Alpha-helical domain 2 Hid1 PF12722.2 KLO19668.1 - 3.6 5.1 7.6 3.9 5.0 5.3 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Band_3_cyto PF07565.8 KLO19668.1 - 4.3 6.7 7.1 5.4 6.4 4.9 1.1 1 0 0 1 1 1 0 Band 3 cytoplasmic domain DUF2589 PF11655.3 KLO19669.1 - 0.0046 17.0 4.5 0.037 14.1 0.5 2.7 2 0 0 2 2 2 1 Protein of unknown function (DUF2589) Porin_4 PF13609.1 KLO19669.1 - 0.0067 15.9 0.2 0.06 12.8 0.1 2.0 2 0 0 2 2 2 1 Gram-negative porin CENP-F_leu_zip PF10473.4 KLO19669.1 - 0.11 12.3 12.9 0.32 10.8 9.0 1.8 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 2OG-Fe_Oxy_2 PF10014.4 KLO19669.1 - 0.11 11.8 0.7 0.24 10.7 0.5 1.5 1 0 0 1 1 1 0 2OG-Fe dioxygenase GAS PF13851.1 KLO19669.1 - 0.61 9.2 18.4 0.087 12.0 8.7 2.2 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding Spectrin PF00435.16 KLO19669.1 - 6.3 7.1 15.0 0.37 11.1 2.0 3.6 2 1 1 3 3 3 0 Spectrin repeat zf-DHHC PF01529.15 KLO19671.1 - 3.3e-34 117.7 4.4 5.9e-34 116.9 3.1 1.4 1 0 0 1 1 1 1 DHHC palmitoyltransferase DctQ PF04290.7 KLO19671.1 - 0.93 9.2 12.4 0.37 10.5 2.9 2.2 2 0 0 2 2 2 0 Tripartite ATP-independent periplasmic transporters, DctQ component OPA3 PF07047.7 KLO19673.1 - 2.3e-33 114.8 0.1 3.2e-33 114.3 0.0 1.1 1 0 0 1 1 1 1 Optic atrophy 3 protein (OPA3) FlxA PF14282.1 KLO19673.1 - 0.0098 15.8 0.3 0.017 15.0 0.2 1.4 1 0 0 1 1 1 1 FlxA-like protein BLOC1_2 PF10046.4 KLO19673.1 - 0.012 15.7 0.4 0.076 13.1 0.1 2.0 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Spc7 PF08317.6 KLO19673.1 - 0.025 13.2 0.1 0.036 12.7 0.1 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein Mod_r PF07200.8 KLO19673.1 - 0.029 14.2 0.6 0.24 11.2 0.5 2.2 1 1 1 2 2 2 0 Modifier of rudimentary (Mod(r)) protein EAP30 PF04157.11 KLO19673.1 - 0.031 13.4 0.7 0.96 8.5 0.1 2.1 2 0 0 2 2 2 0 EAP30/Vps36 family YycI PF09648.5 KLO19673.1 - 0.082 12.3 0.1 0.13 11.6 0.1 1.3 1 0 0 1 1 1 0 YycH protein MbeD_MobD PF04899.7 KLO19673.1 - 0.14 12.0 0.4 0.14 12.0 0.3 1.9 2 0 0 2 2 2 0 MbeD/MobD like FlaC_arch PF05377.6 KLO19673.1 - 0.14 12.0 0.4 0.34 10.8 0.3 1.6 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) Cellulase PF00150.13 KLO19675.1 - 2e-12 46.8 0.0 4e-08 32.7 0.0 2.8 2 1 0 2 2 2 2 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_35 PF01301.14 KLO19675.1 - 0.063 12.6 0.1 0.1 11.8 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolases family 35 IPK PF03770.11 KLO19676.1 - 9.9e-43 146.0 0.0 1.4e-42 145.6 0.0 1.2 1 0 0 1 1 1 1 Inositol polyphosphate kinase RXT2_N PF08595.6 KLO19676.1 - 0.15 11.8 6.2 0.12 12.1 2.8 1.9 2 0 0 2 2 2 0 RXT2-like, N-terminal Rhabdo_ncap PF00945.13 KLO19676.1 - 0.56 8.7 2.0 0.79 8.2 1.4 1.1 1 0 0 1 1 1 0 Rhabdovirus nucleocapsid protein Nop14 PF04147.7 KLO19676.1 - 0.6 7.9 7.6 0.84 7.4 5.3 1.1 1 0 0 1 1 1 0 Nop14-like family Nucleoplasmin PF03066.10 KLO19676.1 - 1.4 8.4 12.5 3.1 7.3 8.7 1.5 1 0 0 1 1 1 0 Nucleoplasmin PI3K_1B_p101 PF10486.4 KLO19676.1 - 1.5 6.2 3.8 2 5.8 2.7 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit PBP1_TM PF14812.1 KLO19676.1 - 1.9 8.8 10.7 0.95 9.8 5.2 2.0 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Daxx PF03344.10 KLO19676.1 - 4 5.8 8.9 6.1 5.2 6.1 1.2 1 0 0 1 1 1 0 Daxx Family S-antigen PF05756.6 KLO19676.1 - 4.3 7.3 7.5 10 6.1 5.2 1.6 1 0 0 1 1 1 0 S-antigen protein FAM176 PF14851.1 KLO19676.1 - 6.9 6.3 6.9 0.92 9.1 1.8 1.7 2 0 0 2 2 2 0 FAM176 family CDC45 PF02724.9 KLO19676.1 - 10 4.0 8.4 16 3.3 5.8 1.2 1 0 0 1 1 1 0 CDC45-like protein Zn_clus PF00172.13 KLO19677.1 - 1.5e-05 24.8 12.9 2e-05 24.4 8.9 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain YyzF PF14116.1 KLO19677.1 - 0.36 10.8 3.4 1.7 8.6 0.0 2.1 1 1 1 2 2 2 0 YyzF-like protein DUF2318 PF10080.4 KLO19677.1 - 0.56 9.9 4.8 0.7 9.6 3.3 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2318) Lipase_3 PF01764.20 KLO19678.1 - 1.2e-06 28.1 0.0 3.3e-06 26.7 0.0 1.7 1 1 0 1 1 1 1 Lipase (class 3) Abhydrolase_5 PF12695.2 KLO19678.1 - 0.023 14.4 0.0 0.04 13.6 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family UPF0227 PF05728.7 KLO19678.1 - 0.075 12.7 0.0 0.15 11.7 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) DUF651 PF04895.7 KLO19678.1 - 0.15 11.7 0.1 0.33 10.5 0.0 1.6 2 0 0 2 2 2 0 Archaeal protein of unknown function (DUF651) IncA PF04156.9 KLO19679.1 - 0.00054 19.6 1.1 0.0009 18.8 0.3 1.6 2 0 0 2 2 2 1 IncA protein ALIX_LYPXL_bnd PF13949.1 KLO19679.1 - 0.018 14.0 2.5 0.082 11.8 1.7 2.0 1 1 0 1 1 1 0 ALIX V-shaped domain binding to HIV DUF342 PF03961.8 KLO19679.1 - 0.03 12.7 0.0 0.038 12.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Laminin_I PF06008.9 KLO19679.1 - 0.04 13.2 1.7 0.86 8.8 1.3 2.2 1 1 0 1 1 1 0 Laminin Domain I IMS PF00817.15 KLO19679.1 - 0.078 12.7 0.0 0.12 12.1 0.0 1.2 1 0 0 1 1 1 0 impB/mucB/samB family DUF4600 PF15372.1 KLO19679.1 - 0.084 13.0 0.9 0.25 11.5 0.0 2.0 2 1 0 2 2 2 0 Domain of unknown function (DUF4600) ACT_3 PF10000.4 KLO19679.1 - 0.11 12.2 0.3 0.21 11.3 0.2 1.5 1 0 0 1 1 1 0 ACT domain Vac_Fusion PF02346.11 KLO19679.1 - 0.12 11.7 0.6 6.2 6.3 0.1 3.2 3 1 0 3 3 3 0 Chordopoxvirus fusion protein Sec20 PF03908.8 KLO19679.1 - 0.15 11.7 0.1 1.2 8.8 0.1 2.1 2 0 0 2 2 2 0 Sec20 eIF2A PF08662.6 KLO19680.1 - 1.1e-69 234.0 0.0 1.3e-68 230.5 0.0 2.3 2 1 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A WD40 PF00400.27 KLO19680.1 - 0.0003 20.5 0.4 0.95 9.4 0.0 4.8 5 0 0 5 5 5 1 WD domain, G-beta repeat Proteasome_A_N PF10584.4 KLO19680.1 - 0.011 14.9 6.7 1.7 8.0 0.2 3.6 3 0 0 3 3 3 0 Proteasome subunit A N-terminal signature CDV3 PF15359.1 KLO19680.1 - 0.019 15.0 2.5 0.019 15.0 1.7 2.0 3 0 0 3 3 3 0 Carnitine deficiency-associated protein 3 Coatomer_WDAD PF04053.9 KLO19680.1 - 0.02 13.6 0.0 0.52 9.0 0.0 2.3 2 0 0 2 2 2 0 Coatomer WD associated region Zn_clus PF00172.13 KLO19681.1 - 0.0082 16.0 8.4 0.0082 16.0 5.8 2.1 2 1 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CLN3 PF02487.12 KLO19682.1 - 0.029 13.1 0.0 0.042 12.6 0.0 1.1 1 0 0 1 1 1 0 CLN3 protein LRR_8 PF13855.1 KLO19682.1 - 0.17 11.6 9.5 0.26 11.0 0.4 3.8 3 1 1 4 4 4 0 Leucine rich repeat LRR_4 PF12799.2 KLO19682.1 - 1.3 8.7 8.0 0.86 9.2 1.3 3.5 4 1 0 4 4 4 0 Leucine Rich repeats (2 copies) F-box-like PF12937.2 KLO19683.1 - 2.1e-07 30.5 1.4 9.4e-07 28.4 1.0 2.2 1 1 0 1 1 1 1 F-box-like LRR_4 PF12799.2 KLO19683.1 - 0.021 14.4 4.9 0.1 12.2 1.3 3.4 2 1 0 2 2 2 0 Leucine Rich repeats (2 copies) LRR_7 PF13504.1 KLO19683.1 - 0.095 12.9 5.2 14 6.4 0.2 5.8 4 3 1 5 5 5 0 Leucine rich repeat LRR_6 PF13516.1 KLO19683.1 - 0.28 11.3 1.3 5.4 7.4 0.0 3.7 3 1 0 3 3 3 0 Leucine Rich repeat LRR_8 PF13855.1 KLO19683.1 - 0.29 10.9 5.5 2.1 8.1 0.1 3.3 3 0 0 3 3 3 0 Leucine rich repeat Myb_DNA-bind_2 PF08914.6 KLO19684.1 - 1.8e-11 43.6 2.0 6.7e-11 41.8 1.4 2.0 1 0 0 1 1 1 1 Rap1 Myb domain Rap1_C PF11626.3 KLO19684.1 - 0.0021 17.9 0.6 0.01 15.7 0.0 2.4 3 0 0 3 3 3 1 TRF2-interacting telomeric protein/Rap1 - C terminal domain adh_short_C2 PF13561.1 KLO19685.1 - 1.3e-33 116.7 0.0 1.6e-33 116.5 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 KLO19685.1 - 7.7e-29 100.7 0.3 9.4e-29 100.4 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KLO19685.1 - 2.2e-12 47.0 0.1 3.2e-12 46.4 0.1 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 KLO19685.1 - 0.00031 20.2 0.0 0.0011 18.4 0.0 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.3 KLO19685.1 - 0.0019 17.9 0.4 0.0044 16.7 0.3 1.6 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase adh_short_C2 PF13561.1 KLO19686.1 - 8.4e-33 114.1 0.0 9.7e-33 113.9 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 KLO19686.1 - 4.6e-32 111.2 0.2 5.6e-32 110.9 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KLO19686.1 - 3.5e-15 56.1 0.0 4.8e-15 55.6 0.0 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 KLO19686.1 - 0.00059 19.3 0.1 0.00076 18.9 0.1 1.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.3 KLO19686.1 - 0.0061 16.3 0.5 0.012 15.4 0.3 1.5 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase F420_oxidored PF03807.12 KLO19686.1 - 0.02 15.2 0.5 0.039 14.3 0.3 1.6 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent HHH_5 PF14520.1 KLO19686.1 - 0.07 13.3 2.6 6.1 7.0 1.7 2.4 1 1 0 1 1 1 0 Helix-hairpin-helix domain THF_DHG_CYH_C PF02882.14 KLO19686.1 - 0.073 12.1 0.2 0.16 11.0 0.1 1.6 1 1 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain DUF1776 PF08643.5 KLO19686.1 - 0.075 12.1 0.0 0.094 11.8 0.0 1.3 1 1 0 1 1 1 0 Fungal family of unknown function (DUF1776) HAD PF12710.2 KLO19686.1 - 0.14 12.3 0.0 0.39 10.8 0.0 1.4 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase TRAUB PF08164.7 KLO19687.1 - 0.01 15.9 0.2 0.012 15.7 0.1 1.2 1 0 0 1 1 1 0 Apoptosis-antagonizing transcription factor, C-terminal HSP70 PF00012.15 KLO19688.1 - 7.6e-58 195.8 9.0 3.8e-41 140.7 0.2 3.3 3 1 0 3 3 3 2 Hsp70 protein MreB_Mbl PF06723.8 KLO19688.1 - 4.7e-06 25.4 0.0 1.6e-05 23.6 0.0 1.7 1 1 0 1 1 1 1 MreB/Mbl protein Myc_N PF01056.13 KLO19688.1 - 1.3 8.0 9.8 1.6 7.8 5.0 2.1 2 0 0 2 2 2 0 Myc amino-terminal region F-box-like PF12937.2 KLO19689.1 - 0.00045 19.8 0.0 0.00045 19.8 0.0 2.4 3 1 0 3 3 3 1 F-box-like PLDc_2 PF13091.1 KLO19690.1 - 1.6e-20 73.1 0.0 8.8e-13 48.1 0.0 2.4 2 0 0 2 2 2 2 PLD-like domain PLDc PF00614.17 KLO19690.1 - 0.0012 18.5 0.7 0.16 11.7 0.0 2.5 2 0 0 2 2 2 2 Phospholipase D Active site motif GPI-anchored PF10342.4 KLO19691.1 - 0.0059 17.0 0.0 0.0086 16.5 0.0 1.3 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family GPI-anchored PF10342.4 KLO19692.1 - 0.0031 17.9 0.0 0.0078 16.6 0.0 1.7 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family CD20 PF04103.10 KLO19693.1 - 0.076 12.9 5.8 1.6 8.6 0.5 2.2 1 1 1 2 2 2 0 CD20-like family GPI-anchored PF10342.4 KLO19695.1 - 2.1e-05 24.9 1.0 2.1e-05 24.9 0.7 1.9 2 0 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Claudin_2 PF13903.1 KLO19695.1 - 0.026 14.1 0.8 1.4 8.5 0.1 2.3 2 0 0 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction TMEM154 PF15102.1 KLO19696.1 - 0.012 15.3 0.1 0.017 14.8 0.0 1.2 1 0 0 1 1 1 0 TMEM154 protein family OppC_N PF12911.2 KLO19696.1 - 0.015 14.6 0.7 0.027 13.8 0.5 1.3 1 0 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C Cytadhesin_P30 PF07271.6 KLO19696.1 - 0.019 14.2 0.0 0.021 14.1 0.0 1.2 1 0 0 1 1 1 0 Cytadhesin P30/P32 DUF4366 PF14283.1 KLO19696.1 - 0.021 14.2 0.0 0.023 14.1 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) Herpes_gE PF02480.11 KLO19696.1 - 0.041 12.1 0.0 0.051 11.8 0.0 1.1 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E SKG6 PF08693.5 KLO19696.1 - 0.087 12.1 0.8 0.17 11.2 0.5 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain YjgP_YjgQ PF03739.9 KLO19696.1 - 0.1 11.3 0.0 0.11 11.2 0.0 1.0 1 0 0 1 1 1 0 Predicted permease YjgP/YjgQ family Halogen_Hydrol PF10112.4 KLO19696.1 - 0.1 12.0 0.0 0.14 11.5 0.0 1.2 1 0 0 1 1 1 0 5-bromo-4-chloroindolyl phosphate hydrolysis protein Pex14_N PF04695.8 KLO19696.1 - 1.2 9.2 4.8 0.41 10.6 1.4 1.6 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region TMEM51 PF15345.1 KLO19697.1 - 0.0048 16.6 0.1 0.0072 16.0 0.1 1.4 1 1 0 1 1 1 1 Transmembrane protein 51 Protocadherin PF08374.6 KLO19697.1 - 0.022 14.4 0.0 0.024 14.2 0.0 1.2 1 0 0 1 1 1 0 Protocadherin EphA2_TM PF14575.1 KLO19697.1 - 0.023 15.1 0.1 0.051 13.9 0.1 1.6 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain DUF202 PF02656.10 KLO19697.1 - 0.035 14.3 0.1 0.051 13.7 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF202) TMEM154 PF15102.1 KLO19698.1 - 0.004 16.8 0.3 0.004 16.8 0.2 2.1 2 0 0 2 2 2 1 TMEM154 protein family EphA2_TM PF14575.1 KLO19698.1 - 0.0045 17.3 0.2 0.0098 16.2 0.2 1.5 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain Herpes_gE PF02480.11 KLO19698.1 - 0.0056 15.0 0.2 0.0087 14.3 0.1 1.3 1 0 0 1 1 1 1 Alphaherpesvirus glycoprotein E Baculo_11_kDa PF06143.6 KLO19698.1 - 0.0087 15.4 0.2 0.022 14.1 0.1 1.6 1 0 0 1 1 1 1 Baculovirus 11 kDa family Protocadherin PF08374.6 KLO19698.1 - 0.011 15.4 0.0 0.015 14.9 0.0 1.3 1 0 0 1 1 1 0 Protocadherin TMEM51 PF15345.1 KLO19698.1 - 0.025 14.2 1.2 0.036 13.7 0.1 1.7 1 1 1 2 2 2 0 Transmembrane protein 51 PIRT PF15099.1 KLO19698.1 - 0.059 12.5 0.6 0.1 11.8 0.4 1.6 1 0 0 1 1 1 0 Phosphoinositide-interacting protein family Adeno_E3_CR2 PF02439.10 KLO19698.1 - 0.087 12.3 2.3 0.16 11.5 1.6 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Syndecan PF01034.15 KLO19698.1 - 0.12 12.0 0.1 0.19 11.4 0.1 1.3 1 0 0 1 1 1 0 Syndecan domain DUF3357 PF11837.3 KLO19698.1 - 0.22 11.3 3.7 0.13 12.0 0.6 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF3357) DUF912 PF06024.7 KLO19698.1 - 0.32 11.0 1.2 0.85 9.6 0.9 1.8 1 1 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) DUF1180 PF06679.7 KLO19698.1 - 0.42 10.4 4.7 0.87 9.4 3.2 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1180) Herpes_gE PF02480.11 KLO19699.1 - 0.0066 14.7 0.1 0.0083 14.4 0.0 1.2 1 0 0 1 1 1 1 Alphaherpesvirus glycoprotein E Rod_cone_degen PF15201.1 KLO19699.1 - 0.063 13.1 0.3 0.16 11.8 0.2 1.7 1 0 0 1 1 1 0 Progressive rod-cone degeneration OppC_N PF12911.2 KLO19699.1 - 0.81 9.1 2.5 1.4 8.3 1.3 1.7 1 1 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C DUF4245 PF14030.1 KLO19700.1 - 0.014 15.1 0.3 0.034 13.8 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF4245) BatD PF13584.1 KLO19700.1 - 0.016 13.8 0.1 0.02 13.4 0.1 1.3 1 0 0 1 1 1 0 Oxygen tolerance DUF2029 PF09594.5 KLO19700.1 - 0.018 14.5 0.0 0.027 13.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2029) TMEM190 PF15431.1 KLO19700.1 - 0.022 14.7 0.0 0.034 14.0 0.0 1.2 1 0 0 1 1 1 0 Transmembrane protein 190 DUF4234 PF14018.1 KLO19700.1 - 0.042 13.5 0.1 0.075 12.7 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4234) Keratin_B2 PF01500.12 KLO19700.1 - 0.34 10.6 3.4 0.51 10.0 2.4 1.2 1 0 0 1 1 1 0 Keratin, high sulfur B2 protein CcmD PF04995.9 KLO19701.1 - 0.12 12.0 0.6 0.22 11.2 0.4 1.3 1 0 0 1 1 1 0 Heme exporter protein D (CcmD) PgaD PF13994.1 KLO19702.1 - 0.0017 17.8 0.0 0.0029 17.0 0.0 1.3 1 0 0 1 1 1 1 PgaD-like protein RCR PF12273.3 KLO19702.1 - 0.086 13.3 0.1 0.73 10.4 0.0 2.3 2 0 0 2 2 2 0 Chitin synthesis regulation, resistance to Congo red FixQ PF05545.6 KLO19702.1 - 0.091 12.4 0.6 0.16 11.6 0.4 1.3 1 0 0 1 1 1 0 Cbb3-type cytochrome oxidase component FixQ P12 PF12669.2 KLO19702.1 - 0.1 12.8 0.3 0.18 12.0 0.2 1.3 1 0 0 1 1 1 0 Virus attachment protein p12 family Rifin_STEVOR PF02009.11 KLO19702.1 - 0.39 10.3 4.0 1.7 8.2 2.9 1.7 1 1 1 2 2 2 0 Rifin/stevor family DUF202 PF02656.10 KLO19702.1 - 1.9 8.7 6.0 6.3 7.0 4.1 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF202) DUF2730 PF10805.3 KLO19703.1 - 0.04 13.6 0.0 0.086 12.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2730) PgaD PF13994.1 KLO19703.1 - 0.13 11.7 0.6 0.2 11.1 0.0 1.6 2 0 0 2 2 2 0 PgaD-like protein K1 PF02960.9 KLO19703.1 - 0.9 9.5 4.9 1.5 8.8 3.4 1.4 1 0 0 1 1 1 0 K1 glycoprotein DUF3405 PF11885.3 KLO19704.1 - 0.077 11.2 0.0 0.095 10.9 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3405) SKG6 PF08693.5 KLO19706.1 - 0.17 11.2 2.7 0.36 10.1 1.9 1.6 1 0 0 1 1 1 0 Transmembrane alpha-helix domain TMEM52 PF14979.1 KLO19706.1 - 0.65 9.8 3.4 2.1 8.1 1.5 2.2 2 0 0 2 2 2 0 Transmembrane 52 CytochromB561_N PF09786.4 KLO19706.1 - 1.2 7.5 10.0 1.8 6.9 6.9 1.3 1 0 0 1 1 1 0 Cytochrome B561, N terminal F-box-like PF12937.2 KLO19707.1 - 2.7e-06 26.9 2.2 7.9e-06 25.4 1.5 1.8 1 0 0 1 1 1 1 F-box-like DUF1191 PF06697.7 KLO19708.1 - 0.0059 15.4 0.1 0.0075 15.1 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1191) MSC PF09402.5 KLO19708.1 - 0.11 11.2 0.0 0.15 10.7 0.0 1.1 1 0 0 1 1 1 0 Man1-Src1p-C-terminal domain DUF566 PF04484.7 KLO19708.1 - 0.16 11.4 4.7 0.23 10.9 3.3 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF566) Peptidase_C24 PF03510.9 KLO19708.1 - 5 7.3 7.7 3.2 7.9 2.1 2.6 2 1 0 2 2 2 0 2C endopeptidase (C24) cysteine protease family Alpha_GJ PF03229.8 KLO19708.1 - 7.5 6.9 15.3 0.087 13.1 1.4 2.5 1 1 1 2 2 2 0 Alphavirus glycoprotein J Microtub_assoc PF07989.6 KLO19711.1 - 2.5e-22 78.4 9.6 2.5e-22 78.4 6.6 11.1 8 2 5 13 13 13 1 Microtubule associated Reo_sigmaC PF04582.7 KLO19711.1 - 2.4e-05 23.6 36.9 0.0029 16.8 0.5 6.8 3 1 6 9 9 9 6 Reovirus sigma C capsid protein GAS PF13851.1 KLO19711.1 - 0.0063 15.7 10.6 0.0063 15.7 7.4 8.8 2 2 5 8 8 8 4 Growth-arrest specific micro-tubule binding AAA_13 PF13166.1 KLO19711.1 - 0.081 11.3 111.6 0.056 11.9 16.5 5.0 2 1 3 5 5 5 0 AAA domain MFS_1 PF07690.11 KLO19712.1 - 3.1e-38 131.3 29.1 3.1e-38 131.3 20.2 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily WD40 PF00400.27 KLO19716.1 - 2.9e-28 96.6 20.8 7.3e-10 38.3 1.8 6.2 6 0 0 6 6 6 5 WD domain, G-beta repeat NACHT PF05729.7 KLO19716.1 - 1.1e-14 54.3 0.0 2.6e-14 53.2 0.0 1.6 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 KLO19716.1 - 4.1e-06 26.9 0.0 1.2e-05 25.4 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain Zeta_toxin PF06414.7 KLO19716.1 - 0.00091 18.3 0.0 0.0016 17.5 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin DUF2075 PF09848.4 KLO19716.1 - 0.0025 16.8 0.0 0.0086 15.0 0.0 1.8 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) AAA_22 PF13401.1 KLO19716.1 - 0.017 15.2 0.0 0.046 13.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.1 KLO19716.1 - 0.03 14.0 0.0 0.096 12.4 0.0 1.8 1 0 0 1 1 1 0 Part of AAA domain NB-ARC PF00931.17 KLO19716.1 - 0.031 13.1 0.0 0.054 12.3 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain RNA_helicase PF00910.17 KLO19716.1 - 0.088 12.9 0.0 0.24 11.6 0.0 1.7 1 0 0 1 1 1 0 RNA helicase AAA PF00004.24 KLO19716.1 - 0.094 12.9 0.1 0.34 11.1 0.0 2.0 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.1 KLO19716.1 - 0.12 11.7 0.1 0.44 9.9 0.1 1.9 1 1 0 1 1 1 0 AAA domain AAA_11 PF13086.1 KLO19716.1 - 0.14 11.7 0.0 0.25 10.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain UPF0079 PF02367.12 KLO19716.1 - 0.15 11.7 0.0 0.34 10.5 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 Arch_ATPase PF01637.13 KLO19716.1 - 0.15 11.7 0.0 0.39 10.3 0.0 1.7 1 0 0 1 1 1 0 Archaeal ATPase KAP_NTPase PF07693.9 KLO19716.1 - 0.38 9.7 2.7 11 4.9 0.9 2.3 1 1 1 2 2 2 0 KAP family P-loop domain WD40 PF00400.27 KLO19718.1 - 2.1e-34 116.1 31.9 1.7e-11 43.5 0.5 8.8 8 0 0 8 8 8 6 WD domain, G-beta repeat NACHT PF05729.7 KLO19718.1 - 8.9e-20 70.9 0.1 2.2e-08 33.9 0.0 3.5 2 2 0 2 2 2 2 NACHT domain AAA_16 PF13191.1 KLO19718.1 - 1.8e-17 63.9 0.0 9.7e-09 35.4 0.0 2.8 2 0 0 2 2 2 2 AAA ATPase domain AAA PF00004.24 KLO19718.1 - 7.5e-09 35.8 0.0 0.0025 18.0 0.0 4.2 3 2 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) NB-ARC PF00931.17 KLO19718.1 - 3.5e-07 29.3 0.0 0.019 13.8 0.0 2.5 2 0 0 2 2 2 2 NB-ARC domain Zeta_toxin PF06414.7 KLO19718.1 - 1.6e-06 27.3 0.0 0.05 12.6 0.0 2.4 2 0 0 2 2 2 2 Zeta toxin KAP_NTPase PF07693.9 KLO19718.1 - 1.6e-06 27.3 1.2 0.33 9.9 0.1 4.2 4 0 0 4 4 4 2 KAP family P-loop domain AAA_19 PF13245.1 KLO19718.1 - 1.7e-06 27.6 0.0 0.065 13.0 0.0 3.3 3 0 0 3 3 3 2 Part of AAA domain DUF2075 PF09848.4 KLO19718.1 - 3.7e-06 26.1 0.0 0.06 12.3 0.0 2.4 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2075) APS_kinase PF01583.15 KLO19718.1 - 6e-06 26.0 0.0 0.063 12.9 0.0 2.7 2 0 0 2 2 2 2 Adenylylsulphate kinase AAA_22 PF13401.1 KLO19718.1 - 1.8e-05 24.8 0.0 0.24 11.5 0.0 2.8 2 0 0 2 2 2 2 AAA domain RNA_helicase PF00910.17 KLO19718.1 - 5e-05 23.4 0.0 0.36 11.0 0.0 3.0 2 0 0 2 2 2 2 RNA helicase AAA_25 PF13481.1 KLO19718.1 - 0.00054 19.4 1.3 0.18 11.1 0.1 3.2 3 1 0 3 3 3 1 AAA domain AAA_17 PF13207.1 KLO19718.1 - 0.00092 20.0 0.6 1.1 10.1 0.0 3.5 2 2 0 2 2 2 1 AAA domain AAA_18 PF13238.1 KLO19718.1 - 0.0035 17.6 0.0 5.3 7.3 0.0 2.9 2 0 0 2 2 2 0 AAA domain Arch_ATPase PF01637.13 KLO19718.1 - 0.0057 16.3 0.0 2.3 7.8 0.0 2.5 2 0 0 2 2 2 1 Archaeal ATPase AAA_14 PF13173.1 KLO19718.1 - 0.0078 16.1 0.0 23 4.8 0.0 3.9 3 0 0 3 3 3 0 AAA domain Viral_helicase1 PF01443.13 KLO19718.1 - 0.01 15.3 0.0 3.5 7.0 0.0 2.6 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase TIP49 PF06068.8 KLO19718.1 - 0.01 14.5 0.0 0.65 8.6 0.0 2.3 2 0 0 2 2 2 0 TIP49 C-terminus NTPase_1 PF03266.10 KLO19718.1 - 0.011 15.3 0.0 7 6.3 0.0 2.8 3 0 0 3 3 2 0 NTPase AAA_11 PF13086.1 KLO19718.1 - 0.016 14.8 0.0 6 6.3 0.0 2.4 2 0 0 2 2 2 0 AAA domain Mg_chelatase PF01078.16 KLO19718.1 - 0.029 13.5 0.0 1.5 7.9 0.0 2.3 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI DnaB_C PF03796.10 KLO19718.1 - 0.03 13.1 0.0 1.6 7.5 0.0 2.3 2 0 0 2 2 2 0 DnaB-like helicase C terminal domain cobW PF02492.14 KLO19718.1 - 0.034 13.5 0.2 3.3 7.1 0.0 2.6 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_10 PF12846.2 KLO19718.1 - 0.038 13.4 0.0 7.7 5.8 0.0 2.7 2 0 0 2 2 2 0 AAA-like domain UPF0079 PF02367.12 KLO19718.1 - 0.075 12.6 0.0 4.4 6.9 0.0 2.7 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 Parvo_NS1 PF01057.12 KLO19718.1 - 0.099 11.4 0.0 1.4 7.7 0.0 2.1 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 AAA_33 PF13671.1 KLO19718.1 - 0.1 12.4 0.1 17 5.2 0.0 2.6 2 0 0 2 2 2 0 AAA domain FtsK_SpoIIIE PF01580.13 KLO19718.1 - 0.13 11.7 0.1 24 4.2 0.0 2.8 3 0 0 3 3 2 0 FtsK/SpoIIIE family PIF1 PF05970.9 KLO19718.1 - 0.14 11.0 0.0 2.5 6.9 0.0 2.3 2 0 0 2 2 2 0 PIF1-like helicase AAA_23 PF13476.1 KLO19718.1 - 0.17 12.2 0.0 14 5.9 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.1 KLO19718.1 - 0.19 11.2 0.1 28 4.2 0.0 2.5 2 0 0 2 2 2 0 AAA domain Proteasome_A_N PF10584.4 KLO19718.1 - 0.44 9.9 5.7 21 4.5 0.5 3.6 3 0 0 3 3 3 0 Proteasome subunit A N-terminal signature WD40 PF00400.27 KLO19719.1 - 3.6e-44 147.1 41.6 7.2e-12 44.7 2.6 9.7 11 0 0 11 11 11 6 WD domain, G-beta repeat NACHT PF05729.7 KLO19719.1 - 7.8e-06 25.6 0.0 5e-05 23.0 0.0 2.2 1 1 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 KLO19719.1 - 4.7e-05 23.4 0.0 0.00014 21.9 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain AAA_19 PF13245.1 KLO19719.1 - 0.00091 18.9 0.0 0.0023 17.6 0.0 1.7 1 0 0 1 1 1 1 Part of AAA domain NB-ARC PF00931.17 KLO19719.1 - 0.023 13.5 0.0 0.043 12.6 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain AAA PF00004.24 KLO19719.1 - 0.026 14.7 0.0 0.17 12.0 0.0 2.6 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) AAA_11 PF13086.1 KLO19719.1 - 0.034 13.7 0.1 0.12 11.9 0.0 1.9 2 0 0 2 2 2 0 AAA domain Parvo_NS1 PF01057.12 KLO19719.1 - 0.039 12.8 0.0 0.077 11.8 0.0 1.4 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_22 PF13401.1 KLO19719.1 - 0.049 13.7 0.0 0.15 12.1 0.0 1.8 1 0 0 1 1 1 0 AAA domain Pkinase PF00069.20 KLO19720.1 - 2.8e-42 144.6 0.0 8.7e-24 84.0 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 KLO19720.1 - 7.6e-15 54.6 0.0 6e-10 38.6 0.0 2.5 3 0 0 3 3 3 2 Protein tyrosine kinase PrmA PF06325.8 KLO19720.1 - 0.081 12.0 0.0 0.13 11.3 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Pox_ser-thr_kin PF05445.6 KLO19720.1 - 0.4 9.4 0.0 0.6 8.8 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Pyr_redox_2 PF07992.9 KLO19722.1 - 2.2e-41 141.9 0.0 6.2e-41 140.5 0.0 2.0 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.17 KLO19722.1 - 9e-33 112.5 0.1 1.8e-32 111.6 0.1 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.22 KLO19722.1 - 1.2e-21 76.8 5.4 7.7e-18 64.6 0.4 2.7 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 KLO19722.1 - 1.6e-15 57.7 0.4 1.5e-10 41.4 0.0 2.2 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 KLO19722.1 - 1.6e-12 46.6 2.9 6.2e-06 24.9 0.0 2.9 3 0 0 3 3 3 2 HI0933-like protein FAD_oxidored PF12831.2 KLO19722.1 - 3e-12 46.3 0.6 4e-11 42.6 0.0 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 KLO19722.1 - 3.8e-08 32.5 0.4 5.4e-06 25.5 0.0 2.5 2 0 0 2 2 2 1 FAD binding domain K_oxygenase PF13434.1 KLO19722.1 - 6.6e-07 28.5 0.1 3.5e-06 26.1 0.0 1.9 1 1 1 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.1 KLO19722.1 - 4.2e-06 26.7 1.4 4.2e-06 26.7 0.9 1.8 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain GIDA PF01134.17 KLO19722.1 - 1.4e-05 24.2 1.9 6e-05 22.0 0.3 2.4 2 0 0 2 2 2 1 Glucose inhibited division protein A DAO PF01266.19 KLO19722.1 - 3.6e-05 22.8 7.3 0.00044 19.2 0.1 2.8 3 0 0 3 3 3 2 FAD dependent oxidoreductase Thi4 PF01946.12 KLO19722.1 - 7.2e-05 21.9 0.3 0.00017 20.7 0.2 1.6 1 0 0 1 1 1 1 Thi4 family AlaDh_PNT_C PF01262.16 KLO19722.1 - 0.0027 17.2 0.8 0.34 10.4 0.1 2.4 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_7 PF13241.1 KLO19722.1 - 0.0039 17.4 0.2 0.77 10.0 0.0 2.6 2 0 0 2 2 2 1 Putative NAD(P)-binding 3HCDH_N PF02737.13 KLO19722.1 - 0.0048 16.5 3.8 0.076 12.6 0.1 2.4 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_binding_3 PF01494.14 KLO19722.1 - 0.0086 15.1 6.6 0.33 9.9 0.1 2.7 2 1 0 3 3 3 2 FAD binding domain NAD_Gly3P_dh_N PF01210.18 KLO19722.1 - 0.018 14.7 0.3 0.77 9.4 0.0 2.3 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_binding_9 PF13454.1 KLO19722.1 - 0.035 13.8 4.7 0.13 12.0 0.1 3.1 3 0 0 3 3 3 0 FAD-NAD(P)-binding 2-Hacid_dh_C PF02826.14 KLO19722.1 - 0.076 12.1 0.6 1.3 8.1 0.0 2.7 3 0 0 3 3 3 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain WD40 PF00400.27 KLO19723.1 - 1.9e-28 97.2 12.5 3.7e-07 29.7 0.1 7.6 8 0 0 8 8 8 5 WD domain, G-beta repeat NACHT PF05729.7 KLO19723.1 - 8.2e-09 35.3 0.1 1e-07 31.7 0.0 2.7 2 1 0 2 2 2 1 NACHT domain PQQ_3 PF13570.1 KLO19723.1 - 0.049 13.9 0.3 2 8.8 0.0 3.4 4 0 0 4 4 4 0 PQQ-like domain Calcipressin PF04847.7 KLO19727.1 - 3.3e-31 108.2 0.2 2.2e-29 102.3 0.1 2.1 1 1 0 1 1 1 1 Calcipressin MIF4G PF02854.14 KLO19730.1 - 1.9e-30 105.8 3.3 1.8e-29 102.6 0.1 2.6 2 1 0 2 2 2 2 MIF4G domain MA3 PF02847.12 KLO19730.1 - 3.9e-24 84.5 0.3 9e-24 83.3 0.2 1.7 1 0 0 1 1 1 1 MA3 domain DUF331 PF03889.8 KLO19731.1 - 0.043 13.1 0.0 0.079 12.2 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function Mtc PF03820.12 KLO19736.1 - 0.0056 15.3 0.0 0.0087 14.7 0.0 1.2 1 0 0 1 1 1 1 Tricarboxylate carrier Col_cuticle_N PF01484.12 KLO19736.1 - 1.3 8.8 5.1 0.78 9.4 0.1 2.8 2 0 0 2 2 2 0 Nematode cuticle collagen N-terminal domain S-methyl_trans PF02574.11 KLO19738.1 - 0.05 12.8 0.0 0.094 11.9 0.0 1.5 1 0 0 1 1 1 0 Homocysteine S-methyltransferase DUF373 PF04123.8 KLO19738.1 - 0.72 8.8 4.7 1.1 8.2 3.2 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF373) Syntaphilin PF15290.1 KLO19745.1 - 0.13 11.7 2.9 0.088 12.2 1.1 1.4 1 1 0 1 1 1 0 Golgi-localised syntaxin-1-binding clamp NACHT PF05729.7 KLO19747.1 - 1.3e-17 63.9 0.1 4.2e-13 49.2 0.0 3.4 3 0 0 3 3 3 2 NACHT domain AAA_16 PF13191.1 KLO19747.1 - 6e-09 36.1 0.0 0.0011 19.0 0.0 3.3 2 1 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.1 KLO19747.1 - 1.1e-07 32.0 0.0 8.8e-05 22.6 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA PF00004.24 KLO19747.1 - 3.7e-05 23.9 0.0 0.00053 20.2 0.0 2.6 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Parvo_NS1 PF01057.12 KLO19747.1 - 0.0043 15.9 1.2 1.5 7.6 0.0 2.4 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 AAA_30 PF13604.1 KLO19747.1 - 0.0047 16.5 0.9 0.2 11.2 0.1 2.3 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 KLO19747.1 - 0.0061 17.3 0.0 0.085 13.6 0.0 2.9 2 0 0 2 2 2 1 AAA domain NB-ARC PF00931.17 KLO19747.1 - 0.0062 15.4 0.0 0.039 12.8 0.0 2.3 2 0 0 2 2 2 1 NB-ARC domain AAA_19 PF13245.1 KLO19747.1 - 0.0082 15.8 0.2 0.16 11.7 0.1 2.5 2 0 0 2 2 2 1 Part of AAA domain RNA_helicase PF00910.17 KLO19747.1 - 0.011 15.8 0.3 0.89 9.7 0.0 2.7 2 0 0 2 2 2 0 RNA helicase AAA_18 PF13238.1 KLO19747.1 - 0.013 15.7 0.0 0.13 12.5 0.0 2.7 2 0 0 2 2 2 0 AAA domain KAP_NTPase PF07693.9 KLO19747.1 - 0.021 13.8 0.0 0.82 8.5 0.0 2.4 2 0 0 2 2 2 0 KAP family P-loop domain AAA_10 PF12846.2 KLO19747.1 - 0.098 12.0 0.1 0.97 8.7 0.1 2.5 2 1 0 2 2 2 0 AAA-like domain APS_kinase PF01583.15 KLO19747.1 - 0.16 11.6 3.4 0.56 9.8 0.3 2.3 2 0 0 2 2 2 0 Adenylylsulphate kinase AAA_33 PF13671.1 KLO19747.1 - 0.18 11.6 0.4 1 9.2 0.0 2.4 3 0 0 3 3 3 0 AAA domain MobB PF03205.9 KLO19747.1 - 0.23 11.1 0.1 1.3 8.7 0.0 2.2 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B NACHT PF05729.7 KLO19749.1 - 2e-16 60.1 0.1 1.6e-11 44.1 0.0 3.3 2 1 0 2 2 2 2 NACHT domain AAA_22 PF13401.1 KLO19749.1 - 3e-09 37.0 0.0 2e-05 24.7 0.0 3.1 3 0 0 3 3 3 2 AAA domain AAA_16 PF13191.1 KLO19749.1 - 2.2e-07 31.0 6.0 0.0075 16.2 0.1 4.1 4 2 0 4 4 3 2 AAA ATPase domain Parvo_NS1 PF01057.12 KLO19749.1 - 3.8e-06 25.9 0.0 0.0023 16.8 0.0 2.5 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 NB-ARC PF00931.17 KLO19749.1 - 1.2e-05 24.3 0.0 0.016 14.0 0.0 2.7 3 0 0 3 3 3 2 NB-ARC domain Arch_ATPase PF01637.13 KLO19749.1 - 0.00077 19.2 0.0 0.057 13.1 0.0 2.5 2 0 0 2 2 2 1 Archaeal ATPase Torsin PF06309.6 KLO19749.1 - 0.00078 19.3 0.0 0.77 9.6 0.0 2.9 2 0 0 2 2 2 1 Torsin APS_kinase PF01583.15 KLO19749.1 - 0.0015 18.2 0.2 0.88 9.2 0.0 2.5 2 0 0 2 2 2 2 Adenylylsulphate kinase RNA_helicase PF00910.17 KLO19749.1 - 0.0021 18.2 0.1 0.18 12.0 0.0 2.7 2 0 0 2 2 2 1 RNA helicase AAA PF00004.24 KLO19749.1 - 0.0072 16.5 0.0 0.075 13.2 0.0 2.8 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) PSS PF03034.10 KLO19749.1 - 0.012 15.0 1.1 1.2 8.5 0.1 2.2 2 0 0 2 2 2 0 Phosphatidyl serine synthase Rad17 PF03215.10 KLO19749.1 - 0.013 14.1 0.0 0.023 13.4 0.0 1.2 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein AAA_30 PF13604.1 KLO19749.1 - 0.015 14.8 0.1 0.44 10.1 0.0 2.3 2 0 0 2 2 2 0 AAA domain PhoH PF02562.11 KLO19749.1 - 0.032 13.4 0.0 0.43 9.7 0.0 2.2 2 0 0 2 2 2 0 PhoH-like protein AAA_17 PF13207.1 KLO19749.1 - 0.071 13.9 0.1 2.5 8.9 0.0 3.3 2 1 0 2 2 2 0 AAA domain AAA_19 PF13245.1 KLO19749.1 - 0.097 12.4 0.0 0.57 9.9 0.0 2.3 2 0 0 2 2 2 0 Part of AAA domain AAA_33 PF13671.1 KLO19749.1 - 0.13 12.1 0.2 2.6 7.9 0.0 3.0 3 0 0 3 3 3 0 AAA domain AAA_PrkA PF08298.6 KLO19749.1 - 0.16 10.6 0.0 0.57 8.8 0.0 1.8 2 0 0 2 2 2 0 PrkA AAA domain ABC_tran PF00005.22 KLO19749.1 - 0.16 12.2 0.0 1.2 9.4 0.0 2.4 2 0 0 2 2 2 0 ABC transporter Abhydrolase_6 PF12697.2 KLO19751.1 - 4.2e-19 69.3 0.0 4.9e-19 69.1 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KLO19751.1 - 0.044 13.3 0.0 3.5 7.0 0.0 2.1 1 1 1 2 2 2 0 alpha/beta hydrolase fold Hydrophobin PF01185.13 KLO19752.1 - 2e-17 63.4 10.3 2.6e-17 63.0 7.1 1.2 1 0 0 1 1 1 1 Fungal hydrophobin DUF2436 PF10365.4 KLO19754.1 - 0.024 14.2 0.2 0.64 9.6 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF2436) DUF3440 PF11922.3 KLO19754.1 - 0.026 14.0 0.0 0.043 13.3 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3440) His_Phos_2 PF00328.17 KLO19760.1 - 3.3e-83 279.9 0.0 4.2e-83 279.5 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) RimK PF08443.6 KLO19760.1 - 0.00016 21.2 0.0 0.00029 20.3 0.0 1.4 1 0 0 1 1 1 1 RimK-like ATP-grasp domain Spc97_Spc98 PF04130.8 KLO19761.1 - 1.2e-113 380.3 0.0 1.8e-113 379.7 0.0 1.3 1 0 0 1 1 1 1 Spc97 / Spc98 family Mob1_phocein PF03637.12 KLO19762.1 - 1.4e-73 246.2 0.0 1.7e-73 246.0 0.0 1.0 1 0 0 1 1 1 1 Mob1/phocein family UPF0220 PF05255.6 KLO19763.1 - 1e-49 167.9 0.0 1.3e-49 167.5 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0220) DUF4077 PF13295.1 KLO19763.1 - 0.045 13.4 0.3 0.061 13.0 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4077) BPD_transp_2 PF02653.11 KLO19763.1 - 0.06 12.3 3.3 0.043 12.7 0.9 1.6 2 0 0 2 2 2 0 Branched-chain amino acid transport system / permease component GTP_EFTU PF00009.22 KLO19765.1 - 8.8e-44 149.1 0.3 1.4e-43 148.5 0.0 1.6 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 KLO19765.1 - 1.1e-23 83.3 0.1 2.8e-23 81.9 0.1 1.8 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 KLO19765.1 - 6.3e-10 39.0 1.0 6.3e-10 39.0 0.7 1.9 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 KLO19765.1 - 0.00016 21.6 0.0 0.00061 19.7 0.0 2.0 1 1 0 1 1 1 1 50S ribosome-binding GTPase DUF605 PF04652.11 KLO19765.1 - 0.77 9.0 13.5 1 8.6 9.3 1.2 1 0 0 1 1 1 0 Vta1 like SH3_9 PF14604.1 KLO19766.1 - 5.6e-42 141.1 8.9 2.4e-14 52.6 0.1 4.2 4 0 0 4 4 4 3 Variant SH3 domain SH3_1 PF00018.23 KLO19766.1 - 4.7e-41 137.9 7.8 1.2e-14 53.3 0.1 4.3 4 0 0 4 4 4 3 SH3 domain SHD1 PF03983.7 KLO19766.1 - 4.3e-28 96.7 0.0 9.3e-28 95.6 0.0 1.6 1 0 0 1 1 1 1 SLA1 homology domain 1, SHD1 SH3_2 PF07653.12 KLO19766.1 - 1.6e-27 94.7 0.2 1.4e-07 30.8 0.0 4.7 4 0 0 4 4 4 4 Variant SH3 domain SH3_3 PF08239.6 KLO19766.1 - 1.4e-08 34.7 5.3 0.0007 19.7 0.2 3.6 3 0 0 3 3 3 2 Bacterial SH3 domain SAM_1 PF00536.25 KLO19766.1 - 0.031 14.4 0.0 0.057 13.6 0.0 1.3 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) TnpW PF14202.1 KLO19766.1 - 0.096 12.2 0.0 0.18 11.4 0.0 1.4 1 0 0 1 1 1 0 Transposon-encoded protein TnpW Sec7 PF01369.15 KLO19767.1 - 3.9e-67 225.6 0.2 1.9e-66 223.3 0.2 2.2 1 0 0 1 1 1 1 Sec7 domain Sec7_N PF12783.2 KLO19767.1 - 2e-55 186.8 4.2 2e-55 186.8 2.9 2.9 3 1 0 3 3 3 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF1981 PF09324.5 KLO19767.1 - 2.6e-32 110.1 6.1 9.6e-31 105.1 0.2 5.1 6 0 0 6 6 6 1 Domain of unknown function (DUF1981) HEAT PF02985.17 KLO19767.1 - 0.042 13.9 0.0 17 5.8 0.0 4.0 3 0 0 3 3 3 0 HEAT repeat DS PF01916.12 KLO19768.1 - 7e-139 462.0 0.0 8.1e-139 461.8 0.0 1.0 1 0 0 1 1 1 1 Deoxyhypusine synthase Sedlin_N PF04628.8 KLO19769.1 - 3e-23 82.1 0.0 3.5e-23 81.9 0.0 1.1 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region DUF3909 PF13077.1 KLO19769.1 - 0.059 13.2 0.1 0.19 11.5 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3909) NUDIX PF00293.23 KLO19770.1 - 5e-10 39.1 0.0 6.6e-10 38.7 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain PGG PF13962.1 KLO19771.1 - 1.4 8.5 9.5 0.067 12.8 0.6 2.7 2 1 1 3 3 3 0 Domain of unknown function Nop PF01798.13 KLO19772.1 - 4.4e-59 198.0 0.5 8.2e-59 197.2 0.4 1.5 1 0 0 1 1 1 1 Putative snoRNA binding domain NOSIC PF08060.8 KLO19772.1 - 7e-26 89.7 0.0 1.2e-25 89.0 0.0 1.4 1 0 0 1 1 1 1 NOSIC (NUC001) domain NOP5NT PF08156.8 KLO19772.1 - 3.8e-18 65.3 0.3 3.8e-18 65.3 0.2 2.5 2 0 0 2 2 2 1 NOP5NT (NUC127) domain adh_short PF00106.20 KLO19773.1 - 3e-07 30.5 0.1 0.11 12.3 0.0 3.4 3 0 0 3 3 3 2 short chain dehydrogenase SH3_7 PF12914.2 KLO19773.1 - 0.0095 15.6 0.0 0.027 14.2 0.0 1.7 1 0 0 1 1 1 1 SH3 domain of SH3b2 type Epimerase PF01370.16 KLO19773.1 - 0.02 14.3 1.5 4.2 6.7 0.1 2.8 3 0 0 3 3 3 0 NAD dependent epimerase/dehydratase family KR PF08659.5 KLO19773.1 - 0.021 14.5 0.4 1.9 8.1 0.0 2.4 2 0 0 2 2 2 0 KR domain LcrG PF07216.7 KLO19773.1 - 0.078 13.0 0.0 0.15 12.0 0.0 1.4 1 0 0 1 1 1 0 LcrG protein Peptidase_M20 PF01546.23 KLO19774.1 - 1.1e-27 96.7 0.0 1.4e-27 96.3 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 KLO19774.1 - 0.00046 19.8 0.0 0.00077 19.1 0.0 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.12 KLO19774.1 - 0.001 18.8 0.0 0.0017 18.1 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M28 Herpes_gE PF02480.11 KLO19775.1 - 0.028 12.6 0.0 0.45 8.7 0.0 2.0 2 0 0 2 2 2 0 Alphaherpesvirus glycoprotein E AJAP1_PANP_C PF15298.1 KLO19775.1 - 0.09 12.6 0.1 0.22 11.3 0.0 1.7 1 1 1 2 2 2 0 AJAP1/PANP C-terminus OppC_N PF12911.2 KLO19775.1 - 0.22 10.9 0.0 0.22 10.9 0.0 1.9 2 0 0 2 2 2 0 N-terminal TM domain of oligopeptide transport permease C GFO_IDH_MocA PF01408.17 KLO19776.1 - 8.2e-22 77.9 0.7 1.3e-21 77.2 0.5 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 KLO19776.1 - 0.0025 17.6 0.0 0.014 15.2 0.0 2.1 2 0 0 2 2 2 1 Oxidoreductase family, C-terminal alpha/beta domain MukB PF04310.7 KLO19776.1 - 0.0052 16.1 0.0 0.011 15.0 0.0 1.5 1 0 0 1 1 1 1 MukB N-terminal F420_oxidored PF03807.12 KLO19776.1 - 0.044 14.2 0.0 0.11 12.9 0.0 1.7 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent TrkA_N PF02254.13 KLO19776.1 - 0.045 13.7 0.0 0.083 12.8 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain Sclerostin PF05463.6 KLO19776.1 - 0.049 13.1 0.0 0.082 12.3 0.0 1.3 1 0 0 1 1 1 0 Sclerostin (SOST) Peptidase_M28 PF04389.12 KLO19777.1 - 7.9e-15 55.0 0.0 2.6e-14 53.3 0.0 1.8 1 1 0 1 1 1 1 Peptidase family M28 TFR_dimer PF04253.10 KLO19777.1 - 2.3e-13 49.7 0.0 1.1e-12 47.6 0.0 2.0 2 0 0 2 2 2 1 Transferrin receptor-like dimerisation domain PA PF02225.17 KLO19777.1 - 2e-08 33.8 0.0 4.7e-08 32.6 0.0 1.6 1 0 0 1 1 1 1 PA domain Nicastrin PF05450.10 KLO19777.1 - 0.0041 16.4 0.2 0.01 15.0 0.0 1.7 2 0 0 2 2 2 1 Nicastrin Peptidase_M20 PF01546.23 KLO19777.1 - 0.034 13.6 0.0 0.072 12.5 0.0 1.6 1 1 0 1 1 1 0 Peptidase family M20/M25/M40 Mis14 PF08641.7 KLO19778.1 - 0.0016 18.5 9.9 0.0016 18.5 6.8 1.9 1 1 1 2 2 2 1 Kinetochore protein Mis14 like Iron_traffic PF04362.9 KLO19778.1 - 0.007 15.7 0.3 0.016 14.6 0.2 1.6 1 0 0 1 1 1 1 Bacterial Fe(2+) trafficking L_lactis_ph-MCP PF06673.6 KLO19778.1 - 0.024 13.4 1.1 0.034 12.9 0.8 1.3 1 0 0 1 1 1 0 Lactococcus lactis bacteriophage major capsid protein F-box-like PF12937.2 KLO19779.1 - 1.8e-06 27.5 1.1 9.6e-06 25.2 0.0 2.8 2 0 0 2 2 2 1 F-box-like RCC1 PF00415.13 KLO19781.1 - 2.5e-64 213.2 7.0 8.8e-11 41.8 0.2 7.5 7 0 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 KLO19781.1 - 5.6e-32 108.6 43.2 4.1e-06 26.2 1.1 8.2 8 0 0 8 8 8 8 Regulator of chromosome condensation (RCC1) repeat DIOX_N PF14226.1 KLO19782.1 - 5.5e-26 91.3 0.1 9.6e-26 90.6 0.1 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 KLO19782.1 - 1.6e-18 66.8 0.0 2.8e-18 66.0 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Alpha_kinase PF02816.13 KLO19783.1 - 1e-18 67.6 0.0 1.6e-18 67.0 0.0 1.3 1 0 0 1 1 1 1 Alpha-kinase family DUF3413 PF11893.3 KLO19783.1 - 0.041 12.7 0.0 0.062 12.1 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3413) WTX PF09422.5 KLO19786.1 - 0.028 13.3 2.0 0.041 12.8 1.4 1.2 1 0 0 1 1 1 0 WTX protein GPI-anchored PF10342.4 KLO19788.1 - 1.2e-11 44.9 3.4 1.2e-11 44.9 2.4 1.5 2 0 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family PGAP1 PF07819.8 KLO19789.1 - 3.4e-54 183.7 0.0 4.7e-54 183.3 0.0 1.2 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_5 PF12695.2 KLO19789.1 - 3e-09 36.7 0.0 6.1e-09 35.7 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KLO19789.1 - 1e-06 28.8 0.0 2e-06 27.8 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KLO19789.1 - 0.014 14.9 0.0 0.023 14.2 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold Lipase_3 PF01764.20 KLO19789.1 - 0.018 14.6 0.0 0.034 13.7 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) DUF2305 PF10230.4 KLO19789.1 - 0.047 13.0 0.0 0.094 12.1 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2305) Snf7 PF03357.16 KLO19790.1 - 1.3e-43 148.3 15.1 1.6e-43 148.0 10.5 1.1 1 0 0 1 1 1 1 Snf7 NPV_P10 PF05531.7 KLO19790.1 - 0.00036 20.7 2.6 1.3 9.3 0.9 3.3 2 1 0 2 2 2 1 Nucleopolyhedrovirus P10 protein DUF3584 PF12128.3 KLO19790.1 - 0.00047 17.6 10.8 0.00055 17.4 7.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) NuA4 PF09340.5 KLO19790.1 - 0.0032 17.0 2.7 0.005 16.4 0.9 2.0 1 1 1 2 2 2 1 Histone acetyltransferase subunit NuA4 Mnd1 PF03962.10 KLO19790.1 - 0.01 15.5 12.0 0.061 12.9 8.4 2.1 1 1 0 1 1 1 0 Mnd1 family PspA_IM30 PF04012.7 KLO19790.1 - 0.017 14.5 14.2 0.017 14.4 8.7 1.7 2 0 0 2 2 2 0 PspA/IM30 family DUF342 PF03961.8 KLO19790.1 - 0.028 12.8 9.0 0.016 13.6 4.2 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF342) DUF3091 PF11291.3 KLO19790.1 - 0.075 12.9 3.5 0.1 12.5 0.2 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF3091) Prefoldin_2 PF01920.15 KLO19790.1 - 0.092 12.5 12.5 10 5.9 0.0 3.3 2 1 1 3 3 3 0 Prefoldin subunit DUF464 PF04327.7 KLO19790.1 - 0.15 12.3 2.5 0.16 12.1 0.7 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF464) TcdB_N PF12918.2 KLO19790.1 - 0.16 12.0 1.5 0.85 9.7 0.1 2.7 1 1 0 2 2 2 0 TcdB toxin N-terminal helical domain FlxA PF14282.1 KLO19790.1 - 0.22 11.5 16.5 0.05 13.5 7.2 2.4 1 1 1 2 2 2 0 FlxA-like protein AAA_13 PF13166.1 KLO19790.1 - 0.23 9.8 7.3 0.29 9.5 5.1 1.2 1 0 0 1 1 1 0 AAA domain Vps5 PF09325.5 KLO19790.1 - 0.79 8.9 10.0 1.1 8.4 6.1 1.7 1 1 0 1 1 1 0 Vps5 C terminal like Vps51 PF08700.6 KLO19790.1 - 0.84 9.5 6.2 4.6 7.1 0.0 3.7 2 1 2 4 4 4 0 Vps51/Vps67 TBPIP PF07106.8 KLO19790.1 - 1.3 8.5 11.9 0.23 10.9 3.9 2.2 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DUF972 PF06156.8 KLO19790.1 - 1.9 8.8 10.6 6.5e+02 0.7 7.3 2.9 1 1 0 1 1 1 0 Protein of unknown function (DUF972) Prefoldin PF02996.12 KLO19790.1 - 2.5 7.7 16.1 1 9.0 0.1 3.7 3 1 0 4 4 4 0 Prefoldin subunit DUF2203 PF09969.4 KLO19790.1 - 3 8.0 5.2 10 6.3 0.9 2.3 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) V_ATPase_I PF01496.14 KLO19790.1 - 6.1 4.5 7.9 10 3.8 5.5 1.5 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF4407 PF14362.1 KLO19790.1 - 6.6 5.5 11.9 0.78 8.6 4.7 1.7 1 1 0 2 2 2 0 Domain of unknown function (DUF4407) DUF1644 PF07800.7 KLO19791.1 - 0.0092 15.8 1.4 0.052 13.3 0.3 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF1644) zf-TRAF PF02176.13 KLO19791.1 - 0.99 9.8 7.7 5.6 7.4 0.0 2.6 3 0 0 3 3 3 0 TRAF-type zinc finger F-box-like PF12937.2 KLO19792.1 - 3.6e-08 33.0 0.0 1.8e-07 30.7 0.0 2.3 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KLO19792.1 - 0.53 10.0 5.2 4.6 7.0 0.2 3.1 3 0 0 3 3 3 0 F-box domain CTNNBL PF08216.6 KLO19793.1 - 7.5e-29 99.4 0.1 2.7e-28 97.6 0.0 2.0 2 0 0 2 2 2 1 Catenin-beta-like, Arm-motif containing nuclear Arm PF00514.18 KLO19793.1 - 0.03 14.1 0.7 1.2 9.1 0.0 3.4 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat DUF4303 PF14136.1 KLO19793.1 - 0.059 13.0 0.5 0.24 11.0 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4303) Amidohydro_2 PF04909.9 KLO19795.1 - 1.7e-29 103.2 0.9 3.2e-29 102.3 0.7 1.5 1 1 0 1 1 1 1 Amidohydrolase TatD_DNase PF01026.16 KLO19795.1 - 0.0031 16.7 0.0 0.0077 15.4 0.0 1.6 2 0 0 2 2 2 1 TatD related DNase QRPTase_C PF01729.14 KLO19796.1 - 2.1e-50 170.5 0.1 2.7e-50 170.1 0.1 1.2 1 0 0 1 1 1 1 Quinolinate phosphoribosyl transferase, C-terminal domain QRPTase_N PF02749.11 KLO19796.1 - 1e-21 76.5 0.0 2.4e-21 75.3 0.0 1.6 1 0 0 1 1 1 1 Quinolinate phosphoribosyl transferase, N-terminal domain GMC_oxred_C PF05199.8 KLO19799.1 - 3.6e-15 56.5 0.0 8.1e-15 55.3 0.0 1.6 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_N PF00732.14 KLO19799.1 - 0.00017 20.8 0.0 0.00099 18.3 0.0 2.0 2 0 0 2 2 2 1 GMC oxidoreductase RRM_1 PF00076.17 KLO19800.1 - 2.1e-16 59.3 0.0 3.2e-16 58.7 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KLO19800.1 - 2.5e-10 40.1 0.0 4.8e-10 39.2 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KLO19800.1 - 0.00089 19.0 0.0 0.0014 18.4 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCHC_4 PF14392.1 KLO19801.1 - 0.23 11.1 3.2 2.6 7.7 0.0 2.3 2 0 0 2 2 2 0 Zinc knuckle BTB_2 PF02214.17 KLO19802.1 - 0.097 12.8 0.0 0.87 9.8 0.0 2.3 2 0 0 2 2 2 0 BTB/POZ domain BiPBP_C PF06832.7 KLO19804.1 - 0.012 15.4 0.0 0.019 14.8 0.0 1.3 1 0 0 1 1 1 0 Penicillin-Binding Protein C-terminus Family DUF1727 PF08353.5 KLO19804.1 - 0.04 13.5 1.2 0.87 9.2 0.8 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF1727) Ifi-6-16 PF06140.8 KLO19805.1 - 0.51 10.1 15.6 0.9 9.3 10.8 1.4 1 0 0 1 1 1 0 Interferon-induced 6-16 family Pkinase PF00069.20 KLO19806.1 - 3.7e-40 137.7 0.0 5.8e-40 137.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KLO19806.1 - 4.9e-37 127.4 0.0 7.1e-37 126.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.17 KLO19806.1 - 0.00036 19.9 0.1 0.00088 18.6 0.0 1.6 2 0 0 2 2 2 1 RIO1 family APH PF01636.18 KLO19806.1 - 0.00053 19.8 0.0 0.0016 18.1 0.0 1.8 2 1 0 2 2 2 1 Phosphotransferase enzyme family Cu_amine_oxid PF01179.15 KLO19806.1 - 0.07 11.8 0.1 0.1 11.2 0.1 1.1 1 0 0 1 1 1 0 Copper amine oxidase, enzyme domain Pkinase_Tyr PF07714.12 KLO19808.1 - 8.9e-36 123.2 0.0 1.3e-35 122.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 KLO19808.1 - 4.2e-34 117.8 0.0 5.8e-34 117.4 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.1 KLO19808.1 - 0.0027 16.7 0.0 0.0041 16.1 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pkinase PF00069.20 KLO19810.1 - 1.1e-42 146.0 0.0 1.5e-42 145.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KLO19810.1 - 2e-42 145.0 0.0 2.8e-42 144.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KLO19810.1 - 3.2e-07 29.5 0.0 4.6e-07 29.0 0.0 1.2 1 0 0 1 1 1 1 Kinase-like FTR1 PF03239.9 KLO19811.1 - 3.1e-59 200.4 3.9 4e-59 200.0 2.7 1.1 1 0 0 1 1 1 1 Iron permease FTR1 family DUF2852 PF11014.3 KLO19811.1 - 0.033 14.1 0.0 0.068 13.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2852) Vma12 PF11712.3 KLO19811.1 - 0.25 11.0 1.2 0.94 9.1 0.0 2.4 2 0 0 2 2 2 0 Endoplasmic reticulum-based factor for assembly of V-ATPase RseC_MucC PF04246.7 KLO19811.1 - 5.2 6.6 11.5 3 7.4 1.5 2.9 2 0 0 2 2 2 0 Positive regulator of sigma(E), RseC/MucC Ribosomal_L18p PF00861.17 KLO19812.1 - 3.8e-42 143.2 1.2 4.8e-42 142.9 0.1 1.7 2 0 0 2 2 2 1 Ribosomal L18p/L5e family Ribosomal_L18_c PF14204.1 KLO19812.1 - 5.5e-35 119.8 5.9 5.5e-35 119.8 4.1 1.8 2 0 0 2 2 2 1 Ribosomal L18 C-terminal region MtrA PF04208.9 KLO19812.1 - 0.031 13.7 0.0 0.061 12.7 0.0 1.4 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, subunit A Thr_synth_N PF14821.1 KLO19812.1 - 0.13 12.3 0.4 8.4 6.4 0.0 2.6 2 1 0 2 2 2 0 Threonine synthase N terminus DEAD PF00270.24 KLO19814.1 - 3.8e-47 159.9 0.0 4.1e-46 156.5 0.0 2.3 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KLO19814.1 - 6.9e-23 80.3 0.1 2.7e-22 78.3 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain SNF2_N PF00176.18 KLO19814.1 - 0.0068 15.2 0.0 0.013 14.3 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain ResIII PF04851.10 KLO19814.1 - 0.029 14.1 0.0 0.11 12.3 0.0 2.0 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit MFS_1 PF07690.11 KLO19815.1 - 4.2e-45 153.9 38.2 4.2e-45 153.9 26.5 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 KLO19815.1 - 5.4e-13 48.3 25.3 8.5e-13 47.6 17.5 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_3 PF05977.8 KLO19815.1 - 0.00018 19.8 8.3 0.00028 19.1 5.7 1.2 1 0 0 1 1 1 1 Transmembrane secretion effector Nsp1_C PF05064.8 KLO19816.1 - 7.7e-30 102.9 0.9 1.6e-29 101.8 0.1 1.9 3 0 0 3 3 3 1 Nsp1-like C-terminal region Nucleoporin_FG PF13634.1 KLO19816.1 - 1.1e-22 80.3 147.0 4.1e-12 46.3 23.8 4.7 1 1 2 4 4 4 3 Nucleoporin FG repeat region DUF3584 PF12128.3 KLO19816.1 - 0.002 15.5 2.2 0.0025 15.2 1.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) NPV_P10 PF05531.7 KLO19816.1 - 0.0025 18.0 1.8 2 8.7 0.0 3.1 2 1 1 3 3 3 2 Nucleopolyhedrovirus P10 protein Gene66 PF02053.10 KLO19816.1 - 0.055 12.8 0.0 0.098 12.0 0.0 1.3 1 0 0 1 1 1 0 Gene 66 (IR5) protein Spc7 PF08317.6 KLO19816.1 - 0.059 12.0 1.0 0.085 11.4 0.7 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein Baculo_PEP_C PF04513.7 KLO19816.1 - 0.25 11.1 3.5 0.2 11.4 0.3 2.1 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Laminin_II PF06009.7 KLO19816.1 - 0.28 10.9 3.8 0.48 10.1 0.1 2.6 2 1 1 3 3 3 0 Laminin Domain II CorA PF01544.13 KLO19816.1 - 0.93 8.4 5.3 1.6 7.6 0.3 2.2 1 1 1 2 2 2 0 CorA-like Mg2+ transporter protein CENP-Q PF13094.1 KLO19816.1 - 1.9 8.5 6.7 18 5.3 4.7 2.2 1 1 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit Syntaxin-6_N PF09177.6 KLO19816.1 - 3.3 8.1 6.2 3.3 8.1 1.3 2.6 1 1 2 3 3 3 0 Syntaxin 6, N-terminal V_ATPase_I PF01496.14 KLO19816.1 - 6 4.5 4.5 18 2.9 0.2 1.9 1 1 0 2 2 2 0 V-type ATPase 116kDa subunit family NAD_binding_6 PF08030.7 KLO19817.1 - 6.4e-19 68.3 0.0 1.1e-18 67.6 0.0 1.4 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.7 KLO19817.1 - 3.7e-17 62.1 0.0 7e-17 61.2 0.0 1.4 1 0 0 1 1 1 1 FAD-binding domain Ferric_reduct PF01794.14 KLO19817.1 - 4.1e-11 43.0 10.1 4.1e-11 43.0 7.0 2.2 3 0 0 3 3 3 1 Ferric reductase like transmembrane component Aminotran_1_2 PF00155.16 KLO19818.1 - 4.9e-63 213.2 0.0 5.6e-63 213.0 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.15 KLO19818.1 - 9.2e-05 20.8 0.0 0.0002 19.7 0.0 1.4 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.12 KLO19818.1 - 0.0003 19.9 0.0 0.00047 19.3 0.0 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Beta_elim_lyase PF01212.16 KLO19818.1 - 0.001 18.3 0.0 0.0016 17.6 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.14 KLO19818.1 - 0.0025 16.5 0.0 0.084 11.6 0.0 2.1 2 0 0 2 2 2 1 Aminotransferase class-V Sec63 PF02889.11 KLO19819.1 - 3.4e-81 272.9 0.0 4.8e-81 272.4 0.0 1.2 1 0 0 1 1 1 1 Sec63 Brl domain DEAD PF00270.24 KLO19819.1 - 6.1e-37 126.7 0.0 5.4e-29 100.8 0.3 3.8 4 0 0 4 4 4 2 DEAD/DEAH box helicase ResIII PF04851.10 KLO19819.1 - 6e-09 35.9 0.0 3e-08 33.6 0.0 2.1 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_22 PF13401.1 KLO19819.1 - 4.5e-07 30.0 0.2 0.0026 17.9 0.1 3.7 2 1 1 3 3 3 2 AAA domain Helicase_C PF00271.26 KLO19819.1 - 6.5e-07 29.1 0.0 2.2e-06 27.4 0.0 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain IstB_IS21 PF01695.12 KLO19819.1 - 0.0025 17.2 0.1 5.5 6.3 0.0 3.4 3 0 0 3 3 3 1 IstB-like ATP binding protein AAA_23 PF13476.1 KLO19819.1 - 0.0027 18.0 0.3 0.14 12.4 0.0 2.8 3 0 0 3 3 3 1 AAA domain AAA_10 PF12846.2 KLO19819.1 - 0.0029 17.1 0.0 1.4 8.3 0.0 3.2 2 1 1 3 3 3 1 AAA-like domain AAA_25 PF13481.1 KLO19819.1 - 0.004 16.5 0.0 11 5.4 0.0 3.7 3 0 0 3 3 3 1 AAA domain AAA_16 PF13191.1 KLO19819.1 - 0.0057 16.6 0.2 5.1 7.0 0.0 3.5 3 1 0 3 3 3 1 AAA ATPase domain SNF2_N PF00176.18 KLO19819.1 - 0.0068 15.2 0.0 0.011 14.5 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain AAA_19 PF13245.1 KLO19819.1 - 0.01 15.5 0.0 1 9.1 0.0 3.1 2 0 0 2 2 2 0 Part of AAA domain AAA_29 PF13555.1 KLO19819.1 - 0.026 14.0 0.0 0.28 10.7 0.0 2.4 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_33 PF13671.1 KLO19819.1 - 0.046 13.5 0.9 2.7 7.8 0.1 3.4 3 0 0 3 3 3 0 AAA domain DUF106 PF01956.11 KLO19820.1 - 2.1e-53 180.3 0.0 2.6e-53 180.0 0.0 1.1 1 0 0 1 1 1 1 Integral membrane protein DUF106 EF-hand_1 PF00036.27 KLO19821.1 - 2e-21 73.5 12.6 6.7e-07 28.1 0.0 4.8 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.1 KLO19821.1 - 5.4e-18 64.8 7.3 2.4e-11 43.5 0.1 3.4 1 1 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 KLO19821.1 - 4e-15 54.2 7.0 8.4e-05 22.1 0.9 4.9 5 0 0 5 5 5 4 EF-hand domain EF-hand_4 PF12763.2 KLO19821.1 - 1.1e-08 34.7 9.2 0.0061 16.2 0.1 4.2 1 1 2 4 4 4 3 Cytoskeletal-regulatory complex EF hand EF-hand_8 PF13833.1 KLO19821.1 - 2.2e-08 33.5 12.9 0.0019 17.7 1.1 4.4 3 1 1 4 4 4 4 EF-hand domain pair EF-hand_5 PF13202.1 KLO19821.1 - 3.9e-07 29.1 12.2 0.082 12.2 1.2 5.0 5 0 0 5 5 5 3 EF hand SPARC_Ca_bdg PF10591.4 KLO19821.1 - 0.017 15.1 4.6 1.6 8.7 0.1 3.3 2 2 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region WD40 PF00400.27 KLO19823.1 - 0.00017 21.3 1.4 0.015 15.1 0.1 3.0 2 0 0 2 2 2 2 WD domain, G-beta repeat DUF1513 PF07433.6 KLO19823.1 - 0.017 14.0 0.0 0.035 13.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1513) DUF3885 PF13021.1 KLO19824.1 - 0.27 10.9 2.3 12 5.7 0.2 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF3885) F-box-like PF12937.2 KLO19825.1 - 0.0053 16.4 0.3 0.3 10.8 0.0 2.8 2 0 0 2 2 2 2 F-box-like ATE_C PF04377.10 KLO19826.1 - 3.8e-42 143.3 0.7 6.7e-42 142.5 0.5 1.4 1 0 0 1 1 1 1 Arginine-tRNA-protein transferase, C terminus ATE_N PF04376.8 KLO19826.1 - 7.7e-26 89.7 4.3 1.4e-25 88.8 3.0 1.4 1 0 0 1 1 1 1 Arginine-tRNA-protein transferase, N terminus DUF1129 PF06570.6 KLO19827.1 - 1.1 8.5 10.6 0.42 9.8 5.7 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1129) EF-hand_1 PF00036.27 KLO19828.1 - 1.2e-14 52.4 1.6 4.6e-06 25.5 0.1 3.8 4 0 0 4 4 4 2 EF hand EF-hand_5 PF13202.1 KLO19828.1 - 4.6e-12 44.6 0.6 1.2e-06 27.5 0.3 3.3 3 0 0 3 3 3 2 EF hand EF-hand_7 PF13499.1 KLO19828.1 - 6.8e-11 42.1 2.4 0.00023 21.2 0.1 3.5 2 2 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 KLO19828.1 - 1.2e-10 40.2 0.3 6.9e-05 22.3 0.0 3.8 4 1 0 4 4 4 2 EF-hand domain EF-hand_8 PF13833.1 KLO19828.1 - 3.8e-06 26.4 3.0 6.5e-05 22.4 0.1 3.1 3 1 0 3 3 3 1 EF-hand domain pair SPARC_Ca_bdg PF10591.4 KLO19828.1 - 0.00078 19.4 0.1 0.29 11.1 0.0 2.4 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.2 KLO19828.1 - 0.001 18.7 0.3 0.071 12.8 0.0 2.3 1 1 1 2 2 2 1 Cytoskeletal-regulatory complex EF hand DUF1218 PF06749.7 KLO19829.1 - 7.2 7.1 10.0 0.24 11.8 0.8 2.6 1 1 1 3 3 3 0 Protein of unknown function (DUF1218) Multi_Drug_Res PF00893.14 KLO19829.1 - 7.5 7.0 8.9 0.47 10.9 0.9 2.3 2 1 0 2 2 2 0 Small Multidrug Resistance protein ATE_C PF04377.10 KLO19830.1 - 1.2e-38 132.0 3.8 2.3e-38 131.1 2.6 1.4 1 0 0 1 1 1 1 Arginine-tRNA-protein transferase, C terminus ATE_N PF04376.8 KLO19830.1 - 1.8e-22 78.9 4.1 3.1e-22 78.1 2.9 1.4 1 0 0 1 1 1 1 Arginine-tRNA-protein transferase, N terminus Sugar_tr PF00083.19 KLO19831.1 - 1.7e-106 356.5 25.0 2.1e-106 356.2 17.3 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KLO19831.1 - 1.2e-21 76.8 40.2 6.6e-16 57.9 9.3 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 KLO19831.1 - 7e-06 24.6 5.9 4.3e-05 22.1 1.3 2.9 4 0 0 4 4 4 2 MFS/sugar transport protein DUF1228 PF06779.9 KLO19831.1 - 3.5e-05 23.7 2.6 0.13 12.3 0.3 2.9 2 0 0 2 2 2 2 Protein of unknown function (DUF1228) NYN PF01936.13 KLO19832.1 - 7.2e-17 62.0 0.0 2e-16 60.5 0.0 1.7 2 0 0 2 2 2 1 NYN domain IstB_IS21_ATP PF08483.6 KLO19832.1 - 0.011 15.4 0.3 4 7.2 0.1 2.8 2 0 0 2 2 2 0 IstB-like ATP binding N-terminal Peptidase_S24 PF00717.18 KLO19833.1 - 2.9e-08 33.2 0.1 7e-08 32.0 0.0 1.7 1 1 0 1 1 1 1 Peptidase S24-like Peptidase_S26 PF10502.4 KLO19833.1 - 0.032 13.7 0.0 5.2 6.6 0.0 2.5 1 1 1 2 2 2 0 Signal peptidase, peptidase S26 BAP PF06639.6 KLO19834.1 - 0.11 12.2 0.4 0.34 10.6 0.3 1.8 1 0 0 1 1 1 0 Basal layer antifungal peptide (BAP) Nup88 PF10168.4 KLO19835.1 - 1.3e-21 76.2 1.6 2.2e-09 35.7 4.3 3.2 2 1 0 2 2 2 2 Nuclear pore component Flg_bbr_C PF06429.8 KLO19835.1 - 0.14 12.0 0.1 0.71 9.8 0.0 2.1 2 0 0 2 2 2 0 Flagellar basal body rod FlgEFG protein C-terminal DUF4407 PF14362.1 KLO19835.1 - 0.19 10.6 2.8 2.8 6.7 0.3 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) Nup54 PF13874.1 KLO19835.1 - 1.1 8.9 7.4 0.91 9.1 3.2 2.1 1 1 1 2 2 2 0 Nucleoporin complex subunit 54 Proteasome PF00227.21 KLO19836.1 - 2.5e-45 154.0 0.0 3.1e-45 153.8 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 KLO19836.1 - 5.9e-13 47.8 0.1 1.1e-12 47.0 0.1 1.5 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Ribosomal_L18e PF00828.14 KLO19838.1 - 1e-20 74.3 0.1 1.6e-20 73.7 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L18e/L15 SUR7 PF06687.7 KLO19839.1 - 1.8e-14 53.8 11.4 1.6e-11 44.1 3.1 2.0 2 0 0 2 2 2 2 SUR7/PalI family Claudin_2 PF13903.1 KLO19839.1 - 0.0036 16.9 4.9 0.0036 16.9 3.4 2.1 1 1 1 2 2 2 1 PMP-22/EMP/MP20/Claudin tight junction TadE PF07811.7 KLO19839.1 - 0.29 11.0 0.1 0.29 11.0 0.1 2.4 2 0 0 2 2 2 0 TadE-like protein DUF2417 PF10329.4 KLO19839.1 - 4.6 6.5 8.4 0.35 10.2 2.3 1.6 2 0 0 2 2 2 0 Region of unknown function (DUF2417) F-box-like PF12937.2 KLO19840.1 - 3.6e-08 32.9 0.9 3.6e-08 32.9 0.6 1.9 2 0 0 2 2 2 1 F-box-like PI31_Prot_C PF08577.6 KLO19841.1 - 1.9e-14 54.0 4.3 1.9e-14 54.0 3.0 3.6 3 2 1 4 4 4 1 PI31 proteasome regulator PI31_Prot_N PF11566.3 KLO19842.1 - 2.6e-23 82.3 0.0 3.6e-23 81.8 0.0 1.1 1 0 0 1 1 1 1 PI31 proteasome regulator N-terminal PI31_Prot_C PF08577.6 KLO19842.1 - 6.2e-09 36.3 16.0 6.2e-09 36.3 11.1 3.0 2 1 0 2 2 2 1 PI31 proteasome regulator Nop25 PF09805.4 KLO19843.1 - 0.19 11.7 7.7 0.042 13.9 1.4 2.1 2 0 0 2 2 2 0 Nucleolar protein 12 (25kDa) Ank_5 PF13857.1 KLO19844.1 - 9.1e-28 95.6 0.2 1.8e-10 40.6 0.0 3.6 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.25 KLO19844.1 - 2e-25 87.2 0.7 7.7e-08 31.7 0.0 3.6 3 0 0 3 3 3 3 Ankyrin repeat Ank_4 PF13637.1 KLO19844.1 - 8.9e-24 83.4 0.3 2.8e-13 49.9 0.0 2.9 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.2 KLO19844.1 - 1.1e-23 83.3 0.0 2.9e-15 56.3 0.0 2.5 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) FYVE PF01363.16 KLO19844.1 - 1.9e-19 69.3 9.3 1.9e-19 69.3 6.5 2.5 2 1 0 2 2 1 1 FYVE zinc finger Ank_3 PF13606.1 KLO19844.1 - 4.8e-19 66.5 0.0 2.1e-05 24.2 0.0 3.6 3 0 0 3 3 3 3 Ankyrin repeat zf-RING_2 PF13639.1 KLO19844.1 - 5.3e-10 38.9 4.1 5.3e-10 38.9 2.9 3.9 4 0 0 4 4 4 1 Ring finger domain zf-rbx1 PF12678.2 KLO19844.1 - 0.00024 21.1 1.0 0.00024 21.1 0.7 2.6 3 0 0 3 3 3 1 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 KLO19844.1 - 0.00029 20.7 4.4 0.00029 20.7 3.1 3.9 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) FYVE_2 PF02318.11 KLO19844.1 - 0.0094 15.8 2.1 0.0094 15.8 1.4 2.6 2 0 0 2 2 2 1 FYVE-type zinc finger Inhibitor_I53 PF11714.3 KLO19844.1 - 0.15 12.0 0.4 0.38 10.7 0.3 1.6 1 0 0 1 1 1 0 Thrombin inhibitor Madanin Pex24p PF06398.6 KLO19844.1 - 0.29 9.9 1.0 0.53 9.0 0.7 1.4 1 0 0 1 1 1 0 Integral peroxisomal membrane peroxin HypA PF01155.14 KLO19844.1 - 1.9 8.2 7.0 1.4 8.6 1.9 2.4 2 0 0 2 2 2 0 Hydrogenase expression/synthesis hypA family BTB PF00651.26 KLO19846.1 - 3.5e-06 26.9 0.0 5.7e-06 26.2 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain Methyltransf_25 PF13649.1 KLO19847.1 - 4.4e-06 26.9 0.0 2.9e-05 24.3 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain BTB PF00651.26 KLO19848.1 - 8.2e-08 32.2 0.0 1.4e-07 31.4 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain PRP38 PF03371.10 KLO19849.1 - 3.4e-67 225.3 0.6 4.2e-67 225.0 0.4 1.1 1 0 0 1 1 1 1 PRP38 family DUF1777 PF08648.7 KLO19849.1 - 0.094 12.4 31.3 0.14 11.8 21.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1777) Ribonuc_red_sm PF00268.16 KLO19851.1 - 2.2e-119 397.6 1.8 2.7e-119 397.3 1.3 1.1 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain VMA21 PF09446.5 KLO19852.1 - 1.7e-10 40.6 6.9 2.4e-10 40.1 4.8 1.3 1 0 0 1 1 1 1 VMA21-like domain Peptidase_U4 PF03419.8 KLO19852.1 - 0.0076 15.3 0.8 0.0092 15.0 0.6 1.0 1 0 0 1 1 1 1 Sporulation factor SpoIIGA Polysacc_synt_3 PF13440.1 KLO19852.1 - 0.016 14.6 1.0 0.017 14.5 0.7 1.0 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Choline_transpo PF04515.7 KLO19852.1 - 0.062 12.0 1.9 0.072 11.8 1.3 1.0 1 0 0 1 1 1 0 Plasma-membrane choline transporter DUF2534 PF10749.4 KLO19852.1 - 0.22 11.4 1.8 0.28 11.1 1.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2534) Alg6_Alg8 PF03155.10 KLO19853.1 - 6.4e-131 437.4 28.4 3e-128 428.6 17.1 2.0 1 1 1 2 2 2 2 ALG6, ALG8 glycosyltransferase family TGS PF02824.16 KLO19854.1 - 1.7e-22 78.9 0.1 3.2e-22 78.1 0.1 1.5 1 0 0 1 1 1 1 TGS domain MMR_HSR1 PF01926.18 KLO19854.1 - 3.8e-18 65.5 0.1 1.2e-17 63.9 0.0 1.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.13 KLO19854.1 - 4.4e-09 35.7 0.1 1.4e-08 34.2 0.0 1.8 2 0 0 2 2 2 1 Ferrous iron transport protein B Dynamin_N PF00350.18 KLO19854.1 - 0.0044 16.8 0.6 2.1 8.1 0.0 2.5 1 1 1 2 2 2 2 Dynamin family ArgK PF03308.11 KLO19854.1 - 0.012 14.4 1.3 0.021 13.6 0.1 1.8 2 0 0 2 2 2 0 ArgK protein GTP_EFTU PF00009.22 KLO19854.1 - 0.044 13.2 0.3 6.8 6.0 0.1 2.7 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain Pkinase PF00069.20 KLO19855.1 - 5.4e-43 147.0 0.0 2.8e-42 144.6 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KLO19855.1 - 9.4e-39 133.0 0.0 4.4e-38 130.8 0.0 1.9 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 KLO19855.1 - 0.00012 21.2 0.0 0.00023 20.2 0.0 1.4 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.17 KLO19855.1 - 0.00072 18.9 0.1 0.017 14.4 0.0 2.1 2 0 0 2 2 2 1 RIO1 family APH PF01636.18 KLO19855.1 - 0.0073 16.0 0.0 0.013 15.2 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Proteasome PF00227.21 KLO19857.1 - 3.6e-47 160.1 0.2 4.2e-47 159.9 0.1 1.0 1 0 0 1 1 1 1 Proteasome subunit PCI_Csn8 PF10075.4 KLO19858.1 - 6.7e-30 103.7 0.1 9.6e-30 103.2 0.1 1.2 1 0 0 1 1 1 1 COP9 signalosome, subunit CSN8 SAC3_GANP PF03399.11 KLO19858.1 - 1.3e-29 103.2 0.0 1.9e-29 102.7 0.0 1.2 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family ECH PF00378.15 KLO19859.1 - 6.6e-66 221.9 0.0 8.1e-66 221.6 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family ECH_C PF13766.1 KLO19859.1 - 0.033 14.3 0.2 0.1 12.7 0.1 1.8 2 0 0 2 2 2 0 2-enoyl-CoA Hydratase C-terminal region Peptidase_S49 PF01343.13 KLO19859.1 - 0.085 12.6 0.2 0.24 11.1 0.1 1.8 2 0 0 2 2 2 0 Peptidase family S49 Sec10 PF07393.6 KLO19860.1 - 3.2e-224 746.2 7.7 3.9e-224 745.9 5.3 1.1 1 0 0 1 1 1 1 Exocyst complex component Sec10 Filament PF00038.16 KLO19860.1 - 0.14 11.6 6.0 0.37 10.2 1.0 2.9 2 1 1 3 3 3 0 Intermediate filament protein RIX1 PF08167.7 KLO19861.1 - 1.9e-27 95.9 2.9 1.9e-27 95.9 2.0 2.4 2 0 0 2 2 2 1 rRNA processing/ribosome biogenesis RNA_pol_I_TF PF04090.7 KLO19862.1 - 2.8e-12 46.3 0.9 1.1e-08 34.6 0.1 2.1 1 1 1 2 2 2 2 RNA polymerase I specific initiation factor Lipoprotein_20 PF13942.1 KLO19862.1 - 0.0047 16.4 0.1 0.11 11.9 0.0 2.1 1 1 1 2 2 2 1 YfhG lipoprotein TPR_16 PF13432.1 KLO19862.1 - 0.045 14.4 0.1 0.92 10.2 0.0 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_9 PF13371.1 KLO19862.1 - 0.13 12.1 0.8 13 5.6 0.0 2.6 3 0 0 3 3 3 0 Tetratricopeptide repeat RNA_pol_Rpb1_5 PF04998.12 KLO19865.1 - 3.4e-86 288.9 0.0 5.6e-86 288.2 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.15 KLO19865.1 - 2.6e-57 193.3 0.1 5.5e-57 192.3 0.1 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.13 KLO19865.1 - 2e-34 118.6 0.0 6.1e-34 117.0 0.0 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_1 PF04997.7 KLO19865.1 - 8.8e-32 110.6 0.9 1.7e-24 86.7 0.0 3.5 1 1 1 2 2 2 2 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_4 PF05000.12 KLO19865.1 - 3.2e-23 81.5 0.0 9.4e-23 80.0 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 MoeA_C PF03454.10 KLO19868.1 - 0.11 12.4 0.0 0.24 11.3 0.0 1.5 1 0 0 1 1 1 0 MoeA C-terminal region (domain IV) RRM_1 PF00076.17 KLO19869.1 - 3.3e-17 61.8 0.0 4.9e-17 61.3 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KLO19869.1 - 1.5e-13 50.5 0.0 2.6e-13 49.7 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KLO19869.1 - 1.6e-09 37.4 0.1 2.6e-09 36.7 0.1 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DEAD PF00270.24 KLO19870.1 - 2.3e-41 141.1 0.2 4.4e-41 140.1 0.2 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KLO19870.1 - 7.2e-28 96.2 0.2 1.5e-27 95.2 0.1 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 KLO19870.1 - 0.00048 19.9 0.1 0.0014 18.4 0.1 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_30 PF13604.1 KLO19870.1 - 0.0014 18.2 0.8 0.0039 16.8 0.2 2.0 2 1 0 2 2 2 1 AAA domain SecA_DEAD PF07517.9 KLO19870.1 - 0.0023 17.2 0.1 0.0065 15.7 0.0 1.7 2 0 0 2 2 2 1 SecA DEAD-like domain AAA_22 PF13401.1 KLO19870.1 - 0.004 17.3 0.1 0.011 15.8 0.1 1.7 1 1 0 1 1 1 1 AAA domain DUF1253 PF06862.7 KLO19870.1 - 0.06 11.7 0.0 2.6 6.3 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1253) tRNA-synt_1b PF00579.20 KLO19870.1 - 0.07 12.2 0.1 0.19 10.8 0.0 1.7 2 0 0 2 2 2 0 tRNA synthetases class I (W and Y) AAA_19 PF13245.1 KLO19870.1 - 0.093 12.5 0.2 0.29 10.9 0.1 1.8 1 0 0 1 1 1 0 Part of AAA domain DUF3449 PF11931.3 KLO19871.1 - 1.4e-70 236.8 0.2 1.4e-70 236.8 0.1 2.7 3 0 0 3 3 3 1 Domain of unknown function (DUF3449) SF3a60_bindingd PF12108.3 KLO19871.1 - 2.3e-10 39.8 0.4 6e-10 38.4 0.3 1.8 1 0 0 1 1 1 1 Splicing factor SF3a60 binding domain zf-met PF12874.2 KLO19871.1 - 1.8e-07 31.0 8.0 1.9e-07 31.0 1.8 2.5 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 KLO19871.1 - 1.7e-06 27.9 1.4 1.7e-06 27.9 0.9 2.6 2 1 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.2 KLO19871.1 - 0.00072 19.6 1.6 0.038 14.0 0.1 2.5 2 0 0 2 2 2 1 C2H2 type zinc-finger (2 copies) zf-DBF PF07535.7 KLO19871.1 - 0.019 14.6 3.2 0.24 11.0 0.0 2.6 2 0 0 2 2 2 0 DBF zinc finger Matrilin_ccoil PF10393.4 KLO19871.1 - 0.13 11.6 1.5 0.4 10.0 0.1 2.4 3 0 0 3 3 3 0 Trimeric coiled-coil oligomerisation domain of matrilin DUF951 PF06107.6 KLO19871.1 - 0.13 11.7 0.0 0.35 10.4 0.0 1.6 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF951) Syja_N PF02383.13 KLO19872.1 - 9.7e-77 257.8 0.0 1.3e-76 257.3 0.0 1.2 1 0 0 1 1 1 1 SacI homology domain Exo_endo_phos PF03372.18 KLO19872.1 - 1.4e-26 93.9 0.1 2.4e-26 93.2 0.0 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Abhydrolase_1 PF00561.15 KLO19874.1 - 8.5e-18 64.7 0.0 1.3e-14 54.3 0.0 2.3 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 KLO19874.1 - 5.3e-12 46.1 0.5 3.9e-11 43.2 0.3 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.15 KLO19874.1 - 0.0002 20.8 0.0 0.00031 20.2 0.0 1.3 1 0 0 1 1 1 1 Putative esterase Abhydrolase_5 PF12695.2 KLO19874.1 - 0.037 13.7 0.0 0.65 9.7 0.0 2.1 1 1 0 1 1 1 0 Alpha/beta hydrolase family Snf7 PF03357.16 KLO19876.1 - 8.2e-15 54.6 18.1 1.1e-14 54.2 12.5 1.1 1 0 0 1 1 1 1 Snf7 Ist1 PF03398.9 KLO19876.1 - 9e-06 25.1 5.4 1.4e-05 24.5 3.7 1.2 1 0 0 1 1 1 1 Regulator of Vps4 activity in the MVB pathway HAP PF03866.8 KLO19876.1 - 0.024 14.4 0.0 0.038 13.7 0.0 1.3 1 0 0 1 1 1 0 Hydrophobic abundant protein (HAP) IL28A PF15177.1 KLO19876.1 - 0.062 12.8 2.5 0.082 12.4 1.3 1.5 1 1 0 1 1 1 0 Interleukin-28A Baculo_PEP_C PF04513.7 KLO19876.1 - 0.68 9.7 5.1 0.76 9.5 1.7 2.3 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus SlyX PF04102.7 KLO19876.1 - 2.7 8.4 12.6 1.1 9.6 1.1 3.8 3 2 0 3 3 3 0 SlyX Erv26 PF04148.8 KLO19877.1 - 3e-64 216.2 7.1 4.1e-64 215.8 4.9 1.1 1 0 0 1 1 1 1 Transmembrane adaptor Erv26 DUF2909 PF11137.3 KLO19877.1 - 0.026 14.2 2.0 0.055 13.2 1.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2909) BTB PF00651.26 KLO19879.1 - 0.03 14.3 0.0 0.07 13.1 0.0 1.6 1 0 0 1 1 1 0 BTB/POZ domain UreF PF01730.11 KLO19879.1 - 0.13 12.3 0.9 12 5.9 0.1 2.4 2 0 0 2 2 2 0 UreF CorA PF01544.13 KLO19888.1 - 7e-47 159.8 0.4 9.7e-47 159.3 0.3 1.1 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein Baculo_PEP_C PF04513.7 KLO19888.1 - 0.012 15.4 0.8 0.023 14.5 0.2 1.7 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF3826 PF12875.2 KLO19888.1 - 0.041 13.5 0.4 0.79 9.3 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3826) ACT_4 PF13291.1 KLO19888.1 - 0.082 13.2 0.1 0.42 10.9 0.0 2.1 2 0 0 2 2 2 0 ACT domain PLU-1 PF08429.6 KLO19889.1 - 8e-51 172.8 8.7 8.4e-51 172.8 3.5 2.3 1 1 0 2 2 2 1 PLU-1-like protein JmjC PF02373.17 KLO19889.1 - 2.4e-40 137.3 0.5 6e-40 136.0 0.1 1.9 2 0 0 2 2 2 1 JmjC domain, hydroxylase ARID PF01388.16 KLO19889.1 - 1.5e-18 66.4 0.0 4.2e-18 64.9 0.0 1.9 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain JmjN PF02375.12 KLO19889.1 - 1.4e-15 56.5 0.2 2.8e-15 55.5 0.1 1.6 1 0 0 1 1 1 1 jmjN domain PHD PF00628.24 KLO19889.1 - 1.7e-14 53.2 40.4 1.1e-12 47.3 2.8 4.5 4 0 0 4 4 4 3 PHD-finger zf-C5HC2 PF02928.11 KLO19889.1 - 1e-12 47.8 9.9 1e-12 47.8 6.9 2.5 2 0 0 2 2 2 1 C5HC2 zinc finger Prok-RING_1 PF14446.1 KLO19889.1 - 0.0058 16.3 3.8 0.0058 16.3 2.6 4.0 4 0 0 4 4 4 2 Prokaryotic RING finger family 1 PHD_2 PF13831.1 KLO19889.1 - 0.018 14.3 25.5 0.6 9.4 0.2 4.0 4 0 0 4 4 4 0 PHD-finger Uds1 PF15456.1 KLO19890.1 - 3.9e-30 104.3 10.3 3.9e-30 104.3 7.2 5.7 3 2 2 5 5 5 1 Up-regulated During Septation V-SNARE PF05008.10 KLO19890.1 - 0.012 15.7 0.4 0.012 15.7 0.3 6.8 4 2 2 7 7 7 0 Vesicle transport v-SNARE protein N-terminus APG6 PF04111.7 KLO19890.1 - 0.041 12.9 59.8 0.045 12.8 3.6 4.7 4 1 1 5 5 5 0 Autophagy protein Apg6 HOOK PF05622.7 KLO19890.1 - 0.058 11.2 66.0 0.14 9.9 16.7 3.8 3 1 1 4 4 4 0 HOOK protein Tropomyosin_1 PF12718.2 KLO19890.1 - 5.9 6.7 72.4 2.4 7.9 4.9 5.7 4 2 1 5 5 5 0 Tropomyosin like DUF2404 PF10296.4 KLO19891.1 - 0.0001 22.3 0.1 0.00058 19.9 0.0 2.1 2 0 0 2 2 2 1 Putative integral membrane protein conserved region (DUF2404) DNA_pol3_beta_2 PF02767.11 KLO19893.1 - 0.094 12.7 0.0 0.19 11.7 0.0 1.5 1 0 0 1 1 1 0 DNA polymerase III beta subunit, central domain ORMDL PF04061.9 KLO19895.1 - 5.4e-47 158.7 1.9 7.4e-47 158.3 1.3 1.2 1 0 0 1 1 1 1 ORMDL family PIG-P PF08510.7 KLO19895.1 - 0.02 14.5 0.8 0.031 13.8 0.6 1.3 1 0 0 1 1 1 0 PIG-P THF_DHG_CYH_C PF02882.14 KLO19896.1 - 1.7e-18 66.1 0.3 1.3e-08 34.0 0.0 2.9 2 2 0 2 2 2 2 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain THF_DHG_CYH PF00763.18 KLO19896.1 - 1.2e-15 57.5 0.0 2e-15 56.8 0.0 1.4 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain Shikimate_DH PF01488.15 KLO19896.1 - 0.011 15.8 0.0 0.53 10.3 0.0 2.3 1 1 1 2 2 2 0 Shikimate / quinate 5-dehydrogenase IPP-2 PF04979.9 KLO19897.1 - 0.0013 19.0 6.6 0.3 11.3 0.0 2.4 2 1 0 2 2 2 2 Protein phosphatase inhibitor 2 (IPP-2) RGM_C PF06534.8 KLO19897.1 - 0.069 12.3 0.0 0.11 11.7 0.0 1.3 1 0 0 1 1 1 0 Repulsive guidance molecule (RGM) C-terminus AAA PF00004.24 KLO19898.1 - 4e-58 195.3 0.0 2.3e-40 137.8 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 KLO19898.1 - 9.1e-11 42.0 0.8 0.00049 20.2 0.1 4.2 2 2 1 3 3 3 2 AAA domain AAA_2 PF07724.9 KLO19898.1 - 3.7e-10 39.9 0.0 3.2e-06 27.1 0.0 3.0 3 0 0 3 3 2 2 AAA domain (Cdc48 subfamily) AAA_16 PF13191.1 KLO19898.1 - 1.4e-09 38.2 0.3 0.0048 16.8 0.1 3.4 2 1 0 3 3 3 2 AAA ATPase domain AAA_5 PF07728.9 KLO19898.1 - 5e-09 36.0 0.1 0.00083 19.0 0.0 3.5 4 0 0 4 4 3 2 AAA domain (dynein-related subfamily) AAA_17 PF13207.1 KLO19898.1 - 4.2e-08 34.0 0.0 0.0087 16.8 0.0 2.8 2 0 0 2 2 2 2 AAA domain RuvB_N PF05496.7 KLO19898.1 - 1.2e-07 31.0 0.1 0.013 14.5 0.0 2.5 2 0 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus AAA_33 PF13671.1 KLO19898.1 - 1.8e-07 31.1 0.0 0.0084 15.9 0.0 2.5 2 0 0 2 2 2 2 AAA domain CDC48_2 PF02933.12 KLO19898.1 - 1.9e-07 30.6 0.6 5.9e-06 25.8 0.1 2.5 2 0 0 2 2 2 1 Cell division protein 48 (CDC48), domain 2 TIP49 PF06068.8 KLO19898.1 - 1.9e-07 30.1 0.1 0.005 15.5 0.0 2.5 3 0 0 3 3 2 2 TIP49 C-terminus Sigma54_activat PF00158.21 KLO19898.1 - 2.1e-07 30.6 0.1 0.02 14.3 0.0 3.6 3 0 0 3 3 3 2 Sigma-54 interaction domain AAA_14 PF13173.1 KLO19898.1 - 2.1e-07 30.9 0.0 0.006 16.4 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.1 KLO19898.1 - 6.1e-07 29.0 0.2 0.068 12.9 0.0 2.9 3 0 0 3 3 3 2 Part of AAA domain RNA_helicase PF00910.17 KLO19898.1 - 1.8e-06 28.0 0.0 0.053 13.7 0.0 2.8 2 0 0 2 2 2 2 RNA helicase ABC_tran PF00005.22 KLO19898.1 - 3.1e-06 27.5 0.1 0.059 13.6 0.0 3.0 3 0 0 3 3 3 2 ABC transporter IstB_IS21 PF01695.12 KLO19898.1 - 3.3e-06 26.6 0.8 0.051 12.9 0.0 2.7 3 0 0 3 3 2 2 IstB-like ATP binding protein Mg_chelatase PF01078.16 KLO19898.1 - 4.5e-06 25.9 0.3 0.0054 15.9 0.1 2.4 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_24 PF13479.1 KLO19898.1 - 5.9e-06 26.0 0.9 0.047 13.2 0.1 2.8 2 1 0 2 2 2 2 AAA domain AAA_18 PF13238.1 KLO19898.1 - 6.5e-06 26.4 0.2 0.019 15.2 0.0 3.1 4 0 0 4 4 2 1 AAA domain AAA_25 PF13481.1 KLO19898.1 - 1.4e-05 24.6 5.8 0.83 9.0 0.0 4.5 2 2 1 5 5 4 2 AAA domain NACHT PF05729.7 KLO19898.1 - 2.2e-05 24.2 1.6 0.026 14.1 0.0 3.3 4 0 0 4 4 4 1 NACHT domain Arch_ATPase PF01637.13 KLO19898.1 - 4.3e-05 23.3 0.1 1.7 8.2 0.0 4.0 2 2 1 3 3 3 1 Archaeal ATPase Zeta_toxin PF06414.7 KLO19898.1 - 4.3e-05 22.6 0.1 0.12 11.4 0.0 2.3 2 0 0 2 2 2 2 Zeta toxin KaiC PF06745.8 KLO19898.1 - 6.2e-05 22.2 0.4 0.0026 16.8 0.1 2.4 2 0 0 2 2 2 1 KaiC AAA_30 PF13604.1 KLO19898.1 - 6.9e-05 22.5 0.0 0.25 10.9 0.0 2.3 2 0 0 2 2 2 2 AAA domain UPF0079 PF02367.12 KLO19898.1 - 0.00022 20.8 0.1 0.5 10.0 0.0 2.4 2 0 0 2 2 2 2 Uncharacterised P-loop hydrolase UPF0079 AAA_28 PF13521.1 KLO19898.1 - 0.00041 20.3 0.0 1.1 9.1 0.0 2.6 3 0 0 3 3 2 2 AAA domain PhoH PF02562.11 KLO19898.1 - 0.0006 19.1 0.0 1.1 8.4 0.0 2.4 2 0 0 2 2 2 2 PhoH-like protein Parvo_NS1 PF01057.12 KLO19898.1 - 0.00078 18.3 0.0 0.71 8.6 0.0 2.2 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 AAA_3 PF07726.6 KLO19898.1 - 0.00094 18.7 0.0 0.14 11.7 0.0 2.5 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) NB-ARC PF00931.17 KLO19898.1 - 0.001 17.9 0.1 0.72 8.6 0.0 2.4 2 0 0 2 2 2 2 NB-ARC domain KAP_NTPase PF07693.9 KLO19898.1 - 0.0032 16.4 0.1 8.7 5.2 0.0 3.1 2 1 0 3 3 3 0 KAP family P-loop domain T2SE PF00437.15 KLO19898.1 - 0.004 16.0 0.0 2.3 7.0 0.0 2.5 2 0 0 2 2 2 1 Type II/IV secretion system protein CPT PF07931.7 KLO19898.1 - 0.0077 15.8 0.0 0.12 11.9 0.0 2.3 2 0 0 2 2 2 1 Chloramphenicol phosphotransferase-like protein Sigma54_activ_2 PF14532.1 KLO19898.1 - 0.01 15.8 0.1 7.6 6.5 0.0 3.0 2 1 0 2 2 2 0 Sigma-54 interaction domain AAA_29 PF13555.1 KLO19898.1 - 0.012 15.1 0.2 0.49 9.9 0.0 2.5 2 0 0 2 2 2 0 P-loop containing region of AAA domain DEAD PF00270.24 KLO19898.1 - 0.013 14.9 0.4 15 5.0 0.1 3.9 2 2 2 4 4 4 0 DEAD/DEAH box helicase ResIII PF04851.10 KLO19898.1 - 0.016 15.0 0.0 4.9 6.9 0.0 2.5 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit AAA_11 PF13086.1 KLO19898.1 - 0.016 14.7 0.0 0.85 9.1 0.0 2.3 2 0 0 2 2 2 0 AAA domain DUF2075 PF09848.4 KLO19898.1 - 0.017 14.1 0.0 0.74 8.7 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) DUF815 PF05673.8 KLO19898.1 - 0.023 13.6 0.0 2.6 6.9 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF815) AAA_10 PF12846.2 KLO19898.1 - 0.038 13.4 0.1 2.7 7.3 0.0 2.4 2 1 0 2 2 2 0 AAA-like domain IPT PF01745.11 KLO19898.1 - 0.065 12.3 0.1 1.5 7.8 0.0 2.3 2 0 0 2 2 2 0 Isopentenyl transferase DAP3 PF10236.4 KLO19898.1 - 0.079 11.8 0.0 7.1 5.4 0.0 2.6 2 0 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 KTI12 PF08433.5 KLO19898.1 - 0.096 11.8 0.1 0.94 8.6 0.0 2.2 2 0 0 2 2 2 0 Chromatin associated protein KTI12 TrwB_AAD_bind PF10412.4 KLO19898.1 - 0.13 10.8 0.2 5 5.6 0.0 2.2 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain AAA_23 PF13476.1 KLO19898.1 - 0.13 12.5 0.0 4.8 7.4 0.0 2.4 2 0 0 2 2 2 0 AAA domain DUF2009 PF09418.5 KLO19899.1 - 2.1e-203 676.2 0.0 2.4e-203 676.0 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2009) zf-B_box PF00643.19 KLO19899.1 - 2.8e-07 30.3 6.7 5e-07 29.4 4.6 1.5 1 0 0 1 1 1 1 B-box zinc finger IBR PF01485.16 KLO19899.1 - 0.086 12.7 6.5 0.21 11.4 4.5 1.6 1 0 0 1 1 1 0 IBR domain DUF3661 PF12400.3 KLO19900.1 - 1.4e-36 125.4 3.6 2e-36 124.9 2.5 1.2 1 0 0 1 1 1 1 Vaculolar membrane protein Sec62 PF03839.11 KLO19900.1 - 0.0004 19.8 0.2 0.00074 18.9 0.1 1.4 1 0 0 1 1 1 1 Translocation protein Sec62 dsrm PF00035.20 KLO19903.1 - 4.2e-10 40.0 0.0 7.3e-10 39.2 0.0 1.4 1 0 0 1 1 1 1 Double-stranded RNA binding motif DUF3933 PF13069.1 KLO19903.1 - 0.18 11.5 1.3 0.3 10.8 0.9 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3933) PCI PF01399.22 KLO19907.1 - 6.6e-15 55.3 0.2 1.6e-14 54.0 0.1 1.8 2 0 0 2 2 2 1 PCI domain Pro-kuma_activ PF09286.6 KLO19908.1 - 3.1e-38 131.0 0.1 5.3e-38 130.2 0.0 1.4 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.17 KLO19908.1 - 2e-07 30.4 1.1 2.5e-07 30.1 0.1 1.5 2 0 0 2 2 2 1 Subtilase family Pro-kuma_activ PF09286.6 KLO19909.1 - 2.3e-38 131.4 0.0 6.2e-38 130.0 0.0 1.7 2 0 0 2 2 2 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.17 KLO19909.1 - 6.9e-05 22.1 0.0 0.00021 20.5 0.0 1.4 1 1 0 1 1 1 1 Subtilase family Hep_59 PF07052.6 KLO19910.1 - 3.5e-27 94.8 1.5 3.5e-27 94.8 1.0 2.3 2 1 0 2 2 2 1 Hepatocellular carcinoma-associated antigen 59 DUF3353 PF11833.3 KLO19910.1 - 0.37 10.2 1.4 0.74 9.2 0.6 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF3353) RNA_pol_Rpb2_4 PF04566.8 KLO19911.1 - 0.1 12.4 0.3 0.78 9.5 0.0 2.3 3 0 0 3 3 3 0 RNA polymerase Rpb2, domain 4 UPF0075 PF03702.9 KLO19913.1 - 0.07 12.0 0.0 0.12 11.2 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0075) DLIC PF05783.6 KLO19915.1 - 6.3e-42 143.8 9.3 1.1e-35 123.2 0.0 4.0 2 2 1 3 3 3 2 Dynein light intermediate chain (DLIC) AAA_16 PF13191.1 KLO19915.1 - 0.0029 17.6 0.1 0.0094 15.9 0.0 1.9 3 0 0 3 3 3 1 AAA ATPase domain GTP_EFTU PF00009.22 KLO19915.1 - 0.0071 15.7 0.0 0.26 10.6 0.0 2.2 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain AAA_18 PF13238.1 KLO19915.1 - 0.018 15.3 0.0 0.043 14.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.18 KLO19915.1 - 0.026 14.5 0.0 0.051 13.5 0.0 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase PduV-EutP PF10662.4 KLO19915.1 - 0.053 13.0 0.0 0.13 11.7 0.0 1.6 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_28 PF13521.1 KLO19915.1 - 0.057 13.3 0.0 0.17 11.8 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.1 KLO19915.1 - 0.06 12.7 0.0 0.34 10.2 0.0 2.1 2 0 0 2 2 2 0 AAA domain DUF4508 PF14969.1 KLO19915.1 - 0.076 13.0 0.1 0.15 12.0 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4508) AAA_22 PF13401.1 KLO19915.1 - 0.083 13.0 0.0 0.52 10.4 0.0 2.3 2 0 0 2 2 2 0 AAA domain T2SE PF00437.15 KLO19915.1 - 0.1 11.4 0.0 0.16 10.8 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_29 PF13555.1 KLO19915.1 - 0.12 11.9 0.1 0.28 10.7 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain TIP41 PF04176.8 KLO19916.1 - 4.5e-55 185.7 0.0 5.5e-55 185.4 0.0 1.1 1 0 0 1 1 1 1 TIP41-like family RRM_1 PF00076.17 KLO19917.1 - 0.00025 20.6 0.0 0.00052 19.5 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KLO19917.1 - 0.0075 16.0 0.0 0.013 15.2 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KLO19917.1 - 0.071 13.0 0.0 0.22 11.5 0.0 1.8 2 0 0 2 2 2 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 KLO19918.1 - 0.08 12.5 0.1 11 5.6 0.0 2.6 2 1 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) F-box-like PF12937.2 KLO19922.1 - 0.0003 20.4 8.3 0.00075 19.1 3.0 3.0 2 1 0 2 2 2 1 F-box-like F-box-like PF12937.2 KLO19923.1 - 1.9e-05 24.2 0.7 0.00036 20.2 0.1 2.6 2 0 0 2 2 2 1 F-box-like Tetraspannin PF00335.15 KLO19924.1 - 5.2 6.2 8.3 19 4.4 5.8 1.9 1 1 0 1 1 1 0 Tetraspanin family Abhydrolase_6 PF12697.2 KLO19926.1 - 5.8e-35 121.2 0.0 9.2e-35 120.5 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KLO19926.1 - 2.5e-22 79.5 0.0 4.4e-22 78.7 0.0 1.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 KLO19926.1 - 6.2e-14 51.9 0.0 1.2e-13 51.0 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Ndr PF03096.9 KLO19926.1 - 1.3e-07 30.3 0.0 2.6e-07 29.4 0.0 1.4 1 0 0 1 1 1 1 Ndr family DLH PF01738.13 KLO19926.1 - 0.0004 19.7 0.0 0.92 8.7 0.0 3.0 2 1 1 3 3 3 2 Dienelactone hydrolase family Hydrolase_4 PF12146.3 KLO19926.1 - 0.00056 19.7 0.2 0.0013 18.5 0.0 1.8 2 0 0 2 2 2 1 Putative lysophospholipase Abhydrolase_4 PF08386.5 KLO19926.1 - 0.0028 17.5 0.0 0.0048 16.7 0.0 1.3 1 0 0 1 1 1 1 TAP-like protein PAF-AH_p_II PF03403.8 KLO19926.1 - 0.098 10.9 0.0 0.31 9.2 0.0 1.7 2 0 0 2 2 2 0 Platelet-activating factor acetylhydrolase, isoform II Btz PF09405.5 KLO19927.1 - 4.7e-08 33.1 7.7 4.7e-08 33.1 5.3 2.4 2 1 1 3 3 3 1 CASC3/Barentsz eIF4AIII binding TFIIB PF00382.14 KLO19928.1 - 3e-35 119.8 0.1 4.4e-22 77.6 0.1 2.8 3 0 0 3 3 3 2 Transcription factor TFIIB repeat TF_Zn_Ribbon PF08271.7 KLO19928.1 - 1.2e-12 46.9 1.2 1.9e-12 46.2 0.8 1.4 1 0 0 1 1 1 1 TFIIB zinc-binding Guanylin PF02058.10 KLO19928.1 - 0.002 18.1 0.6 0.46 10.5 0.0 2.7 2 1 1 3 3 3 1 Guanylin precursor Cyclin_C PF02984.14 KLO19928.1 - 0.017 15.0 0.0 0.28 11.1 0.0 2.2 2 0 0 2 2 2 0 Cyclin, C-terminal domain Sigma70_r4 PF04545.11 KLO19928.1 - 0.024 13.9 0.0 0.14 11.4 0.0 2.3 3 0 0 3 3 3 0 Sigma-70, region 4 Cyclin_N PF00134.18 KLO19928.1 - 0.029 13.9 0.1 0.049 13.2 0.1 1.3 1 0 0 1 1 1 0 Cyclin, N-terminal domain RRS1 PF04939.7 KLO19929.1 - 1.8e-57 193.4 8.2 3.1e-57 192.6 5.7 1.4 1 0 0 1 1 1 1 Ribosome biogenesis regulatory protein (RRS1) SMK-1 PF04802.10 KLO19930.1 - 7.4e-65 218.1 2.9 3.4e-64 215.9 2.0 2.0 1 1 0 1 1 1 1 Component of IIS longevity pathway SMK-1 Abhydrolase_2 PF02230.11 KLO19931.1 - 1.3e-55 188.1 0.0 1e-54 185.2 0.0 1.9 1 1 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_5 PF12695.2 KLO19931.1 - 1.7e-11 44.0 0.0 2.5e-11 43.5 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KLO19931.1 - 4.4e-08 33.2 0.0 2e-07 31.1 0.0 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family FSH1 PF03959.8 KLO19931.1 - 0.0044 16.4 0.0 0.011 15.1 0.0 1.7 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Esterase PF00756.15 KLO19931.1 - 0.019 14.4 0.0 0.023 14.1 0.0 1.3 1 1 0 1 1 1 0 Putative esterase Lipase_3 PF01764.20 KLO19931.1 - 0.023 14.3 0.0 0.037 13.6 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) Abhydrolase_3 PF07859.8 KLO19931.1 - 0.033 13.7 0.0 0.042 13.4 0.0 1.4 1 1 0 1 1 1 0 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 KLO19931.1 - 0.14 11.3 0.5 1.2 8.2 0.1 2.5 2 1 1 3 3 3 0 Prolyl oligopeptidase family tRNA_m1G_MT PF01746.16 KLO19932.1 - 3.9e-34 117.8 0.3 3.9e-34 117.8 0.2 1.7 2 1 0 2 2 2 1 tRNA (Guanine-1)-methyltransferase BLVR PF06375.6 KLO19932.1 - 0.022 14.5 6.3 0.058 13.2 4.4 1.7 1 0 0 1 1 1 0 Bovine leukaemia virus receptor (BLVR) NARP1 PF12569.3 KLO19932.1 - 0.096 11.4 12.2 0.19 10.4 8.4 1.4 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 DUF1906 PF08924.6 KLO19932.1 - 3.8 7.3 6.1 1.1 9.0 0.0 2.9 3 1 0 3 3 3 0 Domain of unknown function (DUF1906) Methyltransf_23 PF13489.1 KLO19933.1 - 7.2e-12 45.3 0.0 1.1e-11 44.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KLO19933.1 - 1.7e-10 41.2 0.0 3.3e-10 40.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KLO19933.1 - 1.8e-09 37.9 0.0 3.2e-09 37.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KLO19933.1 - 6.8e-08 32.2 0.0 1e-07 31.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KLO19933.1 - 0.00021 20.7 0.0 0.00032 20.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_18 PF12847.2 KLO19933.1 - 0.0023 18.5 0.0 0.0049 17.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain DREV PF05219.7 KLO19933.1 - 0.0045 15.9 0.0 0.0073 15.2 0.0 1.3 1 0 0 1 1 1 1 DREV methyltransferase RrnaAD PF00398.15 KLO19933.1 - 0.0067 15.4 0.0 0.0089 15.0 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_32 PF13679.1 KLO19933.1 - 0.018 14.7 0.0 0.029 14.0 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_25 PF13649.1 KLO19933.1 - 0.075 13.4 0.0 0.15 12.3 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain zf-C2H2 PF00096.21 KLO19934.1 - 6 7.4 12.7 2.1 8.8 0.7 3.4 3 0 0 3 3 3 0 Zinc finger, C2H2 type RNA_pol_Rpb2_6 PF00562.23 KLO19936.1 - 3e-111 371.8 0.0 4e-111 371.4 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.10 KLO19936.1 - 3e-29 101.4 0.0 4.8e-29 100.7 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_3 PF04565.11 KLO19936.1 - 1.1e-25 89.1 0.0 2.4e-25 88.0 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpa2_4 PF06883.7 KLO19936.1 - 9.6e-23 79.9 0.0 2.3e-22 78.7 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase I, Rpa2 specific domain RNA_pol_Rpb2_2 PF04561.9 KLO19936.1 - 4.6e-20 71.8 0.0 8.5e-20 70.9 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_7 PF04560.15 KLO19936.1 - 5.8e-18 64.9 0.0 9.9e-17 60.9 0.0 2.4 1 1 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_5 PF04567.12 KLO19936.1 - 0.047 13.6 0.0 0.1 12.6 0.0 1.5 1 0 0 1 1 1 0 RNA polymerase Rpb2, domain 5 UCH PF00443.24 KLO19937.1 - 2.7e-52 177.5 0.1 4e-52 176.9 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 KLO19937.1 - 7.1e-22 78.2 0.0 1.6e-21 77.0 0.0 1.6 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Peptidase_C98 PF15499.1 KLO19937.1 - 0.05 12.8 0.3 0.96 8.6 0.1 2.8 2 1 0 2 2 2 0 Ubiquitin-specific peptidase-like, SUMO isopeptidase zf-H2C2_2 PF13465.1 KLO19938.1 - 1e-14 53.9 25.0 4.6e-09 36.1 0.5 5.1 5 0 0 5 5 5 3 Zinc-finger double domain zf-C2H2 PF00096.21 KLO19938.1 - 1.3e-06 28.4 28.9 0.0006 19.9 0.2 4.9 4 1 0 4 4 4 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KLO19938.1 - 1.4e-05 25.0 22.3 0.047 14.0 0.1 4.5 4 0 0 4 4 4 3 C2H2-type zinc finger zf-B_box PF00643.19 KLO19938.1 - 0.3 11.0 6.4 0.12 12.3 1.8 2.3 2 0 0 2 2 2 0 B-box zinc finger C1_2 PF03107.11 KLO19938.1 - 0.3 11.2 5.5 9.5 6.4 1.3 2.5 2 0 0 2 2 2 0 C1 domain Rad50_zn_hook PF04423.9 KLO19938.1 - 0.38 10.2 3.6 1.1 8.7 0.1 2.3 2 0 0 2 2 2 0 Rad50 zinc hook motif IBR PF01485.16 KLO19938.1 - 2.6 7.9 14.2 3.4 7.6 4.1 3.3 2 1 1 3 3 3 0 IBR domain zf-met PF12874.2 KLO19938.1 - 3 8.1 20.6 0.57 10.4 0.6 4.8 4 1 0 4 4 4 0 Zinc-finger of C2H2 type zf-C2HC_2 PF13913.1 KLO19938.1 - 8 6.2 7.9 6.1 6.6 0.1 3.2 3 0 0 3 3 3 0 zinc-finger of a C2HC-type F-box PF00646.28 KLO19939.1 - 1.6e-05 24.4 2.0 1.6e-05 24.4 1.4 2.0 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.2 KLO19939.1 - 0.0025 17.5 2.0 0.0032 17.1 0.4 2.0 2 0 0 2 2 2 1 F-box-like LNS2 PF08235.8 KLO19940.1 - 9.7e-72 239.6 0.0 1.4e-71 239.1 0.0 1.3 1 0 0 1 1 1 1 LNS2 (Lipin/Ned1/Smp2) Lipin_N PF04571.9 KLO19940.1 - 8.9e-32 109.0 0.0 2.3e-31 107.7 0.0 1.7 2 0 0 2 2 2 1 lipin, N-terminal conserved region Acid_phosphat_B PF03767.9 KLO19940.1 - 0.065 12.5 0.1 0.3 10.4 0.0 1.9 2 0 0 2 2 2 0 HAD superfamily, subfamily IIIB (Acid phosphatase) PP2C PF00481.16 KLO19941.1 - 4.9e-24 85.0 0.0 2.3e-22 79.6 0.0 2.7 2 1 0 2 2 2 1 Protein phosphatase 2C PP2C_2 PF13672.1 KLO19941.1 - 6.1e-05 22.5 0.0 0.00033 20.1 0.0 2.1 1 1 0 1 1 1 1 Protein phosphatase 2C DUF2914 PF11141.3 KLO19941.1 - 2.3 7.8 6.0 0.42 10.1 0.1 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF2914) Na_H_Exchanger PF00999.16 KLO19943.1 - 2.4e-62 210.6 51.9 3.4e-62 210.1 36.0 1.2 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family His_biosynth PF00977.16 KLO19944.1 - 3.5e-34 118.0 0.0 4.7e-34 117.6 0.0 1.1 1 0 0 1 1 1 1 Histidine biosynthesis protein TB2_DP1_HVA22 PF03134.14 KLO19945.1 - 2.7e-07 30.2 0.2 5.3e-07 29.2 0.2 1.5 1 1 0 1 1 1 1 TB2/DP1, HVA22 family Fe-ADH PF00465.14 KLO19947.1 - 6.5e-88 294.8 0.0 8.7e-88 294.4 0.0 1.1 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.1 KLO19947.1 - 4.2e-12 45.8 0.0 3.2e-08 33.1 0.0 2.2 2 0 0 2 2 2 2 Iron-containing alcohol dehydrogenase zf-Nse PF11789.3 KLO19947.1 - 0.12 11.9 0.3 0.32 10.5 0.2 1.8 2 0 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit ATP-synt_C PF00137.16 KLO19947.1 - 0.18 11.7 1.2 0.41 10.5 0.8 1.6 1 0 0 1 1 1 0 ATP synthase subunit C Acetyltransf_8 PF13523.1 KLO19948.1 - 2.7e-30 105.2 0.5 3.9e-30 104.7 0.4 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain F-box-like PF12937.2 KLO19949.1 - 0.0017 18.0 0.1 0.004 16.8 0.0 1.7 1 0 0 1 1 1 1 F-box-like LRR_6 PF13516.1 KLO19949.1 - 0.43 10.8 2.7 5.8 7.3 0.0 4.0 4 0 0 4 4 4 0 Leucine Rich repeat F-box-like PF12937.2 KLO19950.1 - 7.6e-05 22.3 0.9 0.0004 20.0 0.2 2.7 2 0 0 2 2 2 1 F-box-like LRR_1 PF00560.28 KLO19950.1 - 0.015 15.2 2.1 35 4.9 0.4 4.7 4 0 0 4 4 4 0 Leucine Rich Repeat LRR_7 PF13504.1 KLO19950.1 - 1.4 9.4 11.5 46 4.8 0.1 6.2 7 0 0 7 7 7 0 Leucine rich repeat Polysacc_deac_1 PF01522.16 KLO19951.1 - 1.7e-25 89.0 0.1 2.5e-24 85.2 0.0 2.3 2 0 0 2 2 2 1 Polysaccharide deacetylase F-box-like PF12937.2 KLO19953.1 - 0.0011 18.6 0.3 0.0011 18.6 0.2 2.0 2 0 0 2 2 2 1 F-box-like LSM PF01423.17 KLO19954.1 - 4.3e-13 48.6 0.1 5.3e-13 48.3 0.1 1.2 1 0 0 1 1 1 1 LSM domain PhnA PF03831.9 KLO19954.1 - 0.12 11.7 0.0 0.85 9.0 0.0 2.1 2 0 0 2 2 2 0 PhnA protein Ribophorin_I PF04597.9 KLO19956.1 - 2.5e-119 398.6 0.1 2.8e-119 398.4 0.1 1.0 1 0 0 1 1 1 1 Ribophorin I DUF378 PF04070.7 KLO19957.1 - 0.036 13.6 0.4 0.06 12.9 0.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF378) PPR_2 PF13041.1 KLO19958.1 - 1.6e-15 56.7 8.2 2.8e-10 40.0 0.2 5.3 5 1 1 6 6 6 2 PPR repeat family PPR PF01535.15 KLO19958.1 - 1.8e-09 36.9 10.0 0.55 10.3 0.0 7.5 7 0 0 7 7 7 3 PPR repeat PPR_3 PF13812.1 KLO19958.1 - 0.00033 20.7 5.2 33 5.1 0.0 6.5 7 0 0 7 7 7 1 Pentatricopeptide repeat domain PPR_1 PF12854.2 KLO19958.1 - 0.00042 19.7 6.9 0.32 10.5 0.0 5.2 6 0 0 6 6 6 2 PPR repeat Asp PF00026.18 KLO19959.1 - 2.1e-30 106.0 0.1 7.3e-29 101.0 0.0 2.2 1 1 0 1 1 1 1 Eukaryotic aspartyl protease Asp_protease_2 PF13650.1 KLO19959.1 - 0.0014 19.0 0.3 0.15 12.5 0.0 3.0 3 0 0 3 3 3 1 Aspartyl protease Protocadherin PF08374.6 KLO19959.1 - 0.0057 16.3 0.1 0.012 15.2 0.1 1.4 1 0 0 1 1 1 1 Protocadherin gag-asp_proteas PF13975.1 KLO19959.1 - 0.14 11.9 1.2 15 5.4 0.0 3.2 3 0 0 3 3 3 0 gag-polyprotein putative aspartyl protease F-box-like PF12937.2 KLO19960.1 - 0.00026 20.6 0.6 0.0021 17.7 0.4 2.4 1 1 0 1 1 1 1 F-box-like LRR_4 PF12799.2 KLO19960.1 - 1.9 8.2 6.6 3.7 7.2 0.0 4.0 1 1 2 3 3 3 0 Leucine Rich repeats (2 copies) F-box-like PF12937.2 KLO19961.1 - 0.0034 17.0 0.3 0.01 15.5 0.2 1.8 1 0 0 1 1 1 1 F-box-like F-box-like PF12937.2 KLO19962.1 - 0.00028 20.5 0.1 0.001 18.7 0.0 2.2 2 0 0 2 2 2 1 F-box-like DNA_pol_B_3 PF08408.5 KLO19962.1 - 0.06 13.2 0.0 0.11 12.3 0.0 1.3 1 0 0 1 1 1 0 DNA polymerase family B viral insert LRR_4 PF12799.2 KLO19962.1 - 8.5 6.1 11.2 6 6.6 0.5 4.6 3 1 1 4 4 4 0 Leucine Rich repeats (2 copies) F-box-like PF12937.2 KLO19963.1 - 0.0071 16.0 0.0 0.022 14.4 0.0 1.8 1 0 0 1 1 1 1 F-box-like Erf4 PF10256.4 KLO19963.1 - 0.091 12.6 0.0 0.2 11.4 0.0 1.6 1 0 0 1 1 1 0 Golgin subfamily A member 7/ERF4 family LRR_7 PF13504.1 KLO19963.1 - 2.3 8.8 4.4 94 3.9 0.0 4.7 5 1 0 5 5 5 0 Leucine rich repeat peroxidase PF00141.18 KLO19965.1 - 6.3e-28 97.8 0.0 1.2e-27 96.9 0.0 1.5 1 0 0 1 1 1 1 Peroxidase DUF3415 PF11895.3 KLO19965.1 - 1.6e-24 85.5 2.6 3.4e-24 84.4 1.8 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3415) Pkinase PF00069.20 KLO19966.1 - 2.5e-67 226.7 0.0 3.4e-67 226.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KLO19966.1 - 9.6e-44 149.3 0.0 1.4e-43 148.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KLO19966.1 - 0.00044 19.3 0.0 0.00093 18.2 0.0 1.5 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 KLO19966.1 - 0.0057 16.4 0.0 0.45 10.2 0.0 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family zf-C2H2 PF00096.21 KLO19967.1 - 1.8e-08 34.2 9.4 0.00084 19.5 1.1 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 KLO19967.1 - 4.5e-05 23.5 7.6 7e-05 22.9 0.6 3.1 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.1 KLO19967.1 - 0.00047 20.3 8.2 0.23 11.8 0.9 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 KLO19967.1 - 0.19 11.9 1.2 9.5 6.5 0.1 2.4 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-BED PF02892.10 KLO19967.1 - 1.5 8.6 5.8 7.8 6.3 0.5 2.4 1 1 1 2 2 2 0 BED zinc finger RFX5_DNA_bdg PF14621.1 KLO19968.1 - 0.097 12.2 0.1 0.14 11.7 0.1 1.2 1 0 0 1 1 1 0 RFX5 DNA-binding domain TFIIF_alpha PF05793.7 KLO19969.1 - 7.5e-13 47.6 71.2 1.3e-08 33.7 35.1 5.2 2 2 2 4 4 4 3 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) DUF3415 PF11895.3 KLO19970.1 - 2.5e-25 88.1 2.3 5.4e-25 87.0 1.6 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3415) peroxidase PF00141.18 KLO19970.1 - 4e-17 62.4 0.1 8.6e-17 61.3 0.0 1.5 2 0 0 2 2 2 1 Peroxidase DUF500 PF04366.7 KLO19971.1 - 6.7e-38 128.9 0.1 1e-37 128.4 0.1 1.2 1 0 0 1 1 1 1 Family of unknown function (DUF500) SH3_1 PF00018.23 KLO19971.1 - 8.5e-16 57.0 0.1 2e-15 55.8 0.1 1.7 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 KLO19971.1 - 1.2e-13 50.4 0.0 2.4e-13 49.4 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 KLO19971.1 - 5.4e-11 41.8 0.1 2.1e-10 39.9 0.0 2.0 2 0 0 2 2 2 1 Variant SH3 domain PIF1 PF05970.9 KLO19972.1 - 1.5e-57 195.2 0.3 5.5e-55 186.7 0.2 2.2 1 1 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.1 KLO19972.1 - 3.9e-12 46.1 0.0 2.4e-11 43.6 0.0 2.1 1 1 0 1 1 1 1 AAA domain Herpes_Helicase PF02689.9 KLO19972.1 - 5.2e-08 31.1 0.3 0.00016 19.5 0.0 2.3 2 0 0 2 2 2 2 Helicase UvrD_C_2 PF13538.1 KLO19972.1 - 6.8e-06 26.1 0.2 6.3e-05 23.0 0.1 2.3 1 1 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA_22 PF13401.1 KLO19972.1 - 0.00065 19.8 0.0 0.002 18.2 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 KLO19972.1 - 0.0013 18.7 0.4 0.0032 17.4 0.3 1.6 1 0 0 1 1 1 1 AAA ATPase domain AAA_19 PF13245.1 KLO19972.1 - 0.0025 17.5 0.7 0.0055 16.4 0.5 1.6 1 0 0 1 1 1 1 Part of AAA domain Viral_helicase1 PF01443.13 KLO19972.1 - 0.0036 16.8 0.6 0.36 10.3 0.0 2.6 2 1 0 2 2 2 1 Viral (Superfamily 1) RNA helicase PhoH PF02562.11 KLO19972.1 - 0.012 14.8 0.0 0.044 13.0 0.0 1.9 1 0 0 1 1 1 0 PhoH-like protein MMR_HSR1 PF01926.18 KLO19972.1 - 0.012 15.5 0.1 2 8.4 0.1 2.4 2 0 0 2 2 2 0 50S ribosome-binding GTPase Mg_chelatase PF01078.16 KLO19972.1 - 0.017 14.3 0.1 0.031 13.4 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI MobB PF03205.9 KLO19972.1 - 0.02 14.6 0.4 0.073 12.7 0.2 2.1 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_29 PF13555.1 KLO19972.1 - 0.025 14.0 0.1 0.052 13.0 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_11 PF13086.1 KLO19972.1 - 0.038 13.5 0.1 7.7 6.0 0.0 2.7 1 1 1 2 2 2 0 AAA domain TrwB_AAD_bind PF10412.4 KLO19972.1 - 0.042 12.4 0.1 0.076 11.6 0.1 1.3 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain NACHT PF05729.7 KLO19972.1 - 0.047 13.3 0.0 0.089 12.4 0.0 1.4 1 0 0 1 1 1 0 NACHT domain NTPase_1 PF03266.10 KLO19972.1 - 0.054 13.2 0.5 0.26 10.9 0.1 2.2 2 0 0 2 2 2 0 NTPase ABC_tran PF00005.22 KLO19972.1 - 0.06 13.6 0.2 0.14 12.4 0.1 1.7 1 0 0 1 1 1 0 ABC transporter AAA_5 PF07728.9 KLO19972.1 - 0.068 12.8 0.2 0.45 10.2 0.2 2.4 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) DUF2075 PF09848.4 KLO19972.1 - 0.07 12.0 1.0 0.16 10.9 0.1 1.9 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) UPF0079 PF02367.12 KLO19972.1 - 0.11 12.1 0.9 1.1 8.8 0.0 2.2 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 DUF258 PF03193.11 KLO19972.1 - 0.14 11.3 0.1 0.39 9.9 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function, DUF258 RhoGAP PF00620.22 KLO19973.1 - 2.1e-37 128.0 0.0 4.8e-37 126.9 0.0 1.6 1 0 0 1 1 1 1 RhoGAP domain FCH PF00611.18 KLO19973.1 - 5.4e-11 42.5 0.3 4e-10 39.7 0.1 2.5 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain TEX12 PF15219.1 KLO19973.1 - 0.0074 16.2 0.0 0.024 14.5 0.0 1.9 1 0 0 1 1 1 1 Testis-expressed 12 DUF3287 PF11690.3 KLO19973.1 - 0.17 11.9 1.7 0.85 9.7 0.2 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF3287) ABC_membrane PF00664.18 KLO19974.1 - 1.6e-45 155.7 21.8 5.9e-28 98.0 1.4 4.3 3 1 1 4 4 4 4 ABC transporter transmembrane region ABC_tran PF00005.22 KLO19974.1 - 1.9e-44 151.2 0.0 8.5e-26 90.8 0.0 3.4 3 0 0 3 3 3 2 ABC transporter SMC_N PF02463.14 KLO19974.1 - 9.7e-12 44.5 0.0 0.0004 19.6 0.0 4.1 2 1 1 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 KLO19974.1 - 9e-11 42.2 1.2 0.017 15.0 0.2 4.2 2 2 1 3 3 3 3 AAA domain AAA_25 PF13481.1 KLO19974.1 - 1e-07 31.5 0.0 0.016 14.5 0.0 2.9 3 0 0 3 3 3 2 AAA domain AAA_16 PF13191.1 KLO19974.1 - 2e-06 27.9 1.6 0.012 15.6 0.2 2.4 2 0 0 2 2 2 2 AAA ATPase domain AAA_23 PF13476.1 KLO19974.1 - 7.5e-06 26.4 1.4 0.00024 21.4 0.0 2.8 3 0 0 3 3 2 1 AAA domain AAA_29 PF13555.1 KLO19974.1 - 1.7e-05 24.2 0.1 0.1 12.1 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain T2SE PF00437.15 KLO19974.1 - 7.7e-05 21.7 0.0 0.014 14.3 0.0 2.4 2 0 0 2 2 2 1 Type II/IV secretion system protein FtsK_SpoIIIE PF01580.13 KLO19974.1 - 9.4e-05 21.9 0.3 0.13 11.6 0.0 2.3 2 0 0 2 2 2 2 FtsK/SpoIIIE family MobB PF03205.9 KLO19974.1 - 9.9e-05 22.0 0.3 0.36 10.5 0.0 2.6 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B Miro PF08477.8 KLO19974.1 - 0.00016 22.1 0.1 0.5 10.8 0.0 3.2 3 0 0 3 3 2 1 Miro-like protein DUF87 PF01935.12 KLO19974.1 - 0.00035 20.4 0.2 0.065 13.0 0.1 2.5 2 0 0 2 2 2 1 Domain of unknown function DUF87 AAA_17 PF13207.1 KLO19974.1 - 0.00045 21.0 0.1 1.5 9.6 0.0 3.5 3 1 0 3 3 2 1 AAA domain MMR_HSR1 PF01926.18 KLO19974.1 - 0.0013 18.6 0.7 0.93 9.4 0.0 3.0 3 0 0 3 3 2 1 50S ribosome-binding GTPase AAA_10 PF12846.2 KLO19974.1 - 0.0014 18.1 0.9 1.9 7.8 0.0 2.9 2 1 0 3 3 3 2 AAA-like domain AAA_18 PF13238.1 KLO19974.1 - 0.0024 18.1 0.3 3.1 8.1 0.0 3.4 3 0 0 3 3 3 1 AAA domain Arch_ATPase PF01637.13 KLO19974.1 - 0.0026 17.5 0.0 0.53 9.9 0.0 2.6 2 0 0 2 2 2 1 Archaeal ATPase DUF258 PF03193.11 KLO19974.1 - 0.0045 16.1 0.1 2.3 7.4 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF258 Adeno_IVa2 PF02456.10 KLO19974.1 - 0.0092 14.6 0.1 0.049 12.2 0.0 2.0 2 0 0 2 2 2 1 Adenovirus IVa2 protein AAA_5 PF07728.9 KLO19974.1 - 0.012 15.3 0.1 7.6 6.2 0.0 3.3 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 KLO19974.1 - 0.013 15.6 2.9 1.1 9.4 0.0 3.3 2 1 0 2 2 2 0 AAA domain IstB_IS21 PF01695.12 KLO19974.1 - 0.016 14.6 0.0 5.3 6.4 0.0 2.9 3 0 0 3 3 2 0 IstB-like ATP binding protein Dynamin_N PF00350.18 KLO19974.1 - 0.03 14.1 1.8 1.7 8.4 0.0 2.7 2 0 0 2 2 2 0 Dynamin family AAA_15 PF13175.1 KLO19974.1 - 0.053 12.5 0.0 0.11 11.5 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain Pox_A32 PF04665.7 KLO19974.1 - 0.062 12.5 0.6 6.5 5.9 0.1 2.4 2 0 0 2 2 2 0 Poxvirus A32 protein AAA_19 PF13245.1 KLO19974.1 - 0.073 12.8 0.0 4.6 7.0 0.0 3.0 2 0 0 2 2 2 0 Part of AAA domain NACHT PF05729.7 KLO19974.1 - 0.081 12.5 0.1 4.9 6.7 0.1 2.5 2 0 0 2 2 2 0 NACHT domain AAA PF00004.24 KLO19974.1 - 0.083 13.0 0.4 2.1 8.5 0.0 3.2 4 0 0 4 4 2 0 ATPase family associated with various cellular activities (AAA) Zeta_toxin PF06414.7 KLO19974.1 - 0.098 11.7 0.0 4.5 6.3 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin RNA_helicase PF00910.17 KLO19974.1 - 0.21 11.7 0.9 32 4.7 0.0 3.1 3 0 0 3 3 2 0 RNA helicase RRM_1 PF00076.17 KLO19975.1 - 4.4e-15 55.0 0.1 6.6e-15 54.5 0.1 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KLO19975.1 - 3.4e-11 42.9 0.0 5.2e-11 42.3 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KLO19975.1 - 7.2e-09 35.3 0.1 1.1e-08 34.8 0.1 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCHC PF00098.18 KLO19975.1 - 3.6e-07 29.8 3.2 6.1e-07 29.0 2.2 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_3 PF13917.1 KLO19975.1 - 0.00076 19.1 0.5 0.0018 17.9 0.4 1.6 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_4 PF14392.1 KLO19975.1 - 0.0037 16.8 0.2 0.0037 16.8 0.1 2.0 2 0 0 2 2 2 1 Zinc knuckle RRM_3 PF08777.6 KLO19975.1 - 0.021 14.6 0.1 0.04 13.7 0.0 1.4 1 0 0 1 1 1 0 RNA binding motif zf-CCHC_5 PF14787.1 KLO19975.1 - 0.042 13.3 3.8 0.04 13.4 1.0 2.2 2 0 0 2 2 2 0 GAG-polyprotein viral zinc-finger zf-CCHC_6 PF15288.1 KLO19975.1 - 0.68 9.6 4.1 1.6 8.4 2.8 1.6 1 0 0 1 1 1 0 Zinc knuckle Glyco_hydro_72 PF03198.9 KLO19976.1 - 3.2e-88 295.7 0.0 5.3e-88 295.0 0.0 1.3 1 0 0 1 1 1 1 Glucanosyltransferase X8 PF07983.8 KLO19976.1 - 4.9e-19 68.5 0.5 1.2e-18 67.3 0.3 1.7 1 0 0 1 1 1 1 X8 domain SUR7 PF06687.7 KLO19977.1 - 2.9e-17 62.9 11.2 3.9e-17 62.5 7.8 1.2 1 0 0 1 1 1 1 SUR7/PalI family Claudin_2 PF13903.1 KLO19977.1 - 0.00019 21.1 7.0 0.00019 21.1 4.8 2.0 2 0 0 2 2 2 1 PMP-22/EMP/MP20/Claudin tight junction Trp_oprn_chp PF09534.5 KLO19977.1 - 0.09 12.3 1.1 0.18 11.3 0.8 1.5 1 0 0 1 1 1 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) MRAP PF15183.1 KLO19977.1 - 2.6 7.6 5.2 27 4.4 1.1 2.6 2 0 0 2 2 2 0 Melanocortin-2 receptor accessory protein family DUF2231 PF09990.4 KLO19977.1 - 3.8 7.9 15.0 0.64 10.3 6.7 2.4 2 1 1 3 3 3 0 Predicted membrane protein (DUF2231) Glyco_transf_28 PF03033.15 KLO19978.1 - 2.5e-26 92.0 0.0 6.2e-26 90.8 0.0 1.7 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain GRAM PF02893.15 KLO19978.1 - 1.1e-20 72.9 3.3 8.8e-11 41.1 0.2 3.5 3 0 0 3 3 3 3 GRAM domain PH PF00169.24 KLO19978.1 - 9.4e-17 61.1 2.3 4.1e-13 49.4 0.3 3.3 3 0 0 3 3 3 2 PH domain UDPGT PF00201.13 KLO19978.1 - 1.5e-06 27.0 0.0 4.9e-06 25.3 0.0 1.7 1 1 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase PH_11 PF15413.1 KLO19978.1 - 1e-05 25.7 2.2 0.00026 21.2 1.5 2.7 1 1 0 1 1 1 1 Pleckstrin homology domain PH_8 PF15409.1 KLO19978.1 - 8.1e-05 22.6 0.2 0.0002 21.3 0.1 1.7 1 0 0 1 1 1 1 Pleckstrin homology domain PH_3 PF14593.1 KLO19978.1 - 0.0012 18.7 0.2 0.0024 17.7 0.1 1.5 1 0 0 1 1 1 1 PH domain PH_6 PF15406.1 KLO19978.1 - 0.0024 17.8 0.0 0.0077 16.2 0.0 1.9 1 0 0 1 1 1 1 Pleckstrin homology domain PH_BEACH PF14844.1 KLO19978.1 - 0.055 13.3 0.0 3.2 7.6 0.0 2.6 2 0 0 2 2 2 0 PH domain associated with Beige/BEACH Josephin PF02099.12 KLO19978.1 - 0.23 11.0 0.6 1 8.9 0.0 2.2 2 0 0 2 2 2 0 Josephin DIOX_N PF14226.1 KLO19979.1 - 4.1e-07 30.5 0.0 1.2e-06 29.0 0.0 1.7 2 0 0 2 2 2 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 KLO19979.1 - 0.0027 17.9 0.0 0.0042 17.3 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Pkinase PF00069.20 KLO19980.1 - 1.7e-61 207.6 0.0 8.5e-61 205.3 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KLO19980.1 - 3.2e-34 118.1 0.1 2.4e-26 92.3 0.1 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 KLO19980.1 - 1e-05 24.6 0.6 0.00018 20.6 0.4 2.4 1 1 0 1 1 1 1 Kinase-like APH PF01636.18 KLO19980.1 - 0.00031 20.5 1.3 0.0022 17.7 0.0 2.6 2 0 0 2 2 2 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 KLO19980.1 - 0.0063 15.3 0.2 0.02 13.7 0.0 1.8 2 0 0 2 2 2 1 Seadornavirus VP7 adh_short PF00106.20 KLO19981.1 - 5.6e-15 55.6 1.7 1.2e-14 54.5 1.2 1.6 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KLO19981.1 - 4.8e-09 36.3 0.0 6.5e-09 35.9 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 KLO19981.1 - 4.3e-06 26.3 0.1 8e-06 25.4 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.5 KLO19981.1 - 2.6e-05 23.9 0.1 3.5e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 KR domain TGS PF02824.16 KLO19982.1 - 7.2e-21 73.7 0.0 1.2e-20 73.0 0.0 1.4 1 0 0 1 1 1 1 TGS domain MMR_HSR1 PF01926.18 KLO19982.1 - 1.7e-17 63.3 0.0 4.3e-17 62.1 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 KLO19982.1 - 1.7e-10 40.4 0.0 3.1e-10 39.5 0.0 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.18 KLO19982.1 - 9.7e-05 22.2 0.2 0.048 13.4 0.0 2.6 1 1 1 2 2 2 2 Dynamin family Miro PF08477.8 KLO19982.1 - 0.00019 21.9 0.1 0.0008 19.8 0.0 2.1 2 1 0 2 2 2 1 Miro-like protein ArgK PF03308.11 KLO19982.1 - 0.033 12.9 0.2 0.12 11.0 0.0 2.0 1 1 1 2 2 2 0 ArgK protein Lactamase_B_2 PF12706.2 KLO19983.1 - 2.4e-10 40.3 0.0 4.3e-10 39.4 0.0 1.3 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 KLO19983.1 - 4.7e-08 32.9 0.0 7.6e-08 32.2 0.0 1.3 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_3 PF13483.1 KLO19983.1 - 0.025 14.3 0.0 0.047 13.3 0.0 1.4 1 0 0 1 1 1 0 Beta-lactamase superfamily domain PRELI PF04707.9 KLO19984.1 - 6.4e-32 110.2 0.0 8.1e-32 109.9 0.0 1.1 1 0 0 1 1 1 1 PRELI-like family RIC1 PF07064.8 KLO19985.1 - 5.6e-76 255.4 1.1 8e-76 254.8 0.7 1.2 1 0 0 1 1 1 1 RIC1 FAM176 PF14851.1 KLO19986.1 - 0.0011 18.7 2.8 0.14 11.8 2.9 2.5 2 0 0 2 2 2 1 FAM176 family Myc_N PF01056.13 KLO19986.1 - 0.0025 17.0 6.4 0.0025 17.0 4.4 2.0 2 0 0 2 2 2 1 Myc amino-terminal region Senescence PF06911.7 KLO19986.1 - 0.0031 17.2 3.2 0.0055 16.4 2.2 1.3 1 0 0 1 1 1 1 Senescence-associated protein Nucleoplasmin PF03066.10 KLO19986.1 - 0.024 14.1 9.8 0.041 13.3 6.8 1.3 1 0 0 1 1 1 0 Nucleoplasmin PBP1_TM PF14812.1 KLO19986.1 - 0.059 13.6 15.1 0.12 12.6 10.5 1.5 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Sigma70_ner PF04546.8 KLO19986.1 - 0.1 12.1 9.6 0.16 11.5 6.7 1.2 1 0 0 1 1 1 0 Sigma-70, non-essential region RXT2_N PF08595.6 KLO19986.1 - 0.16 11.7 6.1 0.28 10.9 4.2 1.3 1 0 0 1 1 1 0 RXT2-like, N-terminal Daxx PF03344.10 KLO19986.1 - 0.18 10.2 9.0 0.26 9.7 6.2 1.2 1 0 0 1 1 1 0 Daxx Family Tom22 PF04281.8 KLO19986.1 - 0.18 11.3 6.8 0.38 10.2 4.7 1.6 1 0 0 1 1 1 0 Mitochondrial import receptor subunit Tom22 NOA36 PF06524.7 KLO19986.1 - 0.22 10.7 10.2 0.33 10.1 7.1 1.2 1 0 0 1 1 1 0 NOA36 protein Cwf_Cwc_15 PF04889.7 KLO19986.1 - 0.22 11.1 10.2 0.35 10.5 7.1 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Senescence_reg PF04520.8 KLO19986.1 - 0.46 10.9 8.4 0.95 9.9 5.8 1.4 1 0 0 1 1 1 0 Senescence regulator Nop14 PF04147.7 KLO19986.1 - 0.82 7.5 10.1 1.1 7.0 7.0 1.1 1 0 0 1 1 1 0 Nop14-like family ORC6 PF05460.8 KLO19986.1 - 4.3 6.3 10.4 6.7 5.7 7.2 1.2 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) CENP-B_dimeris PF09026.5 KLO19986.1 - 6.6 7.0 15.9 16 5.8 11.0 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain B-block_TFIIIC PF04182.7 KLO19987.1 - 5.8e-13 48.4 0.3 4.5e-11 42.4 0.1 3.7 4 0 0 4 4 4 1 B-block binding subunit of TFIIIC RPA_C PF08784.6 KLO19987.1 - 0.00083 19.7 0.1 9.5 6.7 0.0 4.8 4 0 0 4 4 4 2 Replication protein A C terminal HTH_27 PF13463.1 KLO19987.1 - 0.023 14.9 0.1 0.33 11.3 0.0 3.1 3 0 0 3 3 3 0 Winged helix DNA-binding domain MarR PF01047.17 KLO19987.1 - 0.051 13.2 0.1 0.38 10.4 0.0 2.7 2 0 0 2 2 2 0 MarR family PRELI PF04707.9 KLO19988.1 - 8.8e-46 155.3 0.0 1e-45 155.1 0.0 1.0 1 0 0 1 1 1 1 PRELI-like family DEAD PF00270.24 KLO19989.1 - 2.8e-38 131.0 0.0 5.7e-38 130.0 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KLO19989.1 - 1.1e-23 82.9 0.1 2.1e-23 81.9 0.1 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 KLO19989.1 - 4.1e-06 26.7 0.0 7.5e-06 25.9 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_19 PF13245.1 KLO19989.1 - 0.0097 15.6 0.1 0.066 12.9 0.0 2.4 3 0 0 3 3 3 1 Part of AAA domain AAA_22 PF13401.1 KLO19989.1 - 0.055 13.6 0.7 0.18 11.9 0.5 1.8 1 1 0 1 1 1 0 AAA domain CMS1 PF14617.1 KLO19989.1 - 0.066 12.2 0.0 0.15 11.0 0.0 1.5 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit Glyco_hydro_43 PF04616.9 KLO19990.1 - 4e-18 65.4 4.4 7.4e-18 64.6 3.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 CBM_6 PF03422.10 KLO19990.1 - 0.019 15.1 6.1 0.019 15.1 4.2 2.3 2 0 0 2 2 2 0 Carbohydrate binding module (family 6) DEAD PF00270.24 KLO19991.1 - 4.2e-36 123.9 0.1 7.9e-36 123.0 0.1 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KLO19991.1 - 1.7e-24 85.4 0.0 7.8e-24 83.3 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 KLO19991.1 - 3.4e-05 23.7 0.0 7.2e-05 22.7 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit HATPase_c PF02518.21 KLO19992.1 - 2.8e-28 97.8 0.2 6.7e-28 96.6 0.1 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 KLO19992.1 - 6.1e-20 71.2 0.0 5.1e-19 68.3 0.0 2.4 2 0 0 2 2 2 1 Response regulator receiver domain AAA_16 PF13191.1 KLO19992.1 - 1.1e-15 58.1 2.9 3.7e-15 56.4 0.9 2.7 2 0 0 2 2 2 1 AAA ATPase domain HisKA PF00512.20 KLO19992.1 - 1.7e-14 53.5 0.0 1.2e-13 50.8 0.0 2.6 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain Pkinase PF00069.20 KLO19992.1 - 2.4e-10 39.9 0.0 7.3e-10 38.4 0.0 1.8 1 0 0 1 1 1 1 Protein kinase domain GAF_3 PF13492.1 KLO19992.1 - 2.9e-08 33.8 0.1 6.2e-08 32.8 0.1 1.6 1 0 0 1 1 1 1 GAF domain GAF_2 PF13185.1 KLO19992.1 - 1.2e-07 32.3 0.0 4.5e-07 30.4 0.0 2.1 1 0 0 1 1 1 1 GAF domain Pkinase_Tyr PF07714.12 KLO19992.1 - 3.3e-07 29.6 0.0 6.4e-07 28.7 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase HATPase_c_3 PF13589.1 KLO19992.1 - 0.00021 20.9 0.0 0.00069 19.2 0.0 1.9 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Guanylate_kin PF00625.16 KLO19992.1 - 0.022 14.2 0.8 0.66 9.3 0.3 2.4 2 0 0 2 2 2 0 Guanylate kinase AAA_22 PF13401.1 KLO19992.1 - 0.026 14.6 2.2 0.87 9.7 0.3 3.7 2 1 0 2 2 2 0 AAA domain AAA_30 PF13604.1 KLO19992.1 - 0.051 13.1 0.1 0.14 11.7 0.0 1.8 1 0 0 1 1 1 0 AAA domain Yae1_N PF09811.4 KLO19994.1 - 0.009 15.5 1.1 0.022 14.2 0.8 1.7 1 0 0 1 1 1 1 Essential protein Yae1, N terminal E1_dh PF00676.15 KLO19994.1 - 0.026 13.2 0.0 0.046 12.4 0.0 1.3 1 0 0 1 1 1 0 Dehydrogenase E1 component IncA PF04156.9 KLO19994.1 - 3.7 7.0 21.9 0.032 13.8 9.7 1.5 2 0 0 2 2 2 0 IncA protein NTP_transferase PF00483.18 KLO19995.1 - 7e-42 143.4 0.0 1.4e-41 142.4 0.0 1.5 2 0 0 2 2 2 1 Nucleotidyl transferase NTP_transf_3 PF12804.2 KLO19995.1 - 1.5e-07 31.6 0.1 2.7e-07 30.7 0.0 1.6 1 0 0 1 1 1 1 MobA-like NTP transferase domain MannoseP_isomer PF01050.13 KLO19995.1 - 3.1e-05 23.6 0.1 5.4e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 Mannose-6-phosphate isomerase CCDC92 PF14916.1 KLO19995.1 - 0.041 13.4 0.9 0.47 10.0 0.1 2.2 2 0 0 2 2 2 0 Coiled-coil domain of unknown function Las1 PF04031.8 KLO19996.1 - 2.5e-46 157.1 0.1 6.4e-46 155.8 0.0 1.7 2 0 0 2 2 2 1 Las1-like DUF2933 PF11666.3 KLO19997.1 - 3.5 7.2 0.0 3.5 7.2 0.0 3.7 4 0 0 4 4 4 0 Protein of unknown function (DUF2933) Claudin_2 PF13903.1 KLO19997.1 - 6.3 6.4 16.0 0.11 12.1 4.3 2.6 1 1 2 3 3 3 0 PMP-22/EMP/MP20/Claudin tight junction CsbD PF05532.7 KLO19999.1 - 5.5e-14 51.5 13.9 4.5e-08 32.6 2.2 2.1 1 1 1 2 2 2 2 CsbD-like Beta-lactamase2 PF13354.1 KLO19999.1 - 0.28 10.6 2.0 0.35 10.2 0.5 1.6 1 1 1 2 2 2 0 Beta-lactamase enzyme family Pkinase PF00069.20 KLO20000.1 - 0.0041 16.2 0.0 0.0091 15.1 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KLO20000.1 - 0.036 13.1 0.1 0.098 11.7 0.0 1.7 2 0 0 2 2 2 0 Protein tyrosine kinase p450 PF00067.17 KLO20001.1 - 1.2e-53 182.3 0.0 1.5e-53 182.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Dicistro_VP4 PF11492.3 KLO20001.1 - 0.27 11.2 1.8 17 5.5 0.3 2.5 2 0 0 2 2 2 0 Cricket paralysis virus, VP4 p450 PF00067.17 KLO20002.1 - 5.1e-46 157.1 0.0 6.1e-46 156.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Pkinase PF00069.20 KLO20003.1 - 2.9e-06 26.6 0.0 6.9e-06 25.3 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KLO20003.1 - 0.013 14.5 0.0 0.035 13.1 0.0 1.7 2 0 0 2 2 2 0 Protein tyrosine kinase Dicty_CTDC PF00526.13 KLO20005.1 - 1.2 9.0 4.5 2.4 8.0 3.1 1.5 1 0 0 1 1 1 0 Dictyostelium (slime mold) repeat Flavoprotein PF02441.14 KLO20006.1 - 1.7e-41 140.8 0.0 2.1e-41 140.5 0.0 1.1 1 0 0 1 1 1 1 Flavoprotein DUF498 PF04430.9 KLO20006.1 - 0.057 12.9 0.0 0.096 12.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF498/DUF598) CBM_19 PF03427.8 KLO20007.1 - 0.0028 17.3 3.7 0.0028 17.3 2.5 3.7 2 1 1 4 4 4 1 Carbohydrate binding domain (family 19) DUF447 PF04289.7 KLO20007.1 - 0.13 11.8 0.2 0.23 10.9 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF447) CBM_14 PF01607.19 KLO20007.1 - 0.18 11.7 3.1 0.21 11.5 1.1 1.9 2 0 0 2 2 2 0 Chitin binding Peritrophin-A domain Macoilin PF09726.4 KLO20007.1 - 5.7 5.0 11.7 6.8 4.8 8.1 1.1 1 0 0 1 1 1 0 Transmembrane protein MAP65_ASE1 PF03999.7 KLO20007.1 - 7.6 5.0 10.0 10 4.5 6.9 1.1 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) HAD_2 PF13419.1 KLO20008.1 - 4.9e-18 65.9 0.0 6.3e-18 65.6 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 KLO20008.1 - 8.9e-11 42.6 0.0 6e-09 36.6 0.0 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 KLO20008.1 - 8.5e-10 38.2 0.1 1.7e-09 37.2 0.1 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like HAD PF12710.2 KLO20008.1 - 0.00042 20.5 0.0 0.00076 19.6 0.0 1.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase DUF3639 PF12341.3 KLO20008.1 - 0.089 12.8 1.1 0.089 12.8 0.8 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3639) Pkinase PF00069.20 KLO20010.1 - 5.7e-34 117.4 0.0 8.1e-34 116.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KLO20010.1 - 9.4e-21 74.0 0.0 1.2e-20 73.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KLO20010.1 - 0.077 11.9 0.0 0.12 11.2 0.0 1.2 1 0 0 1 1 1 0 Kinase-like APH PF01636.18 KLO20010.1 - 0.15 11.7 1.2 0.6 9.7 0.0 2.0 1 1 1 2 2 2 0 Phosphotransferase enzyme family MOZ_SAS PF01853.13 KLO20011.1 - 6e-62 208.2 0.3 3.7e-60 202.4 0.1 2.2 2 0 0 2 2 2 2 MOZ/SAS family Pkinase PF00069.20 KLO20012.1 - 4.5e-62 209.5 0.1 6.3e-62 209.0 0.1 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KLO20012.1 - 2.9e-25 88.7 0.1 4.9e-25 88.0 0.1 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KLO20012.1 - 3.8e-07 29.3 0.0 7e-07 28.4 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 KLO20012.1 - 0.13 11.9 0.0 2.2 7.9 0.0 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family MaoC_dehydrat_N PF13452.1 KLO20013.1 - 0.14 11.9 0.1 0.23 11.2 0.0 1.2 1 0 0 1 1 1 0 N-terminal half of MaoC dehydratase Ribosomal_L19e PF01280.15 KLO20014.1 - 4.1e-61 205.0 10.9 4.1e-61 205.0 7.6 1.9 1 1 1 2 2 2 1 Ribosomal protein L19e S4 PF01479.20 KLO20014.1 - 0.0032 16.8 0.0 0.011 15.1 0.0 1.9 1 0 0 1 1 1 1 S4 domain AAA PF00004.24 KLO20015.1 - 1.6e-42 144.7 0.0 2.9e-42 144.0 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.5 KLO20015.1 - 6.5e-27 93.2 0.1 3.8e-26 90.7 0.1 2.2 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain MIT PF04212.13 KLO20015.1 - 9.9e-21 73.4 5.0 9.9e-21 73.4 3.4 2.5 3 0 0 3 3 3 1 MIT (microtubule interacting and transport) domain AAA_17 PF13207.1 KLO20015.1 - 2.6e-06 28.2 0.5 2.3e-05 25.1 0.0 2.8 2 2 0 2 2 2 1 AAA domain AAA_22 PF13401.1 KLO20015.1 - 3.2e-06 27.2 0.1 0.0007 19.7 0.0 2.7 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.12 KLO20015.1 - 1.7e-05 24.3 0.0 4.7e-05 22.8 0.0 1.7 2 0 0 2 2 1 1 IstB-like ATP binding protein AAA_14 PF13173.1 KLO20015.1 - 2.1e-05 24.4 0.0 7.8e-05 22.5 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.9 KLO20015.1 - 2.2e-05 24.2 0.0 9.3e-05 22.1 0.0 2.1 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.7 KLO20015.1 - 4.3e-05 22.6 0.0 7.5e-05 21.8 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus TIP49 PF06068.8 KLO20015.1 - 0.00011 21.1 0.0 0.00017 20.4 0.0 1.3 1 0 0 1 1 1 1 TIP49 C-terminus DUF815 PF05673.8 KLO20015.1 - 0.00013 21.0 0.0 0.0008 18.4 0.0 2.0 1 1 1 2 2 2 1 Protein of unknown function (DUF815) RNA_helicase PF00910.17 KLO20015.1 - 0.00018 21.6 0.0 0.007 16.5 0.0 2.8 3 0 0 3 3 2 1 RNA helicase AAA_25 PF13481.1 KLO20015.1 - 0.00022 20.6 0.1 0.2 11.0 0.1 2.5 1 1 1 2 2 2 2 AAA domain AAA_33 PF13671.1 KLO20015.1 - 0.00024 20.9 0.0 0.001 18.9 0.0 2.1 3 0 0 3 3 1 1 AAA domain AAA_16 PF13191.1 KLO20015.1 - 0.00025 21.0 0.0 0.0018 18.2 0.0 2.2 1 1 1 2 2 2 1 AAA ATPase domain AAA_2 PF07724.9 KLO20015.1 - 0.00064 19.6 0.0 0.003 17.5 0.0 2.0 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_18 PF13238.1 KLO20015.1 - 0.0043 17.3 0.2 0.02 15.2 0.0 2.2 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.7 KLO20015.1 - 0.0089 15.1 0.1 0.18 10.8 0.1 2.6 1 1 0 1 1 1 1 Zeta toxin AAA_24 PF13479.1 KLO20015.1 - 0.014 14.9 0.0 0.027 14.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain Arch_ATPase PF01637.13 KLO20015.1 - 0.023 14.4 0.9 0.53 9.9 0.0 2.6 2 1 1 3 3 3 0 Archaeal ATPase ResIII PF04851.10 KLO20015.1 - 0.023 14.5 0.0 0.09 12.6 0.0 1.8 1 1 1 2 2 2 0 Type III restriction enzyme, res subunit PhoH PF02562.11 KLO20015.1 - 0.025 13.7 0.0 0.05 12.8 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein AAA_19 PF13245.1 KLO20015.1 - 0.027 14.2 0.0 0.067 12.9 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain Mg_chelatase PF01078.16 KLO20015.1 - 0.031 13.4 0.0 0.062 12.4 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI NACHT PF05729.7 KLO20015.1 - 0.041 13.5 0.0 0.47 10.1 0.0 2.3 1 1 0 1 1 1 0 NACHT domain KaiC PF06745.8 KLO20015.1 - 0.044 12.9 0.2 6.3 5.8 0.0 2.7 2 1 1 3 3 3 0 KaiC Parvo_NS1 PF01057.12 KLO20015.1 - 0.05 12.4 0.0 0.097 11.5 0.0 1.4 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_28 PF13521.1 KLO20015.1 - 0.081 12.8 0.0 0.23 11.4 0.0 1.9 1 0 0 1 1 1 0 AAA domain Bac_DnaA PF00308.13 KLO20015.1 - 0.087 12.4 0.0 0.4 10.3 0.0 2.1 2 1 0 2 2 1 0 Bacterial dnaA protein Torsin PF06309.6 KLO20015.1 - 0.096 12.5 0.0 0.2 11.5 0.0 1.5 1 0 0 1 1 1 0 Torsin Sigma54_activat PF00158.21 KLO20015.1 - 0.13 11.7 0.0 0.4 10.1 0.0 1.9 1 1 0 1 1 1 0 Sigma-54 interaction domain Sigma54_activ_2 PF14532.1 KLO20015.1 - 0.16 12.0 0.0 0.4 10.7 0.0 1.7 1 0 0 1 1 1 0 Sigma-54 interaction domain DUF4407 PF14362.1 KLO20015.1 - 0.16 10.9 2.1 0.25 10.2 1.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) AAA_21 PF13304.1 KLO20015.1 - 0.23 11.3 1.1 2.7 7.8 0.0 2.7 2 1 1 3 3 3 0 AAA domain Abhydrolase_1 PF00561.15 KLO20016.1 - 5.2e-35 121.0 0.0 4e-34 118.1 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 KLO20016.1 - 1.2e-08 35.1 1.0 3.2e-08 33.7 0.7 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_4 PF08386.5 KLO20016.1 - 0.045 13.6 0.0 0.12 12.3 0.0 1.7 1 0 0 1 1 1 0 TAP-like protein DHC_N1 PF08385.7 KLO20017.1 - 5e-191 636.0 12.9 5.7e-191 635.8 1.9 2.5 3 0 0 3 3 3 2 Dynein heavy chain, N-terminal region 1 adh_short PF00106.20 KLO20018.1 - 8.4e-18 64.8 5.1 2.4e-13 50.3 1.8 2.1 2 0 0 2 2 2 2 short chain dehydrogenase KR PF08659.5 KLO20018.1 - 6.5e-11 42.2 1.7 6.5e-11 42.2 1.2 2.0 2 0 0 2 2 2 1 KR domain adh_short_C2 PF13561.1 KLO20018.1 - 0.00038 20.3 0.1 0.035 13.8 0.0 2.3 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 KLO20018.1 - 0.021 14.8 0.7 0.044 13.8 0.4 1.6 1 1 0 1 1 1 0 NADH(P)-binding Eno-Rase_NADH_b PF12242.3 KLO20018.1 - 0.054 13.2 0.0 0.11 12.2 0.0 1.5 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase THF_DHG_CYH_C PF02882.14 KLO20018.1 - 0.07 12.2 0.0 0.11 11.5 0.0 1.2 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain DUF2193 PF09959.4 KLO20019.1 - 0.026 12.7 0.6 0.025 12.8 0.4 1.0 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2193) DUF3359 PF11839.3 KLO20019.1 - 0.42 10.9 7.7 0.49 10.7 5.2 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3359) DUF883 PF05957.8 KLO20019.1 - 1.1 9.7 7.4 0.49 10.8 2.9 2.0 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) DivIVA PF05103.8 KLO20019.1 - 6.1 6.9 9.5 4.4 7.3 5.4 1.5 1 1 0 1 1 1 0 DivIVA protein zf-MYND PF01753.13 KLO20020.1 - 7.2e-08 32.1 15.0 1.4e-07 31.2 10.4 1.5 1 0 0 1 1 1 1 MYND finger Caerin_1 PF07440.7 KLO20020.1 - 0.13 12.1 0.1 0.23 11.3 0.1 1.4 1 0 0 1 1 1 0 Caerin 1 protein DLH PF01738.13 KLO20021.1 - 1.8e-11 43.7 0.0 2.2e-11 43.4 0.0 1.0 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 KLO20021.1 - 0.012 15.3 0.0 0.02 14.6 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family F-box-like PF12937.2 KLO20022.1 - 0.00018 21.1 0.7 0.00042 19.9 0.5 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KLO20022.1 - 0.11 12.1 0.1 0.32 10.7 0.0 1.8 2 0 0 2 2 2 0 F-box domain Prenylcys_lyase PF07156.9 KLO20023.1 - 4.1e-47 160.8 0.0 6.4e-47 160.2 0.0 1.2 1 0 0 1 1 1 1 Prenylcysteine lyase NAD_binding_8 PF13450.1 KLO20023.1 - 4.1e-09 36.3 0.2 1.2e-08 34.7 0.0 1.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.19 KLO20023.1 - 7.2e-05 22.0 0.0 0.0019 17.3 0.0 2.1 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase DAO PF01266.19 KLO20023.1 - 0.0049 15.8 0.6 1.5 7.6 0.6 2.4 3 0 0 3 3 3 2 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 KLO20023.1 - 0.014 15.1 0.0 0.05 13.3 0.0 1.9 2 0 0 2 2 2 0 FAD-NAD(P)-binding Ammonium_transp PF00909.16 KLO20024.1 - 7.6e-119 396.7 17.8 8.9e-119 396.5 12.3 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family SieB PF14163.1 KLO20024.1 - 1.3 8.5 6.2 15 5.1 0.0 2.2 2 0 0 2 2 2 0 Superinfection exclusion protein B CTP_transf_2 PF01467.21 KLO20025.1 - 1.2e-10 41.6 0.0 1.6e-07 31.5 0.0 3.0 2 1 0 2 2 2 2 Cytidylyltransferase Proteasome PF00227.21 KLO20027.1 - 2.3e-37 128.1 0.0 2.6e-37 127.9 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit DUF4448 PF14610.1 KLO20028.1 - 0.0019 17.7 0.1 0.0037 16.7 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) Sarcoglycan_2 PF05510.8 KLO20028.1 - 0.016 13.5 0.0 0.023 12.9 0.0 1.2 1 0 0 1 1 1 0 Sarcoglycan alpha/epsilon SKG6 PF08693.5 KLO20028.1 - 0.034 13.4 0.4 0.099 11.9 0.3 1.8 1 0 0 1 1 1 0 Transmembrane alpha-helix domain DUF155 PF02582.9 KLO20029.1 - 6e-57 192.3 0.3 1.2e-56 191.3 0.2 1.5 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 Cytomega_UL20A PF05984.7 KLO20030.1 - 0.092 12.9 0.2 3 8.0 0.0 2.8 2 0 0 2 2 2 0 Cytomegalovirus UL20A protein GHMP_kinases_N PF00288.21 KLO20031.1 - 4.4e-12 45.8 0.7 7.8e-12 45.0 0.5 1.4 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.8 KLO20031.1 - 0.014 15.5 0.0 0.036 14.2 0.0 1.7 1 0 0 1 1 1 0 GHMP kinases C terminal Romo1 PF10247.4 KLO20033.1 - 2e-22 79.1 8.4 2.7e-22 78.7 5.8 1.2 1 0 0 1 1 1 1 Reactive mitochondrial oxygen species modulator 1 Pex2_Pex12 PF04757.9 KLO20034.1 - 2.5e-29 102.3 1.8 3.7e-29 101.7 1.3 1.2 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4_3 PF13920.1 KLO20034.1 - 8.4e-10 38.1 5.2 1.2e-09 37.6 3.6 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KLO20034.1 - 1.5e-09 37.5 8.0 2.3e-09 36.9 5.5 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 KLO20034.1 - 2e-09 37.3 7.7 3.1e-09 36.7 5.3 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 KLO20034.1 - 9.5e-09 34.7 7.0 1.4e-08 34.1 4.9 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KLO20034.1 - 1.2e-07 31.3 6.6 1.9e-07 30.6 4.6 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 KLO20034.1 - 6.3e-05 22.7 7.1 0.00011 21.9 4.9 1.4 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.2 KLO20034.1 - 6.4e-05 22.9 3.3 0.00011 22.1 2.3 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_UBOX PF13445.1 KLO20034.1 - 0.00078 19.1 2.0 0.0011 18.6 0.7 1.8 1 1 0 1 1 1 1 RING-type zinc-finger zf-Apc11 PF12861.2 KLO20034.1 - 0.0044 16.8 1.5 0.0075 16.0 1.0 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger TerY-C PF15616.1 KLO20034.1 - 0.0055 16.6 1.5 0.0097 15.8 1.1 1.3 1 0 0 1 1 1 1 TerY-C metal binding domain zf-RING_4 PF14570.1 KLO20034.1 - 0.04 13.5 5.7 0.074 12.6 3.9 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Prok-RING_4 PF14447.1 KLO20034.1 - 0.066 12.7 2.0 0.14 11.7 1.4 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 IBR PF01485.16 KLO20034.1 - 9.6 6.1 9.3 13 5.7 5.7 1.8 1 1 0 1 1 1 0 IBR domain Dynein_heavy PF03028.10 KLO20035.1 - 2.1e-183 611.1 0.0 2.1e-183 611.1 0.0 2.0 2 0 0 2 2 1 1 Dynein heavy chain and region D6 of dynein motor DHC_N2 PF08393.8 KLO20035.1 - 1.4e-127 425.5 7.4 1.4e-127 425.5 5.2 3.3 4 0 0 4 4 4 1 Dynein heavy chain, N-terminal region 2 AAA_6 PF12774.2 KLO20035.1 - 7.5e-79 264.4 0.0 1.2e-77 260.5 0.0 2.5 2 0 0 2 2 2 1 Hydrolytic ATP binding site of dynein motor region D1 AAA_8 PF12780.2 KLO20035.1 - 8.1e-47 159.4 0.2 1e-45 155.8 0.1 2.3 1 1 0 1 1 1 1 P-loop containing dynein motor region D4 AAA_9 PF12781.2 KLO20035.1 - 4.7e-45 153.1 0.1 2.7e-44 150.7 0.1 2.4 2 0 0 2 2 2 1 ATP-binding dynein motor region D5 MT PF12777.2 KLO20035.1 - 2.2e-42 145.0 5.9 4e-42 144.2 4.1 1.4 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA_5 PF07728.9 KLO20035.1 - 6.7e-29 100.3 0.0 1.5e-12 47.4 0.0 6.1 5 1 0 5 5 5 3 AAA domain (dynein-related subfamily) AAA_7 PF12775.2 KLO20035.1 - 3.4e-20 72.2 0.0 9.5e-20 70.7 0.0 1.8 2 0 0 2 2 1 1 P-loop containing dynein motor region D3 AAA PF00004.24 KLO20035.1 - 1.7e-14 54.1 0.0 0.0014 18.8 0.0 4.9 4 0 0 4 4 4 3 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 KLO20035.1 - 1.3e-13 51.2 0.0 0.015 15.4 0.0 5.3 4 0 0 4 4 4 3 AAA domain AAA_33 PF13671.1 KLO20035.1 - 1.9e-11 44.0 0.0 0.027 14.3 0.0 4.9 4 0 0 4 4 4 3 AAA domain AAA_16 PF13191.1 KLO20035.1 - 4.4e-10 39.8 0.0 0.14 12.1 0.0 6.3 6 0 0 6 6 5 2 AAA ATPase domain AAA_17 PF13207.1 KLO20035.1 - 1.1e-08 35.9 1.6 0.11 13.3 0.0 5.9 5 0 0 5 5 4 2 AAA domain AAA_18 PF13238.1 KLO20035.1 - 3.6e-08 33.7 0.1 0.016 15.5 0.0 5.4 5 0 0 5 5 5 1 AAA domain AAA_19 PF13245.1 KLO20035.1 - 1.1e-07 31.5 0.2 0.84 9.4 0.0 4.8 4 0 0 4 4 4 2 Part of AAA domain T2SE PF00437.15 KLO20035.1 - 2.3e-06 26.7 0.0 0.051 12.4 0.0 3.7 3 0 0 3 3 3 2 Type II/IV secretion system protein Mg_chelatase PF01078.16 KLO20035.1 - 2.5e-06 26.8 1.1 0.5 9.4 0.0 4.4 4 0 0 4 4 4 2 Magnesium chelatase, subunit ChlI AAA_14 PF13173.1 KLO20035.1 - 6e-06 26.1 0.0 0.5 10.2 0.0 4.9 5 0 0 5 5 3 2 AAA domain IstB_IS21 PF01695.12 KLO20035.1 - 2e-05 24.0 0.3 0.37 10.1 0.0 4.3 4 0 0 4 4 4 1 IstB-like ATP binding protein FtsK_SpoIIIE PF01580.13 KLO20035.1 - 8.4e-05 22.1 0.0 3.6 7.0 0.0 4.0 3 0 0 3 3 3 1 FtsK/SpoIIIE family AAA_29 PF13555.1 KLO20035.1 - 0.00088 18.7 0.0 0.67 9.5 0.0 3.5 3 0 0 3 3 3 1 P-loop containing region of AAA domain RNA_helicase PF00910.17 KLO20035.1 - 0.0064 16.6 0.0 21 5.3 0.0 4.4 4 0 0 4 4 4 0 RNA helicase AAA_25 PF13481.1 KLO20035.1 - 0.0074 15.7 0.2 2 7.7 0.0 4.1 4 0 0 4 4 3 1 AAA domain ResIII PF04851.10 KLO20035.1 - 0.015 15.1 2.8 3.3 7.5 0.0 3.9 5 0 0 5 5 3 0 Type III restriction enzyme, res subunit ApoO PF09769.4 KLO20035.1 - 0.017 14.8 2.4 0.57 9.8 0.8 3.1 3 0 0 3 3 2 0 Apolipoprotein O MobB PF03205.9 KLO20035.1 - 0.018 14.7 0.1 24 4.6 0.0 3.6 3 0 0 3 3 3 0 Molybdopterin guanine dinucleotide synthesis protein B ABC_tran PF00005.22 KLO20035.1 - 0.095 13.0 7.2 9.8 6.4 0.0 4.8 5 0 0 5 5 3 0 ABC transporter Med9 PF07544.8 KLO20036.1 - 4.9e-05 22.9 0.4 8.4e-05 22.2 0.2 1.5 1 1 0 1 1 1 1 RNA polymerase II transcription mediator complex subunit 9 ECM11 PF15463.1 KLO20036.1 - 0.046 14.0 0.1 0.18 12.0 0.0 1.8 2 0 0 2 2 2 0 Extracellular mutant protein 11 GST_N PF02798.15 KLO20037.1 - 7.8e-21 74.0 0.0 1.5e-20 73.1 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 KLO20037.1 - 3.8e-18 65.4 0.0 6.2e-18 64.7 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 KLO20037.1 - 1.6e-14 53.6 0.0 2.7e-14 52.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 KLO20037.1 - 2.3e-12 46.7 0.1 3.7e-12 46.0 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 KLO20037.1 - 8e-05 23.0 0.0 0.00011 22.6 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 KLO20037.1 - 0.00038 20.2 0.1 0.0017 18.2 0.0 2.0 2 1 0 2 2 2 1 Glutathione S-transferase, C-terminal domain Aldose_epim PF01263.15 KLO20038.1 - 9.9e-32 110.2 0.0 1.1e-31 110.0 0.0 1.0 1 0 0 1 1 1 1 Aldose 1-epimerase RINT1_TIP1 PF04437.8 KLO20039.1 - 5.7e-77 259.3 0.0 3.5e-75 253.4 0.0 2.3 2 0 0 2 2 2 2 RINT-1 / TIP-1 family DUF4200 PF13863.1 KLO20039.1 - 0.78 9.6 6.3 1.5 8.7 3.1 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF4200) Pro_CA PF00484.14 KLO20040.1 - 3.8e-29 101.6 0.0 4.4e-29 101.4 0.0 1.0 1 0 0 1 1 1 1 Carbonic anhydrase Glucosaminidase PF01832.15 KLO20040.1 - 0.087 12.9 0.0 0.15 12.1 0.0 1.4 2 0 0 2 2 2 0 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase NT5C PF06941.7 KLO20041.1 - 6.3e-14 51.9 0.3 1.8e-13 50.4 0.1 1.7 2 0 0 2 2 2 1 5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C) NT5C PF06941.7 KLO20042.1 - 1.4e-11 44.2 3.1 2.8e-11 43.2 0.2 2.4 2 1 0 2 2 2 1 5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C) HAD_2 PF13419.1 KLO20042.1 - 1.3e-05 25.5 0.2 3.3e-05 24.1 0.1 1.7 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase LNS2 PF08235.8 KLO20042.1 - 0.00061 19.3 0.0 0.00099 18.6 0.0 1.2 1 0 0 1 1 1 1 LNS2 (Lipin/Ned1/Smp2) Hydrolase PF00702.21 KLO20042.1 - 0.0027 18.1 0.0 0.0049 17.2 0.0 1.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Acid_phosphat_B PF03767.9 KLO20042.1 - 0.044 13.1 0.0 0.085 12.2 0.0 1.5 1 0 0 1 1 1 0 HAD superfamily, subfamily IIIB (Acid phosphatase) DUF3445 PF11927.3 KLO20043.1 - 7.8e-60 202.3 0.0 9.5e-60 202.0 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3445) ABC_membrane_2 PF06472.10 KLO20044.1 - 6.7e-87 291.1 1.2 1e-86 290.5 0.8 1.3 1 0 0 1 1 1 1 ABC transporter transmembrane region 2 ABC_tran PF00005.22 KLO20044.1 - 5e-17 62.4 0.0 1.2e-16 61.2 0.0 1.7 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 KLO20044.1 - 0.00035 20.6 0.0 0.00068 19.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_23 PF13476.1 KLO20044.1 - 0.019 15.3 0.5 0.037 14.3 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.1 KLO20044.1 - 0.037 13.5 0.0 0.095 12.2 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain SMC_N PF02463.14 KLO20044.1 - 0.04 13.1 0.0 0.11 11.7 0.0 1.7 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_16 PF13191.1 KLO20044.1 - 0.04 13.9 0.0 0.12 12.3 0.0 1.8 2 0 0 2 2 2 0 AAA ATPase domain DUF258 PF03193.11 KLO20044.1 - 0.092 11.9 0.0 0.17 11.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 Rad17 PF03215.10 KLO20044.1 - 0.16 10.6 0.1 0.26 9.9 0.0 1.2 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein PolyA_pol PF01743.15 KLO20045.1 - 1.4e-24 86.7 0.0 2.6e-24 85.8 0.0 1.5 1 0 0 1 1 1 1 Poly A polymerase head domain PolyA_pol_RNAbd PF12627.2 KLO20045.1 - 2.3e-08 33.4 0.0 4.7e-08 32.4 0.0 1.5 1 0 0 1 1 1 1 Probable RNA and SrmB- binding site of polymerase A tRNA_NucTran2_2 PF13735.1 KLO20045.1 - 0.013 15.3 0.0 0.028 14.2 0.0 1.5 1 0 0 1 1 1 0 tRNA nucleotidyltransferase domain 2 putative Abhydrolase_2 PF02230.11 KLO20046.1 - 1.3e-34 119.5 0.0 1.5e-34 119.3 0.0 1.0 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_5 PF12695.2 KLO20046.1 - 0.0019 17.9 0.0 0.0021 17.7 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KLO20046.1 - 0.075 12.8 0.1 0.09 12.6 0.1 1.4 1 1 0 1 1 1 0 Alpha/beta hydrolase family COX6A PF02046.10 KLO20047.1 - 1.5e-26 92.5 0.2 1.5e-26 92.5 0.2 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIa F-box PF00646.28 KLO20048.1 - 0.035 13.7 0.8 1.3 8.7 0.1 3.3 3 0 0 3 3 3 0 F-box domain PGP_phosphatase PF09419.5 KLO20050.1 - 2.1e-44 150.8 0.0 2.6e-44 150.5 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial PGP phosphatase DAO PF01266.19 KLO20051.1 - 3.4e-25 88.6 0.1 6.5e-25 87.7 0.0 1.4 1 1 0 1 1 1 1 FAD dependent oxidoreductase ApbA PF02558.11 KLO20051.1 - 0.00067 19.1 0.0 0.0016 17.8 0.0 1.6 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA Pyr_redox PF00070.22 KLO20051.1 - 0.0017 18.6 0.0 0.013 15.8 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.15 KLO20051.1 - 0.0028 17.7 0.0 0.0067 16.5 0.0 1.6 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NAD_binding_8 PF13450.1 KLO20051.1 - 0.0053 16.7 0.0 0.012 15.5 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_7 PF13241.1 KLO20051.1 - 0.019 15.2 0.0 0.04 14.1 0.0 1.6 1 0 0 1 1 1 0 Putative NAD(P)-binding Thi4 PF01946.12 KLO20051.1 - 0.023 13.8 0.0 0.041 12.9 0.0 1.3 1 0 0 1 1 1 0 Thi4 family TrkA_N PF02254.13 KLO20051.1 - 0.033 14.1 0.1 0.088 12.8 0.0 1.7 2 0 0 2 2 2 0 TrkA-N domain Saccharop_dh PF03435.13 KLO20051.1 - 0.034 13.1 0.2 0.067 12.1 0.0 1.5 2 0 0 2 2 2 0 Saccharopine dehydrogenase Pyr_redox_2 PF07992.9 KLO20051.1 - 0.096 12.5 0.0 0.15 11.8 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase RRM_1 PF00076.17 KLO20052.1 - 2.4e-25 87.9 0.0 3.3e-13 49.0 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KLO20052.1 - 7.6e-18 64.1 0.0 1.5e-07 31.1 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KLO20052.1 - 3.3e-17 62.2 0.0 4.9e-09 36.0 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 KLO20052.1 - 0.0083 15.8 0.0 0.094 12.4 0.0 2.2 2 0 0 2 2 2 1 Limkain b1 LysM PF01476.15 KLO20053.1 - 2.5e-15 56.0 0.0 3.9e-15 55.4 0.0 1.3 1 0 0 1 1 1 1 LysM domain MARVEL PF01284.18 KLO20054.1 - 4.6e-06 26.5 17.4 5.7e-06 26.2 12.0 1.2 1 0 0 1 1 1 1 Membrane-associating domain Defensin_big PF14862.1 KLO20054.1 - 0.46 10.5 3.2 2.2 8.3 0.3 2.4 2 0 0 2 2 2 0 Big defensin FtsX PF02687.16 KLO20054.1 - 0.79 9.4 12.0 0.14 11.9 0.5 2.3 2 0 0 2 2 2 0 FtsX-like permease family NfeD PF01957.13 KLO20054.1 - 2.9 8.0 12.9 5.3 7.1 3.2 2.1 1 1 1 2 2 2 0 NfeD-like C-terminal, partner-binding Nop14 PF04147.7 KLO20055.1 - 0.06 11.2 0.4 0.091 10.6 0.3 1.2 1 0 0 1 1 1 0 Nop14-like family TatD_DNase PF01026.16 KLO20056.1 - 8.8e-25 87.3 0.0 1.2e-24 86.9 0.0 1.1 1 0 0 1 1 1 1 TatD related DNase Met_10 PF02475.11 KLO20057.1 - 7e-63 211.8 0.0 1.1e-62 211.2 0.0 1.3 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_26 PF13659.1 KLO20057.1 - 0.00018 21.5 0.0 0.0016 18.4 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 KLO20057.1 - 0.00032 21.2 0.0 0.00094 19.7 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KLO20057.1 - 0.0023 17.3 0.0 0.0041 16.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain tRNA_U5-meth_tr PF05958.6 KLO20057.1 - 0.0084 14.8 0.0 0.013 14.2 0.0 1.2 1 0 0 1 1 1 1 tRNA (Uracil-5-)-methyltransferase MethyltransfD12 PF02086.10 KLO20057.1 - 0.0097 15.3 0.0 0.023 14.1 0.0 1.6 1 0 0 1 1 1 1 D12 class N6 adenine-specific DNA methyltransferase Methyltransf_15 PF09445.5 KLO20057.1 - 0.031 13.8 0.0 0.086 12.3 0.0 1.7 2 0 0 2 2 2 0 RNA cap guanine-N2 methyltransferase TRM PF02005.11 KLO20057.1 - 0.048 12.5 0.0 0.071 12.0 0.0 1.2 1 0 0 1 1 1 0 N2,N2-dimethylguanosine tRNA methyltransferase Mito_carr PF00153.22 KLO20058.1 - 5.6e-74 243.9 1.7 2.4e-26 91.2 0.1 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein EF-hand_1 PF00036.27 KLO20058.1 - 3.2e-17 60.4 6.5 1.5e-05 23.9 0.1 6.3 6 0 0 6 6 6 3 EF hand EF-hand_7 PF13499.1 KLO20058.1 - 3.9e-15 55.7 6.7 3.6e-08 33.4 1.4 4.9 2 2 3 5 5 5 4 EF-hand domain pair EF-hand_6 PF13405.1 KLO20058.1 - 5.1e-15 53.9 6.8 1.9e-05 24.1 0.1 5.8 7 0 0 7 7 7 2 EF-hand domain EF-hand_8 PF13833.1 KLO20058.1 - 7.9e-11 41.4 6.6 0.0009 18.8 0.0 5.2 4 1 1 5 5 5 2 EF-hand domain pair EF-hand_5 PF13202.1 KLO20058.1 - 1.9e-07 30.0 8.5 0.00074 18.7 0.1 4.1 4 0 0 4 4 4 2 EF hand DUF953 PF06110.6 KLO20060.1 - 1.1e-10 40.9 0.0 1.3e-10 40.7 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF953) Amidase PF01425.16 KLO20061.1 - 2e-97 326.8 0.0 2.4e-97 326.6 0.0 1.0 1 0 0 1 1 1 1 Amidase Acetyltransf_7 PF13508.1 KLO20062.1 - 4.9e-09 36.2 0.0 1e-08 35.1 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 KLO20062.1 - 8.8e-09 35.0 0.0 1.7e-08 34.1 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_1 PF00583.19 KLO20062.1 - 7e-07 29.1 0.0 1.2e-06 28.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_9 PF13527.1 KLO20062.1 - 8.8e-07 28.8 0.0 1.7e-06 27.8 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 KLO20062.1 - 2.2e-06 27.8 0.0 3.7e-06 27.0 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_13 PF13880.1 KLO20062.1 - 0.0084 15.8 0.0 0.022 14.5 0.0 1.7 1 0 0 1 1 1 1 ESCO1/2 acetyl-transferase MoaC PF01967.16 KLO20063.1 - 1.3e-40 138.2 1.5 1.3e-34 118.7 0.5 3.0 1 1 1 2 2 2 2 MoaC family Mob_synth_C PF06463.8 KLO20063.1 - 6.1e-36 122.9 0.0 1.2e-35 121.9 0.0 1.6 1 0 0 1 1 1 1 Molybdenum Cofactor Synthesis C Radical_SAM PF04055.16 KLO20063.1 - 1e-22 81.1 0.0 1.6e-22 80.4 0.0 1.3 1 0 0 1 1 1 1 Radical SAM superfamily Fer4_12 PF13353.1 KLO20063.1 - 3.1e-07 30.5 0.0 8.2e-07 29.2 0.0 1.7 2 0 0 2 2 2 1 4Fe-4S single cluster domain Fer4_14 PF13394.1 KLO20063.1 - 4e-05 23.6 0.0 0.0001 22.2 0.0 1.6 1 0 0 1 1 1 1 4Fe-4S single cluster domain NIPSNAP PF07978.8 KLO20066.1 - 6.8e-31 106.2 0.3 1.1e-25 89.5 0.0 2.2 2 0 0 2 2 2 2 NIPSNAP Fork_head PF00250.13 KLO20067.1 - 2.6e-20 72.2 0.0 2.7e-20 72.2 0.0 1.0 1 0 0 1 1 1 1 Fork head domain WD40 PF00400.27 KLO20068.1 - 3.5e-77 251.7 21.5 3.8e-08 32.8 0.1 12.2 12 1 0 12 12 12 10 WD domain, G-beta repeat Utp13 PF08625.6 KLO20068.1 - 1.2e-38 131.8 0.0 2e-38 131.2 0.0 1.3 1 0 0 1 1 1 1 Utp13 specific WD40 associated domain Nucleoporin_N PF08801.6 KLO20068.1 - 0.0011 17.7 8.9 3.4 6.3 0.1 4.8 2 1 1 4 4 4 4 Nup133 N terminal like Peptidase_M24 PF00557.19 KLO20070.1 - 8.4e-47 159.4 0.1 1.1e-46 159.0 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 Abhydrolase_3 PF07859.8 KLO20071.1 - 1.7e-47 161.6 0.0 3e-47 160.9 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF2424 PF10340.4 KLO20071.1 - 3.3e-19 68.7 0.0 4.7e-18 64.9 0.0 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF2424) Abhydrolase_6 PF12697.2 KLO20071.1 - 1.4e-06 28.4 0.2 3.5e-06 27.0 0.1 1.7 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KLO20071.1 - 5.6e-05 22.9 0.0 9.4e-05 22.1 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family COesterase PF00135.23 KLO20071.1 - 0.0011 17.7 0.0 0.12 11.1 0.0 2.1 2 0 0 2 2 2 2 Carboxylesterase family Peptidase_S9 PF00326.16 KLO20071.1 - 0.0076 15.4 0.0 0.023 13.9 0.0 1.8 1 1 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_2 PF02230.11 KLO20071.1 - 0.089 12.2 0.0 0.2 11.0 0.0 1.5 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase Exo_endo_phos PF03372.18 KLO20072.1 - 8.1e-19 68.5 0.0 1.1e-18 68.1 0.0 1.1 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family NTF2 PF02136.15 KLO20073.1 - 1.7e-13 50.9 0.0 4.5e-12 46.3 0.0 2.0 1 1 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain Mtr2 PF10429.4 KLO20073.1 - 8.2e-07 28.9 0.0 9.7e-07 28.6 0.0 1.2 1 0 0 1 1 1 1 Nuclear pore RNA shuttling protein Mtr2 SnoaL_2 PF12680.2 KLO20073.1 - 0.024 15.0 0.0 0.033 14.5 0.0 1.3 1 0 0 1 1 1 0 SnoaL-like domain CSF-1 PF05337.6 KLO20077.1 - 0.092 12.0 0.1 0.13 11.5 0.0 1.2 1 0 0 1 1 1 0 Macrophage colony stimulating factor-1 (CSF-1) DBP10CT PF08147.7 KLO20078.1 - 0.081 12.7 1.4 0.4 10.5 0.2 2.1 1 1 1 2 2 2 0 DBP10CT (NUC160) domain HGTP_anticodon PF03129.15 KLO20084.1 - 0.09 12.7 0.0 0.17 11.8 0.0 1.4 1 0 0 1 1 1 0 Anticodon binding domain DUF3406 PF11886.3 KLO20086.1 - 0.077 11.8 0.0 0.11 11.3 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3406) Histone PF00125.19 KLO20087.1 - 6.4e-14 51.8 0.1 7.7e-14 51.5 0.1 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TAF PF02969.12 KLO20087.1 - 2.5e-05 24.1 0.1 3.5e-05 23.6 0.1 1.4 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CENP-S PF15630.1 KLO20087.1 - 3.4e-05 23.9 0.0 4.4e-05 23.5 0.0 1.3 1 1 0 1 1 1 1 Kinetochore component CENP-S CBFD_NFYB_HMF PF00808.18 KLO20087.1 - 0.0016 18.4 0.1 0.003 17.5 0.0 1.6 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Bromo_TP PF07524.8 KLO20087.1 - 0.033 13.9 0.0 0.048 13.4 0.0 1.3 1 0 0 1 1 1 0 Bromodomain associated TFIID-31kDa PF02291.10 KLO20087.1 - 0.039 13.7 0.0 0.051 13.3 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit CENP-T PF15511.1 KLO20087.1 - 0.07 12.3 0.0 0.07 12.3 0.0 1.1 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T RibD_C PF01872.12 KLO20088.1 - 4e-38 131.0 0.1 4.8e-38 130.7 0.1 1.1 1 0 0 1 1 1 1 RibD C-terminal domain Cellulase-like PF12876.2 KLO20088.1 - 0.05 14.0 0.0 0.26 11.7 0.0 2.0 1 1 1 2 2 2 0 Sugar-binding cellulase-like ZZ PF00569.12 KLO20089.1 - 1.1e-33 114.5 43.7 1.9e-09 36.8 4.1 4.4 4 0 0 4 4 4 4 Zinc finger, ZZ type RhoGEF PF00621.15 KLO20090.1 - 1.3e-11 44.7 0.1 1.8e-10 40.9 0.1 2.1 1 1 0 1 1 1 1 RhoGEF domain PUF PF00806.14 KLO20091.1 - 4.4e-29 98.2 0.4 2.2e-08 33.1 0.0 6.0 6 0 0 6 6 6 4 Pumilio-family RNA binding repeat DUF900 PF05990.7 KLO20091.1 - 0.026 13.8 0.0 0.24 10.6 0.0 2.1 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF900) Glyco_hydro_28 PF00295.12 KLO20092.1 - 4.4e-44 150.7 1.9 4.4e-44 150.7 1.3 1.6 2 0 0 2 2 2 1 Glycosyl hydrolases family 28 CBM_4_9 PF02018.12 KLO20092.1 - 0.011 15.7 0.4 0.32 11.0 0.0 2.4 2 0 0 2 2 2 0 Carbohydrate binding domain NmrA PF05368.8 KLO20093.1 - 1.6e-16 60.2 0.0 2.3e-16 59.7 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 KLO20093.1 - 7.2e-14 52.2 0.0 1.1e-13 51.5 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 KLO20093.1 - 0.0036 16.7 0.0 0.0071 15.8 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 KLO20093.1 - 0.05 12.3 0.0 0.089 11.4 0.0 1.4 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family KR PF08659.5 KLO20093.1 - 0.13 11.8 0.3 20 4.8 0.0 2.7 2 1 0 2 2 2 0 KR domain Chorismate_bind PF00425.13 KLO20094.1 - 6.1e-66 222.3 0.0 9.8e-66 221.6 0.0 1.3 1 0 0 1 1 1 1 chorismate binding enzyme GATase PF00117.23 KLO20094.1 - 5.6e-31 107.4 0.0 8.6e-31 106.8 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Anth_synt_I_N PF04715.8 KLO20094.1 - 2.2e-16 60.1 0.0 6.4e-16 58.6 0.0 1.8 2 0 0 2 2 2 1 Anthranilate synthase component I, N terminal region Peptidase_C26 PF07722.8 KLO20094.1 - 3.6e-06 26.5 0.3 6.4e-06 25.7 0.2 1.4 1 0 0 1 1 1 1 Peptidase C26 Transthyretin PF00576.16 KLO20095.1 - 8.7e-32 109.3 0.0 2.5e-31 107.8 0.0 1.7 1 1 0 1 1 1 1 HIUase/Transthyretin family UQ_con PF00179.21 KLO20096.1 - 1.1e-37 128.5 0.2 1.4e-37 128.1 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UEV PF05743.8 KLO20096.1 - 0.014 15.0 0.0 0.027 14.1 0.0 1.5 1 0 0 1 1 1 0 UEV domain RWD PF05773.17 KLO20096.1 - 0.56 10.1 2.6 0.83 9.5 1.8 1.5 1 1 0 1 1 1 0 RWD domain 2OG-FeII_Oxy PF03171.15 KLO20097.1 - 9.9e-05 22.5 0.0 0.0002 21.6 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.1 KLO20097.1 - 0.00038 20.9 0.0 0.00071 20.0 0.0 1.5 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal AA_permease_2 PF13520.1 KLO20098.1 - 1.8e-54 184.8 42.2 2.4e-54 184.5 29.3 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 KLO20098.1 - 2.6e-20 72.2 33.8 2.6e-20 72.2 23.4 1.6 2 0 0 2 2 2 1 Amino acid permease Nop52 PF05997.7 KLO20099.1 - 2.5e-64 216.6 0.0 3.3e-64 216.3 0.0 1.1 1 0 0 1 1 1 1 Nucleolar protein,Nop52 MMS19_N PF14500.1 KLO20099.1 - 1.8e-05 24.1 0.0 4.8e-05 22.7 0.0 1.6 2 0 0 2 2 2 1 Dos2-interacting transcription regulator of RNA-Pol-II DUF2235 PF09994.4 KLO20100.1 - 1.5e-74 250.8 0.0 2e-74 250.4 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) BAAT_C PF08840.6 KLO20100.1 - 0.018 14.7 0.1 0.23 11.1 0.0 2.1 2 0 0 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_5 PF12695.2 KLO20100.1 - 0.12 12.0 0.0 0.24 11.1 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase family Ribosomal_L28e PF01778.12 KLO20101.1 - 7e-30 103.8 0.2 9e-30 103.4 0.2 1.1 1 0 0 1 1 1 1 Ribosomal L28e protein family Corona_nucleoca PF00937.13 KLO20101.1 - 1.2 8.0 8.0 1.4 7.7 5.6 1.1 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein DAP PF15228.1 KLO20102.1 - 0.0027 18.3 10.7 0.015 16.0 7.4 2.1 1 1 0 1 1 1 1 Death-associated protein MRI PF15325.1 KLO20102.1 - 1.8 9.5 5.8 2 9.3 3.5 1.4 1 1 0 1 1 1 0 Modulator of retrovirus infection O-FucT PF10250.4 KLO20104.1 - 6.4e-08 32.0 0.0 8.7e-08 31.6 0.0 1.1 1 0 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase RhoGEF PF00621.15 KLO20105.1 - 1.3e-38 132.7 0.0 1.7e-38 132.2 0.0 1.2 1 0 0 1 1 1 1 RhoGEF domain FYVE PF01363.16 KLO20105.1 - 5.2e-18 64.6 10.4 9e-18 63.9 7.2 1.4 1 0 0 1 1 1 1 FYVE zinc finger PH PF00169.24 KLO20105.1 - 5.4e-07 29.7 0.0 1.3e-06 28.5 0.0 1.6 1 0 0 1 1 1 1 PH domain GPP34 PF05719.6 KLO20105.1 - 0.0056 16.7 3.1 8.6 6.3 0.0 4.2 3 1 0 4 4 4 1 Golgi phosphoprotein 3 (GPP34) FYVE_2 PF02318.11 KLO20105.1 - 0.42 10.5 5.7 0.81 9.6 3.9 1.4 1 0 0 1 1 1 0 FYVE-type zinc finger zf-DHHC PF01529.15 KLO20105.1 - 2.2 7.6 6.0 4.8 6.5 4.2 1.5 1 0 0 1 1 1 0 DHHC palmitoyltransferase Lgl_C PF08596.5 KLO20106.1 - 1.6e-38 132.2 0.0 4.6e-38 130.7 0.0 1.8 1 1 0 1 1 1 1 Lethal giant larvae(Lgl) like, C-terminal WD40 PF00400.27 KLO20106.1 - 0.014 15.2 0.6 0.3 11.0 0.2 3.3 3 0 0 3 3 3 0 WD domain, G-beta repeat DUF1115 PF06544.7 KLO20107.1 - 1.5e-10 40.8 0.0 2.5e-10 40.1 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1115) Acylphosphatase PF00708.13 KLO20107.1 - 0.08 13.0 0.0 0.17 12.0 0.0 1.5 1 0 0 1 1 1 0 Acylphosphatase DUF2358 PF10184.4 KLO20108.1 - 0.00014 21.7 0.0 0.0002 21.2 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2358) RRM_1 PF00076.17 KLO20109.1 - 3.3e-17 61.8 0.0 4.5e-17 61.4 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KLO20109.1 - 1.3e-15 57.1 0.0 1.9e-15 56.5 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KLO20109.1 - 5.3e-09 35.7 0.0 7.7e-09 35.2 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) O-FucT PF10250.4 KLO20110.1 - 1.7e-06 27.4 0.0 2.5e-06 26.8 0.0 1.3 1 0 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase COX5A PF02284.11 KLO20111.1 - 6.8e-40 135.3 0.0 7.9e-40 135.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Va Nramp PF01566.13 KLO20112.1 - 5.7e-86 288.5 22.3 5.7e-86 288.5 15.4 2.2 2 1 0 2 2 2 1 Natural resistance-associated macrophage protein Utp14 PF04615.8 KLO20113.1 - 2.2e-166 555.1 54.5 2.2e-166 555.1 37.8 2.3 1 1 2 3 3 3 1 Utp14 protein Amidohydro_1 PF01979.15 KLO20114.1 - 1.7e-14 54.2 0.1 1.4e-09 38.0 0.0 2.6 3 0 0 3 3 3 2 Amidohydrolase family Amidohydro_4 PF13147.1 KLO20114.1 - 6.6e-13 49.3 2.6 6.2e-12 46.1 1.8 2.2 1 1 0 1 1 1 1 Amidohydrolase Amidohydro_5 PF13594.1 KLO20114.1 - 1.8e-11 43.6 0.0 5.3e-11 42.1 0.0 1.9 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_3 PF07969.6 KLO20114.1 - 7.4e-07 28.7 0.1 0.0027 16.9 0.0 2.3 2 0 0 2 2 2 2 Amidohydrolase family PD40 PF07676.7 KLO20114.1 - 1.3e-05 24.7 0.1 0.063 12.9 0.0 4.0 4 0 0 4 4 4 2 WD40-like Beta Propeller Repeat Adap_comp_sub PF00928.16 KLO20115.1 - 1e-22 80.5 0.0 1.4e-22 80.0 0.0 1.2 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.15 KLO20115.1 - 1.8e-06 27.6 0.1 3.4e-06 26.8 0.1 1.4 1 0 0 1 1 1 1 Clathrin adaptor complex small chain F-box PF00646.28 KLO20116.1 - 0.00038 20.0 0.1 0.001 18.6 0.0 1.7 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 KLO20116.1 - 0.00078 19.1 0.1 0.0025 17.4 0.1 1.9 1 0 0 1 1 1 1 F-box-like Amidohydro_1 PF01979.15 KLO20117.1 - 1.2e-18 67.8 0.1 3.1e-18 66.5 0.1 1.7 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_5 PF13594.1 KLO20117.1 - 2.9e-10 39.8 0.0 6.5e-10 38.6 0.0 1.6 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_4 PF13147.1 KLO20117.1 - 5.3e-09 36.5 0.7 1.5e-08 35.0 0.5 1.9 1 1 0 1 1 1 1 Amidohydrolase Amidohydro_3 PF07969.6 KLO20117.1 - 1.6e-07 30.8 0.9 0.00063 19.0 0.0 2.2 2 0 0 2 2 2 2 Amidohydrolase family NMO PF03060.10 KLO20117.1 - 0.041 13.0 0.0 0.068 12.3 0.0 1.3 1 0 0 1 1 1 0 Nitronate monooxygenase Hira PF07569.6 KLO20118.1 - 4.1e-45 153.6 0.0 1.1e-44 152.2 0.0 1.7 2 0 0 2 2 2 1 TUP1-like enhancer of split WD40 PF00400.27 KLO20118.1 - 2e-42 141.5 26.1 4.8e-09 35.7 0.5 9.5 10 0 0 10 10 10 6 WD domain, G-beta repeat eIF2A PF08662.6 KLO20118.1 - 0.072 12.7 0.1 0.79 9.3 0.0 2.8 3 1 0 3 3 3 0 Eukaryotic translation initiation factor eIF2A Peptidase_S64 PF08192.6 KLO20122.1 - 0.0051 15.2 5.3 0.0068 14.8 3.7 1.1 1 0 0 1 1 1 1 Peptidase family S64 CENP-Q PF13094.1 KLO20122.1 - 0.13 12.2 13.2 0.022 14.7 5.7 2.1 1 1 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit DSX_dimer PF08828.5 KLO20122.1 - 2.1 7.9 5.3 1 8.9 0.2 3.0 3 1 0 3 3 3 0 Doublesex dimerisation domain FMO-like PF00743.14 KLO20123.1 - 6e-41 140.2 0.0 7.1e-30 103.7 0.0 2.5 1 1 1 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 KLO20123.1 - 5.2e-15 56.0 0.0 9.1e-15 55.2 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 KLO20123.1 - 2e-07 30.9 0.3 5.8e-05 22.9 0.3 3.8 2 1 0 2 2 2 1 FAD-NAD(P)-binding K_oxygenase PF13434.1 KLO20123.1 - 2.5e-07 29.9 0.1 5.1e-05 22.3 0.0 2.8 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 KLO20123.1 - 3.5e-06 27.0 0.0 0.00024 21.0 0.0 2.6 1 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KLO20123.1 - 0.0002 21.2 1.1 0.00053 19.9 0.0 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 KLO20123.1 - 0.023 13.8 0.0 0.39 9.7 0.0 2.2 2 0 0 2 2 2 0 Thi4 family Shikimate_DH PF01488.15 KLO20123.1 - 0.097 12.7 0.2 10 6.1 0.0 2.3 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase NGP1NT PF08153.7 KLO20124.1 - 5.1e-46 155.8 0.0 1.1e-45 154.7 0.0 1.5 1 0 0 1 1 1 1 NGP1NT (NUC091) domain MMR_HSR1 PF01926.18 KLO20124.1 - 2.7e-19 69.2 0.1 1.7e-15 57.0 0.0 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase FeoB_N PF02421.13 KLO20124.1 - 6.7e-05 22.2 0.4 0.00041 19.6 0.0 2.1 2 0 0 2 2 2 1 Ferrous iron transport protein B GTP_EFTU PF00009.22 KLO20124.1 - 0.00011 21.6 0.0 0.029 13.8 0.0 3.0 2 1 0 3 3 3 1 Elongation factor Tu GTP binding domain DUF258 PF03193.11 KLO20124.1 - 0.00086 18.5 0.0 0.0017 17.5 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Dynamin_N PF00350.18 KLO20124.1 - 0.018 14.8 0.9 4.7 6.9 0.1 3.6 2 1 1 3 3 3 0 Dynamin family Arf PF00025.16 KLO20124.1 - 0.033 13.4 0.0 0.38 9.9 0.0 2.3 2 0 0 2 2 2 0 ADP-ribosylation factor family DUF4611 PF15387.1 KLO20124.1 - 1.6 8.9 19.0 3.4 7.8 3.1 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) IBN_N PF03810.14 KLO20126.1 - 1.4e-09 37.7 0.0 5.9e-06 26.1 0.0 3.6 2 1 1 3 3 3 2 Importin-beta N-terminal domain HEAT_2 PF13646.1 KLO20126.1 - 0.00017 21.8 2.1 0.029 14.6 0.0 5.0 2 2 4 6 6 6 2 HEAT repeats Xpo1 PF08389.7 KLO20126.1 - 0.0059 16.5 1.5 0.19 11.6 0.1 4.2 5 2 0 5 5 5 1 Exportin 1-like protein Adaptin_N PF01602.15 KLO20126.1 - 0.0074 14.6 0.7 0.043 12.1 0.1 2.4 2 1 0 2 2 2 1 Adaptin N terminal region ParcG PF10274.4 KLO20126.1 - 0.011 15.5 1.3 6.1 6.6 0.0 2.9 3 0 0 3 3 3 0 Parkin co-regulated protein CAS_CSE1 PF03378.10 KLO20126.1 - 0.016 13.5 2.7 0.026 12.8 0.0 2.6 4 0 0 4 4 4 0 CAS/CSE protein, C-terminus Cse1 PF08506.5 KLO20126.1 - 0.022 13.3 0.0 0.057 11.9 0.0 1.9 1 1 0 1 1 1 0 Cse1 HEAT PF02985.17 KLO20126.1 - 0.052 13.6 0.1 0.052 13.6 0.0 5.5 7 0 0 7 7 7 0 HEAT repeat RIX1 PF08167.7 KLO20126.1 - 0.059 13.0 3.9 0.35 10.5 0.2 3.4 3 1 0 3 3 3 0 rRNA processing/ribosome biogenesis F-box-like PF12937.2 KLO20127.1 - 0.00023 20.8 0.8 0.00052 19.6 0.6 1.7 1 0 0 1 1 1 1 F-box-like Dor1 PF04124.7 KLO20129.1 - 6.5e-63 212.2 5.3 8.2e-63 211.8 3.7 1.1 1 0 0 1 1 1 1 Dor1-like family Vps51 PF08700.6 KLO20129.1 - 1.4e-05 24.8 0.0 4.2e-05 23.2 0.0 1.8 1 0 0 1 1 1 1 Vps51/Vps67 COG2 PF06148.6 KLO20129.1 - 0.044 13.6 0.5 0.29 11.0 0.1 2.4 2 1 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Inositol_P PF00459.20 KLO20130.1 - 2.4e-63 214.0 0.0 2.6e-63 213.8 0.0 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family Proteasome PF00227.21 KLO20131.1 - 8e-58 194.8 0.1 1e-57 194.5 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 KLO20131.1 - 2.1e-14 52.5 0.0 3.6e-14 51.7 0.0 1.4 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Ribonuc_L-PSP PF01042.16 KLO20132.1 - 3.2e-39 133.4 0.2 3.6e-39 133.2 0.2 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP UCH PF00443.24 KLO20134.1 - 3.6e-45 154.1 0.1 1.4e-44 152.2 0.0 2.0 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase RPT PF13446.1 KLO20134.1 - 2.3e-24 84.5 0.2 2.8e-18 65.0 0.0 2.6 2 0 0 2 2 2 2 A repeated domain in UCH-protein UCH_1 PF13423.1 KLO20134.1 - 5.9e-14 52.2 2.7 8.1e-09 35.3 0.4 2.8 2 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase PUB PF09409.5 KLO20134.1 - 0.046 13.4 0.0 0.15 11.8 0.0 1.9 1 0 0 1 1 1 0 PUB domain APG6 PF04111.7 KLO20134.1 - 0.27 10.2 4.1 0.53 9.2 2.9 1.5 1 0 0 1 1 1 0 Autophagy protein Apg6 p450 PF00067.17 KLO20136.1 - 7.7e-76 255.4 0.0 1.1e-75 255.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 KLO20137.1 - 1.8e-73 247.6 0.0 2.7e-73 247.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Glyco_transf_15 PF01793.11 KLO20138.1 - 7.6e-132 439.2 12.6 8.6e-132 439.0 8.7 1.0 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase zf-CCHC PF00098.18 KLO20141.1 - 4.6e-05 23.1 1.3 9.9e-05 22.0 0.4 2.0 2 0 0 2 2 2 1 Zinc knuckle YL1 PF05764.8 KLO20141.1 - 0.23 11.0 6.0 0.39 10.2 4.1 1.4 1 0 0 1 1 1 0 YL1 nuclear protein PPP4R2 PF09184.6 KLO20141.1 - 0.98 8.9 6.0 1.7 8.1 4.1 1.4 1 0 0 1 1 1 0 PPP4R2 CDC45 PF02724.9 KLO20141.1 - 2.4 6.1 7.5 3.2 5.6 5.2 1.2 1 0 0 1 1 1 0 CDC45-like protein Phage_int_SAM_3 PF14659.1 KLO20142.1 - 0.017 15.3 0.0 0.043 14.0 0.0 1.6 1 0 0 1 1 1 0 Phage integrase, N-terminal SAM-like domain Phage_int_SAM_4 PF13495.1 KLO20142.1 - 0.098 12.9 0.0 0.24 11.7 0.0 1.6 1 0 0 1 1 1 0 Phage integrase, N-terminal SAM-like domain Phage_integrase PF00589.17 KLO20142.1 - 0.1 12.2 0.0 0.18 11.4 0.0 1.4 1 1 0 1 1 1 0 Phage integrase family F-box PF00646.28 KLO20143.1 - 0.019 14.6 0.2 0.043 13.4 0.1 1.7 1 0 0 1 1 1 0 F-box domain Ribosomal_S15 PF00312.17 KLO20144.1 - 3.8e-16 58.5 0.2 7.7e-16 57.6 0.1 1.5 1 0 0 1 1 1 1 Ribosomal protein S15 UCH PF00443.24 KLO20145.1 - 4.7e-65 219.3 0.0 6e-65 219.0 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 KLO20145.1 - 1.1e-35 123.4 1.4 7.8e-27 94.4 0.1 2.2 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase Peptidase_C98 PF15499.1 KLO20145.1 - 0.77 8.9 3.8 1.7 7.8 2.0 2.0 3 1 0 3 3 3 0 Ubiquitin-specific peptidase-like, SUMO isopeptidase MOSC PF03473.12 KLO20146.1 - 8.2e-18 64.1 0.0 1.5e-17 63.2 0.0 1.4 1 0 0 1 1 1 1 MOSC domain MOSC_N PF03476.11 KLO20146.1 - 1.1e-17 63.8 0.0 1.7e-17 63.1 0.0 1.3 1 0 0 1 1 1 1 MOSC N-terminal beta barrel domain Rotamase PF00639.16 KLO20147.1 - 8.3e-23 80.9 0.0 1.1e-22 80.5 0.0 1.2 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_3 PF13616.1 KLO20147.1 - 1.5e-19 70.4 0.0 2.1e-19 69.9 0.0 1.1 1 0 0 1 1 1 1 PPIC-type PPIASE domain WW PF00397.21 KLO20147.1 - 1.5e-09 37.5 0.2 1.5e-09 37.5 0.1 1.6 2 0 0 2 2 2 1 WW domain Rotamase_2 PF13145.1 KLO20147.1 - 8.1e-05 23.2 0.0 0.00012 22.7 0.0 1.3 1 0 0 1 1 1 1 PPIC-type PPIASE domain Sel1 PF08238.7 KLO20148.1 - 1.4e-42 143.1 30.7 3.1e-08 34.0 0.2 7.7 8 0 0 8 8 8 7 Sel1 repeat CPSase_L_D2 PF02786.12 KLO20149.1 - 1.2e-77 259.9 0.0 2.1e-77 259.1 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_chain PF00289.17 KLO20149.1 - 4.3e-44 149.1 0.1 3.5e-43 146.1 0.0 2.6 2 0 0 2 2 2 1 Carbamoyl-phosphate synthase L chain, N-terminal domain Biotin_carb_C PF02785.14 KLO20149.1 - 1.2e-33 115.3 0.0 2.3e-33 114.3 0.0 1.5 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain ATPgrasp_Ter PF15632.1 KLO20149.1 - 3.2e-16 59.0 0.0 1.3e-15 56.9 0.0 1.8 1 1 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp_4 PF13535.1 KLO20149.1 - 4.6e-16 59.0 0.1 4.2e-15 55.9 0.0 2.2 2 0 0 2 2 2 1 ATP-grasp domain Biotin_lipoyl PF00364.17 KLO20149.1 - 3.6e-15 55.3 2.0 9.6e-15 53.9 1.4 1.8 1 0 0 1 1 1 1 Biotin-requiring enzyme Dala_Dala_lig_C PF07478.8 KLO20149.1 - 2.3e-13 50.0 0.0 4.7e-13 48.9 0.0 1.5 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.17 KLO20149.1 - 1.9e-10 40.3 0.0 1.1e-09 37.8 0.0 2.2 2 0 0 2 2 2 1 ATP-grasp domain ATP-grasp_3 PF02655.9 KLO20149.1 - 1.7e-05 24.7 0.0 3.2e-05 23.8 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain RimK PF08443.6 KLO20149.1 - 5.2e-05 22.8 0.0 0.00015 21.3 0.0 1.7 1 1 0 1 1 1 1 RimK-like ATP-grasp domain Biotin_lipoyl_2 PF13533.1 KLO20149.1 - 5.9e-05 22.6 0.2 0.028 14.0 0.1 2.5 1 1 1 2 2 2 2 Biotin-lipoyl like HlyD_3 PF13437.1 KLO20149.1 - 0.00058 20.1 0.3 1.3 9.4 0.0 2.5 2 0 0 2 2 2 2 HlyD family secretion protein GARS_A PF01071.14 KLO20149.1 - 0.0028 17.2 0.0 0.0057 16.2 0.0 1.5 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain HlyD PF00529.15 KLO20149.1 - 0.018 14.3 0.8 0.11 11.8 0.0 2.1 1 1 1 2 2 2 0 HlyD family secretion protein Epimerase PF01370.16 KLO20150.1 - 7.5e-38 130.2 0.0 9.7e-38 129.9 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Epimerase_Csub PF13950.1 KLO20150.1 - 3e-24 84.7 0.0 5.5e-24 83.8 0.0 1.4 1 0 0 1 1 1 1 UDP-glucose 4-epimerase C-term subunit 3Beta_HSD PF01073.14 KLO20150.1 - 2e-10 39.8 0.0 5.7e-10 38.3 0.0 1.7 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 KLO20150.1 - 2.7e-09 36.3 0.0 5.4e-09 35.3 0.0 1.5 1 0 0 1 1 1 1 Male sterility protein RmlD_sub_bind PF04321.12 KLO20150.1 - 2e-08 33.4 0.0 1.4e-07 30.7 0.0 1.9 1 1 0 1 1 1 1 RmlD substrate binding domain adh_short PF00106.20 KLO20150.1 - 3.4e-08 33.6 0.0 6.5e-08 32.6 0.0 1.5 1 0 0 1 1 1 1 short chain dehydrogenase Polysacc_synt_2 PF02719.10 KLO20150.1 - 3.4e-08 32.7 0.0 3.8e-07 29.3 0.0 2.3 3 0 0 3 3 3 1 Polysaccharide biosynthesis protein KR PF08659.5 KLO20150.1 - 6e-07 29.2 0.0 1.4e-06 28.0 0.0 1.7 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 KLO20150.1 - 0.00019 21.4 0.0 0.0012 18.8 0.0 2.0 1 1 0 1 1 1 1 NADH(P)-binding 4HBT PF03061.17 KLO20151.1 - 9.4e-13 48.0 0.5 5.7e-05 23.1 0.2 2.4 2 0 0 2 2 2 2 Thioesterase superfamily efThoc1 PF11957.3 KLO20154.1 - 1.6e-102 343.5 4.4 7.5e-97 324.8 1.7 2.1 2 0 0 2 2 2 2 THO complex subunit 1 transcription elongation factor Nucleo_P87 PF07267.6 KLO20154.1 - 0.039 12.6 0.2 0.068 11.8 0.1 1.3 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 PAT1 PF09770.4 KLO20154.1 - 5.6 5.0 9.0 7.9 4.5 6.2 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Pkinase PF00069.20 KLO20155.1 - 6.2e-67 225.4 0.0 7.9e-67 225.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KLO20155.1 - 1.1e-30 106.6 0.0 1.5e-30 106.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 KLO20155.1 - 0.00011 21.3 0.1 0.00032 19.8 0.0 1.7 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KLO20155.1 - 0.00011 21.9 0.5 0.00055 19.7 0.0 2.0 1 1 0 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.1 KLO20155.1 - 0.0077 15.2 0.0 0.013 14.4 0.0 1.5 1 1 0 1 1 1 1 Kinase-like Choline_kinase PF01633.15 KLO20155.1 - 0.041 13.4 0.1 0.084 12.4 0.1 1.6 1 0 0 1 1 1 0 Choline/ethanolamine kinase Seadorna_VP7 PF07387.6 KLO20155.1 - 0.055 12.2 0.0 0.082 11.7 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 DUF1361 PF07099.6 KLO20155.1 - 0.13 12.1 0.1 0.2 11.4 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1361) DUF1469 PF07332.6 KLO20156.1 - 0.11 12.2 1.6 0.2 11.3 1.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1469) Cortexin PF11057.3 KLO20156.1 - 0.13 11.8 0.9 0.27 10.8 0.6 1.6 1 0 0 1 1 1 0 Cortexin of kidney DUF4282 PF14110.1 KLO20156.1 - 0.44 10.7 3.1 0.68 10.1 2.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4282) Peroxidase_2 PF01328.12 KLO20157.1 - 5.2e-24 84.4 0.2 8.4e-15 54.2 0.1 3.0 3 0 0 3 3 3 3 Peroxidase, family 2 Vps51 PF08700.6 KLO20158.1 - 3.6e-17 61.9 0.9 1.1e-16 60.4 0.6 1.9 1 0 0 1 1 1 1 Vps51/Vps67 COG2 PF06148.6 KLO20158.1 - 1.6e-05 24.7 0.8 4e-05 23.4 0.6 1.7 1 0 0 1 1 1 1 COG (conserved oligomeric Golgi) complex component, COG2 L27_2 PF09045.5 KLO20158.1 - 0.022 14.2 0.3 6.3 6.4 0.0 2.7 2 0 0 2 2 2 0 L27_2 Lactamase_B PF00753.22 KLO20159.1 - 3.1e-20 72.6 1.3 3e-10 40.0 0.0 2.3 2 1 0 2 2 2 2 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 KLO20159.1 - 3.9e-08 33.0 0.3 5.2e-08 32.6 0.2 1.2 1 0 0 1 1 1 1 Beta-lactamase superfamily domain DNA_methylase PF00145.12 KLO20160.1 - 2.4e-35 122.2 0.0 1.5e-33 116.3 0.0 2.6 1 1 0 1 1 1 1 C-5 cytosine-specific DNA methylase BAH PF01426.13 KLO20160.1 - 9.3e-21 73.7 0.0 5.7e-16 58.3 0.0 2.5 2 0 0 2 2 2 2 BAH domain Methyltransf_26 PF13659.1 KLO20160.1 - 0.0008 19.4 0.0 0.0015 18.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Met_10 PF02475.11 KLO20160.1 - 0.01 15.4 0.0 0.023 14.3 0.0 1.5 1 0 0 1 1 1 0 Met-10+ like-protein E1-E2_ATPase PF00122.15 KLO20160.1 - 0.17 10.8 0.0 0.27 10.2 0.0 1.2 1 0 0 1 1 1 0 E1-E2 ATPase Dus PF01207.12 KLO20161.1 - 3e-52 177.4 0.0 5.5e-52 176.5 0.0 1.3 1 1 0 1 1 1 1 Dihydrouridine synthase (Dus) ADH_zinc_N PF00107.21 KLO20162.1 - 3.4e-12 46.0 0.7 7.5e-12 44.9 0.5 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 KLO20162.1 - 5.5e-08 32.5 0.0 9.7e-08 31.7 0.0 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Pkinase PF00069.20 KLO20163.1 - 4e-72 242.5 0.0 4.8e-72 242.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KLO20163.1 - 2.3e-31 108.7 0.0 3.1e-31 108.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 KLO20163.1 - 0.0003 19.9 0.0 0.0008 18.5 0.0 1.6 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 KLO20163.1 - 0.00052 19.8 0.0 0.00088 19.0 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.1 KLO20163.1 - 0.0013 17.7 0.0 0.025 13.5 0.0 2.1 1 1 1 2 2 2 1 Kinase-like RIO1 PF01163.17 KLO20163.1 - 0.03 13.6 0.0 0.051 12.9 0.0 1.3 1 0 0 1 1 1 0 RIO1 family Abhydrolase_3 PF07859.8 KLO20164.1 - 1.6e-36 125.8 0.0 2e-36 125.5 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 KLO20164.1 - 1.1e-07 31.2 0.0 1.9e-07 30.5 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_6 PF12697.2 KLO20164.1 - 3.4e-07 30.3 0.1 1.2e-06 28.5 0.1 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KLO20164.1 - 4.3e-07 29.7 0.0 5.8e-07 29.3 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family DLH PF01738.13 KLO20164.1 - 2.5e-06 26.9 0.0 1.3e-05 24.6 0.0 1.9 1 1 0 1 1 1 1 Dienelactone hydrolase family DUF2974 PF11187.3 KLO20164.1 - 0.0058 16.0 0.0 0.008 15.5 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2974) Abhydrolase_2 PF02230.11 KLO20164.1 - 0.027 13.9 0.1 0.052 12.9 0.0 1.5 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Lipase_3 PF01764.20 KLO20164.1 - 0.03 13.9 0.0 0.041 13.4 0.0 1.2 1 0 0 1 1 1 0 Lipase (class 3) Amidohydro_4 PF13147.1 KLO20165.1 - 3.2e-19 70.0 3.4 1.2e-16 61.5 0.5 3.7 2 2 0 2 2 2 2 Amidohydrolase Amidohydro_5 PF13594.1 KLO20165.1 - 9.4e-13 47.7 0.0 9.8e-08 31.7 0.0 2.8 2 0 0 2 2 2 2 Amidohydrolase Amidohydro_1 PF01979.15 KLO20165.1 - 8.9e-09 35.4 0.1 0.00013 21.7 0.0 3.4 3 1 0 3 3 3 3 Amidohydrolase family Amidohydro_3 PF07969.6 KLO20165.1 - 0.0027 17.0 0.0 0.29 10.2 0.0 2.4 2 0 0 2 2 2 2 Amidohydrolase family DUF2235 PF09994.4 KLO20166.1 - 3e-78 262.9 0.0 4.2e-78 262.5 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) Abhydrolase_5 PF12695.2 KLO20166.1 - 0.021 14.5 0.0 0.063 13.0 0.0 1.9 2 0 0 2 2 2 0 Alpha/beta hydrolase family FAM101 PF15068.1 KLO20166.1 - 0.072 12.5 0.0 0.12 11.7 0.0 1.3 1 0 0 1 1 1 0 FAM101 family E1_DerP2_DerF2 PF02221.10 KLO20167.1 - 7.1e-27 94.2 0.8 8.1e-27 94.0 0.5 1.0 1 0 0 1 1 1 1 ML domain TRP_N PF14558.1 KLO20167.1 - 4.5e-06 26.7 0.1 7.4e-06 26.0 0.1 1.5 1 1 0 1 1 1 1 ML-like domain Enolase_C PF00113.17 KLO20167.1 - 0.055 12.4 0.0 0.062 12.2 0.0 1.2 1 0 0 1 1 1 0 Enolase, C-terminal TIM barrel domain Tetraspannin PF00335.15 KLO20168.1 - 0.023 13.9 10.5 0.011 14.9 5.7 1.6 1 1 0 1 1 1 0 Tetraspanin family Glyco_hydro_88 PF07470.8 KLO20169.1 - 2.4e-28 99.1 0.1 2.9e-28 98.8 0.0 1.1 1 0 0 1 1 1 1 Glycosyl Hydrolase Family 88 Cellulase PF00150.13 KLO20170.1 - 9.7e-23 80.7 0.4 1.2e-22 80.4 0.3 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Cellulase-like PF12876.2 KLO20170.1 - 0.00021 21.6 0.0 0.00044 20.6 0.0 1.6 1 1 0 1 1 1 1 Sugar-binding cellulase-like Glyco_hydro_10 PF00331.15 KLO20170.1 - 0.016 14.2 0.0 0.028 13.4 0.0 1.3 1 0 0 1 1 1 0 Glycosyl hydrolase family 10 Glyco_hydro_42 PF02449.10 KLO20170.1 - 0.038 13.1 0.0 0.095 11.8 0.0 1.6 1 0 0 1 1 1 0 Beta-galactosidase EF-hand_1 PF00036.27 KLO20171.1 - 2.3e-19 67.1 13.1 1.1e-07 30.6 0.2 3.6 3 0 0 3 3 3 3 EF hand EF-hand_7 PF13499.1 KLO20171.1 - 5.3e-19 68.1 10.4 2.4e-11 43.5 2.2 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 KLO20171.1 - 2.8e-15 54.7 13.4 8.9e-07 28.2 0.3 4.6 3 1 1 4 4 4 3 EF-hand domain EF-hand_8 PF13833.1 KLO20171.1 - 3.2e-14 52.2 13.7 2.7e-08 33.3 1.1 3.3 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_4 PF12763.2 KLO20171.1 - 1.6e-05 24.5 4.6 0.0044 16.7 0.1 2.8 1 1 2 3 3 3 2 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.1 KLO20171.1 - 0.00011 22.0 0.4 0.084 12.8 0.1 2.2 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.1 KLO20171.1 - 0.00067 18.8 13.0 0.0098 15.2 0.4 3.7 4 1 1 5 5 5 2 EF hand SPARC_Ca_bdg PF10591.4 KLO20171.1 - 0.014 15.4 2.6 0.34 10.9 0.4 2.5 2 1 1 3 3 3 0 Secreted protein acidic and rich in cysteine Ca binding region DUF4373 PF14297.1 KLO20171.1 - 0.029 14.6 0.3 3 8.1 0.0 2.5 2 1 1 3 3 3 0 Domain of unknown function (DUF4373) DUF4250 PF14056.1 KLO20171.1 - 1.3 8.7 3.9 8.5 6.1 0.1 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4250) TauD PF02668.11 KLO20172.1 - 3.5e-50 171.0 0.1 4.7e-50 170.6 0.0 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family CorA PF01544.13 KLO20173.1 - 1.5e-31 109.5 8.1 3.7e-30 104.9 5.1 2.3 2 1 0 2 2 2 2 CorA-like Mg2+ transporter protein V_ATPase_I PF01496.14 KLO20173.1 - 0.14 9.9 6.5 0.21 9.4 4.5 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family CorA PF01544.13 KLO20174.1 - 1.1e-31 110.0 6.7 1.5e-29 102.9 3.8 2.4 2 1 0 2 2 2 2 CorA-like Mg2+ transporter protein V_ATPase_I PF01496.14 KLO20174.1 - 0.03 12.2 5.0 0.045 11.6 3.5 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family CorA PF01544.13 KLO20175.1 - 1.4e-33 116.1 0.3 7.6e-30 103.9 0.1 2.3 2 0 0 2 2 2 2 CorA-like Mg2+ transporter protein V_ATPase_I PF01496.14 KLO20175.1 - 0.058 11.2 2.0 0.099 10.4 1.4 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family p450 PF00067.17 KLO20176.1 - 7.3e-70 235.7 0.0 9e-70 235.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 KLO20177.1 - 2.4e-64 217.6 0.0 5.8e-57 193.2 0.0 2.1 1 1 1 2 2 2 2 Cytochrome P450 DUF2156 PF09924.4 KLO20178.1 - 4.6e-23 81.4 0.0 5.3e-23 81.2 0.0 1.0 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2156) ICEA PF05315.6 KLO20178.1 - 0.032 13.5 0.5 0.046 13.0 0.4 1.2 1 0 0 1 1 1 0 ICEA Protein UPF0147 PF03685.8 KLO20178.1 - 0.1 12.4 0.0 0.29 11.0 0.0 1.8 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0147) Cellulase PF00150.13 KLO20179.1 - 8e-14 51.4 0.0 1.6e-13 50.4 0.0 1.6 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) DUF1515 PF07439.6 KLO20180.1 - 0.37 10.6 2.4 0.72 9.6 1.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1515) Glyco_transf_17 PF04724.8 KLO20181.1 - 7.9e-63 212.6 0.0 1e-62 212.2 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 17 Lum_binding PF00677.12 KLO20182.1 - 2.3e-37 126.7 0.1 9.3e-20 70.3 0.0 2.2 2 0 0 2 2 2 2 Lumazine binding domain Polyketide_cyc2 PF10604.4 KLO20182.1 - 0.01 15.9 1.9 0.12 12.5 0.1 2.2 1 1 1 2 2 2 0 Polyketide cyclase / dehydrase and lipid transport DUF4611 PF15387.1 KLO20183.1 - 5.8 7.1 12.0 36 4.5 0.5 3.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4611) CRAL_TRIO PF00650.15 KLO20184.1 - 1e-36 125.8 0.0 1.4e-36 125.3 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.1 KLO20184.1 - 8.3e-06 25.7 0.0 1.4e-05 25.0 0.0 1.3 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain CRAL_TRIO_N PF03765.10 KLO20184.1 - 0.00032 20.7 1.0 0.00068 19.7 0.7 1.6 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain polyprenyl_synt PF00348.12 KLO20185.1 - 1.9e-44 151.5 0.0 6.7e-41 139.8 0.0 2.5 2 1 0 2 2 2 2 Polyprenyl synthetase SQS_PSY PF00494.14 KLO20185.1 - 0.045 13.0 0.8 0.38 9.9 0.6 2.3 1 1 0 1 1 1 0 Squalene/phytoene synthase polyprenyl_synt PF00348.12 KLO20186.1 - 1.3e-42 145.5 0.0 3.9e-39 134.0 0.0 2.4 2 1 0 2 2 2 2 Polyprenyl synthetase RasGEF PF00617.14 KLO20188.1 - 8.5e-40 136.4 0.0 1.3e-39 135.8 0.0 1.3 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.15 KLO20188.1 - 5.2e-18 65.0 0.0 1.2e-17 63.8 0.0 1.6 1 0 0 1 1 1 1 RasGEF N-terminal motif SH3_1 PF00018.23 KLO20188.1 - 2.6e-13 49.1 0.2 6.5e-13 47.8 0.1 1.7 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 KLO20188.1 - 1.9e-10 40.0 0.0 1.7e-09 36.9 0.0 2.4 2 0 0 2 2 2 1 Variant SH3 domain SH3_9 PF14604.1 KLO20188.1 - 8.8e-09 34.8 0.1 1.7e-08 33.9 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain DUF605 PF04652.11 KLO20188.1 - 2.2 7.5 7.4 4.4 6.5 5.1 1.5 1 0 0 1 1 1 0 Vta1 like Ras PF00071.17 KLO20189.1 - 1.5e-55 187.0 0.3 1.7e-55 186.8 0.2 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KLO20189.1 - 3.1e-19 69.6 0.0 4.4e-19 69.1 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KLO20189.1 - 1.5e-14 53.6 0.0 1.7e-14 53.4 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 KLO20189.1 - 7.3e-07 28.5 0.0 9e-07 28.2 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 KLO20189.1 - 9.6e-07 28.4 0.0 1.8e-06 27.5 0.0 1.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 KLO20189.1 - 0.00015 21.7 0.0 0.00019 21.3 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase G-alpha PF00503.15 KLO20189.1 - 0.02 13.6 0.6 1.2 7.7 0.2 2.2 1 1 1 2 2 2 0 G-protein alpha subunit AAA_14 PF13173.1 KLO20189.1 - 0.036 13.9 0.0 0.059 13.2 0.0 1.4 1 1 0 1 1 1 0 AAA domain DUF258 PF03193.11 KLO20189.1 - 0.037 13.2 0.1 0.081 12.1 0.1 1.6 1 1 0 1 1 1 0 Protein of unknown function, DUF258 AAA_22 PF13401.1 KLO20189.1 - 0.04 14.0 0.0 0.32 11.1 0.0 2.3 1 1 0 1 1 1 0 AAA domain NTPase_1 PF03266.10 KLO20189.1 - 0.062 13.0 0.0 0.11 12.2 0.0 1.4 1 1 0 1 1 1 0 NTPase AAA_16 PF13191.1 KLO20189.1 - 0.066 13.1 0.1 0.092 12.7 0.1 1.6 1 1 0 1 1 1 0 AAA ATPase domain Septin PF00735.13 KLO20189.1 - 0.13 11.2 0.1 0.19 10.6 0.0 1.2 1 0 0 1 1 1 0 Septin RRM_1 PF00076.17 KLO20190.1 - 4.4e-12 45.4 0.1 2.1e-10 40.0 0.0 2.3 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KLO20190.1 - 3.8e-09 36.2 0.0 0.00047 19.9 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KLO20190.1 - 4.7e-08 32.8 0.1 2.2e-06 27.5 0.0 2.3 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Bromodomain PF00439.20 KLO20191.1 - 9e-61 201.7 0.2 6.4e-21 74.0 0.0 3.6 3 0 0 3 3 3 3 Bromodomain Peptidase_M1 PF01433.15 KLO20191.1 - 6e-11 42.0 0.0 1.6e-05 24.1 0.0 3.2 2 1 1 3 3 3 2 Peptidase family M1 SRP-alpha_N PF04086.8 KLO20191.1 - 0.015 14.7 3.2 0.043 13.1 2.2 1.8 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Methyltransf_23 PF13489.1 KLO20192.1 - 2.1e-09 37.2 0.0 3.5e-09 36.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 KLO20192.1 - 1.4e-05 25.5 0.0 2.7e-05 24.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 KLO20192.1 - 1.8e-05 23.9 0.0 2.8e-05 23.2 0.0 1.2 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_12 PF08242.7 KLO20192.1 - 1.9e-05 25.0 0.0 3.7e-05 24.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.13 KLO20192.1 - 4.3e-05 22.8 0.0 6.3e-05 22.2 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_31 PF13847.1 KLO20192.1 - 5e-05 22.9 0.0 0.00034 20.2 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KLO20192.1 - 0.00036 21.0 0.2 0.0019 18.7 0.1 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 KLO20192.1 - 0.00064 20.0 0.1 0.0016 18.7 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.14 KLO20192.1 - 0.0033 17.4 0.0 0.005 16.8 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase PrmA PF06325.8 KLO20192.1 - 0.012 14.7 0.0 0.017 14.2 0.0 1.1 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.9 KLO20192.1 - 0.017 14.5 0.0 0.032 13.5 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain Ubie_methyltran PF01209.13 KLO20192.1 - 0.032 13.3 0.0 0.067 12.2 0.0 1.4 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_26 PF13659.1 KLO20192.1 - 0.086 12.8 0.1 0.24 11.4 0.1 1.7 1 1 0 1 1 1 0 Methyltransferase domain Ist1 PF03398.9 KLO20193.1 - 8.2e-54 181.4 0.0 1e-53 181.1 0.0 1.1 1 0 0 1 1 1 1 Regulator of Vps4 activity in the MVB pathway GRAM PF02893.15 KLO20194.1 - 2.7e-16 58.8 0.0 8.5e-16 57.2 0.0 1.9 1 0 0 1 1 1 1 GRAM domain Thioredoxin PF00085.15 KLO20195.1 - 8.3e-29 99.3 0.0 9.5e-29 99.1 0.0 1.0 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.1 KLO20195.1 - 1.4e-07 31.6 0.1 1.8e-06 28.1 0.1 2.0 1 1 0 1 1 1 1 Thioredoxin-like domain AhpC-TSA PF00578.16 KLO20195.1 - 4.3e-05 23.2 0.0 4.9e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_8 PF13905.1 KLO20195.1 - 5.5e-05 23.2 0.0 0.00025 21.1 0.0 2.0 1 1 1 2 2 2 1 Thioredoxin-like Thioredoxin_9 PF14595.1 KLO20195.1 - 8.6e-05 22.1 0.0 0.0001 21.8 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Redoxin PF08534.5 KLO20195.1 - 0.0006 19.3 0.1 0.004 16.7 0.0 1.8 1 1 1 2 2 2 1 Redoxin Thioredoxin_7 PF13899.1 KLO20195.1 - 0.021 14.8 0.0 0.027 14.4 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin-like Glutaredoxin PF00462.19 KLO20195.1 - 0.025 14.5 0.0 0.059 13.3 0.0 1.6 1 1 0 1 1 1 0 Glutaredoxin Pyridox_oxase_2 PF12766.2 KLO20196.1 - 4.7e-26 91.0 0.0 7.4e-26 90.3 0.0 1.3 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Pyridox_oxidase PF01243.15 KLO20196.1 - 8.8e-06 25.6 0.0 1.6e-05 24.7 0.0 1.4 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Pkinase PF00069.20 KLO20198.1 - 4.9e-61 206.1 0.0 1.6e-60 204.4 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KLO20198.1 - 4.2e-27 94.8 0.0 2.8e-15 56.1 0.0 2.2 1 1 1 2 2 2 2 Protein tyrosine kinase Pkinase_C PF00433.19 KLO20198.1 - 7.8e-06 26.3 3.7 7.8e-06 26.3 2.5 2.8 2 0 0 2 2 2 1 Protein kinase C terminal domain Kinase-like PF14531.1 KLO20198.1 - 0.00054 19.0 0.0 0.026 13.4 0.0 2.3 2 0 0 2 2 2 1 Kinase-like PX PF00787.19 KLO20198.1 - 0.0013 18.4 0.1 0.03 14.1 0.0 2.9 3 0 0 3 3 3 1 PX domain Kdo PF06293.9 KLO20198.1 - 0.0034 16.4 0.0 0.008 15.2 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Hs1pro-1_C PF07014.7 KLO20198.1 - 0.12 11.6 0.0 0.2 10.9 0.0 1.2 1 0 0 1 1 1 0 Hs1pro-1 protein C-terminus PPR_2 PF13041.1 KLO20201.1 - 2.6e-39 132.9 7.0 5.6e-09 35.8 0.0 8.7 5 3 5 10 10 10 7 PPR repeat family PPR_3 PF13812.1 KLO20201.1 - 5e-26 88.7 5.5 0.03 14.5 0.0 9.8 10 0 0 10 10 10 6 Pentatricopeptide repeat domain PPR_1 PF12854.2 KLO20201.1 - 1.5e-16 59.5 4.1 0.093 12.2 0.0 7.4 7 0 0 7 7 7 6 PPR repeat PPR PF01535.15 KLO20201.1 - 4.3e-15 54.5 19.5 0.0005 19.8 0.0 9.6 12 0 0 12 12 12 4 PPR repeat DASH_Dad3 PF08656.5 KLO20201.1 - 0.013 15.1 0.1 0.04 13.6 0.1 1.8 1 0 0 1 1 1 0 DASH complex subunit Dad3 Band_7 PF01145.20 KLO20202.1 - 1.5e-27 96.6 0.1 2.9e-27 95.7 0.0 1.5 2 0 0 2 2 2 1 SPFH domain / Band 7 family Band_7_1 PF13421.1 KLO20202.1 - 0.0046 16.4 0.0 0.0083 15.6 0.0 1.4 1 0 0 1 1 1 1 SPFH domain-Band 7 family Hydantoinase_B PF02538.9 KLO20202.1 - 0.072 11.3 0.3 0.13 10.4 0.2 1.5 1 1 0 1 1 1 0 Hydantoinase B/oxoprolinase GRIP PF01465.15 KLO20203.1 - 7.5e-16 57.3 1.9 2.1e-15 55.9 1.3 1.8 1 0 0 1 1 1 1 GRIP domain Filament PF00038.16 KLO20203.1 - 1.4 8.3 87.5 0.33 10.3 15.5 5.7 1 1 2 3 3 3 0 Intermediate filament protein GTP_EFTU PF00009.22 KLO20204.1 - 1.2e-60 204.1 0.4 2.1e-60 203.4 0.3 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 KLO20204.1 - 3.7e-27 94.3 0.1 9.5e-27 93.0 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 KLO20204.1 - 1.3e-18 66.8 1.6 4e-18 65.3 1.1 1.9 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 KLO20204.1 - 2.8e-06 27.2 0.1 5.3e-06 26.3 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 KLO20204.1 - 0.00038 20.9 0.1 0.00067 20.1 0.1 1.4 1 0 0 1 1 1 1 Miro-like protein cobW PF02492.14 KLO20204.1 - 0.0078 15.6 0.7 0.015 14.7 0.0 1.7 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain PduV-EutP PF10662.4 KLO20204.1 - 0.013 14.9 0.4 5.1 6.5 0.0 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation CbiA PF01656.18 KLO20204.1 - 0.088 12.1 1.5 2.5 7.4 0.0 2.3 2 0 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain DisA_N PF02457.11 KLO20204.1 - 0.092 11.8 0.0 0.22 10.6 0.0 1.6 1 1 0 1 1 1 0 DisA bacterial checkpoint controller nucleotide-binding Gtr1_RagA PF04670.7 KLO20204.1 - 0.11 11.6 0.2 0.33 10.0 0.1 1.7 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region Pex14_N PF04695.8 KLO20205.1 - 1.8e-23 83.0 6.1 6e-23 81.3 0.7 3.2 2 1 0 2 2 2 1 Peroxisomal membrane anchor protein (Pex14p) conserved region IncA PF04156.9 KLO20205.1 - 0.00038 20.0 3.7 0.00065 19.3 2.5 1.4 1 0 0 1 1 1 1 IncA protein AAA_13 PF13166.1 KLO20205.1 - 0.0035 15.8 0.4 0.0045 15.5 0.3 1.1 1 0 0 1 1 1 1 AAA domain DUF3584 PF12128.3 KLO20205.1 - 0.0061 13.9 8.9 0.0082 13.5 6.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) Laminin_II PF06009.7 KLO20205.1 - 0.023 14.4 8.3 0.046 13.4 5.7 1.4 1 0 0 1 1 1 0 Laminin Domain II RRF PF01765.14 KLO20205.1 - 0.024 14.1 9.0 0.039 13.4 6.2 1.3 1 0 0 1 1 1 0 Ribosome recycling factor NPV_P10 PF05531.7 KLO20205.1 - 0.032 14.4 5.9 0.12 12.6 0.2 2.5 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein MCPsignal PF00015.16 KLO20205.1 - 0.036 13.6 6.7 0.09 12.3 4.7 1.6 1 1 0 1 1 1 0 Methyl-accepting chemotaxis protein (MCP) signalling domain DUF677 PF05055.7 KLO20205.1 - 0.041 12.5 2.4 0.051 12.2 1.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF677) Baculo_p24 PF05073.7 KLO20205.1 - 0.11 12.0 0.9 0.21 11.1 0.6 1.4 1 0 0 1 1 1 0 Baculovirus P24 capsid protein DUF2317 PF10079.4 KLO20205.1 - 0.13 10.8 4.9 0.18 10.3 3.4 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2317) DUF3829 PF12889.2 KLO20205.1 - 0.15 11.2 4.2 0.25 10.5 2.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3829) DUF4613 PF15390.1 KLO20205.1 - 0.16 10.0 1.9 0.22 9.6 1.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4613) IFT57 PF10498.4 KLO20205.1 - 0.22 10.2 7.4 0.94 8.1 5.1 1.8 1 1 0 1 1 1 0 Intra-flagellar transport protein 57 TBPIP PF07106.8 KLO20205.1 - 0.24 10.9 8.4 0.48 9.9 5.8 1.5 1 0 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) NEP PF10167.4 KLO20205.1 - 0.31 10.7 3.5 0.6 9.8 2.5 1.4 1 0 0 1 1 1 0 Uncharacterised conserved protein Hemerythrin PF01814.18 KLO20205.1 - 0.35 11.0 5.2 8.7 6.5 0.1 2.3 1 1 1 2 2 2 0 Hemerythrin HHE cation binding domain Phlebovirus_NSM PF07246.6 KLO20205.1 - 0.38 9.8 4.5 0.55 9.3 3.1 1.2 1 0 0 1 1 1 0 Phlebovirus nonstructural protein NS-M DUF2203 PF09969.4 KLO20205.1 - 0.39 10.9 4.4 0.94 9.7 3.0 1.7 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2203) Sas10_Utp3 PF04000.10 KLO20205.1 - 0.78 9.9 4.5 14 5.9 0.7 2.4 2 0 0 2 2 2 0 Sas10/Utp3/C1D family DUF4164 PF13747.1 KLO20205.1 - 0.84 9.8 16.5 0.46 10.6 1.6 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4164) Med9 PF07544.8 KLO20205.1 - 0.93 9.2 8.5 0.18 11.5 1.3 2.5 1 1 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 DUF342 PF03961.8 KLO20205.1 - 1.1 7.6 6.6 1.8 6.8 4.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF342) DUF1664 PF07889.7 KLO20205.1 - 2.4 7.9 6.5 8.8 6.1 4.5 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Spc7 PF08317.6 KLO20205.1 - 3.7 6.1 11.4 0.5 8.9 3.6 1.9 1 1 0 1 1 1 0 Spc7 kinetochore protein Mnd1 PF03962.10 KLO20205.1 - 3.7 7.1 9.3 7.1 6.2 6.5 1.5 1 0 0 1 1 1 0 Mnd1 family Fib_alpha PF08702.5 KLO20205.1 - 4.7 7.3 6.5 15 5.6 4.6 1.7 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family COG2 PF06148.6 KLO20205.1 - 8.7 6.2 11.8 15 5.4 1.6 2.3 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 GCV_H PF01597.14 KLO20206.1 - 1.6e-42 143.9 0.3 1.9e-42 143.8 0.2 1.0 1 0 0 1 1 1 1 Glycine cleavage H-protein Biotin_lipoyl PF00364.17 KLO20206.1 - 0.00044 19.8 0.3 0.00074 19.0 0.2 1.3 1 0 0 1 1 1 1 Biotin-requiring enzyme RnfC_N PF13375.1 KLO20206.1 - 0.00061 19.4 0.2 0.001 18.7 0.1 1.3 1 0 0 1 1 1 1 RnfC Barrel sandwich hybrid domain ESSS PF10183.4 KLO20207.1 - 1.7e-26 92.6 0.6 2e-26 92.4 0.4 1.1 1 0 0 1 1 1 1 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) Sina PF03145.11 KLO20208.1 - 0.032 13.9 0.0 0.034 13.8 0.0 1.1 1 0 0 1 1 1 0 Seven in absentia protein family Fructosamin_kin PF03881.9 KLO20209.1 - 8.5e-61 205.4 0.0 9.9e-61 205.2 0.0 1.0 1 0 0 1 1 1 1 Fructosamine kinase APH PF01636.18 KLO20209.1 - 2.1e-07 30.9 0.0 3.1e-07 30.3 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.17 KLO20210.1 - 6.5e-49 165.8 0.0 9.8e-49 165.2 0.0 1.2 1 0 0 1 1 1 1 RIO1 family Rio2_N PF09202.6 KLO20210.1 - 3.9e-33 113.3 0.2 9.9e-33 112.0 0.0 1.8 2 0 0 2 2 2 1 Rio2, N-terminal APH PF01636.18 KLO20210.1 - 9.3e-11 41.9 0.3 0.00021 21.1 0.0 2.5 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.9 KLO20210.1 - 1e-07 31.2 0.0 0.011 14.7 0.0 2.2 2 0 0 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family SMN PF06003.7 KLO20210.1 - 0.011 14.8 0.4 0.017 14.2 0.3 1.2 1 0 0 1 1 1 0 Survival motor neuron protein (SMN) HTH_Crp_2 PF13545.1 KLO20210.1 - 0.045 13.5 0.0 0.12 12.2 0.0 1.7 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain Pkinase PF00069.20 KLO20210.1 - 0.089 11.9 0.3 0.31 10.1 0.2 1.8 1 1 0 1 1 1 0 Protein kinase domain Phage_rep_O PF04492.8 KLO20210.1 - 0.092 12.9 0.0 0.39 10.9 0.0 2.1 3 0 0 3 3 3 0 Bacteriophage replication protein O Nucleoplasmin PF03066.10 KLO20210.1 - 1.1 8.7 8.5 1.9 7.9 5.9 1.3 1 0 0 1 1 1 0 Nucleoplasmin TUDOR PF00567.19 KLO20211.1 - 8.8e-06 25.5 0.0 1.9e-05 24.5 0.0 1.7 1 1 0 1 1 1 1 Tudor domain Relaxase PF03432.9 KLO20211.1 - 0.0027 17.1 3.2 0.0027 17.1 2.2 1.7 2 1 0 2 2 2 1 Relaxase/Mobilisation nuclease domain DUF2839 PF10999.3 KLO20211.1 - 2.7 8.0 5.8 1.1 9.3 2.2 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2839) RicinB_lectin_2 PF14200.1 KLO20212.1 - 9.6e-09 35.5 0.9 0.00011 22.5 0.0 2.2 1 1 1 2 2 2 2 Ricin-type beta-trefoil lectin domain-like Glyco_hydro_25 PF01183.15 KLO20213.1 - 1.4e-44 152.0 0.2 1.7e-44 151.7 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 25 Sel1 PF08238.7 KLO20214.1 - 6.1e-13 48.9 17.9 9.5e-06 26.0 0.1 6.5 6 0 0 6 6 6 4 Sel1 repeat TPR_2 PF07719.12 KLO20214.1 - 0.56 10.2 6.9 0.32 11.0 0.1 3.6 4 0 0 4 4 4 0 Tetratricopeptide repeat BTB PF00651.26 KLO20218.1 - 2.7e-05 24.1 0.1 6e-05 23.0 0.1 1.7 1 1 0 1 1 1 1 BTB/POZ domain IF4E PF01652.13 KLO20219.1 - 7.6e-50 168.6 0.0 9.9e-50 168.2 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E Pil1 PF13805.1 KLO20220.1 - 2.8e-23 82.4 0.2 5.4e-23 81.5 0.2 1.4 1 0 0 1 1 1 1 Eisosome component PIL1 DUF3275 PF11679.3 KLO20220.1 - 9.9 5.7 8.6 6.8 6.2 1.1 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF3275) Mito_carr PF00153.22 KLO20221.1 - 5.7e-63 208.6 0.0 1e-19 70.0 0.0 3.6 3 1 0 3 3 3 3 Mitochondrial carrier protein YtxH PF12732.2 KLO20221.1 - 0.039 14.3 0.1 0.082 13.2 0.0 1.5 1 0 0 1 1 1 0 YtxH-like protein GYF PF02213.11 KLO20222.1 - 6e-15 54.5 0.1 1.3e-14 53.5 0.1 1.5 1 0 0 1 1 1 1 GYF domain SPX PF03105.14 KLO20222.1 - 0.055 13.2 0.0 0.055 13.2 0.0 2.1 2 1 0 2 2 2 0 SPX domain UreF PF01730.11 KLO20223.1 - 3.4e-18 66.1 0.0 7.1e-18 65.1 0.0 1.5 1 1 0 1 1 1 1 UreF Utp11 PF03998.8 KLO20224.1 - 3e-60 204.0 19.1 4.4e-60 203.5 13.2 1.2 1 0 0 1 1 1 1 Utp11 protein Glyco_hydro_16 PF00722.16 KLO20225.1 - 4.3e-09 35.9 0.5 2.7e-08 33.2 0.0 2.4 2 1 1 3 3 3 1 Glycosyl hydrolases family 16 Arm PF00514.18 KLO20226.1 - 5.7e-66 216.2 30.4 6.5e-13 47.9 0.1 12.1 12 1 1 13 13 13 8 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 KLO20226.1 - 6.2e-24 84.1 12.7 4.4e-06 26.8 0.1 7.7 2 2 5 7 7 7 6 HEAT repeats HEAT PF02985.17 KLO20226.1 - 2.5e-18 64.4 11.4 0.035 14.1 0.0 9.8 9 0 0 9 9 9 4 HEAT repeat HEAT_EZ PF13513.1 KLO20226.1 - 1.1e-14 54.4 10.2 0.03 14.8 0.2 8.3 5 2 3 8 8 8 5 HEAT-like repeat Arm_2 PF04826.8 KLO20226.1 - 5.6e-11 42.0 8.6 3.3e-07 29.6 2.1 3.0 1 1 0 2 2 2 2 Armadillo-like Adaptin_N PF01602.15 KLO20226.1 - 8.7e-10 37.5 7.2 4.4e-07 28.6 0.1 2.9 1 1 1 2 2 2 2 Adaptin N terminal region KAP PF05804.7 KLO20226.1 - 2.8e-08 32.1 2.5 4.1e-08 31.6 1.7 1.2 1 0 0 1 1 1 1 Kinesin-associated protein (KAP) V-ATPase_H_N PF03224.9 KLO20226.1 - 3.5e-08 32.9 5.9 0.015 14.4 0.0 4.8 2 1 2 4 4 4 3 V-ATPase subunit H HEAT_PBS PF03130.11 KLO20226.1 - 0.0006 20.0 5.9 48 4.8 0.1 7.4 7 0 0 7 7 7 0 PBS lyase HEAT-like repeat DUF2454 PF10521.4 KLO20226.1 - 0.0033 16.4 1.1 0.059 12.3 0.1 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF2454) IBN_N PF03810.14 KLO20226.1 - 0.01 15.7 2.3 7.2 6.5 0.2 3.6 3 1 0 3 3 3 0 Importin-beta N-terminal domain Proteasom_PSMB PF10508.4 KLO20226.1 - 0.03 12.5 7.3 0.1 10.8 3.3 2.2 1 1 1 2 2 2 0 Proteasome non-ATPase 26S subunit Vac14_Fab1_bd PF12755.2 KLO20226.1 - 0.036 14.4 0.0 3.6 8.0 0.0 3.2 2 1 2 4 4 4 0 Vacuolar 14 Fab1-binding region DKCLD PF08068.7 KLO20227.1 - 7.7e-31 105.8 0.1 3.7e-30 103.6 0.1 2.2 2 0 0 2 2 2 1 DKCLD (NUC011) domain TruB_N PF01509.13 KLO20227.1 - 1.3e-24 87.1 0.2 4.6e-21 75.5 0.1 3.5 1 1 0 1 1 1 1 TruB family pseudouridylate synthase (N terminal domain) PUA PF01472.15 KLO20227.1 - 2.2e-21 75.3 1.1 4.5e-21 74.3 0.7 1.6 1 0 0 1 1 1 1 PUA domain Ribosomal_L22e PF01776.12 KLO20228.1 - 1.6e-44 150.4 0.1 1.9e-44 150.2 0.1 1.0 1 0 0 1 1 1 1 Ribosomal L22e protein family DUF3692 PF12469.3 KLO20228.1 - 0.052 13.7 0.0 0.083 13.1 0.0 1.4 1 1 0 1 1 1 0 CRISPR-associated protein HA2 PF04408.18 KLO20229.1 - 2.1e-19 69.3 0.1 4.3e-19 68.4 0.0 1.5 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.11 KLO20229.1 - 4.1e-11 42.7 0.0 7.8e-11 41.8 0.0 1.5 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold DEAD PF00270.24 KLO20230.1 - 1.3e-06 28.0 0.1 2.4e-05 23.8 0.0 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_22 PF13401.1 KLO20230.1 - 2.6e-05 24.3 0.5 0.00014 21.9 0.1 2.4 3 0 0 3 3 3 1 AAA domain ABC_tran PF00005.22 KLO20230.1 - 0.0017 18.6 0.1 0.084 13.1 0.0 2.7 2 0 0 2 2 2 1 ABC transporter CTNNB1_binding PF08347.6 KLO20230.1 - 0.0017 18.6 0.2 0.004 17.4 0.1 1.6 1 0 0 1 1 1 1 N-terminal CTNNB1 binding NB-ARC PF00931.17 KLO20230.1 - 0.01 14.6 0.1 0.038 12.8 0.0 1.8 2 0 0 2 2 2 0 NB-ARC domain KaiC PF06745.8 KLO20230.1 - 0.036 13.1 0.0 0.062 12.4 0.0 1.3 1 0 0 1 1 1 0 KaiC AAA_16 PF13191.1 KLO20230.1 - 0.063 13.2 2.6 1.9 8.4 0.6 3.0 2 1 0 2 2 2 0 AAA ATPase domain AAA_29 PF13555.1 KLO20230.1 - 0.064 12.7 0.1 0.18 11.3 0.0 1.8 2 0 0 2 2 2 0 P-loop containing region of AAA domain SNF2_N PF00176.18 KLO20231.1 - 1.2e-71 240.9 2.0 2.1e-71 240.1 1.4 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain DBINO PF13892.1 KLO20231.1 - 3e-51 173.1 18.9 7.6e-51 171.8 13.1 1.7 1 0 0 1 1 1 1 DNA-binding domain Helicase_C PF00271.26 KLO20231.1 - 1.8e-13 50.1 0.0 4.2e-13 48.9 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HDA2-3 PF11496.3 KLO20231.1 - 2.3e-07 29.9 0.0 3e-06 26.2 0.0 2.5 2 0 0 2 2 2 1 Class II histone deacetylase complex subunits 2 and 3 ResIII PF04851.10 KLO20231.1 - 6.2e-06 26.1 0.4 1.8e-05 24.6 0.0 2.0 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DUF2924 PF11149.3 KLO20231.1 - 5 7.1 9.5 6.7 6.7 3.5 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF2924) Lyase_1 PF00206.15 KLO20232.1 - 1.7e-119 398.6 0.0 2.2e-119 398.2 0.0 1.1 1 0 0 1 1 1 1 Lyase FumaraseC_C PF10415.4 KLO20232.1 - 2.3e-19 69.1 0.0 4.7e-19 68.2 0.0 1.5 1 0 0 1 1 1 1 Fumarase C C-terminus PEX11 PF05648.9 KLO20233.1 - 4.2e-54 183.1 0.4 4.7e-54 183.0 0.2 1.0 1 0 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) Thoc2 PF11732.3 KLO20233.1 - 0.012 15.3 0.1 0.024 14.3 0.1 1.5 1 0 0 1 1 1 0 Transcription- and export-related complex subunit Cmc1 PF08583.5 KLO20234.1 - 2.7e-12 46.2 2.4 3.2e-12 46.0 1.6 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like CHCH PF06747.8 KLO20234.1 - 0.047 13.6 2.2 3.7 7.5 0.0 2.1 2 0 0 2 2 2 0 CHCH domain Radical_SAM PF04055.16 KLO20235.1 - 3.1e-12 46.9 0.0 5.3e-12 46.2 0.0 1.4 1 0 0 1 1 1 1 Radical SAM superfamily Glyco_transf_8 PF01501.15 KLO20236.1 - 7.1e-30 104.1 0.2 9.3e-30 103.7 0.1 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 8 Mannosyl_trans3 PF11051.3 KLO20236.1 - 0.07 12.4 0.1 0.17 11.2 0.1 1.6 1 1 0 1 1 1 0 Mannosyltransferase putative Peptidase_M22 PF00814.20 KLO20237.1 - 4.4e-85 285.4 0.0 5.3e-85 285.1 0.0 1.0 1 0 0 1 1 1 1 Glycoprotease family EXOSC1 PF10447.4 KLO20238.1 - 9.4e-20 70.3 0.2 1.8e-19 69.4 0.1 1.5 1 1 0 1 1 1 1 Exosome component EXOSC1/CSL4 ECR1_N PF14382.1 KLO20238.1 - 0.00054 19.1 0.0 0.0014 17.8 0.0 1.7 1 0 0 1 1 1 1 Exosome complex exonuclease RRP4 N-terminal region 2-oxoacid_dh PF00198.18 KLO20239.1 - 4.8e-81 271.4 0.0 6.1e-81 271.0 0.0 1.1 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.17 KLO20239.1 - 4.1e-20 71.1 2.0 9.5e-20 70.0 0.8 2.1 2 0 0 2 2 2 1 Biotin-requiring enzyme E3_binding PF02817.12 KLO20239.1 - 1.5e-16 59.6 0.1 3.4e-16 58.5 0.1 1.6 1 0 0 1 1 1 1 e3 binding domain Dr_adhesin PF12393.3 KLO20239.1 - 0.26 11.4 2.0 6.4 7.0 0.2 2.8 2 0 0 2 2 2 0 Dr family adhesin Epimerase PF01370.16 KLO20240.1 - 8e-19 68.0 0.0 1.2e-18 67.4 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 KLO20240.1 - 1.9e-13 49.7 0.0 2.8e-13 49.2 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 KLO20240.1 - 1.6e-11 44.5 0.3 3.2e-11 43.5 0.2 1.7 1 1 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 KLO20240.1 - 1.4e-10 40.5 0.0 3.6e-10 39.2 0.0 1.6 1 1 0 1 1 1 1 Male sterility protein adh_short PF00106.20 KLO20240.1 - 0.00099 19.0 0.1 0.01 15.7 0.0 2.5 2 1 0 2 2 2 1 short chain dehydrogenase NmrA PF05368.8 KLO20240.1 - 0.0027 16.9 0.0 0.0041 16.4 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family PsaN PF05479.6 KLO20240.1 - 0.053 13.4 0.0 0.11 12.4 0.0 1.5 1 0 0 1 1 1 0 Photosystem I reaction centre subunit N (PSAN or PSI-N) Cons_hypoth95 PF03602.10 KLO20240.1 - 0.072 12.4 0.0 0.1 11.9 0.0 1.2 1 0 0 1 1 1 0 Conserved hypothetical protein 95 DUF3473 PF11959.3 KLO20241.1 - 0.049 13.0 0.1 0.074 12.4 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3473) Es2 PF09751.4 KLO20242.1 - 1.8e-76 258.2 1.7 2.3e-76 257.8 1.1 1.1 1 0 0 1 1 1 1 Nuclear protein Es2 Integrase_DNA PF02920.10 KLO20242.1 - 0.026 13.9 0.9 0.065 12.6 0.6 1.6 1 0 0 1 1 1 0 DNA binding domain of tn916 integrase Nefa_Nip30_N PF10187.4 KLO20243.1 - 9e-23 80.3 9.4 9e-23 80.3 6.5 1.8 2 0 0 2 2 2 1 N-terminal domain of NEFA-interacting nuclear protein NIP30 AAA_25 PF13481.1 KLO20245.1 - 0.00092 18.6 0.0 0.0017 17.8 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 KLO20245.1 - 0.083 12.6 0.0 0.19 11.4 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain Rad51 PF08423.6 KLO20245.1 - 0.1 11.4 0.0 2.6 6.9 0.0 2.2 2 0 0 2 2 2 0 Rad51 AAA_11 PF13086.1 KLO20245.1 - 0.15 11.6 0.0 0.21 11.1 0.0 1.2 1 0 0 1 1 1 0 AAA domain RecA PF00154.16 KLO20245.1 - 0.19 10.7 0.0 0.29 10.1 0.0 1.2 1 0 0 1 1 1 0 recA bacterial DNA recombination protein SLX9 PF15341.1 KLO20246.1 - 3.2e-21 76.0 6.3 4.7e-21 75.4 4.4 1.3 1 0 0 1 1 1 1 Ribosome biogenesis protein SLX9 PTS_IIA PF02255.11 KLO20246.1 - 0.17 11.7 1.9 0.18 11.6 0.1 1.9 2 0 0 2 2 2 0 PTS system, Lactose/Cellobiose specific IIA subunit DUF3043 PF11241.3 KLO20246.1 - 0.94 9.0 5.3 1 8.9 0.8 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3043) DUF914 PF06027.7 KLO20248.1 - 5.8e-10 38.5 10.6 1.5e-06 27.3 3.2 3.1 2 1 0 3 3 3 3 Eukaryotic protein of unknown function (DUF914) EamA PF00892.15 KLO20248.1 - 1.5e-08 34.7 31.6 1.7e-08 34.5 2.2 3.0 3 0 0 3 3 3 2 EamA-like transporter family EmrE PF13536.1 KLO20248.1 - 6.6e-05 23.0 0.5 6.6e-05 23.0 0.3 3.7 3 1 0 3 3 3 1 Multidrug resistance efflux transporter TPT PF03151.11 KLO20248.1 - 0.0041 16.7 2.5 0.0041 16.7 1.7 2.6 3 0 0 3 3 3 2 Triose-phosphate Transporter family UAA PF08449.6 KLO20248.1 - 0.028 13.3 11.4 0.024 13.5 6.6 1.8 2 0 0 2 2 2 0 UAA transporter family TauD PF02668.11 KLO20249.1 - 8.5e-51 173.0 0.0 1.2e-50 172.6 0.0 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DUF971 PF06155.7 KLO20249.1 - 0.0041 17.4 0.0 0.034 14.5 0.1 2.1 1 1 1 2 2 2 1 Protein of unknown function (DUF971) CsiD PF08943.5 KLO20249.1 - 0.061 12.2 0.0 0.13 11.0 0.0 1.5 2 0 0 2 2 2 0 CsiD AMP-binding PF00501.23 KLO20250.1 - 7.9e-26 90.3 0.0 1.2e-24 86.5 0.0 2.0 1 1 0 1 1 1 1 AMP-binding enzyme GH3 PF03321.8 KLO20250.1 - 0.025 13.1 0.1 0.038 12.5 0.1 1.2 1 0 0 1 1 1 0 GH3 auxin-responsive promoter PPR_2 PF13041.1 KLO20252.1 - 6.8e-19 67.5 0.0 2e-05 24.4 0.0 6.6 6 0 0 6 6 6 3 PPR repeat family PPR PF01535.15 KLO20252.1 - 1.3e-11 43.5 0.0 3.2e-05 23.6 0.0 5.8 6 0 0 6 6 6 2 PPR repeat PPR_3 PF13812.1 KLO20252.1 - 1.3e-10 40.6 15.5 3.3e-05 23.8 0.0 7.7 8 0 0 8 8 8 3 Pentatricopeptide repeat domain PPR_1 PF12854.2 KLO20252.1 - 2.5e-07 30.0 0.0 0.015 14.7 0.0 5.1 5 0 0 5 5 5 1 PPR repeat TPR_14 PF13428.1 KLO20252.1 - 0.022 15.3 8.7 0.27 11.9 0.0 5.3 4 1 1 5 5 5 0 Tetratricopeptide repeat Hap4_Hap_bind PF10297.4 KLO20253.1 - 1.1e-08 34.6 3.5 2.5e-08 33.4 2.4 1.7 1 0 0 1 1 1 1 Minimal binding motif of Hap4 for binding to Hap2/3/5 bZIP_1 PF00170.16 KLO20253.1 - 1.8e-08 34.2 17.4 4.1e-05 23.4 3.2 2.4 2 0 0 2 2 2 2 bZIP transcription factor bZIP_2 PF07716.10 KLO20253.1 - 0.001 18.8 16.9 0.03 14.1 2.6 2.5 2 0 0 2 2 2 2 Basic region leucine zipper DUF904 PF06005.7 KLO20253.1 - 0.0028 17.9 9.1 0.0056 16.9 6.3 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF904) HALZ PF02183.13 KLO20253.1 - 0.0065 16.1 4.2 0.019 14.6 2.9 1.7 1 0 0 1 1 1 1 Homeobox associated leucine zipper DUF972 PF06156.8 KLO20253.1 - 0.14 12.4 5.4 0.3 11.4 3.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF972) Seadorna_VP6 PF07407.6 KLO20253.1 - 0.29 9.8 0.0 0.83 8.3 0.3 1.4 2 0 0 2 2 2 0 Seadornavirus VP6 protein Herpes_UL6 PF01763.11 KLO20253.1 - 2.3 6.2 6.1 3.3 5.7 4.2 1.1 1 0 0 1 1 1 0 Herpesvirus UL6 like IncA PF04156.9 KLO20253.1 - 2.3 7.7 9.7 4.3 6.8 6.7 1.4 1 0 0 1 1 1 0 IncA protein HAUS6_N PF14661.1 KLO20253.1 - 9.7 5.4 12.5 17 4.6 8.7 1.3 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus eIF2A PF08662.6 KLO20254.1 - 2.6e-40 138.2 0.1 1.3e-22 80.5 0.0 4.1 3 2 0 3 3 3 3 Eukaryotic translation initiation factor eIF2A RRM_6 PF14259.1 KLO20254.1 - 2.4e-08 33.8 0.1 1.4e-07 31.3 0.0 2.3 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 KLO20254.1 - 1.1e-07 31.3 0.0 3e-07 29.9 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) WD40 PF00400.27 KLO20254.1 - 3.3e-05 23.5 0.2 0.084 12.7 0.0 4.9 6 0 0 6 6 6 1 WD domain, G-beta repeat RRM_5 PF13893.1 KLO20254.1 - 0.0002 21.1 0.0 0.0009 19.0 0.0 2.1 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Sugar_tr PF00083.19 KLO20255.1 - 2.1e-41 141.9 28.8 6.1e-39 133.8 20.0 2.0 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KLO20255.1 - 1.1e-16 60.5 38.7 7.1e-10 38.1 12.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2834 PF11196.3 KLO20255.1 - 0.036 14.2 3.7 1.2 9.2 0.5 3.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2834) SLS PF14611.1 KLO20256.1 - 2.2e-13 50.1 0.1 9.2e-13 48.0 0.0 2.0 2 0 0 2 2 2 1 Mitochondrial inner-membrane-bound regulator Spb1_C PF07780.7 KLO20257.1 - 8.8e-69 231.2 22.2 8.8e-69 231.2 15.4 3.8 3 1 0 4 4 4 1 Spb1 C-terminal domain FtsJ PF01728.14 KLO20257.1 - 5.3e-53 179.7 0.2 1.3e-52 178.3 0.0 1.8 2 0 0 2 2 2 1 FtsJ-like methyltransferase DUF3381 PF11861.3 KLO20257.1 - 3.3e-50 169.7 4.7 3.3e-50 169.7 3.3 4.4 4 0 0 4 4 4 1 Domain of unknown function (DUF3381) UPF0181 PF03701.9 KLO20257.1 - 0.034 13.4 5.7 0.089 12.1 0.1 2.9 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0181) PAXNEB PF05625.6 KLO20258.1 - 2.8e-53 181.0 0.0 1.3e-52 178.8 0.0 1.8 1 1 0 1 1 1 1 PAXNEB protein KaiC PF06745.8 KLO20258.1 - 0.067 12.2 0.0 0.13 11.3 0.0 1.4 1 0 0 1 1 1 0 KaiC Exo_endo_phos PF03372.18 KLO20260.1 - 1.7e-23 83.8 0.0 2.2e-23 83.4 0.0 1.1 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family B3 PF02362.16 KLO20260.1 - 0.03 13.9 0.0 0.057 13.0 0.0 1.4 1 0 0 1 1 1 0 B3 DNA binding domain RhoGEF PF00621.15 KLO20261.1 - 1.6e-20 73.7 0.0 2.2e-20 73.2 0.0 1.2 1 0 0 1 1 1 1 RhoGEF domain HMG_box_2 PF09011.5 KLO20261.1 - 0.12 12.7 0.3 0.24 11.7 0.2 1.4 1 0 0 1 1 1 0 HMG-box domain ACP PF06857.6 KLO20261.1 - 0.18 11.7 0.1 0.38 10.7 0.1 1.5 1 0 0 1 1 1 0 Malonate decarboxylase delta subunit (MdcD) Peptidase_M16_C PF05193.16 KLO20262.1 - 7.9e-16 58.2 0.0 1.7e-08 34.3 0.0 2.5 2 0 0 2 2 2 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.15 KLO20262.1 - 1.5e-10 41.0 0.1 6.2e-10 39.0 0.0 2.0 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Pou PF00157.12 KLO20262.1 - 0.13 11.8 0.0 0.5 10.0 0.0 2.0 1 1 0 1 1 1 0 Pou domain - N-terminal to homeobox domain DUF506 PF04720.7 KLO20262.1 - 0.28 10.7 0.0 0.28 10.7 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF506) NUFIP1 PF10453.4 KLO20263.1 - 2.7e-15 55.5 0.2 5.5e-15 54.6 0.2 1.6 1 0 0 1 1 1 1 Nuclear fragile X mental retardation-interacting protein 1 (NUFIP1) DUF1644 PF07800.7 KLO20263.1 - 0.039 13.8 1.6 0.044 13.6 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1644) Ribosomal_L13 PF00572.13 KLO20264.1 - 1.8e-27 95.9 0.0 3e-27 95.2 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L13 RasGEF PF00617.14 KLO20265.1 - 2.4e-26 92.6 0.1 6.5e-26 91.2 0.1 1.7 1 1 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.15 KLO20265.1 - 1e-11 44.8 0.0 2.6e-11 43.5 0.0 1.6 1 0 0 1 1 1 1 RasGEF N-terminal motif Miro PF08477.8 KLO20265.1 - 1.3e-06 28.8 0.0 3.1e-06 27.6 0.0 1.7 1 0 0 1 1 1 1 Miro-like protein AAA_16 PF13191.1 KLO20265.1 - 0.0045 17.0 0.1 0.012 15.5 0.1 1.7 1 0 0 1 1 1 1 AAA ATPase domain Viral_helicase1 PF01443.13 KLO20265.1 - 0.0082 15.6 0.0 0.017 14.6 0.0 1.5 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase AAA_22 PF13401.1 KLO20265.1 - 0.033 14.3 0.0 0.079 13.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain DUF258 PF03193.11 KLO20265.1 - 0.047 12.8 0.1 0.096 11.8 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_33 PF13671.1 KLO20265.1 - 0.057 13.2 0.0 0.16 11.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain Septin PF00735.13 KLO20265.1 - 0.097 11.6 0.0 0.21 10.5 0.0 1.4 1 0 0 1 1 1 0 Septin SurE PF01975.12 KLO20266.1 - 7.6e-45 152.6 0.0 1.3e-44 151.8 0.0 1.3 1 0 0 1 1 1 1 Survival protein SurE SSP160 PF06933.6 KLO20266.1 - 1.5 6.6 4.4 2.2 6.1 3.1 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Glyco_hydro_16 PF00722.16 KLO20267.1 - 1.8e-10 40.3 0.5 3.6e-10 39.4 0.0 1.7 2 0 0 2 2 2 1 Glycosyl hydrolases family 16 CTV_P6 PF06706.6 KLO20269.1 - 0.091 12.2 0.1 0.091 12.2 0.1 2.3 3 0 0 3 3 3 0 Citrus tristeza virus 6-kDa protein DUF3938 PF13074.1 KLO20269.1 - 0.11 12.2 1.5 0.34 10.7 1.0 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF3938) Actin PF00022.14 KLO20271.1 - 1.5e-129 431.9 0.0 1.7e-129 431.6 0.0 1.0 1 0 0 1 1 1 1 Actin Ribosomal_L15e PF00827.12 KLO20272.1 - 2.4e-91 304.4 11.6 2.7e-91 304.2 8.0 1.0 1 0 0 1 1 1 1 Ribosomal L15 Tic20 PF09685.5 KLO20273.1 - 7.1e-07 29.1 1.0 8.7e-07 28.8 0.7 1.1 1 0 0 1 1 1 1 Tic20-like protein Ribosomal_S24e PF01282.14 KLO20274.1 - 5.7e-34 115.7 0.1 5.7e-34 115.7 0.0 1.5 2 0 0 2 2 2 1 Ribosomal protein S24e GPI2 PF06432.6 KLO20275.1 - 3.6e-85 285.7 14.5 4.1e-85 285.5 10.0 1.0 1 0 0 1 1 1 1 Phosphatidylinositol N-acetylglucosaminyltransferase Med12-LCEWAV PF12145.3 KLO20275.1 - 0.19 10.1 0.3 0.28 9.6 0.2 1.1 1 0 0 1 1 1 0 Eukaryotic Mediator 12 subunit domain bZIP_1 PF00170.16 KLO20276.1 - 1.2e-05 25.1 5.4 1.4e-05 24.9 2.5 2.0 1 1 1 2 2 2 2 bZIP transcription factor TBPIP PF07106.8 KLO20276.1 - 0.0024 17.4 0.4 0.0041 16.6 0.2 1.2 1 0 0 1 1 1 1 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Rootletin PF15035.1 KLO20276.1 - 0.0025 17.8 3.7 0.0042 17.0 2.6 1.3 1 0 0 1 1 1 1 Ciliary rootlet component, centrosome cohesion IncA PF04156.9 KLO20276.1 - 0.0098 15.5 5.2 0.014 14.9 3.6 1.2 1 0 0 1 1 1 1 IncA protein ATG16 PF08614.6 KLO20276.1 - 0.012 15.4 6.2 0.026 14.3 4.3 1.5 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) DUF148 PF02520.12 KLO20276.1 - 0.047 13.4 0.8 0.077 12.7 0.6 1.3 1 0 0 1 1 1 0 Domain of unknown function DUF148 DUF972 PF06156.8 KLO20276.1 - 0.051 13.9 0.3 0.1 12.9 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF972) APG6 PF04111.7 KLO20276.1 - 0.06 12.3 2.3 0.086 11.8 1.6 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 SlyX PF04102.7 KLO20276.1 - 0.083 13.2 1.3 0.38 11.1 0.9 2.1 1 0 0 1 1 1 0 SlyX AAA_13 PF13166.1 KLO20276.1 - 0.11 10.9 2.2 0.15 10.4 1.5 1.1 1 0 0 1 1 1 0 AAA domain Dzip-like_N PF13815.1 KLO20276.1 - 0.12 12.1 0.5 0.22 11.3 0.4 1.4 1 0 0 1 1 1 0 Iguana/Dzip1-like DAZ-interacting protein N-terminal bZIP_2 PF07716.10 KLO20276.1 - 0.15 11.9 10.5 0.1 12.4 0.4 2.8 2 1 1 3 3 2 0 Basic region leucine zipper TMF_DNA_bd PF12329.3 KLO20276.1 - 0.16 11.8 2.9 0.14 12.0 1.0 1.6 1 1 0 1 1 1 0 TATA element modulatory factor 1 DNA binding Fib_alpha PF08702.5 KLO20276.1 - 0.19 11.8 0.7 0.33 11.0 0.5 1.4 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family Atg14 PF10186.4 KLO20276.1 - 1.3 7.8 8.9 2 7.2 6.2 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 HAUS6_N PF14661.1 KLO20276.1 - 3.3 6.9 5.8 5.3 6.3 4.0 1.2 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus Apc4 PF12896.2 KLO20277.1 - 1e-28 100.1 0.0 1.9e-28 99.2 0.0 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 4 IKI3 PF04762.7 KLO20277.1 - 0.21 9.3 0.0 0.28 8.9 0.0 1.1 1 0 0 1 1 1 0 IKI3 family DEAD PF00270.24 KLO20278.1 - 5.2e-46 156.2 0.0 3.2e-45 153.6 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KLO20278.1 - 1e-23 82.9 0.0 2.2e-23 81.9 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 KLO20278.1 - 0.001 18.9 7.5 0.013 15.3 0.0 3.2 3 1 0 3 3 3 1 Type III restriction enzyme, res subunit AAA_22 PF13401.1 KLO20278.1 - 0.013 15.6 0.1 0.062 13.4 0.1 2.2 1 1 0 1 1 1 0 AAA domain KIP1 PF07765.7 KLO20278.1 - 0.064 13.1 0.8 0.16 11.7 0.6 1.7 1 0 0 1 1 1 0 KIP1-like protein DPBB_1 PF03330.13 KLO20281.1 - 0.018 15.0 0.0 0.055 13.4 0.0 1.8 1 1 0 1 1 1 0 Rare lipoprotein A (RlpA)-like double-psi beta-barrel IER PF05760.7 KLO20281.1 - 0.21 11.4 3.5 0.28 11.0 2.4 1.2 1 0 0 1 1 1 0 Immediate early response protein (IER) CDC27 PF09507.5 KLO20281.1 - 0.39 9.9 6.7 0.52 9.4 4.7 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 DUF1183 PF06682.7 KLO20281.1 - 1 8.8 7.1 0.13 11.8 1.9 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1183) SAD_SRA PF02182.12 KLO20282.1 - 1.3e-40 138.2 0.0 2.6e-40 137.2 0.0 1.5 1 0 0 1 1 1 1 SAD/SRA domain SNARE PF05739.14 KLO20283.1 - 0.00016 21.3 3.7 0.00016 21.3 2.6 2.6 3 0 0 3 3 3 1 SNARE domain Mpp10 PF04006.7 KLO20284.1 - 2.3e-99 333.4 76.6 2.7e-98 329.9 53.0 2.2 1 1 0 1 1 1 1 Mpp10 protein Lyase_8 PF02278.13 KLO20285.1 - 3.8e-25 88.7 0.1 7e-25 87.9 0.1 1.3 1 0 0 1 1 1 1 Polysaccharide lyase family 8, super-sandwich domain Lyase_8_N PF08124.6 KLO20285.1 - 2.1e-23 82.7 0.0 3.2e-23 82.1 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide lyase family 8, N terminal alpha-helical domain DUF515 PF04415.7 KLO20285.1 - 7.7 4.6 8.9 15 3.6 6.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF515) Claudin_2 PF13903.1 KLO20286.1 - 0.00042 20.0 2.4 0.00042 20.0 1.7 1.9 1 1 0 2 2 2 1 PMP-22/EMP/MP20/Claudin tight junction zf-C2H2 PF00096.21 KLO20287.1 - 0.028 14.7 1.8 0.028 14.7 1.2 7.1 6 1 0 7 7 7 0 Zinc finger, C2H2 type PBP1_TM PF14812.1 KLO20287.1 - 0.03 14.6 0.3 0.073 13.3 0.2 1.6 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal zf-met PF12874.2 KLO20287.1 - 0.058 13.6 0.8 0.058 13.6 0.5 6.0 6 1 2 8 8 8 0 Zinc-finger of C2H2 type IRF PF00605.12 KLO20287.1 - 2.1 8.1 5.1 3.3 7.5 0.7 2.3 1 1 1 2 2 2 0 Interferon regulatory factor transcription factor Ribosomal_S3_C PF00189.15 KLO20288.1 - 5.3e-17 61.8 0.0 1.2e-16 60.6 0.0 1.6 2 0 0 2 2 2 1 Ribosomal protein S3, C-terminal domain KH_2 PF07650.12 KLO20288.1 - 3.5e-11 42.5 0.0 5.9e-11 41.7 0.0 1.4 1 0 0 1 1 1 1 KH domain Amidase PF01425.16 KLO20289.1 - 3.2e-103 345.9 0.0 3.7e-103 345.7 0.0 1.0 1 0 0 1 1 1 1 Amidase Lipase3_N PF03893.11 KLO20290.1 - 0.07 12.9 0.3 0.15 11.8 0.2 1.6 1 0 0 1 1 1 0 Lipase 3 N-terminal region SprB PF13573.1 KLO20291.1 - 0.064 12.8 11.2 0.68 9.5 1.6 2.8 2 0 0 2 2 2 0 SprB repeat Thiolase_N PF00108.18 KLO20292.1 - 8.5e-66 221.6 0.0 1.8e-65 220.5 0.0 1.5 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 KLO20292.1 - 5.2e-42 142.1 1.0 1e-41 141.2 0.2 1.9 2 0 0 2 2 2 1 Thiolase, C-terminal domain ACP_syn_III PF08545.5 KLO20292.1 - 0.039 13.6 1.2 7 6.3 0.0 3.0 3 0 0 3 3 3 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Glycolytic PF00274.14 KLO20293.1 - 3.4e-74 249.3 0.0 4.4e-74 248.9 0.0 1.1 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-I ACC_epsilon PF13822.1 KLO20293.1 - 0.23 11.8 0.2 0.23 11.8 0.1 2.6 3 0 0 3 3 3 0 Acyl-CoA carboxylase epsilon subunit Pectinesterase PF01095.14 KLO20294.1 - 2.1e-35 121.7 2.7 2.7e-35 121.3 1.9 1.1 1 0 0 1 1 1 1 Pectinesterase MVP_shoulder PF11978.3 KLO20294.1 - 0.097 12.5 0.2 0.31 10.9 0.1 1.7 2 0 0 2 2 2 0 Shoulder domain Ribosomal_L32p PF01783.18 KLO20295.1 - 2.1e-16 59.8 4.6 2.7e-16 59.4 3.2 1.1 1 0 0 1 1 1 1 Ribosomal L32p protein family Prok-RING_1 PF14446.1 KLO20295.1 - 0.0047 16.6 1.2 0.0078 15.9 0.8 1.4 1 1 0 1 1 1 1 Prokaryotic RING finger family 1 Stc1 PF12898.2 KLO20295.1 - 0.021 14.8 0.8 0.027 14.5 0.5 1.1 1 0 0 1 1 1 0 Stc1 domain DZR PF12773.2 KLO20295.1 - 0.035 13.9 0.6 0.05 13.4 0.4 1.3 1 0 0 1 1 1 0 Double zinc ribbon GFA PF04828.9 KLO20295.1 - 0.057 13.3 1.4 0.68 9.9 0.1 2.0 1 1 1 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme Zn-ribbon_8 PF09723.5 KLO20295.1 - 0.2 11.6 1.6 0.72 9.8 1.1 1.9 1 1 0 1 1 1 0 Zinc ribbon domain Auto_anti-p27 PF06677.7 KLO20295.1 - 0.42 10.4 0.3 0.42 10.4 0.2 1.8 1 1 1 2 2 2 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) Tnp_zf-ribbon_2 PF13842.1 KLO20295.1 - 1.2 9.6 3.8 1.6 9.1 2.6 1.4 1 1 0 1 1 1 0 DDE_Tnp_1-like zinc-ribbon zf-ribbon_3 PF13248.1 KLO20295.1 - 1.5 8.0 4.6 3.5 6.9 3.2 1.6 1 1 0 1 1 1 0 zinc-ribbon domain DUF678 PF05077.7 KLO20295.1 - 3 7.8 5.3 1.2 9.1 0.2 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF678) ETC_C1_NDUFA5 PF04716.9 KLO20296.1 - 2.5e-17 62.1 0.1 3.9e-17 61.5 0.1 1.3 1 0 0 1 1 1 1 ETC complex I subunit conserved region APH PF01636.18 KLO20296.1 - 0.14 11.8 0.0 0.14 11.8 0.0 1.1 1 0 0 1 1 1 0 Phosphotransferase enzyme family Stm1_N PF09598.5 KLO20297.1 - 0.0012 19.5 0.6 0.0012 19.5 0.4 5.2 4 1 0 4 4 4 1 Stm1 HABP4_PAI-RBP1 PF04774.10 KLO20297.1 - 0.0077 16.7 17.3 0.0077 16.7 12.0 4.6 4 1 1 5 5 5 1 Hyaluronan / mRNA binding family HALZ PF02183.13 KLO20299.1 - 0.45 10.2 2.0 4.2 7.1 0.1 2.2 2 0 0 2 2 2 0 Homeobox associated leucine zipper DUF3419 PF11899.3 KLO20300.1 - 1.4e-122 409.1 0.0 2.2e-122 408.4 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3419) Methyltransf_23 PF13489.1 KLO20300.1 - 8.2e-09 35.3 0.0 5.7e-07 29.3 0.0 2.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 KLO20300.1 - 3e-05 24.5 0.0 0.0014 19.1 0.0 2.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 KLO20300.1 - 0.00015 22.2 0.0 0.0056 17.1 0.0 2.9 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_25 PF13649.1 KLO20300.1 - 0.0004 20.7 0.0 0.002 18.4 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.13 KLO20300.1 - 0.00046 19.3 0.0 0.001 18.2 0.0 1.5 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.7 KLO20300.1 - 0.00067 20.0 0.0 0.011 16.1 0.0 2.7 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_26 PF13659.1 KLO20300.1 - 0.001 19.1 0.1 0.066 13.2 0.0 2.7 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_4 PF02390.12 KLO20300.1 - 0.018 14.0 0.0 0.058 12.4 0.0 1.7 2 0 0 2 2 2 0 Putative methyltransferase Methyltransf_31 PF13847.1 KLO20300.1 - 0.021 14.4 0.0 0.049 13.2 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain KTI12 PF08433.5 KLO20303.1 - 6.8e-74 248.4 0.0 8.5e-74 248.1 0.0 1.1 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_33 PF13671.1 KLO20303.1 - 3.7e-09 36.6 0.0 6.2e-09 35.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 KLO20303.1 - 0.0045 17.2 0.1 0.011 16.1 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 KLO20303.1 - 0.073 13.2 0.0 0.22 11.6 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.1 KLO20303.1 - 0.1 13.3 0.1 0.19 12.5 0.0 1.6 2 0 0 2 2 2 0 AAA domain Pam16 PF03656.8 KLO20304.1 - 2.9e-18 65.8 1.3 1.4e-17 63.6 0.9 1.9 1 1 0 1 1 1 1 Pam16 ATP-synt_C PF00137.16 KLO20305.1 - 6e-28 96.5 25.9 2.3e-16 59.4 5.4 2.5 3 0 0 3 3 3 2 ATP synthase subunit C G0-G1_switch_2 PF15103.1 KLO20305.1 - 0.006 16.7 0.3 0.46 10.7 0.1 2.3 2 0 0 2 2 2 1 G0/G1 switch protein 2 Cation_efflux PF01545.16 KLO20305.1 - 0.04 12.9 0.1 0.04 12.9 0.1 2.6 3 0 0 3 3 3 0 Cation efflux family Yippee-Mis18 PF03226.9 KLO20306.1 - 1.7e-16 60.0 0.1 2.3e-16 59.6 0.1 1.1 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly SNF2_N PF00176.18 KLO20308.1 - 4.5e-68 229.2 0.7 6.8e-68 228.6 0.5 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain DUF4208 PF13907.1 KLO20308.1 - 9.4e-25 86.7 1.9 1.1e-24 86.5 0.1 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF4208) Chromo PF00385.19 KLO20308.1 - 1.7e-18 65.9 1.3 1.4e-13 50.2 0.2 3.2 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain Helicase_C PF00271.26 KLO20308.1 - 8.9e-15 54.3 0.0 2.2e-14 53.0 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain TBP PF00352.16 KLO20308.1 - 0.018 14.3 0.0 0.045 13.1 0.0 1.6 1 0 0 1 1 1 0 Transcription factor TFIID (or TATA-binding protein, TBP) AAA_22 PF13401.1 KLO20308.1 - 0.061 13.4 0.2 0.34 11.0 0.0 2.4 2 1 0 2 2 2 0 AAA domain YjgP_YjgQ PF03739.9 KLO20309.1 - 0.011 14.5 0.0 0.095 11.4 0.0 2.1 2 0 0 2 2 2 0 Predicted permease YjgP/YjgQ family RskA PF10099.4 KLO20309.1 - 0.016 14.9 0.0 0.031 13.9 0.0 1.4 1 0 0 1 1 1 0 Anti-sigma-K factor rskA DUF805 PF05656.9 KLO20309.1 - 0.076 12.8 0.1 0.13 12.0 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF805) zf-SNAP50_C PF12251.3 KLO20310.1 - 3.2e-30 104.9 0.0 4.5e-30 104.4 0.0 1.2 1 0 0 1 1 1 1 snRNA-activating protein of 50kDa MW C terminal Ecl1 PF12855.2 KLO20313.1 - 1.2e-07 30.9 0.1 0.00058 19.1 0.0 2.4 2 0 0 2 2 2 2 Life-span regulatory factor PP_kinase_N PF13089.1 KLO20313.1 - 0.11 12.5 0.0 30 4.7 0.0 2.5 2 0 0 2 2 2 0 Polyphosphate kinase N-terminal domain TFIIA PF03153.8 KLO20313.1 - 2.9 7.6 10.7 7.9 6.2 7.4 1.7 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Striatin PF08232.7 KLO20314.1 - 0.043 14.1 23.5 0.25 11.6 4.5 2.8 1 1 1 2 2 2 0 Striatin family NPV_P10 PF05531.7 KLO20314.1 - 0.043 14.0 1.5 10 6.4 0.0 2.5 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Fib_alpha PF08702.5 KLO20314.1 - 0.45 10.6 14.8 0.049 13.7 4.2 2.2 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family AAA_13 PF13166.1 KLO20314.1 - 3.4 6.0 18.6 6.3 5.1 12.9 1.3 1 0 0 1 1 1 0 AAA domain NIF PF03031.13 KLO20315.1 - 1.7e-52 177.2 0.1 1.9e-52 177.0 0.1 1.0 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase HAD_2 PF13419.1 KLO20315.1 - 0.035 14.3 0.1 0.87 9.7 0.0 2.0 1 1 1 2 2 2 0 Haloacid dehalogenase-like hydrolase ATP-sulfurylase PF01747.12 KLO20316.1 - 5.2e-85 284.1 0.1 7e-85 283.7 0.1 1.2 1 0 0 1 1 1 1 ATP-sulfurylase PUA_2 PF14306.1 KLO20316.1 - 4.4e-55 185.4 0.0 7.4e-55 184.7 0.0 1.4 1 0 0 1 1 1 1 PUA-like domain APS_kinase PF01583.15 KLO20316.1 - 6.6e-52 175.3 0.0 9.8e-52 174.7 0.0 1.3 1 0 0 1 1 1 1 Adenylylsulphate kinase SHS2_Rpb7-N PF03876.12 KLO20317.1 - 1.7e-07 31.2 0.0 2.9e-07 30.4 0.0 1.4 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 CAF-1_p150 PF11600.3 KLO20317.1 - 0.0015 17.9 38.1 0.0015 17.9 26.4 2.2 2 0 0 2 2 2 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal DUF4629 PF15442.1 KLO20317.1 - 0.37 10.9 29.7 0.19 11.8 12.6 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4629) GAGA_bind PF06217.7 KLO20317.1 - 1.6 8.6 23.4 0.51 10.2 9.4 2.2 2 0 0 2 2 2 0 GAGA binding protein-like family SprA-related PF12118.3 KLO20317.1 - 2.1 7.5 26.0 0.023 14.0 9.9 2.1 2 0 0 2 2 2 0 SprA-related family DUF2828 PF11443.3 KLO20317.1 - 2.4 6.2 13.2 4.3 5.4 5.3 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF2828) Arf PF00025.16 KLO20318.1 - 4.6e-37 126.9 0.0 8.6e-37 126.0 0.0 1.4 1 1 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.15 KLO20318.1 - 4.8e-12 45.2 0.0 4.6e-07 28.8 0.0 2.3 1 1 1 2 2 2 2 G-protein alpha subunit Miro PF08477.8 KLO20318.1 - 3.1e-07 30.8 0.0 4.9e-07 30.2 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Ras PF00071.17 KLO20318.1 - 6.3e-06 25.6 0.0 9.5e-06 25.0 0.0 1.3 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.7 KLO20318.1 - 0.00028 20.1 0.0 0.00037 19.7 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.5 KLO20318.1 - 0.00053 19.2 0.0 0.00076 18.7 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.18 KLO20318.1 - 0.0029 17.5 0.0 0.0051 16.7 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_22 PF13401.1 KLO20318.1 - 0.0054 16.8 0.0 0.011 15.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.22 KLO20318.1 - 0.045 14.0 0.1 0.089 13.0 0.0 1.5 1 0 0 1 1 1 0 ABC transporter Thymidylate_kin PF02223.12 KLO20318.1 - 0.056 12.8 0.1 0.093 12.1 0.0 1.4 1 0 0 1 1 1 0 Thymidylate kinase AAA_33 PF13671.1 KLO20318.1 - 0.064 13.1 0.1 0.11 12.4 0.0 1.5 1 1 0 1 1 1 0 AAA domain cobW PF02492.14 KLO20318.1 - 0.065 12.6 0.0 2.3 7.6 0.1 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain SRP54 PF00448.17 KLO20318.1 - 0.071 12.5 0.0 0.12 11.8 0.0 1.3 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_23 PF13476.1 KLO20318.1 - 0.12 12.6 0.3 0.14 12.4 0.2 1.4 1 1 0 1 1 1 0 AAA domain KAP_NTPase PF07693.9 KLO20318.1 - 0.14 11.1 0.0 0.15 11.0 0.0 1.1 1 0 0 1 1 1 0 KAP family P-loop domain AAA_29 PF13555.1 KLO20318.1 - 0.14 11.7 0.0 0.27 10.8 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain adh_short PF00106.20 KLO20319.1 - 4.3e-24 85.3 0.1 6.7e-24 84.6 0.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KLO20319.1 - 4.5e-12 46.2 0.0 7.8e-12 45.4 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 KLO20319.1 - 9.7e-09 35.1 0.3 7.5e-08 32.2 0.2 2.0 1 1 0 1 1 1 1 KR domain Eno-Rase_NADH_b PF12242.3 KLO20319.1 - 0.027 14.2 2.4 0.12 12.1 0.3 2.6 3 0 0 3 3 3 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase B12-binding PF02310.14 KLO20319.1 - 0.03 14.1 0.1 0.059 13.2 0.1 1.4 1 0 0 1 1 1 0 B12 binding domain DUF3996 PF13161.1 KLO20319.1 - 0.096 12.3 0.0 2.5 7.7 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3996) AdoHcyase_NAD PF00670.16 KLO20319.1 - 0.51 10.1 2.8 0.88 9.3 1.1 2.0 2 1 0 2 2 2 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Voltage_CLC PF00654.15 KLO20320.1 - 2.1e-92 309.8 34.0 2.1e-92 309.8 23.6 1.6 2 0 0 2 2 2 1 Voltage gated chloride channel CBS PF00571.23 KLO20320.1 - 2.3e-10 40.0 0.6 8.2e-06 25.5 0.0 2.5 2 0 0 2 2 2 2 CBS domain F-box-like PF12937.2 KLO20321.1 - 0.00062 19.4 0.1 0.0032 17.1 0.0 2.3 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 KLO20321.1 - 0.0019 17.8 0.1 0.012 15.2 0.0 2.4 2 0 0 2 2 2 1 F-box domain PIG-U PF06728.8 KLO20322.1 - 6.4e-102 341.2 25.7 7.3e-102 341.0 17.8 1.0 1 0 0 1 1 1 1 GPI transamidase subunit PIG-U 2TM PF13239.1 KLO20322.1 - 9.1 6.4 8.5 53 3.9 5.7 2.5 1 1 1 2 2 2 0 2TM domain Hydrophobin PF01185.13 KLO20323.1 - 3.5e-18 65.8 9.0 4.3e-18 65.5 6.2 1.1 1 0 0 1 1 1 1 Fungal hydrophobin Hydrophobin PF01185.13 KLO20324.1 - 7e-20 71.2 9.2 8.2e-20 71.0 6.4 1.0 1 0 0 1 1 1 1 Fungal hydrophobin CPSase_sm_chain PF00988.17 KLO20325.1 - 1.9e-44 150.3 0.0 3.2e-44 149.5 0.0 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain GATase PF00117.23 KLO20325.1 - 1.4e-34 119.2 0.0 2e-34 118.7 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.8 KLO20325.1 - 8e-07 28.7 0.1 7.2e-06 25.6 0.1 2.2 1 1 0 1 1 1 1 Peptidase C26 zf-LYAR PF08790.6 KLO20327.1 - 2.2e-13 49.6 0.4 4e-13 48.8 0.2 1.5 1 0 0 1 1 1 1 LYAR-type C2HC zinc finger FtsH_ext PF06480.10 KLO20328.1 - 0.091 12.9 0.3 0.18 11.9 0.2 1.5 1 0 0 1 1 1 0 FtsH Extracellular Autophagy_N PF03986.8 KLO20329.1 - 4.8e-45 152.9 1.1 6.4e-45 152.4 0.0 1.8 2 0 0 2 2 2 1 Autophagocytosis associated protein (Atg3), N-terminal domain Autophagy_act_C PF03987.10 KLO20329.1 - 3.3e-22 78.4 0.2 6.3e-22 77.5 0.1 1.5 1 0 0 1 1 1 1 Autophagocytosis associated protein, active-site domain Autophagy_Cterm PF10381.4 KLO20329.1 - 7.5e-12 44.1 2.7 1.5e-11 43.2 1.9 1.5 1 0 0 1 1 1 1 Autophagocytosis associated protein C-terminal SNARE_assoc PF09335.6 KLO20331.1 - 0.0057 16.8 0.0 0.0058 16.8 0.0 1.0 1 0 0 1 1 1 1 SNARE associated Golgi protein Fungal_trans PF04082.13 KLO20332.1 - 8.9e-13 47.7 0.2 1.6e-12 46.8 0.2 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 KLO20332.1 - 3.5e-05 23.6 9.6 7.8e-05 22.5 6.6 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Glyco_hydro_63 PF03200.11 KLO20333.1 - 2e-06 26.0 5.6 7.3e-05 20.8 1.5 3.3 2 1 0 2 2 2 2 Mannosyl oligosaccharide glucosidase CEP44 PF15007.1 KLO20333.1 - 0.24 11.1 0.0 0.45 10.2 0.0 1.3 1 0 0 1 1 1 0 Centrosomal spindle body, CEP44 adh_short PF00106.20 KLO20334.1 - 1.4e-19 70.6 0.2 1.9e-19 70.1 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 KLO20334.1 - 6.8e-08 32.3 0.1 1.2e-07 31.5 0.0 1.4 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 KLO20334.1 - 0.00025 20.9 0.0 0.0004 20.2 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_7 PF13241.1 KLO20334.1 - 0.0011 19.1 0.0 0.0025 18.0 0.0 1.6 1 1 0 1 1 1 1 Putative NAD(P)-binding NAD_binding_10 PF13460.1 KLO20334.1 - 0.0015 18.6 0.3 0.0026 17.7 0.2 1.5 1 1 0 1 1 1 1 NADH(P)-binding THF_DHG_CYH_C PF02882.14 KLO20334.1 - 0.0035 16.4 0.0 0.0075 15.3 0.0 1.5 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain 3HCDH_N PF02737.13 KLO20334.1 - 0.0071 16.0 0.2 0.013 15.1 0.1 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ADH_zinc_N PF00107.21 KLO20334.1 - 0.011 15.2 0.0 0.03 13.8 0.0 1.8 1 1 0 1 1 1 0 Zinc-binding dehydrogenase F420_oxidored PF03807.12 KLO20334.1 - 0.034 14.5 0.2 0.1 13.0 0.1 1.9 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent Helicase_RecD PF05127.9 KLO20334.1 - 0.069 12.7 0.1 0.16 11.6 0.1 1.5 1 0 0 1 1 1 0 Helicase FAD_binding_3 PF01494.14 KLO20334.1 - 0.11 11.5 0.2 0.29 10.1 0.2 1.6 2 0 0 2 2 2 0 FAD binding domain Shikimate_DH PF01488.15 KLO20334.1 - 0.12 12.4 0.0 0.23 11.5 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase PX PF00787.19 KLO20336.1 - 1.2e-15 57.2 0.0 1.9e-15 56.6 0.0 1.3 1 0 0 1 1 1 1 PX domain Smr PF01713.16 KLO20337.1 - 7.6e-13 48.4 1.2 2.1e-12 47.0 0.1 2.4 3 0 0 3 3 3 1 Smr domain RCC1 PF00415.13 KLO20338.1 - 5.3e-63 209.0 0.2 9.4e-10 38.5 0.0 8.2 7 1 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 KLO20338.1 - 5.8e-37 124.5 42.1 4e-09 35.8 0.1 7.5 8 0 0 8 8 8 6 Regulator of chromosome condensation (RCC1) repeat CBM_X PF06204.6 KLO20338.1 - 0.001 18.5 0.3 0.22 11.0 0.1 3.5 3 1 0 3 3 3 1 Putative carbohydrate binding domain DUF2986 PF11661.3 KLO20339.1 - 0.23 11.8 0.4 0.55 10.5 0.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2986) DUF4614 PF15391.1 KLO20340.1 - 0.96 9.1 10.5 0.11 12.3 3.0 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4614) Glyco_hydro_92 PF07971.7 KLO20341.1 - 2.1e-122 409.3 0.7 2.6e-122 409.0 0.5 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 Pept_tRNA_hydro PF01195.14 KLO20342.1 - 1.4e-29 102.8 0.0 1.8e-29 102.5 0.0 1.1 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase DPM3 PF08285.6 KLO20343.1 - 6e-31 106.1 0.1 6.6e-31 106.0 0.1 1.0 1 0 0 1 1 1 1 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) HlyIII PF03006.15 KLO20344.1 - 8.4e-35 120.1 19.8 1.3e-34 119.6 13.7 1.3 1 0 0 1 1 1 1 Haemolysin-III related DUF1691 PF07950.6 KLO20344.1 - 0.00029 20.7 0.6 0.00069 19.5 0.4 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF1691) Rubredoxin PF00301.15 KLO20345.1 - 0.074 12.9 0.0 0.15 11.9 0.0 1.4 1 0 0 1 1 1 0 Rubredoxin Nudc_N PF14050.1 KLO20347.1 - 0.002 18.0 0.0 0.0035 17.2 0.0 1.4 1 0 0 1 1 1 1 N-terminal conserved domain of Nudc. FAM212 PF15342.1 KLO20347.1 - 0.027 14.0 0.1 0.072 12.7 0.1 1.7 1 0 0 1 1 1 0 FAM212 family Ribosomal_L32p PF01783.18 KLO20348.1 - 0.16 12.1 0.3 0.52 10.5 0.0 2.0 2 0 0 2 2 2 0 Ribosomal L32p protein family Nudc_N PF14050.1 KLO20349.1 - 0.14 12.1 0.0 0.25 11.3 0.0 1.4 1 0 0 1 1 1 0 N-terminal conserved domain of Nudc. Ribosomal_S8e PF01201.17 KLO20350.1 - 7.6e-52 174.9 0.8 9.7e-52 174.6 0.6 1.1 1 0 0 1 1 1 1 Ribosomal protein S8e Glyco_transf_90 PF05686.7 KLO20351.1 - 2.2e-19 69.4 0.2 2.2e-19 69.4 0.1 2.0 3 0 0 3 3 3 1 Glycosyl transferase family 90 dCMP_cyt_deam_1 PF00383.17 KLO20352.1 - 2.2e-19 69.0 1.7 2.8e-19 68.6 1.1 1.1 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region dCMP_cyt_deam_2 PF08211.6 KLO20352.1 - 2.5e-11 43.6 2.5 1.4e-10 41.2 0.3 2.1 2 0 0 2 2 2 1 Cytidine and deoxycytidylate deaminase zinc-binding region LmjF365940-deam PF14421.1 KLO20352.1 - 0.029 13.7 4.6 0.038 13.3 0.2 2.1 1 1 1 2 2 2 0 A distinct subfamily of CDD/CDA-like deaminases XOO_2897-deam PF14440.1 KLO20352.1 - 0.071 12.8 0.1 0.09 12.4 0.1 1.1 1 0 0 1 1 1 0 Xanthomonas XOO_2897-like deaminase UDPGP PF01704.13 KLO20353.1 - 2.6e-180 599.4 1.9 3e-180 599.2 1.3 1.0 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase Metallophos PF00149.23 KLO20354.1 - 1e-14 54.4 0.0 1.5e-14 53.8 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 KLO20354.1 - 0.0087 15.9 0.0 0.012 15.4 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain BSD PF03909.12 KLO20355.1 - 7.3e-09 35.2 0.6 2.5e-08 33.5 0.2 2.1 1 1 0 1 1 1 1 BSD domain DUF883 PF05957.8 KLO20355.1 - 0.0092 16.3 0.3 0.15 12.4 0.0 2.5 2 0 0 2 2 2 1 Bacterial protein of unknown function (DUF883) DUF4407 PF14362.1 KLO20355.1 - 0.19 10.6 1.3 0.51 9.2 0.9 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Amidohydro_1 PF01979.15 KLO20356.1 - 7.1e-32 111.3 0.0 8.6e-32 111.0 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_5 PF13594.1 KLO20356.1 - 0.0084 15.9 0.0 0.098 12.4 0.0 2.3 2 0 0 2 2 2 1 Amidohydrolase Amidohydro_3 PF07969.6 KLO20356.1 - 0.02 14.1 0.5 0.75 8.9 0.0 2.6 2 2 0 2 2 2 0 Amidohydrolase family Amidohydro_4 PF13147.1 KLO20356.1 - 0.098 12.6 0.4 3.4 7.6 0.2 2.6 1 1 0 1 1 1 0 Amidohydrolase UDPGP PF01704.13 KLO20357.1 - 1.4e-180 600.3 0.2 1.6e-180 600.1 0.1 1.0 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase SET PF00856.23 KLO20358.1 - 8e-12 45.7 0.0 3.6e-11 43.6 0.0 1.9 1 1 0 1 1 1 1 SET domain adh_short_C2 PF13561.1 KLO20361.1 - 3.1e-23 82.7 0.0 3.1e-13 50.0 0.0 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 KLO20361.1 - 3.1e-22 79.2 0.1 1.9e-21 76.6 0.0 1.9 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 KLO20361.1 - 3.7e-09 36.5 0.0 1e-08 35.0 0.0 1.7 2 0 0 2 2 2 1 KR domain Methyltransf_25 PF13649.1 KLO20361.1 - 0.0052 17.1 0.0 0.0096 16.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KLO20361.1 - 0.076 13.6 0.0 0.14 12.7 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Cpn60_TCP1 PF00118.19 KLO20363.1 - 2.5e-146 488.1 0.0 3e-146 487.8 0.0 1.1 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family FKBP_C PF00254.23 KLO20364.1 - 7.2e-28 96.4 0.7 1.5e-27 95.4 0.0 1.8 2 0 0 2 2 2 1 FKBP-type peptidyl-prolyl cis-trans isomerase BUD22 PF09073.5 KLO20364.1 - 3.1 6.7 34.2 5.3 6.0 23.7 1.3 1 0 0 1 1 1 0 BUD22 ARPC4 PF05856.7 KLO20365.1 - 5.2e-74 247.2 4.5 5.7e-74 247.1 3.1 1.0 1 0 0 1 1 1 1 ARP2/3 complex 20 kDa subunit (ARPC4) DUF3942 PF13078.1 KLO20365.1 - 0.11 12.5 1.4 0.84 9.7 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3942) zf-MYND PF01753.13 KLO20366.1 - 4e-10 39.3 17.5 8.1e-10 38.4 12.1 1.6 1 0 0 1 1 1 1 MYND finger TPR_12 PF13424.1 KLO20366.1 - 1.3e-06 28.2 7.5 6.1e-06 26.0 2.8 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.1 KLO20366.1 - 1.9e-05 24.9 5.0 0.00036 20.7 0.4 2.4 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_10 PF13374.1 KLO20366.1 - 2.4e-05 24.1 6.9 0.00045 20.0 0.0 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_21 PF09976.4 KLO20366.1 - 0.00041 20.3 1.5 0.00041 20.3 1.1 1.8 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_11 PF13414.1 KLO20366.1 - 0.00067 19.2 1.1 0.0031 17.1 0.1 2.2 1 1 1 2 2 2 2 TPR repeat TPR_16 PF13432.1 KLO20366.1 - 0.00094 19.7 1.7 0.00094 19.7 1.2 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.23 KLO20366.1 - 0.0025 17.3 0.1 0.0077 15.8 0.1 1.9 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_14 PF13428.1 KLO20366.1 - 0.0031 17.9 8.6 0.013 16.0 0.5 3.3 1 1 2 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.12 KLO20366.1 - 0.013 15.3 0.2 0.013 15.3 0.1 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_17 PF13431.1 KLO20366.1 - 0.039 14.1 0.3 3 8.2 0.0 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_7 PF13176.1 KLO20366.1 - 0.044 13.6 3.9 0.49 10.3 0.0 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_4 PF07721.9 KLO20366.1 - 0.071 13.5 11.0 0.12 12.8 0.0 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat Apc3 PF12895.2 KLO20366.1 - 2.8 8.1 7.5 0.12 12.4 0.4 2.1 2 1 1 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 SNF2_N PF00176.18 KLO20367.1 - 2.7e-68 229.9 0.4 6.2e-68 228.7 0.0 1.8 2 0 0 2 2 2 1 SNF2 family N-terminal domain HIRAN PF08797.6 KLO20367.1 - 3.9e-21 74.9 0.0 8.8e-21 73.8 0.0 1.6 1 0 0 1 1 1 1 HIRAN domain zf-PARP PF00645.13 KLO20367.1 - 5.7e-15 55.3 0.0 1.5e-14 54.0 0.0 1.8 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region Helicase_C PF00271.26 KLO20367.1 - 1.1e-09 38.0 0.0 1.4e-08 34.4 0.0 2.5 1 1 0 1 1 1 1 Helicase conserved C-terminal domain zf-C3HC4 PF00097.20 KLO20367.1 - 2.3e-07 30.3 7.2 4.5e-07 29.4 5.0 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 KLO20367.1 - 1e-06 28.6 7.7 2e-06 27.7 5.3 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 KLO20367.1 - 1.7e-06 27.7 5.6 3.4e-06 26.7 3.9 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 KLO20367.1 - 1.8e-06 27.5 4.5 3.1e-06 26.7 3.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KLO20367.1 - 6.3e-06 25.8 4.1 1.2e-05 24.8 2.8 1.5 1 0 0 1 1 1 1 zinc-RING finger domain ResIII PF04851.10 KLO20367.1 - 2.6e-05 24.1 0.0 6.2e-05 22.9 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit zf-C3HC4_4 PF15227.1 KLO20367.1 - 0.00068 19.4 8.4 0.0014 18.4 5.8 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.2 KLO20367.1 - 0.0063 16.5 3.1 0.018 15.1 2.1 1.8 1 1 0 1 1 1 1 RING-H2 zinc finger zf-RING_6 PF14835.1 KLO20367.1 - 0.024 14.3 1.9 0.07 12.9 1.3 1.7 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-RING_UBOX PF13445.1 KLO20367.1 - 0.26 11.0 7.3 0.68 9.7 5.1 1.7 1 0 0 1 1 1 0 RING-type zinc-finger HMG_box PF00505.14 KLO20368.1 - 5.2e-13 49.0 2.6 5.2e-13 49.0 1.8 2.4 2 0 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.5 KLO20368.1 - 2.8e-05 24.4 1.1 2.8e-05 24.4 0.7 2.4 2 0 0 2 2 2 1 HMG-box domain MAT_Alpha1 PF04769.7 KLO20368.1 - 0.0044 16.3 0.1 0.0089 15.3 0.1 1.4 1 0 0 1 1 1 1 Mating-type protein MAT alpha 1 Ctr PF04145.10 KLO20369.1 - 2.3e-40 137.9 0.1 2.7e-40 137.7 0.1 1.1 1 0 0 1 1 1 1 Ctr copper transporter family DUF3421 PF11901.3 KLO20370.1 - 2.8e-21 75.4 0.1 2.9e-20 72.1 0.0 2.1 1 1 0 1 1 1 1 Protein of unknown function (DUF3421) IncA PF04156.9 KLO20370.1 - 0.0017 18.0 0.0 0.0025 17.4 0.0 1.2 1 0 0 1 1 1 1 IncA protein CBM_5_12 PF02839.9 KLO20370.1 - 0.0071 15.9 0.3 0.022 14.3 0.0 2.0 2 0 0 2 2 2 1 Carbohydrate binding domain RPA_interact_C PF14768.1 KLO20372.1 - 0.0058 17.0 0.2 0.01 16.2 0.1 1.4 1 0 0 1 1 1 1 Replication protein A interacting C-terminal MPC PF03650.8 KLO20374.1 - 1.2e-35 122.0 0.9 1.4e-35 121.7 0.6 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0041) Palm_thioest PF02089.10 KLO20375.1 - 1.3e-56 191.6 0.0 1.7e-56 191.2 0.0 1.1 1 0 0 1 1 1 1 Palmitoyl protein thioesterase Abhydrolase_1 PF00561.15 KLO20375.1 - 0.003 17.1 0.0 0.0043 16.6 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Sugar_tr PF00083.19 KLO20378.1 - 3.7e-92 309.2 22.6 4.4e-92 309.0 15.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 KLO20378.1 - 1.5e-19 69.9 24.3 1.5e-19 69.9 16.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Pkinase PF00069.20 KLO20379.1 - 1.2e-26 93.4 0.0 1.4e-26 93.1 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KLO20379.1 - 5.2e-23 81.4 0.0 5.7e-23 81.3 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KLO20379.1 - 1.6e-05 24.0 0.0 2.1e-05 23.6 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 KLO20379.1 - 0.00056 19.7 0.0 0.00062 19.5 0.0 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.17 KLO20379.1 - 0.024 13.9 0.0 0.034 13.5 0.0 1.2 1 0 0 1 1 1 0 RIO1 family Pox_ser-thr_kin PF05445.6 KLO20379.1 - 0.094 11.4 0.0 0.14 10.9 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase ALS_ss_C PF10369.4 KLO20380.1 - 2e-21 75.4 0.0 1.5e-19 69.4 0.0 2.3 2 0 0 2 2 2 2 Small subunit of acetolactate synthase ACT PF01842.20 KLO20380.1 - 7.4e-13 47.6 0.1 1.6e-12 46.5 0.0 1.6 1 0 0 1 1 1 1 ACT domain ACT_5 PF13710.1 KLO20380.1 - 4.8e-08 32.6 0.0 8.2e-08 31.9 0.0 1.4 1 0 0 1 1 1 1 ACT domain Pkinase PF00069.20 KLO20381.1 - 9.6e-60 201.9 0.0 1.2e-59 201.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KLO20381.1 - 2.3e-30 105.5 0.0 3.2e-30 105.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KLO20381.1 - 7.2e-10 38.2 0.0 1.2e-09 37.5 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 KLO20381.1 - 0.0037 17.0 0.5 0.013 15.2 0.1 1.9 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.9 KLO20381.1 - 0.032 13.3 0.0 0.058 12.4 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Fumarate_red_C PF02300.12 KLO20382.1 - 0.065 13.1 3.0 0.19 11.6 2.1 1.9 1 0 0 1 1 1 0 Fumarate reductase subunit C PDR_CDR PF06422.7 KLO20383.1 - 0.14 11.7 2.8 1.6 8.4 0.0 3.3 3 0 0 3 3 3 0 CDR ABC transporter UPF0182 PF03699.8 KLO20383.1 - 7.5 4.3 9.2 1.2 6.9 1.7 2.0 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0182) COG5 PF10392.4 KLO20384.1 - 3.5e-24 85.2 1.9 1.3e-23 83.4 1.3 2.0 1 0 0 1 1 1 1 Golgi transport complex subunit 5 DUF3759 PF12585.3 KLO20385.1 - 0.001 18.9 0.1 0.0018 18.1 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3759) WD40 PF00400.27 KLO20386.1 - 3.6e-19 67.8 2.4 0.00011 21.9 0.0 5.9 6 0 0 6 6 6 4 WD domain, G-beta repeat eIF2A PF08662.6 KLO20386.1 - 0.067 12.8 0.0 3.9 7.1 0.0 3.1 3 1 1 4 4 4 0 Eukaryotic translation initiation factor eIF2A DUF716 PF04819.7 KLO20387.1 - 1.2 8.5 6.3 3.7 6.9 4.4 1.9 1 1 0 1 1 1 0 Family of unknown function (DUF716) MFS_1 PF07690.11 KLO20388.1 - 4.7e-31 107.7 32.7 4.7e-31 107.7 22.7 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily Disulph_isomer PF06491.6 KLO20388.1 - 0.16 11.8 0.0 0.31 10.8 0.0 1.4 1 0 0 1 1 1 0 Disulphide isomerase FAD_binding_3 PF01494.14 KLO20389.1 - 1.8e-20 73.3 0.0 4e-20 72.1 0.0 1.5 1 1 0 1 1 1 1 FAD binding domain Amino_oxidase PF01593.19 KLO20389.1 - 0.00099 18.2 0.1 0.0094 15.0 0.0 2.0 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase DAO PF01266.19 KLO20389.1 - 0.0017 17.3 0.2 0.48 9.2 0.3 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 KLO20389.1 - 0.0065 16.4 0.6 0.015 15.3 0.4 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 KLO20389.1 - 0.018 14.8 0.0 0.53 10.0 0.0 2.2 2 0 0 2 2 2 0 FAD-NAD(P)-binding Pyr_redox PF00070.22 KLO20389.1 - 0.13 12.6 0.4 0.38 11.1 0.3 1.8 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase DOT1 PF08123.8 KLO20391.1 - 2.8e-59 199.8 0.0 3.9e-59 199.4 0.0 1.2 1 0 0 1 1 1 1 Histone methylation protein DOT1 Methyltransf_26 PF13659.1 KLO20391.1 - 0.00035 20.5 0.0 0.00067 19.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 KLO20391.1 - 0.0013 19.2 0.0 0.003 18.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KLO20391.1 - 0.025 14.1 0.0 0.045 13.3 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.7 KLO20391.1 - 0.041 14.3 0.0 0.08 13.4 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain NAD_binding_2 PF03446.10 KLO20392.1 - 2e-23 83.0 0.0 3.7e-23 82.1 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.1 KLO20392.1 - 9.1e-12 45.1 0.0 1.6e-11 44.2 0.0 1.3 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase Shikimate_DH PF01488.15 KLO20392.1 - 1.2e-05 25.4 0.0 2.2e-05 24.5 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase F420_oxidored PF03807.12 KLO20392.1 - 4.2e-05 23.8 0.0 0.00012 22.4 0.0 1.8 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Semialdhyde_dh PF01118.19 KLO20392.1 - 0.027 14.7 0.0 4.5 7.6 0.0 2.6 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain GFO_IDH_MocA PF01408.17 KLO20392.1 - 0.095 13.2 0.0 0.38 11.2 0.0 2.0 2 0 0 2 2 2 0 Oxidoreductase family, NAD-binding Rossmann fold Actin PF00022.14 KLO20393.1 - 2.5e-41 141.3 0.0 4e-20 71.6 0.0 2.1 2 0 0 2 2 2 2 Actin RED_C PF07807.6 KLO20393.1 - 0.0023 18.1 0.1 0.0023 18.1 0.0 3.3 3 1 1 4 4 4 1 RED-like protein C-terminal region CRT10 PF08728.5 KLO20393.1 - 1.2 7.0 5.8 0.2 9.6 1.1 1.6 1 1 1 2 2 2 0 CRT10 Ras PF00071.17 KLO20394.1 - 4.2e-63 211.5 0.0 5e-63 211.3 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KLO20394.1 - 2.3e-20 73.2 0.0 3.9e-20 72.5 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KLO20394.1 - 2.7e-13 49.5 0.0 3.3e-13 49.2 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 KLO20394.1 - 4e-06 26.1 0.0 4.7e-06 25.9 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 KLO20394.1 - 3.3e-05 23.3 0.1 8.2e-05 22.1 0.1 1.7 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 KLO20394.1 - 0.0002 21.3 0.0 0.0003 20.7 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 KLO20394.1 - 0.019 14.2 0.0 0.36 10.1 0.0 2.1 1 1 0 1 1 1 0 Ferrous iron transport protein B AAA_22 PF13401.1 KLO20394.1 - 0.022 14.8 0.0 0.075 13.1 0.0 2.0 1 1 1 2 2 2 0 AAA domain AAA_16 PF13191.1 KLO20394.1 - 0.026 14.4 0.1 0.048 13.6 0.1 1.8 1 1 0 1 1 1 0 AAA ATPase domain DUF258 PF03193.11 KLO20394.1 - 0.028 13.6 0.0 0.048 12.8 0.0 1.7 1 1 0 1 1 1 0 Protein of unknown function, DUF258 AAA_29 PF13555.1 KLO20394.1 - 0.028 13.9 0.0 0.087 12.3 0.0 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain G-alpha PF00503.15 KLO20394.1 - 0.031 12.9 0.1 4.7 5.7 0.0 2.7 2 1 0 2 2 2 0 G-protein alpha subunit SRPRB PF09439.5 KLO20394.1 - 0.039 13.1 0.0 0.063 12.5 0.0 1.3 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit MreB_Mbl PF06723.8 KLO20394.1 - 0.047 12.2 0.1 0.066 11.7 0.1 1.1 1 0 0 1 1 1 0 MreB/Mbl protein Septin PF00735.13 KLO20394.1 - 0.072 12.0 0.0 0.14 11.1 0.0 1.5 1 0 0 1 1 1 0 Septin NACHT PF05729.7 KLO20394.1 - 0.076 12.6 0.0 0.14 11.8 0.0 1.4 1 0 0 1 1 1 0 NACHT domain ABC_tran PF00005.22 KLO20394.1 - 0.1 12.9 0.0 0.16 12.2 0.0 1.6 1 1 0 1 1 1 0 ABC transporter AAA PF00004.24 KLO20394.1 - 0.1 12.8 0.0 0.37 11.0 0.0 1.8 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) UvrD_C PF13361.1 KLO20395.1 - 6.3e-14 52.1 0.0 4e-10 39.6 0.0 3.9 4 0 0 4 4 4 2 UvrD-like helicase C-terminal domain UvrD-helicase PF00580.16 KLO20395.1 - 1.9e-07 30.7 0.3 1.9e-07 30.7 0.2 3.7 4 0 0 4 4 4 1 UvrD/REP helicase N-terminal domain UvrD_C_2 PF13538.1 KLO20395.1 - 2.5e-06 27.5 0.7 8.2e-05 22.6 0.1 3.3 2 1 0 2 2 2 1 UvrD-like helicase C-terminal domain AAA_22 PF13401.1 KLO20395.1 - 0.00078 19.5 0.0 2.1 8.5 0.0 3.2 2 0 0 2 2 2 2 AAA domain TPR_2 PF07719.12 KLO20395.1 - 0.0099 15.7 12.8 0.34 10.9 0.0 4.8 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_11 PF13414.1 KLO20395.1 - 0.013 15.0 6.5 0.33 10.6 0.0 3.8 2 1 0 3 3 3 0 TPR repeat AAA_12 PF13087.1 KLO20395.1 - 0.015 14.6 0.0 0.055 12.8 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.1 KLO20395.1 - 0.019 14.5 0.0 1.2 8.7 0.0 2.6 2 0 0 2 2 2 0 AAA domain TPR_1 PF00515.23 KLO20395.1 - 0.028 14.0 7.0 4.5 7.0 0.0 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat ABC_tran PF00005.22 KLO20396.1 - 1.7e-26 93.1 0.0 8.2e-26 90.9 0.0 2.1 1 1 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 KLO20396.1 - 1.4e-12 48.2 2.1 5.4e-11 42.9 0.1 3.0 2 1 0 2 2 2 1 AAA domain AAA_15 PF13175.1 KLO20396.1 - 3.7e-07 29.5 0.0 0.011 14.8 0.0 2.4 2 0 0 2 2 2 2 AAA ATPase domain SMC_N PF02463.14 KLO20396.1 - 9.7e-07 28.2 0.0 0.025 13.7 0.0 2.3 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 KLO20396.1 - 0.0019 18.5 0.0 0.0048 17.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 KLO20396.1 - 0.0021 18.0 0.2 0.027 14.4 0.0 2.6 3 0 0 3 3 3 1 AAA ATPase domain AAA_29 PF13555.1 KLO20396.1 - 0.0044 16.5 0.0 0.0093 15.4 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_17 PF13207.1 KLO20396.1 - 0.0049 17.6 0.0 0.011 16.5 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.1 KLO20396.1 - 0.0061 16.4 0.0 0.074 12.9 0.0 2.8 3 0 0 3 3 3 1 AAA domain AAA_19 PF13245.1 KLO20396.1 - 0.0097 15.6 0.2 0.03 14.0 0.0 1.8 2 0 0 2 2 2 1 Part of AAA domain AAA_30 PF13604.1 KLO20396.1 - 0.013 15.0 0.0 0.025 14.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.1 KLO20396.1 - 0.013 15.6 0.0 0.092 12.8 0.0 2.4 2 0 0 2 2 2 0 AAA domain SbcCD_C PF13558.1 KLO20396.1 - 0.016 15.1 0.1 0.046 13.6 0.1 1.8 1 0 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_10 PF12846.2 KLO20396.1 - 0.051 12.9 0.5 0.12 11.7 0.1 1.8 2 0 0 2 2 2 0 AAA-like domain DUF258 PF03193.11 KLO20396.1 - 0.1 11.7 0.0 0.19 10.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_18 PF13238.1 KLO20396.1 - 0.13 12.5 0.2 0.45 10.8 0.0 1.9 2 0 0 2 2 2 0 AAA domain Nic96 PF04097.9 KLO20397.1 - 3.8e-133 444.7 0.0 5.3e-133 444.3 0.0 1.1 1 0 0 1 1 1 1 Nup93/Nic96 APH PF01636.18 KLO20397.1 - 0.021 14.5 0.3 0.021 14.5 0.2 2.7 3 0 0 3 3 3 0 Phosphotransferase enzyme family TPR_4 PF07721.9 KLO20397.1 - 0.11 12.9 8.7 21 5.9 1.8 4.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.12 KLO20397.1 - 0.76 9.8 4.0 41 4.4 0.2 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat Cullin PF00888.17 KLO20398.1 - 0.0014 17.3 0.0 0.0018 16.9 0.0 1.1 1 0 0 1 1 1 1 Cullin family Mpv17_PMP22 PF04117.7 KLO20399.1 - 1.4e-23 82.3 0.3 2e-23 81.7 0.2 1.2 1 0 0 1 1 1 1 Mpv17 / PMP22 family Vfa1 PF08432.5 KLO20400.1 - 1.6 8.7 11.7 0.83 9.6 6.2 2.1 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 Sec63 PF02889.11 KLO20402.1 - 1.1e-25 90.4 0.0 1.9e-25 89.7 0.0 1.3 1 0 0 1 1 1 1 Sec63 Brl domain DnaJ PF00226.26 KLO20402.1 - 1.6e-14 53.3 0.1 5.1e-14 51.7 0.1 1.9 1 0 0 1 1 1 1 DnaJ domain HAUS4 PF14735.1 KLO20402.1 - 0.048 12.9 0.2 7.9 5.7 0.0 2.3 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 4 PUF PF00806.14 KLO20403.1 - 5.4e-56 183.0 14.1 1.2e-07 30.7 0.1 8.6 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat DUF260 PF03195.9 KLO20403.1 - 0.02 15.1 0.3 0.64 10.3 0.0 3.4 2 2 1 3 3 3 0 Protein of unknown function DUF260 DUF3556 PF12077.3 KLO20403.1 - 0.31 9.0 0.5 0.47 8.4 0.3 1.1 1 0 0 1 1 1 0 Transmembrane protein of unknown function (DUF3556) Atg14 PF10186.4 KLO20404.1 - 2.6e-18 66.0 0.1 5e-18 65.0 0.1 1.4 1 0 0 1 1 1 1 UV radiation resistance protein and autophagy-related subunit 14 ExoD PF06055.7 KLO20404.1 - 0.00056 19.0 0.5 0.0011 18.1 0.4 1.3 1 0 0 1 1 1 1 Exopolysaccharide synthesis, ExoD APG6 PF04111.7 KLO20404.1 - 0.0064 15.5 2.1 0.14 11.1 0.0 2.1 2 0 0 2 2 2 1 Autophagy protein Apg6 Spectrin PF00435.16 KLO20404.1 - 0.045 14.0 3.0 0.089 13.0 2.1 1.5 1 0 0 1 1 1 0 Spectrin repeat Med2 PF11214.3 KLO20405.1 - 0.00019 21.4 0.9 0.00032 20.6 0.6 1.3 1 0 0 1 1 1 1 Mediator complex subunit 2 Sipho_Gp37 PF14594.1 KLO20405.1 - 0.12 11.5 0.1 0.18 11.0 0.1 1.2 1 0 0 1 1 1 0 Siphovirus ReqiPepy6 Gp37-like protein SprT-like PF10263.4 KLO20406.1 - 1.2e-39 135.5 1.3 1.8e-39 134.9 0.9 1.3 1 0 0 1 1 1 1 SprT-like family p450 PF00067.17 KLO20407.1 - 1.5e-58 198.4 0.0 4.4e-58 196.9 0.0 1.6 1 1 0 1 1 1 1 Cytochrome P450 Acatn PF13000.2 KLO20408.1 - 2.7e-135 452.0 24.7 1.9e-65 221.4 10.0 3.4 1 1 2 3 3 3 3 Acetyl-coenzyme A transporter 1 GSH-S_ATP PF02955.11 KLO20409.1 - 0.1 11.7 0.0 0.11 11.6 0.0 1.2 1 0 0 1 1 1 0 Prokaryotic glutathione synthetase, ATP-grasp domain Rhodanese PF00581.15 KLO20410.1 - 1.1e-17 64.3 0.0 4.7e-10 39.8 0.0 2.4 2 0 0 2 2 2 2 Rhodanese-like domain V-ATPase_C PF03223.10 KLO20411.1 - 1.6e-111 372.8 1.2 1.8e-111 372.6 0.8 1.0 1 0 0 1 1 1 1 V-ATPase subunit C KH_1 PF00013.24 KLO20412.1 - 3.4e-39 132.3 2.8 1.4e-08 34.2 0.0 7.2 7 0 0 7 7 7 4 KH domain KH_3 PF13014.1 KLO20412.1 - 1e-27 95.2 3.3 2.7e-06 26.8 0.0 6.7 7 0 0 7 7 7 4 KH domain HATPase_c_5 PF14501.1 KLO20412.1 - 0.043 13.5 0.1 0.11 12.2 0.1 1.7 1 0 0 1 1 1 0 GHKL domain IBR PF01485.16 KLO20413.1 - 2.4e-16 59.3 41.2 1.9e-11 43.6 3.4 4.3 3 1 1 4 4 4 2 IBR domain RWD PF05773.17 KLO20413.1 - 1.9e-11 43.8 0.0 3.8e-11 42.8 0.0 1.5 1 0 0 1 1 1 1 RWD domain zf-RING_2 PF13639.1 KLO20413.1 - 2.7e-06 27.0 10.0 2.7e-06 27.0 6.9 4.7 3 2 1 4 4 4 1 Ring finger domain zf-C3HC4_2 PF13923.1 KLO20413.1 - 4.2e-05 23.4 9.6 4.2e-05 23.4 6.6 4.9 3 2 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 KLO20413.1 - 6.9e-05 22.5 11.8 6.9e-05 22.5 8.2 4.5 3 3 1 4 4 4 1 zinc-RING finger domain zf-C3HC4 PF00097.20 KLO20413.1 - 0.00083 18.9 8.6 0.00083 18.9 6.0 4.7 4 1 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 KLO20413.1 - 0.015 14.9 7.7 0.015 14.9 5.3 2.6 2 0 0 2 2 2 0 RING-type zinc-finger Urb2 PF10441.4 KLO20414.1 - 3.5e-36 124.8 0.0 5.1e-35 121.1 0.0 2.5 2 0 0 2 2 2 1 Urb2/Npa2 family DUF3628 PF12300.3 KLO20414.1 - 0.068 13.1 0.3 0.12 12.4 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3628) TRAPP PF04051.11 KLO20415.1 - 5.9e-35 120.0 0.0 7.1e-35 119.7 0.0 1.1 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component DHO_dh PF01180.16 KLO20416.1 - 3.1e-14 52.6 0.0 5.3e-14 51.8 0.0 1.3 1 1 0 1 1 1 1 Dihydroorotate dehydrogenase HMG_box PF00505.14 KLO20417.1 - 3.8e-13 49.5 0.1 7.1e-13 48.6 0.1 1.5 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 KLO20417.1 - 0.00058 20.1 0.0 0.001 19.4 0.0 1.4 1 0 0 1 1 1 1 HMG-box domain PARP PF00644.15 KLO20418.1 - 2.2e-59 200.3 0.0 5.6e-59 199.0 0.0 1.7 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain PARP_reg PF02877.9 KLO20418.1 - 1.5e-37 128.2 0.0 2.7e-37 127.4 0.0 1.4 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase, regulatory domain WGR PF05406.10 KLO20418.1 - 4e-22 77.9 0.7 1.8e-21 75.8 0.2 2.2 2 0 0 2 2 2 1 WGR domain Prp19_bind PF06991.6 KLO20419.1 - 3.7e-64 216.6 35.7 3.7e-64 216.6 24.7 2.8 2 1 1 3 3 3 1 Splicing factor, Prp19-binding domain zf-CCHC PF00098.18 KLO20419.1 - 0.3 11.0 2.0 0.85 9.6 1.4 1.8 1 1 0 1 1 1 0 Zinc knuckle UMP1 PF05348.6 KLO20420.1 - 1.4e-17 63.8 0.8 2.3e-17 63.1 0.6 1.4 1 1 0 1 1 1 1 Proteasome maturation factor UMP1 NAD_binding_8 PF13450.1 KLO20421.1 - 7.2e-14 51.5 0.0 1.7e-13 50.3 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 KLO20421.1 - 5e-05 23.1 0.0 0.0003 20.5 0.0 2.2 2 0 0 2 2 2 1 FAD-NAD(P)-binding FAD_binding_2 PF00890.19 KLO20421.1 - 0.0038 16.1 0.0 0.0053 15.6 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 KLO20421.1 - 0.004 17.0 0.0 0.015 15.2 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 KLO20421.1 - 0.0064 15.4 0.0 0.012 14.5 0.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.12 KLO20421.1 - 0.0078 15.3 0.1 0.023 13.7 0.0 1.7 2 0 0 2 2 2 1 Thi4 family Pyr_redox_3 PF13738.1 KLO20421.1 - 0.011 15.8 0.0 1.3 9.0 0.0 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.19 KLO20421.1 - 0.012 14.7 0.0 1.6 7.7 0.0 3.0 3 0 0 3 3 3 0 Flavin containing amine oxidoreductase FAD_binding_3 PF01494.14 KLO20421.1 - 0.092 11.7 0.0 0.14 11.1 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain DHFR_2 PF06442.6 KLO20423.1 - 0.096 12.3 0.1 0.96 9.1 0.0 2.2 2 0 0 2 2 2 0 R67 dihydrofolate reductase zf-MYND PF01753.13 KLO20425.1 - 0.024 14.5 4.3 0.05 13.4 3.0 1.5 1 0 0 1 1 1 0 MYND finger DHquinase_I PF01487.10 KLO20425.1 - 0.04 13.5 0.0 0.11 12.1 0.0 1.6 2 0 0 2 2 2 0 Type I 3-dehydroquinase Myb_DNA-binding PF00249.26 KLO20426.1 - 1.9e-38 130.2 7.4 1.4e-13 50.6 0.0 4.6 4 0 0 4 4 4 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 KLO20426.1 - 3e-36 123.3 5.7 6e-15 55.0 0.0 3.5 1 1 2 3 3 3 3 Myb-like DNA-binding domain OAF PF14941.1 KLO20426.1 - 0.014 14.5 0.2 0.038 13.1 0.1 1.6 2 0 0 2 2 2 0 Transcriptional regulator, Out at first Rap1_C PF11626.3 KLO20426.1 - 0.018 14.9 4.1 12 5.9 0.1 3.4 1 1 0 2 2 2 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain zf-C2H2_4 PF13894.1 KLO20426.1 - 1.4 9.4 8.1 7.3 7.1 0.9 3.8 3 0 0 3 3 3 0 C2H2-type zinc finger Baculo_PEP_C PF04513.7 KLO20427.1 - 2.1 8.1 4.7 2.5 7.9 2.5 1.6 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Spc7 PF08317.6 KLO20428.1 - 6.1e-54 182.8 11.2 1e-53 182.1 7.7 1.2 1 0 0 1 1 1 1 Spc7 kinetochore protein DUF4315 PF14193.1 KLO20428.1 - 0.0027 17.5 4.9 0.12 12.3 2.2 3.7 3 1 1 4 4 4 1 Domain of unknown function (DUF4315) Spc7_C2 PF15577.1 KLO20428.1 - 0.015 14.9 0.1 0.036 13.7 0.1 1.6 1 0 0 1 1 1 0 Spc7_C2 Phage_GPO PF05929.6 KLO20428.1 - 0.19 10.9 4.5 0.37 10.0 3.1 1.4 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase BTB PF00651.26 KLO20430.1 - 0.016 15.1 0.0 0.074 13.0 0.0 1.9 2 0 0 2 2 2 0 BTB/POZ domain DNA_pol_B_thumb PF14791.1 KLO20430.1 - 0.092 12.4 0.0 0.18 11.5 0.0 1.5 1 0 0 1 1 1 0 DNA polymerase beta thumb Kinesin PF00225.18 KLO20433.1 - 3.8e-85 285.5 0.0 2.2e-84 283.0 0.0 2.2 1 1 0 1 1 1 1 Kinesin motor domain Beta_elim_lyase PF01212.16 KLO20434.1 - 1e-68 231.6 0.0 1.4e-68 231.1 0.0 1.1 1 0 0 1 1 1 1 Beta-eliminating lyase zf-met2 PF12907.2 KLO20435.1 - 8.3e-12 44.8 0.5 1.1e-11 44.5 0.4 1.2 1 0 0 1 1 1 1 Zinc-binding 4F5 PF04419.9 KLO20435.1 - 1e-05 26.1 8.9 1e-05 26.1 6.1 1.7 2 0 0 2 2 2 1 4F5 protein family zf-C2H2_6 PF13912.1 KLO20435.1 - 0.14 12.1 1.1 0.29 11.1 0.7 1.6 1 1 0 1 1 1 0 C2H2-type zinc finger zf-Tim10_DDP PF02953.10 KLO20436.1 - 4e-23 80.4 0.3 4.6e-23 80.2 0.2 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger WD40 PF00400.27 KLO20437.1 - 3.1e-11 42.7 26.8 0.0032 17.3 0.2 8.9 10 0 0 10 10 10 5 WD domain, G-beta repeat CobT PF06213.7 KLO20437.1 - 0.0063 15.6 1.4 0.011 14.8 1.0 1.3 1 0 0 1 1 1 1 Cobalamin biosynthesis protein CobT Nucleoporin_N PF08801.6 KLO20437.1 - 0.11 11.1 6.1 13 4.3 0.0 4.3 2 1 1 3 3 3 0 Nup133 N terminal like Nop14 PF04147.7 KLO20437.1 - 2.4 5.9 4.4 3.5 5.4 3.0 1.1 1 0 0 1 1 1 0 Nop14-like family Ion_trans_2 PF07885.11 KLO20439.1 - 2.7e-25 87.8 31.3 2.8e-13 49.3 6.1 2.9 3 0 0 3 3 3 2 Ion channel Flavi_NS4A PF01350.12 KLO20439.1 - 0.18 11.3 1.8 0.48 9.9 1.3 1.7 1 0 0 1 1 1 0 Flavivirus non-structural protein NS4A SUR7 PF06687.7 KLO20439.1 - 0.28 10.7 7.4 6.3 6.3 2.3 2.6 2 0 0 2 2 2 0 SUR7/PalI family Lig_chan PF00060.21 KLO20439.1 - 0.29 10.8 4.4 2.5 7.8 0.1 2.8 1 1 1 2 2 2 0 Ligand-gated ion channel Ctr PF04145.10 KLO20439.1 - 5 7.1 8.2 8.8 6.3 0.1 3.6 2 1 1 3 3 3 0 Ctr copper transporter family Ribosomal_S14 PF00253.16 KLO20440.1 - 4.2e-17 61.2 3.5 4.5e-17 61.1 2.4 1.0 1 0 0 1 1 1 1 Ribosomal protein S14p/S29e DUF1451 PF07295.6 KLO20440.1 - 0.028 14.2 0.2 0.028 14.1 0.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1451) ZZ PF00569.12 KLO20440.1 - 0.3 10.6 3.8 0.52 9.9 0.2 2.1 1 1 1 2 2 2 0 Zinc finger, ZZ type OPT PF03169.10 KLO20441.1 - 2.3e-192 640.7 60.0 2.6e-192 640.5 41.6 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein TauD PF02668.11 KLO20442.1 - 9.7e-51 172.8 0.2 1.2e-50 172.5 0.1 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Prp19 PF08606.6 KLO20443.1 - 2.3e-31 107.3 2.5 5.6e-31 106.0 1.7 1.7 1 0 0 1 1 1 1 Prp19/Pso4-like WD40 PF00400.27 KLO20443.1 - 8.6e-14 50.7 0.4 2.3e-05 24.0 0.0 5.6 5 0 0 5 5 5 2 WD domain, G-beta repeat zf-Nse PF11789.3 KLO20443.1 - 0.0011 18.4 0.0 0.002 17.5 0.0 1.4 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit DUF3312 PF11768.3 KLO20443.1 - 0.024 12.8 0.0 0.036 12.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3312) DUF3166 PF11365.3 KLO20443.1 - 0.06 13.7 0.1 0.2 12.1 0.0 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF3166) EH_Signature PF15611.1 KLO20443.1 - 0.1 11.6 0.0 0.15 11.1 0.0 1.1 1 0 0 1 1 1 0 EH_Signature domain TPR_11 PF13414.1 KLO20444.1 - 3.7e-20 71.3 3.9 4.8e-18 64.5 2.0 1.9 1 1 1 2 2 2 2 TPR repeat TPR_1 PF00515.23 KLO20444.1 - 6e-14 50.9 1.2 2.5e-06 26.8 0.3 3.6 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.12 KLO20444.1 - 4.1e-09 35.6 0.2 0.00035 20.2 0.1 3.3 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_17 PF13431.1 KLO20444.1 - 2e-08 33.8 0.1 0.00051 20.0 0.2 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.1 KLO20444.1 - 1.6e-05 25.4 0.3 3.2e-05 24.4 0.1 1.5 1 1 0 1 1 1 1 Tetratricopeptide repeat TPR_12 PF13424.1 KLO20444.1 - 6.9e-05 22.7 1.2 0.0029 17.5 0.2 2.0 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.1 KLO20444.1 - 0.0048 16.5 0.6 0.76 9.7 0.1 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.1 KLO20444.1 - 0.026 15.1 0.1 0.12 13.0 0.0 2.0 1 1 1 2 2 2 0 Tetratricopeptide repeat Apc3 PF12895.2 KLO20444.1 - 0.077 13.1 0.6 0.13 12.4 0.4 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.1 KLO20444.1 - 0.081 12.7 0.0 1.8 8.5 0.0 3.1 4 0 0 4 4 4 0 Tetratricopeptide repeat MIT PF04212.13 KLO20444.1 - 4.7 7.1 5.9 4 7.3 2.0 2.2 1 1 1 2 2 2 0 MIT (microtubule interacting and transport) domain HRDC PF00570.18 KLO20445.1 - 0.04 13.6 1.4 4 7.2 0.0 2.1 1 1 1 2 2 2 0 HRDC domain DUF3285 PF11688.3 KLO20445.1 - 0.078 12.6 0.0 0.078 12.6 0.0 1.8 2 1 0 2 2 2 0 Protein of unknown function (DUF3285) C2 PF00168.25 KLO20446.1 - 5.9e-79 259.9 5.5 3.1e-17 62.1 0.0 5.5 5 0 0 5 5 5 5 C2 domain GST_N PF02798.15 KLO20447.1 - 4.6e-06 26.7 0.0 8.2e-06 25.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 KLO20447.1 - 1.6e-05 25.0 0.0 2.7e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 KLO20447.1 - 0.0021 18.0 0.0 0.02 14.9 0.0 2.2 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain Mito_carr PF00153.22 KLO20448.1 - 1.7e-17 62.9 0.2 0.0017 17.9 0.0 5.1 5 0 0 5 5 5 4 Mitochondrial carrier protein RVT_thumb PF06817.9 KLO20449.1 - 0.034 13.7 0.0 0.06 12.9 0.0 1.5 1 0 0 1 1 1 0 Reverse transcriptase thumb domain RVT_3 PF13456.1 KLO20451.1 - 0.0019 17.9 0.0 0.0031 17.2 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase-like Aminotran_5 PF00266.14 KLO20452.1 - 1.2e-40 139.4 0.0 2.5e-40 138.3 0.0 1.5 1 1 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.15 KLO20452.1 - 0.1 10.8 0.1 0.33 9.1 0.0 1.8 2 0 0 2 2 2 0 Cys/Met metabolism PLP-dependent enzyme DUF1652 PF07865.6 KLO20452.1 - 0.16 11.5 0.2 3.6 7.2 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1652) DUF3529 PF12046.3 KLO20454.1 - 0.0081 15.2 1.0 0.39 9.7 0.0 2.8 2 1 1 3 3 3 2 Protein of unknown function (DUF3529) QCR10 PF09796.4 KLO20454.1 - 0.9 9.2 11.2 7 6.3 0.0 5.2 3 2 4 7 7 7 0 Ubiquinol-cytochrome-c reductase complex subunit (QCR10) WD40 PF00400.27 KLO20456.1 - 7.3e-42 139.7 13.7 1.2e-09 37.6 0.3 7.3 7 0 0 7 7 7 6 WD domain, G-beta repeat PQQ_2 PF13360.1 KLO20456.1 - 0.0054 16.2 0.0 0.34 10.3 0.0 2.5 2 1 0 2 2 2 1 PQQ-like domain Raftlin PF15250.1 KLO20456.1 - 0.067 11.7 0.4 0.096 11.1 0.3 1.1 1 0 0 1 1 1 0 Raftlin Nup160 PF11715.3 KLO20456.1 - 0.12 10.4 0.6 3.9 5.4 0.0 2.7 1 1 0 2 2 2 0 Nucleoporin Nup120/160 zf-HC5HC2H_2 PF13832.1 KLO20457.1 - 1.1e-33 115.5 13.9 8.8e-33 112.5 6.0 3.2 3 0 0 3 3 3 1 PHD-zinc-finger like domain zf-HC5HC2H PF13771.1 KLO20457.1 - 5.6e-25 87.3 6.2 5.6e-25 87.3 4.3 3.0 2 1 0 2 2 2 1 PHD-like zinc-binding domain EPL1 PF10513.4 KLO20457.1 - 2.1e-23 83.3 1.5 2.1e-23 83.3 1.1 2.4 2 0 0 2 2 2 1 Enhancer of polycomb-like Bromodomain PF00439.20 KLO20457.1 - 6.9e-19 67.5 0.3 1.5e-18 66.4 0.2 1.6 1 0 0 1 1 1 1 Bromodomain PHD_2 PF13831.1 KLO20457.1 - 9.3e-15 53.6 3.1 9.3e-15 53.6 2.2 3.0 3 0 0 3 3 3 2 PHD-finger PWWP PF00855.12 KLO20457.1 - 2.9e-14 53.0 0.4 9.5e-14 51.3 0.3 1.9 1 0 0 1 1 1 1 PWWP domain PHD PF00628.24 KLO20457.1 - 8.5e-10 38.1 5.6 8.5e-10 38.1 3.9 3.2 4 0 0 4 4 3 1 PHD-finger zf-PHD-like PF15446.1 KLO20457.1 - 0.0048 16.2 0.9 0.0048 16.2 0.6 2.3 2 0 0 2 2 2 1 PHD/FYVE-zinc-finger like domain C1_1 PF00130.17 KLO20457.1 - 0.013 15.2 0.2 0.013 15.2 0.2 3.0 3 0 0 3 3 3 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-RanBP PF00641.13 KLO20457.1 - 9.1 5.4 9.9 0.87 8.7 0.5 3.3 3 0 0 3 3 3 0 Zn-finger in Ran binding protein and others Prok-RING_1 PF14446.1 KLO20457.1 - 9.8 5.9 14.8 0.28 10.9 1.3 2.5 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 NUDIX PF00293.23 KLO20458.1 - 1.5e-10 40.8 0.0 3.1e-10 39.8 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain DUF3112 PF11309.3 KLO20459.1 - 0.81 9.4 10.5 0.084 12.6 2.0 2.3 1 1 0 2 2 2 0 Protein of unknown function (DUF3112) MCM PF00493.18 KLO20460.1 - 3e-142 473.2 0.2 3.8e-142 472.9 0.1 1.1 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 KLO20460.1 - 6e-18 65.4 0.1 2.7e-17 63.4 0.0 2.0 2 0 0 2 2 2 1 MCM N-terminal domain Mg_chelatase PF01078.16 KLO20460.1 - 8.9e-07 28.2 0.0 0.00027 20.1 0.0 2.4 1 1 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 KLO20460.1 - 0.00012 21.8 0.0 0.00029 20.5 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 KLO20460.1 - 0.0014 18.2 0.2 0.0063 16.1 0.1 2.2 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Mg_chelatase_2 PF13335.1 KLO20460.1 - 0.0063 16.8 0.9 0.027 14.8 0.2 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA PF00004.24 KLO20460.1 - 0.028 14.6 0.2 0.085 13.0 0.0 1.9 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) MitMem_reg PF13012.1 KLO20461.1 - 2.9e-19 69.2 0.0 4.3e-19 68.6 0.0 1.3 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function JAB PF01398.16 KLO20461.1 - 1e-13 51.0 0.0 1.1e-12 47.7 0.0 2.1 2 0 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease DUF4149 PF13664.1 KLO20462.1 - 5.1e-23 81.0 3.4 5.1e-23 81.0 2.4 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF4149) DUF2628 PF10947.3 KLO20462.1 - 0.065 13.0 0.1 0.065 13.0 0.1 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF2628) DUF2306 PF10067.4 KLO20462.1 - 0.4 10.8 4.8 1.2 9.3 0.1 2.5 2 1 0 2 2 2 0 Predicted membrane protein (DUF2306) LRR_9 PF14580.1 KLO20463.1 - 7.4e-56 188.4 0.0 1e-55 187.9 0.0 1.2 1 0 0 1 1 1 1 Leucine-rich repeat LRR_4 PF12799.2 KLO20463.1 - 1.3e-13 50.2 7.7 1.7e-07 30.6 1.8 3.7 3 1 0 4 4 4 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KLO20463.1 - 4.9e-11 42.2 8.9 1.3e-06 28.0 2.3 2.9 2 1 2 4 4 4 3 Leucine rich repeat LRR_1 PF00560.28 KLO20463.1 - 5.7e-05 22.6 4.0 1.5 9.1 0.3 4.7 5 1 0 5 5 5 2 Leucine Rich Repeat LRR_7 PF13504.1 KLO20463.1 - 5.7e-05 22.6 4.2 8.3 7.1 0.2 4.8 5 0 0 5 5 5 3 Leucine rich repeat LRR_6 PF13516.1 KLO20463.1 - 0.00025 20.7 2.5 1.2 9.4 0.5 4.6 4 1 1 5 5 5 1 Leucine Rich repeat Syja_N PF02383.13 KLO20464.1 - 8.6e-79 264.5 0.0 1.1e-78 264.2 0.0 1.1 1 0 0 1 1 1 1 SacI homology domain Pkinase PF00069.20 KLO20465.1 - 4.1e-41 140.8 0.0 5.8e-22 78.0 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 KLO20465.1 - 3.8e-10 39.2 0.0 1e-06 28.0 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Pox_ser-thr_kin PF05445.6 KLO20465.1 - 0.063 12.0 0.0 0.095 11.4 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase MSC PF09402.5 KLO20465.1 - 0.15 10.7 0.2 0.25 10.0 0.2 1.2 1 0 0 1 1 1 0 Man1-Src1p-C-terminal domain RVT_3 PF13456.1 KLO20466.1 - 8.8e-07 28.6 0.0 1.6e-06 27.8 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase-like Polysacc_deac_1 PF01522.16 KLO20467.1 - 1.5e-28 98.9 0.0 4e-28 97.5 0.0 1.7 1 0 0 1 1 1 1 Polysaccharide deacetylase SVWC PF15430.1 KLO20468.1 - 0.039 14.4 0.1 0.12 12.8 0.1 1.8 1 0 0 1 1 1 0 Single domain von Willebrand factor type C NAP PF00956.13 KLO20470.1 - 1.6e-31 109.2 9.1 3.2e-31 108.2 6.3 1.4 1 1 0 1 1 1 1 Nucleosome assembly protein (NAP) Nucleoplasmin PF03066.10 KLO20470.1 - 0.013 14.9 4.7 0.032 13.7 3.2 1.7 1 0 0 1 1 1 0 Nucleoplasmin YL1 PF05764.8 KLO20470.1 - 1.5 8.3 7.9 0.25 10.9 1.7 2.0 2 0 0 2 2 2 0 YL1 nuclear protein GDPD PF03009.12 KLO20471.1 - 1.6e-36 126.1 0.0 2.4e-36 125.5 0.0 1.3 1 1 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family GDPD_2 PF13653.1 KLO20471.1 - 3.5e-05 23.8 0.7 9.9e-05 22.4 0.1 2.1 2 0 0 2 2 2 1 Glycerophosphoryl diester phosphodiesterase family Rieske PF00355.21 KLO20472.1 - 1.4e-17 62.9 0.1 2.7e-17 62.1 0.0 1.4 1 1 0 1 1 1 1 Rieske [2Fe-2S] domain UCR_TM PF02921.9 KLO20472.1 - 3.9e-15 55.8 3.0 8.1e-15 54.8 2.1 1.6 1 0 0 1 1 1 1 Ubiquinol cytochrome reductase transmembrane region Pkinase PF00069.20 KLO20473.1 - 2.1e-51 174.6 0.0 8.1e-51 172.6 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KLO20473.1 - 4.2e-37 127.6 0.0 7.8e-21 74.3 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 KLO20473.1 - 0.0012 17.8 0.0 0.011 14.7 0.0 2.0 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 KLO20473.1 - 0.059 13.1 0.1 0.11 12.2 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family CHCH PF06747.8 KLO20475.1 - 2.3e-05 24.1 2.7 4e-05 23.4 1.9 1.4 1 0 0 1 1 1 1 CHCH domain Pet191_N PF10203.4 KLO20475.1 - 0.0055 16.7 2.2 0.032 14.2 1.6 1.9 1 1 1 2 2 2 1 Cytochrome c oxidase assembly protein PET191 COX17 PF05051.8 KLO20475.1 - 0.047 13.7 1.7 1 9.4 0.2 2.1 1 1 1 2 2 2 0 Cytochrome C oxidase copper chaperone (COX17) Cmc1 PF08583.5 KLO20475.1 - 0.21 11.4 2.4 4.1 7.2 1.8 2.1 1 1 1 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like bZIP_2 PF07716.10 KLO20476.1 - 4.5e-10 39.2 8.1 6.6e-09 35.4 5.5 2.2 1 1 1 2 2 2 2 Basic region leucine zipper bZIP_1 PF00170.16 KLO20476.1 - 3.8e-06 26.7 8.0 1.2e-05 25.1 5.6 1.8 1 1 0 1 1 1 1 bZIP transcription factor bZIP_Maf PF03131.12 KLO20476.1 - 0.0019 18.4 1.4 0.0031 17.7 1.0 1.3 1 0 0 1 1 1 1 bZIP Maf transcription factor Tropomyosin PF00261.15 KLO20476.1 - 0.0083 15.2 1.5 0.011 14.8 1.0 1.2 1 0 0 1 1 1 1 Tropomyosin DUF2216 PF10226.4 KLO20476.1 - 0.014 14.9 2.5 0.016 14.7 1.7 1.1 1 0 0 1 1 1 0 Uncharacterized conserved proteins (DUF2216) DUF4472 PF14739.1 KLO20476.1 - 0.017 15.5 0.5 0.026 14.9 0.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4472) IncA PF04156.9 KLO20476.1 - 0.092 12.3 0.3 0.12 12.0 0.2 1.1 1 0 0 1 1 1 0 IncA protein CASP_C PF08172.7 KLO20476.1 - 0.1 11.6 0.5 0.13 11.2 0.3 1.2 1 0 0 1 1 1 0 CASP C terminal Paf1 PF03985.8 KLO20476.1 - 8.8 4.9 8.7 6.8 5.3 5.4 1.2 1 1 0 1 1 1 0 Paf1 NPL4 PF05021.10 KLO20477.1 - 2.6e-99 332.2 0.0 3.8e-99 331.7 0.0 1.2 1 0 0 1 1 1 1 NPL4 family zf-NPL4 PF05020.10 KLO20477.1 - 1.7e-60 202.9 0.1 3.1e-60 202.0 0.0 1.4 1 0 0 1 1 1 1 NPL4 family, putative zinc binding region UN_NPL4 PF11543.3 KLO20477.1 - 0.00018 21.7 0.0 0.00042 20.5 0.0 1.7 1 0 0 1 1 1 1 Nuclear pore localisation protein NPL4 DZR PF12773.2 KLO20477.1 - 0.028 14.2 1.1 0.028 14.2 0.8 2.6 3 1 0 3 3 3 0 Double zinc ribbon GCC2_GCC3 PF07699.8 KLO20477.1 - 4.1 7.0 8.1 2.9 7.5 0.6 2.8 2 0 0 2 2 2 0 GCC2 and GCC3 ATP-synt_F PF01990.12 KLO20478.1 - 1.4e-32 111.8 0.2 1.7e-32 111.6 0.1 1.1 1 0 0 1 1 1 1 ATP synthase (F/14-kDa) subunit DXP_synthase_N PF13292.1 KLO20478.1 - 0.071 12.0 0.0 0.071 12.0 0.0 1.1 1 0 0 1 1 1 0 1-deoxy-D-xylulose-5-phosphate synthase CTX_RstB PF07459.6 KLO20478.1 - 0.13 12.1 0.1 0.19 11.5 0.0 1.3 1 1 0 1 1 1 0 CTX phage RstB protein PhaG_MnhG_YufB PF03334.9 KLO20479.1 - 0.012 15.5 0.3 0.043 13.8 0.2 2.0 1 1 0 1 1 1 0 Na+/H+ antiporter subunit TBPIP PF07106.8 KLO20480.1 - 1.2e-38 132.2 2.6 1.5e-38 132.0 1.8 1.1 1 0 0 1 1 1 1 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) bZIP_1 PF00170.16 KLO20480.1 - 0.0023 17.8 2.6 0.0023 17.8 1.8 1.8 2 0 0 2 2 1 1 bZIP transcription factor Penicillinase_R PF03965.11 KLO20480.1 - 0.0076 16.3 0.2 0.019 15.0 0.1 1.9 2 1 0 2 2 1 1 Penicillinase repressor BRCT PF00533.21 KLO20480.1 - 0.0084 16.2 0.0 2.5 8.3 0.0 3.2 2 1 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain DUF972 PF06156.8 KLO20480.1 - 0.036 14.4 2.9 0.078 13.3 2.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF972) CtIP_N PF10482.4 KLO20480.1 - 0.047 13.4 1.0 0.083 12.6 0.2 1.8 2 0 0 2 2 2 0 Tumour-suppressor protein CtIP N-terminal domain DUF668 PF05003.7 KLO20480.1 - 0.05 13.8 0.1 0.12 12.6 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF668) TrmB PF01978.14 KLO20480.1 - 0.067 12.9 0.7 0.85 9.3 0.0 2.9 3 1 1 4 4 4 0 Sugar-specific transcriptional regulator TrmB HSCB_C PF07743.8 KLO20480.1 - 0.079 13.4 2.3 0.2 12.1 1.6 1.7 1 0 0 1 1 1 0 HSCB C-terminal oligomerisation domain DUF4140 PF13600.1 KLO20480.1 - 0.088 13.2 2.0 0.17 12.3 0.4 2.1 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) CENP-H PF05837.7 KLO20480.1 - 0.11 12.7 6.5 0.045 13.9 2.3 1.9 2 0 0 2 2 2 0 Centromere protein H (CENP-H) IncA PF04156.9 KLO20480.1 - 0.12 12.0 2.3 0.15 11.6 1.6 1.2 1 0 0 1 1 1 0 IncA protein Seadorna_VP6 PF07407.6 KLO20480.1 - 0.21 10.3 0.4 0.27 9.9 0.3 1.1 1 0 0 1 1 1 0 Seadornavirus VP6 protein IFT20 PF14931.1 KLO20480.1 - 0.24 11.2 3.2 0.43 10.4 2.2 1.4 1 0 0 1 1 1 0 Intraflagellar transport complex B, subunit 20 DUF848 PF05852.6 KLO20480.1 - 0.58 9.9 5.0 1.4 8.7 3.2 1.7 1 1 1 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) Seryl_tRNA_N PF02403.17 KLO20480.1 - 0.7 9.9 5.6 0.79 9.7 2.7 2.0 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain TIM21 PF08294.6 KLO20481.1 - 1.3e-20 73.5 0.0 4.4e-19 68.5 0.0 2.2 2 0 0 2 2 2 2 TIM21 Histone PF00125.19 KLO20482.1 - 4.1e-30 103.7 0.8 6.9e-30 102.9 0.6 1.4 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 KLO20482.1 - 1.3e-05 25.2 0.1 2.2e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 Kinetochore component CENP-S CBFD_NFYB_HMF PF00808.18 KLO20482.1 - 0.0012 18.8 1.4 0.0014 18.6 0.1 1.7 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Bromo_TP PF07524.8 KLO20482.1 - 0.015 15.0 0.1 0.026 14.2 0.1 1.4 1 0 0 1 1 1 0 Bromodomain associated CENP-T PF15511.1 KLO20482.1 - 0.097 11.8 1.8 0.11 11.7 1.2 1.2 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T Catalase PF00199.14 KLO20483.1 - 7.6e-158 525.1 0.0 9.6e-158 524.8 0.0 1.1 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.7 KLO20483.1 - 1.1e-19 70.0 0.1 2.2e-19 69.0 0.0 1.6 1 0 0 1 1 1 1 Catalase-related immune-responsive DJ-1_PfpI PF01965.19 KLO20483.1 - 2.4e-11 43.3 0.0 4.2e-11 42.4 0.0 1.4 1 0 0 1 1 1 1 DJ-1/PfpI family zf-C2H2 PF00096.21 KLO20487.1 - 2.2e-09 37.0 21.3 1.4e-06 28.2 1.9 3.5 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 KLO20487.1 - 0.0028 17.8 21.6 0.006 16.8 1.6 3.4 3 0 0 3 3 3 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 KLO20487.1 - 0.04 14.2 17.1 0.67 10.3 2.2 3.5 3 0 0 3 3 3 0 Zinc-finger double domain DUF1610 PF07754.6 KLO20487.1 - 1.2 9.3 6.4 0.34 11.0 1.4 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1610) HAD_2 PF13419.1 KLO20488.1 - 7.2e-21 75.1 0.0 1.8e-16 60.8 0.0 2.1 2 0 0 2 2 2 2 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 KLO20488.1 - 2.6e-09 37.8 0.0 7.4e-09 36.3 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.1 KLO20488.1 - 0.00016 21.4 0.0 0.035 13.9 0.0 2.3 2 0 0 2 2 2 2 Haloacid dehalogenase-like hydrolase HAD PF12710.2 KLO20488.1 - 0.0011 19.1 0.0 0.0014 18.8 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 KLO20488.1 - 0.0028 17.3 0.0 0.0066 16.1 0.0 1.7 1 0 0 1 1 1 1 HAD-hyrolase-like EspF PF04806.7 KLO20488.1 - 0.12 12.6 6.0 1.2 9.3 0.1 2.9 4 0 0 4 4 4 0 EspF protein repeat SGT1 PF07093.6 KLO20489.1 - 1.2e-131 439.9 29.5 7.2e-131 437.4 20.5 1.9 1 1 0 1 1 1 1 SGT1 protein Clat_adaptor_s PF01217.15 KLO20490.1 - 1.8e-43 147.6 0.2 3.7e-43 146.6 0.2 1.4 1 1 0 1 1 1 1 Clathrin adaptor complex small chain Med6 PF04934.9 KLO20491.1 - 6.6e-39 132.6 0.1 1e-38 132.0 0.1 1.2 1 0 0 1 1 1 1 MED6 mediator sub complex component MIP-T3 PF10243.4 KLO20491.1 - 5.4 5.3 11.6 7.2 4.9 8.1 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Nramp PF01566.13 KLO20492.1 - 9e-90 301.0 19.7 2.8e-89 299.3 13.7 1.7 1 1 0 1 1 1 1 Natural resistance-associated macrophage protein Shisa PF13908.1 KLO20492.1 - 0.11 12.6 3.3 30 4.7 0.0 3.7 2 1 0 3 3 3 0 Wnt and FGF inhibitory regulator OAD_gamma PF04277.8 KLO20492.1 - 4.2 7.7 7.6 12 6.2 0.1 3.4 3 0 0 3 3 3 0 Oxaloacetate decarboxylase, gamma chain Chalcone PF02431.10 KLO20493.1 - 1.2e-29 103.1 0.0 2.8e-29 101.9 0.0 1.5 1 1 0 1 1 1 1 Chalcone-flavanone isomerase DUF3437 PF11919.3 KLO20494.1 - 2.2e-31 107.4 0.1 9.1e-31 105.4 0.0 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF3437) HEAT PF02985.17 KLO20494.1 - 0.001 18.9 1.0 0.024 14.6 0.0 3.8 3 0 0 3 3 3 1 HEAT repeat HEAT_2 PF13646.1 KLO20494.1 - 0.0058 16.8 1.3 0.66 10.3 0.0 4.9 5 0 0 5 5 5 1 HEAT repeats Cnd1 PF12717.2 KLO20494.1 - 0.037 13.8 0.1 7.5 6.3 0.0 3.8 4 0 0 4 4 4 0 non-SMC mitotic condensation complex subunit 1 zf-CCCH PF00642.19 KLO20496.1 - 4.5e-18 64.4 13.4 1.1e-09 37.7 1.5 2.3 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.1 KLO20496.1 - 0.14 12.1 11.5 0.073 13.0 0.7 2.6 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type Choline_kinase PF01633.15 KLO20497.1 - 9.6e-52 175.6 0.0 1.2e-51 175.2 0.0 1.1 1 0 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.18 KLO20497.1 - 1.7e-12 47.6 0.1 3e-12 46.7 0.1 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.15 KLO20497.1 - 0.0048 16.0 0.1 0.0085 15.2 0.1 1.3 1 0 0 1 1 1 1 Ecdysteroid kinase MFS_1 PF07690.11 KLO20499.1 - 2.2e-32 112.1 48.4 1.1e-31 109.8 33.6 2.1 1 1 0 1 1 1 1 Major Facilitator Superfamily CTDII PF01556.13 KLO20500.1 - 3.1e-30 103.8 0.3 6.2e-22 77.2 0.0 3.4 3 0 0 3 3 3 2 DnaJ C terminal domain DnaJ PF00226.26 KLO20500.1 - 8.7e-24 83.0 3.6 1.3e-23 82.4 2.5 1.3 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.14 KLO20500.1 - 2.4e-11 43.5 17.3 4.3e-11 42.6 12.0 1.5 1 0 0 1 1 1 1 DnaJ central domain SET PF00856.23 KLO20501.1 - 7.5e-09 36.1 0.0 1.2e-06 28.9 0.0 2.2 1 1 0 1 1 1 1 SET domain Pkinase PF00069.20 KLO20502.1 - 1.4e-59 201.4 0.2 1.6e-59 201.1 0.1 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KLO20502.1 - 6.4e-19 68.0 0.0 9.9e-19 67.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 KLO20502.1 - 3.8e-07 30.0 0.1 3.5e-05 23.6 0.2 2.5 1 1 1 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 KLO20502.1 - 0.023 14.2 0.1 0.023 14.2 0.1 1.8 2 0 0 2 2 2 0 Choline/ethanolamine kinase Kdo PF06293.9 KLO20502.1 - 0.051 12.6 0.2 0.095 11.7 0.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Aconitase_B_N PF11791.3 KLO20502.1 - 0.06 13.1 0.0 0.17 11.7 0.0 1.6 2 0 0 2 2 2 0 Aconitate B N-terminal domain Kinase-like PF14531.1 KLO20502.1 - 0.14 11.1 0.0 0.17 10.7 0.0 1.2 1 0 0 1 1 1 0 Kinase-like CBM_5_12 PF02839.9 KLO20503.1 - 1.2e-09 37.5 23.0 2.1e-07 30.3 6.7 4.2 4 0 0 4 4 4 2 Carbohydrate binding domain DIE2_ALG10 PF04922.7 KLO20504.1 - 9.7e-96 321.0 8.5 1.2e-95 320.7 5.9 1.1 1 0 0 1 1 1 1 DIE2/ALG10 family Methyltransf_26 PF13659.1 KLO20505.1 - 1.6e-07 31.3 0.0 2.7e-07 30.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 KLO20505.1 - 1.1e-06 28.1 0.0 1.6e-06 27.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain DNA_pol_A_exo1 PF01612.15 KLO20506.1 - 1.6e-10 40.7 0.0 2.5e-05 23.8 0.0 2.5 2 1 0 2 2 2 2 3'-5' exonuclease CAP_N PF01213.14 KLO20506.1 - 3.6 6.7 10.4 0.63 9.2 1.9 2.3 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal Pkinase PF00069.20 KLO20510.1 - 5.9e-09 35.4 0.0 2.1e-08 33.6 0.0 1.9 2 0 0 2 2 2 1 Protein kinase domain Kdo PF06293.9 KLO20510.1 - 0.0032 16.5 0.0 0.008 15.2 0.0 1.6 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_Tyr PF07714.12 KLO20510.1 - 0.013 14.6 0.0 0.021 13.9 0.0 1.3 1 0 0 1 1 1 0 Protein tyrosine kinase DUF3437 PF11919.3 KLO20513.1 - 1.4e-31 107.9 0.1 4.6e-31 106.3 0.1 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3437) HEAT PF02985.17 KLO20513.1 - 3.7e-09 35.8 0.3 0.0075 16.2 0.0 5.9 5 0 0 5 5 5 3 HEAT repeat HEAT_2 PF13646.1 KLO20513.1 - 5.8e-08 32.8 0.9 0.011 15.9 0.0 5.8 6 1 0 6 6 6 1 HEAT repeats Arm PF00514.18 KLO20513.1 - 0.0022 17.7 1.3 1.1 9.2 0.0 4.2 4 1 1 5 5 5 1 Armadillo/beta-catenin-like repeat CLASP_N PF12348.3 KLO20513.1 - 0.024 14.0 0.4 0.21 10.9 0.0 2.5 2 0 0 2 2 2 0 CLASP N terminal DUF1546 PF07571.8 KLO20513.1 - 0.044 13.8 0.0 1.1 9.4 0.0 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1546) Vac14_Fab1_bd PF12755.2 KLO20513.1 - 0.13 12.6 0.6 9.6 6.6 0.0 3.7 4 0 0 4 4 4 0 Vacuolar 14 Fab1-binding region RNase_T PF00929.19 KLO20515.1 - 2e-10 41.2 0.0 2.6e-10 40.8 0.0 1.2 1 0 0 1 1 1 1 Exonuclease BATS PF06968.8 KLO20516.1 - 2.8e-29 100.8 0.0 7e-29 99.5 0.0 1.7 1 0 0 1 1 1 1 Biotin and Thiamin Synthesis associated domain Radical_SAM PF04055.16 KLO20516.1 - 3.6e-17 63.0 0.0 5.6e-17 62.4 0.0 1.2 1 0 0 1 1 1 1 Radical SAM superfamily Ribosomal_S27e PF01667.12 KLO20517.1 - 3.5e-27 93.7 2.8 4.3e-27 93.4 1.9 1.1 1 0 0 1 1 1 1 Ribosomal protein S27 IBR PF01485.16 KLO20517.1 - 0.00085 19.1 1.1 0.0011 18.7 0.8 1.1 1 0 0 1 1 1 1 IBR domain Mu-like_Com PF10122.4 KLO20517.1 - 0.061 12.3 0.4 7.3 5.7 0.1 2.2 2 0 0 2 2 2 0 Mu-like prophage protein Com Zn_Tnp_IS1 PF03811.8 KLO20517.1 - 0.066 12.7 3.7 0.14 11.6 0.1 2.3 1 1 1 2 2 2 0 InsA N-terminal domain DUF3795 PF12675.2 KLO20517.1 - 0.11 12.6 1.9 1.3 9.2 1.3 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF3795) zinc_ribbon_4 PF13717.1 KLO20517.1 - 0.23 11.2 3.3 3.5 7.4 2.3 2.3 1 1 0 1 1 1 0 zinc-ribbon domain zinc_ribbon_5 PF13719.1 KLO20517.1 - 0.26 10.8 3.7 4 7.0 2.6 2.3 1 1 0 1 1 1 0 zinc-ribbon domain XPA_C PF05181.7 KLO20518.1 - 1.8e-28 97.8 2.8 3.3e-28 97.0 2.0 1.5 1 0 0 1 1 1 1 XPA protein C-terminus zf-AD PF07776.10 KLO20518.1 - 0.0095 15.9 0.7 4.8 7.2 0.5 2.6 2 0 0 2 2 2 2 Zinc-finger associated domain (zf-AD) PVL_ORF50 PF07768.6 KLO20518.1 - 0.33 10.9 13.1 0.86 9.6 3.2 3.0 3 0 0 3 3 3 0 PVL ORF-50-like family PWWP PF00855.12 KLO20518.1 - 0.41 10.8 3.5 0.17 12.0 0.6 1.9 2 0 0 2 2 2 0 PWWP domain FAM220 PF15487.1 KLO20518.1 - 0.94 8.7 6.0 1.6 8.0 4.2 1.3 1 0 0 1 1 1 0 FAM220 family FYVE PF01363.16 KLO20518.1 - 2.9 7.8 7.1 13 5.7 4.9 2.1 1 1 0 1 1 1 0 FYVE zinc finger Hist_deacetyl PF00850.14 KLO20519.1 - 4.5e-81 272.5 0.0 6.3e-81 272.0 0.0 1.2 1 0 0 1 1 1 1 Histone deacetylase domain DinB_2 PF12867.2 KLO20520.1 - 6.3e-06 26.5 0.0 7.5e-06 26.2 0.0 1.1 1 0 0 1 1 1 1 DinB superfamily BTG PF07742.7 KLO20521.1 - 7.3e-14 51.3 0.0 1.3e-13 50.4 0.0 1.4 1 0 0 1 1 1 1 BTG family VGCC_beta4Aa_N PF12052.3 KLO20521.1 - 0.069 13.0 0.0 0.069 13.0 0.0 2.0 2 1 0 2 2 2 0 Voltage gated calcium channel subunit beta domain 4Aa N terminal DUF442 PF04273.8 KLO20521.1 - 0.12 12.2 1.3 0.14 11.9 0.2 1.7 2 0 0 2 2 2 0 Putative phosphatase (DUF442) Translin PF01997.11 KLO20522.1 - 3.4e-51 173.6 0.1 4.1e-51 173.4 0.0 1.1 1 0 0 1 1 1 1 Translin family DcpS_C PF11969.3 KLO20523.1 - 0.00015 21.9 0.2 0.00096 19.3 0.0 2.0 2 0 0 2 2 2 1 Scavenger mRNA decapping enzyme C-term binding DUF2413 PF10310.4 KLO20524.1 - 2.1e-65 221.2 0.3 4.1e-64 217.0 0.2 2.5 1 1 0 1 1 1 1 Protein of unknown function (DUF2413) BCAS2 PF05700.6 KLO20525.1 - 6.6e-61 205.6 10.3 7.8e-61 205.3 7.1 1.0 1 0 0 1 1 1 1 Breast carcinoma amplified sequence 2 (BCAS2) DUF2380 PF09533.5 KLO20525.1 - 0.046 13.1 0.1 0.066 12.6 0.1 1.2 1 0 0 1 1 1 0 Predicted lipoprotein of unknown function (DUF2380) Syntaxin-6_N PF09177.6 KLO20525.1 - 5.3 7.5 7.9 2.7 8.4 1.5 2.8 2 1 1 3 3 3 0 Syntaxin 6, N-terminal Complex1_30kDa PF00329.14 KLO20526.1 - 1.4e-33 115.2 0.0 2.2e-33 114.5 0.0 1.3 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 30 Kd subunit ATP-grasp_2 PF08442.5 KLO20528.1 - 2.4e-73 245.8 0.1 4.1e-73 245.0 0.1 1.4 1 0 0 1 1 1 1 ATP-grasp domain Ligase_CoA PF00549.14 KLO20528.1 - 1.4e-24 86.4 0.5 2.5e-24 85.6 0.4 1.4 1 0 0 1 1 1 1 CoA-ligase ATP-grasp_5 PF13549.1 KLO20528.1 - 5.2e-12 45.4 0.3 2.5e-11 43.2 0.0 2.0 2 0 0 2 2 2 1 ATP-grasp domain GARS_A PF01071.14 KLO20528.1 - 0.001 18.7 0.0 0.0033 17.0 0.0 1.7 1 1 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain ATP-grasp_4 PF13535.1 KLO20528.1 - 0.001 18.8 0.0 0.002 17.8 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain Chromo PF00385.19 KLO20529.1 - 5.6e-07 29.1 0.6 1.2e-06 28.0 0.4 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Peptidase_C48 PF02902.14 KLO20530.1 - 9e-39 133.3 0.2 1.5e-38 132.5 0.1 1.3 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain Peptidase_C57 PF03290.8 KLO20530.1 - 0.043 12.3 0.6 0.07 11.6 0.4 1.3 1 0 0 1 1 1 0 Vaccinia virus I7 processing peptidase SNARE PF05739.14 KLO20531.1 - 1e-07 31.5 0.7 1.2e-07 31.3 0.5 1.1 1 0 0 1 1 1 1 SNARE domain DUF4234 PF14018.1 KLO20531.1 - 0.011 15.4 1.0 0.014 15.1 0.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4234) Sec20 PF03908.8 KLO20531.1 - 0.014 15.0 0.0 0.02 14.6 0.0 1.3 1 0 0 1 1 1 0 Sec20 Use1 PF09753.4 KLO20531.1 - 0.02 14.3 0.0 0.024 14.0 0.0 1.1 1 0 0 1 1 1 0 Membrane fusion protein Use1 RNB PF00773.14 KLO20532.1 - 4.3e-52 177.4 0.0 1.9e-51 175.3 0.0 1.9 2 0 0 2 2 2 1 RNB domain MtrD PF04207.7 KLO20533.1 - 0.0029 17.0 0.5 0.0059 16.0 0.4 1.4 1 0 0 1 1 1 1 Tetrahydromethanopterin S-methyltransferase, subunit D Chromate_transp PF02417.10 KLO20533.1 - 6.8 6.2 19.8 0.29 10.7 7.9 2.6 1 1 2 3 3 3 0 Chromate transporter PTH2 PF01981.11 KLO20534.1 - 4e-45 152.2 0.0 5e-45 151.9 0.0 1.1 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase PTH2 MFS_1 PF07690.11 KLO20535.1 - 3.8e-16 58.7 40.5 1.2e-14 53.7 13.8 3.0 1 1 2 3 3 3 3 Major Facilitator Superfamily Tim17 PF02466.14 KLO20536.1 - 5.6e-07 29.6 0.2 1.1e-06 28.7 0.1 1.5 2 0 0 2 2 2 1 Tim17/Tim22/Tim23/Pmp24 family BTB PF00651.26 KLO20537.1 - 0.05 13.6 0.0 0.15 12.0 0.0 1.8 1 1 1 2 2 2 0 BTB/POZ domain Sgf11 PF08209.6 KLO20538.1 - 1.9e-10 39.8 0.3 1.9e-10 39.8 0.2 1.6 2 0 0 2 2 2 1 Sgf11 (transcriptional regulation protein) BTB PF00651.26 KLO20539.1 - 5.5e-11 42.4 0.0 4e-10 39.6 0.0 2.1 1 1 0 1 1 1 1 BTB/POZ domain Yippee-Mis18 PF03226.9 KLO20542.1 - 4e-21 74.8 0.1 4.4e-21 74.7 0.1 1.0 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly GFA PF04828.9 KLO20542.1 - 0.0098 15.8 0.6 0.39 10.6 0.5 2.1 1 1 1 2 2 2 1 Glutathione-dependent formaldehyde-activating enzyme AlcCBM31 PF11606.3 KLO20542.1 - 0.01 15.7 0.1 0.61 10.0 0.0 2.1 1 1 1 2 2 2 0 Family 31 carbohydrate binding protein DZR PF12773.2 KLO20542.1 - 0.09 12.6 0.0 0.22 11.3 0.0 1.6 1 1 0 1 1 1 0 Double zinc ribbon Ribosomal_S27e PF01667.12 KLO20542.1 - 0.12 11.9 0.3 0.55 9.8 0.0 1.9 2 0 0 2 2 2 0 Ribosomal protein S27 MFS_1 PF07690.11 KLO20543.1 - 7.6e-23 80.7 27.8 3.5e-22 78.6 17.5 2.6 1 1 1 2 2 2 2 Major Facilitator Superfamily Ribosomal_L1 PF00687.16 KLO20544.1 - 1.4e-51 174.9 2.5 1.7e-51 174.6 1.7 1.0 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family DUF647 PF04884.9 KLO20544.1 - 0.0038 16.4 0.0 0.0047 16.1 0.0 1.3 1 0 0 1 1 1 1 Vitamin B6 photo-protection and homoeostasis SepQ PF06622.6 KLO20545.1 - 0.0021 16.9 0.2 0.003 16.5 0.1 1.4 1 0 0 1 1 1 1 SepQ protein Ras PF00071.17 KLO20548.1 - 4.6e-51 172.4 0.0 5.2e-51 172.2 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KLO20548.1 - 5.2e-15 55.9 0.0 7.5e-15 55.4 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein GTP_EFTU PF00009.22 KLO20548.1 - 1.6e-05 24.3 0.0 4.5e-05 22.9 0.0 1.5 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain Arf PF00025.16 KLO20548.1 - 3e-05 23.3 0.0 3.3e-05 23.1 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 KLO20548.1 - 0.00034 20.5 0.0 0.00041 20.2 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 KLO20548.1 - 0.004 16.4 0.1 0.074 12.3 0.1 2.6 1 1 0 1 1 1 1 Ferrous iron transport protein B Gtr1_RagA PF04670.7 KLO20548.1 - 0.03 13.4 0.0 0.037 13.1 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region AAA_24 PF13479.1 KLO20548.1 - 0.078 12.5 0.1 0.11 12.0 0.1 1.4 1 1 0 1 1 1 0 AAA domain SRPRB PF09439.5 KLO20548.1 - 0.086 12.0 0.0 0.12 11.5 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit CBS PF00571.23 KLO20549.1 - 6e-38 128.3 10.0 4.7e-10 39.0 0.0 4.9 5 0 0 5 5 5 4 CBS domain PB1 PF00564.19 KLO20549.1 - 5.9e-07 29.0 0.0 9.3e-06 25.2 0.0 2.5 2 0 0 2 2 2 1 PB1 domain SR-25 PF10500.4 KLO20549.1 - 0.0068 15.8 3.2 0.013 14.9 2.2 1.4 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein PfkB PF00294.19 KLO20550.1 - 1e-10 41.2 0.0 1.3e-10 40.9 0.0 1.2 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Phos_pyr_kin PF08543.7 KLO20550.1 - 0.019 14.1 0.0 0.027 13.6 0.0 1.2 1 0 0 1 1 1 0 Phosphomethylpyrimidine kinase UPF0121 PF03661.8 KLO20551.1 - 4.7e-20 71.8 0.5 6.6e-20 71.3 0.4 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0121) PTH2 PF01981.11 KLO20552.1 - 7.4e-39 132.0 0.6 2.1e-38 130.5 0.3 1.7 2 0 0 2 2 2 1 Peptidyl-tRNA hydrolase PTH2 DEAD PF00270.24 KLO20553.1 - 9.7e-43 145.5 0.0 1.9e-42 144.6 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 KLO20553.1 - 1.4e-21 76.1 0.0 2.5e-21 75.2 0.0 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF4217 PF13959.1 KLO20553.1 - 1.2e-18 66.4 0.3 2.4e-18 65.4 0.2 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) Trypan_PARP PF05887.6 KLO20553.1 - 0.021 14.6 1.0 0.04 13.7 0.7 1.4 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) PBP1_TM PF14812.1 KLO20553.1 - 0.023 15.0 8.1 0.19 12.0 6.5 1.9 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal PhoH PF02562.11 KLO20553.1 - 0.29 10.3 2.0 0.53 9.4 0.0 2.2 2 0 0 2 2 2 0 PhoH-like protein MCM PF00493.18 KLO20554.1 - 4.9e-127 423.2 0.1 6.9e-127 422.8 0.0 1.2 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 KLO20554.1 - 8.4e-19 68.2 0.0 2.9e-18 66.5 0.0 2.0 2 0 0 2 2 2 1 MCM N-terminal domain Mg_chelatase PF01078.16 KLO20554.1 - 9e-08 31.5 0.1 1.4e-06 27.6 0.0 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.6 KLO20554.1 - 0.0023 17.5 0.0 0.0087 15.6 0.0 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 KLO20554.1 - 0.0061 16.0 0.1 0.026 14.0 0.0 2.0 3 0 0 3 3 3 1 Sigma-54 interaction domain AAA_5 PF07728.9 KLO20554.1 - 0.028 14.1 0.2 0.12 12.0 0.0 2.3 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) DUF3512 PF12024.3 KLO20555.1 - 0.02 14.1 0.0 0.044 13.0 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3512) L51_S25_CI-B8 PF05047.11 KLO20556.1 - 4.2e-08 32.8 0.1 8.1e-08 31.8 0.1 1.5 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain PC_rep PF01851.17 KLO20560.1 - 7.8e-39 129.7 16.3 1e-07 31.7 0.0 9.4 10 0 0 10 10 10 7 Proteasome/cyclosome repeat HEAT_2 PF13646.1 KLO20560.1 - 9.5e-20 70.6 6.2 1.1e-10 41.5 0.1 4.5 2 1 3 5 5 5 5 HEAT repeats HEAT PF02985.17 KLO20560.1 - 2.7e-07 30.0 0.8 1.7 8.9 0.1 5.0 4 0 0 4 4 4 3 HEAT repeat HEAT_EZ PF13513.1 KLO20560.1 - 1.1e-05 25.8 5.6 0.018 15.5 0.0 4.9 4 0 0 4 4 4 2 HEAT-like repeat Arm PF00514.18 KLO20560.1 - 0.0053 16.5 1.4 3.7 7.5 0.0 4.4 4 0 0 4 4 4 1 Armadillo/beta-catenin-like repeat Cupredoxin_1 PF13473.1 KLO20561.1 - 2.8e-06 27.1 0.0 0.0053 16.6 0.0 2.8 3 0 0 3 3 3 2 Cupredoxin-like domain Cu_bind_like PF02298.12 KLO20561.1 - 0.00023 20.8 1.4 0.73 9.6 0.4 3.1 2 1 0 2 2 2 2 Plastocyanin-like domain AIP3 PF03915.8 KLO20563.1 - 0.16 10.8 0.5 0.25 10.1 0.3 1.2 1 0 0 1 1 1 0 Actin interacting protein 3 LIM PF00412.17 KLO20564.1 - 1.5e-13 50.6 24.8 3.3e-06 27.0 1.3 5.4 5 1 0 5 5 5 4 LIM domain DUF1720 PF08226.6 KLO20564.1 - 0.075 13.1 16.2 0.02 14.9 3.2 3.7 4 0 0 4 4 4 0 Domain of unknown function (DUF1720) Helitron_like_N PF14214.1 KLO20564.1 - 0.18 11.5 0.1 0.36 10.5 0.0 1.4 1 0 0 1 1 1 0 Helitron helicase-like domain at N-terminus DnaJ PF00226.26 KLO20566.1 - 1.3e-19 69.7 2.7 2e-19 69.0 1.9 1.3 1 0 0 1 1 1 1 DnaJ domain AMP-binding PF00501.23 KLO20569.1 - 2.1e-78 263.5 1.1 2.5e-78 263.3 0.8 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 KLO20569.1 - 2.2e-18 66.9 0.1 8.2e-18 65.1 0.0 2.0 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain GYF PF02213.11 KLO20570.1 - 1.9e-12 46.5 0.0 3.7e-12 45.6 0.0 1.5 1 0 0 1 1 1 1 GYF domain Cyclin_N PF00134.18 KLO20571.1 - 1.1e-11 44.3 0.0 2.2e-11 43.4 0.0 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain TFIIB PF00382.14 KLO20571.1 - 0.0052 16.5 0.0 0.031 14.0 0.0 2.1 2 0 0 2 2 2 1 Transcription factor TFIIB repeat AAA_18 PF13238.1 KLO20573.1 - 1.4e-28 99.8 0.7 3.6e-28 98.4 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 KLO20573.1 - 9e-18 65.2 0.4 2e-17 64.1 0.3 1.7 1 1 0 1 1 1 1 AAA domain SKI PF01202.17 KLO20573.1 - 5.8e-09 36.0 0.0 7.3e-09 35.6 0.0 1.1 1 0 0 1 1 1 1 Shikimate kinase ADK PF00406.17 KLO20573.1 - 4.4e-07 29.8 0.3 0.00012 21.9 0.0 2.2 2 0 0 2 2 2 1 Adenylate kinase AAA_33 PF13671.1 KLO20573.1 - 6.1e-05 22.9 0.4 0.0027 17.5 0.3 2.3 1 1 0 1 1 1 1 AAA domain AAA PF00004.24 KLO20573.1 - 0.00015 21.9 0.1 0.00057 20.1 0.0 1.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.1 KLO20573.1 - 0.0005 20.0 0.3 0.0013 18.7 0.0 1.9 2 1 0 2 2 2 1 AAA domain Thymidylate_kin PF02223.12 KLO20573.1 - 0.00099 18.5 0.7 0.85 8.9 0.1 2.1 2 0 0 2 2 2 2 Thymidylate kinase KTI12 PF08433.5 KLO20573.1 - 0.002 17.3 0.1 0.0062 15.7 0.0 1.8 2 0 0 2 2 2 1 Chromatin associated protein KTI12 AAA_22 PF13401.1 KLO20573.1 - 0.0023 18.0 0.2 0.0069 16.5 0.2 1.9 1 1 0 1 1 1 1 AAA domain NTPase_1 PF03266.10 KLO20573.1 - 0.0027 17.4 0.2 0.025 14.3 0.0 2.1 2 0 0 2 2 2 1 NTPase AAA_19 PF13245.1 KLO20573.1 - 0.0037 16.9 0.1 0.0064 16.2 0.1 1.3 1 0 0 1 1 1 1 Part of AAA domain AAA_16 PF13191.1 KLO20573.1 - 0.0043 17.0 0.0 0.015 15.2 0.0 1.9 2 0 0 2 2 2 1 AAA ATPase domain Cytidylate_kin2 PF13189.1 KLO20573.1 - 0.0069 16.3 0.2 0.34 10.7 0.0 2.2 1 1 1 2 2 2 1 Cytidylate kinase-like family AAA_10 PF12846.2 KLO20573.1 - 0.013 14.9 0.2 0.047 13.1 0.0 1.8 2 0 0 2 2 2 0 AAA-like domain KaiC PF06745.8 KLO20573.1 - 0.015 14.4 0.3 0.096 11.7 0.0 2.0 2 0 0 2 2 2 0 KaiC AAA_14 PF13173.1 KLO20573.1 - 0.016 15.0 0.4 0.078 12.8 0.2 2.0 1 1 0 1 1 1 0 AAA domain Zeta_toxin PF06414.7 KLO20573.1 - 0.019 14.0 0.2 0.049 12.7 0.0 1.7 2 0 0 2 2 2 0 Zeta toxin ABC_tran PF00005.22 KLO20573.1 - 0.023 14.9 0.2 0.044 14.0 0.2 1.7 1 1 0 1 1 1 0 ABC transporter T2SE PF00437.15 KLO20573.1 - 0.024 13.5 0.4 0.11 11.3 0.0 1.9 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_29 PF13555.1 KLO20573.1 - 0.025 14.1 0.0 0.056 12.9 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain RNA_helicase PF00910.17 KLO20573.1 - 0.03 14.5 0.0 0.065 13.4 0.0 1.6 2 0 0 2 2 1 0 RNA helicase DUF2075 PF09848.4 KLO20573.1 - 0.039 12.9 0.6 0.13 11.2 0.0 1.9 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) Sigma54_activat PF00158.21 KLO20573.1 - 0.073 12.5 0.0 0.12 11.8 0.0 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_25 PF13481.1 KLO20573.1 - 0.095 12.0 0.0 0.22 10.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.13 KLO20573.1 - 0.1 12.0 0.2 0.24 10.8 0.0 1.7 2 0 0 2 2 2 0 FtsK/SpoIIIE family DUF218 PF02698.12 KLO20573.1 - 0.15 11.5 0.2 6.2 6.2 0.1 2.2 2 0 0 2 2 2 0 DUF218 domain SRP54 PF00448.17 KLO20573.1 - 0.19 11.1 0.5 0.39 10.1 0.1 1.7 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_11 PF13086.1 KLO20573.1 - 0.21 11.1 2.1 0.68 9.4 1.4 1.8 1 1 0 1 1 1 0 AAA domain Ras PF00071.17 KLO20575.1 - 1.5e-55 186.9 0.0 1.9e-55 186.6 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 KLO20575.1 - 7.3e-18 65.1 0.0 1.1e-17 64.5 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 KLO20575.1 - 5.1e-15 55.1 0.0 4.4e-14 52.1 0.0 1.9 2 0 0 2 2 2 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 KLO20575.1 - 3.9e-06 26.4 0.0 6.7e-06 25.6 0.0 1.4 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 KLO20575.1 - 5.9e-06 25.5 0.0 6.5e-06 25.4 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 KLO20575.1 - 0.00038 20.3 0.0 0.00078 19.3 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase TCP PF03634.8 KLO20575.1 - 0.01 16.2 0.5 0.018 15.3 0.3 1.3 1 0 0 1 1 1 0 TCP family transcription factor AAA_16 PF13191.1 KLO20575.1 - 0.044 13.7 0.1 0.076 13.0 0.0 1.6 1 1 0 1 1 1 0 AAA ATPase domain Sin_N PF04801.8 KLO20576.1 - 1.9e-28 99.4 0.0 2.6e-28 99.0 0.0 1.1 1 0 0 1 1 1 1 Sin-like protein conserved region ARID PF01388.16 KLO20577.1 - 1.6e-10 40.6 0.0 5.1e-10 39.0 0.0 1.8 2 0 0 2 2 2 1 ARID/BRIGHT DNA binding domain FAD-oxidase_C PF02913.14 KLO20579.1 - 1.2e-49 168.8 0.0 1.6e-49 168.4 0.0 1.1 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.18 KLO20579.1 - 3.2e-34 117.3 0.5 5e-34 116.7 0.3 1.3 1 0 0 1 1 1 1 FAD binding domain Myb_DNA-bind_2 PF08914.6 KLO20580.1 - 5.2e-10 38.9 0.5 1.4e-09 37.5 0.3 1.7 1 0 0 1 1 1 1 Rap1 Myb domain Rap1-DNA-bind PF09197.5 KLO20580.1 - 0.016 15.7 2.0 0.14 12.7 1.4 2.2 1 1 0 1 1 1 0 Rap1, DNA-binding Pkinase PF00069.20 KLO20581.1 - 9.5e-68 228.1 0.0 1.2e-67 227.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KLO20581.1 - 9.1e-26 90.4 0.0 1.4e-25 89.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KLO20581.1 - 4.8e-06 25.7 0.0 7.2e-05 21.8 0.0 2.1 2 0 0 2 2 2 1 Kinase-like RIO1 PF01163.17 KLO20581.1 - 0.0016 17.8 0.0 0.0027 17.0 0.0 1.3 1 0 0 1 1 1 1 RIO1 family ABM PF03992.11 KLO20582.1 - 8.3e-12 44.9 0.0 1.1e-11 44.6 0.0 1.2 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase DUF4188 PF13826.1 KLO20582.1 - 0.047 13.7 0.0 0.051 13.6 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4188) ABM PF03992.11 KLO20583.1 - 3.2e-10 39.8 0.0 4e-10 39.5 0.0 1.1 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase ABM PF03992.11 KLO20584.1 - 4.9e-09 36.1 0.0 6.3e-09 35.7 0.0 1.2 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase ABM PF03992.11 KLO20585.1 - 5.8e-07 29.4 0.0 7.3e-07 29.1 0.0 1.2 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase ABM PF03992.11 KLO20586.1 - 8.2e-07 28.9 0.0 1.1e-06 28.6 0.0 1.2 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase ABM PF03992.11 KLO20587.1 - 2.3e-08 33.9 0.0 2.9e-08 33.6 0.0 1.2 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase Cu_bind_like PF02298.12 KLO20588.1 - 0.001 18.8 0.1 2.2 8.1 0.0 2.6 2 0 0 2 2 2 2 Plastocyanin-like domain DUF11 PF01345.13 KLO20588.1 - 1 9.4 5.9 1.8 8.6 0.1 3.0 3 0 0 3 3 3 0 Domain of unknown function DUF11 HCNGP PF07818.8 KLO20589.1 - 2.4e-24 85.1 0.1 3.2e-24 84.7 0.1 1.2 1 0 0 1 1 1 1 HCNGP-like protein Thioredoxin PF00085.15 KLO20590.1 - 1.1e-28 98.9 0.0 1.4e-28 98.6 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.1 KLO20590.1 - 7e-07 29.2 0.1 3.6e-06 27.0 0.0 1.8 1 1 0 1 1 1 1 Thioredoxin-like Thioredoxin_2 PF13098.1 KLO20590.1 - 6.8e-06 26.2 0.3 4.8e-05 23.5 0.2 2.0 1 1 0 1 1 1 1 Thioredoxin-like domain AhpC-TSA PF00578.16 KLO20590.1 - 1.1e-05 25.1 0.0 1.7e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_9 PF14595.1 KLO20590.1 - 4.7e-05 22.9 0.0 6e-05 22.6 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_7 PF13899.1 KLO20590.1 - 0.0058 16.6 0.1 0.012 15.6 0.0 1.5 1 1 0 1 1 1 1 Thioredoxin-like Redoxin PF08534.5 KLO20590.1 - 0.0063 16.0 0.0 0.0086 15.6 0.0 1.3 1 0 0 1 1 1 1 Redoxin Plasmod_MYXSPDY PF07981.6 KLO20591.1 - 0.15 11.7 0.5 0.36 10.5 0.3 1.6 1 0 0 1 1 1 0 Plasmodium repeat_MYXSPDY RabGAP-TBC PF00566.13 KLO20592.1 - 9.5e-31 106.9 0.0 1.6e-30 106.2 0.0 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Hex_IIIa PF02455.11 KLO20592.1 - 1.1 7.8 4.7 1.5 7.3 3.3 1.1 1 0 0 1 1 1 0 Hexon-associated protein (IIIa) CAF-1_p150 PF11600.3 KLO20592.1 - 8.8 5.6 10.6 19 4.5 7.3 1.5 1 1 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Spc97_Spc98 PF04130.8 KLO20593.1 - 4.3e-68 229.9 0.0 5.8e-68 229.5 0.0 1.2 1 0 0 1 1 1 1 Spc97 / Spc98 family Pyrophosphatase PF00719.14 KLO20594.1 - 3.9e-53 179.0 0.2 5.2e-53 178.6 0.2 1.2 1 0 0 1 1 1 1 Inorganic pyrophosphatase Pyocin_S PF06958.7 KLO20595.1 - 0.11 12.8 2.0 22 5.3 0.1 3.8 2 1 0 3 3 3 0 S-type Pyocin NTP_transf_2 PF01909.18 KLO20596.1 - 4.8e-07 30.0 0.0 1.2e-06 28.7 0.0 1.7 1 0 0 1 1 1 1 Nucleotidyltransferase domain PAP_assoc PF03828.14 KLO20596.1 - 1.8e-06 27.8 0.0 4e-06 26.6 0.0 1.6 1 0 0 1 1 1 1 Cid1 family poly A polymerase zf-C2H2_4 PF13894.1 KLO20597.1 - 1.9e-09 37.1 7.8 0.00017 21.6 2.0 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.21 KLO20597.1 - 7.4e-09 35.4 7.3 0.00025 21.1 2.0 2.5 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.3 KLO20597.1 - 0.021 14.9 3.3 0.12 12.5 0.1 2.3 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-H2C2_2 PF13465.1 KLO20597.1 - 0.048 13.9 8.2 0.3 11.4 0.6 3.5 3 0 0 3 3 3 0 Zinc-finger double domain zf-C2H2_6 PF13912.1 KLO20597.1 - 0.056 13.3 4.1 1.9 8.4 0.6 2.3 2 0 0 2 2 2 0 C2H2-type zinc finger zf-H2C2_5 PF13909.1 KLO20597.1 - 1.6 9.0 4.1 4 7.8 1.7 2.2 2 0 0 2 2 2 0 C2H2-type zinc-finger domain PfkB PF00294.19 KLO20598.1 - 2e-64 217.6 1.0 2.4e-64 217.3 0.7 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Phos_pyr_kin PF08543.7 KLO20598.1 - 0.00079 18.6 0.0 0.0018 17.4 0.0 1.6 2 0 0 2 2 2 1 Phosphomethylpyrimidine kinase RdRP PF05183.7 KLO20599.1 - 1.1e-106 357.8 0.0 1.5e-106 357.3 0.0 1.1 1 0 0 1 1 1 1 RNA dependent RNA polymerase RCC1 PF00415.13 KLO20600.1 - 1.7e-24 85.7 9.3 3.7e-08 33.4 0.2 7.3 6 2 0 6 6 6 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 KLO20600.1 - 1.4e-12 46.8 11.5 0.0045 16.5 0.0 6.3 6 1 0 6 6 6 4 Regulator of chromosome condensation (RCC1) repeat Swi5 PF07061.6 KLO20601.1 - 2.9e-16 59.0 0.8 3.6e-16 58.7 0.5 1.2 1 0 0 1 1 1 1 Swi5 Mnd1 PF03962.10 KLO20601.1 - 0.0028 17.3 0.7 0.0035 17.0 0.5 1.1 1 0 0 1 1 1 1 Mnd1 family TipAS PF07739.8 KLO20601.1 - 0.0045 17.3 0.6 0.0057 16.9 0.4 1.1 1 0 0 1 1 1 1 TipAS antibiotic-recognition domain DUF2209 PF09974.4 KLO20601.1 - 0.022 14.8 0.0 0.026 14.6 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2209) Lzipper-MIP1 PF14389.1 KLO20601.1 - 0.024 14.7 1.8 0.048 13.7 1.2 1.7 1 1 0 1 1 1 0 Leucine-zipper of ternary complex factor MIP1 P22_AR_C PF10548.4 KLO20601.1 - 0.046 13.6 0.0 0.061 13.1 0.0 1.2 1 0 0 1 1 1 0 P22AR C-terminal domain M16C_assoc PF08367.6 KLO20601.1 - 0.048 12.4 1.1 0.063 12.1 0.7 1.1 1 0 0 1 1 1 0 Peptidase M16C associated Fmp27_WPPW PF10359.4 KLO20601.1 - 0.062 11.7 0.4 0.069 11.5 0.2 1.1 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain Macoilin PF09726.4 KLO20601.1 - 0.065 11.5 0.4 0.07 11.4 0.3 1.0 1 0 0 1 1 1 0 Transmembrane protein bZIP_2 PF07716.10 KLO20601.1 - 0.069 12.9 2.0 0.081 12.7 0.3 1.8 2 0 0 2 2 2 0 Basic region leucine zipper DUF1912 PF08930.5 KLO20601.1 - 0.07 13.2 0.3 0.11 12.6 0.2 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF1912) DUF1192 PF06698.6 KLO20601.1 - 0.12 12.1 0.4 0.24 11.2 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1192) DUF342 PF03961.8 KLO20601.1 - 0.3 9.4 1.6 0.34 9.2 1.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF342) DUF837 PF05769.6 KLO20602.1 - 4.4e-07 29.6 17.5 3e-05 23.6 6.8 2.9 3 1 0 3 3 3 2 Protein of unknown function (DUF837) SlyX PF04102.7 KLO20602.1 - 0.14 12.5 0.4 0.14 12.5 0.3 4.7 5 1 1 6 6 6 0 SlyX DUF972 PF06156.8 KLO20602.1 - 0.15 12.4 10.2 0.12 12.6 1.6 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF972) NYD-SP28_assoc PF14775.1 KLO20602.1 - 0.5 10.1 17.4 0.35 10.5 1.0 4.4 4 1 0 4 4 4 0 Sperm tail C-terminal domain Mto2_bdg PF12808.2 KLO20602.1 - 0.6 10.2 8.9 1.4 9.0 0.1 3.5 3 0 0 3 3 3 0 Micro-tubular organiser Mto1 C-term Mto2-binding region DivIC PF04977.10 KLO20602.1 - 3.4 7.2 22.0 0.4 10.1 0.2 3.6 4 0 0 4 4 4 0 Septum formation initiator ABC_tran PF00005.22 KLO20603.1 - 7e-50 168.8 0.0 4.1e-24 85.4 0.0 2.5 2 0 0 2 2 2 2 ABC transporter ABC2_membrane_3 PF12698.2 KLO20603.1 - 1.8e-25 89.7 40.0 4.8e-15 55.4 14.9 2.2 2 0 0 2 2 2 2 ABC-2 family transporter protein AAA_21 PF13304.1 KLO20603.1 - 3.5e-21 76.4 0.1 7.8e-08 32.6 0.0 4.5 4 0 0 4 4 4 4 AAA domain AAA_23 PF13476.1 KLO20603.1 - 7.7e-06 26.3 1.3 0.091 13.0 0.0 2.4 2 0 0 2 2 2 2 AAA domain SMC_N PF02463.14 KLO20603.1 - 1.3e-05 24.5 1.8 0.055 12.6 0.1 3.9 3 1 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 KLO20603.1 - 0.0001 21.7 0.9 0.11 12.0 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain DUF258 PF03193.11 KLO20603.1 - 0.00027 20.1 0.1 0.61 9.2 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 DUF4162 PF13732.1 KLO20603.1 - 0.0006 20.2 0.1 0.21 12.0 0.0 2.5 2 0 0 2 2 2 1 Domain of unknown function (DUF4162) AAA_15 PF13175.1 KLO20603.1 - 0.00078 18.6 0.0 0.14 11.1 0.0 2.6 3 0 0 3 3 3 1 AAA ATPase domain AAA_22 PF13401.1 KLO20603.1 - 0.014 15.5 0.2 8.1 6.5 0.1 3.2 3 1 0 3 3 3 0 AAA domain ABC2_membrane PF01061.19 KLO20603.1 - 0.02 14.0 44.4 0.09 11.9 11.5 3.9 3 1 0 3 3 3 0 ABC-2 type transporter SRP54 PF00448.17 KLO20603.1 - 0.037 13.4 0.7 3.4 7.0 0.1 2.3 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_30 PF13604.1 KLO20603.1 - 0.056 13.0 1.7 11 5.4 0.0 3.1 3 0 0 3 3 3 0 AAA domain Zeta_toxin PF06414.7 KLO20603.1 - 0.14 11.1 0.1 8.6 5.3 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin Glutaredoxin PF00462.19 KLO20604.1 - 3.4e-10 39.7 0.0 5.4e-10 39.1 0.0 1.3 1 0 0 1 1 1 1 Glutaredoxin Thioredoxin_2 PF13098.1 KLO20604.1 - 0.059 13.5 0.0 0.14 12.3 0.0 1.7 2 0 0 2 2 2 0 Thioredoxin-like domain BRO1 PF03097.13 KLO20605.1 - 6.7e-18 64.5 0.0 9.3e-18 64.1 0.0 1.1 1 0 0 1 1 1 1 BRO1-like domain Vps5 PF09325.5 KLO20605.1 - 0.002 17.4 0.3 0.0046 16.2 0.0 1.6 2 0 0 2 2 2 1 Vps5 C terminal like Nup96 PF12110.3 KLO20607.1 - 6.8e-68 228.8 0.0 1.1e-67 228.1 0.0 1.4 1 0 0 1 1 1 1 Nuclear protein 96 Homeobox PF00046.24 KLO20608.1 - 6.6e-18 64.0 2.7 1.2e-17 63.2 1.8 1.5 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 KLO20608.1 - 1.6e-05 24.5 0.0 5.3e-05 22.8 0.0 1.8 1 0 0 1 1 1 1 Homeobox KN domain BrkDBD PF09607.5 KLO20608.1 - 0.085 12.4 0.1 0.14 11.7 0.1 1.4 1 0 0 1 1 1 0 Brinker DNA-binding domain Methyltransf_16 PF10294.4 KLO20609.1 - 5.5e-17 61.7 0.0 9.7e-17 60.9 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_18 PF12847.2 KLO20609.1 - 3.6e-06 27.5 0.0 1e-05 26.0 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 KLO20609.1 - 0.00039 20.8 0.0 0.00089 19.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 KLO20609.1 - 0.001 18.8 0.0 0.002 17.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 KLO20609.1 - 0.0025 17.4 0.0 0.0055 16.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 KLO20609.1 - 0.011 14.8 0.0 0.045 12.8 0.0 1.9 2 0 0 2 2 2 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_26 PF13659.1 KLO20609.1 - 0.022 14.8 0.0 0.048 13.7 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain MTS PF05175.9 KLO20609.1 - 0.032 13.6 0.1 0.068 12.5 0.1 1.6 1 1 0 1 1 1 0 Methyltransferase small domain zf-MYND PF01753.13 KLO20610.1 - 1.7e-07 31.0 17.2 3.2e-07 30.1 11.7 1.7 1 1 0 1 1 1 1 MYND finger Baculo_E25 PF05274.6 KLO20610.1 - 0.1 12.1 0.0 0.21 11.1 0.0 1.4 1 0 0 1 1 1 0 Occlusion-derived virus envelope protein E25 PolC_DP2 PF03833.8 KLO20610.1 - 2.2 5.8 4.1 3.2 5.2 2.9 1.1 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 TIP49 PF06068.8 KLO20612.1 - 7.8e-178 591.2 2.0 9.2e-178 590.9 1.4 1.0 1 0 0 1 1 1 1 TIP49 C-terminus AAA PF00004.24 KLO20612.1 - 9.2e-09 35.5 2.8 2.4e-06 27.7 0.0 3.3 3 2 1 4 4 4 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 KLO20612.1 - 3.3e-08 32.8 1.7 0.00044 19.3 0.0 2.8 2 1 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 KLO20612.1 - 6.4e-05 23.0 0.1 0.00073 19.5 0.0 2.4 2 1 0 2 2 2 1 AAA ATPase domain AAA_5 PF07728.9 KLO20612.1 - 0.00046 19.9 1.4 0.86 9.3 0.0 3.6 3 1 0 3 3 3 2 AAA domain (dynein-related subfamily) DnaB_C PF03796.10 KLO20612.1 - 0.002 17.0 0.2 0.0036 16.2 0.1 1.4 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain AAA_25 PF13481.1 KLO20612.1 - 0.0024 17.3 0.5 0.0062 15.9 0.3 1.8 1 1 0 1 1 1 1 AAA domain DNA_pol3_delta PF06144.8 KLO20612.1 - 0.0062 16.0 0.0 0.013 15.0 0.0 1.5 1 0 0 1 1 1 1 DNA polymerase III, delta subunit Mg_chelatase PF01078.16 KLO20612.1 - 0.0084 15.2 1.5 0.68 9.0 0.1 3.1 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI AAA_11 PF13086.1 KLO20612.1 - 0.045 13.3 0.0 0.092 12.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.1 KLO20612.1 - 0.072 12.9 0.0 0.17 11.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain Sipho_tail PF05709.6 KLO20612.1 - 0.094 11.8 0.0 0.16 11.0 0.0 1.4 1 0 0 1 1 1 0 Phage tail protein AAA_28 PF13521.1 KLO20612.1 - 0.13 12.1 1.3 0.16 11.8 0.0 1.8 2 0 0 2 2 2 0 AAA domain Ribosomal_L2_C PF03947.13 KLO20613.1 - 1.5e-49 167.1 0.2 2.9e-49 166.1 0.2 1.5 1 0 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.18 KLO20613.1 - 5.2e-24 84.0 0.4 9.3e-24 83.1 0.2 1.4 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain DUF4611 PF15387.1 KLO20614.1 - 0.099 12.7 1.6 0.11 12.5 1.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) Baculo_PEP_C PF04513.7 KLO20615.1 - 0.00092 19.0 13.9 0.048 13.4 5.0 2.6 1 1 1 2 2 2 2 Baculovirus polyhedron envelope protein, PEP, C terminus DUF948 PF06103.6 KLO20615.1 - 0.0012 18.6 0.2 0.055 13.3 0.0 2.6 1 1 2 3 3 3 1 Bacterial protein of unknown function (DUF948) Dicistro_VP4 PF11492.3 KLO20615.1 - 0.0023 17.8 2.0 0.038 14.0 0.1 3.0 3 0 0 3 3 3 1 Cricket paralysis virus, VP4 COG5 PF10392.4 KLO20615.1 - 0.017 15.0 0.2 0.07 13.0 0.1 1.9 2 0 0 2 2 2 0 Golgi transport complex subunit 5 Reo_sigmaC PF04582.7 KLO20615.1 - 0.02 14.0 8.1 0.012 14.7 3.7 1.6 1 1 1 2 2 2 0 Reovirus sigma C capsid protein Ribosomal_L21e PF01157.13 KLO20617.1 - 2.2e-39 133.2 4.5 3.1e-39 132.7 3.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L21e RNA_replicase_B PF03431.8 KLO20617.1 - 0.0048 15.1 0.3 0.0056 14.9 0.2 1.0 1 0 0 1 1 1 1 RNA replicase, beta-chain Ribosomal_S4 PF00163.14 KLO20618.1 - 1.2e-28 99.3 2.0 2.1e-28 98.5 1.4 1.4 1 0 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain S4 PF01479.20 KLO20618.1 - 8.6e-12 44.3 1.8 8.6e-12 44.3 1.2 2.7 3 0 0 3 3 3 1 S4 domain Dynactin PF12455.3 KLO20619.1 - 8.1e-81 270.9 4.5 8.1e-81 270.9 3.1 2.5 2 0 0 2 2 2 1 Dynein associated protein CAP_GLY PF01302.20 KLO20619.1 - 9.6e-23 79.6 0.7 2.5e-22 78.3 0.3 1.8 2 0 0 2 2 2 1 CAP-Gly domain Hist_deacetyl PF00850.14 KLO20620.1 - 5.1e-72 242.7 0.0 6.7e-72 242.4 0.0 1.1 1 0 0 1 1 1 1 Histone deacetylase domain C2 PF00168.25 KLO20621.1 - 4.9e-20 71.1 0.0 1e-13 50.9 0.0 2.6 2 0 0 2 2 2 2 C2 domain V-SNARE_C PF12352.3 KLO20622.1 - 2.6e-16 59.4 2.7 2.6e-16 59.4 1.9 2.5 3 0 0 3 3 3 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.8 KLO20622.1 - 0.0039 16.8 0.2 0.022 14.4 0.0 2.3 3 1 0 3 3 3 1 Sec20 AAA_13 PF13166.1 KLO20622.1 - 0.0077 14.7 0.1 0.0094 14.4 0.1 1.0 1 0 0 1 1 1 1 AAA domain Laminin_I PF06008.9 KLO20622.1 - 0.013 14.8 1.1 0.031 13.5 0.6 1.6 1 1 0 1 1 1 0 Laminin Domain I Occludin_ELL PF07303.8 KLO20622.1 - 0.016 15.9 0.1 1.1 10.0 0.0 2.8 1 1 0 2 2 2 0 Occludin homology domain MRFAP1 PF15155.1 KLO20622.1 - 0.14 12.4 1.9 0.24 11.7 1.0 1.6 1 1 0 1 1 1 0 MORF4 family-associated protein1 DUF1664 PF07889.7 KLO20622.1 - 0.15 11.8 0.5 6 6.6 0.0 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) FlgN PF05130.7 KLO20622.1 - 0.34 11.1 3.1 2 8.6 2.1 2.3 1 1 0 1 1 1 0 FlgN protein DUF848 PF05852.6 KLO20622.1 - 1.1 9.0 4.0 8.3 6.2 0.2 2.2 1 1 0 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) Tropomyosin_1 PF12718.2 KLO20622.1 - 1.8 8.3 4.5 1.3 8.8 0.5 2.2 1 1 0 2 2 2 0 Tropomyosin like HalX PF08663.5 KLO20622.1 - 4.9 7.2 9.3 3.1 7.8 0.2 3.4 2 2 2 4 4 4 0 HalX domain DUF726 PF05277.7 KLO20625.1 - 1.1e-123 412.4 1.7 1.7e-123 411.9 1.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF726) Abhydrolase_5 PF12695.2 KLO20625.1 - 0.0037 17.0 0.1 0.015 15.0 0.0 2.1 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 KLO20625.1 - 0.061 12.8 0.0 0.12 11.8 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_2 PF02230.11 KLO20625.1 - 0.16 11.4 0.1 0.48 9.8 0.0 1.8 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase TP1 PF02079.11 KLO20625.1 - 0.25 11.1 1.2 0.56 10.0 0.9 1.5 1 0 0 1 1 1 0 Nuclear transition protein 1 SRP14 PF02290.10 KLO20626.1 - 1.9e-24 85.3 0.0 4.1e-24 84.3 0.0 1.5 1 0 0 1 1 1 1 Signal recognition particle 14kD protein Ank_2 PF12796.2 KLO20627.1 - 5.8e-20 71.4 0.2 6.7e-12 45.5 0.0 2.1 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 KLO20627.1 - 3.7e-15 54.8 0.2 1.8e-06 27.4 0.0 3.9 3 1 0 3 3 3 3 Ankyrin repeat Ank_4 PF13637.1 KLO20627.1 - 4.3e-14 52.5 0.2 1.5e-06 28.5 0.0 3.1 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.1 KLO20627.1 - 2.3e-12 46.7 0.3 1.8e-06 28.0 0.1 3.0 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 KLO20627.1 - 5.1e-12 44.8 0.1 7.6e-06 25.6 0.0 3.8 4 0 0 4 4 4 2 Ankyrin repeat tRNA-synt_His PF13393.1 KLO20628.1 - 4.5e-39 134.3 0.1 8e-36 123.6 0.0 2.5 3 0 0 3 3 3 2 Histidyl-tRNA synthetase tRNA-synt_2b PF00587.20 KLO20628.1 - 1.2e-16 60.7 0.0 2e-16 60.0 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 KLO20628.1 - 1.5e-08 34.4 0.1 3.9e-08 33.1 0.1 1.7 1 0 0 1 1 1 1 Anticodon binding domain tRNA-synt_2 PF00152.15 KLO20628.1 - 0.0047 15.7 0.0 0.61 8.7 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class II (D, K and N) Ribosomal_60s PF00428.14 KLO20628.1 - 2.6 8.5 8.6 18 5.8 1.3 2.7 2 0 0 2 2 2 0 60s Acidic ribosomal protein ADH_N PF08240.7 KLO20631.1 - 5e-29 100.2 2.6 7.1e-29 99.7 0.1 2.2 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 KLO20631.1 - 5.5e-12 45.3 0.1 1.2e-09 37.7 0.0 2.3 2 0 0 2 2 2 2 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 KLO20631.1 - 0.00014 21.1 0.0 0.00025 20.2 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain QRPTase_C PF01729.14 KLO20631.1 - 0.0051 16.3 0.0 0.012 15.2 0.0 1.5 2 0 0 2 2 2 1 Quinolinate phosphoribosyl transferase, C-terminal domain Methyltransf_31 PF13847.1 KLO20631.1 - 0.016 14.8 0.0 0.024 14.2 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_18 PF12847.2 KLO20631.1 - 0.019 15.5 0.0 0.045 14.3 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain F420_oxidored PF03807.12 KLO20631.1 - 0.034 14.5 0.0 0.081 13.3 0.0 1.6 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent TrkA_N PF02254.13 KLO20631.1 - 0.15 12.1 0.0 0.27 11.2 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain Ribosomal_L17 PF01196.14 KLO20633.1 - 1.3e-34 118.6 0.0 1.5e-34 118.4 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L17 PP-binding PF00550.20 KLO20634.1 - 1.3e-13 51.0 1.1 1.8e-13 50.5 0.8 1.3 1 0 0 1 1 1 1 Phosphopantetheine attachment site PP-binding_2 PF14573.1 KLO20634.1 - 5.8e-07 29.4 0.1 7.6e-07 29.0 0.1 1.2 1 0 0 1 1 1 1 Acyl-carrier Ribosomal_L50 PF10501.4 KLO20634.1 - 0.015 15.2 0.0 0.021 14.7 0.0 1.4 1 1 0 1 1 1 0 Ribosomal subunit 39S DUF1493 PF07377.7 KLO20634.1 - 0.073 13.1 0.0 0.1 12.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) SGL PF08450.7 KLO20635.1 - 1.7e-68 230.6 0.0 1.9e-68 230.4 0.0 1.0 1 0 0 1 1 1 1 SMP-30/Gluconolaconase/LRE-like region Arylesterase PF01731.15 KLO20635.1 - 0.0017 18.2 0.0 0.0068 16.3 0.0 1.9 2 0 0 2 2 2 1 Arylesterase PQQ_3 PF13570.1 KLO20635.1 - 0.047 13.9 0.2 14 6.0 0.0 3.4 3 0 0 3 3 3 0 PQQ-like domain NHL PF01436.16 KLO20635.1 - 0.053 13.5 0.5 15 5.8 0.0 3.4 3 0 0 3 3 3 0 NHL repeat PQQ_2 PF13360.1 KLO20635.1 - 0.058 12.8 0.0 1.4 8.3 0.0 2.5 1 1 1 2 2 2 0 PQQ-like domain Aminotran_1_2 PF00155.16 KLO20637.1 - 9.1e-91 304.5 0.0 1e-90 304.3 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II tRNA-synt_2 PF00152.15 KLO20638.1 - 3e-79 266.2 0.3 5.2e-79 265.4 0.2 1.3 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 KLO20638.1 - 4.2e-05 23.3 0.1 8.2e-05 22.3 0.1 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain FtsH_ext PF06480.10 KLO20638.1 - 0.012 15.7 0.0 0.037 14.1 0.0 1.8 1 1 0 1 1 1 0 FtsH Extracellular tRNA-synt_2d PF01409.15 KLO20638.1 - 0.028 13.6 2.2 1 8.5 0.0 2.9 4 0 0 4 4 4 0 tRNA synthetases class II core domain (F) CBM_1 PF00734.13 KLO20639.1 - 1.2e-12 47.2 9.4 3.1e-12 45.9 6.5 1.8 1 0 0 1 1 1 1 Fungal cellulose binding domain BNR PF02012.15 KLO20639.1 - 8.6e-11 39.9 29.7 0.038 13.7 0.2 9.2 8 0 0 8 8 8 7 BNR/Asp-box repeat LRR_4 PF12799.2 KLO20640.1 - 8e-13 47.6 18.8 0.00019 20.9 0.1 7.3 5 2 2 7 7 7 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KLO20640.1 - 1.8e-10 40.4 11.0 0.0029 17.3 0.1 4.9 5 1 0 5 5 5 3 Leucine rich repeat LRR_6 PF13516.1 KLO20640.1 - 9.5e-10 37.5 10.7 1.1 9.5 0.0 9.5 11 0 0 11 11 11 3 Leucine Rich repeat LRR_1 PF00560.28 KLO20640.1 - 9.9e-05 21.8 13.2 1.2 9.3 0.0 8.0 7 2 0 7 7 7 1 Leucine Rich Repeat LRR_7 PF13504.1 KLO20640.1 - 0.99 9.8 13.8 15 6.3 0.0 7.3 9 0 0 9 9 9 0 Leucine rich repeat Vps51 PF08700.6 KLO20641.1 - 5.9e-13 48.4 1.0 2.1e-12 46.7 0.7 1.9 1 0 0 1 1 1 1 Vps51/Vps67 DUF4430 PF14478.1 KLO20642.1 - 0.011 15.8 0.0 0.024 14.6 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4430) DUF4198 PF10670.4 KLO20642.1 - 0.056 13.4 0.4 1.1 9.2 0.3 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF4198) CarboxypepD_reg PF13620.1 KLO20642.1 - 0.068 13.2 0.4 0.4 10.7 0.3 2.3 1 1 0 1 1 1 0 Carboxypeptidase regulatory-like domain DUF1751 PF08551.5 KLO20643.1 - 1e-27 96.3 6.0 2.1e-27 95.3 4.1 1.6 1 0 0 1 1 1 1 Eukaryotic integral membrane protein (DUF1751) DER1 PF04511.10 KLO20643.1 - 2.2 7.7 14.1 4.6 6.7 9.8 1.5 1 1 0 1 1 1 0 Der1-like family DUF1754 PF08555.5 KLO20644.1 - 9e-13 48.6 14.9 9e-13 48.6 10.4 1.5 1 1 1 2 2 2 1 Eukaryotic family of unknown function (DUF1754) DUF1104 PF06518.6 KLO20644.1 - 0.05 13.7 2.6 0.05 13.7 1.8 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1104) DUF1510 PF07423.6 KLO20644.1 - 0.24 10.7 12.0 0.32 10.3 8.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) HeLo PF14479.1 KLO20644.1 - 0.58 9.8 5.7 0.72 9.5 4.0 1.1 1 0 0 1 1 1 0 Prion-inhibition and propagation HSP70 PF00012.15 KLO20644.1 - 0.6 7.9 7.4 0.69 7.7 5.2 1.0 1 0 0 1 1 1 0 Hsp70 protein DUF4407 PF14362.1 KLO20644.1 - 0.75 8.6 4.0 0.98 8.3 2.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) MRP-L28 PF09812.4 KLO20644.1 - 0.88 9.3 9.4 1.1 9.0 6.5 1.0 1 0 0 1 1 1 0 Mitochondrial ribosomal protein L28 FAM60A PF15396.1 KLO20644.1 - 1.6 8.4 10.4 1.9 8.1 7.2 1.2 1 0 0 1 1 1 0 Protein Family FAM60A U79_P34 PF03064.11 KLO20644.1 - 4 6.8 18.0 5.9 6.3 12.5 1.3 1 1 0 1 1 1 0 HSV U79 / HCMV P34 Adaptin_binding PF10199.4 KLO20644.1 - 4.2 7.6 13.0 5.6 7.2 9.0 1.1 1 0 0 1 1 1 0 Alpha and gamma adaptin binding protein p34 SRP-alpha_N PF04086.8 KLO20644.1 - 4.3 6.6 18.5 5.2 6.3 12.9 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal BNIP3 PF06553.7 KLO20644.1 - 5 6.4 11.0 7.8 5.8 7.6 1.3 1 1 0 1 1 1 0 BNIP3 Asp-B-Hydro_N PF05279.6 KLO20644.1 - 8.8 6.1 13.4 11 5.7 9.3 1.1 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region WHIM2 PF15613.1 KLO20645.1 - 0.012 15.5 0.1 0.033 14.1 0.0 1.7 1 0 0 1 1 1 0 WSTF, HB1, Itc1p, MBD9 motif 2 DUF1192 PF06698.6 KLO20645.1 - 5 7.0 6.4 9.6 6.1 2.1 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1192) Peptidase_M3 PF01432.15 KLO20646.1 - 4.2e-125 418.3 0.0 5.6e-125 417.9 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M3 Homeobox_KN PF05920.6 KLO20647.1 - 2.1e-14 52.9 0.3 6.2e-14 51.4 0.2 1.9 1 0 0 1 1 1 1 Homeobox KN domain Mating_N PF12731.2 KLO20647.1 - 2.2e-06 27.4 1.1 5.6e-06 26.1 0.8 1.7 1 0 0 1 1 1 1 Mating-type protein beta 1 Homeobox PF00046.24 KLO20647.1 - 0.0016 17.9 0.0 0.0042 16.6 0.0 1.7 1 0 0 1 1 1 1 Homeobox domain Homeobox PF00046.24 KLO20648.1 - 5.6e-16 57.9 2.7 1.6e-15 56.4 1.8 1.8 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 KLO20648.1 - 3.4e-07 29.8 1.0 8.5e-07 28.5 0.7 1.7 1 0 0 1 1 1 1 Homeobox KN domain Homez PF11569.3 KLO20648.1 - 0.012 14.6 0.1 0.032 13.2 0.0 1.7 2 0 0 2 2 2 0 Homeodomain leucine-zipper encoding, Homez Homeobox_KN PF05920.6 KLO20649.1 - 8e-15 54.2 0.1 2.3e-14 52.8 0.0 1.9 1 0 0 1 1 1 1 Homeobox KN domain Homeobox PF00046.24 KLO20649.1 - 2.1e-06 27.2 0.0 7.4e-06 25.4 0.0 1.9 1 0 0 1 1 1 1 Homeobox domain Mating_N PF12731.2 KLO20649.1 - 0.0075 16.1 0.2 0.025 14.4 0.1 1.8 1 0 0 1 1 1 1 Mating-type protein beta 1 Homeobox PF00046.24 KLO20650.1 - 5e-14 51.6 0.6 1.1e-13 50.6 0.4 1.6 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 KLO20650.1 - 5.1e-09 35.6 0.7 3.9e-08 32.8 0.2 2.6 3 0 0 3 3 3 1 Homeobox KN domain Homez PF11569.3 KLO20650.1 - 0.00011 21.1 0.0 0.00021 20.3 0.0 1.4 1 0 0 1 1 1 1 Homeodomain leucine-zipper encoding, Homez Glyco_transf_8 PF01501.15 KLO20651.1 - 3e-31 108.6 0.0 5.5e-31 107.8 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 8 Mannosyl_trans3 PF11051.3 KLO20651.1 - 0.026 13.8 0.0 0.026 13.8 0.0 1.7 2 0 0 2 2 2 0 Mannosyltransferase putative MFS_1 PF07690.11 KLO20652.1 - 7.3e-43 146.6 34.0 1.3e-40 139.1 13.8 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 KLO20652.1 - 4.2e-05 22.1 3.5 4.2e-05 22.1 2.4 3.3 2 1 1 3 3 3 2 MFS/sugar transport protein TRI12 PF06609.8 KLO20652.1 - 6.7e-05 21.2 7.7 0.00011 20.6 5.3 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF3353 PF11833.3 KLO20652.1 - 0.45 9.9 4.5 1.2 8.5 3.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3353) DUF4131 PF13567.1 KLO20652.1 - 6.1 6.2 12.6 2 7.7 0.8 3.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4131) Apolipoprotein PF01442.13 KLO20654.1 - 9.5e-15 54.6 22.7 4.9e-10 39.2 5.7 2.3 1 1 1 2 2 2 2 Apolipoprotein A1/A4/E domain MT0933_antitox PF14013.1 KLO20654.1 - 1.4e-05 25.1 11.5 0.19 11.8 0.1 4.8 3 1 2 5 5 5 4 MT0933-like antitoxin protein DUF883 PF05957.8 KLO20654.1 - 0.026 14.9 21.0 1.2 9.5 2.3 4.4 2 2 2 4 4 4 0 Bacterial protein of unknown function (DUF883) DUF4456 PF14644.1 KLO20654.1 - 0.11 11.7 3.6 0.18 10.9 0.8 2.2 2 1 0 2 2 2 0 Domain of unknown function (DUF4456) SNase PF00565.12 KLO20654.1 - 0.15 12.3 4.9 6.2 7.1 0.6 3.7 1 1 2 3 3 3 0 Staphylococcal nuclease homologue Activator-TraM PF11657.3 KLO20654.1 - 0.18 11.3 10.3 0.078 12.4 1.9 3.1 2 2 1 3 3 3 0 Transcriptional activator TraM YtxH PF12732.2 KLO20654.1 - 0.18 12.1 16.2 1.5e+04 -5.2 11.2 4.3 1 1 0 1 1 0 0 YtxH-like protein ApoO PF09769.4 KLO20654.1 - 0.36 10.5 7.8 11 5.7 2.3 3.2 1 1 1 2 2 2 0 Apolipoprotein O AIP3 PF03915.8 KLO20654.1 - 0.45 9.3 6.1 2.3 7.0 4.3 1.9 1 1 0 1 1 1 0 Actin interacting protein 3 Phasin_2 PF09361.5 KLO20654.1 - 0.76 9.8 22.4 0.81 9.7 1.2 4.6 3 2 2 5 5 5 0 Phasin protein ATP-synt_B PF00430.13 KLO20654.1 - 9.2 6.0 24.4 1.5 8.6 3.1 4.1 1 1 1 4 4 4 0 ATP synthase B/B' CF(0) ABC1 PF03109.11 KLO20655.1 - 3.6e-22 78.5 0.0 1.3e-13 50.9 0.0 2.4 2 0 0 2 2 2 2 ABC1 family PX PF00787.19 KLO20658.1 - 1.6e-22 79.4 0.3 3.5e-22 78.3 0.2 1.5 1 0 0 1 1 1 1 PX domain Vps5 PF09325.5 KLO20658.1 - 1.1e-08 34.6 5.1 4.4e-06 26.1 1.3 2.3 2 0 0 2 2 2 2 Vps5 C terminal like RNA_pol_Rpb2_6 PF00562.23 KLO20659.1 - 1.6e-127 425.4 0.1 2.5e-127 424.8 0.1 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.10 KLO20659.1 - 5.4e-68 227.9 0.0 7.9e-68 227.3 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.9 KLO20659.1 - 1.2e-47 161.8 0.1 3.5e-47 160.2 0.0 1.8 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_7 PF04560.15 KLO20659.1 - 2.4e-29 101.4 0.0 5.4e-29 100.2 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_4 PF04566.8 KLO20659.1 - 2.8e-27 94.3 2.9 7.1e-27 93.0 2.0 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_3 PF04565.11 KLO20659.1 - 5.6e-24 83.6 0.1 1.3e-23 82.5 0.1 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_5 PF04567.12 KLO20659.1 - 1e-22 79.7 0.3 2.3e-22 78.6 0.2 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 Lung_7-TM_R PF06814.8 KLO20660.1 - 6.7e-57 192.6 17.9 8.1e-57 192.4 12.4 1.1 1 0 0 1 1 1 1 Lung seven transmembrane receptor tRNA-synt_2b PF00587.20 KLO20667.1 - 1.7e-28 99.3 0.0 2.5e-28 98.7 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.17 KLO20667.1 - 1.4e-08 34.7 0.1 2.3e-08 34.0 0.0 1.3 1 0 0 1 1 1 1 Seryl-tRNA synthetase N-terminal domain TSC22 PF01166.13 KLO20667.1 - 0.012 15.5 0.2 0.024 14.5 0.1 1.4 1 0 0 1 1 1 0 TSC-22/dip/bun family DUF2205 PF10224.4 KLO20667.1 - 0.016 14.7 0.2 0.029 13.9 0.1 1.3 1 0 0 1 1 1 0 Predicted coiled-coil protein (DUF2205) Rep_fac_C PF08542.6 KLO20668.1 - 1.4e-21 76.2 0.0 3.2e-21 75.1 0.0 1.7 1 0 0 1 1 1 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.1 KLO20668.1 - 7.7e-12 45.1 0.1 3.6e-10 39.7 0.0 2.2 1 1 0 1 1 1 1 DNA polymerase III, delta subunit AAA PF00004.24 KLO20668.1 - 1.2e-11 44.9 0.1 2.3e-11 43.9 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.1 KLO20668.1 - 1.5e-07 31.3 0.0 3e-07 30.3 0.0 1.6 2 0 0 2 2 1 1 AAA domain AAA_16 PF13191.1 KLO20668.1 - 5.7e-07 29.6 0.0 1.6e-05 25.0 0.0 2.2 1 1 1 2 2 2 1 AAA ATPase domain Rad17 PF03215.10 KLO20668.1 - 1.3e-06 27.4 0.1 0.014 14.0 0.0 2.2 1 1 1 2 2 2 2 Rad17 cell cycle checkpoint protein AAA_22 PF13401.1 KLO20668.1 - 1.9e-06 28.0 0.1 0.00029 20.9 0.1 2.5 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.7 KLO20668.1 - 6.4e-06 25.3 0.0 1.9e-05 23.8 0.0 1.7 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_3 PF07726.6 KLO20668.1 - 2.5e-05 23.9 0.0 4.9e-05 22.9 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Viral_helicase1 PF01443.13 KLO20668.1 - 0.00012 21.7 0.0 0.00018 21.1 0.0 1.2 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase AAA_10 PF12846.2 KLO20668.1 - 0.00029 20.4 0.2 0.17 11.2 0.0 2.5 2 1 1 3 3 3 2 AAA-like domain Mg_chelatase PF01078.16 KLO20668.1 - 0.0011 18.1 0.0 0.016 14.3 0.0 2.2 1 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI NTPase_1 PF03266.10 KLO20668.1 - 0.002 17.8 0.2 0.0083 15.8 0.1 2.0 1 1 1 2 2 2 1 NTPase DNA_pol3_delta PF06144.8 KLO20668.1 - 0.0022 17.5 0.1 0.0035 16.8 0.1 1.3 1 0 0 1 1 1 1 DNA polymerase III, delta subunit ArgK PF03308.11 KLO20668.1 - 0.0023 16.7 0.0 0.0086 14.8 0.0 1.8 1 1 1 2 2 2 1 ArgK protein AAA_19 PF13245.1 KLO20668.1 - 0.0054 16.4 0.0 0.011 15.4 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain AAA_18 PF13238.1 KLO20668.1 - 0.0089 16.3 0.0 0.017 15.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_31 PF13614.1 KLO20668.1 - 0.013 15.4 0.0 0.42 10.5 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_11 PF13086.1 KLO20668.1 - 0.019 14.5 0.0 0.024 14.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 KLO20668.1 - 0.021 14.9 0.1 0.14 12.3 0.1 2.4 2 1 0 2 2 2 0 RNA helicase DEAD PF00270.24 KLO20668.1 - 0.029 13.8 0.1 0.57 9.6 0.0 2.4 1 1 0 2 2 2 0 DEAD/DEAH box helicase AAA_5 PF07728.9 KLO20668.1 - 0.029 14.0 0.0 0.066 12.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) FtsK_SpoIIIE PF01580.13 KLO20668.1 - 0.038 13.4 0.0 0.09 12.2 0.0 1.6 1 0 0 1 1 1 0 FtsK/SpoIIIE family SRP54 PF00448.17 KLO20668.1 - 0.075 12.4 0.1 0.2 11.0 0.0 1.6 1 1 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_17 PF13207.1 KLO20668.1 - 0.087 13.6 0.5 0.22 12.3 0.3 1.8 1 1 0 1 1 1 0 AAA domain ABC_tran PF00005.22 KLO20668.1 - 0.12 12.6 0.1 0.33 11.2 0.0 1.7 1 1 0 1 1 1 0 ABC transporter VHS PF00790.14 KLO20669.1 - 1.2e-26 93.0 0.1 3.6e-26 91.4 0.0 1.8 2 1 0 2 2 2 1 VHS domain GAT PF03127.9 KLO20669.1 - 1.3e-06 28.3 4.2 3.2e-06 27.0 2.9 1.7 1 0 0 1 1 1 1 GAT domain ParA PF10609.4 KLO20670.1 - 3.2e-32 110.2 0.0 4.6e-32 109.7 0.0 1.2 1 0 0 1 1 1 1 ParA/MinD ATPase like CbiA PF01656.18 KLO20670.1 - 1.6e-05 24.3 0.0 2.3e-05 23.8 0.0 1.2 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain RRM_1 PF00076.17 KLO20673.1 - 5e-16 58.0 0.0 1.8e-07 30.6 0.0 3.4 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KLO20673.1 - 6.8e-15 54.8 0.0 2.7e-07 30.4 0.0 2.8 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KLO20673.1 - 3.3e-12 46.0 0.1 0.00021 21.0 0.0 3.3 4 0 0 4 4 4 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RNA_pol_Rpb6 PF01192.17 KLO20674.1 - 6.3e-23 80.2 0.3 8.5e-23 79.8 0.2 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb6 Ribonuclease_T2 PF00445.13 KLO20675.1 - 4.5e-31 107.9 0.0 6.8e-31 107.3 0.0 1.3 1 0 0 1 1 1 1 Ribonuclease T2 family Myb_DNA-binding PF00249.26 KLO20678.1 - 8.8e-07 28.8 0.0 2e-06 27.7 0.0 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 KLO20678.1 - 0.0008 19.4 0.1 0.002 18.2 0.1 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain SURF1 PF02104.10 KLO20680.1 - 3.2e-57 193.8 0.0 3.8e-57 193.5 0.0 1.0 1 0 0 1 1 1 1 SURF1 family ANTH PF07651.11 KLO20681.1 - 5.8e-74 248.3 1.4 1.6e-72 243.5 0.0 3.0 2 0 0 2 2 2 1 ANTH domain I_LWEQ PF01608.12 KLO20681.1 - 4.1e-63 211.8 9.4 4.1e-63 211.8 6.5 4.7 5 2 1 6 6 6 1 I/LWEQ domain ENTH PF01417.15 KLO20681.1 - 5.1e-06 26.3 0.0 5.4e-05 23.0 0.0 2.9 2 0 0 2 2 2 1 ENTH domain EthD PF07110.6 KLO20683.1 - 2.6e-09 37.8 0.5 0.0036 18.1 0.0 2.4 2 0 0 2 2 2 2 EthD domain DUF4286 PF14114.1 KLO20683.1 - 1.9e-07 31.2 0.1 0.0049 17.1 0.1 2.5 2 2 0 2 2 2 2 Domain of unknown function (DUF4286) Mvb12 PF09452.5 KLO20683.1 - 0.089 12.9 0.2 0.41 10.8 0.0 2.1 2 0 0 2 2 2 0 ESCRT-I subunit Mvb12 Ion_trans PF00520.26 KLO20684.1 - 3.1e-06 26.5 1.8 5.5e-06 25.7 1.3 1.4 1 0 0 1 1 1 1 Ion transport protein CWC25 PF12542.3 KLO20685.1 - 6e-23 81.1 0.1 6e-23 81.1 0.1 3.9 3 2 2 5 5 5 1 Pre-mRNA splicing factor Cir_N PF10197.4 KLO20685.1 - 3.2e-13 49.4 13.0 3.2e-13 49.4 9.0 5.2 5 1 1 6 6 6 1 N-terminal domain of CBF1 interacting co-repressor CIR DUF1754 PF08555.5 KLO20685.1 - 0.014 15.9 16.6 0.014 15.9 11.5 3.0 2 1 1 3 3 3 0 Eukaryotic family of unknown function (DUF1754) Oxidored_FMN PF00724.15 KLO20688.1 - 2.5e-57 194.4 0.0 3.3e-57 194.0 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family p450 PF00067.17 KLO20689.1 - 1.6e-80 270.8 0.0 1.5e-79 267.7 0.0 1.9 1 1 0 1 1 1 1 Cytochrome P450 3Beta_HSD PF01073.14 KLO20690.1 - 2e-17 62.8 0.0 5e-09 35.2 0.0 2.1 1 1 1 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 KLO20690.1 - 2.7e-16 60.1 0.1 4e-16 59.5 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 KLO20690.1 - 7.3e-14 51.7 0.0 2.8e-13 49.8 0.0 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.12 KLO20690.1 - 1.9e-11 43.3 0.1 1e-05 24.5 0.0 2.7 2 1 0 2 2 2 2 RmlD substrate binding domain NmrA PF05368.8 KLO20690.1 - 7.7e-08 31.8 0.0 1e-07 31.4 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_4 PF07993.7 KLO20690.1 - 1.1e-05 24.4 0.0 0.0012 17.8 0.0 2.3 1 1 1 2 2 2 1 Male sterility protein Saccharop_dh PF03435.13 KLO20690.1 - 0.00014 20.9 0.0 0.00026 20.0 0.0 1.4 1 1 0 1 1 1 1 Saccharopine dehydrogenase adh_short PF00106.20 KLO20690.1 - 0.0024 17.8 0.0 0.0041 17.0 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase TrkA_N PF02254.13 KLO20690.1 - 0.0076 16.2 0.0 0.015 15.2 0.0 1.6 1 0 0 1 1 1 1 TrkA-N domain Ldh_1_N PF00056.18 KLO20690.1 - 0.13 12.1 0.0 0.26 11.1 0.0 1.5 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain ThiF PF00899.16 KLO20690.1 - 0.15 11.9 0.2 3.6 7.4 0.0 2.3 2 0 0 2 2 2 0 ThiF family Etmic-2 PF06670.6 KLO20692.1 - 0.054 12.2 0.0 0.058 12.1 0.0 1.0 1 0 0 1 1 1 0 Microneme protein Etmic-2 DUF3591 PF12157.3 KLO20695.1 - 3.1e-180 599.4 1.6 3.1e-180 599.4 1.1 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF3591) zf-CCHC_6 PF15288.1 KLO20695.1 - 7.7e-05 22.2 3.0 0.00017 21.2 2.1 1.5 1 0 0 1 1 1 1 Zinc knuckle BCA_ABC_TP_C PF12399.3 KLO20695.1 - 0.1 12.3 1.2 0.25 11.0 0.8 1.6 1 0 0 1 1 1 0 Branched-chain amino acid ATP-binding cassette transporter IncA PF04156.9 KLO20696.1 - 0.26 10.8 4.3 0.12 11.9 1.3 1.6 2 0 0 2 2 2 0 IncA protein HAUS-augmin3 PF14932.1 KLO20696.1 - 0.42 9.7 6.3 0.89 8.6 1.7 2.2 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 3 PI-PLC-X PF00388.14 KLO20697.1 - 0.028 13.8 0.0 0.048 13.0 0.0 1.3 1 0 0 1 1 1 0 Phosphatidylinositol-specific phospholipase C, X domain Hepatitis_core PF00906.15 KLO20697.1 - 0.14 11.7 0.0 0.3 10.7 0.0 1.5 1 0 0 1 1 1 0 Hepatitis core antigen PAP2 PF01569.16 KLO20698.1 - 6e-14 51.8 6.0 8.5e-14 51.3 4.1 1.3 1 0 0 1 1 1 1 PAP2 superfamily DUF212 PF02681.9 KLO20698.1 - 0.00031 20.5 0.3 0.001 18.8 0.0 1.8 2 0 0 2 2 2 1 Divergent PAP2 family Rhodanese PF00581.15 KLO20699.1 - 2e-09 37.7 0.0 3.7e-09 36.9 0.0 1.5 1 1 0 1 1 1 1 Rhodanese-like domain SIR2 PF02146.12 KLO20700.1 - 1.5e-32 112.7 0.0 8.9e-32 110.2 0.0 2.0 1 1 0 1 1 1 1 Sir2 family DUF2117 PF09890.4 KLO20700.1 - 0.085 12.0 0.0 0.17 11.0 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2117) zinc_ribbon_5 PF13719.1 KLO20700.1 - 0.31 10.6 1.5 0.55 9.8 0.0 2.0 2 0 0 2 2 2 0 zinc-ribbon domain EF-hand_6 PF13405.1 KLO20701.1 - 4.3e-12 44.8 1.0 2.8e-05 23.6 0.1 2.5 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.27 KLO20701.1 - 6.9e-12 43.7 7.6 5.5e-06 25.2 0.1 3.4 3 0 0 3 3 3 2 EF hand EF-hand_7 PF13499.1 KLO20701.1 - 7.2e-12 45.2 0.6 0.00011 22.2 0.0 2.3 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.1 KLO20701.1 - 2.1e-07 29.9 6.4 0.00065 18.9 0.3 2.7 3 0 0 3 3 3 2 EF hand EF-hand_8 PF13833.1 KLO20701.1 - 0.00019 21.0 8.7 0.0033 17.0 0.1 3.8 3 1 1 4 4 4 2 EF-hand domain pair EF-hand_9 PF14658.1 KLO20701.1 - 0.073 12.9 0.0 4.8 7.1 0.0 2.5 3 0 0 3 3 3 0 EF-hand domain UPF0154 PF03672.8 KLO20701.1 - 0.087 12.4 0.0 5.6 6.6 0.0 2.3 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0154) LRR_6 PF13516.1 KLO20702.1 - 6.1e-06 25.7 11.6 3.6 7.9 0.1 7.8 9 0 0 9 9 9 1 Leucine Rich repeat LRR_4 PF12799.2 KLO20702.1 - 0.0077 15.8 15.3 12 5.6 0.0 6.2 3 2 4 7 7 7 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 KLO20702.1 - 0.036 13.8 8.8 1.5 8.6 0.5 4.7 3 1 2 5 5 5 0 Leucine rich repeat LRR_1 PF00560.28 KLO20702.1 - 0.2 11.8 4.9 65 4.1 0.3 5.5 6 0 0 6 6 6 0 Leucine Rich Repeat Nucleoplasmin PF03066.10 KLO20702.1 - 1.2 8.6 16.9 2.9 7.4 11.7 1.6 1 0 0 1 1 1 0 Nucleoplasmin TFIIA PF03153.8 KLO20702.1 - 2.1 8.1 11.4 2.7 7.7 7.9 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Cwf_Cwc_15 PF04889.7 KLO20702.1 - 3.2 7.4 12.0 4.7 6.8 8.3 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein PCI PF01399.22 KLO20703.1 - 0.088 13.1 0.0 0.14 12.5 0.0 1.3 1 1 0 1 1 1 0 PCI domain PBP PF01161.15 KLO20704.1 - 2.9e-20 72.6 0.4 5.3e-20 71.7 0.2 1.5 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein F-box-like PF12937.2 KLO20705.1 - 4.5e-05 23.0 1.1 0.0001 21.9 0.7 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 KLO20705.1 - 0.006 16.2 0.4 0.018 14.6 0.3 1.9 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 KLO20706.1 - 0.0017 18.0 0.0 0.005 16.5 0.0 1.9 1 1 0 1 1 1 1 F-box-like FNIP PF05725.7 KLO20706.1 - 0.59 10.1 6.4 1.2 9.1 0.3 4.0 5 0 0 5 5 5 0 FNIP Repeat zf-C2H2 PF00096.21 KLO20708.1 - 3.7e-08 33.2 20.4 0.00012 22.2 1.4 3.7 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-met PF12874.2 KLO20708.1 - 0.00039 20.5 8.2 0.0021 18.1 0.5 3.6 3 0 0 3 3 3 1 Zinc-finger of C2H2 type zf-H2C2_2 PF13465.1 KLO20708.1 - 0.00054 20.1 4.1 0.00054 20.1 2.8 3.5 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_jaz PF12171.3 KLO20708.1 - 0.0039 17.2 0.3 0.0039 17.2 0.2 3.1 3 0 0 3 3 3 1 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.1 KLO20708.1 - 0.022 15.0 1.3 0.022 15.0 0.9 4.4 5 0 0 5 5 5 0 C2H2-type zinc finger Methyltransf_25 PF13649.1 KLO20709.1 - 4.4e-05 23.7 0.1 0.00027 21.2 0.0 2.3 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 KLO20709.1 - 0.00056 19.6 0.0 0.0015 18.2 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain QLQ PF08880.6 KLO20709.1 - 0.16 11.4 0.8 0.6 9.5 0.1 2.2 2 0 0 2 2 2 0 QLQ Methyltransf_25 PF13649.1 KLO20710.1 - 0.00019 21.7 0.0 0.0011 19.2 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain adh_short PF00106.20 KLO20711.1 - 6.6e-27 94.4 0.0 1.1e-26 93.7 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 KLO20711.1 - 4e-13 49.7 0.0 4.9e-13 49.4 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF1776 PF08643.5 KLO20711.1 - 2.1e-09 36.9 0.0 5.9e-08 32.1 0.0 2.1 1 1 0 1 1 1 1 Fungal family of unknown function (DUF1776) KR PF08659.5 KLO20711.1 - 7.7e-07 28.9 0.0 2.5e-06 27.2 0.0 1.7 1 1 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 KLO20711.1 - 0.002 18.1 0.0 0.0045 17.0 0.0 1.7 2 1 0 2 2 2 1 NADH(P)-binding PA28_beta PF02252.13 KLO20712.1 - 2.8e-43 146.9 0.7 4.7e-43 146.2 0.5 1.4 1 0 0 1 1 1 1 Proteasome activator pa28 beta subunit PA28_alpha PF02251.13 KLO20712.1 - 9.4e-08 32.1 0.6 2.1e-07 31.0 0.2 1.7 2 0 0 2 2 2 1 Proteasome activator pa28 alpha subunit FAM180 PF15173.1 KLO20712.1 - 0.036 13.8 0.0 0.31 10.8 0.0 2.3 3 0 0 3 3 3 0 FAM180 family IDEAL PF08858.5 KLO20712.1 - 0.21 11.1 1.6 1.2 8.6 0.1 2.4 2 0 0 2 2 2 0 IDEAL domain WD40 PF00400.27 KLO20713.1 - 3.6e-26 90.0 11.4 8.6e-10 38.1 0.2 5.4 6 0 0 6 6 6 3 WD domain, G-beta repeat CAF1C_H4-bd PF12265.3 KLO20713.1 - 1.1e-18 66.8 0.0 3.5e-18 65.2 0.0 1.9 1 0 0 1 1 1 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex MAPEG PF01124.13 KLO20714.1 - 2.8e-22 78.7 0.3 3.3e-22 78.4 0.2 1.0 1 0 0 1 1 1 1 MAPEG family MAPEG PF01124.13 KLO20715.1 - 1.2e-20 73.4 1.3 1.3e-20 73.2 0.9 1.0 1 0 0 1 1 1 1 MAPEG family UL73_N PF12522.3 KLO20716.1 - 1.7 8.2 16.4 1.3 8.6 2.0 3.4 2 0 0 2 2 2 0 Cytomegalovirus glycoprotein N terminal GARS_A PF01071.14 KLO20720.1 - 9e-80 266.8 0.0 1.6e-79 265.9 0.0 1.4 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain GARS_N PF02844.10 KLO20720.1 - 8.3e-36 122.4 0.1 3.6e-35 120.4 0.0 2.2 2 0 0 2 2 2 1 Phosphoribosylglycinamide synthetase, N domain AIRS_C PF02769.17 KLO20720.1 - 1.4e-33 116.0 0.0 6.3e-33 113.9 0.0 2.1 2 0 0 2 2 2 1 AIR synthase related protein, C-terminal domain GARS_C PF02843.11 KLO20720.1 - 7.8e-28 96.4 2.0 8.5e-28 96.3 0.5 1.7 2 0 0 2 2 2 1 Phosphoribosylglycinamide synthetase, C domain AIRS PF00586.19 KLO20720.1 - 1.5e-17 63.6 0.8 7.4e-17 61.3 0.6 2.3 1 0 0 1 1 1 1 AIR synthase related protein, N-terminal domain ATP-grasp_4 PF13535.1 KLO20720.1 - 1.6e-10 41.0 0.0 2e-09 37.4 0.0 2.6 2 1 0 2 2 2 1 ATP-grasp domain ATPgrasp_Ter PF15632.1 KLO20720.1 - 5.9e-08 31.8 0.0 1.3e-07 30.7 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon CPSase_L_D2 PF02786.12 KLO20720.1 - 5e-07 29.2 0.0 9.6e-07 28.2 0.0 1.5 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Dala_Dala_lig_C PF07478.8 KLO20720.1 - 0.0053 16.1 0.1 0.019 14.3 0.0 2.0 2 0 0 2 2 2 1 D-ala D-ala ligase C-terminus ATP-grasp_3 PF02655.9 KLO20720.1 - 0.0068 16.2 0.0 0.027 14.3 0.0 2.0 2 0 0 2 2 2 1 ATP-grasp domain Ank_2 PF12796.2 KLO20721.1 - 3e-10 40.2 0.1 4.8e-10 39.6 0.1 1.3 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.1 KLO20721.1 - 2.2e-07 30.9 0.1 9.4e-07 28.8 0.0 2.1 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Ank_4 PF13637.1 KLO20721.1 - 1.2e-06 28.8 0.0 2e-06 28.1 0.0 1.4 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 KLO20721.1 - 1.6e-06 27.7 0.0 0.00018 21.4 0.0 2.6 2 0 0 2 2 2 1 Ankyrin repeat Ank PF00023.25 KLO20721.1 - 2.2e-06 27.1 0.3 2.5e-05 23.8 0.0 2.3 2 0 0 2 2 2 1 Ankyrin repeat zf-CCCH_2 PF14608.1 KLO20721.1 - 0.00032 20.5 21.1 0.0036 17.2 6.6 2.5 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type zf-CCCH PF00642.19 KLO20721.1 - 0.016 14.8 14.1 0.17 11.5 1.6 2.5 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) NAD_Gly3P_dh_C PF07479.9 KLO20722.1 - 6.6e-44 149.2 0.3 1e-43 148.6 0.2 1.3 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus NAD_Gly3P_dh_N PF01210.18 KLO20722.1 - 1.1e-32 112.9 0.0 1.8e-32 112.2 0.0 1.3 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus ApbA PF02558.11 KLO20722.1 - 1.3e-07 31.1 0.0 2.5e-07 30.2 0.0 1.5 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA F420_oxidored PF03807.12 KLO20722.1 - 1.7e-06 28.3 0.0 7.1e-06 26.3 0.0 2.0 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.10 KLO20722.1 - 0.0028 17.5 0.0 0.0065 16.3 0.0 1.6 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase TrkA_N PF02254.13 KLO20722.1 - 0.052 13.5 0.0 0.22 11.5 0.0 2.0 2 0 0 2 2 2 0 TrkA-N domain 3HCDH_N PF02737.13 KLO20722.1 - 0.15 11.7 0.0 0.35 10.5 0.0 1.8 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Syntaxin PF00804.20 KLO20723.1 - 1.5e-14 54.0 1.8 1.5e-14 54.0 1.3 2.5 2 0 0 2 2 2 1 Syntaxin SNARE PF05739.14 KLO20723.1 - 2e-14 53.0 0.3 2e-14 53.0 0.2 2.7 3 0 0 3 3 2 1 SNARE domain Sed5p PF11416.3 KLO20723.1 - 0.0037 16.6 0.0 0.0089 15.4 0.0 1.6 1 0 0 1 1 1 1 Integral membrane protein Sed5p Syntaxin-18_N PF10496.4 KLO20723.1 - 0.024 14.4 1.4 0.094 12.5 0.0 2.6 3 0 0 3 3 3 0 SNARE-complex protein Syntaxin-18 N-terminus FlaC_arch PF05377.6 KLO20723.1 - 0.047 13.5 3.4 0.13 12.1 0.1 3.0 2 1 0 2 2 2 0 Flagella accessory protein C (FlaC) Phage_mat-A PF03863.8 KLO20723.1 - 0.093 11.7 0.0 0.12 11.4 0.0 1.3 1 0 0 1 1 1 0 Phage maturation protein DUF1664 PF07889.7 KLO20723.1 - 0.12 12.1 6.2 2.7 7.8 0.3 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) SlyX PF04102.7 KLO20723.1 - 0.14 12.5 7.8 3.8 7.9 0.2 3.1 2 1 0 2 2 2 0 SlyX Peripla_BP_2 PF01497.13 KLO20723.1 - 0.16 11.0 2.2 0.55 9.3 1.2 1.9 1 1 0 2 2 2 0 Periplasmic binding protein Reo_sigmaC PF04582.7 KLO20723.1 - 0.34 10.0 4.5 7 5.7 0.8 2.2 2 0 0 2 2 2 0 Reovirus sigma C capsid protein IncA PF04156.9 KLO20723.1 - 0.66 9.5 10.2 0.31 10.5 0.4 2.4 2 0 0 2 2 2 0 IncA protein AAA_13 PF13166.1 KLO20723.1 - 1.1 7.6 7.5 1.7 7.0 2.2 2.1 2 0 0 2 2 2 0 AAA domain FliD_N PF02465.13 KLO20723.1 - 1.4 9.3 7.0 0.25 11.7 0.3 2.6 2 1 0 2 2 2 0 Flagellar hook-associated protein 2 N-terminus Cluap1 PF10234.4 KLO20723.1 - 1.4 8.0 7.8 0.49 9.5 0.6 2.3 2 1 0 2 2 2 0 Clusterin-associated protein-1 Osmo_CC PF08946.5 KLO20723.1 - 2 8.5 4.8 8.4 6.5 0.3 3.2 3 0 0 3 3 3 0 Osmosensory transporter coiled coil NPV_P10 PF05531.7 KLO20723.1 - 2.4 8.4 9.7 0.66 10.2 0.6 2.8 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Spectrin PF00435.16 KLO20723.1 - 4 7.7 7.9 0.7 10.2 0.1 2.7 3 1 0 3 3 2 0 Spectrin repeat RRM_1 PF00076.17 KLO20724.1 - 1.7e-10 40.3 0.0 3.4e-10 39.4 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 KLO20724.1 - 2.8e-10 40.0 0.0 4.8e-10 39.2 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 KLO20724.1 - 0.024 14.4 0.0 0.043 13.6 0.0 1.3 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Lin-8 PF03353.10 KLO20724.1 - 2 7.6 8.5 0.34 10.1 3.1 1.6 1 1 1 2 2 2 0 Ras-mediated vulval-induction antagonist CPSF100_C PF13299.1 KLO20724.1 - 8.9 6.4 10.6 0.71 10.0 2.2 2.1 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal Pex2_Pex12 PF04757.9 KLO20727.1 - 0.17 11.2 0.9 0.28 10.5 0.6 1.3 1 0 0 1 1 1 0 Pex2 / Pex12 amino terminal region AMP-binding PF00501.23 KLO20729.1 - 9.2e-88 294.4 0.0 1.2e-87 294.0 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 KLO20729.1 - 4.7e-12 46.6 0.2 4.7e-12 46.6 0.1 2.3 3 0 0 3 3 3 1 AMP-binding enzyme C-terminal domain Med7 PF05983.6 KLO20730.1 - 1.6e-28 99.5 0.1 2.2e-28 99.1 0.1 1.2 1 0 0 1 1 1 1 MED7 protein P34-Arc PF04045.9 KLO20731.1 - 6.1e-104 346.5 0.1 7.3e-104 346.3 0.0 1.0 1 0 0 1 1 1 1 Arp2/3 complex, 34 kD subunit p34-Arc PCI PF01399.22 KLO20732.1 - 2e-16 60.1 0.0 9e-16 58.0 0.0 2.1 2 0 0 2 2 2 1 PCI domain Rnk_N PF14760.1 KLO20732.1 - 0.018 15.0 0.3 8 6.6 0.0 2.6 2 0 0 2 2 2 0 Rnk N-terminus Drc1-Sld2 PF11719.3 KLO20733.1 - 1.5e-15 57.2 11.7 1.5e-15 57.2 8.1 2.7 1 1 2 3 3 3 1 DNA replication and checkpoint protein BLVR PF06375.6 KLO20733.1 - 0.72 9.6 8.9 0.056 13.2 0.5 2.6 2 0 0 2 2 2 0 Bovine leukaemia virus receptor (BLVR) Pkinase PF00069.20 KLO20736.1 - 1.4e-50 171.8 0.0 1.8e-50 171.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 KLO20736.1 - 4.7e-31 107.7 0.0 6e-31 107.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 KLO20736.1 - 0.015 14.2 0.0 0.026 13.4 0.0 1.4 1 0 0 1 1 1 0 Kinase-like FHA PF00498.21 KLO20736.1 - 0.031 14.4 0.1 0.098 12.7 0.0 1.9 1 1 0 1 1 1 0 FHA domain Esterase PF00756.15 KLO20737.1 - 3.6e-40 137.9 0.0 4.3e-40 137.7 0.0 1.0 1 0 0 1 1 1 1 Putative esterase Abhydrolase_5 PF12695.2 KLO20737.1 - 2.3e-05 24.1 0.1 3.1e-05 23.7 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 KLO20737.1 - 0.0017 17.5 0.2 0.0025 17.0 0.1 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family Chlorophyllase2 PF12740.2 KLO20737.1 - 0.0057 15.5 0.0 0.0076 15.1 0.0 1.3 1 0 0 1 1 1 1 Chlorophyllase enzyme PGAP1 PF07819.8 KLO20738.1 - 2e-09 37.3 0.1 4.3e-09 36.3 0.0 1.5 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_5 PF12695.2 KLO20738.1 - 1.8e-05 24.4 0.0 3.9e-05 23.4 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 KLO20738.1 - 2.3e-05 24.3 0.4 0.00033 20.6 0.0 2.6 1 1 1 2 2 2 1 Alpha/beta hydrolase family Lipase_3 PF01764.20 KLO20738.1 - 0.00022 20.8 0.0 0.00038 20.0 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_1 PF00561.15 KLO20738.1 - 0.0021 17.6 0.0 0.0034 16.9 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF676 PF05057.9 KLO20738.1 - 0.0037 16.5 0.1 0.0083 15.4 0.0 1.6 2 0 0 2 2 2 1 Putative serine esterase (DUF676) DUF915 PF06028.6 KLO20738.1 - 0.011 14.7 0.0 0.025 13.6 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) LCAT PF02450.10 KLO20738.1 - 0.013 14.4 0.0 0.026 13.5 0.0 1.4 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase UPF0227 PF05728.7 KLO20738.1 - 0.15 11.7 0.0 0.28 10.8 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) Filament_head PF04732.9 KLO20738.1 - 5.6 7.7 14.7 1.8 9.3 1.7 3.0 2 0 0 2 2 2 0 Intermediate filament head (DNA binding) region Kelch_3 PF13415.1 KLO20739.1 - 7.7e-40 134.1 17.9 6.2e-12 45.3 0.0 7.0 6 1 0 6 6 6 5 Galactose oxidase, central domain Kelch_5 PF13854.1 KLO20739.1 - 6e-36 121.8 5.2 1.8e-07 30.9 0.0 6.2 6 0 0 6 6 6 6 Kelch motif Kelch_4 PF13418.1 KLO20739.1 - 8.8e-35 118.2 13.6 7.3e-12 44.8 0.1 6.5 6 1 0 6 6 6 4 Galactose oxidase, central domain Kelch_6 PF13964.1 KLO20739.1 - 9.2e-28 95.2 9.0 1e-08 34.9 0.1 6.4 3 2 3 6 6 6 5 Kelch motif Kelch_1 PF01344.20 KLO20739.1 - 1.7e-22 78.6 10.1 1.5e-08 34.0 0.1 5.5 6 0 0 6 6 6 3 Kelch motif Kelch_2 PF07646.10 KLO20739.1 - 1.8e-21 75.0 12.0 4.4e-08 32.5 0.3 6.5 6 1 0 6 6 6 4 Kelch motif RAG2 PF03089.9 KLO20739.1 - 0.0007 18.4 1.2 0.27 9.9 0.0 3.9 3 1 1 5 5 5 1 Recombination activating protein 2 DUF1668 PF07893.8 KLO20739.1 - 0.017 14.2 0.1 0.039 13.0 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1668) Kelch_3 PF13415.1 KLO20740.1 - 1.9e-36 123.4 12.8 3.3e-09 36.6 0.1 6.8 6 0 0 6 6 6 5 Galactose oxidase, central domain Kelch_4 PF13418.1 KLO20740.1 - 2.7e-35 119.8 15.4 9.1e-10 38.1 1.2 6.5 5 1 1 6 6 6 5 Galactose oxidase, central domain Kelch_5 PF13854.1 KLO20740.1 - 3.2e-32 109.9 11.4 1.3e-07 31.3 0.0 6.4 6 0 0 6 6 6 6 Kelch motif Kelch_1 PF01344.20 KLO20740.1 - 2.2e-29 100.7 2.1 3.3e-10 39.3 1.3 6.1 6 0 0 6 6 6 4 Kelch motif Kelch_6 PF13964.1 KLO20740.1 - 7.5e-26 89.1 9.6 6.2e-10 38.8 1.0 6.4 4 2 2 6 6 6 6 Kelch motif Kelch_2 PF07646.10 KLO20740.1 - 6e-22 76.5 8.4 1.6e-07 30.8 0.5 6.5 6 0 0 6 6 6 5 Kelch motif WEMBL PF05701.6 KLO20740.1 - 0.00029 19.4 25.8 0.00029 19.4 17.9 3.6 1 1 1 2 2 2 1 Weak chloroplast movement under blue light IncA PF04156.9 KLO20740.1 - 0.0036 16.9 8.3 0.0036 16.9 5.8 6.7 1 1 4 6 6 6 2 IncA protein RAG2 PF03089.9 KLO20740.1 - 0.069 11.8 0.2 2.7 6.6 0.0 3.4 3 1 1 4 4 4 0 Recombination activating protein 2 Reo_sigmaC PF04582.7 KLO20740.1 - 4.3 6.4 32.6 0.35 10.0 1.2 5.4 1 1 2 6 6 6 0 Reovirus sigma C capsid protein S1 PF00575.18 KLO20741.1 - 7.9e-56 186.0 31.8 1.5e-11 44.2 0.5 10.2 10 0 0 10 10 10 7 S1 RNA binding domain TPR_16 PF13432.1 KLO20741.1 - 6.5e-05 23.4 0.0 1 10.0 0.0 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.1 KLO20741.1 - 0.00049 20.3 0.0 0.43 10.9 0.0 3.1 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.1 KLO20741.1 - 0.00099 19.5 0.0 24 5.9 0.0 4.8 4 1 1 5 5 5 0 Tetratricopeptide repeat TPR_12 PF13424.1 KLO20741.1 - 0.0019 18.1 1.3 0.88 9.5 0.0 3.5 3 1 1 4 4 4 1 Tetratricopeptide repeat Suf PF05843.9 KLO20741.1 - 0.0051 16.5 0.1 0.0051 16.5 0.1 5.0 2 1 1 5 5 5 2 Suppressor of forked protein (Suf) EXOSC1 PF10447.4 KLO20741.1 - 0.013 15.4 7.6 0.043 13.7 0.5 4.4 4 0 0 4 4 4 0 Exosome component EXOSC1/CSL4 TPR_17 PF13431.1 KLO20741.1 - 0.15 12.3 0.1 5.7 7.4 0.0 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat zf-met PF12874.2 KLO20742.1 - 2.7e-06 27.3 0.8 2.7e-06 27.3 0.6 2.5 3 0 0 3 3 3 1 Zinc-finger of C2H2 type MMR_HSR1 PF01926.18 KLO20743.1 - 2.3e-17 62.9 0.0 9.8e-15 54.5 0.0 2.6 2 1 0 2 2 2 2 50S ribosome-binding GTPase FeoB_N PF02421.13 KLO20743.1 - 1.2e-05 24.6 0.0 9.1e-05 21.7 0.0 2.2 2 0 0 2 2 2 1 Ferrous iron transport protein B DUF258 PF03193.11 KLO20743.1 - 0.00017 20.7 0.0 0.00034 19.8 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AIG1 PF04548.11 KLO20743.1 - 0.00025 20.2 0.1 0.00091 18.3 0.0 1.9 2 0 0 2 2 2 1 AIG1 family Dynamin_N PF00350.18 KLO20743.1 - 0.0085 15.9 0.1 0.023 14.5 0.0 1.7 1 0 0 1 1 1 1 Dynamin family Miro PF08477.8 KLO20743.1 - 0.011 16.2 0.2 0.049 14.1 0.0 2.1 2 0 0 2 2 2 0 Miro-like protein Cellulase PF00150.13 KLO20744.1 - 4.5e-44 150.7 0.0 5.6e-44 150.4 0.0 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) TOBE_3 PF12857.2 KLO20744.1 - 0.03 14.1 0.1 6.4 6.7 0.0 2.4 2 0 0 2 2 2 0 TOBE-like domain CBM_1 PF00734.13 KLO20744.1 - 0.54 9.9 2.7 1.4 8.6 1.9 1.7 1 0 0 1 1 1 0 Fungal cellulose binding domain Complex1_LYR PF05347.10 KLO20745.1 - 6.1e-06 25.9 5.0 2.2e-05 24.1 3.2 2.0 1 1 1 2 2 2 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 KLO20745.1 - 0.00061 19.9 2.8 0.0015 18.7 2.0 1.6 1 0 0 1 1 1 1 Complex1_LYR-like Sec8_exocyst PF04048.9 KLO20746.1 - 5.5e-34 116.8 1.4 1.1e-33 115.8 0.3 2.0 2 0 0 2 2 2 1 Sec8 exocyst complex component specific domain DUF2450 PF10475.4 KLO20746.1 - 1.5e-07 30.6 0.7 3.6e-07 29.3 0.5 1.6 1 0 0 1 1 1 1 Protein of unknown function N-terminal domain (DUF2450) DUF2305 PF10230.4 KLO20747.1 - 6.7e-46 156.8 0.0 7.9e-46 156.6 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2305) Abhydrolase_6 PF12697.2 KLO20747.1 - 5.1e-11 42.8 0.0 6.4e-11 42.5 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 KLO20747.1 - 3.7e-06 26.7 0.0 9.7e-06 25.3 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Ser_hydrolase PF06821.8 KLO20747.1 - 0.067 12.7 0.1 0.21 11.1 0.0 1.8 2 0 0 2 2 2 0 Serine hydrolase DUF900 PF05990.7 KLO20747.1 - 0.098 11.9 0.0 0.22 10.8 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) Pkinase_Tyr PF07714.12 KLO20748.1 - 1.5e-51 174.9 0.0 5e-51 173.2 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 KLO20748.1 - 3.3e-47 160.8 0.0 5e-47 160.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Fve PF09259.6 KLO20748.1 - 2.7e-25 88.4 0.0 7.3e-25 87.0 0.0 1.7 2 0 0 2 2 2 1 Fungal immunomodulatory protein Fve RIO1 PF01163.17 KLO20748.1 - 2.4e-05 23.7 0.0 4.6e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 RIO1 family HTH_24 PF13412.1 KLO20748.1 - 0.039 13.3 0.9 1.9 7.9 0.1 3.0 3 0 0 3 3 3 0 Winged helix-turn-helix DNA-binding SNF2_N PF00176.18 KLO20749.1 - 7.2e-73 244.9 0.2 1.4e-48 165.2 0.0 2.8 2 1 0 2 2 2 2 SNF2 family N-terminal domain Helicase_C PF00271.26 KLO20749.1 - 6e-10 38.8 0.0 1.2e-09 37.8 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-RING_5 PF14634.1 KLO20749.1 - 0.0027 17.3 6.0 0.0064 16.1 4.2 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.20 KLO20749.1 - 0.44 10.2 7.0 1.1 8.9 4.9 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) dsrm PF00035.20 KLO20751.1 - 2.3e-10 40.8 0.3 4.1e-10 40.1 0.2 1.4 1 0 0 1 1 1 1 Double-stranded RNA binding motif Ribonucleas_3_3 PF14622.1 KLO20751.1 - 1.1e-09 38.2 0.0 1.7e-09 37.6 0.0 1.3 1 0 0 1 1 1 1 Ribonuclease-III-like Ribonuclease_3 PF00636.21 KLO20751.1 - 0.00015 22.1 0.1 0.00034 21.0 0.1 1.7 1 1 0 1 1 1 1 Ribonuclease III domain SNF2_N PF00176.18 KLO20752.1 - 1.7e-63 214.2 1.1 2.4e-63 213.7 0.8 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain HDA2-3 PF11496.3 KLO20752.1 - 4.1e-19 68.5 1.5 7.5e-19 67.6 1.1 1.4 1 0 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 Helicase_C PF00271.26 KLO20752.1 - 7.2e-16 57.8 0.0 2.1e-15 56.3 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Chromo PF00385.19 KLO20752.1 - 3.6e-06 26.5 5.4 0.0039 16.8 0.0 3.8 4 0 0 4 4 4 2 Chromo (CHRromatin Organisation MOdifier) domain zf-PHD-like PF15446.1 KLO20752.1 - 0.00021 20.6 14.3 0.0016 17.7 0.1 3.1 2 1 0 2 2 2 2 PHD/FYVE-zinc-finger like domain Zn_clus PF00172.13 KLO20753.1 - 9.3e-08 31.8 11.1 1.7e-07 31.0 7.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 KLO20753.1 - 2e-06 26.9 0.0 5.4e-06 25.4 0.0 1.7 1 0 0 1 1 1 1 Fungal specific transcription factor domain ABC_membrane PF00664.18 KLO20754.1 - 5.4e-66 222.8 32.8 1.2e-34 120.0 4.9 2.9 2 1 1 3 3 3 2 ABC transporter transmembrane region ABC_tran PF00005.22 KLO20754.1 - 2.3e-55 186.6 0.0 4.9e-31 107.8 0.1 2.5 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 KLO20754.1 - 4.6e-08 33.3 1.7 0.0048 16.9 0.1 4.2 2 2 1 3 3 3 2 AAA domain SMC_N PF02463.14 KLO20754.1 - 2e-06 27.2 4.9 0.0043 16.3 0.8 3.6 3 1 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 KLO20754.1 - 7.5e-06 25.3 0.7 0.064 12.7 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_25 PF13481.1 KLO20754.1 - 1e-05 25.0 0.0 0.018 14.4 0.0 2.5 2 0 0 2 2 2 2 AAA domain MMR_HSR1 PF01926.18 KLO20754.1 - 1.8e-05 24.6 1.7 0.17 11.8 0.1 3.3 3 0 0 3 3 3 2 50S ribosome-binding GTPase DUF258 PF03193.11 KLO20754.1 - 0.0001 21.5 2.2 0.047 12.8 0.0 2.7 3 0 0 3 3 3 2 Protein of unknown function, DUF258 AAA_16 PF13191.1 KLO20754.1 - 0.00029 20.8 1.3 0.076 12.9 0.0 3.0 2 1 0 2 2 2 1 AAA ATPase domain AAA_23 PF13476.1 KLO20754.1 - 0.0007 19.9 0.1 0.19 12.0 0.1 2.4 2 0 0 2 2 2 1 AAA domain Miro PF08477.8 KLO20754.1 - 0.00093 19.6 1.9 0.61 10.6 0.2 2.6 2 0 0 2 2 2 2 Miro-like protein MobB PF03205.9 KLO20754.1 - 0.0018 18.0 0.7 0.28 10.8 0.0 2.5 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_10 PF12846.2 KLO20754.1 - 0.0056 16.1 0.1 0.91 8.8 0.0 2.5 2 0 0 2 2 2 1 AAA-like domain ATP_bind_1 PF03029.12 KLO20754.1 - 0.0056 16.2 2.7 13 5.2 0.1 3.3 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein AAA_17 PF13207.1 KLO20754.1 - 0.0059 17.4 0.0 6.7 7.5 0.0 3.0 2 0 0 2 2 2 0 AAA domain Dynamin_N PF00350.18 KLO20754.1 - 0.0085 15.9 3.7 0.62 9.8 0.2 2.5 2 0 0 2 2 2 1 Dynamin family Zeta_toxin PF06414.7 KLO20754.1 - 0.013 14.5 0.6 4.4 6.3 0.1 2.3 2 0 0 2 2 2 0 Zeta toxin NACHT PF05729.7 KLO20754.1 - 0.033 13.8 0.7 0.45 10.1 0.0 2.4 2 0 0 2 2 2 0 NACHT domain ArgK PF03308.11 KLO20754.1 - 0.04 12.7 0.4 6.2 5.5 0.0 2.3 2 0 0 2 2 2 0 ArgK protein FtsK_SpoIIIE PF01580.13 KLO20754.1 - 0.051 13.0 0.4 7.6 5.9 0.0 3.2 3 0 0 3 3 3 0 FtsK/SpoIIIE family AAA_22 PF13401.1 KLO20754.1 - 0.055 13.6 3.6 7.7 6.6 0.1 3.3 2 1 0 2 2 2 0 AAA domain AAA_18 PF13238.1 KLO20754.1 - 0.06 13.6 0.2 15 5.9 0.0 2.9 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.17 KLO20754.1 - 0.061 13.4 0.2 19 5.5 0.0 3.4 3 0 0 3 3 3 0 RNA helicase UPF0079 PF02367.12 KLO20754.1 - 0.093 12.3 2.1 0.28 10.8 0.0 2.5 3 0 0 3 3 3 0 Uncharacterised P-loop hydrolase UPF0079 AAA_33 PF13671.1 KLO20754.1 - 0.093 12.6 2.2 0.44 10.4 0.2 2.8 3 0 0 3 3 3 0 AAA domain DUF4349 PF14257.1 KLO20754.1 - 0.099 11.8 0.8 0.23 10.6 0.5 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4349) Arch_ATPase PF01637.13 KLO20754.1 - 0.21 11.2 1.0 2.6 7.6 0.0 2.8 3 0 0 3 3 3 0 Archaeal ATPase AAA_13 PF13166.1 KLO20754.1 - 0.26 9.7 0.1 0.45 8.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain cobW PF02492.14 KLO20754.1 - 0.33 10.3 2.4 1.6 8.1 0.1 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_30 PF13604.1 KLO20754.1 - 0.83 9.1 3.2 8.9 5.8 0.1 2.8 3 0 0 3 3 3 0 AAA domain DUF87 PF01935.12 KLO20754.1 - 1.1 9.0 4.0 0.74 9.5 0.2 2.5 3 0 0 3 3 3 0 Domain of unknown function DUF87 Amidase PF01425.16 KLO20755.1 - 3.7e-85 286.4 0.0 4.3e-85 286.1 0.0 1.0 1 0 0 1 1 1 1 Amidase TB2_DP1_HVA22 PF03134.14 KLO20756.1 - 1.5e-20 72.7 6.7 2.1e-20 72.2 4.7 1.2 1 0 0 1 1 1 1 TB2/DP1, HVA22 family GtrA PF04138.9 KLO20756.1 - 0.0013 18.6 3.7 0.002 18.0 2.5 1.4 1 1 0 1 1 1 1 GtrA-like protein DUF2052 PF09747.4 KLO20757.1 - 1.8e-07 31.2 16.0 3.3e-07 30.4 11.1 1.5 1 1 0 1 1 1 1 Coiled-coil domain containing protein (DUF2052) DnaG_DnaB_bind PF08278.6 KLO20757.1 - 0.052 13.7 0.8 0.1 12.8 0.5 1.4 1 0 0 1 1 1 0 DNA primase DnaG DnaB-binding DUF3482 PF11981.3 KLO20757.1 - 0.17 11.0 3.8 1.3 8.1 0.3 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3482) Sec3_C PF09763.4 KLO20758.1 - 6.9e-173 576.4 1.1 1.1e-172 575.8 0.8 1.2 1 0 0 1 1 1 1 Exocyst complex component Sec3 Sec3-PIP2_bind PF15277.1 KLO20758.1 - 6.5e-20 70.8 0.0 1.4e-19 69.7 0.0 1.6 1 0 0 1 1 1 1 Exocyst complex component SEC3 N-terminal PIP2 binding PH Vps52 PF04129.7 KLO20758.1 - 0.00085 17.9 2.1 0.0017 16.9 1.5 1.4 1 0 0 1 1 1 1 Vps52 / Sac2 family CRISPR_Cas2 PF09827.4 KLO20758.1 - 0.065 13.3 0.2 0.26 11.4 0.2 2.1 1 0 0 1 1 1 0 CRISPR associated protein Cas2 SNAPc_SNAP43 PF09808.4 KLO20759.1 - 3.3e-05 23.6 0.0 4.6e-05 23.1 0.0 1.2 1 0 0 1 1 1 1 Small nuclear RNA activating complex (SNAPc), subunit SNAP43 His_Phos_2 PF00328.17 KLO20760.1 - 2.2e-24 86.4 0.0 8.1e-13 48.4 0.0 2.1 1 1 0 2 2 2 2 Histidine phosphatase superfamily (branch 2) SE PF08491.5 KLO20761.1 - 3.3e-90 301.6 0.0 4.4e-90 301.2 0.0 1.1 1 0 0 1 1 1 1 Squalene epoxidase DAO PF01266.19 KLO20761.1 - 2.2e-09 36.7 0.1 0.0012 17.7 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 KLO20761.1 - 1.3e-08 34.3 0.4 8e-05 21.8 0.1 2.9 2 1 0 2 2 2 2 FAD binding domain FAD_binding_2 PF00890.19 KLO20761.1 - 1.7e-05 23.8 3.5 0.013 14.4 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain GIDA PF01134.17 KLO20761.1 - 0.00021 20.3 0.8 0.055 12.3 0.0 2.1 2 0 0 2 2 2 2 Glucose inhibited division protein A Lycopene_cycl PF05834.7 KLO20761.1 - 0.00088 18.2 0.0 0.059 12.2 0.0 2.4 3 0 0 3 3 3 1 Lycopene cyclase protein Trp_halogenase PF04820.9 KLO20761.1 - 0.0015 17.2 0.6 0.28 9.7 0.1 2.2 2 0 0 2 2 2 2 Tryptophan halogenase Pyr_redox_2 PF07992.9 KLO20761.1 - 0.0022 17.9 0.5 0.01 15.7 0.3 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 KLO20761.1 - 0.0057 16.6 0.0 0.015 15.3 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain GMC_oxred_N PF00732.14 KLO20761.1 - 0.019 14.1 0.4 0.36 9.9 0.1 2.1 2 0 0 2 2 2 0 GMC oxidoreductase NAD_binding_9 PF13454.1 KLO20761.1 - 0.11 12.3 0.1 0.74 9.5 0.0 2.1 2 0 0 2 2 2 0 FAD-NAD(P)-binding Pyr_redox PF00070.22 KLO20761.1 - 0.13 12.6 0.1 0.63 10.4 0.0 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Ima1_N PF09779.4 KLO20762.1 - 1.3e-23 83.8 2.0 5.2e-23 81.9 1.4 1.9 1 1 0 1 1 1 1 Ima1 N-terminal domain SOBP PF15279.1 KLO20763.1 - 0.033 14.5 15.0 0.043 14.2 10.4 1.3 1 0 0 1 1 1 0 Sine oculis-binding protein TFIIA PF03153.8 KLO20763.1 - 0.064 13.1 9.6 0.079 12.8 6.6 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit CytochromB561_N PF09786.4 KLO20763.1 - 0.31 9.4 22.8 0.35 9.2 15.8 1.1 1 0 0 1 1 1 0 Cytochrome B561, N terminal DUF572 PF04502.8 KLO20763.1 - 8.6 5.4 19.6 15 4.7 13.6 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF572) Hepar_II_III PF07940.8 KLO20764.1 - 1.8e-08 34.3 0.8 1.8e-08 34.3 0.5 1.7 2 0 0 2 2 2 1 Heparinase II/III-like protein ETRAMP PF09716.5 KLO20764.1 - 0.022 14.7 0.1 0.05 13.5 0.1 1.6 1 0 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) TatD_DNase PF01026.16 KLO20765.1 - 1.1e-51 175.5 0.0 1.4e-51 175.1 0.0 1.1 1 0 0 1 1 1 1 TatD related DNase Thiolase_N PF00108.18 KLO20766.1 - 6.6e-73 244.9 0.5 1.4e-72 243.8 0.0 1.7 2 0 0 2 2 2 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 KLO20766.1 - 1.5e-46 156.7 0.6 2.9e-46 155.8 0.4 1.5 1 0 0 1 1 1 1 Thiolase, C-terminal domain ACP_syn_III PF08545.5 KLO20766.1 - 3.6e-05 23.3 2.6 0.0021 17.6 0.1 3.1 3 0 0 3 3 3 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III ACP_syn_III_C PF08541.5 KLO20766.1 - 8.5e-05 22.4 0.0 0.00021 21.2 0.0 1.7 1 0 0 1 1 1 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal ketoacyl-synt PF00109.21 KLO20766.1 - 0.002 17.6 0.8 0.0058 16.1 0.3 2.1 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Glyco_transf_21 PF13506.1 KLO20767.1 - 3.2e-24 85.1 0.2 2.6e-17 62.6 0.1 3.1 2 1 0 2 2 2 2 Glycosyl transferase family 21 Glyco_tranf_2_3 PF13641.1 KLO20767.1 - 1.1e-16 61.3 0.0 1.5e-16 60.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.21 KLO20767.1 - 2.5e-05 24.0 0.0 4.2e-05 23.2 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 2 DUF368 PF04018.8 KLO20768.1 - 0.37 9.9 10.3 0.49 9.5 6.8 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF368) p450 PF00067.17 KLO20769.1 - 5.1e-65 219.7 0.2 1.1e-41 142.8 0.0 2.0 2 0 0 2 2 2 2 Cytochrome P450 DUF2414 PF10309.4 KLO20770.1 - 2e-08 33.8 0.0 3e-08 33.2 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2414) RNA_bind PF08675.6 KLO20770.1 - 3.6e-06 26.8 0.0 6.2e-06 26.1 0.0 1.3 1 0 0 1 1 1 1 RNA binding domain DUF2404 PF10296.4 KLO20772.1 - 3.5e-29 100.7 0.1 6.5e-29 99.9 0.1 1.5 1 0 0 1 1 1 1 Putative integral membrane protein conserved region (DUF2404) ECM11 PF15463.1 KLO20774.1 - 0.15 12.3 0.8 0.47 10.7 0.5 1.8 1 1 0 1 1 1 0 Extracellular mutant protein 11 WD40 PF00400.27 KLO20775.1 - 3.7e-53 175.5 22.9 6.7e-09 35.3 0.3 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat eIF2A PF08662.6 KLO20775.1 - 0.0023 17.6 0.0 0.35 10.5 0.0 2.4 1 1 2 3 3 3 3 Eukaryotic translation initiation factor eIF2A dsrm PF00035.20 KLO20777.1 - 2.1e-07 31.4 0.0 2.4e-07 31.2 0.0 1.2 1 0 0 1 1 1 1 Double-stranded RNA binding motif dsrm PF00035.20 KLO20779.1 - 2.8e-11 43.8 0.0 3.2e-11 43.6 0.0 1.1 1 0 0 1 1 1 1 Double-stranded RNA binding motif DND1_DSRM PF14709.1 KLO20779.1 - 0.068 13.4 0.0 0.097 12.9 0.0 1.3 1 0 0 1 1 1 0 double strand RNA binding domain from DEAD END PROTEIN 1 Rsm22 PF09243.5 KLO20780.1 - 6.9e-43 146.6 0.0 2.7e-42 144.7 0.0 1.8 1 1 0 1 1 1 1 Mitochondrial small ribosomal subunit Rsm22 UCH PF00443.24 KLO20781.1 - 4.2e-27 94.9 0.0 5.6e-27 94.5 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.14 KLO20781.1 - 3.5e-10 39.8 0.1 6.9e-10 38.9 0.0 1.4 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein MRP-L28 PF09812.4 KLO20782.1 - 1.7e-09 37.7 6.6 1.5e-07 31.3 1.5 2.4 1 1 1 2 2 2 2 Mitochondrial ribosomal protein L28 DUF4375 PF14300.1 KLO20782.1 - 0.12 12.3 0.1 0.17 11.8 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4375) PCI PF01399.22 KLO20783.1 - 1.4e-20 73.5 0.4 4.4e-20 71.9 0.3 1.9 1 0 0 1 1 1 1 PCI domain PCI_Csn8 PF10075.4 KLO20783.1 - 1.1e-09 38.2 0.3 2.5e-09 37.0 0.2 1.7 1 0 0 1 1 1 1 COP9 signalosome, subunit CSN8 FeoC PF09012.5 KLO20783.1 - 0.024 14.3 0.0 0.056 13.1 0.0 1.6 1 0 0 1 1 1 0 FeoC like transcriptional regulator APC8 PF04049.8 KLO20783.1 - 0.052 13.2 1.6 0.056 13.1 0.1 1.8 2 0 0 2 2 2 0 Anaphase promoting complex subunit 8 / Cdc23 PIP5K PF01504.13 KLO20784.1 - 1.6e-62 210.9 0.0 2.7e-62 210.1 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase Cpn60_TCP1 PF00118.19 KLO20784.1 - 6e-27 94.4 0.0 8.9e-27 93.8 0.0 1.1 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family FYVE PF01363.16 KLO20784.1 - 9.6e-18 63.8 10.2 9.7e-18 63.8 5.6 2.0 2 0 0 2 2 2 1 FYVE zinc finger LTV PF04180.9 KLO20785.1 - 4.2e-70 237.3 34.1 3.3e-64 217.9 14.8 2.2 2 0 0 2 2 2 2 Low temperature viability protein F-box-like PF12937.2 KLO20790.1 - 0.00057 19.5 1.0 0.0022 17.6 0.2 2.2 2 0 0 2 2 2 1 F-box-like