# --- full sequence ---- --- best 1 domain ---- --- domain number estimation ---- # target name accession query name accession E-value score bias E-value score bias exp reg clu ov env dom rep inc description of target #------------------- ---------- -------------------- ---------- --------- ------ ----- --------- ------ ----- --- --- --- --- --- --- --- --- --------------------- Pec_lyase_C PF00544.19 KFX85682.1 - 2e-29 102.7 5.9 1.3e-28 100.0 5.9 2.0 1 1 0 1 1 1 1 Pectate lyase Dicty_CAR PF05462.11 KFX85683.1 - 2.8e-07 30.0 2.2 2.8e-07 30.0 2.2 1.9 2 0 0 2 2 2 1 Slime mold cyclic AMP receptor Git3 PF11710.8 KFX85683.1 - 2.2e-06 27.6 4.8 3.7e-06 26.9 3.9 1.8 2 0 0 2 2 2 1 G protein-coupled glucose receptor regulating Gpa2 7tm_1 PF00001.21 KFX85683.1 - 5.1e-06 26.0 0.0 8.2e-06 25.3 0.0 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Frizzled PF01534.17 KFX85683.1 - 0.32 10.0 4.9 0.14 11.1 1.5 1.8 2 0 0 2 2 2 0 Frizzled/Smoothened family membrane region ABC_export PF16962.5 KFX85684.1 - 0.014 13.9 0.2 0.014 13.9 0.2 2.1 2 1 0 3 3 3 0 Putative ABC exporter STE3 PF02076.15 KFX85684.1 - 0.028 13.6 0.1 0.028 13.6 0.1 2.5 4 0 0 4 4 4 0 Pheromone A receptor LrgA PF03788.14 KFX85684.1 - 0.056 13.4 1.7 0.19 11.7 1.7 1.9 1 0 0 1 1 1 0 LrgA family Cu-oxidase_3 PF07732.15 KFX85685.1 - 1.9e-36 124.7 0.8 9.2e-36 122.5 0.0 2.5 3 0 0 3 3 3 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 KFX85685.1 - 7.9e-24 83.9 5.9 1.7e-19 69.9 0.1 4.2 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase PF00394.22 KFX85685.1 - 5.9e-13 49.2 0.0 1.4e-12 48.0 0.0 1.7 1 0 0 1 1 1 1 Multicopper oxidase Arm-DNA-bind_3 PF13356.6 KFX85685.1 - 0.2 12.1 0.0 0.6 10.5 0.0 1.8 1 0 0 1 1 1 0 Arm DNA-binding domain HTH_51 PF18558.1 KFX85686.1 - 2.8e-23 81.6 0.0 5.5e-23 80.7 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain Methyltransf_12 PF08242.12 KFX85686.1 - 1.9e-14 54.2 0.0 4.5e-14 53.0 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KFX85686.1 - 1.6e-10 41.1 0.0 3.2e-08 33.6 0.0 2.2 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_25 PF13649.6 KFX85686.1 - 6.5e-10 39.6 0.0 2.1e-09 38.0 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KFX85686.1 - 5.8e-08 33.3 0.0 1.8e-06 28.5 0.0 2.8 3 0 0 3 3 3 1 Methyltransferase domain PP-binding PF00550.25 KFX85686.1 - 2.9e-06 27.5 0.0 6.3e-06 26.5 0.0 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site Methyltransf_33 PF10017.9 KFX85686.1 - 0.033 13.3 0.0 0.47 9.6 0.0 2.1 2 0 0 2 2 2 0 Histidine-specific methyltransferase, SAM-dependent Methyltransf_31 PF13847.6 KFX85686.1 - 0.062 13.1 0.0 0.12 12.1 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Ubie_methyltran PF01209.18 KFX85686.1 - 0.063 12.6 0.0 0.14 11.4 0.0 1.5 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family CUE PF02845.16 KFX85696.1 - 9.4e-12 44.4 0.0 1.3e-11 44.0 0.0 1.2 1 0 0 1 1 1 1 CUE domain UBA PF00627.31 KFX85696.1 - 0.00021 21.1 0.0 0.00035 20.4 0.0 1.3 1 0 0 1 1 1 1 UBA/TS-N domain DUF1296 PF06972.11 KFX85696.1 - 0.0077 16.3 0.2 0.049 13.8 0.0 2.0 1 1 1 2 2 2 1 Protein of unknown function (DUF1296) UBA_4 PF14555.6 KFX85696.1 - 0.027 14.3 0.0 0.046 13.6 0.0 1.3 1 0 0 1 1 1 0 UBA-like domain FoP_duplication PF13865.6 KFX85696.1 - 5.5 7.6 25.3 8 7.1 8.8 2.4 2 0 0 2 2 2 0 C-terminal duplication domain of Friend of PRMT1 AT_hook PF02178.19 KFX85699.1 - 0.042 13.7 2.7 0.14 12.2 2.7 2.0 1 0 0 1 1 1 0 AT hook motif zf-C2H2 PF00096.26 KFX85708.1 - 2.2e-10 40.4 9.2 0.0036 17.7 0.2 3.9 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFX85708.1 - 9.6e-06 26.0 13.0 0.22 12.5 0.7 3.8 3 0 0 3 3 3 3 C2H2-type zinc finger zf-met PF12874.7 KFX85708.1 - 0.00011 22.5 10.3 0.21 12.0 0.0 4.5 4 0 0 4 4 4 2 Zinc-finger of C2H2 type zf-C2H2_3rep PF18868.1 KFX85708.1 - 0.00036 21.2 1.6 0.0011 19.6 1.6 1.9 1 0 0 1 1 1 1 Zinc finger C2H2-type, 3 repeats Glyco_hydro_1 PF00232.18 KFX85708.1 - 0.049 12.1 0.0 0.079 11.4 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 1 zinc_ribbon_15 PF17032.5 KFX85708.1 - 0.1 13.4 3.3 0.26 12.1 3.1 1.9 1 1 0 1 1 1 0 zinc-ribbon family zf-C2H2_11 PF16622.5 KFX85708.1 - 0.13 12.0 0.0 0.13 12.0 0.0 2.8 3 0 0 3 3 3 0 zinc-finger C2H2-type zf-C2H2_jaz PF12171.8 KFX85708.1 - 0.2 12.0 12.8 2.4 8.6 1.3 4.0 4 0 0 4 4 4 0 Zinc-finger double-stranded RNA-binding Zn_ribbon_SprT PF17283.2 KFX85708.1 - 0.8 9.7 5.1 6.9 6.7 4.6 2.5 1 1 0 1 1 1 0 SprT-like zinc ribbon domain zf-C2H2_9 PF16293.5 KFX85708.1 - 1.7 8.5 8.5 0.97 9.3 0.1 3.6 3 0 0 3 3 3 0 C2H2 type zinc-finger (1 copy) GATA PF00320.27 KFX85708.1 - 2.5 7.8 4.7 9 6.0 0.1 2.5 2 0 0 2 2 2 0 GATA zinc finger zf-C2H2_2 PF12756.7 KFX85708.1 - 4.1 7.8 10.1 13 6.2 0.2 3.6 1 1 1 3 3 3 0 C2H2 type zinc-finger (2 copies) DZR PF12773.7 KFX85708.1 - 4.3 7.4 7.2 2 8.5 2.1 2.4 2 0 0 2 2 2 0 Double zinc ribbon Zn-C2H2_12 PF18112.1 KFX85708.1 - 4.3 7.9 8.9 28 5.3 0.1 4.2 4 0 0 4 4 4 0 Autophagy receptor zinc finger-C2H2 domain zf-Di19 PF05605.12 KFX85708.1 - 4.8 7.6 8.7 24 5.3 0.4 3.5 3 0 0 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding zinc-ribbons_6 PF07191.12 KFX85708.1 - 7.8 6.6 10.4 0.89 9.6 2.2 3.0 3 0 0 3 3 3 0 zinc-ribbons Amelogenin PF02948.15 KFX85714.1 - 7.8 7.1 19.4 18 6.0 19.4 1.6 1 1 0 1 1 1 0 Amelogenin KilA-N PF04383.13 KFX85715.1 - 0.0043 16.9 0.0 0.023 14.6 0.0 2.2 1 1 0 1 1 1 1 KilA-N domain Hamartin PF04388.12 KFX85715.1 - 1.4 7.4 9.4 1.7 7.2 9.4 1.1 1 0 0 1 1 1 0 Hamartin protein CytochromB561_N PF09786.9 KFX85715.1 - 3.4 6.5 10.6 4.6 6.1 10.6 1.1 1 0 0 1 1 1 0 Cytochrome B561, N terminal NAD_binding_2 PF03446.15 KFX85716.1 - 4.6e-37 127.6 0.6 6.6e-37 127.1 0.6 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 KFX85716.1 - 1.7e-29 102.5 0.0 2.8e-29 101.8 0.0 1.4 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase F420_oxidored PF03807.17 KFX85716.1 - 1.9e-06 28.3 0.3 7.2e-06 26.5 0.0 1.9 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent OCD_Mu_crystall PF02423.15 KFX85716.1 - 0.00011 21.3 0.2 0.00017 20.7 0.2 1.2 1 0 0 1 1 1 1 Ornithine cyclodeaminase/mu-crystallin family GFO_IDH_MocA PF01408.22 KFX85716.1 - 0.035 14.9 0.0 0.074 13.9 0.0 1.6 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold Mito_carr PF00153.27 KFX85724.1 - 1e-14 54.2 3.9 8e-06 25.7 0.8 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein Copper-bind PF00127.20 KFX85725.1 - 0.0016 18.8 0.2 0.0088 16.5 0.2 2.0 1 1 0 1 1 1 1 Copper binding proteins, plastocyanin/azurin family E1_dh PF00676.20 KFX85725.1 - 0.26 10.2 0.2 0.38 9.6 0.2 1.1 1 0 0 1 1 1 0 Dehydrogenase E1 component Cytochrom_B561 PF03188.16 KFX85726.1 - 1.5e-05 25.1 12.8 6.3e-05 23.1 8.5 2.0 1 1 1 2 2 2 2 Eukaryotic cytochrome b561 DUF2427 PF10348.9 KFX85726.1 - 0.00029 20.6 5.9 0.077 12.8 1.0 3.3 3 1 1 4 4 4 2 Domain of unknown function (DUF2427) PTPLA PF04387.14 KFX85726.1 - 0.026 14.3 0.7 0.07 12.9 0.4 1.9 1 1 1 2 2 2 0 Protein tyrosine phosphatase-like protein, PTPLA DUF373 PF04123.13 KFX85726.1 - 0.12 11.8 3.4 0.15 11.5 3.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF373) DUF485 PF04341.12 KFX85726.1 - 2.5 8.1 5.7 10 6.1 0.0 3.2 3 1 1 4 4 4 0 Protein of unknown function, DUF485 PI3_PI4_kinase PF00454.27 KFX85733.1 - 2.1e-37 129.3 0.0 1.8e-36 126.3 0.0 2.1 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase DUF4135 PF13575.6 KFX85733.1 - 0.026 13.9 0.0 0.043 13.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4135) MFS_1 PF07690.16 KFX85740.1 - 7.3e-21 74.5 70.1 2.2e-18 66.3 36.5 2.6 1 1 2 3 3 3 3 Major Facilitator Superfamily ArAE_2_N PF10337.9 KFX85752.1 - 2.4e-47 162.1 12.1 8.2e-39 133.9 0.5 4.0 2 1 1 3 3 3 3 Putative ER transporter, 6TM, N-terminal FUSC_2 PF13515.6 KFX85752.1 - 1.7e-17 63.7 19.3 1.7e-17 63.7 19.3 2.6 2 0 0 2 2 2 1 Fusaric acid resistance protein-like ArAE_2 PF10334.9 KFX85752.1 - 5.7e-05 23.1 0.0 0.00088 19.2 0.1 2.3 2 0 0 2 2 2 1 Aromatic acid exporter family member 2 DCP2 PF05026.13 KFX85758.1 - 6e-31 106.6 0.6 1.1e-30 105.8 0.6 1.4 1 0 0 1 1 1 1 Dcp2, box A domain NUDIX PF00293.28 KFX85758.1 - 8.2e-18 64.7 0.1 1.5e-17 63.9 0.1 1.4 1 0 0 1 1 1 1 NUDIX domain DUF4112 PF13430.6 KFX85759.1 - 7e-36 122.7 0.3 9.2e-36 122.3 0.3 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4112) UPF0020 PF01170.18 KFX85763.1 - 5.6e-08 32.7 0.0 2e-06 27.6 0.0 2.1 1 1 0 1 1 1 1 Putative RNA methylase family UPF0020 Hexokinase_1 PF00349.21 KFX85770.1 - 1.7e-76 256.6 0.0 2.3e-76 256.1 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Hexokinase_2 PF03727.16 KFX85770.1 - 3.4e-51 174.0 0.0 4.7e-51 173.5 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Hydrolase_4 PF12146.8 KFX85777.1 - 3.3e-48 164.1 0.0 5.6e-48 163.3 0.0 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KFX85777.1 - 6.7e-12 46.5 3.5 6.7e-12 46.5 3.5 2.3 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KFX85777.1 - 1.2e-08 34.9 0.0 4e-08 33.2 0.0 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold GCD14 PF08704.10 KFX85777.1 - 0.00039 20.2 0.0 0.01 15.6 0.0 2.3 2 0 0 2 2 2 1 tRNA methyltransferase complex GCD14 subunit Peptidase_S9 PF00326.21 KFX85777.1 - 0.0036 16.8 0.2 0.024 14.1 0.0 2.3 2 1 1 3 3 3 1 Prolyl oligopeptidase family Methyltransf_31 PF13847.6 KFX85777.1 - 0.0084 15.9 0.0 0.26 11.1 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_24 PF13578.6 KFX85777.1 - 0.025 15.6 1.1 0.47 11.5 0.0 3.2 4 0 0 4 4 4 0 Methyltransferase domain GCD14_N PF14801.6 KFX85777.1 - 0.037 13.9 0.0 0.085 12.7 0.0 1.5 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit N-term Lipase_3 PF01764.25 KFX85777.1 - 0.073 12.9 0.0 0.18 11.6 0.0 1.6 1 0 0 1 1 1 0 Lipase (class 3) PGAP1 PF07819.13 KFX85777.1 - 0.12 12.1 0.0 0.33 10.6 0.0 1.7 2 0 0 2 2 2 0 PGAP1-like protein ArsA_ATPase PF02374.15 KFX85784.1 - 1.9e-113 378.7 0.0 2.2e-113 378.5 0.0 1.0 1 0 0 1 1 1 1 Anion-transporting ATPase AAA_31 PF13614.6 KFX85784.1 - 3.5e-13 49.9 0.1 6.1e-12 45.8 0.0 2.4 2 2 0 2 2 2 1 AAA domain CbiA PF01656.23 KFX85784.1 - 2.3e-12 47.1 0.0 4.1e-12 46.3 0.0 1.7 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain ParA PF10609.9 KFX85784.1 - 2.3e-06 27.3 0.3 0.00029 20.4 0.0 2.4 2 0 0 2 2 2 1 NUBPL iron-transfer P-loop NTPase Fer4_NifH PF00142.18 KFX85784.1 - 6e-06 25.9 0.0 1e-05 25.1 0.0 1.4 1 0 0 1 1 1 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family SRP54 PF00448.22 KFX85784.1 - 6.9e-05 22.6 0.2 0.0027 17.4 0.0 2.5 3 0 0 3 3 3 1 SRP54-type protein, GTPase domain CBP_BcsQ PF06564.12 KFX85784.1 - 0.00013 21.6 0.0 0.00029 20.4 0.0 1.6 1 0 0 1 1 1 1 Cellulose biosynthesis protein BcsQ AAA_16 PF13191.6 KFX85784.1 - 0.0067 16.8 0.0 0.01 16.3 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain AAA_25 PF13481.6 KFX85784.1 - 0.031 13.9 0.1 0.075 12.6 0.1 1.8 1 1 0 1 1 1 0 AAA domain NB-ARC PF00931.22 KFX85784.1 - 0.14 11.3 0.0 0.25 10.5 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain RecG_N PF17190.4 KFX85784.1 - 0.16 12.7 1.7 0.34 11.7 0.7 2.0 2 0 0 2 2 2 0 RecG N-terminal helical domain ATE_C PF04377.15 KFX85788.1 - 7.6e-45 152.8 0.1 1.7e-44 151.7 0.1 1.6 1 0 0 1 1 1 1 Arginine-tRNA-protein transferase, C terminus ATE_N PF04376.13 KFX85788.1 - 1.8e-24 85.9 2.2 3.8e-24 84.9 2.2 1.6 1 0 0 1 1 1 1 Arginine-tRNA-protein transferase, N terminus Acetyltransf_6 PF13480.7 KFX85788.1 - 0.0041 17.3 0.5 0.0096 16.1 0.5 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain UPF0113_N PF17833.1 KFX85793.1 - 1.7e-23 83.0 0.0 2.2e-23 82.6 0.0 1.2 1 0 0 1 1 1 1 UPF0113 Pre-PUA domain UPF0113 PF03657.13 KFX85793.1 - 2.2e-23 82.3 0.0 3.2e-23 81.8 0.0 1.3 1 0 0 1 1 1 1 UPF0113 PUA domain PUA PF01472.20 KFX85793.1 - 0.23 11.5 0.0 0.38 10.7 0.0 1.4 1 0 0 1 1 1 0 PUA domain NOC3p PF07540.11 KFX85794.1 - 8.8e-30 103.0 0.2 2.8e-29 101.4 0.2 1.9 1 0 0 1 1 1 1 Nucleolar complex-associated protein CBF PF03914.17 KFX85794.1 - 5.3e-24 85.2 0.1 1.3e-23 83.8 0.1 1.7 1 0 0 1 1 1 1 CBF/Mak21 family Patatin PF01734.22 KFX85797.1 - 2.6e-13 50.6 0.1 6e-13 49.4 0.1 1.6 1 0 0 1 1 1 1 Patatin-like phospholipase Fungal_trans PF04082.18 KFX85807.1 - 0.0083 15.2 0.0 0.014 14.5 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain FAD_binding_3 PF01494.19 KFX85808.1 - 3.4e-29 102.2 0.1 3.2e-28 99.0 0.1 2.0 1 1 0 1 1 1 1 FAD binding domain Amino_oxidase PF01593.24 KFX85808.1 - 9.4e-08 31.8 0.4 0.0024 17.3 0.0 2.7 1 1 1 2 2 2 2 Flavin containing amine oxidoreductase Pyr_redox_3 PF13738.6 KFX85808.1 - 9.5e-07 28.4 0.1 2.7e-05 23.6 0.2 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KFX85808.1 - 2.3e-05 24.5 0.3 8.5e-05 22.7 0.2 2.1 1 1 1 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KFX85808.1 - 0.00017 20.9 0.5 0.029 13.6 0.1 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KFX85808.1 - 0.00059 18.7 0.4 0.036 12.8 0.2 2.1 2 0 0 2 2 2 1 HI0933-like protein Lycopene_cycl PF05834.12 KFX85808.1 - 0.00063 18.9 1.1 0.28 10.2 0.0 2.1 2 0 0 2 2 2 2 Lycopene cyclase protein Thi4 PF01946.17 KFX85808.1 - 0.00073 18.8 0.3 0.0033 16.7 0.2 1.9 2 0 0 2 2 2 1 Thi4 family DAO PF01266.24 KFX85808.1 - 0.0017 18.0 2.5 0.005 16.5 1.6 2.0 2 1 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 KFX85808.1 - 0.0081 16.7 1.5 0.036 14.6 0.8 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KFX85808.1 - 0.019 14.0 1.0 0.03 13.4 1.0 1.3 1 0 0 1 1 1 0 FAD binding domain Trp_halogenase PF04820.14 KFX85808.1 - 0.022 13.6 0.0 0.034 13.0 0.0 1.3 1 0 0 1 1 1 0 Tryptophan halogenase TrkA_N PF02254.18 KFX85808.1 - 0.048 13.9 0.5 0.12 12.7 0.2 1.7 2 0 0 2 2 2 0 TrkA-N domain ThiF PF00899.21 KFX85808.1 - 0.07 12.5 0.1 0.13 11.5 0.1 1.3 1 0 0 1 1 1 0 ThiF family ApbA PF02558.16 KFX85808.1 - 0.12 12.0 0.3 0.24 11.0 0.3 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA FAD_oxidored PF12831.7 KFX85808.1 - 0.16 11.3 0.3 0.46 9.8 0.3 1.8 1 1 0 1 1 1 0 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 KFX85808.1 - 0.21 11.5 1.3 22 5.0 0.1 3.0 3 0 0 3 3 3 0 FAD-NAD(P)-binding His_Phos_2 PF00328.22 KFX85812.1 - 3.6e-42 145.1 0.0 4.8e-42 144.7 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) PPIP5K2_N PF18086.1 KFX85812.1 - 5.9e-36 122.5 0.0 1.3e-35 121.4 0.0 1.5 1 0 0 1 1 1 1 Diphosphoinositol pentakisphosphate kinase 2 N-terminal domain RimK PF08443.11 KFX85812.1 - 1.6e-05 24.6 0.0 3.5e-05 23.5 0.0 1.5 1 0 0 1 1 1 1 RimK-like ATP-grasp domain GH131_N PF18271.1 KFX85814.1 - 6.5e-68 229.2 0.0 8.4e-68 228.8 0.0 1.1 1 0 0 1 1 1 1 Glycoside hydrolase 131 catalytic N-terminal domain DnaA_N PF11638.8 KFX85814.1 - 0.064 13.0 0.0 0.16 11.7 0.0 1.7 1 0 0 1 1 1 0 DnaA N-terminal domain Glyco_hydro_18 PF00704.28 KFX85815.1 - 0.00011 22.0 0.0 0.00015 21.6 0.0 1.3 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 Mcp5_PH PF12814.7 KFX85819.1 - 2.1e-48 163.4 0.0 4.5e-48 162.4 0.0 1.6 1 0 0 1 1 1 1 Meiotic cell cortex C-terminal pleckstrin homology Fez1 PF06818.15 KFX85819.1 - 0.0024 18.4 8.4 0.0058 17.1 8.4 1.6 1 0 0 1 1 1 1 Fez1 DUF724 PF05266.14 KFX85819.1 - 0.04 13.8 2.2 0.087 12.7 2.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF724) ATG16 PF08614.11 KFX85819.1 - 0.34 11.1 16.6 2 8.6 7.3 2.8 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) SlyX PF04102.12 KFX85819.1 - 0.38 11.4 2.5 0.71 10.5 0.2 2.7 3 1 1 4 4 4 0 SlyX CCDC-167 PF15188.6 KFX85819.1 - 0.48 10.8 6.4 2.4 8.5 2.5 2.7 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 167 TPR_MLP1_2 PF07926.12 KFX85819.1 - 0.56 10.3 13.5 5.3 7.1 10.0 2.4 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein GAS PF13851.6 KFX85819.1 - 0.99 8.7 6.8 1.7 7.9 6.8 1.3 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding Macoilin PF09726.9 KFX85819.1 - 1 7.8 5.6 2.7 6.4 5.6 1.7 1 0 0 1 1 1 0 Macoilin family HIP1_clath_bdg PF16515.5 KFX85819.1 - 1.3 9.7 11.9 0.05 14.2 2.9 2.6 1 1 1 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 WD40 PF00400.32 KFX85820.1 - 2.7e-06 28.0 0.1 0.0047 17.7 0.0 3.1 4 0 0 4 4 4 2 WD domain, G-beta repeat Aminotran_5 PF00266.19 KFX85821.1 - 7e-28 97.6 0.0 9e-28 97.3 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.21 KFX85821.1 - 0.001 18.3 0.0 0.0018 17.5 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II KR PF08659.10 KFX85821.1 - 0.028 14.3 0.0 0.056 13.3 0.0 1.5 1 0 0 1 1 1 0 KR domain B12-binding PF02310.19 KFX85821.1 - 0.03 14.3 0.0 0.11 12.5 0.0 2.0 1 1 0 1 1 1 0 B12 binding domain Fungal_trans PF04082.18 KFX85825.1 - 2.8e-27 95.4 1.1 4.2e-27 94.9 1.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KFX85825.1 - 2.2e-06 27.7 6.4 4.6e-06 26.7 6.4 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-C2H2_2 PF12756.7 KFX85827.1 - 2.3e-32 111.3 7.7 1.5e-26 92.6 0.5 3.6 3 0 0 3 3 3 3 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.8 KFX85827.1 - 1.6e-07 31.4 7.5 0.016 15.5 1.3 4.1 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KFX85827.1 - 0.0035 17.7 1.6 0.0035 17.7 1.6 3.2 3 0 0 3 3 3 1 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.6 KFX85827.1 - 0.015 16.1 13.5 4.9 8.3 0.1 5.1 5 0 0 5 5 5 0 C2H2-type zinc finger zf-C2H2 PF00096.26 KFX85827.1 - 0.081 13.4 0.4 0.081 13.4 0.4 4.5 4 0 0 4 4 4 0 Zinc finger, C2H2 type AKAP95 PF04988.12 KFX85827.1 - 0.25 11.6 4.3 1.1 9.4 0.4 3.1 2 1 1 3 3 3 0 A-kinase anchoring protein 95 (AKAP95) DUF4820 PF16091.5 KFX85827.1 - 2.6 7.3 8.2 34 3.7 5.7 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4820) X8 PF07983.13 KFX85832.1 - 1.4e-20 73.7 2.0 2.1e-20 73.2 2.0 1.3 1 0 0 1 1 1 1 X8 domain CTP_transf_like PF01467.26 KFX85845.1 - 0.0054 16.9 0.0 0.079 13.2 0.0 2.3 2 0 0 2 2 2 1 Cytidylyltransferase-like Pkinase PF00069.25 KFX85849.1 - 2.1e-27 96.2 0.0 2.9e-27 95.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFX85849.1 - 7.6e-16 58.2 0.0 1.4e-15 57.3 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase F-box-like PF12937.7 KFX85849.1 - 0.014 15.3 2.0 0.056 13.4 0.5 2.3 2 0 0 2 2 2 0 F-box-like CTP_transf_like PF01467.26 KFX85860.1 - 0.045 14.0 0.0 0.17 12.1 0.0 1.9 2 0 0 2 2 2 0 Cytidylyltransferase-like MFS_1 PF07690.16 KFX85861.1 - 8.1e-24 84.2 20.7 9.4e-24 84.0 20.7 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 KFX85861.1 - 0.011 14.2 2.4 0.013 14.0 2.4 1.1 1 0 0 1 1 1 0 Fungal trichothecene efflux pump (TRI12) DUF3464 PF11947.8 KFX85861.1 - 0.92 9.3 2.9 14 5.5 0.0 2.9 3 0 0 3 3 3 0 Photosynthesis affected mutant 68 Adeno_E3_CR2 PF02439.15 KFX85861.1 - 2.4 8.0 4.4 6.7 6.6 4.4 1.7 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 zf-His_Me_endon PF05551.11 KFX85863.1 - 3.8e-12 46.5 2.6 3.8e-12 46.5 2.6 2.4 2 1 0 2 2 2 1 Zinc-binding loop region of homing endonuclease Sugar_tr PF00083.24 KFX85869.1 - 1.8e-108 363.3 23.7 2.2e-108 363.0 23.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KFX85869.1 - 1.7e-23 83.2 37.9 3.3e-22 78.9 27.6 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 KFX85869.1 - 8e-05 21.2 0.8 8e-05 21.2 0.8 2.3 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Popeye PF04831.13 KFX85869.1 - 7.1 6.8 6.6 23 5.2 6.2 2.0 1 1 0 1 1 1 0 Popeye protein conserved region AAA PF00004.29 KFX85881.1 - 1.6e-37 128.8 0.0 4e-37 127.6 0.0 1.7 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KFX85881.1 - 4.2e-08 32.9 0.1 9e-08 31.8 0.1 1.6 1 0 0 1 1 1 1 AAA+ lid domain RuvB_N PF05496.12 KFX85881.1 - 1.9e-05 24.5 0.0 3.6e-05 23.6 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 KFX85881.1 - 2.8e-05 24.6 1.2 0.00043 20.7 0.0 2.7 2 1 1 3 3 3 1 AAA ATPase domain AAA_22 PF13401.6 KFX85881.1 - 4.2e-05 23.8 0.2 0.0092 16.3 0.0 3.1 1 1 2 3 3 3 1 AAA domain AAA_5 PF07728.14 KFX85881.1 - 4.3e-05 23.5 0.3 0.00057 19.9 0.3 2.7 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_14 PF13173.6 KFX85881.1 - 6.2e-05 23.0 0.0 0.00013 22.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_2 PF07724.14 KFX85881.1 - 7.3e-05 22.9 0.0 0.00016 21.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_33 PF13671.6 KFX85881.1 - 0.00053 20.2 0.0 0.0013 19.0 0.0 1.8 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 KFX85881.1 - 0.00061 19.6 0.0 0.0012 18.7 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_18 PF13238.6 KFX85881.1 - 0.00083 19.9 0.1 0.0036 17.8 0.0 2.1 2 0 0 2 2 2 1 AAA domain Mg_chelatase PF01078.21 KFX85881.1 - 0.00096 18.6 0.1 0.0021 17.5 0.1 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_25 PF13481.6 KFX85881.1 - 0.0012 18.5 0.2 0.025 14.2 0.1 2.8 3 0 0 3 3 3 1 AAA domain RNA_helicase PF00910.22 KFX85881.1 - 0.002 18.5 0.0 0.0052 17.2 0.0 1.8 1 0 0 1 1 1 1 RNA helicase TniB PF05621.11 KFX85881.1 - 0.0022 17.4 0.0 3.2 7.1 0.0 2.8 2 1 0 3 3 3 2 Bacterial TniB protein NACHT PF05729.12 KFX85881.1 - 0.0037 17.2 0.0 0.015 15.2 0.0 2.0 2 0 0 2 2 2 1 NACHT domain AAA_28 PF13521.6 KFX85881.1 - 0.0074 16.5 0.0 0.018 15.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain Sigma54_activ_2 PF14532.6 KFX85881.1 - 0.0084 16.2 0.0 0.016 15.3 0.0 1.4 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA_24 PF13479.6 KFX85881.1 - 0.0087 15.8 0.0 0.015 15.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain Rad17 PF03215.15 KFX85881.1 - 0.017 15.0 0.1 0.043 13.7 0.1 1.5 1 1 0 1 1 1 0 Rad17 P-loop domain Sigma54_activat PF00158.26 KFX85881.1 - 0.018 14.7 0.0 0.042 13.6 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain ABC_tran PF00005.27 KFX85881.1 - 0.023 15.2 0.0 0.054 14.0 0.0 1.8 1 1 0 1 1 1 0 ABC transporter CPT PF07931.12 KFX85881.1 - 0.023 14.6 1.5 0.16 11.8 0.0 2.7 3 0 0 3 3 3 0 Chloramphenicol phosphotransferase-like protein Parvo_NS1 PF01057.17 KFX85881.1 - 0.026 13.6 0.0 0.041 13.0 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 TIP49 PF06068.13 KFX85881.1 - 0.033 13.4 0.1 0.39 9.9 0.0 2.1 2 0 0 2 2 2 0 TIP49 P-loop domain Guanylate_kin PF00625.21 KFX85881.1 - 0.058 13.1 0.0 1.7 8.3 0.0 2.8 2 1 1 3 3 3 0 Guanylate kinase AAA_7 PF12775.7 KFX85881.1 - 0.064 12.8 0.0 0.13 11.7 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region DUF815 PF05673.13 KFX85881.1 - 0.077 12.1 0.0 0.15 11.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) ATPase_2 PF01637.18 KFX85881.1 - 0.079 12.9 0.0 0.22 11.4 0.0 1.7 1 1 1 2 2 2 0 ATPase domain predominantly from Archaea NB-ARC PF00931.22 KFX85881.1 - 0.079 12.1 0.0 0.59 9.3 0.0 2.0 2 0 0 2 2 2 0 NB-ARC domain TsaE PF02367.17 KFX85881.1 - 0.097 12.7 0.0 0.17 11.9 0.0 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Zeta_toxin PF06414.12 KFX85881.1 - 0.11 11.8 0.0 0.24 10.7 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin ATPase PF06745.13 KFX85881.1 - 0.12 11.7 0.0 0.76 9.1 0.0 2.0 1 1 1 2 2 2 0 KaiC Viral_helicase1 PF01443.18 KFX85881.1 - 0.13 11.9 0.0 0.24 11.1 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase zf-C2H2_4 PF13894.6 KFX85884.1 - 0.063 14.1 0.3 0.22 12.4 0.3 2.0 1 0 0 1 1 1 0 C2H2-type zinc finger DUF641 PF04859.12 KFX85884.1 - 0.076 13.4 0.4 2 8.7 0.2 2.4 2 0 0 2 2 2 0 Plant protein of unknown function (DUF641) Csm1_N PF18504.1 KFX85884.1 - 0.084 13.2 0.5 2.6 8.4 0.6 2.7 2 0 0 2 2 2 0 Csm1 N-terminal domain zf-Di19 PF05605.12 KFX85884.1 - 0.14 12.5 0.1 0.27 11.6 0.1 1.4 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding GOLGA2L5 PF15070.6 KFX85884.1 - 0.16 10.6 2.2 0.29 9.7 2.2 1.3 1 0 0 1 1 1 0 Putative golgin subfamily A member 2-like protein 5 DivIC PF04977.15 KFX85884.1 - 1 9.2 2.6 2.1 8.2 2.6 1.4 1 0 0 1 1 1 0 Septum formation initiator TolA_bind_tri PF16331.5 KFX85884.1 - 4.3 7.5 7.9 0.87 9.7 1.9 2.8 3 0 0 3 3 3 0 TolA binding protein trimerisation His_Phos_1 PF00300.22 KFX85885.1 - 4.5e-12 46.1 0.6 1.3e-10 41.3 0.6 2.2 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) His_Phos_2 PF00328.22 KFX85889.1 - 1.9e-48 165.8 0.0 2.2e-48 165.6 0.0 1.0 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) DUF4628 PF15429.6 KFX85892.1 - 0.91 9.1 4.8 1.4 8.6 4.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4628) Coiled-coil_56 PF09813.9 KFX85899.1 - 0.087 12.9 2.1 0.15 12.2 0.1 2.0 1 1 1 2 2 2 0 Coiled-coil domain-containing protein 56 RRP7 PF12923.7 KFX85910.1 - 0.36 11.0 4.4 1.2 9.3 4.4 1.8 1 1 0 1 1 1 0 Ribosomal RNA-processing protein 7 (RRP7) C-terminal domain JCAD PF15351.6 KFX85910.1 - 1.3 6.8 7.4 1.3 6.7 7.4 1.0 1 0 0 1 1 1 0 Junctional protein associated with coronary artery disease BSD PF03909.17 KFX85911.1 - 8.6e-17 60.9 0.0 1.7e-16 59.9 0.0 1.5 1 0 0 1 1 1 1 BSD domain Suf PF05843.14 KFX85911.1 - 0.019 15.0 0.0 0.036 14.0 0.0 1.4 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Trs65 PF12735.7 KFX85914.1 - 5.2e-43 147.7 0.0 5.7e-43 147.5 0.0 1.0 1 0 0 1 1 1 1 TRAPP trafficking subunit Trs65 Fungal_trans PF04082.18 KFX85915.1 - 1.3e-18 67.0 1.0 2.2e-18 66.3 0.0 1.9 2 0 0 2 2 2 1 Fungal specific transcription factor domain TFIIA PF03153.13 KFX85915.1 - 0.0047 17.0 31.5 0.0065 16.5 31.5 1.2 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Tmemb_170 PF10190.9 KFX85919.1 - 1.6e-13 50.9 4.1 2e-13 50.6 4.1 1.1 1 0 0 1 1 1 1 Putative transmembrane protein 170 LRR_6 PF13516.6 KFX85922.1 - 2.4e-07 30.2 7.7 0.07 13.2 0.1 6.2 7 0 0 7 7 7 2 Leucine Rich repeat LRR_4 PF12799.7 KFX85922.1 - 3.6e-06 27.2 10.9 1.8 9.1 1.8 6.1 6 1 1 7 7 7 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 KFX85922.1 - 0.021 15.3 2.8 11 7.1 0.0 4.5 5 0 0 5 5 5 0 Leucine Rich Repeat NOA36 PF06524.12 KFX85922.1 - 0.03 13.7 4.4 0.043 13.1 4.4 1.2 1 0 0 1 1 1 0 NOA36 protein LRR_8 PF13855.6 KFX85922.1 - 1.1 9.1 11.9 1.6 8.6 0.0 4.6 4 1 0 4 4 4 0 Leucine rich repeat RRN3 PF05327.11 KFX85922.1 - 2 6.9 12.5 2.9 6.3 12.5 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 COX17 PF05051.13 KFX85923.1 - 6.4e-21 74.4 6.0 7.7e-21 74.2 6.0 1.1 1 0 0 1 1 1 1 Cytochrome C oxidase copper chaperone (COX17) zf-C2H2 PF00096.26 KFX85925.1 - 4.4e-28 96.1 48.2 0.0003 21.1 0.3 10.8 10 0 0 10 10 10 9 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFX85925.1 - 8.5e-21 72.9 51.3 0.075 13.9 0.3 11.6 10 2 1 11 11 11 8 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFX85925.1 - 4e-08 33.3 30.4 0.2 12.0 0.6 9.0 11 0 0 11 11 11 4 Zinc-finger double-stranded RNA-binding FOXP-CC PF16159.5 KFX85925.1 - 2.2e-06 28.2 29.3 0.62 10.7 0.1 8.6 4 2 5 9 9 9 3 FOXP coiled-coil domain zf-H2C2_2 PF13465.6 KFX85925.1 - 0.00022 21.5 0.1 0.00022 21.5 0.1 10.8 12 1 0 12 12 12 3 Zinc-finger double domain zf-met PF12874.7 KFX85925.1 - 0.00058 20.2 20.7 1.6 9.2 0.1 8.3 8 0 0 8 8 8 1 Zinc-finger of C2H2 type zf-C2H2_8 PF15909.5 KFX85925.1 - 0.0019 18.5 21.0 1.4 9.3 4.6 4.9 3 2 3 6 6 6 4 C2H2-type zinc ribbon zf_ZIC PF18366.1 KFX85925.1 - 0.0037 17.3 5.8 15 5.8 0.0 5.6 6 0 0 6 6 6 0 Zic proteins zinc finger domain DUF4187 PF13821.6 KFX85925.1 - 0.0055 16.4 1.6 0.02 14.7 0.2 2.5 2 0 0 2 2 2 1 Domain of unknown function (DUF4187) ROS_MUCR PF05443.11 KFX85925.1 - 0.21 11.7 1.6 4.3 7.4 0.0 3.1 3 0 0 3 3 3 0 ROS/MUCR transcriptional regulator protein zf_Hakai PF18408.1 KFX85925.1 - 0.25 11.1 26.9 0.15 11.8 0.5 6.0 6 0 0 6 6 6 0 C2H2 Hakai zinc finger domain zf-C2H2_aberr PF17017.5 KFX85925.1 - 8.7 6.5 24.6 0.16 12.1 1.1 4.9 4 2 4 8 8 8 0 Aberrant zinc-finger RNA_pol_Rpb6 PF01192.22 KFX85926.1 - 5e-17 61.6 0.2 7.6e-17 61.0 0.2 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb6 Ank_2 PF12796.7 KFX85932.1 - 2.6e-34 117.7 1.8 2.7e-12 47.1 0.0 3.2 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KFX85932.1 - 1e-25 86.9 0.5 0.027 15.0 0.0 6.9 7 0 0 7 7 7 6 Ankyrin repeat Ank_4 PF13637.6 KFX85932.1 - 8.4e-25 86.8 0.0 1.9e-07 31.5 0.0 4.5 4 1 0 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.30 KFX85932.1 - 2.1e-20 72.2 7.8 0.05 14.1 0.0 7.1 6 1 1 7 7 7 6 Ankyrin repeat Ank_5 PF13857.6 KFX85932.1 - 3.4e-18 65.5 6.3 0.0017 18.6 0.0 6.7 1 1 6 7 7 7 5 Ankyrin repeats (many copies) CDC45 PF02724.14 KFX85933.1 - 0.56 8.4 2.6 0.83 7.9 2.6 1.2 1 0 0 1 1 1 0 CDC45-like protein Ribophorin_I PF04597.14 KFX85937.1 - 1.7e-74 251.6 2.4 2e-74 251.4 2.4 1.0 1 0 0 1 1 1 1 Ribophorin I Lipoprotein_17 PF04200.12 KFX85937.1 - 0.57 10.6 3.4 1.6 9.2 3.4 1.8 1 1 1 2 2 2 0 Lipoprotein associated domain Nucleos_tra2_C PF07662.13 KFX85941.1 - 3.9e-68 229.4 1.1 4.4e-68 229.2 1.1 1.0 1 0 0 1 1 1 1 Na+ dependent nucleoside transporter C-terminus ATP1G1_PLM_MAT8 PF02038.16 KFX85941.1 - 0.082 12.4 1.4 0.2 11.1 1.4 1.6 1 0 0 1 1 1 0 ATP1G1/PLM/MAT8 family DUF2569 PF10754.9 KFX85941.1 - 2 8.8 6.4 7.6 7.0 3.3 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2569) Ion_trans_2 PF07885.16 KFX85943.1 - 2.3e-31 107.6 26.4 1.9e-17 63.0 5.4 3.3 3 0 0 3 3 3 2 Ion channel IRK PF01007.20 KFX85943.1 - 0.006 16.4 6.0 0.74 9.6 2.1 3.5 2 1 0 2 2 2 1 Inward rectifier potassium channel transmembrane domain HemY_N PF07219.13 KFX85943.1 - 0.17 12.1 5.2 7.3 6.8 0.3 3.7 3 0 0 3 3 3 0 HemY protein N-terminus Tnp_P_element_C PF12596.8 KFX85947.1 - 0.13 12.8 0.0 0.36 11.4 0.0 1.7 2 0 0 2 2 2 0 87kDa Transposase Gryzun PF07919.12 KFX85953.1 - 5.6e-161 537.3 0.0 6.2e-161 537.1 0.0 1.0 1 0 0 1 1 1 1 Gryzun, putative trafficking through Golgi Gryzun-like PF12742.7 KFX85953.1 - 0.0015 18.5 0.3 0.0055 16.7 0.0 2.0 2 0 0 2 2 2 1 Gryzun, putative Golgi trafficking GYD PF08734.11 KFX85953.1 - 0.23 11.4 0.0 0.45 10.5 0.0 1.4 1 0 0 1 1 1 0 GYD domain Abhydrolase_6 PF12697.7 KFX85954.1 - 6.6e-09 36.7 1.1 9.2e-09 36.2 1.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KFX85954.1 - 0.15 11.6 0.0 0.69 9.5 0.1 1.9 2 0 0 2 2 2 0 alpha/beta hydrolase fold Thioredoxin_2 PF13098.6 KFX85954.1 - 0.18 12.2 0.0 0.31 11.5 0.0 1.4 1 0 0 1 1 1 0 Thioredoxin-like domain DUF4187 PF13821.6 KFX85956.1 - 0.15 11.8 0.1 0.32 10.8 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4187) DUF1741 PF08427.10 KFX85958.1 - 3.4e-09 36.7 0.4 7.8e-09 35.5 0.4 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1741) IFRD PF05004.13 KFX85958.1 - 0.028 13.5 0.1 0.077 12.1 0.1 1.6 1 1 1 2 2 2 0 Interferon-related developmental regulator (IFRD) ICE2 PF08426.10 KFX85963.1 - 1e-76 258.7 7.6 1.1e-76 258.6 7.6 1.0 1 0 0 1 1 1 1 ICE2 FtsK_4TM PF13491.6 KFX85963.1 - 3.2 7.4 10.5 2.1 8.0 0.1 2.6 3 0 0 3 3 3 0 4TM region of DNA translocase FtsK/SpoIIIE UPF0160 PF03690.13 KFX85964.1 - 1.1e-93 314.4 0.0 1.4e-93 314.1 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0160) Etmic-2 PF06670.11 KFX85964.1 - 0.094 11.6 0.0 0.12 11.3 0.0 1.1 1 0 0 1 1 1 0 Microneme protein Etmic-2 Reticulon PF02453.17 KFX85966.1 - 8e-23 81.1 1.0 1.1e-22 80.7 1.0 1.2 1 0 0 1 1 1 1 Reticulon FlgN PF05130.12 KFX85966.1 - 0.13 12.8 0.1 0.19 12.2 0.1 1.2 1 0 0 1 1 1 0 FlgN protein Aminotran_1_2 PF00155.21 KFX85967.1 - 1e-43 149.9 0.0 1.1e-43 149.8 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Alliinase_C PF04864.13 KFX85967.1 - 0.095 11.6 0.0 0.13 11.1 0.0 1.1 1 0 0 1 1 1 0 Allinase Cation_efflux PF01545.21 KFX85971.1 - 5e-47 160.2 14.2 2.1e-46 158.2 14.2 1.8 1 1 0 1 1 1 1 Cation efflux family ZT_dimer PF16916.5 KFX85971.1 - 0.0088 16.1 0.1 0.022 14.9 0.1 1.7 1 0 0 1 1 1 1 Dimerisation domain of Zinc Transporter ADH_N PF08240.12 KFX85976.1 - 1.6e-19 69.8 0.5 1.8e-18 66.4 0.4 2.4 2 1 1 3 3 3 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KFX85976.1 - 8.2e-07 29.1 0.0 1.4e-06 28.3 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 KFX85976.1 - 0.032 13.5 0.8 0.074 12.3 0.1 1.8 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_2 PF00890.24 KFX85976.1 - 0.036 13.2 0.2 0.052 12.6 0.2 1.2 1 0 0 1 1 1 0 FAD binding domain ADH_N_assoc PF13823.6 KFX85976.1 - 0.068 13.1 0.2 0.068 13.1 0.2 1.9 2 1 0 2 2 2 0 Alcohol dehydrogenase GroES-associated FAD_oxidored PF12831.7 KFX85976.1 - 0.072 12.4 0.2 0.11 11.8 0.2 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase 3HCDH_N PF02737.18 KFX85976.1 - 0.22 11.4 0.6 0.55 10.1 0.0 1.8 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain PCRF PF03462.18 KFX85977.1 - 2.5e-50 171.1 0.0 3.1e-50 170.7 0.0 1.1 1 0 0 1 1 1 1 PCRF domain RF-1 PF00472.20 KFX85977.1 - 5.6e-08 32.7 0.0 1.4e-07 31.5 0.0 1.6 1 0 0 1 1 1 1 RF-1 domain OTU PF02338.19 KFX85980.1 - 5e-07 30.3 0.0 8.7e-07 29.5 0.0 1.4 1 0 0 1 1 1 1 OTU-like cysteine protease Peptidase_C65 PF10275.9 KFX85980.1 - 0.07 12.6 0.0 1.2 8.5 0.0 2.2 2 0 0 2 2 2 0 Peptidase C65 Otubain Vps39_2 PF10367.9 KFX85991.1 - 3.7e-05 24.1 0.0 5e-05 23.7 0.0 1.2 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 2 PseudoU_synth_2 PF00849.22 KFX85993.1 - 2.6e-25 89.4 0.0 4.5e-25 88.6 0.0 1.4 1 0 0 1 1 1 1 RNA pseudouridylate synthase Ub-Mut7C PF14451.6 KFX85993.1 - 0.0047 16.7 0.1 0.011 15.5 0.1 1.6 1 0 0 1 1 1 1 Mut7-C ubiquitin Auto_anti-p27 PF06677.12 KFX85993.1 - 0.033 14.4 0.1 0.08 13.1 0.1 1.6 1 0 0 1 1 1 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) S4 PF01479.25 KFX85993.1 - 0.11 12.2 1.1 0.25 11.1 1.1 1.5 1 0 0 1 1 1 0 S4 domain HCO3_cotransp PF00955.21 KFX85995.1 - 1.3e-83 281.6 15.5 4.5e-44 151.1 8.2 2.1 1 1 1 2 2 2 2 HCO3- transporter family p450 PF00067.22 KFX85998.1 - 4.7e-10 38.8 0.0 5.5e-10 38.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Abhydrolase_6 PF12697.7 KFX85999.1 - 3.5e-13 50.7 0.0 5.8e-13 50.0 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KFX85999.1 - 8.7e-09 35.4 0.0 1.8e-08 34.4 0.0 1.5 2 0 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KFX85999.1 - 0.00047 19.5 0.0 0.00064 19.1 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Ser_hydrolase PF06821.13 KFX85999.1 - 0.001 18.9 0.0 0.0018 18.2 0.0 1.3 1 0 0 1 1 1 1 Serine hydrolase DUF1057 PF06342.12 KFX85999.1 - 0.027 13.5 0.0 2.2 7.2 0.0 2.1 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF1057) bPH_6 PF10756.9 KFX85999.1 - 0.054 13.6 0.6 0.15 12.2 0.1 1.9 2 0 0 2 2 2 0 Bacterial PH domain PRP4 PF08799.11 KFX86000.1 - 9.3e-13 47.5 0.7 9.3e-13 47.5 0.7 1.9 2 0 0 2 2 2 1 pre-mRNA processing factor 4 (PRP4) like MutS_I PF01624.20 KFX86002.1 - 2.9e-19 69.4 0.0 5.1e-19 68.6 0.0 1.3 1 0 0 1 1 1 1 MutS domain I MutS_II PF05188.17 KFX86002.1 - 1.4e-09 38.3 0.0 2.2e-09 37.7 0.0 1.4 1 0 0 1 1 1 1 MutS domain II RPN1_RPN2_N PF17781.1 KFX86002.1 - 0.1 12.0 0.0 0.14 11.5 0.0 1.2 1 0 0 1 1 1 0 RPN1/RPN2 N-terminal domain FMN_red PF03358.15 KFX86003.1 - 9.5e-11 41.7 0.0 1.2e-10 41.3 0.0 1.2 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.17 KFX86003.1 - 7.5e-05 22.5 0.0 9.5e-05 22.2 0.0 1.1 1 0 0 1 1 1 1 Flavodoxin-like fold Flavodoxin_1 PF00258.25 KFX86003.1 - 0.00098 19.4 0.0 0.0098 16.1 0.0 2.2 1 1 0 1 1 1 1 Flavodoxin Zn_clus PF00172.18 KFX86004.1 - 3.2e-08 33.6 10.9 5.3e-08 32.8 10.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KFX86004.1 - 0.0031 16.6 0.2 0.0049 15.9 0.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF4637 PF15470.6 KFX86006.1 - 9.5 5.9 8.6 11 5.7 8.0 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4637) DUF3176 PF11374.8 KFX86008.1 - 2.5e-33 114.5 1.1 5.1e-33 113.5 1.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3176) Pkinase PF00069.25 KFX86010.1 - 1.6e-31 109.6 0.4 2.4e-22 79.6 0.1 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KFX86010.1 - 1.7e-11 43.9 0.4 3e-09 36.6 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 KFX86010.1 - 0.052 12.3 1.3 0.062 12.1 0.3 1.7 1 1 1 2 2 2 0 Fungal protein kinase DUF3813 PF12758.7 KFX86010.1 - 7.9 6.9 5.8 1 9.7 1.5 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3813) Rad52_Rad22 PF04098.15 KFX86014.1 - 4.8e-61 205.2 0.0 6.4e-61 204.8 0.0 1.2 1 0 0 1 1 1 1 Rad52/22 family double-strand break repair protein Fungal_trans PF04082.18 KFX86015.1 - 1.6e-09 37.2 0.0 3.1e-09 36.3 0.0 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain zf-H2C2_2 PF13465.6 KFX86017.1 - 3.8e-09 36.6 16.7 4.5e-05 23.7 3.0 3.6 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2 PF00096.26 KFX86017.1 - 4.2e-08 33.2 14.6 0.00047 20.5 4.5 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFX86017.1 - 0.00018 22.1 11.8 0.053 14.4 3.1 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFX86017.1 - 0.019 15.3 0.4 0.055 13.8 0.4 1.8 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 KFX86017.1 - 0.088 12.8 2.3 2.4 8.2 0.3 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger SpoIIIAH PF12685.7 KFX86017.1 - 3.3 7.5 6.4 0.38 10.6 1.6 1.8 2 1 0 2 2 2 0 SpoIIIAH-like protein PAS_9 PF13426.7 KFX86019.1 - 1.8e-09 37.7 0.0 3.5e-09 36.8 0.0 1.5 1 0 0 1 1 1 1 PAS domain CDC14 PF08045.11 KFX86022.1 - 9.4e-106 353.1 0.0 1.1e-105 352.8 0.0 1.0 1 0 0 1 1 1 1 Cell division control protein 14, SIN component Lambda_CIII PF02061.16 KFX86023.1 - 0.12 12.5 2.7 0.22 11.6 2.7 1.4 1 0 0 1 1 1 0 Lambda Phage CIII Ribosom_S12_S23 PF00164.25 KFX86026.1 - 1.2e-28 99.0 1.4 1.6e-28 98.6 1.4 1.1 1 0 0 1 1 1 1 Ribosomal protein S12/S23 EGF_3 PF12947.7 KFX86027.1 - 0.04 14.1 1.8 0.061 13.5 1.8 1.3 1 0 0 1 1 1 0 EGF domain Glyco_transf_15 PF01793.16 KFX86027.1 - 0.056 12.7 0.2 0.069 12.4 0.2 1.1 1 0 0 1 1 1 0 Glycolipid 2-alpha-mannosyltransferase DUF899 PF05988.12 KFX86029.1 - 5.1e-80 268.0 0.0 5.8e-80 267.9 0.0 1.0 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF899) AhpC-TSA PF00578.21 KFX86029.1 - 0.034 14.0 0.0 0.052 13.5 0.0 1.3 1 0 0 1 1 1 0 AhpC/TSA family Bacteriocin_IIc PF10439.9 KFX86034.1 - 0.2 11.8 17.5 0.79 9.9 6.7 2.9 3 0 0 3 3 3 0 Bacteriocin class II with double-glycine leader peptide Pro_CA PF00484.19 KFX86036.1 - 2e-30 106.2 0.1 2.4e-30 105.9 0.1 1.1 1 0 0 1 1 1 1 Carbonic anhydrase MWFE PF15879.5 KFX86037.1 - 1.3e-15 57.3 7.0 6.1e-13 48.7 0.2 2.1 1 1 1 2 2 2 2 NADH-ubiquinone oxidoreductase MWFE subunit Bax1-I PF01027.20 KFX86038.1 - 2.3 8.0 16.2 5.7 6.7 15.3 1.9 1 1 1 2 2 2 0 Inhibitor of apoptosis-promoting Bax1 DUF1218 PF06749.12 KFX86038.1 - 9.7 6.8 10.7 4.9 7.7 4.7 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF1218) AAA PF00004.29 KFX86040.1 - 1.6e-38 132.1 0.0 4.9e-38 130.5 0.0 1.7 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.10 KFX86040.1 - 7.9e-09 35.4 0.0 3.2e-08 33.4 0.0 2.0 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain AAA_lid_3 PF17862.1 KFX86040.1 - 5.5e-08 32.5 0.0 1.3e-07 31.3 0.0 1.7 1 0 0 1 1 1 1 AAA+ lid domain AAA_22 PF13401.6 KFX86040.1 - 2e-07 31.4 1.5 0.0001 22.6 0.1 3.1 1 1 0 2 2 2 1 AAA domain RuvB_N PF05496.12 KFX86040.1 - 9.1e-07 28.8 0.0 2.7e-05 24.0 0.0 2.3 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 KFX86040.1 - 0.00011 22.7 2.2 0.00073 20.0 2.2 2.5 1 1 0 1 1 1 1 AAA ATPase domain TIP49 PF06068.13 KFX86040.1 - 0.00022 20.5 0.0 0.00034 20.0 0.0 1.2 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_5 PF07728.14 KFX86040.1 - 0.00023 21.2 0.2 0.0021 18.1 0.0 2.5 3 1 0 3 3 2 1 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.17 KFX86040.1 - 0.0008 19.2 0.0 0.0013 18.5 0.0 1.3 1 0 0 1 1 1 1 IstB-like ATP binding protein Mg_chelatase PF01078.21 KFX86040.1 - 0.0015 18.0 0.1 0.003 17.0 0.1 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_14 PF13173.6 KFX86040.1 - 0.0026 17.8 0.0 0.01 15.8 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_2 PF07724.14 KFX86040.1 - 0.0026 17.9 0.0 0.0047 17.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_28 PF13521.6 KFX86040.1 - 0.0031 17.8 0.6 0.2 11.9 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.6 KFX86040.1 - 0.0064 16.1 0.2 0.049 13.2 0.0 2.3 3 0 0 3 3 3 1 AAA domain AAA_33 PF13671.6 KFX86040.1 - 0.008 16.3 0.1 0.014 15.5 0.1 1.7 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.6 KFX86040.1 - 0.015 15.8 0.0 0.033 14.7 0.0 1.7 1 1 0 1 1 1 0 AAA domain DUF815 PF05673.13 KFX86040.1 - 0.017 14.3 0.0 0.026 13.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_24 PF13479.6 KFX86040.1 - 0.025 14.3 0.0 0.04 13.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain TniB PF05621.11 KFX86040.1 - 0.026 13.9 0.0 1.9 7.9 0.0 2.4 1 1 1 2 2 2 0 Bacterial TniB protein Sigma54_activat PF00158.26 KFX86040.1 - 0.033 13.9 0.0 0.18 11.5 0.0 2.2 1 1 2 3 3 3 0 Sigma-54 interaction domain AAA_7 PF12775.7 KFX86040.1 - 0.035 13.6 0.0 0.093 12.2 0.0 1.7 1 0 0 1 1 1 0 P-loop containing dynein motor region NACHT PF05729.12 KFX86040.1 - 0.038 13.9 0.0 0.1 12.5 0.0 1.7 1 1 0 1 1 1 0 NACHT domain PhoH PF02562.16 KFX86040.1 - 0.06 12.8 0.0 0.15 11.5 0.0 1.6 1 0 0 1 1 1 0 PhoH-like protein AAA_19 PF13245.6 KFX86040.1 - 0.06 13.7 0.1 0.1 13.0 0.1 1.6 1 1 0 1 1 1 0 AAA domain ABC_tran PF00005.27 KFX86040.1 - 0.067 13.7 0.0 0.13 12.8 0.0 1.5 1 1 0 1 1 1 0 ABC transporter AAA_30 PF13604.6 KFX86040.1 - 0.069 12.9 0.1 0.17 11.6 0.1 1.7 1 1 0 1 1 1 0 AAA domain Guanylate_kin PF00625.21 KFX86040.1 - 0.13 12.0 0.0 0.45 10.2 0.0 1.9 1 1 0 1 1 1 0 Guanylate kinase ATPase PF06745.13 KFX86040.1 - 0.14 11.5 0.1 1.2 8.5 0.0 2.0 1 1 1 2 2 2 0 KaiC RNA_helicase PF00910.22 KFX86040.1 - 0.14 12.6 0.0 0.27 11.6 0.0 1.5 1 0 0 1 1 1 0 RNA helicase SRPRB PF09439.10 KFX86040.1 - 0.17 11.3 0.0 0.29 10.6 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit NB-ARC PF00931.22 KFX86040.1 - 0.23 10.6 0.1 1.3 8.1 0.0 1.9 2 0 0 2 2 2 0 NB-ARC domain ATPase_2 PF01637.18 KFX86040.1 - 0.23 11.3 0.0 0.84 9.5 0.0 1.9 2 1 0 2 2 2 0 ATPase domain predominantly from Archaea Ribosomal_S17 PF00366.20 KFX86041.1 - 1.3e-20 73.3 0.9 1.3e-20 73.3 0.9 1.4 2 0 0 2 2 2 1 Ribosomal protein S17 WSN PF02206.18 KFX86041.1 - 0.00083 19.2 0.0 0.0016 18.3 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function ADH_N PF08240.12 KFX86043.1 - 1.8e-18 66.4 0.7 4.5e-18 65.1 0.2 1.9 2 1 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_N_assoc PF13823.6 KFX86043.1 - 0.0012 18.8 3.0 0.0042 17.0 3.0 2.0 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-associated Glu_dehyd_C PF16912.5 KFX86043.1 - 0.088 12.3 0.0 0.14 11.6 0.0 1.3 1 0 0 1 1 1 0 Glucose dehydrogenase C-terminus Methyltransf_23 PF13489.6 KFX86046.1 - 2.4e-14 53.5 0.0 3.4e-14 53.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KFX86046.1 - 4.9e-10 40.0 0.0 3e-09 37.5 0.0 2.2 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 KFX86046.1 - 1.5e-06 28.7 0.0 2.8e-06 27.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KFX86046.1 - 0.0003 20.2 0.0 0.77 9.0 0.0 2.6 3 0 0 3 3 3 2 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.6 KFX86046.1 - 0.00094 19.0 0.0 1.4 8.7 0.0 2.2 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_12 PF08242.12 KFX86046.1 - 0.0016 19.1 0.0 0.011 16.4 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Met_10 PF02475.16 KFX86046.1 - 0.025 14.3 0.0 0.042 13.6 0.0 1.3 1 0 0 1 1 1 0 Met-10+ like-protein FtsJ PF01728.19 KFX86046.1 - 0.043 13.9 0.1 0.06 13.5 0.1 1.4 1 1 0 1 1 1 0 FtsJ-like methyltransferase PrmA PF06325.13 KFX86046.1 - 0.17 11.2 0.0 0.56 9.5 0.0 1.7 2 0 0 2 2 2 0 Ribosomal protein L11 methyltransferase (PrmA) ATP-synt_DE_N PF02823.16 KFX86050.1 - 6.3e-14 51.6 0.1 1e-13 51.0 0.1 1.3 1 0 0 1 1 1 1 ATP synthase, Delta/Epsilon chain, beta-sandwich domain TPR_2 PF07719.17 KFX86053.1 - 9.7e-25 84.7 2.7 7.1e-05 22.6 0.1 5.4 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_1 PF00515.28 KFX86053.1 - 6.5e-22 76.4 6.8 4.7e-06 26.2 0.0 5.4 5 1 0 5 5 5 4 Tetratricopeptide repeat TPR_8 PF13181.6 KFX86053.1 - 3.1e-15 55.1 4.7 0.0031 17.6 0.1 5.3 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_11 PF13414.6 KFX86053.1 - 1.1e-13 50.6 3.4 1.2e-05 24.9 0.0 4.7 4 1 1 5 5 5 3 TPR repeat TPR_16 PF13432.6 KFX86053.1 - 1.2e-13 51.4 0.1 0.0014 19.3 0.0 4.2 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_12 PF13424.6 KFX86053.1 - 1.9e-13 50.5 6.9 0.0002 21.6 2.6 5.0 3 2 2 5 5 5 4 Tetratricopeptide repeat TPR_19 PF14559.6 KFX86053.1 - 1.2e-11 45.0 3.0 2.5e-06 27.9 1.6 3.4 2 1 2 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.6 KFX86053.1 - 1.3e-11 44.3 1.4 0.031 15.1 0.3 4.4 3 1 1 4 4 4 4 Tetratricopeptide repeat TPR_7 PF13176.6 KFX86053.1 - 1.1e-10 40.7 2.4 0.019 15.0 0.1 4.6 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_17 PF13431.6 KFX86053.1 - 2e-09 37.2 0.0 0.05 14.0 0.0 5.3 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_10 PF13374.6 KFX86053.1 - 2.1e-09 37.0 5.1 0.0057 16.5 0.3 4.6 4 0 0 4 4 4 2 Tetratricopeptide repeat ANAPC3 PF12895.7 KFX86053.1 - 3.1e-08 33.7 1.3 0.0052 17.0 0.3 3.2 2 1 1 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.6 KFX86053.1 - 2e-07 31.0 1.4 0.00028 21.0 0.4 2.9 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_MalT PF17874.1 KFX86053.1 - 0.00029 20.3 1.5 0.0015 18.0 1.4 2.1 1 1 1 2 2 2 1 MalT-like TPR region SHNi-TPR PF10516.9 KFX86053.1 - 0.00032 20.1 2.2 0.25 10.8 0.0 2.8 3 0 0 3 3 2 2 SHNi-TPR TPR_15 PF13429.6 KFX86053.1 - 0.00059 19.1 0.9 0.015 14.5 1.6 2.5 1 1 1 2 2 2 1 Tetratricopeptide repeat Phage_CP76 PF06892.11 KFX86053.1 - 0.0016 18.0 0.0 0.003 17.1 0.0 1.4 1 0 0 1 1 1 1 Phage regulatory protein CII (CP76) DUF3856 PF12968.7 KFX86053.1 - 0.0021 18.1 1.2 0.65 10.1 0.0 3.3 3 1 0 3 3 2 1 Domain of Unknown Function (DUF3856) TAF1_subA PF14929.6 KFX86053.1 - 0.007 15.8 0.4 0.013 14.9 0.2 1.4 1 1 0 1 1 1 1 TAF RNA Polymerase I subunit A preATP-grasp_3 PF18301.1 KFX86053.1 - 0.021 15.1 0.2 0.087 13.1 0.2 1.9 2 0 0 2 2 2 0 pre ATP-grasp 3 domain MIT PF04212.18 KFX86053.1 - 0.024 14.7 1.7 2.5 8.2 0.1 3.4 3 0 0 3 3 3 0 MIT (microtubule interacting and transport) domain TPR_21 PF09976.9 KFX86053.1 - 0.031 14.0 3.2 1.6 8.4 0.5 2.6 1 1 1 2 2 2 0 Tetratricopeptide repeat-like domain HrpB1_HrpK PF09613.10 KFX86053.1 - 0.037 13.7 0.4 0.13 11.9 0.4 1.9 1 1 1 2 2 2 0 Bacterial type III secretion protein (HrpB1_HrpK) Sel1 PF08238.12 KFX86053.1 - 0.056 14.1 2.2 0.31 11.8 0.1 2.9 3 0 0 3 3 2 0 Sel1 repeat MAS20 PF02064.15 KFX86053.1 - 0.069 13.2 0.2 8.6 6.5 0.1 2.8 2 1 1 3 3 3 0 MAS20 protein import receptor TPR_6 PF13174.6 KFX86053.1 - 0.21 12.3 12.8 5.2 7.9 0.5 5.3 7 0 0 7 7 5 0 Tetratricopeptide repeat Helicase_C PF00271.31 KFX86057.1 - 0.00013 22.3 0.0 0.00021 21.6 0.0 1.3 1 0 0 1 1 1 1 Helicase conserved C-terminal domain RecQ_Zn_bind PF16124.5 KFX86057.1 - 0.016 15.9 1.9 0.016 15.9 1.9 2.6 3 1 0 3 3 3 0 RecQ zinc-binding DUF469 PF04320.14 KFX86057.1 - 0.087 13.7 0.4 2.8 8.9 0.0 3.0 3 0 0 3 3 3 0 Protein with unknown function (DUF469) SH3_1 PF00018.28 KFX86058.1 - 4.1e-05 23.1 0.0 4.1e-05 23.1 0.0 1.9 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.6 KFX86058.1 - 0.023 14.6 0.0 0.06 13.2 0.0 1.8 1 0 0 1 1 1 0 Variant SH3 domain Abhydro_lipase PF04083.16 KFX86060.1 - 1e-19 69.8 0.0 2.3e-19 68.7 0.0 1.6 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Abhydrolase_1 PF00561.20 KFX86060.1 - 2.1e-07 30.8 0.1 4.7e-07 29.7 0.1 1.6 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KFX86060.1 - 0.00093 18.5 0.0 0.0019 17.5 0.0 1.5 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_3 PF07859.13 KFX86062.1 - 6.9e-22 78.3 0.0 1.1e-21 77.6 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 KFX86062.1 - 2.8e-20 72.5 0.0 3.4e-20 72.2 0.0 1.1 1 0 0 1 1 1 1 Steryl acetyl hydrolase Peptidase_S9 PF00326.21 KFX86062.1 - 0.059 12.8 0.0 0.82 9.1 0.0 2.1 2 0 0 2 2 2 0 Prolyl oligopeptidase family Esterase_phd PF10503.9 KFX86062.1 - 0.093 12.2 0.1 0.19 11.2 0.1 1.4 1 0 0 1 1 1 0 Esterase PHB depolymerase Chlorophyllase2 PF12740.7 KFX86062.1 - 0.16 10.8 0.0 0.29 10.0 0.0 1.3 1 0 0 1 1 1 0 Chlorophyllase enzyme Glyco_trans_1_4 PF13692.6 KFX86064.1 - 1.8e-06 28.4 0.0 3.7e-06 27.4 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glycos_transf_1 PF00534.20 KFX86064.1 - 0.00058 19.4 0.0 0.001 18.7 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 APH PF01636.23 KFX86065.1 - 5.8e-14 52.6 0.0 8.2e-14 52.1 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KFX86065.1 - 0.075 12.6 0.0 0.12 11.9 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase SlyX PF04102.12 KFX86072.1 - 0.0015 19.1 0.2 0.0035 17.9 0.2 1.6 1 0 0 1 1 1 1 SlyX CENP-Q PF13094.6 KFX86072.1 - 0.0094 16.2 0.1 0.013 15.7 0.1 1.3 1 0 0 1 1 1 1 CENP-Q, a CENPA-CAD centromere complex subunit DUF641 PF04859.12 KFX86072.1 - 0.051 13.9 0.4 0.089 13.1 0.4 1.4 1 0 0 1 1 1 0 Plant protein of unknown function (DUF641) Atg14 PF10186.9 KFX86072.1 - 0.095 11.8 0.4 0.14 11.2 0.4 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 End3 PF12761.7 KFX86072.1 - 0.12 12.5 0.1 0.2 11.8 0.1 1.3 1 0 0 1 1 1 0 Actin cytoskeleton-regulatory complex protein END3 MPS2 PF17060.5 KFX86072.1 - 0.18 11.0 0.1 0.24 10.6 0.1 1.1 1 0 0 1 1 1 0 Monopolar spindle protein 2 Chibby PF14645.6 KFX86072.1 - 0.19 12.2 0.0 0.3 11.5 0.0 1.3 1 0 0 1 1 1 0 Chibby family ATG16 PF08614.11 KFX86074.1 - 0.24 11.6 3.2 0.2 11.9 1.0 1.9 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) WD40 PF00400.32 KFX86077.1 - 6.2e-07 30.0 0.0 0.71 10.8 0.0 4.1 4 0 0 4 4 4 3 WD domain, G-beta repeat Zip PF02535.22 KFX86080.1 - 4.7e-07 29.3 0.4 7e-07 28.8 0.4 1.3 1 0 0 1 1 1 1 ZIP Zinc transporter DctQ PF04290.12 KFX86080.1 - 0.0024 17.8 0.8 0.031 14.2 1.8 1.9 2 0 0 2 2 2 1 Tripartite ATP-independent periplasmic transporters, DctQ component DUF3094 PF11293.8 KFX86080.1 - 0.37 10.5 1.4 1.3 8.8 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3094) TMEM154 PF15102.6 KFX86086.1 - 0.048 13.6 0.0 0.058 13.3 0.0 1.3 1 1 0 1 1 1 0 TMEM154 protein family TrbC PF04956.13 KFX86086.1 - 0.066 13.4 0.7 0.099 12.9 0.7 1.2 1 0 0 1 1 1 0 TrbC/VIRB2 family Alpha_GJ PF03229.13 KFX86086.1 - 0.067 13.8 5.0 0.095 13.3 5.0 1.3 1 0 0 1 1 1 0 Alphavirus glycoprotein J Med3 PF11593.8 KFX86086.1 - 1.7 7.7 7.7 1.9 7.6 7.7 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal MGC-24 PF05283.11 KFX86086.1 - 9.4 6.7 8.4 7.9 6.9 7.5 1.4 1 1 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin ADH_zinc_N PF00107.26 KFX86089.1 - 6.1e-09 35.9 0.0 1.2e-08 35.0 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KFX86089.1 - 0.0027 17.6 0.0 0.0053 16.6 0.0 1.4 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain MFS_1 PF07690.16 KFX86090.1 - 1e-21 77.3 12.6 1.2e-21 77.1 12.6 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KFX86090.1 - 4.2e-15 55.5 0.3 4.4e-15 55.5 0.3 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter TRI12 PF06609.13 KFX86090.1 - 4.8e-07 28.6 0.4 5.1e-07 28.5 0.4 1.0 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_2 PF13347.6 KFX86090.1 - 0.0026 16.4 7.1 0.0036 15.9 7.2 1.2 1 1 0 1 1 1 1 MFS/sugar transport protein Exo_endo_phos PF03372.23 KFX86093.1 - 0.0032 17.0 0.1 0.0085 15.6 0.0 1.7 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family WD40 PF00400.32 KFX86097.1 - 5.4e-10 39.7 3.3 5.4e-06 27.0 0.0 4.7 4 0 0 4 4 4 2 WD domain, G-beta repeat zf-C2H2_2 PF12756.7 KFX86100.1 - 0.1 13.0 0.3 0.17 12.2 0.3 1.2 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) DUF629 PF04780.12 KFX86100.1 - 0.13 10.8 0.0 0.18 10.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF629) MFS_1 PF07690.16 KFX86103.1 - 2.1e-35 122.3 24.4 3.1e-35 121.8 24.4 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Trp_oprn_chp PF09534.10 KFX86103.1 - 2.2 8.0 7.6 0.21 11.4 2.1 2.1 2 1 0 2 2 2 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) Zn_clus PF00172.18 KFX86104.1 - 3.1e-06 27.2 3.0 3.1e-06 27.2 3.0 2.0 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RPN7 PF10602.9 KFX86106.1 - 1.8e-43 148.2 0.6 3.6e-43 147.3 0.6 1.5 1 0 0 1 1 1 1 26S proteasome subunit RPN7 PCI PF01399.27 KFX86106.1 - 1.1e-13 51.6 0.7 6.2e-13 49.2 0.0 2.5 3 0 0 3 3 3 1 PCI domain TPR_2 PF07719.17 KFX86106.1 - 0.011 15.8 5.1 1.4 9.2 0.0 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF3808 PF10300.9 KFX86106.1 - 0.049 12.4 1.7 2.6 6.7 0.2 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3808) TPR_1 PF00515.28 KFX86106.1 - 0.18 11.7 7.9 3.7 7.5 0.6 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat Mito_carr PF00153.27 KFX86109.1 - 9.3e-17 60.7 0.1 1.8e-16 59.9 0.1 1.4 1 0 0 1 1 1 1 Mitochondrial carrier protein LPMO_10 PF03067.15 KFX86109.1 - 2.5e-07 31.6 1.8 3.2e-07 31.2 1.8 1.2 1 0 0 1 1 1 1 Lytic polysaccharide mono-oxygenase, cellulose-degrading CDC45 PF02724.14 KFX86113.1 - 0.13 10.5 18.7 0.24 9.6 18.7 1.4 1 0 0 1 1 1 0 CDC45-like protein DUF4813 PF16072.5 KFX86114.1 - 0.11 12.2 2.0 0.1 12.3 2.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4813) Aim19 PF10315.9 KFX86118.1 - 2.1e-05 24.8 0.7 3e-05 24.3 0.7 1.4 1 1 0 1 1 1 1 Altered inheritance of mitochondria protein 19 NADH-u_ox-rdase PF10785.9 KFX86118.1 - 0.12 13.0 0.2 0.2 12.4 0.2 1.4 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase complex I, 21 kDa subunit Y_phosphatase2 PF03162.13 KFX86119.1 - 1.1e-47 161.6 0.0 1.6e-47 161.2 0.0 1.2 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3 PF13350.6 KFX86119.1 - 1.1e-09 38.7 0.0 3.3e-09 37.1 0.0 1.8 1 1 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase PF00102.27 KFX86119.1 - 0.0038 16.8 0.1 0.0056 16.3 0.1 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.20 KFX86119.1 - 0.017 14.9 0.0 0.026 14.4 0.0 1.3 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain BDM PF10684.9 KFX86121.1 - 0.77 10.2 2.2 8.7 6.8 0.1 2.1 1 1 1 2 2 2 0 Putative biofilm-dependent modulation protein Amidohydro_1 PF01979.20 KFX86123.1 - 3.2e-08 33.3 0.2 3.8e-08 33.0 0.2 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 KFX86123.1 - 2.5e-06 27.2 0.1 3.8e-06 26.6 0.1 1.2 1 0 0 1 1 1 1 Amidohydrolase family Epimerase PF01370.21 KFX86130.1 - 7.7e-12 45.2 0.1 1.1e-05 25.1 0.1 2.1 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 KFX86130.1 - 2.5e-11 43.8 0.1 3.6e-11 43.3 0.1 1.3 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 KFX86130.1 - 1e-08 35.0 1.4 1.2e-08 34.9 0.2 1.6 2 0 0 2 2 2 1 NmrA-like family NAD_binding_4 PF07993.12 KFX86130.1 - 2.9e-05 23.4 0.0 6.9e-05 22.1 0.0 1.7 2 1 0 2 2 2 1 Male sterility protein 3Beta_HSD PF01073.19 KFX86130.1 - 4.3e-05 22.6 0.0 0.0026 16.8 0.1 2.1 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 KFX86130.1 - 0.00037 20.0 0.0 0.01 15.2 0.0 2.2 2 1 0 2 2 2 1 GDP-mannose 4,6 dehydratase Semialdhyde_dh PF01118.24 KFX86130.1 - 0.013 15.9 0.0 0.026 15.0 0.0 1.5 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Polysacc_synt_2 PF02719.15 KFX86130.1 - 0.029 13.5 0.1 0.046 12.8 0.1 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein PglD_N PF17836.1 KFX86130.1 - 0.038 14.6 0.3 0.16 12.6 0.1 2.2 2 1 0 2 2 2 0 PglD N-terminal domain OATP PF03137.20 KFX86137.1 - 0.23 9.7 0.1 0.32 9.2 0.1 1.1 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family GluRS_N PF18466.1 KFX86140.1 - 0.069 13.6 0.4 0.22 11.9 0.4 2.0 1 0 0 1 1 1 0 Glutamate--tRNA ligase N-terminal domain PX PF00787.24 KFX86141.1 - 6.8e-14 51.8 0.0 9.8e-14 51.3 0.0 1.2 1 0 0 1 1 1 1 PX domain Spt5-NGN PF03439.13 KFX86143.1 - 0.057 13.3 0.0 0.1 12.5 0.0 1.4 1 0 0 1 1 1 0 Early transcription elongation factor of RNA pol II, NGN section DHDPS PF00701.22 KFX86144.1 - 2.4e-25 88.8 0.0 3.1e-25 88.5 0.0 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family Mito_carr PF00153.27 KFX86149.1 - 8.5e-43 144.2 0.2 4.7e-24 84.1 0.0 2.0 2 0 0 2 2 2 2 Mitochondrial carrier protein NMT1_2 PF13379.6 KFX86150.1 - 0.048 13.3 0.0 0.052 13.2 0.0 1.0 1 0 0 1 1 1 0 NMT1-like family 1-cysPrx_C PF10417.9 KFX86150.1 - 0.086 12.7 1.2 0.16 11.8 1.2 1.4 1 0 0 1 1 1 0 C-terminal domain of 1-Cys peroxiredoxin Bac_rhamnosid_C PF17390.2 KFX86151.1 - 1e-25 89.3 0.1 1.3e-25 88.9 0.1 1.1 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase C-terminal domain Bac_rhamnosid6H PF17389.2 KFX86151.1 - 0.0028 17.0 0.3 0.0035 16.7 0.3 1.1 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain MBD PF01429.19 KFX86151.1 - 0.064 13.0 0.0 0.095 12.4 0.0 1.2 1 0 0 1 1 1 0 Methyl-CpG binding domain Yae1_N PF09811.9 KFX86153.1 - 1.2e-11 44.1 1.1 2.9e-11 42.9 1.1 1.7 1 0 0 1 1 1 1 Essential protein Yae1, N terminal Nuclease_act PF08133.11 KFX86153.1 - 0.024 14.7 0.2 0.26 11.5 0.0 2.7 2 0 0 2 2 2 0 Anticodon nuclease activator family HisKA_4TM PF16926.5 KFX86153.1 - 0.068 12.7 0.2 0.12 11.9 0.2 1.3 1 0 0 1 1 1 0 Archaeal 4TM region of histidine kinase GPI-anchored PF10342.9 KFX86156.1 - 1.2e-19 70.8 0.3 1.2e-19 70.8 0.3 2.4 2 1 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Macoilin PF09726.9 KFX86156.1 - 0.3 9.6 1.6 0.33 9.5 1.6 1.0 1 0 0 1 1 1 0 Macoilin family CPSF100_C PF13299.6 KFX86156.1 - 1.8 8.7 3.7 2.2 8.4 3.7 1.2 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal DREPP PF05558.12 KFX86156.1 - 1.9 8.3 9.0 2.8 7.8 9.0 1.2 1 0 0 1 1 1 0 DREPP plasma membrane polypeptide SOG2 PF10428.9 KFX86156.1 - 2.3 7.3 14.2 2.5 7.2 14.2 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein SAPS PF04499.15 KFX86156.1 - 5.8 5.6 6.0 6.5 5.4 6.0 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein AF-4 PF05110.13 KFX86156.1 - 8.2 4.4 17.5 9.4 4.2 17.5 1.0 1 0 0 1 1 1 0 AF-4 proto-oncoprotein UBX PF00789.20 KFX86160.1 - 3e-07 30.5 0.0 7e-07 29.4 0.0 1.6 1 0 0 1 1 1 1 UBX domain DARPP-32 PF05395.12 KFX86160.1 - 0.0014 18.9 5.5 0.0024 18.1 5.5 1.3 1 0 0 1 1 1 1 Protein phosphatase inhibitor 1/DARPP-32 PepSY_TM PF03929.16 KFX86160.1 - 0.1 12.3 0.3 0.24 11.1 0.0 1.6 2 0 0 2 2 2 0 PepSY-associated TM region Trypan_PARP PF05887.11 KFX86160.1 - 0.1 12.6 6.6 0.18 11.8 6.6 1.4 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) ANAPC4_WD40 PF12894.7 KFX86163.1 - 0.0091 16.3 0.0 0.023 15.0 0.0 1.6 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain NAD_binding_6 PF08030.12 KFX86171.1 - 0.0052 16.9 0.0 0.006 16.7 0.0 1.0 1 0 0 1 1 1 1 Ferric reductase NAD binding domain ACOX PF01756.19 KFX86180.1 - 1.5e-43 148.4 0.1 8.7e-43 146.0 0.0 1.9 2 0 0 2 2 2 1 Acyl-CoA oxidase p450 PF00067.22 KFX86186.1 - 5.2e-44 150.7 0.0 7.3e-44 150.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Tn916-Xis PF09035.10 KFX86186.1 - 0.15 12.3 0.0 0.32 11.2 0.0 1.5 1 0 0 1 1 1 0 Excisionase from transposon Tn916 EF-hand_7 PF13499.6 KFX86189.1 - 6.3e-12 45.8 0.6 4.3e-08 33.5 0.1 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 KFX86189.1 - 3.4e-09 35.9 0.4 0.014 15.3 0.1 3.4 3 0 0 3 3 3 2 EF-hand domain EF-hand_9 PF14658.6 KFX86189.1 - 1.2e-08 35.1 0.0 0.0081 16.5 0.0 2.4 2 1 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.32 KFX86189.1 - 2.4e-08 33.0 0.1 0.026 14.1 0.0 3.6 3 1 0 3 3 3 2 EF hand EF-hand_8 PF13833.6 KFX86189.1 - 3.3e-06 26.9 0.1 7.2e-05 22.5 0.1 2.7 3 0 0 3 3 3 1 EF-hand domain pair DUF3216 PF11505.8 KFX86189.1 - 0.066 13.4 0.0 0.12 12.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3216) PAPS_reduct PF01507.19 KFX86192.1 - 2.8e-25 89.4 0.0 4.1e-25 88.8 0.0 1.3 1 0 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family HA PF03457.14 KFX86192.1 - 0.032 14.5 0.9 3.5 8.0 0.2 2.5 2 0 0 2 2 2 0 Helicase associated domain PHC2_SAM_assoc PF16616.5 KFX86197.1 - 0.019 15.8 3.7 0.043 14.6 3.7 1.6 1 1 0 1 1 1 0 Unstructured region on Polyhomeotic-like protein 1 and 2 adh_short_C2 PF13561.6 KFX86203.1 - 5.8e-33 114.4 0.0 7.2e-33 114.1 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KFX86203.1 - 1.1e-24 86.9 0.0 1.4e-24 86.6 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KFX86203.1 - 1.9e-05 24.7 0.0 3.5e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 KR domain THF_DHG_CYH_C PF02882.19 KFX86203.1 - 0.0039 16.5 0.0 0.0071 15.7 0.0 1.4 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain NAD_binding_7 PF13241.6 KFX86203.1 - 0.0087 16.5 0.0 0.019 15.4 0.0 1.5 2 0 0 2 2 2 1 Putative NAD(P)-binding Eno-Rase_NADH_b PF12242.8 KFX86203.1 - 0.012 15.4 0.3 0.021 14.5 0.3 1.4 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Epimerase PF01370.21 KFX86203.1 - 0.082 12.4 0.0 0.23 10.9 0.0 1.8 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family ADH_zinc_N PF00107.26 KFX86206.1 - 7.2e-17 61.6 0.0 1.1e-16 61.0 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KFX86206.1 - 2.5e-10 40.2 3.2 4.4e-10 39.4 3.2 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 KFX86206.1 - 5.8e-06 27.4 0.0 1.1e-05 26.5 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 KFX86206.1 - 0.0012 18.2 0.2 0.0019 17.5 0.2 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.19 KFX86206.1 - 0.0054 16.1 0.3 0.0087 15.4 0.3 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_10 PF13460.6 KFX86209.1 - 5.4e-22 78.6 0.8 6.8e-22 78.2 0.8 1.1 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KFX86209.1 - 2.5e-05 23.9 0.0 3.3e-05 23.5 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.13 KFX86209.1 - 0.044 13.3 0.1 0.23 11.0 0.0 2.0 2 1 0 2 2 2 0 NmrA-like family Ldh_1_N PF00056.23 KFX86209.1 - 0.064 13.3 0.0 0.13 12.3 0.0 1.5 1 1 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain adh_short PF00106.25 KFX86216.1 - 1e-18 67.5 0.2 1.3e-18 67.2 0.2 1.0 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KFX86216.1 - 8.7e-16 58.2 0.2 1e-15 58.0 0.2 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KFX86216.1 - 3.3e-08 33.6 0.1 4.1e-08 33.4 0.1 1.0 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KFX86216.1 - 0.00074 19.0 0.1 0.00094 18.7 0.1 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF572 PF04502.13 KFX86219.1 - 1.2e-06 28.4 0.0 1.3e-06 28.3 0.0 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF572) Pkinase PF00069.25 KFX86220.1 - 0.0065 15.9 0.0 0.014 14.8 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_C PF00433.24 KFX86222.1 - 0.0042 17.7 0.1 0.0082 16.8 0.1 1.5 1 0 0 1 1 1 1 Protein kinase C terminal domain LDB19 PF13002.7 KFX86224.1 - 0.0015 18.3 0.2 0.0023 17.7 0.2 1.2 1 0 0 1 1 1 1 Arrestin_N terminal like Ribosomal_L6e PF01159.19 KFX86227.1 - 1.1 9.8 5.6 2.4 8.7 5.6 1.4 1 0 0 1 1 1 0 Ribosomal protein L6e Cytochrom_B558a PF05038.13 KFX86231.1 - 0.033 13.8 0.1 0.1 12.2 0.0 1.8 2 0 0 2 2 2 0 Cytochrome Cytochrome b558 alpha-subunit MFS_1 PF07690.16 KFX86234.1 - 3.5e-07 29.5 16.2 6.4e-06 25.3 17.4 1.9 1 1 0 1 1 1 1 Major Facilitator Superfamily DUF2530 PF10745.9 KFX86234.1 - 1.7 8.9 6.2 0.89 9.8 0.5 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF2530) DUF5455 PF17537.2 KFX86234.1 - 2.9 8.3 6.5 11 6.5 1.6 2.6 2 0 0 2 2 2 0 Family of unknown function (DUF5455) NACHT PF05729.12 KFX86235.1 - 5.6e-09 36.1 0.1 1.2e-08 35.1 0.1 1.6 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 KFX86235.1 - 2.9e-05 24.5 0.1 0.00014 22.3 0.1 2.0 1 1 0 1 1 1 1 AAA ATPase domain KAP_NTPase PF07693.14 KFX86235.1 - 6.7e-05 22.3 0.8 0.11 11.7 0.1 2.5 3 0 0 3 3 3 2 KAP family P-loop domain WLM PF08325.10 KFX86236.1 - 6e-29 101.5 0.9 1.8e-28 99.9 0.9 1.7 1 1 0 1 1 1 1 WLM domain DUF45 PF01863.17 KFX86236.1 - 3.4e-08 33.8 1.0 6.3e-08 32.9 1.0 1.4 1 0 0 1 1 1 1 Protein of unknown function DUF45 MIR PF02815.19 KFX86236.1 - 0.031 14.1 0.1 0.045 13.6 0.1 1.2 1 0 0 1 1 1 0 MIR domain DUF1713 PF08213.11 KFX86239.1 - 1.7e-12 47.0 20.4 1.7e-12 47.0 20.4 1.6 2 0 0 2 2 2 1 Mitochondrial domain of unknown function (DUF1713) UBA PF00627.31 KFX86240.1 - 1.9e-05 24.4 0.1 2.9e-05 23.9 0.1 1.3 1 0 0 1 1 1 1 UBA/TS-N domain HOIP-UBA PF16678.5 KFX86240.1 - 0.045 13.7 0.0 0.074 13.1 0.0 1.3 1 0 0 1 1 1 0 HOIP UBA domain pair FoP_duplication PF13865.6 KFX86244.1 - 4.3 8.0 6.7 4.7 7.8 6.7 1.1 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 Ank_2 PF12796.7 KFX86247.1 - 1e-80 266.4 0.0 2.2e-16 60.2 0.0 5.5 2 1 5 7 7 7 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KFX86247.1 - 1e-58 195.0 0.1 5.7e-11 42.7 0.0 7.9 1 1 8 9 9 9 9 Ankyrin repeats (many copies) Ank PF00023.30 KFX86247.1 - 3.8e-50 166.2 0.1 0.00014 22.1 0.0 9.4 9 0 0 9 9 9 8 Ankyrin repeat Ank_3 PF13606.6 KFX86247.1 - 1.8e-42 138.4 0.7 0.00025 21.2 0.0 9.2 9 0 0 9 9 9 7 Ankyrin repeat Ank_5 PF13857.6 KFX86247.1 - 9e-38 127.9 0.1 1.9e-08 34.4 0.0 5.7 4 1 1 5 5 5 5 Ankyrin repeats (many copies) P_C PF06640.11 KFX86247.1 - 0.0016 18.6 0.6 4.8 7.3 0.0 4.1 2 1 1 4 4 4 1 P protein C-terminus VBS PF08913.10 KFX86247.1 - 0.012 16.1 0.0 2.4 8.6 0.0 3.3 1 1 3 4 4 4 0 Vinculin Binding Site Phosphatase PF15698.5 KFX86247.1 - 0.027 13.6 0.0 22 4.1 0.0 3.6 3 1 1 4 4 4 0 Phosphatase PsaA_PsaB PF00223.19 KFX86247.1 - 0.044 12.0 0.0 0.059 11.6 0.0 1.1 1 0 0 1 1 1 0 Photosystem I psaA/psaB protein HTH_21 PF13276.6 KFX86247.1 - 0.15 12.2 0.0 2.1e+02 2.2 0.0 4.5 5 1 1 6 6 6 0 HTH-like domain cNMP_binding PF00027.29 KFX86248.1 - 9.9e-41 137.7 0.0 6.7e-20 71.0 0.0 2.3 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain PTH2 PF01981.16 KFX86250.1 - 2.5e-43 147.1 0.1 2.9e-43 146.9 0.1 1.1 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase PTH2 EHN PF06441.12 KFX86255.1 - 3e-27 95.1 0.1 4.3e-27 94.6 0.1 1.2 1 0 0 1 1 1 1 Epoxide hydrolase N terminus Ycf66_N PF07444.11 KFX86256.1 - 0.086 13.0 0.1 0.086 13.0 0.1 1.8 2 0 0 2 2 2 0 Ycf66 protein N-terminus Spindle_Spc25 PF08234.12 KFX86264.1 - 3.1e-24 85.0 0.4 8.8e-24 83.5 0.0 2.0 3 0 0 3 3 3 1 Chromosome segregation protein Spc25 Macoilin PF09726.9 KFX86264.1 - 0.046 12.3 6.2 0.056 12.0 6.2 1.0 1 0 0 1 1 1 0 Macoilin family PRTP PF01366.18 KFX86264.1 - 0.58 8.1 4.7 0.73 7.8 4.7 1.1 1 0 0 1 1 1 0 Herpesvirus processing and transport protein APG6_N PF17675.1 KFX86264.1 - 1.6 9.2 9.9 3.1 8.3 9.9 1.4 1 0 0 1 1 1 0 Apg6 coiled-coil region Med21 PF11221.8 KFX86264.1 - 3.1 8.0 8.7 9.2 6.5 8.8 1.7 1 1 0 1 1 1 0 Subunit 21 of Mediator complex DUF5522 PF17653.1 KFX86267.1 - 0.077 13.0 2.8 0.15 12.0 2.8 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5522) RSRP PF17069.5 KFX86269.1 - 1.2 8.6 35.6 0.12 11.9 3.9 2.2 2 0 0 2 2 2 0 Arginine/Serine-Rich protein 1 MRI PF15325.6 KFX86269.1 - 5 8.3 13.3 0.77 10.9 1.0 3.1 3 0 0 3 3 3 0 Modulator of retrovirus infection Trimer_CC PF08954.11 KFX86270.1 - 0.054 13.1 0.1 0.15 11.6 0.1 1.7 1 0 0 1 1 1 0 Trimerisation motif MFS_1 PF07690.16 KFX86272.1 - 3.2e-07 29.6 32.0 3.2e-07 29.6 32.0 2.5 2 1 0 2 2 2 1 Major Facilitator Superfamily Peptidase_U4 PF03419.13 KFX86272.1 - 5.8 6.1 12.1 8.5 5.6 11.0 1.9 1 1 1 2 2 2 0 Sporulation factor SpoIIGA Syntaxin PF00804.25 KFX86276.1 - 0.0018 18.0 1.3 0.003 17.3 1.3 1.3 1 0 0 1 1 1 1 Syntaxin HALZ PF02183.18 KFX86276.1 - 0.0054 16.9 5.2 0.0054 16.9 5.2 2.8 3 0 0 3 3 3 1 Homeobox associated leucine zipper GPS2_interact PF15784.5 KFX86276.1 - 0.027 14.9 2.7 0.04 14.4 2.0 1.8 1 1 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain Fez1 PF06818.15 KFX86276.1 - 0.042 14.3 6.0 0.041 14.3 4.9 1.4 2 0 0 2 2 1 0 Fez1 DUF724 PF05266.14 KFX86276.1 - 0.057 13.2 6.7 0.099 12.5 6.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF724) DUF4407 PF14362.6 KFX86276.1 - 0.069 12.5 3.9 0.12 11.7 3.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Mod_r PF07200.13 KFX86276.1 - 0.1 12.7 8.8 0.16 12.1 8.8 1.2 1 0 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein Arm-DNA-bind_5 PF17293.2 KFX86276.1 - 0.16 12.4 4.1 4.7 7.7 0.9 3.0 2 1 1 3 3 3 0 Arm DNA-binding domain CCDC144C PF14915.6 KFX86276.1 - 0.23 10.6 10.7 0.33 10.0 10.7 1.2 1 0 0 1 1 1 0 CCDC144C protein coiled-coil region DUF4795 PF16043.5 KFX86276.1 - 0.25 10.9 5.6 0.45 10.1 5.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4795) Atg14 PF10186.9 KFX86276.1 - 0.26 10.3 4.0 0.39 9.8 4.0 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Spc7 PF08317.11 KFX86276.1 - 0.5 9.2 8.9 0.77 8.6 8.9 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF3584 PF12128.8 KFX86276.1 - 0.54 7.7 9.6 0.75 7.2 9.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) APG6_N PF17675.1 KFX86276.1 - 0.55 10.7 18.1 0.041 14.4 11.5 2.1 2 1 1 3 3 2 0 Apg6 coiled-coil region TPR_MLP1_2 PF07926.12 KFX86276.1 - 0.58 10.2 15.9 0.027 14.5 10.1 1.7 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein LPP PF04728.13 KFX86276.1 - 0.64 10.4 4.9 2.6 8.5 2.4 2.7 2 1 1 3 3 3 0 Lipoprotein leucine-zipper Macoilin PF09726.9 KFX86276.1 - 1.1 7.7 7.6 1.6 7.2 7.6 1.1 1 0 0 1 1 1 0 Macoilin family NYD-SP28_assoc PF14775.6 KFX86276.1 - 1.4 9.1 5.0 1.1 9.4 2.1 2.3 2 1 0 2 2 2 0 Sperm tail C-terminal domain Spc24 PF08286.11 KFX86276.1 - 1.8 8.8 6.4 8.4 6.7 2.0 2.2 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 GAS PF13851.6 KFX86276.1 - 1.9 7.8 13.2 0.66 9.3 9.6 1.8 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding ZapB PF06005.12 KFX86276.1 - 2.3 8.7 15.6 42 4.7 12.1 3.0 2 1 0 2 2 2 0 Cell division protein ZapB PRKG1_interact PF15898.5 KFX86276.1 - 3.4 8.6 14.3 2.8 8.9 12.1 1.8 2 0 0 2 2 2 0 cGMP-dependent protein kinase interacting domain DivIC PF04977.15 KFX86276.1 - 7.9 6.3 13.1 3.1 7.6 5.8 3.0 2 1 1 3 3 3 0 Septum formation initiator THOC7 PF05615.13 KFX86276.1 - 8.7 6.6 19.7 3.6 7.9 5.3 2.6 2 1 1 3 3 3 0 Tho complex subunit 7 Cupin_1 PF00190.22 KFX86278.1 - 1.1e-17 64.1 0.5 1.8e-17 63.4 0.5 1.3 1 0 0 1 1 1 1 Cupin tify PF06200.14 KFX86278.1 - 0.0081 15.5 0.2 0.017 14.4 0.2 1.5 1 0 0 1 1 1 1 tify domain Transglut_core3 PF13471.6 KFX86281.1 - 0.096 12.6 0.7 1.3 9.0 0.1 2.6 2 1 0 2 2 2 0 Transglutaminase-like superfamily Seryl_tRNA_N PF02403.22 KFX86281.1 - 0.22 11.8 12.8 0.076 13.2 6.3 2.4 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain TPR_MLP1_2 PF07926.12 KFX86281.1 - 2 8.5 9.5 5 7.2 1.1 3.0 1 1 2 3 3 3 0 TPR/MLP1/MLP2-like protein ZapB PF06005.12 KFX86281.1 - 3.4 8.2 10.4 1.2 9.7 1.7 3.3 2 1 0 2 2 2 0 Cell division protein ZapB Sec10 PF07393.11 KFX86287.1 - 7.3e-141 471.0 2.7 8.1e-141 470.8 2.7 1.0 1 0 0 1 1 1 1 Exocyst complex component Sec10 zf-RING_2 PF13639.6 KFX86297.1 - 5.4e-10 39.4 8.8 9.4e-10 38.7 8.8 1.4 1 0 0 1 1 1 1 Ring finger domain zf-ANAPC11 PF12861.7 KFX86297.1 - 5.1e-07 29.7 2.1 1e-06 28.7 2.1 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.7 KFX86297.1 - 7.9e-07 29.3 9.1 2e-06 27.9 9.1 1.7 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 KFX86297.1 - 1.5e-06 28.0 8.9 2.6e-06 27.2 8.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) FANCL_C PF11793.8 KFX86297.1 - 8e-06 25.9 8.0 2.5e-05 24.4 8.0 1.9 1 1 0 1 1 1 1 FANCL C-terminal domain Zn_ribbon_17 PF17120.5 KFX86297.1 - 4e-05 23.2 6.2 8.1e-05 22.2 6.2 1.4 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-RING_UBOX PF13445.6 KFX86297.1 - 0.00035 20.5 2.8 0.00035 20.5 2.8 1.8 1 1 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 KFX86297.1 - 0.00037 20.3 8.5 0.00079 19.2 8.5 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) RINGv PF12906.7 KFX86297.1 - 0.0016 18.5 7.2 0.0036 17.4 7.2 1.6 1 0 0 1 1 1 1 RING-variant domain zf-RING_11 PF17123.5 KFX86297.1 - 0.0028 17.4 4.5 0.0082 15.9 4.5 1.9 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4_3 PF13920.6 KFX86297.1 - 0.0029 17.4 5.1 0.0052 16.6 5.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KFX86297.1 - 0.0073 16.3 8.4 0.013 15.4 8.4 1.4 1 0 0 1 1 1 1 zinc-RING finger domain C1_1 PF00130.22 KFX86297.1 - 0.013 15.4 4.4 0.013 15.4 4.4 2.0 1 1 1 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Prok-RING_4 PF14447.6 KFX86297.1 - 0.014 15.3 7.9 0.039 13.8 8.0 1.8 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 zf-RING-like PF08746.11 KFX86297.1 - 0.041 14.2 7.3 0.097 13.0 7.3 1.7 1 0 0 1 1 1 0 RING-like domain zf-RING_4 PF14570.6 KFX86297.1 - 0.12 12.2 5.8 4.3 7.2 5.8 2.3 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING_6 PF14835.6 KFX86297.1 - 0.35 10.8 3.5 0.79 9.6 3.5 1.6 1 1 0 1 1 1 0 zf-RING of BARD1-type protein Zf_RING PF16744.5 KFX86297.1 - 0.5 10.5 2.7 1 9.5 2.7 1.5 1 0 0 1 1 1 0 KIAA1045 RING finger PHD PF00628.29 KFX86297.1 - 0.53 10.2 7.0 1.1 9.2 7.0 1.6 1 0 0 1 1 1 0 PHD-finger Prok-RING_1 PF14446.6 KFX86297.1 - 0.79 9.7 4.6 3.7 7.5 0.0 2.4 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 DUF4602 PF15375.6 KFX86299.1 - 2.5e-07 31.1 14.8 9.4e-06 26.0 14.8 3.0 1 1 0 1 1 1 1 Domain of unknown function (DUF4602) BUD22 PF09073.10 KFX86299.1 - 0.19 11.0 18.5 0.24 10.7 18.5 1.2 1 0 0 1 1 1 0 BUD22 PI3K_1B_p101 PF10486.9 KFX86299.1 - 2.8 5.6 8.3 3.8 5.2 8.3 1.2 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit Sugar_tr PF00083.24 KFX86301.1 - 3.4e-77 260.2 23.5 1e-76 258.7 23.5 1.6 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KFX86301.1 - 2.4e-26 92.5 44.4 1.7e-19 70.0 15.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 KFX86301.1 - 0.59 8.4 16.8 1.6 6.9 2.1 3.2 1 1 1 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family eIF-6 PF01912.18 KFX86303.1 - 4e-80 267.8 0.9 6.2e-80 267.2 0.9 1.3 1 0 0 1 1 1 1 eIF-6 family HupE_UreJ PF04955.12 KFX86303.1 - 0.042 13.3 0.1 0.075 12.5 0.1 1.4 1 0 0 1 1 1 0 HupE / UreJ protein LRIF1 PF15741.5 KFX86308.1 - 0.035 12.6 0.1 0.038 12.5 0.1 1.0 1 0 0 1 1 1 0 Ligand-dependent nuclear receptor-interacting factor 1 DUF4446 PF14584.6 KFX86309.1 - 0.25 11.3 0.7 0.49 10.4 0.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4446) EIIBC-GUT_N PF03612.14 KFX86309.1 - 1.3 8.7 4.2 3.1 7.5 4.2 1.5 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus DUF935 PF06074.12 KFX86309.1 - 4.6 5.9 12.4 4.6 5.9 5.8 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF935) MMR_HSR1 PF01926.23 KFX86310.1 - 7.4e-17 61.5 0.0 2.7e-16 59.7 0.0 2.0 1 1 1 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 KFX86310.1 - 0.00041 19.9 0.0 0.0011 18.5 0.0 1.7 2 0 0 2 2 2 1 Ferrous iron transport protein B AAA_21 PF13304.6 KFX86310.1 - 0.06 13.1 0.0 1.8 8.3 0.0 2.0 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 KFX86310.1 - 1.5 9.3 6.5 32 4.9 6.5 2.5 1 1 0 1 1 1 0 AAA domain SHMT PF00464.19 KFX86312.1 - 1.2e-127 425.9 0.0 1.4e-127 425.7 0.0 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Aminotran_1_2 PF00155.21 KFX86312.1 - 0.072 12.2 0.0 0.14 11.3 0.0 1.5 1 1 0 1 1 1 0 Aminotransferase class I and II RNA_POL_M_15KD PF02150.16 KFX86313.1 - 9.8e-08 31.8 0.4 1.4e-07 31.3 0.4 1.3 1 0 0 1 1 1 1 RNA polymerases M/15 Kd subunit Tnp_zf-ribbon_2 PF13842.6 KFX86313.1 - 0.056 14.3 1.2 0.073 13.9 0.6 1.4 1 1 1 2 2 2 0 DDE_Tnp_1-like zinc-ribbon GFA PF04828.14 KFX86313.1 - 0.058 13.7 0.1 0.058 13.7 0.1 1.1 1 0 0 1 1 1 0 Glutathione-dependent formaldehyde-activating enzyme DcuA_DcuB PF03605.14 KFX86316.1 - 0.33 9.8 0.1 0.43 9.4 0.1 1.1 1 0 0 1 1 1 0 Anaerobic c4-dicarboxylate membrane transporter U1snRNP70_N PF12220.8 KFX86316.1 - 6.8 7.4 8.0 1.1e+02 3.6 8.0 2.2 1 1 0 1 1 1 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal TPP_enzyme_C PF02775.21 KFX86318.1 - 6.7e-45 152.6 0.0 8e-45 152.4 0.0 1.1 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain RRM_1 PF00076.22 KFX86320.1 - 4.7e-39 132.1 0.3 1.1e-18 66.7 0.1 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM PF05172.13 KFX86320.1 - 0.066 13.2 0.1 0.21 11.6 0.0 1.8 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif RRM_7 PF16367.5 KFX86320.1 - 0.088 12.9 0.0 12 6.1 0.0 2.8 2 1 0 2 2 2 0 RNA recognition motif Croc_4 PF17691.1 KFX86321.1 - 0.036 14.1 2.5 0.057 13.5 2.5 1.3 1 0 0 1 1 1 0 Contingent replication of cDNA 4 Pex14_N PF04695.13 KFX86321.1 - 2.2 8.9 10.6 0.43 11.2 4.5 2.1 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF913 PF06025.12 KFX86321.1 - 3.4 6.5 6.7 11 4.9 0.2 2.0 2 0 0 2 2 2 0 Domain of Unknown Function (DUF913) Plasmodium_Vir PF05795.11 KFX86321.1 - 10 5.5 14.9 5.2 6.4 6.8 2.0 2 0 0 2 2 2 0 Plasmodium vivax Vir protein Molybdopterin PF00384.22 KFX86322.1 - 2.1e-28 99.4 0.0 2.9e-28 99.0 0.0 1.1 1 0 0 1 1 1 1 Molybdopterin oxidoreductase NADH_dhqG_C PF09326.11 KFX86322.1 - 4.1e-20 72.2 0.0 7.8e-20 71.3 0.0 1.5 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase subunit G, C-terminal PP-binding PF00550.25 KFX86324.1 - 1.7e-06 28.2 0.0 3.7e-06 27.2 0.0 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site AMP-binding PF00501.28 KFX86324.1 - 0.0014 17.3 0.0 0.0025 16.5 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KFX86324.1 - 0.081 13.9 0.1 0.22 12.5 0.0 1.8 2 0 0 2 2 2 0 AMP-binding enzyme C-terminal domain Ribosomal_L4 PF00573.22 KFX86326.1 - 1.1e-24 87.2 0.0 1.2e-24 87.0 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family DUF4049 PF13258.6 KFX86326.1 - 0.092 11.8 0.0 0.12 11.4 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4049) SET PF00856.28 KFX86328.1 - 0.071 13.5 1.5 0.083 13.3 1.5 1.2 1 0 0 1 1 1 0 SET domain Asp-B-Hydro_N PF05279.11 KFX86328.1 - 0.9 9.6 12.3 1.2 9.2 12.3 1.1 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region AIF-MLS PF14962.6 KFX86328.1 - 0.91 9.5 17.2 1.4 8.9 17.2 1.2 1 0 0 1 1 1 0 Mitochondria Localisation Sequence DAG_kinase_N PF14513.6 KFX86328.1 - 0.93 9.7 4.9 1.4 9.1 4.9 1.3 1 0 0 1 1 1 0 Diacylglycerol kinase N-terminus SAGA-Tad1 PF12767.7 KFX86328.1 - 1.9 8.2 8.5 2.2 7.9 8.5 1.2 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit CDC45 PF02724.14 KFX86328.1 - 2.1 6.5 9.7 2.2 6.5 9.7 1.0 1 0 0 1 1 1 0 CDC45-like protein DUF2151 PF10221.9 KFX86328.1 - 3.3 6.2 7.3 3.8 6.0 7.3 1.0 1 0 0 1 1 1 0 Cell cycle and development regulator EMC3_TMCO1 PF01956.16 KFX86328.1 - 3.4 7.4 5.4 4.8 6.9 5.4 1.3 1 0 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like Borrelia_P83 PF05262.11 KFX86328.1 - 5.2 5.5 21.4 6.6 5.1 21.4 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein V_ATPase_I PF01496.19 KFX86328.1 - 6.7 4.5 5.6 7.4 4.3 5.6 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Presenilin PF01080.17 KFX86328.1 - 7.2 5.3 12.6 8.2 5.1 12.6 1.1 1 0 0 1 1 1 0 Presenilin PA26 PF04636.13 KFX86328.1 - 7.6 5.3 6.7 9.3 5.0 6.7 1.0 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) Hid1 PF12722.7 KFX86328.1 - 8.4 4.4 8.2 9.3 4.2 8.2 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Abhydrolase_3 PF07859.13 KFX86330.1 - 6.8e-06 26.1 0.0 1.3e-05 25.2 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_3 PF07859.13 KFX86331.1 - 0.08 12.8 1.7 0.27 11.1 0.7 2.0 2 0 0 2 2 2 0 alpha/beta hydrolase fold DDE_1 PF03184.19 KFX86332.1 - 3.9e-29 101.5 0.2 3.9e-29 101.5 0.2 1.5 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.16 KFX86332.1 - 0.0016 18.4 1.1 0.0091 16.0 0.0 2.7 3 0 0 3 3 3 1 Tc5 transposase DNA-binding domain DDE_3 PF13358.6 KFX86332.1 - 0.002 17.9 0.1 0.017 14.8 0.0 2.4 3 0 0 3 3 3 1 DDE superfamily endonuclease Lipase_GDSL_2 PF13472.6 KFX86334.1 - 9.7e-18 65.2 0.4 1.5e-17 64.6 0.4 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 KFX86334.1 - 5.1e-09 36.4 0.1 1.3e-08 35.0 0.1 1.7 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase OSK PF17182.4 KFX86334.1 - 0.0088 15.3 0.0 0.012 14.8 0.0 1.1 1 0 0 1 1 1 1 OSK domain Abhydrolase_1 PF00561.20 KFX86335.1 - 2.7e-09 37.0 0.0 3.2e-09 36.8 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_4 PF08386.10 KFX86335.1 - 0.12 12.5 0.0 0.21 11.7 0.0 1.4 1 0 0 1 1 1 0 TAP-like protein Sec1 PF00995.23 KFX86337.1 - 7.2e-16 58.5 0.0 8.6e-16 58.3 0.0 1.0 1 0 0 1 1 1 1 Sec1 family 3HCDH_N PF02737.18 KFX86345.1 - 1.8e-32 112.7 0.0 2.6e-32 112.2 0.0 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.22 KFX86345.1 - 8.8e-10 39.1 0.0 1.9e-09 38.0 0.0 1.7 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain DUF1015 PF06245.11 KFX86345.1 - 0.13 11.1 0.0 0.19 10.6 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1015) SpoIIIAH PF12685.7 KFX86347.1 - 4.3 7.1 20.6 6.5 6.5 20.6 1.4 1 0 0 1 1 1 0 SpoIIIAH-like protein Zip PF02535.22 KFX86349.1 - 6.6e-44 150.5 0.3 7.9e-44 150.2 0.3 1.0 1 0 0 1 1 1 1 ZIP Zinc transporter DUF2486 PF10667.9 KFX86351.1 - 6.4 6.9 17.3 1.1 9.4 13.5 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF2486) Glyco_hydro_7 PF00840.20 KFX86352.1 - 1.9e-31 109.2 0.0 3.7e-31 108.3 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 7 Pec_lyase_C PF00544.19 KFX86352.1 - 3.4e-13 49.7 5.6 2.3e-11 43.7 5.6 2.4 1 1 0 1 1 1 1 Pectate lyase Beta_helix PF13229.6 KFX86352.1 - 2.6e-06 27.4 4.8 4.7e-06 26.5 4.8 1.4 1 0 0 1 1 1 1 Right handed beta helix region DHFR_1 PF00186.19 KFX86360.1 - 9.8e-30 103.4 0.0 7.2e-23 81.1 0.0 2.4 2 1 0 2 2 2 2 Dihydrofolate reductase RRM_1 PF00076.22 KFX86362.1 - 3.5e-21 74.8 0.0 4.3e-21 74.5 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KFX86362.1 - 0.0014 18.7 0.0 0.002 18.2 0.0 1.3 1 1 0 1 1 1 1 RNA recognition motif PAP_PilO PF06864.12 KFX86362.1 - 0.018 13.9 0.1 0.02 13.7 0.1 1.0 1 0 0 1 1 1 0 Pilin accessory protein (PilO) Isochorismatase PF00857.20 KFX86363.1 - 2.9e-08 34.1 0.0 5.1e-08 33.3 0.0 1.4 1 0 0 1 1 1 1 Isochorismatase family MFS_1 PF07690.16 KFX86365.1 - 8e-24 84.2 19.5 9.4e-24 84.0 19.5 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_1_like PF12832.7 KFX86365.1 - 0.23 10.3 9.1 0.012 14.5 1.4 2.1 1 1 1 2 2 2 0 MFS_1 like family Epimerase PF01370.21 KFX86367.1 - 1.8e-19 70.2 0.1 5.1e-19 68.7 0.1 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KFX86367.1 - 5.7e-17 62.1 0.0 3e-13 49.9 0.0 2.2 2 0 0 2 2 2 2 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 KFX86367.1 - 1.4e-10 40.8 0.0 1.2e-07 31.1 0.0 2.1 2 0 0 2 2 2 2 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.12 KFX86367.1 - 4.1e-07 29.4 0.0 6.6e-07 28.8 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein RmlD_sub_bind PF04321.17 KFX86367.1 - 2.1e-05 23.8 0.1 3.4e-05 23.1 0.1 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain 3Beta_HSD PF01073.19 KFX86367.1 - 4.8e-05 22.5 0.0 7.6e-05 21.8 0.0 1.4 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Acyl_transf_1 PF00698.21 KFX86370.1 - 9.3e-34 117.4 0.0 1.2e-33 117.0 0.0 1.0 1 0 0 1 1 1 1 Acyl transferase domain SAT PF16073.5 KFX86370.1 - 0.011 15.5 4.1 0.2 11.4 4.1 2.2 1 1 0 1 1 1 0 Starter unit:ACP transacylase in aflatoxin biosynthesis Pkinase PF00069.25 KFX86374.1 - 1.2e-66 224.8 0.0 1.6e-66 224.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFX86374.1 - 9.1e-31 107.1 0.0 1.2e-30 106.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KFX86374.1 - 5.1e-05 22.7 0.0 0.00014 21.3 0.0 1.6 1 1 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 KFX86374.1 - 0.00076 18.5 0.1 0.0011 18.1 0.1 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Pkinase_fungal PF17667.1 KFX86374.1 - 0.019 13.7 0.0 0.033 13.0 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase APH PF01636.23 KFX86374.1 - 0.15 12.0 0.1 0.46 10.4 0.1 1.7 1 1 1 2 2 2 0 Phosphotransferase enzyme family ADH_N_2 PF16884.5 KFX86377.1 - 0.063 13.2 0.0 0.072 13.0 0.0 1.1 1 0 0 1 1 1 0 N-terminal domain of oxidoreductase Chitin_synth_2 PF03142.15 KFX86379.1 - 4.7e-88 296.1 5.1 2.5e-87 293.7 5.8 1.7 2 0 0 2 2 2 1 Chitin synthase DEK_C PF08766.11 KFX86379.1 - 3.8e-16 58.7 0.0 4.1e-15 55.4 0.0 2.1 2 0 0 2 2 2 1 DEK C terminal domain Glyco_tranf_2_3 PF13641.6 KFX86379.1 - 0.044 13.7 0.2 0.081 12.8 0.2 1.5 1 0 0 1 1 1 0 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.6 KFX86379.1 - 0.91 9.4 8.0 2.3 8.1 8.0 1.7 1 1 0 1 1 1 0 Glycosyl transferase family group 2 PB1 PF00564.24 KFX86380.1 - 6.8e-09 35.5 0.0 1.1e-08 34.9 0.0 1.3 1 0 0 1 1 1 1 PB1 domain DUF5645 PF18713.1 KFX86380.1 - 0.15 12.4 0.0 0.24 11.7 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5645) GATA PF00320.27 KFX86388.1 - 3.1e-05 23.5 5.6 0.0083 15.7 2.3 2.6 2 0 0 2 2 2 2 GATA zinc finger Macoilin PF09726.9 KFX86390.1 - 0.31 9.6 1.9 0.35 9.4 1.9 1.0 1 0 0 1 1 1 0 Macoilin family cNMP_binding PF00027.29 KFX86392.1 - 8.8e-31 105.8 0.0 1.6e-18 66.6 0.0 2.4 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain vATP-synt_E PF01991.18 KFX86397.1 - 9.3e-16 57.8 12.6 1.1e-15 57.6 12.6 1.1 1 0 0 1 1 1 1 ATP synthase (E/31 kDa) subunit Folliculin PF11704.8 KFX86397.1 - 0.64 9.9 4.5 0.69 9.8 4.5 1.1 1 0 0 1 1 1 0 Vesicle coat protein involved in Golgi to plasma membrane transport LRR_6 PF13516.6 KFX86398.1 - 0.81 9.9 17.2 2.9 8.2 0.1 5.4 6 0 0 6 6 6 0 Leucine Rich repeat Ferlin_C PF16165.5 KFX86399.1 - 0.15 12.0 0.0 0.23 11.4 0.0 1.2 1 0 0 1 1 1 0 Ferlin C-terminus PS-DH PF14765.6 KFX86404.1 - 1.2e-17 64.1 0.0 1.8e-17 63.6 0.0 1.2 1 0 0 1 1 1 1 Polyketide synthase dehydratase Acyl_transf_1 PF00698.21 KFX86404.1 - 4.9e-05 23.0 0.0 0.00078 19.0 0.0 2.0 1 1 0 1 1 1 1 Acyl transferase domain Glyco_transf_4 PF13439.6 KFX86404.1 - 0.091 12.8 0.0 0.16 12.0 0.0 1.4 1 0 0 1 1 1 0 Glycosyltransferase Family 4 S1 PF00575.23 KFX86405.1 - 1e-28 99.5 4.6 7.8e-11 42.2 0.0 4.3 4 0 0 4 4 4 4 S1 RNA binding domain RNase_II_C_S1 PF18614.1 KFX86405.1 - 0.0056 16.6 0.3 4.3 7.3 0.0 3.1 3 0 0 3 3 3 2 RNase II-type exonuclease C-terminal S1 domain ProQ_C PF17516.2 KFX86405.1 - 0.016 14.6 1.8 0.22 11.0 0.1 3.3 4 0 0 4 4 4 0 ProQ C-terminal domain Wyosine_form PF08608.12 KFX86407.1 - 1.6e-24 86.0 0.0 2.9e-24 85.2 0.0 1.4 1 0 0 1 1 1 1 Wyosine base formation Radical_SAM PF04055.21 KFX86407.1 - 6.5e-10 39.6 0.0 9.5e-10 39.1 0.0 1.3 1 0 0 1 1 1 1 Radical SAM superfamily His_biosynth PF00977.21 KFX86408.1 - 8.1e-19 68.0 0.0 9.4e-19 67.8 0.0 1.0 1 0 0 1 1 1 1 Histidine biosynthesis protein CDC50 PF03381.15 KFX86411.1 - 4.6e-87 292.1 0.0 5.6e-87 291.8 0.0 1.0 1 0 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family Asp4 PF16996.5 KFX86411.1 - 0.056 13.2 0.3 0.094 12.5 0.3 1.3 1 0 0 1 1 1 0 Accessory secretory protein Sec Asp4 SelK_SelG PF10961.8 KFX86416.1 - 1.9 9.1 7.5 0.2 12.3 2.9 1.8 2 1 0 2 2 2 0 Selenoprotein SelK_SelG vATP-synt_E PF01991.18 KFX86417.1 - 1.1e-44 152.3 1.6 1.2e-44 152.1 1.6 1.0 1 0 0 1 1 1 1 ATP synthase (E/31 kDa) subunit SCAN PF02023.17 KFX86417.1 - 0.075 12.9 0.0 0.12 12.2 0.0 1.3 1 0 0 1 1 1 0 SCAN domain PCP_red PF08369.10 KFX86419.1 - 0.0098 16.1 0.0 0.016 15.4 0.0 1.4 1 0 0 1 1 1 1 Proto-chlorophyllide reductase 57 kD subunit DUF1488 PF07369.11 KFX86419.1 - 0.11 12.5 0.0 0.18 11.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1488) DAGAT PF03982.13 KFX86424.1 - 4.7e-88 294.9 0.0 5.9e-88 294.6 0.0 1.0 1 0 0 1 1 1 1 Diacylglycerol acyltransferase MGC-24 PF05283.11 KFX86426.1 - 0.00017 22.0 3.8 0.00025 21.5 3.8 1.2 1 0 0 1 1 1 1 Multi-glycosylated core protein 24 (MGC-24), sialomucin TMEM154 PF15102.6 KFX86426.1 - 0.0019 18.1 0.1 0.0033 17.3 0.1 1.4 1 0 0 1 1 1 1 TMEM154 protein family Mucin PF01456.17 KFX86426.1 - 0.0091 16.0 9.5 0.014 15.4 9.5 1.2 1 0 0 1 1 1 1 Mucin-like glycoprotein DUF1180 PF06679.12 KFX86426.1 - 0.027 14.9 2.9 0.037 14.4 2.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) SOG2 PF10428.9 KFX86426.1 - 0.029 13.6 2.7 0.034 13.4 2.7 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein SKG6 PF08693.10 KFX86426.1 - 0.029 13.8 1.5 0.062 12.7 1.5 1.6 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Syndecan PF01034.20 KFX86426.1 - 0.057 13.3 0.0 0.11 12.5 0.0 1.4 1 0 0 1 1 1 0 Syndecan domain DUF5305 PF17231.2 KFX86426.1 - 0.2 11.1 0.5 0.4 10.0 0.5 1.6 1 1 0 1 1 1 0 Family of unknown function (DUF5305) Plasmodium_Vir PF05795.11 KFX86426.1 - 0.25 10.7 0.4 0.32 10.4 0.4 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein DUF908 PF06012.12 KFX86426.1 - 0.43 9.9 5.3 0.63 9.4 5.3 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) DUF515 PF04415.12 KFX86426.1 - 0.61 8.4 2.9 0.9 7.9 2.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF515) DNA_pol_E_B PF04042.16 KFX86429.1 - 5e-05 22.7 0.0 5.5e-05 22.6 0.0 1.0 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B DUF4246 PF14033.6 KFX86432.1 - 2.4e-83 280.8 0.0 2.7e-83 280.6 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4246) TFIIB_C_1 PF18542.1 KFX86437.1 - 0.051 13.6 0.1 0.058 13.4 0.1 1.1 1 0 0 1 1 1 0 Transcription factor IIB C-terminal module 1 FAP PF07174.11 KFX86437.1 - 0.32 10.4 17.4 0.32 10.4 17.4 1.1 1 0 0 1 1 1 0 Fibronectin-attachment protein (FAP) HLH PF00010.26 KFX86439.1 - 7e-16 57.9 0.0 1.1e-15 57.3 0.0 1.3 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain GAS PF13851.6 KFX86439.1 - 0.0023 17.3 0.4 0.004 16.5 0.4 1.4 1 0 0 1 1 1 1 Growth-arrest specific micro-tubule binding Goodbye PF17109.5 KFX86439.1 - 0.025 15.0 0.7 0.34 11.4 0.7 2.0 2 0 0 2 2 2 0 fungal STAND N-terminal Goodbye domain Smac_DIABLO PF09057.10 KFX86439.1 - 0.032 13.6 4.6 0.047 13.0 4.6 1.2 1 0 0 1 1 1 0 Second Mitochondria-derived Activator of Caspases ZapB PF06005.12 KFX86439.1 - 0.29 11.6 2.7 0.79 10.2 0.8 2.1 2 0 0 2 2 2 0 Cell division protein ZapB Nucleoporin_N PF08801.11 KFX86440.1 - 2.5e-19 69.4 0.0 3.1e-19 69.0 0.0 1.1 1 0 0 1 1 1 1 Nup133 N terminal like cNMPbd_u2 PF16643.5 KFX86441.1 - 4.1e-41 141.1 17.4 5.2e-41 140.7 17.4 1.1 1 0 0 1 1 1 1 Unstructured region on cNMP-binding protein F-box PF00646.33 KFX86441.1 - 2.9e-06 27.0 1.3 0.00014 21.7 0.7 2.6 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.7 KFX86441.1 - 0.002 18.0 1.2 0.0059 16.5 0.1 2.4 3 0 0 3 3 3 1 F-box-like LRR_1 PF00560.33 KFX86441.1 - 0.33 11.7 2.6 42 5.3 0.1 3.5 3 0 0 3 3 3 0 Leucine Rich Repeat adh_short PF00106.25 KFX86443.1 - 3.5e-23 82.1 0.0 4.3e-23 81.8 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KFX86443.1 - 1.6e-18 67.1 0.0 2e-18 66.8 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KFX86443.1 - 2.9e-08 33.8 0.0 3.9e-08 33.4 0.0 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KFX86443.1 - 0.013 15.0 0.0 0.016 14.6 0.0 1.1 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KFX86443.1 - 0.036 13.5 0.1 0.045 13.1 0.1 1.1 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase Membr_traf_MHD PF10540.9 KFX86444.1 - 3.7e-20 72.6 0.7 4.8e-10 39.8 0.4 2.2 1 1 1 2 2 2 2 Munc13 (mammalian uncoordinated) homology domain DUF1367 PF07105.11 KFX86444.1 - 0.1 12.3 0.0 0.22 11.2 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1367) K_channel_TID PF07941.11 KFX86444.1 - 3.5 8.1 7.9 0.83 10.1 2.6 2.2 2 0 0 2 2 2 0 Potassium channel Kv1.4 tandem inactivation domain Lyase_1 PF00206.20 KFX86446.1 - 4.3e-35 121.6 0.0 6e-35 121.1 0.0 1.2 1 0 0 1 1 1 1 Lyase FumaraseC_C PF10415.9 KFX86446.1 - 1.2e-22 80.0 0.0 2.2e-22 79.2 0.0 1.4 1 0 0 1 1 1 1 Fumarase C C-terminus IglC PF11550.8 KFX86446.1 - 0.11 12.0 0.0 0.73 9.2 0.0 2.0 2 0 0 2 2 2 0 Intracellular growth locus C protein zf-CCCH PF00642.24 KFX86447.1 - 3e-07 30.2 2.5 3e-07 30.2 2.5 3.1 3 0 0 3 3 3 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) RRM_1 PF00076.22 KFX86447.1 - 0.0039 17.0 0.0 0.0062 16.3 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf_CCCH_4 PF18345.1 KFX86447.1 - 0.0058 16.7 3.3 0.0058 16.7 3.3 3.3 3 0 0 3 3 3 1 Zinc finger domain Torus PF16131.5 KFX86447.1 - 0.17 12.6 3.4 0.55 10.9 0.2 2.3 2 0 0 2 2 2 0 Torus domain SCRG1 PF15224.6 KFX86447.1 - 0.76 9.9 5.1 1.2 9.3 0.3 2.4 2 0 0 2 2 2 0 Scrapie-responsive protein 1 PHM7_ext PF12621.8 KFX86449.1 - 1.4e-13 50.8 0.0 1.6e-13 50.7 0.0 1.1 1 0 0 1 1 1 1 Extracellular tail, of 10TM putative phosphate transporter Period_C PF12114.8 KFX86458.1 - 3.5 7.2 9.0 3.6 7.1 9.0 1.0 1 0 0 1 1 1 0 Period protein 2/3C-terminal region V-SNARE_C PF12352.8 KFX86459.1 - 2.5e-15 56.5 5.0 7.4e-15 55.0 0.3 2.3 2 0 0 2 2 2 2 Snare region anchored in the vesicle membrane C-terminus DIOX_N PF14226.6 KFX86460.1 - 8.7e-06 26.5 0.0 0.00017 22.3 0.0 2.1 1 1 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal Thaumatin PF00314.17 KFX86463.1 - 1.2e-39 136.1 0.6 1.5e-39 135.9 0.6 1.1 1 0 0 1 1 1 1 Thaumatin family Glyco_hydro_64 PF16483.5 KFX86463.1 - 0.24 10.7 0.4 13 4.9 0.0 2.1 2 0 0 2 2 2 0 Beta-1,3-glucanase MFS_1 PF07690.16 KFX86472.1 - 6.2e-21 74.7 5.7 7.1e-21 74.5 5.7 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KFX86472.1 - 2.4e-08 33.3 3.1 3.3e-08 32.8 3.1 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1_like PF12832.7 KFX86472.1 - 2.5e-05 23.3 3.3 2.5e-05 23.3 3.3 1.6 1 1 1 2 2 2 1 MFS_1 like family MFS_2 PF13347.6 KFX86472.1 - 0.00025 19.7 2.5 0.001 17.7 1.7 1.9 1 1 1 2 2 2 1 MFS/sugar transport protein TRI12 PF06609.13 KFX86472.1 - 0.032 12.7 2.5 0.04 12.3 2.5 1.1 1 0 0 1 1 1 0 Fungal trichothecene efflux pump (TRI12) MFS_3 PF05977.13 KFX86472.1 - 0.14 10.5 2.2 0.82 8.0 0.5 2.0 2 0 0 2 2 2 0 Transmembrane secretion effector DUF2530 PF10745.9 KFX86472.1 - 0.45 10.8 6.3 0.19 12.0 0.7 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF2530) Trehalase PF01204.18 KFX86475.1 - 2.2e-80 270.9 0.1 2.5e-80 270.8 0.1 1.0 1 0 0 1 1 1 1 Trehalase GCP_C_terminal PF04130.13 KFX86476.1 - 8.9e-30 104.2 0.0 1.3e-29 103.7 0.0 1.1 1 0 0 1 1 1 1 Gamma tubulin complex component C-terminal Zn_clus PF00172.18 KFX86477.1 - 1.7e-05 24.8 7.7 2.6e-05 24.2 7.7 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain EspB PF05802.11 KFX86477.1 - 0.043 13.8 0.5 0.049 13.6 0.5 1.1 1 0 0 1 1 1 0 Enterobacterial EspB protein TAFII55_N PF04658.13 KFX86477.1 - 0.12 12.0 0.7 0.19 11.4 0.7 1.2 1 0 0 1 1 1 0 TAFII55 protein conserved region TMEM247 PF15444.6 KFX86477.1 - 0.23 11.5 0.2 0.29 11.2 0.2 1.2 1 0 0 1 1 1 0 Transmembrane protein 247 Tropomyosin_1 PF12718.7 KFX86478.1 - 0.001 19.2 2.5 0.0014 18.8 2.5 1.1 1 0 0 1 1 1 1 Tropomyosin like DUF4570 PF15134.6 KFX86478.1 - 0.035 14.1 0.6 0.055 13.5 0.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4570) DUF4726 PF15855.5 KFX86478.1 - 0.037 14.2 0.3 0.037 14.2 0.3 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4726) GAS PF13851.6 KFX86478.1 - 0.14 11.5 5.1 0.18 11.1 5.1 1.1 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding FlaC_arch PF05377.11 KFX86478.1 - 0.22 11.9 1.1 0.34 11.3 1.1 1.2 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) DivIC PF04977.15 KFX86478.1 - 0.25 11.2 3.9 0.34 10.7 3.9 1.2 1 0 0 1 1 1 0 Septum formation initiator RRM_1 PF00076.22 KFX86479.1 - 9.2e-17 60.6 0.0 3.6e-13 49.1 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KFX86479.1 - 0.088 12.7 0.0 0.2 11.6 0.0 1.6 1 0 0 1 1 1 0 Occluded RNA-recognition motif Ku PF02735.16 KFX86481.1 - 1.3e-26 93.6 0.0 1.6e-26 93.3 0.0 1.1 1 0 0 1 1 1 1 Ku70/Ku80 beta-barrel domain CCER1 PF15482.6 KFX86483.1 - 0.012 15.5 3.3 0.35 10.7 0.2 2.2 2 0 0 2 2 2 0 Coiled-coil domain-containing glutamate-rich protein family 1 Glycophorin_A PF01102.18 KFX86483.1 - 0.032 14.5 0.0 0.068 13.4 0.0 1.5 1 0 0 1 1 1 0 Glycophorin A Podoplanin PF05808.11 KFX86483.1 - 0.067 13.3 3.2 0.14 12.3 3.2 1.5 1 0 0 1 1 1 0 Podoplanin G_glu_transpept PF01019.21 KFX86484.1 - 3.2e-69 234.0 0.0 3.6e-69 233.9 0.0 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase Methyltransf_11 PF08241.12 KFX86485.1 - 1.1e-06 29.1 0.0 3.6e-06 27.5 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 KFX86485.1 - 0.0069 17.1 0.0 0.035 14.8 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Ligase_CoA PF00549.19 KFX86486.1 - 3.7e-12 46.3 0.0 5.3e-12 45.8 0.0 1.2 1 0 0 1 1 1 1 CoA-ligase Citrate_synt PF00285.21 KFX86486.1 - 2.7e-06 26.7 0.2 6.6e-05 22.1 0.2 2.5 1 1 0 1 1 1 1 Citrate synthase, C-terminal domain Sec63 PF02889.16 KFX86491.1 - 7.9e-59 198.9 0.0 1.1e-58 198.4 0.0 1.2 1 0 0 1 1 1 1 Sec63 Brl domain ABC_tran PF00005.27 KFX86500.1 - 1.6e-06 28.7 0.0 3.2e-06 27.7 0.0 1.5 2 0 0 2 2 2 1 ABC transporter AAA_21 PF13304.6 KFX86500.1 - 0.00016 21.6 0.0 0.00019 21.3 0.0 1.1 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 KFX86500.1 - 0.054 12.9 0.0 0.071 12.5 0.0 1.1 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain Oxysterol_BP PF01237.18 KFX86503.1 - 1.4e-19 70.2 0.1 7e-11 41.6 0.0 2.1 1 1 1 2 2 2 2 Oxysterol-binding protein Na_trans_assoc PF06512.13 KFX86506.1 - 0.61 10.3 7.0 0.11 12.8 3.8 1.4 2 0 0 2 2 2 0 Sodium ion transport-associated DUF530 PF04409.12 KFX86510.1 - 0.045 12.1 0.1 0.057 11.8 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF530) Zn_clus PF00172.18 KFX86511.1 - 6.4e-08 32.6 9.1 1.1e-07 31.9 9.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-RING_2 PF13639.6 KFX86515.1 - 5.9e-09 36.1 1.2 8e-09 35.7 1.2 1.2 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 KFX86515.1 - 3.4e-05 24.1 2.9 9.5e-05 22.6 2.9 1.7 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 KFX86515.1 - 0.0001 22.2 4.0 0.00016 21.6 4.0 1.3 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 KFX86515.1 - 0.00014 21.6 1.8 0.00024 20.9 1.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 KFX86515.1 - 0.00024 21.1 0.6 0.00035 20.6 0.6 1.2 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_11 PF17123.5 KFX86515.1 - 0.00063 19.4 0.9 0.001 18.8 0.9 1.3 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4_3 PF13920.6 KFX86515.1 - 0.01 15.7 0.1 0.021 14.7 0.1 1.5 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KFX86515.1 - 0.039 13.8 0.4 0.06 13.2 0.4 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KFX86515.1 - 0.047 13.5 0.4 1 9.3 0.0 2.1 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 Zn-C2H2_12 PF18112.1 KFX86515.1 - 0.099 13.1 0.1 0.099 13.1 0.1 1.8 2 0 0 2 2 2 0 Autophagy receptor zinc finger-C2H2 domain Rad50_zn_hook PF04423.14 KFX86515.1 - 0.31 10.9 1.8 0.4 10.6 0.1 2.1 3 0 0 3 3 3 0 Rad50 zinc hook motif DUF4614 PF15391.6 KFX86516.1 - 0.031 14.3 1.2 0.031 14.3 1.2 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4614) Pirin_C PF05726.13 KFX86519.1 - 5.7e-24 84.5 0.0 8.2e-24 84.0 0.0 1.2 1 0 0 1 1 1 1 Pirin C-terminal cupin domain NDK PF00334.19 KFX86521.1 - 1.3e-17 64.0 0.0 1.6e-17 63.8 0.0 1.1 1 0 0 1 1 1 1 Nucleoside diphosphate kinase Cpn60_TCP1 PF00118.24 KFX86523.1 - 2e-19 69.6 0.0 2.2e-19 69.5 0.0 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Pro_Al_protease PF02983.14 KFX86523.1 - 0.094 12.8 0.0 0.44 10.6 0.0 1.9 2 0 0 2 2 2 0 Alpha-lytic protease prodomain Sec7 PF01369.20 KFX86525.1 - 1.3e-26 93.4 0.1 1.8e-26 93.0 0.1 1.2 1 0 0 1 1 1 1 Sec7 domain SAC3_GANP PF03399.16 KFX86525.1 - 0.052 12.9 0.1 0.073 12.4 0.1 1.2 1 0 0 1 1 1 0 SAC3/GANP family AMP-binding PF00501.28 KFX86528.1 - 8.6e-21 74.0 0.0 1e-20 73.8 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme PTase_Orf2 PF11468.8 KFX86528.1 - 0.081 12.3 0.0 0.11 11.9 0.0 1.1 1 0 0 1 1 1 0 Aromatic prenyltransferase Orf2 Ank_2 PF12796.7 KFX86530.1 - 7.4e-28 97.0 0.0 6.7e-13 49.0 0.0 2.5 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KFX86530.1 - 1.2e-23 80.6 0.0 1.6e-05 24.9 0.0 4.3 4 0 0 4 4 4 4 Ankyrin repeat Ank PF00023.30 KFX86530.1 - 2.8e-20 71.8 0.0 0.00027 21.3 0.0 4.3 4 0 0 4 4 4 4 Ankyrin repeat Ank_4 PF13637.6 KFX86530.1 - 6.6e-20 71.2 0.0 1e-08 35.5 0.0 2.6 1 1 0 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 KFX86530.1 - 6e-13 48.7 0.0 0.00067 19.9 0.0 3.4 1 1 2 3 3 3 3 Ankyrin repeats (many copies) DUF498 PF04430.14 KFX86530.1 - 0.0098 16.0 0.0 0.49 10.5 0.0 2.6 3 0 0 3 3 3 1 Protein of unknown function (DUF498/DUF598) PEGA PF08308.11 KFX86530.1 - 0.093 12.6 0.0 3.3 7.7 0.0 2.4 1 1 1 2 2 2 0 PEGA domain VWA_3_C PF18571.1 KFX86530.1 - 1.5 8.7 5.0 15 5.5 0.1 3.6 4 0 0 4 4 4 0 von Willebrand factor type A C-terminal domain IPK PF03770.16 KFX86536.1 - 3.8e-39 134.6 0.0 4.4e-39 134.4 0.0 1.0 1 0 0 1 1 1 1 Inositol polyphosphate kinase CblD PF07434.11 KFX86536.1 - 0.24 10.3 0.1 0.33 9.9 0.1 1.1 1 0 0 1 1 1 0 CblD like pilus biogenesis initiator polyprenyl_synt PF00348.17 KFX86541.1 - 4.1e-40 137.4 0.0 4.6e-40 137.3 0.0 1.0 1 0 0 1 1 1 1 Polyprenyl synthetase Aldo_ket_red PF00248.21 KFX86545.1 - 1.2e-20 73.9 0.0 1.7e-20 73.4 0.0 1.2 1 1 0 1 1 1 1 Aldo/keto reductase family YL1 PF05764.13 KFX86547.1 - 2.4e-34 119.5 12.0 2.8e-34 119.3 12.0 1.0 1 0 0 1 1 1 1 YL1 nuclear protein RhoGAP PF00620.27 KFX86550.1 - 5.3e-39 133.5 0.0 7e-39 133.1 0.0 1.2 1 0 0 1 1 1 1 RhoGAP domain Shisa PF13908.6 KFX86551.1 - 2.2 8.5 6.0 2.7 8.2 6.0 1.1 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator FAP PF07174.11 KFX86551.1 - 9 5.6 25.8 9.8 5.5 25.8 1.0 1 0 0 1 1 1 0 Fibronectin-attachment protein (FAP) CH PF00307.31 KFX86558.1 - 0.046 13.9 0.0 0.078 13.2 0.0 1.4 1 0 0 1 1 1 0 Calponin homology (CH) domain TAFII28 PF04719.14 KFX86559.1 - 1e-27 96.1 0.6 1.9e-27 95.2 0.6 1.5 1 1 0 1 1 1 1 hTAFII28-like protein conserved region Endonuc_Holl PF10107.9 KFX86559.1 - 0.12 12.3 0.2 0.27 11.1 0.0 1.6 2 0 0 2 2 2 0 Endonuclease related to archaeal Holliday junction resolvase 2OG-FeII_Oxy PF03171.20 KFX86560.1 - 4.6e-13 49.5 0.0 8.2e-13 48.7 0.0 1.4 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Lycopene_cycl PF05834.12 KFX86562.1 - 0.02 14.0 0.0 0.026 13.6 0.0 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein Amino_oxidase PF01593.24 KFX86562.1 - 0.074 12.3 0.2 0.11 11.7 0.2 1.1 1 0 0 1 1 1 0 Flavin containing amine oxidoreductase NAD_binding_9 PF13454.6 KFX86562.1 - 0.13 12.2 0.1 0.26 11.2 0.0 1.5 1 1 0 1 1 1 0 FAD-NAD(P)-binding DUF2057 PF09829.9 KFX86566.1 - 3.5 7.7 5.3 5.3 7.2 0.0 2.1 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2057) Glyco_hydro_18 PF00704.28 KFX86568.1 - 0.12 12.1 0.0 0.14 11.9 0.0 1.1 1 0 0 1 1 1 0 Glycosyl hydrolases family 18 Cu-oxidase_2 PF07731.14 KFX86569.1 - 1.6e-16 60.3 0.2 3e-16 59.4 0.2 1.4 1 0 0 1 1 1 1 Multicopper oxidase BCS1_N PF08740.11 KFX86571.1 - 6.2e-24 85.0 0.0 7e-24 84.8 0.0 1.0 1 0 0 1 1 1 1 BCS1 N terminal Pkinase_Tyr PF07714.17 KFX86577.1 - 9e-10 38.3 0.0 1e-09 38.1 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KFX86577.1 - 9.5e-10 38.3 0.0 1.1e-09 38.0 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Ferric_reduct PF01794.19 KFX86580.1 - 6.8e-14 52.1 3.4 6.8e-14 52.1 3.4 1.3 1 1 0 1 1 1 1 Ferric reductase like transmembrane component Methyltransf_11 PF08241.12 KFX86581.1 - 9.2e-13 48.7 0.0 1.5e-12 48.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KFX86581.1 - 7.5e-07 29.8 0.0 1.4e-06 28.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KFX86581.1 - 0.00019 22.1 0.0 0.00036 21.2 0.0 1.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 KFX86581.1 - 0.0014 18.5 0.0 0.0025 17.7 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KFX86581.1 - 0.0055 16.5 0.0 0.0086 15.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain NNMT_PNMT_TEMT PF01234.17 KFX86581.1 - 0.045 12.9 0.0 0.061 12.5 0.0 1.2 1 0 0 1 1 1 0 NNMT/PNMT/TEMT family Ubie_methyltran PF01209.18 KFX86581.1 - 0.062 12.6 0.0 0.12 11.7 0.0 1.5 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family PAPA-1 PF04795.12 KFX86582.1 - 2.7e-13 50.5 0.0 3.2e-13 50.3 0.0 1.1 1 0 0 1 1 1 1 PAPA-1-like conserved region Homeobox_KN PF05920.11 KFX86584.1 - 9.9e-21 73.4 0.1 1.7e-20 72.6 0.1 1.4 1 0 0 1 1 1 1 Homeobox KN domain Homeodomain PF00046.29 KFX86584.1 - 2.4e-08 33.7 0.3 3.4e-08 33.2 0.3 1.2 1 0 0 1 1 1 1 Homeodomain Pyridoxal_deC PF00282.19 KFX86585.1 - 2.6e-13 49.4 0.0 3.2e-13 49.1 0.0 1.0 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain DUF1168 PF06658.12 KFX86586.1 - 0.078 12.8 0.1 0.15 11.9 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1168) Cofilin_ADF PF00241.20 KFX86588.1 - 3.1e-13 49.6 0.0 3.4e-13 49.4 0.0 1.0 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein P_C10 PF14974.6 KFX86590.1 - 0.073 13.2 0.0 0.12 12.5 0.0 1.3 1 0 0 1 1 1 0 Protein C10 Importin_rep_5 PF18816.1 KFX86591.1 - 1.2e-22 79.9 2.1 2.5e-22 78.9 2.1 1.5 1 0 0 1 1 1 1 Importin repeat zf-RING_2 PF13639.6 KFX86592.1 - 2.7e-12 46.8 7.0 4e-12 46.3 7.0 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 KFX86592.1 - 5e-09 35.8 6.7 7.7e-09 35.2 6.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 KFX86592.1 - 3.8e-08 32.9 1.2 6.4e-08 32.2 1.2 1.4 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4 PF00097.25 KFX86592.1 - 4e-08 33.0 4.6 6.1e-08 32.4 4.6 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KFX86592.1 - 7.9e-07 28.9 3.8 1.2e-06 28.4 3.8 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.7 KFX86592.1 - 1.1e-06 28.8 9.7 3.5e-06 27.2 9.7 1.8 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 KFX86592.1 - 3.3e-05 23.8 1.5 3.3e-05 23.8 1.5 2.2 2 0 0 2 2 2 1 RING-type zinc-finger zf-ANAPC11 PF12861.7 KFX86592.1 - 0.00053 20.0 3.4 0.0016 18.5 3.4 1.7 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_3 PF13920.6 KFX86592.1 - 0.0023 17.8 3.1 0.0037 17.1 3.1 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.6 KFX86592.1 - 0.013 15.3 6.0 0.025 14.4 6.0 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-C3HC4_4 PF15227.6 KFX86592.1 - 0.019 15.1 3.3 0.04 14.1 3.3 1.6 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING Zn_ribbon_17 PF17120.5 KFX86592.1 - 0.023 14.3 5.1 0.046 13.4 5.1 1.4 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type Prok-RING_4 PF14447.6 KFX86592.1 - 0.049 13.5 5.5 0.1 12.5 5.5 1.5 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 PHD PF00628.29 KFX86592.1 - 0.081 12.8 5.1 0.15 11.9 5.1 1.5 1 0 0 1 1 1 0 PHD-finger FANCL_C PF11793.8 KFX86592.1 - 0.16 12.1 5.3 0.6 10.3 5.2 2.0 1 1 0 1 1 1 0 FANCL C-terminal domain zf-UDP PF14569.6 KFX86592.1 - 0.32 11.1 2.2 0.87 9.7 2.2 1.8 1 1 0 1 1 1 0 Zinc-binding RING-finger RINGv PF12906.7 KFX86592.1 - 0.33 11.1 5.7 0.83 9.8 5.7 1.7 1 1 0 1 1 1 0 RING-variant domain Prok-RING_1 PF14446.6 KFX86592.1 - 1.9 8.5 7.5 0.25 11.3 1.4 2.1 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 EVE PF01878.18 KFX86595.1 - 2.1e-14 53.8 0.1 2.4e-14 53.6 0.1 1.1 1 0 0 1 1 1 1 EVE domain DivIC PF04977.15 KFX86605.1 - 0.00046 19.9 0.7 0.00046 19.9 0.7 2.7 2 2 1 3 3 3 1 Septum formation initiator LPP PF04728.13 KFX86605.1 - 0.0011 19.3 1.5 0.086 13.2 0.4 2.6 1 1 1 2 2 2 1 Lipoprotein leucine-zipper FAM76 PF16046.5 KFX86605.1 - 0.0085 15.5 4.3 0.011 15.1 4.3 1.1 1 0 0 1 1 1 1 FAM76 protein DUF1192 PF06698.11 KFX86605.1 - 0.011 15.8 2.3 1.1 9.3 0.5 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF1192) Seryl_tRNA_N PF02403.22 KFX86605.1 - 0.011 15.9 1.1 0.011 15.9 1.1 1.9 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain SKA1 PF07160.12 KFX86605.1 - 0.019 14.9 0.7 0.019 14.9 0.7 2.0 1 1 1 2 2 2 0 Spindle and kinetochore-associated protein 1 TMF_TATA_bd PF12325.8 KFX86605.1 - 0.019 15.2 0.4 0.019 15.2 0.4 2.1 2 1 0 2 2 2 0 TATA element modulatory factor 1 TATA binding DUF641 PF04859.12 KFX86605.1 - 0.021 15.1 0.2 0.021 15.1 0.2 1.9 2 1 0 2 2 2 0 Plant protein of unknown function (DUF641) ZapB PF06005.12 KFX86605.1 - 0.023 15.1 1.7 0.023 15.1 1.7 2.8 2 2 1 3 3 3 0 Cell division protein ZapB ATG16 PF08614.11 KFX86605.1 - 0.026 14.7 0.7 0.026 14.7 0.7 2.2 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) SKA2 PF16740.5 KFX86605.1 - 0.041 13.7 0.2 0.084 12.7 0.2 1.5 1 0 0 1 1 1 0 Spindle and kinetochore-associated protein 2 Cep57_MT_bd PF06657.13 KFX86605.1 - 0.057 13.9 2.0 0.2 12.1 0.1 2.5 2 2 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 DUF4549 PF15082.6 KFX86605.1 - 0.059 13.2 2.7 0.95 9.2 0.2 2.6 2 1 1 3 3 3 0 Domain of unknown function (DUF4549) Med4 PF10018.9 KFX86605.1 - 0.07 12.8 0.2 0.07 12.8 0.2 2.0 2 0 0 2 2 2 0 Vitamin-D-receptor interacting Mediator subunit 4 YabA PF06156.13 KFX86605.1 - 0.13 12.9 0.2 0.13 12.9 0.2 2.3 2 1 0 2 2 2 0 Initiation control protein YabA Atg14 PF10186.9 KFX86605.1 - 0.14 11.2 3.9 0.23 10.5 3.9 1.6 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 APG6_N PF17675.1 KFX86605.1 - 0.21 12.1 0.2 0.21 12.1 0.2 2.1 2 0 0 2 2 2 0 Apg6 coiled-coil region DUF4618 PF15397.6 KFX86605.1 - 0.22 10.9 4.0 0.26 10.7 0.3 2.4 2 1 1 3 3 3 0 Domain of unknown function (DUF4618) Cnn_1N PF07989.11 KFX86605.1 - 0.25 11.5 0.2 0.25 11.5 0.2 2.4 2 1 0 2 2 2 0 Centrosomin N-terminal motif 1 Baculo_PEP_C PF04513.12 KFX86605.1 - 0.27 11.3 6.6 0.052 13.6 2.8 1.6 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus AT_hook PF02178.19 KFX86605.1 - 0.35 10.9 0.3 0.35 10.9 0.3 2.0 2 0 0 2 2 1 0 AT hook motif UPF0242 PF06785.11 KFX86605.1 - 0.35 10.9 4.7 0.34 11.0 0.2 2.1 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Fib_alpha PF08702.10 KFX86605.1 - 0.36 11.0 6.2 1.2 9.3 1.2 2.3 2 1 0 2 2 2 0 Fibrinogen alpha/beta chain family Syntaxin_2 PF14523.6 KFX86605.1 - 0.41 11.0 6.1 0.16 12.4 2.1 2.0 2 0 0 2 2 2 0 Syntaxin-like protein DUF1664 PF07889.12 KFX86605.1 - 0.45 10.6 2.4 0.26 11.3 0.3 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) KASH_CCD PF14662.6 KFX86605.1 - 0.6 9.9 8.6 0.32 10.8 0.2 2.7 2 2 0 2 2 2 0 Coiled-coil region of CCDC155 or KASH BST2 PF16716.5 KFX86605.1 - 0.62 10.7 7.6 0.11 13.1 1.0 2.6 2 2 0 2 2 2 0 Bone marrow stromal antigen 2 TPR_MLP1_2 PF07926.12 KFX86605.1 - 0.71 9.9 9.5 0.17 11.9 0.8 2.4 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein DUF16 PF01519.16 KFX86605.1 - 1.2 9.7 5.6 4.6 7.8 5.5 2.0 1 1 0 1 1 1 0 Protein of unknown function DUF16 DUF4407 PF14362.6 KFX86605.1 - 1.5 8.1 9.7 5.4 6.3 9.7 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) CENP-H PF05837.12 KFX86605.1 - 1.8 9.0 6.7 0.55 10.7 0.8 2.1 2 0 0 2 2 2 0 Centromere protein H (CENP-H) Spc7 PF08317.11 KFX86605.1 - 2.2 7.1 8.5 0.05 12.5 0.8 1.8 2 0 0 2 2 2 0 Spc7 kinetochore protein DUF2203 PF09969.9 KFX86605.1 - 2.3 9.0 6.7 1.3 9.7 0.4 2.1 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) DUF5082 PF16888.5 KFX86605.1 - 3 8.1 10.8 0.27 11.5 2.5 2.5 2 2 0 2 2 2 0 Domain of unknown function (DUF5082) Retrotran_gag_2 PF14223.6 KFX86606.1 - 1.5e-05 24.7 0.0 2.1e-05 24.2 0.0 1.1 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type Pkinase PF00069.25 KFX86608.1 - 1.8e-42 145.5 0.0 2e-42 145.4 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFX86608.1 - 7.8e-27 94.2 0.0 1e-26 93.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KFX86608.1 - 5.2e-05 22.2 0.0 7e-05 21.8 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 KFX86608.1 - 0.00011 21.6 0.0 0.00016 21.1 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.11 KFX86608.1 - 0.028 13.5 0.0 0.037 13.1 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Haspin_kinase PF12330.8 KFX86608.1 - 0.062 12.2 0.0 0.087 11.8 0.0 1.1 1 0 0 1 1 1 0 Haspin like kinase domain DUF4928 PF16280.5 KFX86608.1 - 0.16 11.2 0.0 0.24 10.6 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4928) GH131_N PF18271.1 KFX86724.1 - 6.8e-22 78.4 0.3 9.4e-22 77.9 0.3 1.1 1 0 0 1 1 1 1 Glycoside hydrolase 131 catalytic N-terminal domain CBM_1 PF00734.18 KFX86724.1 - 1.8e-13 50.1 13.0 4.2e-13 49.0 13.0 1.7 1 0 0 1 1 1 1 Fungal cellulose binding domain Toxin_7 PF05980.12 KFX86724.1 - 0.2 11.9 2.7 0.35 11.2 2.7 1.4 1 0 0 1 1 1 0 Toxin 7 Glyco_transf_7C PF02709.14 KFX86735.1 - 0.15 11.7 0.0 0.28 10.9 0.0 1.4 1 0 0 1 1 1 0 N-terminal domain of galactosyltransferase ABC_tran PF00005.27 KFX86768.1 - 7.6e-13 49.2 0.0 8.4e-13 49.0 0.0 1.0 1 0 0 1 1 1 1 ABC transporter Secretin_N PF03958.17 KFX86783.1 - 0.05 14.0 0.7 0.079 13.4 0.2 1.6 2 0 0 2 2 2 0 Bacterial type II/III secretion system short domain DLIC PF05783.11 KFX86783.1 - 0.49 9.2 6.8 0.56 9.0 6.8 1.0 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) Pol_alpha_B_N PF08418.10 KFX86783.1 - 2.6 8.0 7.9 3 7.7 7.9 1.1 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal SPX PF03105.19 KFX86783.1 - 3.1 7.6 12.8 3.4 7.5 12.8 1.0 1 0 0 1 1 1 0 SPX domain TPPII_N PF12583.8 KFX86783.1 - 9.6 6.8 12.8 21 5.7 6.0 2.1 2 0 0 2 2 2 0 Tripeptidyl peptidase II N terminal Chitin_synth_1 PF01644.17 KFX86875.1 - 0.082 12.9 0.0 0.082 12.9 0.0 1.1 1 0 0 1 1 1 0 Chitin synthase p450 PF00067.22 KFX86931.1 - 2.1e-26 92.7 0.0 2.3e-26 92.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 tRNA-synt_2 PF00152.20 KFX87015.1 - 1.7e-15 56.9 0.1 1.9e-15 56.8 0.1 1.0 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) PDCD2_C PF04194.13 KFX87145.1 - 5.2e-27 95.0 0.0 5.7e-27 94.9 0.0 1.0 1 0 0 1 1 1 1 Programmed cell death protein 2, C-terminal putative domain DUF3113 PF11310.8 KFX87145.1 - 0.035 14.0 0.1 0.054 13.4 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3113) WD40 PF00400.32 KFX87164.1 - 3.2e-06 27.8 0.5 6.5e-05 23.6 0.0 2.9 3 1 0 3 3 3 1 WD domain, G-beta repeat TP1 PF02079.16 KFX87210.1 - 0.015 15.2 0.1 0.021 14.7 0.1 1.4 1 0 0 1 1 1 0 Nuclear transition protein 1 BNR_3 PF13859.6 KFX87219.1 - 0.18 11.1 0.0 0.19 11.0 0.0 1.1 1 0 0 1 1 1 0 BNR repeat-like domain DUF5421 PF17458.2 KFX87253.1 - 0.26 10.7 10.7 0.26 10.6 10.7 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5421) DUF89 PF01937.19 KFX87279.1 - 2.7e-38 131.9 0.0 3e-38 131.7 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function DUF89 zf-FPG_IleRS PF06827.14 KFX87309.1 - 0.00018 21.3 1.1 0.13 12.2 0.0 2.6 2 0 0 2 2 2 2 Zinc finger found in FPG and IleRS Pex14_N PF04695.13 KFX87309.1 - 0.047 14.4 0.0 0.079 13.6 0.0 1.4 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DAO PF01266.24 KFX87317.1 - 9.3e-52 176.7 2.1 1.7e-51 175.9 2.1 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KFX87317.1 - 7.5e-06 26.1 0.2 1.8e-05 24.8 0.2 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 KFX87317.1 - 0.00014 21.9 3.0 0.00022 21.3 0.2 2.6 3 0 0 3 3 3 1 FAD-NAD(P)-binding Thi4 PF01946.17 KFX87317.1 - 0.00024 20.4 0.0 0.00051 19.4 0.0 1.5 1 0 0 1 1 1 1 Thi4 family Pyr_redox_3 PF13738.6 KFX87317.1 - 0.00031 20.1 0.0 0.15 11.3 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KFX87317.1 - 0.00044 19.4 0.1 0.0058 15.7 0.1 2.2 2 0 0 2 2 2 1 Lycopene cyclase protein Pyr_redox_2 PF07992.14 KFX87317.1 - 0.00082 18.7 0.0 0.0013 18.0 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KFX87317.1 - 0.011 14.5 0.0 1.5 7.4 0.1 2.2 2 0 0 2 2 2 0 HI0933-like protein FAD_binding_2 PF00890.24 KFX87317.1 - 0.012 14.7 0.9 0.021 14.0 0.9 1.3 1 0 0 1 1 1 0 FAD binding domain K_oxygenase PF13434.6 KFX87317.1 - 0.085 12.0 1.1 0.098 11.8 0.0 1.6 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) FNIP_N PF14636.6 KFX87319.1 - 3e-35 122.5 4.4 4.6e-35 121.9 0.0 3.0 3 0 0 3 3 3 1 Folliculin-interacting protein N-terminus FNIP_M PF14637.6 KFX87319.1 - 0.14 12.2 0.1 1 9.4 0.0 2.2 2 1 1 3 3 3 0 Folliculin-interacting protein middle domain Pneumo_att_G PF05539.11 KFX87319.1 - 2.6 7.5 6.1 6.9 6.2 6.1 1.6 1 0 0 1 1 1 0 Pneumovirinae attachment membrane glycoprotein G IF-2B PF01008.17 KFX87320.1 - 2e-47 161.7 0.0 2.3e-47 161.5 0.0 1.0 1 0 0 1 1 1 1 Initiation factor 2 subunit family DeoRC PF00455.22 KFX87320.1 - 0.0035 17.3 0.0 4 7.4 0.0 2.5 2 0 0 2 2 2 2 DeoR C terminal sensor domain Rib_5-P_isom_A PF06026.14 KFX87320.1 - 0.011 15.4 0.2 0.2 11.3 0.1 2.1 1 1 1 2 2 2 0 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) Anoctamin PF04547.12 KFX87322.1 - 1.4e-114 383.4 8.1 1.8e-114 383.1 8.1 1.0 1 0 0 1 1 1 1 Calcium-activated chloride channel Aldedh PF00171.22 KFX87326.1 - 1.2e-106 357.0 0.1 1.5e-106 356.7 0.1 1.1 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Homeodomain PF00046.29 KFX87327.1 - 1.8e-13 50.1 1.5 4e-13 49.0 1.5 1.6 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 KFX87327.1 - 0.0045 16.9 0.1 0.011 15.6 0.1 1.7 1 0 0 1 1 1 1 Homeobox KN domain SLC12 PF03522.15 KFX87327.1 - 6.6 5.6 8.3 9.9 5.1 8.3 1.2 1 0 0 1 1 1 0 Solute carrier family 12 Glyco_tranf_2_3 PF13641.6 KFX87338.1 - 5.3e-27 95.2 0.1 1e-26 94.2 0.0 1.4 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 KFX87338.1 - 1.5e-07 31.4 0.0 3.7e-07 30.1 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 KFX87338.1 - 1.6e-06 27.7 0.2 8.8e-06 25.3 0.2 1.9 1 1 0 1 1 1 1 Glycosyl transferase family 21 DUF4607 PF15380.6 KFX87355.1 - 0.63 9.5 5.3 4 6.8 0.0 3.4 1 1 2 4 4 4 0 Domain of unknown function (DUF4607) GFRP PF06399.13 KFX87355.1 - 1 9.3 4.1 7.1 6.6 0.1 3.1 3 0 0 3 3 3 0 GTP cyclohydrolase I feedback regulatory protein (GFRP) WD40 PF00400.32 KFX87362.1 - 3.3e-29 100.5 28.5 6.9e-06 26.7 0.0 7.4 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFX87362.1 - 4.4e-12 46.1 0.1 1.1 9.6 0.0 6.2 2 1 4 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KFX87362.1 - 0.0026 17.7 0.0 1.8 8.4 0.0 3.0 1 1 1 3 3 3 3 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 KFX87362.1 - 0.057 12.4 0.2 4.7 6.1 0.0 3.2 1 1 1 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein MBOAT PF03062.19 KFX87363.1 - 4.5e-21 75.6 13.9 6.6e-21 75.0 13.9 1.3 1 0 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family MBOAT_2 PF13813.6 KFX87363.1 - 0.004 17.4 1.2 0.011 15.9 1.2 1.7 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family Pox_I5 PF04713.12 KFX87363.1 - 0.03 14.3 1.5 0.07 13.2 0.2 2.2 2 0 0 2 2 2 0 Poxvirus protein I5 ICMT PF04140.14 KFX87364.1 - 9e-26 90.1 0.0 1.7e-25 89.3 0.0 1.4 1 0 0 1 1 1 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.13 KFX87364.1 - 1e-11 45.2 1.1 1e-11 45.2 1.1 1.8 2 0 0 2 2 2 1 Phospholipid methyltransferase DUF1295 PF06966.12 KFX87364.1 - 0.00053 19.6 0.2 0.00081 19.0 0.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) NnrU PF07298.11 KFX87364.1 - 0.00076 19.1 3.3 0.0015 18.0 3.3 1.6 1 1 0 1 1 1 1 NnrU protein RPAP1_N PF08621.10 KFX87374.1 - 0.068 13.0 0.0 0.11 12.3 0.0 1.3 1 0 0 1 1 1 0 RPAP1-like, N-terminal SH3_1 PF00018.28 KFX87376.1 - 2e-11 43.3 0.1 3.1e-11 42.7 0.1 1.3 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KFX87376.1 - 6.6e-09 35.5 0.0 9.8e-09 34.9 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 KFX87376.1 - 3.1e-06 26.8 0.0 5.2e-06 26.1 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain Pex14_N PF04695.13 KFX87376.1 - 0.0045 17.7 13.9 0.026 15.2 5.0 2.1 2 0 0 2 2 2 2 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF910 PF06014.11 KFX87376.1 - 0.057 13.4 0.0 0.11 12.5 0.0 1.5 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF910) DUF2076 PF09849.9 KFX87376.1 - 0.49 10.4 13.4 0.67 9.9 4.1 2.1 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2076) DUF202 PF02656.15 KFX87377.1 - 2.1e-22 79.3 1.3 2.1e-22 79.3 1.3 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF202) PLU-1 PF08429.11 KFX87388.1 - 2.7e-110 368.7 14.1 3.9e-107 358.3 12.7 2.2 2 0 0 2 2 2 2 PLU-1-like protein JmjC PF02373.22 KFX87388.1 - 1.3e-43 148.1 0.2 2.9e-43 146.9 0.2 1.7 1 0 0 1 1 1 1 JmjC domain, hydroxylase ARID PF01388.21 KFX87388.1 - 1.5e-22 80.0 0.0 4.9e-22 78.4 0.0 2.0 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain PHD PF00628.29 KFX87388.1 - 3.6e-17 62.0 32.3 7.4e-09 35.4 7.0 3.6 3 0 0 3 3 3 3 PHD-finger zf-C5HC2 PF02928.16 KFX87388.1 - 1.1e-11 44.9 6.6 3.1e-11 43.5 6.6 1.8 1 0 0 1 1 1 1 C5HC2 zinc finger JmjN PF02375.17 KFX87388.1 - 4.2e-11 42.6 2.4 1e-10 41.4 2.4 1.7 1 0 0 1 1 1 1 jmjN domain zf-PHD-like PF15446.6 KFX87388.1 - 0.27 10.8 10.3 1.2 8.7 2.4 2.8 2 0 0 2 2 2 0 PHD/FYVE-zinc-finger like domain zf-HC5HC2H_2 PF13832.6 KFX87388.1 - 6.3 7.0 16.6 0.28 11.4 1.6 3.4 3 0 0 3 3 3 0 PHD-zinc-finger like domain C1_1 PF00130.22 KFX87388.1 - 7.8 6.5 18.5 0.75 9.7 4.5 3.3 3 0 0 3 3 3 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Zf_RING PF16744.5 KFX87388.1 - 9.6 6.4 18.7 4.7 7.4 5.7 3.7 3 1 0 3 3 3 0 KIAA1045 RING finger DnaJ PF00226.31 KFX87391.1 - 8e-15 54.7 0.3 1.3e-14 54.1 0.3 1.3 1 0 0 1 1 1 1 DnaJ domain Mem_trans PF03547.18 KFX87394.1 - 5.1e-50 170.0 3.6 1.7e-49 168.3 3.6 1.7 1 1 0 1 1 1 1 Membrane transport protein ELFV_dehydrog PF00208.21 KFX87395.1 - 3.8e-62 210.2 0.0 6.2e-62 209.5 0.0 1.4 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Bac_GDH PF05088.12 KFX87395.1 - 4.6e-18 64.2 0.0 1.9e-14 52.3 0.0 2.2 2 0 0 2 2 2 2 Bacterial NAD-glutamate dehydrogenase ELFV_dehydrog_N PF02812.18 KFX87395.1 - 0.0082 16.0 0.0 0.041 13.8 0.0 2.1 2 0 0 2 2 2 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain HLH PF00010.26 KFX87396.1 - 1.1e-11 44.5 0.1 4.5e-11 42.5 0.1 2.0 1 1 0 1 1 1 1 Helix-loop-helix DNA-binding domain Zn_clus PF00172.18 KFX87428.1 - 0.0028 17.8 8.9 0.0064 16.6 8.9 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Bul1_C PF04426.12 KFX87428.1 - 0.1 12.0 0.1 0.29 10.5 0.1 1.7 1 0 0 1 1 1 0 Bul1 C terminus RSN1_7TM PF02714.15 KFX87429.1 - 2.3e-40 138.6 8.5 2.3e-40 138.6 8.5 1.6 2 0 0 2 2 2 1 Calcium-dependent channel, 7TM region, putative phosphate PHM7_ext PF12621.8 KFX87429.1 - 7.8e-16 58.0 0.0 1.3e-15 57.3 0.0 1.4 1 0 0 1 1 1 1 Extracellular tail, of 10TM putative phosphate transporter DUF2244 PF10003.9 KFX87429.1 - 0.091 12.4 0.4 0.091 12.4 0.4 2.1 2 0 0 2 2 2 0 Integral membrane protein (DUF2244) Zn_clus PF00172.18 KFX87438.1 - 6.2e-07 29.4 13.6 9.7e-07 28.8 13.6 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RskA PF10099.9 KFX87438.1 - 0.026 14.8 0.2 0.026 14.8 0.2 2.5 2 0 0 2 2 2 0 Anti-sigma-K factor rskA BAF1_ABF1 PF04684.13 KFX87438.1 - 0.61 9.1 3.4 2.9 6.9 0.1 2.0 2 0 0 2 2 2 0 BAF1 / ABF1 chromatin reorganising factor Cation_ATPase_C PF00689.21 KFX87447.1 - 3.8e-33 114.7 5.9 3.8e-33 114.7 5.9 2.2 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus PP2C PF00481.21 KFX87447.1 - 8.8e-32 110.7 0.0 1.3e-26 93.8 0.0 2.2 2 0 0 2 2 2 2 Protein phosphatase 2C E1-E2_ATPase PF00122.20 KFX87447.1 - 4.8e-19 68.6 0.9 1e-18 67.5 0.9 1.5 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase PF13246.6 KFX87447.1 - 5e-14 52.1 0.0 9.1e-14 51.3 0.0 1.4 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 KFX87447.1 - 1.1e-12 48.7 0.1 2e-08 34.8 0.0 3.3 3 1 0 3 3 3 2 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 KFX87447.1 - 0.00095 19.0 0.1 0.0018 18.1 0.1 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase DUF2231 PF09990.9 KFX87447.1 - 0.095 13.1 0.5 0.28 11.6 0.5 1.8 1 0 0 1 1 1 0 Predicted membrane protein (DUF2231) zf-C2H2 PF00096.26 KFX87452.1 - 4.8e-07 29.9 9.8 0.0019 18.6 3.8 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFX87452.1 - 4.6e-06 27.0 9.2 0.0079 17.0 2.8 2.9 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KFX87452.1 - 0.0003 21.1 3.3 0.0003 21.1 3.3 3.8 3 1 0 3 3 3 1 Zinc-finger double domain zf-C2H2_jaz PF12171.8 KFX87452.1 - 0.25 11.7 4.2 3.6 8.0 0.3 3.2 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-C2H2_3rep PF18868.1 KFX87452.1 - 0.27 11.9 6.5 0.63 10.7 0.8 2.5 2 1 1 3 3 3 0 Zinc finger C2H2-type, 3 repeats DUF3710 PF12502.8 KFX87459.1 - 0.07 12.8 0.0 0.13 11.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3710) Methyltransf_16 PF10294.9 KFX87459.1 - 0.16 11.7 0.0 4.7 6.9 0.0 2.1 2 0 0 2 2 2 0 Lysine methyltransferase RNA_pol_Rbc25 PF08292.12 KFX87460.1 - 2.5e-28 98.9 0.0 3.8e-28 98.3 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase III subunit Rpc25 SHS2_Rpb7-N PF03876.17 KFX87460.1 - 1.3e-15 57.5 0.0 2e-15 56.9 0.0 1.3 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 NUFIP1 PF10453.9 KFX87461.1 - 6.8e-08 32.2 0.9 6.8e-08 32.2 0.9 2.3 3 0 0 3 3 3 1 Nuclear fragile X mental retardation-interacting protein 1 (NUFIP1) zf_CCCH_4 PF18345.1 KFX87461.1 - 0.046 13.8 6.7 0.081 13.0 6.7 1.4 1 0 0 1 1 1 0 Zinc finger domain zf-CCCH PF00642.24 KFX87461.1 - 0.24 11.4 6.4 0.41 10.6 6.4 1.4 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) DUF2570 PF10828.8 KFX87461.1 - 4.9 7.0 5.5 11 5.8 5.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2570) Mitofilin PF09731.9 KFX87461.1 - 5.3 5.7 27.1 15 4.3 26.2 1.9 2 0 0 2 2 2 0 Mitochondrial inner membrane protein Glyco_hydro_17 PF00332.18 KFX87467.1 - 2.6e-08 33.8 2.2 0.00024 20.8 0.4 2.2 1 1 1 2 2 2 2 Glycosyl hydrolases family 17 DUF5326 PF17260.2 KFX87467.1 - 0.56 10.4 1.7 0.98 9.6 1.7 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5326) ETRAMP PF09716.10 KFX87467.1 - 9.5 6.4 9.5 0.14 12.3 0.3 2.2 2 0 0 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) GPW_gp25 PF04965.14 KFX87470.1 - 0.014 15.1 0.7 4.7 7.0 0.0 2.9 3 0 0 3 3 3 0 Gene 25-like lysozyme Mucin-like PF16058.5 KFX87470.1 - 0.67 10.1 6.6 0.18 11.9 0.8 2.1 1 1 1 2 2 2 0 Mucin-like Sugar_tr PF00083.24 KFX87472.1 - 6.3e-78 262.6 18.3 7.3e-78 262.4 18.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KFX87472.1 - 1.1e-33 116.6 49.2 3.7e-31 108.3 26.3 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 KFX87472.1 - 6.5e-06 24.8 0.9 6.5e-06 24.8 0.9 2.1 2 0 0 2 2 2 2 Fungal trichothecene efflux pump (TRI12) DUF554 PF04474.12 KFX87472.1 - 0.0017 17.9 1.2 0.0068 15.9 0.3 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF554) MFS_1 PF07690.16 KFX87473.1 - 8.4e-32 110.4 63.8 2.4e-30 105.7 53.2 2.5 1 1 1 2 2 2 2 Major Facilitator Superfamily Epimerase PF01370.21 KFX87474.1 - 5.6e-15 55.5 0.3 2.1e-14 53.6 0.3 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KFX87474.1 - 2.3e-10 39.9 0.0 3.2e-10 39.5 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 KFX87474.1 - 2.2e-08 33.9 0.0 3.6e-08 33.2 0.0 1.3 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.6 KFX87474.1 - 2.1e-06 27.8 0.1 9.5e-06 25.6 0.1 2.0 2 0 0 2 2 2 1 NAD(P)H-binding adh_short PF00106.25 KFX87474.1 - 4.9e-05 22.9 0.1 0.0017 17.8 0.0 2.2 2 0 0 2 2 2 1 short chain dehydrogenase NmrA PF05368.13 KFX87474.1 - 0.00017 21.2 0.0 0.00031 20.4 0.0 1.5 1 0 0 1 1 1 1 NmrA-like family NAD_binding_4 PF07993.12 KFX87474.1 - 0.001 18.3 0.1 0.0041 16.3 0.1 1.9 1 1 0 1 1 1 1 Male sterility protein KR PF08659.10 KFX87474.1 - 0.0015 18.5 0.4 0.01 15.8 0.4 2.0 1 1 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 KFX87474.1 - 0.0073 15.5 0.0 0.0098 15.1 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 KFX87474.1 - 0.1 11.7 0.1 0.62 9.1 0.0 2.0 2 0 0 2 2 2 0 RmlD substrate binding domain Fungal_trans PF04082.18 KFX87475.1 - 1.3e-10 40.8 0.0 2.5e-10 39.9 0.0 1.5 1 1 0 1 1 1 1 Fungal specific transcription factor domain Glyco_hydro_61 PF03443.14 KFX87476.1 - 3.3e-47 161.1 0.0 3.8e-47 160.9 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 MspA PF09203.11 KFX87476.1 - 0.016 15.1 0.1 0.031 14.1 0.0 1.5 1 1 0 1 1 1 0 MspA Glyco_hydro_61 PF03443.14 KFX87477.1 - 3e-55 187.4 0.3 3.6e-55 187.1 0.3 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Epimerase PF01370.21 KFX87478.1 - 5.4e-12 45.7 0.1 1.8e-10 40.7 0.1 2.1 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 KFX87478.1 - 1.3e-09 38.2 0.7 2e-09 37.6 0.7 1.3 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 KFX87478.1 - 4.3e-08 33.0 0.8 7.4e-08 32.2 0.8 1.4 1 0 0 1 1 1 1 NmrA-like family Semialdhyde_dh PF01118.24 KFX87478.1 - 0.00019 21.8 0.1 0.00042 20.7 0.1 1.6 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain 3Beta_HSD PF01073.19 KFX87478.1 - 0.0005 19.2 0.1 0.14 11.2 0.1 2.1 2 0 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 KFX87478.1 - 0.0053 16.0 0.0 0.019 14.2 0.0 1.9 2 0 0 2 2 2 1 Male sterility protein Polysacc_synt_2 PF02719.15 KFX87478.1 - 0.016 14.4 0.1 0.05 12.7 0.1 1.7 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein GDP_Man_Dehyd PF16363.5 KFX87478.1 - 0.049 13.0 0.0 0.25 10.7 0.0 2.0 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase TrkA_N PF02254.18 KFX87478.1 - 0.074 13.3 0.3 0.29 11.4 0.1 2.1 2 0 0 2 2 2 0 TrkA-N domain CLCA PF08434.11 KFX87478.1 - 0.14 11.5 0.1 2.4 7.4 0.0 2.1 2 0 0 2 2 2 0 Calcium-activated chloride channel N terminal ANXA2R PF15721.5 KFX87479.1 - 0.94 10.0 8.3 1.7 9.1 5.2 2.2 2 0 0 2 2 2 0 Annexin-2 receptor GCV_T PF01571.21 KFX87480.1 - 0.00014 21.3 0.0 0.00025 20.5 0.0 1.4 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain Bax1-I PF01027.20 KFX87496.1 - 2.5e-35 122.2 12.6 2.5e-35 122.2 12.6 1.4 2 0 0 2 2 2 1 Inhibitor of apoptosis-promoting Bax1 zf-C2H2 PF00096.26 KFX87498.1 - 0.17 12.4 0.2 0.39 11.3 0.2 1.7 1 0 0 1 1 1 0 Zinc finger, C2H2 type DnaJ PF00226.31 KFX87501.1 - 3.2e-21 75.2 2.8 4e-21 74.9 0.2 2.5 2 0 0 2 2 2 1 DnaJ domain Imm49 PF15575.6 KFX87501.1 - 0.028 14.2 0.1 0.043 13.6 0.1 1.3 1 0 0 1 1 1 0 Immunity protein 49 UPF0223 PF05256.12 KFX87501.1 - 0.3 11.5 3.5 0.83 10.0 3.1 2.1 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0223) PBECR1 PF18809.1 KFX87501.1 - 1.1 10.0 6.4 0.24 12.1 0.4 2.7 2 1 0 3 3 3 0 phage-Barnase-EndoU-ColicinE5/D-RelE like nuclease1 zf-C2H2 PF00096.26 KFX87503.1 - 2.9e-08 33.7 7.4 0.00065 20.0 0.5 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFX87503.1 - 0.00039 21.0 6.8 0.19 12.7 0.4 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger FOXP-CC PF16159.5 KFX87503.1 - 0.0059 17.2 0.8 0.017 15.8 0.4 2.0 1 1 0 1 1 1 1 FOXP coiled-coil domain MbtH PF03621.13 KFX87503.1 - 0.067 12.7 0.3 0.14 11.6 0.3 1.5 1 0 0 1 1 1 0 MbtH-like protein zf-H2C2_2 PF13465.6 KFX87503.1 - 8.4 7.0 7.5 31 5.2 1.7 3.2 3 0 0 3 3 3 0 Zinc-finger double domain Iso_dh PF00180.20 KFX87512.1 - 2e-102 342.9 0.0 2.4e-102 342.6 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Phage_30_3 PF08010.11 KFX87512.1 - 0.012 15.4 0.0 0.023 14.5 0.0 1.4 1 0 0 1 1 1 0 Bacteriophage protein GP30.3 HHH_2 PF12826.7 KFX87512.1 - 0.019 15.1 0.0 0.073 13.2 0.0 1.9 2 0 0 2 2 2 0 Helix-hairpin-helix motif E1-E2_ATPase PF00122.20 KFX87517.1 - 6.7e-34 117.0 0.0 6.7e-34 117.0 0.0 3.2 4 1 0 4 4 4 1 E1-E2 ATPase Hydrolase PF00702.26 KFX87517.1 - 1.7e-17 64.4 0.2 7.1e-17 62.4 0.1 2.1 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 KFX87517.1 - 4.5e-10 39.1 0.0 1.3e-09 37.6 0.0 1.8 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 KFX87517.1 - 0.0027 17.5 0.0 0.0068 16.2 0.0 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 KFX87517.1 - 0.005 16.9 0.0 0.011 15.8 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) PHO4 PF01384.20 KFX87517.1 - 0.31 10.0 13.8 0.027 13.5 0.9 3.1 2 1 0 2 2 2 0 Phosphate transporter family FA_desaturase PF00487.24 KFX87518.1 - 3.9e-06 26.9 1.2 4.8e-06 26.6 1.2 1.1 1 0 0 1 1 1 1 Fatty acid desaturase IPT PF01745.16 KFX87518.1 - 0.22 10.9 0.0 0.28 10.5 0.0 1.2 1 0 0 1 1 1 0 Isopentenyl transferase SUN PF03856.13 KFX87519.1 - 3.9e-88 295.0 11.7 5e-88 294.7 11.7 1.1 1 0 0 1 1 1 1 Beta-glucosidase (SUN family) CAP_N PF01213.19 KFX87519.1 - 0.49 9.8 3.2 0.76 9.2 3.2 1.3 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal CAP_GLY PF01302.25 KFX87525.1 - 4.1e-15 55.5 0.3 1e-14 54.3 0.3 1.7 1 0 0 1 1 1 1 CAP-Gly domain CLIP1_ZNF PF16641.5 KFX87525.1 - 1.5e-05 24.8 10.1 0.004 17.0 1.2 2.5 2 0 0 2 2 2 2 CLIP1 zinc knuckle Med4 PF10018.9 KFX87525.1 - 0.0019 17.9 2.2 0.0019 17.9 2.2 3.5 3 1 0 3 3 2 2 Vitamin-D-receptor interacting Mediator subunit 4 AAA_13 PF13166.6 KFX87525.1 - 0.0031 16.2 8.3 0.0031 16.2 8.3 2.9 2 1 0 3 3 3 1 AAA domain DivIC PF04977.15 KFX87525.1 - 0.017 14.8 2.0 0.017 14.8 2.0 4.5 3 1 1 5 5 5 0 Septum formation initiator NPV_P10 PF05531.12 KFX87525.1 - 0.025 15.0 4.0 5.8 7.5 0.4 3.2 3 0 0 3 3 3 0 Nucleopolyhedrovirus P10 protein Glutaredoxin2_C PF04399.13 KFX87525.1 - 0.14 12.0 3.3 7.4 6.4 0.3 2.8 2 1 0 2 2 2 0 Glutaredoxin 2, C terminal domain zf_PR_Knuckle PF18445.1 KFX87525.1 - 0.16 11.8 1.4 3.1 7.7 0.0 2.6 2 0 0 2 2 2 0 PR zinc knuckle motif DUF1664 PF07889.12 KFX87525.1 - 0.17 12.0 14.5 1.5 8.9 3.1 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) Fib_alpha PF08702.10 KFX87525.1 - 0.56 10.4 18.7 0.72 10.0 3.4 3.5 1 1 3 4 4 4 0 Fibrinogen alpha/beta chain family Pkip-1 PF06878.11 KFX87525.1 - 2.3 8.3 8.4 2.8 8.0 1.1 2.3 1 1 1 2 2 2 0 Pkip-1 protein BLOC1_2 PF10046.9 KFX87525.1 - 4.5 7.6 16.9 1.8 8.9 2.3 3.8 4 0 0 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 TPR_MLP1_2 PF07926.12 KFX87525.1 - 5.3 7.1 41.4 2.4 8.2 13.3 4.2 3 1 0 3 3 3 0 TPR/MLP1/MLP2-like protein Tup_N PF08581.10 KFX87525.1 - 5.9 7.3 22.2 1.3 9.4 1.5 4.4 3 2 1 4 4 4 0 Tup N-terminal Fez1 PF06818.15 KFX87525.1 - 9.1 6.7 42.9 0.48 10.8 14.2 3.3 1 1 3 4 4 4 0 Fez1 zf-TRAF PF02176.18 KFX87529.1 - 2e-09 38.0 17.9 0.00012 22.7 1.6 3.7 2 1 2 4 4 3 2 TRAF-type zinc finger zf-C3HC4_2 PF13923.6 KFX87529.1 - 1.3e-08 34.6 5.7 1.3e-08 34.6 5.7 3.1 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KFX87529.1 - 5.6e-07 29.4 3.9 5.6e-07 29.4 3.9 2.9 2 1 0 2 2 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 KFX87529.1 - 1.1e-06 28.5 7.7 1.1e-06 28.5 7.7 2.3 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_2 PF13639.6 KFX87529.1 - 2e-06 28.0 5.2 2e-06 28.0 5.2 3.1 2 1 1 3 3 1 1 Ring finger domain zf-C3HC4 PF00097.25 KFX87529.1 - 2.1e-06 27.5 5.2 2.1e-06 27.5 5.2 2.8 2 1 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KFX87529.1 - 1.5e-05 24.7 3.6 1.5e-05 24.7 3.6 3.0 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-TRAF_2 PF15965.5 KFX87529.1 - 2e-05 25.0 15.9 0.0035 17.8 4.9 2.9 2 1 0 2 2 2 2 TRAF-like zinc-finger Prok-RING_4 PF14447.6 KFX87529.1 - 4.9e-05 23.1 6.0 4.9e-05 23.1 6.0 3.2 2 1 1 3 3 3 1 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 KFX87529.1 - 7.3e-05 22.8 7.0 7.3e-05 22.8 7.0 2.4 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_10 PF16685.5 KFX87529.1 - 0.00059 19.9 3.1 0.00059 19.9 3.1 2.4 2 1 0 2 2 1 1 zinc RING finger of MSL2 Sina PF03145.16 KFX87529.1 - 0.38 10.7 12.0 0.57 10.1 0.1 2.8 2 1 0 2 2 2 0 Seven in absentia protein family zf-Nse PF11789.8 KFX87529.1 - 0.45 10.4 11.7 3.7 7.4 11.7 2.6 1 1 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit C1_2 PF03107.16 KFX87534.1 - 0.096 13.0 0.1 0.096 13.0 0.1 2.3 2 0 0 2 2 2 0 C1 domain Mpv17_PMP22 PF04117.12 KFX87535.1 - 2.3e-09 37.3 1.4 5.6e-09 36.1 1.1 1.8 2 0 0 2 2 2 1 Mpv17 / PMP22 family DUF3278 PF11683.8 KFX87535.1 - 0.063 13.4 3.2 0.27 11.3 1.0 2.1 1 1 0 2 2 2 0 Protein of unknown function (DUF3278) NADH_oxidored PF08040.11 KFX87535.1 - 0.14 11.8 0.1 0.44 10.3 0.0 1.8 2 0 0 2 2 2 0 MNLL subunit Glyco_hydro_88 PF07470.13 KFX87550.1 - 2.6e-10 39.9 0.1 4.1e-10 39.3 0.1 1.3 1 0 0 1 1 1 1 Glycosyl Hydrolase Family 88 Sugar_tr PF00083.24 KFX87551.1 - 1.5e-88 297.6 19.9 1.8e-88 297.4 19.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KFX87551.1 - 4.8e-36 124.4 35.7 1e-30 106.9 17.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily PUCC PF03209.15 KFX87551.1 - 0.0018 17.4 4.7 0.0018 17.4 4.7 2.2 2 0 0 2 2 2 1 PUCC protein V-SNARE PF05008.15 KFX87563.1 - 9.7e-22 77.2 4.3 1.3e-21 76.7 4.3 1.2 1 0 0 1 1 1 1 Vesicle transport v-SNARE protein N-terminus DUF1542 PF07564.11 KFX87563.1 - 0.04 14.0 1.5 0.065 13.4 0.3 1.8 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1542) FAM76 PF16046.5 KFX87563.1 - 0.089 12.1 0.6 0.099 12.0 0.6 1.1 1 0 0 1 1 1 0 FAM76 protein Transp_cyt_pur PF02133.15 KFX87564.1 - 8.3e-48 163.2 35.2 9.6e-48 163.0 35.2 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin DUF3040 PF11239.8 KFX87564.1 - 1.2 9.5 0.0 1.2 9.5 0.0 4.7 4 1 0 5 5 5 0 Protein of unknown function (DUF3040) Pectate_lyase PF03211.13 KFX87565.1 - 1.3e-88 295.9 8.9 1.5e-88 295.7 8.9 1.1 1 0 0 1 1 1 1 Pectate lyase GFO_IDH_MocA PF01408.22 KFX87572.1 - 2.9e-22 79.7 0.1 7.8e-22 78.3 0.0 1.7 2 0 0 2 2 2 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 KFX87572.1 - 5.7e-06 26.3 0.0 4.3e-05 23.5 0.0 2.2 2 0 0 2 2 2 1 Oxidoreductase family, C-terminal alpha/beta domain NAD_binding_3 PF03447.16 KFX87572.1 - 0.00094 19.8 0.0 0.0018 18.9 0.0 1.4 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain AAA_33 PF13671.6 KFX87572.1 - 0.15 12.2 0.0 0.77 9.9 0.0 1.9 1 1 1 2 2 2 0 AAA domain Crystall PF00030.19 KFX87573.1 - 0.0015 18.7 0.0 0.78 10.0 0.0 2.4 2 0 0 2 2 2 2 Beta/Gamma crystallin Spc29 PF17082.5 KFX87574.1 - 0.073 12.9 17.8 1.9 8.3 5.7 4.1 2 2 2 4 4 4 0 Spindle Pole Component 29 Spc7 PF08317.11 KFX87574.1 - 0.36 9.7 51.0 0.058 12.3 5.4 4.6 3 1 1 4 4 4 0 Spc7 kinetochore protein ParD_antitoxin PF03693.14 KFX87574.1 - 0.76 10.2 4.1 7 7.1 0.3 3.3 2 1 0 2 2 2 0 Bacterial antitoxin of ParD toxin-antitoxin type II system and RHH IF-2B PF01008.17 KFX87574.1 - 1.9 7.7 9.1 1.9 7.6 3.7 2.7 1 1 0 2 2 2 0 Initiation factor 2 subunit family FlaC_arch PF05377.11 KFX87574.1 - 3.2 8.2 16.6 13 6.3 0.3 6.2 5 1 1 6 6 6 0 Flagella accessory protein C (FlaC) DUF1664 PF07889.12 KFX87574.1 - 5.8 7.0 27.4 0.03 14.4 2.4 5.3 5 2 1 6 6 6 0 Protein of unknown function (DUF1664) Exo_endo_phos PF03372.23 KFX87577.1 - 8.3e-09 35.3 0.0 1.7e-08 34.3 0.0 1.5 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Lantibiotic_a PF14867.6 KFX87577.1 - 0.33 10.7 1.2 0.85 9.4 0.6 1.9 2 0 0 2 2 2 0 Lantibiotic alpha MmoB_DmpM PF02406.17 KFX87578.1 - 0.013 15.7 0.0 0.027 14.7 0.0 1.6 1 0 0 1 1 1 0 MmoB/DmpM family adh_short_C2 PF13561.6 KFX87579.1 - 1.7e-52 178.3 6.5 4.5e-52 176.9 6.5 1.6 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KFX87579.1 - 5.6e-31 107.5 5.1 3.5e-30 104.9 5.1 1.9 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KFX87579.1 - 8.2e-08 32.4 0.6 2.4e-06 27.6 0.1 2.1 2 0 0 2 2 2 1 KR domain 2-Hacid_dh_C PF02826.19 KFX87579.1 - 0.0043 16.4 0.4 0.012 15.0 0.1 1.8 2 1 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain RmlD_sub_bind PF04321.17 KFX87579.1 - 0.0062 15.7 2.7 0.09 11.9 0.9 2.1 2 0 0 2 2 2 1 RmlD substrate binding domain Sacchrp_dh_NADP PF03435.18 KFX87579.1 - 0.014 15.6 0.3 0.026 14.8 0.3 1.4 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Epimerase PF01370.21 KFX87579.1 - 0.026 14.0 0.1 0.12 11.8 0.0 1.9 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family 3HCDH_N PF02737.18 KFX87579.1 - 0.029 14.3 0.6 0.047 13.6 0.6 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ApbA PF02558.16 KFX87579.1 - 0.042 13.5 0.1 0.081 12.6 0.1 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA NAD_Gly3P_dh_N PF01210.23 KFX87579.1 - 0.1 12.6 1.0 0.16 11.9 0.3 1.6 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus DUF3150 PF11348.8 KFX87579.1 - 0.12 11.6 0.1 0.2 10.8 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3150) HCV_NS5a_1a PF08300.13 KFX87580.1 - 0.073 13.2 0.1 0.18 11.9 0.1 1.6 1 0 0 1 1 1 0 Hepatitis C virus non-structural 5a zinc finger domain HisG PF01634.18 KFX87581.1 - 3.1e-53 180.0 0.1 6e-53 179.1 0.0 1.5 2 0 0 2 2 2 1 ATP phosphoribosyltransferase HisG_C PF08029.11 KFX87581.1 - 1.2e-28 99.0 0.2 2.2e-28 98.2 0.2 1.4 1 0 0 1 1 1 1 HisG, C-terminal domain DUF737 PF05300.11 KFX87583.1 - 5.9 7.2 11.2 1.4 9.3 7.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF737) HET PF06985.11 KFX87586.1 - 9.8e-28 97.3 0.3 1.7e-27 96.6 0.3 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) PAPS_reduct PF01507.19 KFX87588.1 - 2e-08 34.5 0.0 2.9e-08 34.0 0.0 1.2 1 0 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family Pectate_lyase_3 PF12708.7 KFX87589.1 - 2.9e-95 318.2 18.9 6.1e-77 258.3 6.9 3.7 3 0 0 3 3 3 3 Pectate lyase superfamily protein PAN_3 PF08277.12 KFX87589.1 - 3.8e-06 26.6 25.2 0.17 11.7 0.8 5.1 4 0 0 4 4 4 4 PAN-like domain End_N_terminal PF12218.8 KFX87589.1 - 1.9e-05 24.2 7.2 0.045 13.4 0.1 3.4 3 0 0 3 3 3 2 N terminal extension of bacteriophage endosialidase Pro_isomerase PF00160.21 KFX87600.1 - 3.3e-51 173.7 0.0 3.7e-51 173.5 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Peptidase_A22B PF04258.13 KFX87601.1 - 1.8e-57 195.1 0.5 3.5e-57 194.1 0.5 1.4 1 1 0 1 1 1 1 Signal peptide peptidase SPP PF06550.11 KFX87601.1 - 0.0053 16.3 14.0 0.12 11.9 9.5 3.0 2 1 0 2 2 2 1 Signal-peptide peptidase, presenilin aspartyl protease Presenilin PF01080.17 KFX87601.1 - 1.2 7.8 6.3 0.69 8.6 0.4 2.9 2 1 1 3 3 3 0 Presenilin AMP-binding_C PF13193.6 KFX87603.1 - 1.4e-16 61.2 0.0 1.1e-15 58.4 0.0 2.1 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain Polyketide_cyc PF03364.20 KFX87608.1 - 1.2e-23 83.7 0.0 2.8e-23 82.6 0.0 1.6 1 1 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc2 PF10604.9 KFX87608.1 - 0.0056 17.0 0.0 0.13 12.5 0.0 2.1 2 0 0 2 2 2 1 Polyketide cyclase / dehydrase and lipid transport Methyltransf_12 PF08242.12 KFX87609.1 - 8.9e-16 58.5 0.0 2.2e-15 57.2 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KFX87609.1 - 1.3e-15 57.9 0.0 2.4e-15 57.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KFX87609.1 - 2.3e-12 47.4 0.0 4.5e-12 46.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KFX87609.1 - 1.8e-11 44.1 0.0 2.4e-11 43.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KFX87609.1 - 2.2e-08 34.0 0.0 3.9e-08 33.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KFX87609.1 - 3.5e-08 33.1 0.0 5.4e-08 32.5 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.14 KFX87609.1 - 0.00065 19.3 0.0 0.0011 18.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_24 PF13578.6 KFX87609.1 - 0.0048 17.9 0.0 0.0097 16.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_16 PF10294.9 KFX87609.1 - 0.0082 15.9 0.0 0.012 15.3 0.0 1.2 1 0 0 1 1 1 1 Lysine methyltransferase PrmA PF06325.13 KFX87609.1 - 0.0093 15.4 0.0 0.014 14.8 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Roc PF08477.13 KFX87609.1 - 0.015 15.5 0.7 6.8 6.9 0.0 2.5 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase NNMT_PNMT_TEMT PF01234.17 KFX87609.1 - 0.015 14.5 0.0 0.5 9.5 0.0 2.2 1 1 1 2 2 2 0 NNMT/PNMT/TEMT family Methyltransf_8 PF05148.15 KFX87609.1 - 0.016 15.1 0.0 0.054 13.3 0.0 1.8 1 1 1 2 2 2 0 Hypothetical methyltransferase DUF3419 PF11899.8 KFX87609.1 - 0.019 14.1 0.0 0.031 13.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3419) Methyltransf_2 PF00891.18 KFX87609.1 - 0.12 11.7 0.0 0.23 10.7 0.0 1.4 1 0 0 1 1 1 0 O-methyltransferase domain Methyltransf_32 PF13679.6 KFX87609.1 - 0.22 11.5 0.0 0.38 10.7 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain CDH-cyt PF16010.5 KFX87610.1 - 1.5e-49 168.2 0.0 1.8e-49 167.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome domain of cellobiose dehydrogenase NOA36 PF06524.12 KFX87610.1 - 0.011 15.0 14.0 0.011 15.0 14.0 1.9 2 0 0 2 2 2 0 NOA36 protein CDC45 PF02724.14 KFX87610.1 - 0.2 9.9 3.8 0.27 9.5 3.8 1.1 1 0 0 1 1 1 0 CDC45-like protein SDA1 PF05285.12 KFX87610.1 - 0.37 10.2 8.8 0.47 9.8 8.8 1.1 1 0 0 1 1 1 0 SDA1 DNA_pol_phi PF04931.13 KFX87610.1 - 0.75 7.8 19.2 1 7.4 19.2 1.1 1 0 0 1 1 1 0 DNA polymerase phi RRN3 PF05327.11 KFX87610.1 - 0.97 7.9 5.3 1.2 7.6 5.3 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Nop14 PF04147.12 KFX87610.1 - 1.8 6.7 7.0 2.3 6.3 7.0 1.1 1 0 0 1 1 1 0 Nop14-like family PPP4R2 PF09184.11 KFX87610.1 - 6 6.4 7.6 11 5.5 7.6 1.3 1 0 0 1 1 1 0 PPP4R2 TRAPP PF04051.16 KFX87614.1 - 4.1e-36 123.9 0.0 4.8e-36 123.7 0.0 1.0 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component Ldh_1_C PF02866.18 KFX87615.1 - 4.5e-46 156.8 0.0 6.6e-46 156.3 0.0 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Ldh_1_N PF00056.23 KFX87615.1 - 2.6e-44 150.7 0.2 3.7e-44 150.3 0.2 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain 3Beta_HSD PF01073.19 KFX87615.1 - 0.00099 18.2 0.0 0.0014 17.7 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family THF_DHG_CYH_C PF02882.19 KFX87615.1 - 0.036 13.4 0.2 0.22 10.8 0.2 2.2 1 1 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Peptidase_M36 PF02128.15 KFX87633.1 - 6e-162 539.0 3.4 7.6e-162 538.7 3.4 1.1 1 0 0 1 1 1 1 Fungalysin metallopeptidase (M36) FTP PF07504.13 KFX87633.1 - 7.4e-17 60.9 4.2 1.8e-16 59.7 4.2 1.7 1 0 0 1 1 1 1 Fungalysin/Thermolysin Propeptide Motif Peptidase_M4_C PF02868.15 KFX87633.1 - 0.04 13.8 0.0 0.12 12.3 0.0 1.8 2 0 0 2 2 2 0 Thermolysin metallopeptidase, alpha-helical domain ComA PF02679.15 KFX87636.1 - 7e-90 300.7 0.0 8.3e-90 300.5 0.0 1.0 1 0 0 1 1 1 1 (2R)-phospho-3-sulfolactate synthase (ComA) DUF2542 PF10808.8 KFX87636.1 - 0.16 12.5 0.0 0.29 11.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2542) AAA PF00004.29 KFX87645.1 - 1.1e-42 145.5 0.1 2.8e-42 144.2 0.0 1.7 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KFX87645.1 - 4.7e-09 35.9 0.0 1.1e-08 34.7 0.0 1.6 1 0 0 1 1 1 1 AAA+ lid domain RuvB_N PF05496.12 KFX87645.1 - 5.7e-08 32.7 0.0 9.8e-08 31.9 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 KFX87645.1 - 8.9e-06 26.2 0.0 5.8e-05 23.5 0.0 2.3 2 1 0 2 2 2 1 AAA ATPase domain AAA_5 PF07728.14 KFX87645.1 - 2.4e-05 24.4 0.1 0.00026 21.0 0.1 2.4 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 KFX87645.1 - 7.5e-05 22.9 0.0 0.00023 21.3 0.0 1.8 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_25 PF13481.6 KFX87645.1 - 0.00016 21.3 0.7 0.56 9.8 0.0 3.2 2 1 0 3 3 3 2 AAA domain AAA_22 PF13401.6 KFX87645.1 - 0.00032 21.0 0.3 0.011 16.0 0.0 3.0 2 1 0 2 2 2 1 AAA domain ATPase PF06745.13 KFX87645.1 - 0.00057 19.3 0.1 0.018 14.4 0.0 2.5 2 0 0 2 2 2 1 KaiC AAA_14 PF13173.6 KFX87645.1 - 0.00082 19.4 0.0 0.0055 16.8 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_7 PF12775.7 KFX87645.1 - 0.0013 18.2 0.0 0.0088 15.6 0.0 2.2 2 1 0 2 2 2 1 P-loop containing dynein motor region IstB_IS21 PF01695.17 KFX87645.1 - 0.0017 18.1 0.0 0.0049 16.6 0.0 1.7 1 1 1 2 2 2 1 IstB-like ATP binding protein Cytidylate_kin2 PF13189.6 KFX87645.1 - 0.0022 18.1 0.0 0.0068 16.6 0.0 1.7 2 0 0 2 2 2 1 Cytidylate kinase-like family AAA_33 PF13671.6 KFX87645.1 - 0.0023 18.1 0.0 0.0095 16.1 0.0 2.0 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 KFX87645.1 - 0.0027 18.1 0.0 0.0095 16.3 0.0 2.0 1 1 0 1 1 1 1 RNA helicase TIP49 PF06068.13 KFX87645.1 - 0.0028 16.9 0.1 0.0064 15.7 0.1 1.6 1 1 0 1 1 1 1 TIP49 P-loop domain TniB PF05621.11 KFX87645.1 - 0.0033 16.9 0.1 0.08 12.3 0.0 2.5 1 1 1 2 2 2 1 Bacterial TniB protein AAA_3 PF07726.11 KFX87645.1 - 0.0039 17.0 0.0 0.0079 16.1 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Mg_chelatase PF01078.21 KFX87645.1 - 0.0073 15.7 0.0 0.016 14.6 0.0 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_28 PF13521.6 KFX87645.1 - 0.0078 16.5 0.0 0.017 15.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain NACHT PF05729.12 KFX87645.1 - 0.0082 16.1 0.0 0.065 13.2 0.0 2.3 2 1 0 2 2 2 1 NACHT domain Rad17 PF03215.15 KFX87645.1 - 0.0083 16.1 0.0 0.014 15.3 0.0 1.4 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_17 PF13207.6 KFX87645.1 - 0.02 15.3 0.6 0.73 10.3 0.1 2.9 2 1 0 2 2 2 0 AAA domain AAA_18 PF13238.6 KFX87645.1 - 0.046 14.3 0.0 0.13 12.8 0.0 1.8 1 0 0 1 1 1 0 AAA domain AFG1_ATPase PF03969.16 KFX87645.1 - 0.056 12.3 0.0 0.12 11.2 0.0 1.5 1 1 0 1 1 1 0 AFG1-like ATPase Zeta_toxin PF06414.12 KFX87645.1 - 0.059 12.6 0.0 0.19 11.0 0.0 1.8 1 0 0 1 1 1 0 Zeta toxin TsaE PF02367.17 KFX87645.1 - 0.087 12.8 0.0 0.17 11.9 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Disulph_isomer PF06491.11 KFX87645.1 - 0.092 12.9 0.1 0.24 11.5 0.1 1.7 1 0 0 1 1 1 0 Disulphide isomerase Snf7 PF03357.21 KFX87646.1 - 6e-33 113.9 10.5 7.5e-33 113.5 10.5 1.2 1 0 0 1 1 1 1 Snf7 YlqD PF11068.8 KFX87646.1 - 0.96 9.8 10.2 6 7.2 2.5 2.4 2 1 0 2 2 2 0 YlqD protein Cytochrom_C PF00034.21 KFX87647.1 - 2.8e-10 41.2 0.0 3.9e-10 40.7 0.0 1.2 1 0 0 1 1 1 1 Cytochrome c Cytochrome_CBB3 PF13442.6 KFX87647.1 - 1.8e-08 34.6 0.3 8.9e-08 32.3 0.3 1.8 1 1 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C550 PF14495.6 KFX87647.1 - 0.00022 21.0 0.1 0.0015 18.3 0.1 2.0 2 0 0 2 2 2 1 Cytochrome c-550 domain Flavokinase PF01687.17 KFX87664.1 - 2.6e-33 114.7 0.0 3e-33 114.5 0.0 1.0 1 0 0 1 1 1 1 Riboflavin kinase Zn_clus PF00172.18 KFX87665.1 - 0.0062 16.6 9.6 0.0062 16.6 9.6 1.8 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PAS PF00989.25 KFX87665.1 - 0.014 15.4 0.0 0.04 13.9 0.0 1.7 2 0 0 2 2 2 0 PAS fold CbiJ PF02571.14 KFX87665.1 - 0.06 12.8 0.0 0.095 12.2 0.0 1.2 1 0 0 1 1 1 0 Precorrin-6x reductase CbiJ/CobK PX PF00787.24 KFX87668.1 - 1.1e-21 77.0 0.0 1.4e-21 76.6 0.0 1.1 1 0 0 1 1 1 1 PX domain LtuB PF17455.2 KFX87668.1 - 0.12 13.0 0.0 0.2 12.3 0.0 1.3 1 0 0 1 1 1 0 Late transcription unit B IQ PF00612.27 KFX87669.1 - 0.0022 17.6 2.8 0.0056 16.4 2.8 1.8 1 0 0 1 1 1 1 IQ calmodulin-binding motif 2-oxoacid_dh PF00198.23 KFX87672.1 - 3.1e-76 255.9 0.7 7.6e-76 254.6 0.3 1.7 2 0 0 2 2 2 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 KFX87672.1 - 3.9e-19 68.3 0.0 8.1e-19 67.2 0.0 1.6 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.17 KFX87672.1 - 2.7e-14 53.2 0.3 8.2e-14 51.7 0.3 1.8 1 0 0 1 1 1 1 e3 binding domain HlyD_D23 PF16576.5 KFX87672.1 - 0.0045 16.2 0.0 0.0081 15.4 0.0 1.4 1 0 0 1 1 1 1 Barrel-sandwich domain of CusB or HlyD membrane-fusion Biotin_lipoyl_2 PF13533.6 KFX87672.1 - 0.054 13.3 0.0 0.27 11.1 0.0 2.2 1 1 1 2 2 2 0 Biotin-lipoyl like MiAMP1 PF09117.10 KFX87676.1 - 0.013 15.7 0.1 0.017 15.3 0.1 1.3 1 0 0 1 1 1 0 MiAMP1 Baseplate_J PF04865.14 KFX87676.1 - 0.087 12.0 0.0 0.1 11.7 0.0 1.1 1 0 0 1 1 1 0 Baseplate J-like protein His_Phos_1 PF00300.22 KFX87678.1 - 5.8e-27 94.6 0.0 1.4e-26 93.4 0.0 1.6 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) VGCC_beta4Aa_N PF12052.8 KFX87678.1 - 0.0057 16.7 1.3 0.0057 16.7 1.3 2.4 2 0 0 2 2 2 1 Voltage gated calcium channel subunit beta domain 4Aa N terminal zf-C2H2 PF00096.26 KFX87684.1 - 9.7e-14 51.0 20.6 3.9e-05 23.9 1.8 4.3 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KFX87684.1 - 1.6e-09 37.7 20.7 6.1e-09 35.9 0.7 4.5 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 KFX87684.1 - 6.2e-07 29.7 14.4 0.089 13.7 0.0 4.0 3 0 0 3 3 3 3 C2H2-type zinc finger zf-met PF12874.7 KFX87684.1 - 0.027 14.9 0.6 3.9 8.0 0.0 3.2 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-C2H2_aberr PF17017.5 KFX87684.1 - 0.038 14.1 0.5 0.038 14.1 0.5 3.1 2 1 0 3 3 3 0 Aberrant zinc-finger GAGA PF09237.11 KFX87684.1 - 0.047 13.5 0.6 7.1 6.5 0.2 2.5 1 1 1 2 2 2 0 GAGA factor TFIIA PF03153.13 KFX87684.1 - 0.056 13.4 19.5 0.079 13.0 19.5 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit CCSAP PF15748.5 KFX87684.1 - 1 9.4 9.0 1.7 8.7 9.0 1.3 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated CFEM PF05730.11 KFX87687.1 - 2.2e-09 37.3 10.1 4.3e-09 36.3 10.1 1.5 1 0 0 1 1 1 1 CFEM domain Cyclin_C_2 PF16899.5 KFX87688.1 - 0.01 16.2 0.2 0.025 14.9 0.1 1.7 2 0 0 2 2 2 0 Cyclin C-terminal domain Histone PF00125.24 KFX87691.1 - 5.2e-52 175.7 2.5 5.9e-52 175.5 2.5 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.6 KFX87691.1 - 5.6e-06 26.6 0.1 8.4e-06 26.1 0.1 1.2 1 0 0 1 1 1 1 CENP-S protein PAF PF15715.5 KFX87691.1 - 3.4e-05 24.4 0.9 4.3e-05 24.1 0.9 1.2 1 0 0 1 1 1 1 PCNA-associated factor histone like domain CENP-T_C PF15511.6 KFX87691.1 - 4.9e-05 23.4 0.8 6.7e-05 23.0 0.1 1.5 2 0 0 2 2 2 1 Centromere kinetochore component CENP-T histone fold CBFD_NFYB_HMF PF00808.23 KFX87691.1 - 0.0045 17.2 0.4 0.0077 16.5 0.0 1.5 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 KFX87691.1 - 0.025 14.6 0.3 0.039 14.0 0.1 1.5 2 0 0 2 2 2 0 Transcription initiation factor IID, 31kD subunit Zn_clus PF00172.18 KFX87693.1 - 6.8e-10 38.9 7.8 1.6e-09 37.7 7.8 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 KFX87693.1 - 4.1e-06 25.9 0.0 7e-06 25.1 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain CUE PF02845.16 KFX87702.1 - 3.7e-11 42.5 0.0 6.1e-11 41.8 0.0 1.3 1 0 0 1 1 1 1 CUE domain BacteriocIIc_cy PF12173.8 KFX87702.1 - 0.31 11.3 2.7 0.49 10.7 2.7 1.3 1 0 0 1 1 1 0 Bacteriocin class IIc cyclic gassericin A-like DUF1996 PF09362.10 KFX87728.1 - 1.9e-90 302.9 1.6 2.8e-90 302.4 1.6 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) TPR_2 PF07719.17 KFX87729.1 - 7.8e-07 28.7 0.0 0.28 11.4 0.0 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat F-box-like PF12937.7 KFX87729.1 - 1.9e-06 27.7 0.1 3.9e-06 26.7 0.1 1.6 1 0 0 1 1 1 1 F-box-like TPR_12 PF13424.6 KFX87729.1 - 5.8e-05 23.3 0.4 0.17 12.2 0.0 3.0 2 1 1 3 3 3 2 Tetratricopeptide repeat F-box PF00646.33 KFX87729.1 - 0.00011 22.0 0.0 0.00038 20.3 0.0 2.0 2 0 0 2 2 2 1 F-box domain TPR_1 PF00515.28 KFX87729.1 - 0.00087 19.0 0.0 0.9 9.5 0.0 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat LRR_4 PF12799.7 KFX87729.1 - 0.0025 18.2 15.1 0.34 11.4 1.9 6.4 6 2 1 7 7 7 1 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KFX87729.1 - 0.1 12.4 5.9 1.1 9.1 2.0 4.3 5 1 0 5 5 5 0 Leucine rich repeat TPR_11 PF13414.6 KFX87729.1 - 0.14 11.9 0.0 1 9.1 0.0 2.3 2 1 0 2 2 2 0 TPR repeat DUF1858 PF08984.11 KFX87729.1 - 0.18 12.0 0.0 8.5 6.6 0.0 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF1858) CTNNBL PF08216.11 KFX87730.1 - 3.7e-40 136.3 0.9 6.9e-40 135.4 0.0 2.0 2 0 0 2 2 2 1 Catenin-beta-like, Arm-motif containing nuclear SpecificRecomb PF10136.9 KFX87730.1 - 0.0037 15.6 0.1 0.0059 15.0 0.1 1.3 1 0 0 1 1 1 1 Site-specific recombinase Arm PF00514.23 KFX87730.1 - 0.013 15.6 0.0 1.3 9.2 0.0 3.2 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat DUF5578 PF17741.1 KFX87730.1 - 0.036 13.5 0.6 3.1 7.1 0.0 2.5 2 0 0 2 2 2 0 Family of unknown function (DUF5578) Mo25 PF08569.11 KFX87730.1 - 0.066 12.6 0.5 0.12 11.7 0.1 1.6 2 0 0 2 2 2 0 Mo25-like Sugar_tr PF00083.24 KFX87731.1 - 8.7e-71 239.1 18.2 1e-70 238.9 18.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KFX87731.1 - 1.2e-13 50.8 26.2 1.2e-13 50.8 26.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 KFX87731.1 - 3.4e-07 29.2 14.4 0.00015 20.4 3.6 2.4 2 0 0 2 2 2 2 MFS/sugar transport protein MFS_1_like PF12832.7 KFX87731.1 - 0.00054 18.9 2.8 0.00054 18.9 2.8 2.3 2 0 0 2 2 2 1 MFS_1 like family DUF2301 PF10063.9 KFX87731.1 - 0.086 13.3 0.5 15 6.0 0.2 2.6 2 0 0 2 2 2 0 Uncharacterized integral membrane protein (DUF2301) HNH_2 PF13391.6 KFX87736.1 - 4.9e-16 58.6 0.0 8.8e-16 57.8 0.0 1.4 1 0 0 1 1 1 1 HNH endonuclease E1-E2_ATPase PF00122.20 KFX87737.1 - 3.3e-51 173.4 0.5 1.2e-50 171.5 0.5 2.0 1 0 0 1 1 1 1 E1-E2 ATPase HMA PF00403.26 KFX87737.1 - 1.1e-49 166.7 0.1 8.3e-13 48.6 0.1 4.5 4 0 0 4 4 4 4 Heavy-metal-associated domain Hydrolase PF00702.26 KFX87737.1 - 8.1e-40 137.3 2.8 3.9e-39 135.1 1.3 2.6 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 KFX87737.1 - 4e-05 23.5 3.2 6.3e-05 22.8 1.3 2.0 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase CDCA PF18484.1 KFX87737.1 - 0.0039 17.1 0.8 22 4.9 0.0 3.9 3 1 1 4 4 4 1 Cadmium carbonic anhydrase repeat Phage_tail_2 PF06199.11 KFX87737.1 - 0.09 12.9 1.5 0.28 11.3 0.1 2.5 3 0 0 3 3 3 0 Phage tail tube protein zinc_ribbon_12 PF11331.8 KFX87737.1 - 0.15 11.9 3.0 23 4.9 0.1 3.3 3 0 0 3 3 3 0 Probable zinc-ribbon domain DUF1656 PF07869.12 KFX87737.1 - 4.3 7.4 6.3 4.6 7.3 0.5 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF1656) TPR_10 PF13374.6 KFX87738.1 - 4.4e-16 58.2 20.1 0.0098 15.7 0.0 9.8 11 0 0 11 11 11 5 Tetratricopeptide repeat TPR_8 PF13181.6 KFX87738.1 - 0.00075 19.5 0.5 21 5.6 0.0 6.1 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_14 PF13428.6 KFX87738.1 - 0.0025 18.5 6.4 7.2 7.7 0.0 6.4 5 1 1 6 6 6 1 Tetratricopeptide repeat DUF4164 PF13747.6 KFX87738.1 - 0.036 14.3 1.6 31 4.9 0.1 4.5 3 1 1 4 4 4 0 Domain of unknown function (DUF4164) TPR_2 PF07719.17 KFX87738.1 - 0.7 10.2 9.2 73 3.9 0.0 6.9 8 0 0 8 8 8 0 Tetratricopeptide repeat Halo_GVPC PF05465.13 KFX87738.1 - 3.7 7.9 4.2 12 6.2 0.0 3.0 3 0 0 3 3 3 0 Halobacterial gas vesicle protein C (GVPC) repeat O-FucT PF10250.9 KFX87739.1 - 2.9e-16 60.1 0.0 1.5e-14 54.5 0.0 2.7 1 1 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase PCI PF01399.27 KFX87740.1 - 0.00038 20.9 0.0 0.00065 20.2 0.0 1.4 1 0 0 1 1 1 1 PCI domain CSN7a_helixI PF18392.1 KFX87740.1 - 0.00049 19.9 0.1 0.00084 19.2 0.1 1.4 1 0 0 1 1 1 1 COP9 signalosome complex subunit 7a helix I domain Kdo PF06293.14 KFX87744.1 - 0.052 12.9 0.0 0.083 12.2 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Hydrolase_4 PF12146.8 KFX87745.1 - 0.00011 21.5 0.0 0.00021 20.7 0.0 1.4 1 1 0 1 1 1 1 Serine aminopeptidase, S33 FHA PF00498.26 KFX87750.1 - 3.1e-12 46.7 0.0 9.7e-12 45.1 0.0 1.9 1 0 0 1 1 1 1 FHA domain IFRD PF05004.13 KFX87751.1 - 1.1e-83 280.9 8.8 1.4e-83 280.5 8.8 1.1 1 0 0 1 1 1 1 Interferon-related developmental regulator (IFRD) HEAT_2 PF13646.6 KFX87751.1 - 0.00044 20.6 2.1 0.14 12.5 0.1 2.5 1 1 1 2 2 2 2 HEAT repeats FAA_hydro_N_2 PF18288.1 KFX87751.1 - 0.17 12.3 1.8 0.26 11.7 0.3 2.0 2 0 0 2 2 2 0 Fumarylacetoacetase N-terminal domain 2 RAP1 PF07218.11 KFX87751.1 - 0.43 8.8 4.4 0.62 8.3 4.4 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) LIP PF03583.14 KFX87770.1 - 9.2e-22 77.7 0.1 1.3e-21 77.2 0.1 1.1 1 0 0 1 1 1 1 Secretory lipase Hydrolase_4 PF12146.8 KFX87770.1 - 1.6e-06 27.6 0.0 2.6e-06 26.9 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KFX87770.1 - 2.8e-06 28.1 1.7 3.6e-06 27.8 0.2 1.8 1 1 1 2 2 2 1 Alpha/beta hydrolase family Esterase PF00756.20 KFX87770.1 - 0.0033 17.1 0.1 0.01 15.5 0.0 1.7 2 0 0 2 2 2 1 Putative esterase Lipase_3 PF01764.25 KFX87770.1 - 0.0095 15.8 0.0 0.015 15.2 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) DUF1749 PF08538.10 KFX87770.1 - 0.012 14.7 0.0 0.019 14.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1749) DUF2974 PF11187.8 KFX87770.1 - 0.014 14.9 0.0 0.023 14.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Chlorophyllase2 PF12740.7 KFX87770.1 - 0.034 13.1 0.0 0.069 12.1 0.0 1.5 1 0 0 1 1 1 0 Chlorophyllase enzyme Chlorophyllase PF07224.11 KFX87770.1 - 0.035 13.1 0.0 0.058 12.4 0.0 1.4 1 0 0 1 1 1 0 Chlorophyllase Peptidase_S9 PF00326.21 KFX87770.1 - 0.041 13.3 0.0 0.066 12.7 0.0 1.2 1 0 0 1 1 1 0 Prolyl oligopeptidase family DUF3089 PF11288.8 KFX87770.1 - 0.042 13.4 0.0 0.067 12.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3089) Abhydrolase_2 PF02230.16 KFX87770.1 - 0.057 13.2 0.0 0.094 12.5 0.0 1.3 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase Abhydrolase_1 PF00561.20 KFX87770.1 - 0.064 12.9 0.0 0.095 12.3 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_3 PF07859.13 KFX87770.1 - 0.12 12.3 0.0 0.16 11.8 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold Cutinase PF01083.22 KFX87770.1 - 0.18 11.7 0.0 0.26 11.2 0.0 1.2 1 0 0 1 1 1 0 Cutinase DUF1057 PF06342.12 KFX87770.1 - 0.21 10.6 0.0 0.38 9.7 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1057) Aldo_ket_red PF00248.21 KFX87774.1 - 7.3e-17 61.5 0.0 8.7e-17 61.2 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Rotamase PF00639.21 KFX87778.1 - 5.4e-13 49.7 0.0 7.3e-13 49.3 0.0 1.3 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_3 PF13616.6 KFX87778.1 - 7.7e-13 49.0 0.0 1.4e-12 48.2 0.0 1.4 1 1 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_2 PF13145.6 KFX87778.1 - 0.001 19.9 0.5 0.0021 18.9 0.5 1.6 1 1 0 1 1 1 1 PPIC-type PPIASE domain Methyltransf_2 PF00891.18 KFX87779.1 - 3.8e-18 65.6 0.0 6.2e-18 64.9 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase domain MarR_2 PF12802.7 KFX87779.1 - 0.11 12.4 0.0 0.25 11.3 0.0 1.5 1 0 0 1 1 1 0 MarR family FeoC PF09012.10 KFX87779.1 - 0.2 11.8 0.0 0.48 10.5 0.0 1.6 1 0 0 1 1 1 0 FeoC like transcriptional regulator SOR_SNZ PF01680.17 KFX87781.1 - 5.6e-110 366.0 6.9 5.6e-110 366.0 6.9 1.5 2 0 0 2 2 2 1 SOR/SNZ family ThiG PF05690.14 KFX87781.1 - 3.5e-08 33.0 7.7 6.5e-07 28.9 0.4 2.5 2 1 1 3 3 3 2 Thiazole biosynthesis protein ThiG Dus PF01207.17 KFX87781.1 - 0.013 14.7 1.0 0.84 8.7 0.1 2.7 2 1 1 3 3 3 0 Dihydrouridine synthase (Dus) His_biosynth PF00977.21 KFX87781.1 - 0.014 14.8 0.6 0.22 11.0 0.0 2.4 2 1 0 2 2 2 0 Histidine biosynthesis protein TetR_C_27 PF17935.1 KFX87781.1 - 0.02 14.9 0.0 0.055 13.5 0.0 1.7 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain NanE PF04131.14 KFX87781.1 - 0.022 13.9 0.9 0.15 11.2 0.0 2.4 2 1 0 2 2 2 0 Putative N-acetylmannosamine-6-phosphate epimerase IGPS PF00218.21 KFX87781.1 - 0.04 13.1 0.1 0.58 9.3 0.0 2.4 3 0 0 3 3 3 0 Indole-3-glycerol phosphate synthase LysM PF01476.20 KFX87782.1 - 2.7e-07 30.5 0.0 0.0011 19.0 0.0 3.1 3 0 0 3 3 3 2 LysM domain PAN_4 PF14295.6 KFX87782.1 - 1.1e-05 25.2 16.4 0.1 12.5 0.3 5.3 5 0 0 5 5 5 3 PAN domain PAN_3 PF08277.12 KFX87782.1 - 0.00015 21.5 12.7 0.16 11.8 0.1 4.8 5 0 0 5 5 5 3 PAN-like domain Toxin_28 PF08115.11 KFX87782.1 - 0.42 10.5 3.8 0.5 10.3 0.5 2.5 2 0 0 2 2 2 0 SFI toxin family FAD_binding_4 PF01565.23 KFX87785.1 - 1.2e-22 80.2 0.3 2e-22 79.4 0.3 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 KFX87785.1 - 0.0052 16.9 0.2 0.011 15.8 0.2 1.6 1 0 0 1 1 1 1 Berberine and berberine like DUF244 PF03112.14 KFX87786.1 - 0.076 12.9 0.1 0.12 12.2 0.1 1.2 1 0 0 1 1 1 0 Uncharacterized protein family (ORF7) DUF DUF3525 PF12039.8 KFX87786.1 - 0.84 8.3 3.5 0.79 8.4 0.2 2.1 2 1 1 3 3 3 0 Protein of unknown function (DUF3525) CDC27 PF09507.10 KFX87786.1 - 1.3 8.4 8.0 0.25 10.7 4.3 1.7 2 0 0 2 2 2 0 DNA polymerase subunit Cdc27 Dicty_REP PF05086.12 KFX87786.1 - 2.2 6.2 5.0 2.6 5.9 5.0 1.2 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Nop14 PF04147.12 KFX87786.1 - 3.4 5.7 6.7 4.3 5.4 6.7 1.1 1 0 0 1 1 1 0 Nop14-like family GET2 PF08690.10 KFX87786.1 - 7 6.2 6.7 6.3 6.4 5.4 1.6 1 1 0 1 1 1 0 GET complex subunit GET2 Spermine_synth PF01564.17 KFX87787.1 - 1e-75 253.3 0.0 1.5e-75 252.8 0.0 1.2 1 0 0 1 1 1 1 Spermine/spermidine synthase domain Spermine_synt_N PF17284.2 KFX87787.1 - 2.4e-26 91.4 0.1 4.3e-26 90.6 0.1 1.4 1 0 0 1 1 1 1 Spermidine synthase tetramerisation domain Methyltransf_25 PF13649.6 KFX87787.1 - 0.00019 22.0 0.0 0.00055 20.6 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain DUF43 PF01861.16 KFX87787.1 - 0.0027 17.0 0.0 0.0042 16.4 0.0 1.2 1 0 0 1 1 1 1 Branched-chain polyamine synthase A C-terminal domain Methyltransf_12 PF08242.12 KFX87787.1 - 0.0051 17.5 0.4 0.078 13.7 0.0 2.6 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_18 PF12847.7 KFX87787.1 - 0.03 14.2 0.0 0.055 13.4 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_30 PF05430.11 KFX87787.1 - 0.16 11.8 0.0 0.29 11.0 0.0 1.4 1 0 0 1 1 1 0 S-adenosyl-L-methionine-dependent methyltransferase DUF3993 PF13158.6 KFX87788.1 - 0.14 12.4 1.2 0.67 10.2 0.3 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3993) DASH_Dam1 PF08653.10 KFX87788.1 - 0.22 11.3 2.8 0.28 11.0 1.2 2.1 2 0 0 2 2 2 0 DASH complex subunit Dam1 Asn_synthase PF00733.21 KFX87790.1 - 2e-15 57.3 0.0 1.8e-05 24.6 0.0 3.1 2 1 1 3 3 3 3 Asparagine synthase GATase_7 PF13537.6 KFX87790.1 - 4.9e-07 29.7 0.0 1.6e-06 28.0 0.0 1.8 1 1 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.6 KFX87790.1 - 0.0002 21.6 0.0 0.0004 20.6 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain Sugar_tr PF00083.24 KFX87791.1 - 1.8e-97 327.1 26.0 2.2e-97 326.8 26.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KFX87791.1 - 1.1e-38 133.1 43.8 6.4e-35 120.7 20.4 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 KFX87791.1 - 0.0072 14.9 2.4 0.0072 14.9 2.4 3.5 2 2 1 3 3 3 2 MFS/sugar transport protein DNA_pol_B_palm PF14792.6 KFX87792.1 - 8e-33 113.1 0.0 1.4e-32 112.3 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase beta palm DNA_pol_B_thumb PF14791.6 KFX87792.1 - 9.8e-25 86.5 0.1 1.3e-23 82.9 0.0 2.3 2 0 0 2 2 2 1 DNA polymerase beta thumb DNA_pol_lambd_f PF10391.9 KFX87792.1 - 3.8e-18 65.1 0.4 8.3e-18 64.0 0.4 1.6 1 0 0 1 1 1 1 Fingers domain of DNA polymerase lambda HHH_8 PF14716.6 KFX87792.1 - 2e-16 60.1 1.1 3.8e-16 59.2 0.4 1.9 2 0 0 2 2 2 1 Helix-hairpin-helix domain HHH_2 PF12826.7 KFX87792.1 - 0.035 14.2 0.1 4.5 7.4 0.0 2.4 2 0 0 2 2 2 0 Helix-hairpin-helix motif PTCB-BRCT PF12738.7 KFX87792.1 - 0.092 12.7 0.0 0.19 11.7 0.0 1.4 1 0 0 1 1 1 0 twin BRCT domain HHH_5 PF14520.6 KFX87792.1 - 0.16 12.6 0.4 1.8 9.2 0.0 2.4 2 0 0 2 2 2 0 Helix-hairpin-helix domain BRCT PF00533.26 KFX87792.1 - 0.18 12.2 0.0 0.34 11.3 0.0 1.5 1 0 0 1 1 1 0 BRCA1 C Terminus (BRCT) domain 5_3_exonuc PF01367.20 KFX87792.1 - 0.19 12.3 0.3 2.7 8.7 0.0 2.3 2 0 0 2 2 2 0 5'-3' exonuclease, C-terminal SAM fold Acetyltransf_10 PF13673.7 KFX87793.1 - 1.4e-09 38.0 0.0 1.8e-09 37.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KFX87793.1 - 9.3e-08 32.3 0.0 1.3e-07 31.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KFX87793.1 - 1.3e-06 28.7 0.0 1.7e-06 28.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 KFX87793.1 - 0.00022 21.3 0.0 0.00032 20.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 KFX87793.1 - 0.0044 17.1 0.0 0.0081 16.3 0.0 1.4 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase FR47 PF08445.10 KFX87793.1 - 0.026 14.5 0.0 0.065 13.2 0.0 1.7 1 1 0 1 1 1 0 FR47-like protein Orai-1 PF07856.12 KFX87797.1 - 0.1 12.3 5.5 0.053 13.2 2.7 1.8 2 0 0 2 2 2 0 Mediator of CRAC channel activity MHYT PF03707.16 KFX87797.1 - 0.18 12.0 2.3 3.6 7.8 0.2 3.0 2 0 0 2 2 2 0 Bacterial signalling protein N terminal repeat SH2_2 PF14633.6 KFX87800.1 - 4e-55 186.6 1.5 9.9e-55 185.3 1.5 1.7 1 0 0 1 1 1 1 SH2 domain HTH_44 PF14641.6 KFX87800.1 - 1.7e-39 134.8 0.6 4.5e-39 133.4 0.1 2.1 2 0 0 2 2 2 1 Helix-turn-helix DNA-binding domain of SPT6 HHH_7 PF14635.6 KFX87800.1 - 8.4e-30 103.2 0.0 4.5e-29 100.9 0.0 2.2 2 0 0 2 2 2 1 Helix-hairpin-helix motif YqgF PF14639.6 KFX87800.1 - 1.5e-27 96.2 0.0 6.1e-27 94.3 0.0 2.2 1 0 0 1 1 1 1 Holliday-junction resolvase-like of SPT6 SPT6_acidic PF14632.6 KFX87800.1 - 4.3e-19 68.9 19.8 4.3e-19 68.9 19.8 5.7 4 1 3 7 7 7 1 Acidic N-terminal SPT6 HHH_9 PF17674.1 KFX87800.1 - 2.2e-05 25.3 2.4 0.00073 20.4 2.4 3.4 1 1 0 1 1 1 1 HHH domain SH2 PF00017.24 KFX87800.1 - 7.9e-05 22.7 0.0 0.00024 21.2 0.0 1.9 1 0 0 1 1 1 1 SH2 domain Tex_YqgF PF16921.5 KFX87800.1 - 0.023 15.1 0.0 0.15 12.5 0.0 2.2 1 1 0 1 1 1 0 Tex protein YqgF-like domain HHH_3 PF12836.7 KFX87800.1 - 0.033 14.4 0.0 0.099 12.9 0.0 1.9 1 0 0 1 1 1 0 Helix-hairpin-helix motif Pkinase PF00069.25 KFX87801.1 - 4.1e-16 59.1 0.5 4.9e-16 58.9 0.5 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFX87801.1 - 1.2e-08 34.6 0.4 1.4e-08 34.3 0.4 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase BING4CT PF08149.11 KFX87818.1 - 1.1e-40 137.3 0.0 8.4e-36 121.6 0.0 3.4 3 0 0 3 3 3 2 BING4CT (NUC141) domain WD40 PF00400.32 KFX87818.1 - 1.8e-05 25.4 0.0 0.06 14.2 0.0 3.6 4 0 0 4 4 4 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFX87818.1 - 2.6e-05 24.4 0.0 4 7.8 0.0 4.1 2 1 1 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain SNAP PF14938.6 KFX87819.1 - 2.5e-112 374.9 13.5 2.8e-112 374.7 13.5 1.0 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP TPR_12 PF13424.6 KFX87819.1 - 3e-07 30.6 6.6 0.13 12.6 0.2 3.7 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_7 PF13176.6 KFX87819.1 - 1.2e-06 28.1 4.6 0.034 14.2 0.3 5.3 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_8 PF13181.6 KFX87819.1 - 0.00051 20.1 11.6 0.047 13.9 0.4 4.5 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_1 PF00515.28 KFX87819.1 - 0.0036 17.1 8.2 3.3 7.7 0.1 5.1 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.17 KFX87819.1 - 0.006 16.6 9.6 3.1 8.2 0.1 5.4 2 1 4 6 6 6 2 Tetratricopeptide repeat DUF2521 PF10730.9 KFX87819.1 - 0.018 15.0 0.7 0.048 13.7 0.1 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF2521) TPR_6 PF13174.6 KFX87819.1 - 0.51 11.1 11.6 13 6.7 0.1 5.4 5 1 1 6 6 6 0 Tetratricopeptide repeat Glu-tRNAGln PF02686.15 KFX87820.1 - 5.8e-11 42.5 1.5 1.8e-10 40.9 1.5 1.7 1 1 0 1 1 1 1 Glu-tRNAGln amidotransferase C subunit DUF241 PF03087.14 KFX87820.1 - 0.09 12.6 0.2 0.13 12.1 0.2 1.1 1 0 0 1 1 1 0 Arabidopsis protein of unknown function DUF726 PF05277.12 KFX87821.1 - 8.8e-131 435.9 3.4 1.2e-130 435.5 3.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF726) Thioesterase PF00975.20 KFX87821.1 - 0.0057 16.8 0.0 0.018 15.1 0.0 1.8 1 0 0 1 1 1 1 Thioesterase domain PE-PPE PF08237.11 KFX87821.1 - 0.017 14.7 0.0 0.036 13.6 0.0 1.5 1 0 0 1 1 1 0 PE-PPE domain Abhydrolase_6 PF12697.7 KFX87821.1 - 0.29 11.7 2.9 0.51 10.9 0.0 2.2 2 0 0 2 2 2 0 Alpha/beta hydrolase family DUF2514 PF10721.9 KFX87822.1 - 0.36 10.8 7.1 0.5 10.4 7.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2514) DMAP1_like PF17024.5 KFX87828.1 - 0.12 12.6 0.0 0.17 12.0 0.0 1.2 1 0 0 1 1 1 0 Putative DMAP1-like INO80_Ies4 PF08193.11 KFX87829.1 - 6e-64 216.3 19.2 7.2e-64 216.1 19.2 1.1 1 0 0 1 1 1 1 INO80 complex subunit Ies4 Utp12 PF04003.12 KFX87831.1 - 2.7e-25 88.7 0.1 3.6e-25 88.4 0.1 1.2 1 0 0 1 1 1 1 Dip2/Utp12 Family Peptidase_C74 PF12387.8 KFX87831.1 - 0.19 11.2 0.0 0.29 10.6 0.0 1.2 1 0 0 1 1 1 0 Pestivirus NS2 peptidase SURF2 PF05477.11 KFX87831.1 - 0.53 9.9 10.4 0.81 9.3 10.4 1.3 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) BUD22 PF09073.10 KFX87831.1 - 0.61 9.4 23.3 0.95 8.7 23.3 1.2 1 0 0 1 1 1 0 BUD22 Speriolin_N PF15058.6 KFX87831.1 - 2.7 8.0 7.9 11 6.0 2.4 2.3 2 0 0 2 2 2 0 Speriolin N terminus SDA1 PF05285.12 KFX87831.1 - 5.9 6.2 28.9 7.9 5.8 28.9 1.1 1 0 0 1 1 1 0 SDA1 HLH PF00010.26 KFX87832.1 - 2.5e-07 30.5 0.0 5.7e-07 29.4 0.0 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Adaptin_N PF01602.20 KFX87834.1 - 1.8e-122 409.6 5.8 2.2e-122 409.3 5.8 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptin_C PF02296.16 KFX87834.1 - 3.1e-45 153.0 0.0 7.5e-45 151.8 0.0 1.7 1 0 0 1 1 1 1 Alpha adaptin AP2, C-terminal domain Alpha_adaptinC2 PF02883.20 KFX87834.1 - 2.8e-18 66.2 0.0 5.6e-18 65.3 0.0 1.5 1 0 0 1 1 1 1 Adaptin C-terminal domain Cnd1 PF12717.7 KFX87834.1 - 0.0016 18.5 0.2 0.16 12.0 0.0 2.7 1 1 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 RTP1_C1 PF10363.9 KFX87834.1 - 0.13 12.4 0.3 1.1 9.5 0.1 2.5 2 0 0 2 2 2 0 Required for nuclear transport of RNA pol II C-terminus 1 ACTH_assoc PF16102.5 KFX87835.1 - 0.079 13.8 3.5 9.4 7.3 0.1 3.9 3 0 0 3 3 3 0 ACTH-associated domain MARVEL PF01284.23 KFX87836.1 - 1e-26 93.7 14.4 1.3e-26 93.4 14.4 1.1 1 0 0 1 1 1 1 Membrane-associating domain MpPF26 PF07666.11 KFX87836.1 - 0.022 14.9 3.8 0.23 11.6 2.7 2.6 2 1 1 3 3 3 0 M penetrans paralogue family 26 MTABC_N PF16185.5 KFX87836.1 - 0.18 11.3 6.0 0.26 10.8 5.6 1.6 1 1 0 1 1 1 0 Mitochondrial ABC-transporter N-terminal five TM region CSTF_C PF14304.6 KFX87837.1 - 0.012 15.2 0.6 0.044 13.4 0.6 1.9 1 1 0 1 1 1 0 Transcription termination and cleavage factor C-terminal TMF_TATA_bd PF12325.8 KFX87837.1 - 0.032 14.5 0.4 0.036 14.3 0.4 1.1 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding Fis1_TPR_C PF14853.6 KFX87837.1 - 0.089 12.9 0.3 0.11 12.5 0.3 1.2 1 0 0 1 1 1 0 Fis1 C-terminal tetratricopeptide repeat PAP1 PF08601.10 KFX87838.1 - 5.3e-115 385.1 22.4 5.3e-115 385.1 22.4 2.2 2 0 0 2 2 2 1 Transcription factor PAP1 bZIP_1 PF00170.21 KFX87838.1 - 3.5e-07 30.2 10.8 7.7e-07 29.1 10.8 1.5 1 0 0 1 1 1 1 bZIP transcription factor Nop53 PF07767.11 KFX87838.1 - 0.0038 16.7 11.9 0.0062 16.0 11.9 1.2 1 0 0 1 1 1 1 Nop53 (60S ribosomal biogenesis) NAM-associated PF14303.6 KFX87838.1 - 0.0059 17.4 6.6 0.0059 17.4 6.6 3.3 3 1 0 3 3 3 1 No apical meristem-associated C-terminal domain bZIP_2 PF07716.15 KFX87838.1 - 0.0096 16.0 10.9 0.025 14.6 10.9 1.7 1 1 0 1 1 1 1 Basic region leucine zipper CCDC158 PF15921.5 KFX87838.1 - 0.019 12.8 1.1 0.031 12.1 1.1 1.2 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 158 SHE3 PF17078.5 KFX87838.1 - 0.031 14.0 3.8 0.053 13.2 3.8 1.3 1 0 0 1 1 1 0 SWI5-dependent HO expression protein 3 DUF812 PF05667.11 KFX87838.1 - 0.079 11.8 5.2 0.13 11.1 5.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF812) DUF4635 PF15466.6 KFX87838.1 - 0.17 11.4 0.7 0.36 10.4 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4635) TolA_bind_tri PF16331.5 KFX87838.1 - 0.25 11.5 2.7 3 8.0 0.2 2.5 2 0 0 2 2 2 0 TolA binding protein trimerisation bZIP_Maf PF03131.17 KFX87838.1 - 0.44 11.1 7.7 0.96 10.0 7.7 1.5 1 0 0 1 1 1 0 bZIP Maf transcription factor TMCO5 PF14992.6 KFX87838.1 - 0.44 10.1 3.2 0.71 9.4 3.2 1.2 1 0 0 1 1 1 0 TMCO5 family CDC45 PF02724.14 KFX87838.1 - 1.2 7.3 8.5 1.8 6.8 8.5 1.1 1 0 0 1 1 1 0 CDC45-like protein Pkinase PF00069.25 KFX87852.1 - 4.6e-24 85.2 0.0 4.1e-14 52.6 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KFX87852.1 - 2.8e-08 33.4 0.0 1.4e-07 31.1 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KFX87852.1 - 0.00024 21.1 0.1 0.00062 19.8 0.1 1.7 1 1 0 1 1 1 1 Phosphotransferase enzyme family Ank_2 PF12796.7 KFX87853.1 - 2.9e-17 63.0 0.0 1.4e-05 25.6 0.1 4.9 2 2 3 5 5 5 4 Ankyrin repeats (3 copies) SesA PF17107.5 KFX87853.1 - 5.1e-16 59.0 0.1 1.3e-15 57.7 0.1 1.7 1 0 0 1 1 1 1 N-terminal domain on NACHT_NTPase and P-loop NTPases Ank_5 PF13857.6 KFX87853.1 - 2.2e-13 50.2 3.1 0.00012 22.3 0.0 6.2 6 0 0 6 6 6 3 Ankyrin repeats (many copies) Ank_4 PF13637.6 KFX87853.1 - 7.1e-10 39.2 3.2 0.53 10.9 0.0 6.5 4 1 2 6 6 6 3 Ankyrin repeats (many copies) Ank PF00023.30 KFX87853.1 - 8.3e-10 38.7 3.2 0.15 12.6 0.1 7.1 7 0 0 7 7 7 3 Ankyrin repeat Helo_like_N PF17111.5 KFX87853.1 - 0.00022 20.7 0.2 0.00046 19.6 0.2 1.5 1 0 0 1 1 1 1 Fungal N-terminal domain of STAND proteins AA_permease PF00324.21 KFX87854.1 - 1.6e-139 465.6 38.6 2e-139 465.3 38.6 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KFX87854.1 - 4.9e-34 117.9 41.4 6.4e-34 117.5 41.4 1.2 1 0 0 1 1 1 1 Amino acid permease PDH PF02153.17 KFX87856.1 - 6.4e-14 51.6 0.0 1.1e-13 50.8 0.0 1.3 1 0 0 1 1 1 1 Prephenate dehydrogenase NAD_binding_2 PF03446.15 KFX87856.1 - 6.1e-07 29.7 0.0 2.8e-06 27.6 0.0 2.1 2 1 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.17 KFX87856.1 - 5e-05 23.8 0.0 9.4e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent 3HCDH_N PF02737.18 KFX87856.1 - 0.00079 19.4 0.0 0.0016 18.3 0.0 1.5 1 1 1 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.19 KFX87856.1 - 0.0016 17.8 0.0 0.0031 16.9 0.0 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ApbA PF02558.16 KFX87856.1 - 0.0021 17.7 0.0 0.0037 16.9 0.0 1.5 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Shikimate_DH PF01488.20 KFX87856.1 - 0.0029 17.7 0.0 0.22 11.6 0.0 2.3 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase TrkA_N PF02254.18 KFX87856.1 - 0.04 14.2 0.0 0.095 13.0 0.0 1.6 1 0 0 1 1 1 0 TrkA-N domain EccE PF11203.8 KFX87856.1 - 0.045 14.1 0.1 2 8.8 0.1 2.3 2 0 0 2 2 2 0 Putative type VII ESX secretion system translocon, EccE XdhC_C PF13478.6 KFX87856.1 - 0.045 14.2 0.0 0.1 13.1 0.0 1.8 1 1 0 1 1 1 0 XdhC Rossmann domain Pyr_redox PF00070.27 KFX87856.1 - 0.19 12.3 0.0 0.61 10.7 0.0 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Ribosomal_S11 PF00411.19 KFX87857.1 - 4e-46 155.9 1.3 4.9e-46 155.7 1.3 1.1 1 0 0 1 1 1 1 Ribosomal protein S11 CBM_25 PF03423.13 KFX87857.1 - 0.064 13.5 0.0 0.12 12.6 0.0 1.5 1 0 0 1 1 1 0 Carbohydrate binding domain (family 25) AAR2 PF05282.11 KFX87858.1 - 2.8e-66 224.3 0.0 3.6e-66 224.0 0.0 1.1 1 0 0 1 1 1 1 AAR2 protein HisKA_3 PF07730.13 KFX87859.1 - 0.0066 16.9 0.8 2.7 8.6 0.2 2.2 1 1 1 2 2 2 2 Histidine kinase UPF0242 PF06785.11 KFX87859.1 - 0.011 15.9 2.1 0.015 15.4 1.7 1.4 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Mce4_CUP1 PF11887.8 KFX87859.1 - 0.032 13.7 0.2 0.041 13.3 0.2 1.1 1 0 0 1 1 1 0 Cholesterol uptake porter CUP1 of Mce4, putative Sec2p PF06428.11 KFX87859.1 - 0.049 13.6 0.6 0.049 13.6 0.6 1.8 2 0 0 2 2 2 0 GDP/GTP exchange factor Sec2p DUF2564 PF10819.8 KFX87859.1 - 0.054 13.9 1.8 0.13 12.7 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2564) Ribosomal_S9 PF00380.19 KFX87860.1 - 2.9e-34 118.2 0.1 3.3e-34 118.0 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S9/S16 WSC PF01822.19 KFX87861.1 - 2e-68 226.6 67.2 5.2e-19 68.2 10.4 4.4 4 0 0 4 4 4 4 WSC domain Glyoxal_oxid_N PF07250.11 KFX87861.1 - 1.8e-30 105.9 0.0 1.6e-29 102.8 0.0 2.3 2 1 1 3 3 3 1 Glyoxal oxidase N-terminus DUF1929 PF09118.11 KFX87861.1 - 7.9e-24 83.8 0.7 1.1e-22 80.2 0.1 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF1929) Kelch_6 PF13964.6 KFX87861.1 - 0.13 12.5 1.3 1.5 9.2 0.0 3.5 3 0 0 3 3 3 0 Kelch motif Kelch_2 PF07646.15 KFX87861.1 - 0.5 10.4 2.2 2.5 8.2 0.1 3.2 3 0 0 3 3 3 0 Kelch motif DUF3402 PF11882.8 KFX87866.1 - 2e-188 627.2 0.0 2.7e-188 626.8 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3402) N1221 PF07923.13 KFX87866.1 - 1e-81 274.3 0.0 1.4e-81 273.9 0.0 1.2 1 0 0 1 1 1 1 N1221-like protein QCR10 PF09796.9 KFX87869.1 - 2e-28 98.3 0.8 2.5e-28 97.9 0.8 1.1 1 0 0 1 1 1 1 Ubiquinol-cytochrome-c reductase complex subunit (QCR10) Glyco_transf_90 PF05686.12 KFX87873.1 - 9.2e-19 67.6 0.0 7.2e-15 54.8 0.0 2.0 2 0 0 2 2 2 2 Glycosyl transferase family 90 Glyco_trans_1_2 PF13524.6 KFX87873.1 - 0.032 14.6 0.0 0.057 13.8 0.0 1.5 1 1 0 1 1 1 0 Glycosyl transferases group 1 Peptidase_M22 PF00814.25 KFX87875.1 - 3.7e-15 56.4 0.0 4.2e-15 56.2 0.0 1.0 1 0 0 1 1 1 1 Glycoprotease family Porin_3 PF01459.22 KFX87878.1 - 2.5e-86 289.5 0.5 2.8e-86 289.3 0.5 1.0 1 0 0 1 1 1 1 Eukaryotic porin Aminotran_4 PF01063.19 KFX87878.1 - 0.19 11.6 0.0 1.3 8.8 0.0 2.0 2 0 0 2 2 2 0 Amino-transferase class IV 6PF2K PF01591.18 KFX87879.1 - 6.2e-57 192.5 0.0 8.7e-57 192.0 0.0 1.2 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.22 KFX87879.1 - 7.1e-22 78.0 0.1 2.2e-21 76.4 0.1 1.8 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) IstB_IS21 PF01695.17 KFX87879.1 - 0.045 13.5 0.0 0.092 12.5 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_33 PF13671.6 KFX87879.1 - 0.11 12.6 0.0 0.27 11.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain APS_kinase PF01583.20 KFX87879.1 - 0.16 11.9 0.0 1.3 8.9 0.0 2.1 1 1 0 1 1 1 0 Adenylylsulphate kinase MIF4G_like PF09088.11 KFX87880.1 - 6.1e-91 303.4 0.1 9e-91 302.8 0.1 1.3 1 0 0 1 1 1 1 MIF4G like MIF4G_like_2 PF09090.11 KFX87880.1 - 4.7e-73 245.9 0.0 6.9e-73 245.4 0.0 1.3 1 0 0 1 1 1 1 MIF4G like MIF4G PF02854.19 KFX87880.1 - 0.025 14.2 0.0 0.093 12.4 0.0 1.9 2 0 0 2 2 2 0 MIF4G domain Ribosomal_L5_C PF00673.21 KFX87881.1 - 5.2e-27 93.9 0.0 8.8e-27 93.1 0.0 1.4 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.19 KFX87881.1 - 1.8e-15 57.0 0.1 3.5e-15 56.1 0.1 1.5 1 0 0 1 1 1 1 Ribosomal protein L5 Fes1 PF08609.10 KFX87882.1 - 1e-09 39.2 2.9 1e-09 39.2 2.9 2.0 2 1 0 2 2 2 1 Nucleotide exchange factor Fes1 Arm PF00514.23 KFX87882.1 - 5.2e-08 32.7 0.1 0.0062 16.5 0.0 2.9 3 1 0 3 3 3 2 Armadillo/beta-catenin-like repeat HEAT PF02985.22 KFX87882.1 - 3.1e-06 27.0 0.0 0.01 16.0 0.0 3.5 3 0 0 3 3 3 1 HEAT repeat HEAT_EZ PF13513.6 KFX87882.1 - 4.4e-06 27.1 0.2 0.00069 20.1 0.0 2.3 1 1 1 2 2 2 2 HEAT-like repeat HEAT_2 PF13646.6 KFX87882.1 - 4.6e-06 26.9 0.0 1.9e-05 24.9 0.0 2.0 2 1 0 2 2 2 1 HEAT repeats DUF3535 PF12054.8 KFX87882.1 - 0.012 14.9 0.0 0.014 14.6 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3535) V-ATPase_H_C PF11698.8 KFX87882.1 - 0.043 13.9 0.0 0.099 12.8 0.0 1.6 1 1 0 1 1 1 0 V-ATPase subunit H Atx10homo_assoc PF09759.9 KFX87882.1 - 0.048 13.7 0.0 0.081 13.0 0.0 1.4 1 0 0 1 1 1 0 Spinocerebellar ataxia type 10 protein domain Adaptin_N PF01602.20 KFX87882.1 - 0.062 11.8 0.1 5.1 5.5 0.0 2.0 2 0 0 2 2 2 0 Adaptin N terminal region Uso1_p115_head PF04869.14 KFX87882.1 - 0.1 11.7 0.4 3.7 6.6 0.1 2.6 1 1 2 3 3 3 0 Uso1 / p115 like vesicle tethering protein, head region ATP-grasp_4 PF13535.6 KFX87882.1 - 0.11 12.1 0.0 0.16 11.5 0.0 1.2 1 0 0 1 1 1 0 ATP-grasp domain DUF825 PF05695.12 KFX87882.1 - 0.14 9.3 0.0 0.17 9.0 0.0 1.0 1 0 0 1 1 1 0 Plant protein of unknown function (DUF825) S1 PF00575.23 KFX87887.1 - 0.014 15.7 0.1 5.7 7.4 0.0 2.6 2 0 0 2 2 2 0 S1 RNA binding domain DOT1 PF08123.13 KFX87888.1 - 5e-72 241.7 0.1 7.3e-72 241.2 0.1 1.3 1 0 0 1 1 1 1 Histone methylation protein DOT1 ATG16 PF08614.11 KFX87889.1 - 2.3e-51 174.9 14.9 3.3e-51 174.4 14.9 1.2 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) UPF0242 PF06785.11 KFX87889.1 - 0.12 12.4 11.2 1.1 9.3 11.2 2.4 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus bZIP_1 PF00170.21 KFX87889.1 - 0.58 10.3 0.1 0.58 10.3 0.1 3.1 2 1 0 3 3 3 0 bZIP transcription factor APG6_N PF17675.1 KFX87889.1 - 4.2 7.9 18.5 2.7e+03 -1.2 18.7 2.9 1 1 0 1 1 1 0 Apg6 coiled-coil region DHR10 PF18595.1 KFX87889.1 - 5.1 7.2 20.5 0.65 10.1 1.7 3.0 2 1 1 3 3 3 0 Designed helical repeat protein 10 domain Ras PF00071.22 KFX87890.1 - 1.4e-56 190.5 0.1 1.7e-56 190.3 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFX87890.1 - 6.2e-32 110.3 0.0 8.7e-32 109.9 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFX87890.1 - 9.9e-13 47.9 0.0 1.2e-12 47.7 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 KFX87890.1 - 9.1e-08 32.2 0.0 1.5e-07 31.5 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 KFX87890.1 - 2.1e-06 27.2 0.0 2.7e-06 26.9 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 KFX87890.1 - 1.2e-05 24.9 0.0 0.00058 19.4 0.0 2.2 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 KFX87890.1 - 7.3e-05 22.7 0.1 0.0048 16.8 0.1 2.4 1 1 2 3 3 3 1 RsgA GTPase PduV-EutP PF10662.9 KFX87890.1 - 0.0035 17.1 0.1 0.12 12.2 0.0 2.2 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation cobW PF02492.19 KFX87890.1 - 0.0065 16.1 0.0 0.029 14.0 0.0 1.9 1 1 1 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain ATP_bind_1 PF03029.17 KFX87890.1 - 0.007 16.2 0.3 0.19 11.5 0.0 2.1 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein AAA_5 PF07728.14 KFX87890.1 - 0.0074 16.3 0.0 0.014 15.4 0.0 1.7 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 KFX87890.1 - 0.01 16.1 0.0 0.016 15.5 0.0 1.4 1 1 0 1 1 1 1 AAA domain SRPRB PF09439.10 KFX87890.1 - 0.01 15.3 0.0 0.012 15.0 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit Septin PF00735.18 KFX87890.1 - 0.01 15.1 0.1 0.047 13.0 0.0 2.0 2 0 0 2 2 2 0 Septin AAA_16 PF13191.6 KFX87890.1 - 0.016 15.6 0.0 0.021 15.2 0.0 1.6 1 1 0 1 1 1 0 AAA ATPase domain AAA_24 PF13479.6 KFX87890.1 - 0.022 14.5 0.0 0.037 13.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 KFX87890.1 - 0.026 14.0 0.1 0.047 13.2 0.1 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region Glyco_hydro_75 PF07335.11 KFX87890.1 - 0.073 13.3 0.0 0.11 12.8 0.0 1.4 1 0 0 1 1 1 0 Fungal chitosanase of glycosyl hydrolase group 75 ATPase_2 PF01637.18 KFX87890.1 - 0.08 12.8 0.5 0.14 12.1 0.1 1.5 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea TniB PF05621.11 KFX87890.1 - 0.12 11.8 0.0 0.18 11.2 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein NACHT PF05729.12 KFX87890.1 - 0.12 12.2 0.0 0.19 11.6 0.0 1.3 1 0 0 1 1 1 0 NACHT domain NTPase_1 PF03266.15 KFX87890.1 - 0.15 12.0 0.0 0.23 11.4 0.0 1.4 1 0 0 1 1 1 0 NTPase FeoB_N PF02421.18 KFX87890.1 - 0.16 11.5 0.0 1.6 8.2 0.0 2.1 2 0 0 2 2 2 0 Ferrous iron transport protein B NB-ARC PF00931.22 KFX87890.1 - 0.16 11.1 0.1 0.31 10.2 0.0 1.5 2 0 0 2 2 2 0 NB-ARC domain DUF3955 PF13127.6 KFX87891.1 - 7.8e-10 38.4 2.8 5.9e-09 35.6 2.1 2.8 2 0 0 2 2 2 1 Protein of unknown function (DUF3955) EamA PF00892.20 KFX87891.1 - 1.6e-09 38.1 41.6 3e-06 27.5 9.3 3.1 3 0 0 3 3 3 3 EamA-like transporter family SLC35F PF06027.12 KFX87891.1 - 1.2e-07 31.6 14.9 2.4e-07 30.6 11.9 2.6 2 1 0 2 2 2 1 Solute carrier family 35 PUNUT PF16913.5 KFX87891.1 - 1.2e-05 24.7 3.5 1.2e-05 24.7 3.5 2.6 3 0 0 3 3 3 1 Purine nucleobase transmembrane transport Spb1_C PF07780.12 KFX87892.1 - 1.9e-85 285.8 8.5 1.9e-85 285.8 8.5 3.1 4 0 0 4 4 4 1 Spb1 C-terminal domain FtsJ PF01728.19 KFX87892.1 - 1e-55 188.6 0.1 2e-55 187.7 0.1 1.5 1 0 0 1 1 1 1 FtsJ-like methyltransferase DUF3381 PF11861.8 KFX87892.1 - 1.2e-50 171.5 6.8 1.2e-50 171.5 6.8 4.3 4 0 0 4 4 4 1 Domain of unknown function (DUF3381) Methyltransf_23 PF13489.6 KFX87892.1 - 0.018 14.9 0.0 0.044 13.6 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Methyltr_RsmB-F PF01189.17 KFX87892.1 - 0.061 13.0 0.0 0.15 11.7 0.0 1.6 1 0 0 1 1 1 0 16S rRNA methyltransferase RsmB/F DUF3915 PF13054.6 KFX87892.1 - 0.1 12.6 0.4 0.34 10.9 0.4 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3915) DUF4519 PF15012.6 KFX87892.1 - 3.8 7.7 7.7 16 5.8 7.7 2.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4519) WD40 PF00400.32 KFX87893.1 - 1.8e-10 41.2 6.3 0.047 14.6 0.0 5.9 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFX87893.1 - 1e-06 29.0 0.1 0.013 15.7 0.0 4.9 4 1 1 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain Met_asp_mut_E PF06368.11 KFX87893.1 - 0.041 12.4 0.0 0.064 11.7 0.0 1.2 1 0 0 1 1 1 0 Methylaspartate mutase E chain (MutE) Ge1_WD40 PF16529.5 KFX87893.1 - 0.11 11.4 0.1 6.6 5.6 0.1 2.6 2 1 1 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 KFX87893.1 - 0.16 10.6 0.7 0.94 8.0 0.5 2.1 1 1 1 2 2 2 0 Nucleoporin Nup120/160 DUF3328 PF11807.8 KFX87895.1 - 4.7e-11 42.9 0.5 4.7e-11 42.9 0.5 1.9 1 1 1 2 2 2 1 Domain of unknown function (DUF3328) Cyclin_N PF00134.23 KFX87901.1 - 1.9e-43 147.2 0.0 3.3e-43 146.5 0.0 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 KFX87901.1 - 7.4e-37 126.1 0.0 2.2e-36 124.5 0.0 1.9 1 0 0 1 1 1 1 Cyclin, C-terminal domain Mito_carr PF00153.27 KFX87902.1 - 3.7e-73 241.5 0.7 1.6e-25 88.8 0.0 3.4 2 1 1 3 3 3 3 Mitochondrial carrier protein EF-hand_7 PF13499.6 KFX87902.1 - 4.8e-18 65.4 4.4 6.7e-09 36.1 0.6 3.8 3 1 1 4 4 4 3 EF-hand domain pair EF-hand_1 PF00036.32 KFX87902.1 - 2.6e-15 54.8 6.7 1e-06 27.8 0.2 5.9 6 0 0 6 6 6 3 EF hand EF-hand_6 PF13405.6 KFX87902.1 - 1e-14 53.1 4.8 1.8e-06 27.4 0.2 6.2 6 0 0 6 6 6 3 EF-hand domain EF-hand_8 PF13833.6 KFX87902.1 - 5e-10 39.1 4.8 0.19 11.6 0.0 5.9 5 2 2 7 7 7 3 EF-hand domain pair EF-hand_5 PF13202.6 KFX87902.1 - 4.6e-09 35.4 3.8 3.6e-05 23.1 0.3 4.4 4 0 0 4 4 4 1 EF hand Dockerin_1 PF00404.18 KFX87902.1 - 0.02 15.1 0.2 3.3 8.0 0.1 3.2 2 1 1 3 3 3 0 Dockerin type I domain p25-alpha PF05517.12 KFX87902.1 - 0.16 12.1 0.6 13 6.0 0.3 3.1 1 1 1 2 2 2 0 p25-alpha Chitin_synth_1 PF01644.17 KFX87906.1 - 2.4e-75 252.0 0.1 3.5e-75 251.4 0.1 1.3 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.11 KFX87906.1 - 1.1e-28 99.0 0.0 2.5e-28 97.8 0.0 1.7 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.15 KFX87906.1 - 1.9e-20 73.0 7.4 7.3e-17 61.2 0.0 2.3 2 0 0 2 2 2 2 Chitin synthase Glyco_tranf_2_3 PF13641.6 KFX87906.1 - 0.0059 16.5 0.0 0.012 15.6 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase like family 2 RNA_pol_L_2 PF13656.6 KFX87908.1 - 5.2e-34 115.9 0.0 6.9e-34 115.5 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.24 KFX87908.1 - 2.4e-12 46.1 0.0 3.6e-12 45.5 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Complex1_LYR_2 PF13233.6 KFX87909.1 - 5e-05 24.0 0.7 8.2e-05 23.3 0.7 1.4 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.15 KFX87909.1 - 0.0043 17.1 0.1 0.011 15.8 0.1 1.8 1 1 0 1 1 1 1 Complex 1 protein (LYR family) R-HINP1I PF11463.8 KFX87909.1 - 0.026 14.0 0.5 0.35 10.3 0.0 2.0 2 0 0 2 2 2 0 R.HinP1I restriction endonuclease TMIE PF16038.5 KFX87909.1 - 0.11 12.4 0.1 0.22 11.4 0.1 1.5 1 1 1 2 2 2 0 TMIE protein G10 PF01125.17 KFX87910.1 - 1.8e-59 199.7 6.6 2e-59 199.6 6.6 1.0 1 0 0 1 1 1 1 G10 protein DUF2207 PF09972.9 KFX87913.1 - 0.0074 15.1 0.1 0.0096 14.7 0.1 1.0 1 0 0 1 1 1 1 Predicted membrane protein (DUF2207) DUF2304 PF10066.9 KFX87913.1 - 0.01 16.1 0.4 0.017 15.3 0.3 1.4 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2304) AIF-MLS PF14962.6 KFX87913.1 - 0.05 13.6 0.2 0.086 12.8 0.2 1.3 1 0 0 1 1 1 0 Mitochondria Localisation Sequence Glyco_hydro_76 PF03663.14 KFX87915.1 - 3e-140 467.9 13.4 3.5e-140 467.7 13.4 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Glyco_hydro_88 PF07470.13 KFX87915.1 - 0.88 8.6 9.9 0.34 9.9 1.1 2.9 2 1 1 3 3 3 0 Glycosyl Hydrolase Family 88 ORC4_C PF14629.6 KFX87916.1 - 1.1e-65 221.1 0.0 2e-65 220.2 0.0 1.5 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 4 C-terminus AAA_16 PF13191.6 KFX87916.1 - 4.3e-16 59.8 0.4 1.1e-15 58.4 0.4 1.7 1 0 0 1 1 1 1 AAA ATPase domain PHD_2 PF13831.6 KFX87916.1 - 3.8e-11 42.3 2.3 8e-11 41.3 2.3 1.6 1 0 0 1 1 1 1 PHD-finger PHD PF00628.29 KFX87916.1 - 1.5e-10 40.8 6.8 2.5e-10 40.1 6.8 1.4 1 0 0 1 1 1 1 PHD-finger AAA_22 PF13401.6 KFX87916.1 - 1.6e-09 38.1 0.0 3.1e-09 37.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain NACHT PF05729.12 KFX87916.1 - 1.2e-07 31.8 0.1 5.2e-07 29.7 0.1 1.9 1 1 0 1 1 1 1 NACHT domain AAA PF00004.29 KFX87916.1 - 1.5e-07 31.9 0.0 4.6e-07 30.3 0.0 1.8 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ATPase_2 PF01637.18 KFX87916.1 - 5.4e-05 23.2 0.0 8.8e-05 22.5 0.0 1.2 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea NB-ARC PF00931.22 KFX87916.1 - 7.3e-05 22.1 0.1 0.00012 21.4 0.1 1.2 1 0 0 1 1 1 1 NB-ARC domain KAP_NTPase PF07693.14 KFX87916.1 - 0.00028 20.2 0.0 0.00044 19.6 0.0 1.2 1 0 0 1 1 1 1 KAP family P-loop domain AAA_19 PF13245.6 KFX87916.1 - 0.0003 21.1 0.0 0.0006 20.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.6 KFX87916.1 - 0.00034 20.7 0.0 0.00094 19.2 0.0 1.8 1 1 0 1 1 1 1 AAA domain TniB PF05621.11 KFX87916.1 - 0.0004 19.9 0.0 0.029 13.8 0.0 2.2 1 1 0 1 1 1 1 Bacterial TniB protein DUF815 PF05673.13 KFX87916.1 - 0.00065 18.9 0.0 0.0012 18.1 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) ATP_bind_1 PF03029.17 KFX87916.1 - 0.0012 18.7 0.0 0.15 11.8 0.0 2.5 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein C1_1 PF00130.22 KFX87916.1 - 0.002 17.9 0.9 0.002 17.9 0.9 1.6 1 1 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) AAA_30 PF13604.6 KFX87916.1 - 0.0021 17.8 0.1 0.004 16.9 0.1 1.4 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 KFX87916.1 - 0.0044 17.2 0.3 0.037 14.2 0.2 2.5 2 1 0 2 2 2 1 AAA domain AAA_29 PF13555.6 KFX87916.1 - 0.0055 16.4 0.0 0.012 15.3 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain FtsK_SpoIIIE PF01580.18 KFX87916.1 - 0.026 13.9 0.0 0.052 12.9 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family NTPase_1 PF03266.15 KFX87916.1 - 0.026 14.4 0.0 0.2 11.5 0.0 2.2 2 0 0 2 2 2 0 NTPase MobB PF03205.14 KFX87916.1 - 0.028 14.3 0.0 0.055 13.4 0.0 1.4 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B T2SSE PF00437.20 KFX87916.1 - 0.03 13.4 0.0 0.05 12.7 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein PIF1 PF05970.14 KFX87916.1 - 0.038 13.2 0.0 0.076 12.2 0.0 1.4 2 0 0 2 2 1 0 PIF1-like helicase FYVE_2 PF02318.16 KFX87916.1 - 0.041 14.1 1.1 0.091 13.0 1.1 1.5 1 0 0 1 1 1 0 FYVE-type zinc finger AAA_18 PF13238.6 KFX87916.1 - 0.049 14.2 0.0 0.095 13.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 KFX87916.1 - 0.051 13.1 0.0 0.091 12.3 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_5 PF07728.14 KFX87916.1 - 0.068 13.2 0.0 0.14 12.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) cobW PF02492.19 KFX87916.1 - 0.076 12.6 0.0 0.17 11.5 0.0 1.6 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain Prok-RING_1 PF14446.6 KFX87916.1 - 0.081 12.9 3.1 0.17 11.9 3.1 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 ABC_tran PF00005.27 KFX87916.1 - 0.085 13.4 0.0 0.17 12.4 0.0 1.5 1 0 0 1 1 1 0 ABC transporter SRP54 PF00448.22 KFX87916.1 - 0.089 12.4 0.0 0.69 9.5 0.0 2.1 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain C1_2 PF03107.16 KFX87916.1 - 0.11 12.8 1.7 0.26 11.6 1.7 1.6 1 0 0 1 1 1 0 C1 domain GTP_EFTU PF00009.27 KFX87916.1 - 0.16 11.5 0.1 1.9 8.0 0.1 2.4 3 0 0 3 3 3 0 Elongation factor Tu GTP binding domain PduV-EutP PF10662.9 KFX87916.1 - 0.21 11.3 0.1 4.3 7.1 0.0 2.4 2 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Zf_RING PF16744.5 KFX87916.1 - 0.79 9.9 4.8 1.7 8.8 4.8 1.6 1 0 0 1 1 1 0 KIAA1045 RING finger zf-piccolo PF05715.13 KFX87916.1 - 1.2 9.3 6.0 3 8.0 6.0 1.7 1 0 0 1 1 1 0 Piccolo Zn-finger zf-RING_9 PF13901.6 KFX87916.1 - 1.7 8.6 3.9 2.9 7.8 3.9 1.3 1 0 0 1 1 1 0 Putative zinc-RING and/or ribbon DLIC PF05783.11 KFX87916.1 - 3.7 6.3 7.2 0.74 8.6 0.1 2.6 2 1 1 3 3 3 0 Dynein light intermediate chain (DLIC) AT_hook PF02178.19 KFX87916.1 - 7 6.9 46.7 0.16 11.9 3.8 4.9 5 0 0 5 5 3 0 AT hook motif CUE PF02845.16 KFX87918.1 - 2.5e-12 46.2 0.0 3.8e-12 45.7 0.0 1.3 1 0 0 1 1 1 1 CUE domain G2BR PF18442.1 KFX87918.1 - 0.13 11.9 7.9 0.26 10.9 7.9 1.4 1 0 0 1 1 1 0 E3 gp78 Ube2g2-binding region (G2BR) Cue1_U7BR PF18499.1 KFX87918.1 - 0.23 11.5 2.0 0.4 10.8 2.0 1.3 1 0 0 1 1 1 0 Ubc7p-binding region of Cue1 Kelch_4 PF13418.6 KFX87926.1 - 7.3e-34 115.5 7.2 1.8e-06 27.8 0.0 6.7 7 0 0 7 7 7 6 Galactose oxidase, central domain Kelch_6 PF13964.6 KFX87926.1 - 4.2e-29 99.8 9.3 1.3e-09 38.0 1.0 6.5 5 1 1 6 6 6 6 Kelch motif Kelch_3 PF13415.6 KFX87926.1 - 3.3e-28 97.4 10.3 9.8e-06 25.7 0.1 5.8 5 0 0 5 5 5 5 Galactose oxidase, central domain Kelch_5 PF13854.6 KFX87926.1 - 1.4e-27 95.2 8.8 1.1e-07 31.7 0.2 6.5 6 0 0 6 6 6 5 Kelch motif Kelch_1 PF01344.25 KFX87926.1 - 8.8e-26 89.2 7.6 2.5e-08 33.4 0.4 6.4 6 0 0 6 6 6 5 Kelch motif Kelch_2 PF07646.15 KFX87926.1 - 1.6e-19 69.1 10.0 3.4e-06 26.8 0.7 6.5 6 0 0 6 6 6 4 Kelch motif LRR_8 PF13855.6 KFX87927.1 - 1.2e-06 28.2 1.5 3.6e-06 26.6 1.5 1.8 1 0 0 1 1 1 1 Leucine rich repeat LRR_4 PF12799.7 KFX87927.1 - 0.00022 21.6 1.6 0.18 12.3 0.1 2.8 2 0 0 2 2 2 2 Leucine Rich repeats (2 copies) Phosducin PF02114.16 KFX87928.1 - 3.3e-10 39.3 0.1 5e-10 38.8 0.1 1.2 1 0 0 1 1 1 1 Phosducin Ribosomal_S27e PF01667.17 KFX87929.1 - 1e-28 98.8 6.7 1.3e-28 98.5 6.7 1.1 1 0 0 1 1 1 1 Ribosomal protein S27 zf-C2HC5 PF06221.13 KFX87929.1 - 0.39 10.7 6.3 2 8.4 4.2 2.3 2 1 0 2 2 2 0 Putative zinc finger motif, C2HC5-type SLD3 PF08639.10 KFX87932.1 - 0.52 9.0 8.6 0.54 9.0 8.6 1.0 1 0 0 1 1 1 0 DNA replication regulator SLD3 Cwf_Cwc_15 PF04889.12 KFX87932.1 - 0.85 9.3 15.3 0.98 9.1 15.3 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Asp PF00026.23 KFX87933.1 - 5.5e-105 351.3 0.2 7.4e-105 350.8 0.2 1.2 1 0 0 1 1 1 1 Eukaryotic aspartyl protease CLP1_P PF16575.5 KFX87933.1 - 1.3e-32 113.1 0.0 3.8e-32 111.6 0.0 1.8 1 1 0 1 1 1 1 mRNA cleavage and polyadenylation factor CLP1 P-loop TAXi_N PF14543.6 KFX87933.1 - 1.1e-14 55.1 0.6 3.6e-13 50.1 0.6 2.4 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 KFX87933.1 - 0.018 15.7 0.1 18 6.0 0.0 3.3 2 1 0 2 2 2 0 Aspartyl protease TAXi_C PF14541.6 KFX87933.1 - 0.021 14.6 0.0 0.093 12.5 0.0 2.0 1 1 0 1 1 1 0 Xylanase inhibitor C-terminal AAA_22 PF13401.6 KFX87933.1 - 0.11 12.8 0.0 0.21 11.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 KFX87933.1 - 0.14 12.5 0.0 0.43 11.0 0.0 1.8 1 0 0 1 1 1 0 RNA helicase AAA_33 PF13671.6 KFX87933.1 - 0.18 12.0 0.0 0.37 10.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain PSD5 PF07637.11 KFX87943.1 - 4.6 7.7 8.5 1.3 9.4 0.6 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF1595) SET PF00856.28 KFX87944.1 - 0.12 12.8 0.0 0.35 11.2 0.0 1.8 2 0 0 2 2 2 0 SET domain WD40 PF00400.32 KFX87947.1 - 1.1e-54 181.1 14.3 6.6e-09 36.3 0.2 7.4 7 0 0 7 7 7 7 WD domain, G-beta repeat Tup_N PF08581.10 KFX87947.1 - 1.6e-19 70.0 8.0 3e-19 69.1 8.0 1.5 1 0 0 1 1 1 1 Tup N-terminal ANAPC4_WD40 PF12894.7 KFX87947.1 - 6e-16 58.5 0.0 8.1e-05 22.9 0.0 5.7 2 1 3 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 KFX87947.1 - 2e-07 30.6 0.0 0.02 14.2 0.0 4.4 4 1 1 5 5 5 2 WD40-like domain Ge1_WD40 PF16529.5 KFX87947.1 - 5e-06 25.7 0.2 0.8 8.6 0.0 5.2 1 1 4 5 5 5 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 KFX87947.1 - 0.0015 17.3 0.0 1.2 7.7 0.0 3.0 1 1 2 3 3 3 2 Nucleoporin Nup120/160 Golgin_A5 PF09787.9 KFX87947.1 - 0.0026 17.3 1.7 0.0038 16.8 1.7 1.1 1 0 0 1 1 1 1 Golgin subfamily A member 5 DUF3037 PF11236.8 KFX87947.1 - 0.005 17.3 0.2 0.0099 16.3 0.2 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3037) Nbas_N PF15492.6 KFX87947.1 - 0.0069 15.8 0.0 3.4 6.9 0.0 2.8 2 1 1 3 3 3 2 Neuroblastoma-amplified sequence, N terminal PD40 PF07676.12 KFX87947.1 - 0.021 14.7 0.0 12 6.0 0.0 4.3 5 0 0 5 5 5 0 WD40-like Beta Propeller Repeat Cytochrom_D1 PF02239.16 KFX87947.1 - 0.068 11.7 0.7 0.76 8.2 0.4 2.3 1 1 1 2 2 2 0 Cytochrome D1 heme domain zf-UBP PF02148.19 KFX87949.1 - 2.4e-17 63.0 4.8 4e-16 59.1 6.4 1.9 2 0 0 2 2 2 1 Zn-finger in ubiquitin-hydrolases and other protein Tup_N PF08581.10 KFX87949.1 - 0.023 15.0 3.7 0.32 11.3 1.1 2.6 2 0 0 2 2 2 0 Tup N-terminal P4Ha_N PF08336.11 KFX87949.1 - 0.14 12.2 1.3 0.21 11.6 0.3 1.8 2 0 0 2 2 2 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region Cnn_1N PF07989.11 KFX87949.1 - 0.19 11.9 4.4 0.24 11.6 0.7 2.4 2 0 0 2 2 2 0 Centrosomin N-terminal motif 1 DUF745 PF05335.13 KFX87949.1 - 0.47 10.2 9.4 1 9.0 5.0 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF745) TSNAXIP1_N PF15739.5 KFX87949.1 - 0.49 10.8 8.2 0.44 10.9 1.0 2.3 2 0 0 2 2 2 0 Translin-associated factor X-interacting N-terminus YabA PF06156.13 KFX87949.1 - 0.57 10.9 7.0 0.35 11.5 0.8 2.4 1 1 1 2 2 2 0 Initiation control protein YabA DUF1664 PF07889.12 KFX87949.1 - 0.93 9.5 4.8 5.3 7.1 0.6 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) zf-CpG_bind_C PF12269.8 KFX87949.1 - 1 9.1 5.5 0.42 10.4 1.0 2.3 1 1 1 2 2 2 0 CpG binding protein zinc finger C terminal domain Tropomyosin_1 PF12718.7 KFX87949.1 - 1.8 8.7 13.9 0.12 12.5 5.4 2.2 1 1 1 2 2 2 0 Tropomyosin like CENP-H PF05837.12 KFX87949.1 - 2 8.9 10.6 0.2 12.1 0.8 2.5 1 1 1 2 2 2 0 Centromere protein H (CENP-H) FlaC_arch PF05377.11 KFX87949.1 - 3.4 8.1 4.7 5.5 7.5 0.1 2.7 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) Cep57_CLD_2 PF14197.6 KFX87949.1 - 4 7.6 9.0 12 6.0 2.9 2.7 1 1 0 2 2 2 0 Centrosome localisation domain of PPC89 DivIVA PF05103.13 KFX87949.1 - 4.5 7.4 9.1 2.1 8.4 0.7 2.5 2 1 1 3 3 3 0 DivIVA protein CENP-F_leu_zip PF10473.9 KFX87949.1 - 5.1 7.1 15.9 7.1 6.7 13.6 2.2 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 ZapB PF06005.12 KFX87949.1 - 7.2 7.1 12.0 0.66 10.5 1.8 3.0 1 1 1 2 2 2 0 Cell division protein ZapB Zn_clus PF00172.18 KFX87957.1 - 4.6e-07 29.8 9.7 7.9e-07 29.1 9.7 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 KFX87957.1 - 2.4e-06 26.6 0.3 3.3e-06 26.2 0.3 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Fungal_trans_2 PF11951.8 KFX87961.1 - 1.5e-14 53.7 0.5 2.8e-14 52.7 0.5 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain DLH PF01738.18 KFX87962.1 - 1.9e-14 53.7 0.0 2.4e-14 53.4 0.0 1.2 1 0 0 1 1 1 1 Dienelactone hydrolase family NAD_binding_4 PF07993.12 KFX87963.1 - 1.6e-72 243.8 0.0 2.3e-72 243.3 0.0 1.2 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.28 KFX87963.1 - 3.6e-71 240.0 0.0 6.2e-71 239.2 0.0 1.4 1 0 0 1 1 1 1 AMP-binding enzyme Epimerase PF01370.21 KFX87963.1 - 1e-10 41.5 0.0 2e-10 40.5 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.25 KFX87963.1 - 3.1e-08 33.8 0.0 6.8e-08 32.8 0.0 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site 3Beta_HSD PF01073.19 KFX87963.1 - 4.4e-08 32.5 0.0 1.3e-07 30.9 0.0 1.7 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 KFX87963.1 - 0.00092 19.1 0.2 0.0045 16.9 0.2 2.2 1 1 0 1 1 1 1 NAD(P)H-binding AMP-binding_C PF13193.6 KFX87963.1 - 0.00093 20.1 0.0 0.0071 17.3 0.0 2.5 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain GDP_Man_Dehyd PF16363.5 KFX87963.1 - 0.012 15.0 0.0 0.02 14.3 0.0 1.3 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 KFX87963.1 - 0.03 13.5 0.0 0.075 12.1 0.0 1.6 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein AAR2 PF05282.11 KFX87963.1 - 0.11 11.9 0.0 0.24 10.7 0.0 1.5 1 0 0 1 1 1 0 AAR2 protein RmlD_sub_bind PF04321.17 KFX87963.1 - 0.12 11.4 0.1 0.84 8.7 0.1 2.1 1 1 0 1 1 1 0 RmlD substrate binding domain OPT PF03169.15 KFX87977.1 - 2.4e-183 611.1 22.4 2.8e-183 610.9 22.4 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein Zip PF02535.22 KFX87989.1 - 2.6e-17 63.1 1.5 3.4e-17 62.7 1.5 1.2 1 0 0 1 1 1 1 ZIP Zinc transporter DUF2040 PF09745.9 KFX87990.1 - 6.1e-36 123.1 17.3 6.1e-36 123.1 17.3 3.0 3 0 0 3 3 3 2 Coiled-coil domain-containing protein 55 (DUF2040) RINGv PF12906.7 KFX87993.1 - 8.8e-09 35.4 4.2 1.2e-08 34.9 0.8 2.3 2 0 0 2 2 2 1 RING-variant domain Xan_ur_permease PF00860.20 KFX87993.1 - 0.095 11.4 0.2 0.4 9.3 0.0 1.8 2 0 0 2 2 2 0 Permease family zf-RING_2 PF13639.6 KFX87993.1 - 0.29 11.5 4.9 1.1 9.6 1.5 2.2 2 0 0 2 2 2 0 Ring finger domain Proteasome PF00227.26 KFX87994.1 - 3.6e-57 192.9 0.0 4.5e-33 114.3 0.0 2.1 2 0 0 2 2 2 2 Proteasome subunit Proteasome_A_N PF10584.9 KFX87994.1 - 2e-10 40.1 0.4 5.1e-10 38.9 0.0 1.8 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature PQQ PF01011.21 KFX87995.1 - 0.00013 21.7 1.1 0.4 10.7 0.0 3.7 3 0 0 3 3 3 2 PQQ enzyme repeat WD40 PF00400.32 KFX87995.1 - 0.00029 21.6 17.0 0.11 13.4 2.6 5.6 5 0 0 5 5 5 3 WD domain, G-beta repeat GRDP-like PF07173.12 KFX87996.1 - 6.6e-22 78.7 11.5 1.5e-12 48.4 0.2 4.7 1 1 3 4 4 4 4 Glycine-rich domain-containing protein-like MFS_1 PF07690.16 KFX87997.1 - 2.2e-30 105.8 30.6 1.4e-27 96.6 19.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily PgaD PF13994.6 KFX87997.1 - 0.023 14.7 0.0 12 5.9 0.0 2.7 2 0 0 2 2 2 0 PgaD-like protein Lipase_GDSL_2 PF13472.6 KFX87998.1 - 2.1e-20 73.9 0.2 3.7e-20 73.0 0.2 1.4 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 KFX87998.1 - 1.2e-16 61.3 0.0 1.4e-16 61.1 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_3 PF14606.6 KFX87998.1 - 0.073 13.2 0.0 0.92 9.6 0.0 2.1 2 0 0 2 2 2 0 GDSL-like Lipase/Acylhydrolase family Cellulase PF00150.18 KFX88006.1 - 1.6e-08 34.3 0.2 1.6e-08 34.3 0.2 1.6 2 0 0 2 2 2 1 Cellulase (glycosyl hydrolase family 5) SR-25 PF10500.9 KFX88006.1 - 0.14 11.7 34.5 0.26 10.9 34.5 1.4 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein OAD_gamma PF04277.13 KFX88006.1 - 4.5 7.9 4.8 6.6 7.4 0.1 2.4 2 0 0 2 2 2 0 Oxaloacetate decarboxylase, gamma chain Transket_pyr PF02779.24 KFX88007.1 - 9.4e-43 145.9 0.0 1.5e-42 145.3 0.0 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 KFX88007.1 - 6.8e-32 110.0 0.0 1.2e-31 109.2 0.0 1.4 1 0 0 1 1 1 1 Transketolase, C-terminal domain PFOR_II PF17147.4 KFX88007.1 - 0.00081 19.7 0.0 0.0018 18.5 0.0 1.6 1 0 0 1 1 1 1 Pyruvate:ferredoxin oxidoreductase core domain II MAPEG PF01124.18 KFX88010.1 - 2.7e-11 43.5 3.5 3.3e-11 43.2 3.5 1.1 1 0 0 1 1 1 1 MAPEG family ADH_N PF08240.12 KFX88014.1 - 1.7e-25 89.0 1.8 1.7e-25 89.0 1.8 2.1 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KFX88014.1 - 2e-19 69.8 0.5 4.1e-19 68.9 0.5 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 KFX88014.1 - 0.0022 17.4 1.3 0.0039 16.5 1.3 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Sacchrp_dh_NADP PF03435.18 KFX88014.1 - 0.007 16.6 0.1 0.013 15.8 0.1 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain NAD_binding_7 PF13241.6 KFX88014.1 - 0.15 12.6 0.1 0.36 11.3 0.1 1.6 1 0 0 1 1 1 0 Putative NAD(P)-binding Imm70 PF15601.6 KFX88014.1 - 0.17 11.4 0.0 0.36 10.4 0.0 1.4 1 0 0 1 1 1 0 Immunity protein 70 Zn_clus PF00172.18 KFX88015.1 - 3.1e-06 27.2 13.9 5.8e-06 26.3 13.9 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 KFX88015.1 - 1.5e-05 24.0 0.2 0.16 10.8 0.0 2.4 2 0 0 2 2 2 2 Fungal specific transcription factor domain DUF2070 PF09843.9 KFX88016.1 - 0.068 11.5 6.8 0.12 10.7 6.8 1.4 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) 2TM PF13239.6 KFX88016.1 - 0.19 12.1 5.0 0.17 12.2 1.1 2.4 2 0 0 2 2 2 0 2TM domain Ion_trans PF00520.31 KFX88016.1 - 0.26 10.5 5.6 0.24 10.6 2.9 2.1 2 0 0 2 2 2 0 Ion transport protein DUF983 PF06170.12 KFX88016.1 - 4.7 7.7 9.0 1.3 9.4 2.3 3.3 2 1 0 2 2 2 0 Protein of unknown function (DUF983) Erf4 PF10256.9 KFX88017.1 - 0.028 14.5 0.0 0.051 13.7 0.0 1.4 1 0 0 1 1 1 0 Golgin subfamily A member 7/ERF4 family Amidase PF01425.21 KFX88022.1 - 8.5e-12 44.8 0.2 1e-11 44.5 0.2 1.1 1 0 0 1 1 1 1 Amidase RAC_head PF16717.5 KFX88023.1 - 1.8e-32 112.2 2.6 1.8e-32 112.2 2.6 3.5 3 1 0 3 3 3 1 Ribosome-associated complex head domain DnaJ PF00226.31 KFX88023.1 - 6.4e-19 67.9 1.1 2.6e-18 65.9 1.1 2.2 1 0 0 1 1 1 1 DnaJ domain PspB PF06667.12 KFX88023.1 - 0.094 12.8 1.0 0.28 11.2 1.0 1.8 1 0 0 1 1 1 0 Phage shock protein B V_ATPase_I PF01496.19 KFX88023.1 - 0.46 8.3 9.2 0.73 7.7 9.2 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Complex1_LYR PF05347.15 KFX88024.1 - 0.00011 22.2 0.0 0.00019 21.4 0.0 1.5 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Abhydrolase_3 PF07859.13 KFX88025.1 - 4.3e-16 59.4 0.1 4.3e-14 52.9 0.0 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KFX88025.1 - 1.1e-09 38.1 0.0 0.00013 21.5 0.0 2.1 2 0 0 2 2 2 2 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 KFX88025.1 - 0.03 13.6 0.0 1.3 8.2 0.0 2.2 2 0 0 2 2 2 0 Serine aminopeptidase, S33 DLH PF01738.18 KFX88025.1 - 0.048 13.2 0.0 3.4 7.2 0.0 2.1 2 0 0 2 2 2 0 Dienelactone hydrolase family GDA1_CD39 PF01150.17 KFX88030.1 - 2e-13 49.8 0.0 2.6e-13 49.5 0.0 1.1 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family DUF4594 PF15266.6 KFX88043.1 - 0.97 9.7 8.8 0.16 12.3 4.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4594) Inp1 PF12634.7 KFX88052.1 - 1.1e-40 138.8 0.0 2.8e-40 137.5 0.0 1.7 1 0 0 1 1 1 1 Inheritance of peroxisomes protein 1 Mog1 PF04603.12 KFX88053.1 - 1e-39 136.1 0.0 1.2e-39 135.8 0.0 1.1 1 0 0 1 1 1 1 Ran-interacting Mog1 protein Acetyltransf_10 PF13673.7 KFX88054.1 - 8.5e-08 32.2 0.0 1.7e-07 31.2 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KFX88054.1 - 1.4e-06 28.5 0.0 2.9e-06 27.5 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KFX88054.1 - 3.1e-06 27.5 0.0 6.6e-06 26.5 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain UDG PF03167.19 KFX88054.1 - 0.0014 18.6 0.0 0.003 17.6 0.0 1.6 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily FR47 PF08445.10 KFX88054.1 - 0.0022 17.9 0.0 0.0055 16.7 0.0 1.6 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.7 KFX88054.1 - 0.061 13.4 0.0 0.35 10.9 0.0 2.2 2 1 0 2 2 2 0 Acetyltransferase (GNAT) domain CCSAP PF15748.5 KFX88057.1 - 0.12 12.5 1.9 0.13 12.5 1.9 1.0 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated CAP_N PF01213.19 KFX88057.1 - 2.4 7.5 8.4 2.5 7.5 8.4 1.1 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal RNA12 PF10443.9 KFX88058.1 - 2.2e-163 544.1 0.9 5e-163 543.0 0.9 1.6 1 0 0 1 1 1 1 RNA12 protein RRM_1 PF00076.22 KFX88058.1 - 0.00045 20.0 0.0 0.0035 17.1 0.0 2.4 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) ATPase_2 PF01637.18 KFX88058.1 - 0.0051 16.8 0.0 0.012 15.5 0.0 1.6 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea Picorna_P3A PF06363.11 KFX88058.1 - 0.011 15.6 0.0 0.029 14.2 0.0 1.6 1 0 0 1 1 1 0 Picornaviridae P3A protein AAA_16 PF13191.6 KFX88058.1 - 0.044 14.2 2.5 0.19 12.1 0.0 3.0 2 1 1 3 3 3 0 AAA ATPase domain SicP-binding PF09119.10 KFX88059.1 - 0.067 13.2 0.0 0.12 12.3 0.0 1.4 1 0 0 1 1 1 0 SicP binding YqzE PF14038.6 KFX88060.1 - 2.5 8.2 5.1 0.64 10.1 0.4 2.3 2 0 0 2 2 2 0 YqzE-like protein Peroxin-3 PF04882.12 KFX88061.1 - 2.5e-173 577.4 0.0 3e-173 577.2 0.0 1.0 1 0 0 1 1 1 1 Peroxin-3 Sybindin PF04099.12 KFX88062.1 - 3.2e-26 92.0 0.0 3.9e-26 91.7 0.0 1.1 1 0 0 1 1 1 1 Sybindin-like family Sedlin_N PF04628.13 KFX88062.1 - 0.0061 16.7 0.2 0.0087 16.2 0.2 1.2 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region FAD_binding_3 PF01494.19 KFX88070.1 - 7.4e-74 249.1 0.0 9.6e-74 248.7 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.12 KFX88070.1 - 8.4e-40 136.5 0.0 1.3e-39 135.9 0.0 1.3 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain Pyr_redox_2 PF07992.14 KFX88070.1 - 0.00054 19.3 0.0 0.01 15.1 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KFX88070.1 - 0.011 16.3 0.0 0.073 13.6 0.0 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KFX88070.1 - 0.012 15.8 0.0 0.027 14.7 0.0 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KFX88070.1 - 0.023 14.3 0.1 0.31 10.6 0.0 2.2 1 1 0 2 2 2 0 FAD dependent oxidoreductase UDPG_MGDP_dh_N PF03721.14 KFX88070.1 - 0.027 14.0 0.0 0.059 12.9 0.0 1.5 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain ApbA PF02558.16 KFX88070.1 - 0.088 12.5 0.0 0.2 11.3 0.0 1.6 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Lycopene_cycl PF05834.12 KFX88070.1 - 0.089 11.8 0.0 0.16 11.0 0.0 1.4 1 0 0 1 1 1 0 Lycopene cyclase protein XdhC_C PF13478.6 KFX88070.1 - 0.1 13.1 0.0 0.23 12.0 0.0 1.6 1 0 0 1 1 1 0 XdhC Rossmann domain DUF3337 PF11816.8 KFX88071.1 - 5.3e-52 176.2 0.0 1.1e-51 175.1 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3337) WD40 PF00400.32 KFX88071.1 - 7.7e-18 64.5 8.8 0.0012 19.6 0.1 6.9 6 0 0 6 6 6 4 WD domain, G-beta repeat DDHD PF02862.17 KFX88071.1 - 1.8e-16 61.0 0.0 1.8e-16 61.0 0.0 3.9 4 2 2 6 6 6 1 DDHD domain ANAPC4_WD40 PF12894.7 KFX88071.1 - 0.0087 16.3 0.2 0.034 14.5 0.0 2.1 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KFX88071.1 - 0.027 13.1 1.3 0.11 11.1 0.2 2.0 2 0 0 2 2 2 0 Nucleoporin Nup120/160 Lectin_leg-like PF03388.13 KFX88073.1 - 2e-66 223.6 0.0 2.9e-66 223.1 0.0 1.2 1 0 0 1 1 1 1 Legume-like lectin family Bact_lectin PF18483.1 KFX88073.1 - 6.9e-07 29.5 0.0 1.1e-06 28.8 0.0 1.3 1 1 0 1 1 1 1 Bacterial lectin Lectin_legB PF00139.19 KFX88073.1 - 1.5e-05 24.7 0.0 0.044 13.3 0.0 2.5 2 0 0 2 2 2 2 Legume lectin domain ATG27 PF09451.10 KFX88073.1 - 0.043 13.7 0.1 0.051 13.4 0.1 1.2 1 0 0 1 1 1 0 Autophagy-related protein 27 zf-Tim10_DDP PF02953.15 KFX88074.1 - 4.9e-24 83.8 2.2 6.1e-24 83.4 2.2 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger DUF3361 PF11841.8 KFX88074.1 - 0.043 13.8 0.1 0.39 10.6 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3361) Abhydrolase_4 PF08386.10 KFX88074.1 - 0.099 12.8 0.0 1.4 9.1 0.0 2.1 1 1 0 1 1 1 0 TAP-like protein adh_short PF00106.25 KFX88080.1 - 2.4e-38 131.6 1.9 3.3e-38 131.1 1.9 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KFX88080.1 - 2.3e-30 105.9 0.5 3e-30 105.5 0.5 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KFX88080.1 - 3.4e-10 40.1 5.0 6.6e-09 35.9 5.0 2.1 1 1 0 1 1 1 1 KR domain OGFr_N PF04664.13 KFX88081.1 - 0.0015 18.1 0.8 0.12 11.9 0.0 2.9 3 0 0 3 3 3 2 Opioid growth factor receptor (OGFr) conserved region Oxysterol_BP PF01237.18 KFX88084.1 - 2.9e-87 292.9 0.0 1e-84 284.6 0.0 2.0 1 1 0 1 1 1 1 Oxysterol-binding protein PCI PF01399.27 KFX88086.1 - 1.5e-11 44.7 0.0 4.8e-11 43.1 0.0 1.9 1 0 0 1 1 1 1 PCI domain F-box-like PF12937.7 KFX88086.1 - 0.00023 21.0 0.0 0.00048 20.0 0.0 1.6 1 0 0 1 1 1 1 F-box-like RPN7 PF10602.9 KFX88086.1 - 0.00024 20.9 0.1 0.00048 19.9 0.1 1.4 1 0 0 1 1 1 1 26S proteasome subunit RPN7 ComR_TPR PF18710.1 KFX88086.1 - 0.04 13.5 0.0 0.13 11.8 0.0 1.6 1 1 0 1 1 1 0 ComR tetratricopeptide TPR_19 PF14559.6 KFX88086.1 - 0.091 13.3 1.4 0.24 11.9 1.2 1.8 1 1 0 1 1 1 0 Tetratricopeptide repeat Cob_adeno_trans PF01923.18 KFX88098.1 - 0.052 13.7 0.4 0.052 13.7 0.4 1.8 2 0 0 2 2 2 0 Cobalamin adenosyltransferase DUF3138 PF11336.8 KFX88098.1 - 2.1 6.8 5.9 2.7 6.5 5.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) EthD PF07110.11 KFX88100.1 - 7.9e-10 39.8 0.4 1.5e-09 38.8 0.4 1.5 1 1 0 1 1 1 1 EthD domain MmlI PF09448.10 KFX88100.1 - 0.0014 19.0 0.0 0.002 18.6 0.0 1.3 1 0 0 1 1 1 1 Methylmuconolactone methyl-isomerase LMBR1 PF04791.16 KFX88119.1 - 5.3e-122 408.3 10.1 6e-122 408.2 10.1 1.0 1 0 0 1 1 1 1 LMBR1-like membrane protein DUF1515 PF07439.11 KFX88119.1 - 0.71 9.9 4.2 2.4 8.2 0.1 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF1515) Methyltransf_16 PF10294.9 KFX88120.1 - 1.4e-17 64.0 0.0 2e-17 63.4 0.0 1.2 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_25 PF13649.6 KFX88120.1 - 1.4e-05 25.7 0.0 0.00011 22.8 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KFX88120.1 - 3.1e-05 23.9 0.0 4.6e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 KFX88120.1 - 0.0029 17.0 0.0 0.0041 16.6 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Cons_hypoth95 PF03602.15 KFX88120.1 - 0.023 14.3 0.0 0.035 13.7 0.0 1.2 1 0 0 1 1 1 0 Conserved hypothetical protein 95 Methyltransf_11 PF08241.12 KFX88120.1 - 0.033 14.8 0.0 0.14 12.8 0.0 1.9 1 1 0 1 1 1 0 Methyltransferase domain MTS PF05175.14 KFX88120.1 - 0.037 13.6 0.0 0.21 11.1 0.0 2.1 1 1 0 1 1 1 0 Methyltransferase small domain Methyltransf_31 PF13847.6 KFX88120.1 - 0.064 13.1 0.0 0.35 10.7 0.0 1.9 1 1 0 1 1 1 0 Methyltransferase domain NNMT_PNMT_TEMT PF01234.17 KFX88120.1 - 0.15 11.2 0.0 0.22 10.7 0.0 1.2 1 0 0 1 1 1 0 NNMT/PNMT/TEMT family Methyltransf_12 PF08242.12 KFX88120.1 - 0.18 12.6 0.0 1.1 10.0 0.0 2.0 1 1 0 1 1 1 0 Methyltransferase domain PCMT PF01135.19 KFX88120.1 - 0.22 11.2 0.0 0.35 10.6 0.0 1.4 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Myb_DNA-binding PF00249.31 KFX88133.1 - 5.9e-24 84.0 0.7 1.3e-12 47.7 0.0 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KFX88133.1 - 4.6e-16 58.8 0.5 1.5e-11 44.4 0.0 2.5 1 1 1 2 2 2 2 Myb-like DNA-binding domain THEG4 PF15834.5 KFX88133.1 - 0.055 13.5 3.0 0.074 13.0 1.8 1.7 1 1 1 2 2 2 0 Testis highly expressed protein 4 Sigma70_r4_2 PF08281.12 KFX88133.1 - 0.073 12.8 0.0 0.17 11.6 0.0 1.6 1 0 0 1 1 1 0 Sigma-70, region 4 TPR_1 PF00515.28 KFX88135.1 - 3.2e-24 83.7 9.9 0.00015 21.4 0.1 7.3 6 1 1 7 7 7 5 Tetratricopeptide repeat TPR_2 PF07719.17 KFX88135.1 - 1.2e-18 65.6 13.9 0.0022 18.0 0.1 7.3 6 1 1 7 7 7 4 Tetratricopeptide repeat TPR_11 PF13414.6 KFX88135.1 - 5.6e-13 48.3 8.6 0.0014 18.2 0.0 5.6 3 2 2 5 5 5 4 TPR repeat TPR_9 PF13371.6 KFX88135.1 - 5.7e-11 42.4 0.8 9.8e-06 25.6 0.1 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 KFX88135.1 - 2.6e-09 36.6 7.9 0.034 14.3 0.1 6.1 6 1 0 6 6 6 3 Tetratricopeptide repeat TPR_17 PF13431.6 KFX88135.1 - 6.5e-07 29.3 8.3 0.57 10.7 0.0 5.3 5 1 0 5 5 5 3 Tetratricopeptide repeat TPR_16 PF13432.6 KFX88135.1 - 2.3e-06 28.1 13.7 0.017 15.8 0.1 4.6 4 2 1 5 5 5 3 Tetratricopeptide repeat TPR_7 PF13176.6 KFX88135.1 - 3.4e-06 26.7 2.5 0.69 10.1 0.0 3.9 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 KFX88135.1 - 1.1e-05 25.7 14.6 0.08 13.2 0.8 4.7 3 2 1 4 4 4 3 Tetratricopeptide repeat TPR_19 PF14559.6 KFX88135.1 - 1.8e-05 25.2 7.2 0.26 11.8 0.1 4.2 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.6 KFX88135.1 - 0.0025 18.5 5.6 1.9 9.5 0.1 4.7 4 1 1 5 5 5 1 Tetratricopeptide repeat AP3D1 PF06375.11 KFX88135.1 - 0.013 15.7 1.4 0.024 14.9 1.4 1.4 1 0 0 1 1 1 0 AP-3 complex subunit delta-1 TPR_10 PF13374.6 KFX88135.1 - 0.13 12.2 9.4 12 5.9 0.2 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat MIT PF04212.18 KFX88135.1 - 0.48 10.5 4.5 3.2 7.9 0.1 3.4 3 0 0 3 3 3 0 MIT (microtubule interacting and transport) domain SHNi-TPR PF10516.9 KFX88135.1 - 0.78 9.2 10.2 54 3.4 0.0 5.4 6 0 0 6 6 6 0 SHNi-TPR TPR_6 PF13174.6 KFX88135.1 - 6.5 7.6 7.6 32 5.5 0.1 4.0 4 0 0 4 4 3 0 Tetratricopeptide repeat DUF3455 PF11937.8 KFX88136.1 - 3e-35 122.0 0.0 3.7e-35 121.6 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3455) Ecl1 PF12855.7 KFX88157.1 - 3.6e-12 47.8 23.1 4.7e-12 47.4 23.1 1.1 1 0 0 1 1 1 1 ECL1/2/3 zinc binding proteins Opi1 PF08618.10 KFX88157.1 - 0.0019 17.6 4.8 0.0023 17.3 4.8 1.1 1 0 0 1 1 1 1 Transcription factor Opi1 NAD_binding_1 PF00175.21 KFX88160.1 - 6e-10 39.7 0.0 1.6e-05 25.5 0.0 2.1 2 0 0 2 2 2 2 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 KFX88160.1 - 8.8e-06 26.0 0.0 1.8e-05 25.0 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.12 KFX88160.1 - 0.0047 17.1 0.0 0.008 16.3 0.0 1.3 1 0 0 1 1 1 1 Ferric reductase NAD binding domain DnaJ PF00226.31 KFX88161.1 - 1.6e-21 76.2 0.4 2.7e-21 75.4 0.4 1.4 1 0 0 1 1 1 1 DnaJ domain Abhydrolase_1 PF00561.20 KFX88164.1 - 1.4e-08 34.7 0.0 4.8e-08 33.0 0.0 1.7 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KFX88164.1 - 3.8e-06 27.7 0.1 5.1e-06 27.2 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KFX88164.1 - 0.0013 18.1 0.3 0.0031 16.8 0.0 1.7 1 1 1 2 2 2 1 Serine aminopeptidase, S33 HNH_2 PF13391.6 KFX88165.1 - 6.9e-16 58.1 0.0 1.5e-15 57.1 0.0 1.6 1 0 0 1 1 1 1 HNH endonuclease Mpv17_PMP22 PF04117.12 KFX88168.1 - 6.6e-16 58.3 0.2 6.6e-16 58.3 0.2 1.7 2 0 0 2 2 2 1 Mpv17 / PMP22 family NQR2_RnfD_RnfE PF03116.15 KFX88168.1 - 0.008 15.6 0.3 0.01 15.3 0.3 1.1 1 0 0 1 1 1 1 NQR2, RnfD, RnfE family Glyco_transf_22 PF03901.17 KFX88169.1 - 8.2e-79 265.8 12.7 9.6e-79 265.5 12.7 1.0 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family SNF5 PF04855.12 KFX88176.1 - 5.9e-63 212.8 0.0 1.8e-61 208.0 0.0 2.4 1 1 0 1 1 1 1 SNF5 / SMARCB1 / INI1 Peptidase_M24 PF00557.24 KFX88177.1 - 3.2e-06 27.0 0.0 4.4e-06 26.5 0.0 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 Imm26 PF15428.6 KFX88177.1 - 0.12 12.6 0.0 0.32 11.3 0.0 1.8 1 0 0 1 1 1 0 Immunity protein 26 TIP41 PF04176.13 KFX88178.1 - 5e-67 224.7 0.1 6.6e-67 224.3 0.1 1.2 1 0 0 1 1 1 1 TIP41-like family Pkinase PF00069.25 KFX88179.1 - 2.2e-73 246.9 0.0 2.7e-73 246.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFX88179.1 - 1.8e-42 145.4 0.0 2.4e-42 145.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KFX88179.1 - 9.4e-07 28.4 0.0 1.2e-05 24.8 0.0 2.0 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 KFX88179.1 - 0.0015 17.9 0.2 0.0025 17.2 0.2 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 KFX88179.1 - 0.0088 15.7 0.0 0.071 12.7 0.0 2.0 1 1 1 2 2 2 1 RIO1 family Haspin_kinase PF12330.8 KFX88179.1 - 0.012 14.6 0.0 0.018 14.0 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain YrbL-PhoP_reg PF10707.9 KFX88179.1 - 0.063 12.8 0.1 0.13 11.7 0.1 1.6 1 1 0 1 1 1 0 PhoP regulatory network protein YrbL FTA2 PF13095.6 KFX88179.1 - 0.073 12.7 0.0 0.19 11.3 0.0 1.6 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Pkinase_fungal PF17667.1 KFX88179.1 - 0.093 11.5 0.1 0.2 10.4 0.0 1.3 1 1 0 1 1 1 0 Fungal protein kinase Peptidase_M76 PF09768.9 KFX88180.1 - 3e-72 241.9 2.0 3.9e-72 241.6 2.0 1.1 1 0 0 1 1 1 1 Peptidase M76 family Peptidase_M91 PF14891.6 KFX88180.1 - 0.019 15.3 1.7 0.022 15.1 0.5 2.0 1 1 1 2 2 2 0 Effector protein Tox-MPTase2 PF15638.6 KFX88180.1 - 0.025 14.4 0.0 0.039 13.7 0.0 1.3 1 0 0 1 1 1 0 Metallopeptidase toxin 2 SprT-like PF10263.9 KFX88180.1 - 0.041 13.7 2.5 0.056 13.3 1.0 1.8 1 1 1 2 2 2 0 SprT-like family DUF2268 PF10026.9 KFX88180.1 - 0.11 12.0 0.0 0.18 11.4 0.0 1.3 1 0 0 1 1 1 0 Predicted Zn-dependent protease (DUF2268) zf-CW PF07496.15 KFX88180.1 - 0.14 12.2 4.3 1.6 8.8 0.1 2.8 3 0 0 3 3 3 0 CW-type Zinc Finger AA_kinase PF00696.28 KFX88181.1 - 1.8e-40 139.0 2.3 2.5e-40 138.6 2.3 1.2 1 0 0 1 1 1 1 Amino acid kinase family PUA PF01472.20 KFX88181.1 - 1.5e-13 50.5 2.2 8.5e-08 32.0 0.2 2.9 3 0 0 3 3 3 2 PUA domain RRN9 PF10680.9 KFX88187.1 - 4.3e-16 58.9 1.3 8.9e-16 57.9 0.2 2.1 2 0 0 2 2 2 1 RNA polymerase I specific transcription initiation factor UL16 PF17622.2 KFX88187.1 - 0.21 11.2 0.1 0.32 10.6 0.1 1.2 1 0 0 1 1 1 0 Viral unique long protein 16 COPI_C PF06957.11 KFX88187.1 - 0.34 9.6 1.1 0.48 9.1 1.1 1.2 1 0 0 1 1 1 0 Coatomer (COPI) alpha subunit C-terminus Pescadillo_N PF06732.11 KFX88188.1 - 3.2e-121 404.1 0.0 7.4e-121 402.9 0.0 1.5 1 0 0 1 1 1 1 Pescadillo N-terminus BRCT PF00533.26 KFX88188.1 - 0.00021 21.6 0.0 0.0013 19.1 0.0 2.3 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 KFX88188.1 - 0.0098 16.3 0.0 0.041 14.3 0.0 2.1 1 1 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain LIG3_BRCT PF16759.5 KFX88188.1 - 0.22 11.9 0.2 0.67 10.3 0.2 1.9 1 1 0 1 1 1 0 DNA ligase 3 BRCT domain Astro_capsid_p PF12226.8 KFX88188.1 - 4.7 6.3 17.9 10 5.2 17.7 1.6 1 1 0 1 1 1 0 Turkey astrovirus capsid protein PIG-U PF06728.13 KFX88189.1 - 2.2e-124 415.4 29.0 2.5e-124 415.2 29.0 1.0 1 0 0 1 1 1 1 GPI transamidase subunit PIG-U PIRT PF15099.6 KFX88189.1 - 0.012 15.1 0.1 0.03 13.9 0.1 1.7 1 0 0 1 1 1 0 Phosphoinositide-interacting protein family 8TM_micro PF17028.5 KFX88189.1 - 0.036 13.8 9.7 0.083 12.6 9.7 1.5 1 0 0 1 1 1 0 8TM Microsporidial transmembrane domain DUF1708 PF08101.11 KFX88193.1 - 6.5e-175 582.4 0.0 8.9e-175 582.0 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1708) 2OG-FeII_Oxy_2 PF13532.6 KFX88196.1 - 6.4e-27 95.0 0.0 8.3e-27 94.6 0.0 1.1 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily zf-GRF PF06839.12 KFX88196.1 - 0.0031 17.6 4.7 0.0054 16.8 4.7 1.4 1 0 0 1 1 1 1 GRF zinc finger NicO PF03824.16 KFX88197.1 - 3.5e-48 164.4 3.8 4.1e-48 164.1 3.8 1.0 1 0 0 1 1 1 1 High-affinity nickel-transport protein YrvL PF14184.6 KFX88197.1 - 0.085 13.0 3.2 0.2 11.7 3.2 1.6 1 0 0 1 1 1 0 Regulatory protein YrvL zf-C2H2_3 PF13878.6 KFX88210.1 - 4.6e-10 39.2 0.2 7.9e-10 38.4 0.2 1.4 1 0 0 1 1 1 1 zinc-finger of acetyl-transferase ESCO polyprenyl_synt PF00348.17 KFX88211.1 - 6.5e-75 251.5 0.0 1.1e-74 250.7 0.0 1.4 1 1 0 1 1 1 1 Polyprenyl synthetase HEPPP_synt_1 PF07307.11 KFX88211.1 - 0.011 15.3 0.0 0.018 14.6 0.0 1.3 1 0 0 1 1 1 0 Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1 Pilus_CpaD PF09476.10 KFX88211.1 - 0.077 12.7 0.0 0.15 11.8 0.0 1.4 1 0 0 1 1 1 0 Pilus biogenesis CpaD protein (pilus_cpaD) Vma12 PF11712.8 KFX88212.1 - 5.8e-46 156.0 0.1 1.2e-45 155.0 0.1 1.5 1 0 0 1 1 1 1 Endoplasmic reticulum-based factor for assembly of V-ATPase DUF1772 PF08592.11 KFX88212.1 - 0.0098 16.2 0.9 0.017 15.4 0.9 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1772) MHYT PF03707.16 KFX88212.1 - 6.2 7.1 6.5 2.2 8.5 2.9 2.0 1 1 1 2 2 2 0 Bacterial signalling protein N terminal repeat JAB PF01398.21 KFX88214.1 - 8.3e-15 54.8 0.0 1.5e-14 54.0 0.0 1.3 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease USP8_dimer PF08969.11 KFX88214.1 - 5.4e-09 36.2 0.0 9.1e-09 35.5 0.0 1.3 1 0 0 1 1 1 1 USP8 dimerisation domain Prok-JAB PF14464.6 KFX88214.1 - 1.7e-05 24.6 0.0 5.8e-05 22.9 0.0 1.9 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain RrnaAD PF00398.20 KFX88215.1 - 0.0055 15.8 0.0 0.0076 15.3 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase FAST_1 PF06743.15 KFX88217.1 - 0.051 13.5 0.0 1.4 8.9 0.0 2.4 2 0 0 2 2 2 0 FAST kinase-like protein, subdomain 1 Sulfotransfer_3 PF13469.6 KFX88219.1 - 0.00051 20.5 0.0 1.3 9.3 0.0 2.9 3 1 0 3 3 3 2 Sulfotransferase family GLTT PF01744.20 KFX88219.1 - 0.0051 16.5 2.3 0.0051 16.5 2.3 2.6 2 1 0 2 2 2 1 GLTT repeat (6 copies) Ribonuc_red_lgC PF02867.15 KFX88220.1 - 1.2e-86 291.4 0.0 1.4e-86 291.1 0.0 1.1 1 0 0 1 1 1 1 Ribonucleotide reductase, barrel domain SET PF00856.28 KFX88221.1 - 4.3e-13 50.0 0.0 3e-11 44.0 0.0 2.2 1 1 0 1 1 1 1 SET domain DUF3723 PF12520.8 KFX88223.1 - 3.6e-14 52.3 0.0 3.6e-14 52.3 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF3723) SpoIIP PF07454.11 KFX88223.1 - 0.0019 17.7 11.1 0.0029 17.1 11.1 1.4 1 0 0 1 1 1 1 Stage II sporulation protein P (SpoIIP) Presenilin PF01080.17 KFX88223.1 - 0.0063 15.3 14.7 0.0075 15.1 14.7 1.2 1 0 0 1 1 1 1 Presenilin DDHD PF02862.17 KFX88223.1 - 0.017 15.3 6.4 0.027 14.6 6.4 1.4 1 0 0 1 1 1 0 DDHD domain Nop14 PF04147.12 KFX88223.1 - 0.026 12.7 24.8 0.03 12.5 24.8 1.1 1 0 0 1 1 1 0 Nop14-like family CobT PF06213.12 KFX88223.1 - 0.078 12.4 28.1 0.11 11.8 28.1 1.4 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Neur_chan_memb PF02932.16 KFX88223.1 - 0.089 12.8 5.4 0.12 12.5 5.4 1.4 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region SprA-related PF12118.8 KFX88223.1 - 0.16 11.1 24.1 0.24 10.5 24.1 1.2 1 0 0 1 1 1 0 SprA-related family SDA1 PF05285.12 KFX88223.1 - 0.19 11.1 29.4 0.25 10.7 29.4 1.1 1 0 0 1 1 1 0 SDA1 RR_TM4-6 PF06459.12 KFX88223.1 - 0.27 11.0 20.4 0.36 10.6 20.4 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 CCSAP PF15748.5 KFX88223.1 - 0.31 11.2 21.3 0.59 10.3 21.3 1.4 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated CDC45 PF02724.14 KFX88223.1 - 0.52 8.5 27.7 0.67 8.2 27.7 1.1 1 0 0 1 1 1 0 CDC45-like protein Zip PF02535.22 KFX88223.1 - 0.68 9.1 9.1 0.87 8.7 9.1 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter DUF913 PF06025.12 KFX88223.1 - 2.3 7.1 10.8 3 6.7 10.8 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) eIF-3_zeta PF05091.12 KFX88223.1 - 3.2 6.6 19.7 4.4 6.2 19.7 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Spt20 PF12090.8 KFX88223.1 - 3.3 7.3 24.7 5.5 6.5 24.7 1.4 1 0 0 1 1 1 0 Spt20 family XRN_M PF17846.1 KFX88223.1 - 3.4 6.5 12.5 4.5 6.1 12.5 1.3 1 0 0 1 1 1 0 Xrn1 helical domain TERB2 PF15101.6 KFX88223.1 - 5.2 7.1 14.0 9.4 6.2 14.0 1.5 1 0 0 1 1 1 0 Telomere-associated protein TERB2 SLC12 PF03522.15 KFX88223.1 - 6 5.8 18.2 8 5.4 18.2 1.1 1 0 0 1 1 1 0 Solute carrier family 12 Hid1 PF12722.7 KFX88223.1 - 6.9 4.7 19.0 8.6 4.3 19.0 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Sec62 PF03839.16 KFX88223.1 - 7.8 5.9 16.6 12 5.3 16.6 1.2 1 0 0 1 1 1 0 Translocation protein Sec62 GCFC PF07842.12 KFX88226.1 - 1.4e-78 264.3 3.9 1.4e-78 264.3 3.9 1.6 2 0 0 2 2 2 1 GC-rich sequence DNA-binding factor-like protein G-patch PF01585.23 KFX88226.1 - 5.8e-15 54.9 4.5 1.9e-14 53.2 4.5 2.0 1 0 0 1 1 1 1 G-patch domain TIP_N PF12457.8 KFX88226.1 - 2.6e-11 43.8 7.0 2.6e-11 43.8 7.0 2.8 2 1 0 2 2 2 1 Tuftelin interacting protein N terminal G-patch_2 PF12656.7 KFX88226.1 - 3.9e-07 30.0 3.0 3.9e-07 30.0 3.0 2.8 2 2 0 2 2 2 1 G-patch domain ATP-synt_E PF05680.12 KFX88226.1 - 7.2 7.0 8.9 0.7 10.3 1.8 2.6 2 0 0 2 2 2 0 ATP synthase E chain VASt PF16016.5 KFX88229.1 - 1.7e-33 116.2 0.2 3.7e-33 115.1 0.2 1.6 1 0 0 1 1 1 1 VAD1 Analog of StAR-related lipid transfer domain BAR_3 PF16746.5 KFX88229.1 - 1.5e-10 41.2 0.0 2.9e-10 40.2 0.0 1.4 1 0 0 1 1 1 1 BAR domain of APPL family PH PF00169.29 KFX88229.1 - 3.1e-08 34.1 0.1 1.5e-07 31.9 0.1 2.3 2 0 0 2 2 2 1 PH domain GRAM PF02893.20 KFX88229.1 - 0.0035 17.2 0.0 0.0078 16.1 0.0 1.5 1 0 0 1 1 1 1 GRAM domain Nitr_red_assoc PF09655.10 KFX88229.1 - 0.013 16.2 0.1 0.25 12.0 0.0 2.5 2 0 0 2 2 2 0 Conserved nitrate reductase-associated protein (Nitr_red_assoc) Eisosome1 PF12757.7 KFX88230.1 - 4.3e-30 104.5 7.8 4.3e-30 104.5 7.8 3.9 3 1 1 4 4 4 1 Eisosome protein 1 F-box PF00646.33 KFX88233.1 - 0.00015 21.5 0.0 0.00037 20.3 0.0 1.7 1 0 0 1 1 1 1 F-box domain APH PF01636.23 KFX88234.1 - 1.9e-05 24.7 0.2 0.00054 20.0 0.1 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.22 KFX88234.1 - 0.00011 21.8 0.0 0.00024 20.8 0.0 1.5 2 0 0 2 2 2 1 RIO1 family Kdo PF06293.14 KFX88234.1 - 0.00014 21.3 0.2 0.001 18.5 0.0 2.0 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family WaaY PF06176.11 KFX88234.1 - 0.00047 19.8 0.0 0.00071 19.2 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide core biosynthesis protein (WaaY) Pkinase PF00069.25 KFX88234.1 - 0.014 14.8 0.1 0.044 13.1 0.0 1.7 2 0 0 2 2 2 0 Protein kinase domain Cytochrom_D1 PF02239.16 KFX88234.1 - 0.014 13.9 0.0 0.022 13.3 0.0 1.4 1 0 0 1 1 1 0 Cytochrome D1 heme domain Seadorna_VP7 PF07387.11 KFX88234.1 - 0.036 13.1 0.0 0.059 12.4 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 Hydrolase_6 PF13344.6 KFX88235.1 - 1.6e-22 79.5 0.0 2.8e-22 78.7 0.0 1.4 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KFX88235.1 - 2e-13 50.2 0.0 1.6e-12 47.3 0.0 2.3 2 0 0 2 2 2 1 HAD-hyrolase-like Hydrolase PF00702.26 KFX88235.1 - 0.034 14.4 0.0 10 6.3 0.0 2.6 3 0 0 3 3 3 0 haloacid dehalogenase-like hydrolase DUF1794 PF08768.11 KFX88238.1 - 0.0091 15.9 0.1 0.053 13.5 0.1 1.8 1 1 0 1 1 1 1 Domain of unknown function (DUF1794) IDO PF01231.18 KFX88239.1 - 1.5e-35 122.8 0.0 1.9e-35 122.5 0.0 1.1 1 0 0 1 1 1 1 Indoleamine 2,3-dioxygenase Lactamase_B PF00753.27 KFX88240.1 - 1.1e-09 38.6 0.0 1.5e-09 38.2 0.0 1.2 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 KFX88240.1 - 0.0018 17.8 0.0 0.0024 17.4 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase superfamily domain PAP_assoc PF03828.19 KFX88243.1 - 3.3e-19 68.9 0.1 6.8e-19 67.8 0.1 1.6 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.23 KFX88243.1 - 1.1e-05 25.6 0.0 2.1e-05 24.7 0.0 1.4 1 0 0 1 1 1 1 Nucleotidyltransferase domain Polbeta PF18765.1 KFX88243.1 - 0.042 13.9 0.0 0.076 13.1 0.0 1.4 1 0 0 1 1 1 0 Polymerase beta, Nucleotidyltransferase EVC2_like PF12297.8 KFX88245.1 - 0.02 13.6 0.0 0.026 13.2 0.0 1.1 1 0 0 1 1 1 0 Ellis van Creveld protein 2 like protein LapA_dom PF06305.11 KFX88245.1 - 0.24 11.2 0.8 0.42 10.4 0.8 1.3 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain NUC153 PF08159.12 KFX88246.1 - 2e-12 46.7 1.3 3.8e-12 45.8 1.3 1.5 1 0 0 1 1 1 1 NUC153 domain WD40 PF00400.32 KFX88246.1 - 9.3e-08 32.6 0.3 0.0034 18.2 0.0 4.6 4 0 0 4 4 4 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFX88246.1 - 0.042 14.1 0.0 0.18 12.1 0.0 2.0 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 4 WD40 domain Noc2 PF03715.13 KFX88247.1 - 6.9e-125 416.2 0.0 1.7e-124 414.9 0.0 1.7 2 0 0 2 2 2 1 Noc2p family EST1_DNA_bind PF10373.9 KFX88247.1 - 0.0041 16.6 1.3 0.36 10.3 0.0 2.6 2 1 0 2 2 2 2 Est1 DNA/RNA binding domain Nop14 PF04147.12 KFX88247.1 - 0.0076 14.5 0.0 0.0076 14.5 0.0 3.8 3 1 1 4 4 4 2 Nop14-like family Calsarcin PF05556.11 KFX88247.1 - 0.011 15.3 2.4 0.024 14.2 2.4 1.5 1 0 0 1 1 1 0 Calcineurin-binding protein (Calsarcin) Hid1 PF12722.7 KFX88247.1 - 0.72 7.9 5.0 1 7.4 5.0 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein VPS28 PF03997.12 KFX88248.1 - 1e-70 237.3 0.2 1.2e-70 237.0 0.2 1.1 1 0 0 1 1 1 1 VPS28 protein MMM1 PF10296.9 KFX88249.1 - 6.2e-06 25.5 0.0 2e-05 23.8 0.0 1.7 2 0 0 2 2 2 1 Maintenance of mitochondrial morphology protein 1 XRN_M PF17846.1 KFX88264.1 - 0.26 10.2 9.8 0.3 10.0 9.8 1.1 1 0 0 1 1 1 0 Xrn1 helical domain TFIIF_alpha PF05793.12 KFX88264.1 - 0.76 8.3 37.3 0.97 8.0 37.3 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Cellulose_synt PF03552.14 KFX88264.1 - 5.6 5.3 5.0 7.2 5.0 5.0 1.2 1 0 0 1 1 1 0 Cellulose synthase GREB1 PF15782.5 KFX88264.1 - 6.7 3.7 14.8 7.4 3.6 14.8 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Thg1 PF04446.12 KFX88265.1 - 1.2e-52 177.2 0.0 2.8e-52 176.0 0.0 1.6 2 0 0 2 2 2 1 tRNAHis guanylyltransferase Thg1C PF14413.6 KFX88265.1 - 1.7e-50 170.2 0.2 2.3e-50 169.8 0.2 1.2 1 0 0 1 1 1 1 Thg1 C terminal domain AlaDh_PNT_N PF05222.15 KFX88266.1 - 2.8e-28 98.9 0.0 4.4e-28 98.3 0.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, N-terminal domain AlaDh_PNT_C PF01262.21 KFX88266.1 - 6.6e-05 22.3 0.0 0.00037 19.9 0.0 1.8 1 1 1 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain Utp11 PF03998.13 KFX88268.1 - 9.8e-61 205.8 22.5 1.1e-60 205.6 22.5 1.0 1 0 0 1 1 1 1 Utp11 protein SLATT_5 PF18160.1 KFX88268.1 - 0.084 12.2 0.0 0.18 11.1 0.0 1.5 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain family 5 Mt_ATP-synt_D PF05873.12 KFX88268.1 - 2 8.2 6.6 0.44 10.4 3.2 1.6 2 0 0 2 2 2 0 ATP synthase D chain, mitochondrial (ATP5H) KxDL PF10241.9 KFX88268.1 - 2.3 8.6 7.7 19 5.6 1.2 2.9 3 0 0 3 3 3 0 Uncharacterized conserved protein TMEM119 PF15724.5 KFX88268.1 - 9.4 6.2 6.1 15 5.6 6.1 1.2 1 0 0 1 1 1 0 TMEM119 family Cmc1 PF08583.10 KFX88269.1 - 1.6e-12 47.3 0.8 1.6e-12 47.3 0.8 1.8 1 1 1 2 2 2 1 Cytochrome c oxidase biogenesis protein Cmc1 like Helo_like_N PF17111.5 KFX88270.1 - 0.5 9.7 1.9 4.2 6.7 0.1 2.3 2 0 0 2 2 2 0 Fungal N-terminal domain of STAND proteins tRNA-synt_2b PF00587.25 KFX88271.1 - 3.1e-31 108.7 0.0 3.3e-27 95.6 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 KFX88271.1 - 0.00057 20.0 0.0 0.00098 19.2 0.0 1.4 1 0 0 1 1 1 1 Anticodon binding domain ADH_N_2 PF16884.5 KFX88272.1 - 2.6e-23 82.0 0.0 4.7e-23 81.1 0.0 1.4 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase ADH_zinc_N PF00107.26 KFX88272.1 - 5.8e-18 65.1 0.0 9.7e-18 64.4 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KFX88272.1 - 1e-05 26.6 0.0 1.9e-05 25.7 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase DUF2855 PF11017.8 KFX88272.1 - 0.046 13.5 0.1 0.61 9.8 0.0 2.3 2 1 1 3 3 3 0 Protein of unknown function (DUF2855) HLH PF00010.26 KFX88273.1 - 1.8e-09 37.4 0.0 4.1e-09 36.3 0.0 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Umbravirus_LDM PF04817.12 KFX88273.1 - 0.0069 15.8 0.5 0.0087 15.4 0.5 1.1 1 0 0 1 1 1 1 Umbravirus long distance movement (LDM) family ABC_membrane PF00664.23 KFX88275.1 - 5.6e-88 295.1 24.5 6.5e-50 170.3 7.7 2.5 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 KFX88275.1 - 2.2e-49 167.5 0.0 1.1e-28 100.4 0.1 2.8 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 KFX88275.1 - 4.5e-09 36.1 4.3 0.016 14.6 0.0 4.2 2 2 2 4 4 4 2 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 KFX88275.1 - 1.1e-05 25.4 0.2 0.16 12.0 0.0 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_16 PF13191.6 KFX88275.1 - 0.00016 22.1 2.0 0.012 16.1 0.5 2.8 3 0 0 3 3 2 1 AAA ATPase domain RsgA_GTPase PF03193.16 KFX88275.1 - 0.00041 20.3 0.0 0.22 11.4 0.0 2.5 2 0 0 2 2 2 1 RsgA GTPase AAA_29 PF13555.6 KFX88275.1 - 0.00048 19.8 0.5 1.7 8.4 0.0 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain Dynamin_N PF00350.23 KFX88275.1 - 0.0012 18.9 0.8 0.13 12.3 0.0 2.6 2 0 0 2 2 2 1 Dynamin family AAA_23 PF13476.6 KFX88275.1 - 0.0028 18.2 0.2 0.34 11.4 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_15 PF13175.6 KFX88275.1 - 0.01 15.6 0.0 0.83 9.3 0.0 2.4 2 0 0 2 2 2 0 AAA ATPase domain AAA_21 PF13304.6 KFX88275.1 - 0.011 15.6 1.6 1 9.1 0.1 2.9 3 0 0 3 3 3 0 AAA domain, putative AbiEii toxin, Type IV TA system T2SSE PF00437.20 KFX88275.1 - 0.019 14.0 0.0 0.3 10.1 0.0 2.4 2 0 0 2 2 2 0 Type II/IV secretion system protein ATP_bind_1 PF03029.17 KFX88275.1 - 0.049 13.4 1.1 12 5.6 0.0 3.1 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein DUF87 PF01935.17 KFX88275.1 - 0.055 13.5 5.8 2.1 8.4 0.1 3.0 3 0 0 3 3 3 0 Helicase HerA, central domain Roc PF08477.13 KFX88275.1 - 0.059 13.6 0.1 15 5.8 0.0 3.2 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase FtsK_SpoIIIE PF01580.18 KFX88275.1 - 0.074 12.4 0.3 4.6 6.5 0.1 2.4 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_30 PF13604.6 KFX88275.1 - 0.12 12.0 1.3 12 5.6 0.0 3.0 2 1 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 KFX88275.1 - 0.13 12.7 0.0 9 6.7 0.0 2.7 2 0 0 2 2 2 0 RNA helicase NACHT PF05729.12 KFX88275.1 - 0.15 12.0 0.3 1 9.3 0.0 2.4 2 0 0 2 2 2 0 NACHT domain CDC45 PF02724.14 KFX88275.1 - 0.18 10.0 1.4 0.27 9.5 1.4 1.1 1 0 0 1 1 1 0 CDC45-like protein AAA_22 PF13401.6 KFX88275.1 - 0.44 10.8 2.6 45 4.3 0.3 3.3 2 1 0 2 2 2 0 AAA domain AIG1 PF04548.16 KFX88275.1 - 0.55 9.5 2.0 7.4 5.8 0.1 2.5 2 0 0 2 2 2 0 AIG1 family 60KD_IMP PF02096.20 KFX88275.1 - 6.8 6.6 11.9 0.5 10.3 5.8 2.2 2 0 0 2 2 2 0 60Kd inner membrane protein HLH PF00010.26 KFX88276.1 - 3.5e-12 46.1 0.3 7.8e-12 45.0 0.3 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Herpes_UL6 PF01763.16 KFX88276.1 - 0.034 12.7 1.3 0.053 12.0 1.3 1.2 1 0 0 1 1 1 0 Herpesvirus UL6 like GIT1_C PF12205.8 KFX88276.1 - 0.1 12.7 0.9 0.65 10.1 0.9 2.2 1 1 0 1 1 1 0 G protein-coupled receptor kinase-interacting protein 1 C term DUF3450 PF11932.8 KFX88276.1 - 4.7 6.5 10.3 0.65 9.3 0.5 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) CLTH PF10607.9 KFX88277.1 - 8.4e-35 119.8 0.0 1.7e-34 118.9 0.0 1.5 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain LisH PF08513.11 KFX88277.1 - 0.0046 16.9 0.0 0.014 15.3 0.0 1.9 1 0 0 1 1 1 1 LisH IL28A PF15177.6 KFX88277.1 - 0.023 14.5 1.5 0.041 13.7 1.5 1.3 1 0 0 1 1 1 0 Interleukin-28A NDUF_B12 PF08122.12 KFX88278.1 - 8.9e-26 89.7 0.7 1.5e-25 89.0 0.7 1.3 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B12 subunit family DUF4452 PF14618.6 KFX88279.1 - 5.4e-59 198.9 12.6 5.9e-59 198.7 12.6 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4452) Aminotran_3 PF00202.21 KFX88289.1 - 2.2e-37 128.7 0.0 7.5e-26 90.7 0.1 2.2 2 0 0 2 2 2 2 Aminotransferase class-III Raftlin PF15250.6 KFX88289.1 - 3.4 6.3 19.2 0.018 13.8 8.8 2.1 2 0 0 2 2 2 0 Raftlin Aldedh PF00171.22 KFX88297.1 - 6.3e-186 618.4 0.5 7.2e-186 618.2 0.5 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Tim17 PF02466.19 KFX88301.1 - 1.1e-08 35.4 2.1 1.1e-08 35.4 2.1 1.8 1 1 1 2 2 2 1 Tim17/Tim22/Tim23/Pmp24 family Pribosyltran PF00156.27 KFX88302.1 - 7.5e-15 54.8 0.0 1.3e-14 54.1 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosyl transferase domain Glyco_hydro_127 PF07944.12 KFX88303.1 - 7e-141 470.3 1.4 8e-141 470.1 1.4 1.0 1 0 0 1 1 1 1 Beta-L-arabinofuranosidase, GH127 DUF4986 PF16375.5 KFX88303.1 - 0.067 13.9 0.0 0.16 12.6 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function Ank_2 PF12796.7 KFX88304.1 - 2.3e-53 178.7 0.2 1.9e-16 60.4 0.0 4.6 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KFX88304.1 - 9.2e-37 120.9 3.4 0.00015 21.9 0.0 10.2 8 2 2 10 10 10 8 Ankyrin repeat Ank_4 PF13637.6 KFX88304.1 - 9.1e-34 115.4 0.1 3.7e-06 27.4 0.0 6.7 3 2 4 7 7 7 6 Ankyrin repeats (many copies) Ank PF00023.30 KFX88304.1 - 1.2e-31 107.7 5.3 3.7e-07 30.3 0.0 9.1 8 2 0 8 8 8 6 Ankyrin repeat Ank_5 PF13857.6 KFX88304.1 - 2e-24 85.3 2.4 1.7e-05 25.0 0.0 8.1 2 2 7 9 9 9 7 Ankyrin repeats (many copies) MFS_1 PF07690.16 KFX88306.1 - 5e-45 154.0 49.6 1.4e-44 152.5 48.2 2.3 2 1 0 2 2 2 1 Major Facilitator Superfamily Phage_holin_5_1 PF06946.11 KFX88306.1 - 2.1 8.8 7.1 0.38 11.2 0.2 3.1 3 0 0 3 3 3 0 Bacteriophage A118-like holin, Hol118 HRI1 PF16815.5 KFX88308.1 - 1.5e-30 106.6 0.0 1.7e-30 106.5 0.0 1.0 1 0 0 1 1 1 1 Protein HRI1 Abdominal-A PF12407.8 KFX88309.1 - 0.092 12.3 2.1 0.19 11.3 2.1 1.5 1 0 0 1 1 1 0 Homeobox protein Sugar_tr PF00083.24 KFX88313.1 - 5.2e-119 398.1 28.4 6.3e-119 397.8 28.4 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KFX88313.1 - 1.4e-18 67.0 41.1 5.7e-13 48.5 23.3 2.6 1 1 1 2 2 2 2 Major Facilitator Superfamily Phage_holin_3_2 PF04550.12 KFX88313.1 - 0.36 11.4 5.3 1.2 9.7 5.3 1.9 1 0 0 1 1 1 0 Phage holin family 2 DUF2530 PF10745.9 KFX88313.1 - 0.98 9.7 6.2 2.4 8.5 4.0 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2530) PhyH PF05721.13 KFX88318.1 - 3.4e-12 47.1 0.0 5.7e-12 46.3 0.0 1.3 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) MutS_V PF00488.21 KFX88334.1 - 6.9e-48 163.2 0.0 1.3e-47 162.3 0.0 1.4 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 KFX88334.1 - 1.3e-20 74.4 0.1 3.8e-20 72.9 0.0 1.9 2 0 0 2 2 2 1 MutS domain III zf-primase PF09329.11 KFX88335.1 - 1.1e-20 73.1 1.6 2.1e-20 72.3 1.6 1.5 1 0 0 1 1 1 1 Primase zinc finger RNase_H2-Ydr279 PF09468.10 KFX88336.1 - 1.6e-42 145.4 0.0 4.1e-42 144.1 0.0 1.7 1 0 0 1 1 1 1 Ydr279p protein family (RNase H2 complex component) wHTH domain Ydr279_N PF17745.1 KFX88336.1 - 8.5e-25 86.8 0.0 2e-24 85.6 0.0 1.7 1 0 0 1 1 1 1 Ydr279p protein triple barrel domain Ntox15 PF15604.6 KFX88336.1 - 0.13 12.4 2.9 0.21 11.7 2.9 1.3 1 0 0 1 1 1 0 Novel toxin 15 DYW_deaminase PF14432.6 KFX88338.1 - 0.066 13.1 0.0 0.066 13.1 0.0 1.0 1 0 0 1 1 1 0 DYW family of nucleic acid deaminases zf-rbx1 PF12678.7 KFX88339.1 - 3.5e-09 36.8 12.2 5.1e-08 33.1 2.5 2.9 3 0 0 3 3 2 2 RING-H2 zinc finger domain PHD PF00628.29 KFX88339.1 - 5e-09 35.9 8.2 5e-09 35.9 8.2 2.6 2 0 0 2 2 2 1 PHD-finger zf-RING_2 PF13639.6 KFX88339.1 - 5.1e-08 33.1 2.9 5.1e-08 33.1 2.9 4.0 3 1 0 3 3 3 1 Ring finger domain Prok-RING_4 PF14447.6 KFX88339.1 - 9.3e-07 28.6 2.3 9.3e-07 28.6 2.3 3.5 3 0 0 3 3 3 1 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.6 KFX88339.1 - 2.8e-05 23.9 1.9 2.8e-05 23.9 1.9 4.1 3 1 1 4 4 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KFX88339.1 - 3.4e-05 23.6 0.9 3.4e-05 23.6 0.9 3.9 3 1 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 KFX88339.1 - 3.6e-05 23.7 2.0 3.6e-05 23.7 2.0 2.4 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_5 PF14634.6 KFX88339.1 - 5.2e-05 23.1 3.6 5.2e-05 23.1 3.6 3.5 4 0 0 4 4 3 1 zinc-RING finger domain Zn_ribbon_17 PF17120.5 KFX88339.1 - 5.4e-05 22.7 2.5 5.4e-05 22.7 2.5 2.9 2 1 1 3 3 3 1 Zinc-ribbon, C4HC2 type zf-C3HC4 PF00097.25 KFX88339.1 - 0.00028 20.7 4.1 0.00028 20.7 4.1 3.6 2 2 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) Rtf2 PF04641.12 KFX88339.1 - 0.00031 20.2 1.7 0.00061 19.2 0.1 2.3 2 0 0 2 2 2 1 Rtf2 RING-finger Prok-RING_1 PF14446.6 KFX88339.1 - 0.006 16.5 2.6 0.006 16.5 2.6 3.5 4 0 0 4 4 4 1 Prokaryotic RING finger family 1 zf-PHD-like PF15446.6 KFX88339.1 - 0.28 10.8 0.1 0.28 10.8 0.1 3.4 3 1 1 4 4 4 0 PHD/FYVE-zinc-finger like domain zf-RING_UBOX PF13445.6 KFX88339.1 - 0.38 10.8 20.4 0.45 10.6 1.2 4.8 3 2 0 3 3 3 0 RING-type zinc-finger FANCL_C PF11793.8 KFX88339.1 - 0.43 10.8 9.9 0.14 12.4 2.0 2.6 2 1 0 2 2 2 0 FANCL C-terminal domain zinc_ribbon_16 PF17034.5 KFX88339.1 - 0.88 9.8 5.4 0.26 11.5 0.4 2.4 2 0 0 2 2 2 0 Zinc-ribbon like family PHD_2 PF13831.6 KFX88339.1 - 1.3 8.6 12.1 0.019 14.5 3.6 2.2 2 0 0 2 2 2 0 PHD-finger Pellino PF04710.14 KFX88339.1 - 1.5 7.4 4.7 0.75 8.4 0.7 2.0 1 1 1 2 2 2 0 Pellino zf-RING-like PF08746.11 KFX88339.1 - 2.1 8.7 12.3 0.067 13.5 1.8 2.6 2 0 0 2 2 2 0 RING-like domain Prim_Zn_Ribbon PF08273.12 KFX88339.1 - 4.9 7.5 8.5 2.1 8.7 0.2 3.0 3 0 0 3 3 3 0 Zinc-binding domain of primase-helicase Ribosomal_L37ae PF01780.19 KFX88340.1 - 3.4e-40 136.0 9.3 3.8e-40 135.8 9.3 1.0 1 0 0 1 1 1 1 Ribosomal L37ae protein family Zn_Tnp_IS1595 PF12760.7 KFX88340.1 - 0.0013 18.7 3.0 0.0021 18.0 3.0 1.3 1 0 0 1 1 1 1 Transposase zinc-ribbon domain DUF1451 PF07295.11 KFX88340.1 - 0.0029 17.7 0.8 0.004 17.2 0.8 1.2 1 0 0 1 1 1 1 Zinc-ribbon containing domain zf-RING_13 PF17977.1 KFX88340.1 - 0.0035 17.5 1.7 0.0049 17.0 1.7 1.2 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-BED PF02892.15 KFX88340.1 - 0.018 15.1 4.4 0.1 12.6 0.4 2.2 1 1 1 2 2 2 0 BED zinc finger Sgf11 PF08209.11 KFX88340.1 - 0.047 13.3 0.3 0.46 10.1 0.0 2.2 2 0 0 2 2 2 0 Sgf11 (transcriptional regulation protein) Zn-ribbon_8 PF09723.10 KFX88340.1 - 0.047 13.8 0.6 0.099 12.8 0.6 1.5 1 0 0 1 1 1 0 Zinc ribbon domain A2L_zn_ribbon PF08792.10 KFX88340.1 - 0.16 11.7 1.6 0.37 10.6 0.0 2.0 2 0 0 2 2 2 0 A2L zinc ribbon domain Zn_ribbon_SprT PF17283.2 KFX88340.1 - 0.19 11.6 4.3 0.22 11.4 3.1 1.7 1 1 1 2 2 2 0 SprT-like zinc ribbon domain CarbpepA_inh PF02977.15 KFX88340.1 - 0.25 11.1 0.3 0.25 11.1 0.3 2.1 1 1 1 2 2 2 0 Carboxypeptidase A inhibitor zf-H2C2_2 PF13465.6 KFX88340.1 - 0.61 10.6 6.1 1 9.9 0.5 2.3 1 1 1 2 2 2 0 Zinc-finger double domain Sacchrp_dh_NADP PF03435.18 KFX88341.1 - 3.3e-14 53.3 0.0 5e-14 52.7 0.0 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain DUF423 PF04241.15 KFX88345.1 - 0.0077 16.4 0.6 0.0077 16.4 0.6 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF423) SKG6 PF08693.10 KFX88353.1 - 0.028 13.8 2.1 0.065 12.7 2.1 1.7 1 0 0 1 1 1 0 Transmembrane alpha-helix domain VSP PF03302.13 KFX88353.1 - 0.17 10.7 0.8 0.27 10.0 0.8 1.2 1 0 0 1 1 1 0 Giardia variant-specific surface protein T2SSE PF00437.20 KFX88374.1 - 0.0032 16.6 0.0 0.0061 15.7 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_18 PF13238.6 KFX88374.1 - 0.014 15.9 1.5 0.15 12.6 0.0 2.9 3 0 0 3 3 3 0 AAA domain AAA_21 PF13304.6 KFX88374.1 - 0.087 12.6 2.2 0.58 9.9 0.2 2.7 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system PRK PF00485.18 KFX88374.1 - 0.1 12.3 0.0 0.19 11.5 0.0 1.4 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family MobB PF03205.14 KFX88374.1 - 0.15 12.0 0.1 0.4 10.6 0.0 1.7 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B ABC_tran PF00005.27 KFX88374.1 - 0.17 12.4 0.1 1.1 9.7 0.1 2.2 2 0 0 2 2 2 0 ABC transporter Dak1 PF02733.17 KFX88375.1 - 0.029 13.3 0.2 0.058 12.3 0.2 1.5 1 0 0 1 1 1 0 Dak1 domain DUF1843 PF08898.10 KFX88375.1 - 0.055 14.0 3.5 3.4 8.3 0.1 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF1843) HALZ PF02183.18 KFX88375.1 - 0.055 13.7 8.0 14 6.0 0.2 3.8 2 1 1 3 3 3 0 Homeobox associated leucine zipper JIP_LZII PF16471.5 KFX88375.1 - 1 9.6 13.1 0.62 10.3 0.2 3.1 3 0 0 3 3 3 0 JNK-interacting protein leucine zipper II APG6_N PF17675.1 KFX88375.1 - 3.8 8.1 24.0 11 6.6 14.2 2.5 2 1 0 2 2 2 0 Apg6 coiled-coil region FtsL PF04999.13 KFX88375.1 - 4.3 7.4 12.2 1.3 9.0 0.2 3.5 3 1 1 4 4 4 0 Cell division protein FtsL Rrp15p PF07890.12 KFX88378.1 - 3.2e-38 131.1 12.7 3.2e-38 131.1 12.7 1.9 2 1 0 2 2 2 1 Rrp15p DUF1131 PF06572.12 KFX88378.1 - 0.076 12.7 1.6 0.12 12.1 1.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1131) SRP54 PF00448.22 KFX88379.1 - 5.4e-76 254.6 1.9 7.4e-76 254.2 1.1 1.6 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain SRP_SPB PF02978.19 KFX88379.1 - 9.9e-31 106.3 3.9 9.9e-31 106.3 3.9 4.2 3 2 1 4 4 3 1 Signal peptide binding domain SRP54_N PF02881.19 KFX88379.1 - 1.8e-20 72.9 1.1 5.4e-20 71.4 1.1 1.9 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain cobW PF02492.19 KFX88379.1 - 1.9e-06 27.6 0.8 1.4e-05 24.8 0.9 2.3 2 1 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_33 PF13671.6 KFX88379.1 - 3.2e-06 27.3 0.0 6.6e-06 26.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.6 KFX88379.1 - 3.5e-06 27.5 0.1 1.4e-05 25.5 0.1 2.1 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 KFX88379.1 - 3.2e-05 23.3 0.0 3.2e-05 23.3 0.0 2.0 2 0 0 2 2 1 1 Zeta toxin AAA_16 PF13191.6 KFX88379.1 - 7.6e-05 23.1 0.0 0.00014 22.2 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain APS_kinase PF01583.20 KFX88379.1 - 0.0013 18.6 0.0 0.003 17.5 0.0 1.6 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_30 PF13604.6 KFX88379.1 - 0.0022 17.8 0.0 0.007 16.1 0.0 1.9 1 0 0 1 1 1 1 AAA domain ResIII PF04851.15 KFX88379.1 - 0.0034 17.4 0.3 0.0093 16.0 0.3 1.7 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit SRPRB PF09439.10 KFX88379.1 - 0.0041 16.6 1.4 2.2 7.7 1.7 3.1 2 1 0 2 2 2 1 Signal recognition particle receptor beta subunit Thymidylate_kin PF02223.17 KFX88379.1 - 0.0043 16.8 0.4 0.016 14.9 0.0 2.2 3 0 0 3 3 2 1 Thymidylate kinase MMR_HSR1 PF01926.23 KFX88379.1 - 0.0051 16.9 0.4 0.022 14.8 0.2 2.2 2 1 0 2 2 1 1 50S ribosome-binding GTPase CbiA PF01656.23 KFX88379.1 - 0.0052 16.8 0.0 0.015 15.4 0.0 1.8 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_18 PF13238.6 KFX88379.1 - 0.0058 17.2 0.0 0.013 16.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain ATP_bind_1 PF03029.17 KFX88379.1 - 0.0069 16.2 0.7 0.033 14.0 0.1 2.3 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein AAA_22 PF13401.6 KFX88379.1 - 0.011 16.0 0.1 0.029 14.7 0.1 1.8 1 1 0 1 1 1 0 AAA domain AAA_28 PF13521.6 KFX88379.1 - 0.019 15.2 0.1 0.034 14.4 0.1 1.5 1 1 0 1 1 1 0 AAA domain MobB PF03205.14 KFX88379.1 - 0.02 14.8 0.0 0.055 13.4 0.0 1.8 2 0 0 2 2 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA PF00004.29 KFX88379.1 - 0.033 14.6 0.2 0.092 13.2 0.2 1.9 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) 6PF2K PF01591.18 KFX88379.1 - 0.034 13.5 0.0 0.054 12.8 0.0 1.4 1 0 0 1 1 1 0 6-phosphofructo-2-kinase AAA_19 PF13245.6 KFX88379.1 - 0.035 14.4 0.0 0.092 13.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain Torsin PF06309.11 KFX88379.1 - 0.037 14.1 0.0 0.078 13.1 0.0 1.5 1 0 0 1 1 1 0 Torsin AAA_31 PF13614.6 KFX88379.1 - 0.089 12.7 0.1 0.3 11.0 0.1 1.9 1 1 0 1 1 1 0 AAA domain SKA2 PF16740.5 KFX88379.1 - 0.51 10.1 2.4 14 5.5 0.0 2.7 2 0 0 2 2 2 0 Spindle and kinetochore-associated protein 2 GET2 PF08690.10 KFX88379.1 - 2.5 7.7 7.1 1.1 8.8 4.3 2.0 1 1 0 1 1 1 0 GET complex subunit GET2 Cmc1 PF08583.10 KFX88381.1 - 0.0067 16.4 1.2 0.015 15.3 1.2 1.6 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like CwsA PF10814.8 KFX88381.1 - 0.14 12.3 0.1 0.29 11.3 0.1 1.5 1 0 0 1 1 1 0 Cell wall synthesis protein CwsA Aldose_epim PF01263.20 KFX88382.1 - 1.2e-33 116.7 0.0 1.5e-33 116.4 0.0 1.1 1 0 0 1 1 1 1 Aldose 1-epimerase IQCJ-SCHIP1 PF15157.6 KFX88382.1 - 0.093 12.6 0.8 0.19 11.6 0.6 1.5 2 0 0 2 2 2 0 Fusion protein IQCJ-SCHIP1 with IQ-like motif CDH-cyt PF16010.5 KFX88385.1 - 2.6e-12 46.8 0.3 6.1e-12 45.6 0.3 1.5 1 1 0 1 1 1 1 Cytochrome domain of cellobiose dehydrogenase DUF2427 PF10348.9 KFX88385.1 - 3.5e-06 26.7 2.0 6.8e-06 25.8 2.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF2427) Cytochrom_B561 PF03188.16 KFX88385.1 - 3.9e-05 23.8 8.3 3.9e-05 23.8 8.3 1.7 2 0 0 2 2 2 1 Eukaryotic cytochrome b561 DOMON PF03351.17 KFX88385.1 - 0.00018 21.7 0.1 0.00033 20.9 0.1 1.4 1 0 0 1 1 1 1 DOMON domain OAD_gamma PF04277.13 KFX88391.1 - 0.0099 16.4 0.0 0.12 13.0 0.0 2.1 2 0 0 2 2 2 1 Oxaloacetate decarboxylase, gamma chain SET PF00856.28 KFX88396.1 - 1.2e-09 38.8 0.1 4.4e-09 37.0 0.0 2.0 2 0 0 2 2 2 1 SET domain Trypan_PARP PF05887.11 KFX88396.1 - 0.012 15.6 14.5 0.022 14.8 14.5 1.4 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Rib_recp_KP_reg PF05104.12 KFX88396.1 - 0.47 11.5 9.6 0.87 10.6 9.6 1.4 1 0 0 1 1 1 0 Ribosome receptor lysine/proline rich region ATP_bind_1 PF03029.17 KFX88398.1 - 5.1e-71 239.3 0.0 6.1e-71 239.0 0.0 1.0 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein AAA_14 PF13173.6 KFX88398.1 - 0.00048 20.2 0.0 0.00097 19.2 0.0 1.6 1 1 0 1 1 1 1 AAA domain CLP1_P PF16575.5 KFX88398.1 - 0.0014 18.5 0.0 0.0044 16.8 0.0 1.8 2 0 0 2 2 2 1 mRNA cleavage and polyadenylation factor CLP1 P-loop AAA_24 PF13479.6 KFX88398.1 - 0.003 17.3 0.0 0.0044 16.8 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 KFX88398.1 - 0.004 17.7 0.0 0.0082 16.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 KFX88398.1 - 0.0044 17.4 0.0 0.0081 16.5 0.0 1.4 1 0 0 1 1 1 1 RNA helicase AAA_22 PF13401.6 KFX88398.1 - 0.01 16.1 0.0 0.017 15.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain GTP_EFTU PF00009.27 KFX88398.1 - 0.01 15.4 0.0 1.7 8.1 0.0 2.5 3 0 0 3 3 3 0 Elongation factor Tu GTP binding domain AAA_7 PF12775.7 KFX88398.1 - 0.011 15.2 0.0 0.017 14.7 0.0 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region KAP_NTPase PF07693.14 KFX88398.1 - 0.022 14.0 0.0 0.036 13.3 0.0 1.3 1 1 0 1 1 1 0 KAP family P-loop domain NACHT PF05729.12 KFX88398.1 - 0.025 14.5 0.0 0.039 13.9 0.0 1.3 1 0 0 1 1 1 0 NACHT domain AAA PF00004.29 KFX88398.1 - 0.025 15.0 0.0 0.042 14.3 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KFX88398.1 - 0.025 15.0 0.0 0.079 13.3 0.0 1.7 2 0 0 2 2 2 0 AAA ATPase domain cobW PF02492.19 KFX88398.1 - 0.031 13.9 0.0 0.77 9.3 0.0 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain TsaE PF02367.17 KFX88398.1 - 0.033 14.2 0.0 0.058 13.4 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE SRP54 PF00448.22 KFX88398.1 - 0.037 13.6 0.0 0.062 12.9 0.0 1.3 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain ArsA_ATPase PF02374.15 KFX88398.1 - 0.05 12.8 0.0 0.083 12.1 0.0 1.3 1 0 0 1 1 1 0 Anion-transporting ATPase AAA_30 PF13604.6 KFX88398.1 - 0.05 13.3 0.0 0.17 11.6 0.0 1.8 2 0 0 2 2 2 0 AAA domain DUF463 PF04317.12 KFX88398.1 - 0.054 12.4 0.0 0.088 11.7 0.0 1.2 1 0 0 1 1 1 0 YcjX-like family, DUF463 NTPase_1 PF03266.15 KFX88398.1 - 0.058 13.3 0.0 0.6 10.0 0.0 2.1 2 0 0 2 2 2 0 NTPase CbiA PF01656.23 KFX88398.1 - 0.059 13.4 0.0 0.079 13.0 0.0 1.4 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_33 PF13671.6 KFX88398.1 - 0.069 13.3 0.0 0.11 12.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain T2SSE PF00437.20 KFX88398.1 - 0.079 12.0 0.0 0.11 11.5 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein Septin PF00735.18 KFX88398.1 - 0.081 12.2 0.0 0.13 11.5 0.0 1.2 1 0 0 1 1 1 0 Septin ATPase_2 PF01637.18 KFX88398.1 - 0.082 12.8 0.0 0.12 12.3 0.0 1.2 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_19 PF13245.6 KFX88398.1 - 0.097 13.0 0.0 0.32 11.3 0.0 1.8 2 0 0 2 2 1 0 AAA domain AAA_25 PF13481.6 KFX88398.1 - 0.11 12.1 0.0 0.38 10.3 0.0 1.8 2 0 0 2 2 2 0 AAA domain DUF447 PF04289.12 KFX88398.1 - 0.16 11.7 0.0 0.28 11.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF447) PduV-EutP PF10662.9 KFX88398.1 - 0.18 11.5 0.0 0.72 9.6 0.0 2.0 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation S-AdoMet_synt_C PF02773.16 KFX88399.1 - 3.9e-67 224.5 0.4 1.1e-66 223.1 0.0 1.8 2 0 0 2 2 2 1 S-adenosylmethionine synthetase, C-terminal domain S-AdoMet_synt_M PF02772.16 KFX88399.1 - 3.3e-45 153.2 0.0 6.2e-45 152.3 0.0 1.5 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, central domain S-AdoMet_synt_N PF00438.20 KFX88399.1 - 2.8e-43 146.6 0.5 7.2e-43 145.3 0.1 1.9 2 0 0 2 2 2 1 S-adenosylmethionine synthetase, N-terminal domain DEAD PF00270.29 KFX88424.1 - 1.9e-50 171.1 0.0 1.8e-49 167.9 0.0 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KFX88424.1 - 1.1e-26 93.3 0.0 5.7e-26 91.0 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KFX88424.1 - 0.00028 20.9 0.0 0.0076 16.3 0.0 2.9 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit Aa_trans PF01490.18 KFX88425.1 - 1.6e-28 99.6 37.2 2e-28 99.2 37.2 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein SNF2_N PF00176.23 KFX88434.1 - 4.6e-65 219.6 0.3 7.7e-65 218.9 0.3 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KFX88434.1 - 4.2e-19 68.9 0.0 3.7e-18 65.9 0.1 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KFX88434.1 - 2.4e-10 40.7 2.6 2.6e-10 40.6 0.0 2.4 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit HSA PF07529.13 KFX88434.1 - 0.00034 20.9 8.1 0.00034 20.9 8.1 3.3 1 1 2 3 3 3 1 HSA DEAD PF00270.29 KFX88434.1 - 0.00088 19.1 0.0 0.0022 17.8 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase DEAD_2 PF06733.15 KFX88434.1 - 0.1 12.2 1.6 0.18 11.4 0.0 2.2 3 0 0 3 3 3 0 DEAD_2 AAA_25 PF13481.6 KFX88434.1 - 0.4 10.2 4.3 2.6 7.6 0.0 3.2 3 0 0 3 3 3 0 AAA domain Phage_holin_3_5 PF16085.5 KFX88435.1 - 0.0059 16.7 0.0 0.0064 16.6 0.0 1.0 1 0 0 1 1 1 1 Bacteriophage holin Hol, superfamily III zf-CCCH PF00642.24 KFX88436.1 - 5.5e-10 38.9 9.2 6.6e-05 22.7 2.6 2.6 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 KFX88436.1 - 1.2e-09 37.7 12.1 3.2e-05 23.6 3.7 2.7 2 0 0 2 2 2 2 CCCH-type zinc finger Torus PF16131.5 KFX88436.1 - 4.2e-09 37.1 6.7 0.00012 22.7 0.5 2.5 1 1 1 2 2 2 2 Torus domain zf_CCCH_4 PF18345.1 KFX88436.1 - 6.4e-08 32.4 22.8 0.00015 21.7 5.3 2.7 3 0 0 3 3 3 2 Zinc finger domain zf-CCCH_3 PF15663.5 KFX88436.1 - 0.001 19.2 2.5 0.0022 18.2 2.5 1.5 1 0 0 1 1 1 1 Zinc-finger containing family zf-CCCH_2 PF14608.6 KFX88436.1 - 0.34 11.5 24.9 0.2 12.2 3.8 3.3 3 0 0 3 3 3 0 RNA-binding, Nab2-type zinc finger HD-ZIP_N PF04618.12 KFX88436.1 - 2 8.9 7.1 7.6 7.1 0.4 2.7 2 0 0 2 2 2 0 HD-ZIP protein N terminus Frag1 PF10277.9 KFX88443.1 - 2.2e-41 141.8 9.7 3.2e-41 141.3 9.7 1.3 1 0 0 1 1 1 1 Frag1/DRAM/Sfk1 family U3_assoc_6 PF08640.11 KFX88444.1 - 1.3e-26 92.5 0.1 9.9e-25 86.4 0.0 2.3 2 0 0 2 2 2 1 U3 small nucleolar RNA-associated protein 6 Cytomega_US3 PF05963.11 KFX88444.1 - 0.099 12.3 0.0 0.28 10.8 0.0 1.7 1 1 0 1 1 1 0 Cytomegalovirus US3 protein NRDE-2 PF08424.10 KFX88444.1 - 0.15 11.2 0.0 0.22 10.6 0.0 1.3 1 0 0 1 1 1 0 NRDE-2, necessary for RNA interference TRI12 PF06609.13 KFX88447.1 - 3.8e-41 141.2 29.8 4.7e-41 140.9 29.8 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.16 KFX88447.1 - 9.8e-22 77.3 58.1 9.8e-22 77.3 58.1 2.7 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KFX88447.1 - 4.3e-10 39.1 11.6 4.3e-10 39.1 11.6 2.7 3 0 0 3 3 3 2 Sugar (and other) transporter Tymo_coat PF00983.18 KFX88447.1 - 0.078 12.8 0.0 0.18 11.6 0.0 1.5 1 0 0 1 1 1 0 Tymovirus coat protein IMD PF08397.11 KFX88448.1 - 0.03 13.7 0.4 0.041 13.3 0.4 1.2 1 0 0 1 1 1 0 IRSp53/MIM homology domain Ribonuc_red_sm PF00268.21 KFX88460.1 - 2.3e-114 381.6 2.4 2.8e-114 381.3 2.4 1.1 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain SRP9-21 PF05486.12 KFX88461.1 - 1.4e-30 105.5 0.8 1.9e-30 105.1 0.8 1.2 1 0 0 1 1 1 1 Signal recognition particle 9 kDa protein (SRP9) DUF1308 PF07000.11 KFX88462.1 - 9e-10 38.7 0.0 1.3e-08 34.9 0.0 2.6 2 1 0 2 2 2 1 Protein of unknown function (DUF1308) DUF5614 PF18474.1 KFX88462.1 - 2.6e-06 26.9 0.0 0.035 13.4 0.0 2.8 2 1 0 2 2 2 2 Family of unknown function (DUF5614) Sigma70_r1_1 PF03979.14 KFX88462.1 - 0.049 13.7 0.0 0.15 12.1 0.0 1.8 1 0 0 1 1 1 0 Sigma-70 factor, region 1.1 Aminotran_1_2 PF00155.21 KFX88469.1 - 2.2e-16 60.0 0.0 3e-16 59.6 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.7 KFX88469.1 - 0.0023 16.8 0.0 0.009 14.8 0.0 1.8 2 1 0 2 2 2 1 Alanine-glyoxylate amino-transferase UCR_14kD PF02271.16 KFX88472.1 - 1.6e-44 149.9 0.0 1.9e-44 149.7 0.0 1.0 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase complex 14kD subunit G-alpha PF00503.20 KFX88490.1 - 9.1e-86 288.2 6.0 1e-85 288.0 6.0 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 KFX88490.1 - 1.7e-11 43.9 0.3 3.8e-11 42.7 0.3 1.6 1 1 0 1 1 1 1 ADP-ribosylation factor family zf-CHC2 PF01807.20 KFX88490.1 - 1.4e-05 24.8 0.1 7.5e-05 22.5 0.0 2.0 2 0 0 2 2 2 1 CHC2 zinc finger adh_short_C2 PF13561.6 KFX88502.1 - 2.3e-52 177.9 0.8 2.7e-52 177.7 0.8 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KFX88502.1 - 8.4e-44 149.4 0.6 9.9e-44 149.1 0.6 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KFX88502.1 - 7.7e-12 45.5 0.7 1e-11 45.1 0.7 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KFX88502.1 - 0.0039 16.7 0.0 0.0063 16.0 0.0 1.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_2 PF03446.15 KFX88502.1 - 0.0052 17.0 0.4 0.11 12.7 0.2 2.1 1 1 1 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase HATPase_c PF02518.26 KFX88502.1 - 0.021 15.3 0.0 0.041 14.4 0.0 1.5 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 3Beta_HSD PF01073.19 KFX88502.1 - 0.07 12.1 0.0 0.11 11.5 0.0 1.3 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family PhoD PF09423.10 KFX88504.1 - 5.3e-05 22.4 0.0 0.00015 20.9 0.0 1.7 1 1 0 1 1 1 1 PhoD-like phosphatase SMC_N PF02463.19 KFX88506.1 - 1e-31 110.1 22.7 2.5e-31 108.9 21.5 2.0 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 KFX88506.1 - 1.3e-26 93.2 0.0 3e-26 92.0 0.0 1.7 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain AAA_23 PF13476.6 KFX88506.1 - 3.4e-13 50.6 24.3 3.4e-13 50.6 24.3 5.0 2 2 1 3 3 3 1 AAA domain AAA_15 PF13175.6 KFX88506.1 - 7.7e-09 35.7 28.6 1.4e-08 34.9 19.2 3.5 2 1 0 2 2 2 1 AAA ATPase domain AAA_21 PF13304.6 KFX88506.1 - 3.1e-06 27.2 0.2 3.1e-06 27.2 0.2 2.6 2 1 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 KFX88506.1 - 0.0075 16.0 0.0 0.017 14.8 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain ABC_tran PF00005.27 KFX88506.1 - 0.42 11.1 0.0 0.42 11.1 0.0 4.3 3 3 1 4 4 4 0 ABC transporter DASH_Dam1 PF08653.10 KFX88506.1 - 0.87 9.4 8.8 8.1 6.3 0.2 4.8 4 0 0 4 4 4 0 DASH complex subunit Dam1 Spc7 PF08317.11 KFX88506.1 - 3.5 6.4 78.0 0.34 9.7 3.8 5.7 2 2 1 5 5 5 0 Spc7 kinetochore protein APG6_N PF17675.1 KFX88506.1 - 7.9 7.0 92.7 0.17 12.4 8.7 7.1 3 2 3 6 6 6 0 Apg6 coiled-coil region RIO1 PF01163.22 KFX88507.1 - 6.4e-67 224.8 0.0 6.4e-67 224.8 0.0 1.7 2 0 0 2 2 2 1 RIO1 family Kdo PF06293.14 KFX88507.1 - 0.0037 16.6 0.3 0.032 13.6 0.3 2.2 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KFX88507.1 - 0.013 15.4 1.2 1.2 9.0 0.1 2.7 2 1 0 3 3 3 0 Phosphotransferase enzyme family Prismane PF03063.20 KFX88507.1 - 0.053 12.2 0.0 0.088 11.5 0.0 1.2 1 0 0 1 1 1 0 Prismane/CO dehydrogenase family PGA2 PF07543.12 KFX88507.1 - 7 6.6 15.1 5.9 6.9 9.6 2.7 2 0 0 2 2 2 0 Protein trafficking PGA2 SNARE PF05739.19 KFX88508.1 - 1.3e-14 53.9 1.0 2.4e-14 53.0 1.0 1.5 1 0 0 1 1 1 1 SNARE domain Syntaxin PF00804.25 KFX88508.1 - 4.2e-05 23.3 7.0 0.0009 19.0 7.0 2.2 1 1 0 1 1 1 1 Syntaxin MCPsignal PF00015.21 KFX88508.1 - 0.003 17.4 4.1 0.011 15.6 0.3 2.5 3 0 0 3 3 3 1 Methyl-accepting chemotaxis protein (MCP) signalling domain Syntaxin_2 PF14523.6 KFX88508.1 - 0.033 14.5 1.5 0.033 14.5 1.5 2.3 2 0 0 2 2 2 0 Syntaxin-like protein DNA_repr_REX1B PF14966.6 KFX88508.1 - 0.25 12.0 0.1 0.25 12.0 0.1 2.5 3 1 0 3 3 3 0 DNA repair REX1-B EF-hand_1 PF00036.32 KFX88509.1 - 4.7e-41 135.3 12.9 1.1e-09 37.1 0.9 4.2 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 KFX88509.1 - 1.5e-35 121.5 5.7 1.1e-18 67.4 2.2 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 KFX88509.1 - 3.2e-34 116.6 11.6 2.4e-15 56.1 0.5 4.1 1 1 3 4 4 4 4 EF-hand domain pair EF-hand_6 PF13405.6 KFX88509.1 - 5.4e-30 100.7 8.8 2.8e-09 36.2 0.2 4.4 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 KFX88509.1 - 2.6e-25 86.7 10.6 3.7e-06 26.2 0.3 4.3 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.6 KFX88509.1 - 2.3e-16 59.9 0.3 3.9e-09 36.7 0.0 2.2 2 0 0 2 2 2 2 EF-hand domain SPARC_Ca_bdg PF10591.9 KFX88509.1 - 2.4e-09 37.5 0.6 0.002 18.4 0.1 2.1 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 KFX88509.1 - 3.4e-08 33.4 2.9 0.0034 17.3 0.2 2.7 1 1 2 3 3 3 2 Cytoskeletal-regulatory complex EF hand UPF0154 PF03672.13 KFX88509.1 - 2e-06 27.7 0.1 0.012 15.6 0.0 2.9 2 1 1 3 3 3 2 Uncharacterised protein family (UPF0154) EFhand_Ca_insen PF08726.10 KFX88509.1 - 4.1e-05 23.6 1.5 0.00015 21.8 0.2 2.4 2 1 0 2 2 2 1 Ca2+ insensitive EF hand EF-hand_11 PF08976.11 KFX88509.1 - 5.4e-05 24.0 0.2 0.0012 19.7 0.1 2.2 1 1 1 2 2 2 1 EF-hand domain TerB PF05099.13 KFX88509.1 - 0.00017 21.5 0.4 0.5 10.3 0.0 2.4 1 1 1 2 2 2 2 Tellurite resistance protein TerB RNA_pol_Rpb4 PF03874.16 KFX88509.1 - 0.0011 19.3 0.8 1 9.7 0.1 2.8 2 1 0 2 2 2 2 RNA polymerase Rpb4 Caleosin PF05042.13 KFX88509.1 - 0.0022 17.9 3.3 0.7 9.8 0.0 3.5 1 1 3 4 4 4 1 Caleosin related protein Dockerin_1 PF00404.18 KFX88509.1 - 0.0082 16.3 6.3 0.48 10.7 0.4 3.0 1 1 2 3 3 3 2 Dockerin type I domain DUF5580 PF17743.1 KFX88509.1 - 0.014 13.9 0.0 0.016 13.8 0.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5580) EF-hand_14 PF17959.1 KFX88509.1 - 0.018 15.4 0.3 8.5 6.8 0.1 2.6 1 1 1 2 2 2 0 EF-hand domain SurA_N_2 PF13623.6 KFX88509.1 - 0.028 14.3 2.1 0.6 10.0 0.1 2.4 1 1 1 2 2 2 0 SurA N-terminal domain DUF4497 PF14924.6 KFX88509.1 - 0.031 14.8 0.0 7.8 7.0 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4497) Poly_export PF02563.16 KFX88509.1 - 0.036 14.3 0.0 0.28 11.4 0.0 2.5 2 1 0 2 2 2 0 Polysaccharide biosynthesis/export protein RloB PF13707.6 KFX88509.1 - 0.047 13.9 2.6 1.3 9.2 2.6 2.1 1 1 0 1 1 1 0 RloB-like protein MotA_activ PF09114.10 KFX88509.1 - 0.1 12.7 0.2 2 8.6 0.0 2.3 1 1 0 2 2 2 0 Transcription factor MotA, activation domain RuvA_C PF07499.13 KFX88509.1 - 0.2 12.2 0.1 14 6.2 0.1 3.0 3 0 0 3 3 3 0 RuvA, C-terminal domain Glyco_hydro_47 PF01532.20 KFX88510.1 - 7e-177 588.9 0.0 8.2e-177 588.7 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Glyco_hydro_88 PF07470.13 KFX88510.1 - 0.073 12.1 0.0 0.86 8.6 0.0 2.1 2 0 0 2 2 2 0 Glycosyl Hydrolase Family 88 DUF1679 PF07914.11 KFX88513.1 - 0.25 10.2 0.0 0.38 9.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) APH PF01636.23 KFX88514.1 - 0.0031 17.5 0.0 0.0039 17.1 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family CIAPIN1 PF05093.13 KFX88515.1 - 3.3e-41 139.9 2.4 5.4e-41 139.2 2.4 1.3 1 0 0 1 1 1 1 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis DRE2_N PF16803.5 KFX88515.1 - 2.8e-38 131.1 0.0 4e-38 130.6 0.0 1.2 1 0 0 1 1 1 1 Fe-S cluster assembly protein DRE2 N-terminus Ferric_reduct PF01794.19 KFX88518.1 - 1.8e-24 86.2 9.0 1.8e-24 86.2 9.0 3.0 4 0 0 4 4 4 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 KFX88518.1 - 2.2e-21 76.6 0.1 2e-19 70.3 0.1 2.2 1 1 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 KFX88518.1 - 2.4e-09 37.3 0.0 3e-07 30.5 0.0 2.6 2 1 0 2 2 2 1 FAD-binding domain 8TM_micro PF17028.5 KFX88520.1 - 0.046 13.4 0.6 0.073 12.8 0.6 1.2 1 0 0 1 1 1 0 8TM Microsporidial transmembrane domain Tsc35 PF15079.6 KFX88520.1 - 0.17 11.5 0.1 0.27 10.8 0.1 1.3 1 0 0 1 1 1 0 Testis-specific protein 35 DAO PF01266.24 KFX88531.1 - 1.8e-41 142.9 0.0 2.1e-41 142.7 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 KFX88531.1 - 0.0084 16.1 0.1 0.78 9.7 0.0 2.4 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_3 PF13738.6 KFX88531.1 - 0.012 14.9 0.0 0.023 14.0 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KFX88531.1 - 0.05 13.8 0.0 0.11 12.7 0.0 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Prefoldin PF02996.17 KFX88532.1 - 0.56 10.1 5.7 2.9 7.8 0.1 2.8 2 1 0 2 2 2 0 Prefoldin subunit DUF92 PF01940.16 KFX88533.1 - 3.9e-87 291.6 2.4 5.1e-87 291.2 2.4 1.1 1 0 0 1 1 1 1 Integral membrane protein DUF92 FAD_binding_3 PF01494.19 KFX88533.1 - 9.1e-37 127.1 0.8 1.3e-36 126.6 0.8 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 KFX88533.1 - 1e-05 24.9 0.3 0.069 12.4 0.0 2.4 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KFX88533.1 - 6.8e-05 22.3 0.0 0.0019 17.5 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KFX88533.1 - 0.0011 18.7 0.1 0.1 12.2 0.0 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.17 KFX88533.1 - 0.0015 17.8 0.0 0.0028 16.9 0.0 1.4 1 0 0 1 1 1 1 Thi4 family Pyr_redox PF00070.27 KFX88533.1 - 0.04 14.5 0.4 28 5.4 0.0 3.2 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KFX88533.1 - 0.055 12.5 0.3 0.65 9.0 0.0 2.1 2 0 0 2 2 2 0 Lycopene cyclase protein DUF3522 PF12036.8 KFX88533.1 - 0.095 13.0 0.5 0.21 11.9 0.4 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3522) FAA_hydrolase PF01557.18 KFX88534.1 - 1.3e-49 168.8 0.0 2.4e-49 168.0 0.0 1.4 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family Fungal_trans PF04082.18 KFX88534.1 - 3.6e-14 52.4 0.4 2e-13 50.0 0.5 2.2 4 0 0 4 4 4 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KFX88534.1 - 0.0018 18.4 18.1 0.002 18.2 15.4 2.4 2 1 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain UPF0565 PF10561.9 KFX88534.1 - 0.075 12.2 0.0 0.25 10.5 0.0 1.8 2 0 0 2 2 2 0 Uncharacterised protein family UPF0565 Glyoxalase PF00903.25 KFX88535.1 - 1.8e-10 41.1 3.2 3.3e-09 37.0 1.4 2.3 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily FAD_binding_3 PF01494.19 KFX88536.1 - 1.7e-33 116.3 0.0 3.7e-18 65.9 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 KFX88536.1 - 0.00031 20.9 0.1 0.00067 19.8 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 KFX88536.1 - 0.00059 19.2 0.6 0.00097 18.5 0.6 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KFX88536.1 - 0.00089 18.6 0.1 0.0015 17.9 0.1 1.3 1 0 0 1 1 1 1 Thi4 family Lycopene_cycl PF05834.12 KFX88536.1 - 0.16 11.0 1.3 1.6 7.7 0.3 2.1 2 0 0 2 2 2 0 Lycopene cyclase protein Pyr_redox_2 PF07992.14 KFX88536.1 - 0.24 10.6 0.3 0.87 8.8 0.1 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 KFX88537.1 - 3.7e-48 164.6 0.1 4.7e-48 164.2 0.1 1.1 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 KFX88537.1 - 1.9e-07 31.0 0.8 0.00033 20.4 0.1 2.2 1 1 1 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KFX88537.1 - 3.1e-06 26.7 0.1 0.0034 16.6 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KFX88537.1 - 1.3e-05 25.6 0.0 0.0035 17.9 0.0 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KFX88537.1 - 1.8e-05 24.9 0.2 4.8e-05 23.5 0.0 1.8 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 KFX88537.1 - 2.4e-05 23.3 0.1 0.003 16.3 0.0 2.1 2 0 0 2 2 2 1 HI0933-like protein Thi4 PF01946.17 KFX88537.1 - 0.00024 20.5 0.0 0.00049 19.4 0.0 1.4 1 0 0 1 1 1 1 Thi4 family FAD_binding_2 PF00890.24 KFX88537.1 - 0.0011 18.1 0.5 0.0047 16.1 0.1 2.0 1 1 1 2 2 2 1 FAD binding domain Pyr_redox_3 PF13738.6 KFX88537.1 - 0.0012 18.2 0.0 0.0062 15.8 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 KFX88537.1 - 0.0018 17.2 0.4 0.24 10.2 0.1 2.3 1 1 1 2 2 2 1 Tryptophan halogenase FAD_oxidored PF12831.7 KFX88537.1 - 0.0074 15.7 1.1 0.032 13.6 1.1 1.9 1 1 0 1 1 1 1 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.21 KFX88537.1 - 0.01 15.2 0.1 0.017 14.4 0.1 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain GIDA PF01134.22 KFX88537.1 - 0.016 14.3 0.0 0.021 13.9 0.0 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A 3HCDH_N PF02737.18 KFX88537.1 - 0.029 14.3 0.1 0.048 13.5 0.1 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_7 PF13241.6 KFX88537.1 - 0.033 14.6 0.0 0.089 13.2 0.0 1.7 1 1 0 1 1 1 0 Putative NAD(P)-binding 2-Hacid_dh_C PF02826.19 KFX88537.1 - 0.042 13.2 0.0 0.073 12.4 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.14 KFX88537.1 - 0.063 12.8 0.1 0.96 9.0 0.0 2.4 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain ApbA PF02558.16 KFX88537.1 - 0.074 12.7 0.1 0.13 11.9 0.1 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA XdhC_C PF13478.6 KFX88537.1 - 0.096 13.2 0.1 0.21 12.1 0.1 1.6 1 0 0 1 1 1 0 XdhC Rossmann domain Amino_oxidase PF01593.24 KFX88537.1 - 0.15 11.4 0.5 14 4.8 0.0 2.8 3 0 0 3 3 3 0 Flavin containing amine oxidoreductase Cellulase PF00150.18 KFX88558.1 - 3.8e-11 43.0 0.6 1.1e-10 41.4 0.0 1.9 2 0 0 2 2 2 1 Cellulase (glycosyl hydrolase family 5) DUF4246 PF14033.6 KFX88559.1 - 2.7e-141 471.8 0.0 3.2e-141 471.5 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4246) COesterase PF00135.28 KFX88560.1 - 2.1e-83 281.0 0.1 2.4e-83 280.8 0.1 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KFX88560.1 - 0.015 15.1 0.3 0.061 13.2 0.3 1.9 1 1 0 1 1 1 0 alpha/beta hydrolase fold Zn_clus PF00172.18 KFX88561.1 - 1.3e-07 31.6 12.2 2.5e-07 30.7 12.2 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KFX88562.1 - 3.7e-24 85.2 0.3 7.6e-24 84.2 0.3 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain MFS_1 PF07690.16 KFX88563.1 - 3e-31 108.6 22.2 4.1e-31 108.2 22.2 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily DHDPS PF00701.22 KFX88564.1 - 7.2e-33 113.5 0.0 8.6e-33 113.3 0.0 1.1 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family PA PF02225.22 KFX88564.1 - 0.056 13.5 0.1 0.11 12.6 0.1 1.5 1 0 0 1 1 1 0 PA domain Mito_carr PF00153.27 KFX88565.1 - 4.5e-43 145.1 6.8 4.4e-17 61.8 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein HA2 PF04408.23 KFX88567.1 - 1.7e-19 70.1 0.0 3e-19 69.3 0.0 1.4 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.31 KFX88567.1 - 2.6e-12 47.1 0.0 8.6e-12 45.4 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain OB_NTP_bind PF07717.16 KFX88567.1 - 5.1e-09 36.4 0.0 1.6e-08 34.8 0.0 1.8 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold zf-C2H2 PF00096.26 KFX88574.1 - 3.7e-05 23.9 7.2 0.0052 17.2 0.3 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFX88574.1 - 0.029 15.2 6.4 0.79 10.7 0.3 2.9 2 0 0 2 2 2 0 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KFX88574.1 - 1 9.9 7.2 1.4 9.5 2.4 3.0 2 0 0 2 2 2 0 Zinc-finger double domain Atx10homo_assoc PF09759.9 KFX88576.1 - 1.8e-14 53.5 0.0 5.9e-14 51.9 0.0 1.9 1 0 0 1 1 1 1 Spinocerebellar ataxia type 10 protein domain KH_1 PF00013.29 KFX88576.1 - 3.1e-14 52.5 0.9 5.9e-13 48.4 0.2 2.6 2 0 0 2 2 2 1 KH domain Glyoxalase PF00903.25 KFX88577.1 - 6e-35 120.2 0.0 2.5e-16 60.0 0.1 2.2 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 KFX88577.1 - 5.8e-13 49.1 0.0 8.1e-05 22.9 0.0 3.6 2 2 1 3 3 3 3 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_6 PF18029.1 KFX88577.1 - 8.1e-10 39.5 0.0 0.00077 20.2 0.0 2.9 3 1 0 3 3 3 2 Glyoxalase-like domain Glyoxalase_3 PF13468.6 KFX88577.1 - 9.6e-06 25.8 0.0 0.069 13.3 0.0 2.4 2 0 0 2 2 2 2 Glyoxalase-like domain Glyoxalase_2 PF12681.7 KFX88577.1 - 0.0041 17.0 0.4 54 3.7 0.0 4.2 4 0 0 4 4 4 0 Glyoxalase-like domain MoaF PF10703.9 KFX88577.1 - 0.046 13.7 0.0 0.95 9.4 0.0 2.3 2 0 0 2 2 2 0 MoaF N-terminal domain DUF1338 PF07063.13 KFX88577.1 - 0.049 12.8 0.0 10 5.2 0.0 3.4 4 0 0 4 4 4 0 Domain of unknown function (DUF1338) GFA PF04828.14 KFX88579.1 - 5.5e-26 90.8 0.1 7.9e-26 90.2 0.1 1.2 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme Acetyltransf_2 PF00797.17 KFX88580.1 - 4.7e-42 144.4 0.0 6.9e-42 143.9 0.0 1.2 1 0 0 1 1 1 1 N-acetyltransferase NACHT_N PF17100.5 KFX88583.1 - 6e-27 94.9 0.2 1.1e-26 94.1 0.2 1.4 1 0 0 1 1 1 1 N-terminal domain of NWD NACHT-NTPase NACHT PF05729.12 KFX88583.1 - 1.2e-10 41.6 0.0 3e-10 40.3 0.0 1.7 1 0 0 1 1 1 1 NACHT domain AAA_25 PF13481.6 KFX88583.1 - 0.00011 21.8 0.0 0.00027 20.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KFX88583.1 - 0.00061 20.2 0.0 0.0032 17.9 0.0 2.2 3 0 0 3 3 3 1 AAA ATPase domain AAA_22 PF13401.6 KFX88583.1 - 0.002 18.4 0.0 0.026 14.8 0.0 2.4 2 0 0 2 2 2 1 AAA domain KAP_NTPase PF07693.14 KFX88583.1 - 0.013 14.8 0.1 0.18 11.0 0.0 2.2 1 1 0 2 2 2 0 KAP family P-loop domain RNA_helicase PF00910.22 KFX88583.1 - 0.036 14.5 0.0 1.7 9.1 0.0 3.0 3 0 0 3 3 3 0 RNA helicase NB-ARC PF00931.22 KFX88583.1 - 0.046 12.9 0.0 0.18 10.9 0.0 2.0 1 1 0 1 1 1 0 NB-ARC domain AAA_33 PF13671.6 KFX88583.1 - 0.13 12.4 0.2 12 6.0 0.0 2.8 3 0 0 3 3 3 0 AAA domain CorA PF01544.18 KFX88584.1 - 6.7e-05 22.3 0.0 0.00012 21.5 0.0 1.3 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein VKOR PF07884.14 KFX88584.1 - 0.048 13.9 1.3 0.14 12.4 1.3 1.8 1 1 0 1 1 1 0 Vitamin K epoxide reductase family CTP_transf_like PF01467.26 KFX88590.1 - 1.3e-17 64.3 0.0 2.9e-17 63.2 0.0 1.5 1 0 0 1 1 1 1 Cytidylyltransferase-like Cutinase PF01083.22 KFX88590.1 - 3.2e-05 24.0 0.0 0.00021 21.3 0.0 2.3 2 0 0 2 2 2 1 Cutinase PGAP1 PF07819.13 KFX88590.1 - 0.11 12.2 0.0 0.22 11.2 0.0 1.4 1 0 0 1 1 1 0 PGAP1-like protein Palm_thioest PF02089.15 KFX88590.1 - 0.17 11.7 0.0 0.28 11.0 0.0 1.3 1 0 0 1 1 1 0 Palmitoyl protein thioesterase TPR_12 PF13424.6 KFX88591.1 - 1.6e-53 178.9 24.5 1.2e-13 51.1 1.3 6.0 3 2 2 5 5 5 5 Tetratricopeptide repeat TPR_10 PF13374.6 KFX88591.1 - 7e-53 175.2 25.3 7.3e-08 32.0 0.5 8.7 8 0 0 8 8 8 8 Tetratricopeptide repeat TPR_7 PF13176.6 KFX88591.1 - 2.9e-19 67.6 21.9 0.024 14.7 0.0 8.5 8 0 0 8 8 8 5 Tetratricopeptide repeat TPR_1 PF00515.28 KFX88591.1 - 4.2e-18 64.3 37.4 0.0016 18.2 1.5 9.4 10 0 0 10 10 9 7 Tetratricopeptide repeat TPR_2 PF07719.17 KFX88591.1 - 3.8e-15 54.7 31.4 0.0012 18.8 2.2 8.9 9 0 0 9 9 8 5 Tetratricopeptide repeat TPR_19 PF14559.6 KFX88591.1 - 4.7e-12 46.2 17.9 0.0081 16.7 0.0 6.6 2 2 4 6 6 6 5 Tetratricopeptide repeat TPR_MalT PF17874.1 KFX88591.1 - 7.8e-12 45.2 15.9 3.5e-07 29.9 4.7 3.1 1 1 1 2 2 2 2 MalT-like TPR region TPR_16 PF13432.6 KFX88591.1 - 1.2e-10 41.8 27.8 0.0012 19.5 0.1 7.9 7 2 0 7 7 7 4 Tetratricopeptide repeat TPR_8 PF13181.6 KFX88591.1 - 1.2e-09 37.6 21.3 0.11 12.8 0.0 8.2 9 0 0 9 9 7 3 Tetratricopeptide repeat NB-ARC PF00931.22 KFX88591.1 - 1.8e-09 37.1 0.0 9.4e-09 34.8 0.0 2.0 2 0 0 2 2 2 1 NB-ARC domain ANAPC3 PF12895.7 KFX88591.1 - 2.8e-09 37.0 19.0 0.044 14.0 2.2 6.5 3 2 4 7 7 6 4 Anaphase-promoting complex, cyclosome, subunit 3 PNP_UDP_1 PF01048.20 KFX88591.1 - 1.1e-08 34.6 0.0 1.8e-08 33.9 0.0 1.3 1 0 0 1 1 1 1 Phosphorylase superfamily TPR_4 PF07721.14 KFX88591.1 - 1.6e-08 34.4 6.1 3.9 8.4 0.2 7.2 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_14 PF13428.6 KFX88591.1 - 5.4e-08 33.0 20.0 0.94 10.5 0.2 9.0 6 2 3 9 9 8 2 Tetratricopeptide repeat TPR_17 PF13431.6 KFX88591.1 - 8.5e-08 32.1 19.9 0.075 13.5 0.1 8.4 8 0 0 8 8 8 2 Tetratricopeptide repeat AAA_16 PF13191.6 KFX88591.1 - 0.00018 22.0 0.0 0.0011 19.4 0.0 2.3 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 KFX88591.1 - 0.00038 20.7 0.0 0.0012 19.1 0.0 1.8 1 0 0 1 1 1 1 AAA domain TPR_11 PF13414.6 KFX88591.1 - 0.00081 19.0 29.6 0.0059 16.3 0.3 6.4 6 1 0 6 6 5 2 TPR repeat ATPase_2 PF01637.18 KFX88591.1 - 0.0017 18.3 0.0 0.0031 17.4 0.0 1.4 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea TniB PF05621.11 KFX88591.1 - 0.0038 16.6 0.0 0.0089 15.5 0.0 1.5 1 0 0 1 1 1 1 Bacterial TniB protein TPR_3 PF07720.12 KFX88591.1 - 0.011 15.8 21.9 3.2 7.9 0.5 6.5 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_6 PF13174.6 KFX88591.1 - 0.012 16.1 21.4 0.3 11.8 0.0 7.6 9 0 0 9 9 8 0 Tetratricopeptide repeat SRP54 PF00448.22 KFX88591.1 - 0.027 14.1 0.0 0.081 12.5 0.0 1.8 2 0 0 2 2 1 0 SRP54-type protein, GTPase domain IstB_IS21 PF01695.17 KFX88591.1 - 0.037 13.7 0.0 0.12 12.1 0.0 1.8 1 0 0 1 1 1 0 IstB-like ATP binding protein DUF4404 PF14357.6 KFX88591.1 - 0.039 14.6 0.8 1.5 9.5 0.0 3.1 2 1 0 2 2 2 0 Domain of unknown function (DUF4404) BTAD PF03704.17 KFX88591.1 - 0.13 12.7 15.0 8.3 6.8 0.8 4.8 2 2 2 4 4 4 0 Bacterial transcriptional activator domain TPR_20 PF14561.6 KFX88591.1 - 0.23 11.8 6.0 5.9 7.3 0.1 4.6 2 2 3 5 5 5 0 Tetratricopeptide repeat SHNi-TPR PF10516.9 KFX88591.1 - 0.25 10.8 6.8 18 4.9 0.1 4.1 4 0 0 4 4 4 0 SHNi-TPR DUF1925 PF09094.11 KFX88591.1 - 0.27 11.6 2.0 6.2 7.2 0.0 3.9 3 2 2 5 5 4 0 Domain of unknown function (DUF1925) MIT PF04212.18 KFX88591.1 - 3.9 7.6 12.6 2.2 8.4 0.1 4.9 5 1 1 6 6 6 0 MIT (microtubule interacting and transport) domain Pyrophosphatase PF00719.19 KFX88594.1 - 4e-58 195.7 0.1 5.1e-58 195.4 0.1 1.1 1 0 0 1 1 1 1 Inorganic pyrophosphatase SUI1 PF01253.22 KFX88600.1 - 8.8e-28 96.7 3.9 1.5e-27 95.9 3.9 1.4 1 0 0 1 1 1 1 Translation initiation factor SUI1 UPF0139 PF03669.13 KFX88601.1 - 7.6e-05 22.5 0.0 0.0001 22.1 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0139) PUF PF00806.19 KFX88624.1 - 5.7e-57 186.3 11.7 8e-08 31.6 0.1 8.6 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat Zn_clus PF00172.18 KFX88626.1 - 3.7e-10 39.8 8.5 8.3e-10 38.6 8.5 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ADH_zinc_N_2 PF13602.6 KFX88627.1 - 1e-21 78.4 0.0 1.8e-21 77.6 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 KFX88627.1 - 5.4e-13 49.1 0.0 9.6e-13 48.2 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KFX88627.1 - 8.9e-07 28.8 0.0 1.7e-06 27.8 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Semialdhyde_dh PF01118.24 KFX88627.1 - 2.4e-05 24.8 0.1 4.2e-05 24.0 0.1 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain DapB_N PF01113.20 KFX88627.1 - 0.00011 22.3 1.1 0.0002 21.5 0.3 1.9 2 0 0 2 2 2 1 Dihydrodipicolinate reductase, N-terminus DUF2855 PF11017.8 KFX88627.1 - 0.002 18.0 0.0 0.0026 17.6 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2855) RmlD_sub_bind PF04321.17 KFX88627.1 - 0.011 14.9 0.6 0.021 13.9 0.0 1.7 2 0 0 2 2 2 0 RmlD substrate binding domain THF_DHG_CYH_C PF02882.19 KFX88627.1 - 0.059 12.7 0.4 0.26 10.6 0.4 1.9 1 1 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Pyr_redox_2 PF07992.14 KFX88628.1 - 2.7e-43 148.3 0.3 3.2e-43 148.1 0.3 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KFX88628.1 - 1.1e-11 45.1 4.4 1.2e-09 38.6 0.3 2.5 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KFX88628.1 - 3.1e-07 30.3 6.8 0.19 11.3 0.1 4.1 4 0 0 4 4 4 3 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KFX88628.1 - 0.0068 16.6 0.6 4.9 7.4 0.2 2.7 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 KFX88628.1 - 0.027 14.5 4.8 4.3 7.3 0.1 3.4 4 0 0 4 4 4 0 FAD-NAD(P)-binding FAD_binding_2 PF00890.24 KFX88628.1 - 0.075 12.1 2.4 0.23 10.5 0.3 2.3 2 0 0 2 2 2 0 FAD binding domain Pyr_redox_3 PF13738.6 KFX88628.1 - 0.23 10.7 0.1 11 5.1 0.0 2.7 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KFX88628.1 - 0.26 10.4 0.3 0.5 9.5 0.0 1.5 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) Abhydrolase_6 PF12697.7 KFX88628.1 - 0.44 11.1 3.7 1.5 9.3 0.3 2.2 1 1 0 2 2 2 0 Alpha/beta hydrolase family GIDA PF01134.22 KFX88628.1 - 0.45 9.6 4.4 4.7 6.2 0.2 3.5 4 0 0 4 4 4 0 Glucose inhibited division protein A Trp_halogenase PF04820.14 KFX88628.1 - 7.8 5.2 5.9 7.6 5.3 0.6 2.7 3 0 0 3 3 3 0 Tryptophan halogenase CaM-KIIN PF15170.6 KFX88633.1 - 0.13 12.5 0.1 0.24 11.6 0.1 1.4 1 0 0 1 1 1 0 Calcium/calmodulin-dependent protein kinase II inhibitor fn3_3 PF14686.6 KFX88658.1 - 1.6e-27 95.1 0.4 3.7e-27 93.9 0.4 1.7 1 0 0 1 1 1 1 Polysaccharide lyase family 4, domain II CBM-like PF14683.6 KFX88658.1 - 1.6e-26 93.2 0.1 2.6e-26 92.5 0.1 1.4 1 0 0 1 1 1 1 Polysaccharide lyase family 4, domain III Choline_kinase PF01633.20 KFX88660.1 - 6.2e-61 205.7 0.0 1.8e-60 204.2 0.0 1.7 2 0 0 2 2 2 1 Choline/ethanolamine kinase Choline_kin_N PF04428.14 KFX88660.1 - 5e-22 77.3 0.1 1.2e-21 76.1 0.0 1.7 2 0 0 2 2 2 1 Choline kinase N terminus APH PF01636.23 KFX88660.1 - 2.9e-06 27.4 0.1 7.1e-06 26.1 0.1 1.7 1 0 0 1 1 1 1 Phosphotransferase enzyme family Aldo_ket_red PF00248.21 KFX88662.1 - 3.5e-15 56.0 0.0 4.1e-15 55.7 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family HLH PF00010.26 KFX88664.1 - 1.1e-11 44.5 1.8 3.2e-11 43.0 1.8 1.8 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain DUF4776 PF16003.5 KFX88664.1 - 0.046 12.7 2.3 0.07 12.1 2.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4776) Ly49 PF08391.10 KFX88664.1 - 0.071 13.5 0.9 0.14 12.5 0.9 1.5 1 0 0 1 1 1 0 Ly49-like protein, N-terminal region CBP4 PF07960.11 KFX88664.1 - 0.84 9.5 11.0 1.2 8.9 9.4 2.0 2 0 0 2 2 2 0 CBP4 Mod_r PF07200.13 KFX88664.1 - 1 9.5 8.9 0.25 11.5 4.8 2.1 2 1 1 3 3 3 0 Modifier of rudimentary (Mod(r)) protein DUF4239 PF14023.6 KFX88664.1 - 1.3 8.7 2.5 2.2 7.9 2.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4239) APG6_N PF17675.1 KFX88664.1 - 2 9.0 11.0 4.5 7.8 11.0 1.6 1 1 0 1 1 1 0 Apg6 coiled-coil region DivIC PF04977.15 KFX88664.1 - 8.4 6.2 6.6 1 9.2 2.0 1.9 2 0 0 2 2 2 0 Septum formation initiator Tcp11 PF05794.13 KFX88667.1 - 9.1e-109 364.5 0.6 9.1e-109 364.5 0.6 2.3 2 0 0 2 2 2 1 T-complex protein 11 UPF0242 PF06785.11 KFX88667.1 - 4 7.5 5.2 10 6.2 5.2 1.6 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Mito_carr PF00153.27 KFX88669.1 - 2.7e-66 219.5 4.9 4.4e-24 84.2 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF4748 PF15932.5 KFX88669.1 - 0.08 12.7 0.6 0.27 11.0 0.6 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4748) DUF21 PF01595.20 KFX88670.1 - 3.7e-25 88.6 1.5 6e-25 88.0 1.5 1.2 1 0 0 1 1 1 1 Cyclin M transmembrane N-terminal domain RRM_1 PF00076.22 KFX88670.1 - 0.0014 18.4 0.0 0.003 17.4 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PTPRCAP PF15713.5 KFX88670.1 - 0.2 12.0 3.1 0.48 10.7 3.1 1.6 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated DUF2304 PF10066.9 KFX88670.1 - 0.23 11.7 1.9 0.28 11.4 0.3 1.9 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2304) SET PF00856.28 KFX88671.1 - 4.2e-13 50.0 0.0 5.8e-13 49.6 0.0 1.2 1 0 0 1 1 1 1 SET domain Coq4 PF05019.13 KFX88672.1 - 5.2e-98 326.8 0.0 6.2e-98 326.5 0.0 1.1 1 0 0 1 1 1 1 Coenzyme Q (ubiquinone) biosynthesis protein Coq4 dsDNA_bind PF01984.20 KFX88673.1 - 3.8e-41 139.8 7.6 4.4e-41 139.6 7.6 1.0 1 0 0 1 1 1 1 Double-stranded DNA-binding domain cwf18 PF08315.12 KFX88673.1 - 0.0034 18.1 0.8 0.0046 17.6 0.8 1.2 1 0 0 1 1 1 1 cwf18 pre-mRNA splicing factor LigT_PEase PF02834.16 KFX88673.1 - 0.16 12.2 0.2 0.43 10.8 0.2 1.8 1 1 0 1 1 1 0 LigT like Phosphoesterase ApbA_C PF08546.11 KFX88674.1 - 8.9e-22 77.6 0.1 1.7e-21 76.7 0.1 1.5 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.16 KFX88674.1 - 5.3e-17 61.9 0.0 1.3e-16 60.6 0.0 1.7 1 1 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Sas10_Utp3 PF04000.15 KFX88675.1 - 2.1e-16 60.3 0.1 2.1e-16 60.3 0.1 2.6 2 1 0 2 2 2 1 Sas10/Utp3/C1D family SRP-alpha_N PF04086.13 KFX88675.1 - 0.35 10.7 23.2 0.43 10.5 23.2 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal DUF2868 PF11067.8 KFX88675.1 - 2 7.9 3.7 3.6 7.0 3.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2868) DUF2076 PF09849.9 KFX88676.1 - 2.2e-07 31.2 10.7 2.5e-07 31.0 10.7 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2076) CHCH PF06747.13 KFX88676.1 - 0.00011 22.2 6.5 0.00015 21.8 6.5 1.2 1 0 0 1 1 1 1 CHCH domain CX9C PF16860.5 KFX88676.1 - 0.019 15.0 3.6 0.029 14.4 3.6 1.2 1 0 0 1 1 1 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, MTCP1 PF08991.10 KFX88676.1 - 0.039 14.2 3.1 0.059 13.6 3.1 1.2 1 0 0 1 1 1 0 Mature-T-Cell Proliferation I type Hus1 PF04005.12 KFX88676.1 - 0.078 12.1 0.0 0.095 11.8 0.0 1.0 1 0 0 1 1 1 0 Hus1-like protein UBX PF00789.20 KFX88677.1 - 4.5e-14 52.4 0.0 8.7e-14 51.5 0.0 1.5 1 0 0 1 1 1 1 UBX domain CDC27 PF09507.10 KFX88677.1 - 0.21 10.9 15.9 0.32 10.4 15.9 1.2 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 VSG_B PF13206.6 KFX88677.1 - 0.27 10.4 10.9 0.39 9.9 10.9 1.1 1 0 0 1 1 1 0 Trypanosomal VSG domain DUF3807 PF12720.7 KFX88677.1 - 2.2 8.5 14.0 3.7 7.8 14.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3807) AAA_13 PF13166.6 KFX88677.1 - 9.2 4.8 10.6 12 4.3 10.6 1.1 1 0 0 1 1 1 0 AAA domain SURF1 PF02104.15 KFX88678.1 - 2.3e-45 155.0 0.1 8e-45 153.2 0.0 1.7 2 0 0 2 2 2 1 SURF1 family CENP-T_C PF15511.6 KFX88679.1 - 8.2e-45 151.4 0.4 2.1e-44 150.1 0.0 1.9 3 0 0 3 3 3 1 Centromere kinetochore component CENP-T histone fold CENP-S PF15630.6 KFX88679.1 - 5.9e-09 36.2 0.0 1.1e-08 35.3 0.0 1.4 1 0 0 1 1 1 1 CENP-S protein CBFD_NFYB_HMF PF00808.23 KFX88679.1 - 0.00017 21.8 0.0 0.00044 20.5 0.0 1.7 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 KFX88679.1 - 0.00024 21.4 0.0 0.00081 19.8 0.0 2.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Bromo_TP PF07524.13 KFX88679.1 - 0.14 12.2 0.0 0.24 11.4 0.0 1.3 1 0 0 1 1 1 0 Bromodomain associated 60KD_IMP PF02096.20 KFX88702.1 - 1.1e-09 38.4 0.0 1.6e-09 37.9 0.0 1.2 1 0 0 1 1 1 1 60Kd inner membrane protein ALG11_N PF15924.5 KFX88703.1 - 1.4e-83 280.0 0.1 2e-83 279.6 0.1 1.2 1 0 0 1 1 1 1 ALG11 mannosyltransferase N-terminus Glycos_transf_1 PF00534.20 KFX88703.1 - 7.3e-23 81.0 0.0 1.2e-22 80.2 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 KFX88703.1 - 3.1e-12 47.1 0.0 1.2e-11 45.1 0.0 1.9 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 KFX88703.1 - 0.0023 17.9 0.1 0.0044 17.0 0.1 1.5 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Phage_P2_GpE PF06528.12 KFX88703.1 - 0.23 11.0 3.0 3.1 7.4 0.5 2.4 2 0 0 2 2 2 0 Phage P2 GpE DUF5379 PF17350.2 KFX88703.1 - 0.55 10.5 4.5 0.3 11.4 1.6 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF5379) ATP-synt_Z PF16594.5 KFX88703.1 - 0.87 9.1 4.0 2.7 7.6 4.0 1.9 1 1 0 1 1 1 0 Putative AtpZ or ATP-synthase-associated Pkinase PF00069.25 KFX88706.1 - 5.5e-58 196.4 0.7 2.6e-56 190.9 0.7 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFX88706.1 - 2.7e-30 105.5 0.3 2.7e-28 99.0 0.0 2.1 1 1 1 2 2 2 2 Protein tyrosine kinase Haspin_kinase PF12330.8 KFX88706.1 - 0.00015 20.9 0.1 0.00024 20.2 0.1 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 KFX88706.1 - 0.0003 20.2 0.0 0.0005 19.5 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 KFX88706.1 - 0.00062 19.4 0.1 0.0013 18.4 0.1 1.5 1 1 0 1 1 1 1 RIO1 family APH PF01636.23 KFX88706.1 - 0.0014 18.6 0.0 0.0027 17.7 0.0 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KFX88706.1 - 0.0021 17.7 0.1 0.0033 17.0 0.1 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase Kinase-like PF14531.6 KFX88706.1 - 0.026 13.8 0.0 0.064 12.6 0.0 1.7 2 0 0 2 2 2 0 Kinase-like Pkinase_fungal PF17667.1 KFX88706.1 - 0.15 10.8 0.7 0.25 10.1 0.7 1.4 1 1 0 1 1 1 0 Fungal protein kinase SMC_N PF02463.19 KFX88708.1 - 3.9e-27 95.1 0.2 5.7e-27 94.6 0.2 1.2 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 KFX88708.1 - 1.5e-17 64.8 0.1 1.5e-17 64.8 0.1 4.7 3 2 2 5 5 5 1 AAA domain AAA_15 PF13175.6 KFX88708.1 - 2.1e-10 40.9 0.2 6.3e-07 29.4 0.0 2.6 2 1 0 2 2 2 1 AAA ATPase domain AAA_21 PF13304.6 KFX88708.1 - 3.5e-07 30.3 0.4 0.003 17.4 0.0 2.9 2 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 KFX88708.1 - 0.0004 20.1 0.0 0.0008 19.1 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA PF00004.29 KFX88708.1 - 0.06 13.8 0.0 0.3 11.5 0.0 2.3 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Vma12 PF11712.8 KFX88708.1 - 0.23 11.5 1.2 0.61 10.2 0.3 2.2 2 0 0 2 2 2 0 Endoplasmic reticulum-based factor for assembly of V-ATPase AAA_27 PF13514.6 KFX88708.1 - 0.23 11.0 0.0 0.23 11.0 0.0 3.5 4 1 0 4 4 4 0 AAA domain ABC_tran PF00005.27 KFX88708.1 - 0.53 10.8 0.0 0.53 10.8 0.0 4.6 3 2 1 4 4 4 0 ABC transporter Sec34 PF04136.15 KFX88708.1 - 0.63 9.9 17.1 0.15 11.9 1.1 4.8 3 2 1 4 4 4 0 Sec34-like family AAA_16 PF13191.6 KFX88708.1 - 0.69 10.3 0.0 0.69 10.3 0.0 3.3 3 1 0 3 3 3 0 AAA ATPase domain SelK_SelG PF10961.8 KFX88712.1 - 0.046 14.3 0.3 0.046 14.3 0.3 2.5 3 0 0 3 3 3 0 Selenoprotein SelK_SelG DUF4293 PF14126.6 KFX88712.1 - 0.23 11.7 5.1 0.068 13.4 2.1 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4293) DUF5337 PF17272.2 KFX88712.1 - 4.9 7.1 10.7 2.9 7.8 4.9 2.4 1 1 1 2 2 2 0 Family of unknown function (DUF5337) DUF2157 PF09925.9 KFX88712.1 - 6.3 6.6 11.5 9.2 6.0 5.2 2.2 1 1 1 2 2 2 0 Predicted membrane protein (DUF2157) Peptidase_M41 PF01434.18 KFX88714.1 - 6.4e-67 225.1 0.0 1.1e-66 224.4 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.29 KFX88714.1 - 4.7e-42 143.6 0.0 1.2e-41 142.2 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KFX88714.1 - 2.3e-12 46.5 0.1 6.4e-12 45.1 0.1 1.8 1 0 0 1 1 1 1 AAA+ lid domain APH PF01636.23 KFX88714.1 - 1.9e-08 34.5 0.1 1.3e-07 31.8 0.1 2.1 1 1 0 1 1 1 1 Phosphotransferase enzyme family FtsH_ext PF06480.15 KFX88714.1 - 1e-05 25.8 0.0 2.8e-05 24.4 0.0 1.7 1 0 0 1 1 1 1 FtsH Extracellular AAA_5 PF07728.14 KFX88714.1 - 0.00044 20.3 0.0 0.0011 19.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 KFX88714.1 - 0.0049 16.6 0.0 0.012 15.4 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 KFX88714.1 - 0.009 16.4 0.0 0.25 11.7 0.1 2.9 3 0 0 3 3 2 1 AAA ATPase domain AAA_22 PF13401.6 KFX88714.1 - 0.014 15.7 0.0 1.9 8.8 0.1 2.8 2 0 0 2 2 2 0 AAA domain TIP49 PF06068.13 KFX88714.1 - 0.017 14.3 0.1 0.031 13.5 0.1 1.3 1 0 0 1 1 1 0 TIP49 P-loop domain AAA_2 PF07724.14 KFX88714.1 - 0.035 14.2 0.0 0.12 12.5 0.0 1.9 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) Pex14_N PF04695.13 KFX88721.1 - 7.3e-08 33.2 0.9 7.3e-08 33.2 0.9 2.2 2 1 0 2 2 2 1 Peroxisomal membrane anchor protein (Pex14p) conserved region Ish1 PF10281.9 KFX88721.1 - 0.11 12.8 0.1 9.1 6.7 0.0 2.6 2 0 0 2 2 2 0 Putative stress-responsive nuclear envelope protein DUF1771 PF08590.10 KFX88737.1 - 4.4e-15 55.8 9.7 1.8e-14 53.8 9.7 2.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1771) zf_CCCH_4 PF18345.1 KFX88737.1 - 3e-09 36.6 6.5 4.9e-06 26.4 0.6 3.0 2 1 0 2 2 2 2 Zinc finger domain Smr PF01713.21 KFX88737.1 - 2.7e-07 30.8 0.0 8.5e-07 29.3 0.0 1.9 1 0 0 1 1 1 1 Smr domain zf-CCCH PF00642.24 KFX88737.1 - 2e-06 27.5 0.6 0.0061 16.4 0.1 2.4 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 KFX88737.1 - 2.5e-05 24.0 8.9 0.0023 17.7 0.4 3.2 2 1 0 2 2 2 2 CCCH-type zinc finger zf-CCCH_2 PF14608.6 KFX88737.1 - 0.00018 21.9 4.4 0.29 11.7 0.2 2.5 2 0 0 2 2 2 2 RNA-binding, Nab2-type zinc finger HBS1_N PF08938.10 KFX88737.1 - 0.011 16.0 0.0 0.031 14.6 0.0 1.7 1 0 0 1 1 1 0 HBS1 N-terminus Torus PF16131.5 KFX88737.1 - 0.078 13.7 2.9 2.1 9.1 0.6 2.5 1 1 1 2 2 2 0 Torus domain zf-CCCH_3 PF15663.5 KFX88737.1 - 0.11 12.8 5.1 3.7 7.8 0.6 2.4 1 1 1 2 2 2 0 Zinc-finger containing family SMN PF06003.12 KFX88740.1 - 1.2e-07 31.2 2.4 0.00031 20.1 0.3 2.2 2 0 0 2 2 2 2 Survival motor neuron protein (SMN) Copper-bind PF00127.20 KFX88741.1 - 0.0064 16.9 0.5 0.018 15.5 0.5 1.7 1 0 0 1 1 1 1 Copper binding proteins, plastocyanin/azurin family Cu_bind_like PF02298.17 KFX88741.1 - 0.01 15.8 0.4 0.048 13.7 0.4 2.0 1 1 0 1 1 1 0 Plastocyanin-like domain Syndecan PF01034.20 KFX88742.1 - 0.18 11.8 0.4 0.18 11.8 0.4 1.7 2 0 0 2 2 2 0 Syndecan domain DUF4282 PF14110.6 KFX88742.1 - 4.8 8.0 12.3 15 6.4 4.9 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4282) Guanylate_kin PF00625.21 KFX88743.1 - 8e-56 188.6 0.1 1.2e-55 188.0 0.1 1.3 1 0 0 1 1 1 1 Guanylate kinase DEAD PF00270.29 KFX88743.1 - 2e-09 37.4 0.3 6.8e-09 35.7 0.1 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_18 PF13238.6 KFX88743.1 - 8.3e-05 23.1 0.1 0.00027 21.5 0.1 1.9 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.6 KFX88743.1 - 0.0012 19.1 0.0 0.0035 17.6 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.6 KFX88743.1 - 0.0042 17.3 0.1 0.17 12.1 0.1 2.3 1 1 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 KFX88743.1 - 0.0055 16.6 0.0 0.019 14.9 0.0 1.9 1 0 0 1 1 1 1 RsgA GTPase AAA PF00004.29 KFX88743.1 - 0.023 15.1 0.1 0.081 13.4 0.1 2.1 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 KFX88743.1 - 0.027 14.6 0.2 0.38 10.9 0.2 2.6 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.6 KFX88743.1 - 0.038 14.4 0.1 0.12 12.8 0.1 2.1 1 1 0 1 1 1 0 AAA ATPase domain Rad17 PF03215.15 KFX88743.1 - 0.085 12.8 0.0 0.16 11.9 0.0 1.4 1 0 0 1 1 1 0 Rad17 P-loop domain MMR_HSR1 PF01926.23 KFX88743.1 - 0.093 12.8 0.2 0.28 11.3 0.0 2.0 2 1 0 2 2 2 0 50S ribosome-binding GTPase Thymidylate_kin PF02223.17 KFX88743.1 - 0.11 12.2 0.5 0.91 9.2 0.5 2.1 1 1 0 1 1 1 0 Thymidylate kinase dNK PF01712.19 KFX88743.1 - 0.13 12.1 0.0 0.85 9.4 0.0 2.1 2 0 0 2 2 2 0 Deoxynucleoside kinase ABC_tran PF00005.27 KFX88743.1 - 0.13 12.7 0.2 0.32 11.5 0.2 1.8 1 1 0 1 1 1 0 ABC transporter FMN_red PF03358.15 KFX88752.1 - 4.3e-09 36.3 0.0 6e-09 35.8 0.0 1.1 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.17 KFX88752.1 - 0.00034 20.4 0.0 0.00044 20.0 0.0 1.1 1 0 0 1 1 1 1 Flavodoxin-like fold Flavodoxin_1 PF00258.25 KFX88752.1 - 0.0023 18.2 0.1 0.0056 16.9 0.1 1.8 1 1 0 1 1 1 1 Flavodoxin C2 PF00168.30 KFX88759.1 - 3e-16 59.6 0.0 4.9e-16 58.9 0.0 1.3 1 0 0 1 1 1 1 C2 domain ICL PF00463.21 KFX88760.1 - 1.5e-292 970.8 1.2 1.7e-292 970.6 1.2 1.0 1 0 0 1 1 1 1 Isocitrate lyase family PEP_mutase PF13714.6 KFX88760.1 - 3.9e-11 42.9 0.1 1.1e-10 41.3 0.0 1.8 2 0 0 2 2 2 1 Phosphoenolpyruvate phosphomutase Mus7 PF09462.10 KFX88762.1 - 2.5e-57 195.1 0.0 3.4e-57 194.7 0.0 1.2 1 0 0 1 1 1 1 Mus7/MMS22 family PHO4 PF01384.20 KFX88762.1 - 0.058 12.4 0.0 0.088 11.8 0.0 1.2 1 0 0 1 1 1 0 Phosphate transporter family Cys_Met_Meta_PP PF01053.20 KFX88763.1 - 3.4e-56 190.4 0.0 7e-56 189.4 0.0 1.5 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.21 KFX88763.1 - 0.00036 19.8 0.0 0.00088 18.5 0.0 1.6 1 1 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 KFX88763.1 - 0.045 12.7 0.0 0.074 12.0 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class-V FMN_bind_2 PF04299.12 KFX88764.1 - 3.2e-57 192.9 0.0 3.9e-57 192.6 0.0 1.1 1 0 0 1 1 1 1 Putative FMN-binding domain Fungal_trans_2 PF11951.8 KFX88765.1 - 5.9e-46 157.0 6.1 7.3e-46 156.7 6.1 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Swi3 PF07962.12 KFX88777.1 - 9.8e-31 105.6 0.1 1.4e-30 105.1 0.1 1.2 1 0 0 1 1 1 1 Replication Fork Protection Component Swi3 TPP_enzyme_N PF02776.18 KFX88782.1 - 3e-37 127.9 0.0 1.5e-36 125.6 0.0 2.0 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.21 KFX88782.1 - 9.5e-21 74.2 0.1 8.3e-20 71.1 0.0 2.3 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.22 KFX88782.1 - 5.3e-11 42.4 0.0 1e-10 41.4 0.0 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain Gpr1_Fun34_YaaH PF01184.19 KFX88798.1 - 6.2e-95 316.7 17.2 7.3e-95 316.4 17.2 1.0 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family Cyclin_N PF00134.23 KFX88799.1 - 7.7e-35 119.4 0.2 1.6e-34 118.4 0.2 1.6 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 KFX88799.1 - 7.2e-13 48.7 0.3 1.8e-12 47.4 0.3 1.7 1 1 0 1 1 1 1 Cyclin, C-terminal domain Isochorismatase PF00857.20 KFX88804.1 - 1.4e-32 113.3 0.0 1.5e-32 113.2 0.0 1.0 1 0 0 1 1 1 1 Isochorismatase family MFS_1 PF07690.16 KFX88805.1 - 5e-49 167.1 14.8 5e-49 167.1 14.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KFX88805.1 - 4.5e-11 42.3 23.2 6.2e-11 41.8 6.6 3.0 3 0 0 3 3 3 2 Sugar (and other) transporter MFS_3 PF05977.13 KFX88805.1 - 3.9e-05 22.2 2.6 3.9e-05 22.2 2.6 1.7 2 0 0 2 2 2 1 Transmembrane secretion effector MFS_5 PF05631.14 KFX88805.1 - 0.0015 17.5 3.5 0.002 17.1 0.7 2.3 3 0 0 3 3 3 1 Sugar-tranasporters, 12 TM MFS_1_like PF12832.7 KFX88805.1 - 0.49 9.2 10.1 0.2 10.5 1.2 3.1 2 1 2 4 4 4 0 MFS_1 like family MFS_1 PF07690.16 KFX88806.1 - 1.4e-35 122.9 33.9 3.8e-34 118.2 32.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Acatn PF13000.7 KFX88806.1 - 5.8 5.3 7.7 0.22 10.0 1.1 1.9 3 0 0 3 3 3 0 Acetyl-coenzyme A transporter 1 Snf7 PF03357.21 KFX88808.1 - 1.6e-06 27.8 0.2 2.2e-06 27.4 0.1 1.3 1 1 0 1 1 1 1 Snf7 bPH_2 PF03703.14 KFX88808.1 - 0.1 12.8 0.3 1.6 9.0 0.1 2.5 1 1 1 2 2 2 0 Bacterial PH domain DSHCT PF08148.12 KFX88809.1 - 3.1e-50 170.1 0.7 1e-49 168.3 0.6 2.0 2 0 0 2 2 2 1 DSHCT (NUC185) domain Ski2_N PF17911.1 KFX88809.1 - 3e-39 133.9 0.0 1e-38 132.2 0.0 1.9 2 0 0 2 2 2 1 Ski2 N-terminal region rRNA_proc-arch PF13234.6 KFX88809.1 - 3.2e-22 79.7 0.0 5.4e-22 79.0 0.0 1.4 1 0 0 1 1 1 1 rRNA-processing arch domain DEAD PF00270.29 KFX88809.1 - 1.6e-18 67.1 0.0 3.8e-18 65.9 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KFX88809.1 - 6e-07 29.8 0.0 3.2e-06 27.4 0.0 2.2 1 1 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KFX88809.1 - 1.1e-05 25.5 0.0 2.1e-05 24.6 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 KFX88809.1 - 0.08 13.2 0.0 0.33 11.2 0.0 2.0 1 0 0 1 1 1 0 AAA domain CHCH PF06747.13 KFX88810.1 - 9.8e-10 38.3 11.5 2.8e-08 33.7 2.2 2.6 3 0 0 3 3 3 2 CHCH domain CX9C PF16860.5 KFX88810.1 - 6.7e-06 26.0 4.9 0.00041 20.3 1.2 2.2 2 0 0 2 2 2 2 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, TF_Otx PF03529.13 KFX88810.1 - 0.15 12.5 1.0 0.24 11.8 1.0 1.4 1 0 0 1 1 1 0 Otx1 transcription factor Cmc1 PF08583.10 KFX88810.1 - 0.48 10.5 10.6 3.8 7.6 2.3 2.4 1 1 1 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like COX6B PF02297.17 KFX88810.1 - 3.5 7.9 10.2 11 6.4 2.6 2.2 1 1 1 2 2 2 0 Cytochrome oxidase c subunit VIb UCR_hinge PF02320.16 KFX88810.1 - 8.6 6.6 7.5 62 3.9 5.8 2.7 1 1 1 2 2 2 0 Ubiquinol-cytochrome C reductase hinge protein Fungal_trans PF04082.18 KFX88812.1 - 3.5e-28 98.4 0.0 5.5e-28 97.7 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KFX88812.1 - 1.7e-09 37.6 10.9 2.9e-09 36.9 10.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Dynamin_N PF00350.23 KFX88815.1 - 5.7e-33 114.3 0.0 1.3e-32 113.2 0.0 1.6 1 0 0 1 1 1 1 Dynamin family Dynamin_M PF01031.20 KFX88815.1 - 2.3e-26 92.7 1.2 4.3e-26 91.8 1.2 1.5 1 0 0 1 1 1 1 Dynamin central region MMR_HSR1 PF01926.23 KFX88815.1 - 0.0005 20.1 0.0 0.0023 18.0 0.0 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_21 PF13304.6 KFX88815.1 - 0.0039 17.1 0.0 0.57 9.9 0.0 2.5 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 KFX88815.1 - 0.063 13.0 0.7 0.26 10.9 0.0 2.1 2 1 0 2 2 2 0 AAA ATPase domain GED PF02212.18 KFX88815.1 - 0.096 12.8 0.1 0.35 11.0 0.1 2.0 1 0 0 1 1 1 0 Dynamin GTPase effector domain Nucleoporin_FG PF13634.6 KFX88815.1 - 1.2 10.0 11.7 2.3 9.1 11.7 1.4 1 0 0 1 1 1 0 Nucleoporin FG repeat region Glyco_hydro_5_C PF18564.1 KFX88816.1 - 4.4e-24 84.8 0.0 1.1e-23 83.5 0.0 1.7 1 0 0 1 1 1 1 Glycoside hydrolase family 5 C-terminal domain Cellulase PF00150.18 KFX88816.1 - 1.5e-14 54.1 2.4 3.7e-09 36.4 0.6 2.8 2 1 0 2 2 2 2 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_35 PF01301.19 KFX88816.1 - 0.072 12.7 0.3 0.14 11.7 0.3 1.4 1 0 0 1 1 1 0 Glycosyl hydrolases family 35 TPR_16 PF13432.6 KFX88817.1 - 9.1e-36 122.2 38.6 1.9e-07 31.6 4.8 12.9 10 2 3 13 13 12 8 Tetratricopeptide repeat TPR_2 PF07719.17 KFX88817.1 - 7.6e-33 110.0 40.1 0.0067 16.5 0.0 16.1 17 0 0 17 17 15 10 Tetratricopeptide repeat TPR_19 PF14559.6 KFX88817.1 - 3.1e-26 91.7 20.0 0.0025 18.3 4.2 10.6 10 1 1 11 11 11 6 Tetratricopeptide repeat TPR_14 PF13428.6 KFX88817.1 - 2.7e-25 86.9 36.8 0.039 14.8 0.1 15.7 12 6 5 17 17 16 6 Tetratricopeptide repeat TPR_8 PF13181.6 KFX88817.1 - 5.6e-25 85.4 20.1 0.13 12.5 0.0 15.0 17 0 0 17 17 16 7 Tetratricopeptide repeat TPR_1 PF00515.28 KFX88817.1 - 6.1e-25 86.0 23.4 0.0011 18.7 0.0 13.6 13 0 0 13 13 13 6 Tetratricopeptide repeat TPR_17 PF13431.6 KFX88817.1 - 2.4e-24 83.9 14.1 0.1 13.0 0.0 14.9 16 0 0 16 16 15 5 Tetratricopeptide repeat TPR_11 PF13414.6 KFX88817.1 - 3.3e-20 71.5 15.3 0.00046 19.8 0.0 9.7 11 0 0 11 11 11 4 TPR repeat TPR_12 PF13424.6 KFX88817.1 - 8.3e-20 70.9 32.5 9.2e-05 22.7 0.1 13.0 9 3 5 14 14 13 3 Tetratricopeptide repeat TPR_9 PF13371.6 KFX88817.1 - 5.4e-14 52.1 11.7 6.8e-05 22.9 0.0 7.1 7 0 0 7 7 6 4 Tetratricopeptide repeat TPR_6 PF13174.6 KFX88817.1 - 4.8e-11 42.6 21.9 0.05 14.3 0.0 12.5 15 0 0 15 15 12 2 Tetratricopeptide repeat TPR_7 PF13176.6 KFX88817.1 - 2e-09 36.8 16.3 0.34 11.0 0.0 11.4 12 0 0 12 12 11 2 Tetratricopeptide repeat TPR_20 PF14561.6 KFX88817.1 - 7e-06 26.3 8.6 2.5 8.5 0.0 7.5 6 2 1 8 8 8 1 Tetratricopeptide repeat ANAPC3 PF12895.7 KFX88817.1 - 4.8e-05 23.5 12.4 7.2 6.9 0.1 6.8 6 0 0 6 6 6 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_22 PF18833.1 KFX88817.1 - 0.00014 21.9 0.1 0.00035 20.7 0.1 1.7 1 0 0 1 1 1 1 Tetratricopeptide repeat ChAPs PF09295.10 KFX88817.1 - 0.0031 16.6 0.2 9.7 5.1 0.0 4.3 4 0 0 4 4 4 0 ChAPs (Chs5p-Arf1p-binding proteins) DUF2225 PF09986.9 KFX88817.1 - 0.011 15.5 0.6 4.8 6.8 0.1 2.7 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2225) FAT PF02259.23 KFX88817.1 - 0.025 13.8 7.0 1.9 7.6 0.7 4.7 4 1 0 5 5 5 0 FAT domain Coatomer_WDAD PF04053.14 KFX88817.1 - 0.038 13.0 1.3 0.05 12.6 0.0 1.8 2 0 0 2 2 2 0 Coatomer WD associated region Tcf25 PF04910.14 KFX88817.1 - 0.078 12.0 0.0 2.3 7.2 0.0 2.8 3 0 0 3 3 3 0 Transcriptional repressor TCF25 Sel1 PF08238.12 KFX88817.1 - 0.35 11.6 4.5 3.4 8.5 0.0 4.4 4 1 0 4 4 4 0 Sel1 repeat TOM20_plant PF06552.12 KFX88817.1 - 1.9 8.2 8.3 3.9 7.2 0.0 4.4 5 0 0 5 5 5 0 Plant specific mitochondrial import receptor subunit TOM20 Adaptin_N PF01602.20 KFX88818.1 - 1.1e-139 466.4 4.0 1.5e-139 465.9 4.0 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 KFX88818.1 - 4.3e-62 208.9 5.8 4.6e-60 202.3 0.5 2.9 2 1 0 2 2 2 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 KFX88818.1 - 2.1e-18 66.5 0.8 1.2e-06 28.8 0.0 5.0 2 2 4 6 6 6 5 HEAT repeats HEAT PF02985.22 KFX88818.1 - 3.8e-11 42.2 4.7 0.023 14.9 0.0 6.9 9 0 0 9 9 9 3 HEAT repeat HEAT_EZ PF13513.6 KFX88818.1 - 0.00042 20.8 0.2 0.28 11.7 0.0 4.7 4 1 1 5 5 5 1 HEAT-like repeat CLASP_N PF12348.8 KFX88818.1 - 0.0013 18.3 0.1 1.9 8.0 0.0 3.4 2 1 1 3 3 3 2 CLASP N terminal UNC45-central PF11701.8 KFX88818.1 - 0.0037 17.2 0.2 2.3 8.1 0.1 2.9 2 1 0 2 2 2 2 Myosin-binding striated muscle assembly central Arm PF00514.23 KFX88818.1 - 0.03 14.3 0.6 8.5 6.6 0.0 4.6 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat Atx10homo_assoc PF09759.9 KFX88818.1 - 0.074 13.1 0.0 7.5 6.7 0.0 3.4 2 0 0 2 2 2 0 Spinocerebellar ataxia type 10 protein domain DUF5578 PF17741.1 KFX88818.1 - 2.6 7.4 4.8 19 4.6 0.1 2.9 3 0 0 3 3 3 0 Family of unknown function (DUF5578) AGP PF06376.12 KFX88819.1 - 0.097 12.5 1.0 0.22 11.4 1.0 1.6 1 0 0 1 1 1 0 Arabinogalactan peptide DUF5310 PF17237.2 KFX88820.1 - 7.2e-21 73.8 1.6 1.2e-20 73.1 1.6 1.4 1 0 0 1 1 1 1 Family of unknown function (DUF5310) Pro_CA PF00484.19 KFX88821.1 - 1.6e-15 57.8 0.0 2.9e-15 56.9 0.0 1.4 1 1 0 1 1 1 1 Carbonic anhydrase BolA PF01722.18 KFX88822.1 - 4.9e-18 65.2 0.0 1.2e-17 63.9 0.0 1.6 1 1 0 1 1 1 1 BolA-like protein NIF3 PF01784.18 KFX88823.1 - 5.2e-57 193.3 0.0 6.5e-57 193.0 0.0 1.1 1 0 0 1 1 1 1 NIF3 (NGG1p interacting factor 3) Vps51 PF08700.11 KFX88824.1 - 6.2e-28 96.7 1.0 1e-27 96.0 0.1 1.8 2 0 0 2 2 2 1 Vps51/Vps67 Dor1 PF04124.12 KFX88824.1 - 4.6e-08 32.1 2.0 6.8e-08 31.6 2.0 1.1 1 0 0 1 1 1 1 Dor1-like family COG5 PF10392.9 KFX88824.1 - 0.0051 17.0 0.2 0.017 15.3 0.0 1.8 1 1 1 2 2 2 1 Golgi transport complex subunit 5 BBP1_C PF15272.6 KFX88824.1 - 0.028 14.2 0.5 0.045 13.6 0.3 1.4 1 1 0 1 1 1 0 Spindle pole body component BBP1, C-terminal DUF365 PF04033.12 KFX88824.1 - 0.059 13.6 0.0 0.12 12.6 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF365) Ntox1 PF15500.6 KFX88824.1 - 2.5 8.5 5.3 9.9 6.6 0.0 2.5 1 1 1 2 2 2 0 Putative RNase-like toxin, toxin_1 FUSC PF04632.12 KFX88824.1 - 2.8 6.4 6.4 4.5 5.7 6.4 1.3 1 1 0 1 1 1 0 Fusaric acid resistance protein family RMI1_N PF08585.12 KFX88825.1 - 3.5e-47 161.0 0.0 4.3e-47 160.7 0.0 1.1 1 0 0 1 1 1 1 RecQ mediated genome instability protein Xpo1 PF08389.12 KFX88826.1 - 1.6e-07 31.5 0.6 4.2e-05 23.7 0.1 2.8 2 0 0 2 2 2 2 Exportin 1-like protein HTH_Tnp_Tc5 PF03221.16 KFX88826.1 - 0.059 13.4 0.2 18 5.4 0.3 2.7 2 0 0 2 2 2 0 Tc5 transposase DNA-binding domain IBN_N PF03810.19 KFX88826.1 - 0.12 12.3 0.0 0.36 10.8 0.0 1.9 1 0 0 1 1 1 0 Importin-beta N-terminal domain TLD PF07534.16 KFX88827.1 - 7.7e-26 91.0 0.0 3.3e-14 53.3 0.0 2.2 2 0 0 2 2 2 2 TLD Evr1_Alr PF04777.13 KFX88827.1 - 0.0014 19.0 0.0 0.0031 18.0 0.0 1.5 1 0 0 1 1 1 1 Erv1 / Alr family AAA PF00004.29 KFX88828.1 - 4e-40 137.3 0.0 8.9e-40 136.2 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) PRKCSH PF07915.13 KFX88828.1 - 7.9e-16 58.8 0.1 7.9e-16 58.8 0.1 2.1 2 0 0 2 2 1 1 Glucosidase II beta subunit-like protein AAA_lid_3 PF17862.1 KFX88828.1 - 2.1e-06 27.4 0.0 6e-06 26.0 0.0 1.7 1 0 0 1 1 1 1 AAA+ lid domain AAA_5 PF07728.14 KFX88828.1 - 0.00037 20.5 0.0 0.0017 18.4 0.0 2.1 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 KFX88828.1 - 0.0008 19.8 0.3 0.041 14.3 0.0 3.2 3 1 0 4 4 3 1 AAA ATPase domain AAA_22 PF13401.6 KFX88828.1 - 0.00086 19.6 0.0 0.012 15.9 0.0 2.4 1 1 0 1 1 1 1 AAA domain AAA_2 PF07724.14 KFX88828.1 - 0.001 19.2 0.0 0.003 17.7 0.0 1.7 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) DUF815 PF05673.13 KFX88828.1 - 0.0054 15.9 0.0 0.0098 15.1 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) RuvB_N PF05496.12 KFX88828.1 - 0.025 14.3 0.0 0.05 13.3 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain PRKCSH_1 PF13015.6 KFX88828.1 - 0.044 13.5 0.0 12 5.5 0.1 2.6 2 0 0 2 2 2 0 Glucosidase II beta subunit-like protein AAA_28 PF13521.6 KFX88828.1 - 0.083 13.1 0.0 0.19 12.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 KFX88828.1 - 0.13 12.4 0.0 0.28 11.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 KFX88828.1 - 0.13 11.7 0.0 0.3 10.6 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region Cpn60_TCP1 PF00118.24 KFX88829.1 - 8.5e-151 502.9 18.1 9.6e-151 502.7 18.1 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family WD40 PF00400.32 KFX88832.1 - 1.2e-47 158.9 24.6 1.3e-08 35.3 0.1 8.9 9 0 0 9 9 9 7 WD domain, G-beta repeat F-box-like PF12937.7 KFX88832.1 - 8.1e-12 44.8 0.3 1.7e-11 43.8 0.3 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KFX88832.1 - 2.3e-10 40.1 0.5 7.7e-10 38.4 0.2 2.0 1 1 1 2 2 2 1 F-box domain Nup160 PF11715.8 KFX88832.1 - 2.1e-09 36.6 5.5 0.23 10.0 0.1 5.6 3 1 3 6 6 6 4 Nucleoporin Nup120/160 ANAPC4_WD40 PF12894.7 KFX88832.1 - 6.3e-09 36.0 0.1 0.044 14.1 0.0 5.2 2 2 3 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain F-box_4 PF15966.5 KFX88832.1 - 0.0018 18.1 0.3 0.0063 16.4 0.1 2.1 2 0 0 2 2 2 1 F-box PRANC PF09372.10 KFX88832.1 - 0.23 11.8 0.0 0.4 11.0 0.0 1.3 1 0 0 1 1 1 0 PRANC domain Peptidase_M14 PF00246.24 KFX88833.1 - 3.8e-71 240.3 0.0 5.1e-71 239.8 0.0 1.2 1 0 0 1 1 1 1 Zinc carboxypeptidase Glyco_hydro_65N PF03636.15 KFX88841.1 - 9.9e-32 110.4 0.0 2.2e-31 109.3 0.0 1.5 2 0 0 2 2 2 1 Glycosyl hydrolase family 65, N-terminal domain Glyco_hydro_65m PF03632.15 KFX88841.1 - 4.7e-28 98.1 7.7 1.3e-24 86.8 2.1 2.4 1 1 1 2 2 2 2 Glycosyl hydrolase family 65 central catalytic domain RhoGEF PF00621.20 KFX88843.1 - 1.1e-23 84.5 0.0 2.2e-23 83.4 0.0 1.5 1 0 0 1 1 1 1 RhoGEF domain DUF3507 PF12015.8 KFX88843.1 - 0.0056 16.4 0.0 0.011 15.5 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3507) Nod1 PF17114.5 KFX88843.1 - 0.036 14.2 0.0 0.069 13.3 0.0 1.5 1 0 0 1 1 1 0 Gef2-related medial cortical node protein Nod1 Dcc1 PF09724.9 KFX88844.1 - 2.6e-10 40.1 0.0 2.7e-10 40.1 0.0 1.1 1 0 0 1 1 1 1 Sister chromatid cohesion protein Dcc1 cobW PF02492.19 KFX88848.1 - 0.00052 19.6 0.0 0.00062 19.4 0.0 1.1 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain Arf PF00025.21 KFX88848.1 - 0.00068 19.1 0.4 0.004 16.6 0.4 2.3 1 1 0 1 1 1 1 ADP-ribosylation factor family Zea_mays_MuDR PF05928.11 KFX88848.1 - 0.069 12.8 0.0 0.093 12.4 0.0 1.3 1 0 0 1 1 1 0 Zea mays MURB-like protein (MuDR) DUF4479 PF14794.6 KFX88848.1 - 0.16 11.8 0.0 0.45 10.4 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4479) Helo_like_N PF17111.5 KFX88855.1 - 0.048 13.0 0.0 0.069 12.5 0.0 1.2 1 0 0 1 1 1 0 Fungal N-terminal domain of STAND proteins OrsD PF12013.8 KFX88855.1 - 0.16 12.4 0.0 0.53 10.7 0.0 1.8 2 0 0 2 2 2 0 Orsellinic acid/F9775 biosynthesis cluster protein D Lge1 PF11488.8 KFX88858.1 - 0.12 12.6 0.0 13 6.0 0.0 2.4 2 0 0 2 2 2 0 Transcriptional regulatory protein LGE1 HflK_N PF12221.8 KFX88858.1 - 0.12 12.4 0.2 0.66 10.0 0.1 2.3 3 0 0 3 3 3 0 Bacterial membrane protein N terminal Acyl-CoA_dh_2 PF08028.11 KFX88858.1 - 0.21 11.9 3.1 1.5 9.1 0.1 2.2 2 0 0 2 2 2 0 Acyl-CoA dehydrogenase, C-terminal domain ThiF PF00899.21 KFX88859.1 - 1.3e-30 106.5 0.0 1.8e-30 106.1 0.0 1.1 1 0 0 1 1 1 1 ThiF family DUF2431 PF10354.9 KFX88860.1 - 8.3e-66 221.4 0.0 1.1e-65 221.1 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF2431) F-box PF00646.33 KFX88864.1 - 2.1e-07 30.6 0.1 4.7e-07 29.5 0.1 1.5 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 KFX88864.1 - 2.6e-05 24.0 0.2 0.0001 22.1 0.0 2.1 2 0 0 2 2 2 1 F-box-like V-ATPase_C PF03223.15 KFX88867.1 - 2.8e-124 415.3 0.0 3.1e-124 415.1 0.0 1.0 1 0 0 1 1 1 1 V-ATPase subunit C APS_kinase PF01583.20 KFX88868.1 - 5.3e-68 227.9 0.0 6.4e-68 227.6 0.0 1.1 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_33 PF13671.6 KFX88868.1 - 0.00019 21.6 0.0 0.00028 21.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 KFX88868.1 - 0.00038 21.0 0.0 0.00049 20.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain KTI12 PF08433.10 KFX88868.1 - 0.0016 18.0 0.0 0.0024 17.3 0.0 1.3 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_29 PF13555.6 KFX88868.1 - 0.041 13.6 0.0 0.072 12.8 0.0 1.3 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_16 PF13191.6 KFX88868.1 - 0.081 13.3 0.1 0.1 13.0 0.1 1.3 1 1 0 1 1 1 0 AAA ATPase domain CPT PF07931.12 KFX88868.1 - 0.09 12.6 0.0 0.19 11.6 0.0 1.7 1 1 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein DUF463 PF04317.12 KFX88868.1 - 0.1 11.5 0.0 0.13 11.2 0.0 1.2 1 0 0 1 1 1 0 YcjX-like family, DUF463 Zeta_toxin PF06414.12 KFX88868.1 - 0.11 11.7 0.0 0.16 11.3 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin 6PF2K PF01591.18 KFX88868.1 - 0.14 11.4 0.0 0.22 10.8 0.0 1.3 1 0 0 1 1 1 0 6-phosphofructo-2-kinase G-alpha PF00503.20 KFX88868.1 - 0.15 11.2 0.1 0.3 10.2 0.1 1.4 1 1 0 1 1 1 0 G-protein alpha subunit Abhydrolase_3 PF07859.13 KFX88869.1 - 6.5e-05 22.9 0.0 7.7e-05 22.6 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 KFX88869.1 - 0.0031 16.4 0.0 0.0032 16.4 0.0 1.1 1 0 0 1 1 1 1 Steryl acetyl hydrolase Abhydrolase_3 PF07859.13 KFX88870.1 - 0.0012 18.7 0.0 0.0018 18.1 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 KFX88870.1 - 0.021 13.7 0.0 0.027 13.4 0.0 1.1 1 0 0 1 1 1 0 Steryl acetyl hydrolase L31 PF09784.9 KFX88871.1 - 0.054 13.9 0.1 1.1 9.7 0.1 2.5 2 0 0 2 2 2 0 Mitochondrial ribosomal protein L31 Transferase PF02458.15 KFX88871.1 - 0.08 11.6 0.0 0.25 10.0 0.0 1.8 1 1 0 1 1 1 0 Transferase family Lipase_GDSL_2 PF13472.6 KFX88872.1 - 3.5e-18 66.6 0.1 7.8e-18 65.5 0.1 1.6 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 KFX88872.1 - 5e-07 29.9 0.0 7.7e-07 29.3 0.0 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase VCBS PF13517.6 KFX88872.1 - 3.4e-06 27.6 15.5 2.3e-05 24.9 5.6 3.1 1 1 1 2 2 2 2 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella OSK PF17182.4 KFX88872.1 - 0.0005 19.4 0.0 0.00074 18.8 0.0 1.2 1 0 0 1 1 1 1 OSK domain FG-GAP PF01839.23 KFX88872.1 - 3.1 8.0 9.7 18 5.5 0.3 3.2 2 0 0 2 2 2 0 FG-GAP repeat HATPase_c PF02518.26 KFX88874.1 - 1.2e-30 106.3 0.0 4.4e-30 104.5 0.0 2.0 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 KFX88874.1 - 2.8e-21 75.8 0.1 1.1e-20 73.9 0.1 2.1 2 0 0 2 2 2 1 Response regulator receiver domain HisKA PF00512.25 KFX88874.1 - 4.7e-20 71.4 0.7 3.6e-19 68.6 0.2 2.7 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain AAA_16 PF13191.6 KFX88874.1 - 1e-15 58.5 0.1 6.7e-15 55.9 0.1 2.4 2 0 0 2 2 2 1 AAA ATPase domain GAF_2 PF13185.6 KFX88874.1 - 7e-11 42.6 0.0 2.7e-10 40.7 0.0 2.1 1 0 0 1 1 1 1 GAF domain Pkinase PF00069.25 KFX88874.1 - 5.4e-07 29.2 0.0 1.3e-06 28.0 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain GAF PF01590.26 KFX88874.1 - 0.00019 22.1 0.0 0.00053 20.6 0.0 1.8 1 0 0 1 1 1 1 GAF domain NACHT PF05729.12 KFX88874.1 - 0.0043 17.0 0.0 2.7 7.9 0.0 2.5 2 0 0 2 2 2 2 NACHT domain HATPase_c_3 PF13589.6 KFX88874.1 - 0.0098 15.7 0.0 0.023 14.5 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase GAF_3 PF13492.6 KFX88874.1 - 0.1 13.0 0.0 0.3 11.4 0.0 1.8 1 0 0 1 1 1 0 GAF domain MeaB PF03308.16 KFX88874.1 - 0.12 11.3 0.1 0.23 10.4 0.1 1.4 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Pkinase_Tyr PF07714.17 KFX88874.1 - 0.14 11.5 0.0 0.25 10.6 0.0 1.3 1 0 0 1 1 1 0 Protein tyrosine kinase Cript PF10235.9 KFX88884.1 - 6.3e-19 68.3 8.1 6.3e-19 68.3 8.1 1.4 2 0 0 2 2 2 1 Microtubule-associated protein CRIPT DZR PF12773.7 KFX88884.1 - 0.0019 18.2 8.7 0.003 17.5 4.2 2.3 2 0 0 2 2 2 1 Double zinc ribbon zinc_ribbon_2 PF13240.6 KFX88884.1 - 4.3 7.2 12.6 1.8 8.4 1.4 3.3 2 1 2 4 4 4 0 zinc-ribbon domain Fungal_trans PF04082.18 KFX88888.1 - 4.3e-11 42.3 0.1 7.6e-11 41.5 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KFX88888.1 - 7.2e-10 38.8 9.8 1.2e-09 38.2 9.8 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain V_ATPase_I PF01496.19 KFX88891.1 - 0 1061.5 0.0 0 1061.2 0.0 1.0 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family Prenyltransf PF01255.19 KFX88891.1 - 6.4e-79 264.6 0.0 2.1e-78 262.9 0.0 1.8 2 0 0 2 2 2 1 Putative undecaprenyl diphosphate synthase Filament PF00038.21 KFX88891.1 - 0.045 13.3 4.4 2.9 7.4 0.1 2.5 2 1 0 2 2 2 0 Intermediate filament protein DivIC PF04977.15 KFX88891.1 - 0.067 13.0 0.2 0.45 10.3 0.2 2.4 1 0 0 1 1 1 0 Septum formation initiator DASH_Dam1 PF08653.10 KFX88891.1 - 0.08 12.8 0.5 15 5.5 0.1 3.9 4 0 0 4 4 4 0 DASH complex subunit Dam1 DUF4988 PF16378.5 KFX88891.1 - 0.14 11.8 0.1 0.35 10.5 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function Baculo_PEP_C PF04513.12 KFX88891.1 - 0.3 11.1 1.3 4.8 7.2 0.1 2.6 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus HMMR_N PF15905.5 KFX88891.1 - 0.36 10.2 1.9 2 7.8 0.1 2.1 2 0 0 2 2 2 0 Hyaluronan mediated motility receptor N-terminal CENP-F_leu_zip PF10473.9 KFX88891.1 - 1.5 8.9 4.1 1.9 8.5 0.9 2.2 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 FAM184 PF15665.5 KFX88891.1 - 3.2 7.5 4.0 1.9 8.2 1.1 1.9 2 0 0 2 2 2 0 Family with sequence similarity 184, A and B Atg14 PF10186.9 KFX88891.1 - 6.1 5.8 5.8 0.75 8.8 0.9 1.8 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 Rhomboid PF01694.22 KFX88892.1 - 9.8e-06 25.6 1.6 1.8e-05 24.8 1.6 1.3 1 0 0 1 1 1 1 Rhomboid family DUF1751 PF08551.10 KFX88892.1 - 0.00013 22.4 0.2 0.00026 21.5 0.2 1.5 1 0 0 1 1 1 1 Eukaryotic integral membrane protein (DUF1751) Sulfate_transp PF00916.20 KFX88892.1 - 0.04 12.7 0.9 0.049 12.4 0.3 1.4 2 0 0 2 2 2 0 Sulfate permease family Gly-zipper_Omp PF13488.6 KFX88892.1 - 0.07 13.1 0.3 0.18 11.9 0.3 1.6 1 0 0 1 1 1 0 Glycine zipper ING PF12998.7 KFX88893.1 - 6.6e-10 39.5 0.1 0.0005 20.6 0.0 2.3 2 0 0 2 2 2 2 Inhibitor of growth proteins N-terminal histone-binding DPBB_1 PF03330.18 KFX88893.1 - 1.4e-06 28.5 0.0 4.1e-06 27.0 0.0 1.9 1 0 0 1 1 1 1 Lytic transglycolase PHD PF00628.29 KFX88893.1 - 0.00088 19.1 6.4 0.0018 18.1 6.4 1.5 1 0 0 1 1 1 1 PHD-finger Barwin PF00967.17 KFX88893.1 - 0.0066 16.3 0.2 0.021 14.7 0.2 1.8 1 0 0 1 1 1 1 Barwin family zf-HC5HC2H PF13771.6 KFX88893.1 - 0.014 15.6 0.6 0.036 14.3 0.6 1.6 1 0 0 1 1 1 0 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.6 KFX88893.1 - 0.077 13.2 0.4 0.17 12.0 0.4 1.5 1 0 0 1 1 1 0 PHD-zinc-finger like domain PHD_2 PF13831.6 KFX88893.1 - 0.078 12.5 0.9 0.16 11.5 0.9 1.5 1 0 0 1 1 1 0 PHD-finger RraA-like PF03737.15 KFX88894.1 - 1.6e-19 70.6 6.2 2.1e-19 70.2 6.2 1.2 1 0 0 1 1 1 1 Aldolase/RraA ERCC4 PF02732.15 KFX88895.1 - 2.2e-18 67.0 0.2 3.7e-18 66.2 0.2 1.3 1 0 0 1 1 1 1 ERCC4 domain MCR_D PF02505.14 KFX88895.1 - 0.067 13.0 0.8 0.21 11.4 0.3 1.9 1 1 1 2 2 2 0 Methyl-coenzyme M reductase operon protein D Radical_SAM PF04055.21 KFX88895.1 - 0.16 12.3 0.0 0.45 10.9 0.0 1.6 2 0 0 2 2 2 0 Radical SAM superfamily ERCC4 PF02732.15 KFX88896.1 - 4.2e-08 33.5 0.0 7e-08 32.8 0.0 1.3 1 0 0 1 1 1 1 ERCC4 domain HHH_8 PF14716.6 KFX88896.1 - 0.01 16.1 0.0 0.018 15.4 0.0 1.4 1 0 0 1 1 1 0 Helix-hairpin-helix domain Spo0M PF07070.11 KFX88896.1 - 0.065 12.8 0.0 0.099 12.2 0.0 1.2 1 0 0 1 1 1 0 SpoOM protein PGM_PMM_I PF02878.16 KFX88897.1 - 2.6e-18 66.1 0.1 5.3e-09 35.9 0.0 2.8 1 1 1 2 2 2 2 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_IV PF00408.20 KFX88897.1 - 7.9e-14 51.6 1.4 2e-13 50.3 1.2 1.8 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain PGM_PMM_III PF02880.16 KFX88897.1 - 0.00028 21.1 0.1 0.00096 19.3 0.1 2.1 1 1 1 2 2 2 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_II PF02879.16 KFX88897.1 - 0.0023 18.5 0.3 0.027 15.1 0.3 2.8 1 1 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II Lum_binding PF00677.17 KFX88898.1 - 3.8e-43 145.4 2.3 7.7e-22 77.1 0.4 2.5 2 0 0 2 2 2 2 Lumazine binding domain F-box-like PF12937.7 KFX88898.1 - 0.0047 16.8 0.2 0.012 15.5 0.2 1.7 1 0 0 1 1 1 1 F-box-like PINIT PF14324.6 KFX88901.1 - 1.3e-43 148.9 0.1 2.3e-43 148.0 0.1 1.4 1 0 0 1 1 1 1 PINIT domain zf-MIZ PF02891.20 KFX88901.1 - 1.3e-21 76.1 5.1 2.4e-21 75.2 5.1 1.5 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger zf-Nse PF11789.8 KFX88901.1 - 6.8e-06 25.8 1.3 1.7e-05 24.5 1.3 1.7 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-Sec23_Sec24 PF04810.15 KFX88901.1 - 0.019 15.0 0.0 0.066 13.3 0.0 1.9 1 0 0 1 1 1 0 Sec23/Sec24 zinc finger HU-HIG PF18291.1 KFX88901.1 - 0.092 12.8 0.1 14 5.8 0.0 2.3 2 0 0 2 2 2 0 HU domain fused to wHTH, Ig, or Glycine-rich motif zf-C3HC4_4 PF15227.6 KFX88901.1 - 0.41 10.8 2.5 0.92 9.7 2.5 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Aldo_ket_red PF00248.21 KFX88902.1 - 4.4e-52 177.1 0.0 1.8e-51 175.1 0.0 1.7 1 1 0 1 1 1 1 Aldo/keto reductase family Patatin PF01734.22 KFX88911.1 - 2.6e-07 31.0 0.0 4.6e-07 30.2 0.0 1.4 1 0 0 1 1 1 1 Patatin-like phospholipase DUF2975 PF11188.8 KFX88916.1 - 0.0027 17.6 1.7 0.005 16.7 0.9 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF2975) ECH_1 PF00378.20 KFX88918.1 - 1.1e-14 54.3 0.0 1.3e-14 54.1 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KFX88918.1 - 2e-06 27.5 0.0 4.7e-06 26.3 0.0 1.4 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase Peptidase_S49 PF01343.18 KFX88918.1 - 0.0003 20.8 0.0 0.57 10.1 0.0 2.4 2 0 0 2 2 2 2 Peptidase family S49 Glycos_transf_1 PF00534.20 KFX88919.1 - 2.6e-35 121.5 0.0 8.9e-35 119.7 0.0 1.8 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 KFX88919.1 - 1.3e-15 57.9 0.0 2e-15 57.2 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_1_4 PF13692.6 KFX88919.1 - 1.6e-14 54.5 0.2 5.1e-14 52.8 0.2 1.9 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 KFX88919.1 - 1.7e-07 31.8 0.8 3.9e-07 30.6 0.0 1.9 2 0 0 2 2 2 1 Glycosyl transferase 4-like domain Glyco_trans_1_2 PF13524.6 KFX88919.1 - 5e-05 23.6 0.0 9.1e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 ALG11_N PF15924.5 KFX88919.1 - 0.0027 17.8 0.9 0.33 11.0 0.0 2.5 1 1 1 2 2 2 2 ALG11 mannosyltransferase N-terminus Bul1_N PF04425.12 KFX88927.1 - 0.18 10.5 0.0 0.24 10.1 0.0 1.1 1 0 0 1 1 1 0 Bul1 N terminus zf-C2H2 PF00096.26 KFX88928.1 - 7.4e-10 38.7 4.4 3.9e-06 27.0 0.9 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KFX88928.1 - 3.9e-08 33.4 14.5 1.7e-06 28.2 0.8 2.8 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 KFX88928.1 - 0.0014 19.3 0.9 0.0014 19.3 0.9 3.1 3 0 0 3 3 3 2 C2H2-type zinc finger Zn_ribbon_SprT PF17283.2 KFX88928.1 - 0.0061 16.4 0.7 0.0061 16.4 0.7 2.3 2 0 0 2 2 2 1 SprT-like zinc ribbon domain zf-C2HC_2 PF13913.6 KFX88928.1 - 0.012 15.6 0.6 0.038 13.9 0.6 1.9 1 0 0 1 1 1 0 zinc-finger of a C2HC-type zf-C2H2_6 PF13912.6 KFX88928.1 - 0.035 14.1 0.3 0.035 14.1 0.3 2.2 2 0 0 2 2 2 0 C2H2-type zinc finger zf-H2C2_5 PF13909.6 KFX88928.1 - 0.16 11.7 5.1 0.96 9.3 1.7 2.8 2 1 0 2 2 2 0 C2H2-type zinc-finger domain zf-met2 PF12907.7 KFX88934.1 - 5.7e-15 55.2 4.3 8.2e-15 54.7 4.3 1.3 1 0 0 1 1 1 1 Zinc-binding 4F5 PF04419.14 KFX88934.1 - 0.00015 22.5 9.1 0.00024 21.9 9.1 1.3 1 0 0 1 1 1 1 4F5 protein family Iso_dh PF00180.20 KFX88964.1 - 1.1e-71 241.8 0.0 1.5e-71 241.4 0.0 1.2 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Ino80_Iec3 PF14612.6 KFX88964.1 - 4.5e-70 237.0 0.4 7.6e-70 236.3 0.4 1.4 1 0 0 1 1 1 1 IEC3 subunit of the Ino80 complex, chromatin re-modelling RRM_1 PF00076.22 KFX88965.1 - 4.1e-23 81.0 0.0 3.1e-12 46.2 0.0 3.8 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KFX88965.1 - 7.6e-05 22.8 0.0 0.14 12.3 0.0 3.0 2 0 0 2 2 2 2 RNA recognition motif PAN_3 PF08277.12 KFX88965.1 - 0.39 10.5 0.0 0.39 10.5 0.0 1.9 2 0 0 2 2 2 0 PAN-like domain EOS1 PF12326.8 KFX88965.1 - 0.83 9.6 4.9 6.7 6.6 0.0 2.4 2 0 0 2 2 2 0 N-glycosylation protein zf-3CxxC PF13695.6 KFX88967.1 - 9.2e-14 51.7 0.0 1.7e-13 50.9 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding domain Ndc1_Nup PF09531.10 KFX88967.1 - 0.032 12.9 1.3 0.035 12.8 1.3 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Pneumo_att_G PF05539.11 KFX88967.1 - 3.1 7.3 8.5 3.8 7.0 8.5 1.1 1 0 0 1 1 1 0 Pneumovirinae attachment membrane glycoprotein G CP2 PF04516.15 KFX88970.1 - 2.7e-68 229.7 0.0 3.9e-68 229.2 0.0 1.2 1 0 0 1 1 1 1 CP2 transcription factor TMF_TATA_bd PF12325.8 KFX88976.1 - 6.3e-40 136.0 10.4 6.3e-40 136.0 10.4 6.1 3 2 4 7 7 7 2 TATA element modulatory factor 1 TATA binding TMF_DNA_bd PF12329.8 KFX88976.1 - 5.3e-19 68.0 12.6 5.3e-19 68.0 12.6 7.4 5 3 1 6 6 6 1 TATA element modulatory factor 1 DNA binding ATG16 PF08614.11 KFX88976.1 - 0.013 15.7 3.8 0.013 15.7 3.8 5.9 3 1 4 7 7 7 0 Autophagy protein 16 (ATG16) Holin_BhlA PF10960.8 KFX88976.1 - 0.044 13.7 7.9 0.19 11.7 0.4 3.3 2 0 0 2 2 2 0 BhlA holin family Filament PF00038.21 KFX88976.1 - 0.14 11.7 75.4 0.052 13.1 28.3 4.1 2 1 2 4 4 4 0 Intermediate filament protein WD40_alt PF14077.6 KFX88976.1 - 3.4 7.6 15.4 0.099 12.5 0.9 4.8 5 0 0 5 5 5 0 Alternative WD40 repeat motif Ank_2 PF12796.7 KFX88977.1 - 5.1e-48 161.6 0.2 1.5e-14 54.3 0.0 3.5 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KFX88977.1 - 5.2e-39 132.1 1.4 1.9e-08 34.7 0.0 5.2 1 1 4 5 5 5 5 Ankyrin repeats (many copies) Ank_5 PF13857.6 KFX88977.1 - 3.5e-37 126.0 0.9 9.8e-10 38.5 0.0 5.6 1 1 5 6 6 6 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFX88977.1 - 1.5e-28 95.7 0.0 0.00057 20.1 0.0 6.2 6 0 0 6 6 6 6 Ankyrin repeat Ank PF00023.30 KFX88977.1 - 1.2e-26 91.9 1.0 6.5e-06 26.4 0.0 6.2 6 0 0 6 6 6 6 Ankyrin repeat WD40 PF00400.32 KFX88978.1 - 6.9e-44 147.0 14.2 1.6e-09 38.2 0.1 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFX88978.1 - 1.9e-05 24.8 0.4 10 6.5 0.0 5.1 1 1 5 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KFX88978.1 - 0.018 13.7 1.5 10 4.7 0.0 4.1 2 1 3 5 5 5 0 Nucleoporin Nup120/160 WD40_like PF17005.5 KFX88978.1 - 0.2 11.0 0.0 0.56 9.5 0.0 1.7 2 0 0 2 2 2 0 WD40-like domain AAA PF00004.29 KFX88979.1 - 9.7e-16 58.4 0.0 2.6e-15 57.0 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_10 PF17872.1 KFX88979.1 - 7e-11 42.1 0.0 2e-10 40.7 0.0 1.7 1 0 0 1 1 1 1 AAA lid domain AAA_22 PF13401.6 KFX88979.1 - 1.3e-10 41.7 0.0 1.8e-09 38.0 0.0 2.5 3 0 0 3 3 3 1 AAA domain AAA_16 PF13191.6 KFX88979.1 - 1.7e-10 41.6 0.0 2e-09 38.1 0.0 2.6 2 1 0 2 2 2 1 AAA ATPase domain BAH PF01426.18 KFX88979.1 - 2e-08 34.1 0.0 6.4e-08 32.5 0.0 1.8 2 0 0 2 2 2 1 BAH domain AAA_11 PF13086.6 KFX88979.1 - 0.0038 17.0 0.7 0.014 15.2 0.0 2.2 3 0 0 3 3 3 1 AAA domain AAA_19 PF13245.6 KFX88979.1 - 0.0052 17.1 0.0 0.012 15.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain ATPase_2 PF01637.18 KFX88979.1 - 0.009 16.0 0.1 0.44 10.4 0.0 2.9 2 1 0 2 2 2 1 ATPase domain predominantly from Archaea AAA_18 PF13238.6 KFX88979.1 - 0.015 15.8 0.0 0.046 14.3 0.0 1.9 1 0 0 1 1 1 0 AAA domain DUF2075 PF09848.9 KFX88979.1 - 0.017 14.3 0.0 0.032 13.5 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) RNA_helicase PF00910.22 KFX88979.1 - 0.032 14.6 0.1 0.5 10.8 0.0 2.7 3 0 0 3 3 3 0 RNA helicase AAA_28 PF13521.6 KFX88979.1 - 0.034 14.4 0.0 0.08 13.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_32 PF13654.6 KFX88979.1 - 0.034 12.9 0.0 0.08 11.7 0.0 1.5 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 KFX88979.1 - 0.037 13.9 0.0 0.12 12.3 0.0 1.9 1 1 0 1 1 1 0 NACHT domain PIF1 PF05970.14 KFX88979.1 - 0.13 11.4 0.0 0.23 10.6 0.0 1.3 1 0 0 1 1 1 0 PIF1-like helicase Prefoldin PF02996.17 KFX88981.1 - 4e-26 91.3 0.1 5.5e-26 90.8 0.1 1.1 1 0 0 1 1 1 1 Prefoldin subunit Prefoldin_2 PF01920.20 KFX88981.1 - 0.0029 17.5 2.6 0.42 10.6 0.4 2.1 2 0 0 2 2 2 2 Prefoldin subunit Med30 PF11315.8 KFX88981.1 - 0.0096 16.1 0.0 0.88 9.8 0.0 2.1 2 0 0 2 2 2 1 Mediator complex subunit 30 GIT_CC PF16559.5 KFX88981.1 - 0.011 15.6 0.4 0.023 14.6 0.4 1.5 1 0 0 1 1 1 0 GIT coiled-coil Rho guanine nucleotide exchange factor UvsW PF11637.8 KFX88981.1 - 0.015 15.4 0.0 0.029 14.4 0.0 1.6 1 0 0 1 1 1 0 ATP-dependant DNA helicase UvsW DUF1664 PF07889.12 KFX88981.1 - 0.018 15.1 1.2 0.54 10.3 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Baculo_PEP_C PF04513.12 KFX88981.1 - 0.05 13.6 0.6 0.34 10.9 0.1 2.0 1 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF4854 PF16146.5 KFX88981.1 - 0.086 13.2 0.4 0.45 10.9 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4854) Sec2p PF06428.11 KFX88981.1 - 0.092 12.7 2.5 5 7.2 0.3 2.2 2 0 0 2 2 2 0 GDP/GTP exchange factor Sec2p Fib_alpha PF08702.10 KFX88981.1 - 0.13 12.4 1.0 14 5.9 0.0 2.0 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family tRNA-synt_2b PF00587.25 KFX88982.1 - 1.3e-29 103.5 0.0 1.3e-25 90.4 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 KFX88982.1 - 1.9e-10 40.7 0.0 3.5e-10 39.9 0.0 1.4 1 0 0 1 1 1 1 Anticodon binding domain CBF PF03914.17 KFX88983.1 - 1.2e-54 184.9 0.1 4.2e-54 183.1 0.1 2.0 1 0 0 1 1 1 1 CBF/Mak21 family Cnd1 PF12717.7 KFX88983.1 - 0.21 11.6 0.5 2.3 8.2 0.1 2.3 2 0 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1 4HBT PF03061.22 KFX88984.1 - 1.8e-10 41.0 0.0 4e-10 39.9 0.0 1.6 1 0 0 1 1 1 1 Thioesterase superfamily DUF4936 PF16290.5 KFX88984.1 - 0.013 16.2 0.1 1.3 9.7 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4936) Cupin_2 PF07883.11 KFX88986.1 - 3.5e-15 55.5 0.6 6.1e-15 54.7 0.2 1.6 2 0 0 2 2 2 1 Cupin domain MannoseP_isomer PF01050.18 KFX88986.1 - 0.054 13.4 0.0 0.08 12.8 0.0 1.2 1 0 0 1 1 1 0 Mannose-6-phosphate isomerase DMSP_lyase PF16867.5 KFX88986.1 - 0.094 12.3 0.1 0.16 11.6 0.1 1.3 1 0 0 1 1 1 0 Dimethlysulfonioproprionate lyase EutQ PF06249.12 KFX88986.1 - 0.14 11.9 0.0 0.23 11.2 0.0 1.2 1 0 0 1 1 1 0 Ethanolamine utilisation protein EutQ RRM_1 PF00076.22 KFX88990.1 - 4.6e-19 68.0 1.3 5.8e-19 67.7 0.3 1.6 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KFX88990.1 - 1.1e-05 25.0 0.0 1.3e-05 24.8 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PHM7_cyt PF14703.6 KFX88990.1 - 0.029 14.6 0.1 0.068 13.4 0.1 1.7 1 1 0 1 1 1 0 Cytosolic domain of 10TM putative phosphate transporter RRM_occluded PF16842.5 KFX88990.1 - 0.03 14.2 0.0 0.042 13.7 0.0 1.2 1 0 0 1 1 1 0 Occluded RNA-recognition motif Frankia_peptide PF14407.6 KFX88990.1 - 0.047 13.7 0.1 1.7 8.7 0.0 2.7 2 1 1 3 3 3 0 Ribosomally synthesized peptide prototyped by Frankia Franean1_4349. DUF4523 PF15023.6 KFX88990.1 - 0.12 12.2 0.0 0.2 11.5 0.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF4523) PRIMA1 PF16101.5 KFX88999.1 - 1.8 8.6 7.0 1.9 8.5 7.0 1.2 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 Glyco_hydro_43 PF04616.14 KFX89000.1 - 1.1e-32 113.5 2.9 1.4e-32 113.2 2.9 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 Mito_carr PF00153.27 KFX89003.1 - 4.5e-46 154.7 9.8 1.9e-17 63.0 0.3 3.4 3 0 0 3 3 3 3 Mitochondrial carrier protein CBS PF00571.28 KFX89004.1 - 3.4e-05 24.2 0.1 0.049 14.1 0.0 3.1 1 1 1 2 2 2 2 CBS domain DUF3602 PF12223.8 KFX89005.1 - 2.6e-23 82.4 13.0 3.1e-22 79.0 5.3 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF3602) CENP-B_dimeris PF09026.10 KFX89006.1 - 0.7 10.3 10.1 1.3 9.5 10.1 1.4 1 0 0 1 1 1 0 Centromere protein B dimerisation domain HeLo PF14479.6 KFX89008.1 - 7.1e-07 29.3 0.0 0.026 14.4 0.0 2.3 2 0 0 2 2 2 2 Prion-inhibition and propagation Kdo PF06293.14 KFX89008.1 - 0.0091 15.4 0.1 0.021 14.2 0.0 1.5 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_Tyr PF07714.17 KFX89008.1 - 0.078 12.3 0.0 0.12 11.6 0.0 1.2 1 0 0 1 1 1 0 Protein tyrosine kinase zf-C4H2 PF10146.9 KFX89012.1 - 0.0032 17.8 1.8 0.0055 17.0 1.8 1.3 1 0 0 1 1 1 1 Zinc finger-containing protein Chorismate_bind PF00425.18 KFX89013.1 - 2.8e-77 259.8 0.0 3.9e-77 259.3 0.0 1.2 1 0 0 1 1 1 1 chorismate binding enzyme Anth_synt_I_N PF04715.13 KFX89013.1 - 0.07 13.3 0.5 3.4 7.9 0.6 2.3 1 1 0 2 2 2 0 Anthranilate synthase component I, N terminal region POR PF01558.18 KFX89013.1 - 0.071 13.2 0.0 0.14 12.2 0.0 1.4 1 0 0 1 1 1 0 Pyruvate ferredoxin/flavodoxin oxidoreductase Mycoplasma_p37 PF06646.11 KFX89013.1 - 0.18 11.0 0.0 0.38 9.9 0.0 1.5 2 0 0 2 2 2 0 High affinity transport system protein p37 LSM PF01423.22 KFX89014.1 - 2.8e-15 55.7 0.0 4.7e-15 55.0 0.0 1.4 1 0 0 1 1 1 1 LSM domain ARID PF01388.21 KFX89026.1 - 7.1e-20 71.5 0.1 1.7e-19 70.3 0.1 1.7 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain Apolipoprotein PF01442.18 KFX89027.1 - 0.0042 17.0 2.8 0.0042 17.0 2.8 1.7 2 0 0 2 2 2 1 Apolipoprotein A1/A4/E domain Prominin PF05478.11 KFX89027.1 - 0.0091 14.0 0.3 0.0091 14.0 0.3 1.4 2 0 0 2 2 2 1 Prominin TPR_9 PF13371.6 KFX89027.1 - 0.13 12.4 0.1 0.35 11.1 0.1 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat ApoLp-III PF07464.11 KFX89027.1 - 7.7 6.6 9.6 2.3 8.3 2.3 2.9 3 0 0 3 3 3 0 Apolipophorin-III precursor (apoLp-III) F-actin_cap_A PF01267.17 KFX89028.1 - 7e-96 320.7 0.0 9.2e-96 320.3 0.0 1.2 1 0 0 1 1 1 1 F-actin capping protein alpha subunit Cyt-b5 PF00173.28 KFX89028.1 - 2.5e-22 78.8 0.3 8.2e-22 77.1 0.1 1.9 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain VHS PF00790.19 KFX89029.1 - 1.2e-32 112.7 1.6 2.1e-32 111.9 1.6 1.4 1 0 0 1 1 1 1 VHS domain SH3_1 PF00018.28 KFX89029.1 - 3.8e-16 58.4 0.0 7.8e-16 57.4 0.0 1.6 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KFX89029.1 - 1.8e-14 53.3 0.0 3.5e-14 52.4 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 KFX89029.1 - 1e-13 50.8 0.0 1.9e-13 49.9 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain GAT PF03127.14 KFX89029.1 - 6.8e-10 39.1 1.5 2.1e-09 37.5 0.5 2.3 2 0 0 2 2 2 1 GAT domain UIM PF02809.20 KFX89029.1 - 0.062 13.2 2.9 0.14 12.1 2.9 1.6 1 0 0 1 1 1 0 Ubiquitin interaction motif DUF3361 PF11841.8 KFX89029.1 - 0.076 13.0 0.1 0.16 11.9 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3361) PEP-utilisers_N PF05524.13 KFX89029.1 - 4.5 7.5 6.0 0.91 9.7 0.4 2.4 2 0 0 2 2 2 0 PEP-utilising enzyme, N-terminal LRR_6 PF13516.6 KFX89030.1 - 2.1e-11 42.9 13.1 0.00019 21.2 0.0 8.1 9 0 0 9 9 9 2 Leucine Rich repeat F-box-like PF12937.7 KFX89030.1 - 6.1e-09 35.6 2.0 1.4e-08 34.5 0.8 2.3 3 0 0 3 3 3 1 F-box-like F-box PF00646.33 KFX89030.1 - 3e-06 27.0 0.8 1.3e-05 24.9 0.8 2.2 1 0 0 1 1 1 1 F-box domain LRR_4 PF12799.7 KFX89030.1 - 1.3e-05 25.4 11.0 0.18 12.3 0.0 6.6 3 2 3 7 7 7 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 KFX89030.1 - 0.089 13.4 15.8 5.2 8.0 0.2 7.6 9 1 0 9 9 9 0 Leucine Rich Repeat Ribosomal_L3 PF00297.22 KFX89031.1 - 1.1e-185 616.9 11.9 1.3e-185 616.7 11.9 1.0 1 0 0 1 1 1 1 Ribosomal protein L3 SCNM1_acidic PF15805.5 KFX89032.1 - 0.087 12.6 0.7 0.17 11.6 0.7 1.4 1 0 0 1 1 1 0 Acidic C-terminal region of sodium channel modifier 1 SCNM1 IMS PF00817.20 KFX89033.1 - 1.2e-39 135.7 0.0 1.8e-39 135.1 0.0 1.3 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.8 KFX89033.1 - 5.5e-17 62.6 0.3 3.9e-15 56.6 0.1 2.3 2 0 0 2 2 2 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.8 KFX89033.1 - 0.0067 16.7 0.0 0.022 15.0 0.0 2.0 1 0 0 1 1 1 1 IMS family HHH motif G_glu_transpept PF01019.21 KFX89034.1 - 8.2e-162 539.5 0.1 9.4e-162 539.3 0.1 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase PI-PLC-Y PF00387.19 KFX89039.1 - 3.5e-43 146.6 0.0 5.2e-43 146.0 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain C2 PF00168.30 KFX89039.1 - 4.8e-08 33.2 0.1 2.5e-06 27.7 0.1 2.8 1 1 1 2 2 2 1 C2 domain DUF3747 PF12565.8 KFX89045.1 - 0.061 12.7 0.4 7.5 5.9 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3747) UCH PF00443.29 KFX89047.1 - 2.2e-68 230.6 0.0 3e-68 230.1 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KFX89047.1 - 3.3e-10 40.1 0.0 0.0011 18.6 0.0 3.2 2 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase DUSP PF06337.12 KFX89047.1 - 3e-08 34.1 0.0 7.3e-08 32.9 0.0 1.7 1 0 0 1 1 1 1 DUSP domain Zn_ribbon_SprT PF17283.2 KFX89047.1 - 2 8.4 3.9 0.92 9.5 0.7 1.9 2 0 0 2 2 2 0 SprT-like zinc ribbon domain MPP6 PF10175.9 KFX89051.1 - 3.7e-08 33.9 17.5 2e-07 31.5 12.7 3.0 1 1 1 2 2 2 1 M-phase phosphoprotein 6 zf-CCHC PF00098.23 KFX89051.1 - 8.3e-08 32.0 1.7 1.5e-07 31.1 1.7 1.5 1 0 0 1 1 1 1 Zinc knuckle Nop53 PF07767.11 KFX89051.1 - 0.00044 19.8 7.5 0.00044 19.8 7.5 1.8 2 0 0 2 2 2 1 Nop53 (60S ribosomal biogenesis) CDC45 PF02724.14 KFX89051.1 - 0.027 12.8 7.8 0.041 12.2 7.8 1.2 1 0 0 1 1 1 0 CDC45-like protein zf-CCHC_3 PF13917.6 KFX89051.1 - 0.088 12.8 0.2 0.16 12.0 0.2 1.5 1 0 0 1 1 1 0 Zinc knuckle YL1 PF05764.13 KFX89051.1 - 0.098 12.8 17.1 0.025 14.7 11.9 2.0 2 0 0 2 2 2 0 YL1 nuclear protein Cwf_Cwc_15 PF04889.12 KFX89051.1 - 0.24 11.1 22.0 0.54 10.0 22.1 1.6 1 1 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein zf-CHCC PF10276.9 KFX89052.1 - 8.5e-17 60.9 1.7 1.7e-16 59.9 1.7 1.5 1 0 0 1 1 1 1 Zinc-finger domain Glyco_transf_21 PF13506.6 KFX89053.1 - 0.0003 20.3 0.0 0.0014 18.1 0.0 2.1 1 1 0 1 1 1 1 Glycosyl transferase family 21 Lactamase_B_2 PF12706.7 KFX89055.1 - 6.5e-30 104.2 0.1 2.2e-27 95.9 0.1 3.0 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 KFX89055.1 - 4.6e-10 39.6 0.0 9.3e-10 38.6 0.0 1.7 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 KFX89055.1 - 0.00039 20.5 0.4 0.0011 19.0 0.1 1.8 2 0 0 2 2 2 1 Metallo-beta-lactamase superfamily Prok-JAB PF14464.6 KFX89055.1 - 0.13 12.1 0.1 0.23 11.2 0.1 1.4 1 0 0 1 1 1 0 Prokaryotic homologs of the JAB domain Abhydrolase_3 PF07859.13 KFX89056.1 - 7.5e-13 48.8 0.0 1e-12 48.4 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold APH PF01636.23 KFX89060.1 - 6.5e-17 62.3 0.1 1.3e-16 61.3 0.1 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KFX89060.1 - 0.00049 19.7 0.0 0.0044 16.6 0.0 2.0 2 0 0 2 2 2 1 Choline/ethanolamine kinase EcKinase PF02958.20 KFX89060.1 - 0.0019 17.6 0.0 0.0033 16.8 0.0 1.3 1 0 0 1 1 1 1 Ecdysteroid kinase RIO1 PF01163.22 KFX89060.1 - 0.048 13.3 0.0 0.099 12.2 0.0 1.5 1 1 0 1 1 1 0 RIO1 family zf-ribbon_3 PF13248.6 KFX89061.1 - 0.036 13.5 0.1 0.079 12.4 0.1 1.6 1 0 0 1 1 1 0 zinc-ribbon domain LSR PF05624.14 KFX89063.1 - 2.5 8.2 6.4 0.15 12.1 1.1 1.6 2 0 0 2 2 2 0 Lipolysis stimulated receptor (LSR) GCP_N_terminal PF17681.1 KFX89064.1 - 8e-29 101.2 0.0 1.2e-28 100.7 0.0 1.2 1 0 0 1 1 1 1 Gamma tubulin complex component N-terminal GCP_C_terminal PF04130.13 KFX89064.1 - 2.9e-24 86.1 0.0 9.3e-24 84.4 0.0 1.7 2 0 0 2 2 2 1 Gamma tubulin complex component C-terminal GCP5-Mod21 PF14609.6 KFX89064.1 - 0.00012 20.5 0.0 0.00033 19.2 0.0 1.7 1 1 0 1 1 1 1 gamma-Tubulin ring complex non-core subunit mod21 AF-4 PF05110.13 KFX89064.1 - 0.72 7.9 4.5 1.1 7.3 4.5 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein Glyco_transf_15 PF01793.16 KFX89065.1 - 4.3e-111 371.3 6.7 6.2e-111 370.7 6.7 1.2 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase Aminotran_1_2 PF00155.21 KFX89065.1 - 9.3e-14 51.4 0.0 3.6e-13 49.4 0.0 1.8 1 1 0 1 1 1 1 Aminotransferase class I and II Tannase PF07519.11 KFX89065.1 - 0.0059 15.6 0.0 0.012 14.6 0.0 1.4 1 0 0 1 1 1 1 Tannase and feruloyl esterase MTHFR PF02219.17 KFX89066.1 - 5.5e-103 344.2 0.0 8e-103 343.7 0.0 1.1 1 0 0 1 1 1 1 Methylenetetrahydrofolate reductase Hira PF07569.11 KFX89076.1 - 5.1e-72 242.2 0.0 2.7e-71 239.8 0.0 2.2 3 0 0 3 3 3 1 TUP1-like enhancer of split WD40 PF00400.32 KFX89076.1 - 1.7e-30 104.6 25.8 1.7e-05 25.5 0.3 9.5 9 1 0 9 9 9 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFX89076.1 - 2.4e-16 59.8 0.2 0.0052 17.1 0.0 5.8 2 1 3 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain HIRA_B PF09453.10 KFX89076.1 - 8.1e-10 38.3 0.8 8.1e-10 38.3 0.8 1.9 2 0 0 2 2 2 1 HIRA B motif PD40 PF07676.12 KFX89076.1 - 7.2e-08 32.2 0.4 0.22 11.5 0.0 5.1 5 0 0 5 5 5 3 WD40-like Beta Propeller Repeat Ge1_WD40 PF16529.5 KFX89076.1 - 2.1e-05 23.6 1.1 0.22 10.4 0.0 4.5 4 1 2 6 6 6 2 WD40 region of Ge1, enhancer of mRNA-decapping protein IKI3 PF04762.12 KFX89076.1 - 0.0025 15.9 0.1 0.045 11.8 0.0 2.4 3 0 0 3 3 3 1 IKI3 family PQQ_3 PF13570.6 KFX89076.1 - 9.8 6.8 7.6 45 4.7 0.0 4.4 4 0 0 4 4 4 0 PQQ-like domain CoA_binding PF02629.19 KFX89078.1 - 2.5e-20 73.0 0.0 1.5e-19 70.4 0.0 2.0 2 0 0 2 2 2 1 CoA binding domain ATP_sub_h PF10775.9 KFX89078.1 - 0.075 13.0 0.7 1.3 9.1 0.0 2.2 2 0 0 2 2 2 0 ATP synthase complex subunit h CoA_binding_2 PF13380.6 KFX89078.1 - 0.11 12.9 0.0 0.18 12.3 0.0 1.2 1 0 0 1 1 1 0 CoA binding domain CEP1-DNA_bind PF09287.10 KFX89078.1 - 0.25 11.0 0.0 0.55 9.8 0.0 1.5 1 0 0 1 1 1 0 CEP-1, DNA binding Citrate_bind PF16114.5 KFX89079.1 - 7.3e-88 292.7 0.0 1e-87 292.2 0.0 1.2 1 0 0 1 1 1 1 ATP citrate lyase citrate-binding ATP-grasp_2 PF08442.10 KFX89079.1 - 1e-06 28.5 0.0 1.7e-06 27.7 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain Reovirus_M2 PF05993.12 KFX89079.1 - 0.058 11.5 0.0 0.079 11.1 0.0 1.1 1 0 0 1 1 1 0 Reovirus major virion structural protein Mu-1/Mu-1C (M2) Glyco_hydro_72 PF03198.14 KFX89080.1 - 3e-113 378.2 0.1 3.7e-113 377.9 0.1 1.0 1 0 0 1 1 1 1 Glucanosyltransferase Glyco_hydro_2_C PF02836.17 KFX89080.1 - 8.5e-05 21.8 0.0 0.00015 21.0 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Cellulase PF00150.18 KFX89080.1 - 0.087 12.2 0.3 3.7 6.9 0.3 2.1 1 1 0 1 1 1 0 Cellulase (glycosyl hydrolase family 5) Piwi PF02171.17 KFX89093.1 - 1.1e-44 152.9 0.0 1.7e-44 152.3 0.0 1.2 1 0 0 1 1 1 1 Piwi domain ArgoL2 PF16488.5 KFX89093.1 - 6e-12 45.7 0.0 1.6e-11 44.3 0.0 1.8 1 0 0 1 1 1 1 Argonaute linker 2 domain ArgoL1 PF08699.10 KFX89093.1 - 5.6e-10 38.7 0.0 2.2e-09 36.8 0.0 2.1 1 0 0 1 1 1 1 Argonaute linker 1 domain ArgoMid PF16487.5 KFX89093.1 - 7.2e-10 39.0 0.0 2.3e-09 37.4 0.0 1.8 2 0 0 2 2 2 1 Mid domain of argonaute ArgoN PF16486.5 KFX89093.1 - 4.1e-07 30.7 0.0 9.6e-07 29.5 0.0 1.7 1 0 0 1 1 1 1 N-terminal domain of argonaute PAZ PF02170.22 KFX89093.1 - 5.1e-05 23.1 0.0 9.2e-05 22.3 0.0 1.4 1 0 0 1 1 1 1 PAZ domain Arm-DNA-bind_2 PF12167.8 KFX89093.1 - 0.056 13.4 0.0 0.15 12.0 0.0 1.7 1 0 0 1 1 1 0 Arm DNA-binding domain ACBP PF00887.19 KFX89094.1 - 1.1e-15 57.5 0.8 1.6e-15 57.0 0.8 1.2 1 0 0 1 1 1 1 Acyl CoA binding protein Tyr-DNA_phospho PF06087.12 KFX89095.1 - 4.5e-148 493.7 0.0 5.2e-148 493.4 0.0 1.0 1 0 0 1 1 1 1 Tyrosyl-DNA phosphodiesterase PLDc_2 PF13091.6 KFX89095.1 - 0.11 12.4 0.0 1.6 8.6 0.0 2.2 2 0 0 2 2 2 0 PLD-like domain PLDc PF00614.22 KFX89095.1 - 0.13 12.5 0.1 8.5 6.7 0.4 2.7 2 0 0 2 2 2 0 Phospholipase D Active site motif Atg8 PF02991.16 KFX89099.1 - 5.7e-51 171.0 0.2 6.7e-51 170.8 0.2 1.0 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like APG12 PF04110.13 KFX89099.1 - 4.4e-06 27.0 0.0 5.4e-06 26.7 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 Coprogen_oxidas PF01218.18 KFX89100.1 - 3.8e-146 485.4 0.2 4.6e-146 485.2 0.2 1.0 1 0 0 1 1 1 1 Coproporphyrinogen III oxidase adh_short PF00106.25 KFX89108.1 - 1e-36 126.2 0.0 1.7e-36 125.5 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KFX89108.1 - 1.5e-20 73.8 0.0 2.6e-20 73.0 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.6 KFX89108.1 - 0.00015 21.7 0.0 0.00029 20.8 0.0 1.5 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KFX89108.1 - 0.0049 16.4 0.0 0.0087 15.5 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.10 KFX89108.1 - 0.0086 16.0 0.0 0.019 14.9 0.0 1.5 1 0 0 1 1 1 1 KR domain NAD_binding_2 PF03446.15 KFX89108.1 - 0.037 14.2 0.0 0.2 11.9 0.0 2.1 2 0 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase 4HBT PF03061.22 KFX89108.1 - 0.07 13.5 0.2 0.35 11.3 0.1 2.1 2 0 0 2 2 2 0 Thioesterase superfamily DUF3520 PF12034.8 KFX89108.1 - 0.36 10.9 1.2 4.5 7.4 0.4 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3520) Peptidase_S8 PF00082.22 KFX89110.1 - 2.1e-31 109.3 25.2 7.7e-18 64.8 8.4 2.4 1 1 1 2 2 2 2 Subtilase family Inhibitor_I9 PF05922.16 KFX89110.1 - 1.1e-09 38.8 0.1 2e-09 38.0 0.1 1.5 1 0 0 1 1 1 1 Peptidase inhibitor I9 DUF515 PF04415.12 KFX89110.1 - 0.35 9.2 0.8 0.49 8.7 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF515) Pkinase PF00069.25 KFX89117.1 - 6.1e-63 212.7 0.0 7.3e-63 212.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFX89117.1 - 6.1e-36 124.0 0.0 1.1e-35 123.2 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KFX89117.1 - 5.9e-07 29.1 0.0 9.3e-07 28.4 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 KFX89117.1 - 0.00072 18.4 0.0 0.001 18.0 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Seadorna_VP7 PF07387.11 KFX89117.1 - 0.1 11.6 0.1 0.15 11.1 0.1 1.1 1 0 0 1 1 1 0 Seadornavirus VP7 Abhydrolase_6 PF12697.7 KFX89118.1 - 1e-13 52.4 0.0 1.3e-13 52.0 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KFX89118.1 - 2.5e-05 23.7 0.0 4e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KFX89118.1 - 0.017 14.7 0.0 0.023 14.3 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold Glyoxalase PF00903.25 KFX89121.1 - 1.9e-22 79.8 0.2 6.1e-15 55.5 0.0 2.2 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 KFX89121.1 - 2.6e-12 47.0 0.0 0.0001 22.5 0.0 2.4 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_5 PF14696.6 KFX89121.1 - 4.6e-07 30.1 0.1 1.2e-05 25.5 0.1 2.7 2 1 0 2 2 2 1 Hydroxyphenylpyruvate dioxygenase, HPPD, N-terminal Glyoxalase_3 PF13468.6 KFX89121.1 - 2.7e-06 27.6 0.1 0.11 12.7 0.2 3.4 2 1 0 2 2 2 2 Glyoxalase-like domain DUF4844 PF16133.5 KFX89121.1 - 0.0096 16.5 0.1 0.052 14.1 0.0 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF4844) Glyoxalase_6 PF18029.1 KFX89121.1 - 0.034 14.9 0.0 1.3 9.9 0.0 2.4 2 0 0 2 2 2 0 Glyoxalase-like domain Cadherin_5 PF17892.1 KFX89122.1 - 0.19 11.7 1.5 3.8 7.6 0.1 2.8 3 1 0 3 3 3 0 Cadherin-like domain polyprenyl_synt PF00348.17 KFX89132.1 - 2.8e-45 154.4 0.0 5.9e-45 153.3 0.0 1.5 1 0 0 1 1 1 1 Polyprenyl synthetase Terpene_synth_C PF03936.16 KFX89132.1 - 1.5e-06 27.7 0.0 0.00091 18.7 0.0 2.6 2 1 0 2 2 2 2 Terpene synthase family, metal binding domain ABC_tran PF00005.27 KFX89133.1 - 2.4e-28 99.3 0.1 4e-28 98.6 0.1 1.4 1 0 0 1 1 1 1 ABC transporter RsgA_GTPase PF03193.16 KFX89133.1 - 5.7e-05 23.1 1.3 9.4e-05 22.4 0.5 1.7 2 0 0 2 2 2 1 RsgA GTPase AAA_21 PF13304.6 KFX89133.1 - 6.2e-05 23.0 1.2 0.048 13.5 0.0 2.3 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_18 PF13238.6 KFX89133.1 - 0.0018 18.8 0.0 0.0028 18.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain MeaB PF03308.16 KFX89133.1 - 0.0051 15.8 0.1 0.0086 15.1 0.1 1.3 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_29 PF13555.6 KFX89133.1 - 0.0088 15.8 0.4 0.023 14.4 0.4 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain Rad17 PF03215.15 KFX89133.1 - 0.011 15.7 0.0 0.019 14.9 0.0 1.3 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_16 PF13191.6 KFX89133.1 - 0.017 15.5 0.0 0.03 14.7 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.6 KFX89133.1 - 0.027 14.7 0.1 0.06 13.6 0.1 1.7 1 1 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 KFX89133.1 - 0.028 14.5 0.3 0.069 13.2 0.3 1.7 1 0 0 1 1 1 0 50S ribosome-binding GTPase SMC_N PF02463.19 KFX89133.1 - 0.1 12.0 1.4 2.8 7.3 0.3 2.2 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain RNA_helicase PF00910.22 KFX89133.1 - 0.17 12.3 0.0 0.36 11.2 0.0 1.5 1 0 0 1 1 1 0 RNA helicase T2SSE PF00437.20 KFX89133.1 - 0.18 10.8 0.2 0.28 10.2 0.2 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein Cytidylate_kin PF02224.18 KFX89133.1 - 0.18 11.5 0.3 0.28 10.9 0.3 1.2 1 0 0 1 1 1 0 Cytidylate kinase GPI-anchored PF10342.9 KFX89141.1 - 2.1e-11 44.4 0.1 1.2e-10 42.0 0.0 2.3 2 0 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Peptidase_C14 PF00656.22 KFX89142.1 - 3.1e-48 164.9 0.0 4.2e-48 164.5 0.0 1.2 1 0 0 1 1 1 1 Caspase domain Raptor_N PF14538.6 KFX89142.1 - 0.029 14.3 0.3 0.36 10.8 0.0 2.5 3 0 0 3 3 3 0 Raptor N-terminal CASPase like domain Epimerase PF01370.21 KFX89150.1 - 1.6e-11 44.2 0.0 4.6e-08 32.8 0.1 2.1 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KFX89150.1 - 3.3e-06 26.7 0.1 1e-05 25.2 0.1 1.7 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 KFX89150.1 - 4.3e-06 25.9 0.1 7.6e-06 25.1 0.1 1.4 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NmrA PF05368.13 KFX89150.1 - 0.00039 20.0 0.3 0.00061 19.4 0.3 1.3 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KFX89150.1 - 0.0013 18.6 0.1 0.0021 18.0 0.1 1.3 1 0 0 1 1 1 1 NAD(P)H-binding RmlD_sub_bind PF04321.17 KFX89150.1 - 0.0025 16.9 0.2 0.2 10.7 0.2 2.3 2 1 0 2 2 2 1 RmlD substrate binding domain TrkA_N PF02254.18 KFX89150.1 - 0.0031 17.8 0.3 0.0065 16.7 0.3 1.5 1 0 0 1 1 1 1 TrkA-N domain KR PF08659.10 KFX89150.1 - 0.005 16.8 0.4 0.0086 16.0 0.4 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_4 PF07993.12 KFX89150.1 - 0.023 13.9 0.4 0.26 10.4 0.4 2.2 1 1 0 1 1 1 0 Male sterility protein Polysacc_synt_2 PF02719.15 KFX89150.1 - 0.041 13.0 0.2 0.065 12.4 0.2 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein ChaC PF04752.12 KFX89151.1 - 6.6e-57 192.4 0.0 7.7e-57 192.2 0.0 1.0 1 0 0 1 1 1 1 ChaC-like protein NAD_binding_8 PF13450.6 KFX89155.1 - 8.7e-16 57.9 0.0 3.9e-15 55.8 0.0 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.24 KFX89155.1 - 2.1e-09 37.2 0.0 6.8e-09 35.5 0.0 1.8 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase DAO PF01266.24 KFX89155.1 - 5.2e-08 32.9 0.0 6.7e-05 22.6 0.0 2.6 3 0 0 3 3 3 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KFX89155.1 - 3.8e-06 26.3 0.0 9e-05 21.8 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KFX89155.1 - 1.5e-05 24.3 0.1 0.00063 18.9 0.1 2.1 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.14 KFX89155.1 - 0.0019 17.0 0.1 0.52 9.0 0.1 2.1 2 0 0 2 2 2 2 HI0933-like protein NAD_binding_9 PF13454.6 KFX89155.1 - 0.0027 17.7 0.1 0.058 13.4 0.0 2.8 3 1 1 4 4 4 1 FAD-NAD(P)-binding Pyr_redox PF00070.27 KFX89155.1 - 0.0064 17.0 0.3 3.7 8.2 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 KFX89155.1 - 0.046 12.6 0.0 0.071 11.9 0.0 1.3 1 0 0 1 1 1 0 Tryptophan halogenase GIDA PF01134.22 KFX89155.1 - 0.15 11.1 0.2 0.25 10.4 0.2 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A Glyoxalase PF00903.25 KFX89157.1 - 0.00051 20.2 0.3 0.0014 18.8 0.3 1.7 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Aldose_epim PF01263.20 KFX89158.1 - 1e-50 172.8 0.9 1.2e-50 172.6 0.9 1.0 1 0 0 1 1 1 1 Aldose 1-epimerase RVT_2 PF07727.14 KFX89162.1 - 1.4e-62 211.5 0.0 2.5e-62 210.7 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Retrotran_gag_2 PF14223.6 KFX89162.1 - 1.9e-15 56.7 0.1 3.8e-15 55.8 0.1 1.4 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type rve PF00665.26 KFX89162.1 - 8e-14 51.9 0.0 2.6e-13 50.2 0.0 2.0 1 0 0 1 1 1 1 Integrase core domain gag_pre-integrs PF13976.6 KFX89162.1 - 1.8e-09 37.3 0.1 2.1e-08 33.9 0.0 2.9 2 0 0 2 2 2 1 GAG-pre-integrase domain Retrotran_gag_3 PF14244.6 KFX89162.1 - 0.005 16.6 0.1 0.037 13.8 0.0 2.3 2 0 0 2 2 2 1 gag-polypeptide of LTR copia-type Zn_clus PF00172.18 KFX89162.1 - 0.024 14.7 85.5 0.029 14.5 10.0 6.1 4 2 0 5 5 5 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Exo70 PF03081.15 KFX89169.1 - 6.6e-84 282.1 0.0 3.6e-83 279.7 0.0 2.0 2 1 1 3 3 3 1 Exo70 exocyst complex subunit Sec34 PF04136.15 KFX89169.1 - 0.44 10.4 3.9 0.95 9.3 0.1 2.9 3 0 0 3 3 3 0 Sec34-like family DUF2203 PF09969.9 KFX89169.1 - 1 10.1 3.8 3.2 8.5 0.1 3.3 4 0 0 4 4 4 0 Uncharacterized conserved protein (DUF2203) zf-CCCH PF00642.24 KFX89173.1 - 1.1e-12 47.5 1.4 4.3e-06 26.5 0.6 2.4 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 KFX89173.1 - 5.8e-09 35.5 1.7 0.0031 17.3 0.8 2.3 2 0 0 2 2 2 2 CCCH-type zinc finger zf_CCCH_4 PF18345.1 KFX89173.1 - 2.1e-08 34.0 5.3 0.00011 22.1 0.8 2.4 2 0 0 2 2 2 2 Zinc finger domain Torus PF16131.5 KFX89173.1 - 1.8e-05 25.4 1.6 0.02 15.6 0.1 2.7 1 1 1 2 2 2 2 Torus domain zf-CCCH_2 PF14608.6 KFX89173.1 - 0.0043 17.5 6.6 0.12 12.9 1.9 2.3 2 0 0 2 2 2 2 RNA-binding, Nab2-type zinc finger TFIIF_beta_N PF17683.1 KFX89174.1 - 2.7e-37 128.5 0.2 8.6e-37 126.8 0.0 1.8 2 0 0 2 2 2 1 TFIIF, beta subunit N-terminus TFIIF_beta PF02270.15 KFX89174.1 - 8e-30 102.8 1.2 1.2e-29 102.2 1.2 1.3 1 0 0 1 1 1 1 TFIIF, beta subunit HTH domain Lum_binding PF00677.17 KFX89174.1 - 0.076 13.0 0.0 0.66 10.0 0.0 2.2 2 0 0 2 2 2 0 Lumazine binding domain CBF PF03914.17 KFX89175.1 - 4.5e-35 121.2 1.8 1.6e-34 119.4 0.1 2.8 4 0 0 4 4 4 1 CBF/Mak21 family Mt_ATP-synt_B PF05405.14 KFX89176.1 - 4.5e-50 169.5 5.1 5.7e-50 169.1 5.1 1.1 1 0 0 1 1 1 1 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) tRNA_anti-codon PF01336.25 KFX89176.1 - 0.0014 18.5 0.1 0.0026 17.7 0.1 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain Adenyl_cycl_N PF12633.7 KFX89176.1 - 0.039 13.9 0.2 0.075 12.9 0.2 1.6 1 1 0 1 1 1 0 Adenylate cyclase NT domain YbjQ_1 PF01906.17 KFX89177.1 - 2e-32 111.9 0.7 2.6e-32 111.5 0.7 1.2 1 0 0 1 1 1 1 Putative heavy-metal-binding Hexapep PF00132.24 KFX89185.1 - 2.1e-06 27.2 11.1 0.016 14.9 0.7 3.7 2 1 1 3 3 3 3 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 KFX89185.1 - 0.03 14.1 6.1 0.41 10.4 0.4 3.9 4 1 0 4 4 4 0 Hexapeptide repeat of succinyl-transferase Fucokinase PF07959.12 KFX89185.1 - 0.056 12.4 0.3 0.063 12.2 0.3 1.1 1 0 0 1 1 1 0 L-fucokinase MFS_1 PF07690.16 KFX89194.1 - 1.1e-09 37.7 12.8 1.3e-09 37.5 12.8 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_3 PF05977.13 KFX89194.1 - 0.082 11.3 0.7 0.12 10.7 0.7 1.3 1 0 0 1 1 1 0 Transmembrane secretion effector Lant_dehydr_C PF14028.6 KFX89194.1 - 0.19 11.3 0.0 0.22 11.0 0.0 1.1 1 0 0 1 1 1 0 Lantibiotic biosynthesis dehydratase C-term Cupin_8 PF13621.6 KFX89195.1 - 1.9e-33 116.3 0.0 3e-33 115.6 0.0 1.2 1 0 0 1 1 1 1 Cupin-like domain LCM PF04072.14 KFX89195.1 - 2.2e-21 76.7 0.0 3.7e-21 75.9 0.0 1.3 1 0 0 1 1 1 1 Leucine carboxyl methyltransferase Kelch_4 PF13418.6 KFX89195.1 - 1.1e-17 63.7 3.0 1.1e-05 25.4 0.0 4.5 4 0 0 4 4 4 3 Galactose oxidase, central domain Kelch_5 PF13854.6 KFX89195.1 - 8e-09 35.3 0.1 0.00011 22.1 0.0 3.9 4 0 0 4 4 4 2 Kelch motif Kelch_6 PF13964.6 KFX89195.1 - 1.1e-05 25.5 7.6 0.0066 16.7 0.0 3.7 4 1 1 5 5 5 2 Kelch motif Cupin_4 PF08007.12 KFX89195.1 - 2.6e-05 23.8 0.0 4.9e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 Cupin superfamily protein Kelch_1 PF01344.25 KFX89195.1 - 0.001 18.6 0.9 0.24 11.0 0.0 3.9 4 0 0 4 4 4 1 Kelch motif Kelch_2 PF07646.15 KFX89195.1 - 0.0016 18.4 4.6 0.27 11.3 0.1 3.9 4 0 0 4 4 4 2 Kelch motif Kelch_3 PF13415.6 KFX89195.1 - 0.047 14.0 4.6 0.14 12.5 0.0 3.5 4 0 0 4 4 4 0 Galactose oxidase, central domain ANAPC4_WD40 PF12894.7 KFX89196.1 - 0.02 15.2 0.0 2.4 8.5 0.0 3.4 3 1 1 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KFX89196.1 - 0.055 14.4 0.2 2.9 8.9 0.0 3.2 3 0 0 3 3 3 0 WD domain, G-beta repeat Citrate_synt PF00285.21 KFX89197.1 - 1.4e-09 37.5 0.0 1.3e-08 34.3 0.0 1.9 1 1 0 1 1 1 1 Citrate synthase, C-terminal domain Mg_trans_NIPA PF05653.14 KFX89201.1 - 3e-71 240.0 27.9 1.6e-47 162.0 11.8 2.1 1 1 1 2 2 2 2 Magnesium transporter NIPA EamA PF00892.20 KFX89201.1 - 2.5e-05 24.5 6.9 2.5e-05 24.5 6.9 3.3 3 0 0 3 3 3 2 EamA-like transporter family DUF5362 PF17319.2 KFX89201.1 - 0.58 10.0 0.0 0.58 10.0 0.0 3.8 4 1 0 4 4 4 0 Family of unknown function (DUF5362) Ndc1_Nup PF09531.10 KFX89201.1 - 0.87 8.2 10.4 1.5 7.5 10.4 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Neurensin PF14927.6 KFX89201.1 - 4 7.1 8.8 0.71 9.6 2.3 2.7 3 0 0 3 3 3 0 Neurensin Asp PF00026.23 KFX89203.1 - 8.6e-39 133.8 5.1 1.7e-37 129.6 5.1 2.0 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KFX89203.1 - 0.00026 21.3 3.4 0.093 13.0 0.4 2.8 2 1 1 3 3 3 2 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 KFX89203.1 - 0.0017 19.0 2.7 0.014 16.0 0.4 3.0 2 2 1 3 3 3 1 Aspartyl protease gag-asp_proteas PF13975.6 KFX89203.1 - 0.045 14.3 0.2 0.35 11.4 0.0 2.2 2 0 0 2 2 2 0 gag-polyprotein putative aspartyl protease HET PF06985.11 KFX89208.1 - 3.5e-22 79.3 0.0 5e-22 78.8 0.0 1.2 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DHHC PF01529.20 KFX89211.1 - 9.2e-27 93.8 1.8 9.2e-27 93.8 1.8 2.2 2 0 0 2 2 2 1 DHHC palmitoyltransferase DUF503 PF04456.12 KFX89212.1 - 0.14 12.1 0.0 0.21 11.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF503) Acetyltransf_1 PF00583.25 KFX89214.1 - 7.3e-11 42.3 0.1 3.8e-10 40.0 0.0 2.1 2 1 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KFX89214.1 - 1.6e-09 37.8 0.0 2.1e-08 34.1 0.0 2.1 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KFX89214.1 - 7.6e-09 35.9 0.1 2.6e-07 31.0 0.0 2.2 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 KFX89214.1 - 0.0005 20.1 0.0 0.00085 19.4 0.0 1.4 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_9 PF13527.7 KFX89214.1 - 0.0029 17.7 0.0 0.4 10.8 0.0 2.3 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain DHquinase_I PF01487.15 KFX89215.1 - 4.3e-19 69.7 0.0 6.7e-19 69.1 0.0 1.3 1 0 0 1 1 1 1 Type I 3-dehydroquinase Shikimate_dh_N PF08501.11 KFX89215.1 - 1.2e-13 51.0 0.1 2.5e-13 50.1 0.1 1.5 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain SDH_C PF18317.1 KFX89215.1 - 4e-10 39.3 0.2 1.1e-09 37.9 0.2 1.8 1 0 0 1 1 1 1 Shikimate 5'-dehydrogenase C-terminal domain Shikimate_DH PF01488.20 KFX89215.1 - 7.1e-08 32.6 0.0 1.3e-07 31.7 0.0 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Sacchrp_dh_NADP PF03435.18 KFX89215.1 - 0.2 11.9 0.0 0.43 10.8 0.0 1.5 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Pal1 PF08316.11 KFX89227.1 - 9.2e-49 165.7 0.5 1.7e-48 164.9 0.5 1.4 1 0 0 1 1 1 1 Pal1 cell morphology protein Big_3_5 PF16640.5 KFX89230.1 - 0.0067 16.6 0.4 0.0082 16.3 0.4 1.1 1 0 0 1 1 1 1 Bacterial Ig-like domain (group 3) RTA1 PF04479.13 KFX89231.1 - 2.7e-44 151.3 1.9 2.7e-44 151.3 1.9 1.4 1 1 1 2 2 2 1 RTA1 like protein PAP2_C PF14360.6 KFX89231.1 - 0.088 13.4 2.6 0.41 11.2 2.6 2.2 1 0 0 1 1 1 0 PAP2 superfamily C-terminal TM231 PF10149.9 KFX89231.1 - 0.38 10.1 2.1 0.57 9.5 2.1 1.2 1 0 0 1 1 1 0 Transmembrane protein 231 DUF308 PF03729.13 KFX89231.1 - 0.75 10.2 10.2 0.23 11.8 1.3 3.2 2 1 1 3 3 3 0 Short repeat of unknown function (DUF308) Arginase PF00491.21 KFX89232.1 - 7.8e-72 242.1 0.9 9e-72 241.9 0.9 1.0 1 0 0 1 1 1 1 Arginase family Kdo PF06293.14 KFX89248.1 - 1.2e-10 41.1 0.0 2e-10 40.4 0.0 1.3 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.25 KFX89248.1 - 8.4e-10 38.4 0.0 1.2e-09 37.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 KFX89248.1 - 3.3e-09 37.0 0.2 0.00041 20.3 0.1 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family Pkinase_Tyr PF07714.17 KFX89248.1 - 0.00011 21.7 0.0 0.00016 21.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.22 KFX89248.1 - 0.00052 19.7 0.0 0.0016 18.1 0.0 1.7 2 1 0 2 2 2 1 RIO1 family Pkinase_fungal PF17667.1 KFX89248.1 - 0.0027 16.5 0.0 0.0035 16.2 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Choline_kinase PF01633.20 KFX89248.1 - 0.17 11.4 0.0 0.24 11.0 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase EcKinase PF02958.20 KFX89248.1 - 0.25 10.6 0.0 0.29 10.4 0.0 1.2 1 0 0 1 1 1 0 Ecdysteroid kinase Aldo_ket_red PF00248.21 KFX89249.1 - 8.4e-09 35.0 0.0 1.3e-08 34.5 0.0 1.3 1 1 0 1 1 1 1 Aldo/keto reductase family Clat_adaptor_s PF01217.20 KFX89250.1 - 1.4e-52 177.4 1.3 1.7e-52 177.1 1.3 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain PulA_N1 PF17999.1 KFX89250.1 - 0.064 14.0 0.5 0.12 13.2 0.2 1.6 1 1 0 1 1 1 0 Pullulanase N1-terminal domain TFIIA_gamma_N PF02268.16 KFX89250.1 - 0.21 11.6 1.6 4.6 7.3 0.2 2.5 1 1 1 2 2 2 0 Transcription initiation factor IIA, gamma subunit, helical domain Maf1 PF09174.10 KFX89251.1 - 4.1e-60 202.9 0.0 5.4e-60 202.5 0.0 1.2 1 0 0 1 1 1 1 Maf1 regulator NOA36 PF06524.12 KFX89251.1 - 0.55 9.5 4.8 0.74 9.1 4.8 1.1 1 0 0 1 1 1 0 NOA36 protein Ribosomal_L7Ae PF01248.26 KFX89252.1 - 4.9e-26 90.3 0.1 5.7e-26 90.1 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RNase_P_pop3 PF08228.11 KFX89252.1 - 0.00032 20.8 0.0 0.00042 20.4 0.0 1.2 1 0 0 1 1 1 1 RNase P subunit Pop3 PELOTA_1 PF15608.6 KFX89252.1 - 0.0022 17.9 0.0 0.003 17.4 0.0 1.3 1 0 0 1 1 1 1 PELOTA RNA binding domain ATP-synt_C PF00137.21 KFX89253.1 - 8e-35 119.0 32.4 2.6e-22 78.9 13.9 2.1 2 0 0 2 2 2 2 ATP synthase subunit C CMD PF02627.20 KFX89254.1 - 1.5e-09 37.7 0.2 2e-07 31.0 0.0 2.5 3 0 0 3 3 3 2 Carboxymuconolactone decarboxylase family bZIP_1 PF00170.21 KFX89256.1 - 1.9e-08 34.3 7.8 3.6e-08 33.4 7.8 1.4 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 KFX89256.1 - 0.0057 16.7 8.0 0.0057 16.7 8.0 1.6 2 0 0 2 2 1 1 Basic region leucine zipper V_ATPase_I PF01496.19 KFX89256.1 - 0.011 13.7 0.5 0.012 13.6 0.5 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family SHE3 PF17078.5 KFX89256.1 - 0.037 13.7 4.9 0.085 12.6 4.9 1.6 1 1 0 1 1 1 0 SWI5-dependent HO expression protein 3 HAUS6_N PF14661.6 KFX89256.1 - 0.16 11.5 4.5 0.21 11.1 4.5 1.2 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus DUF4407 PF14362.6 KFX89256.1 - 0.16 11.3 3.2 0.21 10.9 3.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) GAS PF13851.6 KFX89256.1 - 0.17 11.2 8.0 0.29 10.5 8.0 1.3 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding bZIP_Maf PF03131.17 KFX89256.1 - 0.28 11.7 10.2 0.59 10.7 10.2 1.5 1 0 0 1 1 1 0 bZIP Maf transcription factor CLZ PF16526.5 KFX89256.1 - 0.29 11.5 3.4 0.56 10.6 1.9 2.0 1 1 1 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels HIP1_clath_bdg PF16515.5 KFX89256.1 - 0.33 11.6 7.1 0.55 10.9 7.1 1.3 1 0 0 1 1 1 0 Clathrin-binding domain of Huntingtin-interacting protein 1 ZapB PF06005.12 KFX89256.1 - 0.39 11.2 6.0 0.33 11.4 4.2 1.7 1 1 0 1 1 1 0 Cell division protein ZapB Ax_dynein_light PF10211.9 KFX89256.1 - 1.8 8.5 9.6 5.1 7.0 6.3 2.0 1 1 1 2 2 2 0 Axonemal dynein light chain M PF02370.16 KFX89256.1 - 3.6 8.5 6.7 3.5 8.5 0.4 2.9 2 1 0 2 2 2 0 M protein repeat H-kinase_dim PF02895.14 KFX89256.1 - 4.8 7.6 5.2 9.8 6.7 1.2 2.2 1 1 1 2 2 2 0 Signal transducing histidine kinase, homodimeric domain DivIC PF04977.15 KFX89256.1 - 8.3 6.3 8.1 4.2 7.2 1.8 2.5 1 1 1 2 2 2 0 Septum formation initiator DUF5308 PF17233.2 KFX89257.1 - 3.6e-47 160.6 2.8 4.5e-47 160.3 2.8 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF5308) AAA_11 PF13086.6 KFX89259.1 - 7.9e-60 202.8 0.1 1.4e-59 202.1 0.1 1.4 1 0 0 1 1 1 1 AAA domain AAA_12 PF13087.6 KFX89259.1 - 1.5e-55 188.0 0.0 2.3e-55 187.3 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 KFX89259.1 - 5.7e-12 45.8 0.0 1.6e-10 41.1 0.0 2.5 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KFX89259.1 - 2.7e-09 37.5 0.0 2.3e-08 34.5 0.0 2.5 3 1 0 3 3 2 1 AAA domain DUF2075 PF09848.9 KFX89259.1 - 1.3e-05 24.7 0.3 0.00011 21.6 0.2 2.3 2 1 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) ResIII PF04851.15 KFX89259.1 - 4.8e-05 23.4 0.0 0.00025 21.1 0.0 2.0 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit Viral_helicase1 PF01443.18 KFX89259.1 - 5.4e-05 23.1 0.0 0.29 10.8 0.0 3.0 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase UvrD-helicase PF00580.21 KFX89259.1 - 0.00013 21.6 0.5 0.0018 17.9 0.0 2.4 1 1 1 2 2 2 1 UvrD/REP helicase N-terminal domain AAA_22 PF13401.6 KFX89259.1 - 0.00076 19.8 0.2 0.0062 16.8 0.2 2.5 2 1 0 2 2 2 1 AAA domain DEAD PF00270.29 KFX89259.1 - 0.0016 18.3 0.0 0.0044 16.8 0.0 1.8 1 1 0 1 1 1 1 DEAD/DEAH box helicase Helicase_RecD PF05127.14 KFX89259.1 - 0.0031 17.4 0.0 0.24 11.2 0.0 2.4 2 0 0 2 2 2 1 Helicase AAA_16 PF13191.6 KFX89259.1 - 0.0047 17.3 0.1 0.011 16.1 0.1 1.8 1 1 0 1 1 1 1 AAA ATPase domain T2SSE PF00437.20 KFX89259.1 - 0.012 14.6 0.0 0.025 13.6 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein PhoH PF02562.16 KFX89259.1 - 0.016 14.7 0.0 0.24 10.8 0.0 2.2 2 0 0 2 2 2 0 PhoH-like protein AAA_25 PF13481.6 KFX89259.1 - 0.017 14.7 0.0 0.061 12.9 0.0 1.9 2 1 0 2 2 2 0 AAA domain AAA PF00004.29 KFX89259.1 - 0.023 15.1 1.4 0.085 13.3 0.0 2.5 3 1 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) Flavi_DEAD PF07652.14 KFX89259.1 - 0.027 14.4 0.0 0.072 13.1 0.0 1.7 1 0 0 1 1 1 0 Flavivirus DEAD domain AAA_24 PF13479.6 KFX89259.1 - 0.028 14.2 0.5 0.51 10.0 0.5 2.8 1 1 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 KFX89259.1 - 0.039 13.7 0.0 0.079 12.7 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein FtsK_SpoIIIE PF01580.18 KFX89259.1 - 0.041 13.2 0.5 0.94 8.8 0.0 2.5 2 1 1 3 3 3 0 FtsK/SpoIIIE family UvrD_C PF13361.6 KFX89259.1 - 0.048 13.0 0.0 8.9 5.6 0.0 2.9 3 0 0 3 3 3 0 UvrD-like helicase C-terminal domain cobW PF02492.19 KFX89259.1 - 0.088 12.4 0.0 0.24 11.0 0.0 1.7 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain SKI PF01202.22 KFX89259.1 - 0.11 12.6 0.2 0.4 10.8 0.1 1.9 1 1 1 2 2 2 0 Shikimate kinase PIF1 PF05970.14 KFX89259.1 - 0.11 11.6 0.0 5.1 6.2 0.0 2.2 2 0 0 2 2 2 0 PIF1-like helicase Mg_chelatase PF01078.21 KFX89259.1 - 0.11 11.8 0.0 0.2 11.0 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI ABC_tran PF00005.27 KFX89259.1 - 0.13 12.8 0.0 0.35 11.4 0.0 1.8 1 0 0 1 1 1 0 ABC transporter AAA_33 PF13671.6 KFX89259.1 - 0.13 12.4 0.0 0.23 11.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain UvrD_C_2 PF13538.6 KFX89259.1 - 0.15 11.9 0.0 2.1 8.3 0.0 2.4 2 0 0 2 2 2 0 UvrD-like helicase C-terminal domain adh_short PF00106.25 KFX89261.1 - 5.2e-21 75.0 0.0 1e-20 74.0 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KFX89261.1 - 1.2e-16 61.0 0.0 2.1e-16 60.2 0.0 1.4 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Asparaginase_C PF17763.1 KFX89261.1 - 0.048 13.9 0.1 0.12 12.6 0.0 1.7 1 1 0 1 1 1 0 Glutaminase/Asparaginase C-terminal domain DUF1776 PF08643.10 KFX89261.1 - 0.057 12.8 0.0 0.082 12.3 0.0 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) Nucleoporin_FG PF13634.6 KFX89264.1 - 2.9e-14 53.7 102.2 5e-05 24.1 13.8 5.1 1 1 2 4 4 4 3 Nucleoporin FG repeat region AA_permease PF00324.21 KFX89278.1 - 2.5e-34 118.7 5.1 2.8e-34 118.6 5.1 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KFX89278.1 - 9.6e-08 31.3 5.8 1.2e-07 31.0 5.6 1.3 1 1 0 1 1 1 1 Amino acid permease DUF2070 PF09843.9 KFX89278.1 - 0.03 12.6 0.6 0.037 12.3 0.6 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) MmcB-like PF06319.12 KFX89278.1 - 0.18 11.4 0.0 0.29 10.8 0.0 1.2 1 0 0 1 1 1 0 DNA repair protein MmcB-like Pneumo_att_G PF05539.11 KFX89308.1 - 7.2 6.1 8.3 7.7 6.0 8.3 1.0 1 0 0 1 1 1 0 Pneumovirinae attachment membrane glycoprotein G TRAM_LAG1_CLN8 PF03798.16 KFX89309.1 - 3.6e-37 128.0 14.6 3.6e-37 128.0 14.6 1.6 2 0 0 2 2 2 1 TLC domain TRAM1 PF08390.11 KFX89309.1 - 8.2e-22 76.6 0.1 8.2e-22 76.6 0.1 1.7 2 0 0 2 2 2 1 TRAM1-like protein SAM_2 PF07647.17 KFX89310.1 - 3.6e-14 52.6 0.0 8.5e-14 51.4 0.0 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) RA PF00788.23 KFX89310.1 - 1.6e-10 41.5 0.0 4e-10 40.2 0.0 1.7 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain SAM_1 PF00536.30 KFX89310.1 - 3.9e-10 40.0 0.0 6.4e-10 39.3 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_4 PF18017.1 KFX89310.1 - 0.11 12.5 0.0 0.19 11.7 0.0 1.3 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) C2 PF00168.30 KFX89312.1 - 1.3e-09 38.3 0.0 2.5e-09 37.3 0.0 1.5 1 0 0 1 1 1 1 C2 domain DMAP1 PF05499.12 KFX89312.1 - 0.0064 16.4 0.2 0.01 15.7 0.2 1.4 1 0 0 1 1 1 1 DNA methyltransferase 1-associated protein 1 (DMAP1) CDC45 PF02724.14 KFX89312.1 - 0.39 9.0 2.0 0.47 8.7 2.0 1.1 1 0 0 1 1 1 0 CDC45-like protein Aldo_ket_red PF00248.21 KFX89318.1 - 3.4e-40 138.1 0.0 4.1e-40 137.8 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Aldo_ket_red PF00248.21 KFX89319.1 - 1.4e-26 93.4 0.0 1.7e-26 93.1 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family CoA_transf_3 PF02515.17 KFX89321.1 - 2.1e-124 415.4 0.0 2.4e-124 415.2 0.0 1.0 1 0 0 1 1 1 1 CoA-transferase family III adh_short PF00106.25 KFX89325.1 - 2.6e-20 72.7 0.0 3.1e-20 72.5 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KFX89325.1 - 2.5e-11 43.8 0.0 3.3e-11 43.4 0.0 1.2 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.6 KFX89325.1 - 4.6e-11 42.7 0.0 5.8e-11 42.4 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Polysacc_synt_2 PF02719.15 KFX89325.1 - 0.00031 20.0 0.0 0.00037 19.7 0.0 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Epimerase PF01370.21 KFX89325.1 - 0.0047 16.4 0.0 0.0055 16.2 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Shikimate_DH PF01488.20 KFX89325.1 - 0.11 12.5 0.0 0.18 11.9 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase ALAD PF00490.21 KFX89326.1 - 1.5e-119 398.9 0.0 1.9e-119 398.6 0.0 1.1 1 0 0 1 1 1 1 Delta-aminolevulinic acid dehydratase PAPA-1 PF04795.12 KFX89327.1 - 1.3e-06 29.1 11.0 1.3e-06 29.1 11.0 3.8 4 1 0 4 4 4 1 PAPA-1-like conserved region NUDIX PF00293.28 KFX89328.1 - 0.0067 16.5 0.0 0.018 15.1 0.0 1.8 1 1 0 1 1 1 1 NUDIX domain PGA2 PF07543.12 KFX89335.1 - 1.9e-37 128.3 2.8 2.4e-37 128.0 2.8 1.1 1 0 0 1 1 1 1 Protein trafficking PGA2 FliT PF05400.13 KFX89335.1 - 0.015 16.1 1.2 0.015 16.1 1.2 1.9 2 1 1 3 3 3 0 Flagellar protein FliT VIR_N PF15912.5 KFX89335.1 - 0.23 11.0 1.9 0.29 10.7 1.9 1.1 1 0 0 1 1 1 0 Virilizer, N-terminal ZZ PF00569.17 KFX89336.1 - 0.43 10.4 1.8 3.6 7.5 0.2 2.8 3 0 0 3 3 3 0 Zinc finger, ZZ type SpoIIE PF07228.12 KFX89338.1 - 1.9e-05 24.7 0.0 4.9e-05 23.3 0.0 1.7 1 1 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) PP2C PF00481.21 KFX89338.1 - 7.4e-05 22.5 0.0 0.031 13.9 0.0 2.1 2 0 0 2 2 2 2 Protein phosphatase 2C Fcf1 PF04900.12 KFX89339.1 - 1.6e-32 111.9 0.0 2.4e-32 111.3 0.0 1.3 1 0 0 1 1 1 1 Fcf1 CTP_transf_like PF01467.26 KFX89345.1 - 9.7e-10 38.8 0.0 1.1e-09 38.7 0.0 1.0 1 0 0 1 1 1 1 Cytidylyltransferase-like Extensin_2 PF04554.13 KFX89347.1 - 0.075 13.1 7.3 51 4.1 7.3 3.3 1 1 0 1 1 1 0 Extensin-like region Molydop_binding PF01568.21 KFX89347.1 - 0.13 12.2 0.4 1.4 9.0 0.1 2.1 1 1 1 2 2 2 0 Molydopterin dinucleotide binding domain CoA_binding_2 PF13380.6 KFX89347.1 - 0.2 12.1 1.9 78 3.8 0.1 3.0 1 1 3 4 4 4 0 CoA binding domain DUF2025 PF09634.10 KFX89347.1 - 1 9.4 3.1 23 5.1 0.0 3.6 1 1 4 5 5 5 0 Protein of unknown function (DUF2025) Vps54 PF07928.12 KFX89348.1 - 4.2e-46 156.7 0.0 2.6e-45 154.1 0.0 2.1 2 0 0 2 2 2 1 Vps54-like protein Vps54_N PF10475.9 KFX89348.1 - 4.9e-06 26.0 1.6 1.1e-05 24.8 0.2 2.1 2 0 0 2 2 2 1 Vacuolar-sorting protein 54, of GARP complex DUF2451 PF10474.9 KFX89348.1 - 0.016 15.0 0.0 0.055 13.2 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function C-terminus (DUF2451) DUF4055 PF13264.6 KFX89348.1 - 0.14 12.3 0.4 0.38 10.9 0.4 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4055) MCM PF00493.23 KFX89349.1 - 3.2e-105 350.2 0.3 1.2e-104 348.3 0.0 1.9 2 0 0 2 2 2 1 MCM P-loop domain MCM_OB PF17207.3 KFX89349.1 - 2.2e-34 118.0 0.4 4.5e-34 117.0 0.4 1.5 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 KFX89349.1 - 4.3e-31 107.2 0.8 9.9e-31 106.0 0.8 1.6 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 KFX89349.1 - 8.7e-15 55.2 0.2 2e-14 54.0 0.2 1.6 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 KFX89349.1 - 9.6e-08 31.6 0.1 6.2e-05 22.5 0.0 2.3 1 1 1 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 KFX89349.1 - 8.9e-05 22.5 0.0 0.00018 21.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 KFX89349.1 - 0.00038 20.3 0.0 0.0015 18.4 0.0 2.0 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 KFX89349.1 - 0.0058 16.4 0.1 2.5 7.8 0.0 2.5 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA PF00004.29 KFX89349.1 - 0.046 14.1 0.0 0.12 12.8 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KFX89349.1 - 0.11 12.9 0.9 0.86 10.0 0.2 2.6 2 1 0 2 2 2 0 AAA ATPase domain DUF1048 PF06304.11 KFX89350.1 - 0.0083 16.6 0.0 0.0096 16.4 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1048) DUF5100 PF17029.5 KFX89350.1 - 0.042 13.7 0.0 0.049 13.5 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF5100) Glyco_transf_8 PF01501.20 KFX89352.1 - 0.015 14.9 0.0 0.02 14.4 0.0 1.2 1 0 0 1 1 1 0 Glycosyl transferase family 8 Aminotran_1_2 PF00155.21 KFX89360.1 - 9.2e-37 127.1 0.0 1.5e-36 126.4 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II DXP_synthase_N PF13292.6 KFX89360.1 - 0.0087 15.3 0.0 0.014 14.6 0.0 1.2 1 0 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase Cys_Met_Meta_PP PF01053.20 KFX89360.1 - 0.14 10.7 0.0 0.23 9.9 0.0 1.3 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme RPN7 PF10602.9 KFX89361.1 - 9.3e-59 198.0 0.4 1.4e-58 197.4 0.4 1.3 1 0 0 1 1 1 1 26S proteasome subunit RPN7 PCI PF01399.27 KFX89361.1 - 1.8e-13 50.9 0.0 3.8e-13 49.9 0.0 1.5 1 0 0 1 1 1 1 PCI domain VirionAssem_T7 PF11653.8 KFX89361.1 - 0.15 12.6 0.7 0.32 11.5 0.0 1.9 2 0 0 2 2 2 0 Bacteriophage T7 virion assembly protein SUR7 PF06687.12 KFX89370.1 - 9e-30 103.9 7.6 1.3e-29 103.4 7.6 1.1 1 0 0 1 1 1 1 SUR7/PalI family Trp_oprn_chp PF09534.10 KFX89370.1 - 0.1 12.4 2.9 0.24 11.2 0.8 2.0 2 0 0 2 2 2 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) DUF4064 PF13273.6 KFX89370.1 - 0.52 10.6 7.2 0.64 10.3 0.0 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF4064) Cyt_c_ox_IV PF12270.8 KFX89370.1 - 5.8 7.1 9.2 0.83 9.8 3.4 2.2 2 0 0 2 2 2 0 Cytochrome c oxidase subunit IV Carbam_trans_C PF16861.5 KFX89372.1 - 4.5e-69 231.4 0.0 5.1e-69 231.2 0.0 1.0 1 0 0 1 1 1 1 Carbamoyltransferase C-terminus DUF3602 PF12223.8 KFX89384.1 - 1e-15 58.0 13.2 3.7e-13 49.9 5.6 2.5 1 1 1 2 2 2 2 Protein of unknown function (DUF3602) DUF4614 PF15391.6 KFX89384.1 - 0.12 12.4 5.4 0.15 12.0 5.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4614) CytochromB561_N PF09786.9 KFX89384.1 - 0.25 10.3 4.3 0.26 10.2 4.3 1.0 1 0 0 1 1 1 0 Cytochrome B561, N terminal Macoilin PF09726.9 KFX89384.1 - 2.7 6.4 4.5 2.8 6.4 4.5 1.0 1 0 0 1 1 1 0 Macoilin family GHMP_kinases_N PF00288.26 KFX89386.1 - 0.0012 19.0 0.2 0.0058 16.8 0.0 2.1 2 0 0 2 2 2 1 GHMP kinases N terminal domain Zn_clus PF00172.18 KFX89387.1 - 2.6e-05 24.2 10.6 2.6e-05 24.2 10.6 2.0 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 KFX89387.1 - 9.8e-05 21.3 2.0 0.00025 20.0 0.2 2.0 2 0 0 2 2 2 1 Fungal specific transcription factor domain WAPL PF07814.13 KFX89387.1 - 0.039 12.8 0.5 0.06 12.1 0.5 1.2 1 0 0 1 1 1 0 Wings apart-like protein regulation of heterochromatin Sugar_tr PF00083.24 KFX89388.1 - 2.4e-79 267.3 27.0 2.9e-79 267.1 27.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KFX89388.1 - 4.8e-27 94.8 26.0 4.8e-27 94.8 26.0 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 KFX89388.1 - 0.00037 19.1 2.4 0.00037 19.1 2.4 1.8 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) p450 PF00067.22 KFX89389.1 - 4.4e-59 200.4 0.0 5.8e-59 200.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Aldose_epim PF01263.20 KFX89390.1 - 2e-57 194.8 0.0 2.7e-57 194.4 0.0 1.1 1 0 0 1 1 1 1 Aldose 1-epimerase HpcH_HpaI PF03328.14 KFX89391.1 - 1.3e-31 109.5 0.0 1.8e-31 109.0 0.0 1.1 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family ADH_zinc_N PF00107.26 KFX89391.1 - 0.042 13.8 2.0 5.9 6.9 0.3 3.3 1 1 2 3 3 3 0 Zinc-binding dehydrogenase adh_short_C2 PF13561.6 KFX89392.1 - 1.2e-36 126.4 1.7 7.7e-36 123.8 1.7 1.8 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KFX89392.1 - 8.9e-34 116.6 1.4 8e-33 113.5 0.1 2.5 2 1 0 2 2 2 1 short chain dehydrogenase KR PF08659.10 KFX89392.1 - 0.00034 20.6 0.1 0.00055 19.9 0.1 1.3 1 0 0 1 1 1 1 KR domain GDP_Man_Dehyd PF16363.5 KFX89392.1 - 0.13 11.7 1.6 2.4 7.4 0.8 3.0 2 1 0 2 2 2 0 GDP-mannose 4,6 dehydratase HORMA PF02301.18 KFX89396.1 - 1.7e-32 112.8 0.0 2.9e-32 112.0 0.0 1.4 1 0 0 1 1 1 1 HORMA domain PHD PF00628.29 KFX89396.1 - 0.0099 15.8 10.6 0.021 14.7 10.6 1.5 1 0 0 1 1 1 1 PHD-finger C1_1 PF00130.22 KFX89396.1 - 0.057 13.3 5.4 0.12 12.3 5.4 1.5 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) PHD_2 PF13831.6 KFX89396.1 - 0.082 12.5 4.6 0.14 11.7 4.6 1.4 1 0 0 1 1 1 0 PHD-finger Stc1 PF12898.7 KFX89396.1 - 1.3 9.6 6.8 0.73 10.4 4.1 2.0 2 0 0 2 2 2 0 Stc1 domain Trp_halogenase PF04820.14 KFX89397.1 - 3.2e-13 49.4 0.1 1.2e-05 24.3 0.0 2.4 1 1 1 2 2 2 2 Tryptophan halogenase Thi4 PF01946.17 KFX89397.1 - 0.00047 19.5 0.1 0.0056 15.9 0.0 2.2 2 1 0 2 2 2 1 Thi4 family DAO PF01266.24 KFX89397.1 - 0.00094 18.9 0.0 0.0014 18.3 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Mqo PF06039.15 KFX89397.1 - 0.0012 17.4 0.0 0.0017 17.0 0.0 1.1 1 0 0 1 1 1 1 Malate:quinone oxidoreductase (Mqo) NAD_binding_8 PF13450.6 KFX89397.1 - 0.0099 16.1 0.0 0.026 14.7 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 KFX89397.1 - 0.021 15.4 0.0 0.14 12.8 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase PsaF PF17550.2 KFX89397.1 - 0.09 12.3 0.2 0.19 11.2 0.0 1.6 2 0 0 2 2 2 0 Family of unknown function Lycopene_cycl PF05834.12 KFX89397.1 - 0.18 10.8 0.0 3 6.8 0.0 2.1 2 0 0 2 2 2 0 Lycopene cyclase protein CAS_CSE1 PF03378.15 KFX89402.1 - 2.2e-21 75.9 0.0 2.6e-21 75.7 0.0 1.0 1 0 0 1 1 1 1 CAS/CSE protein, C-terminus DUF1640 PF07798.11 KFX89403.1 - 2.2e-39 135.3 9.8 2.2e-39 135.3 9.8 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF1640) MSC PF09402.10 KFX89403.1 - 0.39 10.1 8.1 0.54 9.7 8.1 1.1 1 0 0 1 1 1 0 Man1-Src1p-C-terminal domain GPHR_N PF12537.8 KFX89407.1 - 0.03 14.4 0.0 0.046 13.8 0.0 1.4 1 1 0 1 1 1 0 The Golgi pH Regulator (GPHR) Family N-terminal AA_permease PF00324.21 KFX89417.1 - 1e-91 307.9 25.5 1.2e-91 307.8 25.5 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KFX89417.1 - 2.5e-30 105.7 32.8 3.2e-30 105.3 32.8 1.0 1 0 0 1 1 1 1 Amino acid permease DUF3593 PF12159.8 KFX89417.1 - 0.069 13.2 2.3 3.6 7.7 0.1 3.3 2 1 1 3 3 3 0 Protein of unknown function (DUF3593) Claudin_3 PF06653.11 KFX89417.1 - 7.3 6.5 13.4 0.97 9.4 0.6 3.0 3 1 0 3 3 3 0 Tight junction protein, Claudin-like Fungal_trans_2 PF11951.8 KFX89454.1 - 8.3e-08 31.4 0.6 1.7e-07 30.4 0.6 1.4 1 1 0 1 1 1 1 Fungal specific transcription factor domain STE PF02200.16 KFX89456.1 - 2.2e-56 189.0 0.3 4.1e-56 188.1 0.1 1.6 2 0 0 2 2 2 1 STE like transcription factor SUIM_assoc PF16619.5 KFX89456.1 - 0.043 13.9 11.5 0.078 13.0 10.1 2.3 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 DUF1059 PF06348.11 KFX89456.1 - 0.2 11.9 0.0 0.48 10.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1059) TFIIA PF03153.13 KFX89456.1 - 1 9.3 17.7 1.7 8.6 17.7 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PAT1 PF09770.9 KFX89456.1 - 6.2 5.0 18.9 8.1 4.6 18.9 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Med16 PF11635.8 KFX89461.1 - 2.9e-65 220.6 0.0 3.6e-65 220.3 0.0 1.0 1 0 0 1 1 1 1 Mediator complex subunit 16 p450 PF00067.22 KFX89463.1 - 8.4e-82 275.3 0.0 9.9e-82 275.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 ABC2_membrane_5 PF13346.6 KFX89463.1 - 0.0042 16.7 0.2 0.008 15.8 0.2 1.4 1 0 0 1 1 1 1 ABC-2 family transporter protein ASL_C PF08328.11 KFX89463.1 - 0.11 12.6 0.3 0.25 11.4 0.1 1.7 2 0 0 2 2 2 0 Adenylosuccinate lyase C-terminal Arf PF00025.21 KFX89465.1 - 3.3e-44 150.4 0.0 3.8e-44 150.2 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.22 KFX89465.1 - 1.5e-18 67.0 0.0 1.7e-18 66.8 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFX89465.1 - 5.6e-16 58.9 0.0 7.8e-16 58.4 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 KFX89465.1 - 3.9e-08 32.9 0.0 4.6e-08 32.7 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 KFX89465.1 - 1e-06 28.8 0.0 1.5e-06 28.3 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 KFX89465.1 - 9.6e-06 25.1 0.0 1.2e-05 24.8 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region G-alpha PF00503.20 KFX89465.1 - 0.0003 20.1 0.3 0.0016 17.7 0.1 2.0 1 1 1 2 2 2 1 G-protein alpha subunit FeoB_N PF02421.18 KFX89465.1 - 0.011 15.2 0.2 0.038 13.5 0.2 2.1 1 1 0 1 1 1 0 Ferrous iron transport protein B Dynamin_N PF00350.23 KFX89465.1 - 0.065 13.3 0.0 0.37 10.8 0.1 1.9 1 1 1 2 2 2 0 Dynamin family NACHT PF05729.12 KFX89465.1 - 0.11 12.4 0.4 0.31 10.9 0.0 1.8 2 0 0 2 2 2 0 NACHT domain PduV-EutP PF10662.9 KFX89465.1 - 0.14 11.9 0.1 2.1 8.1 0.0 2.3 2 1 1 3 3 3 0 Ethanolamine utilisation - propanediol utilisation MMR_HSR1_Xtn PF16897.5 KFX89465.1 - 0.16 12.0 0.0 0.27 11.3 0.0 1.4 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain RCR PF12273.8 KFX89466.1 - 9.6e-22 77.9 7.6 1.4e-21 77.4 7.6 1.2 1 0 0 1 1 1 1 Chitin synthesis regulation, resistance to Congo red Acyl_transf_3 PF01757.22 KFX89466.1 - 0.052 12.6 0.2 0.066 12.3 0.2 1.1 1 0 0 1 1 1 0 Acyltransferase family Fungal_KA1 PF16797.5 KFX89470.1 - 2.1e-38 130.7 0.1 2.8e-38 130.2 0.1 1.2 1 0 0 1 1 1 1 Fungal kinase associated-1 domain MSA-2c PF12238.8 KFX89470.1 - 0.1 12.6 6.3 0.16 11.9 6.3 1.3 1 0 0 1 1 1 0 Merozoite surface antigen 2c Cerato-platanin PF07249.12 KFX89471.1 - 6.1e-49 165.1 1.0 7.1e-49 164.9 1.0 1.0 1 0 0 1 1 1 1 Cerato-platanin FOG_N PF15888.5 KFX89471.1 - 0.11 12.9 0.0 0.27 11.6 0.0 1.6 2 0 0 2 2 2 0 Folded gastrulation N-terminus Alginate_lyase PF05426.12 KFX89472.1 - 2.6e-13 50.2 3.4 2.9e-12 46.7 3.4 2.1 1 1 0 1 1 1 1 Alginate lyase Alginate_lyase2 PF08787.11 KFX89474.1 - 2.5e-41 142.1 0.0 2.8e-41 141.9 0.0 1.0 1 0 0 1 1 1 1 Alginate lyase Glyco_hydro_7 PF00840.20 KFX89475.1 - 1.2e-199 663.6 20.0 1.3e-199 663.4 20.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 7 NRBF2_MIT PF17169.4 KFX89477.1 - 0.17 12.1 1.6 0.23 11.7 1.6 1.2 1 0 0 1 1 1 0 MIT domain of nuclear receptor-binding factor 2 GRAM PF02893.20 KFX89478.1 - 1e-23 83.4 0.0 1.8e-23 82.6 0.0 1.5 1 0 0 1 1 1 1 GRAM domain VASt PF16016.5 KFX89478.1 - 7.5e-12 45.9 0.0 1.4e-11 45.0 0.0 1.4 1 0 0 1 1 1 1 VAD1 Analog of StAR-related lipid transfer domain FRG2 PF15315.6 KFX89492.1 - 0.16 12.2 0.4 0.21 11.8 0.4 1.1 1 0 0 1 1 1 0 Facioscapulohumeral muscular dystrophy candidate 2 FACT-Spt16_Nlob PF14826.6 KFX89498.1 - 7.7e-56 188.3 0.1 2.4e-55 186.8 0.1 1.9 1 0 0 1 1 1 1 FACT complex subunit SPT16 N-terminal lobe domain SPT16 PF08644.11 KFX89498.1 - 3.1e-55 186.5 0.1 3.1e-55 186.5 0.1 2.8 3 0 0 3 3 3 1 FACT complex subunit (SPT16/CDC68) Peptidase_M24 PF00557.24 KFX89498.1 - 2.2e-24 86.3 0.0 4e-24 85.5 0.0 1.4 1 0 0 1 1 1 1 Metallopeptidase family M24 Rtt106 PF08512.12 KFX89498.1 - 6.2e-15 55.4 0.4 1.9e-14 53.9 0.0 2.0 2 0 0 2 2 2 1 Histone chaperone Rttp106-like DUF2462 PF09495.10 KFX89499.1 - 3.1e-21 75.9 8.5 3.1e-21 75.9 8.5 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF2462) ERG4_ERG24 PF01222.17 KFX89500.1 - 3.4e-138 461.0 17.1 3.9e-138 460.8 17.1 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family SRP-alpha_N PF04086.13 KFX89500.1 - 2 8.2 6.0 2.9 7.7 6.0 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal SET PF00856.28 KFX89509.1 - 9.1e-21 75.0 0.1 2.6e-20 73.5 0.0 1.8 2 0 0 2 2 2 1 SET domain Rubis-subs-bind PF09273.11 KFX89509.1 - 2.9e-11 44.2 0.7 2.9e-11 44.2 0.7 2.0 2 0 0 2 2 2 1 Rubisco LSMT substrate-binding DUF4484 PF14831.6 KFX89509.1 - 0.12 12.5 2.3 0.12 12.3 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4484) EPL1 PF10513.9 KFX89510.1 - 8e-22 78.3 5.1 8e-22 78.3 5.1 2.0 2 1 0 2 2 2 1 Enhancer of polycomb-like EF-hand_1 PF00036.32 KFX89511.1 - 7.2e-27 90.9 9.8 3.4e-07 29.3 0.6 4.3 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 KFX89511.1 - 1e-23 83.6 13.4 4.7e-14 52.6 1.0 3.0 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_6 PF13405.6 KFX89511.1 - 1.9e-21 74.1 5.1 2e-05 24.2 0.1 4.4 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 KFX89511.1 - 7.8e-20 69.4 8.8 1.1e-06 27.9 0.3 4.3 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.6 KFX89511.1 - 2.2e-14 53.0 8.6 3.7e-05 23.5 0.4 4.1 2 1 2 4 4 4 4 EF-hand domain pair SPARC_Ca_bdg PF10591.9 KFX89511.1 - 8.5e-07 29.3 0.0 0.0034 17.7 0.0 2.3 2 1 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 KFX89511.1 - 2.6e-06 27.3 7.6 0.0028 17.6 0.4 3.9 1 1 3 4 4 4 2 Cytoskeletal-regulatory complex EF hand Dockerin_1 PF00404.18 KFX89511.1 - 0.023 14.9 0.7 0.1 12.8 0.7 2.2 1 1 0 1 1 1 0 Dockerin type I domain COQ7 PF03232.13 KFX89520.1 - 0.062 13.1 0.0 0.086 12.6 0.0 1.2 1 0 0 1 1 1 0 Ubiquinone biosynthesis protein COQ7 CDP-OH_P_transf PF01066.21 KFX89526.1 - 2.8e-14 53.6 0.1 5.6e-14 52.7 0.1 1.5 1 0 0 1 1 1 1 CDP-alcohol phosphatidyltransferase Metallopep PF12044.8 KFX89527.1 - 1.4e-165 551.1 0.0 1.7e-165 550.8 0.0 1.1 1 0 0 1 1 1 1 Putative peptidase family Reprolysin_5 PF13688.6 KFX89527.1 - 0.04 14.1 1.9 0.087 13.0 1.9 1.5 1 1 0 1 1 1 0 Metallo-peptidase family M12 Jacalin PF01419.17 KFX89527.1 - 0.041 13.8 0.0 0.32 10.9 0.0 2.2 1 1 0 1 1 1 0 Jacalin-like lectin domain HSP70 PF00012.20 KFX89533.1 - 2.8e-10 39.1 0.2 1.2e-08 33.7 0.0 2.0 2 0 0 2 2 2 2 Hsp70 protein FtsA PF14450.6 KFX89533.1 - 0.0065 16.9 0.6 0.14 12.6 0.0 2.5 2 0 0 2 2 2 1 Cell division protein FtsA DNA_pol_lambd_f PF10391.9 KFX89533.1 - 0.14 12.0 0.0 0.3 11.0 0.0 1.5 1 0 0 1 1 1 0 Fingers domain of DNA polymerase lambda Vps5 PF09325.10 KFX89539.1 - 0.022 14.3 0.0 0.033 13.7 0.0 1.1 1 0 0 1 1 1 0 Vps5 C terminal like Peptidase_S7 PF00949.21 KFX89542.1 - 0.066 13.0 0.0 0.23 11.3 0.0 1.9 1 1 1 2 2 2 0 Peptidase S7, Flavivirus NS3 serine protease Peptidase_S64 PF08192.11 KFX89542.1 - 0.16 10.4 0.2 0.31 9.5 0.2 1.4 1 0 0 1 1 1 0 Peptidase family S64 DENN PF02141.21 KFX89543.1 - 7.1e-40 136.9 0.0 1.2e-39 136.2 0.0 1.4 1 0 0 1 1 1 1 DENN (AEX-3) domain uDENN PF03456.18 KFX89543.1 - 3.5e-06 27.7 0.0 1.2e-05 25.9 0.0 2.0 1 0 0 1 1 1 1 uDENN domain MCC-bdg_PDZ PF10506.9 KFX89543.1 - 0.009 16.0 2.3 0.18 11.9 2.0 2.9 2 0 0 2 2 2 1 PDZ domain of MCC-2 bdg protein for Usher syndrome Queuosine_synth PF02547.15 KFX89543.1 - 0.02 14.0 0.5 0.037 13.2 0.5 1.3 1 0 0 1 1 1 0 Queuosine biosynthesis protein Glyco_hydro_108 PF05838.12 KFX89543.1 - 0.1 13.1 0.0 0.72 10.4 0.0 2.3 2 0 0 2 2 2 0 Glycosyl hydrolase 108 Elongin_A PF06881.11 KFX89543.1 - 0.89 10.1 10.3 0.03 14.8 3.3 2.2 2 0 0 2 2 2 0 RNA polymerase II transcription factor SIII (Elongin) subunit A Cnn_1N PF07989.11 KFX89543.1 - 2.6 8.3 13.7 0.59 10.3 2.2 2.6 2 0 0 2 2 2 0 Centrosomin N-terminal motif 1 TMF_TATA_bd PF12325.8 KFX89543.1 - 4.3 7.6 16.8 16 5.8 5.7 3.3 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding BRE1 PF08647.11 KFX89543.1 - 7.2 6.8 17.8 0.23 11.5 6.8 2.7 1 1 1 2 2 2 0 BRE1 E3 ubiquitin ligase CDC45 PF02724.14 KFX89545.1 - 7 4.8 5.3 7.2 4.8 5.3 1.0 1 0 0 1 1 1 0 CDC45-like protein Aminotran_5 PF00266.19 KFX89546.1 - 1.1e-14 54.1 0.0 1.3e-14 53.9 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Ala_racemase_N PF01168.20 KFX89549.1 - 1.1e-23 84.0 0.0 1.4e-23 83.7 0.0 1.0 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain Cupin_2 PF07883.11 KFX89551.1 - 3e-20 71.7 0.3 2.4e-09 36.8 0.1 2.2 2 0 0 2 2 2 2 Cupin domain Cupin_3 PF05899.12 KFX89551.1 - 5.8e-17 61.2 1.7 8.7e-14 51.0 0.5 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF861) AraC_binding PF02311.19 KFX89551.1 - 6.9e-06 26.0 0.1 0.035 14.0 0.0 2.2 2 0 0 2 2 2 2 AraC-like ligand binding domain CENP-C_C PF11699.8 KFX89551.1 - 0.0003 20.9 0.0 0.00086 19.5 0.0 1.7 2 0 0 2 2 2 1 Mif2/CENP-C like Mrx7 PF10906.8 KFX89551.1 - 0.053 13.8 0.0 0.11 12.8 0.0 1.5 1 0 0 1 1 1 0 MIOREX complex component 7 Sugar_tr PF00083.24 KFX89559.1 - 3.8e-76 256.8 21.9 3.8e-76 256.8 21.9 2.4 2 0 0 2 2 2 1 Sugar (and other) transporter NmrA PF05368.13 KFX89559.1 - 4.1e-28 98.5 0.0 9.1e-28 97.4 0.0 1.6 1 0 0 1 1 1 1 NmrA-like family ArAE_2_N PF10337.9 KFX89559.1 - 2.1e-22 79.8 22.0 8.7e-22 77.8 9.3 3.5 2 1 0 2 2 2 1 Putative ER transporter, 6TM, N-terminal NAD_binding_10 PF13460.6 KFX89559.1 - 1.5e-12 47.8 0.0 2.5e-12 47.1 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding FUSC_2 PF13515.6 KFX89559.1 - 1.5e-11 44.5 21.9 1.5e-11 44.5 21.9 5.5 5 2 0 5 5 5 1 Fusaric acid resistance protein-like MFS_1 PF07690.16 KFX89559.1 - 5.5e-11 42.0 45.1 1.5e-10 40.6 17.1 4.5 2 2 1 3 3 3 2 Major Facilitator Superfamily Epimerase PF01370.21 KFX89559.1 - 0.0013 18.2 0.0 0.0023 17.4 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.10 KFX89559.1 - 0.0052 16.7 0.2 0.017 15.1 0.0 1.8 2 0 0 2 2 2 1 KR domain Sacchrp_dh_NADP PF03435.18 KFX89559.1 - 0.023 14.9 0.0 0.045 14.0 0.0 1.4 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Amidohydro_2 PF04909.14 KFX89560.1 - 1.7e-20 74.0 0.0 2e-20 73.7 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase Fungal_trans PF04082.18 KFX89561.1 - 9.6e-26 90.4 3.2 1.8e-25 89.5 3.2 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KFX89561.1 - 8.1e-10 38.7 9.2 1.6e-09 37.7 9.2 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pox_F15 PF04596.12 KFX89561.1 - 0.045 13.5 0.1 0.11 12.3 0.1 1.5 1 0 0 1 1 1 0 Poxvirus protein F15 Hid1 PF12722.7 KFX89562.1 - 2.3e-297 988.6 0.0 2.6e-297 988.4 0.0 1.0 1 0 0 1 1 1 1 High-temperature-induced dauer-formation protein Dymeclin PF09742.9 KFX89562.1 - 3.2e-104 349.6 0.0 3.8e-104 349.4 0.0 1.0 1 0 0 1 1 1 1 Dyggve-Melchior-Clausen syndrome protein TPR_10 PF13374.6 KFX89568.1 - 2.7e-96 313.2 0.0 5.3e-13 48.4 0.0 9.8 9 0 0 9 9 9 9 Tetratricopeptide repeat TPR_12 PF13424.6 KFX89568.1 - 1.7e-79 262.1 4.3 7.3e-17 61.4 0.0 8.5 2 2 6 8 8 8 8 Tetratricopeptide repeat SesA PF17107.5 KFX89568.1 - 6.4e-35 120.0 0.7 6.4e-35 120.0 0.7 2.6 3 0 0 3 3 2 1 N-terminal domain on NACHT_NTPase and P-loop NTPases TPR_7 PF13176.6 KFX89568.1 - 1.1e-23 81.5 0.6 0.0001 22.1 0.0 7.8 7 0 0 7 7 6 5 Tetratricopeptide repeat TPR_17 PF13431.6 KFX89568.1 - 1.1e-13 50.6 5.2 0.82 10.2 0.0 7.7 8 0 0 8 8 8 4 Tetratricopeptide repeat TPR_1 PF00515.28 KFX89568.1 - 3.1e-11 42.6 6.4 0.029 14.2 0.0 7.3 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_2 PF07719.17 KFX89568.1 - 1.3e-08 34.3 11.7 0.095 12.9 0.0 8.7 10 0 0 10 10 9 2 Tetratricopeptide repeat TPR_MalT PF17874.1 KFX89568.1 - 2e-08 34.0 5.2 6.3e-06 25.8 0.1 3.2 1 1 2 3 3 3 2 MalT-like TPR region TPR_4 PF07721.14 KFX89568.1 - 6.4e-08 32.5 8.6 1.4 9.8 0.1 6.7 8 0 0 8 8 6 3 Tetratricopeptide repeat TPR_16 PF13432.6 KFX89568.1 - 1.2e-07 32.2 0.3 2 9.1 0.0 7.1 8 0 0 8 8 7 1 Tetratricopeptide repeat NB-ARC PF00931.22 KFX89568.1 - 8.3e-07 28.4 1.5 0.0001 21.6 0.0 3.5 3 2 0 4 4 4 1 NB-ARC domain TPR_19 PF14559.6 KFX89568.1 - 1.2e-05 25.7 8.2 5 7.7 0.0 7.4 5 2 3 8 8 8 1 Tetratricopeptide repeat TPR_8 PF13181.6 KFX89568.1 - 0.0068 16.5 17.3 1.1 9.7 0.0 8.3 10 0 0 10 10 8 1 Tetratricopeptide repeat AAA_24 PF13479.6 KFX89568.1 - 0.017 14.8 0.0 0.14 11.8 0.0 2.6 3 0 0 3 3 3 0 AAA domain AAA_22 PF13401.6 KFX89568.1 - 0.019 15.2 0.0 0.11 12.8 0.0 2.3 2 1 0 2 2 2 0 AAA domain Translin PF01997.16 KFX89568.1 - 0.029 14.3 0.1 0.056 13.4 0.1 1.5 1 0 0 1 1 1 0 Translin family SNAP PF14938.6 KFX89568.1 - 0.03 13.8 0.1 1.2 8.5 0.0 2.9 2 1 1 3 3 3 0 Soluble NSF attachment protein, SNAP AAA_25 PF13481.6 KFX89568.1 - 0.043 13.4 0.0 0.18 11.4 0.0 2.0 2 0 0 2 2 2 0 AAA domain Spore_III_AB PF09548.10 KFX89568.1 - 0.046 13.8 0.9 0.18 11.9 0.5 2.2 3 0 0 3 3 3 0 Stage III sporulation protein AB (spore_III_AB) Helo_like_N PF17111.5 KFX89568.1 - 0.076 12.4 0.0 1.1 8.6 0.0 2.4 2 0 0 2 2 2 0 Fungal N-terminal domain of STAND proteins PPR PF01535.20 KFX89568.1 - 0.31 11.4 9.5 9.9 6.7 0.0 6.7 8 0 0 8 8 7 0 PPR repeat MFS_2 PF13347.6 KFX89572.1 - 6.4e-11 41.5 18.7 3.3e-10 39.1 14.0 2.4 3 0 0 3 3 3 2 MFS/sugar transport protein MFS_1_like PF12832.7 KFX89572.1 - 0.023 13.6 5.9 0.0062 15.4 1.9 2.1 2 1 0 2 2 2 0 MFS_1 like family DUF1752 PF08550.10 KFX89579.1 - 5.1e-10 39.0 4.1 9.7e-10 38.1 4.1 1.5 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) DUF4813 PF16072.5 KFX89579.1 - 7.5 6.1 12.8 0.034 13.8 1.9 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4813) RhoGAP PF00620.27 KFX89581.1 - 9.3e-42 142.4 0.0 2e-41 141.4 0.0 1.5 1 0 0 1 1 1 1 RhoGAP domain JIP_LZII PF16471.5 KFX89581.1 - 0.92 9.7 7.4 0.082 13.1 1.8 2.2 2 0 0 2 2 2 0 JNK-interacting protein leucine zipper II zf-H2C2_2 PF13465.6 KFX89599.1 - 8.2e-06 26.0 0.5 8.2e-06 26.0 0.5 3.9 4 0 0 4 4 4 1 Zinc-finger double domain zf-C2H2 PF00096.26 KFX89599.1 - 1.5e-05 25.2 9.6 4.9e-05 23.6 0.2 3.7 3 1 0 3 3 3 1 Zinc finger, C2H2 type FOXP-CC PF16159.5 KFX89599.1 - 4.7e-05 23.9 4.5 0.52 11.0 2.6 3.4 2 1 1 3 3 3 2 FOXP coiled-coil domain zf-C2H2_6 PF13912.6 KFX89599.1 - 8.6e-05 22.4 0.2 0.24 11.4 0.0 2.4 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_4 PF13894.6 KFX89599.1 - 0.0009 19.9 6.9 0.045 14.6 0.2 3.7 3 0 0 3 3 3 1 C2H2-type zinc finger zf-C2H2_11 PF16622.5 KFX89599.1 - 0.0035 17.1 0.3 0.016 14.9 0.0 2.1 2 0 0 2 2 2 1 zinc-finger C2H2-type zf-C2H2_3rep PF18868.1 KFX89599.1 - 0.047 14.4 1.3 3.3 8.4 0.4 2.7 2 1 1 3 3 3 0 Zinc finger C2H2-type, 3 repeats zf-C2H2_jaz PF12171.8 KFX89599.1 - 0.31 11.4 0.9 18 5.7 0.0 3.1 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding Aldo_ket_red PF00248.21 KFX89600.1 - 7.9e-57 192.7 0.0 9e-57 192.5 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family WD40 PF00400.32 KFX89601.1 - 1e-22 79.9 6.6 6.9e-07 29.9 0.1 6.4 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFX89601.1 - 1.4e-15 57.4 0.1 0.099 13.0 0.0 6.0 1 1 5 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KFX89601.1 - 0.00013 20.8 0.1 0.017 13.8 0.1 2.2 1 1 1 2 2 2 2 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.16 KFX89601.1 - 0.019 13.5 0.0 1.6 7.2 0.0 2.2 1 1 0 2 2 2 0 Cytochrome D1 heme domain HRXXH PF13933.6 KFX89603.1 - 2.3e-95 318.8 0.0 2.9e-95 318.5 0.0 1.1 1 0 0 1 1 1 1 Putative peptidase family Aspzincin_M35 PF14521.6 KFX89603.1 - 1.2e-06 29.1 0.0 2.4e-06 28.2 0.0 1.4 1 0 0 1 1 1 1 Lysine-specific metallo-endopeptidase Zip PF02535.22 KFX89604.1 - 5.2e-40 137.7 13.3 5.2e-40 137.7 13.3 2.3 2 1 0 2 2 2 1 ZIP Zinc transporter CDP-OH_P_transf PF01066.21 KFX89608.1 - 1.3e-15 57.9 0.0 1.3e-15 57.9 0.0 2.9 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase Ten_N PF06484.12 KFX89609.1 - 0.075 12.9 0.2 0.075 12.9 0.2 1.5 2 0 0 2 2 2 0 Teneurin Intracellular Region KIX_2 PF16987.5 KFX89610.1 - 8.5e-11 41.7 0.3 3.5e-10 39.7 0.0 2.2 2 0 0 2 2 2 1 KIX domain BBS1 PF14779.6 KFX89610.1 - 0.089 12.2 0.7 0.15 11.5 0.7 1.3 1 0 0 1 1 1 0 Ciliary BBSome complex subunit 1 Peptidase_S21 PF00716.17 KFX89610.1 - 1.4 8.5 10.0 2.1 7.9 10.0 1.2 1 0 0 1 1 1 0 Assemblin (Peptidase family S21) DUF4230 PF14014.6 KFX89610.1 - 1.8 8.8 7.3 1.2 9.4 2.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF4230) LIM PF00412.22 KFX89616.1 - 7.8e-27 93.3 23.0 1.7e-10 40.9 2.7 3.6 4 0 0 4 4 4 3 LIM domain DUF2321 PF10083.9 KFX89616.1 - 0.001 18.7 0.3 0.001 18.7 0.3 3.1 2 1 1 3 3 3 1 Uncharacterized protein conserved in bacteria (DUF2321) DUF3725 PF12523.8 KFX89616.1 - 0.25 11.7 10.8 0.41 11.0 0.1 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3725) zf-SNAP50_C PF12251.8 KFX89616.1 - 4.2 7.0 9.6 12 5.5 0.2 3.1 3 0 0 3 3 3 0 snRNA-activating protein of 50kDa MW C terminal DUF3328 PF11807.8 KFX89617.1 - 6.5e-47 160.1 0.0 7.4e-47 159.9 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) DUF4148 PF13663.6 KFX89618.1 - 0.18 12.0 0.5 0.32 11.2 0.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4148) Ig_2 PF13895.6 KFX89628.1 - 0.039 14.3 0.1 1.2 9.5 0.0 2.3 2 0 0 2 2 2 0 Immunoglobulin domain PLA2_inh PF02988.15 KFX89628.1 - 0.15 12.7 0.3 0.5 11.0 0.1 1.9 2 0 0 2 2 2 0 Phospholipase A2 inhibitor PTR2 PF00854.21 KFX89633.1 - 3.9e-47 161.0 0.3 6.8e-47 160.2 0.3 1.4 1 0 0 1 1 1 1 POT family TssN PF17555.2 KFX89633.1 - 0.18 11.2 1.2 0.53 9.6 0.2 2.2 2 0 0 2 2 2 0 Type VI secretion system, TssN BCDHK_Adom3 PF10436.9 KFX89649.1 - 4e-74 247.8 0.0 6.2e-74 247.2 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.26 KFX89649.1 - 7e-13 49.1 0.0 1.7e-12 47.8 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 KFX89649.1 - 0.057 13.2 0.0 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Serine_rich PF08824.10 KFX89649.1 - 0.068 13.2 0.0 0.13 12.2 0.0 1.4 1 0 0 1 1 1 0 Serine rich protein interaction domain BRO1 PF03097.18 KFX89650.1 - 4.6e-121 404.3 0.0 7e-121 403.7 0.0 1.3 1 0 0 1 1 1 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.6 KFX89650.1 - 2e-75 253.8 0.0 4.2e-75 252.8 0.0 1.6 2 0 0 2 2 2 1 ALIX V-shaped domain binding to HIV EMP24_GP25L PF01105.24 KFX89653.1 - 5.3e-51 173.1 0.0 6.1e-51 173.0 0.0 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD CTP_transf_like PF01467.26 KFX89658.1 - 1.2e-11 45.0 0.0 2.2e-07 31.2 0.0 3.8 2 1 1 4 4 4 2 Cytidylyltransferase-like Oxysterol_BP PF01237.18 KFX89658.1 - 1.5 7.6 6.1 2.3 7.0 6.1 1.2 1 0 0 1 1 1 0 Oxysterol-binding protein WD40 PF00400.32 KFX89664.1 - 1.9e-47 158.3 20.1 3.2e-08 34.1 0.7 8.2 8 0 0 8 8 8 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFX89664.1 - 1e-09 38.6 0.3 0.0016 18.7 0.0 4.3 2 1 3 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KFX89664.1 - 4.9e-08 32.1 0.0 0.0029 16.3 0.0 3.4 3 0 0 3 3 3 2 Nucleoporin Nup120/160 Nucleoporin_N PF08801.11 KFX89664.1 - 0.0022 16.8 0.1 1.1 8.0 0.0 2.6 1 1 1 2 2 2 2 Nup133 N terminal like HECW_N PF16562.5 KFX89664.1 - 0.14 11.9 0.0 0.37 10.6 0.0 1.6 1 0 0 1 1 1 0 N-terminal domain of E3 ubiquitin-protein ligase HECW1 and 2 Pox_A_type_inc PF04508.12 KFX89664.1 - 0.16 11.8 0.1 0.38 10.7 0.1 1.6 1 0 0 1 1 1 0 Viral A-type inclusion protein repeat Na_Ca_ex PF01699.24 KFX89665.1 - 3.5e-45 153.7 41.1 8.8e-25 87.4 17.5 2.2 2 0 0 2 2 2 2 Sodium/calcium exchanger protein TFA2_Winged_2 PF18121.1 KFX89666.1 - 6.5e-25 86.6 0.1 6.9e-24 83.3 0.1 2.3 2 0 0 2 2 2 1 TFA2 Winged helix domain 2 TFIIE_beta PF02186.15 KFX89666.1 - 3.6e-19 68.8 0.1 1.6e-18 66.7 0.1 2.1 2 0 0 2 2 2 1 TFIIE beta subunit core domain LEA_3 PF03242.13 KFX89666.1 - 0.076 13.7 3.5 0.81 10.5 1.2 2.9 3 0 0 3 3 3 0 Late embryogenesis abundant protein DUF1771 PF08590.10 KFX89666.1 - 0.081 13.3 0.5 0.18 12.2 0.5 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1771) TPR_MLP1_2 PF07926.12 KFX89667.1 - 3.1e-37 127.5 23.4 3.1e-37 127.5 23.4 19.6 7 5 9 17 17 17 3 TPR/MLP1/MLP2-like protein LPP PF04728.13 KFX89667.1 - 0.0035 17.7 4.7 0.0035 17.7 4.7 17.9 18 4 2 21 21 21 1 Lipoprotein leucine-zipper HALZ PF02183.18 KFX89667.1 - 0.021 15.0 0.5 0.021 15.0 0.5 14.6 14 1 1 15 15 15 0 Homeobox associated leucine zipper Hexapep PF00132.24 KFX89668.1 - 6.7e-11 41.5 7.6 5.5e-07 29.1 0.6 4.2 3 1 1 4 4 4 2 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 KFX89668.1 - 0.00026 20.7 10.6 0.16 11.7 0.3 4.0 2 2 0 2 2 2 2 Hexapeptide repeat of succinyl-transferase DUF4954 PF16314.5 KFX89668.1 - 0.1 10.7 0.3 0.16 10.1 0.3 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4954) Complex1_51K PF01512.17 KFX89669.1 - 2.4e-46 157.4 0.0 4.1e-46 156.6 0.0 1.4 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase 51 Kd subunit NADH_4Fe-4S PF10589.9 KFX89669.1 - 2.5e-29 101.2 1.4 3.1e-29 100.9 0.2 1.8 2 0 0 2 2 2 1 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region SLBB PF10531.9 KFX89669.1 - 4.3e-09 36.1 0.0 9.4e-09 35.0 0.0 1.6 1 0 0 1 1 1 1 SLBB domain Complex1_LYR_2 PF13233.6 KFX89670.1 - 7.1e-23 81.2 0.7 8.4e-23 80.9 0.7 1.1 1 0 0 1 1 1 1 Complex1_LYR-like Phe_ZIP PF08916.11 KFX89670.1 - 0.027 15.2 0.6 0.26 12.0 0.2 2.1 2 0 0 2 2 2 0 Phenylalanine zipper MMR_HSR1 PF01926.23 KFX89671.1 - 9e-20 70.9 0.0 1.4e-19 70.2 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 KFX89671.1 - 1.5e-06 27.9 0.0 1.5e-05 24.7 0.0 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 KFX89671.1 - 5.4e-05 23.2 0.2 0.0068 16.3 0.1 2.2 2 0 0 2 2 2 1 RsgA GTPase Dynamin_N PF00350.23 KFX89671.1 - 0.00053 20.1 0.1 0.05 13.7 0.5 2.3 1 1 1 2 2 2 1 Dynamin family FeoB_N PF02421.18 KFX89671.1 - 0.00085 18.9 0.0 0.0011 18.5 0.0 1.3 1 0 0 1 1 1 1 Ferrous iron transport protein B SRPRB PF09439.10 KFX89671.1 - 0.0093 15.4 0.0 0.013 15.0 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit IIGP PF05049.13 KFX89671.1 - 0.08 12.0 0.0 0.12 11.4 0.0 1.1 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) AIG1 PF04548.16 KFX89671.1 - 0.13 11.5 0.0 0.18 11.1 0.0 1.3 1 0 0 1 1 1 0 AIG1 family Roc PF08477.13 KFX89671.1 - 0.17 12.1 0.0 0.32 11.2 0.0 1.5 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase Septin PF00735.18 KFX89671.1 - 0.22 10.8 0.0 0.35 10.1 0.0 1.3 1 0 0 1 1 1 0 Septin Sec39 PF08314.11 KFX89686.1 - 5e-189 630.4 0.0 5.7e-189 630.2 0.0 1.0 1 0 0 1 1 1 1 Secretory pathway protein Sec39 Ndufs5 PF10200.9 KFX89687.1 - 8.7e-05 22.7 0.0 0.00011 22.4 0.0 1.1 1 0 0 1 1 1 1 NADH:ubiquinone oxidoreductase, NDUFS5-15kDa DUF3128 PF11326.8 KFX89687.1 - 0.0011 19.2 0.6 0.0024 18.2 0.6 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF3128) COX17 PF05051.13 KFX89687.1 - 0.045 14.1 0.3 0.073 13.4 0.3 1.4 1 0 0 1 1 1 0 Cytochrome C oxidase copper chaperone (COX17) UPF0203 PF05254.12 KFX89687.1 - 0.24 11.7 2.1 0.4 11.0 2.1 1.4 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0203) FAM176 PF14851.6 KFX89688.1 - 0.13 12.0 0.6 0.31 10.7 0.6 1.6 1 0 0 1 1 1 0 FAM176 family NOA36 PF06524.12 KFX89688.1 - 0.29 10.4 4.0 0.55 9.5 4.0 1.4 1 0 0 1 1 1 0 NOA36 protein PBP1_TM PF14812.6 KFX89688.1 - 2.8 8.4 7.7 8.2 6.9 7.7 1.8 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal GST_N PF02798.20 KFX89689.1 - 1.4e-13 51.0 0.0 2.3e-13 50.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 KFX89689.1 - 2.2e-13 50.2 0.0 4.8e-13 49.1 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 KFX89689.1 - 6.1e-13 49.0 0.0 1.1e-12 48.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 KFX89689.1 - 7.3e-12 45.3 0.0 1.8e-11 44.1 0.0 1.8 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 KFX89689.1 - 1.8e-10 40.9 0.0 3.9e-10 39.9 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KFX89689.1 - 1.2e-06 28.4 0.0 2.6e-06 27.3 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain zf-RING_5 PF14634.6 KFX89693.1 - 6.6e-05 22.8 0.6 0.0005 20.0 0.1 2.2 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 KFX89693.1 - 0.00074 19.5 2.0 0.0026 17.7 2.0 1.9 1 1 0 1 1 1 1 RING-type zinc-finger Prok-RING_4 PF14447.6 KFX89693.1 - 0.0032 17.3 1.2 0.022 14.6 0.2 2.3 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-C3HC4 PF00097.25 KFX89693.1 - 0.0077 16.1 1.0 0.016 15.1 0.1 1.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KFX89693.1 - 0.018 14.9 0.3 0.018 14.9 0.3 1.8 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) FYVE PF01363.21 KFX89693.1 - 0.024 14.8 1.2 0.25 11.5 1.1 2.1 2 0 0 2 2 2 0 FYVE zinc finger zf-C3HC4_3 PF13920.6 KFX89693.1 - 0.024 14.5 1.4 0.087 12.7 0.2 2.1 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 KFX89693.1 - 0.05 13.8 1.6 0.1 12.8 0.2 2.0 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.6 KFX89693.1 - 0.052 13.9 1.8 0.21 12.0 0.3 2.2 2 0 0 2 2 2 0 Ring finger domain Prok-RING_1 PF14446.6 KFX89693.1 - 0.56 10.2 6.5 0.82 9.6 0.5 2.3 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 Cullin_binding PF03556.15 KFX89694.1 - 3.9e-31 108.0 8.4 6.1e-31 107.4 8.4 1.3 1 0 0 1 1 1 1 Cullin binding Ank_2 PF12796.7 KFX89694.1 - 2.1e-06 28.2 0.0 4e-06 27.3 0.0 1.4 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) UBA_4 PF14555.6 KFX89694.1 - 4.3e-06 26.5 0.0 8e-06 25.6 0.0 1.5 1 0 0 1 1 1 1 UBA-like domain Ank_4 PF13637.6 KFX89694.1 - 0.0025 18.4 0.0 0.0058 17.2 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFX89694.1 - 0.0072 16.7 0.0 0.028 14.9 0.0 2.0 2 0 0 2 2 2 1 Ankyrin repeat Ank PF00023.30 KFX89694.1 - 0.019 15.4 0.0 0.089 13.3 0.0 2.1 2 0 0 2 2 2 0 Ankyrin repeat Ank_5 PF13857.6 KFX89694.1 - 0.032 14.6 0.0 0.083 13.2 0.0 1.7 1 0 0 1 1 1 0 Ankyrin repeats (many copies) Ribosomal_S6 PF01250.17 KFX89695.1 - 2.7e-23 82.0 0.0 3.2e-23 81.8 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S6 Amidohydro_1 PF01979.20 KFX89696.1 - 5.4e-17 62.1 0.1 9.9e-17 61.3 0.1 1.3 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 KFX89696.1 - 7.3e-09 35.6 1.2 8.9e-09 35.3 0.1 1.7 2 0 0 2 2 2 1 Amidohydrolase family SARAF PF06682.12 KFX89710.1 - 0.0003 20.5 0.4 0.00055 19.7 0.4 1.4 1 0 0 1 1 1 1 SOCE-associated regulatory factor of calcium homoeostasis DUF4690 PF15756.5 KFX89710.1 - 0.00045 20.8 0.3 0.0017 18.9 0.3 2.0 1 0 0 1 1 1 1 Small Novel Rich in Cartilage SH3_9 PF14604.6 KFX89710.1 - 0.0016 18.3 0.1 0.0035 17.2 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KFX89710.1 - 0.0043 16.6 0.2 0.0086 15.7 0.2 1.5 1 0 0 1 1 1 1 SH3 domain Bacteriocin_IIc PF10439.9 KFX89710.1 - 0.012 15.7 9.3 0.053 13.6 1.1 2.8 2 0 0 2 2 2 0 Bacteriocin class II with double-glycine leader peptide DAP10 PF07213.11 KFX89710.1 - 0.03 14.3 0.8 0.18 11.8 0.1 2.5 2 0 0 2 2 2 0 DAP10 membrane protein DUF2613 PF11021.8 KFX89710.1 - 0.042 14.0 0.7 0.042 14.0 0.7 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF2613) Syndecan PF01034.20 KFX89710.1 - 0.044 13.7 2.3 0.096 12.6 2.3 1.5 1 0 0 1 1 1 0 Syndecan domain Podoplanin PF05808.11 KFX89710.1 - 0.046 13.8 0.2 0.095 12.8 0.2 1.5 1 0 0 1 1 1 0 Podoplanin Gly-zipper_YMGG PF13441.6 KFX89710.1 - 3.8 7.3 16.9 4.8 7.0 4.5 2.4 2 0 0 2 2 2 0 YMGG-like Gly-zipper HAD PF12710.7 KFX89716.1 - 5.5e-23 82.3 0.0 8.6e-23 81.7 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Put_Phosphatase PF06888.12 KFX89716.1 - 9.7e-05 21.9 0.0 0.074 12.4 0.0 2.1 2 0 0 2 2 2 2 Putative Phosphatase Hydrolase PF00702.26 KFX89716.1 - 0.003 17.9 0.1 0.25 11.6 0.0 3.0 1 1 1 2 2 2 1 haloacid dehalogenase-like hydrolase UMPH-1 PF05822.12 KFX89716.1 - 0.031 13.8 0.0 0.051 13.1 0.0 1.4 1 0 0 1 1 1 0 Pyrimidine 5'-nucleotidase (UMPH-1) Solute_trans_a PF03619.16 KFX89728.1 - 3.3e-58 197.3 12.6 4.3e-58 196.9 12.6 1.1 1 0 0 1 1 1 1 Organic solute transporter Ostalpha Sulf_transp PF04143.14 KFX89728.1 - 0.021 14.4 2.4 0.26 10.8 0.1 2.3 2 0 0 2 2 2 0 Sulphur transport PS_Dcarbxylase PF02666.15 KFX89729.1 - 2.8e-52 177.2 0.0 3.1e-52 177.1 0.0 1.0 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase AMP-binding PF00501.28 KFX89730.1 - 3.2e-216 717.8 0.0 8.7e-75 251.9 0.0 3.3 3 0 0 3 3 3 3 AMP-binding enzyme Condensation PF00668.20 KFX89730.1 - 3.5e-156 520.5 0.0 8.5e-43 146.7 0.0 4.3 4 0 0 4 4 4 4 Condensation domain PP-binding PF00550.25 KFX89730.1 - 5.1e-34 116.5 0.5 2.8e-12 46.8 0.0 3.9 3 0 0 3 3 3 3 Phosphopantetheine attachment site AMP-binding_C PF13193.6 KFX89730.1 - 2.1e-06 28.6 0.0 2.3 9.2 0.0 4.0 3 0 0 3 3 3 3 AMP-binding enzyme C-terminal domain Tri3 PF07428.11 KFX89731.1 - 4e-17 62.2 0.1 1.2e-16 60.7 0.1 1.6 1 1 0 1 1 1 1 15-O-acetyltransferase Tri3 CWC25 PF12542.8 KFX89732.1 - 1.9e-25 89.7 1.8 1.9e-25 89.7 1.8 3.4 3 1 1 4 4 4 1 Pre-mRNA splicing factor Cir_N PF10197.9 KFX89732.1 - 2.2e-13 50.1 8.9 2.2e-13 50.1 8.9 4.3 4 0 0 4 4 4 1 N-terminal domain of CBF1 interacting co-repressor CIR SelP_N PF04592.14 KFX89732.1 - 7.9 5.8 10.5 19 4.5 10.5 1.7 1 0 0 1 1 1 0 Selenoprotein P, N terminal region PCI PF01399.27 KFX89733.1 - 3.5e-19 69.2 1.5 8.6e-19 68.0 0.1 2.3 2 1 0 2 2 2 1 PCI domain TPR_7 PF13176.6 KFX89733.1 - 0.043 13.9 0.3 9.9 6.5 0.0 3.7 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.17 KFX89733.1 - 0.051 13.7 1.7 0.79 10.0 0.0 3.6 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_11 PF13414.6 KFX89733.1 - 0.13 12.0 0.5 0.49 10.1 0.1 2.3 2 0 0 2 2 2 0 TPR repeat TPR_1 PF00515.28 KFX89733.1 - 0.15 11.9 0.3 1.6 8.7 0.1 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat CN_hydrolase PF00795.22 KFX89736.1 - 2.4e-60 204.1 0.0 2.7e-60 203.9 0.0 1.0 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Cyto_heme_lyase PF01265.17 KFX89739.1 - 4.2e-43 148.0 2.4 2.7e-41 142.1 2.3 2.6 1 1 0 1 1 1 1 Cytochrome c/c1 heme lyase tRNA-synt_1g PF09334.11 KFX89740.1 - 7.1e-145 482.6 0.2 1.5e-144 481.5 0.1 1.5 2 0 0 2 2 2 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.22 KFX89740.1 - 7.8e-05 21.1 0.2 0.26 9.5 0.0 3.2 1 1 1 2 2 2 2 tRNA synthetases class I (I, L, M and V) Laminin_EGF PF00053.24 KFX89740.1 - 0.11 12.7 1.8 0.23 11.7 1.8 1.5 1 0 0 1 1 1 0 Laminin EGF domain Yae1_N PF09811.9 KFX89741.1 - 3.6e-10 39.4 4.8 5.5e-10 38.8 4.8 1.3 1 0 0 1 1 1 1 Essential protein Yae1, N terminal S36_mt PF10937.8 KFX89742.1 - 5.7e-40 137.5 0.7 6.8e-40 137.3 0.7 1.1 1 0 0 1 1 1 1 Ribosomal protein S36, mitochondrial Med18 PF09637.10 KFX89743.1 - 7.4e-26 91.5 0.0 8.4e-26 91.3 0.0 1.0 1 0 0 1 1 1 1 Med18 protein PNK3P PF08645.11 KFX89744.1 - 7.4e-52 175.3 0.0 1.1e-51 174.7 0.0 1.3 1 0 0 1 1 1 1 Polynucleotide kinase 3 phosphatase AAA_33 PF13671.6 KFX89744.1 - 9.2e-15 55.0 0.1 3.2e-06 27.4 0.0 3.0 2 1 1 3 3 3 2 AAA domain eIF3m_C_helix PF18005.1 KFX89744.1 - 0.043 13.5 0.4 0.073 12.8 0.4 1.4 1 0 0 1 1 1 0 eIF3 subunit M, C-terminal helix DUF2390 PF09523.10 KFX89744.1 - 0.078 13.3 0.0 0.35 11.2 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2390) PROL5-SMR PF15621.6 KFX89744.1 - 8.6 6.9 7.2 31 5.1 7.2 2.0 1 0 0 1 1 1 0 Proline-rich submaxillary gland androgen-regulated family Peptidase_M48_N PF16491.5 KFX89748.1 - 1.4e-66 223.9 11.1 1.4e-66 223.9 11.1 1.9 2 0 0 2 2 2 1 CAAX prenyl protease N-terminal, five membrane helices Peptidase_M48 PF01435.18 KFX89748.1 - 9.2e-45 152.8 0.0 1.8e-44 151.8 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M48 Peptidase_M56 PF05569.11 KFX89748.1 - 0.00052 19.3 0.1 0.001 18.4 0.1 1.4 1 0 0 1 1 1 1 BlaR1 peptidase M56 DUF4538 PF15061.6 KFX89748.1 - 0.2 11.4 0.6 0.51 10.1 0.6 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4538) PRODH PF18327.1 KFX89749.1 - 0.25 11.6 1.1 4.3 7.6 0.2 2.7 3 0 0 3 3 3 0 Proline utilization A proline dehydrogenase N-terminal domain GHMP_kinases_N PF00288.26 KFX89750.1 - 4e-15 55.8 0.1 1.1e-14 54.4 0.1 1.8 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 KFX89750.1 - 8.7e-09 35.6 0.0 2.4e-08 34.2 0.0 1.7 1 0 0 1 1 1 1 GHMP kinases C terminal GalKase_gal_bdg PF10509.9 KFX89750.1 - 0.0019 17.7 0.0 0.0055 16.2 0.0 1.8 1 0 0 1 1 1 1 Galactokinase galactose-binding signature PPTA PF01239.22 KFX89751.1 - 2.8e-38 128.6 14.7 1.9e-07 30.6 0.2 5.7 5 0 0 5 5 5 5 Protein prenyltransferase alpha subunit repeat COesterase PF00135.28 KFX89755.1 - 2.1e-24 86.3 0.1 3.5e-24 85.5 0.1 1.3 1 0 0 1 1 1 1 Carboxylesterase family Sterol_MT_C PF08498.10 KFX89755.1 - 3.1e-16 59.4 0.3 6.3e-16 58.4 0.3 1.5 1 0 0 1 1 1 1 Sterol methyltransferase C-terminal CMAS PF02353.20 KFX89755.1 - 8.6e-16 58.0 0.0 1.3e-15 57.5 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_11 PF08241.12 KFX89755.1 - 1.5e-15 57.6 0.0 2.7e-15 56.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KFX89755.1 - 8.5e-15 55.3 0.0 1.6e-14 54.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KFX89755.1 - 8e-11 42.0 0.0 1.2e-10 41.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KFX89755.1 - 1.3e-09 38.6 0.1 4.9e-09 36.8 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 KFX89755.1 - 6.6e-09 35.8 0.0 1.2e-08 34.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KFX89755.1 - 1.6e-07 30.9 0.0 2.9e-07 30.1 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.14 KFX89755.1 - 0.00015 21.4 0.0 0.00024 20.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Abhydrolase_3 PF07859.13 KFX89755.1 - 0.001 18.9 0.0 0.0043 16.9 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold PCMT PF01135.19 KFX89755.1 - 0.0016 18.2 0.1 0.0025 17.6 0.1 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_15 PF09445.10 KFX89755.1 - 0.054 13.1 0.0 0.081 12.5 0.0 1.3 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase Methyltransf_2 PF00891.18 KFX89755.1 - 0.065 12.5 0.1 0.12 11.7 0.1 1.3 1 0 0 1 1 1 0 O-methyltransferase domain FtsJ PF01728.19 KFX89755.1 - 0.12 12.5 0.0 0.21 11.7 0.0 1.4 1 0 0 1 1 1 0 FtsJ-like methyltransferase DOT1 PF08123.13 KFX89755.1 - 0.13 11.8 0.0 0.23 10.9 0.0 1.4 1 0 0 1 1 1 0 Histone methylation protein DOT1 p450 PF00067.22 KFX89756.1 - 2.2e-24 86.0 0.0 2.9e-24 85.7 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 Phage_lysozyme PF00959.19 KFX89758.1 - 2.8e-12 47.1 0.0 4.6e-12 46.4 0.0 1.4 1 0 0 1 1 1 1 Phage lysozyme SH3_3 PF08239.11 KFX89758.1 - 1.6e-05 25.1 0.3 0.00027 21.1 0.2 2.4 2 0 0 2 2 2 1 Bacterial SH3 domain CHAP PF05257.16 KFX89759.1 - 4.8e-13 49.5 4.8 4.8e-13 49.5 4.8 2.0 2 0 0 2 2 2 1 CHAP domain SH3_3 PF08239.11 KFX89759.1 - 0.00011 22.5 1.3 0.00018 21.7 0.1 2.0 2 0 0 2 2 2 1 Bacterial SH3 domain Porin_OmpG_1_2 PF16946.5 KFX89759.1 - 0.024 13.9 0.1 0.043 13.1 0.1 1.3 1 0 0 1 1 1 0 OMPG-porin 1 family zf-C2H2 PF00096.26 KFX89773.1 - 0.0012 19.1 13.8 0.69 10.5 1.7 3.8 3 0 0 3 3 3 3 Zinc finger, C2H2 type RSN1_7TM PF02714.15 KFX89784.1 - 7.7e-89 297.6 26.0 5.2e-88 294.9 24.1 2.3 2 0 0 2 2 2 1 Calcium-dependent channel, 7TM region, putative phosphate RSN1_TM PF13967.6 KFX89784.1 - 2.8e-44 150.6 1.1 2.8e-44 150.6 1.1 3.0 4 0 0 4 4 4 1 Late exocytosis, associated with Golgi transport PHM7_cyt PF14703.6 KFX89784.1 - 2.4e-38 132.1 0.0 3.7e-38 131.5 0.0 1.3 1 0 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter PHM7_ext PF12621.8 KFX89784.1 - 6.4e-35 119.2 0.1 2.7e-33 114.0 0.0 2.3 2 0 0 2 2 2 1 Extracellular tail, of 10TM putative phosphate transporter ODV-E18 PF10717.9 KFX89784.1 - 1.5 8.8 4.2 20 5.1 1.0 2.9 2 0 0 2 2 2 0 Occlusion-derived virus envelope protein ODV-E18 Ank_2 PF12796.7 KFX89789.1 - 1.2e-55 186.0 15.8 8.5e-12 45.5 0.0 6.4 2 2 6 8 8 8 8 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KFX89789.1 - 2.6e-46 155.4 13.5 2.2e-09 37.7 0.0 10.2 4 2 7 11 11 11 11 Ankyrin repeats (many copies) Ank PF00023.30 KFX89789.1 - 1.7e-44 148.4 16.8 0.00019 21.7 0.0 12.2 12 0 0 12 12 12 11 Ankyrin repeat Ank_3 PF13606.6 KFX89789.1 - 6.7e-35 115.2 9.7 0.0022 18.3 0.0 12.0 12 1 0 12 12 12 8 Ankyrin repeat Ank_5 PF13857.6 KFX89789.1 - 9e-34 115.1 15.8 9e-05 22.7 0.0 8.0 5 3 2 7 7 7 7 Ankyrin repeats (many copies) Ank_2 PF12796.7 KFX89790.1 - 2.7e-68 226.6 2.4 2.7e-17 63.1 1.9 5.8 1 1 4 6 6 6 6 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KFX89790.1 - 2.6e-55 177.9 1.8 0.00033 20.8 0.0 12.0 12 0 0 12 12 12 9 Ankyrin repeat Ank_4 PF13637.6 KFX89790.1 - 2.3e-49 165.2 2.3 9.1e-09 35.7 0.1 9.2 5 2 4 9 9 9 8 Ankyrin repeats (many copies) Ank PF00023.30 KFX89790.1 - 3.3e-49 163.3 6.8 0.00011 22.5 0.0 12.0 12 0 0 12 12 12 9 Ankyrin repeat Ank_5 PF13857.6 KFX89790.1 - 2.4e-44 148.8 7.1 4.4e-07 30.0 0.1 9.3 3 3 6 9 9 9 9 Ankyrin repeats (many copies) PEGA PF08308.11 KFX89790.1 - 0.1 12.5 0.0 2 8.4 0.0 3.2 2 1 0 2 2 2 0 PEGA domain VWA_3_C PF18571.1 KFX89790.1 - 0.2 11.6 3.2 9.4 6.2 0.0 4.6 5 0 0 5 5 5 0 von Willebrand factor type A C-terminal domain Shigella_OspC PF06128.11 KFX89790.1 - 0.85 9.3 2.7 2e+02 1.5 0.0 4.7 3 1 2 6 6 6 0 Shigella flexneri OspC protein NDUFA12 PF05071.16 KFX89792.1 - 4.5e-05 24.2 0.0 6e-05 23.8 0.0 1.2 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase subunit NDUFA12 PLDc_2 PF13091.6 KFX89793.1 - 3.6e-15 56.0 0.0 4.1e-06 26.7 0.0 2.6 2 1 0 2 2 2 2 PLD-like domain PLDc PF00614.22 KFX89793.1 - 6.1e-08 32.5 0.1 0.00018 21.5 0.0 2.6 2 0 0 2 2 2 2 Phospholipase D Active site motif Glyco_hydro_35 PF01301.19 KFX89795.1 - 1.7e-75 254.6 1.7 2.6e-75 254.0 1.7 1.3 1 1 0 1 1 1 1 Glycosyl hydrolases family 35 Cellulase PF00150.18 KFX89795.1 - 0.00021 20.8 0.4 0.00037 20.0 0.4 1.3 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) AP_endonuc_2 PF01261.24 KFX89795.1 - 0.1 12.0 0.0 0.15 11.5 0.0 1.3 1 0 0 1 1 1 0 Xylose isomerase-like TIM barrel Glyco_hydro_49N PF17433.2 KFX89796.1 - 9.1e-62 208.0 1.2 2.1e-61 206.9 1.2 1.6 1 0 0 1 1 1 1 Glycosyl hydrolase family 49 N-terminal Ig-like domain Glyco_hydro_49 PF03718.13 KFX89796.1 - 2.8e-26 91.8 1.1 7.8e-26 90.4 0.3 2.1 2 0 0 2 2 2 1 Glycosyl hydrolase family 49 IPU_b_solenoid PF18783.1 KFX89796.1 - 4.4e-23 81.0 1.5 1.2e-22 79.6 1.5 1.8 1 0 0 1 1 1 1 Isopullulanase beta-solenoid repeat B_solenoid_dext PF18841.1 KFX89796.1 - 1.8e-15 56.9 1.3 9.5e-15 54.6 1.4 2.3 2 0 0 2 2 2 1 Beta solenoid repeat from Dextranase Glyco_hydro_28 PF00295.17 KFX89796.1 - 0.00063 18.9 0.0 0.0011 18.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 Alpha-amylase PF00128.24 KFX89797.1 - 5.6e-112 374.6 0.0 9.2e-112 373.9 0.0 1.3 1 0 0 1 1 1 1 Alpha amylase, catalytic domain Malt_amylase_C PF16657.5 KFX89797.1 - 2.6e-06 27.5 0.0 5e-06 26.5 0.0 1.5 1 0 0 1 1 1 1 Maltogenic Amylase, C-terminal domain hDGE_amylase PF14701.6 KFX89797.1 - 0.017 14.2 0.1 0.066 12.3 0.0 1.8 2 0 0 2 2 2 0 Glycogen debranching enzyme, glucanotransferase domain DUF3459 PF11941.8 KFX89797.1 - 0.074 13.4 0.0 0.18 12.2 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3459) Sugar_tr PF00083.24 KFX89798.1 - 1.2e-88 298.0 22.5 1.4e-88 297.8 22.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KFX89798.1 - 3.3e-17 62.5 35.5 5.7e-12 45.2 14.9 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 KFX89798.1 - 5.4e-06 25.2 2.4 5.4e-06 25.2 2.4 2.8 3 0 0 3 3 3 2 MFS/sugar transport protein MFS_1_like PF12832.7 KFX89798.1 - 0.0013 17.7 3.0 0.0013 17.7 3.0 1.8 2 0 0 2 2 2 1 MFS_1 like family Fungal_trans PF04082.18 KFX89799.1 - 1.5e-06 27.5 4.9 2.3e-06 26.9 4.9 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF2713 PF10897.8 KFX89799.1 - 0.028 14.1 0.2 6.5 6.3 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2713) AadA_C PF18280.1 KFX89799.1 - 0.062 13.4 0.1 2.4 8.3 0.0 2.3 2 0 0 2 2 2 0 Aminoglycoside adenyltransferase C-terminal domain ATP-synt_C PF00137.21 KFX89800.1 - 1.7e-07 31.5 12.7 4.3e-07 30.2 12.7 1.7 1 0 0 1 1 1 1 ATP synthase subunit C CAP59_mtransfer PF11735.8 KFX89801.1 - 5.5e-86 288.2 0.0 8.7e-86 287.5 0.0 1.3 1 0 0 1 1 1 1 Cryptococcal mannosyltransferase 1 APH PF01636.23 KFX89801.1 - 2.1e-15 57.3 0.0 1.7e-14 54.4 0.0 2.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KFX89801.1 - 0.008 15.8 0.0 0.021 14.4 0.0 1.6 1 1 0 1 1 1 1 Choline/ethanolamine kinase RSN1_7TM PF02714.15 KFX89803.1 - 5.6e-79 265.3 18.3 9.6e-79 264.5 18.3 1.4 1 0 0 1 1 1 1 Calcium-dependent channel, 7TM region, putative phosphate PHM7_cyt PF14703.6 KFX89803.1 - 2.1e-39 135.5 0.0 3e-39 135.0 0.0 1.2 1 0 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter RSN1_TM PF13967.6 KFX89803.1 - 2e-36 125.1 0.2 5.3e-36 123.7 0.2 1.8 1 0 0 1 1 1 1 Late exocytosis, associated with Golgi transport SGL PF08450.12 KFX89804.1 - 2.8e-64 217.1 0.1 4e-64 216.6 0.1 1.2 1 0 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region Reg_prop PF07494.11 KFX89804.1 - 0.069 13.4 0.1 2.1 8.8 0.0 3.0 2 0 0 2 2 2 0 Two component regulator propeller Clr5 PF14420.6 KFX89805.1 - 2.9e-09 37.0 0.2 5.2e-09 36.2 0.2 1.5 1 0 0 1 1 1 1 Clr5 domain Myb_DNA-bind_2 PF08914.11 KFX89805.1 - 0.0023 18.1 1.5 0.0054 16.9 1.5 1.6 1 0 0 1 1 1 1 Rap1 Myb domain Fungal_trans PF04082.18 KFX89806.1 - 4e-15 55.6 0.4 7.1e-15 54.7 0.4 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KFX89806.1 - 1.1e-07 31.8 9.6 2e-07 31.0 9.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain NmrA PF05368.13 KFX89807.1 - 1.1e-23 84.0 0.0 1.4e-23 83.7 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KFX89807.1 - 1.1e-14 54.7 0.2 6.2e-14 52.3 0.2 2.0 1 1 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KFX89807.1 - 0.00071 19.1 0.6 0.0018 17.8 0.2 1.8 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family Semialdhyde_dh PF01118.24 KFX89807.1 - 0.065 13.7 0.2 0.16 12.4 0.1 1.8 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain RmlD_sub_bind PF04321.17 KFX89807.1 - 0.14 11.2 0.2 1.9 7.5 0.1 2.1 2 0 0 2 2 2 0 RmlD substrate binding domain Ldh_1_N PF00056.23 KFX89807.1 - 0.14 12.2 0.1 0.3 11.2 0.1 1.5 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain Shikimate_DH PF01488.20 KFX89807.1 - 0.15 12.1 0.0 0.29 11.2 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase DapB_N PF01113.20 KFX89807.1 - 0.16 12.1 0.8 0.23 11.6 0.1 1.7 2 0 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus zf-RING_2 PF13639.6 KFX89808.1 - 2.7e-14 53.2 5.5 2.7e-14 53.2 5.5 2.5 2 1 0 2 2 1 1 Ring finger domain zf-RING_11 PF17123.5 KFX89808.1 - 7.8e-11 41.5 1.8 7.8e-11 41.5 1.8 2.1 2 0 0 2 2 2 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 KFX89808.1 - 7.2e-10 38.5 3.9 7.2e-10 38.5 3.9 2.7 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KFX89808.1 - 1.1e-07 31.6 3.1 1.1e-07 31.6 3.1 2.2 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KFX89808.1 - 1.8e-07 30.9 2.3 1.8e-07 30.9 2.3 2.4 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 KFX89808.1 - 2.3e-07 31.0 2.5 2.3e-07 31.0 2.5 2.3 2 0 0 2 2 2 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 KFX89808.1 - 2.4e-07 30.6 3.5 2.4e-07 30.6 3.5 2.7 2 1 0 2 2 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 KFX89808.1 - 1.5e-06 28.1 2.9 2.1e-05 24.4 0.5 2.6 2 0 0 2 2 2 1 RING-type zinc-finger Prok-RING_4 PF14447.6 KFX89808.1 - 2.5e-06 27.2 3.2 2.5e-06 27.2 3.2 2.0 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-ANAPC11 PF12861.7 KFX89808.1 - 0.00021 21.3 1.0 0.00021 21.3 1.0 2.4 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger Vps39_2 PF10367.9 KFX89808.1 - 0.0035 17.8 0.9 0.015 15.7 0.1 2.2 2 0 0 2 2 2 1 Vacuolar sorting protein 39 domain 2 zf-RING_4 PF14570.6 KFX89808.1 - 0.019 14.8 5.5 0.019 14.8 5.5 2.4 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain Prok-RING_1 PF14446.6 KFX89808.1 - 0.049 13.6 0.7 0.049 13.6 0.7 3.3 3 0 0 3 3 3 0 Prokaryotic RING finger family 1 Integrin_alpha2 PF08441.12 KFX89809.1 - 0.058 12.3 0.1 0.063 12.1 0.1 1.0 1 0 0 1 1 1 0 Integrin alpha PRP38 PF03371.15 KFX89822.1 - 1.3e-55 188.0 0.0 1.5e-55 187.7 0.0 1.1 1 0 0 1 1 1 1 PRP38 family Ank_4 PF13637.6 KFX89823.1 - 6.2e-47 157.4 5.1 7.7e-11 42.3 0.1 5.8 1 1 5 6 6 6 5 Ankyrin repeats (many copies) Ank_2 PF12796.7 KFX89823.1 - 7.6e-43 145.0 0.7 2.7e-13 50.3 0.1 3.6 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.30 KFX89823.1 - 1.2e-36 123.6 1.3 3.4e-07 30.4 0.0 7.0 6 0 0 6 6 6 6 Ankyrin repeat Ank_5 PF13857.6 KFX89823.1 - 9.5e-36 121.4 8.2 7.1e-12 45.3 0.1 7.3 2 1 6 8 8 8 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFX89823.1 - 1.3e-33 111.2 0.0 5.7e-07 29.4 0.0 7.4 6 2 1 7 7 7 5 Ankyrin repeat Pkinase PF00069.25 KFX89823.1 - 8.8e-29 100.7 0.0 1.3e-28 100.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFX89823.1 - 6.3e-15 55.2 0.0 1.1e-14 54.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_Tyr PF07714.17 KFX89824.1 - 0.014 14.7 0.0 0.33 10.2 0.0 2.1 2 0 0 2 2 2 0 Protein tyrosine kinase Pkinase PF00069.25 KFX89824.1 - 0.017 14.5 0.0 0.17 11.3 0.0 2.0 1 1 0 1 1 1 0 Protein kinase domain DUF3933 PF13069.6 KFX89824.1 - 0.068 13.0 0.0 0.16 11.9 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3933) eIF-5a PF01287.20 KFX89825.1 - 6.9e-06 26.1 0.0 2.2e-05 24.5 0.0 1.8 2 0 0 2 2 2 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold DUF948 PF06103.11 KFX89826.1 - 0.33 11.2 11.6 0.39 11.0 0.7 4.2 2 2 2 4 4 4 0 Bacterial protein of unknown function (DUF948) DUF4336 PF14234.6 KFX89827.1 - 4.1e-17 62.4 0.0 3.8e-11 42.7 0.0 2.9 2 1 0 2 2 2 2 Domain of unknown function (DUF4336) DUF4823 PF16105.5 KFX89832.1 - 0.11 12.3 0.1 0.24 11.3 0.1 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4823) Amidase PF01425.21 KFX89834.1 - 2.2e-84 284.0 0.9 2.8e-84 283.7 0.9 1.0 1 0 0 1 1 1 1 Amidase Lentivirus_VIF PF05851.11 KFX89834.1 - 0.0011 17.9 0.0 0.0016 17.4 0.0 1.1 1 0 0 1 1 1 1 Lentivirus virion infectivity factor (VIF) CVNH PF08881.10 KFX89839.1 - 4.2e-18 65.9 0.0 5.1e-18 65.6 0.0 1.1 1 0 0 1 1 1 1 CVNH domain Bac_rhamnosid6H PF17389.2 KFX89840.1 - 1.3e-06 27.9 0.0 1.5e-05 24.4 0.0 2.2 2 0 0 2 2 2 1 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain DUF2201 PF09967.9 KFX89840.1 - 0.13 12.4 0.1 2.4 8.3 0.0 2.4 2 0 0 2 2 2 0 VWA-like domain (DUF2201) zf-C2HE PF16278.5 KFX89841.1 - 5.7e-18 65.1 0.0 1.2e-17 64.0 0.0 1.6 1 0 0 1 1 1 1 C2HE / C2H2 / C2HC zinc-binding finger DcpS_C PF11969.8 KFX89841.1 - 4.3e-15 56.2 3.9 5.7e-14 52.6 3.0 2.4 2 1 0 2 2 2 1 Scavenger mRNA decapping enzyme C-term binding HIT PF01230.23 KFX89841.1 - 1.6e-13 51.2 0.1 3.9e-13 49.9 0.1 1.6 1 1 0 1 1 1 1 HIT domain AphA_like PF14557.6 KFX89841.1 - 0.12 12.1 0.0 0.2 11.4 0.0 1.3 1 0 0 1 1 1 0 Putative AphA-like transcriptional regulator HA2 PF04408.23 KFX89842.1 - 2.3e-15 56.8 2.2 4.6e-15 55.8 0.0 2.6 3 0 0 3 3 3 1 Helicase associated domain (HA2) Helicase_C PF00271.31 KFX89842.1 - 3.8e-15 56.2 0.9 2.2e-14 53.8 0.1 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain OB_NTP_bind PF07717.16 KFX89842.1 - 5.1e-13 49.2 0.0 1e-12 48.3 0.0 1.5 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold RWD PF05773.22 KFX89842.1 - 1e-11 45.1 0.0 2.2e-11 44.1 0.0 1.6 1 0 0 1 1 1 1 RWD domain DEAD PF00270.29 KFX89842.1 - 5.1e-10 39.4 0.2 1.2e-09 38.2 0.1 1.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase ResIII PF04851.15 KFX89842.1 - 0.00075 19.5 0.0 0.0018 18.3 0.0 1.6 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit dsRBD2 PF17842.1 KFX89842.1 - 0.0028 17.9 0.0 0.0061 16.8 0.0 1.5 1 0 0 1 1 1 1 Double-stranded RNA binding domain 2 AAA_22 PF13401.6 KFX89842.1 - 0.0031 17.8 2.4 0.013 15.7 2.4 2.0 1 1 0 1 1 1 1 AAA domain IHABP4_N PF16174.5 KFX89842.1 - 0.0047 17.6 0.3 0.0047 17.6 0.3 2.1 2 0 0 2 2 1 1 Intracellular hyaluronan-binding protein 4 N-terminal DND1_DSRM PF14709.7 KFX89842.1 - 0.017 15.4 0.1 0.042 14.1 0.1 1.7 1 0 0 1 1 1 0 double strand RNA binding domain from DEAD END PROTEIN 1 AAA_23 PF13476.6 KFX89842.1 - 0.019 15.4 0.1 0.075 13.5 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.6 KFX89842.1 - 0.023 14.4 0.2 0.11 12.3 0.0 2.2 2 0 0 2 2 2 0 P-loop containing region of AAA domain T2SSE PF00437.20 KFX89842.1 - 0.028 13.5 0.0 0.054 12.5 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein ATPase PF06745.13 KFX89842.1 - 0.033 13.5 0.0 0.074 12.4 0.0 1.5 1 0 0 1 1 1 0 KaiC IstB_IS21 PF01695.17 KFX89842.1 - 0.035 13.8 0.1 0.7 9.6 0.1 2.3 2 0 0 2 2 2 0 IstB-like ATP binding protein DUF2533 PF10752.9 KFX89842.1 - 0.12 12.9 0.6 0.33 11.4 0.6 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2533) adh_short PF00106.25 KFX89852.1 - 1.2e-53 181.6 3.2 1.4e-53 181.3 3.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KFX89852.1 - 2.7e-44 151.5 1.3 3.3e-44 151.2 1.3 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KFX89852.1 - 3.2e-17 63.0 1.4 4.3e-17 62.6 1.4 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KFX89852.1 - 5.9e-07 29.2 1.3 1.4e-05 24.7 0.1 2.7 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 KFX89852.1 - 9.1e-06 25.7 3.1 1.9e-05 24.6 3.1 1.5 1 1 0 1 1 1 1 NAD(P)H-binding THF_DHG_CYH_C PF02882.19 KFX89852.1 - 0.00082 18.7 0.7 0.0026 17.1 0.2 1.9 1 1 1 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Polysacc_synt_2 PF02719.15 KFX89852.1 - 0.0013 18.0 0.5 0.002 17.3 0.5 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein DFP PF04127.15 KFX89852.1 - 0.0033 17.3 1.3 0.006 16.4 1.3 1.4 1 0 0 1 1 1 1 DNA / pantothenate metabolism flavoprotein Wax2_C PF12076.8 KFX89852.1 - 0.0058 16.4 0.1 0.0093 15.7 0.1 1.3 1 0 0 1 1 1 1 WAX2 C-terminal domain ApbA PF02558.16 KFX89852.1 - 0.0076 15.9 0.2 0.013 15.2 0.2 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA NmrA PF05368.13 KFX89852.1 - 0.0096 15.5 2.3 0.33 10.5 2.0 2.2 2 0 0 2 2 2 1 NmrA-like family 3HCDH_N PF02737.18 KFX89852.1 - 0.018 14.9 1.0 0.031 14.1 1.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain GDP_Man_Dehyd PF16363.5 KFX89852.1 - 0.03 13.7 0.1 0.05 13.0 0.1 1.3 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase MFS_1 PF07690.16 KFX89853.1 - 5.1e-36 124.3 34.1 1.6e-35 122.7 33.7 1.8 2 0 0 2 2 2 1 Major Facilitator Superfamily ESSS PF10183.9 KFX89853.1 - 0.032 14.4 0.5 0.7 10.1 0.0 3.1 3 1 1 4 4 4 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) MFS_4 PF06779.14 KFX89853.1 - 0.22 10.8 28.7 3e+02 0.4 28.7 2.7 1 1 0 1 1 1 0 Uncharacterised MFS-type transporter YbfB FAD_binding_3 PF01494.19 KFX89855.1 - 1.4e-14 54.2 0.2 2.5e-07 30.3 0.0 3.0 3 0 0 3 3 3 3 FAD binding domain NAD_binding_8 PF13450.6 KFX89855.1 - 0.0013 18.9 0.0 0.0027 17.9 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KFX89855.1 - 0.0023 17.6 0.1 0.006 16.2 0.0 1.8 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KFX89855.1 - 0.026 13.8 0.0 0.18 11.0 0.0 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KFX89855.1 - 0.036 14.6 0.0 0.28 11.8 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KFX89855.1 - 0.071 13.1 0.0 0.2 11.6 0.0 1.8 1 0 0 1 1 1 0 FAD-NAD(P)-binding TrkA_N PF02254.18 KFX89855.1 - 0.096 12.9 0.0 0.2 11.9 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain Ribosomal_S8e PF01201.22 KFX89857.1 - 2.1e-47 160.8 1.6 2.1e-47 160.8 1.6 1.8 1 1 1 2 2 2 1 Ribosomal protein S8e RIBIOP_C PF04950.12 KFX89857.1 - 0.74 9.2 7.0 1.7 8.0 7.0 1.5 1 1 0 1 1 1 0 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal MscS_TM PF12794.7 KFX89857.1 - 4.9 5.9 4.1 7 5.4 4.1 1.3 1 0 0 1 1 1 0 Mechanosensitive ion channel inner membrane domain 1 Y_phosphatase3 PF13350.6 KFX89858.1 - 1.6e-43 149.3 0.0 6.1e-26 91.8 0.0 2.3 2 1 0 2 2 2 2 Tyrosine phosphatase family Y_phosphatase2 PF03162.13 KFX89858.1 - 2.6e-07 30.4 0.0 2.3e-05 24.0 0.0 2.9 3 0 0 3 3 3 1 Tyrosine phosphatase family Y_phosphatase PF00102.27 KFX89858.1 - 0.0013 18.4 0.0 0.0049 16.5 0.0 1.8 2 0 0 2 2 2 1 Protein-tyrosine phosphatase DSPc PF00782.20 KFX89858.1 - 0.0021 17.9 0.0 0.074 12.9 0.0 2.8 3 0 0 3 3 3 1 Dual specificity phosphatase, catalytic domain Myotub-related PF06602.14 KFX89858.1 - 0.0094 14.9 0.0 0.021 13.8 0.0 1.5 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain ABC_membrane PF00664.23 KFX89859.1 - 1.6e-52 178.8 44.4 4.8e-34 118.3 21.8 3.1 3 0 0 3 3 3 3 ABC transporter transmembrane region ABC_tran PF00005.27 KFX89859.1 - 4.1e-45 153.7 0.0 4.9e-26 91.9 0.0 3.0 2 0 0 2 2 2 2 ABC transporter MMR_HSR1 PF01926.23 KFX89859.1 - 3.4e-06 27.1 1.2 0.033 14.3 0.4 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase Zeta_toxin PF06414.12 KFX89859.1 - 1.3e-05 24.5 0.1 0.0015 17.8 0.0 2.5 2 0 0 2 2 2 1 Zeta toxin AAA_29 PF13555.6 KFX89859.1 - 2.1e-05 24.2 0.5 0.1 12.4 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.6 KFX89859.1 - 2.2e-05 24.9 0.1 0.13 12.6 0.0 2.7 2 0 0 2 2 2 2 AAA ATPase domain SMC_N PF02463.19 KFX89859.1 - 4.5e-05 23.0 1.0 0.3 10.5 0.2 3.4 2 1 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 KFX89859.1 - 0.00026 20.9 0.0 0.97 9.2 0.0 2.6 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_30 PF13604.6 KFX89859.1 - 0.0011 18.7 0.4 0.82 9.3 0.1 2.6 2 0 0 2 2 2 2 AAA domain RsgA_GTPase PF03193.16 KFX89859.1 - 0.0012 18.7 1.1 0.5 10.2 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase DUF87 PF01935.17 KFX89859.1 - 0.0034 17.5 1.7 0.32 11.0 0.4 2.5 2 0 0 2 2 2 1 Helicase HerA, central domain MeaB PF03308.16 KFX89859.1 - 0.0064 15.5 0.9 2 7.3 0.1 2.4 2 0 0 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB IstB_IS21 PF01695.17 KFX89859.1 - 0.027 14.2 0.0 1.1 9.0 0.0 2.4 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_22 PF13401.6 KFX89859.1 - 0.029 14.6 0.8 8.4 6.7 0.1 3.1 2 1 0 2 2 2 0 AAA domain AAA_23 PF13476.6 KFX89859.1 - 0.047 14.2 9.1 2.6 8.5 0.0 3.7 4 0 0 4 4 3 0 AAA domain Ploopntkinase3 PF18751.1 KFX89859.1 - 0.062 13.2 0.3 16 5.4 0.0 2.4 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 Barstar PF01337.18 KFX89859.1 - 0.09 12.8 0.0 0.9 9.6 0.0 2.3 2 0 0 2 2 2 0 Barstar (barnase inhibitor) AAA_28 PF13521.6 KFX89859.1 - 0.14 12.4 0.5 0.85 9.8 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 KFX89859.1 - 0.15 11.6 0.4 2.1 7.8 0.1 2.2 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_15 PF13175.6 KFX89859.1 - 0.33 10.6 2.9 5.8 6.5 0.0 2.7 3 0 0 3 3 3 0 AAA ATPase domain Dynamin_N PF00350.23 KFX89859.1 - 0.55 10.3 12.9 0.32 11.0 0.7 3.3 3 0 0 3 3 3 0 Dynamin family ATP_bind_1 PF03029.17 KFX89859.1 - 1.1 8.9 2.6 14 5.3 0.3 2.5 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein DUF2207 PF09972.9 KFX89859.1 - 7.2 5.3 21.0 0.19 10.5 0.5 3.9 2 1 1 3 3 2 0 Predicted membrane protein (DUF2207) Frag1 PF10277.9 KFX89860.1 - 3.2e-44 151.1 10.3 3.7e-44 150.9 10.3 1.0 1 0 0 1 1 1 1 Frag1/DRAM/Sfk1 family Cyt_bd_oxida_I PF01654.17 KFX89860.1 - 1.6 7.3 9.5 0.077 11.6 0.4 2.4 1 1 1 2 2 2 0 Cytochrome bd terminal oxidase subunit I Cation_ATPase_C PF00689.21 KFX89860.1 - 7 6.3 11.0 1.6 8.4 7.8 1.5 2 0 0 2 2 2 0 Cation transporting ATPase, C-terminus PMT_4TMC PF16192.5 KFX89861.1 - 1.4e-33 116.2 0.5 2.2e-33 115.6 0.5 1.2 1 0 0 1 1 1 1 C-terminal four TMM region of protein-O-mannosyltransferase PMT PF02366.18 KFX89862.1 - 7.5e-85 284.4 16.0 9.5e-85 284.1 16.0 1.1 1 0 0 1 1 1 1 Dolichyl-phosphate-mannose-protein mannosyltransferase MIR PF02815.19 KFX89862.1 - 2.7e-11 43.6 0.2 5.1e-11 42.8 0.2 1.4 1 0 0 1 1 1 1 MIR domain PMT_2 PF13231.6 KFX89862.1 - 0.0023 18.2 11.2 0.0086 16.3 10.7 2.1 1 1 1 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase Pkinase PF00069.25 KFX89864.1 - 2.2e-50 171.5 0.0 3.5e-50 170.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFX89864.1 - 4.2e-28 98.3 0.0 5.7e-28 97.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 KFX89864.1 - 0.0038 16.6 0.0 0.0073 15.7 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 KFX89864.1 - 0.0065 15.8 0.0 0.011 15.0 0.0 1.5 1 1 0 1 1 1 1 Kinase-like APH PF01636.23 KFX89864.1 - 0.06 13.3 0.4 1.1 9.1 0.0 2.7 2 1 1 3 3 3 0 Phosphotransferase enzyme family RIO1 PF01163.22 KFX89864.1 - 0.11 12.0 0.0 0.26 10.8 0.0 1.5 1 0 0 1 1 1 0 RIO1 family NMO PF03060.15 KFX89866.1 - 1.2e-05 24.9 0.1 1.5e-05 24.6 0.1 1.1 1 0 0 1 1 1 1 Nitronate monooxygenase UL42 PF17638.2 KFX89866.1 - 0.075 13.0 0.9 0.67 9.9 0.3 2.0 2 0 0 2 2 2 0 HCMV UL42 RNA_pol_L_2 PF13656.6 KFX89867.1 - 2.5e-24 84.8 0.0 3.2e-24 84.5 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.24 KFX89867.1 - 4.8e-09 35.5 0.1 6.8e-09 35.0 0.1 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain LSM PF01423.22 KFX89868.1 - 7.5e-21 73.6 0.2 8.3e-21 73.5 0.2 1.0 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 KFX89868.1 - 0.008 16.3 0.0 0.0097 16.0 0.0 1.1 1 0 0 1 1 1 1 Ataxin 2 SM domain LSM14 PF12701.7 KFX89868.1 - 0.07 13.2 0.0 0.1 12.7 0.0 1.3 1 1 0 1 1 1 0 Scd6-like Sm domain DNA_pol_A_exo1 PF01612.20 KFX89869.1 - 3.4e-13 49.7 0.0 4.5e-13 49.3 0.0 1.2 1 0 0 1 1 1 1 3'-5' exonuclease PARM PF17061.5 KFX89869.1 - 1.4 9.0 24.8 0.03 14.5 15.6 2.1 2 0 0 2 2 2 0 PARM WD40 PF00400.32 KFX89870.1 - 1.1e-09 38.8 4.1 5.9e-07 30.1 0.1 3.9 4 0 0 4 4 4 2 WD domain, G-beta repeat Nup160 PF11715.8 KFX89870.1 - 0.0054 15.4 0.2 0.1 11.2 0.1 2.0 2 0 0 2 2 2 2 Nucleoporin Nup120/160 ANAPC4_WD40 PF12894.7 KFX89870.1 - 0.01 16.1 0.0 3.4 8.0 0.0 3.1 1 1 2 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain R3H-assoc PF13902.6 KFX89873.1 - 3.6e-05 24.1 0.1 3.6e-05 24.1 0.1 3.2 2 2 1 3 3 3 1 R3H-associated N-terminal domain R3H PF01424.22 KFX89873.1 - 0.02 14.9 0.4 0.29 11.2 0.0 2.7 2 1 0 2 2 2 0 R3H domain Peptidase_M28 PF04389.17 KFX89874.1 - 1.4e-31 109.8 0.1 2.9e-31 108.7 0.0 1.6 2 0 0 2 2 2 1 Peptidase family M28 Peptidase_M20 PF01546.28 KFX89874.1 - 4.7e-07 29.7 0.1 1.3e-06 28.3 0.1 1.8 2 1 0 2 2 2 1 Peptidase family M20/M25/M40 DUF1774 PF08611.10 KFX89876.1 - 4e-36 123.2 1.8 4e-36 123.2 1.8 2.9 4 0 0 4 4 4 1 Fungal protein of unknown function (DUF1774) HMA PF00403.26 KFX89880.1 - 5.9e-15 55.5 0.7 6.9e-15 55.2 0.1 1.4 2 0 0 2 2 2 1 Heavy-metal-associated domain SQHop_cyclase_C PF13243.6 KFX89884.1 - 1.4e-52 178.8 0.9 1.2e-47 162.6 2.4 2.2 2 0 0 2 2 2 2 Squalene-hopene cyclase C-terminal domain SQHop_cyclase_N PF13249.6 KFX89884.1 - 3.6e-36 124.8 7.7 4.3e-33 114.7 0.8 3.9 3 1 1 4 4 4 3 Squalene-hopene cyclase N-terminal domain Prenyltrans PF00432.21 KFX89884.1 - 1.4e-24 85.5 13.9 2.5e-08 33.5 0.3 5.8 5 1 0 5 5 5 3 Prenyltransferase and squalene oxidase repeat Pec_lyase PF09492.10 KFX89884.1 - 0.016 14.5 0.2 3.8 6.7 0.0 3.8 4 0 0 4 4 4 0 Pectic acid lyase TP6A_N PF04406.14 KFX89885.1 - 2.5e-23 81.8 0.0 4.8e-23 80.9 0.0 1.5 1 0 0 1 1 1 1 Type IIB DNA topoisomerase DUF2240 PF09999.9 KFX89885.1 - 0.0057 16.3 0.0 0.019 14.6 0.0 1.8 2 0 0 2 2 2 1 Uncharacterized protein conserved in archaea (DUF2240) Ank_2 PF12796.7 KFX89886.1 - 1.8e-33 115.0 5.3 7.1e-12 45.7 0.1 8.3 7 1 1 8 8 8 6 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KFX89886.1 - 1e-23 83.1 3.6 0.0022 18.2 0.0 8.6 7 1 1 8 8 8 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFX89886.1 - 1.8e-23 80.1 9.7 0.0088 16.5 0.1 10.8 11 0 0 11 11 11 6 Ankyrin repeat Ank_4 PF13637.6 KFX89886.1 - 2e-22 79.2 6.0 0.00049 20.6 0.2 8.8 7 1 1 8 8 8 5 Ankyrin repeats (many copies) Ank PF00023.30 KFX89886.1 - 3.5e-21 74.7 13.7 0.0045 17.4 0.1 9.3 9 1 1 10 10 10 5 Ankyrin repeat TFIIF_alpha PF05793.12 KFX89886.1 - 2.8 6.4 14.3 6.1 5.3 14.3 1.5 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Glyco_hydro_31 PF01055.26 KFX89887.1 - 3.5e-143 478.0 4.8 5.2e-143 477.4 4.8 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.6 KFX89887.1 - 1.1e-23 83.3 2.2 1.1e-23 83.3 0.5 2.0 2 0 0 2 2 2 1 Galactose mutarotase-like DUF5110 PF17137.4 KFX89887.1 - 1.5e-06 28.3 0.2 7.3e-06 26.2 0.1 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF5110) NDK PF00334.19 KFX89888.1 - 3.5e-29 101.5 0.0 4.7e-29 101.1 0.0 1.1 1 0 0 1 1 1 1 Nucleoside diphosphate kinase Mito_carr PF00153.27 KFX89895.1 - 1.5e-55 185.1 0.6 4.3e-19 68.2 0.1 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 KFX89895.1 - 0.015 14.5 0.2 0.38 9.9 0.0 2.1 2 0 0 2 2 2 0 Gammaproteobacterial serine protease UcrQ PF02939.16 KFX89895.1 - 0.036 14.0 0.3 1 9.3 0.0 2.9 3 0 0 3 3 3 0 UcrQ family BTB PF00651.31 KFX89896.1 - 3e-06 27.4 0.0 0.00012 22.3 0.0 2.3 2 0 0 2 2 2 2 BTB/POZ domain FAT PF02259.23 KFX89899.1 - 8e-73 245.6 6.4 1.6e-72 244.6 6.4 1.5 1 0 0 1 1 1 1 FAT domain PI3_PI4_kinase PF00454.27 KFX89899.1 - 8.4e-32 111.0 0.1 1.4e-31 110.2 0.1 1.4 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FATC PF02260.20 KFX89899.1 - 6.9e-06 25.8 0.1 1.4e-05 24.8 0.1 1.5 1 0 0 1 1 1 1 FATC domain TPR_1 PF00515.28 KFX89899.1 - 0.1 12.5 0.6 12 6.0 0.0 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_8 PF13181.6 KFX89899.1 - 1.4 9.3 3.2 7.4 7.1 0.1 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat Fungal_trans PF04082.18 KFX89900.1 - 2.5e-24 85.7 0.0 1.4e-23 83.3 0.0 2.0 2 0 0 2 2 2 1 Fungal specific transcription factor domain 2OG-FeII_Oxy_3 PF13640.6 KFX89900.1 - 1.2e-07 32.5 0.0 3.4e-07 31.1 0.0 1.8 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Zn_clus PF00172.18 KFX89900.1 - 1.5e-06 28.2 13.6 2.7e-06 27.4 13.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF3958 PF13125.6 KFX89900.1 - 0.14 12.4 0.0 0.3 11.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3958) Gal4_dimer PF03902.13 KFX89900.1 - 0.14 12.4 0.2 0.42 10.8 0.0 1.9 2 0 0 2 2 2 0 Gal4-like dimerisation domain Metallophos PF00149.28 KFX89901.1 - 1.6e-14 54.9 0.6 2.5e-14 54.3 0.6 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase PCMT PF01135.19 KFX89902.1 - 5.6e-48 163.5 0.0 6e-47 160.1 0.0 2.1 1 1 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Pkinase PF00069.25 KFX89902.1 - 4.3e-17 62.4 0.0 6.6e-16 58.5 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain Methyltransf_31 PF13847.6 KFX89902.1 - 9.5e-08 32.0 0.1 2.2e-07 30.8 0.1 1.6 1 0 0 1 1 1 1 Methyltransferase domain Pkinase_Tyr PF07714.17 KFX89902.1 - 5.8e-07 29.1 0.0 5.5e-05 22.6 0.0 2.2 2 0 0 2 2 2 1 Protein tyrosine kinase Methyltransf_25 PF13649.6 KFX89902.1 - 0.00012 22.7 0.1 0.0003 21.4 0.1 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.6 KFX89902.1 - 0.00012 22.1 0.0 0.00034 20.6 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 KFX89902.1 - 0.0044 17.6 0.1 0.012 16.3 0.1 1.7 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KFX89902.1 - 0.0087 15.4 0.0 0.017 14.5 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.6 KFX89902.1 - 0.013 15.3 0.0 0.026 14.4 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_3 PF01596.17 KFX89902.1 - 0.041 13.0 0.0 0.095 11.9 0.0 1.5 1 0 0 1 1 1 0 O-methyltransferase RrnaAD PF00398.20 KFX89902.1 - 0.065 12.3 0.0 0.13 11.3 0.0 1.4 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Complex1_LYR_2 PF13233.6 KFX89903.1 - 1.6e-20 73.6 0.0 2e-20 73.3 0.0 1.1 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.15 KFX89903.1 - 2.3e-10 40.4 0.0 4.3e-10 39.5 0.0 1.4 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.6 KFX89903.1 - 0.0023 18.5 0.1 0.0041 17.7 0.1 1.4 1 0 0 1 1 1 1 Complex1_LYR-like TauD PF02668.16 KFX89904.1 - 1.5e-26 93.8 0.0 2.3e-26 93.2 0.0 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Bombolitin PF08096.11 KFX89904.1 - 0.37 11.2 0.0 0.37 11.2 0.0 2.2 2 0 0 2 2 2 0 Bombolitin family MAR_sialic_bdg PF10564.9 KFX89906.1 - 0.16 12.0 0.0 0.2 11.7 0.0 1.2 1 0 0 1 1 1 0 Sialic-acid binding micronemal adhesive repeat Rad9 PF04139.13 KFX89908.1 - 1.8e-49 168.5 0.2 2.2e-49 168.2 0.2 1.0 1 0 0 1 1 1 1 Rad9 LRR_8 PF13855.6 KFX89909.1 - 0.37 10.6 8.0 7.5 6.4 0.2 4.5 3 1 0 3 3 3 0 Leucine rich repeat LRR_4 PF12799.7 KFX89909.1 - 1.2 9.7 21.8 0.74 10.3 1.6 6.3 8 1 1 9 9 9 0 Leucine Rich repeats (2 copies) adh_short PF00106.25 KFX89910.1 - 8.4e-20 71.1 0.3 1.1e-19 70.7 0.3 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KFX89910.1 - 1.7e-16 60.5 0.5 2.1e-16 60.2 0.5 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KFX89910.1 - 9.7e-08 32.1 0.6 2.5e-07 30.8 0.1 1.7 1 1 0 2 2 2 1 KR domain NAD_binding_10 PF13460.6 KFX89910.1 - 0.0017 18.3 0.8 0.0025 17.8 0.8 1.4 1 1 0 1 1 1 1 NAD(P)H-binding CHASE8 PF17152.4 KFX89910.1 - 0.02 15.1 0.0 0.046 13.9 0.0 1.6 1 0 0 1 1 1 0 Periplasmic sensor domain Phos_pyr_kin PF08543.12 KFX89911.1 - 3.4e-82 275.5 2.7 5.1e-82 274.9 2.7 1.3 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase TENA_THI-4 PF03070.16 KFX89911.1 - 1.4e-28 100.2 0.3 2.4e-28 99.4 0.3 1.4 1 0 0 1 1 1 1 TENA/THI-4/PQQC family PfkB PF00294.24 KFX89911.1 - 1.5e-05 24.5 0.3 8.1e-05 22.1 0.3 1.9 1 1 0 1 1 1 1 pfkB family carbohydrate kinase YjeF_N PF03853.15 KFX89911.1 - 0.1 12.4 0.8 14 5.5 0.0 2.4 2 0 0 2 2 2 0 YjeF-related protein N-terminus SDH_sah PF01972.16 KFX89911.1 - 0.11 11.4 0.9 0.22 10.5 0.9 1.4 1 0 0 1 1 1 0 Serine dehydrogenase proteinase HK PF02110.15 KFX89911.1 - 0.17 11.2 4.1 0.38 10.1 0.0 2.8 3 0 0 3 3 3 0 Hydroxyethylthiazole kinase family TENA_THI-4 PF03070.16 KFX89912.1 - 7.7e-13 48.7 0.0 8.3e-13 48.6 0.0 1.0 1 0 0 1 1 1 1 TENA/THI-4/PQQC family LIM PF00412.22 KFX89914.1 - 1.3e-15 57.4 19.6 5.2e-10 39.4 3.9 2.3 2 0 0 2 2 2 2 LIM domain DZR PF12773.7 KFX89914.1 - 0.00017 21.5 17.3 0.042 13.9 1.9 3.9 1 1 1 2 2 2 1 Double zinc ribbon DUF2175 PF09943.9 KFX89914.1 - 0.0011 19.3 5.7 0.24 11.7 0.1 3.1 3 0 0 3 3 3 2 Uncharacterized protein conserved in archaea (DUF2175) TF_Zn_Ribbon PF08271.12 KFX89914.1 - 0.039 13.5 17.7 0.36 10.4 0.9 4.7 3 1 1 4 4 4 0 TFIIB zinc-binding Zn-ribbon_8 PF09723.10 KFX89914.1 - 0.11 12.6 23.4 0.15 12.2 1.3 4.3 2 1 3 5 5 5 0 Zinc ribbon domain Cytochrom_CIII PF02085.16 KFX89914.1 - 0.14 12.5 13.6 2.7 8.4 7.8 2.3 1 1 1 2 2 2 0 Class III cytochrome C family C1_4 PF07975.12 KFX89914.1 - 0.5 10.6 16.0 4.5 7.6 4.6 3.6 3 0 0 3 3 3 0 TFIIH C1-like domain zf-ribbon_3 PF13248.6 KFX89914.1 - 1.4 8.5 21.2 1.5 8.4 2.7 5.8 6 1 0 6 6 6 0 zinc-ribbon domain Cytochrom_c3_2 PF14537.6 KFX89914.1 - 1.4 9.4 19.3 1.7 9.2 6.4 3.2 1 1 0 2 2 2 0 Cytochrome c3 RNHCP PF12647.7 KFX89914.1 - 4.3 7.4 17.9 8.6 6.4 3.9 3.6 2 2 1 3 3 3 0 RNHCP domain Hpt PF01627.23 KFX89919.1 - 1.9e-14 53.7 0.2 8.2e-14 51.6 0.2 1.9 2 0 0 2 2 2 1 Hpt domain ISG65-75 PF11727.8 KFX89919.1 - 0.15 11.3 0.8 0.31 10.2 0.2 1.7 1 1 0 2 2 2 0 Invariant surface glycoprotein SPO22 PF08631.10 KFX89940.1 - 0.018 14.6 0.0 0.023 14.2 0.0 1.1 1 0 0 1 1 1 0 Meiosis protein SPO22/ZIP4 like HMG_box PF00505.19 KFX89941.1 - 2.9e-15 56.4 0.8 6.7e-15 55.3 0.8 1.7 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KFX89941.1 - 3.6e-14 53.1 1.0 9.6e-14 51.7 1.0 1.8 1 0 0 1 1 1 1 HMG-box domain SAM_1 PF00536.30 KFX89941.1 - 3.1e-10 40.4 0.0 5.3e-10 39.6 0.0 1.3 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 KFX89941.1 - 1.6e-07 31.3 0.6 3.7e-07 30.2 0.0 1.9 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) DUF87 PF01935.17 KFX89941.1 - 0.14 12.2 1.4 0.35 10.9 1.5 1.6 2 0 0 2 2 2 0 Helicase HerA, central domain HMG_box_5 PF14887.6 KFX89941.1 - 0.22 11.5 0.9 0.46 10.5 0.6 1.7 1 1 0 1 1 1 0 HMG (high mobility group) box 5 Actino_peptide PF14408.6 KFX89941.1 - 0.68 10.1 0.0 0.68 10.1 0.0 3.1 3 0 0 3 3 3 0 Ribosomally synthesised peptide in actinomycetes FKBP_C PF00254.28 KFX89943.1 - 1.4e-26 92.6 0.1 1.8e-26 92.2 0.1 1.1 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase BATS PF06968.13 KFX89945.1 - 2.6e-21 75.6 0.1 8.4e-21 73.9 0.0 2.0 2 0 0 2 2 2 1 Biotin and Thiamin Synthesis associated domain Radical_SAM PF04055.21 KFX89945.1 - 4e-13 50.1 0.1 9.1e-13 48.9 0.1 1.6 1 0 0 1 1 1 1 Radical SAM superfamily APH PF01636.23 KFX89945.1 - 7.6e-09 35.8 0.0 1.8e-07 31.4 0.0 2.2 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KFX89945.1 - 1e-07 31.8 0.0 1.9e-07 30.9 0.0 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase INPP5B_PH PF16776.5 KFX89945.1 - 0.12 12.1 0.0 0.22 11.2 0.0 1.4 1 0 0 1 1 1 0 Type II inositol 1,4,5-trisphosphate 5-phosphatase PH domain HET PF06985.11 KFX89946.1 - 3.2e-28 98.9 0.0 5.5e-28 98.2 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) APH PF01636.23 KFX89947.1 - 1.6e-11 44.6 1.8 6.8e-10 39.3 1.8 2.1 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KFX89947.1 - 1e-05 25.2 0.1 0.0001 22.0 0.0 2.2 2 0 0 2 2 2 1 Choline/ethanolamine kinase MFS_1 PF07690.16 KFX89948.1 - 4e-45 154.3 38.6 7.8e-45 153.3 38.6 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 KFX89948.1 - 1.4e-10 40.3 11.3 1.4e-10 40.3 11.3 1.6 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Ank_2 PF12796.7 KFX89954.1 - 9e-26 90.3 1.8 2.9e-13 50.2 0.1 2.2 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KFX89954.1 - 8.2e-14 51.8 1.2 2.8e-08 34.1 0.4 2.4 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 KFX89954.1 - 5.3e-13 48.9 2.9 2e-08 34.3 0.2 2.9 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFX89954.1 - 2.7e-12 45.7 0.2 5.1e-07 29.5 0.0 3.1 3 0 0 3 3 3 2 Ankyrin repeat Ank PF00023.30 KFX89954.1 - 1.1e-09 38.3 2.1 1.6e-05 25.1 0.1 2.4 2 0 0 2 2 2 2 Ankyrin repeat ParA PF10609.9 KFX89956.1 - 6.2e-91 304.2 0.1 8e-91 303.9 0.1 1.1 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase CbiA PF01656.23 KFX89956.1 - 1.4e-10 41.3 0.0 6.3e-10 39.2 0.0 1.9 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain MipZ PF09140.11 KFX89956.1 - 1e-06 28.3 0.0 1.4e-05 24.5 0.0 2.0 2 0 0 2 2 2 1 ATPase MipZ AAA_31 PF13614.6 KFX89956.1 - 3e-05 24.0 0.8 0.0011 18.9 0.1 2.3 2 1 0 2 2 2 1 AAA domain ArsA_ATPase PF02374.15 KFX89956.1 - 8e-05 22.0 1.0 0.00012 21.4 0.4 1.5 2 0 0 2 2 2 1 Anion-transporting ATPase MeaB PF03308.16 KFX89956.1 - 0.0015 17.5 0.3 0.0025 16.8 0.3 1.2 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_25 PF13481.6 KFX89956.1 - 0.0043 16.7 0.1 0.0076 15.8 0.1 1.3 1 0 0 1 1 1 1 AAA domain CBP_BcsQ PF06564.12 KFX89956.1 - 0.0045 16.5 0.1 0.011 15.2 0.1 1.6 1 1 0 1 1 1 1 Cellulose biosynthesis protein BcsQ RsgA_GTPase PF03193.16 KFX89956.1 - 0.047 13.6 0.9 0.11 12.4 0.9 1.5 1 0 0 1 1 1 0 RsgA GTPase APS_kinase PF01583.20 KFX89956.1 - 0.071 13.0 0.1 0.12 12.3 0.1 1.3 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA_26 PF13500.6 KFX89956.1 - 0.1 12.4 1.5 3.1 7.6 0.0 2.2 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.22 KFX89956.1 - 0.14 11.4 0.2 0.2 10.8 0.2 1.2 1 0 0 1 1 1 0 NB-ARC domain AAA_16 PF13191.6 KFX89956.1 - 0.2 12.0 0.2 0.45 10.9 0.2 1.5 1 0 0 1 1 1 0 AAA ATPase domain Ribonucleas_3_3 PF14622.6 KFX89957.1 - 4e-23 82.0 0.0 7.6e-23 81.1 0.0 1.5 1 1 0 1 1 1 1 Ribonuclease-III-like Ribonuclease_3 PF00636.26 KFX89957.1 - 0.028 15.0 0.0 0.22 12.2 0.0 2.5 2 1 0 2 2 2 0 Ribonuclease III domain HAT_KAT11 PF08214.11 KFX89958.1 - 9.3e-98 327.7 0.0 1.2e-97 327.4 0.0 1.1 1 0 0 1 1 1 1 Histone acetylation protein Glyco_hydro_16 PF00722.21 KFX89959.1 - 5.9e-44 149.6 0.9 9.1e-44 149.0 0.9 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 TPR_7 PF13176.6 KFX89962.1 - 7.1e-05 22.6 0.9 0.16 12.1 0.3 2.9 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_10 PF13374.6 KFX89962.1 - 0.00019 21.2 0.3 0.089 12.7 0.1 2.9 2 0 0 2 2 2 2 Tetratricopeptide repeat Helo_like_N PF17111.5 KFX89962.1 - 0.00026 20.4 1.8 0.00026 20.4 1.8 1.9 2 1 0 2 2 2 1 Fungal N-terminal domain of STAND proteins TPR_2 PF07719.17 KFX89962.1 - 0.0018 18.3 0.6 1.8 8.9 0.2 2.9 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.6 KFX89962.1 - 0.02 15.6 0.3 4.2 8.5 0.2 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.6 KFX89962.1 - 0.08 13.2 1.8 12 6.3 0.0 3.4 4 0 0 4 4 4 0 Tetratricopeptide repeat Ifi-6-16 PF06140.13 KFX89963.1 - 8.5e-09 35.2 1.2 2.8e-08 33.6 1.2 1.9 1 0 0 1 1 1 1 Interferon-induced 6-16 family DUF2890 PF11081.8 KFX89963.1 - 0.043 13.9 0.4 0.077 13.1 0.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) Esterase_phd PF10503.9 KFX89964.1 - 2.1e-23 83.0 1.5 9.8e-23 80.8 1.5 1.9 1 1 0 1 1 1 1 Esterase PHB depolymerase Peptidase_S9 PF00326.21 KFX89964.1 - 2.6e-13 49.9 1.6 3.5e-13 49.5 1.6 1.1 1 0 0 1 1 1 1 Prolyl oligopeptidase family COesterase PF00135.28 KFX89964.1 - 0.0013 17.7 0.9 0.0055 15.6 0.9 1.8 1 1 0 1 1 1 1 Carboxylesterase family zf-PHD-like PF15446.6 KFX89972.1 - 8.5e-70 233.8 7.1 2.1e-69 232.5 7.1 1.8 1 0 0 1 1 1 1 PHD/FYVE-zinc-finger like domain SNF2_N PF00176.23 KFX89972.1 - 2.3e-54 184.5 0.0 4e-54 183.6 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KFX89972.1 - 1.1e-17 64.3 0.0 2.8e-17 63.0 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HDA2-3 PF11496.8 KFX89972.1 - 2.6e-12 46.5 1.0 7.9e-12 44.9 1.0 1.7 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 Chromo PF00385.24 KFX89972.1 - 1.2e-06 28.3 1.7 0.0011 18.9 0.7 2.9 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain ResIII PF04851.15 KFX89972.1 - 2.7e-06 27.5 0.0 6.2e-06 26.3 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit PHD PF00628.29 KFX89972.1 - 7.5e-06 25.7 3.0 7.5e-06 25.7 3.0 3.3 2 1 1 3 3 3 2 PHD-finger DEAD PF00270.29 KFX89972.1 - 0.00016 21.5 0.0 0.00032 20.5 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF1087 PF06465.13 KFX89972.1 - 0.0026 17.8 0.0 0.0071 16.4 0.0 1.8 1 0 0 1 1 1 1 Domain of Unknown Function (DUF1087) PHD_2 PF13831.6 KFX89972.1 - 0.13 11.9 10.9 0.011 15.3 4.7 2.5 2 1 0 2 2 2 0 PHD-finger PHD_4 PF16866.5 KFX89972.1 - 2.3 8.4 7.1 0.45 10.6 2.4 2.5 2 0 0 2 2 2 0 PHD-finger Zf_RING PF16744.5 KFX89972.1 - 3.4 7.8 5.1 31 4.8 2.4 2.6 2 0 0 2 2 2 0 KIAA1045 RING finger zf-CCCH_6 PF18585.1 KFX89973.1 - 4.1e-26 90.6 0.1 4.1e-26 90.6 0.1 1.7 2 0 0 2 2 2 1 Chromatin remodeling factor Mit1 C-terminal Zn finger 2 zinc_ribbon_5 PF13719.6 KFX89973.1 - 0.36 10.6 2.2 0.94 9.3 2.2 1.6 1 0 0 1 1 1 0 zinc-ribbon domain zf-NADH-PPase PF09297.11 KFX89973.1 - 8.8 6.1 9.6 21 4.9 0.2 3.1 3 0 0 3 3 3 0 NADH pyrophosphatase zinc ribbon domain ECH_1 PF00378.20 KFX89976.1 - 9.2e-26 90.7 0.0 1.4e-25 90.0 0.0 1.2 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KFX89976.1 - 1.9e-11 44.0 0.0 3.3e-11 43.3 0.0 1.3 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase Fungal_trans PF04082.18 KFX89976.1 - 8.6e-08 31.5 0.1 1.7e-07 30.5 0.1 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain PAF-AH_p_II PF03403.13 KFX89988.1 - 5.2e-12 45.0 0.0 1e-07 30.9 0.0 2.1 2 0 0 2 2 2 2 Platelet-activating factor acetylhydrolase, isoform II Chlorophyllase2 PF12740.7 KFX89988.1 - 9.7e-08 31.2 0.0 1.7e-07 30.4 0.0 1.4 1 0 0 1 1 1 1 Chlorophyllase enzyme Hydrolase_4 PF12146.8 KFX89988.1 - 8.4e-05 22.0 0.1 0.0048 16.2 0.0 2.5 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KFX89988.1 - 0.00024 21.8 1.8 0.00037 21.2 1.8 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.7 KFX89988.1 - 0.0006 19.6 0.1 0.7 9.6 0.0 2.4 2 0 0 2 2 2 2 Alpha/beta hydrolase family DLH PF01738.18 KFX89988.1 - 0.017 14.7 0.0 0.031 13.8 0.0 1.4 1 1 0 1 1 1 0 Dienelactone hydrolase family PGAP1 PF07819.13 KFX89988.1 - 0.031 14.0 0.0 0.045 13.5 0.0 1.2 1 0 0 1 1 1 0 PGAP1-like protein Chlorophyllase PF07224.11 KFX89988.1 - 0.073 12.1 0.1 0.92 8.5 0.0 2.1 2 0 0 2 2 2 0 Chlorophyllase Peptidase_S9 PF00326.21 KFX89988.1 - 0.11 11.9 0.3 0.82 9.1 0.1 2.3 2 1 0 2 2 2 0 Prolyl oligopeptidase family Lipase_3 PF01764.25 KFX89988.1 - 0.19 11.6 0.0 0.34 10.7 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) HET PF06985.11 KFX89989.1 - 3.9e-13 50.0 4.0 3.3e-10 40.5 0.6 2.5 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) Glyco_hydro_71 PF03659.14 KFX89990.1 - 1.6e-78 264.2 0.1 1.9e-78 263.9 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 71 MFS_1 PF07690.16 KFX89991.1 - 5.5e-24 84.8 36.3 5.5e-24 84.8 36.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KFX89991.1 - 9.2e-08 31.4 18.2 9.3e-05 21.5 2.3 3.0 2 2 0 2 2 2 2 Sugar (and other) transporter Sugar_tr PF00083.24 KFX89994.1 - 1e-90 304.8 17.5 1.2e-90 304.6 17.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KFX89994.1 - 7.6e-24 84.3 17.0 7.6e-24 84.3 17.0 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 KFX89994.1 - 0.035 13.0 16.5 0.038 12.9 4.2 2.2 2 0 0 2 2 2 0 MFS_1 like family Granulin PF00396.18 KFX89995.1 - 5.4 7.4 21.8 15 6.1 7.5 2.4 1 1 1 2 2 2 0 Granulin SHR3_chaperone PF08229.11 KFX89996.1 - 5.1e-78 260.4 0.0 5.8e-78 260.2 0.0 1.0 1 0 0 1 1 1 1 ER membrane protein SH3 DUF5362 PF17319.2 KFX89996.1 - 0.12 12.3 1.4 0.34 10.8 1.4 1.7 1 1 1 2 2 2 0 Family of unknown function (DUF5362) DUF202 PF02656.15 KFX89996.1 - 0.13 12.8 3.0 7.6 7.1 1.2 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF202) DUF5453 PF17534.2 KFX89996.1 - 0.71 9.8 3.6 1.8 8.5 3.3 1.7 1 1 1 2 2 2 0 Family of unknown function (DUF5453) PAP2 PF01569.21 KFX89997.1 - 1.1e-22 80.3 0.7 4.5e-22 78.3 0.7 2.1 1 1 0 1 1 1 1 PAP2 superfamily PHD PF00628.29 KFX89998.1 - 5.4e-08 32.6 5.2 7.8e-08 32.1 5.2 1.2 1 0 0 1 1 1 1 PHD-finger zf-HC5HC2H PF13771.6 KFX89998.1 - 0.02 15.1 0.5 0.033 14.4 0.5 1.4 1 0 0 1 1 1 0 PHD-like zinc-binding domain TPR_12 PF13424.6 KFX90000.1 - 1.3e-09 38.2 1.8 0.00067 19.9 0.1 4.1 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_19 PF14559.6 KFX90000.1 - 2.5e-06 27.9 0.1 0.031 14.8 0.0 4.1 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_7 PF13176.6 KFX90000.1 - 0.00029 20.7 0.0 11 6.3 0.0 4.9 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_2 PF07719.17 KFX90000.1 - 0.0015 18.5 4.1 7.2 7.0 0.1 5.7 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_10 PF13374.6 KFX90000.1 - 0.0024 17.7 0.0 9.2 6.3 0.0 4.2 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_MalT PF17874.1 KFX90000.1 - 0.0046 16.4 0.1 2.6 7.3 0.0 2.3 1 1 0 2 2 2 2 MalT-like TPR region TPR_4 PF07721.14 KFX90000.1 - 0.0062 17.0 3.3 0.28 11.9 0.4 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat Wzy_C_2 PF11846.8 KFX90000.1 - 0.035 14.0 0.1 0.14 12.0 0.1 1.9 1 1 1 2 2 2 0 Virulence factor membrane-bound polymerase, C-terminal TPR_1 PF00515.28 KFX90000.1 - 0.19 11.6 0.3 7.8 6.5 0.0 3.6 5 0 0 5 5 5 0 Tetratricopeptide repeat Mur_ligase_M PF08245.12 KFX90001.1 - 3.8e-07 30.3 0.0 7.2e-07 29.4 0.0 1.4 1 1 0 1 1 1 1 Mur ligase middle domain Zip PF02535.22 KFX90018.1 - 8.7e-20 71.2 4.7 9.2e-20 71.1 4.7 1.0 1 0 0 1 1 1 1 ZIP Zinc transporter DUF485 PF04341.12 KFX90018.1 - 0.72 9.8 4.1 4.9 7.2 3.4 2.3 1 1 1 2 2 2 0 Protein of unknown function, DUF485 Methyltransf_16 PF10294.9 KFX90021.1 - 1.3e-16 60.8 0.0 1.9e-16 60.3 0.0 1.2 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_25 PF13649.6 KFX90021.1 - 0.0001 22.9 0.0 0.00041 21.0 0.0 2.0 2 1 0 2 2 2 1 Methyltransferase domain PrmA PF06325.13 KFX90021.1 - 0.00012 21.5 0.0 0.00019 20.9 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_23 PF13489.6 KFX90021.1 - 0.00015 21.6 0.0 0.0002 21.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KFX90021.1 - 0.00097 19.7 0.1 0.0067 17.0 0.1 2.2 2 1 0 2 2 2 1 Methyltransferase domain GidB PF02527.15 KFX90021.1 - 0.0063 15.9 0.0 0.0096 15.3 0.0 1.2 1 0 0 1 1 1 1 rRNA small subunit methyltransferase G NNMT_PNMT_TEMT PF01234.17 KFX90021.1 - 0.03 13.5 0.0 0.046 12.9 0.0 1.2 1 0 0 1 1 1 0 NNMT/PNMT/TEMT family Methyltransf_12 PF08242.12 KFX90021.1 - 0.075 13.8 0.1 0.23 12.2 0.1 1.8 1 1 0 1 1 1 0 Methyltransferase domain MTS PF05175.14 KFX90021.1 - 0.081 12.5 0.0 0.29 10.7 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase small domain Methyltransf_31 PF13847.6 KFX90021.1 - 0.19 11.5 0.0 3.7 7.3 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase domain Aldedh PF00171.22 KFX90022.1 - 9.2e-175 581.6 0.6 1e-174 581.4 0.6 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Fungal_trans_2 PF11951.8 KFX90023.1 - 1.5e-35 122.8 0.3 2e-35 122.4 0.3 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KFX90023.1 - 8.5e-08 32.2 9.3 8.5e-08 32.2 9.3 1.6 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ribonuc_L-PSP PF01042.21 KFX90024.1 - 9.8e-20 70.8 0.0 1.2e-19 70.5 0.0 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP AA_permease_2 PF13520.6 KFX90025.1 - 2.1e-31 109.2 27.7 2.8e-31 108.8 27.7 1.1 1 0 0 1 1 1 1 Amino acid permease DUF4381 PF14316.6 KFX90025.1 - 0.094 13.0 1.0 0.14 12.4 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4381) Abhydrolase_9_N PF15420.6 KFX90025.1 - 1 9.3 9.9 4.1 7.3 3.4 3.3 3 1 0 3 3 3 0 Alpha/beta-hydrolase family N-terminus DnaJ PF00226.31 KFX90050.1 - 1.8e-06 27.9 0.1 3.1e-06 27.2 0.1 1.3 1 0 0 1 1 1 1 DnaJ domain Herpes_DNAp_acc PF04929.12 KFX90050.1 - 1.5 7.7 4.4 2 7.3 4.4 1.1 1 0 0 1 1 1 0 Herpes DNA replication accessory factor EF1_GNE PF00736.19 KFX90051.1 - 1.1e-32 112.0 1.0 2e-32 111.2 1.0 1.4 1 0 0 1 1 1 1 EF-1 guanine nucleotide exchange domain EF-1_beta_acid PF10587.9 KFX90051.1 - 3.4e-14 53.0 7.2 9.3e-14 51.6 7.2 1.8 1 0 0 1 1 1 1 Eukaryotic elongation factor 1 beta central acidic region GST_C_3 PF14497.6 KFX90051.1 - 0.0082 16.3 0.1 0.11 12.7 0.0 2.2 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 KFX90051.1 - 0.14 12.4 0.3 0.63 10.3 0.0 2.2 2 1 0 2 2 2 0 Glutathione S-transferase, C-terminal domain TPR_10 PF13374.6 KFX90052.1 - 6.8e-30 102.1 24.6 4.7e-06 26.3 0.3 7.2 7 0 0 7 7 7 6 Tetratricopeptide repeat TPR_12 PF13424.6 KFX90052.1 - 3.3e-27 94.6 17.9 9.3e-10 38.7 0.6 4.7 3 1 1 4 4 4 4 Tetratricopeptide repeat TPR_8 PF13181.6 KFX90052.1 - 3.8e-19 67.2 0.9 0.025 14.7 0.1 6.7 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_7 PF13176.6 KFX90052.1 - 1.9e-14 52.5 2.9 0.11 12.6 0.0 6.4 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_19 PF14559.6 KFX90052.1 - 2.8e-13 50.1 16.3 0.0049 17.3 0.2 6.5 2 1 4 6 6 5 4 Tetratricopeptide repeat TPR_2 PF07719.17 KFX90052.1 - 2.9e-13 48.8 2.7 0.21 11.8 0.1 6.4 6 0 0 6 6 6 3 Tetratricopeptide repeat ANAPC3 PF12895.7 KFX90052.1 - 1.1e-11 44.8 12.2 0.12 12.6 0.1 5.6 1 1 4 5 5 5 5 Anaphase-promoting complex, cyclosome, subunit 3 PPR PF01535.20 KFX90052.1 - 1.1e-10 41.0 0.1 2.6 8.5 0.0 6.3 6 0 0 6 6 6 3 PPR repeat TPR_6 PF13174.6 KFX90052.1 - 4.8e-09 36.3 1.8 5.9 7.8 0.0 6.3 6 0 0 6 6 5 0 Tetratricopeptide repeat TPR_14 PF13428.6 KFX90052.1 - 5.2e-09 36.2 7.7 1.1 10.3 0.1 6.3 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_20 PF14561.6 KFX90052.1 - 7.3e-09 35.9 26.6 0.051 13.9 0.9 6.8 3 1 5 8 8 7 5 Tetratricopeptide repeat TPR_1 PF00515.28 KFX90052.1 - 8.5e-09 34.9 0.9 1.6 8.7 0.0 5.7 5 0 0 5 5 5 2 Tetratricopeptide repeat LCAT PF02450.15 KFX90052.1 - 4.5e-05 22.8 0.0 0.0001 21.6 0.0 1.5 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase Abhydrolase_6 PF12697.7 KFX90052.1 - 0.00035 21.2 0.0 0.00089 19.9 0.0 1.7 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_9 PF10081.9 KFX90052.1 - 0.0004 19.6 0.0 0.0048 16.0 0.0 2.4 2 0 0 2 2 2 1 Alpha/beta-hydrolase family TPR_11 PF13414.6 KFX90052.1 - 0.0006 19.4 1.7 4.8 7.0 0.0 4.9 5 0 0 5 5 5 1 TPR repeat Vps39_1 PF10366.9 KFX90052.1 - 0.0016 18.7 10.1 3.4 8.0 0.9 4.8 1 1 3 4 4 4 1 Vacuolar sorting protein 39 domain 1 LIDHydrolase PF10230.9 KFX90052.1 - 0.0024 17.5 0.2 0.12 11.9 0.0 2.8 3 0 0 3 3 3 1 Lipid-droplet associated hydrolase Hydrolase_4 PF12146.8 KFX90052.1 - 0.0029 16.9 0.0 0.015 14.6 0.0 2.1 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Ribonuc_red_lgN PF00317.21 KFX90052.1 - 0.0032 17.4 1.4 0.74 9.9 0.0 3.8 3 1 0 3 3 3 1 Ribonucleotide reductase, all-alpha domain PPR_2 PF13041.6 KFX90052.1 - 0.0039 17.4 1.2 1.6e+02 2.6 0.0 5.7 6 0 0 6 6 6 0 PPR repeat family TPR_17 PF13431.6 KFX90052.1 - 0.0055 17.0 10.1 13 6.4 0.1 5.6 5 0 0 5 5 5 0 Tetratricopeptide repeat ATP13 PF12921.7 KFX90052.1 - 0.0058 16.5 0.9 9 6.2 0.0 4.2 2 2 1 4 4 3 0 Mitochondrial ATPase expression TPR_9 PF13371.6 KFX90052.1 - 0.0095 16.1 0.9 11 6.2 0.0 4.3 1 1 1 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.6 KFX90052.1 - 0.011 16.3 10.2 0.81 10.4 1.0 5.0 4 1 2 6 6 5 0 Tetratricopeptide repeat Alkyl_sulf_dimr PF14863.6 KFX90052.1 - 0.013 15.9 15.5 3.2 8.2 0.8 5.4 2 1 5 7 7 6 0 Alkyl sulfatase dimerisation PPR_1 PF12854.7 KFX90052.1 - 0.025 14.3 0.0 46 3.8 0.0 4.5 5 0 0 5 5 5 0 PPR repeat PGAP1 PF07819.13 KFX90052.1 - 0.049 13.3 0.0 0.15 11.8 0.0 1.8 1 0 0 1 1 1 0 PGAP1-like protein DpnD-PcfM PF14207.6 KFX90052.1 - 0.054 13.4 16.8 13 5.7 0.3 5.6 5 0 0 5 5 5 0 DpnD/PcfM-like protein AAA_22 PF13401.6 KFX90052.1 - 0.055 13.7 0.0 0.28 11.5 0.0 2.2 1 0 0 1 1 1 0 AAA domain DUF2785 PF10978.8 KFX90052.1 - 0.25 11.1 3.7 15 5.3 0.1 3.5 1 1 2 3 3 3 0 Protein of unknown function (DUF2785) Clathrin PF00637.20 KFX90052.1 - 0.45 10.4 5.2 1.6 8.6 1.1 2.9 2 1 1 3 3 3 0 Region in Clathrin and VPS TPR_4 PF07721.14 KFX90052.1 - 2.3 9.1 13.1 88 4.2 0.2 6.0 6 0 0 6 6 5 0 Tetratricopeptide repeat TPR_3 PF07720.12 KFX90052.1 - 4.2 7.5 12.0 36 4.5 0.2 5.1 5 0 0 5 5 5 0 Tetratricopeptide repeat RPN6_N PF18055.1 KFX90052.1 - 9.3 6.6 9.2 9.1 6.7 1.2 3.1 2 1 1 3 3 3 0 26S proteasome regulatory subunit RPN6 N-terminal domain Mito_carr PF00153.27 KFX90053.1 - 6.7e-37 125.3 10.1 5.9e-16 58.2 0.8 3.7 3 1 0 3 3 3 3 Mitochondrial carrier protein Bromodomain PF00439.25 KFX90054.1 - 1.1e-33 115.1 0.6 8.1e-21 73.9 0.1 2.5 2 0 0 2 2 2 2 Bromodomain BET PF17035.5 KFX90054.1 - 5.4e-11 42.5 0.5 5.4e-11 42.5 0.5 2.5 2 0 0 2 2 2 1 Bromodomain extra-terminal - transcription regulation YlbD_coat PF14071.6 KFX90054.1 - 0.99 9.7 7.7 1.1 9.6 4.1 2.6 2 0 0 2 2 2 0 Putative coat protein PVL_ORF50 PF07768.11 KFX90055.1 - 0.023 15.0 1.1 0.033 14.5 0.3 1.5 2 0 0 2 2 2 0 PVL ORF-50-like family Myc_target_1 PF15179.6 KFX90055.1 - 0.038 13.9 0.4 0.12 12.3 0.4 1.8 1 1 0 1 1 1 0 Myc target protein 1 PHD_4 PF16866.5 KFX90055.1 - 0.14 12.2 0.0 0.27 11.4 0.0 1.4 1 0 0 1 1 1 0 PHD-finger IU_nuc_hydro PF01156.19 KFX90057.1 - 9.6e-59 199.4 0.0 2e-58 198.4 0.0 1.4 1 1 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase LSM PF01423.22 KFX90058.1 - 0.00018 21.2 0.0 0.00025 20.7 0.0 1.2 1 0 0 1 1 1 1 LSM domain Rhomboid PF01694.22 KFX90059.1 - 7.4e-23 81.2 8.5 1.5e-22 80.2 8.5 1.5 1 0 0 1 1 1 1 Rhomboid family PhoD PF09423.10 KFX90059.1 - 2.7e-05 23.3 0.2 0.014 14.4 0.0 3.4 2 1 0 2 2 2 2 PhoD-like phosphatase HHH_5 PF14520.6 KFX90060.1 - 0.01 16.4 0.0 0.02 15.5 0.0 1.5 1 0 0 1 1 1 0 Helix-hairpin-helix domain Sod_Cu PF00080.20 KFX90063.1 - 8.9e-15 55.1 1.3 1.3e-14 54.6 1.3 1.3 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) LSM PF01423.22 KFX90064.1 - 1.3e-21 76.1 0.0 1.4e-21 75.9 0.0 1.0 1 0 0 1 1 1 1 LSM domain LSM14 PF12701.7 KFX90064.1 - 0.003 17.6 0.1 0.0035 17.4 0.1 1.1 1 0 0 1 1 1 1 Scd6-like Sm domain SM-ATX PF14438.6 KFX90064.1 - 0.064 13.4 0.0 0.07 13.3 0.0 1.2 1 0 0 1 1 1 0 Ataxin 2 SM domain VCBS PF13517.6 KFX90068.1 - 5.2e-45 151.9 69.4 4.7e-12 46.3 1.8 8.4 4 2 6 10 10 10 8 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella Lipase_GDSL_2 PF13472.6 KFX90068.1 - 2.1e-11 44.6 0.2 6.8e-11 42.9 0.2 1.9 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family TcdB_toxin_midN PF12256.8 KFX90068.1 - 1.7e-08 34.0 10.4 0.53 9.6 0.0 6.4 5 3 2 7 7 7 4 Insecticide toxin TcdB middle/N-terminal region FG-GAP PF01839.23 KFX90068.1 - 3.9e-07 30.1 37.3 0.24 11.6 0.1 7.4 6 0 0 6 6 6 5 FG-GAP repeat Lipase_GDSL PF00657.22 KFX90068.1 - 3.3e-06 27.2 0.1 5.8e-06 26.4 0.1 1.4 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase C2 PF00168.30 KFX90072.1 - 6.9e-76 251.2 0.3 4.3e-19 68.7 0.0 5.6 5 0 0 5 5 5 5 C2 domain SMP_LBD PF17047.5 KFX90072.1 - 0.0016 17.9 0.0 0.0027 17.2 0.0 1.4 1 0 0 1 1 1 1 Synaptotagmin-like mitochondrial-lipid-binding domain BSP_II PF05432.11 KFX90072.1 - 0.48 10.1 7.5 1 9.0 7.5 1.4 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) TRP PF06011.12 KFX90073.1 - 8.1e-39 133.5 22.1 4.2e-37 127.9 22.1 2.1 1 1 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.6 KFX90073.1 - 1.2e-23 84.1 0.1 1.7e-23 83.5 0.1 1.3 1 0 0 1 1 1 1 ML-like domain DUF639 PF04842.12 KFX90073.1 - 1.4 8.2 5.5 0.12 11.8 0.5 1.7 2 0 0 2 2 2 0 Plant protein of unknown function (DUF639) NAD_binding_8 PF13450.6 KFX90074.1 - 4.9e-08 33.1 0.0 9.3e-08 32.2 0.0 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KFX90074.1 - 7.2e-06 25.8 0.3 1.2e-05 25.0 0.3 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KFX90074.1 - 2e-05 24.0 0.3 7.4e-05 22.1 0.1 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 KFX90074.1 - 6e-05 22.4 0.1 8.6e-05 21.9 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 KFX90074.1 - 0.00014 20.7 0.3 0.00014 20.7 0.3 1.7 2 0 0 2 2 2 1 HI0933-like protein Thi4 PF01946.17 KFX90074.1 - 0.00057 19.2 0.1 0.00086 18.6 0.1 1.2 1 0 0 1 1 1 1 Thi4 family NAD_binding_9 PF13454.6 KFX90074.1 - 0.00059 19.9 0.6 0.0012 18.9 0.1 1.6 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_3 PF13738.6 KFX90074.1 - 0.00069 19.0 0.2 0.001 18.4 0.2 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 KFX90074.1 - 0.0016 17.9 0.2 0.0028 17.1 0.2 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KFX90074.1 - 0.0038 16.4 0.9 0.0038 16.4 0.9 1.8 2 0 0 2 2 2 1 FAD binding domain INTAP PF16617.5 KFX90074.1 - 0.0084 16.4 0.8 0.023 15.0 0.8 1.8 1 1 0 1 1 1 1 Intersectin and clathrin adaptor AP2 binding region Lycopene_cycl PF05834.12 KFX90074.1 - 0.012 14.7 0.2 0.012 14.7 0.2 1.6 2 0 0 2 2 2 0 Lycopene cyclase protein Trp_halogenase PF04820.14 KFX90074.1 - 0.031 13.2 0.1 0.045 12.6 0.1 1.3 1 0 0 1 1 1 0 Tryptophan halogenase AlaDh_PNT_C PF01262.21 KFX90074.1 - 0.078 12.3 0.2 0.14 11.4 0.1 1.5 1 1 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain GIDA PF01134.22 KFX90074.1 - 0.14 11.3 0.1 0.21 10.6 0.1 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A TFIIA PF03153.13 KFX90075.1 - 0.089 12.8 2.9 0.13 12.2 2.9 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Methyltransf_23 PF13489.6 KFX90076.1 - 9.8e-16 58.0 0.0 1.3e-15 57.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KFX90076.1 - 0.043 14.6 0.0 0.062 14.1 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_25 PF13649.6 KFX90076.1 - 0.14 12.8 0.0 0.24 12.1 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Ank_2 PF12796.7 KFX90080.1 - 2e-72 239.8 30.9 6.3e-14 52.3 0.3 8.5 1 1 5 9 9 9 9 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KFX90080.1 - 7e-69 227.4 8.7 4.6e-07 30.3 0.0 15.9 2 2 15 17 17 17 16 Ankyrin repeats (many copies) Ank PF00023.30 KFX90080.1 - 1.4e-58 192.9 41.7 0.0004 20.7 0.0 18.8 19 0 0 19 19 19 13 Ankyrin repeat Ank_3 PF13606.6 KFX90080.1 - 3.3e-49 159.1 18.2 0.0054 17.1 0.0 18.2 19 0 0 19 19 19 14 Ankyrin repeat Ank_5 PF13857.6 KFX90080.1 - 7.7e-27 93.0 20.3 0.00019 21.6 0.1 12.9 7 4 5 13 13 13 9 Ankyrin repeats (many copies) NPV_P10 PF05531.12 KFX90080.1 - 0.0025 18.2 0.4 0.012 16.1 0.1 2.1 1 1 1 2 2 2 1 Nucleopolyhedrovirus P10 protein CLZ PF16526.5 KFX90080.1 - 0.01 16.2 0.0 0.024 15.0 0.0 1.6 1 0 0 1 1 1 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Ad_Cy_reg PF16701.5 KFX90080.1 - 0.061 13.1 2.3 6.5 6.5 0.1 4.4 2 2 2 4 4 4 0 Adenylate cyclase regulatory domain HicA_toxin PF07927.12 KFX90080.1 - 1.8 8.7 8.7 1.2e+02 2.8 0.0 6.5 8 0 0 8 8 8 0 HicA toxin of bacterial toxin-antitoxin, DUF3710 PF12502.8 KFX90080.1 - 2.3 7.8 9.3 21 4.8 0.1 5.5 4 2 2 6 6 6 0 Protein of unknown function (DUF3710) Ins_P5_2-kin PF06090.12 KFX90082.1 - 1.3e-38 133.3 0.0 1.5e-38 133.1 0.0 1.1 1 0 0 1 1 1 1 Inositol-pentakisphosphate 2-kinase Ufd2P_core PF10408.9 KFX90091.1 - 9.6e-210 698.4 11.6 1.2e-209 698.1 11.6 1.1 1 0 0 1 1 1 1 Ubiquitin elongating factor core U-box PF04564.15 KFX90091.1 - 1e-20 73.6 0.8 3.3e-20 72.0 0.8 2.0 1 0 0 1 1 1 1 U-box domain CCDC53 PF10152.9 KFX90091.1 - 5.3 7.4 5.9 80 3.6 4.1 2.8 2 0 0 2 2 2 0 Subunit CCDC53 of WASH complex DUF1977 PF09320.11 KFX90092.1 - 7.5e-30 103.3 0.2 1.4e-29 102.4 0.2 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1977) DnaJ PF00226.31 KFX90092.1 - 8e-19 67.5 0.1 1.5e-18 66.6 0.1 1.5 1 0 0 1 1 1 1 DnaJ domain Acetyltransf_9 PF13527.7 KFX90094.1 - 1.8e-05 24.8 0.1 3.7e-05 23.8 0.0 1.6 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KFX90094.1 - 0.002 18.5 0.0 0.0036 17.7 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KFX90094.1 - 0.045 14.0 0.1 0.087 13.1 0.1 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family Ank_4 PF13637.6 KFX90095.1 - 5.6e-31 106.5 0.3 2.2e-08 34.5 0.1 5.5 4 1 1 5 5 5 4 Ankyrin repeats (many copies) Ank_2 PF12796.7 KFX90095.1 - 2.7e-30 104.8 1.7 9.5e-11 42.1 0.1 4.8 2 1 3 5 5 5 5 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KFX90095.1 - 7.5e-26 89.9 2.2 4.9e-07 29.9 0.0 6.0 4 2 2 6 6 6 5 Ankyrin repeats (many copies) Ank PF00023.30 KFX90095.1 - 1.4e-18 66.4 0.1 0.033 14.6 0.0 7.2 6 0 0 6 6 6 5 Ankyrin repeat Ank_3 PF13606.6 KFX90095.1 - 7.6e-18 62.8 0.1 0.0014 19.0 0.0 8.2 9 0 0 9 9 9 3 Ankyrin repeat FAD_binding_3 PF01494.19 KFX90095.1 - 2.2e-15 56.8 0.1 1.8e-06 27.5 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain DBD_Tnp_Hermes PF10683.9 KFX90095.1 - 0.049 13.3 0.1 0.17 11.6 0.0 1.8 2 0 0 2 2 2 0 Hermes transposase DNA-binding domain DUF2387 PF09526.10 KFX90095.1 - 0.28 11.3 0.6 0.59 10.3 0.6 1.5 1 0 0 1 1 1 0 Probable metal-binding protein (DUF2387) DZR PF12773.7 KFX90095.1 - 0.57 10.2 1.9 4.3 7.4 0.5 2.4 2 0 0 2 2 2 0 Double zinc ribbon DUF974 PF06159.13 KFX90096.1 - 1.5e-46 159.2 0.0 1.6e-46 159.1 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF974) Hydin_ADK PF17213.3 KFX90098.1 - 0.16 12.3 1.2 0.3 11.3 1.2 1.5 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain zinc_ribbon_6 PF14599.6 KFX90099.1 - 8e-26 89.8 0.6 1.2e-25 89.3 0.6 1.3 1 0 0 1 1 1 1 Zinc-ribbon CDC45 PF02724.14 KFX90099.1 - 0.02 13.2 2.0 0.017 13.4 2.0 1.0 1 0 0 1 1 1 0 CDC45-like protein Stc1 PF12898.7 KFX90099.1 - 0.061 13.9 0.2 0.087 13.4 0.2 1.2 1 0 0 1 1 1 0 Stc1 domain Lar_restr_allev PF14354.6 KFX90099.1 - 0.14 12.6 2.0 6 7.3 2.0 3.0 2 1 0 2 2 2 0 Restriction alleviation protein Lar HypA PF01155.19 KFX90099.1 - 0.2 11.7 0.1 0.29 11.2 0.1 1.2 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Rubredoxin_2 PF18073.1 KFX90099.1 - 0.23 11.2 0.6 0.66 9.7 0.6 1.7 1 1 0 1 1 1 0 Rubredoxin metal binding domain NOA36 PF06524.12 KFX90099.1 - 0.4 9.9 18.6 2.1 7.6 14.6 2.1 2 0 0 2 2 2 0 NOA36 protein RNA_pol_3_Rpc31 PF11705.8 KFX90099.1 - 1 9.6 14.7 1.4 9.1 14.7 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 TFIIA PF03153.13 KFX90099.1 - 2.9 7.8 9.0 3 7.8 9.0 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF4637 PF15470.6 KFX90099.1 - 5.3 6.8 6.9 10 5.8 6.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) MOZART1 PF12554.8 KFX90100.1 - 4.3e-23 80.8 1.2 5e-23 80.6 1.2 1.1 1 0 0 1 1 1 1 Mitotic-spindle organizing gamma-tubulin ring associated GFA PF04828.14 KFX90101.1 - 1.9e-16 60.2 0.5 8.3e-16 58.1 0.5 2.0 1 1 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme zf-NADH-PPase PF09297.11 KFX90101.1 - 0.087 12.5 0.6 0.087 12.5 0.6 2.7 3 0 0 3 3 3 0 NADH pyrophosphatase zinc ribbon domain ADK_lid PF05191.14 KFX90101.1 - 0.3 11.1 0.0 0.3 11.1 0.0 2.2 2 1 0 2 2 2 0 Adenylate kinase, active site lid IKI3 PF04762.12 KFX90102.1 - 0 1056.2 0.0 0 1055.8 0.0 1.0 1 0 0 1 1 1 1 IKI3 family ANAPC4_WD40 PF12894.7 KFX90102.1 - 2.1e-05 24.7 0.5 1.9 8.8 0.0 5.2 3 1 1 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain DUF3984 PF13136.6 KFX90103.1 - 3.8e-56 190.9 26.8 7.6e-54 183.3 26.8 2.4 1 1 0 1 1 1 1 Protein of unknown function (DUF3984) PGA2 PF07543.12 KFX90103.1 - 1.2 9.2 5.1 0.71 9.8 2.6 1.8 2 0 0 2 2 2 0 Protein trafficking PGA2 DENN PF02141.21 KFX90106.1 - 1.4e-57 194.6 0.0 2.6e-57 193.8 0.0 1.4 1 0 0 1 1 1 1 DENN (AEX-3) domain uDENN PF03456.18 KFX90106.1 - 2.1e-13 50.8 0.0 8.1e-13 48.9 0.0 2.1 1 0 0 1 1 1 1 uDENN domain dDENN PF03455.19 KFX90106.1 - 2.4e-13 49.9 0.7 8e-13 48.2 0.1 2.3 2 0 0 2 2 2 1 dDENN domain C1_2 PF03107.16 KFX90106.1 - 2.7e-05 24.4 4.5 4.8e-05 23.6 4.5 1.4 1 0 0 1 1 1 1 C1 domain C1_1 PF00130.22 KFX90106.1 - 0.0031 17.4 4.1 0.0052 16.6 4.1 1.3 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) PHD PF00628.29 KFX90106.1 - 0.04 13.8 2.5 0.076 12.9 2.5 1.4 1 0 0 1 1 1 0 PHD-finger Zf_RING PF16744.5 KFX90106.1 - 0.15 12.2 0.9 0.29 11.3 0.9 1.4 1 0 0 1 1 1 0 KIAA1045 RING finger OrfB_Zn_ribbon PF07282.11 KFX90106.1 - 3.7 7.5 5.0 9.4 6.3 5.0 1.6 1 0 0 1 1 1 0 Putative transposase DNA-binding domain TPT PF03151.16 KFX90129.1 - 3.8e-06 26.5 19.2 1.3e-05 24.7 19.2 1.7 1 1 0 1 1 1 1 Triose-phosphate Transporter family CRPA PF05745.11 KFX90129.1 - 0.081 12.9 0.2 0.081 12.9 0.2 1.9 2 0 0 2 2 2 0 Chlamydia 15 kDa cysteine-rich outer membrane protein (CRPA) Tuberculin PF12198.8 KFX90129.1 - 0.11 12.6 0.2 0.22 11.6 0.2 1.5 1 0 0 1 1 1 0 Theoretical tuberculin protein UPF0139 PF03669.13 KFX90129.1 - 0.16 11.8 1.2 0.33 10.8 0.2 2.0 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0139) AMP-binding PF00501.28 KFX90132.1 - 2.4e-64 217.5 0.0 3.3e-64 217.0 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KFX90132.1 - 1.8e-06 28.8 0.1 3.9e-06 27.7 0.1 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain aGPT-Pplase3 PF18746.1 KFX90132.1 - 0.13 11.5 0.5 0.23 10.8 0.5 1.3 1 0 0 1 1 1 0 Alpha-glutamyl/putrescinyl thymine pyrophosphorylase clade 3 Melittin PF01372.17 KFX90132.1 - 0.17 11.9 0.2 0.55 10.3 0.2 1.8 1 0 0 1 1 1 0 Melittin PIG-S PF10510.9 KFX90133.1 - 6e-154 513.7 0.0 7.5e-154 513.3 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylinositol-glycan biosynthesis class S protein Ribosomal_L36 PF00444.18 KFX90134.1 - 1.2e-20 73.4 9.1 2.2e-20 72.5 9.1 1.5 1 0 0 1 1 1 1 Ribosomal protein L36 Complex1_LYR PF05347.15 KFX90135.1 - 3.7e-17 62.1 0.2 5.6e-17 61.5 0.2 1.3 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 KFX90135.1 - 0.0058 17.4 0.0 0.008 16.9 0.0 1.2 1 0 0 1 1 1 1 Complex1_LYR-like Acetyltransf_1 PF00583.25 KFX90136.1 - 4.8e-09 36.5 0.0 5.9e-09 36.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KFX90136.1 - 1e-05 25.5 0.0 1.6e-05 24.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KFX90136.1 - 0.00012 22.0 0.0 0.0002 21.3 0.0 1.2 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_7 PF13508.7 KFX90136.1 - 0.00013 22.3 0.1 0.00019 21.8 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 KFX90136.1 - 0.013 15.7 0.0 0.023 14.8 0.0 1.4 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 KFX90136.1 - 0.13 12.4 0.0 0.2 11.8 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Sec10 PF07393.11 KFX90137.1 - 1.5e-63 215.4 0.4 2.1e-63 214.9 0.1 1.3 2 0 0 2 2 2 1 Exocyst complex component Sec10 GAS PF13851.6 KFX90137.1 - 0.012 14.9 1.0 0.031 13.6 1.0 1.6 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding Ku_PK_bind PF08785.11 KFX90137.1 - 0.03 14.5 0.0 0.066 13.4 0.0 1.6 1 0 0 1 1 1 0 Ku C terminal domain like Baculo_PEP_C PF04513.12 KFX90137.1 - 0.055 13.5 0.1 0.13 12.3 0.1 1.6 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Arg_decarbox_C PF17944.1 KFX90137.1 - 0.18 12.4 0.8 2.4 8.8 0.2 2.8 2 0 0 2 2 2 0 Arginine decarboxylase C-terminal helical extension MCM6_C PF18263.1 KFX90137.1 - 0.92 9.8 4.9 6.1 7.1 0.6 2.6 1 1 1 2 2 2 0 MCM6 C-terminal winged-helix domain Prenyltransf PF01255.19 KFX90138.1 - 0.0062 16.1 0.0 0.3 10.6 0.0 2.1 2 0 0 2 2 2 2 Putative undecaprenyl diphosphate synthase IBR PF01485.21 KFX90139.1 - 6.3e-11 42.3 36.7 2.1e-08 34.3 4.4 3.2 3 0 0 3 3 3 2 IBR domain, a half RING-finger domain MFS_1 PF07690.16 KFX90140.1 - 2.1e-37 128.8 57.2 8.2e-36 123.7 54.2 2.5 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KFX90140.1 - 9.3e-12 44.5 13.7 9.3e-12 44.5 13.7 3.3 2 1 0 3 3 3 2 Sugar (and other) transporter UL42 PF17638.2 KFX90140.1 - 0.1 12.6 0.5 2.4 8.1 0.0 2.6 2 0 0 2 2 2 0 HCMV UL42 TMEM40 PF15817.5 KFX90140.1 - 0.2 11.4 1.9 0.58 9.9 1.9 1.8 1 0 0 1 1 1 0 Transmembrane protein 40 family Ferric_reduct PF01794.19 KFX90148.1 - 2.7e-23 82.5 13.8 6.3e-23 81.2 9.5 2.4 2 0 0 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.12 KFX90148.1 - 3.5e-10 39.9 0.0 6e-10 39.2 0.0 1.3 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.12 KFX90148.1 - 1.6e-07 31.6 0.0 2.2e-07 31.1 0.0 1.2 1 0 0 1 1 1 1 Ferric reductase NAD binding domain Sdh_cyt PF01127.22 KFX90148.1 - 0.00044 20.3 5.8 0.00044 20.3 5.8 3.1 3 1 0 3 3 3 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit NAD_binding_1 PF00175.21 KFX90148.1 - 0.14 12.8 0.0 0.3 11.7 0.0 1.6 1 0 0 1 1 1 0 Oxidoreductase NAD-binding domain FGGY_C PF02782.16 KFX90149.1 - 6.6e-26 91.3 0.0 1.1e-25 90.6 0.0 1.4 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.21 KFX90149.1 - 1e-22 80.9 0.0 1.3e-14 54.4 0.0 2.2 2 0 0 2 2 2 2 FGGY family of carbohydrate kinases, N-terminal domain AhpC-TSA_2 PF13911.6 KFX90151.1 - 7.5e-08 32.5 0.0 1.1e-07 31.9 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA antioxidant enzyme AhpC-TSA PF00578.21 KFX90151.1 - 1.6e-05 24.8 0.0 2.6e-05 24.1 0.0 1.4 1 1 0 1 1 1 1 AhpC/TSA family Pkinase PF00069.25 KFX90152.1 - 1e-67 228.3 0.0 1.4e-67 227.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFX90152.1 - 1.4e-50 172.0 0.0 2.1e-50 171.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KFX90152.1 - 0.0009 18.1 0.0 0.0016 17.3 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 KFX90152.1 - 0.0022 17.4 0.0 0.15 11.3 0.0 2.3 2 0 0 2 2 2 1 Kinase-like ABC1 PF03109.16 KFX90152.1 - 0.024 14.8 0.0 0.055 13.6 0.0 1.5 1 0 0 1 1 1 0 ABC1 family Haspin_kinase PF12330.8 KFX90152.1 - 0.19 10.7 0.0 8.7 5.2 0.0 2.1 2 0 0 2 2 2 0 Haspin like kinase domain FAD_binding_2 PF00890.24 KFX90158.1 - 1.2e-82 278.3 0.1 1.9e-82 277.6 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain Cyt-b5 PF00173.28 KFX90158.1 - 8.1e-23 80.4 0.1 2.1e-21 75.8 0.0 2.6 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain DAO PF01266.24 KFX90158.1 - 7.5e-13 48.8 0.2 2.9e-12 46.8 0.2 1.8 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_oxidored PF12831.7 KFX90158.1 - 1.7e-09 37.5 0.5 5.3e-09 35.9 0.5 1.7 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KFX90158.1 - 1.4e-07 31.1 0.3 1.3e-06 27.9 0.1 2.3 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KFX90158.1 - 2e-07 31.1 1.2 1.2e-06 28.7 0.2 2.8 2 1 1 3 3 3 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 KFX90158.1 - 5.7e-05 22.5 0.0 0.31 10.3 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KFX90158.1 - 0.0001 21.7 0.4 0.022 14.0 0.1 2.5 2 0 0 2 2 2 2 Thi4 family HI0933_like PF03486.14 KFX90158.1 - 0.00057 18.7 4.3 0.015 14.0 0.1 3.1 3 0 0 3 3 3 1 HI0933-like protein GIDA PF01134.22 KFX90158.1 - 0.0021 17.2 1.8 0.26 10.3 0.6 2.2 2 0 0 2 2 2 2 Glucose inhibited division protein A Amino_oxidase PF01593.24 KFX90158.1 - 0.01 15.1 0.7 0.52 9.5 0.1 2.9 3 0 0 3 3 3 0 Flavin containing amine oxidoreductase FAD_binding_3 PF01494.19 KFX90158.1 - 0.019 14.2 1.1 0.054 12.7 0.6 1.8 2 0 0 2 2 2 0 FAD binding domain Pyr_redox PF00070.27 KFX90158.1 - 0.022 15.3 3.1 3.8 8.1 0.3 2.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Ribosomal_60s PF00428.19 KFX90158.1 - 6.7 7.4 9.3 15 6.2 9.3 1.5 1 0 0 1 1 1 0 60s Acidic ribosomal protein Fasciclin PF02469.22 KFX90159.1 - 3.3e-05 24.1 0.0 6.5e-05 23.2 0.0 1.4 1 1 0 1 1 1 1 Fasciclin domain Sin3a_C PF16879.5 KFX90160.1 - 9.2e-67 225.8 5.7 9.2e-67 225.8 5.7 3.3 4 0 0 4 4 4 1 C-terminal domain of Sin3a protein PAH PF02671.21 KFX90160.1 - 4.2e-44 148.4 8.3 8.7e-18 64.2 0.0 4.0 3 0 0 3 3 3 3 Paired amphipathic helix repeat Sin3_corepress PF08295.12 KFX90160.1 - 2.5e-38 130.1 0.0 7.1e-38 128.6 0.0 1.9 1 0 0 1 1 1 1 Sin3 family co-repressor DLIC PF05783.11 KFX90160.1 - 0.069 12.0 0.9 0.15 10.9 0.9 1.5 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) Pollen_allerg_1 PF01357.21 KFX90160.1 - 0.16 12.0 0.2 0.83 9.7 0.2 2.1 2 0 0 2 2 2 0 Pollen allergen DUF2371 PF10177.9 KFX90162.1 - 0.39 10.9 1.1 1.7 8.8 0.1 2.5 3 0 0 3 3 3 0 Uncharacterised conserved protein (DUF2371) Roughex PF06020.11 KFX90162.1 - 4.7 6.2 5.8 8.5 5.4 5.8 1.3 1 0 0 1 1 1 0 Drosophila roughex protein DPM3 PF08285.11 KFX90162.1 - 6.9 6.9 5.9 1.1 9.5 0.0 2.6 3 0 0 3 3 3 0 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) CAF1A PF12253.8 KFX90163.1 - 1.2e-23 83.0 3.6 1.2e-23 83.0 3.6 3.3 2 1 0 2 2 2 1 Chromatin assembly factor 1 subunit A Mitofilin PF09731.9 KFX90163.1 - 0.8 8.5 31.3 1.4 7.7 31.3 1.3 1 0 0 1 1 1 0 Mitochondrial inner membrane protein Borrelia_P83 PF05262.11 KFX90163.1 - 1.6 7.1 39.1 2.6 6.4 39.1 1.3 1 0 0 1 1 1 0 Borrelia P83/100 protein GAGA_bind PF06217.12 KFX90163.1 - 6.2 7.0 14.8 11 6.2 14.8 1.5 1 0 0 1 1 1 0 GAGA binding protein-like family DUF2418 PF10332.9 KFX90166.1 - 5.8e-32 110.1 0.0 1.1e-31 109.2 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2418) Aconitase PF00330.20 KFX90167.1 - 1.1e-159 532.4 0.1 1.5e-159 532.0 0.1 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 KFX90167.1 - 7.4e-41 139.5 0.0 1.3e-40 138.7 0.0 1.4 1 0 0 1 1 1 1 Aconitase C-terminal domain Aconitase_2_N PF06434.13 KFX90167.1 - 0.058 13.0 0.0 0.47 10.1 0.0 2.2 1 1 0 1 1 1 0 Aconitate hydratase 2 N-terminus RabGAP-TBC PF00566.18 KFX90168.1 - 4e-32 111.6 2.6 1.2e-31 110.1 2.6 1.8 1 1 0 1 1 1 1 Rab-GTPase-TBC domain CBM_1 PF00734.18 KFX90173.1 - 5.7e-08 32.6 8.1 1.3e-07 31.5 8.1 1.7 1 0 0 1 1 1 1 Fungal cellulose binding domain Ubiquitin_3 PF14836.6 KFX90174.1 - 0.2 11.7 1.2 0.37 10.8 1.2 1.4 1 0 0 1 1 1 0 Ubiquitin-like domain Pkinase PF00069.25 KFX90176.1 - 1.7e-11 44.0 0.0 2.3e-11 43.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 KFX90176.1 - 4.6e-05 23.4 0.8 8.8e-05 22.5 0.8 1.3 1 1 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_Tyr PF07714.17 KFX90176.1 - 0.00011 21.6 0.0 0.00016 21.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 KFX90176.1 - 0.00059 19.3 0.0 0.00085 18.7 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 KFX90176.1 - 0.016 14.8 0.0 0.027 14.1 0.0 1.3 1 0 0 1 1 1 0 RIO1 family Choline_kinase PF01633.20 KFX90176.1 - 0.15 11.6 0.4 0.25 10.9 0.4 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase STIMATE PF12400.8 KFX90182.1 - 2.1e-41 141.4 4.2 2.6e-41 141.1 4.2 1.1 1 0 0 1 1 1 1 STIMATE family Methyltransf_11 PF08241.12 KFX90186.1 - 6.7e-18 65.1 0.0 1.1e-17 64.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KFX90186.1 - 5.3e-17 62.1 0.0 9e-17 61.4 0.0 1.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KFX90186.1 - 1.8e-14 54.2 0.0 3.4e-14 53.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KFX90186.1 - 5.9e-14 52.5 0.0 1.2e-13 51.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KFX90186.1 - 3.9e-12 46.2 0.0 5.5e-12 45.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_9 PF08003.11 KFX90186.1 - 4.6e-07 29.1 0.0 6.5e-07 28.6 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) PrmA PF06325.13 KFX90186.1 - 1.9e-06 27.5 0.0 2.5e-06 27.1 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Ubie_methyltran PF01209.18 KFX90186.1 - 2.9e-05 23.5 0.0 4e-05 23.1 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family CMAS PF02353.20 KFX90186.1 - 0.00077 18.8 0.0 0.0021 17.4 0.0 1.7 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase NodS PF05401.11 KFX90186.1 - 0.0017 18.0 0.0 0.0024 17.5 0.0 1.2 1 0 0 1 1 1 1 Nodulation protein S (NodS) DREV PF05219.12 KFX90186.1 - 0.037 13.1 0.0 0.05 12.7 0.0 1.2 1 0 0 1 1 1 0 DREV methyltransferase MTS PF05175.14 KFX90186.1 - 0.037 13.6 0.0 0.059 12.9 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain DHBP_synthase PF00926.19 KFX90187.1 - 1.2e-78 263.0 0.0 1.4e-78 262.8 0.0 1.0 1 0 0 1 1 1 1 3,4-dihydroxy-2-butanone 4-phosphate synthase ParB_C PF18064.1 KFX90187.1 - 0.17 12.1 0.2 0.31 11.2 0.2 1.4 1 0 0 1 1 1 0 Centromere-binding protein ParB C-terminal Sec3_C PF09763.9 KFX90188.1 - 6e-213 709.1 7.3 7.9e-213 708.8 7.3 1.1 1 0 0 1 1 1 1 Exocyst complex component Sec3 p450 PF00067.22 KFX90188.1 - 5.9e-39 134.1 0.0 1.6e-38 132.7 0.0 1.6 1 0 0 1 1 1 1 Cytochrome P450 Sec3-PIP2_bind PF15277.6 KFX90188.1 - 1.5e-29 101.9 0.0 3.4e-29 100.8 0.0 1.6 1 0 0 1 1 1 1 Exocyst complex component SEC3 N-terminal PIP2 binding PH Sec3_C_2 PF15278.6 KFX90188.1 - 0.047 14.0 0.0 0.16 12.3 0.0 1.9 1 0 0 1 1 1 0 Sec3 exocyst complex subunit SRP40_C PF05022.12 KFX90189.1 - 7.7e-22 77.9 1.1 7.7e-22 77.9 1.1 3.3 4 0 0 4 4 4 1 SRP40, C-terminal domain DUF755 PF05501.11 KFX90189.1 - 0.0065 16.7 3.8 0.0065 16.7 3.8 7.8 2 1 5 7 7 7 2 Domain of unknown function (DUF755) A_deaminase PF00962.22 KFX90190.1 - 8.3e-24 84.5 0.0 1.2e-23 84.0 0.0 1.2 1 0 0 1 1 1 1 Adenosine/AMP deaminase A_deaminase_N PF08451.11 KFX90190.1 - 0.0021 18.4 0.0 0.0045 17.3 0.0 1.6 1 0 0 1 1 1 1 Adenosine/AMP deaminase N-terminal MIF4G PF02854.19 KFX90195.1 - 9e-62 208.5 0.2 1.4e-28 100.0 0.0 3.3 3 0 0 3 3 3 3 MIF4G domain Upf2 PF04050.14 KFX90195.1 - 1.1e-43 149.2 6.7 1.1e-43 149.2 6.7 2.9 2 0 0 2 2 2 1 Up-frameshift suppressor 2 Fe_dep_repr_C PF02742.15 KFX90198.1 - 0.014 15.5 0.0 1.2 9.2 0.0 2.7 2 0 0 2 2 2 0 Iron dependent repressor, metal binding and dimerisation domain F-box-like PF12937.7 KFX90198.1 - 0.11 12.4 0.2 0.55 10.2 0.0 2.1 2 0 0 2 2 2 0 F-box-like UvdE PF03851.14 KFX90199.1 - 9.7e-108 359.6 0.0 1.2e-107 359.3 0.0 1.1 1 0 0 1 1 1 1 UV-endonuclease UvdE DUF5323 PF17257.2 KFX90199.1 - 6.4 6.7 10.5 25 4.8 3.9 3.4 2 1 1 3 3 3 0 Family of unknown function (DUF5323) DUF1664 PF07889.12 KFX90200.1 - 4 7.5 7.9 3.5 7.7 0.8 3.4 3 1 0 4 4 4 0 Protein of unknown function (DUF1664) Sec1 PF00995.23 KFX90245.1 - 1.9e-105 354.3 0.3 2.4e-105 353.9 0.3 1.1 1 0 0 1 1 1 1 Sec1 family HAD_2 PF13419.6 KFX90247.1 - 1.2e-20 74.4 0.0 2.2e-20 73.5 0.0 1.4 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KFX90247.1 - 4.2e-08 33.7 0.1 6.5e-07 29.8 0.1 2.3 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KFX90247.1 - 4e-06 26.8 0.0 7.5e-06 25.9 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like NIF PF03031.18 KFX90247.1 - 0.00013 21.7 0.0 0.0074 16.1 0.0 2.1 1 1 0 1 1 1 1 NLI interacting factor-like phosphatase GFO_IDH_MocA PF01408.22 KFX90248.1 - 3.5e-11 44.0 0.3 1.1e-10 42.3 0.3 1.9 1 1 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold AMP-binding PF00501.28 KFX90248.1 - 0.075 11.6 0.1 0.12 10.9 0.1 1.3 1 0 0 1 1 1 0 AMP-binding enzyme CoA_binding_2 PF13380.6 KFX90248.1 - 0.076 13.5 0.0 0.15 12.6 0.0 1.4 1 0 0 1 1 1 0 CoA binding domain DHDPS PF00701.22 KFX90249.1 - 3e-34 118.1 0.0 3.5e-34 117.8 0.0 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family Pkinase PF00069.25 KFX90260.1 - 2.4e-50 171.4 0.0 9.4e-50 169.4 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFX90260.1 - 6.4e-21 74.8 0.0 3.6e-20 72.3 0.0 2.1 2 1 0 2 2 2 1 Protein tyrosine kinase UPF0242 PF06785.11 KFX90262.1 - 0.00034 20.8 3.6 0.44 10.6 2.4 2.4 2 0 0 2 2 2 2 Uncharacterised protein family (UPF0242) N-terminus Phage_Mu_Gam PF07352.12 KFX90262.1 - 0.016 15.1 3.1 0.016 15.1 3.1 3.4 4 1 0 4 4 4 0 Bacteriophage Mu Gam like protein Adhesin_P1_N PF18652.1 KFX90262.1 - 0.42 10.7 9.0 0.1 12.6 1.8 2.8 3 0 0 3 3 3 0 Adhesin P1 N-terminal domain Syntaxin-6_N PF09177.11 KFX90262.1 - 0.43 11.1 4.7 3.5 8.2 1.6 3.1 2 1 0 2 2 2 0 Syntaxin 6, N-terminal DUF3496 PF12001.8 KFX90262.1 - 0.83 10.0 4.8 0.76 10.2 2.4 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF3496) TPR_1 PF00515.28 KFX90263.1 - 2.8e-30 102.9 21.7 4.8e-07 29.3 0.1 8.2 9 0 0 9 9 9 7 Tetratricopeptide repeat TPR_2 PF07719.17 KFX90263.1 - 2.6e-28 95.8 31.4 2.7e-05 23.9 0.2 9.5 11 0 0 11 11 9 7 Tetratricopeptide repeat ANAPC3 PF12895.7 KFX90263.1 - 3.4e-28 97.7 21.4 4.4e-23 81.3 1.0 5.7 4 1 2 6 6 6 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.6 KFX90263.1 - 2.8e-19 67.6 16.4 5.8e-05 23.0 0.3 9.2 9 0 0 9 9 9 4 Tetratricopeptide repeat TPR_14 PF13428.6 KFX90263.1 - 2.5e-14 52.7 13.0 0.048 14.5 0.1 8.9 6 3 4 10 10 9 4 Tetratricopeptide repeat TPR_12 PF13424.6 KFX90263.1 - 3.6e-14 52.8 22.0 0.0037 17.5 0.6 8.4 6 3 0 7 7 7 4 Tetratricopeptide repeat TPR_19 PF14559.6 KFX90263.1 - 5.7e-14 52.4 13.6 0.00019 21.9 0.1 6.6 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_11 PF13414.6 KFX90263.1 - 5.4e-13 48.4 18.3 0.0068 16.1 3.0 8.3 7 2 2 9 9 9 4 TPR repeat TPR_16 PF13432.6 KFX90263.1 - 2.6e-12 47.2 17.8 2.3e-06 28.2 0.6 7.4 7 1 1 8 8 8 2 Tetratricopeptide repeat TPR_7 PF13176.6 KFX90263.1 - 4.3e-12 45.2 10.5 0.0096 15.9 0.0 8.1 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_17 PF13431.6 KFX90263.1 - 5e-09 35.9 12.2 3.2 8.3 0.0 8.9 10 0 0 10 10 9 1 Tetratricopeptide repeat TPR_9 PF13371.6 KFX90263.1 - 1.9e-06 27.9 4.9 2.9 8.1 0.1 5.9 5 1 1 6 6 6 2 Tetratricopeptide repeat TPR_6 PF13174.6 KFX90263.1 - 1.8e-05 25.1 19.9 7.2 7.5 0.1 8.8 10 0 0 10 10 9 1 Tetratricopeptide repeat TPR_20 PF14561.6 KFX90263.1 - 0.0016 18.7 3.4 16 5.9 0.0 4.8 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_10 PF13374.6 KFX90263.1 - 0.77 9.7 13.3 16 5.5 0.1 5.8 5 1 1 6 6 6 0 Tetratricopeptide repeat TMEM208_SND2 PF05620.11 KFX90264.1 - 4.7e-51 172.9 0.0 5.7e-51 172.6 0.0 1.0 1 0 0 1 1 1 1 SRP-independent targeting protein 2/TMEM208 CENP-T_C PF15511.6 KFX90265.1 - 8e-09 35.6 0.1 9.7e-09 35.3 0.1 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold Histone PF00125.24 KFX90265.1 - 2.4e-05 24.7 0.1 2.8e-05 24.5 0.1 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TAF PF02969.17 KFX90265.1 - 7.2e-05 22.9 0.1 0.0001 22.4 0.1 1.3 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CBFD_NFYB_HMF PF00808.23 KFX90265.1 - 0.0002 21.6 0.1 0.00035 20.8 0.0 1.5 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-S PF15630.6 KFX90265.1 - 0.0004 20.7 0.1 0.00056 20.2 0.1 1.4 1 1 0 1 1 1 1 CENP-S protein TFIID-31kDa PF02291.15 KFX90265.1 - 0.0085 16.2 0.0 0.01 15.9 0.0 1.1 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 KFX90265.1 - 0.031 14.3 0.0 0.037 14.0 0.0 1.3 1 0 0 1 1 1 0 Bromodomain associated UPF0137 PF03677.13 KFX90265.1 - 0.052 13.3 0.2 0.064 13.0 0.2 1.0 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0137) HIGH_NTase1_ass PF16581.5 KFX90265.1 - 0.11 12.5 0.0 0.12 12.3 0.0 1.1 1 0 0 1 1 1 0 Cytidyltransferase-related C-terminal region CTK3 PF12243.8 KFX90266.1 - 3.3e-46 156.3 0.3 5e-46 155.7 0.3 1.2 1 0 0 1 1 1 1 CTD kinase subunit gamma CTK3 CTK3_C PF12350.8 KFX90266.1 - 1.1e-19 70.4 5.0 1.1e-19 70.4 5.0 1.7 2 0 0 2 2 2 1 CTD kinase subunit gamma CTK3 C-terminus P5CR_dimer PF14748.6 KFX90267.1 - 1.3e-34 118.5 1.1 3.2e-34 117.3 1.0 1.8 2 0 0 2 2 2 1 Pyrroline-5-carboxylate reductase dimerisation F420_oxidored PF03807.17 KFX90267.1 - 6.2e-10 39.5 0.5 1e-08 35.6 0.0 2.4 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent CAP160 PF07918.11 KFX90267.1 - 0.039 13.7 0.3 0.077 12.8 0.3 1.4 1 0 0 1 1 1 0 CAP160 repeat Hat1_N PF10394.9 KFX90268.1 - 8.9e-49 165.8 0.0 1.9e-48 164.7 0.0 1.6 2 0 0 2 2 2 1 Histone acetyl transferase HAT1 N-terminus TMEM131_like PF12371.8 KFX90270.1 - 0.071 13.4 0.0 0.13 12.5 0.0 1.4 1 0 0 1 1 1 0 Transmembrane protein 131-like MFS_1 PF07690.16 KFX90292.1 - 2.4e-40 138.5 25.8 3.5e-40 138.0 25.8 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_2 PF13347.6 KFX90292.1 - 9.1e-10 37.7 12.3 5.6e-06 25.2 0.2 2.5 2 1 0 2 2 2 2 MFS/sugar transport protein OATP PF03137.20 KFX90292.1 - 2.5e-05 22.8 8.7 0.0049 15.2 4.9 3.0 2 1 0 2 2 2 2 Organic Anion Transporter Polypeptide (OATP) family MFS_4 PF06779.14 KFX90292.1 - 3.4e-05 23.3 10.5 3.4e-05 23.3 10.5 2.2 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB MFS_1_like PF12832.7 KFX90292.1 - 0.0033 16.4 11.5 0.0087 15.0 5.5 3.0 2 1 1 3 3 3 2 MFS_1 like family MFS_3 PF05977.13 KFX90292.1 - 0.011 14.2 19.4 0.007 14.8 3.2 2.1 2 0 0 2 2 2 0 Transmembrane secretion effector DUF4680 PF15730.5 KFX90292.1 - 1.2 9.4 4.5 2 8.7 4.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4680) ADH_zinc_N PF00107.26 KFX90294.1 - 1.1e-23 83.6 0.1 1.5e-23 83.2 0.1 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KFX90294.1 - 2.6e-13 51.2 0.0 3.3e-13 50.8 0.0 1.1 1 0 0 1 1 1 1 Zinc-binding dehydrogenase DUF1769 PF08588.10 KFX90295.1 - 6e-25 87.2 0.3 1.1e-24 86.3 0.3 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1769) DUF4568 PF15132.6 KFX90295.1 - 0.16 11.3 0.0 0.28 10.5 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4568) Coat_X PF07552.11 KFX90295.1 - 0.16 11.8 2.3 4.7 7.1 0.3 2.2 2 0 0 2 2 2 0 Spore Coat Protein X and V domain DUF3506 PF12014.8 KFX90296.1 - 2.7e-57 192.7 0.1 2e-56 189.8 0.0 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF3506) F-box-like PF12937.7 KFX90296.1 - 0.00019 21.3 0.3 0.00034 20.4 0.3 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KFX90296.1 - 0.00045 20.0 0.6 0.0008 19.2 0.6 1.4 1 0 0 1 1 1 1 F-box domain Elongin_A PF06881.11 KFX90296.1 - 0.019 15.5 0.0 0.035 14.6 0.0 1.4 1 0 0 1 1 1 0 RNA polymerase II transcription factor SIII (Elongin) subunit A DUF4446 PF14584.6 KFX90297.1 - 0.047 13.7 0.0 0.051 13.5 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4446) WBP-1 PF11669.8 KFX90297.1 - 0.051 14.2 0.0 0.063 13.9 0.0 1.1 1 0 0 1 1 1 0 WW domain-binding protein 1 7TM_GPCR_Srv PF10323.9 KFX90297.1 - 0.058 12.8 0.0 0.066 12.6 0.0 1.0 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srv Shisa PF13908.6 KFX90297.1 - 0.14 12.4 0.0 0.15 12.3 0.0 1.1 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator DUF3408 PF11888.8 KFX90299.1 - 0.034 14.3 0.0 0.039 14.1 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3408) CNH PF00780.22 KFX90304.1 - 4e-71 239.9 0.0 5.7e-71 239.3 0.0 1.2 1 0 0 1 1 1 1 CNH domain RhoGEF PF00621.20 KFX90304.1 - 8.9e-28 97.8 0.6 1.8e-27 96.7 0.6 1.5 1 0 0 1 1 1 1 RhoGEF domain PH_5 PF15405.6 KFX90304.1 - 3.6e-13 49.8 0.1 2.4e-12 47.1 0.1 2.4 1 1 0 1 1 1 1 Pleckstrin homology domain PH PF00169.29 KFX90304.1 - 0.00019 21.9 0.0 0.0022 18.5 0.0 2.4 2 0 0 2 2 2 1 PH domain PH_13 PF16652.5 KFX90304.1 - 0.0025 17.6 0.4 0.68 9.7 0.0 3.2 3 0 0 3 3 3 1 Pleckstrin homology domain PH_16 PF17838.1 KFX90304.1 - 0.021 14.7 0.1 1.6 8.6 0.0 2.6 2 0 0 2 2 2 0 PH domain Mid2 PF04478.12 KFX90306.1 - 6.6e-06 26.0 0.4 6.6e-06 26.0 0.4 2.2 1 1 0 1 1 1 1 Mid2 like cell wall stress sensor DUF4381 PF14316.6 KFX90306.1 - 0.031 14.5 0.0 0.055 13.7 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) Apt1 PF10351.9 KFX90306.1 - 0.034 13.0 8.7 0.038 12.8 8.7 1.3 1 0 0 1 1 1 0 Golgi-body localisation protein domain Presenilin PF01080.17 KFX90306.1 - 0.05 12.4 1.4 0.067 11.9 1.4 1.4 1 0 0 1 1 1 0 Presenilin Utp14 PF04615.13 KFX90306.1 - 0.072 11.7 4.4 0.077 11.6 4.4 1.1 1 0 0 1 1 1 0 Utp14 protein SKG6 PF08693.10 KFX90306.1 - 0.11 11.9 2.1 0.39 10.2 2.1 2.0 1 0 0 1 1 1 0 Transmembrane alpha-helix domain SOG2 PF10428.9 KFX90306.1 - 0.27 10.4 23.5 0.39 9.9 23.5 1.3 1 0 0 1 1 1 0 RAM signalling pathway protein DivIC PF04977.15 KFX90307.1 - 2.9 7.7 5.7 5.5 6.8 5.7 1.4 1 0 0 1 1 1 0 Septum formation initiator rRNA_processing PF08524.11 KFX90312.1 - 0.012 15.7 9.7 0.014 15.5 9.7 1.1 1 0 0 1 1 1 0 rRNA processing OmpH PF03938.14 KFX90312.1 - 0.025 14.9 4.8 0.028 14.8 4.8 1.0 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) ATP-synt_B PF00430.18 KFX90312.1 - 0.18 11.9 8.9 0.21 11.7 8.9 1.1 1 0 0 1 1 1 0 ATP synthase B/B' CF(0) Spc7_N PF15402.6 KFX90312.1 - 1.4 7.1 11.6 1.5 7.0 11.6 1.0 1 0 0 1 1 1 0 N-terminus of kinetochore NMS complex subunit Spc7 YdfA_immunity PF12127.8 KFX90312.1 - 2.9 6.9 4.8 3.6 6.5 4.8 1.1 1 0 0 1 1 1 0 SigmaW regulon antibacterial CBM_1 PF00734.18 KFX90313.1 - 9.4e-09 35.1 2.5 9.4e-09 35.1 2.5 2.7 4 0 0 4 4 4 1 Fungal cellulose binding domain zf-C2H2_4 PF13894.6 KFX90319.1 - 4.1e-07 30.3 2.0 0.0057 17.4 0.1 2.8 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2 PF00096.26 KFX90319.1 - 0.00025 21.3 2.7 0.011 16.1 0.1 2.5 2 0 0 2 2 2 2 Zinc finger, C2H2 type Ima1_N PF09779.9 KFX90319.1 - 0.24 12.2 1.1 1.1 10.1 0.0 2.2 2 0 0 2 2 2 0 Ima1 N-terminal domain HflK_N PF12221.8 KFX90319.1 - 3.4 7.8 11.1 5.7 7.0 0.1 3.7 3 1 0 3 3 3 0 Bacterial membrane protein N terminal Malic_M PF03949.15 KFX90320.1 - 1.1e-94 316.5 0.0 1.6e-94 316.0 0.0 1.2 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.19 KFX90320.1 - 3.8e-63 212.6 0.0 5.7e-63 212.0 0.0 1.3 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain GHL10 PF02638.15 KFX90320.1 - 0.0015 17.7 0.1 0.38 9.8 0.0 2.3 2 0 0 2 2 2 2 Glycosyl hydrolase-like 10 HTH_6 PF01418.17 KFX90321.1 - 0.18 11.8 0.0 0.34 10.9 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain, rpiR family Zn_clus PF00172.18 KFX90322.1 - 0.00013 22.0 10.4 0.00021 21.3 10.4 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF1232 PF06803.12 KFX90341.1 - 0.11 12.3 0.2 0.19 11.6 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1232) INSIG PF07281.12 KFX90342.1 - 1.3e-76 256.9 2.4 1.7e-76 256.6 2.4 1.1 1 0 0 1 1 1 1 Insulin-induced protein (INSIG) N-SET PF11764.8 KFX90343.1 - 1.2e-50 172.0 0.7 1.2e-50 172.0 0.7 2.5 3 0 0 3 3 3 1 COMPASS (Complex proteins associated with Set1p) component N SET_assoc PF11767.8 KFX90343.1 - 5.4e-22 77.2 0.1 1.4e-21 75.9 0.0 1.8 2 0 0 2 2 2 1 Histone lysine methyltransferase SET associated SET PF00856.28 KFX90343.1 - 3.7e-18 66.5 12.6 4e-18 66.4 0.1 4.5 2 2 0 2 2 2 1 SET domain EF-hand_4 PF12763.7 KFX90344.1 - 3.4e-34 116.9 0.0 1.9e-14 53.4 0.0 3.4 3 0 0 3 3 3 3 Cytoskeletal-regulatory complex EF hand EF-hand_7 PF13499.6 KFX90344.1 - 3.2e-09 37.1 0.0 2.7e-05 24.5 0.0 4.0 3 1 0 4 4 4 1 EF-hand domain pair EF-hand_1 PF00036.32 KFX90344.1 - 2.2e-07 30.0 0.0 0.085 12.4 0.0 4.9 5 0 0 5 5 5 1 EF hand EF-hand_6 PF13405.6 KFX90344.1 - 7.5e-05 22.3 0.0 12 6.2 0.0 4.8 5 0 0 5 5 5 0 EF-hand domain Spc7 PF08317.11 KFX90344.1 - 0.0017 17.3 33.8 0.066 12.1 7.6 2.1 1 1 1 2 2 2 2 Spc7 kinetochore protein CCDC144C PF14915.6 KFX90344.1 - 0.0051 16.0 25.8 0.0051 16.0 25.8 1.6 1 1 1 2 2 2 1 CCDC144C protein coiled-coil region EF-hand_8 PF13833.6 KFX90344.1 - 0.027 14.3 0.0 21 5.1 0.0 3.3 3 0 0 3 3 3 0 EF-hand domain pair MAD PF05557.13 KFX90344.1 - 0.063 11.6 24.4 0.09 11.1 24.4 1.1 1 0 0 1 1 1 0 Mitotic checkpoint protein MbeD_MobD PF04899.12 KFX90344.1 - 0.24 11.6 17.5 1.3 9.2 1.0 3.5 1 1 2 3 3 3 0 MbeD/MobD like PRKG1_interact PF15898.5 KFX90344.1 - 0.29 12.1 30.3 0.026 15.4 12.8 3.5 1 1 3 4 4 4 0 cGMP-dependent protein kinase interacting domain DUF3584 PF12128.8 KFX90344.1 - 0.32 8.5 31.3 0.44 8.0 31.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Fib_alpha PF08702.10 KFX90344.1 - 0.48 10.6 20.5 0.069 13.3 8.4 2.3 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family HMMR_N PF15905.5 KFX90344.1 - 0.57 9.6 27.7 1.1 8.7 27.7 1.4 1 0 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal GAS PF13851.6 KFX90344.1 - 0.68 9.2 32.2 0.93 8.8 26.2 2.2 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding CENP-F_leu_zip PF10473.9 KFX90344.1 - 0.69 9.9 30.7 0.55 10.3 18.4 2.5 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 TolA_bind_tri PF16331.5 KFX90344.1 - 0.82 9.8 33.3 0.04 14.0 6.5 3.9 2 1 2 4 4 4 0 TolA binding protein trimerisation CALCOCO1 PF07888.11 KFX90344.1 - 1.2 8.0 30.9 2.4 6.9 30.9 1.4 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like DUF2968 PF11180.8 KFX90344.1 - 1.2 8.8 27.0 1.5 8.4 12.6 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF2968) DUF4763 PF15960.5 KFX90344.1 - 1.2 8.3 22.4 1.8 7.8 7.2 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4763) DUF724 PF05266.14 KFX90344.1 - 1.3 8.8 25.6 0.42 10.4 11.5 2.9 1 1 1 2 2 2 0 Protein of unknown function (DUF724) ATG16 PF08614.11 KFX90344.1 - 1.3 9.2 40.4 0.59 10.3 20.5 3.0 1 1 2 3 3 3 0 Autophagy protein 16 (ATG16) Tup_N PF08581.10 KFX90344.1 - 1.6 9.1 16.4 0.42 10.9 3.9 2.6 1 1 1 2 2 2 0 Tup N-terminal DUF1664 PF07889.12 KFX90344.1 - 2.3 8.3 15.6 0.64 10.1 7.3 2.3 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) DUF4239 PF14023.6 KFX90344.1 - 2.5 7.7 4.8 4.6 6.9 4.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4239) TPR_MLP1_2 PF07926.12 KFX90344.1 - 2.7 8.1 38.7 1 9.4 19.3 2.9 1 1 2 3 3 3 0 TPR/MLP1/MLP2-like protein FAD-SLDH PF12318.8 KFX90344.1 - 2.8 8.0 14.5 0.77 9.8 3.7 2.7 1 1 1 2 2 2 0 Membrane bound FAD containing D-sorbitol dehydrogenase TMF_TATA_bd PF12325.8 KFX90344.1 - 3 8.1 26.6 0.12 12.6 3.9 3.2 1 1 2 3 3 3 0 TATA element modulatory factor 1 TATA binding Golgin_A5 PF09787.9 KFX90344.1 - 3 7.2 33.1 0.24 10.8 26.2 1.9 1 1 1 2 2 2 0 Golgin subfamily A member 5 FUSC PF04632.12 KFX90344.1 - 4.9 5.6 11.0 7.7 4.9 11.0 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family SKA1 PF07160.12 KFX90344.1 - 5.2 6.8 23.8 0.31 10.9 8.8 2.4 1 1 1 2 2 2 0 Spindle and kinetochore-associated protein 1 LPP PF04728.13 KFX90344.1 - 5.9 7.4 16.8 0.81 10.1 1.1 3.7 3 1 2 5 5 4 0 Lipoprotein leucine-zipper Allexi_40kDa PF05549.11 KFX90344.1 - 6.1 6.3 18.1 3.5 7.1 3.4 2.5 1 1 1 2 2 2 0 Allexivirus 40kDa protein COG2 PF06148.11 KFX90344.1 - 6.2 6.9 16.5 0.4 10.8 5.0 2.5 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Occludin_ELL PF07303.13 KFX90344.1 - 6.2 7.6 13.4 7.6 7.3 4.9 2.5 1 1 1 2 2 2 0 Occludin homology domain Macoilin PF09726.9 KFX90344.1 - 6.3 5.2 26.1 0.026 13.1 17.2 1.5 2 0 0 2 2 1 0 Macoilin family Tubulin PF00091.25 KFX90345.1 - 2.6e-67 226.8 0.0 3.7e-67 226.3 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 KFX90345.1 - 9.4e-50 168.0 0.1 1.8e-49 167.1 0.1 1.5 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 KFX90345.1 - 0.0026 17.5 0.0 0.006 16.3 0.0 1.6 1 0 0 1 1 1 1 Tubulin domain Pga1 PF10333.9 KFX90346.1 - 2.5e-05 24.2 0.5 5.7e-05 23.0 0.3 2.0 1 1 0 1 1 1 1 GPI-Mannosyltransferase II co-activator UPF0121 PF03661.13 KFX90358.1 - 4.4e-29 101.6 5.2 6.1e-29 101.1 5.2 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0121) Palm_thioest PF02089.15 KFX90359.1 - 1.3e-80 270.7 0.0 1.5e-80 270.5 0.0 1.0 1 0 0 1 1 1 1 Palmitoyl protein thioesterase DUF915 PF06028.11 KFX90359.1 - 0.0026 17.1 0.0 0.0047 16.3 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF915) Cyclin_N PF00134.23 KFX90360.1 - 4.3e-09 36.2 0.4 1.9e-06 27.7 0.0 2.5 1 1 2 3 3 3 2 Cyclin, N-terminal domain UreF PF01730.16 KFX90361.1 - 9.1e-22 78.1 1.1 1.4e-21 77.5 0.4 1.7 2 0 0 2 2 2 1 UreF Ifi-6-16 PF06140.13 KFX90361.1 - 0.0037 17.1 10.7 0.0098 15.8 10.5 1.8 1 1 0 1 1 1 1 Interferon-induced 6-16 family DUF429 PF04250.13 KFX90361.1 - 0.015 15.1 0.1 0.03 14.1 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF429) PKcGMP_CC PF16808.5 KFX90361.1 - 1.2 9.0 3.1 0.62 10.0 1.0 1.6 2 0 0 2 2 2 0 Coiled-coil N-terminus of cGMP-dependent protein kinase TcdA_TcdB_pore PF12920.7 KFX90361.1 - 1.6 6.9 3.1 2.1 6.5 3.1 1.1 1 0 0 1 1 1 0 TcdA/TcdB pore forming domain Cut12 PF11500.8 KFX90362.1 - 9.7e-36 122.9 12.3 9.7e-36 122.9 12.3 3.8 2 2 1 3 3 3 1 Spindle pole body formation-associated protein Ifi-6-16 PF06140.13 KFX90362.1 - 4.2e-08 33.0 15.9 7.8e-08 32.1 15.9 1.4 1 0 0 1 1 1 1 Interferon-induced 6-16 family DUF4266 PF14086.6 KFX90362.1 - 0.097 13.6 0.8 0.54 11.3 0.8 2.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4266) YabA PF06156.13 KFX90362.1 - 7.1 7.3 17.5 1.1 9.9 4.0 3.7 1 1 2 3 3 3 0 Initiation control protein YabA UQ_con PF00179.26 KFX90363.1 - 4.4e-38 130.1 0.0 5.5e-38 129.8 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme LRR_6 PF13516.6 KFX90364.1 - 0.011 15.7 0.0 43 4.5 0.0 4.9 4 0 0 4 4 4 0 Leucine Rich repeat TAL_FSA PF00923.19 KFX90369.1 - 2.2e-94 316.0 0.2 2.5e-94 315.8 0.2 1.0 1 0 0 1 1 1 1 Transaldolase/Fructose-6-phosphate aldolase C5-epim_C PF06662.13 KFX90369.1 - 0.014 14.9 0.0 0.025 14.1 0.0 1.4 1 1 0 1 1 1 0 D-glucuronyl C5-epimerase C-terminus BTB_3 PF16017.5 KFX90369.1 - 0.11 12.7 0.0 0.32 11.1 0.0 1.8 2 0 0 2 2 2 0 BTB/POZ domain bZIP_2 PF07716.15 KFX90372.1 - 3.9e-12 46.1 9.2 8.2e-12 45.0 9.2 1.6 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.21 KFX90372.1 - 0.0095 16.0 8.8 0.018 15.1 8.8 1.4 1 0 0 1 1 1 1 bZIP transcription factor XhlA PF10779.9 KFX90372.1 - 0.012 15.7 0.9 0.024 14.8 0.9 1.4 1 0 0 1 1 1 0 Haemolysin XhlA LCD1 PF09798.9 KFX90372.1 - 0.11 11.0 1.2 0.11 11.0 1.2 1.1 1 0 0 1 1 1 0 DNA damage checkpoint protein betaPIX_CC PF16523.5 KFX90372.1 - 0.34 10.7 3.6 0.56 10.1 3.6 1.4 1 0 0 1 1 1 0 betaPIX coiled coil ABC_membrane PF00664.23 KFX90374.1 - 2.9e-85 286.3 28.2 6.1e-43 147.4 9.8 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 KFX90374.1 - 8.8e-62 207.6 0.0 9.3e-32 110.4 0.0 2.4 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 KFX90374.1 - 3.3e-12 46.3 2.0 5.3e-05 22.8 1.6 4.2 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 KFX90374.1 - 8.9e-07 29.3 0.0 0.44 10.8 0.0 3.9 4 0 0 4 4 4 2 AAA domain AAA_29 PF13555.6 KFX90374.1 - 9.6e-07 28.5 0.4 0.013 15.2 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.6 KFX90374.1 - 5.2e-06 27.0 1.8 0.053 13.9 0.1 3.2 2 1 0 2 2 2 2 AAA ATPase domain RsgA_GTPase PF03193.16 KFX90374.1 - 5.1e-05 23.2 0.0 0.061 13.2 0.0 2.7 3 0 0 3 3 2 2 RsgA GTPase DUF87 PF01935.17 KFX90374.1 - 6.6e-05 23.1 2.6 0.0018 18.4 0.2 2.7 3 0 0 3 3 3 1 Helicase HerA, central domain AAA_18 PF13238.6 KFX90374.1 - 0.00016 22.2 0.0 1 9.9 0.0 2.5 2 0 0 2 2 2 2 AAA domain Zeta_toxin PF06414.12 KFX90374.1 - 0.00019 20.8 0.0 0.088 12.1 0.0 2.4 2 0 0 2 2 2 1 Zeta toxin AAA_23 PF13476.6 KFX90374.1 - 0.00027 21.5 0.0 0.42 11.1 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_33 PF13671.6 KFX90374.1 - 0.00037 20.7 0.0 0.66 10.1 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.6 KFX90374.1 - 0.00048 19.8 0.1 0.2 11.2 0.0 2.9 3 0 0 3 3 3 1 AAA domain AAA_30 PF13604.6 KFX90374.1 - 0.00052 19.8 0.3 0.22 11.3 0.0 3.4 3 0 0 3 3 3 1 AAA domain AAA_21 PF13304.6 KFX90374.1 - 0.0014 18.6 1.1 0.3 10.9 0.0 3.0 4 0 0 4 4 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA PF00004.29 KFX90374.1 - 0.0018 18.7 0.1 21 5.5 0.1 4.2 4 0 0 4 4 4 0 ATPase family associated with various cellular activities (AAA) APS_kinase PF01583.20 KFX90374.1 - 0.0022 17.9 0.1 0.7 9.8 0.1 2.5 2 0 0 2 2 2 1 Adenylylsulphate kinase SbcCD_C PF13558.6 KFX90374.1 - 0.0074 16.5 1.3 9.8 6.5 0.3 3.6 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit MMR_HSR1 PF01926.23 KFX90374.1 - 0.0085 16.2 2.1 1.9 8.6 0.0 3.2 3 0 0 3 3 3 1 50S ribosome-binding GTPase ABC_ATPase PF09818.9 KFX90374.1 - 0.011 14.6 3.2 0.65 8.7 0.0 3.7 4 0 0 4 4 4 0 Predicted ATPase of the ABC class AAA_24 PF13479.6 KFX90374.1 - 0.011 15.4 0.0 1.9 8.2 0.0 2.3 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.22 KFX90374.1 - 0.023 13.9 0.2 6.8 5.8 0.0 2.5 2 0 0 2 2 2 0 NB-ARC domain AAA_15 PF13175.6 KFX90374.1 - 0.043 13.5 0.1 0.48 10.1 0.0 2.0 2 0 0 2 2 2 0 AAA ATPase domain DUF3987 PF13148.6 KFX90374.1 - 0.046 12.7 0.1 6.9 5.6 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3987) AAA_17 PF13207.6 KFX90374.1 - 0.051 14.0 0.0 12 6.3 0.0 2.8 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 KFX90374.1 - 0.055 13.0 0.0 5.1 6.6 0.0 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_5 PF07728.14 KFX90374.1 - 0.064 13.3 0.1 7 6.7 0.0 2.9 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) Egh16-like PF11327.8 KFX90375.1 - 8.4e-58 195.8 11.1 8.4e-58 195.8 11.1 2.0 2 0 0 2 2 2 1 Egh16-like virulence factor Tic110 PF16940.5 KFX90375.1 - 0.38 9.2 4.2 0.48 8.8 4.2 1.1 1 0 0 1 1 1 0 Chloroplast envelope transporter GGACT PF06094.12 KFX90376.1 - 1e-11 45.5 0.0 1.4e-11 45.1 0.0 1.2 1 0 0 1 1 1 1 Gamma-glutamyl cyclotransferase, AIG2-like Esterase_phd PF10503.9 KFX90377.1 - 4e-18 65.7 1.3 7e-18 64.9 1.3 1.3 1 0 0 1 1 1 1 Esterase PHB depolymerase CBM_1 PF00734.18 KFX90377.1 - 1.9e-12 46.9 15.3 1.9e-12 46.9 15.3 2.5 3 0 0 3 3 3 1 Fungal cellulose binding domain Peptidase_S9 PF00326.21 KFX90377.1 - 3.6e-12 46.2 1.0 8e-12 45.1 1.0 1.5 1 0 0 1 1 1 1 Prolyl oligopeptidase family COesterase PF00135.28 KFX90377.1 - 0.00076 18.5 0.2 0.00076 18.5 0.2 1.4 2 0 0 2 2 2 1 Carboxylesterase family Hydrolase_4 PF12146.8 KFX90377.1 - 0.22 10.8 0.1 17 4.5 0.0 2.1 2 0 0 2 2 2 0 Serine aminopeptidase, S33 MFS_1 PF07690.16 KFX90378.1 - 9.8e-18 64.2 26.7 9.8e-18 64.2 26.7 1.8 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KFX90378.1 - 8.1e-05 21.7 6.5 8.1e-05 21.7 6.5 3.0 1 1 2 3 3 3 1 Sugar (and other) transporter Tmemb_170 PF10190.9 KFX90378.1 - 0.37 11.2 5.6 0.18 12.2 0.6 2.8 2 0 0 2 2 2 0 Putative transmembrane protein 170 ArabFuran-catal PF09206.11 KFX90379.1 - 6.2e-148 492.3 13.9 8.6e-148 491.8 13.9 1.2 1 0 0 1 1 1 1 Alpha-L-arabinofuranosidase B, catalytic AbfB PF05270.13 KFX90379.1 - 5.7e-57 191.6 3.8 8.6e-57 191.1 3.8 1.3 1 0 0 1 1 1 1 Alpha-L-arabinofuranosidase B (ABFB) domain F-box PF00646.33 KFX90380.1 - 9e-05 22.2 1.0 0.00021 21.1 1.0 1.6 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 KFX90380.1 - 0.002 18.0 0.2 0.0044 16.9 0.2 1.6 1 0 0 1 1 1 1 F-box-like F-box_4 PF15966.5 KFX90380.1 - 0.082 12.8 0.1 0.18 11.7 0.1 1.5 1 0 0 1 1 1 0 F-box ANAPC8 PF04049.13 KFX90382.1 - 1.5e-56 190.3 1.0 3.6e-56 189.1 0.1 1.9 2 0 0 2 2 2 1 Anaphase promoting complex subunit 8 / Cdc23 TPR_1 PF00515.28 KFX90382.1 - 9.5e-21 72.7 3.2 0.0001 21.9 0.0 7.8 8 0 0 8 8 8 4 Tetratricopeptide repeat TPR_8 PF13181.6 KFX90382.1 - 3.9e-19 67.2 6.4 6.8e-05 22.8 0.0 7.2 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_2 PF07719.17 KFX90382.1 - 1.6e-16 59.0 20.3 0.013 15.6 0.0 9.8 10 0 0 10 10 10 4 Tetratricopeptide repeat TPR_14 PF13428.6 KFX90382.1 - 4.1e-13 49.0 21.0 0.0057 17.4 0.1 9.2 8 2 2 10 10 9 3 Tetratricopeptide repeat TPR_12 PF13424.6 KFX90382.1 - 2.7e-10 40.4 18.8 0.064 13.6 0.0 7.7 9 0 0 9 9 8 4 Tetratricopeptide repeat TPR_11 PF13414.6 KFX90382.1 - 9.1e-09 34.9 2.8 1.4e-06 27.9 0.1 3.7 3 1 1 4 4 4 2 TPR repeat TPR_16 PF13432.6 KFX90382.1 - 2e-08 34.8 7.2 1.9e-05 25.2 0.2 5.8 5 1 1 6 6 6 1 Tetratricopeptide repeat TPR_9 PF13371.6 KFX90382.1 - 3.5e-07 30.3 18.0 0.025 14.7 0.3 6.0 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_7 PF13176.6 KFX90382.1 - 7.5e-07 28.8 12.6 0.013 15.5 0.0 6.5 7 0 0 7 7 7 2 Tetratricopeptide repeat ANAPC3 PF12895.7 KFX90382.1 - 6.5e-05 23.1 7.6 0.0061 16.8 0.4 5.6 6 0 0 6 6 6 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.6 KFX90382.1 - 8.1e-05 23.1 9.0 2.8 8.5 0.0 6.8 7 1 0 7 7 7 1 Tetratricopeptide repeat DUF3856 PF12968.7 KFX90382.1 - 0.00022 21.3 3.5 0.0062 16.6 0.0 3.3 4 1 0 4 4 4 1 Domain of Unknown Function (DUF3856) TPR_10 PF13374.6 KFX90382.1 - 0.00099 18.9 11.4 0.58 10.1 0.4 5.2 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_17 PF13431.6 KFX90382.1 - 0.0024 18.1 0.0 9 6.9 0.0 4.7 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_6 PF13174.6 KFX90382.1 - 0.22 12.2 19.1 27 5.7 0.4 8.5 10 0 0 10 10 9 0 Tetratricopeptide repeat polyprenyl_synt PF00348.17 KFX90383.1 - 4.9e-92 307.6 0.0 6.6e-92 307.2 0.0 1.2 1 0 0 1 1 1 1 Polyprenyl synthetase XRCC4 PF06632.12 KFX90385.1 - 4.4e-09 35.7 20.0 4.3e-08 32.4 19.8 2.0 1 1 0 1 1 1 1 DNA double-strand break repair and V(D)J recombination protein XRCC4 PPP4R2 PF09184.11 KFX90385.1 - 0.17 11.5 15.5 0.32 10.5 15.5 1.4 1 0 0 1 1 1 0 PPP4R2 PUF PF00806.19 KFX90386.1 - 4.4e-37 123.7 1.9 9.7e-06 25.0 0.0 8.8 9 0 0 9 9 9 7 Pumilio-family RNA binding repeat RraB PF06877.11 KFX90386.1 - 0.054 14.2 0.0 0.23 12.2 0.0 2.0 2 0 0 2 2 2 0 Regulator of ribonuclease activity B RasGEF PF00617.19 KFX90386.1 - 0.055 13.7 0.0 0.38 10.9 0.0 2.3 1 1 0 2 2 2 0 RasGEF domain DUF2730 PF10805.8 KFX90386.1 - 0.14 12.3 0.4 0.33 11.1 0.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2730) MRP-S33 PF08293.11 KFX90387.1 - 1.6e-31 108.4 0.1 1.6e-31 108.4 0.1 1.7 2 0 0 2 2 2 1 Mitochondrial ribosomal subunit S27 Ribonuclease_3 PF00636.26 KFX90388.1 - 4.8e-13 49.6 0.1 2.4e-12 47.4 0.0 2.2 2 0 0 2 2 2 1 Ribonuclease III domain Ribonucleas_3_3 PF14622.6 KFX90388.1 - 1.1e-09 38.5 0.0 2.7e-09 37.3 0.0 1.6 1 0 0 1 1 1 1 Ribonuclease-III-like dsrm PF00035.26 KFX90388.1 - 0.4 11.4 0.0 0.4 11.4 0.0 3.1 3 1 0 3 3 3 0 Double-stranded RNA binding motif Glyco_hydro_43 PF04616.14 KFX90389.1 - 2.6e-71 240.3 0.4 4e-71 239.7 0.4 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 GH43_C2 PF17851.1 KFX90389.1 - 4.5e-11 42.9 0.0 1.3e-10 41.4 0.1 1.7 2 0 0 2 2 2 1 Beta xylosidase C-terminal Concanavalin A-like domain 4HBT PF03061.22 KFX90389.1 - 5.5e-08 33.1 0.1 1.1e-07 32.1 0.1 1.6 1 0 0 1 1 1 1 Thioesterase superfamily DUF4176 PF13780.6 KFX90389.1 - 0.62 10.2 2.2 23 5.1 0.0 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4176) Sugar_tr PF00083.24 KFX90390.1 - 1.7e-74 251.3 21.5 2e-74 251.1 21.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KFX90390.1 - 5.8e-26 91.3 25.6 9.9e-20 70.7 6.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 KFX90390.1 - 3.2e-06 25.9 2.3 3.2e-06 25.9 2.3 2.1 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) MgtC PF02308.16 KFX90390.1 - 2.1 8.7 9.7 0.16 12.4 0.5 3.1 2 1 0 3 3 3 0 MgtC family BC10 PF06726.12 KFX90391.1 - 1.8e-16 60.1 10.6 3.6e-16 59.1 10.6 1.5 1 0 0 1 1 1 1 Bladder cancer-related protein BC10 Reovirus_L2 PF06016.11 KFX90391.1 - 0.17 9.0 0.0 0.22 8.7 0.0 1.0 1 0 0 1 1 1 0 Reovirus core-spike protein lambda-2 (L2) Ge1_WD40 PF16529.5 KFX90392.1 - 0.00097 18.2 0.0 0.0024 16.9 0.0 1.6 1 0 0 1 1 1 1 WD40 region of Ge1, enhancer of mRNA-decapping protein DZF PF07528.14 KFX90392.1 - 0.027 14.1 2.6 0.036 13.7 0.6 2.2 1 1 1 2 2 2 0 DZF domain DUF1664 PF07889.12 KFX90392.1 - 0.23 11.5 9.7 0.44 10.6 1.3 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) BAR_3 PF16746.5 KFX90392.1 - 0.67 9.6 7.3 0.1 12.3 0.8 2.6 2 1 0 2 2 2 0 BAR domain of APPL family PhoU PF01895.19 KFX90392.1 - 0.93 10.0 2.5 30 5.2 0.3 3.0 2 0 0 2 2 2 0 PhoU domain HD PF01966.22 KFX90393.1 - 1.2e-06 28.8 2.8 2.8e-06 27.6 0.3 2.6 3 0 0 3 3 3 1 HD domain Carboxyl_trans PF01039.22 KFX90394.1 - 3e-75 253.8 0.0 3.8e-75 253.4 0.0 1.0 1 0 0 1 1 1 1 Carboxyl transferase domain CPSase_L_D2 PF02786.17 KFX90395.1 - 4.7e-55 186.4 0.0 6.4e-55 185.9 0.0 1.2 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_C PF02785.19 KFX90395.1 - 3.6e-30 104.2 0.0 6.1e-30 103.5 0.0 1.4 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain Biotin_carb_N PF00289.22 KFX90395.1 - 6.2e-27 94.3 0.0 1.1e-26 93.5 0.0 1.4 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_lipoyl PF00364.22 KFX90395.1 - 1.1e-10 41.2 1.5 6.8e-10 38.6 1.6 2.3 3 0 0 3 3 3 1 Biotin-requiring enzyme Dala_Dala_lig_C PF07478.13 KFX90395.1 - 0.00013 21.6 0.0 0.00023 20.8 0.0 1.3 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.22 KFX90395.1 - 0.0008 19.0 0.0 0.0018 17.9 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_3 PF02655.14 KFX90395.1 - 0.0019 18.3 0.0 0.0049 16.9 0.0 1.7 1 1 0 1 1 1 1 ATP-grasp domain Biotin_lipoyl_2 PF13533.6 KFX90395.1 - 0.0023 17.7 0.1 0.0051 16.6 0.1 1.6 1 0 0 1 1 1 1 Biotin-lipoyl like ATPgrasp_ST PF14397.6 KFX90395.1 - 0.0044 16.3 0.0 0.009 15.3 0.0 1.4 1 0 0 1 1 1 1 Sugar-transfer associated ATP-grasp DUF2118 PF09891.9 KFX90395.1 - 0.0065 16.4 0.1 0.012 15.5 0.1 1.4 1 0 0 1 1 1 1 Uncharacterized protein conserved in archaea (DUF2118) RnfC_N PF13375.6 KFX90395.1 - 0.035 14.1 0.0 0.076 13.0 0.0 1.5 1 0 0 1 1 1 0 RnfC Barrel sandwich hybrid domain ATPgrasp_Ter PF15632.6 KFX90395.1 - 0.052 13.3 0.1 0.13 12.0 0.0 1.6 2 0 0 2 2 2 0 ATP-grasp in the biosynthetic pathway with Ter operon ProQ_C PF17516.2 KFX90395.1 - 0.12 11.9 0.5 14 5.2 0.0 2.4 2 0 0 2 2 2 0 ProQ C-terminal domain PDEase_I PF00233.19 KFX90397.1 - 9.8e-67 225.1 1.6 1.2e-61 208.5 0.0 2.3 2 0 0 2 2 2 2 3'5'-cyclic nucleotide phosphodiesterase ClpS PF02617.17 KFX90397.1 - 0.0095 15.7 0.3 5.8 6.8 0.0 2.6 2 0 0 2 2 2 2 ATP-dependent Clp protease adaptor protein ClpS Head-tail_con PF12236.8 KFX90397.1 - 0.068 11.6 0.0 0.11 10.9 0.0 1.2 1 0 0 1 1 1 0 Bacteriophage head to tail connecting protein DUF3535 PF12054.8 KFX90403.1 - 4.8e-126 421.5 4.9 1.5e-124 416.6 3.2 3.1 3 0 0 3 3 3 1 Domain of unknown function (DUF3535) SNF2_N PF00176.23 KFX90403.1 - 6e-64 216.0 0.0 1.5e-63 214.7 0.0 1.6 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KFX90403.1 - 2.9e-19 69.4 0.0 7.2e-19 68.2 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HEAT PF02985.22 KFX90403.1 - 2.5e-17 61.5 15.1 0.052 13.8 0.0 10.1 10 0 0 10 10 9 6 HEAT repeat Vac14_Fab1_bd PF12755.7 KFX90403.1 - 6.3e-08 33.1 0.2 0.36 11.4 0.0 4.1 2 1 1 3 3 3 3 Vacuolar 14 Fab1-binding region HEAT_2 PF13646.6 KFX90403.1 - 8.4e-06 26.1 16.0 0.0021 18.4 0.1 7.4 8 1 0 8 8 8 1 HEAT repeats CLASP_N PF12348.8 KFX90403.1 - 7.7e-05 22.4 0.0 0.13 11.8 0.0 3.3 3 1 1 4 4 4 2 CLASP N terminal IFRD PF05004.13 KFX90403.1 - 0.015 14.4 2.7 0.72 8.9 0.2 4.0 4 0 0 4 4 4 0 Interferon-related developmental regulator (IFRD) TIP120 PF08623.10 KFX90403.1 - 0.016 15.0 0.8 3.1 7.5 0.0 3.2 3 0 0 3 3 3 0 TATA-binding protein interacting (TIP20) TAF6_C PF07571.13 KFX90403.1 - 0.11 12.9 0.0 23 5.4 0.0 4.3 4 1 1 5 5 5 0 TAF6 C-terminal HEAT repeat domain ERCC3_RAD25_C PF16203.5 KFX90403.1 - 0.17 11.0 0.0 0.31 10.2 0.0 1.3 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase Fungal_trans PF04082.18 KFX90405.1 - 5.1e-17 61.8 0.0 9.3e-17 60.9 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KFX90405.1 - 0.00029 20.9 8.6 0.00059 19.9 8.6 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SurE PF01975.17 KFX90410.1 - 7e-50 169.5 0.0 1e-49 169.0 0.0 1.2 1 0 0 1 1 1 1 Survival protein SurE TTL PF03133.15 KFX90410.1 - 7.4e-27 94.2 0.0 1.1e-26 93.6 0.0 1.3 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family YbgS PF13985.6 KFX90412.1 - 0.1 12.9 1.1 0.29 11.4 1.1 1.7 1 0 0 1 1 1 0 YbgS-like protein DUF3425 PF11905.8 KFX90419.1 - 5.9e-12 45.6 0.1 1.1e-11 44.8 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) NmrA PF05368.13 KFX90420.1 - 1.6e-34 119.5 0.1 8.9e-34 117.1 0.1 1.8 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KFX90420.1 - 2.9e-10 40.3 0.1 5.4e-10 39.5 0.1 1.4 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KFX90420.1 - 6.8e-05 22.4 0.0 0.00012 21.7 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family TrkA_N PF02254.18 KFX90420.1 - 0.0027 17.9 0.0 0.0066 16.7 0.0 1.7 1 1 0 1 1 1 1 TrkA-N domain 3Beta_HSD PF01073.19 KFX90420.1 - 0.0044 16.1 0.0 0.0067 15.5 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Semialdhyde_dh PF01118.24 KFX90420.1 - 0.064 13.7 0.0 0.15 12.5 0.0 1.7 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain 3-dmu-9_3-mt PF06983.13 KFX90421.1 - 2.9e-44 150.3 0.3 3.8e-44 149.9 0.3 1.2 1 0 0 1 1 1 1 3-demethylubiquinone-9 3-methyltransferase Glyoxalase PF00903.25 KFX90421.1 - 0.0054 16.9 0.0 0.0069 16.6 0.0 1.3 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Cbl_N2 PF02761.14 KFX90421.1 - 0.11 13.2 0.0 1.7 9.4 0.0 2.2 2 0 0 2 2 2 0 CBL proto-oncogene N-terminus, EF hand-like domain Helo_like_N PF17111.5 KFX90422.1 - 1.9e-06 27.4 3.1 3.8e-06 26.4 0.6 2.3 2 0 0 2 2 2 1 Fungal N-terminal domain of STAND proteins IFT20 PF14931.6 KFX90422.1 - 0.94 9.7 5.6 1.1 9.4 0.6 3.2 2 1 1 3 3 3 0 Intraflagellar transport complex B, subunit 20 DUF1691 PF07950.11 KFX90424.1 - 3.8e-09 37.2 0.2 0.0006 20.5 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF1691) zf-C2H2_jaz PF12171.8 KFX90425.1 - 8.6e-05 22.7 0.8 0.00015 21.9 0.8 1.4 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KFX90425.1 - 0.0032 17.8 0.1 0.0057 17.0 0.1 1.4 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-DBF PF07535.12 KFX90425.1 - 0.0044 17.1 1.7 0.0078 16.3 1.7 1.4 1 0 0 1 1 1 1 DBF zinc finger zf-C2H2 PF00096.26 KFX90425.1 - 0.056 13.9 0.5 0.095 13.2 0.5 1.4 1 0 0 1 1 1 0 Zinc finger, C2H2 type MFS_1 PF07690.16 KFX90426.1 - 1.1e-33 116.7 51.2 1.1e-33 116.7 51.2 1.8 2 1 0 2 2 2 1 Major Facilitator Superfamily DUF4407 PF14362.6 KFX90427.1 - 0.12 11.7 11.2 0.021 14.2 7.4 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) LPD5 PF18799.1 KFX90427.1 - 0.13 12.6 2.7 0.58 10.6 2.7 2.0 1 1 0 1 1 1 0 Large polyvalent protein-associated domain 5 ZapB PF06005.12 KFX90427.1 - 0.15 12.5 20.0 2.4 8.7 2.6 3.3 2 1 1 3 3 3 0 Cell division protein ZapB Rootletin PF15035.6 KFX90427.1 - 0.66 10.0 22.0 0.21 11.6 0.6 2.9 1 1 1 2 2 2 0 Ciliary rootlet component, centrosome cohesion HALZ PF02183.18 KFX90427.1 - 0.67 10.2 6.7 15 5.9 2.3 3.3 2 1 0 2 2 2 0 Homeobox associated leucine zipper HIP1_clath_bdg PF16515.5 KFX90427.1 - 5 7.8 20.6 2.3 8.9 5.7 3.1 1 1 2 3 3 3 0 Clathrin-binding domain of Huntingtin-interacting protein 1 DUF641 PF04859.12 KFX90427.1 - 6.8 7.0 15.8 1.9 8.9 1.1 3.1 1 1 1 3 3 3 0 Plant protein of unknown function (DUF641) DUF3464 PF11947.8 KFX90431.1 - 3 7.6 5.1 4.6 7.0 5.1 1.3 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 zf-FCS PF06467.14 KFX90432.1 - 0.12 12.3 2.0 0.31 11.0 2.0 1.7 1 0 0 1 1 1 0 MYM-type Zinc finger with FCS sequence motif DUF4050 PF13259.6 KFX90434.1 - 2.1e-37 129.2 2.9 9e-36 123.9 2.9 2.1 1 1 0 1 1 1 1 Protein of unknown function (DUF4050) Spike_rec_bind PF09408.10 KFX90434.1 - 0.18 11.5 0.0 0.23 11.2 0.0 1.1 1 0 0 1 1 1 0 Spike receptor binding domain AAA PF00004.29 KFX90435.1 - 4.4e-39 133.9 0.0 1.9e-38 131.9 0.0 2.1 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KFX90435.1 - 2.9e-07 30.2 0.8 2.9e-07 30.2 0.8 2.1 2 0 0 2 2 2 1 AAA+ lid domain RuvB_N PF05496.12 KFX90435.1 - 2.6e-06 27.3 0.6 0.00014 21.7 0.0 2.9 3 0 0 3 3 3 1 Holliday junction DNA helicase RuvB P-loop domain TIP49 PF06068.13 KFX90435.1 - 7.8e-06 25.3 0.3 0.00036 19.8 0.0 2.3 2 0 0 2 2 2 1 TIP49 P-loop domain ABC_tran PF00005.27 KFX90435.1 - 2.4e-05 24.9 0.1 0.22 12.0 0.0 3.9 4 0 0 4 4 4 1 ABC transporter AAA_18 PF13238.6 KFX90435.1 - 2.7e-05 24.7 0.2 0.0039 17.7 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.6 KFX90435.1 - 0.0001 22.6 0.0 0.00082 19.6 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 KFX90435.1 - 0.00015 22.0 1.2 0.0092 16.3 0.1 3.4 2 2 0 2 2 2 1 AAA domain AAA_16 PF13191.6 KFX90435.1 - 0.00015 22.2 1.6 0.00074 19.9 0.1 3.1 3 1 0 3 3 2 1 AAA ATPase domain AAA_33 PF13671.6 KFX90435.1 - 0.00025 21.3 0.1 0.0026 17.9 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_2 PF07724.14 KFX90435.1 - 0.0003 20.9 0.0 0.0083 16.3 0.0 2.6 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 KFX90435.1 - 0.00031 20.7 0.0 0.00097 19.1 0.0 1.9 2 0 0 2 2 1 1 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.17 KFX90435.1 - 0.00051 19.8 0.0 0.011 15.5 0.0 2.4 2 0 0 2 2 2 1 IstB-like ATP binding protein Mg_chelatase PF01078.21 KFX90435.1 - 0.0009 18.7 0.1 0.0049 16.3 0.0 2.0 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_14 PF13173.6 KFX90435.1 - 0.0013 18.7 0.0 0.012 15.7 0.0 2.5 2 1 1 3 3 3 1 AAA domain AAA_24 PF13479.6 KFX90435.1 - 0.0024 17.6 0.0 0.012 15.3 0.0 2.1 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 KFX90435.1 - 0.0027 18.1 0.0 0.014 15.8 0.0 2.2 2 0 0 2 2 2 1 RNA helicase AAA_7 PF12775.7 KFX90435.1 - 0.0045 16.5 0.4 0.096 12.2 0.0 2.7 2 1 0 2 2 2 1 P-loop containing dynein motor region TniB PF05621.11 KFX90435.1 - 0.0085 15.5 0.0 0.24 10.8 0.0 2.9 3 1 0 3 3 3 1 Bacterial TniB protein Parvo_NS1 PF01057.17 KFX90435.1 - 0.01 14.9 0.0 0.017 14.2 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 NACHT PF05729.12 KFX90435.1 - 0.025 14.5 0.1 0.15 11.9 0.0 2.2 2 0 0 2 2 2 0 NACHT domain AAA_17 PF13207.6 KFX90435.1 - 0.033 14.6 0.0 0.11 12.9 0.0 2.0 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 KFX90435.1 - 0.058 13.4 0.0 0.17 11.9 0.0 1.7 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE DUF815 PF05673.13 KFX90435.1 - 0.06 12.5 0.0 0.12 11.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Sigma54_activat PF00158.26 KFX90435.1 - 0.11 12.2 0.1 0.36 10.5 0.0 1.8 2 0 0 2 2 2 0 Sigma-54 interaction domain Sigma54_activ_2 PF14532.6 KFX90435.1 - 0.12 12.5 0.0 0.27 11.3 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain zf-AN1 PF01428.16 KFX90437.1 - 9.9e-13 48.0 6.5 9.9e-13 48.0 6.5 1.5 1 1 0 1 1 1 1 AN1-like Zinc finger Transp_Tc5_C PF04236.15 KFX90437.1 - 0.87 10.0 7.0 0.38 11.2 4.9 1.5 2 0 0 2 2 2 0 Tc5 transposase C-terminal domain Glyco_hydro_18 PF00704.28 KFX90450.1 - 5.1e-63 213.7 0.0 6.2e-63 213.4 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 zf-CCCH PF00642.24 KFX90451.1 - 3.1e-19 68.4 35.6 9.5e-07 28.6 0.7 5.5 4 1 1 5 5 5 5 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 KFX90451.1 - 1.3e-17 63.2 33.2 1.5e-05 24.9 3.7 5.4 5 0 0 5 5 5 5 Zinc finger domain Torus PF16131.5 KFX90451.1 - 1.4e-09 38.6 28.7 0.00043 20.9 1.1 5.6 1 1 4 5 5 5 5 Torus domain zf-CCCH_4 PF18044.1 KFX90451.1 - 7.3e-08 32.0 31.6 2.2e-05 24.1 1.4 5.1 5 0 0 5 5 5 4 CCCH-type zinc finger zf-CCCH_3 PF15663.5 KFX90451.1 - 0.17 12.1 16.0 0.069 13.4 6.8 2.8 1 1 1 2 2 2 0 Zinc-finger containing family ADK PF00406.22 KFX90452.1 - 5.6e-15 55.7 0.0 7.9e-15 55.3 0.0 1.3 1 0 0 1 1 1 1 Adenylate kinase ADK_lid PF05191.14 KFX90452.1 - 7.1e-12 45.1 0.0 1.8e-11 43.8 0.0 1.7 2 0 0 2 2 2 1 Adenylate kinase, active site lid AAA_17 PF13207.6 KFX90452.1 - 0.02 15.4 0.0 0.042 14.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain Pkinase PF00069.25 KFX90457.1 - 3.9e-60 203.4 0.0 5.9e-60 202.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFX90457.1 - 7.6e-30 104.0 0.0 1.1e-29 103.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KFX90457.1 - 0.00067 19.0 0.0 0.0012 18.3 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 KFX90457.1 - 0.0026 17.1 0.2 0.0051 16.2 0.2 1.5 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KFX90457.1 - 0.011 15.7 0.0 0.028 14.3 0.0 1.7 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KFX90457.1 - 0.11 11.3 0.0 0.15 10.8 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase Haspin_kinase PF12330.8 KFX90457.1 - 0.14 11.1 0.1 0.22 10.4 0.1 1.3 1 0 0 1 1 1 0 Haspin like kinase domain A1_Propeptide PF07966.12 KFX90457.1 - 0.16 11.9 0.3 0.31 11.0 0.3 1.4 1 0 0 1 1 1 0 A1 Propeptide Ribosomal_L33 PF00471.20 KFX90459.1 - 6.4e-05 23.3 0.0 9.8e-05 22.7 0.0 1.4 1 1 0 1 1 1 1 Ribosomal protein L33 UPF0242 PF06785.11 KFX90460.1 - 0.0013 18.9 13.7 0.0013 18.9 13.7 6.4 3 2 3 6 6 6 3 Uncharacterised protein family (UPF0242) N-terminus IL31 PF15209.6 KFX90460.1 - 0.072 12.9 1.3 0.28 11.0 1.3 2.1 1 0 0 1 1 1 0 Interleukin 31 Sec8_exocyst PF04048.14 KFX90460.1 - 9.1 6.2 38.5 0.012 15.5 2.6 6.5 4 2 1 6 6 6 0 Sec8 exocyst complex component specific domain RRM_1 PF00076.22 KFX90486.1 - 0.00073 19.3 0.0 0.0017 18.1 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Jnk-SapK_ap_N PF09744.9 KFX90486.1 - 0.013 15.7 3.0 0.04 14.1 3.0 1.8 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 Cullin PF00888.22 KFX90486.1 - 0.036 12.7 0.7 0.058 12.0 0.7 1.2 1 0 0 1 1 1 0 Cullin family MutS_V PF00488.21 KFX90489.1 - 2.5e-66 223.3 0.2 4.3e-66 222.5 0.2 1.4 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 KFX90489.1 - 5.8e-40 137.6 0.0 1.2e-39 136.5 0.0 1.6 1 0 0 1 1 1 1 MutS domain III MutS_I PF01624.20 KFX90489.1 - 2.4e-32 111.5 0.3 7.2e-32 110.0 0.1 2.0 2 0 0 2 2 2 1 MutS domain I MutS_IV PF05190.18 KFX90489.1 - 1.4e-15 57.4 0.1 2.9e-15 56.4 0.1 1.6 1 0 0 1 1 1 1 MutS family domain IV MutS_II PF05188.17 KFX90489.1 - 8.1e-12 45.6 0.0 2.2e-11 44.2 0.0 1.7 1 1 0 1 1 1 1 MutS domain II AAA_23 PF13476.6 KFX90489.1 - 0.00046 20.7 0.1 0.0012 19.4 0.1 1.6 1 0 0 1 1 1 1 AAA domain AAA_27 PF13514.6 KFX90489.1 - 0.046 13.3 0.0 0.1 12.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 KFX90489.1 - 0.065 13.0 0.1 0.14 11.9 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_21 PF13304.6 KFX90489.1 - 0.15 11.8 3.0 0.11 12.3 0.2 2.1 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system WD40 PF00400.32 KFX90490.1 - 2.6e-20 72.3 9.7 0.0016 19.3 0.0 6.4 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFX90490.1 - 2.6e-16 59.7 0.0 4e-06 27.0 0.0 5.3 3 2 2 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KFX90490.1 - 1.9e-05 24.6 0.2 0.025 14.5 0.0 3.0 3 0 0 3 3 3 2 Eukaryotic translation initiation factor eIF2A WD40_like PF17005.5 KFX90490.1 - 0.0013 18.1 0.0 0.65 9.3 0.0 2.3 2 0 0 2 2 2 2 WD40-like domain Ge1_WD40 PF16529.5 KFX90490.1 - 0.0061 15.6 0.0 14 4.5 0.0 3.9 2 1 2 4 4 4 1 WD40 region of Ge1, enhancer of mRNA-decapping protein DPPIV_N PF00930.21 KFX90490.1 - 0.025 13.3 0.0 24 3.6 0.0 3.3 2 1 1 3 3 3 0 Dipeptidyl peptidase IV (DPP IV) N-terminal region PD40 PF07676.12 KFX90490.1 - 0.031 14.2 1.7 15 5.7 0.1 3.5 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat HIRA_B PF09453.10 KFX90490.1 - 0.23 11.4 0.9 0.58 10.1 0.1 2.2 2 0 0 2 2 2 0 HIRA B motif ATP-grasp_2 PF08442.10 KFX90493.1 - 3.7e-78 261.7 0.7 6.6e-78 260.9 0.7 1.4 1 0 0 1 1 1 1 ATP-grasp domain Ligase_CoA PF00549.19 KFX90493.1 - 1.2e-26 93.4 0.3 3.5e-26 91.9 0.3 1.8 1 0 0 1 1 1 1 CoA-ligase ATP-grasp_5 PF13549.6 KFX90493.1 - 2.7e-10 40.1 0.3 5.3e-10 39.1 0.3 1.4 1 0 0 1 1 1 1 ATP-grasp domain GARS_A PF01071.19 KFX90493.1 - 0.0014 18.5 0.9 0.023 14.4 0.2 2.6 2 1 0 2 2 2 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain Ribosomal_S11 PF00411.19 KFX90493.1 - 0.077 13.4 0.8 24 5.4 0.0 3.3 3 0 0 3 3 3 0 Ribosomal protein S11 DUF3245 PF11595.8 KFX90494.1 - 4.7e-12 46.6 7.4 4.7e-12 46.6 7.4 3.4 2 1 1 3 3 3 2 Protein of unknown function (DUF3245) HSF_DNA-bind PF00447.17 KFX90495.1 - 4.3e-30 104.2 0.5 6.7e-30 103.6 0.5 1.3 1 0 0 1 1 1 1 HSF-type DNA-binding LXG PF04740.12 KFX90495.1 - 0.056 13.1 0.2 0.13 12.0 0.1 1.6 2 0 0 2 2 2 0 LXG domain of WXG superfamily Ets PF00178.22 KFX90495.1 - 0.14 12.6 0.0 0.3 11.6 0.0 1.5 1 0 0 1 1 1 0 Ets-domain F-box-like PF12937.7 KFX90497.1 - 0.015 15.2 0.9 0.028 14.3 0.1 1.9 2 0 0 2 2 2 0 F-box-like GrpB PF04229.14 KFX90498.1 - 1.5e-44 152.0 0.1 1.7e-44 151.8 0.1 1.0 1 0 0 1 1 1 1 GrpB protein Epimerase PF01370.21 KFX90499.1 - 2.3e-15 56.7 0.0 3.4e-15 56.2 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 KFX90499.1 - 3.5e-12 46.0 0.0 6.4e-06 25.5 0.0 2.1 2 0 0 2 2 2 2 Male sterility protein 3Beta_HSD PF01073.19 KFX90499.1 - 1.4e-10 40.6 0.0 2.6e-10 39.8 0.0 1.4 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 KFX90499.1 - 8.6e-09 35.2 0.1 3.8e-08 33.1 0.1 1.9 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.6 KFX90499.1 - 3.7e-07 30.2 0.0 6.2e-07 29.5 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding KR PF08659.10 KFX90499.1 - 4.5e-05 23.4 0.0 7.1e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 KR domain F420_oxidored PF03807.17 KFX90499.1 - 0.0015 19.1 0.0 0.0074 16.8 0.0 2.0 1 1 1 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent NmrA PF05368.13 KFX90499.1 - 0.0017 18.0 0.0 0.017 14.7 0.0 2.1 2 0 0 2 2 2 1 NmrA-like family adh_short PF00106.25 KFX90499.1 - 0.0018 17.8 0.0 0.0051 16.3 0.1 1.7 2 0 0 2 2 2 1 short chain dehydrogenase Polysacc_synt_2 PF02719.15 KFX90499.1 - 0.0032 16.6 0.0 0.0045 16.2 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 KFX90499.1 - 0.02 14.0 0.0 0.042 12.9 0.0 1.8 1 1 0 1 1 1 0 RmlD substrate binding domain bZIP_1 PF00170.21 KFX90507.1 - 4e-08 33.2 7.3 4e-08 33.2 7.3 2.3 2 0 0 2 2 2 1 bZIP transcription factor bZIP_Maf PF03131.17 KFX90507.1 - 7.3e-07 29.6 10.1 7.3e-07 29.6 10.1 2.1 2 0 0 2 2 2 1 bZIP Maf transcription factor bZIP_2 PF07716.15 KFX90507.1 - 7.8e-06 25.9 9.1 7.8e-06 25.9 9.1 2.0 2 0 0 2 2 2 1 Basic region leucine zipper YjcZ PF13990.6 KFX90507.1 - 0.67 9.3 7.3 1.5 8.1 7.3 1.5 1 0 0 1 1 1 0 YjcZ-like protein UPF0242 PF06785.11 KFX90507.1 - 7.6 6.6 14.7 13 5.8 14.7 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus BRF1 PF07741.13 KFX90508.1 - 0.066 13.6 0.8 0.16 12.4 0.2 2.0 3 0 0 3 3 3 0 Brf1-like TBP-binding domain Ribosomal_S9 PF00380.19 KFX90509.1 - 8.5e-42 142.5 0.6 1.3e-41 141.9 0.6 1.3 1 0 0 1 1 1 1 Ribosomal protein S9/S16 EF1G PF00647.19 KFX90510.1 - 2.8e-45 152.8 0.1 5.1e-45 151.9 0.1 1.5 1 0 0 1 1 1 1 Elongation factor 1 gamma, conserved domain GST_C PF00043.25 KFX90510.1 - 3.8e-16 59.1 0.1 7.9e-16 58.1 0.1 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 KFX90510.1 - 6.8e-11 42.4 0.0 2.6e-10 40.5 0.0 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KFX90510.1 - 1.4e-10 41.0 0.1 2.8e-10 40.1 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KFX90510.1 - 2.3e-06 27.7 0.1 9.3e-06 25.8 0.0 2.0 1 1 1 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 KFX90510.1 - 0.00047 20.5 0.1 0.0014 19.0 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GET2 PF08690.10 KFX90510.1 - 0.27 10.9 0.4 0.73 9.5 0.0 1.7 2 0 0 2 2 2 0 GET complex subunit GET2 NIF PF03031.18 KFX90511.1 - 1.2e-18 67.4 0.0 1.7e-18 66.8 0.0 1.3 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase RRP36 PF06102.12 KFX90512.1 - 7.8e-54 182.1 29.5 7.8e-54 182.1 29.5 2.2 2 1 0 2 2 2 1 rRNA biogenesis protein RRP36 DUF2383 PF09537.10 KFX90512.1 - 0.0072 16.7 9.5 0.13 12.6 4.6 2.7 2 1 0 2 2 2 2 Domain of unknown function (DUF2383) Es2 PF09751.9 KFX90513.1 - 1.5e-134 450.0 1.7 1.5e-134 450.0 1.7 1.9 2 0 0 2 2 2 1 Nuclear protein Es2 ABC1 PF03109.16 KFX90513.1 - 1.1e-32 112.6 0.0 2.6e-32 111.5 0.0 1.6 1 0 0 1 1 1 1 ABC1 family SIT PF15330.6 KFX90514.1 - 0.12 12.8 0.3 6.1 7.3 0.1 2.1 1 1 1 2 2 2 0 SHP2-interacting transmembrane adaptor protein, SIT Fungal_trans_2 PF11951.8 KFX90516.1 - 1.1e-83 281.2 0.0 4.4e-52 177.2 0.0 2.1 1 1 1 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.18 KFX90516.1 - 2.4e-07 30.8 10.9 4.2e-07 30.0 10.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HMG_CoA_synt_C PF08540.10 KFX90517.1 - 2.2e-103 345.7 0.0 3e-103 345.3 0.0 1.2 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase C terminal HMG_CoA_synt_N PF01154.17 KFX90517.1 - 3.7e-94 313.5 0.4 5.6e-94 312.9 0.4 1.3 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase N terminal DUF3682 PF12446.8 KFX90518.1 - 1.2 9.6 21.3 6.6 7.2 3.0 3.4 2 1 1 3 3 3 0 Protein of unknown function (DUF3682) Pro_CA PF00484.19 KFX90520.1 - 1.5e-50 171.5 0.1 2e-50 171.1 0.1 1.1 1 0 0 1 1 1 1 Carbonic anhydrase PNP_UDP_1 PF01048.20 KFX90520.1 - 0.0083 15.4 0.0 0.011 15.0 0.0 1.1 1 0 0 1 1 1 1 Phosphorylase superfamily TauD PF02668.16 KFX90521.1 - 1e-52 179.6 0.9 1.3e-52 179.3 0.9 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family NTP_transf_9 PF04248.12 KFX90522.1 - 3.2e-29 100.6 1.9 9.5e-26 89.5 0.6 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF427) HTH_17 PF12728.7 KFX90522.1 - 0.016 15.3 0.0 0.065 13.4 0.0 2.1 2 0 0 2 2 2 0 Helix-turn-helix domain TRP PF06011.12 KFX90523.1 - 1.6e-161 537.8 24.9 3e-161 536.9 24.9 1.5 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.6 KFX90523.1 - 8.2e-39 133.1 0.4 1.7e-38 132.1 0.4 1.6 1 0 0 1 1 1 1 ML-like domain MFS_1 PF07690.16 KFX90523.1 - 1.6e-18 66.8 29.4 1.6e-18 66.8 29.4 3.9 3 1 0 3 3 3 1 Major Facilitator Superfamily Ac76 PF05814.11 KFX90523.1 - 0.12 12.4 0.0 0.12 12.4 0.0 2.2 2 0 0 2 2 2 0 Orf76 (Ac76) MitoNEET_N PF10660.9 KFX90523.1 - 5.7 7.0 5.3 2.9 8.0 0.1 3.0 3 0 0 3 3 3 0 Iron-containing outer mitochondrial membrane protein N-terminus Pkinase PF00069.25 KFX90524.1 - 7.7e-06 25.5 0.1 7.7e-05 22.2 0.0 1.9 1 1 1 2 2 2 2 Protein kinase domain Kei1 PF08552.11 KFX90530.1 - 1e-49 169.1 2.1 1.1e-49 168.9 2.1 1.0 1 0 0 1 1 1 1 Inositolphosphorylceramide synthase subunit Kei1 SPC12 PF06645.13 KFX90530.1 - 0.99 9.5 6.9 0.1 12.7 2.4 1.6 2 0 0 2 2 2 0 Microsomal signal peptidase 12 kDa subunit (SPC12) GTP-bdg_M PF16360.5 KFX90531.1 - 0.15 12.7 5.7 0.27 11.9 5.7 1.4 1 0 0 1 1 1 0 GTP-binding GTPase Middle Region G-patch PF01585.23 KFX90532.1 - 1.5e-10 40.8 0.2 3.2e-10 39.7 0.2 1.6 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.7 KFX90532.1 - 0.0039 17.2 0.3 0.0039 17.2 0.3 2.5 2 0 0 2 2 2 1 G-patch domain adh_short PF00106.25 KFX90533.1 - 5.3e-15 55.4 0.0 9.3e-13 48.1 0.0 2.7 3 0 0 3 3 3 2 short chain dehydrogenase adh_short_C2 PF13561.6 KFX90533.1 - 9.8e-08 31.8 0.0 1.3e-06 28.1 0.0 2.3 3 0 0 3 3 3 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KFX90533.1 - 2.1e-07 31.0 0.0 8.8e-07 29.0 0.0 1.9 2 0 0 2 2 2 1 KR domain Epimerase PF01370.21 KFX90533.1 - 3.9e-06 26.5 0.0 7.5e-06 25.6 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF577 PF04510.12 KFX90533.1 - 0.3 11.0 1.9 0.69 9.8 0.8 1.9 2 0 0 2 2 2 0 Family of unknown function (DUF577) SNF2_N PF00176.23 KFX90534.1 - 3.1e-55 187.3 0.1 5.7e-55 186.4 0.1 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KFX90534.1 - 4.2e-14 52.8 0.0 1e-13 51.6 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-RING_UBOX PF13445.6 KFX90534.1 - 1.3e-05 25.1 4.4 3.4e-05 23.8 4.4 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 KFX90534.1 - 2.1e-05 24.3 7.9 4e-05 23.4 7.9 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KFX90534.1 - 2.4e-05 24.1 4.8 4.9e-05 23.1 4.8 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_3 PF13920.6 KFX90534.1 - 2.6e-05 24.0 4.2 2.6e-05 24.0 4.2 1.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KFX90534.1 - 3.1e-05 23.8 7.5 6.1e-05 22.9 7.5 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 KFX90534.1 - 3.5e-05 23.9 7.8 9.4e-05 22.5 7.8 1.8 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.6 KFX90534.1 - 0.00029 21.1 7.0 0.00029 21.1 7.0 1.8 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.6 KFX90534.1 - 0.0012 18.6 9.6 0.0031 17.3 9.6 1.7 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.6 KFX90534.1 - 0.0014 18.4 0.8 0.0031 17.3 0.8 1.5 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-RING_10 PF16685.5 KFX90534.1 - 0.034 14.3 3.1 0.077 13.1 3.1 1.6 1 0 0 1 1 1 0 zinc RING finger of MSL2 FYVE PF01363.21 KFX90534.1 - 0.39 10.9 3.6 0.25 11.5 1.1 2.0 1 1 1 2 2 2 0 FYVE zinc finger zf-rbx1 PF12678.7 KFX90534.1 - 0.49 10.7 4.5 1.1 9.6 4.5 1.6 1 0 0 1 1 1 0 RING-H2 zinc finger domain COesterase PF00135.28 KFX90536.1 - 1.6e-84 284.6 0.0 2.1e-84 284.2 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KFX90536.1 - 1.1e-06 28.7 0.1 3.8e-06 26.9 0.1 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KFX90536.1 - 0.083 12.4 0.0 0.13 11.7 0.0 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family RTA1 PF04479.13 KFX90537.1 - 3e-41 141.3 9.9 3e-41 141.3 9.9 1.4 1 1 0 1 1 1 1 RTA1 like protein DUF5134 PF17197.4 KFX90537.1 - 1.9 8.3 5.4 1.4e+02 2.4 5.4 2.8 1 1 0 1 1 1 0 Domain of unknown function (DUF5134) Amidohydro_1 PF01979.20 KFX90538.1 - 8.7e-15 54.9 0.3 3.9e-14 52.7 0.3 2.0 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 KFX90538.1 - 1.3e-10 41.4 0.5 0.00048 19.7 0.0 2.3 1 1 0 2 2 2 2 Amidohydrolase family Fungal_trans_2 PF11951.8 KFX90538.1 - 0.00025 20.0 2.1 0.0015 17.4 0.4 2.2 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KFX90538.1 - 0.0031 17.6 0.7 0.0061 16.7 0.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Phage_Mu_Gam PF07352.12 KFX90538.1 - 0.18 11.7 0.1 0.59 10.0 0.0 1.8 2 0 0 2 2 2 0 Bacteriophage Mu Gam like protein DUF829 PF05705.14 KFX90539.1 - 4.9e-35 121.6 0.0 6.1e-35 121.3 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF829) BLOC1_2 PF10046.9 KFX90540.1 - 0.14 12.4 1.6 0.35 11.2 1.6 1.6 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Atg14 PF10186.9 KFX90540.1 - 0.26 10.4 4.2 0.41 9.7 4.2 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Ribosomal_60s PF00428.19 KFX90543.1 - 5.9e-26 90.9 9.3 6.8e-26 90.7 9.3 1.0 1 0 0 1 1 1 1 60s Acidic ribosomal protein Ribosomal_S19 PF00203.21 KFX90545.1 - 3e-32 110.4 0.4 4.2e-32 109.9 0.4 1.2 1 0 0 1 1 1 1 Ribosomal protein S19 Thiolase_C PF02803.18 KFX90547.1 - 0.056 13.1 0.0 0.099 12.3 0.0 1.3 1 0 0 1 1 1 0 Thiolase, C-terminal domain AA_permease_2 PF13520.6 KFX90549.1 - 1.9e-53 181.8 53.9 2.4e-53 181.5 53.9 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KFX90549.1 - 2.6e-22 79.1 45.3 3.5e-22 78.7 45.3 1.1 1 0 0 1 1 1 1 Amino acid permease YuiB PF14068.6 KFX90550.1 - 4.7 7.9 14.5 0.099 13.2 5.5 2.6 1 1 2 3 3 3 0 Putative membrane protein Acetyltransf_10 PF13673.7 KFX90551.1 - 1.6e-09 37.8 0.0 5.1e-09 36.2 0.0 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KFX90551.1 - 3e-07 30.8 0.0 7.6e-07 29.5 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KFX90551.1 - 3.6e-07 30.4 0.0 1.1e-06 28.8 0.0 1.9 2 1 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_9 PF13527.7 KFX90551.1 - 0.00027 21.0 0.0 0.028 14.5 0.0 2.5 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 KFX90551.1 - 0.011 15.8 0.0 0.039 14.1 0.0 1.8 2 0 0 2 2 2 0 GCN5-related N-acetyl-transferase FR47 PF08445.10 KFX90551.1 - 0.064 13.2 0.0 0.14 12.1 0.0 1.6 1 0 0 1 1 1 0 FR47-like protein WD40 PF00400.32 KFX90552.1 - 0.1 13.5 0.0 0.7 10.9 0.0 2.2 2 0 0 2 2 2 0 WD domain, G-beta repeat HSP70 PF00012.20 KFX90558.1 - 1.8e-257 855.4 5.0 2.1e-257 855.2 5.0 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 KFX90558.1 - 5.7e-17 61.5 0.0 9.5e-16 57.5 0.0 2.1 2 0 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.16 KFX90558.1 - 0.002 17.9 0.0 0.0051 16.5 0.0 1.6 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FtsA PF14450.6 KFX90558.1 - 0.024 15.1 3.1 10 6.6 0.2 3.4 3 2 0 3 3 3 0 Cell division protein FtsA Hydantoinase_A PF01968.18 KFX90558.1 - 0.03 13.6 0.1 0.07 12.4 0.1 1.6 1 0 0 1 1 1 0 Hydantoinase/oxoprolinase StbA PF06406.11 KFX90558.1 - 0.044 13.0 0.0 0.079 12.2 0.0 1.4 1 0 0 1 1 1 0 StbA protein Mito_carr PF00153.27 KFX90562.1 - 6.6e-65 215.1 6.2 6.9e-23 80.4 0.0 3.2 2 1 1 3 3 3 3 Mitochondrial carrier protein CorA PF01544.18 KFX90563.1 - 0.0016 17.8 0.0 0.0027 17.1 0.0 1.2 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein Mannitol_dh_C PF08125.13 KFX90565.1 - 2.5e-42 145.1 0.0 4.4e-42 144.3 0.0 1.4 1 0 0 1 1 1 1 Mannitol dehydrogenase C-terminal domain Mannitol_dh PF01232.23 KFX90565.1 - 1.3e-22 80.6 0.1 6.9e-22 78.2 0.0 2.2 2 0 0 2 2 2 1 Mannitol dehydrogenase Rossmann domain UDPG_MGDP_dh_N PF03721.14 KFX90565.1 - 0.087 12.4 0.1 0.18 11.4 0.1 1.5 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Myb_DNA-bind_4 PF13837.6 KFX90566.1 - 9e-06 26.0 0.1 1.2e-05 25.6 0.1 1.3 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_5 PF13873.6 KFX90566.1 - 0.018 15.1 0.0 0.035 14.2 0.0 1.5 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain HTH_OrfB_IS605 PF12323.8 KFX90566.1 - 0.13 11.7 0.0 0.21 11.1 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain Pap_E4 PF02711.14 KFX90566.1 - 0.27 12.2 4.5 0.45 11.5 4.5 1.3 1 0 0 1 1 1 0 E4 protein NAM-associated PF14303.6 KFX90566.1 - 0.93 10.2 6.7 1.1 9.9 6.7 1.2 1 0 0 1 1 1 0 No apical meristem-associated C-terminal domain SR-25 PF10500.9 KFX90566.1 - 3.2 7.3 19.9 5 6.7 19.9 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF4614 PF15391.6 KFX90566.1 - 9.4 6.2 9.2 12 5.9 9.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4614) NCBP3 PF10309.9 KFX90567.1 - 3.4e-22 78.1 0.0 5.6e-22 77.4 0.0 1.4 1 0 0 1 1 1 1 Nuclear cap-binding protein subunit 3 TPR_MLP1_2 PF07926.12 KFX90567.1 - 2.6 8.1 20.4 0.041 13.9 12.7 1.9 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein Pec_lyase_C PF00544.19 KFX90568.1 - 7.3e-43 146.6 0.4 1e-42 146.1 0.4 1.1 1 0 0 1 1 1 1 Pectate lyase Beta_helix PF13229.6 KFX90568.1 - 0.0017 18.3 1.8 0.033 14.0 1.8 2.4 1 1 0 1 1 1 1 Right handed beta helix region Beta-lactamase PF00144.24 KFX90569.1 - 7.6e-48 163.4 0.3 4.8e-47 160.8 0.2 1.9 2 0 0 2 2 2 1 Beta-lactamase DUF3471 PF11954.8 KFX90569.1 - 4e-17 62.6 0.0 6.6e-17 61.9 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3471) Imm51 PF15595.6 KFX90569.1 - 0.11 12.5 0.0 0.24 11.4 0.0 1.5 1 0 0 1 1 1 0 Immunity protein 51 WW PF00397.26 KFX90576.1 - 3.5e-11 43.0 6.3 4.3e-11 42.7 6.3 1.1 1 0 0 1 1 1 1 WW domain Glyco_hydro_3 PF00933.21 KFX90587.1 - 2.9e-53 181.3 0.0 3.6e-53 181.0 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain MMR_HSR1_Xtn PF16897.5 KFX90588.1 - 3.6e-39 133.0 0.3 3.6e-39 133.0 0.3 2.3 3 0 0 3 3 3 1 C-terminal region of MMR_HSR1 domain TGS PF02824.21 KFX90588.1 - 3.2e-22 78.3 0.1 7.3e-22 77.2 0.1 1.7 1 0 0 1 1 1 1 TGS domain MMR_HSR1 PF01926.23 KFX90588.1 - 4.4e-22 78.3 0.1 1.8e-21 76.3 0.0 2.0 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 KFX90588.1 - 1.1e-09 38.0 0.0 5.3e-09 35.8 0.0 2.0 2 0 0 2 2 2 1 Ferrous iron transport protein B Dynamin_N PF00350.23 KFX90588.1 - 0.00072 19.7 0.1 0.18 11.8 0.0 2.5 1 1 1 2 2 2 2 Dynamin family GTP_EFTU PF00009.27 KFX90588.1 - 0.0014 18.2 1.3 8.1 5.9 0.0 4.2 3 2 1 4 4 4 2 Elongation factor Tu GTP binding domain MeaB PF03308.16 KFX90588.1 - 0.0087 15.1 0.1 0.02 13.9 0.1 1.6 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB RsgA_GTPase PF03193.16 KFX90588.1 - 0.026 14.5 1.3 2.6 7.9 0.1 3.1 2 1 1 3 3 3 0 RsgA GTPase Arf PF00025.21 KFX90588.1 - 0.048 13.1 0.2 2.8 7.4 0.0 2.3 2 0 0 2 2 2 0 ADP-ribosylation factor family Steroid_dh PF02544.16 KFX90589.1 - 7.4e-10 39.0 0.7 2.8e-09 37.1 0.0 2.2 2 1 0 2 2 2 1 3-oxo-5-alpha-steroid 4-dehydrogenase DUF1295 PF06966.12 KFX90589.1 - 0.0091 15.5 0.4 0.017 14.7 0.4 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF1295) Tmemb_18A PF09771.9 KFX90589.1 - 0.075 13.4 0.0 0.16 12.4 0.0 1.5 1 0 0 1 1 1 0 Transmembrane protein 188 Phage_FRD3 PF05798.11 KFX90589.1 - 0.19 12.1 0.0 0.4 11.0 0.0 1.5 1 0 0 1 1 1 0 Bacteriophage FRD3 protein 2OG-FeII_Oxy_2 PF13532.6 KFX90590.1 - 1e-11 45.4 0.0 1.4e-10 41.7 0.0 2.0 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Peptidase_M3 PF01432.20 KFX90590.1 - 0.068 12.4 0.0 0.091 12.0 0.0 1.1 1 0 0 1 1 1 0 Peptidase family M3 SnoaL_4 PF13577.6 KFX90600.1 - 1.3e-15 57.6 0.1 1.5e-15 57.4 0.1 1.0 1 0 0 1 1 1 1 SnoaL-like domain NAD_binding_10 PF13460.6 KFX90601.1 - 5.2e-14 52.5 2.3 7.4e-14 52.1 2.3 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KFX90601.1 - 4.1e-11 42.8 0.1 1.9e-10 40.7 0.2 1.8 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family NmrA PF05368.13 KFX90601.1 - 1.6e-05 24.6 0.9 2.6e-05 23.9 0.6 1.5 2 0 0 2 2 2 1 NmrA-like family TrkA_N PF02254.18 KFX90601.1 - 8.6e-05 22.8 0.3 0.00015 22.0 0.1 1.6 2 0 0 2 2 2 1 TrkA-N domain F420_oxidored PF03807.17 KFX90601.1 - 0.0016 18.9 0.0 0.0028 18.2 0.0 1.4 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent 3Beta_HSD PF01073.19 KFX90601.1 - 0.0023 17.0 0.0 0.0036 16.4 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 KFX90601.1 - 0.0024 17.0 0.2 0.0032 16.6 0.2 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain GDP_Man_Dehyd PF16363.5 KFX90601.1 - 0.0051 16.3 0.0 0.0069 15.8 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Semialdhyde_dh PF01118.24 KFX90601.1 - 0.0077 16.7 0.1 0.014 15.8 0.1 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Polysacc_synt_2 PF02719.15 KFX90601.1 - 0.0089 15.2 0.1 0.022 13.9 0.1 1.6 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein ADH_zinc_N PF00107.26 KFX90601.1 - 0.0097 15.9 0.3 0.016 15.2 0.3 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Ldh_1_N PF00056.23 KFX90601.1 - 0.024 14.7 0.3 0.037 14.1 0.3 1.2 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain DXP_reductoisom PF02670.16 KFX90601.1 - 0.14 12.9 0.1 0.24 12.1 0.1 1.4 1 0 0 1 1 1 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase NAD_binding_4 PF07993.12 KFX90601.1 - 0.14 11.3 0.1 4.6 6.3 0.0 2.1 1 1 1 2 2 2 0 Male sterility protein Zn_clus PF00172.18 KFX90602.1 - 0.042 14.0 10.3 0.073 13.2 10.3 1.4 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Pollen_allerg_2 PF01620.16 KFX90602.1 - 0.18 12.0 1.2 0.41 10.9 0.7 1.8 2 0 0 2 2 2 0 Ribonuclease (pollen allergen) CybS PF05328.12 KFX90605.1 - 2.7e-49 166.3 0.0 3.5e-49 165.9 0.0 1.1 1 0 0 1 1 1 1 CybS, succinate dehydrogenase cytochrome B small subunit TPPK_C PF12555.8 KFX90605.1 - 0.0045 17.0 0.1 4.3 7.5 0.0 2.4 2 0 0 2 2 2 2 Thiamine pyrophosphokinase C terminal Peptidase_M16 PF00675.20 KFX90606.1 - 5e-56 188.8 0.1 2.8e-55 186.4 0.2 2.1 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 KFX90606.1 - 9.7e-38 130.0 0.0 9.3e-37 126.8 0.0 2.2 2 0 0 2 2 2 1 Peptidase M16 inactive domain SecIII_SopE_N PF05364.14 KFX90606.1 - 0.083 13.0 0.3 23 5.2 0.1 2.6 2 0 0 2 2 2 0 Salmonella type III secretion SopE effector N-terminus MTD PF01993.18 KFX90606.1 - 0.086 12.1 0.0 1.1 8.6 0.1 2.1 1 1 1 2 2 2 0 methylene-5,6,7,8-tetrahydromethanopterin dehydrogenase MFS_1 PF07690.16 KFX90607.1 - 1.2e-37 129.6 57.7 3.9e-30 105.0 42.0 2.7 1 1 1 2 2 2 2 Major Facilitator Superfamily Epiglycanin_C PF14654.6 KFX90607.1 - 0.11 12.5 0.6 0.96 9.5 0.1 2.8 2 0 0 2 2 2 0 Mucin, catalytic, TM and cytoplasmic tail region Abhydrolase_4 PF08386.10 KFX90608.1 - 2.5e-21 75.7 0.0 5.2e-21 74.7 0.0 1.5 1 0 0 1 1 1 1 TAP-like protein Abhydrolase_1 PF00561.20 KFX90608.1 - 3.9e-14 52.9 0.0 9.5e-11 41.8 0.0 3.1 2 1 0 2 2 2 2 alpha/beta hydrolase fold Coa1 PF08695.10 KFX90611.1 - 1.2e-39 134.7 0.0 1.5e-39 134.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome oxidase complex assembly protein 1 RXT2_N PF08595.11 KFX90618.1 - 3.9e-47 160.2 0.2 3.9e-47 160.2 0.2 2.7 2 1 0 2 2 2 1 RXT2-like, N-terminal Chondroitinas_B PF14592.6 KFX90618.1 - 0.066 12.1 0.0 0.088 11.7 0.0 1.1 1 0 0 1 1 1 0 Chondroitinase B zf-C3HC4_3 PF13920.6 KFX90621.1 - 0.0019 18.0 11.5 0.003 17.4 11.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.6 KFX90621.1 - 0.0088 15.9 6.3 0.015 15.2 6.3 1.3 1 0 0 1 1 1 1 zf-RING of BARD1-type protein Abhydrolase_3 PF07859.13 KFX90622.1 - 2.8e-26 92.7 0.0 3.7e-26 92.3 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 KFX90622.1 - 4.4e-19 68.6 0.0 1.1e-18 67.3 0.0 1.6 1 1 0 1 1 1 1 Steryl acetyl hydrolase Peptidase_S9 PF00326.21 KFX90622.1 - 0.0015 18.0 0.0 0.0024 17.4 0.0 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family BAAT_C PF08840.11 KFX90622.1 - 0.076 12.9 0.0 0.12 12.3 0.0 1.2 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal DUF4761 PF15958.5 KFX90623.1 - 0.023 14.8 0.0 0.034 14.3 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4761) TPR_8 PF13181.6 KFX90626.1 - 4.1e-06 26.6 0.6 0.029 14.6 0.0 3.3 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.17 KFX90626.1 - 5.3e-06 26.1 4.1 0.012 15.7 0.2 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 KFX90626.1 - 1.3e-05 25.4 4.4 0.00062 20.0 0.2 3.8 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.6 KFX90626.1 - 9.5e-05 22.8 4.0 0.054 14.1 0.2 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 KFX90626.1 - 0.00028 21.5 1.0 0.033 14.9 0.1 3.6 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 KFX90626.1 - 0.015 15.1 5.8 0.94 9.4 0.1 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_19 PF14559.6 KFX90626.1 - 0.018 15.5 2.2 0.17 12.4 0.3 3.2 3 1 1 4 4 4 0 Tetratricopeptide repeat Terminase_6C PF17289.2 KFX90626.1 - 0.021 15.0 0.1 0.035 14.2 0.1 1.5 1 0 0 1 1 1 0 Terminase RNaseH-like domain TPR_7 PF13176.6 KFX90626.1 - 0.053 13.6 0.6 4 7.7 0.1 3.4 4 0 0 4 4 4 0 Tetratricopeptide repeat ANAPC3 PF12895.7 KFX90626.1 - 0.061 13.6 0.2 0.25 11.6 0.2 2.1 1 1 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 SNAP PF14938.6 KFX90626.1 - 0.086 12.2 5.0 0.41 10.0 5.0 1.9 1 1 0 1 1 1 0 Soluble NSF attachment protein, SNAP TPR_10 PF13374.6 KFX90626.1 - 0.093 12.6 2.3 0.48 10.4 0.1 3.4 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_17 PF13431.6 KFX90626.1 - 0.16 12.4 2.7 1.3 9.5 0.2 3.6 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_11 PF13414.6 KFX90626.1 - 0.17 11.6 3.7 0.29 10.9 0.1 3.1 3 1 0 3 3 3 0 TPR repeat TPR_14 PF13428.6 KFX90626.1 - 0.2 12.6 8.0 1.1 10.3 0.1 4.6 5 0 0 5 5 4 0 Tetratricopeptide repeat U3_snoRNA_assoc PF08297.11 KFX90627.1 - 1.5e-08 35.3 2.8 1.5e-08 35.3 2.8 5.1 3 2 0 3 3 3 1 U3 snoRNA associated ABM PF03992.16 KFX90627.1 - 0.0066 16.5 0.0 0.016 15.3 0.0 1.7 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase CLASP_N PF12348.8 KFX90630.1 - 0.002 17.7 0.0 0.0023 17.5 0.0 1.0 1 0 0 1 1 1 1 CLASP N terminal IBN_N PF03810.19 KFX90630.1 - 0.016 15.1 0.0 0.017 15.0 0.0 1.1 1 0 0 1 1 1 0 Importin-beta N-terminal domain THF_DHG_CYH PF00763.23 KFX90635.1 - 1e-21 77.4 0.0 1.7e-21 76.6 0.0 1.4 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain THF_DHG_CYH_C PF02882.19 KFX90635.1 - 2.7e-15 56.0 0.0 3.1e-09 36.3 0.0 2.5 2 0 0 2 2 2 2 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain ERCC4 PF02732.15 KFX90636.1 - 2e-27 96.3 0.0 3.6e-27 95.5 0.0 1.4 1 0 0 1 1 1 1 ERCC4 domain EMC3_TMCO1 PF01956.16 KFX90637.1 - 1.4e-51 174.7 1.0 2.4e-51 173.9 1.0 1.4 1 0 0 1 1 1 1 Integral membrane protein EMC3/TMCO1-like MscS_TM PF12794.7 KFX90637.1 - 0.036 12.9 0.3 0.058 12.2 0.3 1.2 1 0 0 1 1 1 0 Mechanosensitive ion channel inner membrane domain 1 SAPS PF04499.15 KFX90647.1 - 3.5e-117 392.2 1.3 2.8e-116 389.2 0.0 2.0 2 0 0 2 2 2 2 SIT4 phosphatase-associated protein Snf7 PF03357.21 KFX90649.1 - 3.9e-44 150.3 11.2 4.6e-44 150.1 11.2 1.1 1 0 0 1 1 1 1 Snf7 Alpha-2-MRAP_C PF06401.11 KFX90649.1 - 0.024 14.6 3.7 0.048 13.6 2.5 1.9 1 1 1 2 2 2 0 Alpha-2-macroglobulin RAP, C-terminal domain RE_Bsp6I PF09504.10 KFX90649.1 - 0.024 14.2 0.7 0.059 13.0 0.2 1.8 2 0 0 2 2 2 0 Bsp6I restriction endonuclease NPV_P10 PF05531.12 KFX90649.1 - 0.066 13.7 9.0 1.4 9.5 1.9 2.8 3 1 0 3 3 3 0 Nucleopolyhedrovirus P10 protein FapA PF03961.13 KFX90649.1 - 0.16 10.6 8.0 0.81 8.2 4.9 2.0 1 1 1 2 2 2 0 Flagellar Assembly Protein A FlaC_arch PF05377.11 KFX90649.1 - 2.8 8.4 9.4 5.5 7.5 0.0 3.5 3 1 1 4 4 4 0 Flagella accessory protein C (FlaC) Hist_deacetyl PF00850.19 KFX90652.1 - 9.9e-82 274.8 0.1 1.8e-81 274.0 0.0 1.5 2 0 0 2 2 2 1 Histone deacetylase domain JAB PF01398.21 KFX90653.1 - 2.9e-33 114.3 0.0 5.9e-33 113.4 0.0 1.5 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.6 KFX90653.1 - 2.9e-11 43.8 0.5 5.8e-11 42.8 0.5 1.5 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function Prok-JAB PF14464.6 KFX90653.1 - 1.3e-07 31.4 0.0 2.5e-07 30.5 0.0 1.5 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain PTR2 PF00854.21 KFX90654.1 - 3.2e-76 256.7 9.0 4.4e-76 256.3 9.0 1.2 1 0 0 1 1 1 1 POT family MFS_1 PF07690.16 KFX90654.1 - 1.1e-06 27.8 23.1 3.8e-05 22.8 23.7 2.5 2 1 0 2 2 2 1 Major Facilitator Superfamily Rod_cone_degen PF15201.6 KFX90654.1 - 0.0062 16.6 0.1 0.45 10.6 0.0 2.4 2 0 0 2 2 2 1 Progressive rod-cone degeneration DUF2304 PF10066.9 KFX90654.1 - 2.3 8.5 7.7 11 6.3 0.1 3.4 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2304) PPI_Ypi1 PF07491.11 KFX90660.1 - 0.018 14.9 6.0 0.018 14.9 6.0 2.4 2 1 0 2 2 2 0 Protein phosphatase inhibitor Ribonuc_L-PSP PF01042.21 KFX90661.1 - 9.6e-39 132.1 0.0 1.1e-38 132.0 0.0 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP DDE_Tnp_4 PF13359.6 KFX90661.1 - 0.067 12.9 0.0 0.1 12.3 0.0 1.3 1 1 0 1 1 1 0 DDE superfamily endonuclease Aldo_ket_red PF00248.21 KFX90664.1 - 5.1e-41 140.8 0.0 6.9e-40 137.1 0.0 2.2 1 1 0 1 1 1 1 Aldo/keto reductase family Glyco_hydro_16 PF00722.21 KFX90664.1 - 7.9e-41 139.5 1.3 1.3e-40 138.7 1.3 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Fungal_trans PF04082.18 KFX90664.1 - 8.5e-05 21.7 0.0 0.00018 20.6 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Peptidase_M22 PF00814.25 KFX90671.1 - 5.4e-83 278.8 0.0 6.3e-83 278.6 0.0 1.0 1 0 0 1 1 1 1 Glycoprotease family Carbam_trans_N PF02543.15 KFX90671.1 - 0.021 14.5 0.0 0.66 9.6 0.0 2.2 2 0 0 2 2 2 0 Carbamoyltransferase N-terminus AMPKBI PF04739.15 KFX90672.1 - 1.8e-25 89.0 1.5 1.8e-25 89.0 1.5 2.2 2 0 0 2 2 2 1 5'-AMP-activated protein kinase beta subunit, interaction domain AMPK1_CBM PF16561.5 KFX90672.1 - 1e-23 83.3 0.0 1.8e-23 82.6 0.0 1.4 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase Pribosyl_synth PF14572.6 KFX90672.1 - 0.17 11.9 0.9 0.38 10.8 0.9 1.5 1 0 0 1 1 1 0 Phosphoribosyl synthetase-associated domain DUF3034 PF11231.8 KFX90673.1 - 0.096 12.2 0.0 0.16 11.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3034) Pkinase PF00069.25 KFX90674.1 - 2.3e-60 204.2 0.0 2.9e-60 203.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFX90674.1 - 3.4e-25 88.8 0.0 8.7e-24 84.2 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 KFX90674.1 - 0.007 15.4 0.0 0.012 14.6 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 KFX90674.1 - 0.016 14.5 0.0 0.095 12.0 0.0 2.0 2 1 0 2 2 2 0 Kinase-like Peptidase_C78 PF07910.13 KFX90676.1 - 2.2e-66 223.3 0.0 2.2e-65 220.1 0.0 2.2 1 1 0 1 1 1 1 Peptidase family C78 Ham1p_like PF01725.16 KFX90676.1 - 3e-56 190.3 0.0 4.4e-56 189.8 0.0 1.2 1 0 0 1 1 1 1 Ham1 family zf-Di19 PF05605.12 KFX90676.1 - 0.0091 16.3 0.3 0.29 11.5 0.0 2.5 2 0 0 2 2 2 1 Drought induced 19 protein (Di19), zinc-binding AAA_18 PF13238.6 KFX90677.1 - 8.1e-27 94.3 0.0 1.4e-26 93.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.6 KFX90677.1 - 2.8e-09 37.5 0.0 2.2e-08 34.6 0.0 2.2 1 1 1 2 2 2 1 AAA domain AAA PF00004.29 KFX90677.1 - 7.8e-06 26.3 0.1 0.0006 20.2 0.0 2.2 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) ADK PF00406.22 KFX90677.1 - 0.00014 22.0 0.6 0.005 17.0 0.6 2.4 1 1 0 1 1 1 1 Adenylate kinase AAA_33 PF13671.6 KFX90677.1 - 0.00024 21.3 0.1 0.00064 19.9 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_28 PF13521.6 KFX90677.1 - 0.00036 20.8 0.1 0.00072 19.8 0.0 1.6 2 0 0 2 2 2 1 AAA domain NTPase_1 PF03266.15 KFX90677.1 - 0.00038 20.4 0.0 0.00077 19.4 0.0 1.6 1 0 0 1 1 1 1 NTPase Hydin_ADK PF17213.3 KFX90677.1 - 0.00068 20.0 0.0 0.0013 19.1 0.0 1.5 1 0 0 1 1 1 1 Hydin Adenylate kinase-like domain AAA_22 PF13401.6 KFX90677.1 - 0.00093 19.5 0.4 0.002 18.4 0.1 1.7 2 0 0 2 2 2 1 AAA domain Thymidylate_kin PF02223.17 KFX90677.1 - 0.0016 18.1 0.8 0.51 10.0 0.1 2.2 2 0 0 2 2 2 2 Thymidylate kinase KTI12 PF08433.10 KFX90677.1 - 0.0023 17.4 0.0 0.0056 16.2 0.0 1.6 2 0 0 2 2 2 1 Chromatin associated protein KTI12 RNA_helicase PF00910.22 KFX90677.1 - 0.0093 16.3 0.0 0.017 15.5 0.0 1.5 1 0 0 1 1 1 1 RNA helicase AAA_16 PF13191.6 KFX90677.1 - 0.01 16.2 0.1 0.021 15.2 0.1 1.6 1 1 0 1 1 1 0 AAA ATPase domain FtsK_SpoIIIE PF01580.18 KFX90677.1 - 0.011 15.1 0.2 0.02 14.2 0.2 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_14 PF13173.6 KFX90677.1 - 0.023 14.7 0.0 0.073 13.1 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 KFX90677.1 - 0.033 13.9 0.5 0.078 12.7 0.2 1.8 1 1 0 2 2 2 0 AAA domain dNK PF01712.19 KFX90677.1 - 0.041 13.7 3.5 1.3 8.9 0.2 2.2 1 1 1 2 2 2 0 Deoxynucleoside kinase SKI PF01202.22 KFX90677.1 - 0.055 13.6 1.5 0.83 9.8 1.5 2.1 1 1 0 1 1 1 0 Shikimate kinase ATP_bind_1 PF03029.17 KFX90677.1 - 0.056 13.2 0.2 0.12 12.1 0.2 1.6 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein AAA_3 PF07726.11 KFX90677.1 - 0.059 13.2 0.0 0.1 12.4 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) IstB_IS21 PF01695.17 KFX90677.1 - 0.066 12.9 0.3 0.12 12.1 0.0 1.6 2 0 0 2 2 1 0 IstB-like ATP binding protein AAA_19 PF13245.6 KFX90677.1 - 0.069 13.5 1.0 0.14 12.5 0.4 1.8 2 0 0 2 2 2 0 AAA domain SRP54 PF00448.22 KFX90677.1 - 0.079 12.6 0.1 0.14 11.8 0.1 1.3 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_5 PF07728.14 KFX90677.1 - 0.092 12.7 0.0 0.15 12.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 KFX90677.1 - 0.097 12.4 0.1 0.2 11.4 0.1 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain Cytidylate_kin2 PF13189.6 KFX90677.1 - 0.11 12.7 0.0 0.16 12.1 0.0 1.7 1 1 0 1 1 1 0 Cytidylate kinase-like family MeaB PF03308.16 KFX90677.1 - 0.11 11.4 0.9 0.15 11.0 0.1 1.6 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB T2SSE PF00437.20 KFX90677.1 - 0.14 11.2 1.2 0.21 10.6 0.6 1.6 2 0 0 2 2 2 0 Type II/IV secretion system protein Viral_helicase1 PF01443.18 KFX90677.1 - 0.15 11.8 0.0 0.23 11.2 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_30 PF13604.6 KFX90677.1 - 0.17 11.6 2.1 2.2 7.9 0.6 2.3 1 1 1 2 2 2 0 AAA domain Myosin_head PF00063.21 KFX90678.1 - 8.1e-260 863.7 0.0 1.3e-259 863.1 0.0 1.3 1 0 0 1 1 1 1 Myosin head (motor domain) DIL PF01843.19 KFX90678.1 - 3.4e-26 91.5 2.9 3.4e-26 91.5 2.9 2.4 2 0 0 2 2 2 1 DIL domain IQ PF00612.27 KFX90678.1 - 2.1e-12 45.7 30.6 0.00027 20.5 1.3 6.8 6 0 0 6 6 6 4 IQ calmodulin-binding motif Myosin_N PF02736.19 KFX90678.1 - 0.00011 21.9 0.3 0.00031 20.5 0.3 1.8 1 0 0 1 1 1 1 Myosin N-terminal SH3-like domain AAA_22 PF13401.6 KFX90678.1 - 0.00067 19.9 0.1 0.0035 17.6 0.1 2.3 1 1 0 1 1 1 1 AAA domain KASH_CCD PF14662.6 KFX90678.1 - 0.0013 18.6 6.6 0.0013 18.6 6.6 2.9 1 1 1 2 2 2 1 Coiled-coil region of CCDC155 or KASH GAS PF13851.6 KFX90678.1 - 0.0025 17.2 12.1 0.0025 17.2 12.1 2.9 1 1 1 2 2 2 1 Growth-arrest specific micro-tubule binding Sec34 PF04136.15 KFX90678.1 - 0.0056 16.6 3.7 0.021 14.7 3.7 2.1 1 0 0 1 1 1 1 Sec34-like family AAA_16 PF13191.6 KFX90678.1 - 0.006 17.0 0.0 0.044 14.2 0.0 2.6 2 0 0 2 2 2 1 AAA ATPase domain RNA_helicase PF00910.22 KFX90678.1 - 0.16 12.4 0.1 0.81 10.1 0.0 2.3 2 0 0 2 2 2 0 RNA helicase Baculo_PEP_C PF04513.12 KFX90678.1 - 0.36 10.9 4.4 2.8 8.0 4.4 2.7 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus FlaC_arch PF05377.11 KFX90678.1 - 1 9.8 8.7 0.28 11.6 0.4 3.8 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) MbeD_MobD PF04899.12 KFX90678.1 - 1.1 9.4 4.8 22 5.2 0.2 3.5 3 0 0 3 3 3 0 MbeD/MobD like ABC_tran PF00005.27 KFX90678.1 - 3.4 8.2 8.2 3.3 8.2 0.0 4.2 4 1 0 4 4 3 0 ABC transporter DegQ PF08181.11 KFX90678.1 - 5.4 7.2 7.6 0.44 10.7 1.2 2.7 2 0 0 2 2 1 0 DegQ (SacQ) family ArgJ PF01960.18 KFX90679.1 - 1.3e-150 501.3 0.5 1.5e-150 501.1 0.5 1.0 1 0 0 1 1 1 1 ArgJ family A_deamin PF02137.18 KFX90679.1 - 0.17 11.3 0.0 0.27 10.6 0.0 1.3 1 0 0 1 1 1 0 Adenosine-deaminase (editase) domain ORC2 PF04084.14 KFX90680.1 - 6.4e-124 413.2 0.0 7.8e-124 412.9 0.0 1.1 1 0 0 1 1 1 1 Origin recognition complex subunit 2 ATP19 PF11022.8 KFX90680.1 - 0.2 12.0 0.1 0.57 10.6 0.1 1.8 1 0 0 1 1 1 0 ATP synthase subunit K AT_hook PF02178.19 KFX90680.1 - 0.32 11.0 19.1 1.2 9.3 3.8 3.1 2 0 0 2 2 2 0 AT hook motif zf-PARP PF00645.18 KFX90681.1 - 0.0031 18.4 0.0 0.0065 17.3 0.0 1.6 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region DUF410 PF04190.13 KFX90682.1 - 5.7e-93 311.4 0.0 7.6e-93 311.0 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF410) fn3 PF00041.21 KFX90700.1 - 2.5e-07 30.9 0.0 8e-07 29.3 0.0 1.9 1 0 0 1 1 1 1 Fibronectin type III domain HlyD_2 PF12700.7 KFX90700.1 - 7.9 5.1 18.6 11 4.6 18.6 1.2 1 0 0 1 1 1 0 HlyD family secretion protein LNS2 PF08235.13 KFX90701.1 - 4.2e-94 314.2 0.0 5.9e-94 313.8 0.0 1.2 1 0 0 1 1 1 1 LNS2 (Lipin/Ned1/Smp2) Lipin_N PF04571.14 KFX90701.1 - 6.7e-43 144.8 0.0 1.4e-42 143.8 0.0 1.6 1 0 0 1 1 1 1 lipin, N-terminal conserved region Acid_phosphat_B PF03767.14 KFX90701.1 - 0.12 12.0 0.0 0.56 9.8 0.0 2.0 2 0 0 2 2 2 0 HAD superfamily, subfamily IIIB (Acid phosphatase) Peptidase_M49 PF03571.15 KFX90702.1 - 6.5e-233 774.1 0.0 7.7e-233 773.8 0.0 1.0 1 0 0 1 1 1 1 Peptidase family M49 Glucosamine_iso PF01182.20 KFX90702.1 - 0.048 13.5 0.0 0.08 12.8 0.0 1.3 1 0 0 1 1 1 0 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase CdiA_C_tRNase PF18664.1 KFX90702.1 - 0.12 12.6 0.1 0.74 10.0 0.0 2.1 2 0 0 2 2 2 0 CdiA C-terminal tRNase domain OmdA PF13376.6 KFX90702.1 - 0.41 10.7 2.1 5.7 7.0 0.1 2.5 2 0 0 2 2 2 0 Bacteriocin-protection, YdeI or OmpD-Associated 4HBT_3 PF13622.6 KFX90703.1 - 7.1e-40 137.8 0.0 1e-39 137.3 0.0 1.2 1 0 0 1 1 1 1 Thioesterase-like superfamily MFS_1 PF07690.16 KFX90703.1 - 1.1e-31 110.1 29.0 1.1e-31 110.1 29.0 2.1 2 1 0 2 2 2 1 Major Facilitator Superfamily 4HBT PF03061.22 KFX90703.1 - 0.0003 21.1 0.0 0.0022 18.3 0.0 2.2 2 0 0 2 2 2 1 Thioesterase superfamily TMEM237 PF15383.6 KFX90703.1 - 0.17 11.0 0.8 1.3 8.0 0.2 2.4 2 0 0 2 2 2 0 Transmembrane protein 237 Zn_clus PF00172.18 KFX90704.1 - 1.5e-06 28.2 8.4 3e-06 27.3 8.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PEP_mutase PF13714.6 KFX90705.1 - 9.4e-46 156.2 0.3 1.3e-45 155.8 0.3 1.2 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase MaoC_dehydratas PF01575.19 KFX90705.1 - 6e-22 77.5 0.0 1.1e-21 76.7 0.0 1.4 1 0 0 1 1 1 1 MaoC like domain ICL PF00463.21 KFX90705.1 - 7.2e-20 71.0 0.1 1.1e-19 70.4 0.1 1.1 1 0 0 1 1 1 1 Isocitrate lyase family Transglut_core2 PF13369.6 KFX90709.1 - 0.15 11.6 0.0 0.26 10.8 0.0 1.3 1 0 0 1 1 1 0 Transglutaminase-like superfamily Aminotran_1_2 PF00155.21 KFX90713.1 - 5.1e-25 88.4 0.0 7.8e-25 87.8 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Abhydrolase_1 PF00561.20 KFX90713.1 - 2.1e-09 37.4 0.0 3.4e-09 36.7 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KFX90713.1 - 4.3e-08 34.0 0.1 1.6e-07 32.2 0.0 2.0 2 1 1 3 3 3 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KFX90713.1 - 6.7e-05 22.3 0.0 0.00013 21.3 0.0 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 OKR_DC_1 PF01276.20 KFX90713.1 - 0.25 10.0 0.0 12 4.5 0.0 2.1 2 0 0 2 2 2 0 Orn/Lys/Arg decarboxylase, major domain Aminotran_3 PF00202.21 KFX90714.1 - 1.1e-39 136.2 0.0 2.2e-19 69.4 0.0 3.0 2 1 0 2 2 2 2 Aminotransferase class-III AAA_26 PF13500.6 KFX90714.1 - 8.6e-18 64.9 0.0 1.3e-17 64.3 0.0 1.3 1 0 0 1 1 1 1 AAA domain p450 PF00067.22 KFX90715.1 - 2.3e-59 201.4 0.0 3.1e-59 201.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Methyltransf_23 PF13489.6 KFX90716.1 - 3.6e-18 65.9 0.0 5.9e-18 65.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KFX90716.1 - 2.1e-10 41.2 0.0 4.9e-10 40.0 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KFX90716.1 - 4.8e-08 33.5 0.0 1e-07 32.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KFX90716.1 - 8.6e-07 28.9 0.0 1.1e-05 25.2 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KFX90716.1 - 1.2e-05 26.0 0.0 5.9e-05 23.7 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.17 KFX90716.1 - 0.015 14.7 0.0 0.026 14.0 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase FtsJ PF01728.19 KFX90716.1 - 0.019 15.0 0.0 0.04 14.0 0.0 1.4 1 0 0 1 1 1 0 FtsJ-like methyltransferase MTS PF05175.14 KFX90716.1 - 0.031 13.8 0.0 0.05 13.1 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_2 PF00891.18 KFX90716.1 - 0.038 13.3 0.0 0.067 12.5 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase domain PrmA PF06325.13 KFX90716.1 - 0.07 12.5 0.0 0.13 11.6 0.0 1.4 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) AA_permease_2 PF13520.6 KFX90736.1 - 2e-36 125.8 34.9 2.6e-36 125.4 34.9 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KFX90736.1 - 9.6e-11 40.9 25.9 1.2e-10 40.6 25.9 1.1 1 0 0 1 1 1 1 Amino acid permease GRP PF07172.11 KFX90737.1 - 0.0059 17.3 8.3 0.0059 17.3 8.3 3.9 2 1 0 2 2 2 1 Glycine rich protein family TFIIA PF03153.13 KFX90737.1 - 0.96 9.4 30.7 0.14 12.2 16.1 2.2 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit EMG1 PF03587.14 KFX90738.1 - 1.3e-78 263.2 0.0 1.5e-78 262.9 0.0 1.0 1 0 0 1 1 1 1 EMG1/NEP1 methyltransferase GPI-anchored PF10342.9 KFX90747.1 - 2.9e-07 31.2 0.0 3.7e-07 30.8 0.0 1.2 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Glyco_hydro_38N PF01074.22 KFX90749.1 - 1.3e-83 280.7 0.8 2.1e-83 280.0 0.8 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 N-terminal domain Glyco_hydro_38C PF07748.13 KFX90749.1 - 6.7e-59 199.5 0.0 1.1e-58 198.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal domain Alpha-mann_mid PF09261.11 KFX90749.1 - 4.1e-28 97.4 0.1 8.3e-28 96.4 0.1 1.6 1 0 0 1 1 1 1 Alpha mannosidase middle domain Glyco_hydro38C2 PF17677.1 KFX90749.1 - 4e-09 36.5 0.0 2.5e-08 33.9 0.0 2.4 2 1 0 2 2 2 1 Glycosyl hydrolases family 38 C-terminal beta sandwich domain Glyco_hydro_57 PF03065.15 KFX90749.1 - 0.055 12.7 0.1 0.12 11.5 0.0 1.6 2 0 0 2 2 2 0 Glycosyl hydrolase family 57 DeoC PF01791.9 KFX90751.1 - 1.5e-12 47.6 1.2 2.4e-12 47.0 1.2 1.3 1 0 0 1 1 1 1 DeoC/LacD family aldolase His_biosynth PF00977.21 KFX90751.1 - 0.018 14.5 0.1 0.032 13.7 0.1 1.4 1 0 0 1 1 1 0 Histidine biosynthesis protein SRF-TF PF00319.18 KFX90753.1 - 7.1e-21 73.4 0.1 1e-20 72.9 0.1 1.2 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) FGGY_C PF02782.16 KFX90757.1 - 1.4e-48 165.3 0.2 2e-48 164.8 0.2 1.2 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.21 KFX90757.1 - 5.3e-23 81.9 0.3 1.2e-20 74.1 0.0 2.5 2 0 0 2 2 2 2 FGGY family of carbohydrate kinases, N-terminal domain Hexokinase_1 PF00349.21 KFX90757.1 - 0.0052 16.7 0.0 0.012 15.6 0.0 1.5 1 0 0 1 1 1 1 Hexokinase BcrAD_BadFG PF01869.20 KFX90757.1 - 0.0055 16.2 0.1 0.037 13.5 0.0 2.1 2 0 0 2 2 2 1 BadF/BadG/BcrA/BcrD ATPase family POR_N PF01855.19 KFX90757.1 - 0.41 10.4 1.6 0.75 9.5 1.6 1.3 1 0 0 1 1 1 0 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg ADH_N PF08240.12 KFX90758.1 - 5.6e-31 106.7 1.6 1.2e-30 105.6 1.6 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KFX90758.1 - 1.7e-24 86.2 0.3 2.8e-24 85.5 0.3 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 KFX90758.1 - 1.4e-10 41.0 0.2 2.3e-10 40.3 0.2 1.3 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus ADH_zinc_N_2 PF13602.6 KFX90758.1 - 6.2e-05 24.1 0.1 0.00031 21.8 0.1 2.1 1 1 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 KFX90758.1 - 0.0096 15.2 1.0 0.016 14.5 1.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox_2 PF07992.14 KFX90758.1 - 0.011 15.0 0.3 0.022 14.0 0.3 1.6 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase UDPG_MGDP_dh_N PF03721.14 KFX90758.1 - 0.011 15.3 0.2 0.019 14.5 0.2 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Methyltransf_25 PF13649.6 KFX90758.1 - 0.037 14.7 0.1 0.19 12.4 0.1 2.1 2 0 0 2 2 2 0 Methyltransferase domain 2-Hacid_dh_C PF02826.19 KFX90758.1 - 0.05 13.0 0.0 0.08 12.3 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NADH_4Fe-4S PF10589.9 KFX90758.1 - 0.12 12.4 1.0 1.3 9.2 1.8 2.1 2 0 0 2 2 2 0 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region Sugar_tr PF00083.24 KFX90759.1 - 1.8e-49 168.9 5.8 2.2e-49 168.5 5.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KFX90759.1 - 2.3e-19 69.5 9.1 2.7e-19 69.3 9.1 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_2 PF13347.6 KFX90759.1 - 0.00068 18.3 5.3 0.095 11.2 2.6 2.2 1 1 1 2 2 2 2 MFS/sugar transport protein MFS_4 PF06779.14 KFX90759.1 - 0.0019 17.6 5.7 0.0026 17.1 5.7 1.1 1 0 0 1 1 1 1 Uncharacterised MFS-type transporter YbfB TRI12 PF06609.13 KFX90759.1 - 0.03 12.8 4.3 0.041 12.3 4.3 1.1 1 0 0 1 1 1 0 Fungal trichothecene efflux pump (TRI12) OATP PF03137.20 KFX90759.1 - 0.067 11.5 3.1 0.16 10.2 0.1 2.1 1 1 1 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family WD40 PF00400.32 KFX90761.1 - 2.2e-13 50.4 12.1 0.0053 17.6 0.0 6.8 7 0 0 7 7 7 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFX90761.1 - 0.00015 21.9 0.0 0.21 11.9 0.0 3.9 5 1 0 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 KFX90761.1 - 0.0049 16.8 0.1 4.9 7.2 0.0 3.2 2 0 0 2 2 2 2 WD40-like Beta Propeller Repeat DUF1664 PF07889.12 KFX90762.1 - 0.0062 16.6 0.1 0.0079 16.2 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1664) APG6_N PF17675.1 KFX90762.1 - 0.013 16.0 4.8 0.016 15.7 4.8 1.2 1 0 0 1 1 1 0 Apg6 coiled-coil region CCDC-167 PF15188.6 KFX90762.1 - 0.11 12.9 0.8 0.16 12.4 0.8 1.2 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 167 DUF2922 PF11148.8 KFX90762.1 - 0.11 12.2 0.2 0.19 11.5 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2922) FUSC PF04632.12 KFX90762.1 - 0.11 11.0 1.8 0.12 10.9 1.8 1.0 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF2730 PF10805.8 KFX90762.1 - 0.15 12.1 0.1 0.21 11.7 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2730) Glyco_hydro_18 PF00704.28 KFX90769.1 - 1.6e-25 90.5 0.3 7.9e-25 88.2 0.3 1.8 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 Glyco_hydro_18 PF00704.28 KFX90770.1 - 5.1e-88 295.8 6.1 6e-88 295.6 6.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 LRR_6 PF13516.6 KFX90773.1 - 0.05 13.7 16.6 25 5.3 0.1 7.5 8 0 0 8 8 8 0 Leucine Rich repeat MFS_1 PF07690.16 KFX90774.1 - 8.4e-31 107.2 37.9 8.4e-31 107.2 37.9 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily UNC-93 PF05978.16 KFX90774.1 - 0.012 15.4 3.9 0.023 14.4 3.9 1.6 1 0 0 1 1 1 0 Ion channel regulatory protein UNC-93 K_oxygenase PF13434.6 KFX90775.1 - 1.6e-14 53.9 0.0 1.3e-09 37.6 0.0 2.3 2 0 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.6 KFX90775.1 - 2.4e-13 50.0 0.0 3.8e-12 46.1 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 KFX90775.1 - 3.6e-10 38.9 0.0 1.5e-09 36.8 0.0 1.8 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 KFX90775.1 - 8e-08 31.9 0.0 6.9e-05 22.2 0.0 2.8 2 1 1 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.20 KFX90775.1 - 0.002 18.2 0.0 0.0045 17.0 0.0 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase SnoaL_4 PF13577.6 KFX90775.1 - 0.0034 17.5 0.7 0.019 15.1 0.7 2.3 1 1 0 1 1 1 1 SnoaL-like domain SnoaL_2 PF12680.7 KFX90775.1 - 0.0059 17.2 0.1 0.036 14.7 0.0 2.2 2 0 0 2 2 2 1 SnoaL-like domain Pyr_redox PF00070.27 KFX90775.1 - 0.011 16.3 2.5 0.065 13.8 0.3 2.9 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase DUF4440 PF14534.6 KFX90775.1 - 0.014 15.8 0.1 0.043 14.2 0.1 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4440) AMP-binding PF00501.28 KFX90776.1 - 8.5e-94 314.5 0.0 1.1e-93 314.2 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KFX90776.1 - 6.4e-13 49.5 0.2 1.3e-12 48.5 0.2 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain SUI1 PF01253.22 KFX90781.1 - 2e-25 89.1 0.2 4.6e-25 88.0 0.2 1.6 1 0 0 1 1 1 1 Translation initiation factor SUI1 BNR_6 PF15899.5 KFX90781.1 - 0.1 12.7 0.2 0.22 11.6 0.2 1.6 1 0 0 1 1 1 0 BNR-Asp box repeat Img2 PF05046.14 KFX90781.1 - 0.11 12.7 0.0 0.24 11.7 0.0 1.6 1 0 0 1 1 1 0 Mitochondrial large subunit ribosomal protein (Img2) CcmH PF03918.14 KFX90781.1 - 0.21 10.9 1.3 0.4 10.0 0.0 1.9 2 0 0 2 2 2 0 Cytochrome C biogenesis protein Nbl1_Borealin_N PF10444.9 KFX90782.1 - 2e-19 69.0 1.4 3.3e-19 68.3 1.4 1.4 1 0 0 1 1 1 1 Nbl1 / Borealin N terminal VWA_2 PF13519.6 KFX90783.1 - 3.2e-27 95.3 0.3 7.5e-27 94.1 0.0 1.7 2 0 0 2 2 2 1 von Willebrand factor type A domain VWA PF00092.28 KFX90783.1 - 7.3e-11 42.6 0.4 1e-10 42.2 0.4 1.1 1 0 0 1 1 1 1 von Willebrand factor type A domain Ssl1 PF04056.14 KFX90783.1 - 5.4e-07 29.6 0.1 8.1e-07 29.0 0.1 1.2 1 0 0 1 1 1 1 Ssl1-like UIM PF02809.20 KFX90783.1 - 0.009 15.9 1.1 0.022 14.7 1.1 1.7 1 0 0 1 1 1 1 Ubiquitin interaction motif DUF871 PF05913.11 KFX90783.1 - 0.072 12.3 0.1 0.11 11.7 0.1 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF871) Sybindin PF04099.12 KFX90784.1 - 4.2e-51 172.6 0.0 5.4e-51 172.3 0.0 1.1 1 0 0 1 1 1 1 Sybindin-like family Sedlin_N PF04628.13 KFX90784.1 - 1.1e-09 38.5 0.0 1.8e-09 37.8 0.0 1.3 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region Got1 PF04178.12 KFX90788.1 - 7.6e-35 119.7 15.7 1.2e-34 119.1 15.7 1.3 1 0 0 1 1 1 1 Got1/Sft2-like family NuA4 PF09340.10 KFX90791.1 - 8.6e-25 86.4 0.1 1.7e-24 85.5 0.1 1.5 1 0 0 1 1 1 1 Histone acetyltransferase subunit NuA4 RNase_PH PF01138.21 KFX90795.1 - 1.4e-33 116.2 0.0 2.8e-33 115.2 0.0 1.5 2 0 0 2 2 2 1 3' exoribonuclease family, domain 1 Thioredoxin PF00085.20 KFX90796.1 - 4.3e-33 113.4 0.1 1e-26 92.9 0.1 2.6 2 0 0 2 2 2 2 Thioredoxin Thioredoxin_2 PF13098.6 KFX90796.1 - 8.3e-07 29.4 0.8 0.022 15.2 0.1 3.1 2 1 1 3 3 3 2 Thioredoxin-like domain OST3_OST6 PF04756.13 KFX90796.1 - 1.1e-06 28.2 0.6 4.3e-06 26.3 0.0 2.2 2 1 0 2 2 2 1 OST3 / OST6 family, transporter family TraF PF13728.6 KFX90796.1 - 1.8e-05 24.7 9.7 0.0017 18.2 0.0 3.3 3 0 0 3 3 3 1 F plasmid transfer operon protein Thioredoxin_6 PF13848.6 KFX90796.1 - 1.9e-05 24.7 1.2 0.0022 17.9 0.0 2.6 3 0 0 3 3 2 1 Thioredoxin-like domain Thioredoxin_8 PF13905.6 KFX90796.1 - 0.0023 18.2 0.0 0.22 11.9 0.0 3.3 3 1 0 3 3 3 1 Thioredoxin-like AhpC-TSA PF00578.21 KFX90796.1 - 0.034 14.1 0.0 0.096 12.6 0.0 1.7 1 0 0 1 1 1 0 AhpC/TSA family Thioredoxin_7 PF13899.6 KFX90796.1 - 0.05 13.8 0.0 0.15 12.3 0.0 1.8 1 0 0 1 1 1 0 Thioredoxin-like Thioredoxin_3 PF13192.6 KFX90796.1 - 0.08 13.0 0.1 2.2 8.4 0.1 2.8 3 0 0 3 3 2 0 Thioredoxin domain U1snRNP70_N PF12220.8 KFX90796.1 - 0.1 13.3 5.6 0.067 13.8 2.7 2.3 1 1 1 2 2 2 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal TRAP_alpha PF03896.16 KFX90796.1 - 0.11 11.7 3.0 0.22 10.7 1.5 1.9 2 0 0 2 2 2 0 Translocon-associated protein (TRAP), alpha subunit X PF00739.19 KFX90796.1 - 0.14 12.3 0.1 0.53 10.4 0.0 2.0 2 0 0 2 2 2 0 Trans-activation protein X S_layer_C PF05124.12 KFX90796.1 - 0.61 10.0 5.6 0.27 11.2 2.8 1.8 2 0 0 2 2 2 0 S-layer like family, C-terminal region NARP1 PF12569.8 KFX90796.1 - 2.7 6.8 10.8 4.2 6.2 10.8 1.2 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Presenilin PF01080.17 KFX90796.1 - 4.2 6.0 5.9 6.4 5.4 5.9 1.2 1 0 0 1 1 1 0 Presenilin RNA_pol_Rpc4 PF05132.14 KFX90796.1 - 5 7.5 8.5 11 6.4 8.5 1.6 1 0 0 1 1 1 0 RNA polymerase III RPC4 Ank_3 PF13606.6 KFX90798.1 - 0.14 12.8 0.1 1.3e+02 3.7 0.0 3.9 4 1 1 5 5 5 0 Ankyrin repeat TIM PF00121.18 KFX90803.1 - 1.3e-89 299.7 0.4 1.5e-89 299.6 0.4 1.0 1 0 0 1 1 1 1 Triosephosphate isomerase FtsZ_C PF12327.8 KFX90803.1 - 0.045 14.0 0.6 15 5.9 0.1 3.1 2 1 0 2 2 2 0 FtsZ family, C-terminal domain L51_S25_CI-B8 PF05047.16 KFX90804.1 - 7.8e-15 54.5 0.0 1.1e-14 54.0 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain U1snRNP70_N PF12220.8 KFX90805.1 - 2.9e-26 91.9 3.6 2.9e-26 91.9 3.6 2.1 3 0 0 3 3 3 1 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal RRM_1 PF00076.22 KFX90805.1 - 3.9e-17 61.8 0.3 1.4e-16 60.0 0.3 1.9 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KFX90805.1 - 5.8e-06 26.3 0.0 9.8e-06 25.6 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif STAG PF08514.11 KFX90806.1 - 1.3e-31 108.8 0.3 5.9e-31 106.7 0.3 2.2 1 0 0 1 1 1 1 STAG domain Histidinol_dh PF00815.20 KFX90806.1 - 7.6e-06 25.2 0.2 1.6e-05 24.1 0.2 1.5 1 0 0 1 1 1 1 Histidinol dehydrogenase HEAT_2 PF13646.6 KFX90806.1 - 2e-05 24.9 0.0 0.0099 16.2 0.0 3.0 1 1 1 2 2 2 2 HEAT repeats HEAT PF02985.22 KFX90806.1 - 0.0058 16.8 1.3 24 5.6 0.0 4.7 6 0 0 6 6 6 2 HEAT repeat HATPase_c_3 PF13589.6 KFX90808.1 - 7.3e-17 61.5 0.0 1.4e-16 60.5 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 KFX90808.1 - 0.00096 19.6 0.0 0.0022 18.5 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase MutL_C PF08676.11 KFX90808.1 - 0.02 14.7 0.0 0.04 13.7 0.0 1.5 1 0 0 1 1 1 0 MutL C terminal dimerisation domain CFEM PF05730.11 KFX90809.1 - 0.14 12.2 10.1 0.24 11.5 10.1 1.3 1 0 0 1 1 1 0 CFEM domain Dabb PF07876.12 KFX90810.1 - 9.7e-21 74.2 0.1 1.1e-20 74.0 0.1 1.0 1 0 0 1 1 1 1 Stress responsive A/B Barrel Domain GHMP_kinases_N PF00288.26 KFX90811.1 - 3.3e-10 40.1 0.2 8.2e-10 38.8 0.2 1.7 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 KFX90811.1 - 4.9e-05 23.6 0.0 9.6e-05 22.7 0.0 1.5 1 0 0 1 1 1 1 GHMP kinases C terminal NPP1 PF05630.11 KFX90819.1 - 4.1e-06 27.1 7.2 2.4e-05 24.5 7.2 2.1 1 1 0 1 1 1 1 Necrosis inducing protein (NPP1) Glyco_hydro_28 PF00295.17 KFX90820.1 - 1.9e-53 181.7 1.8 2.5e-53 181.3 1.8 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 ET PF01684.16 KFX90820.1 - 0.059 13.7 0.1 0.13 12.6 0.1 1.5 1 0 0 1 1 1 0 ET module ORC6 PF05460.13 KFX90822.1 - 2.5e-38 132.3 6.9 7.8e-32 110.9 0.9 2.1 2 0 0 2 2 2 2 Origin recognition complex subunit 6 (ORC6) EF-hand_6 PF13405.6 KFX90823.1 - 3.8e-07 29.5 2.3 0.029 14.3 0.0 2.7 3 0 0 3 3 3 2 EF-hand domain EF-hand_7 PF13499.6 KFX90823.1 - 2.9e-06 27.7 2.2 0.005 17.3 0.0 2.2 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 KFX90823.1 - 1.5e-05 24.3 0.7 3.1e-05 23.3 0.0 1.9 2 0 0 2 2 2 1 EF hand EF-hand_1 PF00036.32 KFX90823.1 - 2.6e-05 23.5 0.7 0.00015 21.0 0.0 2.2 2 0 0 2 2 2 1 EF hand EF-hand_8 PF13833.6 KFX90823.1 - 0.033 14.0 0.7 0.069 13.0 0.3 1.8 1 1 1 2 2 2 0 EF-hand domain pair cobW PF02492.19 KFX90825.1 - 3.5e-20 72.3 0.0 4.6e-20 71.9 0.0 1.1 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain MeaB PF03308.16 KFX90825.1 - 0.0042 16.1 0.1 0.0048 15.9 0.1 1.1 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB PA26 PF04636.13 KFX90826.1 - 0.11 11.4 1.2 0.19 10.6 1.2 1.3 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) DUF4554 PF15091.6 KFX90826.1 - 0.44 9.4 5.3 1.1 8.1 5.3 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4554) Peptidase_S49_N PF08496.10 KFX90826.1 - 3.3 7.8 14.0 6.9 6.7 14.0 1.4 1 0 0 1 1 1 0 Peptidase family S49 N-terminal SKN1 PF03935.15 KFX90827.1 - 3.2e-226 751.6 0.4 3.7e-226 751.3 0.4 1.0 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) CHD5 PF04420.14 KFX90829.1 - 3.3e-59 199.3 1.0 4.4e-59 198.9 1.0 1.2 1 0 0 1 1 1 1 CHD5-like protein PPTA PF01239.22 KFX90830.1 - 5.5e-06 25.9 16.9 0.0015 18.2 0.8 4.2 5 0 0 5 5 5 3 Protein prenyltransferase alpha subunit repeat Asp PF00026.23 KFX90832.1 - 2.4e-67 227.6 3.3 3e-67 227.3 3.3 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KFX90832.1 - 2.2e-08 34.6 5.0 2.4e-07 31.2 0.3 3.1 2 2 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 KFX90832.1 - 6.1e-05 23.6 0.1 0.81 10.4 0.0 3.1 2 1 0 2 2 2 2 Aspartyl protease gag-asp_proteas PF13975.6 KFX90832.1 - 0.00085 19.8 0.1 0.72 10.5 0.0 2.9 2 0 0 2 2 2 2 gag-polyprotein putative aspartyl protease TAXi_C PF14541.6 KFX90832.1 - 0.0095 15.7 0.0 0.16 11.7 0.0 2.2 1 1 1 2 2 2 1 Xylanase inhibitor C-terminal DNA_methylase PF00145.17 KFX90833.1 - 0.097 12.0 2.2 0.11 11.8 2.2 1.1 1 0 0 1 1 1 0 C-5 cytosine-specific DNA methylase SR-25 PF10500.9 KFX90848.1 - 0.0021 17.7 3.9 0.0024 17.5 3.9 1.1 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein Med19 PF10278.9 KFX90848.1 - 0.021 14.7 9.6 0.025 14.5 9.6 1.1 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 RNA_pol_Rpc4 PF05132.14 KFX90848.1 - 0.095 13.1 5.4 0.11 12.9 5.4 1.1 1 0 0 1 1 1 0 RNA polymerase III RPC4 VAD1-2 PF15310.6 KFX90848.1 - 0.18 11.6 6.5 0.23 11.3 6.5 1.1 1 0 0 1 1 1 0 Vitamin A-deficiency (VAD) rat model signalling JmjC PF02373.22 KFX90849.1 - 4.7e-40 136.6 0.3 1.2e-39 135.3 0.3 1.7 1 0 0 1 1 1 1 JmjC domain, hydroxylase zf-HC5HC2H_2 PF13832.6 KFX90849.1 - 1.9e-18 66.6 3.6 3.4e-18 65.8 3.6 1.4 1 0 0 1 1 1 1 PHD-zinc-finger like domain zf-HC5HC2H PF13771.6 KFX90849.1 - 3.7e-15 56.0 2.1 9.2e-15 54.7 2.1 1.7 1 0 0 1 1 1 1 PHD-like zinc-binding domain CEBP_ZZ PF16366.5 KFX90849.1 - 0.48 10.7 3.9 1.5 9.1 3.9 1.8 1 0 0 1 1 1 0 Cytoplasmic polyadenylation element-binding protein ZZ domain Mcl1_mid PF12341.8 KFX90864.1 - 8.5e-96 320.8 0.1 3.8e-95 318.7 0.0 2.1 2 1 0 2 2 2 1 Minichromosome loss protein, Mcl1, middle region WD40 PF00400.32 KFX90864.1 - 1.1e-21 76.7 4.8 4.8e-08 33.5 0.1 7.4 8 0 0 8 8 8 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFX90864.1 - 3.7e-18 65.6 0.0 6.8e-05 23.1 0.0 7.0 3 2 4 7 7 7 4 Anaphase-promoting complex subunit 4 WD40 domain Coatomer_WDAD PF04053.14 KFX90864.1 - 3.2e-07 29.8 0.0 7.8e-07 28.5 0.0 1.6 2 0 0 2 2 2 1 Coatomer WD associated region eIF2A PF08662.11 KFX90864.1 - 0.00034 20.6 0.1 0.034 14.0 0.0 3.1 2 1 1 3 3 3 1 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 KFX90864.1 - 0.027 13.4 0.0 6.4 5.6 0.0 3.2 2 1 2 4 4 4 0 WD40 region of Ge1, enhancer of mRNA-decapping protein IKI3 PF04762.12 KFX90864.1 - 0.034 12.1 0.1 0.11 10.5 0.1 1.8 1 1 0 1 1 1 0 IKI3 family DNA_pol_alpha_N PF12254.8 KFX90864.1 - 0.1 12.7 3.4 0.27 11.3 3.4 1.7 1 0 0 1 1 1 0 DNA polymerase alpha subunit p180 N terminal WD40 PF00400.32 KFX90865.1 - 7.9e-14 51.8 14.0 0.00075 20.3 0.0 5.9 6 0 0 6 6 6 5 WD domain, G-beta repeat PQQ_3 PF13570.6 KFX90865.1 - 0.99 10.0 3.8 3.1 8.4 0.0 3.6 4 0 0 4 4 4 0 PQQ-like domain NOA36 PF06524.12 KFX90866.1 - 2.4 7.4 4.9 0.66 9.2 1.3 1.7 2 0 0 2 2 2 0 NOA36 protein Ku PF02735.16 KFX90867.1 - 6.1e-37 127.3 0.0 1.1e-36 126.5 0.0 1.4 1 0 0 1 1 1 1 Ku70/Ku80 beta-barrel domain Ku_N PF03731.15 KFX90867.1 - 5e-34 118.0 0.0 6.8e-34 117.5 0.0 1.2 1 0 0 1 1 1 1 Ku70/Ku80 N-terminal alpha/beta domain Complex1_51K PF01512.17 KFX90867.1 - 0.18 11.6 0.0 0.43 10.4 0.0 1.6 1 0 0 1 1 1 0 Respiratory-chain NADH dehydrogenase 51 Kd subunit Ferrochelatase PF00762.19 KFX90868.1 - 1.1e-96 323.7 0.0 1.3e-96 323.4 0.0 1.0 1 0 0 1 1 1 1 Ferrochelatase MFS_1 PF07690.16 KFX90869.1 - 7.4e-23 81.0 38.4 1.1e-16 60.7 24.2 2.5 2 1 1 3 3 3 2 Major Facilitator Superfamily Amidohydro_1 PF01979.20 KFX90870.1 - 2.2e-64 218.0 0.0 3e-64 217.5 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 KFX90870.1 - 1.3e-09 38.1 0.0 2e-09 37.4 0.0 1.2 1 0 0 1 1 1 1 Amidohydrolase family cNMP_binding PF00027.29 KFX90871.1 - 1.1e-30 105.5 0.2 5.1e-18 64.9 0.0 5.5 6 0 0 6 6 6 3 Cyclic nucleotide-binding domain Patatin PF01734.22 KFX90871.1 - 1.3e-16 61.4 8.1 9.6e-16 58.6 6.1 3.1 2 1 0 2 2 2 1 Patatin-like phospholipase EIF_2_alpha PF07541.12 KFX90872.1 - 2.9e-36 124.1 0.0 5.2e-36 123.3 0.0 1.4 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 2 alpha subunit S1 PF00575.23 KFX90872.1 - 5.1e-13 49.2 1.0 1.1e-12 48.1 1.0 1.5 1 0 0 1 1 1 1 S1 RNA binding domain Peptidase_S24 PF00717.23 KFX90872.1 - 0.00035 20.4 0.3 0.0045 16.9 0.0 2.8 2 1 0 2 2 2 1 Peptidase S24-like Peptidase_S26 PF10502.9 KFX90872.1 - 0.0028 17.5 0.0 0.03 14.1 0.0 2.3 1 1 1 2 2 2 1 Signal peptidase, peptidase S26 Bacteriocin_IIi PF11758.8 KFX90872.1 - 0.17 11.7 0.1 0.17 11.7 0.1 2.2 2 0 0 2 2 2 0 Aureocin-like type II bacteriocin Mito_carr PF00153.27 KFX90873.1 - 1.6e-63 210.6 5.3 1.7e-20 72.7 0.9 3.4 3 1 0 3 3 3 3 Mitochondrial carrier protein Ribonuc_L-PSP PF01042.21 KFX90874.1 - 6.3e-25 87.5 0.0 7.4e-25 87.3 0.0 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP KAR9 PF08580.10 KFX90897.1 - 4.4e-161 537.8 7.6 1.1e-160 536.5 6.6 1.9 1 1 0 1 1 1 1 Yeast cortical protein KAR9 Apolipoprotein PF01442.18 KFX90897.1 - 0.0077 16.1 3.1 0.025 14.5 3.1 1.8 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain Fib_alpha PF08702.10 KFX90897.1 - 0.071 13.3 1.5 7.3 6.8 0.0 2.4 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family Spectrin PF00435.21 KFX90897.1 - 1 9.9 12.6 7.6 7.1 0.0 4.7 4 1 0 4 4 4 0 Spectrin repeat THOC7 PF05615.13 KFX90897.1 - 3.6 7.9 5.8 20 5.5 3.0 3.1 2 1 0 2 2 2 0 Tho complex subunit 7 Syntaxin-6_N PF09177.11 KFX90897.1 - 5.4 7.6 11.2 1.4 9.5 0.8 3.8 2 2 0 3 3 3 0 Syntaxin 6, N-terminal Amidase PF01425.21 KFX90901.1 - 1.6e-78 264.7 0.1 1.3e-76 258.4 0.0 2.0 2 0 0 2 2 2 2 Amidase Histone PF00125.24 KFX90902.1 - 3.7e-18 66.1 0.0 4.9e-18 65.8 0.0 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Histone_H2A_C PF16211.5 KFX90902.1 - 1.1e-12 47.5 0.1 2.5e-12 46.3 0.1 1.6 1 0 0 1 1 1 1 C-terminus of histone H2A CBFD_NFYB_HMF PF00808.23 KFX90902.1 - 3.4e-05 24.0 0.0 5e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Peptidase_M64 PF09471.10 KFX90902.1 - 0.087 12.4 0.0 0.12 11.9 0.0 1.1 1 0 0 1 1 1 0 IgA Peptidase M64 zf-H2C2_2 PF13465.6 KFX90913.1 - 2.5e-12 46.6 9.4 2.9e-07 30.6 0.4 3.9 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2 PF00096.26 KFX90913.1 - 4.4e-12 45.7 12.8 3.9e-06 27.0 2.4 3.9 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFX90913.1 - 2.7e-08 34.0 11.3 0.00044 20.8 1.5 4.1 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_6 PF13912.6 KFX90913.1 - 6.3e-08 32.4 6.5 0.00035 20.5 0.3 3.8 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFX90913.1 - 1.7e-06 28.1 2.0 0.096 13.0 0.1 4.1 4 0 0 4 4 4 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KFX90913.1 - 4.5e-05 23.7 1.7 0.014 15.7 0.2 3.4 3 0 0 3 3 3 1 Zinc-finger of C2H2 type zf-Di19 PF05605.12 KFX90913.1 - 0.044 14.1 1.9 0.095 13.0 1.9 1.5 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_11 PF16622.5 KFX90913.1 - 0.72 9.7 8.3 0.45 10.3 0.7 2.8 3 0 0 3 3 3 0 zinc-finger C2H2-type C5HCH PF17982.1 KFX90913.1 - 6.7 6.9 6.7 28 5.0 0.4 2.5 1 1 1 2 2 2 0 NSD Cys-His rich domain LIM PF00412.22 KFX90913.1 - 7.2 6.9 8.2 20 5.5 0.1 3.1 2 1 1 3 3 3 0 LIM domain DUF411 PF04214.13 KFX90914.1 - 0.039 13.9 0.1 0.072 13.0 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF Apt1 PF10351.9 KFX90915.1 - 2.3 6.9 10.1 3.5 6.4 10.1 1.4 1 0 0 1 1 1 0 Golgi-body localisation protein domain Pkinase PF00069.25 KFX90916.1 - 1e-48 166.0 0.0 8.6e-28 97.4 0.0 2.8 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KFX90916.1 - 5.2e-22 78.4 0.0 1.2e-14 54.2 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase APH PF01636.23 KFX90916.1 - 0.0016 18.4 1.4 0.0029 17.6 0.3 2.0 2 1 0 2 2 2 1 Phosphotransferase enzyme family Tricorn_PDZ PF14685.6 KFX90916.1 - 0.037 14.0 0.0 0.096 12.7 0.0 1.6 1 0 0 1 1 1 0 Tricorn protease PDZ domain Haspin_kinase PF12330.8 KFX90916.1 - 0.058 12.3 0.0 0.088 11.7 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Pox_ser-thr_kin PF05445.11 KFX90916.1 - 0.091 11.7 0.0 0.15 11.0 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase PS_Dcarbxylase PF02666.15 KFX90917.1 - 3.3e-19 69.2 0.0 5.5e-19 68.5 0.0 1.4 1 1 0 1 1 1 1 Phosphatidylserine decarboxylase DUF2407 PF10302.9 KFX90918.1 - 1e-06 29.2 0.1 3e-06 27.7 0.1 1.8 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain ubiquitin PF00240.23 KFX90918.1 - 1.2e-05 24.9 0.0 2.4e-05 24.0 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 KFX90918.1 - 0.022 14.6 0.0 0.041 13.7 0.0 1.3 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like Blt1 PF12754.7 KFX90918.1 - 0.071 13.4 3.0 1.3 9.3 0.0 2.6 2 0 0 2 2 2 0 Blt1 N-terminal domain Rad60-SLD_2 PF13881.6 KFX90918.1 - 0.075 13.1 0.0 0.28 11.3 0.0 1.9 2 0 0 2 2 2 0 Ubiquitin-2 like Rad60 SUMO-like DUF1729 PF08354.10 KFX90918.1 - 0.11 11.4 0.1 0.21 10.5 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1729) DUF1996 PF09362.10 KFX90936.1 - 2.7e-84 282.8 0.2 3.4e-84 282.5 0.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) P16-Arc PF04699.14 KFX90938.1 - 8.6e-32 110.7 0.0 1.1e-31 110.3 0.0 1.2 1 0 0 1 1 1 1 ARP2/3 complex 16 kDa subunit (p16-Arc) Polysacc_lyase PF14099.6 KFX90945.1 - 3.8e-11 43.2 1.5 7.1e-11 42.3 1.5 1.4 1 1 0 1 1 1 1 Polysaccharide lyase PP2C PF00481.21 KFX90946.1 - 2.3e-53 181.5 0.0 4e-53 180.7 0.0 1.4 1 0 0 1 1 1 1 Protein phosphatase 2C LRR_8 PF13855.6 KFX90946.1 - 2.2e-42 142.6 47.9 2e-08 33.8 0.7 9.7 5 3 4 10 10 10 9 Leucine rich repeat Guanylate_cyc PF00211.20 KFX90946.1 - 2.9e-28 98.8 0.0 1.7e-27 96.2 0.0 2.0 2 0 0 2 2 2 1 Adenylate and Guanylate cyclase catalytic domain LRR_4 PF12799.7 KFX90946.1 - 4.5e-28 96.8 61.2 0.0014 19.0 0.2 11.8 7 3 5 14 14 14 11 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 KFX90946.1 - 1.6e-07 30.9 47.0 4.2 8.3 0.0 15.4 17 0 0 17 17 17 3 Leucine Rich Repeat LRR_9 PF14580.6 KFX90946.1 - 4.2e-06 26.4 19.8 0.00019 21.0 0.2 5.4 4 1 1 6 6 6 2 Leucine-rich repeat Ad_cyc_g-alpha PF08509.11 KFX90946.1 - 4.5e-06 26.3 1.8 6.4e-06 25.8 0.0 2.2 2 0 0 2 2 2 1 Adenylate cyclase G-alpha binding domain RA PF00788.23 KFX90946.1 - 6.2e-06 26.7 0.0 1.4e-05 25.6 0.0 1.6 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain LRR_5 PF13306.6 KFX90946.1 - 0.012 15.6 0.0 12 5.8 0.1 3.4 3 0 0 3 3 3 0 BspA type Leucine rich repeat region (6 copies) DAHP_synth_2 PF01474.16 KFX90954.1 - 6.2e-200 664.3 0.0 7.1e-200 664.1 0.0 1.0 1 0 0 1 1 1 1 Class-II DAHP synthetase family Condensation PF00668.20 KFX90956.1 - 4.1e-42 144.4 0.0 1.3e-30 106.5 0.0 2.6 2 1 0 2 2 2 2 Condensation domain PP-binding PF00550.25 KFX90956.1 - 2.3e-08 34.3 0.0 5.6e-08 33.0 0.0 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site Tctex-1 PF03645.13 KFX90957.1 - 2.8e-09 37.1 0.1 3.2e-09 36.9 0.1 1.1 1 0 0 1 1 1 1 Tctex-1 family UQ_con PF00179.26 KFX90961.1 - 1.2e-25 89.8 0.0 1.6e-25 89.4 0.0 1.3 1 1 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 KFX90961.1 - 0.02 15.2 0.1 0.044 14.1 0.1 1.6 1 1 0 1 1 1 0 RWD domain UFC1 PF08694.11 KFX90961.1 - 0.027 14.1 0.0 0.034 13.8 0.0 1.3 1 1 0 1 1 1 0 Ubiquitin-fold modifier-conjugating enzyme 1 Prok-E2_B PF14461.6 KFX90961.1 - 0.029 14.1 0.0 0.041 13.6 0.0 1.2 1 0 0 1 1 1 0 Prokaryotic E2 family B UEV PF05743.13 KFX90961.1 - 0.031 14.1 0.0 0.053 13.4 0.0 1.3 1 0 0 1 1 1 0 UEV domain DUF4246 PF14033.6 KFX90980.1 - 2.7e-84 283.9 0.0 3.3e-84 283.6 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4246) 2OG-FeII_Oxy_5 PF13759.6 KFX90980.1 - 0.011 16.1 0.0 0.026 14.9 0.0 1.7 1 0 0 1 1 1 0 Putative 2OG-Fe(II) oxygenase 2OG-FeII_Oxy_3 PF13640.6 KFX90980.1 - 0.013 16.3 0.0 0.039 14.8 0.0 1.8 1 1 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily Aminotran_3 PF00202.21 KFX90981.1 - 4.9e-65 219.8 0.0 5.4e-65 219.6 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III HA2 PF04408.23 KFX90982.1 - 2.2e-24 85.8 1.9 6.9e-24 84.2 0.0 2.6 2 0 0 2 2 2 1 Helicase associated domain (HA2) Helicase_C PF00271.31 KFX90982.1 - 5.1e-12 46.1 0.2 1.2e-10 41.7 0.0 3.0 3 1 0 3 3 3 1 Helicase conserved C-terminal domain OB_NTP_bind PF07717.16 KFX90982.1 - 1.7e-11 44.3 0.0 4.4e-11 43.0 0.0 1.8 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold DEAD PF00270.29 KFX90982.1 - 6.5e-07 29.3 0.0 7.1e-06 25.9 0.0 2.3 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_22 PF13401.6 KFX90982.1 - 0.0042 17.4 0.0 0.018 15.4 0.0 2.1 1 0 0 1 1 1 1 AAA domain T2SSE PF00437.20 KFX90982.1 - 0.013 14.5 0.1 0.034 13.2 0.0 1.6 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_19 PF13245.6 KFX90982.1 - 0.046 14.0 0.0 0.11 12.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.18 KFX90982.1 - 0.06 12.7 0.0 0.15 11.4 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family ATPase PF06745.13 KFX90982.1 - 0.071 12.5 0.0 0.15 11.3 0.0 1.5 1 0 0 1 1 1 0 KaiC DIOX_N PF14226.6 KFX90984.1 - 4.1e-22 79.1 0.0 7.8e-22 78.2 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 KFX90984.1 - 7.9e-21 74.4 0.0 4e-20 72.2 0.0 2.1 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily Transcrip_reg PF01709.20 KFX90985.1 - 6.3e-67 225.5 0.0 7.2e-67 225.3 0.0 1.0 1 0 0 1 1 1 1 Transcriptional regulator tRNA-synt_1b PF00579.25 KFX90986.1 - 1.4e-55 188.7 0.0 2e-55 188.2 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) HSP20 PF00011.21 KFX90987.1 - 8.3e-10 38.7 0.1 1.1e-09 38.3 0.1 1.2 1 0 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 KFX90987.1 - 1.2e-05 24.8 0.1 0.0001 21.8 0.1 2.3 1 1 0 1 1 1 1 HSP20-like domain found in ArsA Ribosomal_60s PF00428.19 KFX90987.1 - 0.015 15.8 2.0 0.032 14.8 2.0 1.5 1 0 0 1 1 1 0 60s Acidic ribosomal protein MSC PF09402.10 KFX90988.1 - 1.2e-104 350.5 0.0 1.3e-104 350.3 0.0 1.0 1 0 0 1 1 1 1 Man1-Src1p-C-terminal domain Rif1_N PF12231.8 KFX90999.1 - 1.1e-131 439.2 0.0 1.7e-131 438.7 0.0 1.3 1 0 0 1 1 1 1 Rap1-interacting factor 1 N terminal zf-CCHC_4 PF14392.6 KFX91021.1 - 0.021 14.5 1.7 0.044 13.5 1.7 1.5 1 0 0 1 1 1 0 Zinc knuckle VWD PF00094.25 KFX91021.1 - 0.035 14.4 0.1 0.036 14.3 0.1 1.2 1 0 0 1 1 1 0 von Willebrand factor type D domain DUF3128 PF11326.8 KFX91023.1 - 4.6 7.7 8.2 0.23 11.8 2.7 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3128) GRAB PF10375.9 KFX91024.1 - 8.8e-07 28.6 0.1 1.7e-06 27.6 0.1 1.5 1 0 0 1 1 1 1 GRIP-related Arf-binding domain BLOC1_2 PF10046.9 KFX91024.1 - 0.00068 19.9 9.0 0.00068 19.9 9.0 4.1 2 2 3 5 5 5 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 RPW8 PF05659.11 KFX91024.1 - 0.0045 16.7 0.7 0.0045 16.7 0.7 2.9 2 1 1 3 3 3 1 Arabidopsis broad-spectrum mildew resistance protein RPW8 EzrA PF06160.12 KFX91024.1 - 0.13 10.4 35.7 0.44 8.7 21.5 2.8 1 1 1 2 2 2 0 Septation ring formation regulator, EzrA DUF3584 PF12128.8 KFX91024.1 - 0.17 9.4 44.9 0.3 8.5 44.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Golgin_A5 PF09787.9 KFX91024.1 - 1.2 8.5 50.3 1.2 8.5 21.4 3.1 1 1 2 3 3 3 0 Golgin subfamily A member 5 CENP-F_leu_zip PF10473.9 KFX91024.1 - 1.4 8.9 55.9 0.18 11.9 16.4 3.5 1 1 2 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Spc7 PF08317.11 KFX91024.1 - 1.5 7.7 51.6 2.8 6.8 30.8 3.0 1 1 1 2 2 2 0 Spc7 kinetochore protein HOOK PF05622.12 KFX91024.1 - 1.5 6.9 48.4 1.7 6.7 38.0 2.1 1 1 1 2 2 2 0 HOOK protein FPP PF05911.11 KFX91024.1 - 1.6 6.8 42.5 0.19 9.9 19.3 2.2 1 1 1 2 2 2 0 Filament-like plant protein, long coiled-coil DUF1664 PF07889.12 KFX91024.1 - 1.9 8.5 20.8 2.7 8.0 2.7 3.5 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) Jnk-SapK_ap_N PF09744.9 KFX91024.1 - 2.1 8.6 56.1 42 4.3 29.9 4.3 1 1 2 3 3 3 0 JNK_SAPK-associated protein-1 NPV_P10 PF05531.12 KFX91024.1 - 5.6 7.5 21.9 10 6.7 0.3 4.9 2 2 2 4 4 4 0 Nucleopolyhedrovirus P10 protein COG2 PF06148.11 KFX91024.1 - 9.3 6.3 30.3 0.064 13.3 3.2 3.7 2 2 1 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 Filament PF00038.21 KFX91024.1 - 9.8 5.7 50.6 0.22 11.1 7.0 3.1 1 1 2 3 3 3 0 Intermediate filament protein Neugrin PF06413.11 KFX91025.1 - 1.7e-10 41.3 0.8 1.7e-10 41.3 0.8 2.1 2 0 0 2 2 2 1 Neugrin MRP-L20 PF12824.7 KFX91025.1 - 0.00098 19.3 6.5 0.00098 19.3 6.5 2.6 2 1 1 3 3 3 1 Mitochondrial ribosomal protein subunit L20 Aminotran_1_2 PF00155.21 KFX91026.1 - 6.7e-65 219.6 0.0 8e-65 219.4 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II DUF5471 PF17565.2 KFX91026.1 - 0.0033 17.7 0.4 0.0072 16.6 0.4 1.5 1 0 0 1 1 1 1 Family of unknown function (DUF5471) DegT_DnrJ_EryC1 PF01041.17 KFX91026.1 - 0.02 14.2 0.0 0.037 13.3 0.0 1.4 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family Cys_Met_Meta_PP PF01053.20 KFX91026.1 - 0.031 12.8 0.1 0.071 11.6 0.1 1.5 1 1 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme Beta_elim_lyase PF01212.21 KFX91026.1 - 0.072 12.4 0.0 0.12 11.6 0.0 1.3 1 0 0 1 1 1 0 Beta-eliminating lyase Methyltransf_11 PF08241.12 KFX91031.1 - 1.3e-18 67.5 0.0 1.9e-18 66.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KFX91031.1 - 7.4e-15 55.4 0.0 1.2e-14 54.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KFX91031.1 - 5.5e-11 43.1 0.0 8.6e-11 42.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KFX91031.1 - 1.2e-08 34.9 0.0 1.7e-08 34.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KFX91031.1 - 1.9e-06 27.8 0.0 2.8e-06 27.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain DREV PF05219.12 KFX91031.1 - 0.00016 20.8 0.0 0.00026 20.2 0.0 1.3 1 0 0 1 1 1 1 DREV methyltransferase Ubie_methyltran PF01209.18 KFX91031.1 - 0.0017 17.7 0.0 0.0026 17.1 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family tRNA_U5-meth_tr PF05958.11 KFX91031.1 - 0.027 13.5 0.0 0.039 13.0 0.0 1.1 1 0 0 1 1 1 0 tRNA (Uracil-5-)-methyltransferase NodS PF05401.11 KFX91031.1 - 0.05 13.2 0.0 0.075 12.6 0.0 1.2 1 0 0 1 1 1 0 Nodulation protein S (NodS) Methyltransf_18 PF12847.7 KFX91031.1 - 0.077 12.9 0.0 0.12 12.3 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain RrnaAD PF00398.20 KFX91031.1 - 0.17 10.9 0.0 0.23 10.5 0.0 1.1 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Glyco_hydro_26 PF02156.15 KFX91032.1 - 4.3e-76 256.3 1.6 5.8e-76 255.9 1.6 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 26 CBM_35 PF16990.5 KFX91032.1 - 1.2e-48 164.4 11.8 3e-25 88.8 2.0 2.4 2 0 0 2 2 2 2 Carbohydrate binding module (family 35) bMG6 PF17962.1 KFX91032.1 - 0.00081 19.5 0.2 6.3 7.0 0.0 3.6 3 0 0 3 3 3 2 Bacterial macroglobulin domain 6 DUF5010_C PF18099.1 KFX91032.1 - 0.0023 18.1 0.8 0.0063 16.6 0.2 1.9 2 0 0 2 2 2 1 DUF5010 C-terminal domain VirC2 PF07181.11 KFX91032.1 - 0.051 13.1 0.1 0.086 12.3 0.1 1.2 1 0 0 1 1 1 0 VirC2 protein Ice_nucleation PF00818.17 KFX91032.1 - 3.6 7.9 5.3 0.77 10.0 0.2 2.8 2 0 0 2 2 2 0 Ice nucleation protein repeat Yip1 PF04893.17 KFX91033.1 - 5.4e-13 49.0 14.3 5.4e-13 49.0 14.3 1.7 1 1 1 2 2 2 1 Yip1 domain YIF1 PF03878.15 KFX91033.1 - 0.037 13.5 3.6 0.09 12.3 2.6 2.0 2 1 0 2 2 2 0 YIF1 DDDD PF10161.9 KFX91033.1 - 0.097 12.4 0.0 0.59 9.9 0.0 2.3 2 0 0 2 2 2 0 Putative mitochondrial precursor protein His_Phos_1 PF00300.22 KFX91036.1 - 6.3e-34 117.4 0.0 8.2e-34 117.0 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Porin_3 PF01459.22 KFX91037.1 - 4.4e-71 239.5 6.0 5.5e-71 239.2 6.0 1.0 1 0 0 1 1 1 1 Eukaryotic porin OPT PF03169.15 KFX91046.1 - 5.7e-177 590.1 56.6 6.6e-177 589.9 56.6 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein DUF4191 PF13829.6 KFX91046.1 - 0.44 9.9 3.5 0.48 9.7 0.8 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4191) DUF2937 PF11157.8 KFX91046.1 - 0.48 10.1 2.8 4.2 7.1 0.1 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF2937) DUF2953 PF11167.8 KFX91046.1 - 1.2 9.2 4.8 0.36 10.9 0.3 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF2953) Gag_spuma PF03276.14 KFX91046.1 - 2.1 6.7 4.5 0.27 9.6 0.2 1.5 2 0 0 2 2 2 0 Spumavirus gag protein DASH_Spc34 PF08657.10 KFX91047.1 - 5.6e-26 91.9 1.6 6.6e-26 91.6 1.6 1.0 1 0 0 1 1 1 1 DASH complex subunit Spc34 MAP65_ASE1 PF03999.12 KFX91047.1 - 0.01 14.6 2.5 0.012 14.3 2.5 1.1 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) DUF724 PF05266.14 KFX91047.1 - 0.057 13.2 3.2 0.083 12.7 3.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF724) DASH_Spc19 PF08287.11 KFX91047.1 - 0.099 12.5 7.9 0.15 12.0 7.4 1.5 1 1 0 1 1 1 0 Spc19 KBP_C PF12309.8 KFX91047.1 - 0.11 12.0 4.4 0.15 11.6 4.4 1.1 1 0 0 1 1 1 0 KIF-1 binding protein C terminal DHR10 PF18595.1 KFX91047.1 - 0.45 10.6 10.8 1.7 8.8 2.6 2.3 2 0 0 2 2 2 0 Designed helical repeat protein 10 domain SlyX PF04102.12 KFX91047.1 - 0.63 10.7 9.4 1.7 9.3 2.3 2.3 1 1 1 2 2 2 0 SlyX Uds1 PF15456.6 KFX91047.1 - 1 9.5 7.0 1.8 8.7 6.8 1.5 1 1 0 1 1 1 0 Up-regulated During Septation HET PF06985.11 KFX91060.1 - 6.4e-26 91.5 0.1 1.7e-25 90.1 0.1 1.7 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) BRO1 PF03097.18 KFX91060.1 - 0.07 11.9 0.0 0.11 11.2 0.0 1.3 1 0 0 1 1 1 0 BRO1-like domain FAD_binding_3 PF01494.19 KFX91068.1 - 1.3e-55 189.1 0.0 1.6e-55 188.8 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 KFX91068.1 - 5e-06 25.5 0.1 0.011 14.4 0.0 2.2 2 0 0 2 2 2 2 HI0933-like protein DAO PF01266.24 KFX91068.1 - 0.00015 21.5 0.1 0.0038 16.8 0.0 2.2 1 1 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 KFX91068.1 - 0.002 17.5 0.0 0.024 13.9 0.1 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KFX91068.1 - 0.004 17.7 1.3 1.6 9.3 0.1 2.7 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KFX91068.1 - 0.0052 16.1 0.1 1.3 8.2 0.0 2.4 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KFX91068.1 - 0.032 13.3 0.1 1.8 7.5 0.0 2.3 2 0 0 2 2 2 0 FAD binding domain Thi4 PF01946.17 KFX91068.1 - 0.039 13.2 0.0 0.062 12.5 0.0 1.3 1 0 0 1 1 1 0 Thi4 family Lycopene_cycl PF05834.12 KFX91068.1 - 0.055 12.5 0.4 0.26 10.3 0.1 2.1 2 0 0 2 2 2 0 Lycopene cyclase protein NOB1_Zn_bind PF08772.11 KFX91078.1 - 7.2e-33 112.6 2.8 1.2e-32 111.9 2.8 1.4 1 0 0 1 1 1 1 Nin one binding (NOB1) Zn-ribbon like PIN_6 PF17146.4 KFX91078.1 - 6.6e-29 100.3 0.2 6.6e-29 100.3 0.2 2.4 2 1 0 2 2 2 1 PIN domain of ribonuclease zf-NADH-PPase PF09297.11 KFX91078.1 - 0.00068 19.2 2.1 0.011 15.4 0.2 2.5 2 0 0 2 2 2 1 NADH pyrophosphatase zinc ribbon domain Rhodanese_C PF12368.8 KFX91078.1 - 0.034 14.5 0.7 0.061 13.7 0.7 1.3 1 0 0 1 1 1 0 Rhodanase C-terminal WRNPLPNID PF15017.6 KFX91078.1 - 6.5 7.7 16.1 1 10.3 9.7 2.8 2 1 0 2 2 2 0 Putative WW-binding domain and destruction box Gly_transf_sug PF04488.15 KFX91079.1 - 4e-13 49.8 0.1 7.2e-13 49.0 0.1 1.4 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Haspin_kinase PF12330.8 KFX91081.1 - 3.6e-34 118.3 0.0 5.2e-34 117.8 0.0 1.1 1 0 0 1 1 1 1 Haspin like kinase domain PQ-loop PF04193.14 KFX91093.1 - 7.8e-20 70.4 10.5 1.1e-14 53.9 1.9 3.0 3 0 0 3 3 3 2 PQ loop repeat Dynamin_N PF00350.23 KFX91094.1 - 1.3e-42 145.7 0.0 2.9e-42 144.6 0.0 1.6 1 0 0 1 1 1 1 Dynamin family Dynamin_M PF01031.20 KFX91094.1 - 6.2e-14 51.9 0.0 7.7e-12 45.0 0.0 2.3 2 0 0 2 2 2 2 Dynamin central region MMR_HSR1 PF01926.23 KFX91094.1 - 7.3e-06 26.1 0.2 0.00016 21.8 0.0 2.9 2 1 0 2 2 2 1 50S ribosome-binding GTPase AAA_21 PF13304.6 KFX91094.1 - 0.049 13.4 0.0 0.097 12.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 KFX91094.1 - 0.097 12.4 0.4 0.23 11.1 0.1 1.7 2 0 0 2 2 2 0 AAA ATPase domain AAA_16 PF13191.6 KFX91094.1 - 0.37 11.1 0.1 0.37 11.1 0.1 2.9 3 1 0 3 3 3 0 AAA ATPase domain PALP PF00291.25 KFX91098.1 - 7.9e-48 163.4 0.1 9.9e-48 163.0 0.1 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme LPMO_10 PF03067.15 KFX91099.1 - 4.2e-10 40.6 0.2 6.7e-10 39.9 0.2 1.4 1 1 0 1 1 1 1 Lytic polysaccharide mono-oxygenase, cellulose-degrading 2-Hacid_dh_C PF02826.19 KFX91106.1 - 2.9e-54 183.1 0.0 4e-54 182.7 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 KFX91106.1 - 9.7e-18 64.1 0.0 1.2e-17 63.9 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 KFX91106.1 - 0.00028 21.1 0.3 0.00046 20.4 0.3 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase SUZ PF12752.7 KFX91108.1 - 1.3e-06 29.1 1.6 1.3e-06 29.1 1.6 3.4 2 1 0 2 2 2 1 SUZ domain Fe_hyd_lg_C PF02906.14 KFX91109.1 - 1.7e-56 191.6 0.0 3.4e-56 190.7 0.0 1.5 1 1 0 1 1 1 1 Iron only hydrogenase large subunit, C-terminal domain Ost5 PF05251.12 KFX91110.1 - 1.4 9.2 7.0 0.27 11.5 1.2 2.2 2 0 0 2 2 2 0 Oligosaccharyltransferase subunit 5 EMP24_GP25L PF01105.24 KFX91111.1 - 3e-36 125.1 0.0 3.3e-36 124.9 0.0 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD ACT_3 PF10000.9 KFX91111.1 - 0.093 12.7 0.0 0.2 11.6 0.0 1.5 1 0 0 1 1 1 0 ACT domain DUF1627 PF07789.12 KFX91111.1 - 0.17 11.6 0.0 0.2 11.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1627) Arf PF00025.21 KFX91112.1 - 3.1e-76 254.7 0.1 4.3e-76 254.3 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 KFX91112.1 - 6.2e-14 52.2 0.0 9.5e-14 51.6 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 KFX91112.1 - 1.6e-13 50.5 0.0 2.8e-13 49.7 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.22 KFX91112.1 - 1.7e-12 47.3 0.0 2.1e-12 47.0 0.0 1.1 1 0 0 1 1 1 1 Ras family G-alpha PF00503.20 KFX91112.1 - 4.1e-12 45.9 0.9 3.5e-09 36.3 0.2 2.2 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.12 KFX91112.1 - 4.8e-10 39.2 0.0 7.5e-10 38.6 0.0 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 KFX91112.1 - 1.2e-05 25.3 0.0 2e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.18 KFX91112.1 - 0.03 13.6 0.2 0.076 12.3 0.0 1.6 2 0 0 2 2 2 0 6-phosphofructo-2-kinase GST_C_2 PF13410.6 KFX91114.1 - 4.2e-08 33.1 0.2 8.9e-08 32.0 0.2 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 KFX91114.1 - 0.0014 18.8 0.0 0.0023 18.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain MazE_antitoxin PF04014.18 KFX91114.1 - 0.16 12.0 0.4 1.5 8.8 0.0 2.6 3 0 0 3 3 3 0 Antidote-toxin recognition MazE, bacterial antitoxin IMUP PF15761.5 KFX91117.1 - 0.0044 17.7 9.9 0.0044 17.7 9.9 2.6 1 1 1 2 2 2 1 Immortalisation up-regulated protein GREB1 PF15782.5 KFX91117.1 - 2.2 5.3 10.1 2.5 5.1 10.1 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer DnaJ PF00226.31 KFX91120.1 - 6.8e-10 38.9 1.2 3e-09 36.9 0.3 2.2 2 0 0 2 2 2 1 DnaJ domain Pkinase PF00069.25 KFX91123.1 - 7.9e-19 68.0 0.0 1e-10 41.5 0.0 2.0 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KFX91123.1 - 7.1e-09 35.3 0.0 0.0026 17.1 0.0 2.0 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 KFX91123.1 - 0.12 11.1 0.0 0.15 10.8 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase COG4 PF08318.12 KFX91124.1 - 7.3e-124 413.2 0.0 9.4e-124 412.8 0.0 1.1 1 0 0 1 1 1 1 COG4 transport protein Siva PF05458.12 KFX91127.1 - 0.011 15.4 3.5 0.014 15.1 3.5 1.1 1 0 0 1 1 1 0 Cd27 binding protein (Siva) YdjO PF14169.6 KFX91127.1 - 0.012 15.3 11.5 0.02 14.6 0.2 3.6 1 1 2 3 3 3 0 Cold-inducible protein YdjO DZR PF12773.7 KFX91127.1 - 0.16 12.0 3.9 2.1 8.5 3.9 2.3 1 1 0 1 1 1 0 Double zinc ribbon TF_Zn_Ribbon PF08271.12 KFX91127.1 - 2.3 7.8 9.1 5.9 6.5 0.2 3.1 2 1 0 2 2 2 0 TFIIB zinc-binding zf-RING_10 PF16685.5 KFX91127.1 - 3.5 7.8 6.6 1.1 9.5 2.7 2.2 2 1 0 2 2 2 0 zinc RING finger of MSL2 Myosin_head PF00063.21 KFX91128.1 - 7.5e-237 787.8 4.5 9e-237 787.6 4.5 1.1 1 0 0 1 1 1 1 Myosin head (motor domain) Myosin_TH1 PF06017.13 KFX91128.1 - 2.8e-48 164.1 0.0 4.8e-48 163.3 0.0 1.4 1 0 0 1 1 1 1 Unconventional myosin tail, actin- and lipid-binding SH3_1 PF00018.28 KFX91128.1 - 1.6e-15 56.4 0.3 3.3e-15 55.4 0.3 1.6 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 KFX91128.1 - 3.1e-11 42.8 0.0 6.6e-11 41.7 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.6 KFX91128.1 - 4.4e-11 42.5 0.0 1e-10 41.3 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain IQ PF00612.27 KFX91128.1 - 0.0039 16.9 8.4 0.59 10.1 0.2 2.7 2 0 0 2 2 2 2 IQ calmodulin-binding motif Hpr_kinase_C PF07475.12 KFX91128.1 - 0.02 14.4 0.1 7.5 6.0 0.0 2.5 2 0 0 2 2 2 0 HPr Serine kinase C-terminal domain AAA_22 PF13401.6 KFX91128.1 - 0.038 14.3 0.0 0.096 13.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 KFX91128.1 - 0.074 13.4 0.0 0.22 11.9 0.0 1.8 1 0 0 1 1 1 0 AAA ATPase domain NACHT PF05729.12 KFX91128.1 - 0.12 12.3 0.0 0.3 11.0 0.0 1.6 1 0 0 1 1 1 0 NACHT domain Ank_2 PF12796.7 KFX91129.1 - 3.8e-30 104.3 10.4 8.6e-14 51.9 0.6 2.6 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.30 KFX91129.1 - 1.8e-14 53.4 1.6 0.0024 18.3 0.1 3.9 3 0 0 3 3 3 3 Ankyrin repeat Ank_4 PF13637.6 KFX91129.1 - 5.2e-14 52.4 0.0 1.3e-07 32.0 0.0 3.0 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFX91129.1 - 4e-11 42.1 0.0 0.075 13.6 0.0 4.2 4 0 0 4 4 4 3 Ankyrin repeat Ank_5 PF13857.6 KFX91129.1 - 1.7e-06 28.2 0.6 0.0083 16.4 0.1 3.4 1 1 2 3 3 3 3 Ankyrin repeats (many copies) DUF676 PF05057.14 KFX91129.1 - 0.0042 16.6 0.0 0.0071 15.9 0.0 1.4 1 0 0 1 1 1 1 Putative serine esterase (DUF676) FAD_binding_8 PF08022.12 KFX91130.1 - 9.2e-22 77.2 0.0 1.8e-21 76.3 0.0 1.5 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.12 KFX91130.1 - 1e-20 74.4 0.0 1.7e-20 73.7 0.0 1.3 1 0 0 1 1 1 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.19 KFX91130.1 - 5.4e-19 68.5 9.3 5.4e-19 68.5 9.3 1.9 1 1 1 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_6 PF00970.24 KFX91130.1 - 0.0039 17.5 0.0 0.0081 16.5 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain F-box-like PF12937.7 KFX91131.1 - 0.0014 18.5 0.3 0.96 9.4 0.1 2.4 2 0 0 2 2 2 2 F-box-like F-box-like_2 PF13013.6 KFX91131.1 - 0.027 14.4 0.2 0.083 12.9 0.2 1.8 1 1 0 1 1 1 0 F-box-like domain AhpC-TSA PF00578.21 KFX91142.1 - 7.3e-25 87.3 0.0 1e-24 86.8 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 KFX91142.1 - 3.3e-15 56.1 0.0 4.6e-15 55.6 0.0 1.2 1 0 0 1 1 1 1 Redoxin AhpC-TSA_2 PF13911.6 KFX91142.1 - 0.00015 21.8 0.0 0.0011 19.0 0.0 2.0 1 1 1 2 2 2 1 AhpC/TSA antioxidant enzyme Vps51 PF08700.11 KFX91143.1 - 3e-10 40.0 0.0 2e-09 37.4 0.0 2.3 2 0 0 2 2 2 1 Vps51/Vps67 TetR_C_11 PF16859.5 KFX91143.1 - 0.015 15.6 5.7 0.054 13.8 4.2 2.8 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain UCR_Fe-S_N PF10399.9 KFX91143.1 - 0.15 11.4 0.2 0.37 10.2 0.2 1.7 1 0 0 1 1 1 0 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal Nexin_C PF08628.12 KFX91143.1 - 0.17 12.5 0.6 0.6 10.7 0.6 1.9 1 0 0 1 1 1 0 Sorting nexin C terminal PKcGMP_CC PF16808.5 KFX91143.1 - 0.38 10.7 3.3 9 6.2 0.3 3.0 2 0 0 2 2 2 0 Coiled-coil N-terminus of cGMP-dependent protein kinase BTB PF00651.31 KFX91144.1 - 2.1e-10 40.8 0.0 6.9e-10 39.1 0.0 1.9 1 1 0 1 1 1 1 BTB/POZ domain Glyco_hydro_92 PF07971.12 KFX91144.1 - 0.014 14.3 0.0 0.019 13.9 0.0 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 92 Pro_isomerase PF00160.21 KFX91145.1 - 2.1e-47 161.3 0.1 3.2e-47 160.7 0.1 1.3 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD TPR_2 PF07719.17 KFX91145.1 - 2.1e-05 24.3 3.9 0.001 19.0 0.5 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.28 KFX91145.1 - 0.006 16.4 3.3 0.0092 15.8 0.2 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.6 KFX91145.1 - 0.12 12.6 0.1 0.4 11.0 0.1 1.9 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_14 PF13428.6 KFX91145.1 - 2.1 9.4 5.5 3.5 8.7 3.0 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat Hex_IIIa PF02455.16 KFX91147.1 - 0.22 10.2 0.0 0.27 10.0 0.0 1.1 1 0 0 1 1 1 0 Hexon-associated protein (IIIa) BP28CT PF08146.12 KFX91148.1 - 3.3e-39 134.3 1.9 6.5e-39 133.3 0.2 2.6 2 0 0 2 2 2 1 BP28CT (NUC211) domain U3snoRNP10 PF12397.8 KFX91148.1 - 7.3e-28 97.2 3.8 2.3e-27 95.6 0.0 4.1 3 0 0 3 3 3 1 U3 small nucleolar RNA-associated protein 10 HEAT PF02985.22 KFX91148.1 - 7.5e-05 22.7 6.5 0.22 11.9 0.1 6.1 5 0 0 5 5 5 2 HEAT repeat EF-hand_4 PF12763.7 KFX91148.1 - 0.019 14.9 0.0 0.057 13.4 0.0 1.7 1 0 0 1 1 1 0 Cytoskeletal-regulatory complex EF hand HEAT_2 PF13646.6 KFX91148.1 - 0.21 12.0 18.0 0.23 11.9 2.2 6.1 5 1 0 5 5 5 0 HEAT repeats HEAT_EZ PF13513.6 KFX91148.1 - 0.32 11.5 11.4 4.9 7.8 0.1 6.5 4 2 0 4 4 4 0 HEAT-like repeat DHBP_synthase PF00926.19 KFX91158.1 - 1e-19 70.8 0.1 1.2e-19 70.6 0.1 1.1 1 0 0 1 1 1 1 3,4-dihydroxy-2-butanone 4-phosphate synthase SDH_alpha PF03313.15 KFX91158.1 - 0.09 12.4 0.2 0.14 11.8 0.2 1.2 1 0 0 1 1 1 0 Serine dehydratase alpha chain Cellulase PF00150.18 KFX91159.1 - 1e-19 71.1 3.0 1.2e-19 70.9 2.3 1.4 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) CBM_1 PF00734.18 KFX91159.1 - 1.4e-12 47.3 13.2 3.5e-12 46.0 13.2 1.8 1 0 0 1 1 1 1 Fungal cellulose binding domain DNMT1-RFD PF12047.8 KFX91159.1 - 0.00029 20.9 0.7 0.0024 17.9 0.2 2.1 2 0 0 2 2 2 1 Cytosine specific DNA methyltransferase replication foci domain Glyco_hydro_2_C PF02836.17 KFX91159.1 - 0.00034 19.8 0.0 0.00052 19.2 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain DUF1643 PF07799.12 KFX91159.1 - 0.0018 18.5 0.2 0.0037 17.4 0.2 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1643) Glyco_hydro_42 PF02449.15 KFX91159.1 - 0.024 14.0 0.1 0.046 13.1 0.1 1.4 1 0 0 1 1 1 0 Beta-galactosidase adh_short_C2 PF13561.6 KFX91160.1 - 3.1e-50 170.9 0.4 3.8e-50 170.6 0.4 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KFX91160.1 - 5.3e-41 140.2 0.3 6.5e-41 139.9 0.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KFX91160.1 - 3e-09 37.0 0.4 4e-09 36.6 0.4 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KFX91160.1 - 0.013 14.9 0.2 0.024 14.1 0.2 1.5 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Zn_clus PF00172.18 KFX91161.1 - 1.3e-07 31.6 10.9 2.3e-07 30.8 10.9 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pox_A_type_inc PF04508.12 KFX91161.1 - 0.0014 18.4 3.4 0.0034 17.2 3.4 1.7 1 0 0 1 1 1 1 Viral A-type inclusion protein repeat Oxidored_FMN PF00724.20 KFX91162.1 - 7.7e-93 311.5 0.0 9e-93 311.2 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family ADH_zinc_N PF00107.26 KFX91164.1 - 7.9e-16 58.2 0.0 1.5e-15 57.4 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KFX91164.1 - 1.9e-08 34.1 0.1 0.002 18.0 0.0 2.7 1 1 1 2 2 2 2 Alcohol dehydrogenase GroES-like domain 2-Hacid_dh_C PF02826.19 KFX91164.1 - 0.0031 16.9 0.0 0.0054 16.1 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ELFV_dehydrog PF00208.21 KFX91164.1 - 0.12 12.0 0.0 0.2 11.3 0.0 1.3 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase PNGaseA PF12222.8 KFX91165.1 - 3.1e-161 537.1 0.1 4.2e-161 536.6 0.1 1.0 1 0 0 1 1 1 1 Peptide N-acetyl-beta-D-glucosaminyl asparaginase amidase A RNA_pol_Rpb1_1 PF04997.12 KFX91170.1 - 4.8e-41 141.1 0.8 5.5e-41 140.9 0.8 1.0 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 PPR_2 PF13041.6 KFX91171.1 - 8.1e-12 45.2 0.1 5.9e-05 23.2 0.0 3.9 4 1 1 5 5 5 2 PPR repeat family PPR PF01535.20 KFX91171.1 - 0.0021 18.2 0.7 7.1 7.1 0.0 3.9 4 0 0 4 4 4 2 PPR repeat PPR_3 PF13812.6 KFX91171.1 - 0.013 15.5 0.0 4.6 7.4 0.0 3.4 2 1 1 3 3 3 0 Pentatricopeptide repeat domain KH_1 PF00013.29 KFX91171.1 - 0.093 12.6 0.0 0.18 11.7 0.0 1.5 1 0 0 1 1 1 0 KH domain Peptidase_M20 PF01546.28 KFX91172.1 - 3.9e-33 114.9 0.0 5.3e-33 114.5 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 KFX91172.1 - 3.5e-14 52.6 0.0 6.4e-14 51.8 0.0 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 KFX91172.1 - 0.066 12.9 0.0 0.15 11.7 0.0 1.6 1 0 0 1 1 1 0 Peptidase family M28 Peptidase_M1 PF01433.20 KFX91173.1 - 2.2e-43 148.3 0.9 3.1e-43 147.9 0.9 1.2 1 0 0 1 1 1 1 Peptidase family M1 domain Leuk-A4-hydro_C PF09127.11 KFX91173.1 - 4.5e-35 120.1 0.0 9.2e-35 119.1 0.0 1.6 1 0 0 1 1 1 1 Leukotriene A4 hydrolase, C-terminal Peptidase_M1_N PF17900.1 KFX91173.1 - 2e-29 103.1 0.0 3e-29 102.6 0.0 1.2 1 0 0 1 1 1 1 Peptidase M1 N-terminal domain COX5A PF02284.16 KFX91173.1 - 0.22 11.5 0.2 0.48 10.5 0.2 1.5 1 0 0 1 1 1 0 Cytochrome c oxidase subunit Va Peptidase_M61 PF05299.12 KFX91173.1 - 0.24 11.8 2.4 3.7 8.0 2.4 2.4 1 1 0 1 1 1 0 M61 glycyl aminopeptidase Uds1 PF15456.6 KFX91176.1 - 4.8e-33 114.1 4.2 4.8e-33 114.1 4.2 1.9 2 0 0 2 2 2 1 Up-regulated During Septation DUF812 PF05667.11 KFX91176.1 - 0.0017 17.3 0.1 0.0022 17.0 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF812) Bap31_Bap29_C PF18035.1 KFX91176.1 - 0.037 14.0 0.1 0.1 12.6 0.1 1.7 1 0 0 1 1 1 0 Bap31/Bap29 cytoplasmic coiled-coil domain Stathmin PF00836.19 KFX91176.1 - 0.039 13.9 0.5 0.2 11.6 0.5 2.2 1 0 0 1 1 1 0 Stathmin family Wbp11 PF09429.10 KFX91176.1 - 0.087 13.2 0.3 0.24 11.8 0.3 1.7 1 0 0 1 1 1 0 WW domain binding protein 11 Adap_comp_sub PF00928.21 KFX91177.1 - 6.8e-64 215.8 0.0 8.3e-64 215.5 0.0 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 KFX91177.1 - 0.02 14.8 0.0 0.032 14.1 0.0 1.2 1 0 0 1 1 1 0 Clathrin adaptor complex small chain LRIF1 PF15741.5 KFX91177.1 - 0.068 11.7 0.2 0.1 11.1 0.2 1.1 1 0 0 1 1 1 0 Ligand-dependent nuclear receptor-interacting factor 1 DUF4536 PF15055.6 KFX91178.1 - 0.00024 21.3 5.8 0.0019 18.4 5.9 2.2 1 1 1 2 2 2 1 Domain of unknown function (DUF4536) ECR1_N PF14382.6 KFX91179.1 - 4e-16 58.5 0.7 1.2e-15 57.0 0.7 1.9 1 0 0 1 1 1 1 Exosome complex exonuclease RRP4 N-terminal region KH_6 PF15985.5 KFX91179.1 - 4e-06 27.1 0.6 8.3e-06 26.1 0.6 1.5 1 0 0 1 1 1 1 KH domain DUF4588 PF15251.6 KFX91180.1 - 5.8e-06 26.2 0.2 1.1e-05 25.3 0.2 1.5 1 1 0 1 1 1 1 Domain of unknown function (DUF4588) SNF2_N PF00176.23 KFX91181.1 - 1.9e-75 253.8 0.1 4.1e-75 252.7 0.1 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain SLIDE PF09111.10 KFX91181.1 - 1.6e-41 140.9 4.6 4e-41 139.6 2.3 2.6 2 0 0 2 2 2 1 SLIDE HAND PF09110.11 KFX91181.1 - 2.7e-38 131.1 0.9 2.7e-38 131.1 0.9 5.0 5 0 0 5 5 5 1 HAND Helicase_C PF00271.31 KFX91181.1 - 7.1e-19 68.2 0.3 1e-17 64.5 0.0 3.0 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 KFX91181.1 - 1.6e-11 44.5 0.0 9.7e-11 42.0 0.0 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Myb_DNA-binding PF00249.31 KFX91181.1 - 1.7e-05 24.9 0.0 0.0032 17.6 0.0 3.0 2 0 0 2 2 2 1 Myb-like DNA-binding domain DEAD PF00270.29 KFX91181.1 - 9.6e-05 22.2 0.0 0.0003 20.6 0.0 1.9 1 0 0 1 1 1 1 DEAD/DEAH box helicase SWI2_SNF2 PF18766.1 KFX91181.1 - 0.00021 21.1 0.0 0.00066 19.4 0.0 1.9 1 0 0 1 1 1 1 SWI2/SNF2 ATPase HDA2-3 PF11496.8 KFX91181.1 - 0.0008 18.7 0.0 0.0035 16.5 0.0 2.1 1 0 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 DEAD_2 PF06733.15 KFX91181.1 - 0.062 12.9 0.0 0.14 11.7 0.0 1.5 1 0 0 1 1 1 0 DEAD_2 AAA_14 PF13173.6 KFX91181.1 - 0.11 12.6 0.0 0.39 10.7 0.0 2.0 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 KFX91181.1 - 0.19 12.0 0.4 1.7 8.9 0.1 2.8 2 0 0 2 2 2 0 AAA domain Zn_clus PF00172.18 KFX91182.1 - 0.014 15.5 10.7 0.026 14.7 10.7 1.4 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain EHN PF06441.12 KFX91183.1 - 1.2e-27 96.4 0.4 2e-27 95.7 0.4 1.3 1 0 0 1 1 1 1 Epoxide hydrolase N terminus Abhydrolase_1 PF00561.20 KFX91183.1 - 1.2e-11 44.7 0.1 3.1e-11 43.4 0.1 1.6 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KFX91183.1 - 0.028 15.0 3.7 0.15 12.6 3.7 2.2 1 1 0 1 1 1 0 Alpha/beta hydrolase family DUF5490 PF17593.2 KFX91183.1 - 0.13 12.2 0.1 0.26 11.3 0.1 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5490) DJ-1_PfpI PF01965.24 KFX91184.1 - 8.3e-09 35.5 0.0 1.1e-08 35.1 0.0 1.2 1 0 0 1 1 1 1 DJ-1/PfpI family MFS_1 PF07690.16 KFX91185.1 - 1.3e-31 109.8 37.2 1.3e-31 109.8 37.2 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily Catalase PF00199.19 KFX91186.1 - 7.7e-178 591.4 0.3 9.1e-178 591.2 0.3 1.0 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.12 KFX91186.1 - 7.3e-11 42.1 0.0 2.1e-10 40.6 0.0 1.9 1 0 0 1 1 1 1 Catalase-related immune-responsive Gln_amidase PF15644.6 KFX91186.1 - 0.038 15.0 0.0 1.5 9.8 0.0 2.4 2 0 0 2 2 2 0 Papain fold toxin 1, glutamine deamidase Fungal_trans PF04082.18 KFX91187.1 - 1.8e-11 43.6 0.1 3.2e-11 42.8 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KFX91187.1 - 1.4e-08 34.7 11.6 2.7e-08 33.8 11.6 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain GMC_oxred_N PF00732.19 KFX91188.1 - 1.5e-51 175.6 0.0 1.9e-51 175.2 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KFX91188.1 - 5.6e-33 114.5 0.0 9e-33 113.8 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 KFX91188.1 - 0.00011 21.4 1.5 0.26 10.3 1.2 2.1 2 0 0 2 2 2 2 FAD binding domain Pyr_redox_3 PF13738.6 KFX91188.1 - 0.003 16.9 0.9 0.29 10.3 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KFX91188.1 - 0.014 15.0 0.0 0.026 14.1 0.0 1.5 1 0 0 1 1 1 0 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KFX91188.1 - 0.02 14.1 0.1 0.062 12.5 0.1 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 KFX91188.1 - 0.025 13.5 0.3 0.034 13.0 0.3 1.2 1 0 0 1 1 1 0 Tryptophan halogenase Lycopene_cycl PF05834.12 KFX91188.1 - 0.031 13.3 0.0 0.053 12.6 0.0 1.4 1 0 0 1 1 1 0 Lycopene cyclase protein NAD_binding_8 PF13450.6 KFX91188.1 - 0.034 14.4 0.5 0.077 13.2 0.5 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 KFX91188.1 - 0.13 11.5 0.5 0.24 10.6 0.1 1.6 2 0 0 2 2 2 0 Thi4 family Glyco_hydro_75 PF07335.11 KFX91199.1 - 5.8e-65 218.5 0.7 7.3e-65 218.2 0.7 1.1 1 0 0 1 1 1 1 Fungal chitosanase of glycosyl hydrolase group 75 SRP1_TIP1 PF00660.17 KFX91199.1 - 0.19 11.8 0.0 0.45 10.6 0.0 1.6 2 0 0 2 2 2 0 Seripauperin and TIP1 family Pectate_lyase_3 PF12708.7 KFX91200.1 - 1.6e-49 168.6 22.2 3.6e-42 144.6 9.8 2.9 3 1 0 3 3 3 2 Pectate lyase superfamily protein End_N_terminal PF12218.8 KFX91200.1 - 0.015 15.0 2.0 0.12 12.1 0.1 2.7 2 0 0 2 2 2 0 N terminal extension of bacteriophage endosialidase Sugar_tr PF00083.24 KFX91201.1 - 3.8e-81 273.3 21.9 4.4e-81 273.1 21.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KFX91201.1 - 3e-29 102.1 16.6 3e-29 102.1 16.6 1.4 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 KFX91201.1 - 0.0008 17.8 3.0 0.016 13.5 1.6 2.3 1 1 1 2 2 2 2 Organic Anion Transporter Polypeptide (OATP) family Pox_A14 PF05767.12 KFX91201.1 - 0.036 14.2 0.7 0.2 11.8 0.7 2.3 1 0 0 1 1 1 0 Poxvirus virion envelope protein A14 EntA_Immun PF08951.10 KFX91202.1 - 0.035 14.5 0.4 0.088 13.2 0.4 1.7 1 0 0 1 1 1 0 Enterocin A Immunity PreAtp-grasp PF18604.1 KFX91202.1 - 0.093 12.4 0.0 0.18 11.5 0.0 1.4 1 0 0 1 1 1 0 Pre ATP-grasp domain RRM_1 PF00076.22 KFX91203.1 - 4.7e-44 148.1 0.0 8.7e-13 47.9 0.0 4.5 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KFX91203.1 - 1.2e-36 124.4 0.0 5.6e-28 96.6 0.0 4.5 4 1 0 4 4 4 2 Occluded RNA-recognition motif RRM_5 PF13893.6 KFX91203.1 - 0.00018 21.1 0.0 0.2 11.3 0.0 3.4 3 0 0 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 KFX91203.1 - 0.00021 21.2 0.0 0.22 11.6 0.0 3.1 3 0 0 3 3 3 2 Nup53/35/40-type RNA recognition motif RL PF17797.1 KFX91203.1 - 0.0021 17.9 0.0 0.098 12.6 0.0 2.8 2 0 0 2 2 2 1 RL domain RRM_Rrp7 PF17799.1 KFX91203.1 - 0.18 11.6 0.1 0.95 9.3 0.0 2.1 2 0 0 2 2 2 0 Rrp7 RRM-like N-terminal domain RRM_3 PF08777.11 KFX91203.1 - 0.22 11.6 1.4 1.4 9.0 0.1 2.9 3 0 0 3 3 3 0 RNA binding motif TPR_14 PF13428.6 KFX91203.1 - 0.25 12.3 11.7 8.3 7.5 0.1 6.1 7 0 0 7 7 7 0 Tetratricopeptide repeat Ribosomal_L22 PF00237.19 KFX91204.1 - 7.7e-29 100.0 0.1 1.3e-28 99.2 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e DAO PF01266.24 KFX91205.1 - 4.2e-29 102.2 0.9 5.7e-29 101.8 0.9 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KFX91205.1 - 0.083 13.1 0.2 0.083 13.1 0.2 1.8 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain DUF3425 PF11905.8 KFX91206.1 - 1.4e-17 63.8 0.1 3.3e-17 62.6 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) PI31_Prot_N PF11566.8 KFX91214.1 - 2.1e-62 209.8 0.0 3.5e-62 209.0 0.0 1.4 1 0 0 1 1 1 1 PI31 proteasome regulator N-terminal adh_short PF00106.25 KFX91214.1 - 6.2e-53 179.2 0.1 1.3e-52 178.1 0.1 1.5 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KFX91214.1 - 1.1e-34 120.1 0.1 1.9e-34 119.3 0.1 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DHR10 PF18595.1 KFX91214.1 - 3.2e-19 69.1 18.8 3.2e-19 69.1 18.8 2.6 2 0 0 2 2 2 1 Designed helical repeat protein 10 domain DUF4267 PF14087.6 KFX91214.1 - 1.3e-18 67.1 4.7 2.5e-18 66.2 4.7 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4267) PI31_Prot_C PF08577.11 KFX91214.1 - 3.3e-17 63.4 16.8 3.3e-17 63.4 16.8 3.1 3 0 0 3 3 3 1 PI31 proteasome regulator KR PF08659.10 KFX91214.1 - 4.8e-12 46.1 0.0 9.7e-12 45.2 0.0 1.5 1 0 0 1 1 1 1 KR domain Sacchrp_dh_NADP PF03435.18 KFX91214.1 - 0.24 11.7 0.6 0.46 10.7 0.1 1.8 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain DUF515 PF04415.12 KFX91214.1 - 0.41 9.0 4.4 0.81 8.0 4.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF515) BAF1_ABF1 PF04684.13 KFX91214.1 - 5.5 5.9 12.5 8 5.4 12.5 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor GATA PF00320.27 KFX91215.1 - 0.029 14.0 5.1 1.3 8.7 0.2 3.0 3 1 0 3 3 3 0 GATA zinc finger DUF936 PF06075.12 KFX91216.1 - 0.27 10.1 3.0 0.33 9.8 3.0 1.1 1 0 0 1 1 1 0 Plant protein of unknown function (DUF936) WD40 PF00400.32 KFX91225.1 - 2.6e-36 123.0 20.6 3e-07 31.0 0.1 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFX91225.1 - 5.3e-15 55.5 0.0 0.00019 21.6 0.1 4.6 2 2 1 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KFX91225.1 - 0.00016 21.6 0.0 0.11 12.4 0.0 2.7 1 1 2 3 3 3 2 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 KFX91225.1 - 0.00041 19.4 0.1 3.8 6.4 0.0 3.9 3 1 1 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 KFX91225.1 - 0.01 15.2 0.0 0.64 9.3 0.0 2.9 3 1 1 4 4 4 0 WD40-like domain Ank_2 PF12796.7 KFX91228.1 - 5.2e-21 75.0 0.1 9.5e-10 38.9 0.0 4.4 2 2 2 4 4 4 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KFX91228.1 - 2.8e-16 59.6 1.1 1.1e-06 29.0 0.1 6.2 6 1 1 7 7 7 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFX91228.1 - 5.5e-14 50.9 0.6 0.092 13.4 0.0 7.2 7 0 0 7 7 7 3 Ankyrin repeat Ank PF00023.30 KFX91228.1 - 1.8e-10 40.7 1.6 0.15 12.6 0.0 7.0 6 1 0 6 6 6 3 Ankyrin repeat Ank_5 PF13857.6 KFX91228.1 - 3.7e-09 36.7 7.3 0.34 11.3 0.0 7.3 6 2 1 7 7 7 3 Ankyrin repeats (many copies) Transketolase_N PF00456.21 KFX91229.1 - 3.4e-151 502.9 0.3 4.5e-151 502.5 0.3 1.1 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.24 KFX91229.1 - 8.3e-45 152.6 0.0 1.4e-44 151.9 0.0 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 KFX91229.1 - 3.7e-12 46.2 0.0 9.1e-12 45.0 0.0 1.7 1 0 0 1 1 1 1 Transketolase, C-terminal domain Beta_elim_lyase PF01212.21 KFX91229.1 - 0.045 13.0 0.1 0.077 12.3 0.1 1.3 1 0 0 1 1 1 0 Beta-eliminating lyase WD40 PF00400.32 KFX91236.1 - 0.0058 17.5 2.8 6.6 7.8 0.0 4.8 5 0 0 5 5 5 2 WD domain, G-beta repeat Isochorismatase PF00857.20 KFX91237.1 - 2.1e-28 99.7 0.0 4e-28 98.8 0.0 1.4 1 1 0 1 1 1 1 Isochorismatase family MARVEL PF01284.23 KFX91238.1 - 8.7e-05 22.6 11.3 0.00065 19.7 11.8 1.8 1 1 0 1 1 1 1 Membrane-associating domain LSM PF01423.22 KFX91249.1 - 1.1e-14 53.9 0.2 1.3e-14 53.7 0.2 1.1 1 0 0 1 1 1 1 LSM domain Hfq PF17209.3 KFX91249.1 - 0.00047 19.7 0.1 0.00069 19.2 0.1 1.3 1 0 0 1 1 1 1 Hfq protein AA_permease PF00324.21 KFX91250.1 - 1.4e-125 419.6 43.3 1.7e-125 419.3 43.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KFX91250.1 - 3.4e-28 98.6 47.6 4.6e-28 98.2 47.6 1.0 1 0 0 1 1 1 1 Amino acid permease DUF5427 PF10310.9 KFX91253.1 - 4.3e-176 586.5 0.0 5e-176 586.2 0.0 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF5427) Flu_M1_C PF08289.11 KFX91253.1 - 0.011 16.0 0.3 0.041 14.1 0.2 2.0 2 0 0 2 2 2 0 Influenza Matrix protein (M1) C-terminal domain Pkinase PF00069.25 KFX91254.1 - 3.3e-69 233.2 0.0 5.9e-69 232.4 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFX91254.1 - 2.7e-31 108.8 0.0 3.8e-30 105.0 0.0 2.4 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KFX91254.1 - 0.0083 16.1 0.1 0.13 12.2 0.0 2.5 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.6 KFX91254.1 - 0.0096 15.3 0.1 3.5 6.8 0.0 2.5 2 0 0 2 2 2 2 Kinase-like RIO1 PF01163.22 KFX91254.1 - 0.057 13.0 0.2 0.13 11.8 0.2 1.6 1 1 0 1 1 1 0 RIO1 family Pkinase_fungal PF17667.1 KFX91254.1 - 0.061 12.1 1.8 0.22 10.2 1.8 1.9 1 1 0 1 1 1 0 Fungal protein kinase Zn_clus PF00172.18 KFX91255.1 - 0.00015 21.8 10.6 0.00029 20.9 10.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SSP160 PF06933.11 KFX91255.1 - 0.048 11.9 0.1 0.083 11.1 0.1 1.3 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 MFS_1 PF07690.16 KFX91256.1 - 5.9e-19 68.2 26.4 1.2e-12 47.4 2.2 2.5 2 1 0 2 2 2 2 Major Facilitator Superfamily CFEM PF05730.11 KFX91258.1 - 7.6e-11 42.0 13.9 1.2e-10 41.4 13.9 1.3 1 0 0 1 1 1 1 CFEM domain GRIM-19 PF06212.12 KFX91260.1 - 9.3e-21 74.2 0.0 2.1e-20 73.0 0.0 1.6 1 1 0 1 1 1 1 GRIM-19 protein tRNA_m1G_MT PF01746.21 KFX91261.1 - 1.4e-28 100.0 0.0 3.1e-21 76.0 0.0 2.4 2 0 0 2 2 2 2 tRNA (Guanine-1)-methyltransferase Acetyltransf_1 PF00583.25 KFX91262.1 - 6.9e-07 29.5 0.1 1.2e-06 28.8 0.1 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KFX91262.1 - 2.3e-05 24.7 0.1 5e-05 23.6 0.1 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KFX91262.1 - 7.6e-05 22.6 0.0 0.00015 21.7 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KFX91262.1 - 0.0011 18.9 0.1 0.0021 18.0 0.1 1.5 1 0 0 1 1 1 1 FR47-like protein DUF3472 PF11958.8 KFX91263.1 - 0.0036 17.8 0.2 0.0053 17.2 0.2 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3472) Melibiase_2 PF16499.5 KFX91264.1 - 3.6e-57 193.7 1.0 5.9e-57 193.0 1.0 1.3 1 0 0 1 1 1 1 Alpha galactosidase A Melibiase_C PF17801.1 KFX91264.1 - 1.3e-12 47.6 0.3 1.3e-12 47.6 0.3 2.7 3 0 0 3 3 3 1 Alpha galactosidase C-terminal beta sandwich domain Ricin_B_lectin PF00652.22 KFX91264.1 - 3.3e-09 37.1 3.8 5.5e-09 36.4 3.8 1.3 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain Melibiase PF02065.18 KFX91264.1 - 0.077 11.9 0.0 0.12 11.3 0.0 1.2 1 0 0 1 1 1 0 Melibiase RicinB_lectin_2 PF14200.6 KFX91264.1 - 0.52 11.1 7.5 2 9.2 1.9 3.0 2 1 1 3 3 3 0 Ricin-type beta-trefoil lectin domain-like Fig1 PF12351.8 KFX91265.1 - 2.4e-55 187.4 5.9 2.4e-55 187.4 5.9 2.1 2 0 0 2 2 2 1 Ca2+ regulator and membrane fusion protein Fig1 SUR7 PF06687.12 KFX91265.1 - 3e-07 30.3 11.6 4.3e-07 29.8 11.6 1.2 1 0 0 1 1 1 1 SUR7/PalI family DUF1970 PF09301.10 KFX91265.1 - 0.0034 17.6 0.3 0.012 15.9 0.1 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF1970) DUF898 PF05987.13 KFX91265.1 - 0.095 11.7 12.6 0.25 10.3 12.5 1.7 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF898) DUF4969 PF16339.5 KFX91265.1 - 0.71 10.3 2.0 21 5.5 1.2 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4969) HSF_DNA-bind PF00447.17 KFX91266.1 - 8.8e-32 109.6 2.8 1.9e-31 108.5 2.8 1.6 1 0 0 1 1 1 1 HSF-type DNA-binding Response_reg PF00072.24 KFX91266.1 - 1.2e-20 73.8 0.0 2.8e-20 72.6 0.0 1.7 1 0 0 1 1 1 1 Response regulator receiver domain Ets PF00178.22 KFX91266.1 - 0.084 13.3 0.1 0.2 12.1 0.1 1.6 1 0 0 1 1 1 0 Ets-domain Gp58 PF07902.11 KFX91266.1 - 0.28 9.4 0.7 0.42 8.8 0.7 1.2 1 0 0 1 1 1 0 gp58-like protein Nucleo_P87 PF07267.11 KFX91266.1 - 8.8 5.0 12.9 1.7 7.4 8.8 1.7 2 0 0 2 2 2 0 Nucleopolyhedrovirus capsid protein P87 Cu-oxidase_2 PF07731.14 KFX91275.1 - 1.7e-36 125.0 0.9 2e-36 124.8 0.9 1.1 1 0 0 1 1 1 1 Multicopper oxidase HSP70 PF00012.20 KFX91277.1 - 1.3e-188 628.0 3.6 1.5e-188 627.8 3.6 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 KFX91277.1 - 1.6e-16 60.0 0.2 1.6e-15 56.8 0.1 2.0 2 0 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.16 KFX91277.1 - 5.1e-05 23.1 0.0 9.5e-05 22.2 0.0 1.4 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FtsA PF14450.6 KFX91277.1 - 0.014 15.8 0.6 6.7 7.2 0.1 2.8 2 1 0 2 2 2 0 Cell division protein FtsA BcrAD_BadFG PF01869.20 KFX91277.1 - 0.017 14.6 0.5 0.58 9.6 0.0 2.4 2 1 0 2 2 2 0 BadF/BadG/BcrA/BcrD ATPase family DDR PF08841.10 KFX91277.1 - 0.018 14.1 0.7 0.17 10.9 0.4 2.2 2 1 0 2 2 2 0 Diol dehydratase reactivase ATPase-like domain DUF1464 PF07318.12 KFX91277.1 - 0.052 12.7 0.0 0.11 11.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1464) DUF1894 PF08979.11 KFX91277.1 - 0.17 12.2 0.0 34 4.9 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF1894) Bromodomain PF00439.25 KFX91278.1 - 1.1e-29 102.3 0.8 3.8e-15 55.7 0.1 2.4 2 0 0 2 2 2 2 Bromodomain CKS PF01111.19 KFX91279.1 - 1.2e-34 118.3 1.1 1.6e-34 117.9 1.1 1.2 1 0 0 1 1 1 1 Cyclin-dependent kinase regulatory subunit ERO1 PF04137.15 KFX91281.1 - 4.9e-134 447.0 0.0 8.4e-134 446.2 0.0 1.4 1 0 0 1 1 1 1 Endoplasmic Reticulum Oxidoreductin 1 (ERO1) Pal1 PF08316.11 KFX91282.1 - 9.4e-07 29.7 0.0 2e-06 28.6 0.0 1.6 1 0 0 1 1 1 1 Pal1 cell morphology protein HVSL PF09749.9 KFX91283.1 - 4.2e-82 275.2 0.0 4.9e-82 275.0 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised conserved protein MFS_1 PF07690.16 KFX91286.1 - 4.7e-18 65.2 36.4 1.8e-17 63.3 34.0 2.8 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 KFX91286.1 - 7.7e-09 34.5 7.6 7.7e-09 34.5 7.6 1.8 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Phage_P2_GpU PF06995.11 KFX91287.1 - 0.045 13.3 0.0 0.063 12.9 0.0 1.2 1 0 0 1 1 1 0 Phage P2 GpU RTA1 PF04479.13 KFX91288.1 - 3.1e-65 219.7 12.2 3.1e-65 219.7 12.2 1.9 2 0 0 2 2 2 1 RTA1 like protein DUF1993 PF09351.10 KFX91289.1 - 8.6e-52 175.5 0.0 9.6e-52 175.4 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1993) FliG_M PF14841.6 KFX91289.1 - 0.093 13.0 0.1 0.21 11.8 0.1 1.7 1 1 0 1 1 1 0 FliG middle domain Oxidored_molyb PF00174.19 KFX91290.1 - 5.3e-58 195.4 0.0 8.7e-58 194.7 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain Mo-co_dimer PF03404.16 KFX91290.1 - 5.9e-28 97.6 0.7 1.1e-27 96.8 0.7 1.4 1 0 0 1 1 1 1 Mo-co oxidoreductase dimerisation domain Cyt-b5 PF00173.28 KFX91290.1 - 3.1e-10 40.1 0.0 5.6e-10 39.2 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Hus1 PF04005.12 KFX91303.1 - 2.3e-83 279.7 0.0 3.1e-83 279.3 0.0 1.1 1 0 0 1 1 1 1 Hus1-like protein E1-E2_ATPase PF00122.20 KFX91316.1 - 1.1e-36 126.1 22.5 1.1e-31 109.7 0.3 4.1 5 0 0 5 5 5 2 E1-E2 ATPase Cation_ATPase_C PF00689.21 KFX91316.1 - 2e-24 86.3 9.0 2e-24 86.3 9.0 2.3 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 KFX91316.1 - 6.8e-19 69.0 0.1 1.5e-17 64.6 0.1 2.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 KFX91316.1 - 2.3e-16 59.7 0.0 1.4e-15 57.2 0.0 2.2 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 KFX91316.1 - 1.5e-14 53.5 0.0 3.8e-14 52.1 0.0 1.8 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 KFX91316.1 - 0.00039 20.2 0.5 0.00088 19.1 0.4 1.6 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Ytp1 PF10355.9 KFX91317.1 - 3.6e-69 233.0 7.7 6.2e-69 232.3 7.7 1.3 1 0 0 1 1 1 1 Protein of unknown function (Ytp1) DUF2427 PF10348.9 KFX91317.1 - 1.1e-25 89.4 4.8 3.3e-25 87.9 1.4 2.6 2 0 0 2 2 2 1 Domain of unknown function (DUF2427) GAF PF01590.26 KFX91320.1 - 0.0021 18.7 0.0 0.0047 17.5 0.0 1.6 1 1 0 1 1 1 1 GAF domain HATPase_c PF02518.26 KFX91321.1 - 7.9e-24 84.3 0.0 1.7e-23 83.3 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 KFX91321.1 - 2.8e-15 56.4 0.0 7.4e-14 51.9 0.0 2.4 1 1 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.25 KFX91321.1 - 3.1e-07 30.3 0.0 8.7e-07 28.9 0.0 1.8 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain MEDS PF14417.6 KFX91321.1 - 2.5e-06 27.4 1.3 8.1e-05 22.5 0.7 2.9 2 1 0 2 2 2 1 MEDS: MEthanogen/methylotroph, DcmR Sensory domain HATPase_c_3 PF13589.6 KFX91321.1 - 0.15 11.9 0.0 0.32 10.8 0.0 1.5 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Spidroin_MaSp PF11260.8 KFX91321.1 - 6.5 7.1 7.6 6.1 7.2 0.0 3.7 5 0 0 5 5 5 0 Major ampullate spidroin 1 and 2 Ecl1 PF12855.7 KFX91322.1 - 3.2e-13 51.2 1.4 5.6e-13 50.4 1.4 1.3 1 0 0 1 1 1 1 ECL1/2/3 zinc binding proteins C1_1 PF00130.22 KFX91322.1 - 0.084 12.8 1.5 0.27 11.1 1.8 1.6 1 1 1 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) MFS_1 PF07690.16 KFX91323.1 - 4.8e-25 88.2 44.6 2.6e-19 69.4 13.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KFX91323.1 - 5.3e-12 45.4 0.2 5.3e-12 45.4 0.2 1.9 2 0 0 2 2 2 1 Sugar (and other) transporter MFS_1_like PF12832.7 KFX91323.1 - 0.0051 15.7 4.3 0.0051 15.7 4.3 2.5 2 2 0 2 2 2 1 MFS_1 like family RRM_Rrp7 PF17799.1 KFX91324.1 - 1.3e-21 77.0 0.0 2.1e-21 76.4 0.0 1.3 1 0 0 1 1 1 1 Rrp7 RRM-like N-terminal domain RRP7 PF12923.7 KFX91324.1 - 7e-16 58.4 1.7 7e-16 58.4 1.7 1.8 2 0 0 2 2 2 1 Ribosomal RNA-processing protein 7 (RRP7) C-terminal domain DUF5093 PF17011.5 KFX91324.1 - 0.024 14.9 0.0 0.068 13.5 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF5093) Rad51 PF08423.11 KFX91325.1 - 3.5e-112 373.8 0.0 4.4e-112 373.5 0.0 1.1 1 0 0 1 1 1 1 Rad51 RecA PF00154.21 KFX91325.1 - 1.4e-13 50.9 0.0 2.1e-13 50.3 0.0 1.3 1 0 0 1 1 1 1 recA bacterial DNA recombination protein ATPase PF06745.13 KFX91325.1 - 3.9e-07 29.6 0.0 1.1e-06 28.2 0.0 1.7 1 1 0 1 1 1 1 KaiC AAA_25 PF13481.6 KFX91325.1 - 5.2e-05 22.9 0.0 0.00012 21.7 0.0 1.6 1 1 0 1 1 1 1 AAA domain DnaB_C PF03796.15 KFX91325.1 - 0.0081 15.5 0.0 0.34 10.2 0.0 2.2 2 0 0 2 2 2 1 DnaB-like helicase C terminal domain HHH_5 PF14520.6 KFX91325.1 - 0.038 14.6 2.2 0.11 13.1 1.0 2.2 2 0 0 2 2 2 0 Helix-hairpin-helix domain RNA_pol_A_CTD PF03118.15 KFX91325.1 - 0.053 13.3 0.5 0.12 12.2 0.5 1.5 1 0 0 1 1 1 0 Bacterial RNA polymerase, alpha chain C terminal domain AAA PF00004.29 KFX91325.1 - 0.15 12.5 0.2 2 8.9 0.0 2.5 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) PAXNEB PF05625.11 KFX91325.1 - 0.16 11.1 0.8 4.1 6.5 0.2 2.4 2 2 0 2 2 2 0 PAXNEB protein zf-CCHC PF00098.23 KFX91326.1 - 4.7e-41 137.1 57.3 1.1e-07 31.6 2.5 7.3 7 0 0 7 7 7 7 Zinc knuckle zf-CCHC_5 PF14787.6 KFX91326.1 - 4.3e-08 32.7 42.6 0.0014 18.3 4.1 7.2 4 2 3 7 7 7 5 GAG-polyprotein viral zinc-finger zf-CCHC_4 PF14392.6 KFX91326.1 - 6.6e-08 32.2 45.7 0.014 15.1 1.0 7.5 8 0 0 8 8 8 6 Zinc knuckle zf-CCHC_3 PF13917.6 KFX91326.1 - 2e-05 24.5 41.8 0.7 9.9 0.4 7.1 4 2 2 6 6 6 5 Zinc knuckle Sporozoite_P67 PF05642.11 KFX91326.1 - 0.19 9.8 1.6 0.23 9.5 1.6 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen zf-CCHC_6 PF15288.6 KFX91326.1 - 5.3 7.0 44.3 0.25 11.2 2.2 6.8 6 1 1 7 7 7 0 Zinc knuckle FAD_binding_3 PF01494.19 KFX91327.1 - 1.5e-14 54.0 0.1 4.1e-07 29.6 0.0 3.1 2 1 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 KFX91327.1 - 2.5e-05 24.4 0.0 4.9e-05 23.5 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KFX91327.1 - 9.8e-05 21.7 0.0 0.00018 20.9 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KFX91327.1 - 0.0041 16.4 0.1 0.0077 15.5 0.1 1.3 1 0 0 1 1 1 1 Thi4 family AlaDh_PNT_C PF01262.21 KFX91327.1 - 0.081 12.2 0.1 0.13 11.5 0.1 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain DAO PF01266.24 KFX91327.1 - 0.17 11.4 0.6 0.35 10.4 0.4 1.6 2 0 0 2 2 2 0 FAD dependent oxidoreductase Sugar_tr PF00083.24 KFX91328.1 - 1.3e-76 258.3 13.7 1.5e-76 258.1 13.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KFX91328.1 - 4.2e-29 101.6 16.1 6e-29 101.1 16.1 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 KFX91328.1 - 0.00067 18.2 0.4 0.00067 18.2 0.4 1.9 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) MFS_2 PF13347.6 KFX91328.1 - 0.006 15.2 13.4 0.13 10.8 0.3 2.7 2 1 1 3 3 3 2 MFS/sugar transport protein MTP18 PF10558.9 KFX91329.1 - 8.6e-78 260.2 0.2 1e-77 259.9 0.2 1.1 1 0 0 1 1 1 1 Mitochondrial 18 KDa protein (MTP18) BatD PF13584.6 KFX91330.1 - 0.011 14.6 0.1 0.013 14.4 0.1 1.0 1 0 0 1 1 1 0 Oxygen tolerance ABC2_membrane_2 PF12679.7 KFX91330.1 - 0.18 11.1 1.2 0.21 10.8 1.2 1.1 1 0 0 1 1 1 0 ABC-2 family transporter protein Pex24p PF06398.11 KFX91330.1 - 0.39 9.7 1.3 2.8 6.8 0.2 2.0 2 0 0 2 2 2 0 Integral peroxisomal membrane peroxin Tfb5 PF06331.12 KFX91331.1 - 4.3e-24 84.3 0.2 4.7e-24 84.2 0.2 1.0 1 0 0 1 1 1 1 Transcription factor TFIIH complex subunit Tfb5 2OG-FeII_Oxy_2 PF13532.6 KFX91332.1 - 2e-29 103.2 0.0 7.9e-29 101.2 0.0 1.9 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily Isochorismatase PF00857.20 KFX91332.1 - 3.8e-23 82.6 0.0 2.6e-18 66.8 0.0 2.5 2 0 0 2 2 2 2 Isochorismatase family GST_C_2 PF13410.6 KFX91332.1 - 5.9e-08 32.6 0.7 1.3e-07 31.5 0.7 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KFX91332.1 - 2.1e-06 27.9 0.0 5e-06 26.6 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 KFX91332.1 - 7.1e-06 26.2 0.0 1.5e-05 25.1 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain ECH_1 PF00378.20 KFX91333.1 - 7.8e-43 146.6 0.3 2.4e-42 145.0 0.3 1.6 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KFX91333.1 - 2.6e-29 102.8 0.1 1.5e-27 97.0 0.0 2.0 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase zf-NOSIP PF15906.5 KFX91333.1 - 0.0039 17.3 0.1 0.0097 16.0 0.0 1.6 1 1 0 1 1 1 1 Zinc-finger of nitric oxide synthase-interacting protein Pkinase PF00069.25 KFX91336.1 - 1.5e-67 227.8 0.0 1.9e-67 227.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFX91336.1 - 1.4e-31 109.7 0.0 2e-31 109.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 KFX91336.1 - 0.00048 19.5 0.3 0.00084 18.8 0.3 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 KFX91336.1 - 0.0031 16.5 0.1 0.005 15.8 0.1 1.3 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 KFX91336.1 - 0.012 14.9 0.0 0.022 14.1 0.0 1.3 1 0 0 1 1 1 0 Kinase-like APH PF01636.23 KFX91336.1 - 0.032 14.1 0.0 0.056 13.4 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 KFX91336.1 - 0.071 12.2 0.0 0.11 11.5 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 RNA_pol_Rpb1_5 PF04998.17 KFX91338.1 - 9.8e-80 267.8 0.1 1.3e-79 267.4 0.1 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_3 PF04983.18 KFX91338.1 - 1.2e-38 132.5 0.0 2.5e-38 131.5 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.17 KFX91338.1 - 3.2e-29 101.0 0.2 8.8e-29 99.6 0.2 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 Phlebovirus_NSM PF07246.11 KFX91339.1 - 0.05 13.0 0.4 0.056 12.8 0.4 1.1 1 0 0 1 1 1 0 Phlebovirus nonstructural protein NS-M AA_permease_2 PF13520.6 KFX91341.1 - 6.1e-40 137.3 53.5 9e-40 136.8 53.5 1.2 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KFX91341.1 - 2.4e-08 33.0 44.6 3.9e-08 32.3 44.6 1.2 1 0 0 1 1 1 1 Amino acid permease Acetyltransf_7 PF13508.7 KFX91342.1 - 0.00016 22.0 0.0 0.00029 21.2 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 KFX91342.1 - 0.00026 21.0 0.0 0.72 9.9 0.0 2.2 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KFX91342.1 - 0.016 15.1 0.0 0.028 14.3 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KFX91342.1 - 0.12 12.6 0.0 0.18 12.0 0.0 1.6 1 1 0 1 1 1 0 Acetyltransferase (GNAT) family AA_permease_2 PF13520.6 KFX91344.1 - 9e-63 212.6 45.1 1.1e-62 212.3 45.1 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KFX91344.1 - 4e-32 111.4 35.6 5.4e-32 111.0 35.6 1.1 1 0 0 1 1 1 1 Amino acid permease MFS_1 PF07690.16 KFX91345.1 - 3e-07 29.7 18.8 3e-07 29.7 18.8 2.6 2 1 0 2 2 2 1 Major Facilitator Superfamily Pec_lyase_C PF00544.19 KFX91346.1 - 0.024 14.2 0.0 0.035 13.7 0.0 1.3 1 0 0 1 1 1 0 Pectate lyase FAD_binding_3 PF01494.19 KFX91347.1 - 7.1e-07 28.8 0.3 5.9e-06 25.8 0.3 2.0 1 1 0 1 1 1 1 FAD binding domain Orai-1 PF07856.12 KFX91347.1 - 0.19 11.4 0.0 0.27 10.9 0.0 1.2 1 0 0 1 1 1 0 Mediator of CRAC channel activity Pkr1 PF08636.10 KFX91348.1 - 6.6e-27 93.5 5.5 8e-27 93.2 5.5 1.1 1 0 0 1 1 1 1 ER protein Pkr1 Cys_Met_Meta_PP PF01053.20 KFX91353.1 - 1e-139 465.4 0.1 1.2e-139 465.2 0.1 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.17 KFX91353.1 - 1.5e-06 27.8 1.6 2.6e-06 27.0 1.6 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_1_2 PF00155.21 KFX91353.1 - 2.2e-06 27.1 0.3 3.4e-06 26.5 0.3 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 KFX91353.1 - 8.7e-06 24.9 0.6 1.5e-05 24.2 0.6 1.3 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 KFX91353.1 - 0.001 18.4 0.5 0.0027 17.0 0.4 1.7 1 1 0 1 1 1 1 Beta-eliminating lyase AOX PF01786.17 KFX91353.1 - 0.047 13.3 0.0 0.078 12.5 0.0 1.3 1 0 0 1 1 1 0 Alternative oxidase APG5 PF04106.12 KFX91364.1 - 1.6e-39 135.8 0.0 3.5e-39 134.7 0.0 1.5 1 1 0 1 1 1 1 Autophagy protein Apg5 Zn_clus PF00172.18 KFX91365.1 - 1.1e-06 28.7 9.7 1.9e-06 27.9 9.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pro_CA PF00484.19 KFX91368.1 - 1.6e-16 61.0 0.0 2e-16 60.7 0.0 1.1 1 0 0 1 1 1 1 Carbonic anhydrase Ribosomal_L7Ae PF01248.26 KFX91369.1 - 1.3e-21 76.1 0.7 2.3e-21 75.3 0.7 1.4 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family PNP_UDP_1 PF01048.20 KFX91373.1 - 0.0025 17.1 0.1 0.83 8.9 0.0 2.4 2 1 0 2 2 2 2 Phosphorylase superfamily Cu_bind_like PF02298.17 KFX91373.1 - 0.026 14.5 0.0 0.064 13.3 0.0 1.6 1 0 0 1 1 1 0 Plastocyanin-like domain SNF2_N PF00176.23 KFX91379.1 - 2.2e-66 224.0 0.3 1.3e-64 218.2 0.3 2.8 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KFX91379.1 - 9.7e-12 45.2 0.0 2.6e-11 43.9 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KFX91379.1 - 2.4e-06 27.6 0.0 4.9e-06 26.7 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit NAD_binding_10 PF13460.6 KFX91380.1 - 2.7e-07 30.7 0.2 3.4e-07 30.3 0.2 1.3 1 0 0 1 1 1 1 NAD(P)H-binding HIM1 PF08732.10 KFX91380.1 - 9.5e-07 28.5 0.0 2.9e-06 26.9 0.0 1.5 1 1 1 2 2 2 1 HIM1 NmrA PF05368.13 KFX91380.1 - 9.8e-07 28.6 0.0 1.3e-06 28.1 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family Epimerase PF01370.21 KFX91380.1 - 3e-05 23.6 0.0 3.7e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Semialdhyde_dh PF01118.24 KFX91380.1 - 0.01 16.3 0.0 0.024 15.1 0.0 1.6 1 1 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain 3Beta_HSD PF01073.19 KFX91380.1 - 0.011 14.8 0.0 0.04 12.9 0.0 2.0 1 1 1 2 2 2 0 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 KFX91380.1 - 0.026 13.7 0.0 1.1 8.3 0.0 2.1 2 0 0 2 2 2 0 Male sterility protein Polysacc_synt_2 PF02719.15 KFX91380.1 - 0.038 13.1 0.1 0.64 9.1 0.0 2.0 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein FAD_binding_1 PF00667.20 KFX91381.1 - 4e-63 213.0 0.0 7.7e-63 212.0 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain POR PF01558.18 KFX91381.1 - 5.6e-11 42.8 0.0 1.5e-10 41.5 0.0 1.6 1 0 0 1 1 1 1 Pyruvate ferredoxin/flavodoxin oxidoreductase NAD_binding_1 PF00175.21 KFX91381.1 - 6.3e-10 39.7 0.0 1.7e-09 38.3 0.0 1.7 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain PFOR_II PF17147.4 KFX91381.1 - 5.5e-07 29.8 0.2 2.2e-06 27.9 0.2 2.1 1 0 0 1 1 1 1 Pyruvate:ferredoxin oxidoreductase core domain II Transketolase_C PF02780.20 KFX91381.1 - 0.0043 16.9 0.1 0.017 15.0 0.1 2.0 1 0 0 1 1 1 1 Transketolase, C-terminal domain FAD_binding_6 PF00970.24 KFX91381.1 - 0.17 12.3 0.0 6.7 7.1 0.0 2.5 2 0 0 2 2 2 0 Oxidoreductase FAD-binding domain Oxidored_FMN PF00724.20 KFX91395.1 - 4.7e-50 170.8 0.0 5.8e-50 170.5 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family FMN_dh PF01070.18 KFX91395.1 - 0.0018 17.3 1.6 0.14 11.2 0.6 2.3 2 0 0 2 2 2 2 FMN-dependent dehydrogenase Dus PF01207.17 KFX91395.1 - 0.06 12.4 0.3 1.1 8.2 0.0 2.4 2 1 0 2 2 2 0 Dihydrouridine synthase (Dus) DUF1611_N PF17396.2 KFX91395.1 - 0.075 13.3 0.1 30 4.9 0.0 3.3 2 1 1 3 3 3 0 Domain of unknown function (DUF1611_N) Rossmann-like domain MMU163 PF17119.5 KFX91400.1 - 3.8e-49 167.1 7.1 7.6e-35 120.3 0.6 2.1 1 1 1 2 2 2 2 Mitochondrial protein up-regulated during meiosis Glyco_transf_90 PF05686.12 KFX91401.1 - 4.4e-06 25.9 0.0 0.00017 20.6 0.0 2.3 2 1 0 2 2 2 2 Glycosyl transferase family 90 ketoacyl-synt PF00109.26 KFX91402.1 - 3.3e-63 213.6 0.0 9.4e-63 212.1 0.0 1.9 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 KFX91402.1 - 1.6e-28 99.1 0.0 3.8e-28 97.9 0.0 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Acyl_transf_1 PF00698.21 KFX91402.1 - 1.5e-23 83.8 2.5 2.1e-23 83.3 0.6 2.0 2 0 0 2 2 2 1 Acyl transferase domain SAT PF16073.5 KFX91402.1 - 5.3e-16 59.1 4.0 5.3e-12 46.0 0.5 2.8 2 0 0 2 2 2 2 Starter unit:ACP transacylase in aflatoxin biosynthesis Thiolase_N PF00108.23 KFX91402.1 - 0.00012 21.5 0.1 0.00024 20.5 0.1 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain KAsynt_C_assoc PF16197.5 KFX91402.1 - 0.001 19.5 0.0 0.0024 18.3 0.0 1.7 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension Pik1 PF11522.8 KFX91416.1 - 1.7e-19 69.5 0.0 3.5e-19 68.5 0.0 1.5 1 0 0 1 1 1 1 Yeast phosphatidylinositol-4-OH kinase Pik1 PI3Ka PF00613.20 KFX91416.1 - 0.022 14.2 0.6 0.028 13.8 0.6 1.2 1 0 0 1 1 1 0 Phosphoinositide 3-kinase family, accessory domain (PIK domain) Pkinase_Tyr PF07714.17 KFX91417.1 - 2.4e-19 69.6 0.0 1.7e-17 63.5 0.0 2.1 1 1 0 2 2 2 1 Protein tyrosine kinase Pkinase PF00069.25 KFX91417.1 - 1.1e-16 61.0 0.0 3.6e-16 59.3 0.0 1.7 1 1 1 2 2 2 1 Protein kinase domain LRR_8 PF13855.6 KFX91417.1 - 9.9e-13 47.7 16.2 1.3e-06 28.1 1.4 3.6 2 1 2 4 4 4 4 Leucine rich repeat LRR_4 PF12799.7 KFX91417.1 - 1.3e-09 38.2 2.6 0.098 13.1 0.0 3.8 3 0 0 3 3 3 3 Leucine Rich repeats (2 copies) Kdo PF06293.14 KFX91417.1 - 7.3e-07 28.8 0.0 1.2e-06 28.0 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 KFX91417.1 - 0.00065 19.1 0.0 0.00098 18.5 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 KFX91417.1 - 0.0077 16.2 0.0 0.012 15.5 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family LRR_5 PF13306.6 KFX91417.1 - 0.0095 15.9 0.1 1.1 9.2 0.1 2.7 1 1 1 2 2 2 1 BspA type Leucine rich repeat region (6 copies) RIO1 PF01163.22 KFX91417.1 - 0.032 13.8 0.1 0.071 12.7 0.1 1.5 2 0 0 2 2 2 0 RIO1 family LRR_9 PF14580.6 KFX91417.1 - 0.23 10.9 0.2 0.86 9.1 0.2 1.9 1 1 0 1 1 1 0 Leucine-rich repeat LRR_1 PF00560.33 KFX91417.1 - 0.26 12.0 10.5 0.45 11.3 0.5 4.5 4 2 0 4 4 4 0 Leucine Rich Repeat FNIP PF05725.12 KFX91417.1 - 7.5 6.8 5.9 2 8.7 0.3 2.9 3 0 0 3 3 2 0 FNIP Repeat DUF1279 PF06916.13 KFX91436.1 - 1.1e-23 83.6 0.1 2.3e-23 82.5 0.1 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF1279) Chitin_bind_1 PF00187.19 KFX91439.1 - 1.3e-05 25.5 19.4 1.3e-05 25.5 19.4 2.4 3 0 0 3 3 3 1 Chitin recognition protein Glyco_hydro_61 PF03443.14 KFX91439.1 - 0.022 14.7 0.1 0.21 11.5 0.1 2.3 1 1 0 1 1 1 0 Glycosyl hydrolase family 61 6PGD PF00393.19 KFX91442.1 - 4.9e-86 288.7 0.0 5.9e-86 288.4 0.0 1.1 1 0 0 1 1 1 1 6-phosphogluconate dehydrogenase, C-terminal domain NAD_binding_2 PF03446.15 KFX91442.1 - 1.1e-33 116.6 0.0 2.1e-33 115.7 0.0 1.5 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase 3HCDH_N PF02737.18 KFX91442.1 - 3.8e-05 23.7 0.0 6.8e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_Gly3P_dh_N PF01210.23 KFX91442.1 - 0.0018 18.2 0.0 0.0037 17.3 0.0 1.5 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus ApbA PF02558.16 KFX91442.1 - 0.0026 17.4 0.0 0.0067 16.1 0.0 1.7 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA 2-Hacid_dh_C PF02826.19 KFX91442.1 - 0.0028 17.0 0.0 0.0068 15.8 0.0 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.14 KFX91442.1 - 0.0066 16.0 0.0 0.013 15.1 0.0 1.5 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Pyr_redox PF00070.27 KFX91442.1 - 0.0085 16.6 0.1 0.028 15.0 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase F420_oxidored PF03807.17 KFX91442.1 - 0.033 14.8 0.2 0.086 13.4 0.2 1.8 1 1 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent AP_endonuc_2 PF01261.24 KFX91443.1 - 3.8e-35 121.2 0.0 6.2e-35 120.5 0.0 1.3 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel adh_short PF00106.25 KFX91443.1 - 1.6e-15 57.0 0.3 2.4e-15 56.5 0.3 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KFX91443.1 - 1.6e-10 41.0 0.1 2.6e-10 40.2 0.1 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KFX91443.1 - 1e-05 25.6 0.2 1.7e-05 24.8 0.2 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KFX91443.1 - 0.024 14.1 0.1 0.06 12.8 0.1 1.6 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family ACT_3 PF10000.9 KFX91448.1 - 4e-21 74.7 0.6 5.5e-21 74.3 0.6 1.2 1 0 0 1 1 1 1 ACT domain ACT_7 PF13840.6 KFX91448.1 - 1.1e-12 47.5 0.1 1.6e-12 47.0 0.1 1.3 1 0 0 1 1 1 1 ACT domain Sugar_tr PF00083.24 KFX91449.1 - 1.9e-109 366.5 18.9 2.2e-109 366.3 18.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KFX91449.1 - 1.5e-24 86.6 26.6 1.5e-15 57.0 6.0 2.2 1 1 0 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 KFX91449.1 - 2.3e-05 23.1 17.6 0.00021 20.0 6.5 2.6 2 2 0 2 2 2 2 MFS/sugar transport protein DUF21 PF01595.20 KFX91449.1 - 1.9 8.2 5.0 2.1 8.0 3.5 1.9 1 1 0 1 1 1 0 Cyclin M transmembrane N-terminal domain Abhydrolase_1 PF00561.20 KFX91450.1 - 1.9e-17 63.7 0.0 4.6e-16 59.2 0.0 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KFX91450.1 - 1.3e-16 61.9 7.5 1.6e-15 58.3 7.5 2.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family NUDIX PF00293.28 KFX91450.1 - 2.6e-15 56.6 0.1 6.1e-15 55.4 0.1 1.6 1 0 0 1 1 1 1 NUDIX domain Hydrolase_4 PF12146.8 KFX91450.1 - 8.3e-14 51.4 0.0 2.6e-11 43.3 0.0 2.3 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Peptidase_S15 PF02129.18 KFX91450.1 - 0.047 13.3 0.0 7.4 6.1 0.0 2.3 2 0 0 2 2 2 0 X-Pro dipeptidyl-peptidase (S15 family) Chlorophyllase2 PF12740.7 KFX91450.1 - 0.11 11.4 0.0 0.18 10.7 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase enzyme Methyltransf_2 PF00891.18 KFX91451.1 - 1.2e-24 86.8 0.0 2.1e-24 86.0 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase domain Methyltransf_PK PF05891.12 KFX91451.1 - 0.044 13.3 0.0 0.077 12.5 0.0 1.4 1 0 0 1 1 1 0 AdoMet dependent proline di-methyltransferase Pyr_redox_2 PF07992.14 KFX91454.1 - 8.1e-19 68.0 0.2 3.6e-12 46.1 0.0 3.0 2 1 1 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KFX91454.1 - 1.4e-18 67.2 0.0 1.7e-16 60.4 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 KFX91454.1 - 5.8e-17 61.3 0.0 8.5e-16 57.5 0.0 2.1 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.6 KFX91454.1 - 1.6e-16 60.4 0.2 9.4e-13 48.0 0.0 3.0 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox PF00070.27 KFX91454.1 - 1.5e-10 41.5 0.1 0.00022 21.7 0.0 3.3 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.20 KFX91454.1 - 7.6e-10 39.0 0.0 5.6e-06 26.5 0.0 3.0 3 0 0 3 3 3 2 Shikimate / quinate 5-dehydrogenase F420_oxidored PF03807.17 KFX91454.1 - 6e-09 36.4 0.5 0.0019 18.7 0.1 3.4 3 0 0 3 3 3 2 NADP oxidoreductase coenzyme F420-dependent Lycopene_cycl PF05834.12 KFX91454.1 - 8.2e-07 28.4 0.3 0.0039 16.3 0.0 3.1 3 0 0 3 3 3 1 Lycopene cyclase protein NAD_binding_8 PF13450.6 KFX91454.1 - 9.7e-07 28.9 0.0 7e-05 23.0 0.0 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.19 KFX91454.1 - 7.5e-06 25.4 0.1 3.6e-05 23.2 0.0 2.0 2 0 0 2 2 2 1 FAD binding domain TrkA_N PF02254.18 KFX91454.1 - 1.3e-05 25.4 0.1 0.27 11.5 0.0 3.0 3 0 0 3 3 3 2 TrkA-N domain NAD_binding_9 PF13454.6 KFX91454.1 - 2.7e-05 24.2 1.8 0.39 10.7 0.0 3.6 3 1 1 4 4 4 2 FAD-NAD(P)-binding 2-Hacid_dh_C PF02826.19 KFX91454.1 - 3.8e-05 23.1 0.0 0.016 14.6 0.0 2.5 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain HI0933_like PF03486.14 KFX91454.1 - 0.00013 20.8 0.4 0.017 13.8 0.1 3.5 4 0 0 4 4 4 1 HI0933-like protein ThiF PF00899.21 KFX91454.1 - 0.00017 21.0 0.1 2.1 7.6 0.2 3.4 3 0 0 3 3 3 2 ThiF family FAD_binding_2 PF00890.24 KFX91454.1 - 0.00031 19.9 1.2 0.013 14.6 0.4 3.3 4 0 0 4 4 4 1 FAD binding domain AlaDh_PNT_C PF01262.21 KFX91454.1 - 0.00063 19.1 0.0 0.079 12.2 0.0 2.4 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_7 PF13241.6 KFX91454.1 - 0.0014 19.0 0.0 0.23 11.9 0.0 2.9 3 0 0 3 3 3 1 Putative NAD(P)-binding GIDA PF01134.22 KFX91454.1 - 0.0044 16.1 0.4 3.3 6.7 0.0 2.8 3 0 0 3 3 3 2 Glucose inhibited division protein A Thi4 PF01946.17 KFX91454.1 - 0.0078 15.5 0.7 1.1 8.4 0.1 2.9 3 0 0 3 3 3 1 Thi4 family DAO PF01266.24 KFX91454.1 - 0.0087 15.7 3.2 0.13 11.8 0.4 3.2 3 1 0 3 3 3 1 FAD dependent oxidoreductase 3HCDH_N PF02737.18 KFX91454.1 - 0.012 15.5 0.0 1.9 8.4 0.1 2.3 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain XdhC_C PF13478.6 KFX91454.1 - 0.017 15.6 0.0 0.14 12.6 0.0 2.3 2 0 0 2 2 2 0 XdhC Rossmann domain IlvN PF07991.12 KFX91454.1 - 0.018 14.7 0.2 3.5 7.2 0.0 2.3 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain ChlI PF13541.6 KFX91454.1 - 0.037 13.9 0.1 0.28 11.0 0.1 2.2 2 0 0 2 2 2 0 Subunit ChlI of Mg-chelatase Zn_clus PF00172.18 KFX91455.1 - 6.9e-09 35.7 5.8 1.4e-08 34.7 5.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CLZ PF16526.5 KFX91455.1 - 0.059 13.7 0.1 0.12 12.7 0.1 1.4 1 0 0 1 1 1 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels WXG100 PF06013.12 KFX91455.1 - 0.068 13.4 1.0 0.24 11.7 1.0 1.9 1 1 0 1 1 1 0 Proteins of 100 residues with WXG Ank_2 PF12796.7 KFX91471.1 - 1.1e-05 26.0 0.0 1.3e-05 25.7 0.0 1.2 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 KFX91471.1 - 0.00021 21.6 0.3 0.16 12.5 0.0 2.1 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.6 KFX91471.1 - 0.00036 20.8 0.0 0.00064 20.0 0.0 1.4 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_4 PF13637.6 KFX91471.1 - 0.02 15.4 0.0 0.025 15.2 0.0 1.3 1 0 0 1 1 1 0 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFX91471.1 - 0.021 15.3 0.1 11 7.0 0.0 2.1 2 0 0 2 2 2 0 Ankyrin repeat Methyltransf_31 PF13847.6 KFX91473.1 - 1.2e-20 73.8 0.0 1.6e-20 73.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KFX91473.1 - 8.4e-20 71.3 0.0 1.7e-19 70.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KFX91473.1 - 1.3e-15 57.8 0.0 2.4e-15 57.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KFX91473.1 - 1.5e-13 50.6 0.0 4.5e-13 49.1 0.0 1.8 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.6 KFX91473.1 - 4.7e-13 49.3 0.0 6.8e-13 48.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KFX91473.1 - 2.5e-12 47.4 0.1 8.3e-12 45.7 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain PCMT PF01135.19 KFX91473.1 - 5.2e-07 29.6 0.0 1.9e-06 27.8 0.0 1.8 1 1 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MTS PF05175.14 KFX91473.1 - 6e-07 29.2 0.0 1e-06 28.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain CMAS PF02353.20 KFX91473.1 - 1.8e-05 24.2 0.0 2.7e-05 23.6 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase FtsJ PF01728.19 KFX91473.1 - 0.00017 21.8 0.0 0.00031 20.9 0.0 1.5 1 1 0 1 1 1 1 FtsJ-like methyltransferase PrmA PF06325.13 KFX91473.1 - 0.0011 18.4 0.1 0.0019 17.7 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) DOT1 PF08123.13 KFX91473.1 - 0.0061 16.1 0.0 0.014 14.9 0.0 1.6 1 1 0 1 1 1 1 Histone methylation protein DOT1 UPF0020 PF01170.18 KFX91473.1 - 0.02 14.6 1.0 0.62 9.7 1.0 2.3 1 1 0 1 1 1 0 Putative RNA methylase family UPF0020 MTD PF01993.18 KFX91473.1 - 0.045 13.1 0.0 0.095 12.0 0.0 1.5 1 0 0 1 1 1 0 methylene-5,6,7,8-tetrahydromethanopterin dehydrogenase GCD14 PF08704.10 KFX91473.1 - 0.089 12.5 0.0 0.15 11.7 0.0 1.3 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit ADH_zinc_N PF00107.26 KFX91473.1 - 0.12 12.4 0.1 0.23 11.4 0.1 1.5 1 0 0 1 1 1 0 Zinc-binding dehydrogenase tRNA_U5-meth_tr PF05958.11 KFX91473.1 - 0.13 11.2 0.0 1.4 7.8 0.0 2.0 2 0 0 2 2 2 0 tRNA (Uracil-5-)-methyltransferase WD40 PF00400.32 KFX91483.1 - 6.7e-17 61.6 21.5 5.8e-05 23.8 0.6 6.2 5 2 0 5 5 5 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFX91483.1 - 4e-10 39.9 5.6 2e-05 24.8 0.1 3.5 2 2 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain TFIIIC_delta PF12657.7 KFX91483.1 - 0.0045 16.9 11.4 0.019 14.9 0.3 3.2 2 2 1 3 3 3 2 Transcription factor IIIC subunit delta N-term IKI3 PF04762.12 KFX91483.1 - 0.43 8.5 3.8 1.7 6.6 0.9 2.1 2 0 0 2 2 2 0 IKI3 family F-box-like PF12937.7 KFX91484.1 - 1.2e-05 25.1 0.2 2.6e-05 24.0 0.2 1.6 1 0 0 1 1 1 1 F-box-like DUF2738 PF10927.8 KFX91484.1 - 0.013 14.6 0.0 0.024 13.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2738) PD40 PF07676.12 KFX91485.1 - 0.13 12.2 0.8 7.7 6.6 0.0 3.6 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat RCC1_2 PF13540.6 KFX91485.1 - 0.17 11.7 1.5 16 5.5 0.1 3.0 3 0 0 3 3 3 0 Regulator of chromosome condensation (RCC1) repeat ABC_tran PF00005.27 KFX91488.1 - 1.3e-46 158.5 0.2 9.5e-22 78.0 0.0 3.1 3 0 0 3 3 2 2 ABC transporter ABC_tran_Xtn PF12848.7 KFX91488.1 - 9.4e-20 70.4 5.3 9.4e-20 70.4 5.3 3.4 4 0 0 4 4 3 1 ABC transporter AAA_21 PF13304.6 KFX91488.1 - 2.5e-15 57.1 11.2 0.00021 21.2 0.0 4.6 3 2 1 5 5 4 3 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 KFX91488.1 - 1.6e-11 44.1 3.2 0.00077 19.0 0.0 4.7 5 0 0 5 5 4 3 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 KFX91488.1 - 1.9e-07 31.5 0.0 0.0017 18.7 0.0 2.9 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.6 KFX91488.1 - 1e-05 25.1 0.3 0.18 11.6 0.0 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 KFX91488.1 - 1.1e-05 25.3 1.7 0.096 12.6 0.0 3.6 4 0 0 4 4 3 2 RsgA GTPase AAA_23 PF13476.6 KFX91488.1 - 1.3e-05 25.8 16.7 0.02 15.4 0.0 4.7 5 0 0 5 5 5 2 AAA domain AAA_18 PF13238.6 KFX91488.1 - 1.3e-05 25.7 0.8 0.44 11.1 0.0 3.6 4 0 0 4 4 3 2 AAA domain AAA_16 PF13191.6 KFX91488.1 - 1.5e-05 25.4 0.8 0.058 13.8 0.1 3.1 3 0 0 3 3 2 2 AAA ATPase domain AAA_33 PF13671.6 KFX91488.1 - 1.9e-05 24.9 0.1 0.4 10.8 0.0 3.0 2 0 0 2 2 2 2 AAA domain AAA_30 PF13604.6 KFX91488.1 - 4.7e-05 23.2 1.2 0.0067 16.2 0.0 3.3 4 1 1 5 5 4 1 AAA domain MMR_HSR1 PF01926.23 KFX91488.1 - 0.00011 22.2 3.6 0.13 12.3 0.1 3.3 3 1 0 3 3 3 2 50S ribosome-binding GTPase AAA_24 PF13479.6 KFX91488.1 - 0.00014 21.7 1.3 0.79 9.4 0.0 3.2 3 0 0 3 3 3 2 AAA domain AAA PF00004.29 KFX91488.1 - 0.00017 22.1 3.1 1 9.8 0.1 4.2 5 1 0 5 5 4 2 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.6 KFX91488.1 - 0.00041 20.4 0.3 1.9 8.5 0.0 3.4 3 0 0 3 3 3 2 AAA domain NACHT PF05729.12 KFX91488.1 - 0.00093 19.2 0.3 0.35 10.8 0.0 2.6 2 0 0 2 2 2 1 NACHT domain AAA_15 PF13175.6 KFX91488.1 - 0.0013 18.5 15.3 0.27 10.9 0.0 5.0 4 1 1 5 5 5 2 AAA ATPase domain RNA_helicase PF00910.22 KFX91488.1 - 0.0023 18.3 0.0 3.9 7.9 0.0 2.9 2 0 0 2 2 2 1 RNA helicase Dynamin_N PF00350.23 KFX91488.1 - 0.0057 16.7 4.9 9.2 6.3 0.0 4.1 4 0 0 4 4 4 0 Dynamin family MobB PF03205.14 KFX91488.1 - 0.0078 16.1 0.2 0.35 10.8 0.0 2.7 3 0 0 3 3 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_28 PF13521.6 KFX91488.1 - 0.0099 16.1 8.8 0.25 11.6 0.0 3.8 4 0 0 4 4 4 1 AAA domain NTPase_1 PF03266.15 KFX91488.1 - 0.012 15.5 0.0 1.5 8.7 0.0 2.8 2 0 0 2 2 2 0 NTPase MeaB PF03308.16 KFX91488.1 - 0.022 13.8 2.8 2.6 6.9 0.0 3.0 3 1 1 4 4 3 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_7 PF12775.7 KFX91488.1 - 0.031 13.8 0.0 6.4 6.2 0.0 2.5 2 0 0 2 2 2 0 P-loop containing dynein motor region Zeta_toxin PF06414.12 KFX91488.1 - 0.039 13.2 1.9 3.4 6.9 0.1 2.7 3 0 0 3 3 2 0 Zeta toxin SRP54 PF00448.22 KFX91488.1 - 0.045 13.4 0.3 6 6.4 0.3 2.7 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain TsaE PF02367.17 KFX91488.1 - 0.045 13.7 0.0 14 5.7 0.0 2.7 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_5 PF07728.14 KFX91488.1 - 0.051 13.6 0.6 7.4 6.6 0.0 3.0 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) ATP-synt_ab PF00006.25 KFX91488.1 - 0.061 13.0 0.0 1.2 8.8 0.0 2.3 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain Roc PF08477.13 KFX91488.1 - 0.062 13.5 0.7 12 6.1 0.0 2.9 3 0 0 3 3 2 0 Ras of Complex, Roc, domain of DAPkinase cobW PF02492.19 KFX91488.1 - 0.066 12.8 3.8 1.4 8.5 0.6 2.9 2 1 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_25 PF13481.6 KFX91488.1 - 0.079 12.5 0.1 12 5.4 0.0 2.9 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.22 KFX91488.1 - 0.083 12.1 0.0 16 4.6 0.0 2.5 2 0 0 2 2 2 0 NB-ARC domain Rad17 PF03215.15 KFX91488.1 - 0.12 12.3 0.4 3.4 7.5 0.0 2.9 3 0 0 3 3 3 0 Rad17 P-loop domain DUF87 PF01935.17 KFX91488.1 - 0.23 11.5 10.0 1.6 8.8 0.0 4.5 5 1 1 6 6 5 0 Helicase HerA, central domain AAA_17 PF13207.6 KFX91488.1 - 0.35 11.3 5.0 27 5.2 0.3 3.7 3 0 0 3 3 3 0 AAA domain AAA_27 PF13514.6 KFX91488.1 - 0.37 10.3 8.3 5.2 6.6 0.0 4.2 6 0 0 6 6 5 0 AAA domain ATPase_2 PF01637.18 KFX91488.1 - 7.8 6.3 7.1 28 4.5 0.0 3.6 4 0 0 4 4 4 0 ATPase domain predominantly from Archaea Tubulin PF00091.25 KFX91489.1 - 1.1e-68 231.4 0.0 2.7e-68 230.1 0.0 1.6 2 0 0 2 2 2 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 KFX91489.1 - 3.8e-43 146.6 0.1 6e-43 146.0 0.1 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.9 KFX91489.1 - 4.7e-05 23.7 0.1 0.00013 22.2 0.0 1.8 2 0 0 2 2 2 1 Misato Segment II tubulin-like domain Tubulin_2 PF13809.6 KFX91489.1 - 0.0023 17.2 0.0 0.025 13.8 0.0 2.1 2 0 0 2 2 2 1 Tubulin like Tubulin_3 PF14881.6 KFX91489.1 - 0.0033 17.1 0.0 0.0057 16.4 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain GN3L_Grn1 PF08701.11 KFX91490.1 - 2.8e-22 78.6 14.4 2.8e-22 78.6 14.4 2.2 2 0 0 2 2 2 1 GNL3L/Grn1 putative GTPase MMR_HSR1 PF01926.23 KFX91490.1 - 8.7e-18 64.5 0.2 8.6e-13 48.4 0.0 2.4 2 0 0 2 2 2 2 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KFX91490.1 - 3.4e-07 30.3 0.3 6.2e-06 26.2 0.3 2.2 1 1 0 1 1 1 1 RsgA GTPase FeoB_N PF02421.18 KFX91490.1 - 2e-06 27.4 0.1 4e-05 23.2 0.0 2.2 2 0 0 2 2 2 1 Ferrous iron transport protein B Dynamin_N PF00350.23 KFX91490.1 - 3.5e-05 23.9 7.7 0.073 13.1 2.4 3.4 2 2 0 3 3 3 2 Dynamin family GTP_EFTU PF00009.27 KFX91490.1 - 8.6e-05 22.2 0.0 0.021 14.4 0.0 2.7 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain MeaB PF03308.16 KFX91490.1 - 0.014 14.4 0.1 0.034 13.1 0.1 1.6 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB RRN3 PF05327.11 KFX91490.1 - 0.033 12.7 3.6 0.045 12.3 3.6 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Arf PF00025.21 KFX91490.1 - 0.034 13.6 0.0 0.36 10.3 0.0 2.2 2 0 0 2 2 2 0 ADP-ribosylation factor family cobW PF02492.19 KFX91490.1 - 0.082 12.5 0.1 0.57 9.7 0.0 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_18 PF13238.6 KFX91490.1 - 0.24 12.0 0.0 0.24 12.0 0.0 2.3 2 1 0 2 2 2 0 AAA domain BUD22 PF09073.10 KFX91490.1 - 4.8 6.4 22.4 7.5 5.8 22.4 1.2 1 0 0 1 1 1 0 BUD22 HAD_2 PF13419.6 KFX91491.1 - 3.6e-18 66.3 0.0 6.3e-18 65.5 0.0 1.4 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KFX91491.1 - 6.4e-09 36.4 0.0 0.00012 22.4 0.0 2.3 1 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KFX91491.1 - 1.6e-06 28.1 0.1 2.6e-06 27.4 0.1 1.3 1 0 0 1 1 1 1 HAD-hyrolase-like ADH_zinc_N PF00107.26 KFX91491.1 - 0.0058 16.6 1.4 0.017 15.1 0.5 2.0 2 1 0 2 2 2 1 Zinc-binding dehydrogenase HAD PF12710.7 KFX91491.1 - 0.01 16.2 0.0 0.02 15.3 0.0 1.4 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase SLD3 PF08639.10 KFX91492.1 - 1.8e-139 466.0 2.9 1.8e-139 466.0 2.9 1.8 2 1 1 3 3 3 1 DNA replication regulator SLD3 Cu-oxidase_3 PF07732.15 KFX91494.1 - 8.3e-48 161.3 0.6 2.4e-47 159.8 0.2 1.9 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase PF00394.22 KFX91494.1 - 1.3e-38 132.7 0.5 3.6e-38 131.2 0.1 1.9 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 KFX91494.1 - 0.00025 20.8 0.5 0.004 16.9 0.4 2.5 1 1 0 1 1 1 1 Multicopper oxidase DUF5620 PF18522.1 KFX91494.1 - 0.029 14.7 0.2 0.053 13.9 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5620) Phosphoesterase PF04185.14 KFX91495.1 - 1.2e-34 120.0 4.0 3.1e-34 118.7 4.0 1.6 1 1 0 1 1 1 1 Phosphoesterase family HIF-1a_CTAD PF08778.10 KFX91495.1 - 0.097 12.3 0.0 0.18 11.4 0.0 1.4 1 0 0 1 1 1 0 HIF-1 alpha C terminal transactivation domain FCH PF00611.23 KFX91502.1 - 1.7e-10 41.0 0.4 5.4e-10 39.4 0.1 2.0 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain GDP_Man_Dehyd PF16363.5 KFX91512.1 - 1.5e-70 238.2 0.0 1.8e-70 238.0 0.0 1.0 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 KFX91512.1 - 5.3e-58 196.3 0.0 7e-58 195.9 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 KFX91512.1 - 4.3e-23 81.9 0.0 4.4e-22 78.6 0.0 1.9 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.19 KFX91512.1 - 1.5e-19 70.1 0.0 2.4e-19 69.4 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 KFX91512.1 - 2.6e-19 69.4 0.0 3.6e-18 65.7 0.0 2.2 1 1 0 1 1 1 1 Male sterility protein RmlD_sub_bind PF04321.17 KFX91512.1 - 1e-17 64.2 0.0 1.3e-17 63.9 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_10 PF13460.6 KFX91512.1 - 1.5e-06 28.3 0.0 2.6e-06 27.4 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding adh_short PF00106.25 KFX91512.1 - 0.034 13.6 0.0 1.9 7.9 0.1 2.3 2 0 0 2 2 2 0 short chain dehydrogenase Glyco_hydro_2 PF00703.21 KFX91514.1 - 7.2e-09 36.3 0.0 2.3e-08 34.7 0.0 1.9 2 0 0 2 2 2 1 Glycosyl hydrolases family 2 Glyco_hydro_2_C PF02836.17 KFX91514.1 - 0.0051 16.0 0.2 0.025 13.7 0.2 2.0 1 1 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Glyco_hydro_2_N PF02837.18 KFX91514.1 - 0.012 15.6 0.0 0.024 14.5 0.0 1.5 1 0 0 1 1 1 0 Glycosyl hydrolases family 2, sugar binding domain Cytotoxic PF09000.10 KFX91514.1 - 0.083 13.2 0.3 0.2 12.0 0.3 1.6 1 0 0 1 1 1 0 Cytotoxic Mannosidase_ig PF17786.1 KFX91515.1 - 9.9e-15 54.9 0.3 2e-14 53.9 0.1 1.5 2 0 0 2 2 2 1 Mannosidase Ig/CBM-like domain Ig_mannosidase PF17753.1 KFX91515.1 - 1.4e-05 24.8 0.0 2.7e-05 23.8 0.0 1.5 1 0 0 1 1 1 1 Ig-fold domain Lung_7-TM_R PF06814.13 KFX91539.1 - 2.3e-72 243.8 15.5 2.8e-72 243.5 15.5 1.1 1 0 0 1 1 1 1 Lung seven transmembrane receptor CTU2 PF10288.9 KFX91540.1 - 3.1e-14 53.1 1.8 2.6e-13 50.2 0.1 2.8 2 1 0 2 2 2 1 Cytoplasmic tRNA 2-thiolation protein 2 RNA_pol_Rpc4 PF05132.14 KFX91541.1 - 9.8e-28 97.5 2.3 1.9e-27 96.5 0.0 2.2 2 0 0 2 2 2 1 RNA polymerase III RPC4 Cnd2 PF05786.14 KFX91544.1 - 0 1076.5 1.4 0 1076.3 1.4 1.0 1 0 0 1 1 1 1 Condensin complex subunit 2 CNDH2_N PF06278.11 KFX91544.1 - 0.013 15.8 0.0 0.035 14.3 0.0 1.7 1 0 0 1 1 1 0 Condensin II complex subunit CAP-H2 or CNDH2, N-terminal Na_Ca_ex PF01699.24 KFX91545.1 - 1.9e-51 174.0 44.5 1e-26 93.7 20.8 2.6 3 0 0 3 3 3 2 Sodium/calcium exchanger protein HemY_N PF07219.13 KFX91545.1 - 2.1 8.6 4.3 40 4.5 1.5 3.0 2 0 0 2 2 2 0 HemY protein N-terminus Vpu PF00558.19 KFX91545.1 - 5.6 6.8 4.8 11 5.9 0.0 3.1 3 0 0 3 3 3 0 Vpu protein PDR_CDR PF06422.12 KFX91545.1 - 7.9 6.5 5.4 7.3 6.6 0.5 3.3 4 1 0 4 4 4 0 CDR ABC transporter IncE PF17627.2 KFX91545.1 - 8.9 6.3 10.9 13 5.8 3.7 2.5 2 0 0 2 2 2 0 Inclusion membrane protein E MPC PF03650.13 KFX91546.1 - 1.9e-35 121.3 0.0 2.4e-35 121.0 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial pyruvate carriers LSM PF01423.22 KFX91547.1 - 1.7e-18 66.1 0.0 2.2e-18 65.7 0.0 1.1 1 0 0 1 1 1 1 LSM domain Ribosomal_L5_C PF00673.21 KFX91548.1 - 1.7e-21 76.2 0.0 2.9e-21 75.5 0.0 1.4 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.19 KFX91548.1 - 2.3e-19 69.5 0.0 4.8e-19 68.4 0.0 1.6 1 0 0 1 1 1 1 Ribosomal protein L5 PYC_OADA PF02436.18 KFX91550.1 - 2.3e-66 223.4 0.0 3.7e-66 222.7 0.0 1.4 1 0 0 1 1 1 1 Conserved carboxylase domain HMGL-like PF00682.19 KFX91550.1 - 2e-26 93.2 0.0 3.5e-26 92.3 0.0 1.4 1 0 0 1 1 1 1 HMGL-like Biotin_lipoyl PF00364.22 KFX91550.1 - 3.5e-17 62.0 5.5 8e-17 60.8 4.5 2.1 2 0 0 2 2 2 1 Biotin-requiring enzyme Biotin_carb_C PF02785.19 KFX91550.1 - 8.8e-13 48.3 0.0 4.1e-12 46.1 0.0 2.1 2 0 0 2 2 2 1 Biotin carboxylase C-terminal domain Biotin_lipoyl_2 PF13533.6 KFX91550.1 - 1e-07 31.7 2.9 2.6e-07 30.4 0.4 2.4 1 1 1 2 2 2 1 Biotin-lipoyl like HlyD_D23 PF16576.5 KFX91550.1 - 0.0042 16.3 0.8 0.048 12.9 0.1 2.2 1 1 1 2 2 2 1 Barrel-sandwich domain of CusB or HlyD membrane-fusion DUF2118 PF09891.9 KFX91550.1 - 0.0087 16.0 0.7 0.018 15.0 0.7 1.5 1 0 0 1 1 1 1 Uncharacterized protein conserved in archaea (DUF2118) QRPTase_N PF02749.16 KFX91550.1 - 0.037 14.1 1.3 0.24 11.5 0.2 2.7 2 1 1 3 3 3 0 Quinolinate phosphoribosyl transferase, N-terminal domain HlyD_3 PF13437.6 KFX91550.1 - 0.054 14.2 1.5 0.3 11.8 0.9 2.4 2 1 1 3 3 3 0 HlyD family secretion protein GCV_H PF01597.19 KFX91550.1 - 0.23 11.4 1.8 0.82 9.6 0.7 2.3 2 0 0 2 2 2 0 Glycine cleavage H-protein CPSase_L_D2 PF02786.17 KFX91551.1 - 1.1e-82 276.7 0.1 1.8e-82 276.0 0.1 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_N PF00289.22 KFX91551.1 - 2e-36 124.9 0.0 3.7e-36 124.0 0.0 1.5 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Dala_Dala_lig_C PF07478.13 KFX91551.1 - 3.8e-11 42.9 0.0 7.6e-11 41.9 0.0 1.4 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.22 KFX91551.1 - 2.1e-08 33.9 0.1 3.5e-08 33.2 0.1 1.3 1 0 0 1 1 1 1 ATP-grasp domain Biotin_carb_C PF02785.19 KFX91551.1 - 4.1e-08 33.3 0.0 8.1e-08 32.3 0.0 1.5 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain ATP-grasp_3 PF02655.14 KFX91551.1 - 1.2e-06 28.7 0.2 7.4e-06 26.1 0.0 2.1 2 0 0 2 2 2 1 ATP-grasp domain RimK PF08443.11 KFX91551.1 - 1.6e-06 27.9 0.0 5.6e-06 26.1 0.0 1.8 1 1 0 1 1 1 1 RimK-like ATP-grasp domain ATPgrasp_ST PF14397.6 KFX91551.1 - 0.00033 20.0 0.0 0.00081 18.7 0.0 1.6 2 0 0 2 2 2 1 Sugar-transfer associated ATP-grasp ATP-grasp_4 PF13535.6 KFX91551.1 - 0.00072 19.2 0.0 0.0015 18.1 0.0 1.6 1 0 0 1 1 1 1 ATP-grasp domain ATPgrasp_YheCD PF14398.6 KFX91551.1 - 0.00084 18.7 0.0 0.28 10.4 0.0 2.4 2 0 0 2 2 2 2 YheC/D like ATP-grasp GARS_A PF01071.19 KFX91551.1 - 0.0037 17.0 0.0 0.0096 15.7 0.0 1.7 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain KH_4 PF13083.6 KFX91551.1 - 0.073 13.0 0.0 0.86 9.5 0.0 2.4 2 0 0 2 2 2 0 KH domain ATPgrasp_Ter PF15632.6 KFX91551.1 - 0.097 12.4 0.6 0.21 11.3 0.1 1.8 2 0 0 2 2 2 0 ATP-grasp in the biosynthetic pathway with Ter operon Spond_N PF06468.13 KFX91551.1 - 0.15 12.2 0.0 0.29 11.2 0.0 1.4 1 0 0 1 1 1 0 Spondin_N Clathrin PF00637.20 KFX91552.1 - 7.1e-206 674.4 40.8 1.3e-33 115.8 3.0 7.6 7 1 1 8 8 8 7 Region in Clathrin and VPS Clathrin_propel PF01394.20 KFX91552.1 - 2.6e-34 115.9 0.1 2.4e-07 30.7 0.1 6.7 6 0 0 6 6 6 6 Clathrin propeller repeat Clathrin_H_link PF13838.6 KFX91552.1 - 1.6e-33 114.4 2.3 4.1e-33 113.1 0.3 2.9 2 1 1 3 3 3 1 Clathrin-H-link TPR_7 PF13176.6 KFX91552.1 - 8e-05 22.4 3.3 40 4.6 0.0 6.9 6 0 0 6 6 6 0 Tetratricopeptide repeat Clathrin-link PF09268.10 KFX91552.1 - 0.00044 19.5 0.5 0.0015 17.8 0.0 2.2 2 0 0 2 2 2 1 Clathrin, heavy-chain linker TPR_8 PF13181.6 KFX91552.1 - 0.00046 20.2 3.4 1.9 8.9 0.0 5.8 5 0 0 5 5 5 1 Tetratricopeptide repeat Vps39_1 PF10366.9 KFX91552.1 - 0.0058 16.9 13.0 14 6.1 0.0 7.1 5 2 3 8 8 8 1 Vacuolar sorting protein 39 domain 1 Cytidylate_kin2 PF13189.6 KFX91552.1 - 0.015 15.5 0.0 6.2 6.9 0.0 3.0 2 0 0 2 2 2 0 Cytidylate kinase-like family TPR_12 PF13424.6 KFX91552.1 - 0.019 15.2 0.8 83 3.6 0.0 5.0 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_14 PF13428.6 KFX91552.1 - 0.023 15.5 13.9 0.94 10.5 0.1 7.4 9 0 0 9 9 7 0 Tetratricopeptide repeat TPR_1 PF00515.28 KFX91552.1 - 0.039 13.8 1.9 14 5.7 0.0 5.1 5 0 0 5 5 5 0 Tetratricopeptide repeat Coatomer_WDAD PF04053.14 KFX91552.1 - 1.4 7.9 11.4 0.76 8.7 0.4 4.0 5 0 0 5 5 5 0 Coatomer WD associated region TPR_2 PF07719.17 KFX91552.1 - 6.2 7.2 11.3 36 4.8 0.0 6.6 7 0 0 7 7 6 0 Tetratricopeptide repeat ACC_epsilon PF13822.6 KFX91553.1 - 2.5 8.8 7.6 4.7 8.0 7.6 1.7 1 1 0 1 1 1 0 Acyl-CoA carboxylase epsilon subunit AICARFT_IMPCHas PF01808.18 KFX91554.1 - 1.4e-91 307.0 0.0 2e-91 306.5 0.0 1.2 1 0 0 1 1 1 1 AICARFT/IMPCHase bienzyme MGS PF02142.22 KFX91554.1 - 6e-23 80.8 0.0 1.2e-22 79.8 0.0 1.6 1 0 0 1 1 1 1 MGS-like domain WSC PF01822.19 KFX91560.1 - 8.6e-44 147.6 38.8 2.2e-15 56.6 8.3 3.8 3 0 0 3 3 3 3 WSC domain Glyco_hydro_18 PF00704.28 KFX91560.1 - 7.8e-17 62.0 0.6 1.9e-16 60.7 0.6 1.6 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 LysM PF01476.20 KFX91560.1 - 8.3e-06 25.8 0.1 1.6e-05 24.9 0.1 1.5 1 0 0 1 1 1 1 LysM domain Sporozoite_P67 PF05642.11 KFX91560.1 - 2.9 5.9 6.0 1.7 6.6 3.2 1.8 2 0 0 2 2 2 0 Sporozoite P67 surface antigen UDPGP PF01704.18 KFX91562.1 - 1.6e-190 633.1 0.0 1.9e-190 632.9 0.0 1.1 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase Neurensin PF14927.6 KFX91562.1 - 0.017 14.8 0.4 0.26 11.0 0.1 2.2 2 0 0 2 2 2 0 Neurensin Innate_immun PF12782.7 KFX91562.1 - 0.03 13.8 0.1 0.051 13.1 0.1 1.3 1 0 0 1 1 1 0 Invertebrate innate immunity transcript family DUF2721 PF11026.8 KFX91562.1 - 0.13 12.2 0.0 0.43 10.5 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2721) DUF4301 PF14134.6 KFX91562.1 - 5.8 5.6 6.3 3.5 6.3 0.1 3.0 2 1 1 3 3 3 0 Domain of unknown function (DUF4301) F-box-like PF12937.7 KFX91564.1 - 1.5e-05 24.8 0.5 3.2e-05 23.7 0.5 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KFX91564.1 - 0.00028 20.7 0.1 0.00061 19.6 0.1 1.5 1 0 0 1 1 1 1 F-box domain F-box-like_2 PF13013.6 KFX91564.1 - 0.078 13.0 0.1 0.17 11.8 0.1 1.5 1 0 0 1 1 1 0 F-box-like domain ANAPC4_WD40 PF12894.7 KFX91564.1 - 0.11 12.8 0.0 0.52 10.7 0.0 2.0 1 1 1 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain DUF908 PF06012.12 KFX91565.1 - 0.1 12.0 5.7 0.18 11.2 5.7 1.4 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) CBM_1 PF00734.18 KFX91566.1 - 5e-08 32.8 6.6 5e-08 32.8 6.6 3.1 4 0 0 4 4 4 2 Fungal cellulose binding domain MAR_sialic_bdg PF10564.9 KFX91566.1 - 2.9 8.0 6.7 5.1 7.2 0.6 2.7 2 1 1 3 3 3 0 Sialic-acid binding micronemal adhesive repeat UPF1_Zn_bind PF09416.10 KFX91568.1 - 2.6e-71 238.5 0.8 5e-71 237.6 0.4 1.7 2 0 0 2 2 2 1 RNA helicase (UPF2 interacting domain) AAA_12 PF13087.6 KFX91568.1 - 1.5e-59 201.0 0.0 2.7e-59 200.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 KFX91568.1 - 8.7e-55 186.3 2.6 1.6e-31 110.1 0.2 2.3 1 1 1 2 2 2 2 AAA domain DUF5599 PF18141.1 KFX91568.1 - 8.7e-32 109.2 0.0 1.7e-31 108.3 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF5599) AAA_30 PF13604.6 KFX91568.1 - 1.5e-13 50.9 0.1 1.3e-12 47.8 0.1 2.3 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KFX91568.1 - 8.2e-11 42.4 0.0 5.3e-10 39.8 0.0 2.4 2 1 0 2 2 2 1 AAA domain ResIII PF04851.15 KFX91568.1 - 1.9e-05 24.8 0.0 3.4e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Viral_helicase1 PF01443.18 KFX91568.1 - 0.00011 22.1 0.2 0.35 10.6 0.0 2.8 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase DUF2075 PF09848.9 KFX91568.1 - 0.00072 18.9 0.0 0.022 14.0 0.0 2.4 3 0 0 3 3 3 1 Uncharacterized conserved protein (DUF2075) Helicase_RecD PF05127.14 KFX91568.1 - 0.0022 17.9 0.0 0.0042 17.0 0.0 1.5 1 0 0 1 1 1 1 Helicase UvrD-helicase PF00580.21 KFX91568.1 - 0.0038 16.8 0.0 0.025 14.1 0.0 2.0 1 1 0 2 2 2 1 UvrD/REP helicase N-terminal domain PIF1 PF05970.14 KFX91568.1 - 0.0045 16.2 0.0 0.43 9.7 0.0 2.2 2 0 0 2 2 2 1 PIF1-like helicase DEAD PF00270.29 KFX91568.1 - 0.005 16.6 0.0 0.0099 15.7 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 KFX91568.1 - 0.025 14.9 0.1 0.075 13.3 0.1 1.7 1 0 0 1 1 1 0 AAA domain AAA_10 PF12846.7 KFX91568.1 - 0.026 13.5 0.0 0.039 12.9 0.0 1.2 1 0 0 1 1 1 0 AAA-like domain ATPase PF06745.13 KFX91568.1 - 0.11 11.9 0.0 0.19 11.0 0.0 1.3 1 0 0 1 1 1 0 KaiC Ribosomal_S13_N PF08069.12 KFX91568.1 - 0.17 11.9 0.0 0.45 10.6 0.0 1.7 1 0 0 1 1 1 0 Ribosomal S13/S15 N-terminal domain SRP54 PF00448.22 KFX91568.1 - 0.17 11.5 0.0 0.41 10.3 0.0 1.6 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain Brix PF04427.18 KFX91569.1 - 1.6e-31 110.0 0.2 2.7e-31 109.2 0.2 1.4 1 0 0 1 1 1 1 Brix domain Syntaxin PF00804.25 KFX91569.1 - 2.7e-20 72.9 4.6 4.8e-20 72.1 4.6 1.4 1 0 0 1 1 1 1 Syntaxin SNARE PF05739.19 KFX91569.1 - 8.5e-13 48.1 0.0 2.2e-12 46.8 0.0 1.8 1 0 0 1 1 1 1 SNARE domain Syntaxin_2 PF14523.6 KFX91569.1 - 0.0002 21.7 4.8 0.0002 21.7 1.7 2.4 2 0 0 2 2 2 1 Syntaxin-like protein Bacillus_HBL PF05791.11 KFX91569.1 - 0.046 13.5 0.9 0.12 12.2 0.9 1.6 1 0 0 1 1 1 0 Bacillus haemolytic enterotoxin (HBL) RPW8 PF05659.11 KFX91569.1 - 0.053 13.2 0.2 0.27 10.9 0.0 2.1 2 0 0 2 2 2 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 Phage_HK97_TLTM PF06120.11 KFX91569.1 - 0.087 12.0 3.5 0.17 11.1 3.5 1.5 1 0 0 1 1 1 0 Tail length tape measure protein Bac_export_3 PF01313.19 KFX91569.1 - 0.11 12.5 0.2 0.18 11.7 0.2 1.3 1 0 0 1 1 1 0 Bacterial export proteins, family 3 Tad PF13400.6 KFX91569.1 - 0.11 12.9 0.4 0.11 12.9 0.4 3.0 3 0 0 3 3 3 0 Putative Flp pilus-assembly TadE/G-like SNAD1 PF18744.1 KFX91569.1 - 0.16 11.8 0.1 0.27 11.1 0.1 1.3 1 0 0 1 1 1 0 Secreted Novel AID/APOBEC-like Deaminase 1 OmpH PF03938.14 KFX91569.1 - 1.2 9.5 9.9 0.38 11.1 4.1 2.5 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) Mod_r PF07200.13 KFX91569.1 - 4.4 7.4 10.1 2.6 8.2 3.4 2.5 1 1 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein DUF2203 PF09969.9 KFX91569.1 - 6.2 7.6 6.1 39 5.0 0.1 2.8 2 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) COPIIcoated_ERV PF07970.12 KFX91570.1 - 3.7e-36 125.1 0.6 5.2e-36 124.6 0.6 1.2 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.6 KFX91570.1 - 5.6e-23 81.1 0.0 1e-22 80.2 0.0 1.5 1 0 0 1 1 1 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) Peptidase_C97 PF05903.14 KFX91571.1 - 2e-05 24.4 0.1 3.6e-05 23.6 0.1 1.4 1 0 0 1 1 1 1 PPPDE putative peptidase domain LRAT PF04970.13 KFX91571.1 - 0.043 14.1 1.1 0.29 11.4 1.1 2.3 1 1 0 1 1 1 0 Lecithin retinol acyltransferase DUF4105 PF13387.6 KFX91571.1 - 0.048 13.3 0.1 0.079 12.6 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4105) DUF778 PF05608.12 KFX91571.1 - 0.09 13.1 3.5 0.19 12.1 0.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF778) AhpC-TSA_2 PF13911.6 KFX91572.1 - 5.3e-19 68.4 0.0 2.1e-18 66.5 0.0 1.8 2 0 0 2 2 2 1 AhpC/TSA antioxidant enzyme AhpC-TSA PF00578.21 KFX91572.1 - 0.0014 18.6 0.0 0.0028 17.6 0.0 1.5 1 1 0 1 1 1 1 AhpC/TSA family HET PF06985.11 KFX91575.1 - 8.8e-27 94.2 0.0 2.4e-26 92.8 0.0 1.8 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) WW PF00397.26 KFX91582.1 - 1.3e-10 41.1 0.2 2.9e-10 40.1 0.2 1.6 1 0 0 1 1 1 1 WW domain zf-C2H2 PF00096.26 KFX91583.1 - 0.016 15.6 3.5 0.046 14.2 3.5 1.8 1 0 0 1 1 1 0 Zinc finger, C2H2 type zf-BED PF02892.15 KFX91583.1 - 0.056 13.5 2.0 0.13 12.3 2.0 1.6 1 0 0 1 1 1 0 BED zinc finger zf-H2C2_2 PF13465.6 KFX91583.1 - 0.19 12.3 2.7 5.3 7.7 0.5 2.7 2 0 0 2 2 2 0 Zinc-finger double domain MGC-24 PF05283.11 KFX91583.1 - 0.46 10.9 5.4 0.17 12.4 0.3 2.2 2 0 0 2 2 2 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin Pex24p PF06398.11 KFX91601.1 - 1.1e-24 87.2 3.1 1.2e-24 87.0 3.1 1.1 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin PARP PF00644.20 KFX91603.1 - 1.9e-12 47.2 0.0 2.3e-09 37.1 0.0 2.4 1 1 1 2 2 2 2 Poly(ADP-ribose) polymerase catalytic domain cobW PF02492.19 KFX91605.1 - 3.3e-41 140.8 0.0 4.8e-41 140.3 0.0 1.2 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain MobB PF03205.14 KFX91605.1 - 0.00022 21.1 0.0 0.00047 20.1 0.0 1.7 1 1 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_22 PF13401.6 KFX91605.1 - 0.018 15.3 0.0 0.44 10.8 0.0 2.2 2 0 0 2 2 2 0 AAA domain DUF463 PF04317.12 KFX91605.1 - 0.021 13.8 0.0 0.032 13.2 0.0 1.2 1 0 0 1 1 1 0 YcjX-like family, DUF463 BESS PF02944.20 KFX91605.1 - 0.023 14.5 0.5 0.038 13.8 0.5 1.3 1 0 0 1 1 1 0 BESS motif AAA_29 PF13555.6 KFX91605.1 - 0.023 14.4 0.4 0.3 10.8 0.1 2.5 2 0 0 2 2 2 0 P-loop containing region of AAA domain Viral_helicase1 PF01443.18 KFX91605.1 - 0.08 12.7 0.0 0.16 11.7 0.0 1.5 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase DUF3597 PF12200.8 KFX91606.1 - 0.94 10.0 3.5 2.1 8.9 1.4 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3597) TPP_enzyme_N PF02776.18 KFX91609.1 - 2e-53 180.5 0.0 4e-53 179.5 0.0 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.22 KFX91609.1 - 1.8e-39 134.6 0.2 1.8e-39 134.6 0.2 2.4 3 0 0 3 3 3 1 Thiamine pyrophosphate enzyme, central domain POR_N PF01855.19 KFX91609.1 - 0.04 13.7 0.0 0.079 12.7 0.0 1.4 1 0 0 1 1 1 0 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg zf-C2H2 PF00096.26 KFX91610.1 - 0.00015 22.0 23.2 0.013 15.9 0.3 4.7 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFX91610.1 - 0.028 15.2 0.4 0.028 15.2 0.4 5.1 6 0 0 6 6 6 0 C2H2-type zinc finger zf-C2HC_2 PF13913.6 KFX91610.1 - 0.06 13.3 1.0 0.14 12.1 1.0 1.6 1 0 0 1 1 1 0 zinc-finger of a C2HC-type SUIM_assoc PF16619.5 KFX91610.1 - 9.6 6.4 13.0 4 7.6 1.4 3.2 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 F-box-like PF12937.7 KFX91611.1 - 3.7e-05 23.5 0.2 0.00014 21.7 0.2 2.0 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KFX91611.1 - 0.00026 20.8 0.1 0.00053 19.8 0.1 1.5 1 0 0 1 1 1 1 F-box domain CDC24_OB2 PF17245.2 KFX91611.1 - 0.017 15.7 0.1 0.028 15.0 0.1 1.4 1 0 0 1 1 1 0 Cell division control protein 24, OB domain 2 MFS_1 PF07690.16 KFX91615.1 - 1.8e-38 132.4 45.8 3.4e-38 131.5 41.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KFX91615.1 - 2e-08 33.6 8.0 2e-08 33.6 8.0 1.9 2 1 0 2 2 2 1 Sugar (and other) transporter dTDP_sugar_isom PF00908.17 KFX91615.1 - 0.18 11.5 0.0 0.47 10.1 0.0 1.6 2 0 0 2 2 2 0 dTDP-4-dehydrorhamnose 3,5-epimerase Pectinesterase PF01095.19 KFX91617.1 - 2.5e-37 128.2 7.6 3.5e-37 127.7 7.6 1.1 1 0 0 1 1 1 1 Pectinesterase Ribosomal_L28e PF01778.17 KFX91617.1 - 0.026 15.3 1.2 0.05 14.4 1.2 1.4 1 0 0 1 1 1 0 Ribosomal L28e protein family DUF2430 PF10353.9 KFX91617.1 - 0.075 13.4 0.0 6.2 7.3 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2430) Pkinase PF00069.25 KFX91619.1 - 1.2e-61 208.4 0.0 1.6e-61 208.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFX91619.1 - 1.1e-32 113.4 0.0 1.6e-32 112.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KFX91619.1 - 0.0018 17.7 0.0 0.0029 17.0 0.0 1.3 1 0 0 1 1 1 1 Kinase-like DUF1677 PF07911.13 KFX91619.1 - 0.18 12.2 0.1 0.65 10.4 0.2 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1677) UBA PF00627.31 KFX91627.1 - 1.6e-14 53.4 0.5 2.4e-14 52.8 0.5 1.3 1 0 0 1 1 1 1 UBA/TS-N domain Goodbye PF17109.5 KFX91628.1 - 1.1e-36 126.0 0.0 2.7e-36 124.7 0.0 1.8 1 0 0 1 1 1 1 fungal STAND N-terminal Goodbye domain NACHT PF05729.12 KFX91628.1 - 1.3e-08 34.9 0.0 3.4e-08 33.6 0.0 1.7 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 KFX91628.1 - 1.7e-06 28.5 0.2 1.2e-05 25.8 0.0 2.5 3 0 0 3 3 3 1 AAA ATPase domain AAA_22 PF13401.6 KFX91628.1 - 7.2e-05 23.1 0.0 0.00026 21.3 0.0 2.0 1 0 0 1 1 1 1 AAA domain TPR_12 PF13424.6 KFX91628.1 - 0.007 16.6 0.5 0.56 10.5 0.0 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat RNA_helicase PF00910.22 KFX91628.1 - 0.008 16.6 0.0 0.018 15.5 0.0 1.6 1 0 0 1 1 1 1 RNA helicase AAA_5 PF07728.14 KFX91628.1 - 0.019 14.9 0.1 1.3 9.1 0.0 2.7 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA PF00004.29 KFX91628.1 - 0.029 14.8 0.0 0.14 12.6 0.0 2.1 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) FYVE PF01363.21 KFX91628.1 - 0.059 13.5 2.2 0.13 12.5 2.2 1.5 1 0 0 1 1 1 0 FYVE zinc finger AAA_17 PF13207.6 KFX91628.1 - 0.3 11.5 0.9 5.8 7.3 0.1 3.4 4 0 0 4 4 4 0 AAA domain GMC_oxred_N PF00732.19 KFX91629.1 - 2.3e-50 171.7 0.0 3e-50 171.3 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KFX91629.1 - 1.2e-32 113.4 0.0 1.9e-32 112.8 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 KFX91629.1 - 1.6e-05 24.1 1.2 0.072 12.2 1.2 2.1 2 0 0 2 2 2 2 FAD binding domain Thi4 PF01946.17 KFX91629.1 - 0.00025 20.4 0.1 0.00063 19.1 0.1 1.6 1 0 0 1 1 1 1 Thi4 family Lycopene_cycl PF05834.12 KFX91629.1 - 0.0023 17.0 0.0 0.0054 15.8 0.0 1.6 2 0 0 2 2 2 1 Lycopene cyclase protein DAO PF01266.24 KFX91629.1 - 0.015 14.9 1.8 0.081 12.5 2.0 2.2 2 1 0 2 2 2 0 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KFX91629.1 - 0.019 14.2 0.0 0.069 12.4 0.0 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KFX91629.1 - 0.044 14.0 0.4 0.12 12.6 0.4 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 KFX91629.1 - 0.08 12.2 0.0 11 5.1 0.0 2.5 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Catalase PF00199.19 KFX91631.1 - 7.4e-176 584.9 1.4 8.8e-176 584.7 1.4 1.0 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.12 KFX91631.1 - 7.2e-13 48.5 0.0 1.9e-12 47.2 0.0 1.8 1 0 0 1 1 1 1 Catalase-related immune-responsive CAP_N PF01213.19 KFX91632.1 - 0.05 13.1 4.0 0.055 12.9 4.0 1.0 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal SBP_bac_5 PF00496.22 KFX91632.1 - 0.068 12.1 0.7 0.072 12.0 0.7 1.0 1 0 0 1 1 1 0 Bacterial extracellular solute-binding proteins, family 5 Middle SKG6 PF08693.10 KFX91633.1 - 0.0029 17.0 0.6 0.0062 15.9 0.6 1.6 1 0 0 1 1 1 1 Transmembrane alpha-helix domain CD34_antigen PF06365.12 KFX91633.1 - 0.081 12.5 0.0 0.13 11.9 0.0 1.2 1 0 0 1 1 1 0 CD34/Podocalyxin family TMEM132D_C PF15706.5 KFX91633.1 - 0.1 12.4 0.0 0.19 11.5 0.0 1.4 1 0 0 1 1 1 0 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term MGC-24 PF05283.11 KFX91633.1 - 0.11 13.0 0.3 0.23 11.9 0.3 1.7 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin EphA2_TM PF14575.6 KFX91633.1 - 0.18 12.7 0.0 0.33 11.9 0.0 1.4 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Gram_pos_anchor PF00746.21 KFX91633.1 - 0.94 9.5 3.8 3 7.9 3.8 1.8 1 1 0 1 1 1 0 LPXTG cell wall anchor motif Glyco_hydro_11 PF00457.17 KFX91634.1 - 7.1e-61 204.9 11.6 8.3e-61 204.7 11.6 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 11 His_Phos_1 PF00300.22 KFX91635.1 - 0.05 13.3 0.0 0.08 12.6 0.0 1.3 1 0 0 1 1 1 0 Histidine phosphatase superfamily (branch 1) Na_H_Exchanger PF00999.21 KFX91636.1 - 4e-73 246.4 36.8 5.2e-73 246.0 36.8 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family DUF5345 PF17280.2 KFX91636.1 - 1.6 8.7 4.7 0.83 9.7 0.5 2.6 2 0 0 2 2 2 0 Family of unknown function (DUF5345) MFS_2 PF13347.6 KFX91637.1 - 6.4e-09 34.9 1.0 6.4e-09 34.9 1.0 2.8 3 1 0 3 3 3 1 MFS/sugar transport protein PUCC PF03209.15 KFX91637.1 - 3e-06 26.5 1.9 5.4e-06 25.7 1.9 1.4 1 0 0 1 1 1 1 PUCC protein PKD PF00801.20 KFX91638.1 - 0.0057 16.5 8.4 7 6.6 3.9 3.6 1 1 1 2 2 2 2 PKD domain L51_S25_CI-B8 PF05047.16 KFX91638.1 - 0.31 11.0 1.3 16 5.5 0.1 3.0 1 1 2 3 3 3 0 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain Methyltransf_PK PF05891.12 KFX91639.1 - 1.2e-74 250.6 0.0 1.3e-74 250.4 0.0 1.0 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase Aldedh PF00171.22 KFX91640.1 - 8.6e-180 598.2 0.7 9.7e-180 598.0 0.7 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Zip PF02535.22 KFX91641.1 - 1.9e-51 175.3 3.3 2.5e-51 174.9 3.3 1.1 1 0 0 1 1 1 1 ZIP Zinc transporter Glyco_hydro_47 PF01532.20 KFX91642.1 - 2.9e-113 379.2 0.0 3.8e-113 378.8 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 GST_N PF02798.20 KFX91643.1 - 3.2e-11 43.4 0.0 6.1e-11 42.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KFX91643.1 - 1.9e-10 40.9 0.0 4.2e-10 39.8 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 KFX91643.1 - 5.9e-09 36.2 0.0 1e-08 35.4 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 KFX91643.1 - 0.00015 22.0 0.0 0.00039 20.6 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KFX91643.1 - 0.00032 20.8 0.0 0.00069 19.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 KFX91643.1 - 0.0016 18.4 0.0 0.0028 17.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain CRC_subunit PF08624.10 KFX91645.1 - 3.8e-53 179.6 0.0 5.6e-53 179.0 0.0 1.3 1 0 0 1 1 1 1 Chromatin remodelling complex Rsc7/Swp82 subunit DUF2370 PF10176.9 KFX91650.1 - 1.6e-83 279.8 6.0 2.5e-71 240.0 0.1 2.5 2 1 1 3 3 3 2 Protein of unknown function (DUF2370) SEEEED PF14797.6 KFX91650.1 - 0.055 13.6 5.6 0.1 12.8 5.6 1.3 1 0 0 1 1 1 0 Serine-rich region of AP3B1, clathrin-adaptor complex FAD_binding_3 PF01494.19 KFX91652.1 - 6e-20 71.8 0.5 2.8e-10 40.0 0.1 3.0 3 0 0 3 3 3 3 FAD binding domain DAO PF01266.24 KFX91652.1 - 2.7e-06 27.2 0.0 4.1e-06 26.6 0.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KFX91652.1 - 1.8e-05 24.8 0.1 3.9e-05 23.8 0.1 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 KFX91652.1 - 0.0064 17.0 0.1 0.41 11.2 0.1 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KFX91652.1 - 0.0098 15.0 0.2 0.016 14.3 0.2 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 KFX91652.1 - 0.084 12.1 0.1 0.32 10.2 0.0 1.9 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KFX91652.1 - 0.13 11.3 0.1 0.25 10.4 0.1 1.4 1 0 0 1 1 1 0 Lycopene cyclase protein NEMO PF11577.8 KFX91652.1 - 0.14 12.2 0.0 0.26 11.4 0.0 1.4 1 0 0 1 1 1 0 NF-kappa-B essential modulator NEMO Methyltransf_23 PF13489.6 KFX91653.1 - 2.3e-22 79.6 0.1 5.5e-22 78.3 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 KFX91653.1 - 2.3e-11 44.2 0.0 4.7e-11 43.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KFX91653.1 - 4.7e-09 36.8 0.0 9.3e-09 35.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KFX91653.1 - 2.4e-07 30.7 0.0 3.5e-06 26.9 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KFX91653.1 - 3.1e-06 27.9 0.0 1.7e-05 25.5 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_16 PF10294.9 KFX91653.1 - 0.0024 17.7 0.0 0.004 16.9 0.0 1.3 1 0 0 1 1 1 1 Lysine methyltransferase MTS PF05175.14 KFX91653.1 - 0.0027 17.3 0.0 0.0043 16.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_4 PF02390.17 KFX91653.1 - 0.034 13.6 0.0 0.064 12.7 0.0 1.4 1 0 0 1 1 1 0 Putative methyltransferase Methyltransf_2 PF00891.18 KFX91653.1 - 0.048 13.0 0.0 0.088 12.1 0.0 1.4 1 0 0 1 1 1 0 O-methyltransferase domain PrmA PF06325.13 KFX91653.1 - 0.079 12.3 0.0 0.12 11.7 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Ubie_methyltran PF01209.18 KFX91653.1 - 0.14 11.5 0.0 1.3 8.3 0.0 2.2 3 0 0 3 3 3 0 ubiE/COQ5 methyltransferase family ThrE PF06738.12 KFX91654.1 - 1.7e-17 63.6 25.4 2.9e-14 53.0 5.2 2.4 3 0 0 3 3 3 2 Putative threonine/serine exporter ThrE_2 PF12821.7 KFX91654.1 - 3.5e-11 43.3 19.6 7.9e-10 39.0 8.0 2.4 2 1 0 2 2 2 2 Threonine/Serine exporter, ThrE MIG-14_Wnt-bd PF06664.12 KFX91654.1 - 0.055 12.7 6.9 0.11 11.6 6.9 1.6 1 1 0 1 1 1 0 Wnt-binding factor required for Wnt secretion DUF373 PF04123.13 KFX91654.1 - 3.6 7.0 6.7 4.5 6.6 6.3 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF373) Forkhead PF00250.18 KFX91660.1 - 4.2e-35 119.9 0.1 8.6e-35 118.9 0.1 1.6 1 0 0 1 1 1 1 Forkhead domain Peptidase_S9 PF00326.21 KFX91661.1 - 0.11 12.0 0.0 0.15 11.5 0.0 1.2 1 0 0 1 1 1 0 Prolyl oligopeptidase family Apolipoprotein PF01442.18 KFX91662.1 - 7.9e-09 35.7 10.8 5.7e-07 29.6 7.6 3.2 1 1 1 2 2 2 2 Apolipoprotein A1/A4/E domain MHCassoc_trimer PF08831.10 KFX91662.1 - 4.1e-05 23.5 0.2 0.0091 16.0 0.0 3.1 2 1 1 3 3 3 1 Class II MHC-associated invariant chain trimerisation domain Gp-FAR-1 PF05823.12 KFX91662.1 - 0.00039 20.8 18.2 0.088 13.2 0.1 3.8 2 1 0 3 3 3 2 Nematode fatty acid retinoid binding protein (Gp-FAR-1) ApoLp-III PF07464.11 KFX91662.1 - 0.0021 18.1 19.6 0.06 13.4 2.3 4.4 1 1 2 3 3 3 1 Apolipophorin-III precursor (apoLp-III) HTH_48 PF17906.1 KFX91662.1 - 0.0058 16.7 0.7 2.3 8.4 0.0 3.8 4 0 0 4 4 4 1 HTH domain in Mos1 transposase Globin PF00042.22 KFX91662.1 - 0.027 15.0 2.2 1.9 9.0 0.1 3.2 3 1 0 4 4 3 0 Globin DUF883 PF05957.13 KFX91662.1 - 0.055 14.1 9.0 2.1 9.0 0.0 4.6 2 1 3 5 5 5 0 Bacterial protein of unknown function (DUF883) Peptidase_M41 PF01434.18 KFX91662.1 - 0.16 11.8 6.3 0.14 12.0 0.5 3.1 1 1 2 3 3 3 0 Peptidase family M41 DUF2523 PF10734.9 KFX91662.1 - 0.16 12.5 0.1 0.61 10.7 0.1 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF2523) ApoL PF05461.11 KFX91662.1 - 0.24 10.7 5.5 1.1 8.6 0.0 2.6 3 0 0 3 3 3 0 Apolipoprotein L FAM25 PF15825.5 KFX91662.1 - 0.36 11.2 13.8 0.64 10.4 0.5 3.8 3 1 0 3 3 3 0 FAM25 family Prominin PF05478.11 KFX91662.1 - 0.38 8.6 6.9 4.3 5.2 0.6 2.6 1 1 1 3 3 3 0 Prominin DHC PF09626.10 KFX91662.1 - 0.42 11.5 3.2 36 5.2 0.1 3.3 3 1 0 3 3 3 0 Dihaem cytochrome c Fib_alpha PF08702.10 KFX91662.1 - 0.75 10.0 8.2 23 5.2 0.2 3.6 1 1 2 4 4 4 0 Fibrinogen alpha/beta chain family CarD_CdnL_TRCF PF02559.16 KFX91662.1 - 7.5 7.3 11.8 30 5.4 3.1 4.2 1 1 2 3 3 3 0 CarD-like/TRCF domain BTB PF00651.31 KFX91668.1 - 3e-05 24.2 0.0 4.7e-05 23.6 0.0 1.2 1 0 0 1 1 1 1 BTB/POZ domain Glyco_hydro_28 PF00295.17 KFX91672.1 - 2.3e-38 132.1 7.6 3.2e-38 131.6 7.6 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 Beta_helix PF13229.6 KFX91672.1 - 0.017 15.0 6.3 0.027 14.3 6.3 1.3 1 0 0 1 1 1 0 Right handed beta helix region Glyco_hydro_28 PF00295.17 KFX91673.1 - 1.8e-41 142.2 16.6 2.3e-41 141.9 16.6 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 End_N_terminal PF12218.8 KFX91673.1 - 0.00023 20.8 0.2 0.00076 19.1 0.0 2.0 2 0 0 2 2 2 1 N terminal extension of bacteriophage endosialidase Pectinesterase PF01095.19 KFX91674.1 - 1.3e-48 165.2 8.1 1.7e-48 164.9 8.1 1.0 1 0 0 1 1 1 1 Pectinesterase Sugar_tr PF00083.24 KFX91675.1 - 5.8e-98 328.7 23.6 7e-98 328.4 23.6 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KFX91675.1 - 1.6e-29 102.9 30.0 2.3e-24 86.0 8.3 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily PUCC PF03209.15 KFX91675.1 - 1.9 7.4 14.8 0.047 12.7 6.5 2.3 3 0 0 3 3 3 0 PUCC protein Cpn60_TCP1 PF00118.24 KFX91676.1 - 2.6e-152 507.9 17.8 2.9e-152 507.7 17.8 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family HGTP_anticodon PF03129.20 KFX91677.1 - 3.8e-19 68.6 0.0 8.9e-19 67.4 0.0 1.7 1 0 0 1 1 1 1 Anticodon binding domain tRNA-synt_2b PF00587.25 KFX91677.1 - 3e-18 66.4 0.0 7.1e-18 65.2 0.0 1.6 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) ProRS-C_1 PF09180.11 KFX91677.1 - 4.7e-17 62.0 0.6 1.3e-16 60.5 0.6 1.7 1 0 0 1 1 1 1 Prolyl-tRNA synthetase, C-terminal GTP-bdg_M PF16360.5 KFX91679.1 - 0.012 16.2 1.4 0.03 14.9 1.4 1.9 1 1 0 1 1 1 0 GTP-binding GTPase Middle Region Ribosomal_L20 PF00453.18 KFX91679.1 - 0.019 15.1 0.1 0.029 14.4 0.1 1.3 1 0 0 1 1 1 0 Ribosomal protein L20 DUF2048 PF09752.9 KFX91679.1 - 0.024 13.7 0.0 0.025 13.7 0.0 1.2 1 0 0 1 1 1 0 Abhydrolase domain containing 18 ALG3 PF05208.13 KFX91680.1 - 1.2e-147 492.1 14.9 1.4e-147 491.9 14.9 1.0 1 0 0 1 1 1 1 ALG3 protein eIF-1a PF01176.19 KFX91681.1 - 5.7e-20 70.9 0.1 1.5e-19 69.6 0.0 1.7 2 0 0 2 2 2 1 Translation initiation factor 1A / IF-1 BCIP PF13862.6 KFX91683.1 - 2.8e-70 236.3 0.2 3.4e-70 236.0 0.2 1.1 1 0 0 1 1 1 1 p21-C-terminal region-binding protein LUC7 PF03194.15 KFX91688.1 - 2.5e-69 233.7 0.1 2.5e-69 233.7 0.1 2.2 2 0 0 2 2 2 1 LUC7 N_terminus DUF1241 PF06840.11 KFX91688.1 - 0.041 13.5 1.9 0.12 12.0 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1241) Abi_2 PF07751.11 KFX91688.1 - 6.8 6.9 7.6 0.79 10.0 0.4 2.3 2 0 0 2 2 2 0 Abi-like protein Gpi16 PF04113.14 KFX91689.1 - 2.4e-239 795.5 0.0 3e-239 795.1 0.0 1.0 1 0 0 1 1 1 1 Gpi16 subunit, GPI transamidase component DJ-1_PfpI PF01965.24 KFX91690.1 - 1.2e-14 54.5 0.0 1.8e-14 53.9 0.0 1.3 1 0 0 1 1 1 1 DJ-1/PfpI family ThiJ_like PF17124.5 KFX91690.1 - 0.0015 18.2 0.0 0.0024 17.6 0.0 1.2 1 0 0 1 1 1 1 ThiJ/PfpI family-like AAA PF00004.29 KFX91692.1 - 2.4e-17 63.6 0.0 4.6e-17 62.7 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.6 KFX91692.1 - 9.8e-13 48.2 0.0 4.1e-12 46.2 0.0 1.9 1 1 0 1 1 1 1 DNA polymerase III, delta subunit Rad17 PF03215.15 KFX91692.1 - 1.4e-09 38.1 0.0 2.8e-09 37.2 0.0 1.5 1 1 0 1 1 1 1 Rad17 P-loop domain AAA_30 PF13604.6 KFX91692.1 - 1.1e-07 31.8 0.3 3.6e-07 30.1 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_24 PF13479.6 KFX91692.1 - 4.9e-07 29.7 0.0 9.9e-07 28.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 KFX91692.1 - 1.8e-06 28.0 0.2 0.00014 21.7 0.0 2.3 1 1 1 2 2 2 1 AAA domain AAA_16 PF13191.6 KFX91692.1 - 2.1e-06 28.2 0.1 1.1e-05 25.9 0.1 2.4 1 1 0 1 1 1 1 AAA ATPase domain AAA_assoc_2 PF16193.5 KFX91692.1 - 2.6e-06 27.7 0.1 8.6e-06 26.0 0.0 1.9 2 0 0 2 2 1 1 AAA C-terminal domain AAA_22 PF13401.6 KFX91692.1 - 5.6e-06 26.7 0.0 1.9e-05 25.0 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.14 KFX91692.1 - 9.9e-06 25.6 0.5 3.5e-05 23.8 0.1 2.2 2 1 0 2 2 1 1 AAA domain (dynein-related subfamily) Rep_fac_C PF08542.11 KFX91692.1 - 1.3e-05 25.5 0.0 7.6e-05 23.0 0.0 2.3 2 0 0 2 2 2 1 Replication factor C C-terminal domain DNA_pol3_delta PF06144.13 KFX91692.1 - 2.1e-05 24.4 0.1 5.3e-05 23.1 0.1 1.6 2 0 0 2 2 2 1 DNA polymerase III, delta subunit DUF815 PF05673.13 KFX91692.1 - 2.2e-05 23.7 0.0 4.2e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) RuvB_N PF05496.12 KFX91692.1 - 3.9e-05 23.4 0.0 0.00017 21.3 0.0 2.0 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_3 PF07726.11 KFX91692.1 - 0.00029 20.7 0.1 0.0014 18.5 0.1 2.2 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 KFX91692.1 - 0.00031 20.5 0.0 0.00063 19.5 0.0 1.4 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA_14 PF13173.6 KFX91692.1 - 0.00041 20.4 0.0 0.00089 19.3 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KFX91692.1 - 0.00053 20.3 1.7 0.0015 18.9 0.1 2.3 2 2 0 2 2 2 1 AAA domain PhoH PF02562.16 KFX91692.1 - 0.0014 18.1 0.0 0.39 10.1 0.0 2.4 2 0 0 2 2 2 1 PhoH-like protein Mg_chelatase PF01078.21 KFX91692.1 - 0.0015 18.0 0.1 0.018 14.4 0.1 2.5 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI ResIII PF04851.15 KFX91692.1 - 0.007 16.4 0.0 0.14 12.1 0.0 2.2 1 1 0 2 2 2 1 Type III restriction enzyme, res subunit DUF2075 PF09848.9 KFX91692.1 - 0.0098 15.2 0.0 0.017 14.4 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_18 PF13238.6 KFX91692.1 - 0.013 16.1 0.0 0.023 15.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 KFX91692.1 - 0.014 15.7 0.0 0.025 14.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain DEAD PF00270.29 KFX91692.1 - 0.018 14.8 0.1 0.17 11.6 0.0 2.2 1 1 1 2 2 2 0 DEAD/DEAH box helicase TniB PF05621.11 KFX91692.1 - 0.019 14.4 0.0 0.12 11.8 0.0 2.1 1 1 0 1 1 1 0 Bacterial TniB protein AAA_25 PF13481.6 KFX91692.1 - 0.021 14.4 0.1 0.12 12.0 0.0 2.1 1 1 1 2 2 2 0 AAA domain AAA_7 PF12775.7 KFX91692.1 - 0.03 13.8 0.0 0.065 12.7 0.0 1.6 1 0 0 1 1 1 0 P-loop containing dynein motor region RNA_helicase PF00910.22 KFX91692.1 - 0.033 14.6 0.0 0.11 12.9 0.0 2.0 1 1 0 1 1 1 0 RNA helicase ATPase_2 PF01637.18 KFX91692.1 - 0.046 13.6 0.0 0.25 11.2 0.0 2.0 1 1 1 2 2 2 0 ATPase domain predominantly from Archaea NACHT PF05729.12 KFX91692.1 - 0.079 12.9 0.0 0.17 11.8 0.0 1.6 1 0 0 1 1 1 0 NACHT domain TK PF00265.18 KFX91692.1 - 0.079 12.8 0.0 0.18 11.6 0.0 1.6 1 0 0 1 1 1 0 Thymidine kinase IstB_IS21 PF01695.17 KFX91692.1 - 0.08 12.7 0.0 0.59 9.8 0.0 2.1 2 0 0 2 2 2 0 IstB-like ATP binding protein Fungal_trans PF04082.18 KFX91706.1 - 2.7e-09 36.5 0.0 7.7e-09 35.0 0.0 1.8 1 1 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.26 KFX91706.1 - 4.3e-09 36.3 9.2 4.6e-05 23.6 2.2 2.9 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_6 PF13912.6 KFX91706.1 - 1.7e-07 31.0 7.1 0.0071 16.3 1.7 3.6 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_4 PF13894.6 KFX91706.1 - 1.1e-06 29.0 9.6 0.0017 19.0 1.7 3.2 3 0 0 3 3 3 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KFX91706.1 - 1e-05 25.7 14.8 0.00014 22.1 3.7 4.2 4 0 0 4 4 4 2 Zinc-finger double domain zf-met PF12874.7 KFX91706.1 - 0.00015 22.0 4.3 0.057 13.8 0.3 3.3 3 0 0 3 3 3 2 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KFX91706.1 - 0.00015 21.9 1.7 0.32 11.3 0.3 2.8 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-C2H2_11 PF16622.5 KFX91706.1 - 0.067 13.0 0.6 3.1 7.6 0.1 2.9 2 0 0 2 2 2 0 zinc-finger C2H2-type DUF2197 PF09963.9 KFX91706.1 - 0.54 10.6 2.9 1.1 9.6 2.9 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2197) Methyltransf_25 PF13649.6 KFX91707.1 - 3.7e-09 37.2 0.1 2.5e-08 34.5 0.0 2.5 2 0 0 2 2 2 1 Methyltransferase domain Dala_Dala_lig_C PF07478.13 KFX91707.1 - 1.1e-08 34.9 0.0 3.1e-07 30.2 0.0 2.2 2 0 0 2 2 2 1 D-ala D-ala ligase C-terminus Methyltransf_11 PF08241.12 KFX91707.1 - 9.9e-07 29.3 0.0 4.8e-06 27.1 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 KFX91707.1 - 4.9e-06 26.4 0.0 1.3e-05 25.0 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain ATP-grasp_4 PF13535.6 KFX91707.1 - 1.5e-05 24.7 0.0 0.079 12.5 0.0 2.8 2 1 0 2 2 2 2 ATP-grasp domain ATP-grasp_3 PF02655.14 KFX91707.1 - 2.9e-05 24.1 0.0 0.00016 21.8 0.0 2.1 1 1 0 1 1 1 1 ATP-grasp domain Methyltransf_12 PF08242.12 KFX91707.1 - 0.00014 22.5 0.0 0.00039 21.1 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KFX91707.1 - 0.00027 20.8 0.0 0.00063 19.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KFX91707.1 - 0.0084 15.7 0.1 0.11 12.1 0.1 2.1 2 0 0 2 2 2 1 Methyltransferase small domain Cu_amine_oxid PF01179.20 KFX91708.1 - 1e-161 538.5 0.0 1.2e-161 538.2 0.0 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN3 PF02728.16 KFX91708.1 - 0.023 15.1 0.0 0.058 13.8 0.0 1.6 1 0 0 1 1 1 0 Copper amine oxidase, N3 domain Cu_amine_oxidN2 PF02727.16 KFX91708.1 - 0.037 14.3 0.0 0.087 13.1 0.0 1.7 1 0 0 1 1 1 0 Copper amine oxidase, N2 domain T5orf172 PF10544.9 KFX91713.1 - 7.8e-13 48.9 1.1 2e-12 47.5 1.1 1.7 1 0 0 1 1 1 1 T5orf172 domain MUG113 PF13455.6 KFX91713.1 - 1.5e-06 28.8 1.7 2.5e-06 28.1 1.1 1.7 2 0 0 2 2 2 1 Meiotically up-regulated gene 113 HC2 PF07382.11 KFX91713.1 - 0.0014 18.8 10.9 0.0026 17.9 10.9 1.3 1 0 0 1 1 1 1 Histone H1-like nucleoprotein HC2 Spore_coat_CotO PF14153.6 KFX91713.1 - 0.35 10.8 3.3 0.73 9.7 3.3 1.5 1 0 0 1 1 1 0 Spore coat protein CotO Na_H_Exchanger PF00999.21 KFX91723.1 - 2.3e-59 201.1 45.6 3.4e-59 200.6 45.6 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Usp PF00582.26 KFX91723.1 - 0.075 13.5 0.3 1.6 9.2 0.0 2.4 2 0 0 2 2 2 0 Universal stress protein family Mur_ligase_M PF08245.12 KFX91726.1 - 0.1 12.6 0.2 0.4 10.6 0.2 1.9 1 1 0 1 1 1 0 Mur ligase middle domain USP7_C2 PF14533.6 KFX91726.1 - 0.1 12.3 0.0 0.13 12.0 0.0 1.2 1 0 0 1 1 1 0 Ubiquitin-specific protease C-terminal Mur_ligase_C PF02875.21 KFX91727.1 - 0.00016 21.9 0.0 0.002 18.3 0.0 2.6 3 0 0 3 3 3 1 Mur ligase family, glutamate ligase domain Mur_ligase_M PF08245.12 KFX91727.1 - 0.00038 20.5 0.3 0.037 14.0 0.3 3.0 1 1 1 2 2 2 1 Mur ligase middle domain Mitofilin PF09731.9 KFX91728.1 - 4.6e-142 475.0 29.3 2.5e-125 419.8 20.2 2.3 2 1 1 3 3 3 2 Mitochondrial inner membrane protein TFIIS_M PF07500.14 KFX91728.1 - 0.0013 19.1 2.7 0.003 18.0 2.7 1.5 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS), central domain YqhG PF11079.8 KFX91728.1 - 0.078 11.9 1.1 0.13 11.2 1.1 1.3 1 0 0 1 1 1 0 Bacterial protein YqhG of unknown function PIN_8 PF18476.1 KFX91728.1 - 7.9 6.3 12.2 9.5 6.0 9.4 2.1 1 1 1 2 2 2 0 PIN like domain Ras PF00071.22 KFX91729.1 - 9.6e-59 197.6 0.3 1.1e-58 197.4 0.3 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFX91729.1 - 2.7e-36 124.4 0.1 5.8e-36 123.3 0.1 1.5 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFX91729.1 - 2.2e-15 56.5 0.1 2.7e-15 56.2 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 KFX91729.1 - 4.9e-07 29.3 0.0 5.9e-07 29.1 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 KFX91729.1 - 5.1e-07 29.4 0.0 7e-07 29.0 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 KFX91729.1 - 6e-07 29.5 0.0 9.6e-07 28.9 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KFX91729.1 - 6.5e-06 26.1 1.3 0.053 13.4 0.3 2.4 1 1 1 2 2 2 2 RsgA GTPase AAA_16 PF13191.6 KFX91729.1 - 0.0072 16.7 0.3 0.016 15.6 0.2 1.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 KFX91729.1 - 0.039 14.2 0.0 2.4 8.4 0.0 2.3 1 1 1 2 2 2 0 AAA domain AAT PF03417.16 KFX91729.1 - 0.12 12.0 0.1 0.19 11.4 0.1 1.3 1 0 0 1 1 1 0 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase Chromate_transp PF02417.15 KFX91743.1 - 2.2e-58 196.9 35.0 3.9e-34 118.1 12.7 2.5 3 0 0 3 3 3 2 Chromate transporter TPALS PF18178.1 KFX91743.1 - 0.053 13.0 0.0 0.12 11.8 0.0 1.5 2 0 0 2 2 2 0 TIR- and PNP-associating SLOG family CcmH PF03918.14 KFX91743.1 - 0.6 9.4 0.0 0.6 9.4 0.0 2.3 4 0 0 4 4 4 0 Cytochrome C biogenesis protein SPX PF03105.19 KFX91744.1 - 3.1 7.6 5.5 3.6 7.4 5.5 1.2 1 0 0 1 1 1 0 SPX domain Ank_2 PF12796.7 KFX91759.1 - 1.6e-78 259.3 0.0 2.3e-15 56.9 0.0 8.1 2 1 6 9 9 9 8 Ankyrin repeats (3 copies) SMK-1 PF04802.15 KFX91759.1 - 1.9e-77 259.4 0.2 4.8e-77 258.1 0.2 1.7 1 0 0 1 1 1 1 Component of IIS longevity pathway SMK-1 Ank_5 PF13857.6 KFX91759.1 - 4.8e-54 179.7 0.0 1.7e-07 31.3 0.1 11.8 3 3 8 11 11 11 11 Ankyrin repeats (many copies) Ank_4 PF13637.6 KFX91759.1 - 1.7e-52 175.2 0.0 8.9e-08 32.5 0.0 10.2 4 2 8 12 12 12 11 Ankyrin repeats (many copies) Ank PF00023.30 KFX91759.1 - 2.5e-47 157.3 0.0 3.3e-05 24.1 0.0 15.0 16 0 0 16 16 16 9 Ankyrin repeat Ank_3 PF13606.6 KFX91759.1 - 8.8e-44 142.5 0.0 0.00091 19.5 0.0 13.7 13 0 0 13 13 12 8 Ankyrin repeat NACHT PF05729.12 KFX91759.1 - 2.1e-06 27.8 1.4 5.8e-06 26.3 0.0 2.4 3 0 0 3 3 3 1 NACHT domain AAA_22 PF13401.6 KFX91759.1 - 2.1e-05 24.8 0.0 7e-05 23.1 0.0 1.9 1 0 0 1 1 1 1 AAA domain Helo_like_N PF17111.5 KFX91759.1 - 0.0018 17.7 1.0 0.0038 16.6 1.0 1.5 1 0 0 1 1 1 1 Fungal N-terminal domain of STAND proteins KAP_NTPase PF07693.14 KFX91759.1 - 0.03 13.5 2.0 0.66 9.1 0.0 2.3 1 1 1 2 2 2 0 KAP family P-loop domain Mg_chelatase PF01078.21 KFX91759.1 - 0.15 11.5 0.0 0.34 10.3 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Condensin2nSMC PF12422.8 KFX91759.1 - 0.16 12.2 1.4 0.47 10.6 0.3 2.4 2 0 0 2 2 2 0 Condensin II non structural maintenance of chromosomes subunit TauD PF02668.16 KFX91760.1 - 2.5e-57 194.7 1.1 3.5e-57 194.2 1.1 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Y_phosphatase3 PF13350.6 KFX91760.1 - 4e-05 23.7 0.0 7.8e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase PF00102.27 KFX91760.1 - 0.00041 20.0 0.0 0.0029 17.2 0.0 2.1 2 0 0 2 2 2 1 Protein-tyrosine phosphatase Y_phosphatase2 PF03162.13 KFX91760.1 - 0.0017 17.9 0.0 0.0033 17.0 0.0 1.4 1 0 0 1 1 1 1 Tyrosine phosphatase family TPR_19 PF14559.6 KFX91760.1 - 0.081 13.5 0.2 0.23 12.0 0.2 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat DSPc PF00782.20 KFX91760.1 - 0.13 12.0 0.0 0.29 10.9 0.0 1.5 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain Fungal_trans PF04082.18 KFX91761.1 - 1.1e-10 41.1 0.0 1.8e-10 40.3 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KFX91761.1 - 4.3e-09 36.3 7.1 8.6e-09 35.4 7.1 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Acetyltransf_1 PF00583.25 KFX91761.1 - 7.4e-07 29.4 0.0 1.5e-06 28.4 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KFX91761.1 - 0.00024 21.4 0.0 0.00056 20.3 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KFX91761.1 - 0.0015 18.5 0.0 0.0031 17.4 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain NYD-SP12_N PF15015.6 KFX91761.1 - 0.2 10.0 0.1 0.31 9.3 0.1 1.2 1 0 0 1 1 1 0 Spermatogenesis-associated, N-terminal adh_short PF00106.25 KFX91762.1 - 5.2e-41 140.2 0.4 6.3e-41 140.0 0.4 1.0 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KFX91762.1 - 2.7e-32 112.2 1.1 4.1e-32 111.6 1.1 1.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KFX91762.1 - 8.9e-17 61.6 0.1 1.1e-16 61.3 0.1 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KFX91762.1 - 3.4e-06 26.7 0.8 3.1e-05 23.6 0.8 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 KFX91762.1 - 1.5e-05 24.3 0.0 2.4e-05 23.6 0.0 1.3 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein Shikimate_DH PF01488.20 KFX91762.1 - 0.0026 17.8 0.2 0.0041 17.2 0.2 1.2 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase GDP_Man_Dehyd PF16363.5 KFX91762.1 - 0.0033 16.9 0.3 0.12 11.8 0.0 2.1 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase Sacchrp_dh_NADP PF03435.18 KFX91762.1 - 0.006 16.8 0.3 0.0099 16.1 0.3 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain PA PF02225.22 KFX91762.1 - 0.097 12.7 0.1 0.19 11.8 0.1 1.5 1 0 0 1 1 1 0 PA domain Pkinase PF00069.25 KFX91769.1 - 1.9e-35 122.5 0.0 2.4e-35 122.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFX91769.1 - 2.3e-17 63.1 0.0 3.5e-17 62.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KFX91769.1 - 0.00077 18.4 0.0 0.0013 17.6 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KFX91769.1 - 0.0037 17.2 0.1 0.016 15.1 0.1 1.8 1 1 1 2 2 2 1 Phosphotransferase enzyme family VIR_N PF15912.5 KFX91769.1 - 2.5 7.6 4.7 4.2 6.9 4.7 1.2 1 0 0 1 1 1 0 Virilizer, N-terminal muHD PF10291.9 KFX91770.1 - 2.5e-58 197.6 0.0 4.6e-58 196.7 0.0 1.4 1 0 0 1 1 1 1 Muniscin C-terminal mu homology domain FCH PF00611.23 KFX91770.1 - 4.7e-08 33.2 0.0 1.9e-07 31.2 0.0 2.1 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain PTRF_SDPR PF15237.6 KFX91770.1 - 0.03 13.9 1.1 0.083 12.5 1.1 1.7 1 0 0 1 1 1 0 PTRF/SDPR family Muted PF14942.6 KFX91770.1 - 0.073 13.4 2.7 0.2 12.0 2.7 1.7 1 0 0 1 1 1 0 Organelle biogenesis, Muted-like protein Fis1_TPR_C PF14853.6 KFX91770.1 - 0.097 12.8 0.2 0.22 11.6 0.2 1.5 1 0 0 1 1 1 0 Fis1 C-terminal tetratricopeptide repeat Prim-Pol PF09250.11 KFX91771.1 - 0.07 13.5 0.1 0.13 12.7 0.1 1.4 1 0 0 1 1 1 0 Bifunctional DNA primase/polymerase, N-terminal Septin PF00735.18 KFX91776.1 - 1.8e-73 247.3 0.1 2e-73 247.1 0.1 1.0 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.23 KFX91776.1 - 4e-08 33.4 0.0 5.5e-08 32.9 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 KFX91776.1 - 1.3e-06 28.1 0.7 3.4e-05 23.5 0.1 2.2 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 KFX91776.1 - 2.5e-06 27.5 0.5 1.9e-05 24.7 0.1 2.2 2 1 0 2 2 2 1 RsgA GTPase AAA_22 PF13401.6 KFX91776.1 - 0.00077 19.8 0.1 0.0016 18.7 0.1 1.7 1 1 0 1 1 1 1 AAA domain Pox_A32 PF04665.12 KFX91776.1 - 0.0013 18.2 0.1 0.0021 17.5 0.1 1.2 1 0 0 1 1 1 1 Poxvirus A32 protein Roc PF08477.13 KFX91776.1 - 0.0015 18.8 0.1 0.0023 18.1 0.1 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase AIG1 PF04548.16 KFX91776.1 - 0.0022 17.4 0.0 0.0028 17.0 0.0 1.2 1 0 0 1 1 1 1 AIG1 family IIGP PF05049.13 KFX91776.1 - 0.0035 16.5 0.0 0.0045 16.1 0.0 1.2 1 0 0 1 1 1 1 Interferon-inducible GTPase (IIGP) Dynamin_N PF00350.23 KFX91776.1 - 0.0082 16.2 0.4 1.6 8.8 0.0 2.2 1 1 1 2 2 2 1 Dynamin family AAA_24 PF13479.6 KFX91776.1 - 0.0085 15.8 0.3 0.011 15.5 0.3 1.4 1 1 0 1 1 1 1 AAA domain Ras PF00071.22 KFX91776.1 - 0.012 15.2 0.4 0.027 14.1 0.4 1.6 1 1 0 1 1 1 0 Ras family AAA_16 PF13191.6 KFX91776.1 - 0.012 16.0 0.0 0.021 15.2 0.0 1.6 1 1 0 1 1 1 0 AAA ATPase domain T2SSE PF00437.20 KFX91776.1 - 0.025 13.7 0.1 0.04 13.0 0.1 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein KAP_NTPase PF07693.14 KFX91776.1 - 0.025 13.8 0.0 0.025 13.8 0.0 1.1 1 0 0 1 1 1 0 KAP family P-loop domain NACHT PF05729.12 KFX91776.1 - 0.028 14.4 0.0 0.043 13.7 0.0 1.3 1 0 0 1 1 1 0 NACHT domain PduV-EutP PF10662.9 KFX91776.1 - 0.036 13.8 0.5 1.8 8.3 0.4 2.5 2 1 0 2 2 1 0 Ethanolamine utilisation - propanediol utilisation Sigma54_activat PF00158.26 KFX91776.1 - 0.04 13.6 0.0 0.06 13.0 0.0 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain ABC_tran PF00005.27 KFX91776.1 - 0.059 13.9 0.0 0.083 13.4 0.0 1.3 1 0 0 1 1 1 0 ABC transporter ATP_bind_1 PF03029.17 KFX91776.1 - 0.06 13.1 0.7 5.7 6.6 0.1 2.4 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein FtsK_SpoIIIE PF01580.18 KFX91776.1 - 0.073 12.4 0.0 0.11 11.8 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_25 PF13481.6 KFX91776.1 - 0.074 12.6 0.1 0.12 11.9 0.0 1.6 2 1 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 KFX91776.1 - 0.075 13.4 0.1 0.18 12.2 0.0 1.7 2 1 0 2 2 1 0 RNA helicase FeoB_N PF02421.18 KFX91776.1 - 0.13 11.8 0.2 0.41 10.2 0.2 1.8 1 1 0 1 1 1 0 Ferrous iron transport protein B WD40 PF00400.32 KFX91777.1 - 6.3e-43 143.9 27.8 3.9e-09 37.0 0.3 13.6 14 0 0 14 14 14 7 WD domain, G-beta repeat Utp12 PF04003.12 KFX91777.1 - 3.3e-25 88.5 0.0 5.3e-25 87.8 0.0 1.3 1 0 0 1 1 1 1 Dip2/Utp12 Family ANAPC4_WD40 PF12894.7 KFX91777.1 - 6.8e-23 80.8 0.0 0.041 14.2 0.0 9.8 4 1 5 10 10 10 6 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KFX91777.1 - 4.6e-09 35.7 0.2 0.8 8.6 0.0 5.5 3 2 2 5 5 5 3 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 KFX91777.1 - 1.8e-07 31.3 3.8 0.079 12.8 0.1 5.6 5 1 1 6 6 6 2 Eukaryotic translation initiation factor eIF2A WD40_like PF17005.5 KFX91777.1 - 8.2e-05 22.1 0.0 1.8 7.8 0.0 3.6 3 0 0 3 3 3 2 WD40-like domain Nup160 PF11715.8 KFX91777.1 - 0.0042 15.8 5.0 2.2 6.8 0.1 3.9 2 2 1 3 3 3 3 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.16 KFX91777.1 - 0.021 13.3 0.0 1.2 7.6 0.0 3.1 2 1 0 3 3 3 0 Cytochrome D1 heme domain Nbas_N PF15492.6 KFX91777.1 - 0.024 14.0 0.1 3.4 6.9 0.0 2.9 3 0 0 3 3 3 0 Neuroblastoma-amplified sequence, N terminal PALB2_WD40 PF16756.5 KFX91777.1 - 0.055 12.4 0.0 4.7 6.0 0.0 2.9 3 0 0 3 3 3 0 Partner and localizer of BRCA2 WD40 domain PQQ_3 PF13570.6 KFX91777.1 - 0.1 13.2 3.7 25 5.5 0.3 5.0 5 0 0 5 5 4 0 PQQ-like domain IBN_N PF03810.19 KFX91778.1 - 4e-12 45.9 0.1 5.8e-11 42.2 0.0 2.7 2 0 0 2 2 2 1 Importin-beta N-terminal domain Cse1 PF08506.10 KFX91778.1 - 5.8e-05 22.1 0.1 0.00013 20.9 0.1 1.6 1 0 0 1 1 1 1 Cse1 RTP1_C1 PF10363.9 KFX91778.1 - 0.029 14.6 0.2 0.54 10.5 0.1 3.0 3 0 0 3 3 3 0 Required for nuclear transport of RNA pol II C-terminus 1 GRIP PF01465.20 KFX91778.1 - 0.037 13.9 0.1 0.31 11.0 0.1 2.7 1 1 0 1 1 1 0 GRIP domain Vac14_Fab1_bd PF12755.7 KFX91778.1 - 0.093 13.3 1.6 3.9 8.1 0.1 3.5 3 0 0 3 3 3 0 Vacuolar 14 Fab1-binding region Xpo1 PF08389.12 KFX91778.1 - 0.35 10.9 5.1 11 6.0 0.0 4.8 7 0 0 7 7 7 0 Exportin 1-like protein HEAT_EZ PF13513.6 KFX91778.1 - 1.2 9.7 3.9 29 5.3 0.7 4.5 4 1 0 4 4 4 0 HEAT-like repeat Presenilin PF01080.17 KFX91779.1 - 0.62 8.8 37.7 0.71 8.6 37.7 1.1 1 0 0 1 1 1 0 Presenilin MFS_1 PF07690.16 KFX91781.1 - 1.2e-40 139.5 98.0 3.3e-37 128.2 60.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Epimerase PF01370.21 KFX91782.1 - 7.8e-14 51.7 0.0 5.6e-13 48.9 0.0 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KFX91782.1 - 7.6e-11 41.5 0.0 1.1e-10 41.1 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 KFX91782.1 - 1.4e-10 41.1 0.0 1.9e-10 40.6 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.6 KFX91782.1 - 1.6e-09 37.9 0.1 2.4e-09 37.3 0.1 1.3 1 0 0 1 1 1 1 NAD(P)H-binding NAD_binding_4 PF07993.12 KFX91782.1 - 1.7e-08 34.0 0.1 1.3e-07 31.1 0.1 2.0 1 1 0 1 1 1 1 Male sterility protein Polysacc_synt_2 PF02719.15 KFX91782.1 - 3.8e-05 23.0 0.1 5.8e-05 22.4 0.1 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein adh_short PF00106.25 KFX91782.1 - 0.00058 19.4 0.1 0.00089 18.8 0.1 1.4 1 0 0 1 1 1 1 short chain dehydrogenase NmrA PF05368.13 KFX91782.1 - 0.0016 18.1 0.2 0.0026 17.4 0.2 1.3 1 0 0 1 1 1 1 NmrA-like family KR PF08659.10 KFX91782.1 - 0.0058 16.6 0.4 0.022 14.7 0.4 2.1 1 1 0 1 1 1 1 KR domain Glyco_hydro_18 PF00704.28 KFX91785.1 - 1.6e-51 175.9 4.6 1.6e-51 175.9 4.6 1.7 2 0 0 2 2 2 1 Glycosyl hydrolases family 18 Chitin_bind_1 PF00187.19 KFX91785.1 - 5.5e-20 71.6 100.4 6.7e-08 32.9 12.9 4.8 4 0 0 4 4 4 4 Chitin recognition protein PIG-L PF02585.17 KFX91786.1 - 0.033 14.8 0.0 0.043 14.4 0.0 1.2 1 0 0 1 1 1 0 GlcNAc-PI de-N-acetylase Proteasome PF00227.26 KFX91787.1 - 2.7e-49 167.3 0.0 3.7e-49 166.8 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 KFX91787.1 - 4.9e-13 48.5 0.3 8.3e-13 47.8 0.3 1.4 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature SCP2 PF02036.17 KFX91787.1 - 0.037 14.5 0.0 0.07 13.6 0.0 1.5 1 0 0 1 1 1 0 SCP-2 sterol transfer family DUF2373 PF10180.9 KFX91788.1 - 1.2e-21 76.3 0.2 3.5e-21 74.8 0.1 1.9 2 0 0 2 2 2 1 Uncharacterised conserved protein (DUF2373) Methyltransf_1N PF02870.15 KFX91788.1 - 0.077 13.8 0.2 1.1 10.1 0.1 2.7 2 0 0 2 2 2 0 6-O-methylguanine DNA methyltransferase, ribonuclease-like domain Vps62 PF06101.11 KFX91789.1 - 8.6e-11 40.8 0.5 1.7e-10 39.9 0.5 1.4 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 62 DnaJ_C PF01556.18 KFX91790.1 - 1.6e-28 99.7 0.0 2.5e-28 99.0 0.0 1.3 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 KFX91790.1 - 5.1e-25 87.4 0.9 8.1e-25 86.7 0.9 1.3 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 KFX91790.1 - 1.2e-14 54.4 13.7 2.1e-14 53.6 13.7 1.4 1 0 0 1 1 1 1 DnaJ central domain Anti-TRAP PF15777.5 KFX91790.1 - 0.00012 21.9 3.4 0.063 13.2 0.5 2.4 2 0 0 2 2 2 2 Tryptophan RNA-binding attenuator protein inhibitory protein HypA PF01155.19 KFX91790.1 - 0.0061 16.6 6.4 0.37 10.8 0.8 2.2 2 0 0 2 2 2 2 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Lar_restr_allev PF14354.6 KFX91790.1 - 2.9 8.3 6.9 3.6 8.1 1.4 2.8 1 1 1 2 2 2 0 Restriction alleviation protein Lar HA2 PF04408.23 KFX91791.1 - 3.6e-20 72.2 0.1 3.6e-20 72.2 0.1 3.9 3 1 0 3 3 2 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 KFX91791.1 - 3.5e-19 69.0 0.0 7.3e-19 67.9 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 KFX91791.1 - 2.6e-14 53.5 0.0 8.5e-14 51.8 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_22 PF13401.6 KFX91791.1 - 1.8e-05 25.0 0.0 5.4e-05 23.5 0.0 1.8 1 0 0 1 1 1 1 AAA domain DEAD PF00270.29 KFX91791.1 - 2.7e-05 24.0 0.0 7.5e-05 22.6 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_30 PF13604.6 KFX91791.1 - 0.00058 19.6 0.1 0.00058 19.6 0.1 2.3 2 0 0 2 2 2 1 AAA domain T2SSE PF00437.20 KFX91791.1 - 0.0024 17.0 0.0 0.0055 15.8 0.0 1.6 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_19 PF13245.6 KFX91791.1 - 0.021 15.1 0.1 0.056 13.8 0.1 1.7 1 0 0 1 1 1 0 AAA domain SRP54 PF00448.22 KFX91791.1 - 0.022 14.4 0.1 0.051 13.2 0.1 1.7 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain ABC_tran PF00005.27 KFX91791.1 - 0.056 14.0 1.6 0.15 12.6 0.0 2.5 2 1 0 2 2 2 0 ABC transporter AAA_23 PF13476.6 KFX91791.1 - 0.23 11.9 0.1 0.23 11.9 0.1 3.5 1 1 1 2 2 1 0 AAA domain AAA_14 PF13173.6 KFX91791.1 - 0.37 10.8 1.6 2.8 8.0 0.1 2.8 2 1 0 2 2 2 0 AAA domain UTP15_C PF09384.10 KFX91792.1 - 5.2e-53 178.7 0.0 8.9e-53 177.9 0.0 1.4 1 0 0 1 1 1 1 UTP15 C terminal WD40 PF00400.32 KFX91792.1 - 7.4e-20 70.9 1.3 0.00027 21.6 0.0 5.7 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFX91792.1 - 6.7e-07 29.5 0.2 0.32 11.3 0.0 4.6 3 2 3 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain WD40_3 PF15911.5 KFX91792.1 - 0.061 13.3 0.0 5.2 7.1 0.0 2.8 2 0 0 2 2 2 0 WD domain, G-beta repeat Nup160 PF11715.8 KFX91792.1 - 0.084 11.5 0.1 8.6 4.9 0.1 2.2 1 1 1 2 2 2 0 Nucleoporin Nup120/160 Nbas_N PF15492.6 KFX91792.1 - 0.15 11.4 0.0 2.3 7.5 0.0 2.2 2 0 0 2 2 2 0 Neuroblastoma-amplified sequence, N terminal RRM_1 PF00076.22 KFX91793.1 - 1.1e-32 111.7 0.2 5.9e-15 54.9 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KFX91793.1 - 1.2e-10 41.4 0.2 0.00033 20.7 0.0 2.7 2 0 0 2 2 2 2 RNA recognition motif RRM_3 PF08777.11 KFX91793.1 - 0.0067 16.5 0.1 1.3 9.1 0.0 2.6 2 0 0 2 2 2 2 RNA binding motif Nup35_RRM_2 PF14605.6 KFX91793.1 - 0.07 13.1 0.0 3.4 7.7 0.0 2.3 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif GEMIN8 PF15348.6 KFX91793.1 - 0.091 13.0 4.4 0.25 11.6 4.4 1.7 1 0 0 1 1 1 0 Gemini of Cajal bodies-associated protein 8 RabGAP-TBC PF00566.18 KFX91794.1 - 2.8e-49 167.7 0.0 6e-49 166.6 0.0 1.5 1 1 0 1 1 1 1 Rab-GTPase-TBC domain MRC1 PF09444.10 KFX91795.1 - 1.6e-43 148.7 22.0 1.6e-43 148.7 22.0 8.8 5 2 1 7 7 7 1 MRC1-like domain MFS_MOT1 PF16983.5 KFX91796.1 - 4.4e-64 213.8 29.0 1.3e-34 118.9 10.3 2.4 2 0 0 2 2 2 2 Molybdate transporter of MFS superfamily Sulfate_transp PF00916.20 KFX91796.1 - 1.8e-05 23.7 19.4 0.019 13.7 19.4 2.6 1 1 0 1 1 1 1 Sulfate permease family SPC12 PF06645.13 KFX91796.1 - 5.9 7.1 10.8 0.18 11.9 0.4 3.5 4 0 0 4 4 4 0 Microsomal signal peptidase 12 kDa subunit (SPC12) Peptidase_M43 PF05572.13 KFX91797.1 - 1.9e-14 53.9 0.0 3e-14 53.2 0.0 1.4 1 0 0 1 1 1 1 Pregnancy-associated plasma protein-A Reprolysin_3 PF13582.6 KFX91797.1 - 3.1e-05 24.5 0.0 6.5e-05 23.4 0.0 1.6 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.6 KFX91797.1 - 0.0011 19.2 1.3 0.017 15.3 1.2 2.3 1 1 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_4 PF13583.6 KFX91797.1 - 0.013 15.2 0.3 0.75 9.4 0.0 2.2 2 0 0 2 2 2 0 Metallo-peptidase family M12B Reprolysin-like Cutinase PF01083.22 KFX91805.1 - 0.00032 20.7 0.0 0.00069 19.6 0.0 1.6 1 0 0 1 1 1 1 Cutinase Palm_thioest PF02089.15 KFX91805.1 - 0.0011 18.8 0.0 0.0018 18.1 0.0 1.3 1 0 0 1 1 1 1 Palmitoyl protein thioesterase PGAP1 PF07819.13 KFX91805.1 - 0.0021 17.8 0.0 0.0039 17.0 0.0 1.4 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_6 PF12697.7 KFX91805.1 - 0.0034 18.0 0.0 0.0049 17.5 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF676 PF05057.14 KFX91805.1 - 0.039 13.5 0.0 0.063 12.8 0.0 1.3 1 0 0 1 1 1 0 Putative serine esterase (DUF676) DUF726 PF05277.12 KFX91805.1 - 0.043 12.7 0.0 0.066 12.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF726) LIDHydrolase PF10230.9 KFX91805.1 - 0.054 13.1 0.0 0.1 12.2 0.0 1.4 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase Aurora-A_bind PF09041.10 KFX91805.1 - 0.13 12.3 0.2 0.38 10.9 0.2 1.7 1 0 0 1 1 1 0 Aurora-A binding Thioesterase PF00975.20 KFX91805.1 - 0.14 12.3 0.0 0.27 11.3 0.0 1.5 1 0 0 1 1 1 0 Thioesterase domain Hydrolase_4 PF12146.8 KFX91805.1 - 0.16 11.2 0.0 0.26 10.5 0.0 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 FYVE PF01363.21 KFX91805.1 - 0.34 11.1 19.6 0.036 14.2 4.6 2.5 1 1 1 2 2 2 0 FYVE zinc finger zinc-ribbons_6 PF07191.12 KFX91805.1 - 8.8 6.4 17.5 8.2 6.5 4.9 2.3 2 0 0 2 2 2 0 zinc-ribbons SMC_N PF02463.19 KFX91814.1 - 2.1e-67 226.8 11.3 1.1e-66 224.5 11.3 2.3 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 KFX91814.1 - 2e-21 76.5 1.2 9.9e-21 74.2 0.3 2.6 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain AAA_23 PF13476.6 KFX91814.1 - 2.3e-12 47.8 8.3 2.3e-12 47.8 8.3 6.6 2 2 3 5 5 2 1 AAA domain AAA_21 PF13304.6 KFX91814.1 - 5.4e-10 39.6 1.9 0.00063 19.7 0.0 3.3 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system Lebercilin PF15619.6 KFX91814.1 - 0.00059 19.6 7.8 0.00059 19.6 7.8 6.6 2 2 3 5 5 4 1 Ciliary protein causing Leber congenital amaurosis disease AAA_29 PF13555.6 KFX91814.1 - 0.001 18.7 0.1 0.0024 17.6 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain ATG16 PF08614.11 KFX91814.1 - 0.0038 17.5 26.5 0.0038 17.5 26.5 6.5 4 3 3 7 7 7 2 Autophagy protein 16 (ATG16) XhlA PF10779.9 KFX91814.1 - 0.0061 16.7 4.1 0.0061 16.7 4.1 8.3 8 2 1 10 10 9 2 Haemolysin XhlA HIP1_clath_bdg PF16515.5 KFX91814.1 - 0.01 16.5 8.3 0.01 16.5 8.3 9.6 3 2 3 8 8 7 1 Clathrin-binding domain of Huntingtin-interacting protein 1 ABC_tran PF00005.27 KFX91814.1 - 0.15 12.5 0.0 0.15 12.5 0.0 6.2 4 2 0 4 4 2 0 ABC transporter NRN1 PF15056.6 KFX91814.1 - 0.68 10.1 3.1 1.3 9.2 0.4 3.0 2 0 0 2 2 2 0 Neuritin protein family DUF2015 PF09435.10 KFX91814.1 - 1.5 8.7 6.1 0.61 10.0 0.3 3.3 3 0 0 3 3 3 0 Fungal protein of unknown function (DUF2015) 4HBT PF03061.22 KFX91815.1 - 1.3e-13 51.1 0.0 1.9e-13 50.6 0.0 1.3 1 0 0 1 1 1 1 Thioesterase superfamily 4HBT_3 PF13622.6 KFX91815.1 - 1.6e-05 25.3 0.0 2.3e-05 24.8 0.0 1.2 1 0 0 1 1 1 1 Thioesterase-like superfamily HupF_HypC PF01455.18 KFX91815.1 - 0.12 12.6 0.0 0.23 11.6 0.0 1.6 1 0 0 1 1 1 0 HupF/HypC family MOSC PF03473.17 KFX91816.1 - 6.3e-26 90.9 0.0 1.6e-25 89.6 0.0 1.7 2 0 0 2 2 2 1 MOSC domain MOSC_N PF03476.16 KFX91816.1 - 3.1e-12 46.4 0.0 5.8e-12 45.5 0.0 1.4 1 0 0 1 1 1 1 MOSC N-terminal beta barrel domain FA_desaturase PF00487.24 KFX91817.1 - 9.5e-19 68.2 13.8 9.5e-19 68.2 13.8 1.4 1 1 0 1 1 1 1 Fatty acid desaturase Cyt-b5 PF00173.28 KFX91817.1 - 1.5e-16 60.3 0.3 3.9e-16 58.9 0.1 1.8 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain DUF1189 PF06691.11 KFX91817.1 - 0.11 12.1 0.4 0.39 10.3 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1189) Kei1 PF08552.11 KFX91820.1 - 1.6e-11 44.5 0.5 1.6e-11 44.5 0.5 1.7 2 0 0 2 2 2 1 Inositolphosphorylceramide synthase subunit Kei1 TRAM1 PF08390.11 KFX91820.1 - 0.0048 16.5 0.4 0.0081 15.8 0.2 1.4 1 1 0 1 1 1 1 TRAM1-like protein Nop53 PF07767.11 KFX91821.1 - 1.6e-106 357.0 27.8 2.1e-106 356.7 27.8 1.1 1 0 0 1 1 1 1 Nop53 (60S ribosomal biogenesis) Ras PF00071.22 KFX91822.1 - 3.2e-59 199.1 0.3 4.2e-59 198.8 0.3 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFX91822.1 - 1.2e-36 125.5 0.1 2.1e-36 124.8 0.1 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFX91822.1 - 9.4e-18 64.3 0.2 1.2e-17 64.0 0.2 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KFX91822.1 - 3.6e-06 26.6 0.1 2.2e-05 24.1 0.1 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 KFX91822.1 - 3e-05 24.1 0.0 6.5e-05 23.0 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 KFX91822.1 - 5.3e-05 22.7 0.0 8.7e-05 22.0 0.0 1.3 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 KFX91822.1 - 6.8e-05 22.3 0.3 8.9e-05 21.9 0.3 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 KFX91822.1 - 0.00033 20.6 0.1 0.2 11.6 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase TIR_2 PF13676.6 KFX91822.1 - 0.088 13.4 0.0 0.16 12.5 0.0 1.4 1 0 0 1 1 1 0 TIR domain DprA_WH PF17782.1 KFX91824.1 - 0.0092 16.1 0.6 9.2 6.5 0.0 3.9 3 1 1 4 4 4 1 DprA winged helix domain Rubredoxin PF00301.20 KFX91824.1 - 0.057 13.4 0.1 0.13 12.3 0.1 1.5 1 0 0 1 1 1 0 Rubredoxin DUF3926 PF13080.6 KFX91824.1 - 3.7 7.6 9.5 44 4.1 0.1 4.0 4 0 0 4 4 4 0 Protein of unknown function (DUF3926) GDI PF00996.18 KFX91825.1 - 1.3e-186 620.3 0.0 1.6e-186 620.1 0.0 1.1 1 0 0 1 1 1 1 GDP dissociation inhibitor MRP-L47 PF06984.13 KFX91825.1 - 1.3e-20 73.3 0.3 2.5e-20 72.4 0.3 1.5 1 0 0 1 1 1 1 Mitochondrial 39-S ribosomal protein L47 (MRP-L47) NAD_binding_8 PF13450.6 KFX91825.1 - 0.065 13.5 0.1 0.17 12.2 0.1 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 KFX91825.1 - 0.16 12.5 0.2 0.87 10.2 0.1 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase zf-H2C2_2 PF13465.6 KFX91826.1 - 3.1e-06 27.3 7.1 9.2e-06 25.9 1.1 3.0 2 0 0 2 2 2 1 Zinc-finger double domain zf-Di19 PF05605.12 KFX91826.1 - 0.00077 19.7 4.1 0.0015 18.8 4.1 1.4 1 0 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_4 PF13894.6 KFX91826.1 - 0.0014 19.3 14.7 0.12 13.2 5.5 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger DUF3464 PF11947.8 KFX91826.1 - 0.046 13.5 6.0 2.4 7.9 0.0 2.4 2 0 0 2 2 2 0 Photosynthesis affected mutant 68 zf-C2H2_jaz PF12171.8 KFX91826.1 - 0.12 12.7 3.0 11 6.5 0.8 2.6 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding TERB2 PF15101.6 KFX91826.1 - 0.33 11.0 6.6 14 5.6 7.9 2.3 2 0 0 2 2 2 0 Telomere-associated protein TERB2 DivIC PF04977.15 KFX91826.1 - 6.7 6.6 11.1 12 5.8 11.1 1.3 1 0 0 1 1 1 0 Septum formation initiator V-ATPase_H_N PF03224.14 KFX91828.1 - 8.4e-56 189.5 0.0 1.2e-55 189.0 0.0 1.2 1 0 0 1 1 1 1 V-ATPase subunit H V-ATPase_H_C PF11698.8 KFX91828.1 - 9e-37 125.8 0.0 1.8e-36 124.8 0.0 1.5 1 0 0 1 1 1 1 V-ATPase subunit H Methyltr_RsmB-F PF01189.17 KFX91845.1 - 2.2e-13 50.3 0.2 2.5e-07 30.5 0.1 3.2 2 1 0 2 2 2 2 16S rRNA methyltransferase RsmB/F DUF1682 PF07946.14 KFX91847.1 - 0.75 8.9 15.5 1.2 8.3 15.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) DUF2070 PF09843.9 KFX91849.1 - 0.87 7.8 6.1 1.2 7.4 6.1 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) AP_endonuc_2 PF01261.24 KFX91850.1 - 9.2e-32 110.2 0.0 1.3e-31 109.7 0.0 1.2 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel DDE_1 PF03184.19 KFX91857.1 - 5e-11 42.6 0.2 9.2e-11 41.7 0.0 1.6 2 0 0 2 2 2 1 DDE superfamily endonuclease Trypan_PARP PF05887.11 KFX91857.1 - 0.65 10.0 6.7 1.2 9.1 6.7 1.4 1 1 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Ank_2 PF12796.7 KFX91858.1 - 4.7e-29 100.8 0.1 3.5e-09 37.1 0.0 3.1 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KFX91858.1 - 5.5e-26 90.6 0.9 3.6e-08 33.8 0.1 3.6 3 0 0 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 KFX91858.1 - 1.9e-21 75.9 2.9 5.9e-06 26.4 0.1 3.7 4 0 0 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.30 KFX91858.1 - 8.2e-18 64.0 2.9 0.00045 20.5 0.0 6.0 6 0 0 6 6 6 3 Ankyrin repeat Ank_3 PF13606.6 KFX91858.1 - 4.9e-17 60.3 2.3 0.023 15.2 0.0 6.1 6 0 0 6 6 6 5 Ankyrin repeat F-box-like PF12937.7 KFX91858.1 - 4.5e-06 26.5 0.1 1.1e-05 25.3 0.1 1.6 1 0 0 1 1 1 1 F-box-like F-box_4 PF15966.5 KFX91858.1 - 0.062 13.2 0.0 0.11 12.4 0.0 1.3 1 0 0 1 1 1 0 F-box F-box PF00646.33 KFX91858.1 - 0.14 12.0 0.0 0.28 11.1 0.0 1.4 1 0 0 1 1 1 0 F-box domain p450 PF00067.22 KFX91860.1 - 9.7e-07 27.9 0.0 1.5e-06 27.3 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 BAR PF03114.18 KFX91869.1 - 5.6e-49 166.9 5.7 7.4e-49 166.5 5.7 1.1 1 0 0 1 1 1 1 BAR domain BAR_2 PF10455.9 KFX91869.1 - 0.00014 21.1 2.7 0.00018 20.8 2.7 1.1 1 0 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking PMEI PF04043.15 KFX91869.1 - 0.37 11.1 3.9 0.49 10.7 1.9 2.0 1 1 1 2 2 2 0 Plant invertase/pectin methylesterase inhibitor OmpH PF03938.14 KFX91869.1 - 0.64 10.3 9.8 0.53 10.6 7.3 1.9 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) GBP_C PF02841.14 KFX91869.1 - 6.7 6.0 13.0 0.4 10.0 7.1 1.7 2 0 0 2 2 2 0 Guanylate-binding protein, C-terminal domain NAD_binding_10 PF13460.6 KFX91874.1 - 9.8e-05 22.3 0.0 0.00014 21.8 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Polysacc_synt_2 PF02719.15 KFX91874.1 - 0.011 14.8 0.0 0.016 14.3 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Semialdhyde_dh PF01118.24 KFX91874.1 - 0.025 15.0 0.0 0.047 14.1 0.0 1.5 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain NAD_binding_4 PF07993.12 KFX91874.1 - 0.056 12.6 0.0 0.24 10.5 0.0 2.0 2 1 0 2 2 2 0 Male sterility protein KR PF08659.10 KFX91874.1 - 0.12 12.3 0.0 1.1 9.1 0.0 2.1 2 0 0 2 2 2 0 KR domain DapB_N PF01113.20 KFX91874.1 - 0.13 12.4 0.0 0.21 11.7 0.0 1.4 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Epimerase PF01370.21 KFX91874.1 - 0.2 11.1 0.0 0.26 10.7 0.0 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Sugar_tr PF00083.24 KFX91875.1 - 1.1e-80 271.7 16.9 1.4e-80 271.4 16.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KFX91875.1 - 3.2e-22 78.9 27.4 7.5e-22 77.7 25.6 2.2 1 1 2 3 3 3 2 Major Facilitator Superfamily MFS_1_like PF12832.7 KFX91875.1 - 1 8.2 13.6 0.064 12.1 3.5 2.3 2 0 0 2 2 2 0 MFS_1 like family zf-C2H2 PF00096.26 KFX91876.1 - 0.73 10.4 13.5 0.03 14.8 3.2 2.8 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-H2C2_5 PF13909.6 KFX91876.1 - 0.92 9.3 14.2 0.081 12.7 2.7 3.4 3 0 0 3 3 3 0 C2H2-type zinc-finger domain zf-C2H2_4 PF13894.6 KFX91876.1 - 2.1 9.4 17.3 0.73 10.8 2.6 4.2 3 0 0 3 3 3 0 C2H2-type zinc finger DUF4246 PF14033.6 KFX91877.1 - 4.8e-118 395.1 0.0 9.8e-102 341.4 0.0 2.0 2 0 0 2 2 2 2 Protein of unknown function (DUF4246) NAM-associated PF14303.6 KFX91878.1 - 0.093 13.4 0.6 0.096 13.4 0.6 1.1 1 0 0 1 1 1 0 No apical meristem-associated C-terminal domain DEAD PF00270.29 KFX91885.1 - 3.1e-37 128.0 0.0 7.5e-37 126.8 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KFX91885.1 - 2.6e-21 76.0 0.0 8e-21 74.5 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 KFX91885.1 - 4.9e-20 71.5 0.0 1e-19 70.5 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.15 KFX91885.1 - 0.0051 16.8 0.0 0.028 14.4 0.0 2.1 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 KFX91885.1 - 0.66 10.2 4.2 0.71 10.1 0.3 2.8 2 1 0 2 2 2 0 AAA domain DUF3492 PF11997.8 KFX91885.1 - 7.3 6.2 5.7 14 5.4 5.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3492) DUF3984 PF13136.6 KFX91886.1 - 0.074 12.4 2.6 0.11 11.8 2.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3984) KxDL PF10241.9 KFX91887.1 - 3e-28 97.9 2.2 4.4e-28 97.4 2.2 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein UPF0242 PF06785.11 KFX91887.1 - 0.081 13.0 1.0 0.1 12.7 1.0 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus DUF4164 PF13747.6 KFX91887.1 - 0.083 13.2 2.3 0.12 12.6 2.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4164) DUF883 PF05957.13 KFX91887.1 - 0.088 13.4 5.7 0.46 11.1 3.0 2.3 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) ATP-synt_DE PF00401.20 KFX91887.1 - 2.1 8.7 10.7 2 8.7 7.0 2.2 2 0 0 2 2 2 0 ATP synthase, Delta/Epsilon chain, long alpha-helix domain PBP1_TM PF14812.6 KFX91889.1 - 0.5 10.8 5.9 1.1 9.7 6.0 1.6 1 1 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal TT_ORF2 PF02957.15 KFX91889.1 - 2 9.3 6.3 0.25 12.3 0.7 2.1 3 0 0 3 3 3 0 TT viral ORF2 Ribosomal_L2_C PF03947.18 KFX91900.1 - 3.7e-41 140.3 4.8 6.2e-41 139.5 4.8 1.3 1 0 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.23 KFX91900.1 - 9.8e-15 54.3 0.1 2.3e-14 53.1 0.1 1.7 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain PfkB PF00294.24 KFX91901.1 - 3.9e-67 226.7 0.1 4.4e-67 226.5 0.1 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Phos_pyr_kin PF08543.12 KFX91901.1 - 0.052 12.9 0.0 0.13 11.6 0.0 1.6 2 0 0 2 2 2 0 Phosphomethylpyrimidine kinase EST1_DNA_bind PF10373.9 KFX91902.1 - 1.8e-54 185.1 0.0 3.4e-54 184.2 0.0 1.5 1 0 0 1 1 1 1 Est1 DNA/RNA binding domain EST1 PF10374.9 KFX91902.1 - 1.1e-20 74.6 1.5 3.1e-20 73.2 1.5 1.8 1 0 0 1 1 1 1 Telomerase activating protein Est1 zf-C2H2_jaz PF12171.8 KFX91903.1 - 0.048 14.0 1.7 0.29 11.5 0.3 2.5 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-C2H2 PF00096.26 KFX91903.1 - 0.4 11.2 14.5 0.6 10.7 1.3 3.5 3 0 0 3 3 3 0 Zinc finger, C2H2 type TB2_DP1_HVA22 PF03134.19 KFX91904.1 - 2.4e-28 97.9 6.5 2.4e-28 97.9 6.5 1.6 2 0 0 2 2 2 1 TB2/DP1, HVA22 family Bestrophin PF01062.21 KFX91904.1 - 0.092 12.1 2.2 0.11 11.8 2.2 1.2 1 0 0 1 1 1 0 Bestrophin, RFP-TM, chloride channel RFX_DNA_binding PF02257.15 KFX91905.1 - 1.3e-28 99.4 0.2 4.7e-28 97.6 0.1 2.1 2 0 0 2 2 2 1 RFX DNA-binding domain Mid1 PF12929.7 KFX91906.1 - 0.0021 17.4 0.0 0.0026 17.0 0.0 1.1 1 0 0 1 1 1 1 Stretch-activated Ca2+-permeable channel component Mid1 PF12929.7 KFX91907.1 - 2.6e-138 461.8 0.3 3e-138 461.6 0.3 1.0 1 0 0 1 1 1 1 Stretch-activated Ca2+-permeable channel component Fz PF01392.22 KFX91907.1 - 0.00039 21.0 4.0 0.021 15.4 0.7 2.5 2 1 0 2 2 2 2 Fz domain Fungal_trans PF04082.18 KFX91909.1 - 2.2e-06 26.9 0.1 3.5e-06 26.3 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain CaATP_NAI PF12515.8 KFX91909.1 - 0.064 12.9 0.0 0.21 11.2 0.0 1.9 1 0 0 1 1 1 0 Ca2+-ATPase N terminal autoinhibitory domain Glyco_hydro_2_N PF02837.18 KFX91910.1 - 2.6e-14 53.5 0.0 6.2e-14 52.3 0.0 1.6 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_2_C PF02836.17 KFX91910.1 - 1.6e-11 43.9 0.0 1.5e-10 40.7 0.0 2.3 1 1 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Glyco_hydro_2 PF00703.21 KFX91910.1 - 5.6e-11 43.1 0.1 4.4e-10 40.2 0.0 2.2 2 0 0 2 2 2 1 Glycosyl hydrolases family 2 BetaGal_dom4_5 PF13364.6 KFX91910.1 - 0.017 15.7 0.1 0.078 13.5 0.1 2.1 2 0 0 2 2 2 0 Beta-galactosidase jelly roll domain DJ-1_PfpI PF01965.24 KFX91911.1 - 6.1e-07 29.4 0.0 1e-06 28.7 0.0 1.4 1 1 0 1 1 1 1 DJ-1/PfpI family Mre11_DNA_bind PF04152.14 KFX91912.1 - 1.2e-52 178.7 0.3 2.2e-52 177.8 0.3 1.5 1 0 0 1 1 1 1 Mre11 DNA-binding presumed domain Metallophos PF00149.28 KFX91912.1 - 5.9e-15 56.3 1.7 2.9e-14 54.1 1.7 2.0 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 KFX91912.1 - 1.3e-05 25.4 0.1 0.00028 21.1 0.1 2.7 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Ribosomal_S19 PF00203.21 KFX91913.1 - 1.6e-27 95.2 0.2 1.8e-27 95.0 0.2 1.1 1 0 0 1 1 1 1 Ribosomal protein S19 SnoaL_2 PF12680.7 KFX91914.1 - 0.012 16.2 0.0 0.026 15.2 0.0 1.5 1 0 0 1 1 1 0 SnoaL-like domain Pkinase_C PF00433.24 KFX91914.1 - 0.078 13.7 1.0 27 5.6 0.1 3.1 2 0 0 2 2 2 0 Protein kinase C terminal domain Pkinase PF00069.25 KFX91918.1 - 2.8e-47 161.3 0.0 9.4e-47 159.6 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFX91918.1 - 8.2e-19 67.9 0.0 1.6e-18 67.0 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase FTA2 PF13095.6 KFX91918.1 - 0.00094 18.9 0.0 0.17 11.5 0.0 2.2 2 0 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 KFX91918.1 - 0.011 15.6 0.1 4.2 7.2 0.0 2.7 2 1 0 3 3 3 0 Phosphotransferase enzyme family Kdo PF06293.14 KFX91918.1 - 0.097 12.0 0.0 0.15 11.4 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 KFX91918.1 - 0.13 11.8 0.2 0.32 10.6 0.2 1.7 1 1 0 1 1 1 0 RIO1 family Cir_N PF10197.9 KFX91919.1 - 1.9e-05 24.7 1.5 1.9e-05 24.7 1.5 4.1 4 0 0 4 4 4 1 N-terminal domain of CBF1 interacting co-repressor CIR Rhomboid PF01694.22 KFX91921.1 - 1.4e-32 112.8 10.3 1.4e-32 112.8 10.3 1.6 2 0 0 2 2 2 1 Rhomboid family DUF4381 PF14316.6 KFX91921.1 - 1.6 9.0 4.9 3.6 7.8 4.9 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) DNA_pol_B PF00136.21 KFX91922.1 - 1.3e-148 495.5 2.1 1.9e-148 495.0 2.1 1.3 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.19 KFX91922.1 - 7e-78 262.1 0.2 1.4e-77 261.1 0.1 1.6 2 0 0 2 2 2 1 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.6 KFX91922.1 - 7.9e-18 64.7 7.1 1.9e-17 63.5 7.1 1.7 1 0 0 1 1 1 1 C4-type zinc-finger of DNA polymerase delta DNA_pol_B_exo2 PF10108.9 KFX91922.1 - 0.0018 18.0 0.1 0.0036 17.0 0.1 1.4 1 0 0 1 1 1 1 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB RNase_H_2 PF13482.6 KFX91922.1 - 0.0057 16.6 0.3 0.07 13.1 0.3 2.7 1 1 0 1 1 1 1 RNase_H superfamily DNA_pol_B_2 PF03175.13 KFX91922.1 - 0.033 13.1 0.1 1.2 7.9 0.0 2.3 2 0 0 2 2 2 0 DNA polymerase type B, organellar and viral C1_1 PF00130.22 KFX91922.1 - 0.36 10.7 10.2 0.54 10.2 1.0 2.5 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Acyl-CoA_dh_1 PF00441.24 KFX91924.1 - 9.8e-36 123.2 1.4 1.2e-35 123.0 0.1 1.8 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 KFX91924.1 - 3.6e-18 65.6 0.2 6.6e-18 64.7 0.2 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 KFX91924.1 - 4.2e-10 40.0 0.2 1.8e-09 38.0 0.0 2.1 2 1 1 3 3 3 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 KFX91924.1 - 4.5e-10 40.2 0.0 3e-09 37.6 0.0 2.5 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain CFEM PF05730.11 KFX91924.1 - 1.4e-07 31.5 6.5 3e-07 30.4 6.5 1.6 1 0 0 1 1 1 1 CFEM domain HpaB_N PF11794.8 KFX91924.1 - 0.0027 17.4 0.0 0.0052 16.5 0.0 1.4 1 0 0 1 1 1 1 4-hydroxyphenylacetate 3-hydroxylase N terminal adh_short PF00106.25 KFX91925.1 - 1.2e-05 24.8 0.0 0.00012 21.5 0.0 2.0 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 KFX91925.1 - 3.1e-05 23.7 0.0 5.9e-05 22.7 0.0 1.4 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase G-patch_2 PF12656.7 KFX91929.1 - 1.6e-17 63.3 0.3 1.6e-17 63.3 0.3 3.1 3 0 0 3 3 3 1 G-patch domain LapA_dom PF06305.11 KFX91930.1 - 0.021 14.6 0.1 0.034 14.0 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain Fcf1 PF04900.12 KFX91931.1 - 7.6e-37 125.7 0.1 1.2e-36 125.1 0.1 1.3 1 0 0 1 1 1 1 Fcf1 PIN_9 PF18477.1 KFX91931.1 - 1.6e-12 47.8 0.5 4.1e-12 46.4 0.1 1.8 2 0 0 2 2 2 1 PIN like domain ATP-synt_S1 PF05827.12 KFX91932.1 - 4.7e-06 26.5 0.1 9.2e-06 25.6 0.1 1.4 1 0 0 1 1 1 1 Vacuolar ATP synthase subunit S1 (ATP6S1) Nop25 PF09805.9 KFX91933.1 - 9.7e-38 129.7 13.1 9.7e-38 129.7 13.1 2.3 2 1 0 2 2 2 1 Nucleolar protein 12 (25kDa) Tropomyosin_1 PF12718.7 KFX91934.1 - 1.9e-51 174.0 34.2 2.2e-51 173.8 34.2 1.0 1 0 0 1 1 1 1 Tropomyosin like Tropomyosin PF00261.20 KFX91934.1 - 1.1e-09 38.0 31.7 2.3e-06 27.2 17.9 2.6 1 1 1 2 2 2 2 Tropomyosin ERM PF00769.19 KFX91934.1 - 0.0012 18.7 33.3 0.0059 16.5 11.1 2.0 1 1 1 2 2 2 2 Ezrin/radixin/moesin family Uso1_p115_C PF04871.13 KFX91934.1 - 0.0016 18.8 33.7 0.14 12.6 12.0 2.0 1 1 1 2 2 2 2 Uso1 / p115 like vesicle tethering protein, C terminal region Jnk-SapK_ap_N PF09744.9 KFX91934.1 - 0.0023 18.2 33.0 0.0042 17.3 20.6 2.1 1 1 1 2 2 2 1 JNK_SAPK-associated protein-1 GAS PF13851.6 KFX91934.1 - 0.0034 16.8 32.2 0.0066 15.8 32.2 1.5 1 1 0 1 1 1 1 Growth-arrest specific micro-tubule binding KLRAQ PF10205.9 KFX91934.1 - 0.0036 17.5 22.2 0.076 13.3 8.9 2.9 1 1 1 2 2 2 2 Predicted coiled-coil domain-containing protein KELK PF15796.5 KFX91934.1 - 0.0037 17.7 31.7 0.009 16.4 1.4 4.0 1 1 3 4 4 4 2 KELK-motif containing domain of MRCK Ser/Thr protein kinase Spc7 PF08317.11 KFX91934.1 - 0.0042 16.0 31.8 0.0045 15.9 18.3 2.0 1 1 1 2 2 2 1 Spc7 kinetochore protein HOOK PF05622.12 KFX91934.1 - 0.0048 15.1 28.1 0.0086 14.3 28.1 1.4 1 1 0 1 1 1 1 HOOK protein Cep57_CLD_2 PF14197.6 KFX91934.1 - 0.0055 16.8 30.1 0.52 10.4 1.9 4.1 2 2 0 3 3 3 2 Centrosome localisation domain of PPC89 DUF724 PF05266.14 KFX91934.1 - 0.01 15.7 22.8 0.1 12.4 6.4 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF724) HMMR_N PF15905.5 KFX91934.1 - 0.018 14.6 31.0 0.05 13.1 31.0 1.6 1 1 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal CENP-F_leu_zip PF10473.9 KFX91934.1 - 0.018 15.1 2.1 0.018 15.1 2.1 3.0 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 TMF_TATA_bd PF12325.8 KFX91934.1 - 0.02 15.1 25.1 0.24 11.6 18.0 2.3 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding DUF3450 PF11932.8 KFX91934.1 - 0.028 13.7 24.6 0.44 9.8 10.7 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) JAKMIP_CC3 PF16034.5 KFX91934.1 - 0.029 14.3 5.9 0.029 14.3 5.9 2.2 1 1 1 2 2 2 0 JAKMIP CC3 domain DUF3584 PF12128.8 KFX91934.1 - 0.037 11.6 23.9 0.043 11.3 23.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) FlaC_arch PF05377.11 KFX91934.1 - 0.039 14.3 19.6 0.67 10.4 1.8 4.2 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) Phage_DsbA PF11126.8 KFX91934.1 - 0.085 13.1 1.0 0.085 13.1 1.0 2.5 2 1 1 3 3 2 0 Transcriptional regulator DsbA Seryl_tRNA_N PF02403.22 KFX91934.1 - 0.11 12.7 27.3 2.5 8.3 5.5 3.1 1 1 2 3 3 3 0 Seryl-tRNA synthetase N-terminal domain Laminin_II PF06009.12 KFX91934.1 - 0.11 12.5 19.5 0.11 12.5 6.1 2.7 1 1 1 2 2 2 0 Laminin Domain II ATG16 PF08614.11 KFX91934.1 - 0.12 12.6 31.4 6.1 7.0 12.4 2.3 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) EzrA PF06160.12 KFX91934.1 - 0.13 10.4 24.8 0.089 10.9 5.0 1.9 1 1 1 2 2 2 0 Septation ring formation regulator, EzrA Sec34 PF04136.15 KFX91934.1 - 0.14 12.0 17.3 0.13 12.2 2.7 2.2 1 1 1 2 2 2 0 Sec34-like family DUF1664 PF07889.12 KFX91934.1 - 0.16 12.0 14.7 0.32 11.0 2.2 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) APG6_N PF17675.1 KFX91934.1 - 0.18 12.3 36.3 3.6 8.1 21.5 2.3 1 1 1 2 2 2 0 Apg6 coiled-coil region Cep57_MT_bd PF06657.13 KFX91934.1 - 0.2 12.1 20.6 0.45 11.0 0.3 3.6 1 1 2 3 3 3 0 Centrosome microtubule-binding domain of Cep57 DHR10 PF18595.1 KFX91934.1 - 0.21 11.7 32.1 1.5 8.9 4.5 2.9 1 1 1 2 2 2 0 Designed helical repeat protein 10 domain MAD PF05557.13 KFX91934.1 - 0.24 9.7 28.8 1.2 7.4 13.3 2.0 1 1 1 2 2 2 0 Mitotic checkpoint protein Fez1 PF06818.15 KFX91934.1 - 0.26 11.7 27.0 0.43 11.0 26.2 1.6 1 1 0 1 1 1 0 Fez1 ADIP PF11559.8 KFX91934.1 - 0.29 11.2 31.2 4.1 7.5 13.6 3.0 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding bZIP_2 PF07716.15 KFX91934.1 - 0.29 11.2 35.5 0.11 12.6 4.8 5.2 3 1 1 5 5 5 0 Basic region leucine zipper DUF4763 PF15960.5 KFX91934.1 - 0.35 10.2 17.7 1.4 8.2 3.9 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4763) BLOC1_2 PF10046.9 KFX91934.1 - 0.35 11.2 22.6 4.1 7.8 0.4 3.5 1 1 2 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Filament PF00038.21 KFX91934.1 - 0.36 10.4 27.4 0.68 9.5 27.4 1.4 1 1 0 1 1 1 0 Intermediate filament protein STAT_alpha PF01017.20 KFX91934.1 - 0.37 10.7 19.8 0.45 10.4 0.7 2.3 1 1 1 2 2 2 0 STAT protein, all-alpha domain Lebercilin PF15619.6 KFX91934.1 - 0.39 10.4 31.8 4.5 6.9 17.2 2.2 1 1 1 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease T3SSipB PF16535.5 KFX91934.1 - 0.44 11.0 17.1 4 7.9 7.3 2.6 1 1 1 2 2 2 0 Type III cell invasion protein SipB Taxilin PF09728.9 KFX91934.1 - 0.48 9.5 29.5 1.5 7.9 8.6 2.2 1 1 1 2 2 2 0 Myosin-like coiled-coil protein SOGA PF11365.8 KFX91934.1 - 0.54 11.4 24.2 3.3 8.9 8.0 3.8 1 1 2 3 3 3 0 Protein SOGA ZapB PF06005.12 KFX91934.1 - 0.63 10.5 38.5 68 4.0 21.9 4.0 1 1 2 3 3 3 0 Cell division protein ZapB TANGO2 PF05742.12 KFX91934.1 - 0.82 9.7 8.6 1.5 8.8 8.2 1.7 1 1 0 1 1 1 0 Transport and Golgi organisation 2 bZIP_1 PF00170.21 KFX91934.1 - 0.92 9.7 31.1 1.8 8.7 2.7 4.8 2 1 3 5 5 5 0 bZIP transcription factor DUF745 PF05335.13 KFX91934.1 - 0.92 9.2 20.4 0.14 11.9 1.8 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF745) DUF4200 PF13863.6 KFX91934.1 - 1.1 9.7 31.9 2.4 8.6 17.8 2.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) DUF4201 PF13870.6 KFX91934.1 - 1.3 8.8 28.8 18 5.0 28.8 2.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4201) BST2 PF16716.5 KFX91934.1 - 1.3 9.7 26.1 0.24 12.0 1.0 3.2 1 1 2 3 3 2 0 Bone marrow stromal antigen 2 HAP1_N PF04849.13 KFX91934.1 - 1.3 8.2 29.8 20 4.3 29.8 2.5 1 1 0 1 1 1 0 HAP1 N-terminal conserved region BRE1 PF08647.11 KFX91934.1 - 1.4 9.1 30.6 0.74 9.9 18.5 2.5 1 1 1 2 2 2 0 BRE1 E3 ubiquitin ligase CALCOCO1 PF07888.11 KFX91934.1 - 1.5 7.6 30.1 3.4 6.4 7.9 2.2 1 1 1 2 2 2 0 Calcium binding and coiled-coil domain (CALCOCO1) like Leu_zip PF15294.6 KFX91934.1 - 1.6 8.2 24.7 2.1 7.8 24.7 1.1 1 0 0 1 1 1 0 Leucine zipper USP8_interact PF08941.10 KFX91934.1 - 2.1 8.1 9.3 3.3 7.5 8.4 1.8 1 1 1 2 2 2 0 USP8 interacting YabA PF06156.13 KFX91934.1 - 2.2 9.0 26.4 19 6.0 7.5 3.1 1 1 2 3 3 3 0 Initiation control protein YabA NYD-SP28 PF14772.6 KFX91934.1 - 2.2 8.4 26.3 0.071 13.2 12.5 2.7 1 1 1 2 2 2 0 Sperm tail SlyX PF04102.12 KFX91934.1 - 2.3 8.9 19.2 1.8 9.2 5.9 3.3 1 1 3 4 4 4 0 SlyX TPR_MLP1_2 PF07926.12 KFX91934.1 - 2.3 8.3 35.3 17 5.5 26.9 2.9 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein Atg14 PF10186.9 KFX91934.1 - 2.5 7.1 22.9 1.4 7.9 14.6 2.0 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 LPP PF04728.13 KFX91934.1 - 3 8.3 12.6 96 3.5 5.4 4.1 3 1 0 3 3 3 0 Lipoprotein leucine-zipper SHE3 PF17078.5 KFX91934.1 - 3 7.5 26.6 4.9 6.8 1.0 2.0 1 1 0 1 1 1 0 SWI5-dependent HO expression protein 3 XhlA PF10779.9 KFX91934.1 - 3 8.1 28.4 0.6 10.4 3.3 4.0 1 1 3 4 4 4 0 Haemolysin XhlA DUF16 PF01519.16 KFX91934.1 - 3 8.4 22.4 14 6.3 2.4 3.0 1 1 1 2 2 1 0 Protein of unknown function DUF16 Exonuc_VII_L PF02601.15 KFX91934.1 - 3.3 7.2 15.7 4.7 6.7 15.7 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit Cortex-I_coil PF09304.10 KFX91934.1 - 3.4 7.9 22.8 3.5 7.9 7.4 2.9 1 1 2 3 3 3 0 Cortexillin I, coiled coil CENP-H PF05837.12 KFX91934.1 - 3.5 8.1 25.8 46 4.5 0.1 3.0 1 1 1 2 2 1 0 Centromere protein H (CENP-H) DUF4472 PF14739.6 KFX91934.1 - 3.5 8.4 27.3 1.8 9.3 9.0 3.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4472) TMF_DNA_bd PF12329.8 KFX91934.1 - 3.6 7.7 35.1 2.6 8.1 7.5 3.8 1 1 3 4 4 4 0 TATA element modulatory factor 1 DNA binding CASP_C PF08172.12 KFX91934.1 - 3.7 6.8 21.4 0.17 11.2 1.9 2.1 1 1 1 2 2 2 0 CASP C terminal FapA PF03961.13 KFX91934.1 - 4.6 5.7 25.7 0.75 8.3 7.2 2.0 1 1 1 2 2 2 0 Flagellar Assembly Protein A PI3K_P85_iSH2 PF16454.5 KFX91934.1 - 4.7 6.8 27.8 9.9 5.7 0.9 2.5 1 1 1 2 2 2 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain DUF4407 PF14362.6 KFX91934.1 - 5.5 6.3 22.7 31 3.8 22.7 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Prefoldin PF02996.17 KFX91934.1 - 5.7 6.9 28.3 2.4 8.1 4.7 4.0 1 1 3 4 4 4 0 Prefoldin subunit Lge1 PF11488.8 KFX91934.1 - 6.1 7.1 20.4 0.11 12.7 1.3 3.9 1 1 2 3 3 2 0 Transcriptional regulatory protein LGE1 FAP206 PF12018.8 KFX91934.1 - 6.6 6.2 14.1 0.26 10.7 5.6 2.0 1 1 1 2 2 2 0 Domain of unknown function KASH_CCD PF14662.6 KFX91934.1 - 6.9 6.5 31.3 3.7 7.3 20.3 2.2 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 or KASH Shugoshin_N PF07558.11 KFX91934.1 - 7.6 6.5 10.4 0.6 10.0 0.2 3.4 4 0 0 4 4 2 0 Shugoshin N-terminal coiled-coil region HemX PF04375.14 KFX91934.1 - 8.5 5.6 22.8 59 2.8 18.2 2.2 1 1 1 2 2 2 0 HemX, putative uroporphyrinogen-III C-methyltransferase Fmp27_WPPW PF10359.9 KFX91934.1 - 9 5.0 24.3 0.25 10.1 8.3 2.0 1 1 1 2 2 2 0 RNA pol II promoter Fmp27 protein domain AAA_13 PF13166.6 KFX91934.1 - 9.1 4.8 25.7 55 2.2 25.7 1.8 1 1 0 1 1 1 0 AAA domain Vps26 PF03643.15 KFX91940.1 - 5.2e-128 425.8 0.7 6.1e-128 425.6 0.7 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 26 Arrestin_N PF00339.29 KFX91940.1 - 0.00044 20.3 1.6 1.9 8.6 0.0 3.4 2 1 2 4 4 4 2 Arrestin (or S-antigen), N-terminal domain KilA-N PF04383.13 KFX91943.1 - 0.00041 20.2 0.0 0.0072 16.2 0.0 2.6 1 1 0 1 1 1 1 KilA-N domain Ric8 PF10165.9 KFX91951.1 - 4e-49 167.9 6.2 6.9e-47 160.5 6.2 2.0 1 1 0 1 1 1 1 Guanine nucleotide exchange factor synembryn FGF-BP1 PF06473.12 KFX91951.1 - 0.0065 16.3 4.2 0.0087 15.9 4.2 1.2 1 0 0 1 1 1 1 FGF binding protein 1 (FGF-BP1) NARP1 PF12569.8 KFX91951.1 - 0.014 14.3 7.6 0.021 13.8 7.6 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 GAGA_bind PF06217.12 KFX91951.1 - 0.033 14.5 2.3 0.044 14.1 2.3 1.2 1 0 0 1 1 1 0 GAGA binding protein-like family SpoVR PF04293.13 KFX91951.1 - 0.17 10.5 4.3 0.24 10.1 4.3 1.1 1 0 0 1 1 1 0 SpoVR like protein Presenilin PF01080.17 KFX91951.1 - 0.2 10.4 2.4 0.24 10.1 2.4 1.1 1 0 0 1 1 1 0 Presenilin RP-C_C PF11800.8 KFX91951.1 - 0.25 11.4 4.3 0.48 10.5 4.3 1.4 1 0 0 1 1 1 0 Replication protein C C-terminal region Tim54 PF11711.8 KFX91951.1 - 0.29 9.9 5.1 0.38 9.5 5.1 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 TMEM214 PF10151.9 KFX91951.1 - 0.37 9.2 6.2 0.48 8.8 6.2 1.1 1 0 0 1 1 1 0 TMEM214, C-terminal, caspase 4 activator Vfa1 PF08432.10 KFX91951.1 - 0.5 10.7 12.8 0.76 10.1 12.8 1.2 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 ALMT PF11744.8 KFX91951.1 - 1.2 7.9 4.4 1.5 7.5 4.4 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter O-antigen_lig PF13425.6 KFX91951.1 - 7.4 5.2 6.6 9.9 4.8 6.6 1.1 1 0 0 1 1 1 0 O-antigen ligase like membrane protein Med19 PF10278.9 KFX91951.1 - 7.5 6.4 15.5 48 3.8 14.8 2.1 2 0 0 2 2 2 0 Mediator of RNA pol II transcription subunit 19 DUF4246 PF14033.6 KFX91968.1 - 8.3e-21 74.6 0.3 8.3e-21 74.6 0.3 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF4246) Secretin_N_2 PF07655.13 KFX91988.1 - 2.1 8.9 14.1 0.52 10.9 10.4 1.8 2 0 0 2 2 2 0 Secretin N-terminal domain Ribosomal_S13 PF00416.22 KFX91989.1 - 1.7e-55 186.8 2.7 2e-55 186.6 2.7 1.0 1 0 0 1 1 1 1 Ribosomal protein S13/S18 FbpA PF05833.11 KFX91989.1 - 0.0074 15.1 0.0 0.019 13.8 0.0 1.4 1 1 1 2 2 2 1 Fibronectin-binding protein A N-terminus (FbpA) HHH_6 PF14579.6 KFX91989.1 - 0.039 14.2 0.1 0.2 11.9 0.0 2.1 1 1 1 2 2 2 0 Helix-hairpin-helix motif DUF2746 PF10874.8 KFX91989.1 - 0.04 14.3 0.0 0.059 13.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2746) SBDS_C PF09377.10 KFX91990.1 - 1.7e-42 144.1 0.3 2.9e-42 143.4 0.1 1.5 2 0 0 2 2 2 1 SBDS protein C-terminal domain SBDS PF01172.18 KFX91990.1 - 1.4e-34 118.0 1.0 3e-34 117.0 1.0 1.5 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein DUF627 PF04781.12 KFX91990.1 - 0.11 12.5 0.2 0.33 11.0 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF627) Peptidase_S10 PF00450.22 KFX91991.1 - 3.2e-128 428.7 0.9 3.9e-128 428.4 0.9 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase Carbpep_Y_N PF05388.11 KFX91991.1 - 1.7e-18 67.4 0.7 6.7e-18 65.4 0.7 2.0 1 1 0 1 1 1 1 Carboxypeptidase Y pro-peptide RNA_pol_Rpb2_6 PF00562.28 KFX91993.1 - 8.5e-89 298.3 0.0 2e-88 297.1 0.0 1.5 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 KFX91993.1 - 3.4e-53 180.2 0.1 5.1e-53 179.6 0.1 1.3 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.14 KFX91993.1 - 1.8e-29 102.7 0.0 7.5e-29 100.7 0.0 2.0 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_4 PF04566.13 KFX91993.1 - 2.6e-22 78.8 0.0 6.2e-22 77.7 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_3 PF04565.16 KFX91993.1 - 2.4e-19 69.3 0.0 4.8e-19 68.3 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_5 PF04567.17 KFX91993.1 - 2.5e-10 40.7 1.2 8.5e-10 39.1 1.2 2.0 1 1 0 1 1 1 1 RNA polymerase Rpb2, domain 5 Sugar_tr PF00083.24 KFX91994.1 - 2.1e-90 303.7 27.1 2.6e-90 303.5 27.1 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KFX91994.1 - 2e-14 53.3 47.5 9.3e-09 34.7 17.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Abhydrolase_6 PF12697.7 KFX91995.1 - 1.4e-18 68.3 0.0 1.6e-18 68.2 0.0 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Sua5_yciO_yrdC PF01300.18 KFX91996.1 - 1.1e-14 54.3 0.0 1.8e-14 53.6 0.0 1.3 1 1 0 1 1 1 1 Telomere recombination LysM PF01476.20 KFX91998.1 - 5.1e-20 71.3 0.2 0.0086 16.1 0.0 5.6 5 0 0 5 5 5 4 LysM domain Cornifin PF02389.15 KFX91998.1 - 8 6.7 12.4 3.5 7.8 0.6 3.4 3 0 0 3 3 3 0 Cornifin (SPRR) family Glyco_hydro_18 PF00704.28 KFX91999.1 - 1.2e-67 228.8 0.0 1.5e-67 228.6 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Chitin_bind_1 PF00187.19 KFX91999.1 - 3.6e-09 36.9 9.8 3.6e-09 36.9 9.8 3.2 2 1 0 2 2 2 1 Chitin recognition protein Astacin PF01400.24 KFX92000.1 - 9.5e-10 38.4 4.4 0.00083 19.0 0.3 3.3 3 0 0 3 3 3 2 Astacin (Peptidase family M12A) Reprolysin_2 PF13574.6 KFX92000.1 - 0.061 13.2 0.1 0.13 12.2 0.1 1.5 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Peptidase_M10 PF00413.24 KFX92000.1 - 0.84 9.5 5.6 0.67 9.8 0.4 2.7 2 1 1 3 3 3 0 Matrixin Mito_carr PF00153.27 KFX92001.1 - 1.2e-44 150.1 3.0 1.3e-14 53.8 0.2 3.5 2 1 1 3 3 3 3 Mitochondrial carrier protein Fungal_lectin_2 PF18647.1 KFX92001.1 - 7.3e-38 129.1 0.9 1.6e-37 128.0 0.9 1.6 1 0 0 1 1 1 1 Alpha-galactosyl-binding fungal lectin Lipase_GDSL_2 PF13472.6 KFX92001.1 - 4.8e-10 40.1 3.6 1.7e-09 38.3 2.6 2.4 2 1 0 2 2 2 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 KFX92001.1 - 5.6e-06 26.5 0.1 1.9e-05 24.7 0.0 2.0 2 1 0 2 2 2 1 GDSL-like Lipase/Acylhydrolase IpaB_EvcA PF03278.13 KFX92001.1 - 0.0029 17.3 0.8 0.39 10.4 0.1 2.9 2 1 1 3 3 3 1 IpaB/EvcA family MCR_alpha PF02249.17 KFX92001.1 - 0.11 12.9 0.8 13 6.2 0.2 2.7 2 0 0 2 2 2 0 Methyl-coenzyme M reductase alpha subunit, C-terminal domain UBA PF00627.31 KFX92002.1 - 0.00014 21.6 0.1 0.00025 20.9 0.1 1.4 1 0 0 1 1 1 1 UBA/TS-N domain Methyltransf_25 PF13649.6 KFX92015.1 - 1.6e-11 44.8 0.0 4.5e-11 43.3 0.0 1.8 2 0 0 2 2 1 1 Methyltransferase domain PrmA PF06325.13 KFX92015.1 - 2.9e-11 43.3 0.0 4.3e-11 42.8 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_31 PF13847.6 KFX92015.1 - 1.6e-10 41.0 0.0 2.9e-10 40.1 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KFX92015.1 - 3.6e-08 33.9 0.0 1.3e-07 32.1 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 KFX92015.1 - 7.4e-07 29.1 0.0 1.7e-06 28.0 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_9 PF08003.11 KFX92015.1 - 1.3e-06 27.6 0.1 2e-06 27.0 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) CMAS PF02353.20 KFX92015.1 - 2.4e-05 23.8 0.1 3.7e-05 23.2 0.1 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_18 PF12847.7 KFX92015.1 - 3.1e-05 24.0 0.2 5.2e-05 23.2 0.2 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KFX92015.1 - 3.6e-05 23.4 0.1 7.1e-05 22.4 0.1 1.5 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_12 PF08242.12 KFX92015.1 - 0.00012 22.8 0.0 0.00024 21.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.18 KFX92015.1 - 0.0006 19.2 0.1 0.0011 18.3 0.1 1.4 1 0 0 1 1 1 1 O-methyltransferase domain Methyltransf_16 PF10294.9 KFX92015.1 - 0.0015 18.3 0.1 0.0022 17.8 0.1 1.2 1 0 0 1 1 1 1 Lysine methyltransferase FtsJ PF01728.19 KFX92015.1 - 0.0016 18.6 0.0 0.0029 17.7 0.0 1.4 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_32 PF13679.6 KFX92015.1 - 0.003 17.6 0.2 0.02 14.9 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain PCMT PF01135.19 KFX92015.1 - 0.0098 15.7 0.1 0.016 15.0 0.1 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) DOT1 PF08123.13 KFX92015.1 - 0.021 14.4 0.1 0.033 13.7 0.1 1.3 1 0 0 1 1 1 0 Histone methylation protein DOT1 TehB PF03848.14 KFX92015.1 - 0.034 13.6 0.1 0.06 12.8 0.1 1.4 1 0 0 1 1 1 0 Tellurite resistance protein TehB RrnaAD PF00398.20 KFX92015.1 - 0.066 12.3 0.0 0.12 11.4 0.0 1.4 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase PRMT5_C PF17286.2 KFX92015.1 - 0.077 12.9 0.0 0.12 12.3 0.0 1.3 1 0 0 1 1 1 0 PRMT5 oligomerisation domain Met_10 PF02475.16 KFX92015.1 - 0.093 12.5 0.1 0.21 11.3 0.1 1.6 1 0 0 1 1 1 0 Met-10+ like-protein PRMT5 PF05185.16 KFX92015.1 - 0.097 12.5 0.7 0.2 11.5 0.2 1.8 2 1 0 2 2 2 0 PRMT5 arginine-N-methyltransferase Methyltransf_24 PF13578.6 KFX92015.1 - 0.11 13.6 0.0 0.2 12.7 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Cons_hypoth95 PF03602.15 KFX92015.1 - 0.16 11.6 0.0 0.25 11.0 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical protein 95 Per1 PF04080.13 KFX92016.1 - 1.3e-103 346.3 8.3 1.5e-103 346.0 8.3 1.0 1 0 0 1 1 1 1 Per1-like family DEAD PF00270.29 KFX92017.1 - 5.6e-45 153.2 0.0 8.1e-45 152.7 0.0 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KFX92017.1 - 1.9e-30 105.4 0.0 1.4e-29 102.7 0.0 2.3 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 KFX92017.1 - 0.00037 20.5 0.0 0.00074 19.6 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Brix PF04427.18 KFX92018.1 - 2.1e-51 174.8 0.0 2.8e-51 174.4 0.0 1.2 1 0 0 1 1 1 1 Brix domain MRNIP PF15749.5 KFX92018.1 - 0.19 12.5 9.7 0.52 11.1 9.7 1.7 1 0 0 1 1 1 0 MRN-interacting protein AP3D1 PF06375.11 KFX92018.1 - 1 9.6 16.0 0.43 10.8 12.9 2.0 2 0 0 2 2 2 0 AP-3 complex subunit delta-1 PBP_sp32 PF07222.12 KFX92018.1 - 2.2 7.7 8.1 11 5.3 8.1 2.1 2 0 0 2 2 2 0 Proacrosin binding protein sp32 PPL5 PF18168.1 KFX92018.1 - 3 7.0 7.1 6.6 5.9 7.1 1.5 1 0 0 1 1 1 0 Prim-pol family 5 D-ser_dehydrat PF14031.6 KFX92028.1 - 1.8e-06 28.5 0.0 3.8e-06 27.5 0.0 1.5 1 0 0 1 1 1 1 Putative serine dehydratase domain Hamartin PF04388.12 KFX92029.1 - 5.1 5.6 6.9 6.5 5.3 6.9 1.1 1 0 0 1 1 1 0 Hamartin protein DUF755 PF05501.11 KFX92029.1 - 8.4 6.7 10.7 23 5.3 10.7 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF755) Laminin_II PF06009.12 KFX92031.1 - 1.6 8.8 9.6 1.4 8.9 7.2 2.0 1 1 1 2 2 2 0 Laminin Domain II TPR_MLP1_2 PF07926.12 KFX92031.1 - 3.2 7.8 20.5 0.96 9.5 16.3 2.3 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein Fez1 PF06818.15 KFX92031.1 - 4.2 7.8 27.3 0.089 13.2 14.0 2.3 1 1 1 2 2 2 0 Fez1 Lebercilin PF15619.6 KFX92031.1 - 8 6.1 29.2 6.6 6.3 12.8 3.1 1 1 2 3 3 3 0 Ciliary protein causing Leber congenital amaurosis disease MLANA PF14991.6 KFX92033.1 - 0.02 15.2 0.1 0.056 13.7 0.0 1.7 2 0 0 2 2 2 0 Protein melan-A Glyco_hydro_18 PF00704.28 KFX92035.1 - 1.7e-18 67.4 0.3 6.8e-18 65.4 0.3 1.7 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 Vps62 PF06101.11 KFX92036.1 - 0.00017 20.0 0.0 0.00028 19.3 0.0 1.2 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 62 GFO_IDH_MocA PF01408.22 KFX92040.1 - 1.5e-16 61.3 0.4 3.1e-16 60.3 0.4 1.5 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold NAD_binding_3 PF03447.16 KFX92040.1 - 0.016 15.8 0.2 0.027 15.1 0.2 1.4 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain F420_oxidored PF03807.17 KFX92040.1 - 0.12 12.9 0.1 0.28 11.8 0.1 1.6 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Ank_4 PF13637.6 KFX92043.1 - 2e-30 104.8 4.7 3.4e-05 24.3 0.0 8.1 6 2 2 8 8 8 6 Ankyrin repeats (many copies) Ank_2 PF12796.7 KFX92043.1 - 5.6e-25 87.7 1.2 7.7e-08 32.8 0.0 6.1 4 2 3 7 7 7 6 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KFX92043.1 - 1.6e-20 70.9 6.3 0.15 12.7 0.2 9.8 10 1 0 10 10 10 6 Ankyrin repeat Ank_5 PF13857.6 KFX92043.1 - 5.2e-20 71.3 10.8 0.00085 19.6 0.3 8.0 6 2 2 8 8 8 5 Ankyrin repeats (many copies) Ank PF00023.30 KFX92043.1 - 8.1e-20 70.3 5.0 0.0023 18.3 0.0 9.8 10 0 0 10 10 10 6 Ankyrin repeat Ada_Zn_binding PF02805.16 KFX92044.1 - 2e-29 101.4 3.2 3.9e-29 100.5 3.2 1.5 1 0 0 1 1 1 1 Metal binding domain of Ada HTH_AraC PF00165.23 KFX92044.1 - 2.1e-07 30.8 0.1 1.8e-06 27.9 0.0 2.2 2 0 0 2 2 2 1 Bacterial regulatory helix-turn-helix proteins, AraC family HTH_18 PF12833.7 KFX92044.1 - 0.0024 18.1 0.0 0.0054 17.0 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain Dak2 PF02734.17 KFX92045.1 - 1.2e-45 155.6 4.1 1.4e-45 155.4 4.1 1.0 1 0 0 1 1 1 1 DAK2 domain LSM PF01423.22 KFX92046.1 - 1.7e-18 66.0 0.0 2.2e-18 65.7 0.0 1.1 1 0 0 1 1 1 1 LSM domain ECH_2 PF16113.5 KFX92047.1 - 1.2e-125 419.5 0.0 2.1e-125 418.7 0.0 1.4 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_1 PF00378.20 KFX92047.1 - 1.4e-22 80.3 0.1 4.2e-22 78.7 0.0 1.7 2 0 0 2 2 2 1 Enoyl-CoA hydratase/isomerase K_channel_TID PF07941.11 KFX92047.1 - 0.051 14.0 5.8 0.24 11.9 5.8 2.2 1 0 0 1 1 1 0 Potassium channel Kv1.4 tandem inactivation domain DUF3591 PF12157.8 KFX92050.1 - 3.5e-184 612.6 1.5 4.5e-184 612.2 1.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3591) zf-CCHC PF00098.23 KFX92050.1 - 0.013 15.6 0.9 0.022 14.8 0.9 1.4 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_6 PF15288.6 KFX92050.1 - 0.022 14.6 2.4 0.051 13.4 2.4 1.6 1 0 0 1 1 1 0 Zinc knuckle TadE PF07811.12 KFX92051.1 - 0.16 12.2 0.7 0.36 11.2 0.7 1.5 1 0 0 1 1 1 0 TadE-like protein SAPS PF04499.15 KFX92052.1 - 1 8.1 6.0 1.7 7.4 6.0 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein ELO PF01151.18 KFX92054.1 - 1.6e-79 267.0 9.3 1.9e-79 266.8 9.3 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family MIF PF01187.18 KFX92055.1 - 7.8e-05 22.9 0.0 0.00013 22.2 0.0 1.3 1 0 0 1 1 1 1 Macrophage migration inhibitory factor (MIF) DUF3211 PF11485.8 KFX92055.1 - 1.7 8.9 5.7 0.52 10.5 0.2 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3211) TarH PF02203.15 KFX92056.1 - 0.88 9.5 4.4 0.65 9.9 0.6 2.1 2 0 0 2 2 2 0 Tar ligand binding domain homologue B12D PF06522.11 KFX92056.1 - 1.1 9.1 2.4 5.5 6.9 1.1 2.4 2 0 0 2 2 2 0 NADH-ubiquinone reductase complex 1 MLRQ subunit L6_membrane PF05805.12 KFX92056.1 - 1.4 8.5 6.8 0.79 9.3 4.7 1.7 2 1 0 2 2 2 0 L6 membrane protein GMC_oxred_N PF00732.19 KFX92057.1 - 2.2e-62 211.1 0.0 2.9e-62 210.7 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KFX92057.1 - 1.3e-32 113.3 0.0 2.3e-32 112.5 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 KFX92057.1 - 1.7e-06 27.4 1.4 0.0067 15.5 0.9 2.2 2 0 0 2 2 2 2 FAD binding domain Lycopene_cycl PF05834.12 KFX92057.1 - 0.0001 21.5 0.7 0.00019 20.6 0.7 1.4 1 0 0 1 1 1 1 Lycopene cyclase protein Thi4 PF01946.17 KFX92057.1 - 0.00011 21.6 0.2 0.017 14.4 0.1 2.3 2 0 0 2 2 2 2 Thi4 family NAD_binding_8 PF13450.6 KFX92057.1 - 0.00015 21.9 0.5 0.00041 20.5 0.5 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KFX92057.1 - 0.005 16.1 0.4 0.022 14.0 0.1 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KFX92057.1 - 0.0062 16.2 3.0 0.054 13.1 1.4 2.4 2 0 0 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.14 KFX92057.1 - 0.032 12.9 0.6 0.062 12.0 0.6 1.4 1 0 0 1 1 1 0 HI0933-like protein Pyr_redox_3 PF13738.6 KFX92057.1 - 0.12 11.6 1.2 0.55 9.4 0.8 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 KFX92057.1 - 0.22 10.3 0.4 0.36 9.6 0.4 1.3 1 0 0 1 1 1 0 Tryptophan halogenase Pyr_redox PF00070.27 KFX92057.1 - 0.5 11.0 2.2 1.8 9.2 0.7 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Beta-lactamase PF00144.24 KFX92058.1 - 1.2e-14 54.3 0.0 1.5e-14 54.0 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase Peptidase_S11 PF00768.20 KFX92058.1 - 0.2 11.1 0.0 0.3 10.5 0.0 1.2 1 0 0 1 1 1 0 D-alanyl-D-alanine carboxypeptidase Hce2 PF14856.6 KFX92067.1 - 2.3e-16 59.9 0.0 3.4e-16 59.4 0.0 1.3 1 0 0 1 1 1 1 Pathogen effector; putative necrosis-inducing factor GST_N_3 PF13417.6 KFX92068.1 - 1.6e-09 38.1 0.1 2.9e-09 37.2 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KFX92068.1 - 1.2e-08 35.1 0.0 2.7e-08 34.0 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 KFX92068.1 - 3e-07 30.6 0.0 5.9e-07 29.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 KFX92068.1 - 5.5e-07 29.7 0.0 1.2e-06 28.6 0.0 1.5 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 KFX92068.1 - 0.00039 20.7 0.0 0.00082 19.7 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KFX92068.1 - 0.00083 19.3 0.0 0.0018 18.3 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Pec_lyase_C PF00544.19 KFX92069.1 - 1.6e-42 145.5 10.5 2.1e-42 145.1 10.5 1.2 1 0 0 1 1 1 1 Pectate lyase SH3_3 PF08239.11 KFX92070.1 - 0.0027 18.0 0.0 0.0046 17.2 0.0 1.5 1 0 0 1 1 1 1 Bacterial SH3 domain DUF1992 PF09350.10 KFX92071.1 - 1.6e-14 53.8 0.3 4.9e-13 49.0 0.3 2.8 1 1 0 1 1 1 1 Domain of unknown function (DUF1992) RPAP1_N PF08621.10 KFX92071.1 - 0.087 12.6 0.0 0.2 11.4 0.0 1.6 1 0 0 1 1 1 0 RPAP1-like, N-terminal GHMP_kinases_N PF00288.26 KFX92072.1 - 2.6 8.4 5.7 3.2 8.1 0.2 2.4 2 0 0 2 2 2 0 GHMP kinases N terminal domain Pet191_N PF10203.9 KFX92072.1 - 4.5 7.6 6.8 17 5.8 0.1 3.4 3 0 0 3 3 3 0 Cytochrome c oxidase assembly protein PET191 Inhibitor_I78 PF11720.8 KFX92073.1 - 1.7e-06 28.0 0.2 0.0011 19.0 0.0 2.8 1 1 2 3 3 3 2 Peptidase inhibitor I78 family potato_inhibit PF00280.18 KFX92073.1 - 0.0051 17.5 0.0 0.018 15.7 0.0 1.9 2 0 0 2 2 2 1 Potato inhibitor I family FTP PF07504.13 KFX92073.1 - 0.15 12.0 0.1 0.27 11.1 0.1 1.4 1 0 0 1 1 1 0 Fungalysin/Thermolysin Propeptide Motif Pre-PUA PF17832.1 KFX92074.1 - 7.5e-25 87.4 0.4 9.8e-25 87.1 0.4 1.1 1 0 0 1 1 1 1 Pre-PUA-like domain PUA PF01472.20 KFX92074.1 - 1.7e-13 50.3 0.3 6e-13 48.6 0.3 1.8 1 1 0 1 1 1 1 PUA domain DUF1947 PF09183.10 KFX92074.1 - 0.0073 16.6 0.0 0.012 15.9 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1947) TFIID-31kDa PF02291.15 KFX92075.1 - 5.8e-44 149.1 0.0 7.7e-44 148.7 0.0 1.2 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit Histidinol_dh PF00815.20 KFX92076.1 - 1.6e-158 528.0 4.3 2.7e-158 527.3 4.3 1.4 1 0 0 1 1 1 1 Histidinol dehydrogenase PRA-CH PF01502.18 KFX92076.1 - 1.9e-23 82.1 0.1 3.8e-23 81.1 0.1 1.5 1 0 0 1 1 1 1 Phosphoribosyl-AMP cyclohydrolase SGTA_dimer PF16546.5 KFX92076.1 - 5.2e-22 77.4 1.7 7.7e-22 76.9 0.3 2.2 2 0 0 2 2 2 1 Homodimerisation domain of SGTA PRA-PH PF01503.17 KFX92076.1 - 1.2e-13 51.2 0.5 3.4e-13 49.8 0.5 1.8 1 0 0 1 1 1 1 Phosphoribosyl-ATP pyrophosphohydrolase TPR_2 PF07719.17 KFX92076.1 - 1.1e-11 43.9 2.4 0.00027 20.8 0.0 3.9 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.28 KFX92076.1 - 1.1e-10 40.9 0.5 0.0012 18.5 0.0 3.9 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 KFX92076.1 - 1.3e-06 28.9 9.2 1.5e-05 25.6 2.3 3.3 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 KFX92076.1 - 1.1e-05 25.2 1.8 0.089 13.1 0.1 4.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.6 KFX92076.1 - 2.1e-05 24.1 2.4 0.003 17.2 0.0 3.4 3 0 0 3 3 3 1 TPR repeat TPR_14 PF13428.6 KFX92076.1 - 0.00023 21.7 3.8 1.3 10.1 1.2 3.9 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_19 PF14559.6 KFX92076.1 - 0.0013 19.2 1.3 0.022 15.3 0.5 2.7 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_17 PF13431.6 KFX92076.1 - 0.0015 18.7 0.1 0.63 10.6 0.0 3.0 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.6 KFX92076.1 - 0.006 16.5 0.0 2.2 8.5 0.0 3.0 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.6 KFX92076.1 - 0.0083 16.4 1.0 0.08 13.2 0.3 2.8 1 1 1 2 2 2 1 Tetratricopeptide repeat STI1 PF17830.1 KFX92076.1 - 0.011 15.6 11.4 0.047 13.6 7.9 2.5 2 0 0 2 2 2 0 STI1 domain BTAD PF03704.17 KFX92076.1 - 0.12 12.8 0.7 18 5.7 0.0 2.5 1 1 1 2 2 2 0 Bacterial transcriptional activator domain MazG PF03819.17 KFX92076.1 - 0.25 11.5 2.4 0.33 11.1 0.9 1.9 2 0 0 2 2 2 0 MazG nucleotide pyrophosphohydrolase domain XPC-binding PF09280.11 KFX92076.1 - 0.48 10.2 4.1 0.38 10.5 2.2 1.8 2 0 0 2 2 2 0 XPC-binding domain ABC_tran PF00005.27 KFX92077.1 - 6.9e-34 117.3 0.0 1.7e-33 116.0 0.0 1.7 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.23 KFX92077.1 - 5.4e-25 88.6 1.8 1e-24 87.6 1.8 1.4 1 0 0 1 1 1 1 ABC transporter transmembrane region SMC_N PF02463.19 KFX92077.1 - 1.4e-06 27.9 0.0 0.00014 21.4 0.0 2.4 1 1 1 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_15 PF13175.6 KFX92077.1 - 0.00026 20.8 0.1 0.00043 20.1 0.1 1.3 1 0 0 1 1 1 1 AAA ATPase domain AAA_16 PF13191.6 KFX92077.1 - 0.00061 20.2 0.0 0.0014 19.0 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain AAA_21 PF13304.6 KFX92077.1 - 0.0025 17.7 0.3 0.0065 16.3 0.1 1.7 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 KFX92077.1 - 0.0031 17.8 0.2 0.022 15.0 0.2 2.3 1 1 0 1 1 1 1 AAA domain AAA_24 PF13479.6 KFX92077.1 - 0.0041 16.9 0.0 0.0096 15.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain DEAD PF00270.29 KFX92077.1 - 0.0047 16.7 0.0 0.013 15.2 0.0 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_30 PF13604.6 KFX92077.1 - 0.0047 16.7 0.4 0.1 12.3 0.1 2.7 2 1 0 2 2 2 1 AAA domain Zeta_toxin PF06414.12 KFX92077.1 - 0.0057 15.9 0.0 0.017 14.4 0.0 1.7 1 0 0 1 1 1 1 Zeta toxin AAA_29 PF13555.6 KFX92077.1 - 0.0079 15.9 0.2 0.024 14.3 0.2 1.8 1 0 0 1 1 1 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 KFX92077.1 - 0.008 16.1 0.0 0.021 14.7 0.0 1.6 1 0 0 1 1 1 1 RsgA GTPase AAA_23 PF13476.6 KFX92077.1 - 0.011 16.2 0.0 0.037 14.5 0.0 1.8 1 0 0 1 1 1 0 AAA domain G-alpha PF00503.20 KFX92077.1 - 0.028 13.6 0.0 0.047 12.9 0.0 1.3 1 0 0 1 1 1 0 G-protein alpha subunit AAA_5 PF07728.14 KFX92077.1 - 0.028 14.4 0.0 3.8 7.5 0.0 2.5 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_18 PF13238.6 KFX92077.1 - 0.17 12.4 0.6 1.2 9.7 0.0 2.7 3 0 0 3 3 3 0 AAA domain YchF-GTPase_C PF06071.13 KFX92078.1 - 1e-35 121.8 0.1 1.1e-35 121.6 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF933) TGS PF02824.21 KFX92078.1 - 5.6e-05 23.1 0.1 7.4e-05 22.7 0.1 1.2 1 0 0 1 1 1 1 TGS domain GFA PF04828.14 KFX92079.1 - 1.6e-18 66.8 4.7 2.8e-09 37.2 0.1 2.4 2 0 0 2 2 2 2 Glutathione-dependent formaldehyde-activating enzyme Transpos_assoc PF13963.6 KFX92079.1 - 0.58 10.5 4.1 4.4 7.7 0.4 2.6 2 0 0 2 2 2 0 Transposase-associated domain NOB1_Zn_bind PF08772.11 KFX92079.1 - 6.1 7.1 0.0 6.1 7.1 0.0 3.6 3 1 0 3 3 3 0 Nin one binding (NOB1) Zn-ribbon like TPR_10 PF13374.6 KFX92080.1 - 4.6e-98 318.8 7.3 3e-13 49.2 0.0 7.8 7 0 0 7 7 7 7 Tetratricopeptide repeat TPR_12 PF13424.6 KFX92080.1 - 9.3e-90 295.0 26.4 3.7e-19 68.8 0.3 6.9 1 1 5 7 7 7 7 Tetratricopeptide repeat TPR_1 PF00515.28 KFX92080.1 - 8e-29 98.3 22.2 0.00011 21.9 0.1 7.9 7 0 0 7 7 7 7 Tetratricopeptide repeat TPR_7 PF13176.6 KFX92080.1 - 8.9e-28 94.3 10.9 0.0019 18.1 0.1 7.8 7 0 0 7 7 7 6 Tetratricopeptide repeat TPR_8 PF13181.6 KFX92080.1 - 2.4e-25 86.6 13.2 0.00042 20.3 0.1 7.9 7 0 0 7 7 7 6 Tetratricopeptide repeat TPR_2 PF07719.17 KFX92080.1 - 1.2e-22 78.1 26.1 0.00094 19.1 0.1 8.5 9 0 0 9 9 7 7 Tetratricopeptide repeat Patatin PF01734.22 KFX92080.1 - 2.2e-19 70.5 0.0 4.3e-19 69.5 0.0 1.6 1 0 0 1 1 1 1 Patatin-like phospholipase TPR_MalT PF17874.1 KFX92080.1 - 3.1e-16 59.7 10.6 9.9e-08 31.7 4.8 3.6 1 1 2 3 3 3 3 MalT-like TPR region TPR_16 PF13432.6 KFX92080.1 - 1.6e-15 57.4 12.3 0.0015 19.1 0.1 6.4 4 2 2 6 6 5 4 Tetratricopeptide repeat TPR_14 PF13428.6 KFX92080.1 - 4.7e-11 42.5 13.7 0.27 12.1 0.0 8.2 8 0 0 8 8 7 2 Tetratricopeptide repeat TPR_3 PF07720.12 KFX92080.1 - 3.9e-10 39.5 17.5 0.045 13.7 0.1 8.3 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_17 PF13431.6 KFX92080.1 - 3.6e-09 36.4 4.5 3.2 8.3 0.0 6.8 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_4 PF07721.14 KFX92080.1 - 7.5e-09 35.4 2.5 23 6.0 0.0 8.0 8 0 0 8 8 7 0 Tetratricopeptide repeat PPR PF01535.20 KFX92080.1 - 1e-08 34.8 0.9 7.9 7.0 0.0 7.3 7 0 0 7 7 7 0 PPR repeat ANAPC3 PF12895.7 KFX92080.1 - 2.9e-05 24.2 8.6 2 8.7 0.3 6.8 2 1 6 8 8 8 1 Anaphase-promoting complex, cyclosome, subunit 3 Lge1 PF11488.8 KFX92080.1 - 0.00044 20.4 8.5 7.1 6.9 0.0 6.1 6 0 0 6 6 6 1 Transcriptional regulatory protein LGE1 TPR_19 PF14559.6 KFX92080.1 - 0.00052 20.5 21.0 0.089 13.3 0.4 6.3 3 2 3 6 6 6 2 Tetratricopeptide repeat NB-ARC PF00931.22 KFX92080.1 - 0.0077 15.4 0.0 0.021 14.0 0.0 1.7 1 0 0 1 1 1 1 NB-ARC domain kleA_kleC PF17383.2 KFX92080.1 - 0.0081 16.5 9.1 19 5.7 0.1 5.4 5 0 0 5 5 5 0 Uncharacterized KorC regulated protein A MIT PF04212.18 KFX92080.1 - 0.012 15.6 17.5 5.5 7.1 0.3 7.2 6 2 2 8 8 8 0 MIT (microtubule interacting and transport) domain DEP PF00610.21 KFX92080.1 - 0.082 13.0 0.0 0.4 10.8 0.0 2.2 1 0 0 1 1 1 0 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) TPR_11 PF13414.6 KFX92080.1 - 0.52 10.0 33.1 0.067 12.9 0.7 7.6 8 0 0 8 8 8 0 TPR repeat TPR_6 PF13174.6 KFX92080.1 - 4.9 8.0 18.0 19 6.2 0.2 6.8 7 1 0 7 7 5 0 Tetratricopeptide repeat 4HB_MCP_1 PF12729.7 KFX92080.1 - 6.5 6.3 12.5 27 4.2 0.0 5.7 6 1 0 7 7 7 0 Four helix bundle sensory module for signal transduction AdoMet_dc PF02675.15 KFX92081.1 - 0.19 12.0 0.2 0.25 11.6 0.2 1.2 1 0 0 1 1 1 0 S-adenosylmethionine decarboxylase IATP PF04568.12 KFX92081.1 - 2.7 8.5 3.4 3.8 8.0 3.4 1.2 1 0 0 1 1 1 0 Mitochondrial ATPase inhibitor, IATP Ferritin_2 PF13668.6 KFX92082.1 - 7.8e-43 145.9 3.7 7.8e-43 145.9 3.7 1.5 2 0 0 2 2 2 1 Ferritin-like domain MFS_1 PF07690.16 KFX92084.1 - 7.5e-16 58.0 37.9 2.8e-09 36.4 4.8 2.2 2 0 0 2 2 2 2 Major Facilitator Superfamily MOR2-PAG1_N PF14222.6 KFX92094.1 - 1.2e-224 747.4 0.1 3e-224 746.1 0.0 1.7 2 0 0 2 2 2 1 Cell morphogenesis N-terminal MOR2-PAG1_C PF14225.6 KFX92094.1 - 2.5e-91 306.1 0.5 7.3e-91 304.5 0.1 2.1 2 0 0 2 2 2 1 Cell morphogenesis C-terminal MOR2-PAG1_mid PF14228.6 KFX92094.1 - 7.7e-35 119.9 8.4 1.5e-12 46.1 0.1 3.8 2 1 2 4 4 4 3 Cell morphogenesis central region HEAT_2 PF13646.6 KFX92094.1 - 0.0047 17.3 1.2 0.19 12.1 0.0 4.3 4 0 0 4 4 4 1 HEAT repeats HEAT PF02985.22 KFX92094.1 - 0.026 14.8 0.1 5.7 7.5 0.0 4.1 3 0 0 3 3 3 0 HEAT repeat Cortex-I_coil PF09304.10 KFX92094.1 - 0.047 13.9 0.4 0.26 11.5 0.4 2.3 1 0 0 1 1 1 0 Cortexillin I, coiled coil HEAT_EZ PF13513.6 KFX92094.1 - 0.95 10.0 3.6 31 5.2 0.0 4.7 5 0 0 5 5 5 0 HEAT-like repeat Cid2 PF09774.9 KFX92103.1 - 7.3e-13 49.2 0.1 1e-12 48.8 0.1 1.2 1 0 0 1 1 1 1 Caffeine-induced death protein 2 Mito_carr PF00153.27 KFX92104.1 - 9.8e-46 153.6 0.7 4.8e-20 71.3 0.0 3.4 3 0 0 3 3 3 3 Mitochondrial carrier protein JAB PF01398.21 KFX92106.1 - 7.2e-09 35.6 0.7 1e-07 31.9 0.7 2.2 1 1 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease AdoHcyase PF05221.17 KFX92107.1 - 5.2e-130 433.0 0.0 7.3e-74 248.6 0.1 2.0 1 1 1 2 2 2 2 S-adenosyl-L-homocysteine hydrolase AdoHcyase_NAD PF00670.21 KFX92107.1 - 2.2e-82 274.9 3.2 3.3e-82 274.4 3.2 1.3 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 2-Hacid_dh_C PF02826.19 KFX92107.1 - 2.5e-07 30.2 0.1 5.4e-07 29.1 0.1 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ELFV_dehydrog PF00208.21 KFX92107.1 - 0.0012 18.7 0.8 0.0041 16.9 0.5 1.9 1 1 1 2 2 2 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase IlvN PF07991.12 KFX92107.1 - 0.0017 17.9 0.4 0.0033 17.0 0.4 1.4 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain TMEM107 PF14995.6 KFX92107.1 - 0.064 13.7 0.0 0.12 12.8 0.0 1.4 1 0 0 1 1 1 0 Transmembrane protein 3HCDH_N PF02737.18 KFX92107.1 - 0.08 12.8 0.4 0.14 12.0 0.4 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AAA_2 PF07724.14 KFX92108.1 - 3.6e-46 157.4 0.3 6e-45 153.4 0.0 2.7 3 0 0 3 3 3 1 AAA domain (Cdc48 subfamily) AAA_lid_9 PF17871.1 KFX92108.1 - 8.9e-34 115.6 0.9 8.9e-34 115.6 0.9 2.5 1 1 0 2 2 2 1 AAA lid domain ClpB_D2-small PF10431.9 KFX92108.1 - 2.3e-26 91.7 0.3 2.3e-26 91.7 0.3 2.2 2 0 0 2 2 1 1 C-terminal, D2-small domain, of ClpB protein AAA PF00004.29 KFX92108.1 - 5.6e-20 72.1 0.1 2.3e-10 41.0 0.0 2.7 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 KFX92108.1 - 2.9e-13 50.0 0.0 7.4e-09 35.7 0.0 2.8 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.26 KFX92108.1 - 4.6e-08 32.9 0.5 2.3e-05 24.2 0.0 2.5 2 1 0 2 2 2 1 Sigma-54 interaction domain AAA_16 PF13191.6 KFX92108.1 - 1.3e-07 32.2 9.0 0.00083 19.8 0.1 4.4 3 2 2 5 5 5 2 AAA ATPase domain NACHT PF05729.12 KFX92108.1 - 1.5e-07 31.4 0.1 0.012 15.5 0.0 2.5 2 0 0 2 2 2 2 NACHT domain ATPase_2 PF01637.18 KFX92108.1 - 1.1e-06 28.8 1.8 1.3 8.9 0.1 3.9 2 2 1 3 3 3 3 ATPase domain predominantly from Archaea AAA_22 PF13401.6 KFX92108.1 - 2.9e-06 27.6 1.5 0.087 13.1 0.0 3.4 3 1 0 3 3 2 2 AAA domain TniB PF05621.11 KFX92108.1 - 6.4e-06 25.7 0.1 0.0022 17.4 0.1 3.6 3 1 0 3 3 2 1 Bacterial TniB protein IstB_IS21 PF01695.17 KFX92108.1 - 7.3e-06 25.8 0.0 0.11 12.3 0.0 2.7 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_7 PF12775.7 KFX92108.1 - 2.4e-05 23.9 0.0 0.25 10.8 0.0 2.5 2 1 0 2 2 2 2 P-loop containing dynein motor region AAA_28 PF13521.6 KFX92108.1 - 5.1e-05 23.6 0.6 0.047 13.9 0.0 3.7 3 0 0 3 3 3 1 AAA domain AAA_14 PF13173.6 KFX92108.1 - 9.7e-05 22.4 0.0 0.79 9.8 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_24 PF13479.6 KFX92108.1 - 0.00056 19.7 0.0 0.41 10.3 0.0 2.4 2 0 0 2 2 2 1 AAA domain ABC_tran PF00005.27 KFX92108.1 - 0.001 19.6 0.3 1 9.9 0.0 3.3 3 0 0 3 3 3 1 ABC transporter Mg_chelatase PF01078.21 KFX92108.1 - 0.0014 18.1 0.0 0.8 9.0 0.0 2.9 2 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_18 PF13238.6 KFX92108.1 - 0.0014 19.1 4.5 1.5 9.4 0.0 3.8 3 1 0 4 4 3 2 AAA domain RNA_helicase PF00910.22 KFX92108.1 - 0.0017 18.7 0.1 0.91 9.9 0.0 3.0 3 1 0 3 3 2 1 RNA helicase RsgA_GTPase PF03193.16 KFX92108.1 - 0.0017 18.3 0.1 1.4 8.8 0.0 2.7 2 0 0 2 2 2 1 RsgA GTPase TsaE PF02367.17 KFX92108.1 - 0.0025 17.8 0.0 3.2 7.8 0.0 2.6 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_30 PF13604.6 KFX92108.1 - 0.0041 16.9 1.7 0.19 11.4 0.4 3.3 3 1 0 3 3 3 1 AAA domain Roc PF08477.13 KFX92108.1 - 0.005 17.1 0.0 2.1 8.6 0.0 2.6 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Zeta_toxin PF06414.12 KFX92108.1 - 0.0055 16.0 0.0 0.38 10.0 0.0 2.4 2 0 0 2 2 2 1 Zeta toxin DUF815 PF05673.13 KFX92108.1 - 0.0059 15.8 0.4 0.1 11.7 0.2 3.1 4 1 0 4 4 4 1 Protein of unknown function (DUF815) AAA_33 PF13671.6 KFX92108.1 - 0.0093 16.1 0.0 7.9 6.6 0.0 2.8 2 0 0 2 2 2 0 AAA domain PhoH PF02562.16 KFX92108.1 - 0.01 15.3 0.0 1.7 8.1 0.0 2.3 2 0 0 2 2 2 0 PhoH-like protein AAA_19 PF13245.6 KFX92108.1 - 0.012 15.9 1.5 0.61 10.4 0.0 3.2 3 1 0 3 3 2 0 AAA domain ResIII PF04851.15 KFX92108.1 - 0.026 14.5 0.2 11 6.0 0.0 3.1 2 1 0 2 2 2 0 Type III restriction enzyme, res subunit SRP54 PF00448.22 KFX92108.1 - 0.034 13.8 0.0 2.4 7.7 0.0 2.4 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain NTPase_1 PF03266.15 KFX92108.1 - 0.041 13.8 0.0 1 9.3 0.0 2.6 2 0 0 2 2 2 0 NTPase AAA_25 PF13481.6 KFX92108.1 - 0.044 13.4 0.1 0.87 9.1 0.0 2.6 2 0 0 2 2 2 0 AAA domain PIF1 PF05970.14 KFX92108.1 - 0.05 12.8 0.0 2.5 7.2 0.0 2.5 3 0 0 3 3 2 0 PIF1-like helicase AAA_21 PF13304.6 KFX92108.1 - 0.054 13.3 1.8 1 9.1 0.0 3.5 3 1 1 4 4 4 0 AAA domain, putative AbiEii toxin, Type IV TA system NB-ARC PF00931.22 KFX92108.1 - 0.06 12.5 0.0 3.1 6.9 0.0 2.4 2 0 0 2 2 2 0 NB-ARC domain RuvB_N PF05496.12 KFX92108.1 - 0.087 12.6 0.1 3.7 7.3 0.0 3.0 3 0 0 3 3 3 0 Holliday junction DNA helicase RuvB P-loop domain AAA_29 PF13555.6 KFX92108.1 - 0.12 12.2 0.1 5.9 6.7 0.0 2.6 3 0 0 3 3 2 0 P-loop containing region of AAA domain DNA_pol3_delta2 PF13177.6 KFX92108.1 - 0.16 11.8 0.0 1.7 8.4 0.0 2.5 2 1 0 2 2 2 0 DNA polymerase III, delta subunit PduV-EutP PF10662.9 KFX92108.1 - 0.19 11.5 0.0 13 5.5 0.0 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation NYD-SP28 PF14772.6 KFX92108.1 - 0.2 11.7 11.0 0.55 10.3 11.0 1.7 1 0 0 1 1 1 0 Sperm tail AAA_23 PF13476.6 KFX92108.1 - 0.41 11.1 17.0 34 4.9 0.0 3.4 2 1 0 2 2 2 0 AAA domain DUF4349 PF14257.6 KFX92108.1 - 0.91 8.9 12.6 3.1 7.2 1.9 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4349) FliL PF03748.14 KFX92108.1 - 1.2 9.8 3.3 17 6.1 0.0 3.2 2 1 0 2 2 2 0 Flagellar basal body-associated protein FliL Seryl_tRNA_N PF02403.22 KFX92108.1 - 3.3 8.0 15.8 8.2 6.7 12.4 3.1 2 1 0 2 2 1 0 Seryl-tRNA synthetase N-terminal domain EF1_GNE PF00736.19 KFX92109.1 - 3.5e-31 107.2 0.8 3.5e-31 107.2 0.8 1.7 2 0 0 2 2 2 1 EF-1 guanine nucleotide exchange domain EF-1_beta_acid PF10587.9 KFX92109.1 - 7.1e-14 52.0 8.1 7.1e-14 52.0 8.1 2.4 2 0 0 2 2 2 1 Eukaryotic elongation factor 1 beta central acidic region GST_C_3 PF14497.6 KFX92109.1 - 0.0004 20.5 0.8 0.0014 18.8 0.0 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 KFX92109.1 - 0.03 14.5 2.3 0.051 13.8 0.2 2.3 2 1 0 2 2 2 0 Glutathione S-transferase, C-terminal domain Cwf_Cwc_15 PF04889.12 KFX92109.1 - 0.041 13.6 0.9 0.051 13.3 0.9 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein GST_C_2 PF13410.6 KFX92109.1 - 0.12 12.4 0.1 1.1 9.4 0.1 2.2 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain PPP4R2 PF09184.11 KFX92113.1 - 9.3e-06 25.4 1.6 2.5e-05 24.0 0.5 2.2 1 1 0 1 1 1 1 PPP4R2 tRNA-synt_2 PF00152.20 KFX92114.1 - 2.3e-81 273.3 0.0 4.9e-67 226.2 0.0 2.1 1 1 1 2 2 2 2 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 KFX92114.1 - 2.8e-09 36.8 0.2 5.1e-09 36.0 0.2 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 KFX92114.1 - 1.4e-07 31.3 0.6 0.015 14.8 0.0 3.5 2 1 1 3 3 3 3 tRNA synthetases class II core domain (F) zf-Tim10_DDP PF02953.15 KFX92115.1 - 3.3e-20 71.5 0.7 3.9e-20 71.3 0.7 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger Tom5 PF10642.9 KFX92115.1 - 0.066 13.3 1.1 0.066 13.3 1.1 1.9 2 0 0 2 2 2 0 Mitochondrial import receptor subunit or translocase DUF1287 PF06940.11 KFX92115.1 - 0.073 12.7 0.0 0.093 12.4 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1287) PG_binding_1 PF01471.18 KFX92116.1 - 0.00027 21.1 0.2 0.27 11.5 0.0 3.2 2 1 0 2 2 2 2 Putative peptidoglycan binding domain Spc7 PF08317.11 KFX92116.1 - 0.011 14.7 5.8 0.017 14.0 5.8 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein BLOC1_2 PF10046.9 KFX92116.1 - 0.04 14.2 9.2 0.13 12.5 6.2 2.6 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF812 PF05667.11 KFX92116.1 - 0.055 12.4 2.0 0.082 11.8 2.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF812) DUF2505 PF10698.9 KFX92116.1 - 0.066 13.3 0.4 0.38 10.8 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2505) XhlA PF10779.9 KFX92116.1 - 0.21 11.8 0.7 0.97 9.7 0.7 2.2 1 1 0 1 1 1 0 Haemolysin XhlA PspA_IM30 PF04012.12 KFX92116.1 - 0.36 10.4 5.3 0.68 9.5 5.3 1.4 1 0 0 1 1 1 0 PspA/IM30 family Jnk-SapK_ap_N PF09744.9 KFX92116.1 - 0.5 10.6 7.2 0.94 9.7 7.2 1.4 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 CLTH PF10607.9 KFX92117.1 - 6.3e-34 117.0 0.0 1e-33 116.3 0.0 1.3 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain zf-RING_UBOX PF13445.6 KFX92117.1 - 8.3e-08 32.1 0.4 1.5e-07 31.3 0.4 1.4 1 0 0 1 1 1 1 RING-type zinc-finger Rtf2 PF04641.12 KFX92117.1 - 0.00011 21.7 0.0 0.00018 20.9 0.0 1.3 1 0 0 1 1 1 1 Rtf2 RING-finger zf-RING_5 PF14634.6 KFX92117.1 - 0.00072 19.5 0.4 0.0012 18.7 0.4 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.6 KFX92117.1 - 0.003 17.9 0.6 0.0052 17.1 0.6 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 KFX92117.1 - 0.0061 16.4 1.4 0.011 15.6 1.4 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KFX92117.1 - 0.0066 16.3 0.5 0.011 15.5 0.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KFX92117.1 - 0.0079 16.0 0.6 0.014 15.2 0.6 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 BAR_3 PF16746.5 KFX92117.1 - 0.009 15.7 0.2 0.02 14.6 0.2 1.5 1 0 0 1 1 1 1 BAR domain of APPL family zf-C3HC4 PF00097.25 KFX92117.1 - 0.063 13.2 0.9 0.11 12.3 0.9 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 KFX92117.1 - 0.087 13.0 0.2 0.2 11.9 0.2 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING PH_6 PF15406.6 KFX92118.1 - 1.9e-35 121.5 0.9 1.9e-35 121.5 0.9 3.1 3 1 0 3 3 3 1 Pleckstrin homology domain PH PF00169.29 KFX92118.1 - 3e-06 27.7 0.0 1.1e-05 25.8 0.0 2.1 1 1 0 1 1 1 1 PH domain 2OG-FeII_Oxy PF03171.20 KFX92123.1 - 2.5e-14 53.6 0.0 4.1e-14 52.9 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily CBFD_NFYB_HMF PF00808.23 KFX92124.1 - 8.1e-10 38.9 0.0 1.6e-09 37.9 0.0 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 KFX92124.1 - 2.7e-07 31.0 0.4 1.2e-06 28.9 0.0 1.9 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 CENP-T_C PF15511.6 KFX92124.1 - 2e-06 27.9 0.0 2.6e-05 24.3 0.0 2.0 1 1 1 2 2 2 1 Centromere kinetochore component CENP-T histone fold TAFII28 PF04719.14 KFX92124.1 - 0.012 15.7 0.0 0.019 15.0 0.0 1.3 1 0 0 1 1 1 0 hTAFII28-like protein conserved region Bromo_TP PF07524.13 KFX92124.1 - 0.013 15.5 0.0 0.028 14.4 0.0 1.6 1 0 0 1 1 1 0 Bromodomain associated PPE PF00823.19 KFX92124.1 - 0.02 15.0 0.2 0.032 14.3 0.2 1.3 1 0 0 1 1 1 0 PPE family BBS2_N PF14781.6 KFX92124.1 - 0.12 12.3 0.2 0.68 9.9 0.1 2.0 1 1 1 2 2 2 0 Ciliary BBSome complex subunit 2, N-terminal CENP-X PF09415.10 KFX92124.1 - 0.3 11.4 3.2 1.7 9.0 0.0 2.6 3 0 0 3 3 3 0 CENP-S associating Centromere protein X Melibiase_2 PF16499.5 KFX92125.1 - 1.7e-54 184.9 7.0 6e-37 127.3 0.4 2.4 2 0 0 2 2 2 2 Alpha galactosidase A Ank_2 PF12796.7 KFX92125.1 - 1.2e-22 80.2 0.1 4.4e-08 33.6 0.0 3.8 3 0 0 3 3 3 3 Ankyrin repeats (3 copies) Fungal_trans PF04082.18 KFX92125.1 - 6.4e-19 68.0 0.0 1.2e-18 67.1 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Ank_4 PF13637.6 KFX92125.1 - 3.7e-16 59.3 0.2 5.9e-06 26.7 0.0 4.2 4 0 0 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFX92125.1 - 2.1e-15 55.3 0.1 0.023 15.2 0.0 6.3 6 0 0 6 6 5 4 Ankyrin repeat Ank PF00023.30 KFX92125.1 - 1.3e-10 41.2 0.0 0.015 15.8 0.0 5.9 5 0 0 5 5 5 2 Ankyrin repeat Zn_clus PF00172.18 KFX92125.1 - 1.6e-09 37.7 11.7 4.2e-09 36.4 11.7 1.8 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Melibiase_C PF17801.1 KFX92125.1 - 4.9e-09 36.1 0.2 1.7e-08 34.4 0.1 2.1 2 0 0 2 2 2 1 Alpha galactosidase C-terminal beta sandwich domain Ank_5 PF13857.6 KFX92125.1 - 8.2e-08 32.4 0.3 0.21 12.0 0.0 5.2 4 1 1 5 5 5 3 Ankyrin repeats (many copies) Helo_like_N PF17111.5 KFX92125.1 - 1.6e-05 24.4 0.9 1.6e-05 24.4 0.9 2.2 2 0 0 2 2 2 1 Fungal N-terminal domain of STAND proteins Melibiase PF02065.18 KFX92125.1 - 1.9e-05 23.8 0.0 3.7e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 Melibiase SesA PF17107.5 KFX92125.1 - 5.9e-05 23.2 1.6 5.9e-05 23.2 1.6 2.3 2 0 0 2 2 2 1 N-terminal domain on NACHT_NTPase and P-loop NTPases BTAD PF03704.17 KFX92125.1 - 0.084 13.3 0.9 8.2 6.9 0.0 2.5 2 0 0 2 2 2 0 Bacterial transcriptional activator domain DUF2383 PF09537.10 KFX92125.1 - 0.21 12.0 2.0 0.37 11.2 0.3 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF2383) Alpha-amylase PF00128.24 KFX92126.1 - 2.1e-23 83.4 1.0 4.4e-23 82.4 1.0 1.5 1 1 0 1 1 1 1 Alpha amylase, catalytic domain DUF1939 PF09154.10 KFX92126.1 - 0.00032 20.8 0.5 0.0009 19.4 0.2 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF1939) Glyco_hydro_70 PF02324.16 KFX92126.1 - 0.00035 18.9 0.1 1.7 6.8 0.0 3.0 3 0 0 3 3 3 3 Glycosyl hydrolase family 70 AMPK1_CBM PF16561.5 KFX92134.1 - 8.1e-22 77.2 1.0 1.4e-21 76.5 1.0 1.3 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase CBM53 PF16760.5 KFX92134.1 - 0.029 14.9 0.6 0.066 13.8 0.6 1.6 1 0 0 1 1 1 0 Starch/carbohydrate-binding module (family 53) CBM_48 PF02922.18 KFX92134.1 - 0.041 14.2 0.1 0.079 13.3 0.1 1.4 1 0 0 1 1 1 0 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) Ten1 PF12658.7 KFX92135.1 - 1.8e-23 82.8 0.0 2.1e-23 82.6 0.0 1.1 1 0 0 1 1 1 1 Telomere capping, CST complex subunit Ten1_2 PF15490.6 KFX92135.1 - 0.00065 19.4 0.0 0.0013 18.4 0.0 1.6 1 1 0 1 1 1 1 Telomere-capping, CST complex subunit MotB_plug PF13677.6 KFX92135.1 - 0.047 13.3 0.0 0.092 12.4 0.0 1.5 1 0 0 1 1 1 0 Membrane MotB of proton-channel complex MotA/MotB SAM_decarbox PF01536.16 KFX92142.1 - 6e-133 443.3 0.0 7.4e-133 442.9 0.0 1.1 1 0 0 1 1 1 1 Adenosylmethionine decarboxylase PAP_assoc PF03828.19 KFX92144.1 - 1.9e-16 60.0 0.0 2.4e-15 56.5 0.0 2.4 1 1 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.23 KFX92144.1 - 2.3e-05 24.6 0.0 7.9e-05 22.9 0.0 2.0 1 0 0 1 1 1 1 Nucleotidyltransferase domain Retrotrans_gag PF03732.17 KFX92144.1 - 0.001 19.3 0.1 0.31 11.3 0.0 2.8 2 0 0 2 2 2 2 Retrotransposon gag protein RGS-like PF09128.11 KFX92144.1 - 0.0019 17.9 0.3 0.0019 17.9 0.3 1.6 2 0 0 2 2 2 1 Regulator of G protein signalling-like domain Polbeta PF18765.1 KFX92144.1 - 0.0033 17.5 0.0 0.026 14.6 0.0 2.3 2 0 0 2 2 2 1 Polymerase beta, Nucleotidyltransferase MFS_1 PF07690.16 KFX92147.1 - 6.2e-37 127.3 30.9 3e-28 98.8 4.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KFX92147.1 - 1.2e-09 37.6 6.0 1.2e-09 37.6 6.0 3.1 2 1 1 3 3 3 1 Sugar (and other) transporter TRI12 PF06609.13 KFX92147.1 - 0.011 14.2 0.7 0.011 14.2 0.7 1.8 2 0 0 2 2 2 0 Fungal trichothecene efflux pump (TRI12) TFR_dimer PF04253.15 KFX92148.1 - 1.6e-26 92.8 0.0 2.7e-26 92.0 0.0 1.3 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain Peptidase_M28 PF04389.17 KFX92148.1 - 2.6e-21 76.2 0.0 4.2e-21 75.5 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.22 KFX92148.1 - 1.3e-07 31.5 0.1 6.2e-07 29.3 0.0 2.1 2 0 0 2 2 2 1 PA domain Nicastrin PF05450.15 KFX92148.1 - 0.069 12.6 0.0 0.14 11.6 0.0 1.4 1 0 0 1 1 1 0 Nicastrin IMPDH PF00478.25 KFX92154.1 - 1e-124 416.0 6.7 1.2e-124 415.8 6.7 1.1 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain CBS PF00571.28 KFX92154.1 - 1.5e-15 57.4 0.0 1.7e-07 31.5 0.0 2.4 2 0 0 2 2 2 2 CBS domain NMO PF03060.15 KFX92154.1 - 2.6e-09 36.9 4.7 0.00034 20.1 0.0 2.8 2 1 1 3 3 3 2 Nitronate monooxygenase FMN_dh PF01070.18 KFX92154.1 - 1.2e-06 27.9 0.8 8e-06 25.1 0.3 2.3 3 0 0 3 3 3 1 FMN-dependent dehydrogenase YpsA PF06908.11 KFX92154.1 - 0.023 14.7 0.0 0.046 13.7 0.0 1.4 1 0 0 1 1 1 0 YspA SLOG family His_biosynth PF00977.21 KFX92154.1 - 0.024 14.1 2.1 0.67 9.4 0.1 2.4 1 1 0 2 2 2 0 Histidine biosynthesis protein NanE PF04131.14 KFX92154.1 - 0.041 13.1 0.2 0.08 12.1 0.2 1.4 1 0 0 1 1 1 0 Putative N-acetylmannosamine-6-phosphate epimerase PK PF00224.21 KFX92154.1 - 0.06 12.2 0.0 0.18 10.7 0.0 1.7 1 1 0 1 1 1 0 Pyruvate kinase, barrel domain Choline_kin_N PF04428.14 KFX92154.1 - 0.18 11.5 0.1 0.41 10.4 0.1 1.6 1 0 0 1 1 1 0 Choline kinase N terminus RasGAP PF00616.19 KFX92155.1 - 3.1e-52 177.3 0.0 6.7e-52 176.2 0.0 1.6 1 0 0 1 1 1 1 GTPase-activator protein for Ras-like GTPase RasGAP_C PF03836.15 KFX92155.1 - 3.7e-47 159.9 2.2 1.3e-46 158.1 2.2 2.1 1 0 0 1 1 1 1 RasGAP C-terminus IQ PF00612.27 KFX92155.1 - 1.9e-12 45.8 22.9 0.33 10.8 0.3 10.8 11 0 0 11 11 11 6 IQ calmodulin-binding motif CH PF00307.31 KFX92155.1 - 1.2e-10 41.5 0.0 4.1e-10 39.8 0.0 1.9 1 0 0 1 1 1 1 Calponin homology (CH) domain TetR_C_21 PF17926.1 KFX92156.1 - 0.26 11.4 1.2 0.26 11.4 0.1 1.5 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain Pro_CA PF00484.19 KFX92160.1 - 1.9e-28 99.7 0.0 2.5e-28 99.3 0.0 1.1 1 0 0 1 1 1 1 Carbonic anhydrase Zn_clus PF00172.18 KFX92161.1 - 5.5e-09 36.0 7.3 5.5e-09 36.0 7.3 1.7 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain NTP_transf_9 PF04248.12 KFX92163.1 - 1.5e-32 111.3 2.0 1.7e-32 111.2 2.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF427) Pyridoxal_deC PF00282.19 KFX92164.1 - 1.5e-108 362.9 0.0 1.8e-108 362.6 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Got1 PF04178.12 KFX92165.1 - 1e-14 54.9 13.5 1.3e-14 54.6 13.5 1.1 1 0 0 1 1 1 1 Got1/Sft2-like family DUF373 PF04123.13 KFX92165.1 - 1.5 8.2 4.7 0.32 10.4 1.0 1.6 1 1 0 2 2 2 0 Domain of unknown function (DUF373) YL1_C PF08265.11 KFX92166.1 - 2.1e-15 56.2 0.2 3.2e-15 55.6 0.2 1.3 1 0 0 1 1 1 1 YL1 nuclear protein C-terminal domain DASH_Dad4 PF08650.10 KFX92167.1 - 7.7e-33 112.3 5.9 8.4e-33 112.2 5.9 1.0 1 0 0 1 1 1 1 DASH complex subunit Dad4 GM_CSF PF01109.17 KFX92167.1 - 0.01 16.0 0.3 0.012 15.8 0.3 1.1 1 0 0 1 1 1 0 Granulocyte-macrophage colony-stimulating factor LTD PF00932.19 KFX92167.1 - 0.098 13.0 0.1 0.1 13.0 0.1 1.1 1 0 0 1 1 1 0 Lamin Tail Domain Choline_kinase PF01633.20 KFX92177.1 - 9.7e-18 64.5 0.1 1.5e-17 63.9 0.1 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.23 KFX92177.1 - 6.8e-05 22.9 0.0 0.00011 22.2 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family GPR_Gpa2_C PF11970.8 KFX92177.1 - 0.0011 18.9 0.4 0.0024 17.9 0.4 1.5 1 0 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 C-term Pkinase_fungal PF17667.1 KFX92177.1 - 0.074 11.8 0.0 0.11 11.3 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase Med15_fungi PF05397.12 KFX92181.1 - 9.1e-05 22.7 1.7 9.1e-05 22.7 1.7 6.0 8 0 0 8 8 8 1 Mediator complex subunit 15 Whi5 PF08528.11 KFX92182.1 - 3.1e-08 33.0 0.3 4.9e-08 32.4 0.3 1.3 1 0 0 1 1 1 1 Whi5 like DUF1768 PF08719.11 KFX92190.1 - 1.5e-37 129.3 0.0 2.6e-37 128.5 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1768) PEP-CTERM PF07589.11 KFX92190.1 - 0.027 14.6 0.2 0.085 13.0 0.2 1.8 1 0 0 1 1 1 0 PEP-CTERM motif Vinculin PF01044.19 KFX92190.1 - 1.2 7.3 11.0 1.5 6.9 11.0 1.1 1 0 0 1 1 1 0 Vinculin family TFIIA PF03153.13 KFX92190.1 - 2 8.3 22.2 2.3 8.1 22.2 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit RR_TM4-6 PF06459.12 KFX92190.1 - 4.5 7.0 22.8 8.2 6.2 22.8 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 RNA_polI_A34 PF08208.11 KFX92190.1 - 7.7 6.5 30.8 13 5.8 30.8 1.4 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 AAA PF00004.29 KFX92191.1 - 3.6e-40 137.4 0.0 7.7e-40 136.4 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_ID_OB PF16450.5 KFX92191.1 - 1.2e-18 66.8 0.2 2.3e-18 65.9 0.2 1.5 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_lid_3 PF17862.1 KFX92191.1 - 1.3e-09 37.7 0.0 2.8e-09 36.6 0.0 1.6 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 KFX92191.1 - 0.00021 21.7 2.1 0.022 15.1 0.0 2.8 2 1 1 3 3 3 1 AAA ATPase domain AAA_5 PF07728.14 KFX92191.1 - 0.00022 21.3 0.1 0.0012 18.9 0.1 2.3 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 KFX92191.1 - 0.00036 20.3 0.0 0.00082 19.1 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_2 PF07724.14 KFX92191.1 - 0.00052 20.2 0.9 0.0057 16.8 0.0 3.0 3 1 0 3 3 3 1 AAA domain (Cdc48 subfamily) PhoH PF02562.16 KFX92191.1 - 0.0018 17.8 0.2 0.053 13.0 0.1 2.3 2 0 0 2 2 2 1 PhoH-like protein AAA_22 PF13401.6 KFX92191.1 - 0.0024 18.1 3.3 0.084 13.1 0.0 3.2 3 1 1 4 4 4 1 AAA domain Mg_chelatase PF01078.21 KFX92191.1 - 0.01 15.2 0.0 0.028 13.8 0.0 1.7 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_33 PF13671.6 KFX92191.1 - 0.015 15.5 0.0 0.034 14.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain DUF815 PF05673.13 KFX92191.1 - 0.024 13.8 0.0 0.058 12.5 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF815) IstB_IS21 PF01695.17 KFX92191.1 - 0.076 12.7 0.1 0.18 11.6 0.1 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_7 PF12775.7 KFX92191.1 - 0.1 12.1 0.0 0.32 10.5 0.0 1.8 1 1 0 1 1 1 0 P-loop containing dynein motor region AAA_11 PF13086.6 KFX92191.1 - 0.5 10.1 0.0 0.5 10.1 0.0 2.8 2 1 1 3 3 3 0 AAA domain SKG6 PF08693.10 KFX92194.1 - 0.11 12.0 2.7 0.18 11.2 2.7 1.3 1 0 0 1 1 1 0 Transmembrane alpha-helix domain GT87 PF09594.10 KFX92194.1 - 0.43 10.3 3.6 0.53 10.0 3.6 1.1 1 0 0 1 1 1 0 Glycosyltransferase family 87 Peptidase_C12 PF01088.21 KFX92196.1 - 7.4e-58 195.8 0.0 9.2e-58 195.4 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 MFS_1 PF07690.16 KFX92197.1 - 1.2e-31 110.0 25.8 1.2e-31 110.0 25.8 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KFX92197.1 - 8.2e-18 64.5 1.8 8.2e-18 64.5 1.8 3.0 3 1 0 3 3 3 2 Sugar (and other) transporter Glyoxalase PF00903.25 KFX92198.1 - 9e-10 38.8 2.3 1.9e-09 37.8 2.3 1.6 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 KFX92198.1 - 0.0052 17.0 0.2 0.04 14.2 0.2 2.4 2 1 0 2 2 2 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Response_reg PF00072.24 KFX92199.1 - 1.6e-13 50.8 0.0 2.2e-13 50.4 0.0 1.2 1 0 0 1 1 1 1 Response regulator receiver domain Hydrolase PF00702.26 KFX92201.1 - 1.6e-06 28.6 0.0 3.5e-05 24.2 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 KFX92201.1 - 2.3e-05 24.6 0.0 4.6e-05 23.6 0.0 1.5 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase HAD PF12710.7 KFX92201.1 - 0.074 13.5 0.0 0.078 13.4 0.0 1.2 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase Consortin_C PF15281.6 KFX92202.1 - 1.9 8.5 3.0 1.9 8.5 1.8 1.5 1 1 0 1 1 1 0 Consortin C-terminus Aldose_epim PF01263.20 KFX92204.1 - 1.9e-59 201.5 0.0 2.5e-59 201.1 0.0 1.1 1 0 0 1 1 1 1 Aldose 1-epimerase DUF3767 PF12597.8 KFX92205.1 - 2.4e-34 117.2 0.1 2.4e-34 117.2 0.1 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF3767) DUF1744 PF08490.12 KFX92206.1 - 1.1e-160 534.6 0.0 1.8e-160 533.9 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1744) DNA_pol_B_exo1 PF03104.19 KFX92206.1 - 1.5e-79 267.6 0.2 2.5e-79 266.9 0.2 1.4 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain NMT1 PF09084.11 KFX92206.1 - 6.8e-77 258.2 0.0 1.8e-76 256.9 0.0 1.7 2 0 0 2 2 2 1 NMT1/THI5 like DNA_pol_B PF00136.21 KFX92206.1 - 1.3e-14 53.7 0.1 5.3e-13 48.5 0.1 3.2 3 1 0 3 3 3 1 DNA polymerase family B DNA_pol_B_exo2 PF10108.9 KFX92206.1 - 4.4e-09 36.3 0.3 1.3e-08 34.8 0.3 1.8 1 0 0 1 1 1 1 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB RNase_H_2 PF13482.6 KFX92206.1 - 4.9e-06 26.6 0.0 1.9e-05 24.7 0.0 2.1 1 0 0 1 1 1 1 RNase_H superfamily NMT1_2 PF13379.6 KFX92206.1 - 0.058 13.1 0.1 0.42 10.3 0.0 2.4 2 1 1 3 3 3 0 NMT1-like family DNA_pol3_alpha PF07733.12 KFX92206.1 - 0.09 12.3 0.0 0.2 11.2 0.0 1.5 1 0 0 1 1 1 0 Bacterial DNA polymerase III alpha NTPase domain FtsJ PF01728.19 KFX92207.1 - 8.4e-12 45.5 0.0 1.2e-11 45.0 0.0 1.2 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltr_RsmB-F PF01189.17 KFX92207.1 - 0.17 11.5 0.1 0.3 10.7 0.1 1.4 1 0 0 1 1 1 0 16S rRNA methyltransferase RsmB/F Sec62 PF03839.16 KFX92212.1 - 4.2e-72 242.2 0.1 4.2e-72 242.2 0.1 1.7 2 0 0 2 2 2 1 Translocation protein Sec62 HicB PF05534.12 KFX92212.1 - 0.098 12.5 0.0 0.22 11.4 0.0 1.6 1 0 0 1 1 1 0 HicB family HA2 PF04408.23 KFX92223.1 - 4.4e-16 59.1 0.2 1.1e-15 57.9 0.2 1.7 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 KFX92223.1 - 1.8e-12 47.4 0.0 4.1e-12 46.3 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 KFX92223.1 - 6.4e-12 45.8 0.0 1.4e-11 44.7 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_22 PF13401.6 KFX92223.1 - 3.4e-05 24.2 0.1 9e-05 22.8 0.1 1.7 1 0 0 1 1 1 1 AAA domain DEAD PF00270.29 KFX92223.1 - 0.00028 20.7 0.1 0.00065 19.5 0.1 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_30 PF13604.6 KFX92223.1 - 0.00038 20.2 0.1 0.00069 19.4 0.1 1.3 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KFX92223.1 - 0.0038 17.6 0.4 0.053 13.8 0.1 2.4 2 1 0 2 2 2 1 AAA domain AAA_14 PF13173.6 KFX92223.1 - 0.021 14.8 0.1 8.7 6.4 0.0 2.4 1 1 1 2 2 2 0 AAA domain ABC_tran PF00005.27 KFX92223.1 - 0.032 14.8 0.1 0.11 13.0 0.1 2.0 1 1 0 1 1 1 0 ABC transporter GDI PF00996.18 KFX92223.1 - 0.061 11.8 0.0 0.11 11.0 0.0 1.3 1 0 0 1 1 1 0 GDP dissociation inhibitor Zeta_toxin PF06414.12 KFX92223.1 - 0.13 11.6 0.1 0.31 10.3 0.0 1.6 1 1 0 1 1 1 0 Zeta toxin NmrA PF05368.13 KFX92224.1 - 2.6e-12 46.8 0.0 3.9e-12 46.2 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family Semialdhyde_dh PF01118.24 KFX92224.1 - 0.016 15.6 0.1 0.055 13.9 0.1 2.0 1 1 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain NAD_binding_10 PF13460.6 KFX92224.1 - 0.022 14.7 0.2 0.19 11.6 0.2 2.7 1 1 0 1 1 1 0 NAD(P)H-binding RhgB_N PF09284.10 KFX92229.1 - 2e-106 355.2 5.2 3.1e-106 354.5 5.2 1.3 1 0 0 1 1 1 1 Rhamnogalacturonan lyase B, N-terminal CBM-like PF14683.6 KFX92229.1 - 3.3e-44 150.7 0.1 1e-43 149.1 0.0 1.9 2 0 0 2 2 2 1 Polysaccharide lyase family 4, domain III fn3_3 PF14686.6 KFX92229.1 - 6.9e-21 73.8 3.9 6.9e-21 73.8 3.9 2.9 3 1 0 3 3 3 1 Polysaccharide lyase family 4, domain II CarboxypepD_reg PF13620.6 KFX92229.1 - 3.2e-05 24.1 1.8 3.2e-05 24.1 1.8 3.9 6 0 0 6 6 6 1 Carboxypeptidase regulatory-like domain DUF2012 PF09430.10 KFX92229.1 - 0.037 14.2 0.0 0.11 12.7 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2012) Pkinase PF00069.25 KFX92230.1 - 2.2e-53 181.3 0.0 3.9e-35 121.5 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KFX92230.1 - 1.7e-22 79.9 0.0 1.3e-20 73.7 0.0 3.2 2 1 0 2 2 2 1 Protein tyrosine kinase APH PF01636.23 KFX92230.1 - 0.00022 21.2 0.0 0.0027 17.7 0.0 2.6 3 0 0 3 3 3 1 Phosphotransferase enzyme family Kinase-like PF14531.6 KFX92230.1 - 0.00078 18.8 0.0 0.0022 17.3 0.0 1.7 1 1 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 KFX92230.1 - 0.0025 16.7 0.0 0.0066 15.3 0.0 1.6 2 0 0 2 2 2 1 Fungal protein kinase MFS_1 PF07690.16 KFX92235.1 - 4.5e-10 39.0 8.5 4.5e-10 39.0 8.5 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily DUF4131 PF13567.6 KFX92235.1 - 3.6 7.2 5.1 3.3 7.3 0.1 3.0 3 2 0 3 3 3 0 Domain of unknown function (DUF4131) zf-C2H2_4 PF13894.6 KFX92236.1 - 0.0047 17.7 0.7 0.0047 17.7 0.7 1.8 2 0 0 2 2 2 1 C2H2-type zinc finger Fibrillarin_2 PF10113.9 KFX92236.1 - 0.0053 15.4 0.1 0.007 15.1 0.1 1.1 1 0 0 1 1 1 1 Fibrillarin-like archaeal protein zf-C2H2 PF00096.26 KFX92236.1 - 0.01 16.2 0.6 0.025 15.0 0.6 1.7 1 0 0 1 1 1 0 Zinc finger, C2H2 type P_C PF06640.11 KFX92236.1 - 0.048 13.8 2.3 0.081 13.1 2.3 1.3 1 0 0 1 1 1 0 P protein C-terminus zf-C2H2_jaz PF12171.8 KFX92236.1 - 0.074 13.4 0.3 0.13 12.6 0.3 1.3 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding TPR_12 PF13424.6 KFX92237.1 - 5.3e-17 61.9 1.2 1.7e-08 34.6 0.1 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_10 PF13374.6 KFX92237.1 - 1.2e-08 34.6 6.1 0.0016 18.2 0.0 3.7 4 0 0 4 4 4 2 Tetratricopeptide repeat zf-C2H2_4 PF13894.6 KFX92237.1 - 1.1e-05 25.8 31.1 0.038 14.8 1.7 4.9 4 0 0 4 4 4 3 C2H2-type zinc finger TPR_7 PF13176.6 KFX92237.1 - 3e-05 23.8 0.5 0.26 11.4 0.0 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 KFX92237.1 - 0.00037 20.5 1.6 1.8 9.0 0.1 3.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.28 KFX92237.1 - 0.00061 19.5 1.0 1.5 8.8 0.0 4.0 4 0 0 4 4 4 1 Tetratricopeptide repeat zf-C2H2 PF00096.26 KFX92237.1 - 0.00087 19.6 33.1 0.013 15.9 1.9 4.8 4 0 0 4 4 4 2 Zinc finger, C2H2 type TPR_2 PF07719.17 KFX92237.1 - 0.0027 17.7 1.4 12 6.3 0.1 4.0 4 0 0 4 4 4 1 Tetratricopeptide repeat DCAF15_WD40 PF14939.6 KFX92237.1 - 0.0049 16.5 1.7 0.011 15.4 1.7 1.5 1 0 0 1 1 1 1 DDB1-and CUL4-substrate receptor 15, WD repeat zf-C2H2_jaz PF12171.8 KFX92237.1 - 0.015 15.6 0.7 0.015 15.6 0.7 4.8 4 0 0 4 4 4 0 Zinc-finger double-stranded RNA-binding zf-C2H2_8 PF15909.5 KFX92237.1 - 2 8.8 10.0 4.6 7.6 2.0 3.0 2 1 1 3 3 3 0 C2H2-type zinc ribbon zf-P11 PF03854.14 KFX92237.1 - 2.5 7.8 10.2 0.066 12.9 2.2 2.5 3 0 0 3 3 3 0 P-11 zinc finger Beta-lactamase PF00144.24 KFX92238.1 - 2.1e-44 152.1 0.0 2.5e-44 151.9 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase Peptidase_S11 PF00768.20 KFX92238.1 - 0.0038 16.7 0.0 0.0061 16.0 0.0 1.2 1 0 0 1 1 1 1 D-alanyl-D-alanine carboxypeptidase Peptidase_C48 PF02902.19 KFX92240.1 - 7.4e-26 91.3 0.0 1.6e-25 90.2 0.0 1.6 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain DSPc PF00782.20 KFX92242.1 - 1.6e-27 95.9 0.0 1.2e-18 67.2 0.0 2.3 2 0 0 2 2 2 2 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 KFX92242.1 - 0.0019 17.8 0.1 0.009 15.6 0.1 1.9 2 0 0 2 2 2 1 Protein-tyrosine phosphatase DNA_pol_delta_4 PF04081.13 KFX92243.1 - 1.9e-34 118.8 0.5 2.6e-34 118.4 0.5 1.3 1 0 0 1 1 1 1 DNA polymerase delta, subunit 4 TPR_19 PF14559.6 KFX92244.1 - 1.3e-10 41.6 3.6 2.5e-06 27.9 0.5 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_6 PF13174.6 KFX92244.1 - 1e-05 25.9 2.0 0.72 10.6 0.0 4.5 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.6 KFX92244.1 - 0.00021 21.9 11.7 0.43 11.5 0.0 5.4 4 2 2 6 6 6 2 Tetratricopeptide repeat Coatomer_E PF04733.14 KFX92244.1 - 0.00035 20.1 0.1 0.00053 19.5 0.1 1.3 1 1 0 1 1 1 1 Coatomer epsilon subunit TPR_2 PF07719.17 KFX92244.1 - 0.00052 19.9 8.5 3.1 8.1 0.0 5.4 5 0 0 5 5 5 1 Tetratricopeptide repeat ANAPC3 PF12895.7 KFX92244.1 - 0.027 14.7 2.3 1.2 9.4 0.0 3.0 3 0 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.6 KFX92244.1 - 0.13 12.5 0.2 0.13 12.5 0.2 2.9 5 0 0 5 5 5 0 Tetratricopeptide repeat ORC3_N PF07034.11 KFX92244.1 - 0.18 10.9 0.1 0.29 10.2 0.1 1.2 1 0 0 1 1 1 0 Origin recognition complex (ORC) subunit 3 N-terminus TPR_16 PF13432.6 KFX92244.1 - 0.89 10.3 16.3 4.8 7.9 0.3 4.9 6 1 0 6 6 6 0 Tetratricopeptide repeat TPR_1 PF00515.28 KFX92244.1 - 9 6.3 7.3 17 5.5 0.0 4.1 5 0 0 5 5 5 0 Tetratricopeptide repeat Glyco_hydro_28 PF00295.17 KFX92245.1 - 2.4e-39 135.3 5.9 9.5e-39 133.3 5.9 1.7 1 1 0 1 1 1 1 Glycosyl hydrolases family 28 DUF2672 PF10878.8 KFX92245.1 - 0.081 12.9 0.0 0.18 11.7 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2672) Phage_Treg PF04761.12 KFX92245.1 - 0.11 12.6 0.2 1.2 9.3 0.2 2.3 2 0 0 2 2 2 0 Lactococcus bacteriophage putative transcription regulator Solute_trans_a PF03619.16 KFX92268.1 - 8.3e-87 291.1 27.6 9.6e-87 290.9 27.6 1.0 1 0 0 1 1 1 1 Organic solute transporter Ostalpha Myb_DNA-bind_6 PF13921.6 KFX92275.1 - 0.00097 19.3 0.0 0.0014 18.9 0.0 1.3 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 KFX92275.1 - 0.0076 16.4 1.2 0.04 14.1 1.2 2.0 1 1 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_4 PF13837.6 KFX92275.1 - 0.021 15.2 0.0 0.035 14.5 0.0 1.4 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain DUP PF00674.18 KFX92275.1 - 0.081 13.1 0.4 0.22 11.7 0.4 1.7 1 1 0 1 1 1 0 DUP family Myb_DNA-bind_3 PF12776.7 KFX92275.1 - 0.14 13.1 0.1 0.24 12.4 0.1 1.4 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain Atg29_N PF18388.1 KFX92275.1 - 0.16 11.8 0.3 0.27 11.1 0.3 1.4 1 0 0 1 1 1 0 Atg29 N-terminal domain TFIIA PF03153.13 KFX92280.1 - 0.97 9.4 11.1 1.4 8.8 11.1 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SOG2 PF10428.9 KFX92280.1 - 3.1 6.9 53.2 5.5 6.1 53.2 1.4 1 0 0 1 1 1 0 RAM signalling pathway protein Utp14 PF04615.13 KFX92280.1 - 4.3 5.8 16.0 5.4 5.5 16.0 1.0 1 0 0 1 1 1 0 Utp14 protein Gtr1_RagA PF04670.12 KFX92281.1 - 1.2e-91 306.2 0.0 2.1e-91 305.4 0.0 1.4 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region DUF1275 PF06912.11 KFX92281.1 - 4.7e-30 105.0 25.1 2.3e-29 102.7 15.5 3.3 2 1 0 2 2 2 1 Protein of unknown function (DUF1275) 60KD_IMP PF02096.20 KFX92281.1 - 2.3e-16 60.1 0.3 4.2e-16 59.3 0.3 1.4 1 0 0 1 1 1 1 60Kd inner membrane protein Roc PF08477.13 KFX92281.1 - 2.3e-07 31.0 0.0 5.5e-07 29.8 0.0 1.7 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 KFX92281.1 - 2.3e-06 27.6 0.0 8.7e-06 25.8 0.0 2.0 1 0 0 1 1 1 1 50S ribosome-binding GTPase Arf PF00025.21 KFX92281.1 - 4.4e-06 26.3 0.0 7.9e-06 25.4 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.22 KFX92281.1 - 1.3e-05 24.8 0.0 2.7e-05 23.8 0.0 1.5 1 0 0 1 1 1 1 Ras family RsgA_GTPase PF03193.16 KFX92281.1 - 0.00092 19.2 0.1 0.69 9.8 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase G-alpha PF00503.20 KFX92281.1 - 0.022 13.9 2.2 2.1 7.4 0.8 2.2 1 1 1 2 2 2 0 G-protein alpha subunit AAA_29 PF13555.6 KFX92281.1 - 0.028 14.2 0.4 0.17 11.6 0.1 2.3 2 0 0 2 2 2 0 P-loop containing region of AAA domain DUF815 PF05673.13 KFX92281.1 - 0.029 13.5 0.0 0.05 12.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) ABC_tran PF00005.27 KFX92281.1 - 0.049 14.2 0.0 0.12 12.8 0.0 1.6 1 0 0 1 1 1 0 ABC transporter Borrelia_P83 PF05262.11 KFX92281.1 - 3.3 6.1 8.1 5.6 5.3 8.1 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein PEP_mutase PF13714.6 KFX92282.1 - 2e-41 142.0 0.2 2.5e-41 141.7 0.2 1.1 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase ICL PF00463.21 KFX92282.1 - 9.5e-23 80.5 0.6 1.4e-22 79.9 0.2 1.4 2 0 0 2 2 2 1 Isocitrate lyase family TGT PF01702.18 KFX92283.1 - 1.9e-59 201.6 0.0 2.3e-59 201.3 0.0 1.0 1 0 0 1 1 1 1 Queuine tRNA-ribosyltransferase LCCL PF03815.19 KFX92284.1 - 2.2e-21 75.8 0.2 3.7e-21 75.0 0.2 1.3 1 0 0 1 1 1 1 LCCL domain DUF1688 PF07958.11 KFX92285.1 - 1e-183 610.8 0.0 1.2e-183 610.6 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1688) RRM_1 PF00076.22 KFX92288.1 - 1.1e-08 34.8 0.0 2.9e-08 33.4 0.0 1.7 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KFX92288.1 - 1.2e-05 24.9 0.0 1.9e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Calcipressin PF04847.12 KFX92288.1 - 0.08 12.7 0.3 0.27 11.0 0.0 1.9 2 0 0 2 2 2 0 Calcipressin Limkain-b1 PF11608.8 KFX92288.1 - 0.094 12.8 0.1 0.23 11.6 0.0 1.7 2 0 0 2 2 2 0 Limkain b1 SET_assoc PF11767.8 KFX92288.1 - 0.1 12.3 0.0 0.17 11.5 0.0 1.4 1 0 0 1 1 1 0 Histone lysine methyltransferase SET associated Glyco_hydro_47 PF01532.20 KFX92289.1 - 1.2e-167 558.5 0.0 1.5e-167 558.1 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 GST_N_3 PF13417.6 KFX92291.1 - 1.7e-15 57.1 0.0 2.8e-15 56.5 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 KFX92291.1 - 9.3e-15 54.7 0.1 1.7e-13 50.7 0.0 2.2 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KFX92291.1 - 8.4e-12 45.2 0.0 1.7e-11 44.3 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 KFX92291.1 - 2e-08 34.3 0.1 3.2e-08 33.7 0.1 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KFX92291.1 - 5.5e-08 32.9 0.0 9.7e-08 32.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 KFX92291.1 - 0.00075 19.5 0.2 0.0012 18.8 0.2 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_4 PF17172.4 KFX92291.1 - 0.0032 18.2 0.0 0.012 16.3 0.0 1.9 1 1 0 1 1 1 1 Glutathione S-transferase N-terminal domain Tom37 PF10568.9 KFX92291.1 - 0.0097 16.2 0.0 0.014 15.7 0.0 1.3 1 0 0 1 1 1 1 Outer mitochondrial membrane transport complex protein Plant_NMP1 PF06694.11 KFX92291.1 - 0.012 14.8 0.0 0.016 14.3 0.0 1.2 1 0 0 1 1 1 0 Plant nuclear matrix protein 1 (NMP1) GMC_oxred_N PF00732.19 KFX92292.1 - 7.8e-56 189.6 0.0 1.1e-55 189.1 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KFX92292.1 - 1.4e-34 119.7 0.1 3e-34 118.6 0.1 1.6 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 KFX92292.1 - 7.8e-09 35.1 0.1 5.2e-07 29.1 0.1 2.5 1 1 0 1 1 1 1 FAD binding domain FTA2 PF13095.6 KFX92292.1 - 6.2e-06 26.0 0.1 0.00069 19.3 0.0 2.2 2 0 0 2 2 2 1 Kinetochore Sim4 complex subunit FTA2 DAO PF01266.24 KFX92292.1 - 5.6e-05 22.9 0.0 0.0006 19.5 0.0 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 KFX92292.1 - 0.00014 21.2 0.2 0.33 10.2 0.1 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KFX92292.1 - 0.00089 18.4 0.0 0.0014 17.7 0.0 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_2 PF07992.14 KFX92292.1 - 0.0012 18.2 0.0 0.0054 16.0 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KFX92292.1 - 0.0017 18.6 0.2 0.0066 16.7 0.2 2.1 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 KFX92292.1 - 0.015 14.5 0.0 0.034 13.4 0.0 1.5 1 0 0 1 1 1 0 Thi4 family Peptidase_M3 PF01432.20 KFX92293.1 - 3.5e-118 395.8 0.0 2.4e-117 393.0 0.0 1.9 2 0 0 2 2 2 1 Peptidase family M3 Cupin_6 PF12852.7 KFX92293.1 - 0.009 15.7 0.0 0.017 14.9 0.0 1.3 1 0 0 1 1 1 1 Cupin Peptidase_M91 PF14891.6 KFX92293.1 - 0.13 12.6 0.0 0.31 11.4 0.0 1.6 1 0 0 1 1 1 0 Effector protein Baculo_PEP_C PF04513.12 KFX92293.1 - 0.53 10.3 4.6 1.6 8.8 2.2 2.3 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus adh_short PF00106.25 KFX92294.1 - 2e-41 141.6 0.1 2.5e-41 141.3 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KFX92294.1 - 8.8e-31 107.3 0.0 1.1e-30 107.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KFX92294.1 - 2.9e-07 30.6 0.0 4e-07 30.1 0.0 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 KFX92294.1 - 3.1e-05 24.0 0.1 4.8e-05 23.3 0.1 1.3 1 0 0 1 1 1 1 NAD(P)H-binding DUF1776 PF08643.10 KFX92294.1 - 0.00016 21.2 0.0 0.35 10.2 0.0 2.1 2 0 0 2 2 2 2 Fungal family of unknown function (DUF1776) NmrA PF05368.13 KFX92294.1 - 0.00021 20.9 0.3 0.00032 20.4 0.3 1.2 1 0 0 1 1 1 1 NmrA-like family DNA_pol_lambd_f PF10391.9 KFX92294.1 - 0.00041 20.1 0.0 0.00081 19.2 0.0 1.5 1 0 0 1 1 1 1 Fingers domain of DNA polymerase lambda Shikimate_DH PF01488.20 KFX92294.1 - 0.00075 19.6 0.1 0.0013 18.8 0.1 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase ADH_zinc_N PF00107.26 KFX92294.1 - 0.0013 18.7 0.1 0.0097 15.9 0.0 2.0 1 1 0 2 2 2 1 Zinc-binding dehydrogenase Epimerase PF01370.21 KFX92294.1 - 0.0019 17.7 0.2 0.01 15.3 0.1 1.9 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family TrkA_N PF02254.18 KFX92294.1 - 0.0053 17.0 0.2 0.0097 16.2 0.2 1.4 1 0 0 1 1 1 1 TrkA-N domain 2-Hacid_dh_C PF02826.19 KFX92294.1 - 0.0059 16.0 0.1 0.011 15.2 0.1 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ApbA PF02558.16 KFX92294.1 - 0.027 14.1 0.1 0.047 13.3 0.1 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA F420_oxidored PF03807.17 KFX92294.1 - 0.043 14.4 0.1 0.089 13.4 0.1 1.5 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent 3HCDH_N PF02737.18 KFX92294.1 - 0.075 12.9 0.1 0.14 12.0 0.1 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DREV PF05219.12 KFX92294.1 - 0.078 12.1 0.0 0.17 10.9 0.0 1.5 2 0 0 2 2 2 0 DREV methyltransferase PsiA PF06952.11 KFX92294.1 - 0.18 11.0 0.0 0.26 10.5 0.0 1.2 1 0 0 1 1 1 0 PsiA protein Zn_clus PF00172.18 KFX92295.1 - 0.00017 21.6 6.9 0.00028 20.9 6.9 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KFX92295.1 - 0.00036 19.6 2.2 0.0016 17.6 0.5 2.6 2 1 0 2 2 2 1 Fungal specific transcription factor domain MOSC PF03473.17 KFX92295.1 - 0.031 14.3 0.7 0.069 13.2 0.7 1.5 1 0 0 1 1 1 0 MOSC domain Sugar_tr PF00083.24 KFX92296.1 - 1.6e-107 360.2 17.2 2e-107 359.9 17.2 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KFX92296.1 - 1.2e-23 83.6 33.2 7.4e-21 74.4 26.4 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 KFX92296.1 - 0.00095 17.7 0.5 0.0024 16.4 0.5 1.6 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) TauD PF02668.16 KFX92297.1 - 1.6e-54 185.5 0.2 1.8e-54 185.3 0.2 1.0 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family ADH_N PF08240.12 KFX92298.1 - 1.7e-23 82.6 7.7 4.2e-23 81.3 7.7 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KFX92298.1 - 9.8e-19 67.6 2.2 1.8e-18 66.8 2.2 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KFX92298.1 - 9.2e-06 26.7 0.2 1.5e-05 26.0 0.2 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 KFX92298.1 - 0.053 13.0 1.0 0.084 12.4 1.0 1.3 1 1 0 1 1 1 0 Glucose dehydrogenase C-terminus Skp1_POZ PF03931.15 KFX92301.1 - 1.5e-11 44.3 1.8 3.2e-11 43.2 1.1 1.9 2 0 0 2 2 2 1 Skp1 family, tetramerisation domain Tox-MPTase3 PF15639.6 KFX92301.1 - 0.14 12.0 0.6 0.24 11.2 0.6 1.4 1 0 0 1 1 1 0 Metallopeptidase toxin 3 Mrr_N PF14338.6 KFX92301.1 - 0.16 12.1 0.0 0.36 11.0 0.0 1.6 1 0 0 1 1 1 0 Mrr N-terminal domain zf-BED PF02892.15 KFX92328.1 - 0.71 9.9 9.8 1.5 8.9 0.4 3.5 3 0 0 3 3 3 0 BED zinc finger zf-CHCC PF10276.9 KFX92328.1 - 3.9 7.6 7.7 8.9 6.5 0.3 3.1 3 0 0 3 3 3 0 Zinc-finger domain zf-C2H2_jaz PF12171.8 KFX92328.1 - 6.2 7.2 14.8 1.1 9.7 3.5 3.2 2 1 1 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-C2H2 PF00096.26 KFX92328.1 - 7.2 7.3 25.7 0.067 13.7 0.9 4.6 4 0 0 4 4 4 0 Zinc finger, C2H2 type Vfa1 PF08432.10 KFX92329.1 - 1.3e-56 191.8 20.9 1.5e-56 191.6 20.9 1.0 1 0 0 1 1 1 1 AAA-ATPase Vps4-associated protein 1 Dynactin_p62 PF05502.13 KFX92329.1 - 1.6e-05 23.9 5.7 1.8e-05 23.7 5.7 1.1 1 0 0 1 1 1 1 Dynactin p62 family CDC45 PF02724.14 KFX92329.1 - 0.0038 15.6 12.2 0.0038 15.6 12.2 1.0 1 0 0 1 1 1 1 CDC45-like protein MTBP_N PF14918.6 KFX92329.1 - 0.0064 16.0 2.7 0.007 15.9 2.2 1.3 1 1 0 1 1 1 1 MDM2-binding SRP-alpha_N PF04086.13 KFX92329.1 - 0.022 14.7 19.7 0.028 14.3 19.7 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal RR_TM4-6 PF06459.12 KFX92329.1 - 0.035 13.9 17.2 0.044 13.6 17.2 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Atrophin-1 PF03154.15 KFX92329.1 - 0.061 11.6 17.2 0.075 11.3 17.2 1.1 1 0 0 1 1 1 0 Atrophin-1 family SAPS PF04499.15 KFX92329.1 - 0.066 12.0 7.0 0.063 12.1 7.0 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein DUF913 PF06025.12 KFX92329.1 - 0.08 11.9 4.5 0.084 11.8 4.5 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) NPR3 PF03666.13 KFX92329.1 - 0.12 11.2 10.6 0.13 11.1 10.6 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 SID-1_RNA_chan PF13965.6 KFX92329.1 - 0.14 10.5 2.9 0.14 10.5 2.9 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 SpoIIIAH PF12685.7 KFX92329.1 - 0.14 11.9 11.8 0.18 11.6 11.8 1.1 1 0 0 1 1 1 0 SpoIIIAH-like protein DDHD PF02862.17 KFX92329.1 - 0.15 12.2 3.8 0.17 12.1 3.8 1.1 1 0 0 1 1 1 0 DDHD domain Tim54 PF11711.8 KFX92329.1 - 0.17 10.7 12.6 0.21 10.3 12.6 1.2 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Connexin PF00029.19 KFX92329.1 - 0.19 11.4 8.6 0.24 11.1 8.6 1.2 1 0 0 1 1 1 0 Connexin SLC12 PF03522.15 KFX92329.1 - 0.21 10.6 8.4 0.23 10.4 8.4 1.1 1 0 0 1 1 1 0 Solute carrier family 12 XRN_M PF17846.1 KFX92329.1 - 0.21 10.5 8.6 0.26 10.2 8.6 1.1 1 0 0 1 1 1 0 Xrn1 helical domain Borrelia_P83 PF05262.11 KFX92329.1 - 0.31 9.5 22.3 0.37 9.2 22.3 1.0 1 0 0 1 1 1 0 Borrelia P83/100 protein CPSF100_C PF13299.6 KFX92329.1 - 0.37 10.9 10.2 0.56 10.4 10.2 1.4 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal DUF3438 PF11920.8 KFX92329.1 - 0.54 9.5 7.1 0.62 9.3 7.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3438) DUF908 PF06012.12 KFX92329.1 - 0.88 8.9 5.2 1 8.7 5.2 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) Neur_chan_memb PF02932.16 KFX92329.1 - 0.96 9.5 4.3 0.99 9.4 4.3 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Peptidase_S49_N PF08496.10 KFX92329.1 - 0.97 9.5 17.6 1.7 8.7 17.6 1.5 1 0 0 1 1 1 0 Peptidase family S49 N-terminal PPL5 PF18168.1 KFX92329.1 - 0.99 8.6 12.3 1.2 8.4 12.3 1.1 1 0 0 1 1 1 0 Prim-pol family 5 Astro_capsid_p PF12226.8 KFX92329.1 - 1.1 8.4 9.2 1.4 8.0 9.2 1.1 1 0 0 1 1 1 0 Turkey astrovirus capsid protein SpoIIP PF07454.11 KFX92329.1 - 1.1 8.7 13.5 1.3 8.4 13.5 1.1 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) TP53IP5 PF15331.6 KFX92329.1 - 1.3 9.2 14.5 1.6 8.8 14.5 1.1 1 0 0 1 1 1 0 Cellular tumour antigen p53-inducible 5 Serinc PF03348.15 KFX92329.1 - 1.4 7.8 3.0 1.4 7.7 3.0 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) Rrn6 PF10214.9 KFX92329.1 - 1.4 7.3 10.4 1.6 7.1 10.4 1.0 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor RNA_pol_Rpc4 PF05132.14 KFX92329.1 - 1.7 9.1 16.0 0.04 14.4 9.5 1.7 2 0 0 2 2 1 0 RNA polymerase III RPC4 Trypan_PARP PF05887.11 KFX92329.1 - 1.7 8.6 9.8 2.7 7.9 9.8 1.4 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) CLN3 PF02487.17 KFX92329.1 - 2.7 6.9 3.5 3 6.8 3.5 1.1 1 0 0 1 1 1 0 CLN3 protein FAM176 PF14851.6 KFX92329.1 - 2.8 7.6 14.3 4.3 7.0 14.3 1.4 1 0 0 1 1 1 0 FAM176 family ATP11 PF06644.11 KFX92329.1 - 2.9 7.6 16.8 3.4 7.4 16.8 1.1 1 0 0 1 1 1 0 ATP11 protein GNAT_acetyltr_2 PF13718.6 KFX92329.1 - 3.3 7.1 7.0 4.4 6.6 7.0 1.2 1 0 0 1 1 1 0 GNAT acetyltransferase 2 Zip PF02535.22 KFX92329.1 - 3.3 6.8 8.1 4.1 6.5 8.1 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter TRAP_alpha PF03896.16 KFX92329.1 - 4.8 6.3 11.8 6.3 5.9 11.8 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Hid1 PF12722.7 KFX92329.1 - 4.9 5.1 11.4 5.9 4.9 11.4 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein MCM_bind PF09739.9 KFX92329.1 - 5.2 5.4 11.4 6.3 5.1 11.4 1.1 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor U79_P34 PF03064.16 KFX92329.1 - 5.4 6.3 28.0 7.4 5.9 28.0 1.2 1 0 0 1 1 1 0 HSV U79 / HCMV P34 PTPRCAP PF15713.5 KFX92329.1 - 6.1 7.1 16.2 8 6.7 16.2 1.2 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated GCD14 PF08704.10 KFX92329.1 - 6.3 6.4 6.9 8.6 5.9 6.9 1.2 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit Presenilin PF01080.17 KFX92329.1 - 7.1 5.3 14.6 8.5 5.0 14.6 1.1 1 0 0 1 1 1 0 Presenilin ALMT PF11744.8 KFX92329.1 - 7.3 5.3 8.6 8.4 5.1 8.6 1.0 1 0 0 1 1 1 0 Aluminium activated malate transporter Ureide_permease PF07168.11 KFX92329.1 - 9.6 4.8 8.9 12 4.5 8.9 1.1 1 0 0 1 1 1 0 Ureide permease Rtt106 PF08512.12 KFX92330.1 - 1.9e-30 105.1 0.0 4e-30 104.1 0.0 1.6 1 0 0 1 1 1 1 Histone chaperone Rttp106-like PH_18 PF18469.1 KFX92330.1 - 0.034 14.1 0.1 0.24 11.4 0.1 2.3 2 1 0 2 2 2 0 Pleckstrin homology domain MDD_C PF18376.1 KFX92331.1 - 3.5e-65 219.3 0.0 4.8e-65 218.8 0.0 1.2 1 0 0 1 1 1 1 Mevalonate 5-diphosphate decarboxylase C-terminal domain GHMP_kinases_N PF00288.26 KFX92331.1 - 2.9e-09 37.0 0.7 1.1e-08 35.2 0.7 2.1 2 0 0 2 2 2 1 GHMP kinases N terminal domain CRF1 PF10380.9 KFX92341.1 - 0.0029 17.9 0.8 0.0092 16.3 0.0 2.3 2 0 0 2 2 2 1 Transcription factor CRF1 Peptidase_S10 PF00450.22 KFX92343.1 - 7.7e-49 167.2 2.4 9.2e-49 167.0 2.4 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase zf-RING_2 PF13639.6 KFX92344.1 - 5.1e-06 26.7 4.3 5.1e-06 26.7 4.3 1.9 2 0 0 2 2 2 1 Ring finger domain Prok-RING_1 PF14446.6 KFX92344.1 - 0.0002 21.2 4.6 0.00039 20.3 1.7 2.3 2 0 0 2 2 2 1 Prokaryotic RING finger family 1 SWIM PF04434.17 KFX92344.1 - 0.004 16.8 0.1 0.0084 15.8 0.1 1.5 1 0 0 1 1 1 1 SWIM zinc finger zf-ANAPC11 PF12861.7 KFX92344.1 - 0.011 15.8 1.7 0.011 15.8 1.7 2.0 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.6 KFX92344.1 - 0.074 13.1 2.5 0.17 12.0 2.5 1.6 1 0 0 1 1 1 0 RING-type zinc-finger PHD PF00628.29 KFX92344.1 - 0.83 9.6 5.6 1.8 8.5 5.6 1.6 1 0 0 1 1 1 0 PHD-finger C1_1 PF00130.22 KFX92344.1 - 1.3 9.0 6.5 0.75 9.7 2.3 2.3 1 1 1 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-C3HC4_2 PF13923.6 KFX92344.1 - 2.3 8.1 6.2 0.19 11.6 0.7 2.0 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) SCRL PF06876.12 KFX92344.1 - 6.3 7.0 9.1 0.99 9.6 2.1 2.4 2 0 0 2 2 2 0 Plant self-incompatibility response (SCRL) protein zf-rbx1 PF12678.7 KFX92344.1 - 7.4 7.0 7.8 0.58 10.5 2.6 1.9 2 0 0 2 2 2 0 RING-H2 zinc finger domain Tcp11 PF05794.13 KFX92345.1 - 2.5e-68 231.2 0.0 3.6e-68 230.7 0.0 1.1 1 0 0 1 1 1 1 T-complex protein 11 Aa_trans PF01490.18 KFX92346.1 - 3.3e-23 82.1 6.4 4.5e-23 81.6 6.4 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 KFX92346.1 - 0.19 10.7 8.1 0.25 10.3 8.1 1.1 1 0 0 1 1 1 0 Tryptophan/tyrosine permease family HEAT_EZ PF13513.6 KFX92348.1 - 1.9e-05 25.0 0.5 0.12 12.9 0.0 3.6 3 0 0 3 3 3 2 HEAT-like repeat HEAT_2 PF13646.6 KFX92348.1 - 2.5e-05 24.6 1.7 0.012 16.0 0.1 2.2 2 1 1 3 3 3 2 HEAT repeats HEAT PF02985.22 KFX92348.1 - 0.00095 19.2 0.1 0.0089 16.2 0.0 2.7 2 0 0 2 2 2 1 HEAT repeat Arm PF00514.23 KFX92348.1 - 0.064 13.3 0.2 15 5.8 0.0 2.8 2 0 0 2 2 2 0 Armadillo/beta-catenin-like repeat Actin PF00022.19 KFX92350.1 - 5.8e-150 499.4 0.0 2.3e-149 497.5 0.0 1.7 1 1 0 1 1 1 1 Actin TAF6_C PF07571.13 KFX92351.1 - 1.5e-30 105.4 0.0 2.1e-29 101.7 0.0 2.5 2 0 0 2 2 2 1 TAF6 C-terminal HEAT repeat domain TAF PF02969.17 KFX92351.1 - 4.1e-21 74.9 0.1 8.9e-21 73.8 0.1 1.6 1 0 0 1 1 1 1 TATA box binding protein associated factor (TAF) Adaptin_N PF01602.20 KFX92351.1 - 0.053 12.1 1.9 0.04 12.5 0.6 1.4 2 0 0 2 2 2 0 Adaptin N terminal region Thymidylate_kin PF02223.17 KFX92352.1 - 3.9e-49 166.9 0.0 4.5e-49 166.6 0.0 1.0 1 0 0 1 1 1 1 Thymidylate kinase AAA_28 PF13521.6 KFX92352.1 - 2.5e-07 31.1 0.0 3.5e-07 30.6 0.0 1.2 1 0 0 1 1 1 1 AAA domain PRK PF00485.18 KFX92352.1 - 0.0025 17.6 0.0 0.0093 15.7 0.0 1.8 2 0 0 2 2 2 1 Phosphoribulokinase / Uridine kinase family KTI12 PF08433.10 KFX92352.1 - 0.0089 15.5 0.9 0.018 14.5 0.1 1.9 2 1 0 2 2 2 1 Chromatin associated protein KTI12 dNK PF01712.19 KFX92352.1 - 0.011 15.6 0.1 0.087 12.7 0.1 2.0 1 1 0 1 1 1 0 Deoxynucleoside kinase DUF2235 PF09994.9 KFX92352.1 - 0.018 14.4 0.1 0.79 9.0 0.0 2.1 2 0 0 2 2 2 0 Uncharacterized alpha/beta hydrolase domain (DUF2235) SKI PF01202.22 KFX92352.1 - 0.1 12.7 0.0 0.18 11.9 0.0 1.4 1 0 0 1 1 1 0 Shikimate kinase GTP_cyclohydroI PF01227.22 KFX92353.1 - 3.8e-73 244.7 0.1 4.9e-73 244.4 0.1 1.1 1 0 0 1 1 1 1 GTP cyclohydrolase I QueF PF14489.6 KFX92353.1 - 0.018 15.2 0.0 0.035 14.2 0.0 1.4 1 0 0 1 1 1 0 QueF-like protein DUF4710 PF15828.5 KFX92353.1 - 0.17 12.1 1.5 0.83 9.8 1.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4710) EamA PF00892.20 KFX92355.1 - 4.3e-09 36.7 5.9 7e-09 36.0 5.9 1.4 1 0 0 1 1 1 1 EamA-like transporter family Zn_clus PF00172.18 KFX92355.1 - 9.4e-08 32.1 9.0 1.8e-07 31.2 9.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 KFX92355.1 - 4.8e-06 25.6 0.2 2.8e-05 23.1 0.0 2.0 2 0 0 2 2 2 1 Fungal specific transcription factor domain PSI_integrin PF17205.3 KFX92355.1 - 0.013 15.3 2.9 0.028 14.2 2.9 1.5 1 0 0 1 1 1 0 Integrin plexin domain Aldedh PF00171.22 KFX92356.1 - 2.5e-124 415.3 0.6 3e-124 415.0 0.6 1.1 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.11 KFX92356.1 - 0.056 12.9 0.0 0.13 11.7 0.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1487) MFS_1 PF07690.16 KFX92357.1 - 7.2e-15 54.8 45.3 7.2e-15 54.8 45.3 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily DUF4383 PF14325.6 KFX92357.1 - 0.0043 17.3 2.7 0.0043 17.3 2.7 3.6 4 0 0 4 4 4 2 Domain of unknown function (DUF4383) UPF0093 PF03653.13 KFX92357.1 - 0.0058 16.9 2.3 0.017 15.4 2.3 1.7 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0093) SPC22 PF04573.12 KFX92358.1 - 4e-30 104.6 0.0 8.2e-22 77.5 0.0 2.2 2 0 0 2 2 2 2 Signal peptidase subunit DUF4588 PF15251.6 KFX92361.1 - 0.034 13.9 3.0 0.059 13.1 3.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4588) HypA PF01155.19 KFX92361.1 - 3.5 7.7 18.9 0.83 9.7 2.7 3.3 3 0 0 3 3 3 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA DUF1524 PF07510.11 KFX92365.1 - 1.8e-09 37.6 0.0 2.2e-09 37.3 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1524) HNH_4 PF13395.6 KFX92365.1 - 0.067 13.1 0.5 0.23 11.4 0.5 1.8 1 1 0 1 1 1 0 HNH endonuclease Acyl-CoA_dh_1 PF00441.24 KFX92366.1 - 1.3e-25 90.3 0.4 2.6e-25 89.4 0.4 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 KFX92366.1 - 3.4e-20 72.1 0.0 8e-20 70.8 0.0 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain MMR_HSR1 PF01926.23 KFX92366.1 - 3.2e-16 59.4 0.2 7.9e-15 54.9 0.0 2.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase Acyl-CoA_dh_2 PF08028.11 KFX92366.1 - 3.7e-13 49.9 0.5 9.8e-13 48.5 0.5 1.8 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 KFX92366.1 - 4.1e-11 43.5 0.3 1.1e-10 42.1 0.0 2.0 2 0 0 2 2 1 1 Acyl-CoA dehydrogenase, N-terminal domain FeoB_N PF02421.18 KFX92366.1 - 1.8e-07 30.8 0.3 9.4e-06 25.2 0.1 2.4 2 0 0 2 2 2 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 KFX92366.1 - 2e-05 24.6 0.4 0.002 18.1 0.0 2.7 3 0 0 3 3 3 1 RsgA GTPase MTHFR PF02219.17 KFX92366.1 - 0.00022 20.7 0.0 0.29 10.4 0.0 2.3 1 1 1 2 2 2 2 Methylenetetrahydrofolate reductase AIG1 PF04548.16 KFX92366.1 - 0.013 14.8 0.1 0.027 13.8 0.1 1.5 1 0 0 1 1 1 0 AIG1 family Dynamin_N PF00350.23 KFX92366.1 - 0.022 14.8 4.2 0.25 11.4 0.1 3.2 4 0 0 4 4 4 0 Dynamin family DUF5523 PF17661.1 KFX92366.1 - 0.052 13.2 8.7 0.12 12.0 8.7 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5523) Astro_capsid_p PF12226.8 KFX92366.1 - 3.4 6.7 7.4 6.5 5.8 7.4 1.3 1 0 0 1 1 1 0 Turkey astrovirus capsid protein LTV PF04180.14 KFX92367.1 - 8.8e-128 427.3 18.3 1.1e-127 427.0 18.3 1.0 1 0 0 1 1 1 1 Low temperature viability protein GST_N_2 PF13409.6 KFX92368.1 - 1.5e-06 28.4 0.0 2.6e-06 27.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 KFX92368.1 - 7.1e-06 26.4 0.0 1.7e-05 25.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 KFX92368.1 - 0.00027 21.1 0.0 0.00054 20.1 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 KFX92368.1 - 0.00035 20.5 0.0 0.00097 19.1 0.0 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 KFX92368.1 - 0.0033 17.6 0.0 0.007 16.6 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain DBD_Tnp_Hermes PF10683.9 KFX92368.1 - 0.086 12.5 0.0 0.19 11.4 0.0 1.6 1 0 0 1 1 1 0 Hermes transposase DNA-binding domain Spo12 PF05032.12 KFX92369.1 - 9.4e-18 63.8 2.3 2.2e-17 62.7 1.5 2.0 2 0 0 2 2 2 1 Spo12 family MMR_HSR1_Xtn PF16897.5 KFX92370.1 - 3.6e-33 113.7 1.3 2.2e-32 111.2 0.4 2.3 2 0 0 2 2 2 1 C-terminal region of MMR_HSR1 domain MMR_HSR1 PF01926.23 KFX92370.1 - 6.3e-21 74.6 0.0 1.3e-20 73.6 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase TGS PF02824.21 KFX92370.1 - 1.1e-20 73.5 0.2 2.4e-20 72.3 0.0 1.7 2 0 0 2 2 2 1 TGS domain FeoB_N PF02421.18 KFX92370.1 - 1.3e-13 50.8 0.0 2.1e-13 50.1 0.0 1.3 1 0 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.23 KFX92370.1 - 9.6e-05 22.5 0.3 0.19 11.7 0.0 2.4 1 1 1 2 2 2 2 Dynamin family MCM PF00493.23 KFX92370.1 - 0.066 12.3 0.1 0.26 10.4 0.0 1.8 2 0 0 2 2 2 0 MCM P-loop domain MeaB PF03308.16 KFX92370.1 - 0.092 11.7 0.1 0.2 10.6 0.1 1.5 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AIG1 PF04548.16 KFX92370.1 - 0.12 11.7 0.0 0.19 11.0 0.0 1.3 1 0 0 1 1 1 0 AIG1 family Pro_isomerase PF00160.21 KFX92371.1 - 9.8e-46 155.9 0.3 1.8e-45 155.0 0.3 1.4 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Ribosomal_S13 PF00416.22 KFX92372.1 - 3.4e-19 69.5 0.1 2.6e-17 63.4 0.1 2.0 1 1 0 1 1 1 1 Ribosomal protein S13/S18 DLH PF01738.18 KFX92374.1 - 6.5e-19 68.4 0.0 7.7e-19 68.1 0.0 1.0 1 0 0 1 1 1 1 Dienelactone hydrolase family Peptidase_S9 PF00326.21 KFX92374.1 - 0.0036 16.8 0.0 0.024 14.1 0.0 1.9 2 0 0 2 2 2 1 Prolyl oligopeptidase family Peptidase_S15 PF02129.18 KFX92374.1 - 0.0042 16.7 0.0 0.0077 15.9 0.0 1.3 1 1 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_6 PF12697.7 KFX92374.1 - 0.01 16.5 3.0 0.043 14.4 1.5 1.7 1 1 1 2 2 2 0 Alpha/beta hydrolase family AXE1 PF05448.12 KFX92374.1 - 0.23 10.1 0.0 0.33 9.6 0.0 1.2 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) RCDG1 PF15725.5 KFX92387.1 - 0.022 15.1 3.4 0.036 14.5 3.4 1.3 1 0 0 1 1 1 0 Renal cancer differentiation gene 1 protein PhyH PF05721.13 KFX92390.1 - 8.5e-36 124.2 0.0 1.2e-35 123.7 0.0 1.2 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) 2OG-FeII_Oxy_5 PF13759.6 KFX92390.1 - 0.06 13.8 0.0 0.14 12.5 0.0 1.6 1 0 0 1 1 1 0 Putative 2OG-Fe(II) oxygenase Toxin_35 PF10530.9 KFX92394.1 - 0.0031 17.4 1.1 0.005 16.8 1.1 1.3 1 0 0 1 1 1 1 Toxin with inhibitor cystine knot ICK or Knottin scaffold F-box-like PF12937.7 KFX92395.1 - 0.096 12.6 3.8 0.19 11.6 2.0 2.5 2 0 0 2 2 2 0 F-box-like F-box PF00646.33 KFX92395.1 - 0.14 12.1 4.0 0.14 12.1 1.6 2.4 2 0 0 2 2 2 0 F-box domain GATA PF00320.27 KFX92414.1 - 1.5e-16 59.7 2.7 8.4e-16 57.3 2.5 2.2 2 0 0 2 2 2 1 GATA zinc finger DUF1752 PF08550.10 KFX92414.1 - 6.3e-13 48.3 2.8 1.2e-12 47.4 2.8 1.5 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) Lipase_GDSL_2 PF13472.6 KFX92424.1 - 0.0013 19.2 0.0 0.0019 18.6 0.0 1.4 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family F-box PF00646.33 KFX92425.1 - 0.0046 16.8 0.0 0.0062 16.4 0.0 1.2 1 0 0 1 1 1 1 F-box domain ERG4_ERG24 PF01222.17 KFX92426.1 - 3e-167 556.8 5.9 3.6e-167 556.5 5.9 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF1295 PF06966.12 KFX92426.1 - 0.00033 20.3 0.1 0.001 18.7 0.1 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) PhyH PF05721.13 KFX92428.1 - 4e-29 102.4 0.1 5.3e-29 102.0 0.1 1.1 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) 2OG-FeII_Oxy_5 PF13759.6 KFX92428.1 - 0.00057 20.3 0.1 0.0015 18.9 0.1 1.8 1 1 0 1 1 1 1 Putative 2OG-Fe(II) oxygenase 2OG-FeII_Oxy_3 PF13640.6 KFX92428.1 - 0.076 13.9 0.3 0.24 12.3 0.1 1.9 1 1 1 2 2 2 0 2OG-Fe(II) oxygenase superfamily DUF3836 PF12930.7 KFX92428.1 - 0.15 11.8 0.4 0.25 11.1 0.4 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF3836) Zn_clus PF00172.18 KFX92429.1 - 8.1e-09 35.5 9.7 1.3e-08 34.8 9.7 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain BHD_2 PF10404.9 KFX92429.1 - 0.11 13.4 0.0 23 6.0 0.0 2.4 2 0 0 2 2 2 0 Rad4 beta-hairpin domain 2 Tub_N PF16322.5 KFX92436.1 - 1.1 9.6 10.8 1.5 9.2 10.8 1.3 1 0 0 1 1 1 0 Tubby N-terminal Ribosomal_60s PF00428.19 KFX92436.1 - 3.8 8.2 15.2 0.94 10.1 5.6 2.7 2 0 0 2 2 2 0 60s Acidic ribosomal protein ABA_GPCR PF12430.8 KFX92437.1 - 1.7e-55 187.6 0.0 2.2e-55 187.2 0.0 1.2 1 0 0 1 1 1 1 Abscisic acid G-protein coupled receptor GPHR_N PF12537.8 KFX92437.1 - 3e-24 84.9 0.0 8.8e-24 83.4 0.0 1.8 1 0 0 1 1 1 1 The Golgi pH Regulator (GPHR) Family N-terminal Pkinase PF00069.25 KFX92439.1 - 7.9e-66 222.1 0.0 1.3e-65 221.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFX92439.1 - 2.2e-51 174.6 0.0 4e-51 173.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Ras_bdg_2 PF14847.6 KFX92439.1 - 2.8e-29 101.4 0.0 5.4e-29 100.5 0.0 1.5 1 0 0 1 1 1 1 Ras-binding domain of Byr2 SAM_1 PF00536.30 KFX92439.1 - 6.1e-16 58.6 0.2 1.3e-15 57.6 0.2 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 KFX92439.1 - 2.6e-13 49.8 0.1 5.2e-13 48.9 0.1 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) RA PF00788.23 KFX92439.1 - 1.1e-09 38.8 0.1 2.1e-09 37.9 0.1 1.5 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain Kinase-like PF14531.6 KFX92439.1 - 2.3e-08 33.7 0.0 1.1e-06 28.2 0.0 2.4 2 0 0 2 2 2 1 Kinase-like SAM_PNT PF02198.16 KFX92439.1 - 0.0012 18.7 0.0 0.0023 17.9 0.0 1.4 1 0 0 1 1 1 1 Sterile alpha motif (SAM)/Pointed domain Pkinase_fungal PF17667.1 KFX92439.1 - 0.07 11.9 0.0 0.16 10.7 0.0 1.5 1 0 0 1 1 1 0 Fungal protein kinase SAM_4 PF18017.1 KFX92439.1 - 0.081 12.9 0.1 0.19 11.7 0.1 1.5 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) Pep3_Vps18 PF05131.14 KFX92441.1 - 3.3e-46 156.8 0.0 1.1e-45 155.2 0.0 1.9 2 0 0 2 2 2 1 Pep3/Vps18/deep orange family Clathrin PF00637.20 KFX92441.1 - 1.2e-06 28.4 2.2 0.00012 21.9 0.0 3.5 3 1 0 3 3 3 1 Region in Clathrin and VPS Zn_ribbon_17 PF17120.5 KFX92441.1 - 0.00041 19.9 0.1 0.00099 18.7 0.1 1.6 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-RING_5 PF14634.6 KFX92441.1 - 0.00092 19.1 0.4 0.0023 17.9 0.4 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 KFX92441.1 - 0.0012 18.7 0.6 0.0036 17.1 0.6 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) DUF2175 PF09943.9 KFX92441.1 - 0.0014 18.8 0.5 0.039 14.3 0.0 2.4 2 0 0 2 2 2 1 Uncharacterized protein conserved in archaea (DUF2175) zf-RING_2 PF13639.6 KFX92441.1 - 0.0084 16.4 0.5 0.026 14.8 0.5 1.8 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 KFX92441.1 - 0.013 15.2 4.0 0.013 15.2 4.0 1.9 2 0 0 2 2 2 0 RING-like zinc finger Vps39_2 PF10367.9 KFX92441.1 - 0.03 14.8 0.0 0.071 13.6 0.0 1.6 1 0 0 1 1 1 0 Vacuolar sorting protein 39 domain 2 Glyco_hydro81C PF17652.1 KFX92441.1 - 0.036 13.3 0.0 0.057 12.6 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 81 C-terminal domain zf-RING_UBOX PF13445.6 KFX92441.1 - 0.044 13.8 0.5 0.099 12.7 0.5 1.6 1 0 0 1 1 1 0 RING-type zinc-finger zf-rbx1 PF12678.7 KFX92441.1 - 0.069 13.5 0.3 0.19 12.0 0.3 1.7 1 0 0 1 1 1 0 RING-H2 zinc finger domain dCMP_cyt_deam_2 PF08211.12 KFX92441.1 - 0.11 12.7 0.0 13 6.0 0.0 2.5 2 0 0 2 2 2 0 Cytidine and deoxycytidylate deaminase zinc-binding region zf-C3HC4 PF00097.25 KFX92441.1 - 0.63 10.0 2.6 0.43 10.5 0.2 2.0 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3H2C3 PF17122.5 KFX92441.1 - 7.1 6.8 6.5 1.2 9.2 2.4 1.9 2 0 0 2 2 2 0 Zinc-finger AIRS_C PF02769.22 KFX92442.1 - 9.6e-36 123.3 0.1 1.5e-35 122.6 0.1 1.3 1 0 0 1 1 1 1 AIR synthase related protein, C-terminal domain AIRS PF00586.24 KFX92442.1 - 4.5e-15 56.1 1.8 9e-15 55.1 1.8 1.5 1 0 0 1 1 1 1 AIR synthase related protein, N-terminal domain DHDPS PF00701.22 KFX92443.1 - 5.8e-37 127.0 0.0 7.4e-37 126.6 0.0 1.1 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family MR_MLE_C PF13378.6 KFX92444.1 - 6e-58 196.0 0.0 8.8e-58 195.4 0.0 1.2 1 0 0 1 1 1 1 Enolase C-terminal domain-like MAAL_C PF07476.11 KFX92444.1 - 0.0019 17.4 0.0 0.0035 16.6 0.0 1.4 1 0 0 1 1 1 1 Methylaspartate ammonia-lyase C-terminus MR_MLE_N PF02746.16 KFX92444.1 - 0.0025 18.0 0.2 0.0077 16.4 0.0 1.8 2 0 0 2 2 2 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain OMPdecase PF00215.24 KFX92445.1 - 1.2e-89 299.8 0.1 1.7e-89 299.3 0.1 1.2 1 0 0 1 1 1 1 Orotidine 5'-phosphate decarboxylase / HUMPS family Na_Ca_ex PF01699.24 KFX92446.1 - 1.2e-19 70.8 34.8 8.2e-15 55.1 14.1 4.1 4 2 0 4 4 4 2 Sodium/calcium exchanger protein YccF PF03733.13 KFX92446.1 - 1e-15 58.2 12.9 1e-15 58.2 12.9 4.4 5 0 0 5 5 5 1 Inner membrane component domain AAA PF00004.29 KFX92447.1 - 8e-44 149.3 0.0 1.3e-43 148.6 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KFX92447.1 - 6.5e-14 51.5 0.0 1.3e-13 50.5 0.0 1.5 1 0 0 1 1 1 1 AAA+ lid domain AAA_5 PF07728.14 KFX92447.1 - 1.1e-07 31.9 0.0 2.7e-07 30.7 0.0 1.6 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 KFX92447.1 - 1.4e-07 31.8 0.0 2.6e-07 30.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 KFX92447.1 - 2e-06 28.3 0.0 0.00011 22.6 0.0 2.8 2 1 0 3 3 3 1 AAA ATPase domain Prot_ATP_ID_OB PF16450.5 KFX92447.1 - 1.7e-05 24.7 2.4 4.5e-05 23.3 2.4 1.8 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_22 PF13401.6 KFX92447.1 - 2.7e-05 24.5 0.2 0.006 16.9 0.2 2.4 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.12 KFX92447.1 - 5.6e-05 22.9 0.0 0.00011 22.0 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain TIP49 PF06068.13 KFX92447.1 - 0.00098 18.4 0.0 0.002 17.4 0.0 1.5 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_33 PF13671.6 KFX92447.1 - 0.0015 18.7 0.0 0.0029 17.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 KFX92447.1 - 0.0028 17.4 0.0 0.0052 16.5 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_18 PF13238.6 KFX92447.1 - 0.0034 17.9 0.0 0.019 15.5 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_3 PF07726.11 KFX92447.1 - 0.0035 17.2 0.0 0.01 15.7 0.0 1.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) ATPase PF06745.13 KFX92447.1 - 0.0074 15.7 0.0 0.019 14.3 0.0 1.7 1 0 0 1 1 1 1 KaiC Mg_chelatase PF01078.21 KFX92447.1 - 0.008 15.6 0.0 0.017 14.5 0.0 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI Prot_ATP_OB_N PF17758.1 KFX92447.1 - 0.0095 15.6 0.1 0.036 13.7 0.1 2.0 1 1 0 1 1 1 1 Proteasomal ATPase OB N-terminal domain TsaE PF02367.17 KFX92447.1 - 0.011 15.8 0.0 0.02 14.9 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_28 PF13521.6 KFX92447.1 - 0.011 15.9 0.0 0.02 15.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain DUF815 PF05673.13 KFX92447.1 - 0.021 14.0 0.0 0.038 13.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Sigma54_activat PF00158.26 KFX92447.1 - 0.022 14.4 0.0 0.097 12.4 0.0 2.0 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_7 PF12775.7 KFX92447.1 - 0.027 14.0 0.0 0.044 13.3 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_24 PF13479.6 KFX92447.1 - 0.032 14.0 0.0 0.1 12.3 0.0 1.8 3 0 0 3 3 2 0 AAA domain PhoH PF02562.16 KFX92447.1 - 0.034 13.6 0.0 0.14 11.6 0.0 1.9 2 0 0 2 2 2 0 PhoH-like protein AAA_14 PF13173.6 KFX92447.1 - 0.035 14.1 0.0 0.06 13.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 KFX92447.1 - 0.036 14.4 0.0 0.064 13.6 0.0 1.4 1 0 0 1 1 1 0 RNA helicase AAA_25 PF13481.6 KFX92447.1 - 0.05 13.2 0.1 0.17 11.5 0.0 1.8 2 0 0 2 2 2 0 AAA domain HR1 PF02185.16 KFX92447.1 - 0.052 13.7 0.7 0.13 12.4 0.7 1.6 1 0 0 1 1 1 0 Hr1 repeat Parvo_NS1 PF01057.17 KFX92447.1 - 0.059 12.4 0.0 0.1 11.7 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Zeta_toxin PF06414.12 KFX92447.1 - 0.11 11.8 0.0 0.19 11.0 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin DUF2072 PF09845.9 KFX92447.1 - 0.17 12.1 0.1 0.33 11.2 0.1 1.4 1 0 0 1 1 1 0 Zn-ribbon containing protein Y_phosphatase PF00102.27 KFX92448.1 - 6e-58 196.2 0.0 7.5e-57 192.6 0.0 2.4 1 1 0 1 1 1 1 Protein-tyrosine phosphatase Rhodanese PF00581.20 KFX92448.1 - 1.8e-12 47.7 0.0 4.2e-12 46.5 0.0 1.7 1 0 0 1 1 1 1 Rhodanese-like domain Y_phosphatase3 PF13350.6 KFX92448.1 - 0.025 14.6 0.1 0.084 12.8 0.1 1.8 1 1 0 1 1 1 0 Tyrosine phosphatase family DSPc PF00782.20 KFX92448.1 - 0.13 12.0 0.1 0.3 10.9 0.1 1.5 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain UCH PF00443.29 KFX92449.1 - 1.4e-18 67.3 0.0 3.3e-18 66.1 0.0 1.6 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KFX92449.1 - 5.9e-13 49.1 0.2 6.7e-12 45.6 0.2 2.0 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Zn-ribbon_8 PF09723.10 KFX92449.1 - 0.03 14.4 0.3 6.6 6.9 0.1 2.8 2 0 0 2 2 2 0 Zinc ribbon domain DNA_RNApol_7kD PF03604.13 KFX92449.1 - 0.064 12.9 1.2 2.9 7.7 0.0 2.6 2 0 0 2 2 2 0 DNA directed RNA polymerase, 7 kDa subunit GET2 PF08690.10 KFX92449.1 - 0.16 11.6 0.0 0.32 10.6 0.0 1.4 1 0 0 1 1 1 0 GET complex subunit GET2 Methyltransf_11 PF08241.12 KFX92450.1 - 1.4e-08 35.3 0.0 2.2e-08 34.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KFX92450.1 - 3.9e-07 30.1 0.0 5e-07 29.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KFX92450.1 - 5.3e-07 30.3 0.0 8.4e-07 29.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KFX92450.1 - 5.9e-06 26.9 0.0 1.1e-05 26.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KFX92450.1 - 0.0039 17.0 0.0 0.0051 16.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MetW PF07021.12 KFX92450.1 - 0.13 11.8 0.1 0.19 11.3 0.1 1.4 1 1 0 1 1 1 0 Methionine biosynthesis protein MetW CMAS PF02353.20 KFX92450.1 - 0.15 11.3 0.0 0.22 10.8 0.0 1.3 1 1 0 1 1 1 0 Mycolic acid cyclopropane synthetase TehB PF03848.14 KFX92450.1 - 0.17 11.3 0.0 0.44 9.9 0.0 1.7 1 1 0 1 1 1 0 Tellurite resistance protein TehB Myb_DNA-binding PF00249.31 KFX92451.1 - 8.3e-14 51.5 4.0 4.8e-10 39.5 0.0 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KFX92451.1 - 7.7e-06 26.1 2.0 0.012 15.9 0.1 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain NDUF_B8 PF05821.11 KFX92454.1 - 4.2e-06 26.7 0.1 5.6e-06 26.3 0.1 1.2 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase ASHI subunit (CI-ASHI or NDUFB8) DUF2205 PF10224.9 KFX92456.1 - 5.8e-37 125.5 2.3 8.7e-37 125.0 2.3 1.3 1 0 0 1 1 1 1 Short coiled-coil protein Cbl_N PF02262.16 KFX92456.1 - 0.0071 16.4 0.1 0.01 15.8 0.1 1.2 1 0 0 1 1 1 1 CBL proto-oncogene N-terminal domain 1 Spectrin PF00435.21 KFX92456.1 - 0.026 15.0 1.3 0.041 14.4 1.3 1.2 1 0 0 1 1 1 0 Spectrin repeat DUF4208 PF13907.6 KFX92456.1 - 0.048 14.1 0.6 0.067 13.6 0.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4208) SapC PF07277.11 KFX92456.1 - 0.07 12.7 0.1 0.093 12.3 0.1 1.1 1 0 0 1 1 1 0 SapC DUF908 PF06012.12 KFX92456.1 - 2.5 7.4 8.5 3 7.2 8.5 1.2 1 1 0 1 1 1 0 Domain of Unknown Function (DUF908) PIEZO PF15917.5 KFX92458.1 - 0.002 17.7 9.3 0.0034 16.9 9.3 1.4 1 0 0 1 1 1 1 Piezo CAF-1_p150 PF11600.8 KFX92458.1 - 0.0025 17.6 30.1 0.0029 17.3 30.1 1.2 1 0 0 1 1 1 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal Neur_chan_memb PF02932.16 KFX92458.1 - 0.018 15.1 3.4 0.02 15.0 3.4 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region CDC45 PF02724.14 KFX92458.1 - 0.057 11.7 10.8 0.055 11.8 10.8 1.1 1 0 0 1 1 1 0 CDC45-like protein RR_TM4-6 PF06459.12 KFX92458.1 - 0.1 12.4 14.8 0.12 12.2 14.8 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DDHD PF02862.17 KFX92458.1 - 0.13 12.4 1.8 0.14 12.3 1.8 1.1 1 0 0 1 1 1 0 DDHD domain Med19 PF10278.9 KFX92458.1 - 0.15 12.0 19.5 0.21 11.5 19.5 1.3 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 Paf1 PF03985.13 KFX92458.1 - 0.3 10.0 15.7 0.33 9.9 15.7 1.2 1 0 0 1 1 1 0 Paf1 CTU2 PF10288.9 KFX92458.1 - 0.34 11.2 8.8 0.47 10.7 8.8 1.4 1 0 0 1 1 1 0 Cytoplasmic tRNA 2-thiolation protein 2 TERB2 PF15101.6 KFX92458.1 - 0.41 10.7 5.9 0.48 10.4 5.9 1.2 1 0 0 1 1 1 0 Telomere-associated protein TERB2 SpoIIP PF07454.11 KFX92458.1 - 0.59 9.5 7.9 0.68 9.3 7.9 1.1 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) NPR3 PF03666.13 KFX92458.1 - 0.82 8.4 12.2 0.97 8.2 12.2 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 AAA_23 PF13476.6 KFX92458.1 - 0.87 10.0 12.1 1.1 9.7 12.1 1.1 1 0 0 1 1 1 0 AAA domain DUF4407 PF14362.6 KFX92458.1 - 0.93 8.8 8.5 1.1 8.6 8.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Presenilin PF01080.17 KFX92458.1 - 1 8.0 10.5 1.1 8.0 10.5 1.1 1 0 0 1 1 1 0 Presenilin DUF2828 PF11443.8 KFX92458.1 - 1.2 7.1 11.5 1.4 6.9 11.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) AAA_11 PF13086.6 KFX92458.1 - 1.3 8.8 10.3 1.4 8.6 10.3 1.1 1 0 0 1 1 1 0 AAA domain DUF4746 PF15928.5 KFX92458.1 - 1.3 8.4 11.0 1.4 8.2 11.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) MDM10 PF12519.8 KFX92458.1 - 1.9 7.3 6.9 1.9 7.3 6.9 1.1 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 NARP1 PF12569.8 KFX92458.1 - 2.8 6.7 20.6 3.6 6.4 20.6 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Sec62 PF03839.16 KFX92458.1 - 3.4 7.1 9.7 4.2 6.8 9.7 1.3 1 0 0 1 1 1 0 Translocation protein Sec62 MAJIN PF15077.6 KFX92458.1 - 3.7 7.3 9.6 4.6 7.0 9.6 1.2 1 0 0 1 1 1 0 Membrane-anchored junction protein DUF853 PF05872.12 KFX92458.1 - 3.9 6.0 5.4 4.6 5.7 5.4 1.0 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) eIF-3_zeta PF05091.12 KFX92458.1 - 4 6.3 12.9 4.6 6.1 12.9 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Connexin PF00029.19 KFX92458.1 - 4.2 7.1 11.8 5.8 6.6 11.8 1.2 1 0 0 1 1 1 0 Connexin ALMT PF11744.8 KFX92458.1 - 6.9 5.4 6.0 7.2 5.3 6.0 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter V_ATPase_I PF01496.19 KFX92458.1 - 8.6 4.1 10.4 11 3.8 10.4 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Opi1 PF08618.10 KFX92459.1 - 5.3e-40 138.0 22.6 6.8e-31 107.9 4.0 3.7 3 1 1 4 4 4 3 Transcription factor Opi1 Exc PF07825.11 KFX92459.1 - 0.0049 16.8 0.6 0.042 13.8 0.0 2.5 2 0 0 2 2 2 1 Excisionase-like protein DUF4149 PF13664.6 KFX92460.1 - 0.082 13.2 0.7 11 6.4 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4149) Ferric_reduct PF01794.19 KFX92460.1 - 1.5 8.9 6.7 1.6 8.8 1.2 2.5 2 0 0 2 2 2 0 Ferric reductase like transmembrane component Cys_Met_Meta_PP PF01053.20 KFX92461.1 - 2.6e-55 187.5 0.0 4e-54 183.6 0.0 2.3 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DUF4131 PF13567.6 KFX92461.1 - 0.005 16.5 0.0 0.097 12.3 0.0 2.6 2 1 0 2 2 2 1 Domain of unknown function (DUF4131) Aminotran_5 PF00266.19 KFX92461.1 - 0.068 12.1 0.0 0.11 11.4 0.0 1.3 1 0 0 1 1 1 0 Aminotransferase class-V HATPase_c_3 PF13589.6 KFX92462.1 - 7e-16 58.3 0.1 1.6e-15 57.1 0.1 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DNA_mis_repair PF01119.19 KFX92462.1 - 2.2e-10 40.3 0.0 4.5e-10 39.2 0.0 1.6 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain HATPase_c PF02518.26 KFX92462.1 - 8e-08 32.8 0.1 2.3e-07 31.3 0.1 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Inhibitor_I66 PF16850.5 KFX92462.1 - 0.15 11.9 0.0 0.38 10.6 0.0 1.6 1 0 0 1 1 1 0 Peptidase inhibitor I66 tRNA-synt_1 PF00133.22 KFX92463.1 - 1.5e-220 733.5 1.6 1.6e-219 730.1 1.6 2.0 1 1 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 KFX92463.1 - 5.3e-31 107.6 0.7 1.2e-30 106.5 0.7 1.6 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 KFX92463.1 - 9.6e-16 57.5 0.2 8.1e-08 31.4 0.0 4.2 4 1 0 4 4 4 3 tRNA synthetases class I (M) tRNA-synt_1_2 PF13603.6 KFX92463.1 - 1.8e-13 50.4 0.1 2e-09 37.3 0.0 3.1 1 1 1 2 2 2 2 Leucyl-tRNA synthetase, Domain 2 Val_tRNA-synt_C PF10458.9 KFX92463.1 - 0.00073 19.8 5.4 0.00073 19.8 5.4 2.9 2 1 0 2 2 2 1 Valyl tRNA synthetase tRNA binding arm tRNA-synt_1e PF01406.19 KFX92463.1 - 0.0029 17.0 0.0 0.029 13.7 0.0 2.4 2 0 0 2 2 2 1 tRNA synthetases class I (C) catalytic domain Fusion_gly PF00523.18 KFX92463.1 - 0.022 13.0 0.1 0.035 12.4 0.1 1.2 1 0 0 1 1 1 0 Fusion glycoprotein F0 PepSY PF03413.19 KFX92463.1 - 0.058 14.0 0.0 0.42 11.2 0.0 2.5 1 0 0 1 1 1 0 Peptidase propeptide and YPEB domain CCDC53 PF10152.9 KFX92463.1 - 2.8 8.4 7.5 7.1 7.0 7.5 1.7 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex Pentaxin PF00354.17 KFX92464.1 - 0.0038 16.9 0.2 0.0044 16.7 0.2 1.0 1 0 0 1 1 1 1 Pentaxin family Sel1 PF08238.12 KFX92465.1 - 3e-37 126.2 35.0 6.1e-06 26.7 0.6 8.2 8 0 0 8 8 8 7 Sel1 repeat TPR_6 PF13174.6 KFX92465.1 - 0.5 11.1 10.2 1.8 9.3 0.0 4.9 5 0 0 5 5 5 0 Tetratricopeptide repeat zf-C3HC4_2 PF13923.6 KFX92466.1 - 5.3e-08 32.6 8.3 2.4e-07 30.5 2.9 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KFX92466.1 - 1.6e-07 31.5 9.1 6.9e-07 29.5 4.4 2.4 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4 PF00097.25 KFX92466.1 - 1.9e-05 24.4 2.4 1.9e-05 24.4 2.4 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 KFX92466.1 - 3.1e-05 23.6 8.4 3.2e-05 23.6 5.7 2.2 2 0 0 2 2 2 1 RING-like zinc finger zf-RING_UBOX PF13445.6 KFX92466.1 - 0.00026 21.0 8.9 0.0003 20.7 3.5 2.7 2 1 0 2 2 2 1 RING-type zinc-finger zf-RING-like PF08746.11 KFX92466.1 - 0.0045 17.3 2.5 0.0045 17.3 2.5 2.5 3 0 0 3 3 3 1 RING-like domain Rad50_zn_hook PF04423.14 KFX92466.1 - 0.022 14.6 0.4 0.022 14.6 0.4 1.7 2 0 0 2 2 2 0 Rad50 zinc hook motif zf-C2H2_6 PF13912.6 KFX92466.1 - 0.034 14.2 1.5 7.7 6.6 0.1 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C3HC4_3 PF13920.6 KFX92466.1 - 0.13 12.2 7.7 2.7 7.9 3.0 2.4 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 KFX92466.1 - 0.24 11.7 11.1 0.44 10.9 6.5 2.9 2 1 0 2 2 2 0 RING-H2 zinc finger domain Zn_ribbon_17 PF17120.5 KFX92466.1 - 0.4 10.4 8.3 0.13 11.9 5.2 1.7 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type zf-RING_5 PF14634.6 KFX92466.1 - 1.1 9.3 6.9 12 5.9 3.2 2.4 2 0 0 2 2 2 0 zinc-RING finger domain zf-C3HC4_4 PF15227.6 KFX92466.1 - 5.1 7.3 8.8 0.72 10.1 3.0 2.3 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING Pro-kuma_activ PF09286.11 KFX92468.1 - 1.6e-37 128.9 0.1 1.7e-21 77.0 0.0 2.4 2 0 0 2 2 2 2 Pro-kumamolisin, activation domain MRVI1 PF05781.12 KFX92469.1 - 0.14 10.9 0.1 0.15 10.8 0.1 1.0 1 0 0 1 1 1 0 MRVI1 protein PLDc PF00614.22 KFX92470.1 - 2.1e-17 62.5 0.4 7.6e-08 32.2 0.2 2.9 2 0 0 2 2 2 2 Phospholipase D Active site motif PLDc_2 PF13091.6 KFX92470.1 - 1.7e-12 47.4 0.0 9.1e-07 28.8 0.0 3.0 2 1 0 2 2 2 2 PLD-like domain PX PF00787.24 KFX92470.1 - 9e-07 28.9 0.0 2.6e-06 27.4 0.0 1.8 1 0 0 1 1 1 1 PX domain APH PF01636.23 KFX92471.1 - 0.084 12.8 0.0 0.13 12.2 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family F-box PF00646.33 KFX92472.1 - 8e-06 25.6 0.8 1.2e-05 25.0 0.0 1.7 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.7 KFX92472.1 - 0.00024 20.9 0.2 0.00062 19.6 0.2 1.7 1 0 0 1 1 1 1 F-box-like F-box_4 PF15966.5 KFX92472.1 - 0.073 13.0 0.0 0.17 11.8 0.0 1.6 1 0 0 1 1 1 0 F-box Med27 PF11571.8 KFX92472.1 - 0.41 11.0 3.0 2.7 8.4 1.2 2.5 1 1 1 2 2 2 0 Mediator complex subunit 27 ANAPC4_WD40 PF12894.7 KFX92476.1 - 0.0014 18.9 0.0 0.0061 16.8 0.0 2.0 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KFX92476.1 - 0.0027 18.5 0.2 0.0076 17.1 0.2 1.8 1 0 0 1 1 1 1 WD domain, G-beta repeat BUD22 PF09073.10 KFX92476.1 - 0.003 16.9 27.2 0.005 16.2 27.2 1.3 1 0 0 1 1 1 1 BUD22 PI3K_1B_p101 PF10486.9 KFX92476.1 - 0.013 13.3 14.3 0.018 12.8 14.3 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit TFIIF_alpha PF05793.12 KFX92476.1 - 0.081 11.5 25.6 0.12 10.9 25.6 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) HEAT_PBS PF03130.16 KFX92476.1 - 0.12 13.1 1.0 18 6.4 0.0 3.6 3 0 0 3 3 3 0 PBS lyase HEAT-like repeat Nop14 PF04147.12 KFX92476.1 - 0.16 10.2 24.7 0.25 9.5 24.7 1.2 1 0 0 1 1 1 0 Nop14-like family DUF4763 PF15960.5 KFX92476.1 - 0.42 9.9 10.4 0.88 8.8 10.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4763) F-box-like PF12937.7 KFX92476.1 - 0.49 10.3 3.9 0.53 10.2 0.0 2.8 2 1 0 2 2 2 0 F-box-like CDC45 PF02724.14 KFX92476.1 - 3.8 5.7 18.2 6.2 5.0 18.2 1.2 1 0 0 1 1 1 0 CDC45-like protein ALS2CR11 PF15729.5 KFX92476.1 - 7.3 5.6 12.7 12 4.9 12.7 1.2 1 0 0 1 1 1 0 Amyotrophic lateral sclerosis 2 candidate 11 RNA_pol_3_Rpc31 PF11705.8 KFX92476.1 - 8.6 6.5 28.2 19 5.4 28.2 1.5 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 PTPRCAP PF15713.5 KFX92476.1 - 8.7 6.6 24.8 21 5.4 24.8 1.6 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated Lin-8 PF03353.15 KFX92476.1 - 9.3 5.7 15.6 16 4.9 15.6 1.3 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Glyco_hydro_18 PF00704.28 KFX92477.1 - 1.4e-73 248.3 1.1 2.6e-73 247.5 1.1 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Chitin_bind_1 PF00187.19 KFX92477.1 - 4.1e-13 49.6 12.2 4.1e-13 49.6 12.2 4.8 5 0 0 5 5 5 2 Chitin recognition protein LysM PF01476.20 KFX92478.1 - 8.8e-16 57.7 8.6 2.5e-05 24.2 0.0 7.0 8 0 0 8 8 8 5 LysM domain DLH PF01738.18 KFX92481.1 - 6e-08 32.5 0.7 7.1e-07 29.0 0.7 1.9 1 1 0 1 1 1 1 Dienelactone hydrolase family Peptidase_S15 PF02129.18 KFX92481.1 - 7.7e-06 25.7 0.0 9.5e-06 25.4 0.0 1.0 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) BAAT_C PF08840.11 KFX92481.1 - 1.1e-05 25.5 0.0 1.4e-05 25.1 0.0 1.2 1 0 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal Peptidase_S9 PF00326.21 KFX92481.1 - 1.5e-05 24.6 0.4 0.00012 21.7 0.1 2.0 1 1 1 2 2 2 1 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 KFX92481.1 - 0.0014 17.9 0.1 0.0019 17.5 0.1 1.3 1 1 0 1 1 1 1 Serine aminopeptidase, S33 AXE1 PF05448.12 KFX92481.1 - 0.002 16.8 0.0 0.0035 16.1 0.0 1.3 1 0 0 1 1 1 1 Acetyl xylan esterase (AXE1) Abhydrolase_1 PF00561.20 KFX92481.1 - 0.018 14.7 0.1 0.021 14.5 0.1 1.1 1 0 0 1 1 1 0 alpha/beta hydrolase fold PAF-AH_p_II PF03403.13 KFX92481.1 - 0.057 11.9 0.2 5.8 5.3 0.0 2.0 1 1 1 2 2 2 0 Platelet-activating factor acetylhydrolase, isoform II Esterase PF00756.20 KFX92481.1 - 0.091 12.4 0.0 0.16 11.6 0.0 1.6 1 1 0 1 1 1 0 Putative esterase DUF1100 PF06500.11 KFX92481.1 - 0.19 10.5 0.0 0.19 10.5 0.0 1.0 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1100) Methyltransf_25 PF13649.6 KFX92483.1 - 5.2e-12 46.3 0.1 1.2e-11 45.1 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 KFX92483.1 - 1.5e-11 44.7 0.0 3.4e-11 43.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KFX92483.1 - 2.4e-11 43.7 0.2 3.9e-11 43.1 0.2 1.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KFX92483.1 - 1.1e-09 39.0 0.0 1.6e-09 38.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KFX92483.1 - 2.3e-09 37.2 0.0 3.2e-09 36.8 0.0 1.3 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KFX92483.1 - 2.3e-07 30.4 0.0 1.5e-06 27.8 0.0 2.0 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family TPMT PF05724.11 KFX92483.1 - 0.02 14.6 0.0 0.24 11.0 0.0 2.1 2 0 0 2 2 2 0 Thiopurine S-methyltransferase (TPMT) MTS PF05175.14 KFX92483.1 - 0.066 12.8 0.0 0.14 11.7 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase small domain His_Phos_1 PF00300.22 KFX92484.1 - 3.8e-33 114.8 0.2 1.1e-17 64.3 0.0 2.3 2 1 0 2 2 2 2 Histidine phosphatase superfamily (branch 1) Tim17 PF02466.19 KFX92488.1 - 1.7e-32 112.1 8.5 2.1e-32 111.8 8.5 1.1 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family HATPase_c_4 PF13749.6 KFX92488.1 - 0.12 12.5 0.0 0.28 11.4 0.0 1.6 1 1 0 1 1 1 0 Putative ATP-dependent DNA helicase recG C-terminal DUF116 PF01976.17 KFX92488.1 - 0.25 10.8 0.1 0.31 10.5 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function DUF116 DUF2235 PF09994.9 KFX92510.1 - 2.7e-28 99.2 0.0 3.9e-28 98.6 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) Fungal_trans PF04082.18 KFX92511.1 - 5.8e-20 71.4 0.0 9.3e-20 70.8 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.26 KFX92511.1 - 8.9e-08 32.2 14.3 0.0008 19.7 2.7 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KFX92511.1 - 8.2e-06 26.0 6.9 8.2e-06 26.0 6.9 2.6 2 0 0 2 2 2 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 KFX92511.1 - 0.0014 19.3 13.3 0.17 12.8 2.7 2.9 2 0 0 2 2 2 2 C2H2-type zinc finger Pex14_N PF04695.13 KFX92524.1 - 1.3e-37 129.9 1.7 1.3e-37 129.9 1.7 3.1 2 2 0 2 2 1 1 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF3584 PF12128.8 KFX92524.1 - 0.00055 17.6 6.9 0.00076 17.2 6.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) Lebercilin PF15619.6 KFX92524.1 - 0.0059 16.3 3.9 0.01 15.5 3.9 1.3 1 0 0 1 1 1 1 Ciliary protein causing Leber congenital amaurosis disease DUF1043 PF06295.12 KFX92524.1 - 0.0069 16.4 0.5 0.015 15.3 0.5 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1043) CENP-Q PF13094.6 KFX92524.1 - 0.037 14.2 5.5 0.068 13.4 5.5 1.4 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit WD40_alt PF14077.6 KFX92524.1 - 0.038 13.9 0.7 0.11 12.3 0.2 1.9 1 1 1 2 2 2 0 Alternative WD40 repeat motif CALCOCO1 PF07888.11 KFX92524.1 - 0.059 12.2 9.2 0.13 11.1 8.5 1.7 1 1 1 2 2 2 0 Calcium binding and coiled-coil domain (CALCOCO1) like SKA1 PF07160.12 KFX92524.1 - 0.069 13.0 0.5 0.13 12.1 0.4 1.4 1 1 0 1 1 1 0 Spindle and kinetochore-associated protein 1 DCB PF16213.5 KFX92524.1 - 0.071 12.8 0.9 0.1 12.3 0.9 1.1 1 0 0 1 1 1 0 Dimerisation and cyclophilin-binding domain of Mon2 Spc7 PF08317.11 KFX92524.1 - 0.14 11.0 3.1 0.25 10.2 3.1 1.4 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF4407 PF14362.6 KFX92524.1 - 0.61 9.4 5.3 1.6 8.0 2.9 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) PRKG1_interact PF15898.5 KFX92524.1 - 0.9 10.5 6.0 1.4 9.9 5.4 1.6 1 1 0 1 1 1 0 cGMP-dependent protein kinase interacting domain zf-C4H2 PF10146.9 KFX92524.1 - 0.95 9.7 5.7 0.11 12.7 0.4 2.0 2 0 0 2 2 2 0 Zinc finger-containing protein AAA PF00004.29 KFX92526.1 - 1e-52 178.1 0.0 2.1e-38 131.7 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KFX92526.1 - 2.7e-10 40.6 0.1 0.0006 20.1 0.0 3.9 2 2 1 3 3 3 2 AAA domain AAA_lid_3 PF17862.1 KFX92526.1 - 4.6e-10 39.1 0.5 1.5e-09 37.5 0.0 2.1 2 0 0 2 2 2 1 AAA+ lid domain AAA_16 PF13191.6 KFX92526.1 - 5.3e-10 40.0 0.0 0.0016 18.8 0.0 3.0 2 0 0 2 2 2 2 AAA ATPase domain CDC48_2 PF02933.17 KFX92526.1 - 1.2e-09 37.8 0.3 5.6e-08 32.4 0.0 2.6 2 0 0 2 2 2 1 Cell division protein 48 (CDC48), domain 2 RuvB_N PF05496.12 KFX92526.1 - 1.3e-07 31.5 0.1 0.0096 15.7 0.0 3.0 2 1 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain RNA_helicase PF00910.22 KFX92526.1 - 3e-07 30.8 0.0 0.031 14.6 0.0 2.7 2 0 0 2 2 2 2 RNA helicase TIP49 PF06068.13 KFX92526.1 - 3.4e-07 29.8 0.0 0.011 14.9 0.0 2.3 2 0 0 2 2 2 2 TIP49 P-loop domain AAA_5 PF07728.14 KFX92526.1 - 5.2e-07 29.7 0.0 0.0024 17.9 0.0 2.8 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 KFX92526.1 - 7.7e-07 29.4 0.2 0.00055 20.1 0.1 2.9 2 2 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_24 PF13479.6 KFX92526.1 - 1.5e-06 28.1 0.0 0.0091 15.7 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_14 PF13173.6 KFX92526.1 - 2.1e-06 27.8 0.0 0.022 14.8 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.6 KFX92526.1 - 5.7e-06 26.9 0.0 0.024 15.2 0.0 3.2 3 0 0 3 3 3 1 AAA domain Sigma54_activat PF00158.26 KFX92526.1 - 1e-05 25.3 0.0 0.083 12.6 0.0 2.5 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_33 PF13671.6 KFX92526.1 - 1.3e-05 25.3 0.0 0.094 12.9 0.0 2.5 2 0 0 2 2 2 2 AAA domain TsaE PF02367.17 KFX92526.1 - 1.5e-05 25.0 0.0 0.18 11.8 0.0 2.4 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE IstB_IS21 PF01695.17 KFX92526.1 - 1.6e-05 24.7 0.2 0.1 12.3 0.0 2.8 3 0 0 3 3 3 2 IstB-like ATP binding protein Mg_chelatase PF01078.21 KFX92526.1 - 1.7e-05 24.3 0.1 0.015 14.6 0.0 2.3 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_7 PF12775.7 KFX92526.1 - 2.8e-05 23.7 0.2 0.033 13.7 0.0 2.7 3 0 0 3 3 2 2 P-loop containing dynein motor region NACHT PF05729.12 KFX92526.1 - 3.4e-05 23.8 0.3 0.039 13.9 0.0 3.2 3 0 0 3 3 3 1 NACHT domain NB-ARC PF00931.22 KFX92526.1 - 8.4e-05 21.9 0.0 0.41 9.8 0.0 2.5 2 0 0 2 2 2 2 NB-ARC domain ABC_tran PF00005.27 KFX92526.1 - 8.8e-05 23.0 0.1 0.34 11.4 0.1 2.6 2 0 0 2 2 2 2 ABC transporter ATPase_2 PF01637.18 KFX92526.1 - 0.00015 21.7 0.4 7.5 6.4 0.0 4.1 2 2 2 4 4 4 0 ATPase domain predominantly from Archaea CDC48_N PF02359.18 KFX92526.1 - 0.00037 20.6 0.0 0.001 19.2 0.0 1.7 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), N-terminal domain ATPase PF06745.13 KFX92526.1 - 0.00067 19.1 0.4 0.029 13.7 0.3 2.3 2 0 0 2 2 2 1 KaiC TniB PF05621.11 KFX92526.1 - 0.0011 18.4 0.3 3.4 7.0 0.1 3.9 3 1 0 3 3 3 1 Bacterial TniB protein AAA_30 PF13604.6 KFX92526.1 - 0.0017 18.1 0.0 0.84 9.3 0.0 2.5 2 0 0 2 2 2 1 AAA domain PhoH PF02562.16 KFX92526.1 - 0.0017 17.8 0.0 2.2 7.7 0.0 2.4 2 0 0 2 2 2 2 PhoH-like protein AAA_28 PF13521.6 KFX92526.1 - 0.0026 18.0 0.0 0.92 9.7 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.6 KFX92526.1 - 0.0029 17.2 0.8 2.1 7.9 0.0 2.8 3 0 0 3 3 2 1 AAA domain ResIII PF04851.15 KFX92526.1 - 0.0034 17.4 0.0 1.1 9.2 0.0 2.7 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DUF2075 PF09848.9 KFX92526.1 - 0.0073 15.6 0.2 2 7.6 0.1 2.7 2 1 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) Zeta_toxin PF06414.12 KFX92526.1 - 0.014 14.7 0.0 0.93 8.7 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin AAA_11 PF13086.6 KFX92526.1 - 0.014 15.1 0.0 1 9.1 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.6 KFX92526.1 - 0.017 15.6 0.0 4.6 7.7 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.6 KFX92526.1 - 0.021 15.1 0.0 1 9.7 0.0 3.2 4 0 0 4 4 3 0 AAA domain Parvo_NS1 PF01057.17 KFX92526.1 - 0.022 13.9 0.0 0.35 9.9 0.0 2.1 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 AAA_3 PF07726.11 KFX92526.1 - 0.036 13.9 0.0 1.6 8.6 0.0 2.4 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) SRP54 PF00448.22 KFX92526.1 - 0.043 13.4 0.1 2 8.0 0.0 2.5 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_29 PF13555.6 KFX92526.1 - 0.05 13.4 0.1 5.4 6.8 0.0 2.7 2 0 0 2 2 2 0 P-loop containing region of AAA domain DUF815 PF05673.13 KFX92526.1 - 0.087 12.0 0.0 5.9 6.0 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF815) Cytidylate_kin PF02224.18 KFX92526.1 - 0.089 12.5 0.0 4 7.1 0.0 2.4 2 0 0 2 2 2 0 Cytidylate kinase CPT PF07931.12 KFX92526.1 - 0.11 12.3 0.1 2.4 8.0 0.0 2.3 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein Rad17 PF03215.15 KFX92526.1 - 0.12 12.3 0.0 13 5.6 0.0 2.6 2 0 0 2 2 2 0 Rad17 P-loop domain Vps4_C PF09336.10 KFX92526.1 - 0.12 12.4 0.1 0.44 10.6 0.0 2.0 2 0 0 2 2 1 0 Vps4 C terminal oligomerisation domain RasGEF PF00617.19 KFX92527.1 - 2.6e-39 135.2 0.3 4.1e-39 134.6 0.3 1.3 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 KFX92527.1 - 3.1e-07 30.6 0.2 1.4e-06 28.5 0.2 2.2 1 1 0 1 1 1 1 RasGEF N-terminal motif BDHCT PF08072.11 KFX92528.1 - 0.00038 20.5 1.0 0.36 10.9 0.0 3.1 3 0 0 3 3 3 2 BDHCT (NUC031) domain Methyltransf_25 PF13649.6 KFX92529.1 - 7.8e-20 71.4 0.3 5.9e-18 65.4 0.0 3.1 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_31 PF13847.6 KFX92529.1 - 2.5e-16 59.9 0.0 1.3e-15 57.5 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 KFX92529.1 - 7.9e-13 48.9 0.2 9.3e-12 45.4 0.0 2.6 3 0 0 3 3 3 1 Methyltransferase domain SET PF00856.28 KFX92529.1 - 2.3e-12 47.6 0.0 4.4e-12 46.7 0.0 1.5 1 0 0 1 1 1 1 SET domain Ubie_methyltran PF01209.18 KFX92529.1 - 3.2e-11 43.0 0.0 6.6e-11 42.0 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 KFX92529.1 - 3.1e-06 27.8 0.0 1.1e-05 26.0 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.14 KFX92529.1 - 3.3e-06 26.8 0.0 6.7e-06 25.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_4 PF02390.17 KFX92529.1 - 1.4e-05 24.6 0.0 0.00012 21.6 0.0 2.1 2 0 0 2 2 2 1 Putative methyltransferase Methyltransf_23 PF13489.6 KFX92529.1 - 0.00041 20.2 0.0 0.00078 19.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.15 KFX92529.1 - 0.0071 16.2 0.1 0.026 14.4 0.1 1.9 1 1 0 1 1 1 1 Hypothetical methyltransferase TehB PF03848.14 KFX92529.1 - 0.015 14.7 0.0 0.034 13.5 0.0 1.5 1 0 0 1 1 1 0 Tellurite resistance protein TehB Methyltransf_18 PF12847.7 KFX92529.1 - 0.16 11.9 0.0 0.35 10.8 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain RRM_1 PF00076.22 KFX92531.1 - 4.6e-09 36.0 2.9 1e-08 34.8 0.0 2.7 3 0 0 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TT_ORF2 PF02957.15 KFX92531.1 - 0.029 15.3 4.8 0.029 15.3 4.8 3.4 3 0 0 3 3 3 0 TT viral ORF2 FAM91_C PF14648.6 KFX92531.1 - 0.12 11.2 0.3 0.17 10.7 0.3 1.2 1 0 0 1 1 1 0 FAM91 C-terminus TFIIF_alpha PF05793.12 KFX92531.1 - 0.23 10.0 32.0 0.51 8.9 32.0 1.6 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Sds3 PF08598.11 KFX92532.1 - 5.2e-16 59.3 2.3 5.2e-16 59.3 2.3 2.7 2 1 0 2 2 2 1 Sds3-like Coiled-coil_56 PF09813.9 KFX92533.1 - 9e-05 22.5 0.0 9.8e-05 22.3 0.0 1.1 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 56 DUF3453 PF11935.8 KFX92534.1 - 2.3e-71 240.0 0.0 7.3e-71 238.4 0.0 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF3453) Svf1_C PF17187.4 KFX92534.1 - 0.035 13.9 0.0 0.07 13.0 0.0 1.4 1 0 0 1 1 1 0 Svf1-like C-terminal lipocalin-like domain XPC-binding PF09280.11 KFX92534.1 - 0.079 12.7 0.1 2.3 8.0 0.0 2.9 3 0 0 3 3 3 0 XPC-binding domain SASP PF00269.20 KFX92535.1 - 0.02 14.9 0.3 15 5.7 0.0 3.6 3 0 0 3 3 3 0 Small, acid-soluble spore proteins, alpha/beta type Chorion_2 PF03964.15 KFX92535.1 - 0.15 12.9 1.2 0.26 12.2 0.3 1.9 2 0 0 2 2 2 0 Chorion family 2 Fib_alpha PF08702.10 KFX92535.1 - 2.7 8.2 11.9 6.9 6.8 5.9 2.5 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family DUF3584 PF12128.8 KFX92535.1 - 3.8 4.9 30.7 0.14 9.6 16.7 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) DUF4407 PF14362.6 KFX92535.1 - 8.2 5.7 25.5 5.5 6.3 22.8 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) Spy1 PF11357.8 KFX92541.1 - 0.14 12.5 0.4 0.21 11.9 0.4 1.2 1 0 0 1 1 1 0 Cell cycle regulatory protein DUF4734 PF15881.5 KFX92542.1 - 0.11 12.7 0.0 0.16 12.2 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4734) UPF0444 PF15475.6 KFX92543.1 - 0.0072 16.6 2.1 0.019 15.2 2.1 1.7 1 1 0 1 1 1 1 Transmembrane protein C12orf23, UPF0444 Asp PF00026.23 KFX92552.1 - 1.1e-62 212.2 1.9 1.4e-62 211.9 1.9 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KFX92552.1 - 3.5e-09 37.2 1.8 6.1e-07 29.8 1.8 2.7 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 KFX92552.1 - 0.001 19.7 0.7 1.2 9.8 0.1 3.7 2 1 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.6 KFX92552.1 - 0.021 15.3 0.1 4.1 8.0 0.0 3.7 2 1 1 3 3 3 0 gag-polyprotein putative aspartyl protease TAXi_C PF14541.6 KFX92552.1 - 0.13 12.1 0.0 0.35 10.6 0.0 1.8 1 1 0 1 1 1 0 Xylanase inhibitor C-terminal Cytomega_UL20A PF05984.12 KFX92554.1 - 0.15 12.4 0.1 0.2 12.0 0.1 1.3 1 1 0 1 1 1 0 Cytomegalovirus UL20A protein Aldedh PF00171.22 KFX92555.1 - 0.16 10.4 1.4 0.18 10.3 1.4 1.0 1 0 0 1 1 1 0 Aldehyde dehydrogenase family SesA PF17107.5 KFX92558.1 - 2.2e-24 86.0 0.1 6.4e-24 84.5 0.2 1.8 2 0 0 2 2 2 1 N-terminal domain on NACHT_NTPase and P-loop NTPases NB-ARC PF00931.22 KFX92558.1 - 1e-09 38.0 0.0 1.6e-09 37.4 0.0 1.2 1 0 0 1 1 1 1 NB-ARC domain AAA_16 PF13191.6 KFX92558.1 - 0.00059 20.3 0.0 0.0014 19.0 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain ATPase_2 PF01637.18 KFX92558.1 - 0.0019 18.1 0.0 0.0036 17.3 0.0 1.4 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea AAA_22 PF13401.6 KFX92558.1 - 0.022 15.0 0.0 0.075 13.3 0.0 1.9 2 0 0 2 2 2 0 AAA domain DAP3 PF10236.9 KFX92558.1 - 0.04 13.1 0.0 0.064 12.4 0.0 1.3 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 GP57 PF17594.2 KFX92558.1 - 0.084 12.6 0.0 9 6.1 0.0 2.6 2 0 0 2 2 2 0 Phage Tail fiber assembly helper gene product 57 HEAT_2 PF13646.6 KFX92558.1 - 0.82 10.1 3.1 25 5.3 0.1 3.2 4 0 0 4 4 4 0 HEAT repeats TPP_enzyme_N PF02776.18 KFX92559.1 - 6.3e-36 123.6 0.0 2.4e-35 121.6 0.0 1.8 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.21 KFX92559.1 - 1.2e-16 60.8 0.0 3e-16 59.6 0.0 1.7 1 1 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.22 KFX92559.1 - 9e-07 28.7 0.0 4.8e-06 26.3 0.0 2.2 3 0 0 3 3 3 1 Thiamine pyrophosphate enzyme, central domain Gly_transf_sug PF04488.15 KFX92560.1 - 4.3e-07 30.5 0.0 1e-06 29.3 0.0 1.6 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif ABC_membrane PF00664.23 KFX92561.1 - 9.8e-92 307.5 22.6 4.5e-49 167.5 8.6 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 KFX92561.1 - 5.6e-59 198.6 0.0 2e-28 99.6 0.0 2.5 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 KFX92561.1 - 3.3e-18 65.9 0.1 8.3e-09 35.2 0.0 4.1 3 1 1 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 KFX92561.1 - 1.9e-08 34.7 2.1 0.013 15.8 0.1 4.1 2 2 0 2 2 2 2 AAA domain AAA_21 PF13304.6 KFX92561.1 - 2e-07 31.1 0.0 0.12 12.2 0.0 4.5 4 0 0 4 4 4 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 KFX92561.1 - 9.4e-07 29.4 0.1 0.035 14.5 0.0 3.3 3 0 0 3 3 2 2 AAA ATPase domain AAA_29 PF13555.6 KFX92561.1 - 9.7e-07 28.4 2.1 0.028 14.2 0.3 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_25 PF13481.6 KFX92561.1 - 2.2e-06 27.4 0.1 0.088 12.4 0.1 2.9 2 0 0 2 2 2 2 AAA domain RsgA_GTPase PF03193.16 KFX92561.1 - 2.2e-06 27.7 0.1 0.041 13.8 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase ABC_ATPase PF09818.9 KFX92561.1 - 2.5e-05 23.3 0.3 0.36 9.6 0.1 3.1 3 0 0 3 3 3 2 Predicted ATPase of the ABC class AAA_5 PF07728.14 KFX92561.1 - 0.0002 21.4 0.7 1.7 8.7 0.1 3.5 3 0 0 3 3 3 2 AAA domain (dynein-related subfamily) AAA_18 PF13238.6 KFX92561.1 - 0.00044 20.8 0.3 1.1 9.8 0.0 2.9 2 1 0 2 2 2 1 AAA domain AAA_33 PF13671.6 KFX92561.1 - 0.001 19.3 0.0 0.27 11.4 0.0 2.7 2 0 0 2 2 2 1 AAA domain SbcCD_C PF13558.6 KFX92561.1 - 0.0021 18.2 0.2 2.8 8.2 0.0 3.6 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_23 PF13476.6 KFX92561.1 - 0.0036 17.8 4.2 0.081 13.4 0.4 2.4 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 KFX92561.1 - 0.0037 17.0 1.2 3.9 7.1 0.2 3.2 3 0 0 3 3 3 1 AAA domain AAA_7 PF12775.7 KFX92561.1 - 0.005 16.4 0.1 2.1 7.8 0.1 2.4 2 0 0 2 2 2 1 P-loop containing dynein motor region RNA_helicase PF00910.22 KFX92561.1 - 0.0084 16.5 0.3 4.3 7.8 0.0 3.0 3 0 0 3 3 2 1 RNA helicase MMR_HSR1 PF01926.23 KFX92561.1 - 0.012 15.7 1.1 4.3 7.5 0.0 3.2 3 0 0 3 3 2 0 50S ribosome-binding GTPase IstB_IS21 PF01695.17 KFX92561.1 - 0.017 14.9 0.7 3 7.6 0.0 3.4 3 0 0 3 3 3 0 IstB-like ATP binding protein DUF2178 PF09946.9 KFX92561.1 - 0.027 14.7 1.3 0.19 11.9 0.0 2.7 2 0 0 2 2 2 0 Predicted membrane protein (DUF2178) PhoH PF02562.16 KFX92561.1 - 0.03 13.8 3.2 3.5 7.0 0.1 3.4 3 0 0 3 3 3 0 PhoH-like protein T2SSE PF00437.20 KFX92561.1 - 0.035 13.2 0.5 4.3 6.3 0.1 2.3 2 0 0 2 2 2 0 Type II/IV secretion system protein DUF3987 PF13148.6 KFX92561.1 - 0.035 13.1 0.1 7.4 5.5 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3987) APS_kinase PF01583.20 KFX92561.1 - 0.036 14.0 0.8 2.1 8.2 0.0 2.7 2 0 0 2 2 2 0 Adenylylsulphate kinase AAA_24 PF13479.6 KFX92561.1 - 0.046 13.4 3.9 0.58 9.8 0.3 2.6 2 1 0 2 2 2 0 AAA domain FtsK_SpoIIIE PF01580.18 KFX92561.1 - 0.064 12.6 0.4 12 5.2 0.3 3.3 3 0 0 3 3 3 0 FtsK/SpoIIIE family AAA_15 PF13175.6 KFX92561.1 - 0.068 12.9 0.1 12 5.5 0.0 2.5 2 0 0 2 2 2 0 AAA ATPase domain Mg_chelatase PF01078.21 KFX92561.1 - 0.082 12.3 0.1 0.88 8.9 0.1 2.3 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA PF00004.29 KFX92561.1 - 0.12 12.8 0.2 2.2 8.7 0.0 2.9 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) NACHT PF05729.12 KFX92561.1 - 0.12 12.3 0.2 3.2 7.7 0.1 2.6 2 0 0 2 2 2 0 NACHT domain Zeta_toxin PF06414.12 KFX92561.1 - 0.17 11.1 0.2 8 5.7 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin ATP-synt_ab PF00006.25 KFX92561.1 - 0.17 11.5 0.2 9.2 5.8 0.0 2.7 3 0 0 3 3 3 0 ATP synthase alpha/beta family, nucleotide-binding domain NB-ARC PF00931.22 KFX92561.1 - 0.3 10.2 1.3 5.1 6.2 0.2 2.3 2 0 0 2 2 2 0 NB-ARC domain DUF87 PF01935.17 KFX92561.1 - 0.43 10.6 6.5 7.9 6.5 0.3 2.5 2 0 0 2 2 2 0 Helicase HerA, central domain Polysacc_synt_4 PF04669.13 KFX92562.1 - 3.9e-22 78.7 1.1 1.1e-20 74.0 1.1 2.0 1 1 0 1 1 1 1 Polysaccharide biosynthesis DUF2491 PF10679.9 KFX92562.1 - 0.0057 15.9 1.0 0.0066 15.7 1.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2491) ketoacyl-synt PF00109.26 KFX92568.1 - 3.8e-56 190.5 3.4 2.5e-54 184.6 1.7 2.4 2 1 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 KFX92568.1 - 5.2e-07 29.7 0.1 1.8e-06 28.0 0.0 1.9 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain Thiolase_N PF00108.23 KFX92568.1 - 0.00023 20.6 0.5 0.00051 19.5 0.1 1.7 2 0 0 2 2 2 1 Thiolase, N-terminal domain PPR_2 PF13041.6 KFX92579.1 - 1.7e-48 162.6 3.5 3.4e-09 36.8 0.0 13.1 10 3 4 14 14 14 9 PPR repeat family PPR_3 PF13812.6 KFX92579.1 - 2.1e-34 117.4 0.0 0.0033 17.5 0.0 10.9 9 2 2 11 11 11 8 Pentatricopeptide repeat domain PPR PF01535.20 KFX92579.1 - 3.1e-25 86.6 17.4 0.00059 19.9 0.0 13.5 15 0 0 15 15 15 5 PPR repeat PPR_1 PF12854.7 KFX92579.1 - 3.6e-23 81.0 0.6 1.1e-06 28.2 0.0 8.9 10 0 0 10 10 10 4 PPR repeat PPR_long PF17177.4 KFX92579.1 - 2.6e-19 69.4 10.2 2.1e-08 33.8 0.0 5.2 4 1 0 5 5 5 4 Pentacotripeptide-repeat region of PRORP RPM2 PF08579.11 KFX92579.1 - 4e-05 24.0 0.1 0.0046 17.4 0.0 3.5 4 0 0 4 4 4 1 Mitochondrial ribonuclease P subunit (RPM2) TPR_19 PF14559.6 KFX92579.1 - 0.0044 17.5 1.8 4.2 8.0 0.0 5.1 5 0 0 5 5 5 1 Tetratricopeptide repeat OSK PF17182.4 KFX92579.1 - 0.039 13.2 0.0 0.075 12.3 0.0 1.4 1 0 0 1 1 1 0 OSK domain TPR_14 PF13428.6 KFX92579.1 - 0.059 14.2 6.9 4.7 8.3 0.2 6.6 8 1 1 9 9 9 0 Tetratricopeptide repeat Med9 PF07544.13 KFX92582.1 - 3.9e-15 55.7 0.1 6.3e-15 55.0 0.0 1.4 2 0 0 2 2 2 1 RNA polymerase II transcription mediator complex subunit 9 Med21 PF11221.8 KFX92582.1 - 0.0077 16.5 8.0 0.013 15.7 8.0 1.5 1 1 0 1 1 1 1 Subunit 21 of Mediator complex iPGM_N PF06415.13 KFX92583.1 - 2.1e-79 266.0 0.0 3.3e-79 265.3 0.0 1.3 1 0 0 1 1 1 1 BPG-independent PGAM N-terminus (iPGM_N) Metalloenzyme PF01676.18 KFX92583.1 - 3.1e-67 226.5 0.1 3.7e-67 226.3 0.1 1.0 1 0 0 1 1 1 1 Metalloenzyme superfamily Sulfatase PF00884.23 KFX92583.1 - 7.2e-08 32.2 0.0 2.4e-07 30.5 0.0 1.9 1 1 0 1 1 1 1 Sulfatase Phosphodiest PF01663.22 KFX92583.1 - 8.6e-07 28.9 0.0 1.5e-06 28.0 0.0 1.4 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Alk_phosphatase PF00245.20 KFX92583.1 - 0.088 11.7 0.0 0.15 11.0 0.0 1.3 1 0 0 1 1 1 0 Alkaline phosphatase Usp PF00582.26 KFX92586.1 - 2.4e-17 63.8 0.0 6.3e-17 62.4 0.0 1.8 1 0 0 1 1 1 1 Universal stress protein family Paf67 PF10255.9 KFX92587.1 - 4e-157 523.4 0.2 4.8e-157 523.1 0.2 1.0 1 0 0 1 1 1 1 RNA polymerase I-associated factor PAF67 TPR_2 PF07719.17 KFX92587.1 - 0.051 13.7 2.1 0.17 12.1 0.0 3.0 4 0 0 4 4 4 0 Tetratricopeptide repeat RRM_occluded PF16842.5 KFX92588.1 - 0.029 14.2 0.0 0.063 13.2 0.0 1.5 1 0 0 1 1 1 0 Occluded RNA-recognition motif Ku_PK_bind PF08785.11 KFX92589.1 - 1.7e-32 112.1 0.0 3.2e-32 111.2 0.0 1.5 1 0 0 1 1 1 1 Ku C terminal domain like Curto_V2 PF07325.11 KFX92589.1 - 0.0069 16.3 0.1 0.011 15.6 0.1 1.3 1 0 0 1 1 1 1 Curtovirus V2 protein Ku_C PF03730.14 KFX92589.1 - 0.18 12.6 0.9 0.61 10.8 0.2 2.1 1 1 1 2 2 2 0 Ku70/Ku80 C-terminal arm HATPase_c PF02518.26 KFX92606.1 - 3.1e-18 66.3 0.2 2.5e-17 63.4 0.1 2.2 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 KFX92606.1 - 1.8e-05 24.7 0.0 6.8e-05 22.8 0.0 1.9 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain HATPase_c_3 PF13589.6 KFX92606.1 - 0.00019 21.3 0.0 0.00036 20.4 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase GAF_2 PF13185.6 KFX92606.1 - 0.011 16.1 0.0 0.025 14.9 0.0 1.6 1 0 0 1 1 1 0 GAF domain FAD_binding_4 PF01565.23 KFX92607.1 - 0.07 12.9 0.1 0.24 11.1 0.0 2.0 2 0 0 2 2 2 0 FAD binding domain Cu-oxidase_2 PF07731.14 KFX92608.1 - 1.1e-11 44.6 3.0 3.3e-11 43.1 2.0 2.2 2 1 0 2 2 2 1 Multicopper oxidase Cu-oxidase PF00394.22 KFX92608.1 - 0.091 12.9 0.2 0.16 12.1 0.2 1.4 1 0 0 1 1 1 0 Multicopper oxidase TBP PF00352.21 KFX92615.1 - 2.4e-67 222.9 0.1 1.4e-32 111.5 0.1 2.2 2 0 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) DUF3378 PF11858.8 KFX92615.1 - 0.00019 21.5 0.0 0.32 11.2 0.0 2.4 2 0 0 2 2 2 2 Domain of unknown function (DUF3378) ALO PF04030.14 KFX92619.1 - 2.6e-85 286.4 1.5 4.1e-85 285.7 1.5 1.3 1 0 0 1 1 1 1 D-arabinono-1,4-lactone oxidase FAD_binding_4 PF01565.23 KFX92619.1 - 2.1e-27 95.6 0.0 3.7e-27 94.8 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain HC2 PF07382.11 KFX92619.1 - 0.0027 17.8 104.9 0.0071 16.5 64.6 2.2 1 1 1 2 2 2 2 Histone H1-like nucleoprotein HC2 Haem_degrading PF03928.14 KFX92620.1 - 2e-28 98.9 0.0 3e-28 98.2 0.0 1.3 1 1 0 1 1 1 1 Haem-degrading HEAT PF02985.22 KFX92621.1 - 2.1e-13 49.3 16.0 0.00055 20.0 0.2 9.1 11 0 0 11 11 8 3 HEAT repeat HEAT_EZ PF13513.6 KFX92621.1 - 1.1e-09 38.5 0.8 8.7e-07 29.3 0.0 6.9 6 2 2 8 8 8 2 HEAT-like repeat HEAT_2 PF13646.6 KFX92621.1 - 1.2e-07 32.0 13.3 0.0014 18.9 0.2 6.9 3 2 5 8 8 8 4 HEAT repeats DRIM PF07539.12 KFX92621.1 - 5.6e-07 28.3 4.8 0.36 9.1 0.0 5.8 4 3 1 6 6 6 3 Down-regulated in metastasis CLASP_N PF12348.8 KFX92621.1 - 7.8e-07 28.9 1.5 0.11 12.1 0.0 5.6 5 1 1 7 7 7 1 CLASP N terminal IBN_N PF03810.19 KFX92621.1 - 1.8e-06 27.8 1.7 0.00067 19.5 0.3 4.0 3 0 0 3 3 3 1 Importin-beta N-terminal domain Arm PF00514.23 KFX92621.1 - 0.0001 22.2 5.3 0.19 11.8 0.0 5.0 5 0 0 5 5 5 1 Armadillo/beta-catenin-like repeat HEAT_PBS PF03130.16 KFX92621.1 - 0.0058 17.2 1.0 20 6.2 0.0 4.7 4 0 0 4 4 3 0 PBS lyase HEAT-like repeat MMS19_N PF14500.6 KFX92621.1 - 0.0072 15.9 0.5 6.5 6.2 0.0 3.3 3 0 0 3 3 3 2 Dos2-interacting transcription regulator of RNA-Pol-II DUF3385 PF11865.8 KFX92621.1 - 0.018 15.0 3.2 12 5.8 0.0 4.5 3 2 1 4 4 4 0 Domain of unknown function (DUF3385) Cse1 PF08506.10 KFX92621.1 - 0.084 11.7 0.0 4.3 6.1 0.0 3.6 4 1 1 5 5 5 0 Cse1 Sec7_N PF12783.7 KFX92621.1 - 0.14 12.1 0.2 32 4.4 0.0 3.1 3 1 0 3 3 3 0 Guanine nucleotide exchange factor in Golgi transport N-terminal HMGL-like PF00682.19 KFX92622.1 - 1.9e-79 267.0 0.0 2.6e-79 266.5 0.0 1.2 1 0 0 1 1 1 1 HMGL-like LeuA_dimer PF08502.10 KFX92622.1 - 1.6e-24 86.3 0.0 2.9e-24 85.5 0.0 1.4 1 0 0 1 1 1 1 LeuA allosteric (dimerisation) domain Zn_clus PF00172.18 KFX92623.1 - 0.0086 16.2 9.0 0.017 15.2 9.0 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain LSM PF01423.22 KFX92624.1 - 9.5e-10 38.0 0.0 1.3e-09 37.6 0.0 1.2 1 0 0 1 1 1 1 LSM domain FoP_duplication PF13865.6 KFX92624.1 - 0.00048 20.6 12.9 0.00075 20.0 12.9 1.3 1 0 0 1 1 1 1 C-terminal duplication domain of Friend of PRMT1 TYW3 PF02676.14 KFX92625.1 - 3e-74 249.0 0.0 3.7e-74 248.7 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase TYW3 ARPC4 PF05856.12 KFX92627.1 - 7.6e-63 211.1 1.0 8.8e-63 210.9 1.0 1.0 1 0 0 1 1 1 1 ARP2/3 complex 20 kDa subunit (ARPC4) UCH PF00443.29 KFX92628.1 - 1.2e-49 169.1 0.0 1.5e-49 168.8 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KFX92628.1 - 1.4e-12 47.8 2.5 2.6e-07 30.5 0.9 2.4 2 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase ubiquitin PF00240.23 KFX92628.1 - 4e-11 42.5 0.0 1.3e-10 40.9 0.0 1.9 1 0 0 1 1 1 1 Ubiquitin family Coagulase PF08764.10 KFX92628.1 - 0.032 14.4 1.5 0.055 13.7 1.5 1.3 1 0 0 1 1 1 0 Staphylococcus aureus coagulase Terminase_3C PF17288.2 KFX92628.1 - 0.063 13.7 0.3 0.14 12.6 0.3 1.5 1 0 0 1 1 1 0 Terminase RNAseH like domain Pkinase PF00069.25 KFX92632.1 - 2e-09 37.2 0.0 3e-09 36.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFX92632.1 - 0.00082 18.7 0.0 0.0056 16.0 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase Glyco_hydro_9 PF00759.19 KFX92633.1 - 2.2 7.6 8.0 3.5 7.0 8.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 9 DUF2025 PF09634.10 KFX92634.1 - 0.05 13.6 0.0 0.1 12.6 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2025) AOX PF01786.17 KFX92635.1 - 2.4e-93 311.6 0.1 3.1e-93 311.3 0.1 1.1 1 0 0 1 1 1 1 Alternative oxidase Asp4 PF16996.5 KFX92644.1 - 1.6 8.6 5.7 3.1 7.7 3.5 2.6 2 1 0 2 2 2 0 Accessory secretory protein Sec Asp4 PTPLA PF04387.14 KFX92645.1 - 7e-40 136.4 1.9 7e-40 136.4 1.9 1.4 2 0 0 2 2 2 1 Protein tyrosine phosphatase-like protein, PTPLA Pardaxin PF07425.11 KFX92645.1 - 0.074 12.7 1.1 0.37 10.4 0.0 2.5 3 0 0 3 3 3 0 Pardaxin NMO PF03060.15 KFX92664.1 - 4e-36 125.1 0.5 4.8e-36 124.8 0.5 1.0 1 0 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.25 KFX92664.1 - 5.5e-05 22.3 0.4 0.0001 21.4 0.2 1.4 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain TMP-TENI PF02581.17 KFX92664.1 - 0.00038 19.8 0.9 0.0012 18.2 0.3 1.9 2 0 0 2 2 2 1 Thiamine monophosphate synthase NanE PF04131.14 KFX92664.1 - 0.0038 16.5 0.1 0.0089 15.2 0.1 1.7 1 0 0 1 1 1 1 Putative N-acetylmannosamine-6-phosphate epimerase FMN_dh PF01070.18 KFX92664.1 - 0.0085 15.2 1.4 0.013 14.5 1.1 1.5 2 0 0 2 2 2 1 FMN-dependent dehydrogenase Fungal_trans PF04082.18 KFX92665.1 - 9.2e-23 80.6 0.7 1.7e-22 79.7 0.5 1.5 2 0 0 2 2 2 1 Fungal specific transcription factor domain LAMTOR PF15454.6 KFX92682.1 - 1.1e-10 42.0 0.1 1.7e-10 41.3 0.1 1.3 1 0 0 1 1 1 1 Late endosomal/lysosomal adaptor and MAPK and MTOR activator DUF713 PF05218.14 KFX92682.1 - 0.096 12.4 0.0 0.13 12.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF713) Glyco_hydro_45 PF02015.16 KFX92692.1 - 1.7e-21 77.1 0.6 3.2e-21 76.2 0.6 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 45 Pkinase PF00069.25 KFX92692.1 - 7.3e-07 28.8 0.0 1.2e-06 28.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain YrbL-PhoP_reg PF10707.9 KFX92692.1 - 4.6e-05 23.0 0.0 7.6e-05 22.3 0.0 1.2 1 0 0 1 1 1 1 PhoP regulatory network protein YrbL Kdo PF06293.14 KFX92692.1 - 0.0026 17.1 0.0 0.0039 16.6 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family WaaY PF06176.11 KFX92692.1 - 0.0028 17.3 0.0 0.0046 16.6 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide core biosynthesis protein (WaaY) APH PF01636.23 KFX92692.1 - 0.0045 16.9 0.1 0.0068 16.4 0.1 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_Tyr PF07714.17 KFX92692.1 - 0.13 11.6 0.0 0.19 11.0 0.0 1.1 1 0 0 1 1 1 0 Protein tyrosine kinase TrkH PF02386.16 KFX92700.1 - 5.6e-147 490.2 15.2 6.5e-146 486.7 6.6 2.1 2 0 0 2 2 2 2 Cation transport protein ERCC3_RAD25_C PF16203.5 KFX92701.1 - 1.3e-123 411.0 0.1 2.3e-123 410.2 0.1 1.3 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase Helicase_C_3 PF13625.6 KFX92701.1 - 7.6e-35 119.8 0.0 1.9e-34 118.5 0.0 1.7 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KFX92701.1 - 3.9e-16 59.5 0.0 9e-16 58.3 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 KFX92701.1 - 1.7e-13 50.9 0.1 4.3e-13 49.6 0.1 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SNF2_N PF00176.23 KFX92701.1 - 1.1e-08 34.2 0.0 1.4e-08 33.9 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain DEAD PF00270.29 KFX92701.1 - 0.0013 18.5 0.0 0.0024 17.7 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase zf-CHY PF05495.12 KFX92702.1 - 5.4e-13 49.2 17.2 1e-12 48.3 17.2 1.5 1 0 0 1 1 1 1 CHY zinc finger Zn-ribbon_8 PF09723.10 KFX92702.1 - 0.0083 16.2 4.6 0.0083 16.2 4.6 2.7 2 1 1 3 3 3 2 Zinc ribbon domain HypA PF01155.19 KFX92702.1 - 0.024 14.6 1.8 0.024 14.6 1.8 2.1 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Cys_rich_KTR PF14205.6 KFX92702.1 - 0.029 14.2 4.7 1.8 8.4 1.3 2.5 1 1 1 2 2 2 0 Cysteine-rich KTR LIM PF00412.22 KFX92702.1 - 0.23 11.7 13.2 0.2 11.9 9.4 2.3 1 1 1 2 2 2 0 LIM domain TF_Zn_Ribbon PF08271.12 KFX92702.1 - 0.24 10.9 5.9 0.72 9.4 1.3 2.5 2 0 0 2 2 2 0 TFIIB zinc-binding C1_4 PF07975.12 KFX92702.1 - 1.5 9.1 13.7 1e+02 3.3 14.6 2.8 1 1 2 3 3 3 0 TFIIH C1-like domain zinc_ribbon_4 PF13717.6 KFX92702.1 - 3.8 7.5 13.7 0.9 9.5 0.3 3.4 3 0 0 3 3 3 0 zinc-ribbon domain zf-C2H2 PF00096.26 KFX92702.1 - 6.8 7.3 12.6 1.8 9.2 0.9 3.8 4 0 0 4 4 4 0 Zinc finger, C2H2 type Proteasome PF00227.26 KFX92703.1 - 2.3e-55 187.1 0.1 3.1e-55 186.6 0.1 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 KFX92703.1 - 6.1e-13 48.2 0.3 2e-12 46.5 0.1 2.0 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature Terminase_5 PF06056.12 KFX92703.1 - 0.042 13.7 0.1 0.092 12.6 0.1 1.5 1 0 0 1 1 1 0 Putative ATPase subunit of terminase (gpP-like) MAT1-1-2 PF17043.5 KFX92703.1 - 0.15 11.9 0.1 0.24 11.3 0.1 1.3 1 0 0 1 1 1 0 Mating type protein 1-1-2 of unknown function FAD-oxidase_C PF02913.19 KFX92704.1 - 1.3e-64 218.3 0.0 1.8e-64 217.8 0.0 1.2 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 KFX92704.1 - 3.5e-35 120.8 0.5 5.7e-35 120.1 0.5 1.3 1 0 0 1 1 1 1 FAD binding domain Turandot PF07240.11 KFX92704.1 - 0.071 13.1 0.0 0.31 11.0 0.0 2.0 2 0 0 2 2 2 0 Stress-inducible humoral factor Turandot adh_short PF00106.25 KFX92708.1 - 1.7e-45 154.9 0.1 2.6e-45 154.3 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KFX92708.1 - 5e-40 137.5 0.1 7.4e-40 137.0 0.1 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KFX92708.1 - 3.5e-11 43.3 0.0 6e-11 42.6 0.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KFX92708.1 - 1.5e-06 27.8 0.1 3.1e-06 26.8 0.1 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 KFX92708.1 - 4.9e-06 26.6 0.0 8.4e-06 25.8 0.0 1.5 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 KFX92708.1 - 0.00012 21.8 0.1 0.00019 21.1 0.1 1.3 1 0 0 1 1 1 1 NmrA-like family RmlD_sub_bind PF04321.17 KFX92708.1 - 0.00027 20.1 0.1 0.0005 19.3 0.1 1.4 1 0 0 1 1 1 1 RmlD substrate binding domain DUF1776 PF08643.10 KFX92708.1 - 0.0035 16.7 0.0 0.0058 16.0 0.0 1.2 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) F420_oxidored PF03807.17 KFX92708.1 - 0.016 15.8 0.1 0.037 14.6 0.1 1.6 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent DUF2703 PF10865.8 KFX92708.1 - 0.074 13.2 0.0 0.24 11.6 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF2703) GspH PF12019.8 KFX92708.1 - 0.9 10.0 6.0 0.86 10.0 3.1 2.4 2 1 0 2 2 2 0 Type II transport protein GspH MFS_1 PF07690.16 KFX92709.1 - 3.7e-34 118.2 51.6 3.7e-34 118.2 51.6 2.7 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KFX92709.1 - 2.6e-11 43.0 16.6 2.6e-11 43.0 16.6 2.4 2 1 0 2 2 2 1 Sugar (and other) transporter Lip_prot_lig_C PF10437.9 KFX92709.1 - 0.21 11.6 0.0 0.38 10.8 0.0 1.4 1 0 0 1 1 1 0 Bacterial lipoate protein ligase C-terminus Fungal_trans PF04082.18 KFX92710.1 - 1.7e-13 50.2 0.1 3.2e-13 49.3 0.1 1.5 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KFX92710.1 - 5.2e-10 39.3 8.0 1e-09 38.3 8.0 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain adh_short PF00106.25 KFX92711.1 - 4.9e-35 120.7 0.2 6.9e-35 120.3 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KFX92711.1 - 2.3e-22 79.7 0.0 3.8e-22 79.0 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KFX92711.1 - 5.2e-10 39.5 0.0 6.8e-10 39.1 0.0 1.1 1 0 0 1 1 1 1 KR domain FerI PF08151.12 KFX92711.1 - 0.027 14.5 0.0 0.048 13.7 0.0 1.4 1 0 0 1 1 1 0 FerI (NUC094) domain Polysacc_synt_2 PF02719.15 KFX92711.1 - 0.034 13.3 0.1 0.045 12.9 0.1 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein CS PF04969.16 KFX92712.1 - 9.4e-08 33.0 0.2 1.5e-07 32.4 0.2 1.3 1 0 0 1 1 1 1 CS domain Forkhead_N PF08430.12 KFX92712.1 - 0.21 12.2 13.9 0.34 11.5 13.9 1.3 1 0 0 1 1 1 0 Forkhead N-terminal region Aminotran_5 PF00266.19 KFX92716.1 - 2.6e-07 29.9 0.0 2.5e-06 26.7 0.0 1.9 1 1 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 KFX92716.1 - 0.0092 15.3 0.0 0.018 14.4 0.0 1.4 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Cys_Met_Meta_PP PF01053.20 KFX92716.1 - 0.083 11.4 0.0 0.12 10.9 0.0 1.1 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme PYC_OADA PF02436.18 KFX92719.1 - 0.016 14.9 0.2 0.026 14.3 0.2 1.5 1 0 0 1 1 1 0 Conserved carboxylase domain DUF3180 PF11377.8 KFX92719.1 - 0.03 14.5 0.4 0.051 13.7 0.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3180) Fib_alpha PF08702.10 KFX92719.1 - 0.044 14.0 0.0 0.92 9.7 0.0 2.1 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family Glutaredoxin PF00462.24 KFX92720.1 - 4.3e-13 49.3 0.0 5.9e-13 48.8 0.0 1.2 1 0 0 1 1 1 1 Glutaredoxin RNase_PH_C PF03725.15 KFX92740.1 - 4.9e-10 39.3 0.0 8e-10 38.6 0.0 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 RNase_PH PF01138.21 KFX92740.1 - 1.3e-06 28.9 1.2 1.6e-06 28.6 0.1 1.8 2 1 0 2 2 2 1 3' exoribonuclease family, domain 1 HEAT PF02985.22 KFX92741.1 - 2e-09 36.9 0.3 0.11 12.8 0.0 5.3 4 0 0 4 4 4 3 HEAT repeat HEAT_2 PF13646.6 KFX92741.1 - 2.5e-05 24.6 1.7 0.006 16.9 0.1 4.5 4 0 0 4 4 4 1 HEAT repeats Iso_dh PF00180.20 KFX92746.1 - 1.9e-83 280.5 0.0 2.4e-83 280.2 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Proteasome PF00227.26 KFX92747.1 - 7.5e-46 156.0 0.1 9.9e-32 110.0 0.0 2.1 2 0 0 2 2 2 2 Proteasome subunit Proteasome_A_N PF10584.9 KFX92747.1 - 3.2e-11 42.7 0.0 3.2e-11 42.7 0.0 1.6 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature Trs65 PF12735.7 KFX92750.1 - 2.2e-62 211.3 0.1 3.1e-62 210.8 0.1 1.2 1 0 0 1 1 1 1 TRAPP trafficking subunit Trs65 FF PF01846.19 KFX92751.1 - 2e-50 168.8 14.3 2.8e-15 56.2 0.7 6.7 6 0 0 6 6 6 5 FF domain WW PF00397.26 KFX92751.1 - 8.2e-17 61.0 14.0 1.5e-09 37.8 1.5 2.6 2 0 0 2 2 2 2 WW domain HycH PF07450.11 KFX92751.1 - 0.2 12.0 0.2 0.54 10.6 0.2 1.7 1 0 0 1 1 1 0 Formate hydrogenlyase maturation protein HycH Glyco_hyd_101C PF17451.2 KFX92751.1 - 0.29 11.4 5.6 5.4 7.3 0.2 2.7 1 1 1 2 2 2 0 Glycosyl hydrolase 101 beta sandwich domain ABC_tran PF00005.27 KFX92752.1 - 1.8e-33 115.9 0.0 2.8e-15 57.0 0.0 2.6 2 1 0 2 2 2 2 ABC transporter RLI PF04068.15 KFX92752.1 - 9e-14 51.0 5.1 9e-14 51.0 5.1 2.0 2 0 0 2 2 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI SMC_N PF02463.19 KFX92752.1 - 6.2e-11 42.1 1.9 0.0021 17.6 0.0 3.7 2 2 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 KFX92752.1 - 9.7e-10 38.7 5.7 0.089 12.6 0.9 4.5 3 2 2 5 5 4 4 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 KFX92752.1 - 1.6e-05 24.8 0.2 0.22 11.2 0.0 3.3 3 1 1 4 4 4 2 AAA ATPase domain AAA_16 PF13191.6 KFX92752.1 - 5.5e-05 23.6 0.0 0.22 11.9 0.0 2.4 2 0 0 2 2 2 2 AAA ATPase domain AAA PF00004.29 KFX92752.1 - 6e-05 23.5 0.1 0.059 13.8 0.1 2.7 3 0 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) Fer4 PF00037.27 KFX92752.1 - 6.4e-05 22.6 3.2 6.4e-05 22.6 3.2 2.8 3 0 0 3 3 3 1 4Fe-4S binding domain AAA_22 PF13401.6 KFX92752.1 - 7.8e-05 23.0 0.0 0.016 15.5 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_24 PF13479.6 KFX92752.1 - 0.00023 20.9 0.1 0.064 13.0 0.0 2.5 2 0 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 KFX92752.1 - 0.00028 20.8 0.1 0.88 9.4 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase Rad17 PF03215.15 KFX92752.1 - 0.00038 20.4 0.0 0.021 14.7 0.0 2.5 2 0 0 2 2 2 1 Rad17 P-loop domain AAA_29 PF13555.6 KFX92752.1 - 0.00063 19.4 0.2 0.62 9.8 0.0 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_23 PF13476.6 KFX92752.1 - 0.0011 19.6 0.1 0.18 12.3 0.1 2.5 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 KFX92752.1 - 0.0011 19.5 0.1 2.7 8.6 0.0 3.0 3 1 0 3 3 3 1 AAA domain Fer4_21 PF14697.6 KFX92752.1 - 0.0015 18.6 11.7 0.0036 17.4 11.7 1.7 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_6 PF12837.7 KFX92752.1 - 0.002 18.1 12.5 0.0042 17.1 2.1 2.5 2 0 0 2 2 2 1 4Fe-4S binding domain RNA_helicase PF00910.22 KFX92752.1 - 0.0025 18.2 1.0 0.68 10.3 0.1 2.8 3 0 0 3 3 2 1 RNA helicase Thymidylate_kin PF02223.17 KFX92752.1 - 0.0037 17.0 1.9 5 6.8 0.0 3.3 3 0 0 3 3 3 0 Thymidylate kinase AAA_13 PF13166.6 KFX92752.1 - 0.0046 15.7 0.4 0.011 14.4 0.0 1.8 2 0 0 2 2 2 1 AAA domain Fer4_10 PF13237.6 KFX92752.1 - 0.0054 16.8 15.1 0.021 14.9 1.5 2.4 1 1 1 2 2 2 1 4Fe-4S dicluster domain TsaE PF02367.17 KFX92752.1 - 0.011 15.7 0.1 0.14 12.1 0.0 2.3 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE NACHT PF05729.12 KFX92752.1 - 0.012 15.5 1.8 0.73 9.7 0.1 2.5 2 0 0 2 2 2 0 NACHT domain SRP54 PF00448.22 KFX92752.1 - 0.017 14.7 5.0 0.12 12.0 0.4 2.3 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain NB-ARC PF00931.22 KFX92752.1 - 0.023 13.9 0.0 2.2 7.4 0.0 2.4 2 0 0 2 2 2 0 NB-ARC domain AAA_33 PF13671.6 KFX92752.1 - 0.025 14.7 1.2 1.4 9.1 0.1 2.4 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.6 KFX92752.1 - 0.029 14.6 0.3 3.5 7.9 0.0 2.4 2 0 0 2 2 2 0 AAA domain Fer4_9 PF13187.6 KFX92752.1 - 0.04 14.1 11.2 0.088 13.0 11.2 1.6 1 0 0 1 1 1 0 4Fe-4S dicluster domain AAA_30 PF13604.6 KFX92752.1 - 0.041 13.6 0.4 2.7 7.7 0.0 2.4 2 0 0 2 2 2 0 AAA domain Fer4_7 PF12838.7 KFX92752.1 - 0.049 14.2 1.5 0.049 14.2 1.5 2.4 1 1 2 3 3 3 0 4Fe-4S dicluster domain Fer4_16 PF13484.6 KFX92752.1 - 0.071 14.1 0.2 0.071 14.1 0.2 2.6 2 0 0 2 2 2 0 4Fe-4S double cluster binding domain AAA_5 PF07728.14 KFX92752.1 - 0.084 12.9 0.2 3.1 7.8 0.0 2.5 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) VirE PF05272.11 KFX92752.1 - 0.095 12.4 0.0 7 6.3 0.0 2.3 2 0 0 2 2 2 0 Virulence-associated protein E Fer4_17 PF13534.6 KFX92752.1 - 0.12 12.9 0.2 0.12 12.9 0.2 2.4 2 0 0 2 2 2 0 4Fe-4S dicluster domain ATPase PF06745.13 KFX92752.1 - 0.16 11.3 0.1 0.37 10.1 0.1 1.6 1 0 0 1 1 1 0 KaiC AAA_7 PF12775.7 KFX92752.1 - 0.19 11.2 0.9 2.2 7.8 0.1 2.2 2 0 0 2 2 2 0 P-loop containing dynein motor region Fer4_8 PF13183.6 KFX92752.1 - 0.54 10.8 6.9 0.42 11.1 0.2 2.4 2 0 0 2 2 2 0 4Fe-4S dicluster domain NTPase_1 PF03266.15 KFX92752.1 - 1.4 8.8 3.2 15 5.5 0.2 2.7 2 0 0 2 2 2 0 NTPase PduV-EutP PF10662.9 KFX92752.1 - 1.7 8.4 5.7 0.31 10.8 0.3 2.5 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation Fer4_2 PF12797.7 KFX92752.1 - 4.2 7.7 9.7 0.66 10.2 1.3 2.6 2 0 0 2 2 2 0 4Fe-4S binding domain SNF2_N PF00176.23 KFX92753.1 - 3.6e-56 190.4 0.0 5.7e-56 189.7 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Chromo PF00385.24 KFX92753.1 - 9.8e-24 83.0 2.4 1.8e-14 53.4 0.1 3.0 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain DUF4208 PF13907.6 KFX92753.1 - 9.7e-19 67.6 1.1 2.6e-18 66.3 0.0 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF4208) Helicase_C PF00271.31 KFX92753.1 - 1.5e-18 67.1 0.0 3.9e-18 65.8 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HDA2-3 PF11496.8 KFX92753.1 - 3.9e-08 32.8 1.4 9.8e-08 31.5 0.1 2.3 2 0 0 2 2 2 1 Class II histone deacetylase complex subunits 2 and 3 Cdh1_DBD_1 PF18196.1 KFX92753.1 - 7.1e-08 32.8 4.6 1.5e-06 28.5 0.2 5.2 4 1 1 5 5 5 2 Chromodomain helicase DNA-binding domain 1 ResIII PF04851.15 KFX92753.1 - 9.3e-07 29.0 0.0 6.5e-06 26.3 0.0 2.5 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit SLIDE PF09111.10 KFX92753.1 - 0.00057 19.9 0.0 0.031 14.3 0.0 3.2 2 0 0 2 2 2 1 SLIDE CHDCT2 PF08074.11 KFX92753.1 - 0.013 15.6 0.1 0.013 15.6 0.1 3.0 3 1 1 4 4 4 0 CHDCT2 (NUC038) domain Fungal_trans_2 PF11951.8 KFX92754.1 - 3.2e-08 32.8 1.1 3.2e-08 32.8 1.1 1.8 3 0 0 3 3 3 1 Fungal specific transcription factor domain RTA1 PF04479.13 KFX92755.1 - 8.8e-73 244.3 11.0 1.2e-72 243.9 11.0 1.1 1 0 0 1 1 1 1 RTA1 like protein GST_N_2 PF13409.6 KFX92758.1 - 1.7e-07 31.4 0.1 3.9e-07 30.3 0.1 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 KFX92758.1 - 4.1e-06 27.1 0.0 9e-06 26.0 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Kp4 PF09044.10 KFX92759.1 - 7.3e-38 129.5 1.2 8.8e-38 129.2 1.2 1.1 1 0 0 1 1 1 1 Kp4 MU117 PF15474.6 KFX92759.1 - 0.057 14.2 2.6 0.11 13.3 2.6 1.5 1 1 0 1 1 1 0 Meiotically up-regulated gene family ELO PF01151.18 KFX92760.1 - 6.4e-63 212.6 20.7 7.6e-63 212.4 20.7 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family Ribosomal_L4 PF00573.22 KFX92761.1 - 9.1e-35 120.1 0.3 1.3e-34 119.6 0.3 1.2 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family Ribos_L4_asso_C PF14374.6 KFX92761.1 - 2.9e-28 97.7 1.0 4.6e-28 97.1 0.1 1.8 2 0 0 2 2 2 1 60S ribosomal protein L4 C-terminal domain HDA2-3 PF11496.8 KFX92762.1 - 2.3e-13 50.0 0.0 5.1e-12 45.5 0.0 2.4 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 DUF4196 PF13846.6 KFX92762.1 - 0.0048 17.1 0.6 0.026 14.7 0.6 2.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4196) HMMR_N PF15905.5 KFX92762.1 - 0.025 14.0 29.5 0.05 13.1 29.5 1.4 1 0 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal MAD PF05557.13 KFX92762.1 - 0.31 9.4 37.8 0.88 7.9 10.2 2.2 1 1 1 2 2 2 0 Mitotic checkpoint protein FPP PF05911.11 KFX92762.1 - 0.43 8.7 33.5 1.1 7.4 16.2 2.3 1 1 1 2 2 2 0 Filament-like plant protein, long coiled-coil AT_hook PF02178.19 KFX92762.1 - 2.6 8.2 26.7 0.054 13.4 3.1 3.7 3 0 0 3 3 3 0 AT hook motif Pox_A_type_inc PF04508.12 KFX92762.1 - 6.9 6.7 6.6 6.4 6.8 1.2 3.6 3 0 0 3 3 3 0 Viral A-type inclusion protein repeat COX5A PF02284.16 KFX92763.1 - 4.3e-41 139.1 0.6 5.4e-41 138.8 0.6 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Va Clr5 PF14420.6 KFX92770.1 - 2.7e-17 62.7 4.2 5.5e-17 61.7 4.2 1.5 1 0 0 1 1 1 1 Clr5 domain Ank_2 PF12796.7 KFX92771.1 - 6.7e-101 331.0 26.6 4.2e-16 59.3 0.1 11.3 3 1 6 11 11 11 11 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KFX92771.1 - 1.3e-73 242.5 16.5 3.5e-08 33.8 0.0 17.3 3 3 18 21 21 21 19 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFX92771.1 - 5.3e-71 226.1 24.5 0.0023 18.3 0.0 22.1 24 0 0 24 24 24 16 Ankyrin repeat Ank PF00023.30 KFX92771.1 - 8.1e-57 187.3 40.8 4.2e-05 23.8 0.1 21.0 22 0 0 22 22 22 16 Ankyrin repeat Ank_5 PF13857.6 KFX92771.1 - 8e-39 131.2 28.2 0.0021 18.3 0.0 16.5 8 5 10 18 18 18 13 Ankyrin repeats (many copies) DUF484 PF04340.12 KFX92771.1 - 0.15 11.7 1.2 11 5.6 0.2 2.5 2 0 0 2 2 2 0 Protein of unknown function, DUF484 COesterase PF00135.28 KFX92774.1 - 4.3e-52 177.6 0.0 4.9e-52 177.5 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KFX92774.1 - 0.002 18.0 0.1 0.026 14.4 0.0 2.3 2 0 0 2 2 2 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KFX92774.1 - 0.0077 15.7 0.0 0.012 15.1 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Glyco_hydro_61 PF03443.14 KFX92782.1 - 5.7e-59 199.5 0.0 8.1e-59 199.0 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Coatomer_E PF04733.14 KFX92784.1 - 4.9e-63 213.2 8.9 6.6e-63 212.8 8.9 1.1 1 0 0 1 1 1 1 Coatomer epsilon subunit TPR_19 PF14559.6 KFX92784.1 - 1.9e-10 41.1 25.6 1.3e-05 25.6 0.4 4.4 3 1 3 6 6 5 3 Tetratricopeptide repeat TPR_14 PF13428.6 KFX92784.1 - 2e-07 31.3 20.4 8e-05 23.2 0.2 5.9 4 2 2 6 6 5 2 Tetratricopeptide repeat ANAPC3 PF12895.7 KFX92784.1 - 3.9e-07 30.2 4.1 0.01 16.0 0.3 3.5 3 0 0 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.6 KFX92784.1 - 2.8e-06 27.9 22.4 0.017 15.7 0.1 5.0 2 2 2 4 4 4 2 Tetratricopeptide repeat SRP_TPR_like PF17004.5 KFX92784.1 - 6.4e-05 22.9 0.7 0.003 17.5 0.1 2.6 2 1 0 2 2 2 1 Putative TPR-like repeat TPR_1 PF00515.28 KFX92784.1 - 9.5e-05 22.1 0.9 0.0094 15.7 0.0 4.0 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_11 PF13414.6 KFX92784.1 - 0.00016 21.3 0.1 0.012 15.3 0.0 3.3 2 0 0 2 2 2 1 TPR repeat TPR_12 PF13424.6 KFX92784.1 - 0.00019 21.7 16.2 0.11 12.8 0.1 4.6 3 2 2 5 5 5 3 Tetratricopeptide repeat TPR_8 PF13181.6 KFX92784.1 - 0.00021 21.2 6.0 0.58 10.5 0.0 4.9 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_6 PF13174.6 KFX92784.1 - 0.00039 20.9 8.5 0.013 16.1 0.0 5.4 6 0 0 6 6 5 1 Tetratricopeptide repeat TPR_2 PF07719.17 KFX92784.1 - 0.0017 18.3 0.0 0.0017 18.3 0.0 6.2 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_4 PF07721.14 KFX92784.1 - 0.009 16.5 14.8 0.73 10.6 0.3 5.6 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_17 PF13431.6 KFX92784.1 - 0.015 15.7 0.2 0.28 11.7 0.0 3.2 3 1 0 3 3 2 0 Tetratricopeptide repeat Tcf25 PF04910.14 KFX92784.1 - 0.053 12.6 0.3 0.064 12.3 0.3 1.2 1 0 0 1 1 1 0 Transcriptional repressor TCF25 TPR_9 PF13371.6 KFX92784.1 - 3.1 8.0 7.4 2.1 8.6 0.1 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat HAD PF12710.7 KFX92785.1 - 4.4e-24 85.9 0.0 6e-24 85.5 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Put_Phosphatase PF06888.12 KFX92785.1 - 0.0035 16.8 0.0 0.046 13.1 0.0 2.3 2 1 0 2 2 2 1 Putative Phosphatase UMPH-1 PF05822.12 KFX92785.1 - 0.03 13.9 0.0 0.078 12.5 0.0 1.7 2 0 0 2 2 2 0 Pyrimidine 5'-nucleotidase (UMPH-1) Hydrolase PF00702.26 KFX92785.1 - 0.032 14.5 0.1 0.13 12.5 0.0 2.0 1 1 0 2 2 2 0 haloacid dehalogenase-like hydrolase Herpes_US12 PF05363.12 KFX92785.1 - 0.039 14.7 0.1 13 6.6 0.0 3.0 3 0 0 3 3 3 0 Herpesvirus US12 family Herpes_teg_N PF04843.12 KFX92785.1 - 0.11 12.1 0.0 9.3 5.9 0.0 2.6 3 0 0 3 3 3 0 Herpesvirus tegument protein, N-terminal conserved region Lipase_GDSL_2 PF13472.6 KFX92786.1 - 4.4e-10 40.2 0.4 1.6e-08 35.1 0.4 2.3 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Glyco_hydro_99 PF16317.5 KFX92786.1 - 0.00089 18.5 0.0 0.0015 17.7 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 99 Lipase_GDSL PF00657.22 KFX92786.1 - 0.0025 17.8 0.0 0.0048 16.9 0.0 1.5 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase DUF4992 PF16383.5 KFX92786.1 - 0.13 11.8 0.1 0.97 8.9 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function TrbI PF03743.14 KFX92787.1 - 0.0022 17.9 0.5 0.0035 17.2 0.5 1.2 1 0 0 1 1 1 1 Bacterial conjugation TrbI-like protein LIDHydrolase PF10230.9 KFX92789.1 - 2.4e-46 158.5 0.0 3.4e-46 158.0 0.0 1.2 1 0 0 1 1 1 1 Lipid-droplet associated hydrolase Abhydrolase_6 PF12697.7 KFX92789.1 - 3.3e-05 24.6 1.2 3.3e-05 24.6 1.2 1.8 2 0 0 2 2 2 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KFX92789.1 - 0.016 14.5 0.0 0.078 12.2 0.0 2.0 1 1 0 1 1 1 0 Serine aminopeptidase, S33 Peptidase_M28 PF04389.17 KFX92790.1 - 5.9e-28 97.9 0.0 1.1e-27 97.0 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.22 KFX92790.1 - 3.8e-10 39.6 0.1 7.8e-10 38.6 0.1 1.5 1 0 0 1 1 1 1 PA domain Kp4 PF09044.10 KFX92791.1 - 7.9e-65 216.6 13.1 2.2e-36 124.7 4.7 2.0 2 0 0 2 2 2 2 Kp4 MU117 PF15474.6 KFX92791.1 - 0.00019 22.1 9.0 0.05 14.4 2.2 2.4 2 1 0 2 2 2 2 Meiotically up-regulated gene family Beta-TrCP_D PF12125.8 KFX92791.1 - 0.078 12.9 0.1 7.4 6.5 0.0 2.4 2 0 0 2 2 2 0 D domain of beta-TrCP zf-ribbon_3 PF13248.6 KFX92791.1 - 0.14 11.6 6.2 0.39 10.2 0.8 2.7 2 0 0 2 2 2 0 zinc-ribbon domain GGACT PF06094.12 KFX92792.1 - 2e-05 25.2 0.0 2.9e-05 24.7 0.0 1.2 1 0 0 1 1 1 1 Gamma-glutamyl cyclotransferase, AIG2-like DUF4407 PF14362.6 KFX92793.1 - 0.096 12.0 2.4 0.16 11.3 2.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) ZapB PF06005.12 KFX92793.1 - 0.14 12.7 4.9 4.8 7.7 1.2 2.9 3 0 0 3 3 3 0 Cell division protein ZapB Seryl_tRNA_N PF02403.22 KFX92793.1 - 0.16 12.2 1.1 1.2 9.3 0.5 2.2 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Spc7 PF08317.11 KFX92793.1 - 0.3 9.9 3.0 0.27 10.1 1.5 1.6 2 0 0 2 2 2 0 Spc7 kinetochore protein TPR_MLP1_2 PF07926.12 KFX92793.1 - 0.78 9.8 6.6 7.8 6.6 5.4 2.3 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein DivIC PF04977.15 KFX92793.1 - 0.82 9.5 3.2 18 5.2 0.1 2.3 2 0 0 2 2 2 0 Septum formation initiator TMF_TATA_bd PF12325.8 KFX92793.1 - 3.5 7.9 6.0 3.3 8.0 2.8 2.3 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding Transp_cyt_pur PF02133.15 KFX92799.1 - 4.9e-142 473.8 34.3 5.6e-142 473.6 34.3 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin SurE PF01975.17 KFX92800.1 - 1.9e-38 132.2 0.0 2.7e-38 131.7 0.0 1.2 1 0 0 1 1 1 1 Survival protein SurE Aldedh PF00171.22 KFX92801.1 - 5.3e-116 387.9 1.8 8.5e-113 377.3 0.4 2.1 2 0 0 2 2 2 2 Aldehyde dehydrogenase family MFS_1 PF07690.16 KFX92801.1 - 7.3e-16 58.0 45.3 7.3e-16 58.0 45.3 1.9 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KFX92801.1 - 0.001 18.1 13.7 0.001 18.1 13.7 2.3 2 0 0 2 2 2 1 Sugar (and other) transporter UPF0093 PF03653.13 KFX92801.1 - 0.052 13.8 6.2 0.12 12.6 6.2 1.6 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0093) ThrE PF06738.12 KFX92806.1 - 2.9e-74 249.5 16.7 1.2e-70 237.7 1.5 2.6 3 0 0 3 3 3 2 Putative threonine/serine exporter ThrE_2 PF12821.7 KFX92806.1 - 1.4e-12 47.9 6.6 1.4e-12 47.9 6.6 2.6 2 0 0 2 2 2 1 Threonine/Serine exporter, ThrE E1-E2_ATPase PF00122.20 KFX92806.1 - 1.2 8.7 3.4 0.79 9.2 1.0 1.9 2 0 0 2 2 2 0 E1-E2 ATPase Aldedh PF00171.22 KFX92807.1 - 3.6e-160 533.5 0.3 4.1e-160 533.3 0.3 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Wtap PF17098.5 KFX92807.1 - 0.0067 16.4 0.0 0.013 15.4 0.0 1.4 1 0 0 1 1 1 1 WTAP/Mum2p family GMC_oxred_N PF00732.19 KFX92808.1 - 8.6e-50 169.8 0.0 1.2e-49 169.3 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KFX92808.1 - 9.8e-37 126.7 0.0 1.6e-36 126.0 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.6 KFX92808.1 - 0.00015 21.9 0.1 0.0012 19.1 0.1 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 KFX92808.1 - 0.00016 20.9 0.1 0.00028 20.0 0.0 1.4 2 0 0 2 2 2 1 Lycopene cyclase protein FAD_binding_2 PF00890.24 KFX92808.1 - 0.0003 20.0 0.0 0.11 11.5 0.0 2.4 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.24 KFX92808.1 - 0.002 17.8 0.3 0.01 15.4 0.1 2.2 3 0 0 3 3 3 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 KFX92808.1 - 0.0025 18.3 0.1 0.94 10.1 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KFX92808.1 - 0.0029 16.9 0.0 0.0091 15.3 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KFX92808.1 - 0.03 13.6 0.0 0.55 9.4 0.0 2.7 3 0 0 3 3 3 0 Thi4 family FAD_oxidored PF12831.7 KFX92808.1 - 0.047 13.0 0.1 2.1 7.6 0.0 2.3 2 1 0 2 2 2 0 FAD dependent oxidoreductase Trp_halogenase PF04820.14 KFX92808.1 - 0.14 11.0 0.0 0.19 10.6 0.0 1.1 1 0 0 1 1 1 0 Tryptophan halogenase adh_short PF00106.25 KFX92809.1 - 1.6e-37 128.9 0.6 2e-37 128.5 0.6 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KFX92809.1 - 8.9e-33 113.8 0.1 1.5e-32 113.0 0.1 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KFX92809.1 - 3.7e-10 40.0 0.4 6.4e-10 39.2 0.4 1.3 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.10 KFX92809.1 - 0.00098 18.6 0.0 0.0017 17.8 0.0 1.3 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) ADH_zinc_N PF00107.26 KFX92809.1 - 0.0012 18.9 0.2 0.0022 18.0 0.2 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase NAD_binding_7 PF13241.6 KFX92809.1 - 0.0038 17.6 0.0 0.009 16.4 0.0 1.6 2 0 0 2 2 2 1 Putative NAD(P)-binding Polysacc_synt_2 PF02719.15 KFX92809.1 - 0.02 14.1 0.1 0.026 13.7 0.1 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Sigma54_activ_2 PF14532.6 KFX92809.1 - 0.066 13.3 0.0 0.14 12.3 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain FAD_binding_3 PF01494.19 KFX92809.1 - 0.086 12.1 0.2 0.14 11.4 0.2 1.3 1 0 0 1 1 1 0 FAD binding domain HTHP PF11534.8 KFX92809.1 - 0.17 12.3 0.1 1.6 9.2 0.0 2.2 2 0 0 2 2 2 0 Hexameric tyrosine-coordinated heme protein (HTHP) Fungal_trans PF04082.18 KFX92816.1 - 1.1e-06 27.9 0.3 4e-06 26.0 0.0 1.9 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KFX92816.1 - 2.3e-06 27.6 10.0 4.8e-06 26.6 10.0 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Xpo1 PF08389.12 KFX92817.1 - 4.9e-29 101.3 1.0 4.9e-29 101.3 1.0 2.8 3 0 0 3 3 3 1 Exportin 1-like protein IBN_N PF03810.19 KFX92817.1 - 3.3e-09 36.5 0.1 9.5e-08 31.9 0.0 2.6 2 0 0 2 2 2 1 Importin-beta N-terminal domain UME PF08064.13 KFX92817.1 - 0.0027 17.6 1.3 0.44 10.5 0.0 4.0 3 0 0 3 3 3 1 UME (NUC010) domain Adaptin_N PF01602.20 KFX92817.1 - 0.09 11.3 0.3 9.4 4.7 0.1 2.3 2 0 0 2 2 2 0 Adaptin N terminal region TIM21 PF08294.11 KFX92818.1 - 4.1e-40 137.0 0.0 5e-40 136.7 0.0 1.1 1 0 0 1 1 1 1 TIM21 Coa1 PF08695.10 KFX92818.1 - 1.2e-06 28.2 0.0 2.7e-06 27.1 0.0 1.5 1 1 0 1 1 1 1 Cytochrome oxidase complex assembly protein 1 Sec5 PF15469.6 KFX92833.1 - 0.07 12.9 0.1 0.12 12.1 0.1 1.3 1 0 0 1 1 1 0 Exocyst complex component Sec5 Sec39 PF08314.11 KFX92848.1 - 1.5e-23 83.2 1.2 1.8e-23 83.0 1.2 1.1 1 0 0 1 1 1 1 Secretory pathway protein Sec39 Fungal_trans_2 PF11951.8 KFX92854.1 - 4.9e-25 88.1 2.7 1.5e-24 86.6 2.7 1.7 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KFX92854.1 - 3.2e-07 30.3 6.7 7.2e-07 29.2 6.7 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain LCE PF14672.6 KFX92854.1 - 8.9 7.0 10.6 0.65 10.6 4.5 2.4 2 0 0 2 2 2 0 Late cornified envelope OrsD PF12013.8 KFX92855.1 - 6.6e-06 26.5 0.4 1.9e-05 25.1 0.3 1.8 1 1 1 2 2 2 1 Orsellinic acid/F9775 biosynthesis cluster protein D zf-C2H2_2 PF12756.7 KFX92855.1 - 0.046 14.1 0.4 3 8.2 0.0 2.3 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) Glyco_trans_1_3 PF13528.6 KFX92855.1 - 0.34 10.1 0.4 0.52 9.5 0.4 1.2 1 0 0 1 1 1 0 Glycosyl transferase family 1 zf-Di19 PF05605.12 KFX92855.1 - 0.59 10.5 3.5 2.5 8.4 1.0 2.3 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding AMP-binding PF00501.28 KFX92862.1 - 1.4e-89 300.6 0.4 1.8e-89 300.3 0.4 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KFX92862.1 - 1.7e-26 93.0 0.1 2.9e-25 89.0 0.2 2.6 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain ACAS_N PF16177.5 KFX92862.1 - 1.6e-18 66.4 1.5 4.5e-18 64.9 1.5 1.9 1 0 0 1 1 1 1 Acetyl-coenzyme A synthetase N-terminus NMDAR2_C PF10565.9 KFX92862.1 - 0.14 11.0 0.1 0.21 10.5 0.1 1.1 1 0 0 1 1 1 0 N-methyl D-aspartate receptor 2B3 C-terminus C1_2 PF03107.16 KFX92865.1 - 0.18 12.2 0.9 28 5.1 0.2 2.7 2 0 0 2 2 2 0 C1 domain Fungal_trans PF04082.18 KFX92868.1 - 8e-09 34.9 0.0 8e-09 34.9 0.0 2.5 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KFX92868.1 - 1.2e-06 28.6 8.5 2.3e-06 27.6 8.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Aminotran_5 PF00266.19 KFX92869.1 - 1.9e-27 96.2 0.0 2.3e-27 95.9 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V GTP1_OBG PF01018.22 KFX92887.1 - 8.8e-39 132.6 5.6 3.4e-29 101.4 5.4 2.3 2 0 0 2 2 2 2 GTP1/OBG MMR_HSR1 PF01926.23 KFX92887.1 - 5.2e-23 81.3 0.0 9.1e-23 80.5 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 KFX92887.1 - 1.9e-07 30.7 0.1 4.6e-07 29.5 0.1 1.7 1 1 0 1 1 1 1 Ferrous iron transport protein B ABC_tran PF00005.27 KFX92887.1 - 0.18 12.3 1.1 0.33 11.5 0.0 1.9 2 0 0 2 2 2 0 ABC transporter CENP-F_leu_zip PF10473.9 KFX92889.1 - 0.00043 20.3 12.4 0.00043 20.3 12.4 4.2 2 2 0 3 3 3 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 ABC_tran_CTD PF16326.5 KFX92889.1 - 0.047 13.9 0.3 0.047 13.9 0.3 5.5 4 1 1 5 5 5 0 ABC transporter C-terminal domain Propeptide_C1 PF08127.13 KFX92889.1 - 0.11 12.4 0.1 3.3 7.7 0.0 2.5 2 0 0 2 2 2 0 Peptidase family C1 propeptide FlaC_arch PF05377.11 KFX92889.1 - 5.1 7.6 11.6 33 5.0 0.1 5.0 4 2 2 6 6 6 0 Flagella accessory protein C (FlaC) DUF4239 PF14023.6 KFX92889.1 - 9.4 5.9 6.5 2.9 7.6 0.5 2.5 1 1 0 2 2 2 0 Protein of unknown function (DUF4239) DEAD PF00270.29 KFX92890.1 - 8.7e-44 149.4 0.0 1.5e-43 148.6 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase RNA_pol_Rpb5_C PF01191.19 KFX92890.1 - 1.9e-31 107.7 0.1 5.8e-31 106.2 0.1 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb5, C-terminal domain RNA_pol_Rpb5_N PF03871.14 KFX92890.1 - 8.7e-27 93.5 0.0 1.7e-26 92.6 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb5, N-terminal domain Helicase_C PF00271.31 KFX92890.1 - 5.9e-21 74.9 0.0 1.1e-19 70.8 0.0 3.0 4 0 0 4 4 4 1 Helicase conserved C-terminal domain ResIII PF04851.15 KFX92890.1 - 4.4e-05 23.6 0.0 7.2e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Mrr_cat PF04471.12 KFX92890.1 - 0.046 13.8 0.1 0.17 11.9 0.0 1.9 2 0 0 2 2 2 0 Restriction endonuclease SecA_DEAD PF07517.14 KFX92890.1 - 0.14 11.4 0.1 1.8 7.8 0.0 2.3 3 0 0 3 3 3 0 SecA DEAD-like domain BTB PF00651.31 KFX92891.1 - 8e-18 64.7 0.2 1.3e-07 31.8 0.0 3.0 3 0 0 3 3 3 2 BTB/POZ domain WD40 PF00400.32 KFX92891.1 - 4.2e-15 55.9 15.9 0.029 15.2 0.0 7.0 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFX92891.1 - 0.067 13.5 0.1 2.3 8.6 0.0 3.2 2 1 2 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain Cation_efflux PF01545.21 KFX92902.1 - 8.3e-47 159.5 2.2 1.1e-46 159.1 2.2 1.2 1 0 0 1 1 1 1 Cation efflux family Zip PF02535.22 KFX92902.1 - 1.1 8.4 35.6 0.0099 15.1 16.9 2.9 1 1 1 2 2 2 0 ZIP Zinc transporter Mito_carr PF00153.27 KFX92904.1 - 5.7e-55 183.2 7.0 1.6e-18 66.4 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Ras PF00071.22 KFX92918.1 - 1.7e-65 219.6 0.5 2e-65 219.3 0.5 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFX92918.1 - 6.6e-36 123.2 0.1 1.2e-35 122.3 0.1 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFX92918.1 - 3e-16 59.4 0.1 3.6e-16 59.1 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 KFX92918.1 - 1.8e-05 24.8 0.1 9.6e-05 22.4 0.0 2.0 1 1 1 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KFX92918.1 - 2.2e-05 24.4 0.3 0.13 12.2 0.0 2.3 1 1 1 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 KFX92918.1 - 8.2e-05 22.2 0.4 0.00023 20.8 0.2 1.8 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 KFX92918.1 - 0.00026 20.4 0.1 0.00033 20.1 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 KFX92918.1 - 0.00045 19.7 0.0 0.00069 19.1 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA PF00004.29 KFX92918.1 - 0.00082 19.8 0.1 0.16 12.4 0.0 2.2 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) FeoB_N PF02421.18 KFX92918.1 - 0.0042 16.6 0.0 0.025 14.1 0.0 1.9 1 1 0 1 1 1 1 Ferrous iron transport protein B AAA_16 PF13191.6 KFX92918.1 - 0.0081 16.6 0.0 0.011 16.1 0.0 1.4 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 KFX92918.1 - 0.036 14.4 0.0 0.067 13.5 0.0 1.8 1 1 0 1 1 1 0 AAA domain AAA_29 PF13555.6 KFX92918.1 - 0.052 13.3 0.0 0.15 11.8 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_5 PF07728.14 KFX92918.1 - 0.068 13.2 0.0 0.13 12.3 0.0 1.7 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) TniB PF05621.11 KFX92918.1 - 0.072 12.5 0.0 0.21 11.0 0.0 1.7 2 0 0 2 2 2 0 Bacterial TniB protein Septin PF00735.18 KFX92918.1 - 0.075 12.3 0.0 0.18 11.1 0.0 1.6 2 0 0 2 2 2 0 Septin ABC_tran PF00005.27 KFX92918.1 - 0.076 13.5 0.1 0.15 12.6 0.1 1.7 1 1 0 1 1 1 0 ABC transporter AAA_7 PF12775.7 KFX92918.1 - 0.084 12.4 0.0 0.18 11.3 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region PduV-EutP PF10662.9 KFX92918.1 - 0.1 12.4 0.1 0.65 9.7 0.1 2.2 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_25 PF13481.6 KFX92918.1 - 0.12 11.9 0.1 1.5 8.3 0.0 2.2 2 1 0 2 2 2 0 AAA domain Pyr_redox_2 PF07992.14 KFX92927.1 - 2.2e-58 197.8 3.5 3.8e-58 197.1 3.5 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 KFX92927.1 - 6e-34 116.6 0.1 1.6e-32 112.0 0.1 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 KFX92927.1 - 1.3e-17 64.1 1.4 1.5e-16 60.7 0.0 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KFX92927.1 - 6.3e-14 51.9 0.7 1e-13 51.2 0.7 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Methyltransf_23 PF13489.6 KFX92927.1 - 1.3e-10 41.3 0.0 2.7e-10 40.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KFX92927.1 - 3.1e-10 40.6 0.0 9.2e-10 39.1 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KFX92927.1 - 1.4e-08 35.4 0.0 4e-08 33.9 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KFX92927.1 - 3.8e-07 30.0 0.0 8.3e-07 28.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KFX92927.1 - 8.5e-07 29.7 1.0 1.4e-06 29.0 0.0 2.0 2 0 0 2 2 1 1 Methyltransferase domain K_oxygenase PF13434.6 KFX92927.1 - 0.0022 17.2 0.0 0.0044 16.2 0.0 1.5 1 0 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) FAD_oxidored PF12831.7 KFX92927.1 - 0.022 14.1 0.4 0.032 13.6 0.4 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KFX92927.1 - 0.024 13.7 3.7 0.3 10.1 1.7 2.8 3 0 0 3 3 3 0 FAD binding domain 2-Hacid_dh_C PF02826.19 KFX92927.1 - 0.027 13.9 0.1 2.4 7.5 0.0 2.5 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Thi4 PF01946.17 KFX92927.1 - 0.029 13.6 0.1 0.056 12.7 0.1 1.5 1 0 0 1 1 1 0 Thi4 family AlaDh_PNT_C PF01262.21 KFX92927.1 - 0.045 13.1 0.4 1.8 7.8 0.4 2.3 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain DUF3029 PF11230.8 KFX92927.1 - 0.12 10.7 0.0 0.2 10.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3029) GIDA PF01134.22 KFX92927.1 - 0.18 10.9 1.3 0.49 9.4 1.1 1.8 2 0 0 2 2 2 0 Glucose inhibited division protein A NAD_binding_8 PF13450.6 KFX92927.1 - 0.2 11.9 2.2 0.61 10.4 2.2 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 KFX92927.1 - 0.35 9.5 4.9 3.4 6.3 0.9 3.1 2 1 1 3 3 3 0 HI0933-like protein Helicase_C PF00271.31 KFX92928.1 - 8.5e-15 55.1 0.0 2.6e-14 53.5 0.0 1.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain RecQ_Zn_bind PF16124.5 KFX92928.1 - 3.1e-10 40.6 3.2 8.1e-10 39.3 3.2 1.7 1 0 0 1 1 1 1 RecQ zinc-binding PrlF_antitoxin PF15937.5 KFX92928.1 - 0.094 13.2 0.1 0.17 12.3 0.1 1.4 1 0 0 1 1 1 0 prlF antitoxin for toxin YhaV_toxin zf-RRPl_C4 PF17026.5 KFX92929.1 - 0.0081 16.3 3.3 0.12 12.5 0.1 2.6 1 1 1 2 2 2 1 Putative ribonucleoprotein zinc-finger pf C4 type zinc_ribbon_15 PF17032.5 KFX92929.1 - 0.064 14.0 5.3 4.2 8.2 0.8 2.5 2 0 0 2 2 2 0 zinc-ribbon family IQCJ-SCHIP1 PF15157.6 KFX92929.1 - 0.064 13.1 5.0 1.6 8.6 0.1 2.5 2 0 0 2 2 2 0 Fusion protein IQCJ-SCHIP1 with IQ-like motif DZR PF12773.7 KFX92929.1 - 0.32 11.0 7.2 2.5 8.2 0.9 2.5 2 0 0 2 2 2 0 Double zinc ribbon FYVE PF01363.21 KFX92929.1 - 2.4 8.4 8.1 1.2e+02 2.9 8.1 2.7 1 1 0 1 1 1 0 FYVE zinc finger Nudix_N_2 PF14803.6 KFX92929.1 - 9.7 6.2 7.3 48 4.0 0.0 3.7 3 1 0 3 3 3 0 Nudix N-terminal Leucyl-specific PF14795.6 KFX92932.1 - 0.041 14.0 0.0 0.11 12.6 0.0 1.7 1 0 0 1 1 1 0 Leucine-tRNA synthetase-specific domain YopE_N PF09020.10 KFX92962.1 - 0.039 14.2 2.3 0.95 9.7 0.2 2.4 2 0 0 2 2 2 0 YopE, N terminal Peptidase_M28 PF04389.17 KFX92963.1 - 2.8e-32 112.0 0.0 3.8e-32 111.6 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M28 DUF3533 PF12051.8 KFX92964.1 - 9.5e-91 304.5 7.4 1.3e-90 304.1 7.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3533) APH PF01636.23 KFX92964.1 - 2.3e-06 27.7 0.1 1.5e-05 25.1 0.0 2.3 2 1 0 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KFX92964.1 - 0.0069 16.0 0.0 0.021 14.4 0.0 1.7 2 0 0 2 2 2 1 Choline/ethanolamine kinase DUF2458 PF10454.9 KFX92980.1 - 1.1e-46 158.7 0.0 1.7e-46 158.0 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2458) NADHdh_A3 PF14987.6 KFX92980.1 - 3.3 8.1 6.9 6.4 7.2 5.2 2.1 1 1 1 2 2 2 0 NADH dehydrogenase 1 alpha subcomplex subunit 3 DUF5337 PF17272.2 KFX92983.1 - 0.0035 17.1 2.8 0.0035 17.1 2.8 2.6 3 0 0 3 3 3 1 Family of unknown function (DUF5337) PAS_3 PF08447.12 KFX92984.1 - 2.3e-15 56.7 0.0 5.1e-15 55.5 0.0 1.5 1 0 0 1 1 1 1 PAS fold GATA PF00320.27 KFX92984.1 - 3.3e-15 55.4 4.8 7.7e-15 54.2 4.8 1.7 1 0 0 1 1 1 1 GATA zinc finger PAS PF00989.25 KFX92984.1 - 1.6e-12 47.4 0.0 3.4e-12 46.4 0.0 1.5 1 0 0 1 1 1 1 PAS fold PAS_9 PF13426.7 KFX92984.1 - 1.2e-08 35.2 0.0 3.2e-08 33.8 0.0 1.8 1 0 0 1 1 1 1 PAS domain PAS_11 PF14598.6 KFX92984.1 - 1.5e-07 31.5 0.0 3.1e-07 30.5 0.0 1.5 1 0 0 1 1 1 1 PAS domain PAS_4 PF08448.10 KFX92984.1 - 3.4e-06 27.3 0.0 6e-06 26.5 0.0 1.4 1 0 0 1 1 1 1 PAS fold AAA_23 PF13476.6 KFX92985.1 - 1.8e-27 97.2 30.7 1.8e-27 97.2 30.7 6.0 1 1 2 3 3 3 1 AAA domain SMC_N PF02463.19 KFX92985.1 - 2e-07 30.7 0.0 2e-07 30.7 0.0 2.6 3 0 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 KFX92985.1 - 0.00049 19.8 0.0 0.00099 18.8 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_21 PF13304.6 KFX92985.1 - 0.00072 19.4 0.8 0.0019 18.1 0.0 2.1 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system Rad50_zn_hook PF04423.14 KFX92985.1 - 0.00081 19.2 1.2 0.00081 19.2 1.2 5.5 6 0 0 6 6 6 1 Rad50 zinc hook motif Phage_tail_T PF06223.12 KFX92985.1 - 0.02 15.4 0.3 0.19 12.2 0.1 2.6 2 0 0 2 2 2 0 Minor tail protein T AAA_16 PF13191.6 KFX92985.1 - 0.042 14.2 0.4 0.042 14.2 0.4 5.2 2 2 1 3 3 3 0 AAA ATPase domain ABC_tran PF00005.27 KFX92985.1 - 0.074 13.6 0.1 0.074 13.6 0.1 5.6 2 1 1 3 3 3 0 ABC transporter AAA_13 PF13166.6 KFX92985.1 - 0.1 11.2 0.0 0.1 11.2 0.0 5.8 2 1 4 6 6 6 0 AAA domain SMC_N PF02463.19 KFX92986.1 - 6.7e-08 32.2 0.9 8.6e-08 31.9 0.9 1.1 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain SbcCD_C PF13558.6 KFX92986.1 - 3.1e-07 30.5 0.0 7.8e-07 29.3 0.0 1.7 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit AAA_21 PF13304.6 KFX92986.1 - 2.2e-05 24.4 3.6 0.00041 20.3 3.6 2.2 1 1 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system IFT57 PF10498.9 KFX92986.1 - 0.0015 17.6 7.3 0.0015 17.6 7.3 2.0 2 0 0 2 2 2 1 Intra-flagellar transport protein 57 Occludin_ELL PF07303.13 KFX92986.1 - 0.012 16.3 5.7 1.8 9.3 0.9 2.9 2 1 0 2 2 2 0 Occludin homology domain MIP-T3_C PF17749.1 KFX92986.1 - 0.028 14.4 3.8 0.028 14.4 3.8 2.9 2 1 0 2 2 2 0 Microtubule-binding protein MIP-T3 C-terminal region DUF948 PF06103.11 KFX92986.1 - 0.041 14.1 1.0 0.21 11.9 0.2 2.5 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) AAA_13 PF13166.6 KFX92986.1 - 0.14 10.7 15.8 0.59 8.7 10.4 2.5 1 1 0 2 2 2 0 AAA domain Laminin_II PF06009.12 KFX92986.1 - 0.21 11.6 9.6 0.043 13.8 1.9 2.5 2 1 1 3 3 3 0 Laminin Domain II LMBR1 PF04791.16 KFX92986.1 - 0.3 10.0 1.8 0.35 9.7 1.8 1.3 1 0 0 1 1 1 0 LMBR1-like membrane protein Spc7 PF08317.11 KFX92986.1 - 0.42 9.4 15.3 0.16 10.8 8.7 2.2 1 1 1 2 2 2 0 Spc7 kinetochore protein DUF3450 PF11932.8 KFX92986.1 - 1.3 8.3 9.0 0.54 9.5 1.1 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF3450) COG2 PF06148.11 KFX92986.1 - 1.5 8.9 7.6 0.24 11.5 1.2 2.6 2 1 1 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 FlaC_arch PF05377.11 KFX92986.1 - 1.9 8.9 9.2 0.57 10.6 2.0 3.3 3 1 0 3 3 3 0 Flagella accessory protein C (FlaC) DUF4407 PF14362.6 KFX92986.1 - 2.8 7.2 10.8 0.38 10.1 5.5 2.0 2 1 0 2 2 2 0 Domain of unknown function (DUF4407) ABC_tran_CTD PF16326.5 KFX92986.1 - 3.1 8.1 12.7 0.14 12.4 0.6 3.6 3 1 1 4 4 4 0 ABC transporter C-terminal domain DUF4140 PF13600.6 KFX92986.1 - 5.2 7.6 9.1 0.41 11.1 1.4 3.0 2 1 1 3 3 3 0 N-terminal domain of unknown function (DUF4140) Ax_dynein_light PF10211.9 KFX92986.1 - 5.6 6.9 14.6 0.18 11.7 2.8 2.9 2 1 1 4 4 3 0 Axonemal dynein light chain ECH_1 PF00378.20 KFX92988.1 - 5.2e-42 143.9 0.0 6.7e-42 143.5 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KFX92988.1 - 3.4e-23 82.7 0.0 4.5e-23 82.3 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase Beta-lactamase PF00144.24 KFX92989.1 - 1.4e-26 93.5 0.1 2.5e-26 92.7 0.1 1.3 1 0 0 1 1 1 1 Beta-lactamase Arginase PF00491.21 KFX92990.1 - 1.9e-85 286.8 0.3 2.4e-85 286.5 0.3 1.0 1 0 0 1 1 1 1 Arginase family SH3_9 PF14604.6 KFX92994.1 - 1.3e-12 47.4 0.1 2.7e-12 46.3 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KFX92994.1 - 5.3e-11 42.0 0.0 1.1e-10 40.9 0.0 1.6 1 0 0 1 1 1 1 SH3 domain PH PF00169.29 KFX92994.1 - 1.2e-08 35.4 0.0 7.4e-08 32.9 0.0 2.1 1 1 0 1 1 1 1 PH domain SAM_2 PF07647.17 KFX92994.1 - 1.3e-08 34.8 0.0 2.4e-08 34.0 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SH3_2 PF07653.17 KFX92994.1 - 2.9e-05 23.6 0.0 6.6e-05 22.5 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SAM_1 PF00536.30 KFX92994.1 - 0.0051 17.2 0.0 0.0088 16.5 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) PH_11 PF15413.6 KFX92994.1 - 0.0081 16.6 0.1 0.023 15.1 0.1 1.8 1 0 0 1 1 1 1 Pleckstrin homology domain PH_8 PF15409.6 KFX92994.1 - 0.1 12.9 0.0 0.44 10.8 0.0 2.1 2 0 0 2 2 2 0 Pleckstrin homology domain CCDC14 PF15254.6 KFX92994.1 - 0.52 8.9 7.0 0.81 8.3 7.0 1.2 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 14 FAD_binding_8 PF08022.12 KFX92995.1 - 1.1e-13 51.2 0.0 2.8e-13 49.9 0.0 1.6 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.12 KFX92995.1 - 1e-06 29.0 2.7 3.5e-06 27.2 2.7 1.9 1 1 0 1 1 1 1 Ferric reductase NAD binding domain NSP10 PF09401.10 KFX92995.1 - 0.13 12.3 3.3 0.27 11.3 1.2 2.2 2 0 0 2 2 2 0 RNA synthesis protein NSP10 Pkinase PF00069.25 KFX92999.1 - 8.3e-06 25.4 0.0 1.4e-05 24.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFX92999.1 - 4.7e-05 22.8 0.0 0.00011 21.6 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.23 KFX92999.1 - 0.053 13.4 0.1 0.14 12.1 0.1 1.7 1 0 0 1 1 1 0 Phosphotransferase enzyme family Zn_clus PF00172.18 KFX93000.1 - 6.2 7.0 12.1 12 6.1 12.1 1.5 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain WD40 PF00400.32 KFX93002.1 - 0.0088 16.9 3.1 0.087 13.7 0.7 3.5 3 0 0 3 3 3 1 WD domain, G-beta repeat BicD PF09730.9 KFX93002.1 - 0.039 12.4 13.0 0.055 11.9 13.0 1.1 1 0 0 1 1 1 0 Microtubule-associated protein Bicaudal-D FUSC PF04632.12 KFX93002.1 - 0.14 10.7 4.1 0.26 9.8 4.1 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family SKA1 PF07160.12 KFX93002.1 - 0.16 11.8 10.8 0.27 11.0 10.8 1.3 1 0 0 1 1 1 0 Spindle and kinetochore-associated protein 1 Alpha-E PF04168.12 KFX93002.1 - 0.64 9.7 3.8 1.1 8.9 3.8 1.3 1 0 0 1 1 1 0 A predicted alpha-helical domain with a conserved ER motif. V_ATPase_I PF01496.19 KFX93002.1 - 0.88 7.4 6.2 1.2 6.9 6.2 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Roughex PF06020.11 KFX93002.1 - 5.3 6.0 7.5 10 5.1 7.5 1.4 1 0 0 1 1 1 0 Drosophila roughex protein Baculo_p24 PF05073.12 KFX93002.1 - 6.6 6.5 7.6 13 5.5 7.6 1.4 1 0 0 1 1 1 0 Baculovirus P24 capsid protein ERAP1_C PF11838.8 KFX93003.1 - 3.4e-86 289.7 0.1 1.8e-85 287.3 0.0 2.0 2 0 0 2 2 2 1 ERAP1-like C-terminal domain Peptidase_M1 PF01433.20 KFX93003.1 - 3.1e-85 285.2 0.5 6e-85 284.2 0.5 1.5 1 0 0 1 1 1 1 Peptidase family M1 domain Peptidase_M1_N PF17900.1 KFX93003.1 - 6.7e-50 169.9 2.3 1.2e-49 169.1 2.3 1.4 1 0 0 1 1 1 1 Peptidase M1 N-terminal domain DUF3224 PF11528.8 KFX93003.1 - 0.062 13.1 0.2 0.11 12.3 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3224) DUF2808 PF10989.8 KFX93003.1 - 0.12 12.3 0.0 0.24 11.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2808) MFS_1 PF07690.16 KFX93004.1 - 2.3e-33 115.6 26.5 2.3e-33 115.6 26.5 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KFX93004.1 - 3e-05 23.1 13.5 3e-05 23.1 13.5 4.0 2 2 1 3 3 3 1 Sugar (and other) transporter CFEM PF05730.11 KFX93005.1 - 1.9e-11 43.9 13.8 3e-11 43.3 13.8 1.3 1 0 0 1 1 1 1 CFEM domain CP2 PF04516.15 KFX93006.1 - 1.7e-80 269.7 0.0 2.6e-80 269.0 0.0 1.3 1 0 0 1 1 1 1 CP2 transcription factor Tektin PF03148.14 KFX93006.1 - 0.024 13.4 0.0 0.039 12.7 0.0 1.2 1 0 0 1 1 1 0 Tektin family LPP PF04728.13 KFX93006.1 - 0.18 12.2 0.2 0.44 11.0 0.2 1.6 1 0 0 1 1 1 0 Lipoprotein leucine-zipper TMF_DNA_bd PF12329.8 KFX93006.1 - 0.25 11.4 0.7 0.5 10.4 0.7 1.4 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding Raptor_N PF14538.6 KFX93007.1 - 7e-65 217.5 0.0 1.5e-64 216.4 0.0 1.6 1 0 0 1 1 1 1 Raptor N-terminal CASPase like domain WD40 PF00400.32 KFX93007.1 - 7.9e-07 29.7 6.0 1.2 10.1 0.0 6.1 6 0 0 6 6 6 3 WD domain, G-beta repeat BBS2_Mid PF14783.6 KFX93007.1 - 0.0001 22.3 0.0 0.4 10.8 0.0 2.8 1 1 1 2 2 2 2 Ciliary BBSome complex subunit 2, middle region Atx10homo_assoc PF09759.9 KFX93007.1 - 0.00011 22.1 0.9 0.0003 20.8 0.9 1.7 1 0 0 1 1 1 1 Spinocerebellar ataxia type 10 protein domain SHE3 PF17078.5 KFX93007.1 - 0.0012 18.6 1.4 0.0012 18.6 1.4 1.6 2 0 0 2 2 2 1 SWI5-dependent HO expression protein 3 HEAT_2 PF13646.6 KFX93007.1 - 0.0045 17.4 0.1 1.5 9.2 0.0 3.9 4 0 0 4 4 4 1 HEAT repeats bZIP_1 PF00170.21 KFX93007.1 - 0.0048 17.0 6.0 0.011 15.8 6.0 1.7 1 0 0 1 1 1 1 bZIP transcription factor Cnd1 PF12717.7 KFX93007.1 - 0.0076 16.3 0.6 0.2 11.7 0.1 2.8 2 1 1 3 3 3 1 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 KFX93007.1 - 2.6 8.5 8.3 6 7.4 0.3 4.8 6 0 0 6 6 6 0 HEAT repeat ADH_zinc_N PF00107.26 KFX93009.1 - 4.5e-28 97.8 0.1 7.5e-28 97.1 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KFX93009.1 - 4.7e-18 66.5 0.0 1e-17 65.4 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KFX93009.1 - 0.00035 20.4 0.0 0.00077 19.3 0.0 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ELFV_dehydrog PF00208.21 KFX93009.1 - 0.028 14.1 0.4 0.044 13.5 0.4 1.3 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase SIS_2 PF13580.6 KFX93009.1 - 0.049 13.7 0.1 0.097 12.7 0.1 1.4 1 0 0 1 1 1 0 SIS domain 2-Hacid_dh_C PF02826.19 KFX93009.1 - 0.062 12.7 0.1 0.099 12.0 0.1 1.2 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ATP-sulfurylase PF01747.17 KFX93010.1 - 6.1e-88 293.8 0.0 8.6e-88 293.3 0.0 1.2 1 0 0 1 1 1 1 ATP-sulfurylase APS_kinase PF01583.20 KFX93010.1 - 5e-56 189.0 0.1 8.3e-56 188.3 0.1 1.3 1 0 0 1 1 1 1 Adenylylsulphate kinase PUA_2 PF14306.6 KFX93010.1 - 8.6e-52 175.0 0.0 1.4e-51 174.3 0.0 1.4 1 0 0 1 1 1 1 PUA-like domain Complex1_LYR PF05347.15 KFX93011.1 - 6e-20 71.0 4.5 8.4e-20 70.6 4.5 1.2 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 KFX93011.1 - 2.6e-05 24.9 2.0 2.9e-05 24.7 2.0 1.1 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR_1 PF13232.6 KFX93011.1 - 0.021 15.4 0.4 0.024 15.2 0.4 1.2 1 0 0 1 1 1 0 Complex1_LYR-like Glutaredoxin2_C PF04399.13 KFX93011.1 - 0.086 12.7 0.4 0.11 12.3 0.4 1.2 1 0 0 1 1 1 0 Glutaredoxin 2, C terminal domain Pkinase_Tyr PF07714.17 KFX93020.1 - 3.7e-18 65.8 0.0 3.2e-17 62.7 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KFX93020.1 - 1e-17 64.4 0.0 1.2e-17 64.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 KFX93020.1 - 0.003 17.5 1.3 0.0053 16.7 1.1 1.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KFX93020.1 - 0.04 13.5 0.0 0.063 12.9 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase Pyr_redox_2 PF07992.14 KFX93021.1 - 1.7e-38 132.6 0.0 5.6e-35 121.0 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KFX93021.1 - 1.2e-07 32.2 0.0 1.2e-05 25.7 0.0 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DUF3446 PF11928.8 KFX93021.1 - 0.16 12.3 12.6 1.5 9.2 4.3 3.1 3 0 0 3 3 3 0 Early growth response N-terminal domain NAPRTase PF04095.16 KFX93022.1 - 5.7e-51 173.4 0.0 7.4e-26 91.2 0.0 2.1 2 0 0 2 2 2 2 Nicotinate phosphoribosyltransferase (NAPRTase) family NAPRTase_N PF17767.1 KFX93022.1 - 3.1e-34 118.0 0.1 5.6e-34 117.2 0.1 1.5 1 0 0 1 1 1 1 Nicotinate phosphoribosyltransferase (NAPRTase) N-terminal domain DUF3464 PF11947.8 KFX93022.1 - 0.091 12.5 0.0 0.19 11.4 0.0 1.5 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 MFS_1 PF07690.16 KFX93023.1 - 8.6e-20 71.0 82.5 2.7e-14 52.9 43.2 3.2 1 1 2 3 3 3 3 Major Facilitator Superfamily Glyco_hydro_76 PF03663.14 KFX93024.1 - 8e-24 84.8 12.3 2.4e-16 60.2 1.5 2.2 2 0 0 2 2 2 2 Glycosyl hydrolase family 76 bZIP_1 PF00170.21 KFX93025.1 - 4.9e-07 29.8 6.5 4.9e-07 29.8 6.5 1.6 2 0 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.15 KFX93025.1 - 0.015 15.4 6.8 0.024 14.7 6.8 1.3 1 0 0 1 1 1 0 Basic region leucine zipper bZIP_Maf PF03131.17 KFX93025.1 - 4.5 7.9 9.7 2 9.0 7.4 1.6 1 1 0 1 1 1 0 bZIP Maf transcription factor rRNA_processing PF08524.11 KFX93026.1 - 0.043 13.9 1.4 0.064 13.3 1.4 1.2 1 0 0 1 1 1 0 rRNA processing Mago-bind PF09282.10 KFX93026.1 - 1.1 9.1 8.1 0.3 11.0 2.4 2.6 2 1 0 2 2 2 0 Mago binding E1-E2_ATPase PF00122.20 KFX93027.1 - 2e-11 43.8 1.6 4.7e-11 42.5 0.1 2.0 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_N PF00690.26 KFX93027.1 - 6.5e-10 38.6 0.0 1.3e-09 37.6 0.0 1.5 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus DUF2207 PF09972.9 KFX93027.1 - 0.0077 15.0 0.0 0.0094 14.8 0.0 1.2 1 0 0 1 1 1 1 Predicted membrane protein (DUF2207) MtrE PF04206.12 KFX93027.1 - 0.1 11.9 1.0 0.16 11.3 1.0 1.2 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, subunit E zf-RING_2 PF13639.6 KFX93028.1 - 1.6e-13 50.8 6.6 2.4e-13 50.2 6.6 1.3 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 KFX93028.1 - 9.7e-11 41.2 4.5 1.7e-10 40.4 4.5 1.4 1 0 0 1 1 1 1 RING-like zinc finger zf-RING_5 PF14634.6 KFX93028.1 - 2.4e-09 37.0 4.6 3.9e-09 36.3 4.6 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 KFX93028.1 - 1.5e-08 34.3 5.5 2.5e-08 33.6 5.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 KFX93028.1 - 2.2e-07 31.1 7.1 8.2e-07 29.2 7.1 1.9 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 KFX93028.1 - 3.2e-07 30.1 6.5 5.4e-07 29.4 6.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KFX93028.1 - 3.6e-07 29.9 5.3 6.4e-07 29.1 5.3 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_3 PF13920.6 KFX93028.1 - 4.1e-07 29.8 3.4 6.1e-07 29.2 3.4 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KFX93028.1 - 1.9e-06 27.8 4.4 2.2e-06 27.6 2.6 1.9 1 1 1 2 2 2 1 RING-type zinc-finger zf-ANAPC11 PF12861.7 KFX93028.1 - 9.4e-05 22.4 1.2 0.0002 21.4 1.2 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Zn_ribbon_17 PF17120.5 KFX93028.1 - 0.0028 17.2 2.0 0.0052 16.4 2.0 1.4 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-RING_4 PF14570.6 KFX93028.1 - 0.0071 16.1 3.8 0.012 15.4 3.8 1.4 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain FANCL_C PF11793.8 KFX93028.1 - 0.013 15.7 5.7 0.3 11.3 5.7 2.4 1 1 0 1 1 1 0 FANCL C-terminal domain zf-C3H2C3 PF17122.5 KFX93028.1 - 0.014 15.4 2.6 0.044 13.8 2.6 1.8 1 1 0 1 1 1 0 Zinc-finger Vps39_2 PF10367.9 KFX93028.1 - 0.015 15.7 3.4 2.1 8.8 2.9 2.8 2 1 0 2 2 2 0 Vacuolar sorting protein 39 domain 2 C1_1 PF00130.22 KFX93028.1 - 0.017 15.0 2.0 0.19 11.7 0.4 2.3 1 1 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) RINGv PF12906.7 KFX93028.1 - 0.032 14.4 2.8 0.08 13.1 2.8 1.7 1 1 0 1 1 1 0 RING-variant domain PHD PF00628.29 KFX93028.1 - 0.041 13.8 2.9 0.076 12.9 2.9 1.5 1 0 0 1 1 1 0 PHD-finger U-box PF04564.15 KFX93028.1 - 0.089 13.0 0.0 0.32 11.2 0.0 1.9 2 0 0 2 2 2 0 U-box domain zf-C3HC4_4 PF15227.6 KFX93028.1 - 0.19 11.9 5.3 0.74 10.0 5.3 2.0 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-P11 PF03854.14 KFX93028.1 - 0.24 11.1 6.8 0.59 9.8 6.8 1.7 1 1 0 1 1 1 0 P-11 zinc finger Zf_RING PF16744.5 KFX93028.1 - 0.3 11.2 1.5 0.66 10.1 1.5 1.6 1 0 0 1 1 1 0 KIAA1045 RING finger GAGA PF09237.11 KFX93028.1 - 0.31 10.9 2.6 1.4 8.8 0.4 2.4 2 0 0 2 2 2 0 GAGA factor Prok-RING_1 PF14446.6 KFX93028.1 - 0.49 10.4 4.1 5.6 7.0 1.1 2.3 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 K_trans PF02705.16 KFX93029.1 - 4.7e-182 606.2 27.0 5.5e-182 606.0 27.0 1.0 1 0 0 1 1 1 1 K+ potassium transporter DUF4291 PF14124.6 KFX93030.1 - 5e-68 228.5 0.3 6.5e-68 228.2 0.3 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4291) Pro_isomerase PF00160.21 KFX93031.1 - 3.9e-41 141.0 0.0 8e-41 139.9 0.0 1.5 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Ndc1_Nup PF09531.10 KFX93031.1 - 1.8 7.1 7.1 2.7 6.6 7.1 1.4 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup XAP5 PF04921.14 KFX93031.1 - 9.3 6.0 9.4 0.19 11.5 1.8 1.9 2 0 0 2 2 2 0 XAP5, circadian clock regulator TFIIA_gamma_C PF02751.14 KFX93032.1 - 1.2e-10 41.3 0.3 2.3e-10 40.4 0.3 1.4 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit TFIIA_gamma_N PF02268.16 KFX93032.1 - 1.5e-06 28.1 0.0 2.4e-06 27.5 0.0 1.4 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit, helical domain Ly-6_related PF06579.12 KFX93032.1 - 0.053 13.8 0.1 0.071 13.4 0.1 1.2 1 0 0 1 1 1 0 Caenorhabditis elegans ly-6-related protein APH PF01636.23 KFX93034.1 - 1.6e-06 28.2 0.0 6.4e-06 26.3 0.0 1.8 1 1 1 2 2 2 1 Phosphotransferase enzyme family Fructosamin_kin PF03881.14 KFX93034.1 - 0.022 14.0 0.0 0.036 13.3 0.0 1.3 1 0 0 1 1 1 0 Fructosamine kinase Spc29 PF17082.5 KFX93034.1 - 0.029 14.2 0.3 0.08 12.8 0.1 1.7 2 0 0 2 2 2 0 Spindle Pole Component 29 Troponin PF00992.20 KFX93034.1 - 0.16 12.3 0.7 0.29 11.4 0.2 1.6 2 0 0 2 2 2 0 Troponin 4HBT PF03061.22 KFX93047.1 - 6.5e-08 32.8 0.0 9.6e-08 32.3 0.0 1.3 1 0 0 1 1 1 1 Thioesterase superfamily 4HBT_2 PF13279.6 KFX93047.1 - 1.5e-06 28.7 0.0 1.8e-06 28.4 0.0 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily Acyl-ACP_TE PF01643.17 KFX93047.1 - 0.00014 21.2 0.2 0.00021 20.7 0.2 1.2 1 0 0 1 1 1 1 Acyl-ACP thioesterase SNF2_N PF00176.23 KFX93048.1 - 1e-22 80.3 0.0 2.6e-16 59.3 0.0 2.3 2 0 0 2 2 2 2 SNF2 family N-terminal domain DNA_methylase PF00145.17 KFX93048.1 - 4.5e-16 59.1 0.0 1.3e-15 57.6 0.0 1.9 1 1 0 1 1 1 1 C-5 cytosine-specific DNA methylase Helicase_C PF00271.31 KFX93048.1 - 3.6e-06 27.3 0.0 1.2e-05 25.7 0.0 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-RING_5 PF14634.6 KFX93048.1 - 0.005 16.8 6.9 0.005 16.8 6.9 2.6 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 KFX93048.1 - 1.5 8.9 8.8 1.9 8.6 1.3 2.6 2 0 0 2 2 2 0 RING-type zinc-finger Pyr_redox_2 PF07992.14 KFX93049.1 - 9.2e-17 61.2 0.0 2.3e-15 56.6 0.0 2.2 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KFX93049.1 - 5.2e-05 22.1 0.0 0.012 14.3 0.0 2.2 2 0 0 2 2 2 2 HI0933-like protein Pyr_redox_3 PF13738.6 KFX93049.1 - 0.00017 20.9 0.0 0.29 10.4 0.0 2.7 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 KFX93049.1 - 0.00024 20.3 0.6 0.48 9.5 0.0 2.3 1 1 1 2 2 2 2 Glucose inhibited division protein A NAD_binding_9 PF13454.6 KFX93049.1 - 0.0042 17.1 0.4 0.39 10.7 0.0 2.5 2 0 0 2 2 2 1 FAD-NAD(P)-binding FAD_binding_2 PF00890.24 KFX93049.1 - 0.031 13.3 0.0 0.085 11.9 0.0 1.7 2 0 0 2 2 2 0 FAD binding domain DAO PF01266.24 KFX93049.1 - 0.074 12.6 1.5 5.2 6.5 1.2 2.2 1 1 1 2 2 2 0 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 KFX93049.1 - 0.12 11.4 0.0 0.61 9.1 0.1 1.9 2 0 0 2 2 2 0 Lycopene cyclase protein TPR_12 PF13424.6 KFX93053.1 - 7.5e-51 170.3 16.2 1.8e-14 53.7 2.8 7.6 4 1 3 7 7 7 7 Tetratricopeptide repeat TPR_10 PF13374.6 KFX93053.1 - 4e-40 134.6 26.2 6.7e-06 25.8 0.2 10.1 10 0 0 10 10 10 7 Tetratricopeptide repeat NB-ARC PF00931.22 KFX93053.1 - 1.2e-17 64.0 0.0 2.2e-17 63.1 0.0 1.4 1 0 0 1 1 1 1 NB-ARC domain TPR_14 PF13428.6 KFX93053.1 - 1e-16 60.2 21.9 0.007 17.1 0.1 10.0 6 3 5 11 11 10 5 Tetratricopeptide repeat TPR_19 PF14559.6 KFX93053.1 - 2.9e-16 59.7 11.3 4e-05 24.0 1.0 7.2 4 2 3 7 7 7 5 Tetratricopeptide repeat TPR_2 PF07719.17 KFX93053.1 - 3e-12 45.6 27.1 0.0067 16.5 1.2 9.4 10 0 0 10 10 9 3 Tetratricopeptide repeat TPR_16 PF13432.6 KFX93053.1 - 1.8e-11 44.5 18.3 0.0015 19.1 2.9 8.4 5 3 3 8 8 8 2 Tetratricopeptide repeat SesA PF17107.5 KFX93053.1 - 3.4e-10 40.2 0.2 1.5e-09 38.1 0.1 2.2 2 0 0 2 2 1 1 N-terminal domain on NACHT_NTPase and P-loop NTPases TPR_8 PF13181.6 KFX93053.1 - 1.6e-09 37.2 18.6 0.013 15.7 0.2 9.3 11 0 0 11 11 9 1 Tetratricopeptide repeat TPR_MalT PF17874.1 KFX93053.1 - 4.8e-09 36.1 6.7 0.00041 19.8 0.6 3.9 1 1 2 3 3 3 3 MalT-like TPR region TPR_4 PF07721.14 KFX93053.1 - 1.3e-08 34.7 10.3 0.44 11.3 0.1 7.4 8 0 0 8 8 6 2 Tetratricopeptide repeat TPR_7 PF13176.6 KFX93053.1 - 3.9e-07 29.7 14.5 1.9 8.7 0.2 8.6 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_1 PF00515.28 KFX93053.1 - 6.1e-06 25.8 19.6 0.079 12.8 0.7 7.9 9 0 0 9 9 8 2 Tetratricopeptide repeat ANAPC3 PF12895.7 KFX93053.1 - 2.1e-05 24.7 5.5 0.037 14.2 0.7 5.4 3 1 3 6 6 6 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_20 PF14561.6 KFX93053.1 - 0.00011 22.5 6.1 0.27 11.6 0.8 6.0 7 0 0 7 7 7 1 Tetratricopeptide repeat AAA_16 PF13191.6 KFX93053.1 - 0.0003 21.2 0.2 0.0015 18.9 0.2 2.3 1 1 0 1 1 1 1 AAA ATPase domain TPR_17 PF13431.6 KFX93053.1 - 0.00054 20.1 0.8 0.067 13.6 0.3 3.8 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_5 PF12688.7 KFX93053.1 - 0.00062 20.0 3.8 1.6 9.0 0.2 4.0 2 1 2 4 4 3 2 Tetratrico peptide repeat TPR_11 PF13414.6 KFX93053.1 - 0.0022 17.6 2.9 12 5.7 0.0 4.0 3 0 0 3 3 3 0 TPR repeat NACHT PF05729.12 KFX93053.1 - 0.0046 16.9 0.0 0.011 15.7 0.0 1.7 1 0 0 1 1 1 1 NACHT domain TPR_6 PF13174.6 KFX93053.1 - 0.0062 17.1 17.0 2.7 8.8 0.4 7.1 7 0 0 7 7 6 2 Tetratricopeptide repeat AAA_22 PF13401.6 KFX93053.1 - 0.019 15.2 0.0 0.092 13.0 0.0 2.2 2 0 0 2 2 1 0 AAA domain RPN7 PF10602.9 KFX93053.1 - 0.043 13.5 4.5 15 5.2 0.1 4.3 1 1 1 4 4 4 0 26S proteasome subunit RPN7 Zeta_toxin PF06414.12 KFX93053.1 - 0.057 12.7 0.0 0.11 11.7 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin TniB PF05621.11 KFX93053.1 - 0.099 12.0 0.0 0.27 10.6 0.0 1.7 1 0 0 1 1 1 0 Bacterial TniB protein DUF87 PF01935.17 KFX93053.1 - 0.29 11.2 1.5 15 5.6 0.2 2.7 2 1 0 2 2 2 0 Helicase HerA, central domain ADH_N PF08240.12 KFX93054.1 - 1.1e-09 38.1 0.1 2e-09 37.3 0.1 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KFX93054.1 - 5.4e-08 32.9 0.0 9.6e-08 32.1 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KFX93054.1 - 0.00012 23.1 0.0 0.0002 22.4 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Fungal_trans PF04082.18 KFX93055.1 - 6.7e-31 107.3 0.4 1.5e-30 106.2 0.4 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KFX93055.1 - 1.1e-07 31.9 15.8 2.7e-07 30.6 15.8 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Choline_kinase PF01633.20 KFX93061.1 - 0.028 14.0 0.0 0.1 12.2 0.0 2.0 2 0 0 2 2 2 0 Choline/ethanolamine kinase CAML PF14963.6 KFX93061.1 - 0.11 12.6 3.2 0.21 11.7 3.2 1.3 1 0 0 1 1 1 0 Calcium signal-modulating cyclophilin ligand TauD PF02668.16 KFX93063.1 - 1.3e-48 166.1 0.0 2e-48 165.5 0.0 1.3 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Fn3-like PF14310.6 KFX93063.1 - 0.11 12.6 0.2 0.47 10.6 0.0 2.1 2 0 0 2 2 2 0 Fibronectin type III-like domain MFS_1 PF07690.16 KFX93064.1 - 2e-23 82.9 20.9 2.9e-23 82.4 20.9 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Fungal_trans PF04082.18 KFX93064.1 - 3.8e-10 39.3 0.1 7.7e-10 38.2 0.1 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF2104 PF09877.9 KFX93064.1 - 0.017 15.4 0.3 0.088 13.1 0.2 2.3 2 0 0 2 2 2 0 Predicted membrane protein (DUF2104) DUF3712 PF12505.8 KFX93065.1 - 2.5e-37 127.9 4.1 5.1e-37 126.9 0.8 2.4 3 0 0 3 3 3 1 Protein of unknown function (DUF3712) DUF2236 PF09995.9 KFX93066.1 - 4.4e-56 190.6 2.2 5.6e-56 190.3 2.2 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2236) Fungal_trans PF04082.18 KFX93068.1 - 0.023 13.7 3.4 0.056 12.5 3.3 1.6 1 1 0 1 1 1 0 Fungal specific transcription factor domain AMP-binding PF00501.28 KFX93069.1 - 6.7e-77 258.9 0.0 8.5e-77 258.5 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KFX93069.1 - 7e-16 59.0 0.5 1.7e-15 57.8 0.5 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Acyl-CoA_dh_1 PF00441.24 KFX93070.1 - 9.1e-33 113.6 0.3 1.5e-32 112.9 0.3 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 KFX93070.1 - 2.8e-23 81.9 0.4 5.7e-23 80.9 0.1 1.7 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 KFX93070.1 - 4.8e-18 65.9 0.0 1.8e-17 64.0 0.0 2.1 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 KFX93070.1 - 3.2e-05 24.2 0.1 5.2e-05 23.5 0.1 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain FMO-like PF00743.19 KFX93071.1 - 1.3e-28 99.8 0.0 1.5e-11 43.5 0.0 3.0 3 0 0 3 3 3 3 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 KFX93071.1 - 2e-14 53.6 0.0 4.7e-11 42.5 0.1 2.8 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KFX93071.1 - 2.8e-12 46.5 0.0 1.4e-11 44.2 0.0 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KFX93071.1 - 3e-06 27.3 0.4 0.012 15.6 0.0 3.6 4 0 0 4 4 4 1 FAD-NAD(P)-binding K_oxygenase PF13434.6 KFX93071.1 - 3.4e-06 26.4 2.4 0.0027 16.9 0.1 3.7 2 1 2 4 4 4 2 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 KFX93071.1 - 6.3e-05 23.1 0.3 0.0003 21.0 0.0 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KFX93071.1 - 9.2e-05 22.2 0.3 0.5 9.9 0.0 3.8 4 0 0 4 4 4 2 FAD dependent oxidoreductase Thi4 PF01946.17 KFX93071.1 - 0.0074 15.6 1.1 0.37 10.0 0.1 2.3 2 0 0 2 2 2 1 Thi4 family Shikimate_DH PF01488.20 KFX93071.1 - 0.019 15.0 0.5 0.66 10.0 0.1 2.5 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Pyr_redox PF00070.27 KFX93071.1 - 0.04 14.5 0.8 9.5 6.9 0.1 2.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 KFX93071.1 - 0.071 12.3 0.3 0.14 11.4 0.0 1.6 2 0 0 2 2 2 0 FAD binding domain HI0933_like PF03486.14 KFX93071.1 - 1 8.0 4.2 0.28 9.8 0.7 1.8 2 0 0 2 2 2 0 HI0933-like protein MFS_1 PF07690.16 KFX93072.1 - 3.5e-32 111.7 24.6 6.7e-32 110.8 24.6 1.5 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF3488 PF11992.8 KFX93072.1 - 0.092 11.7 2.9 0.091 11.7 0.7 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3488) Inhibitor_I68 PF10468.9 KFX93073.1 - 0.24 11.8 0.5 0.24 11.8 0.5 1.8 2 1 0 2 2 2 0 Carboxypeptidase inhibitor I68 OHCU_decarbox PF09349.10 KFX93075.1 - 2.5e-49 167.7 0.0 2.9e-49 167.5 0.0 1.0 1 0 0 1 1 1 1 OHCU decarboxylase GPI-anchored PF10342.9 KFX93088.1 - 3.6e-12 46.9 0.0 5.2e-12 46.4 0.0 1.2 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Cyclin PF08613.11 KFX93089.1 - 9.1e-46 156.2 0.0 1.2e-45 155.8 0.0 1.1 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.23 KFX93089.1 - 0.056 13.2 0.0 0.083 12.6 0.0 1.3 1 0 0 1 1 1 0 Cyclin, N-terminal domain CLU_N PF15044.6 KFX93089.1 - 0.084 13.3 0.0 0.16 12.3 0.0 1.4 1 0 0 1 1 1 0 Mitochondrial function, CLU-N-term ATP11 PF06644.11 KFX93093.1 - 5.3e-99 331.4 0.0 6.1e-99 331.2 0.0 1.0 1 0 0 1 1 1 1 ATP11 protein MSA-2c PF12238.8 KFX93093.1 - 0.1 12.6 3.3 0.15 12.0 3.3 1.2 1 0 0 1 1 1 0 Merozoite surface antigen 2c Mito_fiss_reg PF05308.11 KFX93093.1 - 0.27 11.3 3.6 0.38 10.8 3.6 1.2 1 0 0 1 1 1 0 Mitochondrial fission regulator AMP-binding PF00501.28 KFX93094.1 - 6.5e-99 331.4 0.0 7.7e-99 331.1 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KFX93094.1 - 1.1e-13 51.9 0.2 2.3e-13 50.9 0.2 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Fungal_trans_2 PF11951.8 KFX93095.1 - 9.3e-57 192.6 0.7 1.3e-56 192.1 0.7 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KFX93095.1 - 4.1e-08 33.2 8.0 7.6e-08 32.4 8.0 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pro_isomerase PF00160.21 KFX93096.1 - 7.4e-51 172.6 0.1 1.4e-50 171.7 0.1 1.5 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD WD40 PF00400.32 KFX93096.1 - 2.9e-10 40.6 0.0 7.1e-05 23.5 0.0 4.9 5 0 0 5 5 5 2 WD domain, G-beta repeat Ge1_WD40 PF16529.5 KFX93096.1 - 0.0052 15.8 0.2 0.09 11.7 0.1 2.2 1 1 1 2 2 2 1 WD40 region of Ge1, enhancer of mRNA-decapping protein ANAPC4_WD40 PF12894.7 KFX93096.1 - 0.0064 16.8 0.0 0.044 14.1 0.0 2.4 3 0 0 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain Far-17a_AIG1 PF04750.14 KFX93097.1 - 9.1e-52 175.3 13.7 1.1e-51 175.1 13.7 1.0 1 0 0 1 1 1 1 FAR-17a/AIG1-like protein eIF2A PF08662.11 KFX93098.1 - 1.2e-34 119.9 2.9 3e-33 115.3 0.3 3.6 2 2 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A RRM_1 PF00076.22 KFX93098.1 - 1.2e-06 28.2 0.0 2.5e-06 27.2 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) WD40 PF00400.32 KFX93098.1 - 0.024 15.5 1.8 0.38 11.7 0.0 3.7 5 0 0 5 5 5 0 WD domain, G-beta repeat Cpn60_TCP1 PF00118.24 KFX93099.1 - 8.1e-141 470.0 12.6 9.3e-141 469.8 12.6 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family DUF1132 PF06575.12 KFX93099.1 - 0.087 13.2 0.0 0.27 11.6 0.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF1132) CRM1_repeat PF18777.1 KFX93099.1 - 0.098 12.2 0.0 0.2 11.2 0.0 1.5 1 0 0 1 1 1 0 Chromosome region maintenance or exportin repeat Response_reg PF00072.24 KFX93104.1 - 1.4e-16 60.6 0.0 1.8e-16 60.3 0.0 1.1 1 0 0 1 1 1 1 Response regulator receiver domain Velvet PF11754.8 KFX93107.1 - 6.8e-13 49.1 1.3 6.8e-13 49.1 1.3 2.1 2 0 0 2 2 2 1 Velvet factor UbiA PF01040.18 KFX93110.1 - 2.1e-43 148.5 21.9 3.2e-43 147.9 21.9 1.2 1 0 0 1 1 1 1 UbiA prenyltransferase family Tropomyosin_1 PF12718.7 KFX93117.1 - 0.0067 16.6 16.6 0.11 12.6 14.3 2.3 2 0 0 2 2 2 1 Tropomyosin like DUF4407 PF14362.6 KFX93117.1 - 0.0097 15.3 1.2 0.015 14.7 1.2 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4407) Tropomyosin PF00261.20 KFX93117.1 - 0.019 14.4 16.6 0.022 14.1 15.1 1.8 2 0 0 2 2 2 0 Tropomyosin DUF5082 PF16888.5 KFX93117.1 - 0.045 14.0 2.0 0.16 12.3 1.9 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF5082) GAS PF13851.6 KFX93117.1 - 0.36 10.2 7.4 0.94 8.8 7.4 1.7 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding Spc7 PF08317.11 KFX93117.1 - 0.75 8.6 9.4 1.2 7.9 9.4 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein Prefoldin_2 PF01920.20 KFX93117.1 - 0.89 9.5 8.5 5.5 7.0 1.2 3.2 2 1 1 3 3 3 0 Prefoldin subunit Macoilin PF09726.9 KFX93117.1 - 0.99 7.9 11.9 0.021 13.4 5.5 1.4 2 0 0 2 2 2 0 Macoilin family FUSC PF04632.12 KFX93117.1 - 3.2 6.2 5.1 5.5 5.4 5.1 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family TMF_DNA_bd PF12329.8 KFX93117.1 - 5.5 7.1 15.4 4.4 7.4 0.3 2.4 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding zf-U1 PF06220.12 KFX93120.1 - 1.5e-22 79.0 3.4 2.1e-22 78.6 3.4 1.2 1 0 0 1 1 1 1 U1 zinc finger Actin_micro PF17003.5 KFX93120.1 - 0.032 13.4 0.2 0.033 13.4 0.2 1.0 1 0 0 1 1 1 0 Putative actin-like family zf-C2H2_jaz PF12171.8 KFX93120.1 - 8.2 6.8 7.0 87 3.6 7.0 2.2 1 1 0 1 1 1 0 Zinc-finger double-stranded RNA-binding EMP24_GP25L PF01105.24 KFX93121.1 - 7.3e-50 169.4 0.7 4.1e-25 88.8 0.1 2.0 1 1 1 2 2 2 2 emp24/gp25L/p24 family/GOLD DUF4665 PF15679.5 KFX93121.1 - 6.2e-05 23.6 0.4 0.41 11.3 0.2 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF4665) EzrA PF06160.12 KFX93121.1 - 0.0036 15.5 6.1 0.07 11.3 1.9 2.0 1 1 1 2 2 2 2 Septation ring formation regulator, EzrA LOH1CR12 PF10158.9 KFX93121.1 - 0.021 14.9 1.2 5.9 6.9 0.1 2.2 1 1 1 2 2 2 0 Tumour suppressor protein MtrB PF05440.12 KFX93121.1 - 0.021 15.2 1.5 6.5 7.2 0.1 2.5 1 1 1 2 2 2 0 Tetrahydromethanopterin S-methyltransferase subunit B CLZ PF16526.5 KFX93121.1 - 0.026 14.8 3.2 0.12 12.7 1.1 2.2 2 0 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels FapA PF03961.13 KFX93121.1 - 0.031 12.9 0.3 0.044 12.4 0.3 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A Allexi_40kDa PF05549.11 KFX93121.1 - 0.044 13.3 0.3 0.062 12.8 0.3 1.2 1 0 0 1 1 1 0 Allexivirus 40kDa protein DUF2730 PF10805.8 KFX93121.1 - 0.048 13.8 1.6 0.1 12.7 1.6 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2730) OmdA PF13376.6 KFX93121.1 - 0.056 13.5 0.9 9.9 6.3 0.0 2.7 2 0 0 2 2 2 0 Bacteriocin-protection, YdeI or OmpD-Associated Spore_III_AB PF09548.10 KFX93121.1 - 0.059 13.5 0.1 2.4 8.2 0.0 2.2 2 0 0 2 2 2 0 Stage III sporulation protein AB (spore_III_AB) DegS PF05384.11 KFX93121.1 - 0.08 12.4 6.7 0.41 10.1 1.6 2.2 1 1 1 2 2 2 0 Sensor protein DegS MCU PF04678.13 KFX93121.1 - 0.099 12.7 0.6 0.17 11.9 0.6 1.5 1 1 0 1 1 1 0 Mitochondrial calcium uniporter Noelin-1 PF12308.8 KFX93121.1 - 0.11 12.5 2.4 4 7.5 0.9 2.3 1 1 1 2 2 2 0 Neurogenesis glycoprotein MCPsignal PF00015.21 KFX93121.1 - 0.16 11.8 0.9 0.89 9.3 0.8 2.0 1 1 1 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain STAT_alpha PF01017.20 KFX93121.1 - 0.17 11.8 2.2 0.27 11.1 2.2 1.2 1 0 0 1 1 1 0 STAT protein, all-alpha domain YojJ PF10372.9 KFX93121.1 - 0.3 11.2 1.3 26 5.0 0.1 2.3 2 0 0 2 2 2 0 Bacterial membrane-spanning protein N-terminus DHR10 PF18595.1 KFX93121.1 - 0.51 10.4 6.4 1.2 9.3 1.8 2.3 1 1 1 2 2 2 0 Designed helical repeat protein 10 domain DUF4806 PF16064.5 KFX93121.1 - 1.3 9.4 6.6 12 6.3 0.7 3.1 2 1 1 3 3 3 0 Domain of unknown function (DUF4806) Med21 PF11221.8 KFX93121.1 - 1.6 9.0 5.7 3.4 7.9 3.3 1.9 1 1 1 2 2 2 0 Subunit 21 of Mediator complex YabA PF06156.13 KFX93121.1 - 2 9.1 7.0 2.2 9.0 2.1 2.6 2 1 1 3 3 3 0 Initiation control protein YabA Alg14 PF08660.11 KFX93124.1 - 7.9e-36 123.6 0.0 1.1e-35 123.1 0.0 1.2 1 0 0 1 1 1 1 Oligosaccharide biosynthesis protein Alg14 like KOW PF00467.29 KFX93125.1 - 1.6e-05 24.7 0.3 3.3e-05 23.7 0.3 1.6 1 0 0 1 1 1 1 KOW motif VGCC_beta4Aa_N PF12052.8 KFX93125.1 - 3 8.0 7.4 3.2 7.9 0.3 3.0 2 0 0 2 2 2 0 Voltage gated calcium channel subunit beta domain 4Aa N terminal Ras PF00071.22 KFX93126.1 - 7.6e-56 188.2 0.0 8.8e-56 188.0 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFX93126.1 - 8e-22 77.7 0.0 1.2e-21 77.2 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFX93126.1 - 3.7e-07 29.8 0.0 5.9e-07 29.1 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 KFX93126.1 - 0.0017 17.8 0.0 0.0024 17.3 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit baeRF_family3 PF18845.1 KFX93126.1 - 0.034 14.4 0.0 0.14 12.4 0.0 1.8 1 1 1 2 2 2 0 Bacterial archaeo-eukaryotic release factor family 3 NB-ARC PF00931.22 KFX93126.1 - 0.069 12.3 0.1 0.82 8.8 0.0 2.0 1 1 0 2 2 2 0 NB-ARC domain Gtr1_RagA PF04670.12 KFX93126.1 - 0.15 11.4 0.0 0.2 11.0 0.0 1.4 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region Choline_transpo PF04515.12 KFX93128.1 - 3.6e-80 269.6 32.8 3.6e-80 269.6 32.8 2.1 2 0 0 2 2 2 1 Plasma-membrane choline transporter Pex14_N PF04695.13 KFX93128.1 - 0.027 15.2 8.0 0.06 14.0 8.0 1.5 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Spt20 PF12090.8 KFX93128.1 - 0.055 13.1 16.8 0.081 12.5 16.8 1.2 1 0 0 1 1 1 0 Spt20 family Deltameth_res PF16020.5 KFX93128.1 - 7.7 6.5 8.3 24 4.9 0.0 4.1 3 0 0 3 3 3 0 Deltamethrin resistance Cellulase PF00150.18 KFX93129.1 - 2e-45 155.4 0.0 2.8e-45 154.9 0.0 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) DUF1681 PF07933.14 KFX93133.1 - 4.4e-34 117.3 0.0 5.9e-34 116.9 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1681) Tom37 PF10568.9 KFX93135.1 - 4.3e-15 56.1 0.0 5.3e-15 55.8 0.0 1.1 1 0 0 1 1 1 1 Outer mitochondrial membrane transport complex protein MIP PF00230.20 KFX93140.1 - 2.2e-49 168.2 4.1 3e-49 167.8 4.1 1.1 1 0 0 1 1 1 1 Major intrinsic protein NUP PF06516.11 KFX93141.1 - 5.8e-127 423.2 0.0 6.9e-127 423.0 0.0 1.1 1 0 0 1 1 1 1 Purine nucleoside permease (NUP) Wzy_C PF04932.15 KFX93142.1 - 0.046 13.3 0.2 0.046 13.3 0.2 3.1 3 1 1 4 4 4 0 O-Antigen ligase p450 PF00067.22 KFX93143.1 - 2.1e-64 218.0 0.0 2.5e-64 217.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 CFEM PF05730.11 KFX93144.1 - 2.6e-13 49.9 10.6 4.4e-13 49.1 10.6 1.4 1 0 0 1 1 1 1 CFEM domain Abhydrolase_6 PF12697.7 KFX93145.1 - 0.00031 21.4 8.9 0.00037 21.2 8.9 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Say1_Mug180 PF10340.9 KFX93145.1 - 0.0069 15.3 0.0 0.01 14.8 0.0 1.1 1 0 0 1 1 1 1 Steryl acetyl hydrolase Abhydrolase_1 PF00561.20 KFX93145.1 - 0.0072 16.0 0.2 0.011 15.4 0.2 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold RNA_polI_A34 PF08208.11 KFX93146.1 - 1.8e-22 80.5 9.9 2e-22 80.3 9.9 1.0 1 0 0 1 1 1 1 DNA-directed RNA polymerase I subunit RPA34.5 RR_TM4-6 PF06459.12 KFX93146.1 - 0.68 9.7 7.4 0.77 9.5 7.4 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 MTS PF05175.14 KFX93149.1 - 0.0053 16.3 0.0 0.26 10.8 0.0 2.7 2 1 0 2 2 2 1 Methyltransferase small domain Methyltransf_25 PF13649.6 KFX93149.1 - 0.026 15.2 0.4 0.13 13.0 0.1 2.2 2 1 0 2 2 2 0 Methyltransferase domain Methyltransf_12 PF08242.12 KFX93149.1 - 0.046 14.5 0.0 0.072 13.8 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.12 KFX93149.1 - 0.16 12.7 0.3 9.9 6.9 0.2 2.7 2 1 0 2 2 2 0 Methyltransferase domain A_deaminase PF00962.22 KFX93163.1 - 2e-78 264.0 0.0 2.3e-78 263.8 0.0 1.0 1 0 0 1 1 1 1 Adenosine/AMP deaminase Amidohydro_1 PF01979.20 KFX93163.1 - 0.00075 18.9 0.0 0.0018 17.7 0.0 1.5 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 KFX93163.1 - 0.022 14.3 0.0 0.033 13.7 0.0 1.2 1 0 0 1 1 1 0 Amidohydrolase family MFS_1 PF07690.16 KFX93165.1 - 3e-17 62.6 28.3 4.8e-17 61.9 28.3 1.4 1 0 0 1 1 1 1 Major Facilitator Superfamily PUCC PF03209.15 KFX93165.1 - 0.0034 16.4 6.8 0.009 15.0 4.8 2.1 2 0 0 2 2 2 1 PUCC protein OATP PF03137.20 KFX93165.1 - 0.33 9.2 8.4 0.018 13.3 1.3 2.1 1 1 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family PAP_central PF04928.17 KFX93166.1 - 1.2e-110 368.3 0.0 1.7e-110 367.9 0.0 1.2 1 0 0 1 1 1 1 Poly(A) polymerase central domain PAP_RNA-bind PF04926.15 KFX93166.1 - 8.6e-63 211.0 0.4 4.8e-62 208.6 0.4 2.1 1 1 0 1 1 1 1 Poly(A) polymerase predicted RNA binding domain NTP_transf_2 PF01909.23 KFX93166.1 - 2e-09 37.6 0.0 2e-09 37.6 0.0 1.9 2 0 0 2 2 2 1 Nucleotidyltransferase domain Nrap_D2 PF17403.2 KFX93166.1 - 0.17 11.7 0.0 0.28 11.0 0.0 1.4 1 0 0 1 1 1 0 Nrap protein PAP/OAS-like domain DnaJ PF00226.31 KFX93167.1 - 7.7e-16 58.0 1.4 1.8e-15 56.8 1.4 1.7 1 0 0 1 1 1 1 DnaJ domain Sec63 PF02889.16 KFX93167.1 - 1.9e-10 40.3 0.0 1.6e-09 37.3 0.0 2.0 1 1 0 1 1 1 1 Sec63 Brl domain Ras PF00071.22 KFX93171.1 - 6.1e-13 48.7 0.1 6.4e-13 48.6 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFX93171.1 - 1.3e-06 28.6 0.0 1.3e-06 28.6 0.0 1.0 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFX93171.1 - 0.051 13.0 0.0 0.057 12.9 0.0 1.0 1 0 0 1 1 1 0 ADP-ribosylation factor family AAA_7 PF12775.7 KFX93171.1 - 0.075 12.5 0.0 0.075 12.5 0.0 1.0 1 0 0 1 1 1 0 P-loop containing dynein motor region DUF2577 PF10844.8 KFX93184.1 - 0.094 12.9 0.0 0.13 12.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2577) Zn_clus PF00172.18 KFX93185.1 - 0.054 13.6 8.1 0.35 11.0 8.2 2.0 1 1 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Pox_E10 PF04805.12 KFX93185.1 - 0.083 12.8 0.3 0.15 11.9 0.3 1.4 1 0 0 1 1 1 0 E10-like protein conserved region V-SNARE_C PF12352.8 KFX93185.1 - 0.14 12.4 1.9 0.25 11.7 1.9 1.5 1 1 0 1 1 1 0 Snare region anchored in the vesicle membrane C-terminus ThrE PF06738.12 KFX93186.1 - 2e-66 223.8 18.4 5.4e-63 212.6 0.8 2.4 3 0 0 3 3 3 2 Putative threonine/serine exporter ThrE_2 PF12821.7 KFX93186.1 - 6e-14 52.3 7.9 6e-14 52.3 7.9 2.7 3 0 0 3 3 3 1 Threonine/Serine exporter, ThrE RVT_connect PF06815.13 KFX93188.1 - 0.049 13.9 0.0 0.059 13.6 0.0 1.1 1 0 0 1 1 1 0 Reverse transcriptase connection domain DUF5097 PF17020.5 KFX93188.1 - 0.11 12.8 0.0 0.13 12.7 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF5097) Glyco_hydro_18 PF00704.28 KFX93190.1 - 3.6e-43 148.5 1.3 7e-43 147.5 1.3 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 LysM PF01476.20 KFX93190.1 - 1.6e-05 24.9 0.0 0.25 11.4 0.0 3.4 3 0 0 3 3 3 2 LysM domain Chitin_bind_1 PF00187.19 KFX93190.1 - 0.0002 21.8 7.9 0.0002 21.8 7.9 4.1 3 1 0 3 3 3 1 Chitin recognition protein RTA1 PF04479.13 KFX93191.1 - 6.3e-52 176.2 10.6 8.3e-52 175.8 10.6 1.2 1 0 0 1 1 1 1 RTA1 like protein LIAS_N PF16881.5 KFX93193.1 - 1.1e-14 54.7 0.0 2.4e-14 53.6 0.0 1.6 1 0 0 1 1 1 1 N-terminal domain of lipoyl synthase of Radical_SAM family Radical_SAM PF04055.21 KFX93193.1 - 6.8e-13 49.3 0.0 1.6e-12 48.1 0.0 1.6 1 1 0 1 1 1 1 Radical SAM superfamily SKG6 PF08693.10 KFX93198.1 - 1.2e-05 24.6 5.1 2.7e-05 23.5 5.1 1.6 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Phage_holin_2_4 PF16082.5 KFX93198.1 - 5e-05 23.0 0.4 0.00018 21.2 0.4 1.9 1 0 0 1 1 1 1 Bacteriophage holin family, superfamily II-like TMEM154 PF15102.6 KFX93198.1 - 0.0039 17.1 5.1 0.14 12.1 5.1 2.7 1 1 0 1 1 1 1 TMEM154 protein family CcmD PF04995.14 KFX93198.1 - 0.008 16.2 1.7 0.015 15.3 1.7 1.5 1 0 0 1 1 1 1 Heme exporter protein D (CcmD) DUF4381 PF14316.6 KFX93198.1 - 0.033 14.4 0.1 0.053 13.8 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) DUF4010 PF13194.6 KFX93198.1 - 0.048 13.3 0.6 0.084 12.5 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4010) DUF4448 PF14610.6 KFX93198.1 - 0.088 12.6 0.0 0.13 12.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) DUF3301 PF11743.8 KFX93198.1 - 0.09 12.5 0.2 0.18 11.5 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3301) Stevor PF17410.2 KFX93198.1 - 0.33 10.4 0.1 0.51 9.8 0.1 1.1 1 0 0 1 1 1 0 Subtelomeric Variable Open Reading frame Ndc1_Nup PF09531.10 KFX93198.1 - 8.4 4.9 6.6 12 4.5 6.6 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup tRNA_anti-codon PF01336.25 KFX93200.1 - 0.0001 22.2 0.0 0.00032 20.6 0.0 1.9 1 1 0 1 1 1 1 OB-fold nucleic acid binding domain Glyco_transf_7N PF13733.6 KFX93200.1 - 0.13 11.9 0.1 0.24 11.0 0.1 1.4 1 0 0 1 1 1 0 N-terminal region of glycosyl transferase group 7 ADH_N PF08240.12 KFX93201.1 - 5.8e-23 80.9 4.9 9.3e-23 80.2 4.9 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KFX93201.1 - 2e-15 56.9 0.0 5.6e-15 55.5 0.0 1.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 KFX93201.1 - 0.00019 20.8 0.0 0.00039 19.8 0.0 1.5 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.19 KFX93201.1 - 0.003 16.9 0.0 0.0053 16.1 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Gp_dh_N PF00044.24 KFX93201.1 - 0.028 14.8 0.0 1.4 9.4 0.0 2.4 2 0 0 2 2 2 0 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain Grg1 PF11034.8 KFX93202.1 - 7e-31 106.3 14.9 7.7e-31 106.1 14.9 1.0 1 0 0 1 1 1 1 Glucose-repressible protein Grg1 Phe_tRNA-synt_N PF02912.18 KFX93202.1 - 0.017 15.0 1.9 0.018 15.0 1.3 1.4 1 1 0 1 1 1 0 Aminoacyl tRNA synthetase class II, N-terminal domain Glyco_transf_20 PF00982.21 KFX93205.1 - 3.3e-147 491.0 0.0 5.8e-147 490.2 0.0 1.3 2 0 0 2 2 2 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.16 KFX93205.1 - 6.3e-74 248.0 0.0 1.4e-73 246.9 0.0 1.6 2 0 0 2 2 2 1 Trehalose-phosphatase Glyco_transf_5 PF08323.11 KFX93205.1 - 0.044 13.5 0.0 0.093 12.4 0.0 1.5 1 0 0 1 1 1 0 Starch synthase catalytic domain Glycos_transf_1 PF00534.20 KFX93205.1 - 0.084 12.4 0.0 0.41 10.2 0.0 2.1 1 1 0 1 1 1 0 Glycosyl transferases group 1 ABC_membrane PF00664.23 KFX93206.1 - 1.2e-41 143.2 11.3 1.2e-41 143.2 11.3 4.0 4 0 0 4 4 4 1 ABC transporter transmembrane region ABC_tran PF00005.27 KFX93206.1 - 1.3e-34 119.7 0.0 2.6e-34 118.7 0.0 1.6 1 0 0 1 1 1 1 ABC transporter MFS_1 PF07690.16 KFX93206.1 - 5.6e-30 104.5 45.0 5.6e-30 104.5 45.0 2.7 3 0 0 3 3 3 1 Major Facilitator Superfamily Metallophos PF00149.28 KFX93206.1 - 7.5e-10 39.6 1.8 4e-09 37.3 1.8 2.0 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase SMC_N PF02463.19 KFX93206.1 - 1.8e-05 24.3 0.0 0.0035 16.8 0.0 2.3 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 KFX93206.1 - 0.00016 22.1 0.0 0.00031 21.2 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain AAA PF00004.29 KFX93206.1 - 0.001 19.5 0.0 0.13 12.6 0.0 2.9 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_21 PF13304.6 KFX93206.1 - 0.0016 18.3 0.0 0.027 14.3 0.0 2.2 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 KFX93206.1 - 0.0021 18.3 0.1 0.0079 16.5 0.0 1.9 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.23 KFX93206.1 - 0.0046 17.0 0.0 0.18 11.9 0.0 2.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KFX93206.1 - 0.0062 16.5 0.0 0.012 15.5 0.0 1.5 1 0 0 1 1 1 1 RsgA GTPase Orf78 PF06024.12 KFX93206.1 - 0.015 15.6 0.2 0.038 14.3 0.2 1.7 1 0 0 1 1 1 0 Orf78 (ac78) AAA_14 PF13173.6 KFX93206.1 - 0.02 14.9 0.0 0.13 12.3 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 KFX93206.1 - 0.025 14.3 0.0 0.049 13.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 KFX93206.1 - 0.03 14.1 0.1 0.083 12.6 0.1 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain Rad17 PF03215.15 KFX93206.1 - 0.031 14.2 0.0 0.074 13.0 0.0 1.6 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_25 PF13481.6 KFX93206.1 - 0.053 13.1 0.0 0.17 11.5 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_15 PF13175.6 KFX93206.1 - 0.086 12.5 0.0 0.13 11.9 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain AAA_10 PF12846.7 KFX93206.1 - 0.089 11.7 0.0 0.17 10.8 0.0 1.3 1 0 0 1 1 1 0 AAA-like domain AAA_28 PF13521.6 KFX93206.1 - 0.1 12.8 0.0 0.24 11.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain GPAT_N PF14829.6 KFX93206.1 - 0.11 12.5 0.0 7 6.7 0.0 2.5 2 0 0 2 2 2 0 Glycerol-3-phosphate acyltransferase N-terminal AAA_7 PF12775.7 KFX93206.1 - 0.14 11.6 0.0 0.46 10.0 0.0 1.8 2 0 0 2 2 2 0 P-loop containing dynein motor region Bac_luciferase PF00296.20 KFX93207.1 - 2.1e-60 204.8 0.0 2.8e-60 204.4 0.0 1.1 1 0 0 1 1 1 1 Luciferase-like monooxygenase MFS_1 PF07690.16 KFX93208.1 - 3.1e-31 108.6 25.5 3.1e-31 108.6 25.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1 PF07690.16 KFX93209.1 - 8.7e-25 87.4 22.4 8.7e-25 87.4 22.4 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily FMO-like PF00743.19 KFX93210.1 - 1.5e-17 63.3 0.5 3.6e-17 62.0 0.1 1.8 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.6 KFX93210.1 - 4e-11 43.0 0.0 1.3e-10 41.4 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KFX93210.1 - 2.6e-10 40.0 0.0 1e-07 31.5 0.0 2.5 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KFX93210.1 - 5e-07 29.3 1.4 2.4e-06 27.0 1.4 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KFX93210.1 - 1.4e-06 28.2 1.4 1.8e-05 24.5 0.4 2.8 1 1 0 2 2 2 1 FAD dependent oxidoreductase K_oxygenase PF13434.6 KFX93210.1 - 1.9e-05 24.0 0.1 0.00014 21.1 0.0 2.0 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Thi4 PF01946.17 KFX93210.1 - 0.002 17.4 0.8 0.0034 16.7 0.1 1.6 2 0 0 2 2 2 1 Thi4 family NAD_binding_9 PF13454.6 KFX93210.1 - 0.0066 16.4 0.1 0.25 11.3 0.0 2.8 3 0 0 3 3 3 1 FAD-NAD(P)-binding Mqo PF06039.15 KFX93210.1 - 0.2 10.2 0.6 1.5 7.3 0.1 2.0 2 0 0 2 2 2 0 Malate:quinone oxidoreductase (Mqo) DUF842 PF05811.13 KFX93218.1 - 0.025 14.3 0.1 0.074 12.7 0.1 1.8 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF842) Tup_N PF08581.10 KFX93218.1 - 0.16 12.3 0.4 0.57 10.5 0.4 1.9 1 0 0 1 1 1 0 Tup N-terminal ABC_tran PF00005.27 KFX93219.1 - 3.4e-42 144.2 0.0 4.8e-21 75.7 0.0 2.6 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 KFX93219.1 - 1.3e-10 41.4 12.1 3.9e-06 26.7 1.1 2.7 2 1 0 2 2 2 2 ABC transporter transmembrane region T2SSE PF00437.20 KFX93219.1 - 4.6e-10 39.0 0.2 0.00047 19.3 0.0 2.3 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_29 PF13555.6 KFX93219.1 - 1.3e-08 34.5 0.8 0.0024 17.6 0.0 3.0 2 0 0 2 2 2 2 P-loop containing region of AAA domain SMC_N PF02463.19 KFX93219.1 - 1.9e-08 34.0 0.8 0.0029 17.1 0.0 3.9 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 KFX93219.1 - 3e-08 33.8 0.4 0.22 11.3 0.0 3.5 2 1 0 3 3 3 3 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 KFX93219.1 - 1.1e-07 32.2 0.1 0.02 15.2 0.0 2.9 3 0 0 3 3 2 2 AAA domain AAA_16 PF13191.6 KFX93219.1 - 1.2e-06 29.1 0.4 0.042 14.2 0.0 2.9 2 0 0 2 2 2 2 AAA ATPase domain FtsK_SpoIIIE PF01580.18 KFX93219.1 - 4.3e-06 26.3 0.1 0.014 14.8 0.0 2.3 2 0 0 2 2 2 2 FtsK/SpoIIIE family RsgA_GTPase PF03193.16 KFX93219.1 - 7.7e-06 25.9 1.1 0.08 12.8 0.1 2.4 2 0 0 2 2 2 2 RsgA GTPase AAA_33 PF13671.6 KFX93219.1 - 1.2e-05 25.6 0.0 0.19 11.9 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_23 PF13476.6 KFX93219.1 - 3.2e-05 24.5 0.3 0.096 13.2 0.0 2.3 2 0 0 2 2 2 2 AAA domain MMR_HSR1 PF01926.23 KFX93219.1 - 5.3e-05 23.3 0.1 0.23 11.5 0.0 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase cobW PF02492.19 KFX93219.1 - 7.5e-05 22.4 2.3 0.035 13.7 0.1 2.4 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain NTPase_1 PF03266.15 KFX93219.1 - 0.00035 20.5 0.2 0.27 11.1 0.0 2.5 2 0 0 2 2 2 1 NTPase AAA_18 PF13238.6 KFX93219.1 - 0.00065 20.3 0.2 2.5 8.7 0.2 2.8 2 0 0 2 2 2 2 AAA domain Zeta_toxin PF06414.12 KFX93219.1 - 0.0011 18.2 0.3 1.5 8.0 0.0 2.4 2 0 0 2 2 2 2 Zeta toxin Adeno_IVa2 PF02456.15 KFX93219.1 - 0.0013 17.7 0.2 0.083 11.7 0.1 2.2 2 0 0 2 2 2 1 Adenovirus IVa2 protein AAA_7 PF12775.7 KFX93219.1 - 0.0014 18.2 0.5 0.53 9.8 0.1 2.4 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_30 PF13604.6 KFX93219.1 - 0.0018 18.0 0.0 0.41 10.3 0.1 2.5 2 0 0 2 2 2 1 AAA domain Dynamin_N PF00350.23 KFX93219.1 - 0.002 18.2 0.5 1.4 9.0 0.0 2.4 2 0 0 2 2 2 1 Dynamin family AAA_14 PF13173.6 KFX93219.1 - 0.0022 18.0 0.0 3.4 7.7 0.0 3.3 3 0 0 3 3 3 1 AAA domain ABC_ATPase PF09818.9 KFX93219.1 - 0.0022 16.8 1.8 0.46 9.2 0.0 3.5 4 0 0 4 4 4 1 Predicted ATPase of the ABC class ATPase_2 PF01637.18 KFX93219.1 - 0.0025 17.8 0.1 3.8 7.4 0.0 3.1 3 0 0 3 3 3 0 ATPase domain predominantly from Archaea AAA_25 PF13481.6 KFX93219.1 - 0.0038 16.8 0.6 0.58 9.7 0.1 2.4 2 0 0 2 2 2 1 AAA domain AAA_24 PF13479.6 KFX93219.1 - 0.0042 16.8 0.1 0.52 10.0 0.0 2.5 2 0 0 2 2 2 1 AAA domain Viral_helicase1 PF01443.18 KFX93219.1 - 0.0056 16.5 0.1 3.2 7.4 0.0 2.5 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase NACHT PF05729.12 KFX93219.1 - 0.0083 16.1 2.9 2.2 8.2 0.1 2.8 3 0 0 3 3 2 1 NACHT domain DEAD PF00270.29 KFX93219.1 - 0.0094 15.7 0.0 0.98 9.2 0.0 2.5 2 0 0 2 2 2 1 DEAD/DEAH box helicase TsaE PF02367.17 KFX93219.1 - 0.0097 15.9 0.7 1.3 9.1 0.0 2.5 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE Mg_chelatase PF01078.21 KFX93219.1 - 0.01 15.2 0.1 3.4 7.0 0.0 2.3 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.22 KFX93219.1 - 0.019 15.4 0.0 6.4 7.2 0.0 2.7 2 0 0 2 2 2 0 RNA helicase Pox_A32 PF04665.12 KFX93219.1 - 0.02 14.3 0.3 3.6 7.0 0.1 2.5 2 0 0 2 2 2 0 Poxvirus A32 protein DUF815 PF05673.13 KFX93219.1 - 0.022 14.0 0.3 4.5 6.4 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) ATP_bind_1 PF03029.17 KFX93219.1 - 0.027 14.3 0.4 7.1 6.3 0.0 2.3 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_5 PF07728.14 KFX93219.1 - 0.049 13.6 1.6 20 5.2 0.1 3.6 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) Rad17 PF03215.15 KFX93219.1 - 0.051 13.5 1.2 2.8 7.8 0.0 2.9 3 0 0 3 3 2 0 Rad17 P-loop domain TrwB_AAD_bind PF10412.9 KFX93219.1 - 0.056 12.4 0.5 4.5 6.1 0.1 2.2 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain IstB_IS21 PF01695.17 KFX93219.1 - 0.057 13.2 0.7 4 7.1 0.0 3.0 3 0 0 3 3 2 0 IstB-like ATP binding protein Septin PF00735.18 KFX93219.1 - 0.07 12.4 0.2 1.9 7.7 0.0 2.2 2 0 0 2 2 2 0 Septin dNK PF01712.19 KFX93219.1 - 0.073 12.9 0.7 3.2 7.6 0.1 2.3 2 0 0 2 2 2 0 Deoxynucleoside kinase AAA PF00004.29 KFX93219.1 - 0.081 13.3 0.2 3.7 8.0 0.0 2.9 3 0 0 3 3 2 0 ATPase family associated with various cellular activities (AAA) PduV-EutP PF10662.9 KFX93219.1 - 0.1 12.3 1.1 16 5.2 0.3 2.8 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation DAP3 PF10236.9 KFX93219.1 - 0.12 11.6 1.4 2.4 7.2 0.1 2.2 2 0 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 APS_kinase PF01583.20 KFX93219.1 - 0.15 12.0 0.8 3.2 7.6 0.1 2.4 2 0 0 2 2 2 0 Adenylylsulphate kinase AAA_19 PF13245.6 KFX93219.1 - 0.17 12.2 0.4 13 6.1 0.1 2.6 2 0 0 2 2 2 0 AAA domain SbcCD_C PF13558.6 KFX93219.1 - 0.17 12.1 0.6 2.1 8.7 0.5 2.8 2 1 0 2 2 1 0 Putative exonuclease SbcCD, C subunit AAA_11 PF13086.6 KFX93219.1 - 0.17 11.6 0.1 1.3 8.8 0.0 2.1 2 0 0 2 2 2 0 AAA domain DUF2075 PF09848.9 KFX93219.1 - 0.18 11.0 0.0 6.5 5.9 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA_15 PF13175.6 KFX93219.1 - 0.19 11.4 0.3 6.3 6.4 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain DUF87 PF01935.17 KFX93219.1 - 0.38 10.8 1.9 1.8 8.6 0.2 2.2 2 0 0 2 2 2 0 Helicase HerA, central domain NB-ARC PF00931.22 KFX93219.1 - 0.44 9.7 2.0 19 4.3 0.1 2.6 3 0 0 3 3 2 0 NB-ARC domain AAA_28 PF13521.6 KFX93219.1 - 0.78 10.0 1.9 5.3 7.3 0.1 2.4 2 0 0 2 2 2 0 AAA domain DUF3176 PF11374.8 KFX93220.1 - 1e-25 90.0 3.1 2.9e-25 88.5 3.1 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF3176) SPATA9 PF15824.5 KFX93220.1 - 0.071 12.4 0.1 0.52 9.6 0.0 2.0 2 0 0 2 2 2 0 Spermatogenesis-associated protein 9 Fungal_trans PF04082.18 KFX93224.1 - 1.8e-17 63.2 0.0 3.1e-17 62.5 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KFX93224.1 - 1.4e-08 34.7 11.8 1.4e-08 34.7 11.8 1.7 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pkinase PF00069.25 KFX93225.1 - 9e-09 35.1 0.0 9.5e-09 35.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFX93225.1 - 0.00015 21.2 0.0 0.00015 21.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 KFX93225.1 - 0.0021 17.4 0.0 0.003 16.9 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KFX93225.1 - 0.012 15.5 0.0 0.017 15.1 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kinase-like PF14531.6 KFX93225.1 - 0.082 12.2 0.0 0.12 11.7 0.0 1.2 1 0 0 1 1 1 0 Kinase-like DUF1192 PF06698.11 KFX93225.1 - 0.092 12.8 0.0 0.15 12.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1192) MIP PF00230.20 KFX93226.1 - 3.2e-45 154.6 13.9 4.2e-45 154.2 13.9 1.1 1 0 0 1 1 1 1 Major intrinsic protein AAA_33 PF13671.6 KFX93227.1 - 2.4e-12 47.2 0.0 3.2e-12 46.8 0.0 1.2 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 KFX93227.1 - 1.6e-10 40.6 0.0 2.8e-10 39.8 0.0 1.3 1 0 0 1 1 1 1 Zeta toxin AAA_18 PF13238.6 KFX93227.1 - 2.4e-06 28.1 0.0 3.3e-05 24.4 0.0 2.1 1 1 1 2 2 2 1 AAA domain AAA_17 PF13207.6 KFX93227.1 - 0.0004 20.8 0.0 0.0025 18.3 0.0 2.0 1 1 1 2 2 2 1 AAA domain CoaE PF01121.20 KFX93227.1 - 0.00056 19.6 0.0 0.001 18.8 0.0 1.4 1 0 0 1 1 1 1 Dephospho-CoA kinase AAA_28 PF13521.6 KFX93227.1 - 0.00085 19.6 0.0 0.00099 19.4 0.0 1.4 1 1 0 1 1 1 1 AAA domain APS_kinase PF01583.20 KFX93227.1 - 0.0021 18.0 0.0 0.0029 17.5 0.0 1.2 1 0 0 1 1 1 1 Adenylylsulphate kinase SKI PF01202.22 KFX93227.1 - 0.0077 16.4 0.0 0.011 15.9 0.0 1.3 1 0 0 1 1 1 1 Shikimate kinase Viral_helicase1 PF01443.18 KFX93227.1 - 0.024 14.4 0.0 0.4 10.4 0.0 2.1 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase dNK PF01712.19 KFX93227.1 - 0.025 14.5 0.0 0.035 13.9 0.0 1.2 1 0 0 1 1 1 0 Deoxynucleoside kinase KTI12 PF08433.10 KFX93227.1 - 0.025 14.0 0.0 0.051 13.0 0.0 1.5 2 0 0 2 2 2 0 Chromatin associated protein KTI12 AAA PF00004.29 KFX93227.1 - 0.029 14.8 0.0 0.079 13.4 0.0 1.8 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Cytidylate_kin2 PF13189.6 KFX93227.1 - 0.043 14.0 0.0 0.072 13.2 0.0 1.5 2 0 0 2 2 2 0 Cytidylate kinase-like family CPT PF07931.12 KFX93227.1 - 0.063 13.1 1.4 2.7 7.8 0.6 2.8 1 1 1 2 2 2 0 Chloramphenicol phosphotransferase-like protein AAA_16 PF13191.6 KFX93227.1 - 0.075 13.4 0.1 0.094 13.1 0.1 1.5 1 1 0 1 1 1 0 AAA ATPase domain RNA_helicase PF00910.22 KFX93227.1 - 0.17 12.2 0.0 0.27 11.7 0.0 1.5 1 0 0 1 1 1 0 RNA helicase TauD PF02668.16 KFX93228.1 - 4.4e-36 125.1 0.1 6.4e-36 124.5 0.1 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family MFS_1 PF07690.16 KFX93229.1 - 2.3e-15 56.4 28.8 3e-15 56.0 25.9 2.0 2 0 0 2 2 2 1 Major Facilitator Superfamily UNC-93 PF05978.16 KFX93229.1 - 5.6e-09 35.9 5.7 1.3e-08 34.7 5.7 1.6 1 0 0 1 1 1 1 Ion channel regulatory protein UNC-93 Sugar_tr PF00083.24 KFX93229.1 - 0.00044 19.2 5.6 0.00044 19.2 5.6 1.7 2 0 0 2 2 2 1 Sugar (and other) transporter Ribosomal_L2_C PF03947.18 KFX93232.1 - 1.2e-50 170.9 3.3 2.3e-50 170.0 2.6 1.9 2 0 0 2 2 2 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.23 KFX93232.1 - 5.7e-25 87.1 0.2 1.6e-24 85.6 0.2 1.8 2 0 0 2 2 2 1 Ribosomal Proteins L2, RNA binding domain Cyclin_N PF00134.23 KFX93233.1 - 5.3e-45 152.2 0.1 9.3e-44 148.2 0.1 2.2 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 KFX93233.1 - 1.4e-36 125.1 0.0 3e-36 124.1 0.0 1.6 1 0 0 1 1 1 1 Cyclin, C-terminal domain PEMT PF04191.13 KFX93234.1 - 3.7e-33 114.1 3.5 4e-33 114.0 2.3 1.7 2 0 0 2 2 2 1 Phospholipid methyltransferase PH_10 PF15411.6 KFX93239.1 - 5.8e-27 94.4 0.1 2.5e-26 92.4 0.1 2.0 1 1 0 1 1 1 1 Pleckstrin homology domain VWA PF00092.28 KFX93239.1 - 1.1e-13 51.9 0.0 1.6e-13 51.3 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_3 PF13768.6 KFX93239.1 - 8.2e-11 42.1 0.0 1.7e-10 41.0 0.0 1.6 1 0 0 1 1 1 1 von Willebrand factor type A domain zf-RING_2 PF13639.6 KFX93239.1 - 6.9e-05 23.1 4.0 0.00012 22.3 4.0 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 KFX93239.1 - 0.00073 19.5 4.5 0.0012 18.7 4.5 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 KFX93239.1 - 0.0012 18.7 3.7 0.0021 17.9 3.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 KFX93239.1 - 0.0032 17.0 2.1 0.0061 16.2 2.1 1.3 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-rbx1 PF12678.7 KFX93239.1 - 0.0056 16.9 1.8 0.013 15.8 1.8 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 KFX93239.1 - 0.0067 16.3 3.5 0.012 15.5 3.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KFX93239.1 - 0.013 15.4 1.4 0.024 14.5 1.4 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) PH PF00169.29 KFX93239.1 - 0.046 14.2 0.0 0.12 12.9 0.0 1.7 1 0 0 1 1 1 0 PH domain zf-RING_11 PF17123.5 KFX93239.1 - 0.092 12.5 2.8 0.23 11.2 2.8 1.7 1 0 0 1 1 1 0 RING-like zinc finger zf-RING-like PF08746.11 KFX93239.1 - 0.24 11.8 3.6 0.45 10.9 3.6 1.5 1 0 0 1 1 1 0 RING-like domain Prok-RING_4 PF14447.6 KFX93239.1 - 0.86 9.5 2.3 1.6 8.6 2.3 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-C3H2C3 PF17122.5 KFX93239.1 - 0.86 9.7 4.1 2.1 8.5 4.1 1.7 1 1 0 1 1 1 0 Zinc-finger Fungal_trans PF04082.18 KFX93242.1 - 3e-37 128.1 0.0 5.9e-37 127.1 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KFX93242.1 - 1e-07 31.9 8.4 1.7e-07 31.2 8.4 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CAV_VP3 PF04771.12 KFX93242.1 - 0.23 11.6 6.5 0.54 10.4 6.5 1.6 1 0 0 1 1 1 0 Chicken anaemia virus VP-3 protein PigN PF04987.14 KFX93247.1 - 6.4e-164 546.1 24.5 9.3e-164 545.6 24.5 1.2 1 0 0 1 1 1 1 Phosphatidylinositolglycan class N (PIG-N) Csm1 PF12539.8 KFX93247.1 - 4.1e-33 113.9 0.1 9.1e-33 112.7 0.1 1.6 1 0 0 1 1 1 1 Chromosome segregation protein Csm1/Pcs1 Phosphodiest PF01663.22 KFX93247.1 - 4e-11 43.1 3.3 2.5e-09 37.2 3.3 2.3 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.23 KFX93247.1 - 1.1e-07 31.6 0.0 2e-07 30.8 0.0 1.4 1 0 0 1 1 1 1 Sulfatase Metalloenzyme PF01676.18 KFX93247.1 - 0.00087 18.7 0.0 0.0014 18.0 0.0 1.2 1 0 0 1 1 1 1 Metalloenzyme superfamily DUF5094 PF17015.5 KFX93247.1 - 0.12 12.4 0.0 0.3 11.2 0.0 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF5094) ABC_tran PF00005.27 KFX93249.1 - 2.5e-34 118.7 0.0 5.2e-24 85.3 0.0 2.4 2 0 0 2 2 2 2 ABC transporter ABC2_membrane PF01061.24 KFX93249.1 - 3.1e-31 108.4 14.9 8.3e-27 94.0 8.7 2.4 2 0 0 2 2 2 2 ABC-2 type transporter AAA_21 PF13304.6 KFX93249.1 - 2.6e-12 47.2 0.1 0.00071 19.5 0.0 3.3 3 0 0 3 3 3 3 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 KFX93249.1 - 1.8e-05 24.3 0.0 0.047 13.1 0.0 3.2 3 0 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 KFX93249.1 - 0.00011 22.7 0.1 0.00019 22.0 0.1 1.2 1 0 0 1 1 1 1 AAA domain SbcCD_C PF13558.6 KFX93249.1 - 0.00099 19.3 0.8 2.3 8.5 0.1 3.6 2 2 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_16 PF13191.6 KFX93249.1 - 0.0017 18.8 0.0 0.0041 17.5 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.6 KFX93249.1 - 0.0035 17.0 0.1 0.0086 15.8 0.1 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 KFX93249.1 - 0.0063 16.4 0.0 0.012 15.5 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase AAA_22 PF13401.6 KFX93249.1 - 0.0065 16.7 0.0 0.022 15.1 0.0 1.9 1 0 0 1 1 1 1 AAA domain PDR_assoc PF08370.11 KFX93249.1 - 0.02 14.6 0.2 0.082 12.7 0.1 2.1 2 0 0 2 2 2 0 Plant PDR ABC transporter associated AAA_25 PF13481.6 KFX93249.1 - 0.081 12.5 0.1 0.36 10.4 0.1 2.0 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.6 KFX93249.1 - 0.13 12.5 0.0 0.27 11.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain Pribosyltran PF00156.27 KFX93251.1 - 2.9e-17 62.7 0.0 4.3e-17 62.1 0.0 1.2 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.6 KFX93251.1 - 0.031 13.7 0.0 0.049 13.1 0.0 1.3 1 0 0 1 1 1 0 Uracil phosphoribosyltransferase GST_C_3 PF14497.6 KFX93260.1 - 8.5e-14 51.6 1.1 1.2e-13 51.1 0.5 1.5 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 KFX93260.1 - 6.6e-12 45.6 1.4 8.6e-12 45.2 0.1 1.9 3 0 0 3 3 3 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 KFX93260.1 - 7.3e-12 45.5 0.0 1.8e-11 44.2 0.0 1.6 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 KFX93260.1 - 9.6e-11 41.8 0.2 1.6e-10 41.1 0.2 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 KFX93260.1 - 5e-09 36.0 0.0 9.1e-09 35.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 KFX93260.1 - 3.1e-08 33.8 0.0 6.9e-08 32.7 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_6 PF17171.4 KFX93260.1 - 0.17 11.7 0.0 0.35 10.7 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Spo7 PF03907.13 KFX93261.1 - 1.4e-95 318.9 0.0 2.5e-95 318.2 0.0 1.4 1 0 0 1 1 1 1 Spo7-like protein Abhydrolase_1 PF00561.20 KFX93262.1 - 3.3e-19 69.5 0.0 5.8e-18 65.5 0.0 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KFX93262.1 - 1.2e-14 55.4 0.9 4.4e-14 53.6 0.0 2.2 2 1 0 2 2 2 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KFX93262.1 - 4e-14 52.5 0.0 1.5e-13 50.6 0.0 1.9 2 0 0 2 2 2 1 Serine aminopeptidase, S33 DUF915 PF06028.11 KFX93262.1 - 1e-05 25.0 0.0 1.8e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF915) Esterase PF00756.20 KFX93262.1 - 1.7e-05 24.6 0.0 3.5e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 Putative esterase Chlorophyllase2 PF12740.7 KFX93262.1 - 0.0017 17.3 0.0 0.003 16.5 0.0 1.4 1 0 0 1 1 1 1 Chlorophyllase enzyme PGAP1 PF07819.13 KFX93262.1 - 0.03 14.0 0.0 0.057 13.1 0.0 1.4 1 0 0 1 1 1 0 PGAP1-like protein Abhydrolase_3 PF07859.13 KFX93262.1 - 0.033 14.0 0.0 0.97 9.2 0.0 2.8 3 1 0 3 3 3 0 alpha/beta hydrolase fold Chlorophyllase PF07224.11 KFX93262.1 - 0.039 13.0 0.0 0.056 12.4 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase Thioesterase PF00975.20 KFX93262.1 - 0.075 13.1 0.0 0.17 12.0 0.0 1.6 1 0 0 1 1 1 0 Thioesterase domain Abhydrolase_5 PF12695.7 KFX93262.1 - 0.085 12.6 0.0 0.18 11.6 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_2 PF02230.16 KFX93262.1 - 0.12 12.1 0.0 4.3 7.1 0.0 2.3 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase G-alpha PF00503.20 KFX93263.1 - 6.5e-109 364.3 0.0 7.5e-109 364.1 0.0 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 KFX93263.1 - 9.8e-15 54.4 0.6 8e-10 38.4 0.1 2.6 2 1 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.12 KFX93263.1 - 0.00015 21.2 0.4 0.41 10.0 0.0 2.2 2 0 0 2 2 2 2 Gtr1/RagA G protein conserved region Roc PF08477.13 KFX93263.1 - 0.011 15.9 0.1 1 9.6 0.1 2.3 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_29 PF13555.6 KFX93263.1 - 0.051 13.3 0.0 0.097 12.4 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain Phosphorylase PF00343.20 KFX93264.1 - 0 1052.6 0.0 0 1052.4 0.0 1.0 1 0 0 1 1 1 1 Carbohydrate phosphorylase AAA PF00004.29 KFX93267.1 - 7.9e-11 42.5 0.0 2.1e-10 41.1 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 KFX93267.1 - 0.00014 21.6 0.0 0.00034 20.4 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 KFX93267.1 - 0.00031 20.7 0.0 0.00072 19.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Rad17 PF03215.15 KFX93267.1 - 0.00034 20.6 0.0 0.0011 19.0 0.0 1.8 2 0 0 2 2 2 1 Rad17 P-loop domain AAA_22 PF13401.6 KFX93267.1 - 0.00038 20.7 0.0 0.0013 19.0 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KFX93267.1 - 0.016 15.6 0.0 0.061 13.7 0.0 2.0 1 0 0 1 1 1 0 AAA ATPase domain AAA_14 PF13173.6 KFX93267.1 - 0.03 14.4 0.0 0.12 12.4 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 KFX93267.1 - 0.057 13.6 0.1 0.2 11.8 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 KFX93267.1 - 0.077 12.7 0.0 0.19 11.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 KFX93267.1 - 0.099 12.5 0.0 0.23 11.4 0.0 1.6 1 0 0 1 1 1 0 NTPase AAA_7 PF12775.7 KFX93267.1 - 0.13 11.7 0.0 0.27 10.7 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region Fungal_trans PF04082.18 KFX93268.1 - 1e-22 80.5 2.9 1e-22 80.5 2.9 1.8 1 1 1 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KFX93268.1 - 3.4e-08 33.5 8.8 6.2e-08 32.6 8.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fis1_TPR_C PF14853.6 KFX93269.1 - 1.2e-23 82.9 0.5 2.6e-23 81.8 0.5 1.6 1 0 0 1 1 1 1 Fis1 C-terminal tetratricopeptide repeat Fis1_TPR_N PF14852.6 KFX93269.1 - 3.5e-17 61.8 0.1 7.2e-17 60.8 0.1 1.6 1 0 0 1 1 1 1 Fis1 N-terminal tetratricopeptide repeat zf-RING_2 PF13639.6 KFX93269.1 - 2.3e-13 50.2 15.6 3.1e-13 49.8 7.0 2.3 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_3 PF13920.6 KFX93269.1 - 1.5e-09 37.6 8.2 5e-08 32.7 2.6 2.2 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 KFX93269.1 - 2e-09 37.0 2.9 2e-09 37.0 2.9 1.8 2 0 0 2 2 2 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 KFX93269.1 - 8.3e-09 35.2 6.3 8.3e-09 35.2 6.3 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 KFX93269.1 - 3.5e-07 30.4 5.1 3.5e-07 30.4 5.1 2.3 2 0 0 2 2 2 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 KFX93269.1 - 2e-06 27.6 3.1 2e-06 27.6 3.1 2.3 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4 PF00097.25 KFX93269.1 - 5.8e-06 26.1 14.4 2.4e-05 24.1 5.1 2.3 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KFX93269.1 - 3.8e-05 23.6 1.9 3.8e-05 23.6 1.9 2.4 2 0 0 2 2 2 1 RING-type zinc-finger HypA PF01155.19 KFX93269.1 - 0.00013 21.9 3.6 0.00028 20.9 0.1 2.3 2 0 0 2 2 2 1 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Prok-RING_4 PF14447.6 KFX93269.1 - 0.00015 21.5 3.7 0.00015 21.5 3.7 2.3 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-ANAPC11 PF12861.7 KFX93269.1 - 0.0059 16.6 1.6 0.0059 16.6 1.6 1.7 2 0 0 2 2 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zinc_ribbon_9 PF14369.6 KFX93269.1 - 0.0081 16.4 3.6 0.0081 16.4 3.6 2.4 2 0 0 2 2 2 1 zinc-ribbon DUF1272 PF06906.11 KFX93269.1 - 0.0082 16.2 7.1 0.49 10.5 0.3 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF1272) TPR_2 PF07719.17 KFX93269.1 - 0.012 15.6 0.6 0.031 14.4 0.6 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat Zn_ribbon_17 PF17120.5 KFX93269.1 - 0.053 13.2 12.8 0.03 14.0 6.5 2.2 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type Baculo_RING PF05883.11 KFX93269.1 - 0.17 11.9 1.2 0.6 10.1 0.2 2.0 2 0 0 2 2 2 0 Baculovirus U-box/Ring-like domain zinc_ribbon_16 PF17034.5 KFX93269.1 - 0.41 10.9 2.4 0.7 10.1 1.4 1.8 2 0 0 2 2 2 0 Zinc-ribbon like family zf-C3HC4_4 PF15227.6 KFX93269.1 - 1.1 9.5 13.8 3.7 7.8 1.1 2.5 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-UDP PF14569.6 KFX93269.1 - 1.5 9.0 4.8 3.2 7.9 0.6 2.4 2 0 0 2 2 2 0 Zinc-binding RING-finger DUF3915 PF13054.6 KFX93269.1 - 2.2 8.3 3.9 4.6 7.2 3.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3915) PHD PF00628.29 KFX93269.1 - 2.8 7.9 13.8 1.2 9.0 5.8 2.5 2 0 0 2 2 2 0 PHD-finger zinc-ribbons_6 PF07191.12 KFX93269.1 - 4.6 7.3 9.0 2 8.4 0.8 2.4 2 1 0 2 2 2 0 zinc-ribbons RINGv PF12906.7 KFX93269.1 - 8.5 6.6 15.3 0.68 10.1 8.1 2.3 2 0 0 2 2 2 0 RING-variant domain Spc24 PF08286.11 KFX93270.1 - 5.6e-34 116.6 5.1 1.5e-32 112.0 0.1 2.1 2 0 0 2 2 2 1 Spc24 subunit of Ndc80 Prefoldin_2 PF01920.20 KFX93270.1 - 0.00031 20.6 4.5 0.17 11.9 0.2 2.3 2 0 0 2 2 2 2 Prefoldin subunit Lipoprotein_16 PF03923.13 KFX93270.1 - 0.002 17.8 1.7 0.0032 17.1 1.1 1.6 2 0 0 2 2 2 1 Uncharacterized lipoprotein FlaC_arch PF05377.11 KFX93270.1 - 0.019 15.4 4.9 1 9.8 0.4 2.9 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) APG6_N PF17675.1 KFX93270.1 - 0.037 14.6 10.6 0.051 14.1 10.6 1.2 1 0 0 1 1 1 0 Apg6 coiled-coil region FapA PF03961.13 KFX93270.1 - 0.043 12.4 2.3 0.052 12.1 2.3 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A DUF1635 PF07795.11 KFX93270.1 - 0.079 12.8 4.6 0.1 12.5 4.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1635) Troponin PF00992.20 KFX93270.1 - 0.087 13.1 3.3 0.14 12.5 3.3 1.3 1 0 0 1 1 1 0 Troponin Med30 PF11315.8 KFX93270.1 - 0.094 12.9 3.6 0.14 12.4 3.6 1.2 1 0 0 1 1 1 0 Mediator complex subunit 30 TPR_MLP1_2 PF07926.12 KFX93270.1 - 0.15 12.1 10.7 0.49 10.5 10.7 1.7 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein Noelin-1 PF12308.8 KFX93270.1 - 1.6 8.8 4.6 1.5 8.9 1.8 2.1 1 1 1 2 2 2 0 Neurogenesis glycoprotein Nup54 PF13874.6 KFX93270.1 - 3 7.9 9.6 7.5 6.7 9.6 1.7 1 1 0 1 1 1 0 Nucleoporin complex subunit 54 Syntaxin-6_N PF09177.11 KFX93270.1 - 3.4 8.3 9.5 3.6 8.2 2.7 2.3 1 1 1 2 2 2 0 Syntaxin 6, N-terminal Uso1_p115_C PF04871.13 KFX93270.1 - 3.8 7.9 10.9 13 6.2 10.9 1.8 1 1 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region DEADboxA PF12343.8 KFX93271.1 - 0.038 14.5 2.4 0.097 13.2 2.4 1.7 1 0 0 1 1 1 0 Cold shock protein DEAD box A Avl9 PF09794.9 KFX93273.1 - 3.7e-145 483.4 0.0 5.1e-145 482.9 0.0 1.2 1 0 0 1 1 1 1 Transport protein Avl9 End3 PF12761.7 KFX93273.1 - 2.7e-77 259.4 0.5 5.1e-77 258.6 0.5 1.5 1 0 0 1 1 1 1 Actin cytoskeleton-regulatory complex protein END3 EF-hand_4 PF12763.7 KFX93273.1 - 3.3e-51 171.6 0.0 3.1e-49 165.2 0.1 2.5 2 0 0 2 2 2 1 Cytoskeletal-regulatory complex EF hand DUF2347 PF09804.9 KFX93273.1 - 6.7e-07 29.2 0.1 2.1e-05 24.3 0.1 2.7 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2347) EF-hand_1 PF00036.32 KFX93273.1 - 6.7e-07 28.4 0.3 6.7e-07 28.4 0.3 2.7 3 0 0 3 3 3 1 EF hand EF-hand_7 PF13499.6 KFX93273.1 - 5.8e-06 26.7 0.1 4.7e-05 23.7 0.0 2.5 2 0 0 2 2 2 1 EF-hand domain pair SPA PF08616.10 KFX93273.1 - 8.5e-06 25.7 0.0 0.0016 18.4 0.0 2.4 2 0 0 2 2 2 1 Stabilization of polarity axis EF-hand_8 PF13833.6 KFX93273.1 - 0.00016 21.4 3.9 0.00019 21.2 0.1 2.9 4 0 0 4 4 4 1 EF-hand domain pair EF-hand_6 PF13405.6 KFX93273.1 - 0.00048 19.9 0.6 0.0029 17.4 0.2 2.4 2 0 0 2 2 2 1 EF-hand domain EF-hand_5 PF13202.6 KFX93273.1 - 0.023 14.2 0.1 0.1 12.1 0.1 2.1 1 0 0 1 1 1 0 EF hand Atg14 PF10186.9 KFX93273.1 - 0.23 10.5 2.2 0.47 9.5 2.2 1.4 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Spc7 PF08317.11 KFX93273.1 - 1.4 7.7 6.7 3.5 6.4 6.7 1.6 1 1 0 1 1 1 0 Spc7 kinetochore protein Zn_clus PF00172.18 KFX93274.1 - 1.2e-06 28.5 11.5 1.2e-06 28.5 11.5 1.9 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain FMN_red PF03358.15 KFX93275.1 - 2.1e-23 82.8 0.0 3.5e-23 82.1 0.0 1.2 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.17 KFX93275.1 - 4.8e-07 29.7 0.0 6.1e-07 29.3 0.0 1.2 1 0 0 1 1 1 1 Flavodoxin-like fold HK PF02110.15 KFX93277.1 - 5.9e-75 251.8 0.4 8.7e-75 251.3 0.4 1.2 1 0 0 1 1 1 1 Hydroxyethylthiazole kinase family TMP-TENI PF02581.17 KFX93277.1 - 4.6e-56 189.0 1.3 8.3e-56 188.2 1.3 1.4 1 0 0 1 1 1 1 Thiamine monophosphate synthase Carb_kinase PF01256.17 KFX93277.1 - 4.3e-06 26.4 0.4 1.8e-05 24.3 0.1 1.9 2 0 0 2 2 2 1 Carbohydrate kinase Phos_pyr_kin PF08543.12 KFX93277.1 - 0.0055 16.1 1.0 0.13 11.7 0.1 2.7 2 1 0 2 2 2 1 Phosphomethylpyrimidine kinase Peripla_BP_6 PF13458.6 KFX93277.1 - 0.01 15.5 0.3 0.57 9.8 0.0 3.1 3 1 1 4 4 4 0 Periplasmic binding protein POC3_POC4 PF10448.9 KFX93277.1 - 0.13 12.3 0.0 0.24 11.4 0.0 1.4 1 0 0 1 1 1 0 20S proteasome chaperone assembly proteins 3 and 4 eIF-5_eIF-2B PF01873.17 KFX93278.1 - 6.3e-39 132.5 0.0 1.1e-38 131.7 0.0 1.4 1 0 0 1 1 1 1 Domain found in IF2B/IF5 W2 PF02020.18 KFX93278.1 - 4e-23 81.4 0.0 1.4e-22 79.6 0.0 2.0 1 0 0 1 1 1 1 eIF4-gamma/eIF5/eIF2-epsilon Ku_C PF03730.14 KFX93278.1 - 0.16 12.7 0.4 0.16 12.7 0.4 3.0 3 0 0 3 3 3 0 Ku70/Ku80 C-terminal arm HEAT_2 PF13646.6 KFX93279.1 - 2.9e-06 27.6 1.0 4.1 7.9 0.0 5.4 5 0 0 5 5 5 3 HEAT repeats HEAT PF02985.22 KFX93279.1 - 0.00017 21.5 0.3 0.54 10.7 0.0 4.7 4 0 0 4 4 4 1 HEAT repeat SRPRB PF09439.10 KFX93280.1 - 9e-33 113.2 0.1 6.4e-32 110.4 0.1 2.0 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 KFX93280.1 - 3.9e-07 29.7 0.0 1.3e-06 28.0 0.0 1.7 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 KFX93280.1 - 5.2e-06 26.1 0.0 1.2e-05 25.0 0.0 1.7 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 KFX93280.1 - 2.9e-05 24.1 0.0 6.4e-05 23.0 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase Arf PF00025.21 KFX93280.1 - 4e-05 23.1 0.0 0.0012 18.3 0.0 2.6 2 1 0 2 2 2 1 ADP-ribosylation factor family AAA_16 PF13191.6 KFX93280.1 - 0.00022 21.7 0.7 0.00057 20.3 0.7 1.7 1 1 0 1 1 1 1 AAA ATPase domain cobW PF02492.19 KFX93280.1 - 0.0037 16.9 0.3 0.89 9.1 0.0 2.2 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain RsgA_GTPase PF03193.16 KFX93280.1 - 0.0044 16.9 1.2 1.3 8.9 0.2 3.0 2 1 0 2 2 2 1 RsgA GTPase AAA_22 PF13401.6 KFX93280.1 - 0.0095 16.2 0.0 0.017 15.4 0.0 1.5 1 1 0 1 1 1 1 AAA domain SRP54 PF00448.22 KFX93280.1 - 0.023 14.3 0.0 7.4 6.2 0.0 2.4 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain Roc PF08477.13 KFX93280.1 - 0.024 14.9 0.1 0.098 12.9 0.1 2.1 1 1 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase TniB PF05621.11 KFX93280.1 - 0.024 14.0 0.0 0.041 13.3 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein G-alpha PF00503.20 KFX93280.1 - 0.039 13.1 0.0 2.6 7.1 0.1 2.0 1 1 1 2 2 2 0 G-protein alpha subunit AAA_5 PF07728.14 KFX93280.1 - 0.041 13.9 0.1 0.33 10.9 0.0 2.1 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Septin PF00735.18 KFX93280.1 - 0.042 13.1 0.0 0.083 12.2 0.0 1.4 1 0 0 1 1 1 0 Septin ABC_tran PF00005.27 KFX93280.1 - 0.044 14.3 0.0 0.27 11.7 0.0 2.1 2 1 0 2 2 2 0 ABC transporter AAA PF00004.29 KFX93280.1 - 0.066 13.6 1.2 0.65 10.4 1.2 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_29 PF13555.6 KFX93280.1 - 0.09 12.5 0.1 0.24 11.2 0.1 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_7 PF12775.7 KFX93280.1 - 0.09 12.3 0.0 0.74 9.3 0.0 2.2 2 0 0 2 2 2 0 P-loop containing dynein motor region PduV-EutP PF10662.9 KFX93280.1 - 0.097 12.4 0.0 1.1 9.0 0.0 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Ras PF00071.22 KFX93280.1 - 0.11 12.1 0.1 5.4 6.6 0.0 2.4 2 1 0 2 2 2 0 Ras family ATP_bind_1 PF03029.17 KFX93280.1 - 0.11 12.2 0.1 5.4 6.7 0.0 2.4 2 1 0 2 2 2 0 Conserved hypothetical ATP binding protein Zeta_toxin PF06414.12 KFX93280.1 - 0.13 11.5 0.1 0.23 10.7 0.1 1.3 1 0 0 1 1 1 0 Zeta toxin AAA_21 PF13304.6 KFX93280.1 - 0.24 11.2 1.0 2.4 7.9 0.2 2.4 2 1 1 3 3 3 0 AAA domain, putative AbiEii toxin, Type IV TA system DHHC PF01529.20 KFX93281.1 - 3.1e-35 121.2 9.4 3.1e-35 121.2 9.4 2.6 2 1 0 2 2 2 1 DHHC palmitoyltransferase Ank_2 PF12796.7 KFX93281.1 - 7.4e-32 109.8 0.5 1.1e-11 45.1 0.1 3.6 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KFX93281.1 - 2.2e-21 75.9 1.2 5.2e-05 23.7 0.3 4.7 2 1 2 4 4 4 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 KFX93281.1 - 2e-19 69.4 0.8 3.4e-05 24.0 0.0 4.9 2 2 2 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFX93281.1 - 3.2e-19 67.0 3.9 2.7e-07 30.4 0.0 6.4 6 0 0 6 6 6 3 Ankyrin repeat Ank PF00023.30 KFX93281.1 - 5.6e-17 61.4 2.4 2.2e-05 24.7 0.0 6.2 6 0 0 6 6 6 3 Ankyrin repeat PocR PF10114.9 KFX93281.1 - 0.8 9.5 3.0 1.6 8.5 3.0 1.4 1 0 0 1 1 1 0 Sensory domain found in PocR Kinesin PF00225.23 KFX93282.1 - 2.3e-109 365.3 1.7 2.5e-109 365.2 0.0 1.9 2 0 0 2 2 2 1 Kinesin motor domain DUF3694 PF12473.8 KFX93282.1 - 2.9e-43 148.2 0.2 2.5e-42 145.2 0.0 2.6 2 0 0 2 2 2 1 Kinesin protein Kinesin_assoc PF16183.5 KFX93282.1 - 1.5e-34 119.7 16.9 9.2e-31 107.4 0.4 4.2 3 1 1 4 4 4 2 Kinesin-associated Microtub_bd PF16796.5 KFX93282.1 - 3e-23 82.4 0.0 9.2e-23 80.8 0.0 1.9 1 0 0 1 1 1 1 Microtubule binding PH PF00169.29 KFX93282.1 - 8.2e-06 26.3 0.0 3.6e-05 24.2 0.0 2.1 2 0 0 2 2 2 1 PH domain KIF1B PF12423.8 KFX93282.1 - 3.2e-05 24.3 0.2 0.00011 22.5 0.2 2.0 1 0 0 1 1 1 1 Kinesin protein 1B PDDEXK_1 PF12705.7 KFX93282.1 - 0.0092 15.9 1.7 0.057 13.3 1.7 2.3 1 1 0 1 1 1 1 PD-(D/E)XK nuclease superfamily AAA_22 PF13401.6 KFX93282.1 - 0.065 13.5 0.4 0.6 10.4 0.0 2.6 2 0 0 2 2 2 0 AAA domain DUF4709 PF15821.5 KFX93282.1 - 1.7 8.9 11.2 5.5 7.3 5.7 3.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4709) WW PF00397.26 KFX93286.1 - 1.1e-08 35.0 1.9 2.6e-08 33.8 1.9 1.7 1 0 0 1 1 1 1 WW domain Voldacs PF03517.13 KFX93287.1 - 1.8e-25 89.7 0.1 1.8e-25 89.7 0.1 2.5 3 1 0 3 3 3 1 Regulator of volume decrease after cellular swelling Zn_clus PF00172.18 KFX93309.1 - 5.4e-07 29.6 5.6 9.6e-07 28.8 5.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Baculo_PEP_C PF04513.12 KFX93309.1 - 0.052 13.6 0.6 0.092 12.8 0.1 1.6 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus ketoacyl-synt PF00109.26 KFX93310.1 - 4.6e-74 249.2 0.0 1.3e-73 247.7 0.0 1.9 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Condensation PF00668.20 KFX93310.1 - 7.7e-70 235.8 0.9 1.2e-69 235.2 0.9 1.3 1 0 0 1 1 1 1 Condensation domain AMP-binding PF00501.28 KFX93310.1 - 1.1e-69 235.1 0.1 3e-69 233.6 0.0 1.8 2 0 0 2 2 2 1 AMP-binding enzyme KR PF08659.10 KFX93310.1 - 5.5e-54 182.8 0.6 1.4e-51 175.0 0.0 3.8 5 0 0 5 5 4 1 KR domain PS-DH PF14765.6 KFX93310.1 - 3.2e-47 161.2 0.0 7.3e-47 160.0 0.0 1.7 1 0 0 1 1 1 1 Polyketide synthase dehydratase Acyl_transf_1 PF00698.21 KFX93310.1 - 1.6e-44 152.8 0.2 3.1e-44 151.8 0.2 1.4 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 KFX93310.1 - 7.4e-32 109.8 0.2 4.7e-31 107.2 0.0 2.6 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain NAD_binding_4 PF07993.12 KFX93310.1 - 5.6e-30 104.4 0.0 1.9e-27 96.1 0.0 2.6 1 1 0 1 1 1 1 Male sterility protein Epimerase PF01370.21 KFX93310.1 - 2.2e-20 73.2 0.0 7.8e-15 55.0 0.0 2.9 3 0 0 3 3 2 2 NAD dependent epimerase/dehydratase family PP-binding PF00550.25 KFX93310.1 - 6.7e-20 71.2 0.7 5.3e-10 39.5 0.0 3.1 2 0 0 2 2 2 2 Phosphopantetheine attachment site Methyltransf_12 PF08242.12 KFX93310.1 - 1.2e-19 70.9 0.0 5.8e-19 68.7 0.0 2.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KFX93310.1 - 1.2e-13 51.2 0.0 3.1e-13 49.9 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KFX93310.1 - 3.6e-13 50.0 0.0 2.2e-12 47.5 0.0 2.5 2 0 0 2 2 1 1 Methyltransferase domain KAsynt_C_assoc PF16197.5 KFX93310.1 - 6.5e-13 49.1 0.0 2.3e-12 47.4 0.0 2.0 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension Methyltransf_11 PF08241.12 KFX93310.1 - 6.3e-12 46.0 0.0 2.5e-11 44.1 0.0 2.2 1 0 0 1 1 1 1 Methyltransferase domain adh_short PF00106.25 KFX93310.1 - 2.7e-10 40.0 0.1 2.7e-09 36.8 0.0 2.7 3 0 0 3 3 2 1 short chain dehydrogenase GDP_Man_Dehyd PF16363.5 KFX93310.1 - 2.1e-09 37.3 0.0 0.0011 18.4 0.0 2.3 2 0 0 2 2 2 2 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 KFX93310.1 - 2.7e-09 36.4 0.0 5.1e-06 25.7 0.0 2.4 2 0 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family Methyltransf_31 PF13847.6 KFX93310.1 - 2.1e-08 34.1 0.0 6e-08 32.6 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KFX93310.1 - 2.1e-07 30.5 0.1 1e-06 28.3 0.0 2.2 3 0 0 3 3 2 1 ubiE/COQ5 methyltransferase family Thiolase_N PF00108.23 KFX93310.1 - 3.8e-05 23.2 0.0 0.00012 21.6 0.0 1.8 1 0 0 1 1 1 1 Thiolase, N-terminal domain adh_short_C2 PF13561.6 KFX93310.1 - 9.9e-05 22.0 0.0 0.00025 20.7 0.0 1.7 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase RmlD_sub_bind PF04321.17 KFX93310.1 - 0.00012 21.3 0.0 0.0061 15.7 0.0 2.4 2 0 0 2 2 2 1 RmlD substrate binding domain NAD_binding_10 PF13460.6 KFX93310.1 - 0.00081 19.3 0.0 0.14 12.0 0.0 3.0 2 0 0 2 2 2 1 NAD(P)H-binding DapB_N PF01113.20 KFX93310.1 - 0.0069 16.5 0.7 3.4 7.8 0.0 3.4 3 0 0 3 3 3 1 Dihydrodipicolinate reductase, N-terminus F420_oxidored PF03807.17 KFX93310.1 - 0.019 15.5 0.0 3.4 8.3 0.0 3.8 4 0 0 4 4 2 0 NADP oxidoreductase coenzyme F420-dependent Polysacc_synt_2 PF02719.15 KFX93310.1 - 0.024 13.7 0.0 5.1 6.2 0.0 2.5 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein Methyltransf_16 PF10294.9 KFX93310.1 - 0.03 14.1 0.0 0.11 12.2 0.0 1.9 1 0 0 1 1 1 0 Lysine methyltransferase Semialdhyde_dh PF01118.24 KFX93310.1 - 0.062 13.7 0.0 4.8 7.6 0.0 3.1 3 0 0 3 3 2 0 Semialdehyde dehydrogenase, NAD binding domain DREV PF05219.12 KFX93310.1 - 0.07 12.2 0.0 0.15 11.2 0.0 1.4 1 0 0 1 1 1 0 DREV methyltransferase Abhydrolase_1 PF00561.20 KFX93322.1 - 5.1e-14 52.5 0.0 7.1e-14 52.1 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KFX93322.1 - 4.1e-10 40.6 0.0 1.1e-09 39.2 0.0 1.7 2 1 0 2 2 2 1 Alpha/beta hydrolase family Ndr PF03096.14 KFX93322.1 - 1.4e-09 37.1 0.0 2e-09 36.5 0.0 1.1 1 0 0 1 1 1 1 Ndr family Esterase PF00756.20 KFX93322.1 - 0.00054 19.7 0.0 0.00083 19.1 0.0 1.3 1 0 0 1 1 1 1 Putative esterase Hydrolase_4 PF12146.8 KFX93322.1 - 0.0042 16.4 0.0 0.0065 15.8 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 RSN1_7TM PF02714.15 KFX93323.1 - 2.3e-78 263.3 14.3 2.3e-78 263.3 14.3 2.1 2 0 0 2 2 2 1 Calcium-dependent channel, 7TM region, putative phosphate RSN1_TM PF13967.6 KFX93323.1 - 1.3e-39 135.5 1.9 1.3e-39 135.5 1.9 2.2 2 0 0 2 2 2 1 Late exocytosis, associated with Golgi transport PHM7_cyt PF14703.6 KFX93323.1 - 2.8e-23 83.0 0.0 3.3e-22 79.5 0.0 2.1 1 1 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter PHM7_ext PF12621.8 KFX93323.1 - 1.2e-21 76.6 0.2 2.9e-21 75.5 0.2 1.6 1 0 0 1 1 1 1 Extracellular tail, of 10TM putative phosphate transporter RRM_1 PF00076.22 KFX93323.1 - 0.099 12.5 0.0 0.24 11.2 0.0 1.6 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CCDC50_N PF15295.6 KFX93323.1 - 0.17 12.1 0.5 0.27 11.4 0.5 1.2 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 50 N-terminus Questin_oxidase PF14027.6 KFX93324.1 - 8.5e-97 324.7 1.8 1e-96 324.5 1.8 1.1 1 0 0 1 1 1 1 Questin oxidase-like PBS_linker_poly PF00427.21 KFX93324.1 - 0.14 12.2 0.0 0.33 11.0 0.0 1.6 1 0 0 1 1 1 0 Phycobilisome Linker polypeptide Fungal_trans PF04082.18 KFX93327.1 - 5.4e-27 94.5 0.0 8.9e-27 93.8 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KFX93327.1 - 3.4e-11 43.1 12.2 6e-11 42.3 12.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Dynamin_M PF01031.20 KFX93332.1 - 1.2e-46 159.2 0.1 2.3e-46 158.3 0.1 1.5 1 0 0 1 1 1 1 Dynamin central region HATPase_c PF02518.26 KFX93332.1 - 6.6e-21 74.9 0.3 3e-20 72.8 0.2 2.1 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 KFX93332.1 - 1.1e-10 41.3 0.9 3.8e-10 39.7 0.1 2.5 3 0 0 3 3 3 1 His Kinase A (phospho-acceptor) domain Dynamin_N PF00350.23 KFX93332.1 - 0.093 12.8 0.1 0.35 10.9 0.0 2.0 2 0 0 2 2 2 0 Dynamin family GED PF02212.18 KFX93332.1 - 0.13 12.4 0.0 0.4 10.9 0.0 1.9 1 0 0 1 1 1 0 Dynamin GTPase effector domain HATPase_c PF02518.26 KFX93333.1 - 3.1e-26 92.1 0.0 5.5e-26 91.3 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 KFX93333.1 - 2.2e-09 37.2 0.0 8.5e-09 35.3 0.0 2.1 1 1 0 1 1 1 1 His Kinase A (phospho-acceptor) domain MEDS PF14417.6 KFX93333.1 - 9.6e-08 32.0 0.3 0.0011 18.8 0.1 2.6 2 0 0 2 2 2 2 MEDS: MEthanogen/methylotroph, DcmR Sensory domain Response_reg PF00072.24 KFX93333.1 - 7.9e-07 29.2 0.3 9.6e-06 25.7 0.3 2.4 1 1 0 1 1 1 1 Response regulator receiver domain DUF4141 PF13605.6 KFX93333.1 - 0.00012 21.2 0.1 0.00027 20.1 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4141) HATPase_c_3 PF13589.6 KFX93333.1 - 0.048 13.5 0.0 0.12 12.2 0.0 1.6 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Hemerythrin PF01814.23 KFX93334.1 - 1.6e-07 32.0 0.3 4.7e-07 30.5 0.0 2.0 2 1 0 2 2 2 1 Hemerythrin HHE cation binding domain CBM_21 PF03370.13 KFX93335.1 - 1e-30 106.2 0.4 1.8e-30 105.4 0.4 1.4 1 0 0 1 1 1 1 Carbohydrate/starch-binding module (family 21) CBM53 PF16760.5 KFX93335.1 - 5e-08 33.4 0.2 1e-07 32.4 0.2 1.5 1 0 0 1 1 1 1 Starch/carbohydrate-binding module (family 53) bZIP_1 PF00170.21 KFX93336.1 - 2.1e-08 34.1 7.2 2.1e-08 34.1 7.2 2.0 3 0 0 3 3 3 1 bZIP transcription factor bZIP_2 PF07716.15 KFX93336.1 - 7.9e-05 22.7 7.1 7.9e-05 22.7 7.1 2.3 2 0 0 2 2 2 1 Basic region leucine zipper RseA_C PF03873.13 KFX93336.1 - 0.084 13.1 0.2 0.38 11.0 0.2 2.2 1 0 0 1 1 1 0 Anti sigma-E protein RseA, C-terminal domain YlqD PF11068.8 KFX93336.1 - 5.8 7.3 7.9 8.7 6.7 2.1 2.2 2 0 0 2 2 2 0 YlqD protein Hemerythrin PF01814.23 KFX93337.1 - 1.6e-11 44.9 0.1 2.3e-11 44.4 0.1 1.2 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain POR PF01558.18 KFX93337.1 - 0.078 13.0 0.0 0.16 12.0 0.0 1.6 1 1 0 1 1 1 0 Pyruvate ferredoxin/flavodoxin oxidoreductase PH PF00169.29 KFX93338.1 - 4.2e-08 33.6 0.2 7.3e-08 32.9 0.2 1.4 1 0 0 1 1 1 1 PH domain PH_11 PF15413.6 KFX93338.1 - 0.071 13.5 1.3 0.28 11.6 1.3 1.8 1 1 0 1 1 1 0 Pleckstrin homology domain Peptidase_S55 PF05580.12 KFX93338.1 - 0.099 12.6 0.1 0.13 12.2 0.1 1.1 1 0 0 1 1 1 0 SpoIVB peptidase S55 PH_9 PF15410.6 KFX93338.1 - 0.13 12.6 0.2 0.24 11.8 0.2 1.6 1 1 0 1 1 1 0 Pleckstrin homology domain AROS PF15684.5 KFX93339.1 - 0.29 11.7 7.0 3.5 8.2 0.3 2.8 2 0 0 2 2 2 0 Active regulator of SIRT1, or 40S ribosomal protein S19-binding 1 Myb_DNA-bind_3 PF12776.7 KFX93339.1 - 0.71 10.9 0.1 0.71 10.9 0.1 3.3 3 1 1 4 4 4 0 Myb/SANT-like DNA-binding domain Myb_DNA-bind_4 PF13837.6 KFX93339.1 - 7.3 7.0 8.7 0.24 11.8 1.5 2.2 2 0 0 2 2 2 0 Myb/SANT-like DNA-binding domain RRM_1 PF00076.22 KFX93340.1 - 0.19 11.6 0.0 0.36 10.7 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) bZIP_1 PF00170.21 KFX93342.1 - 6.7e-09 35.7 7.5 6.7e-09 35.7 7.5 1.8 2 0 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.15 KFX93342.1 - 0.0013 18.8 8.9 0.003 17.6 8.9 1.7 1 0 0 1 1 1 1 Basic region leucine zipper K_channel_TID PF07941.11 KFX93342.1 - 0.031 14.7 3.2 0.076 13.5 3.2 1.6 1 0 0 1 1 1 0 Potassium channel Kv1.4 tandem inactivation domain FAM199X PF15814.5 KFX93342.1 - 0.051 12.6 9.4 0.078 12.0 9.4 1.2 1 0 0 1 1 1 0 Protein family FAM199X bZIP_Maf PF03131.17 KFX93342.1 - 0.11 13.0 12.8 0.077 13.5 9.3 2.1 1 1 1 2 2 2 0 bZIP Maf transcription factor SR-25 PF10500.9 KFX93342.1 - 0.3 10.6 19.0 0.48 10.0 19.0 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Med3 PF11593.8 KFX93342.1 - 1.1 8.4 11.9 1.5 7.9 11.9 1.3 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Grg1 PF11034.8 KFX93343.1 - 5e-29 100.3 13.6 5.5e-29 100.2 13.6 1.0 1 0 0 1 1 1 1 Glucose-repressible protein Grg1 HSP9_HSP12 PF04119.12 KFX93343.1 - 0.53 10.7 7.2 1.4 9.3 2.6 2.2 1 1 1 2 2 2 0 Heat shock protein 9/12 Hemerythrin PF01814.23 KFX93344.1 - 3.1e-10 40.8 0.2 6.7e-10 39.7 0.2 1.6 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain Pkinase PF00069.25 KFX93345.1 - 1.7e-27 96.4 0.0 2.1e-27 96.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFX93345.1 - 9.7e-16 57.8 0.0 1.2e-15 57.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KFX93345.1 - 2.2e-10 39.9 0.0 2.8e-10 39.5 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KFX93345.1 - 3.7e-05 23.8 0.2 0.0054 16.7 0.0 2.3 1 1 0 2 2 2 2 Phosphotransferase enzyme family HATPase_c PF02518.26 KFX93346.1 - 2.9e-21 76.1 0.3 6.8e-21 74.9 0.3 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 KFX93346.1 - 1.7e-19 70.0 0.0 6.1e-18 65.0 0.0 2.6 2 0 0 2 2 2 1 Response regulator receiver domain HisKA PF00512.25 KFX93346.1 - 7.5e-09 35.5 0.6 2e-08 34.2 0.2 2.0 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain Aldedh PF00171.22 KFX93374.1 - 2e-31 109.0 0.0 2.3e-31 108.8 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family JmjN PF02375.17 KFX93381.1 - 6e-06 26.1 0.2 1.2e-05 25.2 0.2 1.5 1 0 0 1 1 1 1 jmjN domain DUF4404 PF14357.6 KFX93383.1 - 0.63 10.7 5.3 2 9.1 5.3 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4404) TMCO5 PF14992.6 KFX93383.1 - 0.73 9.4 8.3 1.2 8.6 8.3 1.2 1 0 0 1 1 1 0 TMCO5 family CENP-W PF15510.6 KFX93384.1 - 7.1e-05 23.0 0.1 8.1e-05 22.8 0.1 1.1 1 0 0 1 1 1 1 CENP-W protein CBFD_NFYB_HMF PF00808.23 KFX93384.1 - 0.00017 21.8 0.0 0.00021 21.5 0.0 1.1 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone PS_Dcarbxylase PF02666.15 KFX93386.1 - 3.5e-55 186.7 0.0 5.4e-55 186.1 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase C2 PF00168.30 KFX93386.1 - 3.6e-38 130.0 0.0 9.7e-18 64.4 0.0 2.6 2 0 0 2 2 2 2 C2 domain EF-hand_6 PF13405.6 KFX93386.1 - 0.0041 16.9 0.0 0.083 12.9 0.0 3.1 2 0 0 2 2 2 1 EF-hand domain EF-hand_1 PF00036.32 KFX93386.1 - 0.0058 16.1 0.1 0.03 13.8 0.0 2.4 2 0 0 2 2 2 1 EF hand EF-hand_7 PF13499.6 KFX93386.1 - 0.013 15.9 1.5 0.067 13.7 1.5 2.3 1 1 0 1 1 1 0 EF-hand domain pair EF-hand_5 PF13202.6 KFX93386.1 - 0.075 12.6 0.0 0.33 10.5 0.0 2.2 2 0 0 2 2 2 0 EF hand PAP2_3 PF14378.6 KFX93387.1 - 3.1e-21 75.9 16.7 3.1e-21 75.9 16.7 2.0 1 1 1 2 2 2 1 PAP2 superfamily PAP2 PF01569.21 KFX93387.1 - 9.2e-11 41.7 3.2 9.2e-11 41.7 3.2 2.9 2 1 0 2 2 2 1 PAP2 superfamily PAP2_C PF14360.6 KFX93387.1 - 2.2 8.9 15.2 1.9 9.1 4.0 3.4 3 0 0 3 3 3 0 PAP2 superfamily C-terminal NAD_binding_8 PF13450.6 KFX93388.1 - 2.4e-07 30.8 1.6 6.2e-07 29.6 1.6 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.19 KFX93388.1 - 0.00024 20.5 1.5 0.00055 19.3 1.5 1.6 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 KFX93388.1 - 0.00055 19.3 0.9 0.0011 18.2 0.9 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 KFX93388.1 - 0.0023 17.3 0.1 0.0031 16.9 0.1 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KFX93388.1 - 0.008 15.3 5.3 0.063 12.3 2.8 2.1 1 1 1 2 2 2 1 FAD binding domain DAO PF01266.24 KFX93388.1 - 0.011 15.4 6.0 0.014 15.0 5.3 1.4 1 1 0 1 1 1 0 FAD dependent oxidoreductase GIDA PF01134.22 KFX93388.1 - 0.037 13.1 1.6 0.06 12.4 1.6 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A Pyr_redox PF00070.27 KFX93388.1 - 0.042 14.4 1.7 0.063 13.8 0.8 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KFX93388.1 - 0.81 8.3 3.5 0.57 8.8 2.1 1.5 2 0 0 2 2 2 0 HI0933-like protein MFS_1 PF07690.16 KFX93392.1 - 1.7e-15 56.8 38.6 2.8e-13 49.5 38.0 3.0 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 KFX93392.1 - 0.58 8.5 23.7 0.57 8.5 19.1 2.8 2 1 0 2 2 2 0 Fungal trichothecene efflux pump (TRI12) adh_short PF00106.25 KFX93393.1 - 3.2e-22 78.9 0.0 1.9e-17 63.4 0.1 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KFX93393.1 - 1.2e-10 41.3 0.0 1.9e-08 34.2 0.0 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KFX93393.1 - 3.1e-08 33.7 0.1 5.9e-08 32.8 0.1 1.3 1 0 0 1 1 1 1 KR domain Fungal_trans_2 PF11951.8 KFX93394.1 - 1e-07 31.1 3.6 7.5e-05 21.7 0.1 2.2 2 0 0 2 2 2 2 Fungal specific transcription factor domain Aldedh PF00171.22 KFX93395.1 - 2.6e-78 263.6 0.0 3.4e-78 263.2 0.0 1.1 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1542 PF07564.11 KFX93395.1 - 0.055 13.6 1.9 0.16 12.1 1.9 1.8 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1542) RNA_pol_Rpb2_1 PF04563.15 KFX93395.1 - 0.062 12.8 0.0 0.087 12.3 0.0 1.2 1 0 0 1 1 1 0 RNA polymerase beta subunit IF-2B PF01008.17 KFX93396.1 - 2.4e-19 69.6 0.1 5.6e-19 68.4 0.1 1.4 1 1 0 1 1 1 1 Initiation factor 2 subunit family NUDIX PF00293.28 KFX93396.1 - 9.5e-12 45.1 0.0 2.2e-11 43.9 0.0 1.6 1 0 0 1 1 1 1 NUDIX domain Sugar_tr PF00083.24 KFX93397.1 - 2.5e-94 316.7 24.8 3.2e-94 316.4 24.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KFX93397.1 - 1.7e-15 56.8 48.9 5.8e-11 41.9 34.8 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF3328 PF11807.8 KFX93405.1 - 4e-33 115.1 0.0 5.4e-33 114.6 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) Acetyltransf_3 PF13302.7 KFX93406.1 - 6.8e-19 68.9 0.0 8.9e-19 68.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KFX93406.1 - 3.1e-08 33.9 0.1 7.8e-07 29.3 0.0 2.1 1 1 1 2 2 2 1 Acetyltransferase (GNAT) family FR47 PF08445.10 KFX93406.1 - 0.0023 17.9 0.1 0.015 15.2 0.0 2.0 2 0 0 2 2 2 1 FR47-like protein Acetyltransf_8 PF13523.6 KFX93406.1 - 0.046 13.4 0.0 0.2 11.3 0.0 1.8 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain DUF1918 PF08940.11 KFX93408.1 - 0.072 12.7 0.0 0.13 11.9 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1918) Dimer_Tnp_hAT PF05699.14 KFX93411.1 - 4.8e-18 64.7 0.0 1.9e-17 62.8 0.0 2.1 2 0 0 2 2 2 1 hAT family C-terminal dimerisation region NAD_kinase PF01513.21 KFX93440.1 - 3.2e-74 249.7 0.0 7.9e-74 248.5 0.0 1.6 1 1 0 1 1 1 1 ATP-NAD kinase DAGK_cat PF00781.24 KFX93440.1 - 0.023 14.3 0.0 0.052 13.2 0.0 1.5 1 0 0 1 1 1 0 Diacylglycerol kinase catalytic domain Cupin_3 PF05899.12 KFX93440.1 - 0.096 12.4 0.0 5 6.9 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF861) IF-2B PF01008.17 KFX93441.1 - 2.1e-78 263.4 0.0 2.9e-78 263.0 0.0 1.2 1 0 0 1 1 1 1 Initiation factor 2 subunit family Lactamase_B PF00753.27 KFX93441.1 - 3.4e-15 56.6 4.5 5.8e-14 52.6 4.5 2.6 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily HAGH_C PF16123.5 KFX93441.1 - 1.1e-11 45.0 0.0 3.3e-11 43.5 0.0 1.8 1 0 0 1 1 1 1 Hydroxyacylglutathione hydrolase C-terminus Lactamase_B_2 PF12706.7 KFX93441.1 - 0.069 12.7 1.6 0.87 9.1 1.6 2.4 1 1 0 1 1 1 0 Beta-lactamase superfamily domain RRG8 PF17068.5 KFX93441.1 - 0.075 12.4 0.0 0.16 11.4 0.0 1.4 1 0 0 1 1 1 0 Required for respiratory growth protein 8 mitochondrial COMPASS-Shg1 PF05205.12 KFX93443.1 - 8.7e-24 84.2 0.2 8.7e-24 84.2 0.2 1.9 2 0 0 2 2 2 1 COMPASS (Complex proteins associated with Set1p) component shg1 PRCH PF03967.13 KFX93443.1 - 0.24 11.6 2.1 0.28 11.4 0.2 2.0 2 0 0 2 2 2 0 Photosynthetic reaction centre, H-chain N-terminal region UCH PF00443.29 KFX93444.1 - 4.6e-40 137.7 0.1 8.7e-40 136.8 0.0 1.5 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KFX93444.1 - 1.2e-07 31.7 0.2 5.7e-07 29.4 0.2 2.1 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Alb1 PF09135.11 KFX93445.1 - 8.8e-26 90.8 15.9 1.3e-25 90.3 15.9 1.2 1 0 0 1 1 1 1 Alb1 Las1 PF04031.13 KFX93446.1 - 2.4e-55 186.9 0.0 3.6e-55 186.3 0.0 1.3 1 0 0 1 1 1 1 Las1-like IF4E PF01652.18 KFX93447.1 - 1.5e-37 128.8 0.0 2e-37 128.4 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E DUF4598 PF15370.6 KFX93448.1 - 7.3e-19 68.3 7.8 7.3e-19 68.3 7.8 2.8 2 1 0 2 2 2 2 Domain of unknown function (DUF4598) GTP_EFTU PF00009.27 KFX93449.1 - 5.2e-56 189.3 0.1 7.1e-56 188.8 0.1 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 KFX93449.1 - 6.3e-27 94.1 0.0 1.6e-26 92.8 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 KFX93449.1 - 4.2e-19 68.7 1.7 1.1e-18 67.3 1.7 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 KFX93449.1 - 1.4e-05 25.1 0.0 2.9e-05 24.1 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KFX93449.1 - 0.001 19.0 0.1 0.0036 17.2 0.1 1.9 1 1 1 2 2 2 1 RsgA GTPase cobW PF02492.19 KFX93449.1 - 0.02 14.5 0.2 0.26 10.9 0.0 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain PduV-EutP PF10662.9 KFX93449.1 - 0.041 13.6 0.4 7 6.4 0.1 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation IF3_C PF00707.22 KFX93450.1 - 4.1e-08 33.1 0.4 8.1e-08 32.1 0.2 1.6 2 0 0 2 2 2 1 Translation initiation factor IF-3, C-terminal domain mIF3 PF14877.6 KFX93450.1 - 7e-05 22.6 0.0 0.00064 19.4 0.0 2.1 1 1 0 1 1 1 1 Mitochondrial translation initiation factor Peptidase_S24 PF00717.23 KFX93451.1 - 5.8e-10 39.0 0.4 9.7e-10 38.3 0.4 1.3 1 0 0 1 1 1 1 Peptidase S24-like Peptidase_S26 PF10502.9 KFX93451.1 - 9.4e-05 22.2 0.0 0.0043 16.8 0.0 2.3 1 1 0 2 2 2 2 Signal peptidase, peptidase S26 Arm PF00514.23 KFX93452.1 - 1.5e-73 240.8 33.7 4.4e-13 48.8 0.1 11.3 11 1 1 12 12 12 9 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 KFX93452.1 - 1.3e-18 67.0 14.9 1.8e-06 28.3 0.3 7.7 6 1 2 8 8 7 5 HEAT-like repeat HEAT_2 PF13646.6 KFX93452.1 - 5.7e-17 61.9 10.2 0.00027 21.3 0.1 7.0 3 1 4 7 7 7 5 HEAT repeats HEAT PF02985.22 KFX93452.1 - 1.5e-15 56.0 16.1 0.052 13.8 0.3 8.9 10 0 0 10 10 9 4 HEAT repeat Adaptin_N PF01602.20 KFX93452.1 - 1.7e-12 46.7 9.2 2.6e-08 32.9 0.5 2.8 1 1 1 2 2 2 2 Adaptin N terminal region Arm_2 PF04826.13 KFX93452.1 - 1.7e-10 40.8 6.8 2e-05 24.2 3.4 2.7 1 1 1 2 2 2 2 Armadillo-like V-ATPase_H_N PF03224.14 KFX93452.1 - 7e-10 38.7 2.8 6.8e-05 22.3 0.5 3.7 2 1 1 3 3 3 2 V-ATPase subunit H KAP PF05804.12 KFX93452.1 - 1.9e-09 36.3 0.6 4.2e-09 35.2 0.3 1.6 1 1 0 1 1 1 1 Kinesin-associated protein (KAP) Cnd1 PF12717.7 KFX93452.1 - 7.1e-06 26.1 9.0 0.019 15.0 0.8 4.9 1 1 4 5 5 5 2 non-SMC mitotic condensation complex subunit 1 DUF3361 PF11841.8 KFX93452.1 - 0.0001 22.3 8.9 1.2 9.1 0.0 4.4 2 1 3 5 5 5 3 Domain of unknown function (DUF3361) V-ATPase_H_C PF11698.8 KFX93452.1 - 0.00012 22.2 3.1 2.3 8.4 0.2 5.1 2 1 4 6 6 6 1 V-ATPase subunit H DUF5578 PF17741.1 KFX93452.1 - 0.00015 21.3 6.9 0.86 9.0 0.0 4.8 1 1 3 5 5 5 2 Family of unknown function (DUF5578) HEAT_PBS PF03130.16 KFX93452.1 - 0.00086 19.8 6.7 2.8 8.9 0.6 6.7 6 0 0 6 6 6 1 PBS lyase HEAT-like repeat IFRD PF05004.13 KFX93452.1 - 0.0014 17.8 6.1 1.8 7.6 0.1 4.3 3 2 1 4 4 4 2 Interferon-related developmental regulator (IFRD) UNC45-central PF11701.8 KFX93452.1 - 0.0054 16.7 2.3 1.5 8.8 0.2 3.2 2 1 0 3 3 3 1 Myosin-binding striated muscle assembly central Vac14_Fab1_bd PF12755.7 KFX93452.1 - 0.044 14.4 0.2 1.2 9.8 0.1 3.3 2 1 1 4 4 4 0 Vacuolar 14 Fab1-binding region RTP1_C1 PF10363.9 KFX93452.1 - 0.2 11.8 5.4 62 3.8 0.0 4.7 3 1 2 5 5 5 0 Required for nuclear transport of RNA pol II C-terminus 1 Vpu PF00558.19 KFX93452.1 - 0.22 11.3 2.0 0.32 10.8 0.5 2.1 2 0 0 2 2 2 0 Vpu protein Atx10homo_assoc PF09759.9 KFX93452.1 - 0.38 10.8 10.1 2.7 8.1 0.2 4.4 3 2 1 5 5 5 0 Spinocerebellar ataxia type 10 protein domain CBS PF00571.28 KFX93453.1 - 3.5e-21 75.4 9.8 3.6e-08 33.7 0.2 4.3 4 0 0 4 4 4 3 CBS domain HAD_2 PF13419.6 KFX93463.1 - 5e-16 59.3 0.0 1.1e-15 58.2 0.0 1.6 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KFX93463.1 - 1.3e-08 35.4 0.0 1.1e-06 29.2 0.0 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KFX93463.1 - 0.0015 18.6 0.0 0.003 17.6 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like NT5C PF06941.12 KFX93463.1 - 0.033 14.1 0.0 0.28 11.0 0.0 2.0 1 1 0 1 1 1 0 5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C) TPR_14 PF13428.6 KFX93464.1 - 0.0018 19.0 0.9 0.011 16.5 0.1 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_11 PF13414.6 KFX93464.1 - 0.011 15.4 1.8 0.023 14.4 1.8 1.5 1 0 0 1 1 1 0 TPR repeat TPR_12 PF13424.6 KFX93464.1 - 0.015 15.6 0.6 3.5 8.0 0.1 2.5 1 1 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.17 KFX93464.1 - 0.018 15.1 2.8 0.11 12.6 0.8 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_19 PF14559.6 KFX93464.1 - 0.026 15.0 0.1 0.071 13.6 0.1 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_1 PF00515.28 KFX93464.1 - 0.24 11.3 5.9 0.39 10.6 0.6 3.1 3 1 0 3 3 3 0 Tetratricopeptide repeat Acyltransferase PF01553.21 KFX93465.1 - 1.8e-15 56.7 0.0 4.1e-15 55.6 0.0 1.6 1 0 0 1 1 1 1 Acyltransferase UPF0086 PF01868.16 KFX93466.1 - 1.3e-24 85.9 0.1 1.7e-24 85.5 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function UPF0086 HTH_49 PF18010.1 KFX93467.1 - 0.033 14.1 0.0 0.055 13.3 0.0 1.3 1 0 0 1 1 1 0 Cry35Ab1 HTH C-terminal domain DUF4224 PF13986.6 KFX93467.1 - 0.21 11.5 0.4 0.53 10.2 0.3 1.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4224) NMD3 PF04981.13 KFX93468.1 - 2.9e-79 266.0 1.6 5.1e-79 265.2 1.6 1.4 1 0 0 1 1 1 1 NMD3 family DZR PF12773.7 KFX93468.1 - 6.6 6.8 11.2 1e+03 -0.1 11.2 2.6 1 1 0 1 1 1 0 Double zinc ribbon RRM_1 PF00076.22 KFX93469.1 - 1.9e-09 37.2 0.0 5.3e-07 29.4 0.0 2.7 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) F-box PF00646.33 KFX93471.1 - 6.3e-07 29.1 0.1 1.2e-06 28.2 0.1 1.5 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 KFX93471.1 - 5.5e-06 26.2 0.1 1.5e-05 24.8 0.1 1.8 1 0 0 1 1 1 1 F-box-like F-box_4 PF15966.5 KFX93471.1 - 0.1 12.5 0.0 0.24 11.3 0.0 1.6 1 0 0 1 1 1 0 F-box DUF3328 PF11807.8 KFX93472.1 - 1.2e-23 84.1 0.2 3.8e-23 82.4 0.2 1.8 1 1 0 1 1 1 1 Domain of unknown function (DUF3328) Acetyltransf_1 PF00583.25 KFX93473.1 - 0.013 15.8 0.0 0.024 14.9 0.0 1.6 2 0 0 2 2 2 0 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KFX93473.1 - 0.016 15.6 0.0 0.029 14.8 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain PIG-P PF08510.12 KFX93474.1 - 1.8e-51 173.1 0.4 1.8e-51 173.1 0.4 2.1 2 0 0 2 2 2 1 PIG-P MFS_1 PF07690.16 KFX93474.1 - 4.8e-36 124.4 56.9 4.8e-36 124.4 56.9 3.3 3 1 0 3 3 3 2 Major Facilitator Superfamily Pex14_N PF04695.13 KFX93474.1 - 0.021 15.5 1.2 0.15 12.8 0.8 2.5 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region WSC PF01822.19 KFX93475.1 - 6.9e-41 138.3 19.1 2.7e-20 72.4 9.9 2.8 2 0 0 2 2 2 2 WSC domain ABC2_membrane PF01061.24 KFX93476.1 - 3.1e-86 288.1 59.8 4.9e-45 153.5 18.1 3.9 4 0 0 4 4 4 2 ABC-2 type transporter ABC_tran PF00005.27 KFX93476.1 - 1.1e-39 136.1 0.0 8.6e-19 68.4 0.0 2.5 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.12 KFX93476.1 - 2.8e-35 120.1 10.0 1.4e-30 105.1 0.0 3.4 3 0 0 3 3 2 2 CDR ABC transporter ABC_trans_N PF14510.6 KFX93476.1 - 1.3e-15 57.7 0.0 5.4e-15 55.8 0.0 2.1 1 0 0 1 1 1 1 ABC-transporter N-terminal AAA_33 PF13671.6 KFX93476.1 - 3.6e-06 27.2 0.2 0.0085 16.3 0.0 2.7 2 0 0 2 2 2 2 AAA domain RsgA_GTPase PF03193.16 KFX93476.1 - 1.3e-05 25.1 0.5 0.0029 17.5 0.0 2.4 2 0 0 2 2 2 1 RsgA GTPase AAA_16 PF13191.6 KFX93476.1 - 1.9e-05 25.1 0.4 0.022 15.2 0.1 2.6 2 0 0 2 2 2 2 AAA ATPase domain AAA_25 PF13481.6 KFX93476.1 - 0.00019 21.1 2.2 0.0019 17.8 0.2 2.7 3 0 0 3 3 3 1 AAA domain AAA_29 PF13555.6 KFX93476.1 - 0.0011 18.6 1.4 0.064 13.0 0.2 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain SMC_N PF02463.19 KFX93476.1 - 0.0016 17.9 0.0 0.059 12.8 0.0 2.6 2 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 KFX93476.1 - 0.0024 17.8 0.5 2.8 7.7 0.1 2.9 2 1 1 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_18 PF13238.6 KFX93476.1 - 0.0076 16.8 0.2 0.39 11.2 0.0 2.5 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.23 KFX93476.1 - 0.008 16.2 0.0 6.8 6.8 0.0 2.5 2 0 0 2 2 2 2 50S ribosome-binding GTPase cobW PF02492.19 KFX93476.1 - 0.011 15.3 2.6 0.45 10.1 0.2 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_17 PF13207.6 KFX93476.1 - 0.031 14.7 0.2 1.4 9.3 0.0 2.9 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 KFX93476.1 - 0.063 13.0 0.4 1.6 8.4 0.1 2.5 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 KFX93476.1 - 0.15 12.0 3.2 9.8 6.1 0.6 2.6 2 0 0 2 2 2 0 NACHT domain AAA_22 PF13401.6 KFX93476.1 - 0.2 11.9 4.6 4.3 7.6 0.4 3.3 3 1 0 3 3 2 0 AAA domain DUF1772 PF08592.11 KFX93476.1 - 6.2 7.1 6.5 2.6e+02 1.9 0.0 3.4 1 1 1 2 2 2 0 Domain of unknown function (DUF1772) Striatin PF08232.12 KFX93477.1 - 7.8e-42 143.5 0.6 7.8e-42 143.5 0.6 2.7 2 1 0 2 2 2 1 Striatin family WD40 PF00400.32 KFX93477.1 - 4.7e-26 90.5 17.3 7.9e-05 23.4 0.1 7.5 6 2 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFX93477.1 - 5.5e-06 26.6 0.0 1.3 9.3 0.0 4.9 3 1 2 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain DUF5320 PF17253.2 KFX93477.1 - 0.086 13.9 5.9 0.18 12.9 3.7 2.6 2 0 0 2 2 2 0 Family of unknown function (DUF5320) Pho88 PF10032.9 KFX93478.1 - 3.6e-82 274.0 0.2 4.8e-82 273.6 0.2 1.1 1 0 0 1 1 1 1 Phosphate transport (Pho88) Dpy19 PF10034.9 KFX93478.1 - 0.049 11.8 0.2 0.062 11.5 0.2 1.1 1 0 0 1 1 1 0 Q-cell neuroblast polarisation MOFRL PF05161.13 KFX93480.1 - 0.087 13.0 0.0 0.16 12.2 0.0 1.4 1 0 0 1 1 1 0 MOFRL family MFS_1 PF07690.16 KFX93481.1 - 2.2e-28 99.2 32.3 3.3e-28 98.6 32.3 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_4 PF06779.14 KFX93481.1 - 0.00029 20.3 4.2 0.00029 20.3 4.2 1.8 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB PARP PF00644.20 KFX93482.1 - 4.4e-60 202.6 0.1 1.8e-59 200.6 0.0 2.0 2 0 0 2 2 2 1 Poly(ADP-ribose) polymerase catalytic domain PARP_reg PF02877.14 KFX93482.1 - 3.7e-42 143.7 0.1 6.8e-42 142.8 0.1 1.5 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase, regulatory domain WGR PF05406.15 KFX93482.1 - 4.9e-16 58.6 14.2 1.6e-13 50.5 1.0 3.3 3 0 0 3 3 3 2 WGR domain BRCT PF00533.26 KFX93482.1 - 9.4e-10 38.8 0.0 2.1e-09 37.6 0.0 1.7 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.7 KFX93482.1 - 0.00029 20.7 0.0 0.00054 19.8 0.0 1.4 1 0 0 1 1 1 1 twin BRCT domain BRCT_2 PF16589.5 KFX93482.1 - 0.00039 20.8 0.0 0.00081 19.8 0.0 1.5 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain BRCT_3 PF18428.1 KFX93482.1 - 0.0028 17.7 0.0 0.007 16.4 0.0 1.6 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain LIG3_BRCT PF16759.5 KFX93482.1 - 0.16 12.3 0.3 0.46 10.8 0.3 1.7 1 0 0 1 1 1 0 DNA ligase 3 BRCT domain RNA_pol_Rpc4 PF05132.14 KFX93482.1 - 2 8.8 8.3 0.17 12.3 2.9 1.9 2 0 0 2 2 2 0 RNA polymerase III RPC4 Metallophos PF00149.28 KFX93483.1 - 1e-26 94.7 0.0 3.5e-26 93.0 0.0 2.0 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Pur_ac_phosph_N PF16656.5 KFX93483.1 - 3.4e-15 56.4 0.4 3.4e-15 56.4 0.4 3.5 3 1 0 3 3 3 1 Purple acid Phosphatase, N-terminal domain Metallophos_C PF14008.6 KFX93483.1 - 8.4e-14 52.2 2.8 5e-13 49.7 0.1 3.2 2 0 0 2 2 2 1 Iron/zinc purple acid phosphatase-like protein C p450 PF00067.22 KFX93485.1 - 4.5e-28 98.2 0.0 1e-27 97.0 0.0 1.5 1 1 0 1 1 1 1 Cytochrome P450 Peptidase_S64 PF08192.11 KFX93486.1 - 0.0071 14.9 1.2 0.036 12.6 0.0 2.3 3 0 0 3 3 3 1 Peptidase family S64 Peptidase_S32 PF05579.13 KFX93486.1 - 0.11 11.6 0.0 0.17 11.0 0.0 1.2 1 0 0 1 1 1 0 Equine arteritis virus serine endopeptidase S32 Neogenin_C PF06583.12 KFX93492.1 - 0.65 9.8 4.8 0.14 12.0 1.2 1.6 2 0 0 2 2 2 0 Neogenin C-terminus Ribosomal_L16 PF00252.18 KFX93493.1 - 3.9e-45 153.1 0.1 5.6e-45 152.6 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e FUSC PF04632.12 KFX93494.1 - 0.19 10.2 5.6 0.33 9.4 5.6 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF3919 PF13057.6 KFX93494.1 - 0.51 9.9 3.4 1.2 8.7 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3919) Cyt-b5 PF00173.28 KFX93495.1 - 8.9e-21 73.8 0.1 1e-20 73.7 0.1 1.0 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Ceramidase PF05875.12 KFX93496.1 - 6.1e-92 307.8 6.5 7.5e-92 307.5 6.5 1.0 1 0 0 1 1 1 1 Ceramidase Glyco_transf_64 PF09258.10 KFX93496.1 - 0.14 11.5 0.1 0.25 10.6 0.1 1.3 1 0 0 1 1 1 0 Glycosyl transferase family 64 domain Hydrophobin_2 PF06766.11 KFX93497.1 - 0.015 15.3 7.0 0.057 13.4 7.0 1.9 1 1 0 1 1 1 0 Fungal hydrophobin SIS PF01380.22 KFX93498.1 - 3.8e-14 52.7 0.0 6.6e-14 51.9 0.0 1.4 1 0 0 1 1 1 1 SIS domain SIS_2 PF13580.6 KFX93498.1 - 0.0033 17.4 0.2 0.022 14.8 0.0 2.2 2 1 0 2 2 2 1 SIS domain DUF3670 PF12419.8 KFX93498.1 - 0.045 13.6 0.1 0.098 12.5 0.1 1.5 1 0 0 1 1 1 0 SNF2 Helicase protein DUF2810 PF10928.8 KFX93498.1 - 0.048 13.7 0.0 0.11 12.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2810) Vint PF14623.6 KFX93499.1 - 1.3e-55 187.8 0.0 2.5e-55 186.8 0.0 1.5 1 0 0 1 1 1 1 Hint-domain Vwaint PF14624.6 KFX93499.1 - 1e-19 70.4 0.0 2.1e-19 69.4 0.0 1.5 1 0 0 1 1 1 1 VWA / Hh protein intein-like VWA PF00092.28 KFX93499.1 - 3.2e-18 66.6 0.0 6e-18 65.7 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 KFX93499.1 - 2.5e-14 53.8 0.1 8.7e-14 52.1 0.0 2.0 2 0 0 2 2 2 1 von Willebrand factor type A domain VWA_3 PF13768.6 KFX93499.1 - 4.3e-11 43.0 0.0 2.9e-09 37.1 0.0 2.7 2 1 0 2 2 2 1 von Willebrand factor type A domain VWA_CoxE PF05762.14 KFX93499.1 - 0.02 14.3 0.0 0.066 12.6 0.0 1.8 2 0 0 2 2 2 0 VWA domain containing CoxE-like protein GMC_oxred_N PF00732.19 KFX93500.1 - 9.2e-64 215.6 0.0 1.2e-63 215.3 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KFX93500.1 - 4.3e-30 105.1 0.0 7.3e-30 104.4 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.12 KFX93500.1 - 2.2e-05 23.7 0.1 3.4e-05 23.1 0.1 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_binding_2 PF00890.24 KFX93500.1 - 0.00065 18.9 0.3 0.12 11.5 0.2 2.3 2 0 0 2 2 2 2 FAD binding domain Thi4 PF01946.17 KFX93500.1 - 0.0098 15.1 0.3 0.022 14.0 0.3 1.5 1 0 0 1 1 1 1 Thi4 family Trp_halogenase PF04820.14 KFX93500.1 - 0.048 12.5 0.1 0.069 12.0 0.1 1.2 1 0 0 1 1 1 0 Tryptophan halogenase NAD_binding_8 PF13450.6 KFX93500.1 - 0.077 13.2 0.2 0.2 11.9 0.2 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KFX93500.1 - 0.1 11.8 0.1 0.27 10.4 0.0 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KFX93500.1 - 0.2 11.2 2.0 0.88 9.1 2.0 2.1 1 1 0 1 1 1 0 FAD dependent oxidoreductase Lipase_GDSL_2 PF13472.6 KFX93502.1 - 7.3e-10 39.5 3.0 1e-09 39.0 3.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 KFX93502.1 - 2.9e-06 27.4 1.0 4.1e-06 26.9 1.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase AMP-binding PF00501.28 KFX93503.1 - 3.3e-42 144.6 0.2 3.9e-42 144.3 0.2 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KFX93503.1 - 1.2e-18 67.8 0.2 3.2e-18 66.5 0.1 1.8 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain Metallophos PF00149.28 KFX93514.1 - 3e-18 67.0 0.0 4.7e-18 66.4 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 KFX93514.1 - 5e-05 23.5 0.0 0.00045 20.4 0.0 2.1 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain MBOAT PF03062.19 KFX93515.1 - 2.1e-37 129.3 16.1 5.7e-37 127.9 15.8 1.8 1 1 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family Pex14_N PF04695.13 KFX93515.1 - 0.00055 20.6 0.1 0.067 13.8 0.0 2.4 2 1 0 2 2 2 2 Peroxisomal membrane anchor protein (Pex14p) conserved region Adaptin_N PF01602.20 KFX93516.1 - 3e-144 481.5 0.4 3.5e-144 481.2 0.4 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptinC2 PF02883.20 KFX93516.1 - 3.2e-17 62.9 0.0 7.2e-17 61.7 0.0 1.6 1 0 0 1 1 1 1 Adaptin C-terminal domain Cnd1 PF12717.7 KFX93516.1 - 1.3e-07 31.8 8.1 9.7e-05 22.5 0.0 4.5 3 2 2 5 5 5 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 KFX93516.1 - 2.1e-05 24.8 4.9 0.028 14.8 0.0 4.7 6 0 0 6 6 6 2 HEAT repeats DUF3730 PF12530.8 KFX93516.1 - 3.7e-05 23.4 0.8 0.0015 18.1 0.1 2.8 2 1 1 3 3 3 1 Protein of unknown function (DUF3730) HEAT_EZ PF13513.6 KFX93516.1 - 0.015 15.8 1.3 63 4.2 0.0 5.5 5 2 0 5 5 5 0 HEAT-like repeat HEAT PF02985.22 KFX93516.1 - 0.03 14.6 4.5 6.5 7.3 0.1 4.7 5 0 0 5 5 5 0 HEAT repeat AAA_18 PF13238.6 KFX93517.1 - 4.1e-06 27.4 0.1 1.2e-05 25.9 0.1 1.8 1 1 0 1 1 1 1 AAA domain AAA_28 PF13521.6 KFX93517.1 - 0.0002 21.7 0.0 0.00029 21.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 KFX93517.1 - 0.0012 19.0 0.1 0.0036 17.5 0.1 1.8 1 1 0 1 1 1 1 AAA domain AAA PF00004.29 KFX93517.1 - 0.0015 19.0 0.0 0.0021 18.5 0.0 1.2 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.6 KFX93517.1 - 0.004 16.9 0.6 0.013 15.3 0.5 1.7 1 1 0 1 1 1 1 AAA domain SKI PF01202.22 KFX93517.1 - 0.0043 17.2 0.2 0.019 15.1 0.0 1.9 1 1 0 2 2 2 1 Shikimate kinase ABC_tran PF00005.27 KFX93517.1 - 0.008 16.7 0.0 0.0096 16.4 0.0 1.5 1 1 0 1 1 1 1 ABC transporter DUF2075 PF09848.9 KFX93517.1 - 0.0095 15.2 0.0 0.015 14.5 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) PduV-EutP PF10662.9 KFX93517.1 - 0.026 14.3 0.0 0.037 13.8 0.0 1.2 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_22 PF13401.6 KFX93517.1 - 0.026 14.8 0.0 0.037 14.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.22 KFX93517.1 - 0.033 13.4 0.0 0.042 13.0 0.0 1.3 1 1 0 1 1 1 0 NB-ARC domain Ploopntkinase3 PF18751.1 KFX93517.1 - 0.038 13.9 0.0 0.051 13.5 0.0 1.3 1 0 0 1 1 1 0 P-loop Nucleotide Kinase3 Cytidylate_kin2 PF13189.6 KFX93517.1 - 0.039 14.1 0.0 0.055 13.6 0.0 1.3 1 0 0 1 1 1 0 Cytidylate kinase-like family NACHT PF05729.12 KFX93517.1 - 0.041 13.8 0.7 0.061 13.2 0.2 1.8 2 1 0 2 2 2 0 NACHT domain MMR_HSR1 PF01926.23 KFX93517.1 - 0.044 13.9 0.0 0.065 13.3 0.0 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_17 PF13207.6 KFX93517.1 - 0.051 14.0 0.0 0.68 10.3 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.14 KFX93517.1 - 0.061 13.3 0.0 0.082 12.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Zeta_toxin PF06414.12 KFX93517.1 - 0.071 12.4 0.0 0.099 11.9 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin AAA_25 PF13481.6 KFX93517.1 - 0.074 12.6 0.2 0.12 11.9 0.2 1.4 1 1 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 KFX93517.1 - 0.11 12.9 0.0 0.16 12.4 0.0 1.3 1 0 0 1 1 1 0 RNA helicase AAA_16 PF13191.6 KFX93517.1 - 0.13 12.6 0.0 0.17 12.2 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain RuvB_N PF05496.12 KFX93517.1 - 0.17 11.6 0.0 0.24 11.2 0.0 1.2 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain NTPase_1 PF03266.15 KFX93517.1 - 0.21 11.5 0.0 0.35 10.8 0.0 1.3 1 0 0 1 1 1 0 NTPase PMT_4TMC PF16192.5 KFX93521.1 - 3.4e-33 114.9 2.9 4.1e-33 114.7 2.9 1.1 1 0 0 1 1 1 1 C-terminal four TMM region of protein-O-mannosyltransferase TauD PF02668.16 KFX93522.1 - 2.1e-49 168.7 0.3 3.2e-49 168.2 0.3 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DUF971 PF06155.12 KFX93522.1 - 3.5e-05 24.4 0.0 0.00011 22.8 0.0 1.9 1 0 0 1 1 1 1 Protein of unknown function (DUF971) CsiD PF08943.10 KFX93522.1 - 0.014 14.5 0.1 0.065 12.3 0.0 2.0 2 0 0 2 2 2 0 CsiD 2OG-FeII_Oxy_3 PF13640.6 KFX93522.1 - 0.032 15.1 1.6 0.12 13.3 1.6 2.0 1 1 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily Mito_carr PF00153.27 KFX93523.1 - 7.6e-64 211.7 3.7 1.7e-21 75.9 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 KFX93523.1 - 0.012 14.8 2.0 2 7.5 0.1 3.2 3 1 1 4 4 4 0 Gammaproteobacterial serine protease HicA_toxin PF07927.12 KFX93523.1 - 0.1 12.7 0.1 0.25 11.4 0.1 1.6 1 0 0 1 1 1 0 HicA toxin of bacterial toxin-antitoxin, TFIID_30kDa PF03540.13 KFX93524.1 - 1.5e-25 88.8 0.2 2.2e-25 88.4 0.2 1.2 1 0 0 1 1 1 1 Transcription initiation factor TFIID 23-30kDa subunit FoP_duplication PF13865.6 KFX93524.1 - 4.2 8.0 6.1 1.1 9.9 2.1 2.0 2 0 0 2 2 2 0 C-terminal duplication domain of Friend of PRMT1 DUF962 PF06127.11 KFX93526.1 - 2.5e-24 85.2 0.0 4.3e-24 84.4 0.0 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF962) DUF3270 PF11674.8 KFX93526.1 - 0.097 12.9 0.7 0.26 11.5 0.6 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF3270) SHS2_Rpb7-N PF03876.17 KFX93527.1 - 6.6e-10 39.2 0.0 1.1e-09 38.5 0.0 1.4 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 S1 PF00575.23 KFX93527.1 - 9e-10 38.8 0.0 1.5e-09 38.0 0.0 1.3 1 0 0 1 1 1 1 S1 RNA binding domain RNA_pol_Rbc25 PF08292.12 KFX93527.1 - 0.0021 18.3 0.1 0.004 17.4 0.0 1.4 1 1 0 1 1 1 1 RNA polymerase III subunit Rpc25 GEN1_C PF18380.1 KFX93528.1 - 7e-27 94.4 0.4 1.7e-26 93.1 0.4 1.7 1 0 0 1 1 1 1 Holliday junction resolvase Gen1 C-terminal domain XPG_I PF00867.18 KFX93528.1 - 7.7e-22 77.5 0.0 1.4e-21 76.6 0.0 1.4 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.17 KFX93528.1 - 0.00095 19.6 0.0 0.0022 18.4 0.0 1.6 1 0 0 1 1 1 1 XPG N-terminal domain LPD22 PF18834.1 KFX93528.1 - 0.023 14.9 1.2 1 9.6 0.0 2.6 2 0 0 2 2 2 0 Large polyvalent protein associated domain 22 XPG_I_2 PF12813.7 KFX93528.1 - 0.046 13.2 0.0 0.094 12.2 0.0 1.4 1 0 0 1 1 1 0 XPG domain containing ADH_N PF08240.12 KFX93529.1 - 2.2e-05 24.3 0.0 3.1e-05 23.8 0.0 1.3 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Spt5-NGN PF03439.13 KFX93530.1 - 7.2e-25 86.7 0.1 1.3e-24 85.9 0.1 1.5 1 0 0 1 1 1 1 Early transcription elongation factor of RNA pol II, NGN section Spt5_N PF11942.8 KFX93530.1 - 4.6e-20 72.4 8.8 4.6e-20 72.4 8.8 3.8 3 1 1 4 4 4 1 Spt5 transcription elongation factor, acidic N-terminal CTD PF12815.7 KFX93530.1 - 3.2e-17 62.8 28.6 2.4e-16 60.0 14.1 4.8 2 1 2 4 4 4 2 Spt5 C-terminal nonapeptide repeat binding Spt4 KOW PF00467.29 KFX93530.1 - 1e-09 38.0 12.6 0.00083 19.2 0.1 5.5 6 0 0 6 6 6 2 KOW motif DUF3912 PF13051.6 KFX93530.1 - 0.00014 22.0 0.9 0.0009 19.5 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF3912) Cornifin PF02389.15 KFX93530.1 - 0.059 13.6 1.0 0.13 12.5 1.0 1.5 1 0 0 1 1 1 0 Cornifin (SPRR) family FSH1 PF03959.13 KFX93531.1 - 0.087 12.5 0.0 0.4 10.3 0.0 1.9 2 0 0 2 2 2 0 Serine hydrolase (FSH1) Polysacc_deac_1 PF01522.21 KFX93538.1 - 6.4e-32 110.1 0.0 1.1e-31 109.3 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase Chitin_bind_1 PF00187.19 KFX93538.1 - 5.1e-05 23.7 12.5 0.00016 22.1 12.5 1.9 1 0 0 1 1 1 1 Chitin recognition protein Glyco_hydro_57 PF03065.15 KFX93538.1 - 0.00068 18.9 0.0 0.001 18.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 57 nec1 PF10379.9 KFX93538.1 - 1.7 8.1 5.3 23 4.4 0.0 2.4 2 0 0 2 2 2 0 Virulence protein nec1 CH PF00307.31 KFX93539.1 - 2.2e-46 156.5 0.2 2.7e-22 79.0 0.0 3.0 3 0 0 3 3 3 2 Calponin homology (CH) domain EFhand_Ca_insen PF08726.10 KFX93539.1 - 2.5e-22 78.7 0.3 7.5e-22 77.2 0.1 2.0 2 0 0 2 2 2 1 Ca2+ insensitive EF hand CAMSAP_CH PF11971.8 KFX93539.1 - 2.5e-12 46.4 0.1 5.5e-06 26.1 0.0 2.6 2 0 0 2 2 2 2 CAMSAP CH domain EF-hand_6 PF13405.6 KFX93539.1 - 0.00025 20.7 0.2 0.0023 17.7 0.0 2.8 2 0 0 2 2 2 1 EF-hand domain Spectrin PF00435.21 KFX93539.1 - 0.00073 20.0 3.7 0.21 12.1 0.0 2.8 2 0 0 2 2 2 2 Spectrin repeat EF-hand_1 PF00036.32 KFX93539.1 - 0.014 14.9 0.1 0.2 11.3 0.0 2.7 2 0 0 2 2 2 0 EF hand EF-hand_7 PF13499.6 KFX93539.1 - 0.015 15.8 1.4 0.015 15.8 1.4 2.7 3 0 0 3 3 3 0 EF-hand domain pair EF-hand_8 PF13833.6 KFX93539.1 - 0.023 14.6 0.7 0.23 11.4 0.0 2.8 2 1 1 3 3 3 0 EF-hand domain pair EIAV_Rev PF11129.8 KFX93539.1 - 0.18 12.0 1.5 0.41 10.8 1.5 1.5 1 0 0 1 1 1 0 Rev protein of equine infectious anaemia virus DUF4508 PF14969.6 KFX93539.1 - 0.23 11.8 1.5 8.4 6.7 0.2 3.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4508) RIX1 PF08167.12 KFX93541.1 - 3e-61 206.5 0.3 1e-60 204.8 0.3 2.0 1 0 0 1 1 1 1 rRNA processing/ribosome biogenesis TPR_14 PF13428.6 KFX93542.1 - 0.00093 19.8 8.0 8.8 7.4 0.1 5.9 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_8 PF13181.6 KFX93542.1 - 0.002 18.2 4.6 2.6 8.5 0.1 4.9 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_2 PF07719.17 KFX93542.1 - 0.022 14.8 5.5 46 4.5 0.0 5.5 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_17 PF13431.6 KFX93542.1 - 0.023 15.0 0.0 3.6 8.2 0.0 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.6 KFX93542.1 - 1.9 9.2 7.4 13 6.6 0.1 4.0 6 0 0 6 6 6 0 Tetratricopeptide repeat Ank_2 PF12796.7 KFX93548.1 - 3.5e-53 178.1 12.1 2.4e-15 56.9 0.1 7.3 2 1 5 8 8 8 7 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KFX93548.1 - 2.6e-49 165.0 10.0 3e-08 34.1 0.0 9.4 5 2 5 10 10 10 9 Ankyrin repeats (many copies) Ank PF00023.30 KFX93548.1 - 5e-39 131.1 32.5 0.00012 22.3 0.1 12.4 13 0 0 13 13 12 9 Ankyrin repeat Ank_3 PF13606.6 KFX93548.1 - 3.4e-34 113.0 20.4 0.012 16.1 0.1 13.2 13 0 0 13 13 13 8 Ankyrin repeat Ank_5 PF13857.6 KFX93548.1 - 7.8e-27 93.0 14.3 2.6e-05 24.4 0.2 9.4 4 3 6 10 10 10 8 Ankyrin repeats (many copies) NACHT PF05729.12 KFX93548.1 - 8.7e-06 25.8 0.0 2.4e-05 24.3 0.0 1.8 1 0 0 1 1 1 1 NACHT domain SesA PF17107.5 KFX93548.1 - 0.0013 18.9 1.1 0.017 15.3 0.1 3.3 4 0 0 4 4 4 1 N-terminal domain on NACHT_NTPase and P-loop NTPases AAA PF00004.29 KFX93548.1 - 0.047 14.1 0.0 0.63 10.5 0.0 2.6 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) KAP_NTPase PF07693.14 KFX93548.1 - 0.048 12.9 0.0 0.11 11.8 0.0 1.5 1 0 0 1 1 1 0 KAP family P-loop domain AAA_22 PF13401.6 KFX93548.1 - 0.053 13.8 0.0 0.13 12.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain Helo_like_N PF17111.5 KFX93548.1 - 0.57 9.5 6.5 0.37 10.1 3.5 2.2 2 1 0 2 2 2 0 Fungal N-terminal domain of STAND proteins Ank_3 PF13606.6 KFX93549.1 - 1.5e-11 43.5 1.4 0.028 14.9 0.0 6.8 8 0 0 8 8 8 3 Ankyrin repeat Ank_5 PF13857.6 KFX93549.1 - 1.6e-11 44.2 3.1 2.8e-07 30.7 0.1 4.1 4 1 2 6 6 6 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 KFX93549.1 - 8.5e-11 42.3 0.5 0.00075 20.0 0.1 3.7 1 1 3 4 4 4 3 Ankyrin repeats (3 copies) Acetyltransf_10 PF13673.7 KFX93549.1 - 1.1e-10 41.5 0.0 5.6e-10 39.2 0.0 2.0 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KFX93549.1 - 3.8e-09 36.8 0.0 7.7e-09 35.8 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KFX93549.1 - 6.9e-07 29.6 0.0 1.8e-06 28.2 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Ank PF00023.30 KFX93549.1 - 1e-05 25.7 3.7 0.017 15.5 0.1 4.9 5 1 0 5 5 5 1 Ankyrin repeat Ank_4 PF13637.6 KFX93549.1 - 1.8e-05 25.2 5.1 0.32 11.6 0.1 5.6 3 1 4 7 7 7 1 Ankyrin repeats (many copies) Acetyltransf_9 PF13527.7 KFX93549.1 - 0.068 13.2 0.0 0.13 12.4 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 KFX93549.1 - 0.095 12.8 0.0 0.21 11.8 0.0 1.5 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase GDC-P PF02347.16 KFX93550.1 - 2e-179 596.9 0.0 2e-169 564.0 0.0 2.7 2 1 0 2 2 2 2 Glycine cleavage system P-protein Beta_elim_lyase PF01212.21 KFX93550.1 - 6.8e-06 25.6 0.1 1.3e-05 24.7 0.1 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.17 KFX93550.1 - 0.049 12.9 0.0 0.085 12.2 0.0 1.3 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family YadA_stalk PF05662.14 KFX93552.1 - 0.054 13.9 7.6 1.5 9.2 0.1 3.5 4 0 0 4 4 4 0 Coiled stalk of trimeric autotransporter adhesin KIP1 PF07765.12 KFX93552.1 - 0.079 13.1 0.0 20 5.4 0.0 2.4 2 0 0 2 2 2 0 KIP1-like protein Syntaxin PF00804.25 KFX93552.1 - 0.37 10.4 1.5 1.3 8.7 0.5 1.8 1 1 1 2 2 2 0 Syntaxin CLPTM1 PF05602.12 KFX93553.1 - 8.9e-153 509.3 0.0 1.1e-152 509.1 0.0 1.1 1 0 0 1 1 1 1 Cleft lip and palate transmembrane protein 1 (CLPTM1) 2TM PF13239.6 KFX93553.1 - 1.9 8.8 4.4 3.4 8.0 0.2 2.8 2 0 0 2 2 2 0 2TM domain Lysine_decarbox PF03641.14 KFX93554.1 - 1.5e-29 102.8 0.0 2.1e-29 102.3 0.0 1.2 1 0 0 1 1 1 1 Possible lysine decarboxylase LDcluster4 PF18306.1 KFX93554.1 - 0.00015 21.4 0.3 0.0087 15.7 0.0 2.6 2 1 1 3 3 3 1 SLOG cluster4 family LSDAT_prok PF18171.1 KFX93554.1 - 0.13 11.5 0.1 0.18 11.0 0.1 1.4 1 0 0 1 1 1 0 SLOG in TRPM, prokaryote Vps55 PF04133.14 KFX93555.1 - 1.1e-45 154.4 7.2 1.2e-45 154.2 7.2 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting 55 Proteasome PF00227.26 KFX93556.1 - 7.9e-47 159.2 0.1 9.7e-47 158.9 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 KFX93556.1 - 7.1e-11 41.6 0.2 1.2e-10 40.8 0.2 1.4 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Chorismate_bind PF00425.18 KFX93557.1 - 9.2e-66 222.0 0.0 2.1e-37 129.1 0.0 2.3 2 0 0 2 2 2 2 chorismate binding enzyme GATase PF00117.28 KFX93557.1 - 2.3e-22 79.7 0.0 1.9e-20 73.5 0.0 2.6 1 1 0 1 1 1 1 Glutamine amidotransferase class-I Anth_synt_I_N PF04715.13 KFX93557.1 - 3.2e-12 46.8 0.0 7.1e-12 45.7 0.0 1.6 2 0 0 2 2 2 1 Anthranilate synthase component I, N terminal region Peptidase_C26 PF07722.13 KFX93557.1 - 0.014 15.1 1.6 0.1 12.3 0.1 2.1 2 0 0 2 2 2 0 Peptidase C26 EamA PF00892.20 KFX93558.1 - 1.8e-05 24.9 30.7 0.00019 21.6 11.0 2.2 2 0 0 2 2 2 2 EamA-like transporter family Thioredoxin PF00085.20 KFX93559.1 - 1.5e-06 28.1 0.0 2.8e-06 27.3 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin Phosducin PF02114.16 KFX93559.1 - 1.5e-05 24.1 0.1 1.8e-05 23.8 0.1 1.1 1 0 0 1 1 1 1 Phosducin Mt_ATP-synt_B PF05405.14 KFX93559.1 - 0.086 12.5 0.1 0.14 11.8 0.1 1.3 1 0 0 1 1 1 0 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) ARD PF03079.14 KFX93560.1 - 3.1e-43 147.7 0.1 3.1e-43 147.7 0.1 1.6 2 0 0 2 2 2 1 ARD/ARD' family adh_short PF00106.25 KFX93560.1 - 6e-29 100.9 0.0 9.2e-29 100.3 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KFX93560.1 - 2.9e-19 69.6 0.0 4.6e-19 68.9 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Cupin_2 PF07883.11 KFX93560.1 - 3.4e-08 33.1 0.0 7.9e-08 31.9 0.0 1.5 1 0 0 1 1 1 1 Cupin domain KR PF08659.10 KFX93560.1 - 3.6e-07 30.3 0.0 8.2e-07 29.1 0.0 1.5 1 0 0 1 1 1 1 KR domain AraC_binding PF02311.19 KFX93560.1 - 2.3e-05 24.3 0.0 4.8e-05 23.3 0.0 1.5 1 0 0 1 1 1 1 AraC-like ligand binding domain Epimerase PF01370.21 KFX93560.1 - 4.6e-05 23.0 0.1 0.00012 21.6 0.1 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GIDA PF01134.22 KFX93561.1 - 4.1e-159 529.9 0.0 5.9e-159 529.3 0.0 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A GIDA_assoc PF13932.6 KFX93561.1 - 2.1e-65 220.8 0.0 3.1e-65 220.3 0.0 1.2 1 0 0 1 1 1 1 GidA associated domain FAD_oxidored PF12831.7 KFX93561.1 - 1.1e-06 28.3 0.2 2e-06 27.4 0.2 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KFX93561.1 - 1.2e-05 24.7 0.4 4.5e-05 22.8 0.4 1.8 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KFX93561.1 - 0.0006 19.0 1.7 0.0011 18.2 1.7 1.4 1 0 0 1 1 1 1 FAD binding domain AlaDh_PNT_C PF01262.21 KFX93561.1 - 0.0082 15.5 0.0 0.018 14.4 0.0 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain HI0933_like PF03486.14 KFX93561.1 - 0.014 14.1 1.5 0.097 11.4 0.5 2.4 2 0 0 2 2 2 0 HI0933-like protein Pet127 PF08634.10 KFX93562.1 - 2.1e-116 388.2 0.1 2.8e-116 387.7 0.1 1.2 1 0 0 1 1 1 1 Mitochondrial protein Pet127 POP1 PF06978.11 KFX93562.1 - 6.3e-20 72.0 9.4 6.3e-20 72.0 9.4 2.6 2 1 0 2 2 2 1 Ribonucleases P/MRP protein subunit POP1 CHASE2 PF05226.11 KFX93563.1 - 0.086 12.5 0.2 0.1 12.3 0.2 1.2 1 0 0 1 1 1 0 CHASE2 domain TT_ORF2 PF02957.15 KFX93563.1 - 0.22 12.5 1.5 0.55 11.2 1.5 1.6 1 0 0 1 1 1 0 TT viral ORF2 Mst1_SARAH PF11629.8 KFX93563.1 - 1.9 8.6 7.7 0.62 10.2 3.9 2.3 2 0 0 2 2 2 0 C terminal SARAH domain of Mst1 zf-MYND PF01753.18 KFX93564.1 - 5.9e-11 42.3 11.5 1.2e-10 41.3 11.5 1.5 1 0 0 1 1 1 1 MYND finger zf-C6H2 PF15801.5 KFX93564.1 - 0.044 14.1 12.3 0.044 14.1 12.3 2.2 2 1 0 2 2 2 0 zf-MYND-like zinc finger, mRNA-binding zf-C2HC5 PF06221.13 KFX93564.1 - 0.13 12.3 5.8 0.23 11.5 5.8 1.3 1 0 0 1 1 1 0 Putative zinc finger motif, C2HC5-type UDG PF03167.19 KFX93567.1 - 7.2e-19 68.3 0.0 1.5e-18 67.2 0.0 1.6 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily UDPGP PF01704.18 KFX93568.1 - 2.3e-54 184.6 0.0 2.8e-54 184.3 0.0 1.1 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase NTP_transf_3 PF12804.7 KFX93568.1 - 0.066 13.6 0.1 0.17 12.3 0.1 1.7 1 0 0 1 1 1 0 MobA-like NTP transferase domain APH PF01636.23 KFX93569.1 - 2.2e-12 47.4 0.0 1.3e-11 44.9 0.0 2.2 2 1 0 2 2 2 1 Phosphotransferase enzyme family EcKinase PF02958.20 KFX93569.1 - 0.0056 16.0 0.0 0.0095 15.3 0.0 1.3 1 0 0 1 1 1 1 Ecdysteroid kinase adh_short_C2 PF13561.6 KFX93570.1 - 1.6e-54 185.0 2.3 1.8e-54 184.7 2.3 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KFX93570.1 - 8.6e-49 165.6 0.2 1.1e-48 165.4 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KFX93570.1 - 1.1e-12 48.3 0.2 1.4e-12 47.9 0.2 1.1 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 KFX93570.1 - 0.00039 19.6 0.0 0.00049 19.3 0.0 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Epimerase PF01370.21 KFX93570.1 - 0.016 14.7 0.1 0.17 11.3 0.1 2.0 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family ADH_zinc_N PF00107.26 KFX93570.1 - 0.13 12.2 1.1 11 6.0 0.0 2.7 2 1 0 3 3 3 0 Zinc-binding dehydrogenase E1-N PF14463.6 KFX93570.1 - 0.19 11.6 4.0 0.98 9.2 0.1 2.7 3 0 0 3 3 3 0 E1 N-terminal domain adh_short_C2 PF13561.6 KFX93571.1 - 3.8e-11 43.0 0.1 8.4e-11 41.9 0.2 1.6 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KFX93571.1 - 4.1e-11 42.7 0.0 5.7e-11 42.2 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase 2-Hacid_dh_C PF02826.19 KFX93571.1 - 0.014 14.8 0.0 0.023 14.1 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 3HCDH_N PF02737.18 KFX93571.1 - 0.015 15.2 0.0 0.022 14.6 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_10 PF13460.6 KFX93571.1 - 0.027 14.3 0.0 0.051 13.5 0.0 1.5 1 1 0 1 1 1 0 NAD(P)H-binding NmrA PF05368.13 KFX93571.1 - 0.029 13.9 0.1 0.18 11.3 0.0 2.2 2 1 0 2 2 2 0 NmrA-like family Shikimate_DH PF01488.20 KFX93571.1 - 0.056 13.5 0.0 0.086 12.9 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase RIC3 PF15361.6 KFX93572.1 - 0.0029 18.0 0.0 0.0032 17.9 0.0 1.3 1 1 0 1 1 1 1 Resistance to inhibitors of cholinesterase homologue 3 ZapB PF06005.12 KFX93572.1 - 0.0099 16.3 1.4 0.011 16.2 0.2 1.6 2 0 0 2 2 2 1 Cell division protein ZapB Zot PF05707.12 KFX93572.1 - 0.038 13.6 0.3 2 8.0 0.2 2.1 1 1 1 2 2 2 0 Zonular occludens toxin (Zot) YabA PF06156.13 KFX93572.1 - 0.098 13.3 0.4 0.16 12.6 0.2 1.5 1 1 0 1 1 1 0 Initiation control protein YabA YscJ_FliF_C PF08345.11 KFX93572.1 - 0.1 12.9 0.5 0.24 11.7 0.1 1.9 1 1 0 1 1 1 0 Flagellar M-ring protein C-terminal zf-CpG_bind_C PF12269.8 KFX93572.1 - 0.14 12.0 0.1 0.16 11.7 0.1 1.2 1 0 0 1 1 1 0 CpG binding protein zinc finger C terminal domain Tho2 PF11262.8 KFX93572.1 - 0.17 11.1 2.0 9.9 5.3 0.0 2.0 1 1 1 2 2 2 0 Transcription factor/nuclear export subunit protein 2 Antimicrobial_8 PF08103.11 KFX93572.1 - 0.22 11.7 1.4 5.2 7.4 0.1 2.8 2 1 1 3 3 3 0 Uperin family Peptidase_S9_N PF02897.15 KFX93573.1 - 0.19 10.5 0.0 0.26 10.0 0.0 1.1 1 0 0 1 1 1 0 Prolyl oligopeptidase, N-terminal beta-propeller domain Glyco_hydro_76 PF03663.14 KFX93576.1 - 2.3e-101 339.9 6.5 2.9e-101 339.6 6.5 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 AT_hook PF02178.19 KFX93578.1 - 0.0014 18.2 12.0 0.96 9.5 8.1 3.1 2 0 0 2 2 2 2 AT hook motif SRI PF08236.11 KFX93580.1 - 6.2e-21 74.4 11.8 1.8e-20 72.9 11.8 1.9 1 0 0 1 1 1 1 SRI (Set2 Rpb1 interacting) domain SET PF00856.28 KFX93580.1 - 2.7e-18 66.9 0.3 2.7e-18 66.9 0.3 3.5 3 2 0 3 3 3 1 SET domain AWS PF17907.1 KFX93580.1 - 1.6e-13 50.4 13.3 1.6e-13 50.4 13.3 2.4 2 0 0 2 2 2 1 AWS domain Med26 PF08711.11 KFX93580.1 - 0.00016 21.6 0.1 0.00059 19.8 0.1 2.0 1 0 0 1 1 1 1 TFIIS helical bundle-like domain WW PF00397.26 KFX93580.1 - 0.005 16.9 1.6 0.014 15.5 1.6 1.8 1 0 0 1 1 1 1 WW domain AA_permease_2 PF13520.6 KFX93581.1 - 3.9e-86 289.5 33.0 5.3e-86 289.1 33.0 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KFX93581.1 - 6.3e-17 61.3 31.5 9.3e-17 60.8 31.5 1.1 1 0 0 1 1 1 1 Amino acid permease adh_short PF00106.25 KFX93597.1 - 1.8e-37 128.7 0.0 3.3e-37 127.8 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KFX93597.1 - 1.2e-24 87.2 0.0 2.1e-24 86.4 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KFX93597.1 - 1.5e-07 31.5 4.0 0.0002 21.3 0.2 2.3 2 0 0 2 2 2 2 KR domain Epimerase PF01370.21 KFX93597.1 - 1.1e-05 25.1 0.0 1.7e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Sugar_tr PF00083.24 KFX93597.1 - 0.00019 20.4 1.9 0.00031 19.7 1.9 1.3 1 0 0 1 1 1 1 Sugar (and other) transporter RmlD_sub_bind PF04321.17 KFX93597.1 - 0.0039 16.3 0.0 0.0061 15.7 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain PGAP1 PF07819.13 KFX93598.1 - 4.9e-92 307.8 0.0 6.5e-92 307.4 0.0 1.1 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_6 PF12697.7 KFX93598.1 - 2e-05 25.3 0.1 4.3e-05 24.2 0.1 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KFX93598.1 - 0.0045 16.3 0.0 0.009 15.3 0.0 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KFX93598.1 - 0.0097 15.6 0.0 0.02 14.5 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Palm_thioest PF02089.15 KFX93598.1 - 0.023 14.5 0.0 0.044 13.6 0.0 1.4 1 0 0 1 1 1 0 Palmitoyl protein thioesterase DUF676 PF05057.14 KFX93598.1 - 0.034 13.6 0.0 0.073 12.6 0.0 1.4 1 0 0 1 1 1 0 Putative serine esterase (DUF676) LCAT PF02450.15 KFX93598.1 - 0.14 11.3 0.0 0.23 10.6 0.0 1.2 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase GnHR_trans PF12369.8 KFX93599.1 - 0.13 13.1 0.6 0.37 11.6 0.1 1.8 2 0 0 2 2 2 0 Gonadotropin hormone receptor transmembrane region p450 PF00067.22 KFX93600.1 - 3.4e-47 161.2 0.0 6.4e-47 160.3 0.0 1.3 1 1 0 1 1 1 1 Cytochrome P450 E1-E2_ATPase PF00122.20 KFX93605.1 - 3.8e-34 117.8 10.8 3.1e-19 69.2 0.0 4.8 3 1 0 4 4 4 3 E1-E2 ATPase Cation_ATPase_C PF00689.21 KFX93605.1 - 4.1e-26 91.8 2.7 4.1e-26 91.8 2.7 2.4 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 KFX93605.1 - 7.1e-19 68.9 0.1 3.5e-18 66.7 0.1 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 KFX93605.1 - 1e-17 63.6 0.0 2.8e-17 62.2 0.0 1.8 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Cation_ATPase PF13246.6 KFX93605.1 - 9.6e-12 44.8 0.0 1.7e-11 44.0 0.0 1.4 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 KFX93605.1 - 3e-05 23.9 2.9 6.6e-05 22.8 1.1 2.0 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 KFX93605.1 - 0.15 12.5 0.0 0.55 10.6 0.0 1.9 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase DUF2463 PF09591.10 KFX93605.1 - 0.25 11.2 3.8 0.081 12.8 0.4 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2463) KRE9 PF05390.11 KFX93607.1 - 1.5e-16 61.0 3.3 1.8e-16 60.7 3.3 1.0 1 0 0 1 1 1 1 Yeast cell wall synthesis protein KRE9/KNH1 Peptidase_M24 PF00557.24 KFX93608.1 - 3.1e-54 183.9 0.0 4e-54 183.5 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.16 KFX93608.1 - 8.4e-24 83.7 0.0 2.3e-23 82.2 0.0 1.7 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain Tup_N PF08581.10 KFX93608.1 - 0.085 13.2 1.2 0.15 12.4 0.2 1.9 2 0 0 2 2 2 0 Tup N-terminal HsbA PF12296.8 KFX93608.1 - 0.12 12.8 0.1 0.3 11.5 0.1 1.6 1 0 0 1 1 1 0 Hydrophobic surface binding protein A PALP PF00291.25 KFX93609.1 - 5.3e-66 223.0 0.2 7e-66 222.6 0.2 1.2 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme CBS PF00571.28 KFX93609.1 - 4.2e-12 46.3 0.0 1.7e-08 34.8 0.0 3.3 4 0 0 4 4 4 2 CBS domain HA2 PF04408.23 KFX93613.1 - 8.1e-14 51.8 0.0 8.1e-14 51.8 0.0 2.4 3 0 0 3 3 3 1 Helicase associated domain (HA2) Helicase_C PF00271.31 KFX93613.1 - 1.4e-13 51.1 0.0 3.8e-13 49.8 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 KFX93613.1 - 7.7e-12 45.3 0.0 1.6e-11 44.3 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase OB_NTP_bind PF07717.16 KFX93613.1 - 4.2e-07 30.2 0.1 1.5e-06 28.5 0.0 2.1 2 0 0 2 2 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold AAA_22 PF13401.6 KFX93613.1 - 6.3e-07 29.7 0.1 2e-06 28.1 0.1 1.9 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.27 KFX93613.1 - 0.0024 18.4 0.1 0.016 15.7 0.0 2.3 2 0 0 2 2 2 1 ABC transporter AAA_29 PF13555.6 KFX93613.1 - 0.0029 17.3 0.0 0.01 15.6 0.0 1.9 1 0 0 1 1 1 1 P-loop containing region of AAA domain ATPase PF06745.13 KFX93613.1 - 0.026 13.9 0.0 0.054 12.8 0.0 1.5 1 0 0 1 1 1 0 KaiC Rad17 PF03215.15 KFX93613.1 - 0.15 12.0 0.0 0.35 10.8 0.0 1.5 1 0 0 1 1 1 0 Rad17 P-loop domain RsgA_GTPase PF03193.16 KFX93613.1 - 0.17 11.8 0.3 0.6 10.0 0.0 2.0 2 0 0 2 2 2 0 RsgA GTPase AAA_23 PF13476.6 KFX93613.1 - 0.4 11.2 8.2 0.79 10.2 0.0 3.5 3 0 0 3 3 3 0 AAA domain Gcn1_N PF12074.8 KFX93614.1 - 6.9e-119 397.3 3.0 6.9e-119 397.3 3.0 3.8 4 0 0 4 4 4 1 Generalcontrol nonderepressible 1 (Gcn1) N-terminal Ribosomal_L19e PF01280.20 KFX93614.1 - 2.4e-59 199.5 6.2 6.8e-59 198.1 6.2 1.9 1 0 0 1 1 1 1 Ribosomal protein L19e HEAT_EZ PF13513.6 KFX93614.1 - 1.9e-31 108.1 27.5 1.3e-06 28.8 0.0 17.4 14 3 5 19 19 18 8 HEAT-like repeat HEAT PF02985.22 KFX93614.1 - 5.4e-29 97.8 22.3 0.25 11.7 0.0 20.0 22 0 0 22 22 20 6 HEAT repeat HEAT_2 PF13646.6 KFX93614.1 - 1.1e-21 76.9 37.9 0.00021 21.6 0.0 14.4 10 4 5 16 16 15 8 HEAT repeats Vac14_Fab1_bd PF12755.7 KFX93614.1 - 1.3e-13 51.4 0.0 3.3 8.4 0.0 10.4 8 2 2 10 10 10 2 Vacuolar 14 Fab1-binding region Cnd1 PF12717.7 KFX93614.1 - 5e-12 46.2 2.7 1.2 9.2 0.1 8.6 6 3 2 10 10 10 4 non-SMC mitotic condensation complex subunit 1 ParcG PF10274.9 KFX93614.1 - 1.3e-10 41.7 3.0 0.0034 17.5 0.0 7.1 9 1 0 9 9 8 2 Parkin co-regulated protein CLASP_N PF12348.8 KFX93614.1 - 3.5e-08 33.3 0.0 0.23 11.0 0.0 5.7 4 1 1 5 5 5 2 CLASP N terminal TIP120 PF08623.10 KFX93614.1 - 5.3e-05 23.1 0.0 0.026 14.3 0.0 5.1 4 2 1 5 5 5 1 TATA-binding protein interacting (TIP20) MMS19_C PF12460.8 KFX93614.1 - 0.00095 18.4 0.2 0.00095 18.4 0.2 7.4 7 1 1 8 8 8 1 RNAPII transcription regulator C-terminal DUF3385 PF11865.8 KFX93614.1 - 0.0014 18.5 0.0 1.2 9.0 0.0 5.1 5 0 0 5 5 5 1 Domain of unknown function (DUF3385) Tti2 PF10521.9 KFX93614.1 - 0.0018 17.9 4.1 0.23 11.0 0.0 5.6 6 0 0 6 6 6 1 Tti2 family Mac-1 PF09028.10 KFX93614.1 - 0.02 14.0 0.1 0.035 13.2 0.1 1.2 1 0 0 1 1 1 0 Mac 1 RTP1_C1 PF10363.9 KFX93614.1 - 0.051 13.7 0.7 86 3.4 0.0 5.3 5 0 0 5 5 4 0 Required for nuclear transport of RNA pol II C-terminus 1 Atypical_Card PF18461.1 KFX93614.1 - 0.15 12.3 0.0 1.4 9.2 0.0 2.7 2 0 0 2 2 2 0 Atypical caspase recruitment domain DUF937 PF06078.11 KFX93614.1 - 0.25 12.0 9.5 6.9 7.3 0.0 5.6 7 1 0 7 7 5 0 Bacterial protein of unknown function (DUF937) U3snoRNP10 PF12397.8 KFX93614.1 - 5.6 7.3 7.6 82 3.6 0.0 5.9 5 1 1 6 6 4 0 U3 small nucleolar RNA-associated protein 10 RIX1 PF08167.12 KFX93614.1 - 6.5 6.4 7.3 1.1 9.0 0.3 3.5 3 0 0 3 3 3 0 rRNA processing/ribosome biogenesis DUF1664 PF07889.12 KFX93615.1 - 0.065 13.3 0.0 0.065 13.3 0.0 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) MscS_porin PF12795.7 KFX93615.1 - 0.096 12.2 0.0 0.11 12.1 0.0 1.1 1 0 0 1 1 1 0 Mechanosensitive ion channel porin domain DUF4192 PF13830.6 KFX93620.1 - 0.0082 16.2 0.1 0.0083 16.2 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4192) LEH PF07858.12 KFX93620.1 - 0.07 13.2 0.1 0.078 13.1 0.1 1.1 1 0 0 1 1 1 0 Limonene-1,2-epoxide hydrolase catalytic domain Parvo_NS1 PF01057.17 KFX93620.1 - 0.073 12.1 0.1 0.082 12.0 0.1 1.0 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 THDPS_N_2 PF14805.6 KFX93620.1 - 0.084 13.1 0.1 0.11 12.7 0.1 1.2 1 0 0 1 1 1 0 Tetrahydrodipicolinate N-succinyltransferase N-terminal TPR_1 PF00515.28 KFX93621.1 - 1.2e-51 170.5 21.1 7.4e-08 31.9 0.1 10.6 10 1 0 10 10 10 9 Tetratricopeptide repeat TPR_2 PF07719.17 KFX93621.1 - 3.6e-45 148.4 18.7 1.8e-05 24.5 0.0 10.5 11 0 0 11 11 10 9 Tetratricopeptide repeat TPR_8 PF13181.6 KFX93621.1 - 1.3e-36 121.7 14.4 2.5e-05 24.2 0.0 10.5 10 1 0 10 10 10 8 Tetratricopeptide repeat TPR_17 PF13431.6 KFX93621.1 - 2.4e-26 90.2 12.6 0.0025 18.1 0.0 9.7 10 0 0 10 10 9 5 Tetratricopeptide repeat TPR_14 PF13428.6 KFX93621.1 - 8.9e-24 82.2 10.4 8.1e-05 23.1 0.0 9.3 5 3 5 10 10 9 6 Tetratricopeptide repeat TPR_16 PF13432.6 KFX93621.1 - 9.5e-22 77.4 12.4 0.00047 20.7 0.0 7.6 5 1 2 8 8 8 6 Tetratricopeptide repeat TPR_19 PF14559.6 KFX93621.1 - 1.4e-21 76.8 18.0 4.9e-05 23.8 0.4 6.5 6 1 1 7 7 6 5 Tetratricopeptide repeat TPR_11 PF13414.6 KFX93621.1 - 1e-20 73.1 28.0 4.7e-06 26.2 0.2 9.5 5 2 5 10 10 10 5 TPR repeat TPR_12 PF13424.6 KFX93621.1 - 1.8e-20 73.0 18.0 6e-05 23.2 0.9 7.5 3 2 5 8 8 8 6 Tetratricopeptide repeat TPR_6 PF13174.6 KFX93621.1 - 8.5e-19 66.9 12.0 0.009 16.6 0.0 9.3 10 0 0 10 10 10 4 Tetratricopeptide repeat TPR_7 PF13176.6 KFX93621.1 - 6.3e-16 57.2 13.8 0.013 15.5 0.1 9.9 9 1 1 10 10 10 4 Tetratricopeptide repeat TPR_9 PF13371.6 KFX93621.1 - 1.6e-14 53.8 9.0 0.0011 19.0 0.1 6.5 2 1 6 8 8 7 6 Tetratricopeptide repeat ANAPC3 PF12895.7 KFX93621.1 - 3.9e-13 49.4 5.2 4.9e-08 33.1 1.8 3.1 3 0 0 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_15 PF13429.6 KFX93621.1 - 3.1e-09 36.5 8.8 0.0028 16.9 0.6 5.5 1 1 1 3 3 3 2 Tetratricopeptide repeat TPR_21 PF09976.9 KFX93621.1 - 1.1e-08 35.1 1.4 0.019 14.6 0.0 4.1 4 2 1 5 5 5 3 Tetratricopeptide repeat-like domain BTAD PF03704.17 KFX93621.1 - 3.5e-07 30.7 1.2 0.17 12.3 0.0 3.6 3 0 0 3 3 3 3 Bacterial transcriptional activator domain TPR_20 PF14561.6 KFX93621.1 - 8e-05 22.9 0.1 1 9.7 0.0 3.9 3 1 1 4 4 3 2 Tetratricopeptide repeat hNIFK_binding PF12196.8 KFX93621.1 - 0.0069 15.8 0.2 0.038 13.5 0.3 2.1 2 0 0 2 2 2 1 FHA Ki67 binding domain of hNIFK ChAPs PF09295.10 KFX93621.1 - 0.013 14.5 1.7 2.3 7.1 0.1 2.8 3 0 0 3 3 3 0 ChAPs (Chs5p-Arf1p-binding proteins) TPR_MalT PF17874.1 KFX93621.1 - 0.021 14.2 2.3 4.2 6.7 0.1 3.1 2 1 1 3 3 3 0 MalT-like TPR region DUF2225 PF09986.9 KFX93621.1 - 0.083 12.6 3.2 0.52 10.0 0.1 2.7 1 1 2 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2225) SNAP PF14938.6 KFX93621.1 - 0.37 10.2 10.4 7.3 5.9 0.0 3.9 1 1 2 4 4 4 0 Soluble NSF attachment protein, SNAP NARP1 PF12569.8 KFX93621.1 - 0.48 9.3 3.3 7.5 5.3 0.0 3.3 2 1 1 3 3 3 0 NMDA receptor-regulated protein 1 TPR_10 PF13374.6 KFX93621.1 - 3.9 7.5 19.8 28 4.7 0.1 7.4 9 0 0 9 9 8 0 Tetratricopeptide repeat Acetyltransf_10 PF13673.7 KFX93623.1 - 6e-06 26.2 0.0 0.026 14.5 0.0 2.2 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KFX93623.1 - 7.5e-06 26.2 0.0 1.3e-05 25.4 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_CG PF14542.6 KFX93623.1 - 1.8e-05 24.8 0.0 3.2e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_7 PF13508.7 KFX93623.1 - 0.00011 22.6 0.0 0.00023 21.5 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_5 PF13444.6 KFX93623.1 - 0.047 14.4 0.0 0.27 12.0 0.0 2.1 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain HSP70 PF00012.20 KFX93624.1 - 9.4e-59 199.1 2.2 9e-57 192.6 0.0 2.7 3 1 0 3 3 3 2 Hsp70 protein Peptidase_M22 PF00814.25 KFX93624.1 - 0.017 14.8 0.2 0.094 12.4 0.0 2.3 3 0 0 3 3 3 0 Glycoprotease family MreB_Mbl PF06723.13 KFX93624.1 - 0.024 13.5 0.0 0.073 11.9 0.0 1.8 2 0 0 2 2 2 0 MreB/Mbl protein TBCA PF02970.16 KFX93624.1 - 0.29 11.5 4.2 0.46 10.8 0.3 3.2 3 0 0 3 3 3 0 Tubulin binding cofactor A Mucin PF01456.17 KFX93624.1 - 6.9 6.7 27.6 3.2 7.7 1.4 3.4 3 0 0 3 3 3 0 Mucin-like glycoprotein Prefoldin_2 PF01920.20 KFX93625.1 - 6.4e-25 87.2 4.2 7.9e-25 86.9 4.2 1.1 1 0 0 1 1 1 1 Prefoldin subunit Spc24 PF08286.11 KFX93625.1 - 0.2 11.9 5.5 3.9 7.8 1.6 2.2 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 FlaC_arch PF05377.11 KFX93625.1 - 0.23 11.9 0.4 0.23 11.9 0.4 2.5 2 1 0 2 2 2 0 Flagella accessory protein C (FlaC) DUF2681 PF10883.8 KFX93626.1 - 0.0066 16.8 0.2 0.008 16.6 0.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2681) SspP PF08179.12 KFX93626.1 - 0.09 13.2 0.4 0.09 13.2 0.4 1.6 2 0 0 2 2 2 0 Small acid-soluble spore protein P family SARAF PF06682.12 KFX93626.1 - 0.17 11.5 0.1 0.18 11.4 0.1 1.0 1 0 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis Vpu PF00558.19 KFX93626.1 - 0.18 11.6 0.0 0.24 11.2 0.0 1.2 1 0 0 1 1 1 0 Vpu protein ANAPC10 PF03256.16 KFX93627.1 - 3.1e-51 173.7 0.0 4.5e-51 173.1 0.0 1.1 1 0 0 1 1 1 1 Anaphase-promoting complex, subunit 10 (APC10) Prothymosin PF03247.14 KFX93627.1 - 1.5 9.3 15.4 3.1 8.3 15.4 1.4 1 0 0 1 1 1 0 Prothymosin/parathymosin family SDA1 PF05285.12 KFX93628.1 - 8.1e-96 321.5 31.7 8.1e-96 321.5 31.7 2.0 2 0 0 2 2 2 1 SDA1 NUC130_3NT PF08158.12 KFX93628.1 - 2.4e-21 75.8 0.0 6.3e-21 74.4 0.0 1.8 1 0 0 1 1 1 1 NUC130/3NT domain Spt20 PF12090.8 KFX93629.1 - 2.9e-46 158.0 0.0 2.9e-46 158.0 0.0 6.6 2 1 2 4 4 4 1 Spt20 family Hexapep PF00132.24 KFX93631.1 - 3.8e-07 29.6 1.9 0.00032 20.3 0.9 3.4 1 1 2 3 3 3 3 Bacterial transferase hexapeptide (six repeats) Fucokinase PF07959.12 KFX93631.1 - 4.6e-05 22.5 1.2 0.038 12.9 0.3 2.1 1 1 1 2 2 2 2 L-fucokinase NTP_transf_3 PF12804.7 KFX93631.1 - 0.0017 18.7 0.0 0.0041 17.5 0.0 1.7 1 0 0 1 1 1 1 MobA-like NTP transferase domain NTP_transferase PF00483.23 KFX93631.1 - 0.0067 16.0 0.0 0.015 14.9 0.0 1.5 1 0 0 1 1 1 1 Nucleotidyl transferase DUF4954 PF16314.5 KFX93631.1 - 0.034 12.3 0.5 0.058 11.5 0.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4954) Hexapep_2 PF14602.6 KFX93631.1 - 0.34 10.7 5.3 7.7 6.4 0.1 2.9 3 1 0 3 3 3 0 Hexapeptide repeat of succinyl-transferase zf-H2C2_2 PF13465.6 KFX93632.1 - 2.4e-05 24.6 2.4 2.4e-05 24.6 2.4 3.1 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 KFX93632.1 - 5.2e-05 23.8 8.5 0.093 13.6 0.2 3.1 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.26 KFX93632.1 - 0.00078 19.8 14.6 0.0044 17.4 4.4 3.3 2 1 0 2 2 2 2 Zinc finger, C2H2 type BTB PF00651.31 KFX93633.1 - 0.00035 20.8 0.1 0.0011 19.2 0.0 1.9 2 0 0 2 2 2 1 BTB/POZ domain NUDIX PF00293.28 KFX93637.1 - 8.5e-17 61.4 1.1 1e-16 61.2 1.1 1.1 1 0 0 1 1 1 1 NUDIX domain NUDIX_2 PF13869.6 KFX93637.1 - 0.0043 16.7 0.0 0.0057 16.2 0.0 1.3 1 0 0 1 1 1 1 Nucleotide hydrolase CFEM PF05730.11 KFX93640.1 - 2.1e-41 139.9 59.4 1.5e-10 41.0 8.9 4.5 4 0 0 4 4 4 4 CFEM domain Esterase_phd PF10503.9 KFX93641.1 - 1.4e-26 93.4 0.2 1.9e-26 93.0 0.2 1.1 1 0 0 1 1 1 1 Esterase PHB depolymerase Peptidase_S9 PF00326.21 KFX93641.1 - 1.4e-07 31.2 0.4 2.4e-07 30.5 0.4 1.5 1 0 0 1 1 1 1 Prolyl oligopeptidase family COesterase PF00135.28 KFX93641.1 - 0.062 12.2 0.3 0.12 11.3 0.3 1.4 1 0 0 1 1 1 0 Carboxylesterase family DUF3429 PF11911.8 KFX93643.1 - 0.00087 19.6 2.0 0.00087 19.6 2.0 1.7 2 1 0 2 2 2 1 Protein of unknown function (DUF3429) SAE2 PF08573.10 KFX93644.1 - 5.3e-37 127.3 0.4 5.3e-37 127.3 0.4 2.5 2 0 0 2 2 2 1 DNA repair protein endonuclease SAE2/CtIP C-terminus FliD_N PF02465.18 KFX93644.1 - 2.6 8.8 6.5 3.7 8.3 0.8 2.9 2 0 0 2 2 2 0 Flagellar hook-associated protein 2 N-terminus Med9 PF07544.13 KFX93644.1 - 6.5 6.9 6.2 1.3 9.2 1.7 2.3 2 0 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 Glyco_hydro_7 PF00840.20 KFX93646.1 - 8.5e-155 515.7 14.5 9.6e-155 515.6 14.5 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 7 p450 PF00067.22 KFX93647.1 - 1.5e-19 70.1 0.0 2.2e-14 53.1 0.0 2.9 1 1 2 3 3 3 3 Cytochrome P450 FAD_binding_4 PF01565.23 KFX93648.1 - 1.4e-19 70.2 2.3 1.8e-19 69.8 1.6 1.6 2 0 0 2 2 2 1 FAD binding domain MccV PF17508.2 KFX93648.1 - 0.19 12.3 0.6 0.76 10.4 0.6 2.1 1 0 0 1 1 1 0 Microcin V bacteriocin FMO-like PF00743.19 KFX93649.1 - 1.2e-16 60.3 0.3 8.3e-16 57.5 0.3 2.1 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.6 KFX93649.1 - 1.8e-11 43.8 0.4 3.6e-08 32.9 0.0 3.1 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.6 KFX93649.1 - 3.4e-09 36.4 0.1 3.8e-08 33.0 0.0 2.5 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KFX93649.1 - 2.8e-08 33.4 0.0 3.1e-05 23.3 0.0 2.5 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KFX93649.1 - 7e-07 29.4 0.0 2.3e-06 27.7 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KFX93649.1 - 2.9e-05 23.8 0.0 0.00075 19.2 0.0 2.4 2 1 0 2 2 2 1 FAD dependent oxidoreductase Shikimate_DH PF01488.20 KFX93649.1 - 0.0001 22.4 0.1 0.06 13.4 0.0 2.5 2 0 0 2 2 2 2 Shikimate / quinate 5-dehydrogenase FAD_binding_2 PF00890.24 KFX93649.1 - 0.015 14.4 0.0 0.023 13.8 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain Thi4 PF01946.17 KFX93649.1 - 0.055 12.7 0.8 0.086 12.1 0.0 1.6 2 0 0 2 2 2 0 Thi4 family NAD_binding_9 PF13454.6 KFX93649.1 - 0.11 12.5 0.0 1 9.4 0.0 2.5 2 0 0 2 2 2 0 FAD-NAD(P)-binding FAD_oxidored PF12831.7 KFX93649.1 - 0.11 11.8 0.0 0.19 11.1 0.0 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase HI0933_like PF03486.14 KFX93649.1 - 0.12 11.1 0.5 0.24 10.1 0.5 1.5 1 0 0 1 1 1 0 HI0933-like protein GPI2 PF06432.11 KFX93650.1 - 2.2e-135 450.6 0.2 2.5e-135 450.3 0.2 1.0 1 0 0 1 1 1 1 Phosphatidylinositol N-acetylglucosaminyltransferase DUF3136 PF11334.8 KFX93650.1 - 0.063 13.1 0.3 0.13 12.1 0.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3136) Annexin PF00191.20 KFX93651.1 - 1.7e-18 66.4 4.0 0.00055 19.9 0.1 4.3 4 0 0 4 4 4 4 Annexin bZIP_1 PF00170.21 KFX93652.1 - 6.1e-06 26.2 6.5 6.1e-06 26.2 6.5 1.8 2 0 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.15 KFX93652.1 - 6.6 6.9 12.1 0.79 9.9 7.6 1.7 2 0 0 2 2 2 0 Basic region leucine zipper Lactonase PF10282.9 KFX93653.1 - 1.1e-06 28.2 0.2 0.00013 21.4 0.0 2.8 1 1 0 2 2 2 1 Lactonase, 7-bladed beta-propeller DUF1815 PF08844.10 KFX93653.1 - 0.16 12.0 0.1 0.3 11.1 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1815) PQQ PF01011.21 KFX93653.1 - 0.2 11.7 1.7 3 7.9 0.1 3.4 4 0 0 4 4 4 0 PQQ enzyme repeat Hemerythrin PF01814.23 KFX93654.1 - 5.3e-11 43.3 0.1 8.3e-11 42.6 0.1 1.4 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain YnfE PF17452.2 KFX93654.1 - 0.029 14.6 0.0 0.05 13.9 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized YnfE-like Pirin PF02678.16 KFX93655.1 - 1e-22 80.1 0.4 2.5e-22 78.9 0.4 1.7 1 0 0 1 1 1 1 Pirin ADH_zinc_N_2 PF13602.6 KFX93655.1 - 5.6e-10 40.4 0.0 1.9e-09 38.6 0.0 1.9 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KFX93655.1 - 2.3e-09 37.1 0.2 9.4e-09 35.1 0.0 2.0 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain Cupin_2 PF07883.11 KFX93655.1 - 1.7e-05 24.5 3.7 5.2e-05 22.9 0.7 3.0 2 1 0 2 2 2 1 Cupin domain RNA_pol_Rpb1_5 PF04998.17 KFX93656.1 - 2.7e-105 351.6 0.1 4.1e-105 351.0 0.1 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_1 PF04997.12 KFX93656.1 - 1.9e-104 349.4 0.0 3e-104 348.7 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_2 PF00623.20 KFX93656.1 - 5.5e-77 257.7 0.0 1e-76 256.8 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_6 PF04992.14 KFX93656.1 - 4.7e-64 215.7 6.3 8.5e-64 214.9 6.3 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 6 RNA_pol_Rpb1_7 PF04990.12 KFX93656.1 - 6.5e-48 162.2 4.1 4.9e-47 159.3 5.2 1.9 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 7 RNA_pol_Rpb1_3 PF04983.18 KFX93656.1 - 6.9e-48 162.5 0.0 1.9e-47 161.1 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.17 KFX93656.1 - 2e-37 127.4 0.1 4.8e-37 126.2 0.1 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 RNA_pol_Rpb1_R PF05001.13 KFX93656.1 - 1.1e-11 44.5 174.4 0.029 14.7 3.1 12.7 9 1 7 16 16 16 14 RNA polymerase Rpb1 C-terminal repeat SelP_N PF04592.14 KFX93659.1 - 1.5 8.1 6.5 2.1 7.7 6.5 1.2 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Pyr_redox_2 PF07992.14 KFX93661.1 - 7.8e-37 127.1 0.0 9.5e-37 126.8 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KFX93661.1 - 6e-15 55.6 0.1 4.2e-11 43.3 0.0 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KFX93661.1 - 9.1e-08 31.7 0.0 3.7e-06 26.4 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KFX93661.1 - 1.9e-07 30.6 0.0 6.8e-05 22.2 0.0 2.1 2 0 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) ApbA PF02558.16 KFX93661.1 - 0.0029 17.2 0.0 0.0056 16.3 0.0 1.5 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA NAD_binding_8 PF13450.6 KFX93661.1 - 0.0041 17.3 0.0 0.91 9.8 0.0 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 KFX93661.1 - 0.0064 15.6 0.0 3.1 6.7 0.0 2.4 2 0 0 2 2 2 2 Lycopene cyclase protein TrkA_N PF02254.18 KFX93661.1 - 0.011 16.0 0.0 3.6 7.9 0.0 2.4 2 0 0 2 2 2 0 TrkA-N domain NAD_binding_9 PF13454.6 KFX93661.1 - 0.024 14.7 0.1 20 5.1 0.0 3.7 4 0 0 4 4 4 0 FAD-NAD(P)-binding DDR PF08841.10 KFX93661.1 - 0.04 12.9 0.0 7.9 5.4 0.0 2.4 2 0 0 2 2 2 0 Diol dehydratase reactivase ATPase-like domain Trp_halogenase PF04820.14 KFX93661.1 - 0.16 10.7 0.8 21 3.8 0.1 2.9 2 1 1 3 3 3 0 Tryptophan halogenase Isochorismatase PF00857.20 KFX93662.1 - 2.6e-14 53.8 0.2 6.8e-14 52.4 0.2 1.7 1 1 0 1 1 1 1 Isochorismatase family Glyco_hydro_43 PF04616.14 KFX93663.1 - 8.9e-30 104.0 3.0 1.4e-29 103.4 3.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 FAD_binding_3 PF01494.19 KFX93663.1 - 2e-22 79.9 0.0 3e-22 79.4 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain GH43_C2 PF17851.1 KFX93663.1 - 5.2e-22 78.6 0.3 8.3e-22 77.9 0.3 1.3 1 0 0 1 1 1 1 Beta xylosidase C-terminal Concanavalin A-like domain Amino_oxidase PF01593.24 KFX93663.1 - 1.3e-05 24.7 0.2 0.0026 17.1 0.1 2.3 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase CBM_1 PF00734.18 KFX93663.1 - 3.2e-05 23.8 8.8 9.2e-05 22.3 8.8 1.8 1 0 0 1 1 1 1 Fungal cellulose binding domain Pyr_redox_3 PF13738.6 KFX93663.1 - 0.00014 21.2 0.0 0.39 9.9 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KFX93663.1 - 0.00023 20.5 0.2 0.4 9.9 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KFX93663.1 - 0.00023 20.4 0.0 0.00046 19.4 0.0 1.4 1 1 0 1 1 1 1 Lycopene cyclase protein NAD_binding_8 PF13450.6 KFX93663.1 - 0.001 19.2 0.0 0.0037 17.4 0.0 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HTH_Tnp_Tc3_2 PF01498.18 KFX93663.1 - 0.047 14.0 0.0 0.12 12.7 0.0 1.6 1 0 0 1 1 1 0 Transposase DAO PF01266.24 KFX93663.1 - 0.44 10.1 2.6 0.73 9.4 0.6 2.4 3 0 0 3 3 3 0 FAD dependent oxidoreductase Pyr_redox PF00070.27 KFX93663.1 - 0.49 11.0 3.5 0.74 10.4 0.2 2.8 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase p450 PF00067.22 KFX93664.1 - 3.3e-56 191.0 0.0 1.7e-34 119.4 0.0 2.0 1 1 1 2 2 2 2 Cytochrome P450 p450 PF00067.22 KFX93665.1 - 2.4e-57 194.7 0.0 3.8e-57 194.1 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 BLM10_mid PF16507.5 KFX93666.1 - 4e-199 662.6 0.0 8.9e-199 661.5 0.0 1.6 2 0 0 2 2 2 1 Proteasome-substrate-size regulator, mid region DUF3437 PF11919.8 KFX93666.1 - 5.8e-29 99.9 0.0 2.5e-28 97.8 0.0 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF3437) BLM10_N PF16547.5 KFX93666.1 - 2.1e-20 72.8 0.0 5.3e-20 71.5 0.0 1.8 1 0 0 1 1 1 1 Proteasome-substrate-size regulator, N-terminal HEAT PF02985.22 KFX93666.1 - 0.051 13.9 0.9 18 6.0 0.1 4.9 5 0 0 5 5 5 0 HEAT repeat Protoglobin PF11563.8 KFX93666.1 - 0.089 12.7 0.0 2.7 7.8 0.0 3.0 3 0 0 3 3 3 0 Protoglobin HEAT_EZ PF13513.6 KFX93666.1 - 0.095 13.2 10.5 6 7.5 0.3 4.9 4 0 0 4 4 4 0 HEAT-like repeat VCBS PF13517.6 KFX93686.1 - 1e-29 102.9 47.3 1.1e-14 54.8 2.6 8.7 3 2 6 9 9 9 8 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella Lipase_GDSL_2 PF13472.6 KFX93686.1 - 1.2e-14 55.2 1.4 3.7e-14 53.5 1.4 1.9 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 KFX93686.1 - 9.1e-09 35.6 0.1 2.1e-08 34.4 0.1 1.7 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase TcdB_toxin_midN PF12256.8 KFX93686.1 - 1.7e-05 24.2 8.8 0.24 10.7 0.1 6.3 5 2 3 8 8 8 2 Insecticide toxin TcdB middle/N-terminal region PliI PF16743.5 KFX93686.1 - 0.02 14.6 0.3 13 5.6 0.0 4.2 5 0 0 5 5 5 0 Periplasmic lysozyme inhibitor of I-type lysozyme Lipase_GDSL_3 PF14606.6 KFX93686.1 - 0.021 15.0 0.0 0.045 13.9 0.0 1.5 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase family Pectate_lyase_3 PF12708.7 KFX93687.1 - 3e-100 334.5 9.2 9.3e-85 283.8 5.3 2.8 2 0 0 2 2 2 2 Pectate lyase superfamily protein End_N_terminal PF12218.8 KFX93687.1 - 1.7e-07 30.8 3.4 0.0041 16.8 0.2 2.6 2 0 0 2 2 2 2 N terminal extension of bacteriophage endosialidase Myb_DNA-bind_4 PF13837.6 KFX93688.1 - 0.023 15.1 1.2 0.052 13.9 0.1 2.2 3 0 0 3 3 3 0 Myb/SANT-like DNA-binding domain Stk19 PF10494.9 KFX93691.1 - 8.8e-38 130.4 0.0 1.1e-37 130.0 0.0 1.1 1 0 0 1 1 1 1 Serine-threonine protein kinase 19 Fe-ADH PF00465.19 KFX93692.1 - 5.9e-75 252.4 0.2 6.8e-75 252.2 0.2 1.0 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.6 KFX93692.1 - 4.3e-12 46.3 0.1 6e-12 45.8 0.1 1.2 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase DUF1677 PF07911.13 KFX93692.1 - 0.21 12.0 0.0 0.44 11.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1677) Meth_synt_2 PF01717.18 KFX93693.1 - 2.7e-08 33.5 0.0 9e-06 25.2 0.0 2.8 2 1 0 2 2 2 2 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.12 KFX93693.1 - 0.029 13.9 0.0 0.21 11.1 0.0 2.0 2 0 0 2 2 2 0 Cobalamin-independent synthase, N-terminal domain Aldolase_II PF00596.21 KFX93694.1 - 2e-39 135.5 1.8 2.7e-39 135.0 1.8 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain Dabb PF07876.12 KFX93695.1 - 1.4e-11 44.8 0.0 1.6e-11 44.7 0.0 1.0 1 0 0 1 1 1 1 Stress responsive A/B Barrel Domain DUF1338 PF07063.13 KFX93696.1 - 2.8e-97 325.8 0.0 3.3e-97 325.6 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1338) Fungal_trans PF04082.18 KFX93697.1 - 6.2e-12 45.1 0.3 1.2e-11 44.1 0.3 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KFX93697.1 - 8.9e-08 32.1 9.9 1.6e-07 31.3 9.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.16 KFX93698.1 - 1.9e-19 69.8 13.4 1.9e-19 69.8 13.4 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily Dioxygenase_C PF00775.21 KFX93699.1 - 5.4e-42 143.3 0.0 7.7e-42 142.8 0.0 1.3 1 0 0 1 1 1 1 Dioxygenase Dioxygenase_N PF04444.14 KFX93699.1 - 6.9e-24 83.5 0.0 1.1e-23 82.9 0.0 1.3 1 0 0 1 1 1 1 Catechol dioxygenase N terminus CarboxypepD_reg PF13620.6 KFX93699.1 - 0.00062 20.0 0.0 0.0015 18.7 0.0 1.6 1 1 0 1 1 1 1 Carboxypeptidase regulatory-like domain ADH_zinc_N PF00107.26 KFX93700.1 - 1.4e-21 76.8 0.2 2.8e-21 75.8 0.2 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KFX93700.1 - 4.7e-10 39.3 1.3 3.8e-09 36.4 0.0 2.9 2 2 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 KFX93700.1 - 2.2e-09 38.5 0.0 5.1e-09 37.3 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase LSM PF01423.22 KFX93702.1 - 1.5e-18 66.2 0.1 1.8e-18 66.0 0.1 1.1 1 0 0 1 1 1 1 LSM domain DUF4403 PF14356.6 KFX93703.1 - 0.0034 16.1 0.2 0.0041 15.8 0.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4403) BNR PF02012.20 KFX93705.1 - 0.046 13.7 0.1 0.096 12.7 0.1 1.6 1 0 0 1 1 1 0 BNR/Asp-box repeat p450 PF00067.22 KFX93706.1 - 3.9e-67 227.0 0.0 5.4e-67 226.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Zn_clus PF00172.18 KFX93707.1 - 2.8e-08 33.7 5.5 6e-08 32.7 5.5 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain p450 PF00067.22 KFX93708.1 - 3.3e-46 158.0 0.0 6.5e-46 157.0 0.0 1.3 1 1 0 1 1 1 1 Cytochrome P450 DUF1999 PF09390.10 KFX93708.1 - 0.11 12.2 0.0 0.2 11.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1999) adh_short PF00106.25 KFX93709.1 - 2.7e-26 92.2 0.1 1.4e-25 89.9 0.1 1.9 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KFX93709.1 - 7e-18 65.0 0.0 3.7e-17 62.7 0.0 1.8 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 KFX93709.1 - 0.0052 16.3 0.0 0.017 14.6 0.0 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.10 KFX93709.1 - 0.014 15.4 0.2 0.061 13.2 0.1 2.3 1 1 0 1 1 1 0 KR domain GDP_Man_Dehyd PF16363.5 KFX93709.1 - 0.17 11.3 0.0 0.31 10.4 0.0 1.4 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase MFS_1 PF07690.16 KFX93710.1 - 6.3e-40 137.2 54.4 6.3e-40 137.2 54.4 2.3 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 KFX93710.1 - 2.1e-13 49.6 28.3 2.9e-13 49.1 28.3 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Transferase PF02458.15 KFX93711.1 - 9.5e-19 67.4 0.0 2.6e-17 62.6 0.0 3.0 2 1 0 2 2 2 1 Transferase family Proteasome PF00227.26 KFX93713.1 - 8.9e-17 61.2 0.0 1.1e-16 60.9 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit eIF3_subunit PF08597.10 KFX93714.1 - 2.2e-72 243.9 22.1 2.5e-72 243.7 22.1 1.0 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit DUF3708 PF12501.8 KFX93714.1 - 2.5 7.8 4.5 1.9 8.3 0.2 2.2 2 0 0 2 2 2 0 Phosphate ATP-binding cassette transporter Erythro_esteras PF05139.14 KFX93716.1 - 2.6e-119 399.1 3.7 3e-119 398.9 3.7 1.0 1 0 0 1 1 1 1 Erythromycin esterase DUF1416 PF07210.12 KFX93716.1 - 0.18 11.7 0.0 7.6 6.5 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1416) ABC_membrane PF00664.23 KFX93717.1 - 8.5e-78 261.8 19.2 4.2e-48 164.4 6.8 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 KFX93717.1 - 1.4e-63 213.5 0.1 4.3e-34 118.0 0.1 3.0 2 1 0 2 2 2 2 ABC transporter Exo_endo_phos PF03372.23 KFX93717.1 - 3.8e-19 69.1 0.1 1.1e-18 67.6 0.1 1.8 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family SMC_N PF02463.19 KFX93717.1 - 6.3e-15 55.2 2.9 0.00019 20.9 0.2 4.3 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 KFX93717.1 - 1.9e-08 34.9 0.5 0.0016 18.9 0.0 2.9 2 1 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.6 KFX93717.1 - 2.4e-08 34.4 0.5 0.01 16.1 0.0 3.7 4 1 0 4 4 3 2 AAA domain RsgA_GTPase PF03193.16 KFX93717.1 - 1.1e-07 31.9 0.0 0.007 16.3 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase AAA_29 PF13555.6 KFX93717.1 - 1.3e-07 31.3 1.0 0.011 15.5 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain LRR_8 PF13855.6 KFX93717.1 - 3e-07 30.1 0.5 3.3e-06 26.8 0.1 2.3 2 0 0 2 2 2 1 Leucine rich repeat AAA_30 PF13604.6 KFX93717.1 - 1.1e-06 28.5 0.5 0.019 14.7 0.0 3.1 3 1 0 3 3 2 2 AAA domain ABC_ATPase PF09818.9 KFX93717.1 - 1.8e-06 27.0 2.7 0.013 14.3 0.0 4.9 5 0 0 5 5 5 1 Predicted ATPase of the ABC class AAA_23 PF13476.6 KFX93717.1 - 2.4e-06 28.2 0.0 0.017 15.6 0.0 2.6 2 0 0 2 2 2 2 AAA domain LRR_4 PF12799.7 KFX93717.1 - 1.3e-05 25.5 4.4 0.0013 19.1 0.4 2.3 1 1 2 3 3 3 2 Leucine Rich repeats (2 copies) AAA_15 PF13175.6 KFX93717.1 - 1.7e-05 24.7 0.0 0.058 13.1 0.0 2.3 2 0 0 2 2 2 2 AAA ATPase domain AAA_21 PF13304.6 KFX93717.1 - 3.2e-05 23.9 0.0 0.16 11.7 0.0 2.9 2 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system Rad17 PF03215.15 KFX93717.1 - 0.00011 22.2 0.0 0.052 13.5 0.0 2.4 2 0 0 2 2 2 1 Rad17 P-loop domain AAA_7 PF12775.7 KFX93717.1 - 0.00017 21.1 0.0 0.25 10.9 0.0 2.4 2 0 0 2 2 2 2 P-loop containing dynein motor region AAA_17 PF13207.6 KFX93717.1 - 0.00045 20.7 0.2 0.1 13.0 0.1 2.8 2 0 0 2 2 2 1 AAA domain AAA PF00004.29 KFX93717.1 - 0.00055 20.4 2.1 0.26 11.7 0.1 4.0 3 1 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 KFX93717.1 - 0.00075 20.1 0.1 1.2 9.6 0.0 2.9 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.14 KFX93717.1 - 0.00085 19.3 0.3 1.1 9.2 0.0 3.5 4 0 0 4 4 3 1 AAA domain (dynein-related subfamily) AAA_25 PF13481.6 KFX93717.1 - 0.00088 18.9 2.9 0.62 9.6 0.0 3.3 4 0 0 4 4 3 2 AAA domain Zeta_toxin PF06414.12 KFX93717.1 - 0.00096 18.5 0.0 0.065 12.5 0.0 2.9 3 0 0 3 3 3 1 Zeta toxin AAA_33 PF13671.6 KFX93717.1 - 0.0042 17.2 0.4 4.8 7.4 0.1 2.7 2 0 0 2 2 2 0 AAA domain PRK PF00485.18 KFX93717.1 - 0.0056 16.4 0.0 2.7 7.7 0.0 2.6 2 0 0 2 2 2 1 Phosphoribulokinase / Uridine kinase family AAA_28 PF13521.6 KFX93717.1 - 0.0064 16.7 0.1 2 8.7 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_24 PF13479.6 KFX93717.1 - 0.018 14.8 0.1 5.3 6.7 0.0 2.7 2 0 0 2 2 2 0 AAA domain ATP_bind_1 PF03029.17 KFX93717.1 - 0.021 14.6 0.1 4.4 7.0 0.0 2.5 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein ATP-synt_ab PF00006.25 KFX93717.1 - 0.022 14.4 0.0 4 7.0 0.0 2.8 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain SbcCD_C PF13558.6 KFX93717.1 - 0.027 14.7 0.8 5.6 7.3 0.1 3.6 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_14 PF13173.6 KFX93717.1 - 0.027 14.5 0.0 1.7 8.7 0.0 3.1 3 0 0 3 3 2 0 AAA domain DUF87 PF01935.17 KFX93717.1 - 0.033 14.3 0.6 2.9 7.9 0.0 3.2 3 0 0 3 3 3 0 Helicase HerA, central domain Cytidylate_kin PF02224.18 KFX93717.1 - 0.039 13.7 0.1 5.9 6.6 0.0 2.5 2 0 0 2 2 2 0 Cytidylate kinase RNA_helicase PF00910.22 KFX93717.1 - 0.046 14.1 0.1 6.2 7.3 0.0 2.7 2 0 0 2 2 2 0 RNA helicase NB-ARC PF00931.22 KFX93717.1 - 0.053 12.7 0.2 1.5 7.9 0.0 2.4 2 0 0 2 2 2 0 NB-ARC domain MMR_HSR1 PF01926.23 KFX93717.1 - 0.073 13.2 0.0 7.1 6.7 0.0 2.9 2 0 0 2 2 2 0 50S ribosome-binding GTPase APS_kinase PF01583.20 KFX93717.1 - 0.09 12.7 0.1 2.5 7.9 0.0 2.5 2 0 0 2 2 2 0 Adenylylsulphate kinase IstB_IS21 PF01695.17 KFX93717.1 - 0.12 12.1 0.1 9.4 5.9 0.0 3.1 3 0 0 3 3 3 0 IstB-like ATP binding protein G-alpha PF00503.20 KFX93717.1 - 0.21 10.7 1.1 5.9 5.9 0.0 2.7 3 0 0 3 3 3 0 G-protein alpha subunit LRR_1 PF00560.33 KFX93717.1 - 0.24 12.1 0.5 16 6.5 0.1 3.3 3 0 0 3 3 2 0 Leucine Rich Repeat Methyltransf_25 PF13649.6 KFX93719.1 - 2.4e-15 57.0 0.0 5e-15 56.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KFX93719.1 - 3.2e-11 43.7 0.0 6.8e-11 42.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KFX93719.1 - 9.3e-10 38.5 0.0 1.6e-09 37.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KFX93719.1 - 4e-07 30.0 0.0 7.8e-07 29.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KFX93719.1 - 3.9e-06 27.5 0.0 8.2e-06 26.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.6 KFX93719.1 - 0.0035 17.3 0.1 0.0098 15.9 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.14 KFX93719.1 - 0.0047 16.5 0.0 0.0089 15.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_24 PF13578.6 KFX93719.1 - 0.0057 17.7 0.0 0.016 16.2 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain MetW PF07021.12 KFX93719.1 - 0.0066 16.1 0.0 0.011 15.3 0.0 1.3 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW PCMT PF01135.19 KFX93719.1 - 0.0072 16.1 0.0 0.028 14.2 0.0 1.8 1 1 1 2 2 2 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) FtsJ PF01728.19 KFX93719.1 - 0.061 13.4 0.0 0.1 12.7 0.0 1.3 1 0 0 1 1 1 0 FtsJ-like methyltransferase Complex1_LYR_2 PF13233.6 KFX93720.1 - 5.1e-05 23.9 0.0 6.2e-05 23.7 0.0 1.1 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.15 KFX93720.1 - 0.00046 20.2 0.0 0.0006 19.8 0.0 1.2 1 0 0 1 1 1 1 Complex 1 protein (LYR family) 4HBT_2 PF13279.6 KFX93721.1 - 1.2e-24 87.1 0.0 2.5e-24 86.1 0.0 1.5 1 0 0 1 1 1 1 Thioesterase-like superfamily 4HBT PF03061.22 KFX93721.1 - 0.014 15.7 0.0 0.025 14.9 0.0 1.5 1 0 0 1 1 1 0 Thioesterase superfamily Acyl-ACP_TE PF01643.17 KFX93721.1 - 0.12 11.6 0.0 4 6.7 0.0 2.5 3 0 0 3 3 3 0 Acyl-ACP thioesterase DUF349 PF03993.12 KFX93721.1 - 2 8.8 5.0 1.5 9.2 2.5 1.9 2 0 0 2 2 2 0 Domain of Unknown Function (DUF349) Pkinase_fungal PF17667.1 KFX93743.1 - 8.9e-108 360.7 0.0 1.1e-107 360.3 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Pkinase PF00069.25 KFX93743.1 - 0.0062 15.9 0.0 0.0096 15.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain RIO1 PF01163.22 KFX93743.1 - 0.047 13.3 0.0 0.077 12.6 0.0 1.3 1 0 0 1 1 1 0 RIO1 family Pkinase PF00069.25 KFX93744.1 - 1.9e-10 40.5 0.0 2.7e-10 40.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.14 KFX93744.1 - 8.8e-05 22.0 0.0 0.00014 21.3 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_Tyr PF07714.17 KFX93744.1 - 0.0005 19.4 0.0 0.00063 19.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KFX93744.1 - 0.0016 18.4 0.2 0.006 16.5 0.2 1.8 1 1 1 2 2 2 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 KFX93744.1 - 0.0075 15.1 0.1 0.011 14.6 0.1 1.1 1 0 0 1 1 1 1 Fungal protein kinase RIO1 PF01163.22 KFX93744.1 - 0.078 12.6 0.3 0.15 11.6 0.0 1.6 2 0 0 2 2 2 0 RIO1 family EcKinase PF02958.20 KFX93744.1 - 0.18 11.1 0.0 0.24 10.6 0.0 1.3 1 0 0 1 1 1 0 Ecdysteroid kinase Mog1 PF04603.12 KFX93745.1 - 0.1 13.0 0.1 0.17 12.3 0.1 1.3 1 0 0 1 1 1 0 Ran-interacting Mog1 protein NmrA PF05368.13 KFX93746.1 - 7.6e-23 81.3 0.1 9.3e-23 81.0 0.1 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KFX93746.1 - 8.9e-15 55.1 0.0 1.6e-14 54.2 0.0 1.5 1 1 0 1 1 1 1 NAD(P)H-binding Shikimate_DH PF01488.20 KFX93746.1 - 0.066 13.3 0.0 0.24 11.5 0.0 1.8 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase DapB_N PF01113.20 KFX93746.1 - 0.1 12.7 0.0 0.27 11.4 0.0 1.7 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Gly_transf_sug PF04488.15 KFX93747.1 - 3.7e-14 53.1 0.0 7.7e-14 52.1 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif IMS PF00817.20 KFX93749.1 - 4e-41 140.5 0.0 6.7e-41 139.8 0.0 1.4 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.8 KFX93749.1 - 6.1e-13 49.5 0.0 1.8e-12 48.0 0.0 1.8 2 0 0 2 2 2 1 impB/mucB/samB family C-terminal domain zf_UBZ PF18439.1 KFX93749.1 - 9.9e-13 47.4 2.2 2.1e-12 46.4 2.2 1.6 1 0 0 1 1 1 1 Ubiquitin-Binding Zinc Finger IMS_HHH PF11798.8 KFX93749.1 - 0.0052 17.0 0.0 0.012 15.9 0.0 1.6 1 0 0 1 1 1 1 IMS family HHH motif zf-C2H2_4 PF13894.6 KFX93749.1 - 0.12 13.3 0.9 0.4 11.7 0.9 2.0 1 0 0 1 1 1 0 C2H2-type zinc finger F-box-like PF12937.7 KFX93750.1 - 0.00037 20.3 0.0 0.00088 19.1 0.0 1.7 1 0 0 1 1 1 1 F-box-like Fungal_lectin PF07938.12 KFX93751.1 - 2.8e-110 368.4 3.7 3.1e-110 368.3 3.7 1.0 1 0 0 1 1 1 1 Fungal fucose-specific lectin PP-binding PF00550.25 KFX93756.1 - 3.4e-11 43.3 0.1 4.4e-11 43.0 0.1 1.2 1 0 0 1 1 1 1 Phosphopantetheine attachment site PP-binding_2 PF14573.6 KFX93756.1 - 5.6e-07 29.7 0.1 7.3e-07 29.3 0.1 1.1 1 0 0 1 1 1 1 Acyl-carrier GPP34 PF05719.11 KFX93757.1 - 2.8e-68 230.0 0.1 3.6e-68 229.6 0.1 1.1 1 0 0 1 1 1 1 Golgi phosphoprotein 3 (GPP34) SURF6 PF04935.12 KFX93758.1 - 4.1e-46 157.3 18.6 5.3e-46 156.9 18.6 1.1 1 0 0 1 1 1 1 Surfeit locus protein 6 HSP70 PF00012.20 KFX93803.1 - 0.013 13.7 0.0 0.023 12.9 0.0 1.3 1 0 0 1 1 1 0 Hsp70 protein Pectinesterase PF01095.19 KFX93804.1 - 3.5e-46 157.3 6.8 4.4e-46 156.9 6.8 1.1 1 0 0 1 1 1 1 Pectinesterase Glyco_hydro_28 PF00295.17 KFX93805.1 - 9.7e-46 156.3 10.2 1.2e-45 156.0 10.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 Beta_helix PF13229.6 KFX93805.1 - 3.4e-05 23.8 11.3 0.00045 20.1 6.9 2.6 2 1 1 3 3 3 2 Right handed beta helix region End_N_terminal PF12218.8 KFX93805.1 - 0.013 15.2 0.4 0.032 13.9 0.0 1.8 2 0 0 2 2 2 0 N terminal extension of bacteriophage endosialidase Seadorna_VP6 PF07407.11 KFX93805.1 - 0.25 10.3 0.9 0.34 9.8 0.9 1.2 1 0 0 1 1 1 0 Seadornavirus VP6 protein Transp_cyt_pur PF02133.15 KFX93807.1 - 2.4e-19 69.4 33.0 4.5e-19 68.6 33.0 1.5 1 1 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Proton_antipo_C PF01010.19 KFX93807.1 - 0.0096 15.6 0.1 0.85 9.2 0.0 2.4 2 0 0 2 2 2 2 NADH-dehyrogenase subunit F, TMs, (complex I) C-terminus p450 PF00067.22 KFX93808.1 - 7.2e-61 206.3 0.0 8.7e-61 206.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 NACHT PF05729.12 KFX93809.1 - 8.8e-12 45.2 0.0 5.8e-09 36.1 0.0 2.7 2 1 0 2 2 2 2 NACHT domain AAA_22 PF13401.6 KFX93809.1 - 7e-11 42.5 0.0 0.00039 20.7 0.0 3.4 3 0 0 3 3 3 2 AAA domain NB-ARC PF00931.22 KFX93809.1 - 1.4e-07 31.0 0.0 0.0003 20.1 0.0 2.5 2 0 0 2 2 2 2 NB-ARC domain AAA_16 PF13191.6 KFX93809.1 - 7.8e-07 29.6 0.0 0.0061 17.0 0.0 3.8 3 1 0 3 3 3 2 AAA ATPase domain AAA PF00004.29 KFX93809.1 - 4.6e-05 23.9 0.0 0.098 13.1 0.0 3.5 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 KFX93809.1 - 0.00042 20.3 0.0 0.046 13.7 0.0 3.2 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) ATPase_2 PF01637.18 KFX93809.1 - 0.00044 20.3 0.0 0.017 15.0 0.0 2.4 2 0 0 2 2 2 1 ATPase domain predominantly from Archaea AAA_14 PF13173.6 KFX93809.1 - 0.00098 19.2 0.5 3.5 7.7 0.1 3.6 3 1 0 3 3 3 2 AAA domain IstB_IS21 PF01695.17 KFX93809.1 - 0.0012 18.7 0.0 0.45 10.2 0.0 2.7 2 0 0 2 2 2 1 IstB-like ATP binding protein KAP_NTPase PF07693.14 KFX93809.1 - 0.0035 16.6 0.1 0.007 15.6 0.1 1.6 1 1 0 1 1 1 1 KAP family P-loop domain AAA_7 PF12775.7 KFX93809.1 - 0.0059 16.1 0.0 0.24 10.9 0.0 2.5 2 0 0 2 2 2 1 P-loop containing dynein motor region RNA_helicase PF00910.22 KFX93809.1 - 0.01 16.2 0.0 2.1 8.8 0.0 2.8 2 0 0 2 2 2 0 RNA helicase AAA_25 PF13481.6 KFX93809.1 - 0.013 15.1 0.0 3.4 7.2 0.0 2.8 2 1 0 2 2 2 0 AAA domain ABC_tran PF00005.27 KFX93809.1 - 0.014 15.9 0.2 6 7.4 0.0 3.4 3 0 0 3 3 3 0 ABC transporter AAA_19 PF13245.6 KFX93809.1 - 0.015 15.6 0.0 0.12 12.7 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 KFX93809.1 - 0.023 14.9 0.0 13 5.9 0.0 2.9 2 0 0 2 2 2 0 AAA domain Roc PF08477.13 KFX93809.1 - 0.039 14.2 0.0 1.1 9.4 0.0 2.6 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase CbiG_C PF01890.16 KFX93809.1 - 0.056 14.0 0.1 0.15 12.6 0.1 1.7 1 0 0 1 1 1 0 Cobalamin synthesis G C-terminus AAA_24 PF13479.6 KFX93809.1 - 0.1 12.3 0.5 5.2 6.7 0.2 2.6 2 1 0 2 2 2 0 AAA domain Ribosomal_S4Pg PF11993.8 KFX93809.1 - 0.12 12.4 0.6 0.29 11.2 0.6 1.5 1 0 0 1 1 1 0 Ribosomal S4P (gammaproteobacterial) GMC_oxred_N PF00732.19 KFX93810.1 - 1.6e-47 162.4 0.0 2.8e-47 161.5 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KFX93810.1 - 1.9e-36 125.7 0.1 4.3e-36 124.6 0.1 1.7 1 0 0 1 1 1 1 GMC oxidoreductase Ank_2 PF12796.7 KFX93810.1 - 1.5e-22 79.9 0.3 1.5e-07 31.9 0.4 4.7 1 1 1 4 4 4 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KFX93810.1 - 1.4e-19 69.9 1.1 5.9e-09 36.0 0.0 5.2 5 1 1 6 6 5 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 KFX93810.1 - 2e-16 60.1 6.9 1.2e-05 25.8 0.1 6.8 4 1 3 7 7 7 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFX93810.1 - 1.8e-13 49.4 2.6 0.089 13.4 0.0 8.7 10 0 0 10 10 8 2 Ankyrin repeat Ank PF00023.30 KFX93810.1 - 2.3e-11 43.6 2.3 0.00024 21.4 0.0 5.6 6 0 0 6 6 4 2 Ankyrin repeat AAA_16 PF13191.6 KFX93810.1 - 2.7e-05 24.6 0.0 8e-05 23.1 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain Zeta_toxin PF06414.12 KFX93810.1 - 8e-05 22.0 0.1 0.00073 18.9 0.0 2.2 2 0 0 2 2 2 1 Zeta toxin Pyr_redox_2 PF07992.14 KFX93810.1 - 0.00013 21.3 0.1 0.00045 19.5 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase AAA_22 PF13401.6 KFX93810.1 - 0.00032 21.0 0.0 0.001 19.4 0.0 1.8 1 0 0 1 1 1 1 AAA domain PGAP1 PF07819.13 KFX93810.1 - 0.00073 19.3 0.0 0.0017 18.1 0.0 1.6 1 0 0 1 1 1 1 PGAP1-like protein DAO PF01266.24 KFX93810.1 - 0.0011 18.6 1.9 0.0054 16.4 2.0 2.0 2 0 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.17 KFX93810.1 - 0.0011 18.2 0.9 0.0052 16.1 0.2 2.2 2 0 0 2 2 2 1 Thi4 family Lycopene_cycl PF05834.12 KFX93810.1 - 0.0023 17.0 0.2 0.0045 16.1 0.2 1.4 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_binding_2 PF00890.24 KFX93810.1 - 0.0025 17.0 1.5 0.057 12.5 1.6 2.3 2 0 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.6 KFX93810.1 - 0.0031 17.7 4.9 0.006 16.8 0.8 3.0 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 KFX93810.1 - 0.0064 15.8 0.3 1.3 8.3 0.3 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase AAA_25 PF13481.6 KFX93810.1 - 0.0074 15.9 0.0 0.015 14.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain NACHT PF05729.12 KFX93810.1 - 0.014 15.4 0.0 0.035 14.0 0.0 1.7 1 0 0 1 1 1 0 NACHT domain Hydrolase_4 PF12146.8 KFX93810.1 - 0.018 14.3 0.0 0.088 12.1 0.0 2.2 3 0 0 3 3 3 0 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KFX93810.1 - 0.022 15.4 0.0 0.052 14.2 0.0 1.7 1 0 0 1 1 1 0 Alpha/beta hydrolase family LCAT PF02450.15 KFX93810.1 - 0.043 13.0 0.0 0.074 12.2 0.0 1.3 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase Torsin PF06309.11 KFX93810.1 - 0.095 12.8 0.0 0.24 11.5 0.0 1.7 1 0 0 1 1 1 0 Torsin Glyco_hydro_3 PF00933.21 KFX93811.1 - 4.6e-60 203.6 0.0 6.2e-60 203.2 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.22 KFX93811.1 - 2.7e-50 171.2 0.0 4.4e-50 170.5 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.6 KFX93811.1 - 2.9e-22 78.5 0.9 2.9e-22 78.5 0.9 2.4 2 0 0 2 2 2 1 Fibronectin type III-like domain Sugar-bind PF04198.13 KFX93811.1 - 0.024 13.8 0.0 0.042 13.0 0.0 1.3 1 0 0 1 1 1 0 Putative sugar-binding domain DUF11 PF01345.18 KFX93811.1 - 0.076 13.3 0.4 0.2 12.0 0.4 1.7 1 0 0 1 1 1 0 Domain of unknown function DUF11 Sugar_tr PF00083.24 KFX93812.1 - 1.9e-93 313.8 27.6 2.2e-93 313.6 27.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KFX93812.1 - 1.3e-25 90.1 43.1 4.9e-25 88.2 24.7 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 KFX93812.1 - 1.3e-06 27.2 2.7 2.4e-06 26.3 2.7 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF3021 PF11457.8 KFX93812.1 - 0.0083 16.5 5.1 0.0083 16.5 5.1 3.1 2 1 0 2 2 2 1 Protein of unknown function (DUF3021) UPF0060 PF02694.15 KFX93812.1 - 0.056 13.7 0.3 0.056 13.7 0.3 2.6 2 0 0 2 2 2 0 Uncharacterised BCR, YnfA/UPF0060 family DUF2530 PF10745.9 KFX93812.1 - 0.12 12.7 9.1 6.7 7.0 3.1 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF2530) Acyl-CoA_ox_N PF14749.6 KFX93816.1 - 3.1e-27 95.6 0.6 4.9e-27 95.0 0.6 1.3 1 0 0 1 1 1 1 Acyl-coenzyme A oxidase N-terminal Acyl-CoA_dh_M PF02770.19 KFX93816.1 - 5.4e-06 26.5 0.0 1.3e-05 25.3 0.0 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 KFX93816.1 - 0.035 14.8 0.0 0.076 13.7 0.0 1.6 1 0 0 1 1 1 0 Acyl-CoA dehydrogenase, N-terminal domain MFS_1 PF07690.16 KFX93817.1 - 1.7e-28 99.6 37.5 1.7e-28 99.6 37.5 1.7 1 1 1 2 2 2 1 Major Facilitator Superfamily OATP PF03137.20 KFX93817.1 - 0.1 10.9 10.8 0.024 12.9 6.1 2.2 2 1 1 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family AMP-binding PF00501.28 KFX93818.1 - 1.3e-54 185.5 0.0 1.6e-54 185.2 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KFX93818.1 - 8.4e-11 42.7 0.0 2.7e-10 41.1 0.0 1.9 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain tRNA_bind PF01588.20 KFX93844.1 - 2.4e-21 75.7 0.1 4.5e-21 74.8 0.1 1.5 1 0 0 1 1 1 1 Putative tRNA binding domain GST_C_2 PF13410.6 KFX93844.1 - 0.002 18.1 0.0 0.0043 17.1 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Fungal_trans PF04082.18 KFX93845.1 - 2.7e-28 98.8 0.0 2.1e-27 95.9 0.0 2.2 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KFX93845.1 - 2.1e-09 37.4 8.9 3.6e-09 36.6 8.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 KFX93845.1 - 0.074 11.9 0.0 0.14 10.9 0.0 1.4 1 0 0 1 1 1 0 Fungal specific transcription factor domain eIF-5_eIF-2B PF01873.17 KFX93852.1 - 8.2e-42 141.8 0.3 1.2e-41 141.2 0.3 1.2 1 0 0 1 1 1 1 Domain found in IF2B/IF5 zf-HYPF PF07503.12 KFX93852.1 - 1.9 8.3 6.4 18 5.2 4.5 2.8 2 1 1 3 3 3 0 HypF finger Arc_trans_TRASH PF08394.10 KFX93852.1 - 2.9 8.3 6.7 2.5 8.5 0.2 2.7 1 1 1 2 2 2 0 Archaeal TRASH domain GET2 PF08690.10 KFX93852.1 - 3.6 7.2 6.2 6.1 6.4 6.2 1.4 1 0 0 1 1 1 0 GET complex subunit GET2 FR47 PF08445.10 KFX93861.1 - 3.5e-05 23.7 0.1 8e-05 22.5 0.1 1.5 2 0 0 2 2 2 1 FR47-like protein Acetyltransf_10 PF13673.7 KFX93861.1 - 0.0048 16.8 0.0 0.0067 16.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KFX93861.1 - 0.018 15.4 0.0 0.035 14.5 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KFX93861.1 - 0.049 13.9 0.0 0.087 13.1 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family zf-C3HC4 PF00097.25 KFX93862.1 - 9.6e-09 35.0 3.9 9.6e-09 35.0 3.9 5.4 6 1 0 6 6 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KFX93862.1 - 1.3e-07 31.5 2.7 1.3e-07 31.5 2.7 4.1 5 0 0 5 5 5 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 KFX93862.1 - 1.6e-06 27.8 3.7 1.6e-06 27.8 3.7 4.4 5 2 0 5 5 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KFX93862.1 - 6.6e-06 26.4 4.3 6.6e-06 26.4 4.3 4.9 4 1 1 5 5 3 1 Ring finger domain zf-RING_6 PF14835.6 KFX93862.1 - 2.9e-05 23.9 0.9 2.9e-05 23.9 0.9 3.1 3 1 0 3 3 2 1 zf-RING of BARD1-type protein zf-RING_5 PF14634.6 KFX93862.1 - 4.9e-05 23.2 3.4 4.9e-05 23.2 3.4 5.8 5 2 0 5 5 4 1 zinc-RING finger domain GAGA PF09237.11 KFX93862.1 - 0.00078 19.2 1.6 0.0085 15.9 0.6 2.6 2 0 0 2 2 2 1 GAGA factor SH3_9 PF14604.6 KFX93862.1 - 0.0027 17.5 0.1 0.0027 17.5 0.1 1.9 2 0 0 2 2 1 1 Variant SH3 domain zf-C3HC4_4 PF15227.6 KFX93862.1 - 0.0081 16.3 5.2 0.0081 16.3 5.2 5.2 6 1 0 6 6 4 1 zinc finger of C3HC4-type, RING Tmpp129 PF10272.9 KFX93862.1 - 0.02 14.2 1.2 0.045 13.0 1.2 1.5 1 0 0 1 1 1 0 Putative transmembrane protein precursor SH3_1 PF00018.28 KFX93862.1 - 0.033 13.8 0.0 0.086 12.5 0.0 1.7 1 0 0 1 1 1 0 SH3 domain EBP PF05241.12 KFX93863.1 - 1.9e-63 213.1 11.6 2.3e-63 212.9 11.6 1.0 1 0 0 1 1 1 1 Emopamil binding protein TMEM208_SND2 PF05620.11 KFX93863.1 - 0.042 13.6 0.5 0.042 13.6 0.5 2.7 3 1 1 4 4 4 0 SRP-independent targeting protein 2/TMEM208 NADH_dh_m_C1 PF15088.6 KFX93863.1 - 0.44 10.2 4.1 1.7 8.3 1.2 2.7 3 0 0 3 3 3 0 NADH dehydrogenase [ubiquinone] 1 subunit C1, mitochondrial IBR PF01485.21 KFX93864.1 - 1e-17 64.1 31.5 9e-12 45.0 1.5 4.0 3 1 1 4 4 4 3 IBR domain, a half RING-finger domain RWD PF05773.22 KFX93864.1 - 1.2e-17 64.3 0.2 2.3e-17 63.3 0.2 1.5 1 0 0 1 1 1 1 RWD domain zf-RING_2 PF13639.6 KFX93864.1 - 0.00015 22.0 5.2 0.00015 22.0 5.2 4.3 4 1 1 5 5 5 2 Ring finger domain zf-RING_UBOX PF13445.6 KFX93864.1 - 0.00023 21.1 5.8 0.00023 21.1 5.8 3.8 3 0 0 3 3 3 2 RING-type zinc-finger zf-RING_5 PF14634.6 KFX93864.1 - 0.0024 17.8 6.2 0.0024 17.8 6.2 4.0 3 1 1 4 4 4 1 zinc-RING finger domain zf-C3HC4 PF00097.25 KFX93864.1 - 0.015 15.1 5.4 0.015 15.1 5.4 4.4 4 1 0 4 4 4 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 KFX93864.1 - 0.044 14.0 0.6 0.044 14.0 0.6 4.6 5 1 0 5 5 5 0 zinc finger of C3HC4-type, RING DUF1244 PF06844.11 KFX93864.1 - 0.43 10.8 2.8 3.2 8.0 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1244) FYVE PF01363.21 KFX93864.1 - 1 9.5 25.6 7 6.9 7.3 3.5 2 1 0 2 2 2 0 FYVE zinc finger NDT80_PhoG PF05224.12 KFX93865.1 - 1.1e-30 107.3 0.0 3.4e-30 105.6 0.0 1.9 1 0 0 1 1 1 1 NDT80 / PhoG like DNA-binding family DUF2011 PF09428.10 KFX93866.1 - 3.1e-21 75.4 0.0 7.7e-21 74.2 0.0 1.7 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF2011) Ank_2 PF12796.7 KFX93877.1 - 3e-78 258.4 0.2 1.1e-13 51.5 0.0 7.6 2 2 6 8 8 8 8 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KFX93877.1 - 1.9e-53 178.1 0.0 5.4e-09 36.4 0.0 9.2 4 3 7 11 11 11 9 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFX93877.1 - 4.6e-50 161.8 1.2 0.0049 17.3 0.0 13.6 13 0 0 13 13 13 10 Ankyrin repeat Ank PF00023.30 KFX93877.1 - 3.6e-47 156.8 10.5 0.00018 21.8 0.1 13.9 14 0 0 14 14 14 9 Ankyrin repeat Ank_5 PF13857.6 KFX93877.1 - 1.8e-40 136.4 7.7 6.7e-06 26.3 0.0 11.6 2 2 11 13 13 13 11 Ankyrin repeats (many copies) DUF676 PF05057.14 KFX93877.1 - 0.0023 17.5 0.0 0.0036 16.8 0.0 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) PGAP1 PF07819.13 KFX93877.1 - 0.0048 16.6 0.0 0.01 15.6 0.0 1.5 1 0 0 1 1 1 1 PGAP1-like protein SR1P PF13790.6 KFX93877.1 - 0.0081 16.3 1.4 0.57 10.3 0.3 2.7 2 0 0 2 2 2 1 SR1 protein Ser_hydrolase PF06821.13 KFX93877.1 - 0.0088 15.9 0.0 0.29 11.0 0.0 2.9 3 0 0 3 3 3 1 Serine hydrolase Abhydrolase_6 PF12697.7 KFX93877.1 - 0.011 16.4 0.0 0.042 14.4 0.0 2.2 1 1 0 1 1 1 0 Alpha/beta hydrolase family LIDHydrolase PF10230.9 KFX93877.1 - 0.047 13.3 0.0 0.078 12.5 0.0 1.2 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase LCAT PF02450.15 KFX93877.1 - 0.1 11.7 0.0 0.17 11.1 0.0 1.2 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase FHA PF00498.26 KFX93878.1 - 1.1e-16 61.0 0.1 3.2e-16 59.4 0.0 1.9 2 0 0 2 2 2 1 FHA domain Yop-YscD_cpl PF16697.5 KFX93878.1 - 0.00043 20.5 0.0 0.0012 19.2 0.0 1.7 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain Med21 PF11221.8 KFX93878.1 - 0.0024 18.1 4.8 0.0024 18.1 4.8 3.7 4 1 0 4 4 4 1 Subunit 21 of Mediator complex Uds1 PF15456.6 KFX93878.1 - 0.003 17.7 5.6 0.003 17.7 5.6 3.0 2 1 1 3 3 3 1 Up-regulated During Septation YhfZ_C PF14503.6 KFX93878.1 - 0.09 12.3 0.0 0.09 12.3 0.0 1.8 2 0 0 2 2 2 0 YhfZ C-terminal domain TUDOR PF00567.24 KFX93878.1 - 0.16 12.0 0.6 4 7.5 0.0 2.7 2 0 0 2 2 2 0 Tudor domain Med9 PF07544.13 KFX93878.1 - 0.17 12.0 6.1 7.4 6.7 0.0 2.7 2 0 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 LMBR1 PF04791.16 KFX93878.1 - 1.7 7.5 5.2 1.3 7.8 0.3 2.1 2 0 0 2 2 2 0 LMBR1-like membrane protein OmpH PF03938.14 KFX93878.1 - 3.3 8.0 21.2 3.6 7.9 3.0 2.5 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) Spt5_N PF11942.8 KFX93878.1 - 4.5 8.3 13.3 0.22 12.5 2.0 3.1 3 0 0 3 3 3 0 Spt5 transcription elongation factor, acidic N-terminal DUF3405 PF11885.8 KFX93881.1 - 2.5e-173 577.4 0.2 3.1e-173 577.1 0.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3405) Nefa_Nip30_N PF10187.9 KFX93882.1 - 7.7e-33 113.0 6.7 7.7e-33 113.0 6.7 2.7 2 1 1 3 3 3 1 N-terminal domain of NEFA-interacting nuclear protein NIP30 UVR PF02151.19 KFX93882.1 - 2.1 8.2 8.5 0.16 11.7 2.9 2.1 2 0 0 2 2 2 0 UvrB/uvrC motif Aldo_ket_red PF00248.21 KFX93883.1 - 2.2e-46 158.4 0.0 8.3e-45 153.2 0.0 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family PI-PLC-X PF00388.19 KFX93884.1 - 3e-12 46.4 0.0 4.7e-12 45.7 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain DUF4998 PF16389.5 KFX93884.1 - 0.19 11.3 0.1 0.3 10.6 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function Ribosomal_L10 PF00466.20 KFX93885.1 - 0.0002 21.4 0.0 0.0044 17.1 0.0 2.3 2 0 0 2 2 2 1 Ribosomal protein L10 Glycos_transf_3 PF00591.21 KFX93886.1 - 1.5e-61 208.2 0.0 2.3e-61 207.6 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family, a/b domain Glycos_trans_3N PF02885.17 KFX93886.1 - 1e-16 60.5 0.2 3.8e-16 58.7 0.0 2.0 2 0 0 2 2 2 1 Glycosyl transferase family, helical bundle domain CcdA PF07362.12 KFX93886.1 - 0.054 13.9 0.6 0.14 12.6 0.6 1.7 1 0 0 1 1 1 0 Post-segregation antitoxin CcdA DNA_RNApol_7kD PF03604.13 KFX93887.1 - 2.7e-18 65.3 5.1 3.6e-18 64.9 5.1 1.2 1 0 0 1 1 1 1 DNA directed RNA polymerase, 7 kDa subunit zf_UBZ PF18439.1 KFX93887.1 - 0.0021 17.6 0.9 0.92 9.2 0.1 2.2 2 0 0 2 2 2 2 Ubiquitin-Binding Zinc Finger DZR PF12773.7 KFX93887.1 - 0.0053 16.8 0.3 0.0073 16.3 0.3 1.2 1 0 0 1 1 1 1 Double zinc ribbon DUF2197 PF09963.9 KFX93887.1 - 0.012 15.9 1.6 1.1 9.6 0.1 2.1 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2197) GFA PF04828.14 KFX93887.1 - 0.014 15.7 0.2 3 8.2 0.0 2.1 1 1 1 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme TFIIS_C PF01096.18 KFX93887.1 - 0.016 15.1 0.7 4.5 7.2 0.2 2.3 2 0 0 2 2 2 0 Transcription factor S-II (TFIIS) HypA PF01155.19 KFX93887.1 - 0.029 14.4 0.2 0.033 14.2 0.2 1.1 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zinc-ribbon_6 PF10005.9 KFX93887.1 - 0.033 14.9 0.1 0.043 14.5 0.1 1.2 1 0 0 1 1 1 0 zinc-ribbon domain DUF3268 PF11672.8 KFX93887.1 - 0.086 13.2 0.2 0.47 10.8 0.2 1.8 1 1 0 1 1 1 0 zinc-finger-containing domain Zn_ribbon_recom PF13408.6 KFX93887.1 - 0.098 13.2 2.4 1.6 9.3 0.2 2.2 2 0 0 2 2 2 0 Recombinase zinc beta ribbon domain LRV_FeS PF05484.11 KFX93887.1 - 0.12 12.4 1.3 0.13 12.3 0.2 1.6 1 1 1 2 2 2 0 LRV protein FeS4 cluster Zn-ribbon_8 PF09723.10 KFX93887.1 - 0.2 11.8 2.7 0.53 10.5 2.7 1.7 1 1 0 1 1 1 0 Zinc ribbon domain ATP_bind_1 PF03029.17 KFX93888.1 - 5.8e-66 222.7 0.0 1.1e-65 221.8 0.0 1.4 1 1 0 1 1 1 1 Conserved hypothetical ATP binding protein MeaB PF03308.16 KFX93888.1 - 6.1e-07 28.7 0.1 0.0012 17.9 0.0 2.2 2 0 0 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB GTP_EFTU PF00009.27 KFX93888.1 - 6.5e-06 25.8 0.0 0.00083 18.9 0.0 2.8 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain PRK PF00485.18 KFX93888.1 - 0.00026 20.8 0.0 0.00073 19.3 0.0 1.7 2 0 0 2 2 1 1 Phosphoribulokinase / Uridine kinase family AAA_22 PF13401.6 KFX93888.1 - 0.00043 20.6 0.0 0.0014 18.9 0.0 2.0 1 1 0 1 1 1 1 AAA domain SRP54 PF00448.22 KFX93888.1 - 0.00051 19.7 0.0 0.022 14.4 0.0 3.0 3 0 0 3 3 3 1 SRP54-type protein, GTPase domain AAA_24 PF13479.6 KFX93888.1 - 0.00053 19.8 0.0 0.0011 18.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 KFX93888.1 - 0.00086 19.5 0.3 0.0037 17.4 0.0 2.1 2 0 0 2 2 2 1 AAA domain G-alpha PF00503.20 KFX93888.1 - 0.001 18.3 0.1 0.05 12.8 0.0 2.5 2 1 0 2 2 2 1 G-protein alpha subunit MMR_HSR1 PF01926.23 KFX93888.1 - 0.0018 18.3 0.0 0.014 15.4 0.0 2.2 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.6 KFX93888.1 - 0.002 18.6 0.0 0.0053 17.1 0.0 2.1 1 1 0 1 1 1 1 AAA ATPase domain NACHT PF05729.12 KFX93888.1 - 0.002 18.1 0.0 0.0068 16.3 0.0 1.8 2 0 0 2 2 2 1 NACHT domain Arf PF00025.21 KFX93888.1 - 0.002 17.6 0.0 0.68 9.4 0.0 2.6 2 1 0 2 2 2 1 ADP-ribosylation factor family NB-ARC PF00931.22 KFX93888.1 - 0.0024 17.1 0.0 0.0057 15.9 0.0 1.5 1 0 0 1 1 1 1 NB-ARC domain FeoB_N PF02421.18 KFX93888.1 - 0.0029 17.1 0.0 0.095 12.2 0.0 2.5 3 0 0 3 3 3 1 Ferrous iron transport protein B AAA_30 PF13604.6 KFX93888.1 - 0.0032 17.2 0.0 0.0049 16.6 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_7 PF12775.7 KFX93888.1 - 0.0053 16.3 0.0 0.012 15.2 0.0 1.5 1 0 0 1 1 1 1 P-loop containing dynein motor region Roc PF08477.13 KFX93888.1 - 0.0055 16.9 0.0 0.84 9.9 0.0 2.5 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase cobW PF02492.19 KFX93888.1 - 0.0092 15.6 0.0 0.69 9.5 0.0 2.4 2 1 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain RsgA_GTPase PF03193.16 KFX93888.1 - 0.017 15.0 0.0 6.3 6.7 0.0 3.0 3 0 0 3 3 3 0 RsgA GTPase PduV-EutP PF10662.9 KFX93888.1 - 0.04 13.7 0.1 0.39 10.4 0.0 2.5 3 1 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation Zeta_toxin PF06414.12 KFX93888.1 - 0.1 11.9 0.0 0.22 10.8 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin AAA_18 PF13238.6 KFX93888.1 - 0.51 10.9 0.0 0.51 10.9 0.0 2.3 3 1 0 3 3 1 0 AAA domain CwfJ_C_2 PF04676.14 KFX93889.1 - 1.7e-30 105.8 0.1 8.7e-30 103.5 0.1 2.4 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 2 CwfJ_C_1 PF04677.15 KFX93889.1 - 7.9e-28 96.8 0.0 1.3e-27 96.1 0.0 1.3 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 SET_assoc PF11767.8 KFX93889.1 - 0.13 11.9 0.1 0.47 10.1 0.0 2.0 2 0 0 2 2 2 0 Histone lysine methyltransferase SET associated Zn_clus PF00172.18 KFX93890.1 - 1.5e-08 34.6 10.6 2.2e-08 34.1 10.6 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CRPV_capsid PF08762.10 KFX93890.1 - 0.035 13.8 1.3 0.056 13.1 1.3 1.3 1 0 0 1 1 1 0 CRPV capsid protein like eIF-3_zeta PF05091.12 KFX93890.1 - 0.071 12.1 4.8 0.089 11.8 4.8 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Band_3_cyto PF07565.13 KFX93890.1 - 0.27 11.0 3.6 0.43 10.4 3.6 1.4 1 0 0 1 1 1 0 Band 3 cytoplasmic domain RR_TM4-6 PF06459.12 KFX93890.1 - 0.32 10.8 4.4 0.47 10.2 4.4 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Presenilin PF01080.17 KFX93890.1 - 0.44 9.2 7.8 0.58 8.9 7.8 1.2 1 0 0 1 1 1 0 Presenilin DUF2347 PF09804.9 KFX93890.1 - 0.82 9.2 2.9 1.5 8.4 2.9 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2347) DUF4175 PF13779.6 KFX93890.1 - 2.4 5.9 21.4 3.4 5.5 21.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) EIIBC-GUT_N PF03612.14 KFX93890.1 - 3.7 7.3 5.9 6.5 6.5 5.9 1.3 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus cwf18 PF08315.12 KFX93890.1 - 3.8 8.2 10.4 6.9 7.3 10.4 1.5 1 1 0 1 1 1 0 cwf18 pre-mRNA splicing factor DUF4407 PF14362.6 KFX93890.1 - 4 6.7 5.8 6.3 6.1 5.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) V_ATPase_I PF01496.19 KFX93890.1 - 4.1 5.2 6.1 5.8 4.7 6.1 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Spt20 PF12090.8 KFX93890.1 - 8.8 5.9 37.1 0.24 11.0 26.3 2.2 2 0 0 2 2 2 0 Spt20 family CENP-S PF15630.6 KFX93892.1 - 4.5e-34 116.7 0.0 1.3e-33 115.2 0.0 1.7 2 0 0 2 2 2 1 CENP-S protein CENP-T_C PF15511.6 KFX93892.1 - 8.6e-07 29.0 0.0 1.4e-06 28.4 0.0 1.3 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold Bromo_TP PF07524.13 KFX93892.1 - 0.0023 17.9 0.0 0.0062 16.5 0.0 1.6 2 0 0 2 2 2 1 Bromodomain associated Histone PF00125.24 KFX93892.1 - 0.088 13.2 0.0 0.16 12.4 0.0 1.4 1 0 0 1 1 1 0 Core histone H2A/H2B/H3/H4 APC_r PF05923.12 KFX93892.1 - 0.31 10.8 2.0 0.37 10.6 0.1 1.9 2 0 0 2 2 2 0 APC repeat Glyco_hydro_35 PF01301.19 KFX93893.1 - 3.2e-83 280.0 0.4 4e-83 279.7 0.4 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 BetaGal_dom4_5 PF13364.6 KFX93893.1 - 1.8e-06 28.5 0.0 0.0031 18.1 0.0 3.0 3 0 0 3 3 3 2 Beta-galactosidase jelly roll domain ADH_zinc_N PF00107.26 KFX93894.1 - 2e-20 73.1 0.0 6.6e-20 71.4 0.0 1.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KFX93894.1 - 2.2e-15 57.9 0.0 4.4e-15 56.9 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KFX93894.1 - 2.7e-09 36.9 0.0 8.2e-09 35.3 0.0 1.8 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain Nairo_nucleo PF02477.15 KFX93894.1 - 0.11 11.3 0.0 0.2 10.4 0.0 1.3 1 0 0 1 1 1 0 Nucleocapsid N protein Tudor_FRX1 PF18336.1 KFX93895.1 - 0.032 14.1 0.0 0.051 13.5 0.0 1.4 1 0 0 1 1 1 0 Fragile X mental retardation Tudor domain HATPase_c_3 PF13589.6 KFX93897.1 - 0.0022 17.8 0.0 0.0048 16.7 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Peptidase_M18 PF02127.15 KFX93899.1 - 4.8e-137 457.3 0.0 8.7e-137 456.4 0.0 1.4 1 1 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) SNF2_N PF00176.23 KFX93900.1 - 2.4e-64 217.3 0.4 4.7e-64 216.3 0.4 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain DBINO PF13892.6 KFX93900.1 - 1.7e-49 167.6 20.0 1.7e-49 167.6 20.0 4.0 4 1 0 4 4 4 1 DNA-binding domain Helicase_C PF00271.31 KFX93900.1 - 1.7e-19 70.2 0.0 1.1e-18 67.6 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KFX93900.1 - 2e-06 27.9 0.0 2e-06 27.9 0.0 3.0 3 1 0 3 3 3 1 Type III restriction enzyme, res subunit DEAD PF00270.29 KFX93900.1 - 0.00082 19.2 0.0 0.0025 17.6 0.0 1.9 1 0 0 1 1 1 1 DEAD/DEAH box helicase HDA2-3 PF11496.8 KFX93900.1 - 0.27 10.3 0.0 0.27 10.3 0.0 2.7 4 0 0 4 4 4 0 Class II histone deacetylase complex subunits 2 and 3 ABC_tran PF00005.27 KFX93901.1 - 2.7e-48 163.9 0.0 1.1e-27 97.2 0.0 2.7 3 0 0 3 3 2 2 ABC transporter ABC_membrane PF00664.23 KFX93901.1 - 2.7e-29 102.7 27.8 1.1e-21 77.7 11.2 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region AAA_21 PF13304.6 KFX93901.1 - 5.5e-12 46.1 5.5 0.016 15.1 0.0 4.6 4 0 0 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 KFX93901.1 - 4.9e-10 39.2 5.1 0.12 11.8 0.0 4.2 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 KFX93901.1 - 9.9e-09 34.8 0.8 0.00055 19.6 0.1 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 KFX93901.1 - 3.3e-06 27.1 0.2 0.16 12.0 0.1 2.9 3 0 0 3 3 2 2 50S ribosome-binding GTPase AAA_16 PF13191.6 KFX93901.1 - 5.2e-06 26.9 0.3 0.14 12.6 0.1 2.7 2 0 0 2 2 2 2 AAA ATPase domain RsgA_GTPase PF03193.16 KFX93901.1 - 9e-06 25.7 0.2 0.063 13.2 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase AAA_22 PF13401.6 KFX93901.1 - 9.1e-06 26.0 0.8 0.021 15.1 0.1 3.3 3 0 0 3 3 2 1 AAA domain AAA_23 PF13476.6 KFX93901.1 - 0.00012 22.7 0.8 0.069 13.6 0.1 2.3 2 0 0 2 2 2 1 AAA domain FtsK_SpoIIIE PF01580.18 KFX93901.1 - 0.00031 20.2 0.4 0.22 10.8 0.0 2.5 2 0 0 2 2 2 2 FtsK/SpoIIIE family cobW PF02492.19 KFX93901.1 - 0.00036 20.2 1.5 0.057 13.0 0.3 2.3 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain NTPase_1 PF03266.15 KFX93901.1 - 0.00057 19.8 2.5 0.17 11.8 0.8 2.4 2 0 0 2 2 2 1 NTPase T2SSE PF00437.20 KFX93901.1 - 0.001 18.2 0.3 0.017 14.2 0.1 2.2 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_7 PF12775.7 KFX93901.1 - 0.0012 18.4 0.2 0.4 10.2 0.1 2.3 2 0 0 2 2 2 1 P-loop containing dynein motor region DUF87 PF01935.17 KFX93901.1 - 0.0015 18.6 1.5 0.058 13.5 0.1 2.4 2 0 0 2 2 2 1 Helicase HerA, central domain AAA_30 PF13604.6 KFX93901.1 - 0.0023 17.7 0.4 0.2 11.4 0.1 2.5 2 1 0 2 2 2 1 AAA domain AAA PF00004.29 KFX93901.1 - 0.01 16.3 0.0 0.59 10.6 0.0 3.0 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Dynamin_N PF00350.23 KFX93901.1 - 0.013 15.6 4.1 0.11 12.6 0.1 2.4 2 0 0 2 2 2 0 Dynamin family Septin PF00735.18 KFX93901.1 - 0.013 14.8 0.4 2.2 7.5 0.1 2.3 2 0 0 2 2 2 0 Septin AAA_25 PF13481.6 KFX93901.1 - 0.018 14.7 0.2 0.24 11.0 0.2 2.3 2 0 0 2 2 2 0 AAA domain MeaB PF03308.16 KFX93901.1 - 0.021 13.8 0.6 4.8 6.1 0.0 2.2 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_18 PF13238.6 KFX93901.1 - 0.023 15.2 2.7 0.69 10.5 0.5 2.5 2 0 0 2 2 2 0 AAA domain DUF815 PF05673.13 KFX93901.1 - 0.024 13.8 0.2 1.4 8.0 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF815) ATP_bind_1 PF03029.17 KFX93901.1 - 0.025 14.4 0.7 1.6 8.4 0.2 2.4 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein RNA_helicase PF00910.22 KFX93901.1 - 0.028 14.8 0.3 13 6.3 0.1 3.1 3 0 0 3 3 2 0 RNA helicase AAA_24 PF13479.6 KFX93901.1 - 0.042 13.6 0.6 3.5 7.3 0.0 2.5 2 0 0 2 2 2 0 AAA domain ATPase_2 PF01637.18 KFX93901.1 - 0.042 13.8 0.1 3.7 7.4 0.0 2.9 3 0 0 3 3 2 0 ATPase domain predominantly from Archaea TrwB_AAD_bind PF10412.9 KFX93901.1 - 0.05 12.5 1.6 4.4 6.1 0.0 2.2 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain NACHT PF05729.12 KFX93901.1 - 0.054 13.4 1.0 8.4 6.3 0.2 2.6 2 0 0 2 2 2 0 NACHT domain ATP-synt_ab PF00006.25 KFX93901.1 - 0.054 13.1 0.1 2.2 7.9 0.0 2.3 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain NB-ARC PF00931.22 KFX93901.1 - 0.06 12.5 1.9 2.8 7.1 0.1 2.7 3 0 0 3 3 3 0 NB-ARC domain Roc PF08477.13 KFX93901.1 - 0.064 13.5 0.4 6.2 7.1 0.1 2.5 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_33 PF13671.6 KFX93901.1 - 0.1 12.8 1.7 3.2 7.9 0.3 2.4 2 0 0 2 2 2 0 AAA domain Sigma54_activat PF00158.26 KFX93901.1 - 0.11 12.1 0.0 20 4.8 0.0 2.3 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_5 PF07728.14 KFX93901.1 - 0.15 12.1 0.4 6.2 6.8 0.2 3.0 3 0 0 3 3 2 0 AAA domain (dynein-related subfamily) Zeta_toxin PF06414.12 KFX93901.1 - 0.17 11.2 1.2 11 5.3 0.3 2.4 2 0 0 2 2 2 0 Zeta toxin PRK PF00485.18 KFX93901.1 - 0.17 11.6 2.2 0.31 10.8 0.2 2.1 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family ATPase PF06745.13 KFX93901.1 - 0.28 10.5 1.5 17 4.7 0.3 3.1 3 0 0 3 3 3 0 KaiC Viral_helicase1 PF01443.18 KFX93901.1 - 0.4 10.4 1.2 1.7 8.3 0.1 2.2 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase AAA PF00004.29 KFX93902.1 - 3.7e-16 59.8 0.0 2e-15 57.4 0.0 2.2 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KFX93902.1 - 0.00058 20.2 2.7 0.014 15.7 0.1 3.2 3 1 0 4 4 4 1 AAA domain AAA_16 PF13191.6 KFX93902.1 - 0.002 18.5 0.0 0.0086 16.5 0.0 1.8 1 1 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.14 KFX93902.1 - 0.0057 16.7 0.0 0.014 15.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) CPT PF07931.12 KFX93902.1 - 0.018 14.9 0.0 0.14 12.0 0.0 2.2 1 1 1 2 2 2 0 Chloramphenicol phosphotransferase-like protein RuvB_N PF05496.12 KFX93902.1 - 0.081 12.7 0.0 0.16 11.7 0.0 1.5 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain IstB_IS21 PF01695.17 KFX93902.1 - 0.085 12.6 0.0 0.17 11.6 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_24 PF13479.6 KFX93902.1 - 0.086 12.5 0.0 0.28 10.9 0.0 1.9 1 0 0 1 1 1 0 AAA domain PGAP1 PF07819.13 KFX93904.1 - 0.00023 21.0 0.0 0.00043 20.1 0.0 1.4 1 0 0 1 1 1 1 PGAP1-like protein DUF676 PF05057.14 KFX93904.1 - 0.0062 16.1 0.0 0.01 15.3 0.0 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_6 PF12697.7 KFX93904.1 - 0.045 14.4 0.0 0.089 13.4 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase family DUF900 PF05990.12 KFX93904.1 - 0.19 11.2 0.0 2.4 7.6 0.0 2.3 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF900) QslA_E PF18226.1 KFX93905.1 - 0.12 12.3 0.1 0.31 11.0 0.1 1.7 1 0 0 1 1 1 0 LasR-specific antiactivator QslA chain E AA_permease PF00324.21 KFX93912.1 - 1.1e-124 416.7 40.0 1.3e-124 416.4 40.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KFX93912.1 - 8e-36 123.8 42.2 1.7e-35 122.7 42.3 1.4 1 1 0 1 1 1 1 Amino acid permease Ofd1_CTDD PF10637.9 KFX93913.1 - 4.5e-90 301.5 0.0 3.6e-87 291.9 0.0 2.3 2 0 0 2 2 2 2 Oxoglutarate and iron-dependent oxygenase degradation C-term 2OG-FeII_Oxy_4 PF13661.6 KFX93913.1 - 1.6e-25 89.6 0.0 6.9e-25 87.6 0.0 2.1 2 1 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_3 PF13640.6 KFX93913.1 - 1.4e-13 51.5 0.0 2.8e-13 50.6 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DUF1963 PF09234.10 KFX93913.1 - 0.042 14.3 0.1 0.11 12.9 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF1963) Tub_N PF16322.5 KFX93913.1 - 0.21 12.0 0.1 0.21 12.0 0.1 2.8 2 1 1 3 3 3 0 Tubby N-terminal BUD22 PF09073.10 KFX93913.1 - 7.1 5.9 22.9 0.88 8.8 17.1 2.1 2 0 0 2 2 2 0 BUD22 GFA PF04828.14 KFX93914.1 - 1.6e-07 31.5 9.5 3.6e-05 24.0 0.3 3.3 2 1 1 3 3 3 2 Glutathione-dependent formaldehyde-activating enzyme zf-NADH-PPase PF09297.11 KFX93914.1 - 0.0013 18.3 5.5 0.13 12.0 0.1 2.8 2 0 0 2 2 2 2 NADH pyrophosphatase zinc ribbon domain zf-CSL PF05207.13 KFX93914.1 - 0.0021 17.8 5.4 1.3 8.8 0.4 3.4 3 0 0 3 3 3 2 CSL zinc finger Nudix_N_2 PF14803.6 KFX93914.1 - 0.018 15.0 11.3 0.076 12.9 0.2 3.8 3 0 0 3 3 3 0 Nudix N-terminal zf_C2H2_13 PF18508.1 KFX93914.1 - 0.028 14.0 0.3 0.086 12.5 0.0 1.9 2 0 0 2 2 2 0 Zinc finger domain PknG_rubred PF16919.5 KFX93914.1 - 0.032 14.4 0.2 1.7 8.8 0.0 2.5 2 0 0 2 2 2 0 Protein kinase G rubredoxin domain MqsA_antitoxin PF15731.5 KFX93914.1 - 0.04 14.0 0.4 1.7 8.8 0.0 2.3 2 0 0 2 2 2 0 Antitoxin component of bacterial toxin-antitoxin system, MqsA DUF2321 PF10083.9 KFX93914.1 - 0.1 12.2 2.6 1.4 8.5 1.5 2.2 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2321) zinc_ribbon_2 PF13240.6 KFX93914.1 - 3.4 7.5 10.0 1.4 8.8 0.1 3.2 3 0 0 3 3 3 0 zinc-ribbon domain DZR PF12773.7 KFX93914.1 - 4.9 7.3 12.3 1.3 9.1 0.1 3.2 2 2 0 3 3 3 0 Double zinc ribbon DUF4472 PF14739.6 KFX93915.1 - 0.13 13.0 0.1 0.24 12.1 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4472) Co_AT_N PF12557.8 KFX93915.1 - 0.61 10.1 2.8 1.5 8.8 2.8 1.7 1 0 0 1 1 1 0 Cob(I)alamin adenosyltransferase N terminal Pkinase PF00069.25 KFX93917.1 - 1.2e-59 201.8 0.0 2.7e-59 200.7 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFX93917.1 - 4.1e-29 101.7 0.0 8.7e-29 100.6 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.26 KFX93917.1 - 9e-10 38.8 0.1 9.9e-09 35.4 0.1 2.5 2 0 0 2 2 2 1 FHA domain Yop-YscD_cpl PF16697.5 KFX93917.1 - 0.0009 19.5 0.0 0.0024 18.1 0.0 1.6 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain Kdo PF06293.14 KFX93917.1 - 0.0012 18.3 0.0 0.0022 17.4 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 KFX93917.1 - 0.056 13.0 0.0 0.1 12.2 0.0 1.3 1 0 0 1 1 1 0 RIO1 family Methyltranf_PUA PF13636.6 KFX93917.1 - 0.091 12.8 0.1 0.24 11.4 0.1 1.6 1 0 0 1 1 1 0 RNA-binding PUA-like domain of methyltransferase RsmF p450 PF00067.22 KFX93918.1 - 6.4e-50 170.2 0.0 9.8e-50 169.6 0.0 1.3 1 0 0 1 1 1 1 Cytochrome P450 RNase_T PF00929.24 KFX93920.1 - 6.7e-09 36.5 0.0 2.7e-08 34.5 0.0 2.1 1 1 0 1 1 1 1 Exonuclease Yippee-Mis18 PF03226.14 KFX93921.1 - 8.8e-05 22.7 0.1 0.00018 21.7 0.1 1.5 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly BLOC1_2 PF10046.9 KFX93921.1 - 0.21 11.9 2.4 1.8 8.9 0.5 2.6 1 1 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Sortilin-Vps10 PF15902.5 KFX93922.1 - 8.1e-289 957.6 20.1 3.3e-148 494.2 10.7 2.1 2 0 0 2 2 2 2 Sortilin, neurotensin receptor 3, Sortilin_C PF15901.5 KFX93922.1 - 1.2e-90 302.4 18.4 2.4e-46 158.2 2.8 2.3 2 0 0 2 2 2 2 Sortilin, neurotensin receptor 3, C-terminal BNR PF02012.20 KFX93922.1 - 4.8e-12 44.0 33.1 0.97 9.7 0.6 11.2 11 0 0 11 11 11 5 BNR/Asp-box repeat BNR_2 PF13088.6 KFX93922.1 - 6.3e-08 32.3 0.6 1.7 7.9 0.0 5.6 5 1 1 6 6 6 3 BNR repeat-like domain BNR_6 PF15899.5 KFX93922.1 - 3.8e-06 26.5 12.6 4.3 7.7 0.1 6.8 6 0 0 6 6 6 2 BNR-Asp box repeat PSII_BNR PF14870.6 KFX93922.1 - 0.00013 21.3 1.4 2.1 7.5 0.0 4.7 5 0 0 5 5 5 2 Photosynthesis system II assembly factor YCF48 CHB_HEX_C PF03174.13 KFX93922.1 - 0.024 14.6 2.2 5.7 7.0 0.1 4.0 5 0 0 5 5 5 0 Chitobiase/beta-hexosaminidase C-terminal domain BNR_3 PF13859.6 KFX93922.1 - 0.047 13.0 0.8 2.3 7.4 0.1 3.4 3 0 0 3 3 3 0 BNR repeat-like domain DUF659 PF04937.15 KFX93922.1 - 0.086 12.7 0.1 0.18 11.6 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF 659) preSET_CXC PF18264.1 KFX93922.1 - 2.6 8.6 7.3 2.5 8.6 0.9 2.6 2 0 0 2 2 2 0 CXC domain MTCP1 PF08991.10 KFX93935.1 - 1.2e-12 47.9 2.5 1.2e-12 47.9 2.5 1.7 2 0 0 2 2 2 1 Mature-T-Cell Proliferation I type CHCH PF06747.13 KFX93935.1 - 0.037 14.2 1.5 0.066 13.4 1.5 1.5 1 0 0 1 1 1 0 CHCH domain DSPc PF00782.20 KFX93936.1 - 4.6e-22 78.3 0.0 1.9e-19 69.8 0.0 2.2 2 0 0 2 2 2 2 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 KFX93936.1 - 0.0068 16.0 0.0 0.0098 15.5 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Init_tRNA_PT PF04179.12 KFX93936.1 - 0.097 13.0 0.0 0.2 12.0 0.0 1.5 1 0 0 1 1 1 0 Rit1 DUSP-like domain Suc_Fer-like PF06999.12 KFX93944.1 - 1.2e-70 237.4 0.0 2.9e-70 236.1 0.0 1.6 2 0 0 2 2 2 1 Sucrase/ferredoxin-like Drf_GBD PF06371.13 KFX93944.1 - 1.2e-14 54.4 2.1 1.2e-14 54.4 2.1 2.7 2 1 0 2 2 2 1 Diaphanous GTPase-binding Domain Glyco_hydro_43 PF04616.14 KFX93946.1 - 1.7e-63 214.7 3.0 2.1e-63 214.3 3.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 GH43_C2 PF17851.1 KFX93946.1 - 6.8e-14 52.1 0.0 1.2e-13 51.2 0.0 1.4 1 0 0 1 1 1 1 Beta xylosidase C-terminal Concanavalin A-like domain DnaJ PF00226.31 KFX93954.1 - 1e-06 28.8 0.0 1.9e-06 27.9 0.0 1.4 1 0 0 1 1 1 1 DnaJ domain zf-C2H2 PF00096.26 KFX93954.1 - 0.082 13.4 0.0 0.082 13.4 0.0 4.5 6 0 0 6 6 6 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFX93954.1 - 0.57 11.2 0.1 0.57 11.2 0.1 5.8 6 0 0 6 6 6 0 C2H2-type zinc finger DZR PF12773.7 KFX93954.1 - 2.1 8.4 15.5 7.5 6.7 7.8 3.2 2 1 0 2 2 2 0 Double zinc ribbon zf-Di19 PF05605.12 KFX93954.1 - 2.5 8.5 19.5 0.09 13.1 1.5 4.0 2 2 1 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding Syntaxin PF00804.25 KFX93959.1 - 5.9e-22 78.3 16.0 2.7e-21 76.2 16.0 2.0 1 1 0 1 1 1 1 Syntaxin Use1 PF09753.9 KFX93959.1 - 1.3e-07 31.6 9.8 2e-07 31.0 9.8 1.4 1 0 0 1 1 1 1 Membrane fusion protein Use1 SNARE PF05739.19 KFX93959.1 - 5.1e-07 29.6 10.4 5.1e-07 29.6 10.4 3.1 2 1 0 2 2 2 1 SNARE domain Vac_Fusion PF02346.16 KFX93959.1 - 0.00038 20.0 0.4 0.055 13.1 0.0 2.8 2 0 0 2 2 2 1 Chordopoxvirus multifunctional envelope protein A27 ODV-E18 PF10717.9 KFX93959.1 - 0.018 14.9 0.1 0.043 13.7 0.1 1.6 1 0 0 1 1 1 0 Occlusion-derived virus envelope protein ODV-E18 T2SSF PF00482.23 KFX93959.1 - 0.021 14.8 4.1 0.19 11.7 3.3 2.7 1 1 1 2 2 2 0 Type II secretion system (T2SS), protein F SecG PF03840.14 KFX93959.1 - 0.029 14.4 1.4 0.09 12.9 1.4 1.8 1 0 0 1 1 1 0 Preprotein translocase SecG subunit DUF2207 PF09972.9 KFX93959.1 - 0.049 12.4 2.3 0.097 11.4 2.4 1.7 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) FUSC PF04632.12 KFX93959.1 - 0.056 12.0 5.4 0.13 10.7 5.4 1.6 1 1 0 1 1 1 0 Fusaric acid resistance protein family DUF1772 PF08592.11 KFX93959.1 - 0.09 13.1 0.0 0.18 12.1 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1772) SP_C-Propep PF08999.10 KFX93959.1 - 0.13 12.1 2.1 0.28 11.0 2.1 1.5 1 0 0 1 1 1 0 Surfactant protein C, N terminal propeptide 7tm_7 PF08395.12 KFX93959.1 - 0.16 11.2 2.1 0.53 9.4 0.0 2.1 2 0 0 2 2 2 0 7tm Chemosensory receptor PBP1_TM PF14812.6 KFX93959.1 - 0.25 11.7 2.3 1 9.7 0.0 2.6 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Chordopox_A33R PF05966.12 KFX93959.1 - 0.39 10.0 2.2 0.53 9.5 0.4 1.9 2 0 0 2 2 2 0 Chordopoxvirus A33R protein DUF4094 PF13334.6 KFX93959.1 - 0.7 10.3 8.9 1.1 9.7 4.6 3.2 1 1 2 3 3 3 0 Domain of unknown function (DUF4094) Spectrin PF00435.21 KFX93959.1 - 0.99 9.9 12.9 1.5 9.4 0.5 3.2 2 1 1 3 3 3 0 Spectrin repeat DUF1319 PF07028.11 KFX93959.1 - 1.8 8.8 9.8 1.5 9.1 1.4 2.9 2 2 1 3 3 3 0 Protein of unknown function (DUF1319) Allexi_40kDa PF05549.11 KFX93959.1 - 2.1 7.8 10.0 0.22 11.0 0.4 2.3 1 1 0 2 2 2 0 Allexivirus 40kDa protein Memo PF01875.17 KFX93961.1 - 1.5e-77 260.4 0.0 1.7e-77 260.2 0.0 1.0 1 0 0 1 1 1 1 Memo-like protein WD40 PF00400.32 KFX93962.1 - 9.6e-10 38.9 14.4 1.8 9.5 0.0 8.3 8 0 0 8 8 8 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFX93962.1 - 2.7e-07 30.8 0.5 0.091 13.1 0.0 6.1 4 2 2 6 6 6 1 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 KFX93962.1 - 0.043 13.8 0.1 0.7 9.9 0.0 2.6 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat DUF5046 PF16465.5 KFX93962.1 - 0.075 12.5 0.0 0.16 11.4 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5046) Rad4 PF03835.15 KFX93963.1 - 2.2e-14 53.4 1.1 4.5e-14 52.4 1.1 1.5 1 0 0 1 1 1 1 Rad4 transglutaminase-like domain Transglut_core PF01841.19 KFX93963.1 - 8e-13 48.8 3.6 1.7e-12 47.8 3.6 1.5 1 0 0 1 1 1 1 Transglutaminase-like superfamily YdjO PF14169.6 KFX93963.1 - 0.071 12.8 1.1 1.5 8.6 0.4 2.5 2 0 0 2 2 2 0 Cold-inducible protein YdjO Totivirus_coat PF05518.11 KFX93963.1 - 0.3 9.1 1.1 0.46 8.5 1.1 1.2 1 0 0 1 1 1 0 Totivirus coat protein DUF4462 PF14692.6 KFX93967.1 - 0.42 10.1 1.4 2.1 7.9 0.4 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4462) KH_1 PF00013.29 KFX93978.1 - 4.3e-48 161.0 15.3 1.3e-16 60.1 0.6 3.4 3 0 0 3 3 3 3 KH domain KH_2 PF07650.17 KFX93978.1 - 2.3e-11 43.4 5.0 0.0094 15.8 0.1 3.4 3 0 0 3 3 3 3 KH domain KH_4 PF13083.6 KFX93978.1 - 5.3e-09 35.8 6.0 0.041 13.8 0.1 3.4 3 0 0 3 3 3 3 KH domain KH_5 PF13184.6 KFX93978.1 - 0.00025 21.1 3.7 1.3 9.2 0.0 3.5 3 0 0 3 3 3 3 NusA-like KH domain MOEP19 PF16005.5 KFX93978.1 - 0.12 12.3 0.0 8.9 6.4 0.0 3.0 3 0 0 3 3 3 0 KH-like RNA-binding domain TIP49 PF06068.13 KFX93979.1 - 4.2e-167 555.7 0.1 5.4e-167 555.4 0.1 1.1 1 0 0 1 1 1 1 TIP49 P-loop domain TIP49_C PF17856.1 KFX93979.1 - 2.2e-23 82.2 0.1 5.3e-23 80.9 0.1 1.7 1 0 0 1 1 1 1 TIP49 AAA-lid domain AAA PF00004.29 KFX93979.1 - 8.1e-11 42.5 0.3 1.4e-06 28.8 0.1 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 KFX93979.1 - 4.4e-09 36.3 0.1 6.6e-06 25.9 0.0 2.4 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 KFX93979.1 - 2e-05 24.9 0.2 0.26 11.5 0.1 2.5 2 1 0 2 2 2 2 AAA domain AAA_5 PF07728.14 KFX93979.1 - 5e-05 23.3 0.2 0.036 14.1 0.0 2.5 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 KFX93979.1 - 6e-05 23.5 0.1 0.00072 20.0 0.1 2.2 1 1 0 1 1 1 1 AAA ATPase domain AAA_28 PF13521.6 KFX93979.1 - 0.00021 21.6 0.1 0.00048 20.4 0.1 1.6 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KFX93979.1 - 0.00027 21.3 1.6 0.06 13.7 0.1 2.4 2 1 0 2 2 2 1 AAA domain Sigma54_activat PF00158.26 KFX93979.1 - 0.00065 19.4 0.0 1 9.0 0.0 2.4 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_25 PF13481.6 KFX93979.1 - 0.00069 19.2 0.1 0.0038 16.8 0.0 2.0 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.12 KFX93979.1 - 0.0075 15.6 0.1 0.024 13.9 0.1 1.8 1 0 0 1 1 1 1 Zeta toxin Mg_chelatase PF01078.21 KFX93979.1 - 0.0087 15.5 0.1 0.5 9.7 0.0 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.17 KFX93979.1 - 0.017 14.9 0.1 0.036 13.8 0.1 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_18 PF13238.6 KFX93979.1 - 0.025 15.1 0.1 0.073 13.6 0.0 1.8 2 0 0 2 2 1 0 AAA domain DUF2075 PF09848.9 KFX93979.1 - 0.026 13.7 0.0 0.038 13.2 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) ATPase PF06745.13 KFX93979.1 - 0.027 13.8 0.2 0.13 11.6 0.0 2.0 2 0 0 2 2 2 0 KaiC AAA_14 PF13173.6 KFX93979.1 - 0.031 14.3 0.0 0.63 10.1 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 KFX93979.1 - 0.036 13.8 0.2 0.83 9.3 0.1 2.4 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 KFX93979.1 - 0.059 12.9 0.1 0.26 10.8 0.0 2.0 2 0 0 2 2 2 0 P-loop containing dynein motor region DnaB_C PF03796.15 KFX93979.1 - 0.059 12.7 0.0 0.14 11.5 0.0 1.6 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain NACHT PF05729.12 KFX93979.1 - 0.17 11.8 0.0 0.5 10.3 0.0 1.7 2 0 0 2 2 2 0 NACHT domain Sigma54_activ_2 PF14532.6 KFX93979.1 - 0.17 12.0 0.0 4 7.6 0.0 2.4 3 0 0 3 3 2 0 Sigma-54 interaction domain PhoH PF02562.16 KFX93979.1 - 0.19 11.2 1.0 1 8.8 0.1 2.5 3 0 0 3 3 3 0 PhoH-like protein HMG_box PF00505.19 KFX93980.1 - 5.9e-21 74.7 1.2 1.1e-20 73.8 1.2 1.4 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KFX93980.1 - 9.5e-07 29.3 0.3 1.7e-06 28.6 0.3 1.4 1 0 0 1 1 1 1 HMG-box domain MATalpha_HMGbox PF04769.12 KFX93980.1 - 0.0061 15.9 0.0 0.012 15.0 0.0 1.4 1 0 0 1 1 1 1 Mating-type protein MAT alpha 1 HMG-box CHDNT PF08073.12 KFX93980.1 - 0.16 11.9 0.0 0.42 10.6 0.0 1.7 1 0 0 1 1 1 0 CHDNT (NUC034) domain Glyco_hydro_63 PF03200.16 KFX93981.1 - 7.3e-09 34.9 7.3 6.8e-07 28.4 0.0 4.0 4 1 0 4 4 4 2 Glycosyl hydrolase family 63 C-terminal domain Host_attach PF10116.9 KFX93981.1 - 0.039 14.5 0.2 0.084 13.5 0.2 1.5 1 0 0 1 1 1 0 Protein required for attachment to host cells DNA_pol3_delta2 PF13177.6 KFX93982.1 - 3.6e-11 43.1 0.0 6.6e-11 42.2 0.0 1.5 1 1 0 1 1 1 1 DNA polymerase III, delta subunit AAA PF00004.29 KFX93982.1 - 1.5e-06 28.7 0.0 3.2e-06 27.6 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KFX93982.1 - 3.9e-05 24.0 0.2 0.00018 21.8 0.1 2.1 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.6 KFX93982.1 - 0.00041 20.8 0.9 0.011 16.1 0.4 2.8 2 1 0 2 2 2 1 AAA ATPase domain AAA_24 PF13479.6 KFX93982.1 - 0.0011 18.7 0.5 0.0034 17.1 0.5 1.7 1 1 0 1 1 1 1 AAA domain Rep_fac_C PF08542.11 KFX93982.1 - 0.0028 18.0 0.3 0.0097 16.3 0.0 2.0 2 0 0 2 2 2 1 Replication factor C C-terminal domain Rad17 PF03215.15 KFX93982.1 - 0.0053 16.7 0.0 0.012 15.6 0.0 1.6 2 0 0 2 2 2 1 Rad17 P-loop domain ABC_tran PF00005.27 KFX93982.1 - 0.014 15.9 0.1 0.025 15.1 0.1 1.6 1 1 0 1 1 1 0 ABC transporter T4SS-DNA_transf PF02534.14 KFX93982.1 - 0.052 12.3 0.0 0.18 10.5 0.0 1.7 2 0 0 2 2 2 0 Type IV secretory system Conjugative DNA transfer Shugoshin_N PF07558.11 KFX93983.1 - 2.7e-17 62.3 3.6 5.3e-17 61.4 3.6 1.5 1 0 0 1 1 1 1 Shugoshin N-terminal coiled-coil region Shugoshin_C PF07557.11 KFX93983.1 - 6.3e-12 45.1 4.6 6.3e-12 45.1 4.6 3.0 2 0 0 2 2 2 1 Shugoshin C terminus DASH_Dad2 PF08654.10 KFX93984.1 - 2.3e-34 117.8 0.3 3.6e-34 117.1 0.3 1.3 1 0 0 1 1 1 1 DASH complex subunit Dad2 NFACT-R_1 PF05670.13 KFX93986.1 - 2.2e-37 128.0 0.7 3.1e-37 127.6 0.1 1.5 2 0 0 2 2 2 1 NFACT protein RNA binding domain Ribosomal_L3 PF00297.22 KFX93987.1 - 6.8e-13 48.3 4.4 1.1e-09 37.8 1.8 2.3 1 1 1 2 2 2 2 Ribosomal protein L3 ABC2_membrane PF01061.24 KFX93989.1 - 1.2e-78 263.4 59.0 2.1e-43 148.2 22.8 3.5 4 0 0 4 4 4 2 ABC-2 type transporter PDR_CDR PF06422.12 KFX93989.1 - 6.9e-32 109.2 17.8 6.8e-30 102.8 0.1 3.8 4 0 0 4 4 4 2 CDR ABC transporter ABC_tran PF00005.27 KFX93989.1 - 7.8e-17 62.1 0.0 2.2e-16 60.6 0.0 1.8 2 0 0 2 2 2 1 ABC transporter ABC2_membrane_3 PF12698.7 KFX93989.1 - 2.3e-05 23.7 32.9 0.0038 16.4 10.2 3.2 2 2 1 3 3 2 2 ABC-2 family transporter protein AAA_25 PF13481.6 KFX93989.1 - 0.00026 20.6 0.1 0.0006 19.4 0.0 1.6 2 0 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 KFX93989.1 - 0.00034 20.5 0.1 0.00062 19.7 0.1 1.3 1 0 0 1 1 1 1 RsgA GTPase AAA_21 PF13304.6 KFX93989.1 - 0.00065 19.6 0.1 1.3 8.8 0.0 2.7 3 0 0 3 3 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 KFX93989.1 - 0.0035 16.8 0.0 0.096 12.1 0.0 2.2 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 KFX93989.1 - 0.0046 17.3 0.1 0.011 16.1 0.1 1.7 1 0 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.6 KFX93989.1 - 0.0048 16.6 0.2 0.012 15.4 0.2 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_33 PF13671.6 KFX93989.1 - 0.026 14.7 0.0 0.088 13.0 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 KFX93989.1 - 0.048 13.9 0.0 0.13 12.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 KFX93989.1 - 0.066 13.7 0.1 0.19 12.2 0.1 1.7 2 0 0 2 2 2 0 AAA domain Rad51 PF08423.11 KFX93989.1 - 0.095 11.9 0.1 0.15 11.3 0.1 1.2 1 0 0 1 1 1 0 Rad51 AAA_30 PF13604.6 KFX93989.1 - 0.15 11.8 0.0 0.28 10.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain cobW PF02492.19 KFX93989.1 - 0.19 11.3 0.1 0.33 10.5 0.1 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_18 PF13238.6 KFX93989.1 - 0.22 12.1 0.0 0.46 11.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain CcmH PF03918.14 KFX93989.1 - 0.29 10.4 1.3 0.55 9.5 0.0 2.1 2 0 0 2 2 2 0 Cytochrome C biogenesis protein DUF5542 PF17696.1 KFX93989.1 - 3.2 7.9 6.3 14 5.8 6.3 2.2 1 0 0 1 1 1 0 Family of unknown function (DUF5542) DUF1129 PF06570.11 KFX93989.1 - 3.7 7.0 7.6 7.1 6.1 2.4 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1129) RNase_PH PF01138.21 KFX93990.1 - 2.4e-15 57.2 0.0 5.8e-15 56.0 0.0 1.6 1 1 0 1 1 1 1 3' exoribonuclease family, domain 1 SRP-alpha_N PF04086.13 KFX93991.1 - 1.9e-82 277.5 0.0 2.6e-82 277.0 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle, alpha subunit, N-terminal SRP54 PF00448.22 KFX93991.1 - 3.2e-51 173.8 0.1 5.5e-51 173.0 0.1 1.4 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain SRP54_N PF02881.19 KFX93991.1 - 3.5e-08 33.6 0.1 1e-07 32.0 0.1 1.8 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain MeaB PF03308.16 KFX93991.1 - 1.9e-06 27.1 0.0 3.8e-06 26.1 0.0 1.4 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB CbiA PF01656.23 KFX93991.1 - 0.0014 18.7 0.1 0.012 15.7 0.0 2.4 2 1 0 2 2 2 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_30 PF13604.6 KFX93991.1 - 0.0019 18.0 0.7 0.0038 17.0 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_31 PF13614.6 KFX93991.1 - 0.0044 17.0 0.3 0.032 14.1 0.1 2.1 1 1 1 2 2 2 1 AAA domain AAA_24 PF13479.6 KFX93991.1 - 0.0053 16.5 0.0 0.011 15.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain cobW PF02492.19 KFX93991.1 - 0.0095 15.5 0.1 0.019 14.6 0.1 1.4 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain Fer4_NifH PF00142.18 KFX93991.1 - 0.014 14.9 0.0 0.023 14.2 0.0 1.3 1 0 0 1 1 1 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family NTPase_1 PF03266.15 KFX93991.1 - 0.026 14.4 0.1 0.064 13.2 0.1 1.6 1 0 0 1 1 1 0 NTPase AAA_33 PF13671.6 KFX93991.1 - 0.029 14.5 0.0 0.059 13.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 KFX93991.1 - 0.05 14.1 0.0 0.23 12.0 0.0 2.2 2 0 0 2 2 2 0 ABC transporter AAA_16 PF13191.6 KFX93991.1 - 0.052 13.9 0.0 0.19 12.1 0.0 1.9 2 0 0 2 2 2 0 AAA ATPase domain AAA_17 PF13207.6 KFX93991.1 - 0.07 13.6 0.3 0.4 11.1 0.0 2.2 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.23 KFX93991.1 - 0.088 12.9 0.6 0.52 10.4 0.6 2.2 1 1 0 1 1 1 0 50S ribosome-binding GTPase ArsA_ATPase PF02374.15 KFX93991.1 - 0.089 12.0 0.1 2.2 7.4 0.1 2.2 2 0 0 2 2 2 0 Anion-transporting ATPase AAA_15 PF13175.6 KFX93991.1 - 0.19 11.4 0.0 0.37 10.4 0.0 1.5 2 0 0 2 2 2 0 AAA ATPase domain YIF1 PF03878.15 KFX93992.1 - 4.4e-92 307.9 0.5 6.6e-92 307.4 0.5 1.2 1 0 0 1 1 1 1 YIF1 AMP-binding PF00501.28 KFX93992.1 - 7e-68 229.2 0.0 9e-68 228.8 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KFX93992.1 - 2e-06 28.7 0.0 5.7e-06 27.2 0.0 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Yip1 PF04893.17 KFX93992.1 - 0.00014 21.6 5.4 0.00038 20.2 5.4 1.6 1 0 0 1 1 1 1 Yip1 domain Aldedh PF00171.22 KFX93993.1 - 1.8e-123 412.5 0.0 2.1e-123 412.2 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family HhH-GPD PF00730.25 KFX93994.1 - 1.6e-05 25.3 0.0 3.3e-05 24.3 0.0 1.6 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein GATase_6 PF13522.6 KFX93995.1 - 1.8e-13 50.8 0.0 4.4e-13 49.6 0.0 1.7 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.6 KFX93995.1 - 3.5e-11 43.1 0.0 8e-11 41.9 0.0 1.7 1 0 0 1 1 1 1 Glutamine amidotransferase domain Pribosyltran PF00156.27 KFX93995.1 - 3.1e-08 33.3 0.0 6.7e-08 32.2 0.0 1.5 1 0 0 1 1 1 1 Phosphoribosyl transferase domain GATase_4 PF13230.6 KFX93995.1 - 0.003 16.5 0.0 0.0056 15.6 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferases class-II TFIIS_C PF01096.18 KFX93996.1 - 9.1e-20 70.2 3.1 9.1e-20 70.2 3.1 2.7 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.16 KFX93996.1 - 0.0098 15.8 13.8 0.016 15.1 0.1 3.4 3 0 0 3 3 3 2 RNA polymerases M/15 Kd subunit zf-RING_12 PF17976.1 KFX93996.1 - 9.3 6.6 8.0 0.81 10.0 0.9 2.7 3 1 0 3 3 3 0 RING/Ubox like zinc-binding domain Ank_2 PF12796.7 KFX93997.1 - 3.8e-09 37.0 0.0 6.6e-09 36.2 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KFX93997.1 - 7.8e-08 32.0 0.1 0.0028 18.0 0.0 3.9 3 1 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.6 KFX93997.1 - 5e-07 30.2 0.0 3.2e-06 27.6 0.0 2.1 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank PF00023.30 KFX93997.1 - 1.4e-06 28.5 0.0 0.076 13.5 0.0 2.7 2 0 0 2 2 2 2 Ankyrin repeat SIL1 PF16782.5 KFX93997.1 - 0.013 14.8 0.0 0.016 14.4 0.0 1.1 1 0 0 1 1 1 0 Nucleotide exchange factor SIL1 Ank_5 PF13857.6 KFX93997.1 - 0.041 14.2 0.2 2.2 8.7 0.1 3.2 2 1 1 3 3 3 0 Ankyrin repeats (many copies) Rdx PF10262.9 KFX94001.1 - 2.7e-32 110.8 0.0 4.7e-32 110.0 0.0 1.4 1 0 0 1 1 1 1 Rdx family G-gamma PF00631.22 KFX94001.1 - 5e-23 80.9 0.0 9.2e-23 80.0 0.0 1.4 1 0 0 1 1 1 1 GGL domain Glyco_hydro_31 PF01055.26 KFX94002.1 - 1e-22 81.0 0.0 1.2e-22 80.8 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 AMP-binding PF00501.28 KFX94008.1 - 1.3e-75 254.6 0.0 2.1e-75 254.0 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme NAD_binding_4 PF07993.12 KFX94008.1 - 6.8e-59 199.1 0.0 1e-58 198.5 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein PP-binding PF00550.25 KFX94008.1 - 1.2e-11 44.7 0.0 3.2e-11 43.4 0.0 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site Epimerase PF01370.21 KFX94008.1 - 2.1e-11 43.8 0.0 4.5e-11 42.7 0.0 1.6 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KFX94008.1 - 1.3e-07 30.9 0.0 6.6e-07 28.6 0.0 2.0 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 KFX94008.1 - 0.00013 21.2 0.1 0.00056 19.1 0.0 2.0 2 0 0 2 2 2 1 RmlD substrate binding domain AMP-binding_C PF13193.6 KFX94008.1 - 0.00014 22.7 0.3 0.00068 20.6 0.1 2.4 3 0 0 3 3 3 1 AMP-binding enzyme C-terminal domain ADH_N_2 PF16884.5 KFX94009.1 - 1.7e-31 108.3 0.0 3.9e-31 107.2 0.0 1.7 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase ADH_zinc_N PF00107.26 KFX94009.1 - 3.3e-21 75.6 0.0 5.8e-21 74.8 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KFX94009.1 - 5e-07 30.8 0.0 1.4e-06 29.4 0.0 1.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase DUF3425 PF11905.8 KFX94010.1 - 2.7e-19 69.3 2.1 6.7e-19 68.1 2.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) bZIP_1 PF00170.21 KFX94010.1 - 0.00014 21.9 11.5 0.0011 19.0 11.5 2.3 1 1 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 KFX94010.1 - 0.41 10.8 12.2 6.5 6.9 7.7 2.6 2 0 0 2 2 2 0 Basic region leucine zipper Latarcin PF10279.9 KFX94010.1 - 2.7 8.5 4.8 2.8 8.4 2.9 2.1 2 1 0 2 2 2 0 Latarcin precursor DUF3712 PF12505.8 KFX94012.1 - 1.9e-29 102.5 0.8 4.2e-29 101.3 0.8 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3712) DUF2236 PF09995.9 KFX94013.1 - 8.8e-30 104.6 0.2 1.2e-29 104.1 0.2 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2236) SKG6 PF08693.10 KFX94013.1 - 0.17 11.3 0.7 0.33 10.4 0.7 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain DUF3149 PF11346.8 KFX94013.1 - 0.65 9.7 3.3 1.2 8.8 3.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3149) AMP-binding PF00501.28 KFX94014.1 - 1e-74 251.7 0.0 1.3e-74 251.3 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KFX94014.1 - 8.5e-13 49.1 0.1 1.8e-12 48.1 0.1 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Glyco_hydro_114 PF03537.13 KFX94031.1 - 6.2e-81 271.1 0.2 9e-81 270.6 0.2 1.2 1 0 0 1 1 1 1 Glycoside-hydrolase family GH114 Abhydrolase_1 PF00561.20 KFX94031.1 - 4.2e-10 39.7 0.1 8.5e-09 35.4 0.1 2.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KFX94031.1 - 4e-09 37.4 0.4 9.7e-09 36.2 0.1 1.8 2 0 0 2 2 2 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KFX94031.1 - 3.1e-06 26.7 0.0 4.9e-06 26.0 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydro_lipase PF04083.16 KFX94031.1 - 0.074 12.6 0.0 0.15 11.6 0.0 1.5 1 0 0 1 1 1 0 Partial alpha/beta-hydrolase lipase region Glyco_hydro_6 PF01341.17 KFX94032.1 - 3e-96 322.8 0.5 3.8e-96 322.4 0.5 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 6 Fungal_trans PF04082.18 KFX94033.1 - 2.4e-14 53.0 0.2 4.7e-14 52.1 0.2 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KFX94033.1 - 1.9e-05 24.7 12.5 3.1e-05 24.0 12.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain LMBR1 PF04791.16 KFX94034.1 - 4.2e-18 65.6 6.7 4.2e-18 65.6 6.7 2.6 2 1 1 3 3 3 2 LMBR1-like membrane protein DUF3611 PF12263.8 KFX94034.1 - 0.13 12.2 0.1 0.13 12.2 0.1 3.3 2 1 0 3 3 3 0 Protein of unknown function (DUF3611) Anemone_cytotox PF06369.12 KFX94034.1 - 0.19 11.3 0.2 0.41 10.3 0.2 1.5 1 0 0 1 1 1 0 Sea anemone cytotoxic protein CPSF_A PF03178.15 KFX94035.1 - 1.2e-89 300.9 0.0 3.8e-89 299.2 0.0 1.8 2 0 0 2 2 2 1 CPSF A subunit region MMS1_N PF10433.9 KFX94035.1 - 2.3e-22 79.3 0.0 4.1e-22 78.5 0.0 1.3 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term Phage_holin_3_1 PF05106.12 KFX94036.1 - 0.07 13.6 0.3 0.07 13.6 0.3 2.0 2 0 0 2 2 2 0 Phage holin family (Lysis protein S) EOS1 PF12326.8 KFX94036.1 - 1.4 8.8 5.3 0.27 11.1 0.7 2.1 2 0 0 2 2 2 0 N-glycosylation protein MFS_1 PF07690.16 KFX94037.1 - 4.2e-24 85.1 38.3 6.1e-23 81.3 38.0 2.0 1 1 0 1 1 1 1 Major Facilitator Superfamily Lon_C PF05362.13 KFX94037.1 - 0.068 12.7 0.0 0.11 12.0 0.0 1.2 1 0 0 1 1 1 0 Lon protease (S16) C-terminal proteolytic domain CoatB PF10389.9 KFX94037.1 - 2.8 7.9 7.8 0.18 11.7 1.2 2.3 3 0 0 3 3 3 0 Bacteriophage coat protein B DUF347 PF03988.12 KFX94038.1 - 0.13 12.5 1.7 0.24 11.6 1.7 1.4 1 0 0 1 1 1 0 Repeat of Unknown Function (DUF347) CoatB PF10389.9 KFX94038.1 - 0.17 11.7 6.9 0.46 10.4 6.9 1.7 1 0 0 1 1 1 0 Bacteriophage coat protein B SKG6 PF08693.10 KFX94038.1 - 1 8.9 5.0 1.9 8.0 5.0 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Tho2 PF11262.8 KFX94038.1 - 6.4 5.9 7.9 1.9 7.6 2.5 2.1 2 0 0 2 2 2 0 Transcription factor/nuclear export subunit protein 2 Syntaxin-6_N PF09177.11 KFX94038.1 - 7.1 7.3 9.6 14 6.3 7.3 2.8 2 1 0 2 2 2 0 Syntaxin 6, N-terminal FlxA PF14282.6 KFX94038.1 - 8.4 6.4 10.6 0.098 12.7 1.3 2.4 3 0 0 3 3 3 0 FlxA-like protein DivIVA PF05103.13 KFX94038.1 - 9.2 6.4 17.1 11 6.1 7.8 3.2 2 1 0 2 2 2 0 DivIVA protein Pyr_redox_2 PF07992.14 KFX94039.1 - 1.8e-51 175.1 1.8 2.9e-51 174.5 1.8 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Rieske PF00355.26 KFX94039.1 - 2.1e-15 56.4 0.1 1e-14 54.2 0.0 2.1 2 0 0 2 2 2 1 Rieske [2Fe-2S] domain Pyr_redox PF00070.27 KFX94039.1 - 6e-15 55.6 2.5 2.8e-13 50.2 0.2 2.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Reductase_C PF14759.6 KFX94039.1 - 8.8e-05 23.0 0.0 0.00027 21.4 0.0 1.9 1 0 0 1 1 1 1 Reductase C-terminal K_oxygenase PF13434.6 KFX94039.1 - 0.0005 19.3 0.1 0.88 8.6 0.0 2.7 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) DUF1188 PF06690.11 KFX94039.1 - 0.00095 18.8 0.1 0.0023 17.5 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1188) Rieske_2 PF13806.6 KFX94039.1 - 0.0015 18.5 0.0 0.014 15.4 0.0 2.5 3 0 0 3 3 3 1 Rieske-like [2Fe-2S] domain NAD_binding_9 PF13454.6 KFX94039.1 - 0.0078 16.2 0.8 0.95 9.4 0.0 3.1 3 0 0 3 3 3 1 FAD-NAD(P)-binding HI0933_like PF03486.14 KFX94039.1 - 0.012 14.3 2.4 0.19 10.4 0.1 3.0 3 1 1 4 4 4 0 HI0933-like protein Trp_halogenase PF04820.14 KFX94039.1 - 0.014 14.3 0.3 0.76 8.6 0.0 2.2 2 0 0 2 2 2 0 Tryptophan halogenase FIST PF08495.10 KFX94039.1 - 0.042 13.9 0.2 0.37 10.8 0.0 2.3 2 0 0 2 2 2 0 FIST N domain TrkA_N PF02254.18 KFX94039.1 - 0.17 12.2 0.6 2 8.7 0.1 2.3 2 0 0 2 2 2 0 TrkA-N domain DUF1479 PF07350.12 KFX94041.1 - 1.1e-30 106.8 0.1 1.2e-30 106.6 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1479) Glyco_transf_28 PF03033.20 KFX94042.1 - 9e-17 61.4 0.0 2.7e-16 59.9 0.0 1.9 1 1 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain UDPGT PF00201.18 KFX94042.1 - 1.4e-06 27.4 0.0 2.5e-06 26.6 0.0 1.2 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.16 KFX94042.1 - 0.00023 21.2 0.0 0.00052 20.0 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain VPS13_C PF16909.5 KFX94042.1 - 0.034 13.9 0.1 0.092 12.5 0.1 1.7 2 0 0 2 2 2 0 Vacuolar-sorting-associated 13 protein C-terminal ATG_C PF09333.11 KFX94042.1 - 0.12 12.8 0.4 0.94 9.9 0.0 2.7 3 0 0 3 3 3 0 Autophagy-related protein C terminal domain Filament PF00038.21 KFX94043.1 - 0.00089 18.9 9.1 0.00089 18.9 9.1 3.5 1 1 2 3 3 3 2 Intermediate filament protein Tropomyosin PF00261.20 KFX94043.1 - 0.006 16.0 4.8 0.006 16.0 4.8 4.4 1 1 2 4 4 4 1 Tropomyosin TMF_TATA_bd PF12325.8 KFX94043.1 - 0.08 13.2 27.1 0.02 15.1 4.7 4.4 2 2 2 4 4 4 0 TATA element modulatory factor 1 TATA binding Pilin PF00114.19 KFX94043.1 - 0.13 13.1 0.9 0.35 11.8 0.4 2.1 2 0 0 2 2 2 0 Pilin (bacterial filament) BRE1 PF08647.11 KFX94043.1 - 0.53 10.4 31.4 0.093 12.8 4.6 4.4 3 1 0 4 4 4 0 BRE1 E3 ubiquitin ligase Fib_alpha PF08702.10 KFX94043.1 - 0.86 9.8 25.2 0.072 13.3 5.4 3.5 2 1 0 3 3 3 0 Fibrinogen alpha/beta chain family NPV_P10 PF05531.12 KFX94043.1 - 1.1 9.7 6.6 15 6.1 0.0 4.0 4 0 0 4 4 4 0 Nucleopolyhedrovirus P10 protein RYDR_ITPR PF01365.21 KFX94043.1 - 2 7.8 9.5 1.1 8.6 4.7 2.3 2 0 0 2 2 2 0 RIH domain ADIP PF11559.8 KFX94043.1 - 2.2 8.4 41.2 1.9 8.6 5.0 4.2 1 1 3 4 4 4 0 Afadin- and alpha -actinin-Binding FlaC_arch PF05377.11 KFX94043.1 - 2.2 8.7 4.0 46 4.5 0.1 3.6 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) Forkhead PF00250.18 KFX94044.1 - 4.5e-24 84.5 0.1 8.4e-24 83.7 0.1 1.4 1 0 0 1 1 1 1 Forkhead domain FHA PF00498.26 KFX94044.1 - 0.00016 22.0 0.0 0.00054 20.3 0.0 1.9 2 0 0 2 2 2 1 FHA domain DUF1765 PF08578.10 KFX94050.1 - 0.11 13.0 0.3 46 4.5 0.0 4.1 3 0 0 3 3 3 0 Protein of unknown function (DUF1765) DUF2457 PF10446.9 KFX94050.1 - 6.1 5.9 6.3 11 5.0 6.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) U3snoRNP10 PF12397.8 KFX94050.1 - 7 7.0 10.3 6.8 7.1 0.4 4.7 5 0 0 5 5 5 0 U3 small nucleolar RNA-associated protein 10 Acetyltransf_3 PF13302.7 KFX94051.1 - 6.3e-21 75.5 0.0 9.2e-21 75.0 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KFX94051.1 - 1.1e-06 28.8 0.0 1.6e-06 28.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family AhpC-TSA PF00578.21 KFX94052.1 - 6.5e-30 103.6 0.0 1.4e-29 102.5 0.0 1.5 2 0 0 2 2 2 1 AhpC/TSA family Redoxin PF08534.10 KFX94052.1 - 4.4e-21 75.2 0.0 7.1e-20 71.2 0.0 2.0 1 1 0 1 1 1 1 Redoxin AhpC-TSA_2 PF13911.6 KFX94052.1 - 0.0023 18.0 0.0 0.0068 16.5 0.0 1.8 2 1 0 2 2 2 1 AhpC/TSA antioxidant enzyme DUF899 PF05988.12 KFX94052.1 - 0.0072 15.9 0.0 0.0091 15.5 0.0 1.1 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF899) Glyco_hydro_88 PF07470.13 KFX94054.1 - 2.6e-67 227.3 0.4 3.2e-67 227.0 0.4 1.0 1 0 0 1 1 1 1 Glycosyl Hydrolase Family 88 Sugar_tr PF00083.24 KFX94055.1 - 5.7e-97 325.4 26.3 6.8e-97 325.2 26.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KFX94055.1 - 1.1e-24 87.1 68.6 7.4e-22 77.7 40.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF872 PF05915.12 KFX94055.1 - 2.2 8.5 5.7 8.5 6.6 0.1 2.6 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF872) FAD_binding_3 PF01494.19 KFX94056.1 - 1.1e-27 97.3 0.0 1.6e-27 96.7 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 KFX94056.1 - 1.2e-10 41.5 4.2 1.1e-06 28.5 1.1 2.4 1 1 1 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KFX94056.1 - 2.1e-07 31.1 0.3 4.8e-07 29.9 0.3 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KFX94056.1 - 2.2e-07 30.4 1.4 0.0013 18.1 0.4 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 KFX94056.1 - 8e-06 25.4 0.0 0.0038 16.6 0.0 2.1 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase Pyr_redox_3 PF13738.6 KFX94056.1 - 2.6e-05 23.7 0.5 0.057 12.7 0.4 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KFX94056.1 - 6e-05 21.9 0.4 0.0023 16.7 0.2 2.2 2 0 0 2 2 2 1 HI0933-like protein FAD_binding_2 PF00890.24 KFX94056.1 - 6.2e-05 22.3 0.4 0.00011 21.5 0.1 1.6 2 0 0 2 2 2 1 FAD binding domain NAD_binding_9 PF13454.6 KFX94056.1 - 0.00014 21.9 1.6 0.12 12.3 0.0 3.5 4 0 0 4 4 4 1 FAD-NAD(P)-binding Lycopene_cycl PF05834.12 KFX94056.1 - 0.00019 20.6 1.7 0.0027 16.8 1.4 2.3 2 1 0 2 2 2 1 Lycopene cyclase protein Pyr_redox PF00070.27 KFX94056.1 - 0.0007 20.1 0.4 2 9.0 0.1 2.6 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KFX94056.1 - 0.00098 18.4 0.1 0.0021 17.4 0.1 1.5 1 0 0 1 1 1 1 Thi4 family GIDA PF01134.22 KFX94056.1 - 0.0033 16.6 0.6 0.007 15.5 0.3 1.6 2 0 0 2 2 2 1 Glucose inhibited division protein A Trp_halogenase PF04820.14 KFX94056.1 - 0.0058 15.5 0.6 0.74 8.6 0.1 2.9 3 0 0 3 3 3 1 Tryptophan halogenase ApbA PF02558.16 KFX94056.1 - 0.012 15.3 0.2 0.021 14.5 0.2 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA UDPG_MGDP_dh_N PF03721.14 KFX94056.1 - 0.15 11.7 0.0 0.25 10.9 0.0 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Glyco_hydro_43 PF04616.14 KFX94057.1 - 1.3e-37 129.7 4.5 1.8e-37 129.2 4.5 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 GH43_C2 PF17851.1 KFX94057.1 - 2.5e-25 89.4 0.2 4.2e-25 88.7 0.2 1.4 1 0 0 1 1 1 1 Beta xylosidase C-terminal Concanavalin A-like domain LPMO_10 PF03067.15 KFX94058.1 - 0.068 13.8 0.6 0.14 12.8 0.1 1.8 2 0 0 2 2 2 0 Lytic polysaccharide mono-oxygenase, cellulose-degrading DUF1304 PF06993.12 KFX94064.1 - 4.6e-44 148.9 4.4 5.2e-44 148.7 4.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1304) Ank_2 PF12796.7 KFX94065.1 - 2.4e-16 60.1 0.0 3.1e-08 34.1 0.0 2.3 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KFX94065.1 - 5.6e-11 41.7 0.0 0.074 13.6 0.0 4.6 4 0 0 4 4 4 3 Ankyrin repeat Ank_4 PF13637.6 KFX94065.1 - 4.8e-10 39.8 0.0 0.0001 22.8 0.0 2.5 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 KFX94065.1 - 3.2e-09 36.8 0.1 0.0034 17.8 0.0 4.3 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.6 KFX94065.1 - 7.4e-07 29.3 0.1 0.0089 16.3 0.0 2.8 1 1 2 3 3 3 3 Ankyrin repeats (many copies) HET PF06985.11 KFX94066.1 - 2.4e-10 41.0 1.4 6.7e-07 29.8 0.1 2.4 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) FB_lectin PF07367.11 KFX94066.1 - 0.018 15.0 0.1 0.064 13.2 0.1 1.8 2 0 0 2 2 2 0 Fungal fruit body lectin ANAPC8 PF04049.13 KFX94069.1 - 2.7e-35 121.4 0.0 6.1e-35 120.3 0.0 1.6 1 0 0 1 1 1 1 Anaphase promoting complex subunit 8 / Cdc23 TPR_1 PF00515.28 KFX94069.1 - 2.4e-22 77.8 1.1 0.00011 21.8 0.0 6.9 7 0 0 7 7 7 5 Tetratricopeptide repeat TPR_8 PF13181.6 KFX94069.1 - 3.8e-17 61.0 3.5 0.0049 17.0 0.0 6.7 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_2 PF07719.17 KFX94069.1 - 5.7e-16 57.3 7.5 0.0045 17.0 0.0 7.5 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_14 PF13428.6 KFX94069.1 - 1.1e-15 57.0 20.0 0.01 16.6 0.2 9.6 7 2 3 10 10 10 4 Tetratricopeptide repeat TPR_19 PF14559.6 KFX94069.1 - 2.7e-08 34.2 5.9 0.023 15.2 0.0 6.3 8 0 0 8 8 6 2 Tetratricopeptide repeat TPR_11 PF13414.6 KFX94069.1 - 5.8e-07 29.1 0.5 0.17 11.6 0.0 4.8 4 1 1 5 5 5 2 TPR repeat TPR_12 PF13424.6 KFX94069.1 - 6.8e-07 29.5 14.3 0.47 10.8 0.1 7.1 6 1 1 7 7 7 3 Tetratricopeptide repeat TPR_7 PF13176.6 KFX94069.1 - 3.5e-06 26.6 10.9 0.049 13.7 0.2 6.2 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_17 PF13431.6 KFX94069.1 - 7.5e-06 26.0 0.9 51 4.6 0.0 6.4 6 0 0 6 6 6 0 Tetratricopeptide repeat ANAPC3 PF12895.7 KFX94069.1 - 8e-05 22.8 12.9 2 8.7 1.0 6.4 6 1 1 7 7 6 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.6 KFX94069.1 - 0.0021 18.2 12.2 0.31 11.2 0.0 5.5 5 1 1 6 6 5 1 Tetratricopeptide repeat TPR_15 PF13429.6 KFX94069.1 - 0.01 15.1 1.0 0.052 12.8 0.1 2.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_10 PF13374.6 KFX94069.1 - 0.012 15.5 9.6 11 6.0 0.0 5.0 5 0 0 5 5 5 0 Tetratricopeptide repeat DUF3856 PF12968.7 KFX94069.1 - 0.018 15.1 1.5 0.42 10.7 0.1 3.0 1 1 2 3 3 3 0 Domain of Unknown Function (DUF3856) TPR_16 PF13432.6 KFX94069.1 - 0.018 15.7 14.6 0.067 13.9 1.2 5.5 4 1 0 5 5 5 0 Tetratricopeptide repeat Sel1 PF08238.12 KFX94069.1 - 0.03 15.0 0.6 2.3 9.0 0.1 3.5 3 0 0 3 3 3 0 Sel1 repeat TPR_6 PF13174.6 KFX94069.1 - 0.094 13.4 8.6 11 6.9 0.1 5.9 7 0 0 7 7 5 0 Tetratricopeptide repeat TPR_3 PF07720.12 KFX94069.1 - 0.18 11.8 1.4 36 4.5 0.0 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat Ank_2 PF12796.7 KFX94071.1 - 7.5e-25 87.3 4.4 7e-08 33.0 0.2 4.3 2 1 1 4 4 4 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KFX94071.1 - 3.9e-23 81.5 0.6 4.3e-06 27.2 0.0 5.1 2 1 3 5 5 5 5 Ankyrin repeats (many copies) Ank_5 PF13857.6 KFX94071.1 - 1.8e-20 72.7 4.5 2.4e-07 30.9 0.1 5.9 3 2 4 7 7 7 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFX94071.1 - 1.4e-18 65.1 4.9 0.014 15.8 0.0 8.2 9 0 0 9 9 7 5 Ankyrin repeat Ank PF00023.30 KFX94071.1 - 3.6e-12 46.1 7.4 0.087 13.3 0.0 7.0 7 0 0 7 7 7 3 Ankyrin repeat NACHT PF05729.12 KFX94071.1 - 4.5e-08 33.2 0.0 3.6e-07 30.2 0.0 2.4 2 0 0 2 2 2 1 NACHT domain Helo_like_N PF17111.5 KFX94071.1 - 2.4e-07 30.3 6.3 3.2e-07 29.9 1.6 2.5 2 1 0 2 2 2 1 Fungal N-terminal domain of STAND proteins AAA_16 PF13191.6 KFX94071.1 - 4.4e-05 23.9 0.0 0.00015 22.2 0.0 1.9 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 KFX94071.1 - 0.022 15.0 0.0 0.08 13.2 0.0 1.9 1 0 0 1 1 1 0 AAA domain DUF5407 PF17401.2 KFX94071.1 - 0.12 12.6 0.1 0.34 11.2 0.1 1.8 1 0 0 1 1 1 0 Family of unknown function (DUF5407) SesA PF17107.5 KFX94071.1 - 2 8.6 7.3 0.2 11.9 0.8 2.6 3 0 0 3 3 3 0 N-terminal domain on NACHT_NTPase and P-loop NTPases Carn_acyltransf PF00755.20 KFX94073.1 - 1.4e-100 337.7 0.0 1.9e-100 337.2 0.0 1.2 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase ketoacyl-synt PF00109.26 KFX94073.1 - 4.5e-76 255.8 0.0 1.2e-75 254.4 0.0 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain PS-DH PF14765.6 KFX94073.1 - 6.3e-58 196.4 0.1 1.1e-57 195.6 0.1 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase Acyl_transf_1 PF00698.21 KFX94073.1 - 2.2e-50 172.0 1.6 3.8e-50 171.2 1.6 1.4 1 0 0 1 1 1 1 Acyl transferase domain KR PF08659.10 KFX94073.1 - 3.8e-45 154.0 0.2 3.8e-45 154.0 0.2 1.9 2 0 0 2 2 2 1 KR domain Ketoacyl-synt_C PF02801.22 KFX94073.1 - 1.3e-38 131.6 0.3 5e-38 129.7 0.3 2.1 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain ADH_zinc_N_2 PF13602.6 KFX94073.1 - 9e-18 65.6 0.0 7.4e-15 56.2 0.0 3.1 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 KFX94073.1 - 1.6e-17 63.7 4.4 2.6e-17 63.0 0.4 3.3 4 0 0 4 4 3 1 Zinc-binding dehydrogenase Methyltransf_12 PF08242.12 KFX94073.1 - 5.2e-16 59.2 0.0 2.4e-15 57.0 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain KAsynt_C_assoc PF16197.5 KFX94073.1 - 7.2e-15 55.4 0.1 4.1e-14 53.0 0.1 2.4 1 1 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension Methyltransf_23 PF13489.6 KFX94073.1 - 1.9e-12 47.3 0.0 6.3e-12 45.6 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain adh_short PF00106.25 KFX94073.1 - 2.8e-12 46.5 3.2 9.8e-12 44.7 0.1 2.7 2 0 0 2 2 2 1 short chain dehydrogenase Methyltransf_25 PF13649.6 KFX94073.1 - 1.9e-11 44.5 0.0 1.5e-10 41.6 0.0 2.7 2 0 0 2 2 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KFX94073.1 - 1.6e-09 37.5 0.0 5.3e-09 35.7 0.0 1.9 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_11 PF08241.12 KFX94073.1 - 8.6e-09 35.9 0.0 4.5e-08 33.6 0.0 2.4 1 0 0 1 1 1 1 Methyltransferase domain PP-binding PF00550.25 KFX94073.1 - 1.2e-07 31.9 0.2 3.3e-07 30.6 0.2 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site adh_short_C2 PF13561.6 KFX94073.1 - 4.5e-07 29.7 0.7 2.1e-06 27.5 0.1 2.4 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase Methyltransf_31 PF13847.6 KFX94073.1 - 2e-06 27.6 0.0 2.8e-05 23.9 0.0 2.6 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_16 PF10294.9 KFX94073.1 - 0.00076 19.2 0.0 0.0023 17.7 0.0 1.8 1 0 0 1 1 1 1 Lysine methyltransferase ACP_syn_III PF08545.10 KFX94073.1 - 0.011 15.6 0.0 0.53 10.2 0.0 2.9 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III DREV PF05219.12 KFX94073.1 - 0.018 14.2 0.0 0.046 12.8 0.0 1.6 1 0 0 1 1 1 0 DREV methyltransferase Thiolase_N PF00108.23 KFX94073.1 - 0.054 12.8 2.4 0.24 10.7 0.0 2.7 2 0 0 2 2 2 0 Thiolase, N-terminal domain PCMT PF01135.19 KFX94073.1 - 0.9 9.2 3.0 4.1 7.1 0.0 3.2 3 0 0 3 3 3 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Glyco_trans_2_3 PF13632.6 KFX94074.1 - 5.2e-24 85.3 2.8 5.2e-24 85.3 2.8 2.0 2 0 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 KFX94074.1 - 1.6e-14 54.4 0.0 2.3e-14 53.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 MFS_1 PF07690.16 KFX94075.1 - 1.1e-39 136.4 36.4 1.1e-39 136.4 36.4 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF4064 PF13273.6 KFX94075.1 - 0.089 13.1 0.4 0.089 13.1 0.4 3.8 5 1 1 6 6 6 0 Protein of unknown function (DUF4064) OATP PF03137.20 KFX94075.1 - 0.11 10.7 10.9 0.3 9.3 9.3 2.3 1 1 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family HlyD_D23 PF16576.5 KFX94077.1 - 0.15 11.3 3.2 0.2 10.9 3.2 1.1 1 0 0 1 1 1 0 Barrel-sandwich domain of CusB or HlyD membrane-fusion Trypan_PARP PF05887.11 KFX94077.1 - 0.31 11.0 18.8 0.34 10.9 17.0 1.9 1 1 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Cellulase PF00150.18 KFX94078.1 - 5.8e-45 153.9 0.0 7.5e-45 153.5 0.0 1.0 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_7 PF00840.20 KFX94079.1 - 8.2e-74 248.9 0.0 9.4e-74 248.7 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 7 Cellulase PF00150.18 KFX94080.1 - 1.6e-49 168.8 0.4 1.9e-49 168.6 0.4 1.0 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) AMP-binding PF00501.28 KFX94081.1 - 1.1e-62 212.1 0.0 1.4e-62 211.7 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme Condensation PF00668.20 KFX94081.1 - 2e-22 79.5 0.0 4.7e-22 78.3 0.0 1.6 1 1 0 1 1 1 1 Condensation domain AMP-binding_C PF13193.6 KFX94081.1 - 1.2e-08 35.7 0.2 3.3e-08 34.4 0.2 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain GH3 PF03321.13 KFX94081.1 - 0.0015 17.5 0.0 0.0085 15.0 0.0 1.9 2 0 0 2 2 2 1 GH3 auxin-responsive promoter DUF2867 PF11066.8 KFX94082.1 - 6.5e-34 117.3 0.0 8.2e-34 117.0 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2867) Ank_5 PF13857.6 KFX94090.1 - 0.061 13.7 0.0 0.083 13.2 0.0 1.2 1 0 0 1 1 1 0 Ankyrin repeats (many copies) Ank PF00023.30 KFX94090.1 - 0.18 12.3 0.5 0.31 11.5 0.5 1.6 1 1 0 1 1 1 0 Ankyrin repeat zf-HC3 PF16827.5 KFX94091.1 - 0.12 12.5 0.3 0.3 11.3 0.1 1.7 2 0 0 2 2 2 0 zinc-finger Rad60-SLD PF11976.8 KFX94102.1 - 8.6e-17 60.7 0.0 1.2e-16 60.2 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 KFX94102.1 - 0.0024 17.6 0.0 0.0056 16.4 0.0 1.6 1 1 0 1 1 1 1 Ubiquitin family MOSC_N PF03476.16 KFX94102.1 - 0.032 14.1 0.0 0.043 13.7 0.0 1.2 1 0 0 1 1 1 0 MOSC N-terminal beta barrel domain GATase_4 PF13230.6 KFX94104.1 - 3.3e-13 49.2 0.0 2.4e-11 43.0 0.0 2.1 2 0 0 2 2 2 2 Glutamine amidotransferases class-II GATase_6 PF13522.6 KFX94104.1 - 6.7e-08 32.8 0.0 1.5e-07 31.6 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain Cation_efflux PF01545.21 KFX94105.1 - 1.1e-12 48.2 16.4 1.4e-12 47.8 16.4 1.1 1 0 0 1 1 1 1 Cation efflux family PNRC PF15365.6 KFX94105.1 - 8 6.4 11.7 4.5 7.2 1.4 3.9 3 0 0 3 3 3 0 Proline-rich nuclear receptor coactivator motif PIG-Y PF15159.6 KFX94106.1 - 4e-23 82.1 8.2 6e-23 81.5 8.2 1.3 1 0 0 1 1 1 1 Phosphatidylinositol N-acetylglucosaminyltransferase subunit Y DUF1218 PF06749.12 KFX94106.1 - 0.041 14.4 3.1 0.85 10.2 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1218) DUF2956 PF11169.8 KFX94106.1 - 3.8 7.7 5.4 1.9 8.7 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2956) Ebp2 PF05890.12 KFX94108.1 - 8.5e-52 176.3 31.4 9.5e-52 176.2 31.4 1.0 1 0 0 1 1 1 1 Eukaryotic rRNA processing protein EBP2 Ecm29 PF13001.7 KFX94109.1 - 4.1e-164 546.9 0.3 5.4e-163 543.2 0.0 2.7 3 0 0 3 3 3 1 Proteasome stabiliser HEAT PF02985.22 KFX94109.1 - 1.8e-06 27.7 2.6 7.4 7.1 0.0 7.7 8 0 0 8 8 8 2 HEAT repeat HEAT_EZ PF13513.6 KFX94109.1 - 9.1e-05 22.9 10.7 0.72 10.4 0.1 8.8 8 2 1 9 9 9 1 HEAT-like repeat HEAT_2 PF13646.6 KFX94109.1 - 0.0011 19.3 12.7 0.67 10.4 0.2 8.3 8 1 0 8 8 8 1 HEAT repeats Vac14_Fab1_bd PF12755.7 KFX94109.1 - 0.0012 19.4 0.1 0.19 12.3 0.0 4.5 4 1 0 4 4 4 1 Vacuolar 14 Fab1-binding region TAN PF11640.8 KFX94109.1 - 0.025 14.7 0.6 13 5.9 0.0 3.9 3 0 0 3 3 3 0 Telomere-length maintenance and DNA damage repair HD_assoc PF13286.6 KFX94109.1 - 0.098 13.2 0.0 30 5.2 0.0 3.8 3 0 0 3 3 3 0 Phosphohydrolase-associated domain IFRD PF05004.13 KFX94109.1 - 0.26 10.4 12.5 3.8 6.5 0.1 5.6 5 1 0 6 6 6 0 Interferon-related developmental regulator (IFRD) CRAL_TRIO PF00650.20 KFX94121.1 - 3.4e-36 124.4 0.0 5e-36 123.8 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 KFX94121.1 - 8.6e-07 29.0 0.0 1.8e-06 28.0 0.0 1.6 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.6 KFX94121.1 - 0.00039 20.6 0.0 0.00091 19.4 0.0 1.5 2 0 0 2 2 2 1 Divergent CRAL/TRIO domain Prefoldin PF02996.17 KFX94122.1 - 6.8e-32 109.9 0.1 1.4e-31 108.9 0.0 1.5 2 0 0 2 2 2 1 Prefoldin subunit Prefoldin_2 PF01920.20 KFX94122.1 - 0.0062 16.5 0.7 0.085 12.8 0.0 2.4 2 1 0 2 2 2 1 Prefoldin subunit Syntaxin-6_N PF09177.11 KFX94122.1 - 0.0096 16.5 0.6 4.3 7.9 0.0 2.2 2 0 0 2 2 2 2 Syntaxin 6, N-terminal THOC7 PF05615.13 KFX94122.1 - 0.038 14.3 0.5 0.36 11.1 0.0 2.1 2 0 0 2 2 2 0 Tho complex subunit 7 SlyX PF04102.12 KFX94122.1 - 0.044 14.4 0.5 4.7 7.9 0.1 2.6 3 0 0 3 3 3 0 SlyX End3 PF12761.7 KFX94122.1 - 0.073 13.2 0.4 0.26 11.5 0.0 1.9 2 0 0 2 2 2 0 Actin cytoskeleton-regulatory complex protein END3 DUF4795 PF16043.5 KFX94122.1 - 0.13 11.9 1.7 2.8 7.5 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4795) DUF3112 PF11309.8 KFX94123.1 - 2.8e-11 43.3 9.5 6.7e-06 25.7 0.1 2.5 2 1 1 3 3 3 2 Protein of unknown function (DUF3112) YwiC PF14256.6 KFX94123.1 - 0.55 10.5 12.0 3.7 7.9 1.0 2.6 2 1 0 2 2 2 0 YwiC-like protein Zn_clus PF00172.18 KFX94124.1 - 1.2e-06 28.6 9.6 2.1e-06 27.7 9.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MCM_OB PF17207.3 KFX94124.1 - 0.17 11.8 5.7 0.1 12.4 3.0 1.9 2 0 0 2 2 2 0 MCM OB domain Abhydrolase_6 PF12697.7 KFX94125.1 - 3.2e-12 47.5 0.1 4.2e-12 47.2 0.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Pkinase PF00069.25 KFX94137.1 - 3.9e-54 183.8 0.0 5.6e-54 183.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFX94137.1 - 6.3e-30 104.3 0.0 1.1e-28 100.3 0.0 2.1 2 0 0 2 2 2 1 Protein tyrosine kinase Haspin_kinase PF12330.8 KFX94137.1 - 0.0092 15.0 0.0 0.015 14.3 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Pox_ser-thr_kin PF05445.11 KFX94137.1 - 0.086 11.8 0.0 0.12 11.3 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Kdo PF06293.14 KFX94137.1 - 0.1 11.9 0.1 0.19 11.1 0.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Cro PF09048.10 KFX94137.1 - 0.14 12.3 0.1 5.4 7.1 0.0 2.5 2 0 0 2 2 2 0 Cro Kelch_5 PF13854.6 KFX94138.1 - 1.7e-05 24.7 0.0 1.7e-05 24.7 0.0 2.9 3 0 0 3 3 3 1 Kelch motif Glyco_hydro_62 PF03664.13 KFX94139.1 - 4.1e-156 518.3 16.6 5.9e-156 517.8 16.6 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 62 CBM_1 PF00734.18 KFX94139.1 - 1.4e-10 40.9 17.4 5.1e-10 39.1 17.4 2.1 1 0 0 1 1 1 1 Fungal cellulose binding domain Phage_Mu_Gam PF07352.12 KFX94139.1 - 0.065 13.1 14.7 0.11 12.4 14.7 1.3 1 0 0 1 1 1 0 Bacteriophage Mu Gam like protein HC2 PF07382.11 KFX94139.1 - 0.15 12.2 21.6 0.31 11.1 21.6 1.5 1 0 0 1 1 1 0 Histone H1-like nucleoprotein HC2 Cas_DxTHG PF09455.10 KFX94139.1 - 0.68 9.5 4.2 1 8.9 4.2 1.2 1 0 0 1 1 1 0 CRISPR-associated (Cas) DxTHG family HlyD_2 PF12700.7 KFX94139.1 - 4 6.1 8.0 5.8 5.5 8.0 1.1 1 0 0 1 1 1 0 HlyD family secretion protein GrpE PF01025.19 KFX94139.1 - 6.3 6.4 17.4 11 5.6 17.4 1.3 1 0 0 1 1 1 0 GrpE V_ATPase_I PF01496.19 KFX94139.1 - 8.7 4.1 6.0 12 3.6 6.0 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Kelch_4 PF13418.6 KFX94142.1 - 5.1e-27 93.6 11.3 2.9e-07 30.4 0.0 6.2 6 1 0 6 6 6 5 Galactose oxidase, central domain Kelch_3 PF13415.6 KFX94142.1 - 2.7e-24 84.9 16.3 3.2e-07 30.5 0.2 6.2 7 0 0 7 7 7 4 Galactose oxidase, central domain Kelch_6 PF13964.6 KFX94142.1 - 1.1e-17 63.7 2.1 0.00028 21.1 0.1 6.0 6 0 0 6 6 6 3 Kelch motif Kelch_5 PF13854.6 KFX94142.1 - 2.9e-16 59.1 2.9 1.3e-06 28.2 0.0 6.4 6 0 0 6 6 6 3 Kelch motif DUF4110 PF13422.6 KFX94142.1 - 8.8e-16 57.8 0.1 8.8e-16 57.8 0.1 2.9 3 0 0 3 3 3 1 Domain of unknown function (DUF4110) Kelch_1 PF01344.25 KFX94142.1 - 2.5e-15 55.8 0.6 3.9e-05 23.1 0.0 5.6 5 1 0 5 5 5 3 Kelch motif Kelch_2 PF07646.15 KFX94142.1 - 6.4e-12 45.0 2.7 0.19 11.8 0.0 6.3 6 1 0 6 6 6 3 Kelch motif MCPVI PF02993.14 KFX94142.1 - 0.054 13.3 1.4 0.13 12.1 1.4 1.6 1 0 0 1 1 1 0 Minor capsid protein VI Jak1_Phl PF17887.1 KFX94142.1 - 2.2 8.2 10.4 0.069 13.1 3.9 1.7 2 0 0 2 2 2 0 Jak1 pleckstrin homology-like domain Abhydrolase_1 PF00561.20 KFX94143.1 - 2.2e-11 43.9 0.0 3.7e-11 43.2 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KFX94143.1 - 1.7e-07 30.8 0.0 4e-07 29.6 0.0 1.6 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 KFX94143.1 - 0.029 13.9 0.0 0.29 10.6 0.0 2.1 1 1 0 1 1 1 0 Prolyl oligopeptidase family CENP-K PF11802.8 KFX94144.1 - 1.7e-06 27.8 7.3 0.0045 16.6 0.0 3.1 2 1 0 2 2 2 2 Centromere-associated protein K FlgN PF05130.12 KFX94144.1 - 0.11 13.0 12.5 0.36 11.3 0.9 2.9 3 0 0 3 3 3 0 FlgN protein Spc7 PF08317.11 KFX94144.1 - 0.5 9.2 8.2 1.4 7.7 1.6 2.2 2 0 0 2 2 2 0 Spc7 kinetochore protein Fib_alpha PF08702.10 KFX94144.1 - 1.2 9.3 4.5 9.6 6.4 0.5 2.5 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family BAR PF03114.18 KFX94144.1 - 1.4 8.5 9.7 4.6 6.8 5.3 2.9 2 1 0 2 2 2 0 BAR domain DUF4446 PF14584.6 KFX94144.1 - 1.5 8.8 5.4 2.8 7.9 0.3 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF4446) Macoilin PF09726.9 KFX94144.1 - 1.7 7.1 7.3 5.5 5.4 7.3 1.7 1 1 0 1 1 1 0 Macoilin family APH PF01636.23 KFX94151.1 - 5.4e-09 36.3 0.0 8.3e-09 35.7 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KFX94151.1 - 6.2e-06 26.0 0.0 1e-05 25.3 0.0 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase DUF1679 PF07914.11 KFX94151.1 - 0.026 13.4 0.0 0.035 13.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) GMC_oxred_C PF05199.13 KFX94152.1 - 4.6e-30 105.0 0.0 7.7e-30 104.3 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_N PF00732.19 KFX94152.1 - 9.5e-26 90.8 0.0 9.9e-25 87.5 0.0 2.4 1 1 0 2 2 2 1 GMC oxidoreductase Pyr_redox_2 PF07992.14 KFX94152.1 - 5.7e-05 22.5 0.0 0.0033 16.7 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KFX94152.1 - 0.0034 16.7 0.0 0.67 9.1 0.0 2.6 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KFX94152.1 - 0.0042 17.3 0.0 0.011 16.0 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 KFX94152.1 - 0.12 11.4 1.1 0.39 9.8 0.4 1.9 2 0 0 2 2 2 0 FAD binding domain 3HCDH_N PF02737.18 KFX94152.1 - 0.14 12.1 0.0 0.53 10.2 0.0 1.9 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DAO PF01266.24 KFX94152.1 - 0.15 11.6 0.8 20 4.6 0.0 2.6 3 0 0 3 3 3 0 FAD dependent oxidoreductase CFEM PF05730.11 KFX94153.1 - 6.4e-14 51.8 8.8 1.2e-13 50.9 8.8 1.4 1 0 0 1 1 1 1 CFEM domain DUF2759 PF10958.8 KFX94153.1 - 0.077 12.7 4.5 3.7 7.3 0.3 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF2759) Phage_holin_3_6 PF07332.11 KFX94153.1 - 7.7 6.6 6.5 3.2 7.8 0.3 2.8 3 0 0 3 3 3 0 Putative Actinobacterial Holin-X, holin superfamily III Peroxidase_2 PF01328.17 KFX94154.1 - 6e-44 150.8 0.0 7.7e-44 150.5 0.0 1.1 1 0 0 1 1 1 1 Peroxidase, family 2 Pkinase PF00069.25 KFX94155.1 - 4.4e-28 98.4 0.0 6.4e-28 97.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFX94155.1 - 8.6e-19 67.8 0.0 1.4e-18 67.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase BTRD1 PF17660.1 KFX94156.1 - 0.063 13.1 0.1 0.15 11.9 0.0 1.7 2 0 0 2 2 2 0 Bacterial tandem repeat domain 1 HABP4_PAI-RBP1 PF04774.15 KFX94159.1 - 0.092 13.6 3.0 0.22 12.4 3.0 1.9 1 1 0 1 1 1 0 Hyaluronan / mRNA binding family adh_short_C2 PF13561.6 KFX94160.1 - 8.8e-44 149.8 0.2 1.1e-43 149.5 0.2 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KFX94160.1 - 2e-39 135.1 0.1 2.4e-39 134.8 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KFX94160.1 - 7.4e-13 48.8 0.3 1e-12 48.3 0.3 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KFX94160.1 - 0.064 12.7 0.9 0.42 10.0 0.9 2.2 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 KFX94160.1 - 0.064 12.4 0.1 0.088 11.9 0.1 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein F-box-like PF12937.7 KFX94161.1 - 1.3e-05 25.0 0.0 3.3e-05 23.7 0.0 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KFX94161.1 - 0.0018 18.1 0.3 0.006 16.4 0.3 1.9 1 0 0 1 1 1 1 F-box domain Peptidase_S10 PF00450.22 KFX94162.1 - 8.5e-113 377.9 0.0 1e-112 377.6 0.0 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase RNA_Me_trans PF04252.13 KFX94163.1 - 5.6e-82 274.2 0.0 6.3e-82 274.0 0.0 1.0 1 0 0 1 1 1 1 Predicted SAM-dependent RNA methyltransferase SMG1_N PF17229.2 KFX94164.1 - 0.19 12.5 0.0 0.19 12.5 0.0 1.2 1 0 0 1 1 1 0 Serine/threonine-protein kinase SMG1 N-terminal Sde2_N_Ubi PF13019.6 KFX94170.1 - 3.6e-69 231.8 0.7 6.9e-69 230.9 0.7 1.5 1 0 0 1 1 1 1 Silencing defective 2 N-terminal ubiquitin domain S10_plectin PF03501.15 KFX94171.1 - 8.4e-29 99.5 0.1 1.2e-28 99.0 0.1 1.1 1 0 0 1 1 1 1 Plectin/S10 domain Ribosomal_L15e PF00827.17 KFX94172.1 - 8.5e-89 296.4 7.3 2e-88 295.1 7.3 1.6 1 0 0 1 1 1 1 Ribosomal L15 zf-HIT PF04438.16 KFX94173.1 - 2.2e-09 37.0 10.0 3.4e-09 36.4 10.0 1.3 1 0 0 1 1 1 1 HIT zinc finger zf-MYND PF01753.18 KFX94173.1 - 0.0065 16.5 9.5 0.011 15.8 9.5 1.3 1 0 0 1 1 1 1 MYND finger zf-B_box PF00643.24 KFX94173.1 - 0.15 12.3 6.2 0.24 11.6 6.2 1.3 1 0 0 1 1 1 0 B-box zinc finger C1_2 PF03107.16 KFX94173.1 - 0.21 11.9 3.8 0.37 11.2 3.8 1.3 1 0 0 1 1 1 0 C1 domain GTP_EFTU PF00009.27 KFX94190.1 - 1.1e-53 181.7 0.0 1.8e-53 181.0 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 KFX94190.1 - 2.2e-42 143.9 0.0 4.6e-42 142.9 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 KFX94190.1 - 3.6e-13 49.7 2.9 3.6e-13 49.7 2.9 2.1 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 KFX94190.1 - 0.00071 19.6 0.1 0.016 15.2 0.1 2.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase zf-MIZ PF02891.20 KFX94191.1 - 8.8e-11 41.4 0.3 1.7e-10 40.5 0.3 1.5 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger PINIT PF14324.6 KFX94191.1 - 0.00042 20.7 0.0 0.0013 19.0 0.0 1.9 1 0 0 1 1 1 1 PINIT domain zf-Nse PF11789.8 KFX94191.1 - 0.0041 16.9 0.2 0.021 14.7 0.1 2.3 2 0 0 2 2 2 1 Zinc-finger of the MIZ type in Nse subunit LexA_DNA_bind PF01726.16 KFX94191.1 - 0.024 14.4 0.0 4 7.3 0.0 2.7 2 0 0 2 2 2 0 LexA DNA binding domain Methyltransf_16 PF10294.9 KFX94192.1 - 2e-23 83.0 0.0 2e-21 76.5 0.0 2.9 3 0 0 3 3 3 1 Lysine methyltransferase PrmA PF06325.13 KFX94192.1 - 0.00072 19.0 0.0 0.0011 18.4 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_23 PF13489.6 KFX94192.1 - 0.00074 19.4 0.0 0.0017 18.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 KFX94192.1 - 0.0057 16.4 0.0 0.022 14.5 0.0 1.8 2 0 0 2 2 2 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MTS PF05175.14 KFX94192.1 - 0.053 13.1 0.1 0.29 10.7 0.0 1.8 1 1 1 2 2 2 0 Methyltransferase small domain Methyltransf_25 PF13649.6 KFX94192.1 - 0.11 13.2 0.0 0.28 11.9 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.6 KFX94192.1 - 0.14 11.9 0.1 6.1 6.6 0.1 2.8 3 0 0 3 3 3 0 Methyltransferase domain DUF4368 PF14287.6 KFX94192.1 - 0.14 12.4 0.0 22 5.4 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4368) Ribosomal_S24e PF01282.19 KFX94193.1 - 3.6e-34 116.5 0.1 7.6e-34 115.5 0.0 1.5 1 1 0 1 1 1 1 Ribosomal protein S24e Zn_clus PF00172.18 KFX94194.1 - 3.5e-07 30.2 6.9 6e-07 29.5 6.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pro_isomerase PF00160.21 KFX94195.1 - 9.1e-35 120.3 0.0 1.4e-34 119.7 0.0 1.3 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD RRM_1 PF00076.22 KFX94195.1 - 2.9e-15 55.8 0.0 5.4e-15 55.0 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KFX94195.1 - 0.11 12.1 0.0 0.19 11.3 0.0 1.3 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TFB6 PF17110.5 KFX94196.1 - 3.9e-31 108.1 3.5 4.4e-31 107.9 3.5 1.0 1 0 0 1 1 1 1 Subunit 11 of the general transcription factor TFIIH Pes-10 PF07149.11 KFX94196.1 - 0.12 11.4 5.0 0.13 11.3 5.0 1.0 1 0 0 1 1 1 0 Pes-10 DNA_pol_phi PF04931.13 KFX94196.1 - 5 5.1 6.2 5.7 4.9 6.2 1.0 1 0 0 1 1 1 0 DNA polymerase phi Methyltransf_34 PF11312.8 KFX94203.1 - 1.3e-46 159.3 0.0 1.7e-46 158.9 0.0 1.1 1 0 0 1 1 1 1 Putative SAM-dependent methyltransferase NOP19 PF10863.8 KFX94203.1 - 0.16 11.8 0.0 0.29 11.0 0.0 1.3 1 0 0 1 1 1 0 Nucleolar protein 19 Alpha_L_fucos PF01120.17 KFX94204.1 - 1.9e-29 103.2 0.0 2.8e-28 99.4 0.0 2.0 2 0 0 2 2 2 2 Alpha-L-fucosidase Nop16 PF09420.10 KFX94205.1 - 2.6e-69 233.5 11.6 2.9e-69 233.3 11.6 1.0 1 0 0 1 1 1 1 Ribosome biogenesis protein Nop16 Mito_carr PF00153.27 KFX94207.1 - 3.8e-52 174.2 1.0 5.2e-17 61.6 0.1 3.4 3 0 0 3 3 3 3 Mitochondrial carrier protein Fungal_trans PF04082.18 KFX94207.1 - 2.4e-34 118.6 0.2 6.1e-34 117.3 0.2 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KFX94207.1 - 1.4e-05 25.2 9.1 1.4e-05 25.2 9.1 1.8 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain adh_short PF00106.25 KFX94208.1 - 8.7e-50 168.9 0.2 1.1e-49 168.5 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KFX94208.1 - 3.4e-33 115.1 0.2 4.2e-33 114.9 0.2 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KFX94208.1 - 3.6e-11 43.3 0.1 4.6e-11 43.0 0.1 1.2 1 0 0 1 1 1 1 KR domain Sacchrp_dh_NADP PF03435.18 KFX94208.1 - 0.00096 19.4 0.1 0.0017 18.6 0.1 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Polysacc_synt_2 PF02719.15 KFX94208.1 - 0.006 15.7 0.1 0.012 14.8 0.1 1.6 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein DHDPS PF00701.22 KFX94209.1 - 1e-41 142.6 0.0 1.2e-41 142.3 0.0 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family TPR_10 PF13374.6 KFX94209.1 - 0.063 13.2 0.2 1.1 9.2 0.2 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat MFS_1 PF07690.16 KFX94210.1 - 7.8e-37 127.0 33.6 2.5e-36 125.4 34.5 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily MR_MLE_C PF13378.6 KFX94211.1 - 6e-48 163.3 0.1 8e-48 162.9 0.1 1.2 1 0 0 1 1 1 1 Enolase C-terminal domain-like MR_MLE_N PF02746.16 KFX94211.1 - 0.00054 20.1 0.2 0.0025 18.0 0.2 2.1 1 1 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain DUF3218 PF11508.8 KFX94211.1 - 0.095 12.2 0.0 0.2 11.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3218) PRK PF00485.18 KFX94212.1 - 6e-06 26.1 0.0 9.2e-06 25.5 0.0 1.3 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family SRP54 PF00448.22 KFX94212.1 - 6.4e-06 25.9 0.0 8.8e-06 25.5 0.0 1.2 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain AAA_18 PF13238.6 KFX94212.1 - 0.0038 17.8 0.0 0.0082 16.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain cobW PF02492.19 KFX94212.1 - 0.01 15.5 0.0 0.013 15.1 0.0 1.2 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain TsaE PF02367.17 KFX94212.1 - 0.011 15.7 0.0 0.026 14.5 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE NACHT PF05729.12 KFX94212.1 - 0.023 14.6 0.0 0.042 13.8 0.0 1.4 1 0 0 1 1 1 0 NACHT domain KAP_NTPase PF07693.14 KFX94212.1 - 0.025 13.8 0.0 0.031 13.5 0.0 1.2 1 0 0 1 1 1 0 KAP family P-loop domain AAA_29 PF13555.6 KFX94212.1 - 0.03 14.1 0.0 0.06 13.1 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_16 PF13191.6 KFX94212.1 - 0.034 14.5 0.1 0.047 14.1 0.1 1.7 1 1 0 1 1 1 0 AAA ATPase domain MeaB PF03308.16 KFX94212.1 - 0.036 13.1 0.0 0.056 12.4 0.0 1.2 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_30 PF13604.6 KFX94212.1 - 0.037 13.8 0.0 0.084 12.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 KFX94212.1 - 0.037 14.5 0.0 0.058 13.9 0.0 1.4 1 0 0 1 1 1 0 ABC transporter AAA_28 PF13521.6 KFX94212.1 - 0.044 14.0 0.0 0.081 13.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA PF00004.29 KFX94212.1 - 0.049 14.1 0.0 0.075 13.5 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Thymidylate_kin PF02223.17 KFX94212.1 - 0.049 13.3 0.0 0.12 12.0 0.0 1.6 1 0 0 1 1 1 0 Thymidylate kinase ATP_bind_1 PF03029.17 KFX94212.1 - 0.061 13.1 0.0 0.099 12.4 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein AAA_22 PF13401.6 KFX94212.1 - 0.069 13.4 0.0 0.12 12.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 KFX94212.1 - 0.1 12.7 0.0 0.2 11.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain MobB PF03205.14 KFX94212.1 - 0.14 12.1 0.1 0.34 10.8 0.1 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_5 PF07728.14 KFX94212.1 - 0.15 12.1 0.0 0.56 10.2 0.0 1.9 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_14 PF13173.6 KFX94212.1 - 0.17 11.9 0.0 0.33 11.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain dNK PF01712.19 KFX94212.1 - 0.2 11.5 0.0 0.57 10.0 0.0 1.7 2 0 0 2 2 2 0 Deoxynucleoside kinase NDUF_B4 PF07225.12 KFX94213.1 - 0.013 15.4 0.1 0.014 15.2 0.1 1.1 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase B15 subunit (NDUFB4) Hexokinase_2 PF03727.16 KFX94231.1 - 3.9e-16 59.2 0.2 3.9e-16 59.2 0.2 1.0 1 0 0 1 1 1 1 Hexokinase GAF_2 PF13185.6 KFX94238.1 - 9.4e-09 35.7 0.0 1.6e-08 34.9 0.0 1.4 1 0 0 1 1 1 1 GAF domain GAF PF01590.26 KFX94238.1 - 3.4e-05 24.5 0.2 7.1e-05 23.4 0.0 1.6 2 0 0 2 2 2 1 GAF domain DLH PF01738.18 KFX94239.1 - 2.7e-23 82.7 0.0 1.4e-22 80.3 0.0 1.9 1 1 0 1 1 1 1 Dienelactone hydrolase family Peptidase_S9 PF00326.21 KFX94239.1 - 0.023 14.2 0.0 0.13 11.7 0.0 2.1 2 0 0 2 2 2 0 Prolyl oligopeptidase family EphA2_TM PF14575.6 KFX94240.1 - 0.0054 17.6 0.0 0.021 15.7 0.0 2.1 2 0 0 2 2 2 1 Ephrin type-A receptor 2 transmembrane domain DAP10 PF07213.11 KFX94240.1 - 0.0071 16.3 0.7 0.02 14.8 0.7 1.7 1 0 0 1 1 1 1 DAP10 membrane protein CFEM PF05730.11 KFX94240.1 - 0.019 15.0 5.9 0.042 14.0 5.9 1.5 1 0 0 1 1 1 0 CFEM domain CcmD PF04995.14 KFX94240.1 - 0.049 13.7 0.8 0.087 12.9 0.8 1.3 1 0 0 1 1 1 0 Heme exporter protein D (CcmD) TMEM154 PF15102.6 KFX94240.1 - 0.2 11.6 6.6 1.3 9.0 6.6 2.2 1 1 0 1 1 1 0 TMEM154 protein family Pkinase PF00069.25 KFX94242.1 - 3.9e-65 219.8 0.0 4.8e-65 219.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFX94242.1 - 3e-25 89.0 0.0 3.9e-25 88.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KFX94242.1 - 4.9e-07 29.4 0.0 2.4e-06 27.1 0.0 1.9 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 KFX94242.1 - 0.0021 18.0 0.0 0.0077 16.2 0.0 1.8 2 1 1 3 3 3 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KFX94242.1 - 0.1 12.1 0.0 0.16 11.6 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase Kdo PF06293.14 KFX94242.1 - 0.12 11.7 0.0 0.21 10.9 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 KFX94242.1 - 0.14 11.8 0.0 0.24 11.0 0.0 1.5 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 PLA2_B PF01735.18 KFX94243.1 - 1.4e-23 83.1 0.0 4.5e-23 81.4 0.0 1.8 1 1 0 1 1 1 1 Lysophospholipase catalytic domain Ank_3 PF13606.6 KFX94246.1 - 4.3e-08 32.8 0.1 1.2 9.9 0.0 6.4 7 0 0 7 7 7 2 Ankyrin repeat Ank_4 PF13637.6 KFX94246.1 - 2.2e-07 31.3 0.1 0.0049 17.4 0.0 4.8 3 1 2 5 5 5 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 KFX94246.1 - 2.9e-07 31.0 0.0 0.00068 20.2 0.0 3.4 2 1 0 3 3 3 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KFX94246.1 - 0.0046 17.2 0.0 7.6 7.0 0.0 3.6 3 0 0 3 3 3 2 Ankyrin repeats (many copies) MFS_1 PF07690.16 KFX94247.1 - 5.7e-28 97.9 40.7 1.9e-27 96.2 40.8 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 KFX94247.1 - 1.1e-19 70.3 16.6 1.7e-19 69.7 16.6 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 KFX94247.1 - 4.1e-16 58.9 10.6 4.1e-16 58.9 10.6 2.2 2 1 0 2 2 2 1 Sugar (and other) transporter OATP PF03137.20 KFX94247.1 - 0.022 13.1 4.4 0.1 10.9 1.5 2.3 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family DUF3522 PF12036.8 KFX94247.1 - 0.042 14.1 3.8 0.074 13.3 0.2 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF3522) DUF5326 PF17260.2 KFX94247.1 - 0.084 13.0 3.7 1.9 8.7 0.4 2.9 2 0 0 2 2 2 0 Family of unknown function (DUF5326) Glyco_hydro_10 PF00331.20 KFX94248.1 - 9e-65 218.9 3.3 4.2e-53 180.5 0.9 3.0 1 1 1 2 2 2 2 Glycosyl hydrolase family 10 ADH_zinc_N_2 PF13602.6 KFX94248.1 - 6.8e-09 36.9 0.1 1.6e-08 35.7 0.1 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase DUF1944 PF09175.10 KFX94248.1 - 0.0059 16.5 0.0 0.01 15.7 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1944) Beta-prism_lec PF16458.5 KFX94248.1 - 0.015 15.3 0.2 0.032 14.2 0.2 1.5 1 0 0 1 1 1 0 Beta-prism lectin Glyco_hydro_11 PF00457.17 KFX94249.1 - 5.5e-61 205.3 18.9 9.1e-61 204.6 18.9 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 11 MFS_1 PF07690.16 KFX94249.1 - 1.1e-15 57.4 50.1 1.7e-09 37.1 17.9 2.7 1 1 1 2 2 2 2 Major Facilitator Superfamily Ecm29 PF13001.7 KFX94249.1 - 0.055 12.1 0.0 0.079 11.6 0.0 1.1 1 0 0 1 1 1 0 Proteasome stabiliser Cyclin_N PF00134.23 KFX94250.1 - 0.0062 16.3 0.0 0.022 14.5 0.0 1.8 1 1 0 1 1 1 1 Cyclin, N-terminal domain MTES_1575 PF18741.1 KFX94250.1 - 0.091 12.9 0.1 0.16 12.2 0.1 1.3 1 0 0 1 1 1 0 REase_MTES_1575 DAO PF01266.24 KFX94251.1 - 1.4e-38 133.4 0.0 1.6e-38 133.2 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KFX94251.1 - 1.8e-06 28.1 0.0 7.4e-06 26.1 0.0 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KFX94251.1 - 1.2e-05 24.7 0.0 0.036 13.3 0.0 2.9 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KFX94251.1 - 0.00021 20.5 0.0 0.12 11.4 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain FAD_binding_3 PF01494.19 KFX94251.1 - 0.00055 19.3 0.0 0.00083 18.7 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain TrkA_N PF02254.18 KFX94251.1 - 0.0014 18.9 0.0 0.0031 17.8 0.0 1.6 1 0 0 1 1 1 1 TrkA-N domain Pyr_redox_3 PF13738.6 KFX94251.1 - 0.0039 16.5 0.0 0.018 14.3 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KFX94251.1 - 0.006 16.6 0.0 0.12 12.3 0.0 2.4 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox PF00070.27 KFX94251.1 - 0.0067 17.0 0.0 0.017 15.7 0.0 1.7 2 0 0 2 2 1 1 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.20 KFX94251.1 - 0.013 15.6 0.0 0.024 14.7 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase GIDA PF01134.22 KFX94251.1 - 0.016 14.3 0.0 0.083 12.0 0.0 1.9 2 0 0 2 2 2 0 Glucose inhibited division protein A ApbA PF02558.16 KFX94251.1 - 0.062 12.9 0.0 0.1 12.2 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA HI0933_like PF03486.14 KFX94251.1 - 0.11 11.2 0.0 12 4.5 0.0 2.1 2 0 0 2 2 2 0 HI0933-like protein Thi4 PF01946.17 KFX94251.1 - 0.12 11.6 0.0 0.22 10.7 0.0 1.4 1 0 0 1 1 1 0 Thi4 family ThiF PF00899.21 KFX94251.1 - 0.14 11.5 0.0 0.25 10.6 0.0 1.3 1 0 0 1 1 1 0 ThiF family Epimerase PF01370.21 KFX94251.1 - 0.19 11.1 0.0 0.36 10.2 0.0 1.4 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 KFX94252.1 - 1.4e-28 99.8 0.0 3.1e-28 98.6 0.0 1.6 2 0 0 2 2 2 1 Male sterility protein AMP-binding PF00501.28 KFX94252.1 - 4.8e-20 71.6 0.0 7.6e-20 70.9 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme Epimerase PF01370.21 KFX94252.1 - 4.7e-08 32.8 0.0 8.3e-08 32.0 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.25 KFX94252.1 - 1.7e-06 28.3 0.0 8.8e-06 26.0 0.0 2.3 2 0 0 2 2 2 1 Phosphopantetheine attachment site KR PF08659.10 KFX94252.1 - 0.082 12.8 0.0 0.29 11.0 0.0 2.0 1 0 0 1 1 1 0 KR domain Semialdhyde_dh PF01118.24 KFX94252.1 - 0.17 12.3 0.0 0.41 11.1 0.0 1.7 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain NmrA PF05368.13 KFX94253.1 - 2.2e-26 92.9 0.2 2.8e-26 92.5 0.2 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KFX94253.1 - 1.5e-22 80.4 0.0 3e-22 79.4 0.0 1.6 1 0 0 1 1 1 1 NAD(P)H-binding Sacchrp_dh_NADP PF03435.18 KFX94253.1 - 8e-05 22.9 0.3 0.0002 21.6 0.1 1.9 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain Epimerase PF01370.21 KFX94253.1 - 0.00094 18.7 0.1 0.0028 17.1 0.0 1.9 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family THF_DHG_CYH_C PF02882.19 KFX94253.1 - 0.0099 15.2 0.4 0.13 11.6 0.4 2.2 1 1 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain 3Beta_HSD PF01073.19 KFX94253.1 - 0.023 13.7 0.2 0.066 12.2 0.1 1.9 2 1 0 2 2 2 0 3-beta hydroxysteroid dehydrogenase/isomerase family DapB_N PF01113.20 KFX94253.1 - 0.031 14.4 0.1 0.09 12.9 0.1 1.9 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus NAD_binding_4 PF07993.12 KFX94253.1 - 0.034 13.3 0.1 0.15 11.2 0.0 1.8 2 0 0 2 2 2 0 Male sterility protein Semialdhyde_dh PF01118.24 KFX94253.1 - 0.037 14.4 1.3 0.076 13.5 0.2 1.9 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain Aldedh PF00171.22 KFX94258.1 - 1.8e-93 313.6 2.5 2.1e-93 313.4 2.5 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family AAA_7 PF12775.7 KFX94258.1 - 0.19 11.2 0.2 0.33 10.4 0.2 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region Lipl32 PF12103.8 KFX94273.1 - 0.13 11.9 0.2 0.23 11.1 0.1 1.5 2 0 0 2 2 2 0 Surface lipoprotein of Spirochaetales order DpnD-PcfM PF14207.6 KFX94274.1 - 0.71 9.8 2.9 6.7 6.7 0.2 2.3 2 0 0 2 2 2 0 DpnD/PcfM-like protein p450 PF00067.22 KFX94275.1 - 5.9e-57 193.4 0.0 8.7e-57 192.9 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 Fungal_trans PF04082.18 KFX94275.1 - 7.9e-14 51.3 0.0 1.8e-13 50.2 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KFX94275.1 - 1.3e-08 34.8 10.6 2.7e-08 33.8 10.6 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain FAA_hydrolase PF01557.18 KFX94276.1 - 6.3e-53 179.7 0.0 8.3e-53 179.3 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family FAA_hydrolase_N PF09298.11 KFX94276.1 - 4.2e-33 113.7 0.0 7.9e-33 112.8 0.0 1.5 1 0 0 1 1 1 1 Fumarylacetoacetase N-terminal Methyltransf_16 PF10294.9 KFX94277.1 - 7e-41 139.8 0.0 1.1e-40 139.2 0.0 1.2 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_25 PF13649.6 KFX94277.1 - 4.6e-06 27.2 0.0 1.6e-05 25.5 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain PrmA PF06325.13 KFX94277.1 - 9e-06 25.3 0.0 1.4e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 KFX94277.1 - 0.00019 21.0 0.0 0.00049 19.7 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_23 PF13489.6 KFX94277.1 - 0.0014 18.5 0.0 0.0021 17.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KFX94277.1 - 0.006 17.3 0.0 0.013 16.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KFX94277.1 - 0.0071 17.0 0.0 0.024 15.3 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_3 PF01596.17 KFX94277.1 - 0.021 14.0 0.0 0.035 13.3 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase DUF938 PF06080.12 KFX94277.1 - 0.16 11.7 0.0 0.26 11.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF938) Cys_Met_Meta_PP PF01053.20 KFX94279.1 - 4e-149 496.3 0.0 4.6e-149 496.1 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.21 KFX94279.1 - 2.6e-11 43.3 0.1 4.7e-11 42.5 0.1 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.17 KFX94279.1 - 8.8e-09 35.1 0.2 1.7e-08 34.2 0.2 1.4 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_5 PF00266.19 KFX94279.1 - 2.3e-07 30.1 0.1 5.5e-07 28.9 0.1 1.5 1 1 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 KFX94279.1 - 0.00063 19.1 0.0 0.0013 18.1 0.0 1.5 1 1 0 1 1 1 1 Beta-eliminating lyase Met_gamma_lyase PF06838.11 KFX94279.1 - 0.01 14.4 0.2 0.014 14.0 0.2 1.3 1 1 0 1 1 1 0 Methionine gamma-lyase GDC-P PF02347.16 KFX94279.1 - 0.017 14.0 0.0 0.025 13.4 0.0 1.2 1 0 0 1 1 1 0 Glycine cleavage system P-protein Asparaginase_C PF17763.1 KFX94279.1 - 0.019 15.2 0.1 0.055 13.7 0.0 1.8 2 0 0 2 2 2 0 Glutaminase/Asparaginase C-terminal domain MccV PF17508.2 KFX94279.1 - 0.87 10.2 5.3 0.67 10.5 0.2 2.7 3 0 0 3 3 3 0 Microcin V bacteriocin zf-C2H2_jaz PF12171.8 KFX94293.1 - 6.6e-10 39.0 8.1 0.11 12.8 0.2 5.0 5 0 0 5 5 5 4 Zinc-finger double-stranded RNA-binding zf-C2H2 PF00096.26 KFX94293.1 - 0.00016 21.9 11.5 0.00091 19.6 3.7 6.8 7 0 0 7 7 7 3 Zinc finger, C2H2 type zf-met PF12874.7 KFX94293.1 - 0.00018 21.8 12.7 0.82 10.1 0.1 5.3 6 0 0 6 6 6 3 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.6 KFX94293.1 - 0.0016 19.1 42.2 0.037 14.9 0.7 6.7 7 0 0 7 7 7 3 C2H2-type zinc finger zf-C2H2_6 PF13912.6 KFX94293.1 - 0.012 15.5 14.0 0.014 15.4 0.6 4.1 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C6H2 PF15801.5 KFX94293.1 - 0.23 11.8 3.5 5.9 7.3 0.1 3.0 2 0 0 2 2 2 0 zf-MYND-like zinc finger, mRNA-binding FOXP-CC PF16159.5 KFX94293.1 - 0.3 11.7 22.5 14 6.4 1.9 6.4 3 2 3 6 6 6 0 FOXP coiled-coil domain zf-DNA_Pol PF08996.10 KFX94293.1 - 5 6.8 13.0 0.095 12.4 2.4 2.4 2 0 0 2 2 2 0 DNA Polymerase alpha zinc finger zf-TAZ PF02135.16 KFX94293.1 - 9.5 6.8 11.5 0.69 10.4 1.0 3.4 3 0 0 3 3 3 0 TAZ zinc finger DJ-1_PfpI PF01965.24 KFX94294.1 - 1.2e-13 51.2 0.0 1.6e-13 50.8 0.0 1.3 1 0 0 1 1 1 1 DJ-1/PfpI family TPR_12 PF13424.6 KFX94297.1 - 0.0073 16.6 1.6 28 5.1 0.2 4.7 4 2 1 5 5 5 3 Tetratricopeptide repeat TPR_2 PF07719.17 KFX94297.1 - 0.32 11.2 5.7 19 5.7 0.2 5.3 6 0 0 6 6 6 0 Tetratricopeptide repeat Cyt-b5 PF00173.28 KFX94298.1 - 6.5e-05 23.0 0.1 7.5e-05 22.8 0.1 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Melibiase_2 PF16499.5 KFX94307.1 - 2.3e-62 210.7 0.7 3.5e-62 210.2 0.7 1.3 1 0 0 1 1 1 1 Alpha galactosidase A Ricin_B_lectin PF00652.22 KFX94307.1 - 2e-18 66.9 0.4 3.2e-18 66.2 0.4 1.3 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain Melibiase_C PF17801.1 KFX94307.1 - 2.4e-15 56.4 0.4 6.2e-15 55.0 0.0 1.9 2 0 0 2 2 2 1 Alpha galactosidase C-terminal beta sandwich domain Melibiase PF02065.18 KFX94307.1 - 4.4e-05 22.6 0.3 7.8e-05 21.8 0.3 1.3 1 0 0 1 1 1 1 Melibiase RicinB_lectin_2 PF14200.6 KFX94307.1 - 0.00031 21.4 1.4 0.0039 17.9 0.6 3.1 1 1 2 3 3 3 3 Ricin-type beta-trefoil lectin domain-like CDtoxinA PF03498.14 KFX94307.1 - 0.019 14.6 2.0 3.2 7.3 0.2 2.8 1 1 1 2 2 2 0 Cytolethal distending toxin A/C domain Glyco_transf_8 PF01501.20 KFX94308.1 - 5.8e-05 22.8 1.0 0.00014 21.5 0.7 1.8 2 1 0 2 2 2 1 Glycosyl transferase family 8 RNase_H PF00075.24 KFX94309.1 - 2.9e-22 79.4 0.0 4.7e-22 78.7 0.0 1.2 1 0 0 1 1 1 1 RNase H Esterase_phd PF10503.9 KFX94310.1 - 1.4e-21 77.0 0.7 1.9e-21 76.6 0.7 1.1 1 0 0 1 1 1 1 Esterase PHB depolymerase Peptidase_S9 PF00326.21 KFX94310.1 - 1.9e-12 47.2 0.5 3.3e-12 46.3 0.2 1.5 2 0 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_2 PF02230.16 KFX94310.1 - 7.3e-05 22.7 0.3 0.034 14.0 0.2 2.4 2 0 0 2 2 2 2 Phospholipase/Carboxylesterase Esterase PF00756.20 KFX94310.1 - 0.00059 19.5 0.6 0.0052 16.5 0.6 2.0 1 1 0 1 1 1 1 Putative esterase FSH1 PF03959.13 KFX94310.1 - 0.00085 19.0 0.0 0.0012 18.6 0.0 1.3 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_6 PF12697.7 KFX94310.1 - 0.0026 18.4 0.7 0.0055 17.3 0.7 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.13 KFX94310.1 - 0.0036 17.2 0.1 0.005 16.7 0.1 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KFX94310.1 - 0.0094 15.2 0.3 0.61 9.3 0.1 2.4 3 0 0 3 3 3 1 Serine aminopeptidase, S33 DUF2920 PF11144.8 KFX94310.1 - 0.069 12.3 0.0 0.11 11.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2920) AXE1 PF05448.12 KFX94310.1 - 0.16 10.6 0.1 0.31 9.7 0.0 1.4 2 0 0 2 2 2 0 Acetyl xylan esterase (AXE1) Abhydrolase_1 PF00561.20 KFX94310.1 - 0.16 11.5 2.1 0.84 9.2 0.8 2.3 1 1 1 2 2 2 0 alpha/beta hydrolase fold DLH PF01738.18 KFX94310.1 - 0.19 11.2 0.4 0.71 9.4 0.4 1.8 1 1 0 1 1 1 0 Dienelactone hydrolase family MR_MLE_C PF13378.6 KFX94311.1 - 3.8e-60 203.2 0.2 5.3e-60 202.7 0.2 1.2 1 0 0 1 1 1 1 Enolase C-terminal domain-like MR_MLE_N PF02746.16 KFX94311.1 - 8.2e-20 71.2 0.0 1.7e-19 70.1 0.0 1.5 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain SBP56 PF05694.11 KFX94312.1 - 8.7e-08 31.4 0.0 3.6e-06 26.1 0.0 2.8 1 1 0 1 1 1 1 56kDa selenium binding protein (SBP56) Lactonase PF10282.9 KFX94312.1 - 0.015 14.6 0.1 1.7 7.9 0.1 2.6 2 1 0 2 2 2 0 Lactonase, 7-bladed beta-propeller SGL PF08450.12 KFX94312.1 - 0.068 12.7 0.0 4 6.9 0.0 2.8 3 0 0 3 3 3 0 SMP-30/Gluconolactonase/LRE-like region NHL PF01436.21 KFX94312.1 - 0.075 13.1 0.2 6.9 6.9 0.0 3.1 3 0 0 3 3 3 0 NHL repeat Cupin_1 PF00190.22 KFX94313.1 - 1.8e-38 131.5 0.0 5e-19 68.4 0.0 2.1 2 0 0 2 2 2 2 Cupin Cupin_2 PF07883.11 KFX94313.1 - 4e-23 80.9 1.1 1.6e-11 43.8 0.1 2.4 2 0 0 2 2 2 2 Cupin domain Cupin_3 PF05899.12 KFX94313.1 - 1.8e-07 30.7 0.1 0.022 14.4 0.0 2.7 3 0 0 3 3 3 2 Protein of unknown function (DUF861) AraC_binding PF02311.19 KFX94313.1 - 1.8e-05 24.7 0.3 0.049 13.5 0.1 2.3 2 0 0 2 2 2 2 AraC-like ligand binding domain Cupin_6 PF12852.7 KFX94313.1 - 5.8e-05 22.9 0.1 0.69 9.6 0.0 2.9 2 1 1 3 3 3 2 Cupin 3-HAO PF06052.12 KFX94313.1 - 0.0024 17.5 0.0 1.5 8.4 0.0 2.6 3 0 0 3 3 3 2 3-hydroxyanthranilic acid dioxygenase Cupin_7 PF12973.7 KFX94313.1 - 0.017 15.1 0.2 2.6 8.0 0.1 2.6 2 0 0 2 2 2 0 ChrR Cupin-like domain p450 PF00067.22 KFX94315.1 - 3.9e-75 253.4 0.0 4.8e-75 253.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 fn3_6 PF17766.1 KFX94315.1 - 0.052 13.7 0.0 0.54 10.5 0.0 2.2 2 0 0 2 2 2 0 Fibronectin type-III domain Peptidase_M26_C PF07580.14 KFX94315.1 - 0.16 10.4 0.1 0.23 9.9 0.1 1.1 1 0 0 1 1 1 0 M26 IgA1-specific Metallo-endopeptidase C-terminal region Methyltransf_11 PF08241.12 KFX94316.1 - 2.4e-23 82.6 0.0 4e-23 81.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KFX94316.1 - 3.5e-22 78.9 0.0 6e-22 78.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KFX94316.1 - 5.6e-22 78.2 0.0 7.7e-22 77.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KFX94316.1 - 3e-16 59.5 0.0 1.2e-15 57.5 0.0 1.8 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 KFX94316.1 - 5.2e-14 52.8 0.0 8.4e-14 52.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KFX94316.1 - 2.8e-13 50.0 0.0 5e-13 49.2 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KFX94316.1 - 2.6e-09 36.9 0.0 4.3e-09 36.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain PCMT PF01135.19 KFX94316.1 - 9.5e-08 32.0 0.0 2.3e-07 30.8 0.0 1.6 2 0 0 2 2 2 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltr_RsmB-F PF01189.17 KFX94316.1 - 2.1e-06 27.5 0.0 5.4e-06 26.2 0.0 1.6 2 0 0 2 2 2 1 16S rRNA methyltransferase RsmB/F CMAS PF02353.20 KFX94316.1 - 2.6e-06 26.9 0.0 3.6e-06 26.5 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase MetW PF07021.12 KFX94316.1 - 8.3e-06 25.5 0.0 1.6e-05 24.6 0.0 1.4 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_24 PF13578.6 KFX94316.1 - 0.00015 22.7 0.0 0.00033 21.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Fibrillarin PF01269.17 KFX94316.1 - 0.00053 19.2 0.0 0.00075 18.7 0.0 1.3 1 0 0 1 1 1 1 Fibrillarin Methyltransf_29 PF03141.16 KFX94316.1 - 0.0019 16.9 0.0 0.0025 16.4 0.0 1.1 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_4 PF02390.17 KFX94316.1 - 0.0055 16.2 0.0 0.06 12.8 0.0 2.5 1 1 1 2 2 2 1 Putative methyltransferase PrmA PF06325.13 KFX94316.1 - 0.0068 15.8 0.2 0.014 14.8 0.0 1.5 2 0 0 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) GCD14 PF08704.10 KFX94316.1 - 0.0089 15.7 0.0 0.013 15.1 0.0 1.3 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit ADH_zinc_N PF00107.26 KFX94316.1 - 0.0099 15.9 0.0 0.021 14.8 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase FtsJ PF01728.19 KFX94316.1 - 0.022 14.9 0.0 0.031 14.4 0.0 1.3 1 0 0 1 1 1 0 FtsJ-like methyltransferase Methyltransf_9 PF08003.11 KFX94316.1 - 0.033 13.1 0.0 0.057 12.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) Methyltransf_32 PF13679.6 KFX94316.1 - 0.039 13.9 0.0 0.08 12.9 0.0 1.5 2 0 0 2 2 2 0 Methyltransferase domain DOT1 PF08123.13 KFX94316.1 - 0.063 12.8 0.0 1.4 8.4 0.0 2.1 1 1 1 2 2 2 0 Histone methylation protein DOT1 Methyltransf_8 PF05148.15 KFX94316.1 - 0.079 12.8 0.1 0.31 10.8 0.1 1.8 1 1 0 1 1 1 0 Hypothetical methyltransferase RrnaAD PF00398.20 KFX94316.1 - 0.12 11.4 0.0 0.2 10.7 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Octopine_DH PF02317.17 KFX94317.1 - 8.3e-39 133.1 0.0 1.3e-38 132.4 0.0 1.2 1 0 0 1 1 1 1 NAD/NADP octopine/nopaline dehydrogenase, alpha-helical domain NAD_Gly3P_dh_N PF01210.23 KFX94317.1 - 1.1e-07 32.0 0.0 1.6e-07 31.4 0.0 1.3 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus F420_oxidored PF03807.17 KFX94317.1 - 4.5e-05 24.0 0.0 9e-05 23.0 0.0 1.5 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Pyr_redox_2 PF07992.14 KFX94317.1 - 0.0015 17.9 0.0 0.0019 17.5 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 KFX94317.1 - 0.0029 16.7 0.0 0.0045 16.1 0.0 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A NAD_binding_8 PF13450.6 KFX94317.1 - 0.0031 17.7 0.1 0.013 15.7 0.1 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.19 KFX94317.1 - 0.0053 16.0 0.0 0.0075 15.6 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 KFX94317.1 - 0.0074 15.0 0.0 0.015 14.0 0.0 1.5 1 0 0 1 1 1 1 HI0933-like protein ApbA PF02558.16 KFX94317.1 - 0.017 14.8 0.0 0.029 14.0 0.0 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Lycopene_cycl PF05834.12 KFX94317.1 - 0.024 13.7 0.0 0.034 13.2 0.0 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein FAD_binding_2 PF00890.24 KFX94317.1 - 0.061 12.4 0.0 0.084 11.9 0.0 1.1 1 0 0 1 1 1 0 FAD binding domain 2-Hacid_dh_C PF02826.19 KFX94317.1 - 0.092 12.1 0.0 1 8.7 0.0 2.2 1 1 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Pyr_redox_3 PF13738.6 KFX94317.1 - 0.15 11.3 0.0 0.21 10.8 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Rossmann-like PF10727.9 KFX94317.1 - 0.17 11.7 0.2 0.99 9.3 0.2 2.1 1 1 0 1 1 1 0 Rossmann-like domain MFS_1 PF07690.16 KFX94318.1 - 8.6e-48 163.0 36.4 8.6e-48 163.0 36.4 2.7 3 0 0 3 3 3 1 Major Facilitator Superfamily Ferric_reduct PF01794.19 KFX94318.1 - 1.4e-18 67.3 12.3 1.4e-18 67.3 12.3 2.6 3 0 0 3 3 3 1 Ferric reductase like transmembrane component Sugar_tr PF00083.24 KFX94318.1 - 8.4e-14 51.3 17.2 8.4e-14 51.3 17.2 2.8 4 0 0 4 4 4 1 Sugar (and other) transporter FAD_binding_8 PF08022.12 KFX94318.1 - 4.8e-11 42.7 0.0 4e-05 23.7 0.0 2.7 3 0 0 3 3 3 2 FAD-binding domain MFS_3 PF05977.13 KFX94318.1 - 0.0004 18.9 1.7 0.0004 18.9 1.7 1.8 2 0 0 2 2 2 1 Transmembrane secretion effector NAD_binding_6 PF08030.12 KFX94318.1 - 0.0011 19.1 0.0 0.0021 18.2 0.0 1.4 1 0 0 1 1 1 1 Ferric reductase NAD binding domain Peptidase_M24 PF00557.24 KFX94319.1 - 5.4e-34 117.7 0.3 7.7e-34 117.2 0.3 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 PGA2 PF07543.12 KFX94319.1 - 0.066 13.2 4.6 0.054 13.5 3.0 1.6 1 1 0 1 1 1 0 Protein trafficking PGA2 S-methyl_trans PF02574.16 KFX94320.1 - 8.2e-25 88.1 0.0 1e-24 87.8 0.0 1.1 1 0 0 1 1 1 1 Homocysteine S-methyltransferase Peripla_BP_4 PF13407.6 KFX94320.1 - 0.0041 16.7 0.0 0.0056 16.3 0.0 1.1 1 0 0 1 1 1 1 Periplasmic binding protein domain Thi4 PF01946.17 KFX94331.1 - 0.0086 15.3 0.0 0.011 15.0 0.0 1.2 1 0 0 1 1 1 1 Thi4 family bZIP_1 PF00170.21 KFX94331.1 - 0.021 14.9 13.9 0.11 12.5 13.9 1.9 1 1 0 1 1 1 0 bZIP transcription factor DivIC PF04977.15 KFX94331.1 - 0.15 11.8 0.2 0.26 11.1 0.2 1.3 1 0 0 1 1 1 0 Septum formation initiator bZIP_2 PF07716.15 KFX94331.1 - 6.2 7.0 13.2 1.4 9.1 0.4 2.2 2 0 0 2 2 2 0 Basic region leucine zipper EF-hand_1 PF00036.32 KFX94332.1 - 1.4e-17 61.9 2.0 5.9e-07 28.6 0.0 3.4 3 0 0 3 3 3 3 EF hand EF-hand_7 PF13499.6 KFX94332.1 - 5.1e-17 62.1 0.8 1.5e-10 41.3 0.2 2.3 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 KFX94332.1 - 2.4e-15 55.0 0.9 2.8e-06 26.8 0.0 3.6 3 0 0 3 3 3 2 EF-hand domain EF-hand_8 PF13833.6 KFX94332.1 - 2.6e-12 46.4 5.7 4.1e-08 33.0 0.4 3.2 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_5 PF13202.6 KFX94332.1 - 1.2e-08 34.1 2.3 2.7e-05 23.4 0.1 3.6 3 0 0 3 3 3 2 EF hand EF-hand_9 PF14658.6 KFX94332.1 - 0.015 15.6 0.0 0.15 12.4 0.0 2.2 2 0 0 2 2 2 0 EF-hand domain SPARC_Ca_bdg PF10591.9 KFX94332.1 - 0.043 14.1 0.1 0.12 12.7 0.1 1.7 2 0 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 KFX94332.1 - 0.089 12.8 0.0 0.89 9.5 0.0 2.3 2 1 1 3 3 3 0 Cytoskeletal-regulatory complex EF hand Hexapep PF00132.24 KFX94333.1 - 4e-15 54.9 13.5 2.1e-07 30.4 0.5 3.6 2 1 1 3 3 3 3 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 KFX94333.1 - 1.5e-13 50.2 15.9 8.6e-07 28.6 0.2 3.3 3 0 0 3 3 3 2 Hexapeptide repeat of succinyl-transferase Zn_clus PF00172.18 KFX94333.1 - 1.2e-09 38.1 14.7 3.4e-09 36.7 14.7 1.8 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Mac PF12464.8 KFX94333.1 - 5.6e-05 23.3 0.0 9.6e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 Maltose acetyltransferase Opy2 PF09463.10 KFX94333.1 - 6.8 7.1 10.8 3 8.2 3.7 3.1 3 0 0 3 3 3 0 Opy2 protein DUF3295 PF11702.8 KFX94334.1 - 6.1e-67 227.1 26.9 1.1e-31 110.7 6.3 3.0 1 1 2 3 3 3 3 Protein of unknown function (DUF3295) DUF1752 PF08550.10 KFX94334.1 - 0.0027 17.5 9.6 0.0062 16.3 9.6 1.6 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) GalP_UDP_transf PF01087.22 KFX94343.1 - 1.3e-71 240.8 0.1 6.1e-70 235.4 0.1 2.2 2 0 0 2 2 2 1 Galactose-1-phosphate uridyl transferase, N-terminal domain GalP_UDP_tr_C PF02744.17 KFX94343.1 - 3.3e-59 199.4 0.1 5.9e-59 198.5 0.1 1.4 1 0 0 1 1 1 1 Galactose-1-phosphate uridyl transferase, C-terminal domain HIT PF01230.23 KFX94343.1 - 0.0041 17.8 0.0 0.083 13.6 0.0 2.3 2 0 0 2 2 2 1 HIT domain Filament PF00038.21 KFX94343.1 - 0.12 11.9 0.0 0.2 11.2 0.0 1.2 1 0 0 1 1 1 0 Intermediate filament protein DUF4921 PF16268.5 KFX94343.1 - 0.23 10.3 0.4 0.86 8.3 0.0 2.1 2 1 0 2 2 2 0 Domain of unknown function (DUF4921) DIE2_ALG10 PF04922.12 KFX94344.1 - 1.4e-62 212.3 0.0 1.8e-62 211.9 0.0 1.1 1 0 0 1 1 1 1 DIE2/ALG10 family Isochorismatase PF00857.20 KFX94346.1 - 5.6e-22 78.8 0.0 8.6e-22 78.1 0.0 1.3 1 0 0 1 1 1 1 Isochorismatase family Voltage_CLC PF00654.20 KFX94348.1 - 1.3e-88 297.7 20.9 1.3e-88 297.7 20.9 1.7 2 0 0 2 2 2 1 Voltage gated chloride channel PTPLA PF04387.14 KFX94353.1 - 6.1e-46 156.2 7.4 6.1e-46 156.2 7.4 1.4 2 0 0 2 2 2 1 Protein tyrosine phosphatase-like protein, PTPLA HMGL-like PF00682.19 KFX94354.1 - 4.8e-66 223.0 0.0 1e-65 222.0 0.0 1.4 2 0 0 2 2 2 1 HMGL-like PS_Dcarbxylase PF02666.15 KFX94355.1 - 1.9e-48 164.7 0.0 2.4e-48 164.3 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase Glyco_hydro_2_C PF02836.17 KFX94355.1 - 0.14 11.2 0.0 0.22 10.6 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolases family 2, TIM barrel domain PSDC PF12588.8 KFX94355.1 - 0.17 11.9 0.1 0.4 10.6 0.0 1.6 2 0 0 2 2 2 0 Phophatidylserine decarboxylase p450 PF00067.22 KFX94356.1 - 4.1e-51 174.2 0.0 4.8e-51 173.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 MFS_1 PF07690.16 KFX94357.1 - 5e-39 134.2 30.6 2.7e-32 112.1 23.1 2.0 2 0 0 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 KFX94357.1 - 3.8e-09 35.4 1.1 3.8e-09 35.4 1.1 3.5 2 1 1 3 3 3 2 Organic Anion Transporter Polypeptide (OATP) family Zn_clus PF00172.18 KFX94359.1 - 4.3e-05 23.5 8.8 8.5e-05 22.6 8.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KFX94359.1 - 9.4e-05 21.6 0.0 0.00017 20.8 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain VCBS PF13517.6 KFX94360.1 - 1.1e-38 131.6 74.3 1.3e-09 38.5 5.4 8.3 3 3 5 8 8 8 8 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella Lipase_GDSL_2 PF13472.6 KFX94360.1 - 8e-14 52.4 0.2 1.9e-13 51.2 0.2 1.7 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family TcdB_toxin_midN PF12256.8 KFX94360.1 - 7.8e-10 38.4 21.2 1.3 8.4 0.2 9.0 4 1 4 9 9 9 5 Insecticide toxin TcdB middle/N-terminal region Lipase_GDSL PF00657.22 KFX94360.1 - 3.9e-08 33.5 0.2 3.9e-08 33.5 0.2 1.8 2 0 0 2 2 2 1 GDSL-like Lipase/Acylhydrolase FG-GAP PF01839.23 KFX94360.1 - 1e-07 31.9 52.6 0.46 10.7 0.3 10.0 9 0 0 9 9 9 6 FG-GAP repeat Dockerin_1 PF00404.18 KFX94360.1 - 2.9e-05 24.1 15.3 7.2 6.9 0.0 7.9 8 0 0 8 8 8 3 Dockerin type I domain Lipase_GDSL_3 PF14606.6 KFX94360.1 - 0.02 15.0 0.0 0.049 13.8 0.0 1.7 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase family Itfg2 PF15907.5 KFX94360.1 - 0.029 13.4 11.1 13 4.7 0.1 5.8 5 1 2 7 7 7 0 Integrin-alpha FG-GAP repeat-containing protein 2 DUF1186 PF06685.11 KFX94360.1 - 6.6 6.0 6.1 4.7 6.5 0.6 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1186) adh_short PF00106.25 KFX94362.1 - 7.9e-28 97.2 0.2 1e-27 96.9 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KFX94362.1 - 1.5e-21 77.0 0.0 1.7e-21 76.9 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KFX94362.1 - 3.8e-07 30.2 0.0 5.5e-07 29.7 0.0 1.3 1 1 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 KFX94362.1 - 0.00089 19.2 0.0 0.0039 17.1 0.0 1.9 1 1 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KFX94362.1 - 0.1 12.0 0.0 0.17 11.3 0.0 1.4 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family MFS_1 PF07690.16 KFX94364.1 - 2.9e-46 158.0 36.8 2.9e-46 158.0 36.8 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KFX94364.1 - 1.1e-12 47.6 29.3 1e-11 44.4 29.3 2.2 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_4 PF06779.14 KFX94364.1 - 3.2e-05 23.4 4.2 3.2e-05 23.4 4.2 3.1 3 0 0 3 3 3 1 Uncharacterised MFS-type transporter YbfB TRI12 PF06609.13 KFX94364.1 - 0.00025 19.6 5.1 0.00038 19.0 4.2 1.6 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) OATP PF03137.20 KFX94364.1 - 0.066 11.5 10.0 0.21 9.8 3.9 2.8 1 1 1 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family LPD38 PF18857.1 KFX94364.1 - 0.16 12.1 2.1 2.3 8.3 0.2 2.3 2 0 0 2 2 2 0 Large polyvalent protein associated domain 38 ATP-synt_B PF00430.18 KFX94364.1 - 0.55 10.3 1.9 1.2 9.2 1.9 1.6 1 0 0 1 1 1 0 ATP synthase B/B' CF(0) ABM PF03992.16 KFX94365.1 - 0.0015 18.6 0.4 0.36 11.0 0.2 2.3 2 0 0 2 2 2 2 Antibiotic biosynthesis monooxygenase Mito_carr PF00153.27 KFX94375.1 - 6.5e-43 144.6 9.8 9.2e-16 57.5 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Spore_YtrH PF14034.6 KFX94375.1 - 0.027 14.6 0.6 0.42 10.8 0.4 2.9 2 2 0 2 2 2 0 Sporulation protein YtrH Pyridoxal_deC PF00282.19 KFX94376.1 - 1.5e-73 247.7 0.0 2e-73 247.3 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.19 KFX94376.1 - 0.00069 18.7 0.0 0.00099 18.2 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V OKR_DC_1 PF01276.20 KFX94376.1 - 0.032 13.0 0.4 0.22 10.2 0.0 2.0 2 0 0 2 2 2 0 Orn/Lys/Arg decarboxylase, major domain Metallothio_PEC PF02068.16 KFX94380.1 - 0.19 12.1 25.0 0.11 12.9 5.5 3.2 3 0 0 3 3 3 0 Plant PEC family metallothionein Metallothio_2 PF01439.18 KFX94380.1 - 9.7 7.2 30.7 0.52 11.2 5.1 2.7 2 2 0 2 2 2 0 Metallothionein SH3_3 PF08239.11 KFX94381.1 - 0.16 12.3 0.0 0.35 11.2 0.0 1.5 1 0 0 1 1 1 0 Bacterial SH3 domain SH3_3 PF08239.11 KFX94382.1 - 0.012 15.9 0.0 0.018 15.3 0.0 1.3 1 0 0 1 1 1 0 Bacterial SH3 domain EGF_Tenascin PF18720.1 KFX94382.1 - 0.36 10.9 0.2 0.36 10.9 0.2 2.4 1 1 1 2 2 2 0 Tenascin EGF domain Fungal_trans PF04082.18 KFX94384.1 - 4.6e-24 84.9 1.3 5e-24 84.8 0.0 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KFX94384.1 - 8.6e-08 32.2 13.7 1.5e-07 31.4 13.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Miff PF05644.11 KFX94384.1 - 0.35 10.5 3.4 0.5 10.0 3.4 1.2 1 0 0 1 1 1 0 Mitochondrial and peroxisomal fission factor Mff PAT1 PF09770.9 KFX94384.1 - 1.3 7.3 9.3 1.6 6.9 9.3 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 MR_MLE_C PF13378.6 KFX94385.1 - 5.3e-41 140.6 0.0 8.4e-41 139.9 0.0 1.2 1 0 0 1 1 1 1 Enolase C-terminal domain-like MR_MLE_N PF02746.16 KFX94385.1 - 5.6e-09 36.2 0.0 9.4e-09 35.5 0.0 1.3 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain adh_short_C2 PF13561.6 KFX94386.1 - 6.2e-56 189.6 0.3 8.4e-56 189.1 0.3 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KFX94386.1 - 5.5e-44 150.0 1.0 8.2e-44 149.4 1.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KFX94386.1 - 7.5e-09 35.8 1.3 1.1e-08 35.2 1.3 1.1 1 0 0 1 1 1 1 KR domain PCI PF01399.27 KFX94387.1 - 1.4e-20 73.7 0.1 2.6e-20 72.9 0.1 1.4 1 0 0 1 1 1 1 PCI domain RPN6_C_helix PF18503.1 KFX94387.1 - 6.6e-10 38.6 0.1 1.2e-09 37.7 0.1 1.5 1 0 0 1 1 1 1 26S proteasome subunit RPN6 C-terminal helix domain DDRGK PF09756.9 KFX94387.1 - 0.0036 16.9 1.0 0.0056 16.3 1.0 1.4 1 1 0 1 1 1 1 DDRGK domain HTH_Crp_2 PF13545.6 KFX94387.1 - 0.081 12.9 0.0 0.2 11.7 0.0 1.8 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain NepR PF18557.1 KFX94387.1 - 0.1 12.3 0.0 0.21 11.3 0.0 1.5 1 0 0 1 1 1 0 Anti-sigma factor NepR Cadherin_C_2 PF16492.5 KFX94391.1 - 0.11 13.3 0.0 0.14 12.9 0.0 1.3 1 0 0 1 1 1 0 Cadherin cytoplasmic C-terminal Phosphodiest PF01663.22 KFX94392.1 - 5e-16 59.2 0.3 8.6e-16 58.5 0.3 1.3 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.23 KFX94392.1 - 1.8e-05 24.3 0.0 4.4e-05 23.0 0.0 1.5 1 1 0 1 1 1 1 Sulfatase Metalloenzyme PF01676.18 KFX94392.1 - 0.00014 21.3 1.4 0.00024 20.6 1.4 1.2 1 0 0 1 1 1 1 Metalloenzyme superfamily zf-C2H2 PF00096.26 KFX94398.1 - 9.4e-09 35.3 13.0 4.8e-05 23.6 1.7 3.1 2 0 0 2 2 2 2 Zinc finger, C2H2 type Zn_clus PF00172.18 KFX94398.1 - 2.7e-05 24.2 9.5 2.7e-05 24.2 9.5 2.2 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-C2H2_4 PF13894.6 KFX94398.1 - 0.0009 19.9 17.9 0.0029 18.3 1.4 3.4 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFX94398.1 - 0.0044 17.3 3.9 0.11 12.8 0.6 2.8 1 1 1 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-H2C2_2 PF13465.6 KFX94398.1 - 0.01 16.2 3.0 0.01 16.2 3.0 4.2 5 0 0 5 5 5 0 Zinc-finger double domain DZR PF12773.7 KFX94398.1 - 0.048 13.7 0.5 0.048 13.7 0.5 2.6 2 0 0 2 2 2 0 Double zinc ribbon DUF4187 PF13821.6 KFX94398.1 - 0.062 13.1 0.0 0.19 11.6 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4187) zf-C2H2_11 PF16622.5 KFX94398.1 - 0.069 12.9 6.5 3.8 7.4 1.6 2.8 2 0 0 2 2 2 0 zinc-finger C2H2-type zf-C2H2_6 PF13912.6 KFX94398.1 - 0.24 11.5 4.8 4.5 7.4 0.2 2.8 2 0 0 2 2 2 0 C2H2-type zinc finger zf-met PF12874.7 KFX94398.1 - 5.8 7.5 13.8 0.94 10.0 0.5 3.6 4 0 0 4 4 4 0 Zinc-finger of C2H2 type Abhydrolase_6 PF12697.7 KFX94403.1 - 1.5e-12 48.6 0.8 1.8e-12 48.3 0.8 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF2873 PF11395.8 KFX94407.1 - 0.15 11.9 2.2 0.72 9.8 2.2 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2873) PMP1_2 PF08114.11 KFX94407.1 - 4.5 7.1 10.6 0.22 11.3 1.3 3.1 2 1 1 3 3 3 0 ATPase proteolipid family Epimerase PF01370.21 KFX94408.1 - 6.2e-11 42.2 0.0 8.5e-11 41.8 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 KFX94408.1 - 6e-07 29.5 0.1 2.2e-06 27.7 0.1 1.8 2 0 0 2 2 2 1 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 KFX94408.1 - 2.8e-05 23.7 0.1 7.4e-05 22.3 0.1 1.8 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 KFX94408.1 - 3.6e-05 22.9 0.0 7.3e-05 21.9 0.0 1.5 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.25 KFX94408.1 - 0.00013 21.5 0.0 0.0057 16.1 0.0 2.3 2 0 0 2 2 2 1 short chain dehydrogenase NmrA PF05368.13 KFX94408.1 - 0.00014 21.6 0.1 0.00021 21.0 0.1 1.3 1 0 0 1 1 1 1 NmrA-like family UDPG_MGDP_dh_N PF03721.14 KFX94408.1 - 0.0058 16.2 0.1 0.022 14.3 0.1 1.8 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain RmlD_sub_bind PF04321.17 KFX94408.1 - 0.18 10.9 0.0 1.7 7.7 0.0 2.4 2 1 0 2 2 2 0 RmlD substrate binding domain Sacchrp_dh_NADP PF03435.18 KFX94409.1 - 6.5e-17 62.0 0.0 1.3e-16 61.1 0.0 1.5 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Lipase_GDSL_2 PF13472.6 KFX94410.1 - 3e-09 37.5 0.2 4.1e-09 37.1 0.2 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family IDO PF01231.18 KFX94411.1 - 5.8e-13 48.4 0.0 2.3e-10 39.8 0.0 2.3 2 0 0 2 2 2 2 Indoleamine 2,3-dioxygenase Cyt-b5 PF00173.28 KFX94411.1 - 1e-11 44.8 0.0 3.3e-11 43.1 0.0 1.9 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain FAD_binding_1 PF00667.20 KFX94411.1 - 1.4e-10 41.1 0.0 3e-10 40.1 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain NAD_binding_1 PF00175.21 KFX94411.1 - 9.4e-09 35.9 0.0 2e-08 34.9 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Zn_clus PF00172.18 KFX94412.1 - 9.9e-07 28.8 15.3 9.9e-07 28.8 15.3 1.8 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DBP PF12361.8 KFX94412.1 - 0.017 15.0 0.7 0.028 14.3 0.7 1.2 1 0 0 1 1 1 0 Duffy-antigen binding protein zf-C2H2 PF00096.26 KFX94412.1 - 2.8 8.6 7.8 0.16 12.5 0.9 2.5 2 0 0 2 2 2 0 Zinc finger, C2H2 type adh_short PF00106.25 KFX94413.1 - 5.8e-31 107.5 0.1 9.4e-31 106.8 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KFX94413.1 - 7.1e-21 74.8 0.0 1.1e-20 74.2 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase APH PF01636.23 KFX94413.1 - 3.2e-08 33.8 0.0 1.1e-07 32.1 0.0 1.8 1 1 0 1 1 1 1 Phosphotransferase enzyme family KR PF08659.10 KFX94413.1 - 5e-08 33.1 0.0 8.5e-08 32.3 0.0 1.3 1 0 0 1 1 1 1 KR domain Choline_kinase PF01633.20 KFX94413.1 - 6.4e-06 25.9 0.0 1.1e-05 25.1 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase Epimerase PF01370.21 KFX94413.1 - 0.00095 18.7 0.0 0.0017 17.8 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Pkinase PF00069.25 KFX94413.1 - 0.0081 15.6 0.0 3 7.1 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain 3Beta_HSD PF01073.19 KFX94413.1 - 0.064 12.3 0.1 0.13 11.2 0.1 1.6 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family F-box PF00646.33 KFX94415.1 - 0.0059 16.5 0.5 0.016 15.1 0.5 1.8 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 KFX94415.1 - 0.11 12.4 1.6 0.25 11.3 1.6 1.6 1 0 0 1 1 1 0 F-box-like ArfGap PF01412.18 KFX94417.1 - 3.6e-32 110.9 0.0 6.5e-32 110.1 0.0 1.4 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf RRM_1 PF00076.22 KFX94418.1 - 2.8e-30 103.9 0.0 2.1e-14 53.1 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KFX94418.1 - 0.00045 20.3 0.0 0.18 12.0 0.0 2.6 2 1 0 2 2 2 2 RNA recognition motif RRM_5 PF13893.6 KFX94418.1 - 0.0024 17.4 0.0 0.4 10.3 0.0 3.0 3 0 0 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF4783 PF16022.5 KFX94418.1 - 0.026 14.7 0.0 0.35 11.1 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4783) DUF4944 PF16302.5 KFX94418.1 - 0.03 14.4 0.1 1.4 9.0 0.0 2.7 3 1 0 3 3 3 0 Domain of unknown function (DUF4944) PHM7_cyt PF14703.6 KFX94418.1 - 0.043 14.1 0.0 11 6.2 0.0 3.0 2 1 0 3 3 3 0 Cytosolic domain of 10TM putative phosphate transporter FXMRP1_C_core PF12235.8 KFX94418.1 - 0.085 13.5 12.3 0.042 14.5 9.4 1.9 2 0 0 2 2 2 0 Fragile X-related 1 protein core C terminal FAD_binding_1 PF00667.20 KFX94419.1 - 3.6e-34 118.3 0.0 7.1e-34 117.3 0.0 1.5 2 0 0 2 2 2 1 FAD binding domain Flavodoxin_1 PF00258.25 KFX94419.1 - 7.9e-29 100.7 0.0 1.2e-28 100.1 0.0 1.3 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.21 KFX94419.1 - 1.4e-07 32.1 0.0 3.6e-07 30.8 0.0 1.7 1 1 0 1 1 1 1 Oxidoreductase NAD-binding domain Putative_PNPOx PF01243.20 KFX94422.1 - 1e-14 54.5 0.1 1.1e-13 51.1 0.0 2.5 3 0 0 3 3 3 1 Pyridoxamine 5'-phosphate oxidase Pyridox_ox_2 PF12900.7 KFX94422.1 - 0.0035 17.4 0.0 0.16 12.0 0.0 2.2 2 0 0 2 2 2 2 Pyridoxamine 5'-phosphate oxidase Nitroreductase PF00881.24 KFX94423.1 - 1.3e-16 61.1 0.0 1.6e-16 60.8 0.0 1.1 1 0 0 1 1 1 1 Nitroreductase family PsbY PF06298.11 KFX94423.1 - 0.013 15.3 0.1 0.031 14.2 0.1 1.5 1 0 0 1 1 1 0 Photosystem II protein Y (PsbY) ABC_tran PF00005.27 KFX94424.1 - 9.6e-17 61.8 0.1 3.4e-16 60.0 0.0 1.9 2 0 0 2 2 2 1 ABC transporter SMC_N PF02463.19 KFX94424.1 - 0.0038 16.7 0.0 0.0069 15.9 0.0 1.5 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain SbcCD_C PF13558.6 KFX94424.1 - 0.017 15.4 3.0 0.41 10.9 1.5 3.1 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit ABC_ATPase PF09818.9 KFX94424.1 - 0.03 13.1 0.1 0.03 13.1 0.1 1.4 2 0 0 2 2 2 0 Predicted ATPase of the ABC class PBP_sp32 PF07222.12 KFX94424.1 - 8.5 5.8 8.2 12 5.2 8.2 1.2 1 0 0 1 1 1 0 Proacrosin binding protein sp32 FAD_binding_1 PF00667.20 KFX94425.1 - 4.4e-57 193.2 0.0 2e-35 122.4 0.0 2.1 1 1 1 2 2 2 2 FAD binding domain NAD_binding_1 PF00175.21 KFX94425.1 - 5.4e-06 27.0 0.0 1.1e-05 26.0 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Perm-CXXC PF15629.6 KFX94425.1 - 0.1 12.9 1.1 19 5.6 0.1 2.4 2 0 0 2 2 2 0 Permuted single zf-CXXC unit CAF1 PF04857.20 KFX94431.1 - 1e-79 268.1 0.3 1.2e-79 267.8 0.3 1.1 1 0 0 1 1 1 1 CAF1 family ribonuclease DNA_pol_A_exo1 PF01612.20 KFX94431.1 - 0.0036 17.0 0.1 0.0092 15.7 0.1 1.7 2 0 0 2 2 2 1 3'-5' exonuclease Ub-RnfH PF03658.14 KFX94431.1 - 0.16 12.3 0.0 0.37 11.2 0.0 1.6 1 0 0 1 1 1 0 RnfH family Ubiquitin Pex26 PF07163.12 KFX94432.1 - 0.013 14.8 2.5 0.013 14.8 2.5 1.7 2 0 0 2 2 2 0 Pex26 protein DUF572 PF04502.13 KFX94432.1 - 2.5 7.7 8.1 0.99 9.0 5.1 1.7 2 0 0 2 2 2 0 Family of unknown function (DUF572) PHF5 PF03660.14 KFX94433.1 - 2.1e-35 121.1 6.2 3e-35 120.6 6.2 1.2 1 0 0 1 1 1 1 PHF5-like protein PhoLip_ATPase_C PF16212.5 KFX94434.1 - 1.3e-82 277.3 18.8 1.3e-82 277.3 18.8 2.2 2 0 0 2 2 2 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 KFX94434.1 - 5.8e-26 90.0 8.3 1.5e-25 88.6 8.3 1.8 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal Cation_ATPase PF13246.6 KFX94434.1 - 1.6e-10 40.9 0.0 6.3e-10 39.0 0.0 2.0 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 KFX94434.1 - 1.7e-10 41.6 2.7 1.2e-06 28.9 0.5 3.0 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 KFX94434.1 - 3.1e-06 26.8 0.0 6.4e-06 25.8 0.0 1.5 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase_3 PF08282.12 KFX94434.1 - 0.00081 19.2 0.1 0.0094 15.7 0.0 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase APH PF01636.23 KFX94435.1 - 1.5e-13 51.2 0.1 2.3e-13 50.6 0.1 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KFX94435.1 - 0.0095 15.5 0.0 0.013 15.1 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase DUF3224 PF11528.8 KFX94436.1 - 3.1e-16 59.3 1.8 6.9e-16 58.2 1.8 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF3224) DUF1902 PF08972.11 KFX94459.1 - 0.024 14.6 0.0 0.035 14.1 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1902) Abhydrolase_1 PF00561.20 KFX94461.1 - 1.1e-16 61.3 0.1 3.6e-16 59.6 0.0 1.9 1 1 1 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KFX94461.1 - 2.5e-16 61.0 0.0 3.1e-16 60.7 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KFX94461.1 - 9.2e-11 41.5 0.0 1.3e-10 41.0 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 DUF1057 PF06342.12 KFX94461.1 - 0.00069 18.7 0.0 0.0009 18.4 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1057) PGAP1 PF07819.13 KFX94461.1 - 0.0066 16.2 0.0 0.0093 15.7 0.0 1.2 1 0 0 1 1 1 1 PGAP1-like protein Ndr PF03096.14 KFX94461.1 - 0.036 12.8 0.0 0.15 10.7 0.0 1.9 3 0 0 3 3 3 0 Ndr family FAD_binding_4 PF01565.23 KFX94463.1 - 3.4e-21 75.5 2.5 7.1e-21 74.4 2.5 1.6 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 KFX94463.1 - 3.9e-11 42.9 0.1 9.8e-11 41.6 0.1 1.7 1 0 0 1 1 1 1 Berberine and berberine like DSPc PF00782.20 KFX94464.1 - 5.3e-21 74.8 0.0 1.2e-20 73.6 0.0 1.6 1 1 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 KFX94464.1 - 0.0041 16.7 0.0 0.006 16.2 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase BacA PF02673.18 KFX94464.1 - 0.02 14.6 0.0 0.028 14.1 0.0 1.3 1 0 0 1 1 1 0 Bacitracin resistance protein BacA AAA PF00004.29 KFX94466.1 - 4.8e-21 75.6 0.8 2.5e-20 73.2 0.0 2.6 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KFX94466.1 - 4.4e-05 23.9 0.2 0.00031 21.2 0.2 2.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 KFX94466.1 - 0.00059 20.1 0.3 0.014 15.7 0.0 2.8 1 1 1 2 2 2 1 AAA domain AAA_5 PF07728.14 KFX94466.1 - 0.00092 19.2 0.0 0.0023 18.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_24 PF13479.6 KFX94466.1 - 0.0073 16.0 0.0 0.02 14.7 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 KFX94466.1 - 0.0081 16.3 0.0 0.025 14.8 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_2 PF07724.14 KFX94466.1 - 0.016 15.3 0.0 0.072 13.2 0.0 2.1 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) AAA_19 PF13245.6 KFX94466.1 - 0.016 15.5 0.0 0.071 13.4 0.0 2.1 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 KFX94466.1 - 0.025 15.0 0.4 0.57 10.6 0.0 2.9 3 0 0 3 3 3 0 RNA helicase RuvB_N PF05496.12 KFX94466.1 - 0.028 14.2 0.0 0.051 13.3 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_14 PF13173.6 KFX94466.1 - 0.032 14.3 0.0 0.32 11.0 0.0 2.8 2 1 0 2 2 2 0 AAA domain AAA_25 PF13481.6 KFX94466.1 - 0.038 13.6 0.0 0.16 11.5 0.0 2.0 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.17 KFX94466.1 - 0.1 12.3 0.0 0.2 11.3 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein NAAA-beta PF15508.6 KFX94466.1 - 0.13 12.6 0.1 0.96 9.8 0.0 2.5 2 0 0 2 2 2 0 beta subunit of N-acylethanolamine-hydrolyzing acid amidase Sigma54_activ_2 PF14532.6 KFX94466.1 - 0.15 12.2 0.3 2.7 8.1 0.0 2.7 3 0 0 3 3 3 0 Sigma-54 interaction domain AAA_11 PF13086.6 KFX94466.1 - 1.9 8.2 0.0 1.9 8.2 0.0 3.4 3 0 0 3 3 3 0 AAA domain Acetyltransf_1 PF00583.25 KFX94467.1 - 4e-06 27.0 0.1 6e-06 26.5 0.1 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KFX94467.1 - 0.00054 19.9 0.0 0.00093 19.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KFX94467.1 - 0.0026 18.1 0.0 0.0077 16.6 0.0 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.6 KFX94467.1 - 0.087 12.5 0.0 1.2 8.8 0.0 2.1 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain ADH_zinc_N PF00107.26 KFX94468.1 - 3.6e-12 46.4 0.0 6.5e-12 45.6 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KFX94468.1 - 1.8e-05 25.8 0.0 3e-05 25.1 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KFX94468.1 - 0.00022 21.1 0.1 0.0017 18.2 0.0 2.2 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain Glyco_hyd_65N_2 PF14498.6 KFX94469.1 - 4.6e-48 164.1 0.1 9.4e-48 163.1 0.1 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 65, N-terminal domain Dynamin_N PF00350.23 KFX94469.1 - 1.7e-19 70.5 0.0 3.8e-19 69.4 0.0 1.6 1 1 0 1 1 1 1 Dynamin family Dynamin_M PF01031.20 KFX94469.1 - 9.6e-19 67.7 0.8 1.8e-18 66.8 0.8 1.5 1 0 0 1 1 1 1 Dynamin central region MMR_HSR1 PF01926.23 KFX94469.1 - 8.2e-05 22.7 0.0 0.00021 21.4 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase GED PF02212.18 KFX94469.1 - 0.0013 18.9 2.6 0.0057 16.8 0.0 2.9 3 0 0 3 3 3 1 Dynamin GTPase effector domain FeoB_N PF02421.18 KFX94469.1 - 0.044 13.3 0.0 12 5.4 0.0 2.4 2 0 0 2 2 2 0 Ferrous iron transport protein B DUF608 PF04685.13 KFX94469.1 - 0.058 12.6 0.0 0.11 11.6 0.0 1.4 1 0 0 1 1 1 0 Glycosyl-hydrolase family 116, catalytic region Roc PF08477.13 KFX94469.1 - 0.11 12.7 0.0 1 9.6 0.0 2.4 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase MFS_1 PF07690.16 KFX94470.1 - 1e-34 120.0 37.8 6.1e-29 101.0 24.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KFX94470.1 - 6.5e-13 48.3 6.4 6.5e-13 48.3 6.4 2.3 2 0 0 2 2 2 1 Sugar (and other) transporter PUCC PF03209.15 KFX94470.1 - 0.85 8.6 21.5 0.26 10.2 5.7 3.2 2 1 1 3 3 3 0 PUCC protein MatE PF01554.18 KFX94471.1 - 4.8e-54 182.4 25.2 4.9e-28 97.8 9.2 2.4 3 0 0 3 3 3 2 MatE Polysacc_synt_C PF14667.6 KFX94471.1 - 2.3e-08 34.2 6.0 2.3e-08 34.2 6.0 4.2 3 2 0 3 3 3 1 Polysaccharide biosynthesis C-terminal domain Arginase PF00491.21 KFX94472.1 - 8.2e-15 55.0 0.0 9.9e-15 54.8 0.0 1.1 1 0 0 1 1 1 1 Arginase family TGT PF01702.18 KFX94487.1 - 1e-132 442.6 0.0 7.7e-81 272.0 0.0 2.0 1 1 0 2 2 2 2 Queuine tRNA-ribosyltransferase HNH_2 PF13391.6 KFX94489.1 - 3.4e-08 33.5 0.0 6.9e-08 32.5 0.0 1.5 1 0 0 1 1 1 1 HNH endonuclease Beta-lactamase PF00144.24 KFX94490.1 - 3.9e-39 134.8 0.1 5.3e-39 134.4 0.1 1.1 1 0 0 1 1 1 1 Beta-lactamase Fungal_trans_2 PF11951.8 KFX94491.1 - 7.3e-10 38.2 0.4 1.3e-09 37.4 0.0 1.5 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KFX94491.1 - 2.8e-07 30.5 10.1 4.8e-07 29.8 10.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain p450 PF00067.22 KFX94492.1 - 7.9e-48 163.3 0.0 1.1e-47 162.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 PIG-X PF08320.12 KFX94492.1 - 0.046 13.6 0.1 0.097 12.6 0.0 1.5 2 0 0 2 2 2 0 PIG-X / PBN1 IBN_N PF03810.19 KFX94493.1 - 5.7e-09 35.8 0.0 2.5e-08 33.7 0.0 2.2 2 0 0 2 2 2 1 Importin-beta N-terminal domain Xpo1 PF08389.12 KFX94493.1 - 0.017 15.2 0.0 0.086 12.9 0.0 2.4 2 0 0 2 2 2 0 Exportin 1-like protein DUF742 PF05331.11 KFX94493.1 - 0.09 12.6 1.4 9.6 6.1 0.3 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF742) CAS_CSE1 PF03378.15 KFX94493.1 - 0.16 10.4 0.0 0.31 9.5 0.0 1.5 1 0 0 1 1 1 0 CAS/CSE protein, C-terminus HORMA PF02301.18 KFX94494.1 - 2.4e-11 43.6 0.0 4.4e-11 42.8 0.0 1.4 1 1 0 1 1 1 1 HORMA domain Chromo PF00385.24 KFX94497.1 - 1.5e-17 63.2 3.9 6.7e-08 32.3 0.2 2.3 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain Mtf2_C PF14061.6 KFX94497.1 - 0.37 11.0 3.1 3.4 7.9 0.1 2.3 2 0 0 2 2 2 0 Polycomb-like MTF2 factor 2 IGPD PF00475.18 KFX94506.1 - 2.4e-59 199.8 0.2 3.8e-59 199.1 0.2 1.3 1 0 0 1 1 1 1 Imidazoleglycerol-phosphate dehydratase Rep_fac_C PF08542.11 KFX94508.1 - 1.8e-23 82.7 0.1 7.2e-23 80.8 0.0 2.1 2 0 0 2 2 1 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.6 KFX94508.1 - 3.3e-12 46.5 0.0 2.9e-09 36.9 0.0 2.3 1 1 0 1 1 1 1 DNA polymerase III, delta subunit AAA PF00004.29 KFX94508.1 - 2.5e-11 44.1 0.0 4.6e-11 43.3 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.6 KFX94508.1 - 1.4e-06 28.4 0.0 2.7e-06 27.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KFX94508.1 - 9.6e-06 26.1 0.1 0.00094 19.6 0.0 2.4 1 1 1 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 KFX94508.1 - 3.2e-05 24.2 0.1 0.079 13.2 0.0 2.7 2 1 1 3 3 2 2 AAA domain Viral_helicase1 PF01443.18 KFX94508.1 - 9.6e-05 22.2 0.0 0.00017 21.4 0.0 1.4 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase RuvB_N PF05496.12 KFX94508.1 - 0.0004 20.2 0.0 0.00088 19.1 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_3 PF07726.11 KFX94508.1 - 0.00049 20.0 0.0 0.00093 19.1 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 KFX94508.1 - 0.0011 18.9 0.0 0.0025 17.8 0.0 1.5 1 1 0 1 1 1 1 Rad17 P-loop domain Mg_chelatase PF01078.21 KFX94508.1 - 0.0024 17.3 0.1 0.034 13.5 0.1 2.5 2 1 1 3 3 3 1 Magnesium chelatase, subunit ChlI TniB PF05621.11 KFX94508.1 - 0.0048 16.3 0.1 1.4 8.3 0.0 2.3 2 0 0 2 2 2 1 Bacterial TniB protein MeaB PF03308.16 KFX94508.1 - 0.0081 15.2 0.0 0.014 14.4 0.0 1.4 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_11 PF13086.6 KFX94508.1 - 0.0094 15.8 0.0 0.015 15.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KFX94508.1 - 0.011 16.1 0.2 0.049 14.0 0.2 2.1 1 1 0 1 1 1 0 AAA domain DNA_pol3_delta PF06144.13 KFX94508.1 - 0.014 15.2 0.0 0.025 14.4 0.0 1.4 1 0 0 1 1 1 0 DNA polymerase III, delta subunit DEAD PF00270.29 KFX94508.1 - 0.025 14.4 0.1 0.68 9.7 0.0 2.4 1 1 1 2 2 2 0 DEAD/DEAH box helicase NTPase_1 PF03266.15 KFX94508.1 - 0.026 14.4 0.1 0.12 12.2 0.1 2.1 1 1 1 2 2 2 0 NTPase AAA_30 PF13604.6 KFX94508.1 - 0.038 13.7 0.1 0.11 12.2 0.1 1.7 1 1 0 1 1 1 0 AAA domain AAA_assoc_2 PF16193.5 KFX94508.1 - 0.038 14.3 0.0 0.11 12.8 0.0 1.9 1 0 0 1 1 1 0 AAA C-terminal domain AAA_24 PF13479.6 KFX94508.1 - 0.042 13.6 0.0 0.11 12.2 0.0 1.7 2 0 0 2 2 2 0 AAA domain KTI12 PF08433.10 KFX94508.1 - 0.057 12.9 0.0 0.1 12.1 0.0 1.4 1 0 0 1 1 1 0 Chromatin associated protein KTI12 RNA_helicase PF00910.22 KFX94508.1 - 0.11 12.9 0.0 0.42 11.0 0.0 2.0 1 1 0 1 1 1 0 RNA helicase AAA_25 PF13481.6 KFX94508.1 - 0.17 11.5 0.0 0.6 9.6 0.1 1.9 1 1 0 1 1 1 0 AAA domain Asp PF00026.23 KFX94509.1 - 1.1e-71 241.9 1.9 1.4e-71 241.5 1.9 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KFX94509.1 - 1.4e-14 54.7 1.6 8.2e-12 45.7 0.9 3.2 2 1 0 2 2 2 2 Xylanase inhibitor N-terminal TAXi_C PF14541.6 KFX94509.1 - 0.0016 18.2 0.0 0.0037 17.1 0.0 1.6 1 0 0 1 1 1 1 Xylanase inhibitor C-terminal MerC PF03203.14 KFX94510.1 - 0.036 14.5 2.3 0.044 14.2 2.3 1.1 1 0 0 1 1 1 0 MerC mercury resistance protein SPDY PF03771.16 KFX94511.1 - 0.13 12.3 1.5 0.41 10.6 1.4 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF317) HTH_32 PF13565.6 KFX94513.1 - 8.1e-09 36.0 5.9 0.00055 20.5 1.2 2.4 1 1 1 2 2 2 2 Homeodomain-like domain HTH_23 PF13384.6 KFX94513.1 - 0.0081 15.9 0.3 0.015 15.1 0.3 1.4 1 0 0 1 1 1 1 Homeodomain-like domain HTH_38 PF13936.6 KFX94513.1 - 0.063 13.0 0.9 0.3 10.9 0.9 2.2 1 1 0 1 1 1 0 Helix-turn-helix domain HTH_29 PF13551.6 KFX94513.1 - 0.12 12.5 1.0 0.61 10.1 0.2 2.2 1 1 1 2 2 2 0 Winged helix-turn helix Helicase_C PF00271.31 KFX94514.1 - 2.3e-17 63.3 0.2 3.3e-17 62.8 0.2 1.3 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 KFX94515.1 - 2.1e-26 92.7 0.1 7.4e-25 87.7 0.1 2.3 1 1 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 KFX94515.1 - 9.8e-05 22.4 0.0 0.00035 20.6 0.0 2.0 1 1 1 2 2 2 1 Type III restriction enzyme, res subunit SNF2_N PF00176.23 KFX94515.1 - 0.019 13.7 0.9 0.044 12.5 0.0 1.7 2 0 0 2 2 2 0 SNF2 family N-terminal domain MPP6 PF10175.9 KFX94515.1 - 9 6.8 13.5 3.8 8.0 0.4 3.1 3 0 0 3 3 3 0 M-phase phosphoprotein 6 ATP-synt_G PF04718.15 KFX94516.1 - 7.3e-32 110.2 1.9 8.3e-32 110.0 0.1 2.1 2 1 0 2 2 2 1 Mitochondrial ATP synthase g subunit ADH_N PF08240.12 KFX94516.1 - 8.3e-28 96.4 2.3 1.6e-27 95.6 2.3 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KFX94516.1 - 2.1e-16 60.1 0.0 4.1e-16 59.1 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 KFX94516.1 - 1e-06 28.4 0.6 2.3e-05 24.0 0.6 2.4 1 1 0 1 1 1 1 Glucose dehydrogenase C-terminus 2-Hacid_dh_C PF02826.19 KFX94517.1 - 1.3e-46 158.2 0.0 7.1e-46 155.8 0.0 2.0 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 KFX94517.1 - 5.1e-07 29.4 0.0 1.4e-06 28.0 0.0 1.8 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain ELYS PF13934.6 KFX94520.1 - 2.5e-62 210.8 0.5 3e-62 210.5 0.5 1.1 1 0 0 1 1 1 1 Nuclear pore complex assembly SMC_N PF02463.19 KFX94521.1 - 2.4e-74 249.5 11.1 1.1e-73 247.4 11.1 2.1 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 KFX94521.1 - 9.3e-24 84.0 0.0 3e-23 82.3 0.0 2.0 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.6 KFX94521.1 - 3.5e-10 40.2 8.9 4.7e-05 23.3 0.4 3.5 2 2 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system Tektin PF03148.14 KFX94521.1 - 8.3e-05 21.5 13.0 8.3e-05 21.5 13.0 6.7 2 2 2 5 5 3 1 Tektin family AAA_29 PF13555.6 KFX94521.1 - 0.0006 19.5 0.0 0.0013 18.4 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain Taxilin PF09728.9 KFX94521.1 - 0.002 17.4 40.3 0.002 17.4 40.3 4.2 3 1 0 3 3 2 1 Myosin-like coiled-coil protein DivIC PF04977.15 KFX94521.1 - 0.017 14.9 0.6 0.017 14.9 0.6 10.7 8 5 5 13 13 13 0 Septum formation initiator GAS PF13851.6 KFX94521.1 - 0.48 9.7 125.3 0.0086 15.4 9.6 7.6 2 2 4 7 7 7 0 Growth-arrest specific micro-tubule binding ABC_tran PF00005.27 KFX94521.1 - 2 9.0 0.0 2 9.0 0.0 6.4 3 2 0 3 3 1 0 ABC transporter DUF3644 PF12358.8 KFX94521.1 - 3 8.4 9.3 0.19 12.3 0.8 3.4 3 0 0 3 3 2 0 Protein of unknown function (DUF3644) AAA_13 PF13166.6 KFX94521.1 - 4.5 5.8 99.2 0.017 13.8 30.3 5.8 2 2 4 6 6 6 0 AAA domain Plasmid_RAQPRD PF09686.10 KFX94521.1 - 8.2 6.7 12.2 0.11 12.7 0.4 4.2 3 2 1 4 4 4 0 Plasmid protein of unknown function (Plasmid_RAQPRD) Y_phosphatase PF00102.27 KFX94522.1 - 8.5e-46 156.4 0.0 1.2e-45 155.9 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.20 KFX94522.1 - 0.0032 17.3 0.0 0.0094 15.8 0.0 1.7 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.6 KFX94522.1 - 0.028 14.5 0.0 0.062 13.4 0.0 1.6 2 0 0 2 2 2 0 Inositol hexakisphosphate Y_phosphatase3 PF13350.6 KFX94522.1 - 0.057 13.4 0.0 0.09 12.7 0.0 1.3 1 0 0 1 1 1 0 Tyrosine phosphatase family Mrx7 PF10906.8 KFX94523.1 - 2.5e-11 43.6 0.0 6.7e-11 42.3 0.0 1.6 1 1 0 1 1 1 1 MIOREX complex component 7 DUF5102 PF17104.5 KFX94526.1 - 7.9e-81 272.3 5.1 1.9e-54 185.7 0.7 2.0 1 1 1 2 2 2 2 Domain of unknown function (DUF5102) LEM PF03020.15 KFX94526.1 - 0.045 13.3 0.1 14 5.3 0.0 2.6 2 0 0 2 2 2 0 LEM domain DUF1127 PF06568.11 KFX94526.1 - 0.11 12.3 1.8 10 5.9 0.1 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF1127) Aquarius_N PF16399.5 KFX94527.1 - 0.045 11.8 3.2 0.061 11.4 3.2 1.1 1 0 0 1 1 1 0 Intron-binding protein aquarius N-terminus Presenilin PF01080.17 KFX94527.1 - 8.7 5.0 5.8 12 4.5 5.8 1.3 1 0 0 1 1 1 0 Presenilin RRM_1 PF00076.22 KFX94528.1 - 9.9e-44 147.0 0.0 7.7e-17 60.9 0.0 3.1 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 KFX94528.1 - 1.4e-05 25.0 0.1 0.0016 18.4 0.0 3.0 3 0 0 3 3 3 1 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.11 KFX94528.1 - 6.2e-05 23.0 0.0 0.0012 18.8 0.0 2.5 3 0 0 3 3 3 1 RNA binding motif RRM_occluded PF16842.5 KFX94528.1 - 0.00017 21.4 0.0 0.059 13.2 0.0 2.6 3 0 0 3 3 3 2 Occluded RNA-recognition motif RRM_7 PF16367.5 KFX94528.1 - 0.0012 18.9 0.2 0.052 13.7 0.0 2.8 3 1 0 3 3 3 1 RNA recognition motif RRM_5 PF13893.6 KFX94528.1 - 0.018 14.7 0.0 0.063 12.9 0.0 1.9 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Endotoxin_N PF03945.14 KFX94531.1 - 0.028 14.1 0.1 0.052 13.3 0.1 1.4 1 0 0 1 1 1 0 delta endotoxin, N-terminal domain Integrase_H2C2 PF17921.1 KFX94531.1 - 0.044 13.9 0.0 0.09 12.9 0.0 1.5 1 0 0 1 1 1 0 Integrase zinc binding domain 4HBT PF03061.22 KFX94532.1 - 1.2e-11 44.8 0.0 2.3e-11 43.9 0.0 1.4 1 0 0 1 1 1 1 Thioesterase superfamily DUF3385 PF11865.8 KFX94536.1 - 0.0063 16.4 2.5 0.028 14.3 0.4 2.8 2 1 1 3 3 3 1 Domain of unknown function (DUF3385) UME PF08064.13 KFX94536.1 - 0.1 12.5 0.2 0.54 10.2 0.1 2.3 1 1 1 2 2 2 0 UME (NUC010) domain zf-rbx1 PF12678.7 KFX94538.1 - 1.5e-10 41.1 0.7 2.8e-10 40.3 0.7 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_2 PF13639.6 KFX94538.1 - 2.2e-08 34.3 5.0 5.8e-08 32.9 1.7 2.3 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.6 KFX94538.1 - 1.5e-06 28.0 5.0 7.3e-06 25.7 0.9 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KFX94538.1 - 2.8e-06 27.1 0.8 4.8e-06 26.3 0.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KFX94538.1 - 1.5e-05 24.9 1.3 3.3e-05 23.8 1.3 1.6 1 1 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 KFX94538.1 - 6.3e-05 22.7 0.3 0.00013 21.7 0.3 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 KFX94538.1 - 0.00019 21.4 1.4 0.0018 18.3 0.1 2.8 1 1 1 2 2 2 1 RING-type zinc-finger zf-RING_11 PF17123.5 KFX94538.1 - 0.00099 18.8 7.3 0.017 14.8 0.3 3.1 3 0 0 3 3 3 2 RING-like zinc finger zf-C3HC4_3 PF13920.6 KFX94538.1 - 0.0014 18.4 1.2 0.0014 18.4 1.2 1.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 KFX94538.1 - 0.0043 16.6 1.0 0.011 15.4 1.0 1.6 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type DUF2921 PF11145.8 KFX94538.1 - 0.012 13.4 0.3 0.018 12.9 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2921) zf-ANAPC11 PF12861.7 KFX94538.1 - 0.018 15.0 1.1 0.047 13.7 1.1 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger FANCL_C PF11793.8 KFX94538.1 - 0.57 10.4 2.9 2.3 8.4 2.9 2.1 1 1 0 1 1 1 0 FANCL C-terminal domain zf-RING_10 PF16685.5 KFX94538.1 - 1.1 9.5 2.4 33 4.7 0.8 2.3 2 0 0 2 2 2 0 zinc RING finger of MSL2 HSBP1 PF06825.12 KFX94539.1 - 2.4e-13 49.7 2.4 3.7e-13 49.1 2.4 1.2 1 0 0 1 1 1 1 Heat shock factor binding protein 1 CLZ PF16526.5 KFX94539.1 - 0.024 15.0 0.0 0.031 14.6 0.0 1.2 1 0 0 1 1 1 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels DUF2379 PF09543.10 KFX94539.1 - 0.07 13.3 0.1 0.082 13.1 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2379) CHDCT2 PF08074.11 KFX94539.1 - 0.096 12.9 0.1 0.11 12.7 0.1 1.1 1 0 0 1 1 1 0 CHDCT2 (NUC038) domain Thioredoxin PF00085.20 KFX94540.1 - 6e-56 186.8 0.0 2.4e-28 98.1 0.0 2.4 2 0 0 2 2 2 2 Thioredoxin ERp29 PF07749.12 KFX94540.1 - 9.1e-24 84.2 3.9 1.9e-23 83.2 3.9 1.6 1 0 0 1 1 1 1 Endoplasmic reticulum protein ERp29, C-terminal domain Thioredoxin_2 PF13098.6 KFX94540.1 - 7.5e-16 58.5 0.0 5.7e-09 36.4 0.0 3.3 3 1 0 3 3 3 2 Thioredoxin-like domain OST3_OST6 PF04756.13 KFX94540.1 - 9.5e-14 51.4 0.0 3.1e-06 26.7 0.0 2.1 1 1 1 2 2 2 2 OST3 / OST6 family, transporter family Thioredoxin_7 PF13899.6 KFX94540.1 - 2.4e-12 46.8 0.0 9.5e-05 22.5 0.0 2.5 2 0 0 2 2 2 2 Thioredoxin-like Thioredoxin_8 PF13905.6 KFX94540.1 - 3.9e-10 39.9 0.1 0.0045 17.3 0.0 3.6 3 1 0 3 3 3 2 Thioredoxin-like AhpC-TSA PF00578.21 KFX94540.1 - 2.6e-08 33.8 0.2 0.0054 16.6 0.0 2.5 1 1 1 2 2 2 2 AhpC/TSA family TraF PF13728.6 KFX94540.1 - 4.5e-07 29.9 0.0 0.00034 20.5 0.0 2.4 2 0 0 2 2 2 2 F plasmid transfer operon protein Redoxin PF08534.10 KFX94540.1 - 2.1e-06 27.5 0.7 0.06 13.1 0.0 3.0 3 0 0 3 3 3 2 Redoxin HyaE PF07449.11 KFX94540.1 - 2.8e-05 24.0 0.0 0.013 15.5 0.0 2.7 2 1 0 2 2 2 1 Hydrogenase-1 expression protein HyaE Thioredoxin_9 PF14595.6 KFX94540.1 - 0.0017 18.1 0.0 1.1 9.0 0.0 2.6 2 0 0 2 2 2 2 Thioredoxin Glutaredoxin PF00462.24 KFX94540.1 - 0.0039 17.4 0.1 5.1 7.4 0.0 3.3 2 1 0 2 2 2 1 Glutaredoxin Thioredoxin_3 PF13192.6 KFX94540.1 - 0.0046 17.0 0.0 2.6 8.2 0.0 3.3 4 0 0 4 4 4 1 Thioredoxin domain Helicase_C_4 PF13871.6 KFX94540.1 - 0.0067 16.1 0.0 0.012 15.3 0.0 1.4 1 0 0 1 1 1 1 C-terminal domain on Strawberry notch homologue DDE_Tnp_1_2 PF13586.6 KFX94540.1 - 0.058 13.8 0.0 0.93 9.9 0.0 2.7 3 0 0 3 3 3 0 Transposase DDE domain DUF953 PF06110.11 KFX94540.1 - 0.11 12.2 1.3 0.62 9.7 0.1 2.6 3 0 0 3 3 3 0 Eukaryotic protein of unknown function (DUF953) Gp-FAR-1 PF05823.12 KFX94540.1 - 0.71 10.2 8.3 1.3 9.3 8.3 1.4 1 0 0 1 1 1 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) DSBA PF01323.20 KFX94540.1 - 1.2 8.9 5.3 7.6 6.2 0.1 3.4 3 1 1 4 4 4 0 DSBA-like thioredoxin domain MKT1_C PF12246.8 KFX94541.1 - 9.5e-67 224.7 0.0 1.7e-66 223.9 0.0 1.4 1 0 0 1 1 1 1 Temperature dependent protein affecting M2 dsRNA replication MKT1_N PF12247.8 KFX94541.1 - 5e-31 106.9 0.2 1.6e-30 105.3 0.1 2.0 2 0 0 2 2 2 1 Temperature dependent protein affecting M2 dsRNA replication XPG_N PF00752.17 KFX94541.1 - 0.094 13.2 0.0 0.52 10.8 0.0 2.3 1 0 0 1 1 1 0 XPG N-terminal domain DUF1882 PF08966.11 KFX94542.1 - 0.041 14.1 0.1 0.11 12.8 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1882) Pfg27 PF09216.10 KFX94542.1 - 0.074 12.9 0.4 0.14 12.0 0.4 1.4 1 0 0 1 1 1 0 Pfg27 DNMT1-RFD PF12047.8 KFX94542.1 - 0.3 11.1 1.9 0.46 10.5 0.0 2.1 2 0 0 2 2 2 0 Cytosine specific DNA methyltransferase replication foci domain WRNPLPNID PF15017.6 KFX94542.1 - 5.2 8.0 11.4 3.2 8.7 7.9 2.4 2 0 0 2 2 2 0 Putative WW-binding domain and destruction box TruB_N PF01509.18 KFX94543.1 - 6e-48 163.0 0.2 1.8e-47 161.4 0.4 1.7 2 0 0 2 2 2 1 TruB family pseudouridylate synthase (N terminal domain) TruB_C_2 PF16198.5 KFX94543.1 - 1.3e-08 34.8 0.0 3.1e-08 33.6 0.0 1.7 1 0 0 1 1 1 1 tRNA pseudouridylate synthase B C-terminal domain Sec2p PF06428.11 KFX94544.1 - 1e-10 41.4 6.5 1e-10 41.4 6.5 2.1 2 0 0 2 2 2 1 GDP/GTP exchange factor Sec2p LMBR1 PF04791.16 KFX94544.1 - 0.011 14.7 0.9 0.013 14.5 0.9 1.0 1 0 0 1 1 1 0 LMBR1-like membrane protein V_ATPase_I PF01496.19 KFX94544.1 - 0.022 12.7 1.8 0.025 12.5 1.8 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family zinc_ribbon_9 PF14369.6 KFX94544.1 - 0.093 13.0 0.2 0.18 12.1 0.2 1.5 1 0 0 1 1 1 0 zinc-ribbon Jnk-SapK_ap_N PF09744.9 KFX94544.1 - 0.11 12.8 12.3 2.1 8.6 6.5 2.1 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 Mod_r PF07200.13 KFX94544.1 - 0.14 12.3 7.8 0.65 10.1 0.4 2.2 2 0 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein CsbD PF05532.12 KFX94544.1 - 0.19 11.6 0.8 0.54 10.2 0.8 1.7 1 0 0 1 1 1 0 CsbD-like DUF4795 PF16043.5 KFX94544.1 - 0.19 11.3 8.2 0.66 9.5 0.2 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4795) SlyX PF04102.12 KFX94544.1 - 0.51 11.0 18.9 3.9 8.1 5.9 3.6 2 2 0 2 2 2 0 SlyX DUF4407 PF14362.6 KFX94544.1 - 0.97 8.7 12.3 1.8 7.9 12.3 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) DUF3584 PF12128.8 KFX94544.1 - 4.6 4.6 14.5 17 2.8 14.5 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3584) COG2 PF06148.11 KFX94544.1 - 5.3 7.1 7.9 8.2 6.5 0.1 2.2 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 YlqD PF11068.8 KFX94544.1 - 5.4 7.4 11.7 3.7 7.9 4.0 2.1 2 0 0 2 2 2 0 YlqD protein Exonuc_VII_L PF02601.15 KFX94544.1 - 6.2 6.3 12.3 45 3.5 12.3 1.9 1 1 0 1 1 1 0 Exonuclease VII, large subunit GCN5L1 PF06320.13 KFX94544.1 - 6.8 6.9 10.0 0.79 9.9 3.2 2.1 2 0 0 2 2 2 0 GCN5-like protein 1 (GCN5L1) DnaJ_C PF01556.18 KFX94545.1 - 8.5e-39 133.0 0.4 2e-38 131.8 0.4 1.6 1 0 0 1 1 1 1 DnaJ C terminal domain Ribosomal_L32e PF01655.18 KFX94545.1 - 2.1e-30 105.3 0.1 4.5e-30 104.3 0.1 1.5 1 0 0 1 1 1 1 Ribosomal protein L32 DnaJ PF00226.31 KFX94545.1 - 1.1e-21 76.6 3.2 2.3e-21 75.7 3.2 1.5 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 KFX94545.1 - 7.2e-14 51.9 18.7 1.4e-13 51.0 18.7 1.5 1 0 0 1 1 1 1 DnaJ central domain Anti-TRAP PF15777.5 KFX94545.1 - 0.078 13.0 13.2 0.74 9.8 1.1 2.4 2 0 0 2 2 2 0 Tryptophan RNA-binding attenuator protein inhibitory protein HypA PF01155.19 KFX94545.1 - 0.091 12.8 7.5 2.8 8.0 0.6 2.5 2 0 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-RING_10 PF16685.5 KFX94545.1 - 0.22 11.7 6.3 1.3 9.2 0.3 2.4 2 0 0 2 2 2 0 zinc RING finger of MSL2 DUF1356 PF07092.12 KFX94545.1 - 6.6 5.9 7.4 9.3 5.4 0.2 2.6 1 1 2 3 3 3 0 Protein of unknown function (DUF1356) TackOD1 PF18551.1 KFX94545.1 - 9.9 5.8 9.5 53 3.4 1.4 2.1 1 1 1 2 2 2 0 Thaumarchaeal output domain 1 tRNA-synt_1c PF00749.21 KFX94546.1 - 2.5e-86 289.4 0.0 3.3e-86 289.0 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain JAB PF01398.21 KFX94547.1 - 2.5e-31 108.1 0.2 1.1e-30 106.0 0.0 2.0 2 0 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease CSN5_C PF18323.1 KFX94547.1 - 6.6e-21 75.0 1.0 1e-20 74.4 0.3 1.8 2 0 0 2 2 2 1 Cop9 signalosome subunit 5 C-terminal domain Prok-JAB PF14464.6 KFX94547.1 - 2.9e-05 23.8 0.0 4.7e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain UPF0172 PF03665.13 KFX94547.1 - 0.066 13.3 0.0 0.12 12.4 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0172) MAP65_ASE1 PF03999.12 KFX94548.1 - 1.1e-82 278.7 7.2 1.5e-82 278.3 7.2 1.2 1 0 0 1 1 1 1 Microtubule associated protein (MAP65/ASE1 family) DUF4073 PF13285.6 KFX94548.1 - 0.068 12.8 0.2 13 5.5 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4073) TipAS PF07739.13 KFX94548.1 - 0.33 11.5 2.5 1.6 9.3 0.2 3.1 2 1 0 3 3 3 0 TipAS antibiotic-recognition domain DUF1664 PF07889.12 KFX94548.1 - 1.9 8.6 4.0 24 5.0 0.5 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) BLOC1_2 PF10046.9 KFX94548.1 - 3 8.2 11.4 8.5 6.8 4.7 4.1 4 1 0 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 EF-hand_4 PF12763.7 KFX94549.1 - 0.00098 19.0 0.1 0.0022 17.9 0.1 1.5 1 0 0 1 1 1 1 Cytoskeletal-regulatory complex EF hand EF-hand_1 PF00036.32 KFX94549.1 - 0.015 14.8 0.0 0.029 13.9 0.0 1.4 1 0 0 1 1 1 0 EF hand Ferritin_2 PF13668.6 KFX94552.1 - 1.8e-10 41.2 3.2 4.3e-06 27.0 0.6 2.1 1 1 1 2 2 2 2 Ferritin-like domain WSC PF01822.19 KFX94555.1 - 4.1e-17 62.1 7.5 6.6e-17 61.5 7.5 1.3 1 0 0 1 1 1 1 WSC domain DUF3439 PF11921.8 KFX94555.1 - 1.1 9.2 10.4 0.74 9.8 8.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) Ank_2 PF12796.7 KFX94557.1 - 4.5e-41 139.3 0.5 3.6e-12 46.7 0.2 4.6 2 1 2 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KFX94557.1 - 2.8e-33 113.9 4.9 3.2e-08 33.9 0.1 6.2 3 1 3 6 6 6 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFX94557.1 - 2e-32 107.6 3.2 0.00024 21.3 0.0 8.0 7 0 0 7 7 7 6 Ankyrin repeat Ank PF00023.30 KFX94557.1 - 2.1e-27 94.3 6.5 0.0019 18.5 0.1 7.6 7 0 0 7 7 7 6 Ankyrin repeat Ank_5 PF13857.6 KFX94557.1 - 2e-23 82.1 7.9 2e-06 27.9 0.4 6.4 3 2 3 6 6 6 5 Ankyrin repeats (many copies) Helo_like_N PF17111.5 KFX94557.1 - 0.00057 19.3 1.6 0.0036 16.7 0.1 2.3 1 1 1 2 2 2 1 Fungal N-terminal domain of STAND proteins COesterase PF00135.28 KFX94558.1 - 2.2e-82 277.6 0.0 2.7e-82 277.3 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KFX94558.1 - 6.1e-05 23.0 0.0 0.00032 20.6 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KFX94558.1 - 0.013 14.9 0.1 0.021 14.3 0.1 1.2 1 0 0 1 1 1 0 Prolyl oligopeptidase family DUF4345 PF14248.6 KFX94560.1 - 1.6 8.6 7.5 1.3 9.0 1.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4345) Methyltransf_2 PF00891.18 KFX94561.1 - 1e-16 60.9 0.0 1.6e-16 60.3 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase domain Sel1 PF08238.12 KFX94562.1 - 1.3e-32 111.5 37.0 7.7e-05 23.2 0.6 12.1 12 1 1 13 13 13 9 Sel1 repeat TPR_7 PF13176.6 KFX94562.1 - 5.4e-05 22.9 3.6 14 5.9 0.0 6.6 6 0 0 6 6 6 1 Tetratricopeptide repeat Snapin_Pallidin PF14712.6 KFX94562.1 - 0.2 12.1 0.3 0.51 10.8 0.3 1.6 1 0 0 1 1 1 0 Snapin/Pallidin TPR_19 PF14559.6 KFX94562.1 - 0.26 11.8 6.2 0.39 11.3 1.3 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_17 PF13431.6 KFX94562.1 - 0.26 11.7 5.9 6.7 7.3 0.0 4.8 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.6 KFX94562.1 - 6.3 7.7 19.5 20 6.1 0.0 7.5 8 2 0 8 8 8 0 Tetratricopeptide repeat WD40 PF00400.32 KFX94563.1 - 7e-13 48.8 0.1 0.032 15.1 0.0 5.5 5 0 0 5 5 5 4 WD domain, G-beta repeat Cytochrom_D1 PF02239.16 KFX94563.1 - 8.6e-05 21.2 0.0 0.00014 20.5 0.0 1.3 1 0 0 1 1 1 1 Cytochrome D1 heme domain ANAPC4_WD40 PF12894.7 KFX94563.1 - 0.00012 22.3 0.0 1.1 9.7 0.0 3.3 3 0 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain NIF PF03031.18 KFX94564.1 - 8.1e-54 181.6 0.1 1.2e-53 181.0 0.1 1.3 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase Sec61_beta PF03911.16 KFX94565.1 - 4.8e-18 64.9 2.6 4.8e-18 64.9 2.6 1.7 2 0 0 2 2 2 1 Sec61beta family Axin_b-cat_bind PF08833.10 KFX94565.1 - 0.066 13.3 0.9 0.17 12.0 0.9 1.7 1 0 0 1 1 1 0 Axin beta-catenin binding domain DUF1180 PF06679.12 KFX94565.1 - 0.093 13.1 0.9 0.12 12.8 0.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) Clr2_transil PF16761.5 KFX94566.1 - 4.1e-12 46.7 0.3 9.7e-12 45.5 0.3 1.6 1 0 0 1 1 1 1 Transcription-silencing protein, cryptic loci regulator Clr2 Clr2 PF10383.9 KFX94566.1 - 3.2e-09 37.7 0.0 1.4e-08 35.6 0.0 2.0 1 1 0 1 1 1 1 Transcription-silencing protein Clr2 Fungal_trans_2 PF11951.8 KFX94568.1 - 0.0067 15.3 0.0 0.0097 14.7 0.0 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain FBD PF08387.10 KFX94568.1 - 0.038 13.9 0.0 0.076 12.9 0.0 1.5 1 0 0 1 1 1 0 FBD Aconitase PF00330.20 KFX94570.1 - 1.7e-146 488.9 0.0 1.9e-146 488.7 0.0 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Fn_bind PF02986.14 KFX94571.1 - 0.022 14.5 0.4 0.17 11.6 0.3 2.6 2 0 0 2 2 2 0 Fibronectin binding repeat Epimerase PF01370.21 KFX94576.1 - 2e-10 40.5 0.0 2.8e-10 40.1 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KFX94576.1 - 4.2e-10 39.1 0.0 5.9e-10 38.6 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 KFX94576.1 - 4.1e-08 33.3 0.1 6.5e-08 32.7 0.1 1.4 1 0 0 1 1 1 1 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 KFX94576.1 - 0.081 12.3 0.1 10 5.4 0.0 2.6 3 0 0 3 3 3 0 GDP-mannose 4,6 dehydratase Dynamin_M PF01031.20 KFX94577.1 - 2.8e-110 368.0 0.0 5.5e-110 367.1 0.0 1.5 1 0 0 1 1 1 1 Dynamin central region Dynamin_N PF00350.23 KFX94577.1 - 6.8e-57 192.2 0.5 2e-56 190.6 0.0 2.1 2 0 0 2 2 2 1 Dynamin family GED PF02212.18 KFX94577.1 - 1.2e-30 105.5 2.1 1.2e-30 105.5 2.1 2.5 2 0 0 2 2 2 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.23 KFX94577.1 - 6.9e-05 22.9 0.3 0.0014 18.7 0.3 2.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase SH3_9 PF14604.6 KFX94578.1 - 1.9e-28 98.0 3.3 9.3e-14 51.0 0.2 2.5 2 0 0 2 2 2 2 Variant SH3 domain SH3_1 PF00018.28 KFX94578.1 - 2.9e-26 90.8 5.1 1.2e-13 50.4 0.4 2.4 2 0 0 2 2 2 2 SH3 domain Cofilin_ADF PF00241.20 KFX94578.1 - 2.1e-16 59.8 0.0 4e-16 58.9 0.0 1.4 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein SH3_2 PF07653.17 KFX94578.1 - 1.6e-15 56.5 0.0 7.1e-07 28.8 0.0 2.7 2 0 0 2 2 2 2 Variant SH3 domain Dsl1_C PF11989.8 KFX94579.1 - 0.00032 20.5 0.0 0.0007 19.4 0.0 1.5 1 0 0 1 1 1 1 Retrograde transport protein Dsl1 C terminal Zw10 PF06248.13 KFX94579.1 - 0.019 13.5 0.4 0.031 12.9 0.4 1.2 1 0 0 1 1 1 0 Centromere/kinetochore Zw10 DUF3701 PF12482.8 KFX94579.1 - 0.055 13.5 0.1 0.23 11.6 0.1 2.1 1 0 0 1 1 1 0 Phage integrase protein CDC45 PF02724.14 KFX94579.1 - 0.94 7.7 5.1 2 6.6 5.1 1.4 1 0 0 1 1 1 0 CDC45-like protein LRR_4 PF12799.7 KFX94580.1 - 8.8e-07 29.2 7.3 0.18 12.2 0.1 6.0 4 2 1 5 5 5 2 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 KFX94580.1 - 0.061 12.8 0.1 4.9 6.6 0.1 2.6 1 1 0 2 2 2 0 Leucine-rich repeat LRR_6 PF13516.6 KFX94580.1 - 0.13 12.4 9.3 20 5.6 0.0 6.2 8 0 0 8 8 8 0 Leucine Rich repeat LRR_8 PF13855.6 KFX94580.1 - 0.91 9.3 8.9 0.18 11.6 0.3 3.9 5 1 0 5 5 5 0 Leucine rich repeat SNF2_N PF00176.23 KFX94581.1 - 5e-47 160.3 0.0 1.1e-45 155.9 0.0 2.4 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KFX94581.1 - 3.1e-16 59.7 0.0 8.1e-16 58.4 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-C3HC4 PF00097.25 KFX94581.1 - 1.2e-05 25.1 10.9 1.2e-05 25.1 10.9 2.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) ResIII PF04851.15 KFX94581.1 - 1.7e-05 24.9 0.0 3.5e-05 23.9 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit zf-RING_2 PF13639.6 KFX94581.1 - 0.0069 16.7 14.4 0.0069 16.7 14.4 3.1 3 0 0 3 3 3 1 Ring finger domain AAA_34 PF13872.6 KFX94581.1 - 0.0085 15.0 0.0 0.036 13.0 0.0 2.0 2 0 0 2 2 2 1 P-loop containing NTP hydrolase pore-1 ERCC3_RAD25_C PF16203.5 KFX94581.1 - 0.054 12.7 0.0 0.094 11.9 0.0 1.4 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase Pkinase PF00069.25 KFX94584.1 - 2.8e-08 33.5 0.0 4.6e-08 32.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 KFX94584.1 - 0.00011 22.3 0.1 0.00024 21.1 0.1 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_Tyr PF07714.17 KFX94584.1 - 0.0022 17.3 0.0 0.0038 16.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KFX94584.1 - 0.039 12.7 0.0 0.063 12.1 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Kdo PF06293.14 KFX94584.1 - 0.19 11.1 0.0 0.32 10.3 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family HD PF01966.22 KFX94587.1 - 5.8e-08 33.0 0.3 7.3e-08 32.7 0.3 1.2 1 0 0 1 1 1 1 HD domain Methyltransf_23 PF13489.6 KFX94588.1 - 1.1e-12 48.1 0.1 3e-12 46.7 0.0 1.8 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 KFX94588.1 - 7.9e-09 36.1 0.0 2.5e-08 34.5 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KFX94588.1 - 8.6e-05 23.1 0.0 0.00017 22.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KFX94588.1 - 8.8e-05 23.2 0.0 0.0008 20.1 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KFX94588.1 - 9.5e-05 22.2 0.0 0.0015 18.3 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.18 KFX94588.1 - 0.0029 17.0 0.0 0.0072 15.6 0.0 1.6 1 1 0 1 1 1 1 O-methyltransferase domain Methyltransf_PK PF05891.12 KFX94588.1 - 0.0086 15.6 0.2 0.017 14.7 0.2 1.4 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase CheR PF01739.18 KFX94588.1 - 0.034 13.6 0.0 0.056 12.9 0.0 1.2 1 0 0 1 1 1 0 CheR methyltransferase, SAM binding domain MTS PF05175.14 KFX94588.1 - 0.043 13.4 0.0 0.066 12.8 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_4 PF02390.17 KFX94588.1 - 0.045 13.2 0.0 0.074 12.5 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase Glyco_hydro_64 PF16483.5 KFX94589.1 - 1.5e-121 406.2 0.0 1.7e-121 406.0 0.0 1.0 1 0 0 1 1 1 1 Beta-1,3-glucanase DUF3383 PF11863.8 KFX94589.1 - 0.09 11.8 0.0 0.13 11.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3383) SLC35F PF06027.12 KFX94590.1 - 1.1e-101 340.3 25.0 1.3e-101 340.1 25.0 1.0 1 0 0 1 1 1 1 Solute carrier family 35 CRT-like PF08627.10 KFX94590.1 - 2.4e-10 39.9 5.3 4.5e-10 39.0 5.3 1.4 1 0 0 1 1 1 1 CRT-like, chloroquine-resistance transporter-like EamA PF00892.20 KFX94590.1 - 3.1e-06 27.4 39.1 0.0042 17.2 15.6 2.1 2 0 0 2 2 2 2 EamA-like transporter family TFIIA PF03153.13 KFX94590.1 - 0.25 11.3 0.1 0.34 10.8 0.1 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Tim17 PF02466.19 KFX94590.1 - 0.61 10.5 3.5 0.78 10.1 1.2 2.3 2 1 0 2 2 2 0 Tim17/Tim22/Tim23/Pmp24 family Condensation PF00668.20 KFX94593.1 - 1.1e-23 83.7 0.0 1.4e-23 83.3 0.0 1.1 1 0 0 1 1 1 1 Condensation domain PP-binding PF00550.25 KFX94593.1 - 4.6e-12 46.1 0.1 1.1e-11 44.9 0.1 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site RTC4 PF14474.6 KFX94595.1 - 1.8e-29 102.3 0.0 3e-29 101.6 0.0 1.3 1 0 0 1 1 1 1 RTC4-like domain Glyco_hydro_43 PF04616.14 KFX94595.1 - 8.4e-12 45.0 2.0 1.5e-11 44.1 2.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 zf-Mss51 PF13824.6 KFX94595.1 - 0.1 12.7 0.1 0.22 11.6 0.1 1.5 1 0 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 Cu-oxidase_3 PF07732.15 KFX94597.1 - 2.7e-42 143.6 0.6 2.7e-42 143.6 0.6 2.6 3 0 0 3 3 3 1 Multicopper oxidase Cu-oxidase PF00394.22 KFX94597.1 - 1.4e-29 103.2 6.3 1.6e-29 103.1 0.0 3.6 5 1 1 6 6 6 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 KFX94597.1 - 6.4e-29 100.4 10.8 4.2e-28 97.8 1.8 4.0 3 2 0 3 3 3 2 Multicopper oxidase p450 PF00067.22 KFX94598.1 - 4.1e-50 170.9 0.0 9.7e-50 169.6 0.0 1.5 1 1 0 1 1 1 1 Cytochrome P450 ketoacyl-synt PF00109.26 KFX94599.1 - 8.1e-75 251.7 0.0 2e-74 250.4 0.0 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain SAT PF16073.5 KFX94599.1 - 2.1e-73 247.0 1.2 5.2e-73 245.7 0.2 2.3 2 0 0 2 2 2 1 Starter unit:ACP transacylase in aflatoxin biosynthesis Acyl_transf_1 PF00698.21 KFX94599.1 - 5.6e-41 141.1 0.0 1e-40 140.2 0.0 1.5 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 KFX94599.1 - 1.7e-36 124.8 2.2 2.7e-36 124.1 0.9 2.2 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain Thioesterase PF00975.20 KFX94599.1 - 2.7e-23 83.3 0.0 5.7e-22 79.0 0.0 2.9 3 1 0 3 3 3 1 Thioesterase domain PP-binding PF00550.25 KFX94599.1 - 4.2e-23 81.5 2.5 2e-11 44.0 0.1 2.8 2 0 0 2 2 2 2 Phosphopantetheine attachment site PS-DH PF14765.6 KFX94599.1 - 1.1e-14 54.4 0.0 1.8e-14 53.7 0.0 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase Abhydrolase_6 PF12697.7 KFX94599.1 - 6.9e-06 26.8 2.1 0.00072 20.2 0.1 3.0 3 0 0 3 3 3 1 Alpha/beta hydrolase family Thiolase_N PF00108.23 KFX94599.1 - 0.0001 21.8 0.0 0.00032 20.2 0.0 1.8 1 0 0 1 1 1 1 Thiolase, N-terminal domain KAsynt_C_assoc PF16197.5 KFX94599.1 - 0.00069 20.0 0.1 0.0022 18.4 0.1 1.8 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension Abhydrolase_1 PF00561.20 KFX94599.1 - 0.037 13.7 0.0 0.096 12.3 0.0 1.6 1 0 0 1 1 1 0 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KFX94599.1 - 0.13 11.5 0.1 0.82 8.9 0.0 2.1 2 0 0 2 2 2 0 Serine aminopeptidase, S33 adh_short_C2 PF13561.6 KFX94600.1 - 6.8e-53 179.6 0.0 1.1e-52 178.9 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KFX94600.1 - 1e-45 155.6 0.0 1.5e-45 155.1 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KFX94600.1 - 5.5e-10 39.4 0.0 1.1e-09 38.4 0.0 1.5 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KFX94600.1 - 0.21 11.0 0.0 0.3 10.5 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family FAD_binding_4 PF01565.23 KFX94602.1 - 8.8e-26 90.3 1.7 1.3e-25 89.7 1.7 1.3 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 KFX94602.1 - 3.1e-13 49.6 0.0 6.1e-13 48.7 0.0 1.5 1 0 0 1 1 1 1 Berberine and berberine like Cupin_1 PF00190.22 KFX94607.1 - 9e-20 70.8 0.5 1.3e-19 70.2 0.5 1.2 1 0 0 1 1 1 1 Cupin Cupin_2 PF07883.11 KFX94607.1 - 0.00048 19.8 0.1 0.00083 19.0 0.1 1.4 1 0 0 1 1 1 1 Cupin domain MARVEL PF01284.23 KFX94608.1 - 0.0014 18.6 14.4 0.043 13.8 8.5 2.1 1 1 1 2 2 2 2 Membrane-associating domain Thymidylat_synt PF00303.19 KFX94610.1 - 3.5e-93 311.6 0.0 4.4e-93 311.3 0.0 1.0 1 0 0 1 1 1 1 Thymidylate synthase CDP-OH_P_transf PF01066.21 KFX94617.1 - 1.2e-11 45.3 0.5 1.2e-11 45.3 0.5 2.1 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase Thermopsin PF05317.11 KFX94617.1 - 0.052 13.0 0.1 0.076 12.5 0.1 1.1 1 0 0 1 1 1 0 Thermopsin SRP19 PF01922.17 KFX94618.1 - 2.5e-28 98.9 0.0 3.8e-28 98.3 0.0 1.2 1 0 0 1 1 1 1 SRP19 protein CBFB_NFYA PF02045.15 KFX94620.1 - 1.3e-27 96.2 4.6 1.3e-27 96.2 4.6 2.5 3 0 0 3 3 3 1 CCAAT-binding transcription factor (CBF-B/NF-YA) subunit B ORC6 PF05460.13 KFX94620.1 - 0.2 10.9 3.6 0.43 9.8 3.6 1.5 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) BRO1 PF03097.18 KFX94626.1 - 6.1e-132 440.1 2.3 6.1e-132 440.1 2.3 2.0 2 0 0 2 2 2 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.6 KFX94626.1 - 3.1e-77 259.8 13.4 3.1e-77 259.8 13.4 2.7 2 0 0 2 2 2 1 ALIX V-shaped domain binding to HIV Lon_C PF05362.13 KFX94626.1 - 8.6e-62 208.3 0.0 2e-61 207.2 0.0 1.6 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain LON_substr_bdg PF02190.16 KFX94626.1 - 3.8e-33 115.1 3.0 3.8e-33 115.1 0.1 2.5 2 0 0 2 2 2 1 ATP-dependent protease La (LON) substrate-binding domain AAA PF00004.29 KFX94626.1 - 4.9e-22 78.8 0.0 1.5e-21 77.2 0.0 1.9 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 KFX94626.1 - 1.3e-06 28.5 0.0 3.5e-06 27.0 0.0 1.8 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 KFX94626.1 - 4.8e-06 26.8 0.0 1.4e-05 25.3 0.0 1.8 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) ChlI PF13541.6 KFX94626.1 - 3.6e-05 23.6 0.0 9.7e-05 22.2 0.0 1.8 1 0 0 1 1 1 1 Subunit ChlI of Mg-chelatase AAA_22 PF13401.6 KFX94626.1 - 8e-05 22.9 0.2 0.0011 19.2 0.0 2.9 2 1 0 2 2 2 1 AAA domain AAA_PrkA PF08298.11 KFX94626.1 - 8.7e-05 21.6 0.0 0.00017 20.6 0.0 1.4 1 0 0 1 1 1 1 PrkA AAA domain RuvB_N PF05496.12 KFX94626.1 - 0.00016 21.4 0.0 0.0014 18.4 0.0 2.5 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 KFX94626.1 - 0.00047 20.6 1.1 0.0033 17.8 0.1 3.0 2 1 0 2 2 2 1 AAA ATPase domain RsgA_GTPase PF03193.16 KFX94626.1 - 0.0063 16.4 0.6 0.3 11.0 0.0 2.7 2 0 0 2 2 2 1 RsgA GTPase AAA_14 PF13173.6 KFX94626.1 - 0.022 14.8 0.0 0.07 13.2 0.0 1.9 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 KFX94626.1 - 0.033 13.9 0.0 0.13 12.0 0.0 1.9 2 0 0 2 2 2 0 IstB-like ATP binding protein RNA_helicase PF00910.22 KFX94626.1 - 0.11 12.9 0.0 0.4 11.1 0.0 2.0 1 0 0 1 1 1 0 RNA helicase AAA_18 PF13238.6 KFX94626.1 - 0.16 12.5 0.0 0.16 12.5 0.0 3.1 4 0 0 4 4 3 0 AAA domain GRP PF07172.11 KFX94626.1 - 0.54 11.0 8.2 1.8 9.3 8.2 1.9 1 0 0 1 1 1 0 Glycine rich protein family Pkinase PF00069.25 KFX94627.1 - 1.3e-11 44.4 0.0 2e-10 40.5 0.0 2.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFX94627.1 - 7.5e-10 38.5 0.0 9.2e-09 34.9 0.0 2.2 1 1 0 1 1 1 1 Protein tyrosine kinase HMG_box PF00505.19 KFX94639.1 - 3.6e-13 49.7 0.1 7e-13 48.8 0.1 1.5 1 0 0 1 1 1 1 HMG (high mobility group) box SAM_1 PF00536.30 KFX94639.1 - 1.2e-09 38.5 0.0 2.1e-09 37.7 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) HMG_box_2 PF09011.10 KFX94639.1 - 4.8e-09 36.7 0.1 1e-08 35.6 0.1 1.5 1 0 0 1 1 1 1 HMG-box domain SAM_2 PF07647.17 KFX94639.1 - 1e-07 32.0 0.0 2.5e-07 30.7 0.0 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 KFX94640.1 - 7.1e-11 42.4 0.1 8.5e-11 42.1 0.1 1.0 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 KFX94640.1 - 2.4e-05 24.3 0.0 2.7e-05 24.2 0.0 1.1 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) MapZ_EC1 PF18041.1 KFX94641.1 - 0.048 13.9 2.7 0.2 11.9 0.6 2.0 1 1 1 2 2 2 0 MapZ extracellular domain 1 APH PF01636.23 KFX94642.1 - 3.5e-11 43.5 0.0 1.3e-10 41.6 0.0 1.9 2 1 0 2 2 2 1 Phosphotransferase enzyme family Fructosamin_kin PF03881.14 KFX94642.1 - 0.19 10.9 0.0 2.9 7.0 0.0 2.2 2 0 0 2 2 2 0 Fructosamine kinase PI3K_P85_iSH2 PF16454.5 KFX94643.1 - 0.5 10.0 29.9 6.2 6.4 22.8 3.9 3 1 0 3 3 3 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain DUF5329 PF17263.2 KFX94643.1 - 1.8 8.8 6.8 0.55 10.5 0.2 3.0 3 0 0 3 3 3 0 Family of unknown function (DUF5329) DUF3435 PF11917.8 KFX94644.1 - 1.1e-109 367.1 0.0 1.7e-109 366.6 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3435) Phage_integrase PF00589.22 KFX94644.1 - 0.067 13.0 0.1 0.6 9.9 0.0 2.1 2 0 0 2 2 2 0 Phage integrase family HIT PF01230.23 KFX94645.1 - 2.6e-19 69.7 0.1 5.2e-19 68.8 0.0 1.5 2 0 0 2 2 2 1 HIT domain DcpS_C PF11969.8 KFX94645.1 - 4.1e-05 24.0 0.0 7.2e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding CwfJ_C_1 PF04677.15 KFX94645.1 - 0.0026 17.6 0.0 0.0074 16.2 0.0 1.8 2 0 0 2 2 2 1 Protein similar to CwfJ C-terminus 1 APH PF01636.23 KFX94646.1 - 8.2e-10 39.0 0.0 1.1e-09 38.6 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.20 KFX94646.1 - 4.5e-07 29.5 0.1 6.8e-07 28.9 0.1 1.2 1 0 0 1 1 1 1 Ecdysteroid kinase Choline_kinase PF01633.20 KFX94646.1 - 1.8e-06 27.7 0.2 5e-06 26.3 0.2 1.8 1 1 0 1 1 1 1 Choline/ethanolamine kinase Fructosamin_kin PF03881.14 KFX94646.1 - 0.00032 20.0 0.1 0.00049 19.4 0.1 1.4 1 0 0 1 1 1 1 Fructosamine kinase DUF1679 PF07914.11 KFX94646.1 - 0.0013 17.7 0.1 0.0018 17.2 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1679) TraQ PF09679.10 KFX94647.1 - 0.02 14.8 0.0 0.056 13.4 0.0 1.7 1 0 0 1 1 1 0 Type-F conjugative transfer system pilin chaperone (TraQ) Tti2 PF10521.9 KFX94647.1 - 2 7.9 5.2 0.55 9.7 0.1 2.1 2 0 0 2 2 2 0 Tti2 family Dynamin_N PF00350.23 KFX94648.1 - 3.5e-20 72.7 0.0 5.1e-19 68.9 0.0 2.6 1 1 0 1 1 1 1 Dynamin family Dynamin_M PF01031.20 KFX94648.1 - 1.2e-17 64.1 2.4 1.1e-12 47.7 0.2 2.4 2 0 0 2 2 2 2 Dynamin central region GED PF02212.18 KFX94648.1 - 1.8e-06 28.0 0.4 8.3e-06 25.9 0.4 2.1 1 0 0 1 1 1 1 Dynamin GTPase effector domain AAA_16 PF13191.6 KFX94648.1 - 0.00019 21.8 2.1 0.59 10.5 0.0 3.2 3 0 0 3 3 3 2 AAA ATPase domain MMR_HSR1 PF01926.23 KFX94648.1 - 0.00064 19.8 0.0 0.93 9.6 0.0 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase F-box PF00646.33 KFX94648.1 - 0.0087 15.9 0.0 0.023 14.6 0.0 1.7 1 0 0 1 1 1 1 F-box domain F-box_4 PF15966.5 KFX94648.1 - 0.029 14.2 0.0 0.077 12.9 0.0 1.7 1 0 0 1 1 1 0 F-box AbiTii PF18864.1 KFX94648.1 - 0.045 13.9 0.1 0.12 12.5 0.0 1.7 2 0 0 2 2 2 0 AbiTii ApbA_C PF08546.11 KFX94656.1 - 5.8e-33 113.8 0.0 8.3e-33 113.3 0.0 1.2 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.16 KFX94656.1 - 4.4e-19 68.6 0.0 1.2e-18 67.3 0.0 1.6 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA DsrH PF04077.12 KFX94656.1 - 0.098 12.8 0.0 0.23 11.6 0.0 1.6 1 0 0 1 1 1 0 DsrH like protein Pkinase PF00069.25 KFX94657.1 - 1.3e-53 182.1 0.0 2.2e-53 181.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFX94657.1 - 8e-32 110.5 0.0 1.3e-31 109.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KFX94657.1 - 5.7e-14 52.1 0.0 7.8e-11 41.8 0.0 2.3 2 0 0 2 2 2 2 Kinase-like Rep_fac_C PF08542.11 KFX94660.1 - 6e-20 71.5 0.1 1.2e-19 70.5 0.1 1.5 1 0 0 1 1 1 1 Replication factor C C-terminal domain AAA PF00004.29 KFX94660.1 - 1.6e-13 51.2 0.0 9.1e-13 48.8 0.0 2.2 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.6 KFX94660.1 - 4.1e-11 42.9 0.0 4.4e-08 33.1 0.0 2.4 2 0 0 2 2 2 2 DNA polymerase III, delta subunit Rad17 PF03215.15 KFX94660.1 - 1.2e-07 31.8 0.0 5.2e-07 29.8 0.0 2.0 3 0 0 3 3 3 1 Rad17 P-loop domain AAA_assoc_2 PF16193.5 KFX94660.1 - 3.3e-05 24.1 0.1 0.0001 22.5 0.1 1.9 1 0 0 1 1 1 1 AAA C-terminal domain AAA_11 PF13086.6 KFX94660.1 - 0.00031 20.6 0.0 0.00065 19.6 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KFX94660.1 - 0.00044 20.7 0.0 0.0084 16.5 0.0 2.4 1 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 KFX94660.1 - 0.0008 19.7 0.1 0.017 15.4 0.0 2.5 2 1 0 2 2 2 1 AAA domain RuvB_N PF05496.12 KFX94660.1 - 0.00081 19.2 0.0 0.0027 17.5 0.0 1.9 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain HSM3_N PF18795.1 KFX94660.1 - 0.0016 18.0 0.4 0.0023 17.4 0.4 1.2 1 0 0 1 1 1 1 DNA mismatch repair protein HSM3, N terminal domain AAA_24 PF13479.6 KFX94660.1 - 0.0031 17.3 0.0 0.0088 15.8 0.0 1.7 1 1 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 KFX94660.1 - 0.0056 16.1 0.0 0.43 9.9 0.0 2.5 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI DNA_pol3_delta PF06144.13 KFX94660.1 - 0.0066 16.2 0.0 0.016 15.0 0.0 1.6 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA_19 PF13245.6 KFX94660.1 - 0.013 15.9 0.0 0.27 11.6 0.0 2.5 2 1 0 2 2 2 0 AAA domain AAA_7 PF12775.7 KFX94660.1 - 0.035 13.6 0.0 0.066 12.7 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_30 PF13604.6 KFX94660.1 - 0.045 13.5 0.0 0.24 11.1 0.0 2.2 1 1 0 1 1 1 0 AAA domain DUF815 PF05673.13 KFX94660.1 - 0.055 12.6 0.0 0.089 11.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_5 PF07728.14 KFX94660.1 - 0.057 13.4 0.1 0.83 9.6 0.1 2.5 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_18 PF13238.6 KFX94660.1 - 0.14 12.8 0.0 0.41 11.2 0.0 1.9 1 1 0 1 1 1 0 AAA domain DUF2417 PF10329.9 KFX94661.1 - 6e-88 294.2 0.6 8.5e-88 293.8 0.6 1.1 1 0 0 1 1 1 1 Region of unknown function (DUF2417) TMEM51 PF15345.6 KFX94661.1 - 0.1 12.5 0.0 0.16 11.8 0.0 1.3 1 0 0 1 1 1 0 Transmembrane protein 51 Abhydrolase_6 PF12697.7 KFX94662.1 - 2.8e-23 83.7 0.4 4.1e-23 83.1 0.1 1.4 2 0 0 2 2 2 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KFX94662.1 - 3.3e-08 33.1 0.0 5e-08 32.5 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KFX94662.1 - 1.1e-06 28.5 0.0 2.4e-06 27.4 0.0 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold UPF0261 PF06792.11 KFX94662.1 - 0.0099 14.9 0.0 0.016 14.2 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0261) PGAP1 PF07819.13 KFX94662.1 - 0.049 13.3 0.0 0.083 12.6 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein Thioesterase PF00975.20 KFX94662.1 - 0.081 13.0 0.0 0.33 11.0 0.0 1.9 1 1 0 1 1 1 0 Thioesterase domain Esterase PF00756.20 KFX94662.1 - 0.15 11.7 0.0 0.24 11.0 0.0 1.3 1 0 0 1 1 1 0 Putative esterase Sec20 PF03908.13 KFX94663.1 - 9.7e-14 51.1 2.4 1.4e-13 50.6 0.0 2.4 3 1 0 3 3 3 1 Sec20 MRP_L53 PF10780.9 KFX94664.1 - 1.8e-21 76.0 1.1 3.6e-21 75.1 1.1 1.5 1 0 0 1 1 1 1 39S ribosomal protein L53/MRP-L53 RTC_insert PF05189.13 KFX94665.1 - 6.7e-31 106.9 0.0 1.4e-30 105.9 0.0 1.5 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase (RTC), insert domain RTC PF01137.21 KFX94665.1 - 1.1e-26 93.4 0.4 1.3e-26 93.1 0.4 1.1 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase RicinB_lectin_2 PF14200.6 KFX94666.1 - 1.8e-36 124.7 7.8 3.4e-16 59.8 0.2 3.5 2 1 2 4 4 4 3 Ricin-type beta-trefoil lectin domain-like F5_F8_type_C PF00754.25 KFX94666.1 - 5.7e-10 39.4 0.3 5.7e-10 39.4 0.3 2.2 2 0 0 2 2 2 1 F5/8 type C domain Ricin_B_lectin PF00652.22 KFX94666.1 - 9.7e-06 25.9 0.0 2.1e-05 24.8 0.0 1.6 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain Trehalase PF01204.18 KFX94666.1 - 0.0057 15.5 0.0 0.0096 14.8 0.0 1.3 1 0 0 1 1 1 1 Trehalase Glyco_hydro_61 PF03443.14 KFX94667.1 - 6.6e-65 218.9 0.2 7.6e-65 218.7 0.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 UDPGT PF00201.18 KFX94668.1 - 0.0002 20.3 0.0 0.00028 19.8 0.0 1.2 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase PWWP PF00855.17 KFX94669.1 - 1.1e-14 54.6 0.0 1.1e-14 54.6 0.0 4.1 3 2 1 4 4 4 1 PWWP domain Sec63 PF02889.16 KFX94670.1 - 3.4e-103 344.3 0.1 1.5e-70 237.3 0.0 2.2 2 0 0 2 2 2 2 Sec63 Brl domain DEAD PF00270.29 KFX94670.1 - 1.8e-17 63.7 0.1 4.9e-17 62.3 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase ResIII PF04851.15 KFX94670.1 - 3.4e-08 33.7 0.0 7.4e-08 32.6 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Pkinase PF00069.25 KFX94680.1 - 0.001 18.5 0.0 0.0013 18.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Zn_clus PF00172.18 KFX94682.1 - 4.4e-07 29.9 15.8 6.2e-07 29.4 15.8 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RST PF12174.8 KFX94682.1 - 0.02 14.8 0.0 0.03 14.2 0.0 1.3 1 0 0 1 1 1 0 RCD1-SRO-TAF4 (RST) plant domain Fungal_trans PF04082.18 KFX94683.1 - 8e-16 57.9 2.9 1.2e-15 57.3 1.6 1.9 2 0 0 2 2 2 1 Fungal specific transcription factor domain MITF_TFEB_C_3_N PF15951.5 KFX94683.1 - 0.13 12.9 5.7 0.27 11.9 5.7 1.5 1 0 0 1 1 1 0 MITF/TFEB/TFEC/TFE3 N-terminus Sugarporin_N PF11471.8 KFX94683.1 - 0.47 10.5 0.1 0.47 10.5 0.1 2.1 2 0 0 2 2 2 0 Maltoporin periplasmic N-terminal extension Mpv17_PMP22 PF04117.12 KFX94684.1 - 4e-21 75.0 2.2 4.9e-21 74.7 0.3 2.1 2 0 0 2 2 2 1 Mpv17 / PMP22 family PGK PF00162.19 KFX94685.1 - 2.9e-149 497.2 2.0 3.2e-149 497.0 2.0 1.0 1 0 0 1 1 1 1 Phosphoglycerate kinase DSS1_SEM1 PF05160.13 KFX94686.1 - 3.2e-23 81.5 17.1 4e-23 81.2 17.1 1.1 1 0 0 1 1 1 1 DSS1/SEM1 family Cwf_Cwc_15 PF04889.12 KFX94686.1 - 0.027 14.2 4.9 0.03 14.1 4.9 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein FAD_binding_4 PF01565.23 KFX94692.1 - 1.4e-22 79.9 1.1 2.5e-22 79.1 1.1 1.4 1 0 0 1 1 1 1 FAD binding domain SKG6 PF08693.10 KFX94693.1 - 9.8e-08 31.3 1.6 1.7e-07 30.5 1.6 1.3 1 0 0 1 1 1 1 Transmembrane alpha-helix domain DUF4448 PF14610.6 KFX94693.1 - 0.0001 22.1 0.0 0.00014 21.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) WSC PF01822.19 KFX94693.1 - 0.00016 21.8 2.7 0.00016 21.8 2.7 1.7 2 0 0 2 2 2 1 WSC domain Podoplanin PF05808.11 KFX94693.1 - 0.0018 18.4 0.1 0.0024 18.0 0.1 1.2 1 0 0 1 1 1 1 Podoplanin Alpha_GJ PF03229.13 KFX94693.1 - 0.0036 17.9 3.3 0.0052 17.3 3.3 1.2 1 0 0 1 1 1 1 Alphavirus glycoprotein J Phage_holin_2_4 PF16082.5 KFX94693.1 - 0.092 12.5 0.3 0.092 12.5 0.3 2.2 2 0 0 2 2 2 0 Bacteriophage holin family, superfamily II-like DUF5305 PF17231.2 KFX94693.1 - 0.17 11.3 0.0 0.24 10.8 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5305) KR PF08659.10 KFX94705.1 - 9.8e-60 201.5 0.0 2e-59 200.5 0.0 1.6 1 0 0 1 1 1 1 KR domain ADH_zinc_N PF00107.26 KFX94705.1 - 3.6e-14 52.9 1.7 7.7e-14 51.8 0.8 2.0 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KFX94705.1 - 5.3e-14 53.4 0.1 4.1e-13 50.5 0.1 2.5 1 1 0 1 1 1 1 Zinc-binding dehydrogenase adh_short PF00106.25 KFX94705.1 - 1.7e-10 40.7 1.2 2.8e-09 36.7 0.0 2.4 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 KFX94705.1 - 8.3e-07 28.8 0.2 0.00012 21.7 0.0 2.5 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase ADH_N PF08240.12 KFX94705.1 - 8.5e-07 28.8 1.6 1.7e-06 27.8 0.5 2.1 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain PP-binding PF00550.25 KFX94705.1 - 0.0049 17.2 0.0 0.011 16.1 0.0 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site Cnn_1N PF07989.11 KFX94736.1 - 1.1e-25 89.6 3.3 1.1e-25 89.6 3.3 14.6 6 3 5 12 12 12 2 Centrosomin N-terminal motif 1 PACT_coil_coil PF10495.9 KFX94736.1 - 1e-23 83.7 0.1 1e-23 83.7 0.1 5.1 5 1 0 5 5 5 1 Pericentrin-AKAP-450 domain of centrosomal targeting protein Spc7 PF08317.11 KFX94736.1 - 1.7e-05 23.8 191.0 0.017 14.0 20.9 8.6 2 2 7 9 9 9 7 Spc7 kinetochore protein CENP-F_leu_zip PF10473.9 KFX94736.1 - 9.3e-05 22.5 14.8 9.3e-05 22.5 14.8 11.5 3 3 7 10 10 10 4 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Fez1 PF06818.15 KFX94736.1 - 0.00027 21.4 172.3 0.0017 18.8 24.2 8.5 1 1 8 10 10 10 4 Fez1 Spc110_C PF18520.1 KFX94736.1 - 0.12 12.0 0.7 0.82 9.3 0.1 2.7 2 0 0 2 2 2 0 Spindle pole body component 110 C-terminal domain SGT1 PF07093.11 KFX94737.1 - 1.9e-95 320.5 20.3 5.2e-85 286.0 0.0 2.0 1 1 1 2 2 2 2 SGT1 protein APH PF01636.23 KFX94738.1 - 0.12 12.2 0.0 0.19 11.6 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family THUMP PF02926.17 KFX94739.1 - 3.2e-08 33.8 0.1 8.9e-07 29.1 0.0 2.5 2 1 0 2 2 2 1 THUMP domain TPP_enzyme_N PF02776.18 KFX94740.1 - 4.3e-31 107.8 0.0 7.3e-31 107.1 0.0 1.3 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.22 KFX94740.1 - 1.6e-20 73.3 0.0 2.9e-20 72.4 0.0 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.21 KFX94740.1 - 1e-13 51.3 0.0 3e-13 49.8 0.0 1.7 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain E1_dh PF00676.20 KFX94740.1 - 0.035 13.1 0.0 0.057 12.4 0.0 1.2 1 0 0 1 1 1 0 Dehydrogenase E1 component Pkinase PF00069.25 KFX94741.1 - 6.5e-61 206.0 0.0 2.2e-60 204.2 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFX94741.1 - 2.2e-45 155.0 0.0 4.2e-45 154.1 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KFX94741.1 - 2e-09 37.2 0.0 5.5e-06 25.9 0.0 2.7 3 0 0 3 3 3 2 Kinase-like Pkinase_fungal PF17667.1 KFX94741.1 - 0.0011 17.9 0.4 0.0025 16.7 0.0 1.7 2 0 0 2 2 2 1 Fungal protein kinase Kdo PF06293.14 KFX94741.1 - 0.022 14.1 0.0 0.038 13.3 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KFX94741.1 - 0.097 12.6 0.0 0.25 11.2 0.0 1.6 1 0 0 1 1 1 0 Phosphotransferase enzyme family Sugar_tr PF00083.24 KFX94743.1 - 9.9e-78 262.0 22.2 1.1e-77 261.8 22.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KFX94743.1 - 1.5e-32 112.9 34.9 3.3e-27 95.4 23.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 KFX94743.1 - 9e-07 27.7 7.1 1.4e-05 23.7 5.2 2.3 2 0 0 2 2 2 2 Fungal trichothecene efflux pump (TRI12) DUF3419 PF11899.8 KFX94751.1 - 1.3e-58 199.1 0.1 1.8e-58 198.6 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3419) DUF4448 PF14610.6 KFX94751.1 - 6.7e-38 130.4 0.0 1.2e-37 129.5 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) Methyltransf_23 PF13489.6 KFX94751.1 - 5.3e-12 45.9 0.0 1.7e-11 44.2 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 KFX94751.1 - 2.3e-09 37.9 0.0 1.2e-08 35.6 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 KFX94751.1 - 2.2e-07 31.5 0.0 4e-06 27.5 0.0 2.7 2 1 0 3 3 3 1 Methyltransferase domain Methyltransf_11 PF08241.12 KFX94751.1 - 4e-06 27.4 0.0 0.00022 21.8 0.0 2.9 3 0 0 3 3 3 1 Methyltransferase domain Ubie_methyltran PF01209.18 KFX94751.1 - 2.1e-05 24.0 0.0 0.017 14.4 0.0 2.3 2 0 0 2 2 2 2 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.6 KFX94751.1 - 2.4e-05 24.2 0.0 6.7e-05 22.7 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 KFX94751.1 - 0.0012 18.6 0.0 0.0022 17.8 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_32 PF13679.6 KFX94751.1 - 0.042 13.8 0.0 0.081 12.9 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Velvet PF11754.8 KFX94787.1 - 1.5e-43 149.6 0.8 2.6e-32 112.8 0.1 3.4 2 2 1 3 3 3 2 Velvet factor tRNA-synt_2c PF01411.19 KFX94789.1 - 1.7e-07 30.1 0.0 1.8e-07 30.0 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (A) Peptidase_M43 PF05572.13 KFX94790.1 - 5.6e-16 58.8 0.5 9.4e-16 58.1 0.5 1.4 1 0 0 1 1 1 1 Pregnancy-associated plasma protein-A Reprolysin_5 PF13688.6 KFX94790.1 - 5.1e-06 26.8 3.1 8.3e-06 26.1 3.1 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_3 PF13582.6 KFX94790.1 - 4.3e-05 24.0 0.1 8e-05 23.2 0.1 1.5 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M10 PF00413.24 KFX94790.1 - 0.001 19.0 0.0 0.0016 18.3 0.0 1.4 1 0 0 1 1 1 1 Matrixin Peptidase_M66 PF10462.9 KFX94790.1 - 0.0048 15.9 2.1 0.0064 15.5 1.6 1.4 1 1 0 1 1 1 1 Peptidase M66 Reprolysin_4 PF13583.6 KFX94790.1 - 0.011 15.4 1.5 0.011 15.4 0.1 1.7 2 0 0 2 2 2 0 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.6 KFX94790.1 - 0.015 15.2 1.3 0.028 14.3 0.9 1.4 1 1 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like DUF4953 PF16313.5 KFX94790.1 - 0.068 12.4 0.1 0.11 11.6 0.1 1.3 1 0 0 1 1 1 0 Met-zincin FmdA_AmdA PF03069.15 KFX94790.1 - 0.087 11.7 0.1 0.13 11.1 0.1 1.1 1 0 0 1 1 1 0 Acetamidase/Formamidase family Peptidase_M57 PF12388.8 KFX94790.1 - 0.1 12.2 3.4 0.19 11.3 3.3 1.6 1 1 0 1 1 1 0 Dual-action HEIGH metallo-peptidase Peptidase_M54 PF07998.11 KFX94790.1 - 0.19 11.7 0.0 0.32 11.0 0.0 1.3 1 0 0 1 1 1 0 Peptidase family M54 CYSTM PF12734.7 KFX94791.1 - 0.36 11.2 81.5 1.5e+02 2.8 62.7 5.3 1 1 1 2 2 2 0 Cysteine-rich TM module stress tolerance Pex14_N PF04695.13 KFX94791.1 - 3.3 8.4 6.7 4.2 8.0 6.7 1.2 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Shugoshin_N PF07558.11 KFX94792.1 - 0.13 12.2 1.7 0.18 11.7 0.1 2.0 2 0 0 2 2 2 0 Shugoshin N-terminal coiled-coil region FAS_I_H PF18314.1 KFX94796.1 - 4.8e-78 261.4 0.0 1.1e-77 260.3 0.0 1.7 1 0 0 1 1 1 1 Fatty acid synthase type I helical domain Fas_alpha_ACP PF18325.1 KFX94796.1 - 1.8e-74 249.5 0.0 3.5e-74 248.5 0.0 1.5 1 0 0 1 1 1 1 Fatty acid synthase subunit alpha Acyl carrier domain ketoacyl-synt PF00109.26 KFX94796.1 - 5e-19 68.9 0.0 9.8e-19 67.9 0.0 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 KFX94796.1 - 5.9e-11 42.4 0.3 1.9e-10 40.8 0.0 2.0 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain Bromodomain PF00439.25 KFX94810.1 - 6e-16 58.3 0.2 1.4e-15 57.1 0.2 1.7 1 0 0 1 1 1 1 Bromodomain Bromo_TP PF07524.13 KFX94810.1 - 1.5e-08 34.5 0.0 3.6e-08 33.3 0.0 1.6 1 0 0 1 1 1 1 Bromodomain associated DUF2398 PF09661.10 KFX94810.1 - 0.061 12.6 0.6 0.14 11.4 0.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2398) PAC1 PF16094.5 KFX94810.1 - 0.11 11.6 0.2 0.29 10.3 0.2 1.7 1 0 0 1 1 1 0 Proteasome assembly chaperone 4 Glucosamine_iso PF01182.20 KFX94813.1 - 8e-70 235.2 0.0 9e-70 235.0 0.0 1.0 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase SET PF00856.28 KFX94814.1 - 1.6e-05 25.3 0.0 5.8e-05 23.5 0.0 2.0 1 1 0 1 1 1 1 SET domain zf-MYND PF01753.18 KFX94814.1 - 0.0011 19.0 7.4 0.0011 19.0 7.4 2.3 2 0 0 2 2 2 1 MYND finger MA3 PF02847.17 KFX94816.1 - 1e-28 99.6 0.0 3.4e-28 97.9 0.0 1.9 2 0 0 2 2 2 1 MA3 domain MIF4G PF02854.19 KFX94816.1 - 1.7e-10 40.9 0.3 4.1e-10 39.7 0.3 1.7 1 0 0 1 1 1 1 MIF4G domain Na_trans_assoc PF06512.13 KFX94816.1 - 0.23 11.7 7.6 0.53 10.5 7.6 1.6 1 0 0 1 1 1 0 Sodium ion transport-associated DUF5523 PF17661.1 KFX94816.1 - 3.8 7.1 13.1 0.61 9.7 9.3 1.5 2 0 0 2 2 2 0 Family of unknown function (DUF5523) DPM2 PF07297.12 KFX94817.1 - 1.8e-30 105.0 1.4 3.2e-30 104.2 1.4 1.4 1 0 0 1 1 1 1 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) PIG-P PF08510.12 KFX94817.1 - 0.0057 16.6 0.9 0.013 15.4 0.9 1.6 1 0 0 1 1 1 1 PIG-P DUF4229 PF14012.6 KFX94817.1 - 0.11 12.6 0.9 0.33 11.1 0.9 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF4229) DUF1295 PF06966.12 KFX94819.1 - 1e-35 123.4 6.5 1.3e-35 123.0 6.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) Ribosomal_S18 PF01084.20 KFX94826.1 - 2.8e-14 53.0 0.0 6.2e-14 51.9 0.0 1.6 1 0 0 1 1 1 1 Ribosomal protein S18 RNA_pol_Rpb1_5 PF04998.17 KFX94826.1 - 0.095 12.1 0.0 0.12 11.8 0.0 1.4 1 1 0 1 1 1 0 RNA polymerase Rpb1, domain 5 PPR_2 PF13041.6 KFX94827.1 - 6.4e-11 42.3 0.5 0.5 10.6 0.0 6.6 7 1 0 7 7 7 4 PPR repeat family PPR_3 PF13812.6 KFX94827.1 - 9.5e-09 35.2 0.0 0.035 14.2 0.0 4.7 4 0 0 4 4 4 3 Pentatricopeptide repeat domain PPR PF01535.20 KFX94827.1 - 0.00069 19.7 10.3 1.2 9.5 0.0 6.7 9 0 0 9 9 9 2 PPR repeat ATP13 PF12921.7 KFX94827.1 - 0.0063 16.4 0.3 4.8 7.1 0.1 3.0 2 1 1 3 3 3 2 Mitochondrial ATPase expression Fungal_trans PF04082.18 KFX94832.1 - 1.6e-22 79.8 0.0 3e-22 78.9 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KFX94832.1 - 1.3e-09 38.0 6.1 2.4e-09 37.2 6.1 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ribosomal_60s PF00428.19 KFX94832.1 - 0.35 11.5 3.2 1.2 9.8 0.1 2.7 2 0 0 2 2 2 0 60s Acidic ribosomal protein Auxin_repressed PF05564.12 KFX94832.1 - 9.6 6.9 8.4 1.2 9.9 0.5 3.2 3 0 0 3 3 3 0 Dormancy/auxin associated protein Bap31 PF05529.12 KFX94833.1 - 9e-48 161.6 10.4 1.2e-47 161.1 10.4 1.2 1 0 0 1 1 1 1 Bap31/Bap29 transmembrane region Bap31_Bap29_C PF18035.1 KFX94833.1 - 2.7e-14 52.9 2.6 2.7e-14 52.9 2.6 1.7 2 0 0 2 2 2 1 Bap31/Bap29 cytoplasmic coiled-coil domain She9_MDM33 PF05546.11 KFX94833.1 - 0.0051 16.6 0.9 0.0051 16.6 0.9 1.6 2 0 0 2 2 2 1 She9 / Mdm33 family Filament PF00038.21 KFX94833.1 - 0.011 15.3 2.5 0.017 14.7 2.5 1.2 1 0 0 1 1 1 0 Intermediate filament protein DivIC PF04977.15 KFX94833.1 - 0.034 13.9 1.1 0.034 13.9 1.1 2.7 3 0 0 3 3 3 0 Septum formation initiator TMF_DNA_bd PF12329.8 KFX94833.1 - 0.054 13.5 5.3 0.047 13.7 3.8 1.6 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding DUF4349 PF14257.6 KFX94833.1 - 0.088 12.2 0.3 0.2 11.1 0.3 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4349) Spc7 PF08317.11 KFX94833.1 - 0.13 11.1 2.6 0.2 10.5 2.6 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein APG6_N PF17675.1 KFX94833.1 - 0.14 12.7 3.5 0.28 11.7 3.5 1.4 1 0 0 1 1 1 0 Apg6 coiled-coil region UPF0242 PF06785.11 KFX94833.1 - 0.46 10.6 4.8 0.078 13.1 0.4 1.8 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Csm1_N PF18504.1 KFX94833.1 - 0.47 10.8 4.8 0.38 11.1 2.6 1.9 1 1 1 2 2 2 0 Csm1 N-terminal domain Phage_GP20 PF06810.11 KFX94833.1 - 0.99 9.2 8.2 0.69 9.7 3.8 2.0 1 1 1 2 2 2 0 Phage minor structural protein GP20 PMT PF02366.18 KFX94839.1 - 2.1e-84 283.0 12.8 2.1e-84 283.0 12.8 1.7 2 0 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT_4TMC PF16192.5 KFX94839.1 - 9e-65 218.0 13.4 9e-65 218.0 13.4 2.0 2 0 0 2 2 2 1 C-terminal four TMM region of protein-O-mannosyltransferase MIR PF02815.19 KFX94839.1 - 1.1e-37 129.7 0.3 1.6e-37 129.2 0.3 1.2 1 0 0 1 1 1 1 MIR domain DUF2976 PF11190.8 KFX94839.1 - 0.084 12.7 0.3 2.1 8.2 0.4 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2976) Sugar_tr PF00083.24 KFX94840.1 - 2e-105 353.3 18.0 2.4e-105 353.0 18.0 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KFX94840.1 - 2e-32 112.5 41.5 1.3e-29 103.3 18.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 KFX94840.1 - 1.9e-06 26.7 23.0 4.6e-06 25.5 6.2 2.8 3 0 0 3 3 3 2 MFS/sugar transport protein MFS_5 PF05631.14 KFX94840.1 - 0.003 16.5 1.1 0.0052 15.7 1.1 1.3 1 0 0 1 1 1 1 Sugar-tranasporters, 12 TM MFS_1_like PF12832.7 KFX94840.1 - 0.013 14.4 7.1 0.14 10.9 0.1 2.5 2 1 0 2 2 2 0 MFS_1 like family MFS_3 PF05977.13 KFX94840.1 - 0.47 8.8 5.6 1 7.7 0.5 2.2 2 0 0 2 2 2 0 Transmembrane secretion effector Chs7 PF12271.8 KFX94841.1 - 1.3e-112 375.8 5.7 1.5e-112 375.7 5.7 1.0 1 0 0 1 1 1 1 Chitin synthase export chaperone DUF998 PF06197.13 KFX94841.1 - 0.011 15.4 12.2 0.016 14.8 1.0 2.6 2 2 0 2 2 2 0 Protein of unknown function (DUF998) YvrJ PF12841.7 KFX94841.1 - 0.018 14.6 0.0 0.04 13.4 0.0 1.5 1 0 0 1 1 1 0 YvrJ protein family Herpes_UL20 PF04544.12 KFX94841.1 - 0.13 12.6 0.1 0.13 12.6 0.1 1.9 2 1 0 2 2 2 0 Herpesvirus egress protein UL20 FixQ PF05545.11 KFX94841.1 - 0.3 11.1 4.8 4.3 7.4 0.0 3.5 3 0 0 3 3 3 0 Cbb3-type cytochrome oxidase component FixQ DUF202 PF02656.15 KFX94841.1 - 1.7 9.1 0.0 1.7 9.1 0.0 4.0 2 1 1 3 3 3 0 Domain of unknown function (DUF202) TssN PF17555.2 KFX94841.1 - 3.2 7.1 15.3 0.03 13.7 5.2 2.1 2 1 0 2 2 2 0 Type VI secretion system, TssN Ssl1 PF04056.14 KFX94842.1 - 3.8e-72 242.2 0.0 4.7e-72 241.8 0.0 1.1 1 0 0 1 1 1 1 Ssl1-like VWA_2 PF13519.6 KFX94842.1 - 2.3e-14 53.9 0.0 5.1e-14 52.8 0.0 1.6 2 0 0 2 2 2 1 von Willebrand factor type A domain Inhibitor_I9 PF05922.16 KFX94857.1 - 0.0046 17.6 0.1 0.005 17.5 0.1 1.2 1 0 0 1 1 1 1 Peptidase inhibitor I9 CFIA_Pcf11 PF11526.8 KFX94858.1 - 4.3e-09 36.7 0.4 1.1e-08 35.4 0.4 1.7 1 0 0 1 1 1 1 Subunit of cleavage factor IA Pcf11 CTD_bind PF04818.13 KFX94858.1 - 1.5e-05 25.7 0.0 4.7e-05 24.1 0.0 1.9 1 0 0 1 1 1 1 RNA polymerase II-binding domain. VHS PF00790.19 KFX94858.1 - 2.7e-05 24.0 0.0 5.9e-05 22.9 0.0 1.5 1 0 0 1 1 1 1 VHS domain zf-C2H2_4 PF13894.6 KFX94858.1 - 0.89 10.6 3.4 10 7.3 0.1 2.9 3 0 0 3 3 3 0 C2H2-type zinc finger zf_UBZ PF18439.1 KFX94858.1 - 0.98 9.1 8.3 1.3 8.7 3.6 2.8 2 1 0 2 2 2 0 Ubiquitin-Binding Zinc Finger Pil1 PF13805.6 KFX94859.1 - 7.6e-123 409.2 0.1 9.9e-123 408.8 0.1 1.1 1 0 0 1 1 1 1 Eisosome component PIL1 DUF2385 PF09539.10 KFX94859.1 - 0.12 12.9 0.2 5.5 7.6 0.0 3.1 4 0 0 4 4 4 0 Protein of unknown function (DUF2385) DUF3568 PF12092.8 KFX94859.1 - 0.14 12.2 0.0 0.42 10.7 0.0 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF3568) LSM PF01423.22 KFX94860.1 - 6e-08 32.3 0.0 7.7e-08 31.9 0.0 1.2 1 0 0 1 1 1 1 LSM domain XPG_N PF00752.17 KFX94861.1 - 7.1e-29 100.3 0.0 2.6e-28 98.4 0.0 2.0 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.18 KFX94861.1 - 5.9e-27 93.9 0.0 1.8e-26 92.3 0.0 1.9 1 0 0 1 1 1 1 XPG I-region UIM PF02809.20 KFX94861.1 - 0.0022 17.8 2.2 0.0022 17.8 2.2 3.2 3 0 0 3 3 3 1 Ubiquitin interaction motif 5_3_exonuc PF01367.20 KFX94861.1 - 0.0031 18.1 0.0 0.011 16.3 0.0 1.9 1 0 0 1 1 1 1 5'-3' exonuclease, C-terminal SAM fold DUF1943 PF09172.11 KFX94861.1 - 0.0098 15.2 0.1 0.022 14.0 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1943) Lipase_GDSL_2 PF13472.6 KFX94868.1 - 7.1e-08 33.0 0.8 8e-08 32.9 0.8 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 KFX94868.1 - 0.0016 18.5 0.2 0.0025 17.8 0.2 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Glyco_hydro_35 PF01301.19 KFX94869.1 - 7.2e-82 275.5 6.5 1.3e-81 274.7 6.5 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 BetaGal_dom4_5 PF13364.6 KFX94869.1 - 3.9e-56 188.5 0.5 8.4e-31 106.9 0.0 2.9 2 0 0 2 2 2 2 Beta-galactosidase jelly roll domain BetaGal_dom2 PF10435.9 KFX94869.1 - 6.7e-54 182.4 5.7 1.3e-53 181.5 5.7 1.5 1 0 0 1 1 1 1 Beta-galactosidase, domain 2 BetaGal_dom3 PF13363.6 KFX94869.1 - 6.5e-25 86.5 0.4 6.6e-24 83.3 0.6 2.3 2 0 0 2 2 2 1 Beta-galactosidase, domain 3 Pyr_redox_2 PF07992.14 KFX94870.1 - 2.6e-32 112.2 0.0 3.5e-32 111.8 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KFX94870.1 - 5.1e-11 43.0 0.2 2.8e-08 34.2 0.3 2.6 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KFX94870.1 - 1.2e-05 25.4 1.5 0.031 14.2 0.0 4.2 4 0 0 4 4 4 1 FAD-NAD(P)-binding Pyr_redox_3 PF13738.6 KFX94870.1 - 0.00022 20.6 0.0 0.00092 18.5 0.0 2.1 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KFX94870.1 - 0.00067 18.9 0.0 0.0039 16.4 0.0 1.9 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Trp_halogenase PF04820.14 KFX94870.1 - 0.035 13.0 0.3 6.1 5.6 0.1 2.3 2 0 0 2 2 2 0 Tryptophan halogenase DUF4232 PF14016.6 KFX94870.1 - 0.038 14.1 1.4 1.6 8.9 0.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF4232) DAO PF01266.24 KFX94870.1 - 0.072 12.7 3.0 42 3.5 0.1 3.7 4 0 0 4 4 4 0 FAD dependent oxidoreductase Abhydrolase_1 PF00561.20 KFX94870.1 - 0.15 11.7 0.4 0.28 10.8 0.4 1.6 1 1 0 1 1 1 0 alpha/beta hydrolase fold MFS_1 PF07690.16 KFX94871.1 - 1.4e-27 96.6 52.6 3.7e-15 55.7 34.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1072 PF06380.11 KFX94871.1 - 1.5 8.8 8.4 5.9 6.9 0.6 3.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1072) Fungal_trans PF04082.18 KFX94872.1 - 3.4e-15 55.8 0.0 4.9e-15 55.3 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KFX94872.1 - 4.3e-07 30.0 8.9 7.6e-07 29.1 8.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Dickkopf_N PF04706.12 KFX94872.1 - 4.1 8.0 13.4 4.6 7.8 10.0 2.4 3 0 0 3 3 3 0 Dickkopf N-terminal cysteine-rich region Cutinase PF01083.22 KFX94873.1 - 3.3e-48 164.0 2.8 4.2e-48 163.7 2.8 1.1 1 0 0 1 1 1 1 Cutinase PE-PPE PF08237.11 KFX94873.1 - 0.0021 17.6 0.1 0.0031 17.1 0.1 1.2 1 0 0 1 1 1 1 PE-PPE domain VirJ PF06057.11 KFX94873.1 - 0.0077 16.1 0.0 0.011 15.6 0.0 1.2 1 0 0 1 1 1 1 Bacterial virulence protein (VirJ) adh_short PF00106.25 KFX94875.1 - 5.3e-25 88.0 2.8 1e-21 77.3 2.8 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KFX94875.1 - 7.2e-14 51.9 3.1 8.8e-11 41.8 2.8 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KFX94875.1 - 8.2e-11 42.1 1.6 1.2e-10 41.6 1.6 1.2 1 0 0 1 1 1 1 KR domain Epiglycanin_C PF14654.6 KFX94876.1 - 0.087 12.9 0.0 0.14 12.3 0.0 1.3 1 0 0 1 1 1 0 Mucin, catalytic, TM and cytoplasmic tail region Sulfatase PF00884.23 KFX94886.1 - 4.8e-39 134.6 0.0 6.1e-39 134.2 0.0 1.1 1 0 0 1 1 1 1 Sulfatase Choline_sulf_C PF12411.8 KFX94886.1 - 7.7e-27 92.9 0.4 1.6e-26 91.8 0.4 1.6 1 0 0 1 1 1 1 Choline sulfatase enzyme C terminal DUF4976 PF16347.5 KFX94886.1 - 0.00022 21.4 0.0 0.00047 20.4 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4976) Phosphodiest PF01663.22 KFX94886.1 - 0.00073 19.2 0.0 0.00073 19.2 0.0 1.9 2 0 0 2 2 2 1 Type I phosphodiesterase / nucleotide pyrophosphatase REF PF05755.12 KFX94893.1 - 0.0035 17.2 0.1 0.004 17.0 0.1 1.0 1 0 0 1 1 1 1 Rubber elongation factor protein (REF) zf-C2H2 PF00096.26 KFX94905.1 - 6.3e-10 39.0 11.5 2.4e-05 24.6 4.5 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KFX94905.1 - 3.4e-09 36.7 12.5 5.1e-05 23.5 0.5 3.4 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 KFX94905.1 - 1e-06 29.1 11.0 0.0014 19.3 3.2 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf-met PF12874.7 KFX94905.1 - 7e-06 26.3 1.3 1.9e-05 24.9 1.3 1.8 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 KFX94905.1 - 0.00013 21.9 2.4 0.00013 21.9 2.4 2.5 2 0 0 2 2 2 1 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFX94905.1 - 0.00061 20.0 4.2 0.00079 19.6 1.8 2.2 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 KFX94905.1 - 0.061 13.7 1.2 0.061 13.7 1.2 1.8 2 1 0 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-C2H2_11 PF16622.5 KFX94905.1 - 0.13 12.1 8.2 1.3 8.8 1.1 2.7 2 0 0 2 2 2 0 zinc-finger C2H2-type zf-C2HC_2 PF13913.6 KFX94905.1 - 1 9.4 5.4 13 5.8 0.4 2.4 2 0 0 2 2 2 0 zinc-finger of a C2HC-type SF3b1 PF08920.10 KFX94906.1 - 2.7e-29 102.1 5.3 2.7e-29 102.1 5.3 2.1 2 1 0 2 2 1 1 Splicing factor 3B subunit 1 HEAT_EZ PF13513.6 KFX94906.1 - 3.5e-12 46.6 1.0 0.012 16.1 0.0 7.2 7 1 1 8 8 8 2 HEAT-like repeat HEAT_2 PF13646.6 KFX94906.1 - 3e-09 37.2 11.6 0.21 12.0 0.1 8.1 5 3 5 10 10 10 3 HEAT repeats HEAT PF02985.22 KFX94906.1 - 2.2e-07 30.5 10.2 1.5 9.3 0.1 9.1 10 0 0 10 10 10 2 HEAT repeat Vac14_Fab1_bd PF12755.7 KFX94906.1 - 0.00013 22.5 0.6 1.5 9.4 0.0 5.3 6 0 0 6 6 6 1 Vacuolar 14 Fab1-binding region Adaptin_N PF01602.20 KFX94906.1 - 0.00014 20.6 0.4 0.052 12.1 0.0 3.0 3 0 0 3 3 3 2 Adaptin N terminal region NUC173 PF08161.12 KFX94906.1 - 0.00043 20.0 0.4 1.2 8.7 0.0 4.1 4 1 0 5 5 5 2 NUC173 domain DUF3385 PF11865.8 KFX94906.1 - 0.0005 20.0 0.8 0.064 13.2 0.1 4.6 4 1 1 6 6 6 1 Domain of unknown function (DUF3385) UNC45-central PF11701.8 KFX94906.1 - 0.0044 17.0 0.0 0.014 15.4 0.0 1.8 2 0 0 2 2 2 1 Myosin-binding striated muscle assembly central CLASP_N PF12348.8 KFX94906.1 - 0.011 15.4 0.0 0.91 9.0 0.0 3.3 3 0 0 3 3 3 0 CLASP N terminal DRIM PF07539.12 KFX94906.1 - 0.091 11.0 0.1 4.8 5.4 0.0 3.4 2 1 1 3 3 3 0 Down-regulated in metastasis MMS19_C PF12460.8 KFX94906.1 - 0.14 11.3 0.0 9.8 5.2 0.0 3.2 3 1 0 3 3 3 0 RNAPII transcription regulator C-terminal Hva1_TUDOR PF11160.8 KFX94913.1 - 1.5e-14 53.9 0.8 2.8e-14 53.0 0.1 1.9 2 0 0 2 2 2 1 Hypervirulence associated proteins TUDOR domain FAD_binding_3 PF01494.19 KFX94915.1 - 3.4e-19 69.3 0.0 7.3e-19 68.2 0.0 1.5 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 KFX94915.1 - 1.6e-06 27.6 0.0 3.8e-06 26.4 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KFX94915.1 - 5.1e-05 23.4 0.1 0.00014 22.0 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 KFX94915.1 - 0.0011 17.7 0.1 0.0017 17.1 0.1 1.2 1 0 0 1 1 1 1 HI0933-like protein DAO PF01266.24 KFX94915.1 - 0.0024 17.5 0.4 0.013 15.1 0.4 2.3 2 1 1 3 3 3 1 FAD dependent oxidoreductase GIDA PF01134.22 KFX94915.1 - 0.0032 16.6 0.0 0.0057 15.8 0.0 1.4 1 1 0 1 1 1 1 Glucose inhibited division protein A Pyr_redox PF00070.27 KFX94915.1 - 0.0072 16.9 0.0 0.024 15.2 0.0 1.9 2 0 0 2 2 1 1 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 KFX94915.1 - 0.012 14.9 0.0 0.021 14.2 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain 3HCDH_N PF02737.18 KFX94915.1 - 0.023 14.6 0.0 0.036 13.9 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_oxidored PF12831.7 KFX94915.1 - 0.043 13.2 0.2 0.08 12.3 0.2 1.5 1 0 0 1 1 1 0 FAD dependent oxidoreductase Trp_halogenase PF04820.14 KFX94915.1 - 0.065 12.1 0.1 7 5.4 0.1 2.3 2 0 0 2 2 2 0 Tryptophan halogenase SE PF08491.10 KFX94915.1 - 0.082 11.9 0.0 0.14 11.1 0.0 1.3 1 0 0 1 1 1 0 Squalene epoxidase Thi4 PF01946.17 KFX94915.1 - 0.2 10.9 0.0 0.38 10.0 0.0 1.3 1 0 0 1 1 1 0 Thi4 family Peptidase_M24 PF00557.24 KFX94916.1 - 6.6e-47 159.9 0.1 8e-47 159.6 0.1 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 zf-C6H2 PF15801.5 KFX94916.1 - 5e-21 74.7 8.7 1e-20 73.7 8.7 1.6 1 0 0 1 1 1 1 zf-MYND-like zinc finger, mRNA-binding zf-MYND PF01753.18 KFX94916.1 - 3.3e-05 23.9 4.4 8.7e-05 22.5 4.4 1.8 1 0 0 1 1 1 1 MYND finger ApbA_C PF08546.11 KFX94916.1 - 0.098 12.9 0.0 0.19 11.9 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA C terminal zf-HIT PF04438.16 KFX94916.1 - 0.35 10.8 3.0 0.85 9.5 3.0 1.7 1 0 0 1 1 1 0 HIT zinc finger Cornichon PF03311.14 KFX94917.1 - 1.3e-50 170.8 12.4 1.5e-50 170.6 12.4 1.0 1 0 0 1 1 1 1 Cornichon protein WD40 PF00400.32 KFX94918.1 - 2.4e-28 97.8 4.4 2.7e-06 28.0 0.2 6.6 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFX94918.1 - 4.1e-12 46.2 0.4 0.00015 22.0 0.2 4.7 3 2 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KFX94918.1 - 0.062 11.9 0.4 2 6.9 0.0 2.4 1 1 1 2 2 2 0 Nucleoporin Nup120/160 CR6_interact PF10147.9 KFX94919.1 - 0.014 15.1 1.4 0.023 14.4 1.4 1.2 1 0 0 1 1 1 0 Growth arrest and DNA-damage-inducible proteins-interacting protein 1 Glyco_hydro_32N PF00251.20 KFX94928.1 - 2.7e-37 129.0 0.0 5e-37 128.1 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 N-terminal domain Glyco_hydro_32C PF08244.12 KFX94928.1 - 2.4e-25 89.4 0.0 3.6e-25 88.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 C terminal Glyco_hydro_43 PF04616.14 KFX94928.1 - 0.14 11.4 0.0 2.5 7.3 0.0 2.5 1 1 2 3 3 3 0 Glycosyl hydrolases family 43 DUF4975 PF16346.5 KFX94928.1 - 0.17 11.9 0.0 0.28 11.2 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4975) RNA_pol_3_Rpc31 PF11705.8 KFX94930.1 - 3.7e-58 197.5 4.0 3.7e-58 197.5 4.0 1.3 2 0 0 2 2 2 1 DNA-directed RNA polymerase III subunit Rpc31 TFIIA PF03153.13 KFX94930.1 - 0.11 12.4 2.0 0.097 12.7 2.0 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Fungal_trans PF04082.18 KFX94943.1 - 3e-12 46.1 0.5 5.6e-12 45.2 0.3 1.4 1 1 0 1 1 1 1 Fungal specific transcription factor domain RBR PF17208.3 KFX94943.1 - 0.0022 18.7 0.5 0.0051 17.5 0.5 1.7 1 0 0 1 1 1 1 RNA binding Region zf-RING_UBOX PF13445.6 KFX94943.1 - 0.33 11.0 1.8 0.71 10.0 1.8 1.5 1 0 0 1 1 1 0 RING-type zinc-finger DAO PF01266.24 KFX94949.1 - 1.8e-59 202.1 0.7 3.5e-59 201.2 0.7 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_4 PF01565.23 KFX94949.1 - 5.1e-23 81.3 0.7 2.3e-21 76.0 0.2 3.0 3 0 0 3 3 2 1 FAD binding domain Cellulase PF00150.18 KFX94949.1 - 7.4e-16 58.4 2.9 1.7e-15 57.2 2.9 1.6 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) BBE PF08031.12 KFX94949.1 - 8.8e-12 44.9 0.0 2e-11 43.8 0.0 1.6 1 0 0 1 1 1 1 Berberine and berberine like Pyr_redox_2 PF07992.14 KFX94949.1 - 8.6e-05 21.9 0.1 0.067 12.4 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KFX94949.1 - 0.00021 21.5 0.6 0.0051 17.0 0.1 2.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 KFX94949.1 - 0.00055 20.5 0.0 0.055 14.0 0.0 2.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Glyco_hydro_42 PF02449.15 KFX94949.1 - 0.0011 18.3 0.0 0.0036 16.7 0.0 1.7 1 1 0 1 1 1 1 Beta-galactosidase Mqo PF06039.15 KFX94949.1 - 0.0018 16.9 0.1 0.079 11.5 0.0 2.1 2 0 0 2 2 2 1 Malate:quinone oxidoreductase (Mqo) FAD_binding_2 PF00890.24 KFX94949.1 - 0.0068 15.5 1.1 0.019 14.1 1.1 1.7 1 1 0 1 1 1 1 FAD binding domain Glyco_hydro_2_C PF02836.17 KFX94949.1 - 0.0069 15.5 0.0 0.022 13.9 0.0 1.8 2 0 0 2 2 2 1 Glycosyl hydrolases family 2, TIM barrel domain GMC_oxred_N PF00732.19 KFX94949.1 - 0.059 12.7 0.0 0.54 9.6 0.0 2.2 2 0 0 2 2 2 0 GMC oxidoreductase Thi4 PF01946.17 KFX94949.1 - 0.16 11.2 0.3 0.6 9.3 0.2 2.0 2 0 0 2 2 2 0 Thi4 family MCRA PF06100.11 KFX94949.1 - 0.65 8.7 7.1 0.068 12.0 0.3 2.5 3 0 0 3 3 3 0 MCRA family T5orf172 PF10544.9 KFX94952.1 - 2.8e-11 43.8 0.8 6.1e-11 42.8 0.8 1.5 1 0 0 1 1 1 1 T5orf172 domain MUG113 PF13455.6 KFX94952.1 - 1.4e-08 35.3 1.0 3.7e-08 33.9 1.0 1.7 1 0 0 1 1 1 1 Meiotically up-regulated gene 113 DUF2457 PF10446.9 KFX94952.1 - 0.013 14.7 14.1 0.019 14.1 14.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) BUD22 PF09073.10 KFX94952.1 - 0.15 11.4 15.5 0.23 10.8 15.5 1.2 1 0 0 1 1 1 0 BUD22 RNA_pol_3_Rpc31 PF11705.8 KFX94952.1 - 0.24 11.6 14.4 0.56 10.4 14.4 1.6 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 SDA1 PF05285.12 KFX94952.1 - 0.3 10.5 12.8 0.47 9.8 12.8 1.2 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.12 KFX94952.1 - 0.4 8.8 12.8 0.52 8.5 12.8 1.1 1 0 0 1 1 1 0 Nop14-like family TEX19 PF15553.6 KFX94952.1 - 3.8 7.5 5.7 7.5 6.5 5.7 1.4 1 0 0 1 1 1 0 Testis-expressed protein 19 CDC45 PF02724.14 KFX94952.1 - 5.6 5.1 10.0 7.5 4.7 10.0 1.1 1 0 0 1 1 1 0 CDC45-like protein Amidohydro_1 PF01979.20 KFX94953.1 - 5.9e-10 39.0 0.0 2.6e-09 36.9 0.0 1.9 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 KFX94953.1 - 1.6e-08 34.5 0.9 2.7e-07 30.4 0.0 2.2 2 0 0 2 2 2 1 Amidohydrolase family Abhydrolase_6 PF12697.7 KFX94953.1 - 1.1e-05 26.2 2.5 1.3e-05 25.9 0.2 2.0 2 0 0 2 2 2 1 Alpha/beta hydrolase family NDT80_PhoG PF05224.12 KFX94954.1 - 1.8e-31 109.8 0.0 2.8e-31 109.2 0.0 1.3 1 0 0 1 1 1 1 NDT80 / PhoG like DNA-binding family KH_1 PF00013.29 KFX94955.1 - 5.3e-41 138.3 12.0 6.4e-17 61.1 0.1 3.3 3 0 0 3 3 3 3 KH domain KH_2 PF07650.17 KFX94955.1 - 1.7e-10 40.6 8.3 0.006 16.4 0.3 3.3 3 0 0 3 3 3 3 KH domain KH_4 PF13083.6 KFX94955.1 - 2.2e-07 30.6 7.8 0.025 14.5 0.3 3.6 4 0 0 4 4 4 3 KH domain KH_5 PF13184.6 KFX94955.1 - 6e-05 23.0 5.7 0.12 12.4 0.1 3.4 3 0 0 3 3 3 2 NusA-like KH domain ECF-ribofla_trS PF07155.12 KFX94955.1 - 0.045 13.8 0.3 0.08 12.9 0.3 1.3 1 0 0 1 1 1 0 ECF-type riboflavin transporter, S component MOEP19 PF16005.5 KFX94955.1 - 0.061 13.3 0.0 15 5.7 0.0 2.4 2 0 0 2 2 2 0 KH-like RNA-binding domain Ank_2 PF12796.7 KFX94958.1 - 6.7e-44 148.4 25.9 3.9e-15 56.2 2.1 4.7 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KFX94958.1 - 1.6e-32 111.5 1.4 1.8e-09 37.9 0.1 6.6 4 2 4 8 8 8 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFX94958.1 - 1.6e-28 95.6 4.9 0.0002 21.5 0.0 8.1 8 0 0 8 8 8 6 Ankyrin repeat Ank PF00023.30 KFX94958.1 - 2e-27 94.4 20.6 1.1e-05 25.6 0.4 8.1 8 0 0 8 8 8 6 Ankyrin repeat Ank_5 PF13857.6 KFX94958.1 - 4.7e-13 49.1 7.6 0.0015 18.8 0.2 6.1 3 1 4 7 7 7 4 Ankyrin repeats (many copies) Borealin PF10512.9 KFX94958.1 - 0.014 15.3 0.0 3.5 7.6 0.0 3.6 2 1 2 4 4 4 0 Cell division cycle-associated protein 8 DUF1843 PF08898.10 KFX94958.1 - 0.046 14.2 6.9 2.6 8.6 0.1 4.4 5 0 0 5 5 5 0 Domain of unknown function (DUF1843) ALF PF03752.13 KFX94958.1 - 0.096 12.7 0.1 3 7.9 0.0 3.6 2 0 0 2 2 2 0 Short repeats of unknown function Glyco_hydro_26 PF02156.15 KFX94960.1 - 0.056 12.9 0.1 0.19 11.1 0.0 2.0 3 0 0 3 3 3 0 Glycosyl hydrolase family 26 MAGE_N PF12440.8 KFX94960.1 - 2.6 8.8 12.6 12 6.6 0.2 2.3 2 0 0 2 2 2 0 Melanoma associated antigen family N terminal Ferritin_2 PF13668.6 KFX94961.1 - 2.2e-18 66.8 0.3 3.2e-18 66.2 0.3 1.2 1 0 0 1 1 1 1 Ferritin-like domain Transketolase_N PF00456.21 KFX94961.1 - 0.018 14.0 0.1 0.025 13.5 0.1 1.1 1 0 0 1 1 1 0 Transketolase, thiamine diphosphate binding domain SHE3 PF17078.5 KFX94962.1 - 0.0076 16.0 0.6 0.26 11.0 0.2 2.0 1 1 1 2 2 2 2 SWI5-dependent HO expression protein 3 DUF848 PF05852.11 KFX94962.1 - 0.012 15.7 0.2 0.02 15.0 0.2 1.4 1 1 0 1 1 1 0 Gammaherpesvirus protein of unknown function (DUF848) DivIC PF04977.15 KFX94962.1 - 0.071 12.9 0.1 0.11 12.3 0.1 1.3 1 0 0 1 1 1 0 Septum formation initiator ZapB PF06005.12 KFX94962.1 - 0.091 13.2 0.4 0.17 12.3 0.4 1.5 1 0 0 1 1 1 0 Cell division protein ZapB DUF4101 PF13355.6 KFX94963.1 - 0.16 12.4 4.8 0.29 11.6 4.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4101) Gastrin PF00918.17 KFX94963.1 - 2.6 9.0 5.6 0.78 10.7 0.9 2.0 1 1 1 2 2 2 0 Gastrin/cholecystokinin family Acetyltransf_3 PF13302.7 KFX94965.1 - 6.1e-11 43.2 0.0 8.9e-11 42.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KFX94965.1 - 0.0067 16.7 0.0 0.01 16.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family WLM PF08325.10 KFX94966.1 - 3.2e-45 154.5 0.0 4.5e-45 154.1 0.0 1.4 1 1 0 1 1 1 1 WLM domain zf-RanBP PF00641.18 KFX94966.1 - 8.7e-09 34.6 11.1 5.7e-08 31.9 0.8 2.4 2 0 0 2 2 2 2 Zn-finger in Ran binding protein and others DUF45 PF01863.17 KFX94966.1 - 0.066 13.3 0.3 0.12 12.4 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function DUF45 HutP PF09021.11 KFX94966.1 - 0.072 13.4 0.7 0.12 12.7 0.7 1.3 1 0 0 1 1 1 0 HutP Mut7-C PF01927.16 KFX94966.1 - 0.11 12.6 0.5 0.21 11.7 0.5 1.4 1 0 0 1 1 1 0 Mut7-C RNAse domain DUF1776 PF08643.10 KFX94967.1 - 9e-84 281.3 0.0 1.1e-83 281.0 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) adh_short PF00106.25 KFX94967.1 - 0.0041 16.6 0.0 3.6 7.0 0.0 2.8 2 1 0 2 2 2 2 short chain dehydrogenase MBOAT PF03062.19 KFX94968.1 - 1.3e-46 159.6 18.3 2.2e-46 158.9 18.3 1.3 1 0 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family Actin PF00022.19 KFX94969.1 - 1.6e-140 468.3 0.0 1.8e-140 468.1 0.0 1.0 1 0 0 1 1 1 1 Actin MreB_Mbl PF06723.13 KFX94969.1 - 0.034 12.9 0.0 6 5.6 0.0 2.7 3 0 0 3 3 3 0 MreB/Mbl protein SPX PF03105.19 KFX94977.1 - 3.1 7.6 8.6 3.2 7.6 8.6 1.0 1 0 0 1 1 1 0 SPX domain Ndc1_Nup PF09531.10 KFX94977.1 - 7.2 5.2 6.8 7.9 5.0 6.8 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Sec23_trunk PF04811.15 KFX94978.1 - 4e-54 183.8 0.0 3.1e-53 180.8 0.0 2.2 2 1 0 2 2 2 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.15 KFX94978.1 - 5.8e-25 87.1 0.0 1.1e-24 86.2 0.0 1.5 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Sec23_BS PF08033.12 KFX94978.1 - 3.1e-17 63.1 0.0 5.3e-17 62.3 0.0 1.4 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.15 KFX94978.1 - 3.9e-15 55.6 5.6 1.1e-14 54.2 5.6 1.8 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.22 KFX94978.1 - 1.1e-07 31.7 0.0 2.3e-07 30.6 0.0 1.6 1 0 0 1 1 1 1 Gelsolin repeat DUF1590 PF07629.11 KFX94978.1 - 0.03 14.1 1.7 0.11 12.3 0.6 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1590) Vg_Tdu PF07545.14 KFX94978.1 - 0.12 12.2 0.0 0.25 11.1 0.0 1.5 1 0 0 1 1 1 0 Vestigial/Tondu family Lactamase_B_6 PF16661.5 KFX94979.1 - 4.8e-68 228.4 0.0 7.7e-68 227.7 0.0 1.3 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily domain CPSF100_C PF13299.6 KFX94979.1 - 2.5e-49 167.7 0.0 2.5e-49 167.7 0.0 2.1 3 0 0 3 3 3 1 Cleavage and polyadenylation factor 2 C-terminal Beta-Casp PF10996.8 KFX94979.1 - 2.8e-17 63.0 0.0 1.4e-16 60.7 0.0 2.2 2 0 0 2 2 2 1 Beta-Casp domain RMMBL PF07521.12 KFX94979.1 - 7.4e-12 45.0 0.0 1.6e-11 44.0 0.0 1.6 1 0 0 1 1 1 1 Zn-dependent metallo-hydrolase RNA specificity domain Lactamase_B_2 PF12706.7 KFX94979.1 - 0.0066 16.0 0.2 0.045 13.2 0.2 2.1 2 0 0 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 KFX94979.1 - 0.034 14.2 0.0 0.078 13.0 0.0 1.6 1 0 0 1 1 1 0 Metallo-beta-lactamase superfamily Bestrophin PF01062.21 KFX94983.1 - 8.7e-39 133.7 0.0 1.3e-38 133.0 0.0 1.2 1 0 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel Myb_DNA-bind_6 PF13921.6 KFX94986.1 - 3.1e-05 24.1 0.2 3.1e-05 24.1 0.2 1.9 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 KFX94986.1 - 0.032 14.4 0.0 0.071 13.3 0.0 1.6 1 0 0 1 1 1 0 Myb-like DNA-binding domain MG3 PF17791.1 KFX94986.1 - 0.058 13.7 0.0 2.3 8.5 0.0 2.4 2 0 0 2 2 2 0 Macroglobulin domain MG3 Beta-lactamase PF00144.24 KFX94989.1 - 7.8e-44 150.3 0.0 1.2e-43 149.7 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase WD40 PF00400.32 KFX94990.1 - 2.2e-49 164.4 13.3 5.8e-09 36.4 0.0 7.5 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFX94990.1 - 3.6e-22 78.5 0.0 0.00082 19.6 0.0 6.8 2 1 5 7 7 7 5 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 KFX94990.1 - 2.2e-17 62.5 6.7 0.18 11.8 0.0 7.4 7 0 0 7 7 7 7 WD40-like Beta Propeller Repeat Ge1_WD40 PF16529.5 KFX94990.1 - 6.1e-12 45.1 3.5 0.028 13.4 0.0 6.3 3 2 4 7 7 7 4 WD40 region of Ge1, enhancer of mRNA-decapping protein Proteasome_A_N PF10584.9 KFX94990.1 - 8.8e-09 34.9 6.3 6 6.6 0.0 8.1 8 0 0 8 8 8 2 Proteasome subunit A N-terminal signature eIF2A PF08662.11 KFX94990.1 - 1.8e-08 34.5 0.0 8.5e-05 22.5 0.0 2.6 2 1 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A Nbas_N PF15492.6 KFX94990.1 - 2.9e-05 23.5 2.0 1.7 7.9 0.0 5.0 1 1 3 5 5 5 1 Neuroblastoma-amplified sequence, N terminal Ret2_MD PF18528.1 KFX94990.1 - 3.9e-05 23.9 0.0 8.6 6.8 0.0 5.5 5 2 2 7 7 7 1 RNA editing 3' terminal uridylyl transferase 2 middle domain GspH PF12019.8 KFX94990.1 - 0.00014 22.2 0.5 3.4 8.1 0.0 4.6 1 1 4 5 5 5 1 Type II transport protein GspH PQQ_2 PF13360.6 KFX94990.1 - 0.0019 17.8 0.6 0.42 10.1 0.0 2.7 1 1 1 3 3 3 1 PQQ-like domain DPPIV_N PF00930.21 KFX94990.1 - 0.0021 16.9 0.0 0.69 8.6 0.0 3.9 3 1 1 5 5 5 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Nup160 PF11715.8 KFX94990.1 - 0.0053 15.5 0.0 0.14 10.8 0.0 2.6 3 0 0 3 3 3 1 Nucleoporin Nup120/160 Zn_clus PF00172.18 KFX94990.1 - 0.0058 16.7 15.6 0.016 15.3 15.6 1.8 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Cytochrom_D1 PF02239.16 KFX94990.1 - 0.0099 14.4 0.0 0.36 9.3 0.0 2.6 2 1 0 3 3 3 1 Cytochrome D1 heme domain RAB3GAP2_N PF14655.6 KFX94990.1 - 0.07 12.4 0.2 24 4.0 0.0 3.2 3 0 0 3 3 3 0 Rab3 GTPase-activating protein regulatory subunit N-terminus TruB_C PF09142.11 KFX94990.1 - 0.081 12.7 1.5 1.6e+02 2.2 0.0 5.0 6 0 0 6 6 6 0 tRNA Pseudouridine synthase II, C terminal TFIIIC_delta PF12657.7 KFX94990.1 - 0.094 12.6 1.0 55 3.6 0.1 4.4 3 2 1 4 4 4 0 Transcription factor IIIC subunit delta N-term MFS_1 PF07690.16 KFX94992.1 - 6e-42 143.8 54.9 1.3e-41 142.8 53.1 2.3 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 KFX94992.1 - 1.2e-14 53.7 20.2 2e-14 52.9 20.2 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) NACHT PF05729.12 KFX94993.1 - 1.4e-08 34.8 1.7 1e-07 32.0 0.9 2.7 2 1 0 2 2 2 1 NACHT domain AAA_16 PF13191.6 KFX94993.1 - 3.5e-05 24.3 2.0 9.5e-05 22.8 0.0 2.8 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 KFX94993.1 - 9.9e-05 22.6 0.0 0.00059 20.1 0.0 2.3 2 0 0 2 2 2 1 AAA domain NB-ARC PF00931.22 KFX94993.1 - 0.013 14.7 0.0 0.58 9.3 0.0 2.5 2 0 0 2 2 2 0 NB-ARC domain RNA_helicase PF00910.22 KFX94993.1 - 0.017 15.5 0.0 0.06 13.7 0.0 2.0 1 0 0 1 1 1 0 RNA helicase AAA_18 PF13238.6 KFX94993.1 - 0.018 15.6 0.1 0.11 13.1 0.0 2.4 3 0 0 3 3 3 0 AAA domain MMR_HSR1 PF01926.23 KFX94993.1 - 0.034 14.2 0.0 0.19 11.8 0.0 2.3 2 0 0 2 2 2 0 50S ribosome-binding GTPase Viral_helicase1 PF01443.18 KFX94993.1 - 0.035 13.8 0.0 0.13 12.0 0.0 2.0 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_29 PF13555.6 KFX94993.1 - 0.091 12.5 0.2 0.28 11.0 0.2 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain RIH_assoc PF08454.11 KFX94993.1 - 4.4 7.2 8.1 7.2 6.5 1.7 3.2 2 1 1 3 3 3 0 RyR and IP3R Homology associated zf-C2H2 PF00096.26 KFX94994.1 - 1.5e-12 47.2 11.0 1.3e-05 25.4 0.1 3.1 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFX94994.1 - 1.8e-10 40.7 6.3 0.0003 21.4 2.0 2.5 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KFX94994.1 - 5.8e-09 36.0 9.0 4e-06 27.0 0.8 3.2 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_jaz PF12171.8 KFX94994.1 - 1.6e-05 25.0 0.8 0.18 12.2 0.0 2.5 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KFX94994.1 - 0.0001 22.5 1.6 0.57 10.6 0.0 2.6 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 KFX94994.1 - 0.00014 21.8 3.6 0.15 12.1 0.2 2.4 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_11 PF16622.5 KFX94994.1 - 0.011 15.5 1.1 2.4 8.0 0.0 2.4 2 0 0 2 2 2 0 zinc-finger C2H2-type C5HCH PF17982.1 KFX94994.1 - 0.04 14.1 0.5 0.04 14.1 0.5 2.3 1 1 1 2 2 2 0 NSD Cys-His rich domain BolA PF01722.18 KFX94994.1 - 0.047 14.0 0.1 2.5 8.4 0.0 2.4 2 1 1 3 3 3 0 BolA-like protein zf-H2C2_5 PF13909.6 KFX94994.1 - 0.17 11.7 8.5 0.83 9.5 0.0 2.7 2 1 0 2 2 2 0 C2H2-type zinc-finger domain zf-LYAR PF08790.11 KFX94994.1 - 0.27 11.2 1.4 7.2 6.6 0.0 2.4 2 0 0 2 2 2 0 LYAR-type C2HC zinc finger zf-C2HE PF16278.5 KFX94994.1 - 0.41 11.1 6.1 2.8 8.5 1.5 2.3 1 1 1 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger Sulfotransfer_4 PF17784.1 KFX95003.1 - 6e-44 150.4 0.0 7.9e-44 150.0 0.0 1.1 1 0 0 1 1 1 1 Sulfotransferase domain DHC_N1 PF08385.12 KFX95004.1 - 2.4e-127 426.0 7.3 2.4e-127 426.0 7.3 4.5 4 0 0 4 4 4 1 Dynein heavy chain, N-terminal region 1 AAA_6 PF12774.7 KFX95004.1 - 2.3e-126 421.2 0.0 9.4e-126 419.2 0.0 2.2 2 0 0 2 2 1 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 KFX95004.1 - 7.8e-114 380.9 6.3 7.8e-114 380.9 6.3 5.6 4 2 1 5 5 4 1 Dynein heavy chain, N-terminal region 2 AAA_9 PF12781.7 KFX95004.1 - 1e-73 247.1 1.2 1e-73 247.1 1.2 4.5 5 0 0 5 5 4 1 ATP-binding dynein motor region AAA_8 PF12780.7 KFX95004.1 - 4.5e-67 226.1 0.0 3.8e-66 223.1 0.0 2.5 2 0 0 2 2 2 1 P-loop containing dynein motor region D4 AAA_7 PF12775.7 KFX95004.1 - 2.1e-42 144.7 0.0 2e-35 122.0 0.0 5.1 4 0 0 4 4 4 2 P-loop containing dynein motor region MT PF12777.7 KFX95004.1 - 3.3e-36 125.0 6.3 3.3e-36 125.0 6.3 2.0 2 0 0 2 2 2 1 Microtubule-binding stalk of dynein motor AAA_5 PF07728.14 KFX95004.1 - 6.5e-32 110.4 0.9 1.6e-11 44.4 0.0 7.1 5 1 0 5 5 5 4 AAA domain (dynein-related subfamily) Dynein_heavy PF03028.15 KFX95004.1 - 1.7e-29 102.4 3.2 1e-27 96.6 0.0 4.6 5 0 0 5 5 4 1 Dynein heavy chain region D6 P-loop domain AAA_lid_11 PF18198.1 KFX95004.1 - 6.2e-28 97.7 0.0 1.7e-27 96.3 0.0 1.8 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain AAA_22 PF13401.6 KFX95004.1 - 1.9e-15 57.3 0.1 0.0095 16.2 0.0 6.3 5 0 0 5 5 4 3 AAA domain Dynein_AAA_lid PF17852.1 KFX95004.1 - 2.7e-15 56.6 0.9 7.4e-15 55.2 0.0 2.3 2 0 0 2 2 1 1 Dynein heavy chain AAA lid domain AAA PF00004.29 KFX95004.1 - 5.8e-14 52.6 0.0 0.0043 17.5 0.0 5.1 4 0 0 4 4 4 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KFX95004.1 - 4.4e-10 40.2 0.0 1.8 8.9 0.0 7.1 5 0 0 5 5 5 2 AAA ATPase domain AAA_18 PF13238.6 KFX95004.1 - 1.1e-09 39.0 1.0 0.018 15.6 0.0 5.7 5 0 0 5 5 4 2 AAA domain AAA_33 PF13671.6 KFX95004.1 - 1.2e-08 35.2 9.2 0.024 14.8 0.0 5.6 6 0 0 6 6 4 3 AAA domain T2SSE PF00437.20 KFX95004.1 - 9.3e-08 31.5 0.0 0.019 14.0 0.0 3.8 3 0 0 3 3 3 2 Type II/IV secretion system protein AAA_19 PF13245.6 KFX95004.1 - 6e-05 23.4 1.5 0.28 11.5 0.0 4.8 4 0 0 4 4 4 1 AAA domain Mg_chelatase PF01078.21 KFX95004.1 - 0.00011 21.6 4.4 0.67 9.3 0.0 4.8 5 0 0 5 5 4 1 Magnesium chelatase, subunit ChlI FtsK_SpoIIIE PF01580.18 KFX95004.1 - 0.00026 20.4 0.0 2.4 7.5 0.0 3.9 3 0 0 3 3 3 1 FtsK/SpoIIIE family AAA_lid_1 PF17857.1 KFX95004.1 - 0.00027 21.1 0.2 0.0022 18.2 0.0 2.8 2 0 0 2 2 1 1 AAA+ lid domain AAA_29 PF13555.6 KFX95004.1 - 0.00031 20.4 0.1 2.3 8.0 0.0 3.7 3 0 0 3 3 3 1 P-loop containing region of AAA domain AAA_30 PF13604.6 KFX95004.1 - 0.00098 18.9 3.8 34 4.1 0.0 5.1 5 0 0 5 5 5 0 AAA domain AAA_24 PF13479.6 KFX95004.1 - 0.0013 18.5 0.1 11 5.7 0.0 4.6 4 0 0 4 4 4 0 AAA domain ABC_tran PF00005.27 KFX95004.1 - 0.0013 19.2 4.9 4.3 7.9 0.0 5.1 4 0 0 4 4 3 0 ABC transporter AAA_25 PF13481.6 KFX95004.1 - 0.0017 18.0 1.0 0.26 10.8 0.0 3.7 3 0 0 3 3 2 1 AAA domain IstB_IS21 PF01695.17 KFX95004.1 - 0.0039 16.9 1.2 0.71 9.6 0.0 4.4 5 0 0 5 5 4 1 IstB-like ATP binding protein RNA_helicase PF00910.22 KFX95004.1 - 0.0088 16.4 0.1 52 4.3 0.0 4.8 4 0 0 4 4 4 0 RNA helicase Rad17 PF03215.15 KFX95004.1 - 0.017 15.1 0.2 6.8 6.6 0.0 4.2 5 0 0 5 5 4 0 Rad17 P-loop domain Zeta_toxin PF06414.12 KFX95004.1 - 0.021 14.1 0.6 17 4.6 0.1 4.3 4 0 0 4 4 4 0 Zeta toxin Pox_A32 PF04665.12 KFX95004.1 - 0.047 13.2 0.6 24 4.3 0.0 3.8 4 0 0 4 4 3 0 Poxvirus A32 protein PduV-EutP PF10662.9 KFX95004.1 - 0.052 13.3 0.4 11 5.7 0.1 3.6 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation AAA_21 PF13304.6 KFX95004.1 - 0.063 13.1 0.2 9.4 5.9 0.0 3.3 3 0 0 3 3 3 0 AAA domain, putative AbiEii toxin, Type IV TA system MobB PF03205.14 KFX95004.1 - 0.085 12.8 0.1 9.1 6.2 0.0 2.9 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B NTPase_1 PF03266.15 KFX95004.1 - 0.13 12.2 0.1 46 3.9 0.0 3.7 3 0 0 3 3 3 0 NTPase Hemerythrin PF01814.23 KFX95004.1 - 0.14 12.8 1.1 5.5 7.6 0.1 4.0 3 0 0 3 3 2 0 Hemerythrin HHE cation binding domain NACHT PF05729.12 KFX95004.1 - 0.18 11.7 9.9 31 4.4 0.0 5.7 5 0 0 5 5 4 0 NACHT domain TsaE PF02367.17 KFX95004.1 - 0.2 11.7 4.5 22 5.1 0.0 4.2 5 0 0 5 5 4 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE DUF4482 PF14818.6 KFX95004.1 - 0.36 11.7 9.4 30 5.5 0.0 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4482) ING PF12998.7 KFX95004.1 - 0.49 11.0 5.8 8.9 7.0 0.0 4.5 3 0 0 3 3 2 0 Inhibitor of growth proteins N-terminal histone-binding SRP54 PF00448.22 KFX95004.1 - 0.5 10.0 3.2 56 3.3 0.1 4.2 4 0 0 4 4 4 0 SRP54-type protein, GTPase domain DUF3867 PF12983.7 KFX95004.1 - 0.79 9.7 10.8 1.4 8.9 0.1 3.4 4 0 0 4 4 2 0 Protein of unknown function (DUF3867) Phage_GP20 PF06810.11 KFX95004.1 - 0.91 9.3 19.3 1.6 8.5 7.3 3.9 3 0 0 3 3 3 0 Phage minor structural protein GP20 ERM PF00769.19 KFX95004.1 - 1.5 8.5 25.5 0.9 9.3 1.7 3.6 3 0 0 3 3 3 0 Ezrin/radixin/moesin family MbeB_N PF04837.12 KFX95004.1 - 5.6 7.4 9.8 2.6 8.4 0.1 4.3 3 0 0 3 3 3 0 MbeB-like, N-term conserved region MAS20 PF02064.15 KFX95005.1 - 1.2e-47 161.2 1.0 1.4e-47 161.0 1.0 1.0 1 0 0 1 1 1 1 MAS20 protein import receptor Nif11 PF07862.11 KFX95005.1 - 0.0055 17.0 1.0 0.13 12.6 1.0 2.5 1 1 0 1 1 1 1 Nif11 domain TetR_C_36 PF18598.1 KFX95005.1 - 0.067 13.2 0.2 0.098 12.6 0.2 1.3 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain DUF4703 PF15775.5 KFX95005.1 - 0.39 10.5 2.8 0.59 9.9 2.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4703) Exo84_C PF16528.5 KFX95006.1 - 7.9e-75 251.2 1.1 7.9e-75 251.2 1.1 2.1 3 0 0 3 3 3 1 Exocyst component 84 C-terminal Vps51 PF08700.11 KFX95006.1 - 8.9e-16 57.7 2.8 8.9e-16 57.7 2.8 2.0 2 0 0 2 2 2 1 Vps51/Vps67 COG2 PF06148.11 KFX95006.1 - 0.023 14.8 0.3 0.023 14.8 0.3 2.5 3 0 0 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF4618 PF15397.6 KFX95006.1 - 0.098 12.1 3.1 0.17 11.3 1.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4618) DUF2383 PF09537.10 KFX95006.1 - 0.45 10.9 3.8 5.6 7.4 0.8 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF2383) DUF2130 PF09903.9 KFX95006.1 - 0.88 8.8 7.9 3.8 6.7 0.2 2.7 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2130) APG6_N PF17675.1 KFX95006.1 - 0.9 10.1 7.5 0.084 13.4 0.6 2.7 3 0 0 3 3 3 0 Apg6 coiled-coil region DUF4407 PF14362.6 KFX95006.1 - 4.1 6.7 7.0 0.75 9.1 0.8 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) DUF2443 PF10398.9 KFX95006.1 - 4.2 7.5 5.0 12 6.0 0.2 3.7 4 0 0 4 4 4 0 Protein of unknown function (DUF2443) Metallophos PF00149.28 KFX95007.1 - 4.9e-37 128.4 0.9 1.7e-36 126.6 0.6 2.0 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase Golgin_A5 PF09787.9 KFX95007.1 - 0.0028 17.2 2.1 0.0028 17.2 2.1 2.4 2 0 0 2 2 2 1 Golgin subfamily A member 5 Mt_ATP-synt_D PF05873.12 KFX95007.1 - 0.016 15.1 0.5 0.016 15.1 0.5 1.7 2 0 0 2 2 2 0 ATP synthase D chain, mitochondrial (ATP5H) Chlorosome_CsmC PF11098.8 KFX95007.1 - 0.2 11.6 0.0 0.37 10.8 0.0 1.3 1 0 0 1 1 1 0 Chlorosome envelope protein C XLF PF09302.11 KFX95007.1 - 0.22 11.7 0.1 0.22 11.7 0.1 2.1 2 0 0 2 2 2 0 XLF-Cernunnos, XRcc4-like factor, NHEJ component Hid1 PF12722.7 KFX95007.1 - 1.5 6.8 5.5 2.2 6.3 5.5 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein GREB1 PF15782.5 KFX95007.1 - 4.7 4.2 15.0 6.7 3.7 15.0 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer 4HBT_3 PF13622.6 KFX95008.1 - 2.5e-29 103.3 0.3 3e-29 103.0 0.3 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily Esterase_phd PF10503.9 KFX95009.1 - 5.8e-07 29.2 0.0 0.00021 20.9 0.0 2.4 2 0 0 2 2 2 2 Esterase PHB depolymerase Esterase PF00756.20 KFX95009.1 - 1.1e-05 25.2 0.0 1.7e-05 24.6 0.0 1.2 1 0 0 1 1 1 1 Putative esterase Peptidase_S9 PF00326.21 KFX95009.1 - 0.0051 16.3 0.1 0.014 14.8 0.1 1.7 1 1 1 2 2 2 1 Prolyl oligopeptidase family AXE1 PF05448.12 KFX95009.1 - 0.031 13.0 0.0 0.88 8.2 0.0 2.1 2 0 0 2 2 2 0 Acetyl xylan esterase (AXE1) Abhydrolase_2 PF02230.16 KFX95009.1 - 0.033 14.0 0.0 0.084 12.7 0.0 1.5 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase YlbD_coat PF14071.6 KFX95011.1 - 0.078 13.2 1.3 0.1 12.9 1.3 1.2 1 0 0 1 1 1 0 Putative coat protein CLN3 PF02487.17 KFX95011.1 - 0.088 11.8 0.0 0.11 11.5 0.0 1.0 1 0 0 1 1 1 0 CLN3 protein Whi5 PF08528.11 KFX95012.1 - 1.5e-08 34.1 0.0 2.3e-08 33.5 0.0 1.3 1 0 0 1 1 1 1 Whi5 like Asp PF00026.23 KFX95014.1 - 1.2e-63 215.5 5.9 1.4e-63 215.2 5.9 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KFX95014.1 - 2.2e-07 31.3 0.7 0.022 15.0 0.4 3.0 2 1 1 3 3 3 2 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 KFX95014.1 - 0.00034 21.2 4.2 0.048 14.3 2.1 3.4 2 1 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.6 KFX95014.1 - 0.23 12.0 5.1 1.3 9.6 0.4 3.4 3 1 0 3 3 3 0 gag-polyprotein putative aspartyl protease APH PF01636.23 KFX95015.1 - 1.5e-05 25.0 0.4 0.00016 21.7 0.4 2.1 1 1 0 1 1 1 1 Phosphotransferase enzyme family WSC PF01822.19 KFX95016.1 - 1.5e-36 124.4 30.2 1.2e-18 67.0 9.1 2.7 2 0 0 2 2 2 2 WSC domain peroxidase PF00141.23 KFX95016.1 - 1.7e-19 70.4 0.1 3.4e-19 69.5 0.1 1.4 1 0 0 1 1 1 1 Peroxidase Sporozoite_P67 PF05642.11 KFX95016.1 - 0.17 9.9 7.8 0.23 9.5 7.8 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen SET PF00856.28 KFX95017.1 - 3.5e-13 50.3 0.0 1.1e-12 48.7 0.0 1.8 1 1 0 1 1 1 1 SET domain DUF3632 PF12311.8 KFX95024.1 - 4.7e-28 98.8 0.0 6.2e-28 98.4 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3632) ABM PF03992.16 KFX95024.1 - 0.055 13.6 0.0 0.13 12.3 0.0 1.6 1 0 0 1 1 1 0 Antibiotic biosynthesis monooxygenase HET PF06985.11 KFX95025.1 - 1e-29 103.8 0.1 2.1e-29 102.8 0.1 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Yip1 PF04893.17 KFX95027.1 - 0.011 15.4 4.4 0.015 15.0 4.4 1.2 1 0 0 1 1 1 0 Yip1 domain NnrU PF07298.11 KFX95027.1 - 0.046 13.2 4.0 0.043 13.3 3.4 1.2 1 1 0 1 1 1 0 NnrU protein MAP17 PF15807.5 KFX95027.1 - 0.32 11.2 0.8 0.43 10.8 0.8 1.1 1 0 0 1 1 1 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 Peptidase_S10 PF00450.22 KFX95028.1 - 4.4e-83 280.0 1.1 7.5e-83 279.2 1.1 1.4 1 0 0 1 1 1 1 Serine carboxypeptidase Pkinase PF00069.25 KFX95028.1 - 1.3e-21 77.1 0.0 1.3e-20 73.9 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain Glycos_transf_1 PF00534.20 KFX95028.1 - 5.7e-17 61.8 0.0 1e-16 61.0 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 KFX95028.1 - 2.5e-11 44.1 0.0 4.6e-11 43.3 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Pkinase_Tyr PF07714.17 KFX95028.1 - 0.00022 20.6 0.0 0.14 11.4 0.0 2.5 2 0 0 2 2 2 2 Protein tyrosine kinase Glyco_trans_1_2 PF13524.6 KFX95028.1 - 0.0067 16.8 0.0 0.033 14.6 0.0 2.2 2 0 0 2 2 2 1 Glycosyl transferases group 1 TRAM_LAG1_CLN8 PF03798.16 KFX95029.1 - 5e-35 121.0 24.5 7.4e-35 120.5 24.5 1.3 1 0 0 1 1 1 1 TLC domain TRAM1 PF08390.11 KFX95029.1 - 1.7e-25 88.4 0.3 4.6e-25 87.0 0.0 1.9 2 0 0 2 2 2 1 TRAM1-like protein PET117 PF15786.5 KFX95029.1 - 0.076 13.3 0.2 0.16 12.2 0.2 1.5 1 0 0 1 1 1 0 PET assembly of cytochrome c oxidase, mitochondrial MDFI PF15316.6 KFX95029.1 - 1.2 9.3 2.2 1.8 8.6 2.2 1.2 1 0 0 1 1 1 0 MyoD family inhibitor TRAM_LAG1_CLN8 PF03798.16 KFX95030.1 - 5.3e-42 143.8 18.3 5.3e-42 143.8 18.3 1.9 2 0 0 2 2 2 1 TLC domain TRAM1 PF08390.11 KFX95030.1 - 2.2e-21 75.2 0.1 2.2e-21 75.2 0.1 2.5 2 0 0 2 2 2 1 TRAM1-like protein UQ_con PF00179.26 KFX95031.1 - 1.2e-42 144.9 0.0 1.3e-42 144.7 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 KFX95031.1 - 2.1e-06 27.4 0.0 2.9e-06 27.0 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 KFX95031.1 - 0.017 15.4 0.2 0.019 15.2 0.1 1.3 1 1 0 1 1 1 0 RWD domain UEV PF05743.13 KFX95031.1 - 0.12 12.3 0.1 0.15 11.9 0.1 1.2 1 0 0 1 1 1 0 UEV domain Peptidase_S24 PF00717.23 KFX95032.1 - 8.3e-08 32.1 0.0 1.2e-07 31.5 0.0 1.3 1 0 0 1 1 1 1 Peptidase S24-like Rhodanese_C PF12368.8 KFX95033.1 - 1.1e-10 41.7 8.8 3.2e-10 40.2 8.8 1.8 1 0 0 1 1 1 1 Rhodanase C-terminal UPF0176_N PF17773.1 KFX95033.1 - 2.9e-10 40.4 0.0 1.1e-09 38.5 0.0 2.0 2 0 0 2 2 2 1 UPF0176 acylphosphatase like domain Rhodanese PF00581.20 KFX95033.1 - 0.024 15.2 0.0 0.049 14.2 0.0 1.5 1 0 0 1 1 1 0 Rhodanese-like domain cEGF PF12662.7 KFX95033.1 - 0.41 10.6 5.6 0.094 12.7 1.2 2.3 2 0 0 2 2 2 0 Complement Clr-like EGF-like BTB PF00651.31 KFX95034.1 - 5e-08 33.2 0.0 1.3e-07 31.8 0.0 1.6 1 0 0 1 1 1 1 BTB/POZ domain Skp1_POZ PF03931.15 KFX95034.1 - 0.046 13.9 0.0 0.082 13.1 0.0 1.4 1 0 0 1 1 1 0 Skp1 family, tetramerisation domain Glyco_hydro_11 PF00457.17 KFX95035.1 - 3.9e-79 264.4 17.5 5.6e-79 263.9 17.5 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 11 CBM_1 PF00734.18 KFX95035.1 - 1.4e-10 40.9 16.0 5.7e-10 39.0 16.0 2.2 1 0 0 1 1 1 1 Fungal cellulose binding domain Toxin_7 PF05980.12 KFX95035.1 - 0.13 12.5 9.3 0.18 12.1 8.5 1.7 1 1 0 1 1 1 0 Toxin 7 CarboxypepD_reg PF13620.6 KFX95035.1 - 1.1 9.6 6.3 3.1 8.1 0.9 2.9 3 0 0 3 3 3 0 Carboxypeptidase regulatory-like domain Lipocalin_4 PF13648.6 KFX95035.1 - 3.8 8.5 16.1 1.2 10.2 8.4 3.0 1 1 2 3 3 3 0 Lipocalin-like domain UBD PF16455.5 KFX95036.1 - 1.1e-35 122.0 0.0 1.8e-35 121.3 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-binding domain ubiquitin PF00240.23 KFX95036.1 - 0.0034 17.1 0.0 0.0057 16.4 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 KFX95036.1 - 0.19 11.6 0.0 0.39 10.6 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like GFO_IDH_MocA PF01408.22 KFX95038.1 - 2.9e-18 66.8 0.0 5.7e-18 65.9 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 KFX95038.1 - 4.3e-17 62.2 0.1 3.8e-16 59.1 0.1 2.2 2 0 0 2 2 2 1 Oxidoreductase family, C-terminal alpha/beta domain NAD_binding_3 PF03447.16 KFX95038.1 - 0.021 15.5 0.0 0.032 14.9 0.0 1.3 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain Cys_Met_Meta_PP PF01053.20 KFX95038.1 - 0.1 11.1 0.0 0.17 10.4 0.0 1.2 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme Peptidase_S9 PF00326.21 KFX95040.1 - 1e-14 54.5 0.0 1.3e-14 54.2 0.0 1.1 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_3 PF07859.13 KFX95040.1 - 4.2e-07 30.0 0.0 4.7e-06 26.6 0.1 2.0 1 1 1 2 2 2 1 alpha/beta hydrolase fold DLH PF01738.18 KFX95040.1 - 7.1e-07 29.0 0.0 1.1e-06 28.4 0.0 1.2 1 0 0 1 1 1 1 Dienelactone hydrolase family Hydrolase_4 PF12146.8 KFX95040.1 - 5.3e-05 22.6 0.0 0.017 14.4 0.0 2.1 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KFX95040.1 - 0.0017 18.1 0.0 0.11 12.1 0.0 2.1 1 1 1 2 2 2 1 alpha/beta hydrolase fold FSH1 PF03959.13 KFX95040.1 - 0.0023 17.6 0.0 0.0028 17.4 0.0 1.2 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Peptidase_S15 PF02129.18 KFX95040.1 - 0.046 13.3 0.0 2.9 7.4 0.1 2.1 1 1 1 2 2 2 0 X-Pro dipeptidyl-peptidase (S15 family) DUF2048 PF09752.9 KFX95040.1 - 0.14 11.2 0.0 0.2 10.7 0.0 1.1 1 0 0 1 1 1 0 Abhydrolase domain containing 18 Sugar_tr PF00083.24 KFX95041.1 - 4.9e-76 256.4 29.0 5.8e-76 256.2 29.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KFX95041.1 - 3.4e-16 59.1 29.3 3.4e-16 59.1 29.3 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 KFX95041.1 - 0.04 12.8 18.2 0.011 14.6 7.5 2.3 2 0 0 2 2 2 0 MFS_1 like family DHquinase_I PF01487.15 KFX95043.1 - 1.8e-45 156.0 0.0 4.5e-45 154.7 0.0 1.6 2 0 0 2 2 2 1 Type I 3-dehydroquinase Sugar_tr PF00083.24 KFX95044.1 - 7.7e-129 430.5 36.0 8.8e-129 430.3 36.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KFX95044.1 - 7.6e-20 71.1 54.7 9e-17 61.0 24.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 KFX95044.1 - 0.0018 16.9 1.2 0.0018 16.9 1.2 2.7 3 1 0 3 3 3 1 MFS/sugar transport protein Glyco_hydro_43 PF04616.14 KFX95045.1 - 4.1e-60 203.5 0.5 9.7e-60 202.3 0.5 1.6 1 1 0 1 1 1 1 Glycosyl hydrolases family 43 GH43_C2 PF17851.1 KFX95045.1 - 4.5e-35 121.2 0.0 6e-35 120.8 0.0 1.2 1 0 0 1 1 1 1 Beta xylosidase C-terminal Concanavalin A-like domain Fungal_trans PF04082.18 KFX95046.1 - 1.7e-17 63.4 0.1 3.2e-17 62.5 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KFX95046.1 - 1e-08 35.2 10.2 1.8e-08 34.4 10.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Cellulase PF00150.18 KFX95048.1 - 3.2e-08 33.3 0.2 4.5e-07 29.6 0.2 2.0 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Nramp PF01566.18 KFX95049.1 - 4.1e-61 206.9 21.8 4.3e-60 203.6 21.8 2.1 1 1 0 1 1 1 1 Natural resistance-associated macrophage protein Med17 PF10156.9 KFX95050.1 - 3.4 6.3 8.5 4.4 5.9 8.5 1.1 1 0 0 1 1 1 0 Subunit 17 of Mediator complex Nop14 PF04147.12 KFX95050.1 - 8.9 4.4 17.6 10 4.1 17.6 1.0 1 0 0 1 1 1 0 Nop14-like family But2 PF09792.9 KFX95052.1 - 4.6e-60 202.1 2.3 7.3e-60 201.5 2.3 1.3 1 0 0 1 1 1 1 Ubiquitin 3 binding protein But2 C-terminal domain Peptidase_A4 PF01828.17 KFX95052.1 - 0.0045 16.5 0.7 0.0079 15.7 0.7 1.4 1 0 0 1 1 1 1 Peptidase A4 family CAP_N PF01213.19 KFX95052.1 - 0.31 10.5 1.6 0.43 10.0 1.6 1.1 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal tRNA-synt_1 PF00133.22 KFX95053.1 - 2.2e-218 726.4 0.1 3.6e-218 725.7 0.1 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 KFX95053.1 - 2.6e-26 92.4 0.0 6e-26 91.2 0.0 1.6 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 KFX95053.1 - 7.2e-16 57.9 0.0 1.3e-05 24.1 0.0 4.0 3 1 0 3 3 3 3 tRNA synthetases class I (M) Thioredoxin PF00085.20 KFX95054.1 - 2.2e-19 69.3 0.0 5.5e-19 68.1 0.0 1.6 2 0 0 2 2 2 1 Thioredoxin Acetyltransf_4 PF13420.7 KFX95054.1 - 3.3e-07 30.6 0.0 1.8 8.7 0.0 4.2 5 0 0 5 5 5 3 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KFX95054.1 - 0.00013 22.4 0.0 0.00088 19.6 0.0 2.2 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Thioredoxin_2 PF13098.6 KFX95054.1 - 0.00014 22.3 0.1 0.002 18.5 0.0 2.3 2 0 0 2 2 2 1 Thioredoxin-like domain Acetyltransf_1 PF00583.25 KFX95054.1 - 0.0011 19.2 0.0 0.0022 18.2 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KFX95054.1 - 0.0035 17.3 0.0 0.022 14.7 0.0 2.2 3 0 0 3 3 3 1 Acetyltransferase (GNAT) domain Thioredoxin_8 PF13905.6 KFX95054.1 - 0.013 15.8 0.0 0.079 13.3 0.0 2.2 2 1 1 3 3 3 0 Thioredoxin-like OST3_OST6 PF04756.13 KFX95054.1 - 0.023 14.1 0.0 0.031 13.6 0.0 1.3 1 0 0 1 1 1 0 OST3 / OST6 family, transporter family AhpC-TSA PF00578.21 KFX95054.1 - 0.12 12.3 0.0 0.36 10.8 0.0 1.9 2 0 0 2 2 2 0 AhpC/TSA family Redoxin PF08534.10 KFX95054.1 - 0.16 11.7 0.0 0.61 9.8 0.0 2.0 2 1 0 2 2 2 0 Redoxin Abhydrolase_3 PF07859.13 KFX95055.1 - 3.6e-30 105.4 0.0 4.6e-30 105.1 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold DLH PF01738.18 KFX95055.1 - 8.6e-09 35.3 0.0 0.0031 17.1 0.1 2.1 2 0 0 2 2 2 2 Dienelactone hydrolase family COesterase PF00135.28 KFX95055.1 - 0.0019 17.1 0.0 0.0032 16.4 0.0 1.3 1 0 0 1 1 1 1 Carboxylesterase family BAAT_C PF08840.11 KFX95055.1 - 0.0075 16.2 0.0 0.012 15.5 0.0 1.3 1 1 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal Esterase PF00756.20 KFX95055.1 - 0.015 15.0 0.0 4.6 6.8 0.0 2.2 2 0 0 2 2 2 0 Putative esterase DUF2974 PF11187.8 KFX95055.1 - 0.048 13.2 0.0 0.095 12.2 0.0 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF2974) Troponin-I_N PF11636.8 KFX95055.1 - 3.8 7.5 9.3 45 4.1 0.0 3.6 3 0 0 3 3 3 0 Troponin I residues 1-32 Phytase PF02333.15 KFX95057.1 - 9.8e-62 209.1 4.7 6.6e-60 203.0 0.1 2.3 2 0 0 2 2 2 2 Phytase EGF_2 PF07974.13 KFX95057.1 - 1.1e-06 28.8 31.3 0.0037 17.6 14.3 2.5 2 0 0 2 2 2 2 EGF-like domain EGF PF00008.27 KFX95057.1 - 0.0029 17.9 5.4 0.0029 17.9 5.4 2.5 2 0 0 2 2 2 2 EGF-like domain hEGF PF12661.7 KFX95057.1 - 0.034 14.8 16.5 0.057 14.1 5.7 2.8 2 0 0 2 2 2 0 Human growth factor-like EGF adh_short PF00106.25 KFX95058.1 - 1.3e-30 106.3 0.0 1.6e-30 106.1 0.0 1.0 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KFX95058.1 - 2.1e-16 60.2 0.0 2.7e-16 59.8 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KFX95058.1 - 1.1e-08 35.2 0.0 1.5e-08 34.8 0.0 1.1 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 KFX95058.1 - 4.8e-06 25.9 0.0 5.6e-06 25.7 0.0 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Epimerase PF01370.21 KFX95058.1 - 0.00021 20.8 0.0 0.001 18.6 0.0 1.8 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KFX95058.1 - 0.0024 17.3 0.0 0.0069 15.8 0.0 1.6 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase Glyco_tran_WecB PF03808.13 KFX95058.1 - 0.05 13.5 0.0 0.27 11.2 0.0 1.9 2 0 0 2 2 2 0 Glycosyl transferase WecB/TagA/CpsF family LDcluster4 PF18306.1 KFX95058.1 - 0.06 12.9 0.1 0.089 12.4 0.1 1.2 1 0 0 1 1 1 0 SLOG cluster4 family Ank_2 PF12796.7 KFX95059.1 - 1.2e-39 134.7 0.2 2.7e-13 50.3 0.0 5.3 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KFX95059.1 - 3.4e-29 97.7 6.3 0.00033 20.9 0.0 7.8 7 0 0 7 7 7 7 Ankyrin repeat Ank_5 PF13857.6 KFX95059.1 - 4.8e-28 96.9 9.0 4.3e-06 26.9 0.0 6.9 4 1 3 7 7 7 6 Ankyrin repeats (many copies) Ank_4 PF13637.6 KFX95059.1 - 6.6e-28 96.7 1.8 6.3e-07 29.8 0.0 6.1 3 2 4 7 7 7 7 Ankyrin repeats (many copies) Ank PF00023.30 KFX95059.1 - 2.9e-24 84.4 6.6 0.00033 21.0 0.0 7.9 8 0 0 8 8 8 6 Ankyrin repeat Glyco_hydro_26 PF02156.15 KFX95060.1 - 5.9e-74 249.3 2.9 6.9e-74 249.1 2.9 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 26 Melibiase_2 PF16499.5 KFX95061.1 - 4.5e-56 190.1 5.0 5.1e-40 137.4 1.3 2.3 2 0 0 2 2 2 2 Alpha galactosidase A Melibiase_C PF17801.1 KFX95061.1 - 2.5e-09 37.1 2.2 1.6e-08 34.5 0.0 2.9 4 0 0 4 4 4 1 Alpha galactosidase C-terminal beta sandwich domain Melibiase PF02065.18 KFX95061.1 - 9.5e-08 31.4 0.0 1.8e-07 30.4 0.0 1.4 1 0 0 1 1 1 1 Melibiase Raffinose_syn PF05691.12 KFX95061.1 - 0.017 12.9 0.2 0.023 12.5 0.2 1.1 1 0 0 1 1 1 0 Raffinose synthase or seed imbibition protein Sip1 Glyco_hydro_7 PF00840.20 KFX95062.1 - 3.2e-125 418.3 6.7 4e-125 417.9 6.7 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 7 FGGY_C PF02782.16 KFX95063.1 - 2.8e-69 232.8 2.5 4.9e-69 232.0 2.5 1.4 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.21 KFX95063.1 - 2.1e-65 220.7 0.0 3.2e-65 220.1 0.0 1.3 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain Aminotran_4 PF01063.19 KFX95064.1 - 5.9e-28 98.2 0.0 7.5e-28 97.9 0.0 1.1 1 0 0 1 1 1 1 Amino-transferase class IV Cucumopine_C PF18631.1 KFX95065.1 - 8.3e-52 174.9 0.0 1.2e-51 174.4 0.0 1.2 1 0 0 1 1 1 1 Cucumopine synthase C-terminal helical bundle domain DUF3830 PF12903.7 KFX95065.1 - 0.0025 17.5 0.1 0.06 13.0 0.1 2.2 1 1 0 1 1 1 1 Protein of unknown function (DUF3830) p450 PF00067.22 KFX95066.1 - 2.1e-51 175.1 0.0 2.8e-51 174.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Glyoxalase PF00903.25 KFX95066.1 - 6.9e-10 39.2 0.0 1.4e-09 38.2 0.0 1.5 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_3 PF13468.6 KFX95066.1 - 0.00093 19.4 0.0 0.84 9.7 0.0 2.5 2 0 0 2 2 2 2 Glyoxalase-like domain Glyoxalase_4 PF13669.6 KFX95066.1 - 0.002 18.4 0.0 0.0086 16.3 0.0 2.1 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily AMP-binding PF00501.28 KFX95068.1 - 6.6e-48 163.4 0.0 8.9e-48 162.9 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KFX95068.1 - 2e-09 38.3 0.0 3.8e-09 37.4 0.0 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain AA_permease_2 PF13520.6 KFX95069.1 - 1.2e-47 162.7 51.9 1.5e-47 162.4 51.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KFX95069.1 - 1.8e-26 92.8 45.6 2.9e-26 92.1 45.6 1.2 1 0 0 1 1 1 1 Amino acid permease Aminotran_1_2 PF00155.21 KFX95070.1 - 3.6e-23 82.3 0.0 4.6e-23 82.0 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.7 KFX95070.1 - 0.00059 18.7 0.0 0.0015 17.4 0.0 1.7 1 1 0 1 1 1 1 Alanine-glyoxylate amino-transferase RNase_Zc3h12a PF11977.8 KFX95070.1 - 0.17 11.7 0.1 0.32 10.7 0.1 1.4 1 0 0 1 1 1 0 Zc3h12a-like Ribonuclease NYN domain Fungal_trans_2 PF11951.8 KFX95071.1 - 2.7e-53 181.2 2.9 2.7e-53 181.2 2.9 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain PolyA_pol PF01743.20 KFX95071.1 - 7.6e-22 78.1 0.2 7.5e-21 74.9 0.2 2.4 1 1 0 1 1 1 1 Poly A polymerase head domain PolyA_pol_RNAbd PF12627.7 KFX95071.1 - 1.5e-06 27.9 0.4 3.7e-06 26.6 0.0 1.8 2 0 0 2 2 2 1 Probable RNA and SrmB- binding site of polymerase A MOR2-PAG1_N PF14222.6 KFX95071.1 - 0.094 11.6 0.0 0.14 11.1 0.0 1.2 1 0 0 1 1 1 0 Cell morphogenesis N-terminal DUF3611 PF12263.8 KFX95072.1 - 0.041 13.8 0.0 0.061 13.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3611) TMEM223 PF14640.6 KFX95072.1 - 0.089 13.0 0.0 0.14 12.3 0.0 1.2 1 0 0 1 1 1 0 Transmembrane protein 223 FeoB_associated PF12669.7 KFX95072.1 - 0.13 12.7 0.3 0.13 12.7 0.3 2.0 2 0 0 2 2 2 0 FeoB-associated Cys-rich membrane protein COesterase PF00135.28 KFX95078.1 - 2.9e-79 267.3 0.0 4e-79 266.8 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family DUF1264 PF06884.11 KFX95078.1 - 6.8e-77 256.9 0.0 9.6e-77 256.4 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1264) Abhydrolase_3 PF07859.13 KFX95078.1 - 0.015 15.2 0.0 0.037 13.9 0.0 1.6 1 0 0 1 1 1 0 alpha/beta hydrolase fold ABC_membrane PF00664.23 KFX95079.1 - 5.5e-86 288.6 25.5 7.2e-46 157.0 6.6 2.4 2 1 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 KFX95079.1 - 5.3e-65 218.1 0.1 3.1e-32 111.9 0.2 2.4 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 KFX95079.1 - 1.5e-14 54.0 0.0 4.3e-05 23.1 0.0 4.1 2 2 2 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 KFX95079.1 - 2.4e-06 27.8 1.6 0.4 10.9 0.1 4.4 4 1 0 4 4 3 2 AAA domain AAA_29 PF13555.6 KFX95079.1 - 8.3e-06 25.5 0.2 0.21 11.4 0.1 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.6 KFX95079.1 - 9.6e-06 26.1 1.5 0.052 13.9 0.3 3.2 2 2 0 2 2 2 2 AAA ATPase domain AAA_21 PF13304.6 KFX95079.1 - 1.8e-05 24.7 3.5 1 9.1 0.2 4.1 3 1 1 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 KFX95079.1 - 5.9e-05 23.0 0.1 0.45 10.4 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase SbcCD_C PF13558.6 KFX95079.1 - 0.00012 22.2 1.0 0.38 11.0 0.2 4.0 3 1 0 3 3 3 1 Putative exonuclease SbcCD, C subunit AAA_30 PF13604.6 KFX95079.1 - 0.00038 20.2 2.1 2.8 7.6 0.0 4.3 4 0 0 4 4 4 1 AAA domain AAA_18 PF13238.6 KFX95079.1 - 0.0005 20.6 0.0 0.99 10.0 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_5 PF07728.14 KFX95079.1 - 0.00093 19.2 0.1 0.45 10.5 0.0 2.8 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) Zeta_toxin PF06414.12 KFX95079.1 - 0.0013 18.0 0.0 0.1 11.9 0.0 2.4 2 0 0 2 2 2 1 Zeta toxin AAA_25 PF13481.6 KFX95079.1 - 0.0015 18.2 0.1 5.1 6.6 0.0 3.4 4 0 0 4 4 4 2 AAA domain AAA_33 PF13671.6 KFX95079.1 - 0.0042 17.3 0.2 1.4 9.1 0.0 2.6 2 0 0 2 2 2 1 AAA domain APS_kinase PF01583.20 KFX95079.1 - 0.0052 16.7 0.2 3 7.7 0.1 2.5 2 0 0 2 2 2 1 Adenylylsulphate kinase ECH_2 PF16113.5 KFX95079.1 - 0.025 14.1 0.0 0.048 13.2 0.0 1.4 1 0 0 1 1 1 0 Enoyl-CoA hydratase/isomerase ABC_ATPase PF09818.9 KFX95079.1 - 0.041 12.7 0.2 4.6 5.9 0.0 2.4 2 0 0 2 2 2 0 Predicted ATPase of the ABC class AAA PF00004.29 KFX95079.1 - 0.069 13.6 0.7 40 4.6 0.1 3.7 3 1 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.6 KFX95079.1 - 0.08 13.4 0.1 31 5.0 0.0 3.2 2 1 1 3 3 3 0 AAA domain Gtr1_RagA PF04670.12 KFX95079.1 - 0.16 11.3 0.1 11 5.3 0.0 2.4 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region AAA_7 PF12775.7 KFX95079.1 - 0.16 11.4 0.1 16 4.9 0.0 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region Rad17 PF03215.15 KFX95079.1 - 0.21 11.5 0.0 4.4 7.2 0.0 2.3 2 0 0 2 2 2 0 Rad17 P-loop domain MMR_HSR1 PF01926.23 KFX95079.1 - 0.22 11.6 0.4 31 4.7 0.1 2.8 2 0 0 2 2 2 0 50S ribosome-binding GTPase Cad PF03596.13 KFX95079.1 - 0.23 11.3 5.5 0.089 12.7 0.7 2.4 2 0 0 2 2 2 0 Cadmium resistance transporter Acetyltransf_3 PF13302.7 KFX95080.1 - 1.2e-20 74.5 0.0 9.7e-20 71.7 0.0 1.9 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KFX95080.1 - 0.045 14.0 0.0 0.064 13.5 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family MFS_1 PF07690.16 KFX95081.1 - 9.8e-11 41.2 59.7 3.5e-10 39.3 52.1 3.1 2 1 0 2 2 2 1 Major Facilitator Superfamily DUF4235 PF14019.6 KFX95081.1 - 1.9 8.6 5.4 2.1 8.5 1.8 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF4235) Esterase PF00756.20 KFX95082.1 - 5.9e-16 58.9 0.1 7.7e-16 58.5 0.1 1.2 1 0 0 1 1 1 1 Putative esterase Peptidase_S9 PF00326.21 KFX95082.1 - 1.2e-05 24.9 0.0 2e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 KFX95082.1 - 0.00059 19.2 0.0 0.00082 18.7 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KFX95082.1 - 0.043 14.4 0.2 0.063 13.9 0.1 1.4 1 1 0 1 1 1 0 Alpha/beta hydrolase family UPF0220 PF05255.11 KFX95083.1 - 2.1e-44 151.0 1.7 2.3e-44 150.9 1.7 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0220) PQQ_3 PF13570.6 KFX95083.1 - 0.044 14.3 0.0 0.11 13.1 0.0 1.7 1 0 0 1 1 1 0 PQQ-like domain RhodobacterPufX PF11511.8 KFX95083.1 - 0.09 12.4 1.9 0.45 10.2 0.1 2.1 2 0 0 2 2 2 0 Intrinsic membrane protein PufX SMI1_KNR4 PF09346.10 KFX95084.1 - 5.3e-34 117.5 0.0 1e-33 116.5 0.0 1.5 1 0 0 1 1 1 1 SMI1 / KNR4 family (SUKH-1) Tctex-1 PF03645.13 KFX95095.1 - 1.2e-20 73.6 0.0 1.6e-20 73.2 0.0 1.2 1 0 0 1 1 1 1 Tctex-1 family TPR_12 PF13424.6 KFX95096.1 - 4e-50 168.0 16.5 3.7e-11 43.1 0.7 7.5 4 2 4 8 8 8 7 Tetratricopeptide repeat TPR_10 PF13374.6 KFX95096.1 - 2.1e-48 160.9 4.7 9e-08 31.7 0.0 9.9 10 0 0 10 10 10 9 Tetratricopeptide repeat TPR_MalT PF17874.1 KFX95096.1 - 1.5e-09 37.7 2.7 3.2e-06 26.7 0.2 3.1 3 0 0 3 3 3 2 MalT-like TPR region TPR_7 PF13176.6 KFX95096.1 - 3.1e-06 26.8 13.0 0.35 11.0 0.0 6.8 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_17 PF13431.6 KFX95096.1 - 2.8e-05 24.2 0.4 6.8 7.3 0.0 5.6 6 0 0 6 6 5 1 Tetratricopeptide repeat TPR_2 PF07719.17 KFX95096.1 - 4e-05 23.4 14.9 1.4 9.2 0.2 6.9 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_4 PF07721.14 KFX95096.1 - 0.00018 21.8 0.4 2.5 9.0 0.0 5.0 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_19 PF14559.6 KFX95096.1 - 0.1 13.1 3.9 1.5 9.4 0.0 3.8 3 1 1 4 4 4 0 Tetratricopeptide repeat ANAPC3 PF12895.7 KFX95096.1 - 0.1 12.8 6.1 14 6.0 0.1 4.5 3 1 1 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_1 PF00515.28 KFX95096.1 - 0.11 12.3 18.0 9.4 6.2 0.0 7.5 9 0 0 9 9 9 0 Tetratricopeptide repeat TPR_14 PF13428.6 KFX95096.1 - 0.25 12.3 9.6 6 8.0 0.1 5.9 6 1 1 7 7 6 0 Tetratricopeptide repeat TPR_16 PF13432.6 KFX95096.1 - 0.25 12.0 13.7 12 6.6 0.1 5.7 5 2 0 6 6 6 0 Tetratricopeptide repeat TPR_6 PF13174.6 KFX95096.1 - 3.8 8.4 8.0 77 4.3 0.0 5.2 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_8 PF13181.6 KFX95096.1 - 9.5 6.7 15.8 11 6.5 0.0 6.6 9 0 0 9 9 9 0 Tetratricopeptide repeat Gal_GalNac_35kD PF17337.2 KFX95099.1 - 0.065 13.3 0.0 0.094 12.7 0.0 1.2 1 0 0 1 1 1 0 Galactose-inhibitable lectin 35 kDa subunit Peptidase_S28 PF05577.12 KFX95100.1 - 7.4e-48 163.4 0.0 3.8e-47 161.1 0.0 1.8 1 1 0 1 1 1 1 Serine carboxypeptidase S28 Peptidase_S37 PF05576.11 KFX95100.1 - 0.00018 20.3 0.3 0.29 9.7 0.1 2.2 2 0 0 2 2 2 2 PS-10 peptidase S37 CorA PF01544.18 KFX95105.1 - 3.1e-40 138.3 0.1 6.6e-40 137.3 0.1 1.4 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein TBCA PF02970.16 KFX95106.1 - 2.5e-25 88.6 12.6 2.5e-25 88.6 12.6 1.5 1 1 0 1 1 1 1 Tubulin binding cofactor A YkyA PF10368.9 KFX95106.1 - 0.0097 15.6 12.8 0.0097 15.6 12.8 2.1 1 1 1 2 2 2 1 Putative cell-wall binding lipoprotein MHCassoc_trimer PF08831.10 KFX95106.1 - 0.011 15.7 0.1 0.022 14.8 0.0 1.5 1 1 0 1 1 1 0 Class II MHC-associated invariant chain trimerisation domain Dynamin_M PF01031.20 KFX95106.1 - 0.039 13.2 0.3 0.039 13.2 0.3 2.0 1 1 1 2 2 2 0 Dynamin central region DUF4239 PF14023.6 KFX95106.1 - 0.04 13.7 3.9 0.046 13.4 3.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4239) D123 PF07065.14 KFX95106.1 - 0.044 12.9 2.3 0.05 12.7 2.3 1.1 1 0 0 1 1 1 0 D123 DUF2408 PF10303.9 KFX95106.1 - 0.083 13.5 4.6 0.1 13.2 4.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2408) SNARE PF05739.19 KFX95106.1 - 0.1 12.6 1.3 7.6 6.6 0.1 2.5 2 0 0 2 2 2 0 SNARE domain Spc7 PF08317.11 KFX95106.1 - 0.14 11.0 15.1 0.17 10.7 15.1 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein YlbE PF14003.6 KFX95106.1 - 0.33 11.4 3.1 1.9 9.0 1.1 2.2 1 1 1 2 2 2 0 YlbE-like protein FapA PF03961.13 KFX95106.1 - 0.38 9.3 9.5 0.45 9.1 9.5 1.0 1 0 0 1 1 1 0 Flagellar Assembly Protein A V_ATPase_I PF01496.19 KFX95106.1 - 0.43 8.4 8.8 0.49 8.3 8.8 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family HSP70 PF00012.20 KFX95106.1 - 1.2 7.3 11.2 1.3 7.1 11.2 1.0 1 0 0 1 1 1 0 Hsp70 protein TFR_dimer PF04253.15 KFX95106.1 - 1.3 9.2 5.4 0.73 9.9 1.0 2.2 1 1 1 2 2 2 0 Transferrin receptor-like dimerisation domain Uso1_p115_C PF04871.13 KFX95106.1 - 1.3 9.4 19.8 0.16 12.3 6.2 2.0 1 1 1 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region DUF883 PF05957.13 KFX95106.1 - 1.5 9.4 8.2 11 6.8 8.2 2.3 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF883) DcpS_C PF11969.8 KFX95109.1 - 6.1e-30 104.0 0.1 1.2e-29 103.1 0.1 1.5 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding DcpS PF05652.12 KFX95109.1 - 2.3e-26 92.6 0.0 3.7e-26 92.0 0.0 1.3 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme (DcpS) N-terminal Myb_Cef PF11831.8 KFX95111.1 - 6.4e-49 166.7 3.0 6.4e-49 166.7 3.0 2.8 3 0 0 3 3 3 1 pre-mRNA splicing factor component Myb_DNA-binding PF00249.31 KFX95111.1 - 3.5e-21 75.1 5.6 9.6e-10 38.5 0.8 2.9 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KFX95111.1 - 9e-19 67.5 5.2 2.8e-13 49.9 1.3 2.9 1 1 1 2 2 2 2 Myb-like DNA-binding domain Rap1_C PF11626.8 KFX95111.1 - 0.046 13.8 4.1 0.082 13.0 0.0 3.0 3 0 0 3 3 3 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain BAG PF02179.16 KFX95111.1 - 0.5 10.8 5.2 0.84 10.1 2.9 2.7 2 0 0 2 2 2 0 BAG domain Aldedh PF00171.22 KFX95112.1 - 1e-139 466.1 0.0 1.2e-139 465.8 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.14 KFX95112.1 - 0.0021 17.2 0.0 0.0034 16.5 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA reductase (LuxC) Glyco_trans_2_3 PF13632.6 KFX95120.1 - 2.9e-19 69.8 1.3 8.8e-19 68.2 1.3 1.8 1 1 0 1 1 1 1 Glycosyl transferase family group 2 SpoIIIAH PF12685.7 KFX95124.1 - 6.6 6.5 19.0 12 5.6 19.0 1.3 1 0 0 1 1 1 0 SpoIIIAH-like protein ABC2_membrane PF01061.24 KFX95131.1 - 1.1e-80 270.0 60.7 3.1e-41 141.1 26.6 3.2 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.27 KFX95131.1 - 1.2e-32 113.3 0.0 1e-16 61.7 0.0 2.6 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.12 KFX95131.1 - 3.2e-32 110.3 9.2 1.6e-29 101.6 0.1 3.8 3 0 0 3 3 3 2 CDR ABC transporter ABC_trans_N PF14510.6 KFX95131.1 - 2.1e-13 50.7 0.1 6.7e-13 49.1 0.1 1.9 1 0 0 1 1 1 1 ABC-transporter N-terminal ABC2_membrane_3 PF12698.7 KFX95131.1 - 5.1e-09 35.7 30.9 0.00018 20.7 16.6 2.4 2 0 0 2 2 2 2 ABC-2 family transporter protein AAA_18 PF13238.6 KFX95131.1 - 2.6e-06 28.0 0.0 0.0019 18.8 0.0 2.6 2 0 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 KFX95131.1 - 2.9e-06 27.3 0.5 0.00013 22.0 0.1 2.3 2 0 0 2 2 2 1 RsgA GTPase AAA_21 PF13304.6 KFX95131.1 - 2.3e-05 24.4 0.0 0.37 10.6 0.0 3.3 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 KFX95131.1 - 4.5e-05 23.9 0.2 0.041 14.3 0.0 2.6 2 0 0 2 2 2 2 AAA ATPase domain AAA_25 PF13481.6 KFX95131.1 - 0.0001 21.9 0.1 0.00059 19.5 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 KFX95131.1 - 0.00012 22.3 0.0 0.014 15.5 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 KFX95131.1 - 0.00054 19.7 0.9 0.052 13.3 0.3 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_28 PF13521.6 KFX95131.1 - 0.00086 19.6 0.2 1 9.6 0.0 2.6 2 0 0 2 2 2 2 AAA domain SMC_N PF02463.19 KFX95131.1 - 0.0058 16.1 0.0 0.99 8.8 0.0 3.4 3 1 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_17 PF13207.6 KFX95131.1 - 0.018 15.5 3.7 1.7 9.1 0.0 3.3 3 0 0 3 3 3 0 AAA domain AAA PF00004.29 KFX95131.1 - 0.018 15.4 0.1 6.4 7.2 0.0 2.7 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) NACHT PF05729.12 KFX95131.1 - 0.027 14.4 1.3 4.1 7.3 0.3 2.7 2 0 0 2 2 2 0 NACHT domain cobW PF02492.19 KFX95131.1 - 0.035 13.7 1.3 1.3 8.5 0.2 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_22 PF13401.6 KFX95131.1 - 0.043 14.1 2.5 2.8 8.2 0.2 3.5 4 0 0 4 4 3 0 AAA domain AAA_30 PF13604.6 KFX95131.1 - 0.044 13.5 0.0 1.2 8.8 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 KFX95131.1 - 0.064 13.0 1.0 19 4.9 0.1 3.3 3 0 0 3 3 3 0 AAA domain dNK PF01712.19 KFX95131.1 - 0.065 13.1 0.0 7.6 6.3 0.0 2.4 2 0 0 2 2 2 0 Deoxynucleoside kinase AAA_5 PF07728.14 KFX95131.1 - 0.11 12.4 0.1 12 5.9 0.0 2.7 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) DUF3671 PF12420.8 KFX95131.1 - 3.2 7.8 5.1 17 5.6 0.3 3.5 3 1 0 3 3 3 0 Protein of unknown function Zn_clus PF00172.18 KFX95132.1 - 8.1e-07 29.1 13.0 8.1e-07 29.1 13.0 1.8 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Prot_inhib_II PF02428.15 KFX95132.1 - 1.2 9.6 7.8 2.5 8.6 7.8 1.5 1 0 0 1 1 1 0 Potato type II proteinase inhibitor family Glyco_hydro_67M PF07488.12 KFX95142.1 - 4.2e-146 486.2 0.1 7.2e-146 485.4 0.1 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 67 middle domain Glyco_hydro_67C PF07477.12 KFX95142.1 - 4.7e-89 297.7 4.3 6.8e-89 297.2 4.3 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 67 C-terminus Glyco_hydro_67N PF03648.14 KFX95142.1 - 6.4e-30 103.9 0.0 1.1e-29 103.2 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 67 N-terminus Glyco_hydro_20b PF02838.15 KFX95142.1 - 0.0013 19.5 0.0 0.0036 18.1 0.0 1.7 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, domain 2 Pkinase PF00069.25 KFX95143.1 - 1.7e-64 217.7 0.0 2.4e-64 217.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFX95143.1 - 1.8e-29 102.8 0.0 3.9e-29 101.7 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 KFX95143.1 - 0.037 13.0 0.1 0.051 12.5 0.1 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Kinase-like PF14531.6 KFX95143.1 - 0.17 11.2 0.0 0.3 10.3 0.0 1.5 1 1 0 1 1 1 0 Kinase-like APH PF01636.23 KFX95143.1 - 0.18 11.7 0.0 0.37 10.7 0.0 1.4 1 1 0 1 1 1 0 Phosphotransferase enzyme family Sugar_tr PF00083.24 KFX95144.1 - 2.4e-83 280.5 25.2 9.5e-82 275.2 25.2 2.0 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KFX95144.1 - 2e-30 105.9 42.6 4.7e-29 101.4 35.1 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 KFX95144.1 - 0.00082 18.8 9.3 0.00082 18.8 9.3 3.0 2 1 1 3 3 3 1 Uncharacterised MFS-type transporter YbfB Actin PF00022.19 KFX95145.1 - 1.2e-111 373.2 0.0 5.4e-111 371.1 0.0 1.7 1 1 0 1 1 1 1 Actin MreB_Mbl PF06723.13 KFX95145.1 - 0.0044 15.9 0.0 0.015 14.1 0.0 1.9 1 1 0 1 1 1 1 MreB/Mbl protein Hexapep PF00132.24 KFX95147.1 - 5.2e-08 32.3 8.8 0.00026 20.6 1.8 4.5 3 1 1 4 4 4 3 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 KFX95147.1 - 5.4e-05 22.9 11.1 0.00024 20.8 0.4 4.0 3 1 1 4 4 4 2 Hexapeptide repeat of succinyl-transferase Fucokinase PF07959.12 KFX95147.1 - 0.034 13.1 0.0 0.052 12.5 0.0 1.2 1 0 0 1 1 1 0 L-fucokinase PMI_typeI PF01238.21 KFX95148.1 - 4e-141 470.5 0.0 4.7e-141 470.3 0.0 1.0 1 0 0 1 1 1 1 Phosphomannose isomerase type I FAD_binding_3 PF01494.19 KFX95149.1 - 2.9e-18 66.3 0.0 8.7e-18 64.7 0.0 1.7 1 1 0 1 1 1 1 FAD binding domain Amino_oxidase PF01593.24 KFX95149.1 - 1.1e-05 24.9 0.3 0.0035 16.7 0.2 2.2 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase Pyr_redox_2 PF07992.14 KFX95149.1 - 0.00055 19.2 0.2 0.075 12.2 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KFX95149.1 - 0.0027 17.0 0.0 0.079 12.2 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KFX95149.1 - 0.048 13.9 0.1 0.11 12.7 0.1 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 KFX95149.1 - 0.069 12.2 0.2 0.41 9.7 0.2 2.0 1 1 0 1 1 1 0 Lycopene cyclase protein Pyr_redox PF00070.27 KFX95149.1 - 0.79 10.3 2.9 14 6.3 0.1 3.1 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase RTA1 PF04479.13 KFX95151.1 - 1.5e-70 237.0 2.1 2.3e-70 236.4 2.1 1.2 1 0 0 1 1 1 1 RTA1 like protein Class_IIIsignal PF04021.12 KFX95151.1 - 1.6 8.8 4.5 0.58 10.2 0.8 2.4 2 0 0 2 2 2 0 Class III signal peptide PhyH PF05721.13 KFX95152.1 - 0.00012 22.4 0.1 0.00032 21.0 0.1 1.7 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) DUF4191 PF13829.6 KFX95156.1 - 0.17 11.2 0.6 0.19 11.1 0.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4191) LapA_dom PF06305.11 KFX95156.1 - 1.3 8.9 4.7 1.9 8.3 4.7 1.3 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain Ndc1_Nup PF09531.10 KFX95157.1 - 0.021 13.6 0.6 0.25 10.0 0.1 2.3 2 0 0 2 2 2 0 Nucleoporin protein Ndc1-Nup ABC_membrane_3 PF13748.6 KFX95157.1 - 0.022 14.0 0.7 0.043 13.1 0.7 1.4 1 0 0 1 1 1 0 ABC transporter transmembrane region Defensin_big PF14862.6 KFX95157.1 - 0.13 12.5 3.9 1.6 9.1 0.0 3.3 3 0 0 3 3 3 0 Big defensin zf-3CxxC PF13695.6 KFX95163.1 - 1e-19 70.8 0.6 2e-19 69.9 0.6 1.5 1 0 0 1 1 1 1 Zinc-binding domain F-box-like PF12937.7 KFX95163.1 - 6.4e-07 29.2 0.1 1.7e-06 27.8 0.2 1.7 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 KFX95163.1 - 0.00066 19.5 0.1 0.0021 17.9 0.1 1.8 1 0 0 1 1 1 1 F-box domain Rad52_Rad22 PF04098.15 KFX95163.1 - 0.048 13.6 0.0 0.095 12.6 0.0 1.4 1 0 0 1 1 1 0 Rad52/22 family double-strand break repair protein zf-3CxxC_2 PF17180.4 KFX95163.1 - 0.66 10.8 3.8 18 6.2 3.8 2.7 1 1 0 1 1 1 0 Zinc-binding domain Ank_2 PF12796.7 KFX95164.1 - 3.3e-17 62.8 0.2 5.7e-08 33.2 0.0 3.6 1 1 2 3 3 3 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KFX95164.1 - 1.3e-16 59.0 2.5 0.00018 21.7 0.1 6.7 6 1 0 6 6 6 4 Ankyrin repeat Ank_4 PF13637.6 KFX95164.1 - 3e-15 56.3 2.0 3.2e-06 27.6 0.1 4.4 2 2 2 4 4 4 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 KFX95164.1 - 2.3e-14 53.2 1.7 2.3e-06 27.7 0.1 3.6 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 KFX95164.1 - 1.8e-13 50.3 4.3 3.7e-05 24.0 0.9 4.5 4 0 0 4 4 4 2 Ankyrin repeat F-box-like PF12937.7 KFX95164.1 - 4e-05 23.4 0.0 8.4e-05 22.4 0.0 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KFX95164.1 - 0.032 14.1 0.1 0.068 13.1 0.1 1.5 1 0 0 1 1 1 0 F-box domain Beta-lactamase PF00144.24 KFX95165.1 - 5e-34 118.0 0.0 7e-34 117.5 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase Acetyltransf_10 PF13673.7 KFX95165.1 - 0.00099 19.1 0.3 0.0019 18.2 0.3 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KFX95165.1 - 0.035 14.3 0.0 0.16 12.2 0.0 2.1 2 0 0 2 2 2 0 Acetyltransferase (GNAT) family DUF1748 PF08520.10 KFX95169.1 - 5.3e-34 115.9 0.1 6.3e-34 115.7 0.1 1.1 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1748) PK PF00224.21 KFX95170.1 - 3e-169 562.4 6.3 4.9e-169 561.7 6.3 1.3 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain PK_C PF02887.16 KFX95170.1 - 1.9e-33 115.2 0.0 1.3e-32 112.5 0.0 2.4 3 0 0 3 3 3 1 Pyruvate kinase, alpha/beta domain HpcH_HpaI PF03328.14 KFX95170.1 - 0.0006 19.0 2.2 0.0037 16.4 0.4 2.3 1 1 1 2 2 2 1 HpcH/HpaI aldolase/citrate lyase family IMPDH PF00478.25 KFX95170.1 - 0.021 13.8 0.0 0.13 11.2 0.0 2.0 2 0 0 2 2 2 0 IMP dehydrogenase / GMP reductase domain TFIIA PF03153.13 KFX95174.1 - 1.3e-87 295.5 74.1 8.2e-53 180.9 33.2 2.2 1 1 1 2 2 2 2 Transcription factor IIA, alpha/beta subunit BAF1_ABF1 PF04684.13 KFX95174.1 - 4.2 6.3 19.4 8.5 5.3 19.4 1.5 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor ANAPC4_WD40 PF12894.7 KFX95176.1 - 4.1e-18 65.5 4.6 1.1e-06 28.8 0.1 4.4 2 1 1 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KFX95176.1 - 3.8e-15 56.0 20.5 0.00065 20.5 0.1 7.0 7 0 0 7 7 7 5 WD domain, G-beta repeat Ge1_WD40 PF16529.5 KFX95176.1 - 6.5e-07 28.6 0.2 0.00014 20.9 0.1 3.5 1 1 1 3 3 3 1 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 KFX95176.1 - 2e-06 27.8 0.1 0.00053 19.9 0.0 2.5 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A Methyltransf_23 PF13489.6 KFX95177.1 - 2.5e-15 56.7 0.0 3.5e-15 56.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KFX95177.1 - 1.1e-08 35.6 0.0 3e-08 34.3 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KFX95177.1 - 1e-07 31.9 0.0 1.2e-06 28.4 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KFX95177.1 - 4.7e-06 27.2 0.0 1.5e-05 25.6 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.14 KFX95177.1 - 0.00018 21.1 0.0 0.00033 20.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_12 PF08242.12 KFX95177.1 - 0.00026 21.7 0.0 0.00089 20.0 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.18 KFX95177.1 - 0.0012 18.1 0.0 0.002 17.4 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase domain Methyltransf_16 PF10294.9 KFX95177.1 - 0.0061 16.3 0.0 0.012 15.3 0.0 1.4 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_4 PF02390.17 KFX95177.1 - 0.0077 15.7 0.1 0.017 14.6 0.0 1.6 2 0 0 2 2 2 1 Putative methyltransferase FtsJ PF01728.19 KFX95177.1 - 0.01 16.0 0.0 0.016 15.3 0.0 1.2 1 0 0 1 1 1 0 FtsJ-like methyltransferase PrmA PF06325.13 KFX95177.1 - 0.039 13.3 0.0 0.057 12.8 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) CMAS PF02353.20 KFX95177.1 - 0.06 12.6 0.0 0.19 11.0 0.0 1.7 2 0 0 2 2 2 0 Mycolic acid cyclopropane synthetase SspP PF08179.12 KFX95181.1 - 0.047 14.1 0.2 0.079 13.4 0.2 1.4 1 0 0 1 1 1 0 Small acid-soluble spore protein P family AAA PF00004.29 KFX95182.1 - 1.6e-41 141.8 0.0 2.7e-41 141.1 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_ID_OB PF16450.5 KFX95182.1 - 1.3e-11 44.3 0.2 2.5e-11 43.4 0.2 1.5 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_lid_3 PF17862.1 KFX95182.1 - 1.8e-10 40.4 0.6 3.3e-10 39.6 0.6 1.4 1 0 0 1 1 1 1 AAA+ lid domain AAA_2 PF07724.14 KFX95182.1 - 1.7e-06 28.3 0.0 3.1e-06 27.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 KFX95182.1 - 4.6e-06 26.9 0.2 0.0057 16.9 0.2 2.7 1 1 0 1 1 1 1 AAA domain DUF815 PF05673.13 KFX95182.1 - 1.1e-05 24.7 0.0 1.9e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_5 PF07728.14 KFX95182.1 - 4.6e-05 23.4 0.1 0.00017 21.6 0.1 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 KFX95182.1 - 0.00026 20.8 0.0 0.00051 19.8 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 KFX95182.1 - 0.00029 21.3 0.2 0.0074 16.7 0.1 2.2 1 1 1 2 2 2 1 AAA ATPase domain AAA_18 PF13238.6 KFX95182.1 - 0.00051 20.6 0.0 0.0011 19.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain Prot_ATP_OB_N PF17758.1 KFX95182.1 - 0.0013 18.3 0.7 0.007 16.0 0.0 2.4 2 0 0 2 2 2 1 Proteasomal ATPase OB N-terminal domain AAA_28 PF13521.6 KFX95182.1 - 0.0024 18.1 0.3 0.0075 16.5 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 KFX95182.1 - 0.0026 17.9 0.0 0.027 14.6 0.0 2.2 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 KFX95182.1 - 0.012 15.6 0.2 0.63 9.9 0.1 2.6 2 1 1 3 3 3 0 NACHT domain IstB_IS21 PF01695.17 KFX95182.1 - 0.014 15.1 0.0 0.036 13.8 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_14 PF13173.6 KFX95182.1 - 0.018 15.1 0.0 0.037 14.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_3 PF07726.11 KFX95182.1 - 0.019 14.8 0.0 0.041 13.8 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) ATPase PF06745.13 KFX95182.1 - 0.032 13.6 0.1 0.51 9.6 0.1 2.2 1 1 0 2 2 2 0 KaiC TIP49 PF06068.13 KFX95182.1 - 0.039 13.1 1.6 0.07 12.3 0.1 1.9 2 1 0 2 2 2 0 TIP49 P-loop domain RNA_helicase PF00910.22 KFX95182.1 - 0.05 14.0 0.0 0.099 13.0 0.0 1.5 1 0 0 1 1 1 0 RNA helicase Mg_chelatase PF01078.21 KFX95182.1 - 0.062 12.7 0.1 0.12 11.7 0.1 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Zeta_toxin PF06414.12 KFX95182.1 - 0.07 12.4 0.0 0.18 11.0 0.0 1.6 2 0 0 2 2 2 0 Zeta toxin AAA_25 PF13481.6 KFX95182.1 - 0.11 12.1 1.3 0.55 9.8 0.4 2.4 1 1 0 2 2 2 0 AAA domain ABC_tran PF00005.27 KFX95182.1 - 0.15 12.6 0.5 1 9.9 0.5 2.4 1 1 0 1 1 1 0 ABC transporter DUF2075 PF09848.9 KFX95182.1 - 0.16 11.1 0.0 0.23 10.7 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) PhoH PF02562.16 KFX95182.1 - 0.18 11.3 0.9 0.5 9.8 0.1 1.9 2 0 0 2 2 2 0 PhoH-like protein AAA_24 PF13479.6 KFX95182.1 - 0.25 11.0 2.4 0.3 10.8 0.3 2.2 2 1 0 2 2 2 0 AAA domain Ribosomal_S7 PF00177.21 KFX95184.1 - 1.9e-36 124.9 2.4 2.4e-36 124.6 2.4 1.1 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e Ribosomal_S25 PF03297.15 KFX95185.1 - 2.5e-38 130.4 3.0 2.7e-38 130.2 3.0 1.0 1 0 0 1 1 1 1 S25 ribosomal protein MarR_2 PF12802.7 KFX95185.1 - 0.0029 17.5 0.1 0.0037 17.1 0.1 1.2 1 0 0 1 1 1 1 MarR family HTH_24 PF13412.6 KFX95185.1 - 0.0073 15.8 0.1 0.011 15.2 0.1 1.3 1 0 0 1 1 1 1 Winged helix-turn-helix DNA-binding HTH_DeoR PF08220.12 KFX95185.1 - 0.013 15.3 0.1 0.017 14.8 0.1 1.2 1 0 0 1 1 1 0 DeoR-like helix-turn-helix domain Rrf2 PF02082.20 KFX95185.1 - 0.033 14.6 0.0 0.048 14.0 0.0 1.2 1 0 0 1 1 1 0 Transcriptional regulator Cyt-b5 PF00173.28 KFX95186.1 - 1.8e-10 40.8 0.0 2.5e-10 40.3 0.0 1.3 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain DUF5504 PF17608.2 KFX95186.1 - 0.084 13.0 0.0 0.14 12.3 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5504) DEAD PF00270.29 KFX95187.1 - 2.2e-34 118.8 0.6 2.6e-16 59.9 0.0 2.5 1 1 1 2 2 2 2 DEAD/DEAH box helicase Helicase_C PF00271.31 KFX95187.1 - 1.4e-21 76.9 0.0 3.5e-21 75.6 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KFX95187.1 - 1.5e-05 25.0 0.1 0.00024 21.1 0.0 2.5 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit Menin PF05053.13 KFX95187.1 - 0.00078 17.9 3.1 0.00078 17.9 3.1 2.9 2 1 1 3 3 3 1 Menin Apt1 PF10351.9 KFX95187.1 - 0.0024 16.8 11.3 0.0024 16.8 11.3 2.7 2 1 0 2 2 2 1 Golgi-body localisation protein domain UvrD-helicase PF00580.21 KFX95187.1 - 0.59 9.6 0.0 0.59 9.6 0.0 2.6 2 0 0 2 2 2 0 UvrD/REP helicase N-terminal domain PIGA PF08288.12 KFX95188.1 - 2.5e-46 156.2 5.0 3.4e-46 155.8 1.9 2.6 3 0 0 3 3 3 1 PIGA (GPI anchor biosynthesis) Glyco_transf_4 PF13439.6 KFX95188.1 - 3.9e-29 101.8 0.5 6.3e-29 101.2 0.5 1.3 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glycos_transf_1 PF00534.20 KFX95188.1 - 4.4e-26 91.4 0.0 6.9e-26 90.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 KFX95188.1 - 4.1e-24 85.5 0.2 7.9e-24 84.6 0.2 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 KFX95188.1 - 4.2e-12 46.8 0.0 1e-11 45.6 0.0 1.7 2 0 0 2 2 2 1 Glycosyl transferase 4-like domain Glyco_trans_4_2 PF13477.6 KFX95188.1 - 3.8e-06 27.0 0.1 9.7e-06 25.7 0.1 1.6 2 0 0 2 2 2 1 Glycosyl transferase 4-like Glyco_trans_1_2 PF13524.6 KFX95188.1 - 0.00071 19.9 0.0 0.0027 18.0 0.0 2.0 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_hydro_10 PF00331.20 KFX95189.1 - 2.2e-103 345.7 0.0 2.6e-103 345.5 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 Glyco_hydro_42 PF02449.15 KFX95189.1 - 0.011 15.1 0.1 0.019 14.3 0.1 1.3 1 0 0 1 1 1 0 Beta-galactosidase FeS_assembly_P PF01883.19 KFX95189.1 - 0.072 13.3 0.1 0.16 12.1 0.1 1.6 1 0 0 1 1 1 0 Iron-sulfur cluster assembly protein NPR3 PF03666.13 KFX95190.1 - 1.3e-147 492.4 0.5 2e-147 491.8 0.2 1.5 2 0 0 2 2 2 1 Nitrogen Permease regulator of amino acid transport activity 3 CHCH PF06747.13 KFX95191.1 - 2.1e-05 24.5 0.9 3.5e-05 23.8 0.9 1.4 1 0 0 1 1 1 1 CHCH domain COX17 PF05051.13 KFX95191.1 - 0.0032 17.8 2.2 0.2 12.0 0.3 2.3 1 1 1 2 2 2 2 Cytochrome C oxidase copper chaperone (COX17) Pet191_N PF10203.9 KFX95191.1 - 0.016 15.5 2.8 0.11 12.9 3.2 1.8 1 1 1 2 2 2 0 Cytochrome c oxidase assembly protein PET191 GFA PF04828.14 KFX95192.1 - 2.2e-07 31.1 1.0 5.1e-07 29.9 0.9 1.6 1 1 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme DUF4614 PF15391.6 KFX95193.1 - 0.3 11.1 11.7 0.4 10.7 11.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4614) SPX PF03105.19 KFX95193.1 - 5.3 6.9 11.9 5.7 6.8 11.9 1.0 1 0 0 1 1 1 0 SPX domain SOG2 PF10428.9 KFX95193.1 - 6.9 5.7 14.6 7.3 5.7 14.6 1.0 1 0 0 1 1 1 0 RAM signalling pathway protein Apt1 PF10351.9 KFX95193.1 - 7.1 5.4 14.4 8 5.2 14.4 1.0 1 0 0 1 1 1 0 Golgi-body localisation protein domain Hid1 PF12722.7 KFX95193.1 - 7.9 4.5 4.6 9.2 4.3 4.6 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein UCR_Fe-S_N PF10399.9 KFX95194.1 - 6.1 6.3 0.0 2.9 7.3 0.8 6.1 5 0 0 5 5 5 0 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal Fn3-like PF14310.6 KFX95197.1 - 6.5e-26 90.2 1.6 6.5e-26 90.2 1.6 1.6 2 0 0 2 2 2 1 Fibronectin type III-like domain Glyco_hydro_3_C PF01915.22 KFX95197.1 - 1.5e-23 83.8 0.3 8.4e-23 81.4 0.1 2.2 2 1 0 2 2 2 1 Glycosyl hydrolase family 3 C-terminal domain NPCBM_assoc PF10633.9 KFX95197.1 - 0.039 14.2 0.4 0.11 12.8 0.4 1.7 1 0 0 1 1 1 0 NPCBM-associated, NEW3 domain of alpha-galactosidase MFS_1 PF07690.16 KFX95199.1 - 8.5e-42 143.3 40.1 8.5e-42 143.3 40.1 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KFX95199.1 - 1.1e-10 41.0 13.3 1.1e-10 41.0 13.3 2.4 1 1 1 2 2 2 1 Sugar (and other) transporter MFS_4 PF06779.14 KFX95199.1 - 2.2e-08 33.8 7.1 2.2e-08 33.8 7.1 2.9 2 1 1 3 3 3 1 Uncharacterised MFS-type transporter YbfB MFS_3 PF05977.13 KFX95199.1 - 0.18 10.1 7.8 0.77 8.1 7.8 2.0 1 1 0 1 1 1 0 Transmembrane secretion effector DEAD PF00270.29 KFX95200.1 - 6.8e-46 156.2 0.2 6.8e-43 146.5 0.2 2.2 2 0 0 2 2 2 2 DEAD/DEAH box helicase Helicase_C PF00271.31 KFX95200.1 - 1.3e-25 89.9 0.1 2.8e-22 79.1 0.0 3.5 4 0 0 4 4 4 1 Helicase conserved C-terminal domain ResIII PF04851.15 KFX95200.1 - 8.2e-10 38.9 0.0 1.8e-09 37.8 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 KFX95200.1 - 0.0081 16.4 1.5 0.47 10.7 1.6 2.9 2 2 0 2 2 2 1 AAA domain Helicase_RecD PF05127.14 KFX95200.1 - 0.02 14.7 0.0 0.049 13.5 0.0 1.6 2 0 0 2 2 2 0 Helicase OB_NTP_bind PF07717.16 KFX95201.1 - 7.7e-24 83.9 0.1 3e-23 82.0 0.0 2.0 2 0 0 2 2 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.23 KFX95201.1 - 3.8e-19 68.9 0.0 9.3e-19 67.7 0.0 1.6 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.31 KFX95201.1 - 2.7e-11 43.8 0.0 7.1e-11 42.4 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 KFX95201.1 - 2e-06 27.7 0.4 6.3e-06 26.1 0.2 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_22 PF13401.6 KFX95201.1 - 2.1e-06 28.0 0.0 6.7e-06 26.4 0.0 1.8 1 0 0 1 1 1 1 AAA domain SRP54 PF00448.22 KFX95201.1 - 0.00015 21.4 0.1 0.00056 19.6 0.1 1.8 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain Flavi_DEAD PF07652.14 KFX95201.1 - 0.0041 17.1 0.1 0.0098 15.9 0.1 1.6 1 0 0 1 1 1 1 Flavivirus DEAD domain AAA_19 PF13245.6 KFX95201.1 - 0.015 15.6 0.1 0.042 14.2 0.1 1.7 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 KFX95201.1 - 0.1 12.3 0.0 0.18 11.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain DUF2075 PF09848.9 KFX95201.1 - 0.17 11.1 0.0 0.28 10.4 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) PALP PF00291.25 KFX95208.1 - 0.0038 16.7 0.1 0.0053 16.2 0.1 1.2 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme FlxA PF14282.6 KFX95209.1 - 0.00094 19.1 0.8 0.0027 17.7 0.8 1.8 1 0 0 1 1 1 1 FlxA-like protein Pkinase PF00069.25 KFX95210.1 - 1.1e-08 34.8 0.0 1.6e-08 34.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.6 KFX95210.1 - 9.6e-05 21.8 0.0 0.00013 21.4 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pkinase_Tyr PF07714.17 KFX95210.1 - 0.0014 17.9 0.0 0.0021 17.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 KFX95210.1 - 0.048 13.0 0.2 0.086 12.2 0.2 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family OKR_DC_1_C PF03711.15 KFX95210.1 - 0.065 13.5 0.0 0.26 11.6 0.0 1.8 2 0 0 2 2 2 0 Orn/Lys/Arg decarboxylase, C-terminal domain Glyco_hydro_72 PF03198.14 KFX95211.1 - 1.2e-100 336.9 0.0 1.6e-100 336.5 0.0 1.0 1 0 0 1 1 1 1 Glucanosyltransferase DUF3605 PF12239.8 KFX95214.1 - 6.2e-53 179.2 0.1 3.5e-52 176.8 0.1 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF3605) FolB PF02152.18 KFX95215.1 - 1e-21 77.6 0.1 1.2e-17 64.5 0.2 2.4 2 0 0 2 2 2 2 Dihydroneopterin aldolase FAR1 PF03101.15 KFX95215.1 - 0.01 16.5 0.6 0.02 15.6 0.6 1.4 1 0 0 1 1 1 0 FAR1 DNA-binding domain Fungal_trans PF04082.18 KFX95216.1 - 1.9e-15 56.6 0.0 3.4e-15 55.8 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF3306 PF11748.8 KFX95216.1 - 0.02 15.8 0.1 0.047 14.6 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3306) ING PF12998.7 KFX95217.1 - 6.1e-20 71.7 1.7 8.8e-20 71.2 1.7 1.2 1 0 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.29 KFX95217.1 - 0.00012 21.9 7.7 0.00022 21.0 7.7 1.4 1 0 0 1 1 1 1 PHD-finger zf-RanBP PF00641.18 KFX95217.1 - 0.013 14.8 0.9 0.026 13.8 0.9 1.6 1 0 0 1 1 1 0 Zn-finger in Ran binding protein and others zf-HC5HC2H PF13771.6 KFX95217.1 - 0.15 12.3 1.0 0.33 11.2 1.0 1.6 1 0 0 1 1 1 0 PHD-like zinc-binding domain Hist_deacetyl PF00850.19 KFX95218.1 - 3e-81 273.2 0.1 4.8e-81 272.6 0.1 1.3 1 0 0 1 1 1 1 Histone deacetylase domain tRNA-synt_His PF13393.6 KFX95219.1 - 7.8e-38 130.5 0.0 2.4e-31 109.2 0.0 2.1 2 0 0 2 2 2 2 Histidyl-tRNA synthetase HGTP_anticodon PF03129.20 KFX95219.1 - 1.3e-11 44.5 0.0 2.5e-11 43.6 0.0 1.5 1 0 0 1 1 1 1 Anticodon binding domain tRNA-synt_2b PF00587.25 KFX95219.1 - 2.3e-05 24.4 0.0 3.7e-05 23.8 0.0 1.4 1 1 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) tRNA-synt_2 PF00152.20 KFX95219.1 - 0.004 16.3 0.0 0.018 14.1 0.0 1.8 2 1 0 2 2 2 1 tRNA synthetases class II (D, K and N) HGTP_anticodon2 PF12745.7 KFX95219.1 - 0.015 14.8 0.0 0.024 14.1 0.0 1.3 1 0 0 1 1 1 0 Anticodon binding domain of tRNAs POR_N PF01855.19 KFX95221.1 - 0.45 10.2 4.4 0.68 9.6 4.4 1.2 1 0 0 1 1 1 0 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg Polyketide_cyc2 PF10604.9 KFX95222.1 - 1.7e-09 38.1 5.1 9e-09 35.7 5.1 1.9 1 1 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc PF03364.20 KFX95222.1 - 0.0081 16.4 0.0 0.014 15.6 0.0 1.4 1 1 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport TcpQ PF10671.9 KFX95222.1 - 0.032 14.3 0.1 0.12 12.5 0.1 1.8 2 0 0 2 2 2 0 Toxin co-regulated pilus biosynthesis protein Q CNDH2_C PF16858.5 KFX95223.1 - 0.19 11.6 7.0 0.21 11.4 7.0 1.1 1 0 0 1 1 1 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term Paf1 PF03985.13 KFX95223.1 - 0.31 10.0 12.6 0.38 9.7 12.6 1.1 1 0 0 1 1 1 0 Paf1 Nop14 PF04147.12 KFX95223.1 - 0.7 8.0 18.9 0.76 7.9 18.9 1.1 1 0 0 1 1 1 0 Nop14-like family BUD22 PF09073.10 KFX95223.1 - 2.5 7.4 19.9 2.9 7.2 19.9 1.1 1 0 0 1 1 1 0 BUD22 Pox_RNA_Pol_19 PF05320.12 KFX95223.1 - 2.8 7.9 12.1 4 7.4 12.1 1.2 1 0 0 1 1 1 0 Poxvirus DNA-directed RNA polymerase 19 kDa subunit SDA1 PF05285.12 KFX95223.1 - 4.6 6.6 23.2 5.4 6.3 23.2 1.1 1 0 0 1 1 1 0 SDA1 Na_trans_assoc PF06512.13 KFX95223.1 - 4.9 7.4 14.6 5.7 7.2 14.6 1.2 1 0 0 1 1 1 0 Sodium ion transport-associated Aminotran_4 PF01063.19 KFX95224.1 - 6.4e-35 121.0 0.0 8.6e-35 120.6 0.0 1.2 1 0 0 1 1 1 1 Amino-transferase class IV Pkinase PF00069.25 KFX95225.1 - 1.2e-14 54.3 0.0 6.6e-14 51.9 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFX95225.1 - 5.1e-06 26.0 0.0 1.9e-05 24.1 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase DCB PF16213.5 KFX95225.1 - 0.00045 19.9 2.3 0.00046 19.9 0.1 2.1 3 0 0 3 3 3 1 Dimerisation and cyclophilin-binding domain of Mon2 ParcG PF10274.9 KFX95225.1 - 0.1 12.7 1.2 0.17 12.0 0.1 1.9 2 0 0 2 2 2 0 Parkin co-regulated protein Helicase_C PF00271.31 KFX95228.1 - 1.6e-08 34.9 0.5 2.4e-08 34.3 0.2 1.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain GRP PF07172.11 KFX95228.1 - 0.37 11.5 25.1 0.26 12.0 23.9 1.4 1 1 0 1 1 1 0 Glycine rich protein family RhlB PF12300.8 KFX95228.1 - 0.63 10.2 9.0 0.75 9.9 9.0 1.2 1 0 0 1 1 1 0 ATP-dependent RNA helicase RhlB IQCJ-SCHIP1 PF15157.6 KFX95230.1 - 0.039 13.8 0.3 0.047 13.5 0.3 1.1 1 0 0 1 1 1 0 Fusion protein IQCJ-SCHIP1 with IQ-like motif Ish1 PF10281.9 KFX95230.1 - 0.11 12.8 0.6 0.11 12.8 0.6 1.9 2 0 0 2 2 2 0 Putative stress-responsive nuclear envelope protein GFA PF04828.14 KFX95231.1 - 2.3e-19 69.5 0.1 3.4e-19 69.0 0.1 1.3 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme ADH_N PF08240.12 KFX95232.1 - 4.4e-28 97.3 1.7 6.9e-28 96.7 1.7 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Rbx_binding PF18113.1 KFX95235.1 - 0.12 12.2 0.0 0.19 11.5 0.0 1.3 1 0 0 1 1 1 0 Rubredoxin binding C-terminal domain BUD22 PF09073.10 KFX95236.1 - 4.3 6.6 36.4 4.8 6.4 36.4 1.0 1 0 0 1 1 1 0 BUD22 DNA_pol_A_exo1 PF01612.20 KFX95237.1 - 0.00028 20.6 0.0 0.00028 20.6 0.0 1.2 1 0 0 1 1 1 1 3'-5' exonuclease MCU PF04678.13 KFX95238.1 - 4.4e-27 95.3 0.1 4.4e-27 95.3 0.1 2.3 3 0 0 3 3 3 1 Mitochondrial calcium uniporter BSD PF03909.17 KFX95240.1 - 1.4e-27 95.4 5.7 2e-13 50.1 0.4 2.7 2 0 0 2 2 2 2 BSD domain PH_TFIIH PF08567.11 KFX95240.1 - 2.8e-25 88.5 0.0 7e-25 87.2 0.0 1.7 1 0 0 1 1 1 1 TFIIH p62 subunit, N-terminal domain Transket_pyr PF02779.24 KFX95241.1 - 1.9e-63 213.3 0.0 3.3e-63 212.6 0.0 1.4 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain E1_dh PF00676.20 KFX95241.1 - 4.6e-57 193.2 0.0 6.8e-57 192.7 0.0 1.3 1 0 0 1 1 1 1 Dehydrogenase E1 component OxoGdeHyase_C PF16870.5 KFX95241.1 - 9.1e-56 187.8 0.0 1.5e-55 187.1 0.0 1.3 1 0 0 1 1 1 1 2-oxoglutarate dehydrogenase C-terminal 2-oxogl_dehyd_N PF16078.5 KFX95241.1 - 2.8e-19 68.4 1.8 6.6e-19 67.2 1.8 1.7 1 0 0 1 1 1 1 2-oxoglutarate dehydrogenase N-terminus NTP_transferase PF00483.23 KFX95242.1 - 5.6e-52 176.8 0.0 9.3e-52 176.1 0.0 1.3 2 0 0 2 2 2 1 Nucleotidyl transferase Hexapep PF00132.24 KFX95242.1 - 6.4e-16 57.4 11.2 2.8e-10 39.5 2.0 3.7 1 1 2 3 3 3 3 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.7 KFX95242.1 - 1.2e-10 41.9 0.0 1.7e-10 41.5 0.0 1.2 1 0 0 1 1 1 1 MobA-like NTP transferase domain Hexapep_2 PF14602.6 KFX95242.1 - 8.4e-06 25.4 1.7 8.4e-06 25.4 1.7 3.0 3 1 0 3 3 3 1 Hexapeptide repeat of succinyl-transferase DUF4954 PF16314.5 KFX95242.1 - 2.6e-05 22.6 0.1 5.7e-05 21.5 0.0 1.5 1 1 0 1 1 1 1 Domain of unknown function (DUF4954) Anp1 PF03452.14 KFX95247.1 - 4.5e-106 354.1 0.0 5.3e-106 353.9 0.0 1.0 1 0 0 1 1 1 1 Anp1 Glycos_transf_2 PF00535.26 KFX95247.1 - 0.017 14.9 0.0 0.029 14.2 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase family 2 Peptidase_C1_2 PF03051.15 KFX95250.1 - 4.1e-153 510.3 0.0 4.7e-153 510.1 0.0 1.0 1 0 0 1 1 1 1 Peptidase C1-like family Peptidase_C1 PF00112.23 KFX95250.1 - 4.8e-08 33.3 0.1 0.0015 18.7 0.1 2.3 2 0 0 2 2 2 2 Papain family cysteine protease AraC_N PF06719.13 KFX95251.1 - 0.069 12.8 0.0 0.34 10.5 0.0 1.8 1 1 1 2 2 2 0 AraC-type transcriptional regulator N-terminus Peptidase_M19 PF01244.21 KFX95253.1 - 3.8e-59 200.4 0.0 7.7e-59 199.4 0.0 1.4 1 1 1 2 2 2 1 Membrane dipeptidase (Peptidase family M19) Amidohydro_2 PF04909.14 KFX95253.1 - 0.056 13.2 0.0 0.069 12.9 0.0 1.2 1 0 0 1 1 1 0 Amidohydrolase DUF4643 PF15485.6 KFX95255.1 - 0.1 12.4 0.0 0.11 12.4 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4643) FA_hydroxylase PF04116.13 KFX95264.1 - 7.1e-14 52.3 20.9 7.1e-14 52.3 20.9 1.6 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily XRN_M PF17846.1 KFX95264.1 - 0.36 9.7 2.1 0.49 9.3 2.1 1.1 1 0 0 1 1 1 0 Xrn1 helical domain DUF2752 PF10825.8 KFX95264.1 - 0.43 10.7 0.1 0.43 10.7 0.1 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF2752) Ank_2 PF12796.7 KFX95265.1 - 2e-14 53.9 0.7 7.9e-12 45.6 0.2 2.0 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KFX95265.1 - 2.9e-13 49.7 0.4 7.4e-06 26.1 0.0 2.9 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_4 PF13637.6 KFX95265.1 - 1.8e-12 47.5 0.7 1.6e-06 28.5 0.1 2.3 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 KFX95265.1 - 4.7e-10 39.5 0.2 5.3e-05 23.5 0.1 3.2 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.6 KFX95265.1 - 2.8e-06 27.3 0.1 0.0029 18.0 0.0 2.8 3 0 0 3 3 3 2 Ankyrin repeat DUF2236 PF09995.9 KFX95272.1 - 6.3e-35 121.4 0.0 7.9e-35 121.1 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2236) YscJ_FliF PF01514.17 KFX95272.1 - 0.014 15.1 0.0 0.02 14.6 0.0 1.2 1 0 0 1 1 1 0 Secretory protein of YscJ/FliF family Ferric_reduct PF01794.19 KFX95274.1 - 1.4e-11 44.6 5.2 1.4e-11 44.6 5.2 2.5 2 0 0 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.12 KFX95274.1 - 4.5e-08 33.1 0.0 1.4e-07 31.5 0.0 1.9 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.12 KFX95274.1 - 9.5e-05 22.6 0.0 0.00022 21.4 0.0 1.7 2 0 0 2 2 2 1 Ferric reductase NAD binding domain zf-C2H2_aberr PF17017.5 KFX95278.1 - 0.15 12.2 0.1 0.15 12.2 0.1 2.0 2 0 0 2 2 2 0 Aberrant zinc-finger zf-C2H2_4 PF13894.6 KFX95278.1 - 0.2 12.6 5.9 11 7.2 1.4 3.1 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2 PF00096.26 KFX95278.1 - 9.1 7.0 14.5 5 7.8 1.3 3.2 3 1 0 3 3 3 0 Zinc finger, C2H2 type Aldedh PF00171.22 KFX95280.1 - 5.9e-178 592.1 0.7 6.7e-178 591.9 0.7 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.11 KFX95280.1 - 0.002 17.6 0.0 0.54 9.7 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF1487) MFS_1 PF07690.16 KFX95281.1 - 3.1e-46 157.9 30.5 4e-44 151.0 20.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KFX95281.1 - 3.3e-18 65.8 25.5 3.6e-17 62.4 25.5 2.3 1 1 0 1 1 1 1 Sugar (and other) transporter TRI12 PF06609.13 KFX95281.1 - 1.6e-05 23.6 2.3 2.6e-05 22.9 2.3 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_3 PF05977.13 KFX95281.1 - 0.0024 16.3 1.3 0.0049 15.3 1.3 1.4 1 0 0 1 1 1 1 Transmembrane secretion effector PUCC PF03209.15 KFX95281.1 - 0.027 13.5 15.9 0.015 14.3 5.5 2.7 2 1 1 3 3 3 0 PUCC protein OATP PF03137.20 KFX95281.1 - 0.085 11.1 9.2 0.11 10.7 2.0 2.9 1 1 1 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family Arginase PF00491.21 KFX95282.1 - 4e-93 311.9 0.0 4.8e-93 311.7 0.0 1.0 1 0 0 1 1 1 1 Arginase family UPF0489 PF12640.7 KFX95282.1 - 0.011 15.9 0.0 0.019 15.2 0.0 1.3 1 0 0 1 1 1 0 UPF0489 domain Fungal_trans_2 PF11951.8 KFX95283.1 - 4.3e-51 173.9 8.7 5.4e-51 173.6 8.7 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KFX95283.1 - 5e-09 36.1 9.8 9.1e-09 35.3 9.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PS-DH PF14765.6 KFX95283.1 - 0.0092 15.3 0.3 0.08 12.2 0.1 2.2 2 0 0 2 2 2 1 Polyketide synthase dehydratase PSI_integrin PF17205.3 KFX95283.1 - 2.4 7.9 9.4 2.7 7.8 7.5 2.1 1 1 1 2 2 2 0 Integrin plexin domain Amidase PF01425.21 KFX95285.1 - 2e-95 320.4 0.0 4.8e-95 319.2 0.0 1.6 1 1 0 1 1 1 1 Amidase MBOAT_2 PF13813.6 KFX95286.1 - 2.4e-18 66.2 2.6 6.1e-18 64.9 2.6 1.8 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family adh_short PF00106.25 KFX95286.1 - 2e-17 63.3 0.0 3.5e-12 46.2 0.0 2.2 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KFX95286.1 - 1.3e-11 44.5 0.0 3.3e-08 33.4 0.0 2.2 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KFX95286.1 - 2e-05 24.6 0.1 4.7e-05 23.4 0.1 1.6 2 0 0 2 2 2 1 KR domain Fungal_trans PF04082.18 KFX95287.1 - 5.9e-17 61.6 0.0 1.3e-16 60.5 0.0 1.5 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KFX95287.1 - 9.3e-07 28.9 11.0 1.5e-06 28.2 11.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain p450 PF00067.22 KFX95289.1 - 1.2e-50 172.6 0.0 1.7e-50 172.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 AA_permease_2 PF13520.6 KFX95290.1 - 2.2e-55 188.2 58.5 2.7e-55 187.9 58.5 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KFX95290.1 - 1.9e-22 79.5 49.4 2.7e-22 79.0 49.4 1.1 1 0 0 1 1 1 1 Amino acid permease MgsA_C PF12002.8 KFX95314.1 - 6.1e-59 198.7 0.0 9.9e-59 198.0 0.0 1.3 1 0 0 1 1 1 1 MgsA AAA+ ATPase C terminal AAA_assoc_2 PF16193.5 KFX95314.1 - 5.6e-23 81.1 0.2 1.4e-22 79.8 0.2 1.6 1 0 0 1 1 1 1 AAA C-terminal domain AAA PF00004.29 KFX95314.1 - 2.4e-12 47.4 0.0 6e-12 46.1 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 KFX95314.1 - 4e-08 33.2 0.0 7.8e-08 32.2 0.0 1.5 1 1 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain Mg_chelatase PF01078.21 KFX95314.1 - 7.1e-06 25.5 0.1 0.04 13.3 0.0 2.2 1 1 1 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_16 PF13191.6 KFX95314.1 - 5.4e-05 23.6 0.6 0.02 15.3 0.1 3.1 2 1 0 3 3 3 1 AAA ATPase domain Sigma54_activat PF00158.26 KFX95314.1 - 6.3e-05 22.7 0.1 0.0021 17.8 0.1 2.2 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_5 PF07728.14 KFX95314.1 - 0.00019 21.5 0.1 0.016 15.2 0.0 2.9 2 1 0 2 2 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 KFX95314.1 - 0.0024 18.2 0.2 0.0086 16.4 0.1 2.0 1 1 0 1 1 1 1 AAA domain AAA_3 PF07726.11 KFX95314.1 - 0.0052 16.7 0.0 0.015 15.1 0.0 1.8 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.6 KFX95314.1 - 0.014 15.8 0.3 0.042 14.2 0.2 1.8 1 1 1 2 2 2 0 AAA domain DUF815 PF05673.13 KFX95314.1 - 0.016 14.4 0.0 0.025 13.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF815) TIP49 PF06068.13 KFX95314.1 - 0.022 14.0 0.0 0.045 13.0 0.0 1.3 1 1 0 1 1 1 0 TIP49 P-loop domain AAA_30 PF13604.6 KFX95314.1 - 0.052 13.3 0.2 0.19 11.5 0.2 1.8 1 1 0 1 1 1 0 AAA domain ResIII PF04851.15 KFX95314.1 - 0.058 13.4 0.1 5.9 6.9 0.0 2.3 1 1 1 2 2 2 0 Type III restriction enzyme, res subunit Sigma54_activ_2 PF14532.6 KFX95314.1 - 0.065 13.4 0.0 0.14 12.2 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_14 PF13173.6 KFX95314.1 - 0.083 12.9 0.0 0.15 12.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain zf-ribbon_3 PF13248.6 KFX95314.1 - 0.11 11.9 0.5 0.31 10.5 0.5 1.8 1 0 0 1 1 1 0 zinc-ribbon domain AAA_29 PF13555.6 KFX95314.1 - 0.12 12.2 0.0 4.6 7.1 0.0 2.4 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_24 PF13479.6 KFX95314.1 - 0.15 11.8 0.1 0.26 11.0 0.1 1.4 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 KFX95314.1 - 0.15 12.1 0.0 0.29 11.1 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Glyco_hydro_10 PF00331.20 KFX95315.1 - 2e-103 345.9 0.0 2.3e-103 345.6 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 LEA_6 PF10714.9 KFX95315.1 - 0.03 14.4 1.3 0.03 14.4 1.3 2.2 2 0 0 2 2 2 0 Late embryogenesis abundant protein 18 Beta-prism_lec PF16458.5 KFX95315.1 - 0.098 12.6 0.9 0.21 11.6 0.9 1.5 1 0 0 1 1 1 0 Beta-prism lectin SPT2 PF08243.11 KFX95317.1 - 3.3e-09 37.2 13.2 3.3e-09 37.2 13.2 2.2 3 0 0 3 3 3 1 SPT2 chromatin protein SET PF00856.28 KFX95318.1 - 6.5e-11 42.9 0.3 1.1e-10 42.2 0.3 1.4 1 0 0 1 1 1 1 SET domain SIL1 PF16782.5 KFX95320.1 - 1.5e-09 37.5 0.0 2.4e-09 36.8 0.0 1.4 1 0 0 1 1 1 1 Nucleotide exchange factor SIL1 Chromo PF00385.24 KFX95320.1 - 0.027 14.4 1.6 0.061 13.3 1.6 1.6 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain STT3 PF02516.14 KFX95321.1 - 5.8e-147 490.5 35.2 6.7e-142 473.8 33.7 2.1 2 0 0 2 2 2 2 Oligosaccharyl transferase STT3 subunit ATP-synt_E PF05680.12 KFX95321.1 - 1.2e-18 67.2 0.2 3.7e-18 65.7 0.2 1.8 1 0 0 1 1 1 1 ATP synthase E chain Sel1 PF08238.12 KFX95321.1 - 4.6 8.1 7.7 53 4.7 0.2 4.0 4 0 0 4 4 4 0 Sel1 repeat Cyclin PF08613.11 KFX95328.1 - 9.1e-12 45.6 0.1 1.2e-11 45.3 0.1 1.2 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.23 KFX95328.1 - 2.1e-06 27.5 0.1 4.3e-06 26.5 0.1 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain PAH PF02671.21 KFX95328.1 - 0.0042 17.2 0.0 0.0075 16.4 0.0 1.4 1 0 0 1 1 1 1 Paired amphipathic helix repeat Fungal_trans PF04082.18 KFX95330.1 - 9.7e-08 31.4 0.0 1.4e-07 30.8 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain NB-ARC PF00931.22 KFX95331.1 - 2.7e-07 30.0 0.0 4.7e-07 29.3 0.0 1.3 1 0 0 1 1 1 1 NB-ARC domain AAA_16 PF13191.6 KFX95331.1 - 2.1e-05 25.0 0.0 0.00013 22.4 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain TPR_12 PF13424.6 KFX95331.1 - 2.3e-05 24.6 1.5 0.0027 17.9 1.6 3.1 2 1 0 2 2 2 1 Tetratricopeptide repeat ANAPC3 PF12895.7 KFX95331.1 - 0.0016 18.7 0.5 0.04 14.1 0.1 2.7 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_MalT PF17874.1 KFX95331.1 - 0.027 13.8 0.9 0.084 12.2 0.1 2.1 2 1 0 2 2 2 0 MalT-like TPR region TPR_6 PF13174.6 KFX95331.1 - 0.03 14.9 0.1 18 6.3 0.0 3.6 2 0 0 2 2 2 0 Tetratricopeptide repeat DnaB_C PF03796.15 KFX95331.1 - 0.06 12.7 0.0 0.83 8.9 0.0 2.1 2 0 0 2 2 2 0 DnaB-like helicase C terminal domain ATPase_2 PF01637.18 KFX95331.1 - 0.062 13.2 0.0 0.13 12.1 0.0 1.5 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_25 PF13481.6 KFX95331.1 - 0.081 12.5 0.0 0.26 10.9 0.0 1.8 2 0 0 2 2 2 0 AAA domain TPR_7 PF13176.6 KFX95331.1 - 0.73 10.0 3.5 21 5.5 0.3 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat EST1_DNA_bind PF10373.9 KFX95332.1 - 3e-10 40.1 0.0 5.7e-10 39.1 0.0 1.4 1 0 0 1 1 1 1 Est1 DNA/RNA binding domain EST1_DNA_bind PF10373.9 KFX95339.1 - 3.5e-10 39.8 0.0 6.3e-10 39.0 0.0 1.4 1 0 0 1 1 1 1 Est1 DNA/RNA binding domain Med25_NR-box PF11244.8 KFX95339.1 - 0.017 15.5 1.4 0.049 14.0 1.4 1.7 1 0 0 1 1 1 0 Mediator complex subunit 25 C-terminal NR box-containing 14-3-3 PF00244.20 KFX95343.1 - 2.1e-08 34.0 0.1 6.4e-08 32.4 0.0 1.7 2 0 0 2 2 2 1 14-3-3 protein MSA-2c PF12238.8 KFX95343.1 - 0.21 11.6 1.7 0.27 11.2 0.9 1.6 2 0 0 2 2 2 0 Merozoite surface antigen 2c WXG100 PF06013.12 KFX95344.1 - 2.9e-06 27.4 0.1 3.8e-06 27.0 0.1 1.2 1 0 0 1 1 1 1 Proteins of 100 residues with WXG DUF2388 PF09498.10 KFX95344.1 - 0.021 14.8 0.1 0.037 14.0 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2388) DUF4806 PF16064.5 KFX95344.1 - 0.063 13.6 0.0 0.096 13.0 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4806) PilM PF07419.12 KFX95344.1 - 0.076 13.2 0.1 0.15 12.2 0.0 1.5 2 0 0 2 2 2 0 PilM Myb_DNA-bind_6 PF13921.6 KFX95345.1 - 0.00019 21.6 0.2 0.0019 18.4 0.1 2.3 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 KFX95345.1 - 0.00054 20.1 0.0 0.0013 18.9 0.0 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain Ribosomal_L1 PF00687.21 KFX95346.1 - 4.2e-45 154.0 0.2 4.8e-45 153.8 0.2 1.0 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family RRM_1 PF00076.22 KFX95347.1 - 1e-57 191.9 1.9 4e-18 65.0 0.0 5.9 6 0 0 6 6 6 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Cwf_Cwc_15 PF04889.12 KFX95347.1 - 0.0039 17.0 21.4 0.0039 17.0 21.4 3.7 5 1 0 5 5 5 1 Cwf15/Cwc15 cell cycle control protein RRM_5 PF13893.6 KFX95347.1 - 0.0094 15.5 0.0 4.3 6.9 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SET_assoc PF11767.8 KFX95347.1 - 0.011 15.3 0.1 1.2 8.9 0.0 3.3 3 0 0 3 3 3 0 Histone lysine methyltransferase SET associated RRM_7 PF16367.5 KFX95347.1 - 0.022 14.9 0.0 51 4.1 0.0 3.8 3 0 0 3 3 3 0 RNA recognition motif RRM_occluded PF16842.5 KFX95347.1 - 0.056 13.3 0.0 0.66 9.9 0.0 2.6 2 0 0 2 2 2 0 Occluded RNA-recognition motif RRM_Rrp7 PF17799.1 KFX95347.1 - 0.057 13.2 0.1 15 5.4 0.0 2.8 2 1 0 2 2 2 0 Rrp7 RRM-like N-terminal domain Rox3 PF08633.10 KFX95348.1 - 5e-66 222.9 0.2 5e-66 222.9 0.2 1.8 2 0 0 2 2 2 1 Rox3 mediator complex subunit Sas10 PF09368.10 KFX95349.1 - 6.3e-29 100.3 7.4 6.3e-29 100.3 7.4 2.4 2 0 0 2 2 2 1 Sas10 C-terminal domain Sas10_Utp3 PF04000.15 KFX95349.1 - 3e-10 40.6 0.0 3e-10 40.6 0.0 3.2 3 0 0 3 3 3 1 Sas10/Utp3/C1D family adh_short PF00106.25 KFX95350.1 - 3.7e-30 104.8 0.0 5.2e-30 104.4 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KFX95350.1 - 9.1e-20 71.2 0.0 1.2e-19 70.8 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KFX95350.1 - 7.4e-07 29.2 0.0 1.2e-06 28.6 0.0 1.4 1 0 0 1 1 1 1 KR domain THF_DHG_CYH_C PF02882.19 KFX95350.1 - 0.017 14.5 0.0 0.028 13.7 0.0 1.4 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain GDP_Man_Dehyd PF16363.5 KFX95350.1 - 0.028 13.8 0.0 0.034 13.5 0.0 1.2 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase Shikimate_DH PF01488.20 KFX95350.1 - 0.031 14.3 0.1 0.071 13.2 0.1 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase 3HCDH_N PF02737.18 KFX95350.1 - 0.13 12.2 0.2 0.18 11.6 0.2 1.2 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DOPA_dioxygen PF08883.11 KFX95352.1 - 2e-43 146.9 0.0 2.5e-43 146.6 0.0 1.1 1 0 0 1 1 1 1 Dopa 4,5-dioxygenase family Cupin_8 PF13621.6 KFX95353.1 - 7.6e-25 88.1 0.0 9.7e-25 87.7 0.0 1.2 1 0 0 1 1 1 1 Cupin-like domain Cupin_2 PF07883.11 KFX95353.1 - 3e-05 23.7 0.1 6.7e-05 22.5 0.1 1.6 1 0 0 1 1 1 1 Cupin domain JmjC PF02373.22 KFX95353.1 - 6.9e-05 23.3 0.0 0.00013 22.3 0.0 1.5 1 0 0 1 1 1 1 JmjC domain, hydroxylase Cupin_4 PF08007.12 KFX95353.1 - 0.00032 20.3 0.0 0.00084 18.9 0.0 1.6 1 0 0 1 1 1 1 Cupin superfamily protein AraC_binding PF02311.19 KFX95353.1 - 0.022 14.7 0.0 0.061 13.2 0.0 1.7 1 0 0 1 1 1 0 AraC-like ligand binding domain Cupin_3 PF05899.12 KFX95353.1 - 0.046 13.4 0.0 0.11 12.2 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF861) Cupin_1 PF00190.22 KFX95353.1 - 0.093 12.3 0.0 0.17 11.5 0.0 1.4 1 0 0 1 1 1 0 Cupin FMO-like PF00743.19 KFX95354.1 - 6.2e-10 38.1 0.2 4.2e-08 32.1 0.2 2.2 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.6 KFX95354.1 - 1.4e-07 31.0 0.0 3.1e-06 26.6 0.0 2.5 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 KFX95354.1 - 3.8e-07 30.2 0.1 1.8e-06 28.1 0.0 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 KFX95354.1 - 3.3e-06 26.6 0.0 0.023 14.0 0.0 2.7 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KFX95354.1 - 1.9e-05 24.1 0.1 0.0021 17.3 0.1 3.1 3 1 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KFX95354.1 - 0.12 11.6 0.1 0.81 8.9 0.0 2.1 2 0 0 2 2 2 0 Thi4 family Shikimate_DH PF01488.20 KFX95354.1 - 0.21 11.7 0.0 1.5 8.9 0.0 2.1 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase CK_II_beta PF01214.18 KFX95355.1 - 2.5e-75 252.3 0.0 3.8e-75 251.7 0.0 1.3 1 0 0 1 1 1 1 Casein kinase II regulatory subunit RRN3 PF05327.11 KFX95355.1 - 0.24 9.9 1.8 0.32 9.5 1.8 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 GCIP PF13324.6 KFX95355.1 - 0.25 10.9 5.0 0.075 12.6 1.8 1.6 2 0 0 2 2 2 0 Grap2 and cyclin-D-interacting PBP1_TM PF14812.6 KFX95355.1 - 0.88 10.0 8.1 1.9 8.9 2.9 2.3 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal PTPRCAP PF15713.5 KFX95355.1 - 3 8.1 7.8 26 5.1 0.0 2.2 2 0 0 2 2 2 0 Protein tyrosine phosphatase receptor type C-associated FAM176 PF14851.6 KFX95355.1 - 4.3 7.0 5.6 2.1 8.0 2.4 1.9 2 0 0 2 2 2 0 FAM176 family zf-C2H2 PF00096.26 KFX95356.1 - 1.5e-05 25.2 12.4 0.0037 17.6 1.6 2.8 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KFX95356.1 - 0.00029 21.1 3.8 0.00029 21.1 3.8 2.5 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 KFX95356.1 - 0.00081 20.0 11.3 0.079 13.8 2.9 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger TylF PF05711.11 KFX95356.1 - 0.18 11.1 0.0 0.29 10.4 0.0 1.3 1 0 0 1 1 1 0 Macrocin-O-methyltransferase (TylF) IPP-2 PF04979.14 KFX95356.1 - 1.1 10.0 6.8 0.26 12.0 2.7 2.1 2 0 0 2 2 2 0 Protein phosphatase inhibitor 2 (IPP-2) zf-H2C2_5 PF13909.6 KFX95356.1 - 1.7 8.5 7.0 2.6 7.9 0.4 3.2 3 0 0 3 3 3 0 C2H2-type zinc-finger domain Mito_carr PF00153.27 KFX95358.1 - 2.1e-36 123.7 0.2 1.5e-17 63.3 0.1 2.1 2 0 0 2 2 2 2 Mitochondrial carrier protein bZIP_1 PF00170.21 KFX95360.1 - 2.8e-09 36.9 9.2 3.2e-08 33.5 9.2 2.1 1 1 0 1 1 1 1 bZIP transcription factor tRNA_synt_1c_R2 PF04557.15 KFX95360.1 - 0.034 15.1 0.5 0.14 13.1 0.0 2.0 2 0 0 2 2 2 0 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 2 Phg_2220_C PF09524.10 KFX95360.1 - 0.067 13.3 0.3 0.11 12.6 0.3 1.3 1 0 0 1 1 1 0 Conserved phage C-terminus (Phg_2220_C) bZIP_2 PF07716.15 KFX95360.1 - 0.22 11.6 9.5 3.1 8.0 9.5 2.2 1 1 0 1 1 1 0 Basic region leucine zipper TFIIA PF03153.13 KFX95360.1 - 6.4 6.7 14.7 7.4 6.5 14.7 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PrpF PF04303.13 KFX95361.1 - 7.1e-72 242.4 6.1 7.9e-72 242.3 6.1 1.0 1 0 0 1 1 1 1 PrpF protein ketoacyl-synt PF00109.26 KFX95363.1 - 1.9e-73 247.1 0.0 2.7e-73 246.7 0.0 1.2 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 KFX95363.1 - 1.1e-30 106.1 0.0 2.2e-30 105.1 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain KAsynt_C_assoc PF16197.5 KFX95363.1 - 2.6e-16 60.1 0.0 5.2e-16 59.1 0.0 1.5 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension Thiolase_N PF00108.23 KFX95363.1 - 0.00012 21.5 0.1 0.0002 20.8 0.1 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain ACP_syn_III PF08545.10 KFX95363.1 - 0.18 11.6 0.3 0.55 10.1 0.1 1.9 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III ADH_zinc_N PF00107.26 KFX95364.1 - 5.2e-09 36.2 0.0 9.4e-09 35.3 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KFX95364.1 - 0.00088 19.1 0.2 0.0048 16.8 0.2 2.1 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain p450 PF00067.22 KFX95365.1 - 2.3e-40 138.7 0.0 2.9e-40 138.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Chlorophyllase2 PF12740.7 KFX95366.1 - 3.1e-05 23.0 0.0 4.7e-05 22.4 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase enzyme Chlorophyllase PF07224.11 KFX95366.1 - 0.00036 19.7 0.0 0.00051 19.2 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase Dioxygenase_C PF00775.21 KFX95367.1 - 5.5e-46 156.3 0.0 7.2e-46 155.9 0.0 1.2 1 0 0 1 1 1 1 Dioxygenase Dioxygenase_N PF04444.14 KFX95367.1 - 9.8e-28 95.8 0.0 1.5e-27 95.2 0.0 1.3 1 0 0 1 1 1 1 Catechol dioxygenase N terminus CarboxypepD_reg PF13620.6 KFX95367.1 - 0.00038 20.7 0.0 0.005 17.1 0.0 2.5 2 1 0 2 2 2 1 Carboxypeptidase regulatory-like domain SpaA PF17802.1 KFX95367.1 - 0.0013 19.0 0.1 0.0025 18.1 0.1 1.4 1 0 0 1 1 1 1 Prealbumin-like fold domain SdrD_B PF17210.3 KFX95367.1 - 0.09 13.0 0.1 0.63 10.3 0.0 2.1 1 1 1 2 2 2 0 SdrD B-like domain Lactonase PF10282.9 KFX95368.1 - 2.2e-16 60.1 0.0 3.1e-16 59.6 0.0 1.2 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller DUF3471 PF11954.8 KFX95368.1 - 0.033 14.7 0.0 9.2 6.8 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3471) DUF4394 PF14339.6 KFX95368.1 - 0.07 12.5 0.0 0.2 11.0 0.0 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4394) OTT_1508_deam PF14441.6 KFX95371.1 - 4.8e-20 71.3 0.2 9.9e-20 70.3 0.2 1.6 1 0 0 1 1 1 1 OTT_1508-like deaminase Epimerase PF01370.21 KFX95373.1 - 1.4e-15 57.4 0.0 2.7e-15 56.5 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KFX95373.1 - 7.5e-13 48.6 0.0 1.4e-11 44.4 0.0 2.0 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.12 KFX95373.1 - 3.9e-08 32.8 0.0 2.8e-05 23.4 0.0 2.1 2 0 0 2 2 2 2 Male sterility protein 3Beta_HSD PF01073.19 KFX95373.1 - 3.8e-05 22.8 0.0 0.0001 21.4 0.0 1.7 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 KFX95373.1 - 0.0016 18.3 0.0 0.0062 16.5 0.0 1.9 1 1 0 1 1 1 1 NAD(P)H-binding KR PF08659.10 KFX95373.1 - 0.0039 17.1 0.1 0.13 12.1 0.0 2.2 2 0 0 2 2 2 1 KR domain NmrA PF05368.13 KFX95373.1 - 0.015 14.9 0.1 0.038 13.5 0.1 1.7 1 1 0 1 1 1 0 NmrA-like family Polysacc_synt_2 PF02719.15 KFX95373.1 - 0.13 11.4 0.0 0.24 10.5 0.0 1.4 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein SH3_3 PF08239.11 KFX95374.1 - 0.00038 20.7 0.0 0.00091 19.5 0.0 1.6 1 0 0 1 1 1 1 Bacterial SH3 domain Stomagen PF16851.5 KFX95374.1 - 0.034 14.2 1.1 0.41 10.7 0.2 2.4 2 0 0 2 2 2 0 Stomagen ABC_tran PF00005.27 KFX95375.1 - 3.4e-39 134.5 0.0 1.6e-18 67.5 0.0 2.4 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 KFX95375.1 - 2e-25 90.0 10.9 2e-25 90.0 10.9 2.7 3 0 0 3 3 2 1 ABC transporter transmembrane region SMC_N PF02463.19 KFX95375.1 - 3e-10 39.9 1.1 0.035 13.5 0.0 4.3 4 0 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 KFX95375.1 - 3.8e-10 40.1 7.2 0.019 14.8 0.1 4.3 2 2 2 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 KFX95375.1 - 2.6e-07 31.0 0.1 0.016 15.5 0.0 2.9 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.6 KFX95375.1 - 1.6e-06 27.7 0.9 0.05 13.3 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain T2SSE PF00437.20 KFX95375.1 - 3.9e-06 26.1 0.0 0.003 16.6 0.0 2.3 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_16 PF13191.6 KFX95375.1 - 2.3e-05 24.9 0.1 0.072 13.5 0.0 2.7 2 0 0 2 2 2 2 AAA ATPase domain RsgA_GTPase PF03193.16 KFX95375.1 - 2.3e-05 24.4 0.2 0.043 13.7 0.1 2.4 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 KFX95375.1 - 5.4e-05 23.2 0.2 0.32 11.1 0.0 2.5 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_23 PF13476.6 KFX95375.1 - 9.7e-05 23.0 0.8 0.38 11.2 0.1 2.2 2 0 0 2 2 2 2 AAA domain Dynamin_N PF00350.23 KFX95375.1 - 0.00012 22.2 0.4 0.12 12.4 0.0 2.3 2 0 0 2 2 2 2 Dynamin family AAA_18 PF13238.6 KFX95375.1 - 0.00042 20.9 0.0 0.12 13.0 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_15 PF13175.6 KFX95375.1 - 0.00088 19.1 0.1 0.95 9.1 0.0 2.2 2 0 0 2 2 2 2 AAA ATPase domain DUF87 PF01935.17 KFX95375.1 - 0.0012 19.0 1.7 0.078 13.1 0.0 2.3 2 0 0 2 2 2 1 Helicase HerA, central domain IstB_IS21 PF01695.17 KFX95375.1 - 0.0015 18.3 0.3 15 5.3 0.0 3.9 4 0 0 4 4 4 0 IstB-like ATP binding protein AAA_33 PF13671.6 KFX95375.1 - 0.0015 18.7 0.4 0.25 11.5 0.2 2.5 2 0 0 2 2 2 1 AAA domain AAA_7 PF12775.7 KFX95375.1 - 0.0025 17.3 0.1 1.2 8.7 0.0 2.3 2 0 0 2 2 2 1 P-loop containing dynein motor region FtsK_SpoIIIE PF01580.18 KFX95375.1 - 0.0032 16.9 0.1 0.75 9.1 0.0 2.3 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA PF00004.29 KFX95375.1 - 0.0038 17.7 0.1 0.63 10.5 0.0 2.9 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.6 KFX95375.1 - 0.0063 16.1 0.2 3.1 7.3 0.0 2.5 2 0 0 2 2 2 1 AAA domain DUF815 PF05673.13 KFX95375.1 - 0.016 14.4 0.0 7.6 5.6 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF815) SbcCD_C PF13558.6 KFX95375.1 - 0.017 15.4 3.7 1.6 9.0 0.5 3.6 3 1 0 3 3 2 0 Putative exonuclease SbcCD, C subunit ATP_bind_1 PF03029.17 KFX95375.1 - 0.02 14.7 0.2 0.14 11.9 0.2 2.1 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein cobW PF02492.19 KFX95375.1 - 0.021 14.4 1.5 0.43 10.2 0.3 2.5 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Adeno_IVa2 PF02456.15 KFX95375.1 - 0.029 13.2 0.1 4.6 5.9 0.0 2.2 2 0 0 2 2 2 0 Adenovirus IVa2 protein NACHT PF05729.12 KFX95375.1 - 0.044 13.7 0.2 13 5.7 0.0 2.7 2 0 0 2 2 2 0 NACHT domain RNA_helicase PF00910.22 KFX95375.1 - 0.055 13.9 0.1 5.2 7.5 0.0 2.5 2 0 0 2 2 2 0 RNA helicase Mg_chelatase PF01078.21 KFX95375.1 - 0.058 12.8 0.5 12 5.2 0.0 3.0 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI AAA_30 PF13604.6 KFX95375.1 - 0.067 12.9 0.1 1 9.0 0.1 2.3 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 KFX95375.1 - 0.073 12.3 0.1 1.5 8.0 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin PduV-EutP PF10662.9 KFX95375.1 - 0.11 12.3 0.6 0.81 9.4 0.0 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_10 PF12846.7 KFX95375.1 - 0.12 11.3 0.1 1.2 7.9 0.0 2.1 2 0 0 2 2 2 0 AAA-like domain TsaE PF02367.17 KFX95375.1 - 0.15 12.1 0.0 2.5 8.1 0.0 2.3 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Guanylate_kin PF00625.21 KFX95375.1 - 0.16 11.6 0.0 0.39 10.4 0.0 1.6 1 0 0 1 1 1 0 Guanylate kinase CLP1_P PF16575.5 KFX95375.1 - 0.23 11.3 0.8 1.5 8.6 0.0 2.2 2 0 0 2 2 2 0 mRNA cleavage and polyadenylation factor CLP1 P-loop SHR3_chaperone PF08229.11 KFX95375.1 - 3.9 6.4 7.7 2.3 7.2 1.9 2.5 2 0 0 2 2 2 0 ER membrane protein SH3 FAD_binding_3 PF01494.19 KFX95376.1 - 2.4e-16 60.0 0.4 1.1e-14 54.5 0.3 2.7 2 1 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.6 KFX95376.1 - 0.0023 18.2 0.0 0.0095 16.1 0.0 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Ank_2 PF12796.7 KFX95377.1 - 5.8e-48 161.4 3.9 9.2e-15 55.0 0.0 9.9 5 2 5 11 11 11 8 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KFX95377.1 - 1.3e-38 130.8 4.1 1.1e-05 25.9 0.0 11.9 9 4 5 14 14 14 9 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFX95377.1 - 6.5e-35 115.2 7.6 0.0025 18.2 0.1 15.9 17 1 1 18 18 18 6 Ankyrin repeat Ank PF00023.30 KFX95377.1 - 1.2e-25 88.8 11.8 0.006 17.0 0.3 13.8 16 0 0 16 16 16 6 Ankyrin repeat Ank_5 PF13857.6 KFX95377.1 - 8.8e-17 61.0 5.4 0.0038 17.5 0.1 9.7 8 2 2 10 10 10 4 Ankyrin repeats (many copies) Clr5 PF14420.6 KFX95377.1 - 1.5e-15 57.1 0.2 3.5e-15 56.0 0.2 1.7 1 0 0 1 1 1 1 Clr5 domain TGS PF02824.21 KFX95377.1 - 0.088 12.9 0.0 0.3 11.2 0.0 1.9 2 0 0 2 2 2 0 TGS domain Fungal_trans PF04082.18 KFX95379.1 - 9.9e-20 70.7 0.8 1.8e-19 69.8 0.8 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.26 KFX95379.1 - 0.0046 17.3 16.3 0.084 13.4 8.1 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFX95379.1 - 0.008 16.9 13.1 0.12 13.3 6.4 2.9 2 0 0 2 2 2 2 C2H2-type zinc finger Sugar_tr PF00083.24 KFX95380.1 - 1.7e-84 284.3 29.1 1.9e-84 284.1 29.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KFX95380.1 - 6.8e-27 94.3 42.2 6.3e-26 91.1 25.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1270 PF06900.11 KFX95380.1 - 0.057 13.8 0.2 0.057 13.8 0.2 3.6 4 0 0 4 4 4 0 Protein of unknown function (DUF1270) TauD PF02668.16 KFX95381.1 - 3.3e-44 151.7 0.0 4.3e-44 151.3 0.0 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Peptidase_M35 PF02102.15 KFX95382.1 - 6e-92 308.3 18.5 7e-92 308.1 18.5 1.0 1 0 0 1 1 1 1 Deuterolysin metalloprotease (M35) family Aspzincin_M35 PF14521.6 KFX95382.1 - 1.5e-40 139.1 6.3 2.5e-40 138.4 6.3 1.4 1 0 0 1 1 1 1 Lysine-specific metallo-endopeptidase HRXXH PF13933.6 KFX95382.1 - 3.1e-06 26.9 2.6 3.1e-06 26.9 2.6 1.7 2 1 0 2 2 2 1 Putative peptidase family DUF1772 PF08592.11 KFX95384.1 - 1e-33 116.6 6.0 1.3e-33 116.2 6.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1772) TMEM237 PF15383.6 KFX95384.1 - 0.0014 17.8 0.3 0.002 17.2 0.3 1.2 1 0 0 1 1 1 1 Transmembrane protein 237 Erv26 PF04148.13 KFX95384.1 - 0.099 12.5 0.0 0.12 12.2 0.0 1.2 1 0 0 1 1 1 0 Transmembrane adaptor Erv26 Aldedh PF00171.22 KFX95385.1 - 9.8e-136 452.9 1.1 1.2e-135 452.7 1.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Fungal_trans PF04082.18 KFX95388.1 - 2.1e-33 115.5 0.2 3.7e-33 114.7 0.2 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KFX95388.1 - 8.8e-05 22.5 13.6 0.00016 21.7 13.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ABC_tran PF00005.27 KFX95389.1 - 2.7e-42 144.5 2.1 2e-20 73.7 0.0 4.1 4 1 0 4 4 2 2 ABC transporter AAA_21 PF13304.6 KFX95389.1 - 1.1e-16 61.5 6.7 0.00021 21.2 0.0 4.5 4 0 0 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 KFX95389.1 - 2.9e-08 33.4 1.6 0.035 13.5 0.0 4.1 2 2 0 3 3 3 2 RecF/RecN/SMC N terminal domain ABC_tran_Xtn PF12848.7 KFX95389.1 - 2.1e-07 30.9 2.9 2.1e-07 30.9 2.9 2.0 2 0 0 2 2 2 1 ABC transporter MMR_HSR1 PF01926.23 KFX95389.1 - 9e-07 29.0 0.1 0.031 14.4 0.0 3.8 4 0 0 4 4 3 2 50S ribosome-binding GTPase AAA_29 PF13555.6 KFX95389.1 - 1.5e-06 27.8 0.5 0.002 17.9 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_30 PF13604.6 KFX95389.1 - 2e-06 27.7 0.4 0.05 13.3 0.0 3.7 3 0 0 3 3 3 2 AAA domain AAA_28 PF13521.6 KFX95389.1 - 2e-05 24.9 0.2 0.33 11.2 0.0 3.3 2 1 0 2 2 2 2 AAA domain AAA_22 PF13401.6 KFX95389.1 - 3.5e-05 24.1 1.4 1.7 9.0 0.0 3.9 3 2 0 3 3 3 2 AAA domain AAA_18 PF13238.6 KFX95389.1 - 5.4e-05 23.7 0.0 0.09 13.3 0.0 3.1 2 2 0 2 2 2 1 AAA domain AAA_16 PF13191.6 KFX95389.1 - 7.4e-05 23.2 6.3 0.049 14.0 0.1 3.4 2 1 0 2 2 2 2 AAA ATPase domain AAA_23 PF13476.6 KFX95389.1 - 0.00021 21.8 14.2 0.0099 16.4 2.1 3.3 3 1 0 3 3 3 2 AAA domain NACHT PF05729.12 KFX95389.1 - 0.00069 19.6 0.0 0.21 11.5 0.0 2.7 3 0 0 3 3 2 1 NACHT domain DUF87 PF01935.17 KFX95389.1 - 0.0016 18.6 3.3 0.13 12.4 0.0 3.2 3 0 0 3 3 3 1 Helicase HerA, central domain Thymidylate_kin PF02223.17 KFX95389.1 - 0.0052 16.5 0.0 0.38 10.4 0.0 2.5 2 0 0 2 2 2 1 Thymidylate kinase RsgA_GTPase PF03193.16 KFX95389.1 - 0.007 16.3 0.0 5.8 6.8 0.0 2.7 2 0 0 2 2 2 0 RsgA GTPase MobB PF03205.14 KFX95389.1 - 0.0072 16.2 0.1 1.1 9.2 0.2 2.8 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B NTPase_1 PF03266.15 KFX95389.1 - 0.013 15.4 0.0 5.8 6.8 0.0 3.2 4 0 0 4 4 2 0 NTPase Zeta_toxin PF06414.12 KFX95389.1 - 0.016 14.5 0.0 5.2 6.3 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin Arf PF00025.21 KFX95389.1 - 0.027 13.9 0.1 2.4 7.6 0.1 2.5 2 0 0 2 2 2 0 ADP-ribosylation factor family cobW PF02492.19 KFX95389.1 - 0.04 13.5 0.3 2.7 7.6 0.3 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain FtsK_SpoIIIE PF01580.18 KFX95389.1 - 0.041 13.2 0.1 0.67 9.3 0.0 2.4 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_33 PF13671.6 KFX95389.1 - 0.043 14.0 0.2 9.2 6.4 0.0 3.2 3 0 0 3 3 3 0 AAA domain MeaB PF03308.16 KFX95389.1 - 0.05 12.6 1.2 0.66 8.9 0.0 2.7 3 0 0 3 3 3 0 Methylmalonyl Co-A mutase-associated GTPase MeaB NB-ARC PF00931.22 KFX95389.1 - 0.052 12.7 4.1 7.7 5.6 0.0 3.9 4 0 0 4 4 4 0 NB-ARC domain SRP54 PF00448.22 KFX95389.1 - 0.056 13.1 0.0 2.8 7.5 0.0 2.6 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_5 PF07728.14 KFX95389.1 - 0.071 13.1 0.5 4.4 7.3 0.0 3.2 3 0 0 3 3 2 0 AAA domain (dynein-related subfamily) AAA_15 PF13175.6 KFX95389.1 - 0.073 12.8 8.4 0.095 12.4 0.0 3.1 4 0 0 4 4 4 0 AAA ATPase domain G-alpha PF00503.20 KFX95389.1 - 0.075 12.2 0.1 0.31 10.2 0.0 1.9 2 0 0 2 2 2 0 G-protein alpha subunit COG2 PF06148.11 KFX95389.1 - 0.083 13.0 0.1 0.73 9.9 0.0 2.5 3 0 0 3 3 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Dynamin_N PF00350.23 KFX95389.1 - 0.1 12.7 1.5 14 5.7 0.1 3.1 3 1 0 3 3 2 0 Dynamin family RNA_helicase PF00910.22 KFX95389.1 - 0.15 12.5 0.0 14 6.2 0.0 2.4 2 0 0 2 2 2 0 RNA helicase Castor_Poll_mid PF06241.12 KFX95389.1 - 0.17 11.9 0.0 0.42 10.6 0.0 1.6 1 0 0 1 1 1 0 Castor and Pollux, part of voltage-gated ion channel Cep57_MT_bd PF06657.13 KFX95389.1 - 0.72 10.3 4.7 22 5.6 0.1 4.0 4 0 0 4 4 4 0 Centrosome microtubule-binding domain of Cep57 MFS_1 PF07690.16 KFX95391.1 - 5.3e-20 71.6 51.9 1.2e-18 67.2 29.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 KFX95391.1 - 1.2e-06 27.4 5.7 1.2e-06 27.4 5.7 3.2 2 1 2 4 4 4 3 MFS/sugar transport protein Actin PF00022.19 KFX95396.1 - 7.7e-22 77.5 0.0 2.4e-19 69.2 0.0 2.8 2 1 0 2 2 2 2 Actin Actin_micro PF17003.5 KFX95396.1 - 5.3e-11 42.3 0.1 1e-05 24.9 0.1 2.3 2 0 0 2 2 2 2 Putative actin-like family MreB_Mbl PF06723.13 KFX95396.1 - 0.036 12.9 0.1 0.66 8.7 0.0 2.1 2 0 0 2 2 2 0 MreB/Mbl protein FtsA PF14450.6 KFX95396.1 - 0.072 13.5 0.0 0.15 12.5 0.0 1.7 1 1 0 1 1 1 0 Cell division protein FtsA DUF2114 PF09887.9 KFX95396.1 - 0.093 11.2 0.1 0.13 10.7 0.1 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2114) Arf PF00025.21 KFX95397.1 - 1.6e-73 245.9 0.0 1.8e-73 245.7 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 KFX95397.1 - 2.9e-14 53.3 0.0 3.9e-14 52.9 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 KFX95397.1 - 8.2e-13 48.2 0.0 1e-12 47.9 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.20 KFX95397.1 - 1.4e-10 40.9 0.4 1.8e-06 27.3 0.0 2.4 1 1 1 2 2 2 2 G-protein alpha subunit Ras PF00071.22 KFX95397.1 - 2.4e-10 40.2 0.0 2.9e-10 40.0 0.0 1.1 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.12 KFX95397.1 - 1.5e-08 34.3 0.0 1.9e-08 34.0 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 KFX95397.1 - 1e-06 28.8 0.0 1.8e-06 28.0 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 KFX95397.1 - 0.00086 18.9 0.0 0.07 12.7 0.0 2.1 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain FeoB_N PF02421.18 KFX95397.1 - 0.0094 15.5 0.5 0.034 13.7 0.5 1.9 1 1 0 1 1 1 1 Ferrous iron transport protein B AAA_18 PF13238.6 KFX95397.1 - 0.13 12.9 0.1 0.26 11.8 0.1 1.5 1 1 0 1 1 1 0 AAA domain Paf1 PF03985.13 KFX95398.1 - 4.5e-79 266.4 0.1 5.2e-79 266.2 0.1 1.0 1 0 0 1 1 1 1 Paf1 Rer1 PF03248.13 KFX95399.1 - 4.4e-79 264.2 3.1 5e-79 264.0 3.1 1.0 1 0 0 1 1 1 1 Rer1 family Helo_like_N PF17111.5 KFX95400.1 - 0.00014 21.3 5.7 0.00037 19.9 1.1 2.7 2 1 1 3 3 3 1 Fungal N-terminal domain of STAND proteins SPATA24 PF15175.6 KFX95400.1 - 0.016 15.1 0.0 0.038 13.9 0.0 1.6 1 0 0 1 1 1 0 Spermatogenesis-associated protein 24 FlgM PF04316.13 KFX95400.1 - 0.071 13.5 0.5 0.4 11.1 0.1 2.5 2 0 0 2 2 2 0 Anti-sigma-28 factor, FlgM Chol_subst-bind PF09129.11 KFX95400.1 - 0.1 11.5 0.0 0.26 10.2 0.0 1.6 1 0 0 1 1 1 0 Cholesterol oxidase, substrate-binding Prefoldin_2 PF01920.20 KFX95400.1 - 0.14 12.1 2.0 3 7.8 0.4 2.7 2 0 0 2 2 2 0 Prefoldin subunit OrsD PF12013.8 KFX95402.1 - 6.8e-20 71.6 3.4 1.9e-09 38.0 1.8 2.9 2 0 0 2 2 2 2 Orsellinic acid/F9775 biosynthesis cluster protein D zf-C2H2_2 PF12756.7 KFX95402.1 - 0.037 14.4 6.2 0.13 12.6 0.2 3.4 3 1 0 3 3 3 0 C2H2 type zinc-finger (2 copies) Ebp2 PF05890.12 KFX95404.1 - 6.1e-23 81.7 0.7 6.1e-23 81.7 0.7 2.0 2 0 0 2 2 2 2 Eukaryotic rRNA processing protein EBP2 Gly_kinase PF02595.15 KFX95404.1 - 0.039 13.0 0.1 0.072 12.1 0.1 1.4 2 0 0 2 2 2 0 Glycerate kinase family BUD22 PF09073.10 KFX95404.1 - 0.06 12.7 14.2 0.069 12.5 14.2 1.1 1 0 0 1 1 1 0 BUD22 Pmp3 PF01679.17 KFX95428.1 - 3.3e-19 68.8 8.7 5.2e-19 68.2 8.7 1.3 1 0 0 1 1 1 1 Proteolipid membrane potential modulator Glycogen_syn PF05693.13 KFX95429.1 - 0 1131.7 0.0 1.5e-182 608.5 0.0 2.0 2 0 0 2 2 2 2 Glycogen synthase Glyco_transf_4 PF13439.6 KFX95429.1 - 2.4e-06 27.7 0.1 5.9e-05 23.1 0.2 2.5 2 0 0 2 2 2 1 Glycosyltransferase Family 4 Glyco_trans_1_4 PF13692.6 KFX95429.1 - 4.1e-05 24.0 0.0 0.016 15.6 0.0 2.6 2 0 0 2 2 2 2 Glycosyl transferases group 1 Glyco_transf_5 PF08323.11 KFX95429.1 - 5.5e-05 23.0 0.0 0.00011 22.0 0.0 1.4 1 0 0 1 1 1 1 Starch synthase catalytic domain Glyco_trans_4_4 PF13579.6 KFX95429.1 - 0.00011 22.6 0.1 0.00043 20.8 0.1 2.1 2 1 0 2 2 2 1 Glycosyl transferase 4-like domain Glycos_transf_1 PF00534.20 KFX95429.1 - 0.00017 21.2 0.0 0.0036 16.9 0.0 2.3 2 0 0 2 2 2 1 Glycosyl transferases group 1 Aminotran_1_2 PF00155.21 KFX95430.1 - 1.1e-80 271.6 0.0 1.3e-80 271.3 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 KFX95430.1 - 0.00016 20.8 0.1 0.0022 17.0 0.0 2.1 2 0 0 2 2 2 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.20 KFX95430.1 - 0.00065 18.3 0.0 0.0011 17.6 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme ELFV_dehydrog_N PF02812.18 KFX95430.1 - 0.055 13.4 0.0 0.13 12.1 0.0 1.6 1 0 0 1 1 1 0 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain DegT_DnrJ_EryC1 PF01041.17 KFX95430.1 - 0.15 11.3 1.1 0.43 9.8 1.1 1.6 1 1 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family GFA PF04828.14 KFX95431.1 - 0.014 15.7 0.0 0.027 14.8 0.0 1.4 1 0 0 1 1 1 0 Glutathione-dependent formaldehyde-activating enzyme Crystallin PF00525.18 KFX95431.1 - 0.14 12.3 0.0 0.3 11.3 0.0 1.5 1 0 0 1 1 1 0 Alpha crystallin A chain, N terminal M20_dimer PF07687.14 KFX95432.1 - 9.8e-06 25.4 0.1 0.0001 22.2 0.1 2.3 2 1 0 2 2 2 1 Peptidase dimerisation domain Peptidase_M20 PF01546.28 KFX95432.1 - 3.5e-05 23.6 0.0 4.7e-05 23.2 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Ribosomal_L28e PF01778.17 KFX95436.1 - 3.3e-18 66.5 0.3 3.5e-18 66.4 0.3 1.0 1 0 0 1 1 1 1 Ribosomal L28e protein family Sec1 PF00995.23 KFX95443.1 - 1.6e-56 192.7 0.1 1.9e-56 192.5 0.1 1.0 1 0 0 1 1 1 1 Sec1 family DUF61 PF01886.16 KFX95443.1 - 0.18 11.8 0.5 11 6.1 0.0 3.2 3 1 0 3 3 3 0 Protein of unknown function DUF61 Amino_oxidase PF01593.24 KFX95444.1 - 1.4e-80 271.8 0.1 2.1e-67 228.4 0.0 2.3 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase SWIRM PF04433.17 KFX95444.1 - 7.5e-13 48.6 0.1 1.6e-12 47.6 0.1 1.6 1 0 0 1 1 1 1 SWIRM domain HMG_box PF00505.19 KFX95444.1 - 7.7e-09 35.8 0.2 2.4e-08 34.3 0.2 1.9 1 0 0 1 1 1 1 HMG (high mobility group) box NAD_binding_8 PF13450.6 KFX95444.1 - 1.2e-06 28.6 0.7 3e-06 27.4 0.2 1.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain HMG_box_2 PF09011.10 KFX95444.1 - 5.8e-06 26.8 0.2 1.2e-05 25.8 0.2 1.5 1 0 0 1 1 1 1 HMG-box domain Pyr_redox_2 PF07992.14 KFX95444.1 - 0.00087 18.6 0.0 0.0076 15.5 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KFX95444.1 - 0.006 16.2 0.1 0.011 15.4 0.1 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase Senescence_reg PF04520.13 KFX95444.1 - 0.074 13.9 1.2 0.2 12.5 1.2 1.7 1 0 0 1 1 1 0 Senescence regulator ADH_N PF08240.12 KFX95453.1 - 1.6e-26 92.3 1.5 2.8e-26 91.5 0.5 1.9 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KFX95453.1 - 9.8e-16 57.9 2.0 9.1e-15 54.8 2.0 2.2 1 1 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 KFX95453.1 - 9.3e-09 35.1 2.0 3.9e-05 23.2 0.3 2.3 2 0 0 2 2 2 2 Glucose dehydrogenase C-terminus AlaDh_PNT_C PF01262.21 KFX95453.1 - 0.011 15.1 1.6 0.021 14.1 1.6 1.5 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Shikimate_DH PF01488.20 KFX95453.1 - 0.032 14.3 0.0 0.073 13.1 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase UDPG_MGDP_dh_N PF03721.14 KFX95453.1 - 0.077 12.6 0.0 0.17 11.4 0.0 1.5 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NAD_binding_8 PF13450.6 KFX95453.1 - 0.12 12.7 0.3 0.48 10.7 0.2 2.1 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Ank_2 PF12796.7 KFX95454.1 - 1.6e-94 310.6 46.8 3.5e-16 59.5 0.8 8.2 1 1 8 10 10 10 10 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KFX95454.1 - 4.7e-64 212.0 15.5 4.9e-09 36.6 0.1 11.8 6 4 6 12 12 12 9 Ankyrin repeats (many copies) Ank PF00023.30 KFX95454.1 - 1.3e-57 189.8 33.5 1.4e-05 25.3 0.0 15.7 14 1 1 15 15 15 14 Ankyrin repeat Ank_3 PF13606.6 KFX95454.1 - 4.9e-45 146.3 19.6 0.007 16.8 0.0 16.6 16 0 0 16 16 16 11 Ankyrin repeat Ank_5 PF13857.6 KFX95454.1 - 3.2e-40 135.7 25.0 3.3e-07 30.5 0.1 10.9 6 4 3 11 11 11 8 Ankyrin repeats (many copies) NACHT PF05729.12 KFX95454.1 - 3.4e-06 27.1 0.1 1.2e-05 25.3 0.0 2.0 1 1 1 2 2 2 1 NACHT domain AAA_22 PF13401.6 KFX95454.1 - 0.0078 16.5 0.0 0.04 14.2 0.0 2.2 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KFX95454.1 - 0.015 15.7 0.1 0.34 11.3 0.0 3.0 2 0 0 2 2 2 0 AAA ATPase domain GATase PF00117.28 KFX95455.1 - 1.7e-46 158.4 0.0 2.4e-46 157.9 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I CPSase_sm_chain PF00988.22 KFX95455.1 - 2.2e-45 153.6 0.0 4.3e-45 152.6 0.0 1.5 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain Leader_CPA1 PF08252.11 KFX95455.1 - 4.7e-13 48.3 0.1 8.5e-13 47.4 0.1 1.4 1 0 0 1 1 1 1 arg-2/CPA1 leader peptide Peptidase_C26 PF07722.13 KFX95455.1 - 2e-06 27.7 0.2 3.7e-05 23.6 0.2 2.3 1 1 0 1 1 1 1 Peptidase C26 DJ-1_PfpI PF01965.24 KFX95455.1 - 0.0043 16.9 0.0 0.0073 16.1 0.0 1.3 1 0 0 1 1 1 1 DJ-1/PfpI family Dak1_2 PF13684.6 KFX95456.1 - 0.01 15.0 1.1 0.012 14.7 1.1 1.0 1 0 0 1 1 1 1 Dihydroxyacetone kinase family Ank_2 PF12796.7 KFX95474.1 - 6.3e-24 84.4 0.4 3.8e-06 27.4 0.1 5.2 3 2 1 5 5 5 4 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KFX95474.1 - 2.8e-12 45.7 2.5 0.024 15.2 0.0 7.2 7 0 0 7 7 7 2 Ankyrin repeat Ank_4 PF13637.6 KFX95474.1 - 1.3e-11 44.8 6.2 2.6e-05 24.7 0.0 6.6 4 1 3 8 8 8 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 KFX95474.1 - 1.4e-07 31.6 2.5 0.38 11.1 0.0 5.8 3 3 3 6 6 6 1 Ankyrin repeats (many copies) AAA_16 PF13191.6 KFX95474.1 - 1.8e-07 31.7 0.0 5.7e-07 30.1 0.0 1.9 1 0 0 1 1 1 1 AAA ATPase domain NACHT PF05729.12 KFX95474.1 - 4.2e-06 26.8 0.0 9.5e-06 25.6 0.0 1.6 1 0 0 1 1 1 1 NACHT domain Ank PF00023.30 KFX95474.1 - 2.4e-05 24.6 4.0 3.2 8.4 0.0 6.5 6 0 0 6 6 6 1 Ankyrin repeat AAA_22 PF13401.6 KFX95474.1 - 0.00022 21.5 0.0 0.00056 20.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 KFX95474.1 - 0.16 12.4 1.1 0.48 10.9 0.2 2.3 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Trehalase PF01204.18 KFX95476.1 - 1.7e-190 634.2 0.1 2.2e-190 633.9 0.1 1.1 1 0 0 1 1 1 1 Trehalase Trehalase_Ca-bi PF07492.11 KFX95476.1 - 2.4e-18 65.6 1.5 4.2e-18 64.7 1.5 1.4 1 0 0 1 1 1 1 Neutral trehalase Ca2+ binding domain FTA2 PF13095.6 KFX95477.1 - 7.2e-05 22.5 0.0 7.4e-05 22.5 0.0 1.0 1 0 0 1 1 1 1 Kinetochore Sim4 complex subunit FTA2 Mad3_BUB1_I PF08311.12 KFX95491.1 - 9.4e-43 145.1 0.0 2.1e-42 144.0 0.0 1.6 1 0 0 1 1 1 1 Mad3/BUB1 homology region 1 Pkinase PF00069.25 KFX95491.1 - 1.6e-08 34.2 0.0 8.6e-08 31.9 0.0 2.0 2 0 0 2 2 2 1 Protein kinase domain Mad3_BUB1_II PF08171.11 KFX95491.1 - 1.7e-05 24.9 0.0 5e-05 23.4 0.0 1.9 1 0 0 1 1 1 1 Mad3/BUB1 homology region 2 BUD22 PF09073.10 KFX95491.1 - 0.0018 17.7 24.8 0.0034 16.8 24.8 1.4 1 0 0 1 1 1 1 BUD22 Pkinase_Tyr PF07714.17 KFX95491.1 - 0.0026 17.1 0.1 0.012 14.9 0.1 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KFX95491.1 - 0.0083 16.1 3.1 0.011 15.7 0.1 2.3 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 KFX95491.1 - 0.029 13.7 0.0 0.067 12.5 0.0 1.6 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Mad3_BUB1_I_2 PF17014.5 KFX95491.1 - 0.13 12.4 0.0 0.39 10.9 0.0 1.8 2 0 0 2 2 2 0 Putative Mad3/BUB1 like region 1 protein Indigoidine_A PF04227.12 KFX95492.1 - 3.3e-121 404.1 0.4 5.9e-121 403.3 0.4 1.4 1 0 0 1 1 1 1 Indigoidine synthase A like protein PfkB PF00294.24 KFX95492.1 - 2.5e-15 56.5 5.1 1.5e-08 34.4 0.1 2.7 3 0 0 3 3 3 2 pfkB family carbohydrate kinase RabGAP-TBC PF00566.18 KFX95512.1 - 3.2e-48 164.2 0.0 5.8e-48 163.4 0.0 1.5 1 0 0 1 1 1 1 Rab-GTPase-TBC domain PRP1_N PF06424.12 KFX95512.1 - 2.7 8.4 14.7 2.7 8.4 10.8 2.5 2 1 0 2 2 2 0 PRP1 splicing factor, N-terminal ATP-synt_E PF05680.12 KFX95515.1 - 0.06 13.7 0.9 0.06 13.7 0.9 2.6 3 0 0 3 3 3 0 ATP synthase E chain GTP_EFTU PF00009.27 KFX95516.1 - 2.7e-07 30.3 0.0 7.6e-07 28.9 0.0 1.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_16 PF13191.6 KFX95516.1 - 0.052 13.9 0.3 0.15 12.4 0.1 1.9 2 0 0 2 2 2 0 AAA ATPase domain HCV_NS4a PF01006.20 KFX95516.1 - 0.12 12.1 0.2 1 9.2 0.0 2.6 3 0 0 3 3 3 0 Hepatitis C virus non-structural protein NS4a Rab5ip PF07019.12 KFX95517.1 - 2.3e-27 95.4 7.8 2.7e-27 95.2 7.8 1.1 1 0 0 1 1 1 1 Rab5-interacting protein (Rab5ip) BCLP PF12304.8 KFX95517.1 - 0.029 13.9 0.9 1.1 8.8 0.1 2.1 2 0 0 2 2 2 0 Beta-casein like protein TMEM208_SND2 PF05620.11 KFX95517.1 - 0.17 11.6 0.5 0.2 11.4 0.5 1.1 1 0 0 1 1 1 0 SRP-independent targeting protein 2/TMEM208 Peptidase_U4 PF03419.13 KFX95517.1 - 0.8 8.9 3.9 0.89 8.8 3.9 1.0 1 0 0 1 1 1 0 Sporulation factor SpoIIGA Vezatin PF12632.7 KFX95519.1 - 4.9e-80 268.9 0.0 1.1e-79 267.8 0.0 1.5 1 0 0 1 1 1 1 Mysoin-binding motif of peroxisomes PCNA_N PF00705.18 KFX95519.1 - 1.4e-55 186.4 3.8 3.4e-55 185.2 3.8 1.6 1 0 0 1 1 1 1 Proliferating cell nuclear antigen, N-terminal domain PCNA_C PF02747.15 KFX95519.1 - 5.7e-48 162.3 0.0 1.4e-47 161.0 0.0 1.7 2 0 0 2 2 2 1 Proliferating cell nuclear antigen, C-terminal domain Rad9 PF04139.13 KFX95519.1 - 1.6e-07 31.0 0.0 2.8e-07 30.2 0.0 1.3 1 0 0 1 1 1 1 Rad9 Hus1 PF04005.12 KFX95519.1 - 0.0016 17.6 0.0 0.003 16.7 0.0 1.5 1 0 0 1 1 1 1 Hus1-like protein Rad1 PF02144.16 KFX95519.1 - 0.0024 17.0 0.6 0.054 12.5 0.6 2.2 1 1 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 DUF1480 PF07351.13 KFX95519.1 - 0.058 13.7 0.0 0.13 12.5 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1480) AMA-1 PF02430.15 KFX95519.1 - 0.11 11.4 2.3 1.2 8.0 0.0 2.8 3 0 0 3 3 3 0 Apical membrane antigen 1 Amastin PF07344.11 KFX95519.1 - 0.19 11.6 0.6 0.39 10.6 0.6 1.4 1 0 0 1 1 1 0 Amastin surface glycoprotein Phos_pyr_kin PF08543.12 KFX95520.1 - 1.7e-13 50.5 0.0 3.4e-13 49.6 0.0 1.6 1 1 0 1 1 1 1 Phosphomethylpyrimidine kinase PfkB PF00294.24 KFX95520.1 - 2.1e-06 27.3 0.1 1.4e-05 24.6 0.0 2.1 2 0 0 2 2 2 1 pfkB family carbohydrate kinase dUTPase PF00692.19 KFX95521.1 - 1.6e-44 150.7 0.0 2e-44 150.4 0.0 1.1 1 0 0 1 1 1 1 dUTPase DCD PF06559.11 KFX95521.1 - 0.049 12.4 0.0 0.068 11.9 0.0 1.1 1 0 0 1 1 1 0 2'-deoxycytidine 5'-triphosphate deaminase (DCD) MARVEL PF01284.23 KFX95522.1 - 4.3e-06 26.8 19.5 5.7e-06 26.4 19.5 1.2 1 0 0 1 1 1 1 Membrane-associating domain DUF2339 PF10101.9 KFX95522.1 - 0.0086 14.7 8.9 0.0098 14.5 8.9 1.1 1 0 0 1 1 1 1 Predicted membrane protein (DUF2339) Rit1_C PF17184.4 KFX95523.1 - 5.6e-108 360.5 0.0 7.7e-108 360.1 0.0 1.2 1 0 0 1 1 1 1 Rit1 N-terminal domain Init_tRNA_PT PF04179.12 KFX95523.1 - 3.5e-35 120.6 0.0 8.7e-35 119.4 0.0 1.7 1 0 0 1 1 1 1 Rit1 DUSP-like domain AF-4 PF05110.13 KFX95524.1 - 0.3 9.1 6.6 0.41 8.7 6.6 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein Serglycin PF04360.12 KFX95524.1 - 3 7.8 6.3 5.7 6.9 5.9 1.6 1 1 0 1 1 1 0 Serglycin Aldolase_II PF00596.21 KFX95525.1 - 6.8e-45 153.3 0.0 8e-45 153.1 0.0 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain Calreticulin PF00262.18 KFX95526.1 - 1e-167 557.6 17.8 1.5e-167 557.1 17.8 1.2 1 0 0 1 1 1 1 Calreticulin family Mito_carr PF00153.27 KFX95529.1 - 7.5e-20 70.7 0.2 8.2e-20 70.5 0.2 1.0 1 0 0 1 1 1 1 Mitochondrial carrier protein zf-H2C2 PF09337.10 KFX95541.1 - 2.8e-15 56.2 0.6 6.9e-15 55.0 0.6 1.7 1 0 0 1 1 1 1 H2C2 zinc finger Integrase_H2C2 PF17921.1 KFX95541.1 - 1.1e-11 44.7 0.4 2.3e-11 43.6 0.4 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain Acetyltransf_1 PF00583.25 KFX95541.1 - 0.00032 20.9 0.0 0.00068 19.8 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_3 PF13302.7 KFX95541.1 - 0.017 15.8 0.1 0.049 14.3 0.0 1.9 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain FR47 PF08445.10 KFX95541.1 - 0.048 13.6 0.0 0.12 12.4 0.0 1.6 1 0 0 1 1 1 0 FR47-like protein Acetyltransf_4 PF13420.7 KFX95541.1 - 0.058 13.5 0.0 0.11 12.7 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Cpn60_TCP1 PF00118.24 KFX95542.1 - 1.1e-154 515.8 4.8 1.3e-154 515.5 4.8 1.1 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family CSN8_PSD8_EIF3K PF10075.9 KFX95542.1 - 1.2e-41 142.1 0.0 2e-41 141.3 0.0 1.4 1 0 0 1 1 1 1 CSN8/PSMD8/EIF3K family HD PF01966.22 KFX95543.1 - 1.2e-08 35.2 0.1 1.7e-08 34.7 0.1 1.3 1 0 0 1 1 1 1 HD domain HD_4 PF13328.6 KFX95543.1 - 0.00016 21.4 0.1 0.00033 20.4 0.1 1.5 1 1 0 1 1 1 1 HD domain MIOX PF05153.15 KFX95543.1 - 0.012 15.2 0.0 0.017 14.7 0.0 1.2 1 0 0 1 1 1 0 Myo-inositol oxygenase HDOD PF08668.12 KFX95543.1 - 0.047 13.2 0.0 0.13 11.7 0.0 1.8 1 1 0 1 1 1 0 HDOD domain Hydrolase_6 PF13344.6 KFX95543.1 - 0.17 12.0 0.0 0.25 11.5 0.0 1.4 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase PhyH PF05721.13 KFX95544.1 - 1.1e-25 91.1 0.0 1.5e-25 90.7 0.0 1.2 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) 2OG-FeII_Oxy_5 PF13759.6 KFX95544.1 - 0.0018 18.7 0.0 0.0035 17.7 0.0 1.5 1 0 0 1 1 1 1 Putative 2OG-Fe(II) oxygenase 2OG-FeII_Oxy_3 PF13640.6 KFX95544.1 - 0.0024 18.7 0.0 0.0058 17.5 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Sugar_tr PF00083.24 KFX95545.1 - 2.3e-41 142.1 26.5 7.4e-39 133.9 26.5 2.2 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KFX95545.1 - 1e-32 113.5 52.3 9.9e-22 77.3 33.9 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Phage_holin_2_4 PF16082.5 KFX95545.1 - 0.055 13.2 1.5 0.093 12.5 0.0 2.2 2 0 0 2 2 2 0 Bacteriophage holin family, superfamily II-like DNA_ligase_A_M PF01068.21 KFX95546.1 - 5.3e-51 173.2 0.0 3.1e-48 164.1 0.0 2.2 2 0 0 2 2 2 2 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.14 KFX95546.1 - 1.3e-35 123.3 0.0 2.5e-35 122.3 0.0 1.5 1 0 0 1 1 1 1 DNA ligase N terminus DNA_ligase_A_C PF04679.15 KFX95546.1 - 1.6e-17 63.9 0.0 6.9e-17 61.9 0.0 2.1 1 0 0 1 1 1 1 ATP dependent DNA ligase C terminal region RNA_ligase PF09414.10 KFX95546.1 - 5.5e-05 23.5 0.0 0.0001 22.6 0.0 1.4 1 0 0 1 1 1 1 RNA ligase KH_2 PF07650.17 KFX95546.1 - 0.14 12.0 0.2 0.39 10.6 0.2 1.7 1 0 0 1 1 1 0 KH domain GAGA_bind PF06217.12 KFX95546.1 - 5.5 7.2 5.4 57 3.8 0.0 3.0 3 0 0 3 3 3 0 GAGA binding protein-like family RINT1_TIP1 PF04437.13 KFX95547.1 - 7.9e-166 552.8 0.5 1.8e-165 551.6 0.0 1.7 2 0 0 2 2 2 1 RINT-1 / TIP-1 family Herpes_U30 PF04523.13 KFX95547.1 - 0.0099 13.8 0.6 0.014 13.3 0.6 1.1 1 0 0 1 1 1 1 Herpes virus tegument protein U30 Fez1 PF06818.15 KFX95547.1 - 0.038 14.4 1.2 0.077 13.4 1.2 1.5 1 0 0 1 1 1 0 Fez1 Sec34 PF04136.15 KFX95547.1 - 0.052 13.4 1.6 0.24 11.3 1.5 2.1 2 0 0 2 2 2 0 Sec34-like family DUF4164 PF13747.6 KFX95547.1 - 0.44 10.9 4.8 2.8 8.3 3.5 2.8 2 1 0 2 2 2 0 Domain of unknown function (DUF4164) DUF908 PF06012.12 KFX95548.1 - 0.12 11.7 2.9 0.17 11.2 2.9 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) SR-25 PF10500.9 KFX95548.1 - 0.41 10.2 11.0 0.59 9.7 11.0 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein ketoacyl-synt PF00109.26 KFX95549.1 - 1.1e-80 270.8 0.0 2.1e-80 269.9 0.0 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 KFX95549.1 - 2e-36 124.6 0.0 6.3e-36 123.0 0.0 1.9 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Acyl_transf_1 PF00698.21 KFX95549.1 - 1.1e-26 94.2 0.1 1.6e-26 93.6 0.1 1.2 1 0 0 1 1 1 1 Acyl transferase domain KAsynt_C_assoc PF16197.5 KFX95549.1 - 4.3e-16 59.4 0.0 1.1e-14 54.8 0.0 2.3 1 1 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension Thiolase_N PF00108.23 KFX95549.1 - 4.1e-05 23.1 0.1 8.8e-05 22.0 0.1 1.5 1 0 0 1 1 1 1 Thiolase, N-terminal domain RF-1 PF00472.20 KFX95569.1 - 6.9e-23 80.8 0.6 1e-22 80.3 0.6 1.2 1 0 0 1 1 1 1 RF-1 domain Cwf_Cwc_15 PF04889.12 KFX95569.1 - 0.023 14.4 1.1 0.028 14.2 1.1 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Thioredoxin_15 PF18403.1 KFX95569.1 - 0.056 13.4 0.2 0.074 13.0 0.2 1.1 1 0 0 1 1 1 0 Thioredoxin-like domain GCS PF03074.16 KFX95571.1 - 3.4e-172 572.9 0.0 4.1e-172 572.6 0.0 1.1 1 0 0 1 1 1 1 Glutamate-cysteine ligase ADH_zinc_N PF00107.26 KFX95576.1 - 3e-26 91.9 1.0 3e-26 91.9 1.0 1.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KFX95576.1 - 3e-14 54.2 0.0 7.1e-14 53.0 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KFX95576.1 - 1.3e-09 37.9 0.0 3.7e-09 36.4 0.0 1.8 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain TrkA_N PF02254.18 KFX95576.1 - 0.00024 21.4 0.0 0.00044 20.5 0.0 1.4 1 0 0 1 1 1 1 TrkA-N domain AlaDh_PNT_C PF01262.21 KFX95576.1 - 0.048 13.0 0.7 0.075 12.3 0.7 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Glyco_hydro_61 PF03443.14 KFX95577.1 - 1.6e-54 185.0 0.0 1.9e-54 184.7 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 COA2 PF17051.5 KFX95578.1 - 2e-05 24.5 0.0 2.7e-05 24.1 0.0 1.2 1 0 0 1 1 1 1 Cytochrome C oxidase assembly factor 2 Metallophos PF00149.28 KFX95579.1 - 1.8e-31 110.2 0.0 5.1e-22 79.4 0.0 2.2 1 1 0 2 2 2 2 Calcineurin-like phosphoesterase STPPase_N PF16891.5 KFX95579.1 - 0.15 12.5 0.1 0.38 11.2 0.1 1.7 1 0 0 1 1 1 0 Serine-threonine protein phosphatase N-terminal domain Pyridox_oxase_2 PF12766.7 KFX95581.1 - 3.5e-21 75.7 0.0 6.3e-21 74.9 0.0 1.4 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Fungal_trans PF04082.18 KFX95582.1 - 7.5e-44 149.8 0.1 2.6e-43 148.0 0.0 1.8 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KFX95582.1 - 1.3e-08 34.8 8.1 2.7e-08 33.8 8.1 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain eIF3m_C_helix PF18005.1 KFX95582.1 - 0.16 11.7 0.5 0.37 10.5 0.5 1.6 1 0 0 1 1 1 0 eIF3 subunit M, C-terminal helix Cellulase PF00150.18 KFX95583.1 - 1.1e-28 100.5 0.8 1.6e-28 99.9 0.8 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Nipped-B_C PF12830.7 KFX95584.1 - 1.3e-48 165.5 10.8 8.4e-48 162.8 3.3 3.3 3 0 0 3 3 3 2 Sister chromatid cohesion C-terminus Cohesin_HEAT PF12765.7 KFX95584.1 - 3e-05 24.2 1.2 7.7e-05 22.9 0.2 2.3 2 0 0 2 2 2 1 HEAT repeat associated with sister chromatid cohesion Cnd1 PF12717.7 KFX95584.1 - 0.00023 21.2 1.2 0.0014 18.7 0.4 2.8 1 1 1 2 2 2 2 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 KFX95584.1 - 0.027 14.7 7.5 19 5.8 0.0 5.9 5 0 0 5 5 5 0 HEAT repeat HEAT_2 PF13646.6 KFX95584.1 - 0.027 14.8 3.0 1 9.8 1.6 4.2 2 1 1 3 3 3 0 HEAT repeats AAA_lid_7 PF17867.1 KFX95584.1 - 0.08 13.2 0.1 0.47 10.7 0.1 2.4 1 0 0 1 1 1 0 Midasin AAA lid domain Exo70 PF03081.15 KFX95584.1 - 0.12 11.5 2.1 0.35 9.9 1.1 2.3 3 0 0 3 3 3 0 Exo70 exocyst complex subunit TFIIS_C PF01096.18 KFX95585.1 - 3.4e-14 52.4 1.9 3.4e-14 52.4 1.9 3.2 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.16 KFX95585.1 - 3.2e-05 23.7 2.1 3.2e-05 23.7 2.1 2.7 3 0 0 3 3 3 1 RNA polymerases M/15 Kd subunit zinc_ribbon_2 PF13240.6 KFX95585.1 - 0.0026 17.4 11.8 1.9 8.3 0.1 4.0 4 0 0 4 4 4 3 zinc-ribbon domain zf-RING_7 PF02591.15 KFX95585.1 - 0.013 15.7 5.7 0.21 11.8 0.1 3.4 3 0 0 3 3 3 0 C4-type zinc ribbon domain RecR PF02132.15 KFX95585.1 - 0.028 14.0 2.1 0.028 14.0 2.1 2.2 2 0 0 2 2 2 0 RecR protein GcpE PF04551.14 KFX95585.1 - 0.086 11.9 0.4 0.11 11.6 0.4 1.3 1 1 0 1 1 1 0 GcpE protein DUF3797 PF12677.7 KFX95585.1 - 0.15 11.9 0.2 0.15 11.9 0.2 2.6 3 0 0 3 3 2 0 Domain of unknown function (DUF3797) OrfB_Zn_ribbon PF07282.11 KFX95585.1 - 0.17 11.9 12.2 0.44 10.5 0.8 3.0 2 1 1 3 3 3 0 Putative transposase DNA-binding domain Zn-ribbon_8 PF09723.10 KFX95585.1 - 0.34 11.1 0.1 0.34 11.1 0.1 3.0 3 0 0 3 3 3 0 Zinc ribbon domain UPF0547 PF10571.9 KFX95585.1 - 0.58 10.3 17.4 0.71 10.0 0.3 4.0 4 0 0 4 4 4 0 Uncharacterised protein family UPF0547 Ribosomal_S27e PF01667.17 KFX95585.1 - 0.82 9.4 7.3 31 4.4 0.1 3.2 2 1 0 2 2 2 0 Ribosomal protein S27 DZR PF12773.7 KFX95585.1 - 1.1 9.4 14.3 1.5 9.0 3.3 2.8 1 1 2 3 3 3 0 Double zinc ribbon zf-ribbon_3 PF13248.6 KFX95585.1 - 1.1 8.8 12.6 1 8.9 0.1 3.8 4 0 0 4 4 4 0 zinc-ribbon domain Nudix_N_2 PF14803.6 KFX95585.1 - 1.4 8.9 11.2 1.2 9.1 2.7 3.1 3 0 0 3 3 3 0 Nudix N-terminal TF_Zn_Ribbon PF08271.12 KFX95585.1 - 1.5 8.4 15.9 0.87 9.2 1.0 3.5 2 2 0 2 2 2 0 TFIIB zinc-binding DUF2072 PF09845.9 KFX95585.1 - 1.8 8.8 7.8 7.5 6.8 0.3 2.2 1 1 1 2 2 2 0 Zn-ribbon containing protein zf-IS66 PF13005.7 KFX95585.1 - 1.8 9.0 12.6 13 6.2 0.1 3.8 4 0 0 4 4 4 0 zinc-finger binding domain of transposase IS66 Lar_restr_allev PF14354.6 KFX95585.1 - 5.8 7.4 11.9 7.5 7.0 1.5 3.1 2 2 0 2 2 2 0 Restriction alleviation protein Lar HEAT_2 PF13646.6 KFX95586.1 - 2.7e-26 91.8 9.3 1.1e-13 51.4 0.2 3.2 2 2 2 4 4 4 2 HEAT repeats HEAT_PBS PF03130.16 KFX95586.1 - 4.3e-19 67.2 7.0 0.00091 19.7 0.2 6.6 6 0 0 6 6 6 5 PBS lyase HEAT-like repeat HEAT PF02985.22 KFX95586.1 - 5.4e-07 29.3 4.1 0.11 12.8 0.0 5.8 6 0 0 6 6 6 2 HEAT repeat HEAT_EZ PF13513.6 KFX95586.1 - 0.00043 20.7 8.0 0.37 11.4 0.1 4.9 4 1 1 5 5 5 2 HEAT-like repeat Cohesin_HEAT PF12765.7 KFX95586.1 - 0.083 13.2 0.3 0.68 10.3 0.0 2.5 3 0 0 3 3 3 0 HEAT repeat associated with sister chromatid cohesion ERAP1_C PF11838.8 KFX95586.1 - 0.089 12.3 1.0 4 6.9 0.0 2.3 2 0 0 2 2 2 0 ERAP1-like C-terminal domain Cnd1 PF12717.7 KFX95586.1 - 0.16 12.0 0.0 1.6 8.7 0.0 2.5 2 1 1 3 3 3 0 non-SMC mitotic condensation complex subunit 1 ABC_tran PF00005.27 KFX95587.1 - 1.6e-47 161.5 0.1 3.5e-23 82.7 0.0 3.8 2 2 0 2 2 2 2 ABC transporter 4HB PF17947.1 KFX95587.1 - 1.5e-29 101.9 1.3 3.6e-29 100.6 0.2 2.4 2 0 0 2 2 1 1 Four helical bundle domain SMC_N PF02463.19 KFX95587.1 - 4.3e-18 65.6 0.0 1.6e-06 27.7 0.2 3.8 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 KFX95587.1 - 3.4e-17 63.2 0.2 0.0021 18.0 0.0 4.9 4 1 1 5 5 5 4 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 KFX95587.1 - 2.5e-10 41.2 4.8 0.0001 22.9 0.0 3.4 4 0 0 4 4 3 2 AAA domain AAA_29 PF13555.6 KFX95587.1 - 1.4e-08 34.3 0.1 0.0047 16.6 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 KFX95587.1 - 2.8e-08 33.9 0.0 0.00037 20.5 0.0 2.9 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 KFX95587.1 - 1.7e-07 31.3 0.0 0.0014 18.7 0.0 2.9 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_22 PF13401.6 KFX95587.1 - 3.6e-07 30.6 0.1 0.0052 17.1 0.0 3.5 4 0 0 4 4 2 2 AAA domain Dynamin_N PF00350.23 KFX95587.1 - 5.3e-07 29.9 0.1 0.00032 20.8 0.0 3.1 3 0 0 3 3 3 1 Dynamin family AAA_28 PF13521.6 KFX95587.1 - 6.8e-07 29.7 0.1 0.016 15.4 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.6 KFX95587.1 - 5e-06 27.1 0.1 0.098 13.2 0.1 3.0 2 0 0 2 2 2 2 AAA domain AAA_33 PF13671.6 KFX95587.1 - 1.8e-05 24.9 0.1 0.43 10.7 0.0 3.4 3 0 0 3 3 3 2 AAA domain RNA_helicase PF00910.22 KFX95587.1 - 5.9e-05 23.4 0.0 0.84 10.1 0.0 2.9 2 0 0 2 2 2 2 RNA helicase AAA PF00004.29 KFX95587.1 - 7.5e-05 23.2 0.0 0.43 11.0 0.0 4.0 4 0 0 4 4 3 1 ATPase family associated with various cellular activities (AAA) MeaB PF03308.16 KFX95587.1 - 9.9e-05 21.4 0.1 0.36 9.8 0.0 2.6 2 0 0 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_15 PF13175.6 KFX95587.1 - 0.00013 21.8 5.7 0.037 13.7 0.1 3.8 4 1 0 5 5 4 2 AAA ATPase domain AAA_16 PF13191.6 KFX95587.1 - 0.00014 22.3 1.2 0.56 10.6 0.0 3.6 5 0 0 5 5 2 2 AAA ATPase domain AAA_27 PF13514.6 KFX95587.1 - 0.00018 21.1 0.0 0.15 11.7 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_24 PF13479.6 KFX95587.1 - 0.00068 19.4 0.1 1.4 8.6 0.0 3.0 3 0 0 3 3 2 2 AAA domain NACHT PF05729.12 KFX95587.1 - 0.00074 19.5 0.1 0.18 11.7 0.0 2.6 2 0 0 2 2 2 1 NACHT domain PduV-EutP PF10662.9 KFX95587.1 - 0.00075 19.3 0.0 0.66 9.7 0.0 3.0 3 0 0 3 3 2 1 Ethanolamine utilisation - propanediol utilisation AAA_30 PF13604.6 KFX95587.1 - 0.00095 18.9 0.0 2.5 7.8 0.0 3.3 3 0 0 3 3 3 1 AAA domain Rad17 PF03215.15 KFX95587.1 - 0.0014 18.6 0.0 1.5 8.7 0.0 2.5 2 0 0 2 2 2 1 Rad17 P-loop domain AAA_14 PF13173.6 KFX95587.1 - 0.0015 18.6 0.0 2.4 8.2 0.0 3.2 3 0 0 3 3 3 1 AAA domain G-alpha PF00503.20 KFX95587.1 - 0.0026 17.0 0.1 2 7.5 0.0 2.8 3 0 0 3 3 3 1 G-protein alpha subunit DUF87 PF01935.17 KFX95587.1 - 0.0027 17.9 1.9 1.1 9.3 0.1 3.6 3 0 0 3 3 3 1 Helicase HerA, central domain cobW PF02492.19 KFX95587.1 - 0.0038 16.8 0.2 2.7 7.6 0.0 3.2 4 0 0 4 4 2 1 CobW/HypB/UreG, nucleotide-binding domain Roc PF08477.13 KFX95587.1 - 0.0058 16.8 0.2 9.7 6.4 0.0 3.4 3 0 0 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase ATPase_2 PF01637.18 KFX95587.1 - 0.0085 16.0 0.0 2.4 8.0 0.0 3.3 3 0 0 3 3 2 1 ATPase domain predominantly from Archaea ATP_bind_1 PF03029.17 KFX95587.1 - 0.017 14.9 0.2 7.7 6.2 0.0 2.7 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein CLP1_P PF16575.5 KFX95587.1 - 0.019 14.8 0.0 0.86 9.4 0.0 2.7 2 0 0 2 2 2 0 mRNA cleavage and polyadenylation factor CLP1 P-loop NB-ARC PF00931.22 KFX95587.1 - 0.019 14.1 1.9 0.32 10.1 0.0 2.6 3 0 0 3 3 2 0 NB-ARC domain IstB_IS21 PF01695.17 KFX95587.1 - 0.019 14.7 0.0 4.9 6.8 0.0 3.0 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_7 PF12775.7 KFX95587.1 - 0.019 14.5 0.0 3.2 7.2 0.0 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region SbcCD_C PF13558.6 KFX95587.1 - 0.022 15.0 0.0 5.5 7.3 0.0 3.0 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit PRK PF00485.18 KFX95587.1 - 0.032 14.0 0.0 1.2 8.9 0.0 2.4 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family ATP-synt_ab PF00006.25 KFX95587.1 - 0.036 13.7 0.0 12 5.5 0.0 2.5 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain Septin PF00735.18 KFX95587.1 - 0.039 13.2 0.1 5.3 6.2 0.0 2.7 2 0 0 2 2 2 0 Septin Mg_chelatase PF01078.21 KFX95587.1 - 0.04 13.3 0.1 4 6.8 0.0 3.0 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI NTPase_1 PF03266.15 KFX95587.1 - 0.044 13.7 0.1 10 6.0 0.1 2.8 2 0 0 2 2 2 0 NTPase Cytidylate_kin PF02224.18 KFX95587.1 - 0.049 13.4 0.0 13 5.5 0.0 2.7 2 0 0 2 2 2 0 Cytidylate kinase MukB PF04310.12 KFX95587.1 - 0.061 13.1 0.2 12 5.6 0.0 2.4 2 0 0 2 2 2 0 MukB N-terminal AAA_25 PF13481.6 KFX95587.1 - 0.062 12.9 0.0 13 5.3 0.0 3.0 2 0 0 2 2 2 0 AAA domain HEAT PF02985.22 KFX95587.1 - 0.089 13.1 0.1 31 5.2 0.0 3.8 3 0 0 3 3 2 0 HEAT repeat T2SSE PF00437.20 KFX95587.1 - 0.12 11.4 1.7 7.8 5.5 0.0 3.2 3 0 0 3 3 3 0 Type II/IV secretion system protein FeoB_N PF02421.18 KFX95587.1 - 0.13 11.8 0.2 1 8.8 0.1 2.2 2 0 0 2 2 2 0 Ferrous iron transport protein B TsaE PF02367.17 KFX95587.1 - 0.14 12.1 0.2 26 4.8 0.0 2.9 3 0 0 3 3 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_13 PF13166.6 KFX95587.1 - 0.9 8.1 11.3 1.6 7.3 0.0 4.3 5 0 0 5 5 4 0 AAA domain DAP3 PF10236.9 KFX95587.1 - 2.3 7.3 5.9 13 4.9 1.2 2.9 3 0 0 3 3 3 0 Mitochondrial ribosomal death-associated protein 3 V-ATPase_H_C PF11698.8 KFX95587.1 - 3.1 8.0 4.8 1.9 8.6 1.8 2.2 2 0 0 2 2 1 0 V-ATPase subunit H Methyltr_RsmB-F PF01189.17 KFX95603.1 - 9.4e-32 110.3 0.0 4.3e-25 88.6 0.0 3.1 3 1 0 3 3 3 2 16S rRNA methyltransferase RsmB/F F-box PF00646.33 KFX95603.1 - 6.8e-06 25.8 0.0 1.5e-05 24.8 0.0 1.6 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 KFX95603.1 - 1.3e-05 25.0 0.0 3.3e-05 23.7 0.0 1.8 1 0 0 1 1 1 1 F-box-like F-box-like_2 PF13013.6 KFX95603.1 - 0.023 14.6 0.0 0.095 12.7 0.0 2.0 2 0 0 2 2 2 0 F-box-like domain Transglut_core PF01841.19 KFX95604.1 - 2.7e-11 43.9 0.0 5.2e-11 43.0 0.0 1.4 1 0 0 1 1 1 1 Transglutaminase-like superfamily DUF553 PF04473.12 KFX95604.1 - 0.00079 19.0 0.0 0.018 14.6 0.0 2.6 2 1 1 3 3 3 1 Transglutaminase-like domain Hemerythrin PF01814.23 KFX95605.1 - 2.8e-08 34.5 0.9 1e-07 32.7 0.9 1.9 1 1 0 1 1 1 1 Hemerythrin HHE cation binding domain Aldolase_II PF00596.21 KFX95606.1 - 3.8e-45 154.1 0.0 5.6e-45 153.6 0.0 1.2 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain SET PF00856.28 KFX95610.1 - 0.00021 21.7 0.0 0.00055 20.4 0.0 1.6 1 1 0 1 1 1 1 SET domain F-box-like PF12937.7 KFX95611.1 - 1.5e-07 31.2 1.1 4e-07 29.8 1.1 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KFX95611.1 - 0.0014 18.4 0.1 0.006 16.4 0.1 2.1 1 0 0 1 1 1 1 F-box domain F-box_4 PF15966.5 KFX95611.1 - 0.23 11.4 0.9 0.72 9.7 0.4 2.0 2 0 0 2 2 2 0 F-box COesterase PF00135.28 KFX95612.1 - 2.3e-79 267.6 0.0 3.1e-79 267.2 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KFX95612.1 - 5.7e-06 26.3 0.2 1.6e-05 24.9 0.2 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 KFX95612.1 - 0.14 11.0 0.2 0.33 9.7 0.0 1.6 2 0 0 2 2 2 0 Steryl acetyl hydrolase Peptidase_S9 PF00326.21 KFX95612.1 - 0.19 11.1 0.3 0.44 10.0 0.3 1.5 1 0 0 1 1 1 0 Prolyl oligopeptidase family DUF824 PF05688.11 KFX95612.1 - 0.31 10.9 3.5 0.54 10.1 0.7 2.4 2 0 0 2 2 2 0 Salmonella repeat of unknown function (DUF824) Aconitase PF00330.20 KFX95613.1 - 7.7e-108 361.4 0.2 5.7e-107 358.6 0.2 2.0 1 1 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 KFX95613.1 - 3.4e-24 85.7 0.0 6.1e-24 84.8 0.0 1.4 1 0 0 1 1 1 1 Aconitase C-terminal domain MCM PF00493.23 KFX95613.1 - 0.092 11.8 0.1 0.17 10.9 0.1 1.3 1 0 0 1 1 1 0 MCM P-loop domain Erf4 PF10256.9 KFX95615.1 - 1.3e-09 38.1 0.0 1.6e-09 37.9 0.0 1.1 1 0 0 1 1 1 1 Golgin subfamily A member 7/ERF4 family Thioredox_DsbH PF03190.15 KFX95617.1 - 3.8e-68 228.5 0.0 6.1e-68 227.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF255 Thioredoxin_7 PF13899.6 KFX95617.1 - 1.2e-08 35.0 0.0 2.4e-08 34.1 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_2 PF13098.6 KFX95617.1 - 0.13 12.7 0.0 0.28 11.7 0.0 1.5 1 0 0 1 1 1 0 Thioredoxin-like domain HTH_10 PF04967.12 KFX95617.1 - 0.16 11.8 0.1 0.36 10.7 0.1 1.6 1 0 0 1 1 1 0 HTH DNA binding domain DUF2406 PF10295.9 KFX95621.1 - 1.5e-27 96.0 0.5 1.5e-27 96.0 0.5 2.1 2 0 0 2 2 2 1 Uncharacterised protein (DUF2406) VMA21 PF09446.10 KFX95622.1 - 1.9e-14 53.5 11.6 3.4e-14 52.7 11.6 1.4 1 0 0 1 1 1 1 VMA21-like domain SNF2_N PF00176.23 KFX95623.1 - 2.3e-47 161.4 0.0 3.7e-47 160.7 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KFX95623.1 - 4.3e-16 59.2 0.1 2.9e-15 56.6 0.1 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KFX95623.1 - 5.2e-08 33.1 0.0 1.7e-07 31.4 0.0 1.9 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 KFX95623.1 - 3.5e-07 29.7 0.0 6.4e-07 28.8 0.0 1.3 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase TK PF00265.18 KFX95623.1 - 0.1 12.5 0.0 0.25 11.2 0.0 1.6 1 0 0 1 1 1 0 Thymidine kinase G6PD_C PF02781.16 KFX95641.1 - 4.3e-115 383.9 0.0 1.1e-114 382.6 0.0 1.5 2 0 0 2 2 2 1 Glucose-6-phosphate dehydrogenase, C-terminal domain G6PD_N PF00479.22 KFX95641.1 - 1.3e-62 211.5 0.2 2.4e-62 210.7 0.2 1.4 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, NAD binding domain DUF3226 PF11536.8 KFX95641.1 - 0.008 15.9 0.1 0.016 14.9 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3226) ArAE_1_C PF11728.8 KFX95641.1 - 0.016 15.2 0.4 0.034 14.1 0.4 1.5 1 0 0 1 1 1 0 Putative aromatic acid exporter C-terminal domain Ribosomal_L35Ae PF01247.18 KFX95642.1 - 4e-43 145.5 0.3 4.6e-43 145.3 0.3 1.0 1 0 0 1 1 1 1 Ribosomal protein L35Ae RimM PF01782.18 KFX95642.1 - 0.007 16.6 0.0 2.2 8.6 0.0 2.2 2 0 0 2 2 2 2 RimM N-terminal domain PGAP1 PF07819.13 KFX95661.1 - 0.001 18.9 0.1 0.0015 18.3 0.1 1.2 1 0 0 1 1 1 1 PGAP1-like protein Hydrolase_4 PF12146.8 KFX95661.1 - 0.005 16.1 0.0 0.0074 15.6 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KFX95661.1 - 0.0082 16.8 7.1 0.0082 16.8 7.1 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF676 PF05057.14 KFX95661.1 - 0.13 11.7 0.0 0.19 11.2 0.0 1.2 1 0 0 1 1 1 0 Putative serine esterase (DUF676) DUF521 PF04412.13 KFX95662.1 - 0.0087 14.8 0.0 0.0087 14.8 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF521) DUF2197 PF09963.9 KFX95662.1 - 0.062 13.6 0.0 0.12 12.7 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2197) Zincin_1 PF06262.11 KFX95663.1 - 0.11 12.6 0.1 0.25 11.5 0.1 1.5 1 0 0 1 1 1 0 Zincin-like metallopeptidase DUF4396 PF14342.6 KFX95664.1 - 3.1e-30 105.4 0.3 3.4e-30 105.2 0.3 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4396) PRP1_N PF06424.12 KFX95665.1 - 5.7e-52 176.1 7.3 1.3e-51 174.9 7.3 1.6 1 0 0 1 1 1 1 PRP1 splicing factor, N-terminal TPR_14 PF13428.6 KFX95665.1 - 1.7e-31 106.2 21.2 0.00017 22.1 0.0 12.6 4 3 8 12 12 12 9 Tetratricopeptide repeat TPR_19 PF14559.6 KFX95665.1 - 3.2e-26 91.6 14.3 9.2e-08 32.5 0.2 9.9 5 3 5 10 10 10 7 Tetratricopeptide repeat TPR_16 PF13432.6 KFX95665.1 - 2.1e-12 47.5 11.7 0.00032 21.3 0.0 7.0 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_2 PF07719.17 KFX95665.1 - 1.4e-11 43.6 11.6 0.25 11.5 0.0 9.6 12 0 0 12 12 9 3 Tetratricopeptide repeat TPR_8 PF13181.6 KFX95665.1 - 5e-10 38.8 0.0 0.71 10.2 0.0 7.5 9 0 0 9 9 8 2 Tetratricopeptide repeat TPR_17 PF13431.6 KFX95665.1 - 1.1e-08 34.9 2.0 30 5.3 0.2 9.1 9 1 1 10 10 9 0 Tetratricopeptide repeat TPR_1 PF00515.28 KFX95665.1 - 5.1e-07 29.2 0.1 0.67 9.9 0.0 5.1 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_15 PF13429.6 KFX95665.1 - 6.7e-07 28.8 18.9 6.5e-05 22.3 4.7 5.9 2 2 2 5 5 5 2 Tetratricopeptide repeat TPR_21 PF09976.9 KFX95665.1 - 2.5e-06 27.3 9.6 0.0094 15.7 1.0 4.7 3 1 0 4 4 4 2 Tetratricopeptide repeat-like domain TPR_6 PF13174.6 KFX95665.1 - 1.6e-05 25.2 6.6 27 5.7 0.0 8.7 9 0 0 9 9 9 0 Tetratricopeptide repeat TPR_11 PF13414.6 KFX95665.1 - 2.5e-05 23.9 5.2 3 7.6 0.0 6.2 5 1 1 6 6 6 1 TPR repeat TPR_9 PF13371.6 KFX95665.1 - 2.8e-05 24.2 7.6 0.35 11.0 0.1 5.2 5 1 0 6 6 5 2 Tetratricopeptide repeat NARP1 PF12569.8 KFX95665.1 - 0.0012 17.9 12.2 0.022 13.7 0.0 5.2 4 1 2 7 7 7 2 NMDA receptor-regulated protein 1 Suf PF05843.14 KFX95665.1 - 0.0012 18.9 1.8 4.5 7.2 0.0 4.3 5 2 1 6 6 6 2 Suppressor of forked protein (Suf) DUF3808 PF10300.9 KFX95665.1 - 0.0016 17.3 0.5 2.2 6.9 0.0 3.3 4 0 0 4 4 4 2 Protein of unknown function (DUF3808) TPR_12 PF13424.6 KFX95665.1 - 0.0027 17.9 4.3 1.8 8.9 0.1 5.8 5 2 0 5 5 5 1 Tetratricopeptide repeat Wzy_C_2 PF11846.8 KFX95665.1 - 0.013 15.5 2.7 4.6 7.1 0.1 3.8 2 1 2 4 4 4 0 Virulence factor membrane-bound polymerase, C-terminal ANAPC3 PF12895.7 KFX95665.1 - 0.013 15.7 0.2 5.2 7.4 0.0 4.0 3 1 1 4 4 3 0 Anaphase-promoting complex, cyclosome, subunit 3 ZNRF_3_ecto PF18212.1 KFX95665.1 - 0.063 13.3 0.3 58 3.8 0.0 4.2 4 0 0 4 4 4 0 ZNRF-3 Ectodomain RrnaAD PF00398.20 KFX95666.1 - 1.6e-62 211.0 0.0 2.1e-62 210.6 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_25 PF13649.6 KFX95666.1 - 2.1e-07 31.5 0.0 4.4e-07 30.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KFX95666.1 - 3.1e-05 24.5 0.0 7.3e-05 23.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 KFX95666.1 - 0.00013 21.8 0.0 0.00018 21.3 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) CMAS PF02353.20 KFX95666.1 - 0.00025 20.4 0.0 0.00037 19.9 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Met_10 PF02475.16 KFX95666.1 - 0.0018 18.1 0.1 0.0027 17.5 0.1 1.2 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_23 PF13489.6 KFX95666.1 - 0.0065 16.3 0.0 0.01 15.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.18 KFX95666.1 - 0.0082 15.5 0.0 0.013 14.8 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase domain Methyltransf_12 PF08242.12 KFX95666.1 - 0.0094 16.7 0.0 0.027 15.2 0.0 1.8 2 0 0 2 2 1 1 Methyltransferase domain MTS PF05175.14 KFX95666.1 - 0.01 15.4 0.0 0.017 14.7 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_31 PF13847.6 KFX95666.1 - 0.014 15.2 0.0 0.022 14.6 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain AAA_lid_4 PF17864.1 KFX95666.1 - 0.048 13.4 0.1 0.1 12.4 0.1 1.4 1 0 0 1 1 1 0 RuvB AAA lid domain Ubie_methyltran PF01209.18 KFX95666.1 - 0.15 11.4 0.0 0.22 10.8 0.0 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_18 PF12847.7 KFX95666.1 - 0.2 11.6 0.0 0.35 10.8 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain adh_short PF00106.25 KFX95667.1 - 8e-31 107.0 0.1 1e-30 106.6 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KFX95667.1 - 2.6e-23 82.8 0.0 3.1e-23 82.6 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KFX95667.1 - 2.1e-10 40.8 0.3 2.7e-10 40.4 0.3 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 KFX95667.1 - 0.00095 19.1 0.2 0.0015 18.4 0.2 1.4 1 1 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KFX95667.1 - 0.0021 17.6 0.0 0.0031 17.0 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KFX95667.1 - 0.02 13.9 0.2 0.026 13.5 0.2 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family DUF3426 PF11906.8 KFX95667.1 - 0.1 12.8 0.1 0.17 12.1 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3426) Dimer_Tnp_hAT PF05699.14 KFX95668.1 - 2.6e-21 75.2 0.0 5.6e-21 74.1 0.0 1.6 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region DUF4413 PF14372.6 KFX95668.1 - 0.00058 20.2 1.7 0.001 19.4 0.6 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4413) Octopine_DH PF02317.17 KFX95668.1 - 0.064 13.3 0.3 0.18 11.9 0.1 1.8 1 1 1 2 2 2 0 NAD/NADP octopine/nopaline dehydrogenase, alpha-helical domain Phosphoesterase PF04185.14 KFX95674.1 - 2.4e-62 211.2 2.0 3.1e-62 210.8 2.0 1.1 1 0 0 1 1 1 1 Phosphoesterase family VIT1 PF01988.19 KFX95675.1 - 1.2e-61 208.3 3.8 1.5e-61 208.1 3.8 1.1 1 0 0 1 1 1 1 VIT family K_oxygenase PF13434.6 KFX95676.1 - 2.2e-15 56.7 0.0 4.4e-11 42.5 0.0 2.1 2 0 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.6 KFX95676.1 - 7.6e-15 54.9 0.0 2.3e-14 53.4 0.0 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 KFX95676.1 - 9.7e-11 40.8 0.0 1.3e-10 40.4 0.0 1.1 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 KFX95676.1 - 2.6e-09 36.7 0.0 6.3e-09 35.5 0.0 1.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KFX95676.1 - 0.00028 21.0 0.0 0.00065 19.9 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 KFX95676.1 - 0.0005 19.4 0.0 0.0012 18.2 0.0 1.6 1 0 0 1 1 1 1 Thi4 family Lycopene_cycl PF05834.12 KFX95676.1 - 0.0079 15.3 0.0 0.012 14.7 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox PF00070.27 KFX95676.1 - 0.017 15.7 0.0 2.5 8.7 0.0 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KFX95676.1 - 0.023 14.7 0.0 0.045 13.7 0.0 1.6 1 1 0 1 1 1 0 FAD-NAD(P)-binding HI0933_like PF03486.14 KFX95676.1 - 0.086 11.5 0.0 3 6.4 0.0 2.1 2 0 0 2 2 2 0 HI0933-like protein DAO PF01266.24 KFX95676.1 - 0.096 12.2 0.1 2.6 7.6 0.0 2.1 2 0 0 2 2 2 0 FAD dependent oxidoreductase NAD_Gly3P_dh_N PF01210.23 KFX95676.1 - 0.16 11.9 0.0 0.46 10.5 0.0 1.7 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus GIY-YIG PF01541.24 KFX95678.1 - 1.8e-07 31.3 0.0 3.4e-07 30.5 0.0 1.4 1 0 0 1 1 1 1 GIY-YIG catalytic domain zf-HC5HC2H PF13771.6 KFX95678.1 - 0.0013 18.9 2.2 0.002 18.3 2.2 1.3 1 0 0 1 1 1 1 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.6 KFX95678.1 - 0.0048 17.0 0.8 0.0081 16.3 0.8 1.3 1 0 0 1 1 1 1 PHD-zinc-finger like domain Pput2613-deam PF14427.6 KFX95678.1 - 0.011 15.7 0.1 0.025 14.5 0.0 1.6 1 1 0 1 1 1 0 Pput_2613-like deaminase DUF35_N PF12172.8 KFX95678.1 - 0.095 12.6 1.9 5.7 6.9 0.3 3.1 2 0 0 2 2 2 0 Rubredoxin-like zinc ribbon domain (DUF35_N) PHD PF00628.29 KFX95678.1 - 0.16 11.9 2.3 0.31 11.0 2.3 1.5 1 0 0 1 1 1 0 PHD-finger YrbL-PhoP_reg PF10707.9 KFX95678.1 - 0.17 11.4 0.2 0.25 10.8 0.2 1.2 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL zf-RING-like PF08746.11 KFX95678.1 - 8.8 6.7 8.7 1.1 9.6 3.3 2.0 2 0 0 2 2 2 0 RING-like domain DEAD PF00270.29 KFX95679.1 - 4.8e-42 143.7 0.1 8.3e-42 142.9 0.1 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KFX95679.1 - 2e-33 115.0 0.0 7.2e-33 113.2 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain AAA_30 PF13604.6 KFX95679.1 - 0.00051 19.8 0.0 0.00079 19.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KFX95679.1 - 0.0014 18.9 0.0 0.013 15.8 0.1 2.2 2 0 0 2 2 2 1 AAA domain ResIII PF04851.15 KFX95679.1 - 0.0018 18.3 0.0 0.0034 17.4 0.0 1.5 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit Flavi_DEAD PF07652.14 KFX95679.1 - 0.076 13.0 0.2 0.26 11.2 0.0 2.0 2 0 0 2 2 2 0 Flavivirus DEAD domain Helicase_RecD PF05127.14 KFX95679.1 - 0.088 12.7 0.0 0.15 11.9 0.0 1.4 1 0 0 1 1 1 0 Helicase TniB PF05621.11 KFX95679.1 - 0.095 12.1 0.0 0.2 11.1 0.0 1.4 1 0 0 1 1 1 0 Bacterial TniB protein AAA_22 PF13401.6 KFX95679.1 - 0.3 11.4 1.0 1.3 9.3 1.0 2.0 1 1 0 1 1 1 0 AAA domain DUF3449 PF11931.8 KFX95680.1 - 1e-75 253.6 0.0 1.9e-75 252.7 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3449) SF3A3 PF16837.5 KFX95680.1 - 2.1e-25 89.0 0.2 9.9e-25 86.9 0.0 2.1 2 0 0 2 2 2 1 Pre-mRNA-splicing factor SF3A3, of SF3a complex, Prp9 SF3a60_bindingd PF12108.8 KFX95680.1 - 2.2e-13 49.8 0.4 4.2e-13 48.9 0.4 1.5 1 0 0 1 1 1 1 Splicing factor SF3a60 binding domain zf-met PF12874.7 KFX95680.1 - 4.3e-08 33.3 1.1 4.1e-06 27.0 0.4 2.4 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KFX95680.1 - 9.6e-08 32.1 0.4 9.6e-08 32.1 0.4 2.6 2 1 0 2 2 2 1 Zinc-finger double-stranded RNA-binding PRP9_N PF16958.5 KFX95680.1 - 0.0021 18.1 7.4 0.24 11.4 0.7 3.0 2 1 1 3 3 3 2 Pre-mRNA-splicing factor PRP9 N-terminus zf-C2H2_2 PF12756.7 KFX95680.1 - 0.0042 17.4 0.2 0.083 13.2 0.0 2.4 2 0 0 2 2 2 1 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.6 KFX95680.1 - 0.034 15.0 1.1 5.4 8.1 0.1 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger zf-U1 PF06220.12 KFX95680.1 - 0.16 11.8 0.1 0.37 10.6 0.1 1.7 1 0 0 1 1 1 0 U1 zinc finger zf-C2H2 PF00096.26 KFX95680.1 - 0.3 11.6 4.0 0.82 10.2 0.3 2.5 2 0 0 2 2 2 0 Zinc finger, C2H2 type TOM13 PF08219.11 KFX95681.1 - 1.1e-36 124.6 0.0 1.4e-36 124.3 0.0 1.1 1 0 0 1 1 1 1 Outer membrane protein TOM13 AMP-binding PF00501.28 KFX95684.1 - 4.6e-40 137.5 0.0 5.9e-40 137.1 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding PF00501.28 KFX95685.1 - 2e-38 132.1 0.0 2.5e-38 131.8 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KFX95685.1 - 2e-10 41.5 0.0 1e-07 32.8 0.0 2.6 1 1 0 1 1 1 1 AMP-binding enzyme C-terminal domain Sporozoite_P67 PF05642.11 KFX95685.1 - 0.26 9.3 3.5 0.32 9.0 3.5 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen PUF PF00806.19 KFX95692.1 - 1.7e-11 43.1 0.1 0.025 14.3 0.0 6.1 6 0 0 6 6 6 4 Pumilio-family RNA binding repeat MFS_1 PF07690.16 KFX95693.1 - 7.9e-21 74.4 38.7 2.9e-15 56.1 21.8 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KFX95693.1 - 3.4e-18 65.8 6.0 3.4e-18 65.8 6.0 2.4 2 0 0 2 2 2 2 Sugar (and other) transporter CN_hydrolase PF00795.22 KFX95694.1 - 5.7e-18 65.2 0.0 7.1e-18 64.9 0.0 1.1 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase SnoaL PF07366.12 KFX95695.1 - 3e-21 75.5 0.0 4.8e-14 52.3 0.0 2.4 2 0 0 2 2 2 2 SnoaL-like polyketide cyclase SnoaL_2 PF12680.7 KFX95695.1 - 4.8e-12 46.4 0.0 4.5e-07 30.5 0.0 2.4 2 0 0 2 2 2 2 SnoaL-like domain DUF4113 PF13438.6 KFX95696.1 - 0.21 11.7 0.0 0.44 10.7 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4113) Alpha-amylase PF00128.24 KFX95697.1 - 1.2e-115 386.7 0.0 2.4e-115 385.7 0.0 1.4 1 0 0 1 1 1 1 Alpha amylase, catalytic domain Malt_amylase_C PF16657.5 KFX95697.1 - 8.9e-09 35.3 0.0 1.8e-08 34.4 0.0 1.5 1 0 0 1 1 1 1 Maltogenic Amylase, C-terminal domain hDGE_amylase PF14701.6 KFX95697.1 - 0.00094 18.4 0.0 0.0017 17.6 0.0 1.3 1 0 0 1 1 1 1 Glycogen debranching enzyme, glucanotransferase domain Fungal_trans_2 PF11951.8 KFX95698.1 - 1.5e-51 175.4 4.5 2.3e-51 174.8 4.5 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KFX95698.1 - 2.8e-07 30.5 9.5 5.4e-07 29.6 9.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Clusterin PF01093.17 KFX95698.1 - 1.1 8.3 2.6 12 4.9 4.2 1.7 2 0 0 2 2 2 0 Clusterin Cupin_7 PF12973.7 KFX95699.1 - 1.2e-13 50.7 0.1 1.7e-13 50.3 0.1 1.2 1 0 0 1 1 1 1 ChrR Cupin-like domain DUF1202 PF06717.11 KFX95699.1 - 0.23 10.8 0.0 0.31 10.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1202) Cupin_2 PF07883.11 KFX95699.1 - 0.34 10.7 3.2 0.45 10.3 2.0 1.8 1 1 1 2 2 2 0 Cupin domain Aminotran_3 PF00202.21 KFX95700.1 - 2.6e-87 293.1 0.0 3.2e-87 292.8 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III DUF4219 PF13961.6 KFX95711.1 - 6.1e-10 38.5 0.0 9.8e-10 37.9 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4219) DUF2408 PF10303.9 KFX95711.1 - 0.044 14.4 0.0 0.068 13.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2408) Retrotran_gag_2 PF14223.6 KFX95711.1 - 0.083 12.6 0.0 0.13 11.9 0.0 1.4 1 1 0 1 1 1 0 gag-polypeptide of LTR copia-type DUF4423 PF14394.6 KFX95711.1 - 0.18 11.5 0.0 0.26 11.0 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4423) DUF4219 PF13961.6 KFX95712.1 - 2.6e-10 39.7 0.1 4.1e-10 39.1 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4219) Retrotran_gag_3 PF14244.6 KFX95712.1 - 0.03 14.1 0.1 0.083 12.7 0.1 1.6 2 0 0 2 2 2 0 gag-polypeptide of LTR copia-type Ran_BP1 PF00638.18 KFX95723.1 - 2.3e-48 163.5 2.2 5.1e-48 162.4 2.2 1.6 1 0 0 1 1 1 1 RanBP1 domain A_deaminase PF00962.22 KFX95723.1 - 6.9e-34 117.6 0.0 1e-33 117.0 0.0 1.2 1 0 0 1 1 1 1 Adenosine/AMP deaminase WH1 PF00568.23 KFX95723.1 - 0.0025 17.7 0.4 0.01 15.8 0.4 2.0 1 1 0 1 1 1 1 WH1 domain VID27_PH PF17747.1 KFX95723.1 - 0.011 16.0 0.2 0.02 15.2 0.2 1.5 1 0 0 1 1 1 0 VID27 PH-like domain YEATS PF03366.16 KFX95724.1 - 5.2e-19 68.0 0.0 1e-18 67.1 0.0 1.5 1 0 0 1 1 1 1 YEATS family BET PF17035.5 KFX95724.1 - 8.9e-08 32.2 0.3 1.8e-07 31.2 0.3 1.5 1 0 0 1 1 1 1 Bromodomain extra-terminal - transcription regulation DUF3083 PF11281.8 KFX95724.1 - 0.012 15.0 0.1 0.022 14.1 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3083) DUF4604 PF15377.6 KFX95725.1 - 1.7e-23 84.0 17.2 1.9e-23 83.8 17.2 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4604) DUF2868 PF11067.8 KFX95725.1 - 0.31 10.5 1.5 0.33 10.4 1.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2868) SRP-alpha_N PF04086.13 KFX95725.1 - 0.52 10.2 10.5 0.63 9.9 10.5 1.0 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Glyco_transf_15 PF01793.16 KFX95726.1 - 4.7e-96 321.9 12.2 3.6e-95 318.9 12.2 1.9 1 1 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase CIA30 PF08547.12 KFX95735.1 - 1.4e-45 155.2 0.0 1.9e-45 154.7 0.0 1.2 1 0 0 1 1 1 1 Complex I intermediate-associated protein 30 (CIA30) HmuY PF14064.6 KFX95735.1 - 0.066 13.4 0.1 0.16 12.2 0.0 1.6 2 0 0 2 2 2 0 HmuY protein ANAPC5 PF12862.7 KFX95736.1 - 1.8e-34 117.6 2.2 5.9e-34 116.0 2.2 1.9 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 5 TPR_19 PF14559.6 KFX95736.1 - 0.005 17.3 6.1 0.65 10.6 0.0 4.1 4 0 0 4 4 4 1 Tetratricopeptide repeat YfiO PF13525.6 KFX95736.1 - 0.072 12.8 0.7 28 4.4 0.0 3.8 4 0 0 4 4 4 0 Outer membrane lipoprotein PMAIP1 PF15150.6 KFX95736.1 - 0.074 12.9 0.2 0.21 11.5 0.2 1.8 1 0 0 1 1 1 0 Phorbol-12-myristate-13-acetate-induced DUF719 PF05334.13 KFX95736.1 - 0.19 11.9 1.4 0.34 11.1 1.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF719) TPR_10 PF13374.6 KFX95736.1 - 1.1 9.2 6.5 0.56 10.2 0.8 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.17 KFX95736.1 - 1.2 9.4 8.0 14 6.1 0.3 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.6 KFX95736.1 - 5.7 7.8 5.4 31 5.5 0.0 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_4 PF07721.14 KFX95736.1 - 6 7.8 8.1 45 5.1 1.3 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat COX6A PF02046.15 KFX95737.1 - 5.7e-52 174.9 2.3 7e-52 174.6 2.3 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIa ESSS PF10183.9 KFX95737.1 - 0.023 14.9 0.1 0.033 14.4 0.1 1.3 1 0 0 1 1 1 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) DUF4091 PF13320.6 KFX95737.1 - 0.024 14.8 1.9 0.048 13.8 0.7 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4091) Exo_endo_phos PF03372.23 KFX95738.1 - 3.4e-16 59.5 0.0 5.5e-16 58.8 0.0 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family zf-GRF PF06839.12 KFX95738.1 - 6.9e-05 22.9 2.1 0.00019 21.4 2.1 1.8 1 0 0 1 1 1 1 GRF zinc finger Exo_endo_phos_2 PF14529.6 KFX95738.1 - 0.022 14.6 0.0 1.2 9.0 0.0 2.5 2 0 0 2 2 2 0 Endonuclease-reverse transcriptase HMG_box PF00505.19 KFX95739.1 - 6e-16 58.6 0.6 1e-15 57.9 0.6 1.4 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KFX95739.1 - 0.014 15.9 0.5 0.023 15.3 0.5 1.3 1 0 0 1 1 1 0 HMG-box domain CPP1-like PF11833.8 KFX95740.1 - 0.12 12.0 0.1 0.47 10.1 0.0 1.8 2 0 0 2 2 2 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like MATalpha_HMGbox PF04769.12 KFX95741.1 - 3.3e-45 153.9 0.1 4.5e-45 153.4 0.1 1.1 1 0 0 1 1 1 1 Mating-type protein MAT alpha 1 HMG-box ANTH PF07651.16 KFX95742.1 - 2e-79 266.5 0.0 2e-79 266.5 0.0 2.6 3 1 0 3 3 3 1 ANTH domain I_LWEQ PF01608.17 KFX95742.1 - 1.6e-55 187.5 7.4 1.6e-55 187.5 7.4 6.6 4 2 2 6 6 6 3 I/LWEQ domain TcdB_N PF12918.7 KFX95742.1 - 0.051 13.9 5.2 0.068 13.5 1.9 3.2 3 0 0 3 3 3 0 TcdB toxin N-terminal helical domain DNA_pol_B PF00136.21 KFX95743.1 - 6.8e-98 328.3 0.0 9.1e-98 327.9 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.19 KFX95743.1 - 1.2e-21 77.2 0.0 1e-13 51.1 0.0 2.4 2 0 0 2 2 2 2 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.6 KFX95743.1 - 7.6e-18 64.8 6.4 1.8e-17 63.5 6.4 1.7 1 0 0 1 1 1 1 C4-type zinc-finger of DNA polymerase delta MMM1 PF10296.9 KFX95743.1 - 5.7e-05 22.3 0.0 5.7e-05 22.3 0.0 2.3 3 1 0 4 4 4 1 Maintenance of mitochondrial morphology protein 1 DZR PF12773.7 KFX95743.1 - 3.7 7.7 4.7 3.1 7.9 1.0 1.7 1 1 1 2 2 2 0 Double zinc ribbon Slu7 PF11708.8 KFX95744.1 - 1.1e-74 251.6 17.9 1.1e-74 251.6 17.9 3.0 2 1 0 2 2 2 1 Pre-mRNA splicing Prp18-interacting factor zf-CCHC_4 PF14392.6 KFX95744.1 - 0.03 14.1 0.7 0.053 13.3 0.7 1.4 1 0 0 1 1 1 0 Zinc knuckle S4 PF01479.25 KFX95745.1 - 1.1e-11 44.2 1.1 1.1e-11 44.2 1.1 2.5 3 0 0 3 3 3 1 S4 domain Ribosomal_S4 PF00163.19 KFX95745.1 - 3.5e-05 24.6 0.2 7e-05 23.7 0.2 1.6 1 0 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain Uds1 PF15456.6 KFX95745.1 - 0.086 13.0 0.4 2.4 8.3 0.0 2.2 2 0 0 2 2 2 0 Up-regulated During Septation Ribosomal_L21e PF01157.18 KFX95746.1 - 3.9e-48 161.5 6.3 9e-47 157.1 5.2 2.1 2 0 0 2 2 2 2 Ribosomal protein L21e DUF5486 PF17588.2 KFX95746.1 - 0.019 14.8 3.4 0.1 12.5 0.4 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF5486) CN_hydrolase PF00795.22 KFX95747.1 - 8.7e-13 48.2 0.0 2.7e-12 46.6 0.0 1.7 2 0 0 2 2 2 1 Carbon-nitrogen hydrolase TLP1_add_C PF18313.1 KFX95749.1 - 0.08 12.9 0.2 0.2 11.6 0.2 1.7 1 0 0 1 1 1 0 Thiolase-like protein type 1 additional C-terminal domain Abhydrolase_6 PF12697.7 KFX95750.1 - 8.8e-15 55.9 0.0 1.1e-14 55.6 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KFX95750.1 - 0.00013 21.7 0.0 0.0054 16.4 0.0 2.1 2 0 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KFX95750.1 - 0.01 15.1 0.0 0.095 12.0 0.0 2.0 2 0 0 2 2 2 0 Serine aminopeptidase, S33 Zeta_toxin PF06414.12 KFX95750.1 - 0.02 14.2 0.0 0.029 13.6 0.0 1.2 1 0 0 1 1 1 0 Zeta toxin DLH PF01738.18 KFX95750.1 - 0.081 12.5 0.0 0.14 11.7 0.0 1.4 1 0 0 1 1 1 0 Dienelactone hydrolase family CBM_1 PF00734.18 KFX95751.1 - 3.3e-06 26.9 12.3 3.3e-06 26.9 12.3 3.2 4 0 0 4 4 4 1 Fungal cellulose binding domain Esterase_phd PF10503.9 KFX95751.1 - 0.0043 16.6 0.7 0.018 14.6 0.4 2.0 1 1 0 2 2 2 1 Esterase PHB depolymerase Esterase PF00756.20 KFX95751.1 - 0.0049 16.5 0.8 0.024 14.3 0.9 1.9 1 1 0 1 1 1 1 Putative esterase Peptidase_S9 PF00326.21 KFX95751.1 - 0.0071 15.8 0.1 0.026 14.0 0.2 1.8 2 0 0 2 2 2 1 Prolyl oligopeptidase family Glyco_hydro_62 PF03664.13 KFX95752.1 - 5.9e-153 507.9 14.2 7.1e-153 507.6 14.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 62 CBM_1 PF00734.18 KFX95752.1 - 2.7e-12 46.4 16.7 9.4e-12 44.7 16.7 2.0 1 0 0 1 1 1 1 Fungal cellulose binding domain Glyco_hydro_10 PF00331.20 KFX95753.1 - 1.9e-104 349.3 0.2 2.2e-104 349.1 0.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 CBM_1 PF00734.18 KFX95753.1 - 1.1e-07 31.6 8.5 1.1e-07 31.6 8.5 2.6 3 0 0 3 3 3 1 Fungal cellulose binding domain Cellulase PF00150.18 KFX95754.1 - 3.6e-51 174.3 0.1 5e-51 173.8 0.1 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) CBM_1 PF00734.18 KFX95754.1 - 1.7e-12 47.0 14.7 1.7e-12 47.0 14.7 3.3 3 0 0 3 3 3 1 Fungal cellulose binding domain Toxin_7 PF05980.12 KFX95754.1 - 0.63 10.3 3.8 1.5 9.1 3.8 1.7 1 0 0 1 1 1 0 Toxin 7 DUF2838 PF10998.8 KFX95755.1 - 0.15 12.3 0.1 0.26 11.6 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2838) MMS1_N PF10433.9 KFX95759.1 - 1.5e-117 393.3 0.0 2.1e-117 392.8 0.0 1.2 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term CPSF_A PF03178.15 KFX95759.1 - 4.5e-69 233.2 0.0 1.4e-68 231.6 0.0 1.9 3 0 0 3 3 3 1 CPSF A subunit region Pmp3 PF01679.17 KFX95760.1 - 7.4e-20 70.9 9.5 9.3e-20 70.6 9.5 1.1 1 0 0 1 1 1 1 Proteolipid membrane potential modulator Sin_N PF04801.13 KFX95761.1 - 1.9e-33 116.3 0.0 7.2e-19 68.3 0.0 1.9 2 0 0 2 2 2 2 Sin-like protein conserved region CLP1_P PF16575.5 KFX95762.1 - 1.1e-43 149.2 0.0 1.9e-43 148.4 0.0 1.4 1 1 0 1 1 1 1 mRNA cleavage and polyadenylation factor CLP1 P-loop Clp1 PF06807.14 KFX95762.1 - 7.8e-35 119.8 0.0 1.3e-34 119.1 0.0 1.4 1 0 0 1 1 1 1 Pre-mRNA cleavage complex II protein Clp1 CLP1_N PF16573.5 KFX95762.1 - 6.2e-34 116.1 0.1 1.9e-33 114.6 0.0 1.8 2 0 0 2 2 2 1 N-terminal beta-sandwich domain of polyadenylation factor ATP_bind_1 PF03029.17 KFX95762.1 - 5e-08 33.0 0.0 5.4e-07 29.6 0.0 2.1 1 1 0 1 1 1 1 Conserved hypothetical ATP binding protein MMR_HSR1 PF01926.23 KFX95762.1 - 0.0001 22.4 0.3 0.0014 18.7 0.3 2.2 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.6 KFX95762.1 - 0.00027 21.4 0.0 0.00053 20.4 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain SRPRB PF09439.10 KFX95762.1 - 0.0039 16.7 0.0 0.0097 15.3 0.0 1.6 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit Dynamin_N PF00350.23 KFX95762.1 - 0.0042 17.2 0.3 1.1 9.2 0.0 2.5 2 1 1 3 3 3 1 Dynamin family AAA_21 PF13304.6 KFX95762.1 - 0.0056 16.5 0.0 0.0088 15.9 0.0 1.3 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system PduV-EutP PF10662.9 KFX95762.1 - 0.0087 15.8 0.0 2.3 7.9 0.0 2.3 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation SRP54 PF00448.22 KFX95762.1 - 0.016 14.8 0.0 0.53 9.9 0.0 2.2 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_24 PF13479.6 KFX95762.1 - 0.022 14.5 0.0 0.038 13.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_15 PF13175.6 KFX95762.1 - 0.022 14.5 0.0 0.033 13.9 0.0 1.1 1 0 0 1 1 1 0 AAA ATPase domain ABC_tran PF00005.27 KFX95762.1 - 0.067 13.7 0.0 0.12 12.9 0.0 1.4 1 0 0 1 1 1 0 ABC transporter MTS_N PF08468.11 KFX95762.1 - 0.11 12.6 0.0 0.19 11.8 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain N-terminal AAA_35 PF14516.6 KFX95762.1 - 0.13 11.1 0.0 0.2 10.5 0.0 1.2 1 0 0 1 1 1 0 AAA-like domain TniB PF05621.11 KFX95762.1 - 0.16 11.4 0.0 0.5 9.7 0.0 1.8 2 0 0 2 2 2 0 Bacterial TniB protein cobW PF02492.19 KFX95762.1 - 0.18 11.4 0.0 0.41 10.2 0.0 1.6 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain FeoB_N PF02421.18 KFX95762.1 - 0.22 11.0 0.1 1.8 8.0 0.0 2.1 2 0 0 2 2 2 0 Ferrous iron transport protein B Arm PF00514.23 KFX95763.1 - 0.0086 16.1 1.6 0.25 11.5 0.1 4.0 4 0 0 4 4 4 1 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 KFX95763.1 - 0.0093 16.5 0.4 3.2 8.4 0.1 3.4 2 0 0 2 2 2 1 HEAT-like repeat HEAT PF02985.22 KFX95763.1 - 0.016 15.5 0.3 3 8.3 0.1 3.2 2 0 0 2 2 2 0 HEAT repeat HEAT_2 PF13646.6 KFX95763.1 - 0.016 15.6 0.5 0.62 10.5 0.0 2.9 2 0 0 2 2 2 0 HEAT repeats BUD22 PF09073.10 KFX95763.1 - 0.15 11.4 9.6 0.23 10.8 9.6 1.2 1 0 0 1 1 1 0 BUD22 Baculo_PEP_C PF04513.12 KFX95763.1 - 0.2 11.7 2.7 2.4 8.2 0.4 2.9 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus TFIIF_alpha PF05793.12 KFX95763.1 - 0.26 9.8 8.0 0.4 9.2 8.0 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) DNA_pol_phi PF04931.13 KFX95763.1 - 1.3 7.1 19.6 2.5 6.1 19.6 1.5 1 0 0 1 1 1 0 DNA polymerase phi Nop14 PF04147.12 KFX95763.1 - 6.9 4.7 14.6 13 3.9 14.6 1.4 1 0 0 1 1 1 0 Nop14-like family NUDIX PF00293.28 KFX95764.1 - 5.6e-19 68.5 0.0 9.9e-19 67.7 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain Acetyltransf_1 PF00583.25 KFX95764.1 - 1.8e-08 34.6 0.0 1.2e-07 31.9 0.0 2.2 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KFX95764.1 - 3.8e-08 33.7 0.0 1.2e-07 32.1 0.0 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 KFX95764.1 - 5.1e-06 26.6 0.0 1.3e-05 25.3 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KFX95764.1 - 7.1e-06 26.0 0.0 1.9e-05 24.6 0.0 1.6 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 KFX95764.1 - 0.0018 18.4 0.0 0.0036 17.4 0.0 1.4 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase RPA_C PF08784.11 KFX95765.1 - 1.4e-17 64.3 0.0 4e-17 62.8 0.0 1.8 2 0 0 2 2 2 1 Replication protein A C terminal tRNA_anti-codon PF01336.25 KFX95765.1 - 6.5e-10 38.9 0.1 1.1e-09 38.1 0.1 1.3 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain RMI2 PF16100.5 KFX95765.1 - 6e-06 26.1 0.1 8.9e-06 25.5 0.1 1.2 1 0 0 1 1 1 1 RecQ-mediated genome instability protein 2 DnaJ PF00226.31 KFX95766.1 - 2.5e-14 53.1 2.1 1.1e-13 51.1 0.4 2.6 2 0 0 2 2 2 1 DnaJ domain ALMT PF11744.8 KFX95766.1 - 4.1 6.1 7.4 4 6.1 7.4 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter Lon_C PF05362.13 KFX95767.1 - 4.9e-66 222.2 0.4 9.7e-66 221.2 0.4 1.5 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain LON_substr_bdg PF02190.16 KFX95767.1 - 7.3e-28 97.9 0.0 1.8e-27 96.6 0.0 1.7 1 0 0 1 1 1 1 ATP-dependent protease La (LON) substrate-binding domain AAA PF00004.29 KFX95767.1 - 1.9e-23 83.3 0.0 6.9e-23 81.5 0.0 2.0 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 KFX95767.1 - 1.1e-08 35.2 0.0 2.8e-08 33.9 0.0 1.8 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) ChlI PF13541.6 KFX95767.1 - 3.3e-08 33.4 0.0 6.7e-08 32.4 0.0 1.5 1 0 0 1 1 1 1 Subunit ChlI of Mg-chelatase IstB_IS21 PF01695.17 KFX95767.1 - 1.3e-06 28.2 0.0 3e-06 27.1 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_16 PF13191.6 KFX95767.1 - 1.2e-05 25.7 0.0 5.1e-05 23.7 0.0 2.1 1 0 0 1 1 1 1 AAA ATPase domain AAA_2 PF07724.14 KFX95767.1 - 4.8e-05 23.5 0.0 0.00015 21.9 0.0 1.8 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) RuvB_N PF05496.12 KFX95767.1 - 5.4e-05 23.0 0.1 0.00025 20.8 0.0 2.0 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_3 PF07726.11 KFX95767.1 - 5.5e-05 23.0 0.0 0.00016 21.5 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KFX95767.1 - 0.00084 19.6 0.2 0.015 15.6 0.0 2.9 2 1 0 2 2 1 1 AAA domain TIP49 PF06068.13 KFX95767.1 - 0.0021 17.4 0.0 0.0037 16.5 0.0 1.3 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_7 PF12775.7 KFX95767.1 - 0.0038 16.8 0.0 0.0073 15.8 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_33 PF13671.6 KFX95767.1 - 0.0057 16.8 0.0 0.019 15.1 0.0 1.9 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 KFX95767.1 - 0.0065 16.8 0.0 0.024 15.0 0.0 2.0 2 0 0 2 2 1 1 RNA helicase AAA_14 PF13173.6 KFX95767.1 - 0.0072 16.4 0.0 0.018 15.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain NACHT PF05729.12 KFX95767.1 - 0.014 15.3 0.0 0.035 14.0 0.0 1.7 1 0 0 1 1 1 0 NACHT domain AAA_18 PF13238.6 KFX95767.1 - 0.028 14.9 0.0 0.07 13.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain Rad17 PF03215.15 KFX95767.1 - 0.031 14.2 0.0 0.073 13.0 0.0 1.6 1 0 0 1 1 1 0 Rad17 P-loop domain Mg_chelatase PF01078.21 KFX95767.1 - 0.032 13.6 0.2 0.096 12.1 0.2 1.8 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_23 PF13476.6 KFX95767.1 - 0.033 14.7 0.0 0.033 14.7 0.0 2.5 2 1 0 2 2 1 0 AAA domain RsgA_GTPase PF03193.16 KFX95767.1 - 0.06 13.2 0.0 0.14 12.0 0.0 1.6 1 0 0 1 1 1 0 RsgA GTPase AAA_PrkA PF08298.11 KFX95767.1 - 0.063 12.2 0.1 0.59 9.0 0.1 2.1 2 0 0 2 2 2 0 PrkA AAA domain ATPase_2 PF01637.18 KFX95767.1 - 0.065 13.1 0.0 0.97 9.3 0.0 2.7 1 1 1 2 2 2 0 ATPase domain predominantly from Archaea TsaE PF02367.17 KFX95767.1 - 0.065 13.2 0.0 0.15 12.0 0.0 1.6 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE NB-ARC PF00931.22 KFX95767.1 - 0.073 12.2 0.0 0.15 11.2 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain ABC_tran PF00005.27 KFX95767.1 - 0.083 13.4 0.0 0.31 11.5 0.0 1.9 1 0 0 1 1 1 0 ABC transporter NTPase_1 PF03266.15 KFX95767.1 - 0.092 12.6 1.0 0.27 11.1 0.1 2.1 2 1 0 2 2 2 0 NTPase AAA_24 PF13479.6 KFX95767.1 - 0.11 12.3 0.0 0.21 11.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 KFX95767.1 - 0.11 12.0 0.0 0.3 10.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.6 KFX95767.1 - 0.53 10.0 2.8 0.78 9.5 0.0 2.2 1 1 1 2 2 2 0 AAA domain Laps PF10169.9 KFX95767.1 - 1.9 9.1 6.0 0.28 11.8 0.3 2.1 1 1 1 2 2 1 0 Learning-associated protein PA PF02225.22 KFX95779.1 - 0.0071 16.3 0.0 0.038 14.0 0.0 2.1 1 1 1 2 2 2 1 PA domain Peptidase_M28 PF04389.17 KFX95779.1 - 0.01 15.5 0.1 0.045 13.4 0.0 2.0 2 0 0 2 2 2 0 Peptidase family M28 Peptidase_M20 PF01546.28 KFX95779.1 - 0.031 14.0 0.0 0.16 11.7 0.0 2.0 2 0 0 2 2 2 0 Peptidase family M20/M25/M40 Hydrolase_4 PF12146.8 KFX95780.1 - 9.3e-52 175.7 0.0 1.2e-51 175.3 0.0 1.0 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KFX95780.1 - 1e-12 48.2 0.1 7.4e-09 35.6 0.4 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KFX95780.1 - 6.5e-12 46.5 0.5 8.3e-12 46.2 0.5 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 KFX95780.1 - 1.2e-06 28.2 0.0 0.00085 18.9 0.0 2.3 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_2 PF02230.16 KFX95780.1 - 0.00081 19.2 0.1 1.3 8.8 0.0 3.1 3 0 0 3 3 3 1 Phospholipase/Carboxylesterase Chlorophyllase2 PF12740.7 KFX95780.1 - 0.0011 18.0 0.7 0.0021 17.0 0.7 1.4 1 0 0 1 1 1 1 Chlorophyllase enzyme AXE1 PF05448.12 KFX95780.1 - 0.0021 16.8 0.0 0.76 8.4 0.0 2.2 2 0 0 2 2 2 2 Acetyl xylan esterase (AXE1) Abhydrolase_8 PF06259.12 KFX95780.1 - 0.0022 17.6 0.0 0.0094 15.6 0.0 1.8 1 1 1 2 2 2 1 Alpha/beta hydrolase Ser_hydrolase PF06821.13 KFX95780.1 - 0.0034 17.2 0.0 0.0067 16.3 0.0 1.4 1 0 0 1 1 1 1 Serine hydrolase Chlorophyllase PF07224.11 KFX95780.1 - 0.0041 16.2 0.4 0.0058 15.7 0.4 1.2 1 0 0 1 1 1 1 Chlorophyllase Abhydrolase_5 PF12695.7 KFX95780.1 - 0.0093 15.7 0.0 0.017 14.9 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family PAF-AH_p_II PF03403.13 KFX95780.1 - 0.032 12.7 0.2 1.1 7.7 0.0 2.0 2 0 0 2 2 2 0 Platelet-activating factor acetylhydrolase, isoform II PGAP1 PF07819.13 KFX95780.1 - 0.069 12.9 0.1 0.11 12.1 0.1 1.3 1 0 0 1 1 1 0 PGAP1-like protein Abhydro_lipase PF04083.16 KFX95780.1 - 0.088 12.4 0.7 1.6 8.4 0.0 2.8 3 0 0 3 3 3 0 Partial alpha/beta-hydrolase lipase region Zn_clus PF00172.18 KFX95781.1 - 2.5e-05 24.3 9.3 5e-05 23.3 9.3 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Imm63 PF15599.6 KFX95781.1 - 0.00061 20.1 0.0 0.0013 19.1 0.0 1.5 1 0 0 1 1 1 1 Immunity protein 63 CFEM PF05730.11 KFX95783.1 - 4.1e-11 42.8 16.1 5.9e-11 42.3 16.1 1.2 1 0 0 1 1 1 1 CFEM domain MRI PF15325.6 KFX95783.1 - 0.22 12.6 1.6 0.38 11.8 1.6 1.4 1 0 0 1 1 1 0 Modulator of retrovirus infection Sugar_tr PF00083.24 KFX95784.1 - 8.8e-62 209.4 22.5 1e-61 209.2 22.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KFX95784.1 - 2.3e-19 69.6 38.5 2.3e-19 69.6 38.5 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily AMP-binding PF00501.28 KFX95785.1 - 8.5e-223 739.5 0.0 5.7e-75 252.5 0.0 3.3 3 0 0 3 3 3 3 AMP-binding enzyme Condensation PF00668.20 KFX95785.1 - 4.3e-145 483.9 1.1 2.4e-53 181.4 0.0 4.4 4 0 0 4 4 4 4 Condensation domain PP-binding PF00550.25 KFX95785.1 - 2.7e-35 120.6 2.7 2e-12 47.3 0.0 4.8 4 0 0 4 4 4 3 Phosphopantetheine attachment site AMP-binding_C PF13193.6 KFX95785.1 - 0.012 16.6 0.0 5.4 8.1 0.0 3.6 3 0 0 3 3 3 0 AMP-binding enzyme C-terminal domain TACC_C PF05010.14 KFX95785.1 - 0.21 11.3 0.9 0.39 10.5 0.1 1.8 2 0 0 2 2 2 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal adh_short_C2 PF13561.6 KFX95789.1 - 1.5e-58 198.1 2.1 2.6e-58 197.4 2.1 1.4 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KFX95789.1 - 3.7e-45 153.8 0.4 6e-45 153.1 0.4 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KFX95789.1 - 4.7e-12 46.2 1.2 9.1e-12 45.2 1.2 1.5 1 1 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 KFX95789.1 - 0.0055 15.9 0.0 0.0072 15.5 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Methyltransf_25 PF13649.6 KFX95789.1 - 0.091 13.5 0.1 0.3 11.8 0.1 2.0 2 0 0 2 2 2 0 Methyltransferase domain ADK PF00406.22 KFX95791.1 - 6.8e-47 159.4 0.0 8.2e-47 159.1 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 KFX95791.1 - 2.4e-39 134.9 0.1 3.3e-39 134.4 0.1 1.2 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 KFX95791.1 - 1.6e-08 35.1 0.0 2.3e-08 34.6 0.0 1.2 1 0 0 1 1 1 1 AAA domain Thymidylate_kin PF02223.17 KFX95791.1 - 3.4e-08 33.4 0.3 0.0072 16.0 0.0 2.1 1 1 1 2 2 2 2 Thymidylate kinase AAA_33 PF13671.6 KFX95791.1 - 9e-06 25.9 0.0 2.9e-05 24.2 0.0 1.8 1 1 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 KFX95791.1 - 0.013 14.8 0.2 0.033 13.4 0.2 1.7 1 1 0 1 1 1 0 Zeta toxin AAA PF00004.29 KFX95791.1 - 0.022 15.2 0.2 0.27 11.6 0.2 2.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Ploopntkinase3 PF18751.1 KFX95791.1 - 0.04 13.8 0.0 0.077 12.9 0.0 1.5 1 0 0 1 1 1 0 P-loop Nucleotide Kinase3 SRP54 PF00448.22 KFX95791.1 - 0.087 12.4 0.0 0.18 11.4 0.0 1.5 1 1 0 1 1 1 0 SRP54-type protein, GTPase domain Dicty_REP PF05086.12 KFX95799.1 - 0.34 8.8 0.3 0.51 8.3 0.3 1.2 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein MFS_1 PF07690.16 KFX95808.1 - 3.1e-23 82.3 45.2 4.6e-23 81.7 45.2 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_4 PF06779.14 KFX95808.1 - 5.1e-05 22.7 29.3 7.7e-05 22.2 29.3 1.4 1 1 0 1 1 1 1 Uncharacterised MFS-type transporter YbfB Sugar_tr PF00083.24 KFX95808.1 - 0.021 13.7 20.4 0.023 13.5 0.9 3.2 2 1 0 2 2 2 0 Sugar (and other) transporter MFS_1_like PF12832.7 KFX95808.1 - 0.039 12.8 14.9 0.79 8.5 0.0 3.6 1 1 0 2 2 2 0 MFS_1 like family Peptidase_C48 PF02902.19 KFX95809.1 - 9.7e-07 28.8 0.0 1.9e-06 27.9 0.0 1.4 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain Acetyltransf_3 PF13302.7 KFX95810.1 - 1.1e-13 52.1 0.0 1.2e-13 51.9 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KFX95810.1 - 5.3e-09 36.3 0.0 6.5e-09 36.0 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_8 PF13523.6 KFX95810.1 - 0.0028 17.4 0.0 0.0047 16.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 KFX95810.1 - 0.018 15.2 0.0 0.025 14.7 0.0 1.1 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KFX95810.1 - 0.14 12.1 0.0 0.2 11.6 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Peptidase_S10 PF00450.22 KFX95811.1 - 2e-73 248.2 0.7 3e-73 247.6 0.7 1.3 1 0 0 1 1 1 1 Serine carboxypeptidase Sulfatase PF00884.23 KFX95812.1 - 2.3e-77 260.5 0.0 2.9e-77 260.1 0.0 1.1 1 0 0 1 1 1 1 Sulfatase DUF229 PF02995.17 KFX95812.1 - 0.00012 20.8 0.0 0.0014 17.3 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF229) Phosphodiest PF01663.22 KFX95812.1 - 0.0038 16.9 0.0 0.28 10.7 0.0 2.3 2 0 0 2 2 2 1 Type I phosphodiesterase / nucleotide pyrophosphatase DUF4994 PF16385.5 KFX95812.1 - 0.0064 16.4 0.0 0.015 15.2 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function DUF4976 PF16347.5 KFX95812.1 - 0.14 12.4 0.0 0.3 11.4 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4976) Sulfatase_C PF14707.6 KFX95812.1 - 0.17 12.6 0.7 2.5 8.9 0.1 2.5 2 1 0 2 2 2 0 C-terminal region of aryl-sulfatase Sugar_tr PF00083.24 KFX95813.1 - 1.2e-114 383.7 27.0 1.4e-114 383.5 27.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KFX95813.1 - 1.6e-18 66.8 32.4 3.5e-17 62.4 26.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 KFX95813.1 - 6.6e-08 31.5 25.7 4.4e-06 25.5 5.4 3.0 3 0 0 3 3 3 2 MFS/sugar transport protein UNC-93 PF05978.16 KFX95813.1 - 2.1 8.1 15.6 1.1 9.0 1.4 2.9 3 0 0 3 3 3 0 Ion channel regulatory protein UNC-93 Rib_5-P_isom_A PF06026.14 KFX95814.1 - 2e-44 151.3 0.0 1.8e-43 148.1 0.0 2.1 1 1 0 1 1 1 1 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) Zn_clus PF00172.18 KFX95815.1 - 6.9e-20 70.9 24.4 2.2e-10 40.5 9.3 2.6 2 0 0 2 2 2 2 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KFX95815.1 - 8.1e-07 28.3 0.9 1e-06 28.0 0.0 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain Alginate_lyase2 PF08787.11 KFX95816.1 - 4e-50 170.9 0.0 4.4e-50 170.7 0.0 1.0 1 0 0 1 1 1 1 Alginate lyase Polysacc_lyase PF14099.6 KFX95816.1 - 0.00031 20.7 0.1 0.00088 19.2 0.1 1.6 1 1 0 1 1 1 1 Polysaccharide lyase Abhydrolase_3 PF07859.13 KFX95817.1 - 2.1e-33 116.0 0.0 2.9e-33 115.5 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_2 PF02230.16 KFX95817.1 - 6.3e-06 26.2 0.0 9.7e-06 25.5 0.0 1.2 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_6 PF12697.7 KFX95817.1 - 0.00038 21.1 0.0 0.00052 20.7 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family COesterase PF00135.28 KFX95817.1 - 0.00055 18.9 0.6 0.0046 15.9 0.0 2.0 2 0 0 2 2 2 1 Carboxylesterase family DLH PF01738.18 KFX95817.1 - 0.024 14.2 0.0 0.039 13.5 0.0 1.2 1 0 0 1 1 1 0 Dienelactone hydrolase family Esterase_phd PF10503.9 KFX95817.1 - 0.063 12.8 1.0 1.7 8.1 0.1 2.2 2 0 0 2 2 2 0 Esterase PHB depolymerase DUF2974 PF11187.8 KFX95817.1 - 0.11 12.1 0.0 0.16 11.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) AXE1 PF05448.12 KFX95817.1 - 0.15 10.7 0.1 0.3 9.7 0.0 1.4 2 0 0 2 2 2 0 Acetyl xylan esterase (AXE1) Say1_Mug180 PF10340.9 KFX95817.1 - 0.16 10.8 0.0 0.33 9.8 0.0 1.5 2 0 0 2 2 2 0 Steryl acetyl hydrolase RTA1 PF04479.13 KFX95818.1 - 1.2e-67 227.6 12.1 1.7e-67 227.1 12.1 1.2 1 0 0 1 1 1 1 RTA1 like protein PhrC_PhrF PF11131.8 KFX95818.1 - 0.55 9.9 5.3 3.4 7.3 1.0 2.9 2 0 0 2 2 2 0 Rap-phr extracellular signalling DUF3112 PF11309.8 KFX95818.1 - 0.79 9.1 3.5 1.1 8.7 0.4 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3112) Thioesterase PF00975.20 KFX95819.1 - 1.2e-11 45.1 0.1 2.2e-11 44.3 0.0 1.4 2 0 0 2 2 2 1 Thioesterase domain Abhydrolase_6 PF12697.7 KFX95819.1 - 3.2e-06 27.9 0.9 3.8e-06 27.6 0.9 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KFX95819.1 - 0.00038 20.2 0.1 0.0012 18.5 0.1 1.7 2 0 0 2 2 2 1 alpha/beta hydrolase fold DUF2974 PF11187.8 KFX95819.1 - 0.15 11.6 0.0 0.22 11.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Abhydrolase_6 PF12697.7 KFX95820.1 - 2.6e-08 34.7 0.5 4.2e-07 30.8 0.2 2.1 1 1 1 2 2 2 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KFX95820.1 - 4.1e-07 29.5 0.0 1.4e-06 27.8 0.0 1.8 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 KFX95820.1 - 5.8e-07 29.2 0.2 1.6e-06 27.8 0.0 1.8 2 0 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_1 PF00561.20 KFX95820.1 - 6.7e-07 29.2 0.0 1.6e-06 28.0 0.0 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold DLH PF01738.18 KFX95820.1 - 0.03 13.9 0.0 0.41 10.2 0.0 2.3 2 0 0 2 2 2 0 Dienelactone hydrolase family BAAT_C PF08840.11 KFX95820.1 - 0.13 12.1 0.0 0.57 10.1 0.0 1.9 1 1 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal PAF-AH_p_II PF03403.13 KFX95820.1 - 0.15 10.5 0.0 0.23 10.0 0.0 1.2 1 0 0 1 1 1 0 Platelet-activating factor acetylhydrolase, isoform II MFS_1 PF07690.16 KFX95821.1 - 1.2e-35 123.1 79.9 2.7e-28 98.9 53.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Fungal_trans PF04082.18 KFX95822.1 - 3.4e-14 52.5 0.2 5.7e-14 51.8 0.2 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain RNB PF00773.19 KFX95822.1 - 0.03 13.7 0.0 0.054 12.8 0.0 1.3 1 0 0 1 1 1 0 RNB domain COesterase PF00135.28 KFX95824.1 - 8.7e-71 239.3 0.0 7.7e-70 236.2 0.0 1.9 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KFX95824.1 - 3.4e-14 53.2 1.1 2.4e-13 50.4 1.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KFX95824.1 - 0.00078 19.0 0.2 0.0015 18.0 0.2 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family ThrE_2 PF12821.7 KFX95824.1 - 0.11 12.6 0.1 0.26 11.4 0.1 1.5 1 0 0 1 1 1 0 Threonine/Serine exporter, ThrE GMC_oxred_N PF00732.19 KFX95825.1 - 2.8e-62 210.8 0.0 4.2e-62 210.2 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KFX95825.1 - 1e-29 103.9 0.3 2.1e-29 102.9 0.3 1.6 1 0 0 1 1 1 1 GMC oxidoreductase F-box-like PF12937.7 KFX95825.1 - 1.4e-09 37.7 0.1 2.7e-09 36.8 0.1 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KFX95825.1 - 4.9e-09 35.9 0.0 1.1e-08 34.8 0.0 1.5 1 0 0 1 1 1 1 F-box domain DAO PF01266.24 KFX95825.1 - 0.0056 16.3 0.0 0.019 14.5 0.0 1.9 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KFX95825.1 - 0.006 16.8 0.3 0.025 14.8 0.0 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain F-box_4 PF15966.5 KFX95825.1 - 0.0081 16.0 0.0 0.017 15.0 0.0 1.5 1 0 0 1 1 1 1 F-box Thi4 PF01946.17 KFX95825.1 - 0.079 12.2 0.3 0.16 11.2 0.0 1.6 2 0 0 2 2 2 0 Thi4 family HSP20 PF00011.21 KFX95826.1 - 1.7e-17 63.4 0.0 1.6e-12 47.4 0.1 2.3 2 0 0 2 2 2 2 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 KFX95826.1 - 0.1 12.2 0.0 0.39 10.3 0.0 1.9 2 0 0 2 2 2 0 HSP20-like domain found in ArsA MFS_1 PF07690.16 KFX95827.1 - 2.9e-05 23.2 31.9 0.00033 19.7 29.0 2.7 1 1 1 2 2 2 2 Major Facilitator Superfamily OST3_OST6 PF04756.13 KFX95827.1 - 0.027 13.8 1.1 0.086 12.2 1.1 1.8 1 0 0 1 1 1 0 OST3 / OST6 family, transporter family Glyoxalase PF00903.25 KFX95828.1 - 6.7e-05 23.1 0.0 8.3e-05 22.8 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Fungal_trans_2 PF11951.8 KFX95829.1 - 1.9e-06 27.0 0.7 3.7e-06 26.0 0.2 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain MFS_1 PF07690.16 KFX95830.1 - 3.5e-14 52.5 32.7 4.6e-14 52.1 32.7 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily p450 PF00067.22 KFX95831.1 - 1.2e-15 57.3 0.0 8.5e-15 54.4 0.0 2.0 1 1 0 1 1 1 1 Cytochrome P450 Pro_CA PF00484.19 KFX95831.1 - 0.00021 21.6 0.0 0.00043 20.6 0.0 1.5 1 0 0 1 1 1 1 Carbonic anhydrase ATP-synt_C PF00137.21 KFX95832.1 - 1.8e-29 101.8 34.1 2.3e-19 69.5 16.6 2.2 2 0 0 2 2 2 2 ATP synthase subunit C LPD23 PF18838.1 KFX95832.1 - 0.48 10.2 2.9 0.73 9.6 2.9 1.3 1 0 0 1 1 1 0 Large polyvalent protein associated domain 23 MARVEL PF01284.23 KFX95833.1 - 7.2e-14 52.0 12.3 8.5e-14 51.8 12.3 1.0 1 0 0 1 1 1 1 Membrane-associating domain Fungal_trans PF04082.18 KFX95834.1 - 3.6e-29 101.6 0.0 5.3e-29 101.1 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KFX95834.1 - 1.1e-10 41.4 11.7 1.8e-10 40.7 11.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pput2613-deam PF14427.6 KFX95834.1 - 0.16 11.9 0.6 5.7 6.9 0.0 2.3 2 0 0 2 2 2 0 Pput_2613-like deaminase FSH1 PF03959.13 KFX95843.1 - 9.7e-28 97.3 0.0 1.1e-27 97.2 0.0 1.1 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Thioesterase PF00975.20 KFX95843.1 - 0.011 15.9 0.1 0.024 14.8 0.0 1.6 1 1 1 2 2 2 0 Thioesterase domain Abhydrolase_6 PF12697.7 KFX95843.1 - 0.028 15.0 0.0 0.036 14.7 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family His_Phos_1 PF00300.22 KFX95843.1 - 0.17 11.6 0.0 0.42 10.3 0.0 1.6 2 0 0 2 2 2 0 Histidine phosphatase superfamily (branch 1) zf-FPG_IleRS PF06827.14 KFX95844.1 - 1.4e-05 24.8 1.1 0.032 14.1 0.0 2.4 2 0 0 2 2 2 2 Zinc finger found in FPG and IleRS WD40 PF00400.32 KFX95850.1 - 2.5e-16 59.8 10.0 4.3e-06 27.3 0.6 4.6 5 0 0 5 5 5 3 WD domain, G-beta repeat Nup160 PF11715.8 KFX95850.1 - 3.2e-06 26.1 0.8 0.038 12.6 0.1 3.0 1 1 2 3 3 3 3 Nucleoporin Nup120/160 ANAPC4_WD40 PF12894.7 KFX95850.1 - 6.9e-06 26.3 0.0 0.36 11.2 0.0 3.3 2 1 1 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain PAT1 PF09770.9 KFX95851.1 - 0 1275.8 17.5 0 1275.5 17.5 1.0 1 0 0 1 1 1 1 Topoisomerase II-associated protein PAT1 Herpes_HEPA PF03324.14 KFX95851.1 - 0.11 13.0 0.0 0.28 11.7 0.0 1.6 1 0 0 1 1 1 0 Herpesvirus DNA helicase/primase complex associated protein DAGK_cat PF00781.24 KFX95857.1 - 2.6e-14 52.9 0.0 3.8e-14 52.4 0.0 1.2 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain Lys PF00062.20 KFX95858.1 - 0.00017 21.8 0.1 0.00022 21.5 0.1 1.2 1 0 0 1 1 1 1 C-type lysozyme/alpha-lactalbumin family Fungal_trans PF04082.18 KFX95859.1 - 3.4e-24 85.3 0.0 5.5e-24 84.6 0.0 1.4 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KFX95859.1 - 4e-09 36.5 9.4 6.1e-09 35.9 9.4 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ccdc124 PF06244.12 KFX95860.1 - 1.7e-27 96.5 20.4 1.7e-27 96.5 20.4 2.3 2 1 0 2 2 2 1 Coiled-coil domain-containing protein 124 /Oxs1 SbsC_C PF18058.1 KFX95860.1 - 0.012 15.9 1.1 0.012 15.9 1.1 3.1 2 1 0 2 2 2 0 SbsC C-terminal domain Bud13 PF09736.9 KFX95860.1 - 0.65 10.4 25.4 1.1 9.6 12.2 2.3 2 0 0 2 2 2 0 Pre-mRNA-splicing factor of RES complex CRT10 PF08728.10 KFX95860.1 - 2.2 6.3 3.8 2.6 6.1 3.8 1.0 1 0 0 1 1 1 0 CRT10 UQ_con PF00179.26 KFX95861.1 - 5.8e-09 35.7 0.0 1e-08 34.9 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 KFX95861.1 - 0.14 12.5 0.0 0.29 11.4 0.0 1.5 1 0 0 1 1 1 0 RWD domain MAD PF05557.13 KFX95862.1 - 1.5e-57 195.5 54.1 3.1e-57 194.4 54.1 1.5 1 1 0 1 1 1 1 Mitotic checkpoint protein Intimin_C PF07979.11 KFX95862.1 - 0.16 12.4 0.0 0.62 10.5 0.0 2.0 1 0 0 1 1 1 0 Intimin C-type lectin domain YqjK PF13997.6 KFX95862.1 - 0.69 10.2 3.9 2.9 8.2 0.0 3.3 3 0 0 3 3 3 0 YqjK-like protein Diphthami_syn_2 PF01902.17 KFX95866.1 - 9.3e-13 48.2 0.0 3.7e-06 26.6 0.0 3.1 3 0 0 3 3 3 3 Diphthamide synthase BNR_2 PF13088.6 KFX95873.1 - 1.2e-21 77.2 0.4 1.5e-20 73.7 0.4 2.0 1 1 0 1 1 1 1 BNR repeat-like domain BNR PF02012.20 KFX95873.1 - 3.9e-07 29.1 22.3 0.11 12.5 0.4 5.9 5 0 0 5 5 5 5 BNR/Asp-box repeat BNR_3 PF13859.6 KFX95873.1 - 0.00065 19.1 0.0 0.0012 18.2 0.0 1.4 1 1 0 1 1 1 1 BNR repeat-like domain CHB_HEX_C PF03174.13 KFX95873.1 - 0.0052 16.7 0.7 10 6.2 0.0 4.1 5 0 0 5 5 5 1 Chitobiase/beta-hexosaminidase C-terminal domain Sortilin-Vps10 PF15902.5 KFX95873.1 - 0.37 9.5 10.6 3.3 6.4 0.1 3.6 2 2 1 4 4 4 0 Sortilin, neurotensin receptor 3, Pkinase PF00069.25 KFX95874.1 - 0.13 11.6 0.0 0.16 11.3 0.0 1.1 1 0 0 1 1 1 0 Protein kinase domain RNase_H PF00075.24 KFX95875.1 - 4.2e-14 52.9 0.0 5.6e-14 52.5 0.0 1.1 1 0 0 1 1 1 1 RNase H MU117 PF15474.6 KFX95876.1 - 0.00045 21.0 8.2 0.00067 20.4 8.2 1.3 1 0 0 1 1 1 1 Meiotically up-regulated gene family COX3 PF00510.18 KFX95876.1 - 0.055 13.3 0.0 0.08 12.8 0.0 1.2 1 0 0 1 1 1 0 Cytochrome c oxidase subunit III Tannase PF07519.11 KFX95878.1 - 1.3e-05 24.4 0.2 1.6e-05 24.0 0.2 1.1 1 0 0 1 1 1 1 Tannase and feruloyl esterase DUF2518 PF10726.9 KFX95878.1 - 0.17 11.6 1.2 0.23 11.1 1.2 1.2 1 0 0 1 1 1 0 Protein of function (DUF2518) Tannase PF07519.11 KFX95879.1 - 1.4e-93 314.3 0.5 1.8e-93 314.0 0.5 1.0 1 0 0 1 1 1 1 Tannase and feruloyl esterase O-FucT PF10250.9 KFX95881.1 - 1.3e-13 51.4 0.0 6.3e-12 45.8 0.0 2.7 1 1 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase Tetraspanin PF00335.20 KFX95882.1 - 0.0093 15.7 0.6 0.011 15.5 0.6 1.0 1 0 0 1 1 1 1 Tetraspanin family MRVI1 PF05781.12 KFX95882.1 - 0.26 9.9 0.0 0.31 9.7 0.0 1.0 1 0 0 1 1 1 0 MRVI1 protein NAD_kinase PF01513.21 KFX95885.1 - 4.2e-78 262.5 0.0 7e-78 261.8 0.0 1.3 1 0 0 1 1 1 1 ATP-NAD kinase RNase_PH PF01138.21 KFX95886.1 - 4.2e-14 53.2 0.3 6.3e-14 52.6 0.3 1.2 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 KFX95886.1 - 0.034 14.2 0.0 0.066 13.2 0.0 1.5 1 0 0 1 1 1 0 3' exoribonuclease family, domain 2 PTPA PF03095.15 KFX95887.1 - 1.1e-113 379.7 0.0 1.3e-113 379.4 0.0 1.1 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein FAA_hydrolase PF01557.18 KFX95888.1 - 8.6e-64 215.2 0.0 1.1e-63 214.9 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family Complex1_LYR PF05347.15 KFX95889.1 - 6.8e-18 64.5 2.3 8e-18 64.3 2.3 1.1 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 KFX95889.1 - 3.1e-05 24.6 1.0 3.5e-05 24.5 1.0 1.1 1 0 0 1 1 1 1 Complex1_LYR-like RhoGAP PF00620.27 KFX95891.1 - 5.9e-43 146.3 0.1 1.4e-42 145.1 0.1 1.6 1 0 0 1 1 1 1 RhoGAP domain PH PF00169.29 KFX95891.1 - 6.4e-14 52.3 0.0 1.7e-13 51.0 0.0 1.8 1 0 0 1 1 1 1 PH domain PX PF00787.24 KFX95891.1 - 0.0054 16.7 0.0 0.014 15.4 0.0 1.7 1 0 0 1 1 1 1 PX domain PH_8 PF15409.6 KFX95891.1 - 0.02 15.2 0.0 0.19 12.1 0.0 2.3 2 0 0 2 2 2 0 Pleckstrin homology domain DUF3450 PF11932.8 KFX95891.1 - 0.16 11.3 1.8 0.3 10.4 1.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) TPR_12 PF13424.6 KFX95907.1 - 7.6e-10 38.9 33.5 0.057 13.7 0.0 9.7 10 1 2 12 12 12 5 Tetratricopeptide repeat AAA_22 PF13401.6 KFX95907.1 - 2.9e-09 37.3 1.0 1.5e-08 35.0 0.1 2.8 2 0 0 2 2 2 1 AAA domain TPR_14 PF13428.6 KFX95907.1 - 1.6e-06 28.5 1.7 16 6.6 0.0 7.9 9 0 0 9 9 9 0 Tetratricopeptide repeat TPR_19 PF14559.6 KFX95907.1 - 8.9e-06 26.1 13.8 0.042 14.4 0.1 8.3 11 0 0 11 11 9 2 Tetratricopeptide repeat TPR_10 PF13374.6 KFX95907.1 - 5.2e-05 23.0 10.7 3.9 7.5 0.0 7.0 6 0 0 6 6 6 2 Tetratricopeptide repeat AAA_16 PF13191.6 KFX95907.1 - 6.6e-05 23.4 0.1 0.00028 21.3 0.1 2.2 1 0 0 1 1 1 1 AAA ATPase domain DUF3137 PF11335.8 KFX95907.1 - 0.00054 19.9 0.1 0.0036 17.3 0.0 2.4 1 1 1 2 2 2 1 Protein of unknown function (DUF3137) TPR_16 PF13432.6 KFX95907.1 - 0.0012 19.4 0.1 30 5.4 0.0 6.8 8 0 0 8 8 8 0 Tetratricopeptide repeat TPR_7 PF13176.6 KFX95907.1 - 0.0037 17.2 17.2 14 5.9 0.1 9.0 9 0 0 9 9 9 0 Tetratricopeptide repeat NACHT PF05729.12 KFX95907.1 - 0.0061 16.5 0.0 0.061 13.2 0.0 2.6 2 0 0 2 2 2 1 NACHT domain TPR_2 PF07719.17 KFX95907.1 - 0.012 15.6 19.7 9.4 6.6 0.1 8.6 9 0 0 9 9 8 0 Tetratricopeptide repeat TPR_8 PF13181.6 KFX95907.1 - 0.068 13.4 19.8 0.64 10.4 0.4 8.1 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_1 PF00515.28 KFX95907.1 - 8.8 6.3 15.8 10 6.2 0.1 6.8 8 0 0 8 8 7 0 Tetratricopeptide repeat Thiolase_N PF00108.23 KFX95908.1 - 1.4e-15 57.4 0.0 1.2e-14 54.4 0.0 2.3 2 1 0 2 2 2 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 KFX95908.1 - 2.8e-12 46.4 2.3 7e-11 41.8 0.0 2.7 2 1 1 3 3 3 2 Thiolase, C-terminal domain ACP_syn_III PF08545.10 KFX95908.1 - 3.4e-05 23.6 0.1 0.002 17.9 0.0 2.7 3 0 0 3 3 3 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III ketoacyl-synt PF00109.26 KFX95908.1 - 0.0015 18.1 0.0 0.0038 16.8 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 KFX95908.1 - 0.077 13.0 0.1 13 5.9 0.0 2.7 2 0 0 2 2 2 0 Beta-ketoacyl synthase, C-terminal domain DAO PF01266.24 KFX95909.1 - 2.5e-52 178.6 0.0 4e-52 177.9 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase DAO_C PF16901.5 KFX95909.1 - 1.4e-45 154.2 0.1 2.6e-45 153.4 0.1 1.5 1 0 0 1 1 1 1 C-terminal domain of alpha-glycerophosphate oxidase FAD_binding_2 PF00890.24 KFX95909.1 - 4.8e-09 35.8 0.5 1.3e-08 34.4 0.5 1.7 1 1 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.7 KFX95909.1 - 3.2e-05 23.5 0.1 0.00024 20.6 0.0 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KFX95909.1 - 0.00063 19.1 0.1 0.0014 17.9 0.0 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KFX95909.1 - 0.0013 18.9 0.1 0.0041 17.3 0.1 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 KFX95909.1 - 0.027 13.7 0.2 0.057 12.7 0.2 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KFX95909.1 - 0.027 13.2 0.2 0.047 12.4 0.2 1.3 1 0 0 1 1 1 0 HI0933-like protein Pyr_redox PF00070.27 KFX95909.1 - 0.029 14.9 0.2 0.087 13.4 0.2 1.8 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 KFX95909.1 - 0.065 12.3 0.3 0.31 10.1 0.3 1.9 2 0 0 2 2 2 0 Glucose inhibited division protein A FAD_binding_3 PF01494.19 KFX95909.1 - 0.075 12.3 0.6 0.22 10.7 0.6 1.8 1 1 0 1 1 1 0 FAD binding domain 3HCDH_N PF02737.18 KFX95909.1 - 0.14 12.0 0.9 0.23 11.3 0.1 1.8 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Lycopene_cycl PF05834.12 KFX95909.1 - 0.15 11.0 0.3 1 8.3 0.2 2.2 3 0 0 3 3 3 0 Lycopene cyclase protein PPR_2 PF13041.6 KFX95910.1 - 3.2e-19 68.8 0.0 1.3e-08 34.9 0.0 5.1 5 1 1 6 6 6 4 PPR repeat family PPR_3 PF13812.6 KFX95910.1 - 5.4e-12 45.6 0.0 9.2e-07 28.9 0.0 4.4 4 1 1 5 5 5 2 Pentatricopeptide repeat domain PPR PF01535.20 KFX95910.1 - 1.9e-11 43.4 0.1 0.0075 16.4 0.0 5.8 6 0 0 6 6 6 3 PPR repeat PPR_long PF17177.4 KFX95910.1 - 6.8e-08 32.1 0.0 0.0052 16.2 0.0 3.2 3 0 0 3 3 3 2 Pentacotripeptide-repeat region of PRORP PPR_1 PF12854.7 KFX95910.1 - 1.8e-06 27.5 0.0 0.15 11.8 0.0 4.8 5 0 0 5 5 5 2 PPR repeat G-7-MTase PF12803.7 KFX95910.1 - 0.035 13.3 0.0 0.059 12.5 0.0 1.3 1 0 0 1 1 1 0 mRNA (guanine-7-)methyltransferase (G-7-MTase) TPR_14 PF13428.6 KFX95910.1 - 0.15 13.0 0.0 41 5.4 0.0 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat cwf18 PF08315.12 KFX95911.1 - 5.8e-46 156.5 6.1 5.8e-46 156.5 6.1 1.7 2 0 0 2 2 2 1 cwf18 pre-mRNA splicing factor zf-CCHC_3 PF13917.6 KFX95912.1 - 5e-20 71.2 1.8 1.2e-19 70.0 1.8 1.7 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_5 PF14787.6 KFX95912.1 - 0.02 14.6 0.4 0.045 13.5 0.4 1.6 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger zf-CCHC PF00098.23 KFX95912.1 - 0.18 12.0 1.3 0.29 11.3 1.3 1.3 1 0 0 1 1 1 0 Zinc knuckle SUZ PF12752.7 KFX95913.1 - 2e-17 63.7 1.8 2e-17 63.7 1.8 2.7 2 0 0 2 2 2 1 SUZ domain R3H PF01424.22 KFX95913.1 - 1.2e-08 34.8 0.1 2.4e-08 33.8 0.1 1.5 1 0 0 1 1 1 1 R3H domain Ribosomal_L17 PF01196.19 KFX95914.1 - 2.7e-33 114.7 0.0 5.3e-33 113.8 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L17 Molybdopterin_N PF18364.1 KFX95914.1 - 0.087 12.9 0.0 0.17 11.9 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin oxidoreductase N-terminal domain DUF3552 PF12072.8 KFX95914.1 - 0.39 10.1 3.8 1.4 8.3 0.1 2.5 2 1 1 3 3 3 0 Domain of unknown function (DUF3552) Zn_clus PF00172.18 KFX95917.1 - 8e-06 25.9 9.2 1.6e-05 24.9 9.2 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KFX95917.1 - 0.018 14.1 0.6 0.034 13.2 0.4 1.6 1 1 0 1 1 1 0 Fungal specific transcription factor domain DUF2039 PF10217.9 KFX95917.1 - 0.37 11.2 5.1 0.61 10.5 3.1 2.1 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2039) adh_short PF00106.25 KFX95918.1 - 3.4e-15 56.0 0.2 3.7e-15 55.9 0.2 1.0 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KFX95918.1 - 1.5e-07 31.3 0.3 1.7e-07 31.1 0.3 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 KFX95918.1 - 0.00028 20.4 0.0 0.0003 20.4 0.0 1.0 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 KFX95918.1 - 0.00062 19.7 0.1 0.00064 19.7 0.1 1.1 1 0 0 1 1 1 1 NAD(P)H-binding KR PF08659.10 KFX95918.1 - 0.0072 16.3 0.2 0.0078 16.1 0.2 1.1 1 0 0 1 1 1 1 KR domain RmlD_sub_bind PF04321.17 KFX95918.1 - 0.06 12.4 0.0 0.063 12.4 0.0 1.1 1 0 0 1 1 1 0 RmlD substrate binding domain GDP_Man_Dehyd PF16363.5 KFX95918.1 - 0.096 12.1 0.0 0.096 12.1 0.0 1.1 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase MFS_1 PF07690.16 KFX95922.1 - 8.8e-47 159.7 32.1 1.2e-46 159.3 32.1 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KFX95922.1 - 7.9e-12 44.8 6.2 7.9e-12 44.8 6.2 1.9 2 1 1 3 3 3 1 Sugar (and other) transporter MFS_4 PF06779.14 KFX95922.1 - 9.9e-06 25.1 8.4 9.9e-06 25.1 8.4 1.7 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB TRI12 PF06609.13 KFX95922.1 - 0.00034 19.2 4.5 0.00051 18.6 4.5 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) SnoaL_4 PF13577.6 KFX95923.1 - 7.2e-20 71.4 0.0 8.7e-20 71.1 0.0 1.1 1 0 0 1 1 1 1 SnoaL-like domain DUF4440 PF14534.6 KFX95923.1 - 1.8e-05 25.1 0.0 6.1e-05 23.4 0.0 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF4440) Ring_hydroxyl_B PF00866.18 KFX95923.1 - 0.029 14.5 0.0 0.062 13.4 0.0 1.6 1 1 1 2 2 2 0 Ring hydroxylating beta subunit MFS_1 PF07690.16 KFX95926.1 - 3.4e-18 65.7 66.8 1.6e-15 56.9 38.5 2.8 2 1 1 3 3 3 2 Major Facilitator Superfamily TRI12 PF06609.13 KFX95926.1 - 2.1e-09 36.4 24.7 4.7e-09 35.2 24.5 1.6 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Ferric_reduct PF01794.19 KFX95927.1 - 6.7e-16 58.6 10.3 6.7e-16 58.6 10.3 1.7 2 0 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 KFX95927.1 - 6.8e-08 32.8 0.1 0.012 15.7 0.0 2.4 1 1 1 2 2 2 2 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 KFX95927.1 - 6.7e-05 22.9 0.1 0.00097 19.2 0.0 2.4 2 1 0 2 2 2 1 FAD-binding domain DUF2183 PF09949.9 KFX95928.1 - 6.2e-20 71.4 0.1 1.1e-19 70.5 0.1 1.4 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2183) Peptidase_C12 PF01088.21 KFX95929.1 - 1e-53 182.2 0.0 1.2e-53 182.0 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 adh_short_C2 PF13561.6 KFX95930.1 - 4.3e-56 190.1 0.5 5.2e-56 189.8 0.5 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KFX95930.1 - 4.1e-48 163.4 0.6 5.3e-48 163.1 0.6 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KFX95930.1 - 2.8e-13 50.2 0.7 4.4e-13 49.5 0.7 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KFX95930.1 - 0.00053 19.5 0.3 0.0014 18.1 0.3 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 2-Hacid_dh_C PF02826.19 KFX95930.1 - 0.11 11.9 0.0 0.17 11.2 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NusB PF01029.18 KFX95930.1 - 0.17 12.1 0.0 0.28 11.4 0.0 1.3 1 0 0 1 1 1 0 NusB family Nop PF01798.18 KFX95936.1 - 2e-45 155.1 0.0 2.8e-45 154.6 0.0 1.2 1 0 0 1 1 1 1 snoRNA binding domain, fibrillarin Acetate_kinase PF00871.17 KFX95937.1 - 1.5e-82 277.4 0.1 5.6e-63 213.0 0.0 2.0 1 1 1 2 2 2 2 Acetokinase family GST_N_3 PF13417.6 KFX95938.1 - 6.5e-18 64.9 0.1 4e-17 62.4 0.0 2.1 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KFX95938.1 - 7.1e-12 45.5 1.3 1.1e-11 44.9 0.0 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 KFX95938.1 - 1.2e-06 28.8 0.0 2.4e-06 27.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KFX95938.1 - 3.9e-05 23.6 0.2 9.6e-05 22.3 0.2 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_5 PF16865.5 KFX95938.1 - 0.0019 18.7 0.0 0.0035 17.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain HAT PF02184.16 KFX95939.1 - 5.4e-26 90.3 67.8 3.2e-12 46.2 1.6 14.1 15 0 0 15 15 15 6 HAT (Half-A-TPR) repeat TPR_14 PF13428.6 KFX95939.1 - 1.3e-20 72.3 32.8 0.0012 19.4 0.2 11.9 7 3 5 12 12 12 6 Tetratricopeptide repeat TPR_19 PF14559.6 KFX95939.1 - 8.9e-20 71.0 2.3 1.4e-05 25.5 0.0 7.2 6 1 2 8 8 8 4 Tetratricopeptide repeat Suf PF05843.14 KFX95939.1 - 8.4e-13 49.0 22.0 6.1e-05 23.1 1.5 6.1 2 1 4 7 7 7 3 Suppressor of forked protein (Suf) TPR_2 PF07719.17 KFX95939.1 - 1.2e-11 43.8 19.1 0.51 10.6 0.0 10.5 11 0 0 11 11 11 2 Tetratricopeptide repeat TPR_17 PF13431.6 KFX95939.1 - 6.1e-07 29.4 7.0 0.041 14.3 0.1 6.8 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_8 PF13181.6 KFX95939.1 - 2.3e-06 27.4 10.4 5.1 7.6 0.0 7.8 8 0 0 8 8 7 2 Tetratricopeptide repeat U3_assoc_6 PF08640.11 KFX95939.1 - 6e-06 26.2 19.5 0.046 13.8 1.3 6.8 5 1 1 6 6 6 2 U3 small nucleolar RNA-associated protein 6 TPR_15 PF13429.6 KFX95939.1 - 0.0013 18.0 16.9 0.078 12.2 3.2 4.9 1 1 5 6 6 6 2 Tetratricopeptide repeat TPR_16 PF13432.6 KFX95939.1 - 0.0024 18.5 13.8 24 5.7 0.0 7.8 9 1 0 9 9 9 0 Tetratricopeptide repeat Mad3_BUB1_I PF08311.12 KFX95939.1 - 0.015 15.3 17.6 1.9 8.5 1.1 6.3 4 2 1 5 5 5 0 Mad3/BUB1 homology region 1 TPR_6 PF13174.6 KFX95939.1 - 0.025 15.2 21.7 8.5 7.3 0.0 9.1 11 0 0 11 11 10 0 Tetratricopeptide repeat NRDE-2 PF08424.10 KFX95939.1 - 0.091 11.9 25.0 1.6 7.8 1.3 5.6 3 3 2 5 5 5 0 NRDE-2, necessary for RNA interference PBP_GOBP PF01395.22 KFX95939.1 - 0.13 12.4 0.0 0.37 10.9 0.0 1.7 1 0 0 1 1 1 0 PBP/GOBP family Fis1_TPR_C PF14853.6 KFX95939.1 - 0.17 12.0 9.2 37 4.5 0.7 5.6 6 0 0 6 6 6 0 Fis1 C-terminal tetratricopeptide repeat ANAPC3 PF12895.7 KFX95939.1 - 0.33 11.2 7.6 1.5 9.1 0.0 4.8 7 0 0 7 7 5 0 Anaphase-promoting complex, cyclosome, subunit 3 HMG_box PF00505.19 KFX95940.1 - 1.9e-13 50.6 2.5 5.9e-09 36.2 0.4 3.5 3 2 0 3 3 3 2 HMG (high mobility group) box HMG_box_2 PF09011.10 KFX95940.1 - 1.4e-10 41.6 9.1 4.9e-07 30.3 0.0 3.0 3 1 0 3 3 3 2 HMG-box domain DUF2561 PF10812.8 KFX95940.1 - 2.1 8.3 7.2 1 9.4 3.6 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2561) DUF5521 PF17659.1 KFX95940.1 - 6.8 4.4 7.7 6.5 4.5 4.3 1.9 2 0 0 2 2 2 0 Family of unknown function (DUF5521) Carb_anhydrase PF00194.21 KFX95976.1 - 1.2e-29 103.6 0.0 7.5e-14 51.9 0.0 2.2 2 0 0 2 2 2 2 Eukaryotic-type carbonic anhydrase Sugar_tr PF00083.24 KFX95977.1 - 3.8e-68 230.4 28.5 4.7e-68 230.1 28.5 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KFX95977.1 - 1.3e-19 70.3 44.7 1.2e-12 47.5 24.4 2.4 1 1 2 3 3 3 2 Major Facilitator Superfamily AEP1 PF17049.5 KFX95977.1 - 0.085 11.9 0.0 0.13 11.3 0.0 1.2 1 0 0 1 1 1 0 ATPase expression protein 1 PIG-L PF02585.17 KFX95979.1 - 5.6e-26 91.7 0.0 9.7e-26 90.9 0.0 1.4 1 0 0 1 1 1 1 GlcNAc-PI de-N-acetylase UPF0239 PF06783.11 KFX95980.1 - 0.0074 16.4 0.6 0.022 14.9 0.0 1.8 1 1 1 2 2 2 1 Uncharacterised protein family (UPF0239) Epiglycanin_C PF14654.6 KFX95980.1 - 0.38 10.8 1.3 0.69 10.0 1.3 1.4 1 0 0 1 1 1 0 Mucin, catalytic, TM and cytoplasmic tail region APP_E2 PF12925.7 KFX95981.1 - 0.13 11.9 0.0 0.18 11.5 0.0 1.1 1 0 0 1 1 1 0 E2 domain of amyloid precursor protein Peptidase_S8 PF00082.22 KFX95992.1 - 7.7e-07 28.7 1.5 7.7e-07 28.7 1.5 1.1 1 0 0 1 1 1 1 Subtilase family LexA_DNA_bind PF01726.16 KFX95992.1 - 0.0093 15.7 0.0 0.01 15.6 0.0 1.2 1 0 0 1 1 1 1 LexA DNA binding domain Transferase PF02458.15 KFX95994.1 - 1.1e-21 77.0 0.0 4.9e-21 74.9 0.0 1.8 1 1 0 1 1 1 1 Transferase family Transferase PF02458.15 KFX95995.1 - 2.3e-14 52.9 0.0 1.7e-13 50.0 0.0 2.2 1 1 0 1 1 1 1 Transferase family DUF2293 PF10056.9 KFX96017.1 - 6.9e-31 106.3 0.1 1.4e-30 105.3 0.1 1.6 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2293) AAA PF00004.29 KFX96018.1 - 5e-47 159.6 0.0 6.7e-47 159.2 0.0 1.2 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KFX96018.1 - 9.3e-09 35.0 0.4 1.9e-08 34.0 0.4 1.5 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 KFX96018.1 - 1.5e-07 32.0 0.1 8e-05 23.1 0.0 2.5 2 1 1 3 3 2 1 AAA ATPase domain RuvB_N PF05496.12 KFX96018.1 - 2e-06 27.6 0.0 6.2e-06 26.0 0.0 1.8 1 1 1 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 KFX96018.1 - 6.3e-05 23.3 0.0 0.0073 16.6 0.0 2.4 2 1 1 3 3 2 1 AAA domain AAA_2 PF07724.14 KFX96018.1 - 0.00011 22.3 0.0 0.00019 21.6 0.0 1.3 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 KFX96018.1 - 0.0004 20.4 0.1 0.003 17.6 0.1 2.3 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_33 PF13671.6 KFX96018.1 - 0.0005 20.2 0.0 0.00092 19.4 0.0 1.6 1 1 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 KFX96018.1 - 0.0027 17.1 0.0 0.01 15.2 0.0 1.9 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_14 PF13173.6 KFX96018.1 - 0.0035 17.4 0.0 0.0052 16.8 0.0 1.2 1 0 0 1 1 1 1 AAA domain DUF815 PF05673.13 KFX96018.1 - 0.0042 16.3 0.0 0.006 15.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF815) TIP49 PF06068.13 KFX96018.1 - 0.0048 16.1 0.0 0.0067 15.7 0.0 1.2 1 0 0 1 1 1 1 TIP49 P-loop domain Zeta_toxin PF06414.12 KFX96018.1 - 0.0051 16.1 0.0 0.01 15.2 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin NACHT PF05729.12 KFX96018.1 - 0.0092 15.9 0.1 0.24 11.3 0.0 2.1 1 1 0 2 2 2 1 NACHT domain IstB_IS21 PF01695.17 KFX96018.1 - 0.0096 15.7 0.0 0.016 15.0 0.0 1.3 1 0 0 1 1 1 1 IstB-like ATP binding protein Sigma54_activat PF00158.26 KFX96018.1 - 0.011 15.5 0.0 0.032 13.9 0.0 1.9 1 1 0 1 1 1 0 Sigma-54 interaction domain RNA_helicase PF00910.22 KFX96018.1 - 0.014 15.7 0.0 0.024 15.0 0.0 1.4 1 0 0 1 1 1 0 RNA helicase AAA_3 PF07726.11 KFX96018.1 - 0.015 15.1 0.0 0.026 14.4 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) ABC_tran PF00005.27 KFX96018.1 - 0.016 15.7 0.0 0.024 15.1 0.0 1.4 1 0 0 1 1 1 0 ABC transporter AAA_18 PF13238.6 KFX96018.1 - 0.021 15.4 0.0 0.038 14.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 KFX96018.1 - 0.026 14.8 0.0 0.065 13.5 0.0 1.8 2 0 0 2 2 2 0 AAA domain Sigma54_activ_2 PF14532.6 KFX96018.1 - 0.042 14.0 0.0 0.07 13.3 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain Rad17 PF03215.15 KFX96018.1 - 0.044 13.7 0.0 0.065 13.1 0.0 1.2 1 0 0 1 1 1 0 Rad17 P-loop domain ATPase_2 PF01637.18 KFX96018.1 - 0.045 13.7 0.0 0.45 10.4 0.0 1.9 1 1 1 2 2 2 0 ATPase domain predominantly from Archaea Viral_helicase1 PF01443.18 KFX96018.1 - 0.046 13.4 0.0 0.064 13.0 0.0 1.2 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase TsaE PF02367.17 KFX96018.1 - 0.057 13.4 0.0 0.093 12.7 0.0 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_25 PF13481.6 KFX96018.1 - 0.061 12.9 0.0 0.8 9.3 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 KFX96018.1 - 0.08 12.4 0.0 0.16 11.5 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region Cytidylate_kin2 PF13189.6 KFX96018.1 - 0.095 12.8 0.0 0.16 12.1 0.0 1.3 1 0 0 1 1 1 0 Cytidylate kinase-like family AAA_24 PF13479.6 KFX96018.1 - 0.11 12.2 0.0 0.15 11.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.22 KFX96018.1 - 0.13 11.4 0.0 0.2 10.8 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain AAA_11 PF13086.6 KFX96018.1 - 0.17 11.7 0.0 0.25 11.1 0.0 1.2 1 0 0 1 1 1 0 AAA domain Parvo_NS1 PF01057.17 KFX96018.1 - 0.28 10.2 0.0 0.42 9.7 0.0 1.1 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 NmrA PF05368.13 KFX96024.1 - 0.011 15.3 0.0 0.015 14.9 0.0 1.1 1 0 0 1 1 1 0 NmrA-like family Band_7 PF01145.25 KFX96025.1 - 1.9e-24 86.6 6.9 3.9e-24 85.6 6.9 1.5 1 1 0 1 1 1 1 SPFH domain / Band 7 family YdfA_immunity PF12127.8 KFX96025.1 - 0.00019 20.6 4.0 0.00025 20.2 4.0 1.2 1 0 0 1 1 1 1 SigmaW regulon antibacterial UcrQ PF02939.16 KFX96026.1 - 3.7e-36 122.9 0.5 4.3e-36 122.7 0.5 1.1 1 0 0 1 1 1 1 UcrQ family Nucleopor_Nup85 PF07575.13 KFX96027.1 - 2.3e-20 72.7 0.1 1.8e-13 50.0 0.0 3.1 3 0 0 3 3 3 3 Nup85 Nucleoporin Smg4_UPF3 PF03467.15 KFX96029.1 - 1e-43 149.3 0.0 1e-43 149.3 0.0 2.1 2 0 0 2 2 2 1 Smg-4/UPF3 family Metallophos PF00149.28 KFX96030.1 - 7.1e-33 114.8 0.0 1.9e-28 100.4 0.0 2.2 2 0 0 2 2 2 2 Calcineurin-like phosphoesterase Glyco_hydro_65N PF03636.15 KFX96030.1 - 0.03 14.0 0.0 0.046 13.4 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 65, N-terminal domain RIBIOP_C PF04950.12 KFX96033.1 - 1e-111 373.1 0.0 1.5e-111 372.5 0.0 1.3 1 0 0 1 1 1 1 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal AARP2CN PF08142.12 KFX96033.1 - 1.8e-16 60.0 0.0 6e-16 58.3 0.0 1.9 1 0 0 1 1 1 1 AARP2CN (NUC121) domain FA_desaturase PF00487.24 KFX96034.1 - 1.3e-26 94.0 12.3 1.9e-26 93.5 12.3 1.2 1 0 0 1 1 1 1 Fatty acid desaturase Lipid_DES PF08557.10 KFX96034.1 - 2e-17 62.4 0.7 3.8e-17 61.5 0.7 1.5 1 0 0 1 1 1 1 Sphingolipid Delta4-desaturase (DES) Motile_Sperm PF00635.26 KFX96035.1 - 3.8e-25 87.9 0.2 7.2e-25 87.0 0.1 1.5 1 1 0 1 1 1 1 MSP (Major sperm protein) domain ASH PF15780.5 KFX96035.1 - 0.01 16.0 0.0 0.02 15.1 0.0 1.4 1 0 0 1 1 1 0 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin UBX PF00789.20 KFX96036.1 - 1.3e-06 28.5 0.0 4.3e-06 26.9 0.0 1.9 1 0 0 1 1 1 1 UBX domain UBA PF00627.31 KFX96036.1 - 0.0012 18.7 0.0 0.0026 17.6 0.0 1.6 1 0 0 1 1 1 1 UBA/TS-N domain FmrO PF07091.11 KFX96036.1 - 0.012 15.2 0.2 0.02 14.4 0.2 1.4 1 0 0 1 1 1 0 Ribosomal RNA methyltransferase (FmrO) zf-C2H2_2 PF12756.7 KFX96036.1 - 0.02 15.2 0.1 0.044 14.1 0.1 1.5 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) zf_UBZ PF18439.1 KFX96036.1 - 0.31 10.7 1.7 5.7 6.6 1.7 2.3 1 1 0 1 1 1 0 Ubiquitin-Binding Zinc Finger Hamartin PF04388.12 KFX96036.1 - 2.4 6.7 17.1 3 6.4 17.1 1.0 1 0 0 1 1 1 0 Hamartin protein CpXC PF14353.6 KFX96036.1 - 9.8 6.2 8.1 38 4.3 8.1 2.1 1 1 0 1 1 1 0 CpXC protein DUF3723 PF12520.8 KFX96040.1 - 1.2e-108 364.0 0.9 2.4e-106 356.4 0.9 2.2 1 1 0 1 1 1 1 Protein of unknown function (DUF3723) Pkinase_Tyr PF07714.17 KFX96041.1 - 2.6e-05 23.6 0.0 4.1e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KFX96041.1 - 3.3e-05 23.4 0.0 7.9e-05 22.2 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain F-box-like PF12937.7 KFX96043.1 - 0.002 18.0 0.0 0.0048 16.8 0.0 1.7 1 0 0 1 1 1 1 F-box-like Bactofilin PF04519.13 KFX96043.1 - 0.083 13.2 3.4 1.3 9.4 0.9 2.4 1 1 1 2 2 2 0 Polymer-forming cytoskeletal DUF4164 PF13747.6 KFX96045.1 - 0.0097 16.2 0.3 0.024 14.9 0.3 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4164) Pkinase PF00069.25 KFX96046.1 - 3.3e-10 39.8 0.1 5.7e-10 39.0 0.1 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFX96046.1 - 7.5e-06 25.4 0.1 1.2e-05 24.7 0.1 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase TPR_2 PF07719.17 KFX96047.1 - 0.0094 16.0 2.0 0.4 10.9 0.0 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.6 KFX96047.1 - 0.021 15.6 0.0 21 6.3 0.0 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_8 PF13181.6 KFX96047.1 - 0.043 14.0 0.0 0.22 11.8 0.0 2.3 1 0 0 1 1 1 0 Tetratricopeptide repeat Acetyltransf_1 PF00583.25 KFX96048.1 - 0.018 15.3 0.0 0.042 14.1 0.0 1.6 2 0 0 2 2 2 0 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KFX96048.1 - 0.039 14.4 0.0 0.073 13.5 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KFX96048.1 - 0.15 12.0 0.0 0.28 11.1 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_13 PF13880.6 KFX96048.1 - 0.16 11.9 0.0 0.35 10.9 0.0 1.5 1 1 0 1 1 1 0 ESCO1/2 acetyl-transferase Glyco_hyd_65N_2 PF14498.6 KFX96066.1 - 7.6e-53 179.8 0.0 1.2e-52 179.2 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 65, N-terminal domain Pox_EPC_I2-L1 PF12575.8 KFX96067.1 - 0.088 13.0 0.2 0.13 12.5 0.2 1.2 1 0 0 1 1 1 0 Poxvirus entry protein complex L1 and I2 DUF2418 PF10332.9 KFX96067.1 - 0.15 12.6 0.3 0.26 11.8 0.0 1.6 2 1 0 2 2 2 0 Protein of unknown function (DUF2418) Pyridoxal_deC PF00282.19 KFX96068.1 - 8.6e-14 51.0 0.0 1.4e-13 50.3 0.0 1.3 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.19 KFX96068.1 - 0.0048 15.9 0.0 0.0083 15.1 0.0 1.4 1 1 0 1 1 1 1 Aminotransferase class-V Glyco_transf_34 PF05637.12 KFX96069.1 - 2e-73 247.0 0.0 2.5e-73 246.7 0.0 1.0 1 0 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family SSV1_ORF_D-335 PF07935.11 KFX96069.1 - 0.15 12.4 0.0 8.2 6.8 0.0 2.5 2 0 0 2 2 2 0 ORF D-335-like protein PMI_typeI PF01238.21 KFX96070.1 - 8.4e-66 222.7 0.0 6.5e-65 219.7 0.0 1.9 1 1 0 1 1 1 1 Phosphomannose isomerase type I Cupin_2 PF07883.11 KFX96070.1 - 0.0026 17.4 0.2 2 8.2 0.3 2.6 2 0 0 2 2 2 2 Cupin domain AraC_binding PF02311.19 KFX96070.1 - 0.18 11.7 0.1 0.75 9.7 0.0 1.9 2 0 0 2 2 2 0 AraC-like ligand binding domain AMP-binding PF00501.28 KFX96072.1 - 1.1e-88 297.7 0.0 1.3e-88 297.4 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KFX96072.1 - 2.3e-17 63.8 0.0 5.8e-17 62.5 0.0 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain GH3 PF03321.13 KFX96072.1 - 0.00024 20.1 0.0 0.0009 18.2 0.0 1.8 2 0 0 2 2 2 1 GH3 auxin-responsive promoter RTX_C PF08339.10 KFX96072.1 - 0.087 12.9 0.0 0.2 11.7 0.0 1.5 1 0 0 1 1 1 0 RTX C-terminal domain NAD_binding_2 PF03446.15 KFX96073.1 - 7.1e-26 91.3 0.0 1.3e-25 90.4 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 KFX96073.1 - 7.5e-10 39.1 0.1 1.4e-09 38.2 0.1 1.4 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase F420_oxidored PF03807.17 KFX96073.1 - 1.6e-07 31.8 0.0 4.2e-07 30.5 0.0 1.7 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Shikimate_DH PF01488.20 KFX96073.1 - 1.1e-06 28.8 0.0 3.7e-06 27.0 0.0 1.9 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase Sacchrp_dh_NADP PF03435.18 KFX96073.1 - 0.08 13.2 0.0 0.18 12.1 0.0 1.6 1 1 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Glyco_hydro_61 PF03443.14 KFX96074.1 - 5.4e-59 199.6 0.0 8.2e-59 199.0 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Sugar_tr PF00083.24 KFX96075.1 - 6.2e-78 262.7 15.3 7.8e-78 262.3 15.3 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KFX96075.1 - 4.6e-18 65.3 23.2 4.6e-18 65.3 23.2 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Zn_clus PF00172.18 KFX96076.1 - 9.2e-09 35.3 8.4 1.6e-08 34.5 8.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KFX96076.1 - 0.064 12.3 0.1 0.14 11.1 0.1 1.6 1 0 0 1 1 1 0 Fungal specific transcription factor domain Glyco_hydro_3_C PF01915.22 KFX96077.1 - 3.1e-64 216.7 0.0 7.4e-64 215.5 0.0 1.7 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 KFX96077.1 - 1.2e-50 172.7 0.0 2e-50 172.0 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 KFX96077.1 - 6.3e-21 74.3 0.9 1.5e-20 73.1 0.6 1.8 2 0 0 2 2 2 1 Fibronectin type III-like domain PA14 PF07691.12 KFX96077.1 - 2.1e-15 56.8 0.1 4e-15 55.9 0.1 1.4 1 0 0 1 1 1 1 PA14 domain CARDB PF07705.11 KFX96077.1 - 0.024 14.9 0.3 0.62 10.4 0.1 2.4 2 0 0 2 2 2 0 CARDB Pkinase PF00069.25 KFX96078.1 - 8.1e-66 222.1 0.5 1e-65 221.8 0.5 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFX96078.1 - 1.6e-20 73.5 0.0 2.4e-20 72.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KFX96078.1 - 3.1e-07 30.6 0.0 5.2e-05 23.3 0.2 2.6 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.6 KFX96078.1 - 0.0011 18.3 0.0 0.0021 17.4 0.0 1.4 1 1 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 KFX96078.1 - 0.0029 16.4 0.0 0.0059 15.4 0.0 1.4 2 0 0 2 2 2 1 Fungal protein kinase Kdo PF06293.14 KFX96078.1 - 0.016 14.6 0.3 0.044 13.1 0.3 1.7 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 KFX96078.1 - 0.073 12.6 0.1 0.073 12.6 0.1 2.2 3 0 0 3 3 3 0 Choline/ethanolamine kinase RNase_P_p30 PF01876.16 KFX96079.1 - 2.5e-58 197.1 0.0 4e-58 196.4 0.0 1.3 1 0 0 1 1 1 1 RNase P subunit p30 TFIIS_M PF07500.14 KFX96081.1 - 2e-28 99.1 0.7 4.2e-28 98.1 0.7 1.6 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS), central domain TFIIS_C PF01096.18 KFX96081.1 - 3.9e-18 65.0 6.1 6.2e-18 64.4 6.1 1.3 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS) Med26 PF08711.11 KFX96081.1 - 8.3e-10 38.5 0.6 2.4e-09 37.1 0.6 1.8 1 0 0 1 1 1 1 TFIIS helical bundle-like domain Arteri_nsp7a PF16749.5 KFX96081.1 - 0.035 14.3 0.2 1.2 9.3 0.0 2.7 2 1 0 2 2 2 0 Arterivirus nonstructural protein 7 alpha PALP PF00291.25 KFX96082.1 - 1e-58 199.1 0.8 1.2e-58 198.9 0.8 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Methyltransf_28 PF02636.17 KFX96083.1 - 3.6e-42 144.8 0.0 5.4e-42 144.2 0.0 1.2 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase PRMT5 PF05185.16 KFX96083.1 - 8.2e-05 22.5 0.2 0.00023 21.1 0.2 1.8 1 1 0 1 1 1 1 PRMT5 arginine-N-methyltransferase GrpB PF04229.14 KFX96084.1 - 1.6e-37 129.2 0.1 1.8e-37 129.0 0.1 1.1 1 0 0 1 1 1 1 GrpB protein NTP_transf_5 PF14907.6 KFX96084.1 - 0.037 13.6 0.0 0.045 13.4 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised nucleotidyltransferase tRNA-synt_2c PF01411.19 KFX96085.1 - 4e-187 623.1 1.0 4e-187 623.1 1.0 1.6 2 0 0 2 2 2 1 tRNA synthetases class II (A) tRNA_SAD PF07973.14 KFX96085.1 - 1e-17 63.9 0.4 2.2e-17 62.9 0.4 1.6 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain DHHA1 PF02272.19 KFX96085.1 - 4.7e-13 49.7 2.1 1.1e-12 48.6 2.1 1.7 1 0 0 1 1 1 1 DHHA1 domain PdaC PF13739.6 KFX96085.1 - 0.94 10.5 4.9 5.2 8.1 4.0 2.8 3 0 0 3 3 3 0 Deacetylase PdaC Pro_isomerase PF00160.21 KFX96089.1 - 1.6e-41 142.2 0.4 2.1e-41 141.8 0.4 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD adh_short PF00106.25 KFX96090.1 - 9.8e-33 113.2 0.4 1.2e-32 112.9 0.4 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KFX96090.1 - 7.3e-23 81.3 0.5 1.1e-22 80.7 0.5 1.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KFX96090.1 - 6.2e-13 49.1 0.1 8.7e-13 48.6 0.1 1.1 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 KFX96090.1 - 4.7e-05 22.7 0.0 5.7e-05 22.4 0.0 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Epimerase PF01370.21 KFX96090.1 - 0.0053 16.2 0.4 0.015 14.7 0.4 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family ThiF PF00899.21 KFX96090.1 - 0.38 10.1 1.5 16 4.7 0.1 2.4 2 1 0 2 2 2 0 ThiF family Pro_isomerase PF00160.21 KFX96091.1 - 5.3e-49 166.5 0.0 1e-48 165.6 0.0 1.5 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD U-box PF04564.15 KFX96091.1 - 0.00023 21.3 0.1 0.00066 19.8 0.0 1.7 2 0 0 2 2 2 1 U-box domain zf-NOSIP PF15906.5 KFX96091.1 - 0.005 17.0 0.0 0.013 15.6 0.0 1.7 1 0 0 1 1 1 1 Zinc-finger of nitric oxide synthase-interacting protein Tetrabrachion PF11401.8 KFX96091.1 - 0.15 12.1 0.3 6.5 6.8 0.0 2.4 2 0 0 2 2 2 0 Tetrabrachion YjeF_N PF03853.15 KFX96092.1 - 2.6e-34 118.6 0.0 3.3e-34 118.2 0.0 1.1 1 0 0 1 1 1 1 YjeF-related protein N-terminus Fungal_trans_2 PF11951.8 KFX96093.1 - 1.3e-08 34.1 0.2 1.9e-08 33.5 0.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn-C2H2_12 PF18112.1 KFX96093.1 - 0.049 14.1 0.2 0.1 13.1 0.2 1.5 1 0 0 1 1 1 0 Autophagy receptor zinc finger-C2H2 domain HMGL-like PF00682.19 KFX96096.1 - 7.5e-68 228.9 0.2 1.2e-67 228.3 0.2 1.3 1 0 0 1 1 1 1 HMGL-like DAO PF01266.24 KFX96098.1 - 8.6e-43 147.3 0.0 1.1e-42 146.9 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 KFX96098.1 - 0.0001 22.3 0.0 0.034 14.2 0.0 2.3 2 0 0 2 2 2 2 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 KFX96098.1 - 0.012 15.8 0.1 0.025 14.8 0.1 1.5 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KFX96098.1 - 0.19 10.9 0.0 0.37 10.0 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase PNRC PF15365.6 KFX96098.1 - 0.2 11.5 2.5 0.42 10.5 2.5 1.6 1 0 0 1 1 1 0 Proline-rich nuclear receptor coactivator motif adh_short PF00106.25 KFX96099.1 - 1.8e-20 73.2 0.0 1.3e-18 67.2 0.0 2.2 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 KFX96099.1 - 3.6e-14 52.9 0.0 7.5e-14 51.8 0.0 1.5 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.6 KFX96099.1 - 9.2e-14 51.7 0.0 8.3e-12 45.4 0.0 2.3 2 0 0 2 2 2 1 NAD(P)H-binding NmrA PF05368.13 KFX96099.1 - 4.8e-10 39.4 0.0 2.8e-09 36.9 0.0 2.0 2 0 0 2 2 2 1 NmrA-like family KR PF08659.10 KFX96099.1 - 7.1e-09 35.8 0.0 0.00029 20.8 0.0 2.3 2 0 0 2 2 2 2 KR domain Epimerase PF01370.21 KFX96099.1 - 2.1e-08 33.9 0.0 0.0032 17.0 0.0 2.4 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KFX96099.1 - 0.00019 21.0 0.0 0.3 10.4 0.0 2.2 2 0 0 2 2 2 2 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 KFX96099.1 - 0.00031 19.9 0.1 0.00086 18.4 0.0 1.8 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 KFX96099.1 - 0.0006 19.0 0.0 0.079 12.0 0.0 2.3 2 0 0 2 2 2 2 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 KFX96099.1 - 0.0006 19.0 0.0 0.47 9.5 0.0 2.9 3 0 0 3 3 3 2 Polysaccharide biosynthesis protein DapB_N PF01113.20 KFX96099.1 - 0.001 19.2 0.0 0.0035 17.5 0.0 1.9 2 0 0 2 2 2 1 Dihydrodipicolinate reductase, N-terminus NAD_binding_4 PF07993.12 KFX96099.1 - 0.0039 16.4 0.0 0.073 12.2 0.0 2.6 2 1 0 2 2 2 1 Male sterility protein Semialdhyde_dh PF01118.24 KFX96099.1 - 0.0068 16.8 0.0 0.016 15.6 0.0 1.7 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain zf-C2H2 PF00096.26 KFX96119.1 - 1.6e-06 28.2 13.3 0.044 14.3 2.4 3.7 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KFX96119.1 - 0.0018 18.6 10.4 0.63 10.6 0.2 3.9 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 KFX96119.1 - 0.0066 17.2 11.8 0.062 14.2 1.8 3.6 3 0 0 3 3 3 2 C2H2-type zinc finger zf-Di19 PF05605.12 KFX96119.1 - 0.047 14.0 6.7 0.17 12.2 0.8 2.4 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding Nuc_sug_transp PF04142.15 KFX96120.1 - 1.5e-06 27.6 3.1 2.5e-06 26.9 3.1 1.3 1 0 0 1 1 1 1 Nucleotide-sugar transporter EamA PF00892.20 KFX96120.1 - 3.1e-06 27.4 22.2 0.0061 16.7 5.3 2.5 2 1 0 2 2 2 2 EamA-like transporter family Internalin_N PF12354.8 KFX96120.1 - 0.17 12.0 0.3 0.74 9.9 0.0 2.4 2 0 0 2 2 2 0 Bacterial adhesion/invasion protein N terminal Imp-YgjV PF10688.9 KFX96120.1 - 2 8.2 14.1 1.6 8.5 1.4 2.6 2 0 0 2 2 2 0 Bacterial inner membrane protein DUF2985 PF11204.8 KFX96121.1 - 1.7e-40 137.0 1.2 3.7e-40 136.0 1.2 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2985) KAR9 PF08580.10 KFX96121.1 - 5.1 5.5 8.3 1 7.8 4.8 1.4 1 1 0 1 1 1 0 Yeast cortical protein KAR9 Sen15 PF09631.10 KFX96122.1 - 7.9e-25 87.1 0.0 1.4e-24 86.3 0.0 1.4 1 0 0 1 1 1 1 Sen15 protein ADH_N PF08240.12 KFX96123.1 - 1.7e-29 101.9 0.4 2.8e-29 101.2 0.4 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KFX96123.1 - 3.7e-21 75.5 0.0 6e-21 74.8 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 KFX96123.1 - 3.7e-05 23.3 0.0 6e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus AlaDh_PNT_C PF01262.21 KFX96123.1 - 8.2e-05 22.0 0.1 0.00015 21.1 0.1 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain ADH_zinc_N_2 PF13602.6 KFX96123.1 - 0.0003 21.8 0.0 0.00053 21.0 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_assoc PF13823.6 KFX96123.1 - 0.0036 17.2 0.1 0.0081 16.1 0.1 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-associated 2-Hacid_dh_C PF02826.19 KFX96123.1 - 0.14 11.5 0.0 0.23 10.8 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Yippee-Mis18 PF03226.14 KFX96124.1 - 4.6e-17 62.1 0.8 5.2e-17 62.0 0.8 1.1 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly RIG-I_C-RD PF11648.8 KFX96124.1 - 0.062 13.5 1.1 0.094 12.9 1.1 1.3 1 1 0 1 1 1 0 C-terminal domain of RIG-I RNA_POL_M_15KD PF02150.16 KFX96124.1 - 0.12 12.3 1.1 3.2 7.7 0.1 2.3 2 0 0 2 2 2 0 RNA polymerases M/15 Kd subunit DiS_P_DiS PF06750.13 KFX96124.1 - 0.4 10.8 1.7 20 5.4 0.1 2.2 1 1 2 3 3 3 0 Bacterial Peptidase A24 N-terminal domain Ferric_reduct PF01794.19 KFX96126.1 - 1.2e-23 83.6 13.4 2.4e-22 79.4 10.1 2.7 2 0 0 2 2 2 2 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 KFX96126.1 - 1.8e-19 70.4 0.0 5.7e-11 42.8 0.0 2.5 1 1 1 2 2 2 2 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 KFX96126.1 - 2.1e-11 43.9 0.0 9.8e-07 28.8 0.0 2.3 2 0 0 2 2 2 2 FAD-binding domain Baculo_11_kDa PF06143.11 KFX96126.1 - 0.0054 16.3 0.1 0.015 14.8 0.1 1.8 1 0 0 1 1 1 1 Baculovirus 11 kDa family SH3_3 PF08239.11 KFX96132.1 - 0.00017 21.8 0.3 0.00032 20.9 0.1 1.5 2 0 0 2 2 2 1 Bacterial SH3 domain Response_reg PF00072.24 KFX96135.1 - 1.3e-25 89.7 0.3 2.3e-25 88.9 0.3 1.4 1 0 0 1 1 1 1 Response regulator receiver domain HATPase_c PF02518.26 KFX96135.1 - 4e-25 88.5 1.5 9.3e-19 68.0 0.0 3.3 3 0 0 3 3 3 2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 KFX96135.1 - 2.3e-14 53.2 0.0 5.5e-14 51.9 0.0 1.7 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain HAMP PF00672.25 KFX96135.1 - 0.011 16.1 0.2 0.083 13.3 0.2 2.3 2 0 0 2 2 2 0 HAMP domain CorA PF01544.18 KFX96135.1 - 0.15 11.4 0.4 0.31 10.3 0.4 1.4 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein Exo_endo_phos PF03372.23 KFX96136.1 - 0.0024 17.4 0.0 0.0048 16.4 0.0 1.8 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.6 KFX96136.1 - 0.033 14.0 0.0 0.077 12.8 0.0 1.6 1 0 0 1 1 1 0 Endonuclease-reverse transcriptase Syja_N PF02383.18 KFX96137.1 - 9.5e-94 314.3 0.0 1.4e-93 313.7 0.0 1.3 1 0 0 1 1 1 1 SacI homology domain hSac2 PF12456.8 KFX96137.1 - 1.1e-35 121.8 0.0 2e-35 120.9 0.0 1.4 1 0 0 1 1 1 1 Inositol phosphatase Methyltransf_34 PF11312.8 KFX96138.1 - 1.2e-100 336.7 0.0 1.4e-100 336.5 0.0 1.0 1 0 0 1 1 1 1 Putative SAM-dependent methyltransferase zf-C2H2 PF00096.26 KFX96139.1 - 5.2e-05 23.5 13.9 0.26 11.8 4.1 3.6 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_aberr PF17017.5 KFX96139.1 - 5.3e-05 23.4 0.1 0.00037 20.7 0.0 2.2 2 1 0 2 2 2 1 Aberrant zinc-finger APG6_N PF17675.1 KFX96139.1 - 0.0016 19.0 12.9 0.0033 17.9 12.9 1.5 1 0 0 1 1 1 1 Apg6 coiled-coil region zf-C2H2_4 PF13894.6 KFX96139.1 - 0.016 16.0 9.2 13 6.9 3.2 3.8 3 0 0 3 3 3 0 C2H2-type zinc finger FOXP-CC PF16159.5 KFX96139.1 - 0.07 13.8 1.9 0.07 13.8 1.9 4.2 2 1 2 4 4 3 0 FOXP coiled-coil domain SKA2 PF16740.5 KFX96139.1 - 0.64 9.8 10.4 1.5 8.7 10.4 1.5 1 0 0 1 1 1 0 Spindle and kinetochore-associated protein 2 V_ATPase_I PF01496.19 KFX96139.1 - 0.78 7.6 9.2 0.96 7.3 9.2 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF3782 PF12644.7 KFX96139.1 - 0.87 9.8 5.1 1.2 9.3 4.3 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3782) UPF0242 PF06785.11 KFX96139.1 - 2.6 8.1 10.5 4.3 7.4 10.5 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus XhlA PF10779.9 KFX96139.1 - 3.7 7.8 4.6 8 6.8 4.6 1.6 1 0 0 1 1 1 0 Haemolysin XhlA TMPIT PF07851.13 KFX96139.1 - 9.4 5.4 8.0 14 4.8 8.0 1.2 1 0 0 1 1 1 0 TMPIT-like protein LRR_6 PF13516.6 KFX96143.1 - 0.00062 19.6 0.2 6.6 7.1 0.0 4.2 3 0 0 3 3 3 2 Leucine Rich repeat LRR_8 PF13855.6 KFX96143.1 - 0.075 12.8 1.4 0.87 9.4 0.1 2.9 2 0 0 2 2 2 0 Leucine rich repeat Cyt_bd_oxida_I PF01654.17 KFX96143.1 - 0.18 10.4 0.3 0.26 9.8 0.3 1.1 1 0 0 1 1 1 0 Cytochrome bd terminal oxidase subunit I LRR_1 PF00560.33 KFX96143.1 - 0.35 11.6 1.4 12 6.9 0.1 3.9 4 0 0 4 4 4 0 Leucine Rich Repeat LRR_4 PF12799.7 KFX96143.1 - 0.49 10.9 8.0 0.56 10.7 0.1 4.4 4 2 2 6 6 6 0 Leucine Rich repeats (2 copies) MFS_1 PF07690.16 KFX96147.1 - 7.6e-14 51.4 39.0 2.5e-13 49.7 39.0 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily Adeno_E3_CR2 PF02439.15 KFX96148.1 - 0.00052 19.7 0.3 0.00098 18.8 0.3 1.4 1 0 0 1 1 1 1 Adenovirus E3 region protein CR2 Asp PF00026.23 KFX96148.1 - 0.0013 18.2 0.0 1.2 8.5 0.0 2.3 2 1 0 2 2 2 2 Eukaryotic aspartyl protease TMEM154 PF15102.6 KFX96149.1 - 0.073 13.0 0.0 0.17 11.8 0.0 1.5 2 0 0 2 2 2 0 TMEM154 protein family TMEM132D_C PF15706.5 KFX96149.1 - 0.085 12.6 0.0 0.18 11.6 0.0 1.5 1 0 0 1 1 1 0 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term TFIIA PF03153.13 KFX96149.1 - 0.32 11.0 11.7 0.45 10.4 11.7 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit zf-C2H2_2 PF12756.7 KFX96150.1 - 5.9e-32 110.0 8.9 2.5e-23 82.3 3.0 3.5 3 0 0 3 3 3 3 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.8 KFX96150.1 - 9.9e-07 28.9 8.2 4.3e-05 23.7 0.3 3.1 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding F-box-like PF12937.7 KFX96150.1 - 0.003 17.4 0.5 0.0087 15.9 0.5 1.9 1 1 0 1 1 1 1 F-box-like zf-met PF12874.7 KFX96150.1 - 0.003 17.9 8.5 0.37 11.2 0.9 3.3 3 0 0 3 3 3 2 Zinc-finger of C2H2 type zf-TFIIIC PF12660.7 KFX96150.1 - 0.0036 17.2 0.0 0.017 15.0 0.0 2.1 1 1 0 1 1 1 1 Putative zinc-finger of transcription factor IIIC complex DUF2256 PF10013.9 KFX96150.1 - 0.025 14.7 0.4 0.86 9.8 0.0 2.8 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2256) zf-C2H2_4 PF13894.6 KFX96150.1 - 0.24 12.4 16.0 0.52 11.3 0.2 4.6 4 0 0 4 4 4 0 C2H2-type zinc finger zf-C2H2 PF00096.26 KFX96150.1 - 3.3 8.4 14.1 2.1 9.0 1.2 4.3 3 0 0 3 3 3 0 Zinc finger, C2H2 type zf-LYAR PF08790.11 KFX96150.1 - 5.5 7.0 5.7 28 4.7 1.0 2.9 3 0 0 3 3 3 0 LYAR-type C2HC zinc finger CAP_N PF01213.19 KFX96151.1 - 0.04 13.4 0.6 0.044 13.3 0.6 1.1 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Beta_helix PF13229.6 KFX96153.1 - 1.8e-12 47.4 16.1 2e-07 31.0 6.4 3.0 2 1 0 2 2 2 2 Right handed beta helix region DUF1565 PF07602.11 KFX96153.1 - 0.31 10.3 8.7 0.31 10.4 1.6 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF1565) Sulfatase PF00884.23 KFX96154.1 - 6.3e-44 150.6 0.2 2.2e-41 142.3 0.0 2.6 2 1 0 2 2 2 1 Sulfatase Phosphodiest PF01663.22 KFX96154.1 - 1.7e-06 27.9 0.2 3.9e-05 23.4 0.2 2.4 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase DUF4976 PF16347.5 KFX96154.1 - 1.4e-05 25.3 1.4 1.4e-05 25.3 1.4 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF4976) Sulfatase_C PF14707.6 KFX96154.1 - 0.02 15.6 0.0 0.042 14.6 0.0 1.5 1 0 0 1 1 1 0 C-terminal region of aryl-sulfatase An_peroxidase PF03098.15 KFX96154.1 - 0.12 10.9 0.0 0.21 10.1 0.0 1.3 1 0 0 1 1 1 0 Animal haem peroxidase DUF4994 PF16385.5 KFX96154.1 - 0.17 11.8 0.2 0.43 10.5 0.2 1.7 1 0 0 1 1 1 0 Domain of unknown function Sugar_tr PF00083.24 KFX96155.1 - 1.8e-98 330.4 28.7 2.3e-98 330.0 28.7 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KFX96155.1 - 8.6e-25 87.4 21.0 8.6e-25 87.4 21.0 2.2 1 1 1 2 2 2 1 Major Facilitator Superfamily MFS_3 PF05977.13 KFX96155.1 - 0.023 13.1 10.5 0.034 12.5 5.1 2.2 2 0 0 2 2 2 0 Transmembrane secretion effector Fungal_trans PF04082.18 KFX96156.1 - 7.4e-14 51.4 0.1 1.1e-13 50.8 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KFX96156.1 - 0.027 14.6 3.8 0.062 13.4 3.8 1.6 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Glyco_hydro_43 PF04616.14 KFX96157.1 - 6.3e-31 107.7 0.5 9.8e-31 107.1 0.5 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 GMC_oxred_C PF05199.13 KFX96157.1 - 1.2e-29 103.7 0.1 2.4e-29 102.7 0.1 1.5 1 0 0 1 1 1 1 GMC oxidoreductase Chondroitinas_B PF14592.6 KFX96158.1 - 2.5e-07 30.0 0.0 4.2e-07 29.2 0.0 1.3 1 0 0 1 1 1 1 Chondroitinase B Beta_helix PF13229.6 KFX96158.1 - 9e-07 28.9 16.4 8.6e-05 22.4 7.2 2.5 1 1 1 2 2 2 2 Right handed beta helix region Sugar_tr PF00083.24 KFX96159.1 - 6.6e-76 256.0 20.6 8.1e-76 255.7 20.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KFX96159.1 - 1.7e-21 76.5 40.4 4.2e-21 75.3 24.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 KFX96159.1 - 6.8e-06 24.9 15.5 3e-05 22.8 3.9 2.5 2 0 0 2 2 2 2 MFS/sugar transport protein Fungal_trans_2 PF11951.8 KFX96160.1 - 3.6e-49 167.6 1.4 1.3e-30 106.5 0.4 2.3 1 1 1 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.18 KFX96160.1 - 6.3e-08 32.6 5.1 6.3e-08 32.6 5.1 2.1 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain NAD_binding_10 PF13460.6 KFX96161.1 - 2.3e-10 40.7 0.3 1.2e-09 38.3 0.0 2.0 2 0 0 2 2 2 1 NAD(P)H-binding NmrA PF05368.13 KFX96161.1 - 1.4e-06 28.0 0.3 2.8e-06 27.1 0.3 1.7 1 1 0 1 1 1 1 NmrA-like family DapB_N PF01113.20 KFX96161.1 - 0.029 14.5 0.1 0.056 13.6 0.1 1.5 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus KR PF08659.10 KFX96161.1 - 0.049 13.5 0.3 0.09 12.7 0.3 1.6 1 1 0 1 1 1 0 KR domain Antig_Caf1 PF09255.10 KFX96161.1 - 0.064 13.4 0.0 0.16 12.0 0.0 1.6 2 0 0 2 2 2 0 Caf1 Capsule antigen Epimerase PF01370.21 KFX96161.1 - 0.07 12.6 0.3 0.21 11.0 0.1 2.0 2 1 1 3 3 3 0 NAD dependent epimerase/dehydratase family Semialdhyde_dh PF01118.24 KFX96161.1 - 0.078 13.4 0.8 0.3 11.5 0.3 2.2 2 1 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain MANEC PF07502.14 KFX96162.1 - 1.2e-05 25.5 5.2 0.078 13.3 0.0 2.5 2 0 0 2 2 2 2 MANEC domain PAN_4 PF14295.6 KFX96162.1 - 0.021 14.8 1.0 0.021 14.8 1.0 3.4 2 1 0 2 2 2 0 PAN domain Toxin_2 PF00451.19 KFX96162.1 - 4.9 7.5 15.2 11 6.4 0.4 4.1 3 1 1 4 4 4 0 Scorpion short toxin, BmKK2 PAN_3 PF08277.12 KFX96162.1 - 5.3 6.9 11.3 42 4.0 6.5 3.0 2 1 0 2 2 2 0 PAN-like domain NmrA PF05368.13 KFX96163.1 - 8e-29 100.8 0.6 9.5e-29 100.6 0.6 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KFX96163.1 - 2.1e-18 66.9 0.1 6.5e-18 65.3 0.0 1.9 1 1 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KFX96163.1 - 0.00021 20.8 0.1 0.017 14.6 0.0 2.2 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family Semialdhyde_dh PF01118.24 KFX96163.1 - 0.0055 17.1 0.8 0.011 16.2 0.2 1.9 2 1 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain DapB_N PF01113.20 KFX96163.1 - 0.028 14.6 3.1 0.19 11.8 0.3 2.6 2 1 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus Polysacc_synt_2 PF02719.15 KFX96163.1 - 0.073 12.2 0.3 0.38 9.8 0.2 2.0 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein KR PF08659.10 KFX96163.1 - 0.075 12.9 0.1 0.22 11.4 0.0 1.8 2 0 0 2 2 2 0 KR domain PglD_N PF17836.1 KFX96163.1 - 0.14 12.8 0.4 0.41 11.3 0.4 1.9 1 0 0 1 1 1 0 PglD N-terminal domain Fungal_trans PF04082.18 KFX96164.1 - 1.7e-15 56.8 0.2 5.9e-15 55.0 0.0 2.0 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KFX96164.1 - 5.8e-09 35.9 8.6 5.8e-09 35.9 8.6 2.0 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain VWA_2 PF13519.6 KFX96165.1 - 0.00021 21.9 0.0 0.0007 20.2 0.0 1.9 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.28 KFX96165.1 - 0.035 14.4 0.0 0.12 12.7 0.0 1.9 1 1 0 1 1 1 0 von Willebrand factor type A domain adh_short PF00106.25 KFX96166.1 - 4.5e-19 68.7 0.0 6.8e-19 68.1 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KFX96166.1 - 7.1e-12 45.4 0.0 9.2e-12 45.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KFX96166.1 - 3.9e-05 23.6 0.0 0.00067 19.6 0.0 2.3 2 0 0 2 2 2 1 KR domain NAD_binding_10 PF13460.6 KFX96166.1 - 0.065 13.1 0.1 0.17 11.7 0.1 1.9 1 1 0 1 1 1 0 NAD(P)H-binding Fungal_trans_2 PF11951.8 KFX96167.1 - 2.3e-65 220.9 0.7 2.8e-65 220.6 0.7 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain CRM1_repeat_3 PF18787.1 KFX96167.1 - 0.11 12.6 0.1 0.26 11.4 0.1 1.5 1 0 0 1 1 1 0 CRM1 / Exportin repeat 3 SMN PF06003.12 KFX96167.1 - 0.35 10.1 1.4 0.54 9.5 1.4 1.2 1 0 0 1 1 1 0 Survival motor neuron protein (SMN) E3_UbLigase_R4 PF13764.6 KFX96167.1 - 0.85 7.7 5.2 1 7.4 3.4 1.7 2 0 0 2 2 2 0 E3 ubiquitin-protein ligase UBR4 Zn_clus PF00172.18 KFX96168.1 - 0.38 10.9 11.3 5.2 7.3 11.4 2.2 1 1 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain GST_N_3 PF13417.6 KFX96170.1 - 1e-14 54.7 0.0 1.8e-14 53.9 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 KFX96170.1 - 3.3e-12 46.6 0.0 5.8e-12 45.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 KFX96170.1 - 8.8e-11 41.9 0.0 1.4e-10 41.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 KFX96170.1 - 1.8e-09 37.7 0.0 2.8e-09 37.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 KFX96170.1 - 2e-09 37.6 0.0 5.6e-09 36.2 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KFX96170.1 - 8.5e-07 28.9 0.0 1.5e-06 28.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_4 PF17172.4 KFX96170.1 - 0.0076 17.0 0.0 0.016 15.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase N-terminal domain GST_C_5 PF16865.5 KFX96170.1 - 0.022 15.3 0.0 0.13 12.8 0.0 2.0 1 1 1 2 2 2 0 Glutathione S-transferase, C-terminal domain Zn_clus PF00172.18 KFX96171.1 - 1e-06 28.7 11.6 3.6e-06 27.0 11.6 2.0 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Methyltransf_25 PF13649.6 KFX96172.1 - 2.8e-07 31.2 0.0 1.2e-06 29.1 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 KFX96172.1 - 1.3e-05 25.2 0.0 1.8e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KFX96172.1 - 0.0001 22.1 0.2 0.00039 20.2 0.2 1.8 2 0 0 2 2 2 1 Methyltransferase domain PCMT PF01135.19 KFX96172.1 - 0.00056 19.7 0.0 0.00096 19.0 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_12 PF08242.12 KFX96172.1 - 0.00083 20.1 0.0 0.0075 17.0 0.0 2.4 2 1 0 2 2 2 1 Methyltransferase domain MetW PF07021.12 KFX96172.1 - 0.0043 16.7 0.0 0.012 15.2 0.0 1.7 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW GCD14 PF08704.10 KFX96172.1 - 0.0051 16.5 0.0 0.0088 15.7 0.0 1.3 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit Ubie_methyltran PF01209.18 KFX96172.1 - 0.0077 15.6 0.0 0.012 14.9 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family FtsJ PF01728.19 KFX96172.1 - 0.014 15.5 0.0 0.11 12.6 0.0 2.3 1 1 0 2 2 2 0 FtsJ-like methyltransferase Fibrillarin PF01269.17 KFX96172.1 - 0.038 13.1 0.0 0.061 12.4 0.0 1.2 1 0 0 1 1 1 0 Fibrillarin NAD_binding_1 PF00175.21 KFX96174.1 - 5.3e-15 56.0 0.0 7.1e-15 55.6 0.0 1.2 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.12 KFX96174.1 - 1.1e-05 25.6 0.0 1.5e-05 25.1 0.0 1.2 1 0 0 1 1 1 1 Ferric reductase NAD binding domain PEMT PF04191.13 KFX96175.1 - 3.1e-59 197.9 11.1 4.5e-37 126.7 1.9 3.1 3 0 0 3 3 3 2 Phospholipid methyltransferase HECW_N PF16562.5 KFX96175.1 - 0.02 14.7 0.1 0.076 12.8 0.0 1.9 2 0 0 2 2 2 0 N-terminal domain of E3 ubiquitin-protein ligase HECW1 and 2 SKICH PF17751.1 KFX96175.1 - 0.06 13.9 0.0 0.89 10.1 0.0 2.3 1 1 0 1 1 1 0 SKICH domain ParA PF10609.9 KFX96176.1 - 7e-95 317.1 0.0 8.2e-95 316.9 0.0 1.0 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase CbiA PF01656.23 KFX96176.1 - 2e-08 34.3 0.0 7e-08 32.6 0.0 1.9 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.6 KFX96176.1 - 8.9e-05 22.5 0.0 0.00041 20.3 0.0 1.8 1 1 0 1 1 1 1 AAA domain ArsA_ATPase PF02374.15 KFX96176.1 - 0.00059 19.1 0.6 0.0021 17.3 0.3 1.9 1 1 1 2 2 2 1 Anion-transporting ATPase AAA_30 PF13604.6 KFX96176.1 - 0.0048 16.6 0.0 0.0078 15.9 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_26 PF13500.6 KFX96176.1 - 0.0068 16.2 0.1 1.7 8.4 0.0 2.2 2 0 0 2 2 2 1 AAA domain MipZ PF09140.11 KFX96176.1 - 0.0078 15.5 0.0 0.017 14.4 0.0 1.6 1 1 0 1 1 1 1 ATPase MipZ AAA_25 PF13481.6 KFX96176.1 - 0.017 14.7 0.1 0.029 14.0 0.1 1.3 1 0 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 KFX96176.1 - 0.018 15.0 0.0 0.033 14.1 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase Fer4_NifH PF00142.18 KFX96176.1 - 0.019 14.4 0.0 0.73 9.2 0.0 2.2 2 0 0 2 2 2 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family CLP1_P PF16575.5 KFX96176.1 - 0.022 14.6 0.0 0.034 13.9 0.0 1.3 1 0 0 1 1 1 0 mRNA cleavage and polyadenylation factor CLP1 P-loop AAA_16 PF13191.6 KFX96176.1 - 0.026 14.9 0.0 0.044 14.2 0.0 1.4 1 1 0 1 1 1 0 AAA ATPase domain TsaE PF02367.17 KFX96176.1 - 0.075 13.0 0.0 0.13 12.2 0.0 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE RNA_helicase PF00910.22 KFX96176.1 - 0.11 12.9 0.0 0.21 12.0 0.0 1.5 1 0 0 1 1 1 0 RNA helicase SRP54 PF00448.22 KFX96176.1 - 0.11 12.1 0.0 0.25 10.9 0.0 1.7 1 1 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_5 PF07728.14 KFX96176.1 - 0.17 11.8 0.0 0.3 11.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) CBP_BcsQ PF06564.12 KFX96176.1 - 0.25 10.8 0.1 2 7.8 0.1 2.0 1 1 0 1 1 1 0 Cellulose biosynthesis protein BcsQ Rad17 PF03215.15 KFX96176.1 - 0.26 11.2 0.0 0.47 10.3 0.0 1.3 1 0 0 1 1 1 0 Rad17 P-loop domain Zn_clus PF00172.18 KFX96177.1 - 0.00019 21.5 89.3 0.0003 20.9 9.4 9.8 6 3 2 8 8 8 6 Fungal Zn(2)-Cys(6) binuclear cluster domain Myb_Cef PF11831.8 KFX96177.1 - 1.3 8.6 4.2 2 7.9 4.2 1.2 1 0 0 1 1 1 0 pre-mRNA splicing factor component Ras PF00071.22 KFX96178.1 - 2.6e-58 196.2 0.2 3.7e-58 195.7 0.2 1.2 1 0 0 1 1 1 1 Ras family MoCF_biosynth PF00994.24 KFX96178.1 - 8.5e-26 90.3 0.0 4.3e-25 88.1 0.0 2.1 2 0 0 2 2 2 1 Probable molybdopterin binding domain Roc PF08477.13 KFX96178.1 - 8.3e-19 68.0 0.0 1.5e-18 67.2 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFX96178.1 - 1.3e-06 28.0 0.0 2e-06 27.4 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KFX96178.1 - 0.0004 20.0 0.1 0.0015 18.1 0.0 1.8 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 KFX96178.1 - 0.0056 16.6 0.0 2.6 7.9 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 KFX96178.1 - 0.034 14.2 0.0 0.056 13.5 0.0 1.3 1 0 0 1 1 1 0 50S ribosome-binding GTPase CinA_KH PF18146.1 KFX96178.1 - 0.082 13.1 0.0 0.18 12.0 0.0 1.5 1 0 0 1 1 1 0 Damage-inducible protein CinA KH domain NAD_binding_5 PF07994.12 KFX96187.1 - 5.9e-144 479.4 0.1 7.1e-144 479.1 0.1 1.1 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase Inos-1-P_synth PF01658.17 KFX96187.1 - 6.5e-46 155.1 0.7 1.3e-45 154.1 0.3 1.7 2 0 0 2 2 2 1 Myo-inositol-1-phosphate synthase Cupin_2 PF07883.11 KFX96188.1 - 6.3e-08 32.2 0.2 7.9e-08 31.9 0.2 1.1 1 0 0 1 1 1 1 Cupin domain Cupin_1 PF00190.22 KFX96188.1 - 5.5e-05 22.8 0.4 6.6e-05 22.6 0.4 1.1 1 0 0 1 1 1 1 Cupin AraC_binding PF02311.19 KFX96188.1 - 0.011 15.6 0.0 0.012 15.5 0.0 1.1 1 0 0 1 1 1 0 AraC-like ligand binding domain Cwf_Cwc_15 PF04889.12 KFX96189.1 - 3.3e-84 282.5 15.4 4.4e-84 282.1 15.3 1.2 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein SAPS PF04499.15 KFX96189.1 - 0.48 9.2 8.8 0.55 8.9 8.8 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Hid1 PF12722.7 KFX96189.1 - 1.9 6.6 3.9 2.1 6.3 3.9 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein CDC45 PF02724.14 KFX96189.1 - 2.5 6.3 14.4 2.8 6.1 14.4 1.1 1 0 0 1 1 1 0 CDC45-like protein Presenilin PF01080.17 KFX96189.1 - 2.5 6.8 6.7 3.1 6.5 6.7 1.1 1 0 0 1 1 1 0 Presenilin PA26 PF04636.13 KFX96189.1 - 3.1 6.6 5.1 3.8 6.3 5.1 1.1 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) RR_TM4-6 PF06459.12 KFX96189.1 - 5.6 6.7 13.4 7.6 6.3 13.4 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Pet100 PF09803.9 KFX96189.1 - 8.7 7.0 6.6 19 5.9 6.6 1.7 1 1 0 1 1 1 0 Pet100 Arginosuc_synth PF00764.19 KFX96195.1 - 7e-84 282.3 0.0 7.8e-84 282.2 0.0 1.0 1 0 0 1 1 1 1 Arginosuccinate synthase Arginosuc_synth PF00764.19 KFX96196.1 - 7.3e-59 200.0 0.0 8.7e-59 199.7 0.0 1.0 1 0 0 1 1 1 1 Arginosuccinate synthase QueC PF06508.13 KFX96196.1 - 0.0034 16.9 0.0 0.0043 16.6 0.0 1.2 1 0 0 1 1 1 1 Queuosine biosynthesis protein QueC tRNA_Me_trans PF03054.16 KFX96196.1 - 0.13 11.0 0.0 0.21 10.3 0.0 1.3 1 1 0 1 1 1 0 tRNA methyl transferase Allantoicase PF03561.15 KFX96197.1 - 2.7e-91 303.0 0.0 2.5e-44 150.7 0.1 2.0 2 0 0 2 2 2 2 Allantoicase repeat F5_F8_type_C PF00754.25 KFX96197.1 - 0.03 14.4 0.1 0.12 12.5 0.0 1.9 2 0 0 2 2 2 0 F5/8 type C domain Abhydrolase_6 PF12697.7 KFX96198.1 - 8.3e-18 65.8 0.1 1.1e-17 65.4 0.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KFX96198.1 - 1.4e-09 37.5 0.0 9.3e-09 34.9 0.0 1.9 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KFX96198.1 - 9.6e-09 35.3 0.0 2.7e-07 30.5 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Apolipoprotein PF01442.18 KFX96199.1 - 0.00019 21.4 1.1 0.00019 21.4 1.1 8.0 4 2 2 7 7 7 1 Apolipoprotein A1/A4/E domain Scm3 PF10384.9 KFX96199.1 - 0.061 13.1 1.1 0.22 11.3 1.1 2.0 1 0 0 1 1 1 0 Centromere protein Scm3 Tup_N PF08581.10 KFX96199.1 - 0.28 11.5 27.0 0.66 10.3 0.1 7.3 7 0 0 7 7 7 0 Tup N-terminal Peroxin-13_N PF04088.13 KFX96199.1 - 0.49 10.7 4.4 11 6.3 0.1 3.2 2 0 0 2 2 2 0 Peroxin 13, N-terminal region DUF3289 PF11692.8 KFX96199.1 - 1 8.9 5.2 0.63 9.6 2.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3289) DUF4854 PF16146.5 KFX96199.1 - 1.4 9.2 7.7 3.2 8.1 0.1 4.8 3 1 0 3 3 3 0 Domain of unknown function (DUF4854) Gp-FAR-1 PF05823.12 KFX96199.1 - 5.2 7.4 15.2 0.52 10.7 1.0 5.3 5 2 1 6 6 6 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) HALZ PF02183.18 KFX96199.1 - 5.6 7.3 9.8 0.24 11.7 0.6 3.7 5 0 0 5 5 5 0 Homeobox associated leucine zipper Ribosomal_L27e PF01777.18 KFX96200.1 - 1.2e-37 128.2 3.4 1.5e-37 127.8 3.4 1.1 1 0 0 1 1 1 1 Ribosomal L27e protein family KOW PF00467.29 KFX96200.1 - 0.008 16.1 2.3 0.0092 15.9 0.5 2.1 2 0 0 2 2 2 1 KOW motif DUF826 PF05696.11 KFX96200.1 - 0.12 12.5 0.3 0.18 11.9 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF826) ECM11 PF15463.6 KFX96200.1 - 0.24 12.0 1.7 0.4 11.2 0.2 1.8 2 0 0 2 2 2 0 Extracellular mutant protein 11 GAF PF01590.26 KFX96201.1 - 0.0016 19.1 0.0 0.0081 16.8 0.0 2.1 2 0 0 2 2 2 1 GAF domain MGC-24 PF05283.11 KFX96201.1 - 0.39 11.2 4.3 5.4 7.5 0.0 2.7 2 0 0 2 2 2 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin ATP-synt_ab PF00006.25 KFX96202.1 - 4.8e-73 245.3 0.0 7.2e-73 244.8 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.27 KFX96202.1 - 1.5e-46 157.9 0.3 2.5e-46 157.1 0.3 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.23 KFX96202.1 - 3.7e-15 56.2 2.9 9.1e-15 54.9 2.9 1.7 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain AAA_22 PF13401.6 KFX96202.1 - 0.085 13.1 0.0 0.36 11.1 0.0 2.0 2 0 0 2 2 2 0 AAA domain Btz PF09405.10 KFX96218.1 - 9.1e-11 42.1 1.0 2e-10 41.0 0.1 2.0 2 0 0 2 2 2 1 CASC3/Barentsz eIF4AIII binding N_BRCA1_IG PF16158.5 KFX96219.1 - 4.5e-33 114.0 0.9 1.2e-32 112.6 0.0 2.3 2 0 0 2 2 2 1 Ig-like domain from next to BRCA1 gene ZZ PF00569.17 KFX96219.1 - 2.4e-20 72.0 54.4 8e-07 28.8 7.4 4.6 4 0 0 4 4 4 4 Zinc finger, ZZ type C1_2 PF03107.16 KFX96219.1 - 0.0044 17.3 38.8 0.086 13.2 5.9 4.6 4 0 0 4 4 4 3 C1 domain DEC-1_N PF04625.13 KFX96219.1 - 0.25 10.3 7.2 0.6 9.1 7.2 1.6 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region Zn_ribbon_2 PF12674.7 KFX96219.1 - 0.39 11.4 7.1 6.8 7.4 0.1 3.0 2 0 0 2 2 2 0 Putative zinc ribbon domain MBF1 PF08523.10 KFX96220.1 - 2.1e-26 92.2 1.5 3.5e-26 91.5 1.5 1.4 1 0 0 1 1 1 1 Multiprotein bridging factor 1 HTH_3 PF01381.22 KFX96220.1 - 2.6e-09 37.0 0.0 3.9e-09 36.4 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix MRP-L27 PF09809.9 KFX96220.1 - 0.042 13.7 0.1 0.047 13.5 0.1 1.3 1 1 0 1 1 1 0 Mitochondrial ribosomal protein L27 HTH_31 PF13560.6 KFX96220.1 - 0.084 13.2 0.0 0.15 12.5 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain RF-1 PF00472.20 KFX96222.1 - 4.2e-16 58.9 0.9 7.8e-16 58.0 0.9 1.4 1 0 0 1 1 1 1 RF-1 domain RRM_1 PF00076.22 KFX96223.1 - 1.3e-10 41.0 0.0 2.2e-10 40.2 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KFX96223.1 - 0.00036 20.1 0.0 0.00071 19.2 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) LETM1 PF07766.13 KFX96224.1 - 9.1e-15 54.7 1.6 3.6e-13 49.5 0.1 2.3 1 1 1 2 2 2 2 LETM1-like protein Amidohydro_1 PF01979.20 KFX96225.1 - 1.1e-06 28.2 0.6 1.9e-06 27.4 0.6 1.3 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_2 PF04909.14 KFX96225.1 - 7.3e-05 22.7 0.0 0.00013 21.9 0.0 1.5 1 0 0 1 1 1 1 Amidohydrolase CoA_binding_2 PF13380.6 KFX96225.1 - 0.029 14.8 0.0 0.11 13.0 0.0 2.0 2 0 0 2 2 2 0 CoA binding domain Rop PF01815.16 KFX96225.1 - 0.11 12.4 0.1 0.19 11.6 0.1 1.4 1 0 0 1 1 1 0 Rop protein Pkinase PF00069.25 KFX96227.1 - 2.7e-60 204.0 0.0 3.6e-60 203.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFX96227.1 - 2.2e-27 96.0 0.0 2.8e-27 95.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KFX96227.1 - 5.9e-08 32.4 0.0 9.3e-08 31.7 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 KFX96227.1 - 0.0006 18.7 0.0 0.0011 17.9 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KFX96227.1 - 0.0012 18.8 0.1 0.0012 18.8 0.1 1.9 3 0 0 3 3 3 1 Phosphotransferase enzyme family Kdo PF06293.14 KFX96227.1 - 0.0015 17.9 0.0 0.0025 17.2 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Podoplanin PF05808.11 KFX96229.1 - 0.01 15.9 0.8 0.021 14.9 0.8 1.5 1 0 0 1 1 1 0 Podoplanin ATG27 PF09451.10 KFX96230.1 - 1.1e-96 323.8 0.0 1.3e-96 323.6 0.0 1.0 1 0 0 1 1 1 1 Autophagy-related protein 27 CIMR PF00878.18 KFX96230.1 - 0.0002 21.5 0.0 0.034 14.2 0.0 2.8 3 0 0 3 3 3 2 Cation-independent mannose-6-phosphate receptor repeat Glutaredoxin PF00462.24 KFX96231.1 - 4.8e-12 45.9 0.0 1.4e-11 44.4 0.0 1.8 1 0 0 1 1 1 1 Glutaredoxin Med12-LCEWAV PF12145.8 KFX96231.1 - 0.076 11.8 0.2 0.099 11.5 0.2 1.1 1 0 0 1 1 1 0 Eukaryotic Mediator 12 subunit domain Mito_carr PF00153.27 KFX96266.1 - 9.2e-38 128.1 2.2 1.3e-13 50.6 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 KFX96266.1 - 0.00064 19.0 0.5 0.02 14.0 0.1 2.2 2 0 0 2 2 2 2 Gammaproteobacterial serine protease E3_UFM1_ligase PF09743.9 KFX96266.1 - 0.032 13.9 0.0 0.058 13.0 0.0 1.3 1 0 0 1 1 1 0 E3 UFM1-protein ligase 1 Ank_2 PF12796.7 KFX96267.1 - 8.1e-51 170.5 5.1 2.2e-15 57.0 0.0 4.1 2 2 2 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KFX96267.1 - 2.8e-35 120.2 0.9 2.5e-09 37.5 0.0 5.5 3 2 3 6 6 6 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFX96267.1 - 1.2e-33 111.3 2.9 0.0019 18.5 0.0 8.1 8 0 0 8 8 8 7 Ankyrin repeat Ank PF00023.30 KFX96267.1 - 4e-28 96.6 18.5 0.0013 19.1 0.1 7.8 8 0 0 8 8 8 6 Ankyrin repeat Ank_5 PF13857.6 KFX96267.1 - 2.5e-22 78.6 12.9 0.012 15.9 0.1 7.8 1 1 8 9 9 9 7 Ankyrin repeats (many copies) DUF2384 PF09722.10 KFX96267.1 - 0.0014 18.7 0.2 1.8 8.7 0.0 4.4 5 0 0 5 5 5 1 Protein of unknown function (DUF2384) FA PF08736.11 KFX96267.1 - 0.055 13.6 0.0 1.5 9.0 0.0 2.5 3 0 0 3 3 3 0 FERM adjacent (FA) polyprenyl_synt PF00348.17 KFX96268.1 - 7.4e-50 169.4 0.2 2.6e-25 88.9 0.0 2.2 1 1 1 2 2 2 2 Polyprenyl synthetase Terpene_synth_C PF03936.16 KFX96268.1 - 0.019 14.3 0.1 0.28 10.5 0.0 2.4 2 1 0 2 2 2 0 Terpene synthase family, metal binding domain Glyco_transf_28 PF03033.20 KFX96283.1 - 1.2e-17 64.2 0.0 2.8e-17 63.1 0.0 1.6 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain UDPGT PF00201.18 KFX96283.1 - 2.3e-06 26.7 0.0 3.6e-06 26.1 0.0 1.1 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.16 KFX96283.1 - 0.023 14.6 0.0 0.046 13.7 0.0 1.4 1 0 0 1 1 1 0 Glycosyltransferase family 28 C-terminal domain MARVEL PF01284.23 KFX96285.1 - 0.0086 16.1 19.1 0.1 12.6 19.1 2.0 1 1 0 1 1 1 1 Membrane-associating domain NUDE_C PF04880.13 KFX96287.1 - 1.2e-43 149.7 10.3 1.2e-43 149.7 10.3 3.9 2 1 2 4 4 2 1 NUDE protein, C-terminal conserved region Tropomyosin_1 PF12718.7 KFX96287.1 - 0.012 15.7 27.0 4.2 7.5 18.4 4.0 2 1 1 3 3 3 0 Tropomyosin like Dimer_Tnp_Tn5 PF02281.16 KFX96287.1 - 0.067 12.9 0.1 0.13 11.9 0.1 1.4 1 0 0 1 1 1 0 Transposase Tn5 dimerisation domain Fez1 PF06818.15 KFX96287.1 - 0.24 11.8 22.2 0.39 11.1 10.1 3.0 2 1 1 3 3 3 0 Fez1 ZapB PF06005.12 KFX96287.1 - 0.31 11.5 31.1 0.11 13.0 3.9 4.9 2 1 1 3 3 2 0 Cell division protein ZapB AAA_13 PF13166.6 KFX96287.1 - 0.36 9.4 15.6 0.6 8.7 15.6 1.2 1 0 0 1 1 1 0 AAA domain TPR_MLP1_2 PF07926.12 KFX96287.1 - 0.36 10.9 31.5 0.39 10.8 11.7 4.2 2 1 2 4 4 4 0 TPR/MLP1/MLP2-like protein PRKG1_interact PF15898.5 KFX96287.1 - 0.64 11.0 22.8 0.29 12.1 7.4 3.0 2 1 1 3 3 3 0 cGMP-dependent protein kinase interacting domain Filament PF00038.21 KFX96287.1 - 0.76 9.3 23.6 0.58 9.7 21.4 1.8 2 0 0 2 2 2 0 Intermediate filament protein CCDC144C PF14915.6 KFX96287.1 - 2.9 6.9 23.1 34 3.4 21.7 2.8 2 1 0 2 2 2 0 CCDC144C protein coiled-coil region DUF745 PF05335.13 KFX96287.1 - 3 7.5 15.9 0.64 9.7 12.6 1.6 2 0 0 2 2 1 0 Protein of unknown function (DUF745) Fmp27_WPPW PF10359.9 KFX96287.1 - 3 6.6 11.2 1.6 7.5 8.7 1.7 1 1 1 2 2 2 0 RNA pol II promoter Fmp27 protein domain Chibby PF14645.6 KFX96287.1 - 3.3 8.1 9.3 3.8 8.0 4.1 2.5 1 1 1 2 2 2 0 Chibby family DUF16 PF01519.16 KFX96287.1 - 4.3 7.9 16.4 0.32 11.5 5.5 2.9 2 1 1 3 3 3 0 Protein of unknown function DUF16 Prominin PF05478.11 KFX96287.1 - 6 4.7 5.5 11 3.9 5.5 1.4 1 0 0 1 1 1 0 Prominin DUF3584 PF12128.8 KFX96287.1 - 7.5 3.9 21.1 12 3.3 21.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Prefoldin_2 PF01920.20 KFX96287.1 - 8.5 6.4 22.8 0.58 10.1 5.2 4.8 2 1 1 4 4 4 0 Prefoldin subunit Cep57_MT_bd PF06657.13 KFX96287.1 - 8.7 6.9 12.7 17 5.9 0.2 3.3 2 1 1 3 3 3 0 Centrosome microtubule-binding domain of Cep57 CENP-H PF05837.12 KFX96287.1 - 9 6.8 19.8 3.5 8.1 4.5 3.2 2 1 1 3 3 3 0 Centromere protein H (CENP-H) FPP PF05911.11 KFX96287.1 - 9.8 4.2 23.0 10 4.1 15.6 2.2 1 1 1 2 2 2 0 Filament-like plant protein, long coiled-coil ATG16 PF08614.11 KFX96287.1 - 10 6.3 31.6 6.8 6.9 12.5 3.3 2 1 1 3 3 3 0 Autophagy protein 16 (ATG16) ACC_central PF08326.12 KFX96288.1 - 1.6e-286 952.4 0.0 1.9e-286 952.1 0.0 1.1 1 0 0 1 1 1 1 Acetyl-CoA carboxylase, central region Carboxyl_trans PF01039.22 KFX96288.1 - 5.5e-188 625.6 0.0 7.2e-188 625.2 0.0 1.1 1 0 0 1 1 1 1 Carboxyl transferase domain CPSase_L_D2 PF02786.17 KFX96288.1 - 6.8e-52 176.0 0.0 1.3e-51 175.1 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_N PF00289.22 KFX96288.1 - 4.3e-28 98.1 0.1 8.6e-28 97.1 0.1 1.5 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 KFX96288.1 - 1.1e-21 76.9 0.0 3.1e-19 69.1 0.0 3.7 4 0 0 4 4 4 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.22 KFX96288.1 - 4.7e-18 64.8 0.1 1.4e-17 63.2 0.1 1.9 1 0 0 1 1 1 1 Biotin-requiring enzyme GxGYxYP_N PF16216.5 KFX96288.1 - 0.0074 16.5 0.0 0.015 15.5 0.0 1.4 1 0 0 1 1 1 1 GxGYxY sequence motif in domain of unknown function N-terminal Dala_Dala_lig_C PF07478.13 KFX96288.1 - 0.0077 15.8 0.0 0.021 14.4 0.0 1.7 2 0 0 2 2 2 1 D-ala D-ala ligase C-terminus ATP-grasp_3 PF02655.14 KFX96288.1 - 0.011 15.7 0.0 0.04 14.0 0.0 2.0 1 0 0 1 1 1 0 ATP-grasp domain Beta_protein PF14350.6 KFX96288.1 - 0.046 13.1 0.0 0.082 12.3 0.0 1.3 1 0 0 1 1 1 0 Beta protein Biotin_lipoyl_2 PF13533.6 KFX96288.1 - 0.051 13.4 0.0 0.16 11.8 0.0 1.8 1 0 0 1 1 1 0 Biotin-lipoyl like ATP-grasp PF02222.22 KFX96288.1 - 0.083 12.5 0.0 0.22 11.1 0.0 1.7 1 0 0 1 1 1 0 ATP-grasp domain ATPgrasp_Ter PF15632.6 KFX96288.1 - 0.089 12.5 0.0 0.22 11.3 0.0 1.6 1 0 0 1 1 1 0 ATP-grasp in the biosynthetic pathway with Ter operon DUF3492 PF11997.8 KFX96289.1 - 0.062 13.0 0.3 0.084 12.6 0.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3492) DivIC PF04977.15 KFX96289.1 - 0.16 11.8 4.3 0.31 10.8 4.3 1.5 1 0 0 1 1 1 0 Septum formation initiator CCDC92 PF14916.6 KFX96290.1 - 0.0027 17.4 1.2 0.0072 16.1 1.2 1.7 1 0 0 1 1 1 1 Coiled-coil domain of unknown function RPOL_N PF14700.6 KFX96290.1 - 0.0082 15.6 0.4 0.0082 15.6 0.4 1.6 1 1 1 2 2 2 1 DNA-directed RNA polymerase N-terminal Vps39_2 PF10367.9 KFX96290.1 - 0.081 13.4 1.1 0.098 13.1 0.3 1.5 2 0 0 2 2 2 0 Vacuolar sorting protein 39 domain 2 DHDPS PF00701.22 KFX96290.1 - 0.085 11.6 0.0 0.099 11.3 0.0 1.1 1 0 0 1 1 1 0 Dihydrodipicolinate synthetase family F-box-like PF12937.7 KFX96292.1 - 2e-06 27.6 2.1 6.6e-06 25.9 2.1 1.9 1 1 0 1 1 1 1 F-box-like F-box PF00646.33 KFX96292.1 - 1.4 8.9 3.9 4.5 7.3 2.7 2.5 1 1 1 2 2 2 0 F-box domain Methyltransf_23 PF13489.6 KFX96293.1 - 5.1e-19 68.7 0.0 7.2e-19 68.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KFX96293.1 - 1.7e-14 54.3 0.0 3.6e-14 53.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KFX96293.1 - 9.1e-14 51.5 0.1 7.1e-06 25.9 0.0 2.2 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_11 PF08241.12 KFX96293.1 - 1.4e-13 51.3 0.0 2.7e-13 50.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KFX96293.1 - 2e-10 41.3 0.0 2.2e-09 38.0 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.17 KFX96293.1 - 0.00062 19.3 0.0 0.0013 18.3 0.0 1.5 1 0 0 1 1 1 1 Putative methyltransferase MTS PF05175.14 KFX96293.1 - 0.00071 19.2 0.0 0.0012 18.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.13 KFX96293.1 - 0.0023 17.4 0.0 0.0045 16.4 0.0 1.4 1 1 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Ubie_methyltran PF01209.18 KFX96293.1 - 0.0033 16.8 0.0 0.083 12.2 0.0 2.1 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_16 PF10294.9 KFX96293.1 - 0.0037 17.0 0.0 0.011 15.5 0.0 1.9 1 1 0 1 1 1 1 Lysine methyltransferase FtsJ PF01728.19 KFX96293.1 - 0.004 17.3 0.0 0.0064 16.6 0.0 1.2 1 0 0 1 1 1 1 FtsJ-like methyltransferase CMAS PF02353.20 KFX96293.1 - 0.0064 15.8 0.0 0.034 13.4 0.0 2.2 2 1 0 2 2 2 1 Mycolic acid cyclopropane synthetase TehB PF03848.14 KFX96293.1 - 0.02 14.3 0.0 5.5 6.4 0.0 2.1 2 0 0 2 2 2 0 Tellurite resistance protein TehB Methyltransf_2 PF00891.18 KFX96293.1 - 0.049 12.9 0.0 0.13 11.5 0.0 1.7 2 0 0 2 2 2 0 O-methyltransferase domain DUF3489 PF11994.8 KFX96293.1 - 0.082 13.0 0.1 0.15 12.1 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3489) Methyltransf_2 PF00891.18 KFX96294.1 - 3.9e-16 59.0 0.0 8.6e-16 57.9 0.0 1.6 2 0 0 2 2 2 1 O-methyltransferase domain Methyltransf_23 PF13489.6 KFX96294.1 - 0.021 14.7 0.0 0.04 13.8 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Asp PF00026.23 KFX96295.1 - 3.4e-66 223.8 3.3 4.4e-66 223.5 3.3 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KFX96295.1 - 5.1e-11 43.1 1.6 3.7e-08 33.8 1.0 2.6 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 KFX96295.1 - 4.5e-05 24.0 0.5 0.096 13.3 0.1 3.1 2 1 0 2 2 2 2 Aspartyl protease Glyoxalase PF00903.25 KFX96296.1 - 6.2e-06 26.4 0.0 9.3e-06 25.9 0.0 1.3 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily SH3_2 PF07653.17 KFX96297.1 - 3.7e-07 29.7 0.0 5.7e-07 29.1 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KFX96297.1 - 9.2e-07 28.4 0.0 2.3e-06 27.1 0.0 1.7 1 1 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KFX96297.1 - 5.3e-06 26.2 0.1 8.3e-06 25.6 0.1 1.3 1 0 0 1 1 1 1 Variant SH3 domain Peroxin-13_N PF04088.13 KFX96297.1 - 1.8e-05 25.0 0.0 2.5e-05 24.6 0.0 1.2 1 0 0 1 1 1 1 Peroxin 13, N-terminal region Ferric_reduct PF01794.19 KFX96299.1 - 6.4e-13 48.9 4.6 6.4e-13 48.9 4.6 2.2 1 1 1 2 2 2 1 Ferric reductase like transmembrane component YTH PF04146.15 KFX96302.1 - 2.4e-57 193.5 0.0 2.9e-57 193.2 0.0 1.1 1 0 0 1 1 1 1 YT521-B-like domain Drf_GBD PF06371.13 KFX96307.1 - 7.5e-66 221.3 0.8 1.9e-65 220.0 0.0 1.9 2 0 0 2 2 2 1 Diaphanous GTPase-binding Domain Drf_FH3 PF06367.16 KFX96307.1 - 1.4e-52 178.1 1.7 1e-51 175.3 0.7 2.4 1 1 1 2 2 2 1 Diaphanous FH3 Domain GTA_holin_3TM PF11351.8 KFX96307.1 - 0.39 11.3 4.1 1 9.9 4.1 1.8 1 0 0 1 1 1 0 Holin of 3TMs, for gene-transfer release Helicase_PWI PF18149.1 KFX96333.1 - 9.1e-35 119.2 2.4 9.1e-35 119.2 2.4 2.1 2 0 0 2 2 2 1 N-terminal helicase PWI domain DEAD PF00270.29 KFX96333.1 - 1.8e-28 99.5 0.0 1.2e-27 96.8 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase ResIII PF04851.15 KFX96333.1 - 7.4e-14 52.1 0.0 1.8e-13 50.8 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 KFX96333.1 - 1.3e-06 28.7 0.0 1.7e-05 25.1 0.0 2.4 1 1 0 1 1 1 1 Helicase conserved C-terminal domain AAA_22 PF13401.6 KFX96333.1 - 0.0016 18.8 0.2 0.0086 16.4 0.2 2.2 1 1 0 1 1 1 1 AAA domain DUF4315 PF14193.6 KFX96334.1 - 1.6 8.8 10.9 0.26 11.3 1.0 3.1 2 1 0 2 2 2 0 Domain of unknown function (DUF4315) CPSase_L_D2 PF02786.17 KFX96335.1 - 7.4e-110 365.4 0.2 1.9e-83 279.2 0.0 2.3 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_D3 PF02787.19 KFX96335.1 - 3.4e-41 140.4 0.0 1.1e-40 138.8 0.0 2.0 1 0 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain ATP-grasp PF02222.22 KFX96335.1 - 4.5e-19 68.7 0.1 6.4e-09 35.6 0.0 2.6 2 0 0 2 2 2 2 ATP-grasp domain Dala_Dala_lig_C PF07478.13 KFX96335.1 - 1.2e-18 67.4 1.0 8.6e-09 35.2 0.2 2.5 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus ATPgrasp_Ter PF15632.6 KFX96335.1 - 4.2e-12 46.0 0.0 2.7e-05 23.9 0.0 2.9 2 0 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon RimK PF08443.11 KFX96335.1 - 4.7e-06 26.3 0.1 0.0012 18.5 0.0 2.5 2 0 0 2 2 2 2 RimK-like ATP-grasp domain GARS_A PF01071.19 KFX96335.1 - 4.6e-05 23.3 0.3 0.016 15.0 0.1 2.7 2 0 0 2 2 2 2 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain ATP-grasp_3 PF02655.14 KFX96335.1 - 8.3e-05 22.7 0.2 0.29 11.2 0.0 2.7 3 0 0 3 3 2 2 ATP-grasp domain ATP-grasp_5 PF13549.6 KFX96335.1 - 0.00056 19.4 0.1 0.16 11.4 0.0 2.8 2 0 0 2 2 2 1 ATP-grasp domain ATP-grasp_4 PF13535.6 KFX96335.1 - 0.0096 15.5 0.2 0.053 13.1 0.1 2.3 2 0 0 2 2 2 1 ATP-grasp domain KR PF08659.10 KFX96335.1 - 0.073 13.0 0.0 1.1 9.1 0.0 2.5 2 0 0 2 2 2 0 KR domain MGS PF02142.22 KFX96335.1 - 0.11 12.7 0.0 0.38 11.0 0.0 2.0 2 0 0 2 2 2 0 MGS-like domain tRNA-synt_2d PF01409.20 KFX96336.1 - 3.5e-80 269.0 0.0 5e-80 268.5 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II core domain (F) PheRS_DBD3 PF18553.1 KFX96336.1 - 6.9e-17 61.5 0.6 1.6e-16 60.3 0.6 1.7 1 0 0 1 1 1 1 PheRS DNA binding domain 3 tRNA_synthFbeta PF17759.1 KFX96336.1 - 1e-05 25.1 0.0 0.011 15.2 0.0 2.6 2 0 0 2 2 2 2 Phenylalanyl tRNA synthetase beta chain CLM domain tRNA-synt_2 PF00152.20 KFX96336.1 - 0.00039 19.6 0.0 0.0027 16.8 0.0 2.2 3 0 0 3 3 3 1 tRNA synthetases class II (D, K and N) PheRS_DBD2 PF18554.1 KFX96336.1 - 0.035 14.1 0.5 0.035 14.1 0.5 3.0 3 0 0 3 3 3 0 PheRS DNA binding domain 2 Tox-REase-5 PF15648.6 KFX96337.1 - 0.0061 17.0 0.6 0.0081 16.6 0.6 1.2 1 0 0 1 1 1 1 Restriction endonuclease fold toxin 5 Sec66 PF09802.9 KFX96338.1 - 2.1e-80 268.6 0.1 2.5e-80 268.3 0.1 1.1 1 0 0 1 1 1 1 Preprotein translocase subunit Sec66 DUF3848 PF12959.7 KFX96338.1 - 0.029 14.4 0.0 0.062 13.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3848) NPL4 PF05021.15 KFX96339.1 - 4.1e-138 459.9 0.0 5.7e-138 459.4 0.0 1.2 1 0 0 1 1 1 1 NPL4 family zf-NPL4 PF05020.15 KFX96339.1 - 9.9e-68 226.8 0.0 1.5e-67 226.2 0.0 1.3 1 0 0 1 1 1 1 NPL4 family, putative zinc binding region UN_NPL4 PF11543.8 KFX96339.1 - 0.00014 22.2 0.0 0.00044 20.7 0.0 1.8 1 1 0 1 1 1 1 Nuclear pore localisation protein NPL4 SLAC1 PF03595.17 KFX96340.1 - 5e-59 200.2 43.3 5.7e-59 200.0 43.3 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel ORC3_N PF07034.11 KFX96341.1 - 1.1e-46 159.5 4.4 5.1e-45 154.0 4.4 2.2 1 1 0 1 1 1 1 Origin recognition complex (ORC) subunit 3 N-terminus ORC_WH_C PF18137.1 KFX96341.1 - 1.3e-28 99.8 0.1 2.4e-16 60.1 0.0 2.6 1 1 1 2 2 2 2 Origin recognition complex winged helix C-terminal PPR_3 PF13812.6 KFX96342.1 - 2.6e-05 24.2 0.0 0.2 11.8 0.0 3.1 3 0 0 3 3 3 2 Pentatricopeptide repeat domain DUF4187 PF13821.6 KFX96343.1 - 4.7e-24 83.9 2.5 1.2e-23 82.6 2.5 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4187) G-patch PF01585.23 KFX96343.1 - 4.7e-10 39.2 1.4 9.1e-10 38.3 1.4 1.5 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.7 KFX96343.1 - 0.00029 20.9 0.9 0.0011 19.0 0.9 2.1 1 0 0 1 1 1 1 G-patch domain Nop14 PF04147.12 KFX96344.1 - 2.7e-293 975.5 17.1 3.3e-293 975.2 17.1 1.1 1 0 0 1 1 1 1 Nop14-like family Cylicin_N PF15241.6 KFX96344.1 - 2.6 8.2 6.4 0.25 11.5 1.0 2.1 2 0 0 2 2 2 0 Cylicin N-terminus BTB PF00651.31 KFX96345.1 - 0.041 14.1 0.0 0.23 11.7 0.0 2.0 2 0 0 2 2 2 0 BTB/POZ domain Pkinase PF00069.25 KFX96346.1 - 6.3e-67 225.7 0.0 8.2e-67 225.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFX96346.1 - 3.4e-33 115.0 0.0 1.3e-32 113.1 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KFX96346.1 - 0.00027 20.4 0.1 0.0079 15.5 0.0 2.5 2 1 0 2 2 2 1 Kinase-like Kdo PF06293.14 KFX96346.1 - 0.0018 17.6 0.0 0.003 16.9 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KFX96346.1 - 0.0082 16.1 0.1 0.017 15.1 0.1 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family BES1_N PF05687.13 KFX96346.1 - 0.0097 16.3 1.6 0.0097 16.3 1.6 2.3 3 0 0 3 3 3 1 BES1/BZR1 plant transcription factor, N-terminal Haspin_kinase PF12330.8 KFX96346.1 - 0.022 13.7 0.1 0.036 13.0 0.1 1.2 1 0 0 1 1 1 0 Haspin like kinase domain FTA2 PF13095.6 KFX96346.1 - 0.041 13.5 0.2 2.1 7.9 0.0 2.2 1 1 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 ANAPC_CDC26 PF10471.9 KFX96347.1 - 0.086 13.7 0.3 0.36 11.7 0.0 2.2 2 0 0 2 2 2 0 Anaphase-promoting complex APC subunit CDC26 Mo25 PF08569.11 KFX96349.1 - 4e-129 430.7 0.0 5.8e-129 430.2 0.0 1.2 1 0 0 1 1 1 1 Mo25-like SWIB PF02201.18 KFX96349.1 - 1.3e-20 73.0 0.0 3.2e-20 71.8 0.0 1.7 1 0 0 1 1 1 1 SWIB/MDM2 domain PBP1_TM PF14812.6 KFX96349.1 - 0.074 13.4 4.5 0.25 11.8 4.5 1.9 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal CENP-B_dimeris PF09026.10 KFX96349.1 - 0.11 12.9 6.3 0.25 11.8 6.3 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain NOA36 PF06524.12 KFX96349.1 - 0.39 10.0 8.1 0.62 9.3 8.1 1.2 1 0 0 1 1 1 0 NOA36 protein FAM176 PF14851.6 KFX96349.1 - 0.69 9.6 3.4 1.7 8.3 3.4 1.6 1 0 0 1 1 1 0 FAM176 family Methyltransf_25 PF13649.6 KFX96350.1 - 3.2e-13 50.2 0.1 1.8e-12 47.8 0.0 2.3 3 0 0 3 3 2 1 Methyltransferase domain PrmA PF06325.13 KFX96350.1 - 1.4e-11 44.3 0.0 2.9e-11 43.3 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_11 PF08241.12 KFX96350.1 - 1.5e-11 44.8 0.0 8.8e-11 42.3 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 KFX96350.1 - 1.5e-10 41.0 0.0 3e-10 40.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KFX96350.1 - 8.4e-07 29.0 0.0 3.9e-06 26.8 0.0 2.0 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.7 KFX96350.1 - 1e-06 28.7 0.0 1.9e-06 27.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KFX96350.1 - 8.3e-06 25.4 0.1 1.5e-05 24.7 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase small domain CMAS PF02353.20 KFX96350.1 - 3.5e-05 23.3 0.1 0.00037 19.9 0.0 2.2 2 0 0 2 2 2 1 Mycolic acid cyclopropane synthetase Methyltransf_9 PF08003.11 KFX96350.1 - 0.00084 18.4 0.0 0.0013 17.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Met_10 PF02475.16 KFX96350.1 - 0.00092 19.0 0.0 0.0018 18.0 0.0 1.4 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_16 PF10294.9 KFX96350.1 - 0.0012 18.6 0.0 0.002 17.9 0.0 1.4 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_12 PF08242.12 KFX96350.1 - 0.0017 19.1 0.0 0.0045 17.7 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 KFX96350.1 - 0.0027 17.5 0.0 0.0044 16.8 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) TehB PF03848.14 KFX96350.1 - 0.0038 16.7 0.0 0.0063 15.9 0.0 1.3 1 0 0 1 1 1 1 Tellurite resistance protein TehB Ubie_methyltran PF01209.18 KFX96350.1 - 0.0049 16.2 0.0 0.0083 15.5 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family FtsJ PF01728.19 KFX96350.1 - 0.018 15.1 0.0 0.041 14.0 0.0 1.5 1 0 0 1 1 1 0 FtsJ-like methyltransferase Cons_hypoth95 PF03602.15 KFX96350.1 - 0.055 13.1 0.0 0.096 12.3 0.0 1.4 1 0 0 1 1 1 0 Conserved hypothetical protein 95 UPF0020 PF01170.18 KFX96350.1 - 0.059 13.0 0.0 0.11 12.2 0.0 1.4 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 Methyltransf_24 PF13578.6 KFX96350.1 - 0.066 14.2 0.0 0.47 11.5 0.0 2.4 2 0 0 2 2 2 0 Methyltransferase domain WD40_alt PF14077.6 KFX96350.1 - 0.13 12.2 0.3 0.26 11.2 0.3 1.4 1 0 0 1 1 1 0 Alternative WD40 repeat motif OPT PF03169.15 KFX96351.1 - 2.4e-148 495.5 27.2 2.8e-148 495.3 27.2 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein Phage_holin_2_1 PF04971.12 KFX96351.1 - 0.35 10.9 2.3 0.7 9.9 0.1 2.6 2 0 0 2 2 2 0 Bacteriophage P21 holin S Rav1p_C PF12234.8 KFX96352.1 - 1.7e-281 935.3 0.4 2.3e-281 934.8 0.4 1.2 1 0 0 1 1 1 1 RAVE protein 1 C terminal Sfi1 PF08457.10 KFX96352.1 - 2.4e-122 409.4 70.7 2.4e-122 409.4 70.7 2.2 1 1 1 2 2 2 2 Sfi1 spindle body protein WD40 PF00400.32 KFX96352.1 - 0.049 14.5 2.6 42 5.2 0.0 5.1 5 0 0 5 5 5 0 WD domain, G-beta repeat tRNA-synt_1 PF00133.22 KFX96353.1 - 1.9e-222 739.8 0.0 2.6e-222 739.4 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 KFX96353.1 - 1.5e-22 80.2 0.0 5.6e-22 78.3 0.0 2.0 2 0 0 2 2 2 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 KFX96353.1 - 3.1e-15 55.8 0.1 5e-06 25.5 0.0 4.0 3 1 0 3 3 3 3 tRNA synthetases class I (M) tRNA-synt_1e PF01406.19 KFX96353.1 - 0.0086 15.5 0.0 0.075 12.4 0.0 2.2 2 0 0 2 2 2 1 tRNA synthetases class I (C) catalytic domain Uso1_p115_head PF04869.14 KFX96354.1 - 6.7e-117 390.1 0.0 1.3e-116 389.1 0.0 1.5 1 0 0 1 1 1 1 Uso1 / p115 like vesicle tethering protein, head region Uso1_p115_C PF04871.13 KFX96354.1 - 4.5e-15 56.1 26.4 4.5e-15 56.1 26.4 2.9 1 1 1 2 2 2 1 Uso1 / p115 like vesicle tethering protein, C terminal region Atx10homo_assoc PF09759.9 KFX96354.1 - 0.0044 17.0 0.9 9.8 6.3 0.1 4.1 4 0 0 4 4 4 2 Spinocerebellar ataxia type 10 protein domain Prominin PF05478.11 KFX96354.1 - 9.7 4.0 18.1 15 3.4 18.1 1.2 1 0 0 1 1 1 0 Prominin XRN_M PF17846.1 KFX96355.1 - 1.1e-142 476.1 0.0 3.9e-142 474.3 0.0 1.9 1 1 0 1 1 1 1 Xrn1 helical domain XRN_N PF03159.18 KFX96355.1 - 3.2e-98 328.0 0.0 6.3e-98 327.0 0.0 1.5 1 0 0 1 1 1 1 XRN 5'-3' exonuclease N-terminus RasGAP PF00616.19 KFX96355.1 - 1.6e-34 119.5 0.8 3.8e-22 79.0 0.1 2.5 1 1 1 2 2 2 2 GTPase-activator protein for Ras-like GTPase CRAL_TRIO_2 PF13716.6 KFX96355.1 - 1.7e-08 34.7 0.1 4.6e-08 33.3 0.1 1.8 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain Porphobil_deam PF01379.20 KFX96355.1 - 0.13 11.7 0.1 0.32 10.5 0.1 1.5 1 0 0 1 1 1 0 Porphobilinogen deaminase, dipyromethane cofactor binding domain MOR2-PAG1_C PF14225.6 KFX96355.1 - 0.27 11.1 2.5 0.36 10.7 0.5 2.4 3 0 0 3 3 3 0 Cell morphogenesis C-terminal zf-CCHC PF00098.23 KFX96355.1 - 0.27 11.4 2.0 0.66 10.2 2.0 1.7 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_2 PF13696.6 KFX96355.1 - 0.31 10.9 1.4 0.68 9.8 1.4 1.6 1 0 0 1 1 1 0 Zinc knuckle HEAT PF02985.22 KFX96355.1 - 0.78 10.2 3.3 22 5.6 0.0 4.8 4 0 0 4 4 4 0 HEAT repeat FAD_binding_3 PF01494.19 KFX96356.1 - 6.9e-09 35.4 6.3 5.3e-07 29.2 1.9 3.0 2 1 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 KFX96356.1 - 0.001 19.3 1.1 0.0022 18.2 1.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KFX96356.1 - 0.0045 16.3 1.3 0.014 14.7 0.7 1.9 1 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KFX96356.1 - 0.016 15.2 0.0 0.029 14.3 0.0 1.4 1 1 0 1 1 1 0 FAD-NAD(P)-binding DAO PF01266.24 KFX96356.1 - 0.027 14.0 5.2 0.13 11.8 2.9 2.3 1 1 0 2 2 2 0 FAD dependent oxidoreductase Thi4 PF01946.17 KFX96356.1 - 0.064 12.5 0.6 0.11 11.8 0.6 1.3 1 0 0 1 1 1 0 Thi4 family FAD_binding_2 PF00890.24 KFX96356.1 - 0.2 10.7 1.0 0.88 8.6 0.9 1.9 2 0 0 2 2 2 0 FAD binding domain MFS_1 PF07690.16 KFX96357.1 - 4.9e-11 42.1 20.3 3.8e-09 35.9 19.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2530 PF10745.9 KFX96357.1 - 0.068 13.4 3.6 0.13 12.6 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF2530) DUF2070 PF09843.9 KFX96357.1 - 0.34 9.1 6.7 0.41 8.9 6.7 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) SecD_SecF PF02355.16 KFX96357.1 - 0.38 10.1 5.9 5 6.5 0.1 2.8 3 0 0 3 3 3 0 Protein export membrane protein Acyl_transf_3 PF01757.22 KFX96357.1 - 0.82 8.7 17.7 0.029 13.5 9.3 2.2 2 1 0 2 2 2 0 Acyltransferase family Sec7 PF01369.20 KFX96359.1 - 1.7e-28 99.6 0.0 3.7e-28 98.4 0.0 1.5 1 0 0 1 1 1 1 Sec7 domain PH_9 PF15410.6 KFX96359.1 - 2.5e-20 73.0 0.0 5.1e-20 72.0 0.0 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain FAD_binding_8 PF08022.12 KFX96375.1 - 4e-10 39.7 0.2 8.5e-10 38.7 0.2 1.4 1 0 0 1 1 1 1 FAD-binding domain Pkinase PF00069.25 KFX96375.1 - 1.6e-09 37.6 0.0 4.7e-09 36.0 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Ferric_reduct PF01794.19 KFX96375.1 - 1.2e-08 35.1 8.8 1.2e-08 35.1 8.8 2.9 2 1 1 3 3 3 1 Ferric reductase like transmembrane component Pkinase_Tyr PF07714.17 KFX96375.1 - 7.7e-07 28.7 0.0 1.3e-06 27.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase NAD_binding_6 PF08030.12 KFX96375.1 - 8.1e-07 29.3 0.0 2.3e-06 27.8 0.0 1.9 1 1 0 1 1 1 1 Ferric reductase NAD binding domain CPBP PF02517.16 KFX96379.1 - 1e-12 48.3 14.4 1e-12 48.3 14.4 2.8 2 1 0 2 2 2 1 CPBP intramembrane metalloprotease MBOAT PF03062.19 KFX96380.1 - 9.3e-48 163.3 6.8 9.3e-48 163.3 6.8 1.7 1 1 0 2 2 2 1 MBOAT, membrane-bound O-acyltransferase family Sec1 PF00995.23 KFX96381.1 - 1.7e-133 446.9 0.9 1.9e-133 446.7 0.9 1.0 1 0 0 1 1 1 1 Sec1 family HEAT_2 PF13646.6 KFX96381.1 - 0.056 13.8 0.2 1.7 9.1 0.1 2.9 3 0 0 3 3 3 0 HEAT repeats Glyco_hydro_7 PF00840.20 KFX96390.1 - 6.9e-208 690.7 19.2 8.2e-208 690.4 19.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 7 CBM_1 PF00734.18 KFX96390.1 - 5.1e-13 48.7 14.4 5.1e-13 48.7 14.4 4.7 4 1 0 4 4 4 1 Fungal cellulose binding domain BetaGal_dom4_5 PF13364.6 KFX96393.1 - 2.9e-27 95.5 0.0 4.3e-27 94.9 0.0 1.2 1 0 0 1 1 1 1 Beta-galactosidase jelly roll domain Glyco_hydro_31 PF01055.26 KFX96394.1 - 4.3e-157 523.8 0.3 5.5e-157 523.5 0.3 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 NtCtMGAM_N PF16863.5 KFX96394.1 - 3.3e-40 136.9 0.1 5.9e-40 136.1 0.1 1.4 1 0 0 1 1 1 1 N-terminal barrel of NtMGAM and CtMGAM, maltase-glucoamylase Gal_mutarotas_2 PF13802.6 KFX96394.1 - 5.2e-14 52.3 5.1 9.7e-14 51.4 0.8 3.1 3 0 0 3 3 3 1 Galactose mutarotase-like DUF5110 PF17137.4 KFX96394.1 - 0.036 14.3 0.1 0.14 12.5 0.1 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF5110) TIG PF01833.24 KFX96394.1 - 0.11 12.6 2.4 7.5 6.7 0.1 3.6 3 1 1 4 4 4 0 IPT/TIG domain BRCT_2 PF16589.5 KFX96395.1 - 5.5e-06 26.7 0.0 7e-05 23.2 0.0 2.9 2 1 0 2 2 2 1 BRCT domain, a BRCA1 C-terminus domain BRCT PF00533.26 KFX96395.1 - 0.00025 21.4 0.0 0.0018 18.6 0.0 2.5 2 1 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain BRCT_3 PF18428.1 KFX96395.1 - 0.0094 16.0 0.0 6.7 6.9 0.0 2.8 2 0 0 2 2 2 2 BRCA1 C Terminus (BRCT) domain Sugar_tr PF00083.24 KFX96399.1 - 5.9e-75 252.8 16.7 6e-74 249.5 16.7 1.9 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KFX96399.1 - 7.2e-17 61.3 26.2 4.4e-15 55.5 22.4 2.2 2 0 0 2 2 2 2 Major Facilitator Superfamily Dioxygenase_C PF00775.21 KFX96400.1 - 4e-10 39.4 0.2 8.6e-10 38.3 0.2 1.5 1 0 0 1 1 1 1 Dioxygenase DUF4198 PF10670.9 KFX96400.1 - 0.022 15.1 0.1 0.051 13.9 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4198) Aldo_ket_red PF00248.21 KFX96401.1 - 1.3e-42 146.0 0.0 2.2e-40 138.7 0.0 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family Slx4 PF09494.10 KFX96402.1 - 3.7e-24 84.4 0.0 8.1e-24 83.3 0.0 1.6 1 0 0 1 1 1 1 Slx4 endonuclease Ish1 PF10281.9 KFX96402.1 - 0.035 14.4 0.1 0.39 11.1 0.0 2.6 2 0 0 2 2 2 0 Putative stress-responsive nuclear envelope protein NDT80_PhoG PF05224.12 KFX96402.1 - 3.4 7.9 5.1 0.46 10.7 0.6 1.8 2 0 0 2 2 2 0 NDT80 / PhoG like DNA-binding family FXR_C1 PF16096.5 KFX96403.1 - 0.081 13.1 0.1 0.22 11.8 0.0 1.8 1 1 0 1 1 1 0 Fragile X-related 1 protein C-terminal region 2 Ribosomal_S21e PF01249.18 KFX96404.1 - 3e-37 126.6 0.1 3.5e-37 126.4 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein S21e ApbA_C PF08546.11 KFX96405.1 - 2.4e-24 85.9 0.0 4.9e-24 84.9 0.0 1.5 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.16 KFX96405.1 - 6.2e-24 84.4 0.0 1.2e-23 83.4 0.0 1.5 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Zn_clus PF00172.18 KFX96405.1 - 0.0032 17.6 12.1 0.0051 16.9 12.1 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Peptidase_A4 PF01828.17 KFX96406.1 - 5.1e-74 248.2 19.4 6.3e-74 248.0 19.4 1.1 1 0 0 1 1 1 1 Peptidase A4 family Glyco_hydro_7 PF00840.20 KFX96407.1 - 4.8e-84 282.6 25.2 2.8e-28 98.9 6.3 5.0 1 1 3 4 4 4 4 Glycosyl hydrolase family 7 BNR_2 PF13088.6 KFX96408.1 - 0.037 13.3 0.1 0.22 10.8 0.1 2.0 1 1 0 2 2 2 0 BNR repeat-like domain LIP PF03583.14 KFX96409.1 - 2.6e-61 207.5 0.7 3.4e-61 207.1 0.7 1.1 1 0 0 1 1 1 1 Secretory lipase Peptidase_S9 PF00326.21 KFX96409.1 - 1.3e-06 28.1 0.1 0.00019 21.0 0.0 2.7 2 1 1 3 3 3 1 Prolyl oligopeptidase family DLH PF01738.18 KFX96409.1 - 0.0031 17.1 0.0 0.0063 16.1 0.0 1.5 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_2 PF02230.16 KFX96409.1 - 0.0038 17.0 0.0 0.0068 16.2 0.0 1.4 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Hydrolase_4 PF12146.8 KFX96409.1 - 0.093 12.0 0.0 0.36 10.1 0.0 1.8 2 0 0 2 2 2 0 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KFX96409.1 - 0.11 12.1 0.2 0.2 11.2 0.0 1.5 2 0 0 2 2 2 0 alpha/beta hydrolase fold Amidase PF01425.21 KFX96410.1 - 2.3e-76 257.6 0.2 1.9e-75 254.6 0.2 1.9 1 1 0 1 1 1 1 Amidase p450 PF00067.22 KFX96411.1 - 1.9e-66 224.7 0.0 3e-66 224.1 0.0 1.3 1 0 0 1 1 1 1 Cytochrome P450 MFS_1 PF07690.16 KFX96411.1 - 5.4e-39 134.1 23.5 5.4e-39 134.1 23.5 5.5 2 2 3 5 5 5 2 Major Facilitator Superfamily Transp_cyt_pur PF02133.15 KFX96411.1 - 5.3e-33 114.5 38.4 5.3e-33 114.5 38.4 2.6 2 0 0 2 2 2 1 Permease for cytosine/purines, uracil, thiamine, allantoin Fungal_trans PF04082.18 KFX96411.1 - 2.7e-17 62.7 0.0 5e-17 61.8 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KFX96411.1 - 2.3e-05 24.4 11.6 4.1e-05 23.6 11.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MWFE PF15879.5 KFX96411.1 - 0.14 12.4 0.0 0.85 9.8 0.0 2.5 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase MWFE subunit Aldo_ket_red PF00248.21 KFX96412.1 - 6.9e-72 242.1 0.1 1.4e-71 241.1 0.1 1.5 2 0 0 2 2 2 1 Aldo/keto reductase family HET PF06985.11 KFX96412.1 - 6.1e-29 101.3 0.4 1.3e-28 100.2 0.0 1.7 2 0 0 2 2 2 1 Heterokaryon incompatibility protein (HET) Condensation PF00668.20 KFX96412.1 - 0.0075 15.0 0.1 0.012 14.3 0.1 1.2 1 0 0 1 1 1 1 Condensation domain Zip PF02535.22 KFX96416.1 - 5.3e-30 104.8 2.0 5.7e-30 104.7 2.0 1.1 1 0 0 1 1 1 1 ZIP Zinc transporter E1_dh PF00676.20 KFX96417.1 - 2.2e-115 384.7 0.7 2.7e-115 384.4 0.7 1.1 1 0 0 1 1 1 1 Dehydrogenase E1 component DXP_synthase_N PF13292.6 KFX96417.1 - 5.2e-05 22.6 0.1 0.0001 21.6 0.1 1.5 1 0 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase WD40 PF00400.32 KFX96418.1 - 9.3e-39 130.7 24.3 5.7e-07 30.1 0.1 7.7 8 0 0 8 8 8 6 WD domain, G-beta repeat F-box-like PF12937.7 KFX96418.1 - 3.2e-11 42.9 0.3 6.9e-11 41.9 0.3 1.6 1 0 0 1 1 1 1 F-box-like ANAPC4_WD40 PF12894.7 KFX96418.1 - 5.1e-11 42.7 1.0 0.028 14.7 0.0 6.4 2 1 6 8 8 8 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KFX96418.1 - 1.6e-06 27.1 4.1 0.26 9.9 0.2 5.0 1 1 5 6 6 6 3 Nucleoporin Nup120/160 F-box PF00646.33 KFX96418.1 - 1.7e-05 24.6 0.6 3.7e-05 23.5 0.6 1.6 1 0 0 1 1 1 1 F-box domain WD40_like PF17005.5 KFX96418.1 - 7.1e-05 22.3 0.0 0.0086 15.4 0.0 2.9 2 1 1 3 3 3 1 WD40-like domain BBS2_Mid PF14783.6 KFX96418.1 - 0.007 16.4 0.1 2.9 8.0 0.0 3.5 4 0 0 4 4 4 1 Ciliary BBSome complex subunit 2, middle region PQQ_2 PF13360.6 KFX96418.1 - 0.013 15.1 4.8 0.018 14.6 1.0 2.5 1 1 0 1 1 1 0 PQQ-like domain PQQ_3 PF13570.6 KFX96418.1 - 0.046 14.2 2.0 50 4.6 0.0 4.9 5 1 1 6 6 6 0 PQQ-like domain PALB2_WD40 PF16756.5 KFX96418.1 - 0.085 11.8 3.2 4.8 6.0 0.0 3.3 2 1 0 2 2 2 0 Partner and localizer of BRCA2 WD40 domain Methyltransf_23 PF13489.6 KFX96421.1 - 6.7e-20 71.6 0.0 1.2e-19 70.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KFX96421.1 - 1.8e-10 41.3 0.0 4.7e-10 40.1 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KFX96421.1 - 1.4e-07 32.1 0.0 3e-07 31.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KFX96421.1 - 7.4e-06 25.8 0.0 6.8e-05 22.7 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KFX96421.1 - 2.7e-05 24.8 0.0 0.0001 23.0 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.19 KFX96421.1 - 0.0013 18.9 0.0 0.052 13.7 0.0 2.3 2 0 0 2 2 2 1 FtsJ-like methyltransferase MTS PF05175.14 KFX96421.1 - 0.032 13.8 0.0 0.078 12.5 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase small domain PrmA PF06325.13 KFX96421.1 - 0.035 13.5 0.0 0.064 12.6 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_2 PF00891.18 KFX96421.1 - 0.056 12.7 0.0 0.11 11.8 0.0 1.4 1 0 0 1 1 1 0 O-methyltransferase domain Methyltransf_4 PF02390.17 KFX96421.1 - 0.085 12.3 0.0 0.15 11.5 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase Methyltransf_2 PF00891.18 KFX96422.1 - 5e-18 65.2 0.0 7.5e-18 64.6 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase domain Dimerisation PF08100.11 KFX96422.1 - 7e-05 22.8 0.0 0.00016 21.6 0.0 1.7 1 0 0 1 1 1 1 Dimerisation domain Dimerisation2 PF16864.5 KFX96422.1 - 0.00079 19.4 0.0 0.0024 17.8 0.0 1.8 1 0 0 1 1 1 1 Dimerisation domain adh_short PF00106.25 KFX96424.1 - 2e-29 102.5 0.0 3.7e-29 101.6 0.0 1.4 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 KFX96424.1 - 5.7e-22 78.4 0.0 9.1e-22 77.8 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KFX96424.1 - 0.13 12.2 0.7 2.8 7.8 0.7 2.3 1 1 0 1 1 1 0 KR domain Eno-Rase_NADH_b PF12242.8 KFX96424.1 - 0.46 10.3 1.8 1.3 8.8 0.4 2.2 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase SKG6 PF08693.10 KFX96425.1 - 3.3e-10 39.2 0.1 5.9e-10 38.4 0.1 1.4 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Gln-synt_C PF00120.24 KFX96426.1 - 1.1e-84 284.5 0.0 1.4e-84 284.1 0.0 1.1 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain adh_short_C2 PF13561.6 KFX96427.1 - 5.4e-62 209.4 0.1 6.5e-62 209.1 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KFX96427.1 - 6.4e-42 143.2 0.0 7.9e-42 142.9 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KFX96427.1 - 2.2e-09 37.5 0.8 3.3e-09 36.9 0.8 1.2 1 0 0 1 1 1 1 KR domain 3HCDH_N PF02737.18 KFX96427.1 - 0.0002 21.3 0.1 0.00034 20.6 0.1 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Methyltransf_12 PF08242.12 KFX96427.1 - 0.00058 20.6 0.0 0.0013 19.5 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KFX96427.1 - 0.0014 19.3 0.0 0.0026 18.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Polysacc_synt_2 PF02719.15 KFX96427.1 - 0.0029 16.8 0.1 0.0042 16.3 0.1 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Methyltransf_31 PF13847.6 KFX96427.1 - 0.031 14.1 0.0 0.042 13.6 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain UDPG_MGDP_dh_N PF03721.14 KFX96427.1 - 0.055 13.0 0.0 0.093 12.3 0.0 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Methyltransf_23 PF13489.6 KFX96427.1 - 0.078 12.8 0.0 0.55 10.1 0.0 2.0 1 1 0 1 1 1 0 Methyltransferase domain MoaC PF01967.21 KFX96427.1 - 0.083 13.0 0.4 1 9.4 0.1 2.2 1 1 2 3 3 3 0 MoaC family ChuX_HutX PF06228.13 KFX96427.1 - 0.092 12.5 0.0 15 5.3 0.0 2.3 2 0 0 2 2 2 0 Haem utilisation ChuX/HutX TPMT PF05724.11 KFX96427.1 - 0.12 12.0 0.0 0.17 11.5 0.0 1.2 1 0 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) Methyltransf_11 PF08241.12 KFX96427.1 - 0.14 12.8 0.0 0.29 11.8 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain HET PF06985.11 KFX96428.1 - 1.8e-23 83.5 0.0 3.1e-23 82.7 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) ABC_tran PF00005.27 KFX96429.1 - 1.1e-47 162.0 0.1 2.3e-25 89.7 0.0 4.2 2 2 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 KFX96429.1 - 4.3e-14 53.0 8.3 0.0028 17.5 0.0 4.6 2 2 1 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 KFX96429.1 - 3.4e-12 46.3 0.7 0.0035 16.8 0.1 4.1 2 2 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 KFX96429.1 - 1.3e-09 38.9 0.1 0.00052 20.6 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.6 KFX96429.1 - 8.5e-08 31.8 1.1 0.0052 16.5 0.5 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 KFX96429.1 - 8.4e-07 29.1 0.0 0.045 13.8 0.0 2.9 2 0 0 2 2 2 2 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KFX96429.1 - 1.7e-06 28.0 0.2 0.012 15.6 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase Chromo PF00385.24 KFX96429.1 - 2.3e-06 27.4 0.2 4.7e-06 26.4 0.2 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain AAA_15 PF13175.6 KFX96429.1 - 1.9e-05 24.5 0.6 0.075 12.7 0.3 2.4 2 0 0 2 2 2 2 AAA ATPase domain AAA_28 PF13521.6 KFX96429.1 - 0.00026 21.3 0.0 0.04 14.2 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 KFX96429.1 - 0.0013 19.3 0.0 3.2 8.3 0.0 3.0 3 0 0 3 3 2 1 AAA domain AAA_22 PF13401.6 KFX96429.1 - 0.0015 18.8 0.4 2.3 8.5 0.1 3.3 2 1 0 2 2 2 1 AAA domain DUF87 PF01935.17 KFX96429.1 - 0.0028 17.8 0.7 0.45 10.6 0.2 2.9 2 0 0 2 2 2 1 Helicase HerA, central domain AAA_13 PF13166.6 KFX96429.1 - 0.0037 16.0 0.0 0.73 8.4 0.0 2.2 2 0 0 2 2 2 1 AAA domain SbcCD_C PF13558.6 KFX96429.1 - 0.011 15.9 0.1 4.7 7.5 0.0 3.2 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit MukB PF04310.12 KFX96429.1 - 0.018 14.8 0.2 6.2 6.5 0.1 2.5 2 0 0 2 2 2 0 MukB N-terminal AAA_27 PF13514.6 KFX96429.1 - 0.018 14.6 0.0 1.5 8.4 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 KFX96429.1 - 0.019 14.7 0.5 8.8 6.0 0.0 2.9 3 0 0 3 3 2 0 AAA domain PduV-EutP PF10662.9 KFX96429.1 - 0.021 14.6 0.1 3.6 7.3 0.0 2.6 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation MeaB PF03308.16 KFX96429.1 - 0.034 13.1 0.3 4.3 6.2 0.0 2.4 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_33 PF13671.6 KFX96429.1 - 0.046 13.9 0.0 7.4 6.7 0.0 2.7 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 KFX96429.1 - 0.046 14.1 0.0 12 6.3 0.0 3.0 3 0 0 3 3 3 0 RNA helicase DUF3584 PF12128.8 KFX96429.1 - 0.057 10.9 2.4 2.2 5.7 0.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) Dynamin_N PF00350.23 KFX96429.1 - 0.057 13.5 0.0 1.7 8.7 0.0 2.7 2 0 0 2 2 2 0 Dynamin family ALF PF03752.13 KFX96429.1 - 0.06 13.3 2.5 0.69 9.9 1.5 2.6 2 0 0 2 2 2 0 Short repeats of unknown function DUF815 PF05673.13 KFX96429.1 - 0.07 12.3 0.1 9.3 5.3 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF815) NACHT PF05729.12 KFX96429.1 - 0.09 12.7 0.4 7.7 6.4 0.0 2.6 2 0 0 2 2 2 0 NACHT domain Zeta_toxin PF06414.12 KFX96429.1 - 0.16 11.2 0.7 8 5.7 0.2 2.5 2 0 0 2 2 2 0 Zeta toxin SR-25 PF10500.9 KFX96429.1 - 0.22 11.1 2.9 0.41 10.2 2.9 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein HEAT PF02985.22 KFX96429.1 - 0.41 11.0 2.4 85 3.8 0.3 4.4 4 0 0 4 4 4 0 HEAT repeat AAA_24 PF13479.6 KFX96429.1 - 0.47 10.2 2.0 7.3 6.3 0.4 2.4 2 0 0 2 2 2 0 AAA domain DUF1275 PF06912.11 KFX96430.1 - 1.4e-48 165.4 10.0 1.8e-48 165.1 10.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1275) Bax1-I PF01027.20 KFX96430.1 - 0.9 9.3 9.8 0.92 9.3 5.1 2.2 1 1 1 2 2 2 0 Inhibitor of apoptosis-promoting Bax1 Tmemb_14 PF03647.13 KFX96430.1 - 1.5 9.6 6.0 7.5 7.4 1.5 2.7 2 1 0 2 2 2 0 Transmembrane proteins 14C DUF4131 PF13567.6 KFX96430.1 - 2.2 7.9 6.0 0.61 9.7 1.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) Mid2 PF04478.12 KFX96432.1 - 0.00019 21.3 0.3 0.00043 20.1 0.3 1.5 1 0 0 1 1 1 1 Mid2 like cell wall stress sensor SKG6 PF08693.10 KFX96432.1 - 0.0018 17.7 4.7 0.0048 16.3 4.7 1.8 1 0 0 1 1 1 1 Transmembrane alpha-helix domain NCU-G1 PF15065.6 KFX96432.1 - 0.0086 15.1 0.5 0.0086 15.1 0.5 1.7 2 0 0 2 2 2 1 Lysosomal transcription factor, NCU-G1 Hydrophobin PF01185.18 KFX96433.1 - 1.4e-05 25.6 11.6 1.4e-05 25.6 11.6 2.0 2 1 0 2 2 2 1 Fungal hydrophobin MF_alpha_N PF05436.11 KFX96433.1 - 0.029 14.3 0.0 0.045 13.7 0.0 1.3 1 0 0 1 1 1 0 Mating factor alpha precursor N-terminus Glyco_hydro_61 PF03443.14 KFX96434.1 - 1e-62 211.7 0.4 1.3e-62 211.4 0.4 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 ICL PF00463.21 KFX96435.1 - 1.3e-198 660.8 0.1 1.5e-198 660.6 0.1 1.0 1 0 0 1 1 1 1 Isocitrate lyase family PEP_mutase PF13714.6 KFX96435.1 - 4e-10 39.5 0.1 2.2e-09 37.2 0.0 2.0 2 0 0 2 2 2 1 Phosphoenolpyruvate phosphomutase DUF2458 PF10454.9 KFX96435.1 - 0.024 14.3 0.1 0.062 13.0 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2458) ubiquitin PF00240.23 KFX96439.1 - 4.6e-168 545.3 27.6 4.7e-33 112.7 0.6 5.0 5 0 0 5 5 5 5 Ubiquitin family Rad60-SLD PF11976.8 KFX96439.1 - 4.3e-79 260.4 28.3 2.9e-15 55.9 0.7 5.0 5 0 0 5 5 5 5 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 KFX96439.1 - 8.3e-28 96.7 14.8 0.00061 20.2 0.1 6.9 5 5 0 5 5 5 5 Ubiquitin-like domain TBK1_ULD PF18396.1 KFX96439.1 - 5.4e-20 71.1 5.5 0.038 13.9 0.0 5.2 5 0 0 5 5 5 5 TANK binding kinase 1 ubiquitin-like domain Ubiquitin_5 PF18037.1 KFX96439.1 - 3.3e-18 65.8 12.2 0.04 14.3 0.1 5.1 5 0 0 5 5 5 5 Ubiquitin-like domain Rad60-SLD_2 PF13881.6 KFX96439.1 - 2.2e-17 63.2 4.7 0.18 12.0 0.0 6.0 5 4 0 5 5 5 5 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 KFX96439.1 - 7e-16 58.7 2.8 0.49 11.0 0.0 5.2 1 1 3 5 5 5 5 DUF2407 ubiquitin-like domain Methyltrans_RNA PF04452.14 KFX96439.1 - 3.1e-08 33.3 1.3 2.6 7.3 0.0 4.2 4 0 0 4 4 4 4 RNA methyltransferase Ubiquitin_4 PF18036.1 KFX96439.1 - 9.8e-08 31.9 32.0 22 5.2 0.2 9.9 10 0 0 10 10 10 0 Ubiquitin-like domain DUF2870 PF11069.8 KFX96439.1 - 2.4e-07 31.0 0.0 40 4.7 0.0 5.6 5 0 0 5 5 5 0 Protein of unknown function (DUF2870) DUF3861 PF12977.7 KFX96439.1 - 5.3e-07 29.7 5.3 18 5.6 0.0 5.2 5 0 0 5 5 5 0 Domain of Unknown Function with PDB structure (DUF3861) ACT_5 PF13710.6 KFX96439.1 - 1.6e-06 27.8 7.7 13 5.7 0.0 5.3 5 0 0 5 5 5 0 ACT domain Big_7 PF17957.1 KFX96439.1 - 2.4e-06 28.2 0.6 71 4.3 0.0 5.1 5 0 0 5 5 5 0 Bacterial Ig domain UDP-g_GGTase PF06427.11 KFX96439.1 - 1.4e-05 25.2 7.4 9.9 6.3 0.0 4.9 5 0 0 5 5 5 0 UDP-glucose:Glycoprotein Glucosyltransferase DUF969 PF06149.12 KFX96439.1 - 3e-05 23.6 0.0 32 3.8 0.0 4.8 5 0 0 5 5 5 0 Protein of unknown function (DUF969) DUF493 PF04359.14 KFX96439.1 - 0.00037 21.0 0.1 1.9e+02 2.7 0.0 4.9 5 0 0 5 5 5 0 Protein of unknown function (DUF493) YcgR_2 PF12945.7 KFX96439.1 - 0.00041 20.5 9.7 38 4.5 0.1 5.2 5 0 0 5 5 5 0 Flagellar protein YcgR ORF11CD3 PF10549.9 KFX96439.1 - 0.00068 19.7 0.0 1.2e+02 2.9 0.0 5.1 5 0 0 5 5 5 0 ORF11CD3 domain ACT_4 PF13291.6 KFX96439.1 - 0.0018 18.8 2.5 1.9e+02 2.7 0.0 5.1 5 0 0 5 5 5 0 ACT domain Baculo_p48 PF04878.13 KFX96439.1 - 0.024 13.6 0.0 84 1.9 0.0 3.8 4 0 0 4 4 4 0 Baculovirus P48 protein ProRS-C_2 PF09181.10 KFX96439.1 - 0.14 12.3 9.2 1.4e+02 2.7 0.1 5.0 5 0 0 5 5 5 0 Prolyl-tRNA synthetase, C-terminal Tash_PEST PF07708.11 KFX96439.1 - 0.19 11.9 36.0 8 6.8 1.4 5.3 5 0 0 5 5 5 0 Tash protein PEST motif HAMP_N3 PF18575.1 KFX96439.1 - 0.23 11.1 3.3 2.6e+02 1.3 0.0 4.7 5 0 0 5 5 5 0 HAMP N-terminal domain 3 Myosin_N PF02736.19 KFX96439.1 - 0.28 11.0 9.4 1.4e+02 2.4 0.0 6.1 5 0 0 5 5 5 0 Myosin N-terminal SH3-like domain PI3K_p85B PF02192.16 KFX96439.1 - 5.6 6.8 13.6 1.3e+02 2.5 0.1 5.1 5 0 0 5 5 5 0 PI3-kinase family, p85-binding domain Zn_clus PF00172.18 KFX96440.1 - 0.0082 16.2 7.7 0.0082 16.2 7.7 2.0 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Prenyltrans PF00432.21 KFX96441.1 - 6.8e-25 86.5 27.2 5.9e-06 25.9 0.4 5.8 5 1 1 6 6 6 5 Prenyltransferase and squalene oxidase repeat dsrm PF00035.26 KFX96442.1 - 0.00018 22.1 0.0 0.00029 21.5 0.0 1.3 1 0 0 1 1 1 1 Double-stranded RNA binding motif DND1_DSRM PF14709.7 KFX96442.1 - 0.0027 17.9 0.0 0.004 17.4 0.0 1.4 1 1 0 1 1 1 1 double strand RNA binding domain from DEAD END PROTEIN 1 DUF2946 PF11162.8 KFX96443.1 - 0.11 13.2 2.8 0.43 11.2 2.8 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF2946) Pectate_lyase_3 PF12708.7 KFX96446.1 - 2.7e-104 347.7 11.2 4e-87 291.6 3.2 2.8 2 0 0 2 2 2 2 Pectate lyase superfamily protein WSC PF01822.19 KFX96446.1 - 1.9e-17 63.2 6.8 5.3e-17 61.8 6.8 1.8 1 0 0 1 1 1 1 WSC domain End_N_terminal PF12218.8 KFX96446.1 - 1.6e-08 34.1 2.7 0.003 17.2 0.2 2.7 2 0 0 2 2 2 2 N terminal extension of bacteriophage endosialidase Glyco_hydro_cc PF11790.8 KFX96447.1 - 2.2e-54 184.6 6.3 2.7e-54 184.3 6.3 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core WSC PF01822.19 KFX96447.1 - 5.8e-19 68.1 15.0 1.7e-18 66.6 9.5 2.6 2 0 0 2 2 2 2 WSC domain Glyco_hydro_72 PF03198.14 KFX96447.1 - 0.28 10.4 1.3 0.52 9.5 1.3 1.3 1 0 0 1 1 1 0 Glucanosyltransferase DUF1996 PF09362.10 KFX96448.1 - 2.9e-53 181.3 0.9 5e-53 180.5 0.9 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) WSC PF01822.19 KFX96448.1 - 1.9e-17 63.2 12.0 5.5e-17 61.7 12.0 1.9 1 0 0 1 1 1 1 WSC domain Glyco_hydro_cc PF11790.8 KFX96449.1 - 5.6e-59 199.6 1.5 6.6e-59 199.4 1.5 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core EOS1 PF12326.8 KFX96450.1 - 0.074 13.0 1.1 0.085 12.8 1.1 1.2 1 0 0 1 1 1 0 N-glycosylation protein Collagen_mid PF15984.5 KFX96450.1 - 0.095 12.4 3.4 0.11 12.2 3.4 1.1 1 0 0 1 1 1 0 Bacterial collagen, middle region Vma12 PF11712.8 KFX96450.1 - 0.16 12.1 5.9 0.71 9.9 5.9 1.8 1 1 0 1 1 1 0 Endoplasmic reticulum-based factor for assembly of V-ATPase Response_reg PF00072.24 KFX96452.1 - 9.5e-18 64.4 0.1 2e-17 63.3 0.1 1.6 1 0 0 1 1 1 1 Response regulator receiver domain HATPase_c PF02518.26 KFX96452.1 - 7.6e-16 58.6 0.0 1.7e-15 57.5 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 KFX96452.1 - 2.2e-13 50.0 0.1 1.6e-12 47.2 0.0 2.5 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain SesA PF17107.5 KFX96464.1 - 0.00097 19.3 0.1 0.0017 18.5 0.1 1.5 1 0 0 1 1 1 1 N-terminal domain on NACHT_NTPase and P-loop NTPases NACHT_sigma PF17106.5 KFX96464.1 - 0.0011 19.0 1.4 0.0018 18.4 1.4 1.3 1 0 0 1 1 1 1 Sigma domain on NACHT-NTPases Cyclin_N PF00134.23 KFX96475.1 - 1.5e-09 37.7 0.1 3.3e-09 36.6 0.0 1.6 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin PF08613.11 KFX96475.1 - 0.00038 20.9 0.0 0.00059 20.2 0.0 1.4 1 0 0 1 1 1 1 Cyclin PRP21_like_P PF12230.8 KFX96477.1 - 5.3e-54 183.4 15.9 1.9e-53 181.5 15.9 1.9 1 1 0 1 1 1 1 Pre-mRNA splicing factor PRP21 like protein Surp PF01805.20 KFX96477.1 - 3.7e-40 135.7 3.7 1.7e-19 69.5 0.2 2.6 2 0 0 2 2 2 2 Surp module zf_UBZ PF18439.1 KFX96477.1 - 0.0037 16.8 0.3 0.0083 15.7 0.3 1.6 1 0 0 1 1 1 1 Ubiquitin-Binding Zinc Finger Toprim_Crpt PF13342.6 KFX96477.1 - 0.078 13.0 0.2 10 6.2 0.1 2.6 2 0 0 2 2 2 0 C-terminal repeat of topoisomerase PMT PF02366.18 KFX96478.1 - 1.3e-73 247.7 7.5 2e-73 247.0 7.5 1.3 1 0 0 1 1 1 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT_4TMC PF16192.5 KFX96478.1 - 8.1e-68 227.9 11.8 8.1e-68 227.9 11.8 2.3 3 0 0 3 3 3 1 C-terminal four TMM region of protein-O-mannosyltransferase MIR PF02815.19 KFX96478.1 - 1.4e-43 148.9 0.0 2.8e-43 147.9 0.0 1.4 1 0 0 1 1 1 1 MIR domain Mito_carr PF00153.27 KFX96479.1 - 4.2e-69 228.6 1.9 1.2e-22 79.6 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 KFX96479.1 - 0.01 15.0 0.9 0.83 8.8 0.0 2.8 2 1 0 2 2 2 0 Gammaproteobacterial serine protease Sec2p PF06428.11 KFX96480.1 - 8.8e-27 92.9 19.6 8.8e-27 92.9 19.6 2.2 2 0 0 2 2 2 1 GDP/GTP exchange factor Sec2p PX PF00787.24 KFX96480.1 - 4.3e-24 84.7 0.0 9.8e-24 83.5 0.0 1.7 1 0 0 1 1 1 1 PX domain Spc7 PF08317.11 KFX96480.1 - 0.55 9.1 18.4 1.4 7.8 14.9 2.2 2 0 0 2 2 2 0 Spc7 kinetochore protein KxDL PF10241.9 KFX96480.1 - 0.57 10.5 9.2 15 5.9 0.1 2.7 2 0 0 2 2 2 0 Uncharacterized conserved protein Fib_alpha PF08702.10 KFX96480.1 - 1 9.5 8.8 1.4 9.1 5.2 2.3 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family DUF5339 PF17274.2 KFX96480.1 - 3 8.8 11.8 61 4.6 0.0 3.5 2 1 0 2 2 2 0 Family of unknown function (DUF5339) DUF4407 PF14362.6 KFX96480.1 - 4.6 6.5 16.4 14 4.9 16.4 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) MBA1 PF07961.11 KFX96481.1 - 5.2e-18 65.0 0.0 6.9e-18 64.6 0.0 1.2 1 0 0 1 1 1 1 MBA1-like protein Tim44 PF04280.15 KFX96481.1 - 2.7e-08 34.0 0.2 7.9e-08 32.5 0.1 1.7 2 0 0 2 2 2 1 Tim44-like domain Hol_Tox PF16935.5 KFX96482.1 - 7.3 6.7 7.8 1.4 9.0 0.4 3.1 2 1 0 2 2 2 0 Putative Holin-like Toxin (Hol-Tox) RRM_1 PF00076.22 KFX96483.1 - 3.4e-25 87.6 0.8 2.9e-11 43.0 0.0 3.4 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_8 PF11835.8 KFX96483.1 - 4.8e-05 23.5 0.0 0.00055 20.1 0.0 2.3 2 0 0 2 2 2 1 RRM-like domain RRM_5 PF13893.6 KFX96483.1 - 0.00037 20.1 0.0 0.037 13.6 0.0 2.4 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KFX96483.1 - 0.0021 18.1 0.1 0.53 10.4 0.0 3.2 3 0 0 3 3 3 1 RNA recognition motif RRM_Rrp7 PF17799.1 KFX96483.1 - 0.0082 16.0 0.1 0.04 13.7 0.0 2.1 2 0 0 2 2 2 1 Rrp7 RRM-like N-terminal domain Nup35_RRM_2 PF14605.6 KFX96483.1 - 0.036 14.1 0.4 8.9 6.4 0.0 3.3 3 0 0 3 3 3 0 Nup53/35/40-type RNA recognition motif PORR PF11955.8 KFX96483.1 - 0.067 12.1 0.0 0.11 11.5 0.0 1.2 1 0 0 1 1 1 0 Plant organelle RNA recognition domain RRM_3 PF08777.11 KFX96483.1 - 0.067 13.2 0.1 0.37 10.8 0.0 2.2 3 0 0 3 3 3 0 RNA binding motif E1-E2_ATPase PF00122.20 KFX96486.1 - 8.5e-40 136.2 7.3 2.1e-39 134.9 7.3 1.7 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.26 KFX96486.1 - 3.8e-27 96.0 0.0 6.3e-27 95.2 0.0 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HMA PF00403.26 KFX96486.1 - 2.2e-07 31.2 0.0 6.3e-07 29.7 0.0 1.9 1 0 0 1 1 1 1 Heavy-metal-associated domain Hydrolase_3 PF08282.12 KFX96486.1 - 0.0003 20.6 0.2 0.043 13.5 0.1 2.6 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase HAD PF12710.7 KFX96486.1 - 0.025 15.0 0.0 0.067 13.6 0.0 1.7 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 KFX96486.1 - 0.066 13.3 0.1 0.35 10.9 0.1 2.2 1 1 0 1 1 1 0 Haloacid dehalogenase-like hydrolase SNF2_N PF00176.23 KFX96487.1 - 1.1e-72 244.7 0.0 1.4e-72 244.3 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain HIRAN PF08797.11 KFX96487.1 - 1.9e-25 88.6 0.0 3.8e-25 87.6 0.0 1.6 1 0 0 1 1 1 1 HIRAN domain Helicase_C PF00271.31 KFX96487.1 - 1.3e-14 54.5 0.0 2.4e-14 53.6 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KFX96487.1 - 1.5e-06 28.4 0.0 3.6e-06 27.1 0.0 1.7 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit zf-C3HC4 PF00097.25 KFX96487.1 - 6.7e-05 22.7 8.0 0.00013 21.8 8.0 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KFX96487.1 - 0.00032 20.5 4.7 0.00065 19.5 4.7 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KFX96487.1 - 0.0011 18.8 5.7 0.0019 18.0 5.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KFX96487.1 - 0.0039 17.5 8.3 0.0094 16.3 8.3 1.7 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.6 KFX96487.1 - 0.041 13.9 7.7 0.085 12.9 7.7 1.5 1 0 0 1 1 1 0 RING-type zinc-finger UBA_4 PF14555.6 KFX96487.1 - 0.067 13.0 0.1 0.18 11.7 0.1 1.7 1 0 0 1 1 1 0 UBA-like domain zf-RING_5 PF14634.6 KFX96487.1 - 0.11 12.5 7.3 0.46 10.5 7.7 2.0 1 1 1 2 2 2 0 zinc-RING finger domain SQS_PSY PF00494.19 KFX96488.1 - 8.8e-54 182.7 0.0 1.3e-53 182.2 0.0 1.2 1 0 0 1 1 1 1 Squalene/phytoene synthase CorA PF01544.18 KFX96489.1 - 7.3e-28 97.7 11.8 3.7e-22 79.0 8.3 3.1 2 1 0 2 2 2 2 CorA-like Mg2+ transporter protein DUF503 PF04456.12 KFX96489.1 - 0.029 14.2 0.1 0.08 12.8 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF503) Yos1 PF08571.10 KFX96496.1 - 1.5e-32 111.7 0.2 1.6e-32 111.6 0.2 1.0 1 0 0 1 1 1 1 Yos1-like Fungal_trans PF04082.18 KFX96499.1 - 1.3e-20 73.6 0.0 2.1e-20 72.9 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KFX96499.1 - 7.3e-08 32.4 13.7 1.4e-07 31.5 13.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Shugoshin_N PF07558.11 KFX96499.1 - 0.0089 15.9 0.8 0.02 14.8 0.8 1.6 1 0 0 1 1 1 1 Shugoshin N-terminal coiled-coil region DUF5094 PF17015.5 KFX96499.1 - 0.32 11.1 3.9 0.49 10.5 3.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5094) Dor1 PF04124.12 KFX96505.1 - 1e-52 178.9 0.7 1.6e-41 142.1 2.5 2.1 2 0 0 2 2 2 2 Dor1-like family MS_channel PF00924.18 KFX96511.1 - 1.2e-23 83.8 2.0 2.3e-23 82.8 2.0 1.5 1 0 0 1 1 1 1 Mechanosensitive ion channel EF-hand_5 PF13202.6 KFX96511.1 - 0.00013 21.3 0.1 0.00034 20.0 0.1 1.8 1 0 0 1 1 1 1 EF hand EF-hand_1 PF00036.32 KFX96511.1 - 0.0012 18.2 0.5 0.0032 16.9 0.5 1.8 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.6 KFX96511.1 - 0.0014 18.4 0.0 0.004 17.0 0.0 1.8 1 0 0 1 1 1 1 EF-hand domain EF-hand_7 PF13499.6 KFX96511.1 - 0.0043 17.5 0.1 0.048 14.1 0.0 2.4 2 0 0 2 2 2 1 EF-hand domain pair DAO PF01266.24 KFX96512.1 - 6.6e-31 108.2 0.1 7.5e-31 108.0 0.1 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 KFX96512.1 - 0.0012 18.0 0.1 0.03 13.4 0.0 2.3 3 0 0 3 3 3 1 Lycopene cyclase protein Pyr_redox_2 PF07992.14 KFX96512.1 - 0.0032 16.8 0.1 0.023 13.9 0.1 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KFX96512.1 - 0.0074 15.6 0.0 0.98 8.6 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KFX96512.1 - 0.018 15.3 0.0 0.031 14.5 0.0 1.4 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Sacchrp_dh_NADP PF03435.18 KFX96512.1 - 0.031 14.5 0.0 0.055 13.7 0.0 1.4 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain GMC_oxred_N PF00732.19 KFX96512.1 - 0.047 13.1 0.1 0.099 12.0 0.0 1.5 2 0 0 2 2 2 0 GMC oxidoreductase NAD_binding_9 PF13454.6 KFX96512.1 - 0.055 13.5 0.1 4.9 7.1 0.0 2.2 2 0 0 2 2 2 0 FAD-NAD(P)-binding HI0933_like PF03486.14 KFX96512.1 - 0.21 10.3 0.0 0.77 8.4 0.0 1.7 2 0 0 2 2 2 0 HI0933-like protein PHM7_ext PF12621.8 KFX96514.1 - 2.6e-11 43.5 0.0 3.9e-11 43.0 0.0 1.2 1 0 0 1 1 1 1 Extracellular tail, of 10TM putative phosphate transporter HSP70 PF00012.20 KFX96515.1 - 4e-08 31.9 0.1 1.3e-05 23.6 0.1 2.3 2 1 0 2 2 2 2 Hsp70 protein Peptidase_M22 PF00814.25 KFX96515.1 - 0.091 12.4 0.0 0.17 11.6 0.0 1.4 2 0 0 2 2 2 0 Glycoprotease family BacteriocIIc_cy PF12173.8 KFX96516.1 - 0.11 12.8 0.0 0.21 11.8 0.0 1.4 1 0 0 1 1 1 0 Bacteriocin class IIc cyclic gassericin A-like Dynamin_N PF00350.23 KFX96517.1 - 9.8e-29 100.6 0.4 3.9e-28 98.6 0.0 2.1 2 0 0 2 2 2 1 Dynamin family Dynamin_M PF01031.20 KFX96517.1 - 6e-25 88.0 2.3 3.3e-24 85.6 0.6 2.6 2 1 0 2 2 2 1 Dynamin central region MMR_HSR1 PF01926.23 KFX96517.1 - 0.00013 22.1 0.0 0.00049 20.1 0.0 2.0 1 1 0 1 1 1 1 50S ribosome-binding GTPase GED PF02212.18 KFX96517.1 - 0.03 14.5 0.9 0.14 12.3 0.1 2.6 2 1 1 3 3 3 0 Dynamin GTPase effector domain Fungal_lectin_2 PF18647.1 KFX96518.1 - 2.9e-35 120.8 0.1 4.3e-35 120.2 0.1 1.3 1 0 0 1 1 1 1 Alpha-galactosyl-binding fungal lectin AAA_13 PF13166.6 KFX96520.1 - 0.00011 21.0 5.5 0.00011 21.0 5.5 2.1 1 1 1 2 2 2 1 AAA domain IFT57 PF10498.9 KFX96520.1 - 0.00026 20.1 8.5 0.00026 20.1 8.5 1.6 1 1 1 2 2 2 1 Intra-flagellar transport protein 57 DUF3584 PF12128.8 KFX96520.1 - 0.00053 17.7 14.9 0.00084 17.0 14.9 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) Laminin_II PF06009.12 KFX96520.1 - 0.001 19.1 1.9 0.001 19.1 1.9 2.4 1 1 2 3 3 3 1 Laminin Domain II DUF1664 PF07889.12 KFX96520.1 - 0.0012 18.9 14.1 1.1 9.3 0.3 3.1 1 1 2 3 3 3 3 Protein of unknown function (DUF1664) Golgin_A5 PF09787.9 KFX96520.1 - 0.0025 17.4 17.5 0.0025 17.4 17.5 1.5 1 1 0 1 1 1 1 Golgin subfamily A member 5 Tropomyosin PF00261.20 KFX96520.1 - 0.004 16.6 8.2 0.004 16.6 8.2 2.5 1 1 2 3 3 3 1 Tropomyosin DUF5082 PF16888.5 KFX96520.1 - 0.0081 16.4 10.6 0.0081 16.4 10.6 1.7 1 1 0 1 1 1 1 Domain of unknown function (DUF5082) DUF4407 PF14362.6 KFX96520.1 - 0.0084 15.5 12.9 0.011 15.2 12.9 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4407) Rootletin PF15035.6 KFX96520.1 - 0.009 16.1 11.3 0.013 15.6 11.3 1.3 1 0 0 1 1 1 1 Ciliary rootlet component, centrosome cohesion CENP-F_leu_zip PF10473.9 KFX96520.1 - 0.014 15.5 7.8 0.014 15.5 7.8 2.5 1 1 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Occludin_ELL PF07303.13 KFX96520.1 - 0.014 16.1 7.3 0.11 13.2 3.0 2.5 1 1 2 3 3 3 0 Occludin homology domain HrpB7 PF09486.10 KFX96520.1 - 0.016 15.6 9.5 0.029 14.7 9.4 1.6 1 1 0 1 1 1 0 Bacterial type III secretion protein (HrpB7) HIP1_clath_bdg PF16515.5 KFX96520.1 - 0.032 14.9 11.4 0.032 14.9 11.4 3.0 1 1 2 3 3 3 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Myosin_tail_1 PF01576.19 KFX96520.1 - 0.057 11.2 23.9 0.23 9.2 23.9 1.6 1 1 0 1 1 1 0 Myosin tail Prp19 PF08606.11 KFX96520.1 - 0.076 13.0 2.8 2 8.4 0.2 2.5 1 1 1 2 2 2 0 Prp19/Pso4-like DUF2968 PF11180.8 KFX96520.1 - 0.079 12.6 9.1 0.071 12.7 7.6 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF2968) APG6_N PF17675.1 KFX96520.1 - 0.091 13.3 24.5 0.17 12.4 15.3 2.2 1 1 1 2 2 2 0 Apg6 coiled-coil region YabA PF06156.13 KFX96520.1 - 0.2 12.3 11.3 1.5 9.5 2.8 2.8 1 1 2 3 3 3 0 Initiation control protein YabA Filament PF00038.21 KFX96520.1 - 0.21 11.2 16.2 0.59 9.7 6.1 2.4 1 1 1 2 2 2 0 Intermediate filament protein DUF812 PF05667.11 KFX96520.1 - 0.23 10.3 16.0 0.28 10.0 16.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF812) TPR_MLP1_2 PF07926.12 KFX96520.1 - 0.25 11.4 20.9 0.56 10.3 5.5 2.6 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein Bcr-Abl_Oligo PF09036.10 KFX96520.1 - 0.3 11.1 2.6 0.6 10.1 0.1 2.6 2 1 0 2 2 2 0 Bcr-Abl oncoprotein oligomerisation domain HAUS-augmin3 PF14932.6 KFX96520.1 - 0.41 10.2 17.7 0.19 11.3 14.4 1.8 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 3 Peptidase_S46 PF10459.9 KFX96520.1 - 0.46 9.1 13.1 1.9 7.1 2.7 1.9 1 1 1 2 2 2 0 Peptidase S46 ATG16 PF08614.11 KFX96520.1 - 0.52 10.5 25.3 0.6 10.3 12.2 2.6 1 1 2 3 3 3 0 Autophagy protein 16 (ATG16) SYCE1 PF15233.6 KFX96520.1 - 0.52 10.4 19.4 1.6 8.7 9.6 3.8 1 1 3 4 4 4 0 Synaptonemal complex central element protein 1 TMF_TATA_bd PF12325.8 KFX96520.1 - 0.53 10.5 18.2 1.7 8.9 3.3 2.8 1 1 2 3 3 3 0 TATA element modulatory factor 1 TATA binding BRE1 PF08647.11 KFX96520.1 - 0.6 10.2 20.1 0.41 10.7 11.8 3.3 1 1 2 3 3 3 0 BRE1 E3 ubiquitin ligase DUF948 PF06103.11 KFX96520.1 - 0.61 10.4 3.2 1 9.6 0.5 2.5 1 1 2 3 3 3 0 Bacterial protein of unknown function (DUF948) UPF0242 PF06785.11 KFX96520.1 - 0.62 10.1 18.2 5.2 7.1 18.3 2.1 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus FUSC PF04632.12 KFX96520.1 - 0.65 8.5 2.1 0.74 8.3 2.1 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family Fez1 PF06818.15 KFX96520.1 - 0.71 10.3 19.3 5.2 7.5 17.0 2.2 1 1 1 2 2 2 0 Fez1 TolA_bind_tri PF16331.5 KFX96520.1 - 0.78 9.9 10.5 2.1 8.5 0.7 3.7 1 1 2 3 3 3 0 TolA binding protein trimerisation PKcGMP_CC PF16808.5 KFX96520.1 - 0.87 9.5 7.6 22 5.0 0.1 3.8 3 0 0 3 3 3 0 Coiled-coil N-terminus of cGMP-dependent protein kinase Atg14 PF10186.9 KFX96520.1 - 0.89 8.6 22.8 0.094 11.8 15.4 2.0 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 COG2 PF06148.11 KFX96520.1 - 1.1 9.4 14.2 0.19 11.8 1.9 3.0 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Spc7 PF08317.11 KFX96520.1 - 1.3 7.8 23.2 4.2 6.2 18.8 2.1 1 1 1 2 2 2 0 Spc7 kinetochore protein Syntaxin-6_N PF09177.11 KFX96520.1 - 1.7 9.3 14.4 0.16 12.5 2.0 3.1 1 1 2 3 3 3 0 Syntaxin 6, N-terminal Seryl_tRNA_N PF02403.22 KFX96520.1 - 1.9 8.7 19.4 1.8 8.9 2.3 2.7 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain OmpH PF03938.14 KFX96520.1 - 3.5 8.0 17.7 0.84 10.0 10.5 2.3 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) ADIP PF11559.8 KFX96520.1 - 3.5 7.7 20.3 1.2 9.2 8.8 2.4 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding NPV_P10 PF05531.12 KFX96520.1 - 4 8.0 6.6 2.2 8.8 0.4 3.0 1 1 2 3 3 3 0 Nucleopolyhedrovirus P10 protein DUF724 PF05266.14 KFX96520.1 - 4.1 7.2 18.0 0.3 10.9 8.4 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF724) Cep57_MT_bd PF06657.13 KFX96520.1 - 4.7 7.7 12.1 7.6 7.1 0.3 3.8 3 1 1 4 4 3 0 Centrosome microtubule-binding domain of Cep57 TMPIT PF07851.13 KFX96520.1 - 4.8 6.3 13.3 0.073 12.3 3.2 2.0 1 1 2 3 3 3 0 TMPIT-like protein JIP_LZII PF16471.5 KFX96520.1 - 7.2 6.9 11.5 9.3 6.5 1.3 3.3 1 1 3 4 4 3 0 JNK-interacting protein leucine zipper II KxDL PF10241.9 KFX96520.1 - 8.7 6.7 11.3 0.55 10.6 1.1 3.3 1 1 2 3 3 3 0 Uncharacterized conserved protein DUF4140 PF13600.6 KFX96520.1 - 9 6.8 14.5 71 3.9 9.2 3.5 1 1 3 4 4 4 0 N-terminal domain of unknown function (DUF4140) OTT_1508_deam PF14441.6 KFX96522.1 - 5.9e-13 48.6 0.0 1.4e-12 47.5 0.0 1.7 1 0 0 1 1 1 1 OTT_1508-like deaminase Phi29_Phage_SSB PF17427.2 KFX96522.1 - 0.42 10.8 0.0 0.42 10.8 0.0 2.4 3 0 0 3 3 3 0 Phage Single-stranded DNA-binding protein Dynamin_N PF00350.23 KFX96523.1 - 7.4e-09 35.9 0.1 2e-08 34.5 0.1 1.7 1 0 0 1 1 1 1 Dynamin family Roc PF08477.13 KFX96523.1 - 0.0052 17.0 0.2 0.23 11.7 0.0 2.6 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase AAA_28 PF13521.6 KFX96523.1 - 0.017 15.4 0.0 0.33 11.2 0.0 2.7 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.27 KFX96523.1 - 0.036 14.6 0.5 0.11 13.0 0.1 2.0 2 0 0 2 2 2 0 ABC transporter MMR_HSR1 PF01926.23 KFX96523.1 - 0.11 12.6 0.0 0.3 11.2 0.0 1.8 1 0 0 1 1 1 0 50S ribosome-binding GTPase SE PF08491.10 KFX96524.1 - 1.7e-92 309.4 0.0 3.1e-92 308.6 0.0 1.4 1 0 0 1 1 1 1 Squalene epoxidase FAD_binding_3 PF01494.19 KFX96524.1 - 4.9e-10 39.2 0.0 8.4e-10 38.4 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.7 KFX96524.1 - 1.3e-07 31.4 0.0 2.4e-07 30.5 0.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase DAO PF01266.24 KFX96524.1 - 1.4e-07 31.4 0.3 1.9e-05 24.5 0.1 3.0 3 0 0 3 3 3 1 FAD dependent oxidoreductase GIDA PF01134.22 KFX96524.1 - 5.5e-06 25.7 0.2 0.00086 18.5 0.3 2.1 2 0 0 2 2 2 2 Glucose inhibited division protein A FAD_binding_2 PF00890.24 KFX96524.1 - 1.6e-05 24.2 0.4 3.9e-05 22.9 0.4 1.7 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 KFX96524.1 - 0.00067 19.8 0.3 0.0019 18.4 0.3 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain PPR_3 PF13812.6 KFX96524.1 - 0.00084 19.4 0.0 0.043 13.9 0.0 3.0 4 0 0 4 4 3 1 Pentatricopeptide repeat domain Thi4 PF01946.17 KFX96524.1 - 0.0022 17.3 0.0 0.0068 15.7 0.0 1.8 2 0 0 2 2 2 1 Thi4 family PPR_2 PF13041.6 KFX96524.1 - 0.0043 17.2 0.0 0.024 14.8 0.0 2.3 3 0 0 3 3 2 1 PPR repeat family Pyr_redox_2 PF07992.14 KFX96524.1 - 0.007 15.6 0.0 0.012 14.8 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KFX96524.1 - 0.008 14.9 0.2 0.015 14.0 0.2 1.4 1 0 0 1 1 1 1 HI0933-like protein Trp_halogenase PF04820.14 KFX96524.1 - 0.013 14.4 0.1 1 8.1 0.3 3.0 3 0 0 3 3 3 0 Tryptophan halogenase Pyr_redox PF00070.27 KFX96524.1 - 0.015 15.9 0.4 0.08 13.5 0.2 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 KFX96524.1 - 0.018 14.4 0.1 0.034 13.5 0.1 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain 3HCDH_N PF02737.18 KFX96524.1 - 0.053 13.4 0.1 0.12 12.2 0.1 1.6 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Glycos_transf_2 PF00535.26 KFX96525.1 - 1.9e-20 73.4 0.0 2.9e-20 72.8 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 KFX96525.1 - 5.2e-09 36.3 0.1 5.9e-06 26.3 0.0 2.2 2 0 0 2 2 2 2 Glycosyltransferase like family 2 SUN PF03856.13 KFX96527.1 - 1.2e-82 277.1 10.6 1.4e-82 276.9 10.6 1.0 1 0 0 1 1 1 1 Beta-glucosidase (SUN family) LCM PF04072.14 KFX96528.1 - 2.3e-22 79.8 0.0 3.7e-22 79.2 0.0 1.3 1 0 0 1 1 1 1 Leucine carboxyl methyltransferase TFIID-18kDa PF02269.16 KFX96529.1 - 7.7e-31 106.0 1.0 3.1e-30 104.1 0.1 2.3 3 0 0 3 3 3 1 Transcription initiation factor IID, 18kD subunit TAFII28 PF04719.14 KFX96529.1 - 0.038 14.1 0.0 0.092 12.9 0.0 1.6 1 0 0 1 1 1 0 hTAFII28-like protein conserved region GFA PF04828.14 KFX96530.1 - 5.9e-08 32.9 1.4 0.00014 22.1 0.0 2.3 1 1 1 2 2 2 2 Glutathione-dependent formaldehyde-activating enzyme SET PF00856.28 KFX96531.1 - 1.3e-10 42.0 0.0 1.6e-09 38.4 0.0 2.3 1 1 0 1 1 1 1 SET domain TPR_19 PF14559.6 KFX96531.1 - 0.00061 20.3 2.6 0.01 16.3 0.1 3.0 2 1 1 3 3 3 1 Tetratricopeptide repeat ANAPC3 PF12895.7 KFX96531.1 - 0.0048 17.1 0.2 0.012 15.8 0.2 1.7 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_1 PF00515.28 KFX96531.1 - 0.014 15.1 1.8 1.4 8.9 0.0 3.8 5 0 0 5 5 5 0 Tetratricopeptide repeat SRP_TPR_like PF17004.5 KFX96531.1 - 0.064 13.3 0.0 0.12 12.4 0.0 1.3 1 0 0 1 1 1 0 Putative TPR-like repeat TPR_8 PF13181.6 KFX96531.1 - 0.26 11.6 0.9 52 4.4 0.2 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.17 KFX96531.1 - 1 9.6 6.2 15 6.0 0.1 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_14 PF13428.6 KFX96531.1 - 3 8.9 7.9 65 4.7 0.1 4.4 3 1 1 4 4 4 0 Tetratricopeptide repeat RPT PF13446.6 KFX96565.1 - 1e-37 127.8 1.0 2.8e-13 49.6 0.2 4.6 4 0 0 4 4 4 4 A repeated domain in UCH-protein UCH PF00443.29 KFX96565.1 - 6.4e-34 117.6 4.5 4.3e-33 114.9 4.5 2.0 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KFX96565.1 - 3.4e-06 26.9 0.2 0.0007 19.3 0.0 2.4 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase VTC PF09359.10 KFX96565.1 - 0.037 13.4 0.1 0.067 12.6 0.1 1.3 1 0 0 1 1 1 0 VTC domain Tim17 PF02466.19 KFX96566.1 - 7.9e-09 35.9 7.3 1.4e-08 35.1 7.3 1.4 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family TBCC PF07986.12 KFX96567.1 - 1.8e-31 108.4 0.5 3.1e-31 107.6 0.5 1.4 1 0 0 1 1 1 1 Tubulin binding cofactor C TBCC_N PF16752.5 KFX96567.1 - 9.7e-11 42.1 0.2 2.2e-10 41.0 0.2 1.5 1 0 0 1 1 1 1 Tubulin-specific chaperone C N-terminal domain PHM7_cyt PF14703.6 KFX96567.1 - 0.032 14.5 0.6 2.3 8.4 0.0 2.4 1 1 1 2 2 2 0 Cytosolic domain of 10TM putative phosphate transporter OrsD PF12013.8 KFX96569.1 - 2.4e-15 57.0 0.0 3.9e-08 33.7 0.0 2.3 2 0 0 2 2 2 2 Orsellinic acid/F9775 biosynthesis cluster protein D DUF4826 PF16108.5 KFX96569.1 - 0.093 13.0 0.1 0.21 11.9 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4826) OrsD PF12013.8 KFX96570.1 - 2.3e-13 50.6 0.3 6.2e-13 49.2 0.3 1.8 1 0 0 1 1 1 1 Orsellinic acid/F9775 biosynthesis cluster protein D MyTH4 PF00784.17 KFX96570.1 - 0.055 14.0 0.1 6.3 7.3 0.0 2.7 2 0 0 2 2 2 0 MyTH4 domain LEA_3 PF03242.13 KFX96580.1 - 8.6 7.2 5.8 33 5.3 0.8 2.5 1 1 1 2 2 2 0 Late embryogenesis abundant protein Fungal_trans_2 PF11951.8 KFX96581.1 - 1.8e-06 27.0 0.0 2.8e-06 26.4 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain MFS_1 PF07690.16 KFX96582.1 - 4.2e-34 118.0 58.1 5.4e-33 114.4 53.2 2.8 2 1 0 2 2 2 1 Major Facilitator Superfamily MFS_2 PF13347.6 KFX96582.1 - 9.8e-05 21.1 4.0 9.8e-05 21.1 4.0 2.7 3 0 0 3 3 3 1 MFS/sugar transport protein PI3_PI4_kinase PF00454.27 KFX96586.1 - 5e-43 147.7 0.0 7.9e-40 137.2 0.0 3.4 2 1 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.20 KFX96586.1 - 1.5e-23 83.2 0.1 1.1e-22 80.3 0.0 2.2 2 0 0 2 2 2 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) Proteasome PF00227.26 KFX96587.1 - 8.6e-29 100.4 0.2 1.6e-28 99.5 0.2 1.4 1 1 0 1 1 1 1 Proteasome subunit Zn_clus PF00172.18 KFX96613.1 - 2.2e-08 34.1 15.1 3.8e-08 33.3 15.1 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 KFX96613.1 - 0.00035 19.5 0.1 0.00076 18.4 0.0 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain EF-hand_4 PF12763.7 KFX96613.1 - 0.092 12.7 0.0 0.26 11.3 0.0 1.7 2 0 0 2 2 2 0 Cytoskeletal-regulatory complex EF hand Inhibitor_I66 PF16850.5 KFX96614.1 - 1.3e-09 38.1 0.1 1.6e-09 37.8 0.1 1.1 1 0 0 1 1 1 1 Peptidase inhibitor I66 RicinB_lectin_2 PF14200.6 KFX96614.1 - 0.11 13.2 0.0 3.5 8.4 0.0 2.3 1 1 1 2 2 2 0 Ricin-type beta-trefoil lectin domain-like Phage_tail_T PF06223.12 KFX96615.1 - 0.031 14.8 7.7 6.1 7.4 0.1 3.4 1 1 1 3 3 3 0 Minor tail protein T BBP1_C PF15272.6 KFX96616.1 - 0.12 12.2 1.2 0.19 11.5 0.0 1.8 2 0 0 2 2 2 0 Spindle pole body component BBP1, C-terminal Acyl-CoA_dh_1 PF00441.24 KFX96617.1 - 6.5e-43 146.5 1.4 6.5e-43 146.5 1.4 1.5 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 KFX96617.1 - 1.6e-30 106.1 0.2 4.7e-30 104.6 0.1 1.9 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 KFX96617.1 - 1.2e-27 95.9 0.2 2.5e-27 94.9 0.2 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 KFX96617.1 - 1.3e-15 57.9 0.1 2.9e-15 56.7 0.1 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain HpaB_N PF11794.8 KFX96617.1 - 0.012 15.2 0.2 0.045 13.4 0.2 1.8 1 1 0 1 1 1 0 4-hydroxyphenylacetate 3-hydroxylase N terminal Carboxyl_trans PF01039.22 KFX96618.1 - 1.6e-136 455.8 0.1 2.1e-136 455.5 0.1 1.1 1 0 0 1 1 1 1 Carboxyl transferase domain Bot1p PF12298.8 KFX96619.1 - 6.9e-50 169.6 0.9 1.2e-49 168.8 0.9 1.4 1 0 0 1 1 1 1 Eukaryotic mitochondrial regulator protein DUF2052 PF09747.9 KFX96619.1 - 1.4e-22 80.8 17.0 1.9e-11 44.5 0.1 2.6 2 1 1 3 3 3 2 Coiled-coil domain containing protein (DUF2052) HTH_ParB PF17762.1 KFX96619.1 - 0.021 14.6 0.0 0.045 13.6 0.0 1.5 1 0 0 1 1 1 0 HTH domain found in ParB protein TnsD PF15978.5 KFX96619.1 - 0.071 12.1 0.2 0.17 10.8 0.0 1.6 2 0 0 2 2 2 0 Tn7-like transposition protein D Y_phosphatase3 PF13350.6 KFX96620.1 - 8.3e-62 209.2 0.0 9.4e-62 209.0 0.0 1.0 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase PF00102.27 KFX96620.1 - 3.4e-05 23.5 0.0 5.2e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase2 PF03162.13 KFX96620.1 - 0.0022 17.6 0.0 0.0042 16.7 0.0 1.5 1 0 0 1 1 1 1 Tyrosine phosphatase family Herpes_DNAp_acc PF04929.12 KFX96620.1 - 0.053 12.5 0.0 0.076 12.0 0.0 1.1 1 0 0 1 1 1 0 Herpes DNA replication accessory factor DUF3752 PF12572.8 KFX96639.1 - 3.8e-51 173.6 7.2 3.8e-51 173.6 7.2 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF3752) Dynamitin PF04912.14 KFX96639.1 - 0.043 13.2 0.3 0.048 13.0 0.3 1.1 1 0 0 1 1 1 0 Dynamitin FA_desaturase PF00487.24 KFX96648.1 - 3.2e-15 56.7 7.0 5.7e-15 55.8 7.0 1.5 1 1 0 1 1 1 1 Fatty acid desaturase DUF3474 PF11960.8 KFX96648.1 - 0.0012 19.1 0.0 0.017 15.3 0.0 2.4 2 1 0 2 2 2 1 Domain of unknown function (DUF3474) Inhibitor_I53 PF11714.8 KFX96649.1 - 0.078 13.2 0.1 0.13 12.5 0.1 1.3 1 0 0 1 1 1 0 Thrombin inhibitor Madanin Flagellin_IN PF07196.13 KFX96653.1 - 0.11 12.8 0.1 0.19 12.0 0.1 1.3 1 0 0 1 1 1 0 Flagellin hook IN motif FMO-like PF00743.19 KFX96655.1 - 6.9e-61 206.3 0.0 8.5e-61 206.0 0.0 1.0 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 KFX96655.1 - 2.7e-23 82.7 0.0 1.1e-19 70.9 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KFX96655.1 - 7.6e-12 45.1 0.0 1.7e-10 40.6 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KFX96655.1 - 7.7e-09 35.1 0.0 1.3e-07 31.2 0.0 2.2 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) IlvN PF07991.12 KFX96655.1 - 0.00047 19.8 0.0 0.11 12.1 0.0 2.3 2 0 0 2 2 2 2 Acetohydroxy acid isomeroreductase, NADPH-binding domain 2-Hacid_dh_C PF02826.19 KFX96655.1 - 0.0008 18.8 0.1 0.18 11.1 0.1 2.4 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_2 PF03446.15 KFX96655.1 - 0.0065 16.7 0.5 0.031 14.5 0.2 2.1 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase Pyr_redox PF00070.27 KFX96655.1 - 0.0076 16.8 0.9 0.84 10.2 0.0 3.1 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KFX96655.1 - 0.0089 16.0 0.0 0.21 11.5 0.0 2.6 2 1 0 2 2 2 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 KFX96655.1 - 0.017 15.3 0.0 0.034 14.4 0.0 1.5 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain NAD_binding_7 PF13241.6 KFX96655.1 - 0.021 15.3 0.0 9.5 6.7 0.0 2.3 2 0 0 2 2 2 0 Putative NAD(P)-binding UDPG_MGDP_dh_N PF03721.14 KFX96655.1 - 0.022 14.3 0.1 0.11 12.0 0.0 2.1 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Peptidase_M17_N PF02789.17 KFX96655.1 - 0.083 12.7 0.1 13 5.7 0.0 2.2 2 0 0 2 2 2 0 Cytosol aminopeptidase family, N-terminal domain GTP_EFTU PF00009.27 KFX96656.1 - 9.1e-57 191.7 0.0 1.4e-56 191.1 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_C PF00679.24 KFX96656.1 - 1.4e-13 50.7 0.0 4.2e-13 49.1 0.0 1.8 2 0 0 2 2 2 1 Elongation factor G C-terminus EFG_II PF14492.6 KFX96656.1 - 1.1e-08 35.0 0.0 2.3e-08 34.0 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II GTP_EFTU_D2 PF03144.25 KFX96656.1 - 1.4e-08 34.9 0.0 8.4e-08 32.5 0.0 2.3 3 0 0 3 3 3 1 Elongation factor Tu domain 2 EFG_IV PF03764.18 KFX96656.1 - 0.00011 22.0 0.0 0.00059 19.6 0.0 2.2 2 0 0 2 2 2 1 Elongation factor G, domain IV MMR_HSR1 PF01926.23 KFX96656.1 - 0.058 13.5 0.0 0.16 12.0 0.0 1.8 1 1 0 1 1 1 0 50S ribosome-binding GTPase PH PF00169.29 KFX96657.1 - 3.5e-13 50.0 0.1 5e-13 49.5 0.1 1.2 1 0 0 1 1 1 1 PH domain PH_8 PF15409.6 KFX96657.1 - 8.3e-06 26.0 0.1 1.4e-05 25.3 0.1 1.3 1 0 0 1 1 1 1 Pleckstrin homology domain PH_11 PF15413.6 KFX96657.1 - 3.8e-05 24.1 0.2 0.00087 19.7 0.2 2.2 1 1 0 1 1 1 1 Pleckstrin homology domain PH_9 PF15410.6 KFX96657.1 - 4.2e-05 23.9 0.1 0.0016 18.8 0.1 2.2 1 1 0 1 1 1 1 Pleckstrin homology domain PH_3 PF14593.6 KFX96657.1 - 0.00012 22.1 0.1 0.00019 21.5 0.1 1.3 1 0 0 1 1 1 1 PH domain Myosin_TH1 PF06017.13 KFX96657.1 - 0.12 12.1 0.1 0.17 11.5 0.1 1.2 1 0 0 1 1 1 0 Unconventional myosin tail, actin- and lipid-binding DUF4148 PF13663.6 KFX96659.1 - 2.5 8.3 5.2 13 6.1 5.2 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4148) TB2_DP1_HVA22 PF03134.19 KFX96664.1 - 1.4e-22 79.4 8.3 2.6e-22 78.5 8.3 1.4 1 0 0 1 1 1 1 TB2/DP1, HVA22 family HTH_Tnp_Tc5 PF03221.16 KFX96665.1 - 2.7e-05 24.1 0.1 5.5e-05 23.1 0.1 1.5 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain Sigma70_r4 PF04545.16 KFX96665.1 - 0.025 14.1 0.0 0.064 12.8 0.0 1.6 1 0 0 1 1 1 0 Sigma-70, region 4 HTH_Crp_2 PF13545.6 KFX96665.1 - 0.038 14.0 0.0 0.15 12.0 0.0 1.9 2 0 0 2 2 2 0 Crp-like helix-turn-helix domain DUF1013 PF06242.11 KFX96665.1 - 0.045 13.8 0.7 0.1 12.7 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1013) HTH_23 PF13384.6 KFX96665.1 - 0.11 12.4 0.0 0.38 10.6 0.0 1.9 2 0 0 2 2 2 0 Homeodomain-like domain HTH_Tnp_4 PF13613.6 KFX96665.1 - 0.14 11.9 0.0 0.26 11.0 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix of DDE superfamily endonuclease CENP-B_N PF04218.13 KFX96665.1 - 0.39 10.4 0.0 0.39 10.4 0.0 1.7 2 0 0 2 2 2 0 CENP-B N-terminal DNA-binding domain XRN_M PF17846.1 KFX96668.1 - 3.4e-101 339.4 6.7 5.4e-101 338.7 6.7 1.2 1 0 0 1 1 1 1 Xrn1 helical domain XRN_N PF03159.18 KFX96668.1 - 1.3e-96 322.8 0.1 2e-96 322.1 0.1 1.3 1 0 0 1 1 1 1 XRN 5'-3' exonuclease N-terminus XRN1_D1 PF18332.1 KFX96668.1 - 4.4e-76 254.9 0.0 8.7e-76 254.0 0.0 1.5 1 0 0 1 1 1 1 Exoribonuclease Xrn1 D1 domain XRN1_D2_D3 PF18334.1 KFX96668.1 - 1.4e-34 118.1 0.0 3.9e-34 116.7 0.0 1.8 1 0 0 1 1 1 1 Exoribonuclease Xrn1 D2/D3 domain SH3_12 PF18129.1 KFX96668.1 - 3.4e-25 87.9 0.6 7.3e-25 86.9 0.6 1.6 1 0 0 1 1 1 1 Xrn1 SH3-like domain Xrn1_D3 PF18194.1 KFX96668.1 - 6.2e-09 35.8 0.1 1.4e-08 34.7 0.1 1.6 1 0 0 1 1 1 1 Exoribonuclease 1 Domain-3 MPM1 PF17234.2 KFX96668.1 - 0.4 10.9 3.8 0.95 9.7 3.8 1.5 1 0 0 1 1 1 0 Mitochondrial peculiar membrane protein 1 CAF1C_H4-bd PF12265.8 KFX96669.1 - 6.2e-28 96.9 1.3 5.6e-27 93.8 1.2 2.5 2 0 0 2 2 2 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex WD40 PF00400.32 KFX96669.1 - 1.6e-27 95.2 9.3 1.8e-05 25.4 0.1 6.2 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFX96669.1 - 1.3e-06 28.6 1.1 0.15 12.4 0.1 4.3 2 1 3 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Peptidase_C93 PF06035.11 KFX96670.1 - 0.033 14.0 0.2 0.054 13.3 0.2 1.3 1 0 0 1 1 1 0 Bacterial transglutaminase-like cysteine proteinase BTLCP Med5 PF08689.10 KFX96676.1 - 4.8e-83 279.7 0.0 1.4e-82 278.2 0.0 1.6 1 1 0 1 1 1 1 Mediator complex subunit Med5 ORC5_C PF14630.6 KFX96677.1 - 1.2e-80 271.0 0.0 1.4e-80 270.8 0.0 1.0 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 5 C-terminus PAF PF15715.5 KFX96677.1 - 0.081 13.5 2.0 1.7 9.3 0.1 2.2 2 0 0 2 2 2 0 PCNA-associated factor histone like domain VEFS-Box PF09733.9 KFX96678.1 - 0.00055 19.8 2.5 0.00055 19.8 2.5 2.7 3 0 0 3 3 3 1 VEFS-Box of polycomb protein PHD PF00628.29 KFX96678.1 - 0.92 9.5 4.9 2.3 8.2 4.9 1.7 1 0 0 1 1 1 0 PHD-finger Pyr_redox_2 PF07992.14 KFX96683.1 - 5.4e-44 150.6 0.0 8.1e-44 150.0 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase CLTH PF10607.9 KFX96683.1 - 3.6e-32 111.3 0.0 7.6e-32 110.2 0.0 1.5 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain Pyr_redox PF00070.27 KFX96683.1 - 3.9e-13 49.8 0.0 8.5e-10 39.1 0.0 2.8 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase LisH PF08513.11 KFX96683.1 - 3.6e-07 29.9 0.0 6.6e-07 29.1 0.0 1.5 1 0 0 1 1 1 1 LisH EF-hand_1 PF00036.32 KFX96683.1 - 6e-06 25.4 0.3 1.5e-05 24.2 0.3 1.8 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.6 KFX96683.1 - 0.00021 21.0 0.3 0.00059 19.6 0.3 1.8 1 0 0 1 1 1 1 EF-hand domain EF-hand_5 PF13202.6 KFX96683.1 - 0.0018 17.7 0.3 0.0035 16.8 0.3 1.5 1 0 0 1 1 1 1 EF hand EF-hand_7 PF13499.6 KFX96683.1 - 0.0018 18.7 0.1 0.0061 17.0 0.1 2.0 1 0 0 1 1 1 1 EF-hand domain pair Pyr_redox_3 PF13738.6 KFX96683.1 - 0.066 12.5 0.2 0.81 8.9 0.4 2.3 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Methyltransf_2 PF00891.18 KFX96686.1 - 1.5e-19 70.1 0.0 2.1e-19 69.7 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase domain Dimerisation2 PF16864.5 KFX96686.1 - 0.0027 17.6 0.0 0.0063 16.5 0.0 1.6 1 0 0 1 1 1 1 Dimerisation domain TrmB PF01978.19 KFX96686.1 - 0.0039 17.0 0.0 0.0078 16.1 0.0 1.5 1 0 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB Dimerisation PF08100.11 KFX96686.1 - 0.024 14.6 0.1 0.15 12.1 0.1 2.5 2 0 0 2 2 2 0 Dimerisation domain Rrf2 PF02082.20 KFX96686.1 - 0.031 14.6 0.1 0.15 12.4 0.1 2.2 2 1 0 2 2 2 0 Transcriptional regulator SWIRM PF04433.17 KFX96686.1 - 0.11 12.8 0.0 0.47 10.8 0.0 2.1 2 0 0 2 2 2 0 SWIRM domain NinB PF05772.12 KFX96686.1 - 0.18 11.6 0.0 0.36 10.6 0.0 1.5 1 0 0 1 1 1 0 NinB protein Glyco_hydro_28 PF00295.17 KFX96688.1 - 5.2e-98 328.1 20.4 6.1e-98 327.9 20.4 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 Pectate_lyase PF03211.13 KFX96688.1 - 0.24 10.9 9.5 0.8 9.2 9.5 2.0 1 1 0 1 1 1 0 Pectate lyase MFS_1 PF07690.16 KFX96689.1 - 5e-45 154.0 57.1 2.2e-44 151.8 54.8 2.6 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 KFX96689.1 - 1.7e-23 83.0 27.4 2.5e-23 82.4 27.4 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 KFX96689.1 - 1.1e-12 47.6 14.9 1.1e-12 47.6 14.9 2.5 2 0 0 2 2 2 2 Sugar (and other) transporter Prenyltransf PF01255.19 KFX96690.1 - 7.3e-72 241.5 0.0 5.2e-69 232.2 0.0 2.7 3 0 0 3 3 3 2 Putative undecaprenyl diphosphate synthase Terpene_synth_C PF03936.16 KFX96691.1 - 0.0044 16.4 0.0 0.0083 15.5 0.0 1.4 1 0 0 1 1 1 1 Terpene synthase family, metal binding domain PPP1R35_C PF15503.6 KFX96692.1 - 0.17 11.7 0.0 0.22 11.3 0.0 1.3 1 0 0 1 1 1 0 Protein phosphatase 1 regulatory subunit 35 C-terminus Crystall_3 PF08964.10 KFX96693.1 - 0.00022 21.3 0.5 0.022 14.9 0.0 3.0 3 0 0 3 3 3 1 Beta/Gamma crystallin Crystall PF00030.19 KFX96693.1 - 0.01 16.0 0.6 2 8.7 0.0 2.9 3 0 0 3 3 3 0 Beta/Gamma crystallin Sugar_tr PF00083.24 KFX96725.1 - 1.5e-45 155.9 1.7 2.3e-45 155.3 1.7 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KFX96725.1 - 1.6e-28 99.6 35.4 1.7e-28 99.6 34.4 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily MFS_1_like PF12832.7 KFX96725.1 - 0.00078 18.4 1.2 0.14 11.0 0.1 2.8 2 1 0 2 2 2 2 MFS_1 like family ATG22 PF11700.8 KFX96725.1 - 0.0042 15.8 8.2 0.024 13.3 4.1 2.3 2 0 0 2 2 2 2 Vacuole effluxer Atg22 like LacY_symp PF01306.19 KFX96725.1 - 0.71 8.6 6.9 4.1 6.1 6.1 2.1 1 1 0 1 1 1 0 LacY proton/sugar symporter DUF2236 PF09995.9 KFX96726.1 - 1e-27 97.8 0.0 1.6e-27 97.2 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2236) DUF2520 PF10728.9 KFX96726.1 - 0.012 15.4 0.0 0.021 14.6 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF2520) Ank_2 PF12796.7 KFX96728.1 - 4.5e-81 267.5 18.8 4.2e-14 52.9 0.0 6.4 1 1 8 9 9 9 9 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KFX96728.1 - 7.4e-56 185.8 2.2 1.5e-09 38.2 0.0 10.1 2 2 8 11 11 11 9 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFX96728.1 - 4.5e-48 155.6 1.5 0.0042 17.5 0.0 13.1 13 0 0 13 13 13 11 Ankyrin repeat Ank PF00023.30 KFX96728.1 - 1.8e-35 119.8 15.9 0.028 14.9 0.0 12.9 10 2 2 12 12 12 9 Ankyrin repeat Ank_5 PF13857.6 KFX96728.1 - 6e-35 118.8 11.7 9.5e-07 29.0 0.1 11.5 2 2 11 13 13 13 9 Ankyrin repeats (many copies) DUF4646 PF15496.6 KFX96728.1 - 9.4e-05 23.0 0.2 0.00049 20.7 0.2 2.1 1 1 0 1 1 1 1 Domain of unknown function (DUF4646) DUF249 PF03158.13 KFX96728.1 - 0.025 14.3 0.0 0.066 12.9 0.0 1.7 1 0 0 1 1 1 0 Multigene family 530 protein Shigella_OspC PF06128.11 KFX96728.1 - 0.071 12.8 0.1 35 4.0 0.0 4.2 5 0 0 5 5 5 0 Shigella flexneri OspC protein Hydrolase_4 PF12146.8 KFX96729.1 - 0.0012 18.1 0.0 0.0019 17.5 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 PAF-AH_p_II PF03403.13 KFX96729.1 - 0.24 9.9 0.2 1.9 6.9 0.0 2.0 1 1 1 2 2 2 0 Platelet-activating factor acetylhydrolase, isoform II PHY PF00360.20 KFX96730.1 - 4.1e-26 91.4 0.0 1.1e-25 90.0 0.0 1.7 2 0 0 2 2 2 1 Phytochrome region Response_reg PF00072.24 KFX96730.1 - 4.3e-17 62.3 0.0 2.6e-16 59.8 0.0 2.2 1 1 0 1 1 1 1 Response regulator receiver domain HATPase_c PF02518.26 KFX96730.1 - 1.3e-16 61.1 0.1 3.1e-16 59.9 0.1 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase GAF PF01590.26 KFX96730.1 - 3.7e-13 50.2 0.0 9.2e-13 49.0 0.0 1.7 1 0 0 1 1 1 1 GAF domain HisKA PF00512.25 KFX96730.1 - 1.8e-12 47.1 0.7 5.5e-12 45.6 0.7 1.8 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PAS_2 PF08446.11 KFX96730.1 - 8e-07 29.7 0.0 2.8e-06 28.0 0.0 2.0 1 0 0 1 1 1 1 PAS fold HATPase_c_3 PF13589.6 KFX96730.1 - 0.021 14.7 0.1 0.058 13.2 0.1 1.7 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase GNAT_acetyltr_2 PF13718.6 KFX96730.1 - 0.056 12.8 0.0 3.9 6.8 0.0 2.5 2 0 0 2 2 2 0 GNAT acetyltransferase 2 WSC PF01822.19 KFX96732.1 - 3.3e-30 104.1 17.8 2.2e-17 63.0 6.0 3.4 3 0 0 3 3 3 2 WSC domain Ank_2 PF12796.7 KFX96733.1 - 1.8e-09 38.0 0.0 5.4e-09 36.5 0.0 1.9 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KFX96733.1 - 2.4e-09 37.6 0.0 8.1e-08 32.7 0.0 3.0 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 KFX96733.1 - 0.00042 20.6 0.0 0.041 14.2 0.0 2.7 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank PF00023.30 KFX96733.1 - 0.00061 20.1 0.6 1.2 9.7 0.0 3.8 3 1 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.6 KFX96733.1 - 0.02 15.4 0.0 57 4.8 0.0 4.4 4 0 0 4 4 4 0 Ankyrin repeat Wzz PF02706.15 KFX96733.1 - 0.06 13.6 0.9 0.23 11.8 0.0 2.5 2 0 0 2 2 2 0 Chain length determinant protein DUF1961 PF09224.11 KFX96739.1 - 2.6e-97 324.4 0.0 2.9e-97 324.2 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1961) Sugar_tr PF00083.24 KFX96740.1 - 1.1e-71 242.1 29.0 1.2e-71 241.9 29.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KFX96740.1 - 1e-13 51.0 30.7 1e-13 51.0 30.7 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily MFS_1_like PF12832.7 KFX96740.1 - 0.65 8.8 25.4 0.12 11.2 9.9 2.4 2 1 0 2 2 2 0 MFS_1 like family AMP-binding PF00501.28 KFX96743.1 - 1.3e-60 205.2 0.0 1.9e-60 204.6 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme Condensation PF00668.20 KFX96743.1 - 1.9e-24 86.2 0.0 5.5e-24 84.7 0.0 1.7 1 1 0 1 1 1 1 Condensation domain PP-binding PF00550.25 KFX96743.1 - 2.5e-07 31.0 0.0 7e-07 29.5 0.0 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site AMP-binding_C PF13193.6 KFX96743.1 - 0.00031 21.7 0.1 0.0011 19.9 0.1 2.1 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain FAD_binding_3 PF01494.19 KFX96749.1 - 4.4e-17 62.4 1.0 8.2e-16 58.2 1.0 2.5 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 KFX96749.1 - 0.012 15.8 0.0 0.053 13.8 0.0 2.0 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain DUF4244 PF14029.6 KFX96751.1 - 0.4 10.2 3.0 0.45 10.0 1.8 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF4244) Orn_Arg_deC_N PF02784.16 KFX96752.1 - 1.4e-67 227.7 0.0 1.8e-67 227.3 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.22 KFX96752.1 - 2.2e-15 56.7 0.0 2.5e-15 56.5 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain TTL PF03133.15 KFX96755.1 - 1.2e-39 136.3 0.0 1.7e-39 135.8 0.0 1.1 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 KFX96755.1 - 7.6e-05 22.1 0.0 0.00014 21.2 0.0 1.4 1 0 0 1 1 1 1 YheC/D like ATP-grasp PaaX_C PF08223.11 KFX96755.1 - 0.15 12.3 0.0 0.4 11.0 0.0 1.6 1 0 0 1 1 1 0 PaaX-like protein C-terminal domain Mito_fiss_reg PF05308.11 KFX96756.1 - 0.07 13.2 5.2 0.091 12.8 5.2 1.2 1 0 0 1 1 1 0 Mitochondrial fission regulator CAP_N PF01213.19 KFX96756.1 - 0.11 12.0 10.7 0.15 11.5 10.7 1.2 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal AAA_12 PF13087.6 KFX96758.1 - 1.3e-39 136.0 0.3 2.1e-39 135.2 0.3 1.4 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 KFX96758.1 - 1.7e-23 83.7 0.0 4.7e-23 82.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain DUF2075 PF09848.9 KFX96758.1 - 1.1e-07 31.5 0.3 0.0016 17.8 0.0 2.6 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2075) zf-CCCH_4 PF18044.1 KFX96758.1 - 6e-07 29.1 2.6 1.1e-06 28.2 2.6 1.5 1 0 0 1 1 1 1 CCCH-type zinc finger AAA_19 PF13245.6 KFX96758.1 - 2.1e-06 28.1 0.0 1.2e-05 25.6 0.0 2.3 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 KFX96758.1 - 0.00091 19.0 0.1 0.0027 17.4 0.0 1.9 2 0 0 2 2 2 1 AAA domain zf-CCCH PF00642.24 KFX96758.1 - 0.0066 16.3 1.6 0.012 15.5 1.6 1.5 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) ResIII PF04851.15 KFX96758.1 - 0.093 12.7 0.0 0.31 11.0 0.0 1.8 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit PhoH PF02562.16 KFX96758.1 - 0.1 12.0 0.0 0.25 10.8 0.0 1.6 1 0 0 1 1 1 0 PhoH-like protein Torus PF16131.5 KFX96758.1 - 0.11 13.2 0.0 0.34 11.6 0.0 1.9 1 0 0 1 1 1 0 Torus domain AAA_22 PF13401.6 KFX96758.1 - 0.11 12.7 0.1 0.81 10.0 0.0 2.6 2 0 0 2 2 2 0 AAA domain zf_CCCH_4 PF18345.1 KFX96758.1 - 0.14 12.3 3.5 0.34 11.0 3.5 1.7 1 0 0 1 1 1 0 Zinc finger domain Mg_chelatase PF01078.21 KFX96758.1 - 0.16 11.3 0.0 0.32 10.4 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI VSG_B PF13206.6 KFX96763.1 - 0.46 9.7 2.3 0.74 9.0 2.3 1.3 1 0 0 1 1 1 0 Trypanosomal VSG domain DUF1866 PF08952.11 KFX96776.1 - 0.059 13.2 0.1 0.07 13.0 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1866) DcpS_C PF11969.8 KFX96777.1 - 0.0099 16.3 0.0 0.012 16.1 0.0 1.2 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding GFO_IDH_MocA PF01408.22 KFX96783.1 - 9.5e-16 58.7 0.0 1.5e-15 58.1 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 KFX96783.1 - 0.056 13.4 0.0 0.11 12.5 0.0 1.5 1 0 0 1 1 1 0 Oxidoreductase family, C-terminal alpha/beta domain DUF3425 PF11905.8 KFX96784.1 - 1.7e-20 73.3 0.4 3.6e-20 72.2 0.0 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF3425) RPN6_N PF18055.1 KFX96787.1 - 3.3e-48 162.9 1.9 3.3e-48 162.9 1.9 1.3 2 0 0 2 2 2 1 26S proteasome regulatory subunit RPN6 N-terminal domain AAA_6 PF12774.7 KFX96787.1 - 0.017 14.1 0.3 0.02 13.9 0.3 1.1 1 0 0 1 1 1 0 Hydrolytic ATP binding site of dynein motor region TPR_14 PF13428.6 KFX96787.1 - 0.021 15.6 0.9 7 7.8 0.0 3.3 2 1 1 3 3 3 0 Tetratricopeptide repeat DUF410 PF04190.13 KFX96787.1 - 0.031 14.1 0.3 0.079 12.8 0.1 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF410) Med2 PF11214.8 KFX96787.1 - 0.051 13.7 0.2 0.098 12.8 0.2 1.5 1 0 0 1 1 1 0 Mediator complex subunit 2 TPR_7 PF13176.6 KFX96787.1 - 0.094 12.8 0.0 0.88 9.7 0.0 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat Sof1 PF04158.14 KFX96788.1 - 7.7e-30 103.0 18.9 1.4e-29 102.2 18.9 1.5 1 0 0 1 1 1 1 Sof1-like domain WD40 PF00400.32 KFX96788.1 - 3.1e-27 94.3 6.2 3.3e-05 24.6 0.1 6.6 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFX96788.1 - 7.6e-10 39.0 0.1 0.028 14.7 0.0 4.3 2 1 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain BBS2_Mid PF14783.6 KFX96788.1 - 0.0002 21.4 0.4 3.5 7.7 0.0 4.8 2 2 4 6 6 6 1 Ciliary BBSome complex subunit 2, middle region Ge1_WD40 PF16529.5 KFX96788.1 - 0.0019 17.3 0.0 0.059 12.3 0.0 2.8 1 1 2 3 3 3 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Cytochrom_D1 PF02239.16 KFX96788.1 - 0.0033 16.0 0.4 0.091 11.3 0.1 2.8 3 1 0 3 3 3 1 Cytochrome D1 heme domain DUF3288 PF11691.8 KFX96788.1 - 0.067 13.2 0.6 0.18 11.8 0.6 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3288) TauD PF02668.16 KFX96789.1 - 1.9e-44 152.5 0.0 2.5e-44 152.1 0.0 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Plasmod_MYXSPDY PF07981.11 KFX96789.1 - 0.13 12.3 0.3 0.13 12.3 0.3 1.7 2 0 0 2 2 2 0 Plasmodium repeat_MYXSPDY DPPIV_N PF00930.21 KFX96790.1 - 1.2e-113 379.5 0.8 1.6e-113 379.1 0.8 1.2 1 0 0 1 1 1 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Peptidase_S9 PF00326.21 KFX96790.1 - 3.7e-56 189.9 2.4 7.5e-56 188.9 2.4 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Peptidase_S15 PF02129.18 KFX96790.1 - 2.9e-07 30.4 1.2 6.5e-06 25.9 0.4 2.3 1 1 1 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) Hydrolase_4 PF12146.8 KFX96790.1 - 0.0023 17.2 0.9 0.19 10.9 0.1 2.3 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KFX96790.1 - 0.011 16.3 3.1 0.23 12.0 0.7 2.6 1 1 1 2 2 2 0 Alpha/beta hydrolase family AXE1 PF05448.12 KFX96790.1 - 0.022 13.5 0.0 0.34 9.5 0.0 2.2 1 1 0 1 1 1 0 Acetyl xylan esterase (AXE1) Abhydrolase_1 PF00561.20 KFX96790.1 - 0.041 13.5 0.1 0.096 12.3 0.1 1.6 1 0 0 1 1 1 0 alpha/beta hydrolase fold DLH PF01738.18 KFX96790.1 - 0.066 12.8 0.0 0.33 10.5 0.0 2.0 1 1 0 1 1 1 0 Dienelactone hydrolase family PAF-AH_p_II PF03403.13 KFX96790.1 - 0.11 11.0 0.0 0.67 8.4 0.0 1.9 2 0 0 2 2 2 0 Platelet-activating factor acetylhydrolase, isoform II SpoIIE PF07228.12 KFX96791.1 - 6e-09 36.1 0.3 3.5e-08 33.6 0.3 2.0 1 1 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) PP2C_2 PF13672.6 KFX96791.1 - 3.4e-07 30.1 0.7 6.1e-07 29.3 0.7 1.4 1 1 0 1 1 1 1 Protein phosphatase 2C PP2C PF00481.21 KFX96791.1 - 4e-06 26.7 0.1 0.043 13.4 0.0 2.4 2 0 0 2 2 2 2 Protein phosphatase 2C Ribosomal_L21p PF00829.21 KFX96792.1 - 1.1e-08 35.2 0.0 1.6e-08 34.7 0.0 1.3 1 0 0 1 1 1 1 Ribosomal prokaryotic L21 protein SNRNP27 PF08648.12 KFX96794.1 - 0.11 12.5 0.1 0.24 11.5 0.1 1.5 1 0 0 1 1 1 0 U4/U6.U5 small nuclear ribonucleoproteins Pribosyl_synth PF14572.6 KFX96795.1 - 7.9e-42 143.4 0.8 6.1e-36 124.2 0.3 2.5 1 1 1 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran_N PF13793.6 KFX96795.1 - 3.1e-31 107.7 0.0 7.2e-31 106.5 0.0 1.6 1 0 0 1 1 1 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyltran PF00156.27 KFX96795.1 - 3e-13 49.6 0.3 4.8e-13 48.9 0.3 1.3 1 0 0 1 1 1 1 Phosphoribosyl transferase domain RNA_pol_Rpb4 PF03874.16 KFX96796.1 - 4.4e-18 65.8 0.0 6.3e-18 65.3 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb4 Ras PF00071.22 KFX96797.1 - 4.1e-17 62.3 0.0 5.9e-17 61.7 0.0 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFX96797.1 - 5.1e-05 23.5 0.0 0.0001 22.5 0.0 1.5 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase NACHT PF05729.12 KFX96797.1 - 0.0021 18.0 0.0 0.0039 17.1 0.0 1.4 1 0 0 1 1 1 1 NACHT domain Arf PF00025.21 KFX96797.1 - 0.0022 17.5 0.0 0.037 13.5 0.0 2.0 2 0 0 2 2 2 1 ADP-ribosylation factor family RNA_helicase PF00910.22 KFX96797.1 - 0.027 14.8 0.0 0.057 13.8 0.0 1.6 1 1 0 1 1 1 0 RNA helicase G-alpha PF00503.20 KFX96797.1 - 0.09 11.9 0.0 0.16 11.1 0.0 1.4 1 0 0 1 1 1 0 G-protein alpha subunit MMR_HSR1 PF01926.23 KFX96797.1 - 0.12 12.4 0.0 0.43 10.7 0.0 1.9 1 1 0 1 1 1 0 50S ribosome-binding GTPase ABC_tran PF00005.27 KFX96797.1 - 0.16 12.5 0.0 0.29 11.6 0.0 1.4 1 0 0 1 1 1 0 ABC transporter DUF2075 PF09848.9 KFX96797.1 - 0.17 11.1 0.1 1.1 8.4 0.0 1.9 1 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) PseudoU_synth_1 PF01416.20 KFX96798.1 - 2.6e-35 121.2 0.0 8.3e-34 116.3 0.0 2.6 2 0 0 2 2 2 1 tRNA pseudouridine synthase zf-C2H2 PF00096.26 KFX96821.1 - 1.3e-20 72.6 26.0 0.00011 22.5 2.6 4.8 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KFX96821.1 - 1.9e-18 65.9 28.2 1.8e-06 28.1 1.2 5.6 6 0 0 6 6 5 4 Zinc-finger double domain zf-C2H2_4 PF13894.6 KFX96821.1 - 1.9e-11 43.7 26.7 0.005 17.6 1.9 5.0 5 0 0 5 5 4 4 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFX96821.1 - 6e-07 29.6 0.4 0.41 11.0 0.0 4.3 4 0 0 4 4 4 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KFX96821.1 - 1e-05 25.7 8.9 0.1 13.0 0.0 4.1 4 0 0 4 4 4 3 Zinc-finger of C2H2 type DUF2477 PF10631.9 KFX96821.1 - 0.011 16.4 4.0 0.011 16.4 4.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF2477) zf-C2H2_11 PF16622.5 KFX96821.1 - 0.013 15.3 1.8 0.013 15.3 1.8 3.2 3 0 0 3 3 3 0 zinc-finger C2H2-type FOXP-CC PF16159.5 KFX96821.1 - 0.064 13.9 1.8 8.1 7.2 0.2 3.0 2 1 1 3 3 3 0 FOXP coiled-coil domain zf_UBZ PF18439.1 KFX96821.1 - 0.1 12.2 2.5 0.87 9.2 0.2 2.9 3 0 0 3 3 3 0 Ubiquitin-Binding Zinc Finger BolA PF01722.18 KFX96821.1 - 0.11 12.8 3.8 4.7 7.6 0.0 2.7 3 0 0 3 3 3 0 BolA-like protein zf-C2H2_aberr PF17017.5 KFX96821.1 - 0.96 9.6 2.7 4.5 7.4 0.3 2.2 1 1 0 2 2 2 0 Aberrant zinc-finger zf-C2HC_2 PF13913.6 KFX96821.1 - 1.4 8.9 8.4 2.6 8.1 1.1 3.5 3 0 0 3 3 3 0 zinc-finger of a C2HC-type IBR PF01485.21 KFX96821.1 - 1.7 8.9 8.9 4.6 7.5 0.6 3.0 1 1 2 3 3 3 0 IBR domain, a half RING-finger domain zf-LYAR PF08790.11 KFX96821.1 - 3.6 7.6 5.7 6.5 6.8 0.1 3.4 4 0 0 4 4 4 0 LYAR-type C2HC zinc finger FBPase PF00316.20 KFX96822.1 - 8.6e-71 237.3 0.1 1.2e-70 236.9 0.1 1.2 1 0 0 1 1 1 1 Fructose-1-6-bisphosphatase, N-terminal domain Usp PF00582.26 KFX96824.1 - 6.2e-24 85.1 0.8 9.1e-17 61.9 0.0 2.5 2 0 0 2 2 2 2 Universal stress protein family Pkinase PF00069.25 KFX96826.1 - 6.2e-48 163.5 0.0 8.7e-48 163.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFX96826.1 - 5.5e-30 104.5 0.0 7.9e-30 104.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase FTA2 PF13095.6 KFX96826.1 - 0.00045 19.9 0.0 0.36 10.4 0.0 2.2 2 0 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 KFX96826.1 - 0.001 19.0 0.0 0.0027 17.6 0.0 1.6 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 KFX96826.1 - 0.003 17.0 0.0 0.0048 16.3 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 KFX96826.1 - 0.02 14.2 0.0 0.2 10.9 0.0 2.0 2 0 0 2 2 2 0 Kinase-like Haspin_kinase PF12330.8 KFX96826.1 - 0.092 11.7 0.0 0.15 11.0 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain HOOK PF05622.12 KFX96827.1 - 3.6e-19 68.4 72.7 6.3e-14 51.1 73.0 3.2 2 1 0 2 2 2 2 HOOK protein GFO_IDH_MocA PF01408.22 KFX96827.1 - 1.4e-15 58.2 0.3 5.3e-15 56.3 0.3 2.0 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold ZapB PF06005.12 KFX96827.1 - 0.0053 17.2 2.8 0.0053 17.2 2.8 9.0 5 2 3 8 8 8 2 Cell division protein ZapB PKcGMP_CC PF16808.5 KFX96827.1 - 0.045 13.6 13.1 0.089 12.7 1.7 4.4 3 0 0 3 3 3 0 Coiled-coil N-terminus of cGMP-dependent protein kinase Bin3 PF06859.12 KFX96827.1 - 4.1 8.1 8.3 1.1 9.9 3.3 2.7 2 1 0 2 2 2 0 Bicoid-interacting protein 3 (Bin3) CENP-B_dimeris PF09026.10 KFX96835.1 - 0.025 15.0 5.0 0.042 14.2 5.0 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Pes-10 PF07149.11 KFX96835.1 - 0.11 11.5 3.4 0.11 11.5 3.4 1.0 1 0 0 1 1 1 0 Pes-10 NOA36 PF06524.12 KFX96835.1 - 0.19 11.0 6.1 0.21 10.9 6.1 1.2 1 0 0 1 1 1 0 NOA36 protein Sporozoite_P67 PF05642.11 KFX96835.1 - 0.35 8.9 3.9 0.33 9.0 3.9 1.0 1 0 0 1 1 1 0 Sporozoite P67 surface antigen DNA_pol_phi PF04931.13 KFX96835.1 - 1.2 7.1 4.3 1.1 7.3 4.3 1.0 1 0 0 1 1 1 0 DNA polymerase phi MFS_1 PF07690.16 KFX96837.1 - 2.6e-33 115.4 28.2 2.6e-33 115.4 28.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF3522 PF12036.8 KFX96837.1 - 0.2 11.9 4.7 0.63 10.3 0.0 2.8 2 2 1 3 3 3 0 Protein of unknown function (DUF3522) Kinesin PF00225.23 KFX96839.1 - 7.2e-93 311.1 0.0 1.2e-92 310.4 0.0 1.2 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 KFX96839.1 - 7.9e-20 71.3 0.0 3.1e-19 69.4 0.0 2.0 2 0 0 2 2 2 1 Microtubule binding PKcGMP_CC PF16808.5 KFX96839.1 - 0.0082 16.0 3.6 0.53 10.2 0.6 2.8 2 0 0 2 2 2 2 Coiled-coil N-terminus of cGMP-dependent protein kinase FlxA PF14282.6 KFX96839.1 - 0.042 13.8 0.4 0.14 12.1 0.4 1.9 1 0 0 1 1 1 0 FlxA-like protein RCC1 PF00415.18 KFX96840.1 - 4.8e-57 190.4 0.9 1.1e-08 35.5 0.1 7.6 7 1 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 KFX96840.1 - 6.5e-32 108.7 28.6 2.1e-09 36.9 0.2 7.1 6 1 1 7 7 7 6 Regulator of chromosome condensation (RCC1) repeat MFS_1 PF07690.16 KFX96841.1 - 1.5e-25 89.9 49.7 6.9e-15 54.8 28.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 KFX96841.1 - 1.2e-05 24.4 15.8 0.00034 19.6 0.7 2.6 2 1 0 2 2 2 2 MFS_1 like family AIM3 PF17096.5 KFX96842.1 - 0.00053 20.9 1.9 0.00072 20.4 1.9 1.2 1 0 0 1 1 1 1 Altered inheritance of mitochondria protein 3 DUF4887 PF16228.5 KFX96842.1 - 0.014 15.5 17.9 0.019 15.1 17.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4887) Herpes_UL32 PF06070.11 KFX96842.1 - 2.1 6.0 4.3 2.3 5.9 4.3 1.0 1 0 0 1 1 1 0 Herpesvirus large structural phosphoprotein UL32 ApbA PF02558.16 KFX96843.1 - 1.9e-25 89.3 0.0 2.8e-25 88.7 0.0 1.2 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA ApbA_C PF08546.11 KFX96843.1 - 1.6e-23 83.2 0.1 4.6e-23 81.8 0.0 1.7 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA C terminal COQ9 PF08511.11 KFX96855.1 - 4.8e-25 87.1 0.2 1e-24 86.1 0.0 1.7 2 0 0 2 2 2 1 COQ9 Amidase PF01425.21 KFX96856.1 - 1.2e-101 340.9 0.0 1.6e-101 340.5 0.0 1.2 1 0 0 1 1 1 1 Amidase DUF807 PF05660.11 KFX96856.1 - 0.074 13.0 0.1 0.16 11.9 0.1 1.5 1 0 0 1 1 1 0 Coxiella burnetii protein of unknown function (DUF807) 2OG-FeII_Oxy_2 PF13532.6 KFX96857.1 - 6.8e-33 114.5 0.0 9.1e-32 110.8 0.0 2.0 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Pkinase PF00069.25 KFX96858.1 - 3.1e-71 239.8 0.0 3.8e-71 239.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFX96858.1 - 5.6e-31 107.8 0.0 7.1e-31 107.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KFX96858.1 - 0.0022 17.4 0.0 0.0043 16.4 0.0 1.4 1 1 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 KFX96858.1 - 0.0025 16.8 0.0 0.02 13.8 0.0 1.9 2 0 0 2 2 2 1 Haspin like kinase domain APH PF01636.23 KFX96858.1 - 0.0069 16.3 0.1 0.013 15.5 0.1 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 KFX96858.1 - 0.022 13.8 0.1 0.035 13.1 0.1 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 Kdo PF06293.14 KFX96858.1 - 0.18 11.2 0.1 0.43 9.9 0.0 1.5 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF2796 PF10986.8 KFX96859.1 - 0.011 15.7 1.7 0.016 15.2 1.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2796) SPX PF03105.19 KFX96859.1 - 0.031 14.2 2.7 0.039 13.9 2.7 1.1 1 0 0 1 1 1 0 SPX domain XRCC4 PF06632.12 KFX96859.1 - 0.039 12.8 1.9 0.054 12.3 1.9 1.1 1 0 0 1 1 1 0 DNA double-strand break repair and V(D)J recombination protein XRCC4 Fig1 PF12351.8 KFX96859.1 - 0.17 11.8 0.2 4.6 7.1 0.0 2.3 2 0 0 2 2 2 0 Ca2+ regulator and membrane fusion protein Fig1 WD40 PF00400.32 KFX96869.1 - 5.2e-05 23.9 12.9 0.99 10.4 0.0 6.3 6 0 0 6 6 6 3 WD domain, G-beta repeat DUF971 PF06155.12 KFX96869.1 - 0.11 13.2 0.0 0.34 11.6 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF971) Glyco_hydro_43 PF04616.14 KFX96870.1 - 1.7e-33 116.2 4.2 2.4e-33 115.7 4.2 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 GH43_C2 PF17851.1 KFX96870.1 - 4.4e-24 85.3 0.0 7.2e-24 84.6 0.0 1.4 1 0 0 1 1 1 1 Beta xylosidase C-terminal Concanavalin A-like domain Glyco_hydro_10 PF00331.20 KFX96871.1 - 1.5e-100 336.4 0.0 1.7e-100 336.2 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 Glyco_hydro_42 PF02449.15 KFX96871.1 - 0.0095 15.3 0.1 0.069 12.5 0.0 1.9 1 1 1 2 2 2 1 Beta-galactosidase Beta-prism_lec PF16458.5 KFX96871.1 - 0.05 13.6 0.2 0.095 12.7 0.2 1.4 1 0 0 1 1 1 0 Beta-prism lectin ATP-synt_DE_N PF02823.16 KFX96871.1 - 0.1 12.5 0.0 0.21 11.5 0.0 1.5 1 0 0 1 1 1 0 ATP synthase, Delta/Epsilon chain, beta-sandwich domain Glyco_hydro_43 PF04616.14 KFX96872.1 - 3e-53 181.0 5.4 3e-53 181.0 5.4 1.8 2 0 0 2 2 2 1 Glycosyl hydrolases family 43 CBM_6 PF03422.15 KFX96872.1 - 4.2e-38 130.5 4.4 9.6e-38 129.3 4.4 1.6 1 0 0 1 1 1 1 Carbohydrate binding module (family 6) DUF5010_C PF18099.1 KFX96872.1 - 4.7e-09 36.4 1.0 1e-08 35.2 1.0 1.6 1 0 0 1 1 1 1 DUF5010 C-terminal domain Glyco_hydro_32N PF00251.20 KFX96872.1 - 3.9e-05 23.4 2.0 6e-05 22.7 2.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 N-terminal domain Glyco_hydro_62 PF03664.13 KFX96873.1 - 4.9e-156 518.0 15.7 5.7e-156 517.8 15.7 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 62 Melibiase_2 PF16499.5 KFX96874.1 - 9.9e-56 189.0 6.6 3.3e-55 187.3 6.6 1.8 1 1 0 1 1 1 1 Alpha galactosidase A Melibiase_C PF17801.1 KFX96874.1 - 8.7e-09 35.3 0.0 1.5e-06 28.2 0.0 2.7 2 0 0 2 2 2 2 Alpha galactosidase C-terminal beta sandwich domain Melibiase PF02065.18 KFX96874.1 - 2.1e-06 26.9 0.0 4.2e-06 25.9 0.0 1.5 1 0 0 1 1 1 1 Melibiase DUF3425 PF11905.8 KFX96875.1 - 1.5e-14 54.1 2.1 1.5e-14 54.0 0.6 1.7 1 1 1 2 2 2 1 Domain of unknown function (DUF3425) Tektin PF03148.14 KFX96875.1 - 0.026 13.3 0.5 0.044 12.5 0.5 1.3 1 0 0 1 1 1 0 Tektin family Metal_resist PF13801.6 KFX96875.1 - 0.06 13.5 0.1 0.13 12.4 0.1 1.5 1 0 0 1 1 1 0 Heavy-metal resistance Pyr_redox_3 PF13738.6 KFX96876.1 - 2.2e-09 37.0 0.4 9.4e-05 21.8 0.5 3.6 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 KFX96876.1 - 2.3e-08 32.9 0.0 2.3e-06 26.3 0.0 2.3 2 1 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 KFX96876.1 - 8.4e-08 31.8 0.0 5.3e-06 25.9 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KFX96876.1 - 1.5e-06 28.4 0.1 2.6e-05 24.4 0.1 2.7 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Shikimate_DH PF01488.20 KFX96876.1 - 0.00023 21.2 0.1 0.0022 18.1 0.0 2.3 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase NAD_binding_9 PF13454.6 KFX96876.1 - 0.0018 18.2 0.0 0.45 10.5 0.0 3.3 3 0 0 3 3 3 1 FAD-NAD(P)-binding DAO PF01266.24 KFX96876.1 - 0.0087 15.7 0.9 1.7 8.2 0.1 2.8 3 1 0 3 3 3 2 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 KFX96876.1 - 0.016 14.5 0.3 1.1 8.5 0.4 2.2 2 0 0 2 2 2 0 FAD binding domain FAD_binding_2 PF00890.24 KFX96876.1 - 0.038 13.1 0.0 0.064 12.3 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain 2-Hacid_dh_C PF02826.19 KFX96876.1 - 0.15 11.4 0.0 0.36 10.2 0.0 1.6 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ThiF PF00899.21 KFX96876.1 - 0.34 10.2 1.2 35 3.6 0.0 3.0 3 0 0 3 3 3 0 ThiF family Beta-lactamase PF00144.24 KFX96877.1 - 7.5e-64 216.0 0.0 8.5e-64 215.9 0.0 1.0 1 0 0 1 1 1 1 Beta-lactamase PBP PF01161.20 KFX96878.1 - 8e-13 48.9 0.1 1e-12 48.5 0.1 1.1 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein Citrate_synt PF00285.21 KFX96880.1 - 1.1e-101 340.5 0.0 1.5e-101 340.1 0.0 1.1 1 0 0 1 1 1 1 Citrate synthase, C-terminal domain FRB_dom PF08771.11 KFX96880.1 - 0.15 12.4 0.0 0.78 10.2 0.0 2.0 2 0 0 2 2 2 0 FKBP12-rapamycin binding domain RRM_1 PF00076.22 KFX96881.1 - 1.7e-08 34.1 0.0 3e-08 33.4 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CTD_bind PF04818.13 KFX96881.1 - 1.3e-07 32.3 0.0 2.6e-07 31.3 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase II-binding domain. Acyl-CoA_dh_1 PF00441.24 KFX96884.1 - 1.2e-40 139.2 3.3 1.9e-40 138.5 3.3 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 KFX96884.1 - 3.6e-29 101.7 0.6 7.5e-29 100.7 0.0 1.8 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 KFX96884.1 - 6.5e-24 84.0 0.1 1.5e-23 82.8 0.1 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 KFX96884.1 - 2.1e-17 63.6 0.4 3.2e-17 63.0 0.4 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain HpaB_N PF11794.8 KFX96884.1 - 0.024 14.3 0.0 0.066 12.9 0.0 1.7 1 1 0 1 1 1 0 4-hydroxyphenylacetate 3-hydroxylase N terminal Pkinase PF00069.25 KFX96885.1 - 2.8e-60 203.9 0.0 5.6e-60 202.9 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFX96885.1 - 2.3e-36 125.4 0.0 4.1e-36 124.6 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase HR1 PF02185.16 KFX96885.1 - 4.5e-23 81.1 18.7 2.7e-11 43.4 3.7 2.5 2 0 0 2 2 2 2 Hr1 repeat C1_1 PF00130.22 KFX96885.1 - 2.4e-19 69.0 29.1 7.2e-12 45.0 9.5 2.3 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) Pkinase_C PF00433.24 KFX96885.1 - 2e-14 54.0 2.3 5.8e-14 52.5 2.3 1.9 1 0 0 1 1 1 1 Protein kinase C terminal domain C2 PF00168.30 KFX96885.1 - 7.6e-05 22.9 0.1 0.00014 22.1 0.1 1.4 1 0 0 1 1 1 1 C2 domain Kinase-like PF14531.6 KFX96885.1 - 0.0046 16.3 0.0 0.0074 15.6 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 KFX96885.1 - 0.065 12.2 0.0 0.12 11.2 0.0 1.4 1 0 0 1 1 1 0 Haspin like kinase domain zf-RING_9 PF13901.6 KFX96885.1 - 5.1 7.0 20.8 3 7.8 5.6 2.4 2 0 0 2 2 2 0 Putative zinc-RING and/or ribbon She9_MDM33 PF05546.11 KFX96887.1 - 7.4e-81 270.7 2.2 1e-80 270.2 2.2 1.2 1 0 0 1 1 1 1 She9 / Mdm33 family PsbH PF00737.20 KFX96887.1 - 0.09 12.5 1.2 0.16 11.7 1.2 1.3 1 0 0 1 1 1 0 Photosystem II 10 kDa phosphoprotein ZapB PF06005.12 KFX96887.1 - 4 8.0 9.3 0.25 11.8 0.8 2.8 3 0 0 3 3 3 0 Cell division protein ZapB AA_permease PF00324.21 KFX96895.1 - 1.5e-139 465.7 48.7 1.9e-139 465.4 48.7 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KFX96895.1 - 5.8e-33 114.4 53.6 7.1e-33 114.1 53.6 1.1 1 0 0 1 1 1 1 Amino acid permease PALP PF00291.25 KFX96898.1 - 1.9e-10 40.7 0.0 2.5e-10 40.3 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Ribosomal_L7Ae PF01248.26 KFX96903.1 - 1.7e-20 72.6 1.0 4e-20 71.3 1.0 1.6 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family NPR2 PF06218.11 KFX96915.1 - 9.3e-122 406.9 5.0 6.2e-108 361.4 2.7 2.7 1 1 1 2 2 2 2 Nitrogen permease regulator 2 NPR3 PF03666.13 KFX96915.1 - 0.13 11.1 0.0 0.43 9.3 0.0 1.8 3 0 0 3 3 3 0 Nitrogen Permease regulator of amino acid transport activity 3 Methyltransf_16 PF10294.9 KFX96916.1 - 3.1e-17 62.9 0.0 4.7e-17 62.3 0.0 1.3 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_23 PF13489.6 KFX96916.1 - 1.3e-05 25.1 0.0 2.3e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KFX96916.1 - 0.00068 20.3 0.0 0.0018 18.9 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain PrmA PF06325.13 KFX96916.1 - 0.0027 17.1 0.0 0.0049 16.3 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 KFX96916.1 - 0.016 14.7 0.0 0.028 14.0 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain WD40 PF00400.32 KFX96919.1 - 6.5e-30 102.7 6.8 5.7e-05 23.8 0.0 7.1 7 0 0 7 7 7 5 WD domain, G-beta repeat F-box-like PF12937.7 KFX96919.1 - 3.7e-05 23.5 0.2 8.5e-05 22.4 0.2 1.7 1 0 0 1 1 1 1 F-box-like ANAPC4_WD40 PF12894.7 KFX96919.1 - 0.00012 22.4 0.2 0.83 10.0 0.0 4.1 3 1 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain F-box PF00646.33 KFX96919.1 - 0.00024 20.9 0.1 0.00058 19.7 0.1 1.6 1 0 0 1 1 1 1 F-box domain Nup160 PF11715.8 KFX96919.1 - 0.0025 16.5 0.0 0.14 10.7 0.0 2.9 3 0 0 3 3 3 1 Nucleoporin Nup120/160 F-box_4 PF15966.5 KFX96919.1 - 0.014 15.3 0.0 0.04 13.8 0.0 1.8 1 0 0 1 1 1 0 F-box Nucleoporin_N PF08801.11 KFX96919.1 - 0.22 10.2 0.0 0.75 8.5 0.0 1.7 2 0 0 2 2 2 0 Nup133 N terminal like TFIIA PF03153.13 KFX96919.1 - 0.34 10.8 20.7 0.64 10.0 20.7 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Med3 PF11593.8 KFX96919.1 - 2.8 7.0 27.7 4.1 6.5 27.7 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Peptidase_C12 PF01088.21 KFX96929.1 - 2.1e-66 223.7 0.0 2.7e-66 223.3 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 UCH_C PF18031.1 KFX96929.1 - 2.8e-09 36.7 0.0 6.3e-09 35.6 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolases Zn_clus PF00172.18 KFX96930.1 - 1.4e-09 38.0 10.2 2e-09 37.4 10.2 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 KFX96930.1 - 9.3e-06 24.7 0.1 1.5e-05 24.0 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Sugar_tr PF00083.24 KFX96936.1 - 9.7e-94 314.8 26.5 2.5e-63 214.5 5.3 2.0 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 KFX96936.1 - 3e-25 88.9 29.2 4e-22 78.6 11.4 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 KFX96936.1 - 0.00019 20.0 1.7 0.00033 19.2 1.7 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) TPR_19 PF14559.6 KFX96936.1 - 0.17 12.4 0.0 0.31 11.6 0.0 1.4 1 0 0 1 1 1 0 Tetratricopeptide repeat DUF4386 PF14329.6 KFX96939.1 - 0.12 12.2 5.2 0.15 11.9 5.2 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4386) PUF PF00806.19 KFX96944.1 - 4e-28 95.5 7.6 1.8e-08 33.6 0.1 4.8 5 0 0 5 5 5 4 Pumilio-family RNA binding repeat MFS_1 PF07690.16 KFX96947.1 - 8.7e-31 107.1 29.6 4.4e-30 104.8 30.6 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily Aminotran_3 PF00202.21 KFX96948.1 - 9.2e-119 396.7 0.0 1.1e-118 396.5 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.21 KFX96948.1 - 0.00027 20.2 0.0 0.00037 19.8 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 KFX96948.1 - 0.00084 18.7 0.0 0.0021 17.4 0.0 1.6 1 1 0 1 1 1 1 Beta-eliminating lyase OAM_dimer PF16554.5 KFX96948.1 - 0.037 14.5 0.0 0.09 13.2 0.0 1.6 1 0 0 1 1 1 0 Dimerisation domain of d-ornithine 4,5-aminomutase Glyco_transf_22 PF03901.17 KFX96949.1 - 1.2e-80 271.8 20.1 1.6e-80 271.4 20.1 1.0 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family Erf4 PF10256.9 KFX96950.1 - 0.022 14.9 0.0 0.055 13.6 0.0 1.5 1 1 0 1 1 1 0 Golgin subfamily A member 7/ERF4 family RR_TM4-6 PF06459.12 KFX96950.1 - 0.16 11.8 8.6 0.22 11.3 8.6 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 HA2 PF04408.23 KFX96950.1 - 2.2 8.6 5.0 4.8 7.5 5.0 1.5 1 0 0 1 1 1 0 Helicase associated domain (HA2) NARP1 PF12569.8 KFX96950.1 - 4.5 6.1 13.8 6.4 5.6 13.8 1.2 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 CDC45 PF02724.14 KFX96950.1 - 9.7 4.3 12.8 13 3.9 12.8 1.1 1 0 0 1 1 1 0 CDC45-like protein Transp_cyt_pur PF02133.15 KFX96952.1 - 6.2e-147 489.9 34.7 7.4e-147 489.7 34.7 1.1 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin DUF3405 PF11885.8 KFX96953.1 - 3.1e-149 497.9 0.0 3.8e-149 497.6 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3405) tRNA-synt_1d PF00750.19 KFX96958.1 - 6.9e-102 340.9 5.9 9.5e-102 340.5 5.9 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (R) DALR_1 PF05746.15 KFX96958.1 - 1.7e-30 105.6 0.1 5.3e-30 104.0 0.1 1.9 1 0 0 1 1 1 1 DALR anticodon binding domain Arg_tRNA_synt_N PF03485.16 KFX96958.1 - 2.1e-07 31.4 0.0 5.7e-07 30.0 0.0 1.8 1 0 0 1 1 1 1 Arginyl tRNA synthetase N terminal domain POT1 PF02765.17 KFX96958.1 - 0.12 12.2 0.0 0.44 10.4 0.0 1.9 2 0 0 2 2 2 0 Telomeric single stranded DNA binding POT1/CDC13 Hemerythrin PF01814.23 KFX96959.1 - 1.2e-06 29.1 0.0 2.6e-06 28.1 0.0 1.5 1 1 0 1 1 1 1 Hemerythrin HHE cation binding domain Glyco_hydro_61 PF03443.14 KFX96960.1 - 3.2e-48 164.4 0.0 3.7e-48 164.2 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 F5_F8_type_C PF00754.25 KFX96961.1 - 6.5e-11 42.4 0.0 1.6e-10 41.2 0.0 1.7 1 0 0 1 1 1 1 F5/8 type C domain Glyco_hydro_42 PF02449.15 KFX96961.1 - 0.015 14.7 0.0 0.56 9.5 0.0 2.1 1 1 1 2 2 2 0 Beta-galactosidase Sugar_tr PF00083.24 KFX96962.1 - 4.2e-81 273.1 23.5 4.8e-81 272.9 23.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KFX96962.1 - 1.6e-40 139.2 46.3 7.7e-35 120.5 23.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 KFX96962.1 - 0.0037 16.2 12.0 0.011 14.6 3.2 2.3 1 1 2 3 3 3 3 MFS_1 like family TRI12 PF06609.13 KFX96962.1 - 0.037 12.5 11.4 0.0059 15.1 4.4 2.5 2 1 1 3 3 3 0 Fungal trichothecene efflux pump (TRI12) DUF4231 PF14015.6 KFX96962.1 - 7.2 7.1 5.8 8.5 6.9 0.0 3.6 3 1 1 4 4 4 0 Protein of unknown function (DUF4231) Alpha-amylase PF00128.24 KFX96963.1 - 3.6e-114 381.8 0.1 7.7e-114 380.7 0.1 1.5 1 0 0 1 1 1 1 Alpha amylase, catalytic domain Malt_amylase_C PF16657.5 KFX96963.1 - 3.6e-09 36.6 0.0 9.4e-09 35.3 0.0 1.8 2 0 0 2 2 2 1 Maltogenic Amylase, C-terminal domain hDGE_amylase PF14701.6 KFX96963.1 - 0.0022 17.1 0.0 0.0036 16.5 0.0 1.2 1 0 0 1 1 1 1 Glycogen debranching enzyme, glucanotransferase domain Alpha-amylase_C PF02806.18 KFX96963.1 - 0.021 15.3 0.1 0.19 12.2 0.0 2.5 2 0 0 2 2 2 0 Alpha amylase, C-terminal all-beta domain DUF4202 PF13875.6 KFX96964.1 - 5.1e-77 258.0 1.7 5.7e-77 257.8 1.7 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4202) DUF5584 PF17822.1 KFX96964.1 - 0.013 14.9 0.0 0.019 14.4 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5584) Glyco_transf_10 PF00852.19 KFX96964.1 - 0.067 12.9 0.1 0.12 12.1 0.1 1.4 1 0 0 1 1 1 0 Glycosyltransferase family 10 (fucosyltransferase) C-term Kinesin_assoc PF16183.5 KFX96964.1 - 0.07 13.3 0.2 0.085 13.0 0.2 1.2 1 0 0 1 1 1 0 Kinesin-associated Glyco_hydro_31 PF01055.26 KFX96965.1 - 9.9e-112 374.3 1.6 1.4e-111 373.8 1.6 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 DUF4968 PF16338.5 KFX96965.1 - 1e-06 29.0 0.0 1.6e-06 28.3 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4968) Gal_mutarotas_2 PF13802.6 KFX96965.1 - 0.00018 21.7 0.9 0.0013 19.0 0.2 2.7 2 1 0 2 2 2 1 Galactose mutarotase-like Peptidase_M20 PF01546.28 KFX96966.1 - 1.5e-23 83.6 0.0 2.3e-23 83.0 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 KFX96966.1 - 6.6e-15 55.0 0.0 1.9e-14 53.5 0.0 1.8 1 0 0 1 1 1 1 Peptidase dimerisation domain SIMPL PF04402.14 KFX96966.1 - 0.067 13.6 0.0 0.1 13.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF541) Ldh_1_N PF00056.23 KFX96967.1 - 7.9e-45 152.4 0.1 2.1e-44 151.0 0.1 1.7 2 0 0 2 2 2 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.18 KFX96967.1 - 2.2e-44 151.4 0.1 6e-44 149.9 0.3 1.6 2 0 0 2 2 2 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain 3Beta_HSD PF01073.19 KFX96967.1 - 0.0073 15.3 0.0 0.01 14.8 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Sugar_tr PF00083.24 KFX96968.1 - 1.8e-37 129.3 23.6 2e-36 125.8 23.6 2.1 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KFX96968.1 - 2.4e-29 102.4 29.4 9.9e-23 80.6 13.1 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily PLDc PF00614.22 KFX96970.1 - 2.2e-15 56.1 2.2 1.6e-07 31.2 0.1 2.6 2 0 0 2 2 2 2 Phospholipase D Active site motif PLDc_2 PF13091.6 KFX96970.1 - 4.6e-15 55.7 0.0 2e-05 24.5 0.0 3.6 3 1 0 3 3 3 3 PLD-like domain GLTP PF08718.11 KFX96971.1 - 2e-46 158.0 0.0 2.5e-46 157.7 0.0 1.1 1 0 0 1 1 1 1 Glycolipid transfer protein (GLTP) Macro PF01661.21 KFX96972.1 - 8.7e-40 135.4 0.3 1.7e-39 134.5 0.3 1.5 1 0 0 1 1 1 1 Macro domain tRNA-synt_1c PF00749.21 KFX96973.1 - 5.4e-98 327.7 0.0 7.1e-98 327.4 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.18 KFX96973.1 - 4.9e-29 101.4 0.0 1.7e-28 99.7 0.0 1.9 2 0 0 2 2 2 1 tRNA synthetases class I (E and Q), anti-codon binding domain DUF3597 PF12200.8 KFX96973.1 - 0.04 14.4 1.2 0.078 13.5 1.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3597) Ribosomal_60s PF00428.19 KFX96973.1 - 5.1 7.8 12.9 12 6.6 12.9 1.6 1 0 0 1 1 1 0 60s Acidic ribosomal protein DUF2052 PF09747.9 KFX96975.1 - 0.0014 18.8 5.6 0.026 14.7 1.1 2.3 2 0 0 2 2 2 2 Coiled-coil domain containing protein (DUF2052) Nop14 PF04147.12 KFX96975.1 - 0.16 10.2 3.2 0.28 9.4 3.2 1.3 1 0 0 1 1 1 0 Nop14-like family PI3K_1B_p101 PF10486.9 KFX96975.1 - 0.17 9.6 0.7 0.26 9.0 0.7 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit RR_TM4-6 PF06459.12 KFX96975.1 - 0.29 10.9 2.3 5.2 6.8 0.6 2.1 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 DNA_pol_phi PF04931.13 KFX96975.1 - 0.85 7.6 8.9 1.3 7.0 8.9 1.2 1 0 0 1 1 1 0 DNA polymerase phi FAM176 PF14851.6 KFX96975.1 - 2.7 7.6 9.1 0.19 11.4 1.4 2.2 2 0 0 2 2 2 0 FAM176 family RXT2_N PF08595.11 KFX96975.1 - 6.6 6.7 6.9 0.62 10.1 0.7 2.0 2 0 0 2 2 2 0 RXT2-like, N-terminal PAXIP1_C PF15364.6 KFX96975.1 - 7.8 6.8 13.3 0.28 11.5 3.6 2.6 2 0 0 2 2 2 0 PAXIP1-associated-protein-1 C term PTIP binding protein Hydrophobin_2 PF06766.11 KFX96976.1 - 0.00022 21.1 6.3 0.00046 20.1 6.3 1.6 1 1 0 1 1 1 1 Fungal hydrophobin Hydrophobin_2 PF06766.11 KFX96977.1 - 1.8e-07 31.0 5.3 2.9e-07 30.3 5.3 1.5 1 1 0 1 1 1 1 Fungal hydrophobin Methyltransf_2 PF00891.18 KFX96978.1 - 5.2e-22 78.2 0.0 8.8e-22 77.4 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase domain CheR PF01739.18 KFX96978.1 - 0.07 12.6 0.0 0.16 11.4 0.0 1.5 1 0 0 1 1 1 0 CheR methyltransferase, SAM binding domain CcmD PF04995.14 KFX96978.1 - 0.096 12.8 0.1 0.19 11.9 0.1 1.4 1 0 0 1 1 1 0 Heme exporter protein D (CcmD) F-box-like PF12937.7 KFX96978.1 - 0.11 12.4 0.0 0.26 11.2 0.0 1.7 1 0 0 1 1 1 0 F-box-like HTH_AsnC-type PF13404.6 KFX96978.1 - 0.16 11.8 0.0 0.43 10.4 0.0 1.7 1 0 0 1 1 1 0 AsnC-type helix-turn-helix domain PIP5K PF01504.18 KFX96981.1 - 2.3e-34 118.9 1.9 1.1e-25 90.4 0.1 3.0 2 1 1 3 3 3 2 Phosphatidylinositol-4-phosphate 5-Kinase Metallophos PF00149.28 KFX96982.1 - 1.4e-35 123.7 0.1 2.2e-35 123.0 0.1 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 KFX96982.1 - 6e-16 58.6 0.0 1.3e-15 57.5 0.0 1.6 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain SUR7 PF06687.12 KFX96983.1 - 5.5e-27 94.8 11.2 7.4e-27 94.4 11.2 1.2 1 0 0 1 1 1 1 SUR7/PalI family SET PF00856.28 KFX96984.1 - 4.6e-14 53.2 0.1 4.6e-14 53.2 0.1 2.5 2 2 0 2 2 2 1 SET domain Ezh2_MCSS PF18600.1 KFX96984.1 - 0.00065 19.3 0.4 0.0015 18.1 0.4 1.6 1 0 0 1 1 1 1 MCSS domain SLT_2 PF13406.6 KFX96984.1 - 0.1 11.8 0.0 0.21 10.8 0.0 1.4 1 0 0 1 1 1 0 Transglycosylase SLT domain RPEL PF02755.15 KFX96985.1 - 1e-25 88.6 18.8 1e-09 37.7 3.6 4.0 4 0 0 4 4 4 3 RPEL repeat IMS PF00817.20 KFX96986.1 - 5.1e-41 140.2 0.1 1.3e-40 138.8 0.0 1.7 2 0 0 2 2 2 1 impB/mucB/samB family IMS_C PF11799.8 KFX96986.1 - 2e-10 41.4 0.0 4.7e-10 40.2 0.0 1.6 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.8 KFX96986.1 - 0.0038 17.5 0.0 0.011 16.0 0.0 1.9 1 0 0 1 1 1 1 IMS family HHH motif PHD20L1_u1 PF16660.5 KFX96986.1 - 0.13 13.0 9.8 0.57 11.0 4.2 2.6 2 0 0 2 2 2 0 PHD finger protein 20-like protein 1 FKBP_C PF00254.28 KFX96987.1 - 7.8e-34 115.9 0.0 1.2e-33 115.3 0.0 1.3 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase Inhibitor_I53 PF11714.8 KFX96987.1 - 0.1 12.8 0.6 0.82 9.9 0.0 2.1 2 0 0 2 2 2 0 Thrombin inhibitor Madanin Ric8 PF10165.9 KFX96990.1 - 2.2e-63 214.9 0.1 2.4e-63 214.8 0.1 1.0 1 0 0 1 1 1 1 Guanine nucleotide exchange factor synembryn SPRY PF00622.28 KFX96992.1 - 8.5e-28 96.9 0.2 1.5e-27 96.1 0.2 1.4 1 0 0 1 1 1 1 SPRY domain CLTH PF10607.9 KFX96992.1 - 8.8e-26 90.6 0.0 1.2e-25 90.1 0.0 1.2 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain LisH PF08513.11 KFX96992.1 - 0.0001 22.1 1.9 0.00014 21.7 0.0 2.3 3 0 0 3 3 3 1 LisH CG-1 PF03859.16 KFX96992.1 - 0.043 13.6 0.0 0.11 12.2 0.0 1.7 1 0 0 1 1 1 0 CG-1 domain FOG_N PF15888.5 KFX96992.1 - 1.1 9.6 3.2 65 3.9 1.7 3.2 2 1 1 3 3 3 0 Folded gastrulation N-terminus NACHT PF05729.12 KFX96995.1 - 9.9e-07 28.8 0.1 2.9e-06 27.3 0.0 1.8 2 0 0 2 2 2 1 NACHT domain SesA PF17107.5 KFX96995.1 - 1.4e-05 25.3 0.1 3.6e-05 23.9 0.1 1.7 1 0 0 1 1 1 1 N-terminal domain on NACHT_NTPase and P-loop NTPases AAA_22 PF13401.6 KFX96995.1 - 9.7e-05 22.7 0.2 0.00076 19.8 0.0 2.2 2 1 0 2 2 2 1 AAA domain HMG_box PF00505.19 KFX97002.1 - 1.8e-11 44.3 0.1 4.6e-11 43.0 0.1 1.8 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KFX97002.1 - 0.016 15.7 0.1 0.039 14.5 0.1 1.6 1 0 0 1 1 1 0 HMG-box domain MATalpha_HMGbox PF04769.12 KFX97002.1 - 0.094 12.0 0.0 0.15 11.3 0.0 1.3 1 0 0 1 1 1 0 Mating-type protein MAT alpha 1 HMG-box Lactamase_B PF00753.27 KFX97006.1 - 0.024 14.7 0.3 0.055 13.5 0.3 1.5 1 1 0 1 1 1 0 Metallo-beta-lactamase superfamily Prok-RING_1 PF14446.6 KFX97006.1 - 0.22 11.5 0.7 0.42 10.6 0.2 1.6 1 1 0 1 1 1 0 Prokaryotic RING finger family 1 Amidase PF01425.21 KFX97007.1 - 1.9e-89 300.7 0.0 2.3e-89 300.5 0.0 1.1 1 0 0 1 1 1 1 Amidase NB-ARC PF00931.22 KFX97007.1 - 0.084 12.0 0.0 0.19 10.9 0.0 1.5 1 0 0 1 1 1 0 NB-ARC domain CASP_C PF08172.12 KFX97048.1 - 2.3e-90 302.3 0.2 2.3e-90 302.3 0.2 3.8 4 0 0 4 4 4 2 CASP C terminal Cep57_MT_bd PF06657.13 KFX97048.1 - 0.0019 18.6 23.3 0.012 16.1 2.1 4.8 5 0 0 5 5 5 2 Centrosome microtubule-binding domain of Cep57 UPF0184 PF03670.13 KFX97048.1 - 0.054 13.9 8.6 0.88 10.0 0.5 3.5 2 1 0 2 2 2 0 Uncharacterised protein family (UPF0184) ZapB PF06005.12 KFX97048.1 - 0.15 12.6 0.2 0.15 12.6 0.2 6.8 4 1 2 6 6 6 0 Cell division protein ZapB DUF4763 PF15960.5 KFX97048.1 - 0.18 11.1 0.1 0.18 11.1 0.1 4.3 5 0 0 5 5 5 0 Domain of unknown function (DUF4763) LPP PF04728.13 KFX97048.1 - 0.31 11.5 13.3 2.3 8.6 0.4 5.0 4 0 0 4 4 4 0 Lipoprotein leucine-zipper DUF1664 PF07889.12 KFX97048.1 - 1.5 8.9 24.5 3.7 7.6 0.4 5.4 4 1 1 5 5 5 0 Protein of unknown function (DUF1664) MscS_porin PF12795.7 KFX97048.1 - 8.2 5.9 57.4 1.1 8.7 10.9 5.3 4 1 1 5 5 5 0 Mechanosensitive ion channel porin domain VCBS PF13517.6 KFX97049.1 - 4.4e-36 123.3 59.2 2.1e-09 37.8 2.4 8.8 4 2 6 10 10 10 8 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella Lipase_GDSL_2 PF13472.6 KFX97049.1 - 3.1e-07 31.0 0.3 9e-07 29.5 0.3 1.8 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family FG-GAP PF01839.23 KFX97049.1 - 3.1e-07 30.4 28.1 0.0077 16.3 1.1 6.6 6 0 0 6 6 6 4 FG-GAP repeat Lipase_GDSL PF00657.22 KFX97049.1 - 4.7e-06 26.7 0.0 9.5e-06 25.7 0.0 1.5 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase TcdB_toxin_midN PF12256.8 KFX97049.1 - 7.9e-06 25.4 8.9 2.4 7.5 0.0 6.3 3 3 2 6 6 6 4 Insecticide toxin TcdB middle/N-terminal region G-alpha PF00503.20 KFX97050.1 - 6.4e-111 370.9 0.7 8.2e-111 370.6 0.7 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 KFX97050.1 - 6.8e-14 51.7 1.0 3.9e-09 36.2 0.1 2.5 2 1 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.12 KFX97050.1 - 6.6e-05 22.4 2.5 0.004 16.5 0.1 3.0 2 2 1 3 3 3 2 Gtr1/RagA G protein conserved region FtsK_SpoIIIE PF01580.18 KFX97050.1 - 0.004 16.5 0.0 0.016 14.6 0.0 1.8 2 0 0 2 2 2 1 FtsK/SpoIIIE family Roc PF08477.13 KFX97050.1 - 0.033 14.4 0.1 4.4 7.5 0.0 2.4 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_29 PF13555.6 KFX97050.1 - 0.11 12.3 0.1 0.34 10.7 0.0 1.8 2 0 0 2 2 2 0 P-loop containing region of AAA domain SUR7 PF06687.12 KFX97051.1 - 5.3e-16 58.9 8.1 9.1e-15 54.9 9.0 1.9 1 1 1 2 2 2 1 SUR7/PalI family COX2_TM PF02790.15 KFX97051.1 - 0.039 14.1 0.9 0.039 14.1 0.9 2.1 2 0 0 2 2 2 0 Cytochrome C oxidase subunit II, transmembrane domain TMEM51 PF15345.6 KFX97051.1 - 0.25 11.1 0.0 0.45 10.3 0.0 1.4 1 0 0 1 1 1 0 Transmembrane protein 51 DUF872 PF05915.12 KFX97051.1 - 0.27 11.4 2.0 0.93 9.7 0.1 2.3 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF872) EphA2_TM PF14575.6 KFX97051.1 - 0.27 12.1 0.7 11 7.0 0.0 2.9 3 0 0 3 3 3 0 Ephrin type-A receptor 2 transmembrane domain RCR PF12273.8 KFX97051.1 - 0.49 11.1 0.1 0.49 11.1 0.1 2.0 3 0 0 3 3 2 0 Chitin synthesis regulation, resistance to Congo red MRAP PF15183.6 KFX97051.1 - 0.52 10.3 0.1 0.52 10.3 0.1 3.0 2 1 1 3 3 3 0 Melanocortin-2 receptor accessory protein family DUF805 PF05656.14 KFX97051.1 - 1.6 9.2 6.0 0.43 11.0 1.8 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF805) ERGIC_N PF13850.6 KFX97051.1 - 2.7 8.4 4.2 3.7 8.0 0.0 2.6 2 1 1 3 3 3 0 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) DUF2663 PF10864.8 KFX97051.1 - 3 8.3 4.6 0.49 10.8 0.2 1.9 2 1 0 2 2 2 0 Protein of unknown function (DUF2663) zf-LITAF-like PF10601.9 KFX97051.1 - 4.1 7.7 0.0 4.1 7.7 0.0 3.0 3 1 0 3 3 3 0 LITAF-like zinc ribbon domain HhH-GPD PF00730.25 KFX97052.1 - 3e-10 40.5 0.0 8.4e-10 39.1 0.0 1.7 2 0 0 2 2 2 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.23 KFX97052.1 - 3.6e-08 32.9 0.0 3.6e-08 32.9 0.0 2.1 3 0 0 3 3 3 1 Helix-hairpin-helix motif HHH_8 PF14716.6 KFX97052.1 - 0.019 15.3 0.0 0.037 14.4 0.0 1.5 1 0 0 1 1 1 0 Helix-hairpin-helix domain Lectin_leg-like PF03388.13 KFX97065.1 - 9.7e-07 28.4 0.0 1.2e-06 28.1 0.0 1.1 1 0 0 1 1 1 1 Legume-like lectin family Alg6_Alg8 PF03155.15 KFX97066.1 - 2.4e-177 590.8 29.5 2.6e-176 587.3 29.5 1.9 1 1 0 1 1 1 1 ALG6, ALG8 glycosyltransferase family Pkinase PF00069.25 KFX97073.1 - 1.6e-10 40.8 0.0 2.3e-10 40.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFX97073.1 - 7.3e-06 25.4 0.0 1.2e-05 24.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase eIF3_subunit PF08597.10 KFX97076.1 - 0.16 11.8 7.1 0.18 11.7 7.1 1.1 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit YL1 PF05764.13 KFX97076.1 - 0.51 10.4 12.3 0.83 9.7 12.3 1.3 1 1 0 1 1 1 0 YL1 nuclear protein CDC45 PF02724.14 KFX97076.1 - 3.4 5.8 4.9 3.8 5.7 4.9 1.0 1 0 0 1 1 1 0 CDC45-like protein CTX_RstB PF07459.11 KFX97077.1 - 0.0091 16.2 0.0 0.015 15.6 0.0 1.3 1 0 0 1 1 1 1 CTX phage RstB protein CENP-N PF05238.13 KFX97079.1 - 9.2 5.5 10.5 0.89 8.8 5.5 1.7 1 1 0 1 1 1 0 Kinetochore protein CHL4 like HEAT_2 PF13646.6 KFX97098.1 - 1.2e-09 38.4 2.7 0.27 11.6 0.0 7.0 6 1 2 8 8 8 4 HEAT repeats HEAT PF02985.22 KFX97098.1 - 1.1e-06 28.4 22.6 0.87 10.0 0.0 11.4 12 0 0 12 12 12 2 HEAT repeat TAF6_C PF07571.13 KFX97098.1 - 0.0003 21.1 0.7 2.8 8.3 0.0 5.8 5 0 0 5 5 5 1 TAF6 C-terminal HEAT repeat domain CLASP_N PF12348.8 KFX97098.1 - 0.0004 20.0 0.4 0.72 9.4 0.0 3.7 3 0 0 3 3 3 2 CLASP N terminal Cnd1 PF12717.7 KFX97098.1 - 0.0024 17.9 0.2 2.2 8.3 0.0 4.7 4 1 2 6 6 6 1 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.7 KFX97098.1 - 0.0067 17.0 0.0 1.1 9.9 0.0 4.3 5 0 0 5 5 5 1 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.6 KFX97098.1 - 0.014 15.9 7.9 4.2 8.0 0.0 6.9 8 0 0 8 8 8 0 HEAT-like repeat NOG1_N PF17835.1 KFX97098.1 - 0.066 13.2 0.1 9.8 6.1 0.0 2.8 2 0 0 2 2 2 0 NOG1 N-terminal helical domain SARAF PF06682.12 KFX97099.1 - 0.11 12.1 0.0 0.16 11.6 0.0 1.2 1 0 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis DUF2207 PF09972.9 KFX97099.1 - 9.7 4.8 5.6 0.79 8.4 0.2 1.8 1 1 1 2 2 2 0 Predicted membrane protein (DUF2207) GFA PF04828.14 KFX97100.1 - 5.6e-11 42.6 0.3 0.00037 20.8 0.2 2.7 2 0 0 2 2 2 2 Glutathione-dependent formaldehyde-activating enzyme Methyltransf_23 PF13489.6 KFX97100.1 - 8.2e-07 29.0 0.0 1.4e-06 28.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KFX97100.1 - 2e-06 27.7 0.0 7.5e-06 25.8 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 KFX97100.1 - 2.2e-06 28.3 0.0 4.6e-06 27.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KFX97100.1 - 1.4e-05 25.7 0.0 7.5e-05 23.4 0.0 2.2 2 1 0 2 2 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KFX97100.1 - 0.00032 21.3 0.0 0.0012 19.4 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KFX97100.1 - 0.012 15.1 0.0 0.025 14.1 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain DUF1106 PF06523.11 KFX97100.1 - 0.086 12.9 0.0 0.22 11.6 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1106) zf-NADH-PPase PF09297.11 KFX97100.1 - 0.53 10.0 10.1 0.52 10.0 0.2 3.1 3 0 0 3 3 3 0 NADH pyrophosphatase zinc ribbon domain zinc_ribbon_2 PF13240.6 KFX97100.1 - 0.54 10.1 11.3 0.72 9.7 0.3 3.7 3 0 0 3 3 3 0 zinc-ribbon domain DZR PF12773.7 KFX97100.1 - 1.1 9.3 6.8 25 5.0 0.0 2.9 2 1 0 2 2 2 0 Double zinc ribbon MFS_1 PF07690.16 KFX97101.1 - 1.8e-35 122.5 38.3 8.9e-28 97.2 24.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 KFX97101.1 - 2e-05 23.6 0.7 2e-05 23.6 0.7 2.8 1 1 1 3 3 3 1 MFS_1 like family adh_short PF00106.25 KFX97102.1 - 3.7e-23 82.0 0.0 5e-23 81.6 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KFX97102.1 - 2.8e-17 63.1 0.0 3.7e-17 62.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KFX97102.1 - 2.2e-06 27.7 0.0 2.9e-06 27.3 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KFX97102.1 - 0.00018 21.1 0.0 0.0009 18.8 0.0 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KFX97102.1 - 0.04 13.3 0.0 0.087 12.2 0.0 1.6 1 1 0 1 1 1 0 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.6 KFX97102.1 - 0.13 12.2 0.0 0.17 11.8 0.0 1.3 1 1 0 1 1 1 0 NAD(P)H-binding DUF2642 PF10842.8 KFX97102.1 - 0.16 11.8 0.2 0.94 9.4 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2642) Fungal_trans PF04082.18 KFX97103.1 - 0.081 11.9 0.1 0.13 11.3 0.1 1.3 1 0 0 1 1 1 0 Fungal specific transcription factor domain TENA_THI-4 PF03070.16 KFX97104.1 - 0.00056 19.8 0.0 0.071 12.9 0.0 2.9 2 1 1 3 3 3 2 TENA/THI-4/PQQC family MARVEL PF01284.23 KFX97105.1 - 5.5e-22 78.4 19.2 6.8e-22 78.1 19.2 1.0 1 0 0 1 1 1 1 Membrane-associating domain Glyco_hydro_43 PF04616.14 KFX97107.1 - 7.1e-30 104.3 4.0 2.2e-18 66.6 0.7 2.7 2 1 0 2 2 2 2 Glycosyl hydrolases family 43 Methyltransf_25 PF13649.6 KFX97108.1 - 1.9e-19 70.2 0.0 3e-19 69.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KFX97108.1 - 1.4e-17 64.1 0.0 2.1e-17 63.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KFX97108.1 - 7.1e-13 48.6 0.0 9.3e-13 48.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KFX97108.1 - 7.4e-11 42.2 0.0 1.1e-10 41.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KFX97108.1 - 2e-08 34.9 0.0 3.4e-08 34.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KFX97108.1 - 2.3e-06 27.1 0.0 1e-05 25.0 0.0 1.8 1 1 1 2 2 2 1 ubiE/COQ5 methyltransferase family CMAS PF02353.20 KFX97108.1 - 2.8e-05 23.5 0.0 3.8e-05 23.1 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase MTS PF05175.14 KFX97108.1 - 8.4e-05 22.2 0.0 0.00013 21.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain NodS PF05401.11 KFX97108.1 - 0.00041 20.0 0.0 0.00053 19.7 0.0 1.2 1 0 0 1 1 1 1 Nodulation protein S (NodS) Methyltransf_16 PF10294.9 KFX97108.1 - 0.0044 16.8 0.0 0.0063 16.3 0.0 1.3 1 0 0 1 1 1 1 Lysine methyltransferase tRNA_U5-meth_tr PF05958.11 KFX97108.1 - 0.0071 15.4 0.0 0.0093 15.0 0.0 1.1 1 0 0 1 1 1 1 tRNA (Uracil-5-)-methyltransferase Pox_MCEL PF03291.16 KFX97108.1 - 0.053 12.6 0.0 0.072 12.2 0.0 1.2 1 0 0 1 1 1 0 mRNA capping enzyme Methyltransf_18 PF12847.7 KFX97108.1 - 0.06 13.3 0.0 0.11 12.4 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain PrmA PF06325.13 KFX97108.1 - 0.11 11.9 0.0 0.15 11.5 0.0 1.1 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) ADH_N PF08240.12 KFX97109.1 - 1.4e-20 73.2 0.3 2.9e-20 72.2 0.3 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KFX97109.1 - 1.5e-09 37.9 0.0 1.5e-08 34.7 0.0 2.5 2 1 0 2 2 2 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 KFX97109.1 - 1.1e-06 28.2 0.0 1.7e-06 27.5 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 KFX97109.1 - 1.8e-05 24.1 0.4 2.7e-05 23.5 0.0 1.5 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain Shikimate_DH PF01488.20 KFX97109.1 - 0.012 15.7 0.0 0.019 15.0 0.0 1.2 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase NAD_binding_2 PF03446.15 KFX97109.1 - 0.016 15.4 0.0 0.026 14.7 0.0 1.4 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.17 KFX97109.1 - 0.028 15.0 0.0 0.11 13.0 0.0 1.9 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent 3HCDH_N PF02737.18 KFX97109.1 - 0.054 13.4 0.0 0.086 12.7 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pet100 PF09803.9 KFX97110.1 - 2.7e-18 66.3 1.1 2.7e-18 66.3 1.1 2.1 3 0 0 3 3 3 1 Pet100 ECH_1 PF00378.20 KFX97111.1 - 1.4e-18 67.1 0.0 1.7e-18 66.9 0.0 1.2 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KFX97111.1 - 3.1e-13 49.9 0.0 3.6e-13 49.7 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase cwf21 PF08312.12 KFX97112.1 - 5e-17 61.8 8.1 5e-17 61.8 8.1 2.1 2 0 0 2 2 2 1 cwf21 domain Cas_GSU0054 PF09609.10 KFX97112.1 - 0.031 13.0 0.1 0.04 12.6 0.1 1.1 1 0 0 1 1 1 0 CRISPR-associated protein, GSU0054 family (Cas_GSU0054) DUF1129 PF06570.11 KFX97112.1 - 0.054 13.0 0.3 0.075 12.5 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1129) DUF3684 PF12449.8 KFX97113.1 - 1.5e-50 172.0 0.1 2.1e-50 171.6 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3684) Reprolysin_4 PF13583.6 KFX97113.1 - 0.052 13.2 0.5 0.16 11.6 0.1 1.9 2 0 0 2 2 2 0 Metallo-peptidase family M12B Reprolysin-like F-box PF00646.33 KFX97115.1 - 0.0014 18.5 0.0 0.0031 17.4 0.0 1.6 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 KFX97115.1 - 0.026 14.4 0.1 0.062 13.2 0.1 1.6 1 0 0 1 1 1 0 F-box-like ABC_tran PF00005.27 KFX97116.1 - 2.6e-50 170.5 0.0 1.8e-28 99.8 0.0 2.4 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 KFX97116.1 - 2.1e-29 103.0 36.4 1.5e-22 80.6 20.8 2.4 2 0 0 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.19 KFX97116.1 - 3.8e-11 42.9 2.5 0.017 14.5 0.0 4.2 3 1 1 4 4 4 4 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 KFX97116.1 - 8.9e-08 32.3 4.3 0.083 12.7 0.1 4.2 2 2 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 KFX97116.1 - 1.8e-06 28.2 0.0 0.14 12.5 0.0 3.0 3 1 0 3 3 2 2 AAA domain RsgA_GTPase PF03193.16 KFX97116.1 - 3e-06 27.3 0.1 0.015 15.2 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase AAA_29 PF13555.6 KFX97116.1 - 9.2e-06 25.3 0.2 0.12 12.1 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.6 KFX97116.1 - 5.9e-05 23.5 0.1 0.35 11.2 0.0 2.7 2 0 0 2 2 2 2 AAA ATPase domain AAA_23 PF13476.6 KFX97116.1 - 6.1e-05 23.6 0.3 0.059 13.9 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_24 PF13479.6 KFX97116.1 - 0.00045 20.0 0.1 0.0065 16.2 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 KFX97116.1 - 0.00054 20.1 0.0 1.4 9.1 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA PF00004.29 KFX97116.1 - 0.00071 20.0 0.2 5.1 7.5 0.0 3.7 3 1 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 KFX97116.1 - 0.0012 19.3 0.0 0.32 11.5 0.0 2.5 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.23 KFX97116.1 - 0.0015 18.6 0.1 1.1 9.4 0.0 2.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_15 PF13175.6 KFX97116.1 - 0.0018 18.1 0.0 1.8 8.2 0.0 2.2 2 0 0 2 2 2 2 AAA ATPase domain AAA_30 PF13604.6 KFX97116.1 - 0.002 17.9 0.0 0.55 9.9 0.0 3.1 3 1 0 3 3 3 1 AAA domain AAA_7 PF12775.7 KFX97116.1 - 0.0029 17.1 0.0 1.5 8.3 0.0 2.5 2 0 0 2 2 2 1 P-loop containing dynein motor region RNA_helicase PF00910.22 KFX97116.1 - 0.0063 16.9 0.0 5.9 7.3 0.0 2.7 2 0 0 2 2 2 0 RNA helicase Adeno_IVa2 PF02456.15 KFX97116.1 - 0.012 14.4 1.0 0.14 10.9 0.1 2.4 2 0 0 2 2 2 0 Adenovirus IVa2 protein Dynamin_N PF00350.23 KFX97116.1 - 0.014 15.4 0.2 2.7 8.0 0.0 2.4 2 0 0 2 2 2 0 Dynamin family Rad17 PF03215.15 KFX97116.1 - 0.018 15.0 0.0 3.7 7.4 0.0 2.5 2 0 0 2 2 2 0 Rad17 P-loop domain ATPase_2 PF01637.18 KFX97116.1 - 0.019 14.9 0.0 0.19 11.6 0.0 2.2 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea AAA_25 PF13481.6 KFX97116.1 - 0.021 14.4 0.0 14 5.2 0.0 3.3 3 0 0 3 3 3 0 AAA domain AAA_5 PF07728.14 KFX97116.1 - 0.022 14.8 0.2 9.8 6.2 0.0 2.9 3 0 0 3 3 2 0 AAA domain (dynein-related subfamily) cobW PF02492.19 KFX97116.1 - 0.071 12.7 0.3 2 7.9 0.0 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain PRK PF00485.18 KFX97116.1 - 0.075 12.8 0.1 0.22 11.3 0.0 1.8 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family Roc PF08477.13 KFX97116.1 - 0.087 13.0 0.0 26 5.1 0.0 2.9 3 0 0 3 3 2 0 Ras of Complex, Roc, domain of DAPkinase NACHT PF05729.12 KFX97116.1 - 0.11 12.4 0.1 3.8 7.4 0.0 2.6 2 0 0 2 2 2 0 NACHT domain DUF815 PF05673.13 KFX97116.1 - 0.16 11.1 0.0 3 6.9 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_11 PF13086.6 KFX97116.1 - 0.16 11.7 0.1 22 4.7 0.0 2.8 2 1 0 2 2 2 0 AAA domain ATP-synt_ab PF00006.25 KFX97116.1 - 0.18 11.4 0.1 5.9 6.5 0.0 2.5 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain DUF3290 PF11694.8 KFX97116.1 - 0.44 10.5 2.6 0.49 10.4 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3290) DUF1481 PF07356.12 KFX97120.1 - 0.2 11.4 0.0 0.34 10.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1481) TAF PF02969.17 KFX97121.1 - 0.15 12.3 0.0 0.26 11.5 0.0 1.4 1 0 0 1 1 1 0 TATA box binding protein associated factor (TAF) EXS PF03124.14 KFX97122.1 - 2.7e-109 365.5 12.6 3e-109 365.3 12.6 1.0 1 0 0 1 1 1 1 EXS family Pex2_Pex12 PF04757.14 KFX97123.1 - 2.6e-43 148.2 5.5 3.3e-43 147.9 5.5 1.1 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4_2 PF13923.6 KFX97123.1 - 2.7e-11 43.1 8.3 4.3e-11 42.5 8.3 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KFX97123.1 - 6.5e-11 42.4 9.0 1.1e-10 41.6 9.0 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 KFX97123.1 - 9.3e-10 38.2 6.4 1.5e-09 37.5 6.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KFX97123.1 - 1.3e-08 34.5 8.8 2e-08 33.9 8.8 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KFX97123.1 - 5.7e-07 29.5 7.9 1.2e-06 28.5 7.9 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 KFX97123.1 - 6.4e-07 29.2 5.2 1.1e-06 28.5 5.2 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 KFX97123.1 - 2.2e-06 27.7 7.5 3.9e-06 26.9 7.5 1.4 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.7 KFX97123.1 - 4.8e-06 26.8 8.9 8.6e-06 25.9 8.5 1.6 1 1 0 1 1 1 1 RING-H2 zinc finger domain Prok-RING_4 PF14447.6 KFX97123.1 - 5e-05 23.1 9.5 8.2e-05 22.4 9.5 1.3 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_10 PF16685.5 KFX97123.1 - 0.0025 17.9 8.2 0.0043 17.1 8.2 1.3 1 0 0 1 1 1 1 zinc RING finger of MSL2 zf-Nse PF11789.8 KFX97123.1 - 0.013 15.3 1.1 0.023 14.5 1.1 1.4 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-RING_6 PF14835.6 KFX97123.1 - 0.017 15.0 4.8 0.036 13.9 4.8 1.5 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-RING_4 PF14570.6 KFX97123.1 - 0.093 12.5 6.5 0.21 11.4 6.5 1.6 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING_11 PF17123.5 KFX97123.1 - 0.77 9.6 3.3 1.9 8.3 3.3 1.7 1 0 0 1 1 1 0 RING-like zinc finger Imm17 PF15562.6 KFX97123.1 - 0.94 9.4 3.0 0.45 10.4 0.2 1.9 2 0 0 2 2 2 0 Immunity protein 17 zf-LYAR PF08790.11 KFX97124.1 - 5.4e-15 55.0 1.4 5.4e-15 55.0 1.4 2.5 2 0 0 2 2 2 1 LYAR-type C2HC zinc finger zf-ACC PF17848.1 KFX97124.1 - 0.19 11.8 0.4 0.37 10.9 0.4 1.5 1 0 0 1 1 1 0 Acetyl-coA carboxylase zinc finger domain zf-TRAF PF02176.18 KFX97124.1 - 1.3 9.8 5.0 0.16 12.7 0.8 1.7 2 0 0 2 2 2 0 TRAF-type zinc finger DUF1117 PF06547.12 KFX97124.1 - 5.5 7.6 10.1 0.13 12.8 2.9 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1117) Sugar_tr PF00083.24 KFX97126.1 - 1.8e-128 429.2 24.7 2.1e-128 429.0 24.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KFX97126.1 - 3e-22 79.1 59.9 1.9e-21 76.4 33.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Metallophos PF00149.28 KFX97127.1 - 3.1e-10 40.9 0.1 7.1e-10 39.7 0.1 1.7 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Glyco_hydro_3_C PF01915.22 KFX97128.1 - 4.5e-65 219.4 0.0 1.5e-64 217.7 0.0 1.9 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 KFX97128.1 - 1.5e-53 182.2 0.0 3.5e-53 181.1 0.0 1.6 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 KFX97128.1 - 6e-22 77.5 1.8 2.6e-21 75.5 0.3 2.8 3 0 0 3 3 3 1 Fibronectin type III-like domain PA14 PF07691.12 KFX97128.1 - 3.8e-18 65.7 0.0 7.2e-18 64.8 0.0 1.4 1 0 0 1 1 1 1 PA14 domain DUF202 PF02656.15 KFX97130.1 - 3.9e-16 59.3 0.3 3.9e-16 59.3 0.3 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF202) DUF4131 PF13567.6 KFX97130.1 - 0.037 13.7 1.6 0.084 12.5 1.6 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) DUF5527 PF17665.1 KFX97132.1 - 0.11 12.0 0.1 0.27 10.7 0.1 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF5527) CbeA_antitoxin PF06154.11 KFX97143.1 - 0.079 13.5 0.0 0.24 12.0 0.1 1.7 2 0 0 2 2 2 0 CbeA_antitoxin, type IV, cytoskeleton bundling-enhancing factor A MFS_1 PF07690.16 KFX97144.1 - 5.3e-44 150.6 55.6 1.3e-43 149.3 54.7 2.3 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KFX97144.1 - 1.4e-11 43.9 9.7 1.4e-11 43.9 9.7 2.4 3 0 0 3 3 3 1 Sugar (and other) transporter HMA PF00403.26 KFX97145.1 - 2.5e-13 50.2 0.0 5.7e-13 49.1 0.0 1.6 1 0 0 1 1 1 1 Heavy-metal-associated domain Sod_Cu PF00080.20 KFX97145.1 - 1.3e-10 41.6 0.0 2.1e-10 40.9 0.0 1.3 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) zinc_ribbon_16 PF17034.5 KFX97146.1 - 1.4e-11 44.7 6.3 3.6e-11 43.4 6.3 1.7 1 0 0 1 1 1 1 Zinc-ribbon like family ANAPC4_WD40 PF12894.7 KFX97146.1 - 0.0004 20.6 0.0 13 6.1 0.0 3.6 2 1 1 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain Zn_ribbon_17 PF17120.5 KFX97146.1 - 0.00089 18.8 7.8 0.003 17.1 7.8 1.9 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-RING_2 PF13639.6 KFX97146.1 - 5.1 7.5 8.6 0.74 10.2 4.0 2.0 2 0 0 2 2 2 0 Ring finger domain Efg1 PF10153.9 KFX97147.1 - 2.1e-38 131.2 9.7 2.1e-38 131.2 9.7 2.0 2 1 0 2 2 2 1 rRNA-processing protein Efg1 SH3-RhoG_link PF16609.5 KFX97147.1 - 0.48 10.1 6.5 0.12 12.1 2.2 2.1 1 1 1 2 2 2 0 SH3-RhoGEF linking unstructured region Mrpl_C PF18502.1 KFX97147.1 - 6.5 7.1 8.2 0.78 10.0 0.9 2.5 2 1 1 3 3 3 0 54S ribosomal protein L8 C-terminal domain dsrm PF00035.26 KFX97148.1 - 3.3e-05 24.5 0.0 6.5e-05 23.6 0.0 1.5 1 0 0 1 1 1 1 Double-stranded RNA binding motif TANGO2 PF05742.12 KFX97149.1 - 5.1e-68 229.9 0.0 8.8e-68 229.1 0.0 1.3 1 0 0 1 1 1 1 Transport and Golgi organisation 2 DUF1788 PF08747.11 KFX97149.1 - 0.023 14.7 0.4 0.19 11.7 0.0 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF1788) Tfb2 PF03849.14 KFX97150.1 - 6.6e-137 456.2 0.0 9.2e-137 455.8 0.0 1.2 1 0 0 1 1 1 1 Transcription factor Tfb2 Tfb2_C PF18307.1 KFX97150.1 - 2.4e-23 82.3 0.5 4.3e-23 81.5 0.5 1.4 1 0 0 1 1 1 1 Transcription factor Tfb2 (p52) C-terminal domain Helicase_C_3 PF13625.6 KFX97150.1 - 3e-05 24.2 0.0 6.4e-05 23.1 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain 4HBT PF03061.22 KFX97151.1 - 2.9e-14 53.1 0.2 5.2e-14 52.3 0.2 1.4 1 0 0 1 1 1 1 Thioesterase superfamily DUF4442 PF14539.6 KFX97151.1 - 4.1e-05 23.7 0.0 5.7e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4442) Homeodomain PF00046.29 KFX97153.1 - 3.5e-17 62.0 3.4 7.1e-17 61.0 3.4 1.5 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 KFX97153.1 - 0.045 13.7 0.1 0.15 12.0 0.1 1.9 1 0 0 1 1 1 0 Homeobox KN domain GEN1_C PF18380.1 KFX97153.1 - 1.3 10.0 5.7 0.26 12.2 1.3 2.0 2 0 0 2 2 2 0 Holliday junction resolvase Gen1 C-terminal domain 3HCDH PF00725.22 KFX97154.1 - 8.2e-34 116.1 0.0 1.4e-33 115.4 0.0 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 3HCDH_N PF02737.18 KFX97154.1 - 1.3e-31 109.9 0.3 1.7e-31 109.5 0.3 1.2 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Suf PF05843.14 KFX97162.1 - 9 6.2 10.8 0.47 10.4 4.4 2.0 1 1 1 2 2 2 0 Suppressor of forked protein (Suf) Iso_dh PF00180.20 KFX97163.1 - 1.5e-97 326.8 0.0 2.1e-97 326.4 0.0 1.2 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Ribophorin_II PF05817.14 KFX97164.1 - 3e-22 79.0 0.0 4.3e-22 78.4 0.0 1.2 1 0 0 1 1 1 1 Oligosaccharyltransferase subunit Ribophorin II p450 PF00067.22 KFX97166.1 - 6e-74 249.5 0.0 7.7e-74 249.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 PUD1_2 PF18457.1 KFX97166.1 - 0.13 12.2 0.0 0.25 11.3 0.0 1.4 1 0 0 1 1 1 0 Up-Regulated in long-lived daf-2 NAD_binding_10 PF13460.6 KFX97167.1 - 4.4e-05 23.4 0.0 5.4e-05 23.2 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KFX97167.1 - 0.0018 17.8 0.0 0.011 15.2 0.0 1.9 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 KFX97167.1 - 0.01 15.0 0.0 0.021 14.0 0.0 1.5 1 0 0 1 1 1 0 Male sterility protein Semialdhyde_dh PF01118.24 KFX97167.1 - 0.086 13.3 0.0 0.14 12.6 0.0 1.3 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Glyco_hydro_25 PF01183.20 KFX97168.1 - 1.9e-39 135.7 0.3 2.2e-39 135.5 0.3 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 25 APH PF01636.23 KFX97169.1 - 2.6e-17 63.6 1.0 1.1e-16 61.6 0.0 2.2 2 0 0 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KFX97169.1 - 0.15 11.7 0.0 0.35 10.4 0.0 1.5 1 0 0 1 1 1 0 Choline/ethanolamine kinase HAUS6_N PF14661.6 KFX97172.1 - 1.4e-51 175.3 1.3 1.4e-51 175.3 1.3 2.4 3 1 0 3 3 3 1 HAUS augmin-like complex subunit 6 N-terminus HD_3 PF13023.6 KFX97173.1 - 6e-48 162.9 0.0 1e-47 162.2 0.0 1.3 1 0 0 1 1 1 1 HD domain HD_2 PF12917.7 KFX97173.1 - 1.6e-08 34.5 0.0 3.9e-08 33.2 0.0 1.7 1 1 0 1 1 1 1 HD containing hydrolase-like enzyme BAR_2 PF10455.9 KFX97175.1 - 5.6e-57 193.1 1.6 9.8e-57 192.3 1.6 1.3 1 1 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking BAR PF03114.18 KFX97175.1 - 5.5e-21 75.3 6.4 4e-20 72.5 6.4 1.9 1 1 0 1 1 1 1 BAR domain BAR_3 PF16746.5 KFX97175.1 - 0.0039 16.9 0.5 0.037 13.7 0.0 2.2 2 0 0 2 2 2 1 BAR domain of APPL family Arfaptin PF06456.13 KFX97175.1 - 0.033 13.7 0.1 0.093 12.3 0.1 1.7 1 0 0 1 1 1 0 Arfaptin-like domain FUSC PF04632.12 KFX97175.1 - 0.37 9.3 8.5 0.31 9.5 7.7 1.3 1 1 0 1 1 1 0 Fusaric acid resistance protein family IFT57 PF10498.9 KFX97175.1 - 0.56 9.1 7.0 1.9 7.4 2.5 2.2 2 0 0 2 2 2 0 Intra-flagellar transport protein 57 Rhodanese PF00581.20 KFX97176.1 - 1.3e-06 28.9 0.3 1.7e-05 25.2 0.3 2.4 1 1 0 1 1 1 1 Rhodanese-like domain RRM_1 PF00076.22 KFX97177.1 - 4.9e-26 90.3 0.0 8.5e-13 47.9 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RIO1 PF01163.22 KFX97178.1 - 2.3e-42 144.7 0.0 5.2e-42 143.6 0.0 1.5 1 1 0 1 1 1 1 RIO1 family Rio2_N PF09202.11 KFX97178.1 - 7.1e-29 99.9 0.1 1.4e-28 99.0 0.1 1.5 1 0 0 1 1 1 1 Rio2, N-terminal APH PF01636.23 KFX97178.1 - 1.2e-09 38.4 0.4 1.7e-05 24.9 0.1 3.0 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.14 KFX97178.1 - 2.2e-05 23.9 0.0 0.0029 17.0 0.0 2.2 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RPN1_RPN2_N PF17781.1 KFX97179.1 - 2.2e-112 375.5 1.9 3.5e-112 374.8 1.9 1.3 1 0 0 1 1 1 1 RPN1/RPN2 N-terminal domain RPN1_C PF18051.1 KFX97179.1 - 2.8e-29 100.9 0.0 5.2e-29 100.1 0.0 1.5 1 0 0 1 1 1 1 26S proteasome non-ATPase regulatory subunit RPN1 C-terminal PC_rep PF01851.22 KFX97179.1 - 2e-20 72.1 16.0 1.8e-06 28.1 0.8 8.0 8 1 0 8 8 8 4 Proteasome/cyclosome repeat HEAT_2 PF13646.6 KFX97179.1 - 1.1e-07 32.2 0.7 0.0051 17.2 0.1 4.4 4 1 1 5 5 5 3 HEAT repeats PPTA PF01239.22 KFX97180.1 - 0.19 11.5 5.1 0.39 10.5 5.1 1.5 1 0 0 1 1 1 0 Protein prenyltransferase alpha subunit repeat Mlh1_C PF16413.5 KFX97181.1 - 1e-98 330.0 0.0 1.5e-98 329.5 0.0 1.3 1 0 0 1 1 1 1 DNA mismatch repair protein Mlh1 C-terminus DNA_mis_repair PF01119.19 KFX97181.1 - 1.4e-32 111.9 0.1 3.2e-32 110.7 0.1 1.6 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.6 KFX97181.1 - 2.7e-15 56.4 0.0 6.3e-15 55.2 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 KFX97181.1 - 7.7e-07 29.6 0.0 2.2e-06 28.1 0.0 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Thioredoxin_8 PF13905.6 KFX97181.1 - 0.16 12.3 0.0 0.45 10.9 0.0 1.8 1 0 0 1 1 1 0 Thioredoxin-like zf-CRD PF17979.1 KFX97182.1 - 0.00025 21.2 4.3 0.00033 20.8 4.3 1.2 1 0 0 1 1 1 1 Cysteine rich domain with multizinc binding regions Nbs1_C PF08599.10 KFX97182.1 - 0.13 12.4 0.8 0.23 11.6 0.3 1.7 1 1 0 1 1 1 0 DNA damage repair protein Nbs1 DHHA2 PF02833.14 KFX97183.1 - 5.8e-37 127.1 0.2 8.9e-37 126.5 0.2 1.3 1 0 0 1 1 1 1 DHHA2 domain DHH PF01368.20 KFX97183.1 - 9.4e-13 48.3 0.0 3.8e-12 46.3 0.0 1.9 1 1 1 2 2 2 1 DHH family GMC_oxred_N PF00732.19 KFX97183.1 - 0.064 12.6 0.3 0.1 11.9 0.3 1.3 1 0 0 1 1 1 0 GMC oxidoreductase FMO-like PF00743.19 KFX97184.1 - 1.5e-58 198.6 0.0 2.2e-58 198.0 0.0 1.1 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 KFX97184.1 - 8.5e-16 58.1 0.0 4.9e-13 49.0 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KFX97184.1 - 9.3e-13 48.1 0.0 2.6e-12 46.6 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KFX97184.1 - 5.7e-08 32.9 0.0 1.2e-07 31.8 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.6 KFX97184.1 - 2.7e-07 30.1 0.6 7.8e-05 22.0 0.0 2.9 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.6 KFX97184.1 - 7.6e-06 26.0 0.0 0.00013 22.0 0.0 2.7 2 1 0 2 2 2 1 FAD-NAD(P)-binding DAO PF01266.24 KFX97184.1 - 3.5e-05 23.6 0.0 0.17 11.4 0.0 3.1 3 0 0 3 3 3 2 FAD dependent oxidoreductase Pyr_redox PF00070.27 KFX97184.1 - 7.3e-05 23.2 0.0 0.043 14.4 0.0 2.6 3 0 0 3 3 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KFX97184.1 - 0.0004 19.7 0.2 0.0019 17.5 0.0 2.1 3 0 0 3 3 3 1 Thi4 family NAD_binding_7 PF13241.6 KFX97184.1 - 0.0014 19.0 0.0 0.83 10.1 0.0 2.6 2 2 0 2 2 2 1 Putative NAD(P)-binding 2-Hacid_dh_C PF02826.19 KFX97184.1 - 0.0036 16.7 0.0 0.21 10.9 0.0 2.3 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain IlvN PF07991.12 KFX97184.1 - 0.034 13.7 0.0 0.31 10.6 0.0 2.4 3 0 0 3 3 3 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain Glu_dehyd_C PF16912.5 KFX97184.1 - 0.042 13.3 0.3 0.087 12.3 0.1 1.7 2 0 0 2 2 2 0 Glucose dehydrogenase C-terminus Shikimate_DH PF01488.20 KFX97184.1 - 0.066 13.3 0.4 1.4 8.9 0.0 2.6 3 0 0 3 3 2 0 Shikimate / quinate 5-dehydrogenase FAD_binding_3 PF01494.19 KFX97184.1 - 0.15 11.3 0.1 0.45 9.7 0.1 1.7 2 0 0 2 2 2 0 FAD binding domain p6 PF17548.2 KFX97184.1 - 0.16 12.0 0.0 0.39 10.7 0.0 1.7 1 1 0 1 1 1 0 Histone-like Protein p6 NAD_binding_2 PF03446.15 KFX97184.1 - 0.18 12.0 0.0 0.35 11.0 0.0 1.5 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase HI0933_like PF03486.14 KFX97184.1 - 0.21 10.2 0.0 0.33 9.6 0.0 1.2 1 0 0 1 1 1 0 HI0933-like protein DUF4431 PF14485.6 KFX97184.1 - 0.22 11.3 0.2 0.47 10.3 0.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4431) AATase PF07247.12 KFX97185.1 - 3.2e-17 62.3 0.4 3.3e-10 39.1 0.8 3.8 2 2 0 2 2 2 2 Alcohol acetyltransferase WES_acyltransf PF03007.16 KFX97185.1 - 5.5e-05 23.1 0.0 8e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 Wax ester synthase-like Acyl-CoA acyltransferase domain Condensation PF00668.20 KFX97185.1 - 0.00025 19.9 0.1 0.0031 16.3 0.0 2.0 2 0 0 2 2 2 1 Condensation domain GCP_C_terminal PF04130.13 KFX97186.1 - 3.1e-20 72.8 0.0 9.4e-20 71.3 0.0 1.7 1 1 0 1 1 1 1 Gamma tubulin complex component C-terminal GCP_N_terminal PF17681.1 KFX97186.1 - 7e-19 68.6 1.2 9.6e-19 68.1 0.1 1.6 2 0 0 2 2 2 1 Gamma tubulin complex component N-terminal HTH_ParB PF17762.1 KFX97186.1 - 0.19 11.5 1.4 17 5.3 0.1 2.5 2 0 0 2 2 2 0 HTH domain found in ParB protein ThiF PF00899.21 KFX97188.1 - 2.7e-109 364.2 0.0 5.2e-73 245.4 0.0 2.2 2 0 0 2 2 2 2 ThiF family UBA_e1_thiolCys PF10585.9 KFX97188.1 - 1.8e-93 313.1 0.2 2.6e-93 312.6 0.2 1.3 1 0 0 1 1 1 1 Ubiquitin-activating enzyme active site E1_FCCH PF16190.5 KFX97188.1 - 1.9e-30 104.8 0.1 3.9e-30 103.9 0.1 1.5 1 0 0 1 1 1 1 Ubiquitin-activating enzyme E1 FCCH domain E1_UFD PF09358.10 KFX97188.1 - 8.5e-29 100.1 0.0 1.8e-28 99.1 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin fold domain E1_4HB PF16191.5 KFX97188.1 - 2.4e-25 88.5 0.2 6.6e-25 87.1 0.2 1.8 1 0 0 1 1 1 1 Ubiquitin-activating enzyme E1 four-helix bundle Shikimate_DH PF01488.20 KFX97188.1 - 0.013 15.6 0.1 0.12 12.4 0.0 2.2 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Rad60-SLD_2 PF13881.6 KFX97189.1 - 9.9e-14 51.4 0.0 2.2e-13 50.3 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 KFX97189.1 - 2.3e-05 24.1 0.0 4.1e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family DUF2407 PF10302.9 KFX97189.1 - 0.00027 21.5 0.0 0.00067 20.2 0.0 1.6 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain DUF4592 PF15262.6 KFX97189.1 - 0.016 15.9 3.3 0.024 15.3 2.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4592) UMP1 PF05348.11 KFX97190.1 - 1.7e-39 134.7 0.0 2.1e-39 134.4 0.0 1.1 1 0 0 1 1 1 1 Proteasome maturation factor UMP1 ABC_tran PF00005.27 KFX97191.1 - 4.1e-28 98.6 0.0 1.1e-14 55.1 0.0 3.3 2 2 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 KFX97191.1 - 8.3e-13 48.8 1.3 0.0048 16.7 0.1 3.3 2 1 0 3 3 3 3 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 KFX97191.1 - 7.2e-07 29.9 1.5 0.049 14.1 1.6 2.2 2 0 0 2 2 2 2 AAA domain SbcCD_C PF13558.6 KFX97191.1 - 0.00011 22.3 0.0 0.0044 17.2 0.0 2.6 2 0 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_29 PF13555.6 KFX97191.1 - 0.00015 21.4 0.0 0.073 12.8 0.0 2.4 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_28 PF13521.6 KFX97191.1 - 0.0021 18.3 0.0 3.8 7.7 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_15 PF13175.6 KFX97191.1 - 0.0076 16.0 1.0 0.68 9.6 1.8 2.2 2 0 0 2 2 2 1 AAA ATPase domain AAA_14 PF13173.6 KFX97191.1 - 0.013 15.6 0.0 3.9 7.5 0.0 2.8 3 0 0 3 3 3 0 AAA domain AAA_24 PF13479.6 KFX97191.1 - 0.015 15.0 0.2 6.9 6.3 0.0 2.7 3 0 0 3 3 3 0 AAA domain AAA_18 PF13238.6 KFX97191.1 - 0.017 15.6 0.0 3.5 8.2 0.0 2.7 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.22 KFX97191.1 - 0.022 14.0 0.0 1.1 8.4 0.0 2.4 3 0 0 3 3 3 0 NB-ARC domain FtsK_SpoIIIE PF01580.18 KFX97191.1 - 0.033 13.5 0.0 0.8 9.0 0.0 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family MMR_HSR1 PF01926.23 KFX97191.1 - 0.045 13.8 0.0 16 5.6 0.0 2.7 2 1 0 2 2 2 0 50S ribosome-binding GTPase Pox_A32 PF04665.12 KFX97191.1 - 0.061 12.8 0.0 4.1 6.8 0.0 2.2 2 0 0 2 2 2 0 Poxvirus A32 protein AAA_16 PF13191.6 KFX97191.1 - 0.069 13.5 0.0 13 6.2 0.1 2.6 2 1 0 2 2 2 0 AAA ATPase domain NACHT PF05729.12 KFX97191.1 - 0.084 12.8 0.0 2.5 8.0 0.0 2.6 2 0 0 2 2 2 0 NACHT domain ATP-synt_ab PF00006.25 KFX97191.1 - 0.099 12.3 0.0 0.2 11.3 0.0 1.4 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain Ploopntkinase1 PF18748.1 KFX97191.1 - 0.12 11.9 0.0 0.2 11.2 0.0 1.3 1 0 0 1 1 1 0 P-loop Nucleotide Kinase1 AAA_33 PF13671.6 KFX97191.1 - 0.12 12.5 0.0 9 6.5 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_27 PF13514.6 KFX97191.1 - 0.13 11.9 0.0 2.1 7.9 0.0 2.2 2 0 0 2 2 2 0 AAA domain Tetraspanin PF00335.20 KFX97194.1 - 0.0006 19.6 4.0 0.0046 16.7 4.1 2.3 1 1 0 1 1 1 1 Tetraspanin family DUF5518 PF17647.1 KFX97194.1 - 0.014 15.5 0.7 0.014 15.5 0.7 2.6 2 1 0 2 2 2 0 Family of unknown function (DUF5518) Ycf15 PF10705.9 KFX97194.1 - 0.26 11.5 0.5 17 5.7 0.1 2.4 1 1 1 2 2 2 0 Chloroplast protein precursor Ycf15 putative APH PF01636.23 KFX97195.1 - 3.1e-07 30.6 0.0 1.1e-06 28.7 0.0 1.9 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KFX97195.1 - 0.074 12.6 0.1 0.13 11.8 0.1 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase Pkinase PF00069.25 KFX97195.1 - 0.083 12.2 0.0 0.4 10.0 0.0 1.9 2 0 0 2 2 2 0 Protein kinase domain TEX19 PF15553.6 KFX97196.1 - 0.13 12.2 0.1 0.26 11.3 0.1 1.4 1 0 0 1 1 1 0 Testis-expressed protein 19 DLH PF01738.18 KFX97198.1 - 9.1e-10 38.5 0.0 1.1e-09 38.2 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family DUF3712 PF12505.8 KFX97208.1 - 2.3e-21 76.4 1.7 2.3e-21 76.4 1.7 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF3712) Cthe_2159 PF14262.6 KFX97208.1 - 0.01 15.2 0.2 0.02 14.3 0.2 1.4 1 1 0 1 1 1 0 Carbohydrate-binding domain-containing protein Cthe_2159 Reprolysin_5 PF13688.6 KFX97214.1 - 4e-20 72.8 0.4 6.2e-20 72.2 0.4 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_4 PF13583.6 KFX97214.1 - 3.1e-16 59.6 0.1 5.2e-16 58.9 0.1 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.6 KFX97214.1 - 2e-11 44.2 0.1 3.2e-11 43.5 0.1 1.2 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Pep_M12B_propep PF01562.19 KFX97214.1 - 0.00051 20.3 0.0 0.00087 19.5 0.0 1.4 1 0 0 1 1 1 1 Reprolysin family propeptide Rgp1 PF08737.10 KFX97215.1 - 2.9e-161 537.3 0.0 4.4e-161 536.7 0.0 1.3 1 0 0 1 1 1 1 Rgp1 CRM1_C PF08767.11 KFX97215.1 - 9.7e-133 442.3 1.6 2.9e-132 440.7 0.3 2.3 2 0 0 2 2 2 1 CRM1 C terminal Xpo1 PF08389.12 KFX97215.1 - 1.1e-37 129.4 5.4 3.5e-37 127.7 3.6 2.9 3 0 0 3 3 3 1 Exportin 1-like protein CRM1_repeat_2 PF18784.1 KFX97215.1 - 1.1e-33 114.7 4.2 2.5e-33 113.5 4.2 1.7 1 0 0 1 1 1 1 CRM1 / Exportin repeat 2 CRM1_repeat_3 PF18787.1 KFX97215.1 - 4.2e-29 100.4 1.2 1.7e-28 98.4 1.2 2.2 1 0 0 1 1 1 1 CRM1 / Exportin repeat 3 CRM1_repeat PF18777.1 KFX97215.1 - 6.2e-20 70.4 1.3 1.4e-19 69.3 1.3 1.7 1 0 0 1 1 1 1 Chromosome region maintenance or exportin repeat IBN_N PF03810.19 KFX97215.1 - 2e-12 46.8 0.1 6.9e-12 45.1 0.1 2.0 1 0 0 1 1 1 1 Importin-beta N-terminal domain Sec7_N PF12783.7 KFX97215.1 - 0.029 14.3 12.1 0.5 10.2 0.2 4.1 4 2 1 5 5 5 0 Guanine nucleotide exchange factor in Golgi transport N-terminal HD_assoc PF13286.6 KFX97215.1 - 0.14 12.7 0.1 45 4.7 0.2 3.1 2 0 0 2 2 2 0 Phosphohydrolase-associated domain Arrestin_N PF00339.29 KFX97215.1 - 0.18 11.9 0.0 0.46 10.5 0.0 1.6 1 0 0 1 1 1 0 Arrestin (or S-antigen), N-terminal domain DUF3385 PF11865.8 KFX97215.1 - 0.92 9.4 6.9 0.44 10.5 0.1 3.4 4 0 0 4 4 4 0 Domain of unknown function (DUF3385) Calcipressin PF04847.12 KFX97216.1 - 1.4e-49 168.4 0.2 1.7e-49 168.1 0.2 1.1 1 0 0 1 1 1 1 Calcipressin Proteasome PF00227.26 KFX97241.1 - 1.1e-22 80.5 0.0 1.3e-22 80.2 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit TUG-UBL1 PF11470.8 KFX97242.1 - 5.3e-18 65.0 0.0 1.8e-17 63.3 0.0 2.0 2 0 0 2 2 2 1 TUG ubiquitin-like domain UBX PF00789.20 KFX97242.1 - 1.2e-07 31.8 0.6 0.027 14.7 0.0 3.3 4 0 0 4 4 4 2 UBX domain FERM_N PF09379.10 KFX97242.1 - 0.034 14.1 0.0 0.21 11.5 0.0 2.2 2 0 0 2 2 2 0 FERM N-terminal domain Ribosomal_L36e PF01158.18 KFX97243.1 - 4.9e-49 164.5 10.7 2.3e-33 114.3 3.1 2.0 2 0 0 2 2 2 2 Ribosomal protein L36e HTH_38 PF13936.6 KFX97243.1 - 0.017 14.9 1.2 0.075 12.8 0.2 2.2 2 0 0 2 2 2 0 Helix-turn-helix domain RQC PF09382.10 KFX97243.1 - 0.025 14.3 0.1 0.14 11.9 0.1 2.0 1 1 1 2 2 2 0 RQC domain TetR_C_9 PF14514.6 KFX97243.1 - 0.045 13.9 0.8 5.9 7.0 0.1 2.1 1 1 1 2 2 2 0 Tetracyclin repressor-like, C-terminal domain DAGAT PF03982.13 KFX97243.1 - 0.17 10.7 0.1 0.24 10.3 0.1 1.2 1 1 0 1 1 1 0 Diacylglycerol acyltransferase IF-2B PF01008.17 KFX97244.1 - 2e-72 243.8 0.0 3.4e-72 243.0 0.0 1.3 1 1 0 1 1 1 1 Initiation factor 2 subunit family eIF-3c_N PF05470.12 KFX97244.1 - 0.026 12.8 0.0 0.039 12.3 0.0 1.3 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus AAA PF00004.29 KFX97245.1 - 2.3e-10 41.0 0.0 5.6e-10 39.7 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KFX97245.1 - 9.9e-09 35.6 0.0 2.4e-08 34.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KFX97245.1 - 4.9e-08 33.5 0.0 2e-07 31.6 0.0 2.0 1 1 1 2 2 2 1 AAA ATPase domain Cdc6_C PF09079.11 KFX97245.1 - 1.8e-07 31.1 0.3 1.5e-06 28.0 0.3 2.3 1 1 0 1 1 1 1 CDC6, C terminal winged helix domain AAA_lid_10 PF17872.1 KFX97245.1 - 1.8e-05 24.8 0.0 6.2e-05 23.0 0.0 1.9 1 0 0 1 1 1 1 AAA lid domain AAA_19 PF13245.6 KFX97245.1 - 2.9e-05 24.5 0.1 0.00022 21.6 0.0 2.4 2 1 0 2 2 2 1 AAA domain AAA_7 PF12775.7 KFX97245.1 - 0.0037 16.8 0.0 0.012 15.2 0.0 1.8 2 0 0 2 2 2 1 P-loop containing dynein motor region ssDBP PF17878.1 KFX97245.1 - 0.006 16.8 0.0 0.015 15.5 0.0 1.6 1 0 0 1 1 1 1 Single-stranded DNA-binding protein AAA_11 PF13086.6 KFX97245.1 - 0.007 16.2 0.2 0.015 15.1 0.0 1.6 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 KFX97245.1 - 0.019 14.9 0.0 0.036 14.0 0.0 1.4 1 0 0 1 1 1 0 NACHT domain AAA_30 PF13604.6 KFX97245.1 - 0.019 14.7 0.0 0.045 13.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain TniB PF05621.11 KFX97245.1 - 0.025 14.0 0.1 0.22 10.9 0.0 2.3 3 0 0 3 3 3 0 Bacterial TniB protein RNA_helicase PF00910.22 KFX97245.1 - 0.16 12.3 0.0 0.31 11.4 0.0 1.5 1 0 0 1 1 1 0 RNA helicase PIF1 PF05970.14 KFX97245.1 - 0.2 10.8 0.0 0.31 10.1 0.0 1.2 1 0 0 1 1 1 0 PIF1-like helicase DUF2075 PF09848.9 KFX97245.1 - 0.22 10.7 0.0 0.34 10.1 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) WW PF00397.26 KFX97246.1 - 7.3e-11 42.0 0.1 1.6e-10 40.8 0.1 1.7 1 0 0 1 1 1 1 WW domain PhoD PF09423.10 KFX97246.1 - 0.0044 16.1 0.0 0.031 13.3 0.0 2.0 2 0 0 2 2 2 1 PhoD-like phosphatase PMM PF03332.13 KFX97247.1 - 2.1e-103 344.8 0.2 2.4e-103 344.7 0.2 1.0 1 0 0 1 1 1 1 Eukaryotic phosphomannomutase Ank_2 PF12796.7 KFX97254.1 - 1.6e-73 243.3 0.0 3e-12 47.0 0.0 7.3 1 1 4 6 6 6 6 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KFX97254.1 - 1.6e-45 147.8 0.0 0.0021 18.4 0.0 12.5 13 0 0 13 13 13 9 Ankyrin repeat Ank PF00023.30 KFX97254.1 - 6.8e-45 149.6 0.0 0.0046 17.4 0.0 13.1 13 0 0 13 13 12 11 Ankyrin repeat Ank_4 PF13637.6 KFX97254.1 - 7.3e-41 138.0 0.8 9.5e-07 29.3 0.0 8.3 3 3 7 10 10 10 9 Ankyrin repeats (many copies) Ank_5 PF13857.6 KFX97254.1 - 1.4e-27 95.4 1.5 0.00018 21.7 0.0 7.6 4 1 2 7 7 7 6 Ankyrin repeats (many copies) NACHT PF05729.12 KFX97254.1 - 0.00044 20.2 0.0 0.00093 19.1 0.0 1.6 1 0 0 1 1 1 1 NACHT domain ATPase PF06745.13 KFX97254.1 - 0.00069 19.0 0.4 0.0034 16.8 0.0 2.0 2 0 0 2 2 2 1 KaiC DUF2465 PF10239.9 KFX97254.1 - 0.0049 16.1 0.6 0.027 13.7 0.1 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF2465) AAA_22 PF13401.6 KFX97254.1 - 0.014 15.6 0.0 0.05 13.9 0.0 1.9 1 0 0 1 1 1 0 AAA domain Helo_like_N PF17111.5 KFX97254.1 - 0.095 12.1 0.8 0.21 10.9 0.8 1.6 1 0 0 1 1 1 0 Fungal N-terminal domain of STAND proteins SfsA PF03749.13 KFX97254.1 - 0.1 12.5 0.0 1.3e+02 2.5 0.0 4.7 4 1 1 5 5 5 0 Sugar fermentation stimulation protein RE domain Met_10 PF02475.16 KFX97255.1 - 0.0001 22.1 0.1 0.00043 20.1 0.0 1.8 2 0 0 2 2 2 1 Met-10+ like-protein DoxX_2 PF13564.6 KFX97261.1 - 0.11 12.7 0.0 0.21 11.7 0.0 1.4 1 0 0 1 1 1 0 DoxX-like family AA_permease_2 PF13520.6 KFX97272.1 - 1.4e-54 185.6 42.7 7.5e-44 150.2 30.3 3.2 2 2 1 3 3 3 2 Amino acid permease RTA1 PF04479.13 KFX97272.1 - 3e-39 134.8 2.3 3e-39 134.8 2.3 3.0 3 0 0 3 3 3 1 RTA1 like protein AA_permease PF00324.21 KFX97272.1 - 2.9e-13 49.2 37.0 2.9e-13 49.2 37.0 2.7 2 1 0 2 2 2 1 Amino acid permease APA3_viroporin PF11289.8 KFX97272.1 - 1.7 8.1 6.8 0.14 11.7 1.9 1.6 2 0 0 2 2 2 0 Coronavirus accessory protein 3a Opy2 PF09463.10 KFX97274.1 - 1.2 9.5 13.7 1.2 9.5 5.4 3.0 1 1 1 2 2 2 0 Opy2 protein GLEYA PF10528.9 KFX97275.1 - 3.1e-30 104.5 0.3 8e-30 103.1 0.3 1.8 1 0 0 1 1 1 1 GLEYA domain PAN_1 PF00024.26 KFX97275.1 - 1.9e-08 34.2 14.2 2.2e-05 24.4 1.9 2.6 2 0 0 2 2 2 2 PAN domain PA14 PF07691.12 KFX97275.1 - 4.8e-08 32.9 0.2 9.8e-08 31.9 0.2 1.5 1 0 0 1 1 1 1 PA14 domain Pyr_redox_2 PF07992.14 KFX97275.1 - 8.6e-05 21.9 0.0 0.0002 20.7 0.0 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase PAN_4 PF14295.6 KFX97275.1 - 0.0026 17.6 7.7 0.014 15.3 0.7 2.9 2 0 0 2 2 2 2 PAN domain Ion_trans_N PF08412.10 KFX97276.1 - 0.13 11.9 0.0 0.36 10.5 0.0 1.8 1 0 0 1 1 1 0 Ion transport protein N-terminal PHO4 PF01384.20 KFX97277.1 - 2.5e-101 339.1 12.7 2.9e-101 338.9 12.7 1.0 1 0 0 1 1 1 1 Phosphate transporter family ECF_trnsprt PF12822.7 KFX97277.1 - 0.0015 18.7 7.4 0.0015 18.7 7.4 3.1 2 2 0 2 2 2 1 ECF transporter, substrate-specific component Glyco_hydro_6 PF01341.17 KFX97298.1 - 0.00046 20.0 0.3 0.00055 19.8 0.3 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 6 CSN8_PSD8_EIF3K PF10075.9 KFX97299.1 - 0.00045 20.2 0.0 0.00082 19.4 0.0 1.3 1 0 0 1 1 1 1 CSN8/PSMD8/EIF3K family HlyIII PF03006.20 KFX97300.1 - 1.4e-61 208.0 13.3 1.7e-61 207.8 13.3 1.0 1 0 0 1 1 1 1 Haemolysin-III related adh_short_C2 PF13561.6 KFX97301.1 - 8.2e-47 159.7 6.5 1.4e-39 136.0 6.1 2.0 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KFX97301.1 - 1.5e-44 151.8 5.8 2e-44 151.4 5.8 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KFX97301.1 - 5.4e-16 59.0 1.2 7.5e-16 58.6 1.2 1.2 1 0 0 1 1 1 1 KR domain 3HCDH_N PF02737.18 KFX97301.1 - 0.0025 17.7 1.1 0.0036 17.2 1.1 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AdoHcyase_NAD PF00670.21 KFX97301.1 - 0.0079 16.3 1.1 0.013 15.6 0.5 1.7 2 0 0 2 2 2 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Sacchrp_dh_NADP PF03435.18 KFX97301.1 - 0.052 13.8 0.2 0.078 13.2 0.2 1.3 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Glycos_transf_2 PF00535.26 KFX97302.1 - 2.1e-30 105.8 0.0 2.5e-30 105.5 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 KFX97302.1 - 1.6e-09 38.0 0.0 2.2e-09 37.6 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.9 KFX97302.1 - 2.4e-05 24.0 0.0 3.1e-05 23.6 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.6 KFX97302.1 - 0.053 13.0 0.0 0.085 12.3 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase family 21 Glyco_tranf_2_4 PF13704.6 KFX97302.1 - 0.058 13.9 0.0 0.1 13.1 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferase family 2 TFR_dimer PF04253.15 KFX97303.1 - 4.5e-31 107.5 0.0 9.8e-31 106.4 0.0 1.5 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain Peptidase_M28 PF04389.17 KFX97303.1 - 4.1e-23 82.1 0.0 7.5e-23 81.3 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.22 KFX97303.1 - 4.3e-12 45.9 0.0 8.2e-12 45.0 0.0 1.5 1 0 0 1 1 1 1 PA domain Peptidase_M20 PF01546.28 KFX97303.1 - 0.014 15.1 0.0 0.034 13.8 0.0 1.7 1 0 0 1 1 1 0 Peptidase family M20/M25/M40 Cyt-b5 PF00173.28 KFX97304.1 - 6.2e-13 48.7 0.0 8.2e-13 48.3 0.0 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain TMA7 PF09072.10 KFX97305.1 - 3.5e-24 85.4 18.8 3.9e-24 85.2 18.8 1.0 1 0 0 1 1 1 1 Translation machinery associated TMA7 Pkinase PF00069.25 KFX97306.1 - 7.7e-54 182.8 0.1 1.1e-53 182.4 0.1 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFX97306.1 - 4.1e-24 85.3 0.2 1.2e-23 83.8 0.3 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase Pox_ser-thr_kin PF05445.11 KFX97306.1 - 0.0066 15.5 0.0 0.01 14.9 0.0 1.2 1 0 0 1 1 1 1 Poxvirus serine/threonine protein kinase RIO1 PF01163.22 KFX97306.1 - 0.063 12.9 0.2 0.16 11.5 0.2 1.7 1 1 0 1 1 1 0 RIO1 family DUF4715 PF15835.5 KFX97307.1 - 0.096 12.8 0.1 0.33 11.0 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4715) URO-D PF01208.17 KFX97315.1 - 4.5e-125 417.4 0.0 5.1e-125 417.2 0.0 1.0 1 0 0 1 1 1 1 Uroporphyrinogen decarboxylase (URO-D) PP1 PF07430.11 KFX97315.1 - 0.16 12.1 0.0 0.38 10.8 0.0 1.6 1 0 0 1 1 1 0 Phloem filament protein PP1 cystatin-like domain Ribosomal_L10 PF00466.20 KFX97316.1 - 7.8e-23 80.5 0.0 1.9e-22 79.3 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L10 RL10P_insert PF17777.1 KFX97316.1 - 7.4e-22 77.1 0.0 1.3e-21 76.3 0.0 1.4 1 0 0 1 1 1 1 Insertion domain in 60S ribosomal protein L10P Ribosomal_60s PF00428.19 KFX97316.1 - 1.3e-13 51.3 5.0 1.7e-13 51.0 2.2 2.1 2 0 0 2 2 2 1 60s Acidic ribosomal protein MutS_V PF00488.21 KFX97317.1 - 7.1e-50 169.6 0.2 1.8e-49 168.3 0.2 1.7 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 KFX97317.1 - 2.4e-20 73.6 1.1 4.1e-20 72.8 1.1 1.4 1 0 0 1 1 1 1 MutS domain III AAA_14 PF13173.6 KFX97317.1 - 0.05 13.6 0.1 0.38 10.8 0.0 2.4 2 1 0 2 2 2 0 AAA domain DUF494 PF04361.13 KFX97317.1 - 0.09 12.7 0.1 0.16 11.8 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF494) SWIRM PF04433.17 KFX97334.1 - 3.9e-13 49.6 0.0 7e-13 48.7 0.0 1.4 1 0 0 1 1 1 1 SWIRM domain ISN1 PF06437.11 KFX97342.1 - 6.6e-65 219.6 0.0 7.4e-65 219.4 0.0 1.0 1 0 0 1 1 1 1 IMP-specific 5'-nucleotidase Pex16 PF08610.10 KFX97343.1 - 4.8e-130 433.5 0.2 6.9e-130 432.9 0.2 1.2 1 0 0 1 1 1 1 Peroxisomal membrane protein (Pex16) MFS_1 PF07690.16 KFX97343.1 - 4.5e-37 127.8 22.4 4.5e-37 127.8 22.4 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KFX97343.1 - 2.7e-07 29.8 2.3 2.7e-07 29.8 2.3 1.9 3 0 0 3 3 3 1 Sugar (and other) transporter MFS_5 PF05631.14 KFX97343.1 - 0.00011 21.2 1.4 0.00019 20.5 1.4 1.3 1 0 0 1 1 1 1 Sugar-tranasporters, 12 TM MFS_1_like PF12832.7 KFX97343.1 - 0.0009 18.2 0.0 0.0034 16.3 0.0 2.1 1 1 0 1 1 1 1 MFS_1 like family Nucleos_tra2_N PF01773.20 KFX97343.1 - 0.86 10.2 6.5 13 6.4 0.1 3.8 4 0 0 4 4 4 0 Na+ dependent nucleoside transporter N-terminus F-box PF00646.33 KFX97344.1 - 9.6e-07 28.5 0.8 1.6e-06 27.8 0.8 1.4 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 KFX97344.1 - 5e-05 23.1 1.0 9.2e-05 22.3 1.0 1.5 1 0 0 1 1 1 1 F-box-like DUF1499 PF07386.11 KFX97344.1 - 0.13 12.8 0.0 0.69 10.5 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1499) SNF2_N PF00176.23 KFX97345.1 - 1.9e-58 197.8 0.1 3e-58 197.2 0.1 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KFX97345.1 - 8.2e-14 51.9 0.0 2e-13 50.7 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-C3HC4_3 PF13920.6 KFX97345.1 - 2.6e-07 30.4 3.2 4.9e-07 29.5 3.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KFX97345.1 - 5.3e-07 29.5 3.7 1.2e-06 28.5 3.7 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 KFX97345.1 - 5.4e-07 29.3 1.8 5.4e-07 29.3 1.8 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KFX97345.1 - 9.5e-07 28.6 5.5 2e-06 27.5 5.5 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) ResIII PF04851.15 KFX97345.1 - 1.2e-06 28.6 0.0 2.8e-06 27.4 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit zf-RING_2 PF13639.6 KFX97345.1 - 1.8e-05 25.0 5.1 3.4e-05 24.1 5.1 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 KFX97345.1 - 0.00015 21.7 3.9 0.00027 20.8 3.9 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 KFX97345.1 - 0.0055 16.8 7.1 0.013 15.6 7.1 1.7 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING EVC2_like PF12297.8 KFX97345.1 - 0.11 11.2 1.5 0.12 11.0 0.1 1.7 2 0 0 2 2 2 0 Ellis van Creveld protein 2 like protein Fer2 PF00111.27 KFX97345.1 - 0.16 11.9 2.6 0.64 10.0 2.8 1.9 1 1 0 1 1 1 0 2Fe-2S iron-sulfur cluster binding domain zf-RING_4 PF14570.6 KFX97345.1 - 0.36 10.6 4.5 0.96 9.3 4.5 1.7 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain Prok-RING_4 PF14447.6 KFX97345.1 - 0.55 10.1 7.0 1.9 8.4 7.0 1.9 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 BAR PF03114.18 KFX97346.1 - 6.5e-14 52.1 0.2 9.2e-14 51.7 0.2 1.2 1 0 0 1 1 1 1 BAR domain SH3_9 PF14604.6 KFX97346.1 - 2.7e-13 49.5 0.2 5.5e-13 48.5 0.2 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 KFX97346.1 - 1.8e-12 46.7 0.1 3.1e-12 45.9 0.1 1.4 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 KFX97346.1 - 4.3e-10 39.1 0.0 7.8e-10 38.3 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain Caskin-Pro-rich PF16907.5 KFX97346.1 - 0.0019 18.6 4.6 0.0053 17.2 4.6 1.7 1 0 0 1 1 1 1 Proline rich region of Caskin proteins ESP PF16590.5 KFX97346.1 - 0.068 13.4 0.4 0.19 12.0 0.4 1.9 1 0 0 1 1 1 0 Exocrine gland-secreting peptide Pex14_N PF04695.13 KFX97346.1 - 0.77 10.4 5.9 1.5 9.5 5.9 1.4 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF4449 PF14613.6 KFX97347.1 - 8.1e-10 39.0 2.9 3.3e-08 33.8 0.1 3.2 3 0 0 3 3 3 1 Protein of unknown function (DUF4449) Tricorn_C1 PF14684.6 KFX97347.1 - 0.002 18.2 0.0 0.0086 16.1 0.0 2.1 2 0 0 2 2 2 1 Tricorn protease C1 domain CPSase_L_D2 PF02786.17 KFX97348.1 - 6.9e-74 247.9 0.0 1.1e-73 247.2 0.0 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain bVLRF1 PF18826.1 KFX97348.1 - 2.7e-62 209.1 0.2 5e-62 208.2 0.2 1.5 1 0 0 1 1 1 1 bacteroidetes VLRF1 release factor Biotin_carb_C PF02785.19 KFX97348.1 - 4.2e-36 123.3 0.0 8.5e-36 122.3 0.0 1.6 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain Biotin_carb_N PF00289.22 KFX97348.1 - 7.5e-36 123.0 0.0 1.9e-35 121.8 0.0 1.7 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_lipoyl PF00364.22 KFX97348.1 - 1.3e-13 50.6 0.5 5.3e-13 48.6 0.3 2.2 2 0 0 2 2 2 1 Biotin-requiring enzyme Dala_Dala_lig_C PF07478.13 KFX97348.1 - 5.9e-09 35.7 0.0 1.3e-08 34.7 0.0 1.4 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.22 KFX97348.1 - 4.1e-07 29.7 0.0 8.4e-07 28.7 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain GARS_A PF01071.19 KFX97348.1 - 0.00028 20.7 0.1 0.00071 19.4 0.0 1.7 2 0 0 2 2 2 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain RimK PF08443.11 KFX97348.1 - 0.02 14.5 0.0 0.049 13.2 0.0 1.7 1 1 0 1 1 1 0 RimK-like ATP-grasp domain ATP-grasp_3 PF02655.14 KFX97348.1 - 0.027 14.5 0.0 0.058 13.5 0.0 1.5 1 0 0 1 1 1 0 ATP-grasp domain Ank_5 PF13857.6 KFX97348.1 - 0.033 14.5 0.0 0.076 13.4 0.0 1.6 1 0 0 1 1 1 0 Ankyrin repeats (many copies) Biotin_lipoyl_2 PF13533.6 KFX97348.1 - 0.18 11.7 0.1 4.3 7.2 0.0 2.6 1 1 1 2 2 2 0 Biotin-lipoyl like DLIC PF05783.11 KFX97349.1 - 7.5e-35 120.7 0.1 1.2e-32 113.4 0.0 3.0 3 0 0 3 3 3 2 Dynein light intermediate chain (DLIC) RRM_1 PF00076.22 KFX97350.1 - 1.8e-18 66.1 0.0 3.5e-18 65.2 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KFX97350.1 - 0.00027 21.0 0.0 0.00054 20.0 0.0 1.5 1 1 0 1 1 1 1 RNA recognition motif RRM_3 PF08777.11 KFX97350.1 - 0.17 11.9 0.4 0.59 10.2 0.0 2.0 2 0 0 2 2 2 0 RNA binding motif RRM_5 PF13893.6 KFX97350.1 - 0.19 11.3 0.0 0.33 10.6 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) WD40 PF00400.32 KFX97351.1 - 2.8e-05 24.8 0.1 0.43 11.5 0.0 3.5 3 0 0 3 3 3 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFX97351.1 - 0.03 14.6 0.0 0.58 10.5 0.0 2.6 1 1 1 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain Septin PF00735.18 KFX97352.1 - 7.1e-107 356.9 0.1 1.7e-106 355.7 0.0 1.5 2 0 0 2 2 2 1 Septin MMR_HSR1 PF01926.23 KFX97352.1 - 1.4e-06 28.4 0.0 3.3e-06 27.2 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase IIGP PF05049.13 KFX97352.1 - 0.00052 19.2 0.1 0.0011 18.2 0.1 1.4 1 0 0 1 1 1 1 Interferon-inducible GTPase (IIGP) Dynamin_N PF00350.23 KFX97352.1 - 0.00073 19.6 6.6 0.01 15.9 0.1 3.1 2 1 1 3 3 3 2 Dynamin family GTP_EFTU PF00009.27 KFX97352.1 - 0.0028 17.2 0.7 0.17 11.4 0.1 2.5 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain AIG1 PF04548.16 KFX97352.1 - 0.02 14.2 0.0 0.044 13.1 0.0 1.6 1 0 0 1 1 1 0 AIG1 family ABC_tran PF00005.27 KFX97352.1 - 0.021 15.3 0.4 0.12 12.9 0.0 2.4 2 1 0 2 2 2 0 ABC transporter Pox_A32 PF04665.12 KFX97352.1 - 0.035 13.5 0.1 0.061 12.8 0.1 1.3 1 0 0 1 1 1 0 Poxvirus A32 protein RsgA_GTPase PF03193.16 KFX97352.1 - 0.1 12.5 4.9 0.083 12.8 0.5 2.7 3 1 0 3 3 3 0 RsgA GTPase DUF87 PF01935.17 KFX97352.1 - 0.22 11.6 2.7 1.5 8.8 0.1 2.3 2 0 0 2 2 2 0 Helicase HerA, central domain Ribosomal_S17e PF00833.18 KFX97352.1 - 0.27 11.2 4.5 0.58 10.1 4.5 1.5 1 0 0 1 1 1 0 Ribosomal S17 AAA_23 PF13476.6 KFX97352.1 - 1.4 9.4 9.0 9.1 6.7 4.0 2.3 2 1 0 2 2 2 0 AAA domain Bax1-I PF01027.20 KFX97353.1 - 5.7e-51 173.3 27.5 6.5e-51 173.1 27.5 1.0 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 SH3_1 PF00018.28 KFX97354.1 - 1.6e-08 34.0 0.1 2.6e-08 33.4 0.1 1.3 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KFX97354.1 - 2.2e-06 27.4 0.0 4.1e-06 26.5 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 KFX97354.1 - 1.2e-05 24.9 0.0 2.6e-05 23.8 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain DUF2069 PF09842.9 KFX97354.1 - 1.5 9.0 7.8 0.64 10.3 3.6 2.0 2 0 0 2 2 2 0 Predicted membrane protein (DUF2069) ABC2_membrane_2 PF12679.7 KFX97354.1 - 4.9 6.4 11.5 7.5 5.7 11.5 1.3 1 0 0 1 1 1 0 ABC-2 family transporter protein Dynactin_p22 PF07426.11 KFX97355.1 - 2.2e-09 37.4 0.1 2.8e-09 37.1 0.1 1.1 1 0 0 1 1 1 1 Dynactin subunit p22 PSK_trans_fac PF07704.11 KFX97355.1 - 0.33 11.8 4.6 19 6.1 0.0 2.4 2 0 0 2 2 2 0 Rv0623-like transcription factor Aa_trans PF01490.18 KFX97356.1 - 1e-92 311.0 20.2 1.5e-92 310.5 20.2 1.2 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 KFX97356.1 - 4.4e-08 32.6 19.8 4.4e-08 32.6 19.8 1.6 2 0 0 2 2 2 1 Tryptophan/tyrosine permease family ORMDL PF04061.14 KFX97356.1 - 1.8 8.4 6.6 0.25 11.1 1.1 2.4 2 1 0 2 2 2 0 ORMDL family Ribosomal_S16 PF00886.19 KFX97357.1 - 1.8e-25 88.7 0.1 2.8e-25 88.2 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein S16 YjeF_N PF03853.15 KFX97358.1 - 1.1e-32 113.3 0.0 1.3e-32 113.0 0.0 1.1 1 0 0 1 1 1 1 YjeF-related protein N-terminus SL4P PF17618.2 KFX97358.1 - 0.027 14.5 0.1 0.047 13.7 0.1 1.3 1 0 0 1 1 1 0 Uncharacterized Strongylid L4 protein Ras PF00071.22 KFX97359.1 - 1.9e-52 177.1 0.0 2.3e-52 176.9 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFX97359.1 - 5.4e-19 68.6 0.0 7.3e-19 68.2 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFX97359.1 - 2e-10 40.4 0.0 2.2e-10 40.3 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KFX97359.1 - 8.5e-06 25.4 0.0 7.8e-05 22.3 0.0 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 KFX97359.1 - 8.8e-05 22.6 0.0 0.00014 21.9 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KFX97359.1 - 0.0015 18.4 0.0 0.69 9.8 0.0 2.3 1 1 1 2 2 2 2 RsgA GTPase G-alpha PF00503.20 KFX97359.1 - 0.018 14.2 0.0 0.021 14.0 0.0 1.2 1 0 0 1 1 1 0 G-protein alpha subunit AAA_22 PF13401.6 KFX97359.1 - 0.019 15.3 0.2 0.2 11.9 0.2 2.6 1 1 0 1 1 1 0 AAA domain RRM_1 PF00076.22 KFX97360.1 - 2.3e-16 59.4 0.0 7.9e-13 48.0 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KFX97360.1 - 0.043 13.7 0.0 0.088 12.7 0.0 1.5 1 0 0 1 1 1 0 Occluded RNA-recognition motif RRM_Rrp7 PF17799.1 KFX97360.1 - 0.082 12.7 0.0 0.56 10.0 0.0 2.1 2 0 0 2 2 2 0 Rrp7 RRM-like N-terminal domain Pro_isomerase PF00160.21 KFX97373.1 - 1.5e-19 70.9 0.0 1.7e-19 70.6 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Arrestin_C PF02752.22 KFX97374.1 - 6.1e-11 42.9 0.0 8.9e-11 42.4 0.0 1.3 1 0 0 1 1 1 1 Arrestin (or S-antigen), C-terminal domain Med3 PF11593.8 KFX97377.1 - 1.8 7.7 7.3 1.8 7.7 7.3 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal MFS_1 PF07690.16 KFX97379.1 - 8.8e-07 28.2 16.5 8.8e-07 28.2 16.5 2.0 2 0 0 2 2 2 2 Major Facilitator Superfamily FSH1 PF03959.13 KFX97380.1 - 8.7e-31 107.2 0.0 1.3e-30 106.6 0.0 1.2 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_2 PF02230.16 KFX97380.1 - 0.0026 17.6 0.0 0.0095 15.8 0.0 1.8 2 0 0 2 2 2 1 Phospholipase/Carboxylesterase PE-PPE PF08237.11 KFX97380.1 - 0.037 13.6 0.0 0.063 12.8 0.0 1.3 1 0 0 1 1 1 0 PE-PPE domain Abhydrolase_3 PF07859.13 KFX97380.1 - 0.058 13.3 0.1 0.96 9.3 0.0 2.3 3 0 0 3 3 3 0 alpha/beta hydrolase fold HscB_4_cys PF18256.1 KFX97380.1 - 4.1 7.3 6.1 1.1 9.2 0.1 2.7 3 0 0 3 3 3 0 Co-chaperone HscB tetracysteine metal binding motif Fungal_trans PF04082.18 KFX97381.1 - 6.4e-12 45.1 0.0 1.2e-11 44.2 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain TetR_C_15 PF17918.1 KFX97381.1 - 0.0054 17.5 2.7 0.047 14.4 0.3 2.7 3 0 0 3 3 3 1 Tetracyclin repressor-like, C-terminal domain DUF1529 PF07485.11 KFX97381.1 - 0.031 14.2 0.2 0.061 13.2 0.2 1.4 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1259) Kelch_5 PF13854.6 KFX97383.1 - 6.4e-10 38.8 0.1 6.4e-10 38.8 0.1 3.5 4 0 0 4 4 4 1 Kelch motif Kelch_3 PF13415.6 KFX97383.1 - 2.7e-05 24.3 2.0 0.00058 20.1 0.2 3.5 2 0 0 2 2 2 1 Galactose oxidase, central domain Kelch_1 PF01344.25 KFX97383.1 - 0.00032 20.2 0.1 0.28 10.8 0.1 3.5 2 1 0 2 2 2 2 Kelch motif stn_TNFRSF12A PF12191.8 KFX97383.1 - 0.0035 17.5 0.0 0.0082 16.4 0.0 1.6 1 0 0 1 1 1 1 Tumour necrosis factor receptor stn_TNFRSF12A_TNFR domain Kelch_6 PF13964.6 KFX97383.1 - 0.092 13.1 4.0 0.77 10.1 0.2 3.6 3 1 0 3 3 3 0 Kelch motif DUF4381 PF14316.6 KFX97383.1 - 0.1 12.9 3.1 0.24 11.7 3.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) Peptidase_M56 PF05569.11 KFX97383.1 - 0.14 11.3 0.0 0.24 10.6 0.0 1.2 1 0 0 1 1 1 0 BlaR1 peptidase M56 Stm1_N PF09598.10 KFX97384.1 - 5.9e-14 52.7 5.5 5.9e-14 52.7 5.5 4.2 3 2 1 4 4 4 1 Stm1 HABP4_PAI-RBP1 PF04774.15 KFX97384.1 - 6e-06 27.1 4.2 6e-06 27.1 4.2 2.9 2 2 1 3 3 3 1 Hyaluronan / mRNA binding family Ribosomal_L6e PF01159.19 KFX97384.1 - 0.18 12.4 3.6 0.32 11.5 3.6 1.4 1 0 0 1 1 1 0 Ribosomal protein L6e bZIP_1 PF00170.21 KFX97385.1 - 1.6e-06 28.1 5.6 1.6e-06 28.1 5.6 1.8 2 0 0 2 2 2 1 bZIP transcription factor DUF5595 PF18077.1 KFX97385.1 - 0.13 12.3 0.3 0.63 10.2 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF5595) GvpL_GvpF PF06386.11 KFX97385.1 - 0.18 11.7 2.8 0.38 10.7 2.8 1.5 1 0 0 1 1 1 0 Gas vesicle synthesis protein GvpL/GvpF DUF3890 PF13029.6 KFX97385.1 - 0.2 12.1 0.3 0.36 11.3 0.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3890) bZIP_2 PF07716.15 KFX97385.1 - 1.9 8.6 11.8 0.37 10.9 6.8 2.3 2 1 0 2 2 2 0 Basic region leucine zipper DUF4407 PF14362.6 KFX97385.1 - 2.7 7.3 5.5 3.3 7.0 3.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Nop53 PF07767.11 KFX97385.1 - 4 6.7 11.3 2.1 7.7 7.3 2.0 2 0 0 2 2 2 0 Nop53 (60S ribosomal biogenesis) WAC_Acf1_DNA_bd PF10537.9 KFX97392.1 - 1.5e-38 131.4 2.0 2e-38 130.9 0.0 2.3 2 0 0 2 2 2 1 ATP-utilising chromatin assembly and remodelling N-terminal WSD PF15613.6 KFX97392.1 - 1.9e-17 63.6 3.3 9.4e-17 61.3 0.0 3.1 2 0 0 2 2 2 1 Williams-Beuren syndrome DDT (WSD), D-TOX E motif DDT PF02791.17 KFX97392.1 - 2e-17 63.3 1.3 3.5e-17 62.4 1.3 1.4 1 0 0 1 1 1 1 DDT domain WHIM1 PF15612.6 KFX97392.1 - 1.7e-08 33.8 0.0 6.8e-08 31.9 0.0 2.0 2 0 0 2 2 2 1 WSTF, HB1, Itc1p, MBD9 motif 1 GCN5L1 PF06320.13 KFX97392.1 - 0.03 14.5 1.7 0.17 12.0 1.7 2.3 1 0 0 1 1 1 0 GCN5-like protein 1 (GCN5L1) AD PF09793.9 KFX97392.1 - 0.47 10.6 2.6 2.2 8.5 2.6 2.1 1 0 0 1 1 1 0 Anticodon-binding domain Holin_BhlA PF10960.8 KFX97392.1 - 2.6 8.1 4.6 7.2 6.7 3.7 2.2 2 0 0 2 2 2 0 BhlA holin family mRNA_cap_enzyme PF01331.19 KFX97393.1 - 2.1e-47 161.5 0.0 3.8e-47 160.7 0.0 1.4 1 0 0 1 1 1 1 mRNA capping enzyme, catalytic domain mRNA_cap_C PF03919.15 KFX97393.1 - 9.4e-36 122.7 0.3 1.9e-35 121.8 0.3 1.6 1 0 0 1 1 1 1 mRNA capping enzyme, C-terminal domain SCA7 PF08313.12 KFX97393.1 - 3.5e-30 103.7 0.2 3.5e-30 103.7 0.2 2.4 2 0 0 2 2 2 1 SCA7, zinc-binding domain DNA_ligase_A_M PF01068.21 KFX97393.1 - 0.00033 20.3 0.0 0.077 12.6 0.0 2.4 1 1 1 2 2 2 2 ATP dependent DNA ligase domain Ank_2 PF12796.7 KFX97396.1 - 5.3e-77 254.5 0.0 3.5e-15 56.4 0.0 7.4 3 2 4 7 7 7 7 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KFX97396.1 - 1.7e-50 163.1 1.9 0.0048 17.3 0.0 14.9 15 0 0 15 15 15 11 Ankyrin repeat Ank PF00023.30 KFX97396.1 - 2.4e-45 151.1 0.1 1.3e-05 25.4 0.0 14.3 15 0 0 15 15 15 8 Ankyrin repeat Ank_5 PF13857.6 KFX97396.1 - 4.3e-43 144.8 5.6 4.4e-05 23.7 0.0 11.2 5 5 7 12 12 12 10 Ankyrin repeats (many copies) Ank_4 PF13637.6 KFX97396.1 - 5.1e-41 138.5 0.0 8.7e-07 29.4 0.0 8.1 6 2 3 9 9 9 7 Ankyrin repeats (many copies) VWA_3_C PF18571.1 KFX97396.1 - 0.018 14.9 0.7 79 3.2 0.0 5.7 8 0 0 8 8 8 0 von Willebrand factor type A C-terminal domain PRELI PF04707.14 KFX97397.1 - 2.1e-43 147.9 0.5 2.4e-43 147.7 0.5 1.0 1 0 0 1 1 1 1 PRELI-like family SH3_10 PF17902.1 KFX97397.1 - 0.028 14.5 0.1 3 8.0 0.0 2.3 2 0 0 2 2 2 0 SH3 domain DUF647 PF04884.14 KFX97398.1 - 1.5e-77 260.5 0.2 2e-77 260.1 0.2 1.1 1 0 0 1 1 1 1 Vitamin B6 photo-protection and homoeostasis Importin_rep_4 PF18808.1 KFX97400.1 - 2.4e-31 107.8 0.9 2.4e-31 107.8 0.9 4.4 4 1 1 5 5 3 1 Importin repeat HEAT_EZ PF13513.6 KFX97400.1 - 3.5e-19 68.9 14.2 9.5e-11 42.0 0.4 8.0 7 1 2 9 9 8 3 HEAT-like repeat Importin_rep_6 PF18829.1 KFX97400.1 - 1.2e-15 57.5 2.5 2.7e-15 56.4 0.6 2.7 3 0 0 3 3 2 1 Importin repeat 6 HEAT PF02985.22 KFX97400.1 - 1e-14 53.4 7.2 0.0045 17.1 0.0 9.3 9 0 0 9 9 8 3 HEAT repeat HEAT_2 PF13646.6 KFX97400.1 - 1e-14 54.7 12.5 8.2e-05 22.9 0.0 7.3 4 2 1 6 6 6 3 HEAT repeats Vac14_Fab1_bd PF12755.7 KFX97400.1 - 1.3e-10 41.7 0.0 0.056 14.0 0.0 5.8 3 1 3 6 6 6 2 Vacuolar 14 Fab1-binding region MMS19_C PF12460.8 KFX97400.1 - 7.7e-08 31.9 2.2 6.7e-07 28.8 0.1 3.3 2 2 1 3 3 3 1 RNAPII transcription regulator C-terminal CLASP_N PF12348.8 KFX97400.1 - 6.5e-07 29.1 0.2 0.45 10.0 0.0 4.7 2 2 2 4 4 4 2 CLASP N terminal DUF3385 PF11865.8 KFX97400.1 - 1.8e-06 27.9 0.2 7.5 6.4 0.0 5.3 4 2 1 5 5 5 0 Domain of unknown function (DUF3385) DRIM PF07539.12 KFX97400.1 - 5.4e-05 21.7 0.3 0.81 7.9 0.0 3.7 2 2 1 3 3 3 2 Down-regulated in metastasis RIX1 PF08167.12 KFX97400.1 - 0.00027 20.7 0.0 0.017 14.9 0.0 3.9 4 1 0 4 4 4 1 rRNA processing/ribosome biogenesis Arm PF00514.23 KFX97400.1 - 0.0011 19.0 4.2 0.15 12.1 0.1 4.5 4 0 0 4 4 3 1 Armadillo/beta-catenin-like repeat Adaptin_N PF01602.20 KFX97400.1 - 0.0012 17.5 0.9 0.073 11.6 0.1 2.4 2 0 0 2 2 2 1 Adaptin N terminal region Dopey_N PF04118.14 KFX97400.1 - 0.0022 17.1 0.8 2.2 7.3 0.0 3.4 3 1 0 3 3 3 2 Dopey, N-terminal IBN_N PF03810.19 KFX97400.1 - 0.0026 17.6 1.1 0.014 15.3 0.1 3.0 3 0 0 3 3 2 1 Importin-beta N-terminal domain IKBKB_SDD PF18397.1 KFX97400.1 - 0.0085 15.4 0.0 0.026 13.8 0.0 1.8 1 0 0 1 1 1 1 IQBAL scaffold dimerization domain Cnd3 PF12719.7 KFX97400.1 - 0.0092 15.2 0.0 0.21 10.7 0.0 2.9 2 1 0 2 2 2 1 Nuclear condensing complex subunits, C-term domain RTP1_C1 PF10363.9 KFX97400.1 - 0.012 15.8 0.2 1.7 8.9 0.1 3.9 3 0 0 3 3 3 0 Required for nuclear transport of RNA pol II C-terminus 1 MMS19_N PF14500.6 KFX97400.1 - 0.021 14.4 0.2 8.6 5.8 0.1 3.5 4 0 0 4 4 3 0 Dos2-interacting transcription regulator of RNA-Pol-II DNA_alkylation PF08713.11 KFX97400.1 - 0.042 13.6 0.1 0.17 11.6 0.0 2.1 2 0 0 2 2 2 0 DNA alkylation repair enzyme Gcn1_N PF12074.8 KFX97400.1 - 0.091 12.0 0.0 11 5.2 0.0 2.9 2 0 0 2 2 2 0 Generalcontrol nonderepressible 1 (Gcn1) N-terminal Phage_Gp23 PF10669.9 KFX97400.1 - 0.11 12.9 0.1 0.25 11.7 0.1 1.5 1 0 0 1 1 1 0 Protein gp23 (Bacteriophage A118) V-ATPase_H_N PF03224.14 KFX97400.1 - 0.21 10.9 0.8 3.1 7.0 0.0 2.4 2 1 0 2 2 2 0 V-ATPase subunit H YtxH PF12732.7 KFX97400.1 - 0.35 11.4 1.7 2.7 8.6 0.6 2.6 2 0 0 2 2 2 0 YtxH-like protein DALR_1 PF05746.15 KFX97400.1 - 0.88 9.8 6.9 6.6 6.9 0.1 4.2 3 1 1 4 4 4 0 DALR anticodon binding domain Clathrin_lg_ch PF01086.17 KFX97400.1 - 1.7 8.7 6.4 0.38 10.8 2.6 1.8 2 0 0 2 2 2 0 Clathrin light chain adh_short PF00106.25 KFX97401.1 - 1.3e-20 73.8 0.0 9.5e-19 67.6 0.0 2.1 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 KFX97401.1 - 3.5e-13 49.7 0.0 9.6e-12 44.9 0.0 2.1 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KFX97401.1 - 1.9e-10 40.9 0.0 3.1e-10 40.2 0.0 1.3 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 KFX97401.1 - 0.00066 18.9 0.0 0.00095 18.4 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Epimerase PF01370.21 KFX97401.1 - 0.0013 18.2 0.0 0.0028 17.2 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Sacchrp_dh_NADP PF03435.18 KFX97401.1 - 0.021 15.1 0.1 0.038 14.3 0.1 1.4 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain DUF3842 PF12953.7 KFX97401.1 - 0.031 14.7 0.3 0.078 13.4 0.2 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3842) Semialdhyde_dh PF01118.24 KFX97401.1 - 0.043 14.2 0.0 0.09 13.2 0.0 1.5 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain GDP_Man_Dehyd PF16363.5 KFX97401.1 - 0.069 12.5 0.0 0.11 11.9 0.0 1.2 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase RRM_1 PF00076.22 KFX97404.1 - 1.1e-40 137.2 0.0 3.2e-20 71.7 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KFX97404.1 - 0.0002 21.4 0.0 0.097 12.8 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif Nup35_RRM_2 PF14605.6 KFX97404.1 - 0.0091 16.0 0.0 0.47 10.5 0.0 2.4 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif Ribosomal_L37 PF08561.10 KFX97405.1 - 3.2e-40 137.4 0.4 6.7e-40 136.3 0.4 1.5 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L37 TAFII55_N PF04658.13 KFX97406.1 - 1.3e-50 171.2 0.0 2.1e-50 170.6 0.0 1.3 1 0 0 1 1 1 1 TAFII55 protein conserved region YgaB PF14182.6 KFX97406.1 - 0.19 12.1 0.2 0.49 10.8 0.2 1.7 1 1 0 1 1 1 0 YgaB-like protein Alg6_Alg8 PF03155.15 KFX97407.1 - 1.5e-129 433.1 30.3 1.2e-81 275.1 12.6 2.3 2 1 0 2 2 2 2 ALG6, ALG8 glycosyltransferase family Smim3 PF17307.2 KFX97407.1 - 6.5 6.3 7.6 6.4 6.4 0.0 3.4 4 0 0 4 4 4 0 Small integral membrane protein 3 2-Hacid_dh_C PF02826.19 KFX97409.1 - 1.5e-52 177.5 0.0 2.7e-52 176.7 0.0 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 KFX97409.1 - 4.5e-35 120.2 0.4 6.5e-35 119.7 0.4 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain ACT PF01842.25 KFX97409.1 - 0.00033 20.4 0.0 0.0013 18.5 0.0 2.0 1 0 0 1 1 1 1 ACT domain AlaDh_PNT_C PF01262.21 KFX97409.1 - 0.0016 17.8 0.8 0.026 13.8 0.5 2.4 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain AdoHcyase_NAD PF00670.21 KFX97409.1 - 0.02 15.0 0.2 0.057 13.5 0.2 1.7 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain XdhC_C PF13478.6 KFX97409.1 - 0.022 15.3 0.0 0.067 13.7 0.0 1.9 1 0 0 1 1 1 0 XdhC Rossmann domain Lipase_GDSL_2 PF13472.6 KFX97410.1 - 2.5e-15 57.3 0.4 3.2e-15 57.0 0.4 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 KFX97410.1 - 2.1e-05 24.6 0.1 5.7e-05 23.2 0.1 1.8 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_3 PF14606.6 KFX97410.1 - 0.0021 18.2 0.0 0.0029 17.8 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family OSK PF17182.4 KFX97410.1 - 0.0065 15.7 0.0 0.0089 15.3 0.0 1.1 1 0 0 1 1 1 1 OSK domain Ribosomal_S8 PF00410.19 KFX97412.1 - 0.0021 18.0 0.0 0.0031 17.5 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S8 APH PF01636.23 KFX97426.1 - 1e-09 38.7 0.0 3.7e-09 36.9 0.0 2.0 1 1 1 2 2 2 1 Phosphotransferase enzyme family DEAD PF00270.29 KFX97428.1 - 6e-08 32.6 0.0 1.5e-07 31.3 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 KFX97428.1 - 0.0071 16.4 0.0 0.024 14.6 0.0 1.9 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit GTP_EFTU PF00009.27 KFX97440.1 - 2.4e-58 196.9 0.3 3.7e-58 196.3 0.3 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 KFX97440.1 - 7.1e-34 116.2 0.1 1.5e-33 115.2 0.1 1.6 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_II PF14492.6 KFX97440.1 - 2.7e-33 113.9 0.0 5.5e-33 112.9 0.0 1.5 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_C PF00679.24 KFX97440.1 - 1.3e-24 86.0 0.0 2.1e-23 82.2 0.0 2.4 2 0 0 2 2 2 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 KFX97440.1 - 5.7e-13 49.1 0.0 1.3e-12 47.9 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 RF3_C PF16658.5 KFX97440.1 - 3.8e-07 30.0 0.0 7.7e-07 29.0 0.0 1.5 1 0 0 1 1 1 1 Class II release factor RF3, C-terminal domain AvrPtoB_bdg PF16847.5 KFX97440.1 - 0.1 13.1 0.0 4 8.0 0.0 2.5 2 0 0 2 2 2 0 Avirulence AvrPtoB, BAK1-binding domain MMR_HSR1 PF01926.23 KFX97440.1 - 0.12 12.5 0.0 0.22 11.6 0.0 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase DUF2569 PF10754.9 KFX97441.1 - 0.0079 16.6 1.1 0.0079 16.6 1.1 2.5 3 1 0 3 3 3 1 Protein of unknown function (DUF2569) Abhydrolase_6 PF12697.7 KFX97442.1 - 7.3e-05 23.5 2.4 7.3e-05 23.5 2.4 1.9 2 2 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KFX97442.1 - 0.016 14.8 0.0 0.026 14.2 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_3 PF07859.13 KFX97442.1 - 0.018 14.9 0.2 0.037 13.9 0.1 1.5 1 1 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_8 PF06259.12 KFX97442.1 - 0.093 12.4 0.1 0.16 11.6 0.1 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase Hydrolase_4 PF12146.8 KFX97442.1 - 0.18 11.0 0.0 0.31 10.3 0.0 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Aldo_ket_red PF00248.21 KFX97443.1 - 8.6e-53 179.4 0.0 1.2e-52 178.9 0.0 1.2 1 0 0 1 1 1 1 Aldo/keto reductase family Fructosamin_kin PF03881.14 KFX97443.1 - 2e-40 138.8 0.0 2.8e-40 138.4 0.0 1.1 1 0 0 1 1 1 1 Fructosamine kinase Frtz PF11768.8 KFX97444.1 - 8.6e-08 30.9 0.1 0.0085 14.5 0.0 2.5 3 0 0 3 3 3 2 WD repeat-containing and planar cell polarity effector protein Fritz DUF676 PF05057.14 KFX97444.1 - 1.6e-07 31.1 0.0 4.1e-07 29.7 0.0 1.6 1 0 0 1 1 1 1 Putative serine esterase (DUF676) WD40 PF00400.32 KFX97444.1 - 1.2e-06 29.1 0.0 1.1 10.2 0.0 6.6 6 0 0 6 6 6 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFX97444.1 - 6.8e-06 26.3 0.0 2 8.8 0.0 5.1 4 1 1 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain PGAP1 PF07819.13 KFX97444.1 - 4.7e-05 23.2 0.0 0.0001 22.1 0.0 1.4 1 0 0 1 1 1 1 PGAP1-like protein NACHT PF05729.12 KFX97444.1 - 0.00026 20.9 0.2 0.0011 18.9 0.0 2.1 2 0 0 2 2 2 1 NACHT domain Abhydrolase_6 PF12697.7 KFX97444.1 - 0.0015 19.2 0.0 0.0034 18.0 0.0 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family AAA_19 PF13245.6 KFX97444.1 - 0.11 12.8 0.0 0.69 10.2 0.0 2.4 1 1 0 1 1 1 0 AAA domain VID27 PF08553.10 KFX97444.1 - 0.12 11.5 0.0 9.9 5.1 0.0 2.3 2 0 0 2 2 2 0 VID27 C-terminal WD40-like domain DAO PF01266.24 KFX97445.1 - 2.2e-32 113.0 1.5 2.5e-32 112.8 1.5 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 KFX97445.1 - 0.00062 19.8 0.1 0.022 14.8 0.1 2.2 2 0 0 2 2 2 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 KFX97445.1 - 0.019 15.2 0.1 0.051 13.8 0.1 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Shikimate_DH PF01488.20 KFX97445.1 - 0.23 11.5 0.0 0.48 10.5 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Glyco_transf_54 PF04666.13 KFX97446.1 - 7e-08 31.7 0.0 0.0066 15.4 0.1 3.1 3 0 0 3 3 3 2 N-Acetylglucosaminyltransferase-IV (GnT-IV) conserved region EF-hand_6 PF13405.6 KFX97446.1 - 2.2e-05 24.0 1.2 0.00066 19.4 0.3 2.7 2 0 0 2 2 2 1 EF-hand domain EF-hand_1 PF00036.32 KFX97446.1 - 6.1e-05 22.3 3.0 0.00056 19.3 0.4 3.0 3 0 0 3 3 3 1 EF hand EF-hand_7 PF13499.6 KFX97446.1 - 0.0001 22.6 0.2 0.00035 20.9 0.3 2.0 2 1 0 2 2 2 1 EF-hand domain pair EF-hand_5 PF13202.6 KFX97446.1 - 0.00034 20.0 2.3 0.015 14.8 0.9 2.4 2 0 0 2 2 2 1 EF hand Type_ISP_C PF18135.1 KFX97446.1 - 0.013 14.5 0.0 0.022 13.8 0.0 1.3 1 0 0 1 1 1 0 Type ISP C-terminal specificity domain Glyco_transf_25 PF01755.17 KFX97446.1 - 0.1 12.5 0.0 0.23 11.3 0.0 1.6 1 0 0 1 1 1 0 Glycosyltransferase family 25 (LPS biosynthesis protein) ADH_zinc_N_2 PF13602.6 KFX97447.1 - 2.6e-27 96.5 0.4 5.1e-27 95.5 0.4 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 KFX97447.1 - 4.9e-16 58.9 0.3 1.5e-15 57.3 0.1 1.8 1 1 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KFX97447.1 - 6.3e-06 26.0 0.0 2.1e-05 24.3 0.0 1.9 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain Pyr_redox_2 PF07992.14 KFX97448.1 - 2.1e-45 155.2 0.3 3e-45 154.7 0.3 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KFX97448.1 - 3.5e-20 72.4 0.3 3.5e-20 72.4 0.3 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 KFX97448.1 - 6.3e-20 71.5 0.0 1.3e-19 70.5 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GIDA PF01134.22 KFX97448.1 - 6.9e-08 32.0 8.6 0.0018 17.4 0.8 3.6 2 1 2 4 4 4 2 Glucose inhibited division protein A Lycopene_cycl PF05834.12 KFX97448.1 - 3e-07 29.8 7.5 0.064 12.3 0.2 3.2 3 0 0 3 3 3 3 Lycopene cyclase protein Pyr_redox_3 PF13738.6 KFX97448.1 - 2.2e-06 27.2 0.4 5e-05 22.7 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KFX97448.1 - 1.8e-05 23.6 9.7 0.0058 15.4 0.3 3.2 2 1 1 3 3 3 2 HI0933-like protein 3HCDH_N PF02737.18 KFX97448.1 - 0.0002 21.3 2.9 0.023 14.6 0.2 2.5 2 0 0 2 2 2 2 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_binding_2 PF00890.24 KFX97448.1 - 0.00049 19.3 4.9 0.014 14.5 0.8 2.6 2 0 0 2 2 2 2 FAD binding domain NAD_binding_7 PF13241.6 KFX97448.1 - 0.0026 18.1 0.6 0.027 14.9 0.1 2.3 2 0 0 2 2 2 1 Putative NAD(P)-binding 2-Hacid_dh_C PF02826.19 KFX97448.1 - 0.0032 16.9 0.0 0.021 14.2 0.0 2.2 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.14 KFX97448.1 - 0.0045 16.6 1.8 0.032 13.8 0.1 2.2 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NAD_binding_8 PF13450.6 KFX97448.1 - 0.018 15.3 2.5 1.2 9.4 0.2 2.5 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 KFX97448.1 - 0.055 12.7 0.9 0.49 9.6 0.1 2.3 2 0 0 2 2 2 0 Thi4 family TrkA_N PF02254.18 KFX97448.1 - 0.083 13.2 0.6 0.88 9.9 0.0 2.5 2 0 0 2 2 2 0 TrkA-N domain ThiF PF00899.21 KFX97448.1 - 0.14 11.5 0.9 0.35 10.2 0.1 2.0 3 0 0 3 3 3 0 ThiF family zf-C2H2 PF00096.26 KFX97449.1 - 1.6e-11 44.0 27.9 0.0032 17.9 3.7 4.9 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFX97449.1 - 2.9e-09 37.0 23.7 0.006 17.3 2.7 5.0 4 0 0 4 4 4 3 C2H2-type zinc finger zf-C2H2_6 PF13912.6 KFX97449.1 - 0.00012 22.0 8.4 0.00014 21.8 1.6 2.9 2 0 0 2 2 2 1 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KFX97449.1 - 0.015 15.7 24.9 0.058 13.9 0.6 4.7 4 0 0 4 4 4 0 Zinc-finger double domain zf-C2H2_jaz PF12171.8 KFX97449.1 - 2.1 8.7 13.8 3.1 8.2 0.8 3.8 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding Pro_dh PF01619.18 KFX97451.1 - 5.6e-65 219.8 1.4 6.6e-65 219.5 1.4 1.0 1 0 0 1 1 1 1 Proline dehydrogenase Stimulus_sens_1 PF13756.6 KFX97451.1 - 0.0068 17.0 0.0 0.017 15.7 0.0 1.6 1 0 0 1 1 1 1 Stimulus-sensing domain DUF1387 PF07139.11 KFX97453.1 - 0.061 13.1 0.8 0.064 13.0 0.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1387) DUF1127 PF06568.11 KFX97454.1 - 6.5 6.6 10.2 1.1 9.0 6.5 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF1127) He_PIG PF05345.12 KFX97460.1 - 3e-16 59.3 18.1 4.5e-06 26.8 3.1 4.8 4 0 0 4 4 4 4 Putative Ig domain Methyltransf_16 PF10294.9 KFX97461.1 - 2.3e-44 151.2 0.0 3.4e-44 150.6 0.0 1.2 1 0 0 1 1 1 1 Lysine methyltransferase GMC_oxred_N PF00732.19 KFX97462.1 - 1.4e-22 80.5 0.0 1.1e-18 67.7 0.0 2.8 2 1 0 2 2 2 2 GMC oxidoreductase GMC_oxred_C PF05199.13 KFX97462.1 - 1.5e-12 48.3 0.1 3.2e-12 47.2 0.1 1.6 1 1 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 KFX97462.1 - 5.6e-06 25.7 2.4 0.00089 18.4 1.5 2.2 2 0 0 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.14 KFX97462.1 - 0.0011 18.3 0.1 0.0047 16.2 0.1 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KFX97462.1 - 0.0017 17.5 0.7 0.0031 16.6 0.7 1.4 1 0 0 1 1 1 1 Lycopene cyclase protein DAO PF01266.24 KFX97462.1 - 0.0019 17.8 0.6 0.03 13.9 0.2 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KFX97462.1 - 0.002 18.3 0.2 0.0054 16.9 0.2 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 KFX97462.1 - 0.0022 16.7 0.2 0.0032 16.2 0.2 1.2 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox_3 PF13738.6 KFX97462.1 - 0.0027 17.0 0.9 0.0054 16.0 0.9 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KFX97462.1 - 0.012 14.9 0.2 0.024 13.9 0.2 1.4 1 0 0 1 1 1 0 Thi4 family FAD_oxidored PF12831.7 KFX97462.1 - 0.018 14.4 0.5 0.03 13.7 0.2 1.5 2 0 0 2 2 2 0 FAD dependent oxidoreductase GIDA PF01134.22 KFX97462.1 - 0.033 13.3 0.1 0.047 12.8 0.1 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A FAD_binding_3 PF01494.19 KFX97462.1 - 0.094 11.9 0.3 0.13 11.4 0.3 1.2 1 0 0 1 1 1 0 FAD binding domain ABC_tran PF00005.27 KFX97470.1 - 1.9e-49 167.7 0.0 5.6e-30 104.7 0.0 2.6 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 KFX97470.1 - 7.5e-40 137.3 14.4 3.4e-23 82.7 5.3 3.4 3 0 0 3 3 3 2 ABC transporter transmembrane region SMC_N PF02463.19 KFX97470.1 - 3.7e-10 39.6 0.0 0.0026 17.2 0.1 4.1 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 KFX97470.1 - 5e-05 23.7 1.9 0.37 11.2 0.1 3.7 3 0 0 3 3 3 1 AAA ATPase domain RIO1 PF01163.22 KFX97470.1 - 0.00014 21.5 0.1 0.00025 20.7 0.1 1.3 1 0 0 1 1 1 1 RIO1 family T2SSE PF00437.20 KFX97470.1 - 0.00019 20.6 0.0 0.08 12.0 0.0 2.3 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_29 PF13555.6 KFX97470.1 - 0.00065 19.4 0.0 1.3 8.9 0.1 2.8 3 0 0 3 3 2 2 P-loop containing region of AAA domain AAA_23 PF13476.6 KFX97470.1 - 0.00085 19.9 0.1 0.071 13.6 0.0 2.6 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.23 KFX97470.1 - 0.0022 18.1 0.3 0.14 12.2 0.0 2.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_21 PF13304.6 KFX97470.1 - 0.0028 17.5 6.2 8.9 6.0 0.4 4.3 2 2 2 4 4 4 0 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 KFX97470.1 - 0.0032 17.4 0.0 1.8 8.5 0.0 2.4 2 0 0 2 2 2 1 RsgA GTPase AAA_22 PF13401.6 KFX97470.1 - 0.0038 17.5 0.3 8 6.7 0.0 3.3 2 1 0 2 2 2 1 AAA domain APH PF01636.23 KFX97470.1 - 0.0038 17.2 0.0 0.034 14.1 0.0 2.3 1 1 1 2 2 2 1 Phosphotransferase enzyme family Pkinase PF00069.25 KFX97470.1 - 0.0043 16.5 0.1 0.0082 15.5 0.1 1.4 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.14 KFX97470.1 - 0.015 14.7 0.1 0.032 13.6 0.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF87 PF01935.17 KFX97470.1 - 0.018 15.2 1.8 0.46 10.5 0.0 2.5 2 0 0 2 2 2 0 Helicase HerA, central domain AAA_25 PF13481.6 KFX97470.1 - 0.023 14.3 0.0 1.1 8.8 0.0 2.6 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 KFX97470.1 - 0.051 12.9 0.1 5.8 6.1 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin DUF2075 PF09848.9 KFX97470.1 - 0.065 12.5 0.2 0.7 9.1 0.0 2.1 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA_15 PF13175.6 KFX97470.1 - 0.2 11.3 0.0 23 4.6 0.0 2.3 2 0 0 2 2 2 0 AAA ATPase domain NACHT PF05729.12 KFX97470.1 - 1.3 8.9 4.1 1.8 8.5 0.1 2.9 3 0 0 3 3 3 0 NACHT domain cobW PF02492.19 KFX97470.1 - 1.4 8.5 3.0 2 8.0 0.4 2.4 3 0 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain Raffinose_syn PF05691.12 KFX97471.1 - 2.9e-49 167.6 1.8 2.4e-47 161.2 1.3 2.7 2 1 0 2 2 2 1 Raffinose synthase or seed imbibition protein Sip1 tRNA-synt_1b PF00579.25 KFX97472.1 - 5.2e-76 255.8 0.0 7e-76 255.3 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) TyrRSs_C PF16714.5 KFX97472.1 - 9e-43 144.9 0.1 2.1e-42 143.7 0.1 1.6 2 0 0 2 2 2 1 Tyrosyl-tRNA synthetase C-terminal domain TFIID_20kDa PF03847.13 KFX97474.1 - 1.4e-22 80.0 0.0 1.9e-22 79.5 0.0 1.2 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A CBFD_NFYB_HMF PF00808.23 KFX97474.1 - 0.00047 20.4 0.0 0.0014 18.9 0.0 1.7 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 KFX97474.1 - 0.038 14.3 0.3 0.13 12.7 0.0 1.9 2 0 0 2 2 2 0 Core histone H2A/H2B/H3/H4 TFIID-18kDa PF02269.16 KFX97474.1 - 0.19 11.8 0.0 0.32 11.0 0.0 1.3 1 0 0 1 1 1 0 Transcription initiation factor IID, 18kD subunit KTI12 PF08433.10 KFX97485.1 - 4.9e-57 193.5 0.0 7.1e-57 192.9 0.0 1.3 1 1 0 1 1 1 1 Chromatin associated protein KTI12 TPP_enzyme_N PF02776.18 KFX97487.1 - 2.5e-40 137.9 0.0 5.9e-40 136.7 0.0 1.7 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.22 KFX97487.1 - 7e-36 123.0 0.1 1.5e-35 121.9 0.1 1.6 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.21 KFX97487.1 - 8.6e-20 71.1 0.0 2.4e-19 69.6 0.0 1.8 1 1 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain B12-binding PF02310.19 KFX97487.1 - 0.0077 16.3 0.3 0.03 14.4 0.3 2.0 1 0 0 1 1 1 1 B12 binding domain CO_dh PF02552.16 KFX97487.1 - 0.045 13.5 0.0 0.087 12.6 0.0 1.4 1 0 0 1 1 1 0 CO dehydrogenase beta subunit/acetyl-CoA synthase epsilon subunit SH3BGR PF04908.15 KFX97488.1 - 0.00027 21.0 0.0 0.001 19.2 0.0 2.0 1 0 0 1 1 1 1 SH3-binding, glutamic acid-rich protein Hamartin PF04388.12 KFX97488.1 - 0.089 11.4 12.0 0.11 11.1 12.0 1.2 1 0 0 1 1 1 0 Hamartin protein Nop14 PF04147.12 KFX97488.1 - 0.88 7.7 45.6 1.2 7.3 45.6 1.2 1 0 0 1 1 1 0 Nop14-like family Mpp10 PF04006.12 KFX97488.1 - 0.99 7.8 39.6 1.4 7.3 39.6 1.2 1 0 0 1 1 1 0 Mpp10 protein SAPS PF04499.15 KFX97488.1 - 2.8 6.6 18.4 3.3 6.4 18.4 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein 3Beta_HSD PF01073.19 KFX97489.1 - 1.9e-67 227.2 0.0 2.4e-67 226.9 0.0 1.0 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 KFX97489.1 - 4.2e-29 101.7 0.1 5.5e-29 101.3 0.1 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 KFX97489.1 - 1.8e-14 53.5 0.0 2.4e-14 53.1 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain GDP_Man_Dehyd PF16363.5 KFX97489.1 - 4.5e-14 52.6 0.2 7e-12 45.4 0.1 2.5 2 1 0 2 2 2 1 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.12 KFX97489.1 - 5.9e-12 45.3 0.1 1.8e-08 33.9 0.0 2.1 2 0 0 2 2 2 2 Male sterility protein NAD_binding_10 PF13460.6 KFX97489.1 - 2.6e-10 40.5 0.0 3.9e-10 39.9 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Polysacc_synt_2 PF02719.15 KFX97489.1 - 4.2e-10 39.2 0.5 1e-09 38.0 0.5 1.7 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NmrA PF05368.13 KFX97489.1 - 0.00012 21.7 0.0 0.00017 21.2 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family TrkA_N PF02254.18 KFX97489.1 - 0.00087 19.5 0.1 0.0017 18.6 0.1 1.5 1 0 0 1 1 1 1 TrkA-N domain KR PF08659.10 KFX97489.1 - 0.0014 18.6 0.2 0.0053 16.7 0.2 2.0 1 1 0 1 1 1 1 KR domain NAD_binding_3 PF03447.16 KFX97489.1 - 0.0072 17.0 0.0 0.015 15.9 0.0 1.5 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain Glyco_trans_4_2 PF13477.6 KFX97489.1 - 0.018 15.0 0.0 0.037 14.0 0.0 1.5 1 0 0 1 1 1 0 Glycosyl transferase 4-like BsuBI_PstI_RE PF06616.11 KFX97489.1 - 0.044 13.1 0.0 0.076 12.3 0.0 1.3 1 0 0 1 1 1 0 BsuBI/PstI restriction endonuclease domain Guanylate_kin PF00625.21 KFX97489.1 - 0.051 13.3 0.0 0.12 12.1 0.0 1.5 1 0 0 1 1 1 0 Guanylate kinase ELMO_CED12 PF04727.13 KFX97490.1 - 8.4e-50 169.3 0.1 1.8e-49 168.3 0.0 1.6 2 0 0 2 2 2 1 ELMO/CED-12 family PH_12 PF16457.5 KFX97490.1 - 4.7e-34 117.8 0.0 1.1e-33 116.6 0.0 1.7 1 0 0 1 1 1 1 Pleckstrin homology domain DUF3361 PF11841.8 KFX97490.1 - 7.7e-14 51.9 0.0 2e-13 50.5 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF3361) CBM_1 PF00734.18 KFX97491.1 - 1.2e-10 41.2 16.0 1.2e-10 41.2 16.0 2.6 4 0 0 4 4 4 1 Fungal cellulose binding domain Peptidase_S9 PF00326.21 KFX97491.1 - 1.1e-05 25.1 0.1 1.8e-05 24.3 0.1 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Esterase PF00756.20 KFX97491.1 - 2.2e-05 24.3 1.0 0.00018 21.3 1.0 2.1 1 1 0 1 1 1 1 Putative esterase Esterase_phd PF10503.9 KFX97491.1 - 0.00032 20.3 0.1 0.00064 19.3 0.1 1.5 1 0 0 1 1 1 1 Esterase PHB depolymerase Abhydrolase_2 PF02230.16 KFX97491.1 - 0.0089 15.9 0.0 0.014 15.2 0.0 1.2 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_1 PF00561.20 KFX97491.1 - 0.0097 15.6 0.0 0.017 14.8 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold LtrA PF06772.11 KFX97492.1 - 3.5e-26 92.3 24.1 3.5e-26 92.3 24.1 1.9 2 0 0 2 2 2 1 Bacterial low temperature requirement A protein (LtrA) ApoLp-III PF07464.11 KFX97492.1 - 0.014 15.5 0.4 0.024 14.7 0.4 1.4 1 0 0 1 1 1 0 Apolipophorin-III precursor (apoLp-III) PsaL PF02605.15 KFX97492.1 - 0.089 12.4 2.7 4.5 6.9 0.1 3.0 3 0 0 3 3 3 0 Photosystem I reaction centre subunit XI Baculo_PEP_C PF04513.12 KFX97492.1 - 0.15 12.1 3.5 0.69 10.0 3.4 2.0 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF5344 PF17279.2 KFX97492.1 - 1.1 9.8 4.7 5.5 7.6 3.8 2.2 1 1 1 2 2 2 0 Family of unknown function (DUF5344) Alpha-amylase PF00128.24 KFX97493.1 - 1.1e-17 64.6 0.0 1.4e-16 61.0 0.0 2.1 1 1 0 1 1 1 1 Alpha amylase, catalytic domain Alpha-amylase_C PF02806.18 KFX97493.1 - 3.2e-10 40.3 0.1 8.2e-10 39.0 0.1 1.7 1 0 0 1 1 1 1 Alpha amylase, C-terminal all-beta domain MFS_1 PF07690.16 KFX97494.1 - 2.2e-23 82.8 57.1 4e-23 81.9 57.1 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily LAM_C PF12544.8 KFX97495.1 - 0.00024 21.3 0.1 0.00055 20.1 0.1 1.6 1 0 0 1 1 1 1 Lysine-2,3-aminomutase Radical_SAM PF04055.21 KFX97495.1 - 0.01 16.2 0.0 0.037 14.4 0.0 2.0 2 1 0 2 2 2 0 Radical SAM superfamily Mce4_CUP1 PF11887.8 KFX97495.1 - 0.032 13.7 1.3 0.21 11.0 0.0 2.2 1 1 1 2 2 2 0 Cholesterol uptake porter CUP1 of Mce4, putative Fer4_14 PF13394.6 KFX97495.1 - 0.048 13.8 0.0 0.087 13.0 0.0 1.4 1 0 0 1 1 1 0 4Fe-4S single cluster domain zf-GRF PF06839.12 KFX97496.1 - 4e-10 39.6 5.1 9.8e-10 38.4 5.1 1.7 1 0 0 1 1 1 1 GRF zinc finger FAD_binding_2 PF00890.24 KFX97497.1 - 3e-125 418.6 3.2 3.8e-125 418.3 3.2 1.1 1 0 0 1 1 1 1 FAD binding domain Succ_DH_flav_C PF02910.20 KFX97497.1 - 1.8e-43 147.5 0.5 2.8e-43 147.0 0.5 1.3 1 0 0 1 1 1 1 Fumarate reductase flavoprotein C-term Pyr_redox_2 PF07992.14 KFX97497.1 - 6.5e-06 25.6 0.8 0.0016 17.8 0.3 2.8 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 KFX97497.1 - 1.1e-05 24.7 0.8 0.012 14.7 1.7 2.2 2 0 0 2 2 2 2 Glucose inhibited division protein A Thi4 PF01946.17 KFX97497.1 - 9.2e-05 21.8 0.4 0.035 13.3 0.1 2.3 2 0 0 2 2 2 2 Thi4 family FAD_binding_3 PF01494.19 KFX97497.1 - 0.0026 17.0 0.6 0.0058 15.9 0.1 1.7 2 0 0 2 2 2 1 FAD binding domain DAO PF01266.24 KFX97497.1 - 0.067 12.8 1.7 0.26 10.8 1.6 2.0 1 1 0 1 1 1 0 FAD dependent oxidoreductase HI0933_like PF03486.14 KFX97497.1 - 0.078 11.7 1.0 0.31 9.7 0.4 2.2 3 0 0 3 3 3 0 HI0933-like protein Pyr_redox_3 PF13738.6 KFX97497.1 - 0.95 8.7 2.3 2.9 7.1 1.2 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DUF3818 PF12825.7 KFX97498.1 - 8e-130 432.8 7.4 8e-130 432.8 7.4 1.7 2 0 0 2 2 2 1 Domain of unknown function in PX-proteins (DUF3818) PXB PF12828.7 KFX97498.1 - 2e-38 131.3 1.2 4.6e-38 130.1 1.2 1.6 1 0 0 1 1 1 1 PX-associated PX PF00787.24 KFX97498.1 - 8.6e-07 28.9 1.5 2e-06 27.8 0.2 2.3 2 1 0 2 2 2 1 PX domain Myc_N PF01056.18 KFX97498.1 - 0.012 15.5 1.1 0.012 15.5 1.1 2.3 2 0 0 2 2 2 0 Myc amino-terminal region DUF16 PF01519.16 KFX97498.1 - 0.25 11.8 2.3 1.4 9.5 2.3 2.3 1 0 0 1 1 1 0 Protein of unknown function DUF16 WASH_WAHD PF11945.8 KFX97498.1 - 0.83 9.1 5.9 0.63 9.5 0.7 2.4 2 0 0 2 2 2 0 WAHD domain of WASH complex CSRNP_N PF16019.5 KFX97498.1 - 1 9.2 5.8 5.2 6.9 1.2 2.5 2 0 0 2 2 2 0 Cysteine/serine-rich nuclear protein N-terminus DUF4337 PF14235.6 KFX97498.1 - 1.1 9.3 4.4 0.27 11.3 0.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4337) DUF745 PF05335.13 KFX97498.1 - 3.8 7.2 6.0 23 4.6 1.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF745) eIF-5a PF01287.20 KFX97503.1 - 3.3e-15 55.9 0.1 7.6e-15 54.8 0.1 1.5 2 0 0 2 2 2 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold EFP_N PF08207.12 KFX97503.1 - 0.0013 18.7 0.0 0.0022 18.0 0.0 1.4 1 0 0 1 1 1 1 Elongation factor P (EF-P) KOW-like domain 3HCDH_N PF02737.18 KFX97504.1 - 3.6e-08 33.5 0.5 4.5e-08 33.2 0.5 1.1 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_2 PF03446.15 KFX97504.1 - 0.0033 17.6 0.1 0.0044 17.2 0.1 1.1 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase DAO PF01266.24 KFX97504.1 - 0.0034 17.0 0.8 0.0042 16.7 0.8 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase 2-Hacid_dh_C PF02826.19 KFX97504.1 - 0.01 15.2 0.0 0.01 15.2 0.0 1.1 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_8 PF13450.6 KFX97504.1 - 0.037 14.2 0.3 0.064 13.5 0.3 1.4 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain UDPG_MGDP_dh_N PF03721.14 KFX97504.1 - 0.042 13.4 0.1 0.052 13.1 0.1 1.1 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Pyr_redox_2 PF07992.14 KFX97504.1 - 0.043 13.1 0.1 0.043 13.1 0.1 1.0 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.16 KFX97504.1 - 0.055 13.1 0.5 0.07 12.8 0.5 1.2 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Sacchrp_dh_NADP PF03435.18 KFX97504.1 - 0.056 13.7 0.2 0.071 13.4 0.2 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain TIMELESS PF04821.14 KFX97505.1 - 2.2e-88 296.1 0.0 5.5e-88 294.8 0.0 1.7 1 0 0 1 1 1 1 Timeless protein TIMELESS_C PF05029.13 KFX97505.1 - 1.7e-33 116.6 3.1 1.7e-33 116.6 3.1 2.9 2 1 1 3 3 3 2 Timeless protein C terminal region DUF3388 PF11868.8 KFX97505.1 - 0.0032 16.8 0.0 0.0066 15.8 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3388) DALR_2 PF09190.11 KFX97505.1 - 0.0068 16.9 0.3 0.043 14.3 0.2 2.4 2 0 0 2 2 2 1 DALR domain KAP PF05804.12 KFX97506.1 - 0.00015 20.1 0.0 0.018 13.2 0.0 2.1 2 0 0 2 2 2 2 Kinesin-associated protein (KAP) V-ATPase_H_N PF03224.14 KFX97506.1 - 0.048 13.0 0.1 0.11 11.8 0.1 1.6 1 0 0 1 1 1 0 V-ATPase subunit H Arm PF00514.23 KFX97506.1 - 0.061 13.4 0.1 57 4.0 0.0 4.3 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat RICTOR_V PF14668.6 KFX97506.1 - 0.14 12.4 0.0 11 6.3 0.0 2.8 2 0 0 2 2 2 0 Rapamycin-insensitive companion of mTOR, domain 5 CDRN PF05174.12 KFX97506.1 - 0.63 9.8 4.0 16 5.3 0.0 3.9 4 0 0 4 4 4 0 Cysteine-rich D. radiodurans N terminus DPM3 PF08285.11 KFX97507.1 - 9.8e-36 121.8 0.1 1.4e-35 121.4 0.1 1.2 1 0 0 1 1 1 1 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) Striatin PF08232.12 KFX97507.1 - 0.041 14.5 0.1 0.053 14.1 0.1 1.1 1 0 0 1 1 1 0 Striatin family CENP-P PF13096.6 KFX97508.1 - 0.011 15.5 0.0 0.011 15.5 0.0 1.0 1 0 0 1 1 1 0 CENP-A-nucleosome distal (CAD) centromere subunit, CENP-P bZIP_1 PF00170.21 KFX97509.1 - 6.2e-09 35.8 7.8 1.4e-08 34.7 7.8 1.5 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 KFX97509.1 - 2.7e-05 24.2 7.3 9.4e-05 22.4 7.3 1.9 1 1 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.17 KFX97509.1 - 0.00046 20.6 9.6 0.001 19.6 9.6 1.5 1 0 0 1 1 1 1 bZIP Maf transcription factor SPX PF03105.19 KFX97509.1 - 0.17 11.8 11.4 0.24 11.3 11.4 1.2 1 0 0 1 1 1 0 SPX domain Macoilin PF09726.9 KFX97509.1 - 0.41 9.1 6.2 0.54 8.8 6.2 1.1 1 0 0 1 1 1 0 Macoilin family tRNA-synt_2 PF00152.20 KFX97532.1 - 1.3e-57 195.3 0.0 1.8e-57 194.8 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 KFX97532.1 - 0.00092 19.2 0.0 0.0018 18.2 0.0 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain DUF2263 PF10021.9 KFX97533.1 - 1.7e-15 57.6 0.0 2.5e-15 57.1 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2263) Fungal_trans PF04082.18 KFX97534.1 - 2.2e-10 40.0 1.3 7.2e-10 38.3 0.8 2.0 2 0 0 2 2 2 1 Fungal specific transcription factor domain MFS_1 PF07690.16 KFX97535.1 - 3.6e-23 82.1 60.4 4.5e-18 65.3 27.6 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 KFX97535.1 - 0.00017 20.6 8.7 0.00017 20.6 8.7 2.5 1 1 1 3 3 3 2 MFS_1 like family Trp_oprn_chp PF09534.10 KFX97535.1 - 0.49 10.2 4.7 27 4.5 0.0 3.4 3 1 0 3 3 3 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) RAP1 PF07218.11 KFX97536.1 - 0.083 11.2 10.9 0.11 10.8 10.9 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Sugar_tr PF00083.24 KFX97537.1 - 1.2e-56 192.4 26.4 1.5e-56 192.2 26.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KFX97537.1 - 4.9e-22 78.3 26.8 6.9e-22 77.8 26.8 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Glyco_hyd_65N_2 PF14498.6 KFX97538.1 - 3.8e-63 213.5 0.0 5.2e-63 213.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 65, N-terminal domain Glyco_hydro_1 PF00232.18 KFX97539.1 - 8.5e-144 479.3 0.3 1e-143 479.1 0.3 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 1 Cupin_1 PF00190.22 KFX97540.1 - 0.0039 16.8 0.0 0.0051 16.4 0.0 1.1 1 0 0 1 1 1 1 Cupin Sulfatase PF00884.23 KFX97541.1 - 2.4e-15 56.7 0.0 4.1e-15 56.0 0.0 1.4 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.22 KFX97541.1 - 7.3e-05 22.5 0.0 0.00015 21.4 0.0 1.6 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase DUF229 PF02995.17 KFX97541.1 - 0.13 10.9 0.1 0.18 10.3 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF229) Zn_clus PF00172.18 KFX97542.1 - 0.00086 19.4 19.1 0.0015 18.6 19.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RsbU_N PF08673.10 KFX97542.1 - 0.16 12.1 0.0 0.34 11.0 0.0 1.6 1 0 0 1 1 1 0 Phosphoserine phosphatase RsbU, N-terminal domain Fungal_trans PF04082.18 KFX97543.1 - 1.8e-13 50.1 0.0 3.8e-13 49.1 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain MFS_1 PF07690.16 KFX97544.1 - 1.2e-16 60.6 21.2 1.8e-14 53.5 14.1 2.3 3 0 0 3 3 3 2 Major Facilitator Superfamily WD40 PF00400.32 KFX97549.1 - 7e-17 61.5 5.4 0.0022 18.8 0.0 5.3 5 0 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFX97549.1 - 2.1e-06 27.9 0.0 0.0031 17.8 0.0 4.4 3 3 3 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KFX97549.1 - 0.00081 18.2 0.0 0.0072 15.0 0.0 2.0 2 0 0 2 2 2 1 Nucleoporin Nup120/160 WD40_like PF17005.5 KFX97549.1 - 0.00082 18.8 0.0 0.0021 17.4 0.0 1.6 2 0 0 2 2 2 1 WD40-like domain Ge1_WD40 PF16529.5 KFX97549.1 - 0.15 11.0 0.2 0.52 9.2 0.0 2.0 3 0 0 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Beta-lactamase PF00144.24 KFX97558.1 - 1.6e-41 142.7 0.1 2e-41 142.3 0.1 1.1 1 0 0 1 1 1 1 Beta-lactamase Peptidase_S11 PF00768.20 KFX97558.1 - 0.0098 15.3 0.4 0.016 14.7 0.4 1.3 1 0 0 1 1 1 1 D-alanyl-D-alanine carboxypeptidase Beta-lactamase2 PF13354.6 KFX97558.1 - 0.12 12.0 0.0 0.24 11.0 0.0 1.5 1 0 0 1 1 1 0 Beta-lactamase enzyme family CDH-cyt PF16010.5 KFX97561.1 - 5.2e-59 199.0 0.9 2.1e-58 197.0 0.2 2.1 2 0 0 2 2 2 1 Cytochrome domain of cellobiose dehydrogenase GMC_oxred_N PF00732.19 KFX97561.1 - 8e-27 94.4 0.1 1.5e-26 93.4 0.1 1.5 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KFX97561.1 - 1e-22 81.2 0.2 1.8e-22 80.4 0.2 1.4 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 KFX97561.1 - 1.2e-08 34.5 0.3 0.004 16.3 0.0 2.5 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 KFX97561.1 - 0.0026 18.0 0.1 0.01 16.1 0.0 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KFX97561.1 - 0.0032 17.1 0.3 0.052 13.1 0.0 2.4 3 0 0 3 3 3 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KFX97561.1 - 0.0052 16.1 2.2 0.015 14.5 0.0 2.4 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 KFX97561.1 - 0.0096 15.3 0.0 0.028 13.8 0.0 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.14 KFX97561.1 - 0.029 13.1 0.0 0.042 12.6 0.0 1.2 1 0 0 1 1 1 0 HI0933-like protein Pyr_redox PF00070.27 KFX97561.1 - 0.035 14.7 0.2 0.092 13.3 0.0 1.8 2 0 0 2 2 1 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KFX97561.1 - 0.07 12.4 0.2 0.19 10.9 0.2 1.6 1 0 0 1 1 1 0 Thi4 family RNHCP PF12647.7 KFX97561.1 - 0.18 11.8 0.0 0.35 10.9 0.0 1.3 1 0 0 1 1 1 0 RNHCP domain GIDA PF01134.22 KFX97561.1 - 0.83 8.7 3.2 1.1 8.3 0.1 2.5 3 0 0 3 3 3 0 Glucose inhibited division protein A Glyco_hydro_61 PF03443.14 KFX97562.1 - 4.5e-62 209.6 0.1 5.5e-62 209.4 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Glyco_hydro_61 PF03443.14 KFX97563.1 - 5.9e-50 170.1 0.0 7e-50 169.8 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Glyco_hydro_6 PF01341.17 KFX97564.1 - 9e-106 354.0 2.3 1.1e-105 353.7 2.3 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 6 CBM_1 PF00734.18 KFX97564.1 - 2.8e-12 46.4 12.8 2.8e-12 46.4 12.8 2.7 3 0 0 3 3 3 1 Fungal cellulose binding domain Toxin_7 PF05980.12 KFX97564.1 - 4.6 7.6 10.9 0.061 13.6 2.4 2.3 3 0 0 3 3 3 0 Toxin 7 Glyco_hydro_61 PF03443.14 KFX97565.1 - 4.6e-43 147.5 0.0 6.9e-43 147.0 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 DUF4334 PF14232.6 KFX97566.1 - 0.021 14.8 0.0 7.3 6.6 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4334) Cpn60_TCP1 PF00118.24 KFX97567.1 - 3.9e-148 494.1 7.4 4.4e-148 494.0 7.4 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family TetR_C_14 PF17754.1 KFX97567.1 - 0.015 15.3 0.1 1.1 9.2 0.1 2.5 2 0 0 2 2 2 0 MftR C-terminal domain Chromo_shadow PF01393.19 KFX97569.1 - 0.031 14.4 0.0 0.076 13.1 0.0 1.6 1 0 0 1 1 1 0 Chromo shadow domain Iwr1 PF08574.10 KFX97570.1 - 7.9e-13 49.2 9.3 7.9e-13 49.2 9.3 3.3 2 1 1 3 3 3 2 Transcription factor Iwr1 DUF4598 PF15370.6 KFX97570.1 - 0.29 11.6 7.2 1.6 9.2 7.2 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF4598) SMI1_KNR4 PF09346.10 KFX97571.1 - 0.0017 18.7 0.0 0.0046 17.4 0.0 1.8 2 0 0 2 2 2 1 SMI1 / KNR4 family (SUKH-1) GST_N_3 PF13417.6 KFX97572.1 - 1.2e-09 38.4 0.1 4.5e-09 36.6 0.1 1.8 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KFX97572.1 - 2.2e-09 37.5 0.0 3.8e-09 36.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KFX97572.1 - 7.5e-06 25.9 0.0 1.7e-05 24.8 0.0 1.6 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KFX97572.1 - 0.021 15.0 0.0 0.041 14.1 0.0 1.5 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 KFX97572.1 - 0.086 13.2 0.0 0.18 12.2 0.0 1.6 1 1 0 1 1 1 0 Glutathione S-transferase, N-terminal domain Not3 PF04065.15 KFX97573.1 - 0.0062 16.0 1.1 0.046 13.2 0.1 2.2 2 0 0 2 2 2 1 Not1 N-terminal domain, CCR4-Not complex component Mfa1 PF17445.2 KFX97573.1 - 0.16 12.0 2.0 0.49 10.4 2.0 1.8 1 0 0 1 1 1 0 Mating factor A1 DUF5082 PF16888.5 KFX97573.1 - 0.61 10.4 4.3 26 5.1 0.2 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF5082) TPR_MLP1_2 PF07926.12 KFX97573.1 - 1.1 9.4 5.0 4.8 7.3 0.5 3.2 3 0 0 3 3 3 0 TPR/MLP1/MLP2-like protein Prefoldin_2 PF01920.20 KFX97573.1 - 2.3 8.2 10.0 32 4.6 0.0 3.4 3 0 0 3 3 3 0 Prefoldin subunit FA_desaturase PF00487.24 KFX97576.1 - 2e-22 80.3 23.2 5.8e-22 78.8 23.2 1.7 1 1 0 1 1 1 1 Fatty acid desaturase DUF3474 PF11960.8 KFX97576.1 - 2.2e-05 24.7 0.0 4.2e-05 23.8 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3474) ABC_tran PF00005.27 KFX97579.1 - 6.6e-33 114.1 0.1 4.1e-20 72.7 0.0 3.1 3 0 0 3 3 2 2 ABC transporter ABC_tran_Xtn PF12848.7 KFX97579.1 - 2.4e-23 81.9 4.6 6.6e-22 77.3 3.4 2.8 2 0 0 2 2 2 1 ABC transporter AAA_21 PF13304.6 KFX97579.1 - 6.8e-13 49.1 0.0 0.00057 19.8 0.0 3.3 3 0 0 3 3 3 3 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 KFX97579.1 - 1e-07 32.7 6.3 0.0065 17.0 0.0 3.7 4 1 0 4 4 3 2 AAA domain AAA_29 PF13555.6 KFX97579.1 - 1.3e-07 31.2 0.8 0.0017 18.0 0.2 2.4 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_15 PF13175.6 KFX97579.1 - 1.6e-07 31.4 0.1 0.014 15.1 0.0 2.7 2 1 0 2 2 2 2 AAA ATPase domain RsgA_GTPase PF03193.16 KFX97579.1 - 4.6e-07 29.9 0.6 0.00097 19.1 0.1 3.0 3 0 0 3 3 3 1 RsgA GTPase SMC_N PF02463.19 KFX97579.1 - 7.7e-06 25.5 0.0 0.25 10.8 0.0 3.4 3 0 0 3 3 3 2 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 KFX97579.1 - 2.9e-05 24.1 0.1 0.036 14.1 0.0 3.0 3 0 0 3 3 2 1 50S ribosome-binding GTPase RNA_helicase PF00910.22 KFX97579.1 - 4.1e-05 23.9 2.5 0.8 10.1 0.1 3.4 3 0 0 3 3 3 2 RNA helicase AAA_18 PF13238.6 KFX97579.1 - 7.1e-05 23.4 0.3 0.73 10.4 0.0 2.9 3 0 0 3 3 2 2 AAA domain AAA_24 PF13479.6 KFX97579.1 - 7.7e-05 22.5 0.6 0.96 9.1 0.1 3.2 3 0 0 3 3 3 2 AAA domain AAA_16 PF13191.6 KFX97579.1 - 7.8e-05 23.1 0.0 0.072 13.5 0.0 2.6 2 0 0 2 2 2 1 AAA ATPase domain AAA_28 PF13521.6 KFX97579.1 - 7.9e-05 22.9 0.1 0.035 14.4 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 KFX97579.1 - 0.00027 21.2 0.0 0.4 11.0 0.1 2.7 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 KFX97579.1 - 0.00075 19.5 0.7 1.2 9.1 0.0 2.6 2 0 0 2 2 2 2 NACHT domain AAA_5 PF07728.14 KFX97579.1 - 0.0015 18.6 0.2 0.59 10.1 0.2 2.5 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA PF00004.29 KFX97579.1 - 0.0015 19.0 0.1 1.4 9.4 0.1 3.3 3 0 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) NB-ARC PF00931.22 KFX97579.1 - 0.0021 17.3 0.2 0.38 9.9 0.0 3.3 3 0 0 3 3 3 1 NB-ARC domain AAA_27 PF13514.6 KFX97579.1 - 0.0033 17.0 0.9 2.2 7.8 0.0 3.2 3 1 0 3 3 3 1 AAA domain AAA_33 PF13671.6 KFX97579.1 - 0.0036 17.5 0.4 1.3 9.1 0.2 3.3 3 0 0 3 3 2 1 AAA domain Rad17 PF03215.15 KFX97579.1 - 0.0055 16.6 0.0 3.9 7.4 0.0 2.5 2 0 0 2 2 2 1 Rad17 P-loop domain Roc PF08477.13 KFX97579.1 - 0.0091 16.2 0.0 4.3 7.6 0.1 2.7 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase DUF2813 PF11398.8 KFX97579.1 - 0.0094 15.2 0.2 6 6.0 0.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF2813) AAA_17 PF13207.6 KFX97579.1 - 0.022 15.2 0.1 7.3 7.0 0.0 2.9 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 KFX97579.1 - 0.031 13.8 0.0 1.6 8.2 0.0 2.5 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_25 PF13481.6 KFX97579.1 - 0.031 13.8 0.1 0.57 9.7 0.0 2.5 2 0 0 2 2 2 0 AAA domain VirE PF05272.11 KFX97579.1 - 0.035 13.8 0.0 7 6.3 0.0 2.9 3 0 0 3 3 3 0 Virulence-associated protein E MCM PF00493.23 KFX97579.1 - 0.04 13.0 0.0 5 6.1 0.0 2.4 2 0 0 2 2 2 0 MCM P-loop domain DAP3 PF10236.9 KFX97579.1 - 0.047 12.9 0.4 9 5.4 0.0 2.9 2 1 1 3 3 3 0 Mitochondrial ribosomal death-associated protein 3 AAA_14 PF13173.6 KFX97579.1 - 0.047 13.7 0.0 8.7 6.4 0.0 2.7 2 0 0 2 2 2 0 AAA domain FeoB_N PF02421.18 KFX97579.1 - 0.062 12.8 0.0 2.7 7.5 0.0 2.8 3 0 0 3 3 2 0 Ferrous iron transport protein B MeaB PF03308.16 KFX97579.1 - 0.063 12.2 0.1 6.3 5.7 0.0 2.5 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB DUF815 PF05673.13 KFX97579.1 - 0.073 12.2 0.3 8.9 5.4 0.0 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF815) TsaE PF02367.17 KFX97579.1 - 0.085 12.9 0.8 5.8 6.9 0.0 2.9 3 0 0 3 3 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE PduV-EutP PF10662.9 KFX97579.1 - 0.091 12.5 0.7 18 5.0 0.0 3.3 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation G-alpha PF00503.20 KFX97579.1 - 0.099 11.8 0.4 2.4 7.2 0.0 2.5 3 0 0 3 3 3 0 G-protein alpha subunit DUF87 PF01935.17 KFX97579.1 - 0.1 12.7 0.1 20 5.2 0.0 2.9 3 0 0 3 3 2 0 Helicase HerA, central domain NTPase_1 PF03266.15 KFX97579.1 - 0.24 11.3 2.9 1.4 8.8 0.2 3.0 3 0 0 3 3 3 0 NTPase AAA_30 PF13604.6 KFX97579.1 - 0.31 10.7 0.1 0.31 10.7 0.1 3.0 4 0 0 4 4 2 0 AAA domain DUF3450 PF11932.8 KFX97579.1 - 2.3 7.4 5.8 1.8 7.8 0.1 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF3450) Dynamin_N PF00350.23 KFX97579.1 - 4.7 7.2 7.0 12 5.9 0.0 3.5 4 1 1 5 5 4 0 Dynamin family Zn_clus PF00172.18 KFX97580.1 - 2.8e-05 24.2 9.4 4.7e-05 23.4 9.4 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.16 KFX97581.1 - 8.2e-42 143.4 42.4 1.9e-41 142.2 42.4 1.7 1 0 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 KFX97581.1 - 1.2e-11 43.8 21.9 1.8e-11 43.2 21.9 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 KFX97581.1 - 2.6e-11 43.1 16.4 2.6e-11 43.1 16.4 2.2 2 0 0 2 2 2 1 Sugar (and other) transporter DUF2499 PF10693.9 KFX97581.1 - 0.051 13.9 0.3 0.59 10.4 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2499) Zn_clus PF00172.18 KFX97582.1 - 7.9e-09 35.5 9.3 1.7e-08 34.5 9.3 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KFX97582.1 - 1.1e-06 27.8 0.0 1.5e-06 27.4 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain adh_short PF00106.25 KFX97583.1 - 5.2e-39 133.7 0.0 7.1e-39 133.3 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KFX97583.1 - 2.5e-26 92.7 0.0 3.4e-26 92.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KFX97583.1 - 4.2e-09 36.6 0.1 9.3e-09 35.4 0.1 1.5 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.10 KFX97583.1 - 0.00013 21.4 0.0 0.00016 21.2 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) NAD_binding_10 PF13460.6 KFX97583.1 - 0.00038 20.4 0.0 0.00057 19.8 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KFX97583.1 - 0.00066 19.2 0.1 0.0015 18.1 0.1 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 KFX97583.1 - 0.016 14.3 0.0 0.025 13.7 0.0 1.2 1 0 0 1 1 1 0 RmlD substrate binding domain NmrA PF05368.13 KFX97583.1 - 0.033 13.7 0.1 0.05 13.1 0.1 1.2 1 0 0 1 1 1 0 NmrA-like family MUG113 PF13455.6 KFX97584.1 - 3.5e-26 91.7 0.1 9.4e-26 90.3 0.1 1.8 1 0 0 1 1 1 1 Meiotically up-regulated gene 113 T5orf172 PF10544.9 KFX97584.1 - 2.8e-25 88.8 0.6 1.1e-24 86.9 0.0 2.2 2 1 0 2 2 2 1 T5orf172 domain Radical_SAM_C PF16199.5 KFX97585.1 - 3.2e-32 110.4 0.0 6.6e-32 109.4 0.0 1.6 1 0 0 1 1 1 1 Radical_SAM C-terminal domain Radical_SAM PF04055.21 KFX97585.1 - 1.8e-16 60.9 0.0 5.2e-16 59.5 0.0 1.7 1 0 0 1 1 1 1 Radical SAM superfamily Acetyltransf_1 PF00583.25 KFX97585.1 - 5e-09 36.4 0.0 9.5e-09 35.5 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KFX97585.1 - 1.4e-06 28.3 0.1 3.5e-06 27.0 0.0 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KFX97585.1 - 0.011 16.2 0.0 0.024 15.1 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain CoA_binding PF02629.19 KFX97586.1 - 3.6e-27 94.9 3.3 4.6e-27 94.5 1.2 2.1 2 0 0 2 2 2 1 CoA binding domain Ligase_CoA PF00549.19 KFX97586.1 - 2.8e-23 82.4 0.1 4.7e-23 81.7 0.1 1.4 1 0 0 1 1 1 1 CoA-ligase Succ_CoA_lig PF13607.6 KFX97586.1 - 1.2e-09 38.0 0.0 2.2e-09 37.2 0.0 1.4 1 0 0 1 1 1 1 Succinyl-CoA ligase like flavodoxin domain CoA_binding_2 PF13380.6 KFX97586.1 - 0.00011 22.7 0.4 0.00038 20.9 0.1 2.1 3 0 0 3 3 3 1 CoA binding domain CFEM PF05730.11 KFX97588.1 - 8.2e-14 51.5 13.8 1.3e-13 50.8 13.8 1.3 1 0 0 1 1 1 1 CFEM domain RPN2_C PF18004.1 KFX97590.1 - 2e-58 196.9 1.5 3.7e-58 196.0 1.5 1.5 1 0 0 1 1 1 1 26S proteasome regulatory subunit RPN2 C-terminal domain PC_rep PF01851.22 KFX97590.1 - 1.9e-40 135.2 20.5 1.3e-08 34.8 0.0 8.2 8 0 0 8 8 8 7 Proteasome/cyclosome repeat HEAT_2 PF13646.6 KFX97590.1 - 1.8e-22 79.5 0.2 5.5e-16 58.7 0.0 5.8 3 1 0 5 5 5 2 HEAT repeats HEAT_EZ PF13513.6 KFX97590.1 - 2.1e-07 31.3 1.0 0.00026 21.4 0.1 5.2 4 1 1 5 5 5 2 HEAT-like repeat HEAT PF02985.22 KFX97590.1 - 8.9e-06 25.5 2.2 1.4 9.4 0.0 5.9 6 0 0 6 6 6 1 HEAT repeat Cnd1 PF12717.7 KFX97590.1 - 0.01 15.9 0.1 0.66 10.0 0.0 3.0 2 0 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1 mRNA_triPase PF02940.15 KFX97591.1 - 1.9e-59 201.0 0.1 2.8e-59 200.5 0.1 1.2 1 0 0 1 1 1 1 mRNA capping enzyme, beta chain Hid1 PF12722.7 KFX97591.1 - 3.8 5.5 4.2 9.2 4.3 4.2 1.6 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Glyco_hydro_20 PF00728.22 KFX97592.1 - 2e-104 349.8 0.4 5.6e-103 345.0 0.5 2.1 2 0 0 2 2 2 1 Glycosyl hydrolase family 20, catalytic domain Pkinase PF00069.25 KFX97592.1 - 2.1e-42 145.3 0.0 1.1e-41 143.0 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFX97592.1 - 8.7e-31 107.1 0.0 1.3e-30 106.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Glycohydro_20b2 PF14845.6 KFX97592.1 - 1.1e-25 90.9 0.0 2.7e-25 89.6 0.0 1.7 1 0 0 1 1 1 1 beta-acetyl hexosaminidase like Glyco_hydro_20b PF02838.15 KFX97592.1 - 0.003 18.3 0.0 0.0068 17.2 0.0 1.6 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, domain 2 Kinase-like PF14531.6 KFX97592.1 - 0.034 13.5 0.0 0.054 12.8 0.0 1.2 1 0 0 1 1 1 0 Kinase-like Kdo PF06293.14 KFX97592.1 - 0.051 12.9 0.0 0.1 11.9 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 KFX97592.1 - 0.068 11.9 0.0 0.11 11.3 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase PP1_bind PF15276.6 KFX97592.1 - 0.19 12.1 0.8 0.56 10.6 0.8 1.8 1 0 0 1 1 1 0 Protein phosphatase 1 binding Acyl_transf_3 PF01757.22 KFX97593.1 - 3.3e-29 102.0 26.9 3.6e-28 98.6 26.9 2.0 1 1 0 1 1 1 1 Acyltransferase family Cation_ATPase_C PF00689.21 KFX97593.1 - 3.3 7.4 7.6 10 5.8 0.3 3.1 2 2 1 3 3 3 0 Cation transporting ATPase, C-terminus FMN_dh PF01070.18 KFX97594.1 - 0.16 10.9 0.0 0.19 10.8 0.0 1.0 1 0 0 1 1 1 0 FMN-dependent dehydrogenase SET PF00856.28 KFX97595.1 - 7.2e-11 42.8 0.5 2.1e-10 41.2 0.5 1.9 1 1 0 1 1 1 1 SET domain Meleagrin PF08189.11 KFX97595.1 - 0.0021 17.7 0.7 0.006 16.2 0.7 1.8 1 0 0 1 1 1 1 Meleagrin/Cygnin family TPR_17 PF13431.6 KFX97595.1 - 0.16 12.4 0.0 0.46 11.0 0.0 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat Cep57_MT_bd PF06657.13 KFX97596.1 - 5.2e-30 103.7 0.1 5.2e-30 103.7 0.1 5.3 6 0 0 6 6 6 1 Centrosome microtubule-binding domain of Cep57 Cep57_CLD_2 PF14197.6 KFX97596.1 - 5.5e-08 32.8 7.9 5.5e-08 32.8 7.9 3.6 3 1 0 3 3 3 1 Centrosome localisation domain of PPC89 NmrA PF05368.13 KFX97596.1 - 2.7e-07 30.4 0.1 7.7e-07 28.9 0.0 1.8 2 0 0 2 2 2 1 NmrA-like family NRBF2 PF08961.10 KFX97596.1 - 0.0068 16.0 7.4 0.08 12.5 1.4 3.1 2 0 0 2 2 2 2 Nuclear receptor-binding factor 2, autophagy regulator HALZ PF02183.18 KFX97596.1 - 0.42 10.9 10.5 0.12 12.6 1.2 3.7 3 0 0 3 3 3 0 Homeobox associated leucine zipper TSC22 PF01166.18 KFX97596.1 - 0.45 10.9 3.2 17 5.8 0.2 3.1 2 0 0 2 2 2 0 TSC-22/dip/bun family SKG6 PF08693.10 KFX97597.1 - 1.2e-05 24.6 0.3 1.2e-05 24.6 0.3 1.8 2 0 0 2 2 2 1 Transmembrane alpha-helix domain DUF1180 PF06679.12 KFX97597.1 - 0.021 15.2 3.4 0.038 14.4 3.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) DUF2207 PF09972.9 KFX97597.1 - 0.19 10.4 0.0 0.23 10.2 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Gly-zipper_YMGG PF13441.6 KFX97597.1 - 0.23 11.2 18.7 0.18 11.6 14.8 2.3 2 0 0 2 2 2 0 YMGG-like Gly-zipper LPD23 PF18838.1 KFX97599.1 - 0.45 10.3 1.5 0.84 9.4 1.5 1.3 1 0 0 1 1 1 0 Large polyvalent protein associated domain 23 EB PF01683.18 KFX97599.1 - 7.2 7.0 71.9 0.67 10.3 14.1 8.1 2 2 3 5 5 5 0 EB module Aconitase_C PF00694.19 KFX97600.1 - 2.1e-39 134.9 0.0 3.5e-39 134.1 0.0 1.4 1 0 0 1 1 1 1 Aconitase C-terminal domain YCII PF03795.14 KFX97601.1 - 9.6e-05 22.7 0.0 0.00011 22.5 0.0 1.1 1 0 0 1 1 1 1 YCII-related domain SUV3_C PF12513.8 KFX97604.1 - 3.2e-19 68.6 0.1 3.2e-19 68.6 0.1 1.9 2 0 0 2 2 2 1 Mitochondrial degradasome RNA helicase subunit C terminal Helicase_C PF00271.31 KFX97604.1 - 3.1e-11 43.6 0.0 6.7e-11 42.5 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Suv3_C_1 PF18147.1 KFX97604.1 - 2.5e-06 27.3 0.2 5.9e-06 26.1 0.2 1.6 1 0 0 1 1 1 1 Suv3 C-terminal domain 1 Npa1 PF11707.8 KFX97605.1 - 3.1e-100 335.9 0.0 7.9e-100 334.5 0.0 1.7 2 0 0 2 2 2 1 Ribosome 60S biogenesis N-terminal NopRA1 PF16201.5 KFX97605.1 - 1.2e-54 184.9 1.0 8.5e-54 182.2 1.3 2.3 2 0 0 2 2 2 1 Nucleolar pre-ribosomal-associated protein 1 Longin PF13774.6 KFX97605.1 - 1.5e-28 98.7 0.0 3.8e-28 97.3 0.0 1.8 1 0 0 1 1 1 1 Regulated-SNARE-like domain Synaptobrevin PF00957.21 KFX97605.1 - 6.8e-15 54.6 0.1 1.6e-14 53.5 0.1 1.6 1 0 0 1 1 1 1 Synaptobrevin Arm PF00514.23 KFX97605.1 - 0.00056 19.8 0.4 0.0052 16.8 0.0 3.0 2 0 0 2 2 2 1 Armadillo/beta-catenin-like repeat Creb_binding PF09030.10 KFX97605.1 - 0.0038 17.9 0.3 0.015 16.0 0.0 2.1 2 0 0 2 2 2 1 Creb binding Hist_deacetyl PF00850.19 KFX97606.1 - 8.2e-77 258.7 0.0 1e-76 258.4 0.0 1.1 1 0 0 1 1 1 1 Histone deacetylase domain Ferritin_2 PF13668.6 KFX97607.1 - 2e-11 44.2 0.0 3.7e-11 43.4 0.0 1.4 1 0 0 1 1 1 1 Ferritin-like domain Mito_carr PF00153.27 KFX97608.1 - 7.5e-66 218.1 0.9 4.4e-23 81.0 0.0 3.9 3 1 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 KFX97608.1 - 0.052 12.7 0.2 3.1 6.9 0.0 3.1 4 0 0 4 4 4 0 Gammaproteobacterial serine protease Peptidase_C65 PF10275.9 KFX97634.1 - 2.5e-10 40.2 0.0 2.9e-10 40.0 0.0 1.1 1 0 0 1 1 1 1 Peptidase C65 Otubain DEAD PF00270.29 KFX97650.1 - 2.5e-46 157.7 1.0 4e-46 157.0 1.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KFX97650.1 - 1.6e-31 108.9 0.2 1.5e-30 105.8 0.0 2.5 2 1 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KFX97650.1 - 1.5e-06 28.3 0.0 2.4e-06 27.7 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_30 PF13604.6 KFX97650.1 - 0.00039 20.2 0.1 0.00081 19.2 0.1 1.4 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KFX97650.1 - 0.0013 19.1 0.6 0.0095 16.3 0.4 2.2 2 1 0 2 2 2 1 AAA domain IL17R_D_N PF16742.5 KFX97650.1 - 0.0081 16.2 0.0 0.02 14.9 0.0 1.6 1 0 0 1 1 1 1 N-terminus of interleukin 17 receptor D AAA_22 PF13401.6 KFX97650.1 - 0.014 15.6 0.4 0.072 13.4 0.4 2.1 1 1 0 1 1 1 0 AAA domain CMS1 PF14617.6 KFX97650.1 - 0.016 14.6 0.0 0.037 13.4 0.0 1.5 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit Flavi_DEAD PF07652.14 KFX97650.1 - 0.093 12.7 0.1 0.5 10.3 0.1 2.2 1 1 0 1 1 1 0 Flavivirus DEAD domain UvrD-helicase PF00580.21 KFX97650.1 - 0.12 11.9 0.1 0.17 11.4 0.1 1.4 1 1 0 1 1 1 0 UvrD/REP helicase N-terminal domain fragilysinNterm PF16376.5 KFX97650.1 - 0.12 12.1 0.0 0.29 10.9 0.0 1.6 1 0 0 1 1 1 0 N-terminal domain of fragilysin AAA_13 PF13166.6 KFX97651.1 - 0.047 12.3 10.6 0.072 11.7 10.6 1.3 1 0 0 1 1 1 0 AAA domain Gp58 PF07902.11 KFX97651.1 - 0.048 11.9 1.5 0.077 11.3 1.5 1.4 1 0 0 1 1 1 0 gp58-like protein Cor1 PF04803.12 KFX97651.1 - 0.089 13.0 6.5 1.5 9.0 1.1 2.7 1 1 1 2 2 2 0 Cor1/Xlr/Xmr conserved region Apolipoprotein PF01442.18 KFX97651.1 - 0.21 11.4 24.8 0.38 10.6 19.6 2.5 2 1 0 2 2 2 0 Apolipoprotein A1/A4/E domain Chalcone_2 PF16035.5 KFX97651.1 - 0.26 11.0 3.9 1.6 8.5 0.6 2.9 1 1 1 2 2 2 0 Chalcone isomerase like OmpH PF03938.14 KFX97651.1 - 0.35 11.2 23.2 0.092 13.1 7.5 2.7 2 1 1 3 3 3 0 Outer membrane protein (OmpH-like) DUF883 PF05957.13 KFX97651.1 - 1.6 9.4 17.2 1.6 9.4 0.8 4.1 3 1 1 4 4 4 0 Bacterial protein of unknown function (DUF883) RNase_J_C PF17770.1 KFX97651.1 - 2.2 9.4 4.5 19 6.4 0.2 3.5 2 1 1 3 3 3 0 Ribonuclease J C-terminal domain DUF4404 PF14357.6 KFX97651.1 - 4.1 8.1 13.2 2 9.1 3.3 3.5 2 1 1 3 3 3 0 Domain of unknown function (DUF4404) SKA2 PF16740.5 KFX97651.1 - 4.6 7.1 16.7 4.3 7.1 4.5 3.6 2 1 1 3 3 3 0 Spindle and kinetochore-associated protein 2 Prominin PF05478.11 KFX97651.1 - 6 4.7 7.1 0.77 7.6 1.1 1.9 1 1 0 2 2 2 0 Prominin DEAD PF00270.29 KFX97652.1 - 2.8e-09 37.0 0.0 2.8e-09 37.0 0.0 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase TerY_C PF15616.6 KFX97652.1 - 0.043 13.9 0.0 0.083 13.0 0.0 1.4 1 0 0 1 1 1 0 TerY-C metal binding domain FAM176 PF14851.6 KFX97653.1 - 0.0018 17.9 0.0 0.0024 17.5 0.0 1.1 1 0 0 1 1 1 1 FAM176 family ADH_N PF08240.12 KFX97657.1 - 5e-28 97.1 0.3 1e-27 96.1 0.1 1.7 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KFX97657.1 - 2.8e-14 53.2 1.9 6.7e-14 52.0 1.9 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 KFX97657.1 - 4.3e-07 29.6 0.7 0.0067 15.9 0.1 2.5 2 1 0 2 2 2 2 Glucose dehydrogenase C-terminus HI0933_like PF03486.14 KFX97657.1 - 0.00012 21.0 0.4 0.00018 20.4 0.4 1.2 1 0 0 1 1 1 1 HI0933-like protein AlaDh_PNT_C PF01262.21 KFX97657.1 - 0.00022 20.6 1.9 0.00029 20.2 1.2 1.6 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_2 PF00890.24 KFX97657.1 - 0.00061 19.0 3.1 0.00081 18.6 3.1 1.3 1 0 0 1 1 1 1 FAD binding domain 3HCDH_N PF02737.18 KFX97657.1 - 0.0015 18.4 0.4 0.0023 17.8 0.4 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_8 PF13450.6 KFX97657.1 - 0.002 18.3 2.1 0.0021 18.2 0.4 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain UDPG_MGDP_dh_N PF03721.14 KFX97657.1 - 0.0043 16.7 0.1 0.016 14.7 0.0 1.9 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain ADH_zinc_N_2 PF13602.6 KFX97657.1 - 0.0045 18.0 0.1 0.012 16.7 0.1 1.7 1 1 1 2 2 2 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 KFX97657.1 - 0.0063 15.9 0.0 0.011 15.1 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AdoHcyase_NAD PF00670.21 KFX97657.1 - 0.009 16.1 0.0 0.018 15.1 0.0 1.4 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Pyr_redox_2 PF07992.14 KFX97657.1 - 0.015 14.5 1.5 0.06 12.6 0.8 1.9 1 1 1 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KFX97657.1 - 0.063 12.5 0.6 0.11 11.8 0.6 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase XdhC_C PF13478.6 KFX97657.1 - 0.09 13.3 0.1 0.28 11.7 0.1 1.9 2 0 0 2 2 2 0 XdhC Rossmann domain ApbA PF02558.16 KFX97657.1 - 0.11 12.2 0.2 0.19 11.4 0.2 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Pyr_redox PF00070.27 KFX97657.1 - 0.12 12.9 0.1 0.31 11.6 0.1 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 KFX97657.1 - 0.33 10.0 3.0 0.43 9.6 3.0 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A DAO PF01266.24 KFX97657.1 - 1.5 8.3 6.0 1.2 8.7 2.3 2.1 1 1 1 2 2 2 0 FAD dependent oxidoreductase DFP PF04127.15 KFX97658.1 - 4.7e-13 49.4 0.0 9.5e-06 25.6 0.0 3.2 3 0 0 3 3 3 3 DNA / pantothenate metabolism flavoprotein ResIII PF04851.15 KFX97662.1 - 2.6e-22 79.6 0.0 5.1e-22 78.7 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 KFX97662.1 - 3.2e-19 69.3 0.5 1.2e-18 67.5 0.1 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 KFX97662.1 - 1.6e-15 57.3 0.0 5.3e-15 55.6 0.0 1.9 1 1 0 1 1 1 1 DEAD/DEAH box helicase SWI2_SNF2 PF18766.1 KFX97662.1 - 0.00015 21.5 0.0 0.00026 20.7 0.0 1.3 1 0 0 1 1 1 1 SWI2/SNF2 ATPase AAA_22 PF13401.6 KFX97662.1 - 0.0053 17.0 0.0 0.016 15.4 0.0 1.8 1 0 0 1 1 1 1 AAA domain Cation_ATPase_C PF00689.21 KFX97663.1 - 6.5e-32 110.7 2.6 6.5e-32 110.7 2.6 2.2 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 KFX97663.1 - 4.3e-31 107.8 24.0 3.2e-26 92.0 0.4 3.9 5 0 0 5 5 5 2 E1-E2 ATPase Cation_ATPase PF13246.6 KFX97663.1 - 6e-21 74.3 0.0 1.4e-20 73.1 0.0 1.7 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 KFX97663.1 - 2e-19 70.7 3.0 1e-17 65.1 3.0 2.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 KFX97663.1 - 1.7e-12 46.8 0.0 5e-12 45.3 0.0 1.8 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 KFX97663.1 - 1.1e-05 25.3 0.4 0.0021 17.9 0.4 2.4 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase CoatB PF10389.9 KFX97663.1 - 3.4 7.6 7.0 0.71 9.8 2.4 2.4 2 0 0 2 2 2 0 Bacteriophage coat protein B BAH PF01426.18 KFX97664.1 - 5.1e-06 26.3 0.0 1.2e-05 25.1 0.0 1.8 1 1 0 1 1 1 1 BAH domain GFO_IDH_MocA PF01408.22 KFX97664.1 - 0.19 12.6 0.0 14 6.5 0.0 2.4 2 0 0 2 2 2 0 Oxidoreductase family, NAD-binding Rossmann fold zf-RING-like PF08746.11 KFX97664.1 - 0.41 11.0 4.6 1 9.7 3.7 2.1 1 1 1 2 2 2 0 RING-like domain PHD PF00628.29 KFX97664.1 - 2.1 8.3 10.9 0.4 10.6 5.0 2.4 2 0 0 2 2 2 0 PHD-finger ATP-synt PF00231.19 KFX97665.1 - 9.8e-78 261.7 7.2 1.2e-77 261.4 7.2 1.0 1 0 0 1 1 1 1 ATP synthase Topoisom_I PF01028.20 KFX97666.1 - 1.4e-96 322.2 4.9 1.4e-96 322.2 4.9 1.9 3 0 0 3 3 3 1 Eukaryotic DNA topoisomerase I, catalytic core Topoisom_I_N PF02919.15 KFX97666.1 - 4.8e-95 317.1 1.2 4.8e-95 317.1 1.2 4.1 4 1 1 5 5 5 1 Eukaryotic DNA topoisomerase I, DNA binding fragment Topo_C_assoc PF14370.6 KFX97666.1 - 2.6e-32 110.6 0.4 1.1e-31 108.6 0.4 2.2 1 0 0 1 1 1 1 C-terminal topoisomerase domain Rab_bind PF16704.5 KFX97666.1 - 0.0059 16.6 1.2 0.015 15.3 0.1 2.3 3 0 0 3 3 3 1 Rab binding domain Csm1_N PF18504.1 KFX97666.1 - 0.007 16.7 2.8 0.007 16.7 2.8 3.4 3 1 0 3 3 3 1 Csm1 N-terminal domain Epimerase PF01370.21 KFX97667.1 - 2.1e-20 73.3 0.0 3.1e-20 72.7 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 KFX97667.1 - 1.2e-08 34.5 0.1 1.5e-08 34.1 0.1 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain GDP_Man_Dehyd PF16363.5 KFX97667.1 - 7.8e-08 32.1 0.0 1e-07 31.7 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 KFX97667.1 - 4.1e-06 26.0 0.0 6.4e-06 25.4 0.0 1.3 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 KFX97667.1 - 0.00021 21.2 0.0 0.00033 20.6 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding adh_short PF00106.25 KFX97667.1 - 0.0058 16.1 0.0 0.023 14.2 0.0 1.9 1 1 1 2 2 2 1 short chain dehydrogenase Ldh_1_N PF00056.23 KFX97667.1 - 0.018 15.1 0.0 0.076 13.1 0.0 1.9 2 0 0 2 2 2 0 lactate/malate dehydrogenase, NAD binding domain KR PF08659.10 KFX97667.1 - 0.027 14.4 0.0 0.044 13.7 0.0 1.3 1 0 0 1 1 1 0 KR domain Sacchrp_dh_NADP PF03435.18 KFX97667.1 - 0.029 14.6 0.0 0.052 13.8 0.0 1.6 1 1 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain UCH PF00443.29 KFX97669.1 - 7.8e-47 159.9 0.0 1.2e-46 159.3 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KFX97669.1 - 7.7e-10 38.9 0.0 0.0002 21.1 0.0 2.3 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase zf-C3HC4 PF00097.25 KFX97670.1 - 4.6e-07 29.6 8.7 7.9e-07 28.9 8.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KFX97670.1 - 6.9e-06 25.8 6.4 4.9e-05 23.1 3.5 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KFX97670.1 - 1.1e-05 25.3 5.4 1.1e-05 25.3 5.4 1.7 1 1 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 KFX97670.1 - 1.9e-05 24.4 6.1 3.5e-05 23.6 6.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 KFX97670.1 - 2.4e-05 24.4 7.6 4.8e-05 23.4 7.6 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.6 KFX97670.1 - 2.6e-05 24.5 8.7 5.8e-05 23.3 8.7 1.6 1 1 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 KFX97670.1 - 0.00012 22.0 6.4 0.00023 21.0 6.4 1.4 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 KFX97670.1 - 0.0073 16.1 8.4 0.083 12.8 8.2 2.5 1 1 1 2 2 2 2 Prokaryotic RING finger family 4 zf-rbx1 PF12678.7 KFX97670.1 - 1.2 9.4 6.5 3.4 8.0 6.5 1.7 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-RING_10 PF16685.5 KFX97670.1 - 1.5 9.0 4.3 3.4 7.9 4.3 1.6 1 0 0 1 1 1 0 zinc RING finger of MSL2 4HBT_2 PF13279.6 KFX97671.1 - 2e-07 31.5 0.0 3.2e-07 30.9 0.0 1.3 1 0 0 1 1 1 1 Thioesterase-like superfamily CMAS PF02353.20 KFX97672.1 - 2.4e-63 214.0 0.2 3e-63 213.7 0.2 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_11 PF08241.12 KFX97672.1 - 2e-10 41.2 0.0 4.4e-10 40.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KFX97672.1 - 1.3e-08 34.9 0.0 2e-08 34.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KFX97672.1 - 1.7e-08 35.0 0.0 4e-08 33.9 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KFX97672.1 - 0.00021 21.9 0.0 0.00039 21.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain DOT1 PF08123.13 KFX97672.1 - 0.0025 17.4 0.0 0.0046 16.5 0.0 1.3 1 0 0 1 1 1 1 Histone methylation protein DOT1 MTS PF05175.14 KFX97672.1 - 0.0025 17.4 0.0 0.0054 16.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain PCMT PF01135.19 KFX97672.1 - 0.014 15.2 0.0 0.022 14.5 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_31 PF13847.6 KFX97672.1 - 0.053 13.3 0.0 0.084 12.7 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_32 PF13679.6 KFX97672.1 - 0.057 13.4 0.0 0.091 12.7 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain 2OG-FeII_Oxy PF03171.20 KFX97673.1 - 7.8e-20 71.3 0.0 4.8e-19 68.7 0.0 2.2 2 1 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.6 KFX97673.1 - 5.5e-10 40.0 0.0 8.1e-10 39.5 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal Dioxygenase_C PF00775.21 KFX97675.1 - 1.8e-09 37.3 0.1 2.8e-09 36.7 0.1 1.3 1 0 0 1 1 1 1 Dioxygenase MFS_1 PF07690.16 KFX97676.1 - 9.2e-45 153.1 44.6 1.7e-44 152.2 38.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KFX97676.1 - 5.2e-06 25.6 13.8 5.2e-06 25.6 13.8 2.7 3 0 0 3 3 3 1 Sugar (and other) transporter OATP PF03137.20 KFX97676.1 - 0.11 10.7 4.6 0.035 12.4 1.7 1.6 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family CFEM PF05730.11 KFX97677.1 - 1.6e-10 40.9 13.9 2.5e-10 40.3 13.9 1.3 1 0 0 1 1 1 1 CFEM domain Macoilin PF09726.9 KFX97677.1 - 6.6 5.2 4.4 6.8 5.1 4.4 1.1 1 0 0 1 1 1 0 Macoilin family p450 PF00067.22 KFX97679.1 - 5.8e-51 173.7 0.0 8.1e-51 173.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Cyclase PF04199.13 KFX97680.1 - 2.3e-10 40.9 0.0 6.2e-10 39.5 0.0 1.8 1 1 0 1 1 1 1 Putative cyclase Methyltransf_31 PF13847.6 KFX97685.1 - 5e-26 91.3 0.0 8e-26 90.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KFX97685.1 - 9.4e-19 67.9 0.0 1.8e-18 67.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KFX97685.1 - 6e-17 62.1 0.0 1.2e-16 61.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KFX97685.1 - 4.9e-14 52.2 0.0 7.7e-14 51.6 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 KFX97685.1 - 1.3e-10 41.8 0.0 2.2e-10 41.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KFX97685.1 - 5.5e-10 39.3 0.0 9.7e-10 38.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 KFX97685.1 - 1.3e-07 31.4 0.2 2.9e-07 30.2 0.1 1.5 2 0 0 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) PCMT PF01135.19 KFX97685.1 - 6.7e-07 29.3 0.0 9.7e-07 28.7 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) DOT1 PF08123.13 KFX97685.1 - 6.3e-05 22.6 0.0 0.0001 21.9 0.0 1.3 1 0 0 1 1 1 1 Histone methylation protein DOT1 MTS PF05175.14 KFX97685.1 - 0.00039 20.0 0.0 0.00066 19.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain CMAS PF02353.20 KFX97685.1 - 0.00047 19.5 0.0 0.00072 18.9 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_4 PF02390.17 KFX97685.1 - 0.023 14.2 0.0 0.042 13.3 0.0 1.4 1 0 0 1 1 1 0 Putative methyltransferase UPF0020 PF01170.18 KFX97685.1 - 0.041 13.6 0.0 0.072 12.8 0.0 1.3 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 Fe_hyd_lg_C PF02906.14 KFX97685.1 - 0.058 13.0 0.0 0.1 12.3 0.0 1.3 1 0 0 1 1 1 0 Iron only hydrogenase large subunit, C-terminal domain Methyltransf_9 PF08003.11 KFX97685.1 - 0.2 10.5 0.0 12 4.7 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1698) Zn_clus PF00172.18 KFX97686.1 - 9.3e-05 22.5 13.7 0.00015 21.8 13.7 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KFX97686.1 - 0.012 14.7 0.0 0.02 13.9 0.0 1.3 1 0 0 1 1 1 0 Fungal specific transcription factor domain Sulfotransfer_4 PF17784.1 KFX97687.1 - 0.001 19.0 0.0 0.44 10.3 0.0 2.5 2 1 1 3 3 3 2 Sulfotransferase domain RTA1 PF04479.13 KFX97688.1 - 3.8e-75 252.0 7.8 6.1e-75 251.4 7.8 1.3 1 0 0 1 1 1 1 RTA1 like protein PhrC_PhrF PF11131.8 KFX97688.1 - 8.8 6.0 7.4 1.6 8.3 0.4 3.0 3 0 0 3 3 3 0 Rap-phr extracellular signalling AstE_AspA PF04952.14 KFX97689.1 - 9.5e-22 77.4 0.0 5e-13 48.8 0.0 2.9 2 1 1 3 3 3 2 Succinylglutamate desuccinylase / Aspartoacylase family MFS_1 PF07690.16 KFX97690.1 - 8.1e-35 120.4 31.6 1.2e-34 119.8 31.6 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_4 PF06779.14 KFX97690.1 - 7.7e-09 35.3 1.9 7.7e-09 35.3 1.9 1.7 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB Fungal_trans_2 PF11951.8 KFX97691.1 - 0.00014 20.8 0.7 0.02 13.7 0.0 2.4 3 0 0 3 3 3 2 Fungal specific transcription factor domain Methyltransf_11 PF08241.12 KFX97692.1 - 9.3e-21 74.3 0.0 3.6e-20 72.4 0.1 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 KFX97692.1 - 2e-19 70.1 0.1 5.9e-19 68.6 0.1 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 KFX97692.1 - 6.1e-16 58.6 0.0 7.8e-16 58.2 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KFX97692.1 - 2.2e-14 53.6 0.0 4.5e-14 52.6 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 KFX97692.1 - 3.1e-12 46.4 0.0 4.5e-12 45.8 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_12 PF08242.12 KFX97692.1 - 1.1e-11 45.3 0.0 1.8e-11 44.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KFX97692.1 - 1.2e-09 37.8 0.0 3.3e-08 33.2 0.0 2.0 1 1 1 2 2 2 1 ubiE/COQ5 methyltransferase family PCMT PF01135.19 KFX97692.1 - 8.4e-08 32.2 0.0 1.2e-07 31.7 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_18 PF12847.7 KFX97692.1 - 1.3e-07 31.6 0.1 2.4e-07 30.8 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KFX97692.1 - 5.7e-07 29.2 0.0 8.9e-07 28.6 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_9 PF08003.11 KFX97692.1 - 1.3e-05 24.3 0.0 1.9e-05 23.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Methyltransf_32 PF13679.6 KFX97692.1 - 1.8e-05 24.8 0.0 2.4e-05 24.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain UPF0020 PF01170.18 KFX97692.1 - 4.6e-05 23.2 0.0 0.00013 21.7 0.0 1.6 1 1 0 1 1 1 1 Putative RNA methylase family UPF0020 PrmA PF06325.13 KFX97692.1 - 8.7e-05 22.0 0.1 0.00013 21.5 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MetW PF07021.12 KFX97692.1 - 0.0001 22.0 0.0 0.00016 21.3 0.0 1.2 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW TrmK PF04816.12 KFX97692.1 - 0.00011 21.8 0.1 0.00016 21.3 0.1 1.2 1 0 0 1 1 1 1 tRNA (adenine(22)-N(1))-methyltransferase Methyltransf_15 PF09445.10 KFX97692.1 - 0.00014 21.5 0.0 0.0002 21.0 0.0 1.2 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase TPMT PF05724.11 KFX97692.1 - 0.0003 20.5 0.0 0.00048 19.8 0.0 1.4 1 1 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) GCD14 PF08704.10 KFX97692.1 - 0.0018 18.0 0.1 0.0035 17.1 0.1 1.4 1 1 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit TehB PF03848.14 KFX97692.1 - 0.0036 16.7 0.0 0.0054 16.2 0.0 1.2 1 0 0 1 1 1 1 Tellurite resistance protein TehB NodS PF05401.11 KFX97692.1 - 0.014 15.0 0.0 0.02 14.5 0.0 1.2 1 0 0 1 1 1 0 Nodulation protein S (NodS) Methyltransf_24 PF13578.6 KFX97692.1 - 0.015 16.3 0.1 0.031 15.3 0.1 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_4 PF02390.17 KFX97692.1 - 0.074 12.5 0.0 0.89 9.0 0.0 2.1 2 0 0 2 2 2 0 Putative methyltransferase Methyltransf_8 PF05148.15 KFX97692.1 - 0.093 12.6 0.0 0.94 9.3 0.0 2.0 1 1 0 1 1 1 0 Hypothetical methyltransferase SYF2 PF08231.12 KFX97698.1 - 4.3e-55 186.5 14.6 4.3e-55 186.5 14.6 2.0 2 1 0 2 2 2 1 SYF2 splicing factor ARD PF03079.14 KFX97698.1 - 0.018 15.2 1.0 0.018 15.2 1.0 2.9 2 1 0 3 3 3 0 ARD/ARD' family Epimerase PF01370.21 KFX97699.1 - 5.1e-06 26.1 0.0 9.4e-06 25.3 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 KFX97699.1 - 1.1e-05 25.4 0.0 5e-05 23.3 0.0 2.2 1 1 0 1 1 1 1 NAD(P)H-binding 3Beta_HSD PF01073.19 KFX97699.1 - 0.00061 18.9 0.0 0.0012 17.9 0.0 1.5 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 KFX97699.1 - 0.007 15.6 0.0 0.051 12.7 0.0 2.3 2 1 0 2 2 2 1 Male sterility protein RmlD_sub_bind PF04321.17 KFX97699.1 - 0.029 13.5 0.0 0.23 10.5 0.0 2.2 2 1 0 2 2 2 0 RmlD substrate binding domain GDP_Man_Dehyd PF16363.5 KFX97699.1 - 0.071 12.5 0.0 0.15 11.5 0.0 1.5 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase adh_short PF00106.25 KFX97699.1 - 0.12 11.8 0.0 0.26 10.7 0.0 1.6 1 0 0 1 1 1 0 short chain dehydrogenase DUF3667 PF12412.8 KFX97699.1 - 0.15 11.5 0.0 0.31 10.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3667) YEATS PF03366.16 KFX97700.1 - 4.8e-29 100.1 0.1 8.3e-29 99.4 0.1 1.4 1 0 0 1 1 1 1 YEATS family Med30 PF11315.8 KFX97700.1 - 0.05 13.8 0.1 0.081 13.1 0.1 1.3 1 0 0 1 1 1 0 Mediator complex subunit 30 TruB_C PF09142.11 KFX97700.1 - 0.12 12.2 0.0 0.27 11.0 0.0 1.6 1 0 0 1 1 1 0 tRNA Pseudouridine synthase II, C terminal GCV_T_C PF08669.11 KFX97701.1 - 0.14 12.1 0.0 0.41 10.6 0.0 1.7 1 0 0 1 1 1 0 Glycine cleavage T-protein C-terminal barrel domain DEAD PF00270.29 KFX97702.1 - 1e-32 113.3 0.0 1.6e-32 112.7 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KFX97702.1 - 1.1e-18 67.5 0.0 6.7e-17 61.8 0.0 3.4 4 0 0 4 4 4 1 Helicase conserved C-terminal domain ResIII PF04851.15 KFX97702.1 - 3e-05 24.1 0.0 7.8e-05 22.7 0.0 1.7 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit Methyltransf_31 PF13847.6 KFX97703.1 - 3.8e-30 104.7 0.0 5.3e-30 104.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KFX97703.1 - 7.3e-25 87.5 0.1 1.6e-24 86.4 0.1 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KFX97703.1 - 1.2e-24 86.7 0.0 2.2e-24 85.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KFX97703.1 - 5.5e-20 71.8 0.0 8.3e-20 71.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KFX97703.1 - 2.6e-18 66.2 0.0 4.6e-18 65.4 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 KFX97703.1 - 7.6e-18 65.1 0.0 1.3e-17 64.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MetW PF07021.12 KFX97703.1 - 9.5e-09 35.1 0.0 1.4e-08 34.6 0.0 1.2 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW MTS PF05175.14 KFX97703.1 - 8.3e-07 28.7 0.0 1.3e-06 28.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain PCMT PF01135.19 KFX97703.1 - 2.3e-06 27.5 0.0 3.2e-06 27.1 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_2 PF00891.18 KFX97703.1 - 8.5e-06 25.2 0.0 1.1e-05 24.9 0.0 1.1 1 0 0 1 1 1 1 O-methyltransferase domain CMAS PF02353.20 KFX97703.1 - 0.00019 20.8 0.0 0.00023 20.6 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_4 PF02390.17 KFX97703.1 - 0.00024 20.6 0.0 0.00037 20.0 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase PrmA PF06325.13 KFX97703.1 - 0.00064 19.2 0.0 0.00087 18.8 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) FtsJ PF01728.19 KFX97703.1 - 0.00098 19.3 0.0 0.0017 18.5 0.0 1.4 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_29 PF03141.16 KFX97703.1 - 0.0012 17.5 0.0 0.0015 17.2 0.0 1.2 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_9 PF08003.11 KFX97703.1 - 0.0033 16.4 0.0 0.0068 15.4 0.0 1.4 2 0 0 2 2 2 1 Protein of unknown function (DUF1698) NodS PF05401.11 KFX97703.1 - 0.0062 16.2 0.0 0.0089 15.7 0.0 1.2 1 0 0 1 1 1 1 Nodulation protein S (NodS) GCD14 PF08704.10 KFX97703.1 - 0.011 15.4 0.0 0.015 15.0 0.0 1.2 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit DREV PF05219.12 KFX97703.1 - 0.036 13.1 0.0 0.057 12.5 0.0 1.3 1 0 0 1 1 1 0 DREV methyltransferase Methyltransf_18 PF12847.7 KFX97703.1 - 0.041 13.8 0.0 0.078 12.9 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_32 PF13679.6 KFX97703.1 - 0.053 13.5 0.0 0.073 13.1 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain p450 PF00067.22 KFX97704.1 - 2.2e-61 208.0 0.0 3.2e-61 207.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 CBFD_NFYB_HMF PF00808.23 KFX97704.1 - 7e-13 48.7 3.2 2.6e-12 46.8 1.4 2.6 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 KFX97704.1 - 0.00023 21.5 0.3 0.00023 21.5 0.3 2.2 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 DUF3851 PF12962.7 KFX97704.1 - 0.12 12.7 0.0 0.25 11.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3851) WXG100 PF06013.12 KFX97705.1 - 0.0033 17.6 4.4 0.95 9.7 0.1 4.0 3 1 0 4 4 4 1 Proteins of 100 residues with WXG CASP_C PF08172.12 KFX97705.1 - 0.0099 15.2 2.5 0.0099 15.2 2.5 1.6 2 0 0 2 2 2 1 CASP C terminal Fib_alpha PF08702.10 KFX97705.1 - 0.067 13.4 5.1 4.6 7.4 0.0 3.3 2 2 0 3 3 3 0 Fibrinogen alpha/beta chain family DASH_Dad2 PF08654.10 KFX97705.1 - 0.095 13.1 7.7 6.3 7.3 0.3 3.4 2 1 0 3 3 3 0 DASH complex subunit Dad2 BCDHK_Adom3 PF10436.9 KFX97705.1 - 0.12 12.2 0.5 0.31 10.9 0.3 1.9 1 1 0 1 1 1 0 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase DASH_Dam1 PF08653.10 KFX97705.1 - 0.14 12.0 0.6 18 5.3 0.2 3.4 3 0 0 3 3 3 0 DASH complex subunit Dam1 CENP-F_leu_zip PF10473.9 KFX97705.1 - 0.2 11.7 18.0 3.1 7.8 10.8 3.1 3 0 0 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 APC_N_CC PF16689.5 KFX97705.1 - 0.26 11.4 5.4 5 7.3 1.7 2.6 2 0 0 2 2 2 0 Coiled-coil N-terminus of APC, dimerisation domain BLOC1_2 PF10046.9 KFX97705.1 - 0.26 11.6 9.0 0.35 11.2 1.2 3.5 2 2 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DivIVA PF05103.13 KFX97705.1 - 0.34 11.0 9.6 0.13 12.4 6.1 2.1 2 1 0 2 2 2 0 DivIVA protein ATG16 PF08614.11 KFX97705.1 - 0.37 11.0 14.1 3.1 8.0 0.2 2.9 3 0 0 3 3 3 0 Autophagy protein 16 (ATG16) DUF2031 PF09592.10 KFX97705.1 - 0.45 10.0 7.3 3 7.3 0.6 2.5 2 1 0 3 3 3 0 Protein of unknown function (DUF2031) YtxH PF12732.7 KFX97705.1 - 0.88 10.1 9.0 6.7e+02 0.9 9.0 3.7 1 1 0 1 1 1 0 YtxH-like protein SpoVR PF04293.13 KFX97705.1 - 1.2 7.7 5.7 0.69 8.5 1.7 2.1 1 1 0 2 2 2 0 SpoVR like protein HALZ PF02183.18 KFX97705.1 - 1.3 9.3 12.9 0.11 12.7 4.9 2.8 3 0 0 3 3 3 0 Homeobox associated leucine zipper DUF1664 PF07889.12 KFX97705.1 - 1.5 8.9 7.7 5.2 7.1 0.5 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) Occludin_ELL PF07303.13 KFX97705.1 - 1.8 9.3 7.2 8.2 7.2 0.6 3.5 3 1 0 3 3 3 0 Occludin homology domain DUF4407 PF14362.6 KFX97705.1 - 2 7.7 7.1 12 5.1 3.4 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) EMP24_GP25L PF01105.24 KFX97705.1 - 2 8.3 10.3 0.41 10.6 0.1 3.0 1 1 2 3 3 3 0 emp24/gp25L/p24 family/GOLD Spc24 PF08286.11 KFX97705.1 - 3.2 8.1 10.1 0.47 10.7 1.0 3.2 2 1 0 3 3 3 0 Spc24 subunit of Ndc80 H-kinase_dim PF02895.14 KFX97705.1 - 3.4 8.1 9.0 18 5.8 6.2 3.0 2 1 0 2 2 2 0 Signal transducing histidine kinase, homodimeric domain YabA PF06156.13 KFX97705.1 - 4.2 8.1 11.0 0.93 10.2 1.5 3.3 2 1 1 3 3 3 0 Initiation control protein YabA Prefoldin PF02996.17 KFX97705.1 - 8.1 6.4 14.7 3.1 7.7 4.1 4.1 3 2 2 5 5 5 0 Prefoldin subunit DivIC PF04977.15 KFX97705.1 - 8.8 6.2 13.1 1.5 8.7 4.0 3.3 3 2 1 4 4 4 0 Septum formation initiator CTP_synth_N PF06418.14 KFX97706.1 - 6.7e-125 415.7 0.2 8.5e-125 415.4 0.2 1.1 1 0 0 1 1 1 1 CTP synthase N-terminus GATase PF00117.28 KFX97706.1 - 1.8e-55 187.7 0.0 3e-55 186.9 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 KFX97706.1 - 8.9e-07 28.9 0.1 5.6e-06 26.3 0.1 2.2 1 1 0 1 1 1 1 Peptidase C26 Lyase_1 PF00206.20 KFX97707.1 - 1.1e-20 74.3 0.1 1.8e-20 73.6 0.1 1.4 1 0 0 1 1 1 1 Lyase ADSL_C PF10397.9 KFX97707.1 - 4.7e-14 52.7 0.0 1.9e-13 50.7 0.0 2.1 1 0 0 1 1 1 1 Adenylosuccinate lyase C-terminus DUF3328 PF11807.8 KFX97708.1 - 2.2e-26 93.0 0.5 2.7e-26 92.7 0.5 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) AIM3 PF17096.5 KFX97710.1 - 0.074 14.0 3.0 0.12 13.3 3.0 1.3 1 0 0 1 1 1 0 Altered inheritance of mitochondria protein 3 Reprolysin_3 PF13582.6 KFX97712.1 - 0.0024 18.4 0.1 0.0055 17.2 0.1 1.6 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.6 KFX97712.1 - 0.0058 16.8 0.2 0.0082 16.3 0.2 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_2 PF13574.6 KFX97712.1 - 0.097 12.6 0.1 0.16 11.8 0.1 1.3 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like adh_short PF00106.25 KFX97713.1 - 1.9e-31 109.1 0.0 2.6e-31 108.6 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KFX97713.1 - 3.6e-23 82.4 0.0 1.4e-22 80.5 0.0 1.7 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KFX97713.1 - 2.5e-08 34.1 0.0 3.9e-08 33.4 0.0 1.2 1 0 0 1 1 1 1 KR domain RtcR PF06956.11 KFX97713.1 - 0.0052 16.2 0.0 0.01 15.3 0.0 1.4 1 0 0 1 1 1 1 Regulator of RNA terminal phosphate cyclase ATP-grasp_5 PF13549.6 KFX97713.1 - 0.039 13.4 0.1 0.071 12.6 0.1 1.4 1 0 0 1 1 1 0 ATP-grasp domain MFS_1 PF07690.16 KFX97714.1 - 2.2e-23 82.8 10.6 2.6e-23 82.5 10.6 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Gln-synt_N PF03951.19 KFX97714.1 - 0.077 12.7 0.0 0.29 10.9 0.0 1.9 2 0 0 2 2 2 0 Glutamine synthetase, beta-Grasp domain CDC45 PF02724.14 KFX97715.1 - 1.7e-227 756.8 0.5 1e-226 754.2 0.5 2.7 1 1 0 1 1 1 1 CDC45-like protein Thioredoxin_12 PF18400.1 KFX97715.1 - 0.016 15.1 0.0 0.028 14.3 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin-like domain SAPS PF04499.15 KFX97715.1 - 0.42 9.3 4.5 0.43 9.3 0.4 2.0 2 0 0 2 2 2 0 SIT4 phosphatase-associated protein BUD22 PF09073.10 KFX97715.1 - 1.3 8.3 36.5 0.15 11.3 13.8 2.4 3 0 0 3 3 3 0 BUD22 CSRNP_N PF16019.5 KFX97715.1 - 7.6 6.4 9.2 0.27 11.1 2.6 1.9 2 0 0 2 2 2 0 Cysteine/serine-rich nuclear protein N-terminus Sugar_tr PF00083.24 KFX97718.1 - 9.9e-107 357.6 25.8 1.2e-106 357.4 25.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KFX97718.1 - 1.7e-22 79.8 32.1 6.6e-15 54.9 9.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Crystall PF00030.19 KFX97720.1 - 9.4e-05 22.5 0.1 0.0003 20.9 0.0 1.8 2 0 0 2 2 2 1 Beta/Gamma crystallin Crystall_3 PF08964.10 KFX97720.1 - 0.044 13.9 0.2 0.14 12.3 0.0 1.9 2 0 0 2 2 2 0 Beta/Gamma crystallin Crystall PF00030.19 KFX97721.1 - 0.06 13.5 0.0 0.073 13.3 0.0 1.1 1 0 0 1 1 1 0 Beta/Gamma crystallin DUF1682 PF07946.14 KFX97722.1 - 3.5e-106 355.1 0.0 4e-106 354.9 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1682) Methyltransf_23 PF13489.6 KFX97723.1 - 1.8e-12 47.4 0.0 2.8e-12 46.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KFX97723.1 - 8.9e-07 29.5 0.0 4.2e-06 27.4 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KFX97723.1 - 0.00019 22.0 0.0 0.00038 21.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KFX97723.1 - 0.00043 21.0 0.1 0.0068 17.1 0.1 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KFX97723.1 - 0.0055 16.5 0.0 0.27 11.0 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_2 PF00891.18 KFX97723.1 - 0.029 13.7 0.0 0.049 12.9 0.0 1.4 1 0 0 1 1 1 0 O-methyltransferase domain MTS PF05175.14 KFX97723.1 - 0.044 13.3 0.0 0.11 12.1 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase small domain FAD_binding_3 PF01494.19 KFX97724.1 - 2.8e-19 69.6 1.8 6.1e-13 48.7 0.2 2.3 2 1 0 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.14 KFX97724.1 - 1.7e-06 27.5 0.2 0.0017 17.6 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 KFX97724.1 - 1.5e-05 24.5 0.1 0.00019 20.9 0.0 2.3 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 KFX97724.1 - 0.00026 21.2 0.1 0.00086 19.5 0.0 1.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 KFX97724.1 - 0.00092 18.0 0.1 0.65 8.6 0.0 2.2 2 0 0 2 2 2 2 HI0933-like protein FAD_binding_2 PF00890.24 KFX97724.1 - 0.0026 16.9 1.4 0.0092 15.1 0.4 2.1 2 0 0 2 2 2 1 FAD binding domain DAO PF01266.24 KFX97724.1 - 0.003 17.2 0.1 0.35 10.4 0.1 2.3 1 1 1 2 2 2 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 KFX97724.1 - 0.0037 17.8 0.1 2.1 8.9 0.0 2.6 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KFX97724.1 - 0.024 13.9 0.0 3.8 6.7 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KFX97724.1 - 0.042 13.8 0.1 2.4 8.1 0.0 2.5 2 0 0 2 2 2 0 FAD-NAD(P)-binding NAD_binding_4 PF07993.12 KFX97726.1 - 3.2e-12 46.2 0.0 2.1e-06 27.1 0.0 2.1 2 0 0 2 2 2 2 Male sterility protein Epimerase PF01370.21 KFX97726.1 - 2.4e-11 43.6 0.0 9.7e-11 41.6 0.0 1.9 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 KFX97726.1 - 5.4e-07 29.7 0.0 1.8e-06 28.0 0.0 1.9 2 1 0 2 2 2 1 NAD(P)H-binding 3Beta_HSD PF01073.19 KFX97726.1 - 4.2e-06 26.0 0.0 6.1e-06 25.4 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 KFX97726.1 - 4.1e-05 23.2 0.0 6.1e-05 22.6 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 KFX97726.1 - 0.045 12.8 0.0 0.071 12.2 0.0 1.3 1 0 0 1 1 1 0 RmlD substrate binding domain ADK PF00406.22 KFX97727.1 - 9.9e-59 197.8 0.1 1.3e-58 197.4 0.1 1.1 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 KFX97727.1 - 6e-21 75.3 0.3 1e-20 74.6 0.3 1.5 1 1 0 1 1 1 1 AAA domain ADK_lid PF05191.14 KFX97727.1 - 7.2e-18 64.3 0.0 1.8e-17 63.0 0.0 1.7 2 0 0 2 2 2 1 Adenylate kinase, active site lid AAA_18 PF13238.6 KFX97727.1 - 8.1e-06 26.4 0.0 1.4e-05 25.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 KFX97727.1 - 0.007 16.5 0.0 0.012 15.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain DASH_Spc19 PF08287.11 KFX97727.1 - 0.081 12.8 1.0 11 5.9 0.1 2.4 1 1 1 2 2 2 0 Spc19 Mg_chelatase PF01078.21 KFX97727.1 - 0.092 12.1 0.1 0.16 11.4 0.1 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI MitMem_reg PF13012.6 KFX97728.1 - 1.3e-36 125.5 0.2 2.8e-36 124.3 0.2 1.6 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function Cyclin PF08613.11 KFX97728.1 - 2.5e-30 106.0 0.1 7.5e-30 104.4 0.0 1.9 2 0 0 2 2 2 1 Cyclin JAB PF01398.21 KFX97728.1 - 3.7e-30 104.3 0.0 8.7e-30 103.1 0.0 1.6 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Cyclin_N PF00134.23 KFX97728.1 - 0.00075 19.2 0.0 0.0014 18.4 0.0 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain tRNA_bind_2 PF13725.6 KFX97728.1 - 0.012 15.3 6.5 0.019 14.7 6.5 1.2 1 0 0 1 1 1 0 Possible tRNA binding domain Vfa1 PF08432.10 KFX97728.1 - 0.29 11.4 6.0 0.67 10.3 6.0 1.5 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Connexin PF00029.19 KFX97728.1 - 0.56 9.9 1.0 1.2 8.9 1.0 1.4 1 0 0 1 1 1 0 Connexin Lipase_3 PF01764.25 KFX97729.1 - 1.4e-36 125.4 0.0 2.7e-36 124.5 0.0 1.5 1 0 0 1 1 1 1 Lipase (class 3) Lipase3_N PF03893.16 KFX97729.1 - 7.3e-07 29.1 0.3 1.9e-06 27.8 0.3 1.6 1 0 0 1 1 1 1 Lipase 3 N-terminal region DUF2974 PF11187.8 KFX97729.1 - 6e-05 22.7 0.7 0.00027 20.6 0.7 2.1 1 1 0 1 1 1 1 Protein of unknown function (DUF2974) Abhydrolase_6 PF12697.7 KFX97729.1 - 9.7e-05 23.1 0.5 0.00017 22.3 0.5 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_8 PF06259.12 KFX97729.1 - 0.00088 19.0 1.5 0.001 18.8 0.2 1.9 2 0 0 2 2 2 1 Alpha/beta hydrolase Hydrolase_4 PF12146.8 KFX97729.1 - 0.00096 18.5 0.1 0.0027 17.0 0.0 1.7 2 0 0 2 2 2 1 Serine aminopeptidase, S33 PGAP1 PF07819.13 KFX97729.1 - 0.0084 15.9 0.0 0.015 15.1 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein DUF676 PF05057.14 KFX97729.1 - 0.0092 15.5 0.0 0.014 14.9 0.0 1.2 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Cutinase PF01083.22 KFX97729.1 - 0.022 14.7 0.0 0.066 13.2 0.0 1.8 1 0 0 1 1 1 0 Cutinase Abhydrolase_5 PF12695.7 KFX97729.1 - 0.041 13.6 0.0 0.075 12.8 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family Thioesterase PF00975.20 KFX97729.1 - 0.17 12.0 0.2 0.28 11.3 0.2 1.3 1 0 0 1 1 1 0 Thioesterase domain MOZ_SAS PF01853.18 KFX97754.1 - 8.7e-63 211.2 0.0 1.8e-62 210.1 0.0 1.5 1 0 0 1 1 1 1 MOZ/SAS family zf-MYST PF17772.1 KFX97754.1 - 2.2e-09 36.8 0.1 6.4e-09 35.3 0.1 1.9 1 0 0 1 1 1 1 MYST family zinc finger domain CorA PF01544.18 KFX97754.1 - 0.054 12.8 0.1 0.092 12.0 0.1 1.3 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein Acetyltransf_7 PF13508.7 KFX97754.1 - 0.057 13.8 0.0 0.17 12.3 0.0 1.8 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KFX97754.1 - 0.099 12.9 0.0 0.25 11.6 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family adh_short PF00106.25 KFX97755.1 - 3.5e-23 82.1 0.0 3.1e-19 69.2 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KFX97755.1 - 7.8e-13 48.5 0.0 4.7e-12 46.0 0.0 1.9 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KFX97755.1 - 1.2e-05 25.3 0.2 1.9e-05 24.7 0.2 1.2 1 0 0 1 1 1 1 KR domain AAA_16 PF13191.6 KFX97756.1 - 1.1e-08 35.6 0.0 2.8e-08 34.3 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain ATPase_2 PF01637.18 KFX97756.1 - 9.2e-05 22.5 0.0 0.00014 21.9 0.0 1.3 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea AAA_22 PF13401.6 KFX97756.1 - 0.0021 18.3 0.0 0.0059 16.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.6 KFX97756.1 - 0.0084 15.8 0.1 0.02 14.7 0.1 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_7 PF12775.7 KFX97756.1 - 0.055 13.0 0.0 0.098 12.2 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_25 PF13481.6 KFX97756.1 - 0.094 12.3 0.0 0.2 11.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain Glycos_transf_2 PF00535.26 KFX97756.1 - 0.15 11.9 0.1 3.6 7.4 0.0 2.4 2 0 0 2 2 2 0 Glycosyl transferase family 2 Myb_DNA-binding PF00249.31 KFX97757.1 - 1.6e-22 79.4 6.3 5.6e-12 45.7 0.7 3.1 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KFX97757.1 - 3.7e-18 65.5 7.2 2.3e-12 47.0 1.0 3.2 2 1 1 3 3 3 2 Myb-like DNA-binding domain MADF_DNA_bdg PF10545.9 KFX97757.1 - 0.0056 17.0 6.1 1.5 9.2 0.1 3.5 2 1 0 2 2 2 2 Alcohol dehydrogenase transcription factor Myb/SANT-like PriCT_2 PF08707.11 KFX97757.1 - 0.022 15.1 2.0 2.7 8.4 0.2 2.8 2 1 0 2 2 2 0 Primase C terminal 2 (PriCT-2) Myb_DNA-bind_4 PF13837.6 KFX97757.1 - 0.089 13.2 6.8 0.31 11.4 0.8 3.1 2 1 0 2 2 2 0 Myb/SANT-like DNA-binding domain Rap1_C PF11626.8 KFX97757.1 - 6.5 6.9 8.6 0.52 10.4 0.1 3.1 3 0 0 3 3 3 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain Fer4 PF00037.27 KFX97758.1 - 6.4e-14 51.1 16.5 3.6e-08 32.9 3.6 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_7 PF12838.7 KFX97758.1 - 3e-13 50.1 10.1 4.6e-13 49.5 10.1 1.3 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_16 PF13484.6 KFX97758.1 - 2.2e-10 41.3 8.3 3.5e-05 24.6 0.6 2.2 2 0 0 2 2 2 2 4Fe-4S double cluster binding domain Fer4_21 PF14697.6 KFX97758.1 - 3.5e-10 39.9 4.5 0.0001 22.3 0.3 2.1 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_10 PF13237.6 KFX97758.1 - 1.3e-09 38.0 20.7 8.7e-07 29.0 11.9 2.0 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_8 PF13183.6 KFX97758.1 - 6.7e-09 36.1 3.4 0.00014 22.2 0.2 2.2 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_9 PF13187.6 KFX97758.1 - 1.5e-08 34.7 10.1 3.1e-08 33.7 10.2 1.5 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_6 PF12837.7 KFX97758.1 - 6.2e-07 29.2 17.1 0.00024 21.0 5.4 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_2 PF12797.7 KFX97758.1 - 1.8e-06 27.7 11.8 0.006 16.6 1.7 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_4 PF12800.7 KFX97758.1 - 2.2e-06 27.7 10.8 0.00017 21.8 1.8 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_17 PF13534.6 KFX97758.1 - 9.2e-05 22.9 11.4 0.034 14.7 12.6 2.3 1 1 2 3 3 3 3 4Fe-4S dicluster domain c-SKI_SMAD_bind PF08782.10 KFX97758.1 - 0.0049 17.1 5.7 0.21 11.8 0.3 2.2 1 1 1 2 2 2 2 c-SKI Smad4 binding domain Fer4_18 PF13746.6 KFX97758.1 - 0.022 15.0 8.7 0.68 10.1 1.5 2.3 1 1 1 2 2 2 0 4Fe-4S dicluster domain ETF_QO PF05187.13 KFX97758.1 - 0.031 14.4 5.5 0.25 11.5 0.5 2.2 1 1 1 2 2 2 0 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S Fer4_13 PF13370.6 KFX97758.1 - 0.047 14.2 16.1 0.47 11.0 4.3 2.8 2 1 0 2 2 2 0 4Fe-4S single cluster domain of Ferredoxin I Fer4_3 PF12798.7 KFX97758.1 - 0.099 13.6 15.5 0.26 12.3 3.3 2.2 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_22 PF17179.4 KFX97758.1 - 0.19 12.6 11.4 2.3 9.1 2.0 2.2 1 1 1 2 2 2 0 4Fe-4S dicluster domain EPF PF17181.4 KFX97758.1 - 0.32 11.0 5.6 0.2 11.7 0.5 2.2 2 0 0 2 2 2 0 Epidermal patterning factor proteins Lar_restr_allev PF14354.6 KFX97758.1 - 3.6 8.1 9.7 2.8 8.4 0.8 2.4 1 1 1 2 2 2 0 Restriction alleviation protein Lar MARVEL PF01284.23 KFX97765.1 - 0.014 15.4 4.8 0.083 12.9 4.8 1.9 1 1 0 1 1 1 0 Membrane-associating domain Cytochrom_C_asm PF01578.20 KFX97765.1 - 0.018 14.8 1.3 0.031 14.1 0.1 1.8 2 0 0 2 2 2 0 Cytochrome C assembly protein Pkinase PF00069.25 KFX97766.1 - 3.5e-26 92.1 0.0 4.6e-26 91.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFX97766.1 - 8.5e-07 28.5 0.0 1.8e-06 27.5 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase Kdo PF06293.14 KFX97766.1 - 0.019 14.3 0.0 0.029 13.7 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KFX97766.1 - 0.023 14.6 0.1 0.099 12.5 0.1 1.9 2 0 0 2 2 2 0 Phosphotransferase enzyme family RIO1 PF01163.22 KFX97766.1 - 0.061 12.9 0.0 0.088 12.4 0.0 1.2 1 0 0 1 1 1 0 RIO1 family Pkinase_fungal PF17667.1 KFX97766.1 - 0.2 10.4 0.0 0.3 9.8 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase O-FucT PF10250.9 KFX97767.1 - 0.0015 18.3 0.0 0.063 13.0 0.0 2.0 1 1 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase DASH_Ask1 PF08655.10 KFX97768.1 - 9.5e-31 105.5 0.1 1.5e-30 104.8 0.1 1.3 1 0 0 1 1 1 1 DASH complex subunit Ask1 Prok-JAB PF14464.6 KFX97768.1 - 0.062 13.1 0.3 0.19 11.5 0.3 1.8 1 0 0 1 1 1 0 Prokaryotic homologs of the JAB domain DAP3 PF10236.9 KFX97791.1 - 4.9e-51 173.8 0.0 5.5e-51 173.6 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal death-associated protein 3 RhoGAP PF00620.27 KFX97792.1 - 3.3e-29 101.7 0.0 5.7e-29 100.9 0.0 1.4 1 0 0 1 1 1 1 RhoGAP domain MutS_V PF00488.21 KFX97793.1 - 2.6e-72 242.8 0.1 4.6e-72 242.0 0.1 1.4 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 KFX97793.1 - 1.5e-37 129.7 0.6 3.3e-37 128.6 0.6 1.6 1 0 0 1 1 1 1 MutS domain III MutS_I PF01624.20 KFX97793.1 - 4.9e-28 97.6 0.0 1.3e-27 96.3 0.0 1.8 1 0 0 1 1 1 1 MutS domain I MutS_II PF05188.17 KFX97793.1 - 5.7e-08 33.1 0.1 2.1e-07 31.3 0.1 2.0 1 0 0 1 1 1 1 MutS domain II MutS_IV PF05190.18 KFX97793.1 - 0.00032 21.0 0.0 0.0013 19.0 0.0 2.1 1 0 0 1 1 1 1 MutS family domain IV MRI PF15325.6 KFX97793.1 - 4.8 8.3 5.3 3.5 8.7 2.8 2.0 1 1 0 1 1 1 0 Modulator of retrovirus infection DUF2014 PF09427.10 KFX97794.1 - 0.0098 15.3 0.0 0.017 14.5 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF2014) Prenyltrans PF00432.21 KFX97796.1 - 1e-55 185.1 14.3 1.8e-11 43.6 0.0 6.2 6 0 0 6 6 6 6 Prenyltransferase and squalene oxidase repeat SQHop_cyclase_C PF13243.6 KFX97796.1 - 0.004 16.3 0.0 0.64 9.1 0.0 2.8 1 1 2 3 3 3 2 Squalene-hopene cyclase C-terminal domain SQHop_cyclase_N PF13249.6 KFX97796.1 - 0.013 14.6 0.0 7.1 5.6 0.0 3.5 3 1 2 5 5 5 0 Squalene-hopene cyclase N-terminal domain FMO-like PF00743.19 KFX97797.1 - 3.1e-13 49.0 0.1 5.5e-08 31.7 0.0 3.5 3 1 0 3 3 3 2 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 KFX97797.1 - 2.3e-11 43.5 0.0 1.4e-10 40.9 0.0 2.2 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KFX97797.1 - 7.8e-09 35.2 0.0 0.041 13.1 0.0 3.2 3 0 0 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KFX97797.1 - 1.2e-06 28.6 0.0 1.7e-05 24.9 0.0 2.6 2 0 0 2 2 2 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 KFX97797.1 - 2.1e-06 27.9 0.1 1.4e-05 25.2 0.0 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.6 KFX97797.1 - 6.5e-06 25.5 0.0 3.5e-05 23.1 0.0 2.1 1 1 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox PF00070.27 KFX97797.1 - 0.00044 20.8 0.0 13 6.5 0.0 3.4 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KFX97797.1 - 0.018 14.3 0.1 0.034 13.4 0.1 1.4 1 0 0 1 1 1 0 Thi4 family DAO PF01266.24 KFX97797.1 - 0.033 13.8 0.0 9 5.8 0.0 2.5 2 0 0 2 2 2 0 FAD dependent oxidoreductase FAD_oxidored PF12831.7 KFX97797.1 - 0.11 11.8 0.3 0.2 10.9 0.0 1.7 2 0 0 2 2 2 0 FAD dependent oxidoreductase HI0933_like PF03486.14 KFX97797.1 - 0.3 9.7 1.3 0.67 8.6 0.2 2.0 3 0 0 3 3 3 0 HI0933-like protein DUF1146 PF06612.11 KFX97798.1 - 1.1 9.4 4.0 6.2 7.0 0.9 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1146) CFEM PF05730.11 KFX97798.1 - 5.9 7.1 8.8 11 6.2 8.8 1.5 1 0 0 1 1 1 0 CFEM domain CHCH PF06747.13 KFX97799.1 - 5e-05 23.3 3.4 0.00011 22.2 3.3 1.7 1 1 1 2 2 2 1 CHCH domain MTCP1 PF08991.10 KFX97799.1 - 0.0014 18.8 1.9 0.0019 18.4 1.9 1.2 1 0 0 1 1 1 1 Mature-T-Cell Proliferation I type YqzE PF14038.6 KFX97799.1 - 0.014 15.4 1.7 0.33 11.0 0.4 2.1 2 0 0 2 2 2 0 YqzE-like protein Pet191_N PF10203.9 KFX97799.1 - 0.014 15.7 3.0 0.024 14.9 3.0 1.4 1 0 0 1 1 1 0 Cytochrome c oxidase assembly protein PET191 Cmc1 PF08583.10 KFX97799.1 - 0.026 14.5 2.7 0.87 9.7 0.5 2.3 1 1 1 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like CBM_1 PF00734.18 KFX97800.1 - 7.1e-14 51.5 15.0 2.8e-13 49.6 15.0 2.1 1 0 0 1 1 1 1 Fungal cellulose binding domain Methyltransf_15 PF09445.10 KFX97801.1 - 1.3e-41 141.9 0.1 5.7e-41 139.8 0.0 2.0 2 1 0 2 2 2 1 RNA cap guanine-N2 methyltransferase Lipase_GDSL_2 PF13472.6 KFX97801.1 - 1.7e-19 70.9 2.8 3.8e-19 69.8 1.7 2.2 2 0 0 2 2 2 1 GDSL-like Lipase/Acylhydrolase family Met_10 PF02475.16 KFX97801.1 - 5.6e-08 32.8 0.0 1.3e-07 31.6 0.0 1.5 1 0 0 1 1 1 1 Met-10+ like-protein Lipase_GDSL PF00657.22 KFX97801.1 - 3.4e-07 30.4 2.2 4.5e-07 30.0 0.1 2.2 2 1 0 2 2 2 1 GDSL-like Lipase/Acylhydrolase Cons_hypoth95 PF03602.15 KFX97801.1 - 1.6e-05 24.6 0.3 0.00013 21.7 0.0 2.3 2 0 0 2 2 2 1 Conserved hypothetical protein 95 UPF0020 PF01170.18 KFX97801.1 - 4.6e-05 23.2 0.1 0.00017 21.3 0.0 1.9 2 0 0 2 2 2 1 Putative RNA methylase family UPF0020 Methyltransf_25 PF13649.6 KFX97801.1 - 9.6e-05 23.0 0.0 0.00045 20.9 0.0 2.2 1 0 0 1 1 1 1 Methyltransferase domain DNA_methylase PF00145.17 KFX97801.1 - 0.011 15.1 0.2 0.011 15.1 0.2 2.3 2 1 0 2 2 1 0 C-5 cytosine-specific DNA methylase Methyltransf_18 PF12847.7 KFX97801.1 - 0.033 14.1 0.0 0.077 12.9 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain FliT PF05400.13 KFX97801.1 - 0.13 13.1 6.3 1 10.2 3.7 3.3 3 0 0 3 3 3 0 Flagellar protein FliT FAA_hydro_N_2 PF18288.1 KFX97801.1 - 0.36 11.3 2.1 1.3 9.4 0.8 2.5 2 0 0 2 2 2 0 Fumarylacetoacetase N-terminal domain 2 GAPT PF11770.8 KFX97801.1 - 1.8 8.4 4.1 3.1 7.6 3.4 1.6 1 1 0 1 1 1 0 GRB2-binding adapter (GAPT) GRASP55_65 PF04495.14 KFX97802.1 - 3e-46 157.2 0.0 1.9e-44 151.3 0.0 2.1 1 1 1 2 2 2 2 GRASP55/65 PDZ-like domain PDZ_6 PF17820.1 KFX97802.1 - 0.0011 18.8 0.0 0.095 12.6 0.0 2.4 2 0 0 2 2 2 2 PDZ domain Dopey_N PF04118.14 KFX97803.1 - 1.7e-118 395.2 0.1 7e-118 393.2 0.0 2.1 3 0 0 3 3 3 1 Dopey, N-terminal Mon1 PF03164.14 KFX97804.1 - 1.6e-153 511.6 0.0 1.9e-153 511.3 0.0 1.0 1 0 0 1 1 1 1 Trafficking protein Mon1 AOX PF01786.17 KFX97804.1 - 0.037 13.6 0.2 6.4 6.3 0.1 2.2 2 0 0 2 2 2 0 Alternative oxidase Pkinase_fungal PF17667.1 KFX97804.1 - 0.14 10.9 0.0 0.22 10.3 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase PHO4 PF01384.20 KFX97805.1 - 2.3e-117 391.9 22.2 2.7e-117 391.6 22.2 1.1 1 0 0 1 1 1 1 Phosphate transporter family DNA_binding_1 PF01035.20 KFX97809.1 - 1.7e-23 82.5 0.0 2.4e-23 82.0 0.0 1.2 1 0 0 1 1 1 1 6-O-methylguanine DNA methyltransferase, DNA binding domain CRAL_TRIO PF00650.20 KFX97810.1 - 9.6e-11 41.7 0.0 1.4e-10 41.1 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 KFX97810.1 - 3.6e-07 30.2 0.0 8.9e-07 29.0 0.0 1.7 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain rRNA_proc-arch PF13234.6 KFX97811.1 - 4.1e-91 305.7 0.0 9.4e-91 304.5 0.0 1.7 1 0 0 1 1 1 1 rRNA-processing arch domain DSHCT PF08148.12 KFX97811.1 - 2.7e-52 176.7 1.4 5.8e-52 175.7 0.7 1.9 2 0 0 2 2 2 1 DSHCT (NUC185) domain DEAD PF00270.29 KFX97811.1 - 1.6e-18 67.1 0.0 4.4e-18 65.7 0.0 1.8 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KFX97811.1 - 9.8e-06 25.9 0.0 5.7e-05 23.4 0.0 2.3 1 1 0 1 1 1 1 Helicase conserved C-terminal domain T2SSE PF00437.20 KFX97811.1 - 0.0044 16.1 0.0 0.047 12.8 0.0 2.4 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_22 PF13401.6 KFX97811.1 - 0.05 13.9 0.0 0.25 11.6 0.0 2.2 2 0 0 2 2 2 0 AAA domain Prp19 PF08606.11 KFX97811.1 - 0.07 13.1 0.3 5.8 7.0 0.0 2.6 2 0 0 2 2 2 0 Prp19/Pso4-like DUF3035 PF11233.8 KFX97811.1 - 0.078 13.3 6.8 0.18 12.0 6.8 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3035) AAA_16 PF13191.6 KFX97811.1 - 0.23 11.8 0.8 8.1 6.8 0.0 2.8 3 0 0 3 3 3 0 AAA ATPase domain COX7C PF02935.16 KFX97812.1 - 2.9e-24 85.1 3.3 4.9e-24 84.4 3.3 1.4 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIIc Chorismate_synt PF01264.21 KFX97813.1 - 1.5e-139 464.3 0.0 1.7e-139 464.1 0.0 1.0 1 0 0 1 1 1 1 Chorismate synthase Dicty_CAR PF05462.11 KFX97815.1 - 1.3e-12 47.4 7.8 1.3e-12 47.4 7.8 2.0 2 0 0 2 2 2 2 Slime mold cyclic AMP receptor 7tm_1 PF00001.21 KFX97815.1 - 1.2e-08 34.6 1.9 1.6e-08 34.2 1.9 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Git3 PF11710.8 KFX97815.1 - 0.00017 21.4 10.9 0.00017 21.4 10.9 1.6 2 0 0 2 2 2 1 G protein-coupled glucose receptor regulating Gpa2 Adeno_E3_CR2 PF02439.15 KFX97815.1 - 0.11 12.2 0.1 0.33 10.7 0.1 1.7 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Ank_2 PF12796.7 KFX97830.1 - 0.00048 20.7 0.0 0.0037 17.8 0.0 2.5 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KFX97830.1 - 0.0011 19.3 0.0 0.003 17.8 0.0 1.9 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFX97830.1 - 0.16 12.6 0.0 85 4.2 0.0 3.6 3 1 0 3 3 3 0 Ankyrin repeat DUF4078 PF13300.6 KFX97830.1 - 0.58 10.5 6.7 5.4 7.4 0.5 2.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4078) DUF2877 PF11392.8 KFX97830.1 - 8.3 7.2 6.3 12 6.7 0.1 3.4 3 1 1 4 4 4 0 Protein of unknown function (DUF2877) Cation_ATPase_C PF00689.21 KFX97832.1 - 6.5e-41 140.0 12.0 8.2e-41 139.7 3.0 3.0 3 0 0 3 3 3 2 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 KFX97832.1 - 2.6e-38 131.3 0.4 2.6e-38 131.3 0.4 2.7 3 0 0 3 3 3 1 E1-E2 ATPase Cation_ATPase PF13246.6 KFX97832.1 - 3.4e-20 71.9 0.0 7e-20 70.9 0.0 1.6 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 KFX97832.1 - 1.7e-18 67.7 1.5 3.1e-17 63.6 1.5 2.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 KFX97832.1 - 1.6e-06 27.7 0.1 6.3e-05 22.6 0.0 2.7 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 KFX97832.1 - 7.2e-06 25.9 0.7 9.3e-05 22.3 0.5 2.3 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DevR PF01905.16 KFX97832.1 - 0.14 11.2 0.0 0.22 10.6 0.0 1.2 1 0 0 1 1 1 0 CRISPR-associated negative auto-regulator DevR/Csa2 MatE PF01554.18 KFX97832.1 - 0.54 9.9 5.3 0.19 11.4 0.5 2.5 2 0 0 2 2 2 0 MatE DUF2976 PF11190.8 KFX97832.1 - 0.83 9.5 9.3 0.67 9.8 0.5 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF2976) HECT PF00632.25 KFX97834.1 - 1.3e-93 313.9 0.0 1.8e-93 313.4 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) WW PF00397.26 KFX97834.1 - 2.7e-32 110.5 19.0 1.5e-10 40.9 0.9 3.9 4 0 0 4 4 4 3 WW domain C2 PF00168.30 KFX97834.1 - 2.7e-18 66.1 0.0 7.3e-18 64.8 0.0 1.7 1 0 0 1 1 1 1 C2 domain Lipase_GDSL_2 PF13472.6 KFX97835.1 - 5.7e-16 59.4 0.1 9.3e-16 58.7 0.1 1.4 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 KFX97835.1 - 7.4e-10 39.1 0.0 1.3e-09 38.4 0.0 1.4 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_3 PF14606.6 KFX97835.1 - 0.13 12.4 0.0 0.2 11.8 0.0 1.4 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase family Tcf25 PF04910.14 KFX97837.1 - 9.2e-64 215.7 0.1 1.4e-63 215.1 0.1 1.3 1 0 0 1 1 1 1 Transcriptional repressor TCF25 BUD22 PF09073.10 KFX97837.1 - 7.4 5.8 38.5 0.93 8.8 24.3 2.1 2 0 0 2 2 2 0 BUD22 PP2C PF00481.21 KFX97838.1 - 3.3e-39 135.1 0.0 5.8e-39 134.3 0.0 1.3 1 0 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.12 KFX97838.1 - 0.012 15.6 0.0 2.3 8.1 0.0 2.8 3 0 0 3 3 3 0 Stage II sporulation protein E (SpoIIE) RasGEF PF00617.19 KFX97839.1 - 2.1e-50 171.4 1.4 5.4e-50 170.0 0.4 2.1 2 0 0 2 2 2 1 RasGEF domain RasGEF_N PF00618.20 KFX97839.1 - 2.2e-16 60.0 0.1 8.8e-16 58.1 0.1 2.1 1 0 0 1 1 1 1 RasGEF N-terminal motif SH3_1 PF00018.28 KFX97839.1 - 0.001 18.6 0.0 0.0026 17.3 0.0 1.8 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KFX97839.1 - 0.0088 15.9 0.0 0.017 15.0 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain DUF1115 PF06544.12 KFX97840.1 - 0.11 12.6 0.0 0.13 12.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1115) PLAC8 PF04749.17 KFX97844.1 - 1.2e-14 55.1 10.3 1.7e-14 54.6 10.3 1.2 1 0 0 1 1 1 1 PLAC8 family 7TM_GPCR_Srd PF10317.9 KFX97844.1 - 0.15 11.2 0.4 0.27 10.4 0.4 1.3 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srd Hid1 PF12722.7 KFX97845.1 - 0.31 9.1 13.8 0.32 9.1 13.8 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein SID-1_RNA_chan PF13965.6 KFX97845.1 - 0.31 9.4 0.7 0.32 9.4 0.7 1.3 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 FAM60A PF15396.6 KFX97845.1 - 0.49 10.4 16.4 0.77 9.7 16.4 1.3 1 0 0 1 1 1 0 Protein Family FAM60A SAPS PF04499.15 KFX97845.1 - 0.63 8.8 14.1 0.8 8.4 14.1 1.3 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein GAGA_bind PF06217.12 KFX97845.1 - 1.1 9.5 10.3 1.5 9.0 10.3 1.4 1 0 0 1 1 1 0 GAGA binding protein-like family Neur_chan_memb PF02932.16 KFX97845.1 - 1.8 8.6 9.3 3 7.8 9.3 1.5 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Merozoite_SPAM PF07133.11 KFX97845.1 - 5.6 6.9 42.9 9.6 6.2 42.9 1.4 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) TIP120 PF08623.10 KFX97846.1 - 2.5e-70 235.6 2.2 2.1e-68 229.3 0.1 3.7 4 0 0 4 4 4 1 TATA-binding protein interacting (TIP20) HEAT PF02985.22 KFX97846.1 - 4.7e-10 38.9 14.8 1.1 9.7 0.0 10.8 11 0 0 11 11 10 1 HEAT repeat HEAT_2 PF13646.6 KFX97846.1 - 3e-08 33.9 16.4 0.24 11.8 0.1 8.5 8 0 0 8 8 8 3 HEAT repeats RTP1_C1 PF10363.9 KFX97846.1 - 5.6e-08 32.9 11.0 0.026 14.7 0.0 6.8 7 1 0 7 7 7 2 Required for nuclear transport of RNA pol II C-terminus 1 Adaptin_N PF01602.20 KFX97846.1 - 2.1e-06 26.6 7.0 0.079 11.5 1.2 5.6 5 1 1 6 6 6 2 Adaptin N terminal region Cnd1 PF12717.7 KFX97846.1 - 6.7e-06 26.2 9.9 0.19 11.8 0.1 4.6 4 1 1 5 5 5 3 non-SMC mitotic condensation complex subunit 1 Proteasom_PSMB PF10508.9 KFX97846.1 - 7.1e-05 21.5 0.5 0.097 11.2 0.1 4.3 3 2 0 3 3 3 1 Proteasome non-ATPase 26S subunit HEAT_EZ PF13513.6 KFX97846.1 - 0.00016 22.1 24.2 18 5.9 0.8 11.4 11 2 1 12 12 12 0 HEAT-like repeat Vac14_Fab1_bd PF12755.7 KFX97846.1 - 0.00028 21.4 1.0 4 8.1 0.0 6.4 6 3 2 8 8 8 1 Vacuolar 14 Fab1-binding region CLASP_N PF12348.8 KFX97846.1 - 0.022 14.3 0.5 0.96 9.0 0.0 3.8 4 1 1 5 5 5 0 CLASP N terminal Cnd3 PF12719.7 KFX97846.1 - 0.03 13.5 0.6 9.4 5.3 0.0 4.3 5 1 0 5 5 5 0 Nuclear condensing complex subunits, C-term domain DUF3510 PF12022.8 KFX97846.1 - 0.075 13.4 0.0 0.2 12.0 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF3510) DUF4042 PF13251.6 KFX97846.1 - 0.14 11.8 7.4 18 5.0 0.0 6.2 7 1 1 8 8 8 0 Domain of unknown function (DUF4042) Importin_rep_5 PF18816.1 KFX97846.1 - 0.17 12.2 0.4 8.6 6.7 0.0 3.8 4 0 0 4 4 4 0 Importin repeat zf-C2H2_8 PF15909.5 KFX97847.1 - 0.002 18.4 2.4 0.003 17.8 2.4 1.3 1 0 0 1 1 1 1 C2H2-type zinc ribbon zf-C2H2_6 PF13912.6 KFX97847.1 - 0.0058 16.6 5.3 0.35 10.9 0.6 2.5 2 0 0 2 2 2 2 C2H2-type zinc finger FOXP-CC PF16159.5 KFX97847.1 - 0.0064 17.1 5.9 0.033 14.8 1.3 2.8 2 1 1 3 3 3 1 FOXP coiled-coil domain SpoVR PF04293.13 KFX97847.1 - 0.023 13.4 0.0 0.031 13.0 0.0 1.2 1 0 0 1 1 1 0 SpoVR like protein zf-met PF12874.7 KFX97847.1 - 0.063 13.7 6.6 2.7 8.5 0.8 2.6 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.6 KFX97847.1 - 0.065 14.1 2.8 5.5 8.1 0.3 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger CGGC PF08821.11 KFX97847.1 - 0.081 13.1 2.3 0.19 11.9 2.4 1.4 1 1 0 1 1 1 0 CGGC domain RBB1NT PF08169.11 KFX97847.1 - 0.13 12.4 0.1 0.23 11.6 0.1 1.4 1 0 0 1 1 1 0 RBB1NT (NUC162) domain zf-C2H2_9 PF16293.5 KFX97847.1 - 0.13 12.1 0.6 0.33 10.8 0.4 1.8 1 1 0 1 1 1 0 C2H2 type zinc-finger (1 copy) YscO PF07321.12 KFX97848.1 - 0.14 12.1 0.0 0.17 11.8 0.0 1.1 1 0 0 1 1 1 0 Type III secretion protein YscO DHHC PF01529.20 KFX97849.1 - 2.1e-38 131.5 7.7 3.4e-38 130.8 7.7 1.3 1 0 0 1 1 1 1 DHHC palmitoyltransferase His_Phos_1 PF00300.22 KFX97849.1 - 0.055 13.2 0.5 0.11 12.2 0.5 1.5 1 0 0 1 1 1 0 Histidine phosphatase superfamily (branch 1) DUF4064 PF13273.6 KFX97849.1 - 0.082 13.2 0.0 0.49 10.7 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4064) Rab5ip PF07019.12 KFX97849.1 - 8.9 7.0 9.7 9.8 6.8 4.8 2.4 2 0 0 2 2 2 0 Rab5-interacting protein (Rab5ip) Cyclin PF08613.11 KFX97850.1 - 2e-13 51.0 0.0 2.9e-13 50.5 0.0 1.3 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.23 KFX97850.1 - 0.0023 17.7 0.0 0.0035 17.1 0.0 1.2 1 0 0 1 1 1 1 Cyclin, N-terminal domain Chs7 PF12271.8 KFX97852.1 - 3.7e-127 423.6 15.3 4.2e-127 423.4 15.3 1.0 1 0 0 1 1 1 1 Chitin synthase export chaperone DUF3382 PF11862.8 KFX97852.1 - 5.9 7.2 13.0 0.51 10.6 2.5 3.1 2 1 1 3 3 3 0 Domain of unknown function (DUF3382) Zn_clus PF00172.18 KFX97854.1 - 1.1e-09 38.2 9.1 1.6e-09 37.7 9.1 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Opy2 PF09463.10 KFX97854.1 - 1.9 8.9 6.5 0.3 11.4 2.4 1.7 2 0 0 2 2 2 0 Opy2 protein F-box-like PF12937.7 KFX97855.1 - 0.0024 17.7 1.3 0.0043 16.9 0.0 2.0 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 KFX97855.1 - 0.018 14.9 0.0 0.018 14.9 0.0 2.3 3 0 0 3 3 3 0 F-box domain PRANC PF09372.10 KFX97855.1 - 0.11 12.8 0.2 0.2 12.0 0.2 1.3 1 0 0 1 1 1 0 PRANC domain zf-C2H2_aberr PF17017.5 KFX97857.1 - 0.00034 20.8 5.1 0.022 14.9 0.2 2.6 3 0 0 3 3 3 2 Aberrant zinc-finger zf-H2C2_2 PF13465.6 KFX97857.1 - 0.00084 19.7 8.8 0.0076 16.6 0.8 3.2 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2 PF00096.26 KFX97857.1 - 0.0016 18.8 17.0 0.06 13.8 1.6 3.5 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFX97857.1 - 0.0031 18.2 16.9 0.018 15.8 1.0 3.7 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFX97857.1 - 4.1 7.8 8.8 3.2 8.2 0.3 3.0 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding HIG_1_N PF04588.13 KFX97859.1 - 1.6e-06 28.2 0.8 2.9e-06 27.4 0.8 1.4 1 0 0 1 1 1 1 Hypoxia induced protein conserved region Kelch_1 PF01344.25 KFX97860.1 - 1.5e-41 139.7 17.2 1.3e-07 31.1 0.1 6.3 6 0 0 6 6 6 6 Kelch motif Kelch_5 PF13854.6 KFX97860.1 - 3.7e-37 125.7 14.4 4.5e-06 26.5 0.0 6.3 6 0 0 6 6 6 6 Kelch motif Kelch_3 PF13415.6 KFX97860.1 - 6.7e-34 115.5 20.2 2.3e-07 30.9 0.0 7.2 7 0 0 7 7 7 5 Galactose oxidase, central domain Kelch_4 PF13418.6 KFX97860.1 - 8.3e-34 115.4 18.6 2.9e-07 30.4 0.1 6.5 6 0 0 6 6 6 6 Galactose oxidase, central domain Kelch_2 PF07646.15 KFX97860.1 - 2.1e-31 106.7 13.7 2.8e-06 27.1 0.1 6.4 6 0 0 6 6 6 6 Kelch motif Kelch_6 PF13964.6 KFX97860.1 - 2.4e-30 103.8 17.1 3.3e-06 27.2 0.1 6.4 4 2 2 6 6 6 6 Kelch motif Dus PF01207.17 KFX97861.1 - 1.2e-40 139.6 0.0 6.5e-30 104.3 0.0 2.8 2 1 0 2 2 2 2 Dihydrouridine synthase (Dus) zf-CCCH_4 PF18044.1 KFX97861.1 - 0.0042 16.9 6.8 0.083 12.7 0.3 2.5 2 0 0 2 2 2 2 CCCH-type zinc finger GFO_IDH_MocA PF01408.22 KFX97862.1 - 3.2e-09 37.6 0.0 7.1e-09 36.5 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 KFX97862.1 - 4.4e-05 23.5 0.0 9.7e-05 22.4 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain ImpA_N PF06812.12 KFX97862.1 - 0.031 14.4 0.0 0.14 12.2 0.0 1.9 2 0 0 2 2 2 0 ImpA, N-terminal, type VI secretion system PGM_PMM_I PF02878.16 KFX97863.1 - 2.1e-31 108.5 0.3 4e-31 107.6 0.0 1.6 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I RNase_T PF00929.24 KFX97863.1 - 1.7e-27 96.9 0.1 4.5e-27 95.6 0.1 1.7 1 0 0 1 1 1 1 Exonuclease PGM_PMM_III PF02880.16 KFX97863.1 - 1.2e-24 86.7 0.0 2.5e-24 85.6 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_II PF02879.16 KFX97863.1 - 1.1e-16 61.3 0.1 3.1e-16 59.8 0.1 1.8 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.20 KFX97863.1 - 1.6e-08 34.6 0.0 4.5e-08 33.2 0.0 1.7 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain Ank_5 PF13857.6 KFX97864.1 - 1.4e-18 66.7 0.2 1e-12 48.0 0.0 4.4 4 1 1 5 5 5 2 Ankyrin repeats (many copies) VPS9 PF02204.18 KFX97864.1 - 4.5e-16 58.9 0.0 1e-15 57.8 0.0 1.6 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain Ank_2 PF12796.7 KFX97864.1 - 3.8e-15 56.2 0.0 3.7e-05 24.2 0.0 3.6 2 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KFX97864.1 - 2e-09 37.8 0.2 0.0037 17.8 0.0 4.6 2 2 2 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFX97864.1 - 6.5e-09 35.3 0.4 0.13 12.9 0.0 5.7 5 0 0 5 5 5 2 Ankyrin repeat Ank PF00023.30 KFX97864.1 - 5.7e-07 29.7 0.1 0.66 10.5 0.4 5.0 5 0 0 5 5 5 2 Ankyrin repeat PX PF00787.24 KFX97864.1 - 0.051 13.6 0.2 0.21 11.6 0.0 2.1 2 0 0 2 2 2 0 PX domain Fungal_trans_2 PF11951.8 KFX97865.1 - 2.2e-06 26.8 1.5 4e-06 25.9 1.5 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Ctr PF04145.15 KFX97866.1 - 8.5e-32 110.8 0.3 1.4e-31 110.1 0.3 1.3 1 0 0 1 1 1 1 Ctr copper transporter family DUF687 PF05095.12 KFX97866.1 - 0.32 9.5 1.2 0.52 8.8 0.3 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF687) Sod_Fe_C PF02777.18 KFX97867.1 - 9.4e-34 115.7 0.1 1.7e-33 114.8 0.1 1.4 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.22 KFX97867.1 - 2.2e-32 111.4 2.8 4.4e-32 110.4 2.8 1.5 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, alpha-hairpin domain YadA_head PF05658.14 KFX97867.1 - 0.039 14.4 1.3 0.067 13.6 1.3 1.4 1 0 0 1 1 1 0 Head domain of trimeric autotransporter adhesin Spt4 PF06093.13 KFX97878.1 - 1.2e-31 108.6 0.4 1.5e-31 108.3 0.4 1.1 1 0 0 1 1 1 1 Spt4/RpoE2 zinc finger Kin17_mid PF10357.9 KFX97879.1 - 2.4e-52 176.2 1.2 2.4e-52 176.2 1.2 1.6 2 0 0 2 2 2 1 Domain of Kin17 curved DNA-binding protein zf-met PF12874.7 KFX97879.1 - 2e-05 24.8 3.4 5.1e-05 23.5 3.4 1.7 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 KFX97879.1 - 6.1e-05 23.2 2.2 6.1e-05 23.2 2.2 2.0 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 KFX97879.1 - 0.017 15.4 0.4 0.017 15.4 0.4 2.2 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) Rotamase_2 PF13145.6 KFX97879.1 - 4.2 8.2 11.0 11 6.9 0.0 3.0 1 1 2 3 3 3 0 PPIC-type PPIASE domain Xan_ur_permease PF00860.20 KFX97880.1 - 2.3e-24 85.8 25.9 1.1e-23 83.5 25.9 2.1 1 1 0 1 1 1 1 Permease family Vta1 PF04652.16 KFX97881.1 - 1.2e-26 93.4 0.5 1.2e-26 93.4 0.5 1.5 2 0 0 2 2 2 1 Vta1 like Vta1_C PF18097.1 KFX97881.1 - 1.2e-15 56.9 0.1 2.8e-15 55.7 0.1 1.6 1 0 0 1 1 1 1 Vta1 C-terminal domain DUF2689 PF10894.8 KFX97890.1 - 0.18 11.6 0.0 0.31 10.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2689) AidB_N PF18158.1 KFX97901.1 - 1.2e-17 64.3 0.0 2e-17 63.6 0.0 1.4 1 0 0 1 1 1 1 Adaptive response protein AidB N-terminal domain Acyl-CoA_dh_1 PF00441.24 KFX97901.1 - 8.3e-17 61.8 0.0 2.2e-16 60.4 0.0 1.7 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 KFX97901.1 - 5.2e-11 42.6 0.0 1.6e-10 41.0 0.0 1.9 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain DUF3750 PF12570.8 KFX97901.1 - 0.14 12.9 1.0 0.36 11.5 1.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3750) AMP-binding PF00501.28 KFX97902.1 - 5e-45 153.8 0.0 6.9e-45 153.4 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KFX97902.1 - 0.00038 21.4 0.0 0.00086 20.2 0.0 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain HCNGP PF07818.13 KFX97902.1 - 0.16 12.6 0.3 2.3 9.0 0.0 2.7 3 0 0 3 3 3 0 HCNGP-like protein Mito_carr PF00153.27 KFX97903.1 - 2.3e-59 197.4 0.4 2.9e-20 72.0 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 KFX97903.1 - 0.17 11.0 0.5 16 4.5 0.0 2.2 2 0 0 2 2 2 0 Gammaproteobacterial serine protease Acyl-CoA_dh_N PF02771.16 KFX97904.1 - 3.9e-27 95.1 0.0 7.1e-27 94.3 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_1 PF00441.24 KFX97904.1 - 3.5e-25 89.0 0.1 5.6e-25 88.3 0.1 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 KFX97904.1 - 4.4e-18 65.3 0.0 8.7e-18 64.3 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 KFX97904.1 - 2.2e-07 31.2 0.1 3.8e-07 30.5 0.1 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain MARVEL PF01284.23 KFX97905.1 - 2.7e-14 53.4 15.4 4.4e-14 52.7 15.4 1.3 1 0 0 1 1 1 1 Membrane-associating domain YMF19 PF02326.15 KFX97905.1 - 0.37 11.6 0.0 0.37 11.6 0.0 2.2 2 0 0 2 2 2 0 Plant ATP synthase F0 ABC2_membrane_5 PF13346.6 KFX97905.1 - 0.83 9.2 12.3 3.8 7.0 12.8 1.7 1 1 0 1 1 1 0 ABC-2 family transporter protein Aldo_ket_red PF00248.21 KFX97920.1 - 3.5e-58 197.1 0.0 4.2e-58 196.9 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Maf PF02545.14 KFX97922.1 - 1.4e-41 142.1 0.0 1.7e-41 141.8 0.0 1.0 1 0 0 1 1 1 1 Maf-like protein EF-1_beta_acid PF10587.9 KFX97922.1 - 1.7 9.1 6.5 4.3 7.9 6.5 1.6 1 0 0 1 1 1 0 Eukaryotic elongation factor 1 beta central acidic region Ada3 PF10198.9 KFX97923.1 - 1.3e-47 161.2 0.6 1.3e-47 161.2 0.6 2.8 3 0 0 3 3 3 1 Histone acetyltransferases subunit 3 DUF1682 PF07946.14 KFX97923.1 - 0.44 9.7 4.2 0.83 8.8 4.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) zf-RING_2 PF13639.6 KFX97924.1 - 7.9e-13 48.5 6.6 1.5e-12 47.6 6.6 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 KFX97924.1 - 5e-08 32.5 1.9 5e-08 32.5 1.9 2.0 2 0 0 2 2 2 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 KFX97924.1 - 5.8e-08 32.4 6.4 5.8e-08 32.4 6.4 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KFX97924.1 - 1.6e-06 27.9 5.4 1.6e-06 27.9 5.4 1.7 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KFX97924.1 - 5.1e-06 26.4 7.8 1.5e-05 24.9 7.8 1.9 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 KFX97924.1 - 5.8e-06 26.2 4.1 1.1e-05 25.3 4.1 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.7 KFX97924.1 - 4.5e-05 23.7 8.5 0.00021 21.5 8.5 2.0 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_3 PF13920.6 KFX97924.1 - 0.00012 21.8 3.7 0.00026 20.8 3.7 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 KFX97924.1 - 0.0017 18.3 4.0 0.0044 17.0 3.9 1.7 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_4 PF15227.6 KFX97924.1 - 0.0071 16.5 5.3 0.019 15.1 5.3 1.8 1 1 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING-like PF08746.11 KFX97924.1 - 0.048 14.0 1.5 0.048 14.0 1.5 2.0 2 0 0 2 2 2 0 RING-like domain Prok-RING_4 PF14447.6 KFX97924.1 - 0.058 13.3 13.3 0.61 10.0 11.8 2.4 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 zf-RING_4 PF14570.6 KFX97924.1 - 0.072 12.9 3.4 0.14 12.0 3.4 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Zn_ribbon_17 PF17120.5 KFX97924.1 - 0.19 11.4 4.1 0.098 12.3 1.9 1.6 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type LapA_dom PF06305.11 KFX97924.1 - 0.29 11.0 0.8 0.71 9.7 0.8 1.6 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain PHD PF00628.29 KFX97924.1 - 0.3 11.0 3.4 0.55 10.2 3.4 1.4 1 0 0 1 1 1 0 PHD-finger zf-Nse PF11789.8 KFX97924.1 - 0.31 10.9 7.1 0.52 10.2 5.3 2.3 2 0 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit YdjO PF14169.6 KFX97924.1 - 0.33 10.7 1.2 25 4.7 0.1 2.5 2 0 0 2 2 2 0 Cold-inducible protein YdjO Methyltransf_2 PF00891.18 KFX97929.1 - 9.3e-16 57.8 0.0 1.3e-15 57.2 0.0 1.4 1 0 0 1 1 1 1 O-methyltransferase domain Dimerisation PF08100.11 KFX97929.1 - 8e-05 22.6 0.4 0.00032 20.7 0.4 2.0 1 0 0 1 1 1 1 Dimerisation domain MarR_2 PF12802.7 KFX97929.1 - 0.0016 18.3 0.1 0.0041 17.0 0.0 1.7 1 1 0 1 1 1 1 MarR family HTH_24 PF13412.6 KFX97929.1 - 0.0039 16.7 0.0 0.017 14.7 0.0 2.1 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding Dimerisation2 PF16864.5 KFX97929.1 - 0.0059 16.6 0.0 0.014 15.3 0.0 1.6 1 1 0 1 1 1 1 Dimerisation domain HTH_IclR PF09339.10 KFX97929.1 - 0.075 12.9 0.7 0.37 10.6 0.0 2.4 3 0 0 3 3 3 0 IclR helix-turn-helix domain MarR PF01047.22 KFX97929.1 - 0.1 12.6 0.0 0.23 11.4 0.0 1.5 1 0 0 1 1 1 0 MarR family DUF3164 PF11363.8 KFX97929.1 - 0.21 11.2 0.0 0.9 9.1 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3164) APH PF01636.23 KFX97930.1 - 4e-06 26.9 0.0 7.2e-06 26.1 0.0 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family DUF3731 PF12531.8 KFX97930.1 - 0.2 11.4 0.0 0.3 10.9 0.0 1.2 1 0 0 1 1 1 0 DNA-K related protein Nsp1_C PF05064.13 KFX97933.1 - 1.5e-38 131.1 2.0 1.6e-38 131.1 0.5 1.7 2 1 0 2 2 2 1 Nsp1-like C-terminal region Mod_r PF07200.13 KFX97933.1 - 0.01 15.9 0.3 0.01 15.9 0.3 2.3 1 1 1 2 2 2 0 Modifier of rudimentary (Mod(r)) protein MIP-T3_C PF17749.1 KFX97933.1 - 0.014 15.3 2.9 5.7 6.9 0.0 3.3 2 1 0 3 3 3 0 Microtubule-binding protein MIP-T3 C-terminal region DUF1664 PF07889.12 KFX97933.1 - 0.016 15.2 1.2 1.2 9.1 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) KxDL PF10241.9 KFX97933.1 - 0.02 15.2 1.5 29 5.0 0.0 3.3 1 1 1 3 3 3 0 Uncharacterized conserved protein DUF812 PF05667.11 KFX97933.1 - 0.04 12.8 4.3 0.68 8.7 5.1 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF812) Laminin_II PF06009.12 KFX97933.1 - 0.04 13.9 4.9 2.3 8.2 0.7 3.0 1 1 2 3 3 3 0 Laminin Domain II COG2 PF06148.11 KFX97933.1 - 0.062 13.4 3.1 0.55 10.3 0.5 2.5 1 1 2 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 Baculo_PEP_C PF04513.12 KFX97933.1 - 0.075 13.1 0.6 0.84 9.7 0.1 2.3 1 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus RSS_P20 PF11757.8 KFX97933.1 - 0.079 13.4 0.1 0.46 11.0 0.1 2.1 1 1 1 2 2 2 0 Suppressor of RNA silencing P21-like N-terminal domain OmpH PF03938.14 KFX97933.1 - 0.14 12.5 8.5 0.2 12.0 0.6 2.9 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) CENP-Q PF13094.6 KFX97933.1 - 0.39 10.9 5.1 0.77 10.0 5.0 1.6 1 1 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit Spc7 PF08317.11 KFX97933.1 - 0.57 9.0 7.8 0.61 8.9 1.0 2.1 2 0 0 2 2 2 0 Spc7 kinetochore protein CLZ PF16526.5 KFX97933.1 - 0.67 10.4 5.3 4.3 7.8 0.2 3.4 1 1 2 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels DUF16 PF01519.16 KFX97933.1 - 1.7 9.2 4.6 15 6.1 0.8 2.7 1 1 2 3 3 3 0 Protein of unknown function DUF16 APG6_N PF17675.1 KFX97933.1 - 3 8.4 8.1 32 5.0 5.3 2.4 1 1 1 2 2 2 0 Apg6 coiled-coil region Nucleoporin_FG PF13634.6 KFX97933.1 - 3.7 8.5 11.1 2 9.3 8.9 1.7 2 0 0 2 2 1 0 Nucleoporin FG repeat region TPPII_N PF12583.8 KFX97933.1 - 5.9 7.5 11.9 5.7 7.5 8.1 2.4 2 0 0 2 2 2 0 Tripeptidyl peptidase II N terminal TPR_MLP1_2 PF07926.12 KFX97933.1 - 6.5 6.8 11.4 0.28 11.2 1.7 2.7 2 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein IATP PF04568.12 KFX97934.1 - 6.5e-22 77.8 2.2 7.3e-22 77.6 2.2 1.0 1 0 0 1 1 1 1 Mitochondrial ATPase inhibitor, IATP 14-3-3 PF00244.20 KFX97935.1 - 1.8e-107 357.9 6.6 2.2e-107 357.6 6.6 1.0 1 0 0 1 1 1 1 14-3-3 protein Orbi_VP5 PF00901.17 KFX97935.1 - 0.082 11.3 4.3 0.14 10.5 4.3 1.3 1 0 0 1 1 1 0 Orbivirus outer capsid protein VP5 TPR_19 PF14559.6 KFX97935.1 - 0.26 11.8 3.4 0.73 10.4 0.1 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat DSPn PF14671.6 KFX97936.1 - 1.9e-42 145.1 0.0 1.8e-40 138.6 0.0 2.7 2 1 0 2 2 2 1 Dual specificity protein phosphatase, N-terminal half DSPc PF00782.20 KFX97936.1 - 2.9e-15 56.3 0.0 6.9e-15 55.0 0.0 1.6 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 KFX97936.1 - 1e-05 25.3 0.0 2.2e-05 24.2 0.0 1.5 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Pcc1 PF09341.10 KFX97937.1 - 1.4e-30 105.3 0.9 1.9e-30 104.8 0.9 1.2 1 0 0 1 1 1 1 Transcription factor Pcc1 Thioredoxin PF00085.20 KFX97938.1 - 4e-63 209.8 1.7 4.5e-30 103.7 0.0 3.8 3 0 0 3 3 3 3 Thioredoxin Thioredoxin_6 PF13848.6 KFX97938.1 - 1.2e-44 152.5 1.6 4.9e-32 111.3 0.5 3.3 2 1 1 3 3 3 3 Thioredoxin-like domain Thioredoxin_2 PF13098.6 KFX97938.1 - 8e-09 35.9 0.4 0.0014 19.0 0.0 3.3 2 1 0 2 2 2 2 Thioredoxin-like domain Thioredoxin_8 PF13905.6 KFX97938.1 - 2.8e-08 34.0 0.0 0.0065 16.8 0.0 3.8 3 1 1 4 4 4 2 Thioredoxin-like OST3_OST6 PF04756.13 KFX97938.1 - 4.7e-08 32.7 0.3 0.0062 15.9 0.0 2.9 3 0 0 3 3 3 2 OST3 / OST6 family, transporter family Calsequestrin PF01216.17 KFX97938.1 - 5.5e-08 32.2 2.7 5.5e-08 32.2 2.7 1.8 2 0 0 2 2 2 1 Calsequestrin Thioredoxin_7 PF13899.6 KFX97938.1 - 1.4e-07 31.6 0.1 0.078 13.2 0.0 3.6 3 0 0 3 3 3 2 Thioredoxin-like AhpC-TSA PF00578.21 KFX97938.1 - 3.9e-06 26.8 0.7 0.017 15.0 0.0 3.4 3 0 0 3 3 3 2 AhpC/TSA family Redoxin PF08534.10 KFX97938.1 - 0.00067 19.4 3.5 0.59 9.8 0.0 3.5 4 0 0 4 4 4 2 Redoxin YtxH PF12732.7 KFX97938.1 - 0.012 16.1 3.6 0.012 16.1 3.6 2.8 2 0 0 2 2 2 0 YtxH-like protein RRF PF01765.19 KFX97938.1 - 0.13 12.2 1.4 4.7 7.1 1.0 2.4 2 0 0 2 2 2 0 Ribosome recycling factor DUF883 PF05957.13 KFX97938.1 - 2.8 8.6 11.9 0.055 14.1 4.3 2.2 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF883) PITH PF06201.13 KFX97940.1 - 2.2e-35 122.1 0.0 3.5e-35 121.5 0.0 1.3 1 0 0 1 1 1 1 PITH domain Thioredoxin PF00085.20 KFX97940.1 - 4e-27 94.2 0.1 7.9e-27 93.3 0.1 1.5 1 0 0 1 1 1 1 Thioredoxin OST3_OST6 PF04756.13 KFX97940.1 - 8.2e-08 31.9 0.2 4.6e-07 29.5 0.1 1.9 2 0 0 2 2 2 1 OST3 / OST6 family, transporter family Thioredoxin_8 PF13905.6 KFX97940.1 - 2.1e-07 31.1 0.1 6.1e-05 23.3 0.0 2.4 1 1 1 2 2 2 2 Thioredoxin-like Thioredoxin_2 PF13098.6 KFX97940.1 - 2.1e-05 24.9 0.8 7.6e-05 23.1 0.3 2.1 2 1 0 2 2 2 1 Thioredoxin-like domain AhpC-TSA PF00578.21 KFX97940.1 - 0.0025 17.7 0.0 0.0054 16.6 0.0 1.5 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 KFX97940.1 - 0.0028 17.4 0.1 0.0074 16.0 0.1 1.7 1 0 0 1 1 1 1 Redoxin Thioredoxin_9 PF14595.6 KFX97940.1 - 0.0096 15.7 0.0 0.014 15.2 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin HyaE PF07449.11 KFX97940.1 - 0.11 12.5 0.0 0.34 10.9 0.0 1.8 2 0 0 2 2 2 0 Hydrogenase-1 expression protein HyaE Suf PF05843.14 KFX97941.1 - 2.8e-06 27.6 3.5 0.012 15.6 0.0 3.0 3 0 0 3 3 3 2 Suppressor of forked protein (Suf) TPR_14 PF13428.6 KFX97941.1 - 1.6e-05 25.3 3.9 0.083 13.7 0.1 5.1 4 3 3 7 7 7 2 Tetratricopeptide repeat DUF202 PF02656.15 KFX97942.1 - 0.0019 18.6 5.2 0.0019 18.6 5.2 1.8 1 1 1 2 2 2 1 Domain of unknown function (DUF202) Zn_clus PF00172.18 KFX97943.1 - 9e-08 32.1 6.5 1.4e-07 31.5 6.5 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Mito_carr PF00153.27 KFX97959.1 - 4e-52 174.1 5.0 4.8e-18 64.9 0.2 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein Med3 PF11593.8 KFX97959.1 - 0.29 10.3 14.7 0.42 9.8 14.7 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Ribosomal_L6 PF00347.23 KFX97962.1 - 3.5e-27 94.9 9.3 4.4e-14 52.9 1.1 2.1 2 0 0 2 2 2 2 Ribosomal protein L6 Cyclin PF08613.11 KFX97963.1 - 2.3e-08 34.6 0.0 3.7e-08 33.9 0.0 1.3 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.23 KFX97963.1 - 7.5e-05 22.5 0.0 0.00011 21.9 0.0 1.2 1 0 0 1 1 1 1 Cyclin, N-terminal domain RSN1_7TM PF02714.15 KFX97963.1 - 0.27 10.5 0.0 0.49 9.7 0.0 1.5 1 0 0 1 1 1 0 Calcium-dependent channel, 7TM region, putative phosphate PMSR PF01625.21 KFX97988.1 - 2.5e-60 203.1 0.4 3e-60 202.9 0.4 1.0 1 0 0 1 1 1 1 Peptide methionine sulfoxide reductase ArabFuran-catal PF09206.11 KFX97989.1 - 5.9e-148 492.3 16.5 8.6e-148 491.8 16.5 1.2 1 0 0 1 1 1 1 Alpha-L-arabinofuranosidase B, catalytic AbfB PF05270.13 KFX97989.1 - 2.3e-54 183.2 1.3 3.8e-54 182.5 1.3 1.4 1 0 0 1 1 1 1 Alpha-L-arabinofuranosidase B (ABFB) domain CLP_protease PF00574.23 KFX97992.1 - 3.2e-71 239.0 0.0 5.2e-71 238.3 0.0 1.3 1 1 0 1 1 1 1 Clp protease AbbA_antirepres PF14156.6 KFX97993.1 - 0.07 13.0 0.0 0.13 12.2 0.0 1.4 1 0 0 1 1 1 0 Antirepressor AbbA TPR_17 PF13431.6 KFX97994.1 - 0.00013 22.1 0.5 0.54 10.8 0.0 4.4 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_11 PF13414.6 KFX97994.1 - 0.036 13.8 0.7 11 5.8 0.0 3.8 4 0 0 4 4 4 0 TPR repeat Nro1 PF12753.7 KFX97994.1 - 0.087 11.8 0.0 0.14 11.1 0.0 1.3 1 0 0 1 1 1 0 Nuclear pore complex subunit Nro1 TPR_4 PF07721.14 KFX97994.1 - 1.1 10.1 0.1 1.1 10.1 0.1 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_2 PF07719.17 KFX97994.1 - 2.1 8.6 7.3 47 4.5 0.1 4.9 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_14 PF13428.6 KFX97994.1 - 3.6 8.7 16.4 4.8 8.3 0.0 5.9 4 2 3 7 7 7 0 Tetratricopeptide repeat NUDIX PF00293.28 KFX97995.1 - 6.7e-17 61.8 0.0 9.5e-17 61.3 0.0 1.2 1 0 0 1 1 1 1 NUDIX domain Glyco_hydro_28 PF00295.17 KFX97996.1 - 2.8e-54 184.4 9.0 4.8e-54 183.6 9.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 Pkinase PF00069.25 KFX97996.1 - 3.5e-11 43.0 0.0 7e-11 42.0 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain APH PF01636.23 KFX97996.1 - 3.1e-07 30.6 0.0 5.5e-05 23.2 0.0 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family Pkinase_Tyr PF07714.17 KFX97996.1 - 1.9e-06 27.4 0.0 3.3e-06 26.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.22 KFX97996.1 - 1.1e-05 25.1 0.0 2.1e-05 24.2 0.0 1.4 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.14 KFX97996.1 - 6.2e-05 22.4 0.0 0.00024 20.5 0.0 1.9 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.11 KFX97996.1 - 0.0039 16.3 0.0 0.008 15.3 0.0 1.5 1 0 0 1 1 1 1 Seadornavirus VP7 Pkinase_fungal PF17667.1 KFX97996.1 - 0.028 13.2 0.0 0.044 12.5 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Kinase-like PF14531.6 KFX97996.1 - 0.034 13.5 0.0 0.064 12.6 0.0 1.4 1 1 0 1 1 1 0 Kinase-like Choline_kinase PF01633.20 KFX97996.1 - 0.045 13.3 0.0 0.078 12.6 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase DJ-1_PfpI PF01965.24 KFX97997.1 - 5.4e-13 49.1 0.0 7.2e-13 48.7 0.0 1.1 1 0 0 1 1 1 1 DJ-1/PfpI family Glyco_hydro_11 PF00457.17 KFX97998.1 - 9.3e-80 266.4 22.5 1.1e-79 266.2 22.5 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 11 NmrA PF05368.13 KFX98005.1 - 2.5e-17 63.2 0.0 3.1e-17 62.9 0.0 1.0 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KFX98005.1 - 3.6e-11 43.3 0.0 4.2e-11 43.1 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KFX98005.1 - 6.4e-06 25.8 0.0 8.3e-06 25.4 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KFX98005.1 - 0.00028 20.0 0.0 0.00035 19.7 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family F420_oxidored PF03807.17 KFX98005.1 - 0.0019 18.7 0.1 0.0034 17.9 0.1 1.4 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent THF_DHG_CYH_C PF02882.19 KFX98005.1 - 0.0025 17.1 0.1 0.0037 16.6 0.1 1.3 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Shikimate_DH PF01488.20 KFX98005.1 - 0.0032 17.6 0.0 0.0051 16.9 0.0 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase DapB_N PF01113.20 KFX98005.1 - 0.009 16.1 0.0 0.013 15.7 0.0 1.3 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus Semialdhyde_dh PF01118.24 KFX98005.1 - 0.028 14.8 0.0 0.036 14.5 0.0 1.3 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain GDP_Man_Dehyd PF16363.5 KFX98005.1 - 0.11 11.9 0.0 0.14 11.5 0.0 1.2 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase Ldh_1_N PF00056.23 KFX98005.1 - 0.12 12.5 0.2 0.18 11.9 0.2 1.4 1 1 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain RmlD_sub_bind PF04321.17 KFX98005.1 - 0.13 11.3 0.0 0.17 11.0 0.0 1.1 1 0 0 1 1 1 0 RmlD substrate binding domain NAD_binding_4 PF07993.12 KFX98005.1 - 0.14 11.3 0.0 0.17 11.0 0.0 1.1 1 0 0 1 1 1 0 Male sterility protein Polysacc_synt_2 PF02719.15 KFX98005.1 - 0.15 11.2 0.0 0.19 10.9 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein NMO PF03060.15 KFX98006.1 - 3.1e-25 89.2 4.4 3.5e-20 72.6 1.3 2.1 2 0 0 2 2 2 2 Nitronate monooxygenase IMPDH PF00478.25 KFX98006.1 - 5.4e-05 22.4 4.4 0.06 12.3 0.0 2.2 1 1 1 2 2 2 2 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.18 KFX98006.1 - 6.1e-05 22.2 3.9 9.2e-05 21.6 3.9 1.2 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Glu_synthase PF01645.17 KFX98006.1 - 0.0002 20.6 0.8 0.00031 20.0 0.8 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase Antimicrobial15 PF08110.12 KFX98006.1 - 0.067 13.4 0.1 0.23 11.8 0.1 1.9 1 0 0 1 1 1 0 Ocellatin family NmrA PF05368.13 KFX98007.1 - 3.6e-41 141.2 0.1 4.4e-41 141.0 0.1 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KFX98007.1 - 1.1e-10 41.7 0.0 2.3e-10 40.7 0.0 1.5 2 0 0 2 2 2 1 NAD(P)H-binding Epimerase PF01370.21 KFX98007.1 - 0.00068 19.2 0.0 0.001 18.6 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KFX98007.1 - 0.0035 16.4 0.0 0.0047 16.0 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Sacchrp_dh_NADP PF03435.18 KFX98007.1 - 0.018 15.3 0.1 0.028 14.7 0.1 1.5 1 1 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Semialdhyde_dh PF01118.24 KFX98007.1 - 0.071 13.6 0.3 0.16 12.4 0.3 1.7 1 1 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain FAD_binding_4 PF01565.23 KFX98008.1 - 5.5e-15 55.3 0.0 9.3e-15 54.6 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain MFS_1 PF07690.16 KFX98011.1 - 2.3e-34 118.9 32.3 2.3e-34 118.9 32.3 1.7 1 1 1 2 2 2 1 Major Facilitator Superfamily Cyclin PF08613.11 KFX98020.1 - 3.9e-07 30.6 0.0 3.9e-07 30.6 0.0 2.1 2 1 0 2 2 2 1 Cyclin Cyclin_N PF00134.23 KFX98020.1 - 0.00071 19.3 0.3 0.0015 18.3 0.0 1.6 2 0 0 2 2 2 1 Cyclin, N-terminal domain GAS PF13851.6 KFX98023.1 - 0.018 14.4 1.4 0.031 13.6 1.4 1.3 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding DUF948 PF06103.11 KFX98023.1 - 0.021 15.0 0.2 0.038 14.3 0.2 1.4 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) APG6_N PF17675.1 KFX98023.1 - 0.028 14.9 0.2 0.043 14.4 0.2 1.3 1 0 0 1 1 1 0 Apg6 coiled-coil region Cep57_CLD_2 PF14197.6 KFX98023.1 - 0.034 14.2 2.7 0.057 13.5 2.7 1.3 1 0 0 1 1 1 0 Centrosome localisation domain of PPC89 DegS PF05384.11 KFX98023.1 - 0.047 13.2 0.7 0.08 12.4 0.7 1.3 1 0 0 1 1 1 0 Sensor protein DegS CENP-H PF05837.12 KFX98023.1 - 0.12 12.8 1.1 0.23 11.9 1.1 1.4 1 0 0 1 1 1 0 Centromere protein H (CENP-H) Rootletin PF15035.6 KFX98023.1 - 0.14 12.2 1.3 0.23 11.5 1.3 1.2 1 0 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion COesterase PF00135.28 KFX98025.1 - 1.1e-74 252.2 0.0 1.4e-74 251.8 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KFX98025.1 - 2.2e-06 27.7 0.2 1.1e-05 25.4 0.1 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KFX98025.1 - 0.027 13.9 0.0 0.055 12.9 0.0 1.5 1 0 0 1 1 1 0 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 KFX98025.1 - 0.084 12.1 0.0 0.14 11.4 0.0 1.2 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Ureidogly_lyase PF04115.12 KFX98025.1 - 0.13 12.0 0.0 0.22 11.3 0.0 1.3 1 0 0 1 1 1 0 Ureidoglycolate lyase Chlorophyllase2 PF12740.7 KFX98025.1 - 0.13 11.1 0.0 0.24 10.3 0.0 1.3 1 0 0 1 1 1 0 Chlorophyllase enzyme p450 PF00067.22 KFX98030.1 - 3e-44 151.5 0.0 4.3e-44 151.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Herpes_VP19C PF03327.14 KFX98031.1 - 0.073 12.5 0.0 0.086 12.3 0.0 1.1 1 0 0 1 1 1 0 Herpesvirus capsid shell protein VP19C Cytochrom_B559 PF00283.19 KFX98031.1 - 0.073 12.5 1.1 0.13 11.7 1.1 1.4 1 0 0 1 1 1 0 Cytochrome b559, alpha (gene psbE) and beta (gene psbF)subunits Alpha-amylase PF00128.24 KFX98043.1 - 1.3e-21 77.5 3.7 1.9e-15 57.3 0.8 3.1 3 0 0 3 3 3 3 Alpha amylase, catalytic domain Polysacc_deac_1 PF01522.21 KFX98045.1 - 3e-23 82.1 0.0 4.3e-23 81.5 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide deacetylase Polysacc_deac_2 PF04748.13 KFX98045.1 - 0.0068 15.6 0.0 0.014 14.5 0.0 1.5 1 0 0 1 1 1 1 Divergent polysaccharide deacetylase HTH_39 PF14090.6 KFX98045.1 - 0.018 14.7 0.1 0.047 13.5 0.1 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain pPIWI_RE_REase PF18154.1 KFX98045.1 - 0.021 14.8 0.0 0.67 9.9 0.0 2.2 2 0 0 2 2 2 0 REase associating with pPIWI_RE Epimerase PF01370.21 KFX98046.1 - 5.1e-05 22.8 0.1 0.084 12.3 0.0 2.4 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family NmrA PF05368.13 KFX98046.1 - 5.2e-05 22.9 0.0 8.3e-05 22.2 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family 3Beta_HSD PF01073.19 KFX98046.1 - 0.0026 16.8 0.5 0.039 12.9 0.5 2.1 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Semialdhyde_dh PF01118.24 KFX98046.1 - 0.0048 17.3 0.1 0.014 15.8 0.0 1.9 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain NAD_binding_4 PF07993.12 KFX98046.1 - 0.017 14.3 0.0 0.042 13.0 0.0 1.7 1 0 0 1 1 1 0 Male sterility protein AMP-binding PF00501.28 KFX98047.1 - 2.1e-93 313.2 0.0 2.7e-93 312.9 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KFX98047.1 - 1.8e-11 44.8 0.4 1.2e-10 42.2 0.7 2.3 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain Methyltransf_33 PF10017.9 KFX98049.1 - 3.1e-78 263.0 0.3 1.6e-76 257.4 0.3 2.1 1 1 0 1 1 1 1 Histidine-specific methyltransferase, SAM-dependent FGE-sulfatase PF03781.16 KFX98049.1 - 1.1e-18 67.8 0.4 1.1e-17 64.5 0.4 2.2 1 1 0 1 1 1 1 Sulfatase-modifying factor enzyme 1 DinB_2 PF12867.7 KFX98049.1 - 5.9e-05 23.6 0.0 0.00018 22.0 0.0 1.9 1 0 0 1 1 1 1 DinB superfamily DUF3246 PF11596.8 KFX98050.1 - 0.77 9.1 8.8 0.059 12.8 3.6 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3246) GATA PF00320.27 KFX98051.1 - 1.1e-29 101.7 15.8 1.2e-14 53.6 3.4 2.5 2 0 0 2 2 2 2 GATA zinc finger Zn-ribbon_8 PF09723.10 KFX98051.1 - 1.3e-05 25.2 1.9 0.064 13.4 0.1 2.6 2 0 0 2 2 2 2 Zinc ribbon domain TF_Zn_Ribbon PF08271.12 KFX98051.1 - 1.4e-05 24.5 4.2 0.031 13.8 0.2 2.5 2 0 0 2 2 2 2 TFIIB zinc-binding ArfGap PF01412.18 KFX98051.1 - 0.00012 22.1 4.1 0.22 11.6 0.3 2.7 2 0 0 2 2 2 2 Putative GTPase activating protein for Arf OrfB_Zn_ribbon PF07282.11 KFX98051.1 - 0.001 19.0 5.5 0.06 13.3 0.4 2.7 2 0 0 2 2 2 2 Putative transposase DNA-binding domain DZR PF12773.7 KFX98051.1 - 0.0034 17.4 6.0 1.5 9.0 0.2 3.1 2 1 1 3 3 3 3 Double zinc ribbon Auto_anti-p27 PF06677.12 KFX98051.1 - 0.019 15.1 8.3 0.26 11.5 0.4 2.6 3 0 0 3 3 2 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) zf-Sec23_Sec24 PF04810.15 KFX98051.1 - 0.036 14.1 0.6 0.036 14.1 0.6 2.8 3 0 0 3 3 3 0 Sec23/Sec24 zinc finger eIF-5_eIF-2B PF01873.17 KFX98051.1 - 0.037 13.9 4.9 1.6 8.6 0.4 2.4 2 0 0 2 2 2 0 Domain found in IF2B/IF5 NMD3 PF04981.13 KFX98051.1 - 0.18 11.2 1.6 5.6 6.4 0.1 2.3 2 0 0 2 2 2 0 NMD3 family zinc_ribbon_4 PF13717.6 KFX98051.1 - 0.38 10.7 1.3 4.3 7.3 0.0 2.8 2 0 0 2 2 2 0 zinc-ribbon domain DUF4757 PF15949.5 KFX98051.1 - 0.56 10.7 6.2 0.17 12.3 1.8 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4757) Rubredoxin_2 PF18073.1 KFX98051.1 - 3.6 7.4 10.2 17 5.2 0.1 4.4 4 0 0 4 4 4 0 Rubredoxin metal binding domain COPI_assoc PF08507.10 KFX98052.1 - 1.7e-34 118.7 5.8 1.8e-34 118.6 5.8 1.0 1 0 0 1 1 1 1 COPI associated protein Cg6151-P PF10233.9 KFX98052.1 - 0.0076 16.5 4.6 0.012 16.0 4.6 1.4 1 1 0 1 1 1 1 Uncharacterized conserved protein CG6151-P TMEM72 PF16054.5 KFX98052.1 - 0.022 14.4 2.1 0.022 14.4 2.1 1.6 2 0 0 2 2 2 0 Transmembrane protein family 72 DUF2583 PF10762.9 KFX98052.1 - 0.24 11.8 3.0 8.2 6.9 0.0 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF2583) YtpI PF14007.6 KFX98052.1 - 8.1 6.7 14.4 3.5 7.8 5.3 2.2 2 0 0 2 2 2 0 YtpI-like protein DUF676 PF05057.14 KFX98053.1 - 3.9e-05 23.3 0.0 0.0001 21.9 0.0 1.6 1 0 0 1 1 1 1 Putative serine esterase (DUF676) PGAP1 PF07819.13 KFX98053.1 - 4e-05 23.4 0.0 0.00011 22.0 0.0 1.7 1 0 0 1 1 1 1 PGAP1-like protein NACHT PF05729.12 KFX98053.1 - 6.5e-05 22.9 0.1 0.00013 21.9 0.1 1.6 1 0 0 1 1 1 1 NACHT domain 6PF2K PF01591.18 KFX98053.1 - 0.00038 19.8 0.0 0.0011 18.3 0.0 1.7 2 0 0 2 2 2 1 6-phosphofructo-2-kinase AAA_16 PF13191.6 KFX98053.1 - 0.00042 20.7 0.0 0.0014 19.0 0.0 1.9 2 0 0 2 2 2 1 AAA ATPase domain ANAPC4_WD40 PF12894.7 KFX98053.1 - 0.00091 19.5 0.1 0.43 10.9 0.0 4.5 3 2 3 6 6 6 1 Anaphase-promoting complex subunit 4 WD40 domain Abhydrolase_6 PF12697.7 KFX98053.1 - 0.0034 18.0 0.0 0.008 16.8 0.0 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family ATPase_2 PF01637.18 KFX98053.1 - 0.051 13.5 0.0 0.11 12.4 0.0 1.5 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_33 PF13671.6 KFX98053.1 - 0.076 13.2 0.0 0.39 10.9 0.0 2.2 2 0 0 2 2 2 0 AAA domain WD40 PF00400.32 KFX98053.1 - 0.21 12.5 2.6 41 5.3 0.1 5.2 5 0 0 5 5 5 0 WD domain, G-beta repeat Fructosamin_kin PF03881.14 KFX98054.1 - 2.7e-34 118.7 0.0 3.9e-34 118.2 0.0 1.1 1 0 0 1 1 1 1 Fructosamine kinase APH PF01636.23 KFX98054.1 - 0.0061 16.5 0.0 0.01 15.7 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family DNA_pol_phi PF04931.13 KFX98054.1 - 0.0084 14.3 13.1 0.011 13.9 13.1 1.1 1 0 0 1 1 1 1 DNA polymerase phi CDC45 PF02724.14 KFX98054.1 - 0.022 13.1 6.4 0.031 12.6 6.4 1.1 1 0 0 1 1 1 0 CDC45-like protein RXT2_N PF08595.11 KFX98054.1 - 0.069 13.2 7.1 0.12 12.4 7.1 1.2 1 0 0 1 1 1 0 RXT2-like, N-terminal TLP-20 PF06088.11 KFX98054.1 - 0.074 12.9 0.5 0.13 12.2 0.5 1.3 1 0 0 1 1 1 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) FAM176 PF14851.6 KFX98054.1 - 0.23 11.1 8.0 0.38 10.4 8.0 1.3 1 0 0 1 1 1 0 FAM176 family Cnd2 PF05786.14 KFX98054.1 - 0.39 9.3 6.3 0.57 8.8 6.3 1.1 1 0 0 1 1 1 0 Condensin complex subunit 2 Ribosomal_60s PF00428.19 KFX98054.1 - 0.49 11.0 15.7 1.3 9.6 15.7 1.7 1 0 0 1 1 1 0 60s Acidic ribosomal protein DUF4746 PF15928.5 KFX98054.1 - 0.75 9.2 12.6 1.3 8.4 12.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) Astro_capsid_p PF12226.8 KFX98054.1 - 1 8.4 10.0 1.6 7.8 10.0 1.2 1 0 0 1 1 1 0 Turkey astrovirus capsid protein Myc_N PF01056.18 KFX98054.1 - 1.3 8.9 8.1 3.8 7.3 8.1 1.7 2 0 0 2 2 2 0 Myc amino-terminal region Nop14 PF04147.12 KFX98054.1 - 1.7 6.8 14.2 2.2 6.4 14.2 1.1 1 0 0 1 1 1 0 Nop14-like family Sigma70_ner PF04546.13 KFX98054.1 - 1.7 8.5 12.3 2.7 7.8 12.3 1.2 1 0 0 1 1 1 0 Sigma-70, non-essential region Radial_spoke PF04712.12 KFX98054.1 - 1.7 7.5 14.6 3.1 6.7 14.6 1.3 1 0 0 1 1 1 0 Radial spokehead-like protein PTPRCAP PF15713.5 KFX98054.1 - 2.1 8.7 14.5 21 5.4 15.0 2.1 2 0 0 2 2 2 0 Protein tyrosine phosphatase receptor type C-associated CPSF100_C PF13299.6 KFX98054.1 - 2.7 8.1 6.1 4.2 7.5 6.1 1.2 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal SDA1 PF05285.12 KFX98054.1 - 2.9 7.2 13.6 4 6.8 13.6 1.1 1 0 0 1 1 1 0 SDA1 DUF740 PF05340.12 KFX98054.1 - 3.3 6.4 8.4 4.5 5.9 8.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF740) Paf1 PF03985.13 KFX98054.1 - 3.3 6.6 15.0 4.9 6.1 15.0 1.1 1 0 0 1 1 1 0 Paf1 TRAP_alpha PF03896.16 KFX98054.1 - 4 6.6 8.0 6 6.0 8.0 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit CobT PF06213.12 KFX98054.1 - 4 6.8 13.6 5.9 6.2 13.6 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT RNA_pol_3_Rpc31 PF11705.8 KFX98054.1 - 4.9 7.3 18.1 1.7 8.9 15.1 1.7 2 0 0 2 2 2 0 DNA-directed RNA polymerase III subunit Rpc31 Sporozoite_P67 PF05642.11 KFX98054.1 - 6.4 4.7 7.3 9.9 4.1 7.3 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen NOA36 PF06524.12 KFX98054.1 - 7.2 5.8 14.2 11 5.2 14.2 1.2 1 0 0 1 1 1 0 NOA36 protein HAD_2 PF13419.6 KFX98055.1 - 6.5e-10 39.4 0.0 1e-09 38.7 0.0 1.3 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KFX98055.1 - 2.4e-05 24.7 0.0 3.2e-05 24.3 0.0 1.1 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KFX98055.1 - 0.00014 21.8 0.0 0.00034 20.6 0.0 1.7 2 0 0 2 2 2 1 HAD-hyrolase-like MFS_1 PF07690.16 KFX98056.1 - 5.1e-15 55.3 26.3 4.7e-14 52.1 26.3 2.1 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KFX98056.1 - 2.1e-12 46.7 1.8 2.1e-12 46.7 1.8 2.5 2 1 1 3 3 3 1 Sugar (and other) transporter TRI12 PF06609.13 KFX98056.1 - 0.0021 16.5 0.4 0.0021 16.5 0.4 1.6 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) NAD_binding_10 PF13460.6 KFX98058.1 - 2.9e-05 24.0 0.0 3.3e-05 23.9 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KFX98058.1 - 0.00075 19.0 0.0 0.00096 18.7 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 KFX98058.1 - 0.01 15.0 0.0 0.018 14.2 0.0 1.4 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.12 KFX98058.1 - 0.029 13.5 0.0 0.057 12.6 0.0 1.5 1 0 0 1 1 1 0 Male sterility protein DAO PF01266.24 KFX98059.1 - 3.8e-26 92.5 1.8 4.5e-26 92.3 1.8 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Coatomer_WDAD PF04053.14 KFX98065.1 - 1.6e-146 488.9 0.0 2.5e-146 488.2 0.0 1.3 1 0 0 1 1 1 1 Coatomer WD associated region COPI_C PF06957.11 KFX98065.1 - 6.8e-93 311.6 0.0 9.6e-93 311.1 0.0 1.1 1 0 0 1 1 1 1 Coatomer (COPI) alpha subunit C-terminus WD40 PF00400.32 KFX98065.1 - 3e-35 119.6 18.1 2.6e-07 31.2 0.2 7.7 8 0 0 8 8 8 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFX98065.1 - 5.3e-07 29.9 0.4 0.07 13.4 0.0 5.4 3 2 5 8 8 8 2 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KFX98065.1 - 0.033 14.1 1.0 6.1 6.7 0.0 3.6 4 0 0 4 4 4 0 Eukaryotic translation initiation factor eIF2A MARVEL PF01284.23 KFX98065.1 - 0.051 13.6 9.1 0.092 12.8 9.1 1.4 1 0 0 1 1 1 0 Membrane-associating domain Clathrin PF00637.20 KFX98065.1 - 0.076 12.9 2.7 0.16 11.8 0.0 2.5 3 0 0 3 3 3 0 Region in Clathrin and VPS Nup160 PF11715.8 KFX98065.1 - 0.12 11.0 8.2 4.9 5.7 0.1 3.9 2 1 1 4 4 4 0 Nucleoporin Nup120/160 Glyco_transf_24 PF18404.1 KFX98066.1 - 8.8e-150 497.5 0.6 1.3e-149 496.9 0.6 1.3 1 0 0 1 1 1 1 Glucosyltransferase 24 Thioredoxin_14 PF18402.1 KFX98066.1 - 5.6e-69 232.9 0.0 1.3e-66 225.2 0.0 2.7 3 0 0 3 3 3 1 Thioredoxin-like domain Thioredoxin_15 PF18403.1 KFX98066.1 - 1.3e-47 162.5 0.1 1.2e-46 159.3 0.0 2.5 3 0 0 3 3 3 1 Thioredoxin-like domain Thioredoxin_12 PF18400.1 KFX98066.1 - 1.4e-44 152.3 0.1 6e-44 150.2 0.0 2.0 2 0 0 2 2 2 1 Thioredoxin-like domain Thioredoxin_13 PF18401.1 KFX98066.1 - 3.1e-44 150.2 3.9 2.1e-43 147.5 0.0 3.7 4 0 0 4 4 4 1 Thioredoxin-like domain UDP-g_GGTase PF06427.11 KFX98066.1 - 3.5e-38 130.1 0.0 7e-38 129.1 0.0 1.6 1 0 0 1 1 1 1 UDP-glucose:Glycoprotein Glucosyltransferase Glyco_transf_8 PF01501.20 KFX98066.1 - 0.00012 21.7 0.0 0.00024 20.7 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 8 Mito_carr PF00153.27 KFX98067.1 - 1e-57 192.1 5.9 3.4e-21 75.0 0.1 3.6 2 2 1 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 KFX98067.1 - 0.00074 18.8 3.1 0.44 9.7 0.2 3.1 1 1 2 3 3 3 3 Gammaproteobacterial serine protease APG9 PF04109.16 KFX98068.1 - 8.6e-208 691.2 10.9 1e-207 690.9 10.9 1.0 1 0 0 1 1 1 1 Autophagy protein Apg9 DUF4153 PF13687.6 KFX98068.1 - 0.85 9.2 11.1 0.038 13.6 1.1 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4153) W2 PF02020.18 KFX98069.1 - 1.8e-19 69.7 1.3 4.9e-19 68.2 1.3 1.8 1 0 0 1 1 1 1 eIF4-gamma/eIF5/eIF2-epsilon Hexapep PF00132.24 KFX98069.1 - 7.9e-06 25.4 12.1 0.0056 16.4 3.6 4.0 1 1 1 3 3 3 3 Bacterial transferase hexapeptide (six repeats) NTP_transferase PF00483.23 KFX98069.1 - 8.3e-06 25.6 0.0 1.6e-05 24.6 0.0 1.5 1 0 0 1 1 1 1 Nucleotidyl transferase DUF4954 PF16314.5 KFX98069.1 - 0.00016 20.0 2.8 0.00029 19.1 2.8 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4954) NTP_transf_3 PF12804.7 KFX98069.1 - 0.0074 16.7 0.0 0.02 15.3 0.0 1.8 1 0 0 1 1 1 1 MobA-like NTP transferase domain Fucokinase PF07959.12 KFX98069.1 - 0.0096 14.9 1.0 0.028 13.4 1.0 1.6 1 1 0 1 1 1 1 L-fucokinase Hexapep_2 PF14602.6 KFX98069.1 - 0.078 12.7 8.6 0.63 9.8 0.6 3.3 2 1 1 3 3 3 0 Hexapeptide repeat of succinyl-transferase Mito_carr PF00153.27 KFX98070.1 - 1.8e-52 175.2 1.1 2.6e-21 75.4 0.0 4.0 4 0 0 4 4 4 4 Mitochondrial carrier protein EI24 PF07264.11 KFX98073.1 - 5.5e-10 39.8 18.8 5.5e-10 39.8 18.8 1.7 2 0 0 2 2 2 1 Etoposide-induced protein 2.4 (EI24) AMP-binding PF00501.28 KFX98083.1 - 1.2e-75 254.7 0.0 1.7e-75 254.3 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme Condensation PF00668.20 KFX98083.1 - 4.7e-67 226.6 0.0 6.4e-67 226.2 0.0 1.1 1 0 0 1 1 1 1 Condensation domain NAD_binding_4 PF07993.12 KFX98083.1 - 1.5e-40 139.0 0.0 1.3e-39 135.9 0.0 2.1 1 1 0 1 1 1 1 Male sterility protein PP-binding PF00550.25 KFX98083.1 - 1.8e-18 66.6 0.8 2.9e-11 43.6 0.1 2.8 2 0 0 2 2 2 2 Phosphopantetheine attachment site Epimerase PF01370.21 KFX98083.1 - 9.9e-17 61.2 0.0 4e-16 59.2 0.0 1.9 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KFX98083.1 - 4.9e-09 35.6 0.0 8.2e-09 34.9 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 KFX98083.1 - 0.014 15.3 0.0 0.041 13.8 0.0 1.8 1 1 0 1 1 1 0 NAD(P)H-binding MFS_1 PF07690.16 KFX98084.1 - 2.1e-42 145.4 50.2 2.1e-42 145.4 50.2 2.1 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KFX98084.1 - 2.7e-14 52.9 8.4 2.7e-14 52.9 8.4 2.6 3 0 0 3 3 3 1 Sugar (and other) transporter MFS_3 PF05977.13 KFX98084.1 - 0.00036 19.1 10.2 0.00073 18.1 10.2 1.5 1 0 0 1 1 1 1 Transmembrane secretion effector DUF5337 PF17272.2 KFX98084.1 - 4.5 7.2 7.5 0.3 10.9 0.5 2.7 2 0 0 2 2 2 0 Family of unknown function (DUF5337) SAD_SRA PF02182.17 KFX98086.1 - 1.5e-28 99.5 0.1 2.3e-28 98.9 0.1 1.3 1 0 0 1 1 1 1 SAD/SRA domain Ribosomal_L18A PF01775.17 KFX98087.1 - 2.2e-54 182.7 0.6 2.9e-54 182.3 0.6 1.1 1 0 0 1 1 1 1 Ribosomal proteins 50S-L18Ae/60S-L20/60S-L18A PCI PF01399.27 KFX98088.1 - 6.3e-10 39.5 0.0 2.3e-09 37.7 0.0 2.0 2 0 0 2 2 2 1 PCI domain 7TMR-HDED PF07697.11 KFX98088.1 - 0.027 14.6 0.4 0.054 13.6 0.4 1.4 1 0 0 1 1 1 0 7TM-HD extracellular DUF1376 PF07120.11 KFX98088.1 - 0.083 13.2 0.0 0.33 11.3 0.0 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1376) TPR_19 PF14559.6 KFX98088.1 - 0.14 12.7 0.0 14 6.3 0.0 2.7 2 1 0 2 2 2 0 Tetratricopeptide repeat BTB PF00651.31 KFX98089.1 - 4.6e-08 33.3 0.0 1.7e-07 31.5 0.0 1.9 2 0 0 2 2 2 1 BTB/POZ domain Skp1_POZ PF03931.15 KFX98089.1 - 0.051 13.8 0.0 0.38 11.0 0.0 2.1 2 0 0 2 2 2 0 Skp1 family, tetramerisation domain LRR_4 PF12799.7 KFX98090.1 - 1e-32 111.6 26.9 1.4e-07 31.7 0.5 6.6 3 2 4 8 8 8 8 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KFX98090.1 - 2.4e-22 78.5 26.1 1.9e-05 24.3 3.5 5.5 3 2 2 6 6 6 5 Leucine rich repeat LRR_9 PF14580.6 KFX98090.1 - 1.2e-15 57.5 10.7 4.6e-07 29.5 1.7 3.4 1 1 2 3 3 3 3 Leucine-rich repeat KDZ PF18758.1 KFX98090.1 - 0.036 13.7 0.1 5.2 6.6 0.0 2.3 1 1 1 2 2 2 0 Kyakuja-Dileera-Zisupton transposase LRR_1 PF00560.33 KFX98090.1 - 0.047 14.2 17.8 14 6.7 0.1 7.9 9 1 0 9 9 9 0 Leucine Rich Repeat LRR_6 PF13516.6 KFX98090.1 - 0.098 12.8 0.5 0.098 12.8 0.5 7.1 8 0 0 8 8 8 0 Leucine Rich repeat FMN_dh PF01070.18 KFX98093.1 - 9.4e-100 334.0 0.0 1.3e-99 333.5 0.0 1.2 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.28 KFX98093.1 - 1.3e-19 70.1 0.0 2.8e-19 69.0 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain IMPDH PF00478.25 KFX98093.1 - 5.7e-06 25.6 0.1 0.00017 20.7 0.0 2.3 2 0 0 2 2 2 1 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.17 KFX98093.1 - 1e-05 24.9 0.0 1.7e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 Conserved region in glutamate synthase DHO_dh PF01180.21 KFX98093.1 - 0.086 12.0 0.0 0.36 10.0 0.0 1.8 2 0 0 2 2 2 0 Dihydroorotate dehydrogenase ThiG PF05690.14 KFX98093.1 - 0.099 11.9 0.0 4 6.7 0.0 2.3 2 0 0 2 2 2 0 Thiazole biosynthesis protein ThiG Sugar_tr PF00083.24 KFX98094.1 - 5.9e-19 68.3 17.7 6.6e-19 68.1 17.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter SecY PF00344.20 KFX98094.1 - 2.5 7.3 8.0 1.2 8.3 6.5 1.3 1 1 0 1 1 1 0 SecY translocase MFS_1 PF07690.16 KFX98095.1 - 3e-36 125.1 28.0 9.7e-36 123.4 28.4 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily MFS_4 PF06779.14 KFX98095.1 - 0.00037 19.9 2.6 0.00037 19.9 2.6 2.1 1 1 1 2 2 2 1 Uncharacterised MFS-type transporter YbfB DUF2499 PF10693.9 KFX98095.1 - 1.1 9.6 5.2 0.56 10.5 0.2 3.0 4 0 0 4 4 4 0 Protein of unknown function (DUF2499) FAD_binding_3 PF01494.19 KFX98096.1 - 6.7e-10 38.7 0.0 0.0041 16.4 0.0 3.1 3 0 0 3 3 3 3 FAD binding domain DAO PF01266.24 KFX98096.1 - 0.01 15.5 0.1 0.29 10.7 0.3 2.3 1 1 0 2 2 2 0 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KFX98096.1 - 0.015 15.5 0.0 0.031 14.5 0.0 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KFX98096.1 - 0.019 14.2 0.0 0.19 10.9 0.0 2.1 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KFX98096.1 - 0.11 12.5 0.0 0.22 11.5 0.0 1.5 1 0 0 1 1 1 0 FAD-NAD(P)-binding DUF3439 PF11921.8 KFX98096.1 - 0.14 12.1 0.0 0.23 11.5 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Orthoreo_P10 PF07204.11 KFX98096.1 - 0.21 11.6 0.1 0.41 10.6 0.1 1.4 1 0 0 1 1 1 0 Orthoreovirus membrane fusion protein p10 Rsm22 PF09243.10 KFX98097.1 - 5.6e-34 117.7 0.0 8.1e-33 113.9 0.0 2.7 1 1 0 1 1 1 1 Mitochondrial small ribosomal subunit Rsm22 Golgin_A5 PF09787.9 KFX98097.1 - 0.45 9.9 9.2 0.74 9.2 9.2 1.2 1 0 0 1 1 1 0 Golgin subfamily A member 5 Ribosomal_S14 PF00253.21 KFX98100.1 - 7.6e-22 76.8 0.5 1.8e-21 75.6 0.5 1.7 1 0 0 1 1 1 1 Ribosomal protein S14p/S29e adh_short PF00106.25 KFX98101.1 - 2.6e-27 95.6 0.0 4.7e-26 91.4 0.0 2.8 2 1 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 KFX98101.1 - 3.7e-18 65.9 0.0 2.6e-16 59.9 0.0 2.4 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Acetyltransf_1 PF00583.25 KFX98101.1 - 8.6e-05 22.7 0.0 0.00021 21.5 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KFX98101.1 - 0.0011 19.0 0.1 0.21 11.5 0.0 2.5 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain KR PF08659.10 KFX98101.1 - 0.0024 17.8 1.6 0.045 13.7 0.0 3.0 4 0 0 4 4 4 1 KR domain Acetyltransf_7 PF13508.7 KFX98101.1 - 0.003 17.9 0.0 0.0086 16.5 0.0 1.8 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Rpp20 PF12328.8 KFX98102.1 - 1.9e-29 102.4 0.7 2.4e-29 102.0 0.7 1.1 1 0 0 1 1 1 1 Rpp20 subunit of nuclear RNase MRP and P Alba PF01918.21 KFX98102.1 - 1.3e-11 44.2 0.0 2e-11 43.6 0.0 1.2 1 0 0 1 1 1 1 Alba Rogdi_lz PF10259.9 KFX98103.1 - 3.7e-74 249.6 0.0 5.1e-74 249.1 0.0 1.2 1 0 0 1 1 1 1 Rogdi leucine zipper containing protein Thioredoxin PF00085.20 KFX98104.1 - 6.9e-27 93.5 0.0 9.3e-27 93.0 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 KFX98104.1 - 3.3e-07 30.7 0.1 9.9e-07 29.2 0.1 1.7 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.6 KFX98104.1 - 2.7e-06 27.6 0.0 0.00062 20.0 0.0 2.1 1 1 1 2 2 2 2 Thioredoxin-like OST3_OST6 PF04756.13 KFX98104.1 - 1.4e-05 24.6 0.0 2e-05 24.1 0.0 1.2 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Redoxin PF08534.10 KFX98104.1 - 0.0001 22.0 0.1 0.19 11.5 0.0 2.2 1 1 1 2 2 2 2 Redoxin AhpC-TSA PF00578.21 KFX98104.1 - 0.00045 20.1 0.1 0.016 15.1 0.1 2.1 1 1 1 2 2 2 2 AhpC/TSA family SelK_SelG PF10961.8 KFX98104.1 - 0.0017 18.9 0.0 0.0036 17.9 0.0 1.5 1 0 0 1 1 1 1 Selenoprotein SelK_SelG HyaE PF07449.11 KFX98104.1 - 0.0051 16.7 0.0 0.0085 16.0 0.0 1.3 1 0 0 1 1 1 1 Hydrogenase-1 expression protein HyaE Thioredoxin_9 PF14595.6 KFX98104.1 - 0.0053 16.5 0.0 0.0073 16.1 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_7 PF13899.6 KFX98104.1 - 0.032 14.4 0.0 0.052 13.7 0.0 1.4 1 0 0 1 1 1 0 Thioredoxin-like Glutaredoxin PF00462.24 KFX98104.1 - 0.15 12.3 0.0 0.26 11.6 0.0 1.4 1 0 0 1 1 1 0 Glutaredoxin TraF PF13728.6 KFX98104.1 - 0.19 11.5 0.0 0.29 10.9 0.0 1.2 1 0 0 1 1 1 0 F plasmid transfer operon protein Methyltrn_RNA_3 PF02598.17 KFX98105.1 - 2.2e-70 237.4 0.0 2.5e-70 237.2 0.0 1.0 1 0 0 1 1 1 1 Putative RNA methyltransferase Rbsn PF11464.8 KFX98105.1 - 0.21 11.3 0.0 0.38 10.5 0.0 1.4 1 0 0 1 1 1 0 Rabenosyn Rab binding domain Mannosidase_ig PF17786.1 KFX98106.1 - 7.6e-14 52.1 0.1 1.6e-13 51.0 0.1 1.6 1 0 0 1 1 1 1 Mannosidase Ig/CBM-like domain Glyco_hydro_2 PF00703.21 KFX98106.1 - 1.7e-07 31.9 0.0 8.6e-07 29.6 0.0 2.1 2 0 0 2 2 2 1 Glycosyl hydrolases family 2 Glyco_hydro_2_C PF02836.17 KFX98106.1 - 0.00086 18.5 0.1 0.007 15.5 0.1 2.2 1 1 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Glyco_hydro_2_N PF02837.18 KFX98106.1 - 0.0057 16.6 0.0 0.019 14.9 0.0 1.9 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain Ig_mannosidase PF17753.1 KFX98106.1 - 0.03 14.1 0.0 0.12 12.2 0.0 2.0 1 0 0 1 1 1 0 Ig-fold domain Kinesin PF00225.23 KFX98107.1 - 1.2e-113 379.5 0.3 2.8e-113 378.2 0.3 1.7 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 KFX98107.1 - 3.8e-26 91.8 0.0 1.3e-25 90.1 0.0 2.0 1 0 0 1 1 1 1 Microtubule binding HAP1_N PF04849.13 KFX98107.1 - 0.0071 15.6 14.3 0.0071 15.6 14.3 4.2 2 1 0 3 3 3 1 HAP1 N-terminal conserved region DUF1398 PF07166.11 KFX98107.1 - 0.088 12.9 0.1 0.27 11.3 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1398) RolB_RolC PF02027.17 KFX98107.1 - 1.2 8.8 5.5 0.87 9.2 0.2 2.8 3 0 0 3 3 3 0 RolB/RolC glucosidase family UQ_con PF00179.26 KFX98108.1 - 4.3e-52 175.5 0.0 4.9e-52 175.3 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 KFX98108.1 - 0.0029 17.3 0.0 0.0032 17.2 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 KFX98108.1 - 0.032 14.5 0.0 0.037 14.3 0.0 1.3 1 1 0 1 1 1 0 RWD domain Thiolase_N PF00108.23 KFX98109.1 - 2.5e-90 302.4 0.8 4.5e-90 301.5 0.8 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 KFX98109.1 - 1.7e-36 124.6 1.3 4.2e-36 123.3 1.3 1.7 1 0 0 1 1 1 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 KFX98109.1 - 0.0028 17.3 2.2 0.0036 16.9 0.7 2.0 2 1 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.10 KFX98109.1 - 0.15 11.9 3.9 11 5.9 0.1 3.3 3 0 0 3 3 3 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III DJ-1_PfpI PF01965.24 KFX98110.1 - 1.5e-05 24.8 0.0 0.0001 22.1 0.0 2.1 1 1 0 1 1 1 1 DJ-1/PfpI family COG5 PF10392.9 KFX98120.1 - 1.3e-40 138.7 1.5 3.6e-40 137.2 1.5 1.8 1 0 0 1 1 1 1 Golgi transport complex subunit 5 DUF2434 PF10361.9 KFX98121.1 - 3.3e-131 436.6 1.7 4.4e-131 436.2 1.7 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2434) Thioredoxin PF00085.20 KFX98122.1 - 1.1e-24 86.4 0.0 1.4e-24 86.1 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 KFX98122.1 - 3.3e-08 33.9 0.1 6.2e-08 33.1 0.1 1.5 1 1 0 1 1 1 1 Thioredoxin-like domain OST3_OST6 PF04756.13 KFX98122.1 - 8.4e-07 28.6 0.3 1.4e-06 27.9 0.0 1.5 2 0 0 2 2 2 1 OST3 / OST6 family, transporter family AhpC-TSA PF00578.21 KFX98122.1 - 3.5e-06 27.0 0.1 1.6e-05 24.8 0.0 1.8 1 1 1 2 2 2 1 AhpC/TSA family Thioredoxin_8 PF13905.6 KFX98122.1 - 5.1e-06 26.7 0.0 2.1e-05 24.8 0.0 1.7 1 1 0 1 1 1 1 Thioredoxin-like Thioredoxin_7 PF13899.6 KFX98122.1 - 1.8e-05 24.9 0.0 2.4e-05 24.4 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin-like Redoxin PF08534.10 KFX98122.1 - 2e-05 24.3 0.1 4.1e-05 23.3 0.1 1.6 1 1 0 1 1 1 1 Redoxin Thioredoxin_9 PF14595.6 KFX98122.1 - 0.00011 22.0 0.0 0.00014 21.6 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_3 PF13192.6 KFX98122.1 - 0.0011 18.9 0.0 0.002 18.1 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin domain TraF PF13728.6 KFX98122.1 - 0.01 15.7 0.0 0.014 15.3 0.0 1.2 1 0 0 1 1 1 0 F plasmid transfer operon protein HyaE PF07449.11 KFX98122.1 - 0.018 15.0 0.0 0.024 14.6 0.0 1.3 1 0 0 1 1 1 0 Hydrogenase-1 expression protein HyaE Phosducin PF02114.16 KFX98122.1 - 0.041 12.8 0.0 0.053 12.5 0.0 1.1 1 0 0 1 1 1 0 Phosducin adh_short PF00106.25 KFX98123.1 - 3.5e-25 88.6 0.9 6e-25 87.9 0.7 1.4 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KFX98123.1 - 1.5e-15 57.4 1.0 1.9e-15 57.1 1.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KFX98123.1 - 2.3e-06 27.6 0.1 4.1e-06 26.8 0.1 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KFX98123.1 - 2.4e-05 23.9 0.2 0.00022 20.8 0.2 2.1 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 KFX98123.1 - 0.008 16.1 0.2 0.015 15.2 0.2 1.5 1 0 0 1 1 1 1 NAD(P)H-binding Fungal_trans_2 PF11951.8 KFX98124.1 - 1e-23 83.8 8.1 4.2e-23 81.8 8.1 1.8 1 1 0 1 1 1 1 Fungal specific transcription factor domain ABC2_membrane PF01061.24 KFX98129.1 - 1.1e-40 139.4 20.0 1.5e-40 138.9 20.0 1.2 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.27 KFX98129.1 - 7.5e-37 126.9 0.4 4.1e-18 66.2 0.0 2.7 3 0 0 3 3 2 2 ABC transporter PDR_CDR PF06422.12 KFX98129.1 - 2.4e-27 94.7 0.4 8.1e-27 93.0 0.0 2.2 2 0 0 2 2 1 1 CDR ABC transporter ABC_trans_N PF14510.6 KFX98129.1 - 2.7e-20 72.8 0.1 8.5e-20 71.2 0.1 1.9 1 0 0 1 1 1 1 ABC-transporter N-terminal AAA_16 PF13191.6 KFX98129.1 - 7.7e-08 32.9 0.2 0.0023 18.3 0.1 2.5 2 0 0 2 2 2 2 AAA ATPase domain RsgA_GTPase PF03193.16 KFX98129.1 - 1.1e-07 31.9 0.1 3e-05 24.0 0.0 2.5 2 0 0 2 2 2 1 RsgA GTPase AAA_25 PF13481.6 KFX98129.1 - 8.3e-06 25.5 0.1 8.4e-05 22.2 0.0 2.4 3 0 0 3 3 3 1 AAA domain AAA_33 PF13671.6 KFX98129.1 - 0.00018 21.7 0.1 0.069 13.3 0.1 2.6 2 0 0 2 2 2 1 AAA domain ABC2_membrane_3 PF12698.7 KFX98129.1 - 0.0004 19.6 8.0 0.0004 19.6 8.0 2.3 1 1 0 2 2 2 1 ABC-2 family transporter protein SMC_N PF02463.19 KFX98129.1 - 0.00051 19.5 0.0 0.075 12.5 0.0 3.0 3 0 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_18 PF13238.6 KFX98129.1 - 0.00084 19.9 0.0 0.055 14.0 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 KFX98129.1 - 0.0014 18.9 0.1 0.75 10.1 0.0 3.2 4 0 0 4 4 3 1 AAA domain AAA_21 PF13304.6 KFX98129.1 - 0.0021 17.9 1.6 0.37 10.5 0.0 3.1 2 1 1 3 3 3 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 KFX98129.1 - 0.0026 17.5 0.7 0.57 10.0 0.1 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_30 PF13604.6 KFX98129.1 - 0.0027 17.5 0.4 0.39 10.4 0.2 2.7 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.23 KFX98129.1 - 0.0033 17.5 0.6 1.5 9.0 0.2 2.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_17 PF13207.6 KFX98129.1 - 0.012 16.0 0.2 0.24 11.8 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 KFX98129.1 - 0.016 14.9 0.0 6.3 6.5 0.1 2.4 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 KFX98129.1 - 0.052 13.5 2.2 1.8 8.5 0.3 2.6 2 0 0 2 2 2 0 NACHT domain AAA PF00004.29 KFX98129.1 - 0.1 13.0 0.1 14 6.1 0.0 3.1 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) cobW PF02492.19 KFX98129.1 - 0.12 11.9 3.1 0.59 9.7 0.4 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_28 PF13521.6 KFX98129.1 - 0.19 11.9 0.4 1.4 9.2 0.1 2.4 2 0 0 2 2 2 0 AAA domain DUF5367 PF17329.2 KFX98129.1 - 2.4 8.3 6.2 0.26 11.4 0.6 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF5367) Git3 PF11710.8 KFX98130.1 - 1.7e-07 31.2 5.8 3.1e-07 30.4 5.8 1.3 1 0 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 7tm_1 PF00001.21 KFX98130.1 - 0.068 12.5 3.5 0.11 11.7 3.5 1.3 1 0 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) zf-CCCH_2 PF14608.6 KFX98131.1 - 1.9e-13 50.3 56.6 9.7e-07 29.0 12.2 5.5 5 0 0 5 5 5 5 RNA-binding, Nab2-type zinc finger Nab2 PF11517.8 KFX98131.1 - 0.0041 17.4 0.0 0.0073 16.6 0.0 1.4 1 0 0 1 1 1 1 Nuclear abundant poly(A) RNA-bind protein 2 (Nab2) zf-CCCH_3 PF15663.5 KFX98131.1 - 6.8 7.0 22.1 0.52 10.5 7.6 3.8 2 1 2 4 4 4 0 Zinc-finger containing family HA2 PF04408.23 KFX98132.1 - 3.3e-20 72.4 1.7 1.5e-19 70.3 0.0 2.8 3 0 0 3 3 2 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 KFX98132.1 - 1.5e-16 60.5 0.0 8.5e-16 58.1 0.0 2.3 2 0 0 2 2 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 KFX98132.1 - 3e-07 30.8 0.1 1.5e-06 28.6 0.1 2.2 1 1 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 KFX98132.1 - 7.6e-07 29.1 0.0 1.6e-06 28.1 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF2075 PF09848.9 KFX98132.1 - 0.00011 21.6 0.0 0.00024 20.5 0.0 1.6 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_22 PF13401.6 KFX98132.1 - 0.00067 19.9 0.2 0.0024 18.1 0.2 1.9 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 KFX98132.1 - 0.00075 19.3 0.0 0.0022 17.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KFX98132.1 - 0.00094 19.5 0.1 0.0024 18.2 0.1 1.6 1 0 0 1 1 1 1 AAA domain T2SSE PF00437.20 KFX98132.1 - 0.0028 16.8 0.0 0.0065 15.6 0.0 1.6 1 0 0 1 1 1 1 Type II/IV secretion system protein ResIII PF04851.15 KFX98132.1 - 0.0098 15.9 0.0 3 7.8 0.0 2.6 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit SRP54 PF00448.22 KFX98132.1 - 0.025 14.2 0.2 0.065 12.8 0.2 1.7 1 1 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_7 PF12775.7 KFX98132.1 - 0.027 14.0 0.0 0.055 13.0 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region Flavi_DEAD PF07652.14 KFX98132.1 - 0.029 14.4 0.1 0.058 13.4 0.1 1.5 1 0 0 1 1 1 0 Flavivirus DEAD domain AAA_16 PF13191.6 KFX98132.1 - 0.04 14.3 0.0 0.1 13.0 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain ATPase PF06745.13 KFX98132.1 - 0.057 12.8 0.0 0.12 11.7 0.0 1.5 1 0 0 1 1 1 0 KaiC ABC_tran PF00005.27 KFX98132.1 - 0.067 13.7 0.0 0.27 11.8 0.0 2.0 2 0 0 2 2 1 0 ABC transporter AAA_14 PF13173.6 KFX98132.1 - 0.074 13.1 0.1 0.41 10.7 0.1 2.1 1 1 0 1 1 1 0 AAA domain NACHT PF05729.12 KFX98132.1 - 0.12 12.3 0.3 0.63 9.9 0.1 2.2 2 0 0 2 2 2 0 NACHT domain GAD PF02938.14 KFX98132.1 - 0.12 12.6 0.0 0.3 11.3 0.0 1.7 1 0 0 1 1 1 0 GAD domain cobW PF02492.19 KFX98132.1 - 0.15 11.6 0.3 0.93 9.1 0.1 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_33 PF13671.6 KFX98132.1 - 0.32 11.1 0.0 0.32 11.1 0.0 2.6 3 0 0 3 3 3 0 AAA domain Ribosomal_L24e PF01246.20 KFX98134.1 - 2.5e-30 104.5 6.2 2.5e-30 104.5 6.2 1.6 2 0 0 2 2 2 1 Ribosomal protein L24e Pam16 PF03656.13 KFX98135.1 - 4.9e-08 33.0 0.2 7.8e-08 32.4 0.2 1.3 1 1 0 1 1 1 1 Pam16 DnaJ PF00226.31 KFX98135.1 - 3.4e-05 23.9 0.0 5.9e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 DnaJ domain DUF3918 PF13056.6 KFX98135.1 - 0.0014 18.2 2.3 0.0014 18.2 2.3 2.4 3 0 0 3 3 3 1 Protein of unknown function (DUF3918) TMP_2 PF06791.13 KFX98135.1 - 0.048 13.3 0.2 0.055 13.1 0.2 1.2 1 0 0 1 1 1 0 Prophage tail length tape measure protein DUF4538 PF15061.6 KFX98135.1 - 0.1 12.3 0.0 0.23 11.2 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4538) eIF3_p135 PF12807.7 KFX98136.1 - 8.5e-31 107.3 0.0 2e-30 106.1 0.0 1.7 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit 135 TPR_12 PF13424.6 KFX98136.1 - 5e-25 87.6 11.6 1.3e-10 41.4 0.1 4.2 2 1 1 4 4 4 3 Tetratricopeptide repeat TPR_10 PF13374.6 KFX98136.1 - 2.1e-22 78.3 6.9 1.2e-07 31.4 0.1 5.6 6 1 1 7 7 7 3 Tetratricopeptide repeat TPR_8 PF13181.6 KFX98136.1 - 0.00016 21.7 12.3 0.0072 16.5 0.2 4.9 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_2 PF07719.17 KFX98136.1 - 0.0024 17.8 11.5 0.061 13.5 0.1 4.9 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_1 PF00515.28 KFX98136.1 - 0.0096 15.7 3.7 2 8.4 0.4 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TAA-Trp-ring PF15401.6 KFX98136.1 - 0.081 13.4 2.0 0.21 12.1 2.0 1.6 1 0 0 1 1 1 0 Tryptophan-ring motif of head of Trimeric autotransporter adhesin DUF3888 PF13027.6 KFX98136.1 - 0.11 13.0 0.0 7.7 7.0 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3888) TPR_17 PF13431.6 KFX98136.1 - 0.17 12.3 1.6 67 4.2 0.0 3.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.6 KFX98136.1 - 3.5 7.9 5.9 6.2 7.1 0.1 4.0 5 0 0 5 5 5 0 Tetratricopeptide repeat MFS_1 PF07690.16 KFX98138.1 - 1.1e-36 126.5 23.2 1.6e-36 126.0 23.2 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF2070 PF09843.9 KFX98138.1 - 0.97 7.6 8.7 1.7 6.8 8.7 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) Thiolase_N PF00108.23 KFX98139.1 - 5.5e-66 222.6 1.2 8.4e-66 222.0 1.2 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 KFX98139.1 - 2.8e-44 149.7 0.5 6.5e-44 148.5 0.5 1.6 1 0 0 1 1 1 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 KFX98139.1 - 0.0052 16.4 2.2 0.045 13.3 2.0 2.4 2 1 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.10 KFX98139.1 - 0.011 15.6 0.2 0.56 10.1 0.1 2.5 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III ACP_syn_III_C PF08541.10 KFX98139.1 - 0.11 12.7 0.5 0.29 11.3 0.0 2.0 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal S6PP PF05116.13 KFX98141.1 - 0.076 12.5 0.0 0.1 12.1 0.0 1.1 1 0 0 1 1 1 0 Sucrose-6F-phosphate phosphohydrolase Questin_oxidase PF14027.6 KFX98142.1 - 2.6e-90 303.4 2.4 4e-90 302.8 2.4 1.3 1 0 0 1 1 1 1 Questin oxidase-like HECT_2 PF09814.9 KFX98143.1 - 1.2e-56 192.2 0.0 1.4e-56 192.0 0.0 1.0 1 0 0 1 1 1 1 HECT-like Ubiquitin-conjugating enzyme (E2)-binding MFS_1 PF07690.16 KFX98146.1 - 7.6e-24 84.3 49.8 2.8e-23 82.4 49.3 1.8 1 1 0 1 1 1 1 Major Facilitator Superfamily MFS_1_like PF12832.7 KFX98146.1 - 0.039 12.8 0.2 0.039 12.8 0.2 2.2 2 0 0 2 2 2 0 MFS_1 like family Sugar_tr PF00083.24 KFX98146.1 - 0.077 11.8 27.8 0.17 10.7 4.1 2.2 2 0 0 2 2 2 0 Sugar (and other) transporter BCNT PF07572.12 KFX98149.1 - 2.4e-25 88.4 1.3 3.8e-25 87.8 1.3 1.2 1 0 0 1 1 1 1 Bucentaur or craniofacial development zf-RING_2 PF13639.6 KFX98151.1 - 2.6e-12 46.9 3.7 4.2e-12 46.2 3.7 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 KFX98151.1 - 1.6e-10 40.5 1.2 2.8e-10 39.7 1.2 1.4 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 KFX98151.1 - 3.1e-07 30.1 3.8 5.1e-07 29.4 3.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KFX98151.1 - 5e-07 29.5 3.2 8.1e-07 28.8 3.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 KFX98151.1 - 6.1e-07 29.6 3.7 1.5e-06 28.4 3.7 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 KFX98151.1 - 6.5e-06 26.0 1.6 1.1e-05 25.3 1.6 1.4 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 KFX98151.1 - 6.5e-05 22.7 3.7 0.00015 21.5 3.7 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_3 PF13920.6 KFX98151.1 - 0.00047 20.0 1.8 0.00076 19.3 1.8 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 KFX98151.1 - 0.0097 15.9 1.1 0.021 14.9 1.1 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.6 KFX98151.1 - 0.024 14.4 3.1 0.042 13.7 3.1 1.3 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING_UBOX PF13445.6 KFX98151.1 - 0.044 13.8 5.7 0.094 12.8 5.7 1.6 1 0 0 1 1 1 0 RING-type zinc-finger Prok-RING_1 PF14446.6 KFX98151.1 - 0.12 12.3 4.1 0.086 12.8 1.6 1.9 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 PHD PF00628.29 KFX98151.1 - 0.13 12.1 2.5 0.27 11.2 2.5 1.5 1 0 0 1 1 1 0 PHD-finger zf-HC5HC2H_2 PF13832.6 KFX98151.1 - 0.16 12.2 0.0 0.3 11.3 0.0 1.4 1 0 0 1 1 1 0 PHD-zinc-finger like domain DUF5305 PF17231.2 KFX98151.1 - 0.19 11.1 0.1 0.38 10.1 0.1 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5305) Zn_ribbon_17 PF17120.5 KFX98151.1 - 0.59 9.8 2.5 1 9.1 2.5 1.3 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type FANCL_C PF11793.8 KFX98151.1 - 1 9.6 3.9 6.8 6.9 3.9 2.3 1 1 0 1 1 1 0 FANCL C-terminal domain CAP_GLY PF01302.25 KFX98152.1 - 1.3e-20 73.2 2.8 1.8e-20 72.7 2.8 1.3 1 0 0 1 1 1 1 CAP-Gly domain Ubiquitin_2 PF14560.6 KFX98152.1 - 1.3e-20 73.6 0.0 2e-20 73.1 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-like domain ubiquitin PF00240.23 KFX98152.1 - 0.00015 21.4 0.0 0.00031 20.4 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family T6_Ig_like PF18002.1 KFX98152.1 - 0.041 13.8 0.0 0.061 13.2 0.0 1.2 1 0 0 1 1 1 0 T6 antigen Ig like domain EXOSC1 PF10447.9 KFX98154.1 - 3.8e-20 72.5 4.3 9.6e-13 48.7 0.5 2.2 1 1 1 2 2 2 2 Exosome component EXOSC1/CSL4 ECR1_N PF14382.6 KFX98154.1 - 3.9e-10 39.4 0.5 8.7e-10 38.2 0.1 1.9 2 0 0 2 2 2 1 Exosome complex exonuclease RRP4 N-terminal region PCB_OB PF17092.5 KFX98154.1 - 0.076 13.8 0.2 0.13 13.0 0.2 1.3 1 0 0 1 1 1 0 Penicillin-binding protein OB-like domain tRNA_int_end_N2 PF12928.7 KFX98155.1 - 1.1e-25 89.6 0.0 2e-25 88.8 0.0 1.4 1 0 0 1 1 1 1 tRNA-splicing endonuclease subunit sen54 N-term tRNA_int_endo_N PF02778.14 KFX98155.1 - 0.017 14.8 0.0 0.035 13.8 0.0 1.4 1 0 0 1 1 1 0 tRNA intron endonuclease, N-terminal domain DUF1773 PF08593.10 KFX98155.1 - 0.18 12.8 2.2 0.31 12.1 0.3 2.5 2 0 0 2 2 2 0 Domain of unknown function zf-ZPR1 PF03367.13 KFX98156.1 - 1.6e-109 362.8 0.4 7.9e-57 191.6 0.0 2.2 2 0 0 2 2 2 2 ZPR1 zinc-finger domain Haem_bd PF14376.6 KFX98156.1 - 0.15 12.0 0.1 0.33 10.9 0.1 1.5 1 0 0 1 1 1 0 Haem-binding domain Rpr2 PF04032.16 KFX98157.1 - 9.1e-17 61.1 3.3 9.1e-17 61.1 3.3 1.6 2 0 0 2 2 2 1 RNAse P Rpr2/Rpp21/SNM1 subunit domain Nudix_N_2 PF14803.6 KFX98157.1 - 0.001 18.9 1.1 0.0031 17.4 0.1 2.2 2 0 0 2 2 2 1 Nudix N-terminal FYVE PF01363.21 KFX98157.1 - 0.0064 16.6 3.8 0.012 15.8 3.8 1.5 1 0 0 1 1 1 1 FYVE zinc finger DUF4674 PF15719.5 KFX98157.1 - 0.48 10.4 9.1 1.7 8.7 9.1 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4674) Fer4_22 PF17179.4 KFX98157.1 - 0.61 11.0 6.1 2.3 9.1 6.1 1.9 1 1 0 1 1 1 0 4Fe-4S dicluster domain C1_4 PF07975.12 KFX98157.1 - 8.3 6.7 7.8 1.5 9.2 0.6 2.7 2 1 0 2 2 2 0 TFIIH C1-like domain DBR1 PF05011.13 KFX98158.1 - 5e-45 153.3 0.0 9.2e-45 152.5 0.0 1.5 1 0 0 1 1 1 1 Lariat debranching enzyme, C-terminal domain Metallophos PF00149.28 KFX98158.1 - 3e-05 24.6 0.4 5.1e-05 23.9 0.4 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase GRP PF07172.11 KFX98158.1 - 9.7 7.0 29.3 19 6.0 29.3 1.4 1 0 0 1 1 1 0 Glycine rich protein family Skp1_POZ PF03931.15 KFX98159.1 - 2.9e-06 27.3 0.0 4.4e-06 26.8 0.0 1.3 1 0 0 1 1 1 1 Skp1 family, tetramerisation domain adh_short_C2 PF13561.6 KFX98160.1 - 5.8e-57 192.9 1.5 6.6e-57 192.7 1.5 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KFX98160.1 - 1.2e-52 178.2 1.2 1.4e-52 178.0 1.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KFX98160.1 - 8.5e-12 45.3 1.1 1.2e-11 44.8 1.1 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KFX98160.1 - 1.5e-05 24.6 0.4 7.5e-05 22.3 0.1 2.0 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 KFX98160.1 - 0.00017 20.8 0.1 0.00022 20.4 0.1 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.6 KFX98160.1 - 0.00045 20.2 0.4 0.00054 19.9 0.4 1.3 1 0 0 1 1 1 1 NAD(P)H-binding DFP PF04127.15 KFX98160.1 - 0.0013 18.6 0.3 0.005 16.7 0.0 1.9 2 0 0 2 2 2 1 DNA / pantothenate metabolism flavoprotein ApbA PF02558.16 KFX98160.1 - 0.0031 17.2 0.2 0.0055 16.4 0.2 1.4 1 1 0 1 1 1 1 Ketopantoate reductase PanE/ApbA 3HCDH_N PF02737.18 KFX98160.1 - 0.0048 16.8 0.2 0.0073 16.2 0.2 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DapB_N PF01113.20 KFX98160.1 - 0.059 13.5 0.1 0.11 12.6 0.1 1.5 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus THF_DHG_CYH_C PF02882.19 KFX98160.1 - 0.095 12.0 0.1 1.5 8.1 0.1 2.2 1 1 1 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain F420_oxidored PF03807.17 KFX98160.1 - 0.14 12.7 0.9 1.2 9.8 0.9 2.3 1 1 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent ThiF PF00899.21 KFX98161.1 - 7.9e-73 244.8 0.0 1.2e-72 244.2 0.0 1.1 1 0 0 1 1 1 1 ThiF family UAE_UbL PF14732.6 KFX98161.1 - 6.7e-25 87.5 0.9 6.7e-25 87.5 0.9 1.9 2 0 0 2 2 2 1 Ubiquitin/SUMO-activating enzyme ubiquitin-like domain UBA_e1_thiolCys PF10585.9 KFX98161.1 - 5.9e-08 32.9 2.9 4.2e-06 26.9 1.1 2.7 1 1 1 2 2 2 2 Ubiquitin-activating enzyme active site NAD_binding_7 PF13241.6 KFX98161.1 - 0.00063 20.2 0.7 0.003 18.0 0.0 2.5 3 0 0 3 3 3 1 Putative NAD(P)-binding Shikimate_DH PF01488.20 KFX98161.1 - 0.0079 16.3 0.0 0.02 15.0 0.0 1.8 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Pyr_redox PF00070.27 KFX98161.1 - 0.083 13.5 0.1 1.6 9.3 0.0 2.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DUF2407_C PF13373.6 KFX98161.1 - 0.15 12.2 0.7 0.35 11.0 0.7 1.6 1 0 0 1 1 1 0 DUF2407 C-terminal domain Endonuc_Holl PF10107.9 KFX98161.1 - 0.27 11.1 0.0 0.27 11.1 0.0 2.0 3 0 0 3 3 3 0 Endonuclease related to archaeal Holliday junction resolvase PRKG1_interact PF15898.5 KFX98161.1 - 5.4 8.0 6.0 8 7.4 0.4 2.7 3 0 0 3 3 3 0 cGMP-dependent protein kinase interacting domain Q_salvage PF10343.9 KFX98162.1 - 1.4e-129 431.6 0.5 1.7e-129 431.4 0.5 1.1 1 0 0 1 1 1 1 Potential Queuosine, Q, salvage protein family Spore_YhaL PF14147.6 KFX98162.1 - 0.12 12.1 0.0 0.25 11.0 0.0 1.5 1 0 0 1 1 1 0 Sporulation protein YhaL Sacchrp_dh_NADP PF03435.18 KFX98177.1 - 1.4e-20 73.9 1.5 2.1e-20 73.3 0.7 1.7 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain Semialdhyde_dh PF01118.24 KFX98177.1 - 0.0021 18.5 0.0 0.0043 17.5 0.0 1.6 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain KR PF08659.10 KFX98177.1 - 0.006 16.5 0.1 0.012 15.6 0.1 1.4 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 KFX98177.1 - 0.0078 15.4 0.1 0.013 14.7 0.1 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Aldolase PF01081.19 KFX98177.1 - 0.027 13.9 0.0 0.054 12.9 0.0 1.4 1 0 0 1 1 1 0 KDPG and KHG aldolase NmrA PF05368.13 KFX98177.1 - 0.039 13.5 0.3 0.087 12.4 0.3 1.6 1 1 0 1 1 1 0 NmrA-like family Ank_4 PF13637.6 KFX98178.1 - 1.2e-06 28.9 0.0 0.73 10.5 0.0 4.6 3 1 0 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFX98178.1 - 0.0023 18.3 2.0 95 4.1 0.0 6.0 7 0 0 7 7 7 0 Ankyrin repeat F-box-like PF12937.7 KFX98178.1 - 0.023 14.6 1.1 0.096 12.6 0.0 2.6 3 0 0 3 3 3 0 F-box-like F-box PF00646.33 KFX98178.1 - 0.027 14.3 0.5 0.067 13.1 0.0 1.9 2 0 0 2 2 2 0 F-box domain Ank_2 PF12796.7 KFX98178.1 - 0.073 13.7 0.1 11 6.7 0.1 3.1 3 0 0 3 3 3 0 Ankyrin repeats (3 copies) Asp PF00026.23 KFX98179.1 - 2.2e-69 234.3 6.0 2.6e-69 234.0 6.0 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KFX98179.1 - 3.4e-12 47.0 5.1 1.8e-06 28.3 0.1 2.7 2 1 1 3 3 3 2 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 KFX98179.1 - 0.0016 19.0 0.6 0.055 14.1 0.2 3.1 2 1 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.6 KFX98179.1 - 0.041 14.4 0.3 0.44 11.1 0.2 2.7 2 1 0 2 2 2 0 gag-polyprotein putative aspartyl protease RHD3 PF05879.12 KFX98180.1 - 0 1045.5 0.0 0 1045.3 0.0 1.0 1 0 0 1 1 1 1 Root hair defective 3 GTP-binding protein (RHD3) GBP PF02263.19 KFX98180.1 - 1.3e-07 31.2 0.1 2.1e-07 30.5 0.1 1.2 1 0 0 1 1 1 1 Guanylate-binding protein, N-terminal domain Dynamin_N PF00350.23 KFX98180.1 - 2.2e-05 24.6 0.0 3.9e-05 23.8 0.0 1.4 1 0 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.23 KFX98180.1 - 0.00022 21.3 0.0 0.00052 20.1 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_28 PF13521.6 KFX98180.1 - 0.0054 17.0 0.0 0.02 15.1 0.0 2.1 1 0 0 1 1 1 1 AAA domain DSBA PF01323.20 KFX98180.1 - 0.13 12.0 0.0 0.26 11.1 0.0 1.4 1 0 0 1 1 1 0 DSBA-like thioredoxin domain RNase_HII PF01351.18 KFX98181.1 - 3e-62 210.0 0.0 3.1e-41 141.4 0.0 3.1 2 1 1 3 3 3 3 Ribonuclease HII Mif2_N PF15624.6 KFX98182.1 - 1.9e-36 125.8 4.7 1.9e-36 125.8 4.7 3.4 2 1 0 3 3 3 1 Kinetochore CENP-C fungal homologue, Mif2, N-terminal CENP-C_C PF11699.8 KFX98182.1 - 4.2e-31 107.0 0.0 6.6e-31 106.4 0.0 1.3 1 0 0 1 1 1 1 Mif2/CENP-C like Cupin_2 PF07883.11 KFX98182.1 - 2.5e-10 39.9 0.0 4.7e-10 39.0 0.0 1.4 1 0 0 1 1 1 1 Cupin domain Cupin_1 PF00190.22 KFX98182.1 - 0.0013 18.3 0.1 0.0027 17.3 0.1 1.4 1 0 0 1 1 1 1 Cupin Cupin_3 PF05899.12 KFX98182.1 - 0.015 15.0 0.0 0.038 13.7 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF861) Fructosamin_kin PF03881.14 KFX98183.1 - 6.9e-70 235.5 0.0 7.5e-70 235.4 0.0 1.0 1 0 0 1 1 1 1 Fructosamine kinase APH PF01636.23 KFX98183.1 - 3e-05 24.1 0.0 4.9e-05 23.4 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family DUF1679 PF07914.11 KFX98183.1 - 0.011 14.7 0.0 0.017 14.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) EcKinase PF02958.20 KFX98183.1 - 0.1 11.9 0.0 0.17 11.2 0.0 1.2 1 0 0 1 1 1 0 Ecdysteroid kinase RE_MjaI PF09568.10 KFX98183.1 - 0.18 11.6 0.0 0.33 10.8 0.0 1.3 1 0 0 1 1 1 0 MjaI restriction endonuclease TAF4 PF05236.14 KFX98184.1 - 8.1e-29 101.2 0.0 3.8e-25 89.2 0.1 2.2 2 0 0 2 2 2 2 Transcription initiation factor TFIID component TAF4 family CPSF73-100_C PF11718.8 KFX98185.1 - 1.3e-88 296.1 0.0 1.9e-88 295.6 0.0 1.2 1 0 0 1 1 1 1 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term Beta-Casp PF10996.8 KFX98185.1 - 2.1e-29 102.0 0.0 4e-29 101.1 0.0 1.5 1 0 0 1 1 1 1 Beta-Casp domain Lactamase_B PF00753.27 KFX98185.1 - 2.1e-19 70.3 0.4 2.1e-19 70.3 0.4 1.8 2 0 0 2 2 2 1 Metallo-beta-lactamase superfamily Lactamase_B_6 PF16661.5 KFX98185.1 - 3.5e-18 65.7 0.1 5.8e-18 65.0 0.1 1.3 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily domain RMMBL PF07521.12 KFX98185.1 - 6.8e-12 45.1 0.0 1.4e-11 44.1 0.0 1.5 1 0 0 1 1 1 1 Zn-dependent metallo-hydrolase RNA specificity domain Lactamase_B_2 PF12706.7 KFX98185.1 - 7.3e-06 25.6 0.6 1.8e-05 24.3 0.3 1.8 2 0 0 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 KFX98185.1 - 0.00016 21.6 0.1 0.00037 20.4 0.1 1.6 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Beta_lactamase3 PF17030.5 KFX98185.1 - 0.092 12.0 0.0 0.16 11.2 0.0 1.3 1 0 0 1 1 1 0 Putative beta-lactamase-like family CN_hydrolase PF00795.22 KFX98186.1 - 4.1e-54 183.7 0.1 4.6e-54 183.5 0.1 1.0 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Mito_carr PF00153.27 KFX98187.1 - 1.9e-51 172.0 2.4 3.8e-18 65.2 0.2 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein TrbI_Ftype PF09677.10 KFX98188.1 - 0.62 10.4 2.6 1.7 9.0 2.6 1.7 1 0 0 1 1 1 0 Type-F conjugative transfer system protein (TrbI_Ftype) Prefoldin_2 PF01920.20 KFX98189.1 - 3.8e-20 71.8 3.7 4.8e-20 71.5 3.7 1.1 1 0 0 1 1 1 1 Prefoldin subunit FlxA PF14282.6 KFX98189.1 - 0.0047 16.9 8.0 0.23 11.4 5.8 2.2 2 0 0 2 2 2 1 FlxA-like protein Rootletin PF15035.6 KFX98189.1 - 0.02 14.9 2.7 0.14 12.2 0.0 2.0 2 0 0 2 2 2 0 Ciliary rootlet component, centrosome cohesion ADIP PF11559.8 KFX98189.1 - 0.037 14.1 4.3 1.4 9.0 0.0 2.1 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding Tropomyosin_1 PF12718.7 KFX98189.1 - 0.055 13.6 2.9 1.6 8.9 0.1 2.1 2 0 0 2 2 2 0 Tropomyosin like MetOD2 PF18548.1 KFX98189.1 - 0.056 13.5 6.1 0.085 13.0 0.2 2.7 2 1 1 3 3 3 0 Metanogen output domain 2 GM_CSF PF01109.17 KFX98189.1 - 0.12 12.6 1.0 0.28 11.3 0.4 1.7 1 1 1 2 2 2 0 Granulocyte-macrophage colony-stimulating factor CC2-LZ PF16516.5 KFX98189.1 - 0.13 12.7 4.5 3.2 8.2 1.3 2.2 2 0 0 2 2 2 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator BLOC1_2 PF10046.9 KFX98189.1 - 0.13 12.6 5.4 0.48 10.8 0.1 2.3 2 1 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Rho_Binding PF08912.11 KFX98189.1 - 0.17 12.8 3.7 0.97 10.3 0.1 2.2 2 0 0 2 2 2 0 Rho Binding Tektin PF03148.14 KFX98189.1 - 0.32 9.7 7.7 2.5 6.8 7.7 1.9 1 1 0 1 1 1 0 Tektin family Fungal_TACC PF12709.7 KFX98189.1 - 0.54 10.7 5.1 1.6 9.3 0.1 2.3 2 0 0 2 2 2 0 Fungal Transforming acidic coiled-coil (TACC) proteins YabA PF06156.13 KFX98189.1 - 0.55 10.9 7.1 49 4.6 7.1 2.1 1 1 0 1 1 1 0 Initiation control protein YabA Fib_alpha PF08702.10 KFX98189.1 - 0.6 10.3 9.0 0.54 10.4 0.1 2.1 1 1 0 2 2 2 0 Fibrinogen alpha/beta chain family USP8_interact PF08941.10 KFX98189.1 - 2.9 7.7 6.2 1.8 8.4 3.8 1.7 1 1 1 2 2 2 0 USP8 interacting Proteasome PF00227.26 KFX98193.1 - 9.9e-05 21.9 0.3 0.00012 21.6 0.3 1.2 1 0 0 1 1 1 1 Proteasome subunit DUF4270 PF14092.6 KFX98193.1 - 0.027 13.6 0.0 0.027 13.6 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4270) HCNGP PF07818.13 KFX98194.1 - 6.6e-35 119.6 0.6 1.2e-34 118.8 0.6 1.4 1 0 0 1 1 1 1 HCNGP-like protein Pkinase PF00069.25 KFX98195.1 - 5.5e-74 248.8 0.0 1.1e-73 247.8 0.0 1.5 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFX98195.1 - 1.4e-36 126.1 0.0 2.1e-36 125.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.26 KFX98195.1 - 3.4e-17 62.5 0.1 7.4e-17 61.5 0.1 1.6 1 0 0 1 1 1 1 FHA domain Kinase-like PF14531.6 KFX98195.1 - 7.2e-08 32.1 0.0 3.4e-06 26.6 0.0 2.2 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 KFX98195.1 - 4.1e-06 25.8 0.0 7e-06 25.1 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Yop-YscD_cpl PF16697.5 KFX98195.1 - 5.2e-06 26.7 0.0 1.3e-05 25.4 0.0 1.6 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain Kdo PF06293.14 KFX98195.1 - 0.016 14.6 0.2 0.03 13.7 0.2 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pox_ser-thr_kin PF05445.11 KFX98195.1 - 0.026 13.5 0.3 0.053 12.5 0.1 1.5 2 0 0 2 2 2 0 Poxvirus serine/threonine protein kinase FTA2 PF13095.6 KFX98195.1 - 0.036 13.7 0.4 6.5 6.3 0.0 2.5 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 KFX98195.1 - 0.052 13.5 0.1 0.18 11.7 0.1 1.9 1 1 0 1 1 1 0 Phosphotransferase enzyme family DUF2961 PF11175.8 KFX98195.1 - 0.078 12.6 0.0 0.14 11.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2961) RIO1 PF01163.22 KFX98195.1 - 0.11 12.0 0.5 0.3 10.7 0.3 1.7 1 1 1 2 2 2 0 RIO1 family MDM31_MDM32 PF08118.11 KFX98196.1 - 1.6e-253 842.1 0.1 2.2e-253 841.7 0.1 1.2 1 0 0 1 1 1 1 Yeast mitochondrial distribution and morphology (MDM) proteins PsaX PF08078.12 KFX98196.1 - 0.11 12.5 1.0 0.27 11.2 1.0 1.6 1 0 0 1 1 1 0 PsaX family DUF3645 PF12359.8 KFX98196.1 - 0.19 11.1 0.6 0.53 9.7 0.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3645) KH_8 PF17903.1 KFX98197.1 - 0.00027 20.9 0.0 0.00053 20.0 0.0 1.4 1 0 0 1 1 1 1 Krr1 KH1 domain KH_1 PF00013.29 KFX98197.1 - 0.036 13.9 1.0 0.084 12.7 1.0 1.6 1 0 0 1 1 1 0 KH domain Peptidase_C48 PF02902.19 KFX98198.1 - 5.3e-16 59.1 0.1 2.4e-15 57.0 0.1 2.0 1 1 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain DUF4951 PF16309.5 KFX98198.1 - 0.013 15.5 0.0 0.042 13.9 0.0 1.8 2 0 0 2 2 2 0 Domian of unknown function (DUF4951) Cation_efflux PF01545.21 KFX98199.1 - 9.8e-22 77.7 10.7 1.2e-21 77.4 10.7 1.1 1 0 0 1 1 1 1 Cation efflux family ZT_dimer PF16916.5 KFX98199.1 - 8.2e-06 25.9 0.0 1.6e-05 24.9 0.0 1.4 1 0 0 1 1 1 1 Dimerisation domain of Zinc Transporter adh_short PF00106.25 KFX98200.1 - 6.6e-42 143.2 0.4 9.6e-42 142.7 0.4 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KFX98200.1 - 2.4e-29 102.6 0.1 2.9e-29 102.3 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF1776 PF08643.10 KFX98200.1 - 9.8e-05 21.9 0.0 0.0096 15.3 0.1 2.2 2 1 0 2 2 2 2 Fungal family of unknown function (DUF1776) ApbA PF02558.16 KFX98200.1 - 0.052 13.2 0.0 0.085 12.5 0.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA AP_endonuc_2 PF01261.24 KFX98201.1 - 7.1e-30 104.0 0.0 9.3e-30 103.6 0.0 1.3 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel SLX9 PF15341.6 KFX98202.1 - 1.1e-39 135.9 4.4 1.5e-39 135.4 4.4 1.2 1 0 0 1 1 1 1 Ribosome biogenesis protein SLX9 DUF4515 PF14988.6 KFX98203.1 - 0.018 14.9 1.0 0.053 13.4 1.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4515) FCH PF00611.23 KFX98203.1 - 0.069 13.4 0.3 0.21 11.9 0.3 1.9 1 0 0 1 1 1 0 Fes/CIP4, and EFC/F-BAR homology domain HEPN PF05168.14 KFX98203.1 - 0.07 13.3 0.0 0.18 11.9 0.0 1.6 1 0 0 1 1 1 0 HEPN domain AIG2_2 PF13772.6 KFX98204.1 - 0.00012 22.4 0.2 0.00069 20.0 0.2 2.1 1 1 0 1 1 1 1 AIG2-like family Pkinase PF00069.25 KFX98211.1 - 1e-33 116.8 0.0 1.7e-32 112.8 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFX98211.1 - 6.2e-11 42.1 0.0 0.0014 17.9 0.0 3.1 3 0 0 3 3 3 3 Protein tyrosine kinase APH PF01636.23 KFX98211.1 - 0.0016 18.4 0.1 0.052 13.5 0.0 2.7 2 1 1 3 3 3 1 Phosphotransferase enzyme family FTA2 PF13095.6 KFX98211.1 - 0.011 15.4 0.0 2.8 7.5 0.0 2.3 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Kinase-like PF14531.6 KFX98211.1 - 0.085 12.2 0.0 14 4.9 0.0 3.1 3 1 0 3 3 3 0 Kinase-like Kdo PF06293.14 KFX98211.1 - 0.097 12.0 0.0 0.16 11.3 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family LETM1 PF07766.13 KFX98226.1 - 1.9e-103 345.5 0.2 1.9e-103 345.5 0.2 1.6 2 0 0 2 2 2 1 LETM1-like protein SAP PF02037.27 KFX98226.1 - 0.0002 21.0 0.2 0.0036 17.0 0.0 3.0 4 0 0 4 4 4 1 SAP domain SKG6 PF08693.10 KFX98227.1 - 0.00039 19.8 0.7 0.00039 19.8 0.7 1.8 2 0 0 2 2 2 1 Transmembrane alpha-helix domain DUF5305 PF17231.2 KFX98227.1 - 0.02 14.3 0.4 0.031 13.7 0.4 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5305) DUF2207 PF09972.9 KFX98227.1 - 0.021 13.6 0.1 0.027 13.2 0.1 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Podoplanin PF05808.11 KFX98227.1 - 0.13 12.4 4.8 0.27 11.3 4.8 1.5 1 0 0 1 1 1 0 Podoplanin SOG2 PF10428.9 KFX98227.1 - 0.15 11.2 14.1 0.18 10.9 14.1 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein Apt1 PF10351.9 KFX98227.1 - 0.19 10.6 2.8 0.24 10.2 2.8 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain RIFIN PF02009.16 KFX98227.1 - 0.2 11.5 0.0 0.28 11.0 0.0 1.1 1 0 0 1 1 1 0 Rifin AJAP1_PANP_C PF15298.6 KFX98227.1 - 0.73 10.0 9.0 1.3 9.2 9.0 1.4 1 0 0 1 1 1 0 AJAP1/PANP C-terminus DUF1180 PF06679.12 KFX98227.1 - 0.97 9.8 18.2 68 3.8 0.0 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF1180) SPX PF03105.19 KFX98227.1 - 1.1 9.1 9.6 1.3 8.8 9.6 1.2 1 0 0 1 1 1 0 SPX domain Insulin_TMD PF17870.1 KFX98227.1 - 1.8 8.7 4.5 5.3 7.2 0.2 2.4 2 0 0 2 2 2 0 Insulin receptor trans-membrane segment PX PF00787.24 KFX98229.1 - 3.6e-21 75.3 0.7 6.1e-21 74.5 0.2 1.7 2 0 0 2 2 2 1 PX domain Vps5 PF09325.10 KFX98229.1 - 2.4e-09 37.1 8.7 0.00013 21.6 0.1 2.2 2 0 0 2 2 2 2 Vps5 C terminal like Occludin_ELL PF07303.13 KFX98229.1 - 0.044 14.5 0.3 2.8 8.7 0.0 3.2 2 1 1 3 3 3 0 Occludin homology domain Dynactin_p22 PF07426.11 KFX98229.1 - 0.066 13.1 0.1 5.2 6.9 0.0 2.3 2 0 0 2 2 2 0 Dynactin subunit p22 FlaC_arch PF05377.11 KFX98229.1 - 1.6 9.2 3.6 1.9 8.9 0.1 2.5 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) PhoLip_ATPase_C PF16212.5 KFX98230.1 - 4e-77 259.3 22.2 4e-77 259.3 22.2 1.7 2 0 0 2 2 2 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 KFX98230.1 - 4.8e-18 64.6 0.5 4.8e-18 64.6 0.5 1.8 2 0 0 2 2 2 1 Phospholipid-translocating ATPase N-terminal Cation_ATPase PF13246.6 KFX98230.1 - 1.9e-12 47.1 0.0 1.1e-11 44.6 0.0 2.2 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 KFX98230.1 - 2.3e-10 41.1 0.3 2.5e-06 27.9 0.0 3.0 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 KFX98230.1 - 0.0083 15.7 0.0 0.0083 15.7 0.0 2.7 3 0 0 3 3 3 1 E1-E2 ATPase Hydrolase_3 PF08282.12 KFX98230.1 - 0.012 15.4 0.4 0.032 14.0 0.4 1.7 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase IDO PF01231.18 KFX98259.1 - 8.4e-67 225.8 0.0 9.7e-67 225.6 0.0 1.0 1 0 0 1 1 1 1 Indoleamine 2,3-dioxygenase GCN5L1 PF06320.13 KFX98261.1 - 4.5e-10 39.7 0.2 1.1e-09 38.4 0.0 1.7 2 0 0 2 2 2 1 GCN5-like protein 1 (GCN5L1) PHD PF00628.29 KFX98261.1 - 0.0083 16.0 6.4 0.016 15.1 6.4 1.5 1 0 0 1 1 1 1 PHD-finger DOCK_N PF16172.5 KFX98262.1 - 1.5e-122 409.2 0.6 2.1e-122 408.7 0.6 1.2 1 0 0 1 1 1 1 DOCK N-terminus DOCK-C2 PF14429.6 KFX98262.1 - 2.3e-40 138.5 0.0 5.4e-40 137.3 0.0 1.7 1 0 0 1 1 1 1 C2 domain in Dock180 and Zizimin proteins DHR-2 PF06920.13 KFX98262.1 - 6.3e-34 117.5 2.5 4.8e-33 114.6 2.5 2.1 1 1 0 1 1 1 1 Dock homology region 2 SH3_9 PF14604.6 KFX98262.1 - 0.00024 20.9 0.0 0.0013 18.5 0.0 2.2 2 0 0 2 2 2 1 Variant SH3 domain SH3_1 PF00018.28 KFX98262.1 - 0.0004 19.9 0.0 0.00081 19.0 0.0 1.5 1 0 0 1 1 1 1 SH3 domain ADH_N PF08240.12 KFX98263.1 - 7.4e-09 35.5 0.0 2.2e-08 33.9 0.0 1.7 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 KFX98263.1 - 1e-08 36.3 0.0 2.6e-08 35.0 0.0 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 KFX98263.1 - 0.0036 17.3 0.0 0.0081 16.1 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Biotin_lipoyl PF00364.22 KFX98263.1 - 0.14 12.0 1.9 2.6 7.9 0.0 2.6 3 0 0 3 3 3 0 Biotin-requiring enzyme APH PF01636.23 KFX98267.1 - 0.00051 20.0 0.2 0.0009 19.2 0.2 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.20 KFX98267.1 - 0.0013 18.1 0.1 0.0019 17.5 0.1 1.1 1 0 0 1 1 1 1 Ecdysteroid kinase Choline_kinase PF01633.20 KFX98267.1 - 0.015 14.9 0.2 0.025 14.2 0.2 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase Zn_clus PF00172.18 KFX98268.1 - 0.00098 19.2 10.4 0.00098 19.2 10.4 2.1 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-C2H2 PF00096.26 KFX98268.1 - 0.0027 18.1 1.2 0.0086 16.5 1.2 1.9 1 0 0 1 1 1 1 Zinc finger, C2H2 type ABC2_membrane PF01061.24 KFX98269.1 - 1.8e-70 236.6 51.7 2e-40 138.5 15.7 2.4 2 0 0 2 2 2 2 ABC-2 type transporter ABC_tran PF00005.27 KFX98269.1 - 1.4e-28 100.1 0.0 1.7e-13 51.2 0.0 2.7 3 0 0 3 3 2 2 ABC transporter PDR_CDR PF06422.12 KFX98269.1 - 3.9e-16 58.7 4.5 6e-16 58.1 0.1 3.3 3 0 0 3 3 3 1 CDR ABC transporter AAA_21 PF13304.6 KFX98269.1 - 1.6e-05 24.9 0.1 0.032 14.0 0.0 2.5 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 KFX98269.1 - 0.00026 20.7 1.8 0.06 13.1 0.1 3.6 4 0 0 4 4 4 1 P-loop containing region of AAA domain SMC_N PF02463.19 KFX98269.1 - 0.00034 20.1 0.0 0.13 11.7 0.0 3.5 4 1 0 4 4 4 1 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 KFX98269.1 - 0.00071 19.9 0.2 0.058 13.7 0.0 3.3 3 1 0 3 3 3 1 AAA domain RsgA_GTPase PF03193.16 KFX98269.1 - 0.0024 17.8 0.4 0.0072 16.2 0.0 1.9 2 0 0 2 2 2 1 RsgA GTPase AAA_33 PF13671.6 KFX98269.1 - 0.0033 17.6 1.0 0.019 15.2 0.2 2.6 2 1 0 2 2 2 1 AAA domain AAA_25 PF13481.6 KFX98269.1 - 0.0037 16.9 0.4 0.043 13.4 0.1 2.6 3 0 0 3 3 3 1 AAA domain AAA_28 PF13521.6 KFX98269.1 - 0.0038 17.5 1.0 0.018 15.3 0.2 2.3 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 KFX98269.1 - 0.007 16.9 0.0 0.054 14.0 0.0 2.2 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.23 KFX98269.1 - 0.018 15.1 0.1 0.55 10.3 0.0 2.6 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_16 PF13191.6 KFX98269.1 - 0.019 15.4 0.9 0.84 10.0 0.3 2.9 2 1 0 2 2 2 0 AAA ATPase domain NACHT PF05729.12 KFX98269.1 - 0.041 13.8 0.1 0.47 10.4 0.1 2.4 2 0 0 2 2 2 0 NACHT domain IstB_IS21 PF01695.17 KFX98269.1 - 0.11 12.2 0.8 0.64 9.7 0.1 2.4 3 0 0 3 3 3 0 IstB-like ATP binding protein AAA_15 PF13175.6 KFX98269.1 - 0.12 12.1 0.0 11 5.6 0.0 2.4 2 0 0 2 2 2 0 AAA ATPase domain AAA_23 PF13476.6 KFX98269.1 - 0.12 12.8 0.2 0.32 11.5 0.2 1.7 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 KFX98269.1 - 0.13 11.9 0.6 1.2 8.8 0.1 2.3 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.22 KFX98269.1 - 0.25 10.5 0.5 3.4 6.8 0.1 2.4 2 0 0 2 2 2 0 NB-ARC domain DIOX_N PF14226.6 KFX98270.1 - 8.5e-23 81.3 0.2 1.4e-22 80.7 0.2 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 KFX98270.1 - 4.3e-17 62.5 0.0 6.7e-17 61.8 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily PORR PF11955.8 KFX98270.1 - 0.055 12.4 0.1 0.084 11.8 0.1 1.2 1 0 0 1 1 1 0 Plant organelle RNA recognition domain AMP-binding PF00501.28 KFX98271.1 - 1.6e-63 214.7 0.0 2.1e-63 214.4 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KFX98271.1 - 2e-08 35.1 0.0 5.1e-08 33.8 0.0 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Cas_VVA1548 PF09652.10 KFX98271.1 - 0.031 14.5 0.0 0.1 12.8 0.0 1.9 2 0 0 2 2 2 0 Putative CRISPR-associated protein (Cas_VVA1548) SIS_2 PF13580.6 KFX98271.1 - 0.13 12.2 0.0 0.26 11.3 0.0 1.4 1 0 0 1 1 1 0 SIS domain DAHP_synth_2 PF01474.16 KFX98272.1 - 5.6e-122 407.4 0.0 5.7e-70 236.0 0.0 2.0 1 1 1 2 2 2 2 Class-II DAHP synthetase family Methyltransf_23 PF13489.6 KFX98274.1 - 7.8e-12 45.3 0.0 1.1e-11 44.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KFX98274.1 - 7.8e-08 32.2 0.0 6.9e-07 29.2 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KFX98274.1 - 6.1e-07 30.1 0.0 3.9e-06 27.5 0.0 2.3 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 KFX98274.1 - 8.8e-07 29.5 0.0 3.4e-06 27.6 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 KFX98274.1 - 2.5e-05 25.0 0.0 5e-05 24.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain CheR PF01739.18 KFX98274.1 - 0.021 14.3 0.0 0.11 12.0 0.0 2.0 2 0 0 2 2 2 0 CheR methyltransferase, SAM binding domain FtsJ PF01728.19 KFX98274.1 - 0.056 13.6 0.1 0.22 11.6 0.0 1.9 2 1 0 2 2 2 0 FtsJ-like methyltransferase Ubie_methyltran PF01209.18 KFX98274.1 - 0.16 11.3 0.0 0.35 10.2 0.0 1.6 2 0 0 2 2 2 0 ubiE/COQ5 methyltransferase family YtxH PF12732.7 KFX98279.1 - 0.76 10.3 10.4 0.35 11.4 2.7 2.6 1 1 1 2 2 2 0 YtxH-like protein DUF883 PF05957.13 KFX98279.1 - 0.85 10.3 5.4 3.4 8.3 2.5 2.6 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) CsbD PF05532.12 KFX98279.1 - 1.9 8.5 20.3 1.5 8.8 12.8 3.8 2 2 0 2 2 2 0 CsbD-like MRG PF05712.13 KFX98281.1 - 1.7e-54 184.2 0.0 2.5e-54 183.6 0.0 1.2 1 0 0 1 1 1 1 MRG Tudor-knot PF11717.8 KFX98281.1 - 2.5e-08 33.6 1.4 5.7e-08 32.5 1.4 1.6 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain Chromo PF00385.24 KFX98281.1 - 0.015 15.2 1.2 0.042 13.8 1.2 1.8 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain RabGAP-TBC PF00566.18 KFX98283.1 - 6.2e-29 101.2 0.0 1.1e-28 100.4 0.0 1.4 1 0 0 1 1 1 1 Rab-GTPase-TBC domain SBE2 PF17076.5 KFX98283.1 - 2.7e-10 39.2 1.0 3.7e-10 38.7 1.0 1.1 1 0 0 1 1 1 1 SBE2, cell-wall formation Glyco_hydro_7 PF00840.20 KFX98284.1 - 1.3e-196 653.5 19.5 1.5e-196 653.3 19.5 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 7 CBM_21 PF03370.13 KFX98287.1 - 1.4e-33 115.4 2.8 2.5e-33 114.6 2.8 1.4 1 0 0 1 1 1 1 Carbohydrate/starch-binding module (family 21) CBM53 PF16760.5 KFX98287.1 - 1.4e-09 38.4 3.9 3e-09 37.3 3.9 1.5 1 0 0 1 1 1 1 Starch/carbohydrate-binding module (family 53) Acyltransferase PF01553.21 KFX98288.1 - 4.5e-32 110.5 0.0 7.8e-32 109.7 0.0 1.4 1 0 0 1 1 1 1 Acyltransferase SNO PF01174.19 KFX98290.1 - 1.5e-54 184.7 0.0 8.4e-45 152.9 0.0 2.0 1 1 0 2 2 2 2 SNO glutamine amidotransferase family GATase_3 PF07685.14 KFX98290.1 - 5.6e-10 39.1 0.0 5.2e-08 32.7 0.0 2.1 2 0 0 2 2 2 2 CobB/CobQ-like glutamine amidotransferase domain GATase PF00117.28 KFX98290.1 - 0.00057 19.7 0.0 0.89 9.3 0.0 2.1 2 0 0 2 2 2 2 Glutamine amidotransferase class-I DJ-1_PfpI PF01965.24 KFX98290.1 - 0.016 15.0 0.0 0.026 14.3 0.0 1.3 1 0 0 1 1 1 0 DJ-1/PfpI family Peptidase_S51 PF03575.17 KFX98290.1 - 0.019 14.6 0.0 0.028 14.1 0.0 1.2 1 0 0 1 1 1 0 Peptidase family S51 PX PF00787.24 KFX98291.1 - 1.9e-18 66.5 0.0 5.5e-18 65.0 0.0 1.8 1 0 0 1 1 1 1 PX domain Vps5 PF09325.10 KFX98291.1 - 5.4e-13 49.0 3.9 2.8e-07 30.3 0.2 2.2 2 0 0 2 2 2 2 Vps5 C terminal like BAR_3_WASP_bdg PF10456.9 KFX98291.1 - 0.034 13.6 0.0 4.7 6.6 0.0 2.2 2 0 0 2 2 2 0 WASP-binding domain of Sorting nexin protein Acyltransferase PF01553.21 KFX98292.1 - 2.2e-12 46.8 0.0 1.5e-11 44.1 0.0 2.2 2 1 0 2 2 2 1 Acyltransferase Hydrolase_4 PF12146.8 KFX98295.1 - 0.047 12.9 0.0 6.5 5.9 0.0 2.1 2 0 0 2 2 2 0 Serine aminopeptidase, S33 QRPTase_C PF01729.19 KFX98300.1 - 6.6e-35 120.4 0.0 7.4e-35 120.2 0.0 1.0 1 0 0 1 1 1 1 Quinolinate phosphoribosyl transferase, C-terminal domain PRAI PF00697.22 KFX98300.1 - 0.0024 17.7 0.1 0.0027 17.5 0.1 1.1 1 0 0 1 1 1 1 N-(5'phosphoribosyl)anthranilate (PRA) isomerase KDGP_aldolase PF07071.11 KFX98300.1 - 0.025 14.4 0.1 0.038 13.8 0.1 1.4 1 1 0 1 1 1 0 KDGP aldolase FMN_dh PF01070.18 KFX98300.1 - 0.07 12.2 0.2 0.074 12.1 0.2 1.2 1 0 0 1 1 1 0 FMN-dependent dehydrogenase ADH_N PF08240.12 KFX98301.1 - 2e-09 37.3 0.0 4.6e-09 36.1 0.0 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KFX98301.1 - 3.8e-06 26.9 0.8 3.8e-06 26.9 0.8 2.0 2 0 0 2 2 2 1 Zinc-binding dehydrogenase DUF3237 PF11578.8 KFX98302.1 - 2.6e-25 89.0 0.0 3.5e-25 88.6 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3237) DUF4470 PF14737.6 KFX98303.1 - 3e-22 78.6 0.1 7e-22 77.5 0.1 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4470) POP1 PF06978.11 KFX98304.1 - 5.1e-72 242.2 6.8 5.1e-72 242.2 6.8 1.7 2 0 0 2 2 2 1 Ribonucleases P/MRP protein subunit POP1 POPLD PF08170.12 KFX98304.1 - 6.3e-30 103.4 0.4 1.5e-29 102.1 0.4 1.7 1 0 0 1 1 1 1 POPLD (NUC188) domain DUF4596 PF15363.6 KFX98304.1 - 7.1 7.0 7.6 11 6.3 0.1 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4596) Redoxin PF08534.10 KFX98305.1 - 2.8e-33 114.7 0.0 3.2e-33 114.5 0.0 1.0 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.21 KFX98305.1 - 1e-11 44.8 0.0 1.3e-11 44.5 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family DUF1348 PF07080.11 KFX98306.1 - 4e-63 211.1 5.5 4.7e-63 210.9 5.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1348) SnoaL_2 PF12680.7 KFX98306.1 - 1.7e-08 35.1 1.2 2.2e-08 34.7 1.2 1.2 1 0 0 1 1 1 1 SnoaL-like domain DUF4440 PF14534.6 KFX98306.1 - 3.8e-06 27.3 0.1 5.3e-06 26.8 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4440) Y_phosphatase3 PF13350.6 KFX98307.1 - 9.1e-57 192.7 0.0 1.1e-56 192.4 0.0 1.1 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase PF00102.27 KFX98307.1 - 0.029 14.0 0.0 0.045 13.3 0.0 1.2 1 0 0 1 1 1 0 Protein-tyrosine phosphatase Y_phosphatase2 PF03162.13 KFX98307.1 - 0.061 12.9 0.0 0.096 12.3 0.0 1.3 1 0 0 1 1 1 0 Tyrosine phosphatase family PTPlike_phytase PF14566.6 KFX98307.1 - 0.17 12.0 0.0 0.33 11.0 0.0 1.4 1 0 0 1 1 1 0 Inositol hexakisphosphate Glyco_hydro_3_C PF01915.22 KFX98308.1 - 5.8e-47 160.3 0.0 1.2e-46 159.3 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 KFX98308.1 - 7.4e-41 140.6 0.0 1.1e-40 140.0 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 KFX98308.1 - 4.5e-22 77.9 0.0 1.1e-21 76.7 0.0 1.7 1 1 0 1 1 1 1 Fibronectin type III-like domain SNARE PF05739.19 KFX98308.1 - 0.048 13.7 3.4 0.096 12.7 3.4 1.4 1 0 0 1 1 1 0 SNARE domain Endotoxin_C2 PF18449.1 KFX98308.1 - 0.14 12.5 0.1 3.6 8.0 0.4 2.4 2 0 0 2 2 2 0 Delta endotoxin DUF4797 PF16051.5 KFX98308.1 - 1.1 9.2 3.0 0.66 10.0 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4797) Dala_Dala_lig_C PF07478.13 KFX98309.1 - 1e-24 87.2 0.0 1.6e-24 86.6 0.0 1.3 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus Glyco_hydro_16 PF00722.21 KFX98309.1 - 0.00015 21.3 0.5 0.00035 20.1 0.5 1.6 1 1 0 1 1 1 1 Glycosyl hydrolases family 16 ATP-grasp_3 PF02655.14 KFX98309.1 - 0.0017 18.4 0.0 0.0034 17.4 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain GARS_A PF01071.19 KFX98309.1 - 0.0029 17.4 0.0 0.0053 16.5 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain CPSase_L_D2 PF02786.17 KFX98309.1 - 0.005 16.4 0.0 0.014 14.9 0.0 1.7 1 1 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain DUF2235 PF09994.9 KFX98310.1 - 1.2e-85 287.4 0.3 1.8e-85 286.8 0.3 1.3 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) BAAT_C PF08840.11 KFX98310.1 - 0.099 12.5 0.0 0.22 11.4 0.0 1.7 1 1 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal Calpain_inhib PF00748.19 KFX98310.1 - 0.62 10.6 5.5 1.2 9.7 5.5 1.5 1 0 0 1 1 1 0 Calpain inhibitor An_peroxidase PF03098.15 KFX98311.1 - 7.6e-37 127.1 0.7 5.9e-10 38.3 0.1 4.0 2 1 2 4 4 4 4 Animal haem peroxidase p450 PF00067.22 KFX98311.1 - 1.1e-09 37.6 0.1 4.9e-08 32.1 0.0 2.2 2 0 0 2 2 2 2 Cytochrome P450 Cellulase PF00150.18 KFX98313.1 - 3.5e-56 190.7 0.1 4.4e-56 190.4 0.1 1.0 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) RGS PF00615.19 KFX98314.1 - 2.2e-09 37.6 0.0 3.4e-06 27.3 0.0 2.3 2 0 0 2 2 2 2 Regulator of G protein signaling domain MPC PF03650.13 KFX98315.1 - 7.7e-46 154.8 1.0 1e-45 154.4 1.0 1.1 1 0 0 1 1 1 1 Mitochondrial pyruvate carriers L51_S25_CI-B8 PF05047.16 KFX98316.1 - 6.1e-13 48.5 0.0 7.7e-13 48.2 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain EAF PF09816.9 KFX98317.1 - 1.4e-13 51.1 0.0 2.4e-13 50.3 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase II transcription elongation factor FAD_binding_7 PF03441.14 KFX98318.1 - 3.4e-38 131.2 0.1 5.3e-38 130.5 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.18 KFX98318.1 - 6.7e-19 68.5 0.0 1.3e-18 67.6 0.0 1.4 1 0 0 1 1 1 1 DNA photolyase 4HBT PF03061.22 KFX98319.1 - 2.6e-07 30.9 0.1 5.2e-07 29.9 0.1 1.5 1 0 0 1 1 1 1 Thioesterase superfamily MmgE_PrpD PF03972.14 KFX98322.1 - 1.2e-147 492.0 0.0 1.6e-147 491.6 0.0 1.0 1 0 0 1 1 1 1 MmgE/PrpD family TsaE PF02367.17 KFX98322.1 - 0.17 11.9 0.1 8.5 6.4 0.0 2.4 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Sulf_transp PF04143.14 KFX98324.1 - 1.8e-30 106.6 27.0 1.8e-30 106.6 27.0 1.8 1 1 1 2 2 2 1 Sulphur transport Fungal_trans PF04082.18 KFX98325.1 - 6.5e-21 74.6 0.0 1.5e-20 73.4 0.0 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KFX98325.1 - 4.3e-05 23.6 13.1 8.8e-05 22.5 13.1 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain R3H PF01424.22 KFX98327.1 - 3.5e-10 39.7 0.1 6.5e-10 38.9 0.1 1.5 1 0 0 1 1 1 1 R3H domain RRM_1 PF00076.22 KFX98327.1 - 3.6e-06 26.7 0.0 1.2e-05 25.1 0.0 1.9 2 1 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_2 PF04059.12 KFX98327.1 - 0.22 11.8 0.0 0.43 10.8 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif 2 Na_H_Exchanger PF00999.21 KFX98328.1 - 7.7e-21 74.3 3.1 1.2e-20 73.7 0.6 2.1 2 1 0 2 2 2 1 Sodium/hydrogen exchanger family YrhC PF14143.6 KFX98328.1 - 0.0034 17.5 0.9 0.0066 16.5 0.0 1.9 2 0 0 2 2 2 1 YrhC-like protein OPT PF03169.15 KFX98330.1 - 4.6e-173 577.2 57.6 5.3e-173 577.0 57.6 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein DAO PF01266.24 KFX98331.1 - 1e-29 104.3 0.0 1.3e-29 103.9 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KFX98331.1 - 3.7e-05 23.1 0.0 0.096 11.9 0.0 2.8 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KFX98331.1 - 0.00049 20.3 0.0 0.0011 19.1 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain GIDA PF01134.22 KFX98331.1 - 0.0011 18.1 0.1 0.51 9.3 0.1 2.1 2 0 0 2 2 2 2 Glucose inhibited division protein A FAD_binding_2 PF00890.24 KFX98331.1 - 0.0015 17.7 0.0 0.086 11.9 0.0 2.1 2 0 0 2 2 2 1 FAD binding domain Pyr_redox PF00070.27 KFX98331.1 - 0.011 16.3 0.1 0.12 13.0 0.0 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 KFX98331.1 - 0.014 14.7 0.0 0.045 13.0 0.0 1.8 2 0 0 2 2 2 0 FAD binding domain NAD_binding_9 PF13454.6 KFX98331.1 - 0.025 14.6 0.2 0.19 11.7 0.0 2.1 2 0 0 2 2 2 0 FAD-NAD(P)-binding ThiF PF00899.21 KFX98331.1 - 0.087 12.2 0.0 0.14 11.5 0.0 1.2 1 0 0 1 1 1 0 ThiF family NAD_binding_7 PF13241.6 KFX98331.1 - 0.12 12.8 0.0 0.26 11.8 0.0 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding Pyr_redox_3 PF13738.6 KFX98331.1 - 0.15 11.3 0.0 0.37 10.0 0.0 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 KFX98331.1 - 0.15 10.9 0.1 1.5 7.6 0.0 2.0 2 0 0 2 2 2 0 Tryptophan halogenase Fungal_trans_2 PF11951.8 KFX98332.1 - 2.9e-49 167.9 6.5 2.4e-24 85.9 4.7 2.2 1 1 1 2 2 2 2 Fungal specific transcription factor domain DAO PF01266.24 KFX98332.1 - 2.7e-40 139.0 0.1 4e-40 138.5 0.1 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KFX98332.1 - 1.3e-06 28.6 0.0 3e-06 27.4 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Zn_clus PF00172.18 KFX98332.1 - 1.4e-06 28.3 8.4 2.5e-06 27.5 8.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain FAD_binding_2 PF00890.24 KFX98332.1 - 7.4e-05 22.0 0.0 0.086 11.9 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain FAD_binding_3 PF01494.19 KFX98332.1 - 0.019 14.2 0.0 0.04 13.2 0.0 1.5 1 0 0 1 1 1 0 FAD binding domain Pyr_redox_2 PF07992.14 KFX98332.1 - 0.048 12.9 0.0 0.54 9.4 0.0 2.5 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KFX98332.1 - 0.053 14.1 0.0 0.38 11.3 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 KFX98332.1 - 0.079 11.8 0.0 9.1 5.0 0.0 2.2 2 0 0 2 2 2 0 Tryptophan halogenase DUF4780 PF16012.5 KFX98332.1 - 0.13 11.7 0.0 22 4.5 0.0 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4780) NAD_binding_9 PF13454.6 KFX98332.1 - 0.17 11.9 0.0 3.8 7.5 0.0 2.5 2 0 0 2 2 2 0 FAD-NAD(P)-binding Metallophos PF00149.28 KFX98336.1 - 3.6e-40 138.7 0.1 4.6e-40 138.3 0.1 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 KFX98336.1 - 3e-23 82.0 1.8 4.4e-23 81.5 1.0 1.7 2 0 0 2 2 2 1 Serine-threonine protein phosphatase N-terminal domain MT-A70 PF05063.14 KFX98339.1 - 2.2e-25 89.5 0.0 1.5e-17 64.1 0.0 2.3 1 1 0 2 2 2 2 MT-A70 Ribosomal_L23 PF00276.20 KFX98340.1 - 2.9e-13 50.0 0.0 5.6e-13 49.1 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L23 Pex2_Pex12 PF04757.14 KFX98341.1 - 1e-51 175.7 3.0 1.3e-51 175.4 3.0 1.1 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4_4 PF15227.6 KFX98341.1 - 0.00014 21.9 2.8 0.00025 21.1 2.8 1.4 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4_3 PF13920.6 KFX98341.1 - 0.0034 17.2 1.6 0.0055 16.5 1.6 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KFX98341.1 - 0.0049 16.9 2.4 0.0084 16.1 2.4 1.4 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 KFX98341.1 - 0.014 15.2 2.9 0.024 14.5 2.9 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KFX98341.1 - 0.018 15.4 3.2 0.031 14.6 3.2 1.3 1 0 0 1 1 1 0 Ring finger domain zf-C3HC4_2 PF13923.6 KFX98341.1 - 0.024 14.5 3.1 0.045 13.6 3.1 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Hamartin PF04388.12 KFX98342.1 - 1.2e-17 63.9 37.4 1.2e-17 63.9 37.4 4.2 1 1 0 2 2 2 1 Hamartin protein RACo_linker PF17650.1 KFX98342.1 - 0.0044 16.8 2.0 0.032 14.1 0.4 2.6 2 0 0 2 2 2 1 RACo linker region DUF5624 PF18538.1 KFX98342.1 - 0.065 13.3 0.4 0.29 11.2 0.4 2.1 1 0 0 1 1 1 0 Domain of unknown function (DUF5624) PilM_2 PF11104.8 KFX98342.1 - 1.6 7.7 9.2 0.033 13.2 0.5 2.1 2 0 0 2 2 2 0 Type IV pilus assembly protein PilM; Kdo PF06293.14 KFX98345.1 - 0.0002 20.8 0.3 0.00059 19.3 0.3 1.8 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.25 KFX98345.1 - 0.0021 17.5 0.1 0.0032 16.9 0.1 1.2 1 0 0 1 1 1 1 Protein kinase domain RIO1 PF01163.22 KFX98345.1 - 0.019 14.6 0.1 0.028 14.0 0.1 1.2 1 0 0 1 1 1 0 RIO1 family EcKinase PF02958.20 KFX98345.1 - 0.081 12.2 0.0 0.1 11.9 0.0 1.2 1 0 0 1 1 1 0 Ecdysteroid kinase WaaY PF06176.11 KFX98345.1 - 0.12 12.0 0.0 0.16 11.5 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide core biosynthesis protein (WaaY) CPSase_L_D2 PF02786.17 KFX98346.1 - 9.1e-113 374.9 0.2 1.8e-84 282.5 0.0 2.3 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_sm_chain PF00988.22 KFX98346.1 - 1.3e-46 157.6 0.0 2.6e-46 156.6 0.0 1.5 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain GATase PF00117.28 KFX98346.1 - 1.5e-45 155.3 0.0 3.4e-45 154.2 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase class-I OTCace_N PF02729.21 KFX98346.1 - 4.5e-44 150.0 0.0 1.2e-43 148.6 0.0 1.8 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain CPSase_L_D3 PF02787.19 KFX98346.1 - 7e-41 139.4 0.1 1.8e-40 138.1 0.1 1.8 1 0 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain OTCace PF00185.24 KFX98346.1 - 3.4e-29 101.9 0.0 7.7e-29 100.8 0.0 1.6 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain MGS PF02142.22 KFX98346.1 - 7.7e-21 74.1 0.0 4.4e-20 71.7 0.0 2.4 2 0 0 2 2 2 1 MGS-like domain Dala_Dala_lig_C PF07478.13 KFX98346.1 - 4.8e-17 62.2 0.8 1.4e-07 31.2 0.1 2.6 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus ATP-grasp PF02222.22 KFX98346.1 - 1.1e-14 54.4 0.1 8.7e-07 28.7 0.0 2.7 2 0 0 2 2 2 2 ATP-grasp domain ATPgrasp_Ter PF15632.6 KFX98346.1 - 3.7e-09 36.4 0.0 0.00059 19.6 0.0 3.0 3 0 0 3 3 3 2 ATP-grasp in the biosynthetic pathway with Ter operon Peptidase_C26 PF07722.13 KFX98346.1 - 2.8e-05 24.0 1.7 0.0018 18.1 0.6 2.8 2 1 0 2 2 2 1 Peptidase C26 ATP-grasp_3 PF02655.14 KFX98346.1 - 6.3e-05 23.1 0.4 0.18 11.9 0.1 2.7 2 0 0 2 2 2 2 ATP-grasp domain DJ-1_PfpI PF01965.24 KFX98346.1 - 0.00019 21.3 0.2 0.17 11.6 0.0 4.5 5 0 0 5 5 5 1 DJ-1/PfpI family GARS_A PF01071.19 KFX98346.1 - 0.00088 19.1 0.4 1.9 8.2 0.0 3.0 3 0 0 3 3 3 2 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain Ribonuclease_3 PF00636.26 KFX98347.1 - 1.2e-39 135.1 0.0 2.8e-19 69.7 0.0 3.1 2 0 0 2 2 2 2 Ribonuclease III domain Dicer_dimer PF03368.14 KFX98347.1 - 2.5e-24 85.2 0.2 5.4e-23 81.0 0.1 2.7 2 0 0 2 2 2 1 Dicer dimerisation domain Ribonucleas_3_3 PF14622.6 KFX98347.1 - 3.7e-21 75.6 0.0 2.9e-09 37.2 0.0 3.6 3 0 0 3 3 3 2 Ribonuclease-III-like Helicase_C PF00271.31 KFX98347.1 - 1.7e-16 60.5 0.1 5.1e-16 59.0 0.1 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KFX98347.1 - 8.1e-15 55.2 0.0 2.6e-14 53.6 0.0 1.9 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 KFX98347.1 - 2.5e-11 43.7 0.0 4.5e-11 42.8 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase dsrm PF00035.26 KFX98347.1 - 0.0025 18.5 0.0 1.3 9.8 0.0 2.9 2 0 0 2 2 2 2 Double-stranded RNA binding motif TAP42 PF04177.12 KFX98348.1 - 2e-101 339.3 0.0 2.3e-101 339.1 0.0 1.0 1 0 0 1 1 1 1 TAP42-like family RE_EcoO109I PF14511.6 KFX98348.1 - 0.0004 20.0 0.0 0.00064 19.4 0.0 1.3 1 0 0 1 1 1 1 Type II restriction endonuclease EcoO109I APG6_N PF17675.1 KFX98348.1 - 0.77 10.3 3.3 0.97 10.0 0.3 2.3 2 1 0 2 2 2 0 Apg6 coiled-coil region Glyoxalase PF00903.25 KFX98349.1 - 7.4e-08 32.6 0.3 9.9e-08 32.2 0.3 1.2 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 KFX98349.1 - 0.0014 18.9 0.2 0.0027 18.0 0.2 1.4 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_6 PF18029.1 KFX98349.1 - 0.052 14.3 0.1 0.082 13.7 0.1 1.5 1 1 0 1 1 1 0 Glyoxalase-like domain FAD_binding_3 PF01494.19 KFX98350.1 - 1.2e-22 80.7 0.0 1.1e-21 77.5 0.0 1.9 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.24 KFX98350.1 - 8.3e-11 42.1 2.9 0.00011 21.9 0.0 2.2 1 1 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KFX98350.1 - 3.8e-09 36.2 1.4 6.7e-05 22.3 0.3 2.2 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KFX98350.1 - 5.2e-08 32.4 0.4 1.6e-06 27.5 0.3 2.2 2 0 0 2 2 2 1 FAD binding domain Pyr_redox PF00070.27 KFX98350.1 - 5.3e-07 30.1 0.3 0.052 14.1 0.2 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 KFX98350.1 - 1.3e-06 28.0 0.3 2.8e-06 27.0 0.3 1.5 1 1 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.14 KFX98350.1 - 1.5e-05 24.0 0.8 0.00013 20.9 0.8 2.1 1 1 0 1 1 1 1 HI0933-like protein NAD_binding_8 PF13450.6 KFX98350.1 - 0.00011 22.3 0.3 0.00029 21.0 0.3 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.14 KFX98350.1 - 0.0009 18.2 1.2 0.016 14.0 0.1 2.5 2 1 0 3 3 3 1 Tryptophan halogenase GIDA PF01134.22 KFX98350.1 - 0.0025 16.9 0.9 0.0038 16.4 0.9 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A SE PF08491.10 KFX98350.1 - 0.04 13.0 0.0 0.27 10.2 0.0 1.9 2 0 0 2 2 2 0 Squalene epoxidase Thi4 PF01946.17 KFX98350.1 - 0.041 13.1 0.2 0.071 12.3 0.2 1.3 1 0 0 1 1 1 0 Thi4 family Pyr_redox_3 PF13738.6 KFX98350.1 - 0.12 11.6 0.0 0.25 10.6 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KFX98350.1 - 0.14 11.1 0.3 0.59 9.1 0.3 1.8 2 0 0 2 2 2 0 Lycopene cyclase protein 3HCDH_N PF02737.18 KFX98350.1 - 0.19 11.6 0.0 0.32 10.9 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Ank_2 PF12796.7 KFX98351.1 - 1.5e-21 76.7 0.8 5.6e-11 42.9 0.1 3.5 2 1 1 3 3 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KFX98351.1 - 1.2e-19 70.4 0.1 3.7e-09 36.9 0.0 3.3 3 0 0 3 3 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 KFX98351.1 - 1e-18 67.1 2.1 5.3e-10 39.3 0.1 3.1 3 0 0 3 3 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFX98351.1 - 1.5e-13 49.5 0.6 0.00055 20.2 0.0 5.9 6 0 0 6 6 4 3 Ankyrin repeat Ank PF00023.30 KFX98351.1 - 3.5e-13 49.3 0.9 3.4e-06 27.2 0.0 5.8 7 0 0 7 7 4 2 Ankyrin repeat NACHT PF05729.12 KFX98351.1 - 5.5e-10 39.4 0.2 0.026 14.4 0.0 3.7 3 0 0 3 3 3 2 NACHT domain RNA_helicase PF00910.22 KFX98351.1 - 6.9e-07 29.6 0.2 0.013 15.9 0.0 3.0 3 0 0 3 3 3 2 RNA helicase AAA_22 PF13401.6 KFX98351.1 - 5e-05 23.6 0.0 0.0012 19.1 0.1 3.0 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.6 KFX98351.1 - 0.00016 22.1 0.0 0.56 10.6 0.0 3.2 2 1 0 2 2 2 2 AAA ATPase domain DUF676 PF05057.14 KFX98351.1 - 0.00019 21.0 0.0 0.00044 19.8 0.0 1.6 1 0 0 1 1 1 1 Putative serine esterase (DUF676) AAA PF00004.29 KFX98351.1 - 0.0003 21.2 0.0 0.87 10.0 0.0 3.9 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 KFX98351.1 - 0.00039 20.6 0.0 0.0033 17.6 0.0 2.4 2 0 0 2 2 2 1 AAA domain APS_kinase PF01583.20 KFX98351.1 - 0.001 19.0 0.0 0.073 13.0 0.0 2.6 2 0 0 2 2 2 1 Adenylylsulphate kinase Abhydrolase_6 PF12697.7 KFX98351.1 - 0.0011 19.6 0.0 0.0023 18.6 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family AAA_18 PF13238.6 KFX98351.1 - 0.0015 19.0 0.0 0.0094 16.5 0.0 2.4 2 0 0 2 2 1 1 AAA domain Hydrolase_4 PF12146.8 KFX98351.1 - 0.0022 17.3 0.0 0.0047 16.2 0.0 1.5 1 0 0 1 1 1 1 Serine aminopeptidase, S33 TsaE PF02367.17 KFX98351.1 - 0.0034 17.4 0.0 1.5 8.8 0.0 2.5 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE ABC_tran PF00005.27 KFX98351.1 - 0.017 15.7 0.0 0.1 13.1 0.0 2.2 2 0 0 2 2 2 0 ABC transporter DUF5385 PF17359.2 KFX98351.1 - 0.034 13.7 0.0 2.1 7.9 0.0 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF5385) NB-ARC PF00931.22 KFX98351.1 - 0.047 12.9 0.0 0.63 9.2 0.0 2.3 2 0 0 2 2 2 0 NB-ARC domain PGAP1 PF07819.13 KFX98351.1 - 0.12 12.1 0.0 0.26 11.0 0.0 1.6 1 0 0 1 1 1 0 PGAP1-like protein NTPase_1 PF03266.15 KFX98351.1 - 0.12 12.3 0.1 0.99 9.3 0.0 2.5 3 0 0 3 3 3 0 NTPase Zeta_toxin PF06414.12 KFX98351.1 - 0.12 11.6 0.0 0.58 9.4 0.0 2.0 2 0 0 2 2 2 0 Zeta toxin KTI12 PF08433.10 KFX98351.1 - 0.14 11.6 0.1 0.56 9.6 0.0 2.0 2 0 0 2 2 2 0 Chromatin associated protein KTI12 Ploopntkinase3 PF18751.1 KFX98351.1 - 0.17 11.8 0.0 2.1 8.3 0.0 2.3 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 STE3 PF02076.15 KFX98366.1 - 4.5e-14 52.4 1.4 5.8e-14 52.0 1.4 1.1 1 0 0 1 1 1 1 Pheromone A receptor PAPS_reduct PF01507.19 KFX98367.1 - 3.7e-22 79.2 0.0 9e-20 71.4 0.0 2.2 1 1 1 2 2 2 2 Phosphoadenosine phosphosulfate reductase family DUF202 PF02656.15 KFX98368.1 - 1e-16 61.1 1.5 6.7e-16 58.5 0.0 2.1 1 1 1 2 2 2 1 Domain of unknown function (DUF202) COX4_pro_2 PF07835.12 KFX98368.1 - 0.03 14.4 1.8 0.51 10.5 0.0 2.4 2 0 0 2 2 2 0 Bacterial aa3 type cytochrome c oxidase subunit IV DUF5336 PF17270.2 KFX98368.1 - 0.11 12.1 0.6 0.16 11.6 0.5 1.3 1 1 0 1 1 1 0 Family of unknown function (DUF5336) Oxidored_q3 PF00499.20 KFX98368.1 - 0.12 12.1 3.6 0.52 10.0 3.6 1.8 1 1 0 1 1 1 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 MatE PF01554.18 KFX98369.1 - 1.7e-58 196.9 28.6 1.6e-32 112.4 10.4 2.3 2 0 0 2 2 2 2 MatE Polysacc_synt_C PF14667.6 KFX98369.1 - 0.0006 19.9 8.5 0.0006 19.9 8.5 3.6 2 1 0 3 3 3 1 Polysaccharide biosynthesis C-terminal domain MFS_1 PF07690.16 KFX98370.1 - 1.8e-19 69.9 20.2 2.2e-19 69.6 20.2 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF4500 PF14937.6 KFX98370.1 - 0.015 15.3 0.1 0.035 14.1 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4500) DUF1772 PF08592.11 KFX98370.1 - 0.022 15.1 0.2 0.3 11.4 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF1772) DUF2417 PF10329.9 KFX98370.1 - 1.4 8.3 7.5 1.6 8.1 2.9 2.8 3 0 0 3 3 3 0 Region of unknown function (DUF2417) UPF0242 PF06785.11 KFX98370.1 - 5.9 6.9 7.4 26 4.8 0.8 3.3 3 1 1 4 4 4 0 Uncharacterised protein family (UPF0242) N-terminus Sulfatase PF00884.23 KFX98371.1 - 3.3e-43 148.2 0.0 2.5e-41 142.1 0.0 2.5 1 1 0 1 1 1 1 Sulfatase DUF4976 PF16347.5 KFX98371.1 - 0.0005 20.3 3.4 0.0072 16.6 0.9 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF4976) DUF229 PF02995.17 KFX98371.1 - 0.034 12.7 0.0 0.056 12.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF229) Thioredox_DsbH PF03190.15 KFX98371.1 - 0.092 12.7 0.0 0.18 11.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF255 CDC45 PF02724.14 KFX98371.1 - 0.11 10.8 5.2 0.16 10.2 5.2 1.2 1 0 0 1 1 1 0 CDC45-like protein SDA1 PF05285.12 KFX98371.1 - 0.13 11.7 11.0 0.2 11.1 11.0 1.2 1 0 0 1 1 1 0 SDA1 Peroxin-3 PF04882.12 KFX98371.1 - 0.33 9.9 4.0 1.8 7.5 0.0 2.2 2 0 0 2 2 2 0 Peroxin-3 Zip PF02535.22 KFX98371.1 - 0.61 9.3 1.8 0.93 8.6 1.8 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter SAPS PF04499.15 KFX98371.1 - 0.67 8.7 6.1 1 8.1 6.1 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Nop14 PF04147.12 KFX98371.1 - 4.2 5.4 11.6 6 4.9 11.6 1.1 1 0 0 1 1 1 0 Nop14-like family Macoilin PF09726.9 KFX98371.1 - 8 4.9 5.6 12 4.3 5.6 1.2 1 0 0 1 1 1 0 Macoilin family Beta-lactamase PF00144.24 KFX98372.1 - 1e-31 110.4 0.8 2.6e-31 109.1 0.8 1.5 1 1 0 1 1 1 1 Beta-lactamase APH PF01636.23 KFX98373.1 - 4.9e-08 33.2 0.0 1.8e-06 28.1 0.0 3.0 2 1 0 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KFX98373.1 - 0.0083 15.7 0.0 0.016 14.8 0.0 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase Peptidase_M49 PF03571.15 KFX98374.1 - 1e-209 697.5 0.0 1.3e-209 697.2 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M49 2C_adapt PF08793.10 KFX98374.1 - 0.13 12.5 0.3 2 8.6 0.2 2.4 2 0 0 2 2 2 0 2-cysteine adaptor domain TPR_12 PF13424.6 KFX98376.1 - 1.4e-26 92.6 1.5 1.1e-10 41.7 0.0 5.0 2 2 3 5 5 5 4 Tetratricopeptide repeat TPR_10 PF13374.6 KFX98376.1 - 5.9e-14 51.4 5.0 0.00046 20.0 0.1 5.9 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_1 PF00515.28 KFX98376.1 - 1.4e-09 37.4 0.5 0.00011 21.8 0.0 5.7 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_2 PF07719.17 KFX98376.1 - 1.4e-09 37.4 3.8 0.63 10.3 0.0 6.7 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_8 PF13181.6 KFX98376.1 - 1.7e-09 37.1 7.9 0.0046 17.1 0.1 6.0 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_MalT PF17874.1 KFX98376.1 - 4.6e-07 29.5 0.0 0.00012 21.6 0.0 2.8 1 1 1 3 3 3 1 MalT-like TPR region TPR_7 PF13176.6 KFX98376.1 - 6.3e-07 29.0 0.0 0.022 14.7 0.1 5.2 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_14 PF13428.6 KFX98376.1 - 5.2e-05 23.7 7.6 1.9 9.5 0.2 6.6 6 1 1 7 7 7 1 Tetratricopeptide repeat PPR PF01535.20 KFX98376.1 - 0.00025 21.1 0.1 0.61 10.5 0.0 4.1 5 0 0 5 5 5 1 PPR repeat TPR_16 PF13432.6 KFX98376.1 - 0.0012 19.4 4.7 0.35 11.5 0.3 4.9 5 2 0 5 5 4 1 Tetratricopeptide repeat TPR_19 PF14559.6 KFX98376.1 - 0.0081 16.7 0.5 0.26 11.8 0.0 4.5 4 1 3 7 7 5 2 Tetratricopeptide repeat TPR_4 PF07721.14 KFX98376.1 - 0.025 15.2 0.9 4.3 8.2 0.1 4.5 5 0 0 5 5 4 0 Tetratricopeptide repeat TPR_17 PF13431.6 KFX98376.1 - 0.12 12.8 1.3 7.8 7.1 0.0 3.9 4 0 0 4 4 3 0 Tetratricopeptide repeat NAGidase PF07555.13 KFX98377.1 - 4.6e-97 324.9 0.2 8.2e-97 324.1 0.2 1.4 2 0 0 2 2 2 1 beta-N-acetylglucosaminidase Glyco_hydro_20b PF02838.15 KFX98377.1 - 4.1e-19 69.6 0.1 7.5e-19 68.7 0.1 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, domain 2 Glyco_hydro_67N PF03648.14 KFX98377.1 - 0.0003 21.1 0.1 0.00069 19.9 0.1 1.6 1 0 0 1 1 1 1 Glycosyl hydrolase family 67 N-terminus Arb1 PF09692.10 KFX98378.1 - 2.9e-138 461.4 0.0 3.7e-138 461.1 0.0 1.1 1 0 0 1 1 1 1 Argonaute siRNA chaperone (ARC) complex subunit Arb1 IPK PF03770.16 KFX98379.1 - 2.3e-53 181.0 0.0 2.8e-53 180.7 0.0 1.1 1 0 0 1 1 1 1 Inositol polyphosphate kinase ADH_zinc_N PF00107.26 KFX98398.1 - 4e-23 81.8 2.0 7.3e-23 81.0 2.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KFX98398.1 - 1.6e-17 63.3 0.9 3e-17 62.5 0.9 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 KFX98398.1 - 2.7e-07 31.7 1.3 3.1e-07 31.5 0.3 1.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Sod_Fe_C PF02777.18 KFX98399.1 - 1.9e-16 60.1 0.0 5.3e-07 29.7 0.1 2.3 2 0 0 2 2 2 2 Iron/manganese superoxide dismutases, C-terminal domain MOSC PF03473.17 KFX98400.1 - 2.6e-35 121.3 0.0 4.6e-35 120.5 0.0 1.4 1 0 0 1 1 1 1 MOSC domain Aminotran_5 PF00266.19 KFX98400.1 - 7.8e-25 87.6 0.0 1.5e-24 86.6 0.0 1.5 1 1 0 1 1 1 1 Aminotransferase class-V MOSC_N PF03476.16 KFX98400.1 - 3.6e-19 68.8 0.0 8.6e-19 67.6 0.0 1.7 1 0 0 1 1 1 1 MOSC N-terminal beta barrel domain NAD_binding_8 PF13450.6 KFX98403.1 - 0.0016 18.6 0.1 0.0059 16.8 0.0 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KFX98403.1 - 0.0043 16.7 0.6 0.0064 16.1 0.1 1.5 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KFX98403.1 - 0.039 13.2 0.0 0.05 12.8 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 KFX98403.1 - 0.04 13.2 0.1 0.063 12.6 0.1 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Trp_halogenase PF04820.14 KFX98403.1 - 0.067 12.0 0.2 0.091 11.6 0.2 1.2 1 0 0 1 1 1 0 Tryptophan halogenase Mito_carr PF00153.27 KFX98406.1 - 9.4e-55 182.5 3.8 1.7e-19 69.5 0.2 3.4 3 0 0 3 3 3 3 Mitochondrial carrier protein Sec34 PF04136.15 KFX98406.1 - 1.5e-49 167.7 3.3 3.3e-49 166.6 3.3 1.6 1 0 0 1 1 1 1 Sec34-like family Phasin_2 PF09361.10 KFX98406.1 - 1.5 9.1 4.0 2 8.7 0.5 2.8 3 0 0 3 3 3 0 Phasin protein RCC1 PF00415.18 KFX98407.1 - 7.9e-26 90.4 9.0 5.1e-06 27.0 0.0 7.8 7 2 0 7 7 7 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 KFX98407.1 - 2.5e-12 46.2 16.1 1.5e-07 31.0 0.4 6.3 6 0 0 6 6 6 3 Regulator of chromosome condensation (RCC1) repeat DDHD PF02862.17 KFX98408.1 - 0.03 14.5 7.8 0.043 14.0 7.8 1.3 1 0 0 1 1 1 0 DDHD domain CDC45 PF02724.14 KFX98408.1 - 0.14 10.4 23.0 0.21 9.8 23.0 1.3 1 0 0 1 1 1 0 CDC45-like protein TMEM174 PF15029.6 KFX98408.1 - 0.23 11.1 4.2 0.38 10.4 4.2 1.3 1 0 0 1 1 1 0 Transmembrane protein 174 DUF5427 PF10310.9 KFX98408.1 - 0.29 10.0 25.7 0.39 9.6 25.7 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5427) CRT10 PF08728.10 KFX98408.1 - 0.39 8.8 10.3 0.44 8.6 10.3 1.0 1 0 0 1 1 1 0 CRT10 Borrelia_P83 PF05262.11 KFX98408.1 - 0.74 8.2 21.0 0.91 7.9 21.0 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein LAP1C PF05609.12 KFX98408.1 - 0.97 8.4 18.4 1.3 8.0 18.4 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) SOBP PF15279.6 KFX98408.1 - 1.8 9.1 10.8 2.3 8.7 10.8 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein RR_TM4-6 PF06459.12 KFX98408.1 - 1.8 8.3 23.4 2.8 7.7 23.4 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 AAA_11 PF13086.6 KFX98408.1 - 2.1 8.1 16.4 3 7.5 16.4 1.3 1 0 0 1 1 1 0 AAA domain Presenilin PF01080.17 KFX98408.1 - 2.4 6.8 21.0 3.2 6.4 21.0 1.1 1 0 0 1 1 1 0 Presenilin DUF913 PF06025.12 KFX98408.1 - 5 6.0 9.6 7.5 5.4 9.6 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) DUF4407 PF14362.6 KFX98408.1 - 6.3 6.1 17.2 11 5.3 17.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) PPP4R2 PF09184.11 KFX98408.1 - 6.7 6.2 16.9 9.7 5.7 16.9 1.2 1 0 0 1 1 1 0 PPP4R2 Zip PF02535.22 KFX98408.1 - 8 5.6 12.3 11 5.2 12.3 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter LMBR1 PF04791.16 KFX98408.1 - 8 5.2 11.7 10 4.9 11.7 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein eIF-3_zeta PF05091.12 KFX98408.1 - 9.4 5.1 24.9 13 4.6 24.9 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Hid1 PF12722.7 KFX98408.1 - 9.5 4.2 20.8 13 3.8 20.8 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DEAD PF00270.29 KFX98410.1 - 1.6e-43 148.5 0.0 2.4e-43 147.9 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KFX98410.1 - 9.7e-28 96.7 1.0 6.4e-27 94.1 0.4 2.3 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 KFX98410.1 - 5.4e-05 23.3 0.0 0.0001 22.3 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit CMS1 PF14617.6 KFX98410.1 - 0.12 11.7 0.0 0.26 10.6 0.0 1.5 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit TFIIA PF03153.13 KFX98410.1 - 8.6 6.2 20.0 13 5.7 20.0 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit CoA_trans PF01144.23 KFX98411.1 - 5.1e-99 330.0 2.2 1.9e-62 210.5 0.0 2.1 2 0 0 2 2 2 2 Coenzyme A transferase Nrap_D5 PF17406.2 KFX98412.1 - 8.7e-61 204.4 0.1 1.5e-60 203.7 0.1 1.4 1 0 0 1 1 1 1 Nrap protein PAP/OAS1-like domain 5 Nrap_D4 PF17405.2 KFX98412.1 - 5.8e-60 202.3 0.1 1.3e-59 201.2 0.1 1.5 1 0 0 1 1 1 1 Nrap protein nucleotidyltransferase domain 4 Nrap_D2 PF17403.2 KFX98412.1 - 4.2e-51 172.7 0.0 2e-47 160.8 0.0 2.4 2 0 0 2 2 2 2 Nrap protein PAP/OAS-like domain Nrap_D3 PF17404.2 KFX98412.1 - 3.4e-48 163.7 0.0 6.5e-48 162.8 0.0 1.5 1 0 0 1 1 1 1 Nrap protein domain 3 Nrap PF03813.14 KFX98412.1 - 6.8e-48 162.6 0.0 1.3e-47 161.7 0.0 1.5 1 0 0 1 1 1 1 Nrap protein domain 1 Nrap_D6 PF17407.2 KFX98412.1 - 9.4e-34 116.5 0.0 2.7e-33 115.1 0.0 1.9 1 0 0 1 1 1 1 Nrap protein domain 6 Cys_Met_Meta_PP PF01053.20 KFX98413.1 - 4.5e-27 94.6 0.0 7.4e-27 93.9 0.0 1.3 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme SMC_N PF02463.19 KFX98413.1 - 1.2e-23 83.7 0.9 2.1e-23 82.9 0.9 1.4 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 KFX98413.1 - 7.6e-15 55.9 24.2 7.6e-15 55.9 24.2 5.1 2 2 2 4 4 4 2 AAA domain AAA_15 PF13175.6 KFX98413.1 - 4.2e-12 46.5 12.4 4.2e-12 46.5 12.4 3.0 3 1 1 4 4 4 1 AAA ATPase domain AAA_21 PF13304.6 KFX98413.1 - 1.9e-06 27.9 3.0 6.9e-05 22.8 0.6 2.9 3 0 0 3 3 3 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 KFX98413.1 - 0.0002 21.1 0.3 0.00069 19.3 0.1 1.9 2 0 0 2 2 2 1 P-loop containing region of AAA domain SMC_hinge PF06470.13 KFX98413.1 - 0.00039 20.7 0.0 0.0017 18.7 0.0 2.1 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain Baculo_PEP_C PF04513.12 KFX98413.1 - 2 8.5 8.0 2.8 8.0 0.4 3.8 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus adh_short PF00106.25 KFX98415.1 - 6.5e-05 22.5 0.5 0.00015 21.3 0.0 1.8 2 0 0 2 2 2 1 short chain dehydrogenase F-protein PF00469.20 KFX98415.1 - 0.018 14.7 0.0 0.021 14.4 0.0 1.0 1 0 0 1 1 1 0 Negative factor, (F-Protein) or Nef Med3 PF11593.8 KFX98415.1 - 0.055 12.7 6.4 0.054 12.7 6.4 1.0 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Val_tRNA-synt_C PF10458.9 KFX98415.1 - 0.062 13.6 1.9 0.14 12.5 1.9 1.4 1 0 0 1 1 1 0 Valyl tRNA synthetase tRNA binding arm LacAB_rpiB PF02502.18 KFX98416.1 - 2e-44 151.0 0.0 2.3e-44 150.8 0.0 1.0 1 0 0 1 1 1 1 Ribose/Galactose Isomerase Gly_rich_SFCGS PF14272.6 KFX98416.1 - 0.042 13.9 0.0 0.064 13.3 0.0 1.2 1 0 0 1 1 1 0 Glycine-rich SFCGS Homeobox_KN PF05920.11 KFX98420.1 - 9.3e-14 51.1 0.2 2.4e-13 49.7 0.2 1.8 1 0 0 1 1 1 1 Homeobox KN domain Homeodomain PF00046.29 KFX98420.1 - 1.9e-06 27.6 0.5 5.6e-06 26.1 0.5 1.8 1 0 0 1 1 1 1 Homeodomain zf-C2H2_4 PF13894.6 KFX98420.1 - 0.0059 17.3 21.9 0.023 15.5 2.4 4.7 4 0 0 4 4 4 2 C2H2-type zinc finger zf-C2H2 PF00096.26 KFX98420.1 - 0.013 15.9 21.4 0.56 10.8 0.2 4.5 4 0 0 4 4 4 0 Zinc finger, C2H2 type zf-met PF12874.7 KFX98420.1 - 0.19 12.2 9.9 20 5.8 1.0 3.9 3 0 0 3 3 3 0 Zinc-finger of C2H2 type DUF4124 PF13511.6 KFX98420.1 - 2.6 8.4 4.7 5.4 7.4 0.3 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4124) GTP_EFTU PF00009.27 KFX98422.1 - 4.6e-47 160.1 0.0 8.2e-47 159.3 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_II PF14492.6 KFX98422.1 - 1.9e-26 91.9 0.1 6.1e-26 90.3 0.0 1.9 2 0 0 2 2 2 1 Elongation Factor G, domain II EFG_C PF00679.24 KFX98422.1 - 4.9e-17 61.8 0.1 5.2e-09 36.0 0.0 2.7 2 0 0 2 2 2 2 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 KFX98422.1 - 1.6e-10 41.2 0.0 5.4e-10 39.5 0.0 2.0 1 0 0 1 1 1 1 Elongation factor Tu domain 2 RF3_C PF16658.5 KFX98422.1 - 0.00013 21.7 0.0 0.00029 20.7 0.0 1.5 1 0 0 1 1 1 1 Class II release factor RF3, C-terminal domain EFG_IV PF03764.18 KFX98422.1 - 0.015 15.1 0.0 0.16 11.7 0.0 2.3 2 0 0 2 2 2 0 Elongation factor G, domain IV PX PF00787.24 KFX98423.1 - 5.9e-10 39.1 0.0 1.2e-09 38.2 0.0 1.5 1 0 0 1 1 1 1 PX domain Vps5 PF09325.10 KFX98423.1 - 1.6e-09 37.7 0.6 2.6e-09 37.0 0.6 1.3 1 0 0 1 1 1 1 Vps5 C terminal like CCT_2 PF09425.10 KFX98423.1 - 0.28 11.1 4.6 9.4 6.2 0.1 2.9 2 0 0 2 2 2 0 Divergent CCT motif SAP PF02037.27 KFX98424.1 - 6.7e-13 48.1 0.2 1.5e-12 46.9 0.2 1.7 1 0 0 1 1 1 1 SAP domain Pribosyltran_N PF13793.6 KFX98425.1 - 5.6e-42 142.4 0.1 5.2e-40 136.0 0.0 2.4 2 0 0 2 2 2 2 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.6 KFX98425.1 - 3.3e-33 115.3 0.0 3.6e-28 98.9 0.0 2.2 2 0 0 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.27 KFX98425.1 - 1.6e-07 31.0 0.0 8e-05 22.2 0.0 2.4 2 0 0 2 2 2 2 Phosphoribosyl transferase domain XPG_I_2 PF12813.7 KFX98426.1 - 1.6e-59 201.4 0.0 2.4e-59 200.8 0.0 1.2 1 0 0 1 1 1 1 XPG domain containing OmdA PF13376.6 KFX98426.1 - 0.011 15.7 0.0 0.35 10.9 0.1 2.6 2 0 0 2 2 2 0 Bacteriocin-protection, YdeI or OmpD-Associated CREPT PF16566.5 KFX98426.1 - 0.013 15.7 1.4 0.08 13.1 0.1 2.4 2 0 0 2 2 2 0 Cell-cycle alteration and expression-elevated protein in tumour XPG_I PF00867.18 KFX98426.1 - 0.12 12.8 0.1 0.38 11.1 0.0 1.9 2 0 0 2 2 2 0 XPG I-region DUF383 PF04063.14 KFX98428.1 - 4.1e-68 228.8 0.1 1.1e-67 227.5 0.0 1.8 3 0 0 3 3 3 1 Domain of unknown function (DUF383) DUF384 PF04064.13 KFX98428.1 - 5.3e-22 77.4 1.9 1.4e-21 76.1 1.9 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF384) Mic1 PF07035.12 KFX98428.1 - 0.023 14.4 0.2 0.052 13.3 0.2 1.6 1 0 0 1 1 1 0 Colon cancer-associated protein Mic1-like Thi4 PF01946.17 KFX98431.1 - 5.9e-116 385.7 0.0 7e-116 385.5 0.0 1.1 1 0 0 1 1 1 1 Thi4 family DAO PF01266.24 KFX98431.1 - 2.1e-06 27.6 0.0 3.1e-06 27.0 0.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KFX98431.1 - 3.9e-05 23.8 0.2 0.00012 22.3 0.2 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 KFX98431.1 - 0.00014 21.1 0.1 0.00022 20.4 0.1 1.4 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_2 PF07992.14 KFX98431.1 - 0.0012 18.2 0.0 0.0017 17.6 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KFX98431.1 - 0.0014 18.6 0.1 0.0046 17.0 0.0 1.9 2 0 0 2 2 2 1 FAD-NAD(P)-binding FAD_binding_2 PF00890.24 KFX98431.1 - 0.014 14.5 0.6 0.028 13.5 0.6 1.5 1 0 0 1 1 1 0 FAD binding domain FAD_oxidored PF12831.7 KFX98431.1 - 0.014 14.7 0.0 0.019 14.3 0.0 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase Trp_halogenase PF04820.14 KFX98431.1 - 0.064 12.1 0.2 0.091 11.6 0.2 1.2 1 0 0 1 1 1 0 Tryptophan halogenase Pyr_redox_3 PF13738.6 KFX98431.1 - 0.075 12.3 0.0 0.12 11.6 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 KFX98431.1 - 0.094 11.9 0.1 0.14 11.4 0.1 1.2 1 0 0 1 1 1 0 FAD binding domain HI0933_like PF03486.14 KFX98431.1 - 0.14 10.9 0.6 0.2 10.3 0.6 1.2 1 0 0 1 1 1 0 HI0933-like protein K_oxygenase PF13434.6 KFX98431.1 - 0.21 10.7 0.0 0.31 10.1 0.0 1.2 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) Asparaginase PF00710.20 KFX98432.1 - 1.7e-57 194.1 0.0 2.5e-57 193.5 0.0 1.3 1 0 0 1 1 1 1 Asparaginase, N-terminal Asparaginase_C PF17763.1 KFX98432.1 - 2.4e-24 85.8 0.0 4.5e-24 84.9 0.0 1.5 1 0 0 1 1 1 1 Glutaminase/Asparaginase C-terminal domain Ank_2 PF12796.7 KFX98432.1 - 9.3e-12 45.4 2.4 4.8e-06 27.1 0.1 2.5 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KFX98432.1 - 8.2e-07 29.5 0.0 3.1e-06 27.6 0.0 2.1 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 KFX98432.1 - 2.9e-06 27.5 0.8 6.7e-06 26.3 0.3 2.0 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFX98432.1 - 1.2e-05 25.2 0.2 0.00083 19.6 0.0 3.6 3 1 0 3 3 3 1 Ankyrin repeat Ank PF00023.30 KFX98432.1 - 4.1e-05 23.8 0.1 0.00075 19.8 0.0 2.9 2 0 0 2 2 2 1 Ankyrin repeat WD40 PF00400.32 KFX98433.1 - 5.4e-20 71.3 3.5 0.00014 22.6 0.0 7.2 7 0 0 7 7 7 6 WD domain, G-beta repeat Fungal_trans PF04082.18 KFX98434.1 - 7e-17 61.3 0.3 1.1e-16 60.7 0.3 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KFX98434.1 - 1.2e-06 28.5 8.6 2.8e-06 27.4 8.6 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain WD40 PF00400.32 KFX98435.1 - 2.7e-07 31.2 0.1 0.00031 21.5 0.1 2.6 2 0 0 2 2 2 2 WD domain, G-beta repeat AHSP PF09236.10 KFX98435.1 - 0.23 11.9 0.2 0.39 11.2 0.2 1.3 1 0 0 1 1 1 0 Alpha-haemoglobin stabilising protein GatB_N PF02934.15 KFX98442.1 - 4.1e-98 328.1 0.0 5.3e-98 327.8 0.0 1.1 1 0 0 1 1 1 1 GatB/GatE catalytic domain Helo_like_N PF17111.5 KFX98445.1 - 2.5e-19 69.5 2.4 2.6e-19 69.5 1.4 1.5 1 1 0 1 1 1 1 Fungal N-terminal domain of STAND proteins Ribosomal_L9_C PF03948.14 KFX98445.1 - 0.072 13.6 0.2 0.17 12.4 0.2 1.6 1 0 0 1 1 1 0 Ribosomal protein L9, C-terminal domain DASH_Spc19 PF08287.11 KFX98445.1 - 0.36 10.7 7.8 0.65 9.9 5.6 2.0 2 0 0 2 2 2 0 Spc19 Snapin_Pallidin PF14712.6 KFX98445.1 - 1.6 9.2 5.9 2.3 8.7 0.6 3.0 3 0 0 3 3 3 0 Snapin/Pallidin HR1 PF02185.16 KFX98445.1 - 9.8 6.4 9.0 6.6 6.9 0.7 3.2 3 2 0 3 3 3 0 Hr1 repeat PXA PF02194.15 KFX98468.1 - 7.9e-16 58.5 0.0 1.1e-15 58.1 0.0 1.1 1 0 0 1 1 1 1 PXA domain FH2 PF02181.23 KFX98470.1 - 4e-83 279.6 7.4 5.3e-83 279.2 7.4 1.1 1 0 0 1 1 1 1 Formin Homology 2 Domain SET PF00856.28 KFX98479.1 - 6.1e-16 59.3 0.3 6.1e-16 59.3 0.3 3.3 3 1 0 3 3 3 1 SET domain AWS PF17907.1 KFX98479.1 - 1.2e-09 38.0 3.0 1.2e-09 38.0 3.0 2.5 2 0 0 2 2 2 1 AWS domain His_Phos_2 PF00328.22 KFX98485.1 - 1e-64 219.3 0.1 1.7e-64 218.6 0.1 1.3 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Gly_transf_sug PF04488.15 KFX98494.1 - 9e-11 42.3 0.1 1.9e-10 41.2 0.1 1.5 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif L_HMGIC_fpl PF10242.9 KFX98494.1 - 0.0031 17.8 0.0 0.0059 16.8 0.0 1.4 1 0 0 1 1 1 1 Lipoma HMGIC fusion partner-like protein AA_permease_2 PF13520.6 KFX98495.1 - 1.8e-50 172.0 56.4 2.2e-50 171.7 56.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KFX98495.1 - 6.1e-21 74.6 47.7 8e-21 74.2 47.7 1.0 1 0 0 1 1 1 1 Amino acid permease Ig_GlcNase PF18368.1 KFX98496.1 - 1.7e-38 131.0 8.3 8.2e-34 115.9 0.2 3.7 4 0 0 4 4 4 2 Exo-beta-D-glucosaminidase Ig-fold domain Glyco_hydro_2 PF00703.21 KFX98496.1 - 8.5e-11 42.5 2.1 2.2e-10 41.2 0.0 2.7 3 0 0 3 3 3 1 Glycosyl hydrolases family 2 Mannosidase_ig PF17786.1 KFX98496.1 - 1.7e-08 35.0 9.4 6.8e-08 33.0 0.6 3.9 3 1 1 4 4 4 1 Mannosidase Ig/CBM-like domain Ig_mannosidase PF17753.1 KFX98496.1 - 0.0002 21.1 4.3 0.00021 21.0 0.1 3.1 4 0 0 4 4 4 1 Ig-fold domain Glyco_hydro_2_N PF02837.18 KFX98496.1 - 0.00021 21.2 0.3 0.00075 19.4 0.0 2.0 2 0 0 2 2 2 1 Glycosyl hydrolases family 2, sugar binding domain Big_5 PF13205.6 KFX98496.1 - 0.0039 17.9 0.3 0.02 15.6 0.3 2.2 1 0 0 1 1 1 1 Bacterial Ig-like domain DUF4232 PF14016.6 KFX98496.1 - 0.014 15.5 3.7 0.017 15.3 0.2 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF4232) Glyco_hydro_2_C PF02836.17 KFX98496.1 - 0.044 12.9 0.0 0.08 12.0 0.0 1.4 1 0 0 1 1 1 0 Glycosyl hydrolases family 2, TIM barrel domain Zn_clus PF00172.18 KFX98497.1 - 4.5e-06 26.7 10.3 4.5e-06 26.7 10.3 1.6 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ADH_zinc_N PF00107.26 KFX98498.1 - 3.7e-10 39.9 0.0 6.5e-10 39.1 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KFX98498.1 - 6.1e-09 35.7 0.0 1.8e-08 34.2 0.0 1.8 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain Epimerase PF01370.21 KFX98498.1 - 0.0029 17.1 0.0 0.0039 16.7 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KFX98498.1 - 0.012 15.1 0.0 0.015 14.7 0.0 1.1 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase ADH_zinc_N_2 PF13602.6 KFX98498.1 - 0.02 15.9 0.0 0.041 14.9 0.0 1.7 1 1 0 1 1 1 0 Zinc-binding dehydrogenase ADH_N_2 PF16884.5 KFX98498.1 - 0.12 12.3 0.0 0.23 11.4 0.0 1.4 1 0 0 1 1 1 0 N-terminal domain of oxidoreductase Flavin_Reduct PF01613.18 KFX98499.1 - 1.4e-09 38.1 0.0 2.3e-09 37.5 0.0 1.3 1 0 0 1 1 1 1 Flavin reductase like domain DUF447 PF04289.12 KFX98499.1 - 0.00067 19.5 0.3 0.0027 17.5 0.3 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF447) Putative_PNPOx PF01243.20 KFX98499.1 - 0.041 14.1 0.1 0.071 13.3 0.1 1.3 1 0 0 1 1 1 0 Pyridoxamine 5'-phosphate oxidase Transferase PF02458.15 KFX98500.1 - 1.2e-34 119.8 0.0 5.9e-17 61.4 0.0 2.9 2 1 0 2 2 2 2 Transferase family Peptidase_S58 PF03576.14 KFX98501.1 - 4e-90 302.4 2.7 4.9e-90 302.1 2.7 1.0 1 0 0 1 1 1 1 Peptidase family S58 Glyco_hydro_7 PF00840.20 KFX98502.1 - 2.6e-148 494.4 1.9 3.3e-148 494.0 1.9 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 7 Notch PF00066.17 KFX98502.1 - 0.7 10.4 0.1 0.7 10.4 0.1 4.4 5 1 0 5 5 5 0 LNR domain ADH_zinc_N PF00107.26 KFX98503.1 - 2.9e-23 82.2 0.0 5.2e-23 81.4 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KFX98503.1 - 5.2e-14 53.4 0.0 1.1e-13 52.4 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KFX98503.1 - 4.5e-07 29.7 0.0 1.4e-06 28.2 0.0 1.9 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_N_2 PF16884.5 KFX98503.1 - 0.0083 16.0 0.0 0.015 15.2 0.0 1.3 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase U-box PF04564.15 KFX98505.1 - 2.1e-20 72.7 0.0 3.6e-20 71.9 0.0 1.4 1 0 0 1 1 1 1 U-box domain TPR_1 PF00515.28 KFX98505.1 - 8.3e-07 28.6 4.7 0.0043 16.8 0.2 3.6 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 KFX98505.1 - 1.7e-05 24.4 1.1 0.00013 21.5 0.0 2.4 2 0 0 2 2 2 1 TPR repeat TPR_2 PF07719.17 KFX98505.1 - 4.2e-05 23.3 6.0 0.0066 16.5 0.2 3.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.6 KFX98505.1 - 0.00026 21.6 4.5 0.00082 20.0 0.1 2.9 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.6 KFX98505.1 - 0.0028 17.7 3.0 2.2 8.7 0.0 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.6 KFX98505.1 - 0.0048 17.2 0.2 0.037 14.4 0.0 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_9 PF13371.6 KFX98505.1 - 0.018 15.2 2.3 0.022 14.9 0.0 2.3 3 0 0 3 3 3 0 Tetratricopeptide repeat zf-Nse PF11789.8 KFX98505.1 - 0.13 12.1 0.0 0.43 10.4 0.0 1.7 1 1 1 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit zf-NOSIP PF15906.5 KFX98505.1 - 0.15 12.2 0.0 0.41 10.8 0.0 1.7 1 0 0 1 1 1 0 Zinc-finger of nitric oxide synthase-interacting protein TPR_12 PF13424.6 KFX98505.1 - 0.36 11.2 8.1 4.2 7.7 0.8 3.3 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 KFX98505.1 - 0.63 11.0 7.3 1.3 10.1 0.5 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat Med8 PF10232.9 KFX98505.1 - 1.3 8.6 3.7 1.7 8.2 3.1 1.5 1 1 0 1 1 1 0 Mediator of RNA polymerase II transcription complex subunit 8 TPR_19 PF14559.6 KFX98505.1 - 1.5 9.4 6.8 3.3 8.3 0.6 2.4 1 1 1 2 2 2 0 Tetratricopeptide repeat UQ_con PF00179.26 KFX98507.1 - 1.1e-49 167.8 0.0 2.3e-49 166.6 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme NAD_binding_6 PF08030.12 KFX98507.1 - 4.2e-32 111.4 0.0 1.3e-31 109.8 0.0 1.9 2 0 0 2 2 2 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.19 KFX98507.1 - 2.1e-20 73.1 18.8 1.7e-19 70.2 13.0 2.4 1 1 1 2 2 2 2 Ferric reductase like transmembrane component FAD_binding_8 PF08022.12 KFX98507.1 - 6.2e-20 71.3 0.0 1.6e-19 70.0 0.0 1.8 1 0 0 1 1 1 1 FAD-binding domain 2-Hacid_dh PF00389.30 KFX98507.1 - 0.0086 15.7 0.0 0.018 14.7 0.0 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain Prok-E2_B PF14461.6 KFX98507.1 - 0.075 12.7 0.0 0.17 11.6 0.0 1.5 1 0 0 1 1 1 0 Prokaryotic E2 family B NAD_binding_1 PF00175.21 KFX98507.1 - 0.17 12.5 0.0 0.43 11.2 0.0 1.7 1 1 0 1 1 1 0 Oxidoreductase NAD-binding domain Acyl-CoA_dh_N PF02771.16 KFX98508.1 - 3.2e-24 85.8 0.6 5.9e-24 84.9 0.1 1.7 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_1 PF00441.24 KFX98508.1 - 1e-21 77.7 0.1 1.8e-21 76.9 0.1 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 KFX98508.1 - 7.4e-17 61.3 0.0 1.3e-16 60.6 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 KFX98508.1 - 3.8e-05 24.0 0.1 0.0001 22.5 0.1 1.8 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain XPG_I PF00867.18 KFX98509.1 - 5e-32 110.1 1.3 2.8e-31 107.7 0.0 2.3 2 0 0 2 2 2 1 XPG I-region XPG_N PF00752.17 KFX98509.1 - 1.2e-20 73.8 0.1 2.4e-19 69.7 0.0 2.8 2 1 0 2 2 2 1 XPG N-terminal domain 5_3_exonuc PF01367.20 KFX98509.1 - 1.3e-05 25.7 0.3 0.00016 22.2 0.0 2.5 2 0 0 2 2 2 1 5'-3' exonuclease, C-terminal SAM fold Linker_histone PF00538.19 KFX98510.1 - 2.2e-27 95.2 0.8 6.3e-27 93.8 0.8 1.7 1 0 0 1 1 1 1 linker histone H1 and H5 family RR_TM4-6 PF06459.12 KFX98510.1 - 5.4 6.8 13.2 8.2 6.2 13.2 1.4 1 1 0 1 1 1 0 Ryanodine Receptor TM 4-6 PIP5K PF01504.18 KFX98511.1 - 1.9e-100 335.6 1.2 2.3e-100 335.3 0.1 1.7 2 0 0 2 2 2 1 Phosphatidylinositol-4-phosphate 5-Kinase IBR PF01485.21 KFX98512.1 - 1.8e-21 76.1 46.6 1.8e-11 44.1 5.2 4.4 3 1 1 4 4 4 3 IBR domain, a half RING-finger domain zf-C3HC4 PF00097.25 KFX98512.1 - 0.00051 19.9 6.6 0.00051 19.9 6.6 4.6 3 1 1 4 4 4 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KFX98512.1 - 0.0075 16.1 4.7 0.0075 16.1 4.7 5.1 3 1 1 4 4 4 2 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KFX98512.1 - 0.0097 16.2 43.3 0.012 16.0 7.3 4.2 2 1 1 3 3 3 1 Ring finger domain zf-C3HC4_4 PF15227.6 KFX98512.1 - 0.016 15.4 26.2 0.13 12.5 0.8 4.6 3 1 0 3 3 3 0 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.6 KFX98512.1 - 0.56 10.3 34.6 0.053 13.6 5.1 3.9 3 1 0 3 3 3 0 RING-type zinc-finger zf-RING_4 PF14570.6 KFX98512.1 - 7.2 6.5 40.2 1.5 8.7 9.3 4.1 3 1 0 3 3 3 0 RING/Ubox like zinc-binding domain XPG_I PF00867.18 KFX98513.1 - 3.8e-24 84.9 0.1 9.8e-24 83.5 0.1 1.8 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.17 KFX98513.1 - 1.4e-20 73.6 0.0 3.1e-20 72.5 0.0 1.6 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I_2 PF12813.7 KFX98513.1 - 0.0014 18.2 0.1 0.003 17.1 0.0 1.6 2 0 0 2 2 2 1 XPG domain containing Tma16 PF11176.8 KFX98514.1 - 8.6e-47 158.7 0.2 1.1e-46 158.4 0.2 1.1 1 0 0 1 1 1 1 Translation machinery-associated protein 16 MAM33 PF02330.16 KFX98515.1 - 1.8e-74 250.3 5.0 2.1e-74 250.0 5.0 1.1 1 0 0 1 1 1 1 Mitochondrial glycoprotein Cnd1_N PF12922.7 KFX98516.1 - 5.3e-63 211.8 0.2 4.9e-62 208.7 0.2 2.5 2 0 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1, N-term Cnd1 PF12717.7 KFX98516.1 - 8.8e-48 162.4 3.1 2.8e-43 147.8 1.0 3.3 3 0 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 KFX98516.1 - 1.5e-09 37.3 5.6 0.031 14.5 0.0 6.2 6 0 0 6 6 6 3 HEAT repeat HEAT_2 PF13646.6 KFX98516.1 - 5e-09 36.4 4.2 0.00044 20.6 0.0 4.8 5 1 0 6 6 5 2 HEAT repeats HEAT_EZ PF13513.6 KFX98516.1 - 2e-05 25.0 9.7 0.13 12.8 0.1 5.9 7 0 0 7 7 5 1 HEAT-like repeat RTP1_C1 PF10363.9 KFX98516.1 - 0.00023 21.3 0.2 0.71 10.1 0.0 3.6 3 0 0 3 3 3 2 Required for nuclear transport of RNA pol II C-terminus 1 Cnd3 PF12719.7 KFX98516.1 - 0.0046 16.2 1.4 0.0046 16.2 1.4 2.8 4 0 0 4 4 4 1 Nuclear condensing complex subunits, C-term domain p450 PF00067.22 KFX98516.1 - 0.063 12.0 0.6 0.12 11.1 0.6 1.4 1 0 0 1 1 1 0 Cytochrome P450 IFN-gamma PF00714.17 KFX98516.1 - 0.11 12.3 0.0 0.34 10.8 0.0 1.9 1 0 0 1 1 1 0 Interferon gamma DUF573 PF04504.14 KFX98516.1 - 0.19 12.4 1.1 4.2 8.1 0.2 3.1 2 0 0 2 2 2 0 Protein of unknown function, DUF573 VHS PF00790.19 KFX98516.1 - 0.27 11.1 1.8 2.6 7.9 0.0 3.3 3 0 0 3 3 3 0 VHS domain Pkinase PF00069.25 KFX98517.1 - 8.5e-42 143.3 0.0 1.1e-38 133.1 0.0 3.0 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KFX98517.1 - 1.1e-12 47.8 0.0 8.5e-07 28.5 0.0 3.6 3 1 0 3 3 3 2 Protein tyrosine kinase Kinase-like PF14531.6 KFX98517.1 - 0.00027 20.4 0.0 0.65 9.3 0.0 2.2 2 0 0 2 2 2 2 Kinase-like Pkinase_fungal PF17667.1 KFX98517.1 - 0.0015 17.4 0.0 0.0026 16.6 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KFX98517.1 - 0.0099 15.8 0.0 0.072 13.0 0.0 2.2 1 1 1 2 2 2 1 Phosphotransferase enzyme family Ribosomal_L27A PF00828.19 KFX98518.1 - 1.5e-21 77.4 0.0 2.6e-21 76.6 0.0 1.4 1 1 1 2 2 2 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A Helicase_C_2 PF13307.6 KFX98519.1 - 3.2e-55 186.9 0.0 8.2e-55 185.6 0.0 1.7 1 0 0 1 1 1 1 Helicase C-terminal domain DEAD_2 PF06733.15 KFX98519.1 - 1.9e-51 174.2 0.0 3.3e-51 173.4 0.0 1.4 1 0 0 1 1 1 1 DEAD_2 PNP_UDP_1 PF01048.20 KFX98532.1 - 4.6e-05 22.8 0.0 5.1e-05 22.6 0.0 1.1 1 0 0 1 1 1 1 Phosphorylase superfamily DIT1_PvcA PF05141.12 KFX98532.1 - 0.014 14.8 0.1 2.9 7.3 0.0 2.2 2 0 0 2 2 2 0 Pyoverdine/dityrosine biosynthesis protein HsbA PF12296.8 KFX98533.1 - 8.1e-18 65.0 3.1 1.2e-17 64.5 3.1 1.3 1 0 0 1 1 1 1 Hydrophobic surface binding protein A Sugar_tr PF00083.24 KFX98534.1 - 2.3e-94 316.8 16.6 2.7e-94 316.6 16.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KFX98534.1 - 1.7e-31 109.4 34.0 5.3e-27 94.7 25.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 KFX98534.1 - 0.0024 16.5 14.5 0.0091 14.6 3.3 2.4 2 0 0 2 2 2 2 MFS/sugar transport protein Claudin_2 PF13903.6 KFX98534.1 - 0.055 13.2 5.0 0.1 12.3 0.1 3.0 3 0 0 3 3 3 0 PMP-22/EMP/MP20/Claudin tight junction AnmK PF03702.14 KFX98535.1 - 2.1e-89 300.2 0.0 2.4e-89 300.0 0.0 1.0 1 0 0 1 1 1 1 Anhydro-N-acetylmuramic acid kinase Methyltransf_2 PF00891.18 KFX98535.1 - 0.0011 18.3 0.0 0.002 17.5 0.0 1.4 1 0 0 1 1 1 1 O-methyltransferase domain Peptidase_M22 PF00814.25 KFX98535.1 - 0.016 14.9 0.0 0.15 11.7 0.0 2.0 2 0 0 2 2 2 0 Glycoprotease family Fibrillarin_2 PF10113.9 KFX98535.1 - 0.14 10.7 0.0 0.2 10.2 0.0 1.1 1 0 0 1 1 1 0 Fibrillarin-like archaeal protein Fungal_trans PF04082.18 KFX98536.1 - 4.6e-14 52.1 0.2 1e-13 51.0 0.2 1.5 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KFX98536.1 - 0.00051 20.1 10.8 0.00092 19.3 10.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KFX98537.1 - 1.6e-28 99.5 0.1 2.3e-28 99.0 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KFX98537.1 - 3.6e-08 33.4 11.8 5.8e-08 32.7 11.8 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Gal4_dimer PF03902.13 KFX98537.1 - 0.00013 22.1 0.0 0.00027 21.0 0.0 1.5 1 0 0 1 1 1 1 Gal4-like dimerisation domain Sugar_tr PF00083.24 KFX98538.1 - 1.8e-117 393.0 16.6 2.9e-117 392.3 16.6 1.3 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KFX98538.1 - 4.1e-21 75.3 44.9 1.5e-10 40.5 20.2 2.3 1 1 0 2 2 2 2 Major Facilitator Superfamily PRK PF00485.18 KFX98539.1 - 3.3e-06 27.0 0.0 4e-06 26.7 0.0 1.1 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family AAA_18 PF13238.6 KFX98539.1 - 0.00034 21.2 0.0 0.0015 19.1 0.0 2.2 1 1 1 2 2 2 1 AAA domain AAA_33 PF13671.6 KFX98539.1 - 0.00085 19.5 0.3 0.12 12.6 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 KFX98539.1 - 0.0018 18.0 0.0 0.0037 17.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 KFX98539.1 - 0.0025 17.1 0.0 0.0057 15.9 0.0 1.6 1 0 0 1 1 1 1 Zeta toxin AAA_28 PF13521.6 KFX98539.1 - 0.0029 17.9 0.0 0.0058 16.9 0.0 1.7 2 0 0 2 2 1 1 AAA domain AAA_16 PF13191.6 KFX98539.1 - 0.0033 17.8 0.0 0.0043 17.5 0.0 1.4 1 1 0 1 1 1 1 AAA ATPase domain NB-ARC PF00931.22 KFX98539.1 - 0.0064 15.7 0.0 0.019 14.1 0.0 1.7 2 0 0 2 2 2 1 NB-ARC domain MeaB PF03308.16 KFX98539.1 - 0.016 14.2 0.0 0.025 13.6 0.0 1.2 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Ploopntkinase3 PF18751.1 KFX98539.1 - 0.034 14.1 0.0 0.063 13.2 0.0 1.4 1 0 0 1 1 1 0 P-loop Nucleotide Kinase3 KTI12 PF08433.10 KFX98539.1 - 0.042 13.3 0.0 0.067 12.6 0.0 1.3 1 0 0 1 1 1 0 Chromatin associated protein KTI12 NACHT PF05729.12 KFX98539.1 - 0.042 13.8 0.0 0.1 12.5 0.0 1.7 1 0 0 1 1 1 0 NACHT domain CoaE PF01121.20 KFX98539.1 - 0.05 13.3 0.5 6.9 6.3 0.0 2.1 2 0 0 2 2 2 0 Dephospho-CoA kinase Mg_chelatase PF01078.21 KFX98539.1 - 0.056 12.8 0.0 0.42 10.0 0.0 2.1 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI T2SSE PF00437.20 KFX98539.1 - 0.069 12.2 0.1 0.12 11.4 0.1 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein MMR_HSR1 PF01926.23 KFX98539.1 - 0.097 12.8 0.0 0.24 11.5 0.0 1.7 2 0 0 2 2 2 0 50S ribosome-binding GTPase SRP54 PF00448.22 KFX98539.1 - 0.1 12.2 0.0 0.18 11.4 0.0 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain ABC_tran PF00005.27 KFX98539.1 - 0.13 12.8 0.0 0.24 11.9 0.0 1.5 1 0 0 1 1 1 0 ABC transporter AAA PF00004.29 KFX98539.1 - 0.15 12.5 0.0 0.25 11.8 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Stc1 PF12898.7 KFX98544.1 - 6.1e-18 65.2 12.5 1.1e-17 64.3 12.5 1.5 1 0 0 1 1 1 1 Stc1 domain His_Me_b4a2 PF18275.1 KFX98544.1 - 0.51 10.4 7.9 0.65 10.1 3.1 2.5 2 0 0 2 2 2 0 His-Me finger endonuclease beta4-alpha2 domain zf-CHY PF05495.12 KFX98544.1 - 1.6 9.2 10.6 0.38 11.3 5.6 2.1 1 1 1 2 2 2 0 CHY zinc finger zf-CCHC_2 PF13696.6 KFX98544.1 - 3.4 7.6 5.9 0.23 11.3 0.4 1.9 2 0 0 2 2 2 0 Zinc knuckle Cyclin_N PF00134.23 KFX98551.1 - 1.5e-10 40.9 1.0 2.3e-10 40.3 0.2 1.7 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C_2 PF16899.5 KFX98551.1 - 0.035 14.5 0.5 0.1 13.0 0.2 1.9 2 0 0 2 2 2 0 Cyclin C-terminal domain Mito_carr PF00153.27 KFX98552.1 - 1.1e-66 220.7 6.0 5e-22 77.6 0.2 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein EF-hand_1 PF00036.32 KFX98552.1 - 2.3e-19 67.4 6.4 6.6e-06 25.3 0.1 4.4 4 0 0 4 4 4 3 EF hand EF-hand_7 PF13499.6 KFX98552.1 - 1.5e-18 67.0 2.2 2.6e-08 34.2 0.2 2.3 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 KFX98552.1 - 2.5e-16 58.1 8.1 0.00089 19.0 0.1 4.5 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 KFX98552.1 - 2.7e-15 55.1 8.7 2.4e-06 26.8 0.1 3.5 3 0 0 3 3 3 3 EF hand EF-hand_8 PF13833.6 KFX98552.1 - 7.1e-13 48.2 3.9 2.2e-06 27.4 0.1 3.4 1 1 2 3 3 3 3 EF-hand domain pair SPARC_Ca_bdg PF10591.9 KFX98552.1 - 1.2e-05 25.6 0.0 0.13 12.6 0.0 2.3 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_9 PF14658.6 KFX98552.1 - 0.0013 19.0 0.7 0.85 10.0 0.0 3.6 3 1 1 4 4 4 2 EF-hand domain SET PF00856.28 KFX98598.1 - 5.1e-11 43.2 0.0 9e-11 42.4 0.0 1.6 1 1 0 1 1 1 1 SET domain zf-MYND PF01753.18 KFX98598.1 - 4.4e-06 26.7 8.4 4.4e-06 26.7 8.4 2.0 2 0 0 2 2 2 1 MYND finger AhpC-TSA PF00578.21 KFX98599.1 - 2.6e-30 104.9 0.0 3.7e-30 104.4 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 KFX98599.1 - 5.7e-13 48.8 0.0 7.6e-13 48.4 0.0 1.1 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.9 KFX98599.1 - 4.3e-11 42.5 0.1 8.1e-11 41.6 0.1 1.5 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin DNA_ligase_A_M PF01068.21 KFX98601.1 - 1.7e-45 155.2 0.0 3.2e-45 154.3 0.0 1.5 1 0 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.14 KFX98601.1 - 3.7e-42 144.6 0.0 7.2e-42 143.6 0.0 1.5 1 0 0 1 1 1 1 DNA ligase N terminus RNA_ligase PF09414.10 KFX98601.1 - 8.5e-17 61.9 0.0 1.9e-16 60.8 0.0 1.6 1 0 0 1 1 1 1 RNA ligase DNA_ligase_A_C PF04679.15 KFX98601.1 - 1.3e-14 54.6 0.0 3.8e-14 53.1 0.0 1.9 1 0 0 1 1 1 1 ATP dependent DNA ligase C terminal region BRCT_2 PF16589.5 KFX98601.1 - 3.8e-14 52.9 0.0 2.6e-08 34.1 0.0 2.8 3 0 0 3 3 3 2 BRCT domain, a BRCA1 C-terminus domain LIG3_BRCT PF16759.5 KFX98601.1 - 1.4e-07 31.7 0.6 0.00025 21.3 0.0 2.5 2 0 0 2 2 2 2 DNA ligase 3 BRCT domain BRCT PF00533.26 KFX98601.1 - 3.2e-06 27.4 0.1 1.3e-05 25.5 0.0 2.1 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain DNA_ligase_IV PF11411.8 KFX98601.1 - 0.0001 22.3 0.0 0.00025 21.1 0.0 1.7 1 0 0 1 1 1 1 DNA ligase IV UPRTase PF14681.6 KFX98602.1 - 2.4e-71 239.5 0.0 2.8e-71 239.2 0.0 1.0 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.27 KFX98602.1 - 5.6e-05 22.7 0.1 0.00012 21.6 0.1 1.6 1 1 0 1 1 1 1 Phosphoribosyl transferase domain Pribosyl_synth PF14572.6 KFX98602.1 - 0.0004 20.5 0.0 0.00061 19.9 0.0 1.2 1 0 0 1 1 1 1 Phosphoribosyl synthetase-associated domain TMP-TENI PF02581.17 KFX98602.1 - 0.051 12.9 0.4 0.87 8.9 0.1 2.1 2 0 0 2 2 2 0 Thiamine monophosphate synthase P5CR_dimer PF14748.6 KFX98602.1 - 0.083 13.2 0.0 0.16 12.2 0.0 1.4 1 0 0 1 1 1 0 Pyrroline-5-carboxylate reductase dimerisation Zn_clus PF00172.18 KFX98604.1 - 1.1e-06 28.7 11.9 1.6e-06 28.1 11.9 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Sad1_UNC PF07738.13 KFX98605.1 - 5.7e-09 36.1 0.0 3.7e-07 30.2 0.0 2.5 1 1 0 1 1 1 1 Sad1 / UNC-like C-terminal T3SS_basalb_I PF17001.5 KFX98605.1 - 0.21 12.2 2.1 6.3 7.5 1.5 2.6 2 0 0 2 2 2 0 Type III secretion basal body protein I, YscI, HrpB, PscI GDP_Man_Dehyd PF16363.5 KFX98606.1 - 1.6e-51 175.6 0.0 2.2e-51 175.2 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 KFX98606.1 - 7.1e-48 163.2 0.0 9.3e-48 162.8 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KFX98606.1 - 1.8e-16 60.0 0.0 3e-16 59.3 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 KFX98606.1 - 2.7e-14 53.0 0.0 1.8e-12 47.0 0.0 2.1 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 KFX98606.1 - 4.5e-12 45.7 0.0 6.4e-12 45.2 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain adh_short PF00106.25 KFX98606.1 - 1.7e-09 37.4 0.0 2.8e-09 36.7 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KFX98606.1 - 2.6e-09 37.3 0.0 4.1e-09 36.6 0.0 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_4 PF07993.12 KFX98606.1 - 1.7e-06 27.4 0.0 0.00013 21.2 0.0 2.2 1 1 0 1 1 1 1 Male sterility protein adh_short_C2 PF13561.6 KFX98606.1 - 0.00032 20.3 0.0 0.00063 19.4 0.0 1.4 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase UDPG_MGDP_dh_N PF03721.14 KFX98606.1 - 0.012 15.2 0.0 0.019 14.5 0.0 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NmrA PF05368.13 KFX98606.1 - 0.054 13.0 0.0 0.3 10.6 0.0 2.0 2 0 0 2 2 2 0 NmrA-like family Biotin_lipoyl PF00364.22 KFX98613.1 - 7.4e-20 70.6 1.4 1.4e-19 69.7 0.8 1.8 2 0 0 2 2 2 1 Biotin-requiring enzyme E3_binding PF02817.17 KFX98613.1 - 8.2e-06 26.1 1.3 2.4e-05 24.6 0.0 2.6 2 0 0 2 2 2 1 e3 binding domain Biotin_lipoyl_2 PF13533.6 KFX98613.1 - 0.00054 19.7 0.7 0.0032 17.2 0.0 2.5 2 0 0 2 2 2 1 Biotin-lipoyl like HTH_Tnp_ISL3 PF13542.6 KFX98613.1 - 0.11 11.9 1.4 0.18 11.3 0.8 1.7 2 0 0 2 2 2 0 Helix-turn-helix domain of transposase family ISL3 DUF3306 PF11748.8 KFX98613.1 - 1.3 9.9 11.4 1.4 9.8 4.5 3.0 2 1 0 2 2 2 0 Protein of unknown function (DUF3306) Methyltransf_11 PF08241.12 KFX98614.1 - 8.3e-11 42.4 0.0 1.9e-10 41.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KFX98614.1 - 8.3e-11 42.5 0.0 2.4e-10 41.0 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 KFX98614.1 - 3.6e-09 37.2 0.0 8.3e-09 36.1 0.0 1.5 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 KFX98614.1 - 3.7e-06 26.5 0.0 7.2e-06 25.5 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.6 KFX98614.1 - 0.00015 21.7 0.0 0.00022 21.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KFX98614.1 - 0.00021 21.1 0.0 0.00044 20.1 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain DREV PF05219.12 KFX98614.1 - 0.2 10.7 0.0 0.31 10.1 0.0 1.3 1 0 0 1 1 1 0 DREV methyltransferase AAA_2 PF07724.14 KFX98615.1 - 2.2e-47 161.3 0.0 3.3e-46 157.5 0.0 2.7 3 0 0 3 3 2 1 AAA domain (Cdc48 subfamily) AAA_lid_9 PF17871.1 KFX98615.1 - 1.8e-32 111.4 2.7 1.8e-32 111.4 2.7 3.7 3 1 0 4 4 3 1 AAA lid domain AAA PF00004.29 KFX98615.1 - 7.2e-26 91.2 0.1 6.3e-14 52.5 0.0 3.2 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.9 KFX98615.1 - 2.5e-25 88.3 0.3 9e-25 86.5 0.3 2.1 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA_5 PF07728.14 KFX98615.1 - 1.6e-14 54.0 0.0 5.8e-09 36.1 0.0 3.2 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 KFX98615.1 - 3.9e-12 46.6 0.0 0.00016 21.9 0.0 4.3 2 1 1 3 3 2 2 AAA domain AAA_16 PF13191.6 KFX98615.1 - 2.1e-11 44.5 10.3 5.1e-06 27.0 0.1 5.6 5 1 0 5 5 4 2 AAA ATPase domain Sigma54_activat PF00158.26 KFX98615.1 - 6.4e-08 32.5 0.0 3.9e-05 23.4 0.0 2.6 2 1 0 2 2 2 1 Sigma-54 interaction domain Mg_chelatase PF01078.21 KFX98615.1 - 3.8e-06 26.4 0.0 0.24 10.8 0.0 3.5 3 0 0 3 3 3 2 Magnesium chelatase, subunit ChlI AAA_18 PF13238.6 KFX98615.1 - 5.9e-06 26.9 0.1 0.062 13.9 0.0 3.5 3 0 0 3 3 2 2 AAA domain AAA_7 PF12775.7 KFX98615.1 - 6.1e-06 25.9 0.0 0.022 14.3 0.0 2.8 3 0 0 3 3 2 2 P-loop containing dynein motor region IstB_IS21 PF01695.17 KFX98615.1 - 7.1e-06 25.9 0.0 0.082 12.6 0.0 2.7 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_33 PF13671.6 KFX98615.1 - 7.5e-06 26.2 0.0 0.27 11.4 0.0 3.4 2 1 0 2 2 2 2 AAA domain AAA_14 PF13173.6 KFX98615.1 - 1.7e-05 24.9 0.0 0.22 11.6 0.0 3.0 3 0 0 3 3 2 2 AAA domain TniB PF05621.11 KFX98615.1 - 1.9e-05 24.2 0.4 0.24 10.8 0.0 4.6 4 1 0 4 4 4 1 Bacterial TniB protein RNA_helicase PF00910.22 KFX98615.1 - 7.5e-05 23.1 0.0 0.53 10.7 0.0 2.7 2 0 0 2 2 2 2 RNA helicase Clp_N PF02861.20 KFX98615.1 - 7.5e-05 22.8 3.3 0.0054 16.8 0.1 3.8 3 0 0 3 3 3 1 Clp amino terminal domain, pathogenicity island component AAA_28 PF13521.6 KFX98615.1 - 8.7e-05 22.8 0.1 0.52 10.6 0.0 3.2 3 0 0 3 3 2 2 AAA domain AAA_24 PF13479.6 KFX98615.1 - 0.00014 21.6 0.0 0.18 11.5 0.0 2.9 2 0 0 2 2 2 2 AAA domain AAA_3 PF07726.11 KFX98615.1 - 0.00025 20.9 0.0 1.1 9.1 0.0 3.5 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) RsgA_GTPase PF03193.16 KFX98615.1 - 0.00039 20.4 0.2 0.49 10.3 0.0 3.1 3 0 0 3 3 2 1 RsgA GTPase RuvB_N PF05496.12 KFX98615.1 - 0.00051 19.8 0.2 8.5 6.1 0.0 4.6 5 0 0 5 5 4 0 Holliday junction DNA helicase RuvB P-loop domain AAA_30 PF13604.6 KFX98615.1 - 0.0006 19.6 0.0 1.8 8.3 0.0 3.3 4 0 0 4 4 2 2 AAA domain TsaE PF02367.17 KFX98615.1 - 0.00068 19.6 0.0 0.5 10.4 0.0 2.6 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_19 PF13245.6 KFX98615.1 - 0.00091 19.6 0.2 0.31 11.4 0.0 3.7 5 0 0 5 5 3 1 AAA domain ATPase_2 PF01637.18 KFX98615.1 - 0.0012 18.8 8.6 0.051 13.5 0.1 4.8 5 1 0 5 5 3 1 ATPase domain predominantly from Archaea T2SSE PF00437.20 KFX98615.1 - 0.0013 17.8 0.9 0.04 13.0 0.1 3.0 2 1 0 2 2 2 1 Type II/IV secretion system protein ABC_tran PF00005.27 KFX98615.1 - 0.0037 17.8 3.5 1 9.9 0.0 3.8 4 0 0 4 4 4 1 ABC transporter AAA_29 PF13555.6 KFX98615.1 - 0.0046 16.7 0.0 4 7.3 0.0 2.7 2 0 0 2 2 2 1 P-loop containing region of AAA domain NACHT PF05729.12 KFX98615.1 - 0.0078 16.2 0.0 0.72 9.8 0.0 2.6 2 0 0 2 2 2 1 NACHT domain Roc PF08477.13 KFX98615.1 - 0.01 16.1 0.0 3.4 7.9 0.0 2.7 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Zeta_toxin PF06414.12 KFX98615.1 - 0.01 15.1 0.0 0.97 8.7 0.0 2.7 2 0 0 2 2 2 0 Zeta toxin ResIII PF04851.15 KFX98615.1 - 0.011 15.8 0.0 2.4 8.1 0.0 3.6 3 0 0 3 3 3 0 Type III restriction enzyme, res subunit Torsin PF06309.11 KFX98615.1 - 0.012 15.7 0.0 0.1 12.7 0.0 2.4 3 0 0 3 3 2 0 Torsin Rad17 PF03215.15 KFX98615.1 - 0.026 14.4 0.0 9.1 6.2 0.0 2.5 2 0 0 2 2 2 0 Rad17 P-loop domain AAA_25 PF13481.6 KFX98615.1 - 0.03 13.9 1.4 3.2 7.3 0.0 3.1 3 0 0 3 3 3 0 AAA domain NTPase_1 PF03266.15 KFX98615.1 - 0.038 13.9 0.0 0.48 10.3 0.0 2.5 2 0 0 2 2 2 0 NTPase SRP54 PF00448.22 KFX98615.1 - 0.051 13.2 0.0 7.7 6.1 0.0 2.6 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_23 PF13476.6 KFX98615.1 - 0.081 13.4 0.0 0.081 13.4 0.0 4.8 4 2 1 5 5 3 0 AAA domain PduV-EutP PF10662.9 KFX98615.1 - 0.1 12.4 0.0 6.6 6.5 0.0 2.6 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_21 PF13304.6 KFX98615.1 - 0.11 12.3 0.5 7.2 6.3 0.0 3.5 4 0 0 4 4 4 0 AAA domain, putative AbiEii toxin, Type IV TA system V_ATPase_I PF01496.19 KFX98615.1 - 1.8 6.4 4.4 0.46 8.3 0.9 1.7 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family GAS PF13851.6 KFX98615.1 - 8.4 5.7 15.6 0.2 11.0 8.1 2.1 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding Mhr1 PF12829.7 KFX98616.1 - 7.9e-34 115.6 0.1 1.4e-33 114.8 0.1 1.4 1 0 0 1 1 1 1 Transcriptional regulation of mitochondrial recombination DUF3431 PF11913.8 KFX98617.1 - 2.2e-89 298.9 1.6 2.8e-89 298.5 1.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3431) Phasin PF05597.11 KFX98617.1 - 0.06 13.3 0.2 0.094 12.7 0.2 1.3 1 0 0 1 1 1 0 Poly(hydroxyalcanoate) granule associated protein (phasin) Phage_TAC_5 PF08890.11 KFX98617.1 - 0.12 12.3 1.6 1.5 8.9 0.2 2.4 1 1 1 2 2 2 0 Phage XkdN-like tail assembly chaperone protein, TAC HlyD_D23 PF16576.5 KFX98617.1 - 0.16 11.1 0.0 0.27 10.4 0.0 1.3 1 0 0 1 1 1 0 Barrel-sandwich domain of CusB or HlyD membrane-fusion Myb_DNA-bind_7 PF15963.5 KFX98618.1 - 6.2e-24 83.7 1.0 6.2e-24 83.7 1.0 2.4 3 0 0 3 3 3 1 Myb DNA-binding like NACHT PF05729.12 KFX98618.1 - 2.1e-08 34.3 0.1 1.7e-07 31.3 0.0 2.2 2 0 0 2 2 2 1 NACHT domain AAA_22 PF13401.6 KFX98618.1 - 9.6e-05 22.7 0.0 0.00035 20.8 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 KFX98618.1 - 0.00021 21.7 3.1 0.00058 20.3 0.0 2.6 2 1 0 2 2 2 1 AAA ATPase domain Myb_DNA-binding PF00249.31 KFX98618.1 - 0.00045 20.4 0.0 0.0015 18.7 0.0 1.9 1 0 0 1 1 1 1 Myb-like DNA-binding domain AAA PF00004.29 KFX98618.1 - 0.077 13.4 0.0 0.36 11.2 0.0 2.2 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) BRE1 PF08647.11 KFX98619.1 - 2.2e-27 95.0 5.0 2.2e-27 95.0 5.0 6.7 4 1 2 6 6 4 1 BRE1 E3 ubiquitin ligase zf-C3HC4_3 PF13920.6 KFX98619.1 - 2.5e-08 33.7 8.5 4e-08 33.0 8.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KFX98619.1 - 2.5e-07 30.4 11.7 4.4e-07 29.7 11.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KFX98619.1 - 8.9e-07 28.7 7.6 1.5e-06 27.9 7.6 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.6 KFX98619.1 - 1.6e-06 27.9 10.0 2.7e-06 27.1 10.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KFX98619.1 - 1.7e-06 27.9 6.2 3.1e-06 27.1 6.2 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_2 PF13639.6 KFX98619.1 - 2.3e-06 27.8 9.1 3.8e-06 27.1 9.1 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 KFX98619.1 - 6.3e-06 26.1 11.3 1e-05 25.4 11.3 1.4 1 0 0 1 1 1 1 zinc-RING finger domain ATG16 PF08614.11 KFX98619.1 - 0.0075 16.5 21.3 0.0075 16.5 21.3 6.0 3 2 3 6 6 6 2 Autophagy protein 16 (ATG16) DUF1272 PF06906.11 KFX98619.1 - 0.012 15.7 7.3 0.023 14.8 7.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) zf-RING_4 PF14570.6 KFX98619.1 - 0.076 12.8 7.4 0.24 11.2 7.4 1.8 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain zf-C3HC4_4 PF15227.6 KFX98619.1 - 0.097 12.8 6.5 0.18 12.0 6.5 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.7 KFX98619.1 - 0.21 11.9 9.3 1.1 9.6 9.3 2.1 1 1 0 1 1 1 0 RING-H2 zinc finger domain zf-UDP PF14569.6 KFX98619.1 - 0.25 11.5 3.9 0.73 10.0 3.9 1.7 1 0 0 1 1 1 0 Zinc-binding RING-finger zinc-ribbons_6 PF07191.12 KFX98619.1 - 1.5 8.8 7.7 0.77 9.8 2.9 2.3 1 1 1 2 2 2 0 zinc-ribbons FYVE PF01363.21 KFX98619.1 - 1.7 8.8 11.3 19 5.5 11.4 2.4 1 1 1 2 2 2 0 FYVE zinc finger zf-C2H2_jaz PF12171.8 KFX98619.1 - 1.8 9.0 7.2 47 4.4 0.1 3.9 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-ANAPC11 PF12861.7 KFX98619.1 - 2 8.5 4.8 7.6 6.7 4.8 1.9 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger DinB_2 PF12867.7 KFX98619.1 - 3.5 8.2 8.6 0.57 10.7 2.3 3.0 3 1 0 3 3 2 0 DinB superfamily zf-C2H2_4 PF13894.6 KFX98619.1 - 3.5 8.7 6.5 17 6.6 0.1 3.3 2 1 0 2 2 2 0 C2H2-type zinc finger Baculo_PEP_C PF04513.12 KFX98619.1 - 3.6 7.6 31.9 3.1 7.8 0.2 5.6 3 1 4 7 7 7 0 Baculovirus polyhedron envelope protein, PEP, C terminus SNF2_N PF00176.23 KFX98621.1 - 5e-63 212.9 0.3 5e-63 212.9 0.3 3.5 3 1 0 3 3 3 1 SNF2 family N-terminal domain HSA PF07529.13 KFX98621.1 - 3.6e-19 68.9 12.9 3.6e-19 68.9 12.9 3.6 3 1 2 5 5 5 1 HSA QLQ PF08880.11 KFX98621.1 - 5.2e-13 48.5 2.2 1e-12 47.6 0.9 2.3 2 0 0 2 2 2 1 QLQ ResIII PF04851.15 KFX98621.1 - 1.1e-11 45.0 0.0 1.1e-11 45.0 0.0 3.2 4 1 0 4 4 4 1 Type III restriction enzyme, res subunit Ubiq_cyt_C_chap PF03981.12 KFX98622.1 - 0.094 12.8 0.0 0.14 12.2 0.0 1.2 1 0 0 1 1 1 0 Ubiquinol-cytochrome C chaperone DUF805 PF05656.14 KFX98622.1 - 0.1 13.0 0.3 0.17 12.3 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF805) 5TM-5TMR_LYT PF07694.12 KFX98622.1 - 0.13 11.7 2.3 0.21 11.1 2.3 1.3 1 1 0 1 1 1 0 5TMR of 5TMR-LYT DUF4677 PF15726.5 KFX98625.1 - 0.032 14.4 0.6 0.032 14.4 0.6 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4677) Plasmodium_Vir PF05795.11 KFX98644.1 - 0.072 12.5 5.4 0.081 12.3 5.4 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein MYCBPAP PF14646.6 KFX98644.1 - 0.43 9.5 2.0 0.46 9.4 2.0 1.0 1 0 0 1 1 1 0 MYCBP-associated protein family Macoilin PF09726.9 KFX98644.1 - 1.4 7.4 10.2 1.5 7.3 10.2 1.0 1 0 0 1 1 1 0 Macoilin family Tim54 PF11711.8 KFX98644.1 - 1.8 7.2 4.6 2 7.1 4.6 1.0 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Apt1 PF10351.9 KFX98644.1 - 2.8 6.7 11.1 2.8 6.7 11.1 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain H_PPase PF03030.16 KFX98646.1 - 1.9 7.0 5.4 4.8 5.7 1.0 2.1 2 0 0 2 2 2 0 Inorganic H+ pyrophosphatase FAA_hydrolase PF01557.18 KFX98657.1 - 2.1e-67 227.0 0.0 2.6e-67 226.7 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family Glyoxalase PF00903.25 KFX98658.1 - 2.1e-06 27.9 3.7 4.6e-06 26.8 2.9 2.0 2 1 0 2 2 2 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 KFX98658.1 - 0.088 13.1 0.2 0.19 12.0 0.2 1.6 1 0 0 1 1 1 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Fungal_trans PF04082.18 KFX98659.1 - 3.9e-15 55.6 2.4 7.4e-15 54.7 2.4 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KFX98659.1 - 6.7e-08 32.5 7.6 1.6e-07 31.3 7.6 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain FAD_binding_3 PF01494.19 KFX98660.1 - 1.4e-48 166.0 0.0 1.6e-48 165.8 0.0 1.0 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 KFX98660.1 - 1.4e-06 28.2 0.1 0.00039 20.1 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 KFX98660.1 - 1.9e-05 23.9 0.0 0.0014 17.8 0.0 2.8 3 0 0 3 3 3 1 Lycopene cyclase protein Pyr_redox_2 PF07992.14 KFX98660.1 - 8.6e-05 21.9 0.0 0.00015 21.1 0.0 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KFX98660.1 - 0.00018 21.7 0.0 0.00041 20.5 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 KFX98660.1 - 0.00076 18.7 0.0 0.0011 18.2 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 KFX98660.1 - 0.00099 17.9 0.0 0.0018 17.1 0.0 1.4 1 0 0 1 1 1 1 HI0933-like protein GIDA PF01134.22 KFX98660.1 - 0.0069 15.5 0.0 0.011 14.8 0.0 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A Pyr_redox_3 PF13738.6 KFX98660.1 - 0.012 14.9 0.0 0.13 11.5 0.0 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KFX98660.1 - 0.03 14.3 0.1 0.068 13.2 0.1 1.6 1 0 0 1 1 1 0 FAD-NAD(P)-binding Thi4 PF01946.17 KFX98660.1 - 0.047 12.9 0.0 0.082 12.1 0.0 1.3 1 0 0 1 1 1 0 Thi4 family ApbE PF02424.15 KFX98660.1 - 0.069 12.7 0.0 0.12 11.8 0.0 1.3 1 0 0 1 1 1 0 ApbE family Pyr_redox PF00070.27 KFX98660.1 - 0.097 13.2 0.0 0.69 10.5 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.18 KFX98660.1 - 0.097 12.9 0.0 0.2 12.0 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain ApbA PF02558.16 KFX98660.1 - 0.098 12.3 0.0 0.17 11.5 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA FAD_oxidored PF12831.7 KFX98660.1 - 0.18 11.1 0.0 0.24 10.7 0.0 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase SnoaL_4 PF13577.6 KFX98661.1 - 1e-08 35.4 3.4 1.3e-08 35.0 3.4 1.2 1 0 0 1 1 1 1 SnoaL-like domain SnoaL_2 PF12680.7 KFX98661.1 - 0.0067 17.0 1.1 0.01 16.5 1.1 1.3 1 0 0 1 1 1 1 SnoaL-like domain Ring_hydroxyl_B PF00866.18 KFX98661.1 - 0.047 13.7 0.5 0.32 11.1 0.2 2.0 1 1 1 2 2 2 0 Ring hydroxylating beta subunit Fungal_trans PF04082.18 KFX98662.1 - 1e-09 37.8 0.2 3.2e-09 36.2 0.2 1.9 1 1 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.26 KFX98662.1 - 2.4e-07 30.8 13.7 0.0021 18.4 4.1 4.5 4 0 0 4 4 4 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFX98662.1 - 7.2e-06 26.4 12.1 0.007 17.1 2.1 4.0 4 0 0 4 4 4 2 C2H2-type zinc finger SLATT_1 PF18181.1 KFX98662.1 - 0.0057 16.6 1.2 1.6 8.7 0.1 3.2 2 1 1 3 3 3 1 SMODS and SLOG-associating 2TM effector domain 1 zf-H2C2_2 PF13465.6 KFX98662.1 - 0.018 15.5 7.1 0.062 13.7 2.6 2.9 2 0 0 2 2 2 0 Zinc-finger double domain DUF4173 PF13777.6 KFX98662.1 - 0.078 12.4 1.4 0.14 11.5 1.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4173) LIM PF00412.22 KFX98662.1 - 0.087 13.1 4.5 0.2 11.9 4.5 1.6 1 0 0 1 1 1 0 LIM domain HxlR PF01638.17 KFX98662.1 - 0.22 11.4 1.6 24 4.9 0.1 2.7 2 0 0 2 2 2 0 HxlR-like helix-turn-helix zf-LYAR PF08790.11 KFX98662.1 - 1.8 8.6 4.5 9.6 6.2 0.2 2.6 2 0 0 2 2 2 0 LYAR-type C2HC zinc finger COesterase PF00135.28 KFX98663.1 - 2.9e-56 191.4 0.0 4e-56 191.0 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KFX98663.1 - 2.7e-08 33.9 0.4 3.6e-07 30.3 0.4 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 KFX98663.1 - 0.0062 15.5 0.7 0.031 13.2 0.7 1.8 1 1 0 1 1 1 1 Steryl acetyl hydrolase Peptidase_S9 PF00326.21 KFX98663.1 - 0.011 15.2 0.0 0.018 14.5 0.0 1.2 1 0 0 1 1 1 0 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 KFX98663.1 - 0.14 11.4 0.1 0.47 9.7 0.0 1.8 2 0 0 2 2 2 0 Serine aminopeptidase, S33 Esterase PF00756.20 KFX98663.1 - 0.15 11.7 0.1 0.46 10.1 0.1 1.8 1 1 0 1 1 1 0 Putative esterase Leuk-A4-hydro_C PF09127.11 KFX98663.1 - 0.22 11.6 0.0 0.46 10.6 0.0 1.5 1 0 0 1 1 1 0 Leukotriene A4 hydrolase, C-terminal CMD PF02627.20 KFX98664.1 - 1.4e-11 44.3 0.0 7.6e-09 35.5 0.0 2.2 2 0 0 2 2 2 2 Carboxymuconolactone decarboxylase family TRI12 PF06609.13 KFX98665.1 - 3.1e-23 82.1 24.1 9.4e-23 80.5 24.1 1.6 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.16 KFX98665.1 - 1.1e-20 73.9 43.2 2.2e-20 72.9 37.9 2.8 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KFX98665.1 - 4.7e-07 29.0 7.5 4.7e-07 29.0 7.5 2.7 2 1 0 2 2 2 1 Sugar (and other) transporter DUF1772 PF08592.11 KFX98665.1 - 0.00045 20.5 0.1 0.00045 20.5 0.1 5.1 3 1 1 5 5 5 1 Domain of unknown function (DUF1772) TMEM220 PF15071.6 KFX98665.1 - 0.084 13.6 0.4 0.084 13.6 0.4 3.2 5 1 0 5 5 5 0 Transmembrane family 220, helix Pox_A14 PF05767.12 KFX98665.1 - 0.094 12.9 0.4 0.63 10.2 0.0 2.6 3 0 0 3 3 3 0 Poxvirus virion envelope protein A14 Saf_2TM PF18303.1 KFX98665.1 - 0.11 12.1 0.9 0.94 9.1 0.0 2.5 2 0 0 2 2 2 0 SAVED-fused 2TM effector domain RseC_MucC PF04246.12 KFX98665.1 - 0.21 11.5 0.1 0.21 11.5 0.1 4.1 6 1 1 7 7 7 0 Positive regulator of sigma(E), RseC/MucC Fungal_trans PF04082.18 KFX98667.1 - 2.4e-06 26.8 0.1 4.5e-06 25.9 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain MFS_1 PF07690.16 KFX98668.1 - 2.1e-31 109.1 52.6 5.9e-31 107.7 52.6 1.9 1 1 0 1 1 1 1 Major Facilitator Superfamily SLATT_fungal PF18142.1 KFX98668.1 - 7.3 6.6 6.7 1 9.4 1.5 2.4 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain Glyco_hydro_3_C PF01915.22 KFX98669.1 - 6.4e-29 101.4 0.0 1e-28 100.7 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Beta-lactamase PF00144.24 KFX98669.1 - 0.00056 19.3 0.7 0.0013 18.0 0.1 1.8 2 0 0 2 2 2 1 Beta-lactamase Glyco_hydro_3 PF00933.21 KFX98670.1 - 1.4e-36 126.5 0.0 2.9e-36 125.5 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.22 KFX98670.1 - 0.0011 19.0 0.0 0.0021 18.0 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Sugar_tr PF00083.24 KFX98671.1 - 1.8e-114 383.1 26.4 2.9e-114 382.4 26.4 1.3 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KFX98671.1 - 1.2e-25 90.2 57.0 8.6e-19 67.7 21.5 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Glyco_hydro_3_C PF01915.22 KFX98672.1 - 4.6e-39 134.5 0.0 6.8e-39 133.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 KFX98672.1 - 3.3e-38 131.9 0.0 6.1e-38 131.0 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 KFX98672.1 - 6.1e-21 74.3 0.0 1.2e-20 73.4 0.0 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain GFO_IDH_MocA PF01408.22 KFX98673.1 - 6.6e-21 75.4 0.2 1.5e-20 74.3 0.2 1.5 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold NAD_binding_3 PF03447.16 KFX98673.1 - 0.099 13.3 0.4 2.9 8.6 0.1 2.4 2 0 0 2 2 2 0 Homoserine dehydrogenase, NAD binding domain Fungal_trans PF04082.18 KFX98674.1 - 1.9e-21 76.3 0.0 2.6e-21 75.9 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KFX98674.1 - 1.6 8.9 13.7 3.1 8.0 13.7 1.4 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain GFO_IDH_MocA PF01408.22 KFX98675.1 - 5.7e-21 75.6 0.1 8.5e-21 75.0 0.1 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 KFX98675.1 - 1.8e-13 50.5 0.0 3.8e-13 49.5 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain NAD_binding_3 PF03447.16 KFX98675.1 - 0.00011 22.8 0.4 0.00027 21.6 0.4 1.6 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain DapB_N PF01113.20 KFX98675.1 - 0.00052 20.1 0.1 0.002 18.2 0.0 1.9 2 0 0 2 2 2 1 Dihydrodipicolinate reductase, N-terminus LysR_substrate PF03466.20 KFX98675.1 - 0.0019 17.6 0.0 0.0032 16.9 0.0 1.3 1 0 0 1 1 1 1 LysR substrate binding domain OCD_Mu_crystall PF02423.15 KFX98675.1 - 0.0043 16.0 0.0 0.0083 15.1 0.0 1.4 1 0 0 1 1 1 1 Ornithine cyclodeaminase/mu-crystallin family Semialdhyde_dh PF01118.24 KFX98675.1 - 0.005 17.3 0.0 0.0094 16.4 0.0 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Mac PF12464.8 KFX98676.1 - 8.7e-14 51.5 0.1 1.5e-13 50.8 0.1 1.4 1 0 0 1 1 1 1 Maltose acetyltransferase Hexapep PF00132.24 KFX98676.1 - 1e-13 50.4 5.8 7.6e-11 41.3 3.9 3.3 3 0 0 3 3 3 2 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 KFX98676.1 - 3.2e-13 49.2 4.5 5e-10 39.0 3.8 3.1 3 0 0 3 3 3 2 Hexapeptide repeat of succinyl-transferase DUF4413 PF14372.6 KFX98676.1 - 0.2 12.0 0.2 0.29 11.5 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4413) Sugar_tr PF00083.24 KFX98677.1 - 5.8e-87 292.4 15.6 6.7e-87 292.2 15.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KFX98677.1 - 1.7e-10 40.3 43.0 1.3e-08 34.2 31.8 2.6 1 1 2 3 3 3 2 Major Facilitator Superfamily YjcZ_2 PF09680.10 KFX98677.1 - 0.4 10.4 4.7 1.1 8.9 4.7 1.8 1 0 0 1 1 1 0 Family of unknown function Glyco_transf_21 PF13506.6 KFX98678.1 - 5.3e-07 29.3 0.0 9.7e-07 28.4 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 21 Glyco_tranf_2_3 PF13641.6 KFX98678.1 - 3.5e-06 27.1 0.0 5.8e-06 26.4 0.0 1.3 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 KFX98678.1 - 0.00021 21.1 0.0 0.0046 16.8 0.0 2.1 2 0 0 2 2 2 1 Glycosyl transferase family 2 tRNA_int_endo PF01974.17 KFX98679.1 - 9.6e-20 70.4 0.3 2.3e-19 69.2 0.3 1.6 1 1 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain tRNA_int_endo_N PF02778.14 KFX98679.1 - 0.00018 21.1 0.0 0.046 13.4 0.0 2.5 2 0 0 2 2 2 2 tRNA intron endonuclease, N-terminal domain An_peroxidase PF03098.15 KFX98680.1 - 8.4e-41 140.1 0.0 1.3e-28 99.9 0.0 3.1 1 1 1 2 2 2 2 Animal haem peroxidase p450 PF00067.22 KFX98680.1 - 1.6e-11 43.6 0.0 1e-07 31.1 0.0 2.1 2 0 0 2 2 2 2 Cytochrome P450 EXS PF03124.14 KFX98681.1 - 1.1e-101 340.5 27.3 1.3e-101 340.2 27.3 1.1 1 0 0 1 1 1 1 EXS family SPX PF03105.19 KFX98681.1 - 8.7e-81 272.8 2.1 8.7e-81 272.8 2.1 2.2 2 0 0 2 2 2 1 SPX domain Paramyx_P_V_C PF03210.13 KFX98681.1 - 0.028 14.2 0.1 0.062 13.1 0.1 1.5 1 0 0 1 1 1 0 Paramyxovirus P/V phosphoprotein C-terminal DUF936 PF06075.12 KFX98681.1 - 0.64 8.9 6.3 1.3 7.8 6.3 1.4 1 0 0 1 1 1 0 Plant protein of unknown function (DUF936) Lipase_GDSL_2 PF13472.6 KFX98682.1 - 2.9e-16 60.4 3.2 3.6e-16 60.1 3.2 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 KFX98682.1 - 7.2e-09 35.9 0.2 9.1e-09 35.6 0.2 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase 2-Hacid_dh_C PF02826.19 KFX98683.1 - 1.1e-39 135.7 0.0 1.5e-39 135.2 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 KFX98683.1 - 1.4e-10 40.9 0.0 2e-10 40.5 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 KFX98683.1 - 3e-09 37.2 0.1 1.1e-08 35.4 0.1 1.8 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.17 KFX98683.1 - 8.8e-05 23.0 0.1 0.00016 22.2 0.1 1.5 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent GFO_IDH_MocA PF01408.22 KFX98683.1 - 0.0035 18.1 0.0 0.0091 16.8 0.0 1.7 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold Radical_SAM PF04055.21 KFX98683.1 - 0.039 14.3 0.0 0.16 12.3 0.0 2.0 2 0 0 2 2 2 0 Radical SAM superfamily IlvN PF07991.12 KFX98683.1 - 0.06 12.9 0.0 0.096 12.3 0.0 1.2 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain AlaDh_PNT_C PF01262.21 KFX98683.1 - 0.12 11.7 0.0 0.2 10.9 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain NmrA PF05368.13 KFX98684.1 - 2e-18 66.8 0.1 2.6e-18 66.4 0.1 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KFX98684.1 - 7.6e-08 32.5 0.0 5.2e-07 29.7 0.0 2.0 2 0 0 2 2 2 1 NAD(P)H-binding Epimerase PF01370.21 KFX98684.1 - 0.00072 19.1 0.0 0.0054 16.2 0.0 2.0 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family KR PF08659.10 KFX98684.1 - 0.0029 17.5 0.0 0.0047 16.9 0.0 1.5 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 KFX98684.1 - 0.062 12.4 0.2 0.15 11.2 0.0 1.6 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein adh_short PF00106.25 KFX98684.1 - 0.12 11.8 0.0 0.2 11.1 0.0 1.3 1 0 0 1 1 1 0 short chain dehydrogenase IPP-2 PF04979.14 KFX98685.1 - 1.3e-22 80.9 6.1 3.1e-22 79.7 6.1 1.6 1 0 0 1 1 1 1 Protein phosphatase inhibitor 2 (IPP-2) CENP-C_C PF11699.8 KFX98686.1 - 0.00042 20.5 0.0 0.00094 19.3 0.0 1.6 1 0 0 1 1 1 1 Mif2/CENP-C like Cupin_3 PF05899.12 KFX98686.1 - 0.0034 17.1 0.3 0.0097 15.6 0.1 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF861) zf-C2H2_6 PF13912.6 KFX98686.1 - 0.004 17.1 0.4 0.013 15.5 0.4 1.9 1 0 0 1 1 1 1 C2H2-type zinc finger zf-C2H2 PF00096.26 KFX98686.1 - 0.0071 16.7 1.2 0.026 15.0 1.2 2.1 1 0 0 1 1 1 1 Zinc finger, C2H2 type Cupin_2 PF07883.11 KFX98686.1 - 0.035 13.8 0.1 0.11 12.3 0.1 1.8 1 0 0 1 1 1 0 Cupin domain zf-C2H2_4 PF13894.6 KFX98686.1 - 0.089 13.7 1.0 0.29 12.1 1.0 2.0 1 0 0 1 1 1 0 C2H2-type zinc finger Peptidase_M18 PF02127.15 KFX98687.1 - 2e-130 435.4 0.0 2.8e-130 435.0 0.0 1.2 1 0 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) tRNA-synt_1e PF01406.19 KFX98687.1 - 9.5e-117 389.6 0.0 1.6e-116 388.9 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1g PF09334.11 KFX98687.1 - 9.7e-06 24.6 0.0 0.14 10.9 0.0 2.5 2 0 0 2 2 2 2 tRNA synthetases class I (M) DALR_2 PF09190.11 KFX98687.1 - 8.7e-05 22.9 0.0 0.00032 21.1 0.0 2.0 1 0 0 1 1 1 1 DALR domain tRNA-synt_1f PF01921.18 KFX98687.1 - 0.02 13.8 0.0 6 5.7 0.0 2.3 2 0 0 2 2 2 0 tRNA synthetases class I (K) DUF2052 PF09747.9 KFX98687.1 - 0.053 13.6 2.1 0.097 12.8 2.1 1.3 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) tRNA-synt_1c PF00749.21 KFX98687.1 - 0.058 12.3 4.6 0.078 11.9 0.0 2.3 2 0 0 2 2 2 0 tRNA synthetases class I (E and Q), catalytic domain kleA_kleC PF17383.2 KFX98687.1 - 0.54 10.6 4.9 1.6 9.1 4.9 1.8 1 0 0 1 1 1 0 Uncharacterized KorC regulated protein A GCD14 PF08704.10 KFX98688.1 - 4.6e-63 213.2 0.3 3.5e-43 148.0 0.0 2.6 1 1 1 2 2 2 2 tRNA methyltransferase complex GCD14 subunit DUF3736 PF12540.8 KFX98688.1 - 0.025 14.7 2.4 0.081 13.0 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3736) DUF3759 PF12585.8 KFX98689.1 - 4.3e-37 126.0 9.4 6.5e-37 125.5 9.4 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3759) DUF3824 PF12868.7 KFX98689.1 - 2.1 9.0 13.2 3.1 8.4 10.3 2.3 1 1 1 2 2 2 0 Domain of unknwon function (DUF3824) DNA_pol_lambd_f PF10391.9 KFX98693.1 - 2.9e-21 75.0 0.4 8e-21 73.6 0.4 1.8 1 0 0 1 1 1 1 Fingers domain of DNA polymerase lambda DNA_pol_B_thumb PF14791.6 KFX98693.1 - 2.7e-20 72.3 0.1 4.8e-20 71.5 0.1 1.4 1 0 0 1 1 1 1 DNA polymerase beta thumb DNA_pol_B_palm PF14792.6 KFX98693.1 - 8.7e-20 71.0 0.0 1.6e-19 70.2 0.0 1.4 1 1 0 1 1 1 1 DNA polymerase beta palm HHH_8 PF14716.6 KFX98693.1 - 4.7e-07 30.1 0.0 1.1e-06 29.0 0.0 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix domain HHH_5 PF14520.6 KFX98693.1 - 0.019 15.6 0.0 0.34 11.6 0.0 2.7 3 0 0 3 3 3 0 Helix-hairpin-helix domain Ecl1 PF12855.7 KFX98694.1 - 1.1e-19 72.3 9.2 1.3e-19 72.0 9.2 1.1 1 0 0 1 1 1 1 ECL1/2/3 zinc binding proteins YacG PF03884.14 KFX98694.1 - 0.16 11.7 2.0 0.33 10.7 2.0 1.5 1 0 0 1 1 1 0 DNA gyrase inhibitor YacG zf-FLZ PF04570.14 KFX98694.1 - 0.21 11.1 5.5 2.5 7.6 5.5 2.2 1 1 0 1 1 1 0 zinc-finger of the FCS-type, C2-C2 SOG2 PF10428.9 KFX98699.1 - 0.52 9.4 8.4 0.57 9.3 8.4 1.0 1 0 0 1 1 1 0 RAM signalling pathway protein DUF5558 PF17713.1 KFX98699.1 - 2.5 8.5 7.4 0.35 11.3 2.7 1.9 2 1 0 2 2 2 0 Family of unknown function (DUF5558) RRM_1 PF00076.22 KFX98715.1 - 2.6e-12 46.4 0.0 3.9e-12 45.8 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CSD PF00313.22 KFX98715.1 - 0.0024 17.7 0.1 0.0064 16.3 0.1 1.8 2 1 0 2 2 2 1 'Cold-shock' DNA-binding domain DUF3471 PF11954.8 KFX98715.1 - 0.11 13.0 0.1 7.4 7.1 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3471) RRM_occluded PF16842.5 KFX98715.1 - 0.11 12.3 0.0 0.16 11.9 0.0 1.2 1 0 0 1 1 1 0 Occluded RNA-recognition motif RRM_7 PF16367.5 KFX98715.1 - 0.17 12.0 0.0 0.4 10.8 0.0 1.6 1 1 1 2 2 2 0 RNA recognition motif Ndc80_HEC PF03801.13 KFX98716.1 - 8.4e-43 145.6 1.0 1.9e-42 144.5 1.0 1.6 1 0 0 1 1 1 1 HEC/Ndc80p family Tropomyosin PF00261.20 KFX98716.1 - 1.4e-06 27.9 15.2 1.4e-06 27.9 15.2 3.3 2 1 1 3 3 3 2 Tropomyosin FliJ PF02050.16 KFX98716.1 - 0.00094 19.4 25.2 0.039 14.2 5.6 3.5 2 1 0 2 2 2 2 Flagellar FliJ protein Filament PF00038.21 KFX98716.1 - 0.0012 18.5 42.7 0.0094 15.6 21.6 3.1 2 1 0 2 2 2 2 Intermediate filament protein WASH_WAHD PF11945.8 KFX98716.1 - 0.44 10.0 10.1 0.029 13.9 1.3 2.6 3 0 0 3 3 3 0 WAHD domain of WASH complex TPR_MLP1_2 PF07926.12 KFX98716.1 - 0.55 10.3 42.5 0.046 13.8 11.9 3.9 2 2 1 3 3 3 0 TPR/MLP1/MLP2-like protein APG6_N PF17675.1 KFX98716.1 - 0.59 10.7 50.7 0.053 14.0 5.4 4.4 2 1 2 4 4 4 0 Apg6 coiled-coil region NPV_P10 PF05531.12 KFX98716.1 - 1.2 9.6 11.2 1.1 9.8 1.1 4.2 3 2 1 4 4 4 0 Nucleopolyhedrovirus P10 protein Golgin_A5 PF09787.9 KFX98716.1 - 3 7.2 44.0 0.96 8.9 13.9 3.7 2 2 2 4 4 4 0 Golgin subfamily A member 5 DUF4407 PF14362.6 KFX98716.1 - 3.7 6.8 25.0 0.47 9.7 4.9 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF4407) FtsL PF04999.13 KFX98716.1 - 4 7.5 10.2 2.1 8.4 0.3 3.2 3 0 0 3 3 3 0 Cell division protein FtsL MtrG PF04210.13 KFX98716.1 - 6.6 6.7 5.1 9.7 6.1 0.1 3.5 3 0 0 3 3 3 0 Tetrahydromethanopterin S-methyltransferase, subunit G Strep_SA_rep PF06696.11 KFX98716.1 - 7.1 6.8 6.8 89 3.3 0.1 4.0 4 0 0 4 4 4 0 Streptococcal surface antigen repeat PI-PLC-X PF00388.19 KFX98723.1 - 9.7e-51 171.2 0.0 1.5e-50 170.6 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.19 KFX98723.1 - 2.1e-37 128.0 0.0 4e-37 127.1 0.0 1.5 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain TYW3 PF02676.14 KFX98723.1 - 0.022 14.2 0.1 0.038 13.3 0.1 1.3 1 0 0 1 1 1 0 Methyltransferase TYW3 MCPVI PF02993.14 KFX98723.1 - 0.032 14.1 2.1 12 5.7 0.0 2.5 3 0 0 3 3 3 0 Minor capsid protein VI DUF4666 PF15697.5 KFX98723.1 - 0.13 12.9 4.1 7.7 7.2 1.2 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4666) CAF1 PF04857.20 KFX98740.1 - 1.5e-18 67.0 0.0 4.4e-08 32.7 0.0 2.1 2 0 0 2 2 2 2 CAF1 family ribonuclease RFX_DNA_binding PF02257.15 KFX98740.1 - 0.073 13.7 0.0 0.18 12.5 0.0 1.6 1 0 0 1 1 1 0 RFX DNA-binding domain DUF155 PF02582.14 KFX98741.1 - 4.8e-53 179.9 0.3 6.4e-53 179.4 0.3 1.2 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 UPF0449 PF15136.6 KFX98741.1 - 0.015 15.7 0.0 0.033 14.7 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised protein family UPF0449 Sugar_tr PF00083.24 KFX98742.1 - 3.9e-68 230.4 22.5 4.4e-68 230.2 22.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KFX98742.1 - 8.2e-07 28.3 38.1 1.2e-06 27.7 33.1 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Fmp27 PF10344.9 KFX98743.1 - 4e-207 690.3 0.0 6.3e-207 689.6 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial protein from FMP27 Apt1 PF10351.9 KFX98743.1 - 8.8e-202 671.2 5.8 8.8e-202 671.2 5.8 3.5 4 0 0 4 4 4 1 Golgi-body localisation protein domain Fmp27_WPPW PF10359.9 KFX98743.1 - 2e-179 597.5 0.0 3.4e-179 596.8 0.0 1.4 1 0 0 1 1 1 1 RNA pol II promoter Fmp27 protein domain DUF2405 PF10293.9 KFX98743.1 - 3.2e-57 192.8 0.1 8.3e-57 191.4 0.1 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF2405) Fmp27_GFWDK PF10347.9 KFX98743.1 - 1.2e-55 187.9 0.0 2.8e-55 186.7 0.0 1.7 1 0 0 1 1 1 1 RNA pol II promoter Fmp27 protein domain Fmp27_SW PF10305.9 KFX98743.1 - 9.5e-33 113.0 0.0 9.5e-33 113.0 0.0 2.9 3 0 0 3 3 3 1 RNA pol II promoter Fmp27 protein domain Serine_rich PF08824.10 KFX98743.1 - 0.11 12.5 0.0 0.32 11.0 0.0 1.8 1 0 0 1 1 1 0 Serine rich protein interaction domain RRM_1 PF00076.22 KFX98744.1 - 3.3e-08 33.2 0.0 5.4e-08 32.5 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Tombus_movement PF05318.12 KFX98744.1 - 0.41 11.5 6.2 2.2 9.2 6.2 2.3 1 0 0 1 1 1 0 Tombusvirus movement protein PTS_2-RNA PF01885.16 KFX98775.1 - 4.6e-22 78.9 0.2 5.3e-22 78.7 0.2 1.0 1 0 0 1 1 1 1 RNA 2'-phosphotransferase, Tpt1 / KptA family CDT1 PF08839.11 KFX98775.1 - 0.06 13.6 0.0 0.077 13.3 0.0 1.1 1 0 0 1 1 1 0 DNA replication factor CDT1 like FoP_duplication PF13865.6 KFX98775.1 - 0.87 10.2 8.4 1.3 9.6 8.4 1.2 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 Aldo_ket_red PF00248.21 KFX98776.1 - 1.6e-50 172.0 0.0 1.9e-50 171.7 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Med1 PF10744.9 KFX98779.1 - 1.9e-108 363.2 0.0 3.7e-108 362.2 0.0 1.4 2 0 0 2 2 2 1 Mediator of RNA polymerase II transcription subunit 1 RNA_pol_Rpb1_R PF05001.13 KFX98780.1 - 7.7 7.1 7.2 45 4.7 2.5 3.5 2 0 0 2 2 2 0 RNA polymerase Rpb1 C-terminal repeat Glyco_tranf_2_4 PF13704.6 KFX98783.1 - 4.6e-07 30.3 0.2 1.9e-06 28.3 0.1 2.0 2 0 0 2 2 2 1 Glycosyl transferase family 2 Glyco_transf_92 PF01697.27 KFX98783.1 - 1.9e-06 27.7 0.4 4.6e-06 26.5 0.4 1.6 1 1 0 1 1 1 1 Glycosyltransferase family 92 LysM PF01476.20 KFX98786.1 - 3e-05 24.0 0.0 0.47 10.6 0.0 3.7 4 0 0 4 4 4 3 LysM domain ETF_QO PF05187.13 KFX98788.1 - 5.1e-48 161.5 0.1 8.5e-48 160.8 0.1 1.4 1 0 0 1 1 1 1 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S Fer4_7 PF12838.7 KFX98788.1 - 0.0097 16.5 1.1 0.021 15.4 1.1 1.6 1 0 0 1 1 1 1 4Fe-4S dicluster domain Pyr_redox PF00070.27 KFX98788.1 - 0.1 13.2 0.0 0.52 10.9 0.0 2.1 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Fer4_2 PF12797.7 KFX98788.1 - 0.12 12.6 0.7 0.31 11.2 0.7 1.6 1 0 0 1 1 1 0 4Fe-4S binding domain DUF676 PF05057.14 KFX98790.1 - 2e-49 168.1 0.0 2.9e-49 167.5 0.0 1.2 1 0 0 1 1 1 1 Putative serine esterase (DUF676) PGAP1 PF07819.13 KFX98790.1 - 6.2e-05 22.8 0.0 0.00048 19.9 0.0 2.0 1 1 0 1 1 1 1 PGAP1-like protein Palm_thioest PF02089.15 KFX98790.1 - 0.00084 19.3 0.0 0.0012 18.7 0.0 1.2 1 0 0 1 1 1 1 Palmitoyl protein thioesterase Abhydrolase_6 PF12697.7 KFX98790.1 - 0.067 13.8 0.0 0.1 13.2 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family LCAT PF02450.15 KFX98790.1 - 0.12 11.5 0.0 0.19 10.9 0.0 1.2 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase CMAS PF02353.20 KFX98792.1 - 2.5e-59 200.8 0.0 3.2e-59 200.5 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_23 PF13489.6 KFX98792.1 - 1.5e-12 47.7 0.0 2.5e-12 46.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KFX98792.1 - 3.6e-10 40.3 0.0 8.4e-10 39.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KFX98792.1 - 5.7e-10 39.8 0.0 1.4e-09 38.5 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KFX98792.1 - 0.00032 20.5 0.0 0.00081 19.2 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KFX98792.1 - 0.0015 19.3 0.0 0.0041 17.8 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain DOT1 PF08123.13 KFX98792.1 - 0.012 15.2 0.0 0.019 14.5 0.0 1.2 1 0 0 1 1 1 0 Histone methylation protein DOT1 PCMT PF01135.19 KFX98792.1 - 0.015 15.0 0.0 0.027 14.2 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MTS PF05175.14 KFX98792.1 - 0.026 14.1 0.0 0.046 13.3 0.0 1.4 1 1 0 1 1 1 0 Methyltransferase small domain FtsJ PF01728.19 KFX98792.1 - 0.19 11.8 0.0 0.39 10.8 0.0 1.5 1 1 0 1 1 1 0 FtsJ-like methyltransferase EF-hand_4 PF12763.7 KFX98793.1 - 3.7e-25 87.9 0.0 5.7e-12 45.5 0.0 2.5 2 0 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand WH2 PF02205.20 KFX98793.1 - 1.4e-06 27.9 0.3 3.6e-06 26.6 0.3 1.8 1 0 0 1 1 1 1 WH2 motif EF-hand_1 PF00036.32 KFX98793.1 - 0.0034 16.8 0.0 3.3 7.5 0.0 2.5 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 KFX98793.1 - 0.0066 16.9 0.3 7 7.2 0.0 3.1 3 0 0 3 3 3 2 EF-hand domain pair E3_binding PF02817.17 KFX98793.1 - 0.073 13.4 0.0 0.21 12.0 0.0 1.8 1 0 0 1 1 1 0 e3 binding domain RAMP4 PF06624.12 KFX98795.1 - 6.4e-23 80.6 0.6 8e-23 80.3 0.6 1.1 1 0 0 1 1 1 1 Ribosome associated membrane protein RAMP4 Adaptin_N PF01602.20 KFX98796.1 - 2.2e-79 267.4 0.0 3.2e-79 266.9 0.0 1.2 1 0 0 1 1 1 1 Adaptin N terminal region SMAP PF15477.6 KFX98796.1 - 4.3e-13 50.0 1.5 4.3e-13 50.0 1.5 4.6 3 1 0 3 3 3 1 Small acidic protein family Cnd1 PF12717.7 KFX98796.1 - 7.7e-05 22.8 0.1 0.00074 19.6 0.0 2.5 3 0 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 TPR_19 PF14559.6 KFX98797.1 - 5.7e-08 33.2 1.0 0.0014 19.1 0.6 3.7 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 KFX98797.1 - 2.1e-06 27.4 1.0 0.0031 17.5 0.1 5.0 6 0 0 6 6 5 1 Tetratricopeptide repeat TPR_11 PF13414.6 KFX98797.1 - 3.4e-06 26.6 0.1 0.011 15.4 0.0 3.7 3 1 1 4 4 4 2 TPR repeat TPR_14 PF13428.6 KFX98797.1 - 5.2e-06 26.8 7.7 0.0082 16.9 0.4 5.4 3 1 3 6 6 5 2 Tetratricopeptide repeat TPR_17 PF13431.6 KFX98797.1 - 7.6e-06 25.9 0.1 0.015 15.6 0.0 4.1 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_8 PF13181.6 KFX98797.1 - 7.7e-05 22.6 0.0 0.0037 17.4 0.1 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.6 KFX98797.1 - 0.0013 19.3 1.7 0.0049 17.5 0.7 3.4 2 1 3 5 5 5 2 Tetratricopeptide repeat TPR_9 PF13371.6 KFX98797.1 - 0.0052 16.9 1.4 0.011 15.8 0.2 2.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.6 KFX98797.1 - 0.0082 16.4 2.9 25 5.2 0.7 4.9 4 1 0 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.6 KFX98797.1 - 0.0086 16.7 2.1 8.9 7.2 0.0 4.7 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_1 PF00515.28 KFX98797.1 - 0.033 14.0 0.0 4.6 7.2 0.0 3.1 2 0 0 2 2 2 0 Tetratricopeptide repeat Wzy_C_2 PF11846.8 KFX98797.1 - 0.064 13.2 0.0 2.4 8.0 0.0 2.2 1 1 1 2 2 2 0 Virulence factor membrane-bound polymerase, C-terminal TPR_20 PF14561.6 KFX98797.1 - 0.11 12.9 1.0 0.69 10.3 0.1 2.6 2 1 0 2 2 2 0 Tetratricopeptide repeat Ada_Zn_binding PF02805.16 KFX98801.1 - 1.4e-30 105.1 3.7 2.3e-30 104.4 3.7 1.3 1 0 0 1 1 1 1 Metal binding domain of Ada HTH_AraC PF00165.23 KFX98801.1 - 1.1e-07 31.7 0.0 2.8e-07 30.4 0.0 1.7 1 0 0 1 1 1 1 Bacterial regulatory helix-turn-helix proteins, AraC family HTH_18 PF12833.7 KFX98801.1 - 0.00061 20.0 0.0 0.0014 18.9 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain DNA_binding_1 PF01035.20 KFX98802.1 - 4.1e-25 87.7 0.0 5e-25 87.4 0.0 1.1 1 0 0 1 1 1 1 6-O-methylguanine DNA methyltransferase, DNA binding domain Helo_like_N PF17111.5 KFX98803.1 - 2.2e-05 24.0 0.2 4e-05 23.1 0.2 1.3 1 0 0 1 1 1 1 Fungal N-terminal domain of STAND proteins SesA PF17107.5 KFX98803.1 - 0.027 14.6 0.0 0.094 12.9 0.0 1.9 2 0 0 2 2 2 0 N-terminal domain on NACHT_NTPase and P-loop NTPases Utp8 PF10395.9 KFX98804.1 - 6.4e-19 67.9 0.2 9.6e-15 54.1 0.0 2.9 2 1 0 2 2 2 2 Utp8 family AAA PF00004.29 KFX98805.1 - 1.5e-09 38.4 0.9 3.6e-08 33.9 0.9 2.4 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 KFX98805.1 - 4.4e-07 30.0 1.3 0.00039 20.4 0.0 3.2 3 0 0 3 3 3 1 Rad17 P-loop domain AAA_16 PF13191.6 KFX98805.1 - 0.00023 21.6 0.0 0.00051 20.5 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 KFX98805.1 - 0.0025 18.1 0.1 0.016 15.5 0.1 2.2 1 1 0 1 1 1 1 AAA domain NTPase_1 PF03266.15 KFX98805.1 - 0.0077 16.2 0.0 0.93 9.4 0.0 2.3 2 0 0 2 2 2 1 NTPase AAA_18 PF13238.6 KFX98805.1 - 0.0092 16.5 0.1 0.025 15.1 0.1 1.7 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.6 KFX98805.1 - 0.055 13.5 0.0 0.12 12.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain RuvB_N PF05496.12 KFX98805.1 - 0.079 12.7 0.0 0.17 11.7 0.0 1.5 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain TIP49 PF06068.13 KFX98805.1 - 0.1 11.8 0.0 0.17 11.0 0.0 1.2 1 0 0 1 1 1 0 TIP49 P-loop domain AAA_28 PF13521.6 KFX98805.1 - 0.1 12.8 0.0 0.2 11.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain ATPase_2 PF01637.18 KFX98805.1 - 0.1 12.5 0.0 0.2 11.6 0.0 1.5 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea RNA_helicase PF00910.22 KFX98805.1 - 0.11 13.0 0.0 0.29 11.5 0.0 1.8 1 0 0 1 1 1 0 RNA helicase AAA_33 PF13671.6 KFX98805.1 - 0.13 12.4 0.0 0.4 10.8 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 KFX98805.1 - 0.58 10.6 5.1 0.42 11.1 2.1 2.3 2 1 0 2 2 2 0 AAA domain SGL PF08450.12 KFX98811.1 - 1.7e-61 208.0 0.0 2e-61 207.7 0.0 1.1 1 0 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region ParcG PF10274.9 KFX98811.1 - 0.0045 17.1 0.0 0.0071 16.5 0.0 1.2 1 0 0 1 1 1 1 Parkin co-regulated protein Arylesterase PF01731.20 KFX98811.1 - 0.015 15.5 0.0 0.038 14.2 0.0 1.7 1 0 0 1 1 1 0 Arylesterase Phytase-like PF13449.6 KFX98811.1 - 0.095 12.6 0.0 0.69 9.8 0.0 2.1 2 1 1 3 3 3 0 Esterase-like activity of phytase Reg_prop PF07494.11 KFX98811.1 - 0.13 12.6 4.8 4.2 7.9 0.1 4.0 3 0 0 3 3 3 0 Two component regulator propeller adh_short_C2 PF13561.6 KFX98812.1 - 2.1e-60 204.2 0.3 2.5e-60 204.0 0.3 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KFX98812.1 - 5.6e-47 159.7 1.3 6.6e-47 159.5 1.3 1.0 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KFX98812.1 - 5.6e-13 49.2 0.3 8.1e-13 48.7 0.3 1.2 1 0 0 1 1 1 1 KR domain Fungal_trans PF04082.18 KFX98813.1 - 3.8e-29 101.5 0.2 3.8e-29 101.5 0.2 1.5 2 0 0 2 2 2 1 Fungal specific transcription factor domain DHDPS PF00701.22 KFX98813.1 - 1.7e-08 33.5 0.0 2.7e-08 32.9 0.0 1.2 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family Zn_clus PF00172.18 KFX98813.1 - 7.2e-07 29.2 10.4 1.5e-06 28.2 10.4 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DHDPS PF00701.22 KFX98814.1 - 1.9e-06 26.8 0.0 2e-06 26.7 0.0 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family MR_MLE_C PF13378.6 KFX98815.1 - 5e-55 186.4 0.0 7e-55 186.0 0.0 1.1 1 0 0 1 1 1 1 Enolase C-terminal domain-like Aldose_epim PF01263.20 KFX98815.1 - 2e-22 79.9 0.0 3.1e-22 79.3 0.0 1.2 1 0 0 1 1 1 1 Aldose 1-epimerase MR_MLE_N PF02746.16 KFX98815.1 - 3.8e-16 59.4 0.0 8.5e-16 58.2 0.0 1.6 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain Sugar_tr PF00083.24 KFX98816.1 - 6e-89 299.0 21.6 6.9e-89 298.8 21.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KFX98816.1 - 9.5e-41 139.9 42.2 3.7e-35 121.5 23.4 1.4 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF389 PF04087.14 KFX98816.1 - 0.17 11.9 6.4 0.039 14.0 1.7 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF389) DUF3792 PF12670.7 KFX98816.1 - 3.6 7.8 18.7 0.31 11.2 5.8 3.0 2 1 0 2 2 2 0 Protein of unknown function (DUF3792) Lipase_GDSL_2 PF13472.6 KFX98817.1 - 3.9e-10 40.4 0.3 5.1e-10 40.0 0.3 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Glyco_hydro_2_C PF02836.17 KFX98818.1 - 4.7e-103 344.4 0.0 7e-103 343.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Bgal_small_N PF02929.17 KFX98818.1 - 2.4e-65 220.6 0.0 3.5e-65 220.0 0.0 1.3 1 0 0 1 1 1 1 Beta galactosidase small chain Glyco_hydro_2_N PF02837.18 KFX98818.1 - 1e-42 145.9 1.0 2.2e-42 144.9 1.0 1.6 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain DUF4981 PF16353.5 KFX98818.1 - 2.8e-20 72.6 0.0 7.1e-20 71.3 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function(DUF4981) Glyco_hydro_2 PF00703.21 KFX98818.1 - 5.5e-10 39.9 0.7 1.9e-09 38.2 0.0 2.3 3 0 0 3 3 3 1 Glycosyl hydrolases family 2 Glyco_hydro_42 PF02449.15 KFX98818.1 - 0.018 14.4 0.1 0.034 13.5 0.1 1.3 1 0 0 1 1 1 0 Beta-galactosidase PhyH PF05721.13 KFX98819.1 - 2.3e-11 44.4 0.0 4.3e-11 43.5 0.0 1.4 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) Glyco_hydro_43 PF04616.14 KFX98820.1 - 1.4e-09 37.7 7.0 5.3e-09 35.8 2.7 1.6 1 1 1 2 2 2 2 Glycosyl hydrolases family 43 Aldo_ket_red PF00248.21 KFX98821.1 - 5.7e-65 219.4 0.0 6.6e-65 219.2 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Glyco_hydro2_C5 PF18565.1 KFX98822.1 - 1.1e-31 108.8 0.2 1.8e-31 108.0 0.2 1.4 1 0 0 1 1 1 1 Glycoside hydrolase family 2 C-terminal domain 5 Glyco_hydro_2_C PF02836.17 KFX98822.1 - 1.7e-24 86.5 0.0 3.6e-24 85.4 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain DUF4982 PF16355.5 KFX98822.1 - 8e-21 73.7 0.1 2e-20 72.5 0.1 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4982) Glyco_hydro_2_N PF02837.18 KFX98822.1 - 1.1e-19 71.0 0.0 2.4e-19 69.9 0.0 1.6 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_2 PF00703.21 KFX98822.1 - 6.6e-15 55.7 0.1 1.5e-14 54.6 0.1 1.6 1 0 0 1 1 1 1 Glycosyl hydrolases family 2 Invasin_D3 PF09134.10 KFX98822.1 - 0.0002 21.6 2.7 0.0032 17.8 1.3 3.1 2 1 0 2 2 2 1 Invasin, domain 3 DUF2185 PF09951.9 KFX98822.1 - 0.12 12.2 0.0 0.29 11.0 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2185) ACP PF06857.11 KFX98822.1 - 0.13 12.5 0.2 0.4 11.0 0.2 1.8 1 0 0 1 1 1 0 Malonate decarboxylase delta subunit (MdcD) Big_1 PF02369.16 KFX98822.1 - 1.1 9.3 5.5 0.31 11.1 0.4 2.7 3 0 0 3 3 3 0 Bacterial Ig-like domain (group 1) CBM-like PF14683.6 KFX98823.1 - 6.1e-31 107.5 0.1 1.4e-30 106.4 0.1 1.6 1 0 0 1 1 1 1 Polysaccharide lyase family 4, domain III fn3_3 PF14686.6 KFX98823.1 - 3.7e-11 42.6 0.5 3.7e-11 42.6 0.5 2.3 2 0 0 2 2 2 1 Polysaccharide lyase family 4, domain II CarboxypepD_reg PF13620.6 KFX98823.1 - 1.1e-06 28.8 0.8 3.3e-06 27.3 0.8 1.8 1 0 0 1 1 1 1 Carboxypeptidase regulatory-like domain CarbopepD_reg_2 PF13715.6 KFX98823.1 - 0.009 16.0 0.6 0.052 13.6 0.1 2.6 2 1 0 2 2 2 1 CarboxypepD_reg-like domain Dirigent PF03018.14 KFX98823.1 - 0.035 13.9 0.0 0.083 12.7 0.0 1.5 1 0 0 1 1 1 0 Dirigent-like protein Pex24p PF06398.11 KFX98825.1 - 1.2e-50 172.6 0.4 1.4e-50 172.3 0.4 1.1 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin DUF3292 PF11696.8 KFX98825.1 - 0.0014 17.1 0.7 0.018 13.4 0.0 2.0 2 0 0 2 2 2 2 Protein of unknown function (DUF3292) Pkinase PF00069.25 KFX98826.1 - 6.2e-53 179.8 0.5 1.1e-52 179.0 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFX98826.1 - 1.1e-17 64.2 0.1 3e-17 62.8 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.23 KFX98826.1 - 0.16 11.9 0.0 0.34 10.8 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family ANAPC_CDC26 PF10471.9 KFX98832.1 - 2.8e-12 47.3 3.1 3.7e-12 46.9 3.1 1.2 1 0 0 1 1 1 1 Anaphase-promoting complex APC subunit CDC26 Peptidase_M1_N PF17900.1 KFX98833.1 - 0.00061 20.0 0.0 0.012 15.8 0.0 2.3 2 0 0 2 2 2 1 Peptidase M1 N-terminal domain SAS4 PF15460.6 KFX98834.1 - 6.9e-32 109.5 0.1 1.6e-31 108.4 0.1 1.6 1 0 0 1 1 1 1 Something about silencing, SAS, complex subunit 4 Adaptin_binding PF10199.9 KFX98834.1 - 0.53 10.9 8.4 0.039 14.6 2.4 2.2 2 1 0 2 2 2 0 Alpha and gamma adaptin binding protein p34 TACC_C PF05010.14 KFX98838.1 - 0.0033 17.2 0.7 0.0037 17.1 0.7 1.1 1 0 0 1 1 1 1 Transforming acidic coiled-coil-containing protein (TACC), C-terminal IFT57 PF10498.9 KFX98838.1 - 0.026 13.5 2.8 0.028 13.4 2.8 1.0 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 CENP-H PF05837.12 KFX98838.1 - 0.029 14.8 0.7 0.036 14.5 0.7 1.1 1 0 0 1 1 1 0 Centromere protein H (CENP-H) APG6_N PF17675.1 KFX98838.1 - 0.038 14.5 4.3 0.043 14.3 4.3 1.1 1 0 0 1 1 1 0 Apg6 coiled-coil region Snapin_Pallidin PF14712.6 KFX98838.1 - 0.049 14.1 3.0 0.09 13.2 1.5 1.9 1 1 0 2 2 2 0 Snapin/Pallidin BNIP2 PF12496.8 KFX98838.1 - 0.049 14.1 0.2 0.056 13.9 0.2 1.0 1 0 0 1 1 1 0 Bcl2-/adenovirus E1B nineteen kDa-interacting protein 2 DUF1664 PF07889.12 KFX98838.1 - 0.054 13.5 0.7 0.066 13.2 0.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) YojJ PF10372.9 KFX98838.1 - 0.27 11.3 1.9 0.87 9.7 0.2 2.0 1 1 1 2 2 2 0 Bacterial membrane-spanning protein N-terminus ABC2_membrane PF01061.24 KFX98847.1 - 3.1e-86 288.1 55.7 9.2e-48 162.4 23.1 2.5 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.27 KFX98847.1 - 5.4e-36 124.1 0.0 2.5e-17 63.7 0.0 2.6 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.12 KFX98847.1 - 1.8e-35 120.7 2.4 5.2e-28 96.8 0.0 3.3 3 0 0 3 3 2 2 CDR ABC transporter ABC_trans_N PF14510.6 KFX98847.1 - 8.7e-34 116.0 0.8 1.7e-19 70.2 0.1 3.1 2 1 1 3 3 2 2 ABC-transporter N-terminal AAA_16 PF13191.6 KFX98847.1 - 4.5e-07 30.4 0.2 0.0038 17.6 0.1 2.5 2 0 0 2 2 2 2 AAA ATPase domain AAA_25 PF13481.6 KFX98847.1 - 5.6e-06 26.1 0.2 4.5e-05 23.1 0.0 2.4 3 0 0 3 3 3 1 AAA domain RsgA_GTPase PF03193.16 KFX98847.1 - 6.3e-06 26.2 0.1 0.00093 19.1 0.0 2.4 2 0 0 2 2 2 1 RsgA GTPase AAA_33 PF13671.6 KFX98847.1 - 9.5e-05 22.6 0.1 0.035 14.3 0.1 2.8 2 0 0 2 2 2 1 AAA domain ABC2_membrane_3 PF12698.7 KFX98847.1 - 0.00016 20.9 7.7 0.00016 20.9 7.7 3.6 2 2 0 2 2 1 1 ABC-2 family transporter protein AAA_21 PF13304.6 KFX98847.1 - 0.00036 20.5 0.7 0.52 10.1 0.0 3.0 2 1 1 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 KFX98847.1 - 0.00054 19.7 1.4 0.051 13.3 0.2 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_18 PF13238.6 KFX98847.1 - 0.0011 19.5 0.0 0.054 14.0 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 KFX98847.1 - 0.0079 16.5 0.2 2.3 8.5 0.0 3.0 3 0 0 3 3 3 1 AAA domain SMC_N PF02463.19 KFX98847.1 - 0.0083 15.6 0.0 0.45 9.9 0.0 2.9 3 0 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_30 PF13604.6 KFX98847.1 - 0.0084 15.8 0.3 0.9 9.2 0.3 2.4 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 KFX98847.1 - 0.08 12.9 1.6 2.7 7.9 0.3 2.5 2 0 0 2 2 2 0 NACHT domain MMR_HSR1 PF01926.23 KFX98847.1 - 0.12 12.4 0.3 20 5.3 0.0 2.6 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_17 PF13207.6 KFX98847.1 - 0.13 12.7 0.3 1.5 9.2 0.0 2.3 2 0 0 2 2 2 0 AAA domain cobW PF02492.19 KFX98847.1 - 0.61 9.6 2.4 2.8 7.5 0.2 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain CTP_transf_like PF01467.26 KFX98849.1 - 2.1e-24 86.3 0.0 3.1e-24 85.8 0.0 1.3 1 0 0 1 1 1 1 Cytidylyltransferase-like Sugar_tr PF00083.24 KFX98850.1 - 6.6e-35 120.8 32.3 5.5e-21 75.0 15.7 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 KFX98850.1 - 8.2e-20 71.0 41.4 5.7e-10 38.7 26.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sec16_C PF12931.7 KFX98879.1 - 1.8e-07 31.1 0.1 5.9e-06 26.2 0.0 2.7 2 1 0 2 2 2 1 Sec23-binding domain of Sec16 SRA1 PF07304.11 KFX98879.1 - 4.4e-07 29.8 0.0 4.4e-07 29.8 0.0 4.5 5 0 0 5 5 5 1 Steroid receptor RNA activator (SRA1) WD40 PF00400.32 KFX98879.1 - 0.00012 22.8 7.0 0.023 15.6 0.0 5.5 7 0 0 7 7 7 1 WD domain, G-beta repeat PALB2_WD40 PF16756.5 KFX98879.1 - 0.0024 16.9 0.0 0.0059 15.6 0.0 1.5 1 1 0 1 1 1 1 Partner and localizer of BRCA2 WD40 domain RRM_1 PF00076.22 KFX98880.1 - 4.7e-16 58.4 0.0 7.4e-16 57.7 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KFX98880.1 - 0.0036 17.4 0.0 0.0049 17.0 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif Nup35_RRM_2 PF14605.6 KFX98880.1 - 0.11 12.6 0.0 0.19 11.7 0.0 1.4 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif B12D PF06522.11 KFX98881.1 - 0.017 14.9 0.0 0.024 14.4 0.0 1.3 1 0 0 1 1 1 0 NADH-ubiquinone reductase complex 1 MLRQ subunit Velvet PF11754.8 KFX98885.1 - 9.7e-52 176.4 0.1 1.3e-51 176.0 0.1 1.1 1 0 0 1 1 1 1 Velvet factor Fer2_3 PF13085.6 KFX98886.1 - 1.9e-30 105.1 0.0 3.1e-30 104.4 0.0 1.3 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer4_17 PF13534.6 KFX98886.1 - 4.3e-09 36.8 6.3 4.3e-09 36.8 6.3 2.1 2 1 1 3 3 3 1 4Fe-4S dicluster domain Fer4_8 PF13183.6 KFX98886.1 - 1.1e-07 32.2 8.6 1.1e-07 32.2 8.6 2.3 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_10 PF13237.6 KFX98886.1 - 5.8e-07 29.5 3.4 5.8e-07 29.5 3.4 2.1 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_7 PF12838.7 KFX98886.1 - 0.0055 17.3 6.5 0.0055 17.3 6.5 2.4 2 1 0 2 2 2 1 4Fe-4S dicluster domain Fer2 PF00111.27 KFX98886.1 - 0.0092 15.9 0.4 0.0092 15.9 0.4 2.4 2 1 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Fer4_9 PF13187.6 KFX98886.1 - 0.87 9.8 12.5 1.2 9.3 9.0 2.6 2 1 0 2 2 2 0 4Fe-4S dicluster domain Fer4_18 PF13746.6 KFX98886.1 - 1.5 9.1 7.8 0.58 10.4 0.1 2.6 3 0 0 3 3 3 0 4Fe-4S dicluster domain Evr1_Alr PF04777.13 KFX98887.1 - 3.1e-27 95.0 0.1 4.3e-27 94.5 0.1 1.2 1 0 0 1 1 1 1 Erv1 / Alr family APOBEC1 PF18769.1 KFX98887.1 - 0.087 13.1 0.1 0.13 12.5 0.1 1.3 1 0 0 1 1 1 0 APOBEC1 R3H PF01424.22 KFX98888.1 - 4.7e-17 61.7 0.1 8.3e-17 60.9 0.1 1.4 1 0 0 1 1 1 1 R3H domain zf-NF-X1 PF01422.17 KFX98888.1 - 0.00076 19.5 12.7 0.00076 19.5 12.7 8.5 9 1 1 10 10 10 5 NF-X1 type zinc finger Zn_clus PF00172.18 KFX98889.1 - 2.1e-06 27.7 10.2 4e-06 26.8 10.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TPR_9 PF13371.6 KFX98889.1 - 3.1e-05 24.0 1.8 0.055 13.6 0.1 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.6 KFX98889.1 - 0.0085 16.8 1.5 0.13 13.2 0.2 3.2 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.28 KFX98889.1 - 0.02 14.7 0.9 2 8.4 0.0 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.17 KFX98889.1 - 0.021 14.9 4.1 0.85 9.9 0.0 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_19 PF14559.6 KFX98889.1 - 0.026 15.0 3.7 2.9 8.5 0.2 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat Fungal_trans_2 PF11951.8 KFX98889.1 - 0.034 13.0 0.1 0.06 12.2 0.1 1.3 1 0 0 1 1 1 0 Fungal specific transcription factor domain TPR_11 PF13414.6 KFX98889.1 - 0.043 13.5 0.3 2.3 8.0 0.0 2.6 2 0 0 2 2 2 0 TPR repeat Lipase_GDSL_2 PF13472.6 KFX98890.1 - 8.3e-25 88.2 0.0 1.4e-24 87.5 0.0 1.4 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 KFX98890.1 - 1.7e-19 70.6 0.0 2.2e-19 70.3 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Glyco_hydro_61 PF03443.14 KFX98891.1 - 4.8e-58 196.5 1.0 7.3e-58 195.9 1.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Aminotran_4 PF01063.19 KFX98891.1 - 9.5e-23 81.2 0.0 1.3e-22 80.8 0.0 1.2 1 0 0 1 1 1 1 Amino-transferase class IV CSD PF00313.22 KFX98891.1 - 0.049 13.5 0.0 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 'Cold-shock' DNA-binding domain TFIID-18kDa PF02269.16 KFX98894.1 - 7e-20 70.9 0.0 1.8e-19 69.5 0.0 1.7 1 0 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit BTB PF00651.31 KFX98894.1 - 4.6e-08 33.3 0.1 1.5e-07 31.6 0.1 1.8 1 1 0 1 1 1 1 BTB/POZ domain Bromo_TP PF07524.13 KFX98894.1 - 0.027 14.5 0.0 0.88 9.6 0.0 2.5 2 0 0 2 2 2 0 Bromodomain associated DUF1242 PF06842.12 KFX98895.1 - 2.1e-12 46.6 0.0 4e-12 45.7 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1242) DUF5315 PF17242.2 KFX98896.1 - 2.1e-24 85.1 1.7 4.6e-24 84.0 1.7 1.6 1 0 0 1 1 1 1 Disordered region of unknown function (DUF5315) BORCS6 PF10157.9 KFX98896.1 - 0.094 12.9 0.1 1.1 9.5 0.0 2.2 2 0 0 2 2 2 0 BLOC-1-related complex sub-unit 6 Ribosom_S12_S23 PF00164.25 KFX98897.1 - 1.1e-50 170.0 0.7 1.5e-50 169.6 0.7 1.1 1 0 0 1 1 1 1 Ribosomal protein S12/S23 JAB PF01398.21 KFX98899.1 - 1.8e-18 66.6 0.0 2.8e-18 66.0 0.0 1.3 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.6 KFX98899.1 - 3.7e-18 66.0 0.3 6.3e-18 65.2 0.3 1.4 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function UPF0172 PF03665.13 KFX98899.1 - 0.079 13.0 0.0 0.35 10.9 0.0 1.9 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0172) DUF3113 PF11310.8 KFX98899.1 - 0.099 12.6 0.1 0.74 9.8 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3113) UTP25 PF06862.12 KFX98900.1 - 4.5e-202 672.0 0.2 5.4e-202 671.7 0.2 1.0 1 0 0 1 1 1 1 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 DEAD PF00270.29 KFX98900.1 - 1.4e-05 25.0 0.0 0.00037 20.3 0.0 2.3 1 1 0 1 1 1 1 DEAD/DEAH box helicase Nop14 PF04147.12 KFX98900.1 - 0.75 7.9 15.5 1.5 6.9 15.5 1.4 1 0 0 1 1 1 0 Nop14-like family TPT PF03151.16 KFX98902.1 - 7.7e-19 68.1 24.2 4e-16 59.2 14.4 2.2 1 1 1 2 2 2 2 Triose-phosphate Transporter family DUF2061 PF09834.9 KFX98902.1 - 0.055 14.0 0.5 0.055 14.0 0.5 2.9 3 0 0 3 3 3 0 Predicted membrane protein (DUF2061) UAA PF08449.11 KFX98902.1 - 0.056 12.6 15.5 0.12 11.6 15.1 1.8 1 1 0 1 1 1 0 UAA transporter family PDR_CDR PF06422.12 KFX98902.1 - 0.079 12.9 0.2 0.69 9.9 0.0 2.4 2 0 0 2 2 2 0 CDR ABC transporter EamA PF00892.20 KFX98902.1 - 0.75 10.0 30.9 0.49 10.6 9.0 3.9 3 1 1 4 4 4 0 EamA-like transporter family NAD_binding_8 PF13450.6 KFX98903.1 - 3.2e-08 33.7 0.0 9.2e-08 32.2 0.0 1.8 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.24 KFX98903.1 - 4.3e-08 32.9 0.0 7.2e-08 32.1 0.0 1.3 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase Pyr_redox_3 PF13738.6 KFX98903.1 - 0.0024 17.2 0.0 0.0046 16.3 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KFX98903.1 - 0.0034 16.7 0.0 0.022 14.0 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KFX98903.1 - 0.011 15.0 0.1 0.02 14.1 0.1 1.4 1 0 0 1 1 1 0 Thi4 family FAD_oxidored PF12831.7 KFX98903.1 - 0.011 15.1 0.0 0.016 14.6 0.0 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 KFX98903.1 - 0.014 14.7 0.0 0.024 13.9 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain TrkA_N PF02254.18 KFX98903.1 - 0.045 14.0 0.0 0.11 12.8 0.0 1.6 1 0 0 1 1 1 0 TrkA-N domain DAO PF01266.24 KFX98903.1 - 0.064 12.8 0.1 0.12 11.9 0.1 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 KFX98903.1 - 0.14 11.2 0.1 0.25 10.4 0.1 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein WD40 PF00400.32 KFX98904.1 - 1.5e-28 98.4 10.3 2.2e-10 40.9 0.1 4.2 4 1 1 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFX98904.1 - 3.4e-09 36.9 0.3 0.052 13.8 0.1 3.6 1 1 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KFX98904.1 - 3.5e-05 22.9 0.0 0.2 10.6 0.0 2.9 1 1 2 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 KFX98904.1 - 0.00016 21.5 0.4 0.36 10.8 0.0 3.6 3 0 0 3 3 3 2 WD40-like Beta Propeller Repeat DUF5570 PF17731.1 KFX98904.1 - 0.029 14.5 0.7 5.7 7.1 0.0 2.9 1 1 2 3 3 3 0 Family of unknown function (DUF5570) WD40_like PF17005.5 KFX98904.1 - 0.043 13.1 0.0 0.81 9.0 0.0 2.2 1 1 1 2 2 2 0 WD40-like domain Septin PF00735.18 KFX98907.1 - 1.8e-35 122.6 0.4 4.3e-35 121.4 0.0 1.7 2 0 0 2 2 2 1 Septin Casc1_N PF15927.5 KFX98907.1 - 0.0096 15.6 7.1 0.0096 15.6 7.1 1.4 2 0 0 2 2 2 1 Cancer susceptibility candidate 1 N-terminus FOXP-CC PF16159.5 KFX98907.1 - 0.067 13.8 0.3 0.067 13.8 0.3 2.0 2 1 0 2 2 2 0 FOXP coiled-coil domain Adaptin_binding PF10199.9 KFX98907.1 - 0.83 10.3 6.3 1 10.0 6.3 1.4 1 1 0 1 1 1 0 Alpha and gamma adaptin binding protein p34 BCDHK_Adom3 PF10436.9 KFX98908.1 - 2.7e-49 167.1 0.4 5.5e-49 166.1 0.3 1.6 2 0 0 2 2 2 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.26 KFX98908.1 - 1.2e-06 29.0 0.0 3.5e-06 27.5 0.0 1.7 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 KFX98908.1 - 0.023 14.5 0.0 0.045 13.6 0.0 1.4 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF2688 PF10892.8 KFX98908.1 - 0.17 11.4 0.0 0.43 10.1 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2688) USP7_ICP0_bdg PF12436.8 KFX98909.1 - 6.2e-83 277.8 0.4 2e-81 272.8 0.1 3.0 2 1 1 3 3 3 2 ICP0-binding domain of Ubiquitin-specific protease 7 USP7_C2 PF14533.6 KFX98909.1 - 1.9e-75 253.1 4.9 7.4e-73 244.6 0.3 3.7 4 0 0 4 4 4 2 Ubiquitin-specific protease C-terminal UCH PF00443.29 KFX98909.1 - 1.2e-46 159.4 1.3 2.1e-46 158.5 1.3 1.5 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KFX98909.1 - 1.9e-20 73.7 0.4 1.9e-20 73.7 0.4 1.9 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase MATH PF00917.26 KFX98909.1 - 2.6e-09 37.2 0.5 1.3e-08 34.9 0.2 2.3 2 0 0 2 2 2 1 MATH domain YukD PF08817.10 KFX98909.1 - 0.0064 17.2 0.0 0.61 10.8 0.0 3.2 3 0 0 3 3 3 1 WXG100 protein secretion system (Wss), protein YukD ubiquitin PF00240.23 KFX98909.1 - 0.01 15.6 0.0 88 3.0 0.0 5.1 5 0 0 5 5 5 0 Ubiquitin family DUF3601 PF12208.8 KFX98909.1 - 0.089 12.9 0.2 0.31 11.2 0.2 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF3601) EMP24_GP25L PF01105.24 KFX98910.1 - 1.2e-45 155.7 3.5 1.3e-45 155.6 3.5 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD 7tm_1 PF00001.21 KFX98910.1 - 0.029 13.7 0.4 0.068 12.5 0.1 1.7 2 0 0 2 2 2 0 7 transmembrane receptor (rhodopsin family) KAP_NTPase PF07693.14 KFX98910.1 - 0.058 12.6 0.8 0.074 12.3 0.8 1.1 1 0 0 1 1 1 0 KAP family P-loop domain SKIP_SNW PF02731.15 KFX98911.1 - 1.2e-72 242.8 5.9 1.2e-72 242.8 5.9 2.3 2 0 0 2 2 2 1 SKIP/SNW domain IMUP PF15761.5 KFX98911.1 - 0.48 11.1 9.9 0.23 12.1 6.3 2.4 2 1 0 2 2 2 0 Immortalisation up-regulated protein DUF4603 PF15376.6 KFX98911.1 - 3.9 4.8 15.6 5.2 4.3 15.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4603) FAM60A PF15396.6 KFX98911.1 - 6.8 6.6 7.9 16 5.4 7.9 1.7 1 0 0 1 1 1 0 Protein Family FAM60A Tim17 PF02466.19 KFX98912.1 - 7.6e-38 129.3 6.8 7.6e-38 129.3 6.8 1.8 2 0 0 2 2 2 1 Tim17/Tim22/Tim23/Pmp24 family DUF4048 PF13257.6 KFX98913.1 - 5.9e-16 59.1 30.2 1.2e-15 58.1 5.7 4.1 2 1 1 3 3 3 2 Domain of unknown function (DUF4048) Ribosomal_L29 PF00831.23 KFX98913.1 - 0.34 10.9 4.2 0.62 10.1 4.2 1.4 1 0 0 1 1 1 0 Ribosomal L29 protein DNA_ligase_A_N PF04675.14 KFX98914.1 - 6e-17 62.5 0.0 8.5e-17 62.0 0.0 1.1 1 0 0 1 1 1 1 DNA ligase N terminus Bac_rhodopsin PF01036.18 KFX98916.1 - 6.6e-47 160.0 22.5 8.1e-47 159.6 22.5 1.0 1 0 0 1 1 1 1 Bacteriorhodopsin-like protein MerC PF03203.14 KFX98916.1 - 0.0018 18.7 5.9 0.0018 18.7 5.9 2.6 2 1 0 2 2 2 2 MerC mercury resistance protein SUR7 PF06687.12 KFX98916.1 - 0.018 14.7 6.1 0.16 11.6 0.4 2.3 2 0 0 2 2 2 0 SUR7/PalI family DUF3488 PF11992.8 KFX98916.1 - 0.85 8.5 10.1 0.24 10.3 1.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3488) CTD_bind PF04818.13 KFX98917.1 - 3.3e-14 53.4 0.5 1.1e-13 51.8 0.3 2.1 2 0 0 2 2 2 1 RNA polymerase II-binding domain. RSRP PF17069.5 KFX98917.1 - 0.00035 20.2 29.0 0.00072 19.2 29.0 1.5 1 0 0 1 1 1 1 Arginine/Serine-Rich protein 1 PRP38_assoc PF12871.7 KFX98917.1 - 1.9 9.1 39.3 0.088 13.4 32.8 2.0 2 0 0 2 2 2 0 Pre-mRNA-splicing factor 38-associated hydrophilic C-term Apt1 PF10351.9 KFX98917.1 - 4.1 6.2 11.0 0.23 10.3 5.9 1.4 2 0 0 2 2 2 0 Golgi-body localisation protein domain DUF4748 PF15932.5 KFX98918.1 - 4.7e-24 83.9 0.4 7.3e-24 83.3 0.4 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4748) Rav1p_C PF12234.8 KFX98918.1 - 0.097 11.1 0.0 0.11 10.9 0.0 1.0 1 0 0 1 1 1 0 RAVE protein 1 C terminal Exo_endo_phos PF03372.23 KFX98919.1 - 2.3e-11 43.7 0.3 5.8e-11 42.4 0.2 1.8 2 0 0 2 2 2 1 Endonuclease/Exonuclease/phosphatase family BBS2_Mid PF14783.6 KFX98919.1 - 0.12 12.4 0.1 0.53 10.4 0.0 2.0 2 0 0 2 2 2 0 Ciliary BBSome complex subunit 2, middle region CoA_transf_3 PF02515.17 KFX98920.1 - 1.5e-68 231.6 0.0 1.9e-68 231.3 0.0 1.1 1 0 0 1 1 1 1 CoA-transferase family III Tudor_2 PF18104.1 KFX98920.1 - 0.1 12.3 0.0 0.2 11.3 0.0 1.5 1 0 0 1 1 1 0 Jumonji domain-containing protein 2A Tudor domain Dynamin_M PF01031.20 KFX98921.1 - 7.3e-101 337.1 0.2 1.5e-100 336.1 0.0 1.6 2 0 0 2 2 2 1 Dynamin central region Dynamin_N PF00350.23 KFX98921.1 - 3.1e-56 190.0 0.0 5.8e-56 189.1 0.0 1.5 1 0 0 1 1 1 1 Dynamin family GED PF02212.18 KFX98921.1 - 1.5e-30 105.2 6.1 3.2e-30 104.1 6.1 1.6 1 0 0 1 1 1 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.23 KFX98921.1 - 6.1e-05 23.1 0.4 0.00043 20.3 0.4 2.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_15 PF13175.6 KFX98921.1 - 0.014 15.1 0.6 2.2 7.9 0.0 2.4 2 0 0 2 2 2 0 AAA ATPase domain PfkB PF00294.24 KFX98922.1 - 1.5e-51 175.5 1.5 1.8e-51 175.3 1.5 1.1 1 0 0 1 1 1 1 pfkB family carbohydrate kinase WD40 PF00400.32 KFX98923.1 - 5.4e-28 96.7 11.8 2.2e-05 25.1 0.3 7.5 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFX98923.1 - 6.2e-16 58.5 0.2 0.14 12.5 0.0 5.9 1 1 5 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KFX98923.1 - 7.9e-05 22.6 0.2 0.34 10.8 0.0 3.4 2 2 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A CLTH PF10607.9 KFX98923.1 - 0.0031 17.4 0.1 0.0072 16.2 0.1 1.6 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain WD40_3 PF15911.5 KFX98923.1 - 0.008 16.2 0.0 0.78 9.8 0.0 2.6 2 0 0 2 2 2 1 WD domain, G-beta repeat PD40 PF07676.12 KFX98923.1 - 0.0092 15.9 0.3 77 3.4 0.0 4.7 5 0 0 5 5 5 0 WD40-like Beta Propeller Repeat Nup160 PF11715.8 KFX98923.1 - 0.026 13.2 0.1 0.27 9.8 0.1 2.3 2 0 0 2 2 2 0 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 KFX98923.1 - 0.14 11.1 0.2 2.1 7.2 0.1 2.4 2 1 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein ATP-synt_ab PF00006.25 KFX98924.1 - 4.7e-109 363.0 0.0 7.1e-109 362.4 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_Xtn PF16886.5 KFX98924.1 - 1.9e-46 156.8 0.0 4e-46 155.8 0.0 1.6 1 0 0 1 1 1 1 ATPsynthase alpha/beta subunit N-term extension ATP-synt_ab_N PF02874.23 KFX98924.1 - 3.6e-15 56.2 4.9 7.4e-15 55.2 4.9 1.6 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain DUF2722 PF10846.8 KFX98924.1 - 0.067 12.1 1.1 0.098 11.6 1.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) NMT1 PF09084.11 KFX98925.1 - 3e-06 27.3 0.0 8.6e-06 25.9 0.0 1.7 1 1 1 2 2 2 2 NMT1/THI5 like NMT1_3 PF16868.5 KFX98925.1 - 0.074 12.5 0.0 0.11 11.9 0.0 1.2 1 0 0 1 1 1 0 NMT1-like family UQ_con PF00179.26 KFX98926.1 - 2.4e-50 169.8 0.0 2.7e-50 169.7 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 KFX98926.1 - 0.044 13.5 0.0 0.12 12.1 0.0 1.7 1 1 0 1 1 1 0 Prokaryotic E2 family B Sec63 PF02889.16 KFX98938.1 - 4.2e-131 435.7 0.0 6.4e-77 258.2 0.0 2.2 2 0 0 2 2 2 2 Sec63 Brl domain DEAD PF00270.29 KFX98938.1 - 3.2e-50 170.3 0.2 9.6e-26 90.6 0.3 2.9 3 0 0 3 3 3 2 DEAD/DEAH box helicase ResIII PF04851.15 KFX98938.1 - 1.2e-20 74.2 0.0 2.1e-09 37.6 0.0 2.4 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit Helicase_C PF00271.31 KFX98938.1 - 5.4e-16 58.9 0.1 8.7e-07 29.3 0.0 4.3 4 2 0 4 4 3 2 Helicase conserved C-terminal domain AAA_30 PF13604.6 KFX98938.1 - 1.2e-07 31.7 0.1 0.011 15.5 0.5 2.6 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.6 KFX98938.1 - 1.4e-07 31.8 0.8 0.011 16.0 0.0 4.0 3 2 0 3 3 3 2 AAA domain AAA_19 PF13245.6 KFX98938.1 - 1.3e-05 25.6 0.4 0.0049 17.2 0.6 2.9 2 0 0 2 2 2 1 AAA domain AAA PF00004.29 KFX98938.1 - 0.00018 21.9 0.1 1.6 9.1 0.0 4.5 3 1 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) IstB_IS21 PF01695.17 KFX98938.1 - 0.018 14.7 0.1 6.4 6.5 0.0 3.2 3 0 0 3 3 3 0 IstB-like ATP binding protein T2SSE PF00437.20 KFX98938.1 - 0.055 12.5 0.0 2.9 6.9 0.0 2.5 2 0 0 2 2 2 0 Type II/IV secretion system protein TniB PF05621.11 KFX98938.1 - 0.083 12.3 0.4 17 4.8 0.1 3.6 4 0 0 4 4 4 0 Bacterial TniB protein PhoH PF02562.16 KFX98938.1 - 0.12 11.8 0.0 5.2 6.5 0.0 2.5 2 0 0 2 2 2 0 PhoH-like protein FSH1 PF03959.13 KFX98940.1 - 1.6e-30 106.4 0.0 3.8e-30 105.2 0.0 1.6 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_6 PF12697.7 KFX98940.1 - 0.047 14.3 0.0 0.053 14.1 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family Reprolysin_5 PF13688.6 KFX98941.1 - 0.023 14.9 0.0 0.037 14.2 0.0 1.4 1 0 0 1 1 1 0 Metallo-peptidase family M12 Cyclin_N PF00134.23 KFX98942.1 - 2.7e-05 23.9 0.2 0.0064 16.2 0.1 2.5 2 1 0 2 2 2 2 Cyclin, N-terminal domain TFIIB PF00382.19 KFX98942.1 - 0.00012 22.1 0.0 0.14 12.2 0.0 2.5 2 0 0 2 2 2 2 Transcription factor TFIIB repeat ETF PF01012.21 KFX98943.1 - 3.3e-43 147.7 0.1 3.9e-43 147.4 0.1 1.1 1 0 0 1 1 1 1 Electron transfer flavoprotein domain Trp_ring PF18669.1 KFX98943.1 - 0.047 13.9 0.6 0.12 12.5 0.6 1.6 1 0 0 1 1 1 0 Trimeric autotransporter adhesin Trp ring domain Glyco_hydro_76 PF03663.14 KFX98946.1 - 3.2e-146 487.5 16.4 1.6e-115 386.5 17.5 2.1 2 0 0 2 2 2 2 Glycosyl hydrolase family 76 Glyco_hydro_88 PF07470.13 KFX98946.1 - 0.016 14.3 10.9 0.029 13.4 0.5 2.8 2 1 1 3 3 3 0 Glycosyl Hydrolase Family 88 Rax2 PF12768.7 KFX98946.1 - 0.022 14.2 0.0 0.039 13.4 0.0 1.3 1 0 0 1 1 1 0 Cortical protein marker for cell polarity Phage_holin_3_6 PF07332.11 KFX98946.1 - 1.3 9.1 4.6 18 5.4 1.6 2.5 2 0 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III NUDE_C PF04880.13 KFX98946.1 - 5.2 7.5 8.2 10 6.5 8.2 1.4 1 0 0 1 1 1 0 NUDE protein, C-terminal conserved region Pyr_redox_2 PF07992.14 KFX98947.1 - 7e-19 68.1 0.1 3.7e-18 65.8 0.1 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KFX98947.1 - 2.8e-05 23.4 0.8 0.00068 18.8 0.1 2.4 2 0 0 2 2 2 1 FAD binding domain NAD_binding_9 PF13454.6 KFX98947.1 - 4e-05 23.7 1.7 0.22 11.5 0.1 2.8 3 0 0 3 3 3 2 FAD-NAD(P)-binding Pyr_redox_3 PF13738.6 KFX98947.1 - 4.8e-05 22.8 0.5 0.027 13.7 0.2 2.5 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KFX98947.1 - 0.00027 19.8 0.2 0.021 13.5 0.1 2.2 2 0 0 2 2 2 1 HI0933-like protein FAD_binding_3 PF01494.19 KFX98947.1 - 0.0017 17.7 1.0 0.0027 17.0 0.7 1.5 1 1 0 1 1 1 1 FAD binding domain Thi4 PF01946.17 KFX98947.1 - 0.0027 17.0 0.0 0.0053 16.0 0.0 1.4 1 0 0 1 1 1 1 Thi4 family DAO PF01266.24 KFX98947.1 - 0.0027 17.3 1.7 0.0081 15.8 0.4 2.0 1 1 1 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KFX98947.1 - 0.003 17.7 0.0 0.0065 16.7 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 KFX98947.1 - 0.0033 16.5 0.1 0.23 10.5 0.1 2.2 2 0 0 2 2 2 1 Lycopene cyclase protein GIDA PF01134.22 KFX98947.1 - 0.015 14.4 4.6 0.14 11.2 0.9 2.6 2 1 1 3 3 3 0 Glucose inhibited division protein A SOG2 PF10428.9 KFX98948.1 - 0.0062 15.8 9.7 0.0068 15.7 9.7 1.1 1 0 0 1 1 1 1 RAM signalling pathway protein SKG6 PF08693.10 KFX98948.1 - 0.0094 15.3 0.5 0.019 14.3 0.5 1.5 1 0 0 1 1 1 1 Transmembrane alpha-helix domain SPX PF03105.19 KFX98948.1 - 0.013 15.5 7.0 0.014 15.3 7.0 1.1 1 0 0 1 1 1 0 SPX domain CTV_P6 PF06706.11 KFX98948.1 - 0.033 13.9 0.8 0.066 12.9 0.8 1.4 1 0 0 1 1 1 0 Citrus tristeza virus 6-kDa protein AJAP1_PANP_C PF15298.6 KFX98948.1 - 0.038 14.2 3.9 0.06 13.6 3.9 1.3 1 0 0 1 1 1 0 AJAP1/PANP C-terminus Podoplanin PF05808.11 KFX98948.1 - 0.041 14.0 3.5 0.073 13.2 3.3 1.5 1 1 0 1 1 1 0 Podoplanin Plasmodium_Vir PF05795.11 KFX98948.1 - 0.1 12.0 0.6 0.11 11.9 0.6 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein CD34_antigen PF06365.12 KFX98948.1 - 0.1 12.1 0.1 0.18 11.3 0.1 1.3 1 0 0 1 1 1 0 CD34/Podocalyxin family Ndc1_Nup PF09531.10 KFX98948.1 - 0.23 10.1 9.0 0.29 9.8 9.0 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup PRCC PF10253.9 KFX98948.1 - 0.31 11.8 9.2 0.42 11.4 9.2 1.2 1 0 0 1 1 1 0 Mitotic checkpoint regulator, MAD2B-interacting Apt1 PF10351.9 KFX98948.1 - 1.5 7.6 4.0 1.6 7.5 4.0 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain GCOM2 PF15328.6 KFX98948.1 - 1.6 9.0 6.8 2.3 8.6 6.8 1.1 1 0 0 1 1 1 0 Putative GRINL1B complex locus protein 2 DUF2650 PF10853.8 KFX98948.1 - 4.3 7.1 8.0 8.5 6.2 8.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2650) Podoplanin PF05808.11 KFX98949.1 - 0.0077 16.4 4.0 0.013 15.6 4.0 1.4 1 0 0 1 1 1 1 Podoplanin TMEM154 PF15102.6 KFX98949.1 - 0.033 14.1 0.0 0.063 13.2 0.0 1.4 1 0 0 1 1 1 0 TMEM154 protein family Adeno_E3_CR2 PF02439.15 KFX98949.1 - 0.055 13.2 0.3 0.099 12.4 0.3 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 DUF515 PF04415.12 KFX98949.1 - 3.7 5.8 11.0 4.9 5.4 11.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF515) MFS_1 PF07690.16 KFX98950.1 - 2.8e-22 79.1 41.1 2.8e-22 79.1 41.1 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily Methyltransf_2 PF00891.18 KFX98951.1 - 5.6e-12 45.4 0.0 8.9e-12 44.8 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase domain Cellulase PF00150.18 KFX98952.1 - 2.8e-14 53.2 5.8 4.1e-14 52.7 5.8 1.2 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) DUF2183 PF09949.9 KFX98954.1 - 3.9e-34 116.9 0.0 8.9e-34 115.8 0.0 1.6 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2183) Piwi PF02171.17 KFX98955.1 - 2.3e-73 247.1 1.3 3.8e-73 246.4 1.3 1.3 1 0 0 1 1 1 1 Piwi domain ArgoN PF16486.5 KFX98955.1 - 4.7e-17 62.9 0.1 4.4e-16 59.7 0.0 2.6 3 0 0 3 3 3 1 N-terminal domain of argonaute ArgoL1 PF08699.10 KFX98955.1 - 1.2e-14 53.7 0.0 2.5e-14 52.7 0.0 1.6 1 0 0 1 1 1 1 Argonaute linker 1 domain PAZ PF02170.22 KFX98955.1 - 1.6e-14 53.8 0.4 4.2e-14 52.5 0.2 1.8 2 0 0 2 2 2 1 PAZ domain ArgoL2 PF16488.5 KFX98955.1 - 2e-08 34.4 0.0 4.3e-08 33.4 0.0 1.6 1 0 0 1 1 1 1 Argonaute linker 2 domain Suf PF05843.14 KFX98956.1 - 7.5e-88 295.3 2.1 5.1e-84 282.8 0.0 3.2 3 0 0 3 3 3 2 Suppressor of forked protein (Suf) TPR_16 PF13432.6 KFX98956.1 - 0.0058 17.2 0.3 0.09 13.4 0.0 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat HAT PF02184.16 KFX98956.1 - 0.0083 16.1 0.1 0.51 10.3 0.2 2.6 2 0 0 2 2 2 1 HAT (Half-A-TPR) repeat TPR_14 PF13428.6 KFX98956.1 - 0.011 16.5 0.4 4.3 8.4 0.1 4.4 4 1 1 5 5 5 0 Tetratricopeptide repeat PP28 PF10252.9 KFX98957.1 - 2.2e-32 111.3 10.8 2.2e-32 111.3 10.8 3.1 2 1 1 3 3 3 2 Casein kinase substrate phosphoprotein PP28 Glyco_transf_92 PF01697.27 KFX98994.1 - 1.6e-10 41.1 0.1 6.3e-10 39.1 0.1 1.9 1 1 0 1 1 1 1 Glycosyltransferase family 92 Glyco_tranf_2_4 PF13704.6 KFX98994.1 - 3.1e-10 40.4 1.1 5.6e-10 39.6 1.1 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 2 Citrate_synt PF00285.21 KFX98995.1 - 1.9e-97 326.6 0.0 2.3e-97 326.3 0.0 1.1 1 0 0 1 1 1 1 Citrate synthase, C-terminal domain SIR2 PF02146.17 KFX98997.1 - 8.7e-59 198.4 0.0 1.5e-58 197.6 0.0 1.4 1 0 0 1 1 1 1 Sir2 family DUF592 PF04574.13 KFX98997.1 - 7.1e-05 22.6 0.0 0.00012 21.9 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF592) TPP_enzyme_M PF00205.22 KFX98997.1 - 0.031 14.0 0.1 0.49 10.1 0.1 2.4 2 0 0 2 2 2 0 Thiamine pyrophosphate enzyme, central domain FUSC_2 PF13515.6 KFX98998.1 - 1.7e-12 47.6 25.9 1.2e-09 38.3 8.2 2.6 2 0 0 2 2 2 2 Fusaric acid resistance protein-like ArAE_2 PF10334.9 KFX98998.1 - 7.9e-07 29.1 0.0 1.8e-06 28.0 0.0 1.5 1 0 0 1 1 1 1 Aromatic acid exporter family member 2 ArAE_2_N PF10337.9 KFX98998.1 - 3.6e-05 23.0 0.8 3.6e-05 23.0 0.8 4.0 2 1 1 3 3 3 2 Putative ER transporter, 6TM, N-terminal DUF1097 PF06496.11 KFX98998.1 - 0.0035 17.5 25.3 0.12 12.5 7.6 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF1097) FUSC PF04632.12 KFX98998.1 - 0.011 14.3 17.6 0.021 13.4 9.9 3.0 2 1 0 2 2 2 0 Fusaric acid resistance protein family 7TM-7TMR_HD PF07698.11 KFX98998.1 - 3.4 7.4 11.4 0.058 13.1 2.8 2.2 2 0 0 2 2 2 0 7TM receptor with intracellular HD hydrolase Col_cuticle_N PF01484.17 KFX98998.1 - 5.3 7.2 5.1 1.1 9.3 0.3 2.5 2 0 0 2 2 2 0 Nematode cuticle collagen N-terminal domain adh_short_C2 PF13561.6 KFX98999.1 - 2.3e-53 181.2 0.2 2.9e-53 180.9 0.2 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KFX98999.1 - 1.3e-46 158.5 0.2 1.6e-46 158.2 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KFX98999.1 - 7e-15 55.4 0.2 1.2e-14 54.7 0.2 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KFX98999.1 - 5.8e-05 22.7 0.0 0.014 14.9 0.0 2.1 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family DUF1776 PF08643.10 KFX98999.1 - 0.0004 19.8 0.0 0.00058 19.3 0.0 1.2 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) THF_DHG_CYH_C PF02882.19 KFX98999.1 - 0.00091 18.6 0.1 0.0021 17.4 0.1 1.5 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Eno-Rase_NADH_b PF12242.8 KFX98999.1 - 0.018 14.8 0.1 0.039 13.7 0.1 1.5 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase YjeF_N PF03853.15 KFX98999.1 - 0.028 14.3 0.0 4.9 7.0 0.0 2.2 2 0 0 2 2 2 0 YjeF-related protein N-terminus Shikimate_DH PF01488.20 KFX98999.1 - 0.042 13.9 0.0 0.067 13.2 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase CbtA_toxin PF06755.12 KFX99000.1 - 0.025 14.6 0.0 0.035 14.1 0.0 1.2 1 0 0 1 1 1 0 CbtA_toxin of type IV toxin-antitoxin system Malate_DH PF12434.8 KFX99000.1 - 0.76 9.9 4.4 1.7 8.7 4.4 1.6 1 0 0 1 1 1 0 Malate dehydrogenase enzyme FAD_binding_3 PF01494.19 KFX99001.1 - 5.3e-30 104.8 0.1 4.7e-18 65.6 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.14 KFX99001.1 - 6.3e-06 25.6 0.2 0.039 13.2 0.1 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase SE PF08491.10 KFX99001.1 - 1.2e-05 24.5 0.0 0.0021 17.2 0.0 2.4 2 0 0 2 2 2 2 Squalene epoxidase Pyr_redox_3 PF13738.6 KFX99001.1 - 4.6e-05 22.8 0.1 0.089 12.0 0.3 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KFX99001.1 - 0.00052 19.7 1.2 0.85 9.1 1.6 2.1 1 1 0 2 2 2 2 FAD dependent oxidoreductase Trp_halogenase PF04820.14 KFX99001.1 - 0.00053 18.9 0.0 0.13 11.1 0.0 2.8 2 1 0 3 3 3 1 Tryptophan halogenase Pyr_redox PF00070.27 KFX99001.1 - 0.002 18.7 0.1 0.78 10.3 0.0 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KFX99001.1 - 0.0028 17.8 0.2 0.0077 16.4 0.2 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 KFX99001.1 - 0.0032 16.6 0.0 1.5 7.8 0.0 2.5 3 0 0 3 3 3 2 Lycopene cyclase protein HI0933_like PF03486.14 KFX99001.1 - 0.0059 15.4 0.0 0.44 9.2 0.0 2.1 2 0 0 2 2 2 1 HI0933-like protein NAD_binding_9 PF13454.6 KFX99001.1 - 0.0097 15.9 0.3 2.1 8.3 0.1 2.3 2 0 0 2 2 2 1 FAD-NAD(P)-binding Amino_oxidase PF01593.24 KFX99001.1 - 0.012 14.9 0.0 0.025 13.9 0.0 1.5 1 0 0 1 1 1 0 Flavin containing amine oxidoreductase FAD_binding_2 PF00890.24 KFX99001.1 - 0.065 12.3 0.1 0.13 11.3 0.1 1.5 1 0 0 1 1 1 0 FAD binding domain Thi4 PF01946.17 KFX99001.1 - 0.065 12.5 0.1 0.11 11.7 0.1 1.3 1 0 0 1 1 1 0 Thi4 family DIOX_N PF14226.6 KFX99002.1 - 2.7e-15 57.1 0.0 5.1e-15 56.3 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 KFX99002.1 - 2.8e-12 47.0 0.0 4.9e-12 46.2 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily MFS_1 PF07690.16 KFX99003.1 - 2.8e-30 105.4 32.7 2.8e-30 105.4 32.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily CD225 PF04505.12 KFX99003.1 - 0.27 11.4 0.1 0.27 11.4 0.1 3.1 3 0 0 3 3 3 0 Interferon-induced transmembrane protein NADH-u_ox-rdase PF10785.9 KFX99003.1 - 0.41 11.3 4.9 1.5 9.5 1.5 3.5 2 1 1 3 3 3 0 NADH-ubiquinone oxidoreductase complex I, 21 kDa subunit Cupin_2 PF07883.11 KFX99004.1 - 1e-10 41.2 0.6 1e-10 41.2 0.6 1.6 2 0 0 2 2 2 1 Cupin domain Cupin_1 PF00190.22 KFX99004.1 - 8.3e-07 28.7 0.0 1.4e-06 28.0 0.0 1.3 1 1 0 1 1 1 1 Cupin AraC_binding PF02311.19 KFX99004.1 - 0.00098 19.0 0.1 0.0016 18.3 0.1 1.3 1 0 0 1 1 1 1 AraC-like ligand binding domain JmjC PF02373.22 KFX99004.1 - 0.0021 18.5 0.1 0.013 15.9 0.1 2.1 1 1 0 1 1 1 1 JmjC domain, hydroxylase DMSP_lyase PF16867.5 KFX99004.1 - 0.057 13.1 0.2 0.057 13.1 0.2 1.9 2 0 0 2 2 2 0 Dimethlysulfonioproprionate lyase Adhesin_P1_N PF18652.1 KFX99004.1 - 0.11 12.5 0.1 0.19 11.7 0.1 1.3 1 0 0 1 1 1 0 Adhesin P1 N-terminal domain DIOX_N PF14226.6 KFX99005.1 - 4.1e-20 72.7 0.0 8.4e-20 71.7 0.0 1.5 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 KFX99005.1 - 4e-14 52.9 0.0 7.6e-14 52.0 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily OPT PF03169.15 KFX99006.1 - 1.8e-174 581.9 45.1 2e-174 581.6 45.1 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein BofA PF07441.11 KFX99006.1 - 1.2 9.4 16.8 0.064 13.4 8.8 2.9 2 0 0 2 2 2 0 SigmaK-factor processing regulatory protein BofA DUF3099 PF11298.8 KFX99006.1 - 4.6 7.5 6.2 2.2 8.5 2.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3099) adh_short_C2 PF13561.6 KFX99010.1 - 1.1e-46 159.4 0.0 1.4e-46 159.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KFX99010.1 - 1.3e-44 152.1 0.0 1.8e-44 151.5 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KFX99010.1 - 1.4e-06 28.4 0.0 4e-06 26.9 0.0 1.7 2 0 0 2 2 2 1 KR domain TPMT PF05724.11 KFX99011.1 - 3.5e-26 92.2 0.0 5e-26 91.7 0.0 1.2 1 0 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) Methyltransf_31 PF13847.6 KFX99011.1 - 6.1e-05 22.9 0.0 0.00017 21.4 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KFX99011.1 - 0.00057 19.8 0.0 0.00082 19.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KFX99011.1 - 0.001 19.7 0.0 0.0023 18.5 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KFX99011.1 - 0.0015 19.2 0.0 0.0026 18.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KFX99011.1 - 0.0019 18.9 0.0 0.0041 17.8 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain TehB PF03848.14 KFX99011.1 - 0.093 12.1 0.0 0.14 11.6 0.0 1.2 1 0 0 1 1 1 0 Tellurite resistance protein TehB OTU PF02338.19 KFX99012.1 - 1.1e-20 74.4 0.3 2.5e-20 73.3 0.0 1.8 2 0 0 2 2 2 1 OTU-like cysteine protease Peptidase_C65 PF10275.9 KFX99012.1 - 0.0015 18.0 0.5 0.11 11.9 0.0 2.6 2 1 1 3 3 3 2 Peptidase C65 Otubain TFR_dimer PF04253.15 KFX99012.1 - 0.74 9.9 6.1 0.064 13.4 1.0 1.9 2 0 0 2 2 2 0 Transferrin receptor-like dimerisation domain AMP-binding PF00501.28 KFX99013.1 - 1.1e-71 241.6 0.0 1.5e-71 241.2 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KFX99013.1 - 2.2e-10 41.4 0.0 9.3e-10 39.4 0.0 2.2 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain Ras PF00071.22 KFX99014.1 - 5.8e-52 175.6 0.0 8.2e-52 175.1 0.0 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFX99014.1 - 4.8e-18 65.5 0.0 6.2e-17 61.9 0.0 2.1 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFX99014.1 - 0.00043 19.8 0.0 0.001 18.5 0.0 1.6 1 1 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 KFX99014.1 - 0.014 15.3 0.0 4.8 7.1 0.0 2.4 2 0 0 2 2 2 0 RsgA GTPase GTP_EFTU PF00009.27 KFX99014.1 - 0.025 14.1 0.1 5.1 6.6 0.0 2.9 2 1 1 3 3 3 0 Elongation factor Tu GTP binding domain AAA_16 PF13191.6 KFX99014.1 - 0.046 14.1 0.0 0.11 12.9 0.0 1.6 1 1 0 1 1 1 0 AAA ATPase domain FeoB_N PF02421.18 KFX99014.1 - 0.056 13.0 0.1 0.72 9.4 0.0 2.3 2 1 1 3 3 3 0 Ferrous iron transport protein B Septin PF00735.18 KFX99014.1 - 0.1 11.9 0.0 0.31 10.3 0.0 1.8 3 0 0 3 3 3 0 Septin PhoR PF11808.8 KFX99014.1 - 0.11 12.9 0.0 11 6.5 0.0 2.3 2 0 0 2 2 2 0 Phosphate regulon sensor protein PhoR AAA_25 PF13481.6 KFX99014.1 - 0.12 11.9 0.1 0.27 10.8 0.1 1.6 1 1 0 1 1 1 0 AAA domain Opy2 PF09463.10 KFX99015.1 - 1.6e-08 34.7 24.6 2.6e-08 34.0 24.6 1.3 1 0 0 1 1 1 1 Opy2 protein RHH_6 PF16762.5 KFX99015.1 - 0.049 14.3 0.5 0.099 13.3 0.5 1.5 1 0 0 1 1 1 0 Ribbon-helix-helix domain zf-CCCH_4 PF18044.1 KFX99015.1 - 0.16 11.8 0.7 0.29 11.0 0.7 1.4 1 0 0 1 1 1 0 CCCH-type zinc finger FAM76 PF16046.5 KFX99017.1 - 0.061 12.7 1.5 0.14 11.5 0.1 2.2 2 0 0 2 2 2 0 FAM76 protein zf-C2H2_3 PF13878.6 KFX99017.1 - 0.084 12.7 4.4 5.4 6.9 0.0 3.2 3 0 0 3 3 3 0 zinc-finger of acetyl-transferase ESCO Vac7 PF12751.7 KFX99018.1 - 2.5e-136 455.1 0.1 2.5e-136 455.1 0.1 2.0 2 0 0 2 2 2 1 Vacuolar segregation subunit 7 LEA_2 PF03168.13 KFX99018.1 - 0.11 13.1 0.0 4.7 7.8 0.0 2.6 2 0 0 2 2 2 0 Late embryogenesis abundant protein Ima1_N PF09779.9 KFX99023.1 - 8.8e-37 127.0 4.2 1.9e-36 125.9 4.2 1.6 1 0 0 1 1 1 1 Ima1 N-terminal domain DZR PF12773.7 KFX99023.1 - 0.18 11.9 4.2 4.1 7.5 0.2 2.4 2 0 0 2 2 2 0 Double zinc ribbon DUF1430 PF07242.11 KFX99023.1 - 0.34 11.2 0.0 0.34 11.2 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1430) zinc_ribbon_10 PF10058.9 KFX99023.1 - 3.2 7.6 6.1 4 7.2 0.7 2.7 3 0 0 3 3 3 0 Predicted integral membrane zinc-ribbon metal-binding protein HSP70 PF00012.20 KFX99025.1 - 5.8e-77 259.3 2.3 6.9e-77 259.0 2.3 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 KFX99025.1 - 2e-11 43.3 0.1 3.8e-11 42.4 0.0 1.4 2 0 0 2 2 2 1 MreB/Mbl protein KH_6 PF15985.5 KFX99026.1 - 1.6e-18 66.8 0.1 3.1e-18 65.9 0.1 1.5 1 0 0 1 1 1 1 KH domain Rrp40_N PF18311.1 KFX99026.1 - 1.8e-18 66.2 0.8 5e-18 64.8 0.6 1.9 2 0 0 2 2 2 1 Exosome complex exonuclease Rrp40 N-terminal domain DUF2190 PF09956.9 KFX99026.1 - 0.042 14.3 0.0 0.093 13.2 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2190) Lipase_3 PF01764.25 KFX99030.1 - 6.8e-06 26.0 0.0 1.3e-05 25.0 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) UPF0227 PF05728.12 KFX99030.1 - 0.06 13.3 0.0 0.099 12.6 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) Hydrolase_4 PF12146.8 KFX99030.1 - 0.064 12.5 0.0 0.11 11.7 0.0 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KFX99030.1 - 0.087 13.4 1.0 0.36 11.4 0.0 2.1 2 0 0 2 2 2 0 Alpha/beta hydrolase family Pkinase PF00069.25 KFX99037.1 - 2.1e-55 187.9 0.0 3.1e-55 187.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFX99037.1 - 1.6e-17 63.7 0.0 2.5e-17 63.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 KFX99037.1 - 1.2e-05 25.4 0.7 0.033 14.1 0.1 2.4 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kinase-like PF14531.6 KFX99037.1 - 3.2e-05 23.4 0.0 6.5e-05 22.4 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 KFX99037.1 - 0.00026 20.4 0.1 0.00054 19.4 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 KFX99037.1 - 0.041 12.8 0.0 0.084 11.8 0.0 1.4 1 1 0 1 1 1 0 Haspin like kinase domain RIO1 PF01163.22 KFX99037.1 - 0.1 12.2 0.0 0.28 10.7 0.0 1.7 1 0 0 1 1 1 0 RIO1 family RasGAP PF00616.19 KFX99041.1 - 6.8e-30 104.3 0.0 5.1e-22 78.6 0.0 3.1 2 1 1 3 3 3 2 GTPase-activator protein for Ras-like GTPase C2 PF00168.30 KFX99041.1 - 0.0056 17.0 0.0 0.017 15.4 0.0 1.9 1 1 0 1 1 1 1 C2 domain LytB_WW PF18342.1 KFX99042.1 - 0.0032 17.5 0.0 0.0069 16.5 0.0 1.5 1 0 0 1 1 1 1 Endo-beta-N-acetylglucosaminidase LytB WW domain MRP-L20 PF12824.7 KFX99043.1 - 5e-58 195.9 3.0 5.7e-58 195.7 3.0 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal protein subunit L20 Tyr_Deacylase PF02580.16 KFX99044.1 - 7.8e-51 172.4 0.2 8.8e-51 172.2 0.2 1.0 1 0 0 1 1 1 1 D-Tyr-tRNA(Tyr) deacylase Not3 PF04065.15 KFX99045.1 - 4.7e-90 301.1 24.8 8e-90 300.3 24.8 1.4 1 0 0 1 1 1 1 Not1 N-terminal domain, CCR4-Not complex component NOT2_3_5 PF04153.18 KFX99045.1 - 1.8e-38 131.6 9.8 4.7e-38 130.2 9.8 1.7 1 0 0 1 1 1 1 NOT2 / NOT3 / NOT5 family Syntaxin_2 PF14523.6 KFX99045.1 - 0.0062 16.9 3.4 0.0062 16.9 3.4 3.0 3 0 0 3 3 3 1 Syntaxin-like protein DUF2373 PF10180.9 KFX99045.1 - 0.034 14.0 1.8 0.076 12.9 1.8 1.5 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2373) Cep57_MT_bd PF06657.13 KFX99045.1 - 0.085 13.3 9.6 0.46 11.0 2.0 2.8 2 0 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 Snapin_Pallidin PF14712.6 KFX99045.1 - 1 9.8 6.6 3.7 8.0 0.3 2.7 2 0 0 2 2 2 0 Snapin/Pallidin DUF1192 PF06698.11 KFX99045.1 - 2.1 8.5 7.3 0.52 10.4 1.1 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF1192) ABC_tran_CTD PF16326.5 KFX99045.1 - 3.5 8.0 19.1 0.027 14.7 5.8 3.1 2 1 1 3 3 3 0 ABC transporter C-terminal domain Seryl_tRNA_N PF02403.22 KFX99045.1 - 3.7 7.8 19.8 0.2 11.9 6.2 2.5 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain CorA PF01544.18 KFX99045.1 - 4.6 6.5 6.0 1.1 8.5 1.2 2.1 1 1 1 2 2 2 0 CorA-like Mg2+ transporter protein Occludin_ELL PF07303.13 KFX99045.1 - 7.3 7.4 16.9 1.8 9.3 0.6 3.8 3 0 0 3 3 3 0 Occludin homology domain Aminotran_4 PF01063.19 KFX99046.1 - 9.4e-26 91.0 0.0 1.1e-24 87.6 0.0 2.0 1 1 0 1 1 1 1 Amino-transferase class IV CRM1_repeat_2 PF18784.1 KFX99046.1 - 0.053 13.2 0.2 3.5 7.3 0.0 2.2 2 0 0 2 2 2 0 CRM1 / Exportin repeat 2 FUSC_2 PF13515.6 KFX99049.1 - 5.1e-26 91.3 10.5 5.1e-26 91.3 10.5 3.3 2 1 1 3 3 3 1 Fusaric acid resistance protein-like ArAE_2 PF10334.9 KFX99049.1 - 0.0059 16.5 0.5 0.023 14.5 0.1 2.1 2 0 0 2 2 2 1 Aromatic acid exporter family member 2 FUSC-like PF12805.7 KFX99049.1 - 0.017 14.2 1.1 0.039 13.0 1.1 1.6 1 0 0 1 1 1 0 FUSC-like inner membrane protein yccS ALMT PF11744.8 KFX99049.1 - 0.42 9.4 18.7 1 8.1 0.0 3.6 4 0 0 4 4 4 0 Aluminium activated malate transporter SAYSvFN PF10260.9 KFX99049.1 - 0.57 10.1 2.5 2.4 8.1 0.8 3.0 3 0 0 3 3 3 0 Uncharacterized conserved domain (SAYSvFN) ArAE_2_N PF10337.9 KFX99049.1 - 0.59 9.1 9.3 0.016 14.2 2.0 2.0 1 1 1 2 2 2 0 Putative ER transporter, 6TM, N-terminal DNA_pol_E_B PF04042.16 KFX99050.1 - 2.1e-48 164.5 0.0 3.2e-48 163.9 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B DUF3915 PF13054.6 KFX99051.1 - 2.3 8.2 6.1 2.6 8.1 3.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3915) PRELI PF04707.14 KFX99052.1 - 3.5e-18 65.9 0.1 2.6e-16 59.8 0.0 2.3 2 1 0 2 2 2 2 PRELI-like family tRNA-synt_1b PF00579.25 KFX99053.1 - 1.8e-18 66.9 0.0 4.7e-18 65.5 0.0 1.6 1 1 0 1 1 1 1 tRNA synthetases class I (W and Y) Ras PF00071.22 KFX99057.1 - 4.7e-31 107.6 0.1 6.3e-31 107.2 0.1 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFX99057.1 - 1.3e-23 83.5 0.1 2.3e-23 82.7 0.1 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFX99057.1 - 1.7e-06 27.6 0.1 2.4e-06 27.1 0.1 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 KFX99057.1 - 9.6e-05 21.8 0.1 0.00013 21.4 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region DLIC PF05783.11 KFX99057.1 - 0.0014 17.6 0.1 0.24 10.2 0.0 2.1 2 0 0 2 2 2 2 Dynein light intermediate chain (DLIC) GCV_H PF01597.19 KFX99058.1 - 2.2e-32 111.5 0.3 2.6e-32 111.3 0.3 1.1 1 0 0 1 1 1 1 Glycine cleavage H-protein Porphobil_deam PF01379.20 KFX99059.1 - 9.4e-76 253.9 0.0 1.2e-75 253.5 0.0 1.2 1 0 0 1 1 1 1 Porphobilinogen deaminase, dipyromethane cofactor binding domain Porphobil_deamC PF03900.15 KFX99059.1 - 7e-20 71.2 0.4 1.5e-19 70.2 0.4 1.6 1 0 0 1 1 1 1 Porphobilinogen deaminase, C-terminal domain Methyltransf_23 PF13489.6 KFX99060.1 - 1.3e-22 80.4 0.0 1.9e-22 79.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KFX99060.1 - 9.4e-11 42.3 0.0 2.6e-10 40.8 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KFX99060.1 - 6.1e-10 39.6 0.0 1.4e-09 38.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KFX99060.1 - 5e-07 29.6 0.0 1.6e-05 24.7 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KFX99060.1 - 4.9e-06 27.2 0.0 6.5e-05 23.6 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.17 KFX99060.1 - 0.0042 16.6 0.0 0.052 13.0 0.0 2.1 2 0 0 2 2 2 1 Putative methyltransferase FtsJ PF01728.19 KFX99060.1 - 0.023 14.8 0.0 0.06 13.4 0.0 1.6 2 0 0 2 2 2 0 FtsJ-like methyltransferase JUPITER PF17054.5 KFX99060.1 - 0.043 13.3 0.1 0.061 12.8 0.1 1.2 1 0 0 1 1 1 0 Microtubule-Associated protein Jupiter PrmA PF06325.13 KFX99060.1 - 0.067 12.6 0.0 0.1 11.9 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_2 PF00891.18 KFX99060.1 - 0.074 12.3 0.0 0.13 11.5 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase domain MTS PF05175.14 KFX99060.1 - 0.12 11.9 0.0 0.31 10.6 0.0 1.6 2 0 0 2 2 2 0 Methyltransferase small domain DUF1996 PF09362.10 KFX99061.1 - 3e-77 259.8 3.0 4.2e-77 259.3 3.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) adh_short PF00106.25 KFX99061.1 - 1.6e-22 80.0 0.0 4.5e-22 78.5 0.0 1.8 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KFX99061.1 - 4e-12 46.2 0.0 1.7e-10 40.9 0.0 2.5 2 1 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KFX99061.1 - 0.00015 21.7 0.0 0.00024 21.1 0.0 1.3 1 0 0 1 1 1 1 KR domain CBM_1 PF00734.18 KFX99061.1 - 0.0013 18.7 4.8 0.0013 18.7 4.8 3.0 4 0 0 4 4 4 1 Fungal cellulose binding domain Fungal_lectin PF07938.12 KFX99061.1 - 0.023 14.1 0.1 0.069 12.5 0.0 1.7 2 0 0 2 2 2 0 Fungal fucose-specific lectin FA_hydroxylase PF04116.13 KFX99062.1 - 8.1e-23 81.2 14.4 8.1e-23 81.2 14.4 2.3 3 0 0 3 3 3 1 Fatty acid hydroxylase superfamily Abhydrolase_3 PF07859.13 KFX99063.1 - 1.8e-24 86.8 0.0 2.4e-24 86.4 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 KFX99063.1 - 1.8e-09 36.9 0.0 2.6e-09 36.4 0.0 1.1 1 0 0 1 1 1 1 Steryl acetyl hydrolase Glyco_hydro_18 PF00704.28 KFX99076.1 - 1.2e-17 64.6 0.0 1.4e-17 64.4 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Glyco_hydro_18 PF00704.28 KFX99083.1 - 4.9e-20 72.5 0.0 5.5e-20 72.3 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 DIOX_N PF14226.6 KFX99093.1 - 9.5e-25 87.7 0.0 2.4e-24 86.4 0.0 1.7 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal WD40 PF00400.32 KFX99093.1 - 4.5e-07 30.5 6.5 0.1 13.5 0.1 6.2 6 0 0 6 6 6 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFX99093.1 - 0.0015 18.8 0.1 4.6 7.6 0.1 4.6 3 2 1 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain RNA_pol_N PF01194.17 KFX99094.1 - 1e-31 109.0 1.9 1.5e-31 108.5 0.7 1.9 2 1 0 2 2 2 1 RNA polymerases N / 8 kDa subunit Chordopox_RPO7 PF05864.12 KFX99094.1 - 0.074 13.3 0.2 0.12 12.7 0.2 1.3 1 0 0 1 1 1 0 Chordopoxvirus DNA-directed RNA polymerase 7 kDa polypeptide (RPO7) Secretin_N PF03958.17 KFX99096.1 - 0.17 12.3 3.2 9.3 6.7 0.0 3.9 3 0 0 3 3 3 0 Bacterial type II/III secretion system short domain F-box-like PF12937.7 KFX99097.1 - 0.00027 20.8 0.1 0.00053 19.8 0.1 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KFX99097.1 - 0.0073 16.2 0.0 0.014 15.3 0.0 1.4 1 0 0 1 1 1 1 F-box domain Zn_clus PF00172.18 KFX99098.1 - 1.5e-08 34.6 10.9 2.9e-08 33.7 10.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 KFX99098.1 - 1.1e-06 27.7 0.5 1.5e-06 27.3 0.5 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain TRI12 PF06609.13 KFX99100.1 - 1.5e-26 93.0 25.7 1.8e-26 92.8 25.7 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.16 KFX99100.1 - 4.6e-21 75.1 53.2 8.5e-21 74.3 49.1 3.0 2 1 0 2 2 2 1 Major Facilitator Superfamily DUF4141 PF13605.6 KFX99100.1 - 0.092 12.0 0.9 0.34 10.2 0.9 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4141) p450 PF00067.22 KFX99101.1 - 5e-55 187.1 0.0 6.2e-55 186.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF3510 PF12022.8 KFX99101.1 - 0.076 13.4 0.1 0.2 12.1 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3510) RTA1 PF04479.13 KFX99102.1 - 3e-51 174.0 9.0 3e-51 174.0 9.0 1.9 2 0 0 2 2 2 1 RTA1 like protein Fungal_trans_2 PF11951.8 KFX99103.1 - 3.5e-07 29.4 0.4 3.5e-07 29.4 0.4 1.4 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KFX99103.1 - 2e-06 27.8 10.0 4.9e-06 26.6 10.0 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TPR_12 PF13424.6 KFX99103.1 - 0.014 15.6 0.0 0.052 13.8 0.0 1.9 1 0 0 1 1 1 0 Tetratricopeptide repeat MCM PF00493.23 KFX99107.1 - 4.9e-98 326.7 0.3 7.7e-98 326.0 0.3 1.3 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 KFX99107.1 - 9.3e-30 103.1 0.0 1.6e-29 102.3 0.0 1.3 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 KFX99107.1 - 8.1e-24 83.9 0.6 1.8e-23 82.7 0.6 1.6 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 KFX99107.1 - 9.1e-12 45.5 0.3 3e-11 43.8 0.3 1.9 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 KFX99107.1 - 3.7e-07 29.8 0.0 4.8e-06 26.1 0.0 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 KFX99107.1 - 0.0017 18.2 0.0 0.0058 16.5 0.0 1.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 KFX99107.1 - 0.064 13.0 0.0 0.16 11.7 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain PfkB PF00294.24 KFX99108.1 - 4.3e-11 42.7 0.0 3.4e-05 23.3 0.1 2.1 2 0 0 2 2 2 2 pfkB family carbohydrate kinase CAP_N PF01213.19 KFX99109.1 - 5.9e-114 380.8 9.2 5.9e-114 380.8 9.2 1.6 2 1 0 2 2 2 1 Adenylate cyclase associated (CAP) N terminal CAP_C PF08603.11 KFX99109.1 - 1.8e-59 199.8 0.8 2.7e-59 199.3 0.8 1.2 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) C terminal Ribonuclease_3 PF00636.26 KFX99111.1 - 9.6e-08 32.6 0.0 4.2e-07 30.5 0.0 2.1 2 1 0 2 2 2 1 Ribonuclease III domain Ribonucleas_3_3 PF14622.6 KFX99111.1 - 3.4e-07 30.5 0.0 0.00071 19.7 0.1 2.3 2 0 0 2 2 2 2 Ribonuclease-III-like dsrm PF00035.26 KFX99111.1 - 6.9e-05 23.5 0.1 0.00024 21.7 0.0 1.9 2 0 0 2 2 2 1 Double-stranded RNA binding motif La PF05383.17 KFX99112.1 - 8.4e-17 61.0 0.0 1.3e-16 60.4 0.0 1.3 1 0 0 1 1 1 1 La domain RRM_1 PF00076.22 KFX99112.1 - 1e-08 34.9 0.2 2.3e-08 33.7 0.2 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) S4 PF01479.25 KFX99114.1 - 1.3e-16 60.0 0.0 2.2e-16 59.3 0.0 1.4 1 0 0 1 1 1 1 S4 domain DUF4763 PF15960.5 KFX99114.1 - 0.0013 18.1 1.0 0.0021 17.4 1.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4763) DUF1631 PF07793.11 KFX99114.1 - 0.035 12.6 11.5 0.043 12.3 11.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1631) S4_2 PF13275.6 KFX99114.1 - 0.06 13.2 0.0 0.12 12.2 0.0 1.4 1 0 0 1 1 1 0 S4 domain FancD2 PF14631.6 KFX99114.1 - 0.34 8.2 2.1 0.47 7.8 2.1 1.1 1 0 0 1 1 1 0 Fanconi anaemia protein FancD2 nuclease XRN_M PF17846.1 KFX99114.1 - 0.62 9.0 2.2 0.8 8.6 1.7 1.3 1 1 0 1 1 1 0 Xrn1 helical domain INCENP_ARK-bind PF03941.15 KFX99115.1 - 1.1e-17 63.7 0.6 3.7e-17 62.0 0.0 2.3 3 0 0 3 3 3 1 Inner centromere protein, ARK binding region HC2 PF07382.11 KFX99115.1 - 0.0015 18.7 22.7 0.0015 18.7 22.7 3.2 3 0 0 3 3 3 1 Histone H1-like nucleoprotein HC2 Phosphoesterase PF04185.14 KFX99116.1 - 5.3e-62 210.1 2.9 8.7e-62 209.4 2.9 1.3 1 1 0 1 1 1 1 Phosphoesterase family MFS_1 PF07690.16 KFX99117.1 - 8.8e-31 107.1 54.7 3.2e-30 105.2 54.7 1.9 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KFX99117.1 - 7.7e-08 31.6 14.2 7.7e-08 31.6 14.2 2.3 3 0 0 3 3 3 1 Sugar (and other) transporter OATP PF03137.20 KFX99117.1 - 1.1 7.5 8.3 0.2 9.9 1.7 2.5 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family Glyco_hydro_3_C PF01915.22 KFX99127.1 - 1.4e-50 172.1 0.1 2.1e-50 171.5 0.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 KFX99127.1 - 1.2e-42 146.4 0.0 2e-42 145.7 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 KFX99127.1 - 2.2e-12 46.9 0.0 4.4e-12 45.9 0.0 1.6 1 0 0 1 1 1 1 Fibronectin type III-like domain TauD PF02668.16 KFX99128.1 - 4.3e-38 131.6 0.0 6.1e-38 131.2 0.0 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DUF971 PF06155.12 KFX99128.1 - 8.9e-13 48.7 0.1 1.9e-12 47.6 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF971) GCS2 PF04107.13 KFX99128.1 - 0.11 11.8 0.4 0.21 10.9 0.4 1.3 1 0 0 1 1 1 0 Glutamate-cysteine ligase family 2(GCS2) Lactamase_B PF00753.27 KFX99130.1 - 7.9e-16 58.6 0.0 3.1e-15 56.7 0.0 2.0 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 KFX99130.1 - 0.00081 19.0 0.0 0.0015 18.1 0.0 1.5 1 1 0 1 1 1 1 Beta-lactamase superfamily domain PABP PF00658.18 KFX99131.1 - 1.1e-24 86.4 2.9 2.9e-18 65.8 0.3 2.7 2 0 0 2 2 2 2 Poly-adenylate binding protein, unique domain RINGv PF12906.7 KFX99131.1 - 2.7e-16 59.4 8.5 4.5e-16 58.7 8.5 1.4 1 0 0 1 1 1 1 RING-variant domain zf-RING_2 PF13639.6 KFX99131.1 - 0.0023 18.2 8.3 0.0039 17.5 8.3 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_4 PF14570.6 KFX99131.1 - 4.8 7.1 6.5 8.1 6.3 6.5 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-C3HC4_3 PF13920.6 KFX99131.1 - 4.9 7.1 5.4 9.6 6.2 5.4 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 KFX99131.1 - 7.9 6.2 5.9 16 5.2 5.9 1.4 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type DUF842 PF05811.13 KFX99132.1 - 0.00013 21.7 0.9 0.21 11.3 0.0 4.5 3 2 2 5 5 5 1 Eukaryotic protein of unknown function (DUF842) RRF PF01765.19 KFX99132.1 - 0.19 11.7 4.4 1.9 8.4 0.0 4.1 4 0 0 4 4 4 0 Ribosome recycling factor Apolipoprotein PF01442.18 KFX99132.1 - 0.39 10.6 51.1 0.027 14.3 1.5 6.8 3 2 3 7 7 7 0 Apolipoprotein A1/A4/E domain EzrA PF06160.12 KFX99132.1 - 7.8 4.5 8.3 0.84 7.7 1.5 2.5 3 0 0 3 3 3 0 Septation ring formation regulator, EzrA Defensin_like PF10868.8 KFX99133.1 - 0.0067 17.2 2.3 11 6.9 0.1 3.3 3 0 0 3 3 3 2 Cysteine-rich antifungal protein 2, defensin-like Macin PF14865.6 KFX99133.1 - 0.0084 16.6 1.3 13 6.4 0.0 3.2 3 0 0 3 3 3 2 Macin Defensin_5 PF18251.1 KFX99133.1 - 0.46 10.6 5.2 31 4.7 0.0 3.5 3 0 0 3 3 3 0 Fungal defensin Copsin rve PF00665.26 KFX99136.1 - 3.3e-15 56.3 0.0 7e-15 55.3 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 KFX99136.1 - 0.00036 20.6 0.0 0.00089 19.3 0.0 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain preSET_CXC PF18264.1 KFX99136.1 - 0.005 17.3 16.7 0.005 17.3 16.7 1.9 3 0 0 3 3 3 1 CXC domain rve_3 PF13683.6 KFX99136.1 - 0.063 13.1 0.0 0.16 11.8 0.0 1.7 1 0 0 1 1 1 0 Integrase core domain TCR PF03638.15 KFX99136.1 - 7.7 6.9 18.3 16 5.9 18.3 1.5 1 0 0 1 1 1 0 Tesmin/TSO1-like CXC domain, cysteine-rich domain WD40 PF00400.32 KFX99139.1 - 1.7e-130 421.1 56.3 1.4e-10 41.5 0.1 14.0 14 0 0 14 14 13 13 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFX99139.1 - 3.7e-52 174.6 9.8 2.7e-05 24.4 0.0 12.5 1 1 10 12 12 12 12 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KFX99139.1 - 1.1e-26 93.6 22.0 0.032 13.2 0.0 13.1 1 1 12 13 13 13 11 WD40 region of Ge1, enhancer of mRNA-decapping protein HET PF06985.11 KFX99139.1 - 2.5e-11 44.1 4.5 7.6e-09 36.1 0.1 2.6 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) WD40_like PF17005.5 KFX99139.1 - 1.5e-09 37.6 0.0 1.1 8.5 0.0 7.1 4 4 5 9 9 9 3 WD40-like domain PD40 PF07676.12 KFX99139.1 - 4.4e-09 36.1 15.7 18 5.4 0.0 10.5 13 0 0 13 13 12 0 WD40-like Beta Propeller Repeat Proteasome_A_N PF10584.9 KFX99139.1 - 4.3e-08 32.7 8.9 10 5.9 0.0 9.1 9 0 0 9 9 9 0 Proteasome subunit A N-terminal signature NACHT PF05729.12 KFX99139.1 - 3.6e-07 30.3 0.0 8.7e-07 29.0 0.0 1.6 1 0 0 1 1 1 1 NACHT domain Cytochrom_D1 PF02239.16 KFX99139.1 - 1.3e-06 27.2 12.8 0.035 12.6 0.1 5.7 1 1 4 6 6 6 3 Cytochrome D1 heme domain AAA_16 PF13191.6 KFX99139.1 - 6e-05 23.5 0.0 0.00031 21.2 0.0 2.2 1 0 0 1 1 1 1 AAA ATPase domain Nup160 PF11715.8 KFX99139.1 - 0.00042 19.1 19.0 0.25 9.9 0.1 7.4 2 2 6 10 10 10 2 Nucleoporin Nup120/160 Frtz PF11768.8 KFX99139.1 - 0.00044 18.7 0.0 12 4.0 0.0 5.1 2 2 5 8 8 8 0 WD repeat-containing and planar cell polarity effector protein Fritz AAA_18 PF13238.6 KFX99139.1 - 0.0026 18.3 0.0 0.017 15.7 0.0 2.5 2 1 0 2 2 2 1 AAA domain AAA_22 PF13401.6 KFX99139.1 - 0.015 15.5 0.0 0.035 14.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain DUF5122 PF17164.4 KFX99139.1 - 0.016 15.5 19.2 20 5.6 0.1 8.9 9 0 0 9 9 9 0 Domain of unknown function (DUF5122) beta-propeller DUF1258 PF06869.12 KFX99139.1 - 0.042 13.3 0.4 20 4.5 0.0 4.4 3 2 2 5 5 5 0 Protein of unknown function (DUF1258) Glyoxal_oxid_N PF07250.11 KFX99139.1 - 0.043 13.0 6.1 6.4 5.9 0.1 5.1 2 1 4 6 6 6 0 Glyoxal oxidase N-terminus APS_kinase PF01583.20 KFX99139.1 - 0.086 12.7 0.0 0.18 11.7 0.0 1.5 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA_33 PF13671.6 KFX99139.1 - 0.1 12.7 0.0 0.33 11.1 0.0 1.9 1 0 0 1 1 1 0 AAA domain Sugar_tr PF00083.24 KFX99141.1 - 1.2e-85 288.1 15.9 1.4e-85 287.9 15.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KFX99141.1 - 5.5e-29 101.2 23.1 8.8e-22 77.5 4.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 KFX99141.1 - 0.0002 20.1 17.3 0.0014 17.2 1.3 2.6 2 1 0 2 2 2 2 MFS/sugar transport protein PUCC PF03209.15 KFX99141.1 - 0.0059 15.7 2.8 0.14 11.1 0.0 2.4 2 0 0 2 2 2 2 PUCC protein Forkhead PF00250.18 KFX99157.1 - 4.7e-25 87.7 0.1 2.9e-24 85.1 0.0 2.1 2 0 0 2 2 2 1 Forkhead domain FHA PF00498.26 KFX99157.1 - 2.1e-10 40.8 0.1 7.1e-10 39.1 0.1 1.9 2 0 0 2 2 2 1 FHA domain FHA_2 PF17913.1 KFX99157.1 - 0.21 11.9 0.0 0.42 10.9 0.0 1.4 1 0 0 1 1 1 0 FHA domain Beta-lactamase PF00144.24 KFX99157.1 - 3.2 6.9 7.8 2 7.5 0.1 2.6 3 0 0 3 3 3 0 Beta-lactamase DUF4110 PF13422.6 KFX99158.1 - 0.048 13.7 1.7 0.1 12.7 1.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4110) TOH_N PF12549.8 KFX99158.1 - 0.81 9.6 6.1 2.2 8.2 0.1 3.5 3 1 0 3 3 3 0 Tyrosine hydroxylase N terminal BAG PF02179.16 KFX99159.1 - 4.5e-20 71.9 0.0 8.6e-20 71.0 0.0 1.5 1 0 0 1 1 1 1 BAG domain ubiquitin PF00240.23 KFX99159.1 - 0.00037 20.2 0.0 0.00068 19.3 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family DUF2407 PF10302.9 KFX99159.1 - 0.014 15.9 0.1 0.034 14.7 0.1 1.6 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain Rad60-SLD PF11976.8 KFX99159.1 - 0.12 12.2 0.0 0.27 11.1 0.0 1.6 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like AP3D1 PF06375.11 KFX99159.1 - 0.83 9.9 7.6 1.8 8.8 7.6 1.5 1 0 0 1 1 1 0 AP-3 complex subunit delta-1 Acetyltransf_1 PF00583.25 KFX99160.1 - 5.4e-09 36.3 0.0 7.4e-09 35.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.10 KFX99160.1 - 9.2e-06 25.5 0.0 1.5e-05 24.9 0.0 1.2 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.7 KFX99160.1 - 3.8e-05 23.6 0.0 5.5e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KFX99160.1 - 0.0017 18.7 0.0 0.0025 18.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain LCAT PF02450.15 KFX99161.1 - 0.0092 15.2 0.0 0.014 14.5 0.0 1.2 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase Abhydrolase_6 PF12697.7 KFX99161.1 - 0.02 15.5 0.0 0.047 14.3 0.0 1.7 1 0 0 1 1 1 0 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KFX99161.1 - 0.027 13.7 0.0 0.046 13.0 0.0 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 DUF676 PF05057.14 KFX99161.1 - 0.19 11.2 0.1 0.36 10.3 0.1 1.4 1 0 0 1 1 1 0 Putative serine esterase (DUF676) T5orf172 PF10544.9 KFX99166.1 - 4.7e-20 72.1 0.1 1e-19 71.0 0.1 1.6 1 0 0 1 1 1 1 T5orf172 domain MUG113 PF13455.6 KFX99166.1 - 8e-11 42.5 0.1 1.5e-10 41.6 0.1 1.5 1 0 0 1 1 1 1 Meiotically up-regulated gene 113 Menin PF05053.13 KFX99166.1 - 0.76 8.1 5.7 0.95 7.7 5.7 1.1 1 0 0 1 1 1 0 Menin DUF572 PF04502.13 KFX99166.1 - 2.6 7.6 10.6 3.4 7.2 10.6 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) PAPA-1 PF04795.12 KFX99166.1 - 4.5 8.1 10.1 3.4 8.5 6.5 2.3 2 0 0 2 2 2 0 PAPA-1-like conserved region Peptidase_S64 PF08192.11 KFX99166.1 - 9.1 4.6 6.1 11 4.4 6.1 1.1 1 0 0 1 1 1 0 Peptidase family S64 Glyco_hydro_15 PF00723.21 KFX99167.1 - 7e-47 160.2 0.0 5.3e-44 150.7 0.0 2.9 1 1 0 1 1 1 1 Glycosyl hydrolases family 15 Pkinase PF00069.25 KFX99169.1 - 3.1e-22 79.2 0.0 5.9e-14 52.1 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain TPT PF03151.16 KFX99169.1 - 2.5e-19 69.7 6.8 4.3e-19 69.0 6.8 1.3 1 1 0 1 1 1 1 Triose-phosphate Transporter family Pkinase_Tyr PF07714.17 KFX99169.1 - 8.4e-05 22.0 0.0 0.005 16.2 0.0 2.2 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KFX99169.1 - 0.068 11.9 0.2 0.17 10.7 0.0 1.7 2 0 0 2 2 2 0 Fungal protein kinase Vac7 PF12751.7 KFX99169.1 - 0.098 12.1 2.0 0.16 11.4 2.0 1.2 1 0 0 1 1 1 0 Vacuolar segregation subunit 7 EamA PF00892.20 KFX99169.1 - 0.33 11.1 34.7 0.16 12.2 11.2 2.7 2 1 0 2 2 2 0 EamA-like transporter family p450 PF00067.22 KFX99170.1 - 3.7e-51 174.3 0.0 5e-51 173.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Pkinase PF00069.25 KFX99170.1 - 4.9e-19 68.7 0.0 1.4e-18 67.2 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFX99170.1 - 3.1e-05 23.4 0.1 0.00055 19.3 0.1 2.2 1 1 0 1 1 1 1 Protein tyrosine kinase Fructosamin_kin PF03881.14 KFX99171.1 - 1.5e-31 109.7 0.0 2.1e-31 109.2 0.0 1.1 1 0 0 1 1 1 1 Fructosamine kinase APH PF01636.23 KFX99171.1 - 0.002 18.1 0.0 0.0029 17.6 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family MFS_1 PF07690.16 KFX99172.1 - 8.1e-35 120.4 37.8 1.8e-34 119.2 29.1 2.3 1 1 1 2 2 2 1 Major Facilitator Superfamily NACHT PF05729.12 KFX99172.1 - 2.7e-06 27.4 0.1 5.5e-06 26.4 0.1 1.5 1 0 0 1 1 1 1 NACHT domain ANAPC4_WD40 PF12894.7 KFX99172.1 - 2.5e-05 24.5 0.0 0.16 12.3 0.0 4.3 4 1 1 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain DUF676 PF05057.14 KFX99172.1 - 0.00025 20.6 0.0 0.00053 19.6 0.0 1.5 1 0 0 1 1 1 1 Putative serine esterase (DUF676) PGAP1 PF07819.13 KFX99172.1 - 0.00028 20.7 0.1 0.0012 18.6 0.0 2.1 2 1 0 2 2 2 1 PGAP1-like protein AAA_16 PF13191.6 KFX99172.1 - 0.0062 16.9 0.0 0.016 15.6 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain Abhydrolase_6 PF12697.7 KFX99172.1 - 0.01 16.5 0.0 0.036 14.7 0.0 2.0 2 0 0 2 2 2 0 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KFX99172.1 - 0.1 11.9 0.0 0.21 10.8 0.0 1.4 1 0 0 1 1 1 0 Serine aminopeptidase, S33 DUF5325 PF17259.2 KFX99172.1 - 0.15 12.0 0.6 0.83 9.6 0.2 2.5 2 0 0 2 2 2 0 Family of unknown function (DUF5325) 6PGD PF00393.19 KFX99173.1 - 1e-127 425.5 0.0 1.3e-127 425.1 0.0 1.1 1 0 0 1 1 1 1 6-phosphogluconate dehydrogenase, C-terminal domain NAD_binding_2 PF03446.15 KFX99173.1 - 3.6e-50 170.2 0.0 5.3e-50 169.7 0.0 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.17 KFX99173.1 - 0.061 13.9 0.0 0.14 12.8 0.0 1.7 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent NAD_binding_11 PF14833.6 KFX99173.1 - 0.096 12.9 0.0 0.32 11.2 0.0 1.9 2 0 0 2 2 2 0 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase HPS3_Mid PF14762.6 KFX99173.1 - 0.19 10.4 0.0 0.29 9.8 0.0 1.1 1 0 0 1 1 1 0 Hermansky-Pudlak syndrome 3, middle region HIT PF01230.23 KFX99174.1 - 2.3e-14 53.9 0.1 1.4e-13 51.4 0.1 2.3 2 1 0 2 2 2 1 HIT domain DcpS_C PF11969.8 KFX99174.1 - 6e-05 23.5 0.1 0.00035 21.0 0.1 2.1 1 1 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding CwfJ_C_1 PF04677.15 KFX99174.1 - 0.0041 17.0 0.9 0.018 14.9 0.3 2.2 2 1 0 2 2 2 1 Protein similar to CwfJ C-terminus 1 Nop14 PF04147.12 KFX99176.1 - 4.5 5.4 26.8 5.3 5.1 26.8 1.0 1 0 0 1 1 1 0 Nop14-like family Mif2_N PF15624.6 KFX99176.1 - 9.9 6.9 20.9 23 5.7 0.0 3.2 1 1 2 3 3 3 0 Kinetochore CENP-C fungal homologue, Mif2, N-terminal WD40 PF00400.32 KFX99177.1 - 7.3e-45 150.1 24.6 3.1e-08 34.2 0.2 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFX99177.1 - 5.1e-09 36.3 0.4 0.063 13.6 0.0 4.5 3 1 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KFX99177.1 - 0.00014 20.7 4.5 0.03 13.0 0.1 4.1 2 1 2 5 5 5 2 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 KFX99177.1 - 0.0068 15.4 0.0 11 4.9 0.0 3.8 2 2 1 4 4 4 1 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 KFX99177.1 - 0.011 15.0 0.0 0.66 9.2 0.0 2.6 2 1 0 3 3 3 0 WD40-like domain Cytochrom_D1 PF02239.16 KFX99177.1 - 0.027 13.0 0.1 3.6 6.0 0.1 2.2 2 0 0 2 2 2 0 Cytochrome D1 heme domain PD40 PF07676.12 KFX99177.1 - 0.031 14.2 0.9 25 5.0 0.0 4.4 6 0 0 6 6 6 0 WD40-like Beta Propeller Repeat TAF8_C PF10406.9 KFX99178.1 - 2.9e-19 69.4 0.9 2.9e-19 69.4 0.9 2.6 3 0 0 3 3 3 1 Transcription factor TFIID complex subunit 8 C-term Bromo_TP PF07524.13 KFX99178.1 - 1.1e-05 25.4 0.0 1.9e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 Bromodomain associated ORC6 PF05460.13 KFX99178.1 - 0.99 8.6 7.1 1.9 7.7 7.1 1.5 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) Mitochondr_Som1 PF11093.8 KFX99179.1 - 9.6e-27 92.8 0.0 1.1e-26 92.7 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial export protein Som1 ABC1 PF03109.16 KFX99190.1 - 3.9e-20 72.2 0.0 5.3e-10 39.5 0.0 2.5 2 0 0 2 2 2 2 ABC1 family APH PF01636.23 KFX99190.1 - 0.029 14.3 0.5 0.23 11.4 0.0 2.4 2 0 0 2 2 2 0 Phosphotransferase enzyme family RIO1 PF01163.22 KFX99190.1 - 0.18 11.4 0.0 0.46 10.1 0.0 1.6 1 0 0 1 1 1 0 RIO1 family Cyto_heme_lyase PF01265.17 KFX99191.1 - 1.6e-117 392.3 1.4 1.8e-117 392.1 1.4 1.0 1 0 0 1 1 1 1 Cytochrome c/c1 heme lyase TPT PF03151.16 KFX99194.1 - 2.3e-55 188.0 7.8 2.8e-55 187.7 7.8 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 KFX99194.1 - 4.1e-09 36.7 28.8 3.1e-05 24.2 8.8 3.3 2 1 0 2 2 2 2 EamA-like transporter family UAA PF08449.11 KFX99194.1 - 4e-05 23.0 14.9 0.00061 19.1 14.9 2.2 1 1 0 1 1 1 1 UAA transporter family PSII PF00421.19 KFX99194.1 - 0.0019 16.9 0.0 0.003 16.3 0.0 1.2 1 0 0 1 1 1 1 Photosystem II protein NT-C2 PF10358.9 KFX99197.1 - 3.2e-34 117.7 0.0 3.8e-34 117.5 0.0 1.0 1 0 0 1 1 1 1 N-terminal C2 in EEIG1 and EHBP1 proteins A_deamin PF02137.18 KFX99198.1 - 1.2e-30 107.1 0.0 1.6e-30 106.7 0.0 1.1 1 0 0 1 1 1 1 Adenosine-deaminase (editase) domain zf-C6H2 PF15801.5 KFX99199.1 - 0.026 14.8 7.9 0.062 13.6 7.9 1.6 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding DUF2203 PF09969.9 KFX99199.1 - 0.075 13.8 0.1 0.075 13.8 0.1 2.7 3 1 0 3 3 3 0 Uncharacterized conserved protein (DUF2203) GIT1_C PF12205.8 KFX99199.1 - 0.25 11.4 0.1 0.25 11.4 0.1 2.5 3 0 0 3 3 3 0 G protein-coupled receptor kinase-interacting protein 1 C term SF3b10 PF07189.11 KFX99200.1 - 4.2e-39 132.5 0.0 5e-39 132.3 0.0 1.1 1 0 0 1 1 1 1 Splicing factor 3B subunit 10 (SF3b10) MAGE PF01454.19 KFX99201.1 - 2.2e-62 210.6 0.0 4.3e-62 209.6 0.0 1.5 1 0 0 1 1 1 1 MAGE family Rad21_Rec8_N PF04825.13 KFX99202.1 - 3.8e-33 113.9 0.0 8.4e-33 112.8 0.0 1.6 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein MFS_1 PF07690.16 KFX99202.1 - 9.8e-33 113.5 28.4 1.5e-32 112.9 28.4 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily Rad21_Rec8 PF04824.16 KFX99202.1 - 1e-05 24.7 0.0 2.2e-05 23.6 0.0 1.5 1 0 0 1 1 1 1 Conserved region of Rad21 / Rec8 like protein TRP PF06011.12 KFX99203.1 - 5.4e-117 391.1 21.8 7.8e-117 390.6 21.8 1.2 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.6 KFX99203.1 - 4.4e-28 98.4 0.0 6.9e-28 97.7 0.0 1.3 1 0 0 1 1 1 1 ML-like domain BTB PF00651.31 KFX99204.1 - 1.7e-29 102.3 0.1 1.1e-14 54.6 0.5 2.6 2 0 0 2 2 2 2 BTB/POZ domain Ank_5 PF13857.6 KFX99204.1 - 4.1e-06 27.0 0.0 1e-05 25.7 0.0 1.8 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 KFX99204.1 - 0.00011 22.7 0.0 0.00022 21.7 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KFX99204.1 - 0.00013 22.4 0.1 0.00053 20.5 0.0 2.1 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank PF00023.30 KFX99204.1 - 0.00026 21.3 0.2 0.0016 18.8 0.0 2.4 2 0 0 2 2 2 1 Ankyrin repeat DUF3342 PF11822.8 KFX99204.1 - 0.0017 18.5 0.1 0.0053 16.9 0.1 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF3342) Ank_3 PF13606.6 KFX99204.1 - 0.021 15.3 0.0 0.096 13.3 0.0 2.2 1 0 0 1 1 1 0 Ankyrin repeat Imm68 PF15583.6 KFX99204.1 - 0.033 14.4 3.7 0.32 11.2 3.7 2.3 1 1 0 1 1 1 0 Immunity protein 68 YqzH PF14164.6 KFX99204.1 - 2.5 8.3 4.5 64 3.7 0.0 3.0 3 0 0 3 3 3 0 YqzH-like protein Sterol-sensing PF12349.8 KFX99206.1 - 1.1e-42 145.4 7.1 2.7e-42 144.2 7.1 1.6 1 0 0 1 1 1 1 Sterol-sensing domain of SREBP cleavage-activation Patched PF02460.18 KFX99206.1 - 2.7e-12 45.6 6.0 4.2e-12 45.0 6.0 1.2 1 0 0 1 1 1 1 Patched family WD40 PF00400.32 KFX99206.1 - 0.081 13.8 3.0 0.28 12.1 0.0 3.5 4 0 0 4 4 4 0 WD domain, G-beta repeat Flavoprotein PF02441.19 KFX99206.1 - 0.097 12.4 0.4 0.3 10.8 0.4 1.9 1 0 0 1 1 1 0 Flavoprotein Sugar_tr PF00083.24 KFX99207.1 - 1.9e-86 290.7 20.6 2.2e-86 290.5 20.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KFX99207.1 - 4.5e-29 101.5 29.6 1.3e-18 67.1 14.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily VirC2 PF07181.11 KFX99208.1 - 0.058 12.9 4.3 0.11 11.9 4.2 1.5 1 1 0 1 1 1 0 VirC2 protein MFS_1 PF07690.16 KFX99210.1 - 6.7e-33 114.1 59.5 3.4e-32 111.7 58.6 2.2 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 KFX99210.1 - 1.8e-07 30.0 23.8 2.6e-07 29.5 23.8 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF3237 PF11578.8 KFX99211.1 - 7.3e-33 113.5 0.0 8.2e-33 113.3 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3237) Mob1_phocein PF03637.17 KFX99212.1 - 1.3e-41 142.4 0.0 4.8e-41 140.6 0.0 1.8 1 1 0 1 1 1 1 Mob1/phocein family Leo1 PF04004.13 KFX99213.1 - 7.6e-34 116.9 0.2 7.6e-34 116.9 0.2 1.9 2 0 0 2 2 2 1 Leo1-like protein U3_snoRNA_assoc PF08297.11 KFX99213.1 - 4.4 8.1 12.9 50 4.7 2.2 3.9 3 1 1 4 4 4 0 U3 snoRNA associated CHORD PF04968.12 KFX99214.1 - 8.8e-49 164.1 20.6 9.5e-26 90.3 9.0 2.2 2 0 0 2 2 2 2 CHORD CS PF04969.16 KFX99214.1 - 4.2e-13 50.1 0.0 6.1e-13 49.6 0.0 1.3 1 0 0 1 1 1 1 CS domain HeLo PF14479.6 KFX99215.1 - 1.3e-42 146.0 0.0 1e-41 143.1 0.0 2.0 2 0 0 2 2 2 1 Prion-inhibition and propagation Pkinase_Tyr PF07714.17 KFX99215.1 - 0.19 11.0 0.0 5 6.3 0.0 2.2 2 0 0 2 2 2 0 Protein tyrosine kinase SURF4 PF02077.15 KFX99216.1 - 7.2e-97 324.1 5.4 8.8e-97 323.9 5.4 1.1 1 0 0 1 1 1 1 SURF4 family WH2 PF02205.20 KFX99216.1 - 1.2e-10 40.8 1.8 5.1e-10 38.9 1.8 2.2 1 0 0 1 1 1 1 WH2 motif DUF1643 PF07799.12 KFX99217.1 - 0.027 14.6 0.1 0.053 13.7 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1643) NIR_SIR PF01077.22 KFX99217.1 - 0.093 12.2 0.0 0.13 11.7 0.0 1.3 1 0 0 1 1 1 0 Nitrite and sulphite reductase 4Fe-4S domain BOP1NT PF08145.12 KFX99218.1 - 2.1e-102 342.5 8.1 3e-102 342.0 8.1 1.2 1 0 0 1 1 1 1 BOP1NT (NUC169) domain WD40 PF00400.32 KFX99218.1 - 2.8e-24 84.9 2.4 5.9e-10 39.6 0.1 5.4 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFX99218.1 - 4.9e-07 30.0 0.1 0.0015 18.8 0.0 4.0 4 1 1 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain DUF3947 PF13135.6 KFX99218.1 - 0.17 12.1 0.2 0.47 10.7 0.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3947) Tannase PF07519.11 KFX99219.1 - 8.7e-95 318.4 0.2 1e-94 318.1 0.2 1.0 1 0 0 1 1 1 1 Tannase and feruloyl esterase Peptidase_S9 PF00326.21 KFX99219.1 - 2.8e-05 23.7 0.1 0.12 11.9 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 KFX99219.1 - 0.00096 18.5 0.9 0.065 12.5 0.0 2.6 3 0 0 3 3 3 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KFX99219.1 - 0.0045 16.7 0.1 0.01 15.5 0.0 1.6 2 0 0 2 2 2 1 alpha/beta hydrolase fold Esterase PF00756.20 KFX99219.1 - 0.047 13.3 0.1 0.076 12.6 0.1 1.3 1 0 0 1 1 1 0 Putative esterase Serglycin PF04360.12 KFX99220.1 - 0.21 11.5 3.0 0.16 11.9 0.4 2.0 2 0 0 2 2 2 0 Serglycin DUF3336 PF11815.8 KFX99221.1 - 6.9e-36 123.0 0.1 8.9e-35 119.4 0.0 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF3336) Patatin PF01734.22 KFX99221.1 - 9.9e-14 52.0 1.0 2.8e-13 50.5 0.1 2.0 2 0 0 2 2 2 1 Patatin-like phospholipase HpcH_HpaI PF03328.14 KFX99222.1 - 4.8e-33 114.2 0.0 6.3e-33 113.8 0.0 1.1 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family Radical_SAM PF04055.21 KFX99222.1 - 0.065 13.6 0.0 0.28 11.6 0.0 1.9 2 0 0 2 2 2 0 Radical SAM superfamily SUIM_assoc PF16619.5 KFX99223.1 - 0.13 12.3 0.5 9.5 6.4 0.2 2.3 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 Cellulase PF00150.18 KFX99224.1 - 8.3e-08 32.0 0.0 1.3e-07 31.4 0.0 1.2 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) DUF4399 PF14347.6 KFX99224.1 - 0.035 14.5 0.0 0.12 12.8 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4399) CPL PF08144.11 KFX99225.1 - 1.4e-34 119.4 13.9 1.2e-30 106.8 0.0 5.5 4 1 1 5 5 5 2 CPL (NUC119) domain CTI PF06934.11 KFX99225.1 - 0.04 12.5 0.1 0.094 11.2 0.1 1.5 1 0 0 1 1 1 0 Fatty acid cis/trans isomerase (CTI) TFIIF_alpha PF05793.12 KFX99225.1 - 0.14 10.8 34.8 0.011 14.4 22.6 2.1 2 0 0 2 2 2 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) DUF3206 PF11472.8 KFX99225.1 - 0.15 12.1 0.0 0.36 10.8 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3206) RWD PF05773.22 KFX99226.1 - 1.9e-24 86.2 0.2 3.6e-24 85.3 0.2 1.5 1 0 0 1 1 1 1 RWD domain DFRP_C PF16543.5 KFX99226.1 - 0.00012 22.5 12.4 0.00041 20.8 12.4 2.0 1 1 0 1 1 1 1 DRG Family Regulatory Proteins, Tma46 DUF488 PF04343.13 KFX99226.1 - 0.31 11.6 3.0 0.59 10.7 3.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF488 XRN_M PF17846.1 KFX99226.1 - 0.41 9.5 4.7 0.52 9.2 4.7 1.1 1 0 0 1 1 1 0 Xrn1 helical domain TPX2 PF06886.11 KFX99226.1 - 4.6 7.5 22.1 0.098 12.9 10.5 2.4 2 0 0 2 2 2 0 Targeting protein for Xklp2 (TPX2) TPR_8 PF13181.6 KFX99227.1 - 3.5e-15 54.9 0.0 8.1e-07 28.8 0.0 4.8 5 0 0 5 5 4 3 Tetratricopeptide repeat TPR_12 PF13424.6 KFX99227.1 - 4.7e-12 46.0 1.9 3.7e-06 27.1 0.2 3.3 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 KFX99227.1 - 3e-11 42.5 1.2 7.3e-05 22.6 0.0 5.2 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_19 PF14559.6 KFX99227.1 - 6.4e-11 42.6 1.8 0.032 14.7 0.3 3.7 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_14 PF13428.6 KFX99227.1 - 2.8e-10 40.1 6.9 0.036 14.9 0.0 5.1 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_16 PF13432.6 KFX99227.1 - 3.2e-10 40.5 0.6 0.00052 20.6 0.2 4.3 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_MalT PF17874.1 KFX99227.1 - 9e-09 35.1 1.5 4.8e-05 22.9 0.0 2.7 1 1 0 2 2 2 2 MalT-like TPR region TPR_7 PF13176.6 KFX99227.1 - 1.6e-08 33.9 4.2 0.001 18.9 0.0 4.5 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_1 PF00515.28 KFX99227.1 - 8e-08 31.8 0.1 0.00031 20.4 0.0 4.3 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_10 PF13374.6 KFX99227.1 - 4.9e-05 23.0 5.9 0.12 12.3 0.1 4.6 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_9 PF13371.6 KFX99227.1 - 0.00039 20.5 1.7 1.6 8.9 0.0 3.3 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_6 PF13174.6 KFX99227.1 - 0.00039 20.9 1.6 2 9.2 0.0 4.1 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_20 PF14561.6 KFX99227.1 - 0.0035 17.6 0.3 2.3 8.6 0.0 3.3 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.6 KFX99227.1 - 0.009 15.7 0.8 1.2 8.9 0.1 3.7 4 0 0 4 4 4 1 TPR repeat TPR_17 PF13431.6 KFX99227.1 - 0.016 15.5 0.0 55 4.5 0.0 3.9 4 0 0 4 4 3 0 Tetratricopeptide repeat TPR_4 PF07721.14 KFX99227.1 - 0.017 15.7 7.6 2.1 9.2 0.1 4.6 5 0 0 5 5 3 0 Tetratricopeptide repeat DUF29 PF01724.16 KFX99227.1 - 0.097 12.9 1.3 0.1 12.8 0.1 1.6 2 0 0 2 2 1 0 Domain of unknown function DUF29 zf-His_Me_endon PF05551.11 KFX99243.1 - 3.7e-12 46.6 1.2 6.7e-12 45.7 1.2 1.4 1 0 0 1 1 1 1 Zinc-binding loop region of homing endonuclease 4HBT_3 PF13622.6 KFX99244.1 - 6.5e-52 177.2 0.0 7.7e-52 177.0 0.0 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily 4HBT PF03061.22 KFX99244.1 - 0.14 12.5 0.0 0.36 11.2 0.0 1.7 1 0 0 1 1 1 0 Thioesterase superfamily CUE PF02845.16 KFX99245.1 - 2.1e-10 40.1 0.3 4.6e-10 39.0 0.3 1.6 1 0 0 1 1 1 1 CUE domain NOA36 PF06524.12 KFX99245.1 - 0.028 13.7 4.0 0.044 13.1 4.0 1.2 1 0 0 1 1 1 0 NOA36 protein Ribosomal_S10 PF00338.22 KFX99246.1 - 1e-27 96.2 0.3 1.2e-27 96.0 0.3 1.0 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e zf-CCCH_4 PF18044.1 KFX99247.1 - 3.9e-06 26.5 4.7 7.3e-06 25.7 4.7 1.4 1 0 0 1 1 1 1 CCCH-type zinc finger zf_CCCH_4 PF18345.1 KFX99247.1 - 4.5e-05 23.4 8.2 8e-05 22.6 8.2 1.4 1 0 0 1 1 1 1 Zinc finger domain zf-CCCH PF00642.24 KFX99247.1 - 0.00013 21.8 1.4 0.00024 20.9 1.4 1.5 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Torus PF16131.5 KFX99247.1 - 0.0031 18.2 0.3 0.0063 17.2 0.3 1.5 1 0 0 1 1 1 1 Torus domain Tim17 PF02466.19 KFX99258.1 - 1e-25 90.3 3.6 1.5e-25 89.7 3.6 1.2 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family DUF2428 PF10350.9 KFX99259.1 - 1.6e-57 194.9 0.3 5.4e-57 193.2 0.0 2.0 2 0 0 2 2 2 1 Putative death-receptor fusion protein (DUF2428) HEAT PF02985.22 KFX99259.1 - 0.017 15.3 0.5 12 6.5 0.0 5.1 5 0 0 5 5 5 0 HEAT repeat TEX15 PF15326.6 KFX99259.1 - 0.033 13.9 2.0 0.048 13.4 0.6 1.8 2 0 0 2 2 2 0 Testis expressed sequence 15 MOR2-PAG1_C PF14225.6 KFX99259.1 - 0.05 13.5 0.1 0.18 11.7 0.1 1.9 1 0 0 1 1 1 0 Cell morphogenesis C-terminal NEMP PF10225.9 KFX99259.1 - 0.076 12.7 0.0 0.21 11.2 0.0 1.7 1 1 0 1 1 1 0 NEMP family MMS22L_C PF14911.6 KFX99259.1 - 0.11 11.5 0.1 0.21 10.7 0.1 1.3 1 0 0 1 1 1 0 S-phase genomic integrity recombination mediator, C-terminal MAPEG PF01124.18 KFX99260.1 - 5.1e-22 78.2 1.4 6e-22 77.9 1.4 1.1 1 0 0 1 1 1 1 MAPEG family XPA_C PF05181.12 KFX99282.1 - 3e-25 87.9 2.6 3e-25 87.9 2.6 1.9 2 0 0 2 2 2 1 XPA protein C-terminus XPA_N PF01286.18 KFX99282.1 - 8.3e-05 22.5 1.1 0.00016 21.6 1.1 1.5 1 0 0 1 1 1 1 XPA protein N-terminal PQ-loop PF04193.14 KFX99288.1 - 1.9e-37 126.8 14.3 7e-21 73.8 0.0 3.4 3 1 1 4 4 4 2 PQ loop repeat ER_lumen_recept PF00810.18 KFX99288.1 - 0.19 12.6 2.7 1.5 9.6 0.2 2.5 2 1 0 2 2 2 0 ER lumen protein retaining receptor Glyco_hydro_17 PF00332.18 KFX99289.1 - 9.4e-36 124.0 2.5 4e-34 118.6 2.5 2.0 1 1 0 1 1 1 1 Glycosyl hydrolases family 17 PAM2 PF07145.15 KFX99290.1 - 0.82 9.5 20.9 1 9.2 0.0 5.1 5 1 1 6 6 6 0 Ataxin-2 C-terminal region Phosphodiest PF01663.22 KFX99291.1 - 9.9e-94 314.8 0.1 1.3e-93 314.5 0.1 1.1 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.23 KFX99291.1 - 0.0024 17.3 0.2 0.11 11.9 0.2 2.5 1 1 0 1 1 1 1 Sulfatase PglZ PF08665.12 KFX99291.1 - 0.064 13.3 0.0 0.13 12.3 0.0 1.4 1 0 0 1 1 1 0 PglZ domain DUF2063 PF09836.9 KFX99291.1 - 0.086 13.1 0.0 0.21 11.9 0.0 1.5 1 0 0 1 1 1 0 Putative DNA-binding domain Med26 PF08711.11 KFX99292.1 - 2.5e-09 37.0 0.0 5.2e-09 36.0 0.0 1.6 1 0 0 1 1 1 1 TFIIS helical bundle-like domain Nup54 PF13874.6 KFX99293.1 - 5.7e-39 133.4 0.0 5.7e-39 133.4 0.0 2.8 3 1 0 3 3 3 1 Nucleoporin complex subunit 54 Nucleoporin_FG PF13634.6 KFX99293.1 - 4.6e-14 53.0 86.3 6.7e-09 36.5 37.4 2.8 1 1 1 2 2 2 2 Nucleoporin FG repeat region Nup54_57_C PF18570.1 KFX99293.1 - 2.6e-10 39.7 0.1 5.8e-10 38.6 0.1 1.6 1 0 0 1 1 1 1 NUP57/Nup54 C-terminal domain PMSI1 PF15322.6 KFX99293.1 - 0.14 11.6 10.7 0.31 10.4 10.7 1.5 1 0 0 1 1 1 0 Protein missing in infertile sperm 1, putative Ub-RnfH PF03658.14 KFX99293.1 - 0.41 11.1 4.8 8.5 6.8 0.2 2.8 1 1 0 2 2 2 0 RnfH family Ubiquitin Peptidase_S64 PF08192.11 KFX99293.1 - 6.6 5.1 18.0 0.59 8.6 12.3 1.8 2 0 0 2 2 2 0 Peptidase family S64 NADH-u_ox-rdase PF10785.9 KFX99294.1 - 9.1e-30 103.2 0.2 1.4e-29 102.6 0.2 1.3 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase complex I, 21 kDa subunit NADH_u_ox_C PF12853.7 KFX99294.1 - 3.5e-28 97.4 0.1 5.1e-28 96.9 0.1 1.2 1 0 0 1 1 1 1 C-terminal of NADH-ubiquinone oxidoreductase 21 kDa subunit dCMP_cyt_deam_1 PF00383.23 KFX99295.1 - 3.3e-23 81.5 0.0 5.2e-23 80.8 0.0 1.3 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 KFX99295.1 - 4.6e-16 58.8 0.0 9.8e-07 28.6 0.0 2.3 2 1 0 2 2 2 2 MafB19-like deaminase Bd3614-deam PF14439.6 KFX99295.1 - 4.8e-06 26.7 0.0 7.3e-06 26.1 0.0 1.2 1 0 0 1 1 1 1 Bd3614-like deaminase adh_short PF00106.25 KFX99297.1 - 5.7e-43 146.6 0.8 6.7e-43 146.4 0.8 1.0 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KFX99297.1 - 3.6e-32 111.8 0.7 4e-32 111.6 0.7 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KFX99297.1 - 2.2e-09 37.5 0.8 3.1e-09 37.0 0.8 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 KFX99297.1 - 7e-05 22.8 1.8 0.00013 21.9 1.8 1.5 1 1 0 1 1 1 1 NAD(P)H-binding Polysacc_synt_2 PF02719.15 KFX99297.1 - 0.0015 17.7 0.3 0.0036 16.5 0.1 1.6 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein Epimerase PF01370.21 KFX99297.1 - 0.0033 16.9 0.0 0.11 11.9 0.0 2.1 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family TrkA_N PF02254.18 KFX99297.1 - 0.0063 16.8 0.1 0.081 13.2 0.0 2.2 2 0 0 2 2 2 1 TrkA-N domain DUF1776 PF08643.10 KFX99297.1 - 0.0065 15.9 0.0 0.0082 15.5 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) PP2C_2 PF13672.6 KFX99297.1 - 0.18 11.4 1.6 0.14 11.8 0.3 1.4 2 0 0 2 2 2 0 Protein phosphatase 2C CBFD_NFYB_HMF PF00808.23 KFX99298.1 - 2.8e-17 62.7 0.6 5.4e-17 61.8 0.3 1.6 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 KFX99298.1 - 2.2e-06 28.0 0.1 1.1e-05 25.8 0.0 1.9 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 DUF5333 PF17267.2 KFX99298.1 - 0.012 15.8 0.5 0.016 15.4 0.5 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5333) Bromo_TP PF07524.13 KFX99298.1 - 0.095 12.7 0.0 0.16 12.0 0.0 1.4 1 0 0 1 1 1 0 Bromodomain associated ADH_zinc_N PF00107.26 KFX99299.1 - 2.4e-15 56.7 0.2 4.3e-15 55.9 0.2 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KFX99299.1 - 3.5e-05 24.9 0.0 5.5e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase MORN PF02493.20 KFX99299.1 - 5.3 7.1 6.1 8.9 6.4 0.2 3.0 3 0 0 3 3 3 0 MORN repeat CNH PF00780.22 KFX99314.1 - 1.1e-79 267.9 0.0 1.7e-79 267.3 0.0 1.3 1 0 0 1 1 1 1 CNH domain PH_5 PF15405.6 KFX99314.1 - 1.3e-44 151.6 0.2 2.9e-44 150.4 0.0 1.7 2 0 0 2 2 2 1 Pleckstrin homology domain RhoGEF PF00621.20 KFX99314.1 - 3e-36 125.4 0.0 5e-36 124.6 0.0 1.4 1 0 0 1 1 1 1 RhoGEF domain DEP PF00610.21 KFX99314.1 - 6.4e-14 51.8 0.0 1.9e-13 50.3 0.0 1.8 2 0 0 2 2 2 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) PH_13 PF16652.5 KFX99314.1 - 0.005 16.7 0.1 0.055 13.3 0.0 2.5 2 1 0 2 2 2 1 Pleckstrin homology domain PH PF00169.29 KFX99314.1 - 0.055 14.0 0.0 3.1 8.4 0.0 2.9 2 0 0 2 2 2 0 PH domain ATP-synt_C PF00137.21 KFX99315.1 - 7.5e-29 99.9 34.5 1.3e-17 63.9 13.6 2.1 2 0 0 2 2 2 2 ATP synthase subunit C PI3Ka PF00613.20 KFX99316.1 - 4.3e-58 195.8 0.3 7e-58 195.1 0.3 1.3 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PI3_PI4_kinase PF00454.27 KFX99316.1 - 4.5e-43 147.9 0.0 7.5e-28 98.0 0.0 2.5 1 1 1 2 2 2 2 Phosphatidylinositol 3- and 4-kinase PI3K_C2 PF00792.24 KFX99316.1 - 1e-32 113.0 0.0 1.9e-32 112.1 0.0 1.5 1 0 0 1 1 1 1 Phosphoinositide 3-kinase C2 Nse4_C PF08743.10 KFX99317.1 - 4.6e-34 116.5 0.0 9.3e-34 115.6 0.0 1.5 1 0 0 1 1 1 1 Nse4 C-terminal Nse4-Nse3_bdg PF15412.6 KFX99317.1 - 2.9e-11 43.3 1.1 1.2e-10 41.4 0.5 2.3 2 0 0 2 2 2 1 Binding domain of Nse4/EID3 to Nse3-MAGE Sugar_tr PF00083.24 KFX99318.1 - 1.2e-120 403.4 23.1 1.4e-120 403.2 23.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KFX99318.1 - 4.2e-20 72.0 28.6 4.2e-20 72.0 28.6 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily DUF16 PF01519.16 KFX99319.1 - 0.018 15.5 1.1 1.4 9.5 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function DUF16 Nmad5 PF18757.1 KFX99319.1 - 0.027 14.7 1.5 0.051 13.8 1.5 1.4 1 0 0 1 1 1 0 Nucleotide modification associated domain 5 DUF447 PF04289.12 KFX99319.1 - 0.097 12.4 0.2 0.21 11.4 0.2 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF447) SlyX PF04102.12 KFX99319.1 - 2.7 8.7 7.8 7.7 7.2 0.9 3.1 2 1 0 2 2 2 0 SlyX DUF1749 PF08538.10 KFX99322.1 - 1.7e-96 322.8 0.0 1.9e-96 322.7 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1749) Abhydrolase_6 PF12697.7 KFX99322.1 - 5.3e-05 23.9 0.0 6.7e-05 23.6 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KFX99322.1 - 0.0028 17.0 0.0 0.0052 16.1 0.0 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 LIDHydrolase PF10230.9 KFX99322.1 - 0.032 13.8 0.1 2.1 7.9 0.1 2.2 2 0 0 2 2 2 0 Lipid-droplet associated hydrolase Ser_hydrolase PF06821.13 KFX99322.1 - 0.033 14.0 0.0 0.053 13.4 0.0 1.3 1 0 0 1 1 1 0 Serine hydrolase DUF900 PF05990.12 KFX99322.1 - 0.11 12.0 0.1 0.22 11.0 0.0 1.6 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF900) MRP-L28 PF09812.9 KFX99323.1 - 9e-08 32.4 0.1 1.3e-07 31.9 0.1 1.3 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L28 Ras PF00071.22 KFX99324.1 - 1.8e-48 164.2 0.0 3.3e-48 163.3 0.0 1.4 2 0 0 2 2 2 1 Ras family Roc PF08477.13 KFX99324.1 - 6.1e-22 78.1 0.0 1.2e-21 77.1 0.0 1.5 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFX99324.1 - 2.1e-06 27.3 0.0 3.2e-06 26.7 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 KFX99324.1 - 0.019 14.3 0.0 0.027 13.8 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region SRPRB PF09439.10 KFX99324.1 - 0.059 12.8 0.0 0.087 12.3 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit PduV-EutP PF10662.9 KFX99324.1 - 0.15 11.8 0.0 4.4 7.0 0.0 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation NST1 PF13945.6 KFX99325.1 - 5e-58 196.4 1.6 5e-58 196.4 1.6 4.6 4 1 1 5 5 5 1 Salt tolerance down-regulator Baculo_PEP_C PF04513.12 KFX99328.1 - 0.00081 19.4 12.0 1.6 8.7 0.1 4.3 2 2 2 4 4 4 2 Baculovirus polyhedron envelope protein, PEP, C terminus DUF599 PF04654.12 KFX99328.1 - 0.0045 16.4 0.3 0.0045 16.4 0.3 1.8 2 0 0 2 2 2 1 Protein of unknown function, DUF599 DUF4199 PF13858.6 KFX99328.1 - 0.047 14.1 0.3 0.047 14.1 0.3 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF4199) DUF1741 PF08427.10 KFX99329.1 - 1.3e-50 172.3 0.0 2.4e-50 171.4 0.0 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF1741) Kelch_5 PF13854.6 KFX99331.1 - 6.8e-07 29.1 0.3 2.9e-05 23.9 0.0 3.0 2 0 0 2 2 2 1 Kelch motif SKG6 PF08693.10 KFX99331.1 - 0.0026 17.1 2.4 0.0053 16.1 2.4 1.5 1 0 0 1 1 1 1 Transmembrane alpha-helix domain DUF456 PF04306.13 KFX99331.1 - 0.37 11.1 3.7 0.65 10.3 3.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF456) SPOC PF07744.13 KFX99332.1 - 1.1e-24 87.0 0.0 2.2e-24 86.1 0.0 1.5 1 0 0 1 1 1 1 SPOC domain TFIIS_M PF07500.14 KFX99332.1 - 5.2e-19 68.8 3.4 1.3e-18 67.5 3.4 1.7 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS), central domain PHD PF00628.29 KFX99332.1 - 1.2e-09 37.9 9.8 2.3e-09 37.0 9.8 1.5 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.6 KFX99332.1 - 0.6 9.7 4.8 1.2 8.8 4.8 1.5 1 0 0 1 1 1 0 PHD-finger zf-C2H2_jaz PF12171.8 KFX99333.1 - 1.4e-06 28.4 0.0 2.3e-06 27.7 0.0 1.4 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KFX99333.1 - 0.00036 20.8 0.1 0.0006 20.1 0.1 1.4 1 0 0 1 1 1 1 Zinc-finger of C2H2 type CENP-Q PF13094.6 KFX99333.1 - 0.0012 19.1 10.3 0.0012 19.1 10.3 2.0 2 0 0 2 2 2 1 CENP-Q, a CENPA-CAD centromere complex subunit AbiH PF14253.6 KFX99333.1 - 0.028 14.3 0.1 0.041 13.7 0.1 1.3 1 0 0 1 1 1 0 Bacteriophage abortive infection AbiH zf-C2H2_2 PF12756.7 KFX99333.1 - 0.056 13.8 0.0 0.11 12.8 0.0 1.4 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) DUF908 PF06012.12 KFX99333.1 - 0.25 10.7 2.6 0.46 9.8 2.6 1.4 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) Fmp27_WPPW PF10359.9 KFX99333.1 - 0.64 8.8 5.9 0.055 12.3 0.9 1.6 2 0 0 2 2 2 0 RNA pol II promoter Fmp27 protein domain FF PF01846.19 KFX99334.1 - 1.4e-10 41.2 2.4 5.6e-09 36.0 0.0 2.9 2 0 0 2 2 2 1 FF domain WW PF00397.26 KFX99334.1 - 8.8e-09 35.3 4.2 8.8e-09 35.3 4.2 1.8 2 0 0 2 2 2 1 WW domain Di19_C PF14571.6 KFX99334.1 - 0.031 14.8 0.2 0.031 14.8 0.2 3.2 3 0 0 3 3 3 0 Stress-induced protein Di19, C-terminal DUF5641 PF18701.1 KFX99334.1 - 0.072 13.3 2.8 0.08 13.1 1.3 1.9 2 0 0 2 2 2 0 Family of unknown function (DUF5641) Proteasome PF00227.26 KFX99335.1 - 1.1e-59 201.2 0.2 1.3e-59 200.9 0.2 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 KFX99335.1 - 3.2e-13 49.1 0.1 8.9e-13 47.7 0.1 1.8 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Nitrate_red_gam PF02665.14 KFX99335.1 - 0.0085 15.7 0.0 0.012 15.1 0.0 1.1 1 0 0 1 1 1 1 Nitrate reductase gamma subunit DUF5624 PF18538.1 KFX99335.1 - 0.096 12.8 0.4 0.28 11.3 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF5624) PAP2 PF01569.21 KFX99336.1 - 4.7e-24 84.7 1.1 4.7e-24 84.7 1.1 1.6 2 1 0 2 2 2 1 PAP2 superfamily RseC_MucC PF04246.12 KFX99336.1 - 1.4 8.9 5.4 0.54 10.2 0.4 2.6 3 1 1 4 4 4 0 Positive regulator of sigma(E), RseC/MucC Med7 PF05983.11 KFX99337.1 - 8.4e-68 228.2 0.1 1.2e-67 227.7 0.1 1.2 1 0 0 1 1 1 1 MED7 protein DUF2458 PF10454.9 KFX99337.1 - 0.03 14.0 0.2 0.047 13.3 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2458) DUF747 PF05346.11 KFX99338.1 - 1.4e-117 392.7 4.6 2.1e-117 392.1 4.6 1.3 1 0 0 1 1 1 1 Eukaryotic membrane protein family DNA_methylase PF00145.17 KFX99338.1 - 1.2e-46 159.6 0.0 6.3e-46 157.3 0.0 2.3 2 1 0 2 2 2 1 C-5 cytosine-specific DNA methylase BAH PF01426.18 KFX99338.1 - 2.2e-13 50.1 0.0 1.1e-09 38.2 0.0 3.4 3 0 0 3 3 3 2 BAH domain Caveolin PF01146.17 KFX99338.1 - 0.068 13.1 0.3 0.21 11.5 0.3 1.8 1 0 0 1 1 1 0 Caveolin Beta-lactamase PF00144.24 KFX99347.1 - 3.7e-21 75.7 0.0 1e-20 74.3 0.0 1.6 1 1 0 1 1 1 1 Beta-lactamase Zn_clus PF00172.18 KFX99348.1 - 1.1e-05 25.5 9.7 1.1e-05 25.5 9.7 2.0 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 KFX99348.1 - 0.00037 19.4 0.1 0.0015 17.4 0.0 1.8 2 0 0 2 2 2 1 Fungal specific transcription factor domain FAD_binding_3 PF01494.19 KFX99349.1 - 2.8e-25 89.3 0.0 3.6e-25 89.0 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.6 KFX99349.1 - 4.4e-07 29.4 0.0 7.4e-05 22.1 0.1 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KFX99349.1 - 3.9e-06 26.7 0.3 0.00021 21.0 0.2 2.2 1 1 1 2 2 2 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 KFX99349.1 - 7.2e-06 25.3 0.0 0.05 12.7 0.0 2.2 2 0 0 2 2 2 2 Lycopene cyclase protein Pyr_redox_2 PF07992.14 KFX99349.1 - 8.6e-05 21.9 0.0 0.038 13.2 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KFX99349.1 - 0.00012 22.2 0.1 0.00031 20.9 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 KFX99349.1 - 0.00019 20.3 0.0 0.0018 17.1 0.0 2.0 1 1 0 1 1 1 1 HI0933-like protein Pyr_redox PF00070.27 KFX99349.1 - 0.003 18.1 0.3 0.071 13.7 0.2 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 KFX99349.1 - 0.02 14.2 0.1 1.1 8.5 0.0 2.6 3 0 0 3 3 3 0 Flavin containing amine oxidoreductase TrkA_N PF02254.18 KFX99349.1 - 0.022 15.0 0.1 0.048 13.9 0.1 1.5 1 0 0 1 1 1 0 TrkA-N domain Trp_halogenase PF04820.14 KFX99349.1 - 0.11 11.3 0.1 0.32 9.8 0.0 1.7 2 0 0 2 2 2 0 Tryptophan halogenase MFS_1 PF07690.16 KFX99350.1 - 1.1e-32 113.4 32.0 1.4e-32 113.0 32.0 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily MASE2 PF05230.11 KFX99350.1 - 4.2 7.5 11.3 0.28 11.3 2.5 3.0 3 0 0 3 3 3 0 MASE2 domain DUF3040 PF11239.8 KFX99350.1 - 9 6.6 18.0 0.88 9.9 2.0 4.2 4 0 0 4 4 4 0 Protein of unknown function (DUF3040) Fungal_trans PF04082.18 KFX99351.1 - 2.4e-20 72.7 0.5 4.4e-20 71.8 0.5 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.26 KFX99351.1 - 1.5e-06 28.4 7.2 0.0076 16.6 2.1 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type Zn_clus PF00172.18 KFX99351.1 - 8.2e-06 25.8 6.3 8.2e-06 25.8 6.3 1.7 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-C2H2_4 PF13894.6 KFX99351.1 - 0.00014 22.4 5.7 0.21 12.5 0.1 3.4 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KFX99351.1 - 0.00062 20.1 8.7 0.00073 19.9 0.4 3.4 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_8 PF15909.5 KFX99351.1 - 0.026 14.8 0.2 0.092 13.1 0.2 2.0 1 0 0 1 1 1 0 C2H2-type zinc ribbon zf-C2H2_jaz PF12171.8 KFX99351.1 - 0.038 14.3 0.6 5.1 7.5 0.0 2.5 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-Di19 PF05605.12 KFX99351.1 - 0.2 12.0 1.4 0.51 10.7 1.4 1.7 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_6 PF13912.6 KFX99351.1 - 0.34 11.0 3.2 1.7 8.7 0.0 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger Aldo_ket_red PF00248.21 KFX99352.1 - 5.4e-48 163.7 0.1 2.4e-46 158.3 0.1 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family NUDIX PF00293.28 KFX99353.1 - 3.9e-08 33.4 0.0 9.3e-08 32.2 0.0 1.6 2 0 0 2 2 2 1 NUDIX domain DUF4743 PF15916.5 KFX99353.1 - 0.00061 19.8 0.0 0.001 19.0 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4743) MFS_1 PF07690.16 KFX99354.1 - 1.3e-28 99.9 15.0 1.9e-28 99.4 10.7 2.6 2 1 0 2 2 2 1 Major Facilitator Superfamily MFS_4 PF06779.14 KFX99354.1 - 0.0076 15.6 6.1 0.37 10.0 0.7 2.3 2 0 0 2 2 2 2 Uncharacterised MFS-type transporter YbfB DUF2970 PF11174.8 KFX99354.1 - 0.31 10.9 0.1 0.31 10.9 0.1 2.2 3 0 0 3 3 3 0 Protein of unknown function (DUF2970) O-antigen_lig PF13425.6 KFX99354.1 - 4.8 5.8 10.7 0.081 11.7 3.2 1.7 2 1 0 2 2 2 0 O-antigen ligase like membrane protein Jiraiya PF15038.6 KFX99355.1 - 0.26 10.7 4.1 0.57 9.6 4.1 1.5 1 0 0 1 1 1 0 Jiraiya Intg_mem_TP0381 PF09529.10 KFX99355.1 - 2.2 7.7 10.7 31 4.0 0.0 3.0 2 1 0 2 2 2 0 Integral membrane protein (intg_mem_TP0381) NicO PF03824.16 KFX99355.1 - 3.8 6.8 9.8 6.9 5.9 3.5 2.3 1 1 0 2 2 2 0 High-affinity nickel-transport protein FAD_binding_4 PF01565.23 KFX99356.1 - 6.6e-21 74.5 4.7 1.5e-20 73.4 4.7 1.6 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 KFX99356.1 - 0.0014 18.7 0.4 0.0026 17.8 0.4 1.5 1 0 0 1 1 1 1 Berberine and berberine like GTP_EFTU_D3 PF03143.17 KFX99357.1 - 2.7e-05 24.4 0.1 7.6e-05 23.0 0.1 1.7 1 1 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 KFX99357.1 - 0.00013 22.3 0.1 0.00067 20.0 0.0 2.1 2 0 0 2 2 2 1 Elongation factor Tu domain 2 Aldo_ket_red PF00248.21 KFX99359.1 - 1.2e-54 185.6 0.0 1.5e-54 185.3 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Dna2 PF08696.11 KFX99360.1 - 8.3e-70 234.7 0.1 2.1e-69 233.4 0.1 1.8 1 0 0 1 1 1 1 DNA replication factor Dna2 AAA_12 PF13087.6 KFX99360.1 - 8.2e-51 172.5 0.0 1.4e-50 171.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 KFX99360.1 - 1.7e-32 113.2 0.4 1.7e-16 60.8 0.0 2.5 1 1 0 2 2 2 2 AAA domain AAA_30 PF13604.6 KFX99360.1 - 1.2e-14 54.5 0.0 2.6e-14 53.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 KFX99360.1 - 5.8e-13 49.4 0.0 1.4e-12 48.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain Cas_Cas4 PF01930.17 KFX99360.1 - 1.2e-09 38.5 0.1 1.6e-08 34.9 0.1 2.4 2 0 0 2 2 2 1 Domain of unknown function DUF83 Viral_helicase1 PF01443.18 KFX99360.1 - 1.5e-07 31.4 0.6 0.33 10.6 0.0 4.1 4 1 0 4 4 4 2 Viral (Superfamily 1) RNA helicase Helicase_RecD PF05127.14 KFX99360.1 - 0.00029 20.7 0.0 0.00085 19.2 0.0 1.8 1 1 0 1 1 1 1 Helicase UvrD-helicase PF00580.21 KFX99360.1 - 0.00036 20.1 0.1 0.00082 19.0 0.1 1.6 1 0 0 1 1 1 1 UvrD/REP helicase N-terminal domain AAA_16 PF13191.6 KFX99360.1 - 0.00038 20.9 0.0 0.00099 19.5 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain PIF1 PF05970.14 KFX99360.1 - 0.00039 19.7 0.0 0.00091 18.5 0.0 1.6 1 0 0 1 1 1 1 PIF1-like helicase SRP54 PF00448.22 KFX99360.1 - 0.00069 19.3 0.1 0.0013 18.4 0.1 1.4 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain Csa1 PF06023.12 KFX99360.1 - 0.0035 16.7 0.1 0.017 14.5 0.1 1.9 1 1 0 1 1 1 1 CRISPR-associated exonuclease Csa1 CbiA PF01656.23 KFX99360.1 - 0.01 15.9 0.0 0.028 14.5 0.0 1.7 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_25 PF13481.6 KFX99360.1 - 0.011 15.3 0.0 0.31 10.6 0.0 3.0 3 0 0 3 3 3 0 AAA domain AAA_7 PF12775.7 KFX99360.1 - 0.022 14.3 0.1 0.057 12.9 0.1 1.6 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_18 PF13238.6 KFX99360.1 - 0.023 15.2 0.0 0.52 10.9 0.0 2.5 2 0 0 2 2 2 0 AAA domain cobW PF02492.19 KFX99360.1 - 0.04 13.5 0.0 0.12 11.9 0.0 1.8 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain DUF87 PF01935.17 KFX99360.1 - 0.044 13.9 1.1 0.12 12.5 0.3 2.2 2 0 0 2 2 2 0 Helicase HerA, central domain ResIII PF04851.15 KFX99360.1 - 0.054 13.5 0.0 0.15 12.1 0.0 1.7 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit DUF2075 PF09848.9 KFX99360.1 - 0.055 12.7 0.0 0.1 11.8 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) MeaB PF03308.16 KFX99360.1 - 0.061 12.3 0.0 0.2 10.6 0.0 1.8 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB UvrD_C_2 PF13538.6 KFX99360.1 - 0.069 13.0 0.0 0.19 11.6 0.0 1.8 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain NTPase_1 PF03266.15 KFX99360.1 - 0.071 13.0 0.1 0.2 11.6 0.1 1.8 1 0 0 1 1 1 0 NTPase FtsK_SpoIIIE PF01580.18 KFX99360.1 - 0.12 11.7 0.0 0.3 10.4 0.0 1.6 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_33 PF13671.6 KFX99360.1 - 0.13 12.4 0.0 0.84 9.8 0.0 2.4 3 0 0 3 3 1 0 AAA domain AAA PF00004.29 KFX99360.1 - 0.16 12.4 0.0 0.37 11.2 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF543 PF04418.12 KFX99366.1 - 9.7e-27 92.8 0.0 2.1e-26 91.7 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF543) zf-CCHC PF00098.23 KFX99366.1 - 1.7e-05 24.7 27.0 0.045 13.8 5.5 4.8 4 0 0 4 4 4 4 Zinc knuckle zf-C2H2_10 PF16588.5 KFX99366.1 - 7.5 6.4 14.5 0.27 11.0 2.3 3.1 2 1 1 3 3 3 0 C2H2 zinc-finger ORMDL PF04061.14 KFX99367.1 - 1.5e-07 31.3 0.0 2.1e-07 30.8 0.0 1.2 1 0 0 1 1 1 1 ORMDL family ORMDL PF04061.14 KFX99368.1 - 3.5e-39 133.7 0.3 3.9e-39 133.6 0.3 1.0 1 0 0 1 1 1 1 ORMDL family HsbA PF12296.8 KFX99374.1 - 5.2e-26 91.4 13.7 5.2e-26 91.4 13.7 1.5 2 0 0 2 2 2 1 Hydrophobic surface binding protein A Baculo_PEP_C PF04513.12 KFX99374.1 - 0.0031 17.6 5.4 0.091 12.8 2.8 2.1 2 0 0 2 2 2 2 Baculovirus polyhedron envelope protein, PEP, C terminus NPV_P10 PF05531.12 KFX99374.1 - 3.2 8.3 5.6 10 6.6 2.7 2.7 1 1 2 3 3 3 0 Nucleopolyhedrovirus P10 protein AAT PF03417.16 KFX99375.1 - 1.5e-18 67.4 0.0 1.1e-16 61.2 0.0 2.8 1 1 0 1 1 1 1 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase TRAPP PF04051.16 KFX99376.1 - 3.4e-35 120.9 0.1 4e-35 120.7 0.1 1.0 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component PNGaseA PF12222.8 KFX99376.1 - 0.06 12.2 0.0 0.071 11.9 0.0 1.1 1 0 0 1 1 1 0 Peptide N-acetyl-beta-D-glucosaminyl asparaginase amidase A WD40 PF00400.32 KFX99377.1 - 3.7e-40 135.2 8.4 5.9e-08 33.3 0.0 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFX99377.1 - 1.5e-12 47.6 0.3 0.0014 18.9 0.0 4.6 2 1 4 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KFX99377.1 - 0.0021 17.1 0.0 0.38 9.7 0.0 2.8 2 1 1 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 KFX99377.1 - 0.015 14.6 0.0 9.3 5.5 0.0 3.0 2 1 0 3 3 3 0 WD40-like domain Nucleoporin_N PF08801.11 KFX99377.1 - 0.083 11.6 0.1 1.5 7.5 0.0 2.3 1 1 0 2 2 2 0 Nup133 N terminal like FHA PF00498.26 KFX99387.1 - 0.00077 19.8 0.0 0.0013 19.0 0.0 1.4 1 0 0 1 1 1 1 FHA domain MFS_1 PF07690.16 KFX99388.1 - 3.8e-34 118.2 36.5 3.8e-34 118.2 36.5 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KFX99388.1 - 1.6e-05 24.0 11.8 1.6e-05 24.0 11.8 2.6 2 1 0 3 3 3 1 Sugar (and other) transporter BT1 PF03092.16 KFX99388.1 - 0.034 12.4 8.2 0.068 11.4 1.6 2.8 2 1 1 3 3 3 0 BT1 family Sugar_tr PF00083.24 KFX99389.1 - 5.2e-73 246.4 25.6 7.3e-73 245.9 25.6 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KFX99389.1 - 1.4e-14 53.8 28.0 1.4e-14 53.8 28.0 2.4 2 1 1 3 3 3 2 Major Facilitator Superfamily Glyco_hydro_32N PF00251.20 KFX99390.1 - 1.6e-49 169.2 0.0 3.5e-49 168.0 0.0 1.5 2 0 0 2 2 2 1 Glycosyl hydrolases family 32 N-terminal domain Glyco_hydro_32C PF08244.12 KFX99390.1 - 1.3e-22 80.5 0.1 2.1e-22 79.8 0.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 C terminal BNR_2 PF13088.6 KFX99390.1 - 0.025 13.9 0.1 0.07 12.4 0.1 1.6 1 1 0 1 1 1 0 BNR repeat-like domain BNR PF02012.20 KFX99390.1 - 0.088 12.9 2.5 1 9.6 0.4 3.4 2 0 0 2 2 2 0 BNR/Asp-box repeat Fungal_trans PF04082.18 KFX99391.1 - 8e-07 28.3 0.5 1.6e-06 27.4 0.5 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF3656 PF12392.8 KFX99391.1 - 0.031 14.9 0.0 0.07 13.8 0.0 1.5 1 0 0 1 1 1 0 Collagenase DUF2961 PF11175.8 KFX99392.1 - 7.1e-85 284.4 4.0 9.3e-85 284.0 4.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2961) Pkinase PF00069.25 KFX99401.1 - 2.7e-50 171.2 0.1 8.2e-50 169.6 0.1 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFX99401.1 - 4.5e-23 81.9 0.1 9.9e-23 80.7 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.23 KFX99401.1 - 0.00042 20.3 0.1 0.00042 20.3 0.1 2.5 2 1 1 3 3 3 1 Phosphotransferase enzyme family RIO1 PF01163.22 KFX99401.1 - 0.0034 17.0 0.2 0.0096 15.5 0.2 1.6 1 1 0 1 1 1 1 RIO1 family SNF2_N PF00176.23 KFX99402.1 - 1.9e-65 220.9 0.0 3.9e-65 219.9 0.0 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KFX99402.1 - 2.5e-20 72.9 0.0 7e-20 71.4 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ERCC3_RAD25_C PF16203.5 KFX99402.1 - 2.4e-08 33.5 0.0 4.8e-08 32.5 0.0 1.4 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase ResIII PF04851.15 KFX99402.1 - 7.1e-07 29.4 0.0 1.9e-06 28.0 0.0 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Nup88 PF10168.9 KFX99402.1 - 6.2 4.5 8.2 9.4 3.9 8.2 1.1 1 0 0 1 1 1 0 Nuclear pore component LON_substr_bdg PF02190.16 KFX99403.1 - 1e-24 87.6 0.0 1.4e-24 87.2 0.0 1.2 1 0 0 1 1 1 1 ATP-dependent protease La (LON) substrate-binding domain zf-C3HC4_2 PF13923.6 KFX99403.1 - 6.6e-12 45.1 10.5 1.2e-11 44.3 9.8 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KFX99403.1 - 2.5e-09 37.0 6.8 7.3e-09 35.5 4.5 2.6 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 KFX99403.1 - 1.6e-08 34.2 6.0 3.9e-08 33.0 6.0 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KFX99403.1 - 1.8e-08 34.1 9.9 3.9e-08 33.0 9.9 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KFX99403.1 - 3.2e-08 33.8 9.4 3.2e-08 33.8 9.4 2.1 2 1 0 2 2 2 1 Ring finger domain zf-RING_5 PF14634.6 KFX99403.1 - 2.9e-07 30.4 9.0 2.9e-07 30.4 9.0 1.8 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 KFX99403.1 - 2.8e-06 27.4 6.8 1.5e-05 25.0 7.2 2.0 1 1 1 2 2 2 1 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 KFX99403.1 - 3e-06 27.0 7.2 6.7e-06 25.9 7.2 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_10 PF16685.5 KFX99403.1 - 0.00065 19.8 3.6 0.0015 18.6 3.6 1.6 1 0 0 1 1 1 1 zinc RING finger of MSL2 zf-rbx1 PF12678.7 KFX99403.1 - 0.0013 18.9 4.8 0.0013 18.9 4.8 1.9 2 0 0 2 2 1 1 RING-H2 zinc finger domain zf-P11 PF03854.14 KFX99403.1 - 0.0018 17.9 6.8 0.0049 16.5 6.8 1.8 1 0 0 1 1 1 1 P-11 zinc finger U-box PF04564.15 KFX99403.1 - 0.0025 17.9 0.0 0.0051 17.0 0.0 1.5 1 0 0 1 1 1 1 U-box domain zf-RING_4 PF14570.6 KFX99403.1 - 0.0046 16.7 6.7 0.015 15.0 6.7 2.0 1 1 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-ANAPC11 PF12861.7 KFX99403.1 - 0.25 11.4 1.9 0.65 10.1 1.9 1.7 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger MTHFR_C PF12225.8 KFX99403.1 - 0.58 9.9 4.1 14 5.4 0.9 2.3 2 0 0 2 2 2 0 Methylene-tetrahydrofolate reductase C terminal zf-Nse PF11789.8 KFX99403.1 - 1.1 9.1 9.7 0.3 10.9 4.7 2.3 2 0 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit RRM_1 PF00076.22 KFX99404.1 - 0.0023 17.7 0.0 0.0041 16.9 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PsaN PF05479.11 KFX99405.1 - 0.032 14.4 0.0 0.064 13.4 0.0 1.5 1 0 0 1 1 1 0 Photosystem I reaction centre subunit N (PSAN or PSI-N) PPR_2 PF13041.6 KFX99406.1 - 1.1e-25 89.6 0.1 4.9e-17 61.9 0.0 4.0 4 0 0 4 4 4 2 PPR repeat family PPR_3 PF13812.6 KFX99406.1 - 4.5e-11 42.7 0.1 1e-05 25.5 0.0 3.8 4 0 0 4 4 4 2 Pentatricopeptide repeat domain PPR PF01535.20 KFX99406.1 - 6e-08 32.4 4.3 0.00057 20.0 0.1 5.3 7 0 0 7 7 7 2 PPR repeat PPR_long PF17177.4 KFX99406.1 - 2e-07 30.6 0.1 8e-07 28.6 0.0 1.9 2 0 0 2 2 2 1 Pentacotripeptide-repeat region of PRORP PPR_1 PF12854.7 KFX99406.1 - 0.0032 17.1 8.7 0.021 14.5 0.0 4.8 7 0 0 7 7 7 1 PPR repeat DNA_pol_B PF00136.21 KFX99407.1 - 1.1e-113 380.4 1.1 1.1e-113 380.4 1.1 1.5 2 0 0 2 2 2 1 DNA polymerase family B zf-DNA_Pol PF08996.10 KFX99407.1 - 2.6e-68 229.4 1.1 4.4e-68 228.7 1.1 1.4 1 0 0 1 1 1 1 DNA Polymerase alpha zinc finger DNA_pol_B_exo1 PF03104.19 KFX99407.1 - 2e-41 142.3 0.0 4.4e-41 141.1 0.0 1.6 2 0 0 2 2 2 1 DNA polymerase family B, exonuclease domain DNA_pol_alpha_N PF12254.8 KFX99407.1 - 4.1e-24 84.4 9.7 4.1e-24 84.4 9.7 2.8 2 0 0 2 2 2 1 DNA polymerase alpha subunit p180 N terminal DNA_pol_B_2 PF03175.13 KFX99407.1 - 0.011 14.6 0.0 0.024 13.5 0.0 1.4 1 0 0 1 1 1 0 DNA polymerase type B, organellar and viral CDC45 PF02724.14 KFX99407.1 - 7.7 4.7 7.9 12 4.0 7.9 1.2 1 0 0 1 1 1 0 CDC45-like protein FAD_binding_3 PF01494.19 KFX99411.1 - 2.6e-32 112.4 0.0 3.4e-32 112.0 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain SE PF08491.10 KFX99411.1 - 0.2 10.6 0.0 0.29 10.2 0.0 1.2 1 0 0 1 1 1 0 Squalene epoxidase SAGA-Tad1 PF12767.7 KFX99412.1 - 8.5e-58 195.9 0.0 1e-57 195.6 0.0 1.1 1 0 0 1 1 1 1 Transcriptional regulator of RNA polII, SAGA, subunit GCP_C_terminal PF04130.13 KFX99413.1 - 3.3e-101 338.8 0.0 5.8e-101 338.0 0.0 1.4 1 0 0 1 1 1 1 Gamma tubulin complex component C-terminal GCP_N_terminal PF17681.1 KFX99413.1 - 1.9e-83 280.6 0.0 5.2e-83 279.2 0.0 1.7 2 0 0 2 2 2 1 Gamma tubulin complex component N-terminal DUF3921 PF13060.6 KFX99413.1 - 0.071 13.2 0.1 0.2 11.7 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3921) WD40 PF00400.32 KFX99414.1 - 8.3e-32 108.7 28.9 1.2e-05 26.0 0.3 10.6 10 0 0 10 10 10 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFX99414.1 - 2.4e-19 69.4 3.4 7.2e-07 29.4 0.0 6.4 4 3 4 8 8 8 4 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KFX99414.1 - 5.4e-05 23.2 1.6 2 8.3 0.0 4.6 4 2 1 5 5 5 2 Eukaryotic translation initiation factor eIF2A Nbas_N PF15492.6 KFX99414.1 - 0.0016 17.8 2.9 2.2 7.6 0.0 4.4 4 1 1 5 5 5 1 Neuroblastoma-amplified sequence, N terminal PD40 PF07676.12 KFX99414.1 - 0.0046 16.9 2.9 3 7.9 0.0 4.4 5 0 0 5 5 5 1 WD40-like Beta Propeller Repeat Ge1_WD40 PF16529.5 KFX99414.1 - 0.022 13.8 5.0 5.1 6.0 0.2 4.3 3 2 0 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Me-amine-dh_H PF06433.11 KFX99414.1 - 0.034 13.0 0.0 0.44 9.3 0.0 2.7 3 0 0 3 3 3 0 Methylamine dehydrogenase heavy chain (MADH) DBP10CT PF08147.12 KFX99414.1 - 0.097 12.9 1.1 0.8 10.0 0.8 2.4 2 0 0 2 2 2 0 DBP10CT (NUC160) domain GspH PF12019.8 KFX99414.1 - 0.16 12.4 8.2 0.84 10.1 0.1 4.0 4 1 0 5 5 5 0 Type II transport protein GspH PhyH PF05721.13 KFX99415.1 - 2.3e-08 34.5 0.0 2.7e-08 34.3 0.0 1.0 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) DNA_pol_phi PF04931.13 KFX99421.1 - 0.095 10.8 6.9 0.11 10.5 6.9 1.0 1 0 0 1 1 1 0 DNA polymerase phi RRN3 PF05327.11 KFX99421.1 - 0.99 7.9 3.1 1.3 7.5 3.1 1.0 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 CDC45 PF02724.14 KFX99421.1 - 5.9 5.1 9.4 7.5 4.7 9.4 1.1 1 0 0 1 1 1 0 CDC45-like protein MFS_1 PF07690.16 KFX99422.1 - 5.2e-39 134.2 52.8 2e-37 128.9 32.7 2.9 2 1 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KFX99422.1 - 3.2e-15 56.0 8.3 3.2e-15 56.0 8.3 2.1 3 0 0 3 3 3 1 Sugar (and other) transporter TRI12 PF06609.13 KFX99422.1 - 4e-05 22.3 19.1 5.4e-05 21.8 19.1 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) GATase PF00117.28 KFX99423.1 - 2.6e-13 50.2 0.0 3.4e-13 49.8 0.0 1.1 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 KFX99423.1 - 0.0065 16.3 2.5 2.6 7.8 2.5 3.0 1 1 0 1 1 1 1 Peptidase C26 GATase_3 PF07685.14 KFX99423.1 - 0.031 13.9 0.0 0.043 13.4 0.0 1.2 1 0 0 1 1 1 0 CobB/CobQ-like glutamine amidotransferase domain Senescence PF06911.12 KFX99424.1 - 8.5e-56 189.2 8.0 1.2e-55 188.7 8.0 1.2 1 0 0 1 1 1 1 Senescence-associated protein Rho_GDI PF02115.17 KFX99425.1 - 6e-65 218.7 0.7 6.6e-65 218.5 0.7 1.0 1 0 0 1 1 1 1 RHO protein GDP dissociation inhibitor Metallophos PF00149.28 KFX99426.1 - 1.2e-37 130.5 0.4 1.5e-37 130.1 0.4 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 KFX99426.1 - 0.02 15.3 0.3 0.054 13.9 0.3 1.8 1 0 0 1 1 1 0 Serine-threonine protein phosphatase N-terminal domain Metallophos_2 PF12850.7 KFX99426.1 - 0.17 12.1 0.0 0.27 11.4 0.0 1.3 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain zf-CCHC PF00098.23 KFX99427.1 - 0.0017 18.4 2.8 0.0033 17.4 2.8 1.5 1 0 0 1 1 1 1 Zinc knuckle Adaptin_N PF01602.20 KFX99428.1 - 2.9e-104 349.5 0.0 3.5e-104 349.3 0.0 1.0 1 0 0 1 1 1 1 Adaptin N terminal region HEAT_2 PF13646.6 KFX99428.1 - 7.2e-14 51.9 0.4 2.7e-05 24.5 0.0 5.0 3 2 0 4 4 4 3 HEAT repeats Cnd1 PF12717.7 KFX99428.1 - 2.8e-13 50.2 0.0 3.8e-12 46.5 0.0 2.6 3 0 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 KFX99428.1 - 6.7e-10 38.4 0.0 0.053 13.8 0.0 5.6 5 0 0 5 5 5 3 HEAT repeat HEAT_EZ PF13513.6 KFX99428.1 - 0.0019 18.7 1.1 0.4 11.2 0.0 4.5 4 0 0 4 4 4 1 HEAT-like repeat VHS PF00790.19 KFX99428.1 - 0.058 13.2 1.1 63 3.4 0.0 3.9 4 0 0 4 4 4 0 VHS domain Cnd3 PF12719.7 KFX99428.1 - 0.12 11.6 0.2 0.66 9.1 0.1 2.2 2 0 0 2 2 2 0 Nuclear condensing complex subunits, C-term domain CRISPR_Cse2 PF09485.10 KFX99428.1 - 0.22 12.0 1.7 1.9 9.0 0.4 2.9 3 0 0 3 3 3 0 CRISPR-associated protein Cse2 (CRISPR_cse2) Na_Ca_ex_C PF16494.5 KFX99428.1 - 1.7 9.1 0.0 1.7 9.1 0.0 2.5 2 0 0 2 2 2 0 C-terminal extension of sodium/calcium exchanger domain Nop14 PF04147.12 KFX99428.1 - 4.4 5.4 26.1 7.4 4.6 26.1 1.3 1 0 0 1 1 1 0 Nop14-like family Pes-10 PF07149.11 KFX99429.1 - 0.054 12.5 0.5 0.072 12.1 0.5 1.1 1 0 0 1 1 1 0 Pes-10 UCR_TM PF02921.14 KFX99430.1 - 1.4e-11 44.7 0.7 1.4e-11 44.7 0.7 1.9 2 0 0 2 2 2 1 Ubiquinol cytochrome reductase transmembrane region Rieske PF00355.26 KFX99430.1 - 2.7e-11 43.2 0.0 4.8e-11 42.4 0.0 1.4 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Pectinesterase PF01095.19 KFX99431.1 - 5.1e-31 107.5 0.4 7.2e-24 84.0 0.1 2.1 2 0 0 2 2 2 2 Pectinesterase Pectate_lyase_3 PF12708.7 KFX99431.1 - 0.074 12.9 3.2 0.12 12.2 3.2 1.3 1 0 0 1 1 1 0 Pectate lyase superfamily protein Alpha-amylase PF00128.24 KFX99432.1 - 5.7e-114 381.2 0.7 1.3e-113 380.0 0.1 1.7 2 0 0 2 2 2 1 Alpha amylase, catalytic domain Malt_amylase_C PF16657.5 KFX99432.1 - 0.0003 20.8 0.1 0.0012 19.0 0.0 2.0 2 0 0 2 2 2 1 Maltogenic Amylase, C-terminal domain hDGE_amylase PF14701.6 KFX99432.1 - 0.029 13.5 0.0 0.056 12.5 0.0 1.4 1 0 0 1 1 1 0 Glycogen debranching enzyme, glucanotransferase domain Glyco_hydro_42C PF08533.10 KFX99432.1 - 0.075 12.8 0.1 2.7 7.8 0.0 2.7 3 0 0 3 3 3 0 Beta-galactosidase C-terminal domain Sugar_tr PF00083.24 KFX99433.1 - 4.3e-90 302.7 23.7 4.9e-90 302.6 23.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KFX99433.1 - 3.8e-16 59.0 35.5 7.7e-16 58.0 29.9 2.5 1 1 1 3 3 3 2 Major Facilitator Superfamily MFS_4 PF06779.14 KFX99433.1 - 2e-06 27.4 2.7 4e-06 26.4 2.7 1.5 1 0 0 1 1 1 1 Uncharacterised MFS-type transporter YbfB Fungal_trans PF04082.18 KFX99434.1 - 4.4e-12 45.6 2.3 7.5e-12 44.8 2.3 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KFX99434.1 - 2.7e-06 27.4 11.5 6.3e-06 26.2 11.5 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF2653 PF10850.8 KFX99434.1 - 0.071 13.3 0.0 2.1 8.6 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2653) Hydrolase_6 PF13344.6 KFX99435.1 - 1.3e-21 76.6 0.0 2.8e-21 75.5 0.0 1.6 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KFX99435.1 - 8.6e-19 67.4 0.0 2.5e-18 65.9 0.0 1.8 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.26 KFX99435.1 - 0.096 13.0 0.0 6.4 7.0 0.0 3.0 3 0 0 3 3 3 0 haloacid dehalogenase-like hydrolase PLA2_B PF01735.18 KFX99454.1 - 4.4e-195 648.8 0.7 5.2e-195 648.5 0.7 1.0 1 0 0 1 1 1 1 Lysophospholipase catalytic domain Cupin_2 PF07883.11 KFX99455.1 - 9.4e-05 22.1 0.1 0.0019 17.9 0.1 2.3 1 1 0 1 1 1 1 Cupin domain SWIRM-assoc_2 PF16496.5 KFX99456.1 - 0.0017 17.3 0.1 0.0017 17.3 0.1 2.7 2 1 1 3 3 3 1 SWIRM-associated domain at the N-terminal AT_hook PF02178.19 KFX99456.1 - 1.1 9.3 14.5 1.5 9.0 0.3 4.3 3 0 0 3 3 3 0 AT hook motif PBP1_TM PF14812.6 KFX99456.1 - 8.5 6.8 7.4 21 5.5 2.1 3.0 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Methyltransf_2 PF00891.18 KFX99457.1 - 3.9e-16 59.0 0.1 1e-15 57.6 0.0 1.7 2 0 0 2 2 2 1 O-methyltransferase domain Dimerisation2 PF16864.5 KFX99457.1 - 0.0068 16.4 0.1 0.017 15.1 0.1 1.7 1 1 0 1 1 1 1 Dimerisation domain Rrf2 PF02082.20 KFX99457.1 - 0.063 13.6 0.1 0.17 12.3 0.1 1.7 1 0 0 1 1 1 0 Transcriptional regulator HalX PF08663.10 KFX99457.1 - 0.14 12.5 1.3 0.26 11.6 1.3 1.4 1 0 0 1 1 1 0 HalX domain WW PF00397.26 KFX99458.1 - 0.063 13.4 6.3 0.15 12.2 6.3 1.7 1 0 0 1 1 1 0 WW domain UbiA PF01040.18 KFX99459.1 - 8.8e-59 198.8 22.8 1.3e-58 198.2 22.8 1.3 1 0 0 1 1 1 1 UbiA prenyltransferase family DUF1180 PF06679.12 KFX99459.1 - 0.69 10.3 4.5 1.3 9.4 4.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) Myb_DNA-bind_6 PF13921.6 KFX99460.1 - 9.8e-06 25.7 0.4 2.3e-05 24.6 0.4 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 KFX99460.1 - 1.4e-05 25.2 0.1 0.00013 22.0 0.0 2.2 2 0 0 2 2 2 1 Myb-like DNA-binding domain TLD PF07534.16 KFX99461.1 - 2.4e-22 79.7 0.0 1.2e-21 77.4 0.0 2.0 1 1 0 1 1 1 1 TLD DUF1773 PF08593.10 KFX99461.1 - 1.1e-12 48.7 3.7 2.9e-12 47.4 3.7 1.8 1 0 0 1 1 1 1 Domain of unknown function Goodbye PF17109.5 KFX99462.1 - 1.3e-22 80.6 0.0 8.4e-22 77.9 0.0 2.5 2 0 0 2 2 2 1 fungal STAND N-terminal Goodbye domain AAA_22 PF13401.6 KFX99462.1 - 1.6e-05 25.2 0.0 6.1e-05 23.3 0.0 2.0 1 0 0 1 1 1 1 AAA domain TPR_2 PF07719.17 KFX99462.1 - 3e-05 23.8 2.5 0.024 14.7 0.3 3.8 4 0 0 4 4 4 2 Tetratricopeptide repeat NACHT PF05729.12 KFX99462.1 - 0.00023 21.1 0.0 0.00061 19.8 0.0 1.7 1 0 0 1 1 1 1 NACHT domain KAP_NTPase PF07693.14 KFX99462.1 - 0.016 14.5 0.4 0.033 13.4 0.4 1.5 1 0 0 1 1 1 0 KAP family P-loop domain TPR_8 PF13181.6 KFX99462.1 - 0.027 14.7 0.8 1.8 9.0 0.1 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat AAA_16 PF13191.6 KFX99462.1 - 0.036 14.4 0.1 0.23 11.8 0.0 2.5 2 0 0 2 2 2 0 AAA ATPase domain TPR_16 PF13432.6 KFX99462.1 - 0.049 14.3 2.8 0.057 14.1 0.4 2.5 2 0 0 2 2 1 0 Tetratricopeptide repeat AAA_19 PF13245.6 KFX99462.1 - 0.073 13.4 0.0 1.1 9.6 0.0 2.8 3 0 0 3 3 3 0 AAA domain TPR_1 PF00515.28 KFX99462.1 - 0.16 11.8 1.4 13 5.8 0.5 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat ZZ PF00569.17 KFX99462.1 - 0.32 10.8 2.2 0.79 9.6 2.2 1.6 1 0 0 1 1 1 0 Zinc finger, ZZ type TPR_19 PF14559.6 KFX99462.1 - 0.52 10.8 4.5 0.76 10.3 0.3 3.2 4 0 0 4 4 2 0 Tetratricopeptide repeat TPR_11 PF13414.6 KFX99462.1 - 0.59 9.9 5.4 0.89 9.3 1.6 3.1 4 0 0 4 4 4 0 TPR repeat SKG6 PF08693.10 KFX99463.1 - 6.4e-05 22.3 0.1 0.00018 20.9 0.1 1.7 1 0 0 1 1 1 1 Transmembrane alpha-helix domain LuxS PF02664.15 KFX99463.1 - 1.1 8.9 4.4 32 4.2 0.1 3.3 3 0 0 3 3 3 0 S-Ribosylhomocysteinase (LuxS) Gram_pos_anchor PF00746.21 KFX99463.1 - 2.9 7.9 11.2 0.05 13.6 1.8 2.7 2 0 0 2 2 2 0 LPXTG cell wall anchor motif HA2 PF04408.23 KFX99481.1 - 1.1e-22 80.4 0.0 3.4e-22 78.8 0.0 1.9 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 KFX99481.1 - 3.4e-22 78.6 0.0 6.8e-22 77.6 0.0 1.5 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 KFX99481.1 - 8.5e-14 51.8 0.0 2.1e-13 50.6 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain S1 PF00575.23 KFX99481.1 - 6.1e-10 39.3 1.2 1.4e-09 38.2 1.2 1.6 1 0 0 1 1 1 1 S1 RNA binding domain DEAD PF00270.29 KFX99481.1 - 1.2e-06 28.4 0.3 2.9e-06 27.2 0.3 1.6 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 KFX99481.1 - 3e-06 27.5 0.1 8.1e-06 26.2 0.1 1.7 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 KFX99481.1 - 0.00013 21.8 0.1 0.00037 20.3 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 KFX99481.1 - 0.00061 20.1 0.1 0.0013 19.1 0.1 1.5 1 0 0 1 1 1 1 AAA domain T2SSE PF00437.20 KFX99481.1 - 0.001 18.2 0.1 0.0028 16.8 0.0 1.7 2 0 0 2 2 2 1 Type II/IV secretion system protein DUF2075 PF09848.9 KFX99481.1 - 0.03 13.6 0.0 0.049 12.9 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_14 PF13173.6 KFX99481.1 - 0.068 13.2 0.3 0.63 10.1 0.3 2.2 1 1 0 1 1 1 0 AAA domain SRP54 PF00448.22 KFX99481.1 - 0.089 12.4 0.1 0.2 11.2 0.1 1.6 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_33 PF13671.6 KFX99481.1 - 0.12 12.6 0.1 0.39 10.9 0.1 2.0 1 1 0 1 1 1 0 AAA domain Rib_5-P_isom_A PF06026.14 KFX99481.1 - 0.13 11.9 0.1 0.25 10.9 0.1 1.4 1 0 0 1 1 1 0 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) Cellulase PF00150.18 KFX99482.1 - 9.3e-17 61.4 4.9 1.3e-16 60.9 4.9 1.2 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) DUF4038 PF13204.6 KFX99482.1 - 2.9e-09 37.0 2.9 4.1e-09 36.5 2.9 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF4038) Glyco_hydro_2_C PF02836.17 KFX99482.1 - 3e-07 29.9 0.1 6.9e-07 28.7 0.1 1.7 1 1 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Glyco_hydro_42 PF02449.15 KFX99482.1 - 0.0058 16.0 1.0 0.0073 15.7 0.2 1.5 2 0 0 2 2 2 1 Beta-galactosidase Sec1 PF00995.23 KFX99483.1 - 2.6e-126 423.2 0.0 3.1e-126 422.9 0.0 1.0 1 0 0 1 1 1 1 Sec1 family Profilin PF00235.19 KFX99484.1 - 3.1e-47 160.0 0.7 3.6e-47 159.8 0.7 1.0 1 0 0 1 1 1 1 Profilin AAA PF00004.29 KFX99485.1 - 1.6e-52 177.4 0.0 5.3e-37 127.2 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KFX99485.1 - 9.6e-15 54.1 9.3 3.6e-11 42.7 0.1 3.1 3 0 0 3 3 3 2 AAA+ lid domain AAA_16 PF13191.6 KFX99485.1 - 1.1e-05 25.9 9.0 0.0046 17.4 3.1 4.1 3 2 0 3 3 3 2 AAA ATPase domain AAA_5 PF07728.14 KFX99485.1 - 1.8e-05 24.8 0.2 0.17 11.9 0.0 3.4 3 1 0 3 3 3 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 KFX99485.1 - 0.00032 21.0 0.6 0.44 10.8 0.2 3.6 2 2 0 2 2 2 1 AAA domain AAA_33 PF13671.6 KFX99485.1 - 0.00035 20.7 0.0 0.025 14.8 0.0 2.9 2 1 0 2 2 2 1 AAA domain Mg_chelatase PF01078.21 KFX99485.1 - 0.0051 16.2 0.8 0.77 9.1 0.1 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_28 PF13521.6 KFX99485.1 - 0.008 16.4 0.0 0.25 11.6 0.0 2.7 2 0 0 2 2 2 1 AAA domain RuvB_N PF05496.12 KFX99485.1 - 0.0092 15.7 0.0 0.29 10.9 0.0 2.9 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain Rad17 PF03215.15 KFX99485.1 - 0.047 13.6 0.0 0.16 11.9 0.0 1.8 2 0 0 2 2 2 0 Rad17 P-loop domain NACHT PF05729.12 KFX99485.1 - 0.082 12.8 1.5 0.38 10.6 0.2 2.7 3 0 0 3 3 3 0 NACHT domain AAA_14 PF13173.6 KFX99485.1 - 0.1 12.6 0.0 4.7 7.3 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_2 PF07724.14 KFX99485.1 - 0.13 12.4 0.0 0.87 9.7 0.0 2.2 2 0 0 2 2 2 0 AAA domain (Cdc48 subfamily) Zeta_toxin PF06414.12 KFX99485.1 - 0.16 11.2 0.0 1.1 8.5 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin AAA_25 PF13481.6 KFX99485.1 - 0.24 11.0 4.6 9.8 5.7 0.1 3.3 2 1 0 2 2 2 0 AAA domain MRP-L46 PF11788.8 KFX99486.1 - 2.1e-09 38.1 0.1 4.6e-09 37.0 0.1 1.6 1 0 0 1 1 1 1 39S mitochondrial ribosomal protein L46 NUDIX PF00293.28 KFX99486.1 - 0.78 9.8 5.5 0.4 10.7 0.1 2.5 1 1 1 2 2 2 0 NUDIX domain PRCC PF10253.9 KFX99487.1 - 2.1e-36 126.8 4.2 2.1e-36 126.8 4.2 2.5 3 0 0 3 3 3 1 Mitotic checkpoint regulator, MAD2B-interacting DLIC PF05783.11 KFX99487.1 - 4.4 6.0 7.3 8.3 5.1 7.3 1.4 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) CRIM PF16978.5 KFX99488.1 - 3.1e-43 147.3 0.0 5.6e-43 146.5 0.0 1.4 1 0 0 1 1 1 1 SAPK-interacting protein 1 (Sin1), middle CRIM domain SIN1_PH PF16979.5 KFX99488.1 - 4.3e-31 107.4 0.0 8e-31 106.6 0.0 1.4 1 0 0 1 1 1 1 SAPK-interacting protein 1 (Sin1), Pleckstrin-homology TUG-UBL1 PF11470.8 KFX99488.1 - 8.5e-05 22.7 0.1 0.00021 21.4 0.1 1.7 1 0 0 1 1 1 1 TUG ubiquitin-like domain RBD PF02196.15 KFX99488.1 - 0.033 14.3 0.1 0.076 13.1 0.1 1.6 1 0 0 1 1 1 0 Raf-like Ras-binding domain PBP1_TM PF14812.6 KFX99488.1 - 0.11 12.9 13.4 0.24 11.8 1.3 3.6 3 1 0 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal SRP-alpha_N PF04086.13 KFX99488.1 - 0.34 10.8 10.1 0.79 9.6 10.1 1.6 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal MFS_1 PF07690.16 KFX99489.1 - 7.8e-27 94.1 30.1 7.8e-27 94.1 30.1 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily MFS_1_like PF12832.7 KFX99489.1 - 0.81 8.5 12.0 2 7.2 9.1 2.5 2 1 0 2 2 2 0 MFS_1 like family Cyclin PF08613.11 KFX99491.1 - 3e-40 138.2 0.2 9.6e-25 87.8 0.2 2.4 2 0 0 2 2 2 2 Cyclin DUF3602 PF12223.8 KFX99492.1 - 2.2e-13 50.6 17.6 4.8e-11 43.1 4.2 2.7 2 1 1 3 3 3 2 Protein of unknown function (DUF3602) zf-C3HC4_3 PF13920.6 KFX99493.1 - 1.3e-05 25.0 9.2 1.3e-05 25.0 9.2 3.3 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) Pkinase PF00069.25 KFX99494.1 - 3.6e-42 144.5 0.0 8.7e-40 136.7 0.0 2.2 1 1 0 1 1 1 1 Protein kinase domain Ribonuc_2-5A PF06479.12 KFX99494.1 - 4.1e-31 107.8 0.0 1.1e-30 106.4 0.0 1.7 1 0 0 1 1 1 1 Ribonuclease 2-5A SWIB PF02201.18 KFX99494.1 - 1e-29 102.2 0.2 5.1e-29 100.0 0.2 2.3 1 0 0 1 1 1 1 SWIB/MDM2 domain Pkinase_Tyr PF07714.17 KFX99494.1 - 3.9e-23 82.0 0.0 3.7e-19 69.0 0.0 2.3 1 1 1 2 2 2 2 Protein tyrosine kinase DEK_C PF08766.11 KFX99494.1 - 1.4e-13 50.6 0.3 3.2e-13 49.4 0.3 1.6 1 0 0 1 1 1 1 DEK C terminal domain Pkinase_fungal PF17667.1 KFX99494.1 - 0.00025 20.0 0.8 0.0012 17.7 0.0 2.2 2 0 0 2 2 2 1 Fungal protein kinase PQQ PF01011.21 KFX99494.1 - 0.0015 18.3 3.3 0.011 15.6 0.1 3.6 3 0 0 3 3 3 1 PQQ enzyme repeat PQQ_2 PF13360.6 KFX99494.1 - 0.0017 18.0 0.5 0.017 14.7 0.5 2.4 1 1 0 1 1 1 1 PQQ-like domain Kdo PF06293.14 KFX99494.1 - 0.0045 16.4 0.0 0.0082 15.5 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KFX99494.1 - 0.013 15.5 0.3 0.058 13.3 0.2 2.0 1 1 1 2 2 2 0 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.9 KFX99494.1 - 0.099 12.2 0.0 0.19 11.2 0.0 1.4 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Peptidase_C97 PF05903.14 KFX99496.1 - 1.4e-34 119.1 0.0 1.8e-34 118.7 0.0 1.1 1 0 0 1 1 1 1 PPPDE putative peptidase domain LRAT PF04970.13 KFX99496.1 - 0.0012 19.1 0.0 0.002 18.5 0.0 1.3 1 0 0 1 1 1 1 Lecithin retinol acyltransferase DUF778 PF05608.12 KFX99496.1 - 0.076 13.4 0.1 0.12 12.7 0.1 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF778) Ribosomal_S11 PF00411.19 KFX99497.1 - 4.6e-11 43.1 0.1 1.1e-10 41.9 0.1 1.6 1 0 0 1 1 1 1 Ribosomal protein S11 Tim44 PF04280.15 KFX99498.1 - 2e-35 122.0 0.0 4.8e-35 120.8 0.0 1.7 1 0 0 1 1 1 1 Tim44-like domain Dus PF01207.17 KFX99499.1 - 5e-60 203.2 0.0 6.4e-60 202.8 0.0 1.1 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) Oxidored_FMN PF00724.20 KFX99499.1 - 0.018 14.3 0.0 0.026 13.8 0.0 1.2 1 0 0 1 1 1 0 NADH:flavin oxidoreductase / NADH oxidase family TMP-TENI PF02581.17 KFX99499.1 - 0.032 13.6 0.0 0.05 12.9 0.0 1.3 1 0 0 1 1 1 0 Thiamine monophosphate synthase Na_Ca_ex PF01699.24 KFX99500.1 - 7.2e-41 139.7 39.4 1.3e-20 73.8 19.3 2.2 2 0 0 2 2 2 2 Sodium/calcium exchanger protein DUF4337 PF14235.6 KFX99500.1 - 0.67 10.1 4.2 2.1 8.4 4.2 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) DUF3987 PF13148.6 KFX99500.1 - 8.3 5.3 9.4 13 4.6 9.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) Peptidase_S49_N PF08496.10 KFX99500.1 - 9.9 6.2 8.6 24 5.0 8.6 1.6 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Pkinase PF00069.25 KFX99501.1 - 1.2e-63 215.0 0.0 1.8e-63 214.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFX99501.1 - 2.3e-35 122.1 0.0 6.8e-30 104.2 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 KFX99501.1 - 1.2e-06 28.1 0.0 0.0017 17.7 0.0 2.2 2 0 0 2 2 2 2 Kinase-like APH PF01636.23 KFX99501.1 - 0.00057 19.9 0.0 0.00057 19.9 0.0 2.1 2 0 0 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.22 KFX99501.1 - 0.016 14.8 0.0 0.032 13.8 0.0 1.4 1 0 0 1 1 1 0 RIO1 family Haspin_kinase PF12330.8 KFX99501.1 - 0.028 13.4 0.1 0.043 12.7 0.1 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Kdo PF06293.14 KFX99501.1 - 0.058 12.7 0.1 0.11 11.8 0.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 KFX99501.1 - 2.4 6.9 6.7 2.4 6.8 0.0 2.7 2 0 0 2 2 2 0 Fungal protein kinase LRR_4 PF12799.7 KFX99507.1 - 3.4e-13 49.5 9.8 0.0038 17.6 0.0 4.1 4 0 0 4 4 4 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KFX99507.1 - 8e-11 41.5 12.7 2e-07 30.7 6.9 4.1 2 1 2 4 4 4 3 Leucine rich repeat LRR_1 PF00560.33 KFX99507.1 - 5.2e-05 23.2 9.0 29 5.7 0.3 6.7 6 0 0 6 6 6 1 Leucine Rich Repeat LRR_6 PF13516.6 KFX99507.1 - 0.00022 21.0 8.8 7.5 6.9 0.0 6.0 6 0 0 6 6 6 2 Leucine Rich repeat LRR_9 PF14580.6 KFX99507.1 - 0.0005 19.6 1.9 0.0031 17.0 0.2 2.4 2 1 1 3 3 3 2 Leucine-rich repeat Myb_DNA-binding PF00249.31 KFX99509.1 - 0.00061 19.9 1.3 0.0015 18.7 1.3 1.7 1 1 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KFX99509.1 - 0.0016 18.6 0.1 0.0025 18.0 0.1 1.3 1 0 0 1 1 1 1 Myb-like DNA-binding domain DUF498 PF04430.14 KFX99510.1 - 2.8e-32 111.0 0.0 3.9e-32 110.6 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF498/DUF598) Alk_phosphatase PF00245.20 KFX99511.1 - 1.1e-105 354.0 0.0 1.3e-105 353.7 0.0 1.1 1 0 0 1 1 1 1 Alkaline phosphatase Metalloenzyme PF01676.18 KFX99511.1 - 9.3e-05 21.9 0.0 0.00019 20.9 0.0 1.5 1 0 0 1 1 1 1 Metalloenzyme superfamily RskA PF10099.9 KFX99511.1 - 0.0087 16.4 0.0 0.044 14.1 0.0 1.9 2 0 0 2 2 2 1 Anti-sigma-K factor rskA Ribosomal_L34e PF01199.18 KFX99512.1 - 3.7e-44 148.9 2.7 4.8e-44 148.6 2.7 1.2 1 0 0 1 1 1 1 Ribosomal protein L34e Vps36-NZF-N PF16988.5 KFX99512.1 - 0.02 14.3 0.0 0.039 13.4 0.0 1.7 1 0 0 1 1 1 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain FhuF_C PF11575.8 KFX99512.1 - 0.65 10.0 4.2 4.7 7.2 0.1 2.8 3 0 0 3 3 3 0 FhuF 2Fe-2S C-terminal domain PROCN PF08083.11 KFX99513.1 - 3.9e-236 783.3 10.0 3.9e-236 783.3 10.0 2.1 2 0 0 2 2 2 1 PROCN (NUC071) domain PRP8_domainIV PF12134.8 KFX99513.1 - 8.9e-127 421.4 1.7 2e-126 420.3 1.7 1.6 1 0 0 1 1 1 1 PRP8 domain IV core U6-snRNA_bdg PF10596.9 KFX99513.1 - 2.9e-88 293.8 3.8 4.3e-88 293.3 2.3 2.2 2 0 0 2 2 2 1 U6-snRNA interacting domain of PrP8 PRO8NT PF08082.11 KFX99513.1 - 2e-81 271.3 2.6 2e-81 271.3 2.6 1.9 2 0 0 2 2 2 1 PRO8NT (NUC069), PrP8 N-terminal domain U5_2-snRNA_bdg PF10597.9 KFX99513.1 - 2e-70 235.1 0.1 4.4e-70 234.0 0.1 1.6 1 0 0 1 1 1 1 U5-snRNA binding site 2 of PrP8 RRM_4 PF10598.9 KFX99513.1 - 2.3e-48 162.5 0.3 6.2e-48 161.1 0.3 1.8 1 0 0 1 1 1 1 RNA recognition motif of the spliceosomal PrP8 PROCT PF08084.11 KFX99513.1 - 1.8e-47 160.3 0.3 5.5e-47 158.7 0.0 2.1 2 0 0 2 2 2 1 PROCT (NUC072) domain Myb_DNA-bind_6 PF13921.6 KFX99514.1 - 5.8e-12 45.7 0.1 1.4e-07 31.7 0.0 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 KFX99514.1 - 6.3e-10 39.1 0.2 0.00016 21.8 0.0 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain DUF5053 PF16476.5 KFX99514.1 - 0.19 11.4 0.1 0.48 10.1 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF5053) PhoLip_ATPase_C PF16212.5 KFX99515.1 - 1.7e-69 234.3 20.0 1.7e-69 234.3 20.0 2.2 3 0 0 3 3 3 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 KFX99515.1 - 5.6e-25 86.8 1.4 3.9e-23 80.9 0.1 2.7 2 0 0 2 2 2 1 Phospholipid-translocating ATPase N-terminal Hydrolase PF00702.26 KFX99515.1 - 1.1e-16 61.8 0.4 3.8e-05 24.1 0.0 3.3 2 1 1 3 3 3 3 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 KFX99515.1 - 1.9e-10 40.7 0.0 1.3e-09 38.0 0.0 2.3 2 0 0 2 2 2 1 Cation transport ATPase (P-type) E1-E2_ATPase PF00122.20 KFX99515.1 - 3.2e-08 33.3 0.2 9.6e-08 31.8 0.2 1.8 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase_3 PF08282.12 KFX99515.1 - 0.0011 18.8 0.0 0.0025 17.6 0.0 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase MAP17 PF15807.5 KFX99515.1 - 0.018 15.2 0.3 0.018 15.2 0.3 2.9 3 0 0 3 3 3 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 LSM PF01423.22 KFX99516.1 - 1.8e-15 56.3 0.2 2.3e-15 56.0 0.2 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 KFX99516.1 - 0.095 12.9 0.1 0.17 12.1 0.1 1.4 1 1 0 1 1 1 0 Ataxin 2 SM domain Ldi PF18566.1 KFX99517.1 - 6.2e-133 443.2 0.0 8.7e-133 442.7 0.0 1.2 1 0 0 1 1 1 1 Linalool dehydratase/isomerase PGP_phosphatase PF09419.10 KFX99517.1 - 7.9e-54 181.8 0.0 1.3e-53 181.1 0.0 1.4 1 0 0 1 1 1 1 Mitochondrial PGP phosphatase Hydrolase_like PF13242.6 KFX99517.1 - 4.9e-09 36.1 0.0 1e-08 35.1 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like Adipogenin PF15202.6 KFX99517.1 - 0.008 16.2 0.0 0.022 14.8 0.0 1.7 1 0 0 1 1 1 1 Adipogenin F-box-like_2 PF13013.6 KFX99517.1 - 0.026 14.5 0.7 0.62 10.1 0.1 2.5 2 0 0 2 2 2 0 F-box-like domain F-box-like PF12937.7 KFX99517.1 - 0.082 12.8 2.9 0.16 11.9 0.1 2.7 3 0 0 3 3 3 0 F-box-like DUF2673 PF10880.8 KFX99519.1 - 0.026 14.6 0.7 0.18 11.9 0.4 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2673) LTXXQ PF07813.12 KFX99519.1 - 0.035 14.8 0.1 0.057 14.1 0.1 1.4 1 0 0 1 1 1 0 LTXXQ motif family protein AMP-binding PF00501.28 KFX99520.1 - 6.5e-37 127.1 0.0 9.7e-37 126.6 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme ACAS_N PF16177.5 KFX99520.1 - 0.00036 20.4 0.1 0.00071 19.4 0.1 1.5 1 0 0 1 1 1 1 Acetyl-coenzyme A synthetase N-terminus Aminotran_1_2 PF00155.21 KFX99522.1 - 1.3e-60 205.6 0.0 1.9e-60 204.9 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Tmemb_18A PF09771.9 KFX99522.1 - 0.043 14.2 0.0 0.08 13.3 0.0 1.4 1 0 0 1 1 1 0 Transmembrane protein 188 VIT1 PF01988.19 KFX99523.1 - 1.4e-29 103.5 0.2 1.9e-29 103.1 0.2 1.2 1 0 0 1 1 1 1 VIT family TAXi_N PF14543.6 KFX99523.1 - 0.043 14.1 0.0 0.058 13.6 0.0 1.1 1 0 0 1 1 1 0 Xylanase inhibitor N-terminal GDP_Man_Dehyd PF16363.5 KFX99526.1 - 3.2e-08 33.4 0.2 3.2e-08 33.4 0.2 1.0 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 KFX99526.1 - 2.5e-07 30.4 0.2 2.6e-07 30.4 0.2 1.0 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.13 KFX99526.1 - 8.5e-06 25.5 0.2 8.5e-06 25.5 0.2 1.0 1 0 0 1 1 1 1 NmrA-like family 3Beta_HSD PF01073.19 KFX99526.1 - 0.0003 19.9 0.1 0.00031 19.8 0.1 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.25 KFX99526.1 - 0.00044 19.8 0.2 0.00046 19.7 0.2 1.0 1 0 0 1 1 1 1 short chain dehydrogenase NAD_binding_10 PF13460.6 KFX99526.1 - 0.0006 19.7 0.0 0.00063 19.7 0.0 1.0 1 0 0 1 1 1 1 NAD(P)H-binding NAD_binding_4 PF07993.12 KFX99526.1 - 0.0022 17.2 0.1 0.0023 17.2 0.1 1.0 1 0 0 1 1 1 1 Male sterility protein HTH_38 PF13936.6 KFX99526.1 - 0.026 14.3 0.1 0.034 13.9 0.1 1.1 1 0 0 1 1 1 0 Helix-turn-helix domain KR PF08659.10 KFX99526.1 - 0.057 13.3 0.3 0.057 13.3 0.3 1.1 1 0 0 1 1 1 0 KR domain MHYT PF03707.16 KFX99528.1 - 4.3e-23 81.2 22.2 7.8e-11 42.0 1.1 5.6 5 0 0 5 5 5 3 Bacterial signalling protein N terminal repeat Oxidored_q2 PF00420.24 KFX99528.1 - 0.11 12.1 0.9 0.33 10.6 0.9 1.8 1 0 0 1 1 1 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L TMEM154 PF15102.6 KFX99528.1 - 0.2 11.5 0.1 0.4 10.6 0.1 1.4 1 0 0 1 1 1 0 TMEM154 protein family Peptidase_A24 PF01478.18 KFX99528.1 - 5 7.6 8.5 3.4 8.1 2.0 2.8 2 0 0 2 2 2 0 Type IV leader peptidase family DUF4131 PF13567.6 KFX99528.1 - 8.8 6.0 11.1 0.37 10.4 3.4 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) Sugar_tr PF00083.24 KFX99530.1 - 2.6e-101 339.7 17.5 3e-101 339.5 17.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KFX99530.1 - 4.9e-34 117.8 17.1 6.9e-34 117.3 17.1 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Zn_clus PF00172.18 KFX99531.1 - 1.3e-10 41.2 6.0 2.5e-10 40.3 6.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KFX99531.1 - 4.7e-07 29.1 0.9 7.4e-07 28.5 0.9 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Glyco_hydro_2_C PF02836.17 KFX99532.1 - 4.7e-108 360.9 0.0 6.5e-108 360.4 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Bgal_small_N PF02929.17 KFX99532.1 - 7.1e-62 209.2 0.0 1.3e-61 208.4 0.0 1.4 1 0 0 1 1 1 1 Beta galactosidase small chain Glyco_hydro_2_N PF02837.18 KFX99532.1 - 4.8e-48 163.3 0.1 1.2e-47 162.0 0.1 1.7 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain DUF4981 PF16353.5 KFX99532.1 - 5.7e-21 74.8 0.1 1.2e-19 70.5 0.0 2.7 2 0 0 2 2 2 1 Domain of unknown function(DUF4981) Glyco_hydro_2 PF00703.21 KFX99532.1 - 4.5e-18 65.9 0.3 1.1e-17 64.7 0.3 1.7 1 0 0 1 1 1 1 Glycosyl hydrolases family 2 BetaGal_dom4_5 PF13364.6 KFX99532.1 - 0.00011 22.7 0.2 0.00083 19.9 0.0 2.6 3 0 0 3 3 3 1 Beta-galactosidase jelly roll domain NmrA PF05368.13 KFX99533.1 - 4.5e-24 85.3 0.0 6.9e-24 84.7 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KFX99533.1 - 6.6e-09 35.9 0.0 8.5e-09 35.5 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KFX99533.1 - 0.025 14.0 0.1 0.11 12.0 0.1 1.8 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family adh_short_C2 PF13561.6 KFX99534.1 - 6.9e-13 48.7 0.0 9.4e-13 48.3 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KFX99534.1 - 1.4e-12 47.5 0.0 2.1e-12 46.9 0.0 1.3 1 1 0 1 1 1 1 short chain dehydrogenase NAD_binding_10 PF13460.6 KFX99534.1 - 0.0013 18.7 0.0 0.002 18.0 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KFX99534.1 - 0.0021 17.6 0.0 0.0062 16.0 0.0 1.8 1 1 1 2 2 2 1 NAD dependent epimerase/dehydratase family NmrA PF05368.13 KFX99534.1 - 0.007 15.9 0.0 0.013 15.0 0.0 1.4 1 0 0 1 1 1 1 NmrA-like family 2-Hacid_dh_C PF02826.19 KFX99534.1 - 0.015 14.6 0.0 0.031 13.6 0.0 1.5 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain RmlD_sub_bind PF04321.17 KFX99534.1 - 0.022 13.9 0.0 0.034 13.2 0.0 1.2 1 0 0 1 1 1 0 RmlD substrate binding domain Shikimate_DH PF01488.20 KFX99534.1 - 0.034 14.2 0.0 0.054 13.6 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase BRCA-2_OB1 PF09103.10 KFX99534.1 - 0.089 12.7 0.0 0.17 11.9 0.0 1.5 1 1 0 1 1 1 0 BRCA2, oligonucleotide/oligosaccharide-binding, domain 1 3HCDH_N PF02737.18 KFX99534.1 - 0.11 12.4 0.0 0.2 11.5 0.0 1.4 1 1 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain GMC_oxred_N PF00732.19 KFX99535.1 - 1.6e-52 178.7 0.0 2.1e-52 178.4 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KFX99535.1 - 4.2e-28 98.7 0.0 1.1e-27 97.3 0.0 1.7 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.12 KFX99535.1 - 2.7e-06 26.7 0.1 4.2e-06 26.1 0.1 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_binding_2 PF00890.24 KFX99535.1 - 3.2e-06 26.5 0.0 0.00044 19.5 0.0 2.3 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.24 KFX99535.1 - 7.1e-06 25.8 1.9 0.00014 21.6 1.9 2.3 1 1 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.17 KFX99535.1 - 1.1e-05 24.8 0.1 2.3e-05 23.7 0.1 1.4 1 0 0 1 1 1 1 Thi4 family Pyr_redox_2 PF07992.14 KFX99535.1 - 5.7e-05 22.5 0.0 0.013 14.8 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KFX99535.1 - 0.00035 20.7 0.0 0.00096 19.3 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 KFX99535.1 - 0.0016 17.8 0.1 0.56 9.4 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KFX99535.1 - 0.0068 15.2 0.1 0.014 14.1 0.0 1.5 2 0 0 2 2 2 1 HI0933-like protein Trp_halogenase PF04820.14 KFX99535.1 - 0.014 14.3 0.1 0.02 13.8 0.1 1.2 1 0 0 1 1 1 0 Tryptophan halogenase NAD_binding_9 PF13454.6 KFX99535.1 - 0.018 15.0 0.2 0.11 12.5 0.0 2.1 2 0 0 2 2 2 0 FAD-NAD(P)-binding FAD_oxidored PF12831.7 KFX99535.1 - 0.18 11.1 0.5 2.5 7.4 0.4 2.1 2 0 0 2 2 2 0 FAD dependent oxidoreductase Carn_acyltransf PF00755.20 KFX99536.1 - 2e-82 277.7 0.0 3.6e-79 267.0 0.0 2.1 2 0 0 2 2 2 2 Choline/Carnitine o-acyltransferase ketoacyl-synt PF00109.26 KFX99536.1 - 5.3e-71 239.1 0.0 1.1e-70 238.1 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.21 KFX99536.1 - 1.4e-53 182.5 0.6 2.4e-53 181.7 0.6 1.4 1 0 0 1 1 1 1 Acyl transferase domain KR PF08659.10 KFX99536.1 - 4.4e-53 179.9 0.0 3.3e-52 177.0 0.0 2.5 2 0 0 2 2 2 1 KR domain PS-DH PF14765.6 KFX99536.1 - 2.9e-48 164.6 0.0 4.5e-48 164.0 0.0 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase Ketoacyl-synt_C PF02801.22 KFX99536.1 - 2.3e-38 130.9 0.0 5.9e-38 129.5 0.0 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Methyltransf_12 PF08242.12 KFX99536.1 - 7.5e-18 65.1 0.0 3.9e-17 62.8 0.0 2.4 1 0 0 1 1 1 1 Methyltransferase domain ADH_zinc_N_2 PF13602.6 KFX99536.1 - 5.6e-14 53.3 0.0 1.5e-12 48.7 0.0 3.4 3 0 0 3 3 2 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 KFX99536.1 - 2.9e-13 49.9 0.1 1.1e-12 48.1 0.0 2.1 2 0 0 2 2 1 1 Zinc-binding dehydrogenase Methyltransf_23 PF13489.6 KFX99536.1 - 1.1e-12 48.1 0.0 7.5e-12 45.4 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain KAsynt_C_assoc PF16197.5 KFX99536.1 - 1.2e-12 48.3 0.2 4.1e-08 33.7 0.0 3.3 3 0 0 3 3 3 2 Ketoacyl-synthetase C-terminal extension adh_short PF00106.25 KFX99536.1 - 3.5e-12 46.2 0.0 2.1e-11 43.7 0.0 2.3 2 0 0 2 2 2 1 short chain dehydrogenase Methyltransf_25 PF13649.6 KFX99536.1 - 1.2e-11 45.1 0.0 7.8e-11 42.5 0.0 2.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KFX99536.1 - 2.8e-11 43.9 0.0 1.5e-10 41.6 0.0 2.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KFX99536.1 - 5.3e-11 42.5 0.0 1.3e-10 41.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain PP-binding PF00550.25 KFX99536.1 - 1.7e-09 37.9 0.1 5e-09 36.4 0.1 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site adh_short_C2 PF13561.6 KFX99536.1 - 6.2e-09 35.7 0.0 2.8e-08 33.6 0.0 2.1 3 0 0 3 3 3 1 Enoyl-(Acyl carrier protein) reductase Ubie_methyltran PF01209.18 KFX99536.1 - 3.9e-05 23.1 0.0 7.8e-05 22.1 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Thiolase_N PF00108.23 KFX99536.1 - 8.2e-05 22.1 1.0 0.00067 19.1 0.1 2.2 2 0 0 2 2 2 1 Thiolase, N-terminal domain Methyltransf_16 PF10294.9 KFX99536.1 - 0.00059 19.6 0.0 0.0012 18.6 0.0 1.4 1 0 0 1 1 1 1 Lysine methyltransferase 3Beta_HSD PF01073.19 KFX99536.1 - 0.0019 17.2 0.0 0.0036 16.3 0.0 1.4 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family PriX PF18689.1 KFX99536.1 - 0.11 12.9 0.0 0.32 11.4 0.0 1.8 1 0 0 1 1 1 0 Primase X ACP_syn_III PF08545.10 KFX99536.1 - 0.11 12.3 0.1 0.35 10.7 0.1 1.9 1 0 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III GFO_IDH_MocA PF01408.22 KFX99537.1 - 3e-22 79.7 0.0 5.6e-22 78.8 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold NAD_binding_3 PF03447.16 KFX99537.1 - 0.015 16.0 0.0 0.024 15.3 0.0 1.4 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain DLIC PF05783.11 KFX99538.1 - 4.8 5.9 6.9 5.9 5.6 6.9 1.1 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) Gln-synt_C PF00120.24 KFX99541.1 - 1.2e-17 63.9 0.0 1.1e-13 51.0 0.0 2.1 2 0 0 2 2 2 2 Glutamine synthetase, catalytic domain Gln-synt_N PF03951.19 KFX99541.1 - 5e-14 51.8 0.0 7.9e-14 51.1 0.0 1.3 1 0 0 1 1 1 1 Glutamine synthetase, beta-Grasp domain Herpes_BTRF1 PF04682.12 KFX99542.1 - 0.068 12.5 1.3 0.13 11.6 1.3 1.4 1 0 0 1 1 1 0 Herpesvirus BTRF1 protein conserved region ArfGap PF01412.18 KFX99543.1 - 2.6e-37 127.5 0.1 1.1e-36 125.5 0.1 2.1 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf AA_permease PF00324.21 KFX99548.1 - 8.3e-124 413.8 35.4 9.4e-124 413.6 35.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KFX99548.1 - 2e-31 109.3 39.6 2.4e-31 109.0 39.6 1.0 1 0 0 1 1 1 1 Amino acid permease AAA_33 PF13671.6 KFX99549.1 - 2.3e-21 76.4 0.0 3e-21 76.1 0.0 1.1 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 KFX99549.1 - 2.1e-07 31.5 0.0 3e-07 31.0 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.6 KFX99549.1 - 2.5e-06 28.0 0.2 5.1e-06 26.9 0.2 1.5 1 1 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 KFX99549.1 - 0.0002 20.7 0.0 0.00026 20.3 0.0 1.1 1 0 0 1 1 1 1 Zeta toxin CPT PF07931.12 KFX99549.1 - 0.0041 17.0 0.0 0.0071 16.2 0.0 1.4 1 1 0 1 1 1 1 Chloramphenicol phosphotransferase-like protein APS_kinase PF01583.20 KFX99549.1 - 0.0053 16.7 0.1 2.8 7.8 0.0 2.2 2 0 0 2 2 2 2 Adenylylsulphate kinase NB-ARC PF00931.22 KFX99549.1 - 0.043 13.0 0.0 0.078 12.1 0.0 1.3 2 0 0 2 2 2 0 NB-ARC domain SKI PF01202.22 KFX99549.1 - 0.05 13.7 0.1 0.096 12.8 0.1 1.5 1 1 0 1 1 1 0 Shikimate kinase G-alpha PF00503.20 KFX99549.1 - 0.068 12.3 0.0 0.11 11.6 0.0 1.3 1 0 0 1 1 1 0 G-protein alpha subunit AAA_22 PF13401.6 KFX99549.1 - 0.071 13.4 0.2 0.088 13.1 0.2 1.5 1 1 0 1 1 1 0 AAA domain dNK PF01712.19 KFX99549.1 - 0.1 12.5 0.0 2.3 8.0 0.0 2.2 2 0 0 2 2 2 0 Deoxynucleoside kinase MFS_1 PF07690.16 KFX99550.1 - 1.1e-29 103.5 26.8 4.6e-16 58.7 8.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 KFX99550.1 - 3.5e-10 39.3 15.6 5.9e-08 32.0 3.5 2.1 2 0 0 2 2 2 2 MFS_1 like family MFS_2 PF13347.6 KFX99550.1 - 2.2e-07 29.8 23.2 0.014 14.0 9.3 3.0 1 1 2 3 3 3 3 MFS/sugar transport protein Sugar_tr PF00083.24 KFX99550.1 - 0.0026 16.7 6.8 0.0026 16.7 6.8 3.0 2 2 2 4 4 4 1 Sugar (and other) transporter E1-E2_ATPase PF00122.20 KFX99550.1 - 0.074 12.6 3.3 2.2 7.8 2.8 2.6 2 0 0 2 2 2 0 E1-E2 ATPase WD40 PF00400.32 KFX99551.1 - 1.2e-27 95.5 0.4 3.8e-07 30.7 0.1 6.3 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFX99551.1 - 3.9e-16 59.1 0.1 0.0054 17.0 0.0 5.3 2 2 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KFX99551.1 - 9.6e-05 22.3 0.6 0.085 12.7 0.1 3.0 1 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A Coatomer_WDAD PF04053.14 KFX99551.1 - 0.00026 20.2 0.4 0.31 10.0 0.1 2.4 1 1 1 2 2 2 2 Coatomer WD associated region Nup160 PF11715.8 KFX99551.1 - 0.00048 18.9 0.9 0.00091 18.0 0.2 1.6 1 1 0 2 2 2 1 Nucleoporin Nup120/160 PQQ_2 PF13360.6 KFX99551.1 - 0.015 14.9 0.5 0.46 10.0 0.4 2.5 1 1 1 2 2 2 0 PQQ-like domain WD40_like PF17005.5 KFX99551.1 - 0.023 14.0 0.3 0.31 10.3 0.1 2.7 1 1 2 3 3 3 0 WD40-like domain PALB2_WD40 PF16756.5 KFX99551.1 - 0.035 13.0 0.3 4.7 6.0 0.1 2.3 1 1 1 2 2 2 0 Partner and localizer of BRCA2 WD40 domain DNA_ligase_C PF17879.1 KFX99551.1 - 0.06 13.4 0.0 0.12 12.4 0.0 1.5 1 0 0 1 1 1 0 DNA ligase C-terminal domain Ge1_WD40 PF16529.5 KFX99551.1 - 0.17 10.8 2.3 5.1 6.0 0.0 2.9 3 0 0 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein FTHFS PF01268.19 KFX99552.1 - 2.7e-254 844.5 0.2 3.9e-254 844.0 0.2 1.2 1 0 0 1 1 1 1 Formate--tetrahydrofolate ligase THF_DHG_CYH_C PF02882.19 KFX99552.1 - 5.5e-67 224.0 1.8 5.5e-67 224.0 1.8 1.9 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain THF_DHG_CYH PF00763.23 KFX99552.1 - 8.2e-39 132.5 0.5 1.5e-38 131.6 0.5 1.5 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain OCD_Mu_crystall PF02423.15 KFX99552.1 - 0.0059 15.6 0.2 0.012 14.6 0.2 1.4 1 0 0 1 1 1 1 Ornithine cyclodeaminase/mu-crystallin family GTP_EFTU PF00009.27 KFX99552.1 - 0.018 14.6 0.0 0.052 13.1 0.0 1.7 1 0 0 1 1 1 0 Elongation factor Tu GTP binding domain HORMA PF02301.18 KFX99553.1 - 3.1e-34 118.4 0.1 3.6e-34 118.2 0.1 1.0 1 0 0 1 1 1 1 HORMA domain ATG101 PF07855.12 KFX99553.1 - 0.00097 19.1 0.7 0.0057 16.6 0.7 2.0 1 1 0 1 1 1 1 Autophagy-related protein 101 DUF1068 PF06364.12 KFX99553.1 - 0.011 15.6 0.2 0.018 14.9 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1068) GTP_EFTU PF00009.27 KFX99554.1 - 1.4e-49 168.3 0.0 3.4e-49 167.0 0.0 1.6 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain LepA_C PF06421.12 KFX99554.1 - 2.6e-43 146.5 5.7 4.1e-43 145.9 5.7 1.3 1 0 0 1 1 1 1 GTP-binding protein LepA C-terminus EFG_C PF00679.24 KFX99554.1 - 3.6e-20 71.8 0.0 6.6e-20 71.0 0.0 1.5 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 KFX99554.1 - 2.3e-07 31.1 0.1 5.2e-07 30.0 0.1 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 Ras PF00071.22 KFX99554.1 - 9.5e-06 25.3 0.0 3.4e-05 23.5 0.0 1.8 2 0 0 2 2 2 1 Ras family MMR_HSR1 PF01926.23 KFX99554.1 - 4.8e-05 23.4 0.0 0.00013 22.0 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 KFX99554.1 - 0.0035 16.8 0.0 0.0085 15.5 0.0 1.7 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit EFG_II PF14492.6 KFX99554.1 - 0.0091 16.1 0.0 0.019 15.0 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II MMR_HSR1_Xtn PF16897.5 KFX99554.1 - 0.011 15.7 0.0 0.025 14.6 0.0 1.5 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain RF3_C PF16658.5 KFX99554.1 - 0.072 12.9 0.0 0.47 10.3 0.0 2.2 2 0 0 2 2 2 0 Class II release factor RF3, C-terminal domain Snurportin1 PF11538.8 KFX99554.1 - 0.14 12.4 1.7 0.31 11.3 1.7 1.5 1 0 0 1 1 1 0 Snurportin1 adh_short PF00106.25 KFX99555.1 - 1.5e-14 53.9 0.4 1.4e-12 47.5 0.1 2.9 1 1 1 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 KFX99555.1 - 1e-09 38.3 0.3 1.1e-08 35.0 0.1 2.4 1 1 1 2 2 2 1 Enoyl-(Acyl carrier protein) reductase FAD_binding_3 PF01494.19 KFX99556.1 - 2.2e-07 30.5 0.1 2e-05 24.0 0.0 2.8 2 1 0 2 2 2 2 FAD binding domain bZIP_1 PF00170.21 KFX99557.1 - 0.0013 18.8 8.3 0.002 18.2 8.3 1.2 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 KFX99557.1 - 0.049 13.7 9.1 0.079 13.1 9.1 1.2 1 0 0 1 1 1 0 Basic region leucine zipper Ebola_NP PF05505.12 KFX99557.1 - 0.11 10.8 0.9 0.13 10.6 0.9 1.1 1 0 0 1 1 1 0 Ebola nucleoprotein Helo_like_N PF17111.5 KFX99559.1 - 5e-66 222.0 2.3 4.7e-64 215.6 0.1 2.3 2 0 0 2 2 2 2 Fungal N-terminal domain of STAND proteins Chalcone_2 PF16035.5 KFX99559.1 - 0.9 9.3 4.0 1.6 8.5 4.0 1.3 1 0 0 1 1 1 0 Chalcone isomerase like ArAE_1_C PF11728.8 KFX99559.1 - 1.6 8.7 9.9 2.7 8.0 9.3 1.7 2 0 0 2 2 2 0 Putative aromatic acid exporter C-terminal domain Ytp1 PF10355.9 KFX99563.1 - 7.3e-67 225.5 21.5 7.3e-67 225.5 21.5 2.7 2 2 0 2 2 2 1 Protein of unknown function (Ytp1) DUF2427 PF10348.9 KFX99563.1 - 7.2e-32 109.3 1.5 7.2e-32 109.3 1.5 2.7 4 0 0 4 4 4 1 Domain of unknown function (DUF2427) Phage_holin_3_6 PF07332.11 KFX99563.1 - 9.5 6.3 19.2 4.7 7.3 0.8 4.0 3 1 0 3 3 3 0 Putative Actinobacterial Holin-X, holin superfamily III Ammonium_transp PF00909.21 KFX99564.1 - 8.3e-116 387.0 27.2 9.7e-116 386.7 27.2 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family Pkinase PF00069.25 KFX99568.1 - 3.3e-74 249.6 0.0 4.5e-74 249.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFX99568.1 - 4.5e-30 104.8 0.0 8.2e-22 77.7 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 KFX99568.1 - 0.00013 21.4 0.0 2.7 7.2 0.0 3.2 3 0 0 3 3 3 3 Kinase-like Pkinase_fungal PF17667.1 KFX99568.1 - 0.034 12.9 0.0 0.056 12.2 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Kdo PF06293.14 KFX99568.1 - 0.042 13.2 0.0 0.075 12.4 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KFX99568.1 - 0.13 12.1 0.0 1.3 8.8 0.0 2.3 1 1 1 2 2 2 0 Phosphotransferase enzyme family Methyltransf_25 PF13649.6 KFX99569.1 - 5.1e-11 43.1 0.0 1.6e-10 41.6 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KFX99569.1 - 9.2e-11 42.3 0.0 2e-10 41.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KFX99569.1 - 2.9e-09 37.0 0.0 4.8e-09 36.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KFX99569.1 - 1.2e-05 25.1 0.0 7.3e-05 22.6 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KFX99569.1 - 4.5e-05 24.1 0.0 0.00018 22.2 0.0 2.1 2 1 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 KFX99569.1 - 0.00046 19.6 0.0 0.0017 17.8 0.0 1.8 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_32 PF13679.6 KFX99569.1 - 0.17 11.9 0.0 4.3 7.3 0.0 2.2 2 0 0 2 2 2 0 Methyltransferase domain KH_8 PF17903.1 KFX99571.1 - 1.3e-29 102.1 0.0 3.2e-29 100.8 0.0 1.7 1 0 0 1 1 1 1 Krr1 KH1 domain KH_1 PF00013.29 KFX99571.1 - 0.015 15.1 0.0 0.059 13.2 0.0 2.1 1 1 0 1 1 1 0 KH domain Myb_DNA-bind_6 PF13921.6 KFX99585.1 - 1.1e-14 54.4 1.3 3.2e-14 52.9 1.3 1.9 1 0 0 1 1 1 1 Myb-like DNA-binding domain HSA PF07529.13 KFX99585.1 - 3.6e-10 40.0 0.1 3.6e-10 40.0 0.1 4.2 5 0 0 5 5 5 1 HSA Myb_DNA-binding PF00249.31 KFX99585.1 - 1.3e-05 25.3 1.1 2.6e-05 24.3 1.1 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain DUF4113 PF13438.6 KFX99585.1 - 0.023 14.8 0.2 0.061 13.4 0.2 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4113) PALP PF00291.25 KFX99586.1 - 9.7e-32 110.5 4.4 1.3e-31 110.1 4.4 1.2 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme RhoGAP PF00620.27 KFX99590.1 - 1.4e-15 57.5 1.6 1.8e-15 57.1 0.2 1.9 2 0 0 2 2 2 1 RhoGAP domain DEP PF00610.21 KFX99590.1 - 8e-12 45.0 0.0 2.5e-11 43.5 0.0 1.9 2 0 0 2 2 2 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) FCH PF00611.23 KFX99590.1 - 4.5e-08 33.3 0.0 2e-07 31.2 0.0 2.1 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain KIP1 PF07765.12 KFX99590.1 - 0.16 12.1 0.1 3.5 7.8 0.0 3.2 3 0 0 3 3 3 0 KIP1-like protein Sec10 PF07393.11 KFX99591.1 - 2.2e-164 548.7 0.0 2.7e-164 548.4 0.0 1.1 1 0 0 1 1 1 1 Exocyst complex component Sec10 F-box-like PF12937.7 KFX99591.1 - 1.4e-07 31.3 0.0 3e-07 30.2 0.0 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KFX99591.1 - 3.9e-06 26.6 0.0 7.2e-06 25.7 0.0 1.4 1 0 0 1 1 1 1 F-box domain SNF2_N PF00176.23 KFX99592.1 - 2e-58 197.8 0.1 3.2e-58 197.1 0.1 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain zf-C3HC4_2 PF13923.6 KFX99592.1 - 2.2e-09 37.0 8.1 5.5e-09 35.7 8.1 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KFX99592.1 - 1.2e-08 34.6 4.9 1.2e-08 34.6 4.9 1.9 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KFX99592.1 - 1.3e-08 35.1 7.7 3.2e-08 33.8 7.7 1.8 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 KFX99592.1 - 4.9e-06 26.3 7.0 4.9e-06 26.3 7.0 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KFX99592.1 - 1.3e-05 25.0 5.5 3e-05 23.8 5.5 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 KFX99592.1 - 1.5e-05 24.9 6.9 3.9e-05 23.5 6.9 1.8 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.7 KFX99592.1 - 0.00016 21.9 5.2 0.00043 20.5 5.2 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 KFX99592.1 - 0.00025 21.0 5.6 0.00069 19.6 5.6 1.8 1 0 0 1 1 1 1 RING-type zinc-finger Helicase_C PF00271.31 KFX99592.1 - 0.00065 20.0 0.0 0.0015 18.9 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain PrkA PF06798.12 KFX99592.1 - 0.0018 18.0 1.5 0.0045 16.7 1.5 1.7 1 0 0 1 1 1 1 PrkA serine protein kinase C-terminal domain zf-RING_4 PF14570.6 KFX99592.1 - 0.12 12.2 2.4 0.39 10.5 2.4 1.8 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-C3HC4_4 PF15227.6 KFX99592.1 - 0.26 11.5 7.4 0.56 10.4 7.4 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_10 PF16685.5 KFX99592.1 - 0.33 11.1 3.7 0.85 9.8 3.7 1.7 1 0 0 1 1 1 0 zinc RING finger of MSL2 zf-P11 PF03854.14 KFX99592.1 - 0.66 9.7 8.7 0.13 11.9 4.6 2.0 2 0 0 2 2 2 0 P-11 zinc finger Zn_ribbon_17 PF17120.5 KFX99592.1 - 0.75 9.5 5.0 12 5.6 5.2 2.4 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type DZR PF12773.7 KFX99592.1 - 4.3 7.4 6.0 23 5.1 3.2 2.5 2 0 0 2 2 2 0 Double zinc ribbon Ribosomal_L38e PF01781.18 KFX99593.1 - 3e-32 110.5 2.7 3.6e-32 110.3 2.7 1.1 1 0 0 1 1 1 1 Ribosomal L38e protein family Ish1 PF10281.9 KFX99594.1 - 2.7e-05 24.4 0.2 4.3e-05 23.7 0.2 1.3 1 0 0 1 1 1 1 Putative stress-responsive nuclear envelope protein SAP PF02037.27 KFX99594.1 - 0.017 14.9 0.0 0.13 12.1 0.0 2.0 2 0 0 2 2 2 0 SAP domain NmrA PF05368.13 KFX99597.1 - 2.2e-60 204.2 0.7 2.7e-60 203.8 0.7 1.0 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KFX99597.1 - 1.4e-18 67.5 0.5 2.1e-18 66.9 0.5 1.2 1 0 0 1 1 1 1 NAD(P)H-binding 3Beta_HSD PF01073.19 KFX99597.1 - 1.6e-06 27.4 0.1 2.3e-06 26.9 0.1 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Sacchrp_dh_NADP PF03435.18 KFX99597.1 - 0.0086 16.3 0.2 0.015 15.6 0.2 1.5 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain PUL PF08324.11 KFX99598.1 - 1.2e-64 218.2 0.4 1.7e-64 217.7 0.4 1.2 1 0 0 1 1 1 1 PUL domain PFU PF09070.11 KFX99598.1 - 2.7e-43 146.8 0.5 5.8e-43 145.7 0.5 1.6 1 0 0 1 1 1 1 PFU (PLAA family ubiquitin binding) WD40 PF00400.32 KFX99598.1 - 1.8e-33 114.0 3.7 6.6e-06 26.8 0.0 7.7 7 0 0 7 7 7 6 WD domain, G-beta repeat WD40_like PF17005.5 KFX99598.1 - 0.024 14.0 0.0 0.08 12.2 0.0 2.0 2 1 0 2 2 2 0 WD40-like domain Peptidase_M23 PF01551.22 KFX99598.1 - 0.12 12.6 0.6 5 7.4 0.3 2.8 2 0 0 2 2 2 0 Peptidase family M23 WD40 PF00400.32 KFX99599.1 - 4.4e-23 81.1 7.1 4.1e-08 33.7 0.1 6.7 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFX99599.1 - 1.4e-07 31.7 0.0 0.13 12.6 0.0 4.0 3 1 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KFX99599.1 - 0.013 14.5 0.0 0.32 9.9 0.0 2.3 2 0 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Autophagy_N PF03986.13 KFX99600.1 - 7e-25 87.6 0.9 1e-24 87.0 0.1 1.7 2 0 0 2 2 2 1 Autophagocytosis associated protein (Atg3), N-terminal domain Autophagy_C PF10381.9 KFX99600.1 - 1.8e-14 52.9 0.4 3.1e-14 52.2 0.4 1.4 1 0 0 1 1 1 1 Autophagocytosis associated protein C-terminal Autophagy_act_C PF03987.15 KFX99600.1 - 5.2e-12 46.2 0.0 9.8e-12 45.3 0.0 1.5 1 0 0 1 1 1 1 Autophagocytosis associated protein, active-site domain PAH PF02671.21 KFX99601.1 - 0.0036 17.4 2.7 0.58 10.3 0.0 3.2 3 1 0 3 3 3 2 Paired amphipathic helix repeat F-box PF00646.33 KFX99602.1 - 0.095 12.6 0.0 0.21 11.5 0.0 1.6 1 0 0 1 1 1 0 F-box domain Pec_lyase_C PF00544.19 KFX99603.1 - 8e-45 153.0 1.3 1.2e-44 152.5 1.3 1.2 1 0 0 1 1 1 1 Pectate lyase Neurokinin_B PF03823.14 KFX99604.1 - 0.066 13.3 1.1 0.089 12.8 0.3 1.6 2 0 0 2 2 2 0 Neurokinin B ADH_N PF08240.12 KFX99605.1 - 5.2e-21 74.6 0.4 9e-21 73.8 0.4 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KFX99605.1 - 2e-16 60.2 0.3 3.9e-16 59.2 0.0 1.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KFX99605.1 - 5.4e-08 34.0 0.0 1.6e-07 32.4 0.0 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 KFX99605.1 - 0.00076 18.8 0.1 0.0012 18.1 0.1 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain CpcD PF01383.21 KFX99605.1 - 0.018 15.3 0.0 0.38 11.1 0.0 2.4 2 0 0 2 2 2 0 CpcD/allophycocyanin linker domain adh_short_C2 PF13561.6 KFX99606.1 - 1.6e-56 191.5 4.8 2e-56 191.2 4.8 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KFX99606.1 - 3e-44 150.8 4.0 3.9e-44 150.4 4.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase Abhydrolase_3 PF07859.13 KFX99607.1 - 9.1e-48 162.9 0.0 5.1e-47 160.5 0.0 1.8 2 0 0 2 2 2 1 alpha/beta hydrolase fold COesterase PF00135.28 KFX99607.1 - 6.6e-11 41.8 1.8 2.7e-10 39.7 1.8 1.7 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_6 PF12697.7 KFX99607.1 - 0.0076 16.9 0.2 0.012 16.2 0.2 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Chlorophyllase2 PF12740.7 KFX99607.1 - 0.078 11.9 0.1 0.14 11.1 0.1 1.4 1 0 0 1 1 1 0 Chlorophyllase enzyme FMO-like PF00743.19 KFX99608.1 - 9e-15 54.1 0.1 7.1e-14 51.1 0.0 1.9 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 KFX99608.1 - 2.2e-13 50.1 0.0 1e-12 48.0 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KFX99608.1 - 1.2e-10 41.1 0.0 3e-09 36.5 0.0 2.5 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.14 KFX99608.1 - 9.9e-10 38.1 0.0 2.9e-07 30.0 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KFX99608.1 - 1.2e-06 28.7 0.2 5e-06 26.7 0.0 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KFX99608.1 - 0.00058 19.5 2.8 0.13 11.9 0.1 2.6 2 1 1 3 3 3 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KFX99608.1 - 0.0061 15.7 0.0 0.011 14.8 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.17 KFX99608.1 - 0.03 13.5 0.0 0.1 11.8 0.0 1.7 2 0 0 2 2 2 0 Thi4 family Shikimate_DH PF01488.20 KFX99608.1 - 0.045 13.8 0.0 0.39 10.8 0.0 2.3 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase FAD_binding_3 PF01494.19 KFX99608.1 - 0.15 11.3 0.3 2.2 7.4 0.4 2.1 1 1 1 2 2 2 0 FAD binding domain FMO-like PF00743.19 KFX99609.1 - 7.2e-20 70.9 0.1 1.3e-18 66.8 0.0 2.3 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.6 KFX99609.1 - 3.4e-10 40.0 0.0 9.2e-10 38.6 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 KFX99609.1 - 7.7e-09 35.2 0.0 8.5e-06 25.2 0.0 2.7 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KFX99609.1 - 1e-06 28.2 0.0 0.0054 16.0 0.0 3.4 2 1 1 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KFX99609.1 - 4e-06 26.2 0.1 0.00033 19.9 0.0 2.9 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Amino_oxidase PF01593.24 KFX99609.1 - 0.0022 17.3 0.1 0.046 13.0 0.0 2.8 4 0 0 4 4 4 1 Flavin containing amine oxidoreductase NAD_binding_9 PF13454.6 KFX99609.1 - 0.0032 17.5 0.1 4.5 7.2 0.0 3.3 3 0 0 3 3 3 2 FAD-NAD(P)-binding Thi4 PF01946.17 KFX99609.1 - 0.0051 16.1 0.1 4.7 6.4 0.0 2.9 3 0 0 3 3 3 2 Thi4 family DAO PF01266.24 KFX99609.1 - 0.059 12.9 0.1 12 5.3 0.0 3.0 2 1 1 3 3 3 0 FAD dependent oxidoreductase GBP_PSP PF02425.15 KFX99609.1 - 4.5 7.0 5.0 5.2 6.8 0.6 2.8 3 0 0 3 3 3 0 Paralytic/GBP/PSP peptide adh_short PF00106.25 KFX99610.1 - 8.6e-30 103.6 0.0 1.2e-29 103.2 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KFX99610.1 - 1.7e-24 86.7 0.0 2.4e-24 86.2 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KFX99610.1 - 9.3e-09 35.4 0.0 3.3e-05 23.9 0.0 2.1 2 0 0 2 2 2 2 KR domain Epimerase PF01370.21 KFX99610.1 - 0.17 11.3 0.0 0.38 10.2 0.0 1.6 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Lactamase_B PF00753.27 KFX99611.1 - 3.3e-10 40.3 0.5 5e-10 39.7 0.5 1.3 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 KFX99611.1 - 0.0081 15.7 0.0 0.018 14.6 0.0 1.6 1 1 0 1 1 1 1 Beta-lactamase superfamily domain MFS_1 PF07690.16 KFX99612.1 - 2.2e-37 128.8 38.3 2.2e-37 128.8 38.3 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily Spherulin4 PF12138.8 KFX99613.1 - 3.3e-44 151.3 0.4 5.6e-44 150.6 0.4 1.3 1 0 0 1 1 1 1 Spherulation-specific family 4 Fungal_trans PF04082.18 KFX99613.1 - 3.3e-13 49.3 1.3 6.4e-13 48.3 1.3 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain CBM_15 PF03426.14 KFX99613.1 - 0.11 12.0 0.1 0.21 11.2 0.1 1.3 1 0 0 1 1 1 0 Carbohydrate binding domain (family 15) DUF5607 PF18355.1 KFX99615.1 - 0.063 13.7 0.3 0.21 12.0 0.3 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF5607) RR_TM4-6 PF06459.12 KFX99615.1 - 1.1 9.0 5.0 1.5 8.5 5.0 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 SOG2 PF10428.9 KFX99615.1 - 1.8 7.7 22.3 2.3 7.3 22.3 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein SAPS PF04499.15 KFX99615.1 - 2.5 6.8 4.0 3 6.5 4.0 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Plasmodium_Vir PF05795.11 KFX99615.1 - 2.6 7.4 7.4 3.4 7.0 7.4 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein PNP_UDP_1 PF01048.20 KFX99616.1 - 0.014 14.6 0.0 0.13 11.5 0.0 2.3 2 1 0 2 2 2 0 Phosphorylase superfamily adh_short_C2 PF13561.6 KFX99619.1 - 2.2e-62 210.7 1.8 3.1e-62 210.2 1.8 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KFX99619.1 - 3.8e-50 170.1 1.2 5.4e-50 169.6 1.2 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KFX99619.1 - 6.5e-12 45.7 0.4 9.4e-12 45.2 0.4 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KFX99619.1 - 1.2e-05 24.9 0.2 2.2e-05 24.0 0.2 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family PA PF02225.22 KFX99619.1 - 0.0043 17.0 0.3 0.02 14.9 0.2 2.1 2 1 0 2 2 2 1 PA domain Sacchrp_dh_NADP PF03435.18 KFX99619.1 - 0.049 13.9 0.2 0.27 11.5 0.1 2.0 1 1 1 2 2 2 0 Saccharopine dehydrogenase NADP binding domain Polysacc_synt_2 PF02719.15 KFX99619.1 - 0.05 12.7 0.1 0.07 12.2 0.1 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein GDP_Man_Dehyd PF16363.5 KFX99619.1 - 0.18 11.1 0.2 0.6 9.5 0.2 1.7 1 1 0 1 1 1 0 GDP-mannose 4,6 dehydratase PWI PF01480.17 KFX99620.1 - 6.4e-06 26.4 0.0 1.9e-05 24.9 0.0 1.7 1 1 0 1 1 1 1 PWI domain zf-CCCH PF00642.24 KFX99620.1 - 4e-05 23.4 5.7 7.7e-05 22.5 5.7 1.4 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 KFX99620.1 - 0.0044 17.0 4.6 0.0078 16.2 4.6 1.4 1 0 0 1 1 1 1 Zinc finger domain zf-CCCH_4 PF18044.1 KFX99620.1 - 0.37 10.7 6.1 0.79 9.6 6.1 1.6 1 0 0 1 1 1 0 CCCH-type zinc finger Myb_DNA-binding PF00249.31 KFX99621.1 - 0.047 13.9 0.0 0.16 12.2 0.0 1.9 1 0 0 1 1 1 0 Myb-like DNA-binding domain GTP_EFTU PF00009.27 KFX99622.1 - 1.1e-65 220.8 0.2 1.6e-65 220.3 0.2 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 KFX99622.1 - 3.8e-32 110.6 0.0 4.5e-31 107.1 0.0 2.4 1 1 1 2 2 2 1 Elongation factor G, domain IV EFG_C PF00679.24 KFX99622.1 - 5.4e-21 74.4 0.0 2.4e-20 72.3 0.0 2.0 2 0 0 2 2 2 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 KFX99622.1 - 1.2e-12 48.1 0.0 7.2e-12 45.5 0.0 2.4 3 0 0 3 3 3 1 Elongation factor Tu domain 2 EFG_II PF14492.6 KFX99622.1 - 1.4e-11 44.3 0.0 3.8e-11 42.9 0.0 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II MMR_HSR1 PF01926.23 KFX99622.1 - 0.00032 20.8 0.2 0.00065 19.8 0.2 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase Ycf54 PF10674.9 KFX99623.1 - 0.091 13.1 0.1 11 6.4 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2488) Solute_trans_a PF03619.16 KFX99624.1 - 6e-100 334.1 6.0 7.2e-100 333.9 6.0 1.1 1 0 0 1 1 1 1 Organic solute transporter Ostalpha WXG100 PF06013.12 KFX99625.1 - 0.04 14.1 1.2 0.12 12.6 0.2 2.2 2 1 0 2 2 2 0 Proteins of 100 residues with WXG COG2 PF06148.11 KFX99625.1 - 0.073 13.2 0.4 0.17 12.0 0.4 1.5 1 0 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF1664 PF07889.12 KFX99625.1 - 0.16 12.0 1.9 0.73 9.9 0.2 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) DUF4400 PF14348.6 KFX99625.1 - 0.42 10.1 1.0 0.78 9.2 1.0 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4400) bZIP_1 PF00170.21 KFX99628.1 - 3.4e-05 23.9 11.1 5.6e-05 23.2 11.1 1.3 1 0 0 1 1 1 1 bZIP transcription factor YabA PF06156.13 KFX99628.1 - 0.12 13.0 0.0 0.26 12.0 0.0 1.6 1 0 0 1 1 1 0 Initiation control protein YabA BRE1 PF08647.11 KFX99628.1 - 0.14 12.2 4.3 0.31 11.2 4.3 1.5 1 0 0 1 1 1 0 BRE1 E3 ubiquitin ligase bZIP_2 PF07716.15 KFX99628.1 - 0.54 10.4 12.8 7 6.8 12.8 2.1 1 1 0 1 1 1 0 Basic region leucine zipper eIF-3_zeta PF05091.12 KFX99630.1 - 1.1e-210 701.0 0.0 1.3e-210 700.8 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DUF569 PF04601.13 KFX99630.1 - 0.11 12.2 0.0 0.32 10.7 0.0 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF569) NARG2_C PF10505.9 KFX99630.1 - 0.17 11.4 0.0 20 4.6 0.0 2.2 2 0 0 2 2 2 0 NMDA receptor-regulated gene protein 2 C-terminus Vps16_C PF04840.12 KFX99632.1 - 0.19 10.7 0.0 0.24 10.4 0.0 1.1 1 0 0 1 1 1 0 Vps16, C-terminal region Tyrosinase PF00264.20 KFX99633.1 - 7.7e-52 176.8 1.6 1.1e-51 176.3 1.6 1.2 1 0 0 1 1 1 1 Common central domain of tyrosinase DUF1765 PF08578.10 KFX99635.1 - 7.5e-43 146.0 11.6 1.5e-42 145.0 11.6 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1765) F-box-like PF12937.7 KFX99637.1 - 0.0011 18.9 0.0 0.0032 17.3 0.0 1.9 1 0 0 1 1 1 1 F-box-like UvrD-helicase PF00580.21 KFX99645.1 - 2.2e-62 211.4 7.0 4.4e-62 210.4 2.4 2.5 2 1 0 2 2 2 1 UvrD/REP helicase N-terminal domain UvrD_C PF13361.6 KFX99645.1 - 3.8e-61 207.4 0.0 7.6e-61 206.4 0.0 1.5 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA_19 PF13245.6 KFX99645.1 - 1.7e-32 112.8 0.1 4.7e-32 111.3 0.1 1.8 1 0 0 1 1 1 1 AAA domain UvrD_C_2 PF13538.6 KFX99645.1 - 1.4e-13 50.4 0.0 7.9e-13 48.0 0.0 2.3 2 0 0 2 2 2 1 UvrD-like helicase C-terminal domain AAA_30 PF13604.6 KFX99645.1 - 9.7e-11 41.7 4.0 7.2e-06 25.9 0.3 3.1 3 0 0 3 3 3 2 AAA domain Viral_helicase1 PF01443.18 KFX99645.1 - 2.4e-05 24.2 0.0 1.4 8.6 0.0 3.4 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase AAA_11 PF13086.6 KFX99645.1 - 3.8e-05 23.6 1.7 0.00026 20.9 1.7 2.3 1 1 0 1 1 1 1 AAA domain Helicase_RecD PF05127.14 KFX99645.1 - 0.011 15.6 0.1 0.024 14.5 0.1 1.5 1 0 0 1 1 1 0 Helicase SUI1 PF01253.22 KFX99647.1 - 0.0043 17.6 0.3 0.11 13.1 0.3 2.3 2 0 0 2 2 2 1 Translation initiation factor SUI1 ELO PF01151.18 KFX99648.1 - 2.7e-07 30.4 2.4 2.7e-07 30.4 2.4 1.9 1 1 1 2 2 2 1 GNS1/SUR4 family Ribosomal_S12 PF17487.2 KFX99648.1 - 0.028 15.2 1.3 0.47 11.2 1.1 2.7 2 1 0 2 2 2 0 Ribosomal protein S12 Methyltransf_25 PF13649.6 KFX99649.1 - 7e-11 42.7 0.0 1.5e-10 41.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KFX99649.1 - 2.6e-10 40.8 0.0 4.4e-10 40.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KFX99649.1 - 5.9e-09 35.6 0.0 1e-08 34.8 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.6 KFX99649.1 - 4.8e-07 29.8 0.0 7.5e-07 29.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KFX99649.1 - 0.00022 21.1 0.0 0.00028 20.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KFX99649.1 - 0.0032 18.2 0.0 0.0069 17.1 0.0 1.5 2 0 0 2 2 2 1 Methyltransferase domain NUDE_C PF04880.13 KFX99651.1 - 2.9 8.3 5.3 4.5 7.7 5.3 1.4 1 0 0 1 1 1 0 NUDE protein, C-terminal conserved region FAD_binding_8 PF08022.12 KFX99652.1 - 7.8e-16 58.1 0.0 1.7e-15 57.0 0.0 1.6 1 0 0 1 1 1 1 FAD-binding domain Ferric_reduct PF01794.19 KFX99652.1 - 2e-14 53.8 6.1 5.1e-14 52.5 6.1 1.7 1 0 0 1 1 1 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 KFX99652.1 - 1.2e-12 48.2 0.0 2.3e-12 47.3 0.0 1.5 1 0 0 1 1 1 1 Ferric reductase NAD binding domain EF-hand_1 PF00036.32 KFX99652.1 - 0.00099 18.5 1.3 0.0022 17.4 1.3 1.6 1 0 0 1 1 1 1 EF hand EF-hand_7 PF13499.6 KFX99652.1 - 0.014 15.8 0.1 0.03 14.8 0.1 1.5 1 0 0 1 1 1 0 EF-hand domain pair EF-hand_6 PF13405.6 KFX99652.1 - 0.025 14.5 0.4 0.098 12.6 0.6 1.9 2 0 0 2 2 2 0 EF-hand domain EF-hand_5 PF13202.6 KFX99652.1 - 0.047 13.2 0.3 0.12 11.9 0.3 1.6 1 0 0 1 1 1 0 EF hand Ribonuc_red_2_N PF08471.10 KFX99653.1 - 0.051 13.7 0.1 0.21 11.8 0.0 1.9 2 0 0 2 2 2 0 Class II vitamin B12-dependent ribonucleotide reductase zinc_ribbon_15 PF17032.5 KFX99653.1 - 0.17 12.6 7.4 0.24 12.2 7.4 1.4 1 1 0 1 1 1 0 zinc-ribbon family DASH_Spc34 PF08657.10 KFX99653.1 - 0.18 11.6 5.0 0.23 11.2 5.0 1.1 1 0 0 1 1 1 0 DASH complex subunit Spc34 zinc_ribbon_2 PF13240.6 KFX99653.1 - 4.5 7.1 12.1 23 4.8 12.2 2.0 1 1 1 2 2 2 0 zinc-ribbon domain MARVEL PF01284.23 KFX99654.1 - 1e-09 38.6 14.3 1.6e-09 37.9 14.3 1.3 1 0 0 1 1 1 1 Membrane-associating domain DZR PF12773.7 KFX99654.1 - 0.0014 18.6 0.9 0.0023 17.9 0.9 1.3 1 0 0 1 1 1 1 Double zinc ribbon zinc_ribbon_2 PF13240.6 KFX99654.1 - 0.0058 16.3 3.2 0.013 15.2 3.2 1.5 1 0 0 1 1 1 1 zinc-ribbon domain zf-ribbon_3 PF13248.6 KFX99654.1 - 0.041 13.3 1.6 0.083 12.3 1.6 1.5 1 0 0 1 1 1 0 zinc-ribbon domain zinc_ribbon_15 PF17032.5 KFX99654.1 - 0.043 14.6 0.4 0.067 13.9 0.4 1.4 1 0 0 1 1 1 0 zinc-ribbon family ABC2_membrane_5 PF13346.6 KFX99654.1 - 0.41 10.2 9.9 0.015 14.8 3.9 1.5 2 0 0 2 2 2 0 ABC-2 family transporter protein Cadherin_C_2 PF16492.5 KFX99654.1 - 0.66 10.8 0.0 0.66 10.8 0.0 2.1 3 0 0 3 3 3 0 Cadherin cytoplasmic C-terminal Nudix_N_2 PF14803.6 KFX99654.1 - 3.6 7.6 5.2 8.5 6.4 0.5 2.4 2 0 0 2 2 2 0 Nudix N-terminal Glyco_hydro_31 PF01055.26 KFX99655.1 - 9.8e-105 351.3 0.0 1.3e-104 350.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.6 KFX99655.1 - 1.8e-15 57.0 0.1 5.4e-15 55.5 0.1 1.9 1 0 0 1 1 1 1 Galactose mutarotase-like CDC27 PF09507.10 KFX99656.1 - 0.00092 18.7 0.2 0.0014 18.1 0.2 1.2 1 0 0 1 1 1 1 DNA polymerase subunit Cdc27 BAR PF03114.18 KFX99657.1 - 3.8e-65 219.9 6.9 4.7e-65 219.6 6.9 1.1 1 0 0 1 1 1 1 BAR domain SH3_1 PF00018.28 KFX99657.1 - 1e-14 53.8 0.1 1.7e-14 53.1 0.1 1.4 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KFX99657.1 - 3.5e-11 42.8 0.1 5.8e-11 42.1 0.1 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 KFX99657.1 - 7.3e-09 35.2 0.0 1.6e-08 34.1 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain Vps5 PF09325.10 KFX99657.1 - 0.00086 18.9 7.6 0.44 10.0 0.0 2.2 2 0 0 2 2 2 2 Vps5 C terminal like BAR_3 PF16746.5 KFX99657.1 - 0.26 10.9 8.4 1.8 8.2 8.4 2.3 1 1 0 1 1 1 0 BAR domain of APPL family TMPIT PF07851.13 KFX99657.1 - 1.4 8.1 8.6 1 8.6 0.1 2.1 1 1 1 2 2 2 0 TMPIT-like protein Radial_spoke_3 PF06098.11 KFX99657.1 - 8 5.6 14.3 6.2 6.0 7.5 2.1 2 0 0 2 2 2 0 Radial spoke protein 3 Aminotran_5 PF00266.19 KFX99658.1 - 3e-93 312.7 0.0 3.7e-93 312.4 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 KFX99658.1 - 1.7e-06 27.6 0.0 2.4e-06 27.1 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.17 KFX99658.1 - 7.7e-05 22.2 0.1 0.00027 20.4 0.1 1.8 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family Pyridoxal_deC PF00282.19 KFX99658.1 - 0.0048 15.7 0.0 0.0079 15.0 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain CsbD PF05532.12 KFX99659.1 - 2.4e-15 56.2 28.4 1.8e-08 34.1 9.8 3.2 3 0 0 3 3 3 3 CsbD-like UPF0444 PF15475.6 KFX99659.1 - 0.2 11.9 0.5 0.2 11.9 0.5 2.6 3 0 0 3 3 3 0 Transmembrane protein C12orf23, UPF0444 Peptidase_S15 PF02129.18 KFX99662.1 - 1.6e-37 129.6 1.3 3.2e-33 115.5 0.2 2.2 1 1 1 2 2 2 2 X-Pro dipeptidyl-peptidase (S15 family) PepX_C PF08530.10 KFX99662.1 - 2.3e-24 86.6 0.0 6.7e-24 85.1 0.0 1.7 1 1 0 1 1 1 1 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain VIT PF08487.10 KFX99663.1 - 1.1e-32 112.6 1.2 9e-32 109.6 0.5 2.5 2 0 0 2 2 2 1 Vault protein inter-alpha-trypsin domain VWA_3 PF13768.6 KFX99663.1 - 7e-23 81.3 0.0 1.3e-22 80.4 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.28 KFX99663.1 - 5.5e-10 39.8 0.0 9.6e-10 39.0 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 KFX99663.1 - 5.5e-09 36.6 0.0 1.2e-08 35.6 0.0 1.6 1 0 0 1 1 1 1 von Willebrand factor type A domain VIT_2 PF13757.6 KFX99663.1 - 1e-06 28.5 0.0 2.2e-06 27.5 0.0 1.5 1 0 0 1 1 1 1 Vault protein inter-alpha-trypsin domain VWA_CoxE PF05762.14 KFX99663.1 - 0.025 14.0 0.0 0.052 12.9 0.0 1.5 1 0 0 1 1 1 0 VWA domain containing CoxE-like protein SesA PF17107.5 KFX99664.1 - 0.13 12.5 0.1 0.3 11.3 0.1 1.6 1 0 0 1 1 1 0 N-terminal domain on NACHT_NTPase and P-loop NTPases Oxysterol_BP PF01237.18 KFX99671.1 - 3.2e-64 217.1 0.2 4.8e-56 190.2 0.0 2.0 1 1 1 2 2 2 2 Oxysterol-binding protein F_bP_aldolase PF01116.20 KFX99672.1 - 1.7e-89 300.0 0.0 1.9e-89 299.8 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II Ribosomal_L9_N PF01281.19 KFX99673.1 - 5.9e-13 48.2 0.0 1.4e-12 46.9 0.0 1.7 1 0 0 1 1 1 1 Ribosomal protein L9, N-terminal domain Ribosomal_L9_C PF03948.14 KFX99673.1 - 9e-05 22.9 1.5 0.00032 21.1 0.2 2.6 3 1 0 3 3 3 1 Ribosomal protein L9, C-terminal domain UCH PF00443.29 KFX99674.1 - 9.6e-34 117.0 0.0 6.2e-29 101.3 0.0 2.1 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KFX99674.1 - 0.0058 16.3 3.4 0.52 9.8 2.6 3.0 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase DUF559 PF04480.12 KFX99674.1 - 0.12 12.3 0.9 0.22 11.4 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF559) Yip1 PF04893.17 KFX99679.1 - 1.1e-05 25.2 17.8 0.0001 22.1 7.5 2.7 2 1 1 3 3 3 2 Yip1 domain DUF4199 PF13858.6 KFX99680.1 - 0.46 10.9 13.5 0.26 11.7 1.4 2.1 1 1 0 2 2 2 0 Protein of unknown function (DUF4199) 7TM_GPCR_Sra PF02117.16 KFX99680.1 - 0.65 8.8 6.2 0.27 10.0 3.9 1.4 1 1 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Sra Sel1 PF08238.12 KFX99684.1 - 3.4e-15 56.1 7.4 0.0002 21.9 0.3 4.1 4 0 0 4 4 4 3 Sel1 repeat Complex1_LYR PF05347.15 KFX99685.1 - 0.00021 21.3 0.3 0.00021 21.3 0.3 2.1 2 0 0 2 2 2 1 Complex 1 protein (LYR family) DUF2686 PF10887.8 KFX99685.1 - 0.016 14.2 0.0 0.025 13.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2686) RRS1 PF04939.12 KFX99685.1 - 0.02 14.7 1.6 0.67 9.8 0.1 2.3 2 0 0 2 2 2 0 Ribosome biogenesis regulatory protein (RRS1) Ank_4 PF13637.6 KFX99687.1 - 4.5e-15 55.8 0.8 2e-09 37.8 0.5 3.7 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 KFX99687.1 - 1.2e-11 45.1 0.1 0.00019 22.0 0.2 3.3 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KFX99687.1 - 3.5e-10 39.2 1.7 0.013 15.9 0.0 4.6 4 0 0 4 4 4 2 Ankyrin repeat Ank PF00023.30 KFX99687.1 - 4.3e-09 36.4 1.8 0.2 12.2 0.5 4.5 4 0 0 4 4 4 3 Ankyrin repeat Ank_5 PF13857.6 KFX99687.1 - 1.4e-08 34.8 2.0 0.025 14.9 0.0 3.6 2 1 1 3 3 3 3 Ankyrin repeats (many copies) KilA-N PF04383.13 KFX99687.1 - 0.0013 18.5 0.5 0.015 15.1 0.5 2.2 1 1 0 1 1 1 1 KilA-N domain DUF3074 PF11274.8 KFX99688.1 - 3.6e-39 134.6 1.6 4.4e-39 134.4 1.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3074) Peptidase_M4_C PF02868.15 KFX99688.1 - 0.062 13.2 0.0 0.089 12.7 0.0 1.2 1 0 0 1 1 1 0 Thermolysin metallopeptidase, alpha-helical domain Formyl_trans_N PF00551.19 KFX99689.1 - 6e-38 130.4 0.0 7.3e-38 130.1 0.0 1.1 1 0 0 1 1 1 1 Formyl transferase DMRL_synthase PF00885.19 KFX99690.1 - 1.2e-49 167.7 0.0 2e-49 167.0 0.0 1.3 1 0 0 1 1 1 1 6,7-dimethyl-8-ribityllumazine synthase HTH_1 PF00126.27 KFX99691.1 - 0.19 11.7 0.9 0.33 11.0 0.9 1.3 1 0 0 1 1 1 0 Bacterial regulatory helix-turn-helix protein, lysR family SOG2 PF10428.9 KFX99701.1 - 0.18 11.0 12.0 0.17 11.1 12.0 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein Androgen_recep PF02166.16 KFX99717.1 - 0.011 14.7 6.2 0.013 14.3 6.2 1.1 1 0 0 1 1 1 0 Androgen receptor Tubulin PF00091.25 KFX99718.1 - 1e-61 208.6 0.0 1.4e-61 208.2 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 KFX99718.1 - 6e-34 116.9 0.0 9.4e-34 116.3 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 KFX99718.1 - 0.077 12.7 0.0 0.13 12.0 0.0 1.4 1 0 0 1 1 1 0 Tubulin domain Tubulin_2 PF13809.6 KFX99718.1 - 0.1 11.8 0.0 0.14 11.3 0.0 1.2 1 0 0 1 1 1 0 Tubulin like Tannase PF07519.11 KFX99720.1 - 4.3e-100 335.8 0.1 5e-100 335.6 0.1 1.0 1 0 0 1 1 1 1 Tannase and feruloyl esterase Hydrolase_4 PF12146.8 KFX99720.1 - 8.5e-05 21.9 0.0 0.001 18.4 0.0 2.2 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 KFX99720.1 - 0.0009 18.8 0.0 0.011 15.2 0.1 2.1 2 0 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_1 PF00561.20 KFX99720.1 - 0.078 12.6 0.0 1.7 8.2 0.0 2.4 2 1 1 3 3 3 0 alpha/beta hydrolase fold Abhydrolase_1 PF00561.20 KFX99721.1 - 8.8e-19 68.1 0.1 1e-18 68.0 0.1 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KFX99721.1 - 4.7e-11 43.7 1.2 6.2e-11 43.3 1.2 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KFX99721.1 - 4.9e-08 32.5 0.0 3.2e-07 29.9 0.0 1.8 1 1 1 2 2 2 1 Serine aminopeptidase, S33 Chlorophyllase PF07224.11 KFX99721.1 - 0.0069 15.4 0.0 0.01 14.9 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase EHN PF06441.12 KFX99721.1 - 0.23 11.9 0.8 1.4 9.3 0.0 2.1 2 0 0 2 2 2 0 Epoxide hydrolase N terminus Zn_clus PF00172.18 KFX99722.1 - 1.3e-05 25.2 3.1 3.2e-05 23.9 3.1 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 KFX99722.1 - 0.0061 15.4 1.0 0.011 14.5 1.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain SYCP2_ARLD PF18581.1 KFX99722.1 - 0.15 12.0 0.0 0.26 11.3 0.0 1.3 1 0 0 1 1 1 0 Synaptonemal complex 2 armadillo-repeat-like domain adh_short PF00106.25 KFX99723.1 - 1.4e-38 132.4 0.0 1.8e-38 132.0 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KFX99723.1 - 7.6e-28 97.6 0.0 1.1e-27 97.1 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF1776 PF08643.10 KFX99723.1 - 9.5e-06 25.2 0.0 2.9e-05 23.6 0.0 1.8 1 1 0 1 1 1 1 Fungal family of unknown function (DUF1776) Epimerase PF01370.21 KFX99723.1 - 0.018 14.5 0.0 0.071 12.6 0.1 1.9 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family NmrA PF05368.13 KFX99723.1 - 0.02 14.5 0.1 0.031 13.8 0.1 1.2 1 0 0 1 1 1 0 NmrA-like family PRAI PF00697.22 KFX99723.1 - 0.16 11.7 0.0 0.34 10.6 0.0 1.7 1 0 0 1 1 1 0 N-(5'phosphoribosyl)anthranilate (PRA) isomerase Acetyltransf_1 PF00583.25 KFX99724.1 - 0.046 14.0 0.0 0.072 13.3 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KFX99724.1 - 0.18 11.7 0.0 0.33 10.9 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain But2 PF09792.9 KFX99725.1 - 8.9e-09 35.9 0.5 1.2e-08 35.4 0.5 1.2 1 0 0 1 1 1 1 Ubiquitin 3 binding protein But2 C-terminal domain GP17 PF17420.2 KFX99735.1 - 0.15 12.2 0.5 0.4 10.9 0.5 1.6 1 0 0 1 1 1 0 Superinfection exclusion gene product 17 Ribosomal_S5 PF00333.20 KFX99736.1 - 6.9e-28 96.4 1.9 5.2e-27 93.6 1.0 2.4 2 0 0 2 2 2 1 Ribosomal protein S5, N-terminal domain Ribosomal_S5_C PF03719.15 KFX99736.1 - 2.8e-23 81.2 0.0 4.6e-23 80.5 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain FXMRP1_C_core PF12235.8 KFX99736.1 - 4.1 8.0 9.2 6.8 7.3 9.2 1.3 1 0 0 1 1 1 0 Fragile X-related 1 protein core C terminal Rhodanese PF00581.20 KFX99737.1 - 1.5e-17 64.1 0.0 3.4e-11 43.6 0.0 2.2 2 0 0 2 2 2 2 Rhodanese-like domain zf-ANAPC11 PF12861.7 KFX99738.1 - 3.3e-45 152.1 11.8 3.9e-45 151.8 11.8 1.1 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.7 KFX99738.1 - 1.3e-21 76.6 12.3 2e-21 76.0 12.3 1.3 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_2 PF13639.6 KFX99738.1 - 1.1e-07 32.1 16.3 2.3e-06 27.8 16.3 2.4 1 1 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.6 KFX99738.1 - 1.7e-05 24.8 8.7 0.00012 22.0 5.0 2.5 2 1 0 2 2 2 1 RING-type zinc-finger zf-C3HC4 PF00097.25 KFX99738.1 - 0.00014 21.7 14.9 0.00056 19.7 14.9 2.1 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KFX99738.1 - 0.0011 18.8 12.9 0.022 14.6 12.9 2.2 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.6 KFX99738.1 - 0.0015 18.3 2.7 0.0015 18.3 2.7 2.4 1 1 1 2 2 2 1 RING/Ubox like zinc-binding domain FANCL_C PF11793.8 KFX99738.1 - 0.002 18.2 16.8 0.035 14.3 16.8 3.0 1 1 0 1 1 1 1 FANCL C-terminal domain Zn_ribbon_17 PF17120.5 KFX99738.1 - 0.0023 17.5 11.8 0.02 14.5 11.8 2.1 1 1 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-C3HC4_2 PF13923.6 KFX99738.1 - 0.013 15.3 13.5 0.013 15.3 13.5 2.4 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-Nse PF11789.8 KFX99738.1 - 0.015 15.1 5.3 0.025 14.4 5.3 1.4 1 1 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-C3HC4_4 PF15227.6 KFX99738.1 - 0.023 14.8 9.8 0.023 14.8 9.8 2.3 1 1 1 2 2 2 0 zinc finger of C3HC4-type, RING YacG PF03884.14 KFX99738.1 - 0.083 12.6 6.1 0.18 11.6 0.2 2.7 2 0 0 2 2 2 0 DNA gyrase inhibitor YacG zf-HIT PF04438.16 KFX99738.1 - 0.093 12.6 1.0 0.093 12.6 1.0 2.4 2 0 0 2 2 2 0 HIT zinc finger Rad50_zn_hook PF04423.14 KFX99738.1 - 0.11 12.3 4.5 0.18 11.7 0.0 2.5 2 0 0 2 2 2 0 Rad50 zinc hook motif zf-RING_11 PF17123.5 KFX99738.1 - 0.19 11.5 12.3 0.52 10.1 9.0 2.8 2 1 0 2 2 2 0 RING-like zinc finger zf-C2H2_9 PF16293.5 KFX99738.1 - 0.21 11.5 4.5 2.2 8.2 0.0 3.1 2 1 1 3 3 3 0 C2H2 type zinc-finger (1 copy) Prok-RING_4 PF14447.6 KFX99738.1 - 0.35 10.8 14.4 1.8 8.5 10.8 2.4 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 DUF2256 PF10013.9 KFX99738.1 - 0.4 10.8 0.2 0.4 10.8 0.2 3.5 3 1 1 4 4 4 0 Uncharacterized protein conserved in bacteria (DUF2256) UBZ_FAAP20 PF15750.5 KFX99738.1 - 0.42 10.6 5.9 1.8 8.6 0.2 2.8 2 1 1 3 3 3 0 Ubiquitin-binding zinc-finger Opy2 PF09463.10 KFX99738.1 - 0.99 9.8 10.3 7.4 7.0 6.3 2.5 2 1 0 2 2 2 0 Opy2 protein zf-RING_5 PF14634.6 KFX99738.1 - 1 9.4 18.0 35 4.5 18.4 2.8 1 1 1 2 2 2 0 zinc-RING finger domain zf-RING-like PF08746.11 KFX99738.1 - 1.5 9.2 13.2 3.4 8.0 11.4 2.2 1 1 1 2 2 2 0 RING-like domain RINGv PF12906.7 KFX99738.1 - 2.3 8.4 13.2 5 7.3 12.3 2.1 1 1 0 1 1 1 0 RING-variant domain DZR PF12773.7 KFX99738.1 - 3.3 7.8 12.7 4.9 7.3 5.9 2.2 1 1 1 2 2 2 0 Double zinc ribbon IBR PF01485.21 KFX99740.1 - 0.018 15.2 10.3 0.018 15.2 10.3 3.4 3 0 0 3 3 3 0 IBR domain, a half RING-finger domain CBM_1 PF00734.18 KFX99742.1 - 6.1e-11 42.1 11.2 6.1e-11 42.1 11.2 2.2 2 1 0 2 2 2 1 Fungal cellulose binding domain GATA PF00320.27 KFX99748.1 - 3.4e-15 55.4 5.5 7.1e-15 54.3 5.5 1.6 1 0 0 1 1 1 1 GATA zinc finger zinc_ribbon_9 PF14369.6 KFX99748.1 - 0.4 11.0 1.6 0.86 9.9 1.6 1.5 1 0 0 1 1 1 0 zinc-ribbon zf-C2H2 PF00096.26 KFX99754.1 - 1.5e-18 66.2 28.9 3.8e-05 23.9 0.3 4.7 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KFX99754.1 - 1.1e-17 63.6 26.8 1.2e-06 28.6 0.2 5.2 5 0 0 5 5 5 4 Zinc-finger double domain zf-C2H2_4 PF13894.6 KFX99754.1 - 1.8e-08 34.5 27.0 0.016 16.0 1.1 5.0 4 0 0 4 4 4 4 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFX99754.1 - 0.0026 18.0 9.8 0.87 10.0 0.2 4.4 4 0 0 4 4 4 2 Zinc-finger double-stranded RNA-binding zf-C2H2_11 PF16622.5 KFX99754.1 - 0.01 15.6 1.5 0.01 15.6 1.5 2.6 2 0 0 2 2 2 0 zinc-finger C2H2-type zf-C2H2_8 PF15909.5 KFX99754.1 - 0.026 14.8 9.7 1.2 9.5 6.7 2.6 1 1 1 2 2 2 0 C2H2-type zinc ribbon FOXP-CC PF16159.5 KFX99754.1 - 0.047 14.3 1.3 0.047 14.3 1.3 5.0 5 1 2 7 7 7 0 FOXP coiled-coil domain Peptidase_M41 PF01434.18 KFX99755.1 - 5.1e-61 205.9 3.7 1.2e-59 201.4 3.1 2.3 2 0 0 2 2 2 1 Peptidase family M41 AAA PF00004.29 KFX99755.1 - 6.9e-42 143.0 0.0 1.9e-41 141.6 0.0 1.8 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KFX99755.1 - 3.7e-12 45.9 0.0 7.8e-12 44.8 0.0 1.6 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 KFX99755.1 - 1.2e-05 25.8 0.1 0.00026 21.4 0.1 2.8 1 1 0 1 1 1 1 AAA ATPase domain TIP49 PF06068.13 KFX99755.1 - 2.7e-05 23.6 0.0 6.3e-05 22.3 0.0 1.6 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_5 PF07728.14 KFX99755.1 - 6e-05 23.1 0.0 0.00021 21.3 0.0 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 KFX99755.1 - 0.00021 21.6 0.0 0.069 13.4 0.0 3.3 3 0 0 3 3 3 1 AAA domain RuvB_N PF05496.12 KFX99755.1 - 0.00076 19.3 0.0 0.0025 17.6 0.0 1.9 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_33 PF13671.6 KFX99755.1 - 0.0032 17.7 0.0 0.011 15.9 0.0 2.0 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 KFX99755.1 - 0.012 15.4 0.1 0.035 13.8 0.1 1.7 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_7 PF12775.7 KFX99755.1 - 0.022 14.3 0.2 0.46 10.0 0.1 2.7 2 1 0 2 2 2 0 P-loop containing dynein motor region Mg_chelatase PF01078.21 KFX99755.1 - 0.024 14.0 0.2 0.053 12.9 0.2 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_2 PF07724.14 KFX99755.1 - 0.029 14.5 0.0 0.089 12.9 0.0 1.8 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) AAA_24 PF13479.6 KFX99755.1 - 0.053 13.2 0.1 1.1 8.9 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.6 KFX99755.1 - 0.056 13.0 0.7 0.8 9.2 0.4 2.5 1 1 1 2 2 2 0 AAA domain DUF815 PF05673.13 KFX99755.1 - 0.092 11.9 0.0 0.2 10.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_28 PF13521.6 KFX99755.1 - 0.11 12.7 0.1 0.33 11.2 0.0 1.8 2 0 0 2 2 1 0 AAA domain Zeta_toxin PF06414.12 KFX99755.1 - 0.16 11.2 1.2 0.7 9.1 0.4 2.2 1 1 1 2 2 2 0 Zeta toxin TFIIB PF00382.19 KFX99756.1 - 2e-31 107.8 2.4 7.6e-18 64.3 0.1 2.9 3 0 0 3 3 3 2 Transcription factor TFIIB repeat BRF1 PF07741.13 KFX99756.1 - 3.9e-24 84.9 3.0 3.3e-23 81.9 0.4 2.5 2 0 0 2 2 2 1 Brf1-like TBP-binding domain Cyclin_N PF00134.23 KFX99756.1 - 4.9e-05 23.1 0.3 0.038 13.7 0.1 2.3 2 0 0 2 2 2 2 Cyclin, N-terminal domain Thioredoxin PF00085.20 KFX99756.1 - 0.11 12.5 0.0 0.26 11.3 0.0 1.5 1 0 0 1 1 1 0 Thioredoxin TF_Zn_Ribbon PF08271.12 KFX99756.1 - 2.1 8.0 7.3 0.096 12.2 0.6 2.2 2 0 0 2 2 2 0 TFIIB zinc-binding Cpn10 PF00166.21 KFX99757.1 - 5.9e-27 93.6 0.0 6.6e-27 93.4 0.0 1.0 1 0 0 1 1 1 1 Chaperonin 10 Kd subunit Pkinase PF00069.25 KFX99758.1 - 1.7e-47 162.0 0.0 2.7e-47 161.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Ribosomal_L11 PF00298.19 KFX99758.1 - 3.5e-26 91.5 0.2 8.5e-26 90.3 0.2 1.7 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain Ribosomal_L11_N PF03946.14 KFX99758.1 - 4.4e-25 87.3 0.1 1.1e-24 86.0 0.1 1.7 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Pkinase_Tyr PF07714.17 KFX99758.1 - 8.6e-21 74.4 0.0 1.9e-20 73.2 0.0 1.4 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.23 KFX99758.1 - 0.018 15.0 0.0 0.039 13.9 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family Haspin_kinase PF12330.8 KFX99758.1 - 0.061 12.3 0.0 0.13 11.1 0.0 1.5 1 0 0 1 1 1 0 Haspin like kinase domain Svf1_C PF17187.4 KFX99759.1 - 1.7e-59 200.4 0.4 5.3e-59 198.7 0.1 2.0 2 0 0 2 2 2 1 Svf1-like C-terminal lipocalin-like domain Svf1 PF08622.10 KFX99759.1 - 8.1e-56 188.6 0.1 1.2e-55 188.1 0.1 1.2 1 0 0 1 1 1 1 Svf1-like N-terminal lipocalin domain Glyco_hydro_31 PF01055.26 KFX99761.1 - 5.4e-34 118.1 0.1 6.1e-34 118.0 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 TPR_11 PF13414.6 KFX99765.1 - 0.026 14.2 1.1 0.068 12.9 0.3 2.0 2 0 0 2 2 2 0 TPR repeat TPR_17 PF13431.6 KFX99765.1 - 0.093 13.2 0.2 0.5 10.9 0.1 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat AAA PF00004.29 KFX99766.1 - 4.1e-20 72.5 0.0 7.4e-20 71.7 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KFX99766.1 - 0.0084 16.4 0.0 0.027 14.7 0.0 1.8 1 1 1 2 2 2 1 AAA domain MSP1_C PF07462.11 KFX99766.1 - 0.091 11.4 0.6 0.14 10.9 0.6 1.2 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus RNA_helicase PF00910.22 KFX99766.1 - 0.13 12.6 0.0 0.39 11.1 0.0 1.8 1 0 0 1 1 1 0 RNA helicase DMT_YdcZ PF04657.13 KFX99767.1 - 0.06 13.6 0.0 0.083 13.2 0.0 1.2 1 0 0 1 1 1 0 Putative inner membrane exporter, YdcZ Methyltransf_25 PF13649.6 KFX99768.1 - 1.7e-07 31.8 0.0 3.7e-07 30.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KFX99768.1 - 0.00022 21.8 0.0 0.0004 21.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KFX99768.1 - 0.21 11.4 0.0 0.36 10.6 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain p450 PF00067.22 KFX99769.1 - 2.1e-63 214.7 0.0 2.8e-63 214.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 AMP-binding PF00501.28 KFX99770.1 - 1.5e-69 234.7 0.0 1.9e-69 234.3 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KFX99770.1 - 6.5e-06 27.0 0.0 1.5e-05 25.9 0.0 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain p450 PF00067.22 KFX99771.1 - 1.9e-54 185.2 0.0 2.5e-54 184.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 SoxZ PF08770.11 KFX99771.1 - 0.009 15.8 0.0 0.019 14.7 0.0 1.5 1 0 0 1 1 1 1 Sulphur oxidation protein SoxZ Aminotran_1_2 PF00155.21 KFX99772.1 - 3.9e-38 131.6 0.0 5.1e-38 131.2 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 KFX99772.1 - 7.1e-09 35.1 0.0 1e-08 34.5 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.20 KFX99772.1 - 4.7e-06 25.4 0.0 7e-06 24.8 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme MTS PF05175.14 KFX99773.1 - 4.2e-13 49.2 0.0 3.7e-12 46.1 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.6 KFX99773.1 - 6e-09 36.5 0.0 9.4e-09 35.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KFX99773.1 - 3.3e-07 30.3 0.0 5.3e-07 29.6 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KFX99773.1 - 6.1e-07 30.0 0.0 1e-06 29.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KFX99773.1 - 1.4e-06 28.2 0.0 1.7e-06 27.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 KFX99773.1 - 5.3e-06 26.0 0.0 9.7e-06 25.2 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_12 PF08242.12 KFX99773.1 - 0.00015 22.4 0.0 0.00033 21.3 0.0 1.6 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_16 PF10294.9 KFX99773.1 - 0.0016 18.2 0.0 0.0024 17.6 0.0 1.3 1 0 0 1 1 1 1 Lysine methyltransferase TehB PF03848.14 KFX99773.1 - 0.0017 17.8 0.0 0.0028 17.1 0.0 1.2 1 0 0 1 1 1 1 Tellurite resistance protein TehB CMAS PF02353.20 KFX99773.1 - 0.038 13.3 0.0 0.24 10.6 0.0 1.9 1 1 0 1 1 1 0 Mycolic acid cyclopropane synthetase Ubie_methyltran PF01209.18 KFX99773.1 - 0.065 12.6 0.1 0.97 8.7 0.0 2.0 1 1 1 2 2 2 0 ubiE/COQ5 methyltransferase family Met_10 PF02475.16 KFX99773.1 - 0.074 12.8 0.1 0.2 11.4 0.1 1.7 1 1 1 2 2 2 0 Met-10+ like-protein NodS PF05401.11 KFX99773.1 - 0.08 12.6 0.0 0.15 11.6 0.0 1.4 1 0 0 1 1 1 0 Nodulation protein S (NodS) Methyltransf_15 PF09445.10 KFX99773.1 - 0.12 12.0 0.0 0.16 11.5 0.0 1.2 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase TENA_THI-4 PF03070.16 KFX99774.1 - 4.3e-06 26.7 0.1 0.033 14.0 0.0 2.2 2 0 0 2 2 2 2 TENA/THI-4/PQQC family AMP-binding PF00501.28 KFX99775.1 - 6.3e-72 242.5 0.0 9.5e-72 241.9 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme Condensation PF00668.20 KFX99775.1 - 6.3e-48 163.6 0.1 9.4e-48 163.0 0.1 1.2 1 0 0 1 1 1 1 Condensation domain NAD_binding_4 PF07993.12 KFX99775.1 - 2.3e-39 135.1 0.1 4e-39 134.3 0.1 1.4 1 0 0 1 1 1 1 Male sterility protein PP-binding PF00550.25 KFX99775.1 - 1.2e-18 67.2 0.1 1e-11 45.0 0.0 2.9 2 0 0 2 2 2 2 Phosphopantetheine attachment site Epimerase PF01370.21 KFX99775.1 - 2.8e-07 30.3 0.0 5.7e-07 29.2 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KFX99775.1 - 3e-05 23.2 0.0 9.9e-05 21.5 0.0 1.9 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 KFX99775.1 - 0.056 12.5 0.6 0.31 10.1 0.6 2.0 1 1 0 1 1 1 0 RmlD substrate binding domain Pkinase PF00069.25 KFX99792.1 - 1.1e-08 34.8 0.0 1.3e-06 28.0 0.0 2.8 1 1 0 1 1 1 1 Protein kinase domain DUF1768 PF08719.11 KFX99793.1 - 1e-52 178.7 0.0 1.2e-52 178.4 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1768) Ribophorin_I PF04597.14 KFX99795.1 - 2.4e-77 261.0 0.2 2.7e-77 260.8 0.2 1.0 1 0 0 1 1 1 1 Ribophorin I PetG PF02529.15 KFX99795.1 - 1.6 8.6 4.2 1.8 8.5 1.4 2.1 2 0 0 2 2 2 0 Cytochrome B6-F complex subunit 5 DNA_pol_phi PF04931.13 KFX99796.1 - 1.1e-218 728.2 6.5 1.8e-218 727.4 6.5 1.4 1 0 0 1 1 1 1 DNA polymerase phi Grg1 PF11034.8 KFX99797.1 - 1e-31 109.0 10.3 1.1e-31 108.8 10.3 1.0 1 0 0 1 1 1 1 Glucose-repressible protein Grg1 Rhodanese PF00581.20 KFX99798.1 - 8.1e-14 52.0 0.0 2e-13 50.8 0.0 1.7 1 0 0 1 1 1 1 Rhodanese-like domain DUF4110 PF13422.6 KFX99802.1 - 1.4e-13 50.7 1.1 1.5e-13 50.6 1.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4110) Proteasome PF00227.26 KFX99803.1 - 1.7e-47 161.4 0.2 2.2e-47 161.0 0.2 1.1 1 0 0 1 1 1 1 Proteasome subunit Pr_beta_C PF12465.8 KFX99803.1 - 3e-13 48.9 1.3 3e-13 48.9 1.3 1.7 2 0 0 2 2 2 1 Proteasome beta subunits C terminal DnaJ_C PF01556.18 KFX99804.1 - 1.5e-38 132.2 0.4 2.5e-38 131.5 0.4 1.4 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 KFX99804.1 - 1.8e-19 69.6 1.3 5.3e-19 68.1 1.3 1.8 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 KFX99804.1 - 4.3e-15 55.8 19.7 4.3e-15 55.8 19.7 2.5 2 0 0 2 2 2 1 DnaJ central domain Fungal_trans PF04082.18 KFX99804.1 - 2.4e-12 46.5 0.0 5.3e-12 45.3 0.0 1.5 2 0 0 2 2 2 1 Fungal specific transcription factor domain NUP214 PF16755.5 KFX99804.1 - 4.2e-10 39.4 0.1 2.3e-09 37.0 0.0 2.2 2 1 0 2 2 2 1 Nucleoporin or Nuclear pore complex subunit NUP214=Nup159 Zn_clus PF00172.18 KFX99804.1 - 9.1e-07 28.9 8.5 9.1e-07 28.9 8.5 2.8 3 0 0 3 3 3 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ANAPC4_WD40 PF12894.7 KFX99804.1 - 0.002 18.4 0.0 0.005 17.1 0.0 1.7 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KFX99805.1 - 7.5e-05 23.4 0.5 3 8.9 0.0 4.3 4 0 0 4 4 4 2 WD domain, G-beta repeat BBS2_Mid PF14783.6 KFX99805.1 - 0.051 13.6 0.0 0.67 10.0 0.0 2.4 2 0 0 2 2 2 0 Ciliary BBSome complex subunit 2, middle region NPL PF17800.1 KFX99811.1 - 1.2e-35 122.3 2.1 1.2e-35 122.3 2.1 2.4 2 2 0 2 2 2 1 Nucleoplasmin-like domain FKBP_C PF00254.28 KFX99811.1 - 3.7e-31 107.3 0.0 1e-30 105.9 0.0 1.8 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase IMS PF00817.20 KFX99812.1 - 9.8e-41 139.2 0.0 1.8e-40 138.4 0.0 1.5 1 0 0 1 1 1 1 impB/mucB/samB family CSTF2_hinge PF14327.6 KFX99812.1 - 4.5e-30 103.9 0.8 4.5e-30 103.9 0.8 2.7 3 0 0 3 3 2 1 Hinge domain of cleavage stimulation factor subunit 2 REV1_C PF16727.5 KFX99812.1 - 2.2e-27 95.3 1.2 4.3e-27 94.3 1.2 1.5 1 0 0 1 1 1 1 DNA repair protein REV1 C-terminal domain RRM_1 PF00076.22 KFX99812.1 - 5.4e-22 77.4 0.0 1.4e-21 76.0 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) UBM PF14377.6 KFX99812.1 - 1.4e-16 59.3 9.2 1.6e-07 30.5 0.3 4.3 4 0 0 4 4 4 3 Ubiquitin binding region IMS_C PF11799.8 KFX99812.1 - 1.3e-11 45.3 0.0 3.4e-11 43.9 0.0 1.7 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain BRCT_2 PF16589.5 KFX99812.1 - 8.6e-11 42.1 0.0 3.9e-10 40.0 0.0 2.1 2 0 0 2 2 2 1 BRCT domain, a BRCA1 C-terminus domain CSTF_C PF14304.6 KFX99812.1 - 9.4e-09 34.7 4.3 9.4e-09 34.7 4.3 3.8 5 0 0 5 5 5 1 Transcription termination and cleavage factor C-terminal BRCT PF00533.26 KFX99812.1 - 4.5e-08 33.3 0.0 3.7e-07 30.4 0.0 2.4 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.7 KFX99812.1 - 0.00022 21.1 0.0 0.00061 19.7 0.0 1.8 1 0 0 1 1 1 1 twin BRCT domain IMS_HHH PF11798.8 KFX99812.1 - 0.0078 16.5 0.3 0.071 13.5 0.1 2.8 2 0 0 2 2 2 1 IMS family HHH motif mCpol PF18182.1 KFX99812.1 - 0.0098 16.2 0.0 0.025 14.9 0.0 1.6 1 0 0 1 1 1 1 minimal CRISPR polymerase domain NOG1_N PF17835.1 KFX99812.1 - 0.11 12.4 0.0 0.39 10.7 0.0 1.8 2 0 0 2 2 2 0 NOG1 N-terminal helical domain RRM_7 PF16367.5 KFX99812.1 - 0.14 12.3 0.0 0.32 11.1 0.0 1.6 1 0 0 1 1 1 0 RNA recognition motif DUF1805 PF08827.11 KFX99812.1 - 0.16 12.3 0.0 0.91 9.9 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1805) Band_7 PF01145.25 KFX99813.1 - 3.6e-21 76.0 3.1 5.7e-21 75.3 3.1 1.4 1 1 0 1 1 1 1 SPFH domain / Band 7 family ubiquitin PF00240.23 KFX99814.1 - 1.8e-26 91.7 0.2 2e-26 91.5 0.2 1.0 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 KFX99814.1 - 6.6e-14 51.5 0.2 7.2e-14 51.4 0.2 1.0 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 KFX99814.1 - 5.2e-05 23.6 0.1 0.00014 22.2 0.1 1.7 1 1 0 1 1 1 1 Ubiquitin-like domain TBK1_ULD PF18396.1 KFX99814.1 - 0.0013 18.6 0.0 0.0015 18.4 0.0 1.1 1 0 0 1 1 1 1 TANK binding kinase 1 ubiquitin-like domain SnoaL PF07366.12 KFX99815.1 - 0.0028 17.4 0.0 0.0051 16.6 0.0 1.5 1 0 0 1 1 1 1 SnoaL-like polyketide cyclase Elongin_A PF06881.11 KFX99816.1 - 2.7e-30 105.0 0.9 2.7e-30 105.0 0.9 2.0 2 0 0 2 2 2 1 RNA polymerase II transcription factor SIII (Elongin) subunit A DUF3333 PF11812.8 KFX99816.1 - 0.088 13.0 1.6 8.8 6.5 0.0 2.8 2 1 1 3 3 3 0 Domain of unknown function (DUF3333) DEAD PF00270.29 KFX99827.1 - 1.1e-31 109.9 0.1 2.2e-31 109.0 0.0 1.5 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KFX99827.1 - 4e-25 88.3 0.0 9.8e-25 87.1 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KFX99827.1 - 0.0001 22.4 0.0 0.00017 21.7 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_30 PF13604.6 KFX99827.1 - 0.039 13.7 0.0 0.069 12.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain Peptidase_M10_C PF08548.11 KFX99827.1 - 0.092 12.6 0.0 0.21 11.5 0.0 1.5 2 0 0 2 2 2 0 Peptidase M10 serralysin C terminal FCH PF00611.23 KFX99828.1 - 6.4e-26 90.5 0.0 6.4e-26 90.5 0.0 2.4 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain SH3_9 PF14604.6 KFX99828.1 - 6.6e-24 83.5 1.4 2e-14 53.2 0.1 2.5 2 0 0 2 2 2 2 Variant SH3 domain SH3_1 PF00018.28 KFX99828.1 - 3.5e-16 58.5 0.4 9.3e-08 31.6 0.1 2.4 2 0 0 2 2 2 2 SH3 domain C1_1 PF00130.22 KFX99828.1 - 2.4e-15 56.1 5.6 3.8e-15 55.5 5.6 1.3 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) SH3_2 PF07653.17 KFX99828.1 - 1.2e-06 28.1 0.0 0.013 15.1 0.0 2.4 2 0 0 2 2 2 2 Variant SH3 domain SH3_3 PF08239.11 KFX99828.1 - 2.5e-05 24.5 1.1 0.0015 18.8 0.4 2.6 2 0 0 2 2 2 1 Bacterial SH3 domain SH3_10 PF17902.1 KFX99828.1 - 0.00088 19.3 0.0 1.4 9.0 0.0 2.7 2 0 0 2 2 2 2 SH3 domain C1_2 PF03107.16 KFX99828.1 - 0.00095 19.4 1.9 0.0017 18.7 1.9 1.4 1 0 0 1 1 1 1 C1 domain USP8_interact PF08941.10 KFX99828.1 - 0.57 10.0 5.2 2.8 7.7 0.5 2.6 3 0 0 3 3 3 0 USP8 interacting zf-RING_9 PF13901.6 KFX99828.1 - 0.64 10.0 5.9 0.34 10.9 0.4 2.2 2 0 0 2 2 2 0 Putative zinc-RING and/or ribbon Ku_C PF03730.14 KFX99828.1 - 1.4 9.7 7.9 2 9.1 2.3 2.8 2 0 0 2 2 2 0 Ku70/Ku80 C-terminal arm HIP1_clath_bdg PF16515.5 KFX99828.1 - 4.8 7.9 11.3 8.6 7.0 0.2 3.1 2 1 0 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 FapA PF03961.13 KFX99828.1 - 4.9 5.6 7.2 0.52 8.9 2.3 1.7 2 0 0 2 2 2 0 Flagellar Assembly Protein A Glyco_hydro_72 PF03198.14 KFX99829.1 - 3.9e-131 437.0 0.2 4.8e-131 436.7 0.2 1.0 1 0 0 1 1 1 1 Glucanosyltransferase Cellulase PF00150.18 KFX99829.1 - 0.00033 20.2 0.0 0.0024 17.3 0.0 2.2 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) DUF1349 PF07081.11 KFX99830.1 - 5.7e-29 101.1 0.1 7.1e-29 100.8 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1349) Asp PF00026.23 KFX99838.1 - 7e-45 153.8 1.1 1.6e-44 152.6 1.1 1.6 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KFX99838.1 - 1.1e-07 32.3 2.9 3.2e-06 27.5 2.9 2.3 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 KFX99838.1 - 0.033 14.8 0.2 5.6 7.7 0.0 2.8 3 0 0 3 3 3 0 Aspartyl protease ADH_zinc_N PF00107.26 KFX99839.1 - 2e-14 53.7 0.1 3.8e-14 52.8 0.1 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KFX99839.1 - 1.7e-05 24.6 0.6 9.8e-05 22.2 0.0 2.6 3 1 0 3 3 3 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 KFX99839.1 - 0.00042 21.4 0.0 0.002 19.2 0.0 2.0 2 1 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N_2 PF16884.5 KFX99839.1 - 0.018 14.9 0.0 0.066 13.1 0.0 2.0 2 1 0 2 2 2 0 N-terminal domain of oxidoreductase CAP59_mtransfer PF11735.8 KFX99840.1 - 3e-67 226.8 0.0 3.8e-67 226.5 0.0 1.1 1 0 0 1 1 1 1 Cryptococcal mannosyltransferase 1 Amidohydro_1 PF01979.20 KFX99841.1 - 2.7e-55 188.1 0.0 4.7e-55 187.3 0.0 1.4 1 0 0 1 1 1 1 Amidohydrolase family PPR_2 PF13041.6 KFX99841.1 - 3.1e-18 65.7 4.6 7.1e-06 26.1 0.1 7.4 6 1 1 7 7 7 3 PPR repeat family PPR_long PF17177.4 KFX99841.1 - 3.4e-14 52.7 0.5 1.1e-06 28.1 0.0 3.9 2 1 2 4 4 4 2 Pentacotripeptide-repeat region of PRORP Amidohydro_3 PF07969.11 KFX99841.1 - 5.4e-12 45.9 0.0 1.6e-09 37.8 0.0 2.5 2 0 0 2 2 2 2 Amidohydrolase family PPR PF01535.20 KFX99841.1 - 1e-11 44.2 10.5 0.62 10.4 0.0 9.6 10 0 0 10 10 10 4 PPR repeat PPR_3 PF13812.6 KFX99841.1 - 8.6e-11 41.8 1.8 0.0015 18.5 0.0 6.1 5 1 1 6 6 6 3 Pentatricopeptide repeat domain Zn_clus PF00172.18 KFX99841.1 - 1.9e-07 31.1 9.3 3.2e-07 30.3 9.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PPR_1 PF12854.7 KFX99841.1 - 0.00019 21.0 0.0 0.46 10.2 0.0 4.0 4 0 0 4 4 4 1 PPR repeat TPR_1 PF00515.28 KFX99841.1 - 2.1 8.3 6.1 36 4.4 0.0 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat SRP68 PF16969.5 KFX99842.1 - 2.5e-192 640.8 2.2 2.9e-192 640.6 2.2 1.0 1 0 0 1 1 1 1 RNA-binding signal recognition particle 68 PMEI PF04043.15 KFX99842.1 - 0.041 14.2 5.5 0.054 13.8 1.7 2.6 2 0 0 2 2 2 0 Plant invertase/pectin methylesterase inhibitor FA_hydroxylase PF04116.13 KFX99852.1 - 2.9e-23 82.7 15.4 2.9e-23 82.7 15.4 2.2 2 0 0 2 2 2 2 Fatty acid hydroxylase superfamily DASH_Dad2 PF08654.10 KFX99875.1 - 0.011 16.1 0.5 0.16 12.4 0.3 2.2 1 1 1 2 2 2 0 DASH complex subunit Dad2 DUF3825 PF12873.7 KFX99875.1 - 0.025 14.0 0.2 0.031 13.7 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3825) COG5 PF10392.9 KFX99875.1 - 0.047 13.9 2.5 0.4 10.9 0.7 2.2 1 1 1 2 2 2 0 Golgi transport complex subunit 5 Cauli_AT PF03233.13 KFX99875.1 - 0.049 13.6 0.8 0.11 12.4 0.5 1.5 1 1 0 1 1 1 0 Aphid transmission protein VGPC1_C PF16799.5 KFX99875.1 - 0.096 12.7 1.1 0.38 10.8 0.1 2.5 3 0 0 3 3 3 0 C-terminal membrane-localisation domain of ion-channel, VCN1 CorA PF01544.18 KFX99875.1 - 0.15 11.3 5.7 0.35 10.1 5.7 1.5 1 1 0 1 1 1 0 CorA-like Mg2+ transporter protein AF0941-like PF14591.6 KFX99875.1 - 0.19 12.3 2.8 16 6.1 1.6 2.1 1 1 1 2 2 2 0 AF0941-like DUF1664 PF07889.12 KFX99875.1 - 0.28 11.2 2.2 0.69 10.0 2.2 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) TraF_2 PF13729.6 KFX99875.1 - 0.54 9.6 3.5 0.76 9.1 1.4 1.7 1 1 1 2 2 2 0 F plasmid transfer operon, TraF, protein HSBP1 PF06825.12 KFX99875.1 - 1.1 9.2 8.1 4.8 7.1 0.3 2.9 2 1 1 3 3 3 0 Heat shock factor binding protein 1 Lipase_3 PF01764.25 KFX99876.1 - 2.1e-18 66.5 0.0 1.8e-14 53.8 0.0 2.4 2 0 0 2 2 2 2 Lipase (class 3) Abhydrolase_6 PF12697.7 KFX99876.1 - 0.003 18.2 1.1 0.0072 17.0 1.1 1.7 1 0 0 1 1 1 1 Alpha/beta hydrolase family Acetyltransf_1 PF00583.25 KFX99877.1 - 1.2e-11 44.8 0.1 2.1e-11 44.1 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KFX99877.1 - 2.5e-09 37.1 0.0 4.3e-09 36.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KFX99877.1 - 5.6e-09 36.3 0.6 1.1e-08 35.4 0.6 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Tetraspanin PF00335.20 KFX99877.1 - 0.00063 19.5 5.1 0.0008 19.2 4.4 1.6 2 0 0 2 2 2 1 Tetraspanin family DUF2721 PF11026.8 KFX99877.1 - 0.095 12.6 0.9 0.2 11.6 0.9 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2721) DUF4191 PF13829.6 KFX99877.1 - 0.57 9.5 0.0 0.57 9.5 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4191) zf-RING_2 PF13639.6 KFX99878.1 - 6.2e-12 45.7 2.2 1.2e-11 44.8 2.2 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.6 KFX99878.1 - 7.4e-08 32.3 0.6 1.5e-07 31.3 0.6 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 KFX99878.1 - 1e-06 28.5 1.8 3.9e-06 26.6 2.0 1.8 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KFX99878.1 - 1.3e-06 28.2 1.0 2.2e-06 27.5 1.0 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 KFX99878.1 - 1.6e-06 27.9 3.0 9.9e-06 25.3 3.1 2.0 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 KFX99878.1 - 1.7e-06 28.2 4.2 5.5e-06 26.6 4.3 1.8 1 1 1 2 2 2 1 RING-H2 zinc finger domain Prok-RING_4 PF14447.6 KFX99878.1 - 4.1e-06 26.6 2.0 0.00041 20.1 2.7 2.4 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 zf-C3HC4 PF00097.25 KFX99878.1 - 3.9e-05 23.4 1.2 0.00014 21.6 1.4 1.8 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 KFX99878.1 - 0.0012 19.0 2.5 0.0051 17.0 2.5 2.0 1 1 0 1 1 1 1 zinc finger of C3HC4-type, RING FANCL_C PF11793.8 KFX99878.1 - 0.0077 16.4 1.8 0.027 14.6 1.8 1.9 1 1 0 1 1 1 1 FANCL C-terminal domain Zn_ribbon_17 PF17120.5 KFX99878.1 - 0.016 14.8 0.6 0.039 13.6 0.6 1.6 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-ANAPC11 PF12861.7 KFX99878.1 - 0.024 14.7 0.6 0.024 14.7 0.6 1.9 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger Rad50_zn_hook PF04423.14 KFX99878.1 - 0.031 14.1 0.3 9.4 6.2 0.0 2.3 2 0 0 2 2 2 0 Rad50 zinc hook motif zf-RING_4 PF14570.6 KFX99878.1 - 0.11 12.3 3.1 0.83 9.5 0.3 2.2 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain Zn-ribbon_8 PF09723.10 KFX99878.1 - 0.14 12.3 1.5 7.4 6.8 0.3 2.4 2 0 0 2 2 2 0 Zinc ribbon domain Ribosomal_L14e PF01929.17 KFX99879.1 - 6.3e-33 113.1 2.5 9.5e-33 112.5 2.5 1.3 1 0 0 1 1 1 1 Ribosomal protein L14 KOW PF00467.29 KFX99879.1 - 0.00023 21.0 0.9 0.00023 21.0 0.9 1.6 2 0 0 2 2 2 1 KOW motif Prot_ATP_ID_OB PF16450.5 KFX99879.1 - 0.071 13.1 0.0 0.12 12.3 0.0 1.5 1 0 0 1 1 1 0 Proteasomal ATPase OB C-terminal domain NAC PF01849.18 KFX99880.1 - 1.4e-23 82.6 0.3 3.5e-23 81.3 0.1 1.8 2 0 0 2 2 2 1 NAC domain MoeA_N PF03453.17 KFX99880.1 - 0.015 15.1 1.0 0.02 14.6 0.6 1.7 1 1 1 2 2 2 0 MoeA N-terminal region (domain I and II) GEMIN8 PF15348.6 KFX99880.1 - 0.053 13.8 7.9 0.55 10.5 2.7 2.1 2 0 0 2 2 2 0 Gemini of Cajal bodies-associated protein 8 Myc_N PF01056.18 KFX99880.1 - 7.5 6.3 11.5 16 5.3 11.6 1.6 1 1 0 1 1 1 0 Myc amino-terminal region Mt_ATP-synt_D PF05873.12 KFX99881.1 - 1.8e-22 79.9 1.0 2.2e-22 79.6 1.0 1.1 1 0 0 1 1 1 1 ATP synthase D chain, mitochondrial (ATP5H) E3_UbLigase_R4 PF13764.6 KFX99881.1 - 0.0069 14.6 0.8 0.0078 14.4 0.8 1.0 1 0 0 1 1 1 1 E3 ubiquitin-protein ligase UBR4 DUF3544 PF12064.8 KFX99881.1 - 0.039 14.2 0.3 0.05 13.9 0.3 1.1 1 0 0 1 1 1 0 Protein kinase C-binding protein 1 KASH_CCD PF14662.6 KFX99881.1 - 0.077 12.8 4.3 0.69 9.7 1.2 2.1 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 or KASH LXG PF04740.12 KFX99881.1 - 0.097 12.4 2.9 0.13 12.0 2.9 1.2 1 0 0 1 1 1 0 LXG domain of WXG superfamily DUF4515 PF14988.6 KFX99881.1 - 0.14 12.0 6.1 0.52 10.1 1.9 2.2 1 1 0 2 2 2 0 Domain of unknown function (DUF4515) RasGAP_C PF03836.15 KFX99881.1 - 0.23 11.6 3.1 0.31 11.2 0.8 2.0 1 1 0 2 2 2 0 RasGAP C-terminus APG6_N PF17675.1 KFX99881.1 - 1.5 9.3 6.4 7.5 7.1 6.4 1.9 1 1 0 1 1 1 0 Apg6 coiled-coil region Mpv17_PMP22 PF04117.12 KFX99882.1 - 2.7e-13 49.9 0.1 5.7e-13 48.9 0.1 1.6 1 0 0 1 1 1 1 Mpv17 / PMP22 family DUF2530 PF10745.9 KFX99882.1 - 0.32 11.3 1.9 0.34 11.2 0.4 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2530) Epimerase PF01370.21 KFX99883.1 - 2.1e-09 37.2 0.2 1.8e-08 34.2 0.2 2.1 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 KFX99883.1 - 1.6e-08 34.7 0.0 2.2e-08 34.2 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 KFX99883.1 - 1.3e-06 28.2 0.0 1.9e-06 27.6 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family 3Beta_HSD PF01073.19 KFX99883.1 - 4.6e-05 22.6 0.0 0.00058 18.9 0.0 2.1 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family TrkA_N PF02254.18 KFX99883.1 - 0.0062 16.8 0.1 0.013 15.8 0.1 1.5 1 0 0 1 1 1 1 TrkA-N domain AlaDh_PNT_C PF01262.21 KFX99883.1 - 0.0089 15.3 0.1 0.015 14.6 0.1 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_4 PF07993.12 KFX99883.1 - 0.01 15.0 0.5 0.024 13.8 0.2 1.7 1 1 1 2 2 2 0 Male sterility protein ApbA PF02558.16 KFX99883.1 - 0.012 15.2 0.1 0.023 14.3 0.1 1.5 1 1 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Pyr_redox PF00070.27 KFX99883.1 - 0.014 16.0 0.1 0.029 14.9 0.1 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase F420_oxidored PF03807.17 KFX99883.1 - 0.053 14.1 0.1 0.15 12.6 0.1 1.9 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.15 KFX99883.1 - 0.085 13.0 0.0 0.14 12.3 0.0 1.3 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase GDP_Man_Dehyd PF16363.5 KFX99883.1 - 0.085 12.2 0.1 4.5 6.6 0.0 2.3 2 1 0 2 2 2 0 GDP-mannose 4,6 dehydratase Shikimate_DH PF01488.20 KFX99883.1 - 0.14 12.2 0.0 0.24 11.5 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase 3HCDH_N PF02737.18 KFX99883.1 - 0.15 11.9 0.0 0.23 11.3 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain p450 PF00067.22 KFX99884.1 - 1.3e-65 222.0 0.0 1.4e-65 221.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 HgmA PF04209.13 KFX99885.1 - 4.5e-198 658.2 0.1 5.1e-198 658.0 0.1 1.0 1 0 0 1 1 1 1 homogentisate 1,2-dioxygenase Dabb PF07876.12 KFX99886.1 - 1.1e-11 45.2 0.1 1.2e-11 45.0 0.1 1.1 1 0 0 1 1 1 1 Stress responsive A/B Barrel Domain DUF4286 PF14114.6 KFX99886.1 - 0.033 14.7 0.2 5.1 7.6 0.0 2.1 1 1 0 2 2 2 0 Domain of unknown function (DUF4286) ERCC4 PF02732.15 KFX99887.1 - 5.7e-19 68.9 0.0 1.1e-18 67.9 0.0 1.5 1 0 0 1 1 1 1 ERCC4 domain CorA PF01544.18 KFX99890.1 - 9.4e-08 31.7 0.0 1.6e-07 31.0 0.0 1.3 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein ApoL PF05461.11 KFX99890.1 - 0.13 11.6 0.5 0.19 11.0 0.5 1.2 1 0 0 1 1 1 0 Apolipoprotein L DDE_Tnp_ISL3 PF01610.17 KFX99890.1 - 0.19 11.4 0.0 0.31 10.7 0.0 1.3 1 0 0 1 1 1 0 Transposase Ribonuc_P_40 PF08584.11 KFX99901.1 - 4e-59 200.3 0.0 5.1e-59 199.9 0.0 1.1 1 0 0 1 1 1 1 Ribonuclease P 40kDa (Rpp40) subunit Ank_5 PF13857.6 KFX99902.1 - 1.7e-11 44.1 0.3 6.5e-09 35.9 0.2 2.6 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 KFX99902.1 - 2.6e-08 34.3 0.1 3.1e-07 30.9 0.1 1.9 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KFX99902.1 - 1.5e-07 31.8 0.0 3.9e-06 27.3 0.1 2.3 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFX99902.1 - 2.4e-05 24.4 0.8 0.00088 19.6 0.1 3.2 3 1 0 3 3 3 1 Ankyrin repeat Ank PF00023.30 KFX99902.1 - 0.043 14.3 0.0 0.47 11.0 0.0 2.6 3 0 0 3 3 3 0 Ankyrin repeat YusW PF14039.6 KFX99902.1 - 0.05 14.1 0.6 2.1 8.9 0.1 2.5 3 0 0 3 3 3 0 YusW-like protein tRNA_lig_CPD PF08302.11 KFX99903.1 - 2.8e-86 289.1 0.1 3.8e-86 288.7 0.1 1.2 1 0 0 1 1 1 1 Fungal tRNA ligase phosphodiesterase domain RNA_lig_T4_1 PF09511.10 KFX99903.1 - 4.1e-84 281.9 0.0 7.5e-84 281.0 0.0 1.5 1 0 0 1 1 1 1 RNA ligase tRNA_lig_kinase PF08303.11 KFX99903.1 - 2.9e-57 193.4 0.3 5.4e-57 192.5 0.3 1.5 1 0 0 1 1 1 1 tRNA ligase kinase domain RNA_ligase PF09414.10 KFX99903.1 - 0.014 15.7 0.0 0.031 14.6 0.0 1.6 1 0 0 1 1 1 0 RNA ligase AAA_18 PF13238.6 KFX99903.1 - 0.036 14.6 0.1 0.46 11.0 0.0 2.9 2 1 0 2 2 2 0 AAA domain CAP_GLY PF01302.25 KFX99904.1 - 1.3e-17 63.5 0.3 2.7e-17 62.6 0.3 1.5 1 0 0 1 1 1 1 CAP-Gly domain LRR_4 PF12799.7 KFX99904.1 - 8.8e-06 26.0 11.5 0.8 10.2 0.2 5.1 4 1 1 5 5 5 2 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 KFX99904.1 - 2.1e-05 24.1 0.6 0.15 11.5 0.1 3.4 3 0 0 3 3 3 2 Leucine-rich repeat LRR_8 PF13855.6 KFX99904.1 - 0.00016 21.4 8.7 0.17 11.7 0.6 4.3 4 1 0 4 4 4 2 Leucine rich repeat LRR_6 PF13516.6 KFX99904.1 - 0.0088 16.0 10.1 6.9 7.0 0.2 5.9 7 0 0 7 7 7 1 Leucine Rich repeat Torus PF16131.5 KFX99904.1 - 0.017 15.8 0.0 0.058 14.1 0.0 1.9 1 0 0 1 1 1 0 Torus domain zf-CCCH PF00642.24 KFX99904.1 - 0.026 14.4 3.4 0.047 13.6 3.4 1.4 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) APC_u15 PF16636.5 KFX99904.1 - 3.8 8.0 9.2 0.36 11.3 1.3 3.1 2 0 0 2 2 2 0 Unstructured region on APC between APC_crr regions 5 and 6 SF3A2 PF16835.5 KFX99905.1 - 3e-37 126.9 0.1 4.4e-37 126.3 0.1 1.3 1 0 0 1 1 1 1 Pre-mRNA-splicing factor SF3a complex subunit 2 (Prp11) zf-met PF12874.7 KFX99905.1 - 1.1e-05 25.6 0.5 2.1e-05 24.8 0.5 1.5 1 0 0 1 1 1 1 Zinc-finger of C2H2 type PRP4 PF08799.11 KFX99905.1 - 0.061 12.9 1.5 0.11 12.1 1.5 1.5 1 0 0 1 1 1 0 pre-mRNA processing factor 4 (PRP4) like Pkinase PF00069.25 KFX99906.1 - 8.6e-59 199.1 0.0 1.1e-57 195.4 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFX99906.1 - 1.7e-26 93.1 0.0 1.1e-20 74.0 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Haspin_kinase PF12330.8 KFX99906.1 - 3e-05 23.2 0.0 4.2e-05 22.7 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 KFX99906.1 - 0.00048 20.1 3.4 0.0086 16.0 0.2 2.9 2 1 1 3 3 3 1 Phosphotransferase enzyme family Kdo PF06293.14 KFX99906.1 - 0.00063 19.2 0.0 0.0016 17.8 0.0 1.6 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 KFX99906.1 - 0.00081 18.8 0.0 0.0018 17.7 0.0 1.6 1 0 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.11 KFX99906.1 - 0.091 11.8 0.0 0.15 11.1 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Tim54 PF11711.8 KFX99907.1 - 4.7e-136 453.5 0.0 5.7e-136 453.2 0.0 1.1 1 0 0 1 1 1 1 Inner membrane protein import complex subunit Tim54 NARP1 PF12569.8 KFX99908.1 - 4.2e-198 659.4 26.1 2.1e-196 653.8 20.5 2.2 2 0 0 2 2 2 2 NMDA receptor-regulated protein 1 TPR_16 PF13432.6 KFX99908.1 - 2.2e-16 60.2 25.3 0.0051 17.4 0.1 8.8 8 2 2 10 10 7 5 Tetratricopeptide repeat TPR_19 PF14559.6 KFX99908.1 - 1.7e-14 54.1 34.0 0.00049 20.5 3.6 7.7 9 0 0 9 9 6 4 Tetratricopeptide repeat TPR_14 PF13428.6 KFX99908.1 - 1.2e-13 50.6 30.2 0.0048 17.6 0.0 11.4 7 3 5 12 12 11 3 Tetratricopeptide repeat TPR_2 PF07719.17 KFX99908.1 - 6.9e-13 47.6 38.5 9.9e-05 22.2 0.1 10.7 11 1 0 11 11 10 4 Tetratricopeptide repeat TPR_17 PF13431.6 KFX99908.1 - 9.9e-13 47.5 8.4 0.00027 21.1 0.0 7.1 7 0 0 7 7 6 3 Tetratricopeptide repeat TPR_11 PF13414.6 KFX99908.1 - 3.3e-12 45.9 9.4 6.1e-06 25.8 0.1 6.0 5 0 0 5 5 5 3 TPR repeat TPR_1 PF00515.28 KFX99908.1 - 3.4e-11 42.5 30.9 2.3e-06 27.2 0.2 8.9 9 1 0 9 9 9 3 Tetratricopeptide repeat ANAPC3 PF12895.7 KFX99908.1 - 9.2e-11 41.8 20.1 5.3e-05 23.4 0.6 5.7 4 3 2 6 6 6 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.6 KFX99908.1 - 4.1e-10 39.1 32.7 9.4e-05 22.3 0.1 8.6 9 0 0 9 9 7 3 Tetratricopeptide repeat TPR_9 PF13371.6 KFX99908.1 - 4.2e-10 39.6 5.0 0.0013 18.8 0.2 5.6 5 2 0 5 5 5 2 Tetratricopeptide repeat TPR_12 PF13424.6 KFX99908.1 - 1.4e-08 34.9 23.0 0.066 13.5 2.5 7.9 7 1 0 7 7 7 3 Tetratricopeptide repeat TPR_7 PF13176.6 KFX99908.1 - 0.0083 16.1 16.7 9.2 6.6 0.1 7.3 7 1 1 8 8 7 0 Tetratricopeptide repeat YcaO_C PF18381.1 KFX99908.1 - 0.024 14.6 0.6 0.1 12.5 0.1 2.4 3 0 0 3 3 2 0 YcaO cyclodehydratase C-terminal domain Fis1_TPR_C PF14853.6 KFX99908.1 - 0.03 14.4 10.2 8.6 6.5 0.1 4.7 4 0 0 4 4 4 0 Fis1 C-terminal tetratricopeptide repeat Sel1 PF08238.12 KFX99908.1 - 0.034 14.8 3.0 6.7 7.5 0.9 3.6 2 0 0 2 2 2 0 Sel1 repeat TPR_3 PF07720.12 KFX99908.1 - 0.035 14.1 4.4 0.14 12.2 0.1 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_4 PF07721.14 KFX99908.1 - 0.04 14.5 9.3 33 5.5 0.7 5.5 4 0 0 4 4 4 0 Tetratricopeptide repeat LANC_like PF05147.13 KFX99908.1 - 0.055 12.0 1.0 0.089 11.4 0.2 1.7 2 0 0 2 2 2 0 Lanthionine synthetase C-like protein TPR_6 PF13174.6 KFX99908.1 - 0.06 14.0 31.4 5.6 7.8 0.0 9.3 10 0 0 10 10 8 0 Tetratricopeptide repeat Vps5 PF09325.10 KFX99908.1 - 0.23 11.0 4.2 0.32 10.5 0.1 3.2 3 0 0 3 3 3 0 Vps5 C terminal like MCC-bdg_PDZ PF10506.9 KFX99908.1 - 0.37 10.8 5.8 1.1 9.3 0.5 3.7 4 0 0 4 4 4 0 PDZ domain of MCC-2 bdg protein for Usher syndrome ESCRT-II PF05871.12 KFX99909.1 - 2.7e-54 183.2 0.6 3.5e-54 182.8 0.6 1.1 1 0 0 1 1 1 1 ESCRT-II complex subunit RTT107_BRCT_5 PF16770.5 KFX99910.1 - 3.9e-30 103.7 0.0 3e-26 91.2 0.0 4.0 4 1 0 4 4 4 2 Regulator of Ty1 transposition protein 107 BRCT domain PTCB-BRCT PF12738.7 KFX99910.1 - 1.9e-29 101.4 0.3 3.5e-18 65.3 0.1 4.5 4 0 0 4 4 4 3 twin BRCT domain BRCT_2 PF16589.5 KFX99910.1 - 1.2e-27 96.1 0.0 2e-05 24.9 0.0 6.3 6 0 0 6 6 6 5 BRCT domain, a BRCA1 C-terminus domain BRCT PF00533.26 KFX99910.1 - 1.7e-27 95.6 0.0 8.9e-09 35.6 0.0 6.3 6 0 0 6 6 6 5 BRCA1 C Terminus (BRCT) domain LIG3_BRCT PF16759.5 KFX99910.1 - 5.1e-13 49.1 0.2 5.4e-05 23.4 0.0 3.6 3 0 0 3 3 3 3 DNA ligase 3 BRCT domain BRCT_3 PF18428.1 KFX99910.1 - 0.0023 18.0 0.0 8.5 6.5 0.0 3.8 3 0 0 3 3 3 2 BRCA1 C Terminus (BRCT) domain Ank_2 PF12796.7 KFX99937.1 - 4.1e-67 222.8 31.9 6.2e-12 46.0 2.3 11.3 5 3 2 10 10 10 9 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KFX99937.1 - 8e-60 198.5 25.0 2.6e-07 31.0 0.1 16.4 6 5 11 18 18 18 13 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFX99937.1 - 1.9e-44 144.5 33.1 0.0029 18.0 0.0 20.9 20 1 0 20 20 20 8 Ankyrin repeat Ank PF00023.30 KFX99937.1 - 2.5e-43 144.7 56.9 0.001 19.4 0.2 19.8 20 0 0 20 20 20 13 Ankyrin repeat Ank_5 PF13857.6 KFX99937.1 - 2.3e-28 97.9 30.3 1.9e-05 24.8 0.1 11.6 7 3 7 14 14 14 9 Ankyrin repeats (many copies) NACHT PF05729.12 KFX99937.1 - 2.8e-10 40.4 0.0 9.2e-10 38.7 0.0 1.9 2 0 0 2 2 2 1 NACHT domain AAA_16 PF13191.6 KFX99937.1 - 0.00056 20.3 0.0 0.0019 18.6 0.0 1.9 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 KFX99937.1 - 0.00097 19.4 0.0 0.0029 17.9 0.0 1.8 1 0 0 1 1 1 1 AAA domain Cauli_DNA-bind PF03310.13 KFX99937.1 - 0.025 14.6 2.1 0.028 14.5 0.3 2.0 2 0 0 2 2 1 0 Caulimovirus DNA-binding protein Helo_like_N PF17111.5 KFX99937.1 - 0.034 13.5 0.7 1.4 8.3 0.3 2.4 1 1 1 2 2 2 0 Fungal N-terminal domain of STAND proteins RNA_helicase PF00910.22 KFX99937.1 - 0.068 13.6 0.1 0.25 11.8 0.0 2.0 2 0 0 2 2 2 0 RNA helicase NB-ARC PF00931.22 KFX99937.1 - 0.11 11.6 0.0 0.28 10.3 0.0 1.6 1 0 0 1 1 1 0 NB-ARC domain DUF1843 PF08898.10 KFX99937.1 - 0.99 9.9 4.7 65 4.1 0.0 5.5 6 0 0 6 6 5 0 Domain of unknown function (DUF1843) HdeA PF06411.11 KFX99938.1 - 0.066 13.4 0.0 0.098 12.9 0.0 1.3 1 0 0 1 1 1 0 HdeA/HdeB family Sugar_tr PF00083.24 KFX99939.1 - 1e-77 262.0 23.9 1.2e-77 261.7 23.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KFX99939.1 - 8.4e-24 84.1 44.1 2.3e-20 72.8 20.9 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 KFX99939.1 - 0.013 14.1 26.9 0.012 14.2 7.4 3.0 2 1 1 3 3 3 0 MFS/sugar transport protein YMF19 PF02326.15 KFX99939.1 - 0.029 15.1 1.3 1.6 9.6 0.0 2.7 2 0 0 2 2 2 0 Plant ATP synthase F0 Pam17 PF08566.10 KFX99939.1 - 0.23 11.3 1.9 0.2 11.5 0.2 1.8 2 0 0 2 2 2 0 Mitochondrial import protein Pam17 DUF5542 PF17696.1 KFX99939.1 - 1.3 9.2 3.3 3 8.0 3.3 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5542) Glyco_hydro_1 PF00232.18 KFX99940.1 - 2.3e-150 501.0 0.6 2.9e-150 500.7 0.6 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 1 Fungal_trans PF04082.18 KFX99941.1 - 2.2e-12 46.6 0.2 5.4e-12 45.3 0.2 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KFX99941.1 - 3.3e-11 43.1 4.8 5.9e-11 42.3 4.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF2656 PF10847.8 KFX99941.1 - 0.15 12.1 0.0 0.28 11.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2656) RPN6_N PF18055.1 KFX99942.1 - 0.13 12.7 0.1 0.32 11.4 0.1 1.6 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN6 N-terminal domain Pantoate_ligase PF02569.15 KFX99942.1 - 0.32 10.2 1.7 0.85 8.8 0.1 2.1 1 1 1 2 2 2 0 Pantoate-beta-alanine ligase FliS PF02561.14 KFX99942.1 - 1.4 9.2 3.9 19 5.5 0.0 3.9 3 1 1 4 4 4 0 Flagellar protein FliS AAA PF00004.29 KFX99943.1 - 2.9e-17 63.3 0.0 8.2e-17 61.9 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KFX99943.1 - 0.0032 17.8 0.2 0.015 15.5 0.1 2.2 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KFX99943.1 - 0.0055 17.1 0.0 0.013 15.9 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.14 KFX99943.1 - 0.024 14.6 0.0 0.062 13.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.26 KFX99943.1 - 0.11 12.1 0.0 0.23 11.1 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain Torsin PF06309.11 KFX99943.1 - 0.15 12.1 0.0 0.35 11.0 0.0 1.5 1 0 0 1 1 1 0 Torsin AAA_19 PF13245.6 KFX99943.1 - 0.16 12.3 1.0 0.32 11.3 0.4 1.8 2 0 0 2 2 2 0 AAA domain Nepo_coat_N PF03689.15 KFX99944.1 - 0.2 11.6 0.1 0.5 10.3 0.0 1.6 2 0 0 2 2 2 0 Nepovirus coat protein, N-terminal domain RRM_1 PF00076.22 KFX99945.1 - 6.9e-13 48.2 1.2 6.6e-05 22.7 0.0 3.6 4 0 0 4 4 4 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) G-patch PF01585.23 KFX99945.1 - 2.8e-10 39.9 2.6 6.8e-10 38.7 2.6 1.7 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.7 KFX99945.1 - 1.6e-06 28.1 1.1 4.4e-06 26.7 1.1 1.8 1 0 0 1 1 1 1 G-patch domain zf-RanBP PF00641.18 KFX99945.1 - 0.00058 19.1 0.5 0.0012 18.1 0.5 1.5 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others MT0933_antitox PF14013.6 KFX99945.1 - 0.0079 16.5 1.0 0.034 14.5 1.0 2.1 1 1 0 1 1 1 1 MT0933-like antitoxin protein RED_N PF07808.13 KFX99945.1 - 0.026 14.1 0.7 0.026 14.1 0.7 1.9 3 0 0 3 3 3 0 RED-like protein N-terminal region zf-C2H2_jaz PF12171.8 KFX99945.1 - 0.041 14.2 0.4 0.11 12.9 0.4 1.7 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding P21-Arc PF04062.14 KFX99952.1 - 1.4e-58 197.8 0.0 2.8e-58 196.8 0.0 1.5 1 0 0 1 1 1 1 ARP2/3 complex ARPC3 (21 kDa) subunit Myb_DNA-binding PF00249.31 KFX99952.1 - 9.1e-09 35.4 0.1 0.00024 21.2 0.0 2.6 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KFX99952.1 - 0.076 13.3 4.4 5.8 7.2 0.5 3.1 3 0 0 3 3 3 0 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 KFX99952.1 - 0.15 12.0 0.0 0.15 12.0 0.0 2.4 2 0 0 2 2 2 0 Myb DNA-binding like DS PF01916.17 KFX99953.1 - 5.9e-132 439.2 0.1 7e-132 439.0 0.1 1.0 1 0 0 1 1 1 1 Deoxyhypusine synthase Cation_ATPase_C PF00689.21 KFX99954.1 - 2e-43 148.2 6.0 2e-43 148.2 6.0 2.6 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 KFX99954.1 - 3.9e-33 114.5 1.7 3.9e-33 114.5 1.7 2.7 3 0 0 3 3 3 1 E1-E2 ATPase Hydrolase PF00702.26 KFX99954.1 - 1.2e-19 71.5 1.3 1e-18 68.4 1.0 2.5 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 KFX99954.1 - 1.7e-19 69.7 0.0 3.2e-19 68.8 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 KFX99954.1 - 3.8e-10 39.3 2.1 1.5e-08 34.2 0.0 3.5 3 0 0 3 3 3 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 KFX99954.1 - 0.0017 18.2 0.3 0.013 15.2 0.2 2.1 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 KFX99954.1 - 0.0097 16.3 0.0 0.025 15.0 0.0 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase LptF_LptG PF03739.14 KFX99954.1 - 0.029 13.2 2.9 0.076 11.9 2.9 1.6 1 0 0 1 1 1 0 Lipopolysaccharide export system permease LptF/LptG DUF21 PF01595.20 KFX99955.1 - 4.1e-31 108.0 1.6 7.5e-31 107.2 0.7 1.7 2 0 0 2 2 2 1 Cyclin M transmembrane N-terminal domain CBS PF00571.28 KFX99955.1 - 3.2e-07 30.7 0.1 1.9e-05 25.0 0.1 2.9 3 0 0 3 3 3 1 CBS domain BtrH_N PF14399.6 KFX99955.1 - 0.081 13.2 0.1 0.17 12.1 0.1 1.6 1 1 0 1 1 1 0 Butirosin biosynthesis protein H, N-terminal SieB PF14163.6 KFX99955.1 - 0.48 9.9 1.8 5.8 6.4 0.6 2.3 2 0 0 2 2 2 0 Super-infection exclusion protein B Cation_ATPase_C PF00689.21 KFX99956.1 - 5.8e-40 136.9 4.5 5.8e-40 136.9 4.5 2.2 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 KFX99956.1 - 8.6e-25 88.3 0.0 1.7e-14 54.6 0.0 2.8 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 KFX99956.1 - 1e-21 76.8 0.0 2e-21 75.9 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) E1-E2_ATPase PF00122.20 KFX99956.1 - 3.1e-15 56.2 5.9 3.1e-15 56.2 5.9 2.5 2 0 0 2 2 2 1 E1-E2 ATPase HAD PF12710.7 KFX99956.1 - 0.00048 20.6 0.1 0.15 12.5 0.0 3.0 3 1 0 3 3 3 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 KFX99956.1 - 0.00049 19.9 0.4 0.0012 18.6 0.2 1.7 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase LptF_LptG PF03739.14 KFX99956.1 - 0.086 11.7 4.1 0.21 10.4 4.1 1.6 1 0 0 1 1 1 0 Lipopolysaccharide export system permease LptF/LptG Nucleos_tra2_N PF01773.20 KFX99956.1 - 0.19 12.3 1.8 5.6 7.6 0.1 2.8 2 0 0 2 2 2 0 Na+ dependent nucleoside transporter N-terminus DctQ PF04290.12 KFX99956.1 - 9 6.2 16.1 0.094 12.6 4.3 3.1 3 0 0 3 3 3 0 Tripartite ATP-independent periplasmic transporters, DctQ component TFIIA_gamma_N PF02268.16 KFX99957.1 - 9.6e-24 83.1 0.1 1.3e-23 82.7 0.1 1.2 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit, helical domain TFIIA_gamma_C PF02751.14 KFX99957.1 - 4.2e-21 74.8 1.9 7.5e-21 74.0 1.9 1.4 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit ATP-synt_C PF00137.21 KFX99958.1 - 3.2e-25 88.3 33.4 1.1e-15 57.7 11.4 2.8 3 0 0 3 3 3 2 ATP synthase subunit C SLATT_5 PF18160.1 KFX99958.1 - 0.062 12.6 2.3 0.1 11.9 0.1 2.0 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain family 5 Oxidored_q2 PF00420.24 KFX99958.1 - 7.4 6.3 9.5 1.7 8.3 1.8 3.2 2 1 1 3 3 3 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L LRR_9 PF14580.6 KFX99959.1 - 3.9e-58 195.8 0.6 6.4e-58 195.1 0.1 1.6 2 0 0 2 2 2 1 Leucine-rich repeat LRR_8 PF13855.6 KFX99959.1 - 3.8e-09 36.2 1.5 5e-09 35.8 0.3 1.8 2 0 0 2 2 2 1 Leucine rich repeat LRR_4 PF12799.7 KFX99959.1 - 2.4e-07 31.0 7.1 0.00037 20.8 1.3 3.2 2 1 1 3 3 3 2 Leucine Rich repeats (2 copies) DUF4349 PF14257.6 KFX99959.1 - 0.015 14.7 0.9 0.028 13.9 0.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4349) LRR_6 PF13516.6 KFX99959.1 - 0.034 14.2 3.2 4.4 7.6 0.2 4.1 4 0 0 4 4 4 0 Leucine Rich repeat Gal11_ABD1 PF18535.1 KFX99959.1 - 0.13 12.4 0.2 0.26 11.4 0.2 1.5 1 0 0 1 1 1 0 Gal11 activator-binding domain (ABD1) DAPG_hydrolase PF18089.1 KFX99959.1 - 0.22 11.0 0.0 0.32 10.5 0.0 1.2 1 0 0 1 1 1 0 DAPG hydrolase PhiG domain Nup88 PF10168.9 KFX99959.1 - 0.25 9.1 2.5 0.56 7.9 0.6 1.9 1 1 1 2 2 2 0 Nuclear pore component AMP-binding PF00501.28 KFX99960.1 - 3.2e-26 91.9 0.0 5.3e-26 91.2 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme Pkinase PF00069.25 KFX99961.1 - 3.3e-23 82.4 0.0 5.6e-23 81.7 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain HEAT PF02985.22 KFX99961.1 - 2.7e-12 45.8 1.4 0.026 14.7 0.0 6.3 6 0 0 6 6 6 3 HEAT repeat WD40 PF00400.32 KFX99961.1 - 3.2e-08 34.1 10.9 5.2e-05 23.9 0.0 5.9 6 0 0 6 6 6 2 WD domain, G-beta repeat HEAT_EZ PF13513.6 KFX99961.1 - 1.3e-06 28.8 0.3 0.0089 16.5 0.4 4.3 5 0 0 5 5 5 1 HEAT-like repeat HEAT_2 PF13646.6 KFX99961.1 - 1.3e-05 25.5 0.1 0.6 10.5 0.2 4.0 3 1 0 4 4 4 2 HEAT repeats Pkinase_Tyr PF07714.17 KFX99961.1 - 2.1e-05 24.0 0.0 3.4e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KFX99961.1 - 0.0031 16.9 0.0 0.005 16.2 0.0 1.3 1 0 0 1 1 1 1 Kinase-like RTP1_C1 PF10363.9 KFX99961.1 - 0.0067 16.6 0.1 1.5 9.1 0.1 2.5 2 0 0 2 2 2 1 Required for nuclear transport of RNA pol II C-terminus 1 N_formyltrans_C PF18216.1 KFX99961.1 - 0.072 12.8 0.0 0.17 11.6 0.0 1.6 1 0 0 1 1 1 0 N-formyltransferase dimerization C-terminal domain Glyco_transf_90 PF05686.12 KFX99963.1 - 1.5e-14 53.8 3.7 2.2e-11 43.3 1.0 3.8 2 1 0 2 2 2 2 Glycosyl transferase family 90 Get5_C PF18514.1 KFX99963.1 - 0.016 14.9 0.0 0.047 13.4 0.0 1.8 1 0 0 1 1 1 0 Get5 C-terminal domain Ribosomal_L27A PF00828.19 KFX99964.1 - 1.3e-29 103.4 1.4 2.1e-29 102.8 1.4 1.3 1 0 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A 4HBT_3 PF13622.6 KFX99965.1 - 4.5e-27 95.9 0.1 5.8e-27 95.5 0.1 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily Acyl_CoA_thio PF02551.15 KFX99965.1 - 1e-08 35.1 0.0 6.2e-05 22.8 0.0 2.7 2 1 0 2 2 2 2 Acyl-CoA thioesterase PX PF00787.24 KFX99966.1 - 1.1e-17 64.1 0.2 2.4e-17 63.0 0.2 1.6 1 0 0 1 1 1 1 PX domain SnoaL PF07366.12 KFX99966.1 - 1e-16 60.9 0.0 3.1e-16 59.3 0.0 1.8 1 0 0 1 1 1 1 SnoaL-like polyketide cyclase SnoaL_2 PF12680.7 KFX99966.1 - 9.5e-09 35.8 0.1 2.4e-08 34.5 0.1 1.7 1 0 0 1 1 1 1 SnoaL-like domain Tmemb_cc2 PF10267.9 KFX99966.1 - 0.053 12.7 0.7 0.083 12.0 0.7 1.2 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein Prefoldin_3 PF13758.6 KFX99966.1 - 0.087 12.9 0.2 0.087 12.9 0.2 2.3 2 0 0 2 2 2 0 Prefoldin subunit HflK_N PF12221.8 KFX99966.1 - 6.6 6.8 6.1 14 5.7 1.0 3.6 3 0 0 3 3 3 0 Bacterial membrane protein N terminal Mtf2_C PF14061.6 KFX99967.1 - 0.028 14.6 2.4 0.8 9.9 0.0 2.7 3 0 0 3 3 3 0 Polycomb-like MTF2 factor 2 DYW_deaminase PF14432.6 KFX99967.1 - 0.087 12.7 0.1 0.23 11.3 0.0 1.7 2 0 0 2 2 2 0 DYW family of nucleic acid deaminases Chromo PF00385.24 KFX99967.1 - 0.32 10.9 8.7 1.3 9.0 0.6 3.3 3 1 0 3 3 3 0 Chromo (CHRromatin Organisation MOdifier) domain Ribosomal_S19e PF01090.19 KFX99968.1 - 2.4e-58 195.7 0.2 2.8e-58 195.5 0.2 1.0 1 0 0 1 1 1 1 Ribosomal protein S19e Abhydrolase_6 PF12697.7 KFX99969.1 - 1.5e-20 74.8 0.1 3.6e-20 73.5 0.1 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KFX99969.1 - 3.5e-17 62.9 0.0 1.8e-16 60.5 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KFX99969.1 - 3.5e-13 49.4 0.0 5.1e-12 45.6 0.0 2.6 2 1 0 2 2 2 1 Serine aminopeptidase, S33 DSPc PF00782.20 KFX99969.1 - 6.6e-11 42.2 0.0 1.7e-10 40.8 0.0 1.7 1 1 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Thioesterase PF00975.20 KFX99969.1 - 1.8e-07 31.5 0.1 8.4e-07 29.3 0.0 2.0 2 0 0 2 2 2 1 Thioesterase domain PGAP1 PF07819.13 KFX99969.1 - 8.7e-05 22.3 0.0 0.0021 17.8 0.0 2.3 2 0 0 2 2 2 1 PGAP1-like protein PTPlike_phytase PF14566.6 KFX99969.1 - 0.0001 22.5 0.0 0.00016 21.9 0.0 1.3 1 0 0 1 1 1 1 Inositol hexakisphosphate Esterase PF00756.20 KFX99969.1 - 0.0021 17.8 0.0 0.0041 16.8 0.0 1.4 1 0 0 1 1 1 1 Putative esterase Y_phosphatase PF00102.27 KFX99969.1 - 0.0022 17.6 0.0 0.0042 16.7 0.0 1.4 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Lipase_3 PF01764.25 KFX99969.1 - 0.0025 17.7 0.0 0.0059 16.5 0.0 1.6 1 0 0 1 1 1 1 Lipase (class 3) LCAT PF02450.15 KFX99969.1 - 0.0086 15.3 0.0 0.014 14.6 0.0 1.2 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase Ser_hydrolase PF06821.13 KFX99969.1 - 0.058 13.2 0.0 0.15 12.0 0.0 1.6 1 0 0 1 1 1 0 Serine hydrolase Abhydrolase_2 PF02230.16 KFX99969.1 - 0.058 13.2 0.0 3.5 7.4 0.0 2.2 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase VirJ PF06057.11 KFX99969.1 - 0.14 12.0 0.0 0.33 10.8 0.0 1.5 1 0 0 1 1 1 0 Bacterial virulence protein (VirJ) DUF676 PF05057.14 KFX99969.1 - 0.15 11.6 0.0 0.27 10.7 0.0 1.4 1 0 0 1 1 1 0 Putative serine esterase (DUF676) LIDHydrolase PF10230.9 KFX99969.1 - 0.16 11.5 0.0 0.27 10.8 0.0 1.2 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase DUF900 PF05990.12 KFX99969.1 - 0.16 11.4 0.0 0.28 10.7 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) Chlorophyllase2 PF12740.7 KFX99969.1 - 0.16 10.8 0.0 0.31 9.9 0.0 1.4 1 0 0 1 1 1 0 Chlorophyllase enzyme DLH PF01738.18 KFX99969.1 - 0.22 11.1 0.0 3.2 7.2 0.0 2.2 2 0 0 2 2 2 0 Dienelactone hydrolase family UQ_con PF00179.26 KFX99970.1 - 2.7e-19 69.2 0.0 4.6e-19 68.4 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme B-block_TFIIIC PF04182.12 KFX99972.1 - 1.6e-13 50.6 0.0 4.1e-13 49.3 0.0 1.8 1 0 0 1 1 1 1 B-block binding subunit of TFIIIC MarR_2 PF12802.7 KFX99972.1 - 0.0078 16.1 0.0 0.059 13.3 0.0 2.5 2 0 0 2 2 2 1 MarR family RNA_pol_Rpc34 PF05158.12 KFX99972.1 - 0.081 12.3 0.0 0.23 10.8 0.0 1.7 2 0 0 2 2 2 0 RNA polymerase Rpc34 subunit CAF1C_H4-bd PF12265.8 KFX99973.1 - 2.5e-14 53.3 0.1 1.2e-13 51.1 0.0 2.3 3 0 0 3 3 3 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex WD40 PF00400.32 KFX99973.1 - 7.9e-13 48.7 7.7 3.4e-06 27.7 0.1 3.8 4 0 0 4 4 4 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFX99973.1 - 5.8e-07 29.7 1.2 0.00057 20.1 0.2 3.2 2 1 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KFX99973.1 - 0.025 13.2 1.4 0.039 12.6 0.6 1.7 1 1 1 2 2 2 0 Nucleoporin Nup120/160 Adenylsucc_synt PF00709.21 KFX99977.1 - 1.2e-170 568.1 0.1 1.3e-170 567.9 0.1 1.0 1 0 0 1 1 1 1 Adenylosuccinate synthetase DUF5527 PF17665.1 KFX99978.1 - 0.0078 15.7 2.5 0.01 15.4 2.5 1.2 1 0 0 1 1 1 1 Family of unknown function (DUF5527) Mak10 PF04112.13 KFX99989.1 - 4.9e-59 198.6 0.3 8.4e-59 197.8 0.3 1.4 1 0 0 1 1 1 1 Mak10 subunit, NatC N(alpha)-terminal acetyltransferase ATP-synt_Eps PF04627.13 KFX99990.1 - 3.1e-21 75.1 3.3 3.1e-21 75.1 3.3 2.2 2 0 0 2 2 2 1 Mitochondrial ATP synthase epsilon chain Peptidase_M16 PF00675.20 KFX99990.1 - 3.2e-16 59.6 0.4 8.7e-16 58.2 0.1 1.8 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 KFX99990.1 - 1.3e-12 48.1 0.0 2.7e-12 47.1 0.0 1.5 1 0 0 1 1 1 1 Peptidase M16 inactive domain RNA_pol_Rpc82 PF05645.13 KFX99991.1 - 3.9e-49 167.7 0.3 4.5e-46 157.7 0.0 3.1 2 1 1 3 3 3 2 RNA polymerase III subunit RPC82 HTH_9 PF08221.11 KFX99991.1 - 7.6e-18 64.4 2.2 3.7e-15 55.8 0.3 3.6 3 0 0 3 3 3 1 RNA polymerase III subunit RPC82 helix-turn-helix domain TFIIE_alpha PF02002.17 KFX99991.1 - 2.5e-10 40.1 0.5 1.8e-05 24.6 0.1 2.9 2 0 0 2 2 2 2 TFIIE alpha subunit DUF977 PF06163.11 KFX99991.1 - 0.1 12.6 3.1 1 9.3 0.2 2.4 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF977) Rio2_N PF09202.11 KFX99991.1 - 0.15 12.3 0.6 75 3.6 0.1 3.4 3 0 0 3 3 3 0 Rio2, N-terminal Mito_carr PF00153.27 KFX99992.1 - 7.9e-30 102.6 1.7 5.3e-14 51.9 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein NCE101 PF11654.8 KFX99993.1 - 1.3e-09 37.6 0.0 1.8e-09 37.1 0.0 1.2 1 0 0 1 1 1 1 Non-classical export protein 1 Acyl-CoA_dh_1 PF00441.24 KFY00015.1 - 4.9e-33 114.5 0.9 7e-33 114.0 0.9 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 KFY00015.1 - 4.6e-22 78.0 0.1 8.8e-22 77.1 0.1 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 KFY00015.1 - 3.1e-14 53.6 0.1 2.8e-13 50.5 0.0 2.5 2 1 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 KFY00015.1 - 1.6e-05 25.2 0.1 2.6e-05 24.5 0.1 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Ras PF00071.22 KFY00016.1 - 1.5e-28 99.4 0.0 2.8e-28 98.6 0.0 1.4 1 1 0 1 1 1 1 Ras family Roc PF08477.13 KFY00016.1 - 0.00044 20.4 0.0 0.0069 16.6 0.0 2.2 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase FeoB_N PF02421.18 KFY00016.1 - 0.045 13.3 0.0 2.1 7.9 0.0 2.2 2 0 0 2 2 2 0 Ferrous iron transport protein B PBP PF01161.20 KFY00022.1 - 6.1e-10 39.5 0.0 1.2e-09 38.6 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein DnaJ_C PF01556.18 KFY00024.1 - 6e-37 127.0 0.0 8.9e-37 126.4 0.0 1.3 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 KFY00024.1 - 1.9e-22 79.1 1.2 3.9e-22 78.1 1.2 1.5 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 KFY00024.1 - 2.6e-09 37.3 20.5 5.8e-09 36.2 20.5 1.7 1 0 0 1 1 1 1 DnaJ central domain SAP30_Sin3_bdg PF13867.6 KFY00024.1 - 1.2e-08 35.1 0.1 4.7e-08 33.2 0.1 1.9 2 0 0 2 2 2 1 Sin3 binding region of histone deacetylase complex subunit SAP30 DAO PF01266.24 KFY00049.1 - 3e-09 36.9 0.0 3.2e-09 36.8 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.17 KFY00049.1 - 2.4e-05 23.7 0.1 3e-05 23.4 0.1 1.1 1 0 0 1 1 1 1 Thi4 family NAD_binding_8 PF13450.6 KFY00049.1 - 2.9e-05 24.2 0.1 5.3e-05 23.4 0.1 1.4 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 KFY00049.1 - 0.00071 18.8 0.0 0.00071 18.8 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 KFY00049.1 - 0.0041 16.4 0.0 0.0041 16.4 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 KFY00049.1 - 0.021 14.1 0.1 0.025 13.8 0.1 1.1 1 0 0 1 1 1 0 FAD binding domain Pyr_redox PF00070.27 KFY00049.1 - 0.025 15.1 0.0 0.035 14.7 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 KFY00049.1 - 0.063 12.1 0.1 0.075 11.9 0.1 1.1 1 0 0 1 1 1 0 Tryptophan halogenase NAD_binding_9 PF13454.6 KFY00049.1 - 0.082 12.9 0.0 0.082 12.9 0.0 1.2 1 0 0 1 1 1 0 FAD-NAD(P)-binding GMC_oxred_N PF00732.19 KFY00049.1 - 0.12 11.8 0.0 0.13 11.7 0.0 1.1 1 0 0 1 1 1 0 GMC oxidoreductase Pyr_redox_3 PF13738.6 KFY00049.1 - 0.15 11.2 0.0 0.17 11.1 0.0 1.1 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.6 KFY00049.1 - 0.22 12.0 0.0 0.23 11.9 0.0 1.1 1 0 0 1 1 1 0 Putative NAD(P)-binding HI0933_like PF03486.14 KFY00049.1 - 0.28 9.8 0.2 0.42 9.3 0.2 1.2 1 0 0 1 1 1 0 HI0933-like protein OTU PF02338.19 KFY00050.1 - 4.3e-10 40.2 0.0 1.5e-09 38.4 0.0 1.8 1 1 0 1 1 1 1 OTU-like cysteine protease CUE PF02845.16 KFY00050.1 - 0.00077 19.1 0.0 0.0014 18.3 0.0 1.4 1 0 0 1 1 1 1 CUE domain UBA_4 PF14555.6 KFY00050.1 - 0.0015 18.3 0.0 0.0031 17.3 0.0 1.5 1 0 0 1 1 1 1 UBA-like domain Peptidase_C65 PF10275.9 KFY00050.1 - 0.17 11.3 0.0 5.2 6.4 0.0 2.2 2 0 0 2 2 2 0 Peptidase C65 Otubain Thioredoxin PF00085.20 KFY00051.1 - 2e-28 98.4 0.1 2.5e-28 98.1 0.1 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 KFY00051.1 - 1.5e-06 28.6 0.0 2.9e-06 27.7 0.0 1.5 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.6 KFY00051.1 - 9.6e-06 25.8 0.0 6.1e-05 23.3 0.0 2.0 1 1 0 1 1 1 1 Thioredoxin-like OST3_OST6 PF04756.13 KFY00051.1 - 0.00011 21.7 0.0 0.00011 21.6 0.0 1.1 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin_9 PF14595.6 KFY00051.1 - 0.00019 21.2 0.0 0.00024 20.9 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin AhpC-TSA PF00578.21 KFY00051.1 - 0.00061 19.7 0.0 0.00072 19.5 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 KFY00051.1 - 0.0033 17.2 0.1 0.042 13.6 0.1 2.0 1 1 1 2 2 2 1 Redoxin Glutaredoxin PF00462.24 KFY00051.1 - 0.0081 16.4 0.2 0.1 12.8 0.1 2.2 1 1 1 2 2 2 1 Glutaredoxin Phosducin PF02114.16 KFY00051.1 - 0.017 14.1 0.0 0.02 13.8 0.0 1.0 1 0 0 1 1 1 0 Phosducin Thioredoxin_7 PF13899.6 KFY00051.1 - 0.044 14.0 0.1 0.074 13.3 0.1 1.5 1 1 0 1 1 1 0 Thioredoxin-like TraF PF13728.6 KFY00051.1 - 0.058 13.2 0.0 0.07 12.9 0.0 1.1 1 0 0 1 1 1 0 F plasmid transfer operon protein Thioredox_DsbH PF03190.15 KFY00051.1 - 0.09 12.7 0.1 0.12 12.3 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function, DUF255 HyaE PF07449.11 KFY00051.1 - 0.099 12.6 0.0 0.25 11.3 0.0 1.6 2 0 0 2 2 2 0 Hydrogenase-1 expression protein HyaE PCYCGC PF13798.6 KFY00051.1 - 0.12 12.2 0.0 0.15 11.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function with PCYCGC motif Aspzincin_M35 PF14521.6 KFY00052.1 - 0.098 13.2 0.2 0.18 12.3 0.2 1.4 1 0 0 1 1 1 0 Lysine-specific metallo-endopeptidase Mannosyl_trans2 PF04188.13 KFY00057.1 - 2.6e-55 188.5 3.8 3.3e-55 188.2 3.8 1.1 1 0 0 1 1 1 1 Mannosyltransferase (PIG-V) Colipase_C PF02740.14 KFY00061.1 - 7.8e-05 22.8 0.6 7.8e-05 22.8 0.6 2.5 3 0 0 3 3 3 1 Colipase, C-terminal domain Prokineticin PF06607.11 KFY00061.1 - 0.03 14.6 5.8 0.038 14.3 5.8 1.1 1 0 0 1 1 1 0 Prokineticin NACHT PF05729.12 KFY00062.1 - 9.1e-09 35.4 0.1 2.9e-08 33.8 0.1 1.9 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 KFY00062.1 - 1.7e-07 31.8 0.2 5.7e-07 30.1 0.2 2.0 1 1 0 1 1 1 1 AAA ATPase domain AAA_14 PF13173.6 KFY00062.1 - 1.6e-06 28.2 0.0 8.4e-05 22.6 0.0 2.9 1 1 0 1 1 1 1 AAA domain Ank_2 PF12796.7 KFY00062.1 - 2.5e-05 24.8 0.0 0.0018 18.8 0.0 3.6 4 0 0 4 4 4 1 Ankyrin repeats (3 copies) NB-ARC PF00931.22 KFY00062.1 - 0.00019 20.7 0.0 0.00064 19.0 0.0 1.8 2 0 0 2 2 2 1 NB-ARC domain AAA_22 PF13401.6 KFY00062.1 - 0.0016 18.7 0.0 0.0043 17.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain DAP3 PF10236.9 KFY00062.1 - 0.014 14.6 0.1 0.031 13.4 0.1 1.5 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 AAA_7 PF12775.7 KFY00062.1 - 0.05 13.1 0.3 0.2 11.1 0.0 2.1 3 0 0 3 3 3 0 P-loop containing dynein motor region AAA_29 PF13555.6 KFY00062.1 - 0.051 13.3 0.4 0.11 12.2 0.4 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_25 PF13481.6 KFY00062.1 - 0.062 12.9 0.2 0.16 11.5 0.2 1.6 1 0 0 1 1 1 0 AAA domain PSRP-3_Ycf65 PF04839.13 KFY00062.1 - 0.072 13.3 0.6 3.1 8.1 0.0 2.7 2 0 0 2 2 2 0 Plastid and cyanobacterial ribosomal protein (PSRP-3 / Ycf65) AAA_30 PF13604.6 KFY00062.1 - 0.097 12.4 0.0 0.3 10.8 0.0 1.8 2 0 0 2 2 2 0 AAA domain G-alpha PF00503.20 KFY00062.1 - 0.12 11.5 0.0 0.23 10.6 0.0 1.4 1 0 0 1 1 1 0 G-protein alpha subunit PIF1 PF05970.14 KFY00062.1 - 0.15 11.2 0.0 18 4.4 0.0 2.3 2 0 0 2 2 2 0 PIF1-like helicase RsgA_GTPase PF03193.16 KFY00062.1 - 0.16 11.9 0.2 0.43 10.5 0.2 1.7 1 0 0 1 1 1 0 RsgA GTPase Cupin_2 PF07883.11 KFY00064.1 - 0.00048 19.8 0.0 0.0025 17.5 0.0 2.1 1 1 0 1 1 1 1 Cupin domain Rep_fac-A_3 PF08661.11 KFY00065.1 - 7.6e-25 87.3 0.0 8.3e-25 87.2 0.0 1.0 1 0 0 1 1 1 1 Replication factor A protein 3 tRNA-synt_2 PF00152.20 KFY00066.1 - 2.8e-79 266.5 0.4 4.1e-79 265.9 0.4 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 KFY00066.1 - 9e-10 38.4 0.0 2.2e-09 37.2 0.0 1.7 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 KFY00066.1 - 2.4e-06 27.2 0.1 0.0045 16.5 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) COX15-CtaA PF02628.15 KFY00067.1 - 9.3e-24 84.1 0.2 1.1e-23 83.8 0.2 1.1 1 0 0 1 1 1 1 Cytochrome oxidase assembly protein NMO PF03060.15 KFY00073.1 - 1.5e-12 47.6 0.0 1.6e-12 47.5 0.0 1.0 1 0 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.25 KFY00073.1 - 4.2e-06 26.0 0.0 4.2e-06 26.0 0.0 1.0 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain TPP_enzyme_N PF02776.18 KFY00074.1 - 5.6e-30 104.2 0.1 9.3e-30 103.5 0.1 1.3 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.22 KFY00074.1 - 2.1e-16 59.9 0.0 4.7e-16 58.8 0.0 1.6 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.21 KFY00074.1 - 1.2e-12 47.8 0.1 3.8e-12 46.2 0.0 1.8 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Amidohydro_2 PF04909.14 KFY00075.1 - 2.9e-40 138.9 0.3 3.7e-40 138.5 0.3 1.2 1 0 0 1 1 1 1 Amidohydrolase AMP-binding PF00501.28 KFY00076.1 - 2.3e-92 309.8 0.0 3.1e-92 309.4 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KFY00076.1 - 8.2e-13 49.1 0.0 1.6e-12 48.2 0.0 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Zn_clus PF00172.18 KFY00076.1 - 4.9e-05 23.4 9.1 8.2e-05 22.7 9.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KFY00076.1 - 0.0002 20.5 0.0 0.00068 18.7 0.0 1.7 1 1 1 2 2 2 1 Fungal specific transcription factor domain ketoacyl-synt PF00109.26 KFY00078.1 - 1.1e-69 234.9 0.0 3.4e-69 233.2 0.0 1.9 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.10 KFY00078.1 - 5.4e-60 202.4 1.1 1.5e-59 201.0 0.1 2.3 2 0 0 2 2 2 1 KR domain PS-DH PF14765.6 KFY00078.1 - 7e-53 179.8 0.0 1.2e-52 179.0 0.0 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase Acyl_transf_1 PF00698.21 KFY00078.1 - 2.9e-51 174.9 0.0 6.2e-51 173.8 0.0 1.5 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 KFY00078.1 - 1.3e-37 128.4 0.6 4e-37 126.8 0.2 2.1 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain KAsynt_C_assoc PF16197.5 KFY00078.1 - 8.4e-12 45.5 0.0 2e-11 44.3 0.0 1.7 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension adh_short PF00106.25 KFY00078.1 - 3e-08 33.4 0.0 7.8e-08 32.0 0.0 1.7 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KFY00078.1 - 8.8e-07 28.7 0.0 2.2e-06 27.4 0.0 1.6 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase PP-binding PF00550.25 KFY00078.1 - 9e-05 22.7 0.0 0.00025 21.3 0.0 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site ADH_zinc_N_2 PF13602.6 KFY00078.1 - 0.00032 21.8 0.1 0.0016 19.5 0.0 2.3 2 0 0 2 2 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 KFY00078.1 - 0.00058 19.8 0.0 0.0025 17.8 0.0 2.1 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Thiolase_N PF00108.23 KFY00078.1 - 0.046 13.1 0.0 0.12 11.7 0.0 1.6 1 0 0 1 1 1 0 Thiolase, N-terminal domain ACP_syn_III PF08545.10 KFY00078.1 - 0.047 13.6 0.9 0.5 10.2 0.0 3.0 3 0 0 3 3 3 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Zn_clus PF00172.18 KFY00079.1 - 3e-07 30.5 9.4 3e-07 30.5 9.4 1.9 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Opy2 PF09463.10 KFY00079.1 - 7.8 6.9 12.8 3.5 8.0 9.3 2.3 2 0 0 2 2 2 0 Opy2 protein EthD PF07110.11 KFY00081.1 - 1.4e-16 61.4 0.7 1.6e-16 61.2 0.7 1.1 1 0 0 1 1 1 1 EthD domain MmlI PF09448.10 KFY00081.1 - 9.5e-05 22.8 0.1 0.0002 21.8 0.1 1.6 1 1 0 1 1 1 1 Methylmuconolactone methyl-isomerase XdhC_C PF13478.6 KFY00081.1 - 0.045 14.2 0.0 0.045 14.2 0.0 1.1 1 0 0 1 1 1 0 XdhC Rossmann domain SinI PF08671.10 KFY00081.1 - 0.072 12.9 0.0 0.12 12.2 0.0 1.3 1 0 0 1 1 1 0 Anti-repressor SinI p450 PF00067.22 KFY00082.1 - 2.2e-52 178.4 0.0 2.9e-52 178.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 ADH_zinc_N PF00107.26 KFY00083.1 - 1.9e-08 34.3 0.1 4.1e-08 33.3 0.1 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KFY00083.1 - 5.3e-08 32.7 0.1 1e-07 31.8 0.1 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_N_2 PF16884.5 KFY00083.1 - 0.017 15.0 0.1 0.039 13.9 0.1 1.5 1 0 0 1 1 1 0 N-terminal domain of oxidoreductase Glyco_hydro_49 PF03718.13 KFY00083.1 - 0.12 12.3 0.0 0.22 11.5 0.0 1.4 1 0 0 1 1 1 0 Glycosyl hydrolase family 49 NAD_binding_8 PF13450.6 KFY00084.1 - 4.5e-12 46.0 0.5 1.2e-11 44.7 0.1 1.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.7 KFY00084.1 - 1.7e-09 37.6 0.0 3.8e-09 36.4 0.1 1.5 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KFY00084.1 - 1.3e-05 24.6 0.1 2.5e-05 23.7 0.1 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KFY00084.1 - 2.2e-05 23.7 1.4 3.3e-05 23.2 1.4 1.2 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 KFY00084.1 - 2.9e-05 23.0 0.7 4.4e-05 22.4 0.7 1.2 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox PF00070.27 KFY00084.1 - 3.5e-05 24.3 0.1 7.3e-05 23.2 0.1 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KFY00084.1 - 0.00018 21.2 0.3 0.00079 19.1 0.7 1.8 2 0 0 2 2 2 1 FAD dependent oxidoreductase Amino_oxidase PF01593.24 KFY00084.1 - 0.0005 19.5 0.0 0.00064 19.1 0.0 1.2 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase GIDA PF01134.22 KFY00084.1 - 0.0026 16.9 0.2 0.0036 16.4 0.2 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A Pyr_redox_3 PF13738.6 KFY00084.1 - 0.011 15.0 0.0 0.019 14.3 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 KFY00084.1 - 0.015 14.6 0.1 0.024 13.9 0.1 1.2 1 0 0 1 1 1 0 FAD binding domain AlaDh_PNT_C PF01262.21 KFY00084.1 - 0.018 14.3 0.1 0.047 13.0 0.0 1.7 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain ApbA PF02558.16 KFY00084.1 - 0.038 13.7 1.0 0.076 12.7 0.6 1.7 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA FAD_binding_3 PF01494.19 KFY00085.1 - 7.5e-18 64.9 6.4 2.6e-12 46.6 1.7 2.8 2 1 0 2 2 2 2 FAD binding domain DAO PF01266.24 KFY00085.1 - 9.8e-06 25.4 1.1 2.4e-05 24.1 0.4 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KFY00085.1 - 0.00048 20.3 0.6 0.0016 18.6 0.6 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KFY00085.1 - 0.0011 18.3 0.2 0.015 14.5 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KFY00085.1 - 0.0063 15.6 1.6 0.033 13.3 0.5 2.5 3 0 0 3 3 3 1 FAD binding domain Pyr_redox PF00070.27 KFY00085.1 - 0.033 14.7 0.5 0.071 13.7 0.5 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Transferase PF02458.15 KFY00086.1 - 1.8e-28 99.4 0.0 3.1e-28 98.6 0.0 1.3 2 0 0 2 2 2 1 Transferase family FSH1 PF03959.13 KFY00087.1 - 4.5e-27 95.1 0.0 6e-27 94.7 0.0 1.1 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_2 PF02230.16 KFY00087.1 - 0.0097 15.7 0.7 0.037 13.8 0.1 2.1 2 1 0 2 2 2 1 Phospholipase/Carboxylesterase Abhydrolase_6 PF12697.7 KFY00087.1 - 0.018 15.7 1.6 0.023 15.3 1.6 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family ketoacyl-synt PF00109.26 KFY00088.1 - 3e-74 249.8 0.1 6.7e-74 248.6 0.1 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain HTH_51 PF18558.1 KFY00088.1 - 3.1e-35 119.9 0.0 1.1e-34 118.2 0.0 2.1 1 0 0 1 1 1 1 Helix-turn-helix domain Ketoacyl-synt_C PF02801.22 KFY00088.1 - 2.4e-29 101.7 0.1 5.9e-29 100.5 0.1 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain NAD_binding_4 PF07993.12 KFY00088.1 - 2.6e-26 92.4 0.0 4.7e-26 91.5 0.0 1.5 1 0 0 1 1 1 1 Male sterility protein Acyl_transf_1 PF00698.21 KFY00088.1 - 6e-26 91.7 0.1 4.5e-24 85.5 0.0 2.3 2 0 0 2 2 2 1 Acyl transferase domain SAT PF16073.5 KFY00088.1 - 1.2e-16 61.2 4.6 8.6e-15 55.1 0.7 2.8 2 0 0 2 2 2 2 Starter unit:ACP transacylase in aflatoxin biosynthesis Methyltransf_12 PF08242.12 KFY00088.1 - 3.5e-14 53.3 0.0 1.3e-13 51.5 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KFY00088.1 - 4.6e-11 43.3 0.0 2.4e-10 41.0 0.0 2.4 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KFY00088.1 - 1.6e-10 41.4 0.0 5e-10 39.9 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain PP-binding PF00550.25 KFY00088.1 - 2.4e-10 40.6 1.0 7.8e-10 39.0 1.0 1.9 1 0 0 1 1 1 1 Phosphopantetheine attachment site Methyltransf_23 PF13489.6 KFY00088.1 - 5.9e-10 39.2 0.0 1.8e-09 37.7 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Epimerase PF01370.21 KFY00088.1 - 2.7e-09 36.8 0.0 4.9e-09 36.0 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Methyltransf_31 PF13847.6 KFY00088.1 - 9e-09 35.3 0.0 2.3e-08 33.9 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Thiolase_N PF00108.23 KFY00088.1 - 7e-07 28.9 0.1 5e-06 26.1 0.1 2.2 2 0 0 2 2 2 1 Thiolase, N-terminal domain KAsynt_C_assoc PF16197.5 KFY00088.1 - 1.5e-05 25.4 0.0 4.2e-05 24.0 0.0 1.8 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension NodS PF05401.11 KFY00088.1 - 0.00011 21.8 0.0 0.00023 20.9 0.0 1.4 1 0 0 1 1 1 1 Nodulation protein S (NodS) PS-DH PF14765.6 KFY00088.1 - 0.00017 21.0 0.0 0.00034 19.9 0.0 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase Ubie_methyltran PF01209.18 KFY00088.1 - 0.0003 20.2 0.0 0.00087 18.7 0.0 1.7 2 0 0 2 2 1 1 ubiE/COQ5 methyltransferase family Methyltransf_16 PF10294.9 KFY00088.1 - 0.00031 20.5 0.0 0.00073 19.3 0.0 1.6 1 0 0 1 1 1 1 Lysine methyltransferase KR PF08659.10 KFY00088.1 - 0.00054 19.9 0.1 0.0014 18.5 0.1 1.7 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 KFY00088.1 - 0.0017 17.6 0.0 0.01 15.0 0.0 2.0 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein GDP_Man_Dehyd PF16363.5 KFY00088.1 - 0.011 15.2 0.0 0.02 14.3 0.0 1.4 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 KFY00088.1 - 0.012 14.7 0.0 1.2 8.2 0.0 2.5 2 0 0 2 2 2 0 RmlD substrate binding domain RrnaAD PF00398.20 KFY00088.1 - 0.1 11.7 0.0 0.18 10.9 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Methyltransf_28 PF02636.17 KFY00088.1 - 0.1 12.2 0.0 0.25 11.0 0.0 1.6 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase DUF3886 PF13025.6 KFY00089.1 - 0.043 14.0 1.5 0.043 14.0 1.5 2.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3886) adh_short PF00106.25 KFY00090.1 - 4.9e-37 127.3 0.0 6.6e-37 126.9 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KFY00090.1 - 3.9e-22 79.0 0.0 5.2e-22 78.6 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KFY00090.1 - 0.00017 21.6 0.0 0.00053 20.0 0.0 1.8 1 1 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 KFY00090.1 - 0.025 13.7 0.0 0.034 13.3 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Histone PF00125.24 KFY00107.1 - 1.9e-08 34.7 2.1 0.0016 18.8 0.1 2.7 1 1 0 2 2 2 2 Core histone H2A/H2B/H3/H4 FMN_dh PF01070.18 KFY00110.1 - 2e-120 402.0 0.0 2.4e-120 401.7 0.0 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase ThiG PF05690.14 KFY00110.1 - 9e-05 21.9 0.1 0.12 11.6 0.1 2.4 2 0 0 2 2 2 2 Thiazole biosynthesis protein ThiG NMO PF03060.15 KFY00110.1 - 0.00021 20.8 1.4 0.00031 20.3 1.4 1.1 1 0 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.25 KFY00110.1 - 0.00025 20.2 3.2 0.00081 18.5 1.9 2.3 1 1 1 2 2 2 1 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.17 KFY00110.1 - 0.0004 19.6 0.3 0.00066 18.9 0.3 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase His_biosynth PF00977.21 KFY00110.1 - 0.0021 17.6 0.1 0.058 12.9 0.0 2.2 2 0 0 2 2 2 1 Histidine biosynthesis protein Methyltransf_23 PF13489.6 KFY00111.1 - 5.6e-09 36.0 0.0 2.1e-08 34.2 0.0 1.7 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 KFY00111.1 - 2.1e-08 34.8 0.0 4.6e-08 33.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KFY00111.1 - 4.9e-07 30.3 0.0 1.2e-06 29.1 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KFY00111.1 - 1.3e-06 29.1 0.0 5.2e-06 27.1 0.0 2.0 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 KFY00111.1 - 8e-06 25.7 0.0 1.3e-05 25.0 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KFY00111.1 - 0.024 14.0 0.0 0.038 13.3 0.0 1.3 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family EI24 PF07264.11 KFY00112.1 - 1e-14 55.2 1.4 1.7e-14 54.4 1.4 1.4 1 1 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) zf-RING_2 PF13639.6 KFY00113.1 - 2.5e-12 46.9 5.1 5.2e-12 45.9 5.1 1.6 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 KFY00113.1 - 7.3e-09 35.3 4.0 1.3e-08 34.5 4.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Glyco_transf_92 PF01697.27 KFY00113.1 - 9.5e-09 35.3 0.3 3.1e-08 33.6 0.3 1.8 1 1 0 1 1 1 1 Glycosyltransferase family 92 PA PF02225.22 KFY00113.1 - 1e-08 35.1 1.4 1.4e-08 34.6 0.0 2.0 2 0 0 2 2 1 1 PA domain zf-rbx1 PF12678.7 KFY00113.1 - 1.4e-08 34.9 2.0 1.4e-08 34.9 2.0 2.2 2 0 0 2 2 2 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 KFY00113.1 - 1.8e-08 34.1 2.7 3.2e-08 33.3 2.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 KFY00113.1 - 2.1e-08 33.7 2.2 2.1e-08 33.7 2.2 1.9 2 0 0 2 2 2 1 RING-like zinc finger zf-RING_5 PF14634.6 KFY00113.1 - 1.8e-06 27.8 2.0 3e-06 27.1 2.0 1.4 1 0 0 1 1 1 1 zinc-RING finger domain Glyco_tranf_2_4 PF13704.6 KFY00113.1 - 3.5e-06 27.5 0.9 8.2e-06 26.3 0.9 1.6 1 0 0 1 1 1 1 Glycosyl transferase family 2 zf-C3HC4_3 PF13920.6 KFY00113.1 - 3.1e-05 23.7 2.8 4.8e-05 23.1 2.8 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KFY00113.1 - 5.4e-05 23.1 2.0 8.8e-05 22.5 0.4 2.2 1 1 1 2 2 2 1 RING-type zinc-finger zf-ANAPC11 PF12861.7 KFY00113.1 - 0.004 17.2 0.8 0.004 17.2 0.8 2.1 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger RRP14 PF15459.6 KFY00113.1 - 0.0065 17.1 1.1 0.028 15.0 1.1 2.1 1 0 0 1 1 1 1 60S ribosome biogenesis protein Rrp14 Prok-RING_4 PF14447.6 KFY00113.1 - 0.024 14.5 2.9 0.044 13.6 2.9 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 KFY00113.1 - 0.038 14.1 2.3 0.094 12.9 2.4 1.7 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING Zn_ribbon_17 PF17120.5 KFY00113.1 - 0.092 12.4 3.0 0.2 11.3 3.0 1.4 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type ODV-E18 PF10717.9 KFY00113.1 - 0.12 12.2 0.4 1.1 9.2 0.1 2.5 2 0 0 2 2 2 0 Occlusion-derived virus envelope protein ODV-E18 FANCL_C PF11793.8 KFY00113.1 - 0.18 12.0 1.6 0.48 10.6 1.6 1.8 1 1 0 1 1 1 0 FANCL C-terminal domain zf-RING-like PF08746.11 KFY00113.1 - 0.28 11.5 3.0 0.5 10.7 3.0 1.4 1 0 0 1 1 1 0 RING-like domain zf-RING_4 PF14570.6 KFY00113.1 - 0.59 10.0 2.6 1.2 9.0 2.6 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain RINGv PF12906.7 KFY00113.1 - 0.8 9.9 3.2 1.6 8.9 3.2 1.6 1 0 0 1 1 1 0 RING-variant domain PHD PF00628.29 KFY00113.1 - 1.1 9.2 2.4 2.2 8.2 2.4 1.5 1 0 0 1 1 1 0 PHD-finger ASFV_J13L PF05568.11 KFY00113.1 - 2.6 7.8 6.3 12 5.6 6.3 2.2 1 0 0 1 1 1 0 African swine fever virus J13L protein ACPS PF01648.20 KFY00114.1 - 1.2e-07 31.9 0.1 8.6e-07 29.1 0.1 2.2 1 1 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily Glyco_hydro_61 PF03443.14 KFY00115.1 - 9e-54 182.5 0.0 1.1e-53 182.3 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 DUF4360 PF14273.6 KFY00116.1 - 2.3e-61 206.7 2.3 6.3e-61 205.3 2.3 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF4360) NmrA PF05368.13 KFY00117.1 - 4e-30 105.1 0.0 5.1e-30 104.8 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KFY00117.1 - 1.2e-15 57.9 0.0 1.5e-15 57.6 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KFY00117.1 - 0.0036 16.8 0.0 0.023 14.2 0.0 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Alpha-amylase PF00128.24 KFY00118.1 - 2.1e-53 182.1 0.0 3.9e-53 181.2 0.0 1.4 1 1 0 1 1 1 1 Alpha amylase, catalytic domain DUF1966 PF09260.11 KFY00118.1 - 5.6e-13 49.0 0.1 1.6e-12 47.5 0.1 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1966) MFS_1 PF07690.16 KFY00118.1 - 7.2e-13 48.2 45.5 3.2e-12 46.1 45.1 2.6 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 KFY00118.1 - 0.0026 16.3 21.5 0.51 8.7 21.5 2.3 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) hDGE_amylase PF14701.6 KFY00118.1 - 0.14 11.2 0.0 0.22 10.6 0.0 1.2 1 0 0 1 1 1 0 Glycogen debranching enzyme, glucanotransferase domain GHL10 PF02638.15 KFY00118.1 - 0.15 11.1 0.0 0.26 10.3 0.0 1.3 1 0 0 1 1 1 0 Glycosyl hydrolase-like 10 DUF1428 PF07237.11 KFY00118.1 - 0.16 12.2 0.0 0.39 11.0 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1428) Pyr_redox_2 PF07992.14 KFY00119.1 - 1.1e-27 97.0 0.0 1.5e-27 96.6 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KFY00119.1 - 3.3e-09 37.2 0.4 1.2e-07 32.2 0.0 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KFY00119.1 - 0.0023 17.2 1.5 4 6.6 0.5 3.8 3 1 0 4 4 4 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KFY00119.1 - 0.089 11.9 0.2 0.29 10.3 0.0 1.9 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) ADH_N_2 PF16884.5 KFY00122.1 - 0.017 15.0 0.0 0.071 13.0 0.0 2.0 1 1 0 1 1 1 0 N-terminal domain of oxidoreductase Acetyltransf_3 PF13302.7 KFY00123.1 - 2.3e-05 25.1 0.0 5.2e-05 23.9 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KFY00123.1 - 0.013 15.7 0.0 0.029 14.6 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family F-box PF00646.33 KFY00123.1 - 0.12 12.3 0.1 0.39 10.6 0.1 1.8 1 0 0 1 1 1 0 F-box domain Peptidase_S8 PF00082.22 KFY00126.1 - 9.6e-25 87.4 21.8 1.9e-24 86.4 21.8 1.5 1 1 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.16 KFY00126.1 - 6.8e-08 33.1 0.1 1.2e-07 32.3 0.1 1.4 1 0 0 1 1 1 1 Peptidase inhibitor I9 Ndc1_Nup PF09531.10 KFY00127.1 - 1.3 7.6 4.1 1.3 7.6 4.1 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Presenilin PF01080.17 KFY00127.1 - 4.2 6.0 12.1 4.4 6.0 12.1 1.1 1 0 0 1 1 1 0 Presenilin Hid1 PF12722.7 KFY00127.1 - 5.3 5.1 7.6 5.3 5.1 7.6 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein CDC45 PF02724.14 KFY00127.1 - 8.1 4.6 14.0 9.3 4.4 14.0 1.1 1 0 0 1 1 1 0 CDC45-like protein LPMO_10 PF03067.15 KFY00129.1 - 0.046 14.4 0.5 0.38 11.4 0.5 2.0 1 1 0 1 1 1 0 Lytic polysaccharide mono-oxygenase, cellulose-degrading Glyco_hydro_18 PF00704.28 KFY00130.1 - 2.3e-86 290.4 2.4 2.6e-86 290.2 2.4 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Peptidase_M16_C PF05193.21 KFY00130.1 - 0.041 13.9 0.0 0.075 13.0 0.0 1.4 1 0 0 1 1 1 0 Peptidase M16 inactive domain PhyH PF05721.13 KFY00131.1 - 1.2e-05 25.6 0.3 0.00011 22.5 0.3 2.0 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) Fungal_trans_2 PF11951.8 KFY00132.1 - 1.4e-20 73.5 3.7 7.9e-18 64.4 1.3 2.1 2 0 0 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.18 KFY00132.1 - 0.0067 16.5 1.7 0.014 15.5 1.7 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Sugar_tr PF00083.24 KFY00133.1 - 6.4e-79 265.9 22.9 7.6e-79 265.7 22.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KFY00133.1 - 2.5e-30 105.6 23.5 2.5e-30 105.6 23.5 1.7 1 1 1 2 2 2 1 Major Facilitator Superfamily MFS_4 PF06779.14 KFY00133.1 - 1.8e-05 24.2 3.5 1.8e-05 24.2 3.5 2.5 2 1 1 3 3 3 1 Uncharacterised MFS-type transporter YbfB TRI12 PF06609.13 KFY00133.1 - 3.3e-05 22.5 0.7 3.3e-05 22.5 0.7 2.1 2 0 0 2 2 2 2 Fungal trichothecene efflux pump (TRI12) OATP PF03137.20 KFY00133.1 - 1.1 7.5 13.4 0.035 12.4 0.6 2.5 2 1 1 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family Abhydrolase_2 PF02230.16 KFY00134.1 - 2.5e-11 43.8 0.4 2.6e-07 30.7 0.0 2.1 1 1 1 2 2 2 2 Phospholipase/Carboxylesterase GFO_IDH_MocA PF01408.22 KFY00135.1 - 8.2e-15 55.7 0.0 1.3e-14 55.0 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 KFY00135.1 - 5.8e-07 29.5 0.0 8.1e-07 29.1 0.0 1.2 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain Mannosidase_ig PF17786.1 KFY00136.1 - 1.3e-10 41.8 0.1 5.7e-10 39.7 0.0 2.1 2 0 0 2 2 2 1 Mannosidase Ig/CBM-like domain Ig_mannosidase PF17753.1 KFY00136.1 - 1.4e-06 27.9 0.0 3.2e-06 26.8 0.0 1.6 1 0 0 1 1 1 1 Ig-fold domain Glyco_hydro_2 PF00703.21 KFY00136.1 - 1.8e-06 28.6 0.1 4.3e-06 27.4 0.1 1.7 1 0 0 1 1 1 1 Glycosyl hydrolases family 2 Glyco_hydro_2_N PF02837.18 KFY00136.1 - 0.001 19.0 0.0 0.0022 18.0 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain Ig_GlcNase PF18368.1 KFY00136.1 - 0.061 13.5 0.0 0.22 11.7 0.0 1.9 1 0 0 1 1 1 0 Exo-beta-D-glucosaminidase Ig-fold domain UQ_con PF00179.26 KFY00144.1 - 5.1e-47 159.0 0.1 1.1e-46 157.9 0.0 1.6 2 0 0 2 2 2 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 KFY00144.1 - 0.0021 17.7 0.0 0.0031 17.2 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.13 KFY00144.1 - 0.0092 15.8 0.1 0.017 14.9 0.1 1.4 1 1 0 1 1 1 1 UEV domain RWD PF05773.22 KFY00144.1 - 0.35 11.2 2.1 0.7 10.2 2.1 1.7 1 1 0 1 1 1 0 RWD domain Methyltransf_24 PF13578.6 KFY00145.1 - 3.2e-11 44.2 0.0 2.1e-10 41.5 0.0 2.6 2 0 0 2 2 2 1 Methyltransferase domain WD40 PF00400.32 KFY00145.1 - 2.2e-06 28.3 15.8 0.0035 18.1 0.1 5.3 4 0 0 4 4 4 3 WD domain, G-beta repeat Methyltransf_3 PF01596.17 KFY00145.1 - 3.7e-05 23.0 0.1 9.6e-05 21.6 0.1 1.6 1 1 0 1 1 1 1 O-methyltransferase Zn_ribbon_17 PF17120.5 KFY00145.1 - 0.00034 20.2 11.1 0.0007 19.2 11.1 1.5 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-RING_2 PF13639.6 KFY00145.1 - 0.55 10.6 5.6 1.2 9.5 5.6 1.6 1 0 0 1 1 1 0 Ring finger domain HET PF06985.11 KFY00146.1 - 9e-11 42.3 0.0 1.8e-09 38.1 0.0 2.3 1 1 1 2 2 2 1 Heterokaryon incompatibility protein (HET) GFA PF04828.14 KFY00146.1 - 6.2e-10 39.3 0.2 1.5e-09 38.0 0.2 1.7 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme adh_short_C2 PF13561.6 KFY00147.1 - 2.2e-52 178.0 0.0 3.1e-52 177.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KFY00147.1 - 3.2e-49 167.1 0.2 3.9e-49 166.8 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KFY00147.1 - 2.8e-10 40.4 0.0 3.7e-10 40.0 0.0 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KFY00147.1 - 0.001 18.6 0.0 0.0014 18.2 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF1776 PF08643.10 KFY00147.1 - 0.0031 17.0 0.0 0.0044 16.4 0.0 1.2 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) PALP PF00291.25 KFY00147.1 - 0.012 15.1 0.0 0.018 14.5 0.0 1.3 1 0 0 1 1 1 0 Pyridoxal-phosphate dependent enzyme 2-Hacid_dh_C PF02826.19 KFY00147.1 - 0.017 14.5 0.2 0.62 9.4 0.1 2.3 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_7 PF13241.6 KFY00147.1 - 0.026 14.9 0.5 0.069 13.6 0.5 1.6 1 0 0 1 1 1 0 Putative NAD(P)-binding THF_DHG_CYH_C PF02882.19 KFY00147.1 - 0.044 13.1 0.0 0.092 12.1 0.0 1.5 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain GDP_Man_Dehyd PF16363.5 KFY00147.1 - 0.067 12.6 0.0 0.094 12.1 0.0 1.2 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase Eno-Rase_NADH_b PF12242.8 KFY00147.1 - 0.14 12.0 0.1 0.4 10.5 0.1 1.8 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase PBP_like_2 PF12849.7 KFY00148.1 - 5.9e-09 36.0 0.1 7.7e-09 35.6 0.1 1.1 1 0 0 1 1 1 1 PBP superfamily domain CBM_1 PF00734.18 KFY00149.1 - 1.8e-08 34.1 11.6 4.2e-08 33.0 11.6 1.7 1 0 0 1 1 1 1 Fungal cellulose binding domain CBM_11 PF03425.13 KFY00149.1 - 0.11 12.3 0.0 0.23 11.3 0.0 1.4 1 0 0 1 1 1 0 Carbohydrate binding domain (family 11) RTA1 PF04479.13 KFY00150.1 - 2.6e-38 131.7 10.6 4.6e-38 130.9 10.6 1.3 1 0 0 1 1 1 1 RTA1 like protein Zn_clus PF00172.18 KFY00151.1 - 8.6e-09 35.4 5.1 1.9e-08 34.3 5.1 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 KFY00151.1 - 0.021 13.6 1.5 0.033 13.0 1.5 1.2 1 0 0 1 1 1 0 Fungal specific transcription factor domain Flavoprotein PF02441.19 KFY00152.1 - 9.2e-44 149.0 0.0 1.1e-43 148.7 0.0 1.1 1 0 0 1 1 1 1 Flavoprotein Glyco_hydro_45 PF02015.16 KFY00153.1 - 5e-55 186.7 15.1 6.2e-55 186.4 15.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 45 Rhv PF00073.20 KFY00154.1 - 0.086 12.4 0.0 0.13 11.9 0.0 1.3 1 0 0 1 1 1 0 picornavirus capsid protein DUF4293 PF14126.6 KFY00154.1 - 0.24 11.7 6.1 0.048 13.9 1.5 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4293) Fasciclin PF02469.22 KFY00155.1 - 2.1e-38 131.4 0.0 3.6e-20 72.5 0.0 2.2 2 0 0 2 2 2 2 Fasciclin domain Kp4 PF09044.10 KFY00156.1 - 3.8e-24 85.2 3.0 4.6e-24 84.9 3.0 1.0 1 0 0 1 1 1 1 Kp4 MU117 PF15474.6 KFY00156.1 - 0.0042 17.9 0.7 0.0059 17.4 0.7 1.2 1 0 0 1 1 1 1 Meiotically up-regulated gene family Ank_2 PF12796.7 KFY00157.1 - 3.2e-57 191.1 31.7 3.8e-14 53.0 0.2 7.8 2 2 7 9 9 9 9 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KFY00157.1 - 2.8e-39 133.0 9.7 1.1e-08 35.4 0.0 9.5 6 2 1 9 9 9 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFY00157.1 - 1.7e-35 117.0 4.3 0.032 14.8 0.0 12.6 12 0 0 12 12 12 9 Ankyrin repeat Ank_5 PF13857.6 KFY00157.1 - 3.3e-31 106.9 14.7 0.0006 20.1 0.1 12.4 6 3 5 12 12 12 8 Ankyrin repeats (many copies) Ank PF00023.30 KFY00157.1 - 2.8e-28 97.1 16.2 0.0074 16.7 0.7 11.5 12 0 0 12 12 12 7 Ankyrin repeat CorA PF01544.18 KFY00157.1 - 1.1e-06 28.2 0.0 3.1e-06 26.7 0.0 1.8 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein TF_AP-2 PF03299.14 KFY00157.1 - 0.012 15.6 1.1 0.033 14.2 1.1 1.7 1 0 0 1 1 1 0 Transcription factor AP-2 VWA_3_C PF18571.1 KFY00157.1 - 0.054 13.4 3.9 0.53 10.2 0.1 4.0 4 0 0 4 4 4 0 von Willebrand factor type A C-terminal domain MFS_1 PF07690.16 KFY00161.1 - 2.2e-12 46.6 8.8 2.9e-12 46.2 8.8 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Glyco_hydro_76 PF03663.14 KFY00163.1 - 3.6e-160 533.5 14.8 4.2e-160 533.2 14.8 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Synaptobrevin PF00957.21 KFY00164.1 - 4.1e-27 93.8 0.4 4.9e-27 93.5 0.4 1.0 1 0 0 1 1 1 1 Synaptobrevin GP41 PF00517.17 KFY00164.1 - 0.036 14.0 0.0 0.049 13.5 0.0 1.2 1 0 0 1 1 1 0 Retroviral envelope protein DUF3618 PF12277.8 KFY00164.1 - 0.08 13.2 0.3 0.34 11.2 0.1 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3618) Abhydrolase_2 PF02230.16 KFY00164.1 - 0.11 12.3 0.0 0.11 12.3 0.0 1.0 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase DUF2207 PF09972.9 KFY00164.1 - 0.16 10.7 0.0 0.18 10.5 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Sec20 PF03908.13 KFY00164.1 - 0.22 11.5 2.3 0.59 10.1 2.3 1.6 1 1 0 1 1 1 0 Sec20 Fzo_mitofusin PF04799.13 KFY00164.1 - 0.62 9.6 6.0 0.095 12.2 0.5 1.9 1 1 1 2 2 2 0 fzo-like conserved region NAT PF04768.13 KFY00165.1 - 1.7e-52 177.5 0.6 3.2e-52 176.6 0.2 1.6 2 0 0 2 2 2 1 NAT, N-acetyltransferase, of N-acetylglutamate synthase AA_kinase PF00696.28 KFY00165.1 - 6.7e-31 107.7 0.0 1.2e-30 106.8 0.0 1.4 1 0 0 1 1 1 1 Amino acid kinase family Semialdhyde_dh PF01118.24 KFY00165.1 - 2.2e-30 105.6 0.0 5.1e-30 104.4 0.0 1.7 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain DapB_N PF01113.20 KFY00165.1 - 0.079 13.1 0.0 0.35 11.0 0.0 2.1 2 0 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus Arm PF00514.23 KFY00165.1 - 0.17 12.0 0.2 1.8 8.7 0.0 2.6 2 0 0 2 2 2 0 Armadillo/beta-catenin-like repeat 5_nucleotid_C PF02872.18 KFY00166.1 - 0.0062 16.8 0.0 0.015 15.5 0.0 1.6 1 0 0 1 1 1 1 5'-nucleotidase, C-terminal domain RRM_1 PF00076.22 KFY00166.1 - 0.026 14.4 0.0 0.064 13.1 0.0 1.8 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF1687 PF07955.11 KFY00167.1 - 3.9e-30 104.9 0.1 5.1e-30 104.6 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1687) CAP PF00188.26 KFY00167.1 - 0.071 13.9 0.3 0.092 13.6 0.3 1.2 1 0 0 1 1 1 0 Cysteine-rich secretory protein family NAC PF01849.18 KFY00168.1 - 4.6e-22 77.7 0.3 9e-22 76.8 0.3 1.5 1 0 0 1 1 1 1 NAC domain Nup35_RRM PF05172.13 KFY00168.1 - 0.0063 16.5 0.0 0.015 15.2 0.0 1.6 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif AdoMet_MTase PF07757.13 KFY00169.1 - 9e-40 135.5 0.0 1.4e-39 134.9 0.0 1.3 1 0 0 1 1 1 1 Predicted AdoMet-dependent methyltransferase Methyltransf_32 PF13679.6 KFY00169.1 - 0.0067 16.4 0.0 0.02 14.9 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KFY00169.1 - 0.13 12.0 0.0 0.23 11.3 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Ribosomal_L24e PF01246.20 KFY00170.1 - 4.1e-28 97.4 0.4 9.9e-28 96.2 0.4 1.7 1 0 0 1 1 1 1 Ribosomal protein L24e CBP4 PF07960.11 KFY00171.1 - 2.9e-27 95.1 0.5 3.5e-27 94.8 0.5 1.0 1 0 0 1 1 1 1 CBP4 Seryl_tRNA_N PF02403.22 KFY00171.1 - 0.19 12.0 6.9 0.37 11.0 6.9 1.4 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain Sel1 PF08238.12 KFY00172.1 - 1.2e-37 127.4 24.7 4.3e-08 33.6 0.1 7.8 7 0 0 7 7 7 6 Sel1 repeat ANAPC3 PF12895.7 KFY00172.1 - 0.078 13.2 2.0 12 6.2 0.2 2.9 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.6 KFY00172.1 - 1 10.1 7.0 30 5.5 0.1 4.1 3 0 0 3 3 3 0 Tetratricopeptide repeat Hce2 PF14856.6 KFY00173.1 - 7.7e-17 61.5 0.0 1.1e-16 61.0 0.0 1.2 1 0 0 1 1 1 1 Pathogen effector; putative necrosis-inducing factor CRCB PF02537.15 KFY00174.1 - 1.8e-35 121.1 14.8 1.5e-22 79.7 8.5 2.5 2 0 0 2 2 2 2 CrcB-like protein, Camphor Resistance (CrcB) MFS_1 PF07690.16 KFY00175.1 - 1.4e-29 103.1 67.6 2.1e-15 56.5 32.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Amidase PF01425.21 KFY00176.1 - 6.5e-98 328.6 0.0 4.2e-97 325.9 0.0 1.9 1 1 0 1 1 1 1 Amidase AMP-binding PF00501.28 KFY00177.1 - 2.5e-147 490.9 0.4 6.1e-64 216.2 0.0 3.3 3 0 0 3 3 3 3 AMP-binding enzyme Condensation PF00668.20 KFY00177.1 - 9.4e-111 370.7 0.0 7.1e-36 123.9 0.0 5.3 5 0 0 5 5 5 5 Condensation domain PP-binding PF00550.25 KFY00177.1 - 2e-22 79.3 0.1 2.2e-10 40.7 0.2 3.0 2 0 0 2 2 2 2 Phosphopantetheine attachment site AMP-binding_C PF13193.6 KFY00177.1 - 0.0008 20.3 0.0 3 8.9 0.0 3.0 2 0 0 2 2 2 2 AMP-binding enzyme C-terminal domain ABC_tran PF00005.27 KFY00178.1 - 3.8e-49 166.7 0.0 4.8e-29 101.6 0.0 2.6 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 KFY00178.1 - 1.6e-30 106.7 19.4 8.8e-25 87.9 7.5 2.3 2 0 0 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.19 KFY00178.1 - 3.5e-11 43.0 0.9 0.018 14.5 0.1 4.3 4 0 0 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 KFY00178.1 - 1.9e-10 41.0 5.9 0.016 15.0 0.2 4.3 3 1 1 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 KFY00178.1 - 2.6e-08 34.2 1.8 0.013 15.8 0.0 3.8 3 1 0 3 3 3 2 AAA domain AAA_29 PF13555.6 KFY00178.1 - 3.9e-08 32.9 0.1 0.013 15.2 0.0 2.9 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 KFY00178.1 - 1.1e-07 31.9 0.0 0.003 17.5 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase AAA_16 PF13191.6 KFY00178.1 - 6.6e-07 29.9 0.0 0.16 12.3 0.0 3.7 3 1 0 3 3 3 2 AAA ATPase domain AAA_23 PF13476.6 KFY00178.1 - 1.7e-06 28.7 0.2 0.012 16.2 0.0 2.5 2 0 0 2 2 2 2 AAA domain T2SSE PF00437.20 KFY00178.1 - 2.2e-05 23.7 0.1 0.13 11.3 0.0 2.4 2 0 0 2 2 2 2 Type II/IV secretion system protein MMR_HSR1 PF01926.23 KFY00178.1 - 5.6e-05 23.2 0.1 0.14 12.2 0.0 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_7 PF12775.7 KFY00178.1 - 7.5e-05 22.3 0.1 0.45 10.0 0.0 2.6 3 0 0 3 3 2 2 P-loop containing dynein motor region AAA_24 PF13479.6 KFY00178.1 - 8.5e-05 22.4 0.3 0.055 13.2 0.1 2.6 2 1 0 2 2 2 1 AAA domain DUF87 PF01935.17 KFY00178.1 - 0.00014 22.1 1.3 0.035 14.2 0.0 2.4 2 0 0 2 2 2 1 Helicase HerA, central domain Dynamin_N PF00350.23 KFY00178.1 - 0.00047 20.3 0.0 0.55 10.3 0.0 2.6 2 0 0 2 2 2 2 Dynamin family AAA PF00004.29 KFY00178.1 - 0.00064 20.2 0.1 3.5 8.1 0.0 3.5 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) IstB_IS21 PF01695.17 KFY00178.1 - 0.00069 19.4 0.1 5.2 6.8 0.1 3.4 3 0 0 3 3 3 0 IstB-like ATP binding protein cobW PF02492.19 KFY00178.1 - 0.0009 18.9 0.6 0.19 11.3 0.2 2.5 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_15 PF13175.6 KFY00178.1 - 0.0012 18.6 0.3 0.58 9.8 0.1 2.7 2 1 1 3 3 3 1 AAA ATPase domain FtsK_SpoIIIE PF01580.18 KFY00178.1 - 0.0013 18.2 0.0 0.34 10.2 0.0 2.3 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA_30 PF13604.6 KFY00178.1 - 0.0015 18.3 0.3 2.5 7.8 0.1 3.0 2 1 0 2 2 2 1 AAA domain Zeta_toxin PF06414.12 KFY00178.1 - 0.0027 17.0 0.1 3.5 6.9 0.0 2.8 3 0 0 3 3 3 2 Zeta toxin ATPase_2 PF01637.18 KFY00178.1 - 0.0033 17.4 0.0 0.58 10.0 0.0 2.5 2 0 0 2 2 2 1 ATPase domain predominantly from Archaea AAA_33 PF13671.6 KFY00178.1 - 0.0033 17.6 0.0 1.7 8.8 0.1 2.5 2 0 0 2 2 2 1 AAA domain NB-ARC PF00931.22 KFY00178.1 - 0.0034 16.6 0.0 2.4 7.3 0.0 2.5 2 0 0 2 2 2 2 NB-ARC domain NACHT PF05729.12 KFY00178.1 - 0.0059 16.5 0.9 20 5.1 0.1 3.9 3 0 0 3 3 3 0 NACHT domain AAA_18 PF13238.6 KFY00178.1 - 0.006 17.1 0.0 2 9.0 0.0 2.6 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 KFY00178.1 - 0.01 16.2 0.0 8 6.9 0.0 2.9 3 0 0 3 3 2 0 RNA helicase Viral_helicase1 PF01443.18 KFY00178.1 - 0.017 14.8 0.1 10 5.8 0.0 3.0 3 0 0 3 3 3 0 Viral (Superfamily 1) RNA helicase DUF815 PF05673.13 KFY00178.1 - 0.04 13.1 0.0 1.7 7.7 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) Adeno_IVa2 PF02456.15 KFY00178.1 - 0.071 11.9 0.1 1.2 7.9 0.0 2.1 2 0 0 2 2 2 0 Adenovirus IVa2 protein SbcCD_C PF13558.6 KFY00178.1 - 0.072 13.3 0.0 6.4 7.1 0.0 2.9 2 0 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_5 PF07728.14 KFY00178.1 - 0.11 12.6 1.8 27 4.8 0.3 3.6 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_25 PF13481.6 KFY00178.1 - 0.11 12.1 0.1 4.7 6.7 0.0 2.8 2 0 0 2 2 2 0 AAA domain TsaE PF02367.17 KFY00178.1 - 0.11 12.4 0.0 19 5.2 0.0 2.5 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE ATP-synt_ab PF00006.25 KFY00178.1 - 0.12 12.0 0.0 2 8.0 0.0 2.3 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain dNK PF01712.19 KFY00178.1 - 0.15 11.9 0.2 1.1 9.1 0.0 2.1 2 0 0 2 2 2 0 Deoxynucleoside kinase ATP_bind_1 PF03029.17 KFY00178.1 - 0.21 11.4 0.2 14 5.4 0.0 2.6 3 0 0 3 3 2 0 Conserved hypothetical ATP binding protein NTPase_1 PF03266.15 KFY00178.1 - 0.55 10.1 3.5 11 5.9 0.1 3.3 4 0 0 4 4 3 0 NTPase Zn_clus PF00172.18 KFY00179.1 - 1.2e-06 28.6 11.7 1.2e-06 28.6 11.7 1.9 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-C2H2 PF00096.26 KFY00179.1 - 0.0019 18.5 0.3 0.0089 16.4 0.3 2.2 1 0 0 1 1 1 1 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.8 KFY00179.1 - 0.042 14.1 0.2 0.13 12.6 0.0 2.0 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding adh_short PF00106.25 KFY00180.1 - 3.5e-29 101.7 0.3 4.4e-29 101.3 0.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KFY00180.1 - 1.8e-21 76.8 0.1 5.8e-21 75.1 0.1 1.7 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KFY00180.1 - 1.1e-14 54.8 0.2 1.7e-14 54.1 0.2 1.2 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 KFY00180.1 - 3.4e-06 26.4 0.1 4.2e-06 26.1 0.1 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Epimerase PF01370.21 KFY00180.1 - 0.00013 21.6 0.1 0.0002 20.9 0.1 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 KFY00180.1 - 0.016 14.3 0.1 0.025 13.7 0.1 1.3 1 0 0 1 1 1 0 RmlD substrate binding domain Pyr_redox_2 PF07992.14 KFY00180.1 - 0.088 12.0 0.0 0.13 11.4 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Fungal_trans PF04082.18 KFY00181.1 - 9.9e-15 54.3 0.3 2e-14 53.3 0.3 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KFY00181.1 - 2.5e-07 30.7 8.3 4.6e-07 29.8 8.3 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain adh_short PF00106.25 KFY00182.1 - 3.4e-34 118.0 0.1 3.3e-24 85.4 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KFY00182.1 - 7.5e-23 81.3 0.0 1.5e-20 73.8 0.0 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KFY00182.1 - 4.6e-08 33.2 0.0 7.5e-08 32.5 0.0 1.3 1 0 0 1 1 1 1 KR domain DUF1521 PF07481.11 KFY00182.1 - 0.018 15.1 0.1 0.039 14.0 0.1 1.5 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1521) Adeno_100 PF02438.16 KFY00182.1 - 0.052 11.7 0.0 0.067 11.4 0.0 1.1 1 0 0 1 1 1 0 Late 100kD protein Epimerase PF01370.21 KFY00182.1 - 0.08 12.4 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 KFY00182.1 - 0.089 12.7 0.0 0.27 11.1 0.0 1.8 1 1 0 1 1 1 0 NAD(P)H-binding CDC48_N PF02359.18 KFY00182.1 - 0.09 13.0 0.0 0.23 11.7 0.0 1.6 1 0 0 1 1 1 0 Cell division protein 48 (CDC48), N-terminal domain GDP_Man_Dehyd PF16363.5 KFY00182.1 - 0.16 11.3 0.0 0.21 11.0 0.0 1.2 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase MIT PF04212.18 KFY00183.1 - 2.8e-19 68.9 6.0 8.2e-19 67.4 6.0 1.9 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain FAD_binding_4 PF01565.23 KFY00183.1 - 3.1e-14 52.9 0.0 8.1e-14 51.5 0.0 1.8 1 0 0 1 1 1 1 FAD binding domain FAD-oxidase_C PF02913.19 KFY00183.1 - 6.3e-07 29.3 0.0 1.5e-06 28.1 0.0 1.6 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain Helo_like_N PF17111.5 KFY00183.1 - 7e-05 22.3 0.0 0.00019 20.9 0.0 1.7 1 0 0 1 1 1 1 Fungal N-terminal domain of STAND proteins Abhydrolase_2 PF02230.16 KFY00184.1 - 2.9e-57 194.0 0.0 4.6e-57 193.3 0.0 1.3 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase LigB PF02900.18 KFY00184.1 - 1.6e-12 47.0 0.0 1.5e-08 34.1 0.0 2.2 2 0 0 2 2 2 2 Catalytic LigB subunit of aromatic ring-opening dioxygenase EFG_C PF00679.24 KFY00184.1 - 1.2e-06 28.5 0.0 3.7e-06 26.9 0.0 1.8 2 0 0 2 2 2 1 Elongation factor G C-terminus DLH PF01738.18 KFY00184.1 - 2.5e-05 24.0 0.0 4.5e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 Dienelactone hydrolase family Peptidase_S9 PF00326.21 KFY00184.1 - 0.00011 21.7 0.4 0.017 14.6 0.0 2.4 1 1 1 2 2 2 2 Prolyl oligopeptidase family FSH1 PF03959.13 KFY00184.1 - 0.00034 20.3 0.0 0.0008 19.1 0.0 1.6 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_6 PF12697.7 KFY00184.1 - 0.0011 19.6 3.2 0.0033 18.1 0.2 2.4 2 0 0 2 2 2 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KFY00184.1 - 0.0042 16.4 0.2 4.4 6.5 0.0 3.1 2 1 1 3 3 3 2 Serine aminopeptidase, S33 Abhydrolase_3 PF07859.13 KFY00184.1 - 0.06 13.2 0.1 6.3 6.6 0.1 2.3 1 1 1 2 2 2 0 alpha/beta hydrolase fold Abhydrolase_1 PF00561.20 KFY00184.1 - 0.11 12.1 0.2 0.63 9.6 0.2 2.0 1 1 0 1 1 1 0 alpha/beta hydrolase fold DUF2920 PF11144.8 KFY00184.1 - 0.28 10.3 0.0 6.2 5.9 0.0 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2920) adh_short PF00106.25 KFY00191.1 - 0.00098 18.6 0.0 0.098 12.1 0.0 3.2 3 1 0 3 3 3 1 short chain dehydrogenase TMF_DNA_bd PF12329.8 KFY00191.1 - 0.014 15.4 0.4 0.025 14.6 0.4 1.4 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding Imm_superinfect PF14373.6 KFY00191.1 - 0.019 14.9 0.4 0.048 13.6 0.4 1.7 1 0 0 1 1 1 0 Superinfection immunity protein Acetyltransf_8 PF13523.6 KFY00192.1 - 3.7e-48 162.9 0.1 5.6e-48 162.3 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 KFY00192.1 - 0.026 15.2 0.0 0.048 14.3 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Fimbrial_K88 PF02432.15 KFY00193.1 - 0.011 15.7 2.1 0.047 13.7 0.1 2.3 1 1 1 2 2 2 0 Fimbrial, major and minor subunit NAD_binding_10 PF13460.6 KFY00194.1 - 1e-05 25.5 0.0 1.3e-05 25.2 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KFY00194.1 - 0.00018 21.0 0.0 0.0002 20.9 0.0 1.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KFY00194.1 - 0.00074 18.6 0.0 0.0009 18.3 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family DapB_N PF01113.20 KFY00194.1 - 0.0071 16.5 0.0 0.012 15.7 0.0 1.5 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus Semialdhyde_dh PF01118.24 KFY00194.1 - 0.075 13.5 0.0 0.22 12.0 0.0 1.8 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain DXP_reductoisom PF02670.16 KFY00194.1 - 0.12 13.1 0.0 0.19 12.5 0.0 1.3 1 0 0 1 1 1 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase Melibiase_2 PF16499.5 KFY00195.1 - 1.6e-32 112.8 0.5 2.3e-32 112.3 0.5 1.2 1 0 0 1 1 1 1 Alpha galactosidase A Melibiase_C PF17801.1 KFY00195.1 - 6.9e-10 38.9 0.4 1.8e-09 37.5 0.3 1.8 2 0 0 2 2 2 1 Alpha galactosidase C-terminal beta sandwich domain Baculo_PEP_C PF04513.12 KFY00196.1 - 8.5e-09 35.6 0.0 2.6 8.1 0.0 6.4 4 2 3 7 7 7 5 Baculovirus polyhedron envelope protein, PEP, C terminus Collagen_mid PF15984.5 KFY00196.1 - 4.8e-05 23.2 8.9 4.8e-05 23.2 8.9 7.1 1 1 5 6 6 6 2 Bacterial collagen, middle region zf-ZPR1 PF03367.13 KFY00196.1 - 0.002 18.0 6.0 14 5.5 0.1 5.5 2 1 4 6 6 6 1 ZPR1 zinc-finger domain HypD PF01924.16 KFY00196.1 - 0.004 16.3 4.0 3.5 6.6 0.0 3.9 2 1 1 4 4 4 2 Hydrogenase formation hypA family YadA_stalk PF05662.14 KFY00196.1 - 0.3 11.5 17.1 6.6 7.2 0.5 6.0 6 0 0 6 6 6 0 Coiled stalk of trimeric autotransporter adhesin Plasmid_stab_B PF10784.9 KFY00196.1 - 4.5 7.2 6.8 47 3.9 0.1 3.5 3 0 0 3 3 3 0 Plasmid stability protein APH PF01636.23 KFY00197.1 - 2e-14 54.1 0.0 2.9e-14 53.6 0.0 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family O-FucT PF10250.9 KFY00211.1 - 2e-07 31.0 0.0 4.8e-07 29.8 0.0 1.6 1 1 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase VSP PF03302.13 KFY00212.1 - 0.025 13.5 0.0 0.033 13.0 0.0 1.2 1 0 0 1 1 1 0 Giardia variant-specific surface protein DUF2207 PF09972.9 KFY00212.1 - 0.14 10.9 0.0 0.19 10.4 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) TraL PF07178.11 KFY00212.1 - 0.23 12.0 0.3 3.3 8.2 0.2 2.6 3 0 0 3 3 3 0 TraL protein SNF2_N PF00176.23 KFY00213.1 - 3.6e-64 216.7 0.3 8.2e-64 215.5 0.1 1.6 2 0 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KFY00213.1 - 9.3e-22 77.5 0.0 2.5e-21 76.1 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KFY00213.1 - 6.8e-08 32.7 0.0 2.1e-07 31.1 0.0 1.9 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 KFY00213.1 - 5.7e-05 22.9 0.0 0.00015 21.6 0.0 1.8 1 0 0 1 1 1 1 DEAD/DEAH box helicase HDA2-3 PF11496.8 KFY00213.1 - 0.0001 21.6 0.0 0.068 12.3 0.0 2.9 2 1 0 2 2 2 2 Class II histone deacetylase complex subunits 2 and 3 ERCC3_RAD25_C PF16203.5 KFY00213.1 - 0.00029 20.1 0.0 0.00056 19.2 0.0 1.4 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase Mit_KHE1 PF10173.9 KFY00214.1 - 6.5e-60 202.5 1.3 6.9e-60 202.4 0.0 1.6 2 0 0 2 2 2 1 Mitochondrial K+-H+ exchange-related Pterin_bind PF00809.22 KFY00216.1 - 1.1e-75 254.4 0.0 1.5e-75 254.0 0.0 1.1 1 0 0 1 1 1 1 Pterin binding enzyme HPPK PF01288.20 KFY00216.1 - 7.7e-36 123.0 0.0 2e-35 121.6 0.0 1.8 1 0 0 1 1 1 1 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) NMO PF03060.15 KFY00217.1 - 3.1e-57 194.4 1.7 4.3e-57 194.0 1.7 1.2 1 0 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.25 KFY00217.1 - 1.6e-11 43.8 1.9 7.6e-11 41.6 1.9 1.9 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.18 KFY00217.1 - 3.3e-08 33.0 1.8 5.8e-08 32.1 1.8 1.3 1 0 0 1 1 1 1 FMN-dependent dehydrogenase DHO_dh PF01180.21 KFY00217.1 - 0.0001 21.6 0.3 0.00016 21.0 0.3 1.3 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase Glu_synthase PF01645.17 KFY00217.1 - 0.0017 17.6 0.4 0.0034 16.6 0.4 1.5 1 0 0 1 1 1 1 Conserved region in glutamate synthase FAD_binding_4 PF01565.23 KFY00218.1 - 2e-23 82.7 3.3 3.5e-23 81.9 3.3 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 KFY00218.1 - 0.00082 19.4 0.0 0.002 18.2 0.0 1.6 1 0 0 1 1 1 1 Berberine and berberine like DUF1180 PF06679.12 KFY00219.1 - 1.8 9.0 5.7 1.9 8.9 5.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) Hamartin PF04388.12 KFY00219.1 - 2.7 6.6 5.5 2.5 6.7 5.5 1.0 1 0 0 1 1 1 0 Hamartin protein Cupin_8 PF13621.6 KFY00220.1 - 2.2e-31 109.5 0.0 3.7e-31 108.8 0.0 1.3 1 0 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.12 KFY00220.1 - 3.4e-07 30.1 0.0 1.9e-05 24.3 0.0 2.2 2 0 0 2 2 2 1 Cupin superfamily protein Ribul_P_3_epim PF00834.19 KFY00220.1 - 0.0012 18.3 0.0 0.0019 17.6 0.0 1.2 1 0 0 1 1 1 1 Ribulose-phosphate 3 epimerase family RCDG1 PF15725.5 KFY00220.1 - 0.0086 16.5 1.4 0.021 15.2 0.2 2.1 2 0 0 2 2 2 1 Renal cancer differentiation gene 1 protein JmjC PF02373.22 KFY00220.1 - 0.016 15.6 0.0 0.054 13.9 0.0 1.8 2 0 0 2 2 2 0 JmjC domain, hydroxylase Cupin_2 PF07883.11 KFY00220.1 - 0.12 12.1 0.0 0.34 10.7 0.0 1.7 1 0 0 1 1 1 0 Cupin domain WD40 PF00400.32 KFY00232.1 - 1.9e-08 34.8 5.7 0.0049 17.7 0.4 3.9 4 0 0 4 4 4 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFY00232.1 - 0.0004 20.6 0.1 0.025 14.9 0.1 2.9 2 1 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KFY00232.1 - 0.0033 16.1 0.3 0.0057 15.4 0.3 1.3 1 0 0 1 1 1 1 Nucleoporin Nup120/160 FYVE PF01363.21 KFY00233.1 - 0.0042 17.2 0.5 0.0045 17.1 0.5 1.2 1 0 0 1 1 1 1 FYVE zinc finger Prok-RING_1 PF14446.6 KFY00233.1 - 0.0091 15.9 5.5 0.015 15.2 5.5 1.3 1 0 0 1 1 1 1 Prokaryotic RING finger family 1 zf-RING_4 PF14570.6 KFY00233.1 - 0.031 14.1 5.2 0.049 13.4 5.2 1.3 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Prok-RING_2 PF14445.6 KFY00233.1 - 0.036 14.2 2.4 0.058 13.6 2.4 1.3 1 0 0 1 1 1 0 Prokaryotic RING finger family 2 zf-piccolo PF05715.13 KFY00233.1 - 0.077 13.1 3.7 0.13 12.4 3.7 1.4 1 0 0 1 1 1 0 Piccolo Zn-finger FYVE_2 PF02318.16 KFY00233.1 - 0.3 11.3 3.1 0.51 10.6 3.1 1.3 1 0 0 1 1 1 0 FYVE-type zinc finger zf-B_box PF00643.24 KFY00233.1 - 0.44 10.7 7.9 1.2 9.4 7.9 1.7 1 1 0 1 1 1 0 B-box zinc finger APH PF01636.23 KFY00234.1 - 1e-06 28.8 0.0 2.4e-06 27.7 0.0 1.5 2 0 0 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KFY00234.1 - 0.00092 18.9 0.0 0.0018 17.9 0.0 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase DUF4238 PF14022.6 KFY00234.1 - 0.13 11.7 0.0 0.19 11.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4238) Ribo_biogen_C PF04034.13 KFY00236.1 - 1e-49 167.5 0.0 1.4e-49 167.1 0.0 1.2 1 0 0 1 1 1 1 Ribosome biogenesis protein, C-terminal RLI PF04068.15 KFY00236.1 - 4.5e-12 45.6 0.7 9.8e-12 44.5 0.7 1.6 1 0 0 1 1 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI BUD22 PF09073.10 KFY00236.1 - 6.1 6.1 14.7 8.8 5.5 14.7 1.2 1 0 0 1 1 1 0 BUD22 VHS PF00790.19 KFY00237.1 - 3.7e-45 153.2 0.0 1.5e-44 151.3 0.0 2.0 2 0 0 2 2 2 1 VHS domain Alpha_adaptinC2 PF02883.20 KFY00237.1 - 2.7e-20 72.7 0.1 2.7e-20 72.7 0.1 1.8 2 0 0 2 2 2 1 Adaptin C-terminal domain GAT PF03127.14 KFY00237.1 - 1.3e-19 70.3 0.4 1.3e-19 70.3 0.4 2.1 2 0 0 2 2 2 1 GAT domain GGA_N-GAT PF18308.1 KFY00237.1 - 2.6e-07 30.1 0.1 9.8e-07 28.3 0.1 2.0 1 0 0 1 1 1 1 GGA N-GAT domain GTP_EFTU PF00009.27 KFY00239.1 - 3.6e-32 111.5 8.8 5.2e-32 111.0 3.3 2.9 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain IF-2 PF11987.8 KFY00239.1 - 2.4e-26 91.9 0.3 1.1e-25 89.8 0.2 2.2 2 0 0 2 2 2 1 Translation-initiation factor 2 MMR_HSR1 PF01926.23 KFY00239.1 - 9.6e-09 35.3 0.5 3e-08 33.7 0.1 2.1 2 0 0 2 2 2 1 50S ribosome-binding GTPase IF2_N PF04760.15 KFY00239.1 - 4.8e-06 26.3 0.0 1.1e-05 25.2 0.0 1.6 1 0 0 1 1 1 1 Translation initiation factor IF-2, N-terminal region RsgA_GTPase PF03193.16 KFY00239.1 - 1.6e-05 24.9 0.5 0.00024 21.0 0.1 2.5 1 1 1 2 2 2 1 RsgA GTPase Arf PF00025.21 KFY00239.1 - 0.0012 18.3 0.5 0.0024 17.3 0.0 1.7 2 0 0 2 2 2 1 ADP-ribosylation factor family GTP_EFTU_D2 PF03144.25 KFY00239.1 - 0.0044 17.4 5.3 0.029 14.7 0.2 3.6 3 1 0 3 3 2 1 Elongation factor Tu domain 2 SRPRB PF09439.10 KFY00239.1 - 0.011 15.2 0.0 0.029 13.8 0.0 1.8 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit FeoB_N PF02421.18 KFY00239.1 - 0.016 14.7 0.3 0.055 13.0 0.3 1.9 1 1 0 1 1 1 0 Ferrous iron transport protein B PduV-EutP PF10662.9 KFY00239.1 - 0.018 14.8 0.3 0.08 12.7 0.3 2.0 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation MMR_HSR1_Xtn PF16897.5 KFY00239.1 - 0.036 14.1 0.1 0.092 12.8 0.1 1.6 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain DUF1654 PF07867.11 KFY00239.1 - 0.066 13.0 0.5 0.23 11.2 0.5 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF1654) Roc PF08477.13 KFY00239.1 - 0.099 12.9 0.0 0.21 11.8 0.0 1.6 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase GTP_EFTU_D4 PF14578.6 KFY00239.1 - 1.4 8.9 5.7 0.86 9.5 0.8 2.7 3 0 0 3 3 3 0 Elongation factor Tu domain 4 zinc_ribbon_9 PF14369.6 KFY00240.1 - 0.23 11.8 4.9 1.3 9.3 0.2 2.4 2 0 0 2 2 2 0 zinc-ribbon OrfB_Zn_ribbon PF07282.11 KFY00240.1 - 2.7 8.0 4.6 9.8 6.2 4.2 2.1 1 1 0 1 1 1 0 Putative transposase DNA-binding domain ATXN-1_C PF12547.8 KFY00240.1 - 3.8 7.9 10.1 2.6 8.5 7.4 2.2 2 1 0 2 2 2 0 Capicua transcriptional repressor modulator ASF1_hist_chap PF04729.13 KFY00241.1 - 8.2e-69 230.4 0.0 1.4e-68 229.7 0.0 1.4 1 0 0 1 1 1 1 ASF1 like histone chaperone Ras PF00071.22 KFY00245.1 - 3.4e-36 124.3 0.0 2.2e-22 79.4 0.0 2.2 2 0 0 2 2 2 2 Ras family Roc PF08477.13 KFY00245.1 - 1.5e-10 41.4 0.0 3.9e-10 40.0 0.0 1.7 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 KFY00245.1 - 0.00086 19.4 0.0 0.0031 17.6 0.0 1.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase Arf PF00025.21 KFY00245.1 - 0.0016 17.9 0.0 0.0067 15.9 0.0 1.8 2 0 0 2 2 2 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KFY00245.1 - 0.047 13.2 2.4 0.28 10.7 0.1 3.0 2 2 0 3 3 3 0 Elongation factor Tu GTP binding domain AAA_25 PF13481.6 KFY00245.1 - 0.15 11.6 0.0 0.15 11.6 0.0 2.6 3 0 0 3 3 3 0 AAA domain AAA_16 PF13191.6 KFY00245.1 - 0.2 12.0 3.3 0.72 10.2 2.7 2.2 1 1 0 1 1 1 0 AAA ATPase domain eIF-3_zeta PF05091.12 KFY00245.1 - 2.7 6.9 6.5 3.6 6.4 6.5 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Lipase_GDSL_2 PF13472.6 KFY00246.1 - 1.4e-22 80.9 0.1 2.7e-22 80.0 0.1 1.5 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 KFY00246.1 - 3.5e-15 56.5 0.0 5.1e-15 56.0 0.0 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase KH_1 PF00013.29 KFY00247.1 - 1.1e-24 86.1 2.2 9.5e-07 28.6 0.2 6.3 6 0 0 6 6 6 6 KH domain SUR7 PF06687.12 KFY00248.1 - 6.6e-33 114.1 2.0 7.1e-33 114.0 2.0 1.0 1 0 0 1 1 1 1 SUR7/PalI family Fig1 PF12351.8 KFY00248.1 - 0.0048 16.9 1.6 0.0078 16.2 1.6 1.4 1 0 0 1 1 1 1 Ca2+ regulator and membrane fusion protein Fig1 DUF373 PF04123.13 KFY00248.1 - 0.079 12.4 4.4 0.11 11.9 4.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF373) DUF2207 PF09972.9 KFY00248.1 - 0.11 11.2 2.5 0.14 10.9 2.5 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF2768 PF10966.8 KFY00248.1 - 2.9 8.4 10.6 7.4 7.1 10.6 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2768) DUF1772 PF08592.11 KFY00248.1 - 3 8.2 11.1 9.9 6.5 11.1 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF1772) F-box PF00646.33 KFY00249.1 - 0.0074 16.1 0.0 0.018 14.9 0.0 1.6 1 0 0 1 1 1 1 F-box domain eIF3g PF12353.8 KFY00251.1 - 5.1e-44 149.7 6.8 8.3e-44 149.0 6.8 1.3 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit G RRM_1 PF00076.22 KFY00251.1 - 4.6e-17 61.6 0.1 7.6e-17 60.9 0.1 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KFY00251.1 - 0.0021 17.9 0.0 0.0062 16.4 0.0 1.8 1 0 0 1 1 1 1 Occluded RNA-recognition motif zf-CCCH_7 PF18586.1 KFY00251.1 - 0.062 13.6 0.2 0.14 12.5 0.2 1.5 1 0 0 1 1 1 0 Chromatin remodeling factor Mit1 C-terminal Zn finger 1 HSP70 PF00012.20 KFY00252.1 - 4.8e-264 877.1 15.3 5.5e-264 876.9 15.3 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 KFY00252.1 - 9.3e-15 54.3 4.7 1.5e-12 47.0 1.4 2.4 2 0 0 2 2 2 2 MreB/Mbl protein FGGY_C PF02782.16 KFY00252.1 - 0.00019 21.2 0.0 0.00047 19.9 0.0 1.7 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain StbA PF06406.11 KFY00252.1 - 0.027 13.7 4.1 0.12 11.6 0.1 2.8 3 1 1 4 4 4 0 StbA protein Big_3_4 PF13754.6 KFY00252.1 - 0.12 12.1 0.0 2 8.2 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function FtsA PF14450.6 KFY00252.1 - 0.13 12.7 7.3 1.4 9.4 0.3 3.9 3 2 0 3 3 3 0 Cell division protein FtsA TarH PF02203.15 KFY00252.1 - 0.18 11.7 3.0 0.47 10.4 2.1 2.0 2 0 0 2 2 2 0 Tar ligand binding domain homologue Toxin-deaminase PF14424.6 KFY00252.1 - 0.46 10.6 2.4 2.5 8.2 0.0 2.5 2 0 0 2 2 2 0 The BURPS668_1122 family of deaminases EcoR124_C PF12008.8 KFY00252.1 - 0.46 10.1 7.7 0.94 9.1 7.7 1.5 1 0 0 1 1 1 0 Type I restriction and modification enzyme - subunit R C terminal DUF4363 PF14276.6 KFY00252.1 - 1.1 9.4 5.6 2.2 8.4 5.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4363) DUF2415 PF10313.9 KFY00253.1 - 2.6e-12 46.5 0.0 4.9e-12 45.6 0.0 1.5 1 0 0 1 1 1 1 Uncharacterised protein domain (DUF2415) N_NLPC_P60 PF12912.7 KFY00253.1 - 0.016 15.6 0.1 0.036 14.4 0.1 1.5 1 0 0 1 1 1 0 NLPC_P60 stabilising domain, N term zf-BED PF02892.15 KFY00254.1 - 0.015 15.3 0.3 0.015 15.3 0.3 2.1 2 0 0 2 2 2 0 BED zinc finger Zn_clus PF00172.18 KFY00254.1 - 0.024 14.7 8.2 0.054 13.6 8.2 1.6 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain HSP70 PF00012.20 KFY00255.1 - 4e-169 563.6 3.0 4e-169 563.6 3.0 1.5 2 0 0 2 2 2 1 Hsp70 protein MreB_Mbl PF06723.13 KFY00255.1 - 2.2e-12 46.4 0.1 1.3e-11 43.9 0.0 1.9 2 0 0 2 2 2 1 MreB/Mbl protein FtsA PF14450.6 KFY00255.1 - 0.034 14.5 0.7 5 7.6 0.0 3.1 2 2 0 2 2 2 0 Cell division protein FtsA Apolipoprotein PF01442.18 KFY00255.1 - 0.071 13.0 14.3 0.53 10.1 8.2 3.2 2 1 0 2 2 2 0 Apolipoprotein A1/A4/E domain BcrAD_BadFG PF01869.20 KFY00255.1 - 0.072 12.6 0.1 0.36 10.3 0.1 2.1 1 1 0 1 1 1 0 BadF/BadG/BcrA/BcrD ATPase family HrpB_C PF08482.10 KFY00255.1 - 0.13 12.7 0.0 0.36 11.3 0.0 1.8 1 0 0 1 1 1 0 ATP-dependent helicase C-terminal Cu-oxidase_3 PF07732.15 KFY00256.1 - 1.3e-44 151.0 12.3 1.4e-41 141.3 0.1 4.2 4 1 0 4 4 4 2 Multicopper oxidase Cu-oxidase_2 PF07731.14 KFY00256.1 - 1.2e-36 125.5 15.0 3.6e-33 114.2 7.4 4.2 3 2 0 3 3 3 2 Multicopper oxidase Cu-oxidase PF00394.22 KFY00256.1 - 1.7e-32 112.7 0.3 9.1e-30 103.9 0.0 2.6 2 0 0 2 2 2 2 Multicopper oxidase MFS_1 PF07690.16 KFY00257.1 - 6.9e-45 153.5 47.7 1.7e-44 152.2 47.7 1.8 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 KFY00257.1 - 3.5e-10 39.0 21.1 5.7e-10 38.3 21.1 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF4728 PF15860.5 KFY00257.1 - 0.025 15.2 0.2 0.025 15.2 0.2 2.8 2 1 0 2 2 2 0 Domain of unknown function (DUF4728) PEP_mutase PF13714.6 KFY00258.1 - 7e-38 130.4 0.2 8.6e-38 130.1 0.2 1.1 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase ICL PF00463.21 KFY00258.1 - 4.8e-18 64.9 0.1 6.7e-18 64.5 0.1 1.1 1 0 0 1 1 1 1 Isocitrate lyase family ketoacyl-synt PF00109.26 KFY00258.1 - 0.074 12.6 0.1 5.3 6.5 0.0 2.2 2 0 0 2 2 2 0 Beta-ketoacyl synthase, N-terminal domain AflR PF08493.10 KFY00259.1 - 2.3e-08 33.9 1.1 2.8e-08 33.6 1.1 1.2 1 0 0 1 1 1 1 Aflatoxin regulatory protein Myb_DNA-binding PF00249.31 KFY00260.1 - 7.1e-28 96.5 12.7 1.1e-11 44.7 1.5 3.3 3 0 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KFY00260.1 - 4e-26 91.0 5.9 3.5e-12 46.4 0.3 3.4 1 1 2 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 KFY00260.1 - 3.7e-05 23.5 0.3 0.073 13.0 0.1 2.6 2 0 0 2 2 2 2 Myb DNA-binding like MADF_DNA_bdg PF10545.9 KFY00260.1 - 0.021 15.1 6.7 0.27 11.6 1.1 3.3 2 1 1 3 3 3 0 Alcohol dehydrogenase transcription factor Myb/SANT-like Rap1_C PF11626.8 KFY00260.1 - 0.035 14.2 0.9 0.85 9.7 0.1 2.6 1 1 1 2 2 2 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain Myb_DNA-bind_2 PF08914.11 KFY00260.1 - 0.27 11.4 1.9 1.8 8.8 0.0 2.8 2 1 1 3 3 3 0 Rap1 Myb domain Beta-lactamase PF00144.24 KFY00261.1 - 1.9e-43 149.0 0.0 2.5e-43 148.6 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase Beta-lactamase2 PF13354.6 KFY00261.1 - 0.0046 16.6 0.0 0.7 9.5 0.0 2.2 2 0 0 2 2 2 2 Beta-lactamase enzyme family Peptidase_S11 PF00768.20 KFY00261.1 - 0.1 12.0 0.1 0.52 9.7 0.0 1.9 2 0 0 2 2 2 0 D-alanyl-D-alanine carboxypeptidase FAD_binding_3 PF01494.19 KFY00262.1 - 5.9e-14 52.1 0.0 3.6e-06 26.5 0.0 3.1 3 0 0 3 3 3 3 FAD binding domain NAD_binding_8 PF13450.6 KFY00262.1 - 3e-05 24.2 0.0 7.3e-05 22.9 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KFY00262.1 - 0.0011 18.2 0.0 0.0018 17.6 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KFY00262.1 - 0.0015 17.7 0.0 0.051 12.6 0.0 2.1 2 0 0 2 2 2 1 Lycopene cyclase protein FAD_binding_2 PF00890.24 KFY00262.1 - 0.0049 16.0 0.0 0.0067 15.6 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain SE PF08491.10 KFY00262.1 - 0.0058 15.7 0.0 0.25 10.4 0.0 2.2 2 0 0 2 2 2 1 Squalene epoxidase DAO PF01266.24 KFY00262.1 - 0.013 15.1 0.0 0.02 14.5 0.0 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase Pyr_redox PF00070.27 KFY00262.1 - 0.043 14.4 0.0 0.11 13.1 0.0 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase A2M_BRD PF07703.14 KFY00262.1 - 0.057 13.8 0.0 0.093 13.1 0.0 1.5 1 1 0 1 1 1 0 Alpha-2-macroglobulin bait region domain TrkA_N PF02254.18 KFY00262.1 - 0.22 11.8 0.1 2.2 8.6 0.0 2.3 2 0 0 2 2 2 0 TrkA-N domain Pyr_redox_3 PF13738.6 KFY00262.1 - 0.3 10.3 0.5 0.57 9.4 0.1 1.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase EthD PF07110.11 KFY00263.1 - 9.1e-14 52.4 0.3 1.2e-13 52.0 0.3 1.2 1 0 0 1 1 1 1 EthD domain MMS1_N PF10433.9 KFY00264.1 - 4.3e-56 190.5 0.0 7.2e-43 146.9 0.0 2.2 1 1 1 2 2 2 2 Mono-functional DNA-alkylating methyl methanesulfonate N-term GTP_EFTU PF00009.27 KFY00264.1 - 4.5e-33 114.4 0.0 1.5e-32 112.7 0.0 1.9 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain IF-2 PF11987.8 KFY00264.1 - 5.5e-19 68.2 0.0 1.3e-18 67.0 0.0 1.7 1 0 0 1 1 1 1 Translation-initiation factor 2 GTP_EFTU_D2 PF03144.25 KFY00264.1 - 1.7e-08 34.7 1.9 7.2e-07 29.5 0.1 3.1 2 0 0 2 2 2 1 Elongation factor Tu domain 2 GTP_EFTU_D4 PF14578.6 KFY00264.1 - 3.4e-07 30.1 0.2 1.2e-06 28.3 0.2 2.0 1 0 0 1 1 1 1 Elongation factor Tu domain 4 MMR_HSR1 PF01926.23 KFY00264.1 - 3.8e-06 27.0 0.1 1.6e-05 24.9 0.0 2.2 2 0 0 2 2 2 1 50S ribosome-binding GTPase Roc PF08477.13 KFY00264.1 - 0.0022 18.2 0.0 0.0075 16.5 0.0 2.0 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase ATP_bind_1 PF03029.17 KFY00264.1 - 0.016 15.0 0.0 0.045 13.5 0.0 1.8 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein RabGAP-TBC PF00566.18 KFY00265.1 - 2.2e-22 79.8 0.0 3.7e-22 79.1 0.0 1.4 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Prefoldin_2 PF01920.20 KFY00265.1 - 0.13 12.2 2.3 0.56 10.2 0.0 2.3 2 0 0 2 2 2 0 Prefoldin subunit O-FucT PF10250.9 KFY00267.1 - 3.2e-10 40.2 0.0 4.1e-09 36.6 0.0 2.2 1 1 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase TPR_19 PF14559.6 KFY00268.1 - 0.00028 21.3 0.4 2 9.0 0.0 5.1 4 1 0 4 4 4 1 Tetratricopeptide repeat TPR_12 PF13424.6 KFY00268.1 - 0.0036 17.6 0.2 2.9 8.2 0.0 4.3 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_10 PF13374.6 KFY00268.1 - 0.029 14.2 4.2 2.4 8.2 0.1 4.8 5 0 0 5 5 5 0 Tetratricopeptide repeat Glyco_hydr_30_2 PF14587.6 KFY00269.1 - 2.2e-13 50.6 3.7 6.6e-10 39.1 0.0 2.7 1 1 1 2 2 2 2 O-Glycosyl hydrolase family 30 Glyco_hydro_30C PF17189.4 KFY00269.1 - 2.7e-11 43.5 5.7 7.6e-11 42.1 5.7 1.9 1 0 0 1 1 1 1 Glycosyl hydrolase family 30 beta sandwich domain Glyco_hydro_59 PF02057.15 KFY00269.1 - 1.9e-09 37.2 0.1 3.2e-09 36.5 0.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 59 Glyco_hydro_30 PF02055.16 KFY00269.1 - 4.4e-07 29.2 0.0 6.5e-07 28.6 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 30 TIM-barrel domain Melibiase_C PF17801.1 KFY00269.1 - 0.044 13.8 0.1 0.14 12.2 0.1 1.9 1 0 0 1 1 1 0 Alpha galactosidase C-terminal beta sandwich domain adh_short PF00106.25 KFY00274.1 - 6.3e-34 117.1 0.0 8.8e-34 116.7 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KFY00274.1 - 3.3e-26 92.3 0.0 4.6e-26 91.8 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KFY00274.1 - 0.0015 18.4 0.1 0.0033 17.4 0.1 1.5 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 KFY00274.1 - 0.0019 17.7 0.0 0.0029 17.1 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family ADH_zinc_N PF00107.26 KFY00274.1 - 0.11 12.4 0.1 0.22 11.5 0.1 1.5 1 0 0 1 1 1 0 Zinc-binding dehydrogenase MFS_1 PF07690.16 KFY00275.1 - 1.9e-32 112.6 27.1 2.8e-32 112.0 27.1 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF3425 PF11905.8 KFY00275.1 - 6e-22 77.9 0.1 1.2e-21 77.0 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) DUF1691 PF07950.11 KFY00275.1 - 0.052 14.3 0.1 0.17 12.6 0.1 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF1691) Fic PF02661.18 KFY00276.1 - 5.9e-06 27.1 0.0 0.00016 22.5 0.0 2.5 2 1 0 2 2 2 1 Fic/DOC family tRNA-synt_1g PF09334.11 KFY00277.1 - 3.8e-96 322.2 0.1 4.1e-95 318.8 0.1 2.0 1 1 0 1 1 1 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.22 KFY00277.1 - 2.9e-24 85.3 4.6 1.4e-10 40.1 0.9 4.0 1 1 2 3 3 3 3 tRNA synthetases class I (I, L, M and V) tRNA-synt_1e PF01406.19 KFY00277.1 - 2.9e-07 30.1 0.0 0.00012 21.6 0.0 2.1 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain Anticodon_1 PF08264.13 KFY00277.1 - 0.05 13.6 0.0 0.098 12.6 0.0 1.4 1 0 0 1 1 1 0 Anticodon-binding domain of tRNA Cu_amine_oxid PF01179.20 KFY00281.1 - 9.5e-133 443.1 0.0 1.2e-132 442.7 0.0 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN3 PF02728.16 KFY00281.1 - 3.9e-18 65.7 0.0 8.2e-18 64.7 0.0 1.5 1 0 0 1 1 1 1 Copper amine oxidase, N3 domain Cu_amine_oxidN2 PF02727.16 KFY00281.1 - 8.3e-14 51.6 0.2 1.6e-13 50.7 0.2 1.5 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain DUF659 PF04937.15 KFY00281.1 - 0.071 13.0 0.0 0.15 11.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF 659) AA_permease_2 PF13520.6 KFY00282.1 - 1.3e-56 192.3 51.0 1.6e-56 192.0 51.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KFY00282.1 - 3e-18 65.7 38.6 4.1e-18 65.3 38.6 1.1 1 0 0 1 1 1 1 Amino acid permease DUF1182 PF06681.13 KFY00282.1 - 6.3 6.3 12.8 0.052 13.2 2.0 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF1182) Sugar_tr PF00083.24 KFY00287.1 - 8.5e-92 308.4 18.2 1.1e-91 308.0 18.2 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KFY00287.1 - 6e-12 45.2 40.6 6.3e-10 38.5 15.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Gal11_ABD1 PF18535.1 KFY00287.1 - 0.17 12.0 0.4 0.41 10.8 0.0 1.8 2 0 0 2 2 2 0 Gal11 activator-binding domain (ABD1) LVIVD PF08309.11 KFY00288.1 - 6.1e-10 38.3 2.6 0.23 10.8 0.0 5.4 5 0 0 5 5 5 4 LVIVD repeat Beta_propel PF09826.9 KFY00288.1 - 0.019 13.9 0.4 0.4 9.5 0.1 2.2 1 1 0 2 2 2 0 Beta propeller domain Abhydrolase_2 PF02230.16 KFY00289.1 - 6.7e-33 114.3 0.0 2.3e-23 83.2 0.0 4.1 4 0 0 4 4 4 2 Phospholipase/Carboxylesterase Abhydrolase_6 PF12697.7 KFY00289.1 - 4e-15 57.0 4.6 1.3e-11 45.5 2.6 2.8 2 0 0 2 2 2 2 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KFY00289.1 - 4.2e-14 52.4 0.0 1.7e-08 34.0 0.0 3.2 2 1 0 3 3 3 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KFY00289.1 - 3.7e-08 33.3 0.1 5.8e-05 22.8 0.1 2.6 3 0 0 3 3 3 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KFY00289.1 - 1.1e-07 31.5 0.0 0.0022 17.5 0.0 4.0 3 1 0 3 3 3 2 Prolyl oligopeptidase family Abhydrolase_3 PF07859.13 KFY00289.1 - 4.3e-05 23.5 0.0 0.017 15.0 0.0 2.8 2 1 0 2 2 2 2 alpha/beta hydrolase fold FSH1 PF03959.13 KFY00289.1 - 0.0042 16.8 0.0 0.015 15.0 0.0 1.8 1 1 0 1 1 1 1 Serine hydrolase (FSH1) AXE1 PF05448.12 KFY00289.1 - 0.033 12.9 0.1 4.6 5.8 0.0 2.5 2 1 0 2 2 2 0 Acetyl xylan esterase (AXE1) F-box-like PF12937.7 KFY00289.1 - 0.17 11.8 2.0 0.2 11.6 0.1 2.3 3 0 0 3 3 3 0 F-box-like gag-asp_proteas PF13975.6 KFY00290.1 - 1.4e-09 38.3 0.0 0.00063 20.3 0.0 3.3 3 0 0 3 3 3 2 gag-polyprotein putative aspartyl protease Asp_protease PF09668.10 KFY00290.1 - 1.7e-05 24.6 0.0 0.024 14.4 0.0 3.2 2 1 1 3 3 3 2 Aspartyl protease Asp_protease_2 PF13650.6 KFY00290.1 - 6.6e-05 23.5 0.0 0.038 14.6 0.0 2.6 2 0 0 2 2 2 2 Aspartyl protease zf-C2H2 PF00096.26 KFY00290.1 - 0.016 15.6 2.8 0.016 15.6 2.8 3.8 3 0 0 3 3 3 0 Zinc finger, C2H2 type IL7 PF01415.16 KFY00290.1 - 3.6 7.6 6.8 1.7 8.7 2.1 2.6 3 0 0 3 3 3 0 Interleukin 7/9 family Esterase PF00756.20 KFY00296.1 - 7.4e-46 156.8 0.0 8.4e-46 156.6 0.0 1.0 1 0 0 1 1 1 1 Putative esterase Esterase_phd PF10503.9 KFY00296.1 - 7.2e-06 25.6 0.0 0.00063 19.3 0.0 2.1 2 0 0 2 2 2 1 Esterase PHB depolymerase Hydrolase_4 PF12146.8 KFY00296.1 - 1.4e-05 24.5 0.0 0.002 17.4 0.0 2.1 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Chlorophyllase2 PF12740.7 KFY00296.1 - 0.0003 19.8 0.0 0.00055 18.9 0.0 1.4 1 1 0 1 1 1 1 Chlorophyllase enzyme Peptidase_S9 PF00326.21 KFY00296.1 - 0.00087 18.8 0.0 0.0015 18.0 0.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Chlorophyllase PF07224.11 KFY00296.1 - 0.0037 16.3 0.0 0.1 11.6 0.0 2.0 2 0 0 2 2 2 1 Chlorophyllase AXE1 PF05448.12 KFY00296.1 - 0.012 14.4 0.0 0.016 13.9 0.0 1.1 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) PGAP1 PF07819.13 KFY00296.1 - 0.044 13.5 0.0 0.062 13.0 0.0 1.2 1 0 0 1 1 1 0 PGAP1-like protein Abhydrolase_2 PF02230.16 KFY00296.1 - 0.077 12.8 0.0 0.14 11.9 0.0 1.4 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase DLH PF01738.18 KFY00296.1 - 0.11 12.0 0.0 0.42 10.1 0.0 1.9 2 0 0 2 2 2 0 Dienelactone hydrolase family PAF-AH_p_II PF03403.13 KFY00296.1 - 0.12 10.9 0.0 0.22 10.0 0.0 1.4 1 0 0 1 1 1 0 Platelet-activating factor acetylhydrolase, isoform II Afi1 PF07792.12 KFY00297.1 - 4.4e-48 163.1 0.7 1.2e-47 161.8 0.7 1.8 1 0 0 1 1 1 1 Docking domain of Afi1 for Arf3 in vesicle trafficking SPA PF08616.10 KFY00297.1 - 1.1e-38 131.6 0.0 2.2e-38 130.7 0.0 1.5 1 0 0 1 1 1 1 Stabilization of polarity axis Avl9 PF09794.9 KFY00297.1 - 9e-09 34.5 0.0 0.0073 15.1 0.0 4.0 3 1 1 4 4 4 2 Transport protein Avl9 Cwf_Cwc_15 PF04889.12 KFY00297.1 - 0.0011 18.8 6.4 0.0021 17.8 6.4 1.5 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein DUF2347 PF09804.9 KFY00297.1 - 0.012 15.2 0.0 0.1 12.2 0.0 2.5 2 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2347) TFIIA PF03153.13 KFY00297.1 - 0.15 12.0 7.8 0.35 10.8 7.8 1.5 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF1168 PF06658.12 KFY00297.1 - 1.8 8.4 10.5 0.25 11.2 5.5 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1168) EF-hand_6 PF13405.6 KFY00298.1 - 7.8e-12 44.1 0.8 5.9e-05 22.7 0.4 2.6 2 1 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.32 KFY00298.1 - 9.9e-11 40.4 1.1 0.00036 19.9 0.1 2.4 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 KFY00298.1 - 1.7e-07 31.6 3.5 2e-06 28.1 0.3 2.1 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 KFY00298.1 - 3.4e-06 26.8 0.1 0.027 14.3 0.0 2.3 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 KFY00298.1 - 6.6e-06 25.4 4.0 0.0085 15.6 0.7 2.4 2 0 0 2 2 2 2 EF hand EF-hand_9 PF14658.6 KFY00298.1 - 2.6e-05 24.5 0.0 0.085 13.2 0.0 2.4 2 0 0 2 2 2 2 EF-hand domain MoeA_C PF03454.15 KFY00298.1 - 0.008 16.3 0.2 0.14 12.4 0.0 2.3 2 0 0 2 2 2 1 MoeA C-terminal region (domain IV) Hamartin PF04388.12 KFY00298.1 - 2.2 6.9 9.3 2.3 6.8 9.3 1.1 1 0 0 1 1 1 0 Hamartin protein Sugar_tr PF00083.24 KFY00300.1 - 5.1e-17 61.9 3.1 6e-17 61.6 3.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter Xpo1 PF08389.12 KFY00301.1 - 5.7e-38 130.3 0.0 2.7e-37 128.1 0.0 2.3 1 0 0 1 1 1 1 Exportin 1-like protein HEAT PF02985.22 KFY00301.1 - 0.025 14.8 0.2 19 5.8 0.0 4.1 4 0 0 4 4 4 0 HEAT repeat DUF3486 PF11985.8 KFY00301.1 - 0.077 13.4 0.0 0.31 11.4 0.0 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3486) TetR_C_33 PF13305.6 KFY00301.1 - 0.13 13.0 1.0 1.2 9.9 0.2 2.9 1 1 1 2 2 2 0 Tetracyclin repressor-like, C-terminal domain Med10 PF09748.9 KFY00302.1 - 2.9e-46 156.3 0.0 3.4e-46 156.1 0.0 1.0 1 0 0 1 1 1 1 Transcription factor subunit Med10 of Mediator complex DUF4972 PF16342.5 KFY00302.1 - 0.0027 17.4 0.0 0.0046 16.6 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4972) DUF3877 PF12993.7 KFY00302.1 - 0.11 12.4 0.0 0.13 12.1 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function, E. rectale Gene description (DUF3877) DUF4451 PF14616.6 KFY00303.1 - 2.4e-24 85.9 0.1 5.7e-24 84.7 0.1 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4451) Zn_clus PF00172.18 KFY00305.1 - 8.4e-06 25.8 9.0 1.4e-05 25.1 9.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain APH PF01636.23 KFY00309.1 - 0.00099 19.1 0.0 0.0056 16.6 0.0 2.0 1 1 0 1 1 1 1 Phosphotransferase enzyme family Abhydrolase_3 PF07859.13 KFY00311.1 - 4.4e-34 118.2 0.0 7e-24 84.8 0.0 2.3 2 0 0 2 2 2 2 alpha/beta hydrolase fold COesterase PF00135.28 KFY00311.1 - 6.1e-05 22.1 0.0 0.0001 21.3 0.0 1.3 1 0 0 1 1 1 1 Carboxylesterase family Mito_carr PF00153.27 KFY00312.1 - 4e-55 183.7 3.9 1e-18 67.1 0.2 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein WD40 PF00400.32 KFY00313.1 - 4.1e-16 59.1 0.2 9.3e-08 32.6 0.2 5.4 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFY00313.1 - 1.5e-09 38.0 0.0 0.13 12.5 0.0 4.9 3 1 1 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain WDCP PF15390.6 KFY00313.1 - 0.01 14.3 0.0 0.015 13.7 0.0 1.1 1 0 0 1 1 1 0 WD repeat and coiled-coil-containing protein family DUF3823 PF12866.7 KFY00313.1 - 0.05 13.9 0.1 0.14 12.5 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3823) N-terminal domain EAF PF09816.9 KFY00313.1 - 0.12 12.8 0.8 0.63 10.5 0.2 2.3 2 1 0 2 2 2 0 RNA polymerase II transcription elongation factor DUF2818 PF10993.8 KFY00314.1 - 0.28 11.8 2.9 1.4 9.6 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2818) Claudin_2 PF13903.6 KFY00314.1 - 2.3 7.9 9.7 0.56 9.9 0.1 2.9 1 1 1 3 3 3 0 PMP-22/EMP/MP20/Claudin tight junction NAD_binding_10 PF13460.6 KFY00315.1 - 2.6e-17 63.3 0.0 4.1e-17 62.7 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 KFY00315.1 - 0.00059 19.5 0.0 0.001 18.7 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family Epimerase PF01370.21 KFY00315.1 - 0.001 18.6 0.0 0.0018 17.8 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family TrkA_N PF02254.18 KFY00315.1 - 0.19 12.0 0.0 0.36 11.1 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain EnY2 PF10163.9 KFY00319.1 - 2e-05 24.9 0.0 2.9e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 Transcription factor e(y)2 Spidroin_MaSp PF11260.8 KFY00319.1 - 0.093 13.0 0.0 0.16 12.2 0.0 1.5 1 1 0 1 1 1 0 Major ampullate spidroin 1 and 2 COX5B PF01215.19 KFY00320.1 - 3.5e-58 194.9 0.0 4.6e-58 194.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Vb Zn-ribbon_8 PF09723.10 KFY00320.1 - 0.066 13.3 0.0 0.13 12.4 0.0 1.5 1 0 0 1 1 1 0 Zinc ribbon domain AAA PF00004.29 KFY00321.1 - 7.3e-97 320.9 0.0 3.9e-47 160.0 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 KFY00321.1 - 1.1e-24 85.9 6.5 2.2e-13 49.8 0.4 2.8 2 0 0 2 2 2 2 AAA+ lid domain CDC48_N PF02359.18 KFY00321.1 - 2.9e-19 69.0 0.3 9.5e-19 67.4 0.3 2.0 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), N-terminal domain RuvB_N PF05496.12 KFY00321.1 - 1.3e-13 51.0 0.0 1.9e-05 24.4 0.0 3.3 3 1 0 3 3 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_2 PF07724.14 KFY00321.1 - 1.5e-13 51.2 0.0 2.6e-07 30.9 0.0 2.8 2 1 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_33 PF13671.6 KFY00321.1 - 6.4e-13 49.1 0.0 1.1e-05 25.7 0.0 3.0 3 0 0 3 3 3 2 AAA domain AAA_16 PF13191.6 KFY00321.1 - 9e-12 45.7 0.0 0.00012 22.6 0.0 4.4 2 2 0 2 2 2 2 AAA ATPase domain AAA_5 PF07728.14 KFY00321.1 - 6.2e-11 42.5 0.4 1.5e-05 25.0 0.1 3.7 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) TIP49 PF06068.13 KFY00321.1 - 4.5e-09 36.0 0.0 0.0017 17.6 0.0 2.6 2 0 0 2 2 2 2 TIP49 P-loop domain AAA_22 PF13401.6 KFY00321.1 - 8.1e-09 35.9 0.5 0.057 13.7 0.0 4.4 2 2 3 5 5 4 2 AAA domain CDC48_2 PF02933.17 KFY00321.1 - 4.8e-08 32.7 0.0 1.1e-07 31.6 0.0 1.6 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), domain 2 Mg_chelatase PF01078.21 KFY00321.1 - 5.8e-07 29.1 0.2 0.037 13.4 0.0 2.5 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.17 KFY00321.1 - 8.6e-07 28.9 0.0 0.046 13.4 0.0 2.7 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_14 PF13173.6 KFY00321.1 - 1.6e-06 28.2 0.0 0.02 15.0 0.0 3.0 4 0 0 4 4 2 2 AAA domain AAA_18 PF13238.6 KFY00321.1 - 1.6e-06 28.7 0.0 0.04 14.5 0.0 2.7 2 0 0 2 2 2 2 AAA domain RNA_helicase PF00910.22 KFY00321.1 - 3e-06 27.6 0.0 0.041 14.3 0.0 2.9 3 0 0 3 3 2 2 RNA helicase ATPase PF06745.13 KFY00321.1 - 3.1e-06 26.7 0.2 0.61 9.4 0.0 3.4 3 0 0 3 3 3 2 KaiC AAA_7 PF12775.7 KFY00321.1 - 3.6e-06 26.6 0.1 0.034 13.7 0.0 3.0 2 2 0 2 2 2 2 P-loop containing dynein motor region Vps4_C PF09336.10 KFY00321.1 - 9e-06 25.6 0.2 5.9e-05 23.0 0.1 2.3 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain DUF815 PF05673.13 KFY00321.1 - 3.8e-05 23.0 0.0 0.017 14.3 0.0 2.7 2 0 0 2 2 2 1 Protein of unknown function (DUF815) Sigma54_activat PF00158.26 KFY00321.1 - 4e-05 23.4 0.0 0.39 10.4 0.0 3.2 2 2 0 2 2 2 2 Sigma-54 interaction domain AAA_28 PF13521.6 KFY00321.1 - 5.1e-05 23.6 0.0 0.34 11.2 0.0 2.8 2 0 0 2 2 2 2 AAA domain PhoH PF02562.16 KFY00321.1 - 6.3e-05 22.5 0.1 0.4 10.1 0.0 2.5 2 0 0 2 2 2 2 PhoH-like protein ABC_tran PF00005.27 KFY00321.1 - 6.9e-05 23.4 0.0 0.33 11.5 0.0 3.3 2 1 0 2 2 2 1 ABC transporter Parvo_NS1 PF01057.17 KFY00321.1 - 8.6e-05 21.8 0.0 0.083 12.0 0.0 2.2 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 AAA_24 PF13479.6 KFY00321.1 - 0.00016 21.5 0.0 0.77 9.4 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.6 KFY00321.1 - 0.00019 21.1 4.7 1.4 8.4 0.1 4.6 3 2 2 5 5 5 1 AAA domain AAA_17 PF13207.6 KFY00321.1 - 0.0003 21.2 0.0 0.88 10.0 0.0 3.1 3 0 0 3 3 2 1 AAA domain Bac_DnaA PF00308.18 KFY00321.1 - 0.00034 20.5 0.0 0.86 9.4 0.0 2.9 3 0 0 3 3 2 2 Bacterial dnaA protein AAA_3 PF07726.11 KFY00321.1 - 0.00058 19.7 0.0 1.4 8.8 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) TsaE PF02367.17 KFY00321.1 - 0.00074 19.5 0.0 0.66 10.0 0.0 2.5 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE ResIII PF04851.15 KFY00321.1 - 0.00077 19.5 0.0 0.13 12.2 0.0 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_11 PF13086.6 KFY00321.1 - 0.00087 19.2 0.0 1.4 8.6 0.0 2.5 2 0 0 2 2 2 2 AAA domain DUF2075 PF09848.9 KFY00321.1 - 0.0016 17.8 0.0 0.69 9.1 0.0 2.3 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) AAA_30 PF13604.6 KFY00321.1 - 0.0023 17.7 0.3 2.5 7.8 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.6 KFY00321.1 - 0.006 16.9 0.6 9.3 6.6 0.0 3.4 3 1 1 4 4 2 0 AAA domain ATPase_2 PF01637.18 KFY00321.1 - 0.0064 16.4 0.0 10 5.9 0.0 3.5 3 1 0 3 3 3 0 ATPase domain predominantly from Archaea Sigma54_activ_2 PF14532.6 KFY00321.1 - 0.0084 16.2 0.0 1.4 9.0 0.0 2.6 2 0 0 2 2 2 1 Sigma-54 interaction domain NACHT PF05729.12 KFY00321.1 - 0.01 15.7 0.1 3 7.7 0.0 2.9 3 0 0 3 3 3 0 NACHT domain Viral_helicase1 PF01443.18 KFY00321.1 - 0.012 15.4 0.0 0.67 9.6 0.0 2.3 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase IPT PF01745.16 KFY00321.1 - 0.016 14.6 0.0 2.3 7.6 0.0 2.3 2 0 0 2 2 2 0 Isopentenyl transferase KAP_NTPase PF07693.14 KFY00321.1 - 0.02 14.1 0.0 0.91 8.7 0.0 2.6 2 1 1 3 3 3 0 KAP family P-loop domain NB-ARC PF00931.22 KFY00321.1 - 0.023 13.9 0.0 1.6 7.8 0.0 2.5 2 0 0 2 2 2 0 NB-ARC domain Zeta_toxin PF06414.12 KFY00321.1 - 0.033 13.5 0.0 7.4 5.8 0.0 2.7 2 0 0 2 2 2 0 Zeta toxin NTPase_1 PF03266.15 KFY00321.1 - 0.037 13.9 2.4 3.3 7.6 0.0 4.1 4 0 0 4 4 4 0 NTPase UFD1 PF03152.14 KFY00321.1 - 0.043 13.3 0.0 0.15 11.5 0.0 1.8 1 1 1 2 2 2 0 Ubiquitin fusion degradation protein UFD1 Cytidylate_kin2 PF13189.6 KFY00321.1 - 0.066 13.3 0.0 3.5 7.7 0.0 2.5 2 0 0 2 2 2 0 Cytidylate kinase-like family Cytidylate_kin PF02224.18 KFY00321.1 - 0.083 12.6 0.0 10 5.8 0.0 2.7 2 0 0 2 2 2 0 Cytidylate kinase Zot PF05707.12 KFY00321.1 - 0.2 11.3 0.0 10 5.7 0.0 2.8 2 1 1 3 3 3 0 Zonular occludens toxin (Zot) AAA_6 PF12774.7 KFY00321.1 - 0.2 10.6 0.0 8.4 5.2 0.0 2.4 2 0 0 2 2 2 0 Hydrolytic ATP binding site of dynein motor region Pilin_N PF07790.11 KFY00323.1 - 0.027 15.4 0.4 0.053 14.4 0.4 1.5 1 0 0 1 1 1 0 Archaeal Type IV pilin, N-terminal ECSCR PF15820.5 KFY00323.1 - 0.083 12.7 0.1 0.18 11.6 0.1 1.5 1 0 0 1 1 1 0 Endothelial cell-specific chemotaxis regulator PAN_1 PF00024.26 KFY00323.1 - 0.095 12.7 0.0 0.18 11.8 0.0 1.4 1 0 0 1 1 1 0 PAN domain DUF4834 PF16118.5 KFY00323.1 - 0.14 13.1 0.0 0.43 11.6 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) DUF3500 PF12006.8 KFY00324.1 - 8.9e-103 343.8 0.0 1.1e-102 343.5 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3500) FAD_binding_3 PF01494.19 KFY00325.1 - 2.1e-21 76.6 0.1 2.6e-12 46.7 0.0 2.0 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 KFY00325.1 - 2.4e-08 34.1 0.4 6.6e-08 32.7 0.4 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KFY00325.1 - 4.6e-05 22.8 0.2 0.002 17.4 0.6 2.3 2 1 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KFY00325.1 - 8.4e-05 22.3 0.7 0.00085 19.0 0.5 2.1 1 1 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KFY00325.1 - 0.0015 17.7 2.7 0.0034 16.5 2.6 1.6 1 1 1 2 2 2 1 FAD binding domain Thi4 PF01946.17 KFY00325.1 - 0.0036 16.6 0.6 0.0056 15.9 0.2 1.5 2 0 0 2 2 2 1 Thi4 family Pyr_redox_3 PF13738.6 KFY00325.1 - 0.0053 16.1 0.5 0.0094 15.2 0.5 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 KFY00325.1 - 0.0093 14.9 0.2 0.016 14.0 0.2 1.4 1 0 0 1 1 1 1 Tryptophan halogenase ThiF PF00899.21 KFY00325.1 - 0.017 14.5 0.3 0.025 13.9 0.3 1.3 1 0 0 1 1 1 0 ThiF family Pyr_redox PF00070.27 KFY00325.1 - 0.029 14.9 0.2 0.081 13.5 0.2 1.8 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.20 KFY00325.1 - 0.061 13.4 0.2 0.17 12.0 0.2 1.7 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase GIDA PF01134.22 KFY00325.1 - 0.09 11.8 2.0 0.077 12.1 0.8 1.4 2 0 0 2 2 2 0 Glucose inhibited division protein A UDPG_MGDP_dh_N PF03721.14 KFY00325.1 - 0.093 12.3 0.2 0.18 11.4 0.2 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain HI0933_like PF03486.14 KFY00325.1 - 0.11 11.1 0.4 0.17 10.5 0.4 1.2 1 0 0 1 1 1 0 HI0933-like protein MFS_1 PF07690.16 KFY00326.1 - 3.3e-40 138.1 22.2 3.3e-40 138.1 22.2 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KFY00326.1 - 1.7e-09 37.0 21.1 2.2e-09 36.7 5.1 3.1 3 0 0 3 3 3 2 Sugar (and other) transporter TRI12 PF06609.13 KFY00326.1 - 3e-08 32.6 6.1 2.5e-07 29.5 2.0 2.2 2 0 0 2 2 2 2 Fungal trichothecene efflux pump (TRI12) MFS_2 PF13347.6 KFY00326.1 - 0.0013 17.3 3.0 0.0013 17.3 3.0 2.5 2 2 0 2 2 2 1 MFS/sugar transport protein PUCC PF03209.15 KFY00326.1 - 0.0055 15.8 1.1 0.38 9.7 0.7 2.2 2 0 0 2 2 2 2 PUCC protein DUF1361 PF07099.11 KFY00326.1 - 0.066 13.2 2.5 0.083 12.9 0.5 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1361) BT1 PF03092.16 KFY00326.1 - 0.089 11.0 3.8 1.4 7.0 0.2 3.2 3 0 0 3 3 3 0 BT1 family zf-C2H2 PF00096.26 KFY00327.1 - 4.2e-08 33.2 12.1 3.4e-05 24.1 0.1 3.1 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFY00327.1 - 1.6e-05 25.3 10.0 0.025 15.4 0.1 2.9 2 0 0 2 2 2 2 C2H2-type zinc finger Fungal_trans PF04082.18 KFY00327.1 - 4.2e-05 22.7 0.0 6.5e-05 22.1 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-H2C2_2 PF13465.6 KFY00327.1 - 4.7e-05 23.6 17.2 0.00071 19.9 3.6 3.6 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_6 PF13912.6 KFY00327.1 - 6.3e-05 22.9 8.9 0.085 12.9 6.1 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFY00327.1 - 0.00011 22.4 0.7 0.1 12.9 0.5 2.6 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KFY00327.1 - 0.057 13.8 0.3 10 6.7 0.0 2.7 2 0 0 2 2 2 0 Zinc-finger of C2H2 type LIM PF00412.22 KFY00327.1 - 0.19 12.0 3.0 0.53 10.5 3.0 1.7 1 1 0 1 1 1 0 LIM domain zf-C2H2_11 PF16622.5 KFY00327.1 - 1 9.2 0.1 1 9.2 0.1 2.5 2 0 0 2 2 2 0 zinc-finger C2H2-type zf-BED PF02892.15 KFY00327.1 - 1.4 9.0 4.7 3.8 7.6 4.7 1.8 1 0 0 1 1 1 0 BED zinc finger zf-LYAR PF08790.11 KFY00327.1 - 2.2 8.3 5.0 19 5.2 0.0 2.4 2 0 0 2 2 2 0 LYAR-type C2HC zinc finger C1_4 PF07975.12 KFY00327.1 - 4.2 7.7 5.5 1.2 9.5 2.3 1.7 2 0 0 2 2 2 0 TFIIH C1-like domain Peptidase_C15 PF01470.17 KFY00329.1 - 0.013 15.7 0.0 0.015 15.4 0.0 1.1 1 0 0 1 1 1 0 Pyroglutamyl peptidase Glyco_trans_4_2 PF13477.6 KFY00329.1 - 0.036 14.1 0.0 0.038 14.0 0.0 1.2 1 0 0 1 1 1 0 Glycosyl transferase 4-like B12-binding PF02310.19 KFY00329.1 - 0.099 12.7 0.0 3.7 7.6 0.0 2.0 1 1 0 2 2 2 0 B12 binding domain FAA_hydrolase PF01557.18 KFY00330.1 - 1.9e-53 181.3 0.0 2.5e-53 181.0 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family Cyanate_lyase PF02560.14 KFY00331.1 - 7.8e-31 105.7 0.0 1.1e-30 105.3 0.0 1.2 1 0 0 1 1 1 1 Cyanate lyase C-terminal domain Sigma70_r4_2 PF08281.12 KFY00331.1 - 0.0027 17.3 0.0 0.009 15.7 0.0 1.8 2 0 0 2 2 2 1 Sigma-70, region 4 HTH_3 PF01381.22 KFY00331.1 - 0.0045 17.0 0.1 0.008 16.2 0.1 1.4 1 0 0 1 1 1 1 Helix-turn-helix HTH_31 PF13560.6 KFY00331.1 - 0.015 15.6 0.1 0.021 15.2 0.1 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain DUF3786 PF12654.7 KFY00331.1 - 0.046 13.3 0.0 0.077 12.6 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3786) Arm PF00514.23 KFY00332.1 - 1.5e-93 304.3 17.3 3.4e-13 49.1 0.1 8.3 8 0 0 8 8 8 8 Armadillo/beta-catenin-like repeat IBB PF01749.20 KFY00332.1 - 1.1e-26 93.1 1.7 1.1e-26 93.1 1.7 2.0 2 0 0 2 2 2 1 Importin beta binding domain Arm_3 PF16186.5 KFY00332.1 - 1.4e-21 75.8 4.5 3.4e-21 74.5 4.5 1.7 1 0 0 1 1 1 1 Atypical Arm repeat HEAT_EZ PF13513.6 KFY00332.1 - 3.4e-20 72.1 10.3 8.1e-08 32.6 0.1 6.4 5 1 1 6 6 6 4 HEAT-like repeat HEAT_2 PF13646.6 KFY00332.1 - 2.8e-19 69.3 1.2 2.4e-08 34.2 0.0 5.7 3 2 3 6 6 6 4 HEAT repeats HEAT PF02985.22 KFY00332.1 - 8.5e-17 59.8 3.3 0.00011 22.2 0.0 7.2 8 0 0 8 8 8 4 HEAT repeat Arm_2 PF04826.13 KFY00332.1 - 3.2e-07 30.1 0.0 0.0098 15.4 0.0 3.7 2 1 2 4 4 4 3 Armadillo-like Adaptin_N PF01602.20 KFY00332.1 - 5.5e-05 21.9 0.0 0.0047 15.5 0.0 2.4 1 1 1 2 2 2 1 Adaptin N terminal region V-ATPase_H_C PF11698.8 KFY00332.1 - 9.2e-05 22.5 0.0 3.2 7.9 0.0 4.5 3 2 2 5 5 5 2 V-ATPase subunit H NopRA1 PF16201.5 KFY00332.1 - 0.014 15.0 0.0 5.4 6.5 0.0 3.7 2 1 0 3 3 3 0 Nucleolar pre-ribosomal-associated protein 1 HEAT_PBS PF03130.16 KFY00332.1 - 0.02 15.5 3.5 2.3 9.1 0.0 4.5 5 0 0 5 5 5 0 PBS lyase HEAT-like repeat Atx10homo_assoc PF09759.9 KFY00332.1 - 0.037 14.0 0.0 21 5.2 0.0 3.2 3 0 0 3 3 3 0 Spinocerebellar ataxia type 10 protein domain RICTOR_V PF14668.6 KFY00332.1 - 0.1 12.9 4.7 4.4 7.6 0.0 4.4 3 2 2 5 5 5 0 Rapamycin-insensitive companion of mTOR, domain 5 POT1PC PF16686.5 KFY00333.1 - 1.5e-33 115.9 1.0 4.3e-33 114.4 0.1 2.3 3 0 0 3 3 3 1 ssDNA-binding domain of telomere protection protein POT1 PF02765.17 KFY00333.1 - 1.4e-10 41.2 0.0 3.3e-10 40.0 0.0 1.6 1 0 0 1 1 1 1 Telomeric single stranded DNA binding POT1/CDC13 SHNi-TPR PF10516.9 KFY00341.1 - 5.2e-12 45.0 0.2 1.3e-11 43.8 0.2 1.6 1 0 0 1 1 1 1 SHNi-TPR DUF3824 PF12868.7 KFY00341.1 - 3.4e-10 40.8 14.0 3.4e-10 40.8 14.0 8.9 4 2 4 8 8 8 3 Domain of unknwon function (DUF3824) RsgA_GTPase PF03193.16 KFY00341.1 - 0.003 17.5 0.1 0.0063 16.4 0.1 1.4 1 0 0 1 1 1 1 RsgA GTPase UPF0113 PF03657.13 KFY00341.1 - 0.14 12.4 0.1 33 4.8 0.0 2.5 2 0 0 2 2 2 0 UPF0113 PUA domain TelA PF05816.11 KFY00341.1 - 0.48 9.4 8.2 0.041 12.9 3.0 1.7 2 0 0 2 2 2 0 Toxic anion resistance protein (TelA) GRAM PF02893.20 KFY00342.1 - 4.2e-32 110.4 1.8 1.5e-20 73.2 0.0 3.5 3 0 0 3 3 3 3 GRAM domain Glyco_transf_28 PF03033.20 KFY00342.1 - 2.1e-28 99.1 0.0 4.5e-28 98.0 0.0 1.6 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain NIF PF03031.18 KFY00342.1 - 2.5e-27 95.6 0.0 8.6e-27 93.8 0.0 1.9 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase PH PF00169.29 KFY00342.1 - 7.4e-13 48.9 0.1 2.4e-12 47.3 0.1 2.0 1 0 0 1 1 1 1 PH domain PTCB-BRCT PF12738.7 KFY00342.1 - 1.2e-05 25.2 0.1 3e-05 23.9 0.1 1.7 1 0 0 1 1 1 1 twin BRCT domain WD40 PF00400.32 KFY00342.1 - 1.9e-05 25.3 3.8 3.2 8.8 0.0 4.9 4 0 0 4 4 4 2 WD domain, G-beta repeat BRCT PF00533.26 KFY00342.1 - 4.1e-05 23.9 0.0 0.0001 22.6 0.0 1.7 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain PH_11 PF15413.6 KFY00342.1 - 0.0006 20.2 0.2 0.0074 16.7 0.2 2.6 1 1 0 1 1 1 1 Pleckstrin homology domain PH_8 PF15409.6 KFY00342.1 - 0.0011 19.2 0.0 0.0036 17.6 0.0 1.9 1 0 0 1 1 1 1 Pleckstrin homology domain RTT107_BRCT_5 PF16770.5 KFY00342.1 - 0.0036 17.1 0.2 0.013 15.3 0.1 2.0 2 0 0 2 2 2 1 Regulator of Ty1 transposition protein 107 BRCT domain PH_6 PF15406.6 KFY00342.1 - 0.0081 16.4 0.0 0.042 14.1 0.0 2.3 2 0 0 2 2 1 1 Pleckstrin homology domain UDPGT PF00201.18 KFY00342.1 - 0.026 13.3 0.0 0.048 12.5 0.0 1.3 1 0 0 1 1 1 0 UDP-glucoronosyl and UDP-glucosyl transferase BRCT_2 PF16589.5 KFY00342.1 - 0.12 12.7 0.0 0.3 11.5 0.0 1.6 1 0 0 1 1 1 0 BRCT domain, a BRCA1 C-terminus domain PPR_2 PF13041.6 KFY00343.1 - 0.049 13.8 0.0 0.099 12.9 0.0 1.5 1 0 0 1 1 1 0 PPR repeat family SNF2_N PF00176.23 KFY00344.1 - 8e-58 195.8 0.0 1.4e-57 195.0 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Rad54_N PF08658.10 KFY00344.1 - 1.5e-56 191.4 0.1 3.2e-56 190.3 0.1 1.6 1 0 0 1 1 1 1 Rad54 N terminal Helicase_C PF00271.31 KFY00344.1 - 1.4e-15 57.6 0.0 5.7e-15 55.6 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KFY00344.1 - 1.2e-08 35.1 0.0 2.4e-08 34.2 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.8 KFY00344.1 - 0.012 14.8 0.0 0.044 13.0 0.0 1.9 1 1 0 1 1 1 0 Class II histone deacetylase complex subunits 2 and 3 SWI2_SNF2 PF18766.1 KFY00344.1 - 0.046 13.4 0.0 0.12 12.0 0.0 1.7 1 1 0 1 1 1 0 SWI2/SNF2 ATPase Mito_carr PF00153.27 KFY00345.1 - 2.4e-48 162.0 6.0 6.9e-20 70.8 0.1 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein Heliorhodopsin PF18761.1 KFY00345.1 - 0.12 11.7 0.0 3.8 6.7 0.0 2.3 2 0 0 2 2 2 0 Heliorhodopsin Erg28 PF03694.13 KFY00347.1 - 1.1e-24 86.9 0.1 1.4e-24 86.6 0.1 1.1 1 0 0 1 1 1 1 Erg28 like protein WSC PF01822.19 KFY00348.1 - 2.4e-07 30.9 3.7 2.4e-07 30.9 3.7 2.2 2 2 0 2 2 2 1 WSC domain Rpn3_C PF08375.11 KFY00350.1 - 1.2e-25 89.7 1.7 3.3e-25 88.3 1.7 1.8 1 0 0 1 1 1 1 Proteasome regulatory subunit C-terminal PCI PF01399.27 KFY00350.1 - 5.7e-20 71.8 0.4 1.4e-19 70.5 0.1 1.9 2 0 0 2 2 2 1 PCI domain TPR_2 PF07719.17 KFY00350.1 - 0.003 17.5 0.2 0.014 15.5 0.2 2.2 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_16 PF13432.6 KFY00350.1 - 0.16 12.7 1.6 0.6 10.8 0.5 2.6 2 1 0 2 2 2 0 Tetratricopeptide repeat UQ_con PF00179.26 KFY00353.1 - 6.5e-19 68.0 0.0 8.4e-19 67.6 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Pantoate_transf PF02548.15 KFY00354.1 - 3.1e-108 361.1 0.3 3.7e-108 360.8 0.3 1.0 1 0 0 1 1 1 1 Ketopantoate hydroxymethyltransferase PEP_mutase PF13714.6 KFY00354.1 - 3e-06 26.9 0.1 5.5e-06 26.0 0.1 1.4 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase DUF4861 PF16153.5 KFY00354.1 - 0.13 11.2 0.0 0.19 10.7 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4861) NanE PF04131.14 KFY00354.1 - 0.24 10.6 2.3 10 5.2 0.0 2.6 3 0 0 3 3 3 0 Putative N-acetylmannosamine-6-phosphate epimerase APG12 PF04110.13 KFY00355.1 - 3e-29 101.3 0.0 5e-29 100.5 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 Atg8 PF02991.16 KFY00355.1 - 0.0032 17.6 0.0 0.005 17.0 0.0 1.3 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like MitMem_reg PF13012.6 KFY00355.1 - 0.14 12.6 0.0 0.18 12.3 0.0 1.3 1 1 0 1 1 1 0 Maintenance of mitochondrial structure and function Peptidase_M24 PF00557.24 KFY00356.1 - 1.7e-50 171.6 0.0 2.4e-50 171.1 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.16 KFY00356.1 - 1.7e-38 131.1 0.0 2.9e-38 130.4 0.0 1.4 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain RuBisCO_large PF00016.20 KFY00356.1 - 0.15 11.2 0.0 0.23 10.6 0.0 1.2 1 0 0 1 1 1 0 Ribulose bisphosphate carboxylase large chain, catalytic domain Dfp1_Him1_M PF08630.10 KFY00357.1 - 7.9e-46 155.4 0.0 1.8e-45 154.2 0.0 1.7 1 0 0 1 1 1 1 Dfp1/Him1, central region zf-DBF PF07535.12 KFY00357.1 - 1e-20 73.6 0.6 1e-20 73.6 0.6 1.7 2 0 0 2 2 2 1 DBF zinc finger PTCB-BRCT PF12738.7 KFY00357.1 - 0.011 15.6 0.0 0.025 14.5 0.0 1.6 1 0 0 1 1 1 0 twin BRCT domain adh_short PF00106.25 KFY00358.1 - 3.6e-28 98.3 0.0 3e-27 95.4 0.0 1.9 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KFY00358.1 - 1.5e-15 57.4 0.0 5e-15 55.7 0.0 1.7 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KFY00358.1 - 4.2e-08 33.3 0.0 6.6e-08 32.7 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KFY00358.1 - 2.5e-06 27.2 0.0 3.6e-06 26.6 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KFY00358.1 - 0.028 13.8 0.0 0.042 13.3 0.0 1.2 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 KFY00358.1 - 0.04 13.1 0.0 0.055 12.6 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Ribosomal_S2 PF00318.20 KFY00360.1 - 1.3e-65 220.6 0.0 5.1e-65 218.7 0.0 2.1 3 0 0 3 3 3 1 Ribosomal protein S2 CBS PF00571.28 KFY00360.1 - 1.1e-32 112.3 8.7 8.1e-09 35.8 0.0 5.0 5 0 0 5 5 5 4 CBS domain PB1 PF00564.24 KFY00360.1 - 3.8e-10 39.6 0.0 1.2e-09 37.9 0.0 1.9 1 0 0 1 1 1 1 PB1 domain zf-C2H2 PF00096.26 KFY00361.1 - 3.9e-06 27.0 28.1 0.00092 19.5 7.6 4.8 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KFY00361.1 - 1e-05 25.7 18.4 0.00097 19.5 2.7 4.4 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 KFY00361.1 - 0.00028 21.5 24.5 0.016 16.0 6.8 4.6 4 0 0 4 4 4 3 C2H2-type zinc finger AT_hook PF02178.19 KFY00361.1 - 1.4 9.1 4.0 3.9 7.7 4.0 1.8 1 0 0 1 1 1 0 AT hook motif zf-C2H2_11 PF16622.5 KFY00361.1 - 8.8 6.2 16.4 0.63 9.9 4.6 2.9 3 0 0 3 3 3 0 zinc-finger C2H2-type DUF485 PF04341.12 KFY00365.1 - 0.14 12.1 0.1 0.29 11.1 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF485 Nup188_C PF18378.1 KFY00371.1 - 1.4e-123 412.4 0.3 2.3e-123 411.7 0.3 1.3 1 0 0 1 1 1 1 Nuclear pore protein NUP188 C-terminal domain Nup188 PF10487.9 KFY00371.1 - 3.7e-79 266.8 0.0 5.8e-78 262.8 0.0 2.6 1 1 0 1 1 1 1 Nucleoporin subcomplex protein binding to Pom34 DUF1754 PF08555.10 KFY00371.1 - 6.5e-05 23.7 4.1 0.00015 22.5 4.1 1.6 1 0 0 1 1 1 1 Eukaryotic family of unknown function (DUF1754) IGPS PF00218.21 KFY00372.1 - 1.7e-92 309.2 0.0 2.7e-92 308.5 0.0 1.3 1 0 0 1 1 1 1 Indole-3-glycerol phosphate synthase PRAI PF00697.22 KFY00372.1 - 1.8e-53 181.3 0.5 2e-49 168.0 0.0 3.0 2 1 1 3 3 3 2 N-(5'phosphoribosyl)anthranilate (PRA) isomerase GATase PF00117.28 KFY00372.1 - 7.4e-47 159.6 0.0 1.2e-46 158.8 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 KFY00372.1 - 0.0003 20.6 0.8 0.0014 18.4 0.3 2.3 2 1 0 2 2 2 1 Peptidase C26 QRPTase_C PF01729.19 KFY00372.1 - 0.022 14.6 1.9 0.29 10.9 0.1 2.8 3 0 0 3 3 3 0 Quinolinate phosphoribosyl transferase, C-terminal domain His_biosynth PF00977.21 KFY00372.1 - 0.049 13.1 0.1 0.16 11.4 0.0 1.9 2 0 0 2 2 2 0 Histidine biosynthesis protein NanE PF04131.14 KFY00372.1 - 0.063 12.5 0.1 0.33 10.1 0.0 2.0 2 0 0 2 2 2 0 Putative N-acetylmannosamine-6-phosphate epimerase Peripla_BP_2 PF01497.18 KFY00372.1 - 0.086 12.4 0.0 0.25 10.8 0.0 1.7 2 0 0 2 2 2 0 Periplasmic binding protein BRCT PF00533.26 KFY00373.1 - 3.4e-07 30.6 0.0 7.5e-07 29.4 0.0 1.6 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 KFY00373.1 - 0.00052 20.4 0.0 0.00096 19.5 0.0 1.4 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain Nop16 PF09420.10 KFY00373.1 - 0.034 14.2 0.0 0.055 13.5 0.0 1.3 1 0 0 1 1 1 0 Ribosome biogenesis protein Nop16 Rad17 PF03215.15 KFY00386.1 - 3.2e-27 95.6 0.0 9.3e-27 94.2 0.0 1.8 1 1 0 1 1 1 1 Rad17 P-loop domain AAA PF00004.29 KFY00386.1 - 0.00042 20.7 0.2 0.0019 18.6 0.1 2.0 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KFY00386.1 - 0.00069 19.9 0.0 0.0016 18.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KFY00386.1 - 0.0021 18.4 0.2 0.0057 17.1 0.2 1.9 1 1 0 1 1 1 1 AAA ATPase domain TsaE PF02367.17 KFY00386.1 - 0.0024 17.9 0.1 0.0069 16.4 0.1 1.7 2 0 0 2 2 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_30 PF13604.6 KFY00386.1 - 0.0043 16.8 0.2 0.011 15.5 0.2 1.6 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.14 KFY00386.1 - 0.014 15.4 0.1 0.037 14.0 0.1 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_19 PF13245.6 KFY00386.1 - 0.022 15.1 0.1 0.058 13.7 0.1 1.7 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 KFY00386.1 - 0.024 15.2 0.0 0.05 14.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_6 PF12774.7 KFY00386.1 - 0.035 13.1 0.1 0.053 12.5 0.1 1.1 1 0 0 1 1 1 0 Hydrolytic ATP binding site of dynein motor region DUF853 PF05872.12 KFY00386.1 - 0.054 12.1 1.3 0.16 10.6 0.4 2.0 2 1 0 3 3 3 0 Bacterial protein of unknown function (DUF853) AAA_28 PF13521.6 KFY00386.1 - 0.062 13.5 0.0 0.14 12.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain RuvB_N PF05496.12 KFY00386.1 - 0.069 12.9 0.0 0.13 12.0 0.0 1.5 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_33 PF13671.6 KFY00386.1 - 0.13 12.5 0.0 0.25 11.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 KFY00386.1 - 0.13 12.1 0.4 0.27 11.1 0.4 1.5 1 0 0 1 1 1 0 NACHT domain RNA_helicase PF00910.22 KFY00386.1 - 0.21 12.0 0.0 0.42 11.0 0.0 1.5 1 0 0 1 1 1 0 RNA helicase p450 PF00067.22 KFY00387.1 - 4.1e-44 151.1 0.0 3.6e-43 148.0 0.0 2.0 1 1 0 1 1 1 1 Cytochrome P450 Pro-kuma_activ PF09286.11 KFY00388.1 - 5.1e-34 117.6 0.0 8.7e-34 116.8 0.0 1.4 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.22 KFY00388.1 - 2.3e-07 30.4 0.0 5.9e-07 29.0 0.0 1.6 1 0 0 1 1 1 1 Subtilase family FA_desaturase PF00487.24 KFY00389.1 - 1.1e-30 107.3 22.2 1.7e-30 106.7 22.2 1.2 1 0 0 1 1 1 1 Fatty acid desaturase DUF3821 PF12863.7 KFY00389.1 - 0.14 12.0 0.1 0.25 11.2 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3821) EST1_DNA_bind PF10373.9 KFY00398.1 - 7.4e-06 25.6 0.3 2.7e-05 23.8 0.1 2.0 2 1 0 2 2 2 1 Est1 DNA/RNA binding domain RIC3 PF15361.6 KFY00399.1 - 0.024 15.0 0.5 0.048 14.1 0.5 1.4 1 0 0 1 1 1 0 Resistance to inhibitors of cholinesterase homologue 3 DUF2101 PF09874.9 KFY00399.1 - 0.12 12.0 4.6 0.18 11.5 4.6 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2101) ATP-synt_F PF01990.17 KFY00405.1 - 1.2e-33 115.3 0.1 1.4e-33 115.1 0.1 1.0 1 0 0 1 1 1 1 ATP synthase (F/14-kDa) subunit AMP-binding_C PF13193.6 KFY00405.1 - 0.14 13.2 0.3 0.4 11.7 0.3 1.9 1 1 0 1 1 1 0 AMP-binding enzyme C-terminal domain E1_DerP2_DerF2 PF02221.15 KFY00406.1 - 8.2e-27 94.3 0.2 9.5e-27 94.0 0.2 1.1 1 0 0 1 1 1 1 ML domain Alph_Pro_TM PF09608.10 KFY00406.1 - 0.0098 15.7 0.0 0.011 15.5 0.0 1.2 1 0 0 1 1 1 1 Putative transmembrane protein (Alph_Pro_TM) NPCBM_assoc PF10633.9 KFY00406.1 - 0.06 13.6 0.1 0.28 11.4 0.0 1.9 2 0 0 2 2 2 0 NPCBM-associated, NEW3 domain of alpha-galactosidase PHD PF00628.29 KFY00407.1 - 5.7e-07 29.3 8.9 1.1e-06 28.4 8.9 1.5 1 0 0 1 1 1 1 PHD-finger Glycos_transf_4 PF00953.21 KFY00408.1 - 6.2e-32 110.8 7.1 6.2e-32 110.8 7.1 1.8 2 0 0 2 2 2 1 Glycosyl transferase family 4 DUF2070 PF09843.9 KFY00408.1 - 0.21 9.9 8.2 0.2 9.9 7.4 1.4 1 1 0 1 1 1 0 Predicted membrane protein (DUF2070) WD40 PF00400.32 KFY00409.1 - 2.3e-10 40.8 5.9 0.00032 21.4 0.1 4.7 4 0 0 4 4 4 3 WD domain, G-beta repeat Ge1_WD40 PF16529.5 KFY00409.1 - 5.8e-05 22.2 0.0 0.39 9.6 0.0 2.8 3 0 0 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein ANAPC4_WD40 PF12894.7 KFY00409.1 - 0.0084 16.4 0.0 2.9 8.3 0.0 3.3 3 0 0 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain Presenilin PF01080.17 KFY00411.1 - 4.4 6.0 10.7 5 5.8 10.7 1.0 1 0 0 1 1 1 0 Presenilin ECM11 PF15463.6 KFY00412.1 - 1.2e-35 123.0 0.2 1.2e-35 123.0 0.2 2.3 2 0 0 2 2 2 1 Extracellular mutant protein 11 KAP_NTPase PF07693.14 KFY00413.1 - 0.0037 16.5 0.0 0.0092 15.3 0.0 1.5 1 1 0 2 2 2 1 KAP family P-loop domain AAA_16 PF13191.6 KFY00413.1 - 0.0038 17.6 0.1 0.009 16.4 0.0 1.8 1 1 1 2 2 2 1 AAA ATPase domain MeaB PF03308.16 KFY00413.1 - 0.004 16.2 0.0 0.0065 15.5 0.0 1.3 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_18 PF13238.6 KFY00413.1 - 0.0062 17.1 0.0 0.02 15.5 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 KFY00413.1 - 0.12 12.6 0.0 0.32 11.1 0.0 1.7 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.27 KFY00413.1 - 0.12 12.9 0.0 0.22 12.0 0.0 1.5 1 0 0 1 1 1 0 ABC transporter SRP54 PF00448.22 KFY00413.1 - 0.13 11.9 0.0 0.18 11.4 0.0 1.2 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain SpoU_methylas_C PF12105.8 KFY00414.1 - 0.12 12.1 0.1 0.26 11.0 0.1 1.5 1 0 0 1 1 1 0 SpoU, rRNA methylase, C-terminal adh_short PF00106.25 KFY00415.1 - 1.1e-86 289.3 13.4 1.7e-45 154.9 1.2 2.9 3 0 0 3 3 3 2 short chain dehydrogenase adh_short_C2 PF13561.6 KFY00415.1 - 4.1e-68 229.4 6.7 1e-35 123.4 0.7 2.5 2 1 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase MaoC_dehydratas PF01575.19 KFY00415.1 - 1.3e-33 115.2 0.0 2.5e-33 114.3 0.0 1.5 1 0 0 1 1 1 1 MaoC like domain KR PF08659.10 KFY00415.1 - 7.3e-27 94.4 7.4 6.5e-14 52.2 0.8 2.9 3 0 0 3 3 3 2 KR domain THF_DHG_CYH_C PF02882.19 KFY00415.1 - 2.1e-06 27.2 0.3 2.4e-05 23.7 0.1 2.3 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain MaoC_dehydrat_N PF13452.6 KFY00415.1 - 9.8e-05 22.5 0.0 0.13 12.4 0.0 2.5 2 0 0 2 2 2 2 N-terminal half of MaoC dehydratase DUF543 PF04418.12 KFY00415.1 - 3.5 7.7 8.4 8.5 6.4 0.9 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF543) AMP-binding PF00501.28 KFY00416.1 - 1e-92 311.0 0.0 1.6e-92 310.4 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KFY00416.1 - 0.0016 19.4 0.1 0.0036 18.2 0.1 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Methyltransf_16 PF10294.9 KFY00418.1 - 1.2e-12 47.9 0.0 2.8e-05 23.9 0.0 2.2 2 0 0 2 2 2 2 Lysine methyltransferase K_channel_TID PF07941.11 KFY00418.1 - 0.79 10.2 8.3 8.7 6.9 1.1 2.5 2 0 0 2 2 2 0 Potassium channel Kv1.4 tandem inactivation domain DUF3292 PF11696.8 KFY00419.1 - 3.9e-246 818.5 0.0 5e-246 818.2 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3292) p450 PF00067.22 KFY00419.1 - 2e-27 96.1 0.0 1.2e-26 93.5 0.0 1.9 1 1 0 1 1 1 1 Cytochrome P450 DUF1481 PF07356.12 KFY00421.1 - 0.062 13.1 0.0 0.11 12.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1481) Ribosomal_L1 PF00687.21 KFY00422.1 - 3e-63 213.3 1.0 3e-63 213.3 1.0 1.6 2 0 0 2 2 2 1 Ribosomal protein L1p/L10e family Carb_anhydrase PF00194.21 KFY00424.1 - 0.13 11.8 0.0 0.19 11.2 0.0 1.2 1 0 0 1 1 1 0 Eukaryotic-type carbonic anhydrase SWI-SNF_Ssr4 PF08549.10 KFY00430.1 - 0.0046 15.7 2.3 0.011 14.4 2.3 1.6 1 1 0 1 1 1 1 Fungal domain of unknown function (DUF1750) ORC6 PF05460.13 KFY00430.1 - 0.039 13.2 0.5 0.034 13.4 0.5 1.1 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) APC_basic PF05956.11 KFY00430.1 - 0.042 13.3 12.1 0.052 13.0 12.1 1.1 1 0 0 1 1 1 0 APC basic domain AAA PF00004.29 KFY00431.1 - 2e-45 154.4 0.7 6.8e-45 152.7 0.0 2.2 3 0 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_ID_OB PF16450.5 KFY00431.1 - 1.3e-10 41.0 0.1 7.6e-10 38.6 0.0 2.1 2 0 0 2 2 2 1 Proteasomal ATPase OB C-terminal domain AAA_5 PF07728.14 KFY00431.1 - 6.8e-09 35.8 0.5 2.2e-08 34.2 0.1 2.1 2 2 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 KFY00431.1 - 4.6e-08 33.4 0.0 9.8e-08 32.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 KFY00431.1 - 1.5e-07 32.0 0.5 3.4e-05 24.3 0.0 2.9 2 2 0 3 3 3 1 AAA ATPase domain DUF815 PF05673.13 KFY00431.1 - 3.5e-06 26.4 0.0 6.7e-06 25.4 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_22 PF13401.6 KFY00431.1 - 3.9e-05 23.9 1.2 0.0088 16.3 0.1 2.7 1 1 1 2 2 2 1 AAA domain RuvB_N PF05496.12 KFY00431.1 - 0.0002 21.1 0.0 0.00058 19.6 0.0 1.8 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain TsaE PF02367.17 KFY00431.1 - 0.00038 20.5 0.0 0.028 14.4 0.0 2.3 1 1 1 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_18 PF13238.6 KFY00431.1 - 0.00046 20.7 0.0 0.0013 19.2 0.0 1.8 2 0 0 2 2 1 1 AAA domain AAA_lid_3 PF17862.1 KFY00431.1 - 0.00058 19.6 0.1 0.0013 18.5 0.1 1.7 1 0 0 1 1 1 1 AAA+ lid domain AAA_7 PF12775.7 KFY00431.1 - 0.00061 19.3 0.1 0.0026 17.3 0.1 1.9 1 1 0 1 1 1 1 P-loop containing dynein motor region AAA_28 PF13521.6 KFY00431.1 - 0.00071 19.8 0.0 0.0016 18.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.6 KFY00431.1 - 0.0014 18.7 0.1 0.0055 16.7 0.0 2.0 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 KFY00431.1 - 0.0017 18.7 0.0 0.004 17.5 0.0 1.6 1 0 0 1 1 1 1 RNA helicase NTPase_1 PF03266.15 KFY00431.1 - 0.004 17.1 0.0 0.015 15.2 0.0 1.9 2 0 0 2 2 2 1 NTPase AAA_30 PF13604.6 KFY00431.1 - 0.0043 16.8 0.1 0.012 15.3 0.1 1.9 1 1 0 1 1 1 1 AAA domain TIP49 PF06068.13 KFY00431.1 - 0.0051 16.1 0.0 0.0095 15.2 0.0 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_3 PF07726.11 KFY00431.1 - 0.0058 16.5 0.0 0.018 14.9 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) NACHT PF05729.12 KFY00431.1 - 0.008 16.1 0.7 0.11 12.4 0.0 2.8 3 1 0 3 3 3 1 NACHT domain Mg_chelatase PF01078.21 KFY00431.1 - 0.008 15.6 0.0 0.018 14.5 0.0 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_33 PF13671.6 KFY00431.1 - 0.0089 16.2 0.0 0.019 15.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 KFY00431.1 - 0.0094 15.7 0.0 0.033 13.9 0.0 1.9 2 0 0 2 2 2 1 IstB-like ATP binding protein TniB PF05621.11 KFY00431.1 - 0.011 15.2 0.0 0.53 9.7 0.0 2.3 2 0 0 2 2 2 0 Bacterial TniB protein AAA_24 PF13479.6 KFY00431.1 - 0.024 14.4 0.2 0.056 13.2 0.2 1.7 1 1 0 1 1 1 0 AAA domain ATPase_2 PF01637.18 KFY00431.1 - 0.034 14.1 1.0 0.26 11.2 0.1 2.6 2 1 0 2 2 2 0 ATPase domain predominantly from Archaea ATPase PF06745.13 KFY00431.1 - 0.038 13.4 0.9 0.56 9.5 0.0 2.5 3 0 0 3 3 3 0 KaiC AAA_11 PF13086.6 KFY00431.1 - 0.038 13.8 0.1 0.13 12.0 0.0 1.9 2 0 0 2 2 2 0 AAA domain Bac_DnaA PF00308.18 KFY00431.1 - 0.042 13.7 0.0 0.08 12.8 0.0 1.5 1 0 0 1 1 1 0 Bacterial dnaA protein Sigma54_activat PF00158.26 KFY00431.1 - 0.079 12.7 0.1 1.4 8.6 0.0 2.5 2 1 0 2 2 2 0 Sigma-54 interaction domain Viral_Hsp90 PF03225.14 KFY00431.1 - 0.079 11.5 0.0 0.13 10.8 0.0 1.2 1 0 0 1 1 1 0 Viral heat shock protein Hsp90 homologue AFG1_ATPase PF03969.16 KFY00431.1 - 0.085 11.7 0.0 0.14 11.0 0.0 1.4 1 0 0 1 1 1 0 AFG1-like ATPase Zeta_toxin PF06414.12 KFY00431.1 - 0.091 12.0 0.1 0.23 10.7 0.0 1.7 2 0 0 2 2 1 0 Zeta toxin AAA_23 PF13476.6 KFY00431.1 - 0.097 13.2 0.3 5.2 7.5 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.6 KFY00431.1 - 0.12 12.7 0.1 0.38 11.1 0.1 1.8 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 KFY00431.1 - 0.12 11.9 1.6 0.27 10.8 0.1 2.1 2 1 1 3 3 3 0 AAA domain cobW PF02492.19 KFY00431.1 - 0.15 11.6 0.0 0.32 10.6 0.0 1.5 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_29 PF13555.6 KFY00431.1 - 0.19 11.5 0.0 0.38 10.5 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain Parvo_NS1 PF01057.17 KFY00431.1 - 0.21 10.7 0.0 0.37 9.8 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 SHMT PF00464.19 KFY00432.1 - 5.9e-207 687.0 0.0 6.8e-207 686.8 0.0 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Aminotran_1_2 PF00155.21 KFY00432.1 - 8e-05 22.0 0.0 0.00019 20.8 0.0 1.5 1 1 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 KFY00432.1 - 0.00082 18.4 0.0 0.0012 17.8 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 KFY00432.1 - 0.015 14.6 0.0 0.025 13.9 0.0 1.5 1 0 0 1 1 1 0 Beta-eliminating lyase Cys_Met_Meta_PP PF01053.20 KFY00432.1 - 0.019 13.5 0.0 0.032 12.8 0.0 1.3 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme Baculo_DNA_bind PF04786.12 KFY00432.1 - 0.085 12.2 0.0 0.15 11.4 0.0 1.3 1 0 0 1 1 1 0 ssDNA binding protein Nop PF01798.18 KFY00433.1 - 1.3e-88 296.4 0.1 2.1e-88 295.7 0.1 1.4 1 0 0 1 1 1 1 snoRNA binding domain, fibrillarin NOP5NT PF08156.13 KFY00433.1 - 4.6e-19 68.6 0.5 4.2e-18 65.5 0.0 2.9 3 0 0 3 3 3 1 NOP5NT (NUC127) domain RNA_polI_A34 PF08208.11 KFY00433.1 - 3 7.9 22.7 6.3 6.8 22.7 1.5 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 RR_TM4-6 PF06459.12 KFY00433.1 - 5.5 6.7 11.8 10 5.8 11.8 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 AAA PF00004.29 KFY00434.1 - 2.1e-38 131.7 0.1 5e-38 130.5 0.0 1.7 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.10 KFY00434.1 - 5.7e-30 103.1 0.1 2e-29 101.4 0.1 2.0 1 0 0 1 1 1 1 Vps4 C terminal oligomerisation domain MIT PF04212.18 KFY00434.1 - 1.8e-23 82.3 4.5 4e-23 81.2 4.5 1.6 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain RuvB_N PF05496.12 KFY00434.1 - 5.1e-07 29.6 0.0 8.2e-07 28.9 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_2 PF07724.14 KFY00434.1 - 1.1e-05 25.7 0.6 0.0062 16.7 0.0 2.7 3 0 0 3 3 2 1 AAA domain (Cdc48 subfamily) AAA_lid_3 PF17862.1 KFY00434.1 - 1.3e-05 24.9 0.0 0.00016 21.4 0.0 2.5 2 0 0 2 2 2 1 AAA+ lid domain AAA_16 PF13191.6 KFY00434.1 - 7.1e-05 23.3 0.1 0.0093 16.4 0.0 2.5 2 1 1 3 3 2 1 AAA ATPase domain AAA_5 PF07728.14 KFY00434.1 - 0.00017 21.6 0.0 0.00072 19.6 0.0 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.17 KFY00434.1 - 0.0002 21.1 0.0 0.00053 19.8 0.0 1.7 2 0 0 2 2 2 1 IstB-like ATP binding protein DUF815 PF05673.13 KFY00434.1 - 0.00029 20.1 0.0 0.001 18.3 0.0 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF815) USP8_dimer PF08969.11 KFY00434.1 - 0.0003 21.0 2.7 0.00062 19.9 2.7 1.5 1 0 0 1 1 1 1 USP8 dimerisation domain AAA_22 PF13401.6 KFY00434.1 - 0.00035 20.9 0.1 0.07 13.4 0.0 3.0 2 1 1 3 3 3 1 AAA domain AAA_33 PF13671.6 KFY00434.1 - 0.00043 20.4 0.0 0.00097 19.3 0.0 1.7 1 1 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 KFY00434.1 - 0.0013 19.0 0.0 0.017 15.5 0.0 2.4 2 0 0 2 2 2 1 RNA helicase TIP49 PF06068.13 KFY00434.1 - 0.0022 17.2 0.0 0.0038 16.5 0.0 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_25 PF13481.6 KFY00434.1 - 0.0046 16.5 0.2 0.64 9.6 0.1 2.4 1 1 1 2 2 2 1 AAA domain AAA_14 PF13173.6 KFY00434.1 - 0.0061 16.6 0.0 0.013 15.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 KFY00434.1 - 0.0085 15.4 0.1 2.2 7.5 0.1 2.6 1 1 1 2 2 2 1 Zeta toxin Mg_chelatase PF01078.21 KFY00434.1 - 0.0096 15.3 0.0 0.024 14.0 0.0 1.6 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_7 PF12775.7 KFY00434.1 - 0.012 15.2 0.1 0.24 10.9 0.0 2.6 2 1 0 2 2 2 0 P-loop containing dynein motor region AAA_18 PF13238.6 KFY00434.1 - 0.012 16.1 0.1 0.042 14.4 0.0 2.0 2 1 0 2 2 2 0 AAA domain AAA_17 PF13207.6 KFY00434.1 - 0.019 15.4 0.8 0.049 14.1 0.0 2.2 2 2 0 2 2 2 0 AAA domain AAA_24 PF13479.6 KFY00434.1 - 0.031 14.0 0.1 0.085 12.6 0.1 1.7 1 1 0 1 1 1 0 AAA domain Sigma54_activat PF00158.26 KFY00434.1 - 0.051 13.3 0.0 0.41 10.3 0.0 2.2 1 1 0 1 1 1 0 Sigma-54 interaction domain ATPase PF06745.13 KFY00434.1 - 0.068 12.5 0.1 8 5.7 0.0 2.5 1 1 1 2 2 2 0 KaiC PhoH PF02562.16 KFY00434.1 - 0.099 12.1 0.0 0.24 10.8 0.0 1.6 1 0 0 1 1 1 0 PhoH-like protein Torsin PF06309.11 KFY00434.1 - 0.12 12.5 0.0 0.24 11.5 0.0 1.4 1 0 0 1 1 1 0 Torsin ATPase_2 PF01637.18 KFY00434.1 - 0.17 11.8 0.9 2.5 7.9 0.0 2.5 2 1 1 3 3 3 0 ATPase domain predominantly from Archaea Prefoldin_2 PF01920.20 KFY00435.1 - 1.5e-21 76.3 10.8 1.8e-21 76.1 10.8 1.1 1 0 0 1 1 1 1 Prefoldin subunit Prefoldin_3 PF13758.6 KFY00435.1 - 0.00043 20.3 4.3 0.00056 19.9 4.3 1.2 1 0 0 1 1 1 1 Prefoldin subunit Rx_N PF18052.1 KFY00435.1 - 0.013 15.7 2.3 0.013 15.7 2.3 2.1 1 1 1 2 2 2 0 Rx N-terminal domain DUF3160 PF11369.8 KFY00435.1 - 0.024 13.1 3.0 0.028 12.9 3.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3160) DivIC PF04977.15 KFY00435.1 - 0.036 13.8 14.0 0.86 9.4 0.5 2.8 2 1 0 2 2 2 0 Septum formation initiator Chibby PF14645.6 KFY00435.1 - 0.06 13.7 0.4 0.12 12.7 0.4 1.7 1 1 0 1 1 1 0 Chibby family Occludin_ELL PF07303.13 KFY00435.1 - 0.069 13.9 2.3 0.1 13.3 1.6 1.6 1 1 1 2 2 2 0 Occludin homology domain Spc7 PF08317.11 KFY00435.1 - 0.11 11.4 11.2 0.13 11.1 11.2 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein Spc24 PF08286.11 KFY00435.1 - 0.11 12.7 10.0 0.091 13.0 2.8 2.0 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 BRE1 PF08647.11 KFY00435.1 - 0.22 11.6 12.0 0.45 10.6 0.9 2.2 2 0 0 2 2 2 0 BRE1 E3 ubiquitin ligase UPF0242 PF06785.11 KFY00435.1 - 0.22 11.6 10.5 0.28 11.3 10.5 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Prefoldin PF02996.17 KFY00435.1 - 0.34 10.8 9.3 0.92 9.4 0.7 2.4 2 1 0 2 2 2 0 Prefoldin subunit TMF_TATA_bd PF12325.8 KFY00435.1 - 0.44 10.8 11.8 2.7 8.2 1.1 2.1 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding Tropomyosin_1 PF12718.7 KFY00435.1 - 0.48 10.6 11.5 0.71 10.0 3.8 2.1 2 0 0 2 2 2 0 Tropomyosin like Tup_N PF08581.10 KFY00435.1 - 0.58 10.5 7.6 3.1 8.2 0.1 3.1 2 1 1 3 3 3 0 Tup N-terminal APG6_N PF17675.1 KFY00435.1 - 0.8 10.2 14.1 0.55 10.8 1.3 2.1 1 1 1 2 2 2 0 Apg6 coiled-coil region Fib_alpha PF08702.10 KFY00435.1 - 0.92 9.7 9.2 3.9 7.7 9.2 1.8 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family DUF5384 PF17358.2 KFY00435.1 - 1.4 9.0 12.2 3.8 7.5 12.2 1.7 1 1 0 1 1 1 0 Family of unknown function (DUF5384) DUF4407 PF14362.6 KFY00435.1 - 1.5 8.1 12.0 1.9 7.8 12.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Uso1_p115_C PF04871.13 KFY00435.1 - 3 8.2 13.1 35 4.8 13.1 2.0 1 1 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region NPV_P10 PF05531.12 KFY00435.1 - 4 8.0 7.8 9.8 6.7 1.5 2.2 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein ABC_tran_CTD PF16326.5 KFY00435.1 - 5.1 7.4 11.6 2.1 8.7 1.2 2.9 2 1 0 2 2 2 0 ABC transporter C-terminal domain Bap31_Bap29_C PF18035.1 KFY00435.1 - 5.6 7.0 8.8 1.9 8.5 4.8 2.4 2 1 0 2 2 2 0 Bap31/Bap29 cytoplasmic coiled-coil domain Ank_2 PF12796.7 KFY00439.1 - 6.5e-87 286.2 0.2 1.2e-17 64.2 0.1 6.9 1 1 5 6 6 6 6 Ankyrin repeats (3 copies) Ank PF00023.30 KFY00439.1 - 4.3e-81 264.1 0.0 1.8e-05 25.0 0.0 13.3 13 0 0 13 13 13 12 Ankyrin repeat Ank_3 PF13606.6 KFY00439.1 - 1.4e-74 237.0 0.0 7.8e-05 22.8 0.0 13.6 13 1 0 13 13 13 12 Ankyrin repeat Ank_4 PF13637.6 KFY00439.1 - 4.5e-70 231.2 1.6 6.8e-08 32.9 0.0 10.4 1 1 13 14 14 14 13 Ankyrin repeats (many copies) Ank_5 PF13857.6 KFY00439.1 - 2.2e-54 180.8 0.1 1e-08 35.3 0.0 11.4 4 2 9 13 13 13 11 Ankyrin repeats (many copies) DUF4350 PF14258.6 KFY00439.1 - 3.3e-09 37.1 9.8 16 6.0 0.0 10.5 10 2 2 12 12 12 2 Domain of unknown function (DUF4350) UDPG_MGDP_dh_C PF03720.15 KFY00439.1 - 3.3e-06 27.5 9.7 32 5.0 0.0 8.9 6 3 5 11 11 11 0 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain Pkinase PF00069.25 KFY00446.1 - 4.8e-67 226.1 0.0 6.7e-67 225.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFY00446.1 - 9.6e-43 146.3 0.0 1.3e-42 145.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KFY00446.1 - 9.5e-10 38.2 0.0 3.4e-09 36.4 0.0 1.7 2 0 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 KFY00446.1 - 1.2e-06 27.7 0.2 1.2e-06 27.7 0.2 2.0 2 0 0 2 2 2 1 Haspin like kinase domain Kdo PF06293.14 KFY00446.1 - 0.027 13.8 0.0 0.066 12.6 0.0 1.6 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KFY00446.1 - 0.16 11.9 7.6 1.2 9.0 0.1 3.6 2 2 2 4 4 4 0 Phosphotransferase enzyme family RIO1 PF01163.22 KFY00446.1 - 0.93 9.1 4.1 0.24 11.0 0.1 2.0 3 0 0 3 3 3 0 RIO1 family zf-C3HC4_3 PF13920.6 KFY00447.1 - 4.7e-06 26.4 7.8 4.7e-06 26.4 7.8 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KFY00447.1 - 1.7e-05 24.6 10.5 1.7e-05 24.6 10.5 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KFY00447.1 - 2e-05 24.8 11.7 2e-05 24.8 11.7 2.5 2 0 0 2 2 2 1 Ring finger domain zf-RING_UBOX PF13445.6 KFY00447.1 - 3.2e-05 23.9 8.9 3.2e-05 23.9 8.9 2.2 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 KFY00447.1 - 5e-05 23.1 11.3 5e-05 23.1 11.3 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 KFY00447.1 - 5.2e-05 23.3 12.5 5.2e-05 23.3 12.5 2.1 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.6 KFY00447.1 - 0.00016 21.5 9.0 0.00016 21.5 9.0 2.6 2 1 0 2 2 2 1 zinc-RING finger domain zinc-ribbons_6 PF07191.12 KFY00447.1 - 0.37 10.8 9.5 0.82 9.7 0.1 2.5 2 0 0 2 2 2 0 zinc-ribbons zinc_ribbon_2 PF13240.6 KFY00447.1 - 0.47 10.2 4.2 7.1 6.5 0.1 3.5 3 0 0 3 3 3 0 zinc-ribbon domain PhnA_Zn_Ribbon PF08274.12 KFY00447.1 - 0.64 10.0 5.4 0.84 9.6 0.1 3.0 3 0 0 3 3 3 0 PhnA Zinc-Ribbon Prok-RING_4 PF14447.6 KFY00447.1 - 2.5 8.0 15.8 0.1 12.5 7.6 2.3 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 UPF0547 PF10571.9 KFY00447.1 - 3.5 7.8 13.0 0.47 10.6 1.4 2.9 3 0 0 3 3 3 0 Uncharacterised protein family UPF0547 zf-RING_10 PF16685.5 KFY00447.1 - 5.2 7.3 12.6 1.3 9.2 7.5 2.2 2 0 0 2 2 2 0 zinc RING finger of MSL2 Response_reg PF00072.24 KFY00461.1 - 4.1e-20 72.0 0.0 2.7e-14 53.3 0.0 2.7 3 0 0 3 3 3 2 Response regulator receiver domain PQ-loop PF04193.14 KFY00462.1 - 2.1e-11 43.4 8.5 3.3e-06 26.8 0.4 3.7 3 1 1 4 4 4 2 PQ loop repeat SNase PF00565.17 KFY00463.1 - 7.6e-68 225.8 0.9 5e-23 81.6 0.0 5.4 5 0 0 5 5 5 5 Staphylococcal nuclease homologue TUDOR PF00567.24 KFY00463.1 - 4.8e-23 81.5 0.0 1.3e-22 80.1 0.0 1.8 1 0 0 1 1 1 1 Tudor domain SMN PF06003.12 KFY00463.1 - 0.00015 21.2 0.0 0.00031 20.1 0.0 1.4 1 0 0 1 1 1 1 Survival motor neuron protein (SMN) Agenet PF05641.12 KFY00463.1 - 0.1 13.1 0.0 0.46 11.0 0.0 2.3 1 0 0 1 1 1 0 Agenet domain DUF4413 PF14372.6 KFY00469.1 - 0.0002 21.7 0.2 0.00046 20.5 0.0 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF4413) Dimer_Tnp_hAT PF05699.14 KFY00469.1 - 0.097 12.5 2.0 0.1 12.4 0.3 1.9 2 0 0 2 2 2 0 hAT family C-terminal dimerisation region EssA PF10661.9 KFY00471.1 - 0.074 12.9 0.1 0.11 12.4 0.1 1.2 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein EssA AAA PF00004.29 KFY00471.1 - 0.084 13.3 0.1 0.75 10.2 0.0 2.1 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA PF00004.29 KFY00473.1 - 0.089 13.2 0.1 0.57 10.6 0.0 2.0 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 KFY00473.1 - 0.14 11.9 0.0 0.23 11.2 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain Tom22 PF04281.13 KFY00479.1 - 7.4e-47 158.6 0.1 8.6e-47 158.4 0.1 1.0 1 0 0 1 1 1 1 Mitochondrial import receptor subunit Tom22 EBV-NA3 PF05009.12 KFY00479.1 - 5.1 6.5 5.4 34 3.9 0.0 2.0 2 0 0 2 2 2 0 Epstein-Barr virus nuclear antigen 3 (EBNA-3) PTCB-BRCT PF12738.7 KFY00480.1 - 5.9e-49 163.9 0.7 8.6e-22 76.9 0.0 3.5 3 0 0 3 3 3 3 twin BRCT domain BRCT PF00533.26 KFY00480.1 - 2.5e-35 120.7 0.8 5.6e-14 52.3 0.0 5.4 5 1 0 5 5 5 3 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 KFY00480.1 - 2.3e-17 63.2 0.0 1.8e-06 28.2 0.0 4.5 4 0 0 4 4 4 4 BRCT domain, a BRCA1 C-terminus domain BRCT_3 PF18428.1 KFY00480.1 - 2.5e-07 30.7 0.1 0.0072 16.4 0.0 4.0 4 0 0 4 4 4 2 BRCA1 C Terminus (BRCT) domain LIG3_BRCT PF16759.5 KFY00480.1 - 3.6e-07 30.4 0.1 0.0066 16.7 0.0 4.1 4 0 0 4 4 4 1 DNA ligase 3 BRCT domain Arrestin_C PF02752.22 KFY00481.1 - 3.5e-08 34.0 0.0 2e-07 31.5 0.0 2.2 1 1 0 1 1 1 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 KFY00481.1 - 8.4e-08 32.4 0.1 0.0031 17.6 0.0 3.5 4 0 0 4 4 4 2 Arrestin (or S-antigen), N-terminal domain CDC45 PF02724.14 KFY00481.1 - 0.37 9.0 0.9 3.9 5.7 0.0 2.0 2 0 0 2 2 2 0 CDC45-like protein Dynamin_N PF00350.23 KFY00482.1 - 2.9e-16 60.0 1.5 5.5e-16 59.1 0.0 2.2 2 1 0 2 2 2 1 Dynamin family MMR_HSR1 PF01926.23 KFY00482.1 - 1.8e-09 37.7 0.0 1e-08 35.2 0.0 2.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 KFY00482.1 - 5.2e-06 26.1 2.6 0.00014 21.5 2.4 2.7 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain DUF2205 PF10224.9 KFY00482.1 - 0.012 15.6 0.0 0.052 13.5 0.0 2.2 1 0 0 1 1 1 0 Short coiled-coil protein IIGP PF05049.13 KFY00482.1 - 0.021 13.9 0.0 0.04 13.0 0.0 1.4 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) TsaE PF02367.17 KFY00482.1 - 0.12 12.4 0.0 0.24 11.4 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE FAM25 PF15825.5 KFY00482.1 - 0.29 11.5 3.2 0.18 12.2 0.9 1.9 2 0 0 2 2 2 0 FAM25 family Snf7 PF03357.21 KFY00483.1 - 2.5e-35 121.6 19.7 2.5e-35 121.6 19.7 1.3 2 0 0 2 2 2 1 Snf7 DUF592 PF04574.13 KFY00483.1 - 0.81 9.4 3.9 8.5 6.1 0.1 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF592) Hpt PF01627.23 KFY00483.1 - 1.5 9.1 5.4 0.42 10.9 1.3 2.2 2 1 0 2 2 2 0 Hpt domain PP2C PF00481.21 KFY00484.1 - 2.8e-62 210.7 0.8 1.2e-50 172.6 0.4 3.1 3 0 0 3 3 3 2 Protein phosphatase 2C DUF4211 PF13926.6 KFY00485.1 - 1e-40 139.1 0.0 3.5e-40 137.4 0.0 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4211) CENP-B_dimeris PF09026.10 KFY00485.1 - 0.07 13.5 0.5 0.07 13.5 0.5 3.5 3 0 0 3 3 3 0 Centromere protein B dimerisation domain CaM_bdg_C0 PF10562.9 KFY00485.1 - 0.68 10.0 6.6 2.2 8.4 6.6 1.9 1 0 0 1 1 1 0 Calmodulin-binding domain C0 of NMDA receptor NR1 subunit DUF4449 PF14613.6 KFY00486.1 - 2.8e-66 222.7 1.7 2.8e-66 222.7 1.7 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF4449) Prp18 PF02840.15 KFY00486.1 - 0.09 12.8 1.3 2.5 8.1 0.0 2.8 1 1 1 2 2 2 0 Prp18 domain RasGEF PF00617.19 KFY00488.1 - 2.4e-59 200.5 0.0 3.9e-59 199.8 0.0 1.4 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 KFY00488.1 - 1e-27 96.4 0.3 2.2e-27 95.4 0.3 1.6 1 0 0 1 1 1 1 RasGEF N-terminal motif SH3_1 PF00018.28 KFY00488.1 - 1.9e-15 56.2 0.1 3.8e-15 55.2 0.1 1.6 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KFY00488.1 - 4.6e-14 52.0 0.2 8.8e-14 51.1 0.2 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 KFY00488.1 - 3.2e-13 49.1 0.1 6e-13 48.3 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain WW PF00397.26 KFY00488.1 - 8.9e-05 22.5 0.0 0.00018 21.5 0.0 1.5 1 0 0 1 1 1 1 WW domain DUF5333 PF17267.2 KFY00488.1 - 0.012 15.7 0.1 0.52 10.5 0.1 2.5 2 0 0 2 2 2 0 Family of unknown function (DUF5333) SQS_PSY PF00494.19 KFY00488.1 - 0.078 12.5 0.0 0.17 11.4 0.0 1.5 1 0 0 1 1 1 0 Squalene/phytoene synthase Ubie_methyltran PF01209.18 KFY00490.1 - 3.9e-20 72.2 0.0 5.9e-20 71.6 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Glyco_transf_90 PF05686.12 KFY00490.1 - 0.014 14.3 0.0 0.017 14.1 0.0 1.0 1 0 0 1 1 1 0 Glycosyl transferase family 90 E1_dh PF00676.20 KFY00491.1 - 5.7e-84 281.6 0.0 7.1e-84 281.3 0.0 1.1 1 0 0 1 1 1 1 Dehydrogenase E1 component TPP_enzyme_C PF02775.21 KFY00491.1 - 0.00019 21.3 0.1 0.0015 18.4 0.0 2.3 2 1 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain XFP_N PF09364.10 KFY00491.1 - 0.18 10.6 0.0 0.28 10.0 0.0 1.3 1 0 0 1 1 1 0 XFP N-terminal domain DUF1771 PF08590.10 KFY00492.1 - 6.6e-08 32.8 7.0 1.6e-07 31.5 7.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1771) Smr PF01713.21 KFY00492.1 - 0.00017 21.8 0.8 0.00045 20.5 0.8 1.8 1 0 0 1 1 1 1 Smr domain DMA PF03474.14 KFY00492.1 - 0.00026 20.5 0.0 0.00063 19.3 0.0 1.6 1 0 0 1 1 1 1 DMRTA motif CUE PF02845.16 KFY00492.1 - 0.0023 17.6 0.0 0.0052 16.5 0.0 1.6 1 0 0 1 1 1 1 CUE domain DUF1685 PF07939.11 KFY00492.1 - 0.19 11.5 0.3 10 5.9 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF1685) HECT PF00632.25 KFY00493.1 - 1e-75 255.1 0.0 1.9e-75 254.2 0.0 1.5 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Arm PF00514.23 KFY00493.1 - 0.28 11.3 6.9 38 4.5 0.2 5.9 6 1 1 7 7 7 0 Armadillo/beta-catenin-like repeat NmrA PF05368.13 KFY00508.1 - 0.00077 19.1 0.0 0.00099 18.7 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KFY00508.1 - 0.0062 16.4 0.0 0.0095 15.8 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding YcaO PF02624.16 KFY00508.1 - 0.18 11.0 0.1 0.4 9.9 0.1 1.5 2 0 0 2 2 2 0 YcaO cyclodehydratase, ATP-ad Mg2+-binding Ank_2 PF12796.7 KFY00510.1 - 2.7e-24 85.5 4.6 2.4e-09 37.6 0.1 4.2 2 1 2 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KFY00510.1 - 1.8e-23 82.5 7.2 3.7e-05 24.2 0.0 7.5 2 2 6 8 8 8 7 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFY00510.1 - 1.7e-19 67.9 6.9 0.00088 19.6 0.0 8.8 9 0 0 9 9 9 4 Ankyrin repeat Ank_5 PF13857.6 KFY00510.1 - 1.9e-15 56.7 6.0 3.1e-05 24.2 0.2 5.6 4 2 0 5 5 5 3 Ankyrin repeats (many copies) Ank PF00023.30 KFY00510.1 - 1.5e-14 53.7 8.4 0.0011 19.3 0.1 8.1 8 0 0 8 8 8 4 Ankyrin repeat pRN1_helical PF13010.6 KFY00510.1 - 0.057 13.4 0.0 0.15 12.0 0.0 1.7 1 0 0 1 1 1 0 Primase helical domain MFS_1 PF07690.16 KFY00512.1 - 3.5e-11 42.6 15.6 4.4e-11 42.3 15.6 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Nodulin-like PF06813.13 KFY00512.1 - 3e-08 33.4 5.0 3.4e-08 33.3 5.0 1.0 1 0 0 1 1 1 1 Nodulin-like Serinc PF03348.15 KFY00513.1 - 2.2e-165 550.7 6.2 2.5e-165 550.6 6.2 1.0 1 0 0 1 1 1 1 Serine incorporator (Serinc) Adipogenin PF15202.6 KFY00513.1 - 0.74 9.9 4.4 22 5.2 0.3 2.9 2 0 0 2 2 2 0 Adipogenin Glyco_hydro_53 PF07745.13 KFY00514.1 - 4.6e-102 341.5 1.9 5.2e-102 341.3 1.9 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 53 Cellulase PF00150.18 KFY00514.1 - 0.00054 19.5 3.3 0.00074 19.0 3.3 1.4 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) DUF4015 PF13200.6 KFY00514.1 - 0.028 13.5 0.6 0.55 9.2 0.1 2.1 1 1 0 2 2 2 0 Putative glycosyl hydrolase domain DUF2722 PF10846.8 KFY00516.1 - 0.7 8.8 3.9 0.95 8.3 3.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) DUF4820 PF16091.5 KFY00516.1 - 1 8.7 3.5 1.8 7.9 3.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) FAM176 PF14851.6 KFY00516.1 - 4.2 7.0 12.7 12 5.6 12.7 1.7 1 0 0 1 1 1 0 FAM176 family Pectinesterase PF01095.19 KFY00517.1 - 6.6e-41 140.0 1.5 9.8e-41 139.4 1.5 1.2 1 0 0 1 1 1 1 Pectinesterase Glycoprotein_B PF00606.18 KFY00517.1 - 0.15 11.5 0.1 0.63 9.4 0.0 1.9 2 0 0 2 2 2 0 Herpesvirus Glycoprotein B ectodomain Pec_lyase_C PF00544.19 KFY00518.1 - 1.9e-13 50.5 6.7 1.8e-11 44.1 6.7 2.5 1 1 0 1 1 1 1 Pectate lyase Beta_helix PF13229.6 KFY00518.1 - 0.00034 20.5 12.7 0.02 14.8 10.7 2.8 1 1 2 3 3 3 3 Right handed beta helix region adh_short PF00106.25 KFY00519.1 - 7.6e-16 58.1 2.3 4e-15 55.8 0.7 2.5 2 1 1 3 3 3 1 short chain dehydrogenase adh_short_C2 PF13561.6 KFY00519.1 - 5.7e-11 42.4 1.1 6.2e-10 39.0 1.1 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KFY00519.1 - 0.00012 22.1 0.7 0.00019 21.4 0.3 1.5 2 0 0 2 2 2 1 KR domain ApbA PF02558.16 KFY00519.1 - 0.00055 19.6 0.2 0.0011 18.6 0.2 1.5 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA 3HCDH_N PF02737.18 KFY00519.1 - 0.0033 17.3 0.7 0.0066 16.3 0.7 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain THF_DHG_CYH_C PF02882.19 KFY00519.1 - 0.0073 15.6 0.1 0.014 14.8 0.1 1.4 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Pyr_redox_3 PF13738.6 KFY00519.1 - 0.016 14.5 0.2 0.027 13.7 0.2 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.6 KFY00519.1 - 0.059 13.8 1.0 0.085 13.3 0.4 1.8 2 1 0 2 2 2 0 Putative NAD(P)-binding Glyco_tran_28_C PF04101.16 KFY00521.1 - 0.15 12.0 0.2 0.55 10.2 0.0 2.0 3 0 0 3 3 3 0 Glycosyltransferase family 28 C-terminal domain CRAL_TRIO PF00650.20 KFY00522.1 - 3.4e-42 143.8 0.0 6.8e-42 142.9 0.0 1.5 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 KFY00522.1 - 8.7e-09 35.4 0.1 4.5e-08 33.2 0.0 2.2 2 0 0 2 2 2 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.6 KFY00522.1 - 5.4e-06 26.6 0.0 1.2e-05 25.5 0.0 1.5 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain DUF3712 PF12505.8 KFY00523.1 - 3.9e-35 120.8 2.3 6.7e-35 120.1 0.2 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF3712) FA_hydroxylase PF04116.13 KFY00524.1 - 5.7e-22 78.5 10.2 5.7e-22 78.5 10.2 2.4 2 1 0 2 2 2 1 Fatty acid hydroxylase superfamily adh_short PF00106.25 KFY00525.1 - 3.1e-35 121.4 0.1 4.1e-35 121.0 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KFY00525.1 - 6e-27 94.7 0.1 8.6e-27 94.2 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KFY00525.1 - 3.8e-05 23.7 3.2 0.0005 20.0 3.2 2.0 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 KFY00525.1 - 0.00012 21.6 0.1 0.00018 21.1 0.1 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family DFP PF04127.15 KFY00525.1 - 0.0022 17.9 0.7 0.0064 16.3 0.1 1.8 1 1 1 2 2 2 1 DNA / pantothenate metabolism flavoprotein RmlD_sub_bind PF04321.17 KFY00525.1 - 0.0044 16.2 0.0 0.0066 15.6 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain UPF0146 PF03686.13 KFY00525.1 - 0.032 14.1 0.0 0.063 13.2 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0146) POR PF01558.18 KFY00525.1 - 0.074 13.1 0.0 0.12 12.4 0.0 1.4 1 0 0 1 1 1 0 Pyruvate ferredoxin/flavodoxin oxidoreductase GCIP PF13324.6 KFY00526.1 - 0.061 12.9 0.3 3.4 7.2 0.0 2.5 2 0 0 2 2 2 0 Grap2 and cyclin-D-interacting FMO-like PF00743.19 KFY00527.1 - 7e-16 57.7 0.0 7.4e-14 51.0 0.0 2.7 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 KFY00527.1 - 5.9e-13 48.7 0.0 2.6e-11 43.4 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KFY00527.1 - 9.1e-12 44.8 0.0 1.8e-08 34.0 0.0 2.5 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KFY00527.1 - 1.1e-09 38.3 0.0 1.2e-07 31.8 0.0 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 KFY00527.1 - 6.9e-08 32.0 0.0 1.7e-05 24.2 0.0 2.4 2 0 0 2 2 2 2 Thi4 family DAO PF01266.24 KFY00527.1 - 1.8e-06 27.8 1.3 0.056 13.0 0.1 4.4 3 2 2 5 5 5 1 FAD dependent oxidoreductase K_oxygenase PF13434.6 KFY00527.1 - 2e-06 27.2 0.0 0.0008 18.6 0.0 2.9 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox PF00070.27 KFY00527.1 - 0.00015 22.2 0.0 0.065 13.8 0.0 2.8 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KFY00527.1 - 0.00039 20.5 0.2 4.1 7.4 0.0 4.0 4 0 0 4 4 4 1 FAD-NAD(P)-binding FAD_binding_2 PF00890.24 KFY00527.1 - 0.006 15.7 0.1 0.29 10.2 0.4 2.7 2 1 1 3 3 3 1 FAD binding domain FAD_binding_3 PF01494.19 KFY00527.1 - 0.0064 15.8 0.0 21 4.2 0.0 3.2 3 0 0 3 3 3 0 FAD binding domain Lycopene_cycl PF05834.12 KFY00527.1 - 0.023 13.7 0.0 15 4.5 0.0 3.6 4 0 0 4 4 4 0 Lycopene cyclase protein Shikimate_DH PF01488.20 KFY00527.1 - 0.025 14.6 0.0 0.38 10.8 0.0 2.6 3 0 0 3 3 3 0 Shikimate / quinate 5-dehydrogenase GIDA PF01134.22 KFY00527.1 - 0.033 13.3 1.7 2.6 7.0 0.1 2.2 2 0 0 2 2 2 0 Glucose inhibited division protein A FAD_oxidored PF12831.7 KFY00527.1 - 0.061 12.7 0.0 0.85 8.9 0.0 2.1 2 0 0 2 2 2 0 FAD dependent oxidoreductase NAD_binding_7 PF13241.6 KFY00527.1 - 0.19 12.2 0.1 1.6 9.2 0.0 2.5 3 1 0 3 3 3 0 Putative NAD(P)-binding Hydrolase_4 PF12146.8 KFY00528.1 - 4e-09 36.1 0.1 2e-08 33.8 0.0 2.1 1 1 0 1 1 1 1 Serine aminopeptidase, S33 DUF3887 PF13026.6 KFY00528.1 - 3e-06 28.0 0.0 6e-06 27.0 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3887) DLH PF01738.18 KFY00528.1 - 2.3e-05 24.0 0.0 0.04 13.5 0.0 2.2 2 0 0 2 2 2 2 Dienelactone hydrolase family BAAT_C PF08840.11 KFY00528.1 - 0.00032 20.7 0.0 0.00063 19.7 0.0 1.5 1 0 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_6 PF12697.7 KFY00528.1 - 0.00036 21.2 0.2 0.00073 20.2 0.1 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.7 KFY00528.1 - 0.007 16.1 0.0 0.014 15.1 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family CRISPR_Cse2 PF09485.10 KFY00528.1 - 0.034 14.7 0.0 5.1 7.6 0.0 2.3 2 0 0 2 2 2 0 CRISPR-associated protein Cse2 (CRISPR_cse2) PGAP1 PF07819.13 KFY00528.1 - 0.035 13.8 0.0 0.06 13.1 0.0 1.4 1 0 0 1 1 1 0 PGAP1-like protein Thioesterase PF00975.20 KFY00528.1 - 0.061 13.4 0.0 0.11 12.6 0.0 1.3 1 0 0 1 1 1 0 Thioesterase domain Abhydrolase_1 PF00561.20 KFY00528.1 - 0.073 12.7 0.0 0.16 11.6 0.0 1.5 2 0 0 2 2 2 0 alpha/beta hydrolase fold DBD_HTH PF18430.1 KFY00528.1 - 0.13 12.1 0.0 0.66 9.8 0.0 2.1 2 0 0 2 2 2 0 Putative DNA-binding domain Aldo_ket_red PF00248.21 KFY00529.1 - 3.1e-51 174.3 0.0 5.5e-42 144.0 0.0 2.0 1 1 1 2 2 2 2 Aldo/keto reductase family APH PF01636.23 KFY00530.1 - 7e-13 49.1 0.0 1.1e-12 48.4 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KFY00530.1 - 0.00097 18.8 0.0 0.0017 18.0 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase BATS PF06968.13 KFY00530.1 - 0.094 12.9 0.0 0.2 11.8 0.0 1.6 1 0 0 1 1 1 0 Biotin and Thiamin Synthesis associated domain Pkinase PF00069.25 KFY00531.1 - 0.019 14.3 0.0 0.033 13.6 0.0 1.3 1 0 0 1 1 1 0 Protein kinase domain Pkinase_Tyr PF07714.17 KFY00531.1 - 0.084 12.1 0.0 0.29 10.4 0.0 1.7 2 0 0 2 2 2 0 Protein tyrosine kinase IBR PF01485.21 KFY00532.1 - 4.9e-06 26.7 6.9 4.9e-06 26.7 6.9 5.0 4 2 0 4 4 4 2 IBR domain, a half RING-finger domain zf-C3HC4 PF00097.25 KFY00532.1 - 0.0026 17.6 1.8 0.0026 17.6 1.8 5.2 5 1 1 6 6 6 1 Zinc finger, C3HC4 type (RING finger) PadR PF03551.14 KFY00532.1 - 0.2 11.6 0.0 0.51 10.3 0.0 1.6 1 0 0 1 1 1 0 Transcriptional regulator PadR-like family DAP3 PF10236.9 KFY00535.1 - 5.8e-30 104.5 0.1 8.2e-30 104.0 0.1 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal death-associated protein 3 AAA_16 PF13191.6 KFY00535.1 - 6.1e-06 26.7 0.0 1.1e-05 25.9 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain T2SSE PF00437.20 KFY00535.1 - 0.00074 18.6 0.1 0.00082 18.5 0.1 1.2 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_14 PF13173.6 KFY00535.1 - 0.012 15.7 0.0 0.018 15.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 KFY00535.1 - 0.04 13.5 0.4 0.064 12.8 0.4 1.3 1 0 0 1 1 1 0 AAA domain RRS1 PF04939.12 KFY00536.1 - 4.7e-58 195.6 2.0 5.5e-58 195.4 2.0 1.0 1 0 0 1 1 1 1 Ribosome biogenesis regulatory protein (RRS1) MCM PF00493.23 KFY00537.1 - 1.4e-103 344.9 0.0 2.4e-103 344.1 0.0 1.4 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 KFY00537.1 - 2e-30 105.2 0.2 4.4e-30 104.1 0.2 1.5 1 0 0 1 1 1 1 MCM OB domain MCM_N PF14551.6 KFY00537.1 - 3.7e-20 72.5 2.7 9.3e-20 71.2 2.7 1.7 1 0 0 1 1 1 1 MCM N-terminal domain MCM_lid PF17855.1 KFY00537.1 - 2.4e-19 69.5 1.1 6.4e-19 68.2 1.1 1.8 1 0 0 1 1 1 1 MCM AAA-lid domain Mg_chelatase PF01078.21 KFY00537.1 - 9.2e-08 31.7 0.0 9e-06 25.2 0.0 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 KFY00537.1 - 3.5e-06 27.1 0.0 1e-05 25.6 0.0 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) RecX PF02631.16 KFY00537.1 - 0.058 13.9 1.5 0.47 10.9 0.2 2.4 2 0 0 2 2 2 0 RecX family Mg_chelatase_C PF13335.6 KFY00537.1 - 0.095 13.3 2.7 0.2 12.3 1.0 2.5 4 0 0 4 4 4 0 Magnesium chelatase, subunit ChlI C-terminal AAA_3 PF07726.11 KFY00537.1 - 0.11 12.4 0.0 0.39 10.6 0.0 2.0 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Ribosomal_L50 PF10501.9 KFY00550.1 - 4e-15 55.9 0.0 6.8e-15 55.2 0.0 1.5 1 0 0 1 1 1 1 Ribosomal subunit 39S Gtr1_RagA PF04670.12 KFY00551.1 - 6.2e-71 238.4 0.1 8.5e-71 238.0 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Thiolase_N PF00108.23 KFY00551.1 - 1.5e-70 237.6 1.7 2.1e-70 237.1 1.7 1.2 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 KFY00551.1 - 4.8e-41 139.3 0.6 1.2e-40 138.0 0.6 1.7 1 0 0 1 1 1 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 KFY00551.1 - 4.1e-06 26.6 0.9 1e-05 25.3 0.9 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Roc PF08477.13 KFY00551.1 - 0.012 15.8 0.0 0.022 14.9 0.0 1.5 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFY00551.1 - 0.013 14.9 0.0 0.027 13.9 0.0 1.5 1 0 0 1 1 1 0 ADP-ribosylation factor family ACP_syn_III PF08545.10 KFY00551.1 - 0.099 12.5 0.9 0.84 9.5 0.2 2.4 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III AAA_16 PF13191.6 KFY00551.1 - 0.16 12.3 0.0 0.45 10.9 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain SAP130_C PF16014.5 KFY00575.1 - 0.49 9.4 3.8 0.6 9.1 3.8 1.1 1 0 0 1 1 1 0 Histone deacetylase complex subunit SAP130 C-terminus KH_1 PF00013.29 KFY00577.1 - 5.1e-09 35.8 0.0 3.1e-06 26.9 0.0 2.6 2 0 0 2 2 2 2 KH domain SAP130_C PF16014.5 KFY00577.1 - 0.42 9.7 7.7 0.78 8.8 7.7 1.4 1 0 0 1 1 1 0 Histone deacetylase complex subunit SAP130 C-terminus Joubert PF15392.6 KFY00577.1 - 0.59 9.8 3.4 0.9 9.2 3.4 1.3 1 0 0 1 1 1 0 Joubert syndrome-associated UPF0181 PF03701.14 KFY00577.1 - 4.2 7.1 5.7 0.75 9.5 0.2 2.2 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0181) DUF2457 PF10446.9 KFY00577.1 - 8.4 5.4 13.7 13 4.8 13.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) ACT PF01842.25 KFY00578.1 - 3.8e-14 52.1 0.1 7.2e-14 51.3 0.1 1.5 1 0 0 1 1 1 1 ACT domain ALS_ss_C PF10369.9 KFY00578.1 - 4.3e-14 52.5 0.0 3.9e-13 49.4 0.0 2.3 2 0 0 2 2 2 1 Small subunit of acetolactate synthase ACT_5 PF13710.6 KFY00578.1 - 3.9e-08 33.0 0.0 6.6e-08 32.3 0.0 1.4 1 0 0 1 1 1 1 ACT domain ACT_6 PF13740.6 KFY00578.1 - 0.12 12.4 0.0 21 5.2 0.0 2.6 2 0 0 2 2 2 0 ACT domain MEIOC PF15189.6 KFY00578.1 - 0.14 11.8 0.0 0.24 11.0 0.0 1.3 1 0 0 1 1 1 0 Meiosis-specific coiled-coil domain-containing protein MEIOC DUF3712 PF12505.8 KFY00579.1 - 1.9e-08 34.6 4.9 6.5e-07 29.6 0.1 2.9 3 0 0 3 3 3 2 Protein of unknown function (DUF3712) DUF3246 PF11596.8 KFY00579.1 - 0.083 12.3 0.1 0.083 12.3 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3246) OTCace_N PF02729.21 KFY00580.1 - 8.9e-46 155.6 0.2 1.6e-45 154.7 0.2 1.5 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain OTCace PF00185.24 KFY00580.1 - 8e-42 143.0 0.0 1.2e-41 142.4 0.0 1.3 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain Mpp10 PF04006.12 KFY00581.1 - 2e-110 370.1 74.9 7.9e-110 368.1 74.9 1.7 1 1 0 1 1 1 1 Mpp10 protein Peptidase_S64 PF08192.11 KFY00581.1 - 0.85 8.0 2.8 2.1 6.8 2.8 1.6 1 0 0 1 1 1 0 Peptidase family S64 Oxidored_q6 PF01058.22 KFY00582.1 - 4.4e-22 78.3 0.0 6.4e-22 77.8 0.0 1.2 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase, 20 Kd subunit Zn_clus PF00172.18 KFY00583.1 - 4.3e-06 26.7 6.2 9e-06 25.7 6.2 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KFY00583.1 - 0.0023 17.0 0.0 0.0049 15.9 0.0 1.5 1 1 0 1 1 1 1 Fungal specific transcription factor domain zf-HYPF PF07503.12 KFY00583.1 - 1.3 8.8 6.0 3.2 7.6 0.7 2.8 2 0 0 2 2 2 0 HypF finger Ribosomal_L28 PF00830.19 KFY00584.1 - 4.5e-20 71.6 0.3 8.7e-20 70.7 0.3 1.4 1 0 0 1 1 1 1 Ribosomal L28 family SART-1 PF03343.13 KFY00585.1 - 3.4e-194 647.0 72.6 3.9e-194 646.8 72.6 1.0 1 0 0 1 1 1 1 SART-1 family Glyco_hydro_15 PF00723.21 KFY00586.1 - 1.9e-100 336.8 0.0 2.2e-100 336.6 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 15 CBM_20 PF00686.19 KFY00586.1 - 2.9e-32 110.4 0.7 8.1e-32 109.0 0.7 1.8 1 0 0 1 1 1 1 Starch binding domain PITH PF06201.13 KFY00587.1 - 9.1e-45 152.6 0.0 1.1e-44 152.3 0.0 1.1 1 0 0 1 1 1 1 PITH domain PP2C PF00481.21 KFY00588.1 - 2.5e-83 279.7 0.0 3.9e-83 279.0 0.0 1.3 1 0 0 1 1 1 1 Protein phosphatase 2C CTP_transf_like PF01467.26 KFY00589.1 - 1e-29 103.6 0.0 1.3e-29 103.2 0.0 1.1 1 0 0 1 1 1 1 Cytidylyltransferase-like DUF5639 PF18690.1 KFY00589.1 - 0.12 12.5 0.0 0.23 11.7 0.0 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5639) HIGH_NTase1 PF05636.11 KFY00589.1 - 0.25 10.5 0.0 0.32 10.2 0.0 1.1 1 0 0 1 1 1 0 HIGH Nucleotidyl Transferase ER_lumen_recept PF00810.18 KFY00591.1 - 1.7e-36 126.2 10.1 1.7e-36 126.2 10.1 1.6 2 0 0 2 2 2 1 ER lumen protein retaining receptor 7TMR-DISM_7TM PF07695.11 KFY00591.1 - 0.22 11.4 12.6 0.1 12.5 10.3 1.6 1 1 0 1 1 1 0 7TM diverse intracellular signalling PQ-loop PF04193.14 KFY00591.1 - 0.41 10.4 7.4 0.47 10.3 0.0 2.9 3 0 0 3 3 3 0 PQ loop repeat DUF1751 PF08551.10 KFY00591.1 - 0.79 10.3 5.3 0.81 10.3 0.8 2.6 1 1 1 2 2 2 0 Eukaryotic integral membrane protein (DUF1751) DSPc PF00782.20 KFY00597.1 - 7.8e-20 71.1 0.0 9.4e-20 70.8 0.0 1.1 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 KFY00597.1 - 0.0029 17.2 0.0 0.0034 17.0 0.0 1.1 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Init_tRNA_PT PF04179.12 KFY00597.1 - 0.005 17.1 0.1 0.12 12.6 0.1 2.2 1 1 0 1 1 1 1 Rit1 DUSP-like domain Peptidase_S64 PF08192.11 KFY00598.1 - 0.0066 15.0 0.2 0.0075 14.8 0.2 1.0 1 0 0 1 1 1 1 Peptidase family S64 Peptidase_S32 PF05579.13 KFY00598.1 - 0.03 13.5 0.1 0.032 13.4 0.1 1.0 1 0 0 1 1 1 0 Equine arteritis virus serine endopeptidase S32 PTPA PF03095.15 KFY00599.1 - 4.1e-102 341.7 0.0 5e-102 341.4 0.0 1.1 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein Spc7 PF08317.11 KFY00601.1 - 4.7e-07 29.0 164.7 7.9e-05 21.7 18.0 8.6 1 1 9 10 10 10 6 Spc7 kinetochore protein PKcGMP_CC PF16808.5 KFY00601.1 - 0.11 12.3 0.1 0.11 12.3 0.1 6.3 6 1 1 7 7 7 0 Coiled-coil N-terminus of cGMP-dependent protein kinase Filament PF00038.21 KFY00601.1 - 1.2 8.6 131.0 1.4 8.4 33.1 5.7 1 1 4 5 5 5 0 Intermediate filament protein SpmSyn_N PF17950.1 KFY00601.1 - 2.3 8.5 4.2 1 9.6 0.4 2.5 2 0 0 2 2 2 0 S-adenosylmethionine decarboxylase N -terminal Osmo_CC PF08946.10 KFY00601.1 - 6.8 7.0 22.1 9.7 6.5 2.1 6.5 5 1 1 6 6 6 0 Osmosensory transporter coiled coil Tht1 PF04163.12 KFY00602.1 - 0.0016 17.3 3.1 0.0028 16.5 3.1 1.3 1 0 0 1 1 1 1 Tht1-like nuclear fusion protein ApoLp-III PF07464.11 KFY00602.1 - 0.0073 16.4 2.6 0.0073 16.4 2.6 2.0 2 0 0 2 2 2 1 Apolipophorin-III precursor (apoLp-III) AAA_16 PF13191.6 KFY00602.1 - 0.02 15.3 1.8 0.064 13.6 1.8 1.9 1 1 0 1 1 1 0 AAA ATPase domain DAPDH_C PF16654.5 KFY00602.1 - 0.092 12.6 0.0 0.19 11.6 0.0 1.5 1 0 0 1 1 1 0 Diaminopimelic acid dehydrogenase C-terminal domain NPV_P10 PF05531.12 KFY00602.1 - 0.13 12.8 4.4 6.8 7.2 0.5 2.8 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein ZYG-11_interact PF05884.12 KFY00602.1 - 0.14 11.6 4.6 0.87 8.9 1.0 2.8 1 1 1 2 2 2 0 Interactor of ZYG-11 CENP-F_leu_zip PF10473.9 KFY00602.1 - 0.15 12.1 4.9 4.5 7.3 0.0 2.4 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Syntaxin PF00804.25 KFY00602.1 - 0.39 10.4 8.1 0.16 11.6 0.3 2.8 1 1 2 3 3 3 0 Syntaxin TMPIT PF07851.13 KFY00602.1 - 0.46 9.7 3.2 0.46 9.7 0.2 2.0 1 1 1 2 2 2 0 TMPIT-like protein DUF3450 PF11932.8 KFY00602.1 - 1.1 8.6 14.9 1.1 8.5 8.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) WXG100 PF06013.12 KFY00602.1 - 2.7 8.3 14.3 3.4 7.9 0.4 3.4 1 1 0 2 2 2 0 Proteins of 100 residues with WXG Spc7 PF08317.11 KFY00602.1 - 4.1 6.2 11.3 2.5 6.9 4.8 2.1 1 1 1 2 2 2 0 Spc7 kinetochore protein Ribosomal_L6 PF00347.23 KFY00603.1 - 1.4e-22 80.2 0.0 1.6e-11 44.7 0.0 2.6 2 1 0 2 2 2 2 Ribosomal protein L6 Inositol_P PF00459.25 KFY00604.1 - 4.8e-53 180.4 1.2 1.3e-52 179.0 1.2 1.5 1 1 0 1 1 1 1 Inositol monophosphatase family zf-C3HC PF07967.13 KFY00605.1 - 1.1e-33 116.1 0.0 9.5e-32 109.8 0.0 2.5 2 0 0 2 2 2 1 C3HC zinc finger-like Rsm1 PF08600.10 KFY00605.1 - 2.1e-18 66.3 2.0 1.8e-16 60.1 0.0 2.9 2 1 0 2 2 2 1 Rsm1-like BIR PF00653.21 KFY00605.1 - 0.039 14.6 0.1 0.93 10.2 0.1 2.4 2 0 0 2 2 2 0 Inhibitor of Apoptosis domain TT_ORF2 PF02957.15 KFY00605.1 - 0.38 11.7 4.2 4.9 8.1 2.3 2.6 2 0 0 2 2 2 0 TT viral ORF2 Dsh_C PF12316.8 KFY00605.1 - 6.2 7.2 9.5 0.37 11.2 3.5 1.9 2 0 0 2 2 2 0 Segment polarity protein dishevelled (Dsh) C terminal NicO PF03824.16 KFY00606.1 - 0.004 16.5 1.5 0.0048 16.3 1.5 1.1 1 0 0 1 1 1 1 High-affinity nickel-transport protein SelP_N PF04592.14 KFY00606.1 - 2.1 7.7 12.0 2.5 7.4 12.0 1.1 1 0 0 1 1 1 0 Selenoprotein P, N terminal region AA_permease PF00324.21 KFY00608.1 - 3.1e-103 346.0 36.5 3.7e-103 345.7 36.5 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KFY00608.1 - 6.4e-21 74.7 36.9 1e-20 74.0 36.9 1.4 1 0 0 1 1 1 1 Amino acid permease DUF2207 PF09972.9 KFY00608.1 - 3.8 6.1 16.7 0.79 8.4 0.9 3.1 3 1 0 3 3 3 0 Predicted membrane protein (DUF2207) PEX11 PF05648.14 KFY00609.1 - 2.7e-28 99.0 0.0 3.1e-28 98.8 0.0 1.0 1 0 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) Peptidase_M20 PF01546.28 KFY00610.1 - 3e-29 102.2 0.0 4.3e-29 101.7 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 KFY00610.1 - 5.2e-11 42.4 0.0 9.9e-11 41.5 0.0 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 KFY00610.1 - 0.0051 16.5 0.0 0.014 15.1 0.0 1.7 1 1 0 1 1 1 1 Peptidase family M28 Peptidase_M24 PF00557.24 KFY00611.1 - 3.7e-21 75.8 0.1 5e-21 75.3 0.1 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 Creatinase_N PF01321.18 KFY00611.1 - 1e-17 65.0 0.0 1.7e-17 64.3 0.0 1.4 1 0 0 1 1 1 1 Creatinase/Prolidase N-terminal domain Beta_elim_lyase PF01212.21 KFY00612.1 - 2.3e-79 266.8 0.0 3.2e-79 266.3 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_1_2 PF00155.21 KFY00612.1 - 0.00033 19.9 0.1 0.0011 18.2 0.1 1.8 1 1 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 KFY00612.1 - 0.013 14.1 0.0 0.019 13.5 0.0 1.3 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.17 KFY00612.1 - 0.068 12.5 0.1 0.39 10.0 0.0 2.0 2 1 0 2 2 2 0 DegT/DnrJ/EryC1/StrS aminotransferase family PIN_12 PF16289.5 KFY00612.1 - 0.11 13.0 0.0 0.21 12.1 0.0 1.5 1 0 0 1 1 1 0 PIN domain Aldedh PF00171.22 KFY00613.1 - 4.2e-183 609.1 0.3 4.7e-183 608.9 0.3 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Glyco_hydro_32C PF08244.12 KFY00614.1 - 3.1e-22 79.3 0.5 4.5e-22 78.7 0.5 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 C terminal Glyco_hydro_32N PF00251.20 KFY00614.1 - 3.6e-14 53.0 0.0 6e-14 52.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 N-terminal domain Pkinase PF00069.25 KFY00615.1 - 1.4e-41 142.6 0.0 2.4e-39 135.3 0.0 2.6 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KFY00615.1 - 8.4e-25 87.5 0.0 2.7e-24 85.9 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase DUF5608 PF18356.1 KFY00615.1 - 0.13 12.3 0.1 0.3 11.1 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5608) S4 PF01479.25 KFY00616.1 - 5.2e-12 45.3 0.0 1e-11 44.4 0.0 1.5 1 0 0 1 1 1 1 S4 domain Ribosomal_S4 PF00163.19 KFY00616.1 - 5.8e-11 43.2 0.1 8.3e-11 42.7 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain Glycoamylase PF10091.9 KFY00616.1 - 0.12 12.0 0.2 0.2 11.2 0.2 1.4 1 1 0 1 1 1 0 Putative glucoamylase Clr5 PF14420.6 KFY00617.1 - 9.2e-07 29.0 1.3 1.8e-06 28.1 1.3 1.5 1 0 0 1 1 1 1 Clr5 domain Glyco_hydro_3_C PF01915.22 KFY00618.1 - 5.8e-41 140.7 0.0 1e-40 139.9 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 KFY00618.1 - 2.9e-34 118.9 0.0 4.4e-34 118.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 KFY00618.1 - 4e-07 30.0 0.0 8.6e-07 29.0 0.0 1.6 1 0 0 1 1 1 1 Fibronectin type III-like domain TraE PF05309.11 KFY00619.1 - 0.017 14.5 0.0 0.037 13.4 0.0 1.5 1 0 0 1 1 1 0 TraE protein CDP-OH_P_transf PF01066.21 KFY00619.1 - 0.23 12.2 1.9 0.91 10.3 0.0 2.9 2 1 0 2 2 2 0 CDP-alcohol phosphatidyltransferase FAD_binding_4 PF01565.23 KFY00620.1 - 5e-23 81.4 4.6 9.4e-23 80.5 4.6 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 KFY00620.1 - 0.00024 21.1 0.0 0.00051 20.1 0.0 1.6 1 0 0 1 1 1 1 Berberine and berberine like MFS_1 PF07690.16 KFY00621.1 - 1e-27 97.0 19.5 1e-27 97.0 19.5 1.6 1 1 1 2 2 2 2 Major Facilitator Superfamily TauD PF02668.16 KFY00622.1 - 2.5e-54 184.9 0.3 4.1e-52 177.6 0.3 2.1 1 1 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Fungal_trans_2 PF11951.8 KFY00623.1 - 2e-51 175.0 0.0 3.5e-51 174.2 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.26 KFY00623.1 - 5.6e-07 29.7 12.0 0.0058 17.0 4.3 3.0 2 0 0 2 2 2 2 Zinc finger, C2H2 type Zn_clus PF00172.18 KFY00623.1 - 5.2e-06 26.5 21.7 5.7e-05 23.1 8.8 3.3 4 0 0 4 4 4 2 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-H2C2_2 PF13465.6 KFY00623.1 - 0.00037 20.8 3.0 0.00037 20.8 3.0 4.3 4 1 0 4 4 4 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 KFY00623.1 - 0.0011 19.6 17.2 0.033 15.0 1.0 3.5 3 0 0 3 3 3 2 C2H2-type zinc finger BolA PF01722.18 KFY00623.1 - 0.0072 16.6 0.9 0.3 11.4 0.3 2.4 1 1 1 2 2 2 2 BolA-like protein zf-C2H2_6 PF13912.6 KFY00623.1 - 0.022 14.8 1.0 0.022 14.8 1.0 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFY00623.1 - 0.027 14.8 3.1 6.6 7.2 0.1 2.8 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KFY00623.1 - 0.077 13.4 3.9 5.4 7.5 0.4 2.9 2 0 0 2 2 2 0 Zinc-finger of C2H2 type Glyco_hydro_3_C PF01915.22 KFY00624.1 - 2.9e-42 145.0 0.0 4.4e-42 144.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 KFY00624.1 - 1.7e-38 132.8 0.0 2.5e-38 132.2 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain WSC PF01822.19 KFY00624.1 - 3.9e-15 55.8 9.2 8.9e-15 54.7 9.2 1.7 1 0 0 1 1 1 1 WSC domain Toxin_3 PF00537.18 KFY00624.1 - 1.6 9.0 5.4 0.21 11.8 0.6 2.0 2 0 0 2 2 2 0 Scorpion toxin-like domain Amidohydro_1 PF01979.20 KFY00625.1 - 9.2e-73 245.5 0.1 1.1e-72 245.3 0.1 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 KFY00625.1 - 4.6e-20 72.5 0.4 6.9e-16 58.8 0.1 2.1 2 0 0 2 2 2 2 Amidohydrolase family A_deaminase PF00962.22 KFY00625.1 - 0.00065 19.1 0.0 0.0018 17.7 0.0 1.7 1 1 0 1 1 1 1 Adenosine/AMP deaminase Xan_ur_permease PF00860.20 KFY00626.1 - 1.3e-69 234.8 33.6 2.4e-68 230.6 33.6 2.1 1 1 0 1 1 1 1 Permease family ABC2_membrane PF01061.24 KFY00627.1 - 2.1e-29 102.5 29.9 3.2e-29 101.9 29.9 1.2 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.27 KFY00627.1 - 7.2e-26 91.3 0.0 1.1e-25 90.8 0.0 1.3 1 0 0 1 1 1 1 ABC transporter RsgA_GTPase PF03193.16 KFY00627.1 - 2.4e-06 27.6 0.4 1.9e-05 24.6 0.1 2.1 2 0 0 2 2 2 1 RsgA GTPase AAA_25 PF13481.6 KFY00627.1 - 1.5e-05 24.7 0.1 2.8e-05 23.8 0.1 1.4 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KFY00627.1 - 8.6e-05 23.0 0.1 0.00014 22.3 0.1 1.4 1 0 0 1 1 1 1 AAA ATPase domain AAA_21 PF13304.6 KFY00627.1 - 0.00088 19.2 0.0 0.49 10.1 0.0 2.2 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system Rad17 PF03215.15 KFY00627.1 - 0.0025 17.8 0.0 0.0042 17.0 0.0 1.3 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_22 PF13401.6 KFY00627.1 - 0.0074 16.6 0.1 0.018 15.3 0.1 1.8 1 1 0 1 1 1 1 AAA domain AAA PF00004.29 KFY00627.1 - 0.011 16.2 0.1 0.043 14.2 0.1 1.9 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) IstB_IS21 PF01695.17 KFY00627.1 - 0.012 15.3 0.1 0.029 14.1 0.0 1.6 2 0 0 2 2 1 0 IstB-like ATP binding protein AAA_30 PF13604.6 KFY00627.1 - 0.015 15.0 0.2 0.023 14.4 0.2 1.3 1 0 0 1 1 1 0 AAA domain SMC_N PF02463.19 KFY00627.1 - 0.016 14.7 0.0 0.07 12.6 0.0 1.9 1 1 0 1 1 1 0 RecF/RecN/SMC N terminal domain AAA_28 PF13521.6 KFY00627.1 - 0.019 15.2 0.2 0.033 14.4 0.2 1.4 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 KFY00627.1 - 0.025 14.6 0.0 0.049 13.7 0.0 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase T2SSE PF00437.20 KFY00627.1 - 0.038 13.0 0.0 0.06 12.4 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein NACHT PF05729.12 KFY00627.1 - 0.063 13.2 0.0 0.11 12.5 0.0 1.4 1 0 0 1 1 1 0 NACHT domain AAA_29 PF13555.6 KFY00627.1 - 0.091 12.5 0.0 0.23 11.2 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_24 PF13479.6 KFY00627.1 - 0.1 12.3 0.0 0.18 11.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 KFY00627.1 - 0.11 12.9 0.0 0.22 11.9 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_5 PF07728.14 KFY00627.1 - 0.14 12.1 0.0 0.31 11.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) ATPase_2 PF01637.18 KFY00627.1 - 0.2 11.5 0.0 0.34 10.8 0.0 1.3 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_18 PF13238.6 KFY00627.1 - 0.23 12.0 0.1 0.51 10.9 0.1 1.6 1 0 0 1 1 1 0 AAA domain AAA_13 PF13166.6 KFY00627.1 - 0.41 9.2 0.3 0.9 8.1 0.0 1.5 2 0 0 2 2 2 0 AAA domain Fungal_trans PF04082.18 KFY00628.1 - 0.0002 20.5 0.0 0.00031 19.9 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain adh_short PF00106.25 KFY00629.1 - 8.5e-27 93.9 0.0 1.1e-26 93.5 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KFY00629.1 - 2.8e-12 46.7 0.0 4.6e-12 46.0 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF1776 PF08643.10 KFY00629.1 - 2.9e-06 26.9 0.1 3.3e-06 26.7 0.1 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) KR PF08659.10 KFY00629.1 - 0.07 13.0 0.1 0.17 11.8 0.1 1.7 1 1 0 1 1 1 0 KR domain GST_N_2 PF13409.6 KFY00630.1 - 2.1e-07 31.1 0.0 3.9e-07 30.3 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 KFY00630.1 - 1.6e-06 28.4 0.0 3.9e-06 27.2 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 KFY00630.1 - 0.003 17.7 0.0 0.0057 16.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 KFY00630.1 - 0.16 12.0 0.0 0.3 11.1 0.0 1.7 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain p450 PF00067.22 KFY00631.1 - 1.6e-78 264.6 0.0 1.8e-78 264.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 MFS_1 PF07690.16 KFY00632.1 - 3.5e-16 59.1 64.4 5.5e-14 51.8 37.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 KFY00632.1 - 0.00085 18.7 13.3 0.0014 18.1 13.3 1.2 1 0 0 1 1 1 1 Uncharacterised MFS-type transporter YbfB PRKCSH-like PF12999.7 KFY00633.1 - 1.5e-45 155.2 1.5 6.9e-25 87.8 0.2 2.9 2 0 0 2 2 2 2 Glucosidase II beta subunit-like PRKCSH_1 PF13015.6 KFY00633.1 - 3.3e-30 104.8 3.4 4.6e-30 104.3 0.9 2.1 2 0 0 2 2 2 1 Glucosidase II beta subunit-like protein PRKCSH PF07915.13 KFY00633.1 - 5.2e-10 40.2 0.3 1.8e-09 38.5 0.3 2.0 1 0 0 1 1 1 1 Glucosidase II beta subunit-like protein ATG27 PF09451.10 KFY00633.1 - 0.00051 20.0 0.6 0.0012 18.7 0.6 1.6 1 0 0 1 1 1 1 Autophagy-related protein 27 Mod_r PF07200.13 KFY00633.1 - 1.6 8.8 8.1 1.4 9.0 0.1 2.6 2 1 1 3 3 3 0 Modifier of rudimentary (Mod(r)) protein Ax_dynein_light PF10211.9 KFY00633.1 - 1.9 8.4 8.5 0.17 11.8 3.6 1.8 2 0 0 2 2 2 0 Axonemal dynein light chain Ldl_recept_a PF00057.18 KFY00633.1 - 2.4 8.4 9.8 1.9 8.8 1.4 2.8 2 0 0 2 2 2 0 Low-density lipoprotein receptor domain class A Fe-S_biosyn PF01521.20 KFY00634.1 - 4e-15 56.0 0.0 1.5e-13 50.9 0.0 2.1 1 1 0 1 1 1 1 Iron-sulphur cluster biosynthesis Ribosomal_L30_N PF08079.12 KFY00635.1 - 1.3e-26 92.7 18.5 1.3e-26 92.7 18.5 1.6 2 0 0 2 2 2 1 Ribosomal L30 N-terminal domain Ribosomal_L30 PF00327.20 KFY00635.1 - 3.2e-18 65.3 2.5 7.6e-18 64.2 2.5 1.7 1 0 0 1 1 1 1 Ribosomal protein L30p/L7e Trypan_PARP PF05887.11 KFY00636.1 - 0.95 9.4 21.0 1.5 8.8 21.0 1.4 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Pkinase PF00069.25 KFY00637.1 - 2.1e-68 230.5 0.0 2.8e-68 230.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFY00637.1 - 1.1e-30 106.8 0.0 1.6e-30 106.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.24 KFY00637.1 - 4.1e-13 49.8 0.1 2.5e-12 47.3 0.1 2.5 1 0 0 1 1 1 1 Protein kinase C terminal domain C2 PF00168.30 KFY00637.1 - 5.9e-09 36.2 0.0 3.2e-06 27.4 0.0 2.8 2 0 0 2 2 2 1 C2 domain Kinase-like PF14531.6 KFY00637.1 - 1.7e-08 34.1 0.0 5.4e-08 32.5 0.0 1.7 1 1 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 KFY00637.1 - 0.0022 17.0 0.1 0.0022 17.0 0.1 2.1 2 1 0 2 2 2 1 Haspin like kinase domain FTA2 PF13095.6 KFY00637.1 - 0.05 13.2 1.2 1.7 8.2 0.1 2.8 3 0 0 3 3 3 0 Kinetochore Sim4 complex subunit FTA2 Adeno_E3_15_3 PF03307.14 KFY00637.1 - 0.059 13.3 0.1 0.11 12.4 0.1 1.3 1 0 0 1 1 1 0 Adenovirus 15.3kD protein in E3 region APH PF01636.23 KFY00637.1 - 0.08 12.8 0.0 0.13 12.1 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Choline_kinase PF01633.20 KFY00637.1 - 0.1 12.2 0.1 0.17 11.5 0.1 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase Kdo PF06293.14 KFY00637.1 - 0.14 11.4 0.1 0.24 10.7 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family EPL1 PF10513.9 KFY00637.1 - 0.19 12.1 0.0 0.19 12.1 0.0 2.3 2 1 0 2 2 1 0 Enhancer of polycomb-like ATP_sub_h PF10775.9 KFY00638.1 - 9.2e-27 92.8 1.4 1.3e-26 92.4 1.4 1.2 1 0 0 1 1 1 1 ATP synthase complex subunit h TFIIB PF00382.19 KFY00639.1 - 3.7e-33 113.4 0.0 7.2e-18 64.4 0.0 2.3 2 0 0 2 2 2 2 Transcription factor TFIIB repeat TF_Zn_Ribbon PF08271.12 KFY00639.1 - 8.4e-14 50.8 1.5 1.4e-13 50.1 1.5 1.3 1 0 0 1 1 1 1 TFIIB zinc-binding Cyclin_C PF02984.19 KFY00639.1 - 0.0052 16.9 0.0 0.4 10.8 0.0 2.3 2 0 0 2 2 2 1 Cyclin, C-terminal domain Sigma70_r4 PF04545.16 KFY00639.1 - 0.037 13.6 0.0 0.13 11.8 0.0 1.9 2 0 0 2 2 2 0 Sigma-70, region 4 zf-ribbon_3 PF13248.6 KFY00639.1 - 0.044 13.2 0.5 0.26 10.7 0.0 2.3 2 0 0 2 2 2 0 zinc-ribbon domain Sugar_tr PF00083.24 KFY00640.1 - 2.1e-69 234.6 25.3 2.7e-69 234.2 25.3 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KFY00640.1 - 5.4e-19 68.3 28.6 5.4e-19 68.3 28.6 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 KFY00640.1 - 1.7e-09 36.8 21.0 4.5e-07 28.8 3.1 3.3 2 1 1 3 3 3 3 MFS/sugar transport protein DUF4792 PF16040.5 KFY00640.1 - 0.018 15.0 0.3 0.05 13.5 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4792) DUF5539 PF17693.1 KFY00640.1 - 0.098 12.3 0.5 0.18 11.4 0.5 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5539) Ras PF00071.22 KFY00643.1 - 2.2e-40 137.9 0.0 2.6e-38 131.2 0.0 2.1 2 0 0 2 2 2 1 Ras family Roc PF08477.13 KFY00643.1 - 3.5e-31 107.9 0.0 4.8e-31 107.5 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFY00643.1 - 1.7e-10 40.6 0.0 3e-10 39.8 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 KFY00643.1 - 0.00043 19.7 0.0 0.00061 19.2 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 KFY00643.1 - 0.003 17.6 0.0 0.0057 16.7 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.6 KFY00643.1 - 0.0072 16.7 0.0 0.01 16.2 0.0 1.5 1 1 0 1 1 1 1 AAA ATPase domain SRPRB PF09439.10 KFY00643.1 - 0.034 13.6 0.0 0.052 13.0 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_24 PF13479.6 KFY00643.1 - 0.055 13.2 0.0 0.092 12.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 KFY00643.1 - 0.064 13.4 0.0 0.11 12.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain Dynamin_N PF00350.23 KFY00643.1 - 0.069 13.2 0.0 0.1 12.6 0.0 1.3 1 0 0 1 1 1 0 Dynamin family AAA_5 PF07728.14 KFY00643.1 - 0.11 12.5 0.0 0.17 11.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Peptidase_S41 PF03572.18 KFY00645.1 - 6.6e-07 29.1 0.0 1.9e-06 27.5 0.0 1.7 1 1 0 1 1 1 1 Peptidase family S41 Abhydrolase_3 PF07859.13 KFY00646.1 - 4.1e-39 134.6 0.0 5.1e-39 134.3 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KFY00646.1 - 2.6e-05 24.9 2.7 4.9e-05 24.1 2.7 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family COesterase PF00135.28 KFY00646.1 - 0.00089 18.2 0.0 0.0057 15.6 0.0 2.0 2 0 0 2 2 2 1 Carboxylesterase family Hydrolase_4 PF12146.8 KFY00646.1 - 0.14 11.4 0.0 0.17 11.1 0.0 1.2 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Robl_LC7 PF03259.17 KFY00648.1 - 1.3e-06 28.1 0.0 6.2e-05 22.7 0.0 2.1 2 0 0 2 2 2 2 Roadblock/LC7 domain DUF3275 PF11679.8 KFY00648.1 - 0.13 12.2 0.0 0.15 12.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3275) Ipi1_N PF12333.8 KFY00649.1 - 5.7e-27 94.3 0.0 6e-26 91.0 0.0 2.8 2 1 1 3 3 3 1 Rix1 complex component involved in 60S ribosome maturation DUF262 PF03235.14 KFY00649.1 - 2.3e-16 60.7 0.1 1.2e-15 58.3 0.0 2.2 2 1 0 2 2 2 1 Protein of unknown function DUF262 DASH_Hsk3 PF08227.11 KFY00650.1 - 1e-11 45.0 0.0 1.9e-11 44.1 0.0 1.4 1 0 0 1 1 1 1 DASH complex subunit Hsk3 like p450 PF00067.22 KFY00651.1 - 4.5e-31 108.1 0.0 8.1e-31 107.3 0.0 1.3 1 1 0 1 1 1 1 Cytochrome P450 Ctr PF04145.15 KFY00652.1 - 9.9e-30 104.1 0.1 1.7e-29 103.4 0.1 1.4 1 0 0 1 1 1 1 Ctr copper transporter family Malate_synthase PF01274.22 KFY00653.1 - 5.3e-230 764.1 0.0 6e-230 764.0 0.0 1.0 1 0 0 1 1 1 1 Malate synthase Rpr2 PF04032.16 KFY00654.1 - 8.8e-26 90.0 0.2 2.1e-25 88.8 0.2 1.6 1 0 0 1 1 1 1 RNAse P Rpr2/Rpp21/SNM1 subunit domain DEAD PF00270.29 KFY00655.1 - 1.4e-37 129.1 0.2 2.4e-37 128.4 0.2 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KFY00655.1 - 3.6e-26 91.7 0.3 2.2e-23 82.7 0.1 2.6 3 0 0 3 3 3 2 Helicase conserved C-terminal domain ResIII PF04851.15 KFY00655.1 - 3e-10 40.3 0.1 6.4e-10 39.3 0.0 1.5 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Pkinase PF00069.25 KFY00676.1 - 2.4e-71 240.2 0.0 2.4e-71 240.2 0.0 1.4 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFY00676.1 - 1.9e-44 151.9 0.0 3.2e-44 151.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase PBD PF00786.28 KFY00676.1 - 7.3e-22 77.5 0.1 2.3e-21 75.9 0.1 1.9 1 0 0 1 1 1 1 P21-Rho-binding domain Pkinase_fungal PF17667.1 KFY00676.1 - 8.4e-08 31.4 2.3 5.9e-07 28.6 0.0 2.4 2 0 0 2 2 2 1 Fungal protein kinase Kinase-like PF14531.6 KFY00676.1 - 2e-07 30.6 0.0 3.7e-07 29.8 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 KFY00676.1 - 0.037 13.4 0.1 0.43 9.9 0.0 2.1 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KFY00676.1 - 0.093 12.6 0.0 0.22 11.4 0.0 1.7 1 0 0 1 1 1 0 Phosphotransferase enzyme family FTA2 PF13095.6 KFY00676.1 - 0.42 10.2 0.0 0.42 10.2 0.0 1.9 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 TFIIA PF03153.13 KFY00676.1 - 1.5 8.8 32.6 0.015 15.3 20.4 2.2 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit PAT1 PF09770.9 KFY00676.1 - 4.5 5.4 20.0 7.6 4.7 20.0 1.3 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Haspin_kinase PF12330.8 KFY00676.1 - 8.9 5.1 12.8 0.061 12.3 0.5 2.8 2 1 0 2 2 2 0 Haspin like kinase domain YlmH_RBD PF17774.1 KFY00679.1 - 0.038 14.3 0.0 0.056 13.7 0.0 1.2 1 0 0 1 1 1 0 Putative RNA-binding domain in YlmH DUF5300 PF17224.3 KFY00680.1 - 0.026 14.8 0.8 0.4 11.0 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF5300) SAYSvFN PF10260.9 KFY00680.1 - 0.069 13.1 2.0 1.3 9.0 0.1 3.1 2 1 0 2 2 2 0 Uncharacterized conserved domain (SAYSvFN) Antig_Caf1 PF09255.10 KFY00680.1 - 0.64 10.1 3.6 5.2 7.2 0.5 2.1 1 1 0 2 2 2 0 Caf1 Capsule antigen Chromo_shadow PF01393.19 KFY00682.1 - 3.1e-15 56.0 1.0 2.4e-13 49.9 0.4 2.4 2 0 0 2 2 2 2 Chromo shadow domain Chromo PF00385.24 KFY00682.1 - 4.6e-11 42.4 0.3 4.6e-11 42.4 0.3 2.1 2 1 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain MTHFR PF02219.17 KFY00682.1 - 0.12 11.7 0.2 7.4 5.8 0.0 2.1 2 0 0 2 2 2 0 Methylenetetrahydrofolate reductase Myc_N PF01056.18 KFY00682.1 - 0.17 11.8 9.2 0.095 12.6 5.9 1.9 2 0 0 2 2 2 0 Myc amino-terminal region DUF21 PF01595.20 KFY00684.1 - 1.3e-28 99.9 0.0 2.6e-28 98.9 0.0 1.4 1 0 0 1 1 1 1 Cyclin M transmembrane N-terminal domain CBS PF00571.28 KFY00684.1 - 1.1e-06 28.9 0.2 0.017 15.6 0.0 2.7 2 0 0 2 2 2 2 CBS domain Fibrinogen_aC PF12160.8 KFY00684.1 - 0.013 15.3 0.9 0.039 13.8 0.9 1.8 1 0 0 1 1 1 0 Fibrinogen alpha C domain Flavoprotein PF02441.19 KFY00685.1 - 4.2e-19 68.8 0.0 6.8e-19 68.2 0.0 1.3 1 0 0 1 1 1 1 Flavoprotein DHHC PF01529.20 KFY00686.1 - 1.4e-22 80.3 5.9 1.4e-22 80.3 5.9 2.8 3 1 0 3 3 3 1 DHHC palmitoyltransferase DUF1418 PF07214.12 KFY00686.1 - 0.56 10.1 6.1 0.25 11.2 2.6 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1418) YrhC PF14143.6 KFY00686.1 - 0.84 9.8 7.8 0.052 13.6 1.8 2.1 2 0 0 2 2 2 0 YrhC-like protein ARID PF01388.21 KFY00687.1 - 6.9e-17 61.9 0.0 3.2e-09 37.4 0.0 2.6 2 0 0 2 2 2 2 ARID/BRIGHT DNA binding domain Myb_DNA-bind_2 PF08914.11 KFY00687.1 - 1.3e-16 60.6 0.5 6.6e-16 58.2 0.1 2.5 2 0 0 2 2 2 1 Rap1 Myb domain Rap1_C PF11626.8 KFY00687.1 - 5.2e-15 55.3 0.3 1.3e-14 54.1 0.3 1.7 1 0 0 1 1 1 1 TRF2-interacting telomeric protein/Rap1 - C terminal domain BRCT_2 PF16589.5 KFY00687.1 - 0.00028 21.2 0.0 0.0017 18.7 0.0 2.3 1 1 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain Rap1-DNA-bind PF09197.10 KFY00687.1 - 0.0022 18.6 2.9 0.0026 18.3 0.0 2.7 3 0 0 3 3 3 1 Rap1, DNA-binding VHS PF00790.19 KFY00689.1 - 8.7e-24 84.0 0.0 2.2e-23 82.7 0.0 1.7 2 0 0 2 2 2 1 VHS domain GAT PF03127.14 KFY00689.1 - 3e-06 27.5 1.5 9.4e-06 25.9 1.5 1.9 1 0 0 1 1 1 1 GAT domain PTPS PF01242.19 KFY00690.1 - 0.084 12.8 0.3 0.44 10.5 0.1 2.2 2 0 0 2 2 2 0 6-pyruvoyl tetrahydropterin synthase KH_1 PF00013.29 KFY00694.1 - 1.9e-78 258.2 17.7 3.5e-13 49.2 0.2 10.5 10 2 0 10 10 10 8 KH domain SLS PF14611.6 KFY00694.1 - 1e-10 41.9 1.4 0.062 13.1 0.0 5.6 4 2 0 4 4 4 3 Mitochondrial inner-membrane-bound regulator KH_2 PF07650.17 KFY00694.1 - 1.5e-10 40.7 23.9 0.021 14.6 0.2 6.9 5 2 1 7 7 7 4 KH domain KH_4 PF13083.6 KFY00694.1 - 9.1e-05 22.3 9.6 0.57 10.1 0.2 5.6 6 0 0 6 6 6 2 KH domain DUF2120 PF09893.9 KFY00694.1 - 0.085 13.0 0.5 6 7.0 0.0 3.1 2 1 1 3 3 3 0 Uncharacterized protein conserved in archaea (DUF2120) DUF211 PF02680.14 KFY00694.1 - 0.15 12.2 2.2 44 4.3 0.0 4.4 4 0 0 4 4 4 0 Uncharacterized ArCR, COG1888 DnaJ-X PF14308.6 KFY00697.1 - 4.4e-76 255.0 3.1 4.4e-76 255.0 3.1 2.4 2 0 0 2 2 2 1 X-domain of DnaJ-containing DnaJ PF00226.31 KFY00697.1 - 9.1e-25 86.6 0.3 2e-24 85.5 0.3 1.6 1 0 0 1 1 1 1 DnaJ domain RmlD_sub_bind PF04321.17 KFY00697.1 - 2.2e-13 49.9 0.0 4.6e-13 48.9 0.0 1.5 1 1 0 1 1 1 1 RmlD substrate binding domain Epimerase PF01370.21 KFY00697.1 - 8.4e-13 48.3 0.0 1.7e-12 47.4 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 KFY00697.1 - 5.4e-05 22.5 0.1 0.00066 18.9 0.0 2.5 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein GDP_Man_Dehyd PF16363.5 KFY00697.1 - 0.0037 16.7 0.0 0.012 15.1 0.0 1.9 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Macro PF01661.21 KFY00697.1 - 0.082 13.0 0.0 0.28 11.2 0.0 1.9 1 0 0 1 1 1 0 Macro domain C2-set_2 PF08205.12 KFY00697.1 - 0.12 12.5 0.1 0.29 11.2 0.1 1.6 1 0 0 1 1 1 0 CD80-like C2-set immunoglobulin domain Cyt-b5 PF00173.28 KFY00699.1 - 3.7e-15 55.8 0.0 5.6e-15 55.2 0.0 1.3 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain NIBRIN_BRCT_II PF16508.5 KFY00700.1 - 9.5e-37 126.0 0.0 2.4e-36 124.6 0.0 1.8 1 0 0 1 1 1 1 Second BRCT domain on Nijmegen syndrome breakage protein FHA PF00498.26 KFY00700.1 - 3.3e-08 33.7 0.2 7.8e-08 32.6 0.2 1.7 1 0 0 1 1 1 1 FHA domain RTT107_BRCT_5 PF16770.5 KFY00700.1 - 5.2e-05 23.1 0.0 0.00014 21.6 0.0 1.7 1 0 0 1 1 1 1 Regulator of Ty1 transposition protein 107 BRCT domain Prot_ATP_ID_OB PF16450.5 KFY00700.1 - 0.032 14.2 0.1 0.097 12.6 0.1 1.9 1 0 0 1 1 1 0 Proteasomal ATPase OB C-terminal domain TRM PF02005.16 KFY00701.1 - 5e-108 361.6 0.0 3.2e-94 316.2 0.0 2.1 2 0 0 2 2 2 2 N2,N2-dimethylguanosine tRNA methyltransferase Met_10 PF02475.16 KFY00701.1 - 0.055 13.2 0.0 0.16 11.7 0.0 1.8 1 0 0 1 1 1 0 Met-10+ like-protein Raftlin PF15250.6 KFY00701.1 - 1.6 7.4 6.3 2.3 6.9 6.3 1.1 1 0 0 1 1 1 0 Raftlin Inositol_P PF00459.25 KFY00702.1 - 8.5e-66 222.2 0.0 9.8e-66 222.0 0.0 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family Antimicrobial_9 PF08104.11 KFY00702.1 - 0.09 12.8 0.0 0.18 11.8 0.0 1.5 1 0 0 1 1 1 0 Ponericin L family SMC_Nse1 PF07574.13 KFY00704.1 - 4.3e-72 242.1 0.5 5.5e-72 241.7 0.5 1.1 1 0 0 1 1 1 1 Nse1 non-SMC component of SMC5-6 complex zf-RING-like PF08746.11 KFY00704.1 - 7.3e-15 55.0 7.6 1.2e-14 54.3 7.6 1.4 1 0 0 1 1 1 1 RING-like domain zf-RING_9 PF13901.6 KFY00704.1 - 0.11 12.5 4.0 0.16 12.0 2.6 1.8 2 0 0 2 2 2 0 Putative zinc-RING and/or ribbon Vps4_C PF09336.10 KFY00704.1 - 0.11 12.5 0.1 13 5.8 0.0 2.5 2 0 0 2 2 2 0 Vps4 C terminal oligomerisation domain zf-RING_2 PF13639.6 KFY00704.1 - 0.13 12.6 7.2 0.22 11.9 7.2 1.4 1 0 0 1 1 1 0 Ring finger domain FANCL_C PF11793.8 KFY00704.1 - 1.1 9.5 5.2 3.5 7.9 5.2 1.9 1 1 0 1 1 1 0 FANCL C-terminal domain C1_2 PF03107.16 KFY00704.1 - 1.3 9.4 6.1 0.12 12.7 1.4 1.7 2 0 0 2 2 2 0 C1 domain Ysc84 PF04366.12 KFY00705.1 - 3.1e-44 149.8 0.1 5.5e-44 149.0 0.1 1.4 1 0 0 1 1 1 1 Las17-binding protein actin regulator WD40 PF00400.32 KFY00706.1 - 2.1e-10 41.0 6.8 0.00087 20.1 0.0 6.7 6 0 0 6 6 6 3 WD domain, G-beta repeat SPRY PF00622.28 KFY00706.1 - 1.4e-06 28.5 0.0 8.1e-05 22.7 0.0 2.6 2 0 0 2 2 2 1 SPRY domain Clr5 PF14420.6 KFY00707.1 - 0.012 15.8 0.1 0.017 15.3 0.1 1.2 1 0 0 1 1 1 0 Clr5 domain SQS_PSY PF00494.19 KFY00708.1 - 1.6e-36 126.2 0.0 2.3e-36 125.7 0.0 1.2 1 0 0 1 1 1 1 Squalene/phytoene synthase UAF_Rrn10 PF05234.11 KFY00710.1 - 0.00044 20.5 0.0 0.00062 20.0 0.0 1.2 1 0 0 1 1 1 1 UAF complex subunit Rrn10 WD40 PF00400.32 KFY00711.1 - 1.1e-22 79.9 18.0 1.9e-06 28.5 0.4 6.0 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFY00711.1 - 2.4e-11 43.8 0.5 0.012 15.9 0.0 4.2 3 2 0 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KFY00711.1 - 0.025 13.2 0.0 2.8 6.5 0.0 2.9 2 1 1 3 3 3 0 Nucleoporin Nup120/160 Ribosomal_L44 PF00935.19 KFY00714.1 - 2.6e-36 123.9 12.1 5.9e-36 122.8 12.1 1.6 1 0 0 1 1 1 1 Ribosomal protein L44 p450 PF00067.22 KFY00715.1 - 4.4e-45 154.3 0.0 1.1e-44 153.0 0.0 1.6 1 1 0 1 1 1 1 Cytochrome P450 Chromo PF00385.24 KFY00724.1 - 1.2 9.1 5.7 0.48 10.4 2.8 1.9 2 0 0 2 2 2 0 Chromo (CHRromatin Organisation MOdifier) domain ORC6 PF05460.13 KFY00725.1 - 0.48 9.6 6.1 0.66 9.2 6.1 1.2 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) Erv26 PF04148.13 KFY00726.1 - 5.6e-87 290.9 1.6 6.5e-87 290.7 1.6 1.0 1 0 0 1 1 1 1 Transmembrane adaptor Erv26 TMEM43 PF07787.12 KFY00726.1 - 0.35 10.2 3.4 0.52 9.6 3.4 1.3 1 0 0 1 1 1 0 Transmembrane protein 43 Methyltransf_11 PF08241.12 KFY00727.1 - 1.6e-10 41.5 0.0 3.1e-10 40.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KFY00727.1 - 9.7e-10 39.0 0.0 2.5e-09 37.7 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain WBS_methylT PF12589.8 KFY00727.1 - 5.6e-09 36.6 1.6 1.1e-08 35.7 1.6 1.4 1 0 0 1 1 1 1 Methyltransferase involved in Williams-Beuren syndrome Methyltransf_12 PF08242.12 KFY00727.1 - 0.0001 23.0 0.4 0.0006 20.5 0.0 2.5 3 1 0 3 3 3 1 Methyltransferase domain PCMT PF01135.19 KFY00727.1 - 0.00013 21.8 0.0 0.00026 20.8 0.0 1.5 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) CMAS PF02353.20 KFY00727.1 - 0.00052 19.4 0.0 0.0011 18.4 0.0 1.4 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_31 PF13847.6 KFY00727.1 - 0.003 17.3 0.0 0.0052 16.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KFY00727.1 - 0.007 16.2 0.0 0.013 15.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KFY00727.1 - 0.012 15.0 0.0 0.032 13.6 0.0 1.8 2 0 0 2 2 2 0 ubiE/COQ5 methyltransferase family APC_u5 PF16630.5 KFY00727.1 - 0.16 13.0 1.7 0.3 12.1 1.7 1.4 1 0 0 1 1 1 0 Unstructured region on APC between 1st and 2nd catenin-bdg motifs DUF1640 PF07798.11 KFY00728.1 - 1e-52 178.7 10.7 1.3e-52 178.4 10.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1640) CENP-O PF09496.10 KFY00728.1 - 0.006 16.6 0.6 0.01 15.9 0.6 1.4 1 0 0 1 1 1 1 Cenp-O kinetochore centromere component OEP PF02321.18 KFY00728.1 - 0.31 10.8 7.8 3.1 7.6 0.4 2.3 1 1 1 2 2 2 0 Outer membrane efflux protein MnmE_helical PF12631.7 KFY00728.1 - 0.61 10.2 5.0 0.28 11.3 2.6 1.6 2 0 0 2 2 2 0 MnmE helical domain cwf21 PF08312.12 KFY00728.1 - 1.1 9.5 5.9 1.1 9.4 4.3 2.0 2 1 0 2 2 2 0 cwf21 domain eIF2_C PF09173.11 KFY00729.1 - 8.4e-35 118.9 0.5 2.4e-34 117.4 0.5 1.8 1 0 0 1 1 1 1 Initiation factor eIF2 gamma, C terminal GTP_EFTU PF00009.27 KFY00729.1 - 3.7e-22 78.8 0.3 3.3e-21 75.7 0.3 2.2 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D2 PF03144.25 KFY00729.1 - 1.4e-10 41.4 0.5 3e-10 40.3 0.5 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 KFY00729.1 - 0.0051 16.9 0.0 0.012 15.7 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KFY00729.1 - 0.086 12.7 0.2 0.96 9.3 0.0 2.2 2 0 0 2 2 2 0 RsgA GTPase MMR_HSR1_Xtn PF16897.5 KFY00729.1 - 0.13 12.3 0.1 0.28 11.2 0.1 1.5 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain Rho_N PF07498.12 KFY00730.1 - 9e-05 22.3 0.2 0.33 10.9 0.0 3.3 3 0 0 3 3 3 2 Rho termination factor, N-terminal domain Bystin PF05291.11 KFY00731.1 - 4.4e-131 436.5 0.0 5.6e-131 436.1 0.0 1.1 1 0 0 1 1 1 1 Bystin bZIP_1 PF00170.21 KFY00733.1 - 0.0011 19.0 7.6 0.0018 18.4 7.6 1.2 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 KFY00733.1 - 0.0048 17.0 7.0 0.0076 16.3 7.0 1.3 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.17 KFY00733.1 - 0.02 15.4 1.6 0.033 14.7 1.6 1.3 1 0 0 1 1 1 0 bZIP Maf transcription factor DUF5470 PF17564.2 KFY00733.1 - 0.3 11.3 0.8 1.8 8.8 0.9 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF5470) Zn_clus PF00172.18 KFY00734.1 - 7.3e-08 32.4 10.8 7.3e-08 32.4 10.8 2.2 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 KFY00734.1 - 8.3e-08 31.4 8.3 1.4e-07 30.7 8.3 1.4 1 1 0 1 1 1 1 Fungal specific transcription factor domain p450 PF00067.22 KFY00736.1 - 1.3e-44 152.7 0.0 2.7e-44 151.7 0.0 1.4 1 1 0 1 1 1 1 Cytochrome P450 DUF3425 PF11905.8 KFY00737.1 - 6e-07 29.5 0.0 1.5e-06 28.2 0.0 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF3425) bZIP_1 PF00170.21 KFY00737.1 - 0.00059 19.9 14.3 0.0022 18.1 14.3 1.8 1 1 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 KFY00737.1 - 0.15 12.2 16.9 8.1 6.6 16.9 2.2 1 1 0 1 1 1 0 Basic region leucine zipper Glyco_hydro_16 PF00722.21 KFY00738.1 - 1e-42 145.6 1.8 1e-42 145.6 1.8 1.8 2 0 0 2 2 2 1 Glycosyl hydrolases family 16 RR_TM4-6 PF06459.12 KFY00738.1 - 0.28 11.0 3.5 0.39 10.5 3.5 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 SOG2 PF10428.9 KFY00738.1 - 0.52 9.5 19.7 0.71 9.0 19.7 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein RIFIN PF02009.16 KFY00738.1 - 1.7 8.4 4.8 2.3 8.0 4.8 1.2 1 0 0 1 1 1 0 Rifin DUF966 PF06136.13 KFY00738.1 - 2.4 7.8 12.4 3.2 7.4 12.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF966) PPP4R2 PF09184.11 KFY00738.1 - 2.7 7.5 10.9 3.9 7.0 10.9 1.2 1 0 0 1 1 1 0 PPP4R2 DUF1771 PF08590.10 KFY00744.1 - 7.7e-22 77.4 11.2 1.5e-21 76.5 11.2 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1771) Smr PF01713.21 KFY00744.1 - 3.1e-10 40.3 0.1 1.1e-09 38.5 0.1 2.0 1 0 0 1 1 1 1 Smr domain DUF4407 PF14362.6 KFY00744.1 - 0.046 13.1 2.3 0.061 12.7 2.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) adh_short PF00106.25 KFY00746.1 - 5.9e-27 94.4 0.0 8.1e-27 93.9 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KFY00746.1 - 5.1e-18 65.5 0.0 6.7e-18 65.1 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KFY00746.1 - 1.4e-06 28.3 0.0 2.3e-06 27.6 0.0 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 KFY00746.1 - 3.6e-05 23.7 0.0 9.3e-05 22.4 0.0 1.6 2 0 0 2 2 2 1 NAD(P)H-binding NmrA PF05368.13 KFY00746.1 - 0.003 17.1 0.0 0.0049 16.5 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family TrkA_N PF02254.18 KFY00746.1 - 0.006 16.8 0.3 0.024 14.9 0.1 1.9 2 0 0 2 2 2 1 TrkA-N domain Polysacc_synt_2 PF02719.15 KFY00746.1 - 0.0065 15.6 0.0 0.96 8.5 0.0 2.1 2 0 0 2 2 2 2 Polysaccharide biosynthesis protein GDP_Man_Dehyd PF16363.5 KFY00746.1 - 0.081 12.3 0.0 0.31 10.4 0.0 1.8 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase Fungal_trans_2 PF11951.8 KFY00747.1 - 1.6e-34 119.4 3.1 2.1e-34 119.0 3.1 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KFY00747.1 - 5.9e-07 29.5 8.8 1e-06 28.7 8.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Melibiase PF02065.18 KFY00748.1 - 6.7e-152 505.4 0.0 8.8e-152 505.0 0.0 1.1 1 0 0 1 1 1 1 Melibiase Glyco_hydro_36N PF16875.5 KFY00748.1 - 1.4e-79 267.2 0.0 2.3e-79 266.5 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 36 N-terminal domain GHL10 PF02638.15 KFY00748.1 - 9.5e-06 24.9 0.0 1.6e-05 24.2 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase-like 10 Clr5 PF14420.6 KFY00750.1 - 1.8e-08 34.4 0.1 1e-07 32.0 0.1 2.2 2 0 0 2 2 2 1 Clr5 domain DUF1720 PF08226.11 KFY00750.1 - 8 6.9 10.2 1.4 9.4 3.1 2.9 2 1 0 2 2 2 0 Domain of unknown function (DUF1720) Orn_Arg_deC_N PF02784.16 KFY00751.1 - 1.8e-80 269.9 0.0 2.5e-80 269.4 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.22 KFY00751.1 - 2.6e-19 69.3 0.0 3e-19 69.0 0.0 1.3 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain AP_endonuc_2 PF01261.24 KFY00751.1 - 0.0029 17.1 0.0 0.021 14.3 0.0 2.1 2 0 0 2 2 2 1 Xylose isomerase-like TIM barrel M16C_assoc PF08367.11 KFY00752.1 - 2.8e-83 278.9 0.2 4.6e-83 278.2 0.2 1.4 1 0 0 1 1 1 1 Peptidase M16C associated Peptidase_M16_C PF05193.21 KFY00752.1 - 1.2e-32 113.5 0.0 2.3e-22 79.9 0.0 3.4 4 0 0 4 4 4 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 KFY00752.1 - 3.5e-09 36.8 0.0 2e-08 34.3 0.0 2.3 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Taxilin PF09728.9 KFY00753.1 - 3.8e-95 318.6 59.9 6e-95 318.0 59.9 1.3 1 0 0 1 1 1 1 Myosin-like coiled-coil protein Cas6b_C PF17262.2 KFY00753.1 - 5 7.3 7.4 0.49 10.5 1.6 2.3 2 0 0 2 2 2 0 Cas6b C-terminal domain TMF_TATA_bd PF12325.8 KFY00753.1 - 7.1 6.9 56.6 3.2 8.0 10.6 4.3 2 2 2 4 4 4 0 TATA element modulatory factor 1 TATA binding Histone_HNS PF00816.21 KFY00754.1 - 0.014 16.2 1.0 0.058 14.2 1.0 2.1 1 0 0 1 1 1 0 H-NS histone family DUF4120 PF13496.6 KFY00754.1 - 0.098 13.0 0.0 0.27 11.6 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4120) NMO PF03060.15 KFY00755.1 - 1.9e-54 185.3 2.7 2.4e-54 184.9 2.7 1.1 1 0 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.25 KFY00755.1 - 3.9e-08 32.7 2.6 3.9e-08 32.7 2.6 1.6 2 0 0 2 2 2 1 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.18 KFY00755.1 - 0.026 13.5 5.2 0.047 12.7 5.2 1.4 1 0 0 1 1 1 0 FMN-dependent dehydrogenase zf-Tim10_DDP PF02953.15 KFY00760.1 - 7e-20 70.4 2.6 1.1e-19 69.8 2.6 1.3 1 0 0 1 1 1 1 Tim10/DDP family zinc finger DUF842 PF05811.13 KFY00760.1 - 0.036 13.8 2.5 1.1 9.0 0.2 2.1 1 1 0 1 1 1 0 Eukaryotic protein of unknown function (DUF842) RhoGAP PF00620.27 KFY00761.1 - 7.3e-40 136.3 0.0 1e-39 135.8 0.0 1.2 1 0 0 1 1 1 1 RhoGAP domain Pkinase PF00069.25 KFY00780.1 - 3e-26 92.4 0.0 3.7e-26 92.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFY00780.1 - 8e-14 51.5 0.0 1.1e-13 51.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KFY00780.1 - 4.1e-09 35.7 0.0 7.1e-09 34.9 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 KFY00780.1 - 0.00021 21.3 0.0 0.0015 18.5 0.0 2.1 1 1 0 2 2 2 1 Phosphotransferase enzyme family Adaptin_N PF01602.20 KFY00781.1 - 2.5e-107 359.6 0.2 3.2e-107 359.3 0.2 1.1 1 0 0 1 1 1 1 Adaptin N terminal region COP-gamma_platf PF08752.10 KFY00781.1 - 1e-58 197.8 1.5 2e-58 196.8 1.5 1.5 1 0 0 1 1 1 1 Coatomer gamma subunit appendage platform subdomain Coatomer_g_Cpla PF16381.5 KFY00781.1 - 3.3e-35 120.7 0.1 8.6e-35 119.4 0.1 1.8 1 0 0 1 1 1 1 Coatomer subunit gamma-1 C-terminal appendage platform HEAT_2 PF13646.6 KFY00781.1 - 1.2e-18 67.3 0.5 2.2e-12 47.2 0.0 5.3 2 1 3 5 5 5 2 HEAT repeats Cnd1 PF12717.7 KFY00781.1 - 1.3e-06 28.5 7.4 0.053 13.6 0.1 4.2 3 1 1 4 4 4 2 non-SMC mitotic condensation complex subunit 1 HEAT_PBS PF03130.16 KFY00781.1 - 0.0024 18.4 0.2 4.5 8.2 0.0 4.1 3 0 0 3 3 3 1 PBS lyase HEAT-like repeat CLASP_N PF12348.8 KFY00781.1 - 0.0084 15.7 0.7 0.13 11.8 0.0 2.7 3 0 0 3 3 3 1 CLASP N terminal HEAT PF02985.22 KFY00781.1 - 0.033 14.4 6.5 1.7 9.1 0.2 4.8 4 0 0 4 4 4 0 HEAT repeat MRP-S35 PF10246.9 KFY00781.1 - 0.077 13.0 0.0 0.21 11.6 0.0 1.7 1 0 0 1 1 1 0 Mitochondrial ribosomal protein MRP-S35 CDP-OH_P_transf PF01066.21 KFY00782.1 - 4.9e-17 62.5 0.1 4.9e-17 62.5 0.1 3.3 3 1 0 3 3 3 1 CDP-alcohol phosphatidyltransferase DUF5313 PF17240.2 KFY00782.1 - 0.28 11.6 1.2 5.8 7.4 0.2 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF5313) Cupin_2 PF07883.11 KFY00792.1 - 0.12 12.1 0.1 0.19 11.4 0.1 1.2 1 0 0 1 1 1 0 Cupin domain Cellulase PF00150.18 KFY00800.1 - 2.1e-51 175.0 0.2 2.6e-51 174.7 0.2 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) CBM_1 PF00734.18 KFY00800.1 - 1e-12 47.7 16.2 1e-12 47.7 16.2 2.7 3 0 0 3 3 3 1 Fungal cellulose binding domain HERV-K_REC PF15695.5 KFY00800.1 - 0.12 12.4 0.0 0.26 11.3 0.0 1.6 1 0 0 1 1 1 0 Rec (regulator of expression encoded by corf) of HERV-K-113 AA_permease PF00324.21 KFY00802.1 - 3.9e-137 457.7 36.9 4.7e-137 457.5 36.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 KFY00802.1 - 4.6e-35 121.3 40.7 5.6e-35 121.0 40.7 1.1 1 0 0 1 1 1 1 Amino acid permease Glyco_hydro_79C PF16862.5 KFY00803.1 - 1.4e-13 51.6 0.0 2.3e-13 50.9 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 79 C-terminal beta domain RGS PF00615.19 KFY00811.1 - 2.7e-33 114.7 0.0 5.7e-33 113.7 0.0 1.6 1 0 0 1 1 1 1 Regulator of G protein signaling domain DEP PF00610.21 KFY00811.1 - 6.7e-21 74.1 0.0 5.1e-17 61.7 0.0 3.2 3 0 0 3 3 3 2 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) zf_PR_Knuckle PF18445.1 KFY00811.1 - 9.5e-05 22.1 0.1 0.0017 18.1 0.0 2.4 2 0 0 2 2 2 1 PR zinc knuckle motif Fungal_trans PF04082.18 KFY00829.1 - 6.2e-13 48.4 0.1 1e-12 47.7 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Phospholip_A2_3 PF09056.11 KFY00830.1 - 6.2e-40 136.3 5.7 8.4e-40 135.9 5.7 1.2 1 0 0 1 1 1 1 Prokaryotic phospholipase A2 GOLGA2L5 PF15070.6 KFY00830.1 - 0.21 10.2 0.0 0.24 10.0 0.0 1.1 1 0 0 1 1 1 0 Putative golgin subfamily A member 2-like protein 5 MMR_HSR1 PF01926.23 KFY00831.1 - 9.1e-08 32.2 0.4 2.2e-07 31.0 0.1 1.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase Dynamin_N PF00350.23 KFY00831.1 - 1.8e-05 24.9 9.5 0.015 15.3 0.3 3.0 3 1 1 4 4 4 2 Dynamin family AIG1 PF04548.16 KFY00831.1 - 0.00032 20.1 0.1 0.00054 19.4 0.1 1.3 1 0 0 1 1 1 1 AIG1 family FeoB_N PF02421.18 KFY00831.1 - 0.00088 18.8 0.0 0.0018 17.8 0.0 1.5 1 0 0 1 1 1 1 Ferrous iron transport protein B IIGP PF05049.13 KFY00831.1 - 0.008 15.3 0.1 0.016 14.3 0.1 1.4 1 0 0 1 1 1 1 Interferon-inducible GTPase (IIGP) RsgA_GTPase PF03193.16 KFY00831.1 - 0.037 13.9 0.8 0.17 11.8 0.8 2.0 1 1 0 1 1 1 0 RsgA GTPase Septin PF00735.18 KFY00831.1 - 0.038 13.3 0.2 0.14 11.4 0.2 1.9 1 1 0 1 1 1 0 Septin AAA_22 PF13401.6 KFY00831.1 - 0.082 13.2 0.0 0.24 11.6 0.0 1.8 2 0 0 2 2 2 0 AAA domain CEP19 PF14933.6 KFY00831.1 - 0.11 12.8 0.5 1.8 8.9 0.0 2.6 2 0 0 2 2 2 0 CEP19-like protein ABC_tran PF00005.27 KFY00831.1 - 1.2 9.6 4.4 0.51 10.9 0.2 2.4 3 0 0 3 3 3 0 ABC transporter CAP_N PF01213.19 KFY00831.1 - 1.6 8.2 4.8 0.88 9.0 1.4 2.2 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal MF_alpha_N PF05436.11 KFY00832.1 - 0.18 11.7 0.1 0.28 11.1 0.1 1.3 1 0 0 1 1 1 0 Mating factor alpha precursor N-terminus Abhydrolase_3 PF07859.13 KFY00833.1 - 9.1e-26 91.0 0.0 1.1e-25 90.7 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 KFY00833.1 - 1e-07 31.2 0.0 1.6e-07 30.5 0.0 1.2 1 0 0 1 1 1 1 Steryl acetyl hydrolase Hydrolase_4 PF12146.8 KFY00833.1 - 0.026 13.8 0.0 2.5 7.3 0.0 2.3 2 0 0 2 2 2 0 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 KFY00833.1 - 0.12 11.8 0.0 0.25 10.8 0.0 1.7 1 1 0 1 1 1 0 Prolyl oligopeptidase family COesterase PF00135.28 KFY00833.1 - 0.16 10.8 0.0 5.9 5.6 0.0 2.1 2 0 0 2 2 2 0 Carboxylesterase family OCRE PF17780.1 KFY00839.1 - 0.0017 18.3 3.9 0.014 15.5 0.7 2.7 2 0 0 2 2 2 1 OCRE domain SpoIIIAH PF12685.7 KFY00839.1 - 0.04 13.7 0.8 0.062 13.1 0.8 1.2 1 0 0 1 1 1 0 SpoIIIAH-like protein Podoplanin PF05808.11 KFY00839.1 - 0.047 13.8 0.4 0.088 12.9 0.4 1.4 1 0 0 1 1 1 0 Podoplanin Macoilin PF09726.9 KFY00839.1 - 2.2 6.8 3.0 3.2 6.2 3.0 1.1 1 0 0 1 1 1 0 Macoilin family BatA PF07584.11 KFY00839.1 - 6 7.3 5.0 38 4.8 0.1 2.5 3 0 0 3 3 3 0 Aerotolerance regulator N-terminal Glyco_hydro_18 PF00704.28 KFY00840.1 - 1.8e-44 152.8 0.0 2.7e-44 152.2 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Chitin_bind_1 PF00187.19 KFY00840.1 - 0.00037 20.9 8.4 0.00037 20.9 8.4 2.6 2 1 0 2 2 2 1 Chitin recognition protein Zn_clus PF00172.18 KFY00843.1 - 1.2e-07 31.7 7.9 2e-07 31.0 7.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 KFY00843.1 - 0.00025 20.0 1.3 0.00081 18.3 0.0 2.0 1 1 1 2 2 2 1 Fungal specific transcription factor domain DUF2306 PF10067.9 KFY00844.1 - 1.4e-14 54.6 13.5 2.8e-14 53.5 13.5 1.6 1 0 0 1 1 1 1 Predicted membrane protein (DUF2306) Glyco_transf_28 PF03033.20 KFY00846.1 - 3.7e-17 62.6 1.0 6.9e-12 45.6 0.0 2.9 3 0 0 3 3 3 2 Glycosyltransferase family 28 N-terminal domain UDPGT PF00201.18 KFY00846.1 - 1.1e-06 27.7 0.0 2.1e-06 26.8 0.0 1.3 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase UIM PF02809.20 KFY00846.1 - 6.7e-05 22.5 1.4 0.22 11.5 0.0 3.7 3 0 0 3 3 3 1 Ubiquitin interaction motif Glyco_tran_28_C PF04101.16 KFY00846.1 - 0.006 16.6 0.1 1.2 9.0 0.0 3.3 3 0 0 3 3 3 1 Glycosyltransferase family 28 C-terminal domain VPS13_C PF16909.5 KFY00846.1 - 0.08 12.7 0.2 0.25 11.1 0.2 1.8 1 0 0 1 1 1 0 Vacuolar-sorting-associated 13 protein C-terminal Zn_clus PF00172.18 KFY00847.1 - 7.6e-07 29.2 10.2 7.6e-07 29.2 10.2 1.7 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 KFY00847.1 - 4e-06 25.9 0.4 8.3e-06 24.9 0.1 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain BTAD PF03704.17 KFY00847.1 - 0.14 12.6 0.5 6.8 7.1 0.1 2.4 2 0 0 2 2 2 0 Bacterial transcriptional activator domain TPR_12 PF13424.6 KFY00848.1 - 1.3e-33 115.1 14.3 2.5e-11 43.7 0.1 7.0 3 1 1 6 6 6 5 Tetratricopeptide repeat TPR_10 PF13374.6 KFY00848.1 - 4.9e-24 83.5 6.4 0.00027 20.7 0.0 8.3 8 1 0 8 8 8 6 Tetratricopeptide repeat TPR_MalT PF17874.1 KFY00848.1 - 2.4e-09 37.1 9.4 1.5e-07 31.1 1.0 3.2 1 1 1 3 3 3 2 MalT-like TPR region TPR_7 PF13176.6 KFY00848.1 - 5e-07 29.3 6.4 0.83 9.8 0.1 6.2 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_19 PF14559.6 KFY00848.1 - 6.5e-06 26.6 3.6 0.48 11.0 0.1 4.7 3 1 2 5 5 5 2 Tetratricopeptide repeat TPR_16 PF13432.6 KFY00848.1 - 1.8e-05 25.3 0.0 0.29 11.8 0.0 4.9 4 1 0 4 4 4 1 Tetratricopeptide repeat TPR_8 PF13181.6 KFY00848.1 - 0.00058 19.9 8.2 1.5 9.3 0.0 5.9 7 0 0 7 7 6 2 Tetratricopeptide repeat NB-ARC PF00931.22 KFY00848.1 - 0.0013 17.9 0.0 0.0058 15.8 0.0 2.0 1 1 0 1 1 1 1 NB-ARC domain TPR_14 PF13428.6 KFY00848.1 - 0.0014 19.2 4.9 0.68 10.9 0.1 5.1 6 0 0 6 6 4 1 Tetratricopeptide repeat AAA_16 PF13191.6 KFY00848.1 - 0.0044 17.4 0.3 0.033 14.6 0.0 2.6 2 1 1 3 3 2 1 AAA ATPase domain CbiA PF01656.23 KFY00848.1 - 0.0066 16.5 0.0 0.017 15.2 0.0 1.6 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain PPR PF01535.20 KFY00848.1 - 0.011 16.0 4.3 15 6.1 0.1 4.6 5 0 0 5 5 5 0 PPR repeat TPR_1 PF00515.28 KFY00848.1 - 0.012 15.4 2.8 17 5.4 0.0 5.3 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_4 PF07721.14 KFY00848.1 - 0.013 16.1 0.1 1.4 9.8 0.0 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.17 KFY00848.1 - 0.025 14.7 10.5 6.1 7.2 0.0 6.7 8 0 0 8 8 7 0 Tetratricopeptide repeat ATPase_2 PF01637.18 KFY00848.1 - 0.038 13.9 0.0 0.075 12.9 0.0 1.5 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea ANAPC3 PF12895.7 KFY00848.1 - 0.11 12.8 0.1 5.6 7.3 0.0 3.6 4 0 0 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.6 KFY00849.1 - 9.7e-35 118.7 9.1 7e-11 42.3 0.2 5.6 2 2 4 6 6 6 5 Tetratricopeptide repeat TPR_10 PF13374.6 KFY00849.1 - 2.1e-30 103.7 6.6 8.7e-07 28.6 0.0 6.7 7 0 0 7 7 7 5 Tetratricopeptide repeat TPR_7 PF13176.6 KFY00849.1 - 1.4e-12 46.7 0.2 0.0055 16.6 0.0 4.4 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.17 KFY00849.1 - 1.1e-09 37.6 1.6 0.14 12.4 0.0 5.1 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_1 PF00515.28 KFY00849.1 - 1.3e-08 34.3 0.6 0.0058 16.4 0.0 3.9 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.6 KFY00849.1 - 7.3e-08 32.0 1.7 0.15 12.3 0.1 4.0 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 KFY00849.1 - 6.2e-07 29.7 1.3 0.88 10.6 0.0 5.4 5 2 1 6 6 6 1 Tetratricopeptide repeat TPR_MalT PF17874.1 KFY00849.1 - 1.3e-06 28.1 0.5 0.00077 18.9 0.0 2.2 1 1 1 2 2 2 2 MalT-like TPR region TPR_16 PF13432.6 KFY00849.1 - 2.3e-06 28.2 1.0 1.1 9.9 0.0 4.4 2 2 1 3 3 3 2 Tetratricopeptide repeat RPN7 PF10602.9 KFY00849.1 - 0.053 13.2 0.0 3.8 7.2 0.0 2.4 2 0 0 2 2 2 0 26S proteasome subunit RPN7 DUF2989 PF11207.8 KFY00849.1 - 0.085 12.6 0.2 2.1 8.1 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2989) TPR_17 PF13431.6 KFY00849.1 - 0.088 13.2 0.7 8.3 7.0 0.1 3.5 4 0 0 4 4 4 0 Tetratricopeptide repeat PPR PF01535.20 KFY00849.1 - 0.15 12.4 0.1 19 5.7 0.0 3.4 3 0 0 3 3 2 0 PPR repeat TPR_4 PF07721.14 KFY00849.1 - 0.18 12.5 1.0 20 6.2 0.0 4.5 6 0 0 6 6 5 0 Tetratricopeptide repeat DUF1897 PF09005.10 KFY00849.1 - 1.8 8.1 4.6 1.7 8.2 0.1 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF1897) Carn_acyltransf PF00755.20 KFY00850.1 - 2.6e-209 696.7 0.0 4.1e-209 696.1 0.0 1.3 1 1 0 1 1 1 1 Choline/Carnitine o-acyltransferase PHD PF00628.29 KFY00853.1 - 9.5e-09 35.0 6.4 2.3e-08 33.8 6.4 1.7 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.6 KFY00853.1 - 0.0072 15.9 3.3 0.015 14.9 3.3 1.5 1 0 0 1 1 1 1 PHD-finger LMBR1 PF04791.16 KFY00853.1 - 4.5 6.1 6.7 5.2 5.9 6.7 1.3 1 0 0 1 1 1 0 LMBR1-like membrane protein TPR_11 PF13414.6 KFY00854.1 - 4.2e-06 26.3 2.4 0.022 14.5 2.1 3.2 3 0 0 3 3 3 2 TPR repeat TPR_19 PF14559.6 KFY00854.1 - 9.5e-06 26.0 3.1 0.68 10.5 0.0 5.0 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_17 PF13431.6 KFY00854.1 - 0.00031 20.9 0.2 0.066 13.6 0.0 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.6 KFY00854.1 - 0.00047 20.7 14.0 8.2 7.5 0.1 6.5 5 0 0 5 5 5 2 Tetratricopeptide repeat Mak10 PF04112.13 KFY00854.1 - 0.052 13.1 0.3 1.3 8.5 0.0 2.6 2 0 0 2 2 2 0 Mak10 subunit, NatC N(alpha)-terminal acetyltransferase Nucleo_P87 PF07267.11 KFY00854.1 - 0.48 9.2 12.5 0.037 12.9 5.5 2.1 2 0 0 2 2 2 0 Nucleopolyhedrovirus capsid protein P87 TPR_1 PF00515.28 KFY00854.1 - 1.5 8.8 11.2 7.5 6.6 0.7 5.6 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_16 PF13432.6 KFY00854.1 - 6.1 7.6 16.8 3.1 8.5 0.0 5.0 5 0 0 5 5 5 0 Tetratricopeptide repeat Cellulase PF00150.18 KFY00855.1 - 4.1e-41 141.3 6.9 3.6e-40 138.1 4.4 2.1 2 0 0 2 2 2 2 Cellulase (glycosyl hydrolase family 5) CBM_X2 PF03442.14 KFY00855.1 - 6.2e-23 80.7 6.9 3.8e-20 71.8 3.6 3.4 2 1 0 2 2 2 2 Carbohydrate binding domain X2 Transferase PF02458.15 KFY00857.1 - 5.9e-28 97.7 0.0 1.5e-26 93.1 0.0 2.0 2 0 0 2 2 2 2 Transferase family RHH_1 PF01402.21 KFY00857.1 - 0.12 12.4 0.5 7 6.7 0.1 2.5 2 0 0 2 2 2 0 Ribbon-helix-helix protein, copG family Abhydrolase_3 PF07859.13 KFY00858.1 - 1.5e-41 142.6 0.0 1.5e-40 139.4 0.0 2.3 2 1 0 2 2 2 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 KFY00858.1 - 0.005 15.7 0.0 0.071 12.0 0.0 2.0 2 0 0 2 2 2 1 Steryl acetyl hydrolase TMEM154 PF15102.6 KFY00859.1 - 0.059 13.3 0.3 0.13 12.2 0.1 1.7 1 1 1 2 2 2 0 TMEM154 protein family DUF2615 PF11027.8 KFY00859.1 - 0.18 11.9 0.1 0.18 11.9 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2615) ChAPs PF09295.10 KFY00860.1 - 6.1e-152 506.2 0.0 7.5e-152 505.9 0.0 1.1 1 0 0 1 1 1 1 ChAPs (Chs5p-Arf1p-binding proteins) TPR_14 PF13428.6 KFY00860.1 - 6.6e-05 23.4 1.3 4.4 8.4 0.0 5.1 3 2 1 4 4 4 1 Tetratricopeptide repeat TPR_19 PF14559.6 KFY00860.1 - 0.00031 21.2 0.0 1.8 9.2 0.0 2.9 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.17 KFY00860.1 - 0.00058 19.8 0.5 4.7 7.6 1.0 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_9 PF13371.6 KFY00860.1 - 0.0024 18.0 1.9 0.049 13.8 0.0 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.6 KFY00860.1 - 0.046 13.8 0.6 1.1 9.4 0.1 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat Bac_rhamnosid6H PF17389.2 KFY00862.1 - 1.1e-10 41.3 0.0 4.7e-10 39.2 0.0 1.9 3 0 0 3 3 3 1 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain Bac_rhamnosid_C PF17390.2 KFY00862.1 - 5.3e-06 26.1 0.0 1e-05 25.2 0.0 1.5 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase C-terminal domain DUF608 PF04685.13 KFY00862.1 - 4.9e-05 22.7 0.6 7.2e-05 22.1 0.6 1.2 1 0 0 1 1 1 1 Glycosyl-hydrolase family 116, catalytic region Trehalase PF01204.18 KFY00862.1 - 0.00026 20.0 0.1 0.00037 19.5 0.1 1.1 1 0 0 1 1 1 1 Trehalase Glyco_hydro_36 PF17167.4 KFY00862.1 - 0.014 14.1 0.0 0.024 13.3 0.0 1.3 1 0 0 1 1 1 0 Glycosyl hydrolase 36 superfamily, catalytic domain Bac_rhamnosid PF05592.11 KFY00862.1 - 0.043 13.8 0.1 0.1 12.6 0.1 1.7 1 1 0 1 1 1 0 Bacterial alpha-L-rhamnosidase concanavalin-like domain FAD_binding_3 PF01494.19 KFY00863.1 - 1.4e-11 44.3 0.1 4e-11 42.8 0.1 1.7 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.24 KFY00863.1 - 2.8e-05 23.9 0.0 6.5e-05 22.7 0.0 1.6 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KFY00863.1 - 6.4e-05 22.3 0.0 0.00044 19.6 0.0 2.3 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KFY00863.1 - 0.00049 20.3 0.0 0.0012 19.0 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 KFY00863.1 - 0.0005 20.6 0.0 0.0021 18.6 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase CoA_transf_3 PF02515.17 KFY00863.1 - 0.0021 17.3 0.0 0.003 16.7 0.0 1.2 1 0 0 1 1 1 1 CoA-transferase family III ApbA PF02558.16 KFY00863.1 - 0.0084 15.8 0.0 0.014 15.1 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Pyr_redox_3 PF13738.6 KFY00863.1 - 0.073 12.3 0.0 0.18 11.0 0.0 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Fungal_trans PF04082.18 KFY00864.1 - 2.5e-09 36.6 0.0 4.7e-09 35.7 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KFY00864.1 - 2.8e-07 30.5 10.1 4.7e-07 29.8 10.1 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF1116 PF06545.11 KFY00864.1 - 0.1 12.1 0.4 0.18 11.3 0.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1116) Glyco_hydro_76 PF03663.14 KFY00865.1 - 5.1e-35 121.7 18.2 6.7e-35 121.3 18.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Glyco_hydro_88 PF07470.13 KFY00865.1 - 3.5e-05 23.0 0.2 0.0075 15.4 0.0 2.2 2 0 0 2 2 2 2 Glycosyl Hydrolase Family 88 Lactonase PF10282.9 KFY00867.1 - 5.6e-84 282.3 0.0 6.9e-84 282.0 0.0 1.0 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller Prim-Pol PF09250.11 KFY00867.1 - 0.13 12.6 0.0 0.85 10.0 0.0 2.0 2 0 0 2 2 2 0 Bifunctional DNA primase/polymerase, N-terminal MIP PF00230.20 KFY00868.1 - 4.1e-25 88.8 11.8 8.1e-25 87.9 11.8 1.5 1 1 0 1 1 1 1 Major intrinsic protein CRM1_repeat_2 PF18784.1 KFY00869.1 - 0.15 11.7 0.1 0.31 10.7 0.1 1.5 1 0 0 1 1 1 0 CRM1 / Exportin repeat 2 Glyco_hydro_35 PF01301.19 KFY00870.1 - 6.4e-90 302.0 0.2 8e-90 301.7 0.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 Glyco_hydro_42 PF02449.15 KFY00870.1 - 3.3e-11 43.1 0.2 1.2e-10 41.3 0.2 1.7 1 1 0 1 1 1 1 Beta-galactosidase BetaGal_dom4_5 PF13364.6 KFY00870.1 - 4.7e-05 23.9 0.0 0.013 16.1 0.0 3.2 3 0 0 3 3 3 1 Beta-galactosidase jelly roll domain NAD_binding_10 PF13460.6 KFY00871.1 - 0.00032 20.7 0.0 0.00052 19.9 0.0 1.4 1 1 0 1 1 1 1 NAD(P)H-binding DapB_N PF01113.20 KFY00871.1 - 0.12 12.5 0.0 0.22 11.7 0.0 1.5 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus K_oxygenase PF13434.6 KFY00871.1 - 0.15 11.1 0.0 0.21 10.7 0.0 1.1 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) TPR_10 PF13374.6 KFY00872.1 - 3.8e-27 93.4 1.3 1.2e-11 44.1 0.0 3.1 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_12 PF13424.6 KFY00872.1 - 6.2e-22 77.7 6.0 9.4e-12 45.1 0.4 2.0 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.28 KFY00872.1 - 7.4e-08 31.9 6.7 0.044 13.6 0.3 3.3 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 KFY00872.1 - 7.5e-07 28.8 5.8 0.061 13.5 0.1 3.2 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_19 PF14559.6 KFY00872.1 - 8.2e-07 29.4 2.3 0.15 12.6 0.0 3.0 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.6 KFY00872.1 - 1.2e-06 28.1 3.5 0.01 15.8 0.1 3.5 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_17 PF13431.6 KFY00872.1 - 0.0011 19.2 6.0 1.9 9.0 0.5 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_4 PF07721.14 KFY00872.1 - 0.0013 19.2 0.0 15 6.5 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.6 KFY00872.1 - 0.0016 18.5 4.8 0.4 11.0 0.2 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_3 PF07720.12 KFY00872.1 - 0.008 16.2 4.7 1.2 9.2 0.2 3.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 KFY00872.1 - 0.0081 16.8 0.9 13 6.6 0.0 3.1 2 1 1 3 3 3 0 Tetratricopeptide repeat ANAPC3 PF12895.7 KFY00872.1 - 0.02 15.1 0.9 9.7 6.5 0.3 2.7 2 1 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_20 PF14561.6 KFY00872.1 - 0.06 13.7 1.0 1.5 9.2 0.2 2.8 1 1 1 2 2 2 0 Tetratricopeptide repeat MCM PF00493.23 KFY00872.1 - 0.11 11.6 0.1 17 4.4 0.0 2.6 2 1 1 3 3 3 0 MCM P-loop domain PPR PF01535.20 KFY00872.1 - 0.15 12.4 0.2 4.9 7.6 0.0 2.9 3 1 1 4 4 4 0 PPR repeat zf-CCHC_6 PF15288.6 KFY00874.1 - 0.013 15.3 2.2 0.032 14.1 2.2 1.7 1 0 0 1 1 1 0 Zinc knuckle VWD PF00094.25 KFY00874.1 - 0.025 14.8 0.4 0.031 14.6 0.4 1.1 1 0 0 1 1 1 0 von Willebrand factor type D domain zf-CCHC_4 PF14392.6 KFY00874.1 - 0.11 12.2 1.1 0.2 11.4 1.1 1.5 1 0 0 1 1 1 0 Zinc knuckle DCA16 PF15349.6 KFY00875.1 - 0.095 12.2 3.7 0.14 11.7 3.7 1.2 1 0 0 1 1 1 0 DDB1- and CUL4-associated factor 16 Ank_2 PF12796.7 KFY00876.1 - 0.085 13.5 0.0 0.67 10.6 0.0 2.1 2 0 0 2 2 2 0 Ankyrin repeats (3 copies) Hexokinase_2 PF03727.16 KFY00877.1 - 8.2e-29 100.7 0.1 9.2e-29 100.6 0.1 1.0 1 0 0 1 1 1 1 Hexokinase Glyco_transf_8 PF01501.20 KFY00878.1 - 6.6e-20 71.7 1.8 7.4e-19 68.3 1.8 2.0 1 1 0 1 1 1 1 Glycosyl transferase family 8 Mannosyl_trans3 PF11051.8 KFY00878.1 - 0.071 12.4 0.0 0.12 11.7 0.0 1.2 1 0 0 1 1 1 0 Mannosyltransferase putative Cation_efflux PF01545.21 KFY00879.1 - 9.4e-17 61.4 9.9 1.3e-16 60.9 9.9 1.2 1 0 0 1 1 1 1 Cation efflux family ZT_dimer PF16916.5 KFY00879.1 - 1.1e-08 35.0 0.3 3.3e-08 33.5 0.3 1.7 1 0 0 1 1 1 1 Dimerisation domain of Zinc Transporter zf-rbx1 PF12678.7 KFY00879.1 - 1.8e-08 34.5 4.1 1e-07 32.1 4.1 2.3 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_2 PF13639.6 KFY00879.1 - 1.2e-07 32.0 2.0 1.2e-07 32.0 2.0 2.6 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4 PF00097.25 KFY00879.1 - 7.8e-06 25.7 0.3 2.4e-05 24.1 0.3 1.9 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KFY00879.1 - 3.8e-05 23.5 1.1 0.00033 20.6 0.2 2.4 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 KFY00879.1 - 4.1e-05 23.5 0.2 4.1e-05 23.5 0.2 2.2 2 1 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 KFY00879.1 - 4.5e-05 23.2 5.0 0.00021 21.1 1.0 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KFY00879.1 - 0.00069 19.4 2.8 0.00069 19.4 2.8 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 KFY00879.1 - 0.0014 18.2 0.9 0.0037 16.9 0.9 1.6 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type Prok-RING_4 PF14447.6 KFY00879.1 - 0.0018 18.1 1.0 0.0018 18.1 1.0 1.8 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-ANAPC11 PF12861.7 KFY00879.1 - 0.02 15.0 1.4 0.097 12.7 0.4 2.4 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_4 PF15227.6 KFY00879.1 - 0.091 12.9 1.0 0.26 11.5 1.0 1.8 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.6 KFY00879.1 - 0.13 12.1 0.8 0.37 10.6 0.8 1.7 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain DUF3455 PF11937.8 KFY00881.1 - 3.1e-44 151.2 0.1 3.9e-44 150.8 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3455) DUF2990 PF11693.8 KFY00881.1 - 0.0052 16.9 4.1 0.0084 16.3 1.7 2.6 2 1 0 2 2 2 1 Protein of unknown function (DUF2990) SPT_ssu-like PF11779.8 KFY00889.1 - 1.6e-05 24.4 2.0 2.2e-05 24.0 2.0 1.2 1 0 0 1 1 1 1 Small subunit of serine palmitoyltransferase-like CENP-I PF07778.11 KFY00890.1 - 4.5e-23 81.7 0.0 5.1e-13 48.6 0.0 2.6 1 1 0 2 2 2 2 Mis6 Sacchrp_dh_C PF16653.5 KFY00893.1 - 6.8e-97 324.7 0.0 1.3e-96 323.8 0.0 1.4 1 1 0 1 1 1 1 Saccharopine dehydrogenase C-terminal domain Sacchrp_dh_NADP PF03435.18 KFY00893.1 - 4.3e-26 91.7 2.0 7e-26 91.0 2.0 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Shikimate_DH PF01488.20 KFY00893.1 - 1.5e-08 34.8 0.2 2.6e-08 34.0 0.2 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase IlvN PF07991.12 KFY00893.1 - 0.0004 20.0 2.7 0.00092 18.8 1.2 2.4 2 1 0 2 2 2 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain NAD_binding_10 PF13460.6 KFY00893.1 - 0.00069 19.6 3.4 0.0013 18.6 3.5 1.5 1 1 0 1 1 1 1 NAD(P)H-binding GFO_IDH_MocA PF01408.22 KFY00893.1 - 0.0091 16.8 0.3 0.017 15.9 0.3 1.5 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold NAD_binding_3 PF03447.16 KFY00893.1 - 0.011 16.3 1.5 0.02 15.6 1.5 1.4 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain NAD_binding_7 PF13241.6 KFY00893.1 - 0.12 12.9 0.4 0.22 12.0 0.4 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding TRAPPC9-Trs120 PF08626.11 KFY00895.1 - 0 1457.3 0.0 0 1457.1 0.0 1.0 1 0 0 1 1 1 1 Transport protein Trs120 or TRAPPC9, TRAPP II complex subunit ASH PF15780.5 KFY00895.1 - 0.0078 16.4 0.0 0.22 11.7 0.0 2.5 2 0 0 2 2 2 1 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin MMM1 PF10296.9 KFY00896.1 - 2.9e-141 470.3 0.0 2.5e-140 467.2 0.0 2.1 1 1 0 1 1 1 1 Maintenance of mitochondrial morphology protein 1 CDC27 PF09507.10 KFY00896.1 - 0.74 9.1 5.5 1.1 8.6 5.5 1.2 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 CDP-OH_P_transf PF01066.21 KFY00897.1 - 2.3e-14 53.9 0.9 2.3e-14 53.9 0.9 2.4 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase Tyr-DNA_phospho PF06087.12 KFY00898.1 - 1.3e-87 294.4 0.0 1.7e-87 294.1 0.0 1.1 1 0 0 1 1 1 1 Tyrosyl-DNA phosphodiesterase UIM PF02809.20 KFY00898.1 - 0.00019 21.1 2.7 0.00019 21.1 2.7 2.5 2 0 0 2 2 2 1 Ubiquitin interaction motif PLDc_2 PF13091.6 KFY00898.1 - 0.01 15.7 0.0 0.056 13.3 0.0 2.2 2 0 0 2 2 2 0 PLD-like domain Gram_pos_anchor PF00746.21 KFY00898.1 - 0.015 15.2 0.1 0.035 14.0 0.1 1.6 1 0 0 1 1 1 0 LPXTG cell wall anchor motif IPPT PF01715.17 KFY00899.1 - 3.7e-66 223.2 0.1 5.1e-66 222.8 0.1 1.1 1 0 0 1 1 1 1 IPP transferase IPT PF01745.16 KFY00899.1 - 0.00014 21.4 0.1 0.00032 20.2 0.0 1.6 2 0 0 2 2 2 1 Isopentenyl transferase zf-met PF12874.7 KFY00899.1 - 0.00018 21.8 0.1 0.00036 20.8 0.1 1.4 1 0 0 1 1 1 1 Zinc-finger of C2H2 type AAA_33 PF13671.6 KFY00899.1 - 0.0019 18.4 0.1 0.08 13.1 0.0 2.5 2 0 0 2 2 2 1 AAA domain zf-C2H2_jaz PF12171.8 KFY00899.1 - 0.015 15.6 0.0 0.027 14.8 0.0 1.4 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding ABC_tran PF00005.27 KFY00899.1 - 0.018 15.5 0.0 0.051 14.1 0.0 1.7 1 1 0 1 1 1 0 ABC transporter AAA_25 PF13481.6 KFY00899.1 - 0.022 14.3 0.0 0.055 13.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 KFY00899.1 - 0.051 14.1 0.1 0.9 10.1 0.0 2.6 2 1 0 2 2 2 0 AAA domain PhoH PF02562.16 KFY00899.1 - 0.059 12.8 0.0 0.13 11.7 0.0 1.5 2 0 0 2 2 2 0 PhoH-like protein IstB_IS21 PF01695.17 KFY00899.1 - 0.075 12.8 0.0 0.16 11.7 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein Pex2_Pex12 PF04757.14 KFY00899.1 - 0.093 12.3 0.1 0.16 11.6 0.1 1.3 1 0 0 1 1 1 0 Pex2 / Pex12 amino terminal region AKAP95 PF04988.12 KFY00899.1 - 0.11 12.8 0.0 2.5 8.3 0.0 2.4 2 0 0 2 2 2 0 A-kinase anchoring protein 95 (AKAP95) Hydin_ADK PF17213.3 KFY00899.1 - 0.14 12.5 0.2 0.53 10.5 0.0 2.0 2 0 0 2 2 2 0 Hydin Adenylate kinase-like domain SecY PF00344.20 KFY00900.1 - 1.8e-71 241.0 9.9 2.2e-71 240.6 9.9 1.1 1 0 0 1 1 1 1 SecY translocase Plug_translocon PF10559.9 KFY00900.1 - 1.9e-17 62.8 0.3 6e-17 61.2 0.3 2.0 1 0 0 1 1 1 1 Plug domain of Sec61p ABC_membrane PF00664.23 KFY00901.1 - 3.9e-55 187.4 25.0 3.2e-35 122.1 6.1 3.3 3 0 0 3 3 3 2 ABC transporter transmembrane region ABC_tran PF00005.27 KFY00901.1 - 1.1e-50 171.7 0.0 9.9e-29 100.6 0.0 2.8 2 1 0 2 2 2 2 ABC transporter SMC_N PF02463.19 KFY00901.1 - 1.5e-08 34.4 0.1 0.0021 17.6 0.0 3.9 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 KFY00901.1 - 8.8e-07 29.6 0.2 0.0015 19.1 0.1 2.7 2 0 0 2 2 2 2 AAA domain AAA_21 PF13304.6 KFY00901.1 - 4.3e-06 26.8 0.5 0.11 12.3 0.0 3.6 3 0 0 3 3 3 1 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 KFY00901.1 - 2.2e-05 24.4 0.0 0.026 14.5 0.0 2.6 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 KFY00901.1 - 2.9e-05 24.1 0.6 0.066 13.3 0.1 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_22 PF13401.6 KFY00901.1 - 0.00014 22.2 0.0 5.2 7.3 0.0 3.5 3 0 0 3 3 3 2 AAA domain AAA_29 PF13555.6 KFY00901.1 - 0.00022 20.9 0.3 0.4 10.4 0.1 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain DUF87 PF01935.17 KFY00901.1 - 0.00057 20.0 1.2 0.036 14.2 0.1 2.4 2 0 0 2 2 2 1 Helicase HerA, central domain AAA_16 PF13191.6 KFY00901.1 - 0.0013 19.2 0.0 2.1 8.7 0.0 2.8 2 0 0 2 2 2 2 AAA ATPase domain Zeta_toxin PF06414.12 KFY00901.1 - 0.0042 16.4 0.5 0.52 9.5 0.0 2.5 2 0 0 2 2 2 1 Zeta toxin T2SSE PF00437.20 KFY00901.1 - 0.006 15.7 0.2 0.055 12.5 0.1 2.1 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_25 PF13481.6 KFY00901.1 - 0.0092 15.6 0.0 0.36 10.4 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA PF00004.29 KFY00901.1 - 0.016 15.6 0.1 2.3 8.7 0.0 3.3 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 KFY00901.1 - 0.023 15.2 0.3 2 9.0 0.0 2.7 2 1 0 2 2 2 0 AAA domain IstB_IS21 PF01695.17 KFY00901.1 - 0.023 14.4 0.1 5.2 6.8 0.0 2.6 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_7 PF12775.7 KFY00901.1 - 0.038 13.5 0.1 4.5 6.8 0.0 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region ResIII PF04851.15 KFY00901.1 - 0.06 13.4 0.5 12 5.9 0.0 3.3 2 1 1 3 3 3 0 Type III restriction enzyme, res subunit DEAD PF00270.29 KFY00901.1 - 0.11 12.3 0.0 4.1 7.1 0.0 3.2 2 1 1 3 3 3 0 DEAD/DEAH box helicase AAA_5 PF07728.14 KFY00901.1 - 0.16 12.0 0.2 3.2 7.7 0.0 2.8 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) cobW PF02492.19 KFY00901.1 - 0.36 10.4 3.3 1.1 8.8 0.2 3.0 3 0 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain Mur_ligase_C PF02875.21 KFY00908.1 - 0.04 14.2 0.0 0.11 12.8 0.0 1.7 1 0 0 1 1 1 0 Mur ligase family, glutamate ligase domain Spc7_N PF15402.6 KFY00909.1 - 1.4e-224 748.4 76.8 3.5e-224 747.0 76.8 2.2 1 1 0 1 1 1 1 N-terminus of kinetochore NMS complex subunit Spc7 Spc7 PF08317.11 KFY00909.1 - 9.8e-117 389.3 5.4 9.8e-117 389.3 5.4 1.8 2 0 0 2 2 2 1 Spc7 kinetochore protein Spc7_C2 PF15577.6 KFY00909.1 - 9.9e-18 64.0 0.6 1.8e-17 63.1 0.6 1.5 1 0 0 1 1 1 1 Spc7_C2 BLOC1_2 PF10046.9 KFY00909.1 - 2.4 8.5 5.3 6.3 7.2 5.3 1.7 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Ribosomal_S17_N PF16205.5 KFY00910.1 - 2.6e-33 114.2 0.3 4.2e-33 113.5 0.3 1.4 1 0 0 1 1 1 1 Ribosomal_S17 N-terminal Ribosomal_S17 PF00366.20 KFY00910.1 - 7e-26 90.1 0.2 1.2e-25 89.3 0.2 1.4 1 0 0 1 1 1 1 Ribosomal protein S17 SecE PF00584.20 KFY00917.1 - 1e-14 54.1 0.0 1.2e-14 54.0 0.0 1.1 1 0 0 1 1 1 1 SecE/Sec61-gamma subunits of protein translocation complex WD40 PF00400.32 KFY00918.1 - 1.3e-16 60.7 16.6 0.00011 22.9 0.1 7.1 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFY00918.1 - 0.0021 18.3 0.0 0.24 11.7 0.0 3.5 4 0 0 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain Myb_DNA-binding PF00249.31 KFY00919.1 - 7.5e-22 77.3 0.5 1.6e-10 41.0 0.2 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KFY00919.1 - 2.1e-14 53.5 0.1 3.4e-06 27.2 0.0 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain SLIDE PF09111.10 KFY00919.1 - 1.4e-07 31.6 0.1 0.0012 18.8 0.0 2.5 2 0 0 2 2 2 2 SLIDE Semialdhyde_dhC PF02774.18 KFY00920.1 - 3.1e-39 135.0 0.0 4.1e-39 134.5 0.0 1.2 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, dimerisation domain Semialdhyde_dh PF01118.24 KFY00920.1 - 1.1e-29 103.3 0.0 8.5e-29 100.4 0.0 2.2 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain DapB_N PF01113.20 KFY00920.1 - 0.0038 17.4 0.0 0.0086 16.2 0.0 1.6 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus Sacchrp_dh_NADP PF03435.18 KFY00920.1 - 0.0067 16.7 0.0 0.027 14.7 0.0 1.9 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain DXP_reductoisom PF02670.16 KFY00920.1 - 0.034 14.8 0.0 0.086 13.6 0.0 1.8 1 0 0 1 1 1 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase SAICAR_synt PF01259.18 KFY00921.1 - 4.4e-99 331.2 0.0 5e-99 331.0 0.0 1.0 1 0 0 1 1 1 1 SAICAR synthetase Ribosomal_S4e PF00900.20 KFY00922.1 - 1e-36 124.7 0.1 2.4e-36 123.5 0.1 1.7 1 0 0 1 1 1 1 Ribosomal family S4e 40S_S4_C PF16121.5 KFY00922.1 - 3.1e-24 84.3 0.1 5.3e-24 83.6 0.1 1.4 1 0 0 1 1 1 1 40S ribosomal protein S4 C-terminus RS4NT PF08071.12 KFY00922.1 - 1.5e-18 66.6 6.9 2.8e-18 65.7 6.9 1.4 1 0 0 1 1 1 1 RS4NT (NUC023) domain S4 PF01479.25 KFY00922.1 - 2e-07 30.6 0.0 4.4e-07 29.5 0.0 1.6 1 0 0 1 1 1 1 S4 domain KOW PF00467.29 KFY00922.1 - 0.00091 19.1 0.7 0.00091 19.1 0.7 2.9 3 0 0 3 3 3 1 KOW motif FAD-oxidase_C PF02913.19 KFY00923.1 - 2.4e-62 210.8 0.1 3.4e-62 210.3 0.1 1.2 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 KFY00923.1 - 7.2e-33 113.3 0.0 1.4e-32 112.4 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain ANF_receptor PF01094.28 KFY00923.1 - 0.054 12.6 0.0 0.085 11.9 0.0 1.2 1 0 0 1 1 1 0 Receptor family ligand binding region SepSecS PF05889.13 KFY00923.1 - 0.077 11.7 0.0 0.15 10.7 0.0 1.4 1 0 0 1 1 1 0 O-phosphoseryl-tRNA(Sec) selenium transferase, SepSecS BaffR-Tall_bind PF09256.10 KFY00923.1 - 0.23 11.2 0.4 0.43 10.4 0.4 1.4 1 0 0 1 1 1 0 BAFF-R, TALL-1 binding RdRP PF05183.12 KFY00924.1 - 6.2e-194 645.9 0.0 8.8e-194 645.4 0.0 1.2 1 0 0 1 1 1 1 RNA dependent RNA polymerase RRM_1 PF00076.22 KFY00924.1 - 0.09 12.6 0.0 0.23 11.3 0.0 1.7 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CAP_N PF01213.19 KFY00927.1 - 2.3 7.6 6.0 4 6.8 6.0 1.4 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Peptidase_S8 PF00082.22 KFY00929.1 - 8e-35 120.5 14.9 1.4e-34 119.7 14.9 1.3 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.16 KFY00929.1 - 1.4e-06 28.8 2.2 1.4e-06 28.8 0.7 1.8 2 0 0 2 2 2 1 Peptidase inhibitor I9 Arginase PF00491.21 KFY00930.1 - 2.3e-25 89.6 0.0 2.8e-25 89.4 0.0 1.0 1 0 0 1 1 1 1 Arginase family BTB PF00651.31 KFY00931.1 - 8.3e-14 51.8 0.0 1.3e-13 51.2 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain HypA PF01155.19 KFY00931.1 - 0.024 14.6 0.2 0.047 13.7 0.2 1.5 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Rubredoxin_2 PF18073.1 KFY00931.1 - 0.11 12.2 1.3 1.3 8.8 0.0 2.3 2 0 0 2 2 2 0 Rubredoxin metal binding domain DNA_RNApol_7kD PF03604.13 KFY00931.1 - 0.55 10.0 4.6 7.5 6.3 0.6 2.5 2 0 0 2 2 2 0 DNA directed RNA polymerase, 7 kDa subunit MOSC PF03473.17 KFY00934.1 - 9.9e-28 96.8 0.0 1.4e-27 96.3 0.0 1.2 1 0 0 1 1 1 1 MOSC domain MOSC_N PF03476.16 KFY00934.1 - 3.1e-12 46.4 0.0 6.7e-12 45.3 0.0 1.6 1 0 0 1 1 1 1 MOSC N-terminal beta barrel domain Mito_carr PF00153.27 KFY00936.1 - 1.4e-53 178.8 1.4 2.1e-18 66.0 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein vWA-TerF-like PF10138.9 KFY00951.1 - 7.2e-07 29.5 0.0 1.1e-06 28.9 0.0 1.2 1 0 0 1 1 1 1 vWA found in TerF C terminus ABC2_membrane PF01061.24 KFY00952.1 - 2.3e-79 265.7 48.3 4.2e-47 160.3 20.9 3.1 4 0 0 4 4 4 2 ABC-2 type transporter ABC_tran PF00005.27 KFY00952.1 - 2.6e-40 138.1 0.0 6e-19 68.9 0.0 2.9 3 0 0 3 3 2 2 ABC transporter PDR_CDR PF06422.12 KFY00952.1 - 1.3e-22 79.5 8.5 1.8e-22 79.1 0.1 3.3 3 0 0 3 3 2 1 CDR ABC transporter Fungal_trans PF04082.18 KFY00952.1 - 5.7e-12 45.2 0.1 1.2e-11 44.2 0.1 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KFY00952.1 - 7.8e-09 35.5 10.5 1.5e-08 34.6 10.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ABC2_membrane_3 PF12698.7 KFY00952.1 - 6.7e-07 28.7 40.4 1.1e-06 28.0 14.7 2.9 3 0 0 3 3 3 2 ABC-2 family transporter protein AAA_16 PF13191.6 KFY00952.1 - 2e-05 25.1 0.1 0.05 14.0 0.0 2.8 2 0 0 2 2 2 2 AAA ATPase domain ABC_trans_N PF14510.6 KFY00952.1 - 2.2e-05 25.0 0.3 6.2e-05 23.5 0.3 1.8 1 0 0 1 1 1 1 ABC-transporter N-terminal AAA_22 PF13401.6 KFY00952.1 - 4.6e-05 23.7 0.7 1.7 8.9 0.2 4.1 3 1 0 3 3 3 2 AAA domain AAA_25 PF13481.6 KFY00952.1 - 0.0013 18.3 0.2 0.028 14.0 0.1 2.3 2 0 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 KFY00952.1 - 0.0018 18.2 0.2 0.0098 15.8 0.0 2.1 2 0 0 2 2 2 1 RsgA GTPase AAA_29 PF13555.6 KFY00952.1 - 0.0019 17.9 0.6 0.14 11.9 0.1 2.7 2 0 0 2 2 2 1 P-loop containing region of AAA domain cobW PF02492.19 KFY00952.1 - 0.0086 15.7 0.7 2.6 7.6 0.4 2.5 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_28 PF13521.6 KFY00952.1 - 0.0093 16.2 0.7 1.4 9.1 0.2 2.6 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 KFY00952.1 - 0.013 15.7 0.0 1.8 8.7 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 KFY00952.1 - 0.017 15.7 0.0 9.2 6.8 0.0 3.1 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 KFY00952.1 - 0.031 14.2 0.2 4.6 7.1 0.1 2.5 2 0 0 2 2 2 0 NACHT domain AAA PF00004.29 KFY00952.1 - 0.14 12.6 0.0 17 5.9 0.0 2.7 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 KFY00952.1 - 0.14 11.8 0.6 10 5.8 0.3 2.3 2 0 0 2 2 2 0 AAA domain DnaB_C PF03796.15 KFY00952.1 - 0.16 11.3 0.0 0.91 8.8 0.0 2.2 2 0 0 2 2 2 0 DnaB-like helicase C terminal domain PduV-EutP PF10662.9 KFY00952.1 - 0.24 11.2 0.7 14 5.4 0.2 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation TPR_2 PF07719.17 KFY00954.1 - 2.2e-09 36.7 10.1 0.014 15.5 0.0 5.3 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_1 PF00515.28 KFY00954.1 - 1.5e-05 24.6 4.3 0.34 10.8 0.0 5.2 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_11 PF13414.6 KFY00954.1 - 0.0019 17.8 8.7 3.4 7.4 0.1 5.4 5 0 0 5 5 5 1 TPR repeat TPR_4 PF07721.14 KFY00954.1 - 0.0078 16.7 5.9 0.47 11.2 2.2 3.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.6 KFY00954.1 - 0.029 15.2 15.2 3.6 8.7 0.3 6.4 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_12 PF13424.6 KFY00954.1 - 0.058 13.7 7.1 2.6 8.4 2.7 3.7 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_19 PF14559.6 KFY00954.1 - 0.059 13.9 11.4 0.97 10.0 0.3 5.5 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_7 PF13176.6 KFY00954.1 - 0.16 12.1 0.5 3.7 7.8 0.2 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.6 KFY00954.1 - 0.25 12.0 18.4 1.6 9.4 0.2 5.8 6 1 1 7 7 7 0 Tetratricopeptide repeat TPR_8 PF13181.6 KFY00954.1 - 0.47 10.8 5.0 13 6.3 0.3 4.4 6 0 0 6 6 6 0 Tetratricopeptide repeat Epimerase PF01370.21 KFY00955.1 - 1.2e-13 51.1 0.1 8.8e-13 48.3 0.1 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 KFY00955.1 - 2.4e-05 24.3 0.1 6.3e-05 22.9 0.1 1.8 1 1 0 1 1 1 1 NAD(P)H-binding Sacchrp_dh_NADP PF03435.18 KFY00955.1 - 6.4e-05 23.2 0.0 0.00011 22.4 0.0 1.5 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain NmrA PF05368.13 KFY00955.1 - 0.00013 21.7 0.1 0.0002 21.0 0.1 1.3 1 0 0 1 1 1 1 NmrA-like family RmlD_sub_bind PF04321.17 KFY00955.1 - 0.024 13.7 0.0 0.49 9.4 0.0 2.3 2 0 0 2 2 2 0 RmlD substrate binding domain NAD_binding_4 PF07993.12 KFY00955.1 - 0.12 11.6 0.2 1.9 7.6 0.0 2.2 1 1 1 2 2 2 0 Male sterility protein ABM PF03992.16 KFY00956.1 - 0.00046 20.2 0.1 0.0006 19.9 0.1 1.3 1 1 0 1 1 1 1 Antibiotic biosynthesis monooxygenase Fungal_trans_2 PF11951.8 KFY00957.1 - 3.2e-16 59.1 0.1 4e-16 58.8 0.1 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Fungal_trans_2 PF11951.8 KFY00958.1 - 5.6e-10 38.6 1.6 7.2e-10 38.2 1.6 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KFY00958.1 - 3.2e-05 23.9 8.1 5.1e-05 23.3 8.1 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Gly_transf_sug PF04488.15 KFY00960.1 - 1.3e-08 35.4 0.0 3.1e-08 34.2 0.0 1.6 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif TcdA_TcdB PF12919.7 KFY00960.1 - 0.02 14.2 0.1 0.031 13.6 0.1 1.2 1 0 0 1 1 1 0 TcdA/TcdB catalytic glycosyltransferase domain Stn1 PF10451.9 KFY00961.1 - 0.0027 16.7 0.0 0.0031 16.5 0.0 1.1 1 0 0 1 1 1 1 Telomere regulation protein Stn1 Ribosomal_S7 PF00177.21 KFY00962.1 - 3.6e-27 94.8 0.0 5.7e-27 94.2 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e DND1_DSRM PF14709.7 KFY00963.1 - 0.0076 16.5 0.2 0.077 13.3 0.2 2.1 1 1 0 1 1 1 1 double strand RNA binding domain from DEAD END PROTEIN 1 dsrm PF00035.26 KFY00963.1 - 0.019 15.7 0.1 0.039 14.7 0.1 1.5 1 1 0 1 1 1 0 Double-stranded RNA binding motif RPA_interact_N PF14766.6 KFY00963.1 - 0.075 12.7 0.0 0.11 12.1 0.0 1.3 1 0 0 1 1 1 0 Replication protein A interacting N-terminal DUF2183 PF09949.9 KFY00966.1 - 7e-31 106.5 0.0 1.8e-30 105.2 0.0 1.8 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2183) AMP-binding PF00501.28 KFY00966.1 - 5.9e-12 44.9 0.1 2.4e-11 42.9 0.1 1.8 1 1 0 1 1 1 1 AMP-binding enzyme CarboxypepD_reg PF13620.6 KFY00966.1 - 0.085 13.1 0.3 0.58 10.5 0.1 2.3 2 0 0 2 2 2 0 Carboxypeptidase regulatory-like domain DEAD PF00270.29 KFY00967.1 - 8.6e-47 159.2 0.0 1.9e-46 158.0 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KFY00967.1 - 4.5e-30 104.2 0.1 9.3e-29 100.0 0.0 2.6 3 0 0 3 3 3 1 Helicase conserved C-terminal domain UTP25 PF06862.12 KFY00967.1 - 0.021 13.6 0.8 0.19 10.4 0.1 2.7 1 1 2 3 3 3 0 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 Acetyltransf_1 PF00583.25 KFY00968.1 - 0.0041 17.3 0.0 0.0088 16.3 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KFY00968.1 - 0.069 13.6 0.0 0.13 12.7 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KFY00968.1 - 0.23 11.4 0.0 0.67 9.9 0.1 1.7 1 1 1 2 2 2 0 Acetyltransferase (GNAT) domain Arf PF00025.21 KFY00969.1 - 3.2e-68 228.6 0.4 3.5e-68 228.5 0.4 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.22 KFY00969.1 - 9e-14 51.4 0.0 1e-13 51.2 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFY00969.1 - 2.5e-12 47.1 0.0 3.5e-12 46.6 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase G-alpha PF00503.20 KFY00969.1 - 3.3e-12 46.3 0.8 8.6e-07 28.4 0.1 2.3 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.12 KFY00969.1 - 7.1e-10 38.6 0.0 8.3e-10 38.4 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 KFY00969.1 - 1e-07 32.0 0.0 1.6e-07 31.4 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 KFY00969.1 - 3.8e-07 29.7 0.0 4.7e-07 29.4 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.27 KFY00969.1 - 0.00041 20.0 0.0 0.0081 15.7 0.0 2.2 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain FeoB_N PF02421.18 KFY00969.1 - 0.029 13.9 0.2 0.084 12.4 0.2 1.8 1 1 0 1 1 1 0 Ferrous iron transport protein B NACHT PF05729.12 KFY00969.1 - 0.045 13.7 0.0 0.64 9.9 0.0 2.0 2 0 0 2 2 2 0 NACHT domain Dynamin_N PF00350.23 KFY00969.1 - 0.13 12.3 0.0 0.97 9.5 0.0 2.0 2 0 0 2 2 2 0 Dynamin family PduV-EutP PF10662.9 KFY00969.1 - 0.16 11.7 0.1 0.37 10.5 0.1 1.6 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation 6PF2K PF01591.18 KFY00969.1 - 0.17 11.2 0.1 0.32 10.3 0.0 1.5 2 0 0 2 2 2 0 6-phosphofructo-2-kinase DUF4045 PF13254.6 KFY00970.1 - 1.4e-99 334.6 47.5 7.6e-64 216.9 30.7 5.1 3 2 3 6 6 6 2 Domain of unknown function (DUF4045) PDEase_II PF02112.15 KFY00971.1 - 1e-52 179.4 0.0 3.2e-44 151.4 0.0 3.0 2 1 0 2 2 2 2 cAMP phosphodiesterases class-II Lactamase_B PF00753.27 KFY00971.1 - 0.014 15.4 0.1 0.029 14.4 0.1 1.7 1 0 0 1 1 1 0 Metallo-beta-lactamase superfamily Chlorosome_CsmC PF11098.8 KFY00975.1 - 0.081 12.9 8.6 0.13 12.3 8.6 1.5 1 1 0 1 1 1 0 Chlorosome envelope protein C DUF3614 PF12267.8 KFY00976.1 - 7.5 7.0 7.0 0.99 9.9 1.3 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3614) MDM10 PF12519.8 KFY00977.1 - 0.64 8.8 2.1 0.72 8.7 2.1 1.0 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 Endostatin PF06482.11 KFY00977.1 - 0.81 9.1 5.5 1 8.8 5.5 1.1 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin eIF-3_zeta PF05091.12 KFY00977.1 - 1 8.2 6.0 1.2 8.0 6.0 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Pex14_N PF04695.13 KFY00977.1 - 4 8.1 12.5 4.5 7.9 12.5 1.2 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Lin-8 PF03353.15 KFY00977.1 - 7.8 6.0 10.7 8.5 5.8 10.7 1.0 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist MacB_PCD PF12704.7 KFY00979.1 - 0.061 13.7 0.0 0.074 13.4 0.0 1.2 1 0 0 1 1 1 0 MacB-like periplasmic core domain Tsg PF04668.12 KFY00980.1 - 0.13 12.9 0.3 0.16 12.7 0.3 1.1 1 0 0 1 1 1 0 Twisted gastrulation (Tsg) protein conserved region Pes-10 PF07149.11 KFY00981.1 - 9.3 5.2 7.8 16 4.4 7.8 1.3 1 0 0 1 1 1 0 Pes-10 DUF3659 PF12396.8 KFY00982.1 - 6.1e-112 365.6 68.2 7.7e-23 80.2 7.6 6.4 6 0 0 6 6 6 6 Protein of unknown function (DUF3659) PMC2NT PF08066.12 KFY00982.1 - 0.06 14.0 0.2 0.97 10.2 0.1 2.7 2 0 0 2 2 2 0 PMC2NT (NUC016) domain CorA PF01544.18 KFY00982.1 - 0.3 10.4 0.3 0.49 9.7 0.3 1.3 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein DUF1993 PF09351.10 KFY00982.1 - 0.67 10.1 3.4 0.25 11.5 0.8 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF1993) 2H-phosphodiest PF08975.10 KFY00983.1 - 5.6e-13 48.9 0.0 1.6e-11 44.2 0.0 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF1868) LigT_PEase PF02834.16 KFY00983.1 - 8.6e-05 22.7 0.0 0.00021 21.4 0.0 1.7 1 0 0 1 1 1 1 LigT like Phosphoesterase 2_5_RNA_ligase2 PF13563.6 KFY00983.1 - 0.00016 21.6 0.7 0.00039 20.4 0.2 1.9 1 1 1 2 2 2 1 2'-5' RNA ligase superfamily HVSL PF09749.9 KFY00983.1 - 0.13 11.7 0.0 0.72 9.3 0.0 1.9 2 0 0 2 2 2 0 Uncharacterised conserved protein Catalase PF00199.19 KFY00985.1 - 5.7e-193 641.2 1.9 7.3e-193 640.9 1.9 1.1 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.12 KFY00985.1 - 1.9e-10 40.8 0.0 5.5e-10 39.3 0.0 1.8 1 0 0 1 1 1 1 Catalase-related immune-responsive ECH_1 PF00378.20 KFY00986.1 - 2.3e-31 109.0 0.1 2.6e-31 108.9 0.1 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KFY00986.1 - 1.9e-07 30.9 0.2 0.00024 20.7 0.1 2.0 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase Transferase PF02458.15 KFY00987.1 - 2.6e-30 105.5 0.0 5.1e-30 104.5 0.0 1.4 1 1 0 1 1 1 1 Transferase family Condensation PF00668.20 KFY00987.1 - 0.014 14.1 0.0 0.02 13.6 0.0 1.2 1 0 0 1 1 1 0 Condensation domain Kinesin PF00225.23 KFY00990.1 - 1.4e-33 116.2 0.0 2.3e-33 115.6 0.0 1.3 1 0 0 1 1 1 1 Kinesin motor domain Trimer_CC PF08954.11 KFY00990.1 - 0.57 9.8 9.4 0.41 10.3 1.2 3.0 2 0 0 2 2 2 0 Trimerisation motif DivIC PF04977.15 KFY00990.1 - 1.7 8.5 4.3 30 4.5 1.9 2.7 3 0 0 3 3 3 0 Septum formation initiator ADIP PF11559.8 KFY00990.1 - 2.1 8.4 5.2 1.4 9.0 2.3 2.1 1 1 0 1 1 1 0 Afadin- and alpha -actinin-Binding bZIP_2 PF07716.15 KFY00990.1 - 2.2 8.4 10.1 2.4 8.3 2.3 2.8 2 0 0 2 2 2 0 Basic region leucine zipper Fungal_trans PF04082.18 KFY00994.1 - 8.4e-09 34.8 0.2 1.3e-08 34.2 0.2 1.5 1 1 0 1 1 1 1 Fungal specific transcription factor domain Glyco_hydro_31 PF01055.26 KFY00995.1 - 5e-88 296.2 3.6 6.5e-88 295.8 3.6 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 DUF4968 PF16338.5 KFY00995.1 - 5.6e-08 33.0 0.0 1.5e-07 31.7 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4968) Sugar_tr PF00083.24 KFY00996.1 - 9.5e-85 285.1 23.0 1.2e-84 284.8 23.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KFY00996.1 - 2.1e-15 56.5 28.9 2.1e-15 56.5 28.9 1.8 2 0 0 2 2 2 1 Major Facilitator Superfamily MFS_2 PF13347.6 KFY00996.1 - 3.9e-06 25.7 23.6 0.0011 17.6 4.0 2.8 3 0 0 3 3 3 2 MFS/sugar transport protein Romo1 PF10247.9 KFY00996.1 - 0.023 15.1 1.6 0.09 13.2 1.6 2.0 1 0 0 1 1 1 0 Reactive mitochondrial oxygen species modulator 1 MFS_1_like PF12832.7 KFY00996.1 - 0.26 10.1 11.6 0.093 11.6 5.6 2.3 2 0 0 2 2 2 0 MFS_1 like family Fungal_trans PF04082.18 KFY00997.1 - 7.1e-15 54.8 1.2 1.2e-14 54.0 1.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KFY00997.1 - 3.3e-08 33.5 12.5 5.4e-08 32.8 12.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain NmrA PF05368.13 KFY00998.1 - 1.4e-36 126.2 0.0 1.9e-36 125.8 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KFY00998.1 - 5.5e-20 72.0 0.0 6.3e-20 71.8 0.0 1.1 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KFY00998.1 - 0.00054 19.5 0.0 0.0014 18.1 0.0 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.10 KFY00998.1 - 0.01 15.8 0.0 0.019 14.9 0.0 1.5 1 1 0 1 1 1 0 KR domain NAD_binding_4 PF07993.12 KFY00998.1 - 0.014 14.5 0.0 0.031 13.4 0.0 1.6 2 0 0 2 2 2 0 Male sterility protein 3Beta_HSD PF01073.19 KFY00998.1 - 0.014 14.4 0.0 0.026 13.5 0.0 1.5 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 KFY00998.1 - 0.096 12.1 0.0 0.14 11.5 0.0 1.2 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase DapB_N PF01113.20 KFY00998.1 - 0.12 12.4 0.0 0.29 11.3 0.0 1.6 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus CDH PF02611.15 KFY00999.1 - 0.02 14.5 0.1 0.032 13.9 0.1 1.2 1 0 0 1 1 1 0 CDP-diacylglycerol pyrophosphatase Meth_synt_2 PF01717.18 KFY00999.1 - 0.027 13.8 0.0 0.047 13.0 0.0 1.3 1 0 0 1 1 1 0 Cobalamin-independent synthase, Catalytic domain NACHT PF05729.12 KFY01000.1 - 2.9e-09 37.1 0.0 5.7e-09 36.1 0.0 1.5 1 0 0 1 1 1 1 NACHT domain DUF676 PF05057.14 KFY01000.1 - 0.00031 20.3 0.0 0.00056 19.5 0.0 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) PGAP1 PF07819.13 KFY01000.1 - 0.0012 18.6 0.0 0.0047 16.7 0.0 1.9 2 0 0 2 2 2 1 PGAP1-like protein AAA_16 PF13191.6 KFY01000.1 - 0.0015 19.0 0.1 0.0075 16.7 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain Abhydrolase_6 PF12697.7 KFY01000.1 - 0.0016 19.1 1.3 0.005 17.5 1.3 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Cutinase PF01083.22 KFY01000.1 - 0.038 13.9 0.0 0.079 12.9 0.0 1.5 1 0 0 1 1 1 0 Cutinase AAA_22 PF13401.6 KFY01000.1 - 0.12 12.6 0.0 0.34 11.2 0.0 1.8 1 0 0 1 1 1 0 AAA domain Epimerase PF01370.21 KFY01001.1 - 6.7e-17 61.8 0.0 1.4e-16 60.7 0.0 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KFY01001.1 - 7.2e-06 25.6 0.0 1.8e-05 24.4 0.0 1.6 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.12 KFY01001.1 - 0.00088 18.5 0.0 0.039 13.1 0.0 2.2 2 0 0 2 2 2 1 Male sterility protein NAD_binding_10 PF13460.6 KFY01001.1 - 0.0028 17.6 0.0 0.0083 16.0 0.0 1.9 2 0 0 2 2 2 1 NAD(P)H-binding 2-oxoacid_dh PF00198.23 KFY01001.1 - 0.005 16.3 0.0 0.0079 15.7 0.0 1.2 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) 3Beta_HSD PF01073.19 KFY01001.1 - 0.016 14.3 0.0 0.03 13.3 0.0 1.5 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 KFY01001.1 - 0.1 11.7 0.0 0.26 10.3 0.0 1.6 2 0 0 2 2 2 0 RmlD substrate binding domain NmrA PF05368.13 KFY01001.1 - 0.15 11.6 0.1 15 5.1 0.0 2.2 2 0 0 2 2 2 0 NmrA-like family Zn_clus PF00172.18 KFY01002.1 - 1.2e-05 25.4 10.5 1.2e-05 25.4 10.5 1.9 3 0 0 3 3 3 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KFY01002.1 - 1.8e-05 24.0 2.5 8e-05 21.8 0.0 2.7 3 0 0 3 3 3 1 Fungal specific transcription factor domain DLH PF01738.18 KFY01003.1 - 2.9e-07 30.3 1.2 1.5e-06 28.0 0.5 2.3 2 1 0 2 2 2 1 Dienelactone hydrolase family Abhydrolase_6 PF12697.7 KFY01003.1 - 1.2e-05 26.0 0.1 2.2e-05 25.2 0.1 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KFY01003.1 - 0.00012 21.4 0.0 0.00017 21.0 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KFY01003.1 - 0.0044 16.7 0.0 0.0052 16.5 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold BAAT_C PF08840.11 KFY01003.1 - 0.0081 16.1 0.0 0.013 15.4 0.0 1.4 1 0 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal CbiA PF01656.23 KFY01003.1 - 0.13 12.3 0.0 0.16 12.0 0.0 1.3 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain Hydrolase_4 PF12146.8 KFY01004.1 - 0.12 11.6 0.0 0.15 11.3 0.0 1.2 1 0 0 1 1 1 0 Serine aminopeptidase, S33 HAD_SAK_1 PF10307.9 KFY01005.1 - 5.4e-78 261.4 0.0 8e-78 260.9 0.0 1.3 1 0 0 1 1 1 1 HAD domain family 1 in Swiss Army Knife RNA repair proteins DNA_primase_S PF01896.19 KFY01006.1 - 5.8e-65 218.6 0.2 8.1e-65 218.2 0.2 1.2 1 0 0 1 1 1 1 DNA primase small subunit BTB PF00651.31 KFY01007.1 - 1.6e-09 38.0 0.0 2.8e-09 37.2 0.0 1.2 1 0 0 1 1 1 1 BTB/POZ domain Phage_connect_1 PF05135.13 KFY01007.1 - 0.14 12.7 0.0 0.33 11.5 0.0 1.6 1 0 0 1 1 1 0 Phage gp6-like head-tail connector protein F-box-like PF12937.7 KFY01012.1 - 8.9e-07 28.7 0.0 2.8e-06 27.1 0.0 1.9 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KFY01012.1 - 7.2e-05 22.6 0.0 0.00027 20.7 0.0 2.0 1 0 0 1 1 1 1 F-box domain Syntaxin PF00804.25 KFY01013.1 - 6.1e-20 71.7 10.1 2.2e-19 69.9 10.1 1.8 1 1 0 1 1 1 1 Syntaxin SNARE PF05739.19 KFY01013.1 - 7.7e-09 35.4 1.4 2.9e-08 33.6 1.4 2.1 1 0 0 1 1 1 1 SNARE domain Syntaxin_2 PF14523.6 KFY01013.1 - 0.002 18.5 6.9 0.015 15.7 0.7 2.3 2 0 0 2 2 2 1 Syntaxin-like protein T2SSF PF00482.23 KFY01013.1 - 0.0072 16.3 2.6 0.036 14.0 2.5 2.2 1 1 0 1 1 1 1 Type II secretion system (T2SS), protein F PTA_PTB PF01515.19 KFY01013.1 - 0.01 15.2 2.3 0.016 14.6 2.3 1.2 1 0 0 1 1 1 0 Phosphate acetyl/butaryl transferase Vac_Fusion PF02346.16 KFY01013.1 - 0.016 14.9 5.6 0.097 12.3 0.2 2.8 3 0 0 3 3 3 0 Chordopoxvirus multifunctional envelope protein A27 V-SNARE PF05008.15 KFY01013.1 - 0.017 15.5 1.4 0.017 15.5 1.4 3.0 2 2 1 3 3 3 0 Vesicle transport v-SNARE protein N-terminus DUF2207 PF09972.9 KFY01013.1 - 0.019 13.8 0.1 0.03 13.1 0.1 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF2534 PF10749.9 KFY01013.1 - 0.024 14.8 0.3 0.041 14.1 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2534) DUF4094 PF13334.6 KFY01013.1 - 0.039 14.4 0.6 0.039 14.4 0.6 2.9 2 2 2 4 4 4 0 Domain of unknown function (DUF4094) Claudin_3 PF06653.11 KFY01013.1 - 0.05 13.5 0.6 0.08 12.9 0.6 1.2 1 0 0 1 1 1 0 Tight junction protein, Claudin-like MCPsignal PF00015.21 KFY01013.1 - 0.061 13.1 6.9 0.06 13.2 5.0 1.8 2 0 0 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain Allexi_40kDa PF05549.11 KFY01013.1 - 0.067 12.7 5.0 0.16 11.5 0.2 2.2 2 0 0 2 2 2 0 Allexivirus 40kDa protein SP_C-Propep PF08999.10 KFY01013.1 - 0.1 12.4 4.6 0.21 11.4 4.6 1.4 1 0 0 1 1 1 0 Surfactant protein C, N terminal propeptide DUF3328 PF11807.8 KFY01013.1 - 0.16 11.7 0.0 0.35 10.6 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3328) AI-2E_transport PF01594.16 KFY01013.1 - 0.19 10.8 3.1 0.26 10.4 1.0 1.9 1 1 1 2 2 2 0 AI-2E family transporter HHH_2 PF12826.7 KFY01013.1 - 0.22 11.6 2.7 0.21 11.7 0.4 2.0 2 0 0 2 2 2 0 Helix-hairpin-helix motif SKA1 PF07160.12 KFY01013.1 - 1.3 8.9 9.2 0.13 12.1 1.4 2.5 2 1 1 3 3 3 0 Spindle and kinetochore-associated protein 1 Spectrin PF00435.21 KFY01013.1 - 3.1 8.3 8.5 5.4 7.6 1.6 2.7 2 1 0 2 2 2 0 Spectrin repeat SlyX PF04102.12 KFY01013.1 - 7.2 7.3 7.3 3.8 8.2 1.2 3.1 3 0 0 3 3 3 0 SlyX Methyltransf_23 PF13489.6 KFY01024.1 - 1.5e-12 47.6 0.0 2.3e-12 47.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KFY01024.1 - 1.3e-07 32.1 0.0 6.8e-07 29.9 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KFY01024.1 - 2.7e-07 30.5 0.0 8.3e-07 28.9 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KFY01024.1 - 1.3e-06 29.0 0.0 4.1e-06 27.5 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KFY01024.1 - 4.1e-05 24.2 0.0 0.00041 21.0 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_9 PF08003.11 KFY01024.1 - 0.027 13.4 0.0 0.12 11.3 0.0 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1698) Ubie_methyltran PF01209.18 KFY01024.1 - 0.051 12.9 0.0 1 8.7 0.0 2.2 2 1 0 2 2 2 0 ubiE/COQ5 methyltransferase family SH2_2 PF14633.6 KFY01024.1 - 0.15 11.4 0.0 0.24 10.8 0.0 1.2 1 0 0 1 1 1 0 SH2 domain FAD_binding_3 PF01494.19 KFY01026.1 - 1.6e-13 50.6 0.0 6.9e-08 32.1 0.0 3.1 3 0 0 3 3 3 3 FAD binding domain NAD_binding_8 PF13450.6 KFY01026.1 - 0.00039 20.6 0.1 0.00096 19.3 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KFY01026.1 - 0.0074 15.6 0.1 0.015 14.6 0.1 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KFY01026.1 - 0.012 14.7 0.3 0.046 12.8 0.1 2.0 3 0 0 3 3 3 0 FAD binding domain Pyr_redox_3 PF13738.6 KFY01026.1 - 0.013 14.8 0.0 0.024 13.9 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.16 KFY01026.1 - 0.017 14.8 0.1 0.033 13.9 0.1 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA DAO PF01266.24 KFY01026.1 - 0.03 13.9 0.1 0.057 13.0 0.1 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase TrkA_N PF02254.18 KFY01026.1 - 0.034 14.4 0.2 1 9.6 0.0 2.5 2 0 0 2 2 2 0 TrkA-N domain Lycopene_cycl PF05834.12 KFY01026.1 - 0.058 12.4 0.4 0.23 10.4 0.1 2.0 3 0 0 3 3 3 0 Lycopene cyclase protein Thi4 PF01946.17 KFY01026.1 - 0.13 11.5 0.0 0.22 10.7 0.0 1.4 1 0 0 1 1 1 0 Thi4 family FSH1 PF03959.13 KFY01028.1 - 1.2e-55 188.4 0.0 1.6e-55 188.1 0.0 1.1 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Esterase_phd PF10503.9 KFY01028.1 - 0.0027 17.2 0.8 1.2 8.5 0.6 2.2 2 0 0 2 2 2 2 Esterase PHB depolymerase Abhydrolase_2 PF02230.16 KFY01028.1 - 0.097 12.5 0.1 9.6 5.9 0.1 2.9 2 1 1 3 3 3 0 Phospholipase/Carboxylesterase AXE1 PF05448.12 KFY01028.1 - 0.23 10.1 0.8 1.4 7.5 0.2 2.1 2 0 0 2 2 2 0 Acetyl xylan esterase (AXE1) RPE65 PF03055.15 KFY01029.1 - 9e-84 282.3 0.0 1.4e-83 281.7 0.0 1.2 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein DUF3433 PF11915.8 KFY01029.1 - 1.6e-21 76.5 30.7 2.5e-12 47.1 5.3 4.0 5 0 0 5 5 5 2 Protein of unknown function (DUF3433) PCI PF01399.27 KFY01029.1 - 6.8e-20 71.5 0.3 2e-19 70.1 0.1 1.9 2 0 0 2 2 2 1 PCI domain RPN5_C PF18098.1 KFY01029.1 - 1.9e-15 56.7 2.1 4.2e-15 55.5 1.1 2.1 2 0 0 2 2 2 1 26S proteasome regulatory subunit RPN5 C-terminal domain LMF1 PF06762.14 KFY01029.1 - 0.0086 15.2 1.2 0.022 13.9 1.2 1.6 1 0 0 1 1 1 1 Lipase maturation factor Mo-co_dimer PF03404.16 KFY01030.1 - 1.2e-59 200.2 0.1 2.4e-59 199.3 0.1 1.5 1 0 0 1 1 1 1 Mo-co oxidoreductase dimerisation domain Oxidored_molyb PF00174.19 KFY01030.1 - 1.3e-46 158.4 0.0 2.6e-46 157.4 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain FAD_binding_6 PF00970.24 KFY01030.1 - 9.9e-33 112.5 0.0 1.6e-32 111.8 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.21 KFY01030.1 - 3.5e-29 101.7 0.0 8.8e-29 100.4 0.0 1.7 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Cyt-b5 PF00173.28 KFY01030.1 - 1.5e-18 66.7 0.0 3.3e-18 65.6 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain NAD_binding_6 PF08030.12 KFY01030.1 - 0.001 19.2 0.1 0.17 12.0 0.0 2.4 1 1 0 2 2 2 2 Ferric reductase NAD binding domain Pyr_redox_2 PF07992.14 KFY01031.1 - 2.4e-46 158.3 0.0 3.6e-46 157.7 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NIR_SIR PF01077.22 KFY01031.1 - 6.1e-21 74.6 0.0 1.4e-20 73.4 0.0 1.6 1 0 0 1 1 1 1 Nitrite and sulphite reductase 4Fe-4S domain Pyr_redox PF00070.27 KFY01031.1 - 1.9e-16 60.4 1.1 1.8e-14 54.0 0.1 3.3 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Rieske_2 PF13806.6 KFY01031.1 - 2.8e-14 52.9 0.0 5.9e-14 51.9 0.0 1.6 1 0 0 1 1 1 1 Rieske-like [2Fe-2S] domain Fer2_BFD PF04324.15 KFY01031.1 - 5.8e-14 52.2 6.7 1.1e-11 44.9 6.1 2.7 2 0 0 2 2 2 1 BFD-like [2Fe-2S] binding domain Rieske PF00355.26 KFY01031.1 - 1.8e-10 40.6 0.4 6.8e-10 38.8 0.0 2.2 2 0 0 2 2 2 1 Rieske [2Fe-2S] domain NIR_SIR_ferr PF03460.17 KFY01031.1 - 3.8e-09 36.3 0.0 2e-08 33.9 0.0 2.2 2 0 0 2 2 2 1 Nitrite/Sulfite reductase ferredoxin-like half domain Rubredoxin_C PF18267.1 KFY01031.1 - 3.4e-05 23.7 0.1 0.091 12.7 0.0 3.3 3 0 0 3 3 3 2 Rubredoxin NAD+ reductase C-terminal domain Amino_oxidase PF01593.24 KFY01031.1 - 0.0077 15.6 0.0 1.7 7.8 0.0 2.3 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase NAD_binding_9 PF13454.6 KFY01031.1 - 0.0088 16.0 1.4 5.7 6.9 0.0 3.3 4 0 0 4 4 4 2 FAD-NAD(P)-binding FAD_binding_2 PF00890.24 KFY01031.1 - 0.12 11.4 3.4 1.2 8.1 0.0 2.7 2 1 1 3 3 3 0 FAD binding domain GIDA PF01134.22 KFY01031.1 - 0.22 10.5 2.9 28 3.6 2.2 3.0 2 1 1 3 3 3 0 Glucose inhibited division protein A MFS_1 PF07690.16 KFY01032.1 - 2.8e-27 95.6 26.2 1.1e-24 87.0 10.8 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily LacY_symp PF01306.19 KFY01032.1 - 0.00063 18.6 10.0 0.72 8.6 3.0 3.2 2 1 1 3 3 3 3 LacY proton/sugar symporter Pox_A14 PF05767.12 KFY01032.1 - 0.071 13.3 0.1 0.19 11.9 0.1 1.7 1 0 0 1 1 1 0 Poxvirus virion envelope protein A14 DUF4282 PF14110.6 KFY01032.1 - 2.4 9.0 0.0 2.4 9.0 0.0 3.6 3 2 0 3 3 3 0 Domain of unknown function (DUF4282) GST_N_3 PF13417.6 KFY01033.1 - 3.3e-15 56.2 0.0 6e-15 55.4 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KFY01033.1 - 3.8e-11 43.1 0.0 9.1e-11 41.9 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 KFY01033.1 - 1.3e-10 41.4 0.1 2.8e-10 40.4 0.1 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 KFY01033.1 - 1.5e-09 37.9 0.0 2.6e-09 37.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KFY01033.1 - 7.4e-08 32.5 0.1 1.2e-07 31.9 0.1 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 KFY01033.1 - 6.2e-05 22.9 0.1 0.00014 21.9 0.0 1.6 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_5 PF16865.5 KFY01033.1 - 0.029 14.9 0.1 0.25 11.9 0.0 2.1 1 1 0 2 2 2 0 Glutathione S-transferase, C-terminal domain GST_N_4 PF17172.4 KFY01033.1 - 0.072 13.8 0.0 0.24 12.2 0.0 1.8 1 1 0 1 1 1 0 Glutathione S-transferase N-terminal domain Lipase_GDSL_2 PF13472.6 KFY01034.1 - 2.2e-10 41.2 0.9 3.4e-10 40.6 0.9 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family FANCL_C PF11793.8 KFY01035.1 - 0.0024 18.0 2.6 0.0024 18.0 2.6 2.8 3 0 0 3 3 3 1 FANCL C-terminal domain zf-RING_2 PF13639.6 KFY01035.1 - 0.0025 18.1 4.9 0.0025 18.1 4.9 4.2 3 1 1 4 4 4 1 Ring finger domain VWA_2 PF13519.6 KFY01035.1 - 0.0075 16.9 0.0 0.02 15.5 0.0 1.8 1 0 0 1 1 1 1 von Willebrand factor type A domain zf-4CXXC_R1 PF10497.9 KFY01035.1 - 0.015 15.5 2.3 0.015 15.5 2.3 3.2 2 1 1 3 3 3 0 Zinc-finger domain of monoamine-oxidase A repressor R1 Prok-RING_4 PF14447.6 KFY01035.1 - 3.9 7.4 9.6 0.059 13.2 1.4 2.4 2 1 0 2 2 2 0 Prokaryotic RING finger family 4 MFS_1 PF07690.16 KFY01036.1 - 1.1e-35 123.2 60.0 1.1e-33 116.7 60.0 2.3 1 1 0 1 1 1 1 Major Facilitator Superfamily DUF4442 PF14539.6 KFY01036.1 - 0.64 10.2 2.4 1.3 9.2 1.4 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4442) Acetyltransf_7 PF13508.7 KFY01037.1 - 1.8e-08 34.7 0.0 2.7e-08 34.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KFY01037.1 - 2e-07 31.2 0.1 2.5e-07 30.9 0.1 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KFY01037.1 - 2.4e-06 27.5 0.0 3.6e-06 26.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 KFY01037.1 - 0.0051 16.9 0.4 1.8 8.6 0.0 2.9 3 0 0 3 3 3 2 Acetyltransferase (GNAT) domain FR47 PF08445.10 KFY01037.1 - 0.19 11.7 0.0 0.3 11.1 0.0 1.4 1 0 0 1 1 1 0 FR47-like protein Ank_4 PF13637.6 KFY01041.1 - 2.6e-10 40.6 0.1 0.085 13.5 0.0 5.2 3 2 3 6 6 6 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFY01041.1 - 1.2e-07 31.4 0.3 1.1 10.0 0.0 5.4 6 1 0 6 6 6 3 Ankyrin repeat Ank PF00023.30 KFY01041.1 - 0.00084 19.7 0.0 8.5 7.0 0.0 4.2 4 0 0 4 4 4 2 Ankyrin repeat Ank_4 PF13637.6 KFY01042.1 - 2.5e-18 66.2 0.0 0.0092 16.5 0.0 5.9 5 1 1 6 6 6 4 Ankyrin repeats (many copies) Ank_2 PF12796.7 KFY01042.1 - 2.8e-12 47.0 0.0 0.00034 21.1 0.0 3.6 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Epimerase PF01370.21 KFY01042.1 - 4.4e-10 39.4 0.1 1.4e-09 37.8 0.1 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Ank_5 PF13857.6 KFY01042.1 - 1.5e-08 34.8 3.4 0.29 11.5 0.0 5.4 4 1 0 4 4 4 2 Ankyrin repeats (many copies) 3Beta_HSD PF01073.19 KFY01042.1 - 9.6e-07 28.1 0.0 1.7e-06 27.3 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NmrA PF05368.13 KFY01042.1 - 2.4e-06 27.3 0.4 5.7e-06 26.0 0.3 1.6 2 0 0 2 2 2 1 NmrA-like family Ank_3 PF13606.6 KFY01042.1 - 3.6e-06 26.9 2.5 23 6.0 0.0 6.8 6 1 0 6 6 6 0 Ankyrin repeat GDP_Man_Dehyd PF16363.5 KFY01042.1 - 7.4e-05 22.3 0.0 0.00013 21.5 0.0 1.4 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.12 KFY01042.1 - 0.00027 20.2 0.0 0.0035 16.5 0.0 2.1 1 1 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.6 KFY01042.1 - 0.00077 19.4 0.2 0.0014 18.6 0.2 1.4 1 0 0 1 1 1 1 NAD(P)H-binding Ank_2 PF12796.7 KFY01043.1 - 1.7e-25 89.4 0.2 1.1e-08 35.6 0.3 5.8 3 1 2 6 6 6 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KFY01043.1 - 2.4e-19 69.4 2.2 0.00019 21.9 0.8 7.1 5 1 1 6 6 6 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFY01043.1 - 1.9e-17 61.5 8.3 0.2 12.3 0.1 9.2 9 0 0 9 9 9 5 Ankyrin repeat Ank PF00023.30 KFY01043.1 - 3.9e-14 52.3 4.5 0.0072 16.7 0.2 7.1 7 0 0 7 7 7 4 Ankyrin repeat Ank_5 PF13857.6 KFY01043.1 - 2.3e-10 40.5 3.9 0.00028 21.1 0.1 5.5 4 1 0 5 5 5 2 Ankyrin repeats (many copies) F-box-like PF12937.7 KFY01043.1 - 0.00017 21.4 0.6 0.00066 19.5 0.3 2.1 2 0 0 2 2 2 1 F-box-like MFS_1 PF07690.16 KFY01044.1 - 3.2e-35 121.7 30.9 5.9e-35 120.8 30.7 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily Fungal_trans PF04082.18 KFY01045.1 - 1.1e-21 77.1 0.3 2e-20 72.9 0.3 2.2 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KFY01045.1 - 6.5e-06 26.2 6.2 1.1e-05 25.4 6.2 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF1445 PF07286.12 KFY01046.1 - 4.1e-62 208.3 0.0 5.4e-62 208.0 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1445) Hydantoinase_B PF02538.14 KFY01047.1 - 5.1e-218 724.7 0.2 6.9e-218 724.2 0.2 1.2 1 0 0 1 1 1 1 Hydantoinase B/oxoprolinase Hydantoinase_A PF01968.18 KFY01047.1 - 1.6e-102 342.7 0.5 3.2e-102 341.7 0.2 1.7 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.13 KFY01047.1 - 3e-55 186.7 1.7 4.1e-54 183.0 0.0 2.4 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase N-terminal region IGPD PF00475.18 KFY01047.1 - 0.19 12.0 0.2 11 6.3 0.0 2.5 2 0 0 2 2 2 0 Imidazoleglycerol-phosphate dehydratase CoA_binding_2 PF13380.6 KFY01048.1 - 3.8e-28 98.3 0.0 4.6e-28 98.0 0.0 1.1 1 0 0 1 1 1 1 CoA binding domain HET PF06985.11 KFY01049.1 - 2e-12 47.7 3.9 2.1e-09 37.9 0.4 2.5 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) Zn_clus PF00172.18 KFY01050.1 - 9.1e-05 22.5 8.7 0.00025 21.1 8.7 1.8 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DSBA PF01323.20 KFY01051.1 - 4.1e-32 111.5 0.0 5e-32 111.3 0.0 1.0 1 0 0 1 1 1 1 DSBA-like thioredoxin domain Thioredoxin_4 PF13462.6 KFY01051.1 - 0.00035 20.8 0.0 0.0014 18.8 0.0 1.8 2 0 0 2 2 2 1 Thioredoxin COesterase PF00135.28 KFY01052.1 - 2.9e-81 273.9 0.0 4.6e-81 273.2 0.0 1.2 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KFY01052.1 - 2.1e-05 24.5 0.3 9e-05 22.4 0.3 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Chlorophyllase2 PF12740.7 KFY01052.1 - 0.036 13.0 0.0 0.072 12.0 0.0 1.4 1 0 0 1 1 1 0 Chlorophyllase enzyme 5-FTHF_cyc-lig PF01812.20 KFY01053.1 - 5.1e-31 108.0 0.0 6.1e-31 107.7 0.0 1.1 1 0 0 1 1 1 1 5-formyltetrahydrofolate cyclo-ligase family CdiI_N PF18228.1 KFY01053.1 - 0.14 12.0 0.1 0.22 11.4 0.1 1.3 1 0 0 1 1 1 0 CdiI N-terminal domain Clathrin PF00637.20 KFY01068.1 - 4.8e-22 78.4 4.3 8.5e-21 74.3 2.4 2.4 2 0 0 2 2 2 1 Region in Clathrin and VPS VPS11_C PF12451.8 KFY01068.1 - 5e-11 42.7 0.0 1.2e-10 41.4 0.0 1.7 1 0 0 1 1 1 1 Vacuolar protein sorting protein 11 C terminal zf-C3H2C3 PF17122.5 KFY01068.1 - 2.2e-06 27.6 5.4 5.3e-06 26.4 5.4 1.7 1 0 0 1 1 1 1 Zinc-finger zf-ANAPC11 PF12861.7 KFY01068.1 - 0.00019 21.4 1.3 0.00044 20.2 1.3 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger TPR_14 PF13428.6 KFY01068.1 - 0.00059 20.4 1.6 1.8 9.6 0.0 4.0 3 1 1 4 4 3 1 Tetratricopeptide repeat PHD PF00628.29 KFY01068.1 - 0.00088 19.1 4.2 0.0023 17.8 4.2 1.8 1 0 0 1 1 1 1 PHD-finger TPR_11 PF13414.6 KFY01068.1 - 0.0017 18.0 0.2 0.0017 18.0 0.2 2.5 3 0 0 3 3 2 1 TPR repeat zf-RING_2 PF13639.6 KFY01068.1 - 0.002 18.4 6.5 0.0038 17.5 6.5 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 KFY01068.1 - 0.0023 17.7 6.8 0.0046 16.8 6.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KFY01068.1 - 0.0039 17.1 4.2 0.0076 16.2 4.2 1.5 1 0 0 1 1 1 1 zinc-RING finger domain TPR_2 PF07719.17 KFY01068.1 - 0.016 15.3 1.0 0.16 12.2 0.1 3.1 2 0 0 2 2 2 0 Tetratricopeptide repeat PHD_2 PF13831.6 KFY01068.1 - 0.017 14.6 1.5 0.048 13.2 1.5 1.8 1 0 0 1 1 1 0 PHD-finger DUF4810 PF16068.5 KFY01068.1 - 0.042 14.4 0.2 19 5.9 0.0 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4810) zf-C3HC4 PF00097.25 KFY01068.1 - 0.053 13.4 5.4 0.1 12.5 5.4 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) CdiI_2 PF18593.1 KFY01068.1 - 0.063 13.9 0.5 53 4.6 0.0 3.6 3 0 0 3 3 3 0 CdiI immunity protein zf-rbx1 PF12678.7 KFY01068.1 - 0.069 13.5 5.6 0.14 12.5 5.6 1.5 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 KFY01068.1 - 0.089 12.8 4.8 0.25 11.4 4.8 1.8 1 0 0 1 1 1 0 RING-type zinc-finger Vps39_2 PF10367.9 KFY01068.1 - 0.14 12.6 0.5 0.32 11.4 0.1 1.9 2 0 0 2 2 1 0 Vacuolar sorting protein 39 domain 2 KIP1 PF07765.12 KFY01068.1 - 0.25 11.5 1.3 0.94 9.6 0.3 2.4 2 0 0 2 2 2 0 KIP1-like protein TPR_1 PF00515.28 KFY01068.1 - 4.6 7.2 6.1 4.3 7.3 0.5 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat ANAPC3 PF12895.7 KFY01068.1 - 8.2 6.7 7.3 22 5.4 0.9 3.4 3 1 1 4 4 3 0 Anaphase-promoting complex, cyclosome, subunit 3 Band_7 PF01145.25 KFY01069.1 - 1.9e-16 60.6 0.1 1.9e-16 60.6 0.1 3.0 2 1 0 2 2 2 1 SPFH domain / Band 7 family FAM216B PF15107.6 KFY01069.1 - 0.18 11.7 1.1 7.1 6.5 0.0 3.0 2 1 1 3 3 3 0 FAM216B protein family WH2 PF02205.20 KFY01075.1 - 2.5e-05 24.0 0.9 5.7e-05 22.8 0.9 1.6 1 0 0 1 1 1 1 WH2 motif CAP_N PF01213.19 KFY01075.1 - 0.00086 18.9 4.0 0.00086 18.9 4.0 3.2 1 1 2 3 3 3 1 Adenylate cyclase associated (CAP) N terminal eIF-1a PF01176.19 KFY01076.1 - 2.1e-21 75.5 0.0 2.9e-21 75.0 0.0 1.2 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 zf-RVT PF13966.6 KFY01077.1 - 0.024 15.4 0.2 0.063 14.0 0.2 1.7 2 0 0 2 2 2 0 zinc-binding in reverse transcriptase fn3_2 PF16893.5 KFY01078.1 - 2.1e-39 133.5 0.0 3.7e-39 132.8 0.0 1.4 1 0 0 1 1 1 1 Fibronectin type III domain CHS5_N PF16892.5 KFY01078.1 - 4.6e-24 84.1 0.5 7.8e-24 83.4 0.5 1.4 1 0 0 1 1 1 1 Chitin biosynthesis protein CHS5 N-terminus PTCB-BRCT PF12738.7 KFY01078.1 - 5.7e-12 45.4 0.0 1e-11 44.6 0.0 1.5 1 0 0 1 1 1 1 twin BRCT domain BRCT PF00533.26 KFY01078.1 - 1.3e-08 35.1 0.0 2.4e-08 34.2 0.0 1.5 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain DUF3006 PF11213.8 KFY01078.1 - 0.00064 19.9 0.0 0.0017 18.6 0.0 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF3006) fn3 PF00041.21 KFY01078.1 - 0.0018 18.6 0.1 0.0075 16.6 0.1 2.0 1 1 0 1 1 1 1 Fibronectin type III domain BRCT_2 PF16589.5 KFY01078.1 - 0.0027 18.1 0.0 0.0061 16.9 0.0 1.5 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain SURF2 PF05477.11 KFY01078.1 - 0.11 12.2 4.0 0.16 11.6 4.0 1.2 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) adh_short PF00106.25 KFY01079.1 - 4.7e-07 29.5 0.0 6.5e-06 25.7 0.0 2.1 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KFY01079.1 - 0.0023 17.8 0.0 0.0037 17.2 0.0 1.3 1 0 0 1 1 1 1 KR domain CBM_6 PF03422.15 KFY01079.1 - 0.074 13.4 0.1 0.13 12.6 0.1 1.3 1 0 0 1 1 1 0 Carbohydrate binding module (family 6) SEN1_N PF12726.7 KFY01080.1 - 1.2e-199 665.3 1.6 1.6e-199 664.8 1.6 1.2 1 0 0 1 1 1 1 SEN1 N terminal AAA_11 PF13086.6 KFY01080.1 - 1.8e-69 234.4 0.6 1.8e-69 234.4 0.6 2.6 2 0 0 2 2 2 1 AAA domain AAA_12 PF13087.6 KFY01080.1 - 5.2e-58 196.0 0.0 9.9e-58 195.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 KFY01080.1 - 1.1e-07 31.8 0.0 0.00091 19.0 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.6 KFY01080.1 - 4.8e-07 30.2 0.0 1.8e-06 28.3 0.0 2.0 1 1 0 1 1 1 1 AAA domain UvrD-helicase PF00580.21 KFY01080.1 - 1.4e-06 28.0 0.0 0.00034 20.3 0.0 2.8 1 1 0 1 1 1 1 UvrD/REP helicase N-terminal domain Viral_helicase1 PF01443.18 KFY01080.1 - 3.3e-06 27.0 1.1 0.093 12.5 0.0 4.3 4 0 0 4 4 4 2 Viral (Superfamily 1) RNA helicase DEAD PF00270.29 KFY01080.1 - 0.025 14.4 0.1 0.11 12.3 0.0 2.0 2 0 0 2 2 2 0 DEAD/DEAH box helicase Annexin PF00191.20 KFY01080.1 - 0.47 10.6 2.1 0.8 9.8 0.0 2.6 3 0 0 3 3 3 0 Annexin PhoLip_ATPase_C PF16212.5 KFY01081.1 - 1.2e-81 274.2 26.0 1.2e-81 274.2 26.0 2.6 3 0 0 3 3 3 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 KFY01081.1 - 1.2e-19 69.8 0.4 1.2e-19 69.8 0.4 2.0 2 0 0 2 2 2 1 Phospholipid-translocating ATPase N-terminal Hydrolase PF00702.26 KFY01081.1 - 2.1e-12 47.8 3.8 1.4e-08 35.2 0.2 2.9 1 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 KFY01081.1 - 1.1e-11 44.7 0.0 4.7e-11 42.6 0.0 2.0 2 0 0 2 2 2 1 Cation transport ATPase (P-type) E1-E2_ATPase PF00122.20 KFY01081.1 - 9.3e-05 22.0 0.0 0.0023 17.5 0.0 2.7 2 1 0 2 2 2 1 E1-E2 ATPase Hydrolase_3 PF08282.12 KFY01081.1 - 0.02 14.6 0.2 0.062 13.0 0.2 1.8 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase AA_permease_C PF13906.6 KFY01081.1 - 0.55 10.3 8.1 2.1 8.5 8.1 2.1 1 0 0 1 1 1 0 C-terminus of AA_permease MFS_1 PF07690.16 KFY01085.1 - 2.7e-30 105.5 14.4 2.7e-30 105.5 14.4 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KFY01085.1 - 9e-08 31.4 9.5 9e-08 31.4 9.5 2.0 2 1 0 2 2 2 1 Sugar (and other) transporter MFS_5 PF05631.14 KFY01085.1 - 7.2e-05 21.9 0.6 0.00014 20.9 0.6 1.4 1 0 0 1 1 1 1 Sugar-tranasporters, 12 TM BTB PF00651.31 KFY01086.1 - 0.031 14.5 0.0 0.21 11.8 0.0 2.1 1 1 0 1 1 1 0 BTB/POZ domain APH PF01636.23 KFY01087.1 - 9.1e-07 29.0 0.0 3.8e-06 27.0 0.0 1.9 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KFY01087.1 - 2.8e-05 23.8 0.0 4.1e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase Pkinase PF00069.25 KFY01087.1 - 0.23 10.8 0.0 0.38 10.1 0.0 1.3 1 0 0 1 1 1 0 Protein kinase domain DSPc PF00782.20 KFY01088.1 - 5e-09 36.1 0.0 8.1e-09 35.4 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 KFY01088.1 - 0.0014 18.3 0.0 0.0021 17.7 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.6 KFY01088.1 - 0.02 14.9 0.0 0.029 14.3 0.0 1.2 1 0 0 1 1 1 0 Tyrosine phosphatase family DUF2655 PF10848.8 KFY01093.1 - 0.027 14.8 0.0 0.048 14.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2655) Dicty_REP PF05086.12 KFY01093.1 - 8 4.3 5.5 8.2 4.3 5.5 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Pkinase PF00069.25 KFY01094.1 - 4.9e-10 39.2 0.0 9.1e-10 38.3 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFY01094.1 - 0.04 13.2 0.0 0.058 12.7 0.0 1.4 1 0 0 1 1 1 0 Protein tyrosine kinase 4HBT_2 PF13279.6 KFY01096.1 - 5.5e-06 26.9 0.1 7e-06 26.5 0.1 1.2 1 0 0 1 1 1 1 Thioesterase-like superfamily Helo_like_N PF17111.5 KFY01097.1 - 1.4e-72 243.5 0.3 2.4e-72 242.7 0.3 1.4 1 0 0 1 1 1 1 Fungal N-terminal domain of STAND proteins SesA PF17107.5 KFY01097.1 - 0.0055 16.9 0.7 0.18 12.0 0.0 3.1 3 0 0 3 3 3 1 N-terminal domain on NACHT_NTPase and P-loop NTPases DUF1479 PF07350.12 KFY01107.1 - 5.6e-92 308.7 0.0 6.4e-92 308.5 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1479) Ceramidase_alk PF04734.13 KFY01108.1 - 3.2e-213 709.0 0.0 3.7e-213 708.8 0.0 1.0 1 0 0 1 1 1 1 Neutral/alkaline non-lysosomal ceramidase, N-terminal Ceramidse_alk_C PF17048.5 KFY01108.1 - 1.1e-59 201.1 0.0 2e-59 200.2 0.0 1.4 1 0 0 1 1 1 1 Neutral/alkaline non-lysosomal ceramidase, C-terminal FtsJ PF01728.19 KFY01109.1 - 2.9e-58 196.9 0.0 3.5e-58 196.6 0.0 1.1 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_23 PF13489.6 KFY01109.1 - 0.00025 20.9 0.0 0.00047 20.0 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KFY01109.1 - 0.003 17.4 0.0 0.03 14.1 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 KFY01109.1 - 0.12 13.1 0.0 0.52 11.0 0.0 2.1 2 0 0 2 2 2 0 Methyltransferase domain OST3_OST6 PF04756.13 KFY01110.1 - 2.3e-108 362.0 0.0 2.8e-108 361.7 0.0 1.0 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family HXXEE PF13787.6 KFY01110.1 - 0.058 14.2 1.7 0.081 13.7 0.2 1.9 2 0 0 2 2 2 0 Protein of unknown function with HXXEE motif VKOR PF07884.14 KFY01110.1 - 1.1 9.5 6.3 0.37 11.0 0.4 2.3 2 0 0 2 2 2 0 Vitamin K epoxide reductase family MerC PF03203.14 KFY01110.1 - 1.1 9.7 5.9 2.1 8.8 0.1 2.5 2 0 0 2 2 2 0 MerC mercury resistance protein DUF5401 PF17380.2 KFY01111.1 - 0.00014 20.1 27.0 0.0002 19.6 27.0 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF5401) PEX-2N PF09263.10 KFY01111.1 - 1.7 9.0 5.3 8.1 6.8 1.6 2.3 1 1 1 2 2 2 0 Peroxisome biogenesis factor 1, N-terminal DUF3019 PF11456.8 KFY01111.1 - 5 7.7 11.8 22 5.6 3.6 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF3019) Rft-1 PF04506.13 KFY01112.1 - 6.1e-147 490.5 19.0 6.8e-147 490.3 19.0 1.0 1 0 0 1 1 1 1 Rft protein Polysacc_synt_3 PF13440.6 KFY01112.1 - 0.0036 16.5 11.4 0.0036 16.5 11.4 2.8 2 1 0 2 2 2 1 Polysaccharide biosynthesis protein FixQ PF05545.11 KFY01112.1 - 1.6 8.8 5.4 21 5.2 0.5 3.5 3 0 0 3 3 3 0 Cbb3-type cytochrome oxidase component FixQ DEAD PF00270.29 KFY01113.1 - 1e-52 178.5 0.0 2.7e-52 177.1 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KFY01113.1 - 3.2e-33 114.4 0.0 2.3e-30 105.2 0.0 2.7 3 0 0 3 3 3 2 Helicase conserved C-terminal domain ResIII PF04851.15 KFY01113.1 - 1.4e-08 35.0 0.3 4e-08 33.5 0.0 1.9 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit SWI2_SNF2 PF18766.1 KFY01113.1 - 0.0004 20.1 0.0 0.00083 19.1 0.0 1.5 1 0 0 1 1 1 1 SWI2/SNF2 ATPase SecA_DEAD PF07517.14 KFY01113.1 - 0.0013 18.1 1.6 0.0048 16.2 1.6 2.0 1 1 0 1 1 1 1 SecA DEAD-like domain ERCC3_RAD25_C PF16203.5 KFY01113.1 - 0.0058 15.9 0.0 0.0058 15.9 0.0 1.8 2 0 0 2 2 2 1 ERCC3/RAD25/XPB C-terminal helicase UTP25 PF06862.12 KFY01113.1 - 0.014 14.2 0.0 0.34 9.6 0.0 2.7 2 1 1 3 3 3 0 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 CMS1 PF14617.6 KFY01113.1 - 0.052 12.9 0.0 0.052 12.9 0.0 2.8 2 1 1 3 3 2 0 U3-containing 90S pre-ribosomal complex subunit AAA_22 PF13401.6 KFY01113.1 - 0.087 13.1 0.7 1.6 9.0 0.8 2.6 1 1 0 1 1 1 0 AAA domain TFIIF_alpha PF05793.12 KFY01113.1 - 1 7.9 19.5 1.5 7.3 19.5 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) SOG2 PF10428.9 KFY01113.1 - 2.2 7.4 8.5 3.2 6.8 8.5 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein Draxin PF15550.6 KFY01113.1 - 2.3 8.0 10.4 3.9 7.3 10.4 1.3 1 0 0 1 1 1 0 Draxin RR_TM4-6 PF06459.12 KFY01113.1 - 5.5 6.7 14.3 8.5 6.1 14.3 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 NifU_N PF01592.16 KFY01114.1 - 1.9e-52 176.8 0.0 2.5e-52 176.4 0.0 1.2 1 0 0 1 1 1 1 NifU-like N terminal domain TSCPD PF12637.7 KFY01114.1 - 0.12 12.6 0.0 0.23 11.8 0.0 1.4 1 0 0 1 1 1 0 TSCPD domain UCH PF00443.29 KFY01115.1 - 2.4e-35 122.3 0.0 3.6e-35 121.7 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.19 KFY01115.1 - 1.9e-23 82.6 13.3 4.2e-19 68.6 2.9 3.5 3 0 0 3 3 3 2 Zn-finger in ubiquitin-hydrolases and other protein zf-UBP_var PF17807.1 KFY01115.1 - 2.7e-22 78.3 0.1 2.7e-22 78.3 0.1 3.0 4 0 0 4 4 4 1 Variant UBP zinc finger UBA PF00627.31 KFY01115.1 - 7.6e-22 76.8 0.3 4.3e-10 39.3 0.2 2.6 2 0 0 2 2 2 2 UBA/TS-N domain UCH_1 PF13423.6 KFY01115.1 - 7.3e-17 61.9 0.0 5.4e-16 59.1 0.0 2.4 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase HOIP-UBA PF16678.5 KFY01115.1 - 0.01 15.8 0.0 0.033 14.2 0.0 1.8 1 0 0 1 1 1 0 HOIP UBA domain pair UBA_4 PF14555.6 KFY01115.1 - 0.042 13.7 0.0 0.083 12.7 0.0 1.5 1 0 0 1 1 1 0 UBA-like domain Rax2 PF12768.7 KFY01116.1 - 8.3e-78 260.7 1.0 6.3e-77 257.9 0.0 2.9 3 0 0 3 3 3 1 Cortical protein marker for cell polarity DUF5122 PF17164.4 KFY01116.1 - 0.0064 16.8 11.8 0.17 12.2 0.1 5.3 5 0 0 5 5 5 2 Domain of unknown function (DUF5122) beta-propeller Kelch_4 PF13418.6 KFY01116.1 - 0.07 13.2 3.9 0.12 12.4 0.4 3.4 3 0 0 3 3 3 0 Galactose oxidase, central domain SNase PF00565.17 KFY01117.1 - 3.3e-23 82.2 0.1 5e-23 81.6 0.1 1.3 1 0 0 1 1 1 1 Staphylococcal nuclease homologue P34-Arc PF04045.14 KFY01118.1 - 7.3e-107 356.5 0.3 8.9e-107 356.3 0.3 1.1 1 0 0 1 1 1 1 Arp2/3 complex, 34 kD subunit p34-Arc ARPC4 PF05856.12 KFY01118.1 - 0.02 14.5 0.1 0.042 13.5 0.1 1.5 1 0 0 1 1 1 0 ARP2/3 complex 20 kDa subunit (ARPC4) Radical_SAM PF04055.21 KFY01118.1 - 0.18 12.2 1.5 2.9 8.2 0.4 2.3 1 1 1 2 2 2 0 Radical SAM superfamily WD40 PF00400.32 KFY01119.1 - 2.4e-48 161.1 26.1 3.5e-06 27.6 0.1 12.3 12 1 0 12 12 12 10 WD domain, G-beta repeat APH PF01636.23 KFY01119.1 - 9.8e-41 140.2 0.0 1.8e-40 139.4 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family ANAPC4_WD40 PF12894.7 KFY01119.1 - 8.5e-20 70.9 5.4 0.012 15.8 0.0 9.3 5 4 3 9 9 9 6 Anaphase-promoting complex subunit 4 WD40 domain Utp12 PF04003.12 KFY01119.1 - 8.9e-20 71.0 1.2 1.8e-19 70.0 1.2 1.5 1 0 0 1 1 1 1 Dip2/Utp12 Family Ge1_WD40 PF16529.5 KFY01119.1 - 8.2e-07 28.3 1.2 1.3 7.9 0.0 5.5 4 2 2 6 6 6 2 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 KFY01119.1 - 0.0012 18.2 0.0 2.3 7.4 0.0 3.3 3 0 0 3 3 3 2 WD40-like domain Nup160 PF11715.8 KFY01119.1 - 0.0064 15.2 3.8 0.28 9.8 0.0 4.4 5 1 0 5 5 5 1 Nucleoporin Nup120/160 EcKinase PF02958.20 KFY01119.1 - 0.0099 15.2 0.0 0.021 14.1 0.0 1.5 1 0 0 1 1 1 1 Ecdysteroid kinase Kdo PF06293.14 KFY01119.1 - 0.01 15.2 0.1 0.066 12.6 0.0 2.3 3 0 0 3 3 3 0 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 KFY01119.1 - 0.012 15.2 0.0 0.11 12.0 0.0 2.3 2 0 0 2 2 2 0 RIO1 family DUF1679 PF07914.11 KFY01119.1 - 0.017 14.0 0.0 0.054 12.3 0.0 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1679) Nucleoporin_N PF08801.11 KFY01119.1 - 0.045 12.5 0.2 3.5 6.3 0.0 3.5 3 1 0 3 3 3 0 Nup133 N terminal like eIF2A PF08662.11 KFY01119.1 - 0.092 12.6 0.0 0.99 9.2 0.0 2.7 2 1 1 3 3 3 0 Eukaryotic translation initiation factor eIF2A HECT PF00632.25 KFY01124.1 - 3.7e-67 227.0 0.0 5e-67 226.6 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) C1_1 PF00130.22 KFY01124.1 - 0.048 13.5 0.4 0.12 12.3 0.4 1.6 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) MMR_HSR1 PF01926.23 KFY01125.1 - 0.00014 21.9 0.1 0.012 15.7 0.1 2.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase Ribosomal_L16 PF00252.18 KFY01126.1 - 5.6e-30 104.0 0.1 7.1e-30 103.7 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e RFC1 PF08519.12 KFY01127.1 - 1.1e-60 204.4 0.4 3.3e-59 199.6 0.0 2.6 2 0 0 2 2 2 1 Replication factor RFC1 C terminal domain BRCT PF00533.26 KFY01127.1 - 9.2e-15 54.8 0.0 2.1e-14 53.7 0.0 1.7 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain AAA PF00004.29 KFY01127.1 - 4.6e-08 33.6 0.1 2.1e-07 31.4 0.0 2.2 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 KFY01127.1 - 2.9e-07 30.6 0.0 6.2e-07 29.5 0.0 1.5 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_22 PF13401.6 KFY01127.1 - 4.7e-05 23.7 0.0 0.00015 22.1 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 KFY01127.1 - 0.00019 22.0 0.7 0.016 15.8 0.0 3.1 2 0 0 2 2 2 1 AAA domain AAA_24 PF13479.6 KFY01127.1 - 0.0034 17.1 0.0 0.0088 15.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KFY01127.1 - 0.015 15.7 1.3 0.11 12.9 0.0 2.7 2 1 0 2 2 2 0 AAA ATPase domain AAA_28 PF13521.6 KFY01127.1 - 0.018 15.3 0.5 0.11 12.7 0.0 2.5 3 0 0 3 3 2 0 AAA domain DNA_pol3_delta PF06144.13 KFY01127.1 - 0.024 14.4 0.0 0.064 13.0 0.0 1.8 1 0 0 1 1 1 0 DNA polymerase III, delta subunit AAA_14 PF13173.6 KFY01127.1 - 0.036 14.1 0.0 0.12 12.4 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_assoc_2 PF16193.5 KFY01127.1 - 0.056 13.8 2.2 0.25 11.7 0.0 3.0 3 0 0 3 3 2 0 AAA C-terminal domain AAA_33 PF13671.6 KFY01127.1 - 0.082 13.1 1.9 0.19 11.9 0.0 2.5 3 0 0 3 3 3 0 AAA domain RuvB_N PF05496.12 KFY01127.1 - 0.088 12.5 0.0 0.17 11.6 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain RNA_helicase PF00910.22 KFY01127.1 - 0.12 12.8 0.0 0.36 11.2 0.0 1.9 1 0 0 1 1 1 0 RNA helicase AAA_17 PF13207.6 KFY01127.1 - 0.86 10.0 9.0 1.2 9.6 0.0 4.3 4 0 0 4 4 4 0 AAA domain DDE_Tnp_IS66 PF03050.14 KFY01127.1 - 2.1 7.7 6.6 0.5 9.8 0.1 2.4 2 0 0 2 2 2 0 Transposase IS66 family ATPase_2 PF01637.18 KFY01127.1 - 3.3 7.5 8.6 10 5.9 2.5 3.3 2 1 0 2 2 2 0 ATPase domain predominantly from Archaea tRNA-synt_2d PF01409.20 KFY01129.1 - 1.3e-46 159.1 1.1 4.1e-24 85.4 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) GrpE PF01025.19 KFY01129.1 - 4.1e-42 143.7 4.4 7.4e-42 142.8 4.4 1.4 1 0 0 1 1 1 1 GrpE FDX-ACB PF03147.14 KFY01129.1 - 1.1e-26 93.1 0.1 3e-26 91.7 0.0 1.8 2 0 0 2 2 2 1 Ferredoxin-fold anticodon binding domain Tai4 PF16695.5 KFY01129.1 - 0.16 12.5 1.1 0.41 11.2 1.1 1.8 1 0 0 1 1 1 0 Type VI secretion system (T6SS), amidase immunity protein Mito_carr PF00153.27 KFY01130.1 - 2.4e-59 197.3 1.1 3.1e-21 75.1 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein RNA_pol_A_bac PF01000.26 KFY01131.1 - 2.9e-32 111.3 0.0 5.2e-32 110.5 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.24 KFY01131.1 - 1.3e-18 66.1 0.0 1.7e-18 65.8 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain GAS PF13851.6 KFY01146.1 - 0.018 14.4 7.3 0.045 13.1 7.0 1.9 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding TetR_C_24 PF17932.1 KFY01146.1 - 0.024 14.9 0.6 6.1 7.1 0.0 2.4 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain DUF3618 PF12277.8 KFY01146.1 - 0.052 13.8 0.4 0.14 12.4 0.4 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3618) DUF1664 PF07889.12 KFY01146.1 - 0.094 12.8 0.6 1.4 8.9 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) KfrA_N PF11740.8 KFY01146.1 - 0.11 13.2 4.6 0.47 11.1 1.0 2.3 2 0 0 2 2 2 0 Plasmid replication region DNA-binding N-term HALZ PF02183.18 KFY01146.1 - 0.46 10.7 7.0 3.7 7.8 0.1 3.2 3 0 0 3 3 3 0 Homeobox associated leucine zipper kleA_kleC PF17383.2 KFY01146.1 - 0.97 9.8 4.9 0.71 10.2 0.2 2.6 3 0 0 3 3 3 0 Uncharacterized KorC regulated protein A PRKG1_interact PF15898.5 KFY01146.1 - 4.6 8.2 9.9 0.99 10.3 0.6 2.5 2 1 0 2 2 2 0 cGMP-dependent protein kinase interacting domain Nup54 PF13874.6 KFY01146.1 - 7.9 6.6 8.0 5.3 7.2 0.6 2.3 2 1 1 3 3 3 0 Nucleoporin complex subunit 54 NeuB PF03102.14 KFY01147.1 - 0.0079 15.7 0.1 0.025 14.1 0.0 1.8 2 0 0 2 2 2 1 NeuB family NUC173 PF08161.12 KFY01147.1 - 0.0094 15.6 0.0 0.66 9.6 0.0 2.5 2 0 0 2 2 2 1 NUC173 domain Csm2_III-A PF03750.13 KFY01147.1 - 0.039 14.8 0.0 0.16 12.8 0.0 2.1 1 0 0 1 1 1 0 Csm2 Type III-A Methyltransf_FA PF12248.8 KFY01147.1 - 0.11 12.9 0.0 0.65 10.4 0.0 2.2 2 0 0 2 2 2 0 Farnesoic acid 0-methyl transferase Zn_clus PF00172.18 KFY01149.1 - 1.5e-13 50.6 46.0 1.2e-05 25.3 13.9 3.5 3 0 0 3 3 3 3 Fungal Zn(2)-Cys(6) binuclear cluster domain PSI_integrin PF17205.3 KFY01149.1 - 0.0052 16.5 2.2 0.0052 16.5 2.2 3.3 2 1 1 3 3 3 1 Integrin plexin domain Tropomyosin_1 PF12718.7 KFY01150.1 - 0.091 12.9 0.1 0.17 12.0 0.1 1.4 1 0 0 1 1 1 0 Tropomyosin like SNARE PF05739.19 KFY01150.1 - 3.3 7.8 4.7 0.6 10.1 0.5 1.9 2 0 0 2 2 2 0 SNARE domain Motilin_assoc PF04643.12 KFY01150.1 - 9.7 6.1 7.0 5.6 6.9 0.0 3.0 3 1 0 3 3 3 0 Motilin/ghrelin-associated peptide Pkinase_Tyr PF07714.17 KFY01152.1 - 3.1e-25 89.0 0.0 4.3e-25 88.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KFY01152.1 - 1.5e-24 86.8 0.0 2e-24 86.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.6 KFY01152.1 - 0.00023 20.6 0.0 0.00032 20.1 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 KFY01152.1 - 0.0031 16.9 0.0 0.0045 16.4 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Chromo PF00385.24 KFY01153.1 - 6.6e-15 54.8 4.5 5.5e-08 32.6 0.9 2.7 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain Mtf2_C PF14061.6 KFY01153.1 - 0.33 11.1 2.7 1.1 9.5 0.1 2.3 2 0 0 2 2 2 0 Polycomb-like MTF2 factor 2 CBM_1 PF00734.18 KFY01162.1 - 5.5e-09 35.8 13.7 5.5e-09 35.8 13.7 2.3 2 0 0 2 2 2 1 Fungal cellulose binding domain FAD_binding_3 PF01494.19 KFY01163.1 - 4.3e-79 266.3 0.0 5.5e-79 266.0 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.12 KFY01163.1 - 3.4e-48 163.8 0.0 9.5e-48 162.4 0.0 1.8 2 0 0 2 2 2 1 Phenol hydroxylase, C-terminal dimerisation domain FAD_binding_2 PF00890.24 KFY01163.1 - 3.6e-05 23.0 0.2 0.00048 19.3 0.1 2.2 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.14 KFY01163.1 - 0.0026 17.0 0.0 0.0064 15.8 0.0 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 KFY01163.1 - 0.0034 16.8 0.4 0.0054 16.1 0.1 1.6 2 1 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.17 KFY01163.1 - 0.0036 16.6 0.0 0.0062 15.8 0.0 1.3 1 0 0 1 1 1 1 Thi4 family Trp_halogenase PF04820.14 KFY01163.1 - 0.015 14.1 0.1 0.025 13.5 0.1 1.3 1 0 0 1 1 1 0 Tryptophan halogenase SE PF08491.10 KFY01163.1 - 0.026 13.6 0.0 2.9 6.9 0.0 2.1 2 0 0 2 2 2 0 Squalene epoxidase DAO PF01266.24 KFY01163.1 - 0.054 13.1 1.5 0.33 10.5 0.3 2.2 1 1 1 2 2 2 0 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KFY01163.1 - 0.076 13.2 0.2 0.28 11.5 0.2 2.0 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain DUF3435 PF11917.8 KFY01170.1 - 0.0069 15.4 0.1 0.0069 15.4 0.1 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF3435) Vta1_C PF18097.1 KFY01170.1 - 0.1 12.3 0.0 0.29 10.9 0.0 1.7 1 0 0 1 1 1 0 Vta1 C-terminal domain Sec16_C PF12931.7 KFY01177.1 - 4.7e-111 371.3 0.0 6.4e-111 370.8 0.0 1.2 1 0 0 1 1 1 1 Sec23-binding domain of Sec16 Sec16 PF12932.7 KFY01177.1 - 1.7e-34 118.9 0.0 5.6e-34 117.3 0.0 2.0 1 0 0 1 1 1 1 Vesicle coat trafficking protein Sec16 mid-region Sec16_N PF12935.7 KFY01177.1 - 4.3e-11 43.4 11.8 4.3e-11 43.4 11.8 3.3 2 0 0 2 2 2 1 Vesicle coat trafficking protein Sec16 N-terminus Tim54 PF11711.8 KFY01177.1 - 0.6 8.8 3.3 38 2.9 0.0 2.4 2 0 0 2 2 2 0 Inner membrane protein import complex subunit Tim54 PhoLip_ATPase_C PF16212.5 KFY01178.1 - 2.2e-51 175.0 6.1 2.2e-51 175.0 6.1 2.2 2 0 0 2 2 2 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 KFY01178.1 - 2.8e-16 59.0 0.1 6.3e-16 57.8 0.1 1.6 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal Hydrolase PF00702.26 KFY01178.1 - 4.1e-13 50.1 3.1 6.5e-07 29.8 2.7 3.3 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 KFY01178.1 - 3.7e-06 26.9 0.0 9.2e-05 22.5 0.0 2.4 2 0 0 2 2 2 1 Cation transport ATPase (P-type) E1-E2_ATPase PF00122.20 KFY01178.1 - 1.5e-05 24.6 3.8 0.0046 16.5 0.0 2.6 2 0 0 2 2 2 2 E1-E2 ATPase Hydrolase_3 PF08282.12 KFY01178.1 - 0.00087 19.1 0.0 0.0017 18.1 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase 2-Hacid_dh_C PF02826.19 KFY01179.1 - 2.5e-50 170.3 0.0 4.7e-50 169.4 0.0 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 KFY01179.1 - 4.7e-15 55.4 0.0 7.8e-15 54.7 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain Methyltransf_25 PF13649.6 KFY01179.1 - 6.6e-08 33.2 0.0 8.5e-07 29.6 0.0 2.6 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 KFY01179.1 - 2.6e-07 30.5 0.0 1.2e-06 28.4 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.14 KFY01179.1 - 2e-06 27.4 0.0 0.00023 20.7 0.0 3.1 2 1 0 2 2 2 1 Methyltransferase small domain Methyltransf_11 PF08241.12 KFY01179.1 - 0.00047 20.8 0.0 0.0044 17.6 0.0 2.5 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 KFY01179.1 - 0.0017 19.0 0.0 0.0073 17.0 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain PrmC_N PF17827.1 KFY01179.1 - 0.004 17.7 0.1 0.042 14.4 0.1 2.6 2 1 0 2 2 2 1 PrmC N-terminal domain N6_Mtase PF02384.16 KFY01179.1 - 0.013 14.8 0.0 0.021 14.1 0.0 1.3 1 0 0 1 1 1 0 N-6 DNA Methylase Ubie_methyltran PF01209.18 KFY01179.1 - 0.13 11.6 0.0 0.25 10.7 0.0 1.4 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Suc_Fer-like PF06999.12 KFY01180.1 - 3.9e-28 98.6 0.0 4.7e-28 98.4 0.0 1.0 1 0 0 1 1 1 1 Sucrase/ferredoxin-like DSPc PF00782.20 KFY01189.1 - 4.3e-24 84.8 0.0 6e-24 84.4 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Init_tRNA_PT PF04179.12 KFY01189.1 - 2.8e-05 24.4 0.0 4.5e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 Rit1 DUSP-like domain Y_phosphatase3 PF13350.6 KFY01189.1 - 0.028 14.4 0.0 0.042 13.8 0.0 1.2 1 0 0 1 1 1 0 Tyrosine phosphatase family PTPlike_phytase PF14566.6 KFY01189.1 - 0.18 11.9 0.0 0.32 11.1 0.0 1.3 1 0 0 1 1 1 0 Inositol hexakisphosphate Ndc1_Nup PF09531.10 KFY01190.1 - 1.9e-194 647.8 0.0 2.2e-194 647.6 0.0 1.0 1 0 0 1 1 1 1 Nucleoporin protein Ndc1-Nup zf-Di19 PF05605.12 KFY01197.1 - 0.0064 16.8 2.5 0.011 16.0 2.5 1.3 1 0 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding zf-C2H2 PF00096.26 KFY01197.1 - 0.013 16.0 1.9 0.023 15.1 1.9 1.5 1 0 0 1 1 1 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFY01197.1 - 0.016 16.0 1.8 0.031 15.1 1.8 1.5 1 0 0 1 1 1 0 C2H2-type zinc finger zf-C2H2_3rep PF18868.1 KFY01197.1 - 0.1 13.3 0.0 0.15 12.8 0.0 1.2 1 0 0 1 1 1 0 Zinc finger C2H2-type, 3 repeats AAA PF00004.29 KFY01209.1 - 6.6e-48 162.5 0.0 1.3e-42 145.3 0.0 2.7 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 KFY01209.1 - 2e-05 24.4 0.0 0.00048 19.9 0.0 2.6 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 KFY01209.1 - 2.6e-05 24.7 0.1 0.026 14.9 0.0 3.9 3 1 0 3 3 3 1 AAA ATPase domain Parvo_NS1 PF01057.17 KFY01209.1 - 0.00049 19.3 0.0 0.00094 18.3 0.0 1.3 1 0 0 1 1 1 1 Parvovirus non-structural protein NS1 RNA_helicase PF00910.22 KFY01209.1 - 0.0019 18.6 0.0 0.012 16.0 0.0 2.4 2 0 0 2 2 2 1 RNA helicase AAA_25 PF13481.6 KFY01209.1 - 0.0026 17.3 0.0 0.013 15.1 0.0 2.2 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 KFY01209.1 - 0.0049 16.6 0.0 0.013 15.3 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_2 PF07724.14 KFY01209.1 - 0.005 17.0 0.0 0.013 15.6 0.0 1.7 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 KFY01209.1 - 0.0077 16.5 0.5 0.045 14.0 0.0 2.6 2 1 1 3 3 2 1 AAA domain TIP49 PF06068.13 KFY01209.1 - 0.011 15.0 0.0 0.019 14.2 0.0 1.3 1 0 0 1 1 1 0 TIP49 P-loop domain AAA_lid_3 PF17862.1 KFY01209.1 - 0.016 15.0 5.7 1 9.2 0.0 3.8 3 0 0 3 3 3 0 AAA+ lid domain ATPase PF06745.13 KFY01209.1 - 0.02 14.3 0.0 0.043 13.2 0.0 1.5 1 0 0 1 1 1 0 KaiC Mg_chelatase PF01078.21 KFY01209.1 - 0.021 14.2 0.0 0.045 13.1 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI MSP1_C PF07462.11 KFY01209.1 - 0.025 13.3 0.6 0.041 12.6 0.6 1.3 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus Vps4_C PF09336.10 KFY01209.1 - 0.039 14.0 0.1 0.56 10.2 0.1 2.7 2 0 0 2 2 2 0 Vps4 C terminal oligomerisation domain AAA_5 PF07728.14 KFY01209.1 - 0.04 13.9 0.0 0.14 12.1 0.0 2.0 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_18 PF13238.6 KFY01209.1 - 0.045 14.3 0.0 0.12 12.9 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 KFY01209.1 - 0.056 13.6 0.0 0.32 11.2 0.0 2.4 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 KFY01209.1 - 0.056 13.4 0.0 0.17 11.9 0.0 1.7 2 0 0 2 2 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_7 PF12775.7 KFY01209.1 - 0.058 12.9 0.0 0.11 12.0 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region PhoH PF02562.16 KFY01209.1 - 0.071 12.6 0.0 0.16 11.4 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein AAA_28 PF13521.6 KFY01209.1 - 0.11 12.7 0.0 0.26 11.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.22 KFY01209.1 - 0.11 11.6 0.0 3.5 6.7 0.0 2.7 3 0 0 3 3 3 0 NB-ARC domain HATPase_c_2 PF13581.6 KFY01210.1 - 0.025 14.5 0.0 0.043 13.8 0.0 1.3 1 0 0 1 1 1 0 Histidine kinase-like ATPase domain BTB PF00651.31 KFY01211.1 - 2e-05 24.8 0.7 0.1 12.8 0.1 3.1 2 1 1 3 3 3 2 BTB/POZ domain Alpha-amylase PF00128.24 KFY01212.1 - 1.3e-54 186.0 0.0 1.8e-54 185.6 0.0 1.2 1 0 0 1 1 1 1 Alpha amylase, catalytic domain DUF1966 PF09260.11 KFY01212.1 - 3.6e-22 78.4 0.0 7.6e-22 77.4 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1966) Aminotran_5 PF00266.19 KFY01212.1 - 0.13 11.1 0.0 0.2 10.5 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class-V Hydrolase_3 PF08282.12 KFY01213.1 - 1.6e-12 47.7 0.0 1.8e-11 44.3 0.0 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase PMM PF03332.13 KFY01213.1 - 2.1e-10 40.8 0.0 2.5e-10 40.5 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic phosphomannomutase Hydrolase PF00702.26 KFY01213.1 - 0.001 19.4 0.0 0.011 16.1 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase S6PP PF05116.13 KFY01213.1 - 0.015 14.8 0.0 0.098 12.2 0.0 2.1 2 1 0 2 2 2 0 Sucrose-6F-phosphate phosphohydrolase Trehalose_PPase PF02358.16 KFY01213.1 - 0.041 13.0 0.0 0.061 12.4 0.0 1.4 1 1 0 1 1 1 0 Trehalose-phosphatase adh_short_C2 PF13561.6 KFY01214.1 - 3.5e-55 187.1 4.8 6e-55 186.4 4.8 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KFY01214.1 - 1.8e-42 145.0 6.0 2.8e-42 144.4 6.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase APH PF01636.23 KFY01215.1 - 3.2e-13 50.2 0.0 4.5e-13 49.7 0.0 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KFY01215.1 - 1.4e-06 28.1 0.0 3.3e-06 26.8 0.0 1.5 1 1 0 1 1 1 1 Choline/ethanolamine kinase Pkinase PF00069.25 KFY01215.1 - 0.084 12.2 0.0 2.6 7.4 0.0 2.1 2 0 0 2 2 2 0 Protein kinase domain Amidohydro_2 PF04909.14 KFY01216.1 - 1.3e-17 64.6 0.0 1.4e-17 64.4 0.0 1.0 1 0 0 1 1 1 1 Amidohydrolase TPR_1 PF00515.28 KFY01224.1 - 1.9e-21 74.9 1.7 2.7e-05 23.8 0.0 5.7 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_2 PF07719.17 KFY01224.1 - 3.3e-19 67.4 6.3 8.6e-05 22.4 0.1 6.1 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_16 PF13432.6 KFY01224.1 - 5.8e-15 55.7 9.0 8.8e-06 26.3 0.3 4.4 3 1 1 4 4 4 4 Tetratricopeptide repeat TPR_14 PF13428.6 KFY01224.1 - 2.7e-14 52.7 6.1 0.00033 21.2 0.4 6.0 4 1 2 6 6 5 3 Tetratricopeptide repeat TPR_8 PF13181.6 KFY01224.1 - 3.2e-14 51.9 2.5 0.00028 20.9 0.0 5.4 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_11 PF13414.6 KFY01224.1 - 7.8e-13 47.9 5.5 7.7e-05 22.3 0.0 5.6 4 2 2 6 6 6 2 TPR repeat TPR_19 PF14559.6 KFY01224.1 - 5.4e-12 46.0 8.7 0.0027 18.2 0.1 5.0 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_12 PF13424.6 KFY01224.1 - 6e-11 42.5 4.8 5.6e-06 26.6 0.0 4.0 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_7 PF13176.6 KFY01224.1 - 5.6e-10 38.5 6.4 0.02 14.9 0.1 6.0 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_17 PF13431.6 KFY01224.1 - 6.3e-09 35.6 0.3 1.6 9.3 0.0 5.1 5 0 0 5 5 4 3 Tetratricopeptide repeat TPR_9 PF13371.6 KFY01224.1 - 9.2e-08 32.1 1.8 0.019 15.1 0.1 3.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_20 PF14561.6 KFY01224.1 - 2.1e-07 31.1 4.3 0.008 16.5 0.0 4.2 4 1 0 4 4 4 2 Tetratricopeptide repeat ANAPC3 PF12895.7 KFY01224.1 - 5.6e-06 26.5 2.1 0.00042 20.5 0.2 2.7 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_3 PF07720.12 KFY01224.1 - 0.0059 16.6 0.0 8.2 6.5 0.1 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat NatB_MDM20 PF09797.9 KFY01224.1 - 0.0069 15.4 0.0 0.018 14.0 0.0 1.6 2 0 0 2 2 2 1 N-acetyltransferase B complex (NatB) non catalytic subunit TPR_6 PF13174.6 KFY01224.1 - 0.0079 16.8 9.9 27 5.7 0.0 6.6 7 0 0 7 7 6 0 Tetratricopeptide repeat TPR_10 PF13374.6 KFY01224.1 - 0.02 14.7 0.5 0.02 14.7 0.5 4.5 5 0 0 5 5 4 0 Tetratricopeptide repeat DUF1641 PF07849.11 KFY01224.1 - 0.075 12.9 0.1 0.15 11.9 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1641) TPR_15 PF13429.6 KFY01224.1 - 0.35 10.0 8.4 1.7 7.8 0.3 2.9 3 1 0 3 3 3 0 Tetratricopeptide repeat BTAD PF03704.17 KFY01224.1 - 0.51 10.8 4.6 29 5.1 0.1 3.4 2 1 1 3 3 3 0 Bacterial transcriptional activator domain Glyco_hydro_16 PF00722.21 KFY01225.1 - 1.3e-08 34.6 0.1 6.5e-08 32.2 0.0 2.0 2 0 0 2 2 2 1 Glycosyl hydrolases family 16 XFP_N PF09364.10 KFY01239.1 - 5.8e-171 568.2 0.0 7.8e-171 567.8 0.0 1.2 1 0 0 1 1 1 1 XFP N-terminal domain XFP_C PF09363.10 KFY01239.1 - 1.3e-84 282.7 0.0 1.9e-84 282.2 0.0 1.2 1 0 0 1 1 1 1 XFP C-terminal domain XFP PF03894.15 KFY01239.1 - 8.2e-79 263.4 0.0 1.3e-78 262.7 0.0 1.3 1 0 0 1 1 1 1 D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase Fructosamin_kin PF03881.14 KFY01240.1 - 1.9e-20 73.3 0.0 2.3e-20 73.0 0.0 1.0 1 0 0 1 1 1 1 Fructosamine kinase Sugar_tr PF00083.24 KFY01241.1 - 1.5e-114 383.3 24.8 1.9e-114 383.1 24.8 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KFY01241.1 - 2.1e-15 56.5 38.2 3.5e-11 42.6 17.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily GFA PF04828.14 KFY01241.1 - 6.3e-10 39.3 0.3 0.00021 21.6 0.1 2.8 2 0 0 2 2 2 2 Glutathione-dependent formaldehyde-activating enzyme zf-NADH-PPase PF09297.11 KFY01241.1 - 0.0013 18.3 1.2 1.7 8.4 0.1 2.6 2 0 0 2 2 2 2 NADH pyrophosphatase zinc ribbon domain zinc_ribbon_2 PF13240.6 KFY01241.1 - 0.02 14.6 4.3 0.17 11.6 0.5 2.8 2 0 0 2 2 2 0 zinc-ribbon domain zf-ribbon_3 PF13248.6 KFY01241.1 - 0.1 12.0 3.6 0.58 9.7 0.3 3.1 2 0 0 2 2 2 0 zinc-ribbon domain Nudix_N_2 PF14803.6 KFY01241.1 - 0.13 12.2 4.3 2 8.4 0.2 3.0 3 0 0 3 3 3 0 Nudix N-terminal DUF1186 PF06685.11 KFY01241.1 - 0.23 10.8 0.0 0.4 10.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1186) NOB1_Zn_bind PF08772.11 KFY01241.1 - 1.3 9.2 4.6 3.2 8.0 0.3 2.6 2 0 0 2 2 2 0 Nin one binding (NOB1) Zn-ribbon like Glyco_hydro_92 PF07971.12 KFY01242.1 - 8.1e-143 476.7 0.2 1e-142 476.4 0.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 Glyco_hydro_92N PF17678.1 KFY01242.1 - 3e-69 233.6 2.3 3.4e-69 233.3 1.0 1.8 2 0 0 2 2 2 1 Glycosyl hydrolase family 92 N-terminal domain AA_permease_2 PF13520.6 KFY01243.1 - 1.8e-84 284.1 42.5 2.3e-84 283.7 42.5 1.1 1 0 0 1 1 1 1 Amino acid permease DUF1453 PF07301.11 KFY01243.1 - 0.039 14.0 0.4 0.039 14.0 0.4 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1453) MFS_1 PF07690.16 KFY01244.1 - 5.7e-18 64.9 28.6 5.7e-18 64.9 28.6 2.0 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KFY01244.1 - 1.2e-10 40.9 17.4 4e-10 39.1 17.4 1.7 1 1 0 1 1 1 1 Sugar (and other) transporter LRR_4 PF12799.7 KFY01245.1 - 1.9e-26 91.7 30.2 6.6e-05 23.2 0.2 8.2 7 1 1 8 8 8 7 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 KFY01245.1 - 2e-25 88.3 31.3 8.4e-07 28.7 3.5 7.1 5 2 1 6 6 6 5 Leucine rich repeat LRR_9 PF14580.6 KFY01245.1 - 3.9e-09 36.3 13.2 0.00016 21.2 0.6 4.6 1 1 3 5 5 5 4 Leucine-rich repeat LRR_1 PF00560.33 KFY01245.1 - 0.022 15.2 32.5 4 8.3 0.4 10.4 10 3 1 11 11 11 0 Leucine Rich Repeat Tubulin PF00091.25 KFY01246.1 - 4.9e-65 219.4 0.0 6.6e-65 219.0 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 KFY01246.1 - 1.9e-46 157.3 0.0 3e-46 156.7 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 KFY01246.1 - 0.0012 18.6 0.0 0.0026 17.5 0.0 1.5 1 0 0 1 1 1 1 Tubulin domain Tim17 PF02466.19 KFY01247.1 - 1.2e-11 45.0 2.2 1.8e-11 44.4 2.2 1.2 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family DUF5518 PF17647.1 KFY01247.1 - 0.0023 18.0 2.0 0.15 12.3 0.8 2.3 1 1 1 2 2 2 2 Family of unknown function (DUF5518) EpuA PF11772.8 KFY01247.1 - 0.039 13.6 0.4 0.21 11.3 0.0 2.2 2 0 0 2 2 2 0 DNA-directed RNA polymerase subunit beta Brix PF04427.18 KFY01248.1 - 2.1e-43 148.7 0.1 2.9e-43 148.2 0.1 1.2 1 0 0 1 1 1 1 Brix domain Sugar_tr PF00083.24 KFY01250.1 - 7.8e-81 272.2 25.5 9.5e-81 271.9 25.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KFY01250.1 - 8.3e-33 113.8 27.3 2.3e-28 99.1 20.6 2.3 1 1 2 3 3 3 2 Major Facilitator Superfamily MFS_2 PF13347.6 KFY01250.1 - 3.7e-06 25.8 5.2 3.7e-06 25.8 5.2 2.5 2 1 0 2 2 2 1 MFS/sugar transport protein TRI12 PF06609.13 KFY01250.1 - 6.2e-05 21.6 2.5 0.0001 20.9 2.5 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_4 PF06779.14 KFY01250.1 - 0.01 15.2 11.8 0.017 14.4 7.8 2.6 2 1 1 3 3 3 2 Uncharacterised MFS-type transporter YbfB Hydrophobin_2 PF06766.11 KFY01251.1 - 0.0013 18.7 3.3 0.0022 17.9 3.3 1.4 1 1 0 1 1 1 1 Fungal hydrophobin EphA2_TM PF14575.6 KFY01252.1 - 0.047 14.6 0.0 0.11 13.4 0.0 1.6 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain IgG_binding_B PF01378.17 KFY01252.1 - 0.17 11.9 0.0 7.4 6.7 0.0 2.3 2 0 0 2 2 2 0 B domain RgpF PF05045.12 KFY01253.1 - 0.0075 15.1 0.2 0.016 14.0 0.0 1.6 2 0 0 2 2 2 1 Rhamnan synthesis protein F RNA_pol_I_A49 PF06870.12 KFY01254.1 - 3.4e-93 312.6 1.5 4.1e-93 312.3 1.5 1.1 1 0 0 1 1 1 1 A49-like RNA polymerase I associated factor HDOD PF08668.12 KFY01254.1 - 0.094 12.2 0.1 0.22 11.0 0.0 1.5 2 0 0 2 2 2 0 HDOD domain Ribosomal_L41 PF05162.13 KFY01255.1 - 1.5e-08 34.5 26.5 2.8e-08 33.7 26.5 1.4 1 0 0 1 1 1 1 Ribosomal protein L41 SAC3_GANP PF03399.16 KFY01256.1 - 6.4e-99 331.0 0.3 1.4e-98 329.9 0.3 1.6 1 0 0 1 1 1 1 SAC3/GANP family Pkinase PF00069.25 KFY01256.1 - 3e-58 197.3 0.1 1.1e-57 195.5 0.0 2.0 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFY01256.1 - 2.2e-26 92.7 0.0 4.4e-26 91.7 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.26 KFY01256.1 - 1.8e-08 34.6 0.0 4.3e-08 33.4 0.0 1.6 1 0 0 1 1 1 1 FHA domain Kinase-like PF14531.6 KFY01256.1 - 8.5e-06 25.3 0.0 2.7e-05 23.6 0.0 1.7 1 1 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 KFY01256.1 - 0.00035 19.5 0.0 0.00035 19.5 0.0 2.4 2 0 0 2 2 2 1 Fungal protein kinase Kdo PF06293.14 KFY01256.1 - 0.00084 18.8 0.0 0.0019 17.6 0.0 1.6 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family CSN8_PSD8_EIF3K PF10075.9 KFY01256.1 - 0.0075 16.3 0.1 0.017 15.1 0.1 1.5 1 0 0 1 1 1 1 CSN8/PSMD8/EIF3K family DKCLD PF08068.12 KFY01257.1 - 3.7e-33 113.4 0.3 1e-31 108.8 0.3 2.4 2 0 0 2 2 2 1 DKCLD (NUC011) domain TruB_N PF01509.18 KFY01257.1 - 2.3e-23 83.2 0.2 2.8e-20 73.2 0.2 3.5 1 1 0 1 1 1 1 TruB family pseudouridylate synthase (N terminal domain) TruB_C_2 PF16198.5 KFY01257.1 - 1.6e-22 79.4 1.2 3e-22 78.5 1.2 1.5 1 0 0 1 1 1 1 tRNA pseudouridylate synthase B C-terminal domain PUA PF01472.20 KFY01257.1 - 9.8e-22 76.7 1.3 2e-21 75.7 1.3 1.6 1 0 0 1 1 1 1 PUA domain UPF0113 PF03657.13 KFY01257.1 - 0.0018 18.5 0.0 0.0047 17.2 0.0 1.7 1 0 0 1 1 1 1 UPF0113 PUA domain AP3D1 PF06375.11 KFY01257.1 - 0.45 10.7 18.4 0.76 10.0 18.4 1.3 1 0 0 1 1 1 0 AP-3 complex subunit delta-1 DUF4407 PF14362.6 KFY01257.1 - 8.6 5.6 5.7 15 4.8 5.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) LtrA PF06772.11 KFY01259.1 - 5.3e-32 111.4 27.2 7.8e-32 110.9 27.2 1.2 1 0 0 1 1 1 1 Bacterial low temperature requirement A protein (LtrA) Bac_rhamnosid6H PF17389.2 KFY01259.1 - 6.9e-11 42.0 0.2 1.4e-10 41.0 0.2 1.4 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain Bac_rhamnosid_C PF17390.2 KFY01259.1 - 0.016 15.0 0.1 0.034 13.9 0.1 1.6 1 0 0 1 1 1 0 Bacterial alpha-L-rhamnosidase C-terminal domain GDE_C PF06202.14 KFY01259.1 - 0.022 13.7 0.1 0.035 13.0 0.1 1.2 1 0 0 1 1 1 0 Amylo-alpha-1,6-glucosidase Trehalase PF01204.18 KFY01259.1 - 0.045 12.6 0.1 0.069 12.0 0.1 1.1 1 0 0 1 1 1 0 Trehalase Amidase PF01425.21 KFY01262.1 - 2.4e-76 257.5 0.1 2.4e-74 250.9 0.1 2.1 1 1 0 1 1 1 1 Amidase zf-PARP PF00645.18 KFY01263.1 - 4.3e-20 72.4 2.2 5.4e-20 72.0 0.1 2.4 2 0 0 2 2 2 1 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region Dynactin_p62 PF05502.13 KFY01264.1 - 4.2e-169 563.3 0.5 5.9e-169 562.8 0.5 1.1 1 0 0 1 1 1 1 Dynactin p62 family Microcephalin PF12258.8 KFY01264.1 - 0.0025 17.1 3.4 0.0047 16.2 3.4 1.4 1 0 0 1 1 1 1 Microcephalin protein Lipase_GDSL PF00657.22 KFY01265.1 - 7.4e-10 39.1 0.1 1.7e-09 37.9 0.1 1.7 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.6 KFY01265.1 - 9.4e-09 35.9 5.4 2.8e-08 34.3 5.4 1.9 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family CE2_N PF17996.1 KFY01265.1 - 0.024 14.6 0.0 0.051 13.6 0.0 1.5 1 0 0 1 1 1 0 Carbohydrate esterase 2 N-terminal ADH_N PF08240.12 KFY01266.1 - 9.8e-26 89.8 2.8 1.5e-25 89.2 2.8 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KFY01266.1 - 1.5e-11 44.4 0.0 2.7e-11 43.5 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 KFY01266.1 - 0.0049 16.2 0.1 0.0084 15.5 0.1 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ADH_zinc_N_2 PF13602.6 KFY01266.1 - 0.09 13.8 0.0 0.14 13.2 0.0 1.3 1 0 0 1 1 1 0 Zinc-binding dehydrogenase DUF829 PF05705.14 KFY01267.1 - 3.2e-49 168.0 0.1 3.7e-49 167.8 0.1 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF829) ATP_transf PF09830.9 KFY01268.1 - 1.4e-18 66.8 0.0 2.5e-18 66.0 0.0 1.4 1 0 0 1 1 1 1 ATP adenylyltransferase GLEYA PF10528.9 KFY01269.1 - 5e-38 129.4 0.2 2.1e-20 73.0 0.0 2.4 2 0 0 2 2 2 2 GLEYA domain PA14 PF07691.12 KFY01269.1 - 4.9e-09 36.2 0.3 8e-05 22.5 0.1 2.3 2 0 0 2 2 2 2 PA14 domain PAN_1 PF00024.26 KFY01269.1 - 7.6e-06 25.8 0.4 7.6e-06 25.8 0.4 1.8 2 0 0 2 2 2 1 PAN domain PAN_3 PF08277.12 KFY01269.1 - 0.011 15.5 4.5 0.029 14.2 4.5 1.7 1 0 0 1 1 1 0 PAN-like domain PLL PF18587.1 KFY01269.1 - 0.025 14.7 0.2 8.6 6.5 0.0 2.4 2 0 0 2 2 2 0 PTX/LNS-Like (PLL) domain PAN_4 PF14295.6 KFY01269.1 - 0.29 11.1 5.9 1.3 9.0 5.9 2.2 1 0 0 1 1 1 0 PAN domain MFS_1 PF07690.16 KFY01270.1 - 2.2e-14 53.2 18.3 5.3e-14 51.9 18.3 1.6 1 0 0 1 1 1 1 Major Facilitator Superfamily Oxidored_molyb PF00174.19 KFY01271.1 - 2.5e-44 150.9 0.0 4.9e-44 150.0 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain TauD PF02668.16 KFY01271.1 - 9.4e-44 150.2 0.2 1.5e-43 149.6 0.2 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Mo-co_dimer PF03404.16 KFY01271.1 - 1.6e-19 70.3 4.1 4.2e-19 68.9 4.1 1.7 1 0 0 1 1 1 1 Mo-co oxidoreductase dimerisation domain WD40 PF00400.32 KFY01272.1 - 8.4e-25 86.6 20.6 1.1e-05 26.0 0.0 6.7 6 0 0 6 6 6 6 WD domain, G-beta repeat F-box-like PF12937.7 KFY01272.1 - 2.7e-10 40.0 0.0 5.1e-10 39.1 0.0 1.5 1 0 0 1 1 1 1 F-box-like Nup160 PF11715.8 KFY01272.1 - 6.1e-07 28.5 2.4 0.013 14.2 0.1 3.6 2 2 2 4 4 4 3 Nucleoporin Nup120/160 F-box PF00646.33 KFY01272.1 - 2.6e-05 24.0 0.0 6e-05 22.8 0.0 1.6 1 0 0 1 1 1 1 F-box domain ANAPC4_WD40 PF12894.7 KFY01272.1 - 4.4e-05 23.7 0.1 0.78 10.1 0.0 4.5 3 1 2 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain F-box_4 PF15966.5 KFY01272.1 - 0.11 12.3 0.0 0.25 11.2 0.0 1.5 1 0 0 1 1 1 0 F-box Elongin_A PF06881.11 KFY01272.1 - 0.13 12.8 0.0 0.72 10.4 0.0 2.1 2 0 0 2 2 2 0 RNA polymerase II transcription factor SIII (Elongin) subunit A Pfk_N PF18468.1 KFY01275.1 - 0.15 12.5 0.0 0.29 11.6 0.0 1.4 1 0 0 1 1 1 0 Phosphofructokinase N-terminal domain yeast hDGE_amylase PF14701.6 KFY01276.1 - 1.2e-179 598.0 0.0 1.5e-179 597.7 0.0 1.1 1 0 0 1 1 1 1 Glycogen debranching enzyme, glucanotransferase domain GDE_C PF06202.14 KFY01276.1 - 5.8e-118 394.2 0.0 8.7e-118 393.6 0.0 1.2 1 0 0 1 1 1 1 Amylo-alpha-1,6-glucosidase hGDE_central PF14702.6 KFY01276.1 - 1.8e-86 289.9 0.0 3.4e-86 289.0 0.0 1.5 1 0 0 1 1 1 1 Central domain of human glycogen debranching enzyme hGDE_N PF14699.6 KFY01276.1 - 2.4e-28 98.1 0.0 5.5e-28 96.9 0.0 1.7 1 0 0 1 1 1 1 N-terminal domain from the human glycogen debranching enzyme Alpha-amylase PF00128.24 KFY01276.1 - 0.00058 19.5 0.0 0.0019 17.8 0.0 1.8 2 0 0 2 2 2 1 Alpha amylase, catalytic domain YCII PF03795.14 KFY01276.1 - 0.13 12.7 0.0 0.72 10.3 0.0 2.2 2 0 0 2 2 2 0 YCII-related domain DAHP_synth_1 PF00793.20 KFY01277.1 - 2.1e-102 341.7 0.0 2.9e-102 341.2 0.0 1.1 1 0 0 1 1 1 1 DAHP synthetase I family Autophagy_act_C PF03987.15 KFY01278.1 - 3.2e-13 50.1 0.7 5.3e-13 49.3 0.7 1.4 1 0 0 1 1 1 1 Autophagocytosis associated protein, active-site domain Cytochrom_C1 PF02167.15 KFY01279.1 - 4.9e-94 314.1 0.0 6.4e-94 313.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome C1 family Cytochrome_CBB3 PF13442.6 KFY01279.1 - 0.018 15.4 0.0 0.038 14.3 0.0 1.6 1 0 0 1 1 1 0 Cytochrome C oxidase, cbb3-type, subunit III DUF1515 PF07439.11 KFY01279.1 - 0.14 12.2 0.3 0.3 11.2 0.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1515) HhH-GPD PF00730.25 KFY01280.1 - 0.00098 19.6 0.0 0.003 18.0 0.0 1.8 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein MFS_1 PF07690.16 KFY01308.1 - 5.2e-42 144.0 54.2 6.6e-41 140.4 52.2 2.6 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 KFY01308.1 - 9.3e-12 44.2 21.7 1.3e-11 43.6 21.7 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 KFY01308.1 - 3.1e-11 42.8 10.9 3.1e-11 42.8 10.9 2.3 2 0 0 2 2 2 2 Sugar (and other) transporter Lamprin PF06403.11 KFY01309.1 - 0.34 10.9 0.9 0.47 10.4 0.9 1.1 1 0 0 1 1 1 0 Lamprin Chorion_1 PF01723.16 KFY01309.1 - 0.79 9.7 3.9 1.2 9.1 3.9 1.2 1 0 0 1 1 1 0 Chorion protein DUF2151 PF10221.9 KFY01310.1 - 0.12 11.0 7.4 0.13 10.8 7.4 1.0 1 0 0 1 1 1 0 Cell cycle and development regulator Nop14 PF04147.12 KFY01310.1 - 0.78 7.9 28.2 0.85 7.8 28.2 1.0 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.12 KFY01310.1 - 1.1 8.7 29.2 1.1 8.6 29.2 1.1 1 0 0 1 1 1 0 SDA1 BUD22 PF09073.10 KFY01310.1 - 1.7 7.9 25.5 2 7.7 25.5 1.0 1 0 0 1 1 1 0 BUD22 Abhydrolase_6 PF12697.7 KFY01311.1 - 2.2e-13 51.3 3.4 3.1e-13 50.9 3.4 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KFY01311.1 - 6.5e-10 38.7 0.1 1.1e-09 37.9 0.1 1.4 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KFY01311.1 - 1.4e-05 24.9 0.2 1.9e-05 24.4 0.2 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_3 PF07859.13 KFY01311.1 - 0.0026 17.7 0.0 0.0036 17.2 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold AXE1 PF05448.12 KFY01311.1 - 0.21 10.2 0.1 2.2 6.9 0.1 2.2 1 1 0 1 1 1 0 Acetyl xylan esterase (AXE1) BLOC1_2 PF10046.9 KFY01313.1 - 0.015 15.6 0.9 0.018 15.4 0.9 1.2 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF3450 PF11932.8 KFY01313.1 - 0.016 14.5 1.1 0.019 14.2 1.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) Ank_4 PF13637.6 KFY01314.1 - 3.2e-09 37.1 0.1 1.3e-05 25.6 0.0 2.1 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 KFY01314.1 - 1.8e-08 34.5 0.0 3.8e-08 33.5 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 KFY01314.1 - 5.5e-07 30.1 0.1 9.8e-07 29.3 0.1 1.4 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KFY01314.1 - 0.0013 19.1 0.0 0.056 14.0 0.0 2.9 3 0 0 3 3 3 1 Ankyrin repeat Ank PF00023.30 KFY01314.1 - 0.0016 18.8 0.1 1.3 9.6 0.0 3.1 3 0 0 3 3 3 2 Ankyrin repeat Ank_2 PF12796.7 KFY01316.1 - 5.5e-23 81.4 0.9 1.3e-11 44.9 0.0 2.8 3 1 0 3 3 3 2 Ankyrin repeats (3 copies) Ank PF00023.30 KFY01316.1 - 3.9e-16 58.7 1.5 0.00055 20.3 0.0 5.2 4 1 1 5 5 5 3 Ankyrin repeat Ank_4 PF13637.6 KFY01316.1 - 9.6e-14 51.6 0.1 2.9e-08 34.1 0.0 3.8 2 1 2 4 4 4 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFY01316.1 - 2.1e-13 49.1 0.1 0.00082 19.6 0.0 5.3 5 0 0 5 5 5 3 Ankyrin repeat Ank_5 PF13857.6 KFY01316.1 - 5.2e-10 39.4 1.4 0.00035 20.8 0.1 4.3 2 2 2 4 4 4 4 Ankyrin repeats (many copies) F-box-like PF12937.7 KFY01316.1 - 0.0068 16.3 0.6 0.035 14.0 0.1 2.4 3 0 0 3 3 3 1 F-box-like Hydant_A_N PF05378.13 KFY01316.1 - 0.036 13.8 0.0 0.61 9.8 0.0 2.2 1 1 0 2 2 2 0 Hydantoinase/oxoprolinase N-terminal region DUF4147 PF13660.6 KFY01316.1 - 0.12 11.9 0.1 2.2 7.8 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4147) Arginase PF00491.21 KFY01318.1 - 2.1e-43 148.8 0.1 2.4e-43 148.7 0.1 1.0 1 0 0 1 1 1 1 Arginase family Fungal_trans_2 PF11951.8 KFY01319.1 - 9.3e-31 107.0 1.1 1.1e-30 106.7 1.1 1.0 1 0 0 1 1 1 1 Fungal specific transcription factor domain DHNA PF04038.12 KFY01319.1 - 0.17 12.4 0.0 0.35 11.4 0.0 1.4 1 0 0 1 1 1 0 Dihydroneopterin aldolase Acatn PF13000.7 KFY01320.1 - 1.7e-145 485.7 30.0 3.7e-82 276.6 7.8 3.7 2 1 2 4 4 4 3 Acetyl-coenzyme A transporter 1 MFS_1 PF07690.16 KFY01320.1 - 1.4e-26 93.3 61.4 2.8e-21 75.8 20.7 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 KFY01320.1 - 0.0018 17.2 8.2 0.0018 17.2 8.2 2.5 3 0 0 3 3 3 2 MFS_1 like family DUF3723 PF12520.8 KFY01351.1 - 2.4e-44 151.9 0.0 3e-44 151.6 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3723) DUF3723 PF12520.8 KFY01352.1 - 4.2e-20 71.9 0.5 1.4e-18 66.9 0.4 2.0 1 1 1 2 2 2 2 Protein of unknown function (DUF3723) p450 PF00067.22 KFY01354.1 - 8.7e-23 80.8 0.0 6.8e-22 77.8 0.0 1.9 1 1 0 1 1 1 1 Cytochrome P450 Lactamase_B_3 PF13483.6 KFY01355.1 - 4.5e-06 26.7 0.0 1.1e-05 25.4 0.0 1.6 2 0 0 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B_2 PF12706.7 KFY01355.1 - 0.00027 20.5 0.1 0.00098 18.7 0.1 1.9 1 1 0 1 1 1 1 Beta-lactamase superfamily domain DUF3723 PF12520.8 KFY01356.1 - 3.1e-91 306.6 1.0 1.1e-90 304.8 0.3 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF3723) HTH_3 PF01381.22 KFY01356.1 - 0.077 13.1 1.8 0.87 9.7 0.1 3.5 3 0 0 3 3 3 0 Helix-turn-helix DUF4442 PF14539.6 KFY01358.1 - 0.1 12.7 0.1 0.21 11.7 0.1 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4442) Saf_2TM PF18303.1 KFY01358.1 - 0.29 10.7 1.8 1.9 8.0 0.7 2.3 2 0 0 2 2 2 0 SAVED-fused 2TM effector domain DUF3593 PF12159.8 KFY01358.1 - 0.44 10.6 4.7 1 9.5 0.1 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF3593) DUF2975 PF11188.8 KFY01358.1 - 1.5 8.8 10.5 0.063 13.2 2.0 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF2975) Cob_adeno_trans PF01923.18 KFY01360.1 - 0.091 12.9 0.6 0.14 12.3 0.6 1.3 1 0 0 1 1 1 0 Cobalamin adenosyltransferase TraN PF06986.11 KFY01361.1 - 0.029 14.1 1.4 0.039 13.6 1.4 1.1 1 0 0 1 1 1 0 Type-1V conjugative transfer system mating pair stabilisation ATG2_CAD PF13329.6 KFY01361.1 - 0.14 11.9 0.4 0.2 11.4 0.4 1.2 1 0 0 1 1 1 0 Autophagy-related protein 2 CAD motif Trypan_PARP PF05887.11 KFY01363.1 - 0.0098 15.9 6.0 0.013 15.5 6.0 1.2 1 0 0 1 1 1 1 Procyclic acidic repetitive protein (PARP) Condensation PF00668.20 KFY01366.1 - 1.1e-25 90.3 0.0 7.6e-15 54.5 0.0 2.1 2 0 0 2 2 2 2 Condensation domain PP-binding PF00550.25 KFY01366.1 - 5.4e-09 36.3 0.1 1.6e-08 34.8 0.1 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site RNA_pol PF00940.19 KFY01367.1 - 1.8e-187 623.3 0.3 2.8e-187 622.6 0.3 1.3 1 0 0 1 1 1 1 DNA-dependent RNA polymerase RPOL_N PF14700.6 KFY01367.1 - 3.1e-102 342.4 5.0 3.1e-102 342.4 5.0 2.2 2 0 0 2 2 2 1 DNA-directed RNA polymerase N-terminal Ribosomal_60s PF00428.19 KFY01367.1 - 8.7 7.0 12.4 7.5 7.2 9.8 2.3 2 0 0 2 2 2 0 60s Acidic ribosomal protein RsfS PF02410.15 KFY01368.1 - 4.6e-14 52.7 0.0 1.3e-13 51.2 0.0 1.8 2 0 0 2 2 2 1 Ribosomal silencing factor during starvation Acetyltransf_1 PF00583.25 KFY01369.1 - 1.4e-18 67.2 0.0 1.8e-18 66.9 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KFY01369.1 - 1e-13 51.3 0.0 1.5e-13 50.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KFY01369.1 - 7.3e-12 45.6 0.0 1.1e-11 45.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KFY01369.1 - 1.4e-06 28.2 0.0 2.1e-06 27.6 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_3 PF13302.7 KFY01369.1 - 4.9e-05 24.0 0.0 5.9e-05 23.8 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 KFY01369.1 - 5.4e-05 23.2 0.0 8.9e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_4 PF13420.7 KFY01369.1 - 0.00078 19.6 0.0 0.001 19.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_18 PF18014.1 KFY01369.1 - 0.0076 16.1 0.0 3.7 7.4 0.0 2.3 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain DUF3636 PF12331.8 KFY01370.1 - 2.1e-49 167.2 0.0 4.4e-49 166.1 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3636) CTP_transf_1 PF01148.20 KFY01371.1 - 2.3e-81 273.5 25.0 2.9e-81 273.1 25.0 1.1 1 0 0 1 1 1 1 Cytidylyltransferase family Thiolase_N PF00108.23 KFY01372.1 - 3.4e-70 236.4 0.9 4.6e-70 235.9 0.9 1.2 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 KFY01372.1 - 7e-40 135.5 0.2 1.6e-39 134.4 0.2 1.6 1 0 0 1 1 1 1 Thiolase, C-terminal domain ACP_syn_III PF08545.10 KFY01372.1 - 0.0011 18.8 0.4 0.36 10.7 0.3 2.5 2 0 0 2 2 2 2 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III ACP_syn_III_C PF08541.10 KFY01372.1 - 0.017 15.3 0.0 0.05 13.8 0.0 1.9 1 0 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal ketoacyl-synt PF00109.26 KFY01372.1 - 0.084 12.4 2.6 0.16 11.5 1.6 1.9 2 0 0 2 2 2 0 Beta-ketoacyl synthase, N-terminal domain Sulfate_transp PF00916.20 KFY01373.1 - 2e-83 280.2 8.4 2.7e-83 279.8 8.4 1.1 1 0 0 1 1 1 1 Sulfate permease family STAS PF01740.21 KFY01373.1 - 1.2e-14 54.0 0.0 2.2e-14 53.1 0.0 1.5 1 0 0 1 1 1 1 STAS domain STAS_2 PF13466.6 KFY01373.1 - 0.084 13.2 0.0 0.2 12.0 0.0 1.7 1 0 0 1 1 1 0 STAS domain MFS_MOT1 PF16983.5 KFY01373.1 - 6.3 7.2 16.7 0.043 14.2 3.6 2.9 2 1 0 2 2 2 0 Molybdate transporter of MFS superfamily Adaptin_N PF01602.20 KFY01374.1 - 2.4e-125 419.1 7.7 3e-125 418.7 7.7 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 KFY01374.1 - 1.8e-55 187.4 0.1 1.8e-55 187.4 0.1 3.8 3 1 1 4 4 4 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 KFY01374.1 - 4.7e-15 55.7 4.4 9.4e-05 22.7 0.0 5.1 4 1 1 5 5 5 4 HEAT repeats HEAT PF02985.22 KFY01374.1 - 8.8e-12 44.2 2.3 0.00063 19.8 0.0 5.6 6 0 0 6 6 6 3 HEAT repeat HEAT_EZ PF13513.6 KFY01374.1 - 8.4e-07 29.4 3.8 0.64 10.6 0.1 6.2 6 0 0 6 6 6 2 HEAT-like repeat Arm PF00514.23 KFY01374.1 - 0.00032 20.6 0.3 4 7.6 0.0 4.7 4 0 0 4 4 4 1 Armadillo/beta-catenin-like repeat Atx10homo_assoc PF09759.9 KFY01374.1 - 0.0011 19.0 0.1 11 6.1 0.0 4.7 4 0 0 4 4 4 1 Spinocerebellar ataxia type 10 protein domain CLASP_N PF12348.8 KFY01374.1 - 0.0029 17.2 2.4 1.8 8.1 0.0 3.3 3 0 0 3 3 3 2 CLASP N terminal RTP1_C1 PF10363.9 KFY01374.1 - 0.043 14.0 0.8 5 7.3 0.0 3.5 2 1 1 3 3 3 0 Required for nuclear transport of RNA pol II C-terminus 1 TIP120 PF08623.10 KFY01374.1 - 0.25 11.1 3.8 4.2 7.1 0.2 3.2 4 1 1 5 5 5 0 TATA-binding protein interacting (TIP20) DUF1077 PF06417.12 KFY01375.1 - 3.2e-49 165.9 2.4 3.8e-49 165.6 2.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1077) EMP70 PF02990.16 KFY01375.1 - 0.056 12.1 0.2 0.062 12.0 0.2 1.0 1 0 0 1 1 1 0 Endomembrane protein 70 ADH_zinc_N PF00107.26 KFY01376.1 - 5.9e-20 71.6 0.4 9.2e-20 70.9 0.4 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KFY01376.1 - 1e-07 33.0 0.0 1.8e-07 32.3 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase GYF PF02213.16 KFY01377.1 - 1.8e-16 59.5 0.6 3.9e-16 58.4 0.6 1.6 1 0 0 1 1 1 1 GYF domain Host_attach PF10116.9 KFY01378.1 - 0.65 10.6 4.3 1.2 9.7 4.3 1.4 1 0 0 1 1 1 0 Protein required for attachment to host cells Rick_17kDa_Anti PF05433.15 KFY01379.1 - 8.8e-05 22.3 29.7 0.00045 20.0 18.2 2.4 2 1 1 3 3 3 2 Glycine zipper 2TM domain DUF755 PF05501.11 KFY01379.1 - 0.64 10.3 11.2 0.9 9.8 11.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF755) HlyIII PF03006.20 KFY01380.1 - 6.6e-59 199.3 17.7 8.6e-59 199.0 17.7 1.1 1 0 0 1 1 1 1 Haemolysin-III related BA14K PF07886.11 KFY01380.1 - 0.053 13.4 0.9 0.11 12.4 0.9 1.5 1 0 0 1 1 1 0 BA14K-like protein Phage_holin_2_1 PF04971.12 KFY01380.1 - 0.16 12.0 3.7 0.59 10.2 0.3 2.9 2 1 1 3 3 3 0 Bacteriophage P21 holin S MerC PF03203.14 KFY01380.1 - 0.74 10.3 15.4 1.9 9.0 1.5 3.6 3 1 0 4 4 4 0 MerC mercury resistance protein zf-C2HC5 PF06221.13 KFY01381.1 - 3.7e-21 74.9 4.9 5.8e-21 74.2 4.9 1.3 1 0 0 1 1 1 1 Putative zinc finger motif, C2HC5-type Aminotran_5 PF00266.19 KFY01382.1 - 5.4e-20 71.7 0.0 7.3e-20 71.2 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.21 KFY01382.1 - 0.00056 19.2 0.0 0.00083 18.6 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.17 KFY01382.1 - 0.19 11.0 0.2 1.1 8.5 0.2 1.9 1 1 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family SIS PF01380.22 KFY01384.1 - 1.2e-54 183.7 0.0 2.7e-29 101.7 0.0 2.3 2 0 0 2 2 2 2 SIS domain GATase_6 PF13522.6 KFY01384.1 - 5.7e-18 65.4 0.0 1.1e-17 64.4 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.6 KFY01384.1 - 2e-11 43.9 0.0 4.7e-11 42.7 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_4 PF13230.6 KFY01384.1 - 0.002 17.1 0.0 0.0033 16.4 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferases class-II AAA PF00004.29 KFY01385.1 - 2.8e-42 144.3 0.0 4.8e-42 143.5 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_ID_OB PF16450.5 KFY01385.1 - 7.1e-13 48.3 0.2 1.1e-11 44.6 0.0 2.3 2 0 0 2 2 2 1 Proteasomal ATPase OB C-terminal domain AAA_lid_3 PF17862.1 KFY01385.1 - 1.1e-10 41.1 0.1 2.7e-10 39.9 0.1 1.7 2 0 0 2 2 1 1 AAA+ lid domain AAA_16 PF13191.6 KFY01385.1 - 1.1e-06 29.2 0.0 0.00047 20.6 0.1 2.8 2 1 1 3 3 3 1 AAA ATPase domain AAA_5 PF07728.14 KFY01385.1 - 3.5e-06 27.1 0.2 8.6e-05 22.6 0.1 2.8 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 KFY01385.1 - 8.9e-06 25.9 0.0 2.7e-05 24.4 0.0 1.8 2 0 0 2 2 1 1 AAA domain (Cdc48 subfamily) RuvB_N PF05496.12 KFY01385.1 - 1.2e-05 25.1 0.0 2.4e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 KFY01385.1 - 0.0004 20.7 0.1 0.0066 16.7 0.1 2.4 1 1 0 1 1 1 1 AAA domain DUF815 PF05673.13 KFY01385.1 - 0.00099 18.3 0.0 0.0023 17.1 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_18 PF13238.6 KFY01385.1 - 0.0019 18.8 0.1 0.0085 16.6 0.0 2.2 2 1 0 2 2 1 1 AAA domain AAA_7 PF12775.7 KFY01385.1 - 0.0021 17.6 0.0 0.0041 16.6 0.0 1.5 1 0 0 1 1 1 1 P-loop containing dynein motor region Prot_ATP_OB_N PF17758.1 KFY01385.1 - 0.003 17.2 0.0 0.0083 15.8 0.0 1.7 1 0 0 1 1 1 1 Proteasomal ATPase OB N-terminal domain TsaE PF02367.17 KFY01385.1 - 0.0032 17.5 0.0 0.0062 16.5 0.0 1.4 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE TIP49 PF06068.13 KFY01385.1 - 0.0056 15.9 0.0 0.011 15.0 0.0 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain Mg_chelatase PF01078.21 KFY01385.1 - 0.0061 16.0 0.0 0.012 15.1 0.0 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_33 PF13671.6 KFY01385.1 - 0.011 15.9 0.0 0.028 14.6 0.0 1.8 2 0 0 2 2 1 0 AAA domain IstB_IS21 PF01695.17 KFY01385.1 - 0.012 15.4 0.0 0.025 14.3 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein RNA_helicase PF00910.22 KFY01385.1 - 0.012 15.9 0.0 0.024 15.0 0.0 1.5 1 0 0 1 1 1 0 RNA helicase Sigma54_activat PF00158.26 KFY01385.1 - 0.015 15.0 0.0 0.049 13.3 0.0 2.0 1 1 0 1 1 1 0 Sigma-54 interaction domain AAA_14 PF13173.6 KFY01385.1 - 0.018 15.0 0.0 0.039 14.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 KFY01385.1 - 0.028 14.1 0.0 0.078 12.7 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_3 PF07726.11 KFY01385.1 - 0.038 13.8 0.0 0.089 12.7 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 KFY01385.1 - 0.039 13.7 0.1 0.13 11.9 0.0 1.8 2 0 0 2 2 2 0 AAA domain ATPase PF06745.13 KFY01385.1 - 0.042 13.2 0.1 0.15 11.4 0.0 1.9 2 0 0 2 2 2 0 KaiC NACHT PF05729.12 KFY01385.1 - 0.055 13.4 0.1 0.14 12.1 0.0 1.7 2 0 0 2 2 2 0 NACHT domain Parvo_NS1 PF01057.17 KFY01385.1 - 0.1 11.7 0.0 0.17 11.0 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 PhoH PF02562.16 KFY01385.1 - 0.11 11.9 0.0 0.19 11.1 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein AAA_28 PF13521.6 KFY01385.1 - 0.12 12.7 0.0 0.25 11.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 KFY01385.1 - 0.15 11.6 0.0 0.37 10.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.6 KFY01385.1 - 0.5 10.1 0.0 0.5 10.1 0.0 2.0 3 0 0 3 3 2 0 AAA domain Enolase_C PF00113.22 KFY01386.1 - 3.9e-151 502.3 0.0 5.2e-151 501.9 0.0 1.2 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.16 KFY01386.1 - 2.2e-58 196.1 0.2 3.6e-58 195.4 0.2 1.4 1 0 0 1 1 1 1 Enolase, N-terminal domain MR_MLE_C PF13378.6 KFY01386.1 - 6.9e-06 25.8 0.0 1.2e-05 25.0 0.0 1.3 1 0 0 1 1 1 1 Enolase C-terminal domain-like MAAL_C PF07476.11 KFY01386.1 - 0.028 13.6 0.3 4.4 6.4 0.1 3.0 3 0 0 3 3 3 0 Methylaspartate ammonia-lyase C-terminus DUF4733 PF15878.5 KFY01386.1 - 0.11 12.9 0.1 0.2 12.1 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4733) Glyco_hydro_61 PF03443.14 KFY01390.1 - 1.8e-59 201.1 0.4 2.3e-59 200.8 0.4 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 NPCBM_assoc PF10633.9 KFY01390.1 - 0.029 14.6 0.0 0.2 12.0 0.0 2.3 2 0 0 2 2 2 0 NPCBM-associated, NEW3 domain of alpha-galactosidase Glyco_hydro_61 PF03443.14 KFY01391.1 - 9.9e-49 166.1 0.0 1.2e-48 165.8 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Lipase_GDSL_2 PF13472.6 KFY01393.1 - 1.7e-07 31.8 3.8 3.2e-07 30.9 3.8 1.6 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 KFY01393.1 - 4e-05 23.7 0.0 5.9e-05 23.1 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase DUF1295 PF06966.12 KFY01394.1 - 1.3e-13 51.1 0.0 2e-13 50.5 0.0 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF1295) ERG4_ERG24 PF01222.17 KFY01394.1 - 4.5e-05 22.4 1.0 7.3e-05 21.7 1.1 1.5 1 1 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family Sugar_tr PF00083.24 KFY01395.1 - 3.2e-109 365.8 19.5 3.7e-109 365.6 19.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KFY01395.1 - 2.7e-21 75.9 32.3 5.9e-19 68.2 24.3 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2070 PF09843.9 KFY01395.1 - 1.1 7.5 5.2 1.8 6.7 5.2 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) Hexokinase_2 PF03727.16 KFY01396.1 - 4.6e-46 157.2 0.0 6.9e-46 156.6 0.0 1.3 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.21 KFY01396.1 - 3.5e-40 138.0 0.0 5.5e-40 137.4 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Glucosamine_iso PF01182.20 KFY01397.1 - 3.4e-22 79.4 0.0 5.6e-22 78.7 0.0 1.3 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase ABC2_membrane PF01061.24 KFY01398.1 - 9.6e-79 263.7 60.1 2.3e-42 144.8 19.4 2.8 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.27 KFY01398.1 - 2.7e-35 121.8 0.0 1e-17 64.9 0.0 2.4 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.12 KFY01398.1 - 5.3e-28 96.8 6.9 2.8e-23 81.6 0.0 3.9 3 0 0 3 3 2 2 CDR ABC transporter ABC_trans_N PF14510.6 KFY01398.1 - 2e-12 47.5 0.1 6.3e-12 45.9 0.1 1.9 1 0 0 1 1 1 1 ABC-transporter N-terminal ABC2_membrane_3 PF12698.7 KFY01398.1 - 5.9e-07 28.9 37.2 1.5e-05 24.3 17.3 2.6 2 1 0 2 2 2 2 ABC-2 family transporter protein AAA_33 PF13671.6 KFY01398.1 - 6.5e-06 26.4 0.1 0.0039 17.3 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_21 PF13304.6 KFY01398.1 - 7.5e-06 26.0 0.0 0.2 11.4 0.0 2.7 3 0 0 3 3 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_18 PF13238.6 KFY01398.1 - 5.2e-05 23.8 0.0 0.0049 17.4 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 KFY01398.1 - 5.4e-05 23.7 0.1 0.0058 17.0 0.0 2.5 2 0 0 2 2 2 1 AAA ATPase domain AAA_29 PF13555.6 KFY01398.1 - 0.00013 21.6 1.6 0.013 15.3 0.2 3.8 5 0 0 5 5 5 1 P-loop containing region of AAA domain AAA_25 PF13481.6 KFY01398.1 - 0.00023 20.8 0.2 0.0083 15.7 0.1 2.9 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.6 KFY01398.1 - 0.00025 21.5 0.1 0.024 15.0 0.0 2.4 2 0 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 KFY01398.1 - 0.00058 19.8 0.2 0.0018 18.2 0.0 1.8 2 0 0 2 2 2 1 RsgA GTPase SMC_N PF02463.19 KFY01398.1 - 0.0069 15.8 0.0 0.81 9.1 0.0 3.0 3 0 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_28 PF13521.6 KFY01398.1 - 0.009 16.3 0.0 0.067 13.4 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 KFY01398.1 - 0.013 15.3 0.1 1.9 8.1 0.0 2.5 2 0 0 2 2 2 0 AAA domain PduV-EutP PF10662.9 KFY01398.1 - 0.021 14.5 0.1 12 5.7 0.1 3.3 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation NACHT PF05729.12 KFY01398.1 - 0.025 14.5 0.3 4.4 7.2 0.1 2.4 2 0 0 2 2 2 0 NACHT domain AAA_22 PF13401.6 KFY01398.1 - 0.027 14.7 0.1 0.85 9.9 0.0 2.8 3 0 0 3 3 2 0 AAA domain cobW PF02492.19 KFY01398.1 - 0.063 12.9 1.6 0.48 10.0 0.3 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA PF00004.29 KFY01398.1 - 0.17 12.3 0.2 25 5.3 0.0 2.8 3 0 0 3 3 2 0 ATPase family associated with various cellular activities (AAA) CENP-Q PF13094.6 KFY01414.1 - 5.4e-44 150.4 8.2 5.4e-44 150.4 8.2 3.2 3 1 0 3 3 3 1 CENP-Q, a CENPA-CAD centromere complex subunit Totivirus_coat PF05518.11 KFY01414.1 - 8.8 4.2 13.1 15 3.4 13.1 1.3 1 0 0 1 1 1 0 Totivirus coat protein Zn_clus PF00172.18 KFY01415.1 - 4.9e-06 26.6 8.5 9.4e-06 25.7 8.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SPO22 PF08631.10 KFY01416.1 - 1e-49 169.5 8.3 1.2e-28 100.4 1.7 3.7 2 1 1 3 3 3 2 Meiosis protein SPO22/ZIP4 like TPR_19 PF14559.6 KFY01416.1 - 5.5e-07 30.0 0.0 8.1e-05 23.1 0.0 4.1 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.6 KFY01416.1 - 0.00019 21.7 4.1 0.094 13.0 0.0 4.5 4 1 0 4 4 4 2 Tetratricopeptide repeat MerR_2 PF13591.6 KFY01416.1 - 0.062 13.2 0.0 0.16 11.8 0.0 1.7 1 0 0 1 1 1 0 MerR HTH family regulatory protein GrpE PF01025.19 KFY01416.1 - 0.33 10.6 2.0 0.29 10.8 0.1 1.8 2 0 0 2 2 2 0 GrpE TPR_8 PF13181.6 KFY01416.1 - 1.3 9.5 6.8 23 5.5 0.1 4.8 4 1 1 5 5 5 0 Tetratricopeptide repeat TPR_2 PF07719.17 KFY01416.1 - 1.6 9.0 13.1 1.1 9.5 0.1 5.4 5 1 1 6 6 6 0 Tetratricopeptide repeat Ank_4 PF13637.6 KFY01417.1 - 6.4e-30 103.1 2.6 1.4e-09 38.2 0.0 7.5 6 2 3 9 9 9 4 Ankyrin repeats (many copies) Ank_2 PF12796.7 KFY01417.1 - 3e-25 88.6 2.7 1e-08 35.6 0.1 5.5 3 2 2 5 5 5 5 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KFY01417.1 - 1.9e-23 82.2 1.2 3e-07 30.6 0.3 5.5 4 1 1 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFY01417.1 - 1.1e-21 74.5 1.7 7.5e-05 22.8 0.0 7.5 7 1 0 7 7 7 4 Ankyrin repeat Ank PF00023.30 KFY01417.1 - 1.2e-21 76.1 7.9 0.00053 20.3 0.1 7.9 8 0 0 8 8 8 4 Ankyrin repeat YuzL PF14115.6 KFY01417.1 - 0.19 12.2 0.4 0.5 10.9 0.0 1.8 2 0 0 2 2 2 0 YuzL-like protein CtaG_Cox11 PF04442.14 KFY01419.1 - 6.2e-60 201.6 0.0 1.2e-59 200.7 0.0 1.5 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein CtaG/Cox11 C2 PF00168.30 KFY01419.1 - 1.9e-29 101.9 0.0 1.6e-18 66.8 0.0 2.7 2 0 0 2 2 2 2 C2 domain Sec6 PF06046.13 KFY01420.1 - 2.4e-168 561.1 3.9 3.5e-168 560.5 3.9 1.3 1 0 0 1 1 1 1 Exocyst complex component Sec6 AbiJ_NTD4 PF18863.1 KFY01420.1 - 0.029 14.9 3.0 0.53 10.7 0.2 2.8 3 0 0 3 3 3 0 AbiJ N-terminal domain 4 YgaB PF14182.6 KFY01420.1 - 0.1 13.0 2.2 0.29 11.5 0.1 2.8 1 1 2 3 3 3 0 YgaB-like protein DASH_Duo1 PF08651.10 KFY01420.1 - 0.17 11.7 0.8 6.5 6.6 0.2 3.3 1 1 1 2 2 2 0 DASH complex subunit Duo1 Noelin-1 PF12308.8 KFY01420.1 - 0.18 11.8 0.7 0.72 9.9 0.7 2.1 1 0 0 1 1 1 0 Neurogenesis glycoprotein CREPT PF16566.5 KFY01420.1 - 0.27 11.4 6.5 3.8 7.7 0.1 3.3 2 1 1 3 3 3 0 Cell-cycle alteration and expression-elevated protein in tumour Vps53_N PF04100.12 KFY01420.1 - 0.32 9.9 10.5 0.15 11.0 3.6 2.6 2 1 0 2 2 2 0 Vps53-like, N-terminal Ribosomal_L30 PF00327.20 KFY01421.1 - 3.6e-13 49.2 0.5 5.9e-13 48.5 0.5 1.4 1 0 0 1 1 1 1 Ribosomal protein L30p/L7e NUC173 PF08161.12 KFY01422.1 - 5.7e-80 267.8 1.9 2.8e-76 255.7 0.0 3.5 4 0 0 4 4 4 2 NUC173 domain HEAT_2 PF13646.6 KFY01422.1 - 0.035 14.5 2.3 0.71 10.3 0.1 4.1 3 1 1 4 4 4 0 HEAT repeats TFCD_C PF12612.8 KFY01422.1 - 0.06 13.2 7.7 1.7 8.4 0.1 5.0 4 2 1 5 5 5 0 Tubulin folding cofactor D C terminal Vac14_Fab1_bd PF12755.7 KFY01422.1 - 0.18 12.4 2.0 6.4 7.5 0.1 3.9 5 0 0 5 5 5 0 Vacuolar 14 Fab1-binding region XRN_M PF17846.1 KFY01422.1 - 2.4 7.0 6.2 0.5 9.3 0.1 2.3 2 0 0 2 2 2 0 Xrn1 helical domain ORC5_C PF14630.6 KFY01422.1 - 2.9 7.3 5.5 0.58 9.6 0.9 2.2 2 1 0 2 2 2 0 Origin recognition complex (ORC) subunit 5 C-terminus CorA PF01544.18 KFY01433.1 - 0.0042 16.4 0.1 0.0096 15.3 0.0 1.5 2 0 0 2 2 2 1 CorA-like Mg2+ transporter protein DIOX_N PF14226.6 KFY01434.1 - 1.5e-23 83.8 0.0 2.6e-23 83.0 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 KFY01434.1 - 1.4e-07 31.9 0.0 2.7e-07 31.0 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily AATase PF07247.12 KFY01435.1 - 2e-10 39.8 0.0 9.7e-06 24.4 0.0 3.1 3 0 0 3 3 3 3 Alcohol acetyltransferase GNVR PF13807.6 KFY01435.1 - 0.015 15.2 0.0 0.035 14.0 0.0 1.6 1 0 0 1 1 1 0 G-rich domain on putative tyrosine kinase NUMOD4 PF07463.11 KFY01435.1 - 0.11 12.7 0.0 0.22 11.7 0.0 1.5 1 0 0 1 1 1 0 NUMOD4 motif PAH PF02671.21 KFY01436.1 - 5.9e-08 32.7 0.0 1.4e-07 31.6 0.0 1.7 1 0 0 1 1 1 1 Paired amphipathic helix repeat ANAPC1 PF12859.7 KFY01436.1 - 0.038 14.6 2.0 0.079 13.5 2.0 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 1 Myb_CC_LHEQLE PF14379.6 KFY01437.1 - 0.029 14.1 0.5 0.094 12.4 0.5 1.8 1 0 0 1 1 1 0 MYB-CC type transfactor, LHEQLE motif F-box-like PF12937.7 KFY01453.1 - 0.00026 20.8 0.0 0.00054 19.8 0.0 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KFY01453.1 - 0.002 18.0 0.0 0.0043 16.9 0.0 1.6 1 0 0 1 1 1 1 F-box domain Methyltransf_23 PF13489.6 KFY01454.1 - 9.9e-17 61.3 0.0 1.6e-16 60.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KFY01454.1 - 3e-08 34.3 0.0 7.4e-08 33.0 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KFY01454.1 - 4.8e-05 23.2 0.0 0.00057 19.7 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KFY01454.1 - 6e-05 23.6 0.0 0.00015 22.4 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KFY01454.1 - 0.0053 16.1 0.0 0.021 14.2 0.0 1.9 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 KFY01454.1 - 0.013 16.3 0.0 0.044 14.5 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase domain FtsJ PF01728.19 KFY01454.1 - 0.019 15.1 0.0 0.027 14.6 0.0 1.3 1 0 0 1 1 1 0 FtsJ-like methyltransferase Glyco_tran_28_C PF04101.16 KFY01455.1 - 1.4e-13 51.1 0.0 1.3e-12 48.0 0.0 2.0 1 1 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain MRP-S28 PF10213.9 KFY01456.1 - 1.5e-46 157.9 0.1 3.1e-46 156.9 0.1 1.5 1 0 0 1 1 1 1 Mitochondrial ribosomal subunit protein FMN_red PF03358.15 KFY01458.1 - 1.4e-31 109.3 0.0 1.9e-31 108.9 0.0 1.1 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.17 KFY01458.1 - 5.3e-10 39.3 0.0 9.4e-10 38.5 0.0 1.5 2 0 0 2 2 2 1 Flavodoxin-like fold Lyase_1 PF00206.20 KFY01459.1 - 4.1e-86 289.2 0.0 5.7e-86 288.7 0.0 1.2 1 0 0 1 1 1 1 Lyase ASL_C2 PF14698.6 KFY01459.1 - 1.1e-21 77.4 0.1 2.4e-21 76.3 0.1 1.6 1 0 0 1 1 1 1 Argininosuccinate lyase C-terminal SPO22 PF08631.10 KFY01459.1 - 0.024 14.1 0.0 0.036 13.6 0.0 1.2 1 0 0 1 1 1 0 Meiosis protein SPO22/ZIP4 like Aldedh PF00171.22 KFY01460.1 - 8.3e-76 255.4 0.0 1e-75 255.1 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Yippee-Mis18 PF03226.14 KFY01462.1 - 1.9e-21 76.3 0.0 3.4e-21 75.4 0.0 1.3 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly DUF3446 PF11928.8 KFY01462.1 - 2.4 8.5 18.4 4.5 7.7 17.9 1.7 1 1 1 2 2 2 0 Early growth response N-terminal domain ODC_AZ PF02100.17 KFY01463.1 - 5.5e-41 139.1 0.1 7.9e-41 138.6 0.1 1.2 1 0 0 1 1 1 1 Ornithine decarboxylase antizyme Phage_int_SAM_1 PF02899.17 KFY01464.1 - 0.044 14.1 1.0 0.62 10.4 0.1 2.6 2 1 1 3 3 3 0 Phage integrase, N-terminal SAM-like domain DUF5457 PF17540.2 KFY01464.1 - 0.1 12.7 1.3 0.25 11.5 0.1 1.9 2 0 0 2 2 2 0 Family of unknown function (DUF5457) TFIIIC_sub6 PF10419.9 KFY01466.1 - 4.6e-25 87.3 0.1 1.8e-24 85.4 0.0 1.9 2 0 0 2 2 2 1 TFIIIC subunit triple barrel domain FA_desaturase PF00487.24 KFY01467.1 - 1.4e-13 51.3 17.9 2.6e-13 50.4 17.1 1.8 1 1 0 1 1 1 1 Fatty acid desaturase Aldedh PF00171.22 KFY01476.1 - 0.0092 14.5 1.1 0.011 14.3 1.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family TubC_N PF18563.1 KFY01476.1 - 0.14 12.1 0.4 0.5 10.4 0.1 1.9 2 0 0 2 2 2 0 TubC N-terminal docking domain PCI PF01399.27 KFY01477.1 - 0.0005 20.5 0.0 0.0013 19.2 0.0 1.7 1 0 0 1 1 1 1 PCI domain TPR_7 PF13176.6 KFY01477.1 - 0.0072 16.3 0.0 0.75 10.0 0.0 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat Rep_fac-A_C PF08646.10 KFY01478.1 - 5.6e-58 194.8 3.7 2.1e-56 189.7 0.8 2.3 2 0 0 2 2 2 2 Replication factor-A C terminal domain REPA_OB_2 PF16900.5 KFY01478.1 - 1.6e-37 127.3 1.4 6.3e-37 125.4 0.3 2.4 3 0 0 3 3 3 1 Replication protein A OB domain Rep-A_N PF04057.12 KFY01478.1 - 7.6e-22 77.2 0.0 1.7e-21 76.2 0.0 1.6 1 0 0 1 1 1 1 Replication factor-A protein 1, N-terminal domain tRNA_anti-codon PF01336.25 KFY01478.1 - 2.9e-16 59.2 0.2 1.6e-10 40.8 0.0 4.3 5 0 0 5 5 5 2 OB-fold nucleic acid binding domain CDC24_OB3 PF17244.2 KFY01478.1 - 0.0038 17.0 0.2 0.16 11.6 0.0 2.8 3 0 0 3 3 3 1 Cell division control protein 24, OB domain 3 DUF223 PF02721.14 KFY01478.1 - 0.0053 17.0 0.1 0.013 15.8 0.1 1.7 1 0 0 1 1 1 1 Domain of unknown function DUF223 PALP PF00291.25 KFY01479.1 - 3.6e-65 220.3 3.8 3.7e-50 171.0 2.3 2.1 1 1 1 2 2 2 2 Pyridoxal-phosphate dependent enzyme IlvN PF07991.12 KFY01480.1 - 2.8e-45 153.9 0.1 4.2e-45 153.3 0.1 1.2 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain IlvC PF01450.19 KFY01480.1 - 2.9e-40 137.9 0.0 4.4e-40 137.3 0.0 1.3 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain UQ_con PF00179.26 KFY01481.1 - 6.2e-39 132.9 0.0 7.9e-39 132.5 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Chitin_synth_1 PF01644.17 KFY01482.1 - 3.5e-69 231.9 0.1 5.3e-69 231.3 0.1 1.3 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.11 KFY01482.1 - 1.1e-28 98.9 0.1 3.6e-28 97.3 0.1 1.9 2 0 0 2 2 2 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.15 KFY01482.1 - 8.2e-23 80.8 1.0 1.4e-18 66.9 0.0 2.3 2 0 0 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.6 KFY01482.1 - 1.7e-08 34.6 0.0 1.7e-08 34.6 0.0 2.2 2 1 0 2 2 2 1 Glycosyl transferase family group 2 FRG2 PF15315.6 KFY01489.1 - 0.021 15.0 0.1 0.03 14.5 0.1 1.3 1 0 0 1 1 1 0 Facioscapulohumeral muscular dystrophy candidate 2 Ank_2 PF12796.7 KFY01490.1 - 5e-53 177.6 9.1 1.4e-12 48.0 0.0 4.6 2 2 3 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KFY01490.1 - 3e-40 136.1 3.6 2e-08 34.6 0.0 6.1 2 2 3 6 6 6 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFY01490.1 - 4.3e-39 128.1 9.9 6.9e-05 22.9 0.0 9.2 9 0 0 9 9 9 7 Ankyrin repeat Ank PF00023.30 KFY01490.1 - 1.3e-35 120.3 16.4 2.5e-05 24.5 0.1 8.8 9 0 0 9 9 9 8 Ankyrin repeat Ank_5 PF13857.6 KFY01490.1 - 7.3e-26 89.9 14.4 0.00036 20.8 0.0 6.6 2 2 5 7 7 7 7 Ankyrin repeats (many copies) SpoU_sub_bind PF08032.12 KFY01490.1 - 0.026 14.8 0.0 1.3e+02 3.0 0.0 5.1 6 0 0 6 6 6 0 RNA 2'-O ribose methyltransferase substrate binding Ribosomal_S20p PF01649.18 KFY01492.1 - 6.1 7.6 7.3 5.9 7.6 0.6 2.6 3 0 0 3 3 3 0 Ribosomal protein S20 Nipped-B_C PF12830.7 KFY01493.1 - 1.5e-34 119.6 2.9 2e-32 112.7 0.6 2.7 2 0 0 2 2 2 2 Sister chromatid cohesion C-terminus Cohesin_HEAT PF12765.7 KFY01493.1 - 0.0018 18.6 5.2 0.085 13.2 0.3 4.0 3 0 0 3 3 3 2 HEAT repeat associated with sister chromatid cohesion HEAT PF02985.22 KFY01493.1 - 0.0036 17.4 3.6 24 5.5 0.4 4.6 3 0 0 3 3 3 2 HEAT repeat HEAT_2 PF13646.6 KFY01493.1 - 0.01 16.2 1.1 0.15 12.4 0.3 3.3 3 0 0 3 3 3 0 HEAT repeats Adaptin_N PF01602.20 KFY01493.1 - 0.11 11.1 4.5 0.34 9.4 0.9 2.7 2 1 0 2 2 2 0 Adaptin N terminal region Rab15_effector PF15208.6 KFY01493.1 - 0.13 11.6 0.0 0.26 10.5 0.0 1.4 1 0 0 1 1 1 0 Rab15 effector Methyltransf_32 PF13679.6 KFY01496.1 - 1.5e-20 73.8 3.4 8.4e-20 71.4 3.4 2.0 1 1 0 1 1 1 1 Methyltransferase domain DUF669 PF05037.13 KFY01496.1 - 0.096 12.8 0.0 17 5.5 0.1 2.3 1 1 0 2 2 2 0 Protein of unknown function (DUF669) Syntaxin-6_N PF09177.11 KFY01497.1 - 8.9e-26 90.3 0.9 1.1e-24 86.9 0.1 2.2 2 0 0 2 2 2 1 Syntaxin 6, N-terminal Use1 PF09753.9 KFY01497.1 - 0.00041 20.1 0.4 0.00052 19.8 0.4 1.3 1 0 0 1 1 1 1 Membrane fusion protein Use1 SNARE PF05739.19 KFY01497.1 - 0.0035 17.3 3.8 0.0053 16.7 0.5 2.3 2 0 0 2 2 2 1 SNARE domain CdvA PF18822.1 KFY01497.1 - 0.021 14.6 1.2 0.26 11.1 0.1 2.3 2 0 0 2 2 2 0 CdvA-like coiled-coil domain DUF1664 PF07889.12 KFY01497.1 - 0.06 13.4 4.6 0.7 9.9 0.5 2.8 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) Tropomyosin_1 PF12718.7 KFY01497.1 - 0.061 13.5 10.5 0.066 13.4 8.6 1.8 1 1 0 1 1 1 0 Tropomyosin like Ada3 PF10198.9 KFY01497.1 - 0.13 12.4 4.9 0.99 9.5 4.9 2.2 1 1 0 1 1 1 0 Histone acetyltransferases subunit 3 UPF0242 PF06785.11 KFY01497.1 - 0.16 12.0 5.7 2 8.5 0.1 2.2 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus OmpH PF03938.14 KFY01497.1 - 0.24 11.7 11.5 4.6 7.6 11.5 2.3 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) Lipoprotein_20 PF13942.6 KFY01497.1 - 0.25 11.2 3.2 0.58 10.1 3.2 1.6 1 1 0 1 1 1 0 YfhG lipoprotein Adaptin_binding PF10199.9 KFY01497.1 - 0.29 11.8 7.1 3 8.5 7.1 2.2 1 1 0 1 1 1 0 Alpha and gamma adaptin binding protein p34 DUF2205 PF10224.9 KFY01497.1 - 3.3 7.8 7.7 4.1 7.5 0.0 3.4 3 1 0 3 3 3 0 Short coiled-coil protein Golgin_A5 PF09787.9 KFY01497.1 - 6.7 6.1 11.4 13 5.1 10.7 1.8 1 1 1 2 2 2 0 Golgin subfamily A member 5 B56 PF01603.20 KFY01498.1 - 1.7e-190 633.4 5.1 2e-190 633.1 5.1 1.1 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) Sec7_N PF12783.7 KFY01498.1 - 0.00081 19.3 2.0 0.33 10.8 0.0 2.4 2 0 0 2 2 2 2 Guanine nucleotide exchange factor in Golgi transport N-terminal SBF2 PF12335.8 KFY01498.1 - 0.14 11.7 0.1 0.37 10.4 0.1 1.6 1 0 0 1 1 1 0 Myotubularin protein Tau95 PF09734.9 KFY01499.1 - 2.6e-38 132.0 1.4 3.4e-38 131.6 0.2 1.8 2 0 0 2 2 2 1 RNA polymerase III transcription factor (TF)IIIC subunit HTH domain Tau95_N PF17682.1 KFY01499.1 - 6.1e-37 126.6 0.0 1.4e-36 125.5 0.0 1.6 1 0 0 1 1 1 1 Tau95 Triple barrel domain NOA36 PF06524.12 KFY01499.1 - 0.28 10.5 12.4 0.59 9.4 12.4 1.5 1 0 0 1 1 1 0 NOA36 protein NAP PF00956.18 KFY01500.1 - 1e-29 103.6 1.0 5.5e-28 97.9 0.3 2.0 1 1 1 2 2 2 2 Nucleosome assembly protein (NAP) PARG_cat PF05028.14 KFY01501.1 - 2.1e-55 188.4 0.0 2.8e-55 188.0 0.0 1.1 1 0 0 1 1 1 1 Poly (ADP-ribose) glycohydrolase (PARG) Cnd3 PF12719.7 KFY01502.1 - 1.4e-94 316.6 3.2 2.7e-94 315.6 0.5 2.7 3 1 0 3 3 3 1 Nuclear condensing complex subunits, C-term domain HEAT PF02985.22 KFY01502.1 - 3.9e-09 36.0 10.3 0.038 14.3 0.0 7.9 7 0 0 7 7 7 1 HEAT repeat HEAT_2 PF13646.6 KFY01502.1 - 1.7e-07 31.5 10.7 6.3e-05 23.3 1.9 4.4 5 1 0 5 5 5 2 HEAT repeats Cnd1 PF12717.7 KFY01502.1 - 5.6e-05 23.2 2.2 1.2 9.2 0.1 4.7 4 1 1 5 5 5 3 non-SMC mitotic condensation complex subunit 1 FANCI_HD1 PF14679.6 KFY01502.1 - 0.0084 16.1 0.1 0.67 9.9 0.0 3.4 3 0 0 3 3 3 1 FANCI helical domain 1 RTP1_C1 PF10363.9 KFY01502.1 - 0.029 14.6 3.5 14 5.9 0.1 4.5 3 2 1 4 4 4 0 Required for nuclear transport of RNA pol II C-terminus 1 V-ATPase_H_N PF03224.14 KFY01502.1 - 0.16 11.2 4.3 2.4 7.3 0.2 3.1 3 0 0 3 3 3 0 V-ATPase subunit H HEAT_EZ PF13513.6 KFY01502.1 - 1.8 9.2 10.5 0.54 10.8 0.3 5.2 6 2 1 7 7 7 0 HEAT-like repeat PALP PF00291.25 KFY01503.1 - 3.9e-67 226.7 0.3 4.5e-67 226.5 0.3 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme MtrG PF04210.13 KFY01504.1 - 0.15 11.9 0.0 0.92 9.4 0.0 2.1 2 0 0 2 2 2 0 Tetrahydromethanopterin S-methyltransferase, subunit G Ribosomal_L19 PF01245.20 KFY01505.1 - 4.6e-14 52.3 0.2 7.3e-14 51.6 0.2 1.4 1 0 0 1 1 1 1 Ribosomal protein L19 Pkinase PF00069.25 KFY01508.1 - 5.3e-71 239.1 0.0 7.6e-71 238.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFY01508.1 - 3.9e-35 121.4 0.0 7.3e-35 120.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 KFY01508.1 - 0.00019 20.9 0.1 0.00038 19.9 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 KFY01508.1 - 0.0069 15.7 0.1 0.016 14.6 0.1 1.5 1 1 1 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 KFY01508.1 - 0.015 14.2 0.3 0.096 11.6 0.0 1.9 2 0 0 2 2 2 0 Haspin like kinase domain Pkinase_fungal PF17667.1 KFY01508.1 - 0.051 12.4 0.0 0.051 12.4 0.0 3.8 4 1 0 4 4 4 0 Fungal protein kinase Peptidase_C65 PF10275.9 KFY01536.1 - 1.7e-30 106.3 0.0 3e-18 66.2 0.0 2.2 1 1 1 2 2 2 2 Peptidase C65 Otubain SET PF00856.28 KFY01546.1 - 6.6e-15 55.9 0.0 1.3e-14 55.0 0.0 1.5 1 0 0 1 1 1 1 SET domain OrsD PF12013.8 KFY01547.1 - 0.0038 17.7 0.6 0.0071 16.8 0.1 1.7 2 0 0 2 2 2 1 Orsellinic acid/F9775 biosynthesis cluster protein D FlxA PF14282.6 KFY01554.1 - 0.05 13.6 0.0 0.11 12.6 0.0 1.5 1 0 0 1 1 1 0 FlxA-like protein ADIP PF11559.8 KFY01554.1 - 0.096 12.8 3.2 0.16 12.1 3.2 1.3 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding FliJ PF02050.16 KFY01554.1 - 0.11 12.7 3.4 0.23 11.7 3.4 1.5 1 0 0 1 1 1 0 Flagellar FliJ protein ABC_tran_CTD PF16326.5 KFY01554.1 - 0.14 12.4 0.1 0.46 10.8 0.1 1.8 1 0 0 1 1 1 0 ABC transporter C-terminal domain RRM_1 PF00076.22 KFY01555.1 - 6.2e-42 141.3 0.3 2.1e-18 65.9 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RBM39linker PF15519.6 KFY01555.1 - 1.8e-23 83.5 1.9 2.6e-23 82.9 0.0 2.4 3 0 0 3 3 3 1 linker between RRM2 and RRM3 domains in RBM39 protein RRM_occluded PF16842.5 KFY01555.1 - 0.00014 21.6 0.0 1.3 8.9 0.0 3.2 3 0 0 3 3 3 2 Occluded RNA-recognition motif PHM7_cyt PF14703.6 KFY01555.1 - 0.0035 17.6 0.1 0.72 10.1 0.1 3.2 1 1 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter Nup35_RRM_2 PF14605.6 KFY01555.1 - 0.018 15.1 0.0 5.8 7.0 0.0 3.1 3 0 0 3 3 3 0 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.11 KFY01555.1 - 0.02 14.9 0.0 0.17 12.0 0.0 2.3 2 0 0 2 2 2 0 RNA binding motif RRM_7 PF16367.5 KFY01555.1 - 0.063 13.4 0.1 5.8 7.1 0.0 2.5 2 0 0 2 2 2 0 RNA recognition motif Cyt-b5 PF00173.28 KFY01556.1 - 1.2e-17 63.8 0.1 1.2e-17 63.8 0.1 2.2 3 0 0 3 3 3 1 Cytochrome b5-like Heme/Steroid binding domain FA_hydroxylase PF04116.13 KFY01556.1 - 5.5e-12 46.2 18.9 6.1e-12 46.0 18.1 1.5 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily Anth_synt_I_N PF04715.13 KFY01556.1 - 0.0041 17.3 0.1 0.015 15.5 0.1 1.8 2 0 0 2 2 2 1 Anthranilate synthase component I, N terminal region Diphtheria_C PF02763.14 KFY01556.1 - 0.081 12.6 0.1 0.13 11.9 0.1 1.2 1 0 0 1 1 1 0 Diphtheria toxin, C domain Flu_M1 PF00598.19 KFY01556.1 - 0.12 11.9 0.0 0.2 11.2 0.0 1.3 1 0 0 1 1 1 0 Influenza Matrix protein (M1) Het-C PF07217.11 KFY01557.1 - 4.3e-274 910.3 0.0 5.1e-274 910.0 0.0 1.0 1 0 0 1 1 1 1 Heterokaryon incompatibility protein Het-C RRM_1 PF00076.22 KFY01567.1 - 2.5e-53 177.8 0.0 1.5e-17 63.2 0.0 3.9 3 1 1 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KFY01567.1 - 2.3e-05 24.0 0.0 0.016 14.8 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 KFY01567.1 - 2.8e-05 24.1 0.0 1 9.5 0.0 3.3 3 0 0 3 3 3 2 RNA binding motif Limkain-b1 PF11608.8 KFY01567.1 - 3e-05 24.0 0.2 3.9 7.6 0.0 4.1 4 1 0 4 4 4 3 Limkain b1 ATP-grasp_2 PF08442.10 KFY01567.1 - 0.00051 19.7 0.0 0.038 13.6 0.0 2.9 3 0 0 3 3 3 1 ATP-grasp domain RRM_occluded PF16842.5 KFY01567.1 - 0.13 12.2 0.0 8.4 6.3 0.0 3.0 3 0 0 3 3 3 0 Occluded RNA-recognition motif DUF3343 PF11823.8 KFY01567.1 - 0.19 11.2 0.0 0.48 9.9 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3343) MIF4G PF02854.19 KFY01568.1 - 3.7e-21 75.8 0.3 6.5e-21 74.9 0.3 1.4 1 0 0 1 1 1 1 MIF4G domain MA3 PF02847.17 KFY01568.1 - 6.3e-21 74.5 0.0 1.2e-20 73.6 0.0 1.5 1 0 0 1 1 1 1 MA3 domain RAMP4 PF06624.12 KFY01568.1 - 0.5 10.5 3.0 12 6.0 1.7 2.6 2 0 0 2 2 2 0 Ribosome associated membrane protein RAMP4 SRP14 PF02290.15 KFY01569.1 - 4.6e-31 107.1 0.2 6.6e-31 106.5 0.0 1.4 2 0 0 2 2 2 1 Signal recognition particle 14kD protein Pyr_redox_2 PF07992.14 KFY01570.1 - 7.8e-69 232.1 10.1 1.5e-68 231.2 8.4 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 KFY01570.1 - 1.1e-40 138.2 0.2 3.6e-40 136.6 0.2 1.9 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 KFY01570.1 - 3.2e-21 75.7 12.8 9.7e-19 67.7 1.0 3.6 4 0 0 4 4 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KFY01570.1 - 7.5e-10 38.9 5.0 2.6e-06 27.6 0.9 2.6 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.7 KFY01570.1 - 9.5e-10 38.4 0.7 9.5e-10 38.4 0.7 3.0 2 1 1 3 3 3 1 FAD dependent oxidoreductase GIDA PF01134.22 KFY01570.1 - 1e-09 38.0 8.6 7.6e-09 35.1 2.1 2.4 2 0 0 2 2 2 2 Glucose inhibited division protein A FAD_binding_2 PF00890.24 KFY01570.1 - 1.2e-07 31.2 11.3 1.7e-07 30.7 3.8 2.9 3 0 0 3 3 3 1 FAD binding domain FAD_binding_3 PF01494.19 KFY01570.1 - 7.5e-07 28.7 5.5 0.0044 16.3 0.1 2.4 2 0 0 2 2 2 2 FAD binding domain Pyr_redox_3 PF13738.6 KFY01570.1 - 1.3e-06 27.9 5.9 0.0006 19.2 0.5 2.6 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 KFY01570.1 - 2.8e-06 26.8 7.1 0.0037 16.6 0.7 2.8 2 1 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain Thi4 PF01946.17 KFY01570.1 - 3.1e-06 26.6 3.6 4.5e-05 22.8 0.1 2.3 2 0 0 2 2 2 1 Thi4 family HI0933_like PF03486.14 KFY01570.1 - 4.2e-05 22.4 17.0 7.5e-05 21.6 2.3 4.0 4 0 0 4 4 4 1 HI0933-like protein DAO PF01266.24 KFY01570.1 - 0.00012 21.8 18.3 0.00047 19.8 0.6 4.2 4 0 0 4 4 4 1 FAD dependent oxidoreductase K_oxygenase PF13434.6 KFY01570.1 - 0.00027 20.2 1.0 0.8 8.8 0.0 3.0 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Lycopene_cycl PF05834.12 KFY01570.1 - 0.0025 17.0 2.3 0.013 14.5 0.0 2.4 2 0 0 2 2 2 1 Lycopene cyclase protein NAD_binding_7 PF13241.6 KFY01570.1 - 0.014 15.8 3.6 2.2 8.7 0.5 2.8 2 1 0 2 2 2 0 Putative NAD(P)-binding THF_DHG_CYH_C PF02882.19 KFY01570.1 - 0.055 12.8 1.1 1.2 8.5 0.1 3.2 3 0 0 3 3 3 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain FMO-like PF00743.19 KFY01570.1 - 0.22 9.9 0.7 0.35 9.2 0.7 1.2 1 0 0 1 1 1 0 Flavin-binding monooxygenase-like Trp_halogenase PF04820.14 KFY01570.1 - 3.7 6.3 9.7 0.029 13.2 1.2 1.7 2 0 0 2 2 2 0 Tryptophan halogenase 3HCDH_N PF02737.18 KFY01570.1 - 6.6 6.6 8.7 2.5 8.0 0.8 2.4 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.14 KFY01570.1 - 8.5 5.9 6.9 11 5.5 0.4 2.3 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Gamma-thionin PF00304.20 KFY01584.1 - 6.1e-05 23.2 47.1 0.18 12.1 3.5 5.4 5 0 0 5 5 5 4 Gamma-thionin family Ion_trans_2 PF07885.16 KFY01584.1 - 0.25 11.3 2.4 2.6e+02 1.7 0.0 4.6 5 0 0 5 5 5 0 Ion channel Methyltransf_25 PF13649.6 KFY01585.1 - 3.9e-10 40.3 0.0 6.1e-10 39.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KFY01585.1 - 2.5e-09 37.1 0.0 3e-09 36.9 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 KFY01585.1 - 1.9e-06 27.4 0.0 2.2e-06 27.2 0.0 1.3 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_11 PF08241.12 KFY01585.1 - 2.5e-06 28.1 0.0 3.7e-06 27.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KFY01585.1 - 2.4e-05 23.9 0.1 4.2e-05 23.1 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_12 PF08242.12 KFY01585.1 - 5.7e-05 23.8 0.0 9.8e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KFY01585.1 - 0.00014 21.7 0.0 0.00025 20.9 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 KFY01585.1 - 0.0012 18.3 0.1 0.0019 17.6 0.1 1.3 1 1 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MetW PF07021.12 KFY01585.1 - 0.006 16.2 0.1 0.014 15.0 0.1 1.6 2 0 0 2 2 2 1 Methionine biosynthesis protein MetW Methyltransf_32 PF13679.6 KFY01585.1 - 0.023 14.7 0.0 0.026 14.5 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain DUF3446 PF11928.8 KFY01588.1 - 0.0034 17.6 3.6 0.0034 17.6 3.6 2.2 2 0 0 2 2 2 2 Early growth response N-terminal domain GMC_oxred_N PF00732.19 KFY01589.1 - 3.8e-50 170.9 0.1 4.8e-50 170.6 0.1 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KFY01589.1 - 9.2e-37 126.8 0.1 1.5e-36 126.0 0.1 1.4 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.24 KFY01589.1 - 5.4e-06 26.2 1.2 0.0002 21.1 0.5 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 KFY01589.1 - 7.6e-06 25.4 0.0 0.056 12.7 0.2 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KFY01589.1 - 1.7e-05 24.1 0.1 0.00063 18.9 0.0 2.2 2 0 0 2 2 2 1 Lycopene cyclase protein NAD_binding_9 PF13454.6 KFY01589.1 - 0.00017 21.6 0.2 0.16 11.9 0.1 2.3 2 0 0 2 2 2 2 FAD-NAD(P)-binding Pyr_redox_2 PF07992.14 KFY01589.1 - 0.001 18.4 0.2 0.041 13.1 0.0 2.6 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KFY01589.1 - 0.0011 19.1 0.2 0.0029 17.8 0.2 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain GIDA PF01134.22 KFY01589.1 - 0.0045 16.1 0.3 0.64 9.0 0.0 2.2 2 0 0 2 2 2 2 Glucose inhibited division protein A FAD_binding_2 PF00890.24 KFY01589.1 - 0.014 14.5 0.1 0.026 13.6 0.1 1.4 1 0 0 1 1 1 0 FAD binding domain Thi4 PF01946.17 KFY01589.1 - 0.016 14.5 0.0 0.036 13.3 0.0 1.5 1 0 0 1 1 1 0 Thi4 family Trp_halogenase PF04820.14 KFY01589.1 - 0.051 12.4 0.1 0.077 11.8 0.1 1.2 1 0 0 1 1 1 0 Tryptophan halogenase HI0933_like PF03486.14 KFY01589.1 - 0.16 10.7 0.2 0.34 9.5 0.1 1.6 2 0 0 2 2 2 0 HI0933-like protein Amidohydro_2 PF04909.14 KFY01591.1 - 1.6e-45 156.2 0.4 2e-45 155.8 0.4 1.1 1 0 0 1 1 1 1 Amidohydrolase Retrotran_gag_2 PF14223.6 KFY01591.1 - 0.17 11.6 0.1 0.3 10.7 0.1 1.3 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type COesterase PF00135.28 KFY01592.1 - 1.1e-74 252.2 0.0 1.6e-74 251.6 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KFY01592.1 - 0.016 15.1 0.0 0.061 13.2 0.0 1.9 1 1 0 1 1 1 0 alpha/beta hydrolase fold Sugar_tr PF00083.24 KFY01594.1 - 2.4e-86 290.4 16.6 2.8e-86 290.2 16.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KFY01594.1 - 6.9e-16 58.1 25.9 8.2e-12 44.7 22.9 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily Peptidase_M56 PF05569.11 KFY01594.1 - 0.15 11.2 1.2 0.32 10.2 1.2 1.5 1 0 0 1 1 1 0 BlaR1 peptidase M56 Wzy_C PF04932.15 KFY01594.1 - 0.82 9.3 7.7 0.57 9.8 3.1 2.3 2 0 0 2 2 2 0 O-Antigen ligase Alpha-amylase PF00128.24 KFY01595.1 - 3.8e-112 375.2 1.5 5.2e-112 374.7 1.5 1.1 1 0 0 1 1 1 1 Alpha amylase, catalytic domain Malt_amylase_C PF16657.5 KFY01595.1 - 5.3e-05 23.2 0.0 0.00013 22.1 0.0 1.6 1 0 0 1 1 1 1 Maltogenic Amylase, C-terminal domain hDGE_amylase PF14701.6 KFY01595.1 - 0.011 14.8 0.0 0.019 14.0 0.0 1.3 1 0 0 1 1 1 0 Glycogen debranching enzyme, glucanotransferase domain DUF3459 PF11941.8 KFY01595.1 - 0.019 15.3 0.0 0.039 14.3 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3459) Amidase PF01425.21 KFY01596.1 - 0.00042 19.4 0.0 0.00043 19.4 0.0 1.0 1 0 0 1 1 1 1 Amidase MFS_1 PF07690.16 KFY01597.1 - 8.1e-24 84.2 30.2 4.2e-22 78.5 33.8 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily Fungal_trans_2 PF11951.8 KFY01598.1 - 3.9e-06 25.9 0.1 1.1e-05 24.5 0.1 1.7 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KFY01598.1 - 0.0001 22.3 11.3 0.00021 21.3 11.3 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HET PF06985.11 KFY01599.1 - 8.6e-05 22.9 0.0 0.00022 21.6 0.0 1.6 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Bac_luciferase PF00296.20 KFY01600.1 - 2.1e-53 181.8 0.6 3.5e-53 181.1 0.6 1.3 1 0 0 1 1 1 1 Luciferase-like monooxygenase UNC-93 PF05978.16 KFY01600.1 - 0.00076 19.2 2.7 0.00076 19.2 2.7 2.9 2 1 1 3 3 3 1 Ion channel regulatory protein UNC-93 Methyltrn_RNA_3 PF02598.17 KFY01600.1 - 0.044 13.3 0.0 0.071 12.6 0.0 1.2 1 0 0 1 1 1 0 Putative RNA methyltransferase MFS_1 PF07690.16 KFY01600.1 - 0.56 9.1 41.5 16 4.3 41.5 2.2 1 1 0 1 1 1 0 Major Facilitator Superfamily FMO-like PF00743.19 KFY01601.1 - 1.5e-16 59.9 0.0 1.8e-15 56.4 0.0 2.3 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 KFY01601.1 - 2.1e-13 50.1 0.0 7.2e-12 45.1 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KFY01601.1 - 3.5e-12 46.2 0.0 3.3e-11 43.0 0.0 2.4 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KFY01601.1 - 8.9e-10 38.7 0.0 5.8e-09 36.1 0.0 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.6 KFY01601.1 - 2.9e-08 33.2 0.5 1.8e-07 30.6 0.0 2.2 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.24 KFY01601.1 - 1.1e-05 25.3 2.0 0.22 11.1 0.1 3.3 3 1 0 3 3 3 3 FAD dependent oxidoreductase Thi4 PF01946.17 KFY01601.1 - 1.6e-05 24.2 0.1 6.6e-05 22.3 0.0 1.9 2 0 0 2 2 2 1 Thi4 family NAD_binding_9 PF13454.6 KFY01601.1 - 0.0029 17.6 0.4 0.32 11.0 0.0 3.4 3 1 1 4 4 4 1 FAD-NAD(P)-binding AlaDh_PNT_C PF01262.21 KFY01601.1 - 0.19 11.0 1.2 0.28 10.4 0.1 1.8 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain F-box PF00646.33 KFY01602.1 - 0.00019 21.2 0.6 0.00039 20.2 0.6 1.5 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 KFY01602.1 - 0.052 13.5 0.1 0.09 12.7 0.1 1.4 1 0 0 1 1 1 0 F-box-like VID27 PF08553.10 KFY01603.1 - 7.5e-196 650.2 0.1 9.9e-196 649.8 0.1 1.1 1 0 0 1 1 1 1 VID27 C-terminal WD40-like domain VID27_N PF17748.1 KFY01603.1 - 2.6e-74 248.8 0.5 2.6e-74 248.8 0.5 2.6 2 1 0 2 2 2 1 VID27 N-terminal region VID27_PH PF17747.1 KFY01603.1 - 1.1e-47 160.8 1.9 3.4e-47 159.2 1.1 2.1 2 0 0 2 2 2 1 VID27 PH-like domain Glyco_transf_20 PF00982.21 KFY01604.1 - 2.3e-196 653.1 0.0 2.7e-196 652.9 0.0 1.0 1 0 0 1 1 1 1 Glycosyltransferase family 20 Glyco_trans_1_4 PF13692.6 KFY01604.1 - 0.001 19.5 0.0 0.0023 18.4 0.0 1.6 1 1 0 1 1 1 1 Glycosyl transferases group 1 Drc1-Sld2 PF11719.8 KFY01605.1 - 1.1e-90 305.4 16.5 1.3e-90 305.2 16.5 1.0 1 0 0 1 1 1 1 DNA replication and checkpoint protein HECT PF00632.25 KFY01606.1 - 1.5e-64 218.4 0.0 2.3e-64 217.8 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) MFS_1 PF07690.16 KFY01606.1 - 1.2e-35 123.1 27.4 1.2e-35 123.1 27.4 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily AZUL PF16558.5 KFY01606.1 - 3.4e-19 68.8 2.4 7.2e-19 67.8 2.4 1.6 1 0 0 1 1 1 1 Amino-terminal Zinc-binding domain of ubiquitin ligase E3A Sugar_tr PF00083.24 KFY01606.1 - 1.5e-08 33.9 7.3 1.5e-08 33.9 7.3 2.0 2 0 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.13 KFY01606.1 - 0.00059 18.4 4.2 0.00097 17.7 4.2 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Asp PF00026.23 KFY01608.1 - 8.4e-71 239.0 8.5 9.9e-71 238.7 8.5 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KFY01608.1 - 1.8e-11 44.6 6.1 5.7e-05 23.4 1.7 2.6 2 1 1 3 3 3 2 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 KFY01608.1 - 5.8e-05 23.6 3.6 0.0017 18.9 1.3 3.2 2 1 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.6 KFY01608.1 - 0.044 14.3 0.9 0.26 11.9 0.2 2.5 2 1 0 2 2 2 0 gag-polyprotein putative aspartyl protease Mannosidase_ig PF17786.1 KFY01610.1 - 7.5e-09 36.1 0.0 8.2e-08 32.8 0.0 2.4 2 0 0 2 2 2 1 Mannosidase Ig/CBM-like domain Glyco_hydro_2 PF00703.21 KFY01610.1 - 5.1e-08 33.6 0.0 1.5e-07 32.1 0.0 1.8 1 0 0 1 1 1 1 Glycosyl hydrolases family 2 Glyco_hydro_2_C PF02836.17 KFY01610.1 - 0.004 16.3 0.2 0.016 14.3 0.2 1.8 1 1 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Glyco_hydro_2_N PF02837.18 KFY01610.1 - 0.017 15.0 0.0 0.033 14.1 0.0 1.4 1 0 0 1 1 1 0 Glycosyl hydrolases family 2, sugar binding domain Sugar_tr PF00083.24 KFY01611.1 - 9.4e-87 291.7 34.8 1.2e-86 291.4 34.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KFY01611.1 - 3.9e-33 114.8 34.4 3.9e-33 114.8 34.4 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 KFY01611.1 - 0.00049 18.7 3.6 0.00049 18.7 3.6 2.1 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) 7TM_GPCR_Srw PF10324.9 KFY01611.1 - 0.0064 15.8 1.8 0.0064 15.8 1.8 1.9 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srw DUF3413 PF11893.8 KFY01611.1 - 0.027 13.6 0.2 0.027 13.6 0.2 2.9 2 1 0 2 2 2 0 Domain of unknown function (DUF3413) Fungal_trans PF04082.18 KFY01612.1 - 4.8e-13 48.7 0.8 6.8e-13 48.3 0.8 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.26 KFY01612.1 - 0.00023 21.4 1.7 0.00054 20.3 1.7 1.7 1 0 0 1 1 1 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFY01612.1 - 0.0017 19.0 1.0 0.0051 17.5 1.0 1.9 1 0 0 1 1 1 1 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 KFY01612.1 - 0.17 12.2 0.4 0.54 10.6 0.4 1.9 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding PspB PF06667.12 KFY01613.1 - 0.12 12.5 0.2 0.27 11.3 0.2 1.7 1 0 0 1 1 1 0 Phage shock protein B PMP1_2 PF08114.11 KFY01613.1 - 0.47 10.2 4.4 0.78 9.5 4.4 1.3 1 0 0 1 1 1 0 ATPase proteolipid family WD40 PF00400.32 KFY01614.1 - 3.4e-53 176.4 15.4 7e-09 36.2 0.4 8.5 8 1 0 8 8 8 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFY01614.1 - 3.7e-14 52.8 0.1 0.00023 21.4 0.0 4.3 2 1 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KFY01614.1 - 1.7e-07 30.3 4.2 0.00041 19.1 0.7 4.1 3 1 0 4 4 4 2 Nucleoporin Nup120/160 Nucleoporin_N PF08801.11 KFY01614.1 - 2.7e-05 23.1 0.0 0.016 14.0 0.0 2.5 3 0 0 3 3 3 2 Nup133 N terminal like Pox_A_type_inc PF04508.12 KFY01614.1 - 0.17 11.8 0.1 0.38 10.7 0.1 1.6 1 0 0 1 1 1 0 Viral A-type inclusion protein repeat Glyco_hydro_18 PF00704.28 KFY01615.1 - 7.8e-47 160.5 3.5 1.4e-46 159.6 3.5 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 LysM PF01476.20 KFY01615.1 - 1.6e-05 24.8 0.1 0.013 15.5 0.2 2.6 2 0 0 2 2 2 2 LysM domain Chitin_bind_1 PF00187.19 KFY01615.1 - 0.00033 21.1 8.0 0.00033 21.1 8.0 3.5 3 0 0 3 3 3 1 Chitin recognition protein 2Fe-2S_thioredx PF01257.19 KFY01616.1 - 1.2e-59 200.3 0.1 1.7e-59 199.8 0.1 1.2 1 0 0 1 1 1 1 Thioredoxin-like [2Fe-2S] ferredoxin MARVEL PF01284.23 KFY01616.1 - 1.9e-17 63.6 10.2 2.8e-17 63.1 10.2 1.2 1 0 0 1 1 1 1 Membrane-associating domain FAD_binding_3 PF01494.19 KFY01621.1 - 1.1e-25 90.6 0.0 4.7e-24 85.3 0.0 2.1 1 1 0 1 1 1 1 FAD binding domain POLO_box PF00659.18 KFY01621.1 - 1.6e-07 31.4 0.2 0.00018 21.6 0.0 2.9 2 0 0 2 2 2 2 POLO box duplicated region Lycopene_cycl PF05834.12 KFY01621.1 - 6.2e-07 28.8 0.4 2.8e-05 23.3 0.1 2.8 2 1 0 2 2 2 1 Lycopene cyclase protein DAO PF01266.24 KFY01621.1 - 0.00029 20.6 0.4 0.09 12.3 0.2 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KFY01621.1 - 0.00033 20.0 0.0 0.0012 18.1 0.0 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KFY01621.1 - 0.002 17.4 0.0 0.019 14.2 0.0 2.0 2 0 0 2 2 2 1 Thi4 family FAD_oxidored PF12831.7 KFY01621.1 - 0.0038 16.6 0.0 0.0086 15.5 0.0 1.6 1 0 0 1 1 1 1 FAD dependent oxidoreductase Trp_halogenase PF04820.14 KFY01621.1 - 0.0046 15.9 0.0 0.077 11.8 0.0 2.6 3 0 0 3 3 3 1 Tryptophan halogenase HI0933_like PF03486.14 KFY01621.1 - 0.006 15.3 0.1 0.014 14.1 0.1 1.5 1 1 0 1 1 1 1 HI0933-like protein SE PF08491.10 KFY01621.1 - 0.0072 15.4 0.0 0.012 14.7 0.0 1.2 1 0 0 1 1 1 1 Squalene epoxidase NAD_binding_9 PF13454.6 KFY01621.1 - 0.012 15.6 0.0 0.024 14.6 0.0 1.5 1 0 0 1 1 1 0 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 KFY01621.1 - 0.023 14.9 0.3 0.065 13.5 0.3 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 KFY01621.1 - 0.063 12.3 0.4 0.1 11.7 0.4 1.3 1 0 0 1 1 1 0 FAD binding domain Pyr_redox PF00070.27 KFY01621.1 - 0.1 13.2 0.3 7.3 7.2 0.0 2.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Asp_protease_2 PF13650.6 KFY01622.1 - 1.9e-06 28.4 0.0 3.7e-06 27.5 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 KFY01622.1 - 1.4e-05 25.6 0.0 2.4e-05 24.8 0.0 1.3 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP PF00077.20 KFY01622.1 - 0.0035 17.6 0.0 0.0062 16.8 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 KFY01623.1 - 2.3e-06 28.1 0.0 3.7e-06 27.5 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 KFY01623.1 - 8.4e-06 26.3 0.0 1.4e-05 25.5 0.0 1.4 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP PF00077.20 KFY01623.1 - 0.14 12.5 0.0 0.21 11.9 0.0 1.4 1 0 0 1 1 1 0 Retroviral aspartyl protease Pkinase PF00069.25 KFY01624.1 - 1e-50 172.5 0.0 1.5e-50 172.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFY01624.1 - 2.8e-38 131.7 0.0 4.4e-38 131.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KFY01624.1 - 0.0006 18.7 0.0 0.0014 17.4 0.0 1.5 1 0 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 KFY01624.1 - 0.0028 16.7 0.0 0.055 12.4 0.0 2.0 2 0 0 2 2 2 1 Haspin like kinase domain APH PF01636.23 KFY01624.1 - 0.0058 16.6 0.0 0.028 14.4 0.0 1.9 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 KFY01624.1 - 0.028 13.8 0.0 0.049 13.0 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 KFY01624.1 - 0.038 13.3 0.0 0.084 12.2 0.0 1.5 2 0 0 2 2 2 0 Kinase-like RRN3 PF05327.11 KFY01625.1 - 4.6e-179 596.6 0.0 4.6e-179 596.6 0.0 2.0 2 0 0 2 2 2 1 RNA polymerase I specific transcription initiation factor RRN3 eIF-3c_N PF05470.12 KFY01625.1 - 2.2 6.5 6.9 4.2 5.5 4.6 2.0 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus Sigma70_ner PF04546.13 KFY01625.1 - 3 7.7 18.3 2.7 7.8 2.3 2.5 2 0 0 2 2 2 0 Sigma-70, non-essential region Prefoldin_2 PF01920.20 KFY01626.1 - 7.1e-26 90.2 5.8 8.4e-26 90.0 5.8 1.1 1 0 0 1 1 1 1 Prefoldin subunit DUF2205 PF10224.9 KFY01626.1 - 0.027 14.5 2.0 0.027 14.5 2.0 2.2 2 0 0 2 2 2 0 Short coiled-coil protein HBB PF06777.11 KFY01626.1 - 0.054 13.2 1.4 1.3 8.6 1.4 2.0 1 1 0 1 1 1 0 Helical and beta-bridge domain Cytochrom_B562 PF07361.11 KFY01626.1 - 0.089 13.5 1.9 0.089 13.5 1.9 1.8 2 0 0 2 2 2 0 Cytochrome b562 SLATT_1 PF18181.1 KFY01626.1 - 0.12 12.3 2.8 0.19 11.7 0.9 1.9 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain 1 Metal_resist PF13801.6 KFY01626.1 - 0.17 12.1 0.9 0.28 11.4 0.9 1.3 1 0 0 1 1 1 0 Heavy-metal resistance Cmc1 PF08583.10 KFY01627.1 - 1.8e-18 66.3 3.0 2.1e-18 66.1 3.0 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like Flu_B_M2 PF04772.12 KFY01627.1 - 0.021 15.0 0.0 0.024 14.9 0.0 1.1 1 0 0 1 1 1 0 Influenza B matrix protein 2 (BM2) NADPH_Ox PF08414.10 KFY01627.1 - 0.024 15.0 0.1 0.029 14.7 0.1 1.1 1 0 0 1 1 1 0 Respiratory burst NADPH oxidase Tmemb_14 PF03647.13 KFY01628.1 - 1.8e-23 83.1 9.4 2e-23 82.9 9.4 1.0 1 0 0 1 1 1 1 Transmembrane proteins 14C Aim19 PF10315.9 KFY01628.1 - 0.12 12.6 2.1 1.7 9.0 2.1 2.2 1 1 0 1 1 1 0 Altered inheritance of mitochondria protein 19 DAD PF02109.16 KFY01629.1 - 6.5e-52 174.4 3.6 7.8e-52 174.2 3.6 1.1 1 0 0 1 1 1 1 DAD family Arb2 PF09757.9 KFY01629.1 - 0.0028 16.8 0.0 0.0035 16.5 0.0 1.1 1 0 0 1 1 1 1 Arb2 domain Zn_clus PF00172.18 KFY01630.1 - 0.00011 22.3 12.4 0.00018 21.6 12.4 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KFY01630.1 - 0.038 13.0 1.9 0.21 10.6 0.2 2.3 2 0 0 2 2 2 0 Fungal specific transcription factor domain Herpes_UL14 PF03580.14 KFY01630.1 - 0.17 12.1 0.4 0.71 10.1 0.0 2.0 2 0 0 2 2 2 0 Herpesvirus UL14-like protein ThiS PF02597.20 KFY01631.1 - 1.7e-10 41.4 0.0 3.4e-10 40.4 0.0 1.5 1 1 0 1 1 1 1 ThiS family RNB PF00773.19 KFY01632.1 - 7.2e-52 176.7 0.0 2.1e-50 171.9 0.0 2.1 1 1 0 1 1 1 1 RNB domain SprT-like PF10263.9 KFY01641.1 - 0.0017 18.2 0.0 0.0042 16.9 0.0 1.7 1 1 0 1 1 1 1 SprT-like family Peptidase_M50B PF13398.6 KFY01641.1 - 0.22 11.2 0.0 0.33 10.6 0.0 1.2 1 0 0 1 1 1 0 Peptidase M50B-like RGS PF00615.19 KFY01642.1 - 6.1e-12 45.9 0.0 1e-08 35.4 0.0 2.2 2 0 0 2 2 2 2 Regulator of G protein signaling domain Ribosomal_L31e PF01198.19 KFY01643.1 - 1.8e-39 133.9 0.8 3.4e-39 132.9 0.2 1.8 2 0 0 2 2 2 1 Ribosomal protein L31e NOG1_N PF17835.1 KFY01643.1 - 0.0086 16.0 0.8 0.017 15.1 0.8 1.5 1 1 0 1 1 1 1 NOG1 N-terminal helical domain UQ_con PF00179.26 KFY01644.1 - 1.2e-47 161.0 0.0 1.4e-47 160.8 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 KFY01644.1 - 6.5e-05 22.6 0.0 8.3e-05 22.3 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 KFY01644.1 - 0.0011 19.2 0.0 0.0013 19.0 0.0 1.3 1 0 0 1 1 1 1 RWD domain UEV PF05743.13 KFY01644.1 - 0.0038 17.1 0.0 0.0053 16.6 0.0 1.4 1 0 0 1 1 1 1 UEV domain Pkinase PF00069.25 KFY01645.1 - 7.9e-60 202.4 0.0 1e-59 202.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFY01645.1 - 2.6e-25 89.2 0.0 3.6e-25 88.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KFY01645.1 - 2.1e-07 30.5 0.0 2.9e-07 30.1 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 KFY01645.1 - 0.0049 16.8 0.0 0.87 9.5 0.0 2.3 2 0 0 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.14 KFY01645.1 - 0.018 14.4 0.0 0.032 13.6 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family F-box-like PF12937.7 KFY01646.1 - 1.1e-07 31.6 0.1 2.1e-07 30.7 0.1 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KFY01646.1 - 0.0004 20.2 0.7 0.0014 18.5 0.1 2.2 2 0 0 2 2 2 1 F-box domain RRM_1 PF00076.22 KFY01648.1 - 5.5e-14 51.7 0.2 1.7e-13 50.2 0.1 1.9 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Sacchrp_dh_NADP PF03435.18 KFY01648.1 - 7.8e-14 52.0 0.0 1.8e-13 50.9 0.0 1.6 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Semialdhyde_dh PF01118.24 KFY01648.1 - 0.026 15.0 0.1 12 6.4 0.0 2.6 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain SCO1-SenC PF02630.14 KFY01648.1 - 0.1 12.5 0.0 0.2 11.6 0.0 1.4 1 0 0 1 1 1 0 SCO1/SenC eIF-5a PF01287.20 KFY01653.1 - 5.5e-13 48.8 0.4 1e-12 48.0 0.4 1.5 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold EFP_N PF08207.12 KFY01653.1 - 0.058 13.4 0.0 0.12 12.4 0.0 1.5 1 0 0 1 1 1 0 Elongation factor P (EF-P) KOW-like domain Vps52 PF04129.12 KFY01654.1 - 2.4e-119 399.4 0.4 4.9e-119 398.4 0.4 1.5 1 0 0 1 1 1 1 Vps52 / Sac2 family Ank_2 PF12796.7 KFY01654.1 - 3.2e-11 43.7 0.1 2.3e-05 24.9 0.0 6.0 3 1 3 6 6 6 1 Ankyrin repeats (3 copies) NACHT PF05729.12 KFY01654.1 - 1e-05 25.5 0.1 4.7e-05 23.4 0.0 2.3 2 1 0 2 2 1 1 NACHT domain Ank_3 PF13606.6 KFY01654.1 - 8.7e-05 22.7 0.2 0.42 11.3 0.0 6.1 6 0 0 6 6 4 1 Ankyrin repeat AAA_16 PF13191.6 KFY01654.1 - 0.00029 21.2 1.4 0.0012 19.3 0.0 2.7 3 0 0 3 3 2 1 AAA ATPase domain Ank PF00023.30 KFY01654.1 - 0.00038 20.8 0.0 0.77 10.3 0.0 5.1 5 1 0 5 5 5 1 Ankyrin repeat AAA_22 PF13401.6 KFY01654.1 - 0.0022 18.3 0.0 0.0077 16.5 0.0 1.9 1 0 0 1 1 1 1 AAA domain Ank_4 PF13637.6 KFY01654.1 - 0.0045 17.5 0.0 0.11 13.1 0.0 3.4 2 1 1 3 3 3 1 Ankyrin repeats (many copies) AAA_19 PF13245.6 KFY01654.1 - 0.0062 16.9 0.1 0.13 12.6 0.0 2.8 2 1 0 2 2 2 1 AAA domain Ank_5 PF13857.6 KFY01654.1 - 0.0083 16.4 0.0 15 6.1 0.0 3.8 2 1 1 3 3 3 0 Ankyrin repeats (many copies) Sec3_C PF09763.9 KFY01654.1 - 0.0098 14.3 0.2 0.019 13.4 0.2 1.4 1 0 0 1 1 1 1 Exocyst complex component Sec3 DpaA_N PF16924.5 KFY01654.1 - 0.035 14.2 0.0 0.15 12.1 0.0 2.1 1 0 0 1 1 1 0 Dipicolinate synthase subunit A N-terminal domain DUF4349 PF14257.6 KFY01654.1 - 0.038 13.5 0.7 5.1 6.5 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4349) SesA PF17107.5 KFY01654.1 - 0.043 14.0 2.5 0.16 12.2 0.4 3.0 3 0 0 3 3 2 0 N-terminal domain on NACHT_NTPase and P-loop NTPases NB-ARC PF00931.22 KFY01654.1 - 0.052 12.7 0.0 0.12 11.6 0.0 1.6 1 0 0 1 1 1 0 NB-ARC domain DUF1664 PF07889.12 KFY01654.1 - 0.11 12.6 5.4 13 5.8 0.1 4.1 4 0 0 4 4 4 0 Protein of unknown function (DUF1664) Carn_acyltransf PF00755.20 KFY01655.1 - 1e-202 674.9 0.0 1.2e-202 674.7 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase Eaf7 PF07904.13 KFY01655.1 - 3.3e-25 88.5 0.1 8e-25 87.3 0.1 1.7 1 0 0 1 1 1 1 Chromatin modification-related protein EAF7 CDC27 PF09507.10 KFY01655.1 - 0.28 10.5 6.7 0.45 9.8 6.7 1.2 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 FoP_duplication PF13865.6 KFY01655.1 - 0.76 10.4 22.5 0.7 10.5 6.1 2.9 2 0 0 2 2 2 0 C-terminal duplication domain of Friend of PRMT1 FeS_assembly_P PF01883.19 KFY01657.1 - 6.5e-09 35.8 0.1 3.1e-08 33.6 0.1 2.1 1 1 0 1 1 1 1 Iron-sulfur cluster assembly protein DHHC PF01529.20 KFY01658.1 - 1.4e-29 102.9 7.8 1.4e-29 102.9 7.8 1.6 2 0 0 2 2 2 1 DHHC palmitoyltransferase NTF2 PF02136.20 KFY01667.1 - 5.9e-24 84.9 0.1 9.7e-24 84.2 0.1 1.4 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain Dicty_CAR PF05462.11 KFY01668.1 - 3e-17 62.7 8.4 4.9e-17 62.0 8.4 1.2 1 0 0 1 1 1 1 Slime mold cyclic AMP receptor 7tm_1 PF00001.21 KFY01668.1 - 2.9e-09 36.6 0.2 4.5e-09 36.0 0.2 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7tm_2 PF00002.24 KFY01668.1 - 3.5e-09 36.3 9.3 5.7e-09 35.6 9.3 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) Git3 PF11710.8 KFY01668.1 - 6.8e-06 26.0 11.3 1.2e-05 25.2 11.3 1.3 1 0 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 Frizzled PF01534.17 KFY01668.1 - 0.0058 15.7 11.3 2.6 7.0 11.3 2.2 1 1 0 1 1 1 1 Frizzled/Smoothened family membrane region SAP PF02037.27 KFY01669.1 - 2.5e-13 49.4 0.0 4.5e-13 48.6 0.0 1.4 1 0 0 1 1 1 1 SAP domain HeH PF12949.7 KFY01669.1 - 0.0035 17.0 0.2 0.011 15.5 0.2 1.9 1 1 0 1 1 1 1 HeH/LEM domain Tho1_MOS11_C PF18592.1 KFY01669.1 - 0.037 13.8 9.1 4.7 7.1 0.3 2.8 2 1 0 2 2 2 0 Tho1/MOS11 C-terminal domain RR_TM4-6 PF06459.12 KFY01669.1 - 0.58 9.9 7.2 1.1 9.0 7.2 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Methyltransf_11 PF08241.12 KFY01671.1 - 0.13 12.9 0.0 0.26 11.9 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Sugar_tr PF00083.24 KFY01672.1 - 3.8e-115 385.3 21.5 4.3e-115 385.1 21.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KFY01672.1 - 1.7e-22 79.9 29.4 1.7e-22 79.9 29.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF4457 PF14652.6 KFY01672.1 - 0.13 11.5 0.0 0.2 10.9 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4457) DUF2264 PF10022.9 KFY01673.1 - 1.6e-133 445.2 0.0 1.9e-133 444.9 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2264) DNA_primase_lrg PF04104.14 KFY01674.1 - 3.6e-09 36.4 0.0 5.9e-09 35.7 0.0 1.3 1 0 0 1 1 1 1 Eukaryotic and archaeal DNA primase, large subunit Zn_clus PF00172.18 KFY01677.1 - 2.1e-05 24.5 9.3 4.7e-05 23.4 9.3 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain AlaDh_PNT_N PF05222.15 KFY01681.1 - 5.1e-20 72.2 0.0 8e-20 71.5 0.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, N-terminal domain AlaDh_PNT_C PF01262.21 KFY01681.1 - 0.022 14.0 0.0 0.093 12.0 0.0 1.8 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain DUF973 PF06157.11 KFY01681.1 - 0.031 13.3 0.2 0.051 12.6 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF973) Cys_Met_Meta_PP PF01053.20 KFY01682.1 - 3.7e-123 410.9 0.0 4.4e-123 410.6 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.19 KFY01682.1 - 1.6e-05 24.1 0.0 2.9e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.21 KFY01682.1 - 0.00085 18.6 0.0 0.0013 17.9 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.17 KFY01682.1 - 0.014 14.8 0.7 0.12 11.7 0.7 2.1 1 1 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family Ydc2-catalyt PF09159.10 KFY01684.1 - 5.4e-67 226.5 0.0 6.6e-67 226.2 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial resolvase Ydc2 / RNA splicing MRS1 Pox_A22 PF04848.13 KFY01684.1 - 0.0012 19.0 0.1 1.5 8.9 0.1 3.1 2 1 0 2 2 2 2 Poxvirus A22 protein Herpes_UL49_5 PF05702.11 KFY01685.1 - 0.043 13.9 0.2 0.085 12.9 0.2 1.6 1 1 0 1 1 1 0 Herpesvirus UL49.5 envelope/tegument protein AF-4 PF05110.13 KFY01685.1 - 6.9 4.6 9.8 7.7 4.5 9.8 1.0 1 0 0 1 1 1 0 AF-4 proto-oncoprotein Septin PF00735.18 KFY01686.1 - 6e-112 373.5 0.3 7.1e-112 373.3 0.3 1.0 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.23 KFY01686.1 - 7.2e-08 32.5 0.0 1.7e-07 31.3 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase AIG1 PF04548.16 KFY01686.1 - 5e-06 26.0 0.0 8.6e-06 25.2 0.0 1.4 1 0 0 1 1 1 1 AIG1 family RsgA_GTPase PF03193.16 KFY01686.1 - 3.6e-05 23.7 0.2 0.00028 20.8 0.0 2.1 2 0 0 2 2 2 1 RsgA GTPase GTP_EFTU PF00009.27 KFY01686.1 - 0.00022 20.8 0.6 0.016 14.7 0.1 2.4 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain Dynamin_N PF00350.23 KFY01686.1 - 0.00049 20.2 0.3 1.5 8.9 0.0 2.5 1 1 0 2 2 2 2 Dynamin family AAA_16 PF13191.6 KFY01686.1 - 0.0022 18.4 0.1 0.0085 16.5 0.1 2.1 1 1 0 1 1 1 1 AAA ATPase domain AAA_7 PF12775.7 KFY01686.1 - 0.0066 16.0 0.0 0.034 13.7 0.0 2.1 2 0 0 2 2 2 1 P-loop containing dynein motor region NB-ARC PF00931.22 KFY01686.1 - 0.0077 15.5 0.1 0.014 14.6 0.1 1.3 1 0 0 1 1 1 1 NB-ARC domain AAA_22 PF13401.6 KFY01686.1 - 0.0092 16.3 0.0 0.018 15.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.27 KFY01686.1 - 0.013 16.0 0.2 0.024 15.1 0.2 1.7 1 1 0 1 1 1 0 ABC transporter AAA_23 PF13476.6 KFY01686.1 - 0.044 14.3 0.1 0.095 13.2 0.1 1.5 1 1 0 1 1 1 0 AAA domain G-alpha PF00503.20 KFY01686.1 - 0.046 12.9 0.5 0.14 11.3 0.5 1.9 1 1 0 1 1 1 0 G-protein alpha subunit Gtr1_RagA PF04670.12 KFY01686.1 - 0.061 12.7 0.1 0.65 9.3 0.0 2.1 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region FtsK_SpoIIIE PF01580.18 KFY01686.1 - 0.073 12.4 0.0 0.13 11.6 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family T2SSE PF00437.20 KFY01686.1 - 0.093 11.8 0.0 0.23 10.5 0.0 1.6 2 0 0 2 2 2 0 Type II/IV secretion system protein Roc PF08477.13 KFY01686.1 - 0.11 12.7 0.0 0.23 11.7 0.0 1.5 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase AAA_29 PF13555.6 KFY01686.1 - 0.2 11.5 0.0 0.41 10.4 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Ribosomal_L32p PF01783.23 KFY01687.1 - 9.9e-14 51.3 2.1 9.9e-14 51.3 2.1 1.5 2 0 0 2 2 2 1 Ribosomal L32p protein family zf-ribbon_3 PF13248.6 KFY01687.1 - 0.0036 16.7 1.0 0.006 16.0 1.0 1.3 1 0 0 1 1 1 1 zinc-ribbon domain zinc-ribbons_6 PF07191.12 KFY01687.1 - 0.012 15.5 0.3 0.018 15.0 0.3 1.2 1 0 0 1 1 1 0 zinc-ribbons WD40 PF00400.32 KFY01688.1 - 2.7e-23 81.8 7.2 3.9e-06 27.5 0.2 7.0 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFY01688.1 - 6.6e-14 52.0 0.5 0.0025 18.1 0.0 4.4 1 1 3 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain Cytochrom_D1 PF02239.16 KFY01688.1 - 2.2e-07 29.7 0.3 2e-06 26.6 0.3 1.9 1 1 0 1 1 1 1 Cytochrome D1 heme domain Nbas_N PF15492.6 KFY01688.1 - 5.1e-05 22.7 0.5 0.074 12.4 0.0 3.5 1 1 2 4 4 4 2 Neuroblastoma-amplified sequence, N terminal eIF2A PF08662.11 KFY01688.1 - 0.00017 21.5 0.0 0.022 14.6 0.0 3.0 2 1 2 4 4 4 2 Eukaryotic translation initiation factor eIF2A Coatomer_WDAD PF04053.14 KFY01688.1 - 0.011 14.9 0.0 0.042 12.9 0.0 1.5 1 1 1 2 2 2 0 Coatomer WD associated region WD40_like PF17005.5 KFY01688.1 - 0.011 15.1 0.0 1.6 8.0 0.0 2.5 2 1 1 3 3 3 0 WD40-like domain Ge1_WD40 PF16529.5 KFY01688.1 - 0.032 13.2 0.1 3.1 6.7 0.0 3.0 2 2 0 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein PALB2_WD40 PF16756.5 KFY01688.1 - 0.059 12.3 0.1 0.46 9.3 0.1 2.1 2 0 0 2 2 2 0 Partner and localizer of BRCA2 WD40 domain VID27 PF08553.10 KFY01688.1 - 0.13 11.3 0.0 0.38 9.7 0.0 1.6 1 1 1 2 2 2 0 VID27 C-terminal WD40-like domain PPR_2 PF13041.6 KFY01689.1 - 1.5e-16 60.3 2.8 0.00049 20.2 0.0 5.2 3 2 2 5 5 5 4 PPR repeat family PPR PF01535.20 KFY01689.1 - 4.4e-11 42.2 4.2 8.3e-05 22.6 0.0 5.3 5 0 0 5 5 5 2 PPR repeat PPR_3 PF13812.6 KFY01689.1 - 7.4e-06 25.9 0.9 0.0043 17.1 0.0 3.0 3 0 0 3 3 3 2 Pentatricopeptide repeat domain PPR_1 PF12854.7 KFY01689.1 - 0.00029 20.5 2.1 0.019 14.7 0.0 3.6 3 0 0 3 3 3 1 PPR repeat PPR_long PF17177.4 KFY01689.1 - 0.0024 17.3 0.6 0.0078 15.6 0.2 1.9 2 0 0 2 2 2 1 Pentacotripeptide-repeat region of PRORP MRP-S25 PF13741.6 KFY01690.1 - 2.8e-73 246.3 8.0 8.5e-71 238.2 8.0 2.1 1 1 0 1 1 1 1 Mitochondrial ribosomal protein S25 MRP-S23 PF10484.9 KFY01690.1 - 0.031 14.5 1.4 0.11 12.8 0.9 2.3 1 1 1 2 2 2 0 Mitochondrial ribosomal protein S23 SOG2 PF10428.9 KFY01691.1 - 6.1e-78 263.2 9.4 1.5e-51 176.2 0.6 4.5 4 1 1 5 5 5 2 RAM signalling pathway protein LRR_8 PF13855.6 KFY01691.1 - 5.8e-17 61.2 1.8 1.5e-08 34.2 0.3 3.1 3 0 0 3 3 3 2 Leucine rich repeat LRR_4 PF12799.7 KFY01691.1 - 4.5e-15 55.5 2.7 2.5e-05 24.5 0.0 3.7 1 1 1 3 3 3 3 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 KFY01691.1 - 0.0011 18.9 4.5 6.8 7.0 0.1 4.8 5 0 0 5 5 5 1 Leucine Rich repeat LRR_1 PF00560.33 KFY01691.1 - 0.0071 16.7 6.4 4.4 8.2 0.1 5.1 5 0 0 5 5 5 1 Leucine Rich Repeat HemN_C PF06969.16 KFY01691.1 - 0.027 14.5 0.1 0.47 10.6 0.0 2.7 2 1 0 2 2 2 0 HemN C-terminal domain GTP_EFTU PF00009.27 KFY01699.1 - 3.8e-49 166.9 0.0 5.6e-49 166.3 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain HBS1_N PF08938.10 KFY01699.1 - 1.4e-25 89.4 0.7 3e-25 88.3 0.7 1.5 1 0 0 1 1 1 1 HBS1 N-terminus GTP_EFTU_D3 PF03143.17 KFY01699.1 - 1.5e-09 38.2 0.0 5.1e-09 36.4 0.0 1.9 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain MMR_HSR1 PF01926.23 KFY01699.1 - 1.4e-08 34.8 0.0 0.00012 22.2 0.0 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase GTP_EFTU_D2 PF03144.25 KFY01699.1 - 1.2e-07 32.0 0.0 3.3e-07 30.6 0.0 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 Roc PF08477.13 KFY01699.1 - 0.0035 17.6 0.0 0.36 11.1 0.0 2.4 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 KFY01699.1 - 0.036 13.5 0.0 2.4 7.6 0.0 2.4 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit Septin PF00735.18 KFY01699.1 - 0.17 11.2 0.0 0.31 10.3 0.0 1.3 1 0 0 1 1 1 0 Septin HSP70 PF00012.20 KFY01700.1 - 3.4e-262 871.0 13.0 3.9e-262 870.8 13.0 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 KFY01700.1 - 2.3e-16 59.5 1.8 4.7e-15 55.2 0.1 2.1 1 1 1 2 2 2 2 MreB/Mbl protein FtsA PF14450.6 KFY01700.1 - 0.006 17.0 5.2 4.5 7.7 0.4 3.7 3 1 0 3 3 3 2 Cell division protein FtsA Radial_spoke_3 PF06098.11 KFY01700.1 - 0.18 11.1 5.1 0.031 13.6 1.4 1.6 2 0 0 2 2 2 0 Radial spoke protein 3 HEPPP_synt_1 PF07307.11 KFY01700.1 - 0.22 11.1 1.4 0.45 10.1 1.4 1.5 1 0 0 1 1 1 0 Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1 Hydantoinase_A PF01968.18 KFY01700.1 - 0.26 10.5 0.1 0.26 10.5 0.1 2.3 2 1 0 3 3 3 0 Hydantoinase/oxoprolinase SelR PF01641.18 KFY01701.1 - 1e-48 164.4 0.1 1.7e-48 163.7 0.1 1.3 1 0 0 1 1 1 1 SelR domain DZR PF12773.7 KFY01701.1 - 0.01 15.8 0.6 0.61 10.2 0.1 2.3 2 0 0 2 2 2 0 Double zinc ribbon zinc_ribbon_10 PF10058.9 KFY01701.1 - 0.015 15.0 0.2 0.6 9.9 0.0 2.2 2 0 0 2 2 2 0 Predicted integral membrane zinc-ribbon metal-binding protein Tnp_zf-ribbon_2 PF13842.6 KFY01701.1 - 0.037 14.8 0.2 12 6.8 0.0 2.5 2 0 0 2 2 2 0 DDE_Tnp_1-like zinc-ribbon Yippee-Mis18 PF03226.14 KFY01701.1 - 0.086 13.1 0.4 0.26 11.5 0.4 1.8 1 1 0 1 1 1 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly TF_Zn_Ribbon PF08271.12 KFY01701.1 - 0.13 11.8 1.1 4.9 6.8 0.2 2.4 2 0 0 2 2 2 0 TFIIB zinc-binding Synaptobrevin PF00957.21 KFY01702.1 - 0.075 12.8 0.2 4 7.3 0.0 2.0 1 1 1 2 2 2 0 Synaptobrevin Ysc84 PF04366.12 KFY01703.1 - 1.9e-42 144.0 0.4 3.3e-42 143.3 0.4 1.4 1 0 0 1 1 1 1 Las17-binding protein actin regulator SH3_1 PF00018.28 KFY01703.1 - 1.9e-14 53.0 0.2 9.5e-14 50.7 0.1 2.1 2 0 0 2 2 2 1 SH3 domain SH3_2 PF07653.17 KFY01703.1 - 3.9e-14 52.1 0.1 1.8e-13 49.9 0.0 2.1 2 0 0 2 2 2 1 Variant SH3 domain SH3_9 PF14604.6 KFY01703.1 - 1.1e-12 47.6 0.0 2.2e-12 46.6 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain DUF3176 PF11374.8 KFY01705.1 - 0.071 13.3 1.2 0.24 11.6 1.2 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3176) EMC3_TMCO1 PF01956.16 KFY01705.1 - 3.3 7.4 5.3 4.3 7.0 0.1 2.4 2 0 0 2 2 2 0 Integral membrane protein EMC3/TMCO1-like AA_permease_2 PF13520.6 KFY01706.1 - 3.6e-43 148.0 56.4 6.6e-43 147.1 56.4 1.4 1 1 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KFY01706.1 - 1.6e-19 69.9 46.4 2.3e-19 69.4 46.4 1.1 1 0 0 1 1 1 1 Amino acid permease Ras PF00071.22 KFY01707.1 - 5.4e-44 149.6 0.0 7.1e-44 149.3 0.0 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFY01707.1 - 1.7e-20 73.4 0.0 2.6e-20 72.8 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFY01707.1 - 3.3e-05 23.4 0.0 5.2e-05 22.8 0.0 1.4 1 1 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 KFY01707.1 - 0.026 14.0 0.0 0.038 13.4 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_7 PF12775.7 KFY01707.1 - 0.07 12.6 0.0 0.11 11.9 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region PAP2 PF01569.21 KFY01708.1 - 4e-16 59.0 2.4 1e-15 57.7 2.4 1.7 1 0 0 1 1 1 1 PAP2 superfamily PAP2_3 PF14378.6 KFY01708.1 - 0.091 12.4 9.0 0.32 10.6 9.0 2.0 1 1 0 1 1 1 0 PAP2 superfamily RabGAP-TBC PF00566.18 KFY01710.1 - 2.3e-50 171.3 0.0 4.2e-50 170.4 0.0 1.4 1 0 0 1 1 1 1 Rab-GTPase-TBC domain adh_short_C2 PF13561.6 KFY01711.1 - 5.3e-53 180.0 1.6 6.4e-53 179.7 1.6 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KFY01711.1 - 1e-44 152.3 1.0 1.4e-44 151.9 1.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KFY01711.1 - 1.1e-07 31.9 0.2 3.5e-07 30.3 0.2 1.8 1 1 0 1 1 1 1 KR domain TB PF00683.17 KFY01712.1 - 0.019 14.7 0.3 0.029 14.1 0.3 1.3 1 0 0 1 1 1 0 TB domain KxDL PF10241.9 KFY01728.1 - 0.72 10.2 8.8 3.1 8.1 2.2 2.8 2 0 0 2 2 2 0 Uncharacterized conserved protein PGPGW PF09656.10 KFY01729.1 - 0.068 12.7 0.5 0.16 11.5 0.5 1.6 1 0 0 1 1 1 0 Putative transmembrane protein (PGPGW) HSP70 PF00012.20 KFY01733.1 - 1.7e-10 39.7 0.4 1.2e-09 36.9 0.2 1.9 2 0 0 2 2 2 1 Hsp70 protein MreB_Mbl PF06723.13 KFY01733.1 - 0.022 13.6 0.1 0.18 10.6 0.0 2.0 2 0 0 2 2 2 0 MreB/Mbl protein PLA2_B PF01735.18 KFY01734.1 - 1.2e-193 644.0 6.5 1.5e-193 643.7 6.5 1.1 1 0 0 1 1 1 1 Lysophospholipase catalytic domain Ion_trans_2 PF07885.16 KFY01736.1 - 1.5e-32 111.3 17.9 2.8e-17 62.5 5.9 3.4 3 0 0 3 3 3 2 Ion channel adh_short PF00106.25 KFY01736.1 - 1e-21 77.3 0.2 2.8e-15 56.3 0.1 2.7 3 0 0 3 3 3 2 short chain dehydrogenase adh_short_C2 PF13561.6 KFY01736.1 - 4.9e-08 32.8 0.0 0.00041 20.0 0.0 2.4 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KFY01736.1 - 1.7e-06 28.1 0.5 3e-06 27.3 0.5 1.4 1 0 0 1 1 1 1 KR domain Ion_trans PF00520.31 KFY01736.1 - 0.0016 17.7 1.4 0.0016 17.7 1.4 3.1 3 0 0 3 3 3 2 Ion transport protein Phage_holin_4_2 PF04020.13 KFY01736.1 - 0.0082 16.8 8.2 0.039 14.6 1.4 3.5 3 0 0 3 3 3 1 Mycobacterial 4 TMS phage holin, superfamily IV DUF2976 PF11190.8 KFY01736.1 - 4.9 7.0 6.5 2.5 8.0 0.1 3.2 4 0 0 4 4 4 0 Protein of unknown function (DUF2976) DUF488 PF04343.13 KFY01741.1 - 3e-18 66.5 0.0 4.6e-18 66.0 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF488 SPX PF03105.19 KFY01742.1 - 1.1e-41 144.1 12.0 2.9e-28 99.9 0.1 3.1 2 1 1 3 3 3 3 SPX domain Na_sulph_symp PF00939.19 KFY01742.1 - 2.7e-32 112.5 45.9 4.2e-32 111.8 45.9 1.2 1 0 0 1 1 1 1 Sodium:sulfate symporter transmembrane region CitMHS PF03600.16 KFY01742.1 - 1.1e-24 87.1 73.1 5.4e-22 78.3 45.1 2.9 1 1 2 3 3 3 2 Citrate transporter DUF4611 PF15387.6 KFY01742.1 - 9.2 6.6 12.0 6.8 7.0 2.4 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4611) Diphthamide_syn PF01866.17 KFY01743.1 - 1.2e-117 392.7 0.0 1.6e-117 392.3 0.0 1.1 1 0 0 1 1 1 1 Putative diphthamide synthesis protein ATP-synt_ab PF00006.25 KFY01744.1 - 3.2e-66 223.0 0.0 4.9e-66 222.4 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain HMGL-like PF00682.19 KFY01744.1 - 4.5e-46 157.6 0.0 6.3e-46 157.1 0.0 1.2 1 0 0 1 1 1 1 HMGL-like ATP-synt_ab_N PF02874.23 KFY01744.1 - 3.4e-13 49.9 0.9 3.4e-13 49.9 0.9 2.2 2 0 0 2 2 2 1 ATP synthase alpha/beta family, beta-barrel domain DUF5535 PF17687.1 KFY01744.1 - 0.11 12.7 0.0 0.26 11.5 0.0 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5535) Aminotran_3 PF00202.21 KFY01745.1 - 9.9e-111 370.3 0.0 1.3e-110 369.8 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III Steroid_dh PF02544.16 KFY01746.1 - 4.6e-24 85.1 0.6 6.4e-24 84.7 0.6 1.2 1 0 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase PEMT PF04191.13 KFY01746.1 - 0.046 14.1 1.6 0.064 13.7 0.3 1.9 2 0 0 2 2 2 0 Phospholipid methyltransferase DUF1295 PF06966.12 KFY01746.1 - 0.14 11.7 3.8 0.2 11.1 3.3 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1295) Strabismus PF06638.11 KFY01746.1 - 0.19 10.4 0.3 0.2 10.3 0.3 1.1 1 0 0 1 1 1 0 Strabismus protein RabGAP-TBC PF00566.18 KFY01747.1 - 1.7e-48 165.1 0.2 3.6e-47 160.8 0.2 2.3 1 1 0 1 1 1 1 Rab-GTPase-TBC domain Cnn_1N PF07989.11 KFY01747.1 - 0.0067 16.6 3.4 0.0067 16.6 3.4 3.0 1 1 1 2 2 2 2 Centrosomin N-terminal motif 1 Filament PF00038.21 KFY01747.1 - 0.067 12.8 18.9 0.039 13.6 9.1 2.3 1 1 1 2 2 2 0 Intermediate filament protein YabA PF06156.13 KFY01747.1 - 0.98 10.1 14.0 12 6.6 6.5 2.9 1 1 1 2 2 2 0 Initiation control protein YabA Mod_r PF07200.13 KFY01747.1 - 1.8 8.6 18.1 2.8 8.0 8.5 3.2 1 1 2 3 3 3 0 Modifier of rudimentary (Mod(r)) protein HALZ PF02183.18 KFY01747.1 - 3.8 7.8 12.5 0.36 11.1 0.7 3.6 4 0 0 4 4 4 0 Homeobox associated leucine zipper FlaC_arch PF05377.11 KFY01747.1 - 10 6.6 9.9 91 3.6 1.6 3.9 2 2 2 4 4 4 0 Flagella accessory protein C (FlaC) F-box PF00646.33 KFY01755.1 - 2.8e-05 23.9 0.0 2.8e-05 23.9 0.0 2.3 3 0 0 3 3 3 1 F-box domain F-box-like PF12937.7 KFY01755.1 - 4.6e-05 23.2 0.3 0.00025 20.9 0.1 2.1 2 0 0 2 2 2 1 F-box-like DUF4524 PF15025.6 KFY01755.1 - 0.029 14.1 0.0 0.041 13.6 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4524) zf-CHY PF05495.12 KFY01755.1 - 0.48 10.9 6.1 5.5 7.6 1.6 2.8 1 1 0 2 2 2 0 CHY zinc finger PHD_2 PF13831.6 KFY01755.1 - 1.8 8.2 8.6 12 5.6 0.0 3.6 4 0 0 4 4 4 0 PHD-finger Aldedh PF00171.22 KFY01756.1 - 3.4e-153 510.5 1.0 4.1e-153 510.2 1.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.11 KFY01756.1 - 0.012 15.1 0.0 0.048 13.1 0.0 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1487) OmdA PF13376.6 KFY01756.1 - 0.11 12.5 0.5 0.26 11.3 0.5 1.6 1 0 0 1 1 1 0 Bacteriocin-protection, YdeI or OmpD-Associated RTP1_C1 PF10363.9 KFY01757.1 - 6.3e-26 90.8 0.0 3e-25 88.6 0.0 2.3 2 0 0 2 2 2 1 Required for nuclear transport of RNA pol II C-terminus 1 RTP1_C2 PF10304.9 KFY01757.1 - 1.1e-06 28.2 0.2 3e-06 26.8 0.2 1.7 1 0 0 1 1 1 1 Required for nuclear transport of RNA pol II C-terminus 2 DASH_Dad3 PF08656.10 KFY01758.1 - 3.1e-31 107.3 0.5 4.2e-31 106.9 0.5 1.2 1 0 0 1 1 1 1 DASH complex subunit Dad3 Ribosomal_S5_C PF03719.15 KFY01759.1 - 2.8e-21 74.7 0.0 5.9e-21 73.7 0.0 1.6 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain Ribosomal_S5 PF00333.20 KFY01759.1 - 2.2e-18 66.0 0.3 4.4e-18 65.0 0.3 1.5 1 0 0 1 1 1 1 Ribosomal protein S5, N-terminal domain tRNA_U5-meth_tr PF05958.11 KFY01760.1 - 3.3e-11 42.8 0.0 1.7e-09 37.1 0.0 2.9 2 1 0 2 2 2 1 tRNA (Uracil-5-)-methyltransferase Methyltransf_15 PF09445.10 KFY01760.1 - 3.3e-06 26.8 0.0 5.5e-06 26.0 0.0 1.3 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Methyltransf_25 PF13649.6 KFY01760.1 - 0.00039 21.1 0.0 0.00095 19.8 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 KFY01760.1 - 0.003 17.0 0.0 0.0045 16.4 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_31 PF13847.6 KFY01760.1 - 0.015 15.1 0.0 0.03 14.1 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Cons_hypoth95 PF03602.15 KFY01760.1 - 0.031 13.9 0.0 0.052 13.2 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical protein 95 UNC45-central PF11701.8 KFY01761.1 - 1.9e-52 177.3 0.2 4.3e-49 166.4 0.0 4.1 4 0 0 4 4 4 2 Myosin-binding striated muscle assembly central Arm PF00514.23 KFY01761.1 - 0.0012 18.8 20.5 0.31 11.2 0.0 8.2 8 1 0 8 8 8 2 Armadillo/beta-catenin-like repeat IFRD PF05004.13 KFY01761.1 - 0.19 10.8 2.8 7.3 5.6 0.2 3.2 4 0 0 4 4 4 0 Interferon-related developmental regulator (IFRD) HEAT_2 PF13646.6 KFY01761.1 - 0.44 11.0 18.4 1.8 9.0 2.7 5.3 4 3 1 6 6 6 0 HEAT repeats HEAT_EZ PF13513.6 KFY01761.1 - 7.4 7.2 13.1 21 5.8 0.2 6.0 7 0 0 7 7 7 0 HEAT-like repeat Tfb4 PF03850.14 KFY01762.1 - 4e-105 351.3 0.0 4.6e-105 351.0 0.0 1.0 1 0 0 1 1 1 1 Transcription factor Tfb4 Actin PF00022.19 KFY01764.1 - 2.9e-86 289.6 0.0 4.2e-84 282.5 0.0 2.1 1 1 0 1 1 1 1 Actin ADH_N PF08240.12 KFY01764.1 - 3.4e-29 100.9 0.7 3.4e-29 100.9 0.7 1.7 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KFY01764.1 - 3.9e-23 81.9 0.0 8e-23 80.8 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KFY01764.1 - 3.1e-05 25.0 0.1 6.3e-05 24.0 0.1 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 KFY01764.1 - 0.0085 15.5 0.1 0.015 14.7 0.1 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 KFY01764.1 - 0.019 14.3 0.4 0.031 13.6 0.4 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Glucokinase PF02685.16 KFY01764.1 - 0.12 11.3 0.5 0.24 10.3 0.5 1.4 1 0 0 1 1 1 0 Glucokinase adh_short PF00106.25 KFY01764.1 - 0.18 11.3 0.5 0.32 10.4 0.5 1.4 1 0 0 1 1 1 0 short chain dehydrogenase ACP_syn_III_C PF08541.10 KFY01764.1 - 0.63 10.3 2.0 0.63 10.3 0.1 1.9 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal Asparaginase_2 PF01112.18 KFY01765.1 - 4.6e-44 150.7 0.4 3.9e-27 95.1 0.0 2.4 2 0 0 2 2 2 2 Asparaginase GDPD PF03009.17 KFY01766.1 - 1.5e-70 237.9 0.0 2.8e-70 237.0 0.0 1.5 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family Ank_2 PF12796.7 KFY01766.1 - 1.3e-29 102.6 1.4 5.9e-10 39.6 0.1 5.0 2 1 3 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KFY01766.1 - 4.9e-25 87.6 2.3 2.9e-09 37.3 0.0 5.6 5 0 0 5 5 5 3 Ankyrin repeats (many copies) SPX PF03105.19 KFY01766.1 - 2.1e-22 80.6 4.9 2.4e-11 44.2 0.0 3.4 1 1 2 3 3 3 3 SPX domain Ank_5 PF13857.6 KFY01766.1 - 7.6e-17 61.2 0.7 1.6e-09 37.8 0.0 4.9 3 2 1 4 4 4 2 Ankyrin repeats (many copies) Ank PF00023.30 KFY01766.1 - 4e-16 58.7 1.1 0.00016 22.0 0.0 6.6 6 0 0 6 6 6 3 Ankyrin repeat Ank_3 PF13606.6 KFY01766.1 - 1.4e-14 52.7 4.2 0.0087 16.5 0.0 7.6 8 0 0 8 8 8 3 Ankyrin repeat TelA PF05816.11 KFY01766.1 - 0.1 11.7 0.2 0.19 10.7 0.2 1.4 1 0 0 1 1 1 0 Toxic anion resistance protein (TelA) RicinB_lectin_2 PF14200.6 KFY01767.1 - 0.00012 22.7 2.6 0.18 12.5 0.2 3.0 1 1 1 2 2 2 2 Ricin-type beta-trefoil lectin domain-like Mucin PF01456.17 KFY01767.1 - 0.023 14.7 4.5 0.023 14.7 4.5 1.9 2 0 0 2 2 2 0 Mucin-like glycoprotein PPR_3 PF13812.6 KFY01768.1 - 4e-05 23.6 0.1 0.0013 18.7 0.0 2.3 2 0 0 2 2 2 1 Pentatricopeptide repeat domain PPR_long PF17177.4 KFY01768.1 - 0.00018 21.0 0.1 0.019 14.3 0.0 2.4 2 0 0 2 2 2 2 Pentacotripeptide-repeat region of PRORP PPR_2 PF13041.6 KFY01768.1 - 0.024 14.8 0.2 0.38 11.0 0.0 2.6 3 0 0 3 3 3 0 PPR repeat family DUF866 PF05907.13 KFY01769.1 - 3.5e-62 208.9 0.3 6.5e-62 208.0 0.0 1.5 2 0 0 2 2 2 1 Eukaryotic protein of unknown function (DUF866) LSM PF01423.22 KFY01769.1 - 3.5e-19 68.3 0.1 5e-19 67.7 0.1 1.3 1 0 0 1 1 1 1 LSM domain Basic PF01586.16 KFY01769.1 - 0.32 12.2 1.8 0.55 11.4 0.5 2.0 2 0 0 2 2 2 0 Myogenic Basic domain PRMT5_TIM PF17285.2 KFY01770.1 - 3.6e-75 252.5 0.0 4.7e-75 252.1 0.0 1.1 1 0 0 1 1 1 1 PRMT5 TIM barrel domain PRMT5 PF05185.16 KFY01770.1 - 6.8e-69 231.2 0.0 1.1e-68 230.5 0.0 1.3 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase PRMT5_C PF17286.2 KFY01770.1 - 6.2e-57 192.3 0.0 1.1e-56 191.5 0.0 1.4 1 0 0 1 1 1 1 PRMT5 oligomerisation domain AMP-binding PF00501.28 KFY01771.1 - 2e-76 257.3 0.0 2.8e-76 256.8 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme Condensation PF00668.20 KFY01771.1 - 3e-59 200.9 0.2 2e-57 194.9 0.2 2.2 1 1 0 1 1 1 1 Condensation domain PS-DH PF14765.6 KFY01771.1 - 7.3e-56 189.6 0.0 1.1e-55 189.0 0.0 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase KR PF08659.10 KFY01771.1 - 1.3e-50 171.8 0.2 3.2e-50 170.6 0.2 1.7 1 0 0 1 1 1 1 KR domain Methyltransf_12 PF08242.12 KFY01771.1 - 3.3e-21 75.9 0.0 1.2e-20 74.1 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain NAD_binding_4 PF07993.12 KFY01771.1 - 1.2e-19 70.4 0.0 6.2e-18 64.9 0.0 3.0 2 1 0 2 2 2 1 Male sterility protein PP-binding PF00550.25 KFY01771.1 - 2.2e-16 60.0 1.8 9.3e-07 29.1 0.1 3.1 2 0 0 2 2 2 2 Phosphopantetheine attachment site Methyltransf_25 PF13649.6 KFY01771.1 - 6.9e-14 52.3 0.0 2.2e-13 50.7 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KFY01771.1 - 9.5e-14 51.6 0.0 1.8e-13 50.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KFY01771.1 - 3.2e-13 50.1 0.0 1.6e-12 47.9 0.0 2.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KFY01771.1 - 6.7e-13 48.7 0.0 1.6e-12 47.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain adh_short PF00106.25 KFY01771.1 - 4.4e-07 29.6 0.1 3.5e-06 26.6 0.1 2.4 2 0 0 2 2 2 1 short chain dehydrogenase Ubie_methyltran PF01209.18 KFY01771.1 - 5e-07 29.3 0.0 1.2e-06 28.0 0.0 1.6 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Epimerase PF01370.21 KFY01771.1 - 8.1e-07 28.7 0.0 9.7e-06 25.2 0.0 2.5 3 0 0 3 3 3 1 NAD dependent epimerase/dehydratase family Methyltransf_16 PF10294.9 KFY01771.1 - 5.3e-06 26.3 0.0 1.3e-05 25.0 0.0 1.6 1 0 0 1 1 1 1 Lysine methyltransferase adh_short_C2 PF13561.6 KFY01771.1 - 1.7e-05 24.5 0.1 0.0044 16.6 0.0 2.4 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase AMP-binding_C PF13193.6 KFY01771.1 - 0.00038 21.4 0.0 0.0012 19.7 0.0 2.0 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain 3Beta_HSD PF01073.19 KFY01771.1 - 0.0011 18.1 0.0 1.4 7.8 0.0 2.4 2 0 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family DREV PF05219.12 KFY01771.1 - 0.0038 16.4 0.1 0.0081 15.3 0.1 1.5 1 0 0 1 1 1 1 DREV methyltransferase RrnaAD PF00398.20 KFY01771.1 - 0.0042 16.2 0.0 0.0091 15.1 0.0 1.5 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase MTS PF05175.14 KFY01771.1 - 0.031 13.8 0.0 0.099 12.2 0.0 1.8 2 0 0 2 2 1 0 Methyltransferase small domain Methyltransf_33 PF10017.9 KFY01771.1 - 0.039 13.1 0.0 0.086 12.0 0.0 1.5 1 0 0 1 1 1 0 Histidine-specific methyltransferase, SAM-dependent Sugar_tr PF00083.24 KFY01772.1 - 3.8e-27 95.2 24.9 8.7e-16 57.8 6.2 2.1 1 1 0 2 2 2 2 Sugar (and other) transporter DUF3611 PF12263.8 KFY01772.1 - 0.41 10.5 7.2 0.065 13.1 1.5 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF3611) PBD PF00786.28 KFY01773.1 - 0.00082 19.7 0.0 0.0016 18.8 0.0 1.5 1 0 0 1 1 1 1 P21-Rho-binding domain Isy1 PF06246.12 KFY01785.1 - 1.4e-81 273.8 0.4 1.4e-81 273.8 0.4 1.9 2 0 0 2 2 2 1 Isy1-like splicing family Metallophos PF00149.28 KFY01785.1 - 1.3e-11 45.4 0.1 2.8e-11 44.3 0.0 1.5 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 KFY01785.1 - 3e-06 27.5 0.8 7.1e-06 26.3 0.5 1.9 2 1 0 2 2 2 1 Calcineurin-like phosphoesterase superfamily domain DUF3826 PF12875.7 KFY01785.1 - 0.21 11.7 1.5 0.45 10.6 1.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3826) MMR_HSR1 PF01926.23 KFY01786.1 - 3.2e-13 49.8 0.0 6.6e-13 48.8 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KFY01786.1 - 0.00077 19.4 0.1 0.0025 17.8 0.1 1.8 1 1 0 1 1 1 1 RsgA GTPase FeoB_N PF02421.18 KFY01786.1 - 0.00097 18.7 0.0 0.0016 17.9 0.0 1.3 1 0 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.23 KFY01786.1 - 0.014 15.5 0.3 1.2 9.2 0.1 2.5 1 1 1 2 2 2 0 Dynamin family AAA_22 PF13401.6 KFY01786.1 - 0.089 13.1 0.0 8.7 6.6 0.0 2.4 2 0 0 2 2 2 0 AAA domain Roc PF08477.13 KFY01786.1 - 0.09 13.0 0.0 0.22 11.7 0.0 1.7 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase IIGP PF05049.13 KFY01786.1 - 0.23 10.5 0.0 0.37 9.8 0.0 1.2 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) Abhydrolase_1 PF00561.20 KFY01787.1 - 4.2e-45 154.4 0.0 1.2e-44 152.9 0.0 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Esterase PF00756.20 KFY01787.1 - 1.1e-05 25.2 0.0 1.8e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 Putative esterase zf-RING_6 PF14835.6 KFY01787.1 - 0.04 13.8 1.0 0.091 12.6 1.0 1.5 1 0 0 1 1 1 0 zf-RING of BARD1-type protein Glyco_hydro_3_C PF01915.22 KFY01788.1 - 4.7e-53 180.2 0.0 7.2e-53 179.6 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 KFY01788.1 - 7e-38 130.8 0.0 1.2e-37 130.0 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 KFY01788.1 - 6.4e-21 74.3 0.0 1.2e-20 73.4 0.0 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain PAN_2 PF08276.11 KFY01789.1 - 0.00015 21.8 0.0 0.00044 20.3 0.0 1.8 1 0 0 1 1 1 1 PAN-like domain PAN_1 PF00024.26 KFY01789.1 - 0.054 13.5 0.0 0.14 12.1 0.0 1.7 1 0 0 1 1 1 0 PAN domain Inv-AAD PF18785.1 KFY01789.1 - 0.064 13.1 0.0 0.13 12.2 0.0 1.4 1 0 0 1 1 1 0 Invertebrate-AID/APOBEC-deaminase ThiF PF00899.21 KFY01790.1 - 4.1e-44 150.8 0.0 6.4e-44 150.1 0.0 1.2 1 0 0 1 1 1 1 ThiF family Sacchrp_dh_NADP PF03435.18 KFY01790.1 - 5.2e-06 26.8 0.9 4.4e-05 23.8 0.9 2.1 1 1 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain NAD_binding_7 PF13241.6 KFY01790.1 - 8.8e-05 22.9 0.1 0.0002 21.8 0.1 1.6 1 0 0 1 1 1 1 Putative NAD(P)-binding UDPG_MGDP_dh_N PF03721.14 KFY01790.1 - 0.0013 18.3 0.0 0.011 15.3 0.0 2.2 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain TrkA_N PF02254.18 KFY01790.1 - 0.0068 16.7 0.2 0.02 15.2 0.0 1.9 2 0 0 2 2 2 1 TrkA-N domain ApbA PF02558.16 KFY01790.1 - 0.031 13.9 0.1 0.051 13.2 0.1 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Pyr_redox_2 PF07992.14 KFY01790.1 - 0.032 13.5 0.1 0.051 12.8 0.1 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 KFY01790.1 - 0.037 13.3 0.0 0.064 12.5 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain DAO PF01266.24 KFY01790.1 - 0.041 13.5 0.3 0.089 12.4 0.3 1.6 1 0 0 1 1 1 0 FAD dependent oxidoreductase Pyr_redox PF00070.27 KFY01790.1 - 0.14 12.7 0.9 0.54 10.9 0.2 2.4 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KFY01792.1 - 9.7e-11 41.7 0.3 2.2e-10 40.6 0.1 1.8 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.7 KFY01792.1 - 3.8e-08 33.1 1.3 7.1e-08 32.2 1.3 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KFY01792.1 - 1.6e-07 30.8 1.6 2.9e-07 29.9 1.6 1.4 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 KFY01792.1 - 1.6e-06 28.0 1.3 3.3e-06 26.9 1.3 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 KFY01792.1 - 3.9e-06 27.3 0.1 8.3e-06 26.3 0.1 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KFY01792.1 - 5e-06 26.0 0.1 1.4e-05 24.5 0.1 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KFY01792.1 - 1.6e-05 23.8 0.5 2.9e-05 23.0 0.5 1.4 1 0 0 1 1 1 1 HI0933-like protein Amino_oxidase PF01593.24 KFY01792.1 - 9e-05 21.9 0.0 0.00043 19.7 0.0 1.9 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase FAD_binding_3 PF01494.19 KFY01792.1 - 0.00017 21.0 0.6 0.0003 20.1 0.6 1.4 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.6 KFY01792.1 - 0.00039 19.8 0.1 0.00063 19.1 0.1 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KFY01792.1 - 0.0038 16.4 0.2 1.8 7.6 0.1 2.2 2 0 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) Thi4 PF01946.17 KFY01792.1 - 0.004 16.4 0.1 0.0069 15.6 0.1 1.3 1 0 0 1 1 1 1 Thi4 family GIDA PF01134.22 KFY01792.1 - 0.004 16.3 0.1 0.0058 15.8 0.1 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A IlvN PF07991.12 KFY01792.1 - 0.082 12.5 0.0 0.16 11.5 0.0 1.5 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain ApbA PF02558.16 KFY01792.1 - 1.6 8.4 4.3 3.4 7.3 1.0 2.6 3 0 0 3 3 3 0 Ketopantoate reductase PanE/ApbA AAA_12 PF13087.6 KFY01793.1 - 1e-36 126.4 0.0 3.4e-36 124.8 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_11 PF13086.6 KFY01793.1 - 2.2e-25 90.0 1.0 3.1e-14 53.4 0.0 2.7 3 0 0 3 3 3 2 AAA domain AAA_30 PF13604.6 KFY01793.1 - 1.4e-10 41.2 0.0 5.6e-08 32.7 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.6 KFY01793.1 - 3.6e-09 37.1 0.0 8.7e-06 26.1 0.0 2.6 2 0 0 2 2 2 2 AAA domain Viral_helicase1 PF01443.18 KFY01793.1 - 7.4e-07 29.1 0.0 0.026 14.3 0.0 3.3 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase ResIII PF04851.15 KFY01793.1 - 0.0069 16.4 0.0 0.015 15.3 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DUF2075 PF09848.9 KFY01793.1 - 0.018 14.3 0.7 0.77 8.9 0.0 2.3 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) PhoH PF02562.16 KFY01793.1 - 0.031 13.7 0.1 0.062 12.7 0.1 1.4 1 0 0 1 1 1 0 PhoH-like protein DEAD PF00270.29 KFY01793.1 - 0.13 12.1 0.0 0.25 11.1 0.0 1.5 1 0 0 1 1 1 0 DEAD/DEAH box helicase 2OG-FeII_Oxy PF03171.20 KFY01794.1 - 1.9e-14 54.0 0.0 5.8e-14 52.4 0.0 1.9 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily WD40 PF00400.32 KFY01794.1 - 1.1e-10 41.9 1.3 2.2 9.3 0.0 6.9 6 0 0 6 6 6 3 WD domain, G-beta repeat DIOX_N PF14226.6 KFY01794.1 - 7.8e-07 29.9 0.0 1.8e-06 28.7 0.0 1.5 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal PD40 PF07676.12 KFY01794.1 - 0.11 12.5 0.0 8 6.5 0.0 3.0 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat ANAPC4_WD40 PF12894.7 KFY01794.1 - 0.13 12.6 0.0 43 4.5 0.0 3.6 3 1 1 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain Nop14 PF04147.12 KFY01794.1 - 2.9 6.0 15.6 5.6 5.0 15.6 1.3 1 0 0 1 1 1 0 Nop14-like family Fungal_trans_2 PF11951.8 KFY01795.1 - 1.1e-10 40.9 0.1 1.9e-07 30.2 0.0 2.2 2 0 0 2 2 2 2 Fungal specific transcription factor domain Tet_JBP PF12851.7 KFY01795.1 - 0.0071 15.7 0.3 3.2 7.0 0.8 2.7 2 1 1 3 3 3 2 Oxygenase domain of the 2OGFeDO superfamily ADH_zinc_N PF00107.26 KFY01796.1 - 1.6e-12 47.5 0.0 3.2e-12 46.6 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KFY01796.1 - 8e-12 46.4 0.0 1.4e-11 45.6 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KFY01796.1 - 0.00016 21.5 1.1 0.01 15.7 0.9 2.4 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_N_2 PF16884.5 KFY01796.1 - 0.1 12.5 0.0 0.22 11.4 0.0 1.5 1 0 0 1 1 1 0 N-terminal domain of oxidoreductase 2-Hacid_dh_C PF02826.19 KFY01796.1 - 0.19 11.1 0.3 1 8.7 0.0 2.0 1 1 1 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Abhydrolase_1 PF00561.20 KFY01797.1 - 2.5e-26 92.9 0.0 6.4e-25 88.3 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KFY01797.1 - 4.8e-15 56.8 0.0 5.8e-15 56.5 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KFY01797.1 - 7.9e-05 22.0 0.0 0.0019 17.5 0.0 2.1 2 0 0 2 2 2 1 Serine aminopeptidase, S33 DUF1057 PF06342.12 KFY01797.1 - 0.0003 19.9 0.0 0.00055 19.1 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1057) EHN PF06441.12 KFY01797.1 - 0.047 14.1 0.3 2.7 8.4 0.0 3.0 3 0 0 3 3 3 0 Epoxide hydrolase N terminus Chlorophyllase2 PF12740.7 KFY01797.1 - 0.14 11.0 0.0 0.21 10.5 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase enzyme DUF3632 PF12311.8 KFY01799.1 - 1.6e-30 106.8 0.8 6.9e-18 65.7 0.1 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF3632) BRCA-2_helical PF09169.10 KFY01799.1 - 0.048 13.3 0.3 1.1 8.9 0.0 2.2 2 0 0 2 2 2 0 BRCA2, helical MSP1a PF11670.8 KFY01800.1 - 0.97 8.7 6.0 0.073 12.4 0.9 1.7 2 0 0 2 2 2 0 Major surface protein 1a (MSP1a) E1-E2_ATPase PF00122.20 KFY01801.1 - 9.3e-38 129.6 1.8 1.9e-37 128.6 1.1 2.0 1 1 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 KFY01801.1 - 3.9e-27 95.1 0.4 3.9e-27 95.1 0.4 3.3 4 0 0 4 4 4 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 KFY01801.1 - 4.5e-19 69.6 0.0 5.2e-08 33.4 0.0 2.7 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 KFY01801.1 - 1.4e-17 63.5 0.0 2.9e-17 62.5 0.0 1.6 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 KFY01801.1 - 1.4e-06 27.9 0.0 3.7e-06 26.5 0.0 1.8 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus WD40 PF00400.32 KFY01802.1 - 9.9e-54 178.1 17.9 6.5e-06 26.8 0.1 11.4 11 1 0 11 11 11 9 WD domain, G-beta repeat Utp13 PF08625.11 KFY01802.1 - 1.5e-52 177.3 0.2 2.5e-52 176.6 0.2 1.4 1 0 0 1 1 1 1 Utp13 specific WD40 associated domain ANAPC4_WD40 PF12894.7 KFY01802.1 - 4.5e-16 58.9 3.8 0.0032 17.7 0.1 8.0 6 2 3 9 9 9 6 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KFY01802.1 - 3.6e-06 25.9 11.5 0.14 10.7 0.2 6.5 4 4 2 6 6 6 4 Nucleoporin Nup120/160 Nucleoporin_N PF08801.11 KFY01802.1 - 3.1e-05 22.9 2.2 8.4 5.0 0.0 5.9 5 2 1 6 6 6 3 Nup133 N terminal like WD40_like PF17005.5 KFY01802.1 - 0.0038 16.6 0.0 0.24 10.7 0.0 3.4 3 1 1 4 4 4 1 WD40-like domain Glyco_hydro_125 PF06824.11 KFY01804.1 - 7.1e-187 621.4 0.0 8.9e-187 621.1 0.0 1.1 1 0 0 1 1 1 1 Metal-independent alpha-mannosidase (GH125) MFS_1 PF07690.16 KFY01804.1 - 9.7e-29 100.4 48.9 2.7e-26 92.3 30.8 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 KFY01804.1 - 0.0031 16.4 7.5 0.0031 16.4 7.5 2.1 1 1 1 2 2 2 1 MFS_1 like family Glyco_hydro_47 PF01532.20 KFY01805.1 - 3.1e-141 471.4 0.0 3.7e-141 471.2 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 FMO-like PF00743.19 KFY01806.1 - 8.4e-42 143.3 0.0 8.2e-27 93.8 0.0 3.0 3 0 0 3 3 3 3 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 KFY01806.1 - 1.7e-14 53.8 0.0 3.4e-14 52.8 0.0 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KFY01806.1 - 2.5e-12 46.7 3.1 2.2e-08 33.7 0.9 3.4 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KFY01806.1 - 2e-11 43.7 0.9 1.3e-08 34.4 0.1 2.6 2 1 1 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.6 KFY01806.1 - 5.2e-10 39.5 3.2 5.1e-08 33.1 0.4 3.3 2 2 1 3 3 3 1 FAD-NAD(P)-binding DAO PF01266.24 KFY01806.1 - 7.4e-10 38.9 2.6 0.00016 21.4 0.0 3.6 3 1 1 4 4 4 3 FAD dependent oxidoreductase Thi4 PF01946.17 KFY01806.1 - 7.1e-09 35.2 0.1 1.4e-05 24.4 0.1 2.3 2 0 0 2 2 2 2 Thi4 family NAD_binding_8 PF13450.6 KFY01806.1 - 9.1e-09 35.4 0.2 6.4e-07 29.5 0.0 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 KFY01806.1 - 4.7e-06 27.1 0.1 0.052 14.1 0.0 2.6 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KFY01806.1 - 0.0013 17.6 4.2 0.0053 15.5 0.2 2.4 3 0 0 3 3 3 1 HI0933-like protein AlaDh_PNT_C PF01262.21 KFY01806.1 - 0.0015 17.8 0.8 0.2 10.9 0.1 2.3 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain Shikimate_DH PF01488.20 KFY01806.1 - 0.0021 18.1 0.0 0.9 9.6 0.0 2.3 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase Lycopene_cycl PF05834.12 KFY01806.1 - 0.0024 17.0 0.7 0.29 10.1 0.1 2.5 2 0 0 2 2 2 1 Lycopene cyclase protein Amino_oxidase PF01593.24 KFY01806.1 - 0.0045 16.3 0.0 0.041 13.2 0.0 2.0 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase FAD_oxidored PF12831.7 KFY01806.1 - 0.009 15.4 0.2 0.069 12.5 0.0 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KFY01806.1 - 0.014 14.5 1.1 0.49 9.4 0.1 2.3 2 0 0 2 2 2 0 FAD binding domain MCRA PF06100.11 KFY01806.1 - 0.022 13.6 0.2 0.19 10.4 0.0 2.0 2 0 0 2 2 2 0 MCRA family FAD_binding_3 PF01494.19 KFY01806.1 - 0.035 13.4 0.2 0.22 10.7 0.0 2.1 2 0 0 2 2 2 0 FAD binding domain GIDA PF01134.22 KFY01806.1 - 0.039 13.0 1.4 2.6 7.0 0.1 2.4 3 0 0 3 3 3 0 Glucose inhibited division protein A Pribosyltran PF00156.27 KFY01806.1 - 0.055 13.0 0.0 0.14 11.6 0.0 1.6 1 0 0 1 1 1 0 Phosphoribosyl transferase domain 2-Hacid_dh_C PF02826.19 KFY01806.1 - 0.086 12.2 0.0 6.7 6.0 0.0 2.4 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Pyridox_ox_2 PF12900.7 KFY01807.1 - 1.7e-36 125.3 0.0 2.3e-36 124.9 0.0 1.2 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase UCH PF00443.29 KFY01809.1 - 5.6e-21 75.2 0.0 8.3e-21 74.6 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.19 KFY01809.1 - 2.1e-11 44.0 0.4 4.1e-11 43.1 0.4 1.4 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein UCH_1 PF13423.6 KFY01809.1 - 0.007 16.0 0.0 0.021 14.4 0.0 1.9 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase WD40 PF00400.32 KFY01810.1 - 1.2e-25 89.3 3.1 4.6e-07 30.4 0.0 5.8 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFY01810.1 - 0.00026 21.2 0.0 0.52 10.7 0.0 3.9 3 1 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 KFY01810.1 - 0.076 12.3 0.0 1.2 8.4 0.0 2.4 2 0 0 2 2 2 0 WD40-like domain Proteasome PF00227.26 KFY01811.1 - 2.9e-30 105.2 0.0 3.3e-30 105.0 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit Viral_DNA_bp PF00747.17 KFY01811.1 - 0.19 8.8 0.0 0.24 8.5 0.0 1.0 1 0 0 1 1 1 0 ssDNA binding protein DEAD PF00270.29 KFY01812.1 - 5.4e-47 159.8 0.0 1.8e-46 158.1 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KFY01812.1 - 3.3e-32 111.1 0.0 8.9e-32 109.7 0.0 1.7 2 0 0 2 2 2 1 Helicase conserved C-terminal domain CMS1 PF14617.6 KFY01812.1 - 0.12 11.7 0.0 0.21 10.9 0.0 1.3 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit ResIII PF04851.15 KFY01812.1 - 0.12 12.4 0.0 0.23 11.4 0.0 1.5 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 KFY01812.1 - 0.29 10.3 0.0 0.44 9.7 0.0 1.2 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase Pec_lyase_C PF00544.19 KFY01813.1 - 2.6e-15 56.6 12.0 3.4e-14 53.0 10.0 2.7 2 1 0 2 2 2 1 Pectate lyase Latrotoxin_C PF15658.6 KFY01813.1 - 6.5 6.5 6.3 7.5 6.3 0.1 3.2 4 0 0 4 4 4 0 Latrotoxin C-terminal domain DUF3445 PF11927.8 KFY01814.1 - 2.2e-64 217.2 0.0 3.1e-64 216.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3445) Acetyltransf_3 PF13302.7 KFY01814.1 - 5.9e-17 62.6 0.0 1.6e-16 61.2 0.0 1.8 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KFY01814.1 - 0.025 14.6 0.0 13 5.8 0.0 3.0 3 0 0 3 3 3 0 FR47-like protein Acetyltransf_8 PF13523.6 KFY01814.1 - 0.064 12.9 0.7 11 5.7 0.0 2.6 3 0 0 3 3 3 0 Acetyltransferase (GNAT) domain DNA_pol_E_B PF04042.16 KFY01816.1 - 7.5e-47 159.4 0.0 9.7e-47 159.0 0.0 1.1 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B DNA_pol_D_N PF18018.1 KFY01816.1 - 9.2e-41 139.0 0.0 1.4e-40 138.4 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase delta subunit OB-fold domain DUF899 PF05988.12 KFY01817.1 - 1.9e-47 161.6 0.0 2.4e-47 161.2 0.0 1.0 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF899) AA_permease PF00324.21 KFY01818.1 - 1.4e-56 192.1 35.4 1.8e-56 191.8 35.4 1.1 1 0 0 1 1 1 1 Amino acid permease SLC12 PF03522.15 KFY01818.1 - 7.2e-18 64.8 12.8 3e-08 33.1 0.0 4.4 4 1 0 4 4 4 3 Solute carrier family 12 Aa_trans PF01490.18 KFY01819.1 - 7.6e-83 278.5 33.0 9.1e-83 278.2 33.0 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein DUF202 PF02656.15 KFY01819.1 - 0.47 10.9 5.7 0.72 10.3 0.6 3.3 1 1 1 2 2 2 0 Domain of unknown function (DUF202) Arf PF00025.21 KFY01838.1 - 2e-74 248.8 0.1 2.3e-74 248.6 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 KFY01838.1 - 5.1e-15 55.7 0.0 6.7e-15 55.4 0.0 1.1 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 KFY01838.1 - 6.2e-13 48.7 0.0 6.8e-13 48.5 0.0 1.1 1 0 0 1 1 1 1 Ras family G-alpha PF00503.20 KFY01838.1 - 1.2e-12 47.7 1.4 1.4e-08 34.3 0.2 2.3 1 1 1 2 2 2 2 G-protein alpha subunit SRPRB PF09439.10 KFY01838.1 - 1.5e-11 44.0 0.0 1.9e-11 43.7 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 KFY01838.1 - 1.6e-09 37.5 0.0 2e-09 37.2 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 KFY01838.1 - 0.0002 21.4 0.0 0.00029 20.9 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.18 KFY01838.1 - 0.032 13.5 0.1 0.052 12.9 0.1 1.3 1 0 0 1 1 1 0 6-phosphofructo-2-kinase MobB PF03205.14 KFY01838.1 - 0.15 11.9 0.0 0.22 11.4 0.0 1.2 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Ank_2 PF12796.7 KFY01839.1 - 1.4e-82 272.3 2.8 7.5e-13 48.9 0.0 7.7 2 1 6 8 8 8 7 Ankyrin repeats (3 copies) Ank PF00023.30 KFY01839.1 - 9.7e-67 218.7 3.5 0.00013 22.2 0.0 13.8 14 0 0 14 14 14 12 Ankyrin repeat Ank_3 PF13606.6 KFY01839.1 - 5e-60 192.4 0.2 0.0039 17.6 0.0 14.4 14 0 0 14 14 14 12 Ankyrin repeat Ank_4 PF13637.6 KFY01839.1 - 6.9e-53 176.4 0.1 3.6e-07 30.6 0.0 9.3 4 2 7 11 11 11 11 Ankyrin repeats (many copies) Ank_5 PF13857.6 KFY01839.1 - 1.7e-46 155.6 10.4 2.7e-06 27.6 0.1 11.4 3 1 9 12 12 12 10 Ankyrin repeats (many copies) NACHT PF05729.12 KFY01839.1 - 4.3e-08 33.2 0.1 9.9e-08 32.1 0.1 1.6 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 KFY01839.1 - 8.9e-05 22.9 0.7 0.0014 19.1 0.1 2.8 2 0 0 2 2 2 1 AAA ATPase domain MltA PF03562.17 KFY01839.1 - 0.11 12.3 0.1 2.8 7.6 0.0 3.0 2 1 1 3 3 3 0 MltA specific insert domain VWA_3_C PF18571.1 KFY01839.1 - 0.13 12.1 17.9 40 4.2 0.0 8.7 10 0 0 10 10 10 0 von Willebrand factor type A C-terminal domain Torsin PF06309.11 KFY01839.1 - 0.18 11.9 0.0 0.41 10.8 0.0 1.5 1 0 0 1 1 1 0 Torsin MCM PF00493.23 KFY01840.1 - 1.1e-94 315.8 0.0 1.9e-94 315.0 0.0 1.4 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 KFY01840.1 - 3.4e-39 133.6 0.0 6e-39 132.8 0.0 1.4 1 0 0 1 1 1 1 MCM OB domain MCM2_N PF12619.8 KFY01840.1 - 2.1e-31 109.3 42.3 2.3e-31 109.2 39.7 2.2 2 0 0 2 2 2 1 Mini-chromosome maintenance protein 2 MCM_lid PF17855.1 KFY01840.1 - 1.1e-22 80.3 3.2 1.2e-22 80.1 1.5 2.1 2 0 0 2 2 2 1 MCM AAA-lid domain MCM_N PF14551.6 KFY01840.1 - 9.7e-15 55.0 0.1 2.6e-14 53.7 0.1 1.7 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 KFY01840.1 - 2e-08 33.9 0.0 2e-06 27.4 0.0 2.5 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 KFY01840.1 - 0.00013 22.0 0.0 0.00051 20.0 0.0 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.26 KFY01840.1 - 0.0011 18.7 0.1 0.29 10.8 0.0 2.3 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_3 PF07726.11 KFY01840.1 - 0.0015 18.4 0.0 0.0055 16.6 0.0 1.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activ_2 PF14532.6 KFY01840.1 - 0.13 12.4 0.0 0.85 9.7 0.0 2.2 2 0 0 2 2 2 0 Sigma-54 interaction domain AA_permease_2 PF13520.6 KFY01842.1 - 2.9e-68 230.7 45.0 3.6e-68 230.3 45.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KFY01842.1 - 4.9e-21 74.9 39.4 6.5e-21 74.5 39.4 1.1 1 0 0 1 1 1 1 Amino acid permease Malic_M PF03949.15 KFY01843.1 - 4.5e-91 304.7 0.0 6.4e-91 304.2 0.0 1.2 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.19 KFY01843.1 - 1.3e-71 240.2 0.0 2e-71 239.5 0.0 1.3 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain Ribosomal_L5e PF17144.4 KFY01844.1 - 1.6e-79 265.6 0.1 1.6e-79 265.6 0.1 1.6 2 0 0 2 2 2 1 Ribosomal large subunit proteins 60S L5, and 50S L18 Ribosomal_L18_c PF14204.6 KFY01844.1 - 2.6e-32 111.6 10.9 2.6e-32 111.6 10.9 2.0 2 0 0 2 2 2 1 Ribosomal L18 C-terminal region HAD_2 PF13419.6 KFY01845.1 - 0.00037 20.6 0.0 0.00074 19.6 0.0 1.5 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase SNF2_N PF00176.23 KFY01847.1 - 5.2e-12 45.2 0.0 6.8e-12 44.8 0.0 1.1 1 0 0 1 1 1 1 SNF2 family N-terminal domain GATase PF00117.28 KFY01848.1 - 2.2e-08 34.1 0.0 3.5e-08 33.4 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I GATase_3 PF07685.14 KFY01848.1 - 0.019 14.5 0.0 0.034 13.8 0.0 1.4 1 0 0 1 1 1 0 CobB/CobQ-like glutamine amidotransferase domain HpcH_HpaI PF03328.14 KFY01848.1 - 0.042 13.0 0.2 0.085 12.0 0.0 1.5 2 0 0 2 2 2 0 HpcH/HpaI aldolase/citrate lyase family Sugar_tr PF00083.24 KFY01849.1 - 2.3e-109 366.3 18.9 2.8e-109 366.0 18.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KFY01849.1 - 1.3e-30 106.5 31.3 1.1e-29 103.5 22.6 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_5 PF05631.14 KFY01849.1 - 0.00051 19.1 0.2 0.0011 17.9 0.2 1.5 1 0 0 1 1 1 1 Sugar-tranasporters, 12 TM Trp_oprn_chp PF09534.10 KFY01849.1 - 0.1 12.4 1.6 0.19 11.5 0.2 2.1 2 0 0 2 2 2 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) TMEM132D_C PF15706.5 KFY01849.1 - 0.95 9.3 2.7 3.4 7.5 0.6 2.3 2 0 0 2 2 2 0 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term Methyltransf_25 PF13649.6 KFY01850.1 - 6.7e-17 62.0 0.0 1.1e-16 61.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KFY01850.1 - 1e-13 51.3 0.0 1.3e-13 51.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KFY01850.1 - 1.8e-11 44.5 0.0 2.7e-11 44.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KFY01850.1 - 7.4e-11 42.2 0.0 8.4e-11 42.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KFY01850.1 - 1.5e-07 31.0 0.0 2.1e-07 30.5 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 KFY01850.1 - 4.4e-07 30.6 0.0 6.7e-07 30.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_9 PF08003.11 KFY01850.1 - 2.3e-05 23.5 0.0 3e-05 23.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Pox_MCEL PF03291.16 KFY01850.1 - 0.001 18.3 0.0 0.0015 17.7 0.0 1.2 1 0 0 1 1 1 1 mRNA capping enzyme NodS PF05401.11 KFY01850.1 - 0.0053 16.4 0.0 0.0076 15.9 0.0 1.1 1 0 0 1 1 1 1 Nodulation protein S (NodS) PrmA PF06325.13 KFY01850.1 - 0.011 15.1 0.0 0.018 14.5 0.0 1.4 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) PCMT PF01135.19 KFY01850.1 - 0.015 15.0 0.0 0.029 14.1 0.0 1.5 1 1 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Cons_hypoth95 PF03602.15 KFY01850.1 - 0.1 12.2 0.0 0.15 11.7 0.0 1.2 1 0 0 1 1 1 0 Conserved hypothetical protein 95 Methyltransf_32 PF13679.6 KFY01850.1 - 0.11 12.5 0.0 0.16 11.9 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain Peptidase_C2 PF00648.21 KFY01851.1 - 6.7e-63 212.5 0.3 3.7e-61 206.8 0.3 2.6 1 1 0 1 1 1 1 Calpain family cysteine protease DUF3543 PF12063.8 KFY01854.1 - 4.4e-86 288.3 0.7 1.4e-85 286.7 0.0 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF3543) Pkinase PF00069.25 KFY01854.1 - 3.3e-60 203.7 0.0 7.5e-60 202.5 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFY01854.1 - 2.9e-43 148.0 0.0 5.5e-43 147.1 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase Pox_ser-thr_kin PF05445.11 KFY01854.1 - 0.17 10.8 0.0 0.28 10.1 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Hemerythrin PF01814.23 KFY01861.1 - 4.1e-10 40.4 0.5 5.9e-10 39.9 0.5 1.2 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain Romo1 PF10247.9 KFY01871.1 - 1e-27 96.3 15.7 1.4e-27 95.8 15.7 1.2 1 0 0 1 1 1 1 Reactive mitochondrial oxygen species modulator 1 Tim17 PF02466.19 KFY01871.1 - 0.0054 17.1 5.5 0.0073 16.7 5.5 1.2 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family adh_short PF00106.25 KFY01879.1 - 4.3e-38 130.7 3.0 3.9e-20 72.2 0.1 2.2 1 1 1 2 2 2 2 short chain dehydrogenase MFS_1 PF07690.16 KFY01879.1 - 4.6e-30 104.7 28.1 4.6e-30 104.7 28.1 1.9 2 0 0 2 2 2 1 Major Facilitator Superfamily adh_short_C2 PF13561.6 KFY01879.1 - 3.5e-27 95.5 1.6 3.1e-14 53.1 0.2 2.2 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KFY01879.1 - 1.4e-08 34.9 5.3 1.9e-06 27.9 2.9 3.3 1 1 1 2 2 2 1 KR domain Epimerase PF01370.21 KFY01879.1 - 4.3e-06 26.4 0.1 8.3e-06 25.4 0.1 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KFY01879.1 - 0.0013 18.2 0.1 0.0021 17.5 0.1 1.3 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 KFY01879.1 - 0.0029 16.6 0.2 0.0045 16.0 0.2 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 KFY01879.1 - 0.018 14.1 0.0 0.029 13.5 0.0 1.2 1 0 0 1 1 1 0 RmlD substrate binding domain DUF2530 PF10745.9 KFY01879.1 - 0.044 14.0 1.5 0.24 11.6 0.4 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2530) DEDD_Tnp_IS110 PF01548.17 KFY01879.1 - 0.049 13.5 0.0 0.1 12.5 0.0 1.4 1 0 0 1 1 1 0 Transposase NmrA PF05368.13 KFY01879.1 - 0.052 13.1 0.3 0.1 12.1 0.3 1.5 1 0 0 1 1 1 0 NmrA-like family 2-Hacid_dh_C PF02826.19 KFY01879.1 - 0.068 12.5 0.0 0.13 11.6 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain TrkA_N PF02254.18 KFY01879.1 - 0.082 13.2 0.1 0.23 11.7 0.1 1.7 1 0 0 1 1 1 0 TrkA-N domain NAD_binding_10 PF13460.6 KFY01879.1 - 0.091 12.6 0.3 0.22 11.4 0.2 1.7 1 1 0 1 1 1 0 NAD(P)H-binding Cullin PF00888.22 KFY01880.1 - 7.9e-198 659.0 2.6 7.9e-198 659.0 2.6 1.4 2 0 0 2 2 2 1 Cullin family Cullin_Nedd8 PF10557.9 KFY01880.1 - 3.4e-27 94.3 1.9 8.9e-27 92.9 1.9 1.8 1 0 0 1 1 1 1 Cullin protein neddylation domain YpjP PF14005.6 KFY01880.1 - 0.033 14.2 1.5 0.83 9.7 0.0 3.1 4 0 0 4 4 4 0 YpjP-like protein zf-DNL PF05180.12 KFY01881.1 - 2.6e-29 100.9 0.7 3.7e-29 100.5 0.7 1.2 1 0 0 1 1 1 1 DNL zinc finger zinc_ribbon_4 PF13717.6 KFY01881.1 - 0.064 13.2 1.6 2.5 8.1 0.0 2.5 2 0 0 2 2 2 0 zinc-ribbon domain DRIM PF07539.12 KFY01882.1 - 1.3e-196 654.7 13.8 1.3e-196 654.7 9.5 2.8 2 1 0 2 2 2 1 Down-regulated in metastasis Rcd1 PF04078.13 KFY01882.1 - 0.00057 19.3 0.5 0.04 13.2 0.0 3.5 3 0 0 3 3 3 1 Cell differentiation family, Rcd1-like IBN_N PF03810.19 KFY01882.1 - 0.019 14.9 0.6 45 4.1 0.0 4.8 5 0 0 5 5 5 0 Importin-beta N-terminal domain Arm PF00514.23 KFY01882.1 - 0.024 14.7 1.1 18 5.6 0.0 4.5 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat TFCD_C PF12612.8 KFY01882.1 - 0.025 14.4 0.2 2 8.2 0.0 3.4 2 1 0 2 2 2 0 Tubulin folding cofactor D C terminal Vac14_Fab1_bd PF12755.7 KFY01882.1 - 0.13 12.9 0.1 9.8 6.9 0.0 4.1 5 0 0 5 5 5 0 Vacuolar 14 Fab1-binding region HEAT PF02985.22 KFY01882.1 - 0.67 10.4 2.0 18 5.9 0.0 4.9 5 0 0 5 5 5 0 HEAT repeat CwfJ_C_1 PF04677.15 KFY01883.1 - 4.7e-26 91.1 0.0 8.8e-26 90.2 0.0 1.4 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 CwfJ_C_2 PF04676.14 KFY01883.1 - 3.6e-17 63.1 0.3 8.1e-17 61.9 0.3 1.6 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 2 Ppx-GppA PF02541.16 KFY01884.1 - 6.1e-41 140.7 0.0 8.1e-41 140.3 0.0 1.2 1 0 0 1 1 1 1 Ppx/GppA phosphatase family GDA1_CD39 PF01150.17 KFY01884.1 - 0.16 10.6 0.1 0.27 9.9 0.1 1.3 1 0 0 1 1 1 0 GDA1/CD39 (nucleoside phosphatase) family Sld5 PF05916.11 KFY01886.1 - 1.4e-06 28.7 0.1 2.7e-06 27.8 0.1 1.5 1 0 0 1 1 1 1 GINS complex protein SLD5_C PF16922.5 KFY01886.1 - 1.7e-05 24.9 0.0 3.5e-05 23.9 0.0 1.6 1 0 0 1 1 1 1 DNA replication complex GINS protein SLD5 C-terminus Josephin PF02099.17 KFY01886.1 - 0.085 13.0 0.0 0.15 12.2 0.0 1.3 1 0 0 1 1 1 0 Josephin WD40 PF00400.32 KFY01887.1 - 7.2e-53 175.4 21.6 3.5e-10 40.3 0.5 7.4 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFY01887.1 - 4.4e-20 71.8 0.1 0.0012 19.1 0.0 6.2 2 1 4 6 6 6 6 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KFY01887.1 - 7.7e-09 35.7 0.1 0.098 12.5 0.0 4.2 2 1 2 4 4 4 3 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 KFY01887.1 - 7e-07 28.5 0.4 0.059 12.3 0.0 4.7 2 1 4 6 6 6 2 WD40 region of Ge1, enhancer of mRNA-decapping protein DUF1513 PF07433.11 KFY01887.1 - 9.9e-07 28.1 1.2 0.33 10.0 0.1 4.2 2 1 2 4 4 4 3 Protein of unknown function (DUF1513) Nup160 PF11715.8 KFY01887.1 - 5e-06 25.4 1.3 0.19 10.3 0.1 4.3 2 2 2 4 4 4 2 Nucleoporin Nup120/160 WD40_like PF17005.5 KFY01887.1 - 4.4e-05 23.0 0.0 0.00016 21.1 0.0 2.0 2 1 0 2 2 2 1 WD40-like domain PD40 PF07676.12 KFY01887.1 - 0.0009 19.1 1.0 0.64 10.0 0.0 4.4 4 0 0 4 4 4 1 WD40-like Beta Propeller Repeat Frtz PF11768.8 KFY01887.1 - 0.022 13.1 0.0 0.13 10.5 0.0 2.1 2 1 0 3 3 3 0 WD repeat-containing and planar cell polarity effector protein Fritz PALB2_WD40 PF16756.5 KFY01887.1 - 0.13 11.2 4.6 3.9 6.3 0.3 3.3 2 1 2 4 4 4 0 Partner and localizer of BRCA2 WD40 domain Mago-bind PF09282.10 KFY01888.1 - 4.2e-14 52.1 3.0 8.9e-14 51.1 3.0 1.6 1 0 0 1 1 1 1 Mago binding T4SS PF07996.11 KFY01888.1 - 0.01 16.3 2.4 0.013 15.9 2.4 1.1 1 0 0 1 1 1 0 Type IV secretion system proteins DUF4778 PF16008.5 KFY01888.1 - 0.053 13.6 3.1 0.06 13.4 3.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4778) Presenilin PF01080.17 KFY01888.1 - 0.51 9.1 5.9 0.54 9.0 5.9 1.1 1 0 0 1 1 1 0 Presenilin Dsh_C PF12316.8 KFY01888.1 - 0.53 10.7 9.8 0.62 10.4 9.3 1.3 1 1 0 1 1 1 0 Segment polarity protein dishevelled (Dsh) C terminal RR_TM4-6 PF06459.12 KFY01888.1 - 1.7 8.4 11.2 1.9 8.3 11.2 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Ndc1_Nup PF09531.10 KFY01888.1 - 9.6 4.8 6.0 10 4.7 6.0 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup UCR_UQCRX_QCR9 PF05365.12 KFY01889.1 - 1.9e-26 91.7 1.1 2.7e-26 91.3 1.1 1.2 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase, UQCRX/QCR9 like zf-UBR PF02207.20 KFY01890.1 - 7.4e-19 67.7 14.3 1.9e-18 66.4 14.3 1.8 1 0 0 1 1 1 1 Putative zinc finger in N-recognin (UBR box) Exo_endo_phos PF03372.23 KFY01890.1 - 4.5e-11 42.7 0.0 7.6e-11 42.0 0.0 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family ClpS PF02617.17 KFY01890.1 - 8.1e-07 28.7 0.1 1.7e-06 27.7 0.1 1.5 1 0 0 1 1 1 1 ATP-dependent Clp protease adaptor protein ClpS PRIMA1 PF16101.5 KFY01890.1 - 0.07 13.2 4.0 0.15 12.1 4.0 1.5 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 CAP_N PF01213.19 KFY01890.1 - 0.09 12.2 5.0 0.18 11.2 5.0 1.4 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal zf-RING_UBOX PF13445.6 KFY01890.1 - 2.4 8.2 5.6 7.7 6.6 0.1 3.6 3 0 0 3 3 3 0 RING-type zinc-finger IU_nuc_hydro PF01156.19 KFY01891.1 - 6.3e-75 252.6 0.1 1.4e-74 251.4 0.1 1.6 2 0 0 2 2 2 1 Inosine-uridine preferring nucleoside hydrolase RED_N PF07808.13 KFY01891.1 - 9.4e-07 28.6 7.9 2.4e-06 27.3 7.9 1.6 1 0 0 1 1 1 1 RED-like protein N-terminal region ApoO PF09769.9 KFY01892.1 - 1.6e-40 138.1 0.7 3.3e-38 130.6 0.1 2.8 3 0 0 3 3 3 2 Apolipoprotein O Peptidase_M3 PF01432.20 KFY01893.1 - 1.4e-123 413.6 0.0 2.4e-123 412.8 0.0 1.4 2 0 0 2 2 2 1 Peptidase family M3 Peptidase_M50B PF13398.6 KFY01893.1 - 0.061 13.0 0.1 0.091 12.4 0.1 1.2 1 0 0 1 1 1 0 Peptidase M50B-like ArAE_2 PF10334.9 KFY01893.1 - 0.061 13.2 0.0 0.16 11.8 0.0 1.7 1 0 0 1 1 1 0 Aromatic acid exporter family member 2 Rad51 PF08423.11 KFY01896.1 - 9.5e-130 431.4 0.0 1.2e-129 431.0 0.0 1.1 1 0 0 1 1 1 1 Rad51 AAA_25 PF13481.6 KFY01896.1 - 1.2e-09 38.1 0.0 1.8e-09 37.4 0.0 1.3 1 0 0 1 1 1 1 AAA domain RecA PF00154.21 KFY01896.1 - 6.8e-08 32.3 0.0 9.2e-08 31.9 0.0 1.1 1 0 0 1 1 1 1 recA bacterial DNA recombination protein HHH_5 PF14520.6 KFY01896.1 - 6.3e-06 26.7 0.5 2e-05 25.1 0.2 2.0 2 0 0 2 2 2 1 Helix-hairpin-helix domain ATPase PF06745.13 KFY01896.1 - 6.8e-06 25.6 0.1 2e-05 24.1 0.1 1.8 1 1 0 1 1 1 1 KaiC DnaB_C PF03796.15 KFY01896.1 - 0.016 14.6 0.1 0.094 12.0 0.0 1.9 2 0 0 2 2 2 0 DnaB-like helicase C terminal domain AAA_24 PF13479.6 KFY01896.1 - 0.029 14.1 0.0 0.055 13.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain ssDNA_TraI_N PF18272.1 KFY01896.1 - 0.13 12.3 0.4 0.67 10.0 0.1 2.1 2 0 0 2 2 2 0 single-stranded DNA binding TraI N-terminal subdomain PAXNEB PF05625.11 KFY01896.1 - 0.15 11.2 0.1 0.46 9.6 0.0 1.7 2 0 0 2 2 2 0 PAXNEB protein Nup160 PF11715.8 KFY01897.1 - 1.1e-140 469.9 0.0 1.4e-140 469.5 0.0 1.1 1 0 0 1 1 1 1 Nucleoporin Nup120/160 Ribosomal_L29 PF00831.23 KFY01898.1 - 1.1e-16 60.5 0.4 1.1e-16 60.5 0.4 2.1 2 1 0 2 2 2 1 Ribosomal L29 protein Wzy_C_2 PF11846.8 KFY01899.1 - 0.03 14.2 0.0 0.031 14.2 0.0 1.1 1 0 0 1 1 1 0 Virulence factor membrane-bound polymerase, C-terminal DNA_binding_1 PF01035.20 KFY01906.1 - 1.5e-20 73.1 0.1 1.7e-20 72.9 0.1 1.0 1 0 0 1 1 1 1 6-O-methylguanine DNA methyltransferase, DNA binding domain ACOX PF01756.19 KFY01907.1 - 1.8e-44 151.5 0.2 3.8e-44 150.4 0.2 1.5 1 0 0 1 1 1 1 Acyl-CoA oxidase Acyl-CoA_ox_N PF14749.6 KFY01907.1 - 7e-25 88.0 0.0 1.6e-24 86.8 0.0 1.7 1 0 0 1 1 1 1 Acyl-coenzyme A oxidase N-terminal Acyl-CoA_dh_M PF02770.19 KFY01907.1 - 8.2e-13 48.4 0.0 2.2e-12 47.0 0.0 1.8 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.24 KFY01907.1 - 3e-05 24.3 0.6 0.0021 18.3 0.6 2.4 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Thy1 PF02511.15 KFY01907.1 - 0.014 15.3 0.1 0.032 14.0 0.1 1.6 1 0 0 1 1 1 0 Thymidylate synthase complementing protein DUF1657 PF07870.11 KFY01907.1 - 0.61 10.0 3.1 2.9 7.8 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1657) ABC2_membrane PF01061.24 KFY01908.1 - 9.4e-29 100.3 28.9 9.4e-29 100.3 28.9 1.8 2 0 0 2 2 2 1 ABC-2 type transporter ABC_tran PF00005.27 KFY01908.1 - 1.8e-26 93.3 0.0 2.8e-26 92.7 0.0 1.3 1 0 0 1 1 1 1 ABC transporter RsgA_GTPase PF03193.16 KFY01908.1 - 2.7e-05 24.1 0.1 0.00027 20.9 0.0 2.2 2 0 0 2 2 2 1 RsgA GTPase AAA_21 PF13304.6 KFY01908.1 - 3.3e-05 23.8 0.8 0.058 13.2 0.0 2.3 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 KFY01908.1 - 0.00016 22.1 0.0 0.00027 21.4 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 KFY01908.1 - 0.00037 20.8 0.0 0.00092 19.5 0.0 1.7 1 1 0 1 1 1 1 AAA domain SMC_N PF02463.19 KFY01908.1 - 0.0015 18.0 0.4 0.11 11.9 0.0 2.4 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_25 PF13481.6 KFY01908.1 - 0.0018 17.9 0.0 0.0031 17.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_13 PF13166.6 KFY01908.1 - 0.0021 16.8 0.6 0.013 14.2 0.1 2.0 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 KFY01908.1 - 0.0071 16.9 0.0 0.016 15.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 KFY01908.1 - 0.0083 16.5 0.3 0.099 13.1 0.1 2.5 2 1 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) T2SSE PF00437.20 KFY01908.1 - 0.0097 15.0 0.0 0.016 14.3 0.0 1.2 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_29 PF13555.6 KFY01908.1 - 0.012 15.4 0.1 0.025 14.3 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_28 PF13521.6 KFY01908.1 - 0.036 14.3 0.0 0.065 13.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 KFY01908.1 - 0.037 13.7 0.0 0.065 12.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 KFY01908.1 - 0.071 13.3 0.0 0.15 12.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 KFY01908.1 - 0.073 12.8 0.0 0.18 11.5 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.6 KFY01908.1 - 0.11 13.0 0.3 0.28 11.7 0.0 1.7 2 0 0 2 2 1 0 AAA domain ABC2_membrane_3 PF12698.7 KFY01908.1 - 0.11 11.5 25.5 0.39 9.8 25.6 1.9 1 1 0 1 1 1 0 ABC-2 family transporter protein cobW PF02492.19 KFY01908.1 - 0.11 12.0 0.0 0.2 11.2 0.0 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain ketoacyl-synt PF00109.26 KFY01909.1 - 3.2e-80 269.4 0.0 5.3e-80 268.6 0.0 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain SAT PF16073.5 KFY01909.1 - 5.2e-72 242.5 0.2 1.8e-70 237.4 0.0 2.7 2 1 1 3 3 3 1 Starter unit:ACP transacylase in aflatoxin biosynthesis Acyl_transf_1 PF00698.21 KFY01909.1 - 5.1e-38 131.4 0.0 2.4e-37 129.2 0.0 2.0 2 0 0 2 2 2 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 KFY01909.1 - 3.7e-35 120.5 0.0 9.4e-35 119.2 0.0 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Thioesterase PF00975.20 KFY01909.1 - 3.4e-27 96.1 0.0 7.4e-27 94.9 0.0 1.6 1 0 0 1 1 1 1 Thioesterase domain PP-binding PF00550.25 KFY01909.1 - 1.1e-25 89.7 6.0 4.3e-12 46.2 0.1 3.0 3 0 0 3 3 3 2 Phosphopantetheine attachment site PS-DH PF14765.6 KFY01909.1 - 3.5e-14 52.8 0.0 5.5e-14 52.1 0.0 1.2 1 0 0 1 1 1 1 Polyketide synthase dehydratase Abhydrolase_6 PF12697.7 KFY01909.1 - 4.5e-06 27.4 0.1 0.00021 22.0 0.0 2.8 2 0 0 2 2 2 1 Alpha/beta hydrolase family KAsynt_C_assoc PF16197.5 KFY01909.1 - 9.5e-06 26.0 0.0 2.7e-05 24.6 0.0 1.8 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension Thiolase_N PF00108.23 KFY01909.1 - 0.0012 18.2 0.0 0.0025 17.2 0.0 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain AflR PF08493.10 KFY01909.1 - 0.04 13.4 6.2 0.08 12.4 6.2 1.4 1 0 0 1 1 1 0 Aflatoxin regulatory protein DUF2974 PF11187.8 KFY01909.1 - 0.087 12.4 0.0 0.2 11.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) MFS_1 PF07690.16 KFY01910.1 - 4.8e-36 124.4 32.0 4.8e-36 124.4 32.0 1.6 1 1 1 2 2 2 1 Major Facilitator Superfamily HTH_46 PF15977.5 KFY01911.1 - 0.02 14.9 0.0 0.33 11.0 0.0 2.4 2 0 0 2 2 2 0 Winged helix-turn-helix DNA binding Bromodomain PF00439.25 KFY01912.1 - 1.5e-07 31.3 0.1 2.4e-06 27.5 0.0 2.6 2 1 0 2 2 2 1 Bromodomain Striatin PF08232.12 KFY01913.1 - 0.0025 18.4 2.9 0.0037 17.9 2.9 1.3 1 0 0 1 1 1 1 Striatin family Spc7 PF08317.11 KFY01913.1 - 0.019 13.9 0.2 0.024 13.5 0.2 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein ATG16 PF08614.11 KFY01913.1 - 0.028 14.7 0.5 0.028 14.7 0.5 2.1 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) SlyX PF04102.12 KFY01913.1 - 0.038 14.6 0.1 0.092 13.4 0.1 1.7 1 0 0 1 1 1 0 SlyX DUF4855 PF16147.5 KFY01913.1 - 0.043 12.9 0.2 0.14 11.2 0.0 1.8 1 1 2 3 3 3 0 Domain of unknown function (DUF4855) tRNA-synt_1 PF00133.22 KFY01915.1 - 4.4e-38 130.9 0.0 2.4e-27 95.5 0.0 3.2 2 1 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.11 KFY01915.1 - 6.2e-16 58.1 0.0 1.1e-10 40.9 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class I (M) Anticodon_1 PF08264.13 KFY01915.1 - 8.8e-12 45.2 0.3 1.7e-11 44.3 0.3 1.6 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.19 KFY01915.1 - 9.6e-08 31.7 0.0 1.8e-07 30.8 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1_2 PF13603.6 KFY01915.1 - 0.096 12.2 0.7 9.8 5.6 0.0 2.9 3 0 0 3 3 3 0 Leucyl-tRNA synthetase, Domain 2 PurL_C PF16904.5 KFY01916.1 - 0.18 12.1 0.5 0.41 11.0 0.3 1.6 1 1 1 2 2 2 0 Phosphoribosylformylglycinamidine synthase II C-terminus Clat_adaptor_s PF01217.20 KFY01917.1 - 2.1e-41 141.2 0.1 7.7e-41 139.3 0.1 1.7 1 1 0 1 1 1 1 Clathrin adaptor complex small chain Frataxin_Cyay PF01491.16 KFY01918.1 - 7.2e-39 132.2 0.0 8.8e-39 131.9 0.0 1.1 1 0 0 1 1 1 1 Frataxin-like domain zf-CSL PF05207.13 KFY01919.1 - 4.1e-21 74.5 0.2 4.8e-21 74.2 0.2 1.1 1 0 0 1 1 1 1 CSL zinc finger Terminase_GpA PF05876.12 KFY01919.1 - 0.24 9.9 0.0 0.27 9.7 0.0 1.1 1 0 0 1 1 1 0 Phage terminase large subunit (GpA) ABC_membrane_2 PF06472.15 KFY01920.1 - 2.7e-103 345.1 1.6 4.6e-103 344.3 1.6 1.4 1 0 0 1 1 1 1 ABC transporter transmembrane region 2 ABC_tran PF00005.27 KFY01920.1 - 1.5e-17 64.4 0.0 3.7e-17 63.1 0.0 1.7 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 KFY01920.1 - 0.00023 21.1 0.0 0.00058 19.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 KFY01920.1 - 0.0072 16.8 0.2 0.11 13.0 0.0 2.2 2 0 0 2 2 2 1 AAA domain SMC_N PF02463.19 KFY01920.1 - 0.057 12.9 0.2 0.26 10.7 0.0 2.0 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 KFY01920.1 - 0.075 12.8 0.0 0.17 11.7 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain RuvB_N PF05496.12 KFY01920.1 - 0.088 12.6 0.0 0.43 10.3 0.0 2.1 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 KFY01920.1 - 0.1 13.0 0.2 0.69 10.3 0.1 2.3 2 0 0 2 2 2 0 AAA ATPase domain Rad17 PF03215.15 KFY01920.1 - 0.13 12.1 0.0 0.33 10.9 0.0 1.6 1 0 0 1 1 1 0 Rad17 P-loop domain Mg_chelatase PF01078.21 KFY01920.1 - 0.21 11.0 0.1 0.6 9.5 0.0 1.7 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI MFS_1 PF07690.16 KFY01921.1 - 6.8e-32 110.7 38.1 8.5e-32 110.4 38.1 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Methyltransf_23 PF13489.6 KFY01922.1 - 5.2e-07 29.6 0.0 0.00065 19.6 0.0 2.3 1 1 1 2 2 2 2 Methyltransferase domain Methyltransf_25 PF13649.6 KFY01922.1 - 0.00015 22.4 0.3 0.003 18.2 0.2 2.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KFY01922.1 - 0.0043 16.9 0.1 0.17 11.7 0.1 2.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_16 PF10294.9 KFY01922.1 - 0.0067 16.2 0.0 0.011 15.4 0.0 1.3 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_2 PF00891.18 KFY01922.1 - 0.0095 15.2 0.0 0.08 12.2 0.0 2.2 2 0 0 2 2 2 1 O-methyltransferase domain PrmA PF06325.13 KFY01922.1 - 0.021 14.2 0.0 0.034 13.5 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_11 PF08241.12 KFY01922.1 - 0.028 15.1 0.1 5.7 7.6 0.0 2.7 1 1 1 2 2 2 0 Methyltransferase domain Methyltransf_4 PF02390.17 KFY01922.1 - 0.1 12.0 0.0 0.3 10.6 0.0 1.7 2 0 0 2 2 2 0 Putative methyltransferase MTS PF05175.14 KFY01922.1 - 0.12 11.9 0.0 0.25 10.9 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain Beta_elim_lyase PF01212.21 KFY01923.1 - 1.3e-53 182.2 0.0 1.5e-53 182.0 0.0 1.0 1 0 0 1 1 1 1 Beta-eliminating lyase Sugar_tr PF00083.24 KFY01924.1 - 1.7e-119 399.7 42.9 4.9e-113 378.4 17.1 3.0 3 0 0 3 3 3 2 Sugar (and other) transporter MFS_1 PF07690.16 KFY01924.1 - 2.7e-68 230.5 102.7 5.5e-41 140.7 37.2 3.7 2 2 2 4 4 4 3 Major Facilitator Superfamily TRI12 PF06609.13 KFY01924.1 - 8.5e-07 27.8 21.2 8.5e-05 21.2 5.4 3.2 3 0 0 3 3 3 2 Fungal trichothecene efflux pump (TRI12) SUa-2TM PF18179.1 KFY01924.1 - 0.23 10.7 0.0 0.41 9.9 0.0 1.3 1 0 0 1 1 1 0 SMODS- and Ubiquitin system-associated 2TM effector domain Aldolase_II PF00596.21 KFY01925.1 - 1.1e-46 159.2 0.3 2e-46 158.3 0.3 1.4 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain MFS_1 PF07690.16 KFY01925.1 - 4.6e-13 48.8 26.6 7.2e-13 48.2 26.6 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily V_ATPase_I PF01496.19 KFY01925.1 - 0.1 10.5 0.0 0.16 9.9 0.0 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family CD34_antigen PF06365.12 KFY01925.1 - 0.13 11.9 0.0 0.22 11.1 0.0 1.3 1 0 0 1 1 1 0 CD34/Podocalyxin family Dus PF01207.17 KFY01929.1 - 2.5e-42 145.1 0.0 3.2e-42 144.7 0.0 1.1 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) Ldh_2 PF02615.14 KFY01930.1 - 1e-89 301.0 1.7 1.2e-89 300.8 1.7 1.0 1 0 0 1 1 1 1 Malate/L-lactate dehydrogenase NAD_binding_2 PF03446.15 KFY01931.1 - 3e-33 115.2 0.0 3.9e-33 114.9 0.0 1.1 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 KFY01931.1 - 3.4e-18 66.1 0.0 5e-18 65.5 0.0 1.3 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase F420_oxidored PF03807.17 KFY01931.1 - 0.00081 19.9 0.0 0.0031 18.1 0.0 1.9 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent OCD_Mu_crystall PF02423.15 KFY01931.1 - 0.026 13.5 0.0 0.036 13.0 0.0 1.1 1 0 0 1 1 1 0 Ornithine cyclodeaminase/mu-crystallin family GFO_IDH_MocA PF01408.22 KFY01931.1 - 0.07 14.0 0.0 0.12 13.2 0.0 1.3 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold Lactamase_B_2 PF12706.7 KFY01934.1 - 0.00036 20.1 0.0 0.00053 19.6 0.0 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 KFY01934.1 - 0.00051 20.1 6.8 0.0025 17.9 6.7 2.2 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily CMD PF02627.20 KFY01935.1 - 6.7e-20 70.9 0.3 1.9e-19 69.5 0.0 1.8 2 0 0 2 2 2 1 Carboxymuconolactone decarboxylase family MFS_1 PF07690.16 KFY01936.1 - 4.3e-28 98.2 29.1 6.3e-28 97.7 29.1 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily PNTB PF02233.16 KFY01936.1 - 0.23 10.3 6.6 0.075 11.9 1.1 2.1 2 0 0 2 2 2 0 NAD(P) transhydrogenase beta subunit FAD_binding_2 PF00890.24 KFY01937.1 - 1.7e-40 139.4 0.0 1.2e-39 136.6 0.0 1.9 1 1 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.7 KFY01937.1 - 4.5e-10 39.5 0.1 8.4e-08 32.0 0.0 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase DAO PF01266.24 KFY01937.1 - 7.4e-08 32.3 0.6 7.4e-08 32.3 0.6 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.14 KFY01937.1 - 7.2e-06 25.0 5.2 0.0022 16.8 0.1 3.1 3 0 0 3 3 3 3 HI0933-like protein Pyr_redox_2 PF07992.14 KFY01937.1 - 0.00094 18.5 2.3 0.025 13.8 2.3 2.3 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 KFY01937.1 - 0.0012 18.0 5.5 0.01 14.9 0.4 3.0 3 0 0 3 3 3 1 Glucose inhibited division protein A FAD_binding_3 PF01494.19 KFY01937.1 - 0.0063 15.8 0.1 0.051 12.8 0.0 2.0 2 0 0 2 2 2 1 FAD binding domain GMC_oxred_N PF00732.19 KFY01937.1 - 0.027 13.9 0.3 0.2 11.0 0.2 2.0 2 0 0 2 2 2 0 GMC oxidoreductase Pyr_redox_3 PF13738.6 KFY01937.1 - 0.03 13.6 0.2 4.1 6.6 0.1 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KFY01937.1 - 0.067 13.4 0.4 0.2 11.9 0.4 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Aldedh PF00171.22 KFY01938.1 - 6e-154 513.0 0.1 6.8e-154 512.8 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Fungal_trans PF04082.18 KFY01939.1 - 3.3e-22 78.8 0.0 5.4e-22 78.1 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KFY01939.1 - 1.5e-07 31.4 13.2 3e-07 30.4 13.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Aldedh PF00171.22 KFY01940.1 - 1.8e-133 445.4 0.1 2.1e-133 445.2 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.14 KFY01940.1 - 0.027 13.5 0.0 0.04 13.0 0.0 1.2 1 0 0 1 1 1 0 Acyl-CoA reductase (LuxC) Cullin PF00888.22 KFY01941.1 - 1.1e-23 83.8 0.0 2e-23 82.9 0.0 1.3 1 0 0 1 1 1 1 Cullin family ANAPC2 PF08672.11 KFY01941.1 - 4.8e-19 68.6 1.6 6.8e-19 68.1 0.1 2.1 3 0 0 3 3 3 1 Anaphase promoting complex (APC) subunit 2 FeoC PF09012.10 KFY01941.1 - 0.16 12.1 0.0 0.42 10.7 0.0 1.7 1 0 0 1 1 1 0 FeoC like transcriptional regulator Sugar_tr PF00083.24 KFY01942.1 - 1.5e-116 389.9 14.1 3.2e-116 388.9 14.1 1.5 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KFY01942.1 - 4.3e-25 88.4 44.4 2.1e-23 82.8 23.1 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 KFY01942.1 - 0.00045 18.8 3.6 0.00045 18.8 3.6 2.0 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Ni_hydr_CYTB PF01292.20 KFY01942.1 - 0.055 13.1 4.2 0.096 12.3 1.4 2.4 2 0 0 2 2 2 0 Prokaryotic cytochrome b561 TPR_11 PF13414.6 KFY01942.1 - 0.15 11.8 0.0 0.26 11.0 0.0 1.3 1 0 0 1 1 1 0 TPR repeat zf-C2H2 PF00096.26 KFY01943.1 - 0.0023 18.3 6.9 0.08 13.4 0.7 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFY01943.1 - 0.14 13.1 4.5 9.2 7.4 0.3 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger BRD4_CDT PF17105.5 KFY01943.1 - 6.7 6.4 6.7 15 5.3 6.7 1.5 1 0 0 1 1 1 0 C-terminal domain of bromodomain protein 4 HisG_C PF08029.11 KFY01945.1 - 0.16 12.2 0.0 1.5 9.0 0.0 2.0 1 1 1 2 2 2 0 HisG, C-terminal domain HR1 PF02185.16 KFY01947.1 - 0.004 17.3 2.1 0.004 17.3 2.1 3.4 3 1 0 3 3 3 1 Hr1 repeat DUF5082 PF16888.5 KFY01947.1 - 0.052 13.8 12.3 0.029 14.7 3.8 3.8 1 1 2 4 4 4 0 Domain of unknown function (DUF5082) Fib_alpha PF08702.10 KFY01947.1 - 0.1 12.8 19.0 0.27 11.4 1.9 2.7 3 0 0 3 3 3 0 Fibrinogen alpha/beta chain family DUF4533 PF15047.6 KFY01947.1 - 0.26 10.8 2.8 0.35 10.4 0.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4533) IMD PF08397.11 KFY01947.1 - 0.45 9.8 15.2 0.049 13.0 1.8 2.7 3 0 0 3 3 3 0 IRSp53/MIM homology domain DUF3450 PF11932.8 KFY01947.1 - 0.46 9.8 19.1 0.16 11.3 4.4 3.7 3 1 1 4 4 4 0 Protein of unknown function (DUF3450) DUF4709 PF15821.5 KFY01947.1 - 0.51 10.7 6.2 0.34 11.2 0.5 3.1 2 1 0 3 3 3 0 Domain of unknown function (DUF4709) FlaC_arch PF05377.11 KFY01947.1 - 0.66 10.4 12.3 2.6 8.5 0.9 4.4 2 1 2 4 4 4 0 Flagella accessory protein C (FlaC) NuDC PF16273.5 KFY01947.1 - 1.6 9.3 0.0 1.6 9.3 0.0 3.0 2 1 1 3 3 3 0 Nuclear distribution C domain Phage_Mu_Gam PF07352.12 KFY01947.1 - 1.7 8.6 10.1 1.3 8.9 4.2 3.0 3 1 0 3 3 3 0 Bacteriophage Mu Gam like protein DUF489 PF04356.12 KFY01947.1 - 2.4 8.2 7.1 12 5.9 0.4 3.5 3 1 1 4 4 4 0 Protein of unknown function (DUF489) ABC_tran_CTD PF16326.5 KFY01947.1 - 4 7.8 21.7 1.7 9.0 0.1 5.0 3 2 3 6 6 5 0 ABC transporter C-terminal domain Spc7 PF08317.11 KFY01947.1 - 5.4 5.8 22.8 1.3 7.8 5.2 2.3 1 1 1 2 2 2 0 Spc7 kinetochore protein Lzipper-MIP1 PF14389.6 KFY01947.1 - 7.2 7.0 22.7 0.46 10.8 1.1 4.7 3 2 2 5 5 5 0 Leucine-zipper of ternary complex factor MIP1 RPW8 PF05659.11 KFY01947.1 - 9.7 5.9 10.3 7.2 6.3 0.3 3.8 3 1 2 5 5 5 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 PGI PF00342.19 KFY01951.1 - 4.5e-238 790.7 2.8 5.2e-238 790.5 2.8 1.0 1 0 0 1 1 1 1 Phosphoglucose isomerase Cys_Met_Meta_PP PF01053.20 KFY01952.1 - 1.7e-135 451.5 0.0 2e-135 451.3 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.21 KFY01952.1 - 3.6e-07 29.7 0.0 5.6e-07 29.1 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 KFY01952.1 - 8e-06 25.0 0.0 5.4e-05 22.3 0.0 1.9 1 1 1 2 2 2 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 KFY01952.1 - 0.0084 15.5 0.0 0.021 14.1 0.0 1.6 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family Beta_elim_lyase PF01212.21 KFY01952.1 - 0.035 13.4 0.0 0.13 11.5 0.0 1.8 1 1 0 1 1 1 0 Beta-eliminating lyase ZFYVE21_C PF16696.5 KFY01952.1 - 0.046 13.6 0.0 0.69 9.8 0.0 2.5 3 0 0 3 3 3 0 Zinc finger FYVE domain-containing protein 21 C-terminus TQ PF18202.1 KFY01952.1 - 0.15 12.6 0.1 0.28 11.7 0.1 1.5 1 0 0 1 1 1 0 T-Q ester bond containing domain POTRA_2 PF08479.11 KFY01952.1 - 0.16 11.8 0.0 0.38 10.6 0.0 1.6 1 0 0 1 1 1 0 POTRA domain, ShlB-type Abhydrolase_6 PF12697.7 KFY01953.1 - 3.4e-19 70.3 0.0 5.1e-19 69.8 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 KFY01953.1 - 0.0023 17.4 0.0 0.0035 16.9 0.0 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family PGAP1 PF07819.13 KFY01953.1 - 0.0086 15.8 0.0 0.015 15.0 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein Lipase_2 PF01674.18 KFY01953.1 - 0.059 12.9 0.1 0.1 12.1 0.1 1.3 1 0 0 1 1 1 0 Lipase (class 2) VirB8 PF04335.13 KFY01953.1 - 0.062 13.1 0.0 0.14 12.0 0.0 1.6 1 0 0 1 1 1 0 VirB8 protein Abhydrolase_1 PF00561.20 KFY01953.1 - 0.076 12.6 0.0 0.13 11.9 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold DUF3089 PF11288.8 KFY01953.1 - 0.13 11.8 0.0 0.3 10.6 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3089) dCache_1 PF02743.18 KFY01953.1 - 0.18 11.5 0.0 0.29 10.9 0.0 1.2 1 0 0 1 1 1 0 Cache domain HATPase_c PF02518.26 KFY01954.1 - 5.2e-21 75.2 0.2 9.7e-21 74.4 0.2 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 KFY01954.1 - 1.9e-20 73.1 0.0 9.3e-20 70.9 0.0 2.1 2 0 0 2 2 2 1 Response regulator receiver domain HisKA PF00512.25 KFY01954.1 - 1.1e-10 41.4 0.4 2.8e-10 40.1 0.1 1.9 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain MS_channel PF00924.18 KFY01954.1 - 0.023 14.3 0.0 0.074 12.6 0.0 1.7 2 0 0 2 2 2 0 Mechanosensitive ion channel Cutinase PF01083.22 KFY01955.1 - 3e-50 170.6 11.0 3.5e-50 170.4 11.0 1.0 1 0 0 1 1 1 1 Cutinase PE-PPE PF08237.11 KFY01955.1 - 2.8e-05 23.8 0.6 4.5e-05 23.1 0.6 1.4 1 0 0 1 1 1 1 PE-PPE domain DUF3089 PF11288.8 KFY01955.1 - 0.025 14.1 0.0 0.038 13.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3089) Abhydrolase_1 PF00561.20 KFY01955.1 - 0.078 12.6 0.1 0.086 12.5 0.1 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KFY01955.1 - 0.11 11.8 0.1 0.14 11.4 0.1 1.2 1 0 0 1 1 1 0 Serine aminopeptidase, S33 GHMP_kinases_N PF00288.26 KFY01955.1 - 0.13 12.5 5.0 1.3 9.3 3.2 2.7 2 0 0 2 2 2 0 GHMP kinases N terminal domain VirJ PF06057.11 KFY01955.1 - 0.14 12.0 0.0 0.2 11.5 0.0 1.2 1 0 0 1 1 1 0 Bacterial virulence protein (VirJ) Semialdhyde_dh PF01118.24 KFY01958.1 - 3e-05 24.4 0.0 5.2e-05 23.7 0.0 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain NAD_binding_10 PF13460.6 KFY01958.1 - 4.9e-05 23.3 0.0 6.7e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 KFY01958.1 - 0.00014 21.5 0.0 0.00024 20.8 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family Epimerase PF01370.21 KFY01958.1 - 0.00027 20.5 0.0 0.035 13.6 0.0 2.2 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 KFY01958.1 - 0.0084 15.3 0.0 0.2 10.8 0.0 2.2 2 0 0 2 2 2 1 Male sterility protein UPF0183 PF03676.14 KFY01959.1 - 1.8e-37 129.6 0.0 2.4e-37 129.2 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0183) Kinesin PF00225.23 KFY01960.1 - 6.1e-108 360.7 0.2 6.1e-108 360.7 0.2 2.2 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 KFY01960.1 - 1.7e-23 83.2 0.1 3.2e-22 79.1 0.0 3.1 2 0 0 2 2 2 1 Microtubule binding Microtub_bind PF13931.6 KFY01960.1 - 4.2e-12 46.6 0.6 4.2e-12 46.6 0.6 5.2 4 1 0 4 4 4 1 Kinesin-associated microtubule-binding Apolipoprotein PF01442.18 KFY01960.1 - 0.0065 16.4 11.2 0.0065 16.4 11.2 4.6 1 1 1 3 3 3 1 Apolipoprotein A1/A4/E domain WXG100 PF06013.12 KFY01960.1 - 1.7 8.9 20.8 5.6 7.3 0.6 5.9 4 1 2 6 6 6 0 Proteins of 100 residues with WXG Gp-FAR-1 PF05823.12 KFY01960.1 - 2.2 8.6 19.2 8.9 6.6 0.8 4.9 2 1 3 6 6 6 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) tRNA-synt_1 PF00133.22 KFY01961.1 - 5.1e-162 540.2 0.0 7.3e-162 539.7 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.11 KFY01961.1 - 3.3e-20 72.2 0.0 9.6e-11 41.1 0.0 3.8 3 1 0 3 3 3 3 tRNA synthetases class I (M) Anticodon_1 PF08264.13 KFY01961.1 - 1.3e-16 61.0 0.0 2.7e-16 59.9 0.0 1.6 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA Fungal_trans_2 PF11951.8 KFY01961.1 - 2.4e-06 26.6 2.8 0.00044 19.2 0.2 2.3 2 0 0 2 2 2 2 Fungal specific transcription factor domain tRNA-synt_1_2 PF13603.6 KFY01961.1 - 0.026 14.0 0.0 0.05 13.1 0.0 1.4 1 0 0 1 1 1 0 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1e PF01406.19 KFY01961.1 - 0.18 11.1 0.0 12 5.1 0.0 2.2 2 0 0 2 2 2 0 tRNA synthetases class I (C) catalytic domain Lysine_decarbox PF03641.14 KFY01962.1 - 3.3e-12 46.7 0.0 6.1e-07 29.6 0.0 2.2 2 0 0 2 2 2 2 Possible lysine decarboxylase LDcluster4 PF18306.1 KFY01962.1 - 0.0038 16.8 0.4 0.0068 16.0 0.1 1.6 2 0 0 2 2 2 1 SLOG cluster4 family WD40 PF00400.32 KFY01963.1 - 4.4e-116 375.5 42.2 1.6e-10 41.3 0.2 13.8 13 0 0 13 13 13 12 WD domain, G-beta repeat SesA PF17107.5 KFY01963.1 - 1.2e-33 115.9 0.1 3.3e-33 114.4 0.1 1.9 1 0 0 1 1 1 1 N-terminal domain on NACHT_NTPase and P-loop NTPases ANAPC4_WD40 PF12894.7 KFY01963.1 - 1.2e-32 112.1 8.4 0.24 11.7 0.0 12.8 1 1 10 12 12 12 11 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 KFY01963.1 - 8.4e-17 60.6 2.1 7.4 6.6 0.0 11.5 12 0 0 12 12 12 2 WD40-like Beta Propeller Repeat Ge1_WD40 PF16529.5 KFY01963.1 - 2.3e-12 46.5 13.5 0.09 11.7 0.0 10.1 2 2 8 11 11 11 5 WD40 region of Ge1, enhancer of mRNA-decapping protein NACHT PF05729.12 KFY01963.1 - 2.8e-12 46.9 0.5 5.7e-12 45.9 0.5 1.5 1 0 0 1 1 1 1 NACHT domain SH3_18 PF18354.1 KFY01963.1 - 7.3e-05 22.7 0.0 11 6.2 0.0 6.5 6 1 1 7 7 7 1 CarS bacterial SH3 domain CobA_CobO_BtuR PF02572.15 KFY01963.1 - 0.016 15.5 0.0 0.038 14.2 0.0 1.6 1 0 0 1 1 1 0 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP KAP_NTPase PF07693.14 KFY01963.1 - 0.083 12.1 0.1 0.16 11.2 0.1 1.4 1 0 0 1 1 1 0 KAP family P-loop domain Tli4_C PF18426.1 KFY01963.1 - 0.083 13.2 0.6 83 3.4 0.0 4.7 6 0 0 6 6 6 0 Tle cognate immunity protein 4 C-terminal domain HARP PF07443.13 KFY01963.1 - 0.17 11.6 0.2 50 3.6 0.0 3.5 3 0 0 3 3 3 0 HepA-related protein (HARP) Fic PF02661.18 KFY01985.1 - 5.1e-20 72.2 0.0 2.4e-19 70.0 0.0 2.1 3 0 0 3 3 3 1 Fic/DOC family PH PF00169.29 KFY01986.1 - 2.4e-05 24.8 0.1 5.8e-05 23.6 0.1 1.7 1 0 0 1 1 1 1 PH domain Prominin PF05478.11 KFY01986.1 - 0.14 10.0 0.2 0.23 9.4 0.2 1.2 1 0 0 1 1 1 0 Prominin tRNA-synt_2b PF00587.25 KFY01987.1 - 3e-32 112.0 0.0 5.6e-29 101.4 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 KFY01987.1 - 1.2e-18 67.0 0.1 3.2e-18 65.7 0.0 1.8 2 0 0 2 2 2 1 Anticodon binding domain TGS PF02824.21 KFY01987.1 - 5.7e-13 48.7 0.0 1.4e-12 47.5 0.0 1.6 1 0 0 1 1 1 1 TGS domain tRNA_SAD PF07973.14 KFY01987.1 - 2e-12 47.0 0.0 4.5e-12 45.9 0.0 1.7 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain Gar1 PF04410.14 KFY01988.1 - 3.5e-38 130.8 0.0 4.5e-38 130.4 0.0 1.0 1 0 0 1 1 1 1 Gar1/Naf1 RNA binding region DUF2013 PF09431.10 KFY01989.1 - 2.5e-50 170.2 4.4 2.5e-50 170.2 4.4 2.1 2 1 1 3 3 3 1 Protein of unknown function (DUF2013) RHH_4 PF13467.6 KFY01989.1 - 0.088 12.7 0.1 0.34 10.8 0.0 1.9 2 0 0 2 2 2 0 Ribbon-helix-helix domain DnaJ PF00226.31 KFY01990.1 - 2.3e-19 69.3 5.3 3.1e-19 68.9 1.2 3.1 3 0 0 3 3 3 1 DnaJ domain TPR_1 PF00515.28 KFY01990.1 - 9.7e-15 53.7 0.0 0.0017 18.1 0.0 5.5 5 0 0 5 5 4 4 Tetratricopeptide repeat TPR_2 PF07719.17 KFY01990.1 - 1.2e-13 50.0 0.2 0.098 12.8 0.0 6.9 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_8 PF13181.6 KFY01990.1 - 8.5e-12 44.3 0.8 0.027 14.6 0.0 7.1 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_19 PF14559.6 KFY01990.1 - 6.5e-09 36.2 1.4 0.0094 16.4 0.0 4.8 3 1 0 4 4 4 2 Tetratricopeptide repeat TPR_9 PF13371.6 KFY01990.1 - 1.8e-08 34.4 0.1 0.02 15.1 0.0 4.3 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_6 PF13174.6 KFY01990.1 - 3.9e-07 30.3 0.0 0.077 13.7 0.0 5.3 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_17 PF13431.6 KFY01990.1 - 1.1e-06 28.6 0.1 0.0036 17.6 0.0 4.9 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_7 PF13176.6 KFY01990.1 - 1.2e-06 28.1 0.0 0.0061 16.5 0.0 4.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.6 KFY01990.1 - 4.8e-05 23.8 0.0 3.6 8.6 0.0 5.8 2 2 5 8 8 8 1 Tetratricopeptide repeat TPR_11 PF13414.6 KFY01990.1 - 0.00039 20.1 0.3 0.0052 16.4 0.0 2.9 3 0 0 3 3 3 1 TPR repeat ANAPC3 PF12895.7 KFY01990.1 - 0.00039 20.6 7.4 13 6.0 0.0 4.6 4 0 0 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.6 KFY01990.1 - 0.00075 19.7 4.4 0.12 12.6 0.0 5.2 5 1 1 6 6 6 2 Tetratricopeptide repeat PknG_TPR PF16918.5 KFY01990.1 - 0.00092 18.0 0.0 0.0068 15.2 0.0 2.1 2 0 0 2 2 2 1 Protein kinase G tetratricopeptide repeat Transcrip_act PF04949.13 KFY01990.1 - 0.031 14.1 0.9 1.7 8.5 0.2 2.7 2 0 0 2 2 2 0 Transcriptional activator TPR_10 PF13374.6 KFY01990.1 - 0.045 13.6 1.1 9.4 6.3 0.0 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_16 PF13432.6 KFY01990.1 - 0.046 14.4 0.0 5 7.8 0.0 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF1732 PF08340.11 KFY01991.1 - 0.073 13.1 0.5 0.2 11.7 0.2 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF1732) Vac14_Fig4_bd PF11916.8 KFY01992.1 - 4.2e-81 270.9 8.1 4.2e-81 270.9 8.1 2.0 3 0 0 3 3 3 1 Vacuolar protein 14 C-terminal Fig4p binding Vac14_Fab1_bd PF12755.7 KFY01992.1 - 1.3e-45 153.9 0.0 2e-42 143.7 0.0 4.1 4 0 0 4 4 4 1 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.6 KFY01992.1 - 9.4e-11 42.0 2.9 0.0047 17.4 0.1 5.4 4 1 1 5 5 5 3 HEAT-like repeat HEAT PF02985.22 KFY01992.1 - 4.9e-08 32.6 1.0 0.0019 18.3 0.0 5.8 4 0 0 4 4 4 1 HEAT repeat Cnd1 PF12717.7 KFY01992.1 - 7.7e-06 26.0 0.2 0.005 16.9 0.4 3.2 3 0 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 KFY01992.1 - 0.00012 22.4 2.4 0.37 11.2 0.0 5.0 5 1 0 5 5 5 1 HEAT repeats CLASP_N PF12348.8 KFY01992.1 - 0.011 15.3 0.1 2.1 7.8 0.0 3.9 3 1 1 4 4 4 0 CLASP N terminal Arm PF00514.23 KFY01992.1 - 0.019 15.0 0.0 16 5.7 0.0 4.5 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat Fungal_trans PF04082.18 KFY01999.1 - 1.8e-28 99.3 0.7 3.5e-28 98.4 0.7 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KFY01999.1 - 2.6e-08 33.9 14.9 5.7e-08 32.8 14.9 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain bZIP_1 PF00170.21 KFY01999.1 - 0.078 13.1 0.1 0.26 11.4 0.1 1.9 1 0 0 1 1 1 0 bZIP transcription factor SET PF00856.28 KFY02000.1 - 6.2e-08 33.2 0.0 1.8e-07 31.7 0.0 1.8 2 1 0 2 2 2 1 SET domain MMR_HSR1_C PF08438.10 KFY02002.1 - 5.3e-35 120.4 0.0 8.8e-35 119.7 0.0 1.4 1 0 0 1 1 1 1 GTPase of unknown function C-terminal MMR_HSR1 PF01926.23 KFY02002.1 - 8.7e-22 77.4 0.0 3.1e-21 75.6 0.0 1.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 KFY02002.1 - 7.3e-10 38.6 0.1 1.2e-07 31.4 0.0 2.4 2 0 0 2 2 2 1 Ferrous iron transport protein B Dynamin_N PF00350.23 KFY02002.1 - 0.0018 18.4 0.8 0.12 12.4 0.1 2.6 3 0 0 3 3 3 1 Dynamin family GTP_EFTU PF00009.27 KFY02002.1 - 0.0042 16.7 0.3 0.81 9.2 0.0 2.6 3 0 0 3 3 3 1 Elongation factor Tu GTP binding domain ATP_bind_1 PF03029.17 KFY02002.1 - 0.0044 16.8 0.1 1 9.1 0.0 2.2 2 0 0 2 2 2 2 Conserved hypothetical ATP binding protein VirB8 PF04335.13 KFY02002.1 - 0.011 15.6 0.0 0.019 14.8 0.0 1.2 1 0 0 1 1 1 0 VirB8 protein RsgA_GTPase PF03193.16 KFY02002.1 - 0.036 14.0 0.5 1.4 8.8 0.1 2.3 2 0 0 2 2 2 0 RsgA GTPase MMR_HSR1_Xtn PF16897.5 KFY02002.1 - 0.042 13.9 0.1 0.092 12.8 0.1 1.5 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain AstB PF04996.12 KFY02002.1 - 0.072 11.7 0.0 0.12 11.0 0.0 1.3 1 0 0 1 1 1 0 Succinylarginine dihydrolase KTI12 PF08433.10 KFY02002.1 - 0.097 12.1 0.0 0.22 10.9 0.0 1.6 1 0 0 1 1 1 0 Chromatin associated protein KTI12 Ploopntkinase3 PF18751.1 KFY02002.1 - 0.11 12.4 0.0 0.23 11.3 0.0 1.5 1 0 0 1 1 1 0 P-loop Nucleotide Kinase3 ABC_tran PF00005.27 KFY02002.1 - 0.12 12.8 0.1 0.71 10.4 0.0 2.0 2 0 0 2 2 2 0 ABC transporter DJ-1_PfpI PF01965.24 KFY02010.1 - 1.3e-12 47.9 0.0 1.6e-12 47.6 0.0 1.1 1 0 0 1 1 1 1 DJ-1/PfpI family GATase PF00117.28 KFY02010.1 - 0.049 13.4 0.0 0.049 13.4 0.0 1.2 1 1 0 1 1 1 0 Glutamine amidotransferase class-I Pkinase PF00069.25 KFY02011.1 - 9.7e-24 84.1 0.0 4.4e-22 78.7 0.0 2.5 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFY02011.1 - 3.2e-09 36.4 0.0 4.1e-08 32.8 0.0 2.4 2 1 0 2 2 2 1 Protein tyrosine kinase FMO-like PF00743.19 KFY02012.1 - 3.5e-12 45.5 0.1 1.2e-10 40.5 0.0 2.4 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 KFY02012.1 - 1.2e-11 44.5 0.0 1.4e-09 37.7 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KFY02012.1 - 3.7e-09 36.3 0.0 4.9e-08 32.6 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KFY02012.1 - 5.3e-08 32.4 0.0 3.2e-06 26.5 0.0 2.4 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 KFY02012.1 - 0.00014 22.0 0.0 0.13 12.5 0.0 2.6 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 KFY02012.1 - 0.004 17.2 0.4 16 5.5 0.1 4.4 4 1 1 5 5 5 1 FAD-NAD(P)-binding Pyr_redox PF00070.27 KFY02012.1 - 0.013 16.0 0.1 1.1 9.9 0.0 2.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.18 KFY02012.1 - 0.085 13.1 2.4 38 4.6 0.2 4.3 5 0 0 5 5 5 0 TrkA-N domain NAD_binding_7 PF13241.6 KFY02012.1 - 0.12 12.8 0.0 6.7 7.2 0.0 2.7 2 0 0 2 2 2 0 Putative NAD(P)-binding MFS_1 PF07690.16 KFY02013.1 - 4.8e-13 48.7 34.1 7.9e-13 48.1 34.1 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily UNC-93 PF05978.16 KFY02013.1 - 1.2e-09 38.1 7.3 1.2e-09 38.1 7.3 2.8 3 1 0 3 3 3 1 Ion channel regulatory protein UNC-93 OppC_N PF12911.7 KFY02013.1 - 0.038 14.0 0.7 2 8.5 0.0 3.0 3 0 0 3 3 3 0 N-terminal TM domain of oligopeptide transport permease C SSF PF00474.17 KFY02032.1 - 6.6e-22 77.9 34.8 1e-21 77.3 34.8 1.3 1 0 0 1 1 1 1 Sodium:solute symporter family zinc_ribbon_15 PF17032.5 KFY02033.1 - 9.4e-06 26.3 0.4 1.3e-05 25.8 0.4 1.2 1 0 0 1 1 1 1 zinc-ribbon family zf-piccolo PF05715.13 KFY02033.1 - 0.18 12.0 5.1 3.8 7.7 0.0 2.4 2 0 0 2 2 2 0 Piccolo Zn-finger GrpE PF01025.19 KFY02034.1 - 0.0096 15.6 1.8 0.023 14.4 1.7 1.6 1 1 0 1 1 1 1 GrpE Zmiz1_N PF18028.1 KFY02034.1 - 0.078 13.3 0.1 0.14 12.5 0.1 1.4 1 0 0 1 1 1 0 Zmiz1 N-terminal tetratricopeptide repeat domain CinA PF02464.17 KFY02035.1 - 6.2e-34 116.8 0.2 7.4e-34 116.5 0.2 1.1 1 0 0 1 1 1 1 Competence-damaged protein DUF155 PF02582.14 KFY02036.1 - 2.7e-54 183.9 0.1 3.9e-54 183.4 0.1 1.3 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 DUF1218 PF06749.12 KFY02036.1 - 0.022 15.3 0.1 0.058 13.9 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1218) ECSCR PF15820.5 KFY02036.1 - 0.045 13.6 0.2 0.11 12.3 0.2 1.6 1 0 0 1 1 1 0 Endothelial cell-specific chemotaxis regulator PIG-X PF08320.12 KFY02037.1 - 3.1e-43 148.1 0.2 7e-43 147.0 0.0 1.7 2 0 0 2 2 2 1 PIG-X / PBN1 SesA PF17107.5 KFY02041.1 - 8.1e-06 26.0 0.3 4.2e-05 23.7 0.1 1.8 1 1 1 2 2 2 1 N-terminal domain on NACHT_NTPase and P-loop NTPases Alpha-amylase PF00128.24 KFY02051.1 - 2.7e-57 194.8 0.0 3.6e-57 194.4 0.0 1.1 1 0 0 1 1 1 1 Alpha amylase, catalytic domain DUF1966 PF09260.11 KFY02051.1 - 5.7e-14 52.2 0.2 1.5e-13 50.8 0.2 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1966) ABC2_membrane PF01061.24 KFY02051.1 - 0.14 11.6 0.1 0.36 10.2 0.1 1.7 1 0 0 1 1 1 0 ABC-2 type transporter Glyco_hydro_15 PF00723.21 KFY02052.1 - 4.6e-100 335.5 0.3 5.2e-100 335.3 0.3 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 15 CDH-cyt PF16010.5 KFY02053.1 - 6e-49 166.2 0.9 1.2e-48 165.2 0.9 1.5 1 0 0 1 1 1 1 Cytochrome domain of cellobiose dehydrogenase GMC_oxred_N PF00732.19 KFY02053.1 - 7.9e-25 87.8 0.1 8.6e-24 84.4 0.1 2.2 1 1 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KFY02053.1 - 1.1e-19 71.3 0.0 1.1e-19 71.3 0.0 1.8 2 0 0 2 2 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 KFY02053.1 - 4.4e-09 35.9 0.0 8.4e-09 35.0 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 KFY02053.1 - 0.00028 20.6 0.2 0.0083 15.7 0.1 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 KFY02053.1 - 0.00069 18.9 0.3 0.0017 17.7 0.1 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KFY02053.1 - 0.0014 17.9 0.0 0.057 12.7 0.1 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KFY02053.1 - 0.0032 17.7 0.0 0.0088 16.3 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 KFY02053.1 - 0.0037 17.8 0.1 0.34 11.5 0.3 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KFY02053.1 - 0.0063 15.3 0.1 0.0099 14.6 0.1 1.2 1 0 0 1 1 1 1 HI0933-like protein FAD_oxidored PF12831.7 KFY02053.1 - 0.047 13.0 0.2 0.14 11.5 0.3 1.7 2 0 0 2 2 2 0 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 KFY02053.1 - 0.093 12.0 0.8 0.15 11.2 0.2 1.6 2 0 0 2 2 2 0 FAD binding domain Lycopene_cycl PF05834.12 KFY02053.1 - 0.12 11.4 0.2 0.19 10.8 0.2 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein LPMO_10 PF03067.15 KFY02054.1 - 3.3e-07 31.1 4.6 6.6e-07 30.2 4.6 1.5 1 1 0 1 1 1 1 Lytic polysaccharide mono-oxygenase, cellulose-degrading adh_short PF00106.25 KFY02055.1 - 5.6e-16 58.6 0.0 3e-13 49.7 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase KR PF08659.10 KFY02055.1 - 2.9e-08 33.8 0.0 4e-08 33.4 0.0 1.2 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.6 KFY02055.1 - 2.2e-06 27.4 0.0 3.2e-06 26.9 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 KFY02055.1 - 0.0054 16.2 0.0 0.0091 15.5 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family HeLo PF14479.6 KFY02056.1 - 3.4e-16 59.7 0.1 3.8e-16 59.5 0.1 1.0 1 0 0 1 1 1 1 Prion-inhibition and propagation Cupin_2 PF07883.11 KFY02057.1 - 0.0096 15.6 4.4 0.74 9.6 0.1 3.4 3 1 0 3 3 3 2 Cupin domain PMI_typeI PF01238.21 KFY02057.1 - 0.011 15.0 0.0 0.022 13.9 0.0 1.5 1 0 0 1 1 1 0 Phosphomannose isomerase type I Mannosidase_ig PF17786.1 KFY02058.1 - 8.4e-17 61.6 0.1 2.2e-16 60.2 0.1 1.8 1 0 0 1 1 1 1 Mannosidase Ig/CBM-like domain Glyco_hydro_2 PF00703.21 KFY02058.1 - 3.2e-09 37.4 0.0 8.3e-09 36.1 0.0 1.8 1 0 0 1 1 1 1 Glycosyl hydrolases family 2 Ig_mannosidase PF17753.1 KFY02058.1 - 0.00023 20.8 2.0 0.00044 19.9 0.0 2.4 3 0 0 3 3 3 1 Ig-fold domain Glyco_hydro_2_N PF02837.18 KFY02058.1 - 0.0027 17.6 0.1 0.0053 16.7 0.1 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain Sugar_tr PF00083.24 KFY02059.1 - 1.2e-85 288.1 24.5 1.3e-85 287.9 24.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KFY02059.1 - 2.2e-22 79.5 21.0 2.2e-22 79.5 21.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 KFY02059.1 - 4.1e-06 25.5 2.4 9.2e-06 24.4 2.4 1.5 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) VIT1 PF01988.19 KFY02059.1 - 5.5 6.8 6.8 4.2 7.2 4.4 2.0 2 1 0 2 2 2 0 VIT family Fungal_trans_2 PF11951.8 KFY02060.1 - 2.2e-08 33.3 3.5 1.2e-07 30.9 3.5 1.9 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KFY02060.1 - 9.6e-08 32.0 12.2 1.8e-07 31.2 12.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KFY02060.1 - 0.027 13.5 0.3 0.085 11.9 0.3 2.0 1 1 0 1 1 1 0 Fungal specific transcription factor domain DndB PF14072.6 KFY02060.1 - 0.14 11.4 0.2 0.23 10.6 0.2 1.3 1 0 0 1 1 1 0 DNA-sulfur modification-associated Metallophos PF00149.28 KFY02061.1 - 1.7e-08 35.2 0.0 3.7e-08 34.1 0.0 1.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 KFY02061.1 - 7.6e-07 29.5 0.0 6.3e-05 23.2 0.0 2.1 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Putative_PNPOx PF01243.20 KFY02062.1 - 0.00015 21.9 0.0 0.00029 21.0 0.0 1.4 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase F-box-like PF12937.7 KFY02065.1 - 1.1e-08 34.9 2.5 0.012 15.5 0.0 4.2 5 0 0 5 5 5 2 F-box-like F-box PF00646.33 KFY02065.1 - 9.1e-05 22.2 0.1 7.6 6.5 0.0 3.8 3 0 0 3 3 3 3 F-box domain TPR_10 PF13374.6 KFY02066.1 - 4.6e-108 350.6 19.0 6.7e-10 38.5 0.0 11.6 11 0 0 11 11 11 11 Tetratricopeptide repeat TPR_12 PF13424.6 KFY02066.1 - 1.5e-81 268.7 15.1 1.6e-13 50.7 0.1 11.0 1 1 10 11 11 11 11 Tetratricopeptide repeat TPR_MalT PF17874.1 KFY02066.1 - 7.9e-16 58.4 33.7 7e-08 32.2 7.5 6.0 2 1 3 5 5 5 3 MalT-like TPR region TPR_4 PF07721.14 KFY02066.1 - 8.2e-13 47.7 0.0 6.6 7.7 0.0 9.2 10 0 0 10 10 9 2 Tetratricopeptide repeat TPR_2 PF07719.17 KFY02066.1 - 1.5e-10 40.3 1.9 3.4 8.0 0.0 8.8 10 0 0 10 10 10 2 Tetratricopeptide repeat TPR_1 PF00515.28 KFY02066.1 - 1.6e-10 40.4 0.8 8.3 6.4 0.1 8.8 10 0 0 10 10 10 1 Tetratricopeptide repeat TPR_17 PF13431.6 KFY02066.1 - 4.8e-09 36.0 4.5 0.67 10.5 0.0 9.8 11 0 0 11 11 11 1 Tetratricopeptide repeat TPR_19 PF14559.6 KFY02066.1 - 1.2e-05 25.7 5.4 0.054 14.0 0.0 5.4 4 1 3 7 7 7 1 Tetratricopeptide repeat TPR_7 PF13176.6 KFY02066.1 - 1.8e-05 24.5 13.7 1.4 9.1 0.0 8.5 9 0 0 9 9 8 1 Tetratricopeptide repeat TPR_16 PF13432.6 KFY02066.1 - 0.0012 19.5 0.1 78 4.0 0.0 5.9 5 1 0 6 6 6 0 Tetratricopeptide repeat Imm49 PF15575.6 KFY02066.1 - 0.0072 16.1 0.2 2 8.1 0.1 3.8 1 1 3 4 4 4 1 Immunity protein 49 Enolase_C PF00113.22 KFY02066.1 - 0.011 15.0 1.9 14 4.9 0.0 4.9 2 1 4 6 6 6 0 Enolase, C-terminal TIM barrel domain Guanylate_cyc_2 PF09778.9 KFY02066.1 - 0.019 14.3 3.9 6.1 6.1 0.1 4.6 2 1 3 5 5 5 0 Guanylylate cyclase TadF PF16964.5 KFY02066.1 - 0.056 13.2 3.3 32 4.2 0.1 4.4 4 0 0 4 4 4 0 Putative tight adherence pilin protein F DUF3305 PF11749.8 KFY02066.1 - 0.12 12.4 0.0 1.5 8.9 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3305) TPR_8 PF13181.6 KFY02066.1 - 0.19 12.0 7.0 52 4.4 0.0 6.2 9 0 0 9 9 7 0 Tetratricopeptide repeat AviRa PF11599.8 KFY02066.1 - 0.25 10.8 15.5 6.7 6.1 0.1 5.1 3 1 1 5 5 5 0 RRNA methyltransferase AviRa TPR_15 PF13429.6 KFY02066.1 - 0.31 10.2 4.2 0.73 9.0 0.4 3.4 2 1 1 3 3 3 0 Tetratricopeptide repeat DUF1793 PF08760.11 KFY02066.1 - 7.4 7.0 6.3 26 5.2 0.0 4.0 4 1 1 5 5 5 0 Domain of unknown function (DUF1793) Filament PF00038.21 KFY02067.1 - 0.00044 19.9 7.7 0.0064 16.1 0.7 3.0 3 0 0 3 3 3 1 Intermediate filament protein CLZ PF16526.5 KFY02067.1 - 0.0024 18.2 1.8 0.31 11.4 0.0 4.2 4 1 1 5 5 5 1 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Sec34 PF04136.15 KFY02067.1 - 0.0026 17.7 1.3 2.9 7.8 0.0 3.0 3 1 0 3 3 3 2 Sec34-like family Sporozoite_P67 PF05642.11 KFY02067.1 - 0.0058 14.8 0.0 0.012 13.8 0.0 1.4 2 0 0 2 2 2 1 Sporozoite P67 surface antigen ZapB PF06005.12 KFY02067.1 - 0.0089 16.4 5.5 6.3 7.3 0.3 3.6 3 0 0 3 3 3 0 Cell division protein ZapB DUF4515 PF14988.6 KFY02067.1 - 0.016 15.1 0.4 0.016 15.1 0.4 2.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4515) PKcGMP_CC PF16808.5 KFY02067.1 - 0.022 14.6 0.6 0.022 14.6 0.6 3.1 4 0 0 4 4 2 0 Coiled-coil N-terminus of cGMP-dependent protein kinase TSC22 PF01166.18 KFY02067.1 - 0.024 14.9 0.5 13 6.1 0.0 3.8 4 0 0 4 4 4 0 TSC-22/dip/bun family WXG100 PF06013.12 KFY02067.1 - 0.028 14.7 0.0 1e+02 3.2 0.0 4.2 4 1 0 4 4 4 0 Proteins of 100 residues with WXG DUF1664 PF07889.12 KFY02067.1 - 0.028 14.5 1.9 4 7.5 0.1 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) DUF641 PF04859.12 KFY02067.1 - 0.044 14.1 0.2 0.044 14.1 0.2 2.9 3 1 0 3 3 3 0 Plant protein of unknown function (DUF641) Tup_N PF08581.10 KFY02067.1 - 0.053 13.8 0.5 2 8.8 0.0 3.0 2 1 0 2 2 2 0 Tup N-terminal TMF_TATA_bd PF12325.8 KFY02067.1 - 0.066 13.4 13.1 0.1 12.8 0.7 4.1 3 1 0 4 4 4 0 TATA element modulatory factor 1 TATA binding DUF148 PF02520.17 KFY02067.1 - 0.077 13.1 0.1 30 4.8 0.0 3.2 3 1 0 3 3 3 0 Domain of unknown function DUF148 SHE3 PF17078.5 KFY02067.1 - 0.089 12.5 3.7 2.4 7.8 0.0 3.0 2 2 0 2 2 2 0 SWI5-dependent HO expression protein 3 ApoO PF09769.9 KFY02067.1 - 0.094 12.7 0.3 1 9.3 0.0 2.8 3 1 0 3 3 3 0 Apolipoprotein O Retrotran_gag_2 PF14223.6 KFY02067.1 - 0.12 12.0 0.2 1.5 8.5 0.0 2.6 3 0 0 3 3 3 0 gag-polypeptide of LTR copia-type Fzo_mitofusin PF04799.13 KFY02067.1 - 0.13 11.8 2.2 2.1 7.8 0.1 3.0 3 0 0 3 3 3 0 fzo-like conserved region Cortex-I_coil PF09304.10 KFY02067.1 - 0.2 11.9 3.6 12 6.1 0.0 3.1 3 0 0 3 3 3 0 Cortexillin I, coiled coil Seryl_tRNA_N PF02403.22 KFY02067.1 - 0.34 11.2 3.9 12 6.2 0.1 3.3 3 0 0 3 3 3 0 Seryl-tRNA synthetase N-terminal domain SOGA PF11365.8 KFY02067.1 - 0.35 12.0 0.1 0.35 12.0 0.1 2.8 3 1 0 3 3 2 0 Protein SOGA SNARE PF05739.19 KFY02067.1 - 0.43 10.6 1.5 14 5.7 0.0 2.6 2 0 0 2 2 2 0 SNARE domain FlaC_arch PF05377.11 KFY02067.1 - 0.63 10.5 2.6 14 6.2 0.0 3.9 5 0 0 5 5 4 0 Flagella accessory protein C (FlaC) PhoU PF01895.19 KFY02067.1 - 0.81 10.2 3.1 4.4 7.8 0.1 3.0 3 0 0 3 3 3 0 PhoU domain DUF5082 PF16888.5 KFY02067.1 - 0.84 9.9 6.8 3.8 7.8 0.4 3.7 3 2 1 4 4 4 0 Domain of unknown function (DUF5082) Golgin_A5 PF09787.9 KFY02067.1 - 1.3 8.5 9.9 0.12 11.8 1.4 2.7 2 1 1 3 3 3 0 Golgin subfamily A member 5 Csm1_N PF18504.1 KFY02067.1 - 2 8.8 5.0 10 6.5 0.6 3.9 3 2 2 5 5 5 0 Csm1 N-terminal domain APG6_N PF17675.1 KFY02067.1 - 2.3 8.8 11.5 0.23 12.0 0.5 3.3 2 1 1 3 3 3 0 Apg6 coiled-coil region Lebercilin PF15619.6 KFY02067.1 - 4.4 6.9 12.2 0.066 12.9 1.2 2.9 3 0 0 3 3 3 0 Ciliary protein causing Leber congenital amaurosis disease WEMBL PF05701.11 KFY02067.1 - 9.3 4.8 7.2 1.9 7.1 0.7 2.3 2 1 0 2 2 2 0 Weak chloroplast movement under blue light TFIIA PF03153.13 KFY02068.1 - 8.9 6.2 18.2 11 5.9 18.2 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Pkinase PF00069.25 KFY02069.1 - 0.014 14.8 0.0 0.033 13.6 0.0 1.5 1 1 0 1 1 1 0 Protein kinase domain GP11 PF08677.10 KFY02069.1 - 0.24 10.9 0.0 0.33 10.4 0.0 1.2 1 0 0 1 1 1 0 GP11 baseplate wedge protein UPF0060 PF02694.15 KFY02071.1 - 0.001 19.3 2.1 0.0018 18.5 2.1 1.3 1 0 0 1 1 1 1 Uncharacterised BCR, YnfA/UPF0060 family TcpE PF12648.7 KFY02071.1 - 0.24 11.9 2.1 0.45 11.1 2.1 1.4 1 0 0 1 1 1 0 TcpE family Arteri_Gl PF00951.18 KFY02071.1 - 0.95 9.2 6.3 1.5 8.6 6.3 1.2 1 0 0 1 1 1 0 Arterivirus GL envelope glycoprotein EST1_DNA_bind PF10373.9 KFY02073.1 - 1.5e-05 24.6 5.8 2.1e-05 24.2 0.1 3.1 3 0 0 3 3 3 1 Est1 DNA/RNA binding domain Tudor_RapA PF18337.1 KFY02073.1 - 0.072 13.3 0.1 0.23 11.7 0.1 1.9 2 0 0 2 2 2 0 RapA N-terminal Tudor like domain Prp18 PF02840.15 KFY02100.1 - 5.8e-41 139.9 0.0 5.8e-41 139.9 0.0 2.3 2 1 0 2 2 2 1 Prp18 domain WW PF00397.26 KFY02100.1 - 3.9e-19 68.4 7.3 1.1e-09 38.2 2.8 2.6 2 0 0 2 2 2 2 WW domain CDC27 PF09507.10 KFY02100.1 - 0.63 9.4 27.0 1 8.6 27.0 1.3 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 DUF966 PF06136.13 KFY02100.1 - 0.92 9.2 11.5 1.3 8.6 11.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF966) Kri1_C PF12936.7 KFY02101.1 - 3.4e-32 110.5 0.8 3.4e-32 110.5 0.8 3.3 4 0 0 4 4 4 1 KRI1-like family C-terminal Kri1 PF05178.12 KFY02101.1 - 1.4e-26 93.0 13.7 1.4e-26 93.0 13.7 5.3 5 1 0 5 5 5 1 KRI1-like family Ras PF00071.22 KFY02102.1 - 8.5e-57 191.3 0.0 1e-56 191.0 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFY02102.1 - 2.3e-33 115.0 0.0 3.2e-33 114.5 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFY02102.1 - 1.3e-13 50.7 0.0 1.8e-13 50.4 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KFY02102.1 - 2.1e-05 24.2 0.0 3.1e-05 23.6 0.0 1.3 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 KFY02102.1 - 2.4e-05 23.8 0.0 3.1e-05 23.5 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 KFY02102.1 - 0.00025 21.1 0.0 0.00041 20.4 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.6 KFY02102.1 - 0.0013 19.2 0.6 0.0027 18.1 0.6 1.9 1 1 0 1 1 1 1 AAA ATPase domain RsgA_GTPase PF03193.16 KFY02102.1 - 0.061 13.2 0.1 2.6 7.9 0.0 2.3 2 1 0 2 2 2 0 RsgA GTPase Scs3p PF10261.9 KFY02103.1 - 2.7e-70 236.7 5.6 5.8e-70 235.6 1.7 2.0 2 0 0 2 2 2 2 Inositol phospholipid synthesis and fat-storage-inducing TM DUF2976 PF11190.8 KFY02105.1 - 0.029 14.1 0.1 0.066 13.0 0.1 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2976) WD40 PF00400.32 KFY02106.1 - 2e-44 148.7 27.9 3.2e-08 34.1 0.5 6.9 6 1 0 6 6 6 6 WD domain, G-beta repeat TFIID_NTD2 PF04494.15 KFY02106.1 - 7.9e-40 136.1 0.9 1.2e-39 135.5 0.9 1.3 1 0 0 1 1 1 1 WD40 associated region in TFIID subunit, NTD2 domain ANAPC4_WD40 PF12894.7 KFY02106.1 - 7e-10 39.1 1.2 0.27 11.6 0.1 5.1 2 1 3 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KFY02106.1 - 1.1e-05 24.4 0.1 0.037 12.7 0.0 3.1 3 0 0 3 3 3 2 Nucleoporin Nup120/160 LisH PF08513.11 KFY02106.1 - 4.1e-05 23.4 0.0 9e-05 22.3 0.0 1.6 1 0 0 1 1 1 1 LisH Nucleoporin_N PF08801.11 KFY02106.1 - 0.00056 18.8 0.2 0.72 8.5 0.0 3.5 2 2 1 4 4 4 1 Nup133 N terminal like RAB3GAP2_N PF14655.6 KFY02106.1 - 0.00085 18.7 0.0 3.9 6.6 0.0 3.3 2 1 1 3 3 3 2 Rab3 GTPase-activating protein regulatory subunit N-terminus Ge1_WD40 PF16529.5 KFY02106.1 - 0.01 14.9 2.0 11 4.9 0.1 3.6 3 1 0 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Med11 PF10280.9 KFY02107.1 - 2.4e-41 141.4 0.4 3e-41 141.1 0.4 1.1 1 0 0 1 1 1 1 Mediator complex protein Vps5 PF09325.10 KFY02108.1 - 1.2e-85 286.8 2.2 1.2e-85 286.8 2.2 1.5 2 0 0 2 2 2 1 Vps5 C terminal like PX PF00787.24 KFY02108.1 - 2.7e-24 85.3 0.0 5.8e-24 84.2 0.0 1.6 1 0 0 1 1 1 1 PX domain BAR_2 PF10455.9 KFY02108.1 - 0.0096 15.1 0.5 0.016 14.4 0.5 1.3 1 0 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking BAR_3 PF16746.5 KFY02108.1 - 0.016 14.9 3.3 0.24 11.1 0.6 2.4 1 1 1 2 2 2 0 BAR domain of APPL family Ribosomal_L31 PF01197.18 KFY02109.1 - 0.00013 22.1 0.0 0.00024 21.3 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L31 Flavin_Reduct PF01613.18 KFY02110.1 - 1.1e-24 87.2 0.0 1.6e-24 86.7 0.0 1.2 1 0 0 1 1 1 1 Flavin reductase like domain HSP90 PF00183.18 KFY02111.1 - 1.5e-219 730.2 27.5 1.9e-219 729.9 27.5 1.0 1 0 0 1 1 1 1 Hsp90 protein HATPase_c PF02518.26 KFY02111.1 - 1.9e-14 54.1 0.1 3.6e-14 53.2 0.1 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 KFY02111.1 - 6.7e-09 35.7 0.1 2.2e-08 34.0 0.1 1.9 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF1676 PF07898.13 KFY02111.1 - 0.55 10.2 6.1 0.69 9.9 0.3 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1676) SSrecog PF03531.14 KFY02112.1 - 7.2e-31 105.9 0.2 1.1e-29 102.2 0.0 2.9 3 0 0 3 3 3 1 Structure-specific recognition protein (SSRP1) POB3_N PF17292.2 KFY02112.1 - 1.6e-29 102.1 1.3 9.2e-29 99.7 0.6 2.5 3 0 0 3 3 3 1 POB3-like N-terminal PH domain Rtt106 PF08512.12 KFY02112.1 - 4.9e-24 84.6 0.1 6.9e-23 80.9 0.0 2.7 3 0 0 3 3 3 1 Histone chaperone Rttp106-like Pkinase PF00069.25 KFY02113.1 - 2.6e-76 256.5 0.0 3e-76 256.3 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFY02113.1 - 1.8e-35 122.5 0.0 2.3e-35 122.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 KFY02113.1 - 0.00019 20.5 0.0 0.0018 17.3 0.0 2.2 1 1 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 KFY02113.1 - 0.083 12.8 0.1 0.16 11.8 0.1 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kinase-like PF14531.6 KFY02113.1 - 0.18 11.1 0.0 0.39 10.0 0.0 1.7 2 0 0 2 2 2 0 Kinase-like DNA_pol_phi PF04931.13 KFY02132.1 - 6.9 4.6 7.5 8 4.4 7.5 1.1 1 0 0 1 1 1 0 DNA polymerase phi Actin PF00022.19 KFY02140.1 - 6.7e-123 410.3 0.0 4.3e-122 407.6 0.0 1.8 1 1 0 1 1 1 1 Actin Pkinase PF00069.25 KFY02142.1 - 2.4e-74 250.0 0.0 3.5e-74 249.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFY02142.1 - 6.4e-39 133.8 0.0 9.1e-39 133.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase AdenylateSensor PF16579.5 KFY02142.1 - 5.2e-22 78.5 0.0 1.7e-09 38.2 0.0 2.7 2 0 0 2 2 2 2 Adenylate sensor of SNF1-like protein kinase UBA_2 PF08587.11 KFY02142.1 - 1.9e-15 56.7 0.1 4.5e-15 55.5 0.1 1.7 1 0 0 1 1 1 1 Ubiquitin associated domain (UBA) Kinase-like PF14531.6 KFY02142.1 - 1.5e-06 27.8 0.0 2.2e-06 27.2 0.0 1.3 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.22 KFY02142.1 - 0.00016 21.3 0.5 0.00029 20.5 0.5 1.3 1 0 0 1 1 1 1 RIO1 family Haspin_kinase PF12330.8 KFY02142.1 - 0.00049 19.2 0.2 0.0011 18.0 0.2 1.6 1 0 0 1 1 1 1 Haspin like kinase domain YukC PF10140.9 KFY02142.1 - 0.011 14.5 0.2 0.017 14.0 0.2 1.2 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukC Kdo PF06293.14 KFY02142.1 - 0.013 14.8 0.2 0.025 14.0 0.2 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KFY02142.1 - 0.068 13.1 0.3 0.38 10.6 0.0 2.4 3 0 0 3 3 3 0 Phosphotransferase enzyme family NDUFA12 PF05071.16 KFY02143.1 - 1.7e-12 48.0 0.1 4.6e-12 46.6 0.1 1.7 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase subunit NDUFA12 Hemopexin PF00045.19 KFY02143.1 - 0.13 12.3 0.1 0.26 11.3 0.1 1.5 1 0 0 1 1 1 0 Hemopexin AKNA PF12443.8 KFY02157.1 - 0.37 11.5 2.6 0.52 11.0 0.2 2.5 2 0 0 2 2 2 0 AT-hook-containing transcription factor HAD_2 PF13419.6 KFY02158.1 - 2.2e-12 47.4 0.0 2.7e-12 47.2 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KFY02158.1 - 3.4e-09 37.3 0.0 3.5e-08 34.0 0.0 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KFY02158.1 - 0.021 14.9 0.0 0.032 14.3 0.0 1.3 1 0 0 1 1 1 0 HAD-hyrolase-like DUF4437 PF14499.6 KFY02158.1 - 0.19 10.8 0.0 0.28 10.3 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4437) ABC_tran PF00005.27 KFY02178.1 - 4.3e-34 118.0 0.0 1.2e-33 116.6 0.0 1.8 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.23 KFY02178.1 - 1.2e-33 116.9 7.9 1.6e-33 116.5 7.9 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region SMC_N PF02463.19 KFY02178.1 - 4.7e-08 32.7 2.7 6.2e-07 29.1 2.7 2.8 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 KFY02178.1 - 0.0023 18.3 0.1 0.0096 16.3 0.1 2.0 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 KFY02178.1 - 0.0062 16.8 0.3 0.056 13.7 0.3 2.2 1 1 0 1 1 1 1 AAA domain SbcCD_C PF13558.6 KFY02178.1 - 0.0079 16.4 0.3 0.12 12.6 0.3 2.5 1 1 0 1 1 1 1 Putative exonuclease SbcCD, C subunit RsgA_GTPase PF03193.16 KFY02178.1 - 0.019 14.9 0.0 0.044 13.7 0.0 1.6 1 0 0 1 1 1 0 RsgA GTPase AAA_29 PF13555.6 KFY02178.1 - 0.028 14.2 0.1 0.063 13.0 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_23 PF13476.6 KFY02178.1 - 0.16 12.5 0.4 0.38 11.2 0.0 1.7 2 0 0 2 2 2 0 AAA domain Pyr_redox_2 PF07992.14 KFY02179.1 - 2.5e-52 177.9 0.1 3.1e-52 177.6 0.1 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KFY02179.1 - 8.5e-13 48.7 0.0 1.1e-10 41.9 0.1 2.7 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KFY02179.1 - 0.00044 19.6 0.2 0.69 9.1 0.0 2.7 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KFY02179.1 - 1.8 7.2 4.6 0.94 8.1 0.1 2.4 2 1 1 3 3 3 0 HI0933-like protein Acetyltransf_1 PF00583.25 KFY02180.1 - 8.2e-09 35.7 0.0 2e-08 34.5 0.0 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KFY02180.1 - 1.5e-08 34.6 0.0 2.7e-08 33.8 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KFY02180.1 - 3.3e-08 33.9 0.0 1.1e-07 32.1 0.1 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KFY02180.1 - 2.5e-05 24.2 0.0 4.1e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.7 KFY02180.1 - 0.0017 18.5 0.0 0.27 11.3 0.0 2.3 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 KFY02180.1 - 0.0037 17.4 0.0 0.0056 16.8 0.0 1.3 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase End_beta_barrel PF12195.8 KFY02181.1 - 0.052 13.5 0.1 0.2 11.7 0.1 2.0 1 0 0 1 1 1 0 Beta barrel domain of bacteriophage endosialidase NOA36 PF06524.12 KFY02181.1 - 4.2 6.6 13.2 0.28 10.4 5.0 2.3 2 0 0 2 2 2 0 NOA36 protein DUF4620 PF15399.6 KFY02181.1 - 7.8 6.9 18.5 0.15 12.4 5.7 3.5 2 1 1 3 3 3 0 Domain of unknown function (DUF4620) Glyco_transf_54 PF04666.13 KFY02182.1 - 1.2e-10 40.7 0.2 1.6e-09 37.1 0.2 2.1 1 1 0 1 1 1 1 N-Acetylglucosaminyltransferase-IV (GnT-IV) conserved region CDC45 PF02724.14 KFY02182.1 - 1.2 7.3 4.8 1.7 6.8 4.8 1.1 1 0 0 1 1 1 0 CDC45-like protein Tho2 PF11262.8 KFY02182.1 - 1.7 7.8 8.6 2.7 7.1 8.6 1.2 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 LANC_like PF05147.13 KFY02185.1 - 8.5e-21 73.9 0.0 3e-20 72.1 0.0 1.9 1 1 0 1 1 1 1 Lanthionine synthetase C-like protein Abhydrolase_6 PF12697.7 KFY02186.1 - 1.8e-20 74.5 1.4 2.1e-20 74.3 1.4 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family HTH_20 PF12840.7 KFY02187.1 - 0.16 12.1 0.0 9 6.4 0.0 3.3 3 0 0 3 3 3 0 Helix-turn-helix domain DUF3328 PF11807.8 KFY02194.1 - 7.2e-52 176.3 0.0 9.3e-52 176.0 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) AFG1_ATPase PF03969.16 KFY02197.1 - 5.7e-98 328.1 0.0 4.6e-93 312.0 0.0 2.3 2 0 0 2 2 2 2 AFG1-like ATPase Hist_deacetyl PF00850.19 KFY02197.1 - 1.4e-53 182.4 0.1 2.2e-53 181.7 0.1 1.3 1 0 0 1 1 1 1 Histone deacetylase domain AAA_16 PF13191.6 KFY02197.1 - 0.0024 18.3 0.0 0.43 10.9 0.0 3.0 3 0 0 3 3 3 1 AAA ATPase domain AAA_22 PF13401.6 KFY02197.1 - 0.074 13.3 0.0 0.23 11.7 0.0 1.9 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 KFY02197.1 - 0.12 12.4 0.0 0.24 11.4 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_5 PF07728.14 KFY02197.1 - 0.13 12.3 0.0 0.27 11.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Bac_DnaA PF00308.18 KFY02197.1 - 0.26 11.1 0.2 19 5.0 0.1 2.4 2 1 0 2 2 2 0 Bacterial dnaA protein RIBIOP_C PF04950.12 KFY02198.1 - 9.7e-93 310.8 0.1 9.7e-93 310.8 0.1 1.6 2 0 0 2 2 1 1 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal AARP2CN PF08142.12 KFY02198.1 - 4.9e-29 100.3 0.0 1.2e-28 99.0 0.0 1.8 1 0 0 1 1 1 1 AARP2CN (NUC121) domain AAA_22 PF13401.6 KFY02198.1 - 9e-06 26.0 0.0 2.4e-05 24.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KFY02198.1 - 5e-05 23.8 0.0 0.00016 22.1 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain AAA_33 PF13671.6 KFY02198.1 - 0.00013 22.1 0.7 0.00046 20.4 0.0 2.2 2 0 0 2 2 2 1 AAA domain GTP_EFTU PF00009.27 KFY02198.1 - 0.00017 21.2 0.0 0.079 12.5 0.0 2.4 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain NACHT PF05729.12 KFY02198.1 - 0.00022 21.2 0.0 0.00045 20.2 0.0 1.6 1 0 0 1 1 1 1 NACHT domain MMR_HSR1 PF01926.23 KFY02198.1 - 0.00034 20.7 0.0 0.0011 19.0 0.0 1.9 1 0 0 1 1 1 1 50S ribosome-binding GTPase ABC_tran PF00005.27 KFY02198.1 - 0.00051 20.6 0.4 0.0019 18.7 0.0 2.2 2 0 0 2 2 1 1 ABC transporter AAA PF00004.29 KFY02198.1 - 0.00071 20.0 0.0 0.0018 18.7 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) PduV-EutP PF10662.9 KFY02198.1 - 0.0013 18.5 0.0 0.0043 16.8 0.0 1.7 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation AAA_19 PF13245.6 KFY02198.1 - 0.0054 17.1 0.0 0.012 15.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 KFY02198.1 - 0.0057 17.2 7.5 0.0078 16.8 0.0 3.4 3 0 0 3 3 2 1 AAA domain AAA_30 PF13604.6 KFY02198.1 - 0.0073 16.0 0.0 0.016 14.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain Roc PF08477.13 KFY02198.1 - 0.0092 16.2 0.0 0.083 13.1 0.0 2.4 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase NB-ARC PF00931.22 KFY02198.1 - 0.011 14.9 0.0 0.032 13.4 0.0 1.7 2 0 0 2 2 2 0 NB-ARC domain RNA_helicase PF00910.22 KFY02198.1 - 0.019 15.3 0.0 0.044 14.2 0.0 1.6 1 0 0 1 1 1 0 RNA helicase Rad17 PF03215.15 KFY02198.1 - 0.019 14.9 0.0 0.1 12.5 0.0 2.0 2 0 0 2 2 2 0 Rad17 P-loop domain AAA_28 PF13521.6 KFY02198.1 - 0.019 15.2 3.1 0.029 14.6 0.0 2.8 3 0 0 3 3 3 0 AAA domain Ploopntkinase3 PF18751.1 KFY02198.1 - 0.022 14.6 0.0 0.05 13.5 0.0 1.5 1 0 0 1 1 1 0 P-loop Nucleotide Kinase3 cobW PF02492.19 KFY02198.1 - 0.03 13.9 0.0 0.059 13.0 0.0 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_14 PF13173.6 KFY02198.1 - 0.032 14.3 0.0 0.083 12.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 KFY02198.1 - 0.055 13.4 0.0 0.13 12.2 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase AAA_5 PF07728.14 KFY02198.1 - 0.067 13.2 0.0 0.2 11.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_25 PF13481.6 KFY02198.1 - 0.085 12.4 0.0 0.22 11.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 KFY02198.1 - 0.16 11.5 0.0 0.32 10.5 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_21 PF13304.6 KFY02198.1 - 3.1 7.5 6.3 4.8 6.9 0.0 2.6 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system AATF-Che1 PF13339.6 KFY02198.1 - 5.6 7.7 10.2 0.36 11.5 4.1 2.2 2 0 0 2 2 1 0 Apoptosis antagonizing transcription factor Ribosomal_L13e PF01294.18 KFY02203.1 - 5.8e-75 251.1 5.8 5.8e-75 251.1 5.8 1.3 2 0 0 2 2 2 1 Ribosomal protein L13e Hormone_2 PF00123.20 KFY02203.1 - 0.17 11.8 2.0 0.38 10.7 2.0 1.6 1 0 0 1 1 1 0 Peptide hormone DUF702 PF05142.12 KFY02204.1 - 0.61 10.6 8.1 25 5.4 0.5 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF702) Viral_NABP PF05515.11 KFY02204.1 - 9.1 6.1 9.7 3.3 7.5 0.3 2.9 3 0 0 3 3 3 0 Viral nucleic acid binding Amidoligase_2 PF12224.8 KFY02205.1 - 1.7e-14 54.1 0.0 2.4e-14 53.6 0.0 1.2 1 0 0 1 1 1 1 Putative amidoligase enzyme Abhydrolase_1 PF00561.20 KFY02207.1 - 2e-22 80.1 0.1 1.9e-17 63.8 0.1 2.3 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_4 PF08386.10 KFY02207.1 - 6.5e-21 74.4 0.0 1.3e-20 73.5 0.0 1.5 1 0 0 1 1 1 1 TAP-like protein FA_hydroxylase PF04116.13 KFY02208.1 - 1.5e-20 73.9 12.7 1.5e-20 73.9 12.7 2.0 2 1 0 2 2 2 1 Fatty acid hydroxylase superfamily Fructosamin_kin PF03881.14 KFY02208.1 - 0.14 11.4 0.0 0.26 10.4 0.0 1.4 1 0 0 1 1 1 0 Fructosamine kinase Hexapep PF00132.24 KFY02209.1 - 6.1e-16 57.4 17.3 1.1e-11 44.0 4.2 4.1 3 1 0 3 3 3 2 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 KFY02209.1 - 5.5e-14 51.6 9.5 6.4e-08 32.2 4.5 3.6 3 1 0 3 3 3 2 Hexapeptide repeat of succinyl-transferase Mac PF12464.8 KFY02209.1 - 1.4e-07 31.6 0.1 2.6e-07 30.7 0.1 1.5 1 0 0 1 1 1 1 Maltose acetyltransferase NolB PF17398.2 KFY02209.1 - 0.079 13.4 0.0 0.13 12.7 0.0 1.3 1 0 0 1 1 1 0 Nodulation protein NolB Glyco_hydro_1 PF00232.18 KFY02210.1 - 3.9e-101 338.7 0.0 4.7e-101 338.5 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 1 TruD PF01142.18 KFY02211.1 - 3.8e-63 213.7 0.2 1.8e-57 195.0 0.0 4.2 3 1 0 3 3 3 3 tRNA pseudouridine synthase D (TruD) SAD_SRA PF02182.17 KFY02211.1 - 0.0015 18.2 0.0 0.0044 16.7 0.0 1.9 1 1 0 1 1 1 1 SAD/SRA domain HsbA PF12296.8 KFY02213.1 - 1.3e-06 28.8 0.0 1.9e-06 28.3 0.0 1.2 1 0 0 1 1 1 1 Hydrophobic surface binding protein A adh_short PF00106.25 KFY02214.1 - 4.1e-28 98.2 0.2 3.1e-21 75.7 0.1 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KFY02214.1 - 1.7e-16 60.5 0.1 8.1e-16 58.3 0.1 1.8 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KFY02214.1 - 4e-06 26.8 0.1 1.9e-05 24.7 0.0 1.9 2 0 0 2 2 2 1 KR domain Epimerase PF01370.21 KFY02214.1 - 0.025 14.0 0.0 0.039 13.4 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Queuosine_synth PF02547.15 KFY02214.1 - 0.067 12.3 0.0 0.32 10.1 0.0 1.9 1 1 0 1 1 1 0 Queuosine biosynthesis protein Zn_clus PF00172.18 KFY02215.1 - 4.6e-07 29.8 10.0 4.6e-07 29.8 10.0 2.1 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain COG7 PF10191.9 KFY02215.1 - 0.14 10.4 0.6 0.2 9.8 0.6 1.1 1 0 0 1 1 1 0 Golgi complex component 7 (COG7) YaaC PF14175.6 KFY02216.1 - 0.041 13.1 0.1 0.054 12.7 0.1 1.2 1 0 0 1 1 1 0 YaaC-like Protein adh_short PF00106.25 KFY02217.1 - 2.2e-32 112.1 0.0 1.6e-25 89.7 0.1 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KFY02217.1 - 1.4e-21 77.2 0.0 7.3e-15 55.2 0.1 2.0 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KFY02217.1 - 5.3e-09 36.2 0.1 7.8e-09 35.7 0.1 1.2 1 0 0 1 1 1 1 KR domain TIR PF01582.20 KFY02217.1 - 0.11 12.3 0.1 0.16 11.7 0.1 1.2 1 0 0 1 1 1 0 TIR domain DUF3176 PF11374.8 KFY02218.1 - 0.018 15.2 1.5 0.018 15.2 1.5 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF3176) DUF2275 PF10039.9 KFY02218.1 - 0.041 14.0 0.0 0.63 10.1 0.0 2.2 2 0 0 2 2 2 0 Predicted integral membrane protein (DUF2275) HTH_psq PF05225.16 KFY02219.1 - 6.6e-05 22.6 0.5 0.00015 21.4 0.1 1.9 2 0 0 2 2 2 1 helix-turn-helix, Psq domain CENP-B_N PF04218.13 KFY02219.1 - 0.014 15.0 0.4 0.057 13.1 0.0 2.2 2 0 0 2 2 2 0 CENP-B N-terminal DNA-binding domain ADH_N PF08240.12 KFY02220.1 - 1.1e-21 76.8 5.7 1.9e-21 76.0 5.7 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KFY02220.1 - 1.4e-17 63.9 0.0 2.5e-17 63.1 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 KFY02220.1 - 0.00016 21.1 0.1 0.00027 20.4 0.1 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 KFY02220.1 - 0.0029 16.9 0.1 0.0055 16.0 0.1 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain ThiF PF00899.21 KFY02220.1 - 0.019 14.3 0.3 0.038 13.3 0.3 1.4 1 0 0 1 1 1 0 ThiF family 3HCDH_N PF02737.18 KFY02220.1 - 0.044 13.7 0.0 0.067 13.1 0.0 1.2 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain PhzC-PhzF PF02567.16 KFY02221.1 - 1.6e-38 132.8 0.1 2.6e-38 132.1 0.1 1.3 1 1 0 1 1 1 1 Phenazine biosynthesis-like protein Amidohydro_3 PF07969.11 KFY02222.1 - 2.8e-70 238.1 0.3 3.2e-70 237.9 0.3 1.0 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_1 PF01979.20 KFY02222.1 - 3.3e-10 39.8 0.3 3.5e-06 26.6 0.1 2.5 2 1 0 2 2 2 2 Amidohydrolase family HlyIII PF03006.20 KFY02224.1 - 4.5e-54 183.5 18.3 5.5e-54 183.3 18.3 1.1 1 0 0 1 1 1 1 Haemolysin-III related Isochorismatase PF00857.20 KFY02225.1 - 1.9e-18 67.2 0.0 3e-18 66.6 0.0 1.3 1 0 0 1 1 1 1 Isochorismatase family Cytochrom_B561 PF03188.16 KFY02225.1 - 4.2e-08 33.4 9.2 7.1e-08 32.7 9.2 1.4 1 0 0 1 1 1 1 Eukaryotic cytochrome b561 DUF2427 PF10348.9 KFY02225.1 - 5.6e-07 29.3 3.1 1.3e-06 28.1 3.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF2427) DUF4079 PF13301.6 KFY02225.1 - 1.9 8.6 11.2 0.49 10.6 5.4 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF4079) Fungal_trans PF04082.18 KFY02226.1 - 1.2e-05 24.5 0.8 3.2e-05 23.1 0.8 1.7 1 1 0 1 1 1 1 Fungal specific transcription factor domain Prion PF00377.18 KFY02226.1 - 0.046 13.6 0.0 0.2 11.5 0.0 1.9 2 0 0 2 2 2 0 Prion/Doppel alpha-helical domain DUF4441 PF14536.6 KFY02226.1 - 0.12 12.6 0.2 0.32 11.2 0.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4441) DUF2263 PF10021.9 KFY02227.1 - 3.1e-23 82.8 0.0 6e-23 81.8 0.0 1.5 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2263) Macro PF01661.21 KFY02227.1 - 0.002 18.2 0.0 0.0037 17.3 0.0 1.5 1 0 0 1 1 1 1 Macro domain Zip PF02535.22 KFY02229.1 - 1.3e-50 172.5 2.5 1.6e-50 172.3 2.5 1.0 1 0 0 1 1 1 1 ZIP Zinc transporter OrsD PF12013.8 KFY02230.1 - 1.2e-08 35.4 0.2 3.1e-08 34.1 0.1 1.8 2 0 0 2 2 2 1 Orsellinic acid/F9775 biosynthesis cluster protein D Fungal_trans_2 PF11951.8 KFY02230.1 - 6.2e-06 25.3 0.2 1.1e-05 24.5 0.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain p450 PF00067.22 KFY02231.1 - 1.5e-69 235.0 0.0 1.8e-69 234.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 AXE1 PF05448.12 KFY02232.1 - 1.7e-05 23.6 0.0 6.6e-05 21.7 0.0 1.8 2 0 0 2 2 2 1 Acetyl xylan esterase (AXE1) Abhydrolase_6 PF12697.7 KFY02232.1 - 7.1e-05 23.5 0.1 0.00011 22.9 0.1 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 KFY02232.1 - 7.6e-05 22.3 0.0 0.00048 19.7 0.0 1.9 2 0 0 2 2 2 1 Prolyl oligopeptidase family DUF1100 PF06500.11 KFY02232.1 - 0.00013 20.9 0.0 0.00021 20.2 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1100) Peptidase_S15 PF02129.18 KFY02232.1 - 0.00034 20.3 0.0 0.0014 18.3 0.0 1.8 2 0 0 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) Hydrolase_4 PF12146.8 KFY02232.1 - 0.00036 19.9 0.0 0.0036 16.6 0.0 2.0 2 0 0 2 2 2 1 Serine aminopeptidase, S33 BAAT_C PF08840.11 KFY02232.1 - 0.0015 18.5 0.0 0.0029 17.5 0.0 1.5 1 0 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_1 PF00561.20 KFY02232.1 - 0.009 15.7 0.0 0.015 15.0 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Anth_synt_I_N PF04715.13 KFY02234.1 - 1.5e-24 86.9 0.0 9.3e-24 84.3 0.0 2.2 1 1 1 2 2 2 1 Anthranilate synthase component I, N terminal region Chorismate_bind PF00425.18 KFY02234.1 - 0.0022 17.6 0.0 0.96 9.0 0.0 2.2 2 0 0 2 2 2 2 chorismate binding enzyme DUF2203 PF09969.9 KFY02235.1 - 0.0022 18.7 4.8 0.0048 17.6 4.8 1.6 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2203) DinB PF05163.12 KFY02235.1 - 1.9 8.4 7.0 0.13 12.2 0.5 2.2 2 1 0 3 3 3 0 DinB family Sugar_tr PF00083.24 KFY02236.1 - 7.9e-89 298.6 29.4 9.7e-89 298.3 29.4 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KFY02236.1 - 8.8e-21 74.2 58.1 2.4e-20 72.8 27.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DNAPolymera_Pol PF11590.8 KFY02236.1 - 0.075 12.9 0.2 0.38 10.7 0.2 2.3 1 0 0 1 1 1 0 DNA polymerase catalytic subunit Pol Ribul_P_3_epim PF00834.19 KFY02238.1 - 2.6e-60 203.2 0.0 2.2e-59 200.2 0.0 1.9 1 1 0 1 1 1 1 Ribulose-phosphate 3 epimerase family QRPTase_C PF01729.19 KFY02238.1 - 0.13 12.0 0.0 0.2 11.4 0.0 1.3 1 0 0 1 1 1 0 Quinolinate phosphoribosyl transferase, C-terminal domain Pkinase PF00069.25 KFY02240.1 - 8.2e-23 81.1 0.0 9.6e-23 80.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFY02240.1 - 6.2e-20 71.6 0.0 9.9e-20 70.9 0.0 1.2 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KFY02240.1 - 1.3e-05 24.7 0.0 2e-05 24.0 0.0 1.2 1 0 0 1 1 1 1 Kinase-like TrkH PF02386.16 KFY02241.1 - 5.3e-103 345.1 3.8 1.1e-98 330.9 0.5 2.1 2 0 0 2 2 2 2 Cation transport protein HAD_2 PF13419.6 KFY02242.1 - 6.1e-27 94.8 0.0 7.4e-27 94.6 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KFY02242.1 - 2e-13 51.1 0.2 1.9e-12 47.9 0.2 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 KFY02242.1 - 1.6e-11 45.0 0.0 2.2e-11 44.5 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KFY02242.1 - 1.3e-10 41.2 0.0 2.6e-10 40.2 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase_6 PF13344.6 KFY02242.1 - 2.3e-05 24.4 0.0 0.016 15.3 0.0 2.5 3 0 0 3 3 3 2 Haloacid dehalogenase-like hydrolase Acid_PPase PF12689.7 KFY02242.1 - 0.0031 17.4 0.0 4.1 7.2 0.0 3.0 3 0 0 3 3 3 2 Acid Phosphatase PGP_phosphatase PF09419.10 KFY02242.1 - 0.027 14.1 0.0 0.14 11.8 0.0 2.0 2 0 0 2 2 2 0 Mitochondrial PGP phosphatase Hydrolase_3 PF08282.12 KFY02242.1 - 0.14 11.9 0.5 0.99 9.1 0.2 2.4 2 1 0 2 2 2 0 haloacid dehalogenase-like hydrolase GPI-anchored PF10342.9 KFY02244.1 - 0.0024 18.6 0.1 0.0076 17.0 0.1 1.9 1 1 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family WSC PF01822.19 KFY02245.1 - 1.4e-14 54.0 7.0 3.2e-14 52.9 7.0 1.7 1 0 0 1 1 1 1 WSC domain FAD_binding_4 PF01565.23 KFY02248.1 - 3.3e-29 101.4 0.7 5.7e-29 100.6 0.7 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 KFY02248.1 - 4e-10 39.6 0.0 8.5e-10 38.6 0.0 1.6 1 0 0 1 1 1 1 Berberine and berberine like p450 PF00067.22 KFY02249.1 - 5.9e-60 203.3 0.0 7.4e-60 203.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 NAD_binding_1 PF00175.21 KFY02250.1 - 1.2e-30 106.3 0.0 2.3e-30 105.4 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 KFY02250.1 - 2.9e-30 104.5 0.0 5.2e-30 103.7 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain Cyt-b5 PF00173.28 KFY02250.1 - 6.8e-22 77.4 0.0 1.5e-21 76.3 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain NAD_binding_6 PF08030.12 KFY02250.1 - 0.0018 18.4 0.0 0.021 14.9 0.0 2.2 2 0 0 2 2 2 1 Ferric reductase NAD binding domain 3HCDH_N PF02737.18 KFY02251.1 - 6.8e-31 107.5 0.0 1.6e-30 106.3 0.0 1.6 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.22 KFY02251.1 - 2.5e-17 63.2 0.0 1e-16 61.3 0.0 1.9 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain NHL PF01436.21 KFY02251.1 - 0.0021 18.0 0.0 0.11 12.5 0.0 3.5 4 0 0 4 4 4 1 NHL repeat NAD_binding_2 PF03446.15 KFY02251.1 - 0.0097 16.1 0.0 0.015 15.4 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_Gly3P_dh_N PF01210.23 KFY02251.1 - 0.03 14.3 0.0 0.05 13.6 0.0 1.3 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus ApbA PF02558.16 KFY02251.1 - 0.054 13.1 0.0 0.21 11.2 0.0 1.9 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA Antimicrobial19 PF08225.11 KFY02251.1 - 0.34 10.5 0.9 0.68 9.6 0.9 1.5 1 0 0 1 1 1 0 Pseudin antimicrobial peptide Ldl_recept_b PF00058.17 KFY02251.1 - 0.57 10.7 2.3 13 6.4 0.0 3.8 5 0 0 5 5 5 0 Low-density lipoprotein receptor repeat class B RhoGAP PF00620.27 KFY02252.1 - 7.4e-35 120.0 0.0 1.4e-34 119.1 0.0 1.4 1 0 0 1 1 1 1 RhoGAP domain LIM PF00412.22 KFY02252.1 - 1.1e-32 112.0 38.7 1.3e-11 44.5 6.6 5.0 5 0 0 5 5 5 4 LIM domain Spt20 PF12090.8 KFY02252.1 - 5.1 6.6 9.6 15 5.1 9.6 1.7 1 0 0 1 1 1 0 Spt20 family Desulfoferrod_N PF06397.12 KFY02252.1 - 8 6.2 6.5 0.44 10.2 0.1 2.3 3 0 0 3 3 3 0 Desulfoferrodoxin, N-terminal domain UQ_con PF00179.26 KFY02253.1 - 1.7e-40 137.9 0.0 2.3e-29 101.8 0.0 2.2 2 0 0 2 2 2 2 Ubiquitin-conjugating enzyme UEV PF05743.13 KFY02253.1 - 0.029 14.2 0.0 0.06 13.2 0.0 1.5 1 0 0 1 1 1 0 UEV domain Pkinase PF00069.25 KFY02254.1 - 3.4e-62 210.2 0.0 1.1e-38 133.2 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 KFY02254.1 - 4.1e-27 95.1 0.0 9.2e-20 71.0 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Response_reg PF00072.24 KFY02254.1 - 1.7e-12 47.5 0.0 3.2e-12 46.6 0.0 1.4 1 0 0 1 1 1 1 Response regulator receiver domain Kinase-like PF14531.6 KFY02254.1 - 9e-08 31.8 0.1 2e-05 24.0 0.0 2.8 3 0 0 3 3 3 2 Kinase-like APH PF01636.23 KFY02254.1 - 1.5e-05 25.1 1.5 0.0032 17.4 0.1 3.4 2 1 1 3 3 3 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 KFY02254.1 - 0.0076 15.2 0.0 0.013 14.4 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 KFY02254.1 - 0.019 14.3 0.0 0.034 13.5 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family PAS_9 PF13426.7 KFY02254.1 - 0.1 12.9 0.0 0.27 11.5 0.0 1.7 1 0 0 1 1 1 0 PAS domain Seadorna_VP7 PF07387.11 KFY02254.1 - 0.17 10.9 0.1 0.28 10.2 0.1 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Ank_5 PF13857.6 KFY02256.1 - 4.8e-21 74.5 0.7 5.7e-06 26.5 0.1 4.0 3 1 1 4 4 4 4 Ankyrin repeats (many copies) Ank_2 PF12796.7 KFY02256.1 - 6.1e-20 71.6 0.0 3.2e-10 40.5 0.0 2.3 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KFY02256.1 - 9.2e-18 62.5 0.0 0.0003 21.0 0.0 4.3 4 0 0 4 4 4 4 Ankyrin repeat Ank_4 PF13637.6 KFY02256.1 - 5e-15 55.7 0.0 3.7e-06 27.4 0.0 2.7 2 1 0 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 KFY02256.1 - 1.8e-14 53.4 0.0 0.00035 20.9 0.0 4.2 4 0 0 4 4 4 3 Ankyrin repeat HA PF03457.14 KFY02256.1 - 0.041 14.2 0.0 3.5 8.0 0.0 2.9 2 1 1 3 3 3 0 Helicase associated domain Pkinase PF00069.25 KFY02259.1 - 5.9e-72 242.2 0.0 7.8e-72 241.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFY02259.1 - 1.7e-43 148.8 0.0 2.3e-43 148.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KFY02259.1 - 1.9e-09 37.2 0.0 3.6e-09 36.4 0.0 1.5 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.14 KFY02259.1 - 0.00018 20.9 0.1 0.00033 20.1 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 KFY02259.1 - 0.0064 15.5 0.1 0.0098 14.9 0.1 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Pkinase_fungal PF17667.1 KFY02259.1 - 0.0097 14.7 0.1 0.0097 14.7 0.1 2.1 2 0 0 2 2 2 1 Fungal protein kinase OPA3 PF07047.12 KFY02260.1 - 1.1e-40 138.3 8.4 1.1e-40 138.3 8.4 1.5 1 1 0 1 1 1 1 Optic atrophy 3 protein (OPA3) HSP90 PF00183.18 KFY02260.1 - 0.0022 17.0 0.1 0.0022 17.0 0.1 1.5 2 0 0 2 2 2 1 Hsp90 protein DUF4795 PF16043.5 KFY02260.1 - 5.1 6.6 11.8 3.5 7.2 1.5 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4795) DUF4140 PF13600.6 KFY02260.1 - 6.6 7.2 13.8 7.5 7.1 3.0 3.0 2 1 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) SBDS PF01172.18 KFY02264.1 - 8.2e-26 89.9 0.6 9.6e-26 89.7 0.6 1.0 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein HsdM_N PF12161.8 KFY02264.1 - 0.071 13.7 0.1 0.086 13.5 0.1 1.1 1 0 0 1 1 1 0 HsdM N-terminal domain RhoGEF PF00621.20 KFY02265.1 - 6.5e-23 81.9 0.0 1.1e-22 81.2 0.0 1.4 1 0 0 1 1 1 1 RhoGEF domain CSRNP_N PF16019.5 KFY02265.1 - 0.14 12.1 1.2 0.26 11.2 1.2 1.4 1 0 0 1 1 1 0 Cysteine/serine-rich nuclear protein N-terminus DEAD PF00270.29 KFY02266.1 - 1.8e-46 158.1 0.0 4.9e-46 156.7 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KFY02266.1 - 1.3e-28 99.5 0.0 7.7e-28 97.1 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KFY02266.1 - 0.00094 19.2 0.0 0.0022 18.1 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DUF3334 PF11813.8 KFY02266.1 - 0.2 11.4 0.0 0.37 10.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3334) DUF4355 PF14265.6 KFY02266.1 - 5.8 7.2 11.2 20 5.5 11.2 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4355) MFAP1 PF06991.11 KFY02266.1 - 6.7 6.5 19.0 6.2 6.6 8.7 3.4 3 0 0 3 3 3 0 Microfibril-associated/Pre-mRNA processing DUF2986 PF11661.8 KFY02266.1 - 9.8 6.8 8.4 1.1 9.8 2.5 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2986) Mitoc_mL59 PF18126.1 KFY02267.1 - 1.6e-43 148.1 4.2 1.9e-43 147.9 4.2 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal protein mL59 zf-CSL PF05207.13 KFY02268.1 - 5.4e-20 70.9 0.5 8e-20 70.3 0.5 1.3 1 0 0 1 1 1 1 CSL zinc finger DnaJ PF00226.31 KFY02268.1 - 1.4e-12 47.6 0.8 5e-12 45.8 0.8 1.8 1 1 0 1 1 1 1 DnaJ domain Mnd1 PF03962.15 KFY02269.1 - 1.4e-22 79.7 0.4 3.9e-22 78.3 0.1 2.0 2 0 0 2 2 2 1 Mnd1 HTH domain P_C10 PF14974.6 KFY02269.1 - 0.049 13.7 0.3 1.7 8.8 0.0 2.8 3 0 0 3 3 3 0 Protein C10 sCache_like PF16736.5 KFY02269.1 - 0.29 11.2 3.4 0.43 10.7 2.5 1.8 1 1 0 1 1 1 0 Single Cache-like CorA PF01544.18 KFY02269.1 - 0.74 9.1 5.7 1 8.6 5.7 1.2 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein Arrestin_N PF00339.29 KFY02270.1 - 2e-17 63.6 0.0 7.8e-17 61.7 0.0 2.0 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.22 KFY02270.1 - 3.4e-11 43.7 0.0 2.6e-08 34.4 0.0 3.0 2 1 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain DLH PF01738.18 KFY02271.1 - 1.6e-33 116.1 0.1 1.8e-33 115.9 0.1 1.0 1 0 0 1 1 1 1 Dienelactone hydrolase family DUF3530 PF12048.8 KFY02271.1 - 0.019 14.4 0.0 0.02 14.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3530) Nas2_N PF18265.1 KFY02272.1 - 3.9e-27 94.0 0.0 5.7e-27 93.5 0.0 1.2 1 0 0 1 1 1 1 Nas2 N_terminal domain PDZ_2 PF13180.6 KFY02272.1 - 1.1e-08 35.2 0.0 1.8e-08 34.6 0.0 1.3 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 KFY02272.1 - 6.6e-08 32.3 0.3 1.2e-07 31.4 0.3 1.5 1 0 0 1 1 1 1 PDZ domain GRASP55_65 PF04495.14 KFY02272.1 - 0.00012 22.4 0.0 0.00024 21.5 0.0 1.4 1 0 0 1 1 1 1 GRASP55/65 PDZ-like domain PDZ PF00595.24 KFY02272.1 - 0.0082 16.5 0.0 0.013 15.8 0.0 1.4 1 0 0 1 1 1 1 PDZ domain PAP2 PF01569.21 KFY02273.1 - 1.3e-12 47.6 0.9 1e-11 44.8 0.9 2.2 1 1 0 1 1 1 1 PAP2 superfamily DUF212 PF02681.14 KFY02273.1 - 0.00023 21.3 0.1 0.015 15.5 0.0 2.2 2 0 0 2 2 2 2 Divergent PAP2 family Ras PF00071.22 KFY02274.1 - 3.8e-49 166.4 0.0 4.5e-49 166.2 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFY02274.1 - 1.4e-29 102.8 0.1 3.5e-29 101.5 0.0 1.6 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFY02274.1 - 2.1e-10 40.3 0.0 2.9e-10 39.9 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family RNA_helicase PF00910.22 KFY02274.1 - 0.00014 22.2 0.1 0.00067 20.0 0.1 2.0 1 1 0 1 1 1 1 RNA helicase MMR_HSR1 PF01926.23 KFY02274.1 - 0.00026 21.0 0.0 0.00046 20.2 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 KFY02274.1 - 0.002 17.5 0.0 0.0025 17.2 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Pox_A32 PF04665.12 KFY02274.1 - 0.023 14.2 0.1 0.044 13.2 0.1 1.4 1 0 0 1 1 1 0 Poxvirus A32 protein RsgA_GTPase PF03193.16 KFY02274.1 - 0.033 14.1 0.1 9 6.2 0.0 2.2 2 0 0 2 2 2 0 RsgA GTPase AAA_7 PF12775.7 KFY02274.1 - 0.036 13.6 0.1 0.062 12.8 0.1 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region G-alpha PF00503.20 KFY02274.1 - 0.051 12.7 2.6 2 7.5 0.2 2.6 2 1 1 3 3 3 0 G-protein alpha subunit AAA_24 PF13479.6 KFY02274.1 - 0.064 13.0 0.1 0.11 12.2 0.1 1.4 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 KFY02274.1 - 0.11 12.9 0.1 0.2 12.0 0.1 1.5 2 0 0 2 2 2 0 AAA ATPase domain TsaE PF02367.17 KFY02274.1 - 0.11 12.5 0.1 0.25 11.3 0.1 1.6 2 0 0 2 2 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_33 PF13671.6 KFY02274.1 - 0.12 12.5 0.2 0.22 11.7 0.2 1.4 1 0 0 1 1 1 0 AAA domain Telomere_reg-2 PF10193.9 KFY02276.1 - 8.2e-36 122.8 0.0 2.1e-35 121.4 0.0 1.8 1 0 0 1 1 1 1 Telomere length regulation protein ThiF PF00899.21 KFY02277.1 - 3.4e-62 210.0 0.0 4.8e-62 209.5 0.0 1.1 1 0 0 1 1 1 1 ThiF family E2_bind PF08825.10 KFY02277.1 - 7.8e-29 99.7 0.0 1.5e-28 98.8 0.0 1.4 1 0 0 1 1 1 1 E2 binding domain Shikimate_DH PF01488.20 KFY02277.1 - 0.0019 18.3 0.7 0.0037 17.3 0.1 1.8 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase UDPG_MGDP_dh_N PF03721.14 KFY02277.1 - 0.033 13.8 0.2 0.056 13.0 0.2 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain PglD_N PF17836.1 KFY02277.1 - 0.056 14.1 0.6 0.21 12.2 0.2 2.2 2 0 0 2 2 2 0 PglD N-terminal domain Ecm33 PF12454.8 KFY02277.1 - 0.083 13.0 0.7 0.21 11.8 0.7 1.6 1 0 0 1 1 1 0 GPI-anchored cell wall organization protein Pyr_redox PF00070.27 KFY02277.1 - 0.11 13.0 0.0 0.22 12.1 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase GARS_N PF02844.15 KFY02277.1 - 0.13 13.1 0.0 0.38 11.6 0.0 1.9 1 0 0 1 1 1 0 Phosphoribosylglycinamide synthetase, N domain CRC_subunit PF08624.10 KFY02277.1 - 0.15 12.5 0.0 0.39 11.2 0.0 1.6 2 0 0 2 2 2 0 Chromatin remodelling complex Rsc7/Swp82 subunit RNA_pol_A_bac PF01000.26 KFY02278.1 - 2.1e-25 89.3 0.0 4.3e-25 88.3 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.24 KFY02278.1 - 8.5e-22 76.4 0.0 1.3e-21 75.8 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Complex1_49kDa PF00346.19 KFY02279.1 - 3e-124 413.5 0.0 4.1e-124 413.0 0.0 1.2 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 49 Kd subunit NiFeSe_Hases PF00374.19 KFY02279.1 - 0.013 14.4 0.0 0.024 13.5 0.0 1.4 1 1 0 1 1 1 0 Nickel-dependent hydrogenase UQ_con PF00179.26 KFY02280.1 - 1.2e-22 80.1 0.2 2.5e-22 79.1 0.0 1.6 2 0 0 2 2 2 1 Ubiquitin-conjugating enzyme UEV PF05743.13 KFY02280.1 - 0.027 14.3 0.0 0.048 13.5 0.0 1.3 1 0 0 1 1 1 0 UEV domain RWD PF05773.22 KFY02280.1 - 0.085 13.1 0.0 0.19 12.0 0.0 1.5 1 0 0 1 1 1 0 RWD domain Pkinase PF00069.25 KFY02281.1 - 2.5e-69 233.6 0.0 3.5e-69 233.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFY02281.1 - 6.8e-37 127.2 0.0 1e-36 126.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KFY02281.1 - 8.8e-09 35.1 0.0 1.3e-08 34.6 0.0 1.3 1 0 0 1 1 1 1 Kinase-like YrbL-PhoP_reg PF10707.9 KFY02281.1 - 0.0035 16.9 0.1 0.27 10.7 0.0 2.5 2 0 0 2 2 2 1 PhoP regulatory network protein YrbL Kdo PF06293.14 KFY02281.1 - 0.0037 16.6 0.0 0.0071 15.7 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family ENTH PF01417.20 KFY02287.1 - 1.3e-49 167.4 0.1 1.8e-49 167.0 0.1 1.2 1 0 0 1 1 1 1 ENTH domain ANTH PF07651.16 KFY02287.1 - 1.4e-05 24.2 0.0 2.1e-05 23.6 0.0 1.2 1 0 0 1 1 1 1 ANTH domain UIM PF02809.20 KFY02287.1 - 0.0006 19.6 7.6 0.013 15.4 0.3 3.3 2 2 0 2 2 2 2 Ubiquitin interaction motif VHS PF00790.19 KFY02287.1 - 0.0013 18.6 0.0 0.0023 17.8 0.0 1.4 1 0 0 1 1 1 1 VHS domain AIM3 PF17096.5 KFY02287.1 - 0.25 12.3 3.8 3.1 8.8 1.8 2.4 2 0 0 2 2 2 0 Altered inheritance of mitochondria protein 3 AAR2 PF05282.11 KFY02287.1 - 0.45 9.9 0.0 0.45 9.9 0.0 2.0 1 1 1 2 2 2 0 AAR2 protein EF-hand_1 PF00036.32 KFY02288.1 - 2.7e-16 57.8 4.0 1.7e-08 33.4 0.2 3.4 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.6 KFY02288.1 - 1.3e-14 52.8 2.8 3.4e-07 29.7 0.3 2.9 2 0 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.6 KFY02288.1 - 1.5e-14 54.2 2.9 1.8e-07 31.5 0.4 2.3 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 KFY02288.1 - 7.8e-12 44.9 6.5 0.0003 20.6 0.2 3.2 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_5 PF13202.6 KFY02288.1 - 1.8e-08 33.5 2.0 0.00021 20.7 0.1 2.8 2 0 0 2 2 2 2 EF hand EF-hand_4 PF12763.7 KFY02288.1 - 0.0004 20.3 0.1 0.0013 18.7 0.0 1.8 2 0 0 2 2 2 1 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.6 KFY02288.1 - 0.0065 16.8 0.0 0.52 10.7 0.0 2.4 2 0 0 2 2 2 1 EF-hand domain Methyltransf_3 PF01596.17 KFY02288.1 - 0.038 13.2 0.1 0.058 12.6 0.1 1.2 1 0 0 1 1 1 0 O-methyltransferase Caleosin PF05042.13 KFY02288.1 - 0.055 13.4 0.0 1 9.3 0.0 2.1 2 0 0 2 2 2 0 Caleosin related protein DUF150 PF02576.17 KFY02288.1 - 0.16 12.4 0.1 0.36 11.3 0.1 1.6 1 0 0 1 1 1 0 RimP N-terminal domain Nup96 PF12110.8 KFY02289.1 - 5.1e-95 317.9 0.8 7e-95 317.5 0.8 1.2 1 0 0 1 1 1 1 Nuclear protein 96 Nucleoporin2 PF04096.14 KFY02289.1 - 5.5e-48 162.9 0.0 9.1e-48 162.2 0.0 1.4 1 0 0 1 1 1 1 Nucleoporin autopeptidase Nucleoporin_FG PF13634.6 KFY02289.1 - 1.9e-12 47.9 114.0 8.5e-08 32.9 36.0 11.4 4 2 6 10 10 10 4 Nucleoporin FG repeat region Spt20 PF12090.8 KFY02289.1 - 8.3 5.9 9.4 24 4.5 9.4 1.7 1 0 0 1 1 1 0 Spt20 family AA_permease_2 PF13520.6 KFY02291.1 - 4.4e-55 187.2 27.7 5.4e-55 186.9 27.7 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KFY02291.1 - 1.3e-22 80.1 23.8 1.9e-22 79.5 23.8 1.2 1 0 0 1 1 1 1 Amino acid permease Glyco_transf_90 PF05686.12 KFY02292.1 - 3.8e-14 52.4 3.0 3.1e-09 36.3 1.3 3.1 2 1 0 2 2 2 2 Glycosyl transferase family 90 DUF5560 PF17715.1 KFY02292.1 - 0.076 12.5 0.9 0.17 11.4 0.9 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5560) CadC_C1 PF18500.1 KFY02292.1 - 0.098 12.8 0.0 0.18 11.9 0.0 1.3 1 0 0 1 1 1 0 CadC C-terminal domain 1 Ribosomal_L7Ae PF01248.26 KFY02293.1 - 8.6e-28 95.9 1.0 1.1e-27 95.5 1.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family PELOTA_1 PF15608.6 KFY02293.1 - 0.079 12.9 0.0 0.14 12.1 0.0 1.3 1 0 0 1 1 1 0 PELOTA RNA binding domain OPT PF03169.15 KFY02294.1 - 4.5e-92 309.7 43.2 5.1e-92 309.5 43.2 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein Nucleos_tra2_N PF01773.20 KFY02294.1 - 6.1 7.5 10.5 0.56 10.8 3.4 3.0 3 0 0 3 3 3 0 Na+ dependent nucleoside transporter N-terminus Beta-lactamase PF00144.24 KFY02296.1 - 1.9e-36 126.0 0.1 3.6e-36 125.1 0.1 1.4 1 0 0 1 1 1 1 Beta-lactamase Glyco_hydro_106 PF17132.4 KFY02296.1 - 1.6e-29 102.8 0.1 2.2e-29 102.3 0.1 1.1 1 0 0 1 1 1 1 alpha-L-rhamnosidase LRR_8 PF13855.6 KFY02297.1 - 5.1e-31 106.2 54.9 6.2e-07 29.1 6.2 9.0 4 2 4 9 9 9 9 Leucine rich repeat LRR_4 PF12799.7 KFY02297.1 - 4.3e-30 103.3 56.6 2e-08 34.4 3.0 10.4 9 3 2 12 12 12 8 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 KFY02297.1 - 9.6e-08 31.6 43.3 0.67 10.7 0.3 13.6 14 3 0 14 14 14 2 Leucine Rich Repeat LRR_9 PF14580.6 KFY02297.1 - 0.0059 16.1 22.5 2.4 7.7 0.3 4.8 2 2 2 5 5 5 3 Leucine-rich repeat LRR_2 PF07723.13 KFY02297.1 - 0.057 14.1 5.8 2.5 8.9 0.5 4.4 4 0 0 4 4 4 0 Leucine Rich Repeat LRR_6 PF13516.6 KFY02297.1 - 0.067 13.3 38.0 4.4 7.6 0.7 10.8 12 0 0 12 12 12 0 Leucine Rich repeat Bacillus_HBL PF05791.11 KFY02298.1 - 0.14 12.0 0.0 0.24 11.2 0.0 1.3 1 0 0 1 1 1 0 Bacillus haemolytic enterotoxin (HBL) HRI1 PF16815.5 KFY02299.1 - 3e-62 210.3 0.2 3.4e-62 210.2 0.2 1.0 1 0 0 1 1 1 1 Protein HRI1 DUF2759 PF10958.8 KFY02300.1 - 0.44 10.3 1.9 20 5.0 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2759) DEAD PF00270.29 KFY02301.1 - 2.1e-40 138.3 0.0 1e-39 136.1 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KFY02301.1 - 1.4e-29 102.6 0.1 3.6e-29 101.3 0.1 1.7 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KFY02301.1 - 0.00012 22.1 0.0 0.00021 21.3 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit SNF2_N PF00176.23 KFY02301.1 - 0.0039 15.9 0.0 0.005 15.6 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain zf-C2H2_6 PF13912.6 KFY02303.1 - 0.087 12.8 0.5 0.46 10.5 0.1 2.4 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2_4 PF13894.6 KFY02303.1 - 0.54 11.2 11.6 2 9.5 0.4 4.5 4 0 0 4 4 4 0 C2H2-type zinc finger RNase_H PF00075.24 KFY02304.1 - 3.3e-24 85.7 0.0 4.4e-24 85.3 0.0 1.1 1 0 0 1 1 1 1 RNase H RVT_3 PF13456.6 KFY02304.1 - 1.9e-06 27.7 0.0 0.036 13.9 0.0 2.2 2 0 0 2 2 2 2 Reverse transcriptase-like HTH_Tnp_Tc5 PF03221.16 KFY02304.1 - 0.086 12.9 0.1 0.18 11.9 0.1 1.6 1 0 0 1 1 1 0 Tc5 transposase DNA-binding domain Zn_clus PF00172.18 KFY02305.1 - 1.5e-07 31.4 13.0 2.5e-07 30.7 13.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF3666 PF12408.8 KFY02305.1 - 0.066 12.4 0.3 0.27 10.5 0.1 2.0 2 0 0 2 2 2 0 Ribose-5-phosphate isomerase RTA1 PF04479.13 KFY02306.1 - 1.2e-40 139.4 8.0 1.9e-40 138.7 8.0 1.3 1 0 0 1 1 1 1 RTA1 like protein Pyr_redox_2 PF07992.14 KFY02307.1 - 7.9e-34 117.2 0.2 1e-33 116.9 0.2 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KFY02307.1 - 6.6e-12 45.3 0.7 9.8e-12 44.7 0.7 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KFY02307.1 - 1.2e-09 38.6 1.0 6e-09 36.4 0.7 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KFY02307.1 - 0.0027 16.9 0.2 0.0045 16.2 0.2 1.4 1 0 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) HI0933_like PF03486.14 KFY02307.1 - 0.013 14.3 2.9 6.3 5.4 0.1 3.4 4 0 0 4 4 4 0 HI0933-like protein NAD_binding_7 PF13241.6 KFY02307.1 - 0.077 13.4 0.7 0.52 10.8 0.5 2.3 2 1 0 2 2 2 0 Putative NAD(P)-binding GIDA PF01134.22 KFY02307.1 - 0.16 11.0 0.1 0.16 11.0 0.1 2.4 2 1 1 3 3 3 0 Glucose inhibited division protein A Trp_halogenase PF04820.14 KFY02307.1 - 0.17 10.7 4.5 1.1 8.0 0.3 2.2 1 1 1 2 2 2 0 Tryptophan halogenase Lycopene_cycl PF05834.12 KFY02307.1 - 0.51 9.3 4.6 11 5.0 0.1 3.0 2 1 1 3 3 3 0 Lycopene cyclase protein DAO PF01266.24 KFY02307.1 - 0.85 9.1 11.7 8.4 5.9 0.4 3.9 3 1 1 4 4 4 0 FAD dependent oxidoreductase MetallophosN PF16371.5 KFY02307.1 - 2 8.7 4.8 0.65 10.3 0.2 2.4 3 0 0 3 3 3 0 N terminal of Calcineurin-like phosphoesterase NDT80_PhoG PF05224.12 KFY02308.1 - 2.4e-42 145.3 0.0 4.7e-42 144.3 0.0 1.5 1 0 0 1 1 1 1 NDT80 / PhoG like DNA-binding family Fungal_trans_2 PF11951.8 KFY02310.1 - 1.4e-59 201.9 1.0 1.7e-59 201.6 1.0 1.0 1 0 0 1 1 1 1 Fungal specific transcription factor domain Alpha-L-AF_C PF06964.12 KFY02311.1 - 1.1e-29 103.8 0.2 1.5e-29 103.3 0.2 1.2 1 0 0 1 1 1 1 Alpha-L-arabinofuranosidase C-terminal domain Glyco_hydro_30C PF17189.4 KFY02311.1 - 0.066 13.4 0.2 0.3 11.3 0.2 2.0 1 1 0 1 1 1 0 Glycosyl hydrolase family 30 beta sandwich domain Acyl_transf_3 PF01757.22 KFY02312.1 - 8.2e-18 64.6 17.3 1.1e-17 64.1 17.3 1.1 1 0 0 1 1 1 1 Acyltransferase family Sugar_tr PF00083.24 KFY02313.1 - 9.3e-102 341.2 22.2 1.2e-101 340.9 22.2 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KFY02313.1 - 4e-26 91.8 38.9 6.3e-19 68.1 14.1 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily DIOX_N PF14226.6 KFY02313.1 - 3.1e-05 24.7 0.0 8e-05 23.4 0.0 1.7 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 KFY02313.1 - 0.0003 21.2 0.0 0.00063 20.2 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily MatC_N PF07158.11 KFY02313.1 - 1.3 9.1 10.1 0.94 9.5 6.0 2.8 3 0 0 3 3 3 0 Dicarboxylate carrier protein MatC N-terminus Flot PF15975.5 KFY02313.1 - 4.2 7.6 5.3 8.8 6.5 5.3 1.5 1 0 0 1 1 1 0 Flotillin RTA1 PF04479.13 KFY02314.1 - 1.7e-73 246.7 5.5 2.7e-73 246.0 5.5 1.3 1 0 0 1 1 1 1 RTA1 like protein ATP1G1_PLM_MAT8 PF02038.16 KFY02314.1 - 0.0012 18.3 0.2 0.0012 18.3 0.2 2.4 2 0 0 2 2 2 1 ATP1G1/PLM/MAT8 family HisKA_4TM PF16926.5 KFY02314.1 - 0.14 11.8 0.1 0.14 11.8 0.1 2.2 3 0 0 3 3 3 0 Archaeal 4TM region of histidine kinase PLDc_2 PF13091.6 KFY02315.1 - 4.2e-16 59.0 0.0 2e-09 37.4 0.0 2.7 2 0 0 2 2 2 2 PLD-like domain PLDc PF00614.22 KFY02315.1 - 0.00022 21.3 0.4 0.3 11.4 0.1 3.5 3 0 0 3 3 3 2 Phospholipase D Active site motif Methyltransf_23 PF13489.6 KFY02316.1 - 8.5e-22 77.7 0.0 1.4e-21 77.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KFY02316.1 - 1.2e-13 51.5 0.0 5.1e-13 49.6 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 KFY02316.1 - 1.4e-10 41.6 0.0 4e-10 40.2 0.0 1.7 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KFY02316.1 - 1.4e-08 35.4 0.0 5e-08 33.6 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KFY02316.1 - 1.5e-08 34.5 0.0 1.4e-06 28.2 0.0 2.9 1 1 1 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 KFY02316.1 - 2.4e-07 30.3 0.0 6.2e-06 25.7 0.0 2.7 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family PrmA PF06325.13 KFY02316.1 - 0.0027 17.2 0.0 0.0046 16.4 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_16 PF10294.9 KFY02316.1 - 0.005 16.6 0.0 0.0085 15.8 0.0 1.3 1 0 0 1 1 1 1 Lysine methyltransferase MTS PF05175.14 KFY02316.1 - 0.008 15.7 0.0 0.025 14.1 0.0 1.8 3 0 0 3 3 3 1 Methyltransferase small domain Methyltransf_4 PF02390.17 KFY02316.1 - 0.0093 15.5 0.0 0.021 14.3 0.0 1.5 1 0 0 1 1 1 1 Putative methyltransferase DUF938 PF06080.12 KFY02316.1 - 0.038 13.7 0.0 0.082 12.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF938) PASTA PF03793.19 KFY02316.1 - 0.085 12.7 0.1 0.82 9.6 0.0 2.6 2 0 0 2 2 2 0 PASTA domain Methyltransf_8 PF05148.15 KFY02316.1 - 0.13 12.0 0.0 0.45 10.3 0.0 2.0 1 1 0 1 1 1 0 Hypothetical methyltransferase Ribosomal_60s PF00428.19 KFY02316.1 - 1.8 9.2 4.6 3.4 8.3 3.9 1.8 2 0 0 2 2 2 0 60s Acidic ribosomal protein Dopey_N PF04118.14 KFY02317.1 - 0.022 13.9 0.6 0.15 11.1 0.0 2.1 1 1 0 2 2 2 0 Dopey, N-terminal T3SS_needle_E PF08988.10 KFY02317.1 - 0.12 12.5 2.6 0.15 12.3 0.3 2.4 2 0 0 2 2 2 0 Type III secretion system, cytoplasmic E component of needle FAA_hydro_N_2 PF18288.1 KFY02317.1 - 0.48 10.9 3.5 6.7 7.2 0.1 3.6 3 1 1 4 4 4 0 Fumarylacetoacetase N-terminal domain 2 Cluap1 PF10234.9 KFY02317.1 - 1.5 8.2 9.3 0.26 10.6 5.5 1.7 2 0 0 2 2 2 0 Clusterin-associated protein-1 IML1 PF12257.8 KFY02318.1 - 3.8e-113 377.4 0.0 5.7e-113 376.8 0.0 1.3 1 0 0 1 1 1 1 Vacuolar membrane-associated protein Iml1 DEP PF00610.21 KFY02318.1 - 2.5e-27 94.7 0.1 5.1e-27 93.7 0.1 1.6 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) Cu_bind_like PF02298.17 KFY02320.1 - 8.1e-05 22.6 0.8 0.00074 19.5 0.3 2.5 1 1 1 2 2 2 1 Plastocyanin-like domain Copper-bind PF00127.20 KFY02320.1 - 0.03 14.8 0.0 0.092 13.2 0.0 1.9 1 1 0 1 1 1 0 Copper binding proteins, plastocyanin/azurin family Acetyltransf_3 PF13302.7 KFY02321.1 - 4.8e-11 43.5 0.0 9.1e-11 42.6 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KFY02321.1 - 4.4e-05 23.7 0.0 6.8e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Na_Ca_ex PF01699.24 KFY02322.1 - 3.9e-44 150.3 41.7 1.6e-23 83.4 17.0 2.2 2 0 0 2 2 2 2 Sodium/calcium exchanger protein DUF4079 PF13301.6 KFY02322.1 - 0.0024 18.0 0.0 0.0024 18.0 0.0 3.0 3 1 0 3 3 3 1 Protein of unknown function (DUF4079) NUC153 PF08159.12 KFY02323.1 - 5.8e-14 51.6 0.1 5.8e-14 51.6 0.1 4.0 5 0 0 5 5 5 3 NUC153 domain RTX PF02382.15 KFY02324.1 - 7 6.2 9.8 10 5.7 9.8 1.1 1 0 0 1 1 1 0 N-terminal domain in RTX protein AMP-binding PF00501.28 KFY02325.1 - 4.8e-164 546.0 0.0 1.5e-87 293.9 0.0 2.2 2 0 0 2 2 2 2 AMP-binding enzyme Condensation PF00668.20 KFY02325.1 - 5.5e-60 203.3 0.0 8.9e-29 100.5 0.1 2.8 3 0 0 3 3 3 2 Condensation domain PP-binding PF00550.25 KFY02325.1 - 6.2e-18 64.9 1.1 8.2e-08 32.5 0.0 3.3 3 0 0 3 3 3 2 Phosphopantetheine attachment site AMP-binding_C PF13193.6 KFY02325.1 - 8.9e-09 36.2 0.0 2.3e-06 28.5 0.0 2.9 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain ADH_zinc_N PF00107.26 KFY02326.1 - 3.2e-07 30.4 0.1 5e-07 29.7 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KFY02326.1 - 2.3e-05 24.2 0.0 6.3e-05 22.8 0.0 1.7 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_N_2 PF16884.5 KFY02326.1 - 0.024 14.5 0.0 0.075 12.9 0.0 1.8 1 1 0 1 1 1 0 N-terminal domain of oxidoreductase CMD PF02627.20 KFY02327.1 - 0.11 12.5 0.0 0.66 10.1 0.0 2.2 2 1 1 3 3 3 0 Carboxymuconolactone decarboxylase family p450 PF00067.22 KFY02328.1 - 6.7e-67 226.2 0.0 8.8e-67 225.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 MFS_1 PF07690.16 KFY02329.1 - 3.9e-32 111.5 61.2 4.8e-30 104.7 39.4 3.3 2 1 1 3 3 3 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KFY02329.1 - 4.1e-11 42.4 8.8 4.1e-11 42.4 8.8 2.6 3 0 0 3 3 3 1 Sugar (and other) transporter OATP PF03137.20 KFY02329.1 - 0.051 11.9 13.1 0.26 9.5 2.6 2.5 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family Fungal_trans PF04082.18 KFY02330.1 - 1.1e-12 47.5 3.7 1.9e-11 43.5 3.7 2.3 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KFY02330.1 - 1.4e-06 28.3 9.9 1.4e-06 28.3 9.9 2.2 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-H2C2_2 PF13465.6 KFY02330.1 - 0.00026 21.3 21.6 0.051 14.0 7.4 3.8 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2 PF00096.26 KFY02330.1 - 0.00032 21.0 22.2 0.0058 17.0 4.7 3.1 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2HE PF16278.5 KFY02330.1 - 0.56 10.7 8.4 3.3 8.2 0.7 2.6 1 1 1 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger Cytochrome_C7 PF14522.6 KFY02330.1 - 2.2 8.3 16.7 0.29 11.2 6.7 2.4 1 1 1 2 2 2 0 Cytochrome c7 and related cytochrome c zf-C2H2_jaz PF12171.8 KFY02330.1 - 2.4 8.6 7.7 5.1 7.5 1.2 2.7 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.6 KFY02330.1 - 3.1 8.9 23.8 0.11 13.4 3.1 3.2 3 0 0 3 3 3 0 C2H2-type zinc finger zf_C2H2_ZHX PF18387.1 KFY02330.1 - 8.9 6.0 6.1 14 5.4 4.7 2.1 1 1 0 1 1 1 0 Zinc-fingers and homeoboxes C2H2 finger domain Glyco_hydro_127 PF07944.12 KFY02331.1 - 1.9e-116 389.6 0.0 2.3e-116 389.3 0.0 1.0 1 0 0 1 1 1 1 Beta-L-arabinofuranosidase, GH127 Sugar_tr PF00083.24 KFY02332.1 - 1e-67 229.0 21.4 1.3e-67 228.7 21.4 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KFY02332.1 - 8.5e-16 57.8 28.2 5.8e-13 48.5 26.6 2.5 1 1 2 3 3 3 2 Major Facilitator Superfamily DDE_Tnp_IS1 PF03400.13 KFY02334.1 - 0.036 14.4 0.1 0.075 13.4 0.1 1.5 1 0 0 1 1 1 0 IS1 transposase PPK2 PF03976.14 KFY02334.1 - 0.091 12.3 0.0 7.5 6.0 0.0 2.4 2 0 0 2 2 2 0 Polyphosphate kinase 2 (PPK2) DUF3834 PF12916.7 KFY02334.1 - 0.2 10.9 0.0 0.32 10.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3834) MFS_1 PF07690.16 KFY02335.1 - 2.6e-12 46.3 18.7 2.6e-12 46.3 18.7 1.9 2 1 0 2 2 2 1 Major Facilitator Superfamily Aa_trans PF01490.18 KFY02336.1 - 4.1e-81 272.8 25.3 4.8e-81 272.5 25.3 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Fig1 PF12351.8 KFY02336.1 - 0.047 13.6 5.9 0.65 9.9 1.1 2.4 2 0 0 2 2 2 0 Ca2+ regulator and membrane fusion protein Fig1 OST3_OST6 PF04756.13 KFY02336.1 - 4.3 6.6 6.4 0.77 9.0 0.5 2.3 2 1 1 3 3 3 0 OST3 / OST6 family, transporter family Aldedh PF00171.22 KFY02337.1 - 9.2e-135 449.7 0.1 1.1e-134 449.5 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.14 KFY02337.1 - 0.011 14.8 0.0 0.027 13.5 0.0 1.7 1 1 0 1 1 1 0 Acyl-CoA reductase (LuxC) DUF3201 PF11447.8 KFY02337.1 - 0.11 12.0 0.1 0.35 10.4 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3201) HMG_box PF00505.19 KFY02343.1 - 1.6e-10 41.2 0.2 1.6e-10 41.2 0.2 2.1 3 0 0 3 3 3 1 HMG (high mobility group) box SAM_1 PF00536.30 KFY02343.1 - 1.8e-10 41.1 0.1 3.6e-10 40.1 0.1 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) HMG_box_2 PF09011.10 KFY02343.1 - 1.4e-09 38.4 0.3 3.3e-09 37.2 0.3 1.6 1 0 0 1 1 1 1 HMG-box domain SAM_2 PF07647.17 KFY02343.1 - 2e-05 24.6 0.1 4.7e-05 23.4 0.1 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) LRR_6 PF13516.6 KFY02366.1 - 2.5e-12 45.8 19.9 4.3 7.6 0.1 11.8 13 0 0 13 13 13 6 Leucine Rich repeat LRR_4 PF12799.7 KFY02366.1 - 8.6e-12 45.1 15.1 0.25 11.8 0.4 7.1 6 1 1 7 7 7 6 Leucine Rich repeats (2 copies) F-box-like PF12937.7 KFY02366.1 - 1e-10 41.3 0.4 7.1e-10 38.6 0.4 2.5 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 KFY02366.1 - 4e-06 26.6 0.0 0.00012 21.9 0.0 2.9 2 0 0 2 2 2 1 F-box domain DUF1699 PF08004.11 KFY02366.1 - 0.0033 17.1 1.8 1.7 8.3 0.0 3.7 3 1 0 3 3 3 1 Protein of unknown function (DUF1699) AMP-binding PF00501.28 KFY02367.1 - 1.7e-73 247.6 0.1 2.1e-73 247.3 0.1 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KFY02367.1 - 1.8e-19 70.5 0.1 3.7e-19 69.5 0.1 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain LysR_substrate PF03466.20 KFY02367.1 - 0.06 12.7 0.0 0.12 11.7 0.0 1.5 1 0 0 1 1 1 0 LysR substrate binding domain Ribosomal_L13 PF00572.18 KFY02368.1 - 2.3e-10 40.8 0.0 2e-08 34.5 0.0 2.3 1 1 0 1 1 1 1 Ribosomal protein L13 Glutaredoxin PF00462.24 KFY02369.1 - 5.7e-19 68.1 0.0 9.1e-19 67.4 0.0 1.3 1 0 0 1 1 1 1 Glutaredoxin Thioredoxin_2 PF13098.6 KFY02369.1 - 0.001 19.5 0.1 0.0026 18.2 0.1 1.6 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_3 PF13192.6 KFY02369.1 - 0.0046 17.0 0.0 0.0069 16.4 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin domain Thioredoxin PF00085.20 KFY02369.1 - 0.0049 16.8 0.1 0.0058 16.6 0.1 1.1 1 0 0 1 1 1 1 Thioredoxin DUF836 PF05768.14 KFY02369.1 - 0.005 17.2 0.0 0.0065 16.9 0.0 1.3 1 1 0 1 1 1 1 Glutaredoxin-like domain (DUF836) DSBA PF01323.20 KFY02369.1 - 0.028 14.2 0.3 0.97 9.2 0.1 2.1 1 1 1 2 2 2 0 DSBA-like thioredoxin domain Thioredoxin_4 PF13462.6 KFY02369.1 - 0.11 12.7 1.7 4.2 7.5 0.0 2.1 1 1 1 2 2 2 0 Thioredoxin GST_N_2 PF13409.6 KFY02369.1 - 0.14 12.5 0.0 0.18 12.2 0.0 1.2 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain Chalcone_2 PF16035.5 KFY02370.1 - 3e-76 255.8 0.0 3.8e-76 255.4 0.0 1.1 1 0 0 1 1 1 1 Chalcone isomerase like Chalcone_3 PF16036.5 KFY02370.1 - 0.00043 20.4 0.0 0.06 13.5 0.0 2.3 2 0 0 2 2 2 2 Chalcone isomerase-like Chalcone PF02431.15 KFY02370.1 - 0.019 14.4 0.0 0.095 12.1 0.0 1.9 2 0 0 2 2 2 0 Chalcone-flavanone isomerase Rrn6 PF10214.9 KFY02371.1 - 3.3e-202 674.3 0.0 4e-202 674.1 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase I-specific transcription-initiation factor adh_short PF00106.25 KFY02372.1 - 1.8e-08 34.1 0.0 3.2e-08 33.3 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KFY02372.1 - 1.1e-06 28.7 0.1 1.8e-06 28.0 0.1 1.3 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.6 KFY02372.1 - 4.9e-05 23.0 0.0 9e-05 22.1 0.0 1.4 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase PD40 PF07676.12 KFY02373.1 - 1.7e-50 168.0 27.8 3.8e-08 33.1 0.2 9.8 9 0 0 9 9 9 9 WD40-like Beta Propeller Repeat DPPIV_N PF00930.21 KFY02373.1 - 2.9e-11 42.8 10.0 0.19 10.4 0.0 7.0 3 2 2 6 6 6 5 Dipeptidyl peptidase IV (DPP IV) N-terminal region DUF3748 PF12566.8 KFY02373.1 - 0.00082 19.3 2.5 15 5.5 0.0 5.0 6 0 0 6 6 6 1 Protein of unknown function (DUF3748) TruB_C PF09142.11 KFY02373.1 - 0.0033 17.2 0.0 4.5 7.1 0.0 4.8 5 0 0 5 5 5 1 tRNA Pseudouridine synthase II, C terminal DUF1513 PF07433.11 KFY02373.1 - 0.012 14.7 0.1 0.077 12.1 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1513) Bac_rhamnosid_N PF08531.10 KFY02373.1 - 0.017 15.0 0.1 0.041 13.7 0.1 1.6 1 0 0 1 1 1 0 Alpha-L-rhamnosidase N-terminal domain Pectate_lyase22 PF14583.6 KFY02373.1 - 0.069 11.8 0.2 2.7 6.6 0.0 3.5 3 1 0 3 3 3 0 Oligogalacturonate lyase adh_short PF00106.25 KFY02374.1 - 1.9e-12 47.1 0.0 2.9e-12 46.5 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase Sacchrp_dh_NADP PF03435.18 KFY02374.1 - 0.00086 19.6 0.0 0.0013 18.9 0.0 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Shikimate_DH PF01488.20 KFY02374.1 - 0.00087 19.4 0.0 0.0014 18.7 0.0 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase TrkA_N PF02254.18 KFY02374.1 - 0.0063 16.8 0.0 0.011 16.0 0.0 1.3 1 0 0 1 1 1 1 TrkA-N domain KR PF08659.10 KFY02374.1 - 0.046 13.6 0.0 0.069 13.0 0.0 1.2 1 0 0 1 1 1 0 KR domain Nitroreductase PF00881.24 KFY02374.1 - 0.12 12.4 0.0 0.18 11.9 0.0 1.2 1 0 0 1 1 1 0 Nitroreductase family COesterase PF00135.28 KFY02375.1 - 5.2e-82 276.4 0.0 7e-82 275.9 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KFY02375.1 - 1.6e-06 28.1 0.0 1.7e-05 24.8 0.0 2.3 2 1 0 2 2 2 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KFY02375.1 - 0.00092 18.7 1.4 0.00096 18.7 0.3 1.5 2 0 0 2 2 2 1 Prolyl oligopeptidase family FMN_dh PF01070.18 KFY02377.1 - 2.1e-117 392.0 0.0 2.4e-117 391.8 0.0 1.0 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Glu_synthase PF01645.17 KFY02377.1 - 1.4e-06 27.7 0.0 2.9e-06 26.7 0.0 1.4 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.25 KFY02377.1 - 1.5e-05 24.1 0.6 0.00014 21.0 0.2 2.4 2 1 1 3 3 3 1 IMP dehydrogenase / GMP reductase domain NMO PF03060.15 KFY02377.1 - 5.8e-05 22.6 0.0 9e-05 22.0 0.0 1.3 1 0 0 1 1 1 1 Nitronate monooxygenase ThiG PF05690.14 KFY02377.1 - 0.0001 21.7 0.0 0.043 13.1 0.0 2.3 2 0 0 2 2 2 2 Thiazole biosynthesis protein ThiG DHO_dh PF01180.21 KFY02377.1 - 0.046 12.9 0.2 3.1 6.9 0.0 2.2 2 0 0 2 2 2 0 Dihydroorotate dehydrogenase Dus PF01207.17 KFY02377.1 - 0.063 12.4 0.0 2.6 7.0 0.0 2.4 3 0 0 3 3 3 0 Dihydrouridine synthase (Dus) His_biosynth PF00977.21 KFY02377.1 - 0.085 12.3 0.1 0.48 9.8 0.0 2.1 2 0 0 2 2 2 0 Histidine biosynthesis protein Helicase_C PF00271.31 KFY02383.1 - 5.3e-19 68.6 0.0 1.1e-18 67.6 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Bromodomain PF00439.25 KFY02383.1 - 1.2e-18 66.9 0.2 3.1e-18 65.6 0.2 1.7 1 0 0 1 1 1 1 Bromodomain SnAC PF14619.6 KFY02383.1 - 1.6e-13 51.0 0.4 1.6e-13 51.0 0.4 2.2 2 0 0 2 2 2 1 Snf2-ATP coupling, chromatin remodelling complex HDA2-3 PF11496.8 KFY02383.1 - 2.4e-05 23.6 0.0 7.8e-05 22.0 0.0 1.7 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 Trypan_PARP PF05887.11 KFY02383.1 - 0.33 10.9 10.2 0.82 9.7 10.2 1.6 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) PQ-loop PF04193.14 KFY02385.1 - 3.4e-21 74.8 18.5 2.4e-11 43.2 1.8 3.4 3 1 1 4 4 4 2 PQ loop repeat ER_lumen_recept PF00810.18 KFY02385.1 - 0.013 16.3 1.3 0.049 14.5 0.4 2.1 1 1 1 2 2 2 0 ER lumen protein retaining receptor Adipogenin PF15202.6 KFY02385.1 - 0.23 11.5 4.7 6.6 6.8 0.6 2.6 2 0 0 2 2 2 0 Adipogenin DUF2975 PF11188.8 KFY02385.1 - 5.9 6.8 9.5 0.39 10.6 2.1 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF2975) WD40 PF00400.32 KFY02386.1 - 2.8e-05 24.8 10.0 0.085 13.8 0.0 6.0 7 0 0 7 7 7 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFY02386.1 - 0.0072 16.6 0.0 0.65 10.3 0.0 3.2 3 0 0 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain Astro_capsid_p PF12226.8 KFY02386.1 - 8.1 5.5 7.0 11 5.0 7.0 1.2 1 0 0 1 1 1 0 Turkey astrovirus capsid protein Nucleoporin_FG PF13634.6 KFY02387.1 - 4.3e-18 65.9 78.7 5.3e-10 40.0 36.4 3.6 1 1 2 3 3 3 3 Nucleoporin FG repeat region AAA_lid_9 PF17871.1 KFY02393.1 - 0.0019 18.1 0.3 0.53 10.2 0.0 3.6 4 0 0 4 4 4 1 AAA lid domain Fibrinogen_aC PF12160.8 KFY02393.1 - 0.27 11.1 5.3 6.4 6.7 0.0 3.3 4 0 0 4 4 4 0 Fibrinogen alpha C domain Peptidase_C48 PF02902.19 KFY02404.1 - 2.6e-05 24.2 0.0 4.7e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain USP19_linker PF16602.5 KFY02404.1 - 0.095 13.3 1.0 0.33 11.5 1.0 1.9 1 0 0 1 1 1 0 Linker region of USP19 deubiquitinase GCV_H PF01597.19 KFY02405.1 - 0.15 12.0 0.0 0.3 11.0 0.0 1.5 1 0 0 1 1 1 0 Glycine cleavage H-protein bZIP_1 PF00170.21 KFY02407.1 - 0.0085 16.2 0.5 0.017 15.2 0.5 1.6 1 0 0 1 1 1 1 bZIP transcription factor Peptidase_M13_N PF05649.13 KFY02407.1 - 0.067 12.9 0.1 0.081 12.6 0.1 1.1 1 0 0 1 1 1 0 Peptidase family M13 Ferric_reduct PF01794.19 KFY02408.1 - 3.9e-11 43.1 9.9 3.9e-11 43.1 9.9 2.7 3 1 0 3 3 3 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 KFY02408.1 - 4.6e-07 30.1 0.0 7.4e-07 29.4 0.0 1.3 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 KFY02408.1 - 1e-06 28.8 0.0 2.7e-06 27.4 0.0 1.7 1 0 0 1 1 1 1 FAD-binding domain DUF4112 PF13430.6 KFY02408.1 - 0.079 13.2 1.3 8.7 6.7 0.1 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4112) SRF-TF PF00319.18 KFY02409.1 - 5.5e-07 29.0 0.1 8.8e-07 28.3 0.1 1.4 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) Rx_N PF18052.1 KFY02411.1 - 0.016 15.4 0.2 0.078 13.3 0.4 2.0 2 0 0 2 2 2 0 Rx N-terminal domain Laminin_II PF06009.12 KFY02411.1 - 0.046 13.8 0.4 0.093 12.7 0.4 1.5 1 0 0 1 1 1 0 Laminin Domain II Phosphatase PF15698.5 KFY02414.1 - 0.14 11.3 0.0 0.22 10.6 0.0 1.3 1 1 0 1 1 1 0 Phosphatase Thioredoxin PF00085.20 KFY02429.1 - 8.8e-40 134.9 0.2 7.4e-24 83.7 0.0 4.3 3 1 0 3 3 3 2 Thioredoxin Thioredoxin_6 PF13848.6 KFY02429.1 - 2.2e-11 44.0 0.0 1e-06 28.8 0.0 4.1 3 1 2 5 5 5 2 Thioredoxin-like domain Thioredoxin_8 PF13905.6 KFY02429.1 - 2.8e-05 24.4 0.1 0.65 10.4 0.0 3.9 3 1 1 4 4 4 2 Thioredoxin-like Thioredoxin_3 PF13192.6 KFY02429.1 - 0.00024 21.1 0.0 0.18 11.9 0.0 3.2 3 0 0 3 3 3 1 Thioredoxin domain Thioredoxin_2 PF13098.6 KFY02429.1 - 0.0015 18.9 5.1 1.8 9.0 0.2 4.7 3 2 0 3 3 3 1 Thioredoxin-like domain TraF PF13728.6 KFY02429.1 - 0.011 15.5 3.3 4.6 7.0 0.0 3.2 2 1 1 3 3 3 0 F plasmid transfer operon protein OST3_OST6 PF04756.13 KFY02429.1 - 0.031 13.6 0.0 18 4.6 0.0 3.2 3 0 0 3 3 3 0 OST3 / OST6 family, transporter family DUF3188 PF11384.8 KFY02429.1 - 0.44 10.3 1.5 0.95 9.2 1.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3188) DEC-1_N PF04625.13 KFY02429.1 - 0.5 9.3 4.0 0.89 8.5 4.0 1.3 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region Hydrolase PF00702.26 KFY02431.1 - 0.00029 21.2 0.0 0.0026 18.1 0.0 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Ribosomal_L20 PF00453.18 KFY02431.1 - 0.12 12.5 0.0 0.21 11.7 0.0 1.4 1 0 0 1 1 1 0 Ribosomal protein L20 bZIP_2 PF07716.15 KFY02432.1 - 1.3e-05 25.1 4.0 2.3e-05 24.4 4.0 1.4 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.17 KFY02432.1 - 0.00045 20.7 5.1 0.001 19.5 5.1 1.5 1 0 0 1 1 1 1 bZIP Maf transcription factor bZIP_1 PF00170.21 KFY02432.1 - 0.0058 16.7 6.1 0.013 15.6 5.8 1.7 1 1 0 1 1 1 1 bZIP transcription factor ATG16 PF08614.11 KFY02432.1 - 0.037 14.2 4.5 0.051 13.8 4.5 1.2 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) TolA_bind_tri PF16331.5 KFY02432.1 - 2.1 8.5 7.2 4 7.6 1.6 2.4 2 0 0 2 2 2 0 TolA binding protein trimerisation DUF1635 PF07795.11 KFY02432.1 - 4 7.2 10.0 0.12 12.2 1.4 2.2 1 1 0 2 2 2 0 Protein of unknown function (DUF1635) TPR_10 PF13374.6 KFY02433.1 - 2.7e-24 84.3 7.0 7.2e-08 32.1 0.1 5.7 6 0 0 6 6 5 4 Tetratricopeptide repeat TPR_12 PF13424.6 KFY02433.1 - 2.4e-20 72.6 8.3 7e-11 42.3 0.9 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.17 KFY02433.1 - 1.3e-11 43.7 7.5 0.007 16.4 0.0 4.8 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_8 PF13181.6 KFY02433.1 - 2.6e-11 42.8 3.5 0.0027 17.8 0.0 4.7 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_20 PF14561.6 KFY02433.1 - 9.9e-11 41.8 6.2 0.058 13.7 0.3 5.6 4 1 0 5 5 5 3 Tetratricopeptide repeat TPR_7 PF13176.6 KFY02433.1 - 5e-10 38.7 2.3 0.092 12.8 0.0 5.4 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_6 PF13174.6 KFY02433.1 - 1.7e-09 37.7 5.7 0.11 13.2 0.0 4.6 4 0 0 4 4 3 3 Tetratricopeptide repeat TPR_14 PF13428.6 KFY02433.1 - 5.9e-09 36.0 8.9 0.035 14.9 0.0 5.4 6 0 0 6 6 4 2 Tetratricopeptide repeat ANAPC3 PF12895.7 KFY02433.1 - 2.5e-08 34.0 5.1 0.35 11.1 0.0 5.0 2 1 3 5 5 4 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.6 KFY02433.1 - 5.8e-08 33.1 12.7 0.013 16.0 1.3 5.2 4 1 1 5 5 4 3 Tetratricopeptide repeat UPF0052 PF01933.18 KFY02433.1 - 5.4e-07 29.1 0.6 0.23 10.7 0.0 4.7 2 1 2 4 4 4 1 Uncharacterised protein family UPF0052 PPR PF01535.20 KFY02433.1 - 2.1e-06 27.6 0.4 4 7.9 0.0 4.9 5 0 0 5 5 4 1 PPR repeat TPR_1 PF00515.28 KFY02433.1 - 1e-05 25.1 4.8 1.4 8.9 0.1 4.2 4 0 0 4 4 4 2 Tetratricopeptide repeat NB-ARC PF00931.22 KFY02433.1 - 2.8e-05 23.4 0.0 5.5e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 NB-ARC domain AAA_16 PF13191.6 KFY02433.1 - 3.4e-05 24.3 0.1 0.0004 20.8 0.0 2.6 1 1 1 2 2 2 1 AAA ATPase domain TPR_16 PF13432.6 KFY02433.1 - 3.7e-05 24.3 4.4 0.022 15.4 0.4 3.8 3 1 0 3 3 2 1 Tetratricopeptide repeat Abhydrolase_6 PF12697.7 KFY02433.1 - 7.7e-05 23.4 0.0 0.00019 22.1 0.0 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family TPR_4 PF07721.14 KFY02433.1 - 0.00012 22.3 6.1 0.13 13.0 0.2 3.9 4 0 0 4 4 2 2 Tetratricopeptide repeat PGAP1 PF07819.13 KFY02433.1 - 0.00023 21.0 0.0 0.00049 19.9 0.0 1.5 1 0 0 1 1 1 1 PGAP1-like protein CbiA PF01656.23 KFY02433.1 - 0.00026 21.1 0.0 0.00055 20.0 0.0 2.0 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain TPR_11 PF13414.6 KFY02433.1 - 0.00035 20.2 6.3 1 9.1 0.1 4.1 3 0 0 3 3 3 1 TPR repeat Hydrolase_4 PF12146.8 KFY02433.1 - 0.0013 18.1 0.0 0.0027 17.0 0.0 1.5 1 0 0 1 1 1 1 Serine aminopeptidase, S33 LIDHydrolase PF10230.9 KFY02433.1 - 0.0015 18.1 0.4 0.36 10.3 0.0 3.0 2 1 1 3 3 3 1 Lipid-droplet associated hydrolase Abhydrolase_9 PF10081.9 KFY02433.1 - 0.0021 17.2 0.0 0.0063 15.6 0.0 1.7 2 0 0 2 2 2 1 Alpha/beta-hydrolase family DUF726 PF05277.12 KFY02433.1 - 0.0028 16.6 0.1 0.025 13.5 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF726) AAA_22 PF13401.6 KFY02433.1 - 0.0033 17.7 0.0 0.015 15.6 0.0 2.1 1 0 0 1 1 1 1 AAA domain LCAT PF02450.15 KFY02433.1 - 0.0041 16.4 0.0 0.0091 15.2 0.0 1.5 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase CheW PF01584.19 KFY02433.1 - 0.0096 15.6 0.6 22 4.7 0.0 4.2 1 1 3 4 4 4 0 CheW-like domain YfdX PF10938.8 KFY02433.1 - 0.0097 15.8 2.2 0.22 11.5 0.9 3.2 3 0 0 3 3 3 1 YfdX protein TPR_17 PF13431.6 KFY02433.1 - 0.024 15.0 1.2 13 6.5 0.0 4.0 3 0 0 3 3 3 0 Tetratricopeptide repeat AAA_14 PF13173.6 KFY02433.1 - 0.024 14.7 0.0 0.17 11.9 0.0 2.4 3 0 0 3 3 2 0 AAA domain PPR_2 PF13041.6 KFY02433.1 - 0.03 14.5 0.2 47 4.3 0.0 3.7 3 0 0 3 3 3 0 PPR repeat family DUF676 PF05057.14 KFY02433.1 - 0.033 13.7 0.0 0.11 12.0 0.0 1.8 1 1 0 1 1 1 0 Putative serine esterase (DUF676) ATPase_2 PF01637.18 KFY02433.1 - 0.04 13.8 0.0 0.084 12.8 0.0 1.5 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea ParA PF10609.9 KFY02433.1 - 0.072 12.5 0.0 0.16 11.4 0.0 1.5 1 0 0 1 1 1 0 NUBPL iron-transfer P-loop NTPase DUF3089 PF11288.8 KFY02433.1 - 0.081 12.5 0.0 0.18 11.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3089) DUF4248 PF14053.6 KFY02433.1 - 0.098 12.7 0.0 41 4.3 0.0 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4248) SRP54 PF00448.22 KFY02433.1 - 0.12 12.0 0.0 0.25 11.0 0.0 1.5 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain Alkyl_sulf_dimr PF14863.6 KFY02433.1 - 0.14 12.6 5.1 40 4.6 0.2 4.6 4 1 2 6 6 4 0 Alkyl sulfatase dimerisation DUF627 PF04781.12 KFY02433.1 - 0.15 12.1 0.2 36 4.4 0.0 3.8 4 0 0 4 4 4 0 Protein of unknown function (DUF627) PPR_1 PF12854.7 KFY02433.1 - 0.45 10.3 3.1 30 4.4 0.1 3.5 3 0 0 3 3 3 0 PPR repeat Fis1_TPR_N PF14852.6 KFY02433.1 - 2.5 7.9 4.4 12 5.7 0.2 3.1 3 0 0 3 3 2 0 Fis1 N-terminal tetratricopeptide repeat Gly_transf_sug PF04488.15 KFY02434.1 - 3.4e-09 37.2 0.0 7.4e-09 36.1 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif TcdA_TcdB PF12919.7 KFY02434.1 - 0.013 14.8 0.3 0.02 14.2 0.3 1.1 1 0 0 1 1 1 0 TcdA/TcdB catalytic glycosyltransferase domain DUF3149 PF11346.8 KFY02435.1 - 0.55 9.9 1.5 0.77 9.4 1.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3149) Fungal_trans PF04082.18 KFY02436.1 - 1.2e-12 47.4 0.0 2e-12 46.7 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KFY02436.1 - 2.2e-06 27.7 9.7 4e-06 26.9 9.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain YhhN PF07947.14 KFY02438.1 - 5e-39 133.8 4.2 5e-39 133.8 4.2 2.0 2 1 0 2 2 2 1 YhhN family Esterase_phd PF10503.9 KFY02438.1 - 1.2e-19 70.7 0.1 2e-19 70.0 0.1 1.2 1 0 0 1 1 1 1 Esterase PHB depolymerase Peptidase_S9 PF00326.21 KFY02438.1 - 3.7e-08 33.1 0.5 5.9e-08 32.4 0.5 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family UCR_Fe-S_N PF10399.9 KFY02438.1 - 2.4 7.5 6.7 0.14 11.5 0.7 2.2 2 0 0 2 2 2 0 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal DHquinase_I PF01487.15 KFY02439.1 - 5.6e-28 98.8 0.0 8.2e-28 98.2 0.0 1.3 1 0 0 1 1 1 1 Type I 3-dehydroquinase SKI PF01202.22 KFY02439.1 - 6e-17 62.2 0.3 3e-16 60.0 0.1 2.1 2 0 0 2 2 2 1 Shikimate kinase Shikimate_dh_N PF08501.11 KFY02439.1 - 4.2e-16 59.0 0.0 1.1e-15 57.6 0.0 1.8 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain SDH_C PF18317.1 KFY02439.1 - 4.4e-08 32.7 1.6 1e-07 31.6 1.6 1.7 1 0 0 1 1 1 1 Shikimate 5'-dehydrogenase C-terminal domain Shikimate_DH PF01488.20 KFY02439.1 - 2.3e-06 27.7 0.0 4.8e-06 26.7 0.0 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase AAA_33 PF13671.6 KFY02439.1 - 0.0024 18.0 0.0 0.48 10.6 0.0 2.6 2 0 0 2 2 2 1 AAA domain Fungal_trans PF04082.18 KFY02440.1 - 1.3e-16 60.5 0.1 2.2e-16 59.7 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KFY02440.1 - 5.3e-07 29.7 13.6 8.8e-07 28.9 13.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Inositol_P PF00459.25 KFY02441.1 - 9.3e-74 248.3 0.0 1.1e-73 248.2 0.0 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family Shikimate_dh_N PF08501.11 KFY02442.1 - 1.3e-21 76.7 0.0 2.2e-21 75.9 0.0 1.4 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain SDH_C PF18317.1 KFY02442.1 - 5.2e-06 26.1 0.1 1.7e-05 24.5 0.2 1.8 2 0 0 2 2 2 1 Shikimate 5'-dehydrogenase C-terminal domain Shikimate_DH PF01488.20 KFY02442.1 - 0.016 15.2 0.0 0.024 14.7 0.0 1.2 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Sugar_tr PF00083.24 KFY02443.1 - 1.4e-132 442.7 21.1 1.6e-132 442.6 21.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KFY02443.1 - 3.2e-20 72.4 39.0 1.7e-18 66.7 37.9 2.2 1 1 0 1 1 1 1 Major Facilitator Superfamily AP_endonuc_2 PF01261.24 KFY02444.1 - 5.9e-34 117.4 0.1 1.2e-33 116.3 0.1 1.5 2 0 0 2 2 2 1 Xylose isomerase-like TIM barrel CHAP PF05257.16 KFY02446.1 - 1.3e-13 51.3 1.6 2.4e-13 50.4 1.6 1.5 1 0 0 1 1 1 1 CHAP domain SH3_3 PF08239.11 KFY02446.1 - 1.5e-06 28.4 0.1 5.1e-06 26.7 0.0 2.0 2 0 0 2 2 2 1 Bacterial SH3 domain Cellulase PF00150.18 KFY02447.1 - 2.2e-30 106.0 0.4 4.3e-30 105.1 0.4 1.4 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_20 PF00728.22 KFY02448.1 - 2.4e-28 99.6 0.0 6.5e-26 91.6 0.0 2.4 1 1 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Glyco_hydro_20b PF02838.15 KFY02448.1 - 2.4e-10 41.2 0.0 4.8e-10 40.3 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, domain 2 Collagen PF01391.18 KFY02450.1 - 0.079 12.7 13.3 0.19 11.5 13.3 1.6 1 0 0 1 1 1 0 Collagen triple helix repeat (20 copies) CAP_N PF01213.19 KFY02451.1 - 2.1 7.7 4.7 3.5 7.0 4.7 1.2 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Sugar_tr PF00083.24 KFY02454.1 - 4.1e-67 227.0 23.7 3.8e-48 164.5 3.4 2.0 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 KFY02454.1 - 4.6e-19 68.6 25.1 2e-11 43.4 10.0 2.4 2 1 0 2 2 2 2 Major Facilitator Superfamily MFS_1 PF07690.16 KFY02455.1 - 1.8e-35 122.5 48.5 2.1e-35 122.3 45.9 2.3 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 KFY02455.1 - 1.3e-09 37.0 24.3 1.3e-09 37.0 24.3 1.4 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) GYF PF02213.16 KFY02456.1 - 6.8e-10 38.5 0.9 1.5e-09 37.3 0.9 1.6 1 0 0 1 1 1 1 GYF domain UFD1 PF03152.14 KFY02457.1 - 1.7e-73 245.8 0.0 2.1e-73 245.4 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin fusion degradation protein UFD1 Pyridox_ox_2 PF12900.7 KFY02468.1 - 0.041 13.9 0.0 0.063 13.3 0.0 1.3 1 0 0 1 1 1 0 Pyridoxamine 5'-phosphate oxidase MIT PF04212.18 KFY02469.1 - 0.024 14.7 0.5 0.041 14.0 0.5 1.4 1 0 0 1 1 1 0 MIT (microtubule interacting and transport) domain PRK PF00485.18 KFY02470.1 - 7.3e-06 25.9 0.0 1e-05 25.4 0.0 1.2 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family AAA_18 PF13238.6 KFY02470.1 - 1.4e-05 25.6 0.0 3.1e-05 24.5 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KFY02470.1 - 0.00016 22.1 0.0 0.00023 21.6 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain NB-ARC PF00931.22 KFY02470.1 - 0.00037 19.8 0.0 0.00087 18.5 0.0 1.6 2 0 0 2 2 2 1 NB-ARC domain AAA_17 PF13207.6 KFY02470.1 - 0.00085 19.8 0.1 0.092 13.2 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 KFY02470.1 - 0.002 18.4 0.0 0.0032 17.7 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 KFY02470.1 - 0.0023 18.1 0.0 0.055 13.6 0.0 2.2 2 0 0 2 2 2 1 AAA domain Thymidylate_kin PF02223.17 KFY02470.1 - 0.0037 17.0 0.0 0.51 10.0 0.0 2.3 2 0 0 2 2 2 1 Thymidylate kinase Zeta_toxin PF06414.12 KFY02470.1 - 0.0099 15.2 0.2 0.069 12.4 0.0 2.0 2 0 0 2 2 2 1 Zeta toxin AAA PF00004.29 KFY02470.1 - 0.012 16.1 0.0 0.021 15.2 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 KFY02470.1 - 0.016 15.0 0.0 0.031 14.0 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain DUF2075 PF09848.9 KFY02470.1 - 0.016 14.4 0.0 0.023 14.0 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) NACHT PF05729.12 KFY02470.1 - 0.02 14.8 0.0 0.035 14.0 0.0 1.4 1 0 0 1 1 1 0 NACHT domain NTPase_1 PF03266.15 KFY02470.1 - 0.04 13.8 0.1 0.072 13.0 0.1 1.4 1 0 0 1 1 1 0 NTPase ABC_tran PF00005.27 KFY02470.1 - 0.042 14.4 0.0 0.081 13.4 0.0 1.5 1 0 0 1 1 1 0 ABC transporter T2SSE PF00437.20 KFY02470.1 - 0.043 12.9 0.0 0.068 12.2 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein KTI12 PF08433.10 KFY02470.1 - 0.052 13.0 0.0 0.093 12.2 0.0 1.4 1 0 0 1 1 1 0 Chromatin associated protein KTI12 AAA_24 PF13479.6 KFY02470.1 - 0.056 13.2 0.0 0.88 9.3 0.0 2.3 2 1 0 2 2 2 0 AAA domain APS_kinase PF01583.20 KFY02470.1 - 0.064 13.2 0.0 0.17 11.8 0.0 1.7 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA_30 PF13604.6 KFY02470.1 - 0.083 12.6 0.0 0.13 11.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 KFY02470.1 - 0.09 13.0 0.1 0.2 11.9 0.1 1.6 1 0 0 1 1 1 0 AAA domain cobW PF02492.19 KFY02470.1 - 0.091 12.3 0.1 0.21 11.2 0.1 1.6 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain TIP49 PF06068.13 KFY02470.1 - 0.094 11.9 0.0 0.15 11.2 0.0 1.2 1 0 0 1 1 1 0 TIP49 P-loop domain Viral_helicase1 PF01443.18 KFY02470.1 - 0.097 12.4 0.0 0.18 11.5 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase DnaB_C PF03796.15 KFY02470.1 - 0.11 11.9 0.0 0.14 11.5 0.0 1.2 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain TsaE PF02367.17 KFY02470.1 - 0.13 12.2 0.0 0.23 11.4 0.0 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_11 PF13086.6 KFY02470.1 - 0.15 11.8 0.0 0.24 11.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain ResIII PF04851.15 KFY02470.1 - 0.21 11.6 0.0 0.31 11.0 0.0 1.2 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit Mur_ligase_M PF08245.12 KFY02471.1 - 4.3e-05 23.6 0.7 0.00023 21.2 0.2 2.1 1 1 1 2 2 2 1 Mur ligase middle domain Pkinase PF00069.25 KFY02472.1 - 5.4e-71 239.1 0.0 1e-70 238.1 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFY02472.1 - 4.4e-49 167.1 0.0 6.9e-49 166.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KFY02472.1 - 0.00026 19.9 0.0 0.0005 19.0 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 KFY02472.1 - 0.025 13.9 0.0 0.19 11.0 0.0 2.0 2 0 0 2 2 2 0 Kinase-like Med15_fungi PF05397.12 KFY02472.1 - 0.06 13.6 0.2 0.15 12.4 0.2 1.6 1 0 0 1 1 1 0 Mediator complex subunit 15 Asp PF00026.23 KFY02474.1 - 2.9e-11 43.4 0.5 4.8e-11 42.7 0.5 1.3 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TMEM154 PF15102.6 KFY02474.1 - 0.019 14.9 0.0 0.04 13.8 0.0 1.6 1 0 0 1 1 1 0 TMEM154 protein family Orf78 PF06024.12 KFY02474.1 - 0.049 13.9 0.0 0.11 12.8 0.0 1.5 1 0 0 1 1 1 0 Orf78 (ac78) Amnionless PF14828.6 KFY02474.1 - 0.054 12.3 0.0 0.094 11.5 0.0 1.3 1 0 0 1 1 1 0 Amnionless DUF4690 PF15756.5 KFY02474.1 - 0.39 11.3 3.3 0.28 11.8 0.4 2.2 2 0 0 2 2 2 0 Small Novel Rich in Cartilage Glyco_hydro_88 PF07470.13 KFY02475.1 - 2.4e-15 56.5 0.2 3.4e-15 56.0 0.2 1.1 1 0 0 1 1 1 1 Glycosyl Hydrolase Family 88 AcetylCoA_hydro PF02550.15 KFY02476.1 - 2.5e-49 168.0 0.0 4.1e-49 167.2 0.0 1.4 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase N-terminal domain AcetylCoA_hyd_C PF13336.6 KFY02476.1 - 3.2e-41 140.8 0.0 5.3e-41 140.1 0.0 1.3 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase C-terminal domain CoA_trans PF01144.23 KFY02476.1 - 0.1 12.0 0.0 0.26 10.7 0.0 1.7 1 0 0 1 1 1 0 Coenzyme A transferase Glyco_hydro_35 PF01301.19 KFY02477.1 - 2.6e-89 300.0 0.0 4.1e-89 299.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 BetaGal_dom2 PF10435.9 KFY02477.1 - 1.4e-62 210.7 1.9 3.6e-62 209.4 1.9 1.7 1 0 0 1 1 1 1 Beta-galactosidase, domain 2 IF-2B PF01008.17 KFY02477.1 - 3.4e-59 200.4 10.7 5.6e-35 120.9 0.0 3.1 3 1 0 3 3 3 2 Initiation factor 2 subunit family BetaGal_dom4_5 PF13364.6 KFY02477.1 - 2.9e-53 179.3 8.5 2.8e-30 105.2 0.3 2.6 2 0 0 2 2 2 2 Beta-galactosidase jelly roll domain BetaGal_dom3 PF13363.6 KFY02477.1 - 6.7e-22 76.8 0.1 1.5e-21 75.7 0.1 1.6 1 0 0 1 1 1 1 Beta-galactosidase, domain 3 DUF4646 PF15496.6 KFY02477.1 - 0.0066 17.1 0.0 0.032 14.8 0.0 2.2 1 1 0 1 1 1 1 Domain of unknown function (DUF4646) DUF4849 PF16141.5 KFY02477.1 - 0.022 14.1 0.0 0.043 13.1 0.0 1.4 1 0 0 1 1 1 0 Putative glycoside hydrolase Family 18, chitinase_18 ESP PF16590.5 KFY02477.1 - 0.13 12.5 0.3 0.37 11.1 0.3 1.7 1 0 0 1 1 1 0 Exocrine gland-secreting peptide Cytadhesin_P30 PF07271.11 KFY02477.1 - 0.23 11.0 14.2 0.55 9.7 14.2 1.6 1 0 0 1 1 1 0 Cytadhesin P30/P32 Allexi_40kDa PF05549.11 KFY02477.1 - 0.27 10.7 1.5 0.52 9.8 0.1 2.1 2 0 0 2 2 2 0 Allexivirus 40kDa protein NIF PF03031.18 KFY02478.1 - 8.5e-57 191.3 0.0 1.5e-56 190.5 0.0 1.4 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase GREB1 PF15782.5 KFY02478.1 - 0.71 6.9 2.8 1.1 6.4 2.8 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer DUF3435 PF11917.8 KFY02480.1 - 1.4e-73 248.2 0.0 1.7e-73 248.0 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3435) zf-C2H2 PF00096.26 KFY02481.1 - 2.8e-17 62.1 27.2 3.5e-05 24.0 1.5 4.3 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KFY02481.1 - 5.6e-11 42.3 28.9 9.5e-07 29.0 0.2 5.2 5 0 0 5 5 5 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 KFY02481.1 - 1.1e-08 35.2 23.6 0.044 14.6 1.2 4.4 4 0 0 4 4 4 4 C2H2-type zinc finger zf-C2H2_aberr PF17017.5 KFY02481.1 - 0.04 14.0 11.3 0.59 10.2 0.4 3.0 1 1 2 3 3 3 0 Aberrant zinc-finger zf-C2H2_8 PF15909.5 KFY02481.1 - 0.047 14.0 9.1 2.1 8.7 4.9 3.0 1 1 1 2 2 2 0 C2H2-type zinc ribbon Zn-ribbon_8 PF09723.10 KFY02481.1 - 0.052 13.7 0.8 0.052 13.7 0.8 2.8 2 1 1 3 3 3 0 Zinc ribbon domain zf-C2H2_jaz PF12171.8 KFY02481.1 - 0.062 13.6 0.9 0.55 10.6 0.0 2.7 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KFY02481.1 - 0.63 10.5 6.7 22 5.6 0.4 3.9 4 0 0 4 4 4 0 Zinc-finger of C2H2 type FOXP-CC PF16159.5 KFY02481.1 - 2.8 8.7 12.4 9.3 7.0 0.5 4.1 1 1 3 4 4 4 0 FOXP coiled-coil domain TRAF6_Z2 PF18048.1 KFY02481.1 - 5 7.3 14.0 0.33 11.1 0.3 3.7 4 0 0 4 4 4 0 TNF receptor-associated factor 6 zinc finger 2 Dicty_CAR PF05462.11 KFY02483.1 - 3.8e-12 46.0 17.1 1.2e-11 44.3 11.1 2.1 2 0 0 2 2 2 2 Slime mold cyclic AMP receptor Git3 PF11710.8 KFY02483.1 - 6.3e-09 35.9 12.8 6.3e-09 35.9 12.8 1.9 2 0 0 2 2 2 1 G protein-coupled glucose receptor regulating Gpa2 7tm_1 PF00001.21 KFY02483.1 - 8.2e-06 25.3 9.5 1.1e-05 25.0 9.5 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) THOC2_N PF16134.5 KFY02485.1 - 7.8e-242 804.4 0.0 1e-241 804.1 0.0 1.1 1 0 0 1 1 1 1 THO complex subunit 2 N-terminus Tho2 PF11262.8 KFY02485.1 - 9e-101 337.0 0.0 1.6e-100 336.2 0.0 1.4 1 0 0 1 1 1 1 Transcription factor/nuclear export subunit protein 2 Thoc2 PF11732.8 KFY02485.1 - 1.8e-28 98.4 0.0 5.5e-28 96.8 0.0 1.9 1 0 0 1 1 1 1 Transcription- and export-related complex subunit Abhydrolase_1 PF00561.20 KFY02486.1 - 3.9e-41 141.4 0.2 4.8e-41 141.1 0.2 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KFY02486.1 - 6.6e-06 26.9 0.5 1e-05 26.3 0.5 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Say1_Mug180 PF10340.9 KFY02486.1 - 0.068 12.0 0.0 0.083 11.7 0.0 1.1 1 0 0 1 1 1 0 Steryl acetyl hydrolase HATPase_c PF02518.26 KFY02488.1 - 4.2e-25 88.4 0.2 8.9e-25 87.4 0.2 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PAS_3 PF08447.12 KFY02488.1 - 2.1e-21 76.0 3.0 3.3e-11 43.3 1.7 3.7 3 0 0 3 3 3 3 PAS fold Response_reg PF00072.24 KFY02488.1 - 3.7e-20 72.2 0.1 5.4e-19 68.4 0.0 2.4 2 0 0 2 2 2 1 Response regulator receiver domain HisKA PF00512.25 KFY02488.1 - 1.5e-18 66.6 0.0 4.4e-18 65.1 0.0 1.9 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PAS_4 PF08448.10 KFY02488.1 - 1.4e-09 38.1 0.2 1e-05 25.7 0.2 3.7 3 0 0 3 3 3 2 PAS fold PAS_9 PF13426.7 KFY02488.1 - 3.6e-09 36.8 0.0 0.0015 18.7 0.0 3.5 3 0 0 3 3 3 2 PAS domain PAS PF00989.25 KFY02488.1 - 1.6e-08 34.5 0.0 0.0064 16.5 0.0 3.0 2 0 0 2 2 2 2 PAS fold PAS_8 PF13188.7 KFY02488.1 - 0.00065 19.7 0.0 0.12 12.4 0.0 2.6 2 0 0 2 2 2 1 PAS domain Carb_kinase PF01256.17 KFY02490.1 - 6e-56 189.7 0.0 8.4e-56 189.2 0.0 1.1 1 0 0 1 1 1 1 Carbohydrate kinase HK PF02110.15 KFY02490.1 - 0.022 14.2 0.0 0.035 13.5 0.0 1.3 1 0 0 1 1 1 0 Hydroxyethylthiazole kinase family Phos_pyr_kin PF08543.12 KFY02490.1 - 0.2 11.0 0.0 0.54 9.6 0.0 1.7 1 1 0 1 1 1 0 Phosphomethylpyrimidine kinase PARP PF00644.20 KFY02491.1 - 7.5e-11 42.0 0.3 5.3e-10 39.2 0.3 2.1 2 0 0 2 2 2 1 Poly(ADP-ribose) polymerase catalytic domain UQ_con PF00179.26 KFY02491.1 - 3e-08 33.4 0.0 6.8e-08 32.3 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Sds3 PF08598.11 KFY02492.1 - 2.8e-22 79.8 0.5 4.3e-22 79.2 0.5 1.3 1 0 0 1 1 1 1 Sds3-like Nop PF01798.18 KFY02493.1 - 2.5e-79 266.0 0.1 2.5e-79 266.0 0.1 2.5 2 1 1 3 3 3 1 snoRNA binding domain, fibrillarin NOP5NT PF08156.13 KFY02493.1 - 6.3e-21 74.5 2.2 6.3e-21 74.5 2.2 3.3 3 1 0 3 3 3 1 NOP5NT (NUC127) domain DUF3653 PF12375.8 KFY02493.1 - 0.084 13.0 0.2 17 5.6 0.0 2.6 2 0 0 2 2 2 0 Phage protein vATP-synt_AC39 PF01992.16 KFY02494.1 - 9e-109 364.0 0.0 1e-108 363.9 0.0 1.0 1 0 0 1 1 1 1 ATP synthase (C/AC39) subunit Ribosomal_S15 PF00312.22 KFY02495.1 - 1e-25 89.7 0.6 3.2e-25 88.1 0.6 1.9 1 0 0 1 1 1 1 Ribosomal protein S15 Ribosomal_S2 PF00318.20 KFY02496.1 - 2.8e-27 95.3 0.6 7.4e-16 58.0 0.1 2.1 1 1 1 2 2 2 2 Ribosomal protein S2 40S_SA_C PF16122.5 KFY02496.1 - 8.8e-11 43.0 14.1 2e-10 41.9 14.1 1.6 1 0 0 1 1 1 1 40S ribosomal protein SA C-terminus zf-RING_2 PF13639.6 KFY02499.1 - 4.1e-10 39.8 4.4 8.4e-10 38.8 4.4 1.6 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 KFY02499.1 - 2e-08 34.4 4.3 4.4e-08 33.3 4.3 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 KFY02499.1 - 4.1e-06 26.8 0.5 7.8e-06 25.9 0.5 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_3 PF13920.6 KFY02499.1 - 2.2e-05 24.2 1.8 4.1e-05 23.3 1.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KFY02499.1 - 4.8e-05 23.1 3.6 9.2e-05 22.2 3.6 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 KFY02499.1 - 9.4e-05 22.3 2.9 0.00016 21.5 2.9 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 KFY02499.1 - 0.00014 21.6 6.8 0.00042 20.1 6.8 1.8 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KFY02499.1 - 0.00043 20.1 4.1 0.00076 19.3 4.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KFY02499.1 - 0.003 17.5 4.5 0.0074 16.3 4.5 1.7 1 0 0 1 1 1 1 RING-type zinc-finger FANCL_C PF11793.8 KFY02499.1 - 0.0048 17.1 5.6 0.07 13.3 5.6 2.3 1 1 0 1 1 1 1 FANCL C-terminal domain zf-RING_11 PF17123.5 KFY02499.1 - 0.01 15.6 1.5 0.024 14.4 1.5 1.7 1 1 0 1 1 1 0 RING-like zinc finger zf-P11 PF03854.14 KFY02499.1 - 0.063 12.9 1.3 0.15 11.7 1.3 1.6 1 0 0 1 1 1 0 P-11 zinc finger Zn_ribbon_17 PF17120.5 KFY02499.1 - 0.1 12.3 1.7 0.22 11.2 1.7 1.5 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type DUF3533 PF12051.8 KFY02499.1 - 0.61 9.0 2.5 1.1 8.1 2.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3533) Macoilin PF09726.9 KFY02499.1 - 9.5 4.6 10.3 17 3.8 10.3 1.4 1 0 0 1 1 1 0 Macoilin family MFS_1 PF07690.16 KFY02501.1 - 3.2e-39 134.9 26.6 3.2e-39 134.9 26.6 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily Tweety PF04906.13 KFY02501.1 - 0.022 13.5 1.2 0.038 12.7 1.2 1.3 1 0 0 1 1 1 0 Tweety DUF4181 PF13789.6 KFY02501.1 - 6.9 7.0 7.0 5.3 7.4 0.5 2.8 2 1 0 2 2 2 0 Domain of unknown function (DUF4181) Zn_clus PF00172.18 KFY02502.1 - 8e-07 29.1 10.4 1.2e-06 28.5 10.4 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KFY02502.1 - 5.9e-06 25.5 0.1 1.3e-05 24.3 0.1 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Peptidase_C48 PF02902.19 KFY02508.1 - 1.6e-05 24.8 0.0 3.6e-05 23.7 0.0 1.6 1 1 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain zf-RING_9 PF13901.6 KFY02508.1 - 0.11 12.4 3.0 0.2 11.6 3.0 1.3 1 0 0 1 1 1 0 Putative zinc-RING and/or ribbon PHD PF00628.29 KFY02508.1 - 0.17 11.8 4.9 0.33 10.9 4.9 1.5 1 0 0 1 1 1 0 PHD-finger AT_hook PF02178.19 KFY02508.1 - 0.89 9.6 9.9 0.19 11.7 5.0 2.7 2 0 0 2 2 2 0 AT hook motif SepSecS PF05889.13 KFY02509.1 - 0.16 10.6 0.5 0.45 9.2 0.0 1.7 1 1 1 2 2 2 0 O-phosphoseryl-tRNA(Sec) selenium transferase, SepSecS Kinesin PF00225.23 KFY02520.1 - 1.7e-79 267.2 0.0 2.8e-79 266.5 0.0 1.3 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 KFY02520.1 - 7.5e-21 74.6 0.0 1.4e-20 73.7 0.0 1.5 1 0 0 1 1 1 1 Microtubule binding HHH_5 PF14520.6 KFY02520.1 - 0.00094 19.7 0.2 0.0048 17.5 0.2 2.1 1 1 0 1 1 1 1 Helix-hairpin-helix domain HHH PF00633.23 KFY02520.1 - 0.01 15.6 0.3 1.9 8.5 0.0 2.8 2 0 0 2 2 2 0 Helix-hairpin-helix motif HHH_3 PF12836.7 KFY02520.1 - 0.012 15.9 0.0 0.038 14.2 0.0 1.8 1 0 0 1 1 1 0 Helix-hairpin-helix motif PBP1_TM PF14812.6 KFY02520.1 - 0.035 14.5 1.1 0.1 13.0 1.1 1.8 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal AIM24 PF01987.17 KFY02521.1 - 2.3e-50 171.2 0.1 3.5e-50 170.6 0.1 1.3 1 0 0 1 1 1 1 Mitochondrial biogenesis AIM24 MFS_1 PF07690.16 KFY02521.1 - 5e-28 98.0 71.1 5.5e-26 91.3 47.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily SBF PF01758.16 KFY02522.1 - 7.5e-50 169.3 14.6 7.5e-50 169.3 14.6 2.2 3 1 0 3 3 3 1 Sodium Bile acid symporter family DUF2897 PF11446.8 KFY02522.1 - 2.3 8.1 4.2 7 6.6 4.2 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) Rhodanese PF00581.20 KFY02523.1 - 1.3e-06 28.9 0.0 1.7e-06 28.5 0.0 1.2 1 0 0 1 1 1 1 Rhodanese-like domain HlyD_D4 PF16572.5 KFY02523.1 - 0.15 12.0 0.1 0.27 11.1 0.1 1.4 1 0 0 1 1 1 0 Long alpha hairpin domain of cation efflux system protein, CusB DUF5616 PF18481.1 KFY02523.1 - 0.18 12.1 0.0 0.24 11.7 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5616) Redoxin PF08534.10 KFY02525.1 - 7.3e-26 90.6 0.0 8.8e-26 90.4 0.0 1.1 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.21 KFY02525.1 - 3e-05 23.9 0.0 3.8e-05 23.6 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family 2-Hacid_dh_C PF02826.19 KFY02529.1 - 8.5e-53 178.3 0.0 1.3e-52 177.7 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 KFY02529.1 - 2.3e-12 46.7 0.0 2.6e-12 46.6 0.0 1.0 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 KFY02529.1 - 2.7e-05 24.4 0.0 4e-05 23.9 0.0 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase IlvN PF07991.12 KFY02529.1 - 0.0002 20.9 0.0 0.00029 20.4 0.0 1.2 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain Shikimate_DH PF01488.20 KFY02529.1 - 0.025 14.6 0.1 0.079 13.0 0.0 1.9 2 1 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase F420_oxidored PF03807.17 KFY02529.1 - 0.05 14.2 0.0 0.097 13.3 0.0 1.5 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent 3HCDH_N PF02737.18 KFY02529.1 - 0.058 13.3 0.0 0.085 12.7 0.0 1.2 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ApbA PF02558.16 KFY02529.1 - 0.086 12.5 0.0 0.13 11.9 0.0 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA AdoHcyase_NAD PF00670.21 KFY02529.1 - 0.12 12.4 0.0 0.23 11.5 0.0 1.5 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Glu_dehyd_C PF16912.5 KFY02529.1 - 0.14 11.6 0.0 0.22 11.0 0.0 1.3 1 0 0 1 1 1 0 Glucose dehydrogenase C-terminus MFS_1 PF07690.16 KFY02530.1 - 5.8e-33 114.3 31.8 8.3e-33 113.8 31.8 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Glyco_hydro_47 PF01532.20 KFY02531.1 - 1.6e-166 554.8 0.0 1.9e-166 554.5 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 DNA_pol3_a_NII PF11490.8 KFY02531.1 - 4.5 7.2 7.5 8.9 6.2 7.5 1.3 1 0 0 1 1 1 0 DNA polymerase III polC-type N-terminus II Clathrin PF00637.20 KFY02532.1 - 3.4e-18 65.9 0.7 1.7e-17 63.7 0.1 2.4 2 1 0 2 2 2 1 Region in Clathrin and VPS WD40_like PF17005.5 KFY02532.1 - 0.0016 17.9 0.0 0.0039 16.6 0.0 1.6 1 1 0 1 1 1 1 WD40-like domain Vps39_1 PF10366.9 KFY02532.1 - 0.0094 16.2 0.2 0.046 14.0 0.0 2.2 2 0 0 2 2 2 1 Vacuolar sorting protein 39 domain 1 zf-RING_5 PF14634.6 KFY02532.1 - 0.077 13.0 0.2 0.15 12.1 0.2 1.4 1 0 0 1 1 1 0 zinc-RING finger domain SDA1 PF05285.12 KFY02532.1 - 0.093 12.1 6.4 0.049 13.1 4.0 1.7 2 0 0 2 2 2 0 SDA1 zf-RING_11 PF17123.5 KFY02532.1 - 0.15 11.9 0.5 0.32 10.8 0.5 1.5 1 0 0 1 1 1 0 RING-like zinc finger SPX PF03105.19 KFY02532.1 - 2.5 7.9 8.1 3.5 7.4 2.1 2.3 2 0 0 2 2 2 0 SPX domain DUF155 PF02582.14 KFY02533.1 - 9.5e-46 156.1 0.0 1.7e-45 155.2 0.0 1.5 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 ANAPC1 PF12859.7 KFY02533.1 - 1.3e-38 132.5 0.6 7e-38 130.1 0.6 2.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 1 Ank_4 PF13637.6 KFY02534.1 - 1e-14 54.7 0.6 1.7e-08 34.8 0.1 2.7 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 KFY02534.1 - 2.1e-14 53.9 0.1 2.7e-14 53.5 0.1 1.1 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KFY02534.1 - 5.8e-13 48.8 0.6 1.1e-08 35.2 0.1 2.9 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 KFY02534.1 - 3e-12 46.4 0.4 4.1e-08 33.3 0.6 2.4 2 0 0 2 2 2 2 Ankyrin repeat Ank_3 PF13606.6 KFY02534.1 - 5.1e-11 41.8 0.0 1.1e-05 25.4 0.1 2.9 3 0 0 3 3 3 2 Ankyrin repeat ECH_1 PF00378.20 KFY02535.1 - 9.1e-40 136.5 0.7 3.8e-36 124.7 0.4 2.9 2 1 0 2 2 2 2 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KFY02535.1 - 5.7e-28 98.4 0.2 1.6e-23 83.8 0.0 2.1 2 0 0 2 2 2 2 Enoyl-CoA hydratase/isomerase Cpn60_TCP1 PF00118.24 KFY02536.1 - 1.1e-158 528.9 0.1 1.3e-158 528.7 0.1 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Herpes_UL6 PF01763.16 KFY02536.1 - 0.026 13.1 0.0 0.039 12.5 0.0 1.2 1 0 0 1 1 1 0 Herpesvirus UL6 like Prenylcys_lyase PF07156.14 KFY02537.1 - 9.2e-80 268.4 0.0 1.5e-63 215.1 0.0 2.1 1 1 1 2 2 2 2 Prenylcysteine lyase Amino_oxidase PF01593.24 KFY02537.1 - 6.4e-14 52.1 0.0 2.6e-13 50.1 0.0 1.7 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 KFY02537.1 - 4.5e-13 49.2 0.0 8.4e-13 48.4 0.0 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KFY02537.1 - 1.1e-09 38.3 0.1 1.3e-06 28.2 0.2 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 KFY02537.1 - 0.00012 22.1 0.1 0.00059 19.9 0.0 2.0 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.14 KFY02537.1 - 0.00017 20.9 0.0 0.003 16.9 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KFY02537.1 - 0.0046 16.2 0.1 0.0095 15.2 0.1 1.5 1 0 0 1 1 1 1 Thi4 family Pyr_redox PF00070.27 KFY02537.1 - 0.0049 17.4 0.1 0.22 12.1 0.1 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.16 KFY02537.1 - 0.027 14.1 0.2 0.093 12.4 0.1 1.8 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA Ribosomal_S26e PF01283.19 KFY02538.1 - 1.2e-51 173.7 7.0 1.4e-51 173.4 7.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S26e zf_CopZ PF18423.1 KFY02538.1 - 0.021 14.8 0.5 0.061 13.3 0.0 2.0 2 0 0 2 2 2 0 Zinc binding domain DUF1918 PF08940.11 KFY02538.1 - 0.086 12.5 0.0 0.17 11.5 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1918) Fer4_2 PF12797.7 KFY02538.1 - 0.15 12.2 2.7 0.36 11.0 0.9 2.1 2 0 0 2 2 2 0 4Fe-4S binding domain DUF4668 PF15701.5 KFY02538.1 - 0.17 11.7 0.4 0.26 11.1 0.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4668) SF1-HH PF16275.5 KFY02538.1 - 0.33 11.3 2.9 0.52 10.7 2.9 1.5 1 1 0 1 1 1 0 Splicing factor 1 helix-hairpin domain Ribosomal_S27 PF01599.19 KFY02539.1 - 7.4e-27 93.2 2.2 7.4e-27 93.2 2.2 2.4 3 0 0 3 3 3 1 Ribosomal protein S27a IBR PF01485.21 KFY02539.1 - 0.021 15.1 0.9 0.029 14.6 0.6 1.7 1 1 0 1 1 1 0 IBR domain, a half RING-finger domain Glyco_hydro_18 PF00704.28 KFY02540.1 - 2.4e-87 293.6 0.1 2.8e-87 293.4 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 DnaJ PF00226.31 KFY02541.1 - 1.2e-07 31.8 0.4 3.6e-07 30.2 0.4 1.9 1 0 0 1 1 1 1 DnaJ domain Nfu_N PF08712.11 KFY02546.1 - 1.4e-29 101.9 0.0 4.1e-29 100.5 0.0 1.8 2 0 0 2 2 2 1 Scaffold protein Nfu/NifU N terminal NifU PF01106.17 KFY02546.1 - 4.1e-26 90.9 0.1 6.6e-26 90.3 0.1 1.3 1 0 0 1 1 1 1 NifU-like domain YojJ PF10372.9 KFY02546.1 - 0.015 15.3 0.1 0.07 13.2 0.1 1.9 2 0 0 2 2 2 0 Bacterial membrane-spanning protein N-terminus Aminotran_3 PF00202.21 KFY02552.1 - 6.9e-60 202.8 0.4 4.6e-40 137.5 0.0 2.2 2 0 0 2 2 2 2 Aminotransferase class-III DGC PF08859.11 KFY02552.1 - 0.14 12.2 0.1 0.47 10.6 0.1 1.9 1 0 0 1 1 1 0 DGC domain DUF515 PF04415.12 KFY02552.1 - 0.28 9.5 3.5 0.44 8.9 3.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF515) Exonuc_VII_L PF02601.15 KFY02552.1 - 5.8 6.4 6.9 7.8 6.0 5.8 1.6 2 0 0 2 2 2 0 Exonuclease VII, large subunit DNA_repr_REX1B PF14966.6 KFY02552.1 - 6.3 7.5 8.8 8.8 7.1 5.6 2.8 2 1 0 2 2 2 0 DNA repair REX1-B Pkinase PF00069.25 KFY02553.1 - 7.2e-05 22.3 0.0 0.0002 20.9 0.0 1.8 1 0 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 KFY02553.1 - 0.00024 20.0 0.0 0.00024 20.0 0.0 2.4 3 0 0 3 3 3 1 Fungal protein kinase APH PF01636.23 KFY02553.1 - 0.0092 15.9 0.1 0.0092 15.9 0.1 3.4 3 1 1 4 4 4 1 Phosphotransferase enzyme family CwsA PF10814.8 KFY02555.1 - 0.18 12.0 1.8 0.23 11.6 1.8 1.2 1 0 0 1 1 1 0 Cell wall synthesis protein CwsA APH PF01636.23 KFY02556.1 - 4.3e-15 56.3 0.0 8.6e-15 55.3 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KFY02556.1 - 0.017 14.7 0.0 0.044 13.4 0.0 1.6 1 1 0 1 1 1 0 Choline/ethanolamine kinase Cytokin_check_N PF10407.9 KFY02558.1 - 5e-06 26.4 0.0 1e-05 25.4 0.0 1.4 1 0 0 1 1 1 1 Cdc14 phosphatase binding protein N-terminus AAA PF00004.29 KFY02559.1 - 1e-26 93.9 0.0 2e-26 93.0 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 KFY02559.1 - 2.6e-06 27.3 0.0 0.00028 20.7 0.0 2.2 1 1 1 2 2 2 1 AAA domain RuvB_N PF05496.12 KFY02559.1 - 0.0003 20.6 0.1 0.001 18.8 0.0 1.8 1 1 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 KFY02559.1 - 0.00055 20.0 0.0 0.0011 19.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 KFY02559.1 - 0.0011 19.4 1.9 0.0053 17.2 1.9 2.0 1 1 0 1 1 1 1 AAA ATPase domain RNA_helicase PF00910.22 KFY02559.1 - 0.0012 19.3 0.0 0.003 17.9 0.0 1.8 1 0 0 1 1 1 1 RNA helicase AAA_2 PF07724.14 KFY02559.1 - 0.0055 16.8 0.0 0.055 13.6 0.0 2.4 2 1 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_33 PF13671.6 KFY02559.1 - 0.0074 16.5 0.0 0.015 15.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 KFY02559.1 - 0.0074 16.6 0.6 0.065 13.5 0.7 2.5 2 1 0 2 2 2 1 AAA domain AAA_25 PF13481.6 KFY02559.1 - 0.011 15.3 0.3 0.036 13.6 0.3 1.8 1 1 0 1 1 1 0 AAA domain NACHT PF05729.12 KFY02559.1 - 0.013 15.4 0.2 0.034 14.1 0.2 1.8 1 1 0 1 1 1 0 NACHT domain TIP49 PF06068.13 KFY02559.1 - 0.015 14.5 0.1 0.023 13.9 0.1 1.2 1 0 0 1 1 1 0 TIP49 P-loop domain AAA_18 PF13238.6 KFY02559.1 - 0.016 15.7 0.0 0.037 14.6 0.0 1.7 1 1 0 1 1 1 0 AAA domain CdiI_2 PF18593.1 KFY02559.1 - 0.021 15.5 0.0 0.28 11.9 0.0 2.5 2 0 0 2 2 2 0 CdiI immunity protein AAA_28 PF13521.6 KFY02559.1 - 0.021 15.1 0.0 0.042 14.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain ArsA_ATPase PF02374.15 KFY02559.1 - 0.023 13.9 0.3 0.08 12.1 0.1 1.8 1 1 1 2 2 2 0 Anion-transporting ATPase AAA_11 PF13086.6 KFY02559.1 - 0.054 13.3 0.0 0.099 12.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 KFY02559.1 - 0.056 13.2 0.1 0.22 11.2 0.1 2.0 1 1 1 2 2 2 0 IstB-like ATP binding protein PhoH PF02562.16 KFY02559.1 - 0.071 12.6 0.0 0.13 11.7 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein ATPase PF06745.13 KFY02559.1 - 0.088 12.1 0.5 11 5.2 0.1 2.2 1 1 1 2 2 2 0 KaiC AAA_19 PF13245.6 KFY02559.1 - 0.12 12.7 0.0 0.38 11.1 0.0 1.8 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 KFY02559.1 - 0.13 12.2 0.0 0.29 11.1 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE DUF2075 PF09848.9 KFY02559.1 - 0.17 11.1 0.0 0.31 10.3 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Telomerase_RBD PF12009.8 KFY02560.1 - 6.2e-50 168.8 0.1 1.3e-49 167.7 0.1 1.6 1 0 0 1 1 1 1 Telomerase ribonucleoprotein complex - RNA binding domain RVT_1 PF00078.27 KFY02560.1 - 9.9e-14 51.4 0.0 3.5e-11 43.1 0.0 2.3 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) RhoGEF PF00621.20 KFY02561.1 - 2.1e-33 116.1 0.4 9.1e-33 114.0 0.0 2.2 2 1 0 2 2 2 1 RhoGEF domain BAR PF03114.18 KFY02561.1 - 3.4e-07 30.1 1.6 3.4e-07 30.1 1.6 2.0 2 0 0 2 2 2 1 BAR domain TPR_12 PF13424.6 KFY02562.1 - 6.3e-29 100.1 13.3 3.2e-14 53.0 2.9 2.1 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_10 PF13374.6 KFY02562.1 - 5.2e-25 86.6 3.0 4.1e-10 39.2 0.2 3.2 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_14 PF13428.6 KFY02562.1 - 5.9e-13 48.5 0.9 0.00083 20.0 0.0 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 KFY02562.1 - 6.9e-13 47.7 0.1 0.0018 18.3 0.0 3.1 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 KFY02562.1 - 2.5e-12 45.9 0.1 0.0026 17.7 0.0 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.6 KFY02562.1 - 2.6e-10 39.6 0.5 0.006 16.5 0.1 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 KFY02562.1 - 2.9e-10 40.5 3.4 1.5e-05 25.4 0.5 2.2 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.6 KFY02562.1 - 2.6e-09 36.6 0.6 0.01 15.5 0.0 3.2 3 0 0 3 3 3 3 TPR repeat ANAPC3 PF12895.7 KFY02562.1 - 3.4e-09 36.8 0.2 0.0014 18.8 0.0 2.2 1 1 1 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.6 KFY02562.1 - 4.9e-09 36.3 1.9 0.051 14.2 0.1 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat PPR PF01535.20 KFY02562.1 - 9.7e-09 34.9 0.0 0.089 13.1 0.0 3.1 3 0 0 3 3 3 2 PPR repeat TPR_20 PF14561.6 KFY02562.1 - 1.1e-08 35.3 3.8 0.0033 17.7 0.1 2.8 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 KFY02562.1 - 1.8e-08 33.8 0.2 0.064 13.1 0.0 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 KFY02562.1 - 2.2e-08 34.6 0.1 0.049 14.3 0.0 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat PPR_1 PF12854.7 KFY02562.1 - 1.9e-05 24.3 3.3 1.3 8.8 0.1 3.2 3 0 0 3 3 3 2 PPR repeat TPR_4 PF07721.14 KFY02562.1 - 6.2e-05 23.2 12.2 0.047 14.3 2.0 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat Fis1_TPR_N PF14852.6 KFY02562.1 - 0.0003 20.4 3.4 4.8 7.0 0.1 3.2 3 0 0 3 3 3 0 Fis1 N-terminal tetratricopeptide repeat PPR_2 PF13041.6 KFY02562.1 - 0.00033 20.8 0.1 7.3 6.9 0.0 3.1 3 0 0 3 3 3 0 PPR repeat family TPR_MalT PF17874.1 KFY02562.1 - 0.00034 20.1 4.8 0.00046 19.7 4.8 1.2 1 0 0 1 1 1 1 MalT-like TPR region Plant_NMP1 PF06694.11 KFY02562.1 - 0.00077 18.7 0.3 0.11 11.6 0.0 2.5 1 1 2 3 3 3 1 Plant nuclear matrix protein 1 (NMP1) Vps39_1 PF10366.9 KFY02562.1 - 0.0016 18.7 0.6 1.4 9.2 0.2 2.7 1 1 1 2 2 2 1 Vacuolar sorting protein 39 domain 1 TPR_5 PF12688.7 KFY02562.1 - 0.0019 18.4 2.8 0.015 15.6 0.9 2.2 1 1 1 2 2 2 1 Tetratrico peptide repeat Clathrin PF00637.20 KFY02562.1 - 0.0042 17.0 0.2 2.5 8.0 0.0 2.9 3 0 0 3 3 3 1 Region in Clathrin and VPS MRVI1 PF05781.12 KFY02562.1 - 0.0047 15.7 1.8 0.0061 15.3 1.8 1.1 1 0 0 1 1 1 1 MRVI1 protein WbqC PF08889.11 KFY02562.1 - 0.0072 16.3 0.1 0.49 10.3 0.1 2.0 1 1 1 2 2 2 2 WbqC-like protein family PknG_TPR PF16918.5 KFY02562.1 - 0.0094 14.7 1.2 0.091 11.5 0.6 2.2 1 1 1 2 2 2 2 Protein kinase G tetratricopeptide repeat RPN7 PF10602.9 KFY02562.1 - 0.013 15.3 1.0 0.9 9.2 0.2 2.2 1 1 1 2 2 2 0 26S proteasome subunit RPN7 VWA_3_C PF18571.1 KFY02562.1 - 0.014 15.3 7.3 2.4 8.1 0.4 3.2 3 0 0 3 3 3 0 von Willebrand factor type A C-terminal domain PhnJ PF06007.11 KFY02562.1 - 0.024 13.6 0.0 12 4.8 0.0 2.8 1 1 2 3 3 3 0 Phosphonate metabolism protein PhnJ SPG48 PF14764.6 KFY02562.1 - 0.038 14.5 0.1 36 4.9 0.0 2.9 3 0 0 3 3 3 0 AP-5 complex subunit, vesicle trafficking SPOB_a PF14689.6 KFY02562.1 - 0.044 13.5 2.8 24 4.7 0.1 3.1 3 0 0 3 3 3 0 Sensor_kinase_SpoOB-type, alpha-helical domain ATP13 PF12921.7 KFY02562.1 - 0.05 13.5 0.0 6.7 6.6 0.0 2.3 1 1 1 2 2 2 0 Mitochondrial ATPase expression ATG16 PF08614.11 KFY02562.1 - 0.071 13.3 3.9 0.3 11.3 3.9 1.8 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) MT PF12777.7 KFY02562.1 - 0.082 11.9 1.9 1.3 7.9 1.1 2.6 1 1 1 2 2 2 0 Microtubule-binding stalk of dynein motor ArAE_2_N PF10337.9 KFY02562.1 - 0.091 11.8 0.5 14 4.6 0.0 2.7 1 1 2 3 3 3 0 Putative ER transporter, 6TM, N-terminal DUF745 PF05335.13 KFY02562.1 - 0.27 10.9 7.9 4.1 7.1 8.1 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF745) RPN6_N PF18055.1 KFY02562.1 - 0.32 11.4 3.3 0.44 10.9 0.7 1.9 1 1 1 2 2 2 0 26S proteasome regulatory subunit RPN6 N-terminal domain CSTF_C PF14304.6 KFY02562.1 - 0.97 9.1 8.8 21 4.8 0.6 3.2 3 0 0 3 3 3 0 Transcription termination and cleavage factor C-terminal Patatin PF01734.22 KFY02563.1 - 1.3e-14 54.9 0.0 3.6e-14 53.4 0.0 1.8 1 0 0 1 1 1 1 Patatin-like phospholipase zf-C3HC4_2 PF13923.6 KFY02563.1 - 0.022 14.6 4.4 0.064 13.1 4.4 1.9 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KFY02563.1 - 0.038 13.9 8.8 0.12 12.2 8.8 2.0 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KFY02563.1 - 1.4 8.8 13.8 0.039 13.8 7.1 2.0 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 KFY02563.1 - 1.4 9.1 9.3 5 7.4 9.3 2.1 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 KFY02563.1 - 1.8 8.5 8.5 6.3 6.7 8.5 2.0 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 KFY02563.1 - 3.7 7.6 10.9 12 5.9 10.9 1.9 1 0 0 1 1 1 0 zinc-RING finger domain DnaJ PF00226.31 KFY02564.1 - 5.4e-17 61.7 0.4 1.7e-16 60.1 0.4 2.0 1 0 0 1 1 1 1 DnaJ domain DUF812 PF05667.11 KFY02568.1 - 0.0056 15.6 3.9 0.0081 15.1 3.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF812) DUF641 PF04859.12 KFY02568.1 - 0.0076 16.6 0.1 0.014 15.7 0.1 1.5 1 0 0 1 1 1 1 Plant protein of unknown function (DUF641) Fib_alpha PF08702.10 KFY02568.1 - 0.011 15.9 0.2 0.02 15.1 0.2 1.5 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family IMD PF08397.11 KFY02568.1 - 0.013 14.9 2.7 0.019 14.4 2.7 1.2 1 0 0 1 1 1 0 IRSp53/MIM homology domain DUF3450 PF11932.8 KFY02568.1 - 0.014 14.7 0.4 0.023 14.0 0.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) STAT_alpha PF01017.20 KFY02568.1 - 0.032 14.1 3.3 0.053 13.4 3.3 1.4 1 0 0 1 1 1 0 STAT protein, all-alpha domain Phage_GP20 PF06810.11 KFY02568.1 - 0.087 12.6 0.5 0.14 11.9 0.5 1.4 1 0 0 1 1 1 0 Phage minor structural protein GP20 ADIP PF11559.8 KFY02568.1 - 0.09 12.9 3.5 0.15 12.2 3.5 1.3 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding DUF4618 PF15397.6 KFY02568.1 - 0.14 11.5 4.1 2.6 7.4 0.4 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4618) TMF_DNA_bd PF12329.8 KFY02569.1 - 0.0021 18.0 3.5 0.01 15.8 0.3 3.1 3 0 0 3 3 3 1 TATA element modulatory factor 1 DNA binding bZIP_1 PF00170.21 KFY02569.1 - 0.0022 18.1 10.4 0.6 10.2 0.2 3.4 3 0 0 3 3 3 2 bZIP transcription factor ALIX_LYPXL_bnd PF13949.6 KFY02569.1 - 0.0047 16.3 2.0 0.0047 16.3 2.0 1.7 2 0 0 2 2 2 1 ALIX V-shaped domain binding to HIV E2R135 PF11570.8 KFY02569.1 - 0.016 15.5 0.4 0.55 10.5 0.0 2.5 2 0 0 2 2 2 0 Coiled-coil receptor-binding R-domain of colicin E2 CaMKII_AD PF08332.10 KFY02569.1 - 0.061 13.5 0.4 1.3 9.2 0.1 2.3 2 0 0 2 2 2 0 Calcium/calmodulin dependent protein kinase II association domain JIP_LZII PF16471.5 KFY02569.1 - 0.067 13.4 6.5 5.3 7.3 0.7 3.5 3 0 0 3 3 3 0 JNK-interacting protein leucine zipper II Mto2_bdg PF12808.7 KFY02569.1 - 0.11 12.8 0.5 0.11 12.8 0.5 4.1 3 1 1 4 4 4 0 Micro-tubular organiser Mto1 C-term Mto2-binding region GAS PF13851.6 KFY02569.1 - 0.19 11.0 14.1 0.83 9.0 0.4 3.1 2 1 1 3 3 3 0 Growth-arrest specific micro-tubule binding Cnn_1N PF07989.11 KFY02569.1 - 0.21 11.7 6.7 5.9 7.1 0.1 3.2 2 1 0 2 2 2 0 Centrosomin N-terminal motif 1 FPP PF05911.11 KFY02569.1 - 0.23 9.6 11.3 0.053 11.7 8.0 1.5 2 0 0 2 2 2 0 Filament-like plant protein, long coiled-coil DUF3450 PF11932.8 KFY02569.1 - 0.25 10.6 8.6 0.46 9.8 1.2 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3450) Fez1 PF06818.15 KFY02569.1 - 0.36 11.3 10.4 0.7 10.3 4.7 2.3 2 0 0 2 2 2 0 Fez1 DUF641 PF04859.12 KFY02569.1 - 0.41 11.0 8.2 1.6 9.1 3.7 2.6 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) Fib_alpha PF08702.10 KFY02569.1 - 0.6 10.3 9.0 20 5.3 9.0 2.7 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family ZapB PF06005.12 KFY02569.1 - 0.81 10.2 12.9 1.3 9.6 4.4 3.4 3 0 0 3 3 3 0 Cell division protein ZapB DUF1664 PF07889.12 KFY02569.1 - 1.3 9.1 7.8 24 5.0 0.5 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) TMPIT PF07851.13 KFY02569.1 - 2.1 7.5 6.3 0.14 11.3 0.3 2.1 3 0 0 3 3 3 0 TMPIT-like protein KASH_CCD PF14662.6 KFY02569.1 - 2.2 8.1 13.0 0.2 11.5 2.5 3.0 3 0 0 3 3 3 0 Coiled-coil region of CCDC155 or KASH APG6_N PF17675.1 KFY02569.1 - 4.9 7.7 13.3 1.1 9.8 6.0 2.5 2 1 0 2 2 2 0 Apg6 coiled-coil region ADIP PF11559.8 KFY02569.1 - 5.6 7.0 13.2 3 7.9 3.6 3.1 2 1 1 3 3 3 0 Afadin- and alpha -actinin-Binding TSC22 PF01166.18 KFY02569.1 - 5.8 7.3 11.0 7 7.0 0.0 4.1 4 0 0 4 4 4 0 TSC-22/dip/bun family Lebercilin PF15619.6 KFY02569.1 - 7.4 6.2 14.7 1.2 8.8 5.6 3.0 2 1 1 3 3 3 0 Ciliary protein causing Leber congenital amaurosis disease Chitin_bind_1 PF00187.19 KFY02571.1 - 4.4e-07 30.2 13.0 1.7e-06 28.4 13.0 2.0 1 0 0 1 1 1 1 Chitin recognition protein Peptidase_S41 PF03572.18 KFY02571.1 - 0.051 13.1 1.1 0.68 9.5 0.1 2.2 2 0 0 2 2 2 0 Peptidase family S41 Glyco_hydro_18 PF00704.28 KFY02572.1 - 5.4e-70 236.6 0.0 6.3e-70 236.4 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 TPR_10 PF13374.6 KFY02573.1 - 2.4e-63 208.4 3.9 1.8e-11 43.5 0.0 7.0 7 0 0 7 7 7 6 Tetratricopeptide repeat TPR_12 PF13424.6 KFY02573.1 - 4.7e-55 183.8 7.8 2.5e-12 46.9 0.0 5.8 1 1 5 6 6 6 6 Tetratricopeptide repeat TPR_8 PF13181.6 KFY02573.1 - 1.7e-09 37.1 0.3 0.42 10.9 0.0 5.1 6 0 0 6 6 4 2 Tetratricopeptide repeat TPR_17 PF13431.6 KFY02573.1 - 5.5e-09 35.8 0.7 0.16 12.4 0.0 6.2 7 0 0 7 7 6 1 Tetratricopeptide repeat TPR_7 PF13176.6 KFY02573.1 - 6.8e-09 35.1 0.8 0.082 13.0 0.0 5.3 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_MalT PF17874.1 KFY02573.1 - 1e-08 35.0 12.5 7.6e-05 22.2 2.6 2.8 1 1 2 3 3 3 3 MalT-like TPR region TPR_1 PF00515.28 KFY02573.1 - 1.5e-07 30.9 0.0 0.27 11.1 0.0 5.2 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_2 PF07719.17 KFY02573.1 - 2.1e-07 30.5 0.0 4.5 7.6 0.0 5.2 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_5 PF12688.7 KFY02573.1 - 0.00061 20.0 5.9 0.1 12.8 0.1 4.1 1 1 5 6 6 6 1 Tetratrico peptide repeat TPR_19 PF14559.6 KFY02573.1 - 0.0011 19.4 4.9 0.6 10.6 0.3 3.6 3 1 0 3 3 3 1 Tetratricopeptide repeat DUF956 PF06115.11 KFY02573.1 - 0.0015 18.2 0.8 1.1 9.0 0.1 3.9 2 2 3 5 5 5 1 Domain of unknown function (DUF956) A2M PF00207.22 KFY02573.1 - 0.0024 17.7 1.9 12 5.8 0.0 4.6 2 2 3 5 5 5 0 Alpha-2-macroglobulin family TPR_16 PF13432.6 KFY02573.1 - 0.01 16.5 1.1 6 7.6 0.0 4.2 2 2 1 3 3 3 0 Tetratricopeptide repeat TPR_4 PF07721.14 KFY02573.1 - 0.013 16.1 0.0 5.2 8.0 0.0 4.6 6 0 0 6 6 4 0 Tetratricopeptide repeat Corona_S2 PF01601.16 KFY02573.1 - 0.016 13.7 16.0 0.049 12.1 2.2 2.9 1 1 2 3 3 3 0 Coronavirus S2 glycoprotein DUF4919 PF16266.5 KFY02573.1 - 0.021 14.8 2.4 1.7 8.5 0.0 3.1 2 1 2 4 4 4 0 Domain of unknown function (DUF4919) FAM184 PF15665.5 KFY02573.1 - 0.04 13.7 7.8 0.029 14.2 4.1 2.2 1 1 1 2 2 2 0 Family with sequence similarity 184, A and B DUF4119 PF13494.6 KFY02573.1 - 0.088 13.0 0.3 34 4.7 0.0 3.5 1 1 1 3 3 3 0 Domain of unknown function, B. Theta Gene description (DUF4119) TPR_20 PF14561.6 KFY02573.1 - 0.1 12.9 5.4 0.47 10.8 0.3 3.4 2 2 0 2 2 2 0 Tetratricopeptide repeat FlaE PF07559.14 KFY02573.1 - 0.43 11.2 3.3 34 5.1 3.3 2.8 1 1 0 1 1 1 0 Flagellar basal body protein FlaE Terminase_2 PF03592.16 KFY02573.1 - 0.56 10.7 5.7 2.4 8.6 0.4 2.3 1 1 1 2 2 2 0 Terminase small subunit Rpn3_C PF08375.11 KFY02573.1 - 0.76 10.3 5.1 5.3 7.5 0.1 3.7 3 1 1 4 4 3 0 Proteasome regulatory subunit C-terminal LpoB PF13036.6 KFY02573.1 - 1.5 8.7 12.9 0.73 9.8 1.5 3.1 2 1 2 4 4 4 0 Peptidoglycan-synthase activator LpoB RPN6_C_helix PF18503.1 KFY02573.1 - 9.5 6.1 7.4 54 3.7 0.0 4.2 4 0 0 4 4 4 0 26S proteasome subunit RPN6 C-terminal helix domain F-box-like PF12937.7 KFY02574.1 - 4e-05 23.4 0.0 9.9e-05 22.2 0.0 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KFY02574.1 - 0.021 14.7 0.0 0.068 13.1 0.0 1.9 1 0 0 1 1 1 0 F-box domain SRF-TF PF00319.18 KFY02575.1 - 2.4e-08 33.3 0.1 3.1e-08 33.0 0.1 1.1 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) CRC_subunit PF08624.10 KFY02582.1 - 1e-51 174.9 0.1 1.5e-51 174.4 0.1 1.2 1 0 0 1 1 1 1 Chromatin remodelling complex Rsc7/Swp82 subunit RNB PF00773.19 KFY02583.1 - 5.8e-99 331.5 0.5 9.6e-99 330.8 0.5 1.4 1 0 0 1 1 1 1 RNB domain Rrp44_S1 PF17215.3 KFY02583.1 - 5.9e-31 106.3 0.8 1.5e-30 105.0 0.8 1.7 1 0 0 1 1 1 1 S1 domain Rrp44_CSD1 PF17216.3 KFY02583.1 - 2.1e-28 98.9 0.1 5.6e-28 97.5 0.1 1.8 1 1 0 1 1 1 1 Rrp44-like cold shock domain OB_Dis3 PF17849.1 KFY02583.1 - 7.6e-21 73.9 0.0 2.4e-20 72.3 0.0 1.9 1 0 0 1 1 1 1 Dis3-like cold-shock domain 2 (CSD2) PIN_4 PF13638.6 KFY02583.1 - 1.1e-09 38.6 0.1 9.5e-09 35.6 0.0 2.6 2 1 0 2 2 2 1 PIN domain CSD2 PF17876.1 KFY02583.1 - 3.6e-09 36.7 1.4 5.9e-06 26.4 0.0 3.5 4 0 0 4 4 4 2 Cold shock domain Dis3l2_C_term PF17877.1 KFY02583.1 - 0.0031 17.8 0.1 0.013 15.8 0.1 2.1 1 0 0 1 1 1 1 DIS3-like exonuclease 2 C terminal TcfC PF16967.5 KFY02583.1 - 0.13 11.8 0.0 2.3 7.8 0.0 2.5 2 0 0 2 2 2 0 E-set like domain HC2 PF07382.11 KFY02584.1 - 0.048 13.7 0.1 0.22 11.6 0.0 2.0 2 0 0 2 2 2 0 Histone H1-like nucleoprotein HC2 cobW PF02492.19 KFY02585.1 - 3.5e-11 43.0 0.0 4.2e-11 42.8 0.0 1.1 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain AAA_23 PF13476.6 KFY02585.1 - 0.0008 20.0 0.0 0.00094 19.7 0.0 1.1 1 0 0 1 1 1 1 AAA domain ResIII PF04851.15 KFY02585.1 - 0.028 14.4 0.0 0.029 14.4 0.0 1.1 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit NACHT PF05729.12 KFY02585.1 - 0.053 13.4 0.0 0.06 13.3 0.0 1.1 1 0 0 1 1 1 0 NACHT domain AAA_29 PF13555.6 KFY02585.1 - 0.087 12.6 0.0 0.15 11.8 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain TMEM51 PF15345.6 KFY02585.1 - 0.091 12.6 0.0 0.11 12.4 0.0 1.1 1 0 0 1 1 1 0 Transmembrane protein 51 TIP49 PF06068.13 KFY02585.1 - 0.11 11.7 0.0 0.12 11.5 0.0 1.1 1 0 0 1 1 1 0 TIP49 P-loop domain IstB_IS21 PF01695.17 KFY02585.1 - 0.16 11.7 0.0 0.19 11.5 0.0 1.2 1 0 0 1 1 1 0 IstB-like ATP binding protein MMR_HSR1 PF01926.23 KFY02585.1 - 0.18 11.9 0.0 0.84 9.7 0.0 1.8 2 0 0 2 2 2 0 50S ribosome-binding GTPase PhoH PF02562.16 KFY02585.1 - 0.18 11.2 0.0 0.25 10.8 0.0 1.2 1 0 0 1 1 1 0 PhoH-like protein Dyp_perox PF04261.12 KFY02587.1 - 5.5e-86 288.5 0.0 6.3e-86 288.3 0.0 1.0 1 0 0 1 1 1 1 Dyp-type peroxidase family Glyco_hydro_61 PF03443.14 KFY02588.1 - 2.7e-66 223.4 0.2 4.7e-66 222.6 0.0 1.5 2 0 0 2 2 2 1 Glycosyl hydrolase family 61 SH3_3 PF08239.11 KFY02589.1 - 0.014 15.7 0.0 0.022 15.0 0.0 1.4 1 0 0 1 1 1 0 Bacterial SH3 domain Amidohydro_1 PF01979.20 KFY02590.1 - 2.9e-59 201.1 0.0 4.2e-59 200.6 0.0 1.3 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 KFY02590.1 - 9.8e-06 25.3 0.4 0.0018 17.8 0.0 2.4 2 0 0 2 2 2 2 Amidohydrolase family A_deaminase PF00962.22 KFY02590.1 - 0.011 15.1 0.0 0.017 14.5 0.0 1.2 1 0 0 1 1 1 0 Adenosine/AMP deaminase Sugar_tr PF00083.24 KFY02591.1 - 6.1e-93 312.1 24.6 7.6e-93 311.8 24.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KFY02591.1 - 1.6e-25 89.8 64.4 1.5e-21 76.8 39.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 KFY02591.1 - 0.00024 19.6 2.9 0.00024 19.6 2.9 2.4 2 1 1 3 3 3 1 Organic Anion Transporter Polypeptide (OATP) family TRI12 PF06609.13 KFY02591.1 - 0.0006 18.4 3.9 0.0006 18.4 3.9 1.8 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) DUF1774 PF08611.10 KFY02591.1 - 8.9 6.7 8.1 0.66 10.3 0.1 3.1 3 0 0 3 3 3 0 Fungal protein of unknown function (DUF1774) PHINT_rpt PF14882.6 KFY02592.1 - 1.8 8.9 6.2 34 4.8 0.1 4.0 4 0 0 4 4 4 0 Phage-integrase repeat unit Meth_synt_2 PF01717.18 KFY02593.1 - 4.7e-153 509.2 0.0 1.2e-147 491.4 0.0 2.9 3 1 0 3 3 3 2 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.12 KFY02593.1 - 2.4e-119 398.5 0.7 1.3e-112 376.3 0.0 3.3 4 0 0 4 4 4 2 Cobalamin-independent synthase, N-terminal domain URO-D PF01208.17 KFY02593.1 - 0.00045 19.5 0.1 0.086 12.0 0.0 2.7 3 0 0 3 3 3 2 Uroporphyrinogen decarboxylase (URO-D) VbhA PF18495.1 KFY02593.1 - 0.037 13.9 0.2 17 5.4 0.0 3.1 3 0 0 3 3 3 0 Antitoxin VbhA SHOCT PF09851.9 KFY02593.1 - 1.1 9.1 7.7 0.15 11.8 0.3 3.0 3 0 0 3 3 3 0 Short C-terminal domain Sugar_tr PF00083.24 KFY02601.1 - 1.3e-31 110.0 24.8 2.2e-31 109.2 24.8 1.4 1 0 0 1 1 1 1 Sugar (and other) transporter Phosphodiest PF01663.22 KFY02601.1 - 4.3e-28 98.9 0.0 8.2e-28 98.0 0.0 1.4 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase MFS_1 PF07690.16 KFY02601.1 - 6.9e-16 58.1 49.4 6e-15 55.0 25.0 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily HD PF01966.22 KFY02601.1 - 7.6e-07 29.4 0.1 1.5e-06 28.5 0.1 1.5 1 0 0 1 1 1 1 HD domain MIOX PF05153.15 KFY02601.1 - 0.038 13.6 0.0 0.062 12.9 0.0 1.2 1 0 0 1 1 1 0 Myo-inositol oxygenase HD_4 PF13328.6 KFY02601.1 - 0.053 13.2 0.0 0.13 12.0 0.0 1.6 1 0 0 1 1 1 0 HD domain EF-hand_12 PF17901.1 KFY02603.1 - 0.027 15.0 0.0 0.054 14.0 0.0 1.5 1 0 0 1 1 1 0 EF-hand fold domain HI0933_like PF03486.14 KFY02603.1 - 0.093 11.4 0.1 0.11 11.1 0.1 1.0 1 0 0 1 1 1 0 HI0933-like protein Cu-oxidase_3 PF07732.15 KFY02604.1 - 5.9e-12 45.7 0.1 5.2e-08 32.9 0.0 2.5 2 1 0 2 2 2 2 Multicopper oxidase Cu-oxidase_2 PF07731.14 KFY02604.1 - 9.8e-10 38.3 0.0 0.0032 17.2 0.0 3.3 2 1 0 2 2 2 2 Multicopper oxidase Cu-oxidase PF00394.22 KFY02604.1 - 0.0001 22.5 0.0 0.00022 21.4 0.0 1.6 1 0 0 1 1 1 1 Multicopper oxidase Cupredoxin_1 PF13473.6 KFY02604.1 - 0.012 15.7 0.0 0.55 10.4 0.0 2.4 2 0 0 2 2 2 0 Cupredoxin-like domain Copper-bind PF00127.20 KFY02604.1 - 0.12 12.8 0.0 0.3 11.6 0.0 1.7 1 0 0 1 1 1 0 Copper binding proteins, plastocyanin/azurin family GCS2 PF04107.13 KFY02605.1 - 0.053 12.9 0.4 0.059 12.7 0.4 1.1 1 0 0 1 1 1 0 Glutamate-cysteine ligase family 2(GCS2) UNC-79 PF14776.6 KFY02605.1 - 0.072 11.8 0.1 0.083 11.6 0.1 1.0 1 0 0 1 1 1 0 Cation-channel complex subunit UNC-79 Mre11_DNA_bind PF04152.14 KFY02605.1 - 0.095 13.0 1.3 0.14 12.5 1.3 1.3 1 0 0 1 1 1 0 Mre11 DNA-binding presumed domain SGL PF08450.12 KFY02606.1 - 5.5e-06 26.1 0.0 1e-05 25.3 0.0 1.4 1 0 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region Abhydrolase_3 PF07859.13 KFY02607.1 - 1.7e-34 119.5 0.1 3.3e-34 118.6 0.1 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 KFY02607.1 - 1.2e-05 24.4 0.0 0.00012 21.1 0.0 2.0 2 0 0 2 2 2 1 Carboxylesterase family Peptidase_S9 PF00326.21 KFY02607.1 - 0.0022 17.5 0.2 0.0042 16.6 0.0 1.5 2 0 0 2 2 2 1 Prolyl oligopeptidase family AXE1 PF05448.12 KFY02607.1 - 0.0059 15.3 0.1 0.01 14.5 0.1 1.3 1 0 0 1 1 1 1 Acetyl xylan esterase (AXE1) Abhydrolase_2 PF02230.16 KFY02607.1 - 0.0083 16.0 0.0 0.013 15.4 0.0 1.2 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase DLH PF01738.18 KFY02607.1 - 0.013 15.1 0.1 0.12 11.9 0.0 2.1 2 0 0 2 2 2 0 Dienelactone hydrolase family DUF2974 PF11187.8 KFY02607.1 - 0.053 13.1 0.0 0.076 12.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Abhydrolase_6 PF12697.7 KFY02607.1 - 0.21 12.2 3.8 0.64 10.6 3.8 1.6 1 1 0 1 1 1 0 Alpha/beta hydrolase family Sortilin-Vps10 PF15902.5 KFY02608.1 - 5.7e-22 78.1 0.7 2.1e-08 33.4 0.0 6.1 5 2 1 6 6 6 5 Sortilin, neurotensin receptor 3, BNR PF02012.20 KFY02608.1 - 1.1e-10 39.8 46.0 0.15 12.2 0.1 10.3 10 0 0 10 10 10 9 BNR/Asp-box repeat BNR_6 PF15899.5 KFY02608.1 - 0.00012 21.9 28.9 0.17 12.0 0.1 9.8 10 0 0 10 10 10 1 BNR-Asp box repeat UCR_UQCRX_QCR9 PF05365.12 KFY02608.1 - 9.5 6.3 10.0 25 4.9 0.0 4.2 5 0 0 5 5 5 0 Ubiquinol-cytochrome C reductase, UQCRX/QCR9 like Glyco_hydro2_C5 PF18565.1 KFY02609.1 - 3.6e-33 113.5 0.2 6.2e-33 112.7 0.2 1.4 1 0 0 1 1 1 1 Glycoside hydrolase family 2 C-terminal domain 5 DUF4982 PF16355.5 KFY02609.1 - 3.6e-24 84.5 0.2 1.1e-23 83.0 0.2 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF4982) Glyco_hydro_2_C PF02836.17 KFY02609.1 - 8e-24 84.3 0.0 2.1e-23 82.9 0.0 1.6 2 1 0 2 2 2 1 Glycosyl hydrolases family 2, TIM barrel domain Glyco_hydro_2_N PF02837.18 KFY02609.1 - 9.3e-16 58.2 0.0 2e-15 57.1 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_2 PF00703.21 KFY02609.1 - 4.9e-13 49.7 0.4 1.1e-12 48.6 0.4 1.6 1 0 0 1 1 1 1 Glycosyl hydrolases family 2 BetaGal_dom4_5 PF13364.6 KFY02609.1 - 0.00091 19.8 0.0 0.0067 17.0 0.0 2.3 2 0 0 2 2 2 1 Beta-galactosidase jelly roll domain Invasin_D3 PF09134.10 KFY02609.1 - 0.96 9.8 9.4 0.16 12.3 1.4 3.2 3 1 0 3 3 3 0 Invasin, domain 3 ADH_N PF08240.12 KFY02613.1 - 1.3e-27 95.8 0.9 2.4e-27 95.0 0.9 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KFY02613.1 - 1.1e-19 70.7 0.2 2e-19 69.9 0.2 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 KFY02613.1 - 5.6e-13 48.9 0.2 4.5e-11 42.6 0.2 2.3 1 1 0 1 1 1 1 Glucose dehydrogenase C-terminus ADH_zinc_N_2 PF13602.6 KFY02613.1 - 0.00055 21.0 0.0 0.0014 19.6 0.0 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase UDPG_MGDP_dh_N PF03721.14 KFY02613.1 - 0.017 14.7 0.0 0.029 14.0 0.0 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain AlaDh_PNT_C PF01262.21 KFY02613.1 - 0.028 13.7 0.3 0.071 12.4 0.3 1.7 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_8 PF13450.6 KFY02613.1 - 0.16 12.2 0.2 0.4 10.9 0.2 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain adh_short PF00106.25 KFY02615.1 - 4.7e-51 173.0 0.0 1.2e-50 171.7 0.1 1.6 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 KFY02615.1 - 7.6e-48 163.1 0.2 9.6e-48 162.8 0.2 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KFY02615.1 - 7.7e-11 42.2 0.3 1.3e-10 41.5 0.3 1.5 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 KFY02615.1 - 1e-05 25.1 0.0 1.7e-05 24.4 0.0 1.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Fungal_trans PF04082.18 KFY02616.1 - 5.4e-11 42.0 0.1 3.6e-10 39.3 0.1 2.3 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KFY02616.1 - 5.2e-07 29.7 6.9 9.5e-07 28.8 6.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RLL PF10036.9 KFY02616.1 - 0.11 12.3 1.4 0.22 11.3 1.4 1.4 1 0 0 1 1 1 0 RNA transcription, translation and transport factor protein CRM1_repeat PF18777.1 KFY02616.1 - 0.16 11.5 0.0 0.31 10.6 0.0 1.5 1 0 0 1 1 1 0 Chromosome region maintenance or exportin repeat 2-Hacid_dh_C PF02826.19 KFY02617.1 - 2.3e-55 186.7 0.0 3.1e-55 186.3 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 KFY02617.1 - 2.1e-21 76.0 0.0 2.6e-21 75.7 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 KFY02617.1 - 0.004 17.3 0.0 0.009 16.2 0.0 1.6 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.17 KFY02617.1 - 0.043 14.4 0.0 0.097 13.3 0.0 1.7 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent FMN_dh PF01070.18 KFY02618.1 - 5.5e-106 354.5 0.0 6.6e-106 354.2 0.0 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.28 KFY02618.1 - 3.1e-20 72.1 0.0 6.3e-20 71.1 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain IMPDH PF00478.25 KFY02618.1 - 1.5e-05 24.2 0.0 0.00055 19.0 0.0 2.4 2 0 0 2 2 2 1 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.17 KFY02618.1 - 9.2e-05 21.7 0.0 0.00016 21.0 0.0 1.3 1 0 0 1 1 1 1 Conserved region in glutamate synthase Ribul_P_3_epim PF00834.19 KFY02618.1 - 0.14 11.5 0.0 0.25 10.7 0.0 1.3 1 0 0 1 1 1 0 Ribulose-phosphate 3 epimerase family NMO PF03060.15 KFY02618.1 - 0.21 11.0 0.5 0.35 10.2 0.5 1.3 1 0 0 1 1 1 0 Nitronate monooxygenase Aldo_ket_red PF00248.21 KFY02619.1 - 3e-44 151.4 0.1 4.6e-42 144.2 0.1 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family RNA_pol_Rpb8 PF03870.15 KFY02627.1 - 1.5e-28 99.7 0.0 1.9e-28 99.4 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb8 PAXNEB PF05625.11 KFY02628.1 - 1.1e-107 360.5 0.0 1.2e-107 360.3 0.0 1.0 1 0 0 1 1 1 1 PAXNEB protein MTBP_C PF14920.6 KFY02628.1 - 0.89 9.3 3.3 5.2 6.7 0.2 2.4 1 1 1 2 2 2 0 MDM2-binding zf-C3HC4_3 PF13920.6 KFY02629.1 - 5.4e-09 35.8 11.5 9.3e-09 35.0 11.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KFY02629.1 - 0.27 11.1 12.0 0.48 10.3 12.0 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 tRNA_int_endo PF01974.17 KFY02630.1 - 4.7e-12 45.8 0.0 1.8e-11 43.9 0.0 1.8 2 0 0 2 2 2 1 tRNA intron endonuclease, catalytic C-terminal domain RNase_PH PF01138.21 KFY02631.1 - 4.2e-26 92.0 0.0 8e-26 91.1 0.0 1.5 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 Anp1 PF03452.14 KFY02632.1 - 4.6e-113 377.0 0.0 6.4e-113 376.5 0.0 1.2 1 0 0 1 1 1 1 Anp1 Sec7 PF01369.20 KFY02633.1 - 6.7e-63 211.7 0.0 1e-62 211.1 0.0 1.3 1 0 0 1 1 1 1 Sec7 domain Sec7_N PF12783.7 KFY02633.1 - 2.6e-19 69.7 0.0 2.2e-18 66.7 0.0 2.5 2 0 0 2 2 2 1 Guanine nucleotide exchange factor in Golgi transport N-terminal Abhydrolase_6 PF12697.7 KFY02634.1 - 1.1e-13 52.3 5.7 1.4e-13 52.0 5.7 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_8 PF06259.12 KFY02634.1 - 0.063 12.9 0.1 0.17 11.5 0.1 1.6 1 1 0 1 1 1 0 Alpha/beta hydrolase DsbC_N PF10411.9 KFY02634.1 - 0.17 11.3 0.0 0.41 10.1 0.0 1.5 1 0 0 1 1 1 0 Disulfide bond isomerase protein N-terminus FAD_binding_2 PF00890.24 KFY02635.1 - 2.2e-90 303.8 0.0 2.5e-90 303.6 0.0 1.0 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 KFY02635.1 - 1.9e-07 31.2 0.4 9.3e-07 29.0 0.1 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KFY02635.1 - 3.6e-05 23.5 0.1 0.00014 21.6 0.0 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 KFY02635.1 - 4.6e-05 22.8 0.0 7.6e-05 22.1 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.17 KFY02635.1 - 6.5e-05 22.3 0.1 0.00052 19.3 0.1 2.3 3 0 0 3 3 3 1 Thi4 family FAD_oxidored PF12831.7 KFY02635.1 - 6.7e-05 22.4 0.0 0.00011 21.7 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase GIDA PF01134.22 KFY02635.1 - 0.00017 20.8 2.1 0.00026 20.2 0.0 2.0 2 0 0 2 2 2 1 Glucose inhibited division protein A Pyr_redox_2 PF07992.14 KFY02635.1 - 0.0002 20.7 0.1 0.005 16.1 0.0 2.6 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KFY02635.1 - 0.00044 19.1 0.9 0.0036 16.1 0.1 2.4 2 0 0 2 2 2 1 HI0933-like protein NAD_binding_9 PF13454.6 KFY02635.1 - 0.0047 16.9 0.0 0.0089 16.0 0.0 1.4 1 0 0 1 1 1 1 FAD-NAD(P)-binding Pyr_redox_3 PF13738.6 KFY02635.1 - 0.041 13.1 0.1 0.1 11.9 0.0 1.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KFY02635.1 - 0.19 10.7 0.1 0.33 9.9 0.1 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein TPR_14 PF13428.6 KFY02636.1 - 1.3e-13 50.5 9.6 0.52 11.3 0.1 10.3 9 1 1 10 10 10 2 Tetratricopeptide repeat Mad3_BUB1_I PF08311.12 KFY02636.1 - 1e-07 32.0 9.3 0.19 11.7 0.1 6.8 7 0 0 7 7 7 3 Mad3/BUB1 homology region 1 TPR_8 PF13181.6 KFY02636.1 - 1.4e-07 31.1 2.9 0.23 11.8 0.0 6.5 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_15 PF13429.6 KFY02636.1 - 2.6e-07 30.2 1.2 0.00011 21.5 0.2 3.3 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 KFY02636.1 - 1.8e-06 28.1 2.9 2.6 8.4 0.0 6.9 7 0 0 7 7 7 1 Tetratricopeptide repeat Suf PF05843.14 KFY02636.1 - 1.8e-06 28.1 4.7 0.45 10.5 0.1 4.9 4 2 1 5 5 5 2 Suppressor of forked protein (Suf) TPR_2 PF07719.17 KFY02636.1 - 0.00012 22.0 12.0 1.2 9.4 0.1 6.5 8 0 0 8 8 6 2 Tetratricopeptide repeat TPR_19 PF14559.6 KFY02636.1 - 0.00057 20.4 0.4 1.9 9.1 0.0 5.1 5 1 0 5 5 4 1 Tetratricopeptide repeat SNAP PF14938.6 KFY02636.1 - 0.00076 19.0 0.6 4.1 6.7 0.0 4.5 5 1 1 6 6 6 1 Soluble NSF attachment protein, SNAP RPN7 PF10602.9 KFY02636.1 - 0.0034 17.1 0.0 0.41 10.3 0.0 3.5 3 1 0 3 3 3 1 26S proteasome subunit RPN7 TPR_10 PF13374.6 KFY02636.1 - 0.0037 17.1 9.7 7.8 6.5 0.0 6.9 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_17 PF13431.6 KFY02636.1 - 0.036 14.5 1.5 6.6 7.4 0.0 5.0 6 0 0 6 6 5 0 Tetratricopeptide repeat NRDE-2 PF08424.10 KFY02636.1 - 0.036 13.2 10.1 0.52 9.4 0.2 5.1 3 2 2 6 6 6 0 NRDE-2, necessary for RNA interference TPR_6 PF13174.6 KFY02636.1 - 0.17 12.6 2.4 16 6.4 0.0 5.1 7 0 0 7 7 6 0 Tetratricopeptide repeat ATP-synt_D PF01813.17 KFY02637.1 - 3.6e-71 239.1 1.4 4.4e-71 238.8 1.4 1.1 1 0 0 1 1 1 1 ATP synthase subunit D SYCE1 PF15233.6 KFY02637.1 - 0.022 14.8 1.1 0.53 10.3 0.1 2.3 2 0 0 2 2 2 0 Synaptonemal complex central element protein 1 HtrL_YibB PF09612.10 KFY02637.1 - 0.029 13.9 0.2 0.046 13.2 0.2 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (HtrL_YibB) CobA_CobO_BtuR PF02572.15 KFY02637.1 - 0.17 12.1 3.1 0.85 9.9 0.1 2.4 2 1 1 3 3 3 0 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP RRM_1 PF00076.22 KFY02638.1 - 1.8e-25 88.5 1.0 2.6e-13 49.6 0.3 2.7 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KFY02638.1 - 1.5e-05 24.6 0.0 0.00045 19.8 0.0 2.2 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF4523 PF15023.6 KFY02638.1 - 0.004 17.0 0.0 0.0076 16.1 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF4523) PHM7_cyt PF14703.6 KFY02638.1 - 0.083 13.1 0.4 0.083 13.1 0.4 3.1 2 2 2 4 4 4 0 Cytosolic domain of 10TM putative phosphate transporter Syja_N PF02383.18 KFY02639.1 - 1.7e-71 241.2 0.0 3.6e-70 236.8 0.0 2.3 1 1 0 1 1 1 1 SacI homology domain Tti2 PF10521.9 KFY02640.1 - 5.5e-80 268.9 0.7 1e-79 268.0 0.3 1.6 2 0 0 2 2 2 1 Tti2 family DNA_ligase_A_N PF04675.14 KFY02640.1 - 0.063 13.6 0.1 5.2 7.4 0.0 2.4 2 0 0 2 2 2 0 DNA ligase N terminus PolyA_pol PF01743.20 KFY02641.1 - 6e-26 91.3 0.1 1.3e-25 90.3 0.1 1.6 1 0 0 1 1 1 1 Poly A polymerase head domain PolyA_pol_RNAbd PF12627.7 KFY02641.1 - 6.5e-06 25.8 0.0 1.5e-05 24.6 0.0 1.6 1 0 0 1 1 1 1 Probable RNA and SrmB- binding site of polymerase A TRAPPC-Trs85 PF12739.7 KFY02642.1 - 7.4e-114 380.9 0.0 1e-113 380.4 0.0 1.2 1 0 0 1 1 1 1 ER-Golgi trafficking TRAPP I complex 85 kDa subunit Snf7 PF03357.21 KFY02643.1 - 7.1e-19 68.1 13.1 1.5e-18 67.0 12.8 1.6 1 1 1 2 2 2 1 Snf7 CK2S PF15011.6 KFY02643.1 - 0.015 15.2 5.6 1.2 9.0 2.0 2.7 1 1 0 2 2 2 0 Casein Kinase 2 substrate Baculo_PEP_C PF04513.12 KFY02643.1 - 0.086 12.9 2.2 5.2 7.1 0.4 2.6 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus GOLD_2 PF13897.6 KFY02643.1 - 0.75 10.3 2.9 2.2 8.8 2.9 1.8 1 0 0 1 1 1 0 Golgi-dynamics membrane-trafficking DUF948 PF06103.11 KFY02643.1 - 1.2 9.4 11.0 12 6.3 0.3 3.6 3 1 0 3 3 3 0 Bacterial protein of unknown function (DUF948) BCAS2 PF05700.11 KFY02643.1 - 1.6 8.4 9.8 0.65 9.7 5.4 2.4 2 1 0 2 2 2 0 Breast carcinoma amplified sequence 2 (BCAS2) CorA PF01544.18 KFY02643.1 - 7.2 5.8 7.2 1.1 8.5 2.1 2.1 1 1 1 3 3 3 0 CorA-like Mg2+ transporter protein RNase_H2_suC PF08615.11 KFY02644.1 - 2.6e-24 86.0 0.0 4.4e-24 85.2 0.0 1.4 1 0 0 1 1 1 1 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) zf-C3HC4_2 PF13923.6 KFY02644.1 - 4.5e-09 36.0 12.6 4.5e-09 36.0 12.6 2.7 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KFY02644.1 - 1.9e-07 30.8 13.4 8.9e-07 28.7 10.1 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KFY02644.1 - 6.2e-07 29.2 12.5 6.2e-07 29.2 12.5 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KFY02644.1 - 4e-06 26.7 15.0 6e-06 26.1 12.1 2.3 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 KFY02644.1 - 4.1e-06 26.7 11.9 4.1e-06 26.7 11.9 2.5 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_6 PF14835.6 KFY02644.1 - 8.4e-06 25.6 3.9 8.4e-06 25.6 3.9 1.9 2 0 0 2 2 2 1 zf-RING of BARD1-type protein zf-C3HC4_4 PF15227.6 KFY02644.1 - 8.6e-06 25.8 15.0 2.1e-05 24.6 11.9 2.5 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING U-box PF04564.15 KFY02644.1 - 1e-05 25.6 0.0 2.3e-05 24.4 0.0 1.6 1 0 0 1 1 1 1 U-box domain Prok-RING_4 PF14447.6 KFY02644.1 - 2.8e-05 23.9 12.2 0.0021 17.9 10.2 2.4 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 SAP PF02037.27 KFY02644.1 - 5.8e-05 22.7 0.0 0.00012 21.7 0.0 1.6 1 0 0 1 1 1 1 SAP domain zf-RING_2 PF13639.6 KFY02644.1 - 6.9e-05 23.1 12.1 6.9e-05 23.1 12.1 2.5 2 0 0 2 2 2 1 Ring finger domain zf-RING_10 PF16685.5 KFY02644.1 - 0.00066 19.8 5.2 0.0015 18.6 5.2 1.6 1 0 0 1 1 1 1 zinc RING finger of MSL2 zf-rbx1 PF12678.7 KFY02644.1 - 0.0019 18.4 6.7 0.0019 18.4 6.7 2.4 2 0 0 2 2 2 1 RING-H2 zinc finger domain zf-RING_4 PF14570.6 KFY02644.1 - 0.083 12.7 13.2 0.03 14.1 9.0 2.3 2 1 0 2 2 2 0 RING/Ubox like zinc-binding domain Mob_synth_C PF06463.13 KFY02644.1 - 0.84 9.6 3.4 2.2 8.2 3.4 1.7 1 0 0 1 1 1 0 Molybdenum Cofactor Synthesis C RNase_T PF00929.24 KFY02645.1 - 1.3e-18 68.1 0.0 2e-18 67.5 0.0 1.3 1 0 0 1 1 1 1 Exonuclease DNA_pol_A_exo1 PF01612.20 KFY02645.1 - 2e-05 24.4 0.0 6e-05 22.8 0.0 1.8 1 1 0 1 1 1 1 3'-5' exonuclease MOZ_SAS PF01853.18 KFY02646.1 - 3e-81 271.4 0.1 4.5e-81 270.8 0.1 1.3 1 0 0 1 1 1 1 MOZ/SAS family zf-MYST PF17772.1 KFY02646.1 - 9.5e-23 79.6 0.6 1.8e-22 78.7 0.6 1.5 1 0 0 1 1 1 1 MYST family zinc finger domain Tudor-knot PF11717.8 KFY02646.1 - 4.6e-18 64.8 0.0 1.2e-17 63.5 0.0 1.8 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain Acetyltransf_7 PF13508.7 KFY02646.1 - 0.00021 21.6 0.0 0.00041 20.7 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KFY02646.1 - 0.031 14.5 0.0 0.074 13.3 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family Glyco_hydro_125 PF06824.11 KFY02647.1 - 5.2e-178 592.2 0.0 6e-178 592.0 0.0 1.0 1 0 0 1 1 1 1 Metal-independent alpha-mannosidase (GH125) CDC27 PF09507.10 KFY02648.1 - 1.3e-79 268.6 14.8 3e-79 267.4 14.8 1.5 1 1 0 1 1 1 1 DNA polymerase subunit Cdc27 MCM PF00493.23 KFY02649.1 - 1.8e-103 344.5 0.3 2.7e-103 343.9 0.3 1.3 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 KFY02649.1 - 1.8e-39 134.5 0.3 3.2e-39 133.6 0.3 1.4 1 0 0 1 1 1 1 MCM OB domain MCM6_C PF18263.1 KFY02649.1 - 1.2e-29 102.7 0.2 2.4e-29 101.7 0.2 1.5 1 0 0 1 1 1 1 MCM6 C-terminal winged-helix domain MCM_lid PF17855.1 KFY02649.1 - 9.7e-25 86.8 0.1 2.6e-24 85.5 0.1 1.8 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 KFY02649.1 - 2.3e-24 86.0 0.3 8.4e-24 84.2 0.3 2.1 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 KFY02649.1 - 6.9e-08 32.1 0.0 7.1e-07 28.8 0.0 2.3 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 KFY02649.1 - 0.00091 19.1 0.0 0.0024 17.7 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 KFY02649.1 - 0.0014 18.3 0.0 0.0029 17.3 0.0 1.5 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA_5 PF07728.14 KFY02649.1 - 0.0067 16.4 0.0 0.02 14.9 0.0 1.9 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Aminotran_1_2 PF00155.21 KFY02650.1 - 2.2e-21 76.4 0.0 2.8e-21 76.1 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.7 KFY02650.1 - 0.0013 17.6 0.0 0.019 13.8 0.0 2.4 2 1 0 2 2 2 1 Alanine-glyoxylate amino-transferase ETC_C1_NDUFA4 PF04800.12 KFY02651.1 - 4.3e-36 123.1 3.1 1e-35 121.8 1.5 1.9 2 0 0 2 2 2 1 ETC complex I subunit conserved region F1F0-ATPsyn_F PF10791.9 KFY02652.1 - 3.2e-42 142.9 0.2 3.8e-42 142.7 0.2 1.1 1 0 0 1 1 1 1 Mitochondrial F1-F0 ATP synthase subunit F of fungi WRW PF10206.9 KFY02652.1 - 0.0016 18.8 0.1 0.0022 18.3 0.1 1.3 1 0 0 1 1 1 1 Mitochondrial F1F0-ATP synthase, subunit f SesA PF17107.5 KFY02660.1 - 5.1e-07 29.9 0.1 6.2e-06 26.4 0.0 2.7 3 0 0 3 3 3 1 N-terminal domain on NACHT_NTPase and P-loop NTPases NACHT PF05729.12 KFY02660.1 - 4e-06 26.9 0.0 8e-06 25.9 0.0 1.5 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.6 KFY02660.1 - 0.0016 18.7 0.0 0.0056 16.9 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA PF00004.29 KFY02660.1 - 0.029 14.8 1.3 4.9 7.6 0.0 3.0 2 1 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) Helo_like_N PF17111.5 KFY02660.1 - 0.039 13.3 0.0 0.091 12.1 0.0 1.5 1 0 0 1 1 1 0 Fungal N-terminal domain of STAND proteins PKcGMP_CC PF16808.5 KFY02660.1 - 0.45 10.4 2.0 4.9 7.1 0.3 2.6 2 0 0 2 2 2 0 Coiled-coil N-terminus of cGMP-dependent protein kinase WD40 PF00400.32 KFY02662.1 - 1.4e-56 187.2 10.2 1.5e-08 35.1 0.0 7.1 7 0 0 7 7 7 6 WD domain, G-beta repeat SesA PF17107.5 KFY02662.1 - 1.1e-34 119.2 0.0 2.8e-34 117.9 0.0 1.8 1 0 0 1 1 1 1 N-terminal domain on NACHT_NTPase and P-loop NTPases NACHT PF05729.12 KFY02662.1 - 5.3e-11 42.7 0.4 1.1e-10 41.7 0.4 1.5 1 0 0 1 1 1 1 NACHT domain ANAPC4_WD40 PF12894.7 KFY02662.1 - 1.2e-10 41.6 1.4 0.56 10.6 0.0 5.9 1 1 5 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain VMR2 PF17055.5 KFY02662.1 - 3.2e-05 23.8 0.0 0.24 11.1 0.0 3.4 1 1 2 3 3 3 2 Viral matrix protein M2 WD40_like PF17005.5 KFY02662.1 - 0.00037 19.9 0.0 0.21 10.9 0.0 3.7 2 2 2 4 4 4 1 WD40-like domain CobA_CobO_BtuR PF02572.15 KFY02662.1 - 0.0009 19.5 0.0 0.0019 18.5 0.0 1.5 1 0 0 1 1 1 1 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP PD40 PF07676.12 KFY02662.1 - 0.13 12.2 0.3 71 3.5 0.0 4.0 5 0 0 5 5 5 0 WD40-like Beta Propeller Repeat Zn_clus PF00172.18 KFY02668.1 - 1.8 8.8 15.4 2.6 8.3 15.4 1.2 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain adh_short PF00106.25 KFY02669.1 - 3.9e-39 134.1 0.3 5e-39 133.8 0.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KFY02669.1 - 2e-30 106.1 0.0 2.7e-30 105.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KFY02669.1 - 2.9e-08 33.8 0.1 4.6e-08 33.2 0.1 1.3 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.10 KFY02669.1 - 5.2e-05 22.8 0.0 0.00057 19.4 0.0 2.0 1 1 0 1 1 1 1 Fungal family of unknown function (DUF1776) NAD_binding_10 PF13460.6 KFY02669.1 - 0.00015 21.7 0.0 0.00029 20.8 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KFY02669.1 - 0.00052 19.6 0.0 0.0032 17.0 0.0 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 KFY02669.1 - 0.047 12.8 0.0 0.074 12.1 0.0 1.3 1 0 0 1 1 1 0 RmlD substrate binding domain NmrA PF05368.13 KFY02669.1 - 0.051 13.1 0.0 0.081 12.5 0.0 1.3 1 0 0 1 1 1 0 NmrA-like family UPF0728 PF15092.6 KFY02669.1 - 0.12 12.2 0.0 0.23 11.3 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised protein family UPF0728 MFS_1 PF07690.16 KFY02670.1 - 1.3e-23 83.5 26.8 1.7e-23 83.2 26.8 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KFY02670.1 - 1e-07 31.2 33.6 7.9e-06 25.0 33.6 3.0 1 1 0 1 1 1 1 Sugar (and other) transporter DUF5336 PF17270.2 KFY02670.1 - 0.03 14.0 3.4 5.7 6.5 0.1 3.5 3 0 0 3 3 3 0 Family of unknown function (DUF5336) OATP PF03137.20 KFY02670.1 - 0.22 9.7 12.3 0.26 9.5 1.2 3.0 2 1 1 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family RRM_1 PF00076.22 KFY02671.1 - 6.1e-19 67.6 0.1 1.3e-18 66.6 0.1 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Myb_DNA-binding PF00249.31 KFY02671.1 - 9.3e-05 22.5 0.0 0.00021 21.4 0.0 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 KFY02671.1 - 0.00038 20.3 0.2 0.0014 18.5 0.2 2.0 1 0 0 1 1 1 1 Myb DNA-binding like Myb_DNA-bind_6 PF13921.6 KFY02671.1 - 0.14 12.4 1.0 0.88 9.9 0.2 2.8 3 0 0 3 3 3 0 Myb-like DNA-binding domain zf_C2H2_ZHX PF18387.1 KFY02671.1 - 0.21 11.3 4.5 0.15 11.7 1.2 2.4 2 0 0 2 2 2 0 Zinc-fingers and homeoboxes C2H2 finger domain Glyco_hydro_cc PF11790.8 KFY02673.1 - 3.9e-66 223.0 0.1 3.9e-66 223.0 0.1 1.4 2 0 0 2 2 2 1 Glycosyl hydrolase catalytic core DUF3328 PF11807.8 KFY02674.1 - 5e-29 101.7 2.5 7.2e-29 101.1 2.5 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) DUF4392 PF14336.6 KFY02675.1 - 0.001 18.6 0.0 19 4.6 0.0 3.8 1 1 3 4 4 4 3 Domain of unknown function (DUF4392) EF-hand_5 PF13202.6 KFY02675.1 - 0.027 14.0 0.0 77 3.0 0.0 3.8 4 0 0 4 4 4 0 EF hand Nrap_D3 PF17404.2 KFY02675.1 - 1.3 9.1 5.5 4.3 7.4 0.2 2.1 2 0 0 2 2 2 0 Nrap protein domain 3 Amidoligase_2 PF12224.8 KFY02677.1 - 5e-23 82.1 0.0 7.8e-23 81.4 0.0 1.4 1 0 0 1 1 1 1 Putative amidoligase enzyme Gtr1_RagA PF04670.12 KFY02677.1 - 0.022 14.1 0.0 0.032 13.6 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region MARVEL PF01284.23 KFY02678.1 - 3.9e-07 30.2 15.8 2.4e-05 24.4 15.8 2.1 1 1 0 1 1 1 1 Membrane-associating domain VIT1 PF01988.19 KFY02678.1 - 0.0097 15.8 1.8 0.012 15.5 1.6 1.3 1 1 0 1 1 1 1 VIT family ABC2_membrane_4 PF12730.7 KFY02678.1 - 0.018 15.0 1.6 0.018 15.0 1.6 2.0 1 1 1 2 2 2 0 ABC-2 family transporter protein Tetraspanin PF00335.20 KFY02678.1 - 6.8 6.3 9.8 2.8 7.6 5.6 2.0 1 1 1 2 2 2 0 Tetraspanin family zf-U1 PF06220.12 KFY02679.1 - 0.00033 20.4 0.5 0.00065 19.4 0.5 1.5 1 0 0 1 1 1 1 U1 zinc finger Band_7 PF01145.25 KFY02680.1 - 4.1e-31 108.4 0.4 7.9e-31 107.4 0.4 1.4 1 0 0 1 1 1 1 SPFH domain / Band 7 family Band_7_C PF16200.5 KFY02680.1 - 3.3e-24 84.7 2.4 8.6e-24 83.4 2.4 1.8 1 0 0 1 1 1 1 C-terminal region of band_7 Band_7_1 PF13421.6 KFY02680.1 - 0.0036 17.0 0.0 0.0064 16.2 0.0 1.4 1 0 0 1 1 1 1 SPFH domain-Band 7 family Pox_A11 PF05061.13 KFY02680.1 - 0.12 11.6 1.3 0.27 10.5 1.3 1.6 1 1 0 1 1 1 0 Poxvirus A11 Protein DCB PF16213.5 KFY02681.1 - 3.4e-46 157.1 6.0 7.4e-44 149.5 3.5 3.3 3 0 0 3 3 3 2 Dimerisation and cyclophilin-binding domain of Mon2 Sec7_N PF12783.7 KFY02681.1 - 1.7e-44 151.5 3.5 1.7e-44 151.5 0.8 2.5 2 0 0 2 2 2 1 Guanine nucleotide exchange factor in Golgi transport N-terminal Mon2_C PF16206.5 KFY02681.1 - 1.9e-26 92.5 4.8 7e-22 77.4 2.9 3.1 3 0 0 3 3 3 2 C-terminal region of Mon2 protein DUF1981 PF09324.10 KFY02681.1 - 0.0013 18.5 0.0 0.071 13.0 0.0 3.7 2 0 0 2 2 2 1 Domain of unknown function (DUF1981) DRIM PF07539.12 KFY02681.1 - 0.022 13.1 0.1 0.022 13.1 0.1 3.2 6 0 0 6 6 6 0 Down-regulated in metastasis UQ_con PF00179.26 KFY02682.1 - 3.8e-18 65.5 0.0 3.9e-18 65.4 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 KFY02682.1 - 0.02 15.2 0.0 0.02 15.2 0.0 1.2 1 0 0 1 1 1 0 RWD domain CENP-T_C PF15511.6 KFY02682.1 - 0.18 11.9 0.0 0.24 11.5 0.0 1.2 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T histone fold Complex1_LYR PF05347.15 KFY02683.1 - 2.5e-07 30.6 0.0 2.5e-07 30.6 0.0 2.7 3 0 0 3 3 3 1 Complex 1 protein (LYR family) bZIP_1 PF00170.21 KFY02684.1 - 1.8e-05 24.7 0.8 5.1e-05 23.3 0.8 1.7 1 0 0 1 1 1 1 bZIP transcription factor bZIP_Maf PF03131.17 KFY02684.1 - 1.8 9.1 9.2 0.1 13.1 3.0 2.2 2 0 0 2 2 2 0 bZIP Maf transcription factor Rcd1 PF04078.13 KFY02685.1 - 2.8e-126 420.1 4.7 3.3e-126 419.9 4.7 1.1 1 0 0 1 1 1 1 Cell differentiation family, Rcd1-like 2H-phosphodiest PF08975.10 KFY02685.1 - 0.088 12.8 0.3 0.18 11.8 0.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1868) Pkinase PF00069.25 KFY02686.1 - 7.6e-70 235.3 0.1 1.9e-69 234.0 0.1 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFY02686.1 - 1.3e-38 132.8 0.1 1.1e-37 129.7 0.1 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase KA1 PF02149.19 KFY02686.1 - 9.6e-19 66.9 0.2 1.9e-18 66.0 0.2 1.4 1 0 0 1 1 1 1 Kinase associated domain 1 Kdo PF06293.14 KFY02686.1 - 0.00011 21.6 0.1 0.0002 20.8 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 KFY02686.1 - 0.00013 21.1 0.0 0.00023 20.2 0.0 1.3 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 KFY02686.1 - 0.00014 21.2 0.0 0.0003 20.2 0.0 1.5 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 KFY02686.1 - 0.0033 17.4 0.0 0.018 15.0 0.0 2.0 2 1 1 3 3 3 1 Phosphotransferase enzyme family WaaY PF06176.11 KFY02686.1 - 0.018 14.7 0.1 0.033 13.8 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide core biosynthesis protein (WaaY) YrbL-PhoP_reg PF10707.9 KFY02686.1 - 0.073 12.6 0.0 0.13 11.7 0.0 1.4 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL DUF1604 PF07713.13 KFY02687.1 - 2.2e-39 133.2 3.4 2.7e-39 132.8 0.7 2.7 3 0 0 3 3 3 1 Protein of unknown function (DUF1604) G-patch PF01585.23 KFY02687.1 - 7.7e-07 28.9 1.6 2.2e-06 27.4 1.6 1.8 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.7 KFY02687.1 - 0.29 11.2 5.3 0.13 12.4 0.9 2.8 2 1 1 3 3 3 0 G-patch domain Dioxygenase_C PF00775.21 KFY02692.1 - 1.4e-09 37.6 0.1 2.2e-09 37.0 0.1 1.3 1 0 0 1 1 1 1 Dioxygenase Med2 PF11214.8 KFY02693.1 - 0.0072 16.5 0.2 0.063 13.4 0.0 2.4 2 0 0 2 2 2 1 Mediator complex subunit 2 RRM_1 PF00076.22 KFY02694.1 - 5e-58 192.8 0.0 9.8e-20 70.2 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KFY02694.1 - 1.1e-09 37.9 0.0 0.00024 20.7 0.0 3.4 2 1 1 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KFY02694.1 - 8.6e-08 31.9 0.0 0.021 14.7 0.0 3.6 3 0 0 3 3 3 2 Occluded RNA-recognition motif Nup35_RRM_2 PF14605.6 KFY02694.1 - 2.7e-06 27.3 0.3 0.15 12.1 0.0 3.7 4 0 0 4 4 4 2 Nup53/35/40-type RNA recognition motif RRM_8 PF11835.8 KFY02694.1 - 0.0013 18.9 0.0 0.24 11.6 0.0 2.4 2 0 0 2 2 2 1 RRM-like domain RRM_7 PF16367.5 KFY02694.1 - 0.0037 17.4 0.1 3.4 7.8 0.0 3.3 3 1 0 3 3 3 2 RNA recognition motif Cas_Cas2CT1978 PF09707.10 KFY02694.1 - 0.027 14.5 0.0 4.6 7.4 0.0 2.4 2 0 0 2 2 2 0 CRISPR-associated protein (Cas_Cas2CT1978) Limkain-b1 PF11608.8 KFY02694.1 - 0.14 12.2 0.1 38 4.4 0.1 3.3 3 1 0 3 3 3 0 Limkain b1 PIF1 PF05970.14 KFY02695.1 - 5.8e-58 196.8 0.2 7.9e-45 153.6 0.0 2.2 2 0 0 2 2 2 2 PIF1-like helicase AAA_30 PF13604.6 KFY02695.1 - 1.8e-23 83.3 0.0 4.2e-23 82.1 0.0 1.6 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 KFY02695.1 - 9.9e-12 45.4 0.0 2e-11 44.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 KFY02695.1 - 2.6e-05 24.5 0.0 6.6e-05 23.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain Herpes_Helicase PF02689.14 KFY02695.1 - 0.0001 20.5 0.1 0.00082 17.4 0.0 2.0 2 0 0 2 2 2 1 Helicase AAA_7 PF12775.7 KFY02695.1 - 0.00014 21.5 0.0 0.00028 20.4 0.0 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region UvrD_C_2 PF13538.6 KFY02695.1 - 0.00043 20.0 0.0 0.002 17.9 0.0 2.1 2 0 0 2 2 2 1 UvrD-like helicase C-terminal domain PhoH PF02562.16 KFY02695.1 - 0.001 18.6 0.0 0.0024 17.4 0.0 1.6 1 0 0 1 1 1 1 PhoH-like protein T2SSE PF00437.20 KFY02695.1 - 0.0083 15.2 0.1 0.014 14.5 0.1 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA PF00004.29 KFY02695.1 - 0.014 15.8 0.0 0.033 14.6 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KFY02695.1 - 0.016 15.6 0.1 0.056 13.8 0.1 2.0 1 0 0 1 1 1 0 AAA ATPase domain DUF2075 PF09848.9 KFY02695.1 - 0.023 13.9 0.1 0.049 12.9 0.1 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) SH3_13 PF18335.1 KFY02695.1 - 0.037 13.9 0.1 0.12 12.3 0.1 1.8 1 0 0 1 1 1 0 ATP-dependent RecD-like DNA helicase SH3 domain Viral_helicase1 PF01443.18 KFY02695.1 - 0.04 13.7 0.1 3.7 7.2 0.0 2.6 2 1 0 2 2 2 0 Viral (Superfamily 1) RNA helicase RNA_helicase PF00910.22 KFY02695.1 - 0.042 14.2 0.0 0.14 12.5 0.0 1.9 1 0 0 1 1 1 0 RNA helicase AAA_29 PF13555.6 KFY02695.1 - 0.05 13.4 0.0 0.15 11.8 0.0 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain NB-ARC PF00931.22 KFY02695.1 - 0.07 12.3 0.0 0.12 11.5 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain UvrD-helicase PF00580.21 KFY02695.1 - 0.091 12.3 0.1 0.23 10.9 0.1 1.6 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain Mg_chelatase PF01078.21 KFY02695.1 - 0.094 12.1 0.3 0.31 10.4 0.0 1.9 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI NACHT PF05729.12 KFY02695.1 - 0.11 12.4 0.0 0.23 11.4 0.0 1.5 1 0 0 1 1 1 0 NACHT domain ABC_tran PF00005.27 KFY02695.1 - 0.14 12.7 0.0 0.41 11.2 0.0 1.7 1 0 0 1 1 1 0 ABC transporter TrwB_AAD_bind PF10412.9 KFY02695.1 - 0.15 10.9 0.0 0.29 10.0 0.0 1.3 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain Mitofilin PF09731.9 KFY02695.1 - 0.19 10.5 3.3 0.31 9.8 3.3 1.2 1 0 0 1 1 1 0 Mitochondrial inner membrane protein p450 PF00067.22 KFY02696.1 - 6.1e-62 209.9 0.0 7.9e-62 209.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 E1-E2_ATPase PF00122.20 KFY02697.1 - 7.7e-49 165.7 0.2 2.6e-48 163.9 0.0 2.0 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.26 KFY02697.1 - 3.6e-34 118.9 0.0 5.9e-34 118.2 0.0 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HMA PF00403.26 KFY02697.1 - 3.3e-28 97.9 5.7 4.2e-10 39.9 0.1 4.6 4 0 0 4 4 4 4 Heavy-metal-associated domain Hydrolase_3 PF08282.12 KFY02697.1 - 0.00032 20.5 0.1 0.00054 19.8 0.1 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Poly_export PF02563.16 KFY02697.1 - 0.0034 17.6 0.0 2.7 8.3 0.0 2.5 2 0 0 2 2 2 2 Polysaccharide biosynthesis/export protein HAD PF12710.7 KFY02697.1 - 0.035 14.5 0.0 0.72 10.2 0.0 2.9 2 1 0 2 2 2 0 haloacid dehalogenase-like hydrolase DUF3795 PF12675.7 KFY02697.1 - 0.41 11.1 3.0 11 6.5 0.1 3.1 4 0 0 4 4 4 0 Protein of unknown function (DUF3795) NPC1_N PF16414.5 KFY02698.1 - 1.5e-84 283.4 7.4 2.1e-84 282.9 7.4 1.2 1 0 0 1 1 1 1 Niemann-Pick C1 N terminus Patched PF02460.18 KFY02698.1 - 1.6e-72 244.9 13.7 1.4e-71 241.7 13.7 1.9 1 1 0 1 1 1 1 Patched family Sterol-sensing PF12349.8 KFY02698.1 - 3.7e-53 179.5 6.6 3.7e-53 179.5 6.6 3.0 2 1 0 2 2 2 1 Sterol-sensing domain of SREBP cleavage-activation MMPL PF03176.15 KFY02698.1 - 3e-05 23.1 6.9 3e-05 23.1 6.9 3.0 2 1 0 2 2 2 1 MMPL family Folate_rec PF03024.14 KFY02698.1 - 0.00034 20.5 2.0 0.00066 19.6 2.0 1.4 1 0 0 1 1 1 1 Folate receptor family DUF1256 PF06866.11 KFY02701.1 - 0.23 10.9 0.0 0.23 10.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1256) Complex1_30kDa PF00329.19 KFY02702.1 - 4.9e-47 159.6 0.0 6.8e-47 159.1 0.0 1.2 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 30 Kd subunit zf-RING_4 PF14570.6 KFY02703.1 - 7.8e-20 70.4 12.1 1.3e-19 69.7 12.1 1.4 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-C3HC4_3 PF13920.6 KFY02703.1 - 8.4e-08 32.0 6.9 1.7e-07 31.0 6.9 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) RRM_1 PF00076.22 KFY02703.1 - 7e-07 29.0 0.0 3.8e-06 26.6 0.0 2.3 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Rtf2 PF04641.12 KFY02703.1 - 0.00014 21.4 2.5 0.00014 21.4 2.5 3.2 2 1 0 2 2 1 1 Rtf2 RING-finger zf-RING_2 PF13639.6 KFY02703.1 - 0.00041 20.6 9.8 0.00076 19.8 9.8 1.5 1 0 0 1 1 1 1 Ring finger domain Prok-RING_4 PF14447.6 KFY02703.1 - 0.0039 17.0 8.7 0.11 12.4 9.4 2.2 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 Baculo_IE-1 PF05290.11 KFY02703.1 - 0.028 14.3 4.2 0.056 13.4 4.2 1.4 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) Nup35_RRM_2 PF14605.6 KFY02703.1 - 0.043 13.8 0.0 0.086 12.9 0.0 1.4 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif SET_assoc PF11767.8 KFY02703.1 - 0.084 12.5 0.0 0.17 11.6 0.0 1.4 1 0 0 1 1 1 0 Histone lysine methyltransferase SET associated FYVE PF01363.21 KFY02703.1 - 0.12 12.5 3.7 0.25 11.5 3.7 1.5 1 0 0 1 1 1 0 FYVE zinc finger zf-C3HC4 PF00097.25 KFY02703.1 - 0.14 12.1 9.9 0.27 11.2 9.9 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KFY02703.1 - 0.29 11.1 10.2 0.5 10.4 10.2 1.4 1 0 0 1 1 1 0 zinc-RING finger domain zf-UDP PF14569.6 KFY02703.1 - 0.34 11.1 4.3 0.83 9.8 4.3 1.6 1 0 0 1 1 1 0 Zinc-binding RING-finger zf-C3HC4_2 PF13923.6 KFY02703.1 - 1.8 8.4 9.9 3.2 7.7 9.9 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DUF4288 PF14119.6 KFY02703.1 - 6.5 7.2 5.5 4.7 7.7 2.7 2.2 2 0 0 2 2 1 0 Domain of unknown function (DUF4288) PNP_UDP_1 PF01048.20 KFY02704.1 - 2.9e-41 141.2 0.3 3.5e-41 141.0 0.3 1.1 1 0 0 1 1 1 1 Phosphorylase superfamily Med13_C PF06333.12 KFY02705.1 - 1.6e-28 100.0 0.6 1.7e-28 99.8 0.6 1.0 1 0 0 1 1 1 1 Mediator complex subunit 13 C-terminal domain T-box_assoc PF16176.5 KFY02705.1 - 0.042 13.9 0.1 0.05 13.7 0.1 1.3 1 0 0 1 1 1 0 T-box transcription factor-associated Cpn60_TCP1 PF00118.24 KFY02707.1 - 4e-21 75.2 0.1 5.4e-21 74.8 0.1 1.1 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family FYVE PF01363.21 KFY02707.1 - 1.6e-12 47.4 9.8 2.8e-12 46.6 9.8 1.4 1 0 0 1 1 1 1 FYVE zinc finger FYVE_2 PF02318.16 KFY02707.1 - 0.31 11.3 5.5 0.73 10.1 5.5 1.5 1 0 0 1 1 1 0 FYVE-type zinc finger Mpv17_PMP22 PF04117.12 KFY02708.1 - 1.2e-21 76.7 2.9 2e-21 75.9 2.9 1.4 1 0 0 1 1 1 1 Mpv17 / PMP22 family TPP1 PF10341.9 KFY02708.1 - 0.00013 21.9 0.0 0.00029 20.8 0.0 1.6 1 0 0 1 1 1 1 Shelterin complex subunit, TPP1/ACD IF4E PF01652.18 KFY02709.1 - 6.2e-54 182.1 0.2 7.7e-54 181.8 0.2 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E AMP-binding PF00501.28 KFY02710.1 - 7.9e-69 232.3 0.0 1.1e-68 231.9 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KFY02710.1 - 1.4e-15 58.1 0.1 2.8e-15 57.0 0.1 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain BolA PF01722.18 KFY02711.1 - 1.2e-30 105.5 2.3 1.5e-30 105.3 2.3 1.1 1 0 0 1 1 1 1 BolA-like protein NTP_transf_6 PF06042.11 KFY02711.1 - 0.041 13.8 0.1 0.046 13.6 0.1 1.2 1 0 0 1 1 1 0 Nucleotidyltransferase Translin PF01997.16 KFY02712.1 - 6.8e-60 202.6 0.0 8.3e-60 202.3 0.0 1.0 1 0 0 1 1 1 1 Translin family Mannosyl_trans PF05007.13 KFY02713.1 - 2.1e-75 254.0 14.9 3.4e-75 253.3 14.9 1.3 1 0 0 1 1 1 1 Mannosyltransferase (PIG-M) PIG-U PF06728.13 KFY02713.1 - 6.3e-09 35.4 20.7 1.4e-08 34.2 20.7 1.5 1 1 0 1 1 1 1 GPI transamidase subunit PIG-U GT87 PF09594.10 KFY02713.1 - 9.5e-05 22.2 18.4 9.5e-05 22.2 18.4 2.6 1 1 2 3 3 3 1 Glycosyltransferase family 87 HPD PF05044.12 KFY02713.1 - 0.052 13.4 0.3 0.088 12.7 0.3 1.3 1 0 0 1 1 1 0 Homeo-prospero domain ABC_membrane PF00664.23 KFY02729.1 - 9e-110 366.6 38.1 8.6e-56 189.6 13.7 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 KFY02729.1 - 4.2e-66 221.6 0.3 2.3e-31 109.1 0.0 3.2 3 0 0 3 3 3 2 ABC transporter SMC_N PF02463.19 KFY02729.1 - 1.2e-12 47.8 0.0 0.00034 20.1 0.0 3.7 2 2 1 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 KFY02729.1 - 1.5e-06 27.8 1.2 0.0079 15.9 0.2 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.6 KFY02729.1 - 1.8e-06 28.4 2.6 0.006 17.0 0.1 3.2 2 2 1 3 3 2 2 AAA ATPase domain RsgA_GTPase PF03193.16 KFY02729.1 - 3.7e-06 27.0 0.0 0.24 11.3 0.0 3.6 3 0 0 3 3 3 2 RsgA GTPase AAA_25 PF13481.6 KFY02729.1 - 9.9e-05 22.0 0.8 0.15 11.7 0.0 3.4 3 0 0 3 3 3 1 AAA domain AAA_22 PF13401.6 KFY02729.1 - 0.00013 22.2 0.7 0.6 10.4 0.0 3.9 3 1 0 3 3 3 1 AAA domain AAA_15 PF13175.6 KFY02729.1 - 0.00015 21.6 0.0 0.94 9.1 0.0 3.0 2 1 1 3 3 3 2 AAA ATPase domain ABC_ATPase PF09818.9 KFY02729.1 - 0.00065 18.6 1.9 0.12 11.1 0.0 2.7 3 0 0 3 3 3 2 Predicted ATPase of the ABC class AAA PF00004.29 KFY02729.1 - 0.0018 18.7 1.2 24 5.3 0.1 4.1 4 0 0 4 4 4 0 ATPase family associated with various cellular activities (AAA) G-alpha PF00503.20 KFY02729.1 - 0.0022 17.2 0.0 1.5 7.9 0.0 2.4 2 0 0 2 2 2 2 G-protein alpha subunit AAA_21 PF13304.6 KFY02729.1 - 0.0024 17.7 1.6 6.3 6.5 0.0 3.7 3 1 0 4 4 4 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_28 PF13521.6 KFY02729.1 - 0.0027 18.0 0.2 0.51 10.6 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 KFY02729.1 - 0.003 17.3 3.1 2.3 7.9 0.0 3.8 4 0 0 4 4 4 1 AAA domain AAA_7 PF12775.7 KFY02729.1 - 0.0035 16.9 0.0 2.9 7.3 0.0 2.4 2 0 0 2 2 2 2 P-loop containing dynein motor region DUF87 PF01935.17 KFY02729.1 - 0.0067 16.5 1.3 2 8.5 0.0 2.7 3 0 0 3 3 2 1 Helicase HerA, central domain SbcCD_C PF13558.6 KFY02729.1 - 0.0074 16.5 3.2 4.5 7.6 0.4 3.7 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit Zeta_toxin PF06414.12 KFY02729.1 - 0.0098 15.2 1.4 5.9 6.1 0.0 3.4 3 0 0 3 3 3 1 Zeta toxin PRK PF00485.18 KFY02729.1 - 0.011 15.5 0.3 2.4 7.8 0.0 3.3 3 0 0 3 3 3 0 Phosphoribulokinase / Uridine kinase family AAA_5 PF07728.14 KFY02729.1 - 0.012 15.6 0.1 11 6.0 0.0 3.2 3 0 0 3 3 2 0 AAA domain (dynein-related subfamily) AAA_33 PF13671.6 KFY02729.1 - 0.03 14.5 0.2 14 5.9 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 KFY02729.1 - 0.039 13.7 0.1 8.3 6.1 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 KFY02729.1 - 0.069 13.7 2.0 15 6.1 0.0 3.3 2 1 1 3 3 3 0 AAA domain DUF815 PF05673.13 KFY02729.1 - 0.069 12.3 0.1 5.1 6.2 0.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF815) Rad17 PF03215.15 KFY02729.1 - 0.16 11.9 0.1 0.76 9.7 0.0 2.0 2 0 0 2 2 2 0 Rad17 P-loop domain RNA_helicase PF00910.22 KFY02729.1 - 0.16 12.3 0.0 21 5.5 0.0 3.0 2 0 0 2 2 2 0 RNA helicase AAA_23 PF13476.6 KFY02729.1 - 0.49 10.9 2.7 12 6.4 0.0 2.9 3 0 0 3 3 2 0 AAA domain MMR_HSR1 PF01926.23 KFY02729.1 - 5.4 7.1 6.7 14 5.8 0.0 3.4 3 0 0 3 3 3 0 50S ribosome-binding GTPase Skp1 PF01466.19 KFY02730.1 - 1.4e-28 98.8 0.2 2.1e-28 98.1 0.2 1.3 1 0 0 1 1 1 1 Skp1 family, dimerisation domain Skp1_POZ PF03931.15 KFY02730.1 - 9.4e-21 73.8 0.2 2.3e-20 72.5 0.1 1.7 2 0 0 2 2 2 1 Skp1 family, tetramerisation domain Myb_DNA-binding PF00249.31 KFY02732.1 - 6.8e-16 58.2 2.7 3e-09 36.9 0.6 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KFY02732.1 - 2.9e-09 37.1 0.7 4.5e-05 23.6 0.1 2.6 1 1 1 2 2 2 2 Myb-like DNA-binding domain TFIIA PF03153.13 KFY02732.1 - 0.016 15.2 19.0 0.024 14.7 19.0 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Glyco_hydro_16 PF00722.21 KFY02733.1 - 7.7e-46 155.8 3.5 1.1e-45 155.3 3.5 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Chitin_bind_1 PF00187.19 KFY02733.1 - 0.033 14.6 12.5 0.07 13.6 12.5 1.5 1 0 0 1 1 1 0 Chitin recognition protein WD40 PF00400.32 KFY02734.1 - 6.2e-41 137.6 19.3 1.6e-06 28.7 0.2 7.7 7 0 0 7 7 7 7 WD domain, G-beta repeat F-box-like PF12937.7 KFY02734.1 - 1.4e-10 40.9 0.1 3.5e-10 39.6 0.1 1.7 1 0 0 1 1 1 1 F-box-like ANAPC4_WD40 PF12894.7 KFY02734.1 - 7.3e-09 35.8 0.3 1.4 9.3 0.0 5.7 2 2 4 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain F-box PF00646.33 KFY02734.1 - 1.9e-08 34.0 0.4 5.8e-08 32.4 0.1 2.0 2 0 0 2 2 2 1 F-box domain Nup160 PF11715.8 KFY02734.1 - 4e-05 22.5 2.8 2.5 6.7 0.0 5.0 3 1 2 5 5 5 2 Nucleoporin Nup120/160 BBS2_Mid PF14783.6 KFY02734.1 - 0.00054 20.0 0.1 1.4 8.9 0.0 4.5 4 1 1 5 5 5 1 Ciliary BBSome complex subunit 2, middle region WD40_like PF17005.5 KFY02734.1 - 0.056 12.8 0.1 2.4 7.4 0.0 2.3 2 0 0 2 2 2 0 WD40-like domain PQQ_2 PF13360.6 KFY02734.1 - 0.078 12.5 1.4 4.3 6.8 1.1 2.7 1 1 1 2 2 2 0 PQQ-like domain F-box_4 PF15966.5 KFY02734.1 - 0.098 12.5 0.1 0.3 11.0 0.0 1.9 2 0 0 2 2 2 0 F-box CDC4_D PF16856.5 KFY02734.1 - 0.15 12.0 0.0 0.39 10.6 0.0 1.7 1 0 0 1 1 1 0 Cell division control protein 4 dimerisation domain Aha1_N PF09229.11 KFY02735.1 - 4.4e-40 137.1 0.1 5.2e-40 136.8 0.1 1.1 1 0 0 1 1 1 1 Activator of Hsp90 ATPase, N-terminal DUF5416 PF17437.2 KFY02735.1 - 0.13 12.1 0.3 0.17 11.6 0.3 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5416) TRAP_alpha PF03896.16 KFY02736.1 - 2.2e-08 33.7 0.5 1.5e-07 30.9 0.1 2.0 2 0 0 2 2 2 1 Translocon-associated protein (TRAP), alpha subunit Pkinase PF00069.25 KFY02737.1 - 8.5e-24 84.3 0.0 1.4e-23 83.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Ank_2 PF12796.7 KFY02737.1 - 1e-15 58.1 0.0 6.6e-09 36.2 0.0 4.6 4 0 0 4 4 4 2 Ankyrin repeats (3 copies) Pkinase_Tyr PF07714.17 KFY02737.1 - 1.9e-15 56.9 0.0 3.3e-15 56.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Ank_3 PF13606.6 KFY02737.1 - 3.3e-09 36.2 1.7 0.0066 16.9 0.0 6.8 7 0 0 7 7 7 1 Ankyrin repeat Ank PF00023.30 KFY02737.1 - 3.1e-08 33.7 1.0 0.00011 22.4 0.0 5.1 6 0 0 6 6 6 1 Ankyrin repeat Ank_4 PF13637.6 KFY02737.1 - 1e-05 26.0 0.6 0.18 12.5 0.1 5.8 4 2 2 6 6 6 2 Ankyrin repeats (many copies) Pkinase_fungal PF17667.1 KFY02737.1 - 0.002 17.0 0.0 0.0034 16.2 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Asp_protease_2 PF13650.6 KFY02737.1 - 0.094 13.4 0.0 0.27 11.9 0.0 1.8 1 0 0 1 1 1 0 Aspartyl protease Imm8 PF15586.6 KFY02737.1 - 0.16 12.0 0.0 0.56 10.3 0.0 1.9 2 0 0 2 2 2 0 Immunity protein 8 HeLo PF14479.6 KFY02738.1 - 5.7e-11 42.6 0.4 1.1e-10 41.7 0.3 1.4 1 1 0 1 1 1 1 Prion-inhibition and propagation GHMP_kinases_N PF00288.26 KFY02739.1 - 4.4e-15 55.7 4.1 9.2e-15 54.6 3.5 1.9 2 0 0 2 2 2 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 KFY02739.1 - 2.4e-05 24.6 0.4 4.7e-05 23.7 0.4 1.4 1 0 0 1 1 1 1 GHMP kinases C terminal Pantoate_ligase PF02569.15 KFY02740.1 - 1.9e-93 312.5 0.0 2.2e-93 312.3 0.0 1.0 1 0 0 1 1 1 1 Pantoate-beta-alanine ligase DEAD PF00270.29 KFY02741.1 - 2.5e-41 141.4 0.1 2.9e-40 137.9 0.1 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KFY02741.1 - 1.7e-21 76.7 0.0 5.6e-21 75.0 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 KFY02741.1 - 1.4e-16 60.5 0.0 2.8e-16 59.5 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.15 KFY02741.1 - 0.00048 20.2 0.0 0.0012 18.9 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 KFY02741.1 - 0.011 15.0 0.0 0.02 14.1 0.0 1.3 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase WD40 PF00400.32 KFY02742.1 - 3.5e-07 30.8 6.7 0.38 11.7 0.0 5.8 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFY02742.1 - 0.037 14.3 0.1 0.33 11.3 0.0 2.5 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain Fungal_trans_2 PF11951.8 KFY02743.1 - 1.4e-11 43.9 1.1 1e-10 41.0 1.1 2.0 1 1 0 1 1 1 1 Fungal specific transcription factor domain DUF846 PF05832.12 KFY02745.1 - 1.3e-50 171.1 13.7 1.5e-50 170.8 13.7 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF846) DUF5504 PF17608.2 KFY02745.1 - 2 8.5 10.4 0.23 11.6 4.2 2.2 1 1 1 2 2 2 0 Family of unknown function (DUF5504) SAM_2 PF07647.17 KFY02746.1 - 2.5e-10 40.3 0.0 7.1e-10 38.8 0.0 1.9 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) bZIP_1 PF00170.21 KFY02746.1 - 2.1e-05 24.5 4.4 6.1e-05 23.0 2.4 2.6 2 0 0 2 2 2 1 bZIP transcription factor SAM_1 PF00536.30 KFY02746.1 - 0.00042 20.7 0.0 0.001 19.5 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) bZIP_2 PF07716.15 KFY02746.1 - 0.0022 18.0 7.2 0.0026 17.8 4.6 2.5 2 0 0 2 2 2 1 Basic region leucine zipper Tugs PF17840.1 KFY02746.1 - 0.11 12.7 0.1 0.41 10.9 0.1 2.0 1 0 0 1 1 1 0 Tethering Ubl4a to BAGS domain zf-C2H2_4 PF13894.6 KFY02746.1 - 9.7 7.3 17.2 6.9 7.8 0.1 5.2 5 0 0 5 5 5 0 C2H2-type zinc finger ATG22 PF11700.8 KFY02748.1 - 4e-187 622.6 12.5 4.7e-187 622.4 12.5 1.0 1 0 0 1 1 1 1 Vacuole effluxer Atg22 like MFS_1 PF07690.16 KFY02748.1 - 0.0026 16.8 9.4 0.0026 16.8 9.4 3.3 2 2 1 3 3 3 3 Major Facilitator Superfamily Pex24p PF06398.11 KFY02748.1 - 0.35 9.8 8.8 1.6 7.6 6.5 2.6 1 1 0 2 2 2 0 Integral peroxisomal membrane peroxin Med14 PF08638.11 KFY02749.1 - 2.9e-64 216.0 0.0 5.7e-64 215.1 0.0 1.5 1 0 0 1 1 1 1 Mediator complex subunit MED14 adh_short PF00106.25 KFY02750.1 - 0.031 13.7 0.0 0.056 12.9 0.0 1.3 1 0 0 1 1 1 0 short chain dehydrogenase PfkB PF00294.24 KFY02751.1 - 3.2e-41 141.6 0.6 4.1e-41 141.2 0.6 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Zn_clus PF00172.18 KFY02752.1 - 1.1e-08 35.0 11.1 2.2e-08 34.1 11.1 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 KFY02752.1 - 4e-06 25.9 1.6 0.00032 19.7 0.0 2.5 2 0 0 2 2 2 2 Fungal specific transcription factor domain HypA PF01155.19 KFY02752.1 - 1.4 9.0 4.0 1.8 8.6 2.4 1.9 2 0 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Sugar_tr PF00083.24 KFY02753.1 - 1.1e-109 367.3 30.6 2e-109 366.5 30.6 1.4 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KFY02753.1 - 3.5e-21 75.5 61.4 2.9e-13 49.5 25.8 3.5 2 1 2 4 4 4 2 Major Facilitator Superfamily Fungal_trans_2 PF11951.8 KFY02753.1 - 1.1e-11 44.2 0.1 2.3e-11 43.1 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain MFS_2 PF13347.6 KFY02753.1 - 7.7e-05 21.4 8.7 7.7e-05 21.4 8.7 3.1 2 2 1 3 3 3 1 MFS/sugar transport protein Methyltransf_11 PF08241.12 KFY02754.1 - 3.4e-13 50.1 0.0 6.9e-13 49.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KFY02754.1 - 6.5e-13 49.2 0.0 1.4e-12 48.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KFY02754.1 - 1.6e-11 44.3 0.0 2.2e-11 43.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KFY02754.1 - 2.9e-11 43.4 0.0 5.3e-11 42.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KFY02754.1 - 1.9e-08 33.9 0.0 2.7e-08 33.5 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 KFY02754.1 - 2.5e-08 34.6 0.0 7.3e-08 33.1 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain TPMT PF05724.11 KFY02754.1 - 0.00029 20.6 0.0 0.00089 19.0 0.0 1.7 2 0 0 2 2 2 1 Thiopurine S-methyltransferase (TPMT) Methyltransf_32 PF13679.6 KFY02754.1 - 0.00044 20.3 0.1 0.0016 18.5 0.0 1.8 1 1 1 2 2 2 1 Methyltransferase domain CMAS PF02353.20 KFY02754.1 - 0.0064 15.8 0.0 0.008 15.5 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase RrnaAD PF00398.20 KFY02754.1 - 0.019 14.1 0.0 0.029 13.5 0.0 1.5 1 1 0 1 1 1 0 Ribosomal RNA adenine dimethylase MTS PF05175.14 KFY02754.1 - 0.046 13.3 0.0 0.18 11.3 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase small domain Fig1 PF12351.8 KFY02755.1 - 1.9e-10 41.0 3.7 1.9e-10 41.0 3.7 1.6 2 0 0 2 2 2 1 Ca2+ regulator and membrane fusion protein Fig1 Claudin_2 PF13903.6 KFY02755.1 - 0.022 14.5 1.2 0.022 14.5 1.2 1.9 2 0 0 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction E1-E2_ATPase PF00122.20 KFY02755.1 - 0.6 9.6 3.5 0.37 10.3 1.3 1.7 2 0 0 2 2 2 0 E1-E2 ATPase GMC_oxred_N PF00732.19 KFY02756.1 - 2.2e-45 155.3 0.5 3.4e-45 154.7 0.5 1.3 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KFY02756.1 - 2.2e-24 86.6 1.8 5e-23 82.2 0.1 2.4 2 0 0 2 2 2 1 GMC oxidoreductase FAD_binding_2 PF00890.24 KFY02756.1 - 3.8e-07 29.6 0.6 9.6e-05 21.6 0.2 2.2 2 0 0 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.14 KFY02756.1 - 2.7e-05 23.5 0.2 0.0013 18.0 0.1 2.8 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KFY02756.1 - 8.6e-05 22.3 0.5 0.27 10.8 0.1 2.4 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 KFY02756.1 - 0.00013 21.3 0.0 0.00019 20.8 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 KFY02756.1 - 0.0015 18.8 0.6 0.0059 16.8 0.6 2.1 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 KFY02756.1 - 0.12 11.6 1.1 0.93 8.7 0.1 2.5 3 0 0 3 3 3 0 Thi4 family FAD_oxidored PF12831.7 KFY02756.1 - 0.12 11.7 0.4 0.18 11.1 0.4 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase ThiF PF00899.21 KFY02756.1 - 0.13 11.6 0.0 0.24 10.7 0.0 1.4 1 0 0 1 1 1 0 ThiF family PQ-loop PF04193.14 KFY02757.1 - 4.2e-22 77.7 8.2 1.4e-13 50.4 2.7 2.5 2 0 0 2 2 2 2 PQ loop repeat DUF5516 PF17637.2 KFY02757.1 - 0.15 11.9 2.0 3.7 7.4 0.0 3.1 3 0 0 3 3 3 0 Family of unknown function (DUF5516) Med8 PF10232.9 KFY02758.1 - 6.2e-27 94.7 0.1 7.9e-27 94.3 0.1 1.2 1 0 0 1 1 1 1 Mediator of RNA polymerase II transcription complex subunit 8 Spt5_N PF11942.8 KFY02758.1 - 0.032 15.2 4.5 0.082 13.9 4.5 1.7 1 0 0 1 1 1 0 Spt5 transcription elongation factor, acidic N-terminal NOA36 PF06524.12 KFY02758.1 - 6.5 6.0 5.2 8.9 5.5 5.2 1.1 1 0 0 1 1 1 0 NOA36 protein CFEM PF05730.11 KFY02761.1 - 8.7e-05 22.5 1.3 0.0004 20.4 1.3 2.2 1 0 0 1 1 1 1 CFEM domain PQ-loop PF04193.14 KFY02762.1 - 0.029 14.2 0.1 0.062 13.1 0.1 1.5 1 0 0 1 1 1 0 PQ loop repeat Sugar_tr PF00083.24 KFY02763.1 - 6.2e-79 266.0 22.2 7.6e-79 265.7 22.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KFY02763.1 - 6.7e-31 107.5 38.9 1.3e-24 86.8 24.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 KFY02763.1 - 3.1e-06 25.9 6.8 0.00011 20.7 4.0 2.1 2 0 0 2 2 2 2 Fungal trichothecene efflux pump (TRI12) DUF5542 PF17696.1 KFY02763.1 - 0.33 11.1 3.8 0.19 11.9 1.7 1.7 2 0 0 2 2 2 0 Family of unknown function (DUF5542) ADH_zinc_N_2 PF13602.6 KFY02764.1 - 5.2e-25 89.0 0.7 1.1e-24 88.0 0.0 1.9 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 KFY02764.1 - 3.4e-15 56.2 0.0 5.9e-15 55.4 0.0 1.5 1 1 0 1 1 1 1 Zinc-binding dehydrogenase NAD_binding_8 PF13450.6 KFY02765.1 - 3.3e-14 52.9 0.0 8.9e-14 51.5 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KFY02765.1 - 0.00011 22.0 0.0 0.0019 17.8 0.0 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 KFY02765.1 - 0.00023 20.6 0.0 0.00069 19.0 0.0 1.8 2 0 0 2 2 2 1 FAD binding domain NAD_binding_9 PF13454.6 KFY02765.1 - 0.00051 20.1 0.1 0.044 13.8 0.0 2.5 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.14 KFY02765.1 - 0.00055 19.3 0.0 0.0033 16.7 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KFY02765.1 - 0.0069 15.5 0.1 0.016 14.3 0.0 1.6 2 0 0 2 2 2 1 FAD binding domain Trp_halogenase PF04820.14 KFY02765.1 - 0.011 14.6 0.0 0.016 14.0 0.0 1.3 1 0 0 1 1 1 0 Tryptophan halogenase K_oxygenase PF13434.6 KFY02765.1 - 0.089 11.9 0.9 0.32 10.1 0.1 2.1 3 0 0 3 3 3 0 L-lysine 6-monooxygenase (NADPH-requiring) HI0933_like PF03486.14 KFY02765.1 - 0.093 11.4 0.0 0.34 9.6 0.0 1.9 2 0 0 2 2 2 0 HI0933-like protein Pyr_redox PF00070.27 KFY02765.1 - 0.15 12.6 0.3 0.97 10.0 0.0 2.5 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase PDH_E1_M PF17831.1 KFY02767.1 - 0.16 11.4 0.0 0.26 10.8 0.0 1.2 1 0 0 1 1 1 0 Pyruvate dehydrogenase E1 component middle domain DSBA PF01323.20 KFY02768.1 - 2.5e-16 60.0 0.0 2.9e-16 59.8 0.0 1.0 1 0 0 1 1 1 1 DSBA-like thioredoxin domain Lactococcin PF04369.13 KFY02768.1 - 0.062 13.4 0.0 0.12 12.5 0.0 1.5 1 0 0 1 1 1 0 Lactococcin-like family adh_short PF00106.25 KFY02769.1 - 1.7e-36 125.6 0.0 3e-36 124.7 0.0 1.4 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 KFY02769.1 - 1.2e-27 97.0 0.0 1.5e-27 96.7 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase 3HCDH_N PF02737.18 KFY02769.1 - 0.00053 19.9 0.1 0.00081 19.3 0.1 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain KR PF08659.10 KFY02769.1 - 0.0051 16.7 0.0 0.0076 16.2 0.0 1.3 1 0 0 1 1 1 1 KR domain F420_oxidored PF03807.17 KFY02769.1 - 0.11 13.0 0.1 0.22 12.1 0.1 1.5 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Polysacc_synt_2 PF02719.15 KFY02769.1 - 0.13 11.3 0.0 0.24 10.5 0.0 1.4 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Shikimate_DH PF01488.20 KFY02769.1 - 0.2 11.7 0.0 0.33 11.0 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Glyco_hydro2_C5 PF18565.1 KFY02770.1 - 4.3e-30 103.6 0.3 8.9e-30 102.6 0.3 1.6 1 0 0 1 1 1 1 Glycoside hydrolase family 2 C-terminal domain 5 Glyco_hydro_2_C PF02836.17 KFY02770.1 - 5.8e-27 94.6 0.0 1.3e-26 93.4 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain DUF4982 PF16355.5 KFY02770.1 - 3.3e-22 78.2 0.1 7.6e-22 77.0 0.1 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4982) Glyco_hydro_2 PF00703.21 KFY02770.1 - 3.7e-17 63.0 0.3 7.7e-17 62.0 0.3 1.6 1 0 0 1 1 1 1 Glycosyl hydrolases family 2 Glyco_hydro_2_N PF02837.18 KFY02770.1 - 5.8e-16 58.9 0.0 6.5e-15 55.4 0.0 2.5 2 0 0 2 2 2 1 Glycosyl hydrolases family 2, sugar binding domain BetaGal_dom4_5 PF13364.6 KFY02770.1 - 5.2e-05 23.8 0.0 0.0015 19.1 0.0 2.6 2 0 0 2 2 2 1 Beta-galactosidase jelly roll domain Invasin_D3 PF09134.10 KFY02770.1 - 0.027 14.8 8.4 0.26 11.6 2.1 2.9 2 0 0 2 2 2 0 Invasin, domain 3 FAD_binding_4 PF01565.23 KFY02771.1 - 2.3e-20 72.8 0.4 5.8e-20 71.5 0.4 1.7 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 KFY02771.1 - 0.032 14.3 0.0 0.074 13.2 0.0 1.6 1 0 0 1 1 1 0 Berberine and berberine like PTR2 PF00854.21 KFY02772.1 - 2.3e-79 267.1 8.3 3.1e-79 266.6 8.3 1.1 1 0 0 1 1 1 1 POT family CE2_N PF17996.1 KFY02775.1 - 1.9e-20 72.9 0.1 3.5e-20 72.0 0.1 1.4 1 0 0 1 1 1 1 Carbohydrate esterase 2 N-terminal Lipase_GDSL_2 PF13472.6 KFY02775.1 - 7.7e-15 55.7 2.3 1.2e-14 55.1 2.3 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family CBM_1 PF00734.18 KFY02775.1 - 4.6e-14 52.1 8.2 1e-13 50.9 8.2 1.7 1 0 0 1 1 1 1 Fungal cellulose binding domain Lipase_GDSL PF00657.22 KFY02775.1 - 7.4e-06 26.1 0.1 1.2e-05 25.4 0.1 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Sugar_tr PF00083.24 KFY02776.1 - 4.7e-97 325.7 26.5 5.7e-97 325.4 26.5 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KFY02776.1 - 1.3e-34 119.8 45.8 9.9e-31 106.9 21.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily GST_N_3 PF13417.6 KFY02776.1 - 9.1e-06 26.0 0.0 2.2e-05 24.8 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 KFY02776.1 - 0.0028 17.8 0.0 0.0057 16.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain OATP PF03137.20 KFY02776.1 - 0.0064 14.8 0.5 0.0064 14.8 0.5 2.1 1 1 1 2 2 2 1 Organic Anion Transporter Polypeptide (OATP) family GST_N_2 PF13409.6 KFY02776.1 - 0.0077 16.5 0.0 0.016 15.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 KFY02776.1 - 0.019 15.2 0.0 0.048 13.9 0.0 1.7 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 KFY02776.1 - 0.065 13.3 0.0 0.2 11.7 0.0 1.8 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain DUF2615 PF11027.8 KFY02776.1 - 1.8 8.7 5.6 5.2 7.3 0.1 3.4 3 1 1 4 4 4 0 Protein of unknown function (DUF2615) OPT PF03169.15 KFY02777.1 - 1.5e-88 298.0 45.9 1.8e-88 297.7 45.9 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein YchF-GTPase_C PF06071.13 KFY02778.1 - 8.5e-37 125.2 0.1 2.1e-36 124.0 0.1 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF933) MMR_HSR1 PF01926.23 KFY02778.1 - 7.2e-21 74.4 0.0 1.9e-20 73.0 0.0 1.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 KFY02778.1 - 9.3e-07 28.5 0.0 1.7e-06 27.6 0.0 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B Mcp5_PH PF12814.7 KFY02779.1 - 6.3e-45 152.2 0.1 1.2e-44 151.4 0.1 1.5 1 0 0 1 1 1 1 Meiotic cell cortex C-terminal pleckstrin homology PH PF00169.29 KFY02779.1 - 0.00033 21.1 0.1 0.0012 19.3 0.0 2.0 2 0 0 2 2 2 1 PH domain SOGA PF11365.8 KFY02779.1 - 0.0095 17.0 2.6 0.0095 17.0 2.6 4.3 2 2 2 4 4 4 2 Protein SOGA TPR_MLP1_2 PF07926.12 KFY02779.1 - 4.3 7.4 34.5 3 7.9 0.1 4.7 3 1 1 4 4 4 0 TPR/MLP1/MLP2-like protein Zn_clus PF00172.18 KFY02783.1 - 1.8e-09 37.6 8.4 2.6e-09 37.1 8.4 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SnoaL_4 PF13577.6 KFY02784.1 - 3.8e-15 56.1 0.0 4.7e-15 55.8 0.0 1.1 1 0 0 1 1 1 1 SnoaL-like domain Ring_hydroxyl_B PF00866.18 KFY02784.1 - 0.08 13.0 0.0 0.12 12.4 0.0 1.2 1 0 0 1 1 1 0 Ring hydroxylating beta subunit MFS_1 PF07690.16 KFY02785.1 - 1.6e-17 63.5 45.0 1.6e-17 63.5 45.0 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily Amidase PF01425.21 KFY02786.1 - 2.8e-68 230.9 0.1 1.5e-67 228.6 0.1 1.9 1 1 0 1 1 1 1 Amidase ADH_zinc_N PF00107.26 KFY02787.1 - 0.00027 20.9 0.0 0.0021 18.0 0.0 2.2 1 1 0 1 1 1 1 Zinc-binding dehydrogenase Peptidase_S28 PF05577.12 KFY02788.1 - 1.1e-52 179.3 1.1 1.4e-38 132.9 0.1 2.1 2 0 0 2 2 2 2 Serine carboxypeptidase S28 Peptidase_S9 PF00326.21 KFY02788.1 - 0.14 11.6 0.1 17 4.8 0.0 2.4 2 1 1 3 3 3 0 Prolyl oligopeptidase family adh_short PF00106.25 KFY02789.1 - 2.1e-24 86.1 0.0 4.7e-20 71.9 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KFY02789.1 - 4.7e-13 49.3 0.1 5.1e-10 39.3 0.0 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KFY02789.1 - 2.2e-05 24.4 0.0 5.1e-05 23.3 0.0 1.6 2 0 0 2 2 2 1 KR domain Epimerase PF01370.21 KFY02789.1 - 0.024 14.1 0.0 0.097 12.1 0.0 1.8 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KFY02789.1 - 0.12 11.7 0.0 0.28 10.5 0.0 1.6 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase SWI-SNF_Ssr4 PF08549.10 KFY02789.1 - 0.39 9.3 0.4 0.85 8.2 0.1 1.6 2 0 0 2 2 2 0 Fungal domain of unknown function (DUF1750) Aldo_ket_red PF00248.21 KFY02790.1 - 1.9e-64 217.7 0.0 2.4e-64 217.4 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family HIP1_clath_bdg PF16515.5 KFY02793.1 - 0.034 14.8 24.6 0.24 12.0 3.6 3.9 2 2 2 4 4 4 0 Clathrin-binding domain of Huntingtin-interacting protein 1 DUF3887 PF13026.6 KFY02793.1 - 0.15 12.9 1.5 1.2 10.0 0.5 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3887) FAM184 PF15665.5 KFY02793.1 - 7.9 6.2 23.2 4.3 7.1 12.9 2.2 1 1 1 2 2 2 0 Family with sequence similarity 184, A and B Cyclin_N PF00134.23 KFY02801.1 - 2.3e-14 53.2 0.2 5.5e-14 52.0 0.0 1.8 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin PF08613.11 KFY02801.1 - 1.5e-06 28.7 0.5 1.4e-05 25.5 0.1 2.5 2 1 0 2 2 2 1 Cyclin DUF3920 PF13058.6 KFY02801.1 - 0.25 11.5 1.9 0.24 11.6 0.3 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3920) Nuc_sug_transp PF04142.15 KFY02802.1 - 9.5e-104 346.9 13.3 1.3e-103 346.5 13.3 1.1 1 0 0 1 1 1 1 Nucleotide-sugar transporter EamA PF00892.20 KFY02802.1 - 1.5e-06 28.4 26.7 0.00019 21.6 4.1 2.4 2 0 0 2 2 2 2 EamA-like transporter family UAA PF08449.11 KFY02802.1 - 2.7e-06 26.8 13.9 1.5e-05 24.4 13.9 2.1 1 1 0 1 1 1 1 UAA transporter family EmrE PF13536.6 KFY02802.1 - 0.0066 16.1 0.1 0.0066 16.1 0.1 2.2 2 1 0 2 2 2 1 Putative multidrug resistance efflux transporter TPT PF03151.16 KFY02802.1 - 0.014 14.7 13.2 0.043 13.2 7.7 2.2 2 0 0 2 2 2 0 Triose-phosphate Transporter family DMT_6 PF04342.12 KFY02802.1 - 0.39 11.0 7.9 3.7 7.8 0.4 2.7 2 0 0 2 2 2 0 Putative member of DMT superfamily (DUF486) TMEM234 PF10639.9 KFY02802.1 - 2.1 8.4 7.9 0.55 10.3 0.3 2.5 2 0 0 2 2 2 0 Putative transmembrane family 234 HPP PF04982.13 KFY02802.1 - 7.4 6.8 11.1 0.43 10.8 0.1 3.3 3 1 0 3 3 3 0 HPP family Sec63 PF02889.16 KFY02803.1 - 3.1e-29 101.9 0.0 4.5e-29 101.4 0.0 1.2 1 0 0 1 1 1 1 Sec63 Brl domain DEAD PF00270.29 KFY02803.1 - 2e-22 79.8 0.0 4.2e-22 78.8 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 KFY02803.1 - 7.8e-10 39.0 0.0 2.4e-09 37.4 0.0 1.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 KFY02803.1 - 6.9e-07 29.6 0.0 2.6e-06 27.8 0.0 2.0 1 1 0 1 1 1 1 Helicase conserved C-terminal domain HHH_5 PF14520.6 KFY02803.1 - 0.00023 21.7 0.0 0.00066 20.2 0.0 1.8 1 0 0 1 1 1 1 Helix-hairpin-helix domain AAA_19 PF13245.6 KFY02803.1 - 0.00099 19.5 0.0 0.011 16.0 0.0 2.4 2 0 0 2 2 2 1 AAA domain Cdd1 PF11731.8 KFY02803.1 - 0.0017 18.6 0.0 0.0057 16.9 0.0 1.9 1 0 0 1 1 1 1 Pathogenicity locus UvrD-helicase PF00580.21 KFY02803.1 - 0.039 13.5 1.7 0.073 12.6 0.0 2.3 4 0 0 4 4 4 0 UvrD/REP helicase N-terminal domain AAA_22 PF13401.6 KFY02803.1 - 0.062 13.6 0.0 0.16 12.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain PDR_CDR PF06422.12 KFY02805.1 - 0.0012 18.6 0.0 0.0016 18.3 0.0 1.2 1 0 0 1 1 1 1 CDR ABC transporter DUF4562 PF15123.6 KFY02805.1 - 0.0037 17.2 0.0 0.0045 16.9 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4562) VirB8 PF04335.13 KFY02805.1 - 0.012 15.5 0.0 0.015 15.1 0.0 1.1 1 0 0 1 1 1 0 VirB8 protein DUF2417 PF10329.9 KFY02805.1 - 0.15 11.5 0.0 0.17 11.3 0.0 1.0 1 0 0 1 1 1 0 Region of unknown function (DUF2417) Ferric_reduct PF01794.19 KFY02806.1 - 8.7e-18 64.6 6.1 8.7e-18 64.6 6.1 2.2 3 0 0 3 3 3 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 KFY02806.1 - 9.5e-16 58.3 0.0 7.2e-10 39.2 0.0 2.3 2 0 0 2 2 2 2 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 KFY02806.1 - 3.3e-11 43.2 0.0 8.4e-11 41.9 0.0 1.7 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_1 PF00175.21 KFY02806.1 - 0.005 17.5 0.0 6.6 7.4 0.0 2.5 2 0 0 2 2 2 2 Oxidoreductase NAD-binding domain AIM3 PF17096.5 KFY02806.1 - 0.047 14.6 0.1 0.047 14.6 0.1 4.2 2 1 1 3 3 3 0 Altered inheritance of mitochondria protein 3 DUF4405 PF14358.6 KFY02806.1 - 1.2 9.8 6.9 0.16 12.5 1.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4405) GDI PF00996.18 KFY02807.1 - 2e-23 82.7 0.0 1.1e-22 80.2 0.0 1.9 1 1 0 1 1 1 1 GDP dissociation inhibitor Ldh_2 PF02615.14 KFY02808.1 - 1.7e-122 408.7 1.8 2.1e-122 408.5 1.8 1.1 1 0 0 1 1 1 1 Malate/L-lactate dehydrogenase ING PF12998.7 KFY02811.1 - 0.00049 20.6 0.6 0.0027 18.3 0.6 2.2 1 1 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding DUF4404 PF14357.6 KFY02811.1 - 1.6 9.4 4.3 6.8 7.4 0.0 3.2 2 1 1 3 3 3 0 Domain of unknown function (DUF4404) DUF3294 PF07957.11 KFY02812.1 - 0.013 15.3 0.7 0.026 14.3 0.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3294) DNTTIP1_dimer PF18192.1 KFY02812.1 - 0.089 13.2 0.0 0.21 12.0 0.0 1.6 1 0 0 1 1 1 0 DNTTIP1 dimerisation domain PCP_red PF08369.10 KFY02812.1 - 0.12 12.6 0.1 0.12 12.6 0.1 2.1 2 0 0 2 2 2 0 Proto-chlorophyllide reductase 57 kD subunit Rtf2 PF04641.12 KFY02812.1 - 2.1 7.7 5.0 0.23 10.8 0.5 1.7 2 0 0 2 2 2 0 Rtf2 RING-finger Cu-oxidase_2 PF07731.14 KFY02819.1 - 3.3e-44 150.0 6.2 1.8e-40 137.8 1.1 3.3 2 1 0 2 2 2 2 Multicopper oxidase Cu-oxidase_3 PF07732.15 KFY02819.1 - 2e-40 137.5 1.7 3.6e-37 127.0 0.3 3.2 3 0 0 3 3 3 2 Multicopper oxidase Cu-oxidase PF00394.22 KFY02819.1 - 2.7e-37 128.4 1.6 6.6e-35 120.6 0.2 2.8 3 0 0 3 3 3 2 Multicopper oxidase Cupredoxin_1 PF13473.6 KFY02819.1 - 0.0036 17.4 0.0 14 5.8 0.0 3.9 3 2 0 3 3 3 2 Cupredoxin-like domain FA_hydroxylase PF04116.13 KFY02824.1 - 7.7e-18 65.1 1.4 7.7e-18 65.1 1.4 1.7 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily Stn1 PF10451.9 KFY02824.1 - 0.1 11.6 0.0 0.14 11.1 0.0 1.2 1 0 0 1 1 1 0 Telomere regulation protein Stn1 YfiO PF13525.6 KFY02825.1 - 0.079 12.7 0.0 0.12 12.1 0.0 1.2 1 0 0 1 1 1 0 Outer membrane lipoprotein FAD_binding_3 PF01494.19 KFY02826.1 - 1.3e-29 103.5 0.0 2.8e-29 102.5 0.0 1.5 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.24 KFY02826.1 - 5.2e-05 23.0 0.1 0.041 13.5 0.1 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase SE PF08491.10 KFY02826.1 - 8.5e-05 21.7 0.0 0.027 13.6 0.0 2.2 2 0 0 2 2 2 2 Squalene epoxidase Pyr_redox_2 PF07992.14 KFY02826.1 - 0.00046 19.5 0.0 0.31 10.2 0.0 2.3 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KFY02826.1 - 0.0016 17.5 0.0 0.19 10.7 0.0 2.8 3 0 0 3 3 3 1 Lycopene cyclase protein Pyr_redox PF00070.27 KFY02826.1 - 0.0041 17.6 0.1 4.3 8.0 0.0 2.6 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KFY02826.1 - 0.0078 16.4 0.1 0.018 15.3 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Myosin_N PF02736.19 KFY02826.1 - 0.016 15.0 1.0 5.3 7.0 0.1 2.4 2 0 0 2 2 2 0 Myosin N-terminal SH3-like domain FAD_binding_2 PF00890.24 KFY02826.1 - 0.075 12.1 0.0 0.48 9.5 0.0 2.0 2 0 0 2 2 2 0 FAD binding domain NAD_binding_10 PF13460.6 KFY02827.1 - 2.7e-34 118.6 0.0 3.2e-34 118.4 0.0 1.0 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KFY02827.1 - 4.9e-08 32.7 0.0 8.3e-08 32.0 0.0 1.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.13 KFY02827.1 - 1.1e-06 28.4 0.1 1.5e-06 27.9 0.1 1.3 1 0 0 1 1 1 1 NmrA-like family RmlD_sub_bind PF04321.17 KFY02827.1 - 0.038 13.1 0.0 0.064 12.3 0.0 1.4 1 0 0 1 1 1 0 RmlD substrate binding domain TrkA_N PF02254.18 KFY02827.1 - 0.058 13.6 0.0 0.2 11.9 0.0 2.0 2 1 0 2 2 2 0 TrkA-N domain GDP_Man_Dehyd PF16363.5 KFY02827.1 - 0.11 11.9 0.0 0.2 11.0 0.0 1.5 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase Sacchrp_dh_NADP PF03435.18 KFY02827.1 - 0.11 12.7 0.0 0.2 12.0 0.0 1.5 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain FTR1 PF03239.14 KFY02828.1 - 1.2e-81 274.3 6.9 1.8e-81 273.7 6.9 1.2 1 0 0 1 1 1 1 Iron permease FTR1 family Fungal_trans PF04082.18 KFY02828.1 - 2.6e-13 49.6 0.1 5e-13 48.7 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain GPI2 PF06432.11 KFY02828.1 - 0.6 9.5 2.6 0.75 9.2 0.6 2.2 2 0 0 2 2 2 0 Phosphatidylinositol N-acetylglucosaminyltransferase Phage_holin_8 PF16931.5 KFY02828.1 - 4.4 7.3 7.0 1.5 8.8 2.9 2.4 2 0 0 2 2 2 0 Putative phage holin Helo_like_N PF17111.5 KFY02830.1 - 1.4e-74 250.0 12.1 1.6e-72 243.3 4.0 2.2 2 0 0 2 2 2 2 Fungal N-terminal domain of STAND proteins RPW8 PF05659.11 KFY02830.1 - 0.0083 15.8 2.2 2.5 7.8 0.1 2.7 2 0 0 2 2 2 2 Arabidopsis broad-spectrum mildew resistance protein RPW8 Occludin_ELL PF07303.13 KFY02830.1 - 0.011 16.4 3.4 0.19 12.5 0.1 3.2 2 1 1 3 3 3 0 Occludin homology domain Syntaxin PF00804.25 KFY02830.1 - 0.027 14.1 4.8 1.8 8.2 0.2 3.6 2 1 2 4 4 4 0 Syntaxin SesA PF17107.5 KFY02830.1 - 0.034 14.4 0.8 0.096 12.9 0.0 2.1 2 1 1 3 3 3 0 N-terminal domain on NACHT_NTPase and P-loop NTPases DUF3829 PF12889.7 KFY02830.1 - 0.046 13.2 4.6 0.1 12.1 1.3 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF3829) DUF1570 PF07607.11 KFY02830.1 - 0.047 14.0 0.3 0.16 12.3 0.0 2.0 2 1 0 2 2 2 0 Protein of unknown function (DUF1570) Syntaxin-6_N PF09177.11 KFY02830.1 - 0.25 11.9 6.7 6.1 7.5 1.2 3.7 2 1 0 2 2 2 0 Syntaxin 6, N-terminal BLOC1_2 PF10046.9 KFY02830.1 - 0.55 10.6 8.1 4.6 7.6 0.3 3.3 5 0 0 5 5 5 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF1451 PF07295.11 KFY02830.1 - 0.64 10.1 4.1 4 7.5 0.1 3.6 3 1 0 3 3 3 0 Zinc-ribbon containing domain GED PF02212.18 KFY02830.1 - 1.5 9.0 5.8 0.3 11.3 0.3 2.7 3 0 0 3 3 3 0 Dynamin GTPase effector domain DUF3450 PF11932.8 KFY02830.1 - 2.1 7.6 7.9 1.2 8.4 0.1 3.2 2 1 1 4 4 4 0 Protein of unknown function (DUF3450) Mod_r PF07200.13 KFY02830.1 - 2.5 8.2 8.6 1 9.4 0.2 3.1 2 1 0 3 3 3 0 Modifier of rudimentary (Mod(r)) protein Spc24 PF08286.11 KFY02830.1 - 5.4 7.3 7.0 3.4 8.0 0.2 3.0 3 0 0 3 3 3 0 Spc24 subunit of Ndc80 DUF724 PF05266.14 KFY02830.1 - 5.6 6.8 9.9 0.66 9.8 0.3 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF724) Abhydrolase_1 PF00561.20 KFY02831.1 - 3.9e-09 36.5 0.0 9.1e-09 35.3 0.0 1.6 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KFY02831.1 - 3.3e-07 31.2 2.5 7.4e-06 26.7 2.5 2.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KFY02831.1 - 0.00012 21.5 0.0 0.001 18.4 0.0 2.1 2 0 0 2 2 2 1 Serine aminopeptidase, S33 DDE_3 PF13358.6 KFY02832.1 - 7.3e-11 42.0 0.0 1.3e-10 41.2 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc3_2 PF01498.18 KFY02832.1 - 3.1e-08 33.7 0.0 9.6e-08 32.2 0.0 1.9 1 0 0 1 1 1 1 Transposase HTH_IclR PF09339.10 KFY02832.1 - 0.00036 20.3 0.1 0.00071 19.3 0.1 1.5 1 0 0 1 1 1 1 IclR helix-turn-helix domain HTH_23 PF13384.6 KFY02832.1 - 0.00065 19.4 0.9 0.06 13.2 0.0 3.0 2 0 0 2 2 2 1 Homeodomain-like domain HTH_24 PF13412.6 KFY02832.1 - 0.002 17.6 0.0 0.12 12.0 0.0 2.4 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding Sigma70_r4_2 PF08281.12 KFY02832.1 - 0.012 15.3 0.0 0.029 14.0 0.0 1.6 1 0 0 1 1 1 0 Sigma-70, region 4 HTH_40 PF14493.6 KFY02832.1 - 0.024 15.1 0.1 0.071 13.6 0.0 1.8 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_5 PF01022.20 KFY02832.1 - 0.027 14.3 0.1 0.047 13.6 0.1 1.3 1 0 0 1 1 1 0 Bacterial regulatory protein, arsR family HTH_20 PF12840.7 KFY02832.1 - 0.032 14.3 0.0 0.078 13.1 0.0 1.6 2 0 0 2 2 1 0 Helix-turn-helix domain HTH_10 PF04967.12 KFY02832.1 - 0.096 12.5 0.0 0.44 10.4 0.0 2.0 2 0 0 2 2 2 0 HTH DNA binding domain HTH_49 PF18010.1 KFY02832.1 - 0.12 12.2 0.1 0.88 9.5 0.0 2.1 2 0 0 2 2 2 0 Cry35Ab1 HTH C-terminal domain MarR_2 PF12802.7 KFY02832.1 - 0.14 12.1 0.1 1.2 9.1 0.1 2.1 2 0 0 2 2 2 0 MarR family Zn_clus PF00172.18 KFY02833.1 - 3.9e-07 30.1 6.5 6.5e-07 29.4 6.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CFEM PF05730.11 KFY02834.1 - 4.8e-09 36.2 10.3 9e-09 35.3 10.3 1.5 1 0 0 1 1 1 1 CFEM domain DUF4662 PF15578.6 KFY02834.1 - 0.11 12.2 0.2 0.19 11.5 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4662) Autophagy_C PF10381.9 KFY02834.1 - 6.2 6.4 8.1 14 5.3 1.9 2.5 2 0 0 2 2 2 0 Autophagocytosis associated protein C-terminal Phage_holin_2_2 PF10746.9 KFY02835.1 - 0.042 13.5 0.4 0.15 11.7 0.4 1.9 1 0 0 1 1 1 0 Phage holin T7 family, holin superfamily II Amidohydro_1 PF01979.20 KFY02839.1 - 1.6e-17 63.9 0.0 1.2e-11 44.5 0.0 2.4 2 1 0 2 2 2 2 Amidohydrolase family Amidohydro_3 PF07969.11 KFY02839.1 - 6.2e-16 58.9 0.2 1.6e-09 37.8 0.0 2.3 2 0 0 2 2 2 2 Amidohydrolase family Exo_endo_phos PF03372.23 KFY02839.1 - 0.01 15.4 0.0 0.03 13.8 0.0 1.8 1 1 0 1 1 1 0 Endonuclease/Exonuclease/phosphatase family adh_short PF00106.25 KFY02840.1 - 5.2e-40 137.0 0.3 7.7e-40 136.4 0.3 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KFY02840.1 - 6.1e-28 98.0 1.0 8.4e-28 97.5 1.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.6 KFY02840.1 - 1.6e-05 24.9 0.2 3.3e-05 23.8 0.2 1.7 1 0 0 1 1 1 1 NAD(P)H-binding ADH_zinc_N PF00107.26 KFY02840.1 - 0.0087 16.0 0.7 0.021 14.8 0.6 1.7 1 1 0 1 1 1 1 Zinc-binding dehydrogenase SRR1 PF07985.12 KFY02841.1 - 1.1e-13 51.0 0.0 1.7e-13 50.4 0.0 1.3 1 0 0 1 1 1 1 SRR1 RRP7 PF12923.7 KFY02841.1 - 0.05 13.7 2.4 0.099 12.8 2.4 1.5 1 1 0 1 1 1 0 Ribosomal RNA-processing protein 7 (RRP7) C-terminal domain DDOST_48kD PF03345.14 KFY02843.1 - 2.1e-161 537.4 0.0 2.4e-161 537.2 0.0 1.0 1 0 0 1 1 1 1 Oligosaccharyltransferase 48 kDa subunit beta Pet191_N PF10203.9 KFY02844.1 - 2.5e-17 62.9 0.4 3.2e-17 62.6 0.4 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein PET191 Ank_2 PF12796.7 KFY02845.1 - 2.1e-122 400.0 30.1 3.5e-17 62.7 0.1 12.6 5 3 8 13 13 13 13 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KFY02845.1 - 2.6e-93 305.3 27.2 1.1e-09 38.6 0.0 17.0 7 5 12 19 19 19 18 Ankyrin repeats (many copies) Ank PF00023.30 KFY02845.1 - 1.3e-90 294.2 65.2 3.7e-05 24.0 0.2 23.9 23 1 1 24 24 24 19 Ankyrin repeat Ank_3 PF13606.6 KFY02845.1 - 4.1e-84 266.4 36.0 4.4e-05 23.6 0.0 24.1 23 1 1 24 24 24 21 Ankyrin repeat Ank_5 PF13857.6 KFY02845.1 - 7.9e-81 265.1 33.3 2.4e-07 30.9 0.1 18.8 7 5 13 20 20 20 18 Ankyrin repeats (many copies) PGAP1 PF07819.13 KFY02845.1 - 0.015 15.0 0.0 0.11 12.2 0.0 2.0 2 0 0 2 2 2 0 PGAP1-like protein VWA_3_C PF18571.1 KFY02845.1 - 0.97 9.4 6.7 8.6 6.3 0.0 5.8 6 0 0 6 6 6 0 von Willebrand factor type A C-terminal domain PT PF04886.12 KFY02845.1 - 2.6 7.7 6.4 4.9 6.8 6.4 1.4 1 0 0 1 1 1 0 PT repeat Hep_59 PF07052.11 KFY02846.1 - 8.6e-10 39.3 0.0 1.6e-09 38.5 0.0 1.4 1 0 0 1 1 1 1 Hepatocellular carcinoma-associated antigen 59 TraC PF07820.12 KFY02846.1 - 0.14 12.5 3.6 4.3 7.7 0.4 2.9 2 0 0 2 2 2 0 TraC-like protein Acylphosphatase PF00708.18 KFY02847.1 - 8.5e-20 71.0 1.5 9.7e-20 70.8 1.5 1.0 1 0 0 1 1 1 1 Acylphosphatase Ank_2 PF12796.7 KFY02848.1 - 2e-23 82.8 0.1 9.9e-13 48.5 0.1 3.8 2 1 2 4 4 4 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KFY02848.1 - 1e-19 70.6 0.1 8.8e-07 29.4 0.0 4.2 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank PF00023.30 KFY02848.1 - 4.6e-17 61.6 0.0 0.0026 18.1 0.0 5.3 5 0 0 5 5 5 4 Ankyrin repeat Ank_3 PF13606.6 KFY02848.1 - 1.9e-14 52.3 0.0 0.027 15.0 0.0 5.6 5 0 0 5 5 5 4 Ankyrin repeat Ank_5 PF13857.6 KFY02848.1 - 1.7e-13 50.5 0.4 7.2e-06 26.2 0.1 3.0 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Glyco_hydro_12 PF01670.16 KFY02849.1 - 1.4e-43 149.4 11.2 1.6e-43 149.2 11.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 12 Phage_holin_5_1 PF06946.11 KFY02849.1 - 2.8 8.4 5.9 0.5 10.8 1.2 2.2 2 1 0 2 2 2 0 Bacteriophage A118-like holin, Hol118 FAA_hydrolase PF01557.18 KFY02850.1 - 6.6e-53 179.6 0.0 7.7e-53 179.4 0.0 1.0 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family NUDIX PF00293.28 KFY02853.1 - 3.8e-08 33.4 0.0 9.9e-08 32.1 0.0 1.8 1 1 0 1 1 1 1 NUDIX domain PWI PF01480.17 KFY02854.1 - 7.3e-31 106.3 0.0 1.2e-30 105.7 0.0 1.3 1 0 0 1 1 1 1 PWI domain DEAD PF00270.29 KFY02856.1 - 5.4e-21 75.1 0.0 1.2e-20 74.0 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KFY02856.1 - 5.4e-18 65.4 0.0 1.3e-16 60.9 0.0 2.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain RQC PF09382.10 KFY02856.1 - 5.5e-18 64.8 0.5 3.2e-17 62.4 0.2 2.3 2 0 0 2 2 2 1 RQC domain RecQ_Zn_bind PF16124.5 KFY02856.1 - 1.5e-16 60.9 6.5 5.4e-16 59.1 6.5 2.1 1 0 0 1 1 1 1 RecQ zinc-binding ResIII PF04851.15 KFY02856.1 - 9.5e-05 22.5 0.0 0.00034 20.7 0.0 2.0 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit HRDC PF00570.23 KFY02856.1 - 0.016 15.2 0.0 0.049 13.6 0.0 1.9 1 0 0 1 1 1 0 HRDC domain APH PF01636.23 KFY02857.1 - 0.026 14.5 0.0 0.061 13.2 0.0 1.7 1 1 0 1 1 1 0 Phosphotransferase enzyme family Abhydrolase_1 PF00561.20 KFY02858.1 - 1.6e-07 31.3 0.1 2.1e-06 27.6 0.1 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KFY02858.1 - 0.00033 21.3 0.0 0.00045 20.9 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF3846 PF12957.7 KFY02858.1 - 0.14 12.5 0.0 0.26 11.6 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3846) Glyco_tranf_2_3 PF13641.6 KFY02860.1 - 2.7e-19 70.0 0.0 3.5e-19 69.6 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.6 KFY02860.1 - 4.1e-06 26.4 0.0 8e-06 25.4 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.26 KFY02860.1 - 1.3e-05 25.1 0.0 1.8e-05 24.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 2 Abhydrolase_1 PF00561.20 KFY02861.1 - 5.6e-14 52.4 0.2 1.3e-13 51.2 0.2 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KFY02861.1 - 2e-10 41.6 3.8 2.7e-10 41.2 3.8 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KFY02861.1 - 2.2e-08 33.6 0.0 2.1e-07 30.5 0.0 2.0 1 1 0 1 1 1 1 Serine aminopeptidase, S33 DLH PF01738.18 KFY02861.1 - 0.0051 16.4 0.0 0.25 10.9 0.0 2.3 2 0 0 2 2 2 1 Dienelactone hydrolase family Esterase PF00756.20 KFY02861.1 - 0.0058 16.3 0.0 0.0096 15.6 0.0 1.4 1 0 0 1 1 1 1 Putative esterase Abhydrolase_2 PF02230.16 KFY02861.1 - 0.06 13.1 0.0 0.16 11.8 0.0 1.6 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase PhoPQ_related PF10142.9 KFY02861.1 - 0.11 11.1 0.0 0.16 10.6 0.0 1.1 1 0 0 1 1 1 0 PhoPQ-activated pathogenicity-related protein FSH1 PF03959.13 KFY02861.1 - 0.21 11.2 0.0 0.88 9.2 0.0 1.9 1 1 0 1 1 1 0 Serine hydrolase (FSH1) DUF915 PF06028.11 KFY02861.1 - 0.21 10.9 0.0 0.53 9.6 0.0 1.6 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) Fungal_trans_2 PF11951.8 KFY02862.1 - 1.6e-15 56.8 0.3 2.2e-15 56.4 0.3 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Sugar_tr PF00083.24 KFY02863.1 - 1.4e-82 278.0 7.1 6.2e-82 275.9 7.1 1.8 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KFY02863.1 - 4.4e-13 48.9 30.4 1.3e-12 47.4 21.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 KFY02863.1 - 0.00034 19.3 0.4 0.00034 19.3 0.4 3.5 3 1 1 4 4 4 1 MFS/sugar transport protein PUCC PF03209.15 KFY02863.1 - 0.0013 17.8 0.6 0.0025 16.9 0.6 1.4 1 0 0 1 1 1 1 PUCC protein Ank PF00023.30 KFY02864.1 - 2.8e-23 81.3 13.4 6.2e-06 26.4 0.1 5.7 5 0 0 5 5 5 5 Ankyrin repeat Ank_2 PF12796.7 KFY02864.1 - 9.3e-23 80.6 8.9 1.2e-13 51.4 1.8 3.0 1 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KFY02864.1 - 3.2e-18 63.9 3.8 0.00018 21.7 0.1 5.9 6 0 0 6 6 5 4 Ankyrin repeat Ank_5 PF13857.6 KFY02864.1 - 6e-17 61.5 10.8 7.2e-06 26.2 0.9 4.9 3 2 2 5 5 5 4 Ankyrin repeats (many copies) Ank_4 PF13637.6 KFY02864.1 - 2.5e-14 53.4 11.2 3.7e-06 27.4 0.5 6.4 3 1 3 6 6 6 5 Ankyrin repeats (many copies) TPR_8 PF13181.6 KFY02864.1 - 0.003 17.6 4.0 0.0031 17.6 0.6 2.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_MalT PF17874.1 KFY02864.1 - 0.0043 16.5 0.7 0.01 15.2 0.3 1.7 2 0 0 2 2 2 1 MalT-like TPR region TPR_12 PF13424.6 KFY02864.1 - 0.016 15.4 0.5 0.016 15.4 0.5 2.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_10 PF13374.6 KFY02864.1 - 0.055 13.3 1.4 0.52 10.3 0.4 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_7 PF13176.6 KFY02864.1 - 0.075 13.1 3.6 0.26 11.4 0.1 3.7 5 0 0 5 5 4 0 Tetratricopeptide repeat TPR_14 PF13428.6 KFY02864.1 - 0.13 13.2 0.9 2.3 9.3 0.2 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_19 PF14559.6 KFY02864.1 - 0.38 11.3 1.9 1.4 9.5 0.3 2.5 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.17 KFY02864.1 - 1.4 9.2 4.3 1.1 9.6 0.8 2.7 3 0 0 3 3 3 0 Tetratricopeptide repeat MFS_1 PF07690.16 KFY02865.1 - 2.5e-42 145.1 69.1 4.3e-39 134.4 58.3 2.8 1 1 1 2 2 2 2 Major Facilitator Superfamily IQCJ-SCHIP1 PF15157.6 KFY02865.1 - 0.11 12.3 0.0 0.2 11.5 0.0 1.3 1 0 0 1 1 1 0 Fusion protein IQCJ-SCHIP1 with IQ-like motif Amino_oxidase PF01593.24 KFY02867.1 - 3.5e-22 79.3 0.0 4.7e-22 78.9 0.0 1.0 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase SARG PF15385.6 KFY02881.1 - 0.02 14.2 0.5 0.035 13.3 0.5 1.3 1 0 0 1 1 1 0 Specifically androgen-regulated gene protein GMC_oxred_N PF00732.19 KFY02882.1 - 6e-47 160.4 0.0 8.3e-47 160.0 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KFY02882.1 - 1.1e-32 113.6 0.1 2e-32 112.7 0.1 1.4 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.12 KFY02882.1 - 8.8e-06 25.0 0.0 1.3e-05 24.4 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein DAO PF01266.24 KFY02882.1 - 8.8e-05 22.2 0.0 0.025 14.2 0.0 2.7 2 1 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KFY02882.1 - 0.00054 19.2 0.0 0.099 11.7 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 KFY02882.1 - 0.0014 18.8 0.6 0.0072 16.5 0.0 2.6 4 0 0 4 4 4 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KFY02882.1 - 0.0015 17.8 0.0 0.013 14.8 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 KFY02882.1 - 0.0017 17.5 0.0 0.16 11.0 0.0 2.1 2 0 0 2 2 2 1 Glucose inhibited division protein A Pyr_redox_3 PF13738.6 KFY02882.1 - 0.073 12.3 0.0 12 5.0 0.0 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KFY02882.1 - 0.085 11.5 0.0 1.6 7.4 0.0 2.2 2 0 0 2 2 2 0 HI0933-like protein FAD_binding_3 PF01494.19 KFY02882.1 - 0.099 11.9 0.0 0.17 11.1 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain Rit1_C PF17184.4 KFY02882.1 - 0.16 11.4 0.1 0.27 10.7 0.1 1.2 1 0 0 1 1 1 0 Rit1 N-terminal domain EHN PF06441.12 KFY02882.1 - 0.17 12.3 0.6 0.61 10.5 0.0 2.2 3 0 0 3 3 3 0 Epoxide hydrolase N terminus GPS PF01825.21 KFY02882.1 - 4.9 7.8 4.8 1.4 9.5 1.5 1.7 2 0 0 2 2 2 0 GPCR proteolysis site, GPS, motif Zn_clus PF00172.18 KFY02883.1 - 3.7e-07 30.2 13.4 1.1e-06 28.6 13.4 1.8 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KFY02883.1 - 3.6e-06 26.2 0.2 9e-06 24.9 0.2 1.7 1 0 0 1 1 1 1 Fungal specific transcription factor domain Ribosomal_L37ae PF01780.19 KFY02883.1 - 1.4 9.0 3.9 1.8 8.7 2.5 1.9 2 0 0 2 2 2 0 Ribosomal L37ae protein family GST_C_3 PF14497.6 KFY02884.1 - 3.5e-17 62.4 0.0 5.9e-17 61.7 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 KFY02884.1 - 4.9e-07 30.0 0.0 1.5e-06 28.4 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 KFY02884.1 - 0.0086 16.1 0.0 0.02 14.9 0.0 1.8 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 KFY02884.1 - 0.036 14.3 0.0 0.058 13.6 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 KFY02884.1 - 0.11 12.8 0.0 0.36 11.1 0.0 2.0 2 1 0 2 2 2 0 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 KFY02885.1 - 4.5e-07 30.1 0.0 1.1e-06 28.9 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain NAD_binding_1 PF00175.21 KFY02885.1 - 3.3e-06 27.7 0.0 7.5e-06 26.6 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 KFY02885.1 - 1.9e-05 24.9 0.0 0.0048 17.2 0.0 2.8 2 1 0 2 2 2 1 Oxidoreductase FAD-binding domain GST_N_3 PF13417.6 KFY02885.1 - 5e-05 23.6 0.0 0.00025 21.4 0.0 2.1 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain NAD_binding_6 PF08030.12 KFY02885.1 - 5.3e-05 23.4 0.0 0.00024 21.2 0.0 2.1 1 1 1 2 2 2 1 Ferric reductase NAD binding domain Putative_PNPOx PF01243.20 KFY02885.1 - 0.00021 21.4 0.0 1 9.6 0.0 3.1 3 1 0 3 3 3 2 Pyridoxamine 5'-phosphate oxidase GST_N_2 PF13409.6 KFY02885.1 - 0.0007 19.8 0.0 0.0029 17.9 0.0 2.1 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 KFY02885.1 - 0.0017 18.5 0.0 0.0039 17.4 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Glyco_hydro_43 PF04616.14 KFY02886.1 - 1.1e-15 57.7 0.2 2.5e-15 56.6 0.2 1.6 1 1 0 1 1 1 1 Glycosyl hydrolases family 43 Zn_clus PF00172.18 KFY02886.1 - 7.8e-10 38.7 10.6 1.5e-09 37.8 10.6 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 KFY02886.1 - 0.00033 19.6 0.1 0.0027 16.6 0.0 2.1 2 0 0 2 2 2 1 Fungal specific transcription factor domain Bac_luciferase PF00296.20 KFY02887.1 - 6.6e-55 186.7 0.2 8.5e-55 186.4 0.2 1.1 1 0 0 1 1 1 1 Luciferase-like monooxygenase Amidohydro_2 PF04909.14 KFY02887.1 - 0.0051 16.6 0.0 0.015 15.1 0.0 1.8 2 0 0 2 2 2 1 Amidohydrolase SSF PF00474.17 KFY02888.1 - 7.5e-22 77.7 30.0 1.4e-21 76.9 30.0 1.4 1 0 0 1 1 1 1 Sodium:solute symporter family ADH_zinc_N PF00107.26 KFY02889.1 - 1.1e-06 28.7 0.1 2.4e-06 27.5 0.1 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KFY02889.1 - 7.2e-05 22.6 0.0 0.00016 21.5 0.0 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Rep_1B PF17873.1 KFY02889.1 - 0.034 14.0 0.1 0.82 9.6 0.0 2.6 2 0 0 2 2 2 0 Replicase polyprotein 1ab Dicty_REP PF05086.12 KFY02889.1 - 0.099 10.6 0.3 0.12 10.3 0.3 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Mucin PF01456.17 KFY02889.1 - 0.93 9.5 5.0 8.2 6.4 0.0 2.3 2 0 0 2 2 2 0 Mucin-like glycoprotein CAP59_mtransfer PF11735.8 KFY02891.1 - 2.6e-69 233.6 0.0 3.4e-69 233.2 0.0 1.1 1 0 0 1 1 1 1 Cryptococcal mannosyltransferase 1 Ndc1_Nup PF09531.10 KFY02892.1 - 0.61 8.7 7.1 0.97 8.0 7.1 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup TMEM154 PF15102.6 KFY02892.1 - 7.1 6.5 10.1 1.8e+02 2.0 10.2 2.7 1 1 0 1 1 1 0 TMEM154 protein family Ribosomal_L14 PF00238.19 KFY02894.1 - 1.8e-47 160.4 1.1 2e-47 160.3 1.1 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e Phage_Mu_Gp45 PF06890.12 KFY02894.1 - 0.096 12.4 0.0 0.12 12.1 0.0 1.3 1 0 0 1 1 1 0 Bacteriophage Mu Gp45 protein SET PF00856.28 KFY02895.1 - 3.3e-09 37.4 0.7 4.4e-07 30.4 0.0 3.0 2 2 1 3 3 3 2 SET domain PPV_E2_N PF00508.17 KFY02895.1 - 0.079 12.3 0.0 0.14 11.5 0.0 1.3 1 0 0 1 1 1 0 E2 (early) protein, N terminal BTB PF00651.31 KFY02896.1 - 0.00015 21.9 0.0 0.00077 19.7 0.0 2.1 2 1 0 2 2 2 1 BTB/POZ domain Anillin PF08174.11 KFY02897.1 - 1.1e-15 58.3 0.0 3.6e-15 56.6 0.0 1.9 1 0 0 1 1 1 1 Cell division protein anillin PH PF00169.29 KFY02897.1 - 3.6e-08 33.9 0.0 1.3e-07 32.0 0.0 2.1 1 0 0 1 1 1 1 PH domain AP-5_subunit_s1 PF15001.6 KFY02897.1 - 1.1 9.2 2.7 0.98 9.4 0.9 1.7 2 0 0 2 2 2 0 AP-5 complex subunit sigma-1 ANAPC_CDC26 PF10471.9 KFY02897.1 - 8.2 7.3 12.4 15 6.5 3.4 4.0 3 0 0 3 3 3 0 Anaphase-promoting complex APC subunit CDC26 RNase_P_pop3 PF08228.11 KFY02898.1 - 1.3e-06 28.5 0.0 2.6e-06 27.6 0.0 1.5 2 0 0 2 2 2 1 RNase P subunit Pop3 GATase PF00117.28 KFY02899.1 - 8.4e-38 130.0 0.0 2.1e-37 128.8 0.0 1.6 2 0 0 2 2 2 1 Glutamine amidotransferase class-I GMP_synt_C PF00958.22 KFY02899.1 - 1.9e-37 127.2 0.0 3.6e-37 126.3 0.0 1.5 1 0 0 1 1 1 1 GMP synthase C terminal domain NAD_synthase PF02540.17 KFY02899.1 - 6e-12 45.2 0.0 3.5e-07 29.6 0.0 2.2 2 0 0 2 2 2 2 NAD synthase Peptidase_C26 PF07722.13 KFY02899.1 - 9.2e-07 28.8 0.0 1.9e-06 27.8 0.0 1.5 1 0 0 1 1 1 1 Peptidase C26 ThiI PF02568.14 KFY02899.1 - 0.0028 17.3 0.3 0.0073 15.9 0.1 1.7 2 0 0 2 2 2 1 Thiamine biosynthesis protein (ThiI) tRNA_Me_trans PF03054.16 KFY02899.1 - 0.0064 15.3 0.1 0.017 13.9 0.1 1.6 2 0 0 2 2 2 1 tRNA methyl transferase QueC PF06508.13 KFY02899.1 - 0.014 14.9 0.0 0.24 10.9 0.0 2.2 2 0 0 2 2 2 0 Queuosine biosynthesis protein QueC PAPS_reduct PF01507.19 KFY02899.1 - 0.096 12.7 0.0 0.16 12.0 0.0 1.4 1 0 0 1 1 1 0 Phosphoadenosine phosphosulfate reductase family ATP_bind_3 PF01171.20 KFY02899.1 - 0.18 11.5 0.0 0.33 10.7 0.0 1.4 1 0 0 1 1 1 0 PP-loop family DUF3517 PF12030.8 KFY02900.1 - 7.6e-101 337.4 1.3 1.4e-99 333.2 0.0 3.0 3 0 0 3 3 3 1 Domain of unknown function (DUF3517) UCH PF00443.29 KFY02900.1 - 2.6e-38 132.0 0.4 5e-38 131.1 0.4 1.5 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KFY02900.1 - 3.1e-19 69.7 1.0 5.6e-19 68.9 0.2 1.9 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase Pox_A3L PF05288.11 KFY02900.1 - 0.15 12.0 2.9 0.15 12.1 0.2 2.5 2 0 0 2 2 2 0 Poxvirus A3L Protein Clathrin PF00637.20 KFY02901.1 - 0.1 12.5 0.1 0.42 10.5 0.0 2.2 2 0 0 2 2 2 0 Region in Clathrin and VPS PPR_3 PF13812.6 KFY02901.1 - 0.15 12.2 0.2 0.9 9.7 0.1 2.3 1 1 1 2 2 2 0 Pentatricopeptide repeat domain COX7a PF02238.15 KFY02902.1 - 4.4e-23 81.4 3.7 5.2e-23 81.2 3.7 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VII Clathrin_lg_ch PF01086.17 KFY02903.1 - 1.6e-75 254.1 8.1 1.8e-75 254.0 8.1 1.0 1 0 0 1 1 1 1 Clathrin light chain CTD_bind PF04818.13 KFY02904.1 - 8.3e-18 65.0 0.1 1.7e-17 64.0 0.1 1.6 1 0 0 1 1 1 1 RNA polymerase II-binding domain. CTK3 PF12243.8 KFY02904.1 - 0.0049 16.9 0.3 0.0098 15.9 0.3 1.4 1 0 0 1 1 1 1 CTD kinase subunit gamma CTK3 DUF3277 PF11681.8 KFY02904.1 - 0.024 14.5 0.1 0.044 13.7 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3277) LepA_C PF06421.12 KFY02904.1 - 0.047 13.9 0.5 3.2 8.0 0.1 2.4 2 0 0 2 2 2 0 GTP-binding protein LepA C-terminus CDC37_N PF03234.14 KFY02905.1 - 4.3e-47 160.2 1.6 4.3e-47 160.2 1.6 3.1 3 1 0 3 3 3 1 Cdc37 N terminal kinase binding CDC37_M PF08565.11 KFY02905.1 - 5.9e-42 142.3 0.3 2.9e-41 140.1 0.0 2.3 3 0 0 3 3 3 1 Cdc37 Hsp90 binding domain CDC37_C PF08564.10 KFY02905.1 - 1.3e-29 102.3 2.9 1.3e-29 102.3 2.9 2.8 2 1 0 2 2 2 1 Cdc37 C terminal domain Seryl_tRNA_N PF02403.22 KFY02905.1 - 1.3 9.3 9.3 0.19 12.0 0.7 3.5 3 0 0 3 3 3 0 Seryl-tRNA synthetase N-terminal domain LUC7 PF03194.15 KFY02905.1 - 1.5 8.4 11.7 0.014 15.1 1.7 2.4 3 0 0 3 3 3 0 LUC7 N_terminus DEAD_2 PF06733.15 KFY02911.1 - 5.7e-58 195.4 1.1 1.1e-57 194.5 0.2 1.9 2 0 0 2 2 2 1 DEAD_2 HBB PF06777.11 KFY02911.1 - 1.3e-49 168.5 2.7 1.3e-45 155.4 0.8 2.6 2 0 0 2 2 2 2 Helical and beta-bridge domain Helicase_C_2 PF13307.6 KFY02911.1 - 5.8e-43 147.0 0.0 2.1e-42 145.2 0.0 2.0 2 0 0 2 2 2 1 Helicase C-terminal domain ResIII PF04851.15 KFY02911.1 - 0.00016 21.7 0.7 0.0036 17.3 0.0 2.8 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.29 KFY02911.1 - 0.002 17.9 0.0 0.28 10.9 0.0 2.4 2 0 0 2 2 2 1 DEAD/DEAH box helicase SNF2_N PF00176.23 KFY02911.1 - 0.04 12.6 0.1 0.53 8.9 0.1 2.3 1 1 0 1 1 1 0 SNF2 family N-terminal domain AAA_22 PF13401.6 KFY02911.1 - 0.062 13.6 0.4 5.5 7.3 0.0 2.9 3 0 0 3 3 3 0 AAA domain UvrD_C PF13361.6 KFY02911.1 - 0.075 12.4 1.3 0.15 11.4 1.3 1.8 1 1 0 1 1 1 0 UvrD-like helicase C-terminal domain PhoH PF02562.16 KFY02911.1 - 0.13 11.7 0.1 6.3 6.2 0.0 2.4 2 0 0 2 2 2 0 PhoH-like protein PRP3 PF08572.10 KFY02912.1 - 2.4e-74 249.8 5.3 3.8e-74 249.2 5.3 1.3 1 0 0 1 1 1 1 pre-mRNA processing factor 3 (PRP3) DUF1115 PF06544.12 KFY02912.1 - 7.7e-49 165.5 1.0 7.7e-49 165.5 1.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF1115) RNA_pol_Rpb1_5 PF04998.17 KFY02913.1 - 5.4e-88 294.9 0.1 9.6e-88 294.1 0.1 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.20 KFY02913.1 - 1.6e-69 233.3 0.1 3.6e-69 232.3 0.1 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.18 KFY02913.1 - 3.1e-35 121.4 0.0 8.5e-35 120.0 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_1 PF04997.12 KFY02913.1 - 2.5e-32 112.5 0.0 2e-30 106.2 0.0 3.2 2 1 0 2 2 2 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_4 PF05000.17 KFY02913.1 - 1e-17 64.1 0.4 3.9e-17 62.1 0.1 2.3 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 4 CCP_MauG PF03150.14 KFY02913.1 - 4.3 8.0 6.9 6.6 7.4 0.3 3.1 1 1 1 3 3 3 0 Di-haem cytochrome c peroxidase EPSP_synthase PF00275.20 KFY02914.1 - 2.9e-130 434.7 0.0 4.1e-130 434.2 0.0 1.2 1 0 0 1 1 1 1 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) DHQ_synthase PF01761.20 KFY02914.1 - 1.6e-101 338.9 0.0 3.1e-101 337.9 0.0 1.5 1 0 0 1 1 1 1 3-dehydroquinate synthase DHquinase_I PF01487.15 KFY02914.1 - 1.8e-55 188.7 0.0 4.2e-55 187.5 0.0 1.6 2 0 0 2 2 2 1 Type I 3-dehydroquinase SKI PF01202.22 KFY02914.1 - 2.9e-37 128.2 0.0 2.7e-35 121.8 0.0 2.3 2 0 0 2 2 2 1 Shikimate kinase Shikimate_dh_N PF08501.11 KFY02914.1 - 1.3e-23 83.0 0.0 3.5e-23 81.6 0.0 1.8 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain Fe-ADH_2 PF13685.6 KFY02914.1 - 7.2e-09 35.7 0.0 1.7e-08 34.5 0.0 1.6 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase SDH_C PF18317.1 KFY02914.1 - 3.1e-08 33.2 0.0 1e-07 31.6 0.0 2.0 1 0 0 1 1 1 1 Shikimate 5'-dehydrogenase C-terminal domain Shikimate_DH PF01488.20 KFY02914.1 - 0.0017 18.4 0.0 0.0038 17.3 0.0 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase AAA_16 PF13191.6 KFY02914.1 - 0.14 12.6 0.1 0.34 11.3 0.1 1.6 1 0 0 1 1 1 0 AAA ATPase domain zf-C2H2 PF00096.26 KFY02915.1 - 1.9e-09 37.4 13.6 0.0032 17.8 1.9 3.8 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFY02915.1 - 2.8e-06 27.7 9.2 0.042 14.7 1.3 3.7 3 0 0 3 3 3 3 C2H2-type zinc finger zf-H2C2_2 PF13465.6 KFY02915.1 - 0.18 12.3 7.8 9.6 6.8 1.2 3.8 3 0 0 3 3 3 0 Zinc-finger double domain zf-BED PF02892.15 KFY02915.1 - 0.26 11.3 1.6 0.71 9.9 1.6 1.8 1 0 0 1 1 1 0 BED zinc finger zf-Di19 PF05605.12 KFY02915.1 - 2 8.8 6.0 2.2 8.7 1.6 2.3 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-CCHC PF00098.23 KFY02919.1 - 5.8e-55 181.0 102.5 5.1e-07 29.5 1.5 11.3 11 0 0 11 11 11 11 Zinc knuckle zf-CCHC_2 PF13696.6 KFY02919.1 - 6.2e-11 41.9 81.9 0.0034 17.2 0.6 12.1 12 0 0 12 12 12 9 Zinc knuckle zf-CCHC_4 PF14392.6 KFY02919.1 - 1.3e-10 40.9 72.7 0.027 14.2 0.4 11.2 11 0 0 11 11 11 10 Zinc knuckle zf-CCHC_3 PF13917.6 KFY02919.1 - 0.00064 19.6 75.4 0.19 11.7 0.2 10.3 2 2 8 10 10 10 7 Zinc knuckle zf-C2H2_10 PF16588.5 KFY02919.1 - 0.0062 16.2 1.7 0.0062 16.2 1.7 10.6 11 0 0 11 11 11 3 C2H2 zinc-finger zf-C2H2 PF00096.26 KFY02920.1 - 0.0039 17.6 19.2 0.061 13.8 0.8 4.7 4 1 0 4 4 4 3 Zinc finger, C2H2 type zf-TRAF PF02176.18 KFY02920.1 - 0.052 14.2 0.7 0.18 12.5 0.7 2.0 1 0 0 1 1 1 0 TRAF-type zinc finger zf-C2H2_4 PF13894.6 KFY02920.1 - 0.082 13.8 19.3 0.27 12.2 0.7 5.2 4 1 0 4 4 4 0 C2H2-type zinc finger Sina PF03145.16 KFY02920.1 - 0.095 12.6 2.9 0.21 11.5 2.9 1.6 1 0 0 1 1 1 0 Seven in absentia protein family zf-H2C2_2 PF13465.6 KFY02920.1 - 5.2 7.7 6.5 9 6.9 0.6 3.1 3 0 0 3 3 3 0 Zinc-finger double domain NmrA PF05368.13 KFY02921.1 - 6.5e-33 114.2 0.0 1e-32 113.5 0.0 1.3 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KFY02921.1 - 1.5e-07 31.5 0.0 2.1e-07 31.0 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KFY02921.1 - 0.0073 15.8 0.0 0.012 15.1 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family TrkA_N PF02254.18 KFY02921.1 - 0.043 14.1 0.0 0.093 13.0 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain Methyltransf_23 PF13489.6 KFY02922.1 - 4.3e-18 65.7 0.0 8.1e-18 64.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KFY02922.1 - 7e-08 33.1 0.0 2.1e-07 31.6 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KFY02922.1 - 7.2e-05 22.6 0.0 0.0022 17.8 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KFY02922.1 - 8.8e-05 23.2 0.0 0.00029 21.5 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KFY02922.1 - 0.00061 20.4 0.0 0.0014 19.2 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.19 KFY02922.1 - 0.031 14.4 0.0 0.074 13.2 0.0 1.6 2 0 0 2 2 2 0 FtsJ-like methyltransferase Methyltransf_4 PF02390.17 KFY02922.1 - 0.053 13.0 0.0 0.12 11.9 0.0 1.5 1 0 0 1 1 1 0 Putative methyltransferase Methyltransf_16 PF10294.9 KFY02922.1 - 0.081 12.6 0.0 0.14 11.8 0.0 1.3 1 0 0 1 1 1 0 Lysine methyltransferase HET PF06985.11 KFY02923.1 - 1.5e-35 122.7 0.7 4.6e-35 121.1 0.2 2.1 2 1 0 2 2 2 1 Heterokaryon incompatibility protein (HET) DUF815 PF05673.13 KFY02923.1 - 0.03 13.5 0.0 0.054 12.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Helo_like_N PF17111.5 KFY02924.1 - 1.2e-154 511.6 32.8 7.9e-75 250.8 5.7 4.2 4 0 0 4 4 4 4 Fungal N-terminal domain of STAND proteins TetR_C_27 PF17935.1 KFY02924.1 - 0.11 12.6 0.5 1.8 8.7 0.0 2.9 3 0 0 3 3 3 0 Tetracyclin repressor-like, C-terminal domain PRESAN PF09687.10 KFY02924.1 - 0.12 12.9 0.0 0.61 10.7 0.0 2.2 2 0 0 2 2 2 0 Plasmodium RESA N-terminal Ku_PK_bind PF08785.11 KFY02924.1 - 0.19 11.9 2.3 2.6 8.2 0.1 3.8 3 1 1 4 4 4 0 Ku C terminal domain like JSRP PF15312.6 KFY02924.1 - 0.31 11.0 1.4 1.2 9.1 0.0 2.7 3 0 0 3 3 3 0 Junctional sarcoplasmic reticulum protein Seryl_tRNA_N PF02403.22 KFY02924.1 - 1.1 9.6 23.4 0.29 11.4 0.2 5.5 5 1 0 5 5 5 0 Seryl-tRNA synthetase N-terminal domain MobL PF18555.1 KFY02924.1 - 1.3 8.2 9.2 0.12 11.6 4.0 1.8 2 0 0 2 2 2 0 MobL relaxases Syntaxin-6_N PF09177.11 KFY02924.1 - 2.7 8.6 23.7 3.4 8.3 0.1 5.9 5 1 1 6 6 6 0 Syntaxin 6, N-terminal MFS_1 PF07690.16 KFY02928.1 - 4.2e-30 104.9 24.5 4.2e-30 104.9 24.5 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF2530 PF10745.9 KFY02928.1 - 0.081 13.2 0.3 0.081 13.2 0.3 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2530) CECR6_TMEM121 PF14997.6 KFY02928.1 - 0.12 12.2 1.4 0.14 12.0 0.1 1.7 2 0 0 2 2 2 0 CECR6/TMEM121 family NEMP PF10225.9 KFY02928.1 - 0.76 9.4 6.6 1.6 8.4 6.6 1.5 1 0 0 1 1 1 0 NEMP family DNA_methylase PF00145.17 KFY02929.1 - 1.4e-30 106.8 0.0 3.1e-30 105.7 0.0 1.6 1 1 0 1 1 1 1 C-5 cytosine-specific DNA methylase Macoilin PF09726.9 KFY02929.1 - 0.42 9.1 5.1 0.071 11.7 1.4 1.5 1 1 1 2 2 2 0 Macoilin family WD40 PF00400.32 KFY02933.1 - 3.3e-34 116.3 3.9 8.9e-10 39.0 0.2 4.0 4 0 0 4 4 3 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFY02933.1 - 2.2e-12 47.1 0.0 0.0012 19.1 0.0 3.5 1 1 2 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain APS_kinase PF01583.20 KFY02933.1 - 9.5e-08 32.1 0.2 0.017 15.0 0.0 2.4 2 0 0 2 2 2 2 Adenylylsulphate kinase AAA_16 PF13191.6 KFY02933.1 - 1.6e-06 28.6 0.7 0.024 15.0 0.0 3.3 3 1 1 4 4 3 2 AAA ATPase domain Ge1_WD40 PF16529.5 KFY02933.1 - 2.6e-05 23.4 0.0 1.4 7.8 0.0 3.1 1 1 2 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein PQQ_3 PF13570.6 KFY02933.1 - 9.5e-05 22.8 4.1 1.2 9.7 0.2 3.4 3 0 0 3 3 3 1 PQQ-like domain NB-ARC PF00931.22 KFY02933.1 - 0.00014 21.1 0.0 0.21 10.7 0.0 2.3 2 0 0 2 2 2 2 NB-ARC domain AAA_30 PF13604.6 KFY02933.1 - 0.00018 21.3 0.0 0.86 9.3 0.0 2.5 2 0 0 2 2 2 2 AAA domain Proteasome_A_N PF10584.9 KFY02933.1 - 0.00042 19.9 0.2 6.4 6.6 0.0 3.6 3 0 0 3 3 3 1 Proteasome subunit A N-terminal signature PQQ_2 PF13360.6 KFY02933.1 - 0.00057 19.6 4.5 0.001 18.7 4.5 1.3 1 0 0 1 1 1 1 PQQ-like domain AAA PF00004.29 KFY02933.1 - 0.001 19.5 0.1 1.3 9.4 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 KFY02933.1 - 0.0012 19.0 0.4 2.8 8.1 0.1 2.8 2 0 0 2 2 2 2 AAA domain NACHT PF05729.12 KFY02933.1 - 0.0029 17.5 0.1 1.4 8.9 0.0 2.7 2 0 0 2 2 2 1 NACHT domain AAA_18 PF13238.6 KFY02933.1 - 0.0038 17.8 3.0 2.7 8.6 0.1 2.9 3 0 0 3 3 2 2 AAA domain AAA_22 PF13401.6 KFY02933.1 - 0.0042 17.4 0.4 4.8 7.5 0.0 2.7 2 0 0 2 2 2 2 AAA domain Cytochrom_D1 PF02239.16 KFY02933.1 - 0.0042 15.7 0.0 0.0079 14.8 0.0 1.4 1 0 0 1 1 1 1 Cytochrome D1 heme domain PD40 PF07676.12 KFY02933.1 - 0.0054 16.6 0.0 33 4.6 0.0 3.7 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat Thymidylate_kin PF02223.17 KFY02933.1 - 0.018 14.8 0.2 5.2 6.7 0.0 2.3 2 0 0 2 2 2 0 Thymidylate kinase PhoH PF02562.16 KFY02933.1 - 0.021 14.3 0.0 7 6.0 0.0 2.2 2 0 0 2 2 2 0 PhoH-like protein RNA_helicase PF00910.22 KFY02933.1 - 0.022 15.1 0.5 12 6.4 0.1 2.6 2 1 0 2 2 2 0 RNA helicase Cytidylate_kin PF02224.18 KFY02933.1 - 0.034 13.9 0.1 11 5.7 0.0 2.3 2 0 0 2 2 2 0 Cytidylate kinase AAA_29 PF13555.6 KFY02933.1 - 0.037 13.8 0.5 16 5.4 0.0 3.1 3 0 0 3 3 3 0 P-loop containing region of AAA domain ParA PF10609.9 KFY02933.1 - 0.099 12.1 0.0 17 4.8 0.0 2.3 2 0 0 2 2 2 0 NUBPL iron-transfer P-loop NTPase AAA_17 PF13207.6 KFY02933.1 - 0.15 12.5 0.1 29 5.1 0.0 2.4 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.27 KFY02933.1 - 0.16 12.5 0.0 36 4.9 0.0 2.5 2 0 0 2 2 2 0 ABC transporter NCOA_u2 PF16665.5 KFY02933.1 - 0.22 11.8 0.3 26 5.2 0.0 2.6 2 1 0 3 3 2 0 Unstructured region on nuclear receptor coactivator protein PEPCK_ATP PF01293.20 KFY02933.1 - 0.27 9.8 0.1 9.7 4.7 0.1 2.1 2 0 0 2 2 2 0 Phosphoenolpyruvate carboxykinase HeLo PF14479.6 KFY02934.1 - 1.7e-43 148.8 0.7 2.1e-43 148.6 0.7 1.1 1 0 0 1 1 1 1 Prion-inhibition and propagation DUF2090 PF09863.9 KFY02934.1 - 0.0037 16.3 0.2 0.005 15.9 0.2 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2090) DUF1192 PF06698.11 KFY02934.1 - 0.015 15.4 0.3 7.2 6.8 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) Vps8 PF12816.7 KFY02939.1 - 3.7e-70 235.5 0.1 1.1e-69 234.0 0.0 1.9 2 0 0 2 2 2 1 Golgi CORVET complex core vacuolar protein 8 Clathrin PF00637.20 KFY02939.1 - 9.7e-07 28.8 0.6 0.071 13.0 0.0 3.7 3 0 0 3 3 3 2 Region in Clathrin and VPS KLRAQ PF10205.9 KFY02940.1 - 0.48 10.7 2.9 0.28 11.4 0.6 1.9 2 1 0 2 2 2 0 Predicted coiled-coil domain-containing protein eIF-3c_N PF05470.12 KFY02942.1 - 6.7 4.9 8.7 0.45 8.8 0.4 2.2 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus COG6 PF06419.11 KFY02943.1 - 1e-225 750.8 13.3 1.1e-225 750.6 13.3 1.0 1 0 0 1 1 1 1 Conserved oligomeric complex COG6 COG2 PF06148.11 KFY02943.1 - 0.0037 17.4 1.1 0.033 14.3 0.3 2.9 2 0 0 2 2 2 1 COG (conserved oligomeric Golgi) complex component, COG2 Abi_C PF14355.6 KFY02943.1 - 0.083 13.0 0.4 0.53 10.4 0.1 2.5 3 0 0 3 3 3 0 Abortive infection C-terminus DASH_Dad4 PF08650.10 KFY02943.1 - 0.087 12.8 0.3 14 5.7 0.1 3.3 3 0 0 3 3 3 0 DASH complex subunit Dad4 Sec23_trunk PF04811.15 KFY02944.1 - 4.4e-70 236.0 0.0 6.3e-70 235.5 0.0 1.2 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.15 KFY02944.1 - 7.1e-23 80.4 0.0 2.6e-22 78.6 0.0 2.0 2 0 0 2 2 2 1 Sec23/Sec24 helical domain Sec23_BS PF08033.12 KFY02944.1 - 4.9e-18 65.7 0.0 9.9e-18 64.7 0.0 1.5 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.15 KFY02944.1 - 1.8e-16 59.9 4.4 3.2e-16 59.1 4.4 1.4 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.22 KFY02944.1 - 5.4e-08 32.6 0.0 1.2e-07 31.5 0.0 1.6 1 0 0 1 1 1 1 Gelsolin repeat Vps36-NZF-N PF16988.5 KFY02944.1 - 0.041 13.3 0.1 0.089 12.2 0.1 1.5 1 0 0 1 1 1 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain Sporozoite_P67 PF05642.11 KFY02944.1 - 2.2 6.3 6.7 3.8 5.5 6.7 1.3 1 0 0 1 1 1 0 Sporozoite P67 surface antigen RAMP4 PF06624.12 KFY02945.1 - 0.0069 16.4 1.8 0.51 10.4 0.3 2.2 2 0 0 2 2 2 2 Ribosome associated membrane protein RAMP4 TMEMspv1-c74-12 PF11044.8 KFY02945.1 - 0.039 14.0 0.2 0.065 13.2 0.2 1.5 1 1 0 1 1 1 0 Plectrovirus spv1-c74 ORF 12 transmembrane protein Fungal_trans_2 PF11951.8 KFY02946.1 - 2.1e-15 56.5 0.3 9e-15 54.4 0.0 1.9 1 1 1 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KFY02946.1 - 1.6e-05 24.9 9.7 2.7e-05 24.2 9.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain FAM70 PF14967.6 KFY02946.1 - 2.8 7.3 11.9 1 8.8 4.9 2.2 2 0 0 2 2 2 0 FAM70 protein WD40 PF00400.32 KFY02947.1 - 0.0037 18.1 1.2 3.1 8.8 0.0 4.8 5 0 0 5 5 5 1 WD domain, G-beta repeat LCAT PF02450.15 KFY02948.1 - 1.9e-104 350.0 0.0 2.5e-104 349.6 0.0 1.1 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase DUF1917 PF08939.10 KFY02948.1 - 1.3e-67 228.5 0.0 1.9e-67 228.0 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1917) Abhydrolase_6 PF12697.7 KFY02948.1 - 0.00047 20.8 0.0 0.0015 19.1 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Sld5 PF05916.11 KFY02949.1 - 1e-15 58.1 0.0 1.7e-15 57.4 0.0 1.4 1 0 0 1 1 1 1 GINS complex protein PHD PF00628.29 KFY02949.1 - 2.2e-09 37.0 8.0 3.8e-09 36.3 8.0 1.4 1 0 0 1 1 1 1 PHD-finger zf-PHD-like PF15446.6 KFY02949.1 - 0.0063 16.2 3.4 0.015 14.9 3.4 1.6 1 0 0 1 1 1 1 PHD/FYVE-zinc-finger like domain PHD_2 PF13831.6 KFY02949.1 - 0.014 15.0 5.3 0.014 15.0 5.3 2.2 2 1 0 2 2 2 0 PHD-finger zf-RRPl_C4 PF17026.5 KFY02949.1 - 0.1 12.7 1.9 0.18 11.9 1.9 1.3 1 0 0 1 1 1 0 Putative ribonucleoprotein zinc-finger pf C4 type ORC6 PF05460.13 KFY02949.1 - 0.36 10.0 7.5 0.64 9.2 7.5 1.3 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) C1_1 PF00130.22 KFY02949.1 - 0.69 9.9 7.4 0.11 12.4 2.8 1.9 1 1 1 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Sod_Fe_C PF02777.18 KFY02950.1 - 1.9e-35 121.1 1.8 2.6e-35 120.7 0.5 1.8 2 0 0 2 2 2 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.22 KFY02950.1 - 5.5e-29 100.5 2.3 9e-29 99.8 2.3 1.3 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, alpha-hairpin domain ChaB PF06150.12 KFY02950.1 - 0.019 15.5 0.7 0.06 13.9 0.7 1.8 1 0 0 1 1 1 0 ChaB RabGAP-TBC PF00566.18 KFY02951.1 - 5.8e-35 120.9 0.0 7.2e-32 110.8 0.0 2.5 2 1 0 2 2 2 2 Rab-GTPase-TBC domain Ribonucleas_3_3 PF14622.6 KFY02952.1 - 6.7e-11 42.4 0.0 8.4e-11 42.1 0.0 1.2 1 0 0 1 1 1 1 Ribonuclease-III-like Ribonuclease_3 PF00636.26 KFY02952.1 - 1e-10 42.2 0.0 2.6e-10 40.9 0.0 1.6 1 1 0 1 1 1 1 Ribonuclease III domain Plasmod_dom_1 PF09715.10 KFY02952.1 - 0.15 12.2 0.0 0.27 11.3 0.0 1.4 1 0 0 1 1 1 0 Plasmodium protein of unknown function (Plasmod_dom_1) Beta-lactamase PF00144.24 KFY02953.1 - 1.1e-39 136.7 0.0 1.4e-33 116.5 0.0 2.2 2 0 0 2 2 2 2 Beta-lactamase DUF3471 PF11954.8 KFY02953.1 - 2.2e-12 47.4 0.0 3.9e-12 46.6 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3471) PAF-AH_p_II PF03403.13 KFY02954.1 - 2.2e-15 56.1 0.0 6e-07 28.3 0.0 2.1 2 0 0 2 2 2 2 Platelet-activating factor acetylhydrolase, isoform II Chlorophyllase2 PF12740.7 KFY02954.1 - 6.1e-08 31.9 0.0 1.6e-07 30.5 0.0 1.7 2 1 0 2 2 2 1 Chlorophyllase enzyme Abhydrolase_5 PF12695.7 KFY02954.1 - 0.00068 19.4 0.2 0.47 10.2 0.0 2.4 2 0 0 2 2 2 2 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KFY02954.1 - 0.00082 18.7 0.1 0.014 14.6 0.1 2.1 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Chlorophyllase PF07224.11 KFY02954.1 - 0.011 14.8 1.7 0.083 11.9 0.5 2.3 2 1 0 2 2 2 0 Chlorophyllase Abhydrolase_6 PF12697.7 KFY02954.1 - 0.012 16.3 0.1 0.019 15.5 0.1 1.5 1 1 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KFY02954.1 - 0.063 12.9 0.0 0.11 12.1 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold Lipase_3 PF01764.25 KFY02954.1 - 0.19 11.6 0.0 0.39 10.6 0.0 1.5 1 0 0 1 1 1 0 Lipase (class 3) Fungal_trans_2 PF11951.8 KFY02955.1 - 6.2e-20 71.4 0.0 1.1e-19 70.5 0.0 1.3 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KFY02955.1 - 3.1e-05 24.0 11.0 5.2e-05 23.3 11.0 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SIMPL PF04402.14 KFY02956.1 - 2.1e-25 90.3 4.0 2.6e-25 90.1 4.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF541) adh_short PF00106.25 KFY02958.1 - 7.3e-21 74.5 0.0 2.9e-18 66.0 0.0 2.2 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KFY02958.1 - 5.3e-13 49.1 0.0 5.7e-12 45.7 0.0 2.1 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KFY02958.1 - 5.3e-07 29.7 0.0 2.5e-06 27.5 0.0 1.8 2 0 0 2 2 2 1 KR domain Epimerase PF01370.21 KFY02958.1 - 0.0017 17.9 0.0 0.0063 16.0 0.0 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KFY02958.1 - 0.0033 16.9 0.0 0.015 14.7 0.0 1.8 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase THF_DHG_CYH_C PF02882.19 KFY02958.1 - 0.082 12.2 0.0 0.15 11.4 0.0 1.3 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Glyco_hydro_16 PF00722.21 KFY02959.1 - 9.2e-18 64.3 0.1 1.5e-17 63.6 0.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Cnn_1N PF07989.11 KFY02960.1 - 0.031 14.4 8.0 0.73 10.0 6.0 2.9 1 1 1 2 2 2 0 Centrosomin N-terminal motif 1 DUF1454 PF07305.12 KFY02960.1 - 0.031 13.7 0.2 0.11 11.9 0.1 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1454) Attacin_N PF03768.15 KFY02960.1 - 0.17 12.0 4.3 1.8 8.8 1.9 2.7 2 0 0 2 2 2 0 Attacin, N-terminal region JIP_LZII PF16471.5 KFY02960.1 - 8.1 6.7 9.3 21 5.3 0.1 3.3 2 1 0 2 2 2 0 JNK-interacting protein leucine zipper II Apc15p PF05841.11 KFY02962.1 - 0.33 11.8 4.7 0.37 11.6 4.7 1.1 1 0 0 1 1 1 0 Apc15p protein Pectate_lyase PF03211.13 KFY02963.1 - 4.9e-77 258.1 7.8 5.9e-77 257.8 7.8 1.1 1 0 0 1 1 1 1 Pectate lyase OPT PF03169.15 KFY02964.1 - 8.7e-119 397.9 46.9 3.2e-118 396.0 46.9 1.7 1 1 0 1 1 1 1 OPT oligopeptide transporter protein DUF4191 PF13829.6 KFY02964.1 - 0.24 10.7 0.3 0.49 9.7 0.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4191) DUF3237 PF11578.8 KFY02965.1 - 1.3e-06 28.3 0.1 1.7e-06 28.0 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3237) FAD_binding_4 PF01565.23 KFY02966.1 - 7.5e-21 74.3 2.9 1.6e-20 73.3 2.9 1.6 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 KFY02966.1 - 3.2e-06 27.1 0.0 7.2e-06 26.0 0.0 1.6 1 0 0 1 1 1 1 Berberine and berberine like HATPase_c PF02518.26 KFY02968.1 - 5e-20 72.1 0.1 1.1e-19 70.9 0.1 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 KFY02968.1 - 2.1e-17 63.3 0.1 3.4e-12 46.5 0.0 3.7 4 0 0 4 4 4 2 Response regulator receiver domain HisKA PF00512.25 KFY02968.1 - 2.2e-12 46.8 0.0 5.6e-12 45.5 0.0 1.7 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain GAF_2 PF13185.6 KFY02968.1 - 0.0026 18.1 0.1 0.0075 16.6 0.0 1.9 2 0 0 2 2 2 1 GAF domain Grg1 PF11034.8 KFY02969.1 - 1.8e-32 111.4 12.5 2e-32 111.2 12.5 1.0 1 0 0 1 1 1 1 Glucose-repressible protein Grg1 MFS_1 PF07690.16 KFY02970.1 - 6.1e-27 94.5 19.1 4.1e-26 91.8 16.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily OAD_gamma PF04277.13 KFY02970.1 - 0.012 16.2 0.0 0.03 14.9 0.0 1.7 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain Phage_holin_3_6 PF07332.11 KFY02970.1 - 0.25 11.4 2.9 24 5.0 1.5 2.5 2 0 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III Glyco_hydro_88 PF07470.13 KFY02971.1 - 1.7e-10 40.5 0.0 3.6e-10 39.4 0.0 1.4 1 1 0 1 1 1 1 Glycosyl Hydrolase Family 88 Gemini_AL1_M PF08283.11 KFY02971.1 - 0.057 13.5 0.0 0.12 12.5 0.0 1.4 1 0 0 1 1 1 0 Geminivirus rep protein central domain Fungal_trans PF04082.18 KFY02972.1 - 2.7e-15 56.1 0.1 5e-15 55.2 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KFY02972.1 - 9.7e-07 28.8 10.4 2e-06 27.8 10.4 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Clusterin PF01093.17 KFY02972.1 - 0.15 11.1 4.5 0.23 10.4 4.5 1.3 1 0 0 1 1 1 0 Clusterin DUF2264 PF10022.9 KFY02973.1 - 6.1e-127 423.5 0.1 7.8e-127 423.2 0.1 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2264) Beta-lactamase PF00144.24 KFY02975.1 - 2.9e-24 85.9 0.2 4.2e-24 85.4 0.2 1.2 1 0 0 1 1 1 1 Beta-lactamase Glyco_hydro_1 PF00232.18 KFY02976.1 - 1.3e-77 261.2 0.7 1.2e-75 254.7 0.7 2.4 1 1 0 1 1 1 1 Glycosyl hydrolase family 1 Fungal_trans_2 PF11951.8 KFY02976.1 - 8.5e-35 120.3 0.4 1.7e-34 119.3 0.4 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KFY02976.1 - 4.9e-09 36.2 5.1 4.9e-09 36.2 5.1 2.3 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ERG4_ERG24 PF01222.17 KFY02977.1 - 1.1e-146 489.0 20.2 1.2e-146 488.8 20.2 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family 2-Hacid_dh_C PF02826.19 KFY02981.1 - 1.9e-35 121.9 0.0 1e-22 80.4 0.0 2.2 2 0 0 2 2 2 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain IlvN PF07991.12 KFY02981.1 - 0.021 14.4 0.0 0.036 13.6 0.0 1.2 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain F420_oxidored PF03807.17 KFY02981.1 - 0.13 12.9 0.0 0.23 12.1 0.0 1.5 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent 3HCDH_N PF02737.18 KFY02981.1 - 0.17 11.7 0.0 0.29 11.0 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Lipase_GDSL_2 PF13472.6 KFY02982.1 - 7.1e-23 81.9 0.0 8.6e-23 81.7 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 KFY02982.1 - 1.5e-09 38.2 0.0 3.1e-09 37.1 0.0 1.6 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_3 PF14606.6 KFY02982.1 - 6.5e-08 32.9 0.0 1.9e-06 28.2 0.0 2.6 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family HTH_Tnp_Tc3_2 PF01498.18 KFY02982.1 - 0.16 12.2 0.0 0.29 11.4 0.0 1.5 1 0 0 1 1 1 0 Transposase Pribosyltran PF00156.27 KFY02983.1 - 9e-07 28.5 0.0 1.5e-06 27.8 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UQ_con PF00179.26 KFY02985.1 - 6.9e-20 71.1 0.1 9.6e-20 70.7 0.1 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Bac_surface_Ag PF01103.23 KFY02986.1 - 7e-47 160.5 0.8 8.8e-47 160.2 0.8 1.1 1 0 0 1 1 1 1 Surface antigen EBP PF05241.12 KFY02987.1 - 3.1e-60 202.7 7.8 3.8e-60 202.4 7.8 1.1 1 0 0 1 1 1 1 Emopamil binding protein ANAPC4_WD40 PF12894.7 KFY02988.1 - 3.9e-08 33.5 0.0 0.3 11.4 0.0 4.3 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain IKI3 PF04762.12 KFY02988.1 - 2.1e-06 26.1 0.0 4e-05 21.8 0.0 2.1 2 0 0 2 2 2 1 IKI3 family WD40 PF00400.32 KFY02988.1 - 0.00023 21.9 5.8 3.3 8.7 0.0 5.6 6 0 0 6 6 6 2 WD domain, G-beta repeat PD40 PF07676.12 KFY02988.1 - 0.12 12.3 0.0 0.12 12.3 0.0 3.2 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat MoaC PF01967.21 KFY02989.1 - 4.1e-52 175.9 0.2 7e-52 175.1 0.2 1.4 1 0 0 1 1 1 1 MoaC family Mob_synth_C PF06463.13 KFY02989.1 - 1.3e-35 122.2 0.0 4.2e-35 120.5 0.0 1.8 1 1 1 2 2 2 1 Molybdenum Cofactor Synthesis C Radical_SAM PF04055.21 KFY02989.1 - 4.9e-27 95.3 0.0 1.1e-26 94.2 0.0 1.6 1 0 0 1 1 1 1 Radical SAM superfamily Fer4_12 PF13353.6 KFY02989.1 - 0.00089 19.5 0.0 0.003 17.8 0.0 1.9 1 0 0 1 1 1 1 4Fe-4S single cluster domain Rep_4 PF05797.11 KFY02990.1 - 0.079 12.1 0.4 0.12 11.5 0.4 1.1 1 0 0 1 1 1 0 Yeast trans-acting factor (REP1/REP2) EHN PF06441.12 KFY02991.1 - 9.9e-36 122.4 1.1 8.6e-35 119.4 0.1 2.2 2 0 0 2 2 2 1 Epoxide hydrolase N terminus Abhydrolase_1 PF00561.20 KFY02991.1 - 5.9e-12 45.8 0.0 1.1e-11 44.9 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KFY02991.1 - 4.5e-06 27.4 2.9 1.3e-05 25.9 2.9 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family stn_TNFRSF12A PF12191.8 KFY02992.1 - 0.028 14.6 0.1 0.061 13.5 0.1 1.5 1 0 0 1 1 1 0 Tumour necrosis factor receptor stn_TNFRSF12A_TNFR domain Methyltransf_28 PF02636.17 KFY02993.1 - 2.6e-81 273.1 0.0 3.2e-81 272.8 0.0 1.1 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Pkinase PF00069.25 KFY02994.1 - 2e-60 204.4 0.0 2.8e-60 203.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFY02994.1 - 1.1e-27 97.0 0.0 1.5e-27 96.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 KFY02994.1 - 0.00012 21.6 0.0 0.00028 20.3 0.0 1.6 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 KFY02994.1 - 0.012 14.6 0.0 0.016 14.2 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain DUF3621 PF12285.8 KFY02994.1 - 0.12 12.7 0.3 0.12 12.7 0.3 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3621) APH PF01636.23 KFY02994.1 - 0.24 11.3 0.0 0.24 11.3 0.0 2.2 2 0 0 2 2 2 0 Phosphotransferase enzyme family eIF3_subunit PF08597.10 KFY02994.1 - 1.1 9.1 16.2 1.6 8.6 16.2 1.2 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit DUF4661 PF15576.6 KFY02994.1 - 1.6 8.6 4.7 2.5 8.0 4.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4661) RNA_pol_Rpc4 PF05132.14 KFY02995.1 - 0.021 15.2 1.0 0.032 14.7 1.0 1.2 1 0 0 1 1 1 0 RNA polymerase III RPC4 DAHP_synth_1 PF00793.20 KFY02997.1 - 2.2e-101 338.3 0.1 2.6e-101 338.1 0.1 1.0 1 0 0 1 1 1 1 DAHP synthetase I family Myb_DNA-bind_6 PF13921.6 KFY03012.1 - 0.0028 17.8 0.7 0.0065 16.7 0.7 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 KFY03012.1 - 0.017 15.3 0.1 0.035 14.3 0.1 1.5 1 0 0 1 1 1 0 Myb-like DNA-binding domain Fungal_trans_2 PF11951.8 KFY03013.1 - 2.9e-19 69.1 2.8 7.5e-19 67.8 2.8 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain Abhydro_lipase PF04083.16 KFY03013.1 - 0.031 13.9 0.0 0.087 12.4 0.0 1.7 1 0 0 1 1 1 0 Partial alpha/beta-hydrolase lipase region Methyltr_RsmB-F PF01189.17 KFY03014.1 - 1.1e-79 266.7 0.0 2.1e-79 265.8 0.0 1.4 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F Methyltr_RsmF_N PF17125.5 KFY03014.1 - 1.6e-07 31.7 0.0 5.8e-07 29.9 0.0 2.0 1 0 0 1 1 1 1 N-terminal domain of 16S rRNA methyltransferase RsmF DUF2431 PF10354.9 KFY03014.1 - 0.024 14.9 0.0 0.049 13.9 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF2431) Blt1 PF12754.7 KFY03015.1 - 3.7e-35 121.5 0.0 5e-35 121.0 0.0 1.2 1 0 0 1 1 1 1 Blt1 N-terminal domain Blt1_C PF17183.4 KFY03015.1 - 1.2e-20 72.8 0.6 2e-20 72.1 0.6 1.4 1 0 0 1 1 1 1 Get5 carboxyl domain Cpn60_TCP1 PF00118.24 KFY03016.1 - 1.4e-83 281.2 11.6 2.6e-83 280.3 11.6 1.4 1 1 0 1 1 1 1 TCP-1/cpn60 chaperonin family Cofilin_ADF PF00241.20 KFY03016.1 - 4.8e-38 129.7 0.1 9.5e-38 128.7 0.1 1.5 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein Med3 PF11593.8 KFY03020.1 - 0.16 11.2 3.7 0.17 11.0 3.7 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Med3 PF11593.8 KFY03021.1 - 0.58 9.3 6.9 0.85 8.7 6.9 1.3 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Lipase_GDSL PF00657.22 KFY03046.1 - 1e-10 41.9 0.0 1.7e-10 41.3 0.0 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.6 KFY03046.1 - 0.00025 21.5 1.8 0.00075 19.9 1.8 2.1 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family MFS_1 PF07690.16 KFY03048.1 - 2e-33 115.8 33.2 2e-33 115.8 33.2 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Phage_holin_5_2 PF16079.5 KFY03048.1 - 0.2 12.0 0.1 0.2 12.0 0.1 3.5 2 1 1 3 3 3 0 Phage holin family Hol44, in holin superfamily V Septin PF00735.18 KFY03049.1 - 2e-119 398.0 0.0 2e-119 398.0 0.0 1.8 2 0 0 2 2 2 1 Septin MMR_HSR1 PF01926.23 KFY03049.1 - 4.1e-08 33.3 0.7 1.1e-07 32.0 0.0 2.0 2 0 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 KFY03049.1 - 6.2e-05 22.6 1.7 0.0029 17.2 0.0 3.0 2 2 0 2 2 2 1 Elongation factor Tu GTP binding domain ABC_tran PF00005.27 KFY03049.1 - 7e-05 23.4 1.0 0.028 14.9 0.0 2.5 2 0 0 2 2 2 1 ABC transporter AAA_16 PF13191.6 KFY03049.1 - 0.0014 19.0 0.1 0.0046 17.3 0.0 1.9 2 0 0 2 2 2 1 AAA ATPase domain AIG1 PF04548.16 KFY03049.1 - 0.0018 17.6 1.3 0.0058 16.0 0.0 2.3 2 0 0 2 2 2 1 AIG1 family Roc PF08477.13 KFY03049.1 - 0.0036 17.5 0.0 0.0079 16.4 0.0 1.6 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase RsgA_GTPase PF03193.16 KFY03049.1 - 0.0039 17.1 1.2 0.0039 17.1 1.2 3.4 3 1 0 3 3 2 1 RsgA GTPase Ras PF00071.22 KFY03049.1 - 0.0091 15.6 1.1 0.039 13.6 0.0 2.5 3 1 0 3 3 3 1 Ras family AAA_29 PF13555.6 KFY03049.1 - 0.017 14.9 0.0 0.031 14.0 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_22 PF13401.6 KFY03049.1 - 0.026 14.8 2.4 0.033 14.4 0.1 2.4 2 2 0 2 2 2 0 AAA domain FtsK_SpoIIIE PF01580.18 KFY03049.1 - 0.045 13.1 0.0 0.12 11.7 0.0 1.7 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_24 PF13479.6 KFY03049.1 - 0.061 13.0 0.0 0.13 12.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 KFY03049.1 - 0.074 13.4 0.4 0.79 10.1 0.0 2.4 2 0 0 2 2 2 0 RNA helicase ATP_bind_1 PF03029.17 KFY03049.1 - 0.076 12.8 2.7 3.5 7.3 0.0 3.2 3 1 0 3 3 3 0 Conserved hypothetical ATP binding protein Exonuc_VII_L PF02601.15 KFY03049.1 - 0.091 12.3 5.4 0.14 11.7 5.4 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit AAA_7 PF12775.7 KFY03049.1 - 0.099 12.1 0.0 0.21 11.1 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region Dynamin_N PF00350.23 KFY03049.1 - 0.14 12.2 8.6 0.89 9.6 0.0 3.5 3 1 0 3 3 2 0 Dynamin family DUF3987 PF13148.6 KFY03049.1 - 1.7 7.6 0.0 1.7 7.6 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3987) DUF87 PF01935.17 KFY03049.1 - 2.4 8.2 7.0 4.5 7.3 0.0 2.6 3 0 0 3 3 2 0 Helicase HerA, central domain Atg14 PF10186.9 KFY03049.1 - 4.7 6.2 9.5 7 5.6 9.5 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 UPF0242 PF06785.11 KFY03049.1 - 5.3 7.1 14.2 9.1 6.3 14.2 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Strep_SA_rep PF06696.11 KFY03049.1 - 6.5 6.9 7.0 2.5 8.2 3.6 2.1 1 1 1 2 2 2 0 Streptococcal surface antigen repeat Clat_adaptor_s PF01217.20 KFY03050.1 - 1.8e-54 183.5 1.2 4.2e-54 182.3 1.2 1.6 1 0 0 1 1 1 1 Clathrin adaptor complex small chain PDZ_1 PF12812.7 KFY03050.1 - 6.4e-53 176.7 0.0 9.4e-35 118.5 0.0 2.5 2 0 0 2 2 2 2 PDZ-like domain Trypsin_2 PF13365.6 KFY03050.1 - 1.8e-27 97.0 1.5 1.1e-21 78.2 0.1 2.5 2 0 0 2 2 2 2 Trypsin-like peptidase domain PDZ_6 PF17820.1 KFY03050.1 - 5.5e-13 48.6 0.4 4.5e-05 23.2 0.1 3.8 3 0 0 3 3 3 3 PDZ domain PDZ_2 PF13180.6 KFY03050.1 - 7e-12 45.5 0.1 0.00052 20.3 0.0 4.5 4 0 0 4 4 4 3 PDZ domain PDZ PF00595.24 KFY03050.1 - 4.4e-10 39.8 0.0 0.00044 20.5 0.0 3.8 3 0 0 3 3 3 2 PDZ domain Trypsin PF00089.26 KFY03050.1 - 6.4e-05 22.9 0.0 0.00016 21.6 0.0 1.6 1 0 0 1 1 1 1 Trypsin Tricorn_PDZ PF14685.6 KFY03050.1 - 0.037 14.0 0.9 5.7 7.0 0.1 3.4 3 0 0 3 3 3 0 Tricorn protease PDZ domain 4HPAD_g_N PF18671.1 KFY03050.1 - 0.078 12.7 0.0 0.23 11.2 0.0 1.8 1 0 0 1 1 1 0 4-Hydroxyphenylacetate decarboxylase subunit gamma N-terminal ArAE_2_N PF10337.9 KFY03051.1 - 7.5e-27 94.5 6.7 3.5e-16 59.3 0.0 3.1 1 1 1 2 2 2 2 Putative ER transporter, 6TM, N-terminal FUSC_2 PF13515.6 KFY03051.1 - 3.9e-09 36.7 19.3 3.9e-09 36.7 19.3 3.1 2 1 0 2 2 2 1 Fusaric acid resistance protein-like ALMT PF11744.8 KFY03051.1 - 9.1e-06 24.8 9.9 9.1e-06 24.8 9.9 4.3 4 0 0 4 4 4 3 Aluminium activated malate transporter ArAE_2 PF10334.9 KFY03051.1 - 0.00041 20.2 0.0 0.0008 19.3 0.0 1.5 1 0 0 1 1 1 1 Aromatic acid exporter family member 2 EURL PF06937.11 KFY03051.1 - 4.7 6.5 9.9 0.37 10.2 1.9 2.2 2 0 0 2 2 2 0 EURL protein Ist1 PF03398.14 KFY03052.1 - 6.2e-61 205.1 3.8 8e-61 204.7 3.8 1.1 1 0 0 1 1 1 1 Regulator of Vps4 activity in the MVB pathway Cupin_4 PF08007.12 KFY03053.1 - 0.11 12.0 0.0 0.19 11.2 0.0 1.3 1 0 0 1 1 1 0 Cupin superfamily protein GATA PF00320.27 KFY03053.1 - 0.73 9.5 17.3 0.024 14.3 4.1 3.2 2 0 0 2 2 2 0 GATA zinc finger DNA_topoisoIV PF00521.20 KFY03054.1 - 2e-123 412.5 0.0 6.9e-123 410.7 0.0 1.8 2 0 0 2 2 2 1 DNA gyrase/topoisomerase IV, subunit A TOPRIM_C PF16898.5 KFY03054.1 - 1.6e-48 164.2 2.8 6e-48 162.3 2.8 2.1 1 0 0 1 1 1 1 C-terminal associated domain of TOPRIM DNA_gyraseB PF00204.25 KFY03054.1 - 2.3e-25 89.0 4.1 6.2e-25 87.7 4.1 1.7 1 0 0 1 1 1 1 DNA gyrase B HATPase_c PF02518.26 KFY03054.1 - 8.2e-14 52.1 0.2 2.9e-13 50.3 0.0 2.1 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Toprim PF01751.22 KFY03054.1 - 5.2e-06 26.6 0.0 2.2e-05 24.6 0.0 2.2 1 0 0 1 1 1 1 Toprim domain DUF4354 PF14263.6 KFY03054.1 - 0.033 14.0 1.0 0.4 10.5 0.0 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4354) Glyco_hydro_65C PF03633.15 KFY03054.1 - 0.071 13.0 0.1 0.17 11.8 0.1 1.6 1 0 0 1 1 1 0 Glycosyl hydrolase family 65, C-terminal domain DUF4441 PF14536.6 KFY03054.1 - 0.082 13.1 0.8 0.43 10.8 0.8 2.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4441) Dynamin_N PF00350.23 KFY03056.1 - 1.2e-06 28.7 0.7 4e-06 27.0 0.0 2.3 2 1 0 2 2 2 1 Dynamin family RsgA_GTPase PF03193.16 KFY03056.1 - 0.00046 20.1 0.1 0.0025 17.7 0.0 2.2 2 0 0 2 2 2 1 RsgA GTPase ABC_tran PF00005.27 KFY03056.1 - 0.0011 19.5 0.0 0.0059 17.1 0.0 2.3 2 0 0 2 2 2 1 ABC transporter MMR_HSR1 PF01926.23 KFY03056.1 - 0.0017 18.4 0.0 0.0099 16.0 0.0 2.3 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_16 PF13191.6 KFY03056.1 - 0.0018 18.7 0.6 0.02 15.3 0.1 2.9 3 1 0 3 3 3 1 AAA ATPase domain IIGP PF05049.13 KFY03056.1 - 0.0047 16.0 0.0 0.014 14.5 0.0 1.8 1 0 0 1 1 1 1 Interferon-inducible GTPase (IIGP) Roc PF08477.13 KFY03056.1 - 0.063 13.5 0.1 0.67 10.2 0.1 2.6 2 1 1 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase GTP_EFTU PF00009.27 KFY03056.1 - 0.078 12.5 0.2 0.64 9.5 0.1 2.5 3 0 0 3 3 3 0 Elongation factor Tu GTP binding domain AAA_29 PF13555.6 KFY03056.1 - 0.089 12.5 0.0 0.25 11.1 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain SMC_N PF02463.19 KFY03056.1 - 0.13 11.7 0.0 0.31 10.5 0.0 1.5 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain TPR_1 PF00515.28 KFY03057.1 - 5.4e-08 32.3 0.5 0.27 11.1 0.0 4.1 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.17 KFY03057.1 - 3.9e-07 29.7 0.2 0.34 11.1 0.0 4.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 KFY03057.1 - 0.019 15.1 1.8 26 5.4 0.0 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat Glyco_transf_17 PF04724.13 KFY03057.1 - 0.096 11.7 0.0 0.15 11.1 0.0 1.2 1 0 0 1 1 1 0 Glycosyltransferase family 17 TPR_11 PF13414.6 KFY03057.1 - 0.16 11.7 0.2 0.91 9.3 0.0 2.4 3 0 0 3 3 3 0 TPR repeat ANAPC3 PF12895.7 KFY03057.1 - 0.22 11.8 1.7 0.31 11.3 0.5 1.9 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 PPR_2 PF13041.6 KFY03058.1 - 1.8e-15 56.9 0.7 0.25 11.5 0.0 8.1 6 3 3 9 9 9 4 PPR repeat family PPR_3 PF13812.6 KFY03058.1 - 4e-15 55.6 0.0 0.007 16.4 0.0 6.5 4 2 3 7 7 7 6 Pentatricopeptide repeat domain PPR_long PF17177.4 KFY03058.1 - 1.6e-09 37.5 0.1 0.061 12.7 0.0 4.4 4 1 1 5 5 5 3 Pentacotripeptide-repeat region of PRORP PPR PF01535.20 KFY03058.1 - 8.7e-08 31.9 14.6 6.6 7.2 0.2 7.3 8 0 0 8 8 8 4 PPR repeat PPR_1 PF12854.7 KFY03058.1 - 0.0079 15.9 0.0 73 3.2 0.0 5.4 6 0 0 6 6 6 0 PPR repeat TPR_14 PF13428.6 KFY03058.1 - 0.026 15.3 9.3 18 6.5 0.2 5.8 6 1 0 6 6 6 0 Tetratricopeptide repeat TPR_7 PF13176.6 KFY03058.1 - 0.041 13.9 0.2 0.54 10.4 0.1 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat Sigma70_ner PF04546.13 KFY03058.1 - 0.14 12.0 0.1 0.27 11.1 0.1 1.5 1 0 0 1 1 1 0 Sigma-70, non-essential region LSM PF01423.22 KFY03059.1 - 1.1e-16 60.3 0.0 1.4e-16 59.9 0.0 1.2 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 KFY03059.1 - 0.0022 18.1 0.0 0.0034 17.5 0.0 1.3 1 0 0 1 1 1 1 Ataxin 2 SM domain FeoB_associated PF12669.7 KFY03060.1 - 0.007 16.7 1.3 0.021 15.2 1.3 1.8 1 0 0 1 1 1 1 FeoB-associated Cys-rich membrane protein Collagen PF01391.18 KFY03060.1 - 0.12 12.1 0.5 0.32 10.8 0.5 1.6 1 0 0 1 1 1 0 Collagen triple helix repeat (20 copies) Glyco_hydro_7 PF00840.20 KFY03061.1 - 5e-194 645.0 12.0 5.6e-194 644.8 12.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 7 DUF2986 PF11661.8 KFY03062.1 - 0.044 14.3 0.6 0.084 13.4 0.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2986) Ammonium_transp PF00909.21 KFY03074.1 - 1.1e-80 271.3 21.2 1.3e-80 271.1 21.2 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family CRT10 PF08728.10 KFY03076.1 - 9.3e-17 60.5 0.0 9.6e-09 34.0 0.0 2.3 2 0 0 2 2 2 2 CRT10 PBP1_TM PF14812.6 KFY03076.1 - 3.5 8.1 9.5 14 6.2 9.5 2.0 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Cellulase PF00150.18 KFY03078.1 - 6e-12 45.6 0.0 8.2e-12 45.1 0.0 1.2 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Git3 PF11710.8 KFY03082.1 - 7.6e-05 22.6 1.3 9e-05 22.3 1.3 1.0 1 0 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 WD40 PF00400.32 KFY03084.1 - 0 997.1 143.7 2.8e-10 40.6 0.5 32.8 32 0 0 32 32 32 31 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFY03084.1 - 1.5e-90 297.7 57.9 0.00027 21.1 0.1 30.3 3 2 28 31 31 31 29 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KFY03084.1 - 6.4e-24 84.5 98.8 0.32 9.6 0.2 24.9 4 4 23 28 28 28 15 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.16 KFY03084.1 - 5.8e-22 77.7 44.9 0.00014 20.5 0.1 12.0 3 3 9 14 14 14 12 Cytochrome D1 heme domain Ge1_WD40 PF16529.5 KFY03084.1 - 4e-21 75.3 67.9 1.5 7.7 0.1 24.5 3 2 15 24 24 24 6 WD40 region of Ge1, enhancer of mRNA-decapping protein Frtz PF11768.8 KFY03084.1 - 5e-21 74.6 18.0 0.6 8.4 0.0 15.6 4 3 17 23 23 23 5 WD repeat-containing and planar cell polarity effector protein Fritz NACHT PF05729.12 KFY03084.1 - 3.4e-18 66.1 0.2 1.2e-08 35.1 0.0 2.6 2 0 0 2 2 2 2 NACHT domain AAA_16 PF13191.6 KFY03084.1 - 1.4e-14 54.9 1.1 1.4e-06 28.8 0.1 3.3 2 0 0 2 2 2 2 AAA ATPase domain WD40_like PF17005.5 KFY03084.1 - 1.6e-13 50.6 9.4 11 5.3 0.2 12.7 7 3 6 18 18 17 0 WD40-like domain Nbas_N PF15492.6 KFY03084.1 - 2.3e-06 27.2 50.8 8.5 5.6 0.2 16.8 2 1 11 16 16 16 0 Neuroblastoma-amplified sequence, N terminal Helo_like_N PF17111.5 KFY03084.1 - 8.3e-06 25.3 0.4 2.3e-05 23.9 0.4 1.7 1 0 0 1 1 1 1 Fungal N-terminal domain of STAND proteins APS_kinase PF01583.20 KFY03084.1 - 1.1e-05 25.4 0.2 0.072 13.0 0.0 2.6 2 0 0 2 2 2 2 Adenylylsulphate kinase Proteasome_A_N PF10584.9 KFY03084.1 - 1.8e-05 24.3 10.2 74 3.2 0.1 9.5 9 0 0 9 9 9 0 Proteasome subunit A N-terminal signature PD40 PF07676.12 KFY03084.1 - 2.6e-05 24.0 14.1 83 3.3 0.1 13.2 16 0 0 16 16 12 0 WD40-like Beta Propeller Repeat AAA_18 PF13238.6 KFY03084.1 - 7.3e-05 23.3 0.0 1.2 9.7 0.0 3.5 2 0 0 2 2 2 2 AAA domain AAA_30 PF13604.6 KFY03084.1 - 0.0001 22.1 0.3 0.13 12.0 0.1 2.7 2 0 0 2 2 2 2 AAA domain Dak2 PF02734.17 KFY03084.1 - 0.00018 21.5 32.5 2.3 8.1 0.1 9.9 4 3 5 10 10 10 1 DAK2 domain NB-ARC PF00931.22 KFY03084.1 - 0.00058 19.1 0.0 0.71 9.0 0.0 2.8 2 0 0 2 2 2 2 NB-ARC domain WXG100 PF06013.12 KFY03084.1 - 0.0018 18.5 25.0 1.7e+02 2.5 0.0 13.8 17 0 0 17 17 15 0 Proteins of 100 residues with WXG KAP_NTPase PF07693.14 KFY03084.1 - 0.0018 17.6 0.8 0.49 9.6 0.0 2.6 2 0 0 2 2 2 1 KAP family P-loop domain PQQ_3 PF13570.6 KFY03084.1 - 0.0021 18.5 19.4 7.9 7.1 0.1 11.5 13 0 0 13 13 12 0 PQQ-like domain AAA_22 PF13401.6 KFY03084.1 - 0.0022 18.3 0.0 4.3 7.6 0.0 2.7 2 0 0 2 2 2 2 AAA domain Jnk-SapK_ap_N PF09744.9 KFY03084.1 - 0.0042 17.3 0.8 0.0088 16.3 0.8 1.5 1 0 0 1 1 1 1 JNK_SAPK-associated protein-1 AAA PF00004.29 KFY03084.1 - 0.0054 17.2 0.0 9.5 6.7 0.0 3.7 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) VID27 PF08553.10 KFY03084.1 - 0.0065 15.6 2.6 6.4 5.7 0.0 4.1 4 0 0 4 4 4 0 VID27 C-terminal WD40-like domain AAA_33 PF13671.6 KFY03084.1 - 0.012 15.8 0.4 7.7 6.7 0.1 3.0 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 KFY03084.1 - 0.017 15.5 0.3 3.6 8.0 0.0 2.9 2 0 0 2 2 2 0 RNA helicase DUF4423 PF14394.6 KFY03084.1 - 0.031 14.0 0.0 0.41 10.4 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4423) Cytidylate_kin PF02224.18 KFY03084.1 - 0.069 12.9 0.1 7.8 6.2 0.0 2.6 2 0 0 2 2 2 0 Cytidylate kinase PhoH PF02562.16 KFY03084.1 - 0.099 12.1 0.0 6.9 6.1 0.0 2.5 2 0 0 2 2 2 0 PhoH-like protein CbiA PF01656.23 KFY03084.1 - 0.099 12.7 0.5 6.1 6.9 0.1 3.1 3 0 0 3 3 3 0 CobQ/CobB/MinD/ParA nucleotide binding domain Thymidylate_kin PF02223.17 KFY03084.1 - 0.11 12.2 0.5 15 5.2 0.1 2.5 2 0 0 2 2 2 0 Thymidylate kinase Filament PF00038.21 KFY03084.1 - 0.24 10.9 1.0 0.47 10.0 1.0 1.4 1 0 0 1 1 1 0 Intermediate filament protein Peptidase_M16_C PF05193.21 KFY03084.1 - 0.28 11.2 0.6 16 5.4 0.1 3.7 2 1 0 2 2 2 0 Peptidase M16 inactive domain Alfin PF12165.8 KFY03084.1 - 6.2 6.5 6.2 75 3.0 0.1 4.1 3 0 0 3 3 3 0 Alfin HeLo PF14479.6 KFY03085.1 - 1.4e-41 142.6 0.3 1.7e-41 142.3 0.3 1.1 1 0 0 1 1 1 1 Prion-inhibition and propagation DUF1192 PF06698.11 KFY03085.1 - 0.14 12.2 1.4 9.3 6.4 0.5 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF1192) zf-C2H2 PF00096.26 KFY03086.1 - 1.6e-09 37.7 16.6 0.00069 19.9 2.8 3.3 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFY03086.1 - 5.2e-07 30.0 15.0 0.017 15.9 0.1 3.4 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_aberr PF17017.5 KFY03086.1 - 0.0018 18.4 3.0 0.0018 18.4 3.0 1.5 2 0 0 2 2 2 1 Aberrant zinc-finger zf-C2H2_6 PF13912.6 KFY03086.1 - 0.005 16.8 0.1 0.005 16.8 0.1 2.6 3 0 0 3 3 3 1 C2H2-type zinc finger Oxidored-like PF09791.9 KFY03086.1 - 0.0061 16.2 0.1 0.015 15.0 0.1 1.7 1 0 0 1 1 1 1 Oxidoreductase-like protein, N-terminal zf_UBZ PF18439.1 KFY03086.1 - 0.022 14.4 0.1 0.045 13.4 0.1 1.5 1 0 0 1 1 1 0 Ubiquitin-Binding Zinc Finger zf-C2H2_3rep PF18868.1 KFY03086.1 - 0.022 15.4 2.4 4.2 8.1 0.7 2.2 1 1 1 2 2 2 0 Zinc finger C2H2-type, 3 repeats zf-H2C2_2 PF13465.6 KFY03086.1 - 0.03 14.8 14.7 1.1 9.8 0.4 4.1 5 0 0 5 5 5 0 Zinc-finger double domain zf-H2C2_5 PF13909.6 KFY03086.1 - 0.041 13.6 1.2 0.041 13.6 1.2 3.9 4 0 0 4 4 4 0 C2H2-type zinc-finger domain zf-C2H2_12 PF18658.1 KFY03086.1 - 0.05 13.2 7.9 0.57 9.8 0.6 2.7 1 1 2 3 3 3 0 Zinc-finger C2H2-type WD40 PF00400.32 KFY03087.1 - 1.6e-132 427.5 43.4 1.1e-10 41.9 0.1 13.7 13 0 0 13 13 13 13 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFY03087.1 - 1.1e-36 125.0 11.4 0.013 15.8 0.0 12.4 1 1 11 12 12 12 11 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KFY03087.1 - 2.9e-16 59.9 0.1 0.001 19.0 0.0 5.8 1 1 5 6 6 6 4 Eukaryotic translation initiation factor eIF2A WD40_like PF17005.5 KFY03087.1 - 5.5e-11 42.3 0.0 1.1 8.5 0.0 6.9 7 1 0 7 7 7 3 WD40-like domain Frtz PF11768.8 KFY03087.1 - 1.1e-10 40.5 0.0 4.4 5.5 0.0 8.3 1 1 5 8 8 8 3 WD repeat-containing and planar cell polarity effector protein Fritz Ge1_WD40 PF16529.5 KFY03087.1 - 4.4e-10 39.1 9.2 0.73 8.7 0.1 9.1 1 1 8 10 10 10 2 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 KFY03087.1 - 2.9e-09 36.6 1.5 26 4.9 0.0 9.5 10 0 0 10 10 10 0 WD40-like Beta Propeller Repeat NACHT PF05729.12 KFY03087.1 - 4.8e-09 36.4 0.0 1e-08 35.3 0.0 1.5 1 0 0 1 1 1 1 NACHT domain Cytochrom_D1 PF02239.16 KFY03087.1 - 2.1e-08 33.1 13.5 0.0035 15.9 0.2 5.5 1 1 3 6 6 6 4 Cytochrome D1 heme domain Proteasome_A_N PF10584.9 KFY03087.1 - 0.00019 21.0 1.8 67 3.3 0.0 6.8 6 0 0 6 6 6 0 Proteasome subunit A N-terminal signature AAA_16 PF13191.6 KFY03087.1 - 0.00033 21.1 0.1 0.0011 19.4 0.1 1.9 1 0 0 1 1 1 1 AAA ATPase domain AAA_18 PF13238.6 KFY03087.1 - 0.0037 17.8 0.0 0.016 15.7 0.0 2.1 2 0 0 2 2 1 1 AAA domain AAA_22 PF13401.6 KFY03087.1 - 0.049 13.9 0.0 0.26 11.5 0.0 2.0 2 0 0 2 2 2 0 AAA domain HARP PF07443.13 KFY03087.1 - 0.052 13.2 0.0 55 3.5 0.0 4.1 4 0 0 4 4 4 0 HepA-related protein (HARP) AAA_30 PF13604.6 KFY03087.1 - 0.069 12.9 0.0 0.22 11.2 0.0 1.9 1 0 0 1 1 1 0 AAA domain APS_kinase PF01583.20 KFY03087.1 - 0.1 12.5 0.0 0.2 11.5 0.0 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase MarR_2 PF12802.7 KFY03087.1 - 0.18 11.7 2.6 0.12 12.3 0.4 1.9 2 0 0 2 2 1 0 MarR family Emaravirus_P4 PF16505.5 KFY03087.1 - 0.19 10.8 0.0 10 5.1 0.0 3.8 6 0 0 6 6 6 0 P4 movement protein of Emaravirus, and the 30K superfamily NAGPA PF09992.9 KFY03087.1 - 0.35 11.1 1.5 11 6.1 0.0 3.8 2 1 3 5 5 5 0 Phosphodiester glycosidase HMA PF00403.26 KFY03087.1 - 2.7 8.5 11.3 8.6 6.9 0.0 6.4 10 0 0 10 10 5 0 Heavy-metal-associated domain SIR2 PF02146.17 KFY03088.1 - 6.4e-16 58.8 0.0 1.5e-15 57.6 0.0 1.7 1 0 0 1 1 1 1 Sir2 family Peptidase_C48 PF02902.19 KFY03088.1 - 1.2e-10 41.6 0.1 6.2e-10 39.3 0.1 2.2 1 1 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain FAD_binding_8 PF08022.12 KFY03088.1 - 2e-08 34.3 0.0 5.7e-08 32.8 0.0 1.8 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.12 KFY03088.1 - 0.0028 17.8 0.0 0.012 15.7 0.0 2.0 2 0 0 2 2 2 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.19 KFY03088.1 - 0.012 15.7 2.5 0.026 14.7 1.8 2.0 2 0 0 2 2 2 0 Ferric reductase like transmembrane component Pre-PUA PF17832.1 KFY03089.1 - 1.2 9.8 5.2 12 6.7 0.6 3.4 3 0 0 3 3 3 0 Pre-PUA-like domain Dapper PF15268.6 KFY03089.1 - 4.8 5.9 34.1 2.4 6.9 12.7 2.1 2 0 0 2 2 2 0 Dapper DUF3723 PF12520.8 KFY03092.1 - 2e-115 386.4 0.0 6.1e-106 355.1 0.0 2.2 1 1 1 2 2 2 2 Protein of unknown function (DUF3723) Pkinase PF00069.25 KFY03093.1 - 8.9e-09 35.1 0.0 7.8e-08 32.0 0.0 2.1 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFY03093.1 - 2.9e-08 33.3 0.0 9.7e-08 31.6 0.0 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase IMS_HHH PF11798.8 KFY03093.1 - 0.16 12.4 0.0 0.56 10.7 0.0 1.9 1 0 0 1 1 1 0 IMS family HHH motif FUSC_2 PF13515.6 KFY03095.1 - 0.14 12.2 20.3 0.36 10.9 1.6 3.1 1 1 2 3 3 3 0 Fusaric acid resistance protein-like TraP PF07296.11 KFY03095.1 - 0.23 10.6 0.6 0.49 9.5 0.1 1.7 2 0 0 2 2 2 0 TraP protein Meckelin PF09773.9 KFY03095.1 - 0.69 7.9 2.9 0.95 7.5 2.9 1.1 1 0 0 1 1 1 0 Meckelin (Transmembrane protein 67) F-box-like_2 PF13013.6 KFY03096.1 - 0.11 12.5 0.0 0.18 11.8 0.0 1.6 1 1 0 1 1 1 0 F-box-like domain SesA PF17107.5 KFY03097.1 - 4.4e-06 26.9 0.0 1.8e-05 24.9 0.0 2.0 2 0 0 2 2 2 1 N-terminal domain on NACHT_NTPase and P-loop NTPases NACHT PF05729.12 KFY03097.1 - 6.2e-06 26.2 0.0 1.3e-05 25.2 0.0 1.6 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.6 KFY03097.1 - 0.00033 21.0 0.0 0.0011 19.2 0.0 1.9 2 0 0 2 2 2 1 AAA domain TBCC_N PF16752.5 KFY03097.1 - 0.014 15.9 0.1 0.68 10.4 0.0 2.7 3 0 0 3 3 3 0 Tubulin-specific chaperone C N-terminal domain AAA PF00004.29 KFY03097.1 - 0.17 12.3 0.4 2.5 8.5 0.0 2.8 2 1 1 3 3 3 0 ATPase family associated with various cellular activities (AAA) F-box_4 PF15966.5 KFY03100.1 - 0.0003 20.7 0.0 0.00047 20.0 0.0 1.3 1 0 0 1 1 1 1 F-box F-box PF00646.33 KFY03100.1 - 0.00057 19.7 0.6 0.0013 18.6 0.6 1.6 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 KFY03100.1 - 0.00087 19.1 0.5 0.0019 18.0 0.5 1.6 1 0 0 1 1 1 1 F-box-like Phage_C PF12025.8 KFY03100.1 - 0.13 12.2 0.0 0.26 11.2 0.0 1.6 1 0 0 1 1 1 0 Phage protein C MFS_1 PF07690.16 KFY03103.1 - 4.4e-31 108.1 30.8 6.6e-31 107.5 30.8 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KFY03103.1 - 3.1e-05 23.0 10.8 3.1e-05 23.0 10.8 1.7 2 0 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.13 KFY03103.1 - 3.5e-05 22.4 4.6 5.1e-05 21.9 4.6 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Adaptin_binding PF10199.9 KFY03109.1 - 0.00068 20.2 0.2 0.0015 19.2 0.2 1.6 1 0 0 1 1 1 1 Alpha and gamma adaptin binding protein p34 FAD_binding_7 PF03441.14 KFY03110.1 - 1.4e-77 259.8 0.4 2.2e-77 259.1 0.4 1.3 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.18 KFY03110.1 - 1.1e-40 139.4 0.0 1.8e-40 138.6 0.0 1.3 1 0 0 1 1 1 1 DNA photolyase Homeodomain PF00046.29 KFY03111.1 - 5.2e-20 71.0 3.4 1e-19 70.1 3.4 1.5 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 KFY03111.1 - 0.00042 20.2 0.2 0.0013 18.6 0.2 1.9 1 0 0 1 1 1 1 Homeobox KN domain MIP-T3_C PF17749.1 KFY03111.1 - 0.059 13.3 1.5 0.097 12.6 1.5 1.2 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 C-terminal region AsmA_1 PF13109.6 KFY03111.1 - 0.11 11.9 0.0 0.18 11.3 0.0 1.3 1 0 0 1 1 1 0 AsmA-like C-terminal region VCBS PF13517.6 KFY03115.1 - 1.9e-20 73.2 16.3 2.9e-09 37.4 1.2 5.4 3 1 2 5 5 5 4 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella TcdB_toxin_midN PF12256.8 KFY03115.1 - 2.1e-05 24.0 0.0 1.9 7.8 0.0 4.0 4 0 0 4 4 4 2 Insecticide toxin TcdB middle/N-terminal region FG-GAP PF01839.23 KFY03115.1 - 0.057 13.6 0.1 0.057 13.6 0.1 3.2 3 0 0 3 3 3 0 FG-GAP repeat WD40 PF00400.32 KFY03116.1 - 8.1e-11 42.3 4.3 0.00064 20.5 0.1 4.6 4 1 1 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFY03116.1 - 0.0019 18.5 0.0 2.1 8.7 0.0 3.7 2 1 1 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain PQQ_3 PF13570.6 KFY03116.1 - 0.0045 17.4 2.4 1.6 9.4 0.1 4.0 3 1 1 4 4 4 1 PQQ-like domain PQQ_2 PF13360.6 KFY03116.1 - 0.012 15.2 0.1 1.5 8.4 0.0 2.5 1 1 1 2 2 2 0 PQQ-like domain WI12 PF07107.11 KFY03116.1 - 0.021 14.9 0.1 0.99 9.6 0.1 2.4 1 1 1 2 2 2 0 Wound-induced protein WI12 Nup160 PF11715.8 KFY03116.1 - 0.26 9.9 0.5 1.8 7.1 0.1 2.3 1 1 1 2 2 2 0 Nucleoporin Nup120/160 SprA-related PF12118.8 KFY03122.1 - 3 6.9 7.0 3.7 6.6 7.0 1.1 1 0 0 1 1 1 0 SprA-related family Peptidase_C65 PF10275.9 KFY03137.1 - 1.9e-49 168.4 0.1 4e-42 144.4 0.0 2.1 1 1 1 2 2 2 2 Peptidase C65 Otubain Fungal_trans PF04082.18 KFY03142.1 - 8.6e-25 87.3 1.5 1.4e-24 86.6 1.5 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain HMG_box PF00505.19 KFY03142.1 - 2e-15 57.0 0.5 5e-15 55.7 0.5 1.8 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KFY03142.1 - 2.1e-12 47.4 0.8 4.6e-12 46.4 0.8 1.6 1 0 0 1 1 1 1 HMG-box domain SAM_1 PF00536.30 KFY03142.1 - 2.7e-09 37.3 0.0 5.9e-09 36.2 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 KFY03142.1 - 0.00011 22.2 0.0 0.00023 21.2 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Fungal_trans PF04082.18 KFY03143.1 - 2.3e-08 33.4 0.2 3.7e-08 32.7 0.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KFY03144.1 - 0.0057 16.8 6.8 0.0095 16.0 6.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ecl1 PF12855.7 KFY03145.1 - 2.9e-11 44.8 1.9 2.9e-11 44.8 1.9 1.8 2 0 0 2 2 2 1 ECL1/2/3 zinc binding proteins PLATZ PF04640.14 KFY03145.1 - 0.0094 16.6 0.3 0.014 16.0 0.3 1.4 1 0 0 1 1 1 1 PLATZ transcription factor YacG PF03884.14 KFY03145.1 - 0.028 14.1 4.6 0.13 12.1 4.1 2.0 1 1 1 2 2 2 0 DNA gyrase inhibitor YacG zf-FLZ PF04570.14 KFY03145.1 - 0.96 9.0 6.1 13 5.3 6.1 2.3 1 1 0 1 1 1 0 zinc-finger of the FCS-type, C2-C2 DUF4770 PF15994.5 KFY03147.1 - 2.4 8.4 12.6 3.3 7.9 12.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4770) MFS_1 PF07690.16 KFY03149.1 - 1.6e-09 37.1 52.8 2.5e-08 33.2 51.8 2.8 2 1 0 2 2 2 1 Major Facilitator Superfamily Peptidase_M3 PF01432.20 KFY03152.1 - 1.4e-153 512.5 0.0 1.7e-153 512.2 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M3 Myb_DNA-binding PF00249.31 KFY03153.1 - 6.6e-10 39.0 0.1 1.6e-08 34.6 0.0 2.7 2 0 0 2 2 2 1 Myb-like DNA-binding domain ZZ PF00569.17 KFY03153.1 - 2e-08 33.9 7.2 3.6e-08 33.1 7.2 1.4 1 0 0 1 1 1 1 Zinc finger, ZZ type SWIRM PF04433.17 KFY03153.1 - 3.8e-07 30.4 0.0 1.4e-06 28.5 0.0 1.9 2 0 0 2 2 2 1 SWIRM domain GerPC PF10737.9 KFY03154.1 - 3.9e-05 23.8 4.5 3.9e-05 23.8 4.5 1.9 1 1 1 2 2 2 1 Spore germination protein GerPC DUF2939 PF11159.8 KFY03154.1 - 0.018 15.4 2.1 1.7 9.1 0.2 2.9 1 1 3 4 4 4 0 Protein of unknown function (DUF2939) DUF45 PF01863.17 KFY03154.1 - 0.036 14.1 8.2 0.043 13.9 0.4 2.4 1 1 1 2 2 2 0 Protein of unknown function DUF45 RHD3 PF05879.12 KFY03154.1 - 0.07 11.3 9.9 0.091 10.9 9.9 1.1 1 0 0 1 1 1 0 Root hair defective 3 GTP-binding protein (RHD3) Vps39_2 PF10367.9 KFY03154.1 - 0.089 13.2 9.5 0.46 10.9 0.3 3.3 1 1 2 3 3 3 0 Vacuolar sorting protein 39 domain 2 DUF445 PF04286.12 KFY03154.1 - 0.11 12.2 13.0 0.097 12.5 11.4 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF445) DUF4403 PF14356.6 KFY03154.1 - 0.15 10.7 2.8 0.19 10.3 0.9 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4403) Minor_tail_Z PF06763.11 KFY03154.1 - 0.24 11.2 7.7 4.5 7.0 0.2 3.4 1 1 3 4 4 4 0 Prophage minor tail protein Z (GPZ) Glycoprot_B_PH2 PF17417.2 KFY03154.1 - 0.3 11.5 2.3 2.4 8.5 1.0 2.5 1 1 2 3 3 3 0 Herpesvirus Glycoprotein B PH-like domain DUF4410 PF14366.6 KFY03154.1 - 0.82 9.6 11.7 1.1 9.2 1.7 3.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4410) FHIPEP PF00771.20 KFY03154.1 - 0.82 8.1 7.0 0.52 8.7 5.1 1.5 1 1 0 1 1 1 0 FHIPEP family FAA_hydrolase_N PF09298.11 KFY03154.1 - 1.1 9.5 4.6 24 5.2 4.6 2.6 1 1 0 1 1 1 0 Fumarylacetoacetase N-terminal DUF5499 PF17603.2 KFY03154.1 - 1.3 9.7 4.3 15 6.3 0.7 2.6 1 1 1 2 2 2 0 Family of unknown function (DUF5499) MgtE_N PF03448.17 KFY03154.1 - 1.8 9.2 17.6 0.19 12.4 6.7 3.0 1 1 2 3 3 3 0 MgtE intracellular N domain Spore_II_R PF09551.10 KFY03154.1 - 3 8.3 10.0 13 6.3 4.3 2.6 1 1 2 3 3 3 0 Stage II sporulation protein R (spore_II_R) Annexin PF00191.20 KFY03154.1 - 3.3 7.9 6.0 13 5.9 0.3 3.4 1 1 1 3 3 3 0 Annexin DUF1722 PF08349.11 KFY03154.1 - 4.3 7.7 9.9 6.6 7.1 2.3 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1722) DUF2924 PF11149.8 KFY03154.1 - 4.4 7.7 11.0 2.6 8.4 2.8 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2924) DUF1104 PF06518.11 KFY03154.1 - 5.1 7.5 21.1 1.5 9.2 8.8 3.1 1 1 2 3 3 3 0 Protein of unknown function (DUF1104) DUF945 PF06097.11 KFY03154.1 - 7.2 5.6 11.1 10 5.1 11.1 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF945) LapA_dom PF06305.11 KFY03155.1 - 0.61 9.9 7.7 0.29 11.0 0.3 2.4 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain DUF2781 PF10914.8 KFY03156.1 - 3.2e-34 118.5 10.1 3.6e-34 118.3 10.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2781) DUF2273 PF10031.9 KFY03157.1 - 0.088 12.8 0.1 0.088 12.8 0.1 2.9 4 0 0 4 4 4 0 Small integral membrane protein (DUF2273) DUF3425 PF11905.8 KFY03158.1 - 3.3e-18 65.9 0.1 6.3e-18 64.9 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) bZIP_1 PF00170.21 KFY03158.1 - 3.4 7.8 7.9 5.3 7.2 7.9 1.3 1 0 0 1 1 1 0 bZIP transcription factor Pyr_redox_2 PF07992.14 KFY03159.1 - 1.2e-33 116.7 0.0 1.5e-33 116.3 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KFY03159.1 - 5.1e-13 49.4 0.9 8e-10 39.1 0.1 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KFY03159.1 - 1.9e-06 27.4 0.0 6.3e-05 22.4 0.0 2.3 1 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KFY03159.1 - 0.0003 20.1 0.2 0.016 14.3 0.1 2.1 2 0 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) Lycopene_cycl PF05834.12 KFY03159.1 - 0.043 12.9 0.6 2.5 7.0 0.0 2.8 4 0 0 4 4 4 0 Lycopene cyclase protein adh_short PF00106.25 KFY03160.1 - 1.8e-28 99.3 0.1 2.6e-20 72.7 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KFY03160.1 - 4.3e-19 69.0 0.1 5.5e-12 45.7 0.0 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KFY03160.1 - 3.3e-06 27.1 0.1 7.2e-06 26.0 0.0 1.6 2 0 0 2 2 2 1 KR domain Polysacc_synt_2 PF02719.15 KFY03160.1 - 0.098 11.8 0.0 0.14 11.3 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein PRANC PF09372.10 KFY03160.1 - 0.11 12.9 0.0 0.23 11.8 0.0 1.5 1 0 0 1 1 1 0 PRANC domain DUF2399 PF09664.10 KFY03160.1 - 0.11 12.4 0.1 12 5.7 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function C-terminus (DUF2399) Nucleoporin_N PF08801.11 KFY03161.1 - 4.6e-98 328.8 0.2 6.8e-98 328.2 0.2 1.3 1 0 0 1 1 1 1 Nup133 N terminal like Pkinase PF00069.25 KFY03161.1 - 1.4e-68 231.1 0.0 3.2e-68 230.0 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Nucleoporin_C PF03177.14 KFY03161.1 - 1e-51 176.5 0.2 7.2e-51 173.6 0.2 1.8 1 1 0 1 1 1 1 Non-repetitive/WGA-negative nucleoporin C-terminal Pkinase_Tyr PF07714.17 KFY03161.1 - 4.4e-33 114.6 0.0 8e-33 113.8 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.24 KFY03161.1 - 2.2e-09 37.9 0.3 6e-09 36.5 0.3 1.8 1 0 0 1 1 1 1 Protein kinase C terminal domain Haspin_kinase PF12330.8 KFY03161.1 - 9.9e-06 24.7 0.0 1.8e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 KFY03161.1 - 0.018 14.4 0.0 0.03 13.6 0.0 1.3 1 0 0 1 1 1 0 Kinase-like DUF3802 PF12290.8 KFY03161.1 - 0.041 14.4 0.4 0.16 12.5 0.1 2.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3802) C2 PF00168.30 KFY03161.1 - 0.15 12.4 0.0 0.34 11.2 0.0 1.5 1 0 0 1 1 1 0 C2 domain Ferric_reduct PF01794.19 KFY03171.1 - 2.6e-20 72.8 19.3 2.6e-20 72.8 19.3 2.5 3 1 1 4 4 4 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.12 KFY03171.1 - 2.3e-13 50.2 0.1 5.4e-13 49.0 0.1 1.6 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.12 KFY03171.1 - 2.4e-11 44.0 0.0 4.1e-11 43.3 0.0 1.4 1 0 0 1 1 1 1 Ferric reductase NAD binding domain TMEM214 PF10151.9 KFY03171.1 - 0.29 9.5 0.4 0.41 9.0 0.4 1.1 1 0 0 1 1 1 0 TMEM214, C-terminal, caspase 4 activator DUF4405 PF14358.6 KFY03171.1 - 5.9 7.5 25.4 0.054 14.0 2.3 3.8 4 0 0 4 4 4 0 Domain of unknown function (DUF4405) Ctr PF04145.15 KFY03172.1 - 6.8e-20 72.2 12.9 2.7e-19 70.3 12.9 1.8 1 1 0 1 1 1 1 Ctr copper transporter family COesterase PF00135.28 KFY03173.1 - 1.3e-85 288.3 0.0 2.1e-85 287.5 0.0 1.2 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KFY03173.1 - 4.6e-05 23.4 0.8 0.0029 17.5 0.5 3.1 2 1 0 2 2 2 1 alpha/beta hydrolase fold 4HBT PF03061.22 KFY03173.1 - 0.14 12.5 0.0 0.3 11.5 0.0 1.5 1 0 0 1 1 1 0 Thioesterase superfamily COesterase PF00135.28 KFY03174.1 - 9.6e-81 272.2 0.0 8.3e-60 203.1 0.0 3.0 3 0 0 3 3 3 3 Carboxylesterase family Abhydrolase_3 PF07859.13 KFY03174.1 - 5.5e-08 32.9 0.0 1.1e-07 31.9 0.0 1.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold Esterase_phd PF10503.9 KFY03174.1 - 0.0092 15.5 0.3 0.03 13.8 0.1 2.0 2 1 0 2 2 2 1 Esterase PHB depolymerase ABM PF03992.16 KFY03176.1 - 3.5e-05 23.8 0.0 5e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase HHH_4 PF14490.6 KFY03176.1 - 0.12 12.3 0.0 0.18 11.8 0.0 1.2 1 0 0 1 1 1 0 Helix-hairpin-helix containing domain Cupin_5 PF06172.11 KFY03177.1 - 6.3e-49 165.8 0.0 7.5e-49 165.5 0.0 1.1 1 0 0 1 1 1 1 Cupin superfamily (DUF985) COesterase PF00135.28 KFY03178.1 - 4.9e-78 263.3 0.1 1.9e-71 241.5 0.2 2.2 1 1 1 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.13 KFY03178.1 - 3.2e-09 37.0 0.0 5.5e-09 36.2 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Oxidored_FMN PF00724.20 KFY03179.1 - 2.7e-35 122.3 0.0 4e-35 121.7 0.0 1.2 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family HetR_C PF18460.1 KFY03179.1 - 0.016 15.1 0.1 0.048 13.6 0.0 1.8 2 0 0 2 2 2 0 Heterocyst differentiation regulator C-terminal Hood domain Dus PF01207.17 KFY03179.1 - 0.035 13.2 0.0 0.14 11.2 0.0 2.0 1 1 0 1 1 1 0 Dihydrouridine synthase (Dus) AP_endonuc_2 PF01261.24 KFY03179.1 - 0.041 13.3 0.0 5.5 6.4 0.0 2.7 2 1 0 2 2 2 0 Xylose isomerase-like TIM barrel PdxJ PF03740.13 KFY03179.1 - 0.052 12.7 0.1 0.12 11.4 0.0 1.6 2 0 0 2 2 2 0 Pyridoxal phosphate biosynthesis protein PdxJ Vps35 PF03635.17 KFY03180.1 - 0 1035.1 5.0 0 1034.9 5.0 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 35 TFIIA PF03153.13 KFY03180.1 - 0.2 11.6 10.8 0.076 13.0 2.1 2.4 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit RR_TM4-6 PF06459.12 KFY03180.1 - 0.68 9.7 7.6 1.2 8.9 7.6 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Bromodomain PF00439.25 KFY03181.1 - 2.1e-23 82.2 0.5 4e-23 81.3 0.5 1.4 1 0 0 1 1 1 1 Bromodomain Acetyltransf_1 PF00583.25 KFY03181.1 - 1.8e-08 34.7 0.0 3.4e-08 33.7 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KFY03181.1 - 2.4e-06 27.5 0.1 5.1e-06 26.4 0.1 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KFY03181.1 - 0.00024 21.4 0.1 0.00061 20.2 0.1 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Proteasom_Rpn13 PF04683.13 KFY03183.1 - 3.2e-28 98.1 0.0 5.2e-28 97.4 0.0 1.3 1 0 0 1 1 1 1 Proteasome complex subunit Rpn13 ubiquitin receptor RPN13_C PF16550.5 KFY03183.1 - 3.6e-13 49.7 0.9 1.4e-11 44.6 0.9 2.3 1 1 0 1 1 1 1 UCH-binding domain SNF5 PF04855.12 KFY03184.1 - 3.3e-94 315.1 0.0 6.7e-94 314.1 0.0 1.5 1 0 0 1 1 1 1 SNF5 / SMARCB1 / INI1 Ribosomal_L6e PF01159.19 KFY03184.1 - 9.8e-39 132.3 0.3 9.8e-39 132.3 0.3 2.1 2 0 0 2 2 2 1 Ribosomal protein L6e GATA PF00320.27 KFY03184.1 - 3.3e-05 23.4 3.2 7.8e-05 22.2 3.2 1.7 1 0 0 1 1 1 1 GATA zinc finger Rubredoxin_2 PF18073.1 KFY03184.1 - 0.013 15.3 4.5 0.14 11.9 0.8 2.4 2 0 0 2 2 2 0 Rubredoxin metal binding domain cIII PF08134.11 KFY03184.1 - 0.061 13.1 0.1 0.22 11.3 0.1 2.0 1 0 0 1 1 1 0 cIII protein family Ribosomal_L7Ae PF01248.26 KFY03185.1 - 7.2e-22 76.9 0.0 8.1e-22 76.8 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Aminotran_3 PF00202.21 KFY03188.1 - 1.7e-74 250.9 0.0 2e-74 250.7 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III DUF2838 PF10998.8 KFY03189.1 - 6e-46 155.3 7.5 6e-46 155.3 7.5 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF2838) DUF1319 PF07028.11 KFY03189.1 - 0.048 13.9 0.3 0.09 13.0 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1319) DUF1640 PF07798.11 KFY03189.1 - 0.074 13.1 1.7 0.11 12.5 0.4 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1640) DUF4618 PF15397.6 KFY03189.1 - 0.17 11.3 0.7 16 4.8 0.7 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4618) SMC_N PF02463.19 KFY03190.1 - 6.9e-59 198.9 6.5 3.4e-57 193.4 6.5 2.6 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 KFY03190.1 - 1.5e-25 89.8 0.0 1e-24 87.1 0.0 2.6 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.6 KFY03190.1 - 8e-11 42.3 14.1 3.1e-05 23.9 0.1 4.3 4 0 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 KFY03190.1 - 5.1e-08 32.5 0.1 1.2e-07 31.4 0.1 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_15 PF13175.6 KFY03190.1 - 1.5e-07 31.5 11.9 1.5e-07 31.5 11.9 4.3 2 2 2 4 4 3 1 AAA ATPase domain HMMR_N PF15905.5 KFY03190.1 - 8.7e-05 22.1 26.4 8.7e-05 22.1 26.4 4.8 4 1 1 5 5 5 2 Hyaluronan mediated motility receptor N-terminal FPP PF05911.11 KFY03190.1 - 0.00014 20.2 15.6 0.00014 20.2 15.6 3.5 4 0 0 4 4 4 2 Filament-like plant protein, long coiled-coil AAA_13 PF13166.6 KFY03190.1 - 0.00071 18.4 12.3 0.00071 18.4 12.3 6.7 2 2 4 7 7 7 3 AAA domain SbcCD_C PF13558.6 KFY03190.1 - 0.0062 16.8 0.0 0.041 14.1 0.0 2.5 2 0 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_22 PF13401.6 KFY03190.1 - 0.59 10.4 6.4 24 5.2 0.0 4.8 4 1 0 4 4 4 0 AAA domain ABC_tran PF00005.27 KFY03190.1 - 1 9.9 0.0 1 9.9 0.0 6.8 4 2 0 4 4 2 0 ABC transporter Sugarporin_N PF11471.8 KFY03190.1 - 6.8 6.7 11.9 3.7 7.6 1.3 3.7 3 0 0 3 3 3 0 Maltoporin periplasmic N-terminal extension WD40 PF00400.32 KFY03191.1 - 1.6e-19 69.9 12.2 0.00089 20.0 0.0 6.7 6 0 0 6 6 6 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFY03191.1 - 6.7e-13 48.8 5.1 0.0002 21.6 0.3 4.3 3 1 1 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KFY03191.1 - 8.9e-07 29.0 0.1 0.004 17.1 0.1 3.3 2 1 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A Arf PF00025.21 KFY03192.1 - 5.8e-64 214.7 0.0 9.8e-64 214.0 0.0 1.4 1 0 0 1 1 1 1 ADP-ribosylation factor family DUF3336 PF11815.8 KFY03192.1 - 7.8e-48 161.7 2.7 1.4e-47 160.9 2.7 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3336) Patatin PF01734.22 KFY03192.1 - 5.7e-17 62.6 0.2 2.2e-16 60.6 0.2 2.0 1 1 0 1 1 1 1 Patatin-like phospholipase G-alpha PF00503.20 KFY03192.1 - 2.4e-10 40.1 0.0 1.3e-07 31.1 0.0 2.3 1 1 1 2 2 2 2 G-protein alpha subunit SRPRB PF09439.10 KFY03192.1 - 9.3e-08 31.7 0.0 1.9e-07 30.7 0.0 1.5 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Roc PF08477.13 KFY03192.1 - 1.4e-06 28.5 0.0 3.5e-06 27.2 0.0 1.7 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 KFY03192.1 - 1.9e-06 28.0 0.0 4.4e-06 26.8 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase Ras PF00071.22 KFY03192.1 - 8.8e-06 25.4 0.0 1.6e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.12 KFY03192.1 - 0.00012 21.5 0.0 0.00019 20.9 0.0 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region DUF2347 PF09804.9 KFY03193.1 - 1.3e-98 330.0 0.0 1.7e-98 329.7 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2347) DUF4484 PF14831.6 KFY03193.1 - 9.1e-53 179.4 1.6 2.3e-50 171.6 1.6 2.3 1 1 0 1 1 1 1 Domain of unknown function (DUF4484) Avl9 PF09794.9 KFY03193.1 - 0.0011 17.7 0.0 0.011 14.5 0.0 2.1 2 0 0 2 2 2 1 Transport protein Avl9 SPA PF08616.10 KFY03193.1 - 0.0097 15.9 0.0 0.029 14.3 0.0 1.7 1 1 0 1 1 1 1 Stabilization of polarity axis RRM_1 PF00076.22 KFY03195.1 - 8.7e-19 67.1 0.0 1.2e-18 66.7 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 KFY03195.1 - 0.00019 21.0 0.0 0.00028 20.5 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF1793 PF08760.11 KFY03196.1 - 1.4e-71 240.3 0.1 2.5e-71 239.5 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1793) DUF4965 PF16335.5 KFY03196.1 - 1.3e-63 213.7 0.4 7.2e-48 162.5 0.0 2.4 2 0 0 2 2 2 2 Domain of unknown function (DUF4965) DUF5127 PF17168.4 KFY03196.1 - 1.8e-42 145.7 0.2 4.5e-42 144.4 0.2 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF5127) DUF4964 PF16334.5 KFY03196.1 - 0.0093 15.5 0.0 0.022 14.3 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4964) DUF2457 PF10446.9 KFY03197.1 - 8e-174 579.2 39.2 8e-174 579.2 39.2 2.9 2 1 1 3 3 3 1 Protein of unknown function (DUF2457) Nop14 PF04147.12 KFY03197.1 - 1.6 6.8 35.5 0.58 8.3 28.8 2.2 2 0 0 2 2 2 0 Nop14-like family CDC45 PF02724.14 KFY03197.1 - 8.6 4.5 28.8 2.6 6.2 17.7 2.2 2 0 0 2 2 2 0 CDC45-like protein POT1 PF02765.17 KFY03201.1 - 1.4e-08 34.7 0.0 3.3e-08 33.5 0.0 1.6 1 0 0 1 1 1 1 Telomeric single stranded DNA binding POT1/CDC13 IF4E PF01652.18 KFY03203.1 - 7.5e-56 188.3 0.1 1e-55 187.9 0.1 1.2 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E Peptidase_C48 PF02902.19 KFY03204.1 - 2.4e-32 112.5 0.0 5.3e-32 111.4 0.0 1.6 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain F-box-like PF12937.7 KFY03205.1 - 9.4e-07 28.6 2.4 1.2e-06 28.3 0.5 2.2 2 1 0 2 2 2 1 F-box-like LRR_4 PF12799.7 KFY03205.1 - 0.0065 16.9 2.5 3.9 8.0 0.1 3.7 2 1 1 3 3 3 1 Leucine Rich repeats (2 copies) GGACT PF06094.12 KFY03208.1 - 4.4e-15 56.3 0.1 1.7e-14 54.5 0.1 1.9 1 1 0 1 1 1 1 Gamma-glutamyl cyclotransferase, AIG2-like Glyco_hydro_61 PF03443.14 KFY03211.1 - 0.033 14.1 0.0 0.085 12.8 0.0 1.6 1 0 0 1 1 1 0 Glycosyl hydrolase family 61 DUF3433 PF11915.8 KFY03212.1 - 3.2e-38 130.1 19.4 5.3e-23 81.3 3.4 3.9 4 0 0 4 4 4 2 Protein of unknown function (DUF3433) DUF4064 PF13273.6 KFY03212.1 - 1.1 9.6 11.8 2.1 8.7 0.2 3.7 4 0 0 4 4 4 0 Protein of unknown function (DUF4064) UPF0029 PF01205.19 KFY03213.1 - 3.5e-34 117.3 0.0 5.3e-34 116.7 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized protein family UPF0029 RWD PF05773.22 KFY03213.1 - 9.6e-06 25.9 0.0 8.7e-05 22.8 0.0 2.2 1 1 0 1 1 1 1 RWD domain DUF4113 PF13438.6 KFY03213.1 - 0.16 12.1 0.1 0.62 10.2 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4113) MPM1 PF17234.2 KFY03214.1 - 0.0013 19.0 3.5 0.0024 18.2 3.5 1.4 1 0 0 1 1 1 1 Mitochondrial peculiar membrane protein 1 AMP-binding PF00501.28 KFY03216.1 - 1.5e-17 63.3 0.0 4.8e-09 35.3 0.0 2.1 2 0 0 2 2 2 2 AMP-binding enzyme DUF3435 PF11917.8 KFY03223.1 - 4e-07 29.3 4.8 1.1e-06 27.9 0.3 1.9 1 1 1 2 2 2 2 Protein of unknown function (DUF3435) MFS_1 PF07690.16 KFY03225.1 - 8.1e-27 94.1 48.4 2.9e-25 89.0 43.7 3.1 2 1 0 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 KFY03225.1 - 9.3e-20 70.6 15.8 2.8e-19 69.0 15.8 1.7 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF4519 PF15012.6 KFY03225.1 - 0.55 10.4 4.8 1.5 9.1 0.2 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4519) FAD_binding_3 PF01494.19 KFY03226.1 - 9.8e-20 71.1 0.1 3.1e-19 69.4 0.1 1.8 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 KFY03226.1 - 2.7e-06 27.5 1.1 6.4e-06 26.3 1.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 KFY03226.1 - 2.1e-05 23.8 1.0 3.2e-05 23.2 1.0 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 KFY03226.1 - 0.00016 21.0 1.9 0.0003 20.1 1.9 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KFY03226.1 - 0.002 17.8 7.6 0.0039 16.8 4.6 2.1 1 1 0 2 2 2 1 FAD dependent oxidoreductase FAD_oxidored PF12831.7 KFY03226.1 - 0.0029 17.0 1.4 0.0047 16.3 1.4 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 KFY03226.1 - 0.0052 17.3 1.4 0.012 16.2 1.4 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 KFY03226.1 - 0.0086 15.4 1.2 0.011 15.1 0.1 1.6 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain GIDA PF01134.22 KFY03226.1 - 0.056 12.5 2.6 0.08 12.0 2.6 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A HI0933_like PF03486.14 KFY03226.1 - 0.1 11.3 1.5 0.17 10.6 1.5 1.3 1 0 0 1 1 1 0 HI0933-like protein Rossmann-like PF10727.9 KFY03226.1 - 0.11 12.4 1.9 0.16 11.9 0.3 2.0 2 0 0 2 2 2 0 Rossmann-like domain Pyr_redox_3 PF13738.6 KFY03226.1 - 0.15 11.3 2.5 0.27 10.5 2.5 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase MCRA PF06100.11 KFY03226.1 - 0.3 9.8 0.3 0.41 9.4 0.3 1.1 1 0 0 1 1 1 0 MCRA family Fungal_trans PF04082.18 KFY03227.1 - 2.3e-18 66.2 0.0 4.9e-18 65.1 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KFY03227.1 - 4.9e-08 33.0 10.5 1e-07 31.9 10.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain APG6_N PF17675.1 KFY03227.1 - 3 8.4 13.9 0.18 12.3 5.6 2.9 3 0 0 3 3 3 0 Apg6 coiled-coil region Glyco_hydro_61 PF03443.14 KFY03228.1 - 2.9e-48 164.5 0.0 3.3e-48 164.3 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 COesterase PF00135.28 KFY03231.1 - 4.5e-73 246.9 0.0 1.1e-72 245.6 0.0 1.5 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KFY03231.1 - 5.8e-12 45.9 0.2 1.8e-11 44.3 0.2 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold TauD PF02668.16 KFY03233.1 - 1.2e-13 51.5 1.2 4e-09 36.7 0.1 2.2 2 0 0 2 2 2 2 Taurine catabolism dioxygenase TauD, TfdA family CsiD PF08943.10 KFY03233.1 - 0.0041 16.3 0.0 0.0071 15.5 0.0 1.3 1 0 0 1 1 1 1 CsiD Enolase_like_N PF18374.1 KFY03235.1 - 0.75 9.2 3.0 7.9 6.0 0.3 2.4 1 1 1 2 2 2 0 Enolase N-terminal domain-like F-box PF00646.33 KFY03238.1 - 0.0038 17.1 0.0 0.0091 15.9 0.0 1.6 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 KFY03238.1 - 0.0073 16.2 0.1 0.039 13.9 0.0 2.2 2 0 0 2 2 2 1 F-box-like NIF PF03031.18 KFY03241.1 - 2.7e-41 140.9 0.0 3.7e-41 140.5 0.0 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase Kinesin PF00225.23 KFY03243.1 - 2.7e-116 388.2 0.7 4.6e-116 387.4 0.3 1.6 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 KFY03243.1 - 2e-28 99.2 0.0 4.9e-28 97.9 0.0 1.7 1 0 0 1 1 1 1 Microtubule binding AAA_33 PF13671.6 KFY03243.1 - 0.01 16.0 0.3 0.056 13.6 0.0 2.4 2 0 0 2 2 2 0 AAA domain ATPase_2 PF01637.18 KFY03243.1 - 0.013 15.4 0.4 3.6 7.4 0.0 3.0 3 0 0 3 3 3 0 ATPase domain predominantly from Archaea Herpes_UL14 PF03580.14 KFY03243.1 - 0.066 13.5 2.8 0.15 12.3 2.8 1.6 1 0 0 1 1 1 0 Herpesvirus UL14-like protein AAA_16 PF13191.6 KFY03243.1 - 0.068 13.5 0.2 0.63 10.4 0.0 2.5 2 0 0 2 2 2 0 AAA ATPase domain ArgoL2 PF16488.5 KFY03243.1 - 0.13 12.7 0.2 0.29 11.5 0.2 1.7 1 0 0 1 1 1 0 Argonaute linker 2 domain CGI-121 PF08617.10 KFY03244.1 - 2.5e-53 180.5 0.0 4.5e-53 179.7 0.0 1.4 2 0 0 2 2 2 1 Kinase binding protein CGI-121 ORC3_N PF07034.11 KFY03244.1 - 0.027 13.6 0.4 0.034 13.2 0.4 1.2 1 0 0 1 1 1 0 Origin recognition complex (ORC) subunit 3 N-terminus HTH_40 PF14493.6 KFY03244.1 - 0.08 13.4 0.0 0.17 12.3 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain Fungal_trans PF04082.18 KFY03245.1 - 3.5e-19 68.9 0.1 5.8e-19 68.2 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KFY03245.1 - 4.9e-08 33.0 8.8 8.4e-08 32.2 8.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pro_dh PF01619.18 KFY03247.1 - 4.3e-18 65.9 0.6 4.7e-18 65.7 0.6 1.0 1 0 0 1 1 1 1 Proline dehydrogenase HMG_CoA_synt_C PF08540.10 KFY03255.1 - 2.3e-98 329.2 1.0 3.9e-98 328.5 1.0 1.3 1 1 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase C terminal HMG_CoA_synt_N PF01154.17 KFY03255.1 - 7.4e-79 263.6 0.1 1.1e-78 263.1 0.1 1.3 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase N terminal p450 PF00067.22 KFY03256.1 - 1e-62 212.4 0.0 1.2e-62 212.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 KFY03257.1 - 1.8e-25 89.7 0.0 3.4e-24 85.4 0.0 2.2 2 1 0 2 2 2 2 Cytochrome P450 Methyltransf_23 PF13489.6 KFY03262.1 - 1.2e-19 70.8 0.0 1.8e-19 70.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KFY03262.1 - 2.3e-14 53.8 0.0 6.3e-14 52.5 0.0 1.8 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KFY03262.1 - 3.5e-13 50.0 0.0 2.1e-12 47.5 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 KFY03262.1 - 3.3e-12 46.4 0.0 7.9e-11 42.0 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KFY03262.1 - 3.2e-10 40.6 0.0 4.8e-09 36.9 0.0 2.5 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_16 PF10294.9 KFY03262.1 - 0.0003 20.6 0.4 0.0055 16.5 0.1 2.4 2 1 0 2 2 2 1 Lysine methyltransferase MTS PF05175.14 KFY03262.1 - 0.00062 19.4 0.2 0.0013 18.3 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_4 PF02390.17 KFY03262.1 - 0.00091 18.7 0.0 0.0015 18.0 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_2 PF00891.18 KFY03262.1 - 0.0071 15.7 0.0 0.017 14.5 0.0 1.7 2 1 0 2 2 2 1 O-methyltransferase domain FtsJ PF01728.19 KFY03262.1 - 0.011 15.8 0.0 0.021 14.9 0.0 1.4 1 0 0 1 1 1 0 FtsJ-like methyltransferase Ubie_methyltran PF01209.18 KFY03262.1 - 0.02 14.2 0.0 0.11 11.8 0.0 1.9 2 0 0 2 2 2 0 ubiE/COQ5 methyltransferase family CMAS PF02353.20 KFY03262.1 - 0.029 13.6 0.0 0.064 12.5 0.0 1.4 1 1 0 1 1 1 0 Mycolic acid cyclopropane synthetase PrmA PF06325.13 KFY03262.1 - 0.034 13.5 0.0 0.059 12.7 0.0 1.4 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) UPF0146 PF03686.13 KFY03262.1 - 0.12 12.3 0.0 0.24 11.3 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0146) Pol_alpha_B_N PF08418.10 KFY03280.1 - 1e-83 281.1 0.1 1.3e-83 280.8 0.1 1.1 1 0 0 1 1 1 1 DNA polymerase alpha subunit B N-terminal DNA_pol_E_B PF04042.16 KFY03280.1 - 6.8e-07 28.8 0.0 1.1e-06 28.2 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B TRAPP PF04051.16 KFY03281.1 - 1.6e-40 138.2 0.0 2.5e-40 137.6 0.0 1.3 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component CRAL_TRIO PF00650.20 KFY03281.1 - 1.6e-39 135.2 0.0 2.4e-39 134.6 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 KFY03281.1 - 5.4e-14 52.1 0.0 1.3e-13 50.9 0.0 1.7 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.6 KFY03281.1 - 0.00018 21.7 0.0 0.00029 21.0 0.0 1.3 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain Apc13p PF05839.11 KFY03282.1 - 5.9e-32 109.7 0.7 9e-32 109.1 0.3 1.5 2 0 0 2 2 2 1 Apc13p protein zf-RING_2 PF13639.6 KFY03283.1 - 0.0017 18.7 1.0 0.0017 18.7 1.0 2.3 2 0 0 2 2 2 1 Ring finger domain FANCL_C PF11793.8 KFY03283.1 - 0.083 13.1 4.3 3.9 7.7 1.7 2.8 2 1 0 2 2 2 0 FANCL C-terminal domain Prok-RING_4 PF14447.6 KFY03283.1 - 0.086 12.7 1.0 13 5.7 0.1 2.7 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 KFY03283.1 - 0.28 11.3 1.6 0.78 9.8 1.6 1.8 1 0 0 1 1 1 0 RING-type zinc-finger Kinesin PF00225.23 KFY03284.1 - 1.8e-112 375.6 0.0 1.8e-112 375.6 0.0 1.5 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 KFY03284.1 - 4.3e-25 88.4 0.1 1.1e-24 87.1 0.1 1.7 1 0 0 1 1 1 1 Microtubule binding DUF87 PF01935.17 KFY03284.1 - 0.7 9.9 0.0 0.7 9.9 0.0 3.3 3 1 0 3 3 3 0 Helicase HerA, central domain YabA PF06156.13 KFY03284.1 - 1 10.0 11.0 3.9 8.1 0.1 4.0 3 1 2 5 5 5 0 Initiation control protein YabA DUF5094 PF17015.5 KFY03284.1 - 1.9 8.6 10.7 5.7 7.0 5.4 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF5094) Cnn_1N PF07989.11 KFY03284.1 - 2.9 8.1 7.6 0.84 9.8 0.3 3.2 2 2 0 2 2 2 0 Centrosomin N-terminal motif 1 OmpH PF03938.14 KFY03284.1 - 3 8.2 12.7 3.7 7.9 7.3 2.3 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) Fez1 PF06818.15 KFY03284.1 - 3.6 8.0 13.6 0.74 10.2 9.7 1.9 2 0 0 2 2 2 0 Fez1 PUL PF08324.11 KFY03285.1 - 1e-60 205.4 0.3 5.7e-60 202.9 0.3 1.9 2 0 0 2 2 2 1 PUL domain Peptidase_C97 PF05903.14 KFY03285.1 - 7.4e-34 116.8 0.0 1.1e-33 116.2 0.0 1.3 1 0 0 1 1 1 1 PPPDE putative peptidase domain Thioredoxin PF00085.20 KFY03285.1 - 2.1e-13 50.2 0.0 4e-13 49.2 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin TraF PF13728.6 KFY03285.1 - 0.00011 22.2 0.0 0.00018 21.4 0.0 1.3 1 0 0 1 1 1 1 F plasmid transfer operon protein OST3_OST6 PF04756.13 KFY03285.1 - 0.00044 19.7 0.0 0.00064 19.2 0.0 1.2 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin_2 PF13098.6 KFY03285.1 - 0.0037 17.7 0.8 0.029 14.8 0.6 2.3 2 1 0 2 2 2 1 Thioredoxin-like domain GDA1_CD39 PF01150.17 KFY03286.1 - 1.8e-96 323.4 0.0 2.2e-96 323.1 0.0 1.0 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family AAA_lid_2 PF17863.1 KFY03287.1 - 7e-08 32.2 0.0 1.9e-07 30.8 0.0 1.7 2 0 0 2 2 2 1 AAA lid domain VHS PF00790.19 KFY03288.1 - 2.4e-41 140.9 1.1 2.8e-40 137.4 0.0 2.4 2 0 0 2 2 2 1 VHS domain FYVE PF01363.21 KFY03288.1 - 1.6e-15 57.0 2.7 3.2e-15 56.0 2.7 1.5 1 0 0 1 1 1 1 FYVE zinc finger GAT PF03127.14 KFY03288.1 - 5.1e-05 23.5 0.0 0.00015 22.0 0.0 1.9 1 0 0 1 1 1 1 GAT domain UIM PF02809.20 KFY03288.1 - 8.3e-05 22.2 18.0 0.0075 16.1 1.7 3.5 3 0 0 3 3 3 2 Ubiquitin interaction motif OAD_gamma PF04277.13 KFY03288.1 - 8.5 7.1 5.6 2.2 8.9 0.9 2.6 2 0 0 2 2 2 0 Oxaloacetate decarboxylase, gamma chain NUDIX PF00293.28 KFY03289.1 - 4e-14 52.8 0.2 1.5e-13 50.9 0.1 2.0 1 1 1 2 2 2 1 NUDIX domain NUDIX_4 PF14815.6 KFY03289.1 - 0.0064 16.5 0.2 5.9 6.9 0.1 2.9 3 0 0 3 3 3 2 NUDIX domain Phage_XkdX PF09693.10 KFY03290.1 - 0.0031 17.5 0.0 0.0044 17.0 0.0 1.2 1 0 0 1 1 1 1 Phage uncharacterised protein (Phage_XkdX) FAM176 PF14851.6 KFY03290.1 - 0.15 11.7 0.9 0.16 11.6 0.9 1.1 1 0 0 1 1 1 0 FAM176 family AF-4 PF05110.13 KFY03290.1 - 0.61 8.1 6.3 0.52 8.3 6.3 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein Glyco_hydro_75 PF07335.11 KFY03291.1 - 3e-60 203.2 0.3 4.5e-60 202.6 0.3 1.3 1 0 0 1 1 1 1 Fungal chitosanase of glycosyl hydrolase group 75 CarbpepA_inh PF02977.15 KFY03291.1 - 0.86 9.4 26.2 3.9 7.4 8.4 3.0 1 1 1 2 2 2 0 Carboxypeptidase A inhibitor Kelch_1 PF01344.25 KFY03292.1 - 6.8e-39 131.2 8.2 9.7e-08 31.5 0.0 7.7 8 0 0 8 8 8 5 Kelch motif Kelch_6 PF13964.6 KFY03292.1 - 8.8e-32 108.4 14.6 3.9e-07 30.1 0.1 7.1 3 2 4 7 7 7 6 Kelch motif Kelch_3 PF13415.6 KFY03292.1 - 1.3e-20 73.2 15.3 5.3e-06 26.6 0.1 6.5 8 0 0 8 8 8 4 Galactose oxidase, central domain Kelch_4 PF13418.6 KFY03292.1 - 3e-19 68.8 17.2 2.1e-06 27.6 0.0 7.7 7 2 0 7 7 7 6 Galactose oxidase, central domain Kelch_5 PF13854.6 KFY03292.1 - 7.9e-18 64.0 5.2 0.0034 17.3 0.1 6.3 6 0 0 6 6 6 6 Kelch motif Kelch_2 PF07646.15 KFY03292.1 - 1.5e-16 59.6 4.1 0.0013 18.7 0.0 6.3 7 1 0 7 7 7 5 Kelch motif DUF1668 PF07893.13 KFY03292.1 - 8e-05 22.1 0.1 0.4 10.0 0.0 3.3 2 1 1 3 3 3 2 Protein of unknown function (DUF1668) YlaH PF14036.6 KFY03293.1 - 0.044 14.1 0.3 0.044 14.1 0.3 2.2 3 0 0 3 3 3 0 YlaH-like protein PALP PF00291.25 KFY03294.1 - 1.5e-62 211.7 3.5 2.8e-62 210.8 3.5 1.4 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Peptidase_M20 PF01546.28 KFY03294.1 - 1.6e-25 90.1 0.0 2.9e-25 89.2 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 KFY03294.1 - 3.3e-17 62.4 0.0 3.8e-15 55.7 0.0 2.5 2 0 0 2 2 2 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 KFY03294.1 - 0.00017 21.3 0.2 0.00039 20.2 0.2 1.6 1 0 0 1 1 1 1 Peptidase family M28 Clathrin-link PF09268.10 KFY03294.1 - 0.048 13.0 0.0 0.14 11.6 0.0 1.8 1 0 0 1 1 1 0 Clathrin, heavy-chain linker Fungal_trans_2 PF11951.8 KFY03295.1 - 3.4e-13 49.2 0.8 1.4e-12 47.1 0.8 1.8 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KFY03295.1 - 7.3e-07 29.2 13.5 1.2e-06 28.5 13.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Multi-haem_cyto PF13447.6 KFY03295.1 - 0.38 9.9 3.3 0.77 9.0 0.0 2.1 2 0 0 2 2 2 0 Seven times multi-haem cytochrome CxxCH zinc_ribbon_10 PF10058.9 KFY03297.1 - 6.9e-20 70.5 0.1 1.1e-19 69.8 0.1 1.4 1 0 0 1 1 1 1 Predicted integral membrane zinc-ribbon metal-binding protein HscB_4_cys PF18256.1 KFY03297.1 - 0.15 11.9 2.6 8.4 6.3 0.4 2.6 2 0 0 2 2 2 0 Co-chaperone HscB tetracysteine metal binding motif Ima1_N PF09779.9 KFY03297.1 - 0.37 11.6 4.1 1.2 10.0 0.1 2.7 1 1 2 3 3 3 0 Ima1 N-terminal domain DEAD PF00270.29 KFY03299.1 - 8.1e-15 55.0 0.0 2.1e-14 53.7 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase ResIII PF04851.15 KFY03299.1 - 3.2e-10 40.3 0.2 1.5e-09 38.1 0.0 2.1 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 KFY03299.1 - 1e-08 35.5 0.1 2.4e-08 34.3 0.1 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain PhoH PF02562.16 KFY03299.1 - 0.026 14.0 0.0 0.41 10.1 0.0 2.2 2 0 0 2 2 2 0 PhoH-like protein RMI1_N PF08585.12 KFY03299.1 - 0.15 11.8 1.3 0.39 10.5 0.8 1.9 2 0 0 2 2 2 0 RecQ mediated genome instability protein Abhydrolase_6 PF12697.7 KFY03303.1 - 6e-05 23.8 0.4 0.00012 22.7 0.4 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KFY03303.1 - 0.00013 21.7 0.1 0.00021 21.0 0.1 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KFY03303.1 - 0.076 12.3 0.0 0.27 10.5 0.0 1.8 2 0 0 2 2 2 0 Serine aminopeptidase, S33 Ser_hydrolase PF06821.13 KFY03303.1 - 0.087 12.7 0.0 0.19 11.6 0.0 1.6 2 0 0 2 2 2 0 Serine hydrolase GED PF02212.18 KFY03304.1 - 0.065 13.4 0.5 0.24 11.6 0.5 1.8 1 1 0 1 1 1 0 Dynamin GTPase effector domain Abhydrolase_6 PF12697.7 KFY03311.1 - 0.00026 21.7 0.1 0.00027 21.6 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KFY03311.1 - 0.0003 20.5 0.0 0.00044 20.0 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Ser_hydrolase PF06821.13 KFY03311.1 - 0.013 15.4 0.3 0.02 14.7 0.2 1.3 1 1 0 1 1 1 0 Serine hydrolase Hydrolase_4 PF12146.8 KFY03311.1 - 0.035 13.4 0.1 0.094 12.0 0.0 1.8 2 0 0 2 2 2 0 Serine aminopeptidase, S33 Abhydrolase_8 PF06259.12 KFY03311.1 - 0.15 11.7 0.1 0.23 11.1 0.1 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase LIDHydrolase PF10230.9 KFY03311.1 - 0.52 9.8 2.4 0.71 9.4 0.5 1.8 2 0 0 2 2 2 0 Lipid-droplet associated hydrolase Transferase PF02458.15 KFY03312.1 - 3.7e-11 42.3 0.0 6e-11 41.7 0.0 1.4 1 1 0 1 1 1 1 Transferase family Condensation PF00668.20 KFY03312.1 - 0.086 11.5 0.5 0.18 10.5 0.5 1.6 1 1 0 1 1 1 0 Condensation domain ZZ PF00569.17 KFY03314.1 - 2.2e-11 43.4 6.2 4e-11 42.6 6.2 1.4 1 0 0 1 1 1 1 Zinc finger, ZZ type EF-hand_1 PF00036.32 KFY03314.1 - 2.8e-07 29.6 12.1 6.4e-05 22.2 0.6 3.4 4 0 0 4 4 4 2 EF hand EF-hand_7 PF13499.6 KFY03314.1 - 4e-07 30.4 2.2 0.00036 20.9 0.4 2.9 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 KFY03314.1 - 8.9e-07 28.4 4.8 6.2e-05 22.6 0.9 3.0 2 0 0 2 2 2 2 EF-hand domain C1_2 PF03107.16 KFY03314.1 - 0.00073 19.8 2.2 0.0014 18.9 2.2 1.4 1 0 0 1 1 1 1 C1 domain Mu-transpos_C PF09299.11 KFY03314.1 - 0.0066 16.4 0.0 0.14 12.1 0.0 2.4 2 0 0 2 2 2 1 Mu transposase, C-terminal EF-hand_8 PF13833.6 KFY03314.1 - 0.013 15.3 1.2 0.87 9.5 0.2 2.8 2 0 0 2 2 2 0 EF-hand domain pair zf-B_box PF00643.24 KFY03314.1 - 0.044 13.9 5.0 0.097 12.8 5.0 1.5 1 0 0 1 1 1 0 B-box zinc finger EF-hand_5 PF13202.6 KFY03314.1 - 0.048 13.2 3.1 0.11 12.0 0.8 2.6 2 0 0 2 2 2 0 EF hand DUF2335 PF10097.9 KFY03314.1 - 0.077 13.0 0.1 0.23 11.4 0.1 1.8 1 0 0 1 1 1 0 Predicted membrane protein (DUF2335) Dockerin_1 PF00404.18 KFY03314.1 - 0.092 13.0 0.5 0.24 11.6 0.1 1.9 2 0 0 2 2 1 0 Dockerin type I domain GATA PF00320.27 KFY03314.1 - 7.6 6.2 6.3 2 8.1 0.1 3.0 2 1 0 2 2 2 0 GATA zinc finger Diphthamide_syn PF01866.17 KFY03317.1 - 2.6e-87 293.1 0.0 3.4e-87 292.7 0.0 1.1 1 0 0 1 1 1 1 Putative diphthamide synthesis protein Fn_bind PF02986.14 KFY03317.1 - 1.8 8.3 4.2 0.43 10.4 0.5 1.8 2 0 0 2 2 2 0 Fibronectin binding repeat RTA1 PF04479.13 KFY03318.1 - 2e-69 233.3 9.5 2e-69 233.3 9.5 1.5 2 0 0 2 2 2 1 RTA1 like protein Fungal_trans_2 PF11951.8 KFY03319.1 - 0.0015 17.4 0.2 0.0022 16.9 0.2 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KFY03319.1 - 0.0027 17.8 2.8 0.0055 16.8 2.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Prot_inhib_II PF02428.15 KFY03319.1 - 0.16 12.5 1.5 0.33 11.4 1.5 1.5 1 0 0 1 1 1 0 Potato type II proteinase inhibitor family Abhydrolase_1 PF00561.20 KFY03320.1 - 6.5e-14 52.2 0.0 4.1e-13 49.6 0.0 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KFY03320.1 - 3.6e-12 46.1 0.0 9.7e-11 41.4 0.0 2.1 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KFY03320.1 - 6.7e-11 43.2 0.4 6.7e-11 43.2 0.4 1.7 2 0 0 2 2 2 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 KFY03320.1 - 0.0018 17.8 0.6 0.29 10.6 0.0 2.6 3 0 0 3 3 3 2 Prolyl oligopeptidase family Glyco_hydro_43 PF04616.14 KFY03320.1 - 0.0087 15.4 0.9 0.015 14.6 0.9 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 Glyco_hydro_32N PF00251.20 KFY03320.1 - 0.013 15.0 0.0 0.025 14.1 0.0 1.4 1 0 0 1 1 1 0 Glycosyl hydrolases family 32 N-terminal domain UPF0227 PF05728.12 KFY03320.1 - 0.087 12.8 0.0 0.99 9.3 0.0 2.1 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0227) Abhydrolase_4 PF08386.10 KFY03320.1 - 0.11 12.6 0.0 0.22 11.7 0.0 1.5 1 0 0 1 1 1 0 TAP-like protein Thioesterase PF00975.20 KFY03320.1 - 0.11 12.6 0.0 0.22 11.6 0.0 1.4 1 0 0 1 1 1 0 Thioesterase domain EST1 PF10374.9 KFY03321.1 - 0.034 14.8 0.2 0.039 14.6 0.2 1.3 1 1 0 1 1 1 0 Telomerase activating protein Est1 Kelch_5 PF13854.6 KFY03322.1 - 2.2e-06 27.5 0.3 2.2e-06 27.5 0.3 4.2 4 0 0 4 4 4 2 Kelch motif VSP PF03302.13 KFY03322.1 - 0.15 10.9 0.1 0.24 10.2 0.1 1.2 1 0 0 1 1 1 0 Giardia variant-specific surface protein FAD_binding_4 PF01565.23 KFY03324.1 - 3.5e-23 81.9 0.0 5.4e-23 81.3 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 KFY03324.1 - 0.0061 16.6 0.1 0.024 14.7 0.1 2.1 1 0 0 1 1 1 1 Berberine and berberine like EstA_Ig_like PF18435.1 KFY03324.1 - 0.14 12.3 0.0 0.27 11.4 0.0 1.4 1 0 0 1 1 1 0 Esterase Ig-like N-terminal domain COesterase PF00135.28 KFY03325.1 - 1.5e-58 198.9 0.0 8.3e-58 196.5 0.0 1.8 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KFY03325.1 - 1.3e-07 31.7 0.0 2.6e-07 30.7 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KFY03325.1 - 0.036 13.5 0.0 0.063 12.8 0.0 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family Say1_Mug180 PF10340.9 KFY03325.1 - 0.1 11.4 0.0 0.54 9.1 0.0 1.9 2 0 0 2 2 2 0 Steryl acetyl hydrolase Fungal_trans_2 PF11951.8 KFY03326.1 - 2e-06 26.9 0.5 2.7e-06 26.4 0.5 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KFY03326.1 - 2.2e-05 24.5 9.7 2.2e-05 24.5 9.7 2.2 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF1175 PF06672.11 KFY03327.1 - 0.0011 18.7 0.1 0.0019 17.9 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1175) Glyco_hydro_43 PF04616.14 KFY03328.1 - 6.8e-67 225.8 0.7 8.5e-67 225.5 0.7 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 GH43_C2 PF17851.1 KFY03328.1 - 1.1e-16 61.1 0.0 1.7e-16 60.6 0.0 1.2 1 0 0 1 1 1 1 Beta xylosidase C-terminal Concanavalin A-like domain Gpr1_Fun34_YaaH PF01184.19 KFY03330.1 - 1.9e-92 308.5 21.0 2.3e-92 308.3 21.0 1.1 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family DUF2948 PF11164.8 KFY03330.1 - 0.1 12.6 0.2 0.28 11.2 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2948) DUF2748 PF10871.8 KFY03330.1 - 0.17 10.5 0.1 0.25 10.0 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2748) DUF202 PF02656.15 KFY03330.1 - 3.1 8.3 10.7 11 6.6 0.6 3.3 2 1 1 3 3 3 0 Domain of unknown function (DUF202) Glyco_hydro_61 PF03443.14 KFY03331.1 - 3e-55 187.3 0.0 3.6e-55 187.1 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 DAO PF01266.24 KFY03332.1 - 1.4e-29 103.9 0.3 1.5e-29 103.7 0.3 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KFY03332.1 - 9.7e-05 22.5 0.6 0.00026 21.1 0.6 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KFY03332.1 - 0.0002 20.7 0.0 0.00035 19.9 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KFY03332.1 - 0.00043 19.5 0.1 0.00068 18.8 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.27 KFY03332.1 - 0.0012 19.4 0.2 0.0032 18.0 0.2 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KFY03332.1 - 0.002 17.4 0.0 0.0041 16.4 0.0 1.4 1 0 0 1 1 1 1 Thi4 family GIDA PF01134.22 KFY03332.1 - 0.0026 16.9 0.2 0.0035 16.5 0.2 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A ApbA PF02558.16 KFY03332.1 - 0.005 16.5 0.2 0.0095 15.6 0.2 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA HI0933_like PF03486.14 KFY03332.1 - 0.012 14.3 0.2 0.017 13.8 0.2 1.1 1 0 0 1 1 1 0 HI0933-like protein 3HCDH_N PF02737.18 KFY03332.1 - 0.029 14.3 0.1 0.051 13.5 0.1 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_7 PF13241.6 KFY03332.1 - 0.029 14.8 0.0 0.052 14.0 0.0 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding Pyr_redox_3 PF13738.6 KFY03332.1 - 0.051 12.8 0.0 0.071 12.3 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 KFY03332.1 - 0.14 11.4 0.1 0.23 10.7 0.1 1.3 1 0 0 1 1 1 0 FAD binding domain SesA PF17107.5 KFY03334.1 - 2.9e-34 117.9 0.0 9.1e-34 116.3 0.0 2.0 1 0 0 1 1 1 1 N-terminal domain on NACHT_NTPase and P-loop NTPases TPR_12 PF13424.6 KFY03334.1 - 2.8e-18 66.0 0.1 8e-08 32.5 0.1 3.8 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_10 PF13374.6 KFY03334.1 - 1.6e-15 56.4 0.0 0.026 14.4 0.0 5.8 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_19 PF14559.6 KFY03334.1 - 0.00015 22.2 0.3 11 6.6 0.0 5.1 5 1 1 6 6 6 2 Tetratricopeptide repeat TPR_14 PF13428.6 KFY03334.1 - 0.00026 21.5 0.0 5.3 8.1 0.1 5.1 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_MalT PF17874.1 KFY03334.1 - 0.0011 18.5 0.2 0.003 17.0 0.1 1.7 2 0 0 2 2 2 1 MalT-like TPR region TPR_7 PF13176.6 KFY03334.1 - 0.017 15.1 0.0 1 9.5 0.0 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat AAA_16 PF13191.6 KFY03334.1 - 0.03 14.7 0.2 0.3 11.4 0.0 2.8 2 1 1 3 3 3 0 AAA ATPase domain TPR_6 PF13174.6 KFY03334.1 - 0.046 14.4 0.3 69 4.4 0.0 4.7 6 0 0 6 6 6 0 Tetratricopeptide repeat Abhydrolase_1 PF00561.20 KFY03336.1 - 1.7e-21 77.1 0.0 1.9e-20 73.6 0.0 2.1 1 1 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KFY03336.1 - 5.9e-15 56.5 0.0 8.2e-15 56.0 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KFY03336.1 - 7.2e-15 54.9 0.0 1.1e-14 54.3 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 DUF1057 PF06342.12 KFY03336.1 - 6e-06 25.5 0.0 8.3e-06 25.0 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1057) Ndr PF03096.14 KFY03336.1 - 1.1e-05 24.3 0.0 2.8e-05 23.0 0.0 1.6 2 0 0 2 2 2 1 Ndr family PGAP1 PF07819.13 KFY03336.1 - 0.00089 19.0 0.0 0.0013 18.5 0.0 1.2 1 0 0 1 1 1 1 PGAP1-like protein DUF915 PF06028.11 KFY03336.1 - 0.0022 17.3 0.0 0.0029 17.0 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF915) Abhydrolase_5 PF12695.7 KFY03336.1 - 0.044 13.6 0.0 0.16 11.8 0.0 1.8 2 0 0 2 2 2 0 Alpha/beta hydrolase family Thioesterase PF00975.20 KFY03336.1 - 0.065 13.3 0.0 0.1 12.7 0.0 1.2 1 0 0 1 1 1 0 Thioesterase domain Esterase PF00756.20 KFY03336.1 - 0.074 12.7 0.0 0.12 12.0 0.0 1.5 1 0 0 1 1 1 0 Putative esterase Lipase_3 PF01764.25 KFY03336.1 - 0.076 12.9 0.0 0.13 12.2 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) Abhydrolase_3 PF07859.13 KFY03336.1 - 0.077 12.8 0.0 0.12 12.2 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold BAAT_C PF08840.11 KFY03336.1 - 0.085 12.8 0.0 0.17 11.8 0.0 1.5 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal DLH PF01738.18 KFY03336.1 - 0.16 11.5 0.1 9.8 5.7 0.1 2.6 2 1 1 3 3 3 0 Dienelactone hydrolase family UPF0227 PF05728.12 KFY03336.1 - 0.2 11.6 0.0 0.31 11.0 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) MFS_1 PF07690.16 KFY03338.1 - 1.5e-36 126.1 36.4 1.2e-33 116.5 18.6 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KFY03338.1 - 4.8e-09 35.6 4.8 4.8e-09 35.6 4.8 1.7 2 0 0 2 2 2 1 Sugar (and other) transporter Sulfatase PF00884.23 KFY03339.1 - 3.8e-63 213.7 0.3 5.1e-63 213.3 0.3 1.2 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.22 KFY03339.1 - 0.084 12.4 1.5 9.6 5.7 0.2 2.5 3 0 0 3 3 3 0 Type I phosphodiesterase / nucleotide pyrophosphatase DUF4976 PF16347.5 KFY03339.1 - 0.089 13.1 0.0 0.2 12.0 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4976) dUTPase PF00692.19 KFY03340.1 - 2.9e-12 46.4 0.0 4.7e-12 45.7 0.0 1.3 1 0 0 1 1 1 1 dUTPase DCD PF06559.11 KFY03340.1 - 0.00019 20.3 0.0 0.00043 19.2 0.0 1.4 1 1 0 1 1 1 1 2'-deoxycytidine 5'-triphosphate deaminase (DCD) DUF4968 PF16338.5 KFY03342.1 - 5e-05 23.5 0.0 0.00011 22.5 0.0 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF4968) DUF4968 PF16338.5 KFY03344.1 - 0.00095 19.4 0.0 0.002 18.4 0.0 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF4968) HMG_box PF00505.19 KFY03345.1 - 0.0035 17.7 0.4 0.016 15.6 0.0 2.1 2 0 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KFY03345.1 - 0.037 14.6 0.2 0.16 12.6 0.0 2.0 1 1 1 2 2 2 0 HMG-box domain Ecl1 PF12855.7 KFY03346.1 - 1.6e-06 29.4 7.0 1.6e-06 29.4 7.0 2.0 2 1 0 2 2 2 1 ECL1/2/3 zinc binding proteins DUF3199 PF11436.8 KFY03347.1 - 0.11 12.5 0.0 0.17 11.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3199) RSN1_7TM PF02714.15 KFY03348.1 - 9.1e-54 182.6 16.4 6.2e-33 114.3 7.7 2.2 2 0 0 2 2 2 2 Calcium-dependent channel, 7TM region, putative phosphate PHM7_ext PF12621.8 KFY03348.1 - 2.8e-11 43.4 0.0 4.8e-11 42.7 0.0 1.4 1 0 0 1 1 1 1 Extracellular tail, of 10TM putative phosphate transporter AA_permease_2 PF13520.6 KFY03350.1 - 1.5e-34 119.6 52.7 2.2e-34 119.0 52.7 1.2 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KFY03350.1 - 5.6e-15 54.9 44.9 8.2e-15 54.3 44.9 1.2 1 0 0 1 1 1 1 Amino acid permease Glyco_hydro_16 PF00722.21 KFY03350.1 - 1.3e-06 28.0 0.0 2.9e-06 26.9 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 PhyH PF05721.13 KFY03352.1 - 1.4e-27 97.4 0.0 2.4e-27 96.6 0.0 1.4 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) Fungal_trans_2 PF11951.8 KFY03355.1 - 2.9e-06 26.3 1.3 2.9e-06 26.3 1.3 2.1 1 1 1 2 2 2 2 Fungal specific transcription factor domain Amidohydro_1 PF01979.20 KFY03356.1 - 3.8e-26 92.2 0.0 5e-26 91.8 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 KFY03356.1 - 2.6e-11 43.7 0.1 2.2e-05 24.1 0.0 2.2 2 0 0 2 2 2 2 Amidohydrolase family Cu_amine_oxid PF01179.20 KFY03357.1 - 1.8e-161 537.6 0.0 2.2e-161 537.4 0.0 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN2 PF02727.16 KFY03357.1 - 2.7e-10 40.4 0.0 6.1e-10 39.2 0.0 1.6 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain Cu_amine_oxidN3 PF02728.16 KFY03357.1 - 5e-05 23.6 0.0 0.00013 22.3 0.0 1.6 1 0 0 1 1 1 1 Copper amine oxidase, N3 domain Abhydrolase_6 PF12697.7 KFY03369.1 - 7.4e-12 46.3 2.1 9.3e-12 46.0 1.4 1.5 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KFY03369.1 - 8.8e-10 38.6 0.6 4.6e-09 36.3 0.3 2.0 2 0 0 2 2 2 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KFY03369.1 - 2.7e-08 33.6 0.0 6.4e-08 32.3 0.0 1.6 1 0 0 1 1 1 1 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 KFY03369.1 - 1.5e-07 30.9 0.4 1.6e-06 27.6 0.3 2.0 1 1 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_3 PF07859.13 KFY03369.1 - 0.00011 22.1 0.0 0.00017 21.5 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S15 PF02129.18 KFY03369.1 - 0.0044 16.6 5.3 0.0072 16.0 1.9 2.1 1 1 1 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) Ser_hydrolase PF06821.13 KFY03369.1 - 0.012 15.5 0.3 0.025 14.4 0.3 1.5 1 0 0 1 1 1 0 Serine hydrolase DUF1072 PF06380.11 KFY03369.1 - 0.02 14.8 0.2 0.05 13.5 0.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1072) AbrB PF05145.12 KFY03369.1 - 0.056 12.4 3.3 0.1 11.6 3.3 1.3 1 0 0 1 1 1 0 Transition state regulatory protein AbrB Abhydrolase_2 PF02230.16 KFY03369.1 - 0.065 13.0 0.1 0.98 9.2 0.1 2.4 3 0 0 3 3 3 0 Phospholipase/Carboxylesterase Lipase_3 PF01764.25 KFY03369.1 - 0.085 12.7 0.2 0.22 11.4 0.2 1.6 1 0 0 1 1 1 0 Lipase (class 3) TPPK_C PF12555.8 KFY03369.1 - 0.091 12.8 0.8 1.7 8.8 0.0 2.8 2 0 0 2 2 2 0 Thiamine pyrophosphokinase C terminal DUF676 PF05057.14 KFY03369.1 - 0.098 12.1 0.1 0.19 11.2 0.1 1.4 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Abhydrolase_5 PF12695.7 KFY03369.1 - 0.13 12.0 0.0 0.69 9.7 0.1 1.9 2 0 0 2 2 2 0 Alpha/beta hydrolase family NMT_C PF02799.15 KFY03370.1 - 3.8e-88 294.5 0.0 5.6e-88 293.9 0.0 1.2 1 0 0 1 1 1 1 Myristoyl-CoA:protein N-myristoyltransferase, C-terminal domain NMT PF01233.19 KFY03370.1 - 1.1e-73 246.3 0.0 2.3e-73 245.3 0.0 1.5 1 0 0 1 1 1 1 Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain Molydop_binding PF01568.21 KFY03370.1 - 0.023 14.7 0.0 0.049 13.6 0.0 1.5 1 0 0 1 1 1 0 Molydopterin dinucleotide binding domain NTP_transf_9 PF04248.12 KFY03370.1 - 0.037 13.9 0.0 0.075 12.9 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF427) RhoGAP PF00620.27 KFY03370.1 - 0.075 12.9 0.0 0.14 12.0 0.0 1.4 1 0 0 1 1 1 0 RhoGAP domain Dynamin_M PF01031.20 KFY03378.1 - 3.8e-21 75.5 0.0 8.3e-21 74.4 0.0 1.5 1 0 0 1 1 1 1 Dynamin central region Dynamin_N PF00350.23 KFY03378.1 - 1.8e-19 70.4 0.4 4e-19 69.3 0.4 1.6 1 0 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.23 KFY03378.1 - 1.8e-07 31.2 0.9 2.4e-06 27.6 0.9 2.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 KFY03378.1 - 1.5e-05 24.6 0.0 0.0011 18.5 0.0 2.5 2 0 0 2 2 2 1 Ferrous iron transport protein B Roc PF08477.13 KFY03378.1 - 0.0034 17.6 0.0 1.3 9.3 0.0 3.0 2 1 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 KFY03378.1 - 0.091 12.4 0.2 0.98 9.0 0.0 2.4 2 0 0 2 2 2 0 Ras family GED PF02212.18 KFY03378.1 - 0.091 12.9 0.0 0.38 10.9 0.0 2.2 1 0 0 1 1 1 0 Dynamin GTPase effector domain GTP_EFTU PF00009.27 KFY03378.1 - 0.13 11.7 1.5 0.59 9.6 1.1 2.3 3 1 0 3 3 3 0 Elongation factor Tu GTP binding domain GYF_2 PF14237.6 KFY03378.1 - 0.16 11.8 0.1 0.42 10.5 0.1 1.7 1 0 0 1 1 1 0 GYF domain 2 Arf PF00025.21 KFY03378.1 - 0.16 11.4 2.4 0.23 10.9 0.3 2.3 3 1 0 3 3 3 0 ADP-ribosylation factor family Glyco_hydro_4 PF02056.16 KFY03379.1 - 0.031 13.8 0.4 0.042 13.4 0.4 1.2 1 0 0 1 1 1 0 Family 4 glycosyl hydrolase Asn_synthase PF00733.21 KFY03381.1 - 2.5e-94 316.8 0.1 1.2e-55 189.6 0.0 2.1 1 1 1 2 2 2 2 Asparagine synthase UQ_con PF00179.26 KFY03381.1 - 6.2e-48 162.0 0.1 1.3e-47 160.9 0.0 1.6 2 0 0 2 2 2 1 Ubiquitin-conjugating enzyme GATase_7 PF13537.6 KFY03381.1 - 6e-36 123.1 0.0 1.3e-35 122.0 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.6 KFY03381.1 - 9.2e-28 97.1 0.0 6.1e-27 94.4 0.0 2.0 2 0 0 2 2 2 1 Glutamine amidotransferase domain DUF3700 PF12481.8 KFY03381.1 - 9.2e-09 35.1 0.0 1.5e-08 34.4 0.0 1.3 1 0 0 1 1 1 1 Aluminium induced protein NAD_synthase PF02540.17 KFY03381.1 - 0.0057 15.8 0.0 0.013 14.6 0.0 1.6 1 1 0 1 1 1 1 NAD synthase Prok-E2_B PF14461.6 KFY03381.1 - 0.0076 16.0 0.0 0.015 15.0 0.0 1.4 1 0 0 1 1 1 1 Prokaryotic E2 family B IBR PF01485.21 KFY03382.1 - 2.3e-09 37.3 55.8 2.1e-05 24.7 1.6 5.9 5 2 0 5 5 5 3 IBR domain, a half RING-finger domain zf-RING_2 PF13639.6 KFY03382.1 - 0.0057 17.0 4.1 0.0057 17.0 4.1 7.1 7 1 1 8 8 8 1 Ring finger domain Fer2_3 PF13085.6 KFY03382.1 - 0.054 13.5 0.8 0.054 13.5 0.8 3.0 3 1 1 4 4 4 0 2Fe-2S iron-sulfur cluster binding domain DUF1712 PF08217.11 KFY03383.1 - 3.1e-15 55.7 0.0 4.5e-14 51.9 0.0 2.1 2 0 0 2 2 2 2 Fungal domain of unknown function (DUF1712) Formyl_trans_N PF00551.19 KFY03384.1 - 6.6e-22 78.1 0.0 1e-21 77.5 0.0 1.3 1 0 0 1 1 1 1 Formyl transferase WD40 PF00400.32 KFY03385.1 - 5.1e-41 137.9 24.2 4.1e-10 40.1 0.0 8.0 8 0 0 8 8 8 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFY03385.1 - 1.2e-12 47.9 1.5 0.003 17.8 0.1 5.2 2 1 3 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 KFY03385.1 - 5.5e-08 32.1 0.1 0.2 10.6 0.0 4.5 2 1 2 4 4 4 3 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 KFY03385.1 - 4.4e-07 28.9 3.8 0.021 13.5 0.1 4.6 4 1 1 5 5 5 3 Nucleoporin Nup120/160 PALB2_WD40 PF16756.5 KFY03385.1 - 2.4e-06 26.7 0.1 2.4e-06 26.7 0.1 2.9 4 1 1 5 5 5 1 Partner and localizer of BRCA2 WD40 domain Frtz PF11768.8 KFY03385.1 - 0.00091 17.7 0.0 0.0017 16.8 0.0 1.4 1 0 0 1 1 1 1 WD repeat-containing and planar cell polarity effector protein Fritz HPS3_N PF14761.6 KFY03385.1 - 0.0081 15.7 0.0 0.027 14.0 0.0 1.9 1 1 1 2 2 2 1 Hermansky-Pudlak syndrome 3 Coatomer_WDAD PF04053.14 KFY03385.1 - 0.014 14.5 0.0 0.018 14.1 0.0 1.2 1 0 0 1 1 1 0 Coatomer WD associated region Hira PF07569.11 KFY03385.1 - 0.051 13.3 0.6 1 9.1 0.5 2.9 1 1 1 2 2 2 0 TUP1-like enhancer of split CPSF_A PF03178.15 KFY03385.1 - 0.081 12.2 0.0 0.38 10.0 0.0 1.9 2 0 0 2 2 2 0 CPSF A subunit region Spc7 PF08317.11 KFY03386.1 - 0.0077 15.1 0.1 0.015 14.2 0.1 1.4 1 0 0 1 1 1 1 Spc7 kinetochore protein HIP1_clath_bdg PF16515.5 KFY03386.1 - 0.066 13.8 4.1 0.39 11.3 0.2 2.6 2 0 0 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 BLOC1_2 PF10046.9 KFY03386.1 - 0.18 12.2 0.4 0.36 11.1 0.4 1.4 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF3450 PF11932.8 KFY03386.1 - 0.19 11.0 0.4 0.46 9.7 0.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) TACC_C PF05010.14 KFY03386.1 - 0.19 11.5 2.5 0.17 11.6 0.7 1.7 2 0 0 2 2 2 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal GAS PF13851.6 KFY03386.1 - 0.27 10.5 3.9 0.07 12.5 0.5 1.6 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding betaPIX_CC PF16523.5 KFY03386.1 - 0.33 10.8 1.4 21 5.0 0.1 2.7 1 1 1 2 2 2 0 betaPIX coiled coil TMF_TATA_bd PF12325.8 KFY03386.1 - 0.4 10.9 2.7 0.58 10.4 0.2 2.2 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding Ly49 PF08391.10 KFY03386.1 - 1.8 8.9 6.3 0.21 12.0 1.7 1.8 2 0 0 2 2 1 0 Ly49-like protein, N-terminal region UPF0242 PF06785.11 KFY03386.1 - 3.2 7.8 4.4 0.62 10.1 0.4 1.7 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus KLRAQ PF10205.9 KFY03386.1 - 4.1 7.7 7.5 20 5.5 0.0 3.0 3 0 0 3 3 3 0 Predicted coiled-coil domain-containing protein SUR7 PF06687.12 KFY03388.1 - 4.6e-26 91.8 12.7 5.7e-26 91.5 12.7 1.1 1 0 0 1 1 1 1 SUR7/PalI family AAA_16 PF13191.6 KFY03389.1 - 4.1e-07 30.5 0.0 1.3e-06 28.9 0.0 1.9 1 1 0 1 1 1 1 AAA ATPase domain NACHT PF05729.12 KFY03389.1 - 3e-06 27.3 0.0 7.9e-06 25.9 0.0 1.7 1 1 0 1 1 1 1 NACHT domain NTPase_1 PF03266.15 KFY03389.1 - 1.6e-05 24.9 0.0 3.7e-05 23.7 0.0 1.7 2 0 0 2 2 2 1 NTPase AAA_22 PF13401.6 KFY03389.1 - 0.001 19.3 0.0 0.0024 18.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain APS_kinase PF01583.20 KFY03389.1 - 0.0041 17.0 0.0 0.02 14.8 0.0 2.0 2 0 0 2 2 2 1 Adenylylsulphate kinase AAA_5 PF07728.14 KFY03389.1 - 0.0075 16.3 0.1 0.13 12.2 0.1 2.3 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) MeaB PF03308.16 KFY03389.1 - 0.012 14.6 0.0 0.022 13.8 0.0 1.3 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_33 PF13671.6 KFY03389.1 - 0.013 15.6 0.0 0.028 14.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain ATPase_2 PF01637.18 KFY03389.1 - 0.026 14.5 0.0 0.047 13.6 0.0 1.3 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea cobW PF02492.19 KFY03389.1 - 0.038 13.6 0.0 0.39 10.3 0.0 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain KTI12 PF08433.10 KFY03389.1 - 0.04 13.4 0.0 0.063 12.7 0.0 1.3 1 0 0 1 1 1 0 Chromatin associated protein KTI12 MobB PF03205.14 KFY03389.1 - 0.066 13.1 0.0 0.13 12.1 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_14 PF13173.6 KFY03389.1 - 0.085 12.9 0.0 0.19 11.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.6 KFY03389.1 - 0.092 13.1 0.0 0.22 11.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 KFY03389.1 - 0.1 13.1 0.0 0.27 11.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain Lipase_GDSL_3 PF14606.6 KFY03389.1 - 0.14 12.3 0.0 0.27 11.4 0.0 1.4 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase family UFD1 PF03152.14 KFY03390.1 - 7.3e-29 100.4 0.0 1.1e-22 80.4 0.0 3.9 3 1 0 3 3 3 2 Ubiquitin fusion degradation protein UFD1 AZUL PF16558.5 KFY03390.1 - 5.6e-05 23.3 0.9 0.00027 21.1 0.1 2.7 2 0 0 2 2 2 1 Amino-terminal Zinc-binding domain of ubiquitin ligase E3A Methyltransf_22 PF13383.6 KFY03391.1 - 2.5e-17 63.3 0.0 3.3e-17 62.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_21 PF05050.12 KFY03391.1 - 1.7e-06 28.2 0.0 2.2e-06 27.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase FkbM domain BTRD1 PF17660.1 KFY03391.1 - 0.068 13.0 0.0 0.8 9.6 0.0 2.2 2 0 0 2 2 2 0 Bacterial tandem repeat domain 1 GCIP PF13324.6 KFY03392.1 - 7.3e-21 74.9 0.1 1.5e-20 73.9 0.1 1.4 1 1 0 1 1 1 1 Grap2 and cyclin-D-interacting Actin PF00022.19 KFY03393.1 - 3.2e-99 332.3 0.0 3e-98 329.1 0.0 1.9 1 1 0 1 1 1 1 Actin BPL_N PF09825.9 KFY03394.1 - 1.8e-144 481.5 0.0 2.4e-144 481.1 0.0 1.2 1 0 0 1 1 1 1 Biotin-protein ligase, N terminal BPL_LplA_LipB PF03099.19 KFY03394.1 - 2.9e-25 88.7 0.1 4.8e-25 88.0 0.1 1.4 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family BPL_C PF02237.17 KFY03394.1 - 0.0046 16.8 0.1 0.012 15.5 0.1 1.8 1 0 0 1 1 1 1 Biotin protein ligase C terminal domain DUF2250 PF10007.9 KFY03394.1 - 0.087 12.9 0.0 0.25 11.5 0.0 1.7 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2250) Rtf2 PF04641.12 KFY03397.1 - 6.3e-55 186.4 1.3 7.4e-55 186.1 1.3 1.1 1 0 0 1 1 1 1 Rtf2 RING-finger zf-Nse PF11789.8 KFY03397.1 - 3.6e-05 23.5 0.2 0.014 15.2 0.0 2.6 2 0 0 2 2 2 2 Zinc-finger of the MIZ type in Nse subunit zf-RING_5 PF14634.6 KFY03397.1 - 0.12 12.4 0.1 0.25 11.4 0.1 1.6 1 0 0 1 1 1 0 zinc-RING finger domain zf-NOSIP PF15906.5 KFY03397.1 - 0.16 12.1 0.0 0.31 11.2 0.0 1.5 1 0 0 1 1 1 0 Zinc-finger of nitric oxide synthase-interacting protein FAT PF02259.23 KFY03398.1 - 2.8e-131 437.8 1.5 2.8e-131 437.8 1.5 2.1 2 0 0 2 2 2 1 FAT domain DUF3385 PF11865.8 KFY03398.1 - 3.5e-77 257.8 7.4 2e-68 229.4 1.8 5.2 4 1 1 5 5 5 3 Domain of unknown function (DUF3385) PI3_PI4_kinase PF00454.27 KFY03398.1 - 6.4e-71 239.1 0.1 1.1e-70 238.3 0.1 1.4 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FRB_dom PF08771.11 KFY03398.1 - 3.5e-44 149.2 1.9 1.1e-43 147.6 0.1 2.9 2 0 0 2 2 2 1 FKBP12-rapamycin binding domain HEAT PF02985.22 KFY03398.1 - 2.9e-19 67.5 11.0 3.2e-05 23.8 0.0 11.7 12 0 0 12 12 11 2 HEAT repeat HEAT_2 PF13646.6 KFY03398.1 - 1.7e-15 57.1 16.9 0.0009 19.6 0.1 8.9 9 1 0 9 9 7 3 HEAT repeats HEAT_EZ PF13513.6 KFY03398.1 - 1.8e-11 44.3 16.2 0.00023 21.6 0.0 9.8 9 3 3 12 12 9 3 HEAT-like repeat FATC PF02260.20 KFY03398.1 - 2.7e-11 43.1 0.2 8.3e-11 41.5 0.2 1.9 1 0 0 1 1 1 1 FATC domain Cnd1 PF12717.7 KFY03398.1 - 1e-07 32.1 1.5 0.0043 17.1 0.0 5.9 4 1 2 6 6 6 2 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.7 KFY03398.1 - 1.4e-07 32.0 1.8 22 5.7 0.0 7.5 7 1 1 8 8 7 0 Vacuolar 14 Fab1-binding region Adaptin_N PF01602.20 KFY03398.1 - 4.1e-06 25.7 9.6 0.0015 17.1 1.0 4.9 3 1 1 4 4 4 1 Adaptin N terminal region CLASP_N PF12348.8 KFY03398.1 - 1.4e-05 24.7 2.4 0.22 11.1 0.0 5.4 5 1 0 5 5 5 1 CLASP N terminal IFRD PF05004.13 KFY03398.1 - 0.00014 21.1 0.0 0.64 9.1 0.0 4.0 3 1 0 4 4 4 1 Interferon-related developmental regulator (IFRD) MMS19_C PF12460.8 KFY03398.1 - 0.0016 17.7 3.3 0.066 12.3 0.1 3.6 2 2 0 2 2 2 1 RNAPII transcription regulator C-terminal TPR_19 PF14559.6 KFY03398.1 - 0.015 15.8 3.2 43 4.7 0.0 5.3 4 0 0 4 4 4 0 Tetratricopeptide repeat ANAPC3 PF12895.7 KFY03398.1 - 0.017 15.3 5.2 13 6.1 1.0 4.7 4 1 1 5 5 4 0 Anaphase-promoting complex, cyclosome, subunit 3 DRIM PF07539.12 KFY03398.1 - 0.02 13.2 0.9 1.4 7.1 0.1 3.1 2 1 0 3 3 3 0 Down-regulated in metastasis DUF3730 PF12530.8 KFY03398.1 - 0.021 14.4 0.0 1.2 8.7 0.0 3.3 2 1 1 3 3 3 0 Protein of unknown function (DUF3730) VirDNA-topo-I_N PF09266.10 KFY03398.1 - 0.1 12.7 0.1 0.26 11.5 0.1 1.7 1 0 0 1 1 1 0 Viral DNA topoisomerase I, N-terminal TPR_7 PF13176.6 KFY03398.1 - 0.13 12.3 3.8 8.6 6.7 0.2 4.7 3 1 1 4 4 4 0 Tetratricopeptide repeat Tti2 PF10521.9 KFY03398.1 - 0.15 11.6 3.2 3.2 7.2 0.8 3.4 3 0 0 3 3 3 0 Tti2 family Sec7_N PF12783.7 KFY03398.1 - 0.42 10.5 11.0 1.6 8.6 0.0 5.2 6 1 0 6 6 5 0 Guanine nucleotide exchange factor in Golgi transport N-terminal TPR_14 PF13428.6 KFY03398.1 - 1.3 10.0 5.9 10 7.2 0.3 4.4 3 1 1 4 4 3 0 Tetratricopeptide repeat Aldo_ket_red PF00248.21 KFY03399.1 - 3.5e-61 207.0 0.0 4.3e-61 206.7 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Pex24p PF06398.11 KFY03401.1 - 9.7e-96 320.9 0.3 1.1e-95 320.7 0.3 1.0 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin Syntaxin-18_N PF10496.9 KFY03401.1 - 0.15 12.3 0.1 0.33 11.2 0.1 1.5 1 0 0 1 1 1 0 SNARE-complex protein Syntaxin-18 N-terminus PAP_assoc PF03828.19 KFY03402.1 - 4.7e-11 42.7 0.0 1.4e-10 41.2 0.0 1.9 2 0 0 2 2 2 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.23 KFY03402.1 - 4.2e-07 30.2 0.0 9.3e-07 29.1 0.0 1.6 1 0 0 1 1 1 1 Nucleotidyltransferase domain LsmAD PF06741.13 KFY03403.1 - 9e-27 93.4 4.3 9e-27 93.4 4.3 2.4 2 0 0 2 2 2 1 LsmAD domain DUF3018 PF11455.8 KFY03403.1 - 0.95 9.4 4.0 15 5.6 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3018) AIP3 PF03915.13 KFY03405.1 - 7.4e-159 529.2 2.0 7.4e-159 529.2 2.0 1.7 2 0 0 2 2 2 1 Actin interacting protein 3 PPI_Ypi1 PF07491.11 KFY03405.1 - 8.6e-24 83.1 0.9 3e-23 81.4 0.9 2.0 1 0 0 1 1 1 1 Protein phosphatase inhibitor Lectin_N PF03954.14 KFY03405.1 - 0.45 10.3 3.2 0.37 10.5 0.1 2.4 3 0 0 3 3 3 0 Hepatic lectin, N-terminal domain DivIC PF04977.15 KFY03405.1 - 5.6 6.8 5.7 7.6 6.4 0.0 3.3 3 0 0 3 3 3 0 Septum formation initiator HbrB PF08539.11 KFY03406.1 - 6.6e-49 166.1 0.0 1.7e-48 164.8 0.0 1.8 1 0 0 1 1 1 1 HbrB-like Gon7 PF08738.10 KFY03407.1 - 3.2e-10 40.1 2.0 3.2e-10 40.1 2.0 1.8 1 1 1 2 2 2 1 Gon7 family Vps39_1 PF10366.9 KFY03408.1 - 4.8e-35 120.1 0.0 7.7e-34 116.2 0.0 3.0 4 0 0 4 4 4 1 Vacuolar sorting protein 39 domain 1 Vps39_2 PF10367.9 KFY03408.1 - 3.4e-29 101.5 0.0 1.2e-28 99.7 0.0 2.0 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 2 CNH PF00780.22 KFY03408.1 - 5.2e-14 52.5 0.0 5.7e-13 49.1 0.0 2.1 1 1 0 1 1 1 1 CNH domain Clathrin PF00637.20 KFY03408.1 - 0.00013 21.9 1.5 0.0006 19.7 0.3 2.7 2 0 0 2 2 2 1 Region in Clathrin and VPS TPR_1 PF00515.28 KFY03408.1 - 0.0013 18.5 2.6 2.3 8.2 0.1 5.0 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_19 PF14559.6 KFY03408.1 - 0.056 14.0 1.2 13 6.4 0.2 4.0 2 2 1 4 4 4 0 Tetratricopeptide repeat TPR_12 PF13424.6 KFY03408.1 - 0.15 12.4 1.7 50 4.3 0.2 3.8 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_16 PF13432.6 KFY03408.1 - 0.21 12.3 0.3 7.2 7.3 0.2 2.8 1 1 0 1 1 1 0 Tetratricopeptide repeat ANAPC3 PF12895.7 KFY03408.1 - 0.5 10.6 2.4 6.8 7.0 0.1 3.5 3 2 1 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 LIM_bind PF01803.16 KFY03409.1 - 3.4e-74 249.4 0.2 3.4e-74 249.4 0.2 5.5 3 1 2 5 5 5 1 LIM-domain binding protein Abhydrolase_3 PF07859.13 KFY03410.1 - 1.9e-35 122.6 0.0 1.7e-24 86.9 0.0 2.4 1 1 0 2 2 2 2 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 KFY03410.1 - 0.026 13.4 0.0 0.042 12.7 0.0 1.2 1 0 0 1 1 1 0 Steryl acetyl hydrolase GET2 PF08690.10 KFY03411.1 - 1.7e-32 113.4 0.0 9.9e-32 110.8 0.0 1.9 1 1 0 1 1 1 1 GET complex subunit GET2 TRAM_LAG1_CLN8 PF03798.16 KFY03411.1 - 0.092 12.5 0.1 0.092 12.5 0.1 1.4 2 0 0 2 2 2 0 TLC domain Aminotran_1_2 PF00155.21 KFY03414.1 - 7.3e-35 120.8 0.0 8.9e-35 120.5 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 KFY03414.1 - 0.011 14.3 0.0 0.022 13.3 0.0 1.4 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme Glyco_hydro_17 PF00332.18 KFY03415.1 - 1.2e-10 41.5 3.0 8.4e-08 32.2 0.9 2.2 1 1 1 2 2 2 2 Glycosyl hydrolases family 17 Bromodomain PF00439.25 KFY03416.1 - 1.6e-37 127.4 3.4 5.8e-20 71.2 0.3 2.6 2 0 0 2 2 2 2 Bromodomain BAH PF01426.18 KFY03416.1 - 5.8e-16 58.5 0.9 5.8e-16 58.5 0.9 2.1 2 0 0 2 2 2 1 BAH domain AT_hook PF02178.19 KFY03416.1 - 2.2 8.4 8.9 0.17 11.9 1.2 3.3 2 0 0 2 2 2 0 AT hook motif HIT PF01230.23 KFY03418.1 - 3.3e-22 79.1 0.1 4.5e-22 78.6 0.1 1.2 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.8 KFY03418.1 - 6e-12 46.0 0.0 9.6e-12 45.4 0.0 1.3 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding CwfJ_C_1 PF04677.15 KFY03418.1 - 2.1e-05 24.4 0.0 2.8e-05 24.0 0.0 1.2 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 CRAL_TRIO PF00650.20 KFY03419.1 - 2.4e-39 134.6 0.0 4.1e-39 133.9 0.0 1.4 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 KFY03419.1 - 1.4e-13 50.8 0.1 3.4e-13 49.6 0.1 1.7 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.6 KFY03419.1 - 4.8e-07 30.0 0.0 1.2e-06 28.7 0.0 1.7 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain DASH_Dam1 PF08653.10 KFY03420.1 - 0.008 16.0 1.4 0.01 15.6 0.5 1.6 2 0 0 2 2 2 1 DASH complex subunit Dam1 INO80_Ies4 PF08193.11 KFY03420.1 - 0.01 15.8 1.6 0.011 15.7 1.6 1.1 1 0 0 1 1 1 0 INO80 complex subunit Ies4 zf-C2H2_jaz PF12171.8 KFY03421.1 - 2.2e-11 43.7 1.3 5.2e-11 42.5 1.3 1.7 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-U1 PF06220.12 KFY03421.1 - 0.0015 18.3 0.2 0.0043 16.8 0.2 1.8 1 0 0 1 1 1 1 U1 zinc finger zf-C2H2_2 PF12756.7 KFY03421.1 - 0.0032 17.8 0.6 0.0065 16.8 0.6 1.5 1 1 0 1 1 1 1 C2H2 type zinc-finger (2 copies) zf-met PF12874.7 KFY03421.1 - 0.015 15.7 1.0 0.042 14.3 1.0 1.8 1 0 0 1 1 1 0 Zinc-finger of C2H2 type Papo_T_antigen PF02380.15 KFY03421.1 - 0.45 10.7 0.0 0.45 10.7 0.0 2.0 2 1 1 3 3 3 0 T-antigen specific domain zf-LYAR PF08790.11 KFY03421.1 - 0.56 10.2 0.1 0.56 10.2 0.1 2.4 2 0 0 2 2 2 0 LYAR-type C2HC zinc finger Aconitase PF00330.20 KFY03422.1 - 3.1e-150 501.2 0.0 3.9e-150 500.9 0.0 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 KFY03422.1 - 1.3e-43 148.5 0.0 2.5e-43 147.5 0.0 1.5 1 0 0 1 1 1 1 Aconitase C-terminal domain Rhomboid PF01694.22 KFY03423.1 - 5.2e-15 55.8 9.2 5.2e-15 55.8 9.2 1.7 2 0 0 2 2 2 1 Rhomboid family DUF2070 PF09843.9 KFY03423.1 - 0.36 9.1 10.4 0.44 8.8 10.4 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) COPI_assoc PF08507.10 KFY03423.1 - 2.5 8.2 6.8 1.6 8.8 1.2 2.7 2 1 1 3 3 3 0 COPI associated protein Gaa1 PF04114.14 KFY03424.1 - 4e-173 577.0 4.2 4.9e-173 576.7 4.2 1.1 1 0 0 1 1 1 1 Gaa1-like, GPI transamidase component Phage_holin_3_2 PF04550.12 KFY03424.1 - 0.19 12.3 0.5 2.6 8.6 0.1 2.7 2 0 0 2 2 2 0 Phage holin family 2 PCI PF01399.27 KFY03425.1 - 8.9e-09 35.8 0.0 1.9e-08 34.8 0.0 1.6 1 0 0 1 1 1 1 PCI domain Rpn9_C PF18261.1 KFY03425.1 - 0.00086 18.8 1.1 0.0017 17.9 1.1 1.5 1 0 0 1 1 1 1 Rpn9 C-terminal helix Dam PF05869.11 KFY03425.1 - 0.038 13.6 0.1 0.19 11.3 0.0 2.1 3 0 0 3 3 3 0 DNA N-6-adenine-methyltransferase (Dam) N6-adenineMlase PF10237.9 KFY03426.1 - 1.9e-52 177.3 0.1 9.2e-52 175.1 0.1 2.0 2 0 0 2 2 2 1 Probable N6-adenine methyltransferase NmrA PF05368.13 KFY03426.1 - 6.1e-17 62.0 0.0 1e-16 61.3 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family Epimerase PF01370.21 KFY03426.1 - 6.5e-15 55.3 0.1 1.2e-14 54.4 0.1 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 KFY03426.1 - 1.3e-13 51.2 0.0 2.5e-13 50.3 0.0 1.5 1 0 0 1 1 1 1 NAD(P)H-binding 3Beta_HSD PF01073.19 KFY03426.1 - 1.7e-10 40.3 0.0 3.7e-10 39.3 0.0 1.6 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 KFY03426.1 - 4.3e-08 32.9 0.1 1.3e-07 31.3 0.0 1.7 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 KFY03426.1 - 3.4e-07 29.6 0.0 5.1e-06 25.8 0.0 2.5 1 1 0 1 1 1 1 RmlD substrate binding domain adh_short PF00106.25 KFY03426.1 - 0.00028 20.4 0.0 0.00048 19.6 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase NAD_binding_4 PF07993.12 KFY03426.1 - 0.00047 19.4 0.4 0.035 13.3 0.4 2.8 1 1 0 1 1 1 1 Male sterility protein adh_short_C2 PF13561.6 KFY03426.1 - 0.0084 15.7 0.0 0.014 15.0 0.0 1.4 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase RXLR PF16810.5 KFY03426.1 - 0.02 15.3 0.0 0.043 14.2 0.0 1.5 1 0 0 1 1 1 0 RXLR phytopathogen effector protein, Avirulence activity Polysacc_synt_2 PF02719.15 KFY03426.1 - 0.031 13.4 0.0 0.051 12.7 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein KR PF08659.10 KFY03426.1 - 0.071 13.0 0.0 5.2 6.9 0.0 2.8 3 0 0 3 3 3 0 KR domain UCH PF00443.29 KFY03427.1 - 1.7e-48 165.4 3.3 2.3e-48 165.0 3.3 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KFY03427.1 - 5.2e-26 92.0 9.8 5.2e-26 92.0 9.8 1.5 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.19 KFY03427.1 - 0.0011 19.2 0.1 0.0011 19.2 0.1 2.7 2 1 0 2 2 2 1 Zn-finger in ubiquitin-hydrolases and other protein zf_C2H2_ZHX PF18387.1 KFY03427.1 - 0.31 10.7 4.0 0.84 9.3 0.0 3.0 3 0 0 3 3 3 0 Zinc-fingers and homeoboxes C2H2 finger domain BLACT_WH PF17778.1 KFY03428.1 - 5.7e-17 61.4 0.3 1.1e-16 60.5 0.3 1.5 1 0 0 1 1 1 1 Beta-lactamase associated winged helix domain Lactamase_B PF00753.27 KFY03428.1 - 2.7e-12 47.1 4.1 2.7e-10 40.6 3.5 2.5 2 1 0 2 2 2 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 KFY03428.1 - 2.6e-05 23.8 0.1 4.2e-05 23.1 0.1 1.5 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 KFY03428.1 - 0.041 13.8 0.1 0.073 13.0 0.1 1.5 1 0 0 1 1 1 0 Beta-lactamase superfamily domain I-set PF07679.16 KFY03429.1 - 0.00015 21.8 0.1 2.9 8.0 0.1 4.7 4 0 0 4 4 4 2 Immunoglobulin I-set domain DUF1918 PF08940.11 KFY03429.1 - 0.07 12.8 0.8 6.1 6.5 0.0 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF1918) MAP70 PF07058.11 KFY03429.1 - 0.11 11.2 0.2 0.17 10.6 0.2 1.2 1 0 0 1 1 1 0 Microtubule-associated protein 70 DUF4265 PF14085.6 KFY03429.1 - 0.12 12.4 0.0 0.77 9.8 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4265) Peptidase_C12 PF01088.21 KFY03430.1 - 1.1e-60 204.9 0.0 1.5e-59 201.3 0.0 2.1 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase, family 1 UCH_C PF18031.1 KFY03430.1 - 0.0015 18.4 0.0 0.0035 17.2 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolases YccV-like PF08755.11 KFY03431.1 - 1.7e-28 99.0 0.2 3.5e-28 98.0 0.2 1.6 1 0 0 1 1 1 1 Hemimethylated DNA-binding protein YccV like Transglut_core2 PF13369.6 KFY03431.1 - 3e-17 62.6 0.0 5.9e-17 61.6 0.0 1.4 1 0 0 1 1 1 1 Transglutaminase-like superfamily F-box-like PF12937.7 KFY03431.1 - 1e-08 34.9 0.5 3.2e-08 33.3 0.5 2.0 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KFY03431.1 - 0.0002 21.2 0.0 0.00056 19.7 0.0 1.9 1 0 0 1 1 1 1 F-box domain Elongin_A PF06881.11 KFY03431.1 - 0.0099 16.4 0.1 0.026 15.1 0.1 1.7 1 0 0 1 1 1 1 RNA polymerase II transcription factor SIII (Elongin) subunit A F-box_5 PF18511.1 KFY03431.1 - 0.11 12.1 0.0 0.31 10.6 0.0 1.7 1 0 0 1 1 1 0 F-box SPX PF03105.19 KFY03432.1 - 2.3e-54 185.8 0.6 3.9e-54 185.0 0.6 1.4 1 1 0 1 1 1 1 SPX domain zf-C3HC4_3 PF13920.6 KFY03432.1 - 8.6e-08 31.9 8.3 1.5e-07 31.2 8.3 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KFY03432.1 - 1.6e-06 27.8 12.7 3.3e-06 26.9 12.7 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KFY03432.1 - 2.1e-06 27.5 11.6 4.1e-06 26.5 11.6 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 KFY03432.1 - 4.6e-06 26.7 11.4 1e-05 25.6 11.4 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.6 KFY03432.1 - 9.6e-06 25.8 10.9 1.7e-05 25.1 10.9 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 KFY03432.1 - 4e-05 23.5 9.9 7.9e-05 22.5 9.9 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 KFY03432.1 - 0.00096 19.1 8.4 0.0022 18.0 8.4 1.6 1 0 0 1 1 1 1 RING-type zinc-finger Prok-RING_4 PF14447.6 KFY03432.1 - 0.01 15.7 9.0 0.024 14.5 9.0 1.6 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_4 PF14570.6 KFY03432.1 - 0.018 14.9 3.9 0.018 14.9 3.9 1.8 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-rbx1 PF12678.7 KFY03432.1 - 0.031 14.5 6.2 0.076 13.3 6.2 1.6 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 KFY03432.1 - 0.13 12.4 2.6 0.23 11.5 2.6 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger DUF1644 PF07800.12 KFY03432.1 - 0.39 10.8 3.5 4.8 7.2 3.5 2.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1644) zf-Nse PF11789.8 KFY03432.1 - 1.7 8.5 7.4 3.5 7.5 7.4 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-RING_6 PF14835.6 KFY03432.1 - 1.9 8.4 6.0 3.6 7.5 5.2 1.8 1 1 1 2 2 2 0 zf-RING of BARD1-type protein zf-P11 PF03854.14 KFY03432.1 - 7.8 6.2 8.8 1.2e+02 2.5 9.1 2.2 1 1 1 2 2 2 0 P-11 zinc finger DnaJ PF00226.31 KFY03433.1 - 6.8e-24 83.8 0.4 1.9e-23 82.4 0.4 1.8 1 0 0 1 1 1 1 DnaJ domain zf-C2H2_jaz PF12171.8 KFY03433.1 - 4.8e-09 36.3 4.3 4.8e-09 36.3 4.3 2.4 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 KFY03433.1 - 1e-07 32.2 4.4 0.0019 18.5 1.2 2.4 2 0 0 2 2 2 2 C2H2 type zinc-finger (2 copies) zf-met PF12874.7 KFY03433.1 - 6.9e-07 29.5 2.9 6.9e-07 29.5 2.9 2.8 3 0 0 3 3 3 1 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.6 KFY03433.1 - 0.0015 19.2 2.4 2.1 9.4 0.3 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.26 KFY03433.1 - 0.0018 18.7 5.5 0.19 12.2 0.6 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type RPT PF13446.6 KFY03433.1 - 0.01 15.7 0.1 0.043 13.7 0.0 2.1 2 0 0 2 2 2 0 A repeated domain in UCH-protein DUF678 PF05077.12 KFY03433.1 - 0.49 10.6 4.8 0.15 12.2 0.9 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF678) HNH_5 PF14279.6 KFY03433.1 - 0.61 10.0 3.8 4.3 7.3 0.6 2.5 2 0 0 2 2 2 0 HNH endonuclease PSCyt3 PF07627.11 KFY03433.1 - 0.79 10.0 4.3 1.4 9.3 0.3 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1588) Peptidase_C54 PF03416.19 KFY03434.1 - 5.8e-93 311.3 0.0 7e-93 311.0 0.0 1.1 1 0 0 1 1 1 1 Peptidase family C54 R3H PF01424.22 KFY03435.1 - 1.5e-11 44.1 0.0 3.6e-11 42.9 0.0 1.7 1 0 0 1 1 1 1 R3H domain G-patch PF01585.23 KFY03435.1 - 6.3e-10 38.8 0.9 6.3e-10 38.8 0.9 2.1 2 0 0 2 2 2 1 G-patch domain Chromo PF00385.24 KFY03435.1 - 0.00054 19.8 0.0 0.0011 18.8 0.0 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain G-patch_2 PF12656.7 KFY03435.1 - 0.00086 19.3 2.0 0.0025 17.8 0.3 2.6 2 0 0 2 2 2 1 G-patch domain Histone PF00125.24 KFY03436.1 - 1.2e-22 80.7 2.0 1.5e-22 80.4 2.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 KFY03436.1 - 4.1e-05 23.8 0.0 0.0001 22.5 0.0 1.6 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.13 KFY03436.1 - 0.00025 21.5 0.0 0.00043 20.7 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A RP-C PF03428.13 KFY03436.1 - 0.025 14.2 0.1 0.057 13.1 0.1 1.6 1 1 0 1 1 1 0 Replication protein C N-terminal domain Histone_H2A_C PF16211.5 KFY03437.1 - 1.1e-20 73.1 3.1 1.9e-20 72.3 3.1 1.4 1 0 0 1 1 1 1 C-terminus of histone H2A Histone PF00125.24 KFY03437.1 - 1.1e-16 61.4 0.0 1.4e-16 61.0 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 KFY03437.1 - 9.7e-06 25.8 0.0 1.3e-05 25.3 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Complex1_LYR PF05347.15 KFY03438.1 - 1.3e-08 34.7 1.6 1.9e-08 34.2 1.6 1.3 1 0 0 1 1 1 1 Complex 1 protein (LYR family) 2-oxoacid_dh PF00198.23 KFY03439.1 - 5.3e-78 261.7 0.0 7.9e-78 261.1 0.0 1.3 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 KFY03439.1 - 4.6e-16 58.4 1.1 8.3e-16 57.6 1.1 1.4 1 0 0 1 1 1 1 Biotin-requiring enzyme SAGA-Tad1 PF12767.7 KFY03439.1 - 0.08 12.7 3.6 0.13 12.0 3.6 1.4 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit FAM76 PF16046.5 KFY03439.1 - 0.29 10.4 5.5 3.8 6.8 3.9 2.0 2 0 0 2 2 2 0 FAM76 protein Presenilin PF01080.17 KFY03439.1 - 0.48 9.1 5.7 0.67 8.7 5.7 1.1 1 0 0 1 1 1 0 Presenilin Ndc1_Nup PF09531.10 KFY03439.1 - 1.5 7.4 7.9 2 7.0 7.9 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Apt1 PF10351.9 KFY03439.1 - 3.3 6.5 7.5 4.6 6.0 7.5 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain CDC45 PF02724.14 KFY03439.1 - 5 5.3 5.8 6.5 4.9 5.8 1.1 1 0 0 1 1 1 0 CDC45-like protein Ytp1 PF10355.9 KFY03440.1 - 5.1e-115 383.5 7.8 1.3e-114 382.2 7.8 1.6 1 0 0 1 1 1 1 Protein of unknown function (Ytp1) DUF2427 PF10348.9 KFY03440.1 - 6.7e-29 99.8 13.6 2.3e-28 98.0 5.4 2.6 2 0 0 2 2 2 2 Domain of unknown function (DUF2427) K_oxygenase PF13434.6 KFY03440.1 - 4e-18 65.7 0.0 2.1e-13 50.1 0.0 2.2 2 0 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.6 KFY03440.1 - 1.7e-07 30.8 0.0 0.0046 16.3 0.0 2.5 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KFY03440.1 - 6.7e-06 25.5 0.0 0.035 13.3 0.0 2.8 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KFY03440.1 - 0.00064 19.7 0.0 1.3 9.0 0.0 2.8 2 0 0 2 2 2 2 FAD-NAD(P)-binding GIDA PF01134.22 KFY03440.1 - 0.017 14.2 0.0 0.37 9.8 0.0 2.6 2 0 0 2 2 2 0 Glucose inhibited division protein A Lycopene_cycl PF05834.12 KFY03440.1 - 0.071 12.1 0.0 0.14 11.2 0.0 1.4 1 0 0 1 1 1 0 Lycopene cyclase protein Shikimate_DH PF01488.20 KFY03440.1 - 0.14 12.2 0.2 1.1 9.4 0.0 2.4 3 0 0 3 3 3 0 Shikimate / quinate 5-dehydrogenase KNOX1 PF03790.13 KFY03440.1 - 0.46 10.2 1.4 11 5.9 0.3 2.6 2 0 0 2 2 2 0 KNOX1 domain NAD_binding_8 PF13450.6 KFY03440.1 - 1.5 9.1 3.3 2 8.7 0.0 2.9 3 0 0 3 3 3 0 NAD(P)-binding Rossmann-like domain SprT-like PF10263.9 KFY03443.1 - 1.7e-39 134.1 0.1 2.8e-39 133.5 0.1 1.3 1 0 0 1 1 1 1 SprT-like family Glyco_hydro_72 PF03198.14 KFY03444.1 - 3e-138 460.4 3.3 4e-111 371.3 1.9 2.2 1 1 1 2 2 2 2 Glucanosyltransferase X8 PF07983.13 KFY03444.1 - 6.3e-26 90.9 7.3 6.3e-26 90.9 7.3 2.0 2 0 0 2 2 2 1 X8 domain Glucan_synthase PF02364.15 KFY03445.1 - 0 1381.6 0.0 0 1380.9 0.0 1.3 1 0 0 1 1 1 1 1,3-beta-glucan synthase component FKS1_dom1 PF14288.6 KFY03445.1 - 2.1e-43 147.7 1.2 6.7e-43 146.1 1.2 1.9 1 1 0 1 1 1 1 1,3-beta-glucan synthase subunit FKS1, domain-1 XhlA PF10779.9 KFY03445.1 - 0.24 11.6 1.0 0.79 10.0 1.0 1.9 1 0 0 1 1 1 0 Haemolysin XhlA GWT1 PF06423.12 KFY03450.1 - 9.8e-41 139.3 2.4 2.4e-40 138.1 2.3 1.8 2 0 0 2 2 2 1 GWT1 DUF4896 PF16237.5 KFY03450.1 - 0.053 13.4 1.9 0.59 10.0 0.2 3.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4896) DUF4818 PF16089.5 KFY03450.1 - 0.11 12.9 2.0 0.23 11.9 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4818) DUF1129 PF06570.11 KFY03450.1 - 0.3 10.6 1.8 0.98 8.9 0.3 2.4 2 1 1 3 3 3 0 Protein of unknown function (DUF1129) FAD-oxidase_C PF02913.19 KFY03453.1 - 5.5e-60 203.1 0.2 5.5e-60 203.1 0.2 2.4 2 0 0 2 2 2 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 KFY03453.1 - 6.7e-36 123.1 0.0 1.5e-35 122.0 0.0 1.6 1 0 0 1 1 1 1 FAD binding domain Clr5 PF14420.6 KFY03453.1 - 1.2e-20 73.4 4.5 1.2e-20 73.4 4.5 2.6 3 0 0 3 3 3 1 Clr5 domain WD40 PF00400.32 KFY03453.1 - 0.012 16.5 0.1 9.2 7.3 0.0 3.0 2 0 0 2 2 2 0 WD domain, G-beta repeat MCM6_C PF18263.1 KFY03453.1 - 0.062 13.5 0.1 0.24 11.7 0.1 2.1 1 0 0 1 1 1 0 MCM6 C-terminal winged-helix domain HEXIM PF15313.6 KFY03453.1 - 0.43 10.8 4.9 2.5 8.3 4.9 2.4 1 0 0 1 1 1 0 Hexamethylene bis-acetamide-inducible protein DUF4230 PF14014.6 KFY03453.1 - 1.6 9.0 5.1 22 5.3 2.7 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF4230) FMN_dh PF01070.18 KFY03454.1 - 2.2e-107 359.1 0.0 2.7e-107 358.8 0.0 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.28 KFY03454.1 - 6.2e-13 48.7 0.0 1.5e-12 47.4 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Glu_synthase PF01645.17 KFY03454.1 - 2.3e-07 30.3 0.2 4.4e-07 29.4 0.2 1.4 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.25 KFY03454.1 - 2.2e-05 23.6 0.3 0.00011 21.4 0.2 2.1 2 1 1 3 3 3 1 IMP dehydrogenase / GMP reductase domain NMO PF03060.15 KFY03454.1 - 0.016 14.6 0.2 0.026 13.9 0.2 1.3 1 0 0 1 1 1 0 Nitronate monooxygenase BPL_C PF02237.17 KFY03454.1 - 0.018 14.9 0.0 0.047 13.6 0.0 1.6 1 0 0 1 1 1 0 Biotin protein ligase C terminal domain ThiG PF05690.14 KFY03454.1 - 0.023 14.0 0.0 6.8 5.9 0.0 2.3 1 1 1 2 2 2 0 Thiazole biosynthesis protein ThiG His_biosynth PF00977.21 KFY03454.1 - 0.031 13.7 0.0 0.058 12.9 0.0 1.3 1 0 0 1 1 1 0 Histidine biosynthesis protein Ribul_P_3_epim PF00834.19 KFY03454.1 - 0.042 13.2 0.0 0.071 12.5 0.0 1.3 1 0 0 1 1 1 0 Ribulose-phosphate 3 epimerase family DHO_dh PF01180.21 KFY03454.1 - 0.13 11.5 0.0 0.2 10.8 0.0 1.3 1 1 0 1 1 1 0 Dihydroorotate dehydrogenase adh_short_C2 PF13561.6 KFY03455.1 - 1.1e-35 123.4 3.4 1.6e-35 122.8 3.4 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KFY03455.1 - 5.1e-30 104.4 2.7 7.2e-30 103.9 2.7 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KFY03455.1 - 2e-07 31.1 3.6 2.5e-06 27.5 3.6 2.0 1 1 0 1 1 1 1 KR domain Shikimate_DH PF01488.20 KFY03455.1 - 0.16 12.0 0.4 0.36 10.9 0.4 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase DUF1772 PF08592.11 KFY03456.1 - 1.3e-08 35.2 0.1 2.3e-08 34.5 0.1 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF1772) YusW PF14039.6 KFY03456.1 - 0.15 12.6 0.0 0.22 12.1 0.0 1.2 1 0 0 1 1 1 0 YusW-like protein DUF1932 PF09130.11 KFY03457.1 - 3.1e-22 78.3 0.1 8.1e-22 77.0 0.1 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1932) F420_oxidored PF03807.17 KFY03457.1 - 5.1e-06 27.0 0.0 1.1e-05 25.9 0.0 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.15 KFY03457.1 - 4.1e-05 23.8 0.0 6e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase 2-Hacid_dh_C PF02826.19 KFY03457.1 - 0.0012 18.3 0.0 0.0019 17.6 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Rossmann-like PF10727.9 KFY03457.1 - 0.0065 16.3 0.1 0.012 15.5 0.1 1.3 1 0 0 1 1 1 1 Rossmann-like domain 3HCDH_N PF02737.18 KFY03457.1 - 0.067 13.1 0.0 0.11 12.4 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Shikimate_DH PF01488.20 KFY03457.1 - 0.12 12.4 0.0 0.22 11.6 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase PDH PF02153.17 KFY03457.1 - 0.16 10.9 0.0 0.25 10.3 0.0 1.3 1 0 0 1 1 1 0 Prephenate dehydrogenase INCA1 PF15142.6 KFY03458.1 - 0.018 15.1 0.1 0.053 13.5 0.0 1.8 2 0 0 2 2 2 0 INCA1 zf-RanBP PF00641.18 KFY03458.1 - 0.31 10.4 3.2 0.6 9.5 3.2 1.5 1 0 0 1 1 1 0 Zn-finger in Ran binding protein and others IBR PF01485.21 KFY03458.1 - 0.38 11.0 5.0 0.98 9.7 5.0 1.6 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain RRM_1 PF00076.22 KFY03459.1 - 4.5e-17 61.6 0.0 6.9e-17 61.0 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FoP_duplication PF13865.6 KFY03459.1 - 4.7e-08 33.5 13.1 4.7e-08 33.5 13.1 3.4 3 0 0 3 3 3 1 C-terminal duplication domain of Friend of PRMT1 Nup35_RRM_2 PF14605.6 KFY03465.1 - 0.00041 20.3 0.0 0.0044 17.0 0.1 2.2 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif RRM_1 PF00076.22 KFY03465.1 - 0.00067 19.4 5.0 0.00096 18.9 0.2 2.9 3 0 0 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KFY03465.1 - 0.023 14.6 0.0 0.055 13.3 0.0 1.6 1 0 0 1 1 1 0 Occluded RNA-recognition motif PHM7_cyt PF14703.6 KFY03465.1 - 0.074 13.3 1.4 0.84 9.9 0.0 2.4 2 0 0 2 2 2 0 Cytosolic domain of 10TM putative phosphate transporter RRM_3 PF08777.11 KFY03465.1 - 0.17 11.9 7.2 0.18 11.8 0.1 3.1 3 0 0 3 3 3 0 RNA binding motif CLZ PF16526.5 KFY03465.1 - 2.1 8.8 12.6 0.69 10.3 9.0 2.0 2 0 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels DUF2937 PF11157.8 KFY03465.1 - 2.8 7.6 6.4 0.34 10.6 1.7 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2937) SWIRM-assoc_1 PF16495.5 KFY03466.1 - 1.2e-31 108.4 8.5 2.4e-31 107.5 8.5 1.5 1 0 0 1 1 1 1 SWIRM-associated region 1 SWIRM PF04433.17 KFY03466.1 - 2.8e-31 107.7 0.2 6.7e-31 106.5 0.2 1.7 1 0 0 1 1 1 1 SWIRM domain Myb_DNA-binding PF00249.31 KFY03466.1 - 7.5e-10 38.9 0.1 1.5e-09 37.8 0.1 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 KFY03466.1 - 2.9e-05 24.2 0.1 7.1e-05 23.0 0.1 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain Mei5 PF10376.9 KFY03466.1 - 0.052 13.4 0.6 0.12 12.3 0.6 1.5 1 0 0 1 1 1 0 Double-strand recombination repair protein ETF PF01012.21 KFY03467.1 - 4.7e-44 150.5 3.1 7.9e-44 149.7 3.1 1.3 1 0 0 1 1 1 1 Electron transfer flavoprotein domain ETF_alpha PF00766.19 KFY03467.1 - 4.3e-33 113.2 0.4 1.1e-32 111.9 0.4 1.7 1 0 0 1 1 1 1 Electron transfer flavoprotein FAD-binding domain Pyr_redox_2 PF07992.14 KFY03468.1 - 1.1e-08 34.7 0.0 4.5e-06 26.1 0.0 3.0 2 2 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase PEGSRP PF07623.11 KFY03469.1 - 0.12 12.1 0.7 0.41 10.5 0.7 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF1584) MutL_C PF08676.11 KFY03470.1 - 2.9e-24 85.5 0.0 6.7e-24 84.3 0.0 1.6 1 0 0 1 1 1 1 MutL C terminal dimerisation domain DNA_mis_repair PF01119.19 KFY03470.1 - 1.2e-18 66.9 0.0 3.7e-18 65.3 0.0 1.9 2 0 0 2 2 2 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.6 KFY03470.1 - 3.7e-13 49.5 0.7 1.3e-11 44.5 0.1 3.1 3 0 0 3 3 3 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 KFY03470.1 - 5.9e-07 30.0 0.5 1.6e-06 28.6 0.0 2.0 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase ATP_synt_H PF05493.13 KFY03471.1 - 4e-24 84.9 1.9 4.5e-24 84.7 1.9 1.0 1 0 0 1 1 1 1 ATP synthase subunit H DUF1129 PF06570.11 KFY03471.1 - 0.075 12.5 0.5 0.092 12.2 0.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1129) Pox_A14 PF05767.12 KFY03471.1 - 0.12 12.5 1.2 0.15 12.2 1.2 1.1 1 0 0 1 1 1 0 Poxvirus virion envelope protein A14 Arv1 PF04161.13 KFY03472.1 - 1.8e-37 129.6 0.1 2.1e-37 129.4 0.1 1.0 1 0 0 1 1 1 1 Arv1-like family DUF3419 PF11899.8 KFY03484.1 - 4.7e-84 282.8 0.0 5.3e-84 282.6 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3419) Cutinase PF01083.22 KFY03485.1 - 5.5e-55 186.1 7.3 6.6e-55 185.8 7.3 1.1 1 0 0 1 1 1 1 Cutinase PE-PPE PF08237.11 KFY03485.1 - 6e-05 22.7 0.2 9.6e-05 22.0 0.2 1.3 1 0 0 1 1 1 1 PE-PPE domain CBM_1 PF00734.18 KFY03485.1 - 0.035 14.1 13.1 0.035 14.1 13.1 3.8 3 1 0 3 3 3 0 Fungal cellulose binding domain Hydrolase_4 PF12146.8 KFY03485.1 - 0.044 13.0 0.0 0.072 12.3 0.0 1.2 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Acyl-CoA_dh_1 PF00441.24 KFY03486.1 - 1.1e-29 103.6 0.9 1.5e-29 103.1 0.9 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 KFY03486.1 - 3.2e-23 82.5 0.0 8.1e-23 81.2 0.0 1.7 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 KFY03486.1 - 7.6e-23 80.5 0.1 1.3e-22 79.8 0.1 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 KFY03486.1 - 6.4e-05 23.2 0.0 0.0001 22.6 0.0 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain CFEM PF05730.11 KFY03487.1 - 8.8e-10 38.5 13.9 1.4e-09 37.9 13.9 1.3 1 0 0 1 1 1 1 CFEM domain Pex14_N PF04695.13 KFY03487.1 - 0.041 14.5 3.3 0.057 14.1 3.3 1.3 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Atg29_N PF18388.1 KFY03488.1 - 1.7e-25 88.6 1.7 3e-25 87.8 1.7 1.4 1 0 0 1 1 1 1 Atg29 N-terminal domain NUDIX PF00293.28 KFY03488.1 - 5.3e-10 39.5 0.0 9.2e-10 38.7 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain Acetyltransf_1 PF00583.25 KFY03489.1 - 7.3e-07 29.4 0.0 9.9e-07 29.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KFY03489.1 - 0.00016 22.0 0.0 0.00024 21.4 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KFY03489.1 - 0.00045 20.1 0.0 0.0009 19.2 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Gpr1_Fun34_YaaH PF01184.19 KFY03490.1 - 1.1e-33 116.7 18.5 1.3e-33 116.4 18.5 1.1 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family DUF4229 PF14012.6 KFY03490.1 - 0.011 15.9 4.0 0.011 15.9 4.0 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF4229) DUF1129 PF06570.11 KFY03490.1 - 0.045 13.3 2.4 0.074 12.5 2.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1129) DAD PF02109.16 KFY03490.1 - 0.27 11.5 9.4 0.11 12.9 6.8 1.6 1 1 0 1 1 1 0 DAD family Septin PF00735.18 KFY03491.1 - 1.9e-32 112.7 0.0 1.1e-10 41.2 0.0 3.1 3 0 0 3 3 3 3 Septin FtsK_SpoIIIE PF01580.18 KFY03491.1 - 0.0026 17.2 0.0 0.0044 16.4 0.0 1.3 1 0 0 1 1 1 1 FtsK/SpoIIIE family G-alpha PF00503.20 KFY03491.1 - 0.0035 16.6 0.1 0.041 13.1 0.0 2.4 3 0 0 3 3 3 1 G-protein alpha subunit Dynamin_N PF00350.23 KFY03491.1 - 0.042 13.9 0.6 1.3 9.1 0.0 2.4 2 0 0 2 2 2 0 Dynamin family Prefoldin PF02996.17 KFY03493.1 - 0.00056 19.8 12.5 0.0011 18.8 2.1 3.6 2 1 1 3 3 3 1 Prefoldin subunit Fez1 PF06818.15 KFY03493.1 - 0.0034 17.9 9.0 0.0034 17.9 9.0 1.9 2 0 0 2 2 2 1 Fez1 HrpB7 PF09486.10 KFY03493.1 - 0.022 15.2 13.4 0.079 13.4 12.0 2.4 2 1 0 2 2 2 0 Bacterial type III secretion protein (HrpB7) BLOC1_2 PF10046.9 KFY03493.1 - 0.027 14.7 4.4 0.027 14.7 4.4 2.6 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 HlyD_2 PF12700.7 KFY03493.1 - 0.046 12.5 0.7 0.068 11.9 0.7 1.3 1 0 0 1 1 1 0 HlyD family secretion protein DUF3138 PF11336.8 KFY03493.1 - 0.13 10.9 0.5 0.18 10.4 0.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) MPS2 PF17060.5 KFY03493.1 - 0.13 11.5 5.4 0.22 10.8 5.4 1.5 1 1 0 1 1 1 0 Monopolar spindle protein 2 DUF1664 PF07889.12 KFY03493.1 - 0.28 11.2 5.5 1.5 8.9 1.9 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) HR1 PF02185.16 KFY03493.1 - 0.31 11.2 14.3 0.068 13.3 1.8 3.3 2 1 0 3 3 3 0 Hr1 repeat Baculo_PEP_C PF04513.12 KFY03493.1 - 0.35 10.9 3.5 0.86 9.6 0.9 2.4 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF948 PF06103.11 KFY03493.1 - 0.5 10.6 1.9 2 8.7 0.5 2.5 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) Exonuc_VII_L PF02601.15 KFY03493.1 - 0.86 9.1 9.1 1.2 8.6 8.5 1.6 1 1 0 1 1 1 0 Exonuclease VII, large subunit TPR_MLP1_2 PF07926.12 KFY03493.1 - 0.88 9.6 18.2 1.3 9.1 6.9 3.5 3 0 0 3 3 3 0 TPR/MLP1/MLP2-like protein NPV_P10 PF05531.12 KFY03493.1 - 1.2 9.7 4.9 1.9 9.0 0.6 3.1 2 1 1 3 3 2 0 Nucleopolyhedrovirus P10 protein MerR-DNA-bind PF09278.11 KFY03493.1 - 1.4 9.5 14.9 13 6.4 2.7 3.4 2 1 0 2 2 2 0 MerR, DNA binding Spc7 PF08317.11 KFY03493.1 - 1.5 7.7 19.0 0.2 10.5 7.1 2.3 1 1 1 2 2 2 0 Spc7 kinetochore protein DUF16 PF01519.16 KFY03493.1 - 1.6 9.3 6.9 12 6.4 6.9 2.5 1 1 0 1 1 1 0 Protein of unknown function DUF16 DUF3552 PF12072.8 KFY03493.1 - 1.7 8.0 17.0 0.077 12.4 4.7 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3552) Jnk-SapK_ap_N PF09744.9 KFY03493.1 - 2 8.6 20.7 0.19 11.9 4.6 2.9 3 0 0 3 3 3 0 JNK_SAPK-associated protein-1 ABC_tran_CTD PF16326.5 KFY03493.1 - 4.2 7.7 23.4 8.4 6.7 10.8 3.9 1 1 2 3 3 3 0 ABC transporter C-terminal domain Laminin_II PF06009.12 KFY03493.1 - 5.4 7.0 11.0 1.8 8.6 2.8 2.7 2 2 2 4 4 3 0 Laminin Domain II SlyX PF04102.12 KFY03493.1 - 5.5 7.7 15.4 9.9 6.9 1.9 3.7 2 1 1 3 3 3 0 SlyX Wtap PF17098.5 KFY03493.1 - 5.7 6.8 13.7 1.5 8.7 8.6 2.6 1 1 0 2 2 2 0 WTAP/Mum2p family Cob_adeno_trans PF01923.18 KFY03493.1 - 5.8 7.0 8.3 3.7 7.7 4.3 2.4 1 1 2 3 3 3 0 Cobalamin adenosyltransferase OmpH PF03938.14 KFY03493.1 - 6.5 7.1 20.1 3 8.2 7.8 2.7 2 1 0 3 3 3 0 Outer membrane protein (OmpH-like) DUF641 PF04859.12 KFY03493.1 - 6.9 7.0 15.2 15 6.0 1.2 3.4 1 1 2 3 3 3 0 Plant protein of unknown function (DUF641) BST2 PF16716.5 KFY03493.1 - 7.9 7.1 13.8 4.4 8.0 5.7 2.8 2 0 0 2 2 2 0 Bone marrow stromal antigen 2 HIP1_clath_bdg PF16515.5 KFY03493.1 - 8.6 7.0 16.9 8 7.2 2.2 2.9 2 0 0 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Ribosomal_L37e PF01907.19 KFY03494.1 - 7.1e-27 93.3 10.0 1.1e-26 92.8 10.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L37e DZR PF12773.7 KFY03494.1 - 0.013 15.5 0.9 0.021 14.8 0.9 1.3 1 0 0 1 1 1 0 Double zinc ribbon HypA PF01155.19 KFY03494.1 - 0.028 14.4 0.2 0.039 14.0 0.2 1.2 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Rubredoxin_2 PF18073.1 KFY03494.1 - 0.13 12.0 2.7 1.4 8.7 0.2 2.2 2 0 0 2 2 2 0 Rubredoxin metal binding domain zinc_ribbon_2 PF13240.6 KFY03494.1 - 0.76 9.6 3.5 18 5.2 3.9 2.4 1 1 1 2 2 2 0 zinc-ribbon domain zf-C3HC4_2 PF13923.6 KFY03494.1 - 1.5 8.7 5.3 2.6 8.0 5.3 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) CENP-O PF09496.10 KFY03495.1 - 1.2e-64 218.2 0.0 3.8e-64 216.6 0.0 1.8 2 0 0 2 2 2 1 Cenp-O kinetochore centromere component ELP6 PF09807.9 KFY03495.1 - 6.4e-18 65.1 0.0 1.1e-17 64.3 0.0 1.3 1 0 0 1 1 1 1 Elongation complex protein 6 ATPase PF06745.13 KFY03495.1 - 0.029 13.7 0.0 0.059 12.7 0.0 1.4 1 0 0 1 1 1 0 KaiC AAA_16 PF13191.6 KFY03495.1 - 0.093 13.1 0.1 0.25 11.7 0.1 1.7 1 0 0 1 1 1 0 AAA ATPase domain ABC_tran_CTD PF16326.5 KFY03495.1 - 0.2 12.0 0.6 0.38 11.0 0.6 1.5 1 0 0 1 1 1 0 ABC transporter C-terminal domain RRM_1 PF00076.22 KFY03496.1 - 1.4e-81 268.3 3.9 4.6e-22 77.6 0.2 5.4 5 0 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PABP PF00658.18 KFY03496.1 - 1.4e-26 92.4 0.4 1.4e-26 92.4 0.4 2.9 3 0 0 3 3 3 1 Poly-adenylate binding protein, unique domain RRM_5 PF13893.6 KFY03496.1 - 8.2e-10 38.3 0.0 0.044 13.4 0.0 5.2 3 2 2 5 5 5 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 KFY03496.1 - 3.8e-06 26.9 0.5 1.3 9.2 0.0 5.3 5 0 0 5 5 5 1 RNA recognition motif CbiG_mid PF11761.8 KFY03496.1 - 0.00025 21.1 3.4 3 8.0 0.0 4.1 4 0 0 4 4 3 2 Cobalamin biosynthesis central region RRM_occluded PF16842.5 KFY03496.1 - 0.00031 20.5 0.1 0.3 11.0 0.0 3.4 4 0 0 4 4 3 1 Occluded RNA-recognition motif Limkain-b1 PF11608.8 KFY03496.1 - 0.0027 17.7 1.3 9.8 6.3 0.1 3.7 3 1 0 3 3 3 0 Limkain b1 OB_RNB PF08206.11 KFY03496.1 - 0.014 15.0 1.1 7.8 6.3 0.0 3.6 3 0 0 3 3 3 0 Ribonuclease B OB domain Nup35_RRM_2 PF14605.6 KFY03496.1 - 0.031 14.3 0.9 40 4.3 0.0 3.9 4 0 0 4 4 4 0 Nup53/35/40-type RNA recognition motif SET_assoc PF11767.8 KFY03496.1 - 0.033 13.8 0.1 1.1 8.9 0.0 2.8 3 0 0 3 3 3 0 Histone lysine methyltransferase SET associated Caldesmon PF02029.15 KFY03496.1 - 0.043 12.6 26.0 0.068 11.9 26.0 1.2 1 0 0 1 1 1 0 Caldesmon Nefa_Nip30_N PF10187.9 KFY03496.1 - 0.044 14.1 0.3 0.044 14.1 0.3 3.4 3 0 0 3 3 2 0 N-terminal domain of NEFA-interacting nuclear protein NIP30 SAPS PF04499.15 KFY03496.1 - 0.092 11.5 6.4 0.15 10.8 6.4 1.4 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein NPR3 PF03666.13 KFY03496.1 - 0.66 8.7 8.9 1 8.1 8.9 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Eapp_C PF10238.9 KFY03496.1 - 1.4 9.0 7.2 4.7 7.3 7.2 2.0 1 0 0 1 1 1 0 E2F-associated phosphoprotein DUF2151 PF10221.9 KFY03496.1 - 1.6 7.2 11.1 2.4 6.6 11.1 1.2 1 0 0 1 1 1 0 Cell cycle and development regulator CDC45 PF02724.14 KFY03496.1 - 2.3 6.4 18.1 3.3 5.9 18.1 1.2 1 0 0 1 1 1 0 CDC45-like protein DUF913 PF06025.12 KFY03496.1 - 3.1 6.7 8.3 5.4 5.9 8.3 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Presenilin PF01080.17 KFY03496.1 - 3.3 6.4 10.5 4.9 5.8 10.5 1.2 1 0 0 1 1 1 0 Presenilin TP53IP5 PF15331.6 KFY03496.1 - 4 7.5 9.6 8.3 6.5 9.6 1.5 1 0 0 1 1 1 0 Cellular tumour antigen p53-inducible 5 Zip PF02535.22 KFY03496.1 - 4 6.6 5.3 6.3 5.9 5.3 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Neur_chan_memb PF02932.16 KFY03496.1 - 4.4 7.3 4.2 8 6.4 4.2 1.5 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DNA_pol_phi PF04931.13 KFY03496.1 - 5.7 4.9 18.3 8.2 4.4 18.3 1.2 1 0 0 1 1 1 0 DNA polymerase phi SLC12 PF03522.15 KFY03496.1 - 6 5.8 9.6 10 5.0 9.6 1.4 1 0 0 1 1 1 0 Solute carrier family 12 DUF4820 PF16091.5 KFY03496.1 - 6.3 6.1 11.7 13 5.1 11.7 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) HECT PF00632.25 KFY03497.1 - 5.7e-82 275.6 0.0 9.4e-82 274.9 0.0 1.3 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) IQ PF00612.27 KFY03497.1 - 0.0065 16.2 0.1 0.022 14.5 0.1 1.9 1 0 0 1 1 1 1 IQ calmodulin-binding motif MRP-L27 PF09809.9 KFY03498.1 - 2.7e-19 69.1 0.4 3.5e-19 68.7 0.4 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L27 Utp14 PF04615.13 KFY03499.1 - 5.4e-210 699.8 60.0 5.4e-210 699.8 60.0 2.1 1 1 1 2 2 2 1 Utp14 protein Peptidase_C2 PF00648.21 KFY03500.1 - 3.9e-60 203.4 1.7 6.6e-30 104.1 0.0 3.1 3 0 0 3 3 3 3 Calpain family cysteine protease Bgal_small_N PF02929.17 KFY03520.1 - 7.4e-41 140.4 0.1 9.3e-41 140.0 0.1 1.1 1 0 0 1 1 1 1 Beta galactosidase small chain ILVD_EDD PF00920.21 KFY03521.1 - 1.7e-209 696.7 2.4 2e-209 696.5 2.4 1.0 1 0 0 1 1 1 1 Dehydratase family Kinetochor_Ybp2 PF08568.10 KFY03522.1 - 5.3e-120 401.8 0.0 7e-120 401.4 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family, YAP/Alf4/glomulin SH3_3 PF08239.11 KFY03523.1 - 0.1 12.9 0.0 0.19 12.0 0.0 1.4 1 0 0 1 1 1 0 Bacterial SH3 domain Methyltransf_24 PF13578.6 KFY03524.1 - 0.00069 20.6 0.0 0.0014 19.6 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain MFS_5 PF05631.14 KFY03525.1 - 7e-75 252.1 12.0 9.7e-75 251.7 12.0 1.2 1 0 0 1 1 1 1 Sugar-tranasporters, 12 TM MFS_1 PF07690.16 KFY03525.1 - 7.5e-22 77.7 28.3 1.3e-20 73.6 30.6 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily MFS_1_like PF12832.7 KFY03525.1 - 8.9e-05 21.5 6.6 0.0018 17.2 0.1 2.7 2 1 0 2 2 2 2 MFS_1 like family Gaa1 PF04114.14 KFY03525.1 - 0.0042 16.2 2.8 0.0042 16.2 2.8 1.6 2 0 0 2 2 2 1 Gaa1-like, GPI transamidase component DUF63 PF01889.17 KFY03525.1 - 0.24 11.6 8.8 0.032 14.4 3.0 2.1 2 0 0 2 2 2 0 Membrane protein of unknown function DUF63 BAR PF03114.18 KFY03526.1 - 4.5e-64 216.4 3.8 5.5e-64 216.1 3.8 1.1 1 0 0 1 1 1 1 BAR domain CP12 PF02672.15 KFY03526.1 - 0.022 15.5 0.0 0.14 13.0 0.0 2.3 2 1 0 2 2 2 0 CP12 domain SVIP PF15811.5 KFY03526.1 - 0.17 12.4 0.5 0.17 12.4 0.5 2.2 3 1 0 3 3 3 0 Small VCP/p97-interacting protein BBE PF08031.12 KFY03532.1 - 0.0017 18.4 2.4 0.0021 18.1 1.0 1.9 2 0 0 2 2 2 1 Berberine and berberine like FAD_binding_4 PF01565.23 KFY03532.1 - 0.039 13.7 0.0 0.082 12.6 0.0 1.6 1 0 0 1 1 1 0 FAD binding domain NmrA PF05368.13 KFY03533.1 - 5.9e-15 55.5 0.0 3.4e-14 53.0 0.0 1.8 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KFY03533.1 - 5.2e-11 42.8 0.0 7.4e-11 42.3 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KFY03533.1 - 0.0019 17.7 0.0 0.007 15.9 0.0 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Hva1_TUDOR PF11160.8 KFY03534.1 - 7.1e-14 51.7 0.3 7.1e-14 51.7 0.3 1.5 2 0 0 2 2 2 1 Hypervirulence associated proteins TUDOR domain His_Phos_1 PF00300.22 KFY03535.1 - 1.8e-10 40.8 0.0 6.2e-10 39.1 0.0 1.8 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) RAP1 PF07218.11 KFY03535.1 - 1.2 7.3 7.8 1.9 6.6 7.8 1.2 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) FSA_C PF10479.9 KFY03535.1 - 4.4 5.3 11.5 6 4.9 11.5 1.1 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus Gelsolin PF00626.22 KFY03536.1 - 5e-36 122.5 0.0 4.8e-12 45.6 0.0 3.4 3 0 0 3 3 3 3 Gelsolin repeat Hemerythrin PF01814.23 KFY03536.1 - 0.00062 20.4 0.0 0.0015 19.2 0.0 1.6 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain MFS_1 PF07690.16 KFY03537.1 - 2e-42 145.4 67.6 2.5e-36 125.3 24.7 2.5 3 1 0 3 3 3 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KFY03537.1 - 1.5e-15 57.0 5.8 1.5e-15 57.0 5.8 3.2 2 1 1 3 3 3 2 Sugar (and other) transporter TRI12 PF06609.13 KFY03537.1 - 1.8e-15 56.4 13.9 2.5e-15 55.9 13.9 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Trypan_PARP PF05887.11 KFY03537.1 - 0.4 10.6 3.0 0.8 9.7 3.0 1.5 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) DJ-1_PfpI PF01965.24 KFY03538.1 - 7.1e-08 32.4 0.0 2.2e-07 30.8 0.0 1.8 1 1 0 1 1 1 1 DJ-1/PfpI family Mito_carr PF00153.27 KFY03539.1 - 2.5e-46 155.5 3.8 4.6e-17 61.7 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Voltage_CLC PF00654.20 KFY03540.1 - 1.6e-84 284.2 38.1 1.6e-84 284.2 38.1 1.7 2 0 0 2 2 2 1 Voltage gated chloride channel CBS PF00571.28 KFY03540.1 - 0.00041 20.7 0.0 0.011 16.2 0.1 2.4 2 0 0 2 2 2 1 CBS domain Neurochondrin PF05536.11 KFY03541.1 - 1e-71 242.1 0.2 1.4e-71 241.7 0.2 1.1 1 0 0 1 1 1 1 Neurochondrin DUF3993 PF13158.6 KFY03541.1 - 0.058 13.6 0.0 0.12 12.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3993) MARVEL PF01284.23 KFY03542.1 - 2.9e-06 27.4 2.9 2.9e-06 27.4 2.9 2.2 2 0 0 2 2 2 1 Membrane-associating domain Epimerase PF01370.21 KFY03543.1 - 6.5e-07 29.0 0.0 9.3e-07 28.5 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 KFY03543.1 - 0.00093 19.1 0.0 0.0014 18.6 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding 3Beta_HSD PF01073.19 KFY03543.1 - 0.012 14.7 0.0 0.016 14.2 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 KFY03543.1 - 0.037 13.2 0.0 0.061 12.5 0.0 1.3 1 0 0 1 1 1 0 Male sterility protein Semialdhyde_dh PF01118.24 KFY03543.1 - 0.079 13.4 0.0 0.16 12.4 0.0 1.5 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain NmrA PF05368.13 KFY03543.1 - 0.11 12.0 0.0 0.19 11.2 0.0 1.3 1 0 0 1 1 1 0 NmrA-like family CFEM PF05730.11 KFY03545.1 - 6.2e-06 26.2 4.2 8.7e-06 25.7 4.2 1.2 1 0 0 1 1 1 1 CFEM domain FAD_binding_6 PF00970.24 KFY03546.1 - 1e-27 96.4 0.0 1.8e-27 95.6 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.21 KFY03546.1 - 1.1e-26 93.6 0.0 1.6e-26 93.1 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.12 KFY03546.1 - 0.00049 20.2 0.0 0.023 14.8 0.0 2.2 2 0 0 2 2 2 1 Ferric reductase NAD binding domain Ribosomal_L12 PF00542.19 KFY03547.1 - 2.7e-18 66.1 1.8 2.7e-18 66.1 1.8 2.4 3 0 0 3 3 3 1 Ribosomal protein L7/L12 C-terminal domain Ribosomal_L12_N PF16320.5 KFY03547.1 - 2.7e-14 52.6 1.4 1.3e-13 50.5 0.1 2.7 3 1 0 3 3 3 1 Ribosomal protein L7/L12 dimerisation domain SpoVIF PF14069.6 KFY03547.1 - 0.051 13.3 0.3 0.24 11.2 0.1 2.1 2 1 0 2 2 2 0 Stage VI sporulation protein F AAA_5 PF07728.14 KFY03548.1 - 3.2e-123 406.2 0.0 1.3e-20 73.8 0.0 9.6 9 0 0 9 9 9 9 AAA domain (dynein-related subfamily) AAA_lid_7 PF17867.1 KFY03548.1 - 2.5e-61 204.5 0.1 2e-25 89.0 0.0 5.5 5 0 0 5 5 4 4 Midasin AAA lid domain AAA_7 PF12775.7 KFY03548.1 - 1.5e-32 112.5 1.4 7.7e-06 25.5 0.1 7.3 6 1 0 6 6 6 6 P-loop containing dynein motor region AAA_lid_5 PF17865.1 KFY03548.1 - 2.4e-32 111.2 0.8 3.1e-31 107.6 0.1 2.8 2 0 0 2 2 2 1 Midasin AAA lid domain AAA_16 PF13191.6 KFY03548.1 - 1.6e-30 106.7 17.2 1.1e-05 25.9 0.1 9.2 8 1 0 8 8 6 6 AAA ATPase domain AAA_3 PF07726.11 KFY03548.1 - 1.5e-28 99.2 0.0 7.8e-11 42.0 0.0 8.0 8 0 0 8 8 8 2 ATPase family associated with various cellular activities (AAA) AAA PF00004.29 KFY03548.1 - 3.7e-27 95.3 0.0 0.00044 20.7 0.0 7.4 7 0 0 7 7 6 6 ATPase family associated with various cellular activities (AAA) AAA_6 PF12774.7 KFY03548.1 - 1.5e-26 93.2 0.1 0.0014 17.7 0.0 8.5 8 1 0 8 8 8 6 Hydrolytic ATP binding site of dynein motor region AAA_22 PF13401.6 KFY03548.1 - 1.8e-24 86.6 2.8 0.0024 18.1 0.0 9.1 9 0 0 9 9 7 5 AAA domain Dynein_heavy PF03028.15 KFY03548.1 - 1.2e-23 83.5 0.0 0.0013 18.8 0.0 8.5 9 1 0 9 9 7 4 Dynein heavy chain region D6 P-loop domain AAA_33 PF13671.6 KFY03548.1 - 1.9e-21 76.7 0.0 0.026 14.7 0.0 7.2 6 0 0 6 6 6 5 AAA domain Sigma54_activat PF00158.26 KFY03548.1 - 4.1e-20 72.2 0.2 0.039 13.7 0.0 6.7 6 0 0 6 6 6 5 Sigma-54 interaction domain TsaE PF02367.17 KFY03548.1 - 1.9e-17 63.4 3.1 0.016 15.2 0.1 6.8 6 0 0 6 6 6 4 Threonylcarbamoyl adenosine biosynthesis protein TsaE ABC_tran PF00005.27 KFY03548.1 - 2.2e-17 63.9 3.6 0.0074 16.8 0.0 7.5 7 0 0 7 7 6 3 ABC transporter AAA_18 PF13238.6 KFY03548.1 - 3.2e-17 63.3 0.5 0.043 14.4 0.0 7.2 6 0 0 6 6 6 2 AAA domain AAA_14 PF13173.6 KFY03548.1 - 4.4e-17 62.4 0.0 0.022 14.8 0.0 7.6 7 0 0 7 7 6 3 AAA domain RsgA_GTPase PF03193.16 KFY03548.1 - 6e-17 62.1 0.8 0.029 14.3 0.0 6.2 6 0 0 6 6 6 4 RsgA GTPase AAA_30 PF13604.6 KFY03548.1 - 6.5e-17 61.9 0.5 0.0046 16.7 0.0 7.4 6 1 0 6 6 6 2 AAA domain RNA_helicase PF00910.22 KFY03548.1 - 5.1e-15 55.8 5.1 0.12 12.8 0.0 7.6 7 0 0 7 7 7 3 RNA helicase NACHT PF05729.12 KFY03548.1 - 7.7e-14 51.9 4.6 0.2 11.6 0.1 6.1 5 0 0 5 5 5 4 NACHT domain Sigma54_activ_2 PF14532.6 KFY03548.1 - 4.4e-13 49.5 0.5 0.0015 18.7 0.0 6.5 6 0 0 6 6 6 2 Sigma-54 interaction domain Rad17 PF03215.15 KFY03548.1 - 4e-12 46.5 0.2 0.34 10.8 0.0 6.5 6 0 0 6 6 6 2 Rad17 P-loop domain Zeta_toxin PF06414.12 KFY03548.1 - 2.8e-11 43.1 4.3 0.89 8.8 0.0 7.4 7 0 0 7 7 7 2 Zeta toxin T2SSE PF00437.20 KFY03548.1 - 6.1e-11 41.9 1.9 0.16 11.0 0.0 6.4 6 0 0 6 6 6 2 Type II/IV secretion system protein AAA_29 PF13555.6 KFY03548.1 - 7.1e-11 41.7 0.6 0.28 10.9 0.0 6.5 6 0 0 6 6 6 1 P-loop containing region of AAA domain RuvB_N PF05496.12 KFY03548.1 - 1.8e-10 40.8 5.2 0.022 14.5 0.0 7.0 8 0 0 8 8 7 2 Holliday junction DNA helicase RuvB P-loop domain IstB_IS21 PF01695.17 KFY03548.1 - 6.1e-10 39.1 0.2 0.52 10.0 0.0 6.1 6 0 0 6 6 6 2 IstB-like ATP binding protein AAA_19 PF13245.6 KFY03548.1 - 1.8e-09 38.1 2.4 1.2 9.4 0.1 6.9 6 0 0 6 6 5 1 AAA domain ATPase_2 PF01637.18 KFY03548.1 - 3e-09 37.1 0.0 0.94 9.3 0.0 6.8 7 0 0 7 7 6 1 ATPase domain predominantly from Archaea TniB PF05621.11 KFY03548.1 - 3.1e-09 36.5 0.1 1.2 8.5 0.0 6.3 6 0 0 6 6 6 1 Bacterial TniB protein AAA_25 PF13481.6 KFY03548.1 - 5.2e-09 36.0 1.1 1.6 8.2 0.0 5.9 5 0 0 5 5 5 1 AAA domain Mg_chelatase PF01078.21 KFY03548.1 - 1e-08 34.8 2.0 6.6 6.1 0.0 7.8 8 0 0 8 8 7 0 Magnesium chelatase, subunit ChlI AAA_28 PF13521.6 KFY03548.1 - 3.3e-08 33.9 10.9 0.34 11.2 0.1 7.5 8 0 0 8 8 6 1 AAA domain MMR_HSR1 PF01926.23 KFY03548.1 - 3.4e-08 33.6 2.1 4.7 7.3 0.0 6.6 6 0 0 6 6 6 0 50S ribosome-binding GTPase DUF815 PF05673.13 KFY03548.1 - 3.8e-08 32.8 1.9 2.5 7.2 0.0 5.7 6 0 0 6 6 5 0 Protein of unknown function (DUF815) AAA_24 PF13479.6 KFY03548.1 - 5.6e-08 32.7 0.1 4.3 7.0 0.0 6.0 6 0 0 6 6 5 0 AAA domain SRP54 PF00448.22 KFY03548.1 - 6.2e-08 32.5 5.1 0.88 9.2 0.1 5.6 6 0 0 6 6 5 2 SRP54-type protein, GTPase domain PduV-EutP PF10662.9 KFY03548.1 - 7.7e-08 32.2 3.2 0.043 13.6 0.0 5.4 6 0 0 6 6 5 2 Ethanolamine utilisation - propanediol utilisation Viral_helicase1 PF01443.18 KFY03548.1 - 1.4e-07 31.5 0.1 1.3 8.7 0.0 6.1 6 0 0 6 6 6 1 Viral (Superfamily 1) RNA helicase Roc PF08477.13 KFY03548.1 - 7.5e-07 29.4 4.1 9.2 6.5 0.1 6.3 6 0 0 6 6 6 0 Ras of Complex, Roc, domain of DAPkinase NTPase_1 PF03266.15 KFY03548.1 - 3.7e-06 27.0 6.3 1.6 8.6 0.0 5.9 6 0 0 6 6 5 2 NTPase dNK PF01712.19 KFY03548.1 - 1.7e-05 24.8 4.5 8.8 6.1 0.1 5.7 6 0 0 6 6 5 0 Deoxynucleoside kinase CbiA PF01656.23 KFY03548.1 - 4.2e-05 23.6 0.4 8.8 6.4 0.1 6.0 6 1 0 6 6 5 0 CobQ/CobB/MinD/ParA nucleotide binding domain Thymidylate_kin PF02223.17 KFY03548.1 - 5.1e-05 23.0 0.2 3.5 7.3 0.0 5.6 5 0 0 5 5 5 0 Thymidylate kinase ResIII PF04851.15 KFY03548.1 - 5.8e-05 23.2 1.0 2 8.4 0.0 4.6 5 0 0 5 5 3 1 Type III restriction enzyme, res subunit TIP49 PF06068.13 KFY03548.1 - 7.6e-05 22.1 3.5 0.73 9.0 0.1 4.9 6 0 0 6 6 4 1 TIP49 P-loop domain cobW PF02492.19 KFY03548.1 - 8.4e-05 22.2 5.0 9.9 5.7 0.0 5.7 6 0 0 6 6 6 0 CobW/HypB/UreG, nucleotide-binding domain AAA_17 PF13207.6 KFY03548.1 - 0.00013 22.4 7.0 2.6 8.5 0.0 6.1 6 0 0 6 6 5 0 AAA domain Bac_DnaA PF00308.18 KFY03548.1 - 0.00016 21.6 3.8 21 4.9 0.0 6.0 7 0 0 7 7 4 0 Bacterial dnaA protein PRK PF00485.18 KFY03548.1 - 0.00061 19.6 0.8 3.6 7.3 0.0 5.2 5 0 0 5 5 5 0 Phosphoribulokinase / Uridine kinase family ATPase PF06745.13 KFY03548.1 - 0.0013 18.2 0.1 16 4.7 0.0 4.6 4 0 0 4 4 4 0 KaiC DAP3 PF10236.9 KFY03548.1 - 0.0016 17.6 0.7 6.8 5.8 0.0 4.1 4 0 0 4 4 4 0 Mitochondrial ribosomal death-associated protein 3 PhoH PF02562.16 KFY03548.1 - 0.0033 16.9 1.0 13 5.2 0.0 4.7 5 0 0 5 5 5 0 PhoH-like protein Septin PF00735.18 KFY03548.1 - 0.0034 16.7 1.2 12 5.0 0.0 5.2 6 0 0 6 6 6 0 Septin NB-ARC PF00931.22 KFY03548.1 - 0.0053 16.0 5.1 24 4.0 0.1 5.4 6 0 0 6 6 5 0 NB-ARC domain ATP_bind_1 PF03029.17 KFY03548.1 - 0.0079 16.0 7.7 7.3 6.3 0.1 5.6 6 0 0 6 6 5 0 Conserved hypothetical ATP binding protein GAF_2 PF13185.6 KFY03548.1 - 0.0098 16.2 0.0 0.15 12.4 0.0 3.2 3 0 0 3 3 1 1 GAF domain FtsK_SpoIIIE PF01580.18 KFY03548.1 - 0.012 15.0 3.4 13 5.0 0.1 5.0 5 0 0 5 5 5 0 FtsK/SpoIIIE family Cytidylate_kin PF02224.18 KFY03548.1 - 0.016 14.9 2.1 7 6.3 0.1 4.7 5 0 0 5 5 5 0 Cytidylate kinase Ploopntkinase3 PF18751.1 KFY03548.1 - 0.019 14.9 0.3 14 5.5 0.0 4.1 4 0 0 4 4 4 0 P-loop Nucleotide Kinase3 AAA_9 PF12781.7 KFY03548.1 - 0.02 14.0 0.0 3.3 6.8 0.0 4.3 6 0 0 6 6 4 0 ATP-binding dynein motor region G-alpha PF00503.20 KFY03548.1 - 0.055 12.6 0.4 7.5 5.6 0.0 4.0 4 0 0 4 4 3 0 G-protein alpha subunit Ras PF00071.22 KFY03548.1 - 0.059 13.0 1.9 40 3.8 0.0 4.6 5 0 0 5 5 4 0 Ras family FAA_hydro_N_2 PF18288.1 KFY03548.1 - 0.06 13.8 0.6 1.7 9.1 0.3 3.4 3 0 0 3 3 2 0 Fumarylacetoacetase N-terminal domain 2 tRNA_lig_kinase PF08303.11 KFY03548.1 - 0.066 13.3 0.1 0.38 10.8 0.0 2.4 2 0 0 2 2 1 0 tRNA ligase kinase domain AAA_8 PF12780.7 KFY03548.1 - 0.066 12.5 0.0 15 4.8 0.0 3.5 3 0 0 3 3 2 0 P-loop containing dynein motor region D4 AAA_21 PF13304.6 KFY03548.1 - 0.089 12.6 0.9 2.6 7.8 0.0 3.6 4 0 0 4 4 3 0 AAA domain, putative AbiEii toxin, Type IV TA system MobB PF03205.14 KFY03548.1 - 0.1 12.5 5.0 48 3.8 0.0 5.3 6 0 0 6 6 5 0 Molybdopterin guanine dinucleotide synthesis protein B KTI12 PF08433.10 KFY03548.1 - 0.12 11.8 1.8 17 4.7 0.0 4.9 6 0 0 6 6 5 0 Chromatin associated protein KTI12 TrwB_AAD_bind PF10412.9 KFY03548.1 - 0.12 11.3 2.0 28 3.5 0.0 3.9 4 0 0 4 4 3 0 Type IV secretion-system coupling protein DNA-binding domain Guanylate_kin PF00625.21 KFY03548.1 - 0.16 11.6 0.7 16 5.1 0.0 4.1 4 0 0 4 4 4 0 Guanylate kinase MeaB PF03308.16 KFY03548.1 - 0.17 10.9 1.8 17 4.3 0.1 3.2 3 0 0 3 3 3 0 Methylmalonyl Co-A mutase-associated GTPase MeaB APS_kinase PF01583.20 KFY03548.1 - 0.58 10.0 2.6 15 5.5 0.0 4.3 5 0 0 5 5 3 0 Adenylylsulphate kinase Dynamin_N PF00350.23 KFY03548.1 - 6.7 6.7 5.8 16 5.5 0.0 4.2 5 0 0 5 5 2 0 Dynamin family Sugar_tr PF00083.24 KFY03549.1 - 1.6e-81 274.5 20.7 2.2e-81 274.1 20.7 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KFY03549.1 - 3.8e-30 105.0 27.1 3.8e-30 105.0 27.1 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 KFY03549.1 - 0.00023 19.7 3.7 0.00036 19.1 3.7 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_3 PF05977.13 KFY03549.1 - 0.1 10.9 2.9 0.18 10.2 2.9 1.3 1 0 0 1 1 1 0 Transmembrane secretion effector Glyco_hydro_43 PF04616.14 KFY03550.1 - 8.2e-55 186.1 3.7 1.1e-54 185.7 3.7 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 GH43_C2 PF17851.1 KFY03550.1 - 3.4e-20 72.6 0.0 4.7e-20 72.2 0.0 1.2 1 0 0 1 1 1 1 Beta xylosidase C-terminal Concanavalin A-like domain DUF4178 PF13785.6 KFY03550.1 - 0.018 15.1 0.2 0.046 13.8 0.2 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4178) Lipoprotein_3 PF00938.17 KFY03550.1 - 0.11 12.7 0.0 0.21 11.8 0.0 1.4 1 0 0 1 1 1 0 Lipoprotein FCH PF00611.23 KFY03563.1 - 1.9e-12 47.3 0.0 2.1e-12 47.1 0.0 1.1 1 0 0 1 1 1 1 Fes/CIP4, and EFC/F-BAR homology domain Not1 PF04054.15 KFY03564.1 - 2e-140 467.9 0.0 4.5e-140 466.8 0.0 1.6 1 0 0 1 1 1 1 CCR4-Not complex component, Not1 CNOT1_CAF1_bind PF16415.5 KFY03564.1 - 4.8e-95 317.2 2.8 9.9e-95 316.2 2.8 1.5 1 0 0 1 1 1 1 CCR4-NOT transcription complex subunit 1 CAF1-binding domain DUF3819 PF12842.7 KFY03564.1 - 1.8e-46 157.7 6.1 4.4e-46 156.4 6.1 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF3819) CNOT1_TTP_bind PF16417.5 KFY03564.1 - 2.7e-43 147.3 0.0 1.2e-42 145.3 0.0 2.1 1 0 0 1 1 1 1 CCR4-NOT transcription complex subunit 1 TTP binding domain CNOT1_HEAT PF16418.5 KFY03564.1 - 1.7e-34 119.1 0.3 5.2e-34 117.5 0.3 2.0 1 0 0 1 1 1 1 CCR4-NOT transcription complex subunit 1 HEAT repeat NTF2 PF02136.20 KFY03566.1 - 2.4e-29 102.3 0.0 3.8e-29 101.7 0.0 1.3 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain Mtr2 PF10429.9 KFY03566.1 - 0.11 12.4 0.0 0.12 12.3 0.0 1.2 1 0 0 1 1 1 0 Nuclear pore RNA shuttling protein Mtr2 Cg6151-P PF10233.9 KFY03567.1 - 4.5e-42 142.9 14.3 5.4e-42 142.7 14.3 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein CG6151-P DUF3566 PF12089.8 KFY03567.1 - 0.18 12.1 5.9 0.25 11.7 5.2 1.6 1 1 0 1 1 1 0 Transmembrane domain of unknown function (DUF3566) Dpy19 PF10034.9 KFY03567.1 - 1.2 7.2 9.4 1.5 7.0 9.4 1.0 1 0 0 1 1 1 0 Q-cell neuroblast polarisation DUF2721 PF11026.8 KFY03567.1 - 6.1 6.7 13.4 10 6.0 7.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2721) Ion_trans PF00520.31 KFY03571.1 - 5.8e-118 392.5 89.0 4.7e-40 137.4 9.0 5.0 4 1 0 4 4 4 4 Ion transport protein EF-hand_1 PF00036.32 KFY03571.1 - 3.1e-05 23.2 0.0 8.7e-05 21.8 0.0 1.9 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.6 KFY03571.1 - 0.00053 19.7 0.0 0.002 17.9 0.0 2.0 1 0 0 1 1 1 1 EF-hand domain EF-hand_7 PF13499.6 KFY03571.1 - 0.0031 17.9 0.0 0.0081 16.6 0.0 1.7 1 0 0 1 1 1 1 EF-hand domain pair GPHH PF16905.5 KFY03571.1 - 0.0081 15.9 0.0 0.017 14.8 0.0 1.6 1 0 0 1 1 1 1 Voltage-dependent L-type calcium channel, IQ-associated ADH_zinc_N_2 PF13602.6 KFY03573.1 - 1.8e-24 87.3 0.0 3.6e-24 86.3 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 KFY03573.1 - 1.6e-12 47.6 0.0 2.5e-12 46.9 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Cupin_2 PF07883.11 KFY03574.1 - 1.3e-09 37.7 0.0 2e-09 37.0 0.0 1.3 1 0 0 1 1 1 1 Cupin domain Cupin_1 PF00190.22 KFY03574.1 - 0.017 14.7 0.1 0.027 14.1 0.1 1.4 1 1 0 1 1 1 0 Cupin CDO_I PF05995.12 KFY03574.1 - 0.02 14.2 0.0 0.25 10.6 0.0 2.1 1 1 0 1 1 1 0 Cysteine dioxygenase type I RNA_ligase PF09414.10 KFY03575.1 - 2.8e-27 96.0 0.1 4.9e-27 95.2 0.1 1.3 1 0 0 1 1 1 1 RNA ligase AAA_33 PF13671.6 KFY03575.1 - 1.5e-12 47.9 0.0 1.1e-05 25.6 0.0 2.5 1 1 1 2 2 2 2 AAA domain AAA_22 PF13401.6 KFY03575.1 - 0.0039 17.5 0.0 0.0081 16.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.6 KFY03575.1 - 0.011 16.0 0.0 0.02 15.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA PF00004.29 KFY03575.1 - 0.035 14.5 0.0 0.065 13.7 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF1325 PF07039.11 KFY03581.1 - 4e-34 117.5 0.0 5.5e-34 117.1 0.0 1.1 1 0 0 1 1 1 1 SGF29 tudor-like domain DUF4537 PF15057.6 KFY03581.1 - 0.054 13.5 0.1 0.18 11.8 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4537) Nucleoporin_FG PF13634.6 KFY03582.1 - 0.018 15.9 11.1 0.018 15.9 11.1 14.4 4 3 9 13 13 13 0 Nucleoporin FG repeat region Ran_BP1 PF00638.18 KFY03582.1 - 0.11 12.7 0.0 0.27 11.5 0.0 1.6 1 0 0 1 1 1 0 RanBP1 domain Ku_C PF03730.14 KFY03582.1 - 6.3 7.6 9.6 0.36 11.5 2.0 2.6 2 0 0 2 2 2 0 Ku70/Ku80 C-terminal arm CENP-X PF09415.10 KFY03585.1 - 0.4 11.0 3.1 1.1 9.7 0.9 2.6 2 0 0 2 2 2 0 CENP-S associating Centromere protein X DUF3678 PF12435.8 KFY03586.1 - 1.4 8.3 7.4 0.52 9.7 0.4 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF3678) Glyco_tranf_2_4 PF13704.6 KFY03587.1 - 1e-08 35.6 1.1 2.1e-08 34.6 1.1 1.6 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_transf_92 PF01697.27 KFY03587.1 - 3.7e-08 33.3 0.1 9.9e-08 31.9 0.1 1.7 1 1 0 1 1 1 1 Glycosyltransferase family 92 DUF4916 PF16262.5 KFY03587.1 - 0.045 13.3 0.0 0.072 12.6 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4916) RRF PF01765.19 KFY03594.1 - 1.4e-32 112.9 0.3 1.8e-32 112.5 0.3 1.1 1 0 0 1 1 1 1 Ribosome recycling factor HSP70 PF00012.20 KFY03594.1 - 3.2e-13 48.7 0.2 5.5e-13 48.0 0.1 1.5 1 1 0 1 1 1 1 Hsp70 protein HSP70 PF00012.20 KFY03595.1 - 5.6e-20 71.1 7.0 6e-20 71.0 7.0 1.0 1 0 0 1 1 1 1 Hsp70 protein ATP-synt_DE PF00401.20 KFY03595.1 - 0.02 15.1 1.7 0.09 13.1 1.6 2.0 1 1 0 1 1 1 0 ATP synthase, Delta/Epsilon chain, long alpha-helix domain zf-C2H2 PF00096.26 KFY03596.1 - 0.058 13.9 0.5 0.058 13.9 0.5 1.6 2 0 0 2 2 2 0 Zinc finger, C2H2 type DUF2841 PF11001.8 KFY03597.1 - 3e-38 130.6 0.2 4.8e-38 130.0 0.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2841) EIN3 PF04873.13 KFY03597.1 - 0.054 12.8 0.1 0.11 11.7 0.1 1.5 1 0 0 1 1 1 0 Ethylene insensitive 3 Orbi_NS3 PF01616.16 KFY03598.1 - 0.5 10.0 8.9 16 5.2 0.9 3.4 1 1 3 4 4 4 0 Orbivirus NS3 Catalase PF00199.19 KFY03599.1 - 2.7e-171 569.9 0.3 3.4e-171 569.6 0.3 1.1 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.12 KFY03599.1 - 5.1e-17 61.8 0.0 1.1e-16 60.7 0.0 1.6 1 0 0 1 1 1 1 Catalase-related immune-responsive Catalase_C PF18011.1 KFY03599.1 - 2e-13 50.2 0.7 4.3e-13 49.2 0.7 1.6 1 0 0 1 1 1 1 C-terminal domain found in long catalases DJ-1_PfpI PF01965.24 KFY03599.1 - 4.7e-13 49.3 0.1 8.7e-13 48.4 0.1 1.5 1 0 0 1 1 1 1 DJ-1/PfpI family Glyco_hydro_28 PF00295.17 KFY03600.1 - 3.4e-101 338.5 23.4 3.8e-101 338.4 23.4 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 Nup192 PF11894.8 KFY03602.1 - 0 1380.1 11.9 0 1379.7 11.9 1.1 1 0 0 1 1 1 1 Nuclear pore complex scaffold, nucleoporins 186/192/205 Cullin PF00888.22 KFY03602.1 - 8.6e-166 553.1 7.2 1.6e-165 552.3 7.2 1.4 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 KFY03602.1 - 2e-24 85.4 0.6 8.7e-24 83.3 0.6 2.2 1 0 0 1 1 1 1 Cullin protein neddylation domain PI3_PI4_kinase PF00454.27 KFY03603.1 - 2.8e-54 184.6 0.0 1.2e-53 182.5 0.0 2.0 2 0 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase TAN PF11640.8 KFY03603.1 - 5.6e-40 136.9 1.7 6.8e-39 133.4 0.3 3.3 2 0 0 2 2 2 1 Telomere-length maintenance and DNA damage repair FATC PF02260.20 KFY03603.1 - 2.2e-11 43.4 0.2 2.2e-10 40.2 0.0 2.5 2 0 0 2 2 2 1 FATC domain FAT PF02259.23 KFY03603.1 - 4.8e-08 32.6 3.9 1.1e-07 31.4 3.9 1.6 1 0 0 1 1 1 1 FAT domain CSG2 PF16965.5 KFY03603.1 - 0.071 12.1 0.1 0.16 10.9 0.1 1.5 1 0 0 1 1 1 0 Ceramide synthase regulator UPF0052 PF01933.18 KFY03604.1 - 2.8e-59 200.7 0.0 3.4e-59 200.5 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family UPF0052 zf-C3HC4_3 PF13920.6 KFY03605.1 - 2.1e-11 43.5 5.2 3.1e-11 43.0 5.2 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 KFY03605.1 - 9.9e-09 34.9 6.6 1.7e-08 34.2 6.6 1.3 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4 PF00097.25 KFY03605.1 - 1.5e-08 34.3 6.5 2.4e-08 33.7 6.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 KFY03605.1 - 6.3e-08 32.3 8.6 1e-07 31.6 8.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 KFY03605.1 - 3.8e-07 30.3 7.5 5.9e-07 29.7 7.5 1.3 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 KFY03605.1 - 4.5e-07 29.7 7.3 7.3e-07 29.1 7.3 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 KFY03605.1 - 4.5e-05 23.4 2.6 4.5e-05 23.4 2.6 1.9 1 1 1 2 2 2 1 RING-type zinc-finger zf-RING_4 PF14570.6 KFY03605.1 - 0.00072 19.3 4.4 0.0014 18.4 4.4 1.4 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-rbx1 PF12678.7 KFY03605.1 - 0.00093 19.4 4.8 0.0018 18.5 4.8 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 KFY03605.1 - 0.0026 17.8 3.1 0.0043 17.1 3.1 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_6 PF14835.6 KFY03605.1 - 0.0049 16.7 1.6 0.0083 16.0 1.6 1.4 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-C3HC4_4 PF15227.6 KFY03605.1 - 0.0098 16.0 6.4 0.02 15.1 6.4 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING Baculo_IE-1 PF05290.11 KFY03605.1 - 0.06 13.3 0.2 0.085 12.8 0.2 1.2 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) RR_TM4-6 PF06459.12 KFY03605.1 - 0.21 11.4 2.4 0.33 10.7 2.4 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Ribosomal_L16 PF00252.18 KFY03606.1 - 3.4e-39 133.9 0.7 4.4e-39 133.5 0.7 1.1 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e DNApol_Exo PF18136.1 KFY03607.1 - 6.9e-105 350.2 0.0 1.1e-104 349.5 0.0 1.3 1 0 0 1 1 1 1 DNA mitochondrial polymerase exonuclease domain DNA_pol_A PF00476.20 KFY03607.1 - 8.9e-59 199.4 0.0 1.6e-58 198.6 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase family A GFO_IDH_MocA PF01408.22 KFY03608.1 - 3.5e-17 63.3 0.1 6.7e-17 62.4 0.1 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 KFY03608.1 - 0.00068 19.6 0.0 0.0014 18.7 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain Semialdhyde_dh PF01118.24 KFY03608.1 - 0.097 13.1 0.1 0.31 11.5 0.0 1.8 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain Adap_comp_sub PF00928.21 KFY03609.1 - 5.4e-85 285.0 0.0 7.4e-85 284.5 0.0 1.2 1 0 0 1 1 1 1 Adaptor complexes medium subunit family PLAC8 PF04749.17 KFY03609.1 - 9.1e-15 55.5 12.7 1.9e-14 54.5 12.7 1.6 1 0 0 1 1 1 1 PLAC8 family Clat_adaptor_s PF01217.20 KFY03609.1 - 3e-05 24.0 0.2 5.6e-05 23.1 0.2 1.4 1 0 0 1 1 1 1 Clathrin adaptor complex small chain RIBIOP_C PF04950.12 KFY03609.1 - 0.0083 15.6 0.0 0.038 13.4 0.0 1.9 2 0 0 2 2 2 1 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal CorA PF01544.18 KFY03610.1 - 1.7e-14 53.8 0.2 2.5e-14 53.3 0.2 1.1 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein peroxidase PF00141.23 KFY03613.1 - 9.3e-47 159.6 0.0 1.3e-46 159.2 0.0 1.2 1 0 0 1 1 1 1 Peroxidase Lipase_3 PF01764.25 KFY03614.1 - 1.2e-09 38.1 0.0 1.9e-09 37.6 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.7 KFY03614.1 - 0.0023 18.6 0.0 0.003 18.2 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family TGBp3 PF02495.17 KFY03614.1 - 0.093 12.4 0.0 0.29 10.8 0.0 1.8 2 0 0 2 2 2 0 Triple gene block 3 Glyco_hydro_76 PF03663.14 KFY03615.1 - 6.4e-35 121.3 0.0 7.5e-35 121.1 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 VMA21 PF09446.10 KFY03615.1 - 0.031 14.4 0.2 0.056 13.5 0.2 1.5 1 0 0 1 1 1 0 VMA21-like domain Sugar_tr PF00083.24 KFY03617.1 - 1e-118 397.1 20.4 1.7e-118 396.4 20.4 1.3 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KFY03617.1 - 5.4e-30 104.5 49.3 6.2e-25 87.9 23.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily peroxidase PF00141.23 KFY03618.1 - 6.9e-84 281.1 0.0 9.3e-49 166.2 0.0 2.2 2 0 0 2 2 2 2 Peroxidase Herpes_U59 PF04529.12 KFY03618.1 - 0.097 11.7 0.0 0.19 10.8 0.0 1.3 1 0 0 1 1 1 0 Herpesvirus U59 protein CN_hydrolase PF00795.22 KFY03619.1 - 3.9e-35 121.5 0.0 6.8e-35 120.7 0.0 1.3 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase CFEM PF05730.11 KFY03620.1 - 3.4e-08 33.5 9.8 3.4e-08 33.5 9.8 1.9 2 0 0 2 2 2 1 CFEM domain Zn_clus PF00172.18 KFY03620.1 - 0.00039 20.5 11.2 0.00077 19.5 11.2 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.16 KFY03621.1 - 4.2e-41 141.1 60.6 2.9e-40 138.3 59.8 2.3 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 KFY03621.1 - 2.4e-13 49.4 20.0 3.6e-13 48.8 19.6 1.4 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) OATP PF03137.20 KFY03621.1 - 0.00025 19.5 2.4 0.00025 19.5 2.4 2.6 3 0 0 3 3 3 1 Organic Anion Transporter Polypeptide (OATP) family Pkinase PF00069.25 KFY03623.1 - 8.9e-27 94.1 0.0 1e-25 90.7 0.0 2.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFY03623.1 - 8.4e-10 38.4 0.1 1.5e-08 34.3 0.1 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.22 KFY03623.1 - 0.00073 19.2 0.0 0.0012 18.5 0.0 1.2 1 0 0 1 1 1 1 RIO1 family Pkinase_fungal PF17667.1 KFY03623.1 - 0.18 10.6 0.0 0.25 10.1 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Sod_Cu PF00080.20 KFY03624.1 - 3.3e-46 157.0 5.4 3.7e-46 156.8 5.4 1.0 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) Tox-HNH-EHHH PF15657.6 KFY03624.1 - 0.41 11.1 4.4 0.091 13.1 1.1 1.7 2 0 0 2 2 2 0 HNH/Endo VII superfamily nuclease toxins Xan_ur_permease PF00860.20 KFY03626.1 - 2e-21 76.1 32.5 1e-20 73.8 32.5 2.2 1 1 0 1 1 1 1 Permease family QRPTase_N PF02749.16 KFY03627.1 - 1.8e-07 31.1 0.0 2.8e-07 30.5 0.0 1.3 1 0 0 1 1 1 1 Quinolinate phosphoribosyl transferase, N-terminal domain Mito_carr PF00153.27 KFY03630.1 - 6.3e-14 51.7 2.9 0.0003 20.7 0.1 4.9 3 2 0 3 3 3 3 Mitochondrial carrier protein DUF883 PF05957.13 KFY03630.1 - 0.28 11.8 0.5 0.73 10.5 0.5 1.7 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF883) Nop10p PF04135.12 KFY03631.1 - 2.2e-19 69.2 0.3 5.5e-19 68.0 0.3 1.7 1 0 0 1 1 1 1 Nucleolar RNA-binding protein, Nop10p family Pex14_N PF04695.13 KFY03631.1 - 0.048 14.3 1.5 0.1 13.2 1.5 1.6 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region TPR_10 PF13374.6 KFY03632.1 - 3.2e-33 112.7 0.0 1.2e-12 47.2 0.0 3.2 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_12 PF13424.6 KFY03632.1 - 5.1e-23 81.2 0.0 2.6e-10 40.5 0.0 3.0 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_7 PF13176.6 KFY03632.1 - 3.2e-07 29.9 0.0 0.00074 19.4 0.0 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_17 PF13431.6 KFY03632.1 - 4.5e-05 23.6 0.0 0.1 13.1 0.0 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.17 KFY03632.1 - 0.0003 20.7 0.0 0.38 11.0 0.0 3.0 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.28 KFY03632.1 - 0.0042 16.8 0.0 0.22 11.4 0.0 2.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_5 PF12688.7 KFY03632.1 - 0.014 15.6 0.0 0.02 15.1 0.0 1.3 1 0 0 1 1 1 0 Tetratrico peptide repeat TPR_16 PF13432.6 KFY03632.1 - 0.021 15.5 0.0 3.5 8.4 0.0 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_4 PF07721.14 KFY03632.1 - 0.11 13.2 0.1 2.5 9.0 0.0 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_8 PF13181.6 KFY03632.1 - 0.13 12.5 0.0 16 6.0 0.0 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat partial_CstF PF15861.5 KFY03632.1 - 0.14 12.0 0.6 0.48 10.3 0.1 2.2 2 1 0 2 2 2 0 Partial cleavage stimulation factor domain Presenilin PF01080.17 KFY03636.1 - 0.11 11.2 0.0 0.15 10.8 0.0 1.2 1 0 0 1 1 1 0 Presenilin Ank_2 PF12796.7 KFY03637.1 - 5.6e-54 180.7 0.1 9.3e-13 48.6 0.0 5.4 2 1 5 7 7 7 6 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KFY03637.1 - 2.1e-34 113.7 1.4 0.0046 17.3 0.0 9.8 10 0 0 10 10 10 7 Ankyrin repeat Ank PF00023.30 KFY03637.1 - 8.9e-31 105.0 15.3 0.00027 21.2 0.0 10.1 10 0 0 10 10 10 8 Ankyrin repeat Ank_4 PF13637.6 KFY03637.1 - 4.5e-29 100.5 0.1 3e-08 34.0 0.0 5.9 3 1 4 7 7 7 7 Ankyrin repeats (many copies) Ank_5 PF13857.6 KFY03637.1 - 8.8e-29 99.2 3.7 5.1e-06 26.7 0.0 7.3 3 3 3 7 7 7 7 Ankyrin repeats (many copies) DUF2384 PF09722.10 KFY03637.1 - 0.0092 16.0 0.1 50 4.0 0.0 4.5 4 0 0 4 4 4 0 Protein of unknown function (DUF2384) TRI12 PF06609.13 KFY03644.1 - 9.3e-98 328.2 24.8 1.2e-97 327.8 24.8 1.0 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.16 KFY03644.1 - 4.8e-19 68.5 47.4 4.8e-19 68.5 47.4 2.5 1 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KFY03644.1 - 2.2e-07 30.1 8.1 2.2e-07 30.1 8.1 3.5 2 2 1 3 3 3 2 Sugar (and other) transporter DUF3040 PF11239.8 KFY03644.1 - 0.13 12.5 0.2 0.13 12.5 0.2 3.8 3 0 0 3 3 3 0 Protein of unknown function (DUF3040) TMEM100 PF16311.5 KFY03644.1 - 0.15 11.7 0.1 7.5 6.1 0.0 2.8 2 0 0 2 2 2 0 Transmembrane protein 100 Pyr_redox_3 PF13738.6 KFY03645.1 - 8.1e-10 38.4 0.0 4.2e-07 29.5 0.0 3.3 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KFY03645.1 - 2.1e-08 33.8 0.0 0.00038 19.8 0.0 2.5 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 KFY03645.1 - 4.9e-07 28.5 0.0 1.8e-05 23.4 0.0 2.2 1 1 1 2 2 2 1 Flavin-binding monooxygenase-like Shikimate_DH PF01488.20 KFY03645.1 - 1.9e-06 28.0 0.0 0.0019 18.3 0.0 2.4 2 0 0 2 2 2 2 Shikimate / quinate 5-dehydrogenase NAD_binding_8 PF13450.6 KFY03645.1 - 4.3e-06 26.9 0.0 3.8e-05 23.8 0.0 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.6 KFY03645.1 - 9.3e-05 21.7 0.3 0.13 11.4 0.0 3.6 5 0 0 5 5 5 2 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.6 KFY03645.1 - 0.0014 18.6 0.3 0.18 11.8 0.1 3.4 4 0 0 4 4 4 1 FAD-NAD(P)-binding ThiF PF00899.21 KFY03645.1 - 0.0075 15.6 1.2 0.23 10.8 0.0 2.4 3 0 0 3 3 3 1 ThiF family DAO PF01266.24 KFY03645.1 - 0.017 14.7 1.6 1.6 8.2 0.2 3.2 2 1 1 3 3 3 0 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 KFY03645.1 - 0.072 12.2 0.0 0.13 11.3 0.0 1.4 1 0 0 1 1 1 0 FAD binding domain NAD_binding_2 PF03446.15 KFY03645.1 - 0.14 12.3 0.0 0.3 11.3 0.0 1.5 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase ADH_N PF08240.12 KFY03646.1 - 5.7e-21 74.4 3.8 1.7e-18 66.5 2.0 2.4 1 1 1 2 2 2 2 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KFY03646.1 - 1.7e-17 63.6 1.1 2.9e-17 62.9 1.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KFY03646.1 - 8.5e-11 43.0 0.2 2.1e-10 41.7 0.1 1.7 1 1 1 2 2 2 1 Zinc-binding dehydrogenase Qn_am_d_aII PF14930.6 KFY03646.1 - 0.1 12.9 0.1 0.32 11.3 0.0 1.8 2 0 0 2 2 2 0 Quinohemoprotein amine dehydrogenase, alpha subunit domain II Glu_dehyd_C PF16912.5 KFY03646.1 - 0.27 10.7 4.1 1.3 8.4 4.2 1.9 1 1 0 1 1 1 0 Glucose dehydrogenase C-terminus GST_N_4 PF17172.4 KFY03648.1 - 1.6e-23 83.3 0.0 3.1e-23 82.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase N-terminal domain GST_C_6 PF17171.4 KFY03648.1 - 3.9e-10 39.4 0.0 1.1e-09 37.9 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 KFY03648.1 - 1.5e-05 24.9 0.0 0.00073 19.5 0.1 2.6 2 1 0 2 2 2 1 Glutathione S-transferase, C-terminal domain Tom37 PF10568.9 KFY03648.1 - 1.7e-05 25.1 0.0 3.4e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 Outer mitochondrial membrane transport complex protein GST_N_3 PF13417.6 KFY03648.1 - 0.06 13.8 0.0 0.32 11.4 0.0 2.1 2 1 0 2 2 2 0 Glutathione S-transferase, N-terminal domain F-box-like PF12937.7 KFY03649.1 - 0.0015 18.4 0.0 0.0049 16.7 0.0 1.9 1 1 0 1 1 1 1 F-box-like F-box PF00646.33 KFY03649.1 - 0.11 12.5 0.2 14 5.7 0.0 2.9 3 0 0 3 3 3 0 F-box domain Acetyltransf_10 PF13673.7 KFY03651.1 - 7.1e-09 35.7 0.0 1.2e-08 35.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KFY03651.1 - 5e-05 23.6 0.0 8.2e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KFY03651.1 - 0.00012 22.3 0.1 0.00021 21.5 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_9 PF13527.7 KFY03651.1 - 0.0003 20.9 0.1 0.038 14.1 0.0 2.2 1 1 1 2 2 2 2 Acetyltransferase (GNAT) domain MOZ_SAS PF01853.18 KFY03651.1 - 0.063 12.9 0.0 0.092 12.4 0.0 1.2 1 0 0 1 1 1 0 MOZ/SAS family Acetyltransf_CG PF14542.6 KFY03651.1 - 0.099 12.8 0.0 0.29 11.3 0.0 1.8 2 0 0 2 2 2 0 GCN5-related N-acetyl-transferase FR47 PF08445.10 KFY03651.1 - 0.16 11.9 0.0 0.27 11.2 0.0 1.3 1 0 0 1 1 1 0 FR47-like protein Myb_DNA-binding PF00249.31 KFY03652.1 - 0.0085 16.3 0.0 0.024 14.8 0.0 1.8 1 0 0 1 1 1 1 Myb-like DNA-binding domain TRAM_LAG1_CLN8 PF03798.16 KFY03653.1 - 2.2e-33 115.7 11.9 2.2e-33 115.7 11.9 1.4 2 0 0 2 2 2 1 TLC domain DUF4818 PF16089.5 KFY03653.1 - 0.34 11.4 5.1 1.8 9.1 0.2 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4818) USP7_ICP0_bdg PF12436.8 KFY03654.1 - 3.3e-45 154.3 0.2 5.4e-45 153.6 0.2 1.3 1 0 0 1 1 1 1 ICP0-binding domain of Ubiquitin-specific protease 7 UCH PF00443.29 KFY03654.1 - 3.9e-36 124.9 0.0 5.9e-36 124.3 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase MATH PF00917.26 KFY03654.1 - 1.8e-08 34.5 0.1 7.1e-08 32.6 0.1 2.0 1 0 0 1 1 1 1 MATH domain UCH_1 PF13423.6 KFY03654.1 - 2.9e-06 27.1 0.0 2.6e-05 24.0 0.0 2.2 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase RPE65 PF03055.15 KFY03655.1 - 2.1e-85 287.6 0.5 2.7e-75 254.4 0.2 1.9 2 0 0 2 2 2 2 Retinal pigment epithelial membrane protein Zn_clus PF00172.18 KFY03656.1 - 6.9e-07 29.3 10.9 6.9e-07 29.3 10.9 1.7 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 KFY03656.1 - 2.6e-06 26.5 0.4 4.4e-06 25.8 0.4 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Cu-oxidase PF00394.22 KFY03657.1 - 2.5e-32 112.2 0.0 1.6e-31 109.6 0.0 2.1 2 1 0 2 2 2 1 Multicopper oxidase Cu-oxidase_3 PF07732.15 KFY03657.1 - 8.5e-30 103.2 0.8 3e-29 101.4 0.1 2.2 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 KFY03657.1 - 6.3e-27 94.0 7.3 5e-23 81.3 0.9 3.1 2 2 0 2 2 2 2 Multicopper oxidase Acetyltransf_10 PF13673.7 KFY03658.1 - 3.4e-08 33.5 0.0 4.7e-08 33.0 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KFY03658.1 - 7.4e-07 29.5 0.0 1.2e-06 28.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KFY03658.1 - 1.1e-05 25.7 0.0 1.3e-05 25.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_9 PF13527.7 KFY03658.1 - 0.00034 20.7 0.0 0.0017 18.4 0.0 2.0 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 KFY03658.1 - 0.03 14.4 0.0 0.087 13.0 0.0 1.8 2 0 0 2 2 2 0 GCN5-related N-acetyl-transferase MOZ_SAS PF01853.18 KFY03658.1 - 0.04 13.6 0.0 0.058 13.1 0.0 1.2 1 0 0 1 1 1 0 MOZ/SAS family FR47 PF08445.10 KFY03658.1 - 0.059 13.4 0.0 0.1 12.6 0.0 1.4 1 0 0 1 1 1 0 FR47-like protein Pyr_redox_2 PF07992.14 KFY03659.1 - 3.1e-48 164.5 0.7 3.8e-48 164.2 0.7 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KFY03659.1 - 2.2e-17 63.4 1.4 3.3e-15 56.4 0.5 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 KFY03659.1 - 4e-16 59.2 0.4 2.8e-14 53.1 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.6 KFY03659.1 - 2.1e-05 24.9 0.0 0.0045 17.4 0.0 2.6 2 0 0 2 2 2 1 Putative NAD(P)-binding NAD_binding_8 PF13450.6 KFY03659.1 - 3.1e-05 24.1 0.2 0.045 14.0 0.0 3.0 2 1 0 2 2 2 2 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 KFY03659.1 - 0.00012 21.4 0.1 0.00055 19.2 0.0 1.9 2 0 0 2 2 2 1 Thi4 family K_oxygenase PF13434.6 KFY03659.1 - 0.005 16.0 0.0 0.2 10.8 0.0 3.0 2 1 1 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.24 KFY03659.1 - 0.013 15.1 0.2 7.3 6.1 0.1 3.1 2 1 1 3 3 3 0 FAD dependent oxidoreductase GIDA PF01134.22 KFY03659.1 - 0.016 14.3 3.7 1.4 7.9 0.2 3.3 3 1 1 4 4 4 0 Glucose inhibited division protein A HI0933_like PF03486.14 KFY03659.1 - 0.041 12.6 0.4 0.73 8.5 0.1 2.7 3 0 0 3 3 3 0 HI0933-like protein FAD_binding_3 PF01494.19 KFY03659.1 - 0.044 13.0 0.9 3.1 7.0 0.1 2.5 2 1 0 2 2 2 0 FAD binding domain Trp_halogenase PF04820.14 KFY03659.1 - 0.065 12.1 0.1 0.61 8.9 0.0 2.3 3 0 0 3 3 3 0 Tryptophan halogenase Shikimate_DH PF01488.20 KFY03659.1 - 0.14 12.2 0.1 11 6.1 0.0 2.6 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase FAD_binding_2 PF00890.24 KFY03659.1 - 0.17 10.9 4.3 0.18 10.8 0.2 2.7 2 1 0 3 3 3 0 FAD binding domain KAR9 PF08580.10 KFY03660.1 - 0.11 11.0 8.6 0.12 10.9 8.6 1.0 1 0 0 1 1 1 0 Yeast cortical protein KAR9 DUF5427 PF10310.9 KFY03660.1 - 3.2 6.6 7.5 4 6.3 7.5 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5427) SOG2 PF10428.9 KFY03660.1 - 3.4 6.8 14.5 4.4 6.4 14.5 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein DUF2076 PF09849.9 KFY03660.1 - 6.3 6.8 8.7 22 5.0 8.7 1.8 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) Totivirus_coat PF05518.11 KFY03660.1 - 9.5 4.1 11.9 12 3.8 11.9 1.1 1 0 0 1 1 1 0 Totivirus coat protein WD40 PF00400.32 KFY03661.1 - 7.4e-07 29.8 16.7 0.04 14.8 0.4 6.4 7 0 0 7 7 7 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFY03661.1 - 0.0021 18.3 0.1 1.8 8.9 0.1 3.5 1 1 2 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain PHD PF00628.29 KFY03661.1 - 5.7 6.9 9.7 7.8 6.5 0.2 2.9 2 1 0 2 2 2 0 PHD-finger Kinesin PF00225.23 KFY03663.1 - 4e-56 190.4 0.0 5.6e-56 189.9 0.0 1.2 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 KFY03663.1 - 1.1e-08 35.2 0.0 1.9e-08 34.4 0.0 1.3 1 0 0 1 1 1 1 Microtubule binding AAA_22 PF13401.6 KFY03663.1 - 0.02 15.2 0.0 0.056 13.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain SAM_PNT PF02198.16 KFY03663.1 - 0.067 13.2 0.0 0.26 11.3 0.0 2.0 2 0 0 2 2 2 0 Sterile alpha motif (SAM)/Pointed domain AAA_16 PF13191.6 KFY03663.1 - 0.081 13.3 0.0 0.17 12.2 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain OPT PF03169.15 KFY03664.1 - 1.2e-130 437.1 47.6 1.3e-130 436.9 47.6 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein Metallophos PF00149.28 KFY03665.1 - 8.4e-19 68.9 0.4 1.4e-18 68.2 0.4 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_C PF14008.6 KFY03665.1 - 3e-17 63.2 1.4 3e-17 63.2 1.4 2.1 2 0 0 2 2 2 1 Iron/zinc purple acid phosphatase-like protein C Pur_ac_phosph_N PF16656.5 KFY03665.1 - 4.6e-16 59.2 2.6 5.3e-16 59.0 0.3 2.3 2 1 0 2 2 2 1 Purple acid Phosphatase, N-terminal domain PhoD_N PF16655.5 KFY03665.1 - 0.075 13.6 0.0 0.18 12.4 0.0 1.6 1 0 0 1 1 1 0 PhoD-like phosphatase, N-terminal domain fn3 PF00041.21 KFY03665.1 - 0.18 12.2 0.7 0.48 10.8 0.3 1.9 2 0 0 2 2 2 0 Fibronectin type III domain Peroxidase_2 PF01328.17 KFY03666.1 - 2.7e-45 155.2 0.0 5.1e-45 154.3 0.0 1.4 1 0 0 1 1 1 1 Peroxidase, family 2 HET PF06985.11 KFY03666.1 - 5.8e-27 94.8 0.1 1.1e-26 94.0 0.1 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) F-box PF00646.33 KFY03667.1 - 0.00019 21.2 0.2 0.00073 19.3 0.0 2.2 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.7 KFY03667.1 - 0.0031 17.4 0.4 0.0096 15.8 0.4 1.9 1 0 0 1 1 1 1 F-box-like HeLo PF14479.6 KFY03668.1 - 9.6e-10 38.6 0.1 1.7e-09 37.8 0.1 1.4 1 0 0 1 1 1 1 Prion-inhibition and propagation Pkinase PF00069.25 KFY03668.1 - 7.7e-05 22.2 0.0 0.00027 20.4 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFY03668.1 - 0.003 16.9 0.0 0.0067 15.8 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase TPR_12 PF13424.6 KFY03670.1 - 1.8e-65 217.2 40.2 2.5e-10 40.5 0.3 11.1 8 1 2 11 11 11 11 Tetratricopeptide repeat TPR_10 PF13374.6 KFY03670.1 - 1.7e-41 139.0 34.1 1.8e-05 24.5 0.6 16.1 17 0 0 17 17 17 9 Tetratricopeptide repeat Ank_2 PF12796.7 KFY03670.1 - 9.2e-36 122.3 0.6 3.5e-10 40.3 0.0 8.1 4 1 2 7 7 7 6 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KFY03670.1 - 1.9e-24 83.1 14.1 0.0092 16.4 0.0 12.2 12 0 0 12 12 12 4 Ankyrin repeat Ank_4 PF13637.6 KFY03670.1 - 8.2e-24 83.7 3.2 9.5e-06 26.1 0.0 8.5 5 2 5 10 10 10 5 Ankyrin repeats (many copies) Ank PF00023.30 KFY03670.1 - 4.2e-23 80.7 17.2 0.0035 17.7 0.0 11.3 12 0 0 12 12 11 6 Ankyrin repeat Pkinase PF00069.25 KFY03670.1 - 6.5e-20 71.6 0.0 1.3e-19 70.7 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFY03670.1 - 1.6e-18 66.9 0.0 3.3e-18 65.9 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Ank_5 PF13857.6 KFY03670.1 - 6.2e-16 58.3 4.7 0.0051 17.1 0.0 8.8 8 1 1 9 9 9 2 Ankyrin repeats (many copies) TPR_MalT PF17874.1 KFY03670.1 - 1.9e-05 24.2 21.1 0.49 9.7 2.9 4.7 2 1 2 5 5 5 4 MalT-like TPR region TPR_7 PF13176.6 KFY03670.1 - 0.00022 21.0 21.1 0.05 13.7 0.3 8.3 8 0 0 8 8 6 1 Tetratricopeptide repeat TPR_16 PF13432.6 KFY03670.1 - 0.012 16.3 19.3 1.1 10.0 0.5 7.2 8 1 0 8 8 6 0 Tetratricopeptide repeat Sel1 PF08238.12 KFY03670.1 - 0.02 15.6 0.1 0.088 13.5 0.1 2.2 1 0 0 1 1 1 0 Sel1 repeat TPR_2 PF07719.17 KFY03670.1 - 0.028 14.5 30.8 3.8 7.8 0.1 9.8 11 0 0 11 11 10 0 Tetratricopeptide repeat TPR_4 PF07721.14 KFY03670.1 - 0.033 14.8 1.0 23 6.0 0.0 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_19 PF14559.6 KFY03670.1 - 0.094 13.2 25.7 0.89 10.1 0.1 8.8 7 2 2 9 9 8 0 Tetratricopeptide repeat TPR_1 PF00515.28 KFY03670.1 - 0.56 10.1 26.9 3.8 7.5 0.0 7.9 9 0 0 9 9 9 0 Tetratricopeptide repeat Proteasome PF00227.26 KFY03674.1 - 4.2e-10 39.4 0.0 4.6e-10 39.3 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit E1-E2_ATPase PF00122.20 KFY03675.1 - 2.4e-49 167.3 7.5 2.8e-49 167.1 3.6 2.7 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 KFY03675.1 - 1.2e-46 158.7 10.3 1.9e-46 158.1 7.1 2.2 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 KFY03675.1 - 1.9e-23 83.9 3.4 1.4e-22 81.0 3.4 2.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 KFY03675.1 - 6.4e-21 74.2 0.0 1.2e-20 73.4 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 KFY03675.1 - 1.2e-18 66.5 0.2 3.8e-18 64.9 0.0 2.0 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 KFY03675.1 - 2e-08 34.3 0.7 2e-06 27.8 0.6 2.4 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 KFY03675.1 - 8e-06 26.4 0.0 2.4e-05 24.8 0.0 1.8 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase 14-3-3 PF00244.20 KFY03677.1 - 4.1e-108 360.0 1.6 6.1e-108 359.4 1.6 1.2 1 0 0 1 1 1 1 14-3-3 protein FlaC_arch PF05377.11 KFY03677.1 - 0.16 12.4 1.1 0.34 11.3 1.1 1.5 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) MitMem_reg PF13012.6 KFY03677.1 - 0.18 12.3 0.8 1 9.8 0.2 2.4 1 1 1 2 2 2 0 Maintenance of mitochondrial structure and function Acyl-CoA_dh_1 PF00441.24 KFY03680.1 - 3.1e-31 108.6 2.7 4.8e-31 108.0 2.7 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Cyt-b5 PF00173.28 KFY03680.1 - 1.6e-21 76.2 0.3 5.2e-21 74.6 0.3 1.9 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Acyl-CoA_dh_M PF02770.19 KFY03680.1 - 1.3e-16 60.5 0.4 2.8e-16 59.5 0.4 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 KFY03680.1 - 1.2e-10 42.1 0.2 1.6e-09 38.4 0.0 2.3 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 KFY03680.1 - 2.6e-08 34.2 0.3 6.1e-08 33.0 0.3 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain SNCAIP_SNCA_bd PF16700.5 KFY03680.1 - 0.025 14.3 0.5 0.053 13.2 0.1 1.7 2 0 0 2 2 2 0 Synphilin-1 alpha-Synuclein-binding domain FTA4 PF13093.6 KFY03681.1 - 2.9e-46 157.9 3.5 7.5e-45 153.3 3.5 2.0 1 1 0 1 1 1 1 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 RTA1 PF04479.13 KFY03682.1 - 2.9e-57 193.6 5.4 4e-57 193.2 5.4 1.2 1 0 0 1 1 1 1 RTA1 like protein UCR_UQCRX_QCR9 PF05365.12 KFY03682.1 - 0.039 13.9 0.4 0.14 12.1 0.4 1.9 1 0 0 1 1 1 0 Ubiquinol-cytochrome C reductase, UQCRX/QCR9 like Fungal_trans_2 PF11951.8 KFY03683.1 - 3e-09 36.2 4.7 4.2e-09 35.7 4.7 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KFY03683.1 - 8.6e-09 35.4 6.9 1.4e-08 34.7 6.9 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MPDZ_u10 PF16667.5 KFY03684.1 - 0.13 13.2 0.2 0.13 13.2 0.2 3.0 3 0 0 3 3 3 0 Unstructured region 10 on multiple PDZ protein DUF3619 PF12279.8 KFY03684.1 - 0.17 12.2 2.3 0.36 11.1 2.3 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3619) Synthase_beta PF11421.8 KFY03684.1 - 1.6 9.5 7.0 0.3 11.8 0.4 2.8 2 0 0 2 2 2 0 ATP synthase F1 beta subunit EamA PF00892.20 KFY03685.1 - 4.2e-07 30.2 26.0 2.5e-05 24.4 0.7 2.5 3 0 0 3 3 3 2 EamA-like transporter family CSG2 PF16965.5 KFY03685.1 - 0.00018 20.6 6.6 0.0011 18.0 6.6 2.4 1 1 0 1 1 1 1 Ceramide synthase regulator SCP2 PF02036.17 KFY03686.1 - 4.3e-23 81.7 1.2 5.8e-23 81.3 1.2 1.2 1 0 0 1 1 1 1 SCP-2 sterol transfer family Alkyl_sulf_C PF14864.6 KFY03686.1 - 8.8e-07 29.2 0.2 1.4e-06 28.6 0.2 1.2 1 0 0 1 1 1 1 Alkyl sulfatase C-terminal SCP2_2 PF13530.6 KFY03686.1 - 0.12 12.8 0.0 0.2 12.1 0.0 1.3 1 0 0 1 1 1 0 Sterol carrier protein domain ADH_zinc_N PF00107.26 KFY03692.1 - 7.9e-25 87.3 0.2 1.7e-24 86.3 0.2 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 KFY03692.1 - 1.8e-09 37.4 0.2 4.1e-09 36.2 0.2 1.6 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus AlaDh_PNT_C PF01262.21 KFY03692.1 - 1.2e-05 24.7 1.3 2.1e-05 23.9 1.3 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain ADH_zinc_N_2 PF13602.6 KFY03692.1 - 5.8e-05 24.2 0.0 0.00023 22.2 0.0 2.0 1 1 0 1 1 1 1 Zinc-binding dehydrogenase UDPG_MGDP_dh_N PF03721.14 KFY03692.1 - 0.0024 17.5 0.0 0.0056 16.3 0.0 1.6 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Methyltransf_25 PF13649.6 KFY03692.1 - 0.011 16.4 0.4 0.033 14.9 0.1 2.0 2 0 0 2 2 2 0 Methyltransferase domain 2-Hacid_dh_C PF02826.19 KFY03692.1 - 0.049 13.0 0.5 0.27 10.6 0.0 2.2 2 1 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain FtsJ PF01728.19 KFY03692.1 - 0.088 12.9 0.1 0.15 12.1 0.1 1.4 1 1 0 1 1 1 0 FtsJ-like methyltransferase DUF4045 PF13254.6 KFY03692.1 - 7.7 6.0 24.2 13 5.3 24.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) F-box-like PF12937.7 KFY03693.1 - 0.0012 18.7 1.4 0.0028 17.5 0.2 2.2 2 0 0 2 2 2 1 F-box-like Peptidase_A4 PF01828.17 KFY03694.1 - 2.1e-50 171.1 11.6 2.1e-50 171.1 11.6 1.6 2 0 0 2 2 2 1 Peptidase A4 family Abhydrolase_1 PF00561.20 KFY03694.1 - 6.5e-17 62.0 0.0 1.2e-16 61.1 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold EHN PF06441.12 KFY03694.1 - 4.7e-16 59.1 0.2 7.4e-14 52.0 0.1 2.7 1 1 1 2 2 2 2 Epoxide hydrolase N terminus Abhydrolase_6 PF12697.7 KFY03694.1 - 0.00024 21.8 2.0 0.00049 20.8 0.1 2.2 2 0 0 2 2 2 1 Alpha/beta hydrolase family bZIP_1 PF00170.21 KFY03694.1 - 0.0056 16.8 5.7 0.13 12.3 3.7 2.3 2 0 0 2 2 2 1 bZIP transcription factor Ecm33 PF12454.8 KFY03694.1 - 0.025 14.7 0.7 1.6 8.9 0.0 2.5 2 0 0 2 2 2 0 GPI-anchored cell wall organization protein Fungal_trans PF04082.18 KFY03695.1 - 8.1e-28 97.2 0.0 1.7e-27 96.1 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KFY03695.1 - 2.7e-11 43.4 10.0 6.1e-11 42.3 10.0 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Mtf2_C PF14061.6 KFY03695.1 - 0.013 15.6 0.1 0.027 14.6 0.1 1.5 1 0 0 1 1 1 0 Polycomb-like MTF2 factor 2 SLAC1 PF03595.17 KFY03696.1 - 3.4e-57 194.2 46.6 3.8e-57 194.0 46.6 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel Tom22 PF04281.13 KFY03696.1 - 0.38 10.5 1.8 0.97 9.2 1.8 1.6 1 0 0 1 1 1 0 Mitochondrial import receptor subunit Tom22 Ost4 PF10215.9 KFY03696.1 - 0.39 10.6 6.8 5.3 6.9 0.9 2.8 2 0 0 2 2 2 0 Oligosaccaryltransferase Zn_clus PF00172.18 KFY03697.1 - 1.3e-07 31.6 6.1 2.8e-07 30.6 6.1 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KFY03697.1 - 0.00088 18.4 0.1 0.0022 17.1 0.0 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain HSF_DNA-bind PF00447.17 KFY03697.1 - 0.15 12.7 0.5 30 5.3 0.1 2.5 2 0 0 2 2 2 0 HSF-type DNA-binding RPN5_C PF18098.1 KFY03697.1 - 0.91 9.7 3.7 0.71 10.0 0.2 2.5 3 0 0 3 3 3 0 26S proteasome regulatory subunit RPN5 C-terminal domain Sulfatase PF00884.23 KFY03698.1 - 9.6e-71 238.7 0.0 1.3e-70 238.3 0.0 1.2 1 0 0 1 1 1 1 Sulfatase DUF4976 PF16347.5 KFY03698.1 - 0.0068 16.6 0.0 0.017 15.4 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4976) Phosphodiest PF01663.22 KFY03698.1 - 0.17 11.4 0.1 1.1 8.8 0.0 2.1 3 0 0 3 3 3 0 Type I phosphodiesterase / nucleotide pyrophosphatase Sugar_tr PF00083.24 KFY03699.1 - 2.7e-103 346.3 16.8 3.2e-103 346.0 16.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KFY03699.1 - 1.9e-22 79.7 26.7 9e-21 74.2 11.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 KFY03699.1 - 0.00043 19.0 17.4 0.0073 14.9 1.4 3.2 2 1 1 3 3 3 2 MFS/sugar transport protein Ras PF00071.22 KFY03700.1 - 2.4e-40 137.8 0.0 3.6e-40 137.2 0.0 1.3 1 1 0 1 1 1 1 Ras family Roc PF08477.13 KFY03700.1 - 4.7e-29 101.0 0.0 6.3e-29 100.6 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFY03700.1 - 2.7e-10 40.0 0.0 3.9e-09 36.2 0.0 2.0 2 0 0 2 2 2 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 KFY03700.1 - 0.00046 20.2 0.0 0.00071 19.6 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 KFY03700.1 - 0.0012 18.2 0.0 0.0016 17.9 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 KFY03700.1 - 0.016 14.7 0.0 0.024 14.0 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit ABC_tran PF00005.27 KFY03700.1 - 0.019 15.5 0.0 0.033 14.7 0.0 1.4 1 0 0 1 1 1 0 ABC transporter GTP_EFTU PF00009.27 KFY03700.1 - 0.022 14.3 0.0 0.11 12.1 0.0 2.0 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain AAA_16 PF13191.6 KFY03700.1 - 0.029 14.8 1.0 0.23 11.8 1.0 2.2 1 1 0 1 1 1 0 AAA ATPase domain NACHT PF05729.12 KFY03700.1 - 0.038 13.9 0.0 0.083 12.8 0.0 1.5 2 0 0 2 2 2 0 NACHT domain AAA_29 PF13555.6 KFY03700.1 - 0.042 13.6 0.1 0.16 11.7 0.0 2.0 2 0 0 2 2 2 0 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 KFY03700.1 - 0.071 13.0 0.0 0.12 12.2 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase PduV-EutP PF10662.9 KFY03700.1 - 0.098 12.4 0.0 1.4 8.7 0.0 2.1 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_22 PF13401.6 KFY03700.1 - 0.12 12.7 0.0 0.21 11.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain ATPase_2 PF01637.18 KFY03700.1 - 0.14 12.0 0.0 0.2 11.6 0.0 1.2 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_7 PF12775.7 KFY03700.1 - 0.29 10.6 0.0 0.48 9.9 0.0 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region adh_short PF00106.25 KFY03701.1 - 3.2e-33 114.8 0.1 3.8e-33 114.6 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KFY03701.1 - 1.7e-28 99.8 0.1 2e-28 99.5 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KFY03701.1 - 2e-09 37.6 0.1 5.5e-09 36.2 0.1 1.8 1 1 0 1 1 1 1 KR domain Glyco_hydro_10 PF00331.20 KFY03702.1 - 2.3e-93 312.8 5.1 2.9e-93 312.5 5.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 Sulfate_transp PF00916.20 KFY03703.1 - 6.2e-67 226.0 13.3 9e-67 225.5 13.3 1.2 1 0 0 1 1 1 1 Sulfate permease family cNMP_binding PF00027.29 KFY03703.1 - 2.7e-16 59.4 0.0 5.1e-16 58.5 0.0 1.5 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain STAS PF01740.21 KFY03703.1 - 2.9e-09 36.6 0.0 5e-09 35.8 0.0 1.3 1 0 0 1 1 1 1 STAS domain MFS_MOT1 PF16983.5 KFY03703.1 - 0.14 12.6 15.4 3 8.3 4.5 3.5 3 0 0 3 3 3 0 Molybdate transporter of MFS superfamily DUF2613 PF11021.8 KFY03703.1 - 1.2 9.3 5.3 0.42 10.8 0.6 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2613) DUF3180 PF11377.8 KFY03703.1 - 2.3 8.4 10.0 0.5 10.5 5.8 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3180) Rer1 PF03248.13 KFY03703.1 - 3.6 7.3 7.3 7.7 6.2 7.3 1.5 1 0 0 1 1 1 0 Rer1 family Sld5 PF05916.11 KFY03704.1 - 1.3e-11 44.9 0.0 2.2e-11 44.2 0.0 1.4 1 0 0 1 1 1 1 GINS complex protein HMG_box PF00505.19 KFY03705.1 - 1e-10 41.8 0.1 1e-10 41.8 0.1 2.0 2 0 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KFY03705.1 - 0.0002 21.9 1.5 0.00028 21.4 0.2 2.0 2 0 0 2 2 2 1 HMG-box domain Glyco_transf_41 PF13844.6 KFY03707.1 - 2.3e-99 333.0 0.0 3.8e-52 177.3 0.0 3.1 3 0 0 3 3 3 2 Glycosyl transferase family 41 TPR_1 PF00515.28 KFY03707.1 - 1.2e-17 62.9 7.6 0.00013 21.7 0.0 5.7 6 0 0 6 6 5 4 Tetratricopeptide repeat TPR_2 PF07719.17 KFY03707.1 - 5.8e-15 54.1 10.5 0.006 16.6 0.0 6.2 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_11 PF13414.6 KFY03707.1 - 3.7e-13 48.9 12.5 0.0011 18.5 0.4 6.3 3 2 3 6 6 6 3 TPR repeat TPR_10 PF13374.6 KFY03707.1 - 7.3e-12 44.8 8.0 0.019 14.8 0.2 5.1 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_8 PF13181.6 KFY03707.1 - 2.3e-11 42.9 6.3 0.00076 19.5 0.2 5.1 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_12 PF13424.6 KFY03707.1 - 9.2e-10 38.7 10.0 0.00034 20.9 1.8 4.6 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_7 PF13176.6 KFY03707.1 - 1.6e-09 37.1 3.5 0.0021 18.0 0.0 4.8 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.6 KFY03707.1 - 3.7e-09 36.9 5.2 0.00025 21.5 1.0 3.5 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_17 PF13431.6 KFY03707.1 - 9.3e-08 31.9 7.3 0.21 12.1 0.4 5.1 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_16 PF13432.6 KFY03707.1 - 4.8e-07 30.3 5.7 0.00037 21.1 0.2 4.2 3 1 2 5 5 5 4 Tetratricopeptide repeat TPR_14 PF13428.6 KFY03707.1 - 8.8e-07 29.2 7.5 0.11 13.4 0.0 5.9 4 2 2 6 6 5 2 Tetratricopeptide repeat ANAPC3 PF12895.7 KFY03707.1 - 0.0014 18.8 0.3 0.058 13.6 0.2 2.7 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_15 PF13429.6 KFY03707.1 - 0.0014 17.9 0.1 0.048 12.9 0.0 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat BTAD PF03704.17 KFY03707.1 - 0.0039 17.6 1.7 0.11 13.0 0.0 2.8 3 0 0 3 3 2 1 Bacterial transcriptional activator domain TPR_9 PF13371.6 KFY03707.1 - 0.011 15.9 3.4 0.18 12.0 0.1 3.5 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.6 KFY03707.1 - 0.47 11.2 1.9 31 5.5 0.0 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat Ribosomal_L11_N PF03946.14 KFY03708.1 - 1.4e-24 85.7 0.2 2.4e-24 84.9 0.2 1.4 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.19 KFY03708.1 - 1.1e-16 61.0 0.3 1.9e-16 60.3 0.3 1.4 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain IF2_N PF04760.15 KFY03708.1 - 0.0042 16.9 0.3 0.14 11.9 0.0 2.5 1 1 1 2 2 2 2 Translation initiation factor IF-2, N-terminal region ROS_MUCR PF05443.11 KFY03708.1 - 0.089 12.8 0.1 0.12 12.4 0.1 1.2 1 0 0 1 1 1 0 ROS/MUCR transcriptional regulator protein Fibrillarin PF01269.17 KFY03709.1 - 3e-104 347.1 0.0 3.6e-104 346.8 0.0 1.0 1 0 0 1 1 1 1 Fibrillarin GCD14 PF08704.10 KFY03709.1 - 1.8e-05 24.5 0.0 2.8e-05 23.9 0.0 1.2 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit PCMT PF01135.19 KFY03709.1 - 0.012 15.4 0.1 0.018 14.8 0.1 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltr_RsmB-F PF01189.17 KFY03709.1 - 0.026 14.2 0.0 0.043 13.5 0.0 1.3 1 0 0 1 1 1 0 16S rRNA methyltransferase RsmB/F FtsJ PF01728.19 KFY03709.1 - 0.15 12.1 0.0 0.2 11.8 0.0 1.3 1 0 0 1 1 1 0 FtsJ-like methyltransferase TPR_1 PF00515.28 KFY03711.1 - 1.1e-14 53.6 3.5 9.2e-06 25.3 0.0 4.5 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.17 KFY03711.1 - 4.6e-13 48.2 2.6 0.00017 21.5 0.0 4.5 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_8 PF13181.6 KFY03711.1 - 1.3e-07 31.3 0.7 0.0025 17.9 0.0 4.0 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.6 KFY03711.1 - 1.5e-07 31.6 0.0 0.00035 20.8 0.0 3.3 2 1 1 3 3 3 2 Tetratricopeptide repeat PB1 PF00564.24 KFY03711.1 - 6.8e-07 29.1 0.4 1.2e-06 28.3 0.4 1.5 1 0 0 1 1 1 1 PB1 domain TPR_7 PF13176.6 KFY03711.1 - 1.8e-05 24.4 0.2 0.0013 18.6 0.0 3.1 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.6 KFY03711.1 - 2.4e-05 23.9 1.0 0.0011 18.6 0.1 3.5 2 1 1 3 3 3 1 TPR repeat TPR_6 PF13174.6 KFY03711.1 - 4.7e-05 23.8 0.1 13 6.7 0.0 4.6 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_16 PF13432.6 KFY03711.1 - 0.0054 17.4 0.6 0.17 12.6 0.1 2.5 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_9 PF13371.6 KFY03711.1 - 0.0066 16.6 0.0 3.1 8.0 0.0 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 KFY03711.1 - 0.06 14.2 0.0 1.9 9.5 0.0 2.9 3 0 0 3 3 2 0 Tetratricopeptide repeat TPR_17 PF13431.6 KFY03711.1 - 0.11 12.9 0.0 3.7 8.1 0.0 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat NOA36 PF06524.12 KFY03711.1 - 7 5.9 6.1 12 5.1 6.1 1.3 1 0 0 1 1 1 0 NOA36 protein Ribosomal_L13 PF00572.18 KFY03712.1 - 1.3e-41 141.7 0.0 2.8e-41 140.7 0.0 1.4 2 0 0 2 2 2 1 Ribosomal protein L13 Uricase PF01014.18 KFY03713.1 - 3.7e-78 260.1 1.8 9.4e-41 139.1 0.8 2.0 2 0 0 2 2 2 2 Uricase Mob_Pre PF01076.19 KFY03713.1 - 0.054 13.3 0.0 0.09 12.6 0.0 1.3 1 0 0 1 1 1 0 Plasmid recombination enzyme RICTOR_N PF14664.6 KFY03714.1 - 2.1e-136 454.8 0.8 2.1e-136 454.8 0.8 2.3 3 0 0 3 3 3 1 Rapamycin-insensitive companion of mTOR, N-term RasGEF_N_2 PF14663.6 KFY03714.1 - 5e-38 129.8 0.8 2e-35 121.5 0.0 3.8 4 0 0 4 4 4 1 Rapamycin-insensitive companion of mTOR RasGEF_N domain RICTOR_M PF14666.6 KFY03714.1 - 7.1e-36 122.1 1.2 4.6e-33 113.1 0.1 4.5 3 1 2 5 5 5 1 Rapamycin-insensitive companion of mTOR, middle domain RICTOR_V PF14668.6 KFY03714.1 - 7.5e-32 109.4 0.9 3.4e-29 100.9 0.1 4.6 5 0 0 5 5 5 1 Rapamycin-insensitive companion of mTOR, domain 5 HR1 PF02185.16 KFY03714.1 - 1.4e-13 50.8 11.7 1.4e-13 50.8 11.7 2.0 2 0 0 2 2 2 1 Hr1 repeat Proteasom_PSMB PF10508.9 KFY03714.1 - 2.9e-06 26.1 1.7 0.043 12.3 0.0 4.9 4 1 1 5 5 5 2 Proteasome non-ATPase 26S subunit Uds1 PF15456.6 KFY03714.1 - 0.0059 16.8 2.4 0.021 15.0 2.4 2.0 1 0 0 1 1 1 1 Up-regulated During Septation HOOK PF05622.12 KFY03714.1 - 0.034 12.3 6.1 0.064 11.4 6.1 1.3 1 0 0 1 1 1 0 HOOK protein FAM76 PF16046.5 KFY03714.1 - 0.073 12.4 3.7 0.13 11.6 3.7 1.3 1 0 0 1 1 1 0 FAM76 protein DUF4611 PF15387.6 KFY03714.1 - 0.13 12.5 1.2 19 5.6 0.1 3.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) DUF2443 PF10398.9 KFY03714.1 - 0.18 11.9 0.7 0.52 10.4 0.7 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2443) Cep57_MT_bd PF06657.13 KFY03714.1 - 7.9 7.0 7.4 11 6.6 0.1 2.8 2 1 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 DUF2203 PF09969.9 KFY03714.1 - 8.2 7.2 8.5 2.6 8.8 4.9 2.0 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) PCI PF01399.27 KFY03715.1 - 1.2e-13 51.4 0.1 1.7e-13 51.0 0.1 1.2 1 0 0 1 1 1 1 PCI domain HTH_54 PF18607.1 KFY03715.1 - 0.068 13.2 0.1 0.14 12.3 0.1 1.5 1 0 0 1 1 1 0 ParA helix turn helix domain MutS_V PF00488.21 KFY03717.1 - 9.5e-83 276.9 0.1 1.8e-82 276.0 0.1 1.5 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 KFY03717.1 - 2.5e-35 122.4 1.1 7.2e-35 121.0 1.1 1.8 1 0 0 1 1 1 1 MutS domain III MutS_II PF05188.17 KFY03717.1 - 2.4e-20 73.2 0.0 7.2e-20 71.7 0.0 1.9 1 0 0 1 1 1 1 MutS domain II MutS_I PF01624.20 KFY03717.1 - 9.9e-20 70.9 0.3 5.2e-19 68.6 0.0 2.3 3 0 0 3 3 3 1 MutS domain I MutS_IV PF05190.18 KFY03717.1 - 3.9e-17 62.4 2.0 1.4e-16 60.6 2.0 2.1 1 0 0 1 1 1 1 MutS family domain IV TetR_C_7 PF14246.6 KFY03717.1 - 0.08 13.0 0.0 0.29 11.1 0.0 2.0 1 0 0 1 1 1 0 AefR-like transcriptional repressor, C-terminal domain Peptidase_M16 PF00675.20 KFY03717.1 - 0.082 12.9 0.2 0.35 10.8 0.1 2.1 2 0 0 2 2 2 0 Insulinase (Peptidase family M16) SYS1 PF09801.9 KFY03719.1 - 8e-51 172.0 12.0 9.1e-51 171.8 12.0 1.0 1 0 0 1 1 1 1 Integral membrane protein S linking to the trans Golgi network DUF2070 PF09843.9 KFY03719.1 - 1.4 7.1 10.3 1.7 6.8 10.3 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) DUF3792 PF12670.7 KFY03719.1 - 2.2 8.4 13.0 1.1 9.5 0.1 2.8 1 1 1 2 2 2 0 Protein of unknown function (DUF3792) COX6B PF02297.17 KFY03720.1 - 1.8e-25 89.0 5.2 2.3e-25 88.6 5.2 1.1 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb Pet191_N PF10203.9 KFY03720.1 - 0.041 14.2 2.6 0.48 10.8 2.7 2.0 1 1 1 2 2 2 0 Cytochrome c oxidase assembly protein PET191 AA_permease_2 PF13520.6 KFY03722.1 - 4.3e-40 137.8 21.9 5.1e-40 137.6 21.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KFY03722.1 - 1.8e-13 49.9 15.4 2.2e-13 49.6 15.4 1.1 1 0 0 1 1 1 1 Amino acid permease DUF1980 PF09323.10 KFY03722.1 - 0.015 15.2 1.4 0.19 11.6 0.7 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1980) DUF2530 PF10745.9 KFY03722.1 - 4.2 7.7 7.6 22 5.4 0.0 3.7 4 0 0 4 4 4 0 Protein of unknown function (DUF2530) Na_Ca_ex PF01699.24 KFY03723.1 - 8.6e-33 113.4 40.5 2e-18 66.8 16.7 2.0 2 0 0 2 2 2 2 Sodium/calcium exchanger protein CVNH PF08881.10 KFY03724.1 - 7e-17 62.0 2.0 1.3e-09 38.6 0.1 2.0 1 1 1 2 2 2 2 CVNH domain Sedlin_N PF04628.13 KFY03726.1 - 4.9e-38 130.2 0.0 7.8e-38 129.6 0.0 1.2 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region Thiamine_BP PF01910.17 KFY03726.1 - 2.1e-30 104.5 0.1 3.3e-30 103.8 0.1 1.3 1 0 0 1 1 1 1 Thiamine-binding protein L31 PF09784.9 KFY03727.1 - 3e-44 149.6 2.5 3.3e-44 149.5 2.5 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L31 YpzI PF14140.6 KFY03727.1 - 0.046 13.5 2.3 0.35 10.7 0.1 2.2 2 0 0 2 2 2 0 YpzI-like protein RRM_1 PF00076.22 KFY03728.1 - 1.5e-14 53.5 0.0 2.2e-14 53.0 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SRP_TPR_like PF17004.5 KFY03729.1 - 3e-32 111.1 2.1 9e-31 106.3 1.3 2.4 2 0 0 2 2 2 1 Putative TPR-like repeat SRP72 PF08492.12 KFY03729.1 - 3e-13 50.0 6.8 3e-13 50.0 6.8 2.4 2 0 0 2 2 1 1 SRP72 RNA-binding domain TPR_19 PF14559.6 KFY03729.1 - 5.3e-05 23.6 10.9 0.16 12.5 1.4 5.1 4 1 1 5 5 5 2 Tetratricopeptide repeat Nup88 PF10168.9 KFY03729.1 - 7.3e-05 20.8 3.6 0.026 12.3 0.0 2.2 2 0 0 2 2 2 2 Nuclear pore component ANAPC3 PF12895.7 KFY03729.1 - 0.0004 20.6 1.5 0.067 13.4 0.2 3.3 4 0 0 4 4 3 1 Anaphase-promoting complex, cyclosome, subunit 3 GGA_N-GAT PF18308.1 KFY03729.1 - 0.00044 19.8 2.7 0.32 10.6 0.1 3.5 3 0 0 3 3 3 2 GGA N-GAT domain TPR_2 PF07719.17 KFY03729.1 - 0.011 15.8 1.7 16 5.9 0.0 4.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.6 KFY03729.1 - 0.035 14.3 0.1 5.4 7.5 0.0 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat SH3BP5 PF05276.14 KFY03729.1 - 0.068 13.0 1.3 0.19 11.5 0.3 2.0 2 0 0 2 2 2 0 SH3 domain-binding protein 5 (SH3BP5) Seryl_tRNA_N PF02403.22 KFY03729.1 - 0.073 13.3 4.3 0.61 10.4 4.3 2.6 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain CNP1 PF08750.11 KFY03729.1 - 0.11 12.4 0.0 0.24 11.4 0.0 1.5 1 0 0 1 1 1 0 CNP1-like family BTAD PF03704.17 KFY03729.1 - 0.15 12.5 5.8 0.038 14.4 0.7 2.7 3 0 0 3 3 2 0 Bacterial transcriptional activator domain THOC7 PF05615.13 KFY03729.1 - 0.25 11.6 3.0 0.94 9.8 3.0 1.9 1 0 0 1 1 1 0 Tho complex subunit 7 CTK3_C PF12350.8 KFY03729.1 - 0.34 11.1 4.0 14 5.9 4.0 2.8 1 1 0 1 1 1 0 CTD kinase subunit gamma CTK3 C-terminus Hormone_1 PF00103.20 KFY03729.1 - 0.94 9.2 2.3 18 5.0 0.6 2.5 2 0 0 2 2 2 0 Somatotropin hormone family TPR_12 PF13424.6 KFY03729.1 - 1.3 9.3 4.7 16 5.9 0.1 3.9 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_14 PF13428.6 KFY03729.1 - 3.8 8.6 12.7 1.1e+02 4.0 1.3 6.4 4 2 2 6 6 6 0 Tetratricopeptide repeat Ubiq_cyt_C_chap PF03981.12 KFY03730.1 - 3e-38 131.1 0.3 4.9e-38 130.4 0.3 1.3 1 0 0 1 1 1 1 Ubiquinol-cytochrome C chaperone Epimerase PF01370.21 KFY03732.1 - 3.8e-14 52.7 0.0 8.9e-14 51.5 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 KFY03732.1 - 2.9e-09 36.5 0.0 5.3e-08 32.3 0.0 2.0 1 1 0 1 1 1 1 Male sterility protein 3Beta_HSD PF01073.19 KFY03732.1 - 8e-08 31.6 0.0 2.1e-07 30.3 0.0 1.6 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 KFY03732.1 - 0.0069 16.3 0.0 0.015 15.2 0.0 1.7 1 1 0 1 1 1 1 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 KFY03732.1 - 0.011 15.2 0.0 0.015 14.7 0.0 1.3 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase KR PF08659.10 KFY03732.1 - 0.039 13.8 0.0 0.12 12.3 0.0 1.7 1 1 0 1 1 1 0 KR domain adh_short PF00106.25 KFY03732.1 - 0.13 11.7 0.0 0.23 10.9 0.0 1.4 1 0 0 1 1 1 0 short chain dehydrogenase DEAD PF00270.29 KFY03733.1 - 4.9e-41 140.4 1.6 7.6e-41 139.8 1.6 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KFY03733.1 - 2.8e-32 111.3 0.0 1.9e-30 105.5 0.0 2.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 KFY03733.1 - 1.1e-07 32.1 0.0 2e-07 31.2 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Peptidase_M19 PF01244.21 KFY03733.1 - 0.009 15.2 0.1 0.018 14.2 0.1 1.4 1 0 0 1 1 1 1 Membrane dipeptidase (Peptidase family M19) SH3_9 PF14604.6 KFY03736.1 - 1.6e-10 40.6 0.3 5.2e-10 39.0 0.4 1.8 2 0 0 2 2 2 1 Variant SH3 domain SH3_1 PF00018.28 KFY03736.1 - 9.3e-10 38.0 0.2 2.3e-09 36.7 0.2 1.7 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 KFY03736.1 - 2.8e-09 36.5 0.1 5.7e-09 35.5 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain DNA_pol_phi PF04931.13 KFY03736.1 - 8.8 4.3 7.6 16 3.4 7.6 1.3 1 0 0 1 1 1 0 DNA polymerase phi RPAP2_Rtr1 PF04181.13 KFY03737.1 - 1.7e-19 69.9 0.0 2.8e-19 69.2 0.0 1.3 1 0 0 1 1 1 1 Rtr1/RPAP2 family Ribosomal_S17e PF00833.18 KFY03738.1 - 2e-60 202.0 0.6 2.4e-60 201.8 0.6 1.0 1 0 0 1 1 1 1 Ribosomal S17 Mit_ribos_Mrp51 PF11709.8 KFY03739.1 - 7.2e-128 427.2 0.1 9.4e-128 426.8 0.1 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal protein subunit Inv-AAD PF18785.1 KFY03740.1 - 5e-64 214.0 0.3 5.8e-64 213.7 0.3 1.0 1 0 0 1 1 1 1 Invertebrate-AID/APOBEC-deaminase dCMP_cyt_deam_1 PF00383.23 KFY03740.1 - 3.6e-14 52.5 0.1 6.1e-14 51.7 0.1 1.2 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region APOBEC_N PF08210.11 KFY03740.1 - 0.00015 21.7 0.2 0.00039 20.4 0.2 1.6 1 1 0 1 1 1 1 APOBEC-like N-terminal domain NAD1 PF18778.1 KFY03740.1 - 0.097 12.8 0.1 0.15 12.1 0.1 1.3 1 1 0 1 1 1 0 Novel AID APOBEC clade 1 CD99L2 PF12301.8 KFY03742.1 - 0.029 14.7 0.3 0.029 14.7 0.3 2.0 2 0 0 2 2 2 0 CD99 antigen like protein 2 Chitin_synth_1 PF01644.17 KFY03743.1 - 1.6e-79 265.6 0.2 2.6e-79 264.9 0.2 1.3 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.11 KFY03743.1 - 1.5e-27 95.3 0.1 3.1e-27 94.3 0.1 1.6 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.15 KFY03743.1 - 2.7e-25 89.0 3.9 2.3e-21 76.0 0.0 2.4 2 0 0 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.6 KFY03743.1 - 2.1e-08 34.3 2.8 7.6e-08 32.5 2.8 2.1 1 1 0 1 1 1 1 Glycosyl transferase family group 2 DUF3995 PF13160.6 KFY03743.1 - 0.022 15.1 0.1 0.056 13.8 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3995) DUF1993 PF09351.10 KFY03744.1 - 6.5e-54 182.4 0.0 7.2e-54 182.3 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1993) Pyr_redox_2 PF07992.14 KFY03745.1 - 8.3e-33 113.9 0.2 1e-32 113.6 0.2 1.0 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KFY03745.1 - 1.9e-07 31.5 0.4 1.5e-05 25.5 0.2 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KFY03745.1 - 0.001 19.1 0.5 2.9 7.9 0.0 3.9 5 0 0 5 5 5 1 FAD-NAD(P)-binding Phage_spike PF18715.1 KFY03745.1 - 0.085 12.9 0.0 11 6.1 0.0 2.5 2 0 0 2 2 2 0 Phage spike trimer DAO PF01266.24 KFY03745.1 - 0.13 11.8 3.0 4 6.9 0.1 2.9 2 1 1 3 3 3 0 FAD dependent oxidoreductase Fungal_trans_2 PF11951.8 KFY03746.1 - 2.6e-46 158.2 5.8 3.1e-46 157.9 5.8 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KFY03746.1 - 7.4e-10 38.8 6.5 1.5e-09 37.8 6.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DNApol3-delta_C PF09115.10 KFY03746.1 - 0.057 13.9 1.0 0.11 13.1 0.2 1.8 2 0 0 2 2 2 0 DNA polymerase III, delta subunit, C terminal GMC_oxred_N PF00732.19 KFY03747.1 - 1.4e-33 116.5 0.0 5.7e-28 98.1 0.0 2.7 2 1 0 2 2 2 2 GMC oxidoreductase GMC_oxred_C PF05199.13 KFY03747.1 - 7.1e-29 101.2 0.0 1.1e-28 100.5 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.6 KFY03747.1 - 4.5e-05 23.6 1.2 0.00014 22.0 1.2 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 KFY03747.1 - 0.00087 18.5 0.1 0.0016 17.6 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain Lycopene_cycl PF05834.12 KFY03747.1 - 0.0031 16.6 0.0 0.0043 16.1 0.0 1.1 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_2 PF07992.14 KFY03747.1 - 0.03 13.6 0.0 0.055 12.7 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.16 KFY03747.1 - 0.034 13.8 1.1 0.069 12.8 0.7 1.7 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA DAO PF01266.24 KFY03747.1 - 0.06 12.9 0.0 0.58 9.7 0.1 2.4 3 0 0 3 3 3 0 FAD dependent oxidoreductase HI0933_like PF03486.14 KFY03747.1 - 0.1 11.3 0.5 0.15 10.7 0.5 1.2 1 0 0 1 1 1 0 HI0933-like protein Pyr_redox_3 PF13738.6 KFY03747.1 - 0.18 11.0 0.1 7 5.8 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Sugar_tr PF00083.24 KFY03748.1 - 1.3e-119 400.1 21.1 1.5e-119 399.9 21.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KFY03748.1 - 3.6e-27 95.2 22.2 3.3e-20 72.3 3.2 2.0 2 0 0 2 2 2 2 Major Facilitator Superfamily ABC2_membrane PF01061.24 KFY03749.1 - 2.8e-82 275.2 58.0 7.8e-43 146.3 31.3 3.1 3 0 0 3 3 2 2 ABC-2 type transporter ABC_tran PF00005.27 KFY03749.1 - 2.9e-38 131.5 0.1 4.1e-19 69.5 0.0 2.9 3 0 0 3 3 2 2 ABC transporter PDR_CDR PF06422.12 KFY03749.1 - 1.6e-26 92.0 11.0 9.1e-25 86.4 0.0 3.1 3 0 0 3 3 2 2 CDR ABC transporter ABC_trans_N PF14510.6 KFY03749.1 - 2e-12 47.5 0.2 4.9e-12 46.3 0.2 1.7 1 0 0 1 1 1 1 ABC-transporter N-terminal AAA_33 PF13671.6 KFY03749.1 - 1.2e-06 28.8 0.0 0.00033 20.8 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 KFY03749.1 - 1.6e-06 28.7 0.0 0.00022 21.8 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_21 PF13304.6 KFY03749.1 - 3.4e-06 27.1 0.0 0.0065 16.3 0.0 2.5 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 KFY03749.1 - 4.3e-06 27.2 0.0 0.0055 17.1 0.1 2.5 2 0 0 2 2 2 2 AAA ATPase domain RsgA_GTPase PF03193.16 KFY03749.1 - 2.1e-05 24.5 0.1 0.0006 19.8 0.1 2.4 2 0 0 2 2 2 1 RsgA GTPase MMR_HSR1 PF01926.23 KFY03749.1 - 0.00026 21.1 0.1 0.091 12.8 0.0 2.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_22 PF13401.6 KFY03749.1 - 0.00051 20.3 0.0 0.16 12.2 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.6 KFY03749.1 - 0.00072 19.8 0.4 0.0044 17.3 0.1 2.4 3 0 0 3 3 2 1 AAA domain AAA_29 PF13555.6 KFY03749.1 - 0.00083 19.1 1.9 0.44 10.3 0.1 3.0 3 0 0 3 3 3 2 P-loop containing region of AAA domain AAA_25 PF13481.6 KFY03749.1 - 0.0023 17.5 0.4 0.22 11.1 0.3 2.5 2 0 0 2 2 2 1 AAA domain cobW PF02492.19 KFY03749.1 - 0.0024 17.5 0.1 0.035 13.7 0.0 2.4 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain NACHT PF05729.12 KFY03749.1 - 0.0032 17.4 0.6 0.6 10.0 0.5 2.4 2 0 0 2 2 2 1 NACHT domain AAA_24 PF13479.6 KFY03749.1 - 0.0038 17.0 0.1 0.31 10.8 0.0 3.0 3 0 0 3 3 3 1 AAA domain SMC_N PF02463.19 KFY03749.1 - 0.0053 16.2 0.4 0.04 13.3 0.0 2.5 4 0 0 4 4 3 1 RecF/RecN/SMC N terminal domain FtsK_SpoIIIE PF01580.18 KFY03749.1 - 0.014 14.7 0.4 6.8 6.0 0.0 2.5 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA PF00004.29 KFY03749.1 - 0.027 14.9 0.4 13 6.2 0.0 2.8 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 KFY03749.1 - 0.068 13.6 0.0 11 6.4 0.1 3.2 3 0 0 3 3 3 0 RNA helicase AAA_17 PF13207.6 KFY03749.1 - 0.076 13.4 1.6 2.4 8.6 0.0 3.0 3 0 0 3 3 3 0 AAA domain Septin PF00735.18 KFY03749.1 - 0.094 12.0 0.9 0.54 9.5 0.1 2.2 2 0 0 2 2 2 0 Septin T2SSE PF00437.20 KFY03749.1 - 0.13 11.3 0.1 3.9 6.5 0.1 2.2 2 0 0 2 2 2 0 Type II/IV secretion system protein NB-ARC PF00931.22 KFY03749.1 - 0.18 11.0 1.5 4.4 6.4 0.4 2.3 2 0 0 2 2 2 0 NB-ARC domain ATG19_autophagy PF12744.7 KFY03749.1 - 0.25 10.5 3.2 0.16 11.2 0.2 2.0 2 0 0 2 2 2 0 Autophagy protein Atg19, Atg8-binding TsaE PF02367.17 KFY03749.1 - 0.41 10.7 3.0 1 9.3 0.4 2.7 3 0 0 3 3 3 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_30 PF13604.6 KFY03749.1 - 0.44 10.2 4.8 1.8 8.2 0.4 2.9 3 0 0 3 3 3 0 AAA domain SecE PF00584.20 KFY03749.1 - 8.4 6.4 10.6 5.8 6.9 0.1 3.9 3 0 0 3 3 3 0 SecE/Sec61-gamma subunits of protein translocation complex Glyco_hydro_36 PF17167.4 KFY03750.1 - 3.2e-63 213.9 0.1 7.7e-63 212.6 0.1 1.5 1 1 0 1 1 1 1 Glycosyl hydrolase 36 superfamily, catalytic domain Glyco_transf_36 PF06165.11 KFY03750.1 - 4.2e-27 95.1 0.0 7.1e-27 94.4 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase family 36 Bac_rhamnosid6H PF17389.2 KFY03750.1 - 0.0012 18.2 0.2 0.0025 17.1 0.1 1.5 2 0 0 2 2 2 1 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain Glyco_hydro_65C PF03633.15 KFY03750.1 - 0.0023 17.8 0.1 0.0073 16.2 0.0 1.9 2 0 0 2 2 2 1 Glycosyl hydrolase family 65, C-terminal domain GDE_C PF06202.14 KFY03750.1 - 0.0045 16.0 0.0 0.011 14.8 0.0 1.5 1 1 0 1 1 1 1 Amylo-alpha-1,6-glucosidase AAA PF00004.29 KFY03751.1 - 2e-16 60.6 0.0 8.4e-16 58.6 0.0 2.1 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KFY03751.1 - 0.0014 18.9 0.7 0.019 15.2 0.1 2.7 1 1 1 2 2 2 1 AAA domain AAA_5 PF07728.14 KFY03751.1 - 0.0016 18.4 0.0 0.0038 17.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Macoilin PF09726.9 KFY03751.1 - 0.0034 16.0 23.6 0.0061 15.2 23.6 1.3 1 0 0 1 1 1 1 Macoilin family AAA_16 PF13191.6 KFY03751.1 - 0.038 14.4 0.9 0.25 11.7 0.9 2.3 1 1 0 1 1 1 0 AAA ATPase domain AAA_33 PF13671.6 KFY03751.1 - 0.063 13.4 0.1 0.21 11.7 0.1 1.9 1 1 0 1 1 1 0 AAA domain AAA_11 PF13086.6 KFY03751.1 - 0.12 12.1 0.0 0.12 12.1 0.0 3.6 3 2 0 3 3 3 0 AAA domain Hamartin PF04388.12 KFY03751.1 - 0.28 9.8 14.9 0.53 8.9 14.9 1.5 1 0 0 1 1 1 0 Hamartin protein SOBP PF15279.6 KFY03751.1 - 4 8.0 19.3 8.9 6.8 19.3 1.6 1 0 0 1 1 1 0 Sine oculis-binding protein 4PPT_N PF17837.1 KFY03754.1 - 0.067 13.3 0.1 0.27 11.4 0.0 1.9 2 0 0 2 2 2 0 4'-phosphopantetheinyl transferase N-terminal domain FTA2 PF13095.6 KFY03760.1 - 1e-08 35.1 0.0 5.8e-08 32.6 0.0 2.2 1 1 0 1 1 1 1 Kinetochore Sim4 complex subunit FTA2 Pkinase PF00069.25 KFY03760.1 - 0.0001 21.8 0.1 0.04 13.3 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain FTA2 PF13095.6 KFY03761.1 - 0.011 15.4 0.0 0.23 11.1 0.0 2.4 1 1 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 HALZ PF02183.18 KFY03764.1 - 0.013 15.7 0.4 0.025 14.8 0.4 1.5 1 0 0 1 1 1 0 Homeobox associated leucine zipper WD40 PF00400.32 KFY03766.1 - 1.9e-21 76.0 5.9 1.1e-06 29.3 0.1 7.5 7 0 0 7 7 7 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFY03766.1 - 7.3e-09 35.8 0.1 0.27 11.5 0.0 5.4 2 2 3 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 KFY03766.1 - 5.2e-06 26.3 1.7 31 4.7 0.0 6.7 7 0 0 7 7 7 0 WD40-like Beta Propeller Repeat Ge1_WD40 PF16529.5 KFY03766.1 - 0.0015 17.6 3.6 2.9 6.7 0.2 5.0 2 2 4 6 6 6 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Nbas_N PF15492.6 KFY03766.1 - 0.0074 15.6 0.7 0.8 9.0 0.0 3.5 4 0 0 4 4 4 1 Neuroblastoma-amplified sequence, N terminal Gmad1 PF10647.9 KFY03766.1 - 0.42 10.3 2.6 2.8 7.6 0.9 3.0 3 1 0 3 3 3 0 Lipoprotein LpqB beta-propeller domain Ribosomal_L18 PF17135.4 KFY03770.1 - 3.3e-67 225.5 1.0 3.7e-67 225.4 1.0 1.0 1 0 0 1 1 1 1 Ribosomal protein 60S L18 and 50S L18e Ribosomal_L27A PF00828.19 KFY03770.1 - 0.0044 17.7 1.5 0.0056 17.3 0.0 1.9 2 0 0 2 2 2 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A Mito_carr PF00153.27 KFY03771.1 - 2e-72 239.2 5.0 3.9e-24 84.4 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 KFY03771.1 - 0.00068 18.9 1.3 0.024 13.8 0.0 3.0 2 1 2 4 4 4 1 Gammaproteobacterial serine protease PT-VENN PF04829.13 KFY03771.1 - 3.9 7.6 4.4 15 5.8 0.1 2.9 3 0 0 3 3 3 0 Pre-toxin domain with VENN motif RRM_1 PF00076.22 KFY03773.1 - 4e-12 45.8 0.0 5.7e-12 45.3 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 KFY03773.1 - 0.00083 19.3 0.0 0.0012 18.8 0.0 1.3 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif SWIRM-assoc_2 PF16496.5 KFY03773.1 - 2.3 7.0 8.4 2.8 6.7 8.4 1.1 1 0 0 1 1 1 0 SWIRM-associated domain at the N-terminal CH PF00307.31 KFY03774.1 - 1.3e-73 244.2 0.1 4.5e-20 71.9 0.0 4.1 4 0 0 4 4 4 4 Calponin homology (CH) domain EF-hand_7 PF13499.6 KFY03774.1 - 2.3e-06 28.0 1.2 3.7e-05 24.1 0.1 3.0 3 0 0 3 3 3 1 EF-hand domain pair EF-hand_1 PF00036.32 KFY03774.1 - 0.00018 20.8 1.7 0.25 11.0 0.4 3.6 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.6 KFY03774.1 - 0.0024 17.7 3.6 0.076 13.0 0.1 3.4 3 0 0 3 3 3 1 EF-hand domain EF-hand_5 PF13202.6 KFY03774.1 - 0.18 11.4 3.2 0.79 9.3 0.4 2.9 2 0 0 2 2 2 0 EF hand DWNN PF08783.11 KFY03775.1 - 1.2e-31 108.8 0.1 2e-31 108.1 0.1 1.4 1 0 0 1 1 1 1 DWNN domain zf-CCHC_2 PF13696.6 KFY03775.1 - 1.2e-08 34.6 4.7 2.2e-08 33.8 4.7 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC PF00098.23 KFY03775.1 - 0.00038 20.4 1.0 0.00074 19.5 1.0 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-C3HC4_2 PF13923.6 KFY03775.1 - 0.0019 18.0 9.1 0.0019 18.0 9.1 1.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) U-box PF04564.15 KFY03775.1 - 0.0026 17.9 0.1 0.0074 16.4 0.1 1.8 1 0 0 1 1 1 1 U-box domain zf-Nse PF11789.8 KFY03775.1 - 0.031 14.1 4.8 0.072 12.9 4.8 1.6 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-DNL PF05180.12 KFY03775.1 - 0.038 13.9 0.1 0.1 12.6 0.1 1.7 1 0 0 1 1 1 0 DNL zinc finger DUF3332 PF11810.8 KFY03775.1 - 0.14 11.8 0.8 0.29 10.8 0.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3332) zf-RING_4 PF14570.6 KFY03775.1 - 0.15 11.9 5.8 0.32 10.8 5.8 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING_2 PF13639.6 KFY03775.1 - 0.21 12.0 6.8 0.44 10.9 6.8 1.6 1 0 0 1 1 1 0 Ring finger domain zf-C3HC4_4 PF15227.6 KFY03775.1 - 0.24 11.6 9.2 0.81 9.9 9.2 2.0 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.6 KFY03775.1 - 0.57 10.2 7.0 1.1 9.3 7.0 1.5 1 0 0 1 1 1 0 RING-type zinc-finger zf-C3HC4 PF00097.25 KFY03775.1 - 0.65 9.9 9.2 1.3 8.9 9.2 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 KFY03775.1 - 2.5 8.1 11.6 0.31 11.0 6.3 2.1 2 0 0 2 2 2 0 zinc-RING finger domain His_biosynth PF00977.21 KFY03776.1 - 6.3e-46 156.7 0.9 2.7e-45 154.6 0.9 2.0 1 1 0 1 1 1 1 Histidine biosynthesis protein GATase PF00117.28 KFY03776.1 - 8.2e-22 77.9 0.0 1.3e-21 77.2 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I SNO PF01174.19 KFY03776.1 - 2.9e-11 43.5 0.0 5.9e-11 42.6 0.0 1.5 1 0 0 1 1 1 1 SNO glutamine amidotransferase family GATase_3 PF07685.14 KFY03776.1 - 1.4e-07 31.3 0.0 2.4e-07 30.5 0.0 1.3 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain DJ-1_PfpI PF01965.24 KFY03776.1 - 0.013 15.3 0.2 0.1 12.4 0.0 2.3 2 0 0 2 2 2 0 DJ-1/PfpI family Peptidase_C26 PF07722.13 KFY03776.1 - 0.013 15.3 0.0 0.034 13.9 0.0 1.7 1 1 0 1 1 1 0 Peptidase C26 Peptidase_S51 PF03575.17 KFY03776.1 - 0.05 13.2 0.0 0.098 12.3 0.0 1.4 1 0 0 1 1 1 0 Peptidase family S51 dCMP_cyt_deam_1 PF00383.23 KFY03777.1 - 7.4e-29 99.6 1.0 1.2e-28 98.9 1.0 1.3 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 KFY03777.1 - 2.4e-11 43.5 0.1 4.7e-11 42.6 0.1 1.4 1 0 0 1 1 1 1 MafB19-like deaminase AAA_18 PF13238.6 KFY03777.1 - 0.00068 20.2 0.1 0.0024 18.4 0.1 1.9 1 1 0 1 1 1 1 AAA domain CoaE PF01121.20 KFY03777.1 - 0.0011 18.7 0.0 0.0018 18.0 0.0 1.3 1 0 0 1 1 1 1 Dephospho-CoA kinase ATG7_N PF16420.5 KFY03778.1 - 2.9e-109 365.3 0.0 3.8e-109 365.0 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-like modifier-activating enzyme ATG7 N-terminus ThiF PF00899.21 KFY03778.1 - 3.7e-43 147.6 0.0 5.3e-43 147.1 0.0 1.2 1 0 0 1 1 1 1 ThiF family Shikimate_DH PF01488.20 KFY03778.1 - 0.01 15.9 0.1 0.086 12.9 0.0 2.3 1 1 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase 2-Hacid_dh_C PF02826.19 KFY03778.1 - 0.12 11.8 0.0 0.9 8.9 0.0 2.2 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain COPIIcoated_ERV PF07970.12 KFY03778.1 - 0.12 12.2 0.3 0.21 11.4 0.3 1.3 1 0 0 1 1 1 0 Endoplasmic reticulum vesicle transporter MIT PF04212.18 KFY03779.1 - 1.3e-14 54.0 0.4 3.3e-14 52.7 0.4 1.7 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain PXA PF02194.15 KFY03780.1 - 9.6e-30 103.9 0.1 5.5e-29 101.4 0.1 2.1 2 0 0 2 2 2 1 PXA domain Nexin_C PF08628.12 KFY03780.1 - 3.8e-23 82.2 0.0 1.6e-22 80.2 0.0 2.1 1 0 0 1 1 1 1 Sorting nexin C terminal PX PF00787.24 KFY03780.1 - 2.2e-08 34.1 0.0 2e-07 31.0 0.0 2.3 2 0 0 2 2 2 1 PX domain Flagellin_N PF00669.20 KFY03780.1 - 0.62 10.2 3.0 1.4 9.0 3.0 1.5 1 0 0 1 1 1 0 Bacterial flagellin N-terminal helical region PC4 PF02229.16 KFY03781.1 - 5.2e-20 70.8 0.0 9.4e-20 70.0 0.0 1.4 1 0 0 1 1 1 1 Transcriptional Coactivator p15 (PC4) DDHD PF02862.17 KFY03782.1 - 1.4e-63 215.1 1.6 2.5e-63 214.2 0.0 2.3 2 1 0 2 2 2 1 DDHD domain AAR2 PF05282.11 KFY03782.1 - 0.038 13.4 0.1 0.078 12.4 0.1 1.5 1 0 0 1 1 1 0 AAR2 protein DUF676 PF05057.14 KFY03782.1 - 0.099 12.1 0.2 0.75 9.3 0.0 2.4 3 0 0 3 3 3 0 Putative serine esterase (DUF676) WWE PF02825.20 KFY03782.1 - 0.11 13.2 0.0 4.5 8.0 0.0 3.0 2 0 0 2 2 2 0 WWE domain MGC-24 PF05283.11 KFY03787.1 - 0.06 13.8 3.6 1.7 9.1 0.8 2.2 2 0 0 2 2 2 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin DUF3597 PF12200.8 KFY03788.1 - 0.28 11.7 0.1 0.28 11.7 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3597) Self-incomp_S1 PF05938.11 KFY03789.1 - 0.072 13.6 4.3 0.12 13.0 4.2 1.5 1 1 0 1 1 1 0 Plant self-incompatibility protein S1 SecE PF00584.20 KFY03789.1 - 0.14 12.1 0.0 0.23 11.4 0.0 1.4 1 0 0 1 1 1 0 SecE/Sec61-gamma subunits of protein translocation complex DUF3844 PF12955.7 KFY03789.1 - 0.32 11.1 3.5 0.56 10.4 3.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3844) DUF5401 PF17380.2 KFY03790.1 - 0.06 11.4 21.9 0.071 11.2 21.9 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5401) RNA_pol_3_Rpc31 PF11705.8 KFY03790.1 - 0.25 11.6 14.2 0.26 11.5 14.2 1.1 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 Tim54 PF11711.8 KFY03790.1 - 0.27 10.0 10.9 0.32 9.7 10.9 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 DUF2228 PF10228.9 KFY03790.1 - 0.3 10.8 10.7 0.34 10.6 10.7 1.1 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2228) RPN2_C PF18004.1 KFY03790.1 - 1.1 9.2 19.7 1.2 9.1 19.7 1.3 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain Folate_carrier PF01770.18 KFY03790.1 - 1.1 7.9 5.0 1 8.0 5.0 1.1 1 0 0 1 1 1 0 Reduced folate carrier RR_TM4-6 PF06459.12 KFY03790.1 - 1.1 9.0 15.0 1.2 8.9 15.0 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF4407 PF14362.6 KFY03790.1 - 1.2 8.4 9.1 1.4 8.2 9.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Vfa1 PF08432.10 KFY03790.1 - 1.2 9.4 19.6 1.4 9.2 19.6 1.2 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 DUF4337 PF14235.6 KFY03790.1 - 1.4 9.0 13.0 1.8 8.6 13.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) AAA_11 PF13086.6 KFY03790.1 - 1.5 8.5 14.0 1.7 8.3 14.0 1.1 1 0 0 1 1 1 0 AAA domain DUF853 PF05872.12 KFY03790.1 - 1.9 7.0 6.3 2.1 6.9 6.3 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) Paramyxo_ncap PF00973.19 KFY03790.1 - 2.1 7.2 6.7 2.2 7.1 6.7 1.0 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein DcuA_DcuB PF03605.14 KFY03790.1 - 2.8 6.7 3.6 3.1 6.6 3.6 1.1 1 0 0 1 1 1 0 Anaerobic c4-dicarboxylate membrane transporter Connexin PF00029.19 KFY03790.1 - 2.8 7.6 10.3 3.2 7.5 10.3 1.2 1 0 0 1 1 1 0 Connexin YebO PF13974.6 KFY03790.1 - 2.9 8.1 10.2 4.4 7.4 10.2 1.4 1 0 0 1 1 1 0 YebO-like protein Membralin PF09746.9 KFY03790.1 - 3.8 6.5 7.4 4 6.4 7.4 1.0 1 0 0 1 1 1 0 Tumour-associated protein DDHD PF02862.17 KFY03790.1 - 5 7.2 7.5 5.5 7.1 7.5 1.1 1 0 0 1 1 1 0 DDHD domain DUF4820 PF16091.5 KFY03790.1 - 5.1 6.4 11.5 6.1 6.1 11.5 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) U79_P34 PF03064.16 KFY03790.1 - 5.5 6.3 18.5 6.7 6.0 18.5 1.1 1 0 0 1 1 1 0 HSV U79 / HCMV P34 Sec62 PF03839.16 KFY03790.1 - 5.5 6.4 15.9 7.6 6.0 15.9 1.2 1 0 0 1 1 1 0 Translocation protein Sec62 Ureide_permease PF07168.11 KFY03790.1 - 6.9 5.3 7.3 7.3 5.2 7.3 1.1 1 0 0 1 1 1 0 Ureide permease Presenilin PF01080.17 KFY03790.1 - 7.3 5.2 9.8 7.5 5.2 9.8 1.0 1 0 0 1 1 1 0 Presenilin NARP1 PF12569.8 KFY03790.1 - 7.6 5.3 22.1 8.4 5.2 22.1 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Borrelia_P83 PF05262.11 KFY03790.1 - 7.9 4.8 20.9 9.2 4.6 20.9 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein DUF2207 PF09972.9 KFY03791.1 - 7.8e-05 21.6 0.5 0.00093 18.1 0.5 2.3 1 1 0 1 1 1 1 Predicted membrane protein (DUF2207) Ca_hom_mod PF14798.6 KFY03791.1 - 0.0018 17.4 0.6 0.012 14.7 0.5 2.1 2 0 0 2 2 2 1 Calcium homeostasis modulator MTES_1575 PF18741.1 KFY03791.1 - 0.0028 17.8 0.1 0.0083 16.3 0.1 1.8 1 0 0 1 1 1 1 REase_MTES_1575 Orf78 PF06024.12 KFY03791.1 - 0.0046 17.2 0.4 0.04 14.2 0.1 2.4 3 0 0 3 3 3 1 Orf78 (ac78) FxsA PF04186.13 KFY03791.1 - 0.012 15.7 1.2 2.4 8.3 0.1 3.3 3 0 0 3 3 3 0 FxsA cytoplasmic membrane protein PAP1 PF08601.10 KFY03791.1 - 0.013 15.2 0.9 0.013 15.2 0.9 2.0 3 0 0 3 3 3 0 Transcription factor PAP1 SID-1_RNA_chan PF13965.6 KFY03791.1 - 0.017 13.6 0.1 0.017 13.6 0.1 1.7 2 1 0 2 2 2 0 dsRNA-gated channel SID-1 APG6_N PF17675.1 KFY03791.1 - 0.018 15.5 26.6 0.81 10.2 12.9 3.2 3 0 0 3 3 3 0 Apg6 coiled-coil region T2SSM_b PF10741.9 KFY03791.1 - 0.062 13.1 1.5 0.15 11.8 0.2 2.3 2 1 0 2 2 2 0 Type II secretion system (T2SS), protein M subtype b DUF1129 PF06570.11 KFY03791.1 - 0.086 12.3 0.6 9.4 5.7 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1129) Connexin PF00029.19 KFY03791.1 - 0.18 11.5 2.3 0.28 10.9 1.0 1.9 2 0 0 2 2 2 0 Connexin EOS1 PF12326.8 KFY03791.1 - 0.32 10.9 1.6 2.5 8.0 1.0 2.3 2 0 0 2 2 2 0 N-glycosylation protein DUF3450 PF11932.8 KFY03791.1 - 0.57 9.4 18.9 0.73 9.1 7.9 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3450) EMC3_TMCO1 PF01956.16 KFY03791.1 - 0.69 9.6 5.3 1.2 8.9 2.2 2.3 2 0 0 2 2 2 0 Integral membrane protein EMC3/TMCO1-like DUF3446 PF11928.8 KFY03791.1 - 1.1 9.7 10.2 6.8 7.1 0.5 2.4 2 0 0 2 2 2 0 Early growth response N-terminal domain LCD1 PF09798.9 KFY03791.1 - 1.5 7.3 10.0 2 6.8 1.9 2.2 2 0 0 2 2 2 0 DNA damage checkpoint protein LRRC37AB_C PF14914.6 KFY03791.1 - 2.4 8.1 7.2 0.24 11.3 1.1 2.3 3 0 0 3 3 3 0 LRRC37A/B like protein 1 C-terminal domain Mito_fiss_reg PF05308.11 KFY03791.1 - 3.1 7.8 14.7 0.68 10.0 0.5 3.1 3 0 0 3 3 3 0 Mitochondrial fission regulator DUF4366 PF14283.6 KFY03791.1 - 4.9 7.2 9.0 0.17 11.9 0.8 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4366) NapE PF06796.11 KFY03791.1 - 7.7 6.1 9.3 0.14 11.7 0.3 2.6 3 0 0 3 3 3 0 Periplasmic nitrate reductase protein NapE OmpH PF03938.14 KFY03791.1 - 9.6 6.5 31.2 3 8.2 2.0 3.1 3 0 0 3 3 3 0 Outer membrane protein (OmpH-like) Pyr_redox_3 PF13738.6 KFY03792.1 - 3.7e-14 52.7 0.1 1.2e-10 41.1 0.0 3.0 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 KFY03792.1 - 7.8e-14 51.0 0.1 1e-12 47.3 0.2 2.4 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 KFY03792.1 - 2.6e-13 49.9 0.0 5.4e-11 42.3 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KFY03792.1 - 1.6e-11 43.9 0.0 3.4e-09 36.3 0.0 2.9 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 KFY03792.1 - 3.4e-07 30.4 0.4 4.4e-06 26.8 0.1 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 KFY03792.1 - 5.5e-06 26.8 1.8 0.011 16.3 0.0 2.8 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KFY03792.1 - 8.2e-05 22.6 3.5 0.0091 16.0 0.2 3.8 3 1 1 4 4 4 1 FAD-NAD(P)-binding AlaDh_PNT_C PF01262.21 KFY03792.1 - 0.00012 21.5 0.1 0.16 11.3 0.0 2.2 2 0 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain DAO PF01266.24 KFY03792.1 - 0.00037 20.2 6.4 0.00059 19.5 1.3 3.0 2 1 1 3 3 3 1 FAD dependent oxidoreductase HI0933_like PF03486.14 KFY03792.1 - 0.011 14.4 0.6 0.63 8.7 0.1 2.9 3 0 0 3 3 3 0 HI0933-like protein 3HCDH_N PF02737.18 KFY03792.1 - 0.016 15.1 0.3 0.029 14.3 0.3 1.5 1 1 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Shikimate_DH PF01488.20 KFY03792.1 - 0.027 14.6 0.1 4.2 7.4 0.0 2.3 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase FAD_binding_2 PF00890.24 KFY03792.1 - 1.2 8.2 5.5 0.087 11.9 0.4 1.7 3 0 0 3 3 3 0 FAD binding domain His_Phos_1 PF00300.22 KFY03793.1 - 0.00014 21.7 2.1 0.87 9.2 0.0 4.0 4 0 0 4 4 4 3 Histidine phosphatase superfamily (branch 1) Peptidase_C13 PF01650.18 KFY03794.1 - 6.4e-41 140.6 0.0 8.1e-41 140.2 0.0 1.1 1 0 0 1 1 1 1 Peptidase C13 family ELF PF03317.13 KFY03794.1 - 0.11 12.6 0.1 0.18 11.8 0.1 1.3 1 0 0 1 1 1 0 ELF protein EF-hand_1 PF00036.32 KFY03796.1 - 8.3e-25 84.5 11.7 3.4e-08 32.5 0.1 4.8 5 0 0 5 5 5 3 EF hand EF-hand_6 PF13405.6 KFY03796.1 - 7.2e-24 81.6 4.1 5.3e-06 25.9 0.1 5.2 5 0 0 5 5 5 4 EF-hand domain EF-hand_7 PF13499.6 KFY03796.1 - 1.7e-23 82.8 9.0 1.4e-14 54.3 1.1 3.0 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_5 PF13202.6 KFY03796.1 - 1.1e-16 59.4 13.3 4.7e-05 22.7 0.1 4.6 5 0 0 5 5 5 4 EF hand EF-hand_8 PF13833.6 KFY03796.1 - 2.1e-15 56.3 10.8 2.9e-05 23.8 0.8 3.9 2 2 1 3 3 3 3 EF-hand domain pair EF-hand_4 PF12763.7 KFY03796.1 - 7.4e-09 35.5 7.4 0.0019 18.2 0.2 4.0 1 1 3 4 4 4 3 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.6 KFY03796.1 - 0.00032 21.0 0.6 0.015 15.6 0.0 2.9 2 1 1 3 3 3 2 EF-hand domain SPARC_Ca_bdg PF10591.9 KFY03796.1 - 0.001 19.4 2.3 0.76 10.1 0.3 3.1 2 1 0 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region DUF1679 PF07914.11 KFY03796.1 - 0.0041 16.0 0.6 0.33 9.7 0.2 2.1 1 1 0 2 2 2 2 Protein of unknown function (DUF1679) EF-hand_10 PF14788.6 KFY03796.1 - 0.12 12.3 4.6 0.26 11.2 0.1 3.4 5 0 0 5 5 5 0 EF hand EF-hand_2 PF09068.11 KFY03796.1 - 0.14 12.3 0.0 2.1 8.5 0.0 2.5 3 1 0 3 3 3 0 EF hand EF-hand_14 PF17959.1 KFY03796.1 - 0.39 11.1 2.2 13 6.2 0.0 3.4 4 0 0 4 4 4 0 EF-hand domain Med4 PF10018.9 KFY03797.1 - 2.1e-36 125.4 7.8 4.1e-36 124.5 7.8 1.4 1 1 0 1 1 1 1 Vitamin-D-receptor interacting Mediator subunit 4 DUF1682 PF07946.14 KFY03797.1 - 0.0015 17.8 3.2 0.002 17.4 3.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1682) HIP1_clath_bdg PF16515.5 KFY03797.1 - 0.63 10.7 10.7 1.3 9.7 6.2 2.3 2 0 0 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 TMEM247 PF15444.6 KFY03797.1 - 2.2 8.3 8.9 0.12 12.4 3.4 1.6 2 0 0 2 2 2 0 Transmembrane protein 247 Sas10_Utp3 PF04000.15 KFY03798.1 - 2.8e-18 66.3 1.1 6.5e-18 65.1 1.1 1.6 1 0 0 1 1 1 1 Sas10/Utp3/C1D family EMP70 PF02990.16 KFY03799.1 - 4.6e-204 678.9 2.4 6.4e-204 678.4 2.4 1.2 1 0 0 1 1 1 1 Endomembrane protein 70 Pectate_lyase PF03211.13 KFY03800.1 - 4.4e-83 277.8 9.9 7.1e-83 277.1 9.9 1.3 1 0 0 1 1 1 1 Pectate lyase MSP1_C PF07462.11 KFY03800.1 - 0.8 8.3 1.6 1 8.0 1.6 1.2 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus MFS_1 PF07690.16 KFY03801.1 - 3.6e-36 124.8 26.2 3.6e-36 124.8 26.2 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily YwiC PF14256.6 KFY03801.1 - 6.2 7.2 12.5 0.1 12.9 0.9 3.2 3 1 0 3 3 3 0 YwiC-like protein Arylsulfotran_2 PF14269.6 KFY03802.1 - 2.1e-21 76.6 0.0 3.4e-21 75.9 0.0 1.3 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) Arylsulfotrans PF05935.11 KFY03802.1 - 1.7e-20 73.3 0.0 1.6e-09 37.2 0.0 3.1 1 1 1 2 2 2 2 Arylsulfotransferase (ASST) PQQ_2 PF13360.6 KFY03802.1 - 7.5e-05 22.4 0.0 0.00062 19.4 0.0 2.2 2 1 0 2 2 2 1 PQQ-like domain B_lectin PF01453.24 KFY03802.1 - 0.05 14.2 0.1 0.28 11.7 0.1 2.2 2 1 0 2 2 2 0 D-mannose binding lectin Transferase PF02458.15 KFY03803.1 - 3.2e-09 35.9 0.0 5.7e-09 35.1 0.0 1.4 1 0 0 1 1 1 1 Transferase family WW_like PF17890.1 KFY03804.1 - 0.08 13.0 0.0 0.16 12.0 0.0 1.5 1 0 0 1 1 1 0 Peptidoglycan hydrolase LytB WW-like domain UBX PF00789.20 KFY03804.1 - 0.099 12.9 0.0 0.22 11.7 0.0 1.5 1 0 0 1 1 1 0 UBX domain TEX15 PF15326.6 KFY03804.1 - 0.2 11.4 0.0 0.27 10.9 0.0 1.2 1 0 0 1 1 1 0 Testis expressed sequence 15 JIP_LZII PF16471.5 KFY03805.1 - 0.0073 16.5 1.8 0.0073 16.5 1.8 2.2 3 0 0 3 3 3 1 JNK-interacting protein leucine zipper II DUF4407 PF14362.6 KFY03805.1 - 0.089 12.1 5.7 0.14 11.5 0.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) DUF4140 PF13600.6 KFY03805.1 - 3.2 8.2 6.4 8.9 6.8 1.3 2.5 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) V-ATPase_G PF03179.15 KFY03805.1 - 7.5 7.1 8.4 1 10.0 1.1 2.4 2 0 0 2 2 2 0 Vacuolar (H+)-ATPase G subunit PQ-loop PF04193.14 KFY03806.1 - 3e-06 26.9 1.0 7.2e-06 25.7 1.0 1.7 1 1 0 1 1 1 1 PQ loop repeat GATase_5 PF13507.6 KFY03807.1 - 8.7e-101 336.4 0.0 1.4e-100 335.7 0.0 1.3 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain AIRS_C PF02769.22 KFY03807.1 - 1.9e-40 138.5 1.1 8.4e-26 91.0 0.1 3.4 3 0 0 3 3 3 2 AIR synthase related protein, C-terminal domain FGAR-AT_N PF18076.1 KFY03807.1 - 6.3e-25 87.4 0.0 1.3e-24 86.4 0.0 1.6 1 0 0 1 1 1 1 Formylglycinamide ribonucleotide amidotransferase N-terminal FGAR-AT_linker PF18072.1 KFY03807.1 - 8.1e-22 77.5 0.0 1.9e-21 76.3 0.0 1.7 1 0 0 1 1 1 1 Formylglycinamide ribonucleotide amidotransferase linker domain AIRS PF00586.24 KFY03807.1 - 0.0095 16.6 0.1 3.7 8.3 0.0 3.4 3 0 0 3 3 3 1 AIR synthase related protein, N-terminal domain TPR_2 PF07719.17 KFY03808.1 - 3.4e-33 111.1 1.0 2.3e-05 24.1 0.0 10.5 10 0 0 10 10 10 6 Tetratricopeptide repeat ANAPC3 PF12895.7 KFY03808.1 - 9.9e-32 109.0 8.4 9.6e-25 86.6 0.1 5.5 4 2 2 6 6 6 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_1 PF00515.28 KFY03808.1 - 9.3e-29 98.1 0.0 1.1e-05 25.0 0.0 9.5 9 0 0 9 9 9 6 Tetratricopeptide repeat TPR_19 PF14559.6 KFY03808.1 - 1.3e-25 89.6 1.6 0.0018 18.7 0.0 7.7 6 2 2 8 8 8 4 Tetratricopeptide repeat TPR_12 PF13424.6 KFY03808.1 - 3.6e-24 84.8 4.5 1.3e-10 41.4 0.0 8.4 8 1 0 8 8 8 2 Tetratricopeptide repeat TPR_8 PF13181.6 KFY03808.1 - 8.3e-24 81.8 0.0 0.0036 17.4 0.1 9.5 9 0 0 9 9 9 4 Tetratricopeptide repeat TPR_16 PF13432.6 KFY03808.1 - 3.7e-18 65.9 0.8 9.3e-07 29.4 0.0 7.5 6 3 1 7 7 7 4 Tetratricopeptide repeat TPR_14 PF13428.6 KFY03808.1 - 3.8e-18 64.6 2.4 0.0035 18.0 0.0 9.4 5 3 4 9 9 9 3 Tetratricopeptide repeat TPR_7 PF13176.6 KFY03808.1 - 1.6e-16 59.0 3.8 1.3e-05 24.8 0.0 8.0 9 0 0 9 9 8 1 Tetratricopeptide repeat TPR_10 PF13374.6 KFY03808.1 - 5.7e-15 54.6 1.2 9.5e-07 28.5 0.0 7.2 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_11 PF13414.6 KFY03808.1 - 6.9e-14 51.3 0.1 3.2e-05 23.5 0.0 6.8 6 2 1 7 7 7 2 TPR repeat TPR_6 PF13174.6 KFY03808.1 - 1.4e-13 50.5 2.5 0.061 14.0 0.0 7.9 8 0 0 8 8 7 2 Tetratricopeptide repeat TPR_4 PF07721.14 KFY03808.1 - 2.5e-09 36.8 0.3 0.0095 16.5 0.1 5.0 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_9 PF13371.6 KFY03808.1 - 3.2e-08 33.6 0.3 0.0017 18.4 0.0 5.2 6 0 0 6 6 5 1 Tetratricopeptide repeat TPR_15 PF13429.6 KFY03808.1 - 5.8e-05 22.4 0.1 1.6 7.9 0.0 5.0 3 2 3 6 6 6 1 Tetratricopeptide repeat TPR_17 PF13431.6 KFY03808.1 - 0.00019 21.6 0.3 46 4.7 0.1 7.0 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_MalT PF17874.1 KFY03808.1 - 0.00026 20.5 2.9 0.032 13.6 0.0 4.4 4 2 1 5 5 4 1 MalT-like TPR region DUF3856 PF12968.7 KFY03808.1 - 0.00039 20.5 0.4 0.097 12.7 0.0 3.4 3 0 0 3 3 3 1 Domain of Unknown Function (DUF3856) PPR PF01535.20 KFY03808.1 - 0.001 19.1 4.9 0.23 11.8 0.1 4.5 4 0 0 4 4 4 1 PPR repeat SRP_TPR_like PF17004.5 KFY03808.1 - 0.0013 18.8 0.1 0.42 10.6 0.0 3.4 3 1 1 4 4 4 1 Putative TPR-like repeat RPN7 PF10602.9 KFY03808.1 - 0.0025 17.5 0.2 2.1 8.1 0.0 4.4 2 1 1 3 3 3 1 26S proteasome subunit RPN7 HrpB1_HrpK PF09613.10 KFY03808.1 - 0.0027 17.3 0.0 11 5.7 0.0 4.2 4 1 0 4 4 4 0 Bacterial type III secretion protein (HrpB1_HrpK) TPR_5 PF12688.7 KFY03808.1 - 0.024 14.9 0.2 0.32 11.2 0.0 2.9 4 0 0 4 4 2 0 Tetratrico peptide repeat TPR_21 PF09976.9 KFY03808.1 - 0.033 13.9 5.1 9.2 5.9 0.2 4.7 5 1 2 7 7 7 0 Tetratricopeptide repeat-like domain Ribosomal_L27 PF01016.19 KFY03809.1 - 1.2e-31 108.6 0.1 3.1e-31 107.2 0.1 1.8 1 0 0 1 1 1 1 Ribosomal L27 protein tRNA-synt_1c PF00749.21 KFY03811.1 - 5.5e-105 350.7 0.1 7.2e-105 350.3 0.1 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.18 KFY03811.1 - 4.4e-39 134.1 0.1 7.6e-39 133.4 0.1 1.4 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain tRNA-synt_1e PF01406.19 KFY03811.1 - 0.015 14.6 0.5 0.044 13.1 0.2 1.7 1 1 1 2 2 2 0 tRNA synthetases class I (C) catalytic domain DUF3673 PF12425.8 KFY03811.1 - 0.12 12.3 0.2 14 5.7 0.0 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3673) Ribosomal_L1 PF00687.21 KFY03812.1 - 4.7e-31 108.1 0.0 8e-31 107.4 0.0 1.4 1 1 0 1 1 1 1 Ribosomal protein L1p/L10e family FlgT_C PF16538.5 KFY03812.1 - 0.09 13.3 0.2 5 7.7 0.1 2.4 2 0 0 2 2 2 0 Flagellar assembly protein T, C-terminal domain COG2 PF06148.11 KFY03813.1 - 1.6e-28 99.4 0.7 2.7e-28 98.7 0.7 1.4 1 0 0 1 1 1 1 COG (conserved oligomeric Golgi) complex component, COG2 Vps51 PF08700.11 KFY03813.1 - 2.6e-05 24.2 0.9 0.0007 19.6 0.0 2.4 2 0 0 2 2 2 1 Vps51/Vps67 Spc7 PF08317.11 KFY03813.1 - 0.00028 19.9 0.9 0.00041 19.3 0.9 1.2 1 0 0 1 1 1 1 Spc7 kinetochore protein AlkA_N PF06029.11 KFY03813.1 - 0.2 11.9 2.2 0.47 10.7 0.0 2.5 3 0 0 3 3 3 0 AlkA N-terminal domain Hap4_Hap_bind PF10297.9 KFY03814.1 - 7.5e-06 25.9 9.4 7.5e-06 25.9 9.4 3.1 3 0 0 3 3 3 1 Minimal binding motif of Hap4 for binding to Hap2/3/5 bZIP_1 PF00170.21 KFY03814.1 - 0.00014 21.9 7.9 0.00014 21.9 7.9 2.0 2 0 0 2 2 2 1 bZIP transcription factor dsrm PF00035.26 KFY03814.1 - 0.14 12.9 0.0 0.38 11.5 0.0 1.7 1 0 0 1 1 1 0 Double-stranded RNA binding motif DUF1664 PF07889.12 KFY03814.1 - 0.28 11.2 0.6 0.77 9.8 0.6 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Adaptin_binding PF10199.9 KFY03814.1 - 0.92 10.1 9.0 2.4 8.8 9.0 1.6 1 0 0 1 1 1 0 Alpha and gamma adaptin binding protein p34 Stathmin PF00836.19 KFY03814.1 - 1.1 9.2 12.2 2.3 8.2 12.2 1.5 1 0 0 1 1 1 0 Stathmin family Spc7 PF08317.11 KFY03814.1 - 2.1 7.1 12.2 3.5 6.4 12.2 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein TPR_2 PF07719.17 KFY03815.1 - 0.00097 19.1 0.1 0.98 9.7 0.1 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat UBA PF00627.31 KFY03815.1 - 0.011 15.6 0.0 0.024 14.6 0.0 1.6 1 0 0 1 1 1 0 UBA/TS-N domain TPR_8 PF13181.6 KFY03815.1 - 0.033 14.4 0.0 9.1 6.8 0.0 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.6 KFY03815.1 - 0.077 13.3 0.1 1.6 9.1 0.0 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_1 PF00515.28 KFY03815.1 - 0.12 12.2 0.0 2.5 8.1 0.0 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat DnaJ PF00226.31 KFY03815.1 - 0.23 11.6 1.6 0.33 11.1 0.0 2.1 2 0 0 2 2 2 0 DnaJ domain PhoD PF09423.10 KFY03816.1 - 2.2e-41 142.1 0.0 5.3e-41 140.8 0.0 1.6 1 0 0 1 1 1 1 PhoD-like phosphatase SGS PF05002.15 KFY03816.1 - 2e-32 111.1 1.5 4.3e-32 110.1 1.5 1.6 1 0 0 1 1 1 1 SGS domain CS PF04969.16 KFY03816.1 - 3.7e-16 59.9 0.1 1.1e-15 58.4 0.1 1.9 1 0 0 1 1 1 1 CS domain TPR_2 PF07719.17 KFY03816.1 - 0.0032 17.5 4.7 3.6 7.9 0.1 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 KFY03816.1 - 0.025 14.4 4.5 2.8 7.9 0.4 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF2057 PF09829.9 KFY03816.1 - 0.3 11.2 2.7 4.5 7.4 0.1 2.4 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2057) TPR_19 PF14559.6 KFY03816.1 - 0.85 10.2 3.9 1 9.9 1.7 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.6 KFY03816.1 - 4 7.8 11.7 3.4 8.0 2.4 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat Pkinase PF00069.25 KFY03817.1 - 1.8e-69 234.1 0.0 2.7e-69 233.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFY03817.1 - 5.4e-46 157.0 0.0 1.2e-45 155.8 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KFY03817.1 - 8.8e-06 24.7 0.2 2.6e-05 23.2 0.0 1.8 2 0 0 2 2 2 1 Fungal protein kinase Kinase-like PF14531.6 KFY03817.1 - 0.00017 21.0 0.0 0.0011 18.4 0.0 2.1 2 0 0 2 2 2 1 Kinase-like hNIFK_binding PF12196.8 KFY03817.1 - 0.14 11.7 2.6 0.4 10.2 2.6 1.9 1 0 0 1 1 1 0 FHA Ki67 binding domain of hNIFK YABBY PF04690.13 KFY03817.1 - 2.5 8.6 5.0 0.38 11.3 0.3 1.9 2 0 0 2 2 2 0 YABBY protein MAJIN PF15077.6 KFY03817.1 - 4 7.1 6.4 1.9 8.3 0.8 2.3 2 0 0 2 2 2 0 Membrane-anchored junction protein Transglut_core PF01841.19 KFY03818.1 - 3.9e-12 46.6 0.1 1.3e-11 45.0 0.1 1.9 1 0 0 1 1 1 1 Transglutaminase-like superfamily SH3_2 PF07653.17 KFY03818.1 - 4.2e-09 35.9 0.1 2e-08 33.8 0.1 2.3 2 0 0 2 2 2 1 Variant SH3 domain SH3_1 PF00018.28 KFY03818.1 - 7.1e-06 25.5 0.0 2.9e-05 23.6 0.0 2.2 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KFY03818.1 - 0.023 14.5 0.1 0.059 13.2 0.1 1.8 1 0 0 1 1 1 0 Variant SH3 domain Transglut_core2 PF13369.6 KFY03818.1 - 0.066 12.8 0.0 0.18 11.4 0.0 1.7 2 0 0 2 2 2 0 Transglutaminase-like superfamily SnoaL_4 PF13577.6 KFY03819.1 - 1.8e-22 79.9 0.0 2.1e-22 79.6 0.0 1.1 1 0 0 1 1 1 1 SnoaL-like domain DUF4440 PF14534.6 KFY03819.1 - 0.018 15.5 0.0 0.026 14.9 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4440) Scytalone_dh PF02982.14 KFY03819.1 - 0.047 13.5 0.1 0.1 12.4 0.1 1.6 1 1 0 1 1 1 0 Scytalone dehydratase MTHFR PF02219.17 KFY03820.1 - 1.7e-110 368.8 0.0 2.5e-110 368.3 0.0 1.1 1 0 0 1 1 1 1 Methylenetetrahydrofolate reductase NOG1_N PF17835.1 KFY03822.1 - 3e-49 167.1 0.7 1.1e-48 165.3 0.1 2.2 2 0 0 2 2 2 1 NOG1 N-terminal helical domain NOGCT PF08155.11 KFY03822.1 - 9.8e-28 95.9 4.5 1.1e-27 95.8 3.0 1.9 2 0 0 2 2 2 1 NOGCT (NUC087) domain NOG1 PF06858.14 KFY03822.1 - 1.1e-25 89.2 0.4 2.3e-25 88.1 0.4 1.6 1 0 0 1 1 1 1 Nucleolar GTP-binding protein 1 (NOG1) MMR_HSR1 PF01926.23 KFY03822.1 - 1.9e-15 56.9 0.0 4.3e-15 55.8 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 KFY03822.1 - 3.4e-08 33.2 0.0 8.6e-08 31.9 0.0 1.7 1 1 0 1 1 1 1 Ferrous iron transport protein B AAA_16 PF13191.6 KFY03822.1 - 0.0019 18.6 0.4 0.1 13.0 0.1 3.4 3 1 0 3 3 3 1 AAA ATPase domain RsgA_GTPase PF03193.16 KFY03822.1 - 0.0024 17.8 0.1 0.43 10.5 0.0 3.0 3 1 0 3 3 3 1 RsgA GTPase Dynamin_N PF00350.23 KFY03822.1 - 0.027 14.5 0.0 7.2 6.6 0.0 2.7 1 1 1 2 2 2 0 Dynamin family AAA_33 PF13671.6 KFY03822.1 - 3 8.0 6.5 40 4.3 1.3 3.5 4 0 0 4 4 4 0 AAA domain Asp_protease PF09668.10 KFY03823.1 - 2.2e-62 208.4 0.2 3.3e-62 207.8 0.2 1.3 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 KFY03823.1 - 4.2e-24 84.9 0.0 8.3e-24 84.0 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 KFY03823.1 - 2.3e-11 44.2 0.0 4.5e-11 43.2 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease ubiquitin PF00240.23 KFY03823.1 - 2.5e-10 40.0 0.1 4.3e-10 39.2 0.1 1.4 1 0 0 1 1 1 1 Ubiquitin family UBA PF00627.31 KFY03823.1 - 7.7e-09 35.3 0.1 2.1e-08 33.9 0.1 1.7 1 0 0 1 1 1 1 UBA/TS-N domain UN_NPL4 PF11543.8 KFY03823.1 - 9.6e-05 22.8 0.0 0.00021 21.7 0.0 1.5 1 0 0 1 1 1 1 Nuclear pore localisation protein NPL4 RVP_2 PF08284.11 KFY03823.1 - 0.0002 21.1 0.0 0.00034 20.4 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease Rad60-SLD PF11976.8 KFY03823.1 - 0.00044 20.0 0.1 0.0012 18.6 0.0 1.8 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like YukD PF08817.10 KFY03823.1 - 0.0013 19.4 0.3 0.0043 17.7 0.3 2.0 1 0 0 1 1 1 1 WXG100 protein secretion system (Wss), protein YukD RVP PF00077.20 KFY03823.1 - 0.0024 18.1 0.0 0.007 16.6 0.0 1.8 1 0 0 1 1 1 1 Retroviral aspartyl protease UBA_4 PF14555.6 KFY03823.1 - 0.021 14.6 1.6 0.038 13.8 0.3 2.1 2 0 0 2 2 2 0 UBA-like domain RuvA_C PF07499.13 KFY03823.1 - 0.12 12.9 0.0 0.42 11.1 0.0 2.0 1 0 0 1 1 1 0 RuvA, C-terminal domain Methyltransf_8 PF05148.15 KFY03824.1 - 4.2e-55 187.0 0.1 5e-53 180.2 0.0 2.9 3 1 0 3 3 3 1 Hypothetical methyltransferase Methyltransf_11 PF08241.12 KFY03824.1 - 7.7e-06 26.5 0.0 4.2e-05 24.1 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KFY03824.1 - 5.5e-05 23.8 0.0 0.012 16.3 0.0 2.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.6 KFY03824.1 - 0.0067 16.4 0.0 0.0067 16.4 0.0 2.7 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 KFY03824.1 - 0.013 15.3 0.1 2.5 7.9 0.0 2.3 2 0 0 2 2 2 0 Methyltransferase domain MTS PF05175.14 KFY03824.1 - 0.076 12.6 0.0 4.6 6.8 0.0 2.4 2 0 0 2 2 2 0 Methyltransferase small domain Fungal_trans_2 PF11951.8 KFY03825.1 - 2.7e-20 72.5 1.7 5.3e-13 48.5 0.9 3.2 3 0 0 3 3 3 3 Fungal specific transcription factor domain Zn_clus PF00172.18 KFY03825.1 - 1.6e-07 31.3 10.7 2.8e-07 30.6 10.7 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Proteasome PF00227.26 KFY03826.1 - 1e-56 191.4 0.1 1.3e-56 191.1 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 KFY03826.1 - 1.8e-12 46.7 0.0 3.6e-12 45.7 0.0 1.5 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature GCP_N_terminal PF17681.1 KFY03827.1 - 1.7e-65 221.7 0.0 3.3e-65 220.7 0.0 1.4 1 0 0 1 1 1 1 Gamma tubulin complex component N-terminal GCP_C_terminal PF04130.13 KFY03827.1 - 2.2e-61 208.0 8.0 2.2e-61 208.0 8.0 1.7 2 0 0 2 2 2 1 Gamma tubulin complex component C-terminal TipAS PF07739.13 KFY03827.1 - 0.083 13.4 0.5 2 9.0 0.0 2.7 2 0 0 2 2 2 0 TipAS antibiotic-recognition domain YqeY PF09424.10 KFY03828.1 - 6.5e-18 65.2 8.9 7.4e-18 65.0 8.9 1.0 1 0 0 1 1 1 1 Yqey-like protein 4HBT_3 PF13622.6 KFY03833.1 - 4.4e-40 138.5 0.0 5.3e-40 138.2 0.0 1.0 1 0 0 1 1 1 1 Thioesterase-like superfamily Acyl_CoA_thio PF02551.15 KFY03833.1 - 4.5e-18 65.4 0.0 9.2e-11 41.7 0.0 2.1 2 0 0 2 2 2 2 Acyl-CoA thioesterase Polysacc_lyase PF14099.6 KFY03833.1 - 0.077 12.8 0.1 0.09 12.6 0.1 1.2 1 1 0 1 1 1 0 Polysaccharide lyase Oxysterol_BP PF01237.18 KFY03834.1 - 1.5e-133 445.3 0.7 9e-133 442.7 0.0 2.1 2 0 0 2 2 2 1 Oxysterol-binding protein ATP12 PF07542.11 KFY03834.1 - 9.4e-44 148.6 0.2 2.2e-43 147.4 0.2 1.7 1 0 0 1 1 1 1 ATP12 chaperone protein GAT PF03127.14 KFY03834.1 - 4.5e-19 68.5 2.5 4.4e-17 62.2 0.9 2.8 2 0 0 2 2 2 1 GAT domain Ank_5 PF13857.6 KFY03834.1 - 4.3e-18 65.1 1.9 7.9e-10 38.8 0.0 4.7 3 1 1 4 4 4 2 Ankyrin repeats (many copies) Ank PF00023.30 KFY03834.1 - 4.9e-14 52.0 1.0 0.0003 21.1 0.1 4.0 3 0 0 3 3 3 3 Ankyrin repeat Ank_2 PF12796.7 KFY03834.1 - 2e-13 50.7 0.3 1.9e-08 34.8 0.0 3.4 3 0 0 3 3 3 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KFY03834.1 - 2e-12 47.4 0.0 2.6e-07 31.1 0.0 2.7 2 0 0 2 2 2 2 Ankyrin repeats (many copies) PH PF00169.29 KFY03834.1 - 5.9e-12 46.0 1.0 2.5e-11 44.0 1.0 2.1 2 0 0 2 2 2 1 PH domain Ank_3 PF13606.6 KFY03834.1 - 1.2e-11 43.8 0.3 0.00043 20.5 0.0 3.9 3 0 0 3 3 3 2 Ankyrin repeat PH_8 PF15409.6 KFY03834.1 - 4e-07 30.2 0.9 1.5e-06 28.4 0.8 2.1 2 0 0 2 2 2 1 Pleckstrin homology domain PH_11 PF15413.6 KFY03834.1 - 0.00019 21.8 3.7 0.00065 20.1 3.7 2.0 1 0 0 1 1 1 1 Pleckstrin homology domain AGOG PF09171.10 KFY03834.1 - 0.0054 16.1 0.1 0.01 15.2 0.1 1.3 1 0 0 1 1 1 1 N-glycosylase/DNA lyase VHS PF00790.19 KFY03834.1 - 0.022 14.6 0.1 0.061 13.2 0.1 1.7 1 0 0 1 1 1 0 VHS domain UBA_4 PF14555.6 KFY03835.1 - 2.4e-11 43.3 0.3 4.9e-11 42.3 0.3 1.6 1 0 0 1 1 1 1 UBA-like domain UBX PF00789.20 KFY03835.1 - 2.1e-08 34.3 0.0 4.3e-08 33.2 0.0 1.6 1 0 0 1 1 1 1 UBX domain DUF1682 PF07946.14 KFY03835.1 - 0.0031 16.8 1.3 0.0051 16.1 1.3 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1682) TAF4 PF05236.14 KFY03835.1 - 0.014 15.2 4.0 0.019 14.7 4.0 1.2 1 0 0 1 1 1 0 Transcription initiation factor TFIID component TAF4 family Phage_Mu_F PF04233.14 KFY03835.1 - 1.4 9.7 6.5 3.3 8.5 6.5 1.6 1 0 0 1 1 1 0 Phage Mu protein F like protein Pan3_PK PF18101.1 KFY03836.1 - 1.3e-63 213.1 0.1 2.1e-63 212.4 0.1 1.3 1 0 0 1 1 1 1 Pan3 Pseudokinase domain Pkinase PF00069.25 KFY03836.1 - 3.4e-05 23.3 0.0 5.9e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Tis11B_N PF04553.12 KFY03836.1 - 0.07 13.7 0.7 1.3 9.6 0.0 2.7 2 0 0 2 2 2 0 Tis11B like protein, N terminus zf-CCCH PF00642.24 KFY03836.1 - 0.14 12.1 0.7 0.27 11.2 0.7 1.5 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) DUF1850 PF08905.11 KFY03837.1 - 0.039 14.3 0.1 0.047 14.0 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1850) Osmo_CC PF08946.10 KFY03837.1 - 0.23 11.7 2.5 0.6 10.4 0.3 2.2 1 1 1 2 2 2 0 Osmosensory transporter coiled coil Peptidase_M43 PF05572.13 KFY03845.1 - 5.9e-16 58.7 0.0 9.7e-16 58.0 0.0 1.3 1 0 0 1 1 1 1 Pregnancy-associated plasma protein-A Peptidase_M10 PF00413.24 KFY03845.1 - 0.00015 21.6 0.0 0.00018 21.4 0.0 1.2 1 0 0 1 1 1 1 Matrixin Reprolysin_4 PF13583.6 KFY03845.1 - 0.0033 17.1 1.3 0.0038 16.9 0.1 1.7 2 1 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.6 KFY03845.1 - 0.0044 17.2 0.4 0.0076 16.4 0.4 1.6 1 1 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_3 PF13582.6 KFY03845.1 - 0.015 15.9 2.8 0.28 11.7 1.9 2.7 2 1 0 2 2 2 0 Metallo-peptidase family M12B Reprolysin-like DUF4953 PF16313.5 KFY03845.1 - 0.12 11.6 0.0 0.19 10.9 0.0 1.3 1 0 0 1 1 1 0 Met-zincin Sugar_tr PF00083.24 KFY03848.1 - 6.8e-82 275.7 22.6 7.8e-82 275.5 22.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KFY03848.1 - 1.8e-20 73.2 29.6 1.8e-20 73.2 29.6 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF3464 PF11947.8 KFY03848.1 - 0.93 9.2 2.4 2 8.2 2.4 1.5 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 IBV_3C PF03620.13 KFY03848.1 - 4.9 7.7 6.7 6.5 7.3 0.0 3.2 3 0 0 3 3 3 0 IBV 3C protein Sulfatase PF00884.23 KFY03849.1 - 2.3e-67 227.6 0.1 3e-67 227.2 0.1 1.2 1 0 0 1 1 1 1 Sulfatase DUF4976 PF16347.5 KFY03849.1 - 6.4e-21 74.5 5.4 3.5e-20 72.2 5.4 2.1 1 1 0 1 1 1 1 Domain of unknown function (DUF4976) Phosphodiest PF01663.22 KFY03849.1 - 2.9e-10 40.3 0.8 0.00046 19.9 0.0 2.6 2 1 0 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase DUF229 PF02995.17 KFY03849.1 - 0.025 13.2 0.0 0.041 12.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF229) RepL PF05732.11 KFY03849.1 - 0.09 12.2 0.3 0.15 11.5 0.3 1.3 1 0 0 1 1 1 0 Firmicute plasmid replication protein (RepL) Glyco_hydro_20 PF00728.22 KFY03850.1 - 2.7e-78 263.9 0.0 3.3e-78 263.6 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Glycohydro_20b2 PF14845.6 KFY03850.1 - 8e-30 104.3 0.0 2e-29 103.0 0.0 1.6 2 0 0 2 2 2 1 beta-acetyl hexosaminidase like Glyco_hydro_20b PF02838.15 KFY03850.1 - 4.1e-05 24.4 0.1 0.00029 21.6 0.1 2.1 1 1 0 1 1 1 1 Glycosyl hydrolase family 20, domain 2 ECH_1 PF00378.20 KFY03851.1 - 3.3e-25 88.8 0.0 4.2e-25 88.5 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KFY03851.1 - 9.8e-10 38.4 0.0 1.3e-09 38.0 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase DUF3533 PF12051.8 KFY03852.1 - 8.1e-92 308.0 13.3 1.2e-91 307.5 13.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3533) Isochorismatase PF00857.20 KFY03853.1 - 1.9e-40 138.9 0.0 2.1e-40 138.7 0.0 1.0 1 0 0 1 1 1 1 Isochorismatase family DUF1694 PF07997.11 KFY03853.1 - 0.031 14.3 0.0 0.96 9.6 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1694) Ribonuclease_T2 PF00445.18 KFY03853.1 - 0.13 12.5 2.1 0.32 11.2 0.7 1.9 2 0 0 2 2 2 0 Ribonuclease T2 family GFA PF04828.14 KFY03854.1 - 4e-20 72.0 0.0 5.5e-20 71.5 0.0 1.2 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme zf-NADH-PPase PF09297.11 KFY03854.1 - 0.031 13.9 0.4 0.031 13.9 0.4 2.1 2 0 0 2 2 2 0 NADH pyrophosphatase zinc ribbon domain NOB1_Zn_bind PF08772.11 KFY03854.1 - 0.06 13.5 0.0 0.13 12.5 0.0 1.5 1 0 0 1 1 1 0 Nin one binding (NOB1) Zn-ribbon like NmrA PF05368.13 KFY03856.1 - 1.7e-33 116.2 0.0 4.1e-33 114.9 0.0 1.6 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KFY03856.1 - 3.2e-10 40.2 0.1 4.7e-10 39.6 0.1 1.3 1 0 0 1 1 1 1 NAD(P)H-binding TrkA_N PF02254.18 KFY03856.1 - 0.00031 21.0 0.1 0.00052 20.3 0.1 1.3 1 0 0 1 1 1 1 TrkA-N domain 3Beta_HSD PF01073.19 KFY03856.1 - 0.033 13.2 0.0 0.042 12.9 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Zn_clus PF00172.18 KFY03857.1 - 1.1e-06 28.6 12.3 2e-06 27.8 12.3 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Glyco_hydro_130 PF04041.13 KFY03858.1 - 1.3e-46 159.1 0.0 1.7e-46 158.6 0.0 1.1 1 0 0 1 1 1 1 beta-1,4-mannooligosaccharide phosphorylase Glyco_hydro_43 PF04616.14 KFY03858.1 - 1.2e-10 41.2 1.9 5.4e-05 22.6 0.0 3.9 3 1 1 4 4 4 2 Glycosyl hydrolases family 43 Glyco_hydro_32N PF00251.20 KFY03858.1 - 3.3e-10 40.0 2.1 3e-08 33.6 0.0 2.8 3 0 0 3 3 3 2 Glycosyl hydrolases family 32 N-terminal domain Glyco_hydro_130 PF04041.13 KFY03859.1 - 5.7e-44 150.3 0.0 6.9e-44 150.1 0.0 1.0 1 0 0 1 1 1 1 beta-1,4-mannooligosaccharide phosphorylase Glyco_hydro_32N PF00251.20 KFY03859.1 - 1.7e-08 34.4 0.4 5.1e-06 26.3 0.0 2.8 2 1 0 3 3 3 2 Glycosyl hydrolases family 32 N-terminal domain Glyco_hydro_43 PF04616.14 KFY03859.1 - 2.9e-08 33.4 0.5 1.8e-05 24.2 0.2 3.9 3 1 1 4 4 4 2 Glycosyl hydrolases family 43 Sugar_tr PF00083.24 KFY03860.1 - 6.1e-76 256.1 17.9 7.1e-76 255.9 17.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KFY03860.1 - 5.5e-36 124.2 43.3 1.2e-27 96.8 25.9 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily Glyco_hydro_2 PF00703.21 KFY03861.1 - 3.9e-11 43.6 0.0 8e-11 42.6 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 2 Mannosidase_ig PF17786.1 KFY03861.1 - 1.4e-10 41.7 0.0 3.9e-10 40.2 0.0 1.8 1 0 0 1 1 1 1 Mannosidase Ig/CBM-like domain Zn_clus PF00172.18 KFY03862.1 - 0.00014 21.9 7.8 0.00026 21.1 7.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TauD PF02668.16 KFY03863.1 - 5.9e-18 65.6 0.8 3.6e-16 59.8 0.1 2.1 1 1 1 2 2 2 2 Taurine catabolism dioxygenase TauD, TfdA family AAA_21 PF13304.6 KFY03863.1 - 0.059 13.2 0.0 0.085 12.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system TilS PF09179.11 KFY03863.1 - 0.13 12.8 1.5 0.26 11.8 0.3 2.0 2 0 0 2 2 2 0 TilS substrate binding domain PNK3P PF08645.11 KFY03864.1 - 4e-25 88.4 0.0 9.8e-25 87.1 0.0 1.5 2 0 0 2 2 2 1 Polynucleotide kinase 3 phosphatase AAA_33 PF13671.6 KFY03864.1 - 1.3e-11 44.8 0.0 2.1e-05 24.7 0.0 2.4 1 1 1 2 2 2 2 AAA domain AAA_22 PF13401.6 KFY03864.1 - 0.028 14.7 0.0 0.07 13.4 0.0 1.8 1 1 0 1 1 1 0 AAA domain AAA_17 PF13207.6 KFY03864.1 - 0.05 14.0 0.0 0.096 13.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA PF00004.29 KFY03864.1 - 0.1 13.1 0.0 0.2 12.1 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) SRPRB PF09439.10 KFY03864.1 - 0.2 11.1 0.0 0.58 9.6 0.0 1.8 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit Dynein_light PF01221.18 KFY03876.1 - 1.6e-40 137.3 1.1 1.9e-40 137.1 1.1 1.1 1 0 0 1 1 1 1 Dynein light chain type 1 Imm48 PF15574.6 KFY03876.1 - 0.043 13.6 0.1 0.071 12.9 0.1 1.3 1 1 0 1 1 1 0 Immunity protein 48 RRM_1 PF00076.22 KFY03877.1 - 1.4e-74 245.9 1.1 2e-17 62.7 0.0 5.7 5 0 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KFY03877.1 - 4.1e-11 42.6 0.0 0.011 15.5 0.0 5.0 5 0 0 5 5 5 3 Occluded RNA-recognition motif RRM_5 PF13893.6 KFY03877.1 - 1.3e-06 28.0 0.0 0.023 14.3 0.0 4.0 3 1 1 4 4 4 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 KFY03877.1 - 4.6e-06 26.5 0.2 2.4 8.2 0.0 3.9 4 0 0 4 4 4 3 Nup53/35/40-type RNA recognition motif Limkain-b1 PF11608.8 KFY03877.1 - 1e-05 25.5 0.7 0.086 12.9 0.0 5.2 7 1 0 7 7 7 1 Limkain b1 RRM_3 PF08777.11 KFY03877.1 - 3.1e-05 24.0 2.6 1.7 8.8 0.0 4.0 3 0 0 3 3 3 3 RNA binding motif RRM_7 PF16367.5 KFY03877.1 - 4.7e-05 23.4 0.0 4.6 7.4 0.0 4.6 5 0 0 5 5 5 2 RNA recognition motif Smg4_UPF3 PF03467.15 KFY03877.1 - 0.017 15.2 0.9 0.18 11.8 0.7 3.0 3 1 0 3 3 3 0 Smg-4/UPF3 family RRM_Rrp7 PF17799.1 KFY03877.1 - 0.047 13.5 0.1 35 4.1 0.0 3.8 4 0 0 4 4 4 0 Rrp7 RRM-like N-terminal domain TEA PF01285.18 KFY03878.1 - 1.4e-24 85.9 0.0 3.3e-24 84.8 0.0 1.7 1 0 0 1 1 1 1 TEA/ATTS domain Codanin-1_C PF15296.6 KFY03878.1 - 0.67 10.0 2.9 0.49 10.5 0.7 1.9 2 0 0 2 2 2 0 Codanin-1 C-terminus NAD_binding_1 PF00175.21 KFY03879.1 - 3.7e-29 101.5 0.0 6.6e-29 100.7 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 KFY03879.1 - 1.1e-22 80.2 0.0 1.9e-22 79.4 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.12 KFY03879.1 - 1.3e-09 38.4 0.0 5.9e-05 23.2 0.0 2.4 1 1 1 2 2 2 2 Ferric reductase NAD binding domain FAD_binding_9 PF08021.11 KFY03879.1 - 0.048 13.9 0.0 0.12 12.6 0.0 1.6 2 0 0 2 2 2 0 Siderophore-interacting FAD-binding domain Fungal_trans PF04082.18 KFY03880.1 - 7.7e-11 41.5 0.0 1.2e-10 40.9 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KFY03880.1 - 1.5e-09 37.8 11.1 2.5e-09 37.1 11.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain YpM PF09144.10 KFY03880.1 - 0.12 12.5 0.0 0.22 11.7 0.0 1.3 1 0 0 1 1 1 0 Yersinia pseudo-tuberculosis mitogen DUF3395 PF11875.8 KFY03881.1 - 1.8e-28 99.4 0.8 1.2e-27 96.8 0.8 2.2 1 1 0 1 1 1 1 Domain of unknown function (DUF3395) DnaJ PF00226.31 KFY03881.1 - 6e-15 55.1 0.5 1.5e-14 53.8 0.5 1.7 1 0 0 1 1 1 1 DnaJ domain Tom22 PF04281.13 KFY03881.1 - 1 9.2 5.3 2.2 8.1 0.0 2.4 2 0 0 2 2 2 0 Mitochondrial import receptor subunit Tom22 CENP-B_dimeris PF09026.10 KFY03881.1 - 1.3 9.4 9.5 7.5 7.0 9.3 2.1 2 0 0 2 2 2 0 Centromere protein B dimerisation domain Dicty_REP PF05086.12 KFY03881.1 - 4.8 5.0 5.7 6.7 4.6 5.7 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein NOA36 PF06524.12 KFY03881.1 - 5 6.4 6.6 8.2 5.7 6.6 1.2 1 0 0 1 1 1 0 NOA36 protein FRG1 PF06229.12 KFY03882.1 - 9.5e-50 169.0 0.1 1.4e-49 168.4 0.1 1.3 1 0 0 1 1 1 1 FRG1-like domain Fascin PF06268.13 KFY03882.1 - 0.036 14.3 0.0 0.093 13.0 0.0 1.7 2 0 0 2 2 2 0 Fascin domain 2OG-FeII_Oxy PF03171.20 KFY03883.1 - 0.019 15.4 0.1 0.07 13.6 0.1 2.0 1 1 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily DUF1656 PF07869.12 KFY03884.1 - 0.17 11.9 1.8 0.36 10.9 1.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1656) DUF1100 PF06500.11 KFY03885.1 - 6.7e-10 38.3 0.0 1.6e-09 37.1 0.0 1.5 2 0 0 2 2 2 1 Alpha/beta hydrolase of unknown function (DUF1100) Abhydrolase_6 PF12697.7 KFY03885.1 - 3e-08 34.5 0.4 1e-06 29.5 0.3 2.4 1 1 1 2 2 2 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 KFY03885.1 - 3.2e-06 26.8 0.1 1.4e-05 24.6 0.0 2.1 2 0 0 2 2 2 1 Prolyl oligopeptidase family Esterase PF00756.20 KFY03885.1 - 0.00069 19.3 0.0 0.0013 18.4 0.0 1.4 1 0 0 1 1 1 1 Putative esterase Hydrolase_4 PF12146.8 KFY03885.1 - 0.045 13.0 0.2 0.36 10.0 0.1 2.4 3 0 0 3 3 3 0 Serine aminopeptidase, S33 PAF-AH_p_II PF03403.13 KFY03885.1 - 0.2 10.1 0.0 0.55 8.7 0.0 1.6 2 0 0 2 2 2 0 Platelet-activating factor acetylhydrolase, isoform II ADH_zinc_N PF00107.26 KFY03886.1 - 2.5e-12 46.9 0.0 5.2e-11 42.6 0.0 2.3 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KFY03886.1 - 0.00023 21.0 0.0 0.0091 15.9 0.0 2.4 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 KFY03886.1 - 0.00066 20.7 0.0 0.0017 19.4 0.0 1.7 1 1 0 1 1 1 1 Zinc-binding dehydrogenase MFS_1 PF07690.16 KFY03888.1 - 1.2e-33 116.5 40.8 1.8e-29 102.8 23.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 KFY03888.1 - 0.0017 17.7 2.0 0.0017 17.7 2.0 2.5 2 1 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB VIT1 PF01988.19 KFY03888.1 - 3.5 7.5 7.3 0.21 11.5 0.7 2.4 2 1 0 2 2 2 0 VIT family Abhydrolase_3 PF07859.13 KFY03889.1 - 8.8e-48 162.9 0.0 1.2e-47 162.5 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 KFY03889.1 - 6.3e-05 22.0 0.1 0.00018 20.5 0.1 1.7 1 1 0 1 1 1 1 Carboxylesterase family PsbU PF06514.11 KFY03889.1 - 0.14 12.1 0.1 0.39 10.7 0.1 1.7 2 0 0 2 2 2 0 Photosystem II 12 kDa extrinsic protein (PsbU) DUF2808 PF10989.8 KFY03889.1 - 0.19 11.7 0.2 0.3 11.1 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2808) FMO-like PF00743.19 KFY03890.1 - 5.7e-41 140.5 0.0 9.6e-21 73.8 0.0 3.1 3 0 0 3 3 3 3 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 KFY03890.1 - 9.6e-18 64.5 0.1 5e-14 52.2 0.0 2.6 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KFY03890.1 - 5.1e-14 52.2 0.1 4.4e-13 49.1 0.1 2.3 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KFY03890.1 - 2.6e-08 34.3 0.4 0.00035 21.1 0.2 3.5 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KFY03890.1 - 3.6e-08 33.4 1.8 0.053 13.1 1.5 3.2 3 0 0 3 3 3 3 FAD dependent oxidoreductase Amino_oxidase PF01593.24 KFY03890.1 - 5.6e-08 32.5 0.1 0.00082 18.8 0.0 3.0 3 0 0 3 3 3 2 Flavin containing amine oxidoreductase NAD_binding_9 PF13454.6 KFY03890.1 - 1.7e-07 31.4 1.7 1.1e-05 25.5 1.1 3.4 3 1 0 3 3 3 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 KFY03890.1 - 2.4e-06 27.7 0.0 9.3e-06 25.8 0.0 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.6 KFY03890.1 - 2.5e-05 23.6 1.5 0.00011 21.5 0.0 2.3 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Thi4 PF01946.17 KFY03890.1 - 0.00052 19.3 0.6 0.001 18.3 0.6 1.5 1 0 0 1 1 1 1 Thi4 family AlaDh_PNT_C PF01262.21 KFY03890.1 - 0.0031 16.8 1.4 0.25 10.6 1.1 3.0 3 0 0 3 3 3 1 Alanine dehydrogenase/PNT, C-terminal domain Shikimate_DH PF01488.20 KFY03890.1 - 0.0051 16.9 0.3 2.2 8.3 0.3 2.4 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase HI0933_like PF03486.14 KFY03890.1 - 0.0093 14.7 1.0 0.0093 14.7 1.0 1.5 2 0 0 2 2 2 1 HI0933-like protein FAD_oxidored PF12831.7 KFY03890.1 - 0.0099 15.3 0.1 0.087 12.2 0.0 2.2 3 0 0 3 3 3 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 KFY03890.1 - 0.014 14.6 0.8 0.037 13.3 0.8 1.6 1 0 0 1 1 1 0 FAD binding domain 2-Hacid_dh_C PF02826.19 KFY03890.1 - 0.12 11.7 0.1 18 4.6 0.0 2.3 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_2 PF03446.15 KFY03890.1 - 0.17 12.0 0.1 1.2 9.2 0.1 2.2 2 0 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase 3HCDH_N PF02737.18 KFY03890.1 - 0.21 11.4 0.5 0.46 10.3 0.5 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_binding_2 PF00890.24 KFY03890.1 - 0.29 10.2 1.1 0.58 9.2 1.1 1.5 1 0 0 1 1 1 0 FAD binding domain ApbA PF02558.16 KFY03890.1 - 0.76 9.4 2.3 18 5.0 0.7 2.7 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA p450 PF00067.22 KFY03891.1 - 1.6e-62 211.8 0.0 2e-62 211.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 AdoMet_MTase PF07757.13 KFY03901.1 - 0.00017 21.9 0.0 0.00021 21.6 0.0 1.1 1 0 0 1 1 1 1 Predicted AdoMet-dependent methyltransferase Methyltransf_31 PF13847.6 KFY03901.1 - 0.0065 16.3 0.0 0.0099 15.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MetW PF07021.12 KFY03901.1 - 0.12 12.0 0.0 0.15 11.6 0.0 1.2 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW HEAT PF02985.22 KFY03902.1 - 8.7e-37 122.0 19.6 0.015 15.5 0.1 13.2 14 0 0 14 14 14 11 HEAT repeat HEAT_2 PF13646.6 KFY03902.1 - 6e-35 119.5 7.4 1.4e-11 44.6 0.0 8.3 4 2 4 8 8 8 8 HEAT repeats HEAT_EZ PF13513.6 KFY03902.1 - 7.2e-13 48.7 8.8 0.0082 16.6 0.0 8.6 8 2 2 10 10 10 3 HEAT-like repeat Vac14_Fab1_bd PF12755.7 KFY03902.1 - 2.7e-12 47.1 3.6 0.007 16.9 0.1 7.6 5 2 4 9 9 8 1 Vacuolar 14 Fab1-binding region Cnd1 PF12717.7 KFY03902.1 - 1.6e-10 41.2 11.4 0.0014 18.7 0.2 6.1 4 1 3 7 7 7 3 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.20 KFY03902.1 - 3.5e-08 32.5 7.2 3.1e-05 22.7 1.3 3.7 2 1 1 4 4 4 2 Adaptin N terminal region RTP1_C1 PF10363.9 KFY03902.1 - 5.9e-06 26.4 4.2 1.5 9.0 0.1 5.2 4 1 1 5 5 5 1 Required for nuclear transport of RNA pol II C-terminus 1 CLASP_N PF12348.8 KFY03902.1 - 0.00017 21.2 4.3 3 7.4 0.1 4.5 2 2 3 5 5 5 2 CLASP N terminal Proteasom_PSMB PF10508.9 KFY03902.1 - 0.026 13.0 4.6 0.45 8.9 0.0 2.4 2 1 0 2 2 2 0 Proteasome non-ATPase 26S subunit M11L PF11099.8 KFY03902.1 - 0.04 14.2 0.6 15 5.8 0.0 3.6 2 1 2 4 4 4 0 Apoptosis regulator M11L like Ecm29 PF13001.7 KFY03902.1 - 0.065 11.9 4.9 9.5 4.8 0.0 4.2 4 1 1 5 5 5 0 Proteasome stabiliser IFRD PF05004.13 KFY03902.1 - 0.12 11.5 0.3 0.77 8.8 0.2 2.6 1 1 1 2 2 2 0 Interferon-related developmental regulator (IFRD) Arm PF00514.23 KFY03902.1 - 0.24 11.5 4.7 3.3 7.9 0.0 3.9 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat tRNA_synthFbeta PF17759.1 KFY03903.1 - 2.9e-42 144.5 0.0 4.2e-42 144.0 0.0 1.3 1 0 0 1 1 1 1 Phenylalanyl tRNA synthetase beta chain CLM domain PhetRS_B1 PF18262.1 KFY03903.1 - 7.2e-33 112.7 0.4 1.3e-31 108.7 0.1 2.4 2 0 0 2 2 2 1 Phe-tRNA synthetase beta subunit B1 domain B3_4 PF03483.17 KFY03903.1 - 6.1e-26 91.1 0.0 1e-25 90.4 0.0 1.4 1 0 0 1 1 1 1 B3/4 domain B5 PF03484.15 KFY03903.1 - 6.6e-18 64.8 0.0 1.9e-14 53.7 0.0 2.6 2 0 0 2 2 2 2 tRNA synthetase B5 domain Herpes_V23 PF01802.17 KFY03903.1 - 0.017 14.5 0.0 0.029 13.8 0.0 1.3 1 0 0 1 1 1 0 Herpesvirus VP23 like capsid protein Myotub-related PF06602.14 KFY03904.1 - 5.2e-148 492.7 0.0 6.4e-148 492.4 0.0 1.1 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain Ribosomal_S3_C PF00189.20 KFY03905.1 - 8.7e-25 87.1 0.2 5.5e-24 84.5 0.1 2.2 2 0 0 2 2 2 1 Ribosomal protein S3, C-terminal domain KH_2 PF07650.17 KFY03905.1 - 6.4e-12 45.1 0.1 1.1e-11 44.3 0.1 1.4 1 0 0 1 1 1 1 KH domain UN_NPL4 PF11543.8 KFY03905.1 - 0.1 13.1 0.0 0.2 12.2 0.0 1.5 1 0 0 1 1 1 0 Nuclear pore localisation protein NPL4 Coilin_N PF15862.5 KFY03905.1 - 0.11 12.3 0.1 0.33 10.8 0.0 1.7 2 0 0 2 2 2 0 Coilin N-terminus Mg_trans_NIPA PF05653.14 KFY03906.1 - 9.5e-108 359.8 15.8 1.1e-107 359.5 15.8 1.0 1 0 0 1 1 1 1 Magnesium transporter NIPA EamA PF00892.20 KFY03906.1 - 0.00031 20.9 6.7 0.00031 20.9 6.7 3.3 3 0 0 3 3 3 2 EamA-like transporter family DUF2420 PF10336.9 KFY03907.1 - 6.5e-16 58.3 0.0 1.1e-15 57.5 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2420) Adap_comp_sub PF00928.21 KFY03908.1 - 7.2e-19 68.2 0.7 1e-18 67.7 0.7 1.2 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 KFY03908.1 - 1.8e-08 34.4 0.1 3.4e-08 33.5 0.1 1.5 1 0 0 1 1 1 1 Clathrin adaptor complex small chain RPM2 PF08579.11 KFY03908.1 - 0.0021 18.5 0.3 0.0051 17.2 0.3 1.7 1 0 0 1 1 1 1 Mitochondrial ribonuclease P subunit (RPM2) Imm1 PF14430.6 KFY03908.1 - 0.12 13.1 0.0 0.29 11.8 0.0 1.7 1 0 0 1 1 1 0 Immunity protein Imm1 ANAPC4 PF12896.7 KFY03909.1 - 2.9e-57 193.5 0.0 4.5e-57 192.9 0.0 1.2 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 4 ANAPC4_WD40 PF12894.7 KFY03909.1 - 4e-25 87.9 0.4 7.4e-25 87.1 0.1 1.6 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KFY03909.1 - 0.00059 20.6 0.0 2.6 9.0 0.0 3.9 3 0 0 3 3 3 2 WD domain, G-beta repeat TetR_C_33 PF13305.6 KFY03909.1 - 0.02 15.6 1.3 0.99 10.2 0.3 3.3 3 1 0 3 3 3 0 Tetracyclin repressor-like, C-terminal domain IKI3 PF04762.12 KFY03909.1 - 0.11 10.5 0.0 0.16 9.9 0.0 1.1 1 0 0 1 1 1 0 IKI3 family TRP PF06011.12 KFY03917.1 - 3.6e-166 553.1 30.9 4.4e-166 552.8 30.9 1.1 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.6 KFY03917.1 - 1.1e-41 142.4 1.0 2.5e-41 141.3 1.0 1.6 1 0 0 1 1 1 1 ML-like domain Trp_oprn_chp PF09534.10 KFY03917.1 - 0.45 10.3 9.0 2.1 8.1 3.2 3.1 2 1 1 3 3 3 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) Ac76 PF05814.11 KFY03917.1 - 0.53 10.3 6.3 1.5 8.9 0.6 3.2 3 1 0 3 3 3 0 Orf76 (Ac76) SHR-BD PF06650.12 KFY03919.1 - 7.2e-96 320.7 0.0 7.4e-94 314.1 0.0 2.9 2 0 0 2 2 2 1 SHR-binding domain of vacuolar-sorting associated protein 13 VPS13_mid_rpt PF16910.5 KFY03919.1 - 3.1e-93 311.6 6.0 2.1e-90 302.3 0.2 4.7 5 0 0 5 5 5 2 Repeating coiled region of VPS13 VPS13 PF16908.5 KFY03919.1 - 6e-84 281.5 0.0 3.6e-82 275.7 0.0 3.4 5 0 0 5 5 5 1 Vacuolar sorting-associated protein 13, N-terminal VPS13_C PF16909.5 KFY03919.1 - 3.1e-72 242.1 2.0 3.6e-71 238.6 0.8 2.8 2 0 0 2 2 2 1 Vacuolar-sorting-associated 13 protein C-terminal Chorein_N PF12624.7 KFY03919.1 - 2.8e-40 137.1 0.0 8.6e-40 135.5 0.0 2.0 1 0 0 1 1 1 1 N-terminal region of Chorein or VPS13 DUF3429 PF11911.8 KFY03921.1 - 1.4e-42 145.4 9.2 1.8e-42 145.0 9.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3429) Methyltransf_23 PF13489.6 KFY03926.1 - 3.3e-13 49.8 0.0 5.7e-13 49.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KFY03926.1 - 3.9e-09 37.0 0.0 7.7e-09 36.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KFY03926.1 - 5.4e-08 33.4 0.0 1.6e-07 32.0 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KFY03926.1 - 6.1e-08 32.6 0.0 3e-07 30.3 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KFY03926.1 - 3.1e-05 24.6 0.0 0.0001 23.0 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KFY03926.1 - 0.0022 17.3 0.0 0.011 15.1 0.0 1.9 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family PEHE PF15275.6 KFY03926.1 - 0.0074 16.9 0.2 0.016 15.8 0.2 1.6 1 0 0 1 1 1 1 PEHE domain PRONE PF03759.13 KFY03926.1 - 0.13 11.0 0.0 0.21 10.4 0.0 1.2 1 0 0 1 1 1 0 PRONE (Plant-specific Rop nucleotide exchanger) CP2 PF04516.15 KFY03934.1 - 1.6e-67 227.2 0.0 2.4e-67 226.6 0.0 1.2 1 0 0 1 1 1 1 CP2 transcription factor Fungal_trans PF04082.18 KFY03936.1 - 3.6e-09 36.1 0.4 5.3e-09 35.5 0.4 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-HC5HC2H_2 PF13832.6 KFY03936.1 - 0.7 10.1 4.9 5.1 7.3 0.1 2.4 2 0 0 2 2 2 0 PHD-zinc-finger like domain Zn_clus PF00172.18 KFY03937.1 - 2.5e-09 37.1 12.7 4.7e-09 36.2 12.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KFY03937.1 - 4.6e-05 22.6 0.0 0.0001 21.4 0.0 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Pneumo_phosprot PF02478.16 KFY03938.1 - 0.00091 18.8 0.1 0.0013 18.4 0.1 1.1 1 0 0 1 1 1 1 Pneumovirus phosphoprotein Longin PF13774.6 KFY03943.1 - 1.4e-24 85.9 0.2 2.6e-24 85.1 0.2 1.5 1 0 0 1 1 1 1 Regulated-SNARE-like domain Synaptobrevin PF00957.21 KFY03943.1 - 2e-15 56.3 0.0 4.5e-15 55.2 0.0 1.6 1 0 0 1 1 1 1 Synaptobrevin DUF760 PF05542.11 KFY03943.1 - 0.0087 16.4 0.2 0.096 13.1 0.1 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF760) ASXH PF13919.6 KFY03944.1 - 1.1e-31 109.7 0.7 2e-31 108.8 0.7 1.4 1 0 0 1 1 1 1 Asx homology domain RAMA PF18755.1 KFY03944.1 - 0.0092 16.4 0.0 6.7 7.2 0.0 2.8 2 0 0 2 2 2 2 Restriction Enzyme Adenine Methylase Associated Glyco_hydro_63 PF03200.16 KFY03945.1 - 1.8e-175 584.5 2.5 9.9e-175 582.0 0.2 2.5 2 1 0 2 2 2 1 Glycosyl hydrolase family 63 C-terminal domain Glyco_hydro_63N PF16923.5 KFY03945.1 - 4.2e-90 301.8 0.5 1.3e-89 300.2 0.0 1.9 2 0 0 2 2 2 1 Glycosyl hydrolase family 63 N-terminal domain Trehalase PF01204.18 KFY03945.1 - 0.0045 15.9 0.1 0.01 14.7 0.1 1.6 1 1 0 1 1 1 1 Trehalase GDE_C PF06202.14 KFY03945.1 - 0.038 12.9 0.0 0.069 12.1 0.0 1.3 1 0 0 1 1 1 0 Amylo-alpha-1,6-glucosidase SNRNP27 PF08648.12 KFY03946.1 - 5.5e-28 96.8 1.4 1.3e-27 95.6 1.4 1.6 1 0 0 1 1 1 1 U4/U6.U5 small nuclear ribonucleoproteins Elong_Iki1 PF10483.9 KFY03947.1 - 3.3e-105 351.8 0.0 3.8e-105 351.6 0.0 1.0 1 0 0 1 1 1 1 Elongator subunit Iki1 Mso1_Sec1_bdg PF14475.6 KFY03948.1 - 9e-21 73.2 0.0 1.9e-20 72.2 0.0 1.6 1 0 0 1 1 1 1 Sec1-binding region of Mso1 Ribosomal_L28e PF01778.17 KFY03949.1 - 1.4e-39 135.4 1.7 2.5e-39 134.6 1.7 1.4 1 0 0 1 1 1 1 Ribosomal L28e protein family Mak16 PF04874.14 KFY03949.1 - 6.5e-32 110.1 10.9 6.5e-32 110.1 10.9 2.4 2 0 0 2 2 2 1 Mak16 protein C-terminal region BUD22 PF09073.10 KFY03949.1 - 1.4e-06 27.9 11.1 1.8e-06 27.6 11.1 1.1 1 0 0 1 1 1 1 BUD22 PYC_OADA PF02436.18 KFY03949.1 - 0.03 14.1 0.6 0.051 13.3 0.6 1.4 1 0 0 1 1 1 0 Conserved carboxylase domain TFIIF_alpha PF05793.12 KFY03949.1 - 1.2 7.7 22.6 1.4 7.5 22.6 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Drc1-Sld2 PF11719.8 KFY03949.1 - 1.4 8.4 11.3 2.2 7.8 11.3 1.4 1 0 0 1 1 1 0 DNA replication and checkpoint protein MnmE_helical PF12631.7 KFY03950.1 - 3.8e-39 135.0 0.3 4.8e-39 134.7 0.3 1.1 1 0 0 1 1 1 1 MnmE helical domain TrmE_N PF10396.9 KFY03950.1 - 1.2e-29 103.0 0.0 2.6e-29 101.9 0.0 1.6 1 0 0 1 1 1 1 GTP-binding protein TrmE N-terminus MMR_HSR1 PF01926.23 KFY03950.1 - 1.7e-18 66.8 0.0 3.1e-18 65.9 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.23 KFY03950.1 - 1.6e-05 25.0 0.0 3.2e-05 24.1 0.0 1.5 1 0 0 1 1 1 1 Dynamin family FeoB_N PF02421.18 KFY03950.1 - 0.00038 20.0 0.0 0.00064 19.3 0.0 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B AAA_24 PF13479.6 KFY03950.1 - 0.02 14.6 0.0 0.038 13.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 KFY03950.1 - 0.028 14.3 0.0 0.31 10.9 0.0 2.4 2 0 0 2 2 2 0 RsgA GTPase Glyco_hydro_3_C PF01915.22 KFY03950.1 - 0.036 14.0 0.2 0.087 12.8 0.1 1.7 1 1 1 2 2 2 0 Glycosyl hydrolase family 3 C-terminal domain ABC_tran PF00005.27 KFY03950.1 - 0.097 13.2 0.0 0.27 11.7 0.0 1.8 2 0 0 2 2 2 0 ABC transporter GTP_EFTU PF00009.27 KFY03950.1 - 0.098 12.2 0.0 1.7 8.1 0.0 2.3 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain Roc PF08477.13 KFY03950.1 - 0.16 12.2 0.0 0.52 10.6 0.0 1.9 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Ribosomal_L28 PF00830.19 KFY03951.1 - 0.1 12.8 0.3 0.12 12.6 0.3 1.4 1 1 0 1 1 1 0 Ribosomal L28 family zf-C2H2 PF00096.26 KFY03952.1 - 0.023 15.1 0.0 0.043 14.3 0.0 1.5 1 0 0 1 1 1 0 Zinc finger, C2H2 type Med6 PF04934.14 KFY03953.1 - 4.9e-41 139.7 0.0 1e-40 138.6 0.0 1.6 1 0 0 1 1 1 1 MED6 mediator sub complex component RabGAP-TBC PF00566.18 KFY03953.1 - 4.3e-39 134.4 0.3 8.5e-39 133.4 0.3 1.5 1 0 0 1 1 1 1 Rab-GTPase-TBC domain MMtag PF10159.9 KFY03953.1 - 2.3e-30 104.7 3.2 6.4e-30 103.3 3.2 1.9 1 0 0 1 1 1 1 Multiple myeloma tumor-associated PH_RBD PF12068.8 KFY03953.1 - 3.1e-05 23.5 0.0 0.0003 20.3 0.0 2.4 2 1 0 2 2 2 1 Rab-binding domain (RBD) Egh16-like PF11327.8 KFY03954.1 - 1.9e-16 61.0 0.1 2.4e-16 60.7 0.1 1.1 1 0 0 1 1 1 1 Egh16-like virulence factor F-box-like PF12937.7 KFY03955.1 - 7.8e-08 32.1 0.1 2e-07 30.8 0.1 1.7 1 0 0 1 1 1 1 F-box-like STAS PF01740.21 KFY03955.1 - 0.00012 21.7 0.0 0.00024 20.7 0.0 1.4 1 0 0 1 1 1 1 STAS domain F-box PF00646.33 KFY03955.1 - 0.012 15.4 0.3 0.034 14.0 0.0 1.9 2 0 0 2 2 2 0 F-box domain Podoplanin PF05808.11 KFY03956.1 - 0.0004 20.5 0.2 0.00088 19.4 0.2 1.5 1 0 0 1 1 1 1 Podoplanin DUF4690 PF15756.5 KFY03956.1 - 0.0065 17.0 3.7 0.0093 16.5 0.9 2.4 2 1 0 2 2 2 1 Small Novel Rich in Cartilage EphA2_TM PF14575.6 KFY03956.1 - 0.013 16.3 0.0 0.033 15.1 0.0 1.6 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DUF3290 PF11694.8 KFY03956.1 - 0.023 14.7 0.4 0.042 13.8 0.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3290) Pox_A14 PF05767.12 KFY03956.1 - 0.051 13.7 0.0 0.12 12.6 0.0 1.5 1 0 0 1 1 1 0 Poxvirus virion envelope protein A14 RIFIN PF02009.16 KFY03956.1 - 0.056 13.3 0.0 0.086 12.7 0.0 1.2 1 0 0 1 1 1 0 Rifin DUF2207 PF09972.9 KFY03956.1 - 0.099 11.4 0.0 0.15 10.8 0.0 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Yip1 PF04893.17 KFY03956.1 - 0.2 11.4 0.1 0.2 11.4 0.1 1.7 2 0 0 2 2 2 0 Yip1 domain Stevor PF17410.2 KFY03956.1 - 0.2 11.2 0.0 0.33 10.5 0.0 1.4 1 0 0 1 1 1 0 Subtelomeric Variable Open Reading frame SKG6 PF08693.10 KFY03956.1 - 5.2 6.6 13.0 0.093 12.2 6.1 1.7 2 0 0 2 2 2 0 Transmembrane alpha-helix domain NDUF_B7 PF05676.13 KFY03957.1 - 9.4e-28 95.7 5.8 1.1e-27 95.5 5.8 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) Ank_2 PF12796.7 KFY03958.1 - 5.3e-12 46.2 0.2 0.00033 21.2 0.8 2.9 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 KFY03958.1 - 1.4e-10 41.1 2.2 0.027 14.9 0.0 4.3 3 1 1 4 4 4 3 Ankyrin repeat Ank_4 PF13637.6 KFY03958.1 - 1.7e-09 38.0 2.2 0.0003 21.3 0.0 3.4 1 1 2 3 3 3 2 Ankyrin repeats (many copies) KilA-N PF04383.13 KFY03958.1 - 9.4e-08 31.9 0.0 3.2e-07 30.2 0.0 1.8 1 1 0 1 1 1 1 KilA-N domain Ank_3 PF13606.6 KFY03958.1 - 4.6e-07 29.6 0.6 0.039 14.5 0.0 4.8 4 0 0 4 4 4 1 Ankyrin repeat Ank_5 PF13857.6 KFY03958.1 - 3.1e-06 27.3 1.1 0.11 12.9 0.0 3.6 3 0 0 3 3 3 2 Ankyrin repeats (many copies) MIS13 PF08202.11 KFY03959.1 - 5.6e-44 150.6 0.0 1.6e-43 149.2 0.0 1.7 2 0 0 2 2 2 1 Mis12-Mtw1 protein family WD40_alt PF14077.6 KFY03959.1 - 0.19 11.6 0.2 0.36 10.7 0.2 1.4 1 0 0 1 1 1 0 Alternative WD40 repeat motif DUF966 PF06136.13 KFY03959.1 - 3 7.5 7.6 4.3 6.9 7.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF966) Nucleoporin_N PF08801.11 KFY03960.1 - 4.1e-48 164.2 0.0 5.4e-48 163.8 0.0 1.1 1 0 0 1 1 1 1 Nup133 N terminal like Sedlin_N PF04628.13 KFY03961.1 - 4.4e-11 43.0 0.0 6.9e-11 42.4 0.0 1.3 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region Zn_clus PF00172.18 KFY03962.1 - 0.00066 19.8 21.9 0.1 12.7 7.6 3.8 2 1 1 3 3 3 3 Fungal Zn(2)-Cys(6) binuclear cluster domain TRAP_alpha PF03896.16 KFY03962.1 - 0.39 9.9 2.5 1.3 8.2 2.5 1.8 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit DUF4666 PF15697.5 KFY03962.1 - 3.4 8.4 9.8 0.2 12.4 0.8 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4666) Glyco_hydro_115 PF15979.5 KFY03963.1 - 1e-134 449.3 2.1 1.4e-134 448.9 2.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 115 GH115_C PF17829.1 KFY03963.1 - 1e-59 201.2 0.0 2.9e-59 199.7 0.0 1.8 2 0 0 2 2 2 1 Gylcosyl hydrolase family 115 C-terminal domain DUF3328 PF11807.8 KFY03964.1 - 1.2e-11 44.8 0.0 5.5e-11 42.7 0.0 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF3328) F-box-like PF12937.7 KFY03964.1 - 0.97 9.4 4.7 24 4.9 1.4 2.8 2 0 0 2 2 2 0 F-box-like Sugar_tr PF00083.24 KFY03966.1 - 1.1e-84 284.9 20.4 1.3e-84 284.7 20.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KFY03966.1 - 4.4e-31 108.1 26.0 6.5e-28 97.7 18.7 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 KFY03966.1 - 4.9e-06 25.4 1.6 4.9e-06 25.4 1.6 2.6 2 1 0 2 2 2 1 MFS/sugar transport protein MFS_4 PF06779.14 KFY03966.1 - 5.2e-05 22.7 0.5 5.2e-05 22.7 0.5 1.8 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB TRI12 PF06609.13 KFY03966.1 - 0.0014 17.1 4.4 0.0039 15.7 1.9 2.0 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) YrhK PF14145.6 KFY03966.1 - 0.075 12.9 0.3 0.075 12.9 0.3 2.9 3 0 0 3 3 3 0 YrhK-like protein Fungal_trans_2 PF11951.8 KFY03967.1 - 3.8e-21 75.3 0.0 6.6e-21 74.6 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain FAD_binding_4 PF01565.23 KFY03967.1 - 1e-19 70.6 0.3 2.1e-19 69.6 0.3 1.6 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 KFY03967.1 - 1.6e-06 28.1 1.4 3.7e-06 26.9 1.4 1.5 1 0 0 1 1 1 1 Berberine and berberine like Cupin_2 PF07883.11 KFY03968.1 - 1.4e-10 40.7 0.0 2.7e-10 39.8 0.0 1.5 1 0 0 1 1 1 1 Cupin domain Cupin_1 PF00190.22 KFY03968.1 - 1.3e-06 28.1 0.0 1.4e-06 28.0 0.0 1.2 1 0 0 1 1 1 1 Cupin 3-HAO PF06052.12 KFY03968.1 - 2.4e-05 24.0 0.0 2.8e-05 23.8 0.0 1.1 1 0 0 1 1 1 1 3-hydroxyanthranilic acid dioxygenase Cupin_3 PF05899.12 KFY03968.1 - 7.6e-05 22.3 0.0 0.00012 21.7 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF861) Cupin_4 PF08007.12 KFY03968.1 - 0.0034 16.9 0.0 0.0043 16.6 0.0 1.1 1 0 0 1 1 1 1 Cupin superfamily protein ARD PF03079.14 KFY03968.1 - 0.02 15.1 0.0 0.025 14.7 0.0 1.3 1 0 0 1 1 1 0 ARD/ARD' family Cupin_7 PF12973.7 KFY03968.1 - 0.035 14.0 0.0 2.2 8.3 0.0 2.1 2 0 0 2 2 2 0 ChrR Cupin-like domain Cupin_6 PF12852.7 KFY03968.1 - 0.088 12.5 0.0 0.11 12.3 0.0 1.1 1 0 0 1 1 1 0 Cupin AA_permease PF00324.21 KFY03969.1 - 4.5e-148 493.8 39.3 1.5e-106 356.9 28.5 2.1 2 0 0 2 2 2 2 Amino acid permease AA_permease_2 PF13520.6 KFY03969.1 - 3.2e-42 144.8 39.1 1.9e-31 109.4 29.3 2.0 2 0 0 2 2 2 2 Amino acid permease ClpS PF02617.17 KFY03969.1 - 0.16 11.8 0.0 17 5.2 0.0 2.3 2 0 0 2 2 2 0 ATP-dependent Clp protease adaptor protein ClpS MFS_1 PF07690.16 KFY03970.1 - 2.2e-38 132.1 24.1 2.2e-38 132.1 24.1 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KFY03970.1 - 3.4e-12 46.0 16.4 3.4e-12 46.0 16.4 1.5 1 1 0 1 1 1 1 Sugar (and other) transporter Mito_carr PF00153.27 KFY03978.1 - 2.1e-65 216.7 2.9 4.9e-21 74.4 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Cofilin_ADF PF00241.20 KFY03979.1 - 6.5e-37 126.0 0.1 1.6e-21 76.4 0.0 2.2 2 0 0 2 2 2 2 Cofilin/tropomyosin-type actin-binding protein Med22 PF06179.12 KFY03980.1 - 1.3e-19 70.3 0.1 2e-19 69.7 0.1 1.3 1 0 0 1 1 1 1 Surfeit locus protein 5 subunit 22 of Mediator complex DUF5428 PF17493.2 KFY03980.1 - 0.0038 17.6 0.3 0.0087 16.5 0.3 1.6 1 0 0 1 1 1 1 Family of unknown function (DUF5428) Pkinase PF00069.25 KFY03981.1 - 2.6e-61 207.3 0.0 4.9e-59 199.8 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFY03981.1 - 3.7e-28 98.5 0.0 3.3e-20 72.5 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 KFY03981.1 - 2.2e-07 30.5 0.1 6.6e-07 28.9 0.1 1.8 1 1 1 2 2 2 1 Kinase-like PseudoU_synth_1 PF01416.20 KFY03982.1 - 1.2e-10 41.8 0.0 2.5e-09 37.6 0.0 2.6 2 0 0 2 2 2 1 tRNA pseudouridine synthase DUF2344 PF10105.9 KFY03982.1 - 0.04 13.8 0.4 0.9 9.4 0.0 2.8 3 1 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2344) IBB PF01749.20 KFY03982.1 - 0.76 10.3 5.5 0.2 12.1 0.9 2.5 2 0 0 2 2 2 0 Importin beta binding domain TFIIE_alpha PF02002.17 KFY03983.1 - 6.3e-18 64.6 0.1 1.2e-17 63.7 0.1 1.4 1 0 0 1 1 1 1 TFIIE alpha subunit ILVD_EDD PF00920.21 KFY03984.1 - 1.5e-211 703.6 0.8 1.7e-211 703.3 0.8 1.0 1 0 0 1 1 1 1 Dehydratase family 5_nucleotid_C PF02872.18 KFY03984.1 - 0.021 15.0 0.0 0.12 12.5 0.0 2.2 2 0 0 2 2 2 0 5'-nucleotidase, C-terminal domain Pkinase PF00069.25 KFY03985.1 - 9.6e-46 156.3 0.0 3e-44 151.4 0.0 2.1 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFY03985.1 - 6.4e-28 97.7 0.0 2.5e-27 95.8 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KFY03985.1 - 0.0049 15.7 0.0 0.011 14.6 0.0 1.5 1 0 0 1 1 1 1 Fungal protein kinase Kinesin PF00225.23 KFY03987.1 - 1.3e-105 353.1 1.0 1.3e-105 353.1 1.0 2.6 2 1 1 4 4 4 1 Kinesin motor domain Microtub_bd PF16796.5 KFY03987.1 - 3.7e-56 189.2 0.0 1.3e-55 187.5 0.0 2.0 1 0 0 1 1 1 1 Microtubule binding WEMBL PF05701.11 KFY03987.1 - 0.0024 16.7 37.9 0.0024 16.7 37.9 1.8 2 0 0 2 2 2 1 Weak chloroplast movement under blue light AAA_16 PF13191.6 KFY03987.1 - 0.0031 17.9 0.0 0.0031 17.9 0.0 3.1 2 1 0 2 2 2 1 AAA ATPase domain AAA_24 PF13479.6 KFY03987.1 - 0.088 12.5 1.2 0.14 11.8 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 KFY03987.1 - 0.77 10.0 0.0 0.77 10.0 0.0 3.1 2 1 0 3 3 3 0 AAA domain DUF5082 PF16888.5 KFY03987.1 - 3.9 7.8 37.3 0.061 13.6 11.7 4.2 2 1 2 4 4 4 0 Domain of unknown function (DUF5082) FlaC_arch PF05377.11 KFY03987.1 - 4.1 7.9 12.2 11 6.5 1.2 5.2 3 1 1 4 4 4 0 Flagella accessory protein C (FlaC) Baculo_PEP_C PF04513.12 KFY03987.1 - 5.7 7.0 10.7 0.43 10.6 2.0 2.9 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus HAUS-augmin3 PF14932.6 KFY03988.1 - 0.00012 21.7 12.2 0.00012 21.7 12.2 3.0 3 1 0 3 3 3 1 HAUS augmin-like complex subunit 3 Prominin PF05478.11 KFY03988.1 - 5.2 4.9 12.0 2.8 5.8 4.1 3.0 2 1 1 4 4 4 0 Prominin DUF1295 PF06966.12 KFY03991.1 - 7.1e-15 55.2 0.0 1e-14 54.6 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) ERG4_ERG24 PF01222.17 KFY03991.1 - 6.7e-06 25.1 0.1 1e-05 24.5 0.1 1.3 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family PEMT PF04191.13 KFY03991.1 - 0.00011 22.6 0.4 0.0013 19.1 0.0 2.4 2 1 0 2 2 2 1 Phospholipid methyltransferase NnrU PF07298.11 KFY03991.1 - 0.00025 20.6 0.0 0.00052 19.6 0.0 1.5 1 1 0 1 1 1 1 NnrU protein Steroid_dh PF02544.16 KFY03991.1 - 0.00032 20.7 0.0 0.00055 19.9 0.0 1.6 1 1 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase ICMT PF04140.14 KFY03991.1 - 0.0032 17.8 0.0 0.0086 16.5 0.0 1.8 1 0 0 1 1 1 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family MFS_1 PF07690.16 KFY03992.1 - 1.1e-37 129.8 57.7 2.1e-37 128.9 51.9 3.1 2 1 0 2 2 2 1 Major Facilitator Superfamily P5-ATPase PF12409.8 KFY03992.1 - 0.062 13.4 0.1 0.23 11.6 0.1 1.9 1 0 0 1 1 1 0 P5-type ATPase cation transporter DUF4407 PF14362.6 KFY03992.1 - 0.49 9.7 1.9 0.6 9.4 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) EthD PF07110.11 KFY03993.1 - 1.9e-18 67.4 0.1 2.6e-18 66.9 0.1 1.2 1 0 0 1 1 1 1 EthD domain ketoacyl-synt PF00109.26 KFY03994.1 - 5.6e-78 262.0 0.0 1.1e-77 261.1 0.0 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain SAT PF16073.5 KFY03994.1 - 5.8e-66 222.7 8.5 6.6e-66 222.5 5.2 2.6 3 0 0 3 3 3 1 Starter unit:ACP transacylase in aflatoxin biosynthesis Acyl_transf_1 PF00698.21 KFY03994.1 - 2.2e-39 135.9 0.0 5.5e-39 134.5 0.0 1.6 2 0 0 2 2 2 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 KFY03994.1 - 1.2e-33 115.6 0.5 3.1e-33 114.3 0.5 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain PS-DH PF14765.6 KFY03994.1 - 2.2e-20 73.1 0.0 3.7e-20 72.4 0.0 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase Thioesterase PF00975.20 KFY03994.1 - 7.3e-18 65.5 0.0 2.3e-17 63.9 0.0 1.8 2 0 0 2 2 2 1 Thioesterase domain FAD_binding_3 PF01494.19 KFY03994.1 - 8.6e-17 61.4 1.0 1.3e-15 57.5 1.0 2.2 1 1 0 1 1 1 1 FAD binding domain PP-binding PF00550.25 KFY03994.1 - 1.9e-15 57.0 1.2 7.5e-15 55.0 1.2 2.2 1 0 0 1 1 1 1 Phosphopantetheine attachment site KAsynt_C_assoc PF16197.5 KFY03994.1 - 1e-07 32.4 0.0 2.4e-07 31.2 0.0 1.6 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension Abhydrolase_6 PF12697.7 KFY03994.1 - 0.00013 22.6 1.3 0.00013 22.6 1.3 3.1 2 1 1 3 3 3 1 Alpha/beta hydrolase family NAD_binding_8 PF13450.6 KFY03994.1 - 0.00014 22.0 0.0 0.00075 19.7 0.0 2.3 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thiolase_N PF00108.23 KFY03994.1 - 0.00058 19.3 0.0 0.0013 18.1 0.0 1.5 1 0 0 1 1 1 1 Thiolase, N-terminal domain SE PF08491.10 KFY03994.1 - 0.07 12.2 0.0 1.2 8.1 0.0 2.4 3 0 0 3 3 3 0 Squalene epoxidase ACP_syn_III PF08545.10 KFY03994.1 - 0.11 12.4 0.6 0.75 9.7 0.6 2.5 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Hydrolase_4 PF12146.8 KFY03994.1 - 0.15 11.3 0.0 0.71 9.1 0.0 2.0 2 0 0 2 2 2 0 Serine aminopeptidase, S33 LANC_like PF05147.13 KFY03995.1 - 3.1e-19 68.8 0.0 1.9e-18 66.2 0.0 1.9 1 1 0 1 1 1 1 Lanthionine synthetase C-like protein FAD_binding_4 PF01565.23 KFY03996.1 - 5.4e-22 78.0 3.4 1.2e-21 76.9 3.4 1.6 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 KFY03996.1 - 1.6e-09 37.7 2.7 1.6e-09 37.7 1.0 2.0 2 0 0 2 2 2 1 Berberine and berberine like Acetyltransf_1 PF00583.25 KFY03997.1 - 1.8e-08 34.6 0.0 3.4e-08 33.7 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KFY03997.1 - 8.5e-08 32.2 0.0 1.5e-07 31.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KFY03997.1 - 5.6e-07 29.9 0.0 1.6e-06 28.5 0.0 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KFY03997.1 - 0.0031 17.4 0.0 0.0053 16.7 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.7 KFY03997.1 - 0.077 13.1 0.0 0.14 12.3 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Abhydrolase_6 PF12697.7 KFY03998.1 - 8.5e-14 52.7 12.7 3e-13 50.9 12.7 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KFY03998.1 - 4.9e-09 36.2 0.0 7.6e-09 35.6 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KFY03998.1 - 1.7e-05 24.2 0.0 0.078 12.2 0.1 2.2 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_2 PF02230.16 KFY03998.1 - 0.0059 16.4 0.0 0.22 11.3 0.0 2.1 2 0 0 2 2 2 1 Phospholipase/Carboxylesterase DUF3089 PF11288.8 KFY03998.1 - 0.083 12.4 0.0 0.14 11.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3089) Esterase PF00756.20 KFY03998.1 - 0.12 12.1 0.0 0.16 11.6 0.0 1.2 1 0 0 1 1 1 0 Putative esterase Histone PF00125.24 KFY03999.1 - 2.4e-14 53.8 0.0 4.9e-14 52.8 0.0 1.4 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.6 KFY03999.1 - 0.013 15.8 0.0 0.022 15.2 0.0 1.2 1 0 0 1 1 1 0 CENP-S protein FAM76 PF16046.5 KFY04001.1 - 0.015 14.7 6.2 0.019 14.3 6.2 1.0 1 0 0 1 1 1 0 FAM76 protein TMF_TATA_bd PF12325.8 KFY04001.1 - 7 6.9 13.9 3.9 7.7 11.4 1.7 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding GATA PF00320.27 KFY04002.1 - 0.014 15.0 2.4 0.014 15.0 2.4 6.2 8 1 0 8 8 8 0 GATA zinc finger ArfGap PF01412.18 KFY04002.1 - 1.6 8.8 23.9 8.4 6.5 1.9 5.2 3 2 1 4 4 4 0 Putative GTPase activating protein for Arf NinE PF05322.11 KFY04002.1 - 6.9 6.6 6.7 25 4.9 0.2 3.7 4 0 0 4 4 4 0 NINE Protein Glyco_hydro_18 PF00704.28 KFY04011.1 - 6.4e-89 298.7 7.3 7.9e-89 298.5 7.3 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Na_H_Exchanger PF00999.21 KFY04013.1 - 2.6e-27 95.6 28.0 7.6e-25 87.5 19.2 2.5 3 0 0 3 3 3 2 Sodium/hydrogen exchanger family STE2 PF02116.15 KFY04014.1 - 9.4e-96 320.4 21.5 1.1e-95 320.2 21.5 1.0 1 0 0 1 1 1 1 Fungal pheromone mating factor STE2 GPCR Vps23_core PF09454.10 KFY04017.1 - 3.5e-21 74.9 0.0 8.4e-21 73.7 0.0 1.6 2 0 0 2 2 2 1 Vps23 core domain zf-CHY PF05495.12 KFY04020.1 - 5e-12 46.1 10.0 5e-12 46.1 10.0 3.6 3 0 0 3 3 3 2 CHY zinc finger Cpn60_TCP1 PF00118.24 KFY04021.1 - 1.5e-159 531.8 4.6 1.7e-159 531.6 4.6 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Torus PF16131.5 KFY04022.1 - 0.0096 16.6 36.5 0.23 12.2 0.7 7.1 5 2 2 7 7 7 4 Torus domain ELFV_dehydrog PF00208.21 KFY04026.1 - 1.4e-87 293.4 2.6 1.8e-87 293.1 2.6 1.1 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase ELFV_dehydrog_N PF02812.18 KFY04026.1 - 6.6e-47 158.7 0.0 1.5e-46 157.5 0.0 1.6 1 0 0 1 1 1 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain Qn_am_d_aIV PF09100.10 KFY04026.1 - 0.0087 15.9 0.5 0.024 14.4 0.5 1.8 1 0 0 1 1 1 1 Quinohemoprotein amine dehydrogenase, alpha subunit domain IV NAD_binding_7 PF13241.6 KFY04026.1 - 0.027 14.9 0.0 0.07 13.6 0.0 1.6 1 1 0 1 1 1 0 Putative NAD(P)-binding FMN_dh PF01070.18 KFY04027.1 - 5.9e-63 213.0 2.4 6.7e-63 212.8 2.4 1.0 1 0 0 1 1 1 1 FMN-dependent dehydrogenase NMO PF03060.15 KFY04027.1 - 8.3e-07 28.7 0.9 1.2e-06 28.2 0.9 1.2 1 0 0 1 1 1 1 Nitronate monooxygenase ThiG PF05690.14 KFY04027.1 - 0.00014 21.2 0.1 0.025 13.9 0.2 2.2 2 0 0 2 2 2 2 Thiazole biosynthesis protein ThiG Glu_synthase PF01645.17 KFY04027.1 - 0.00015 21.0 0.6 0.00033 19.9 0.2 1.6 2 0 0 2 2 2 1 Conserved region in glutamate synthase IMPDH PF00478.25 KFY04027.1 - 0.00016 20.8 1.7 0.00035 19.7 1.7 1.6 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain His_biosynth PF00977.21 KFY04027.1 - 0.00019 21.0 0.3 0.012 15.1 0.1 2.1 1 1 0 2 2 2 1 Histidine biosynthesis protein IGPS PF00218.21 KFY04027.1 - 0.0074 15.5 0.2 0.026 13.7 0.2 1.7 1 1 1 2 2 2 1 Indole-3-glycerol phosphate synthase DHO_dh PF01180.21 KFY04027.1 - 0.0094 15.2 0.3 0.039 13.2 0.1 1.8 1 1 1 2 2 2 1 Dihydroorotate dehydrogenase Asparaginase_C PF17763.1 KFY04027.1 - 0.19 12.0 0.6 0.39 10.9 0.3 1.7 1 1 0 1 1 1 0 Glutaminase/Asparaginase C-terminal domain DUF3040 PF11239.8 KFY04035.1 - 0.018 15.3 0.0 0.028 14.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3040) SET PF00856.28 KFY04036.1 - 1.1e-14 55.2 0.1 4.7e-14 53.1 0.1 2.1 2 0 0 2 2 2 1 SET domain TPR_2 PF07719.17 KFY04036.1 - 0.0007 19.5 2.9 0.082 13.1 0.2 4.1 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_6 PF13174.6 KFY04036.1 - 0.0012 19.3 0.6 0.084 13.5 0.0 3.0 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 KFY04036.1 - 0.0067 17.2 3.1 1 10.3 0.1 3.4 4 0 0 4 4 4 1 Tetratricopeptide repeat DUF5003 PF16394.5 KFY04036.1 - 0.016 14.4 0.1 0.028 13.6 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5003) SRP_TPR_like PF17004.5 KFY04036.1 - 0.14 12.2 0.0 0.36 10.8 0.0 1.6 1 0 0 1 1 1 0 Putative TPR-like repeat TPR_1 PF00515.28 KFY04036.1 - 0.55 10.1 3.0 58 3.7 0.0 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat AAA_12 PF13087.6 KFY04037.1 - 1.9e-19 70.1 0.0 4.2e-19 68.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 KFY04037.1 - 3.7e-13 49.9 0.0 1.3e-12 48.1 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 KFY04037.1 - 1.1e-07 31.7 0.0 0.0021 17.8 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.6 KFY04037.1 - 0.0012 19.2 0.1 0.27 11.6 0.0 2.6 2 0 0 2 2 2 1 AAA domain Viral_helicase1 PF01443.18 KFY04037.1 - 0.015 15.1 0.0 8.4 6.0 0.0 3.5 3 0 0 3 3 3 0 Viral (Superfamily 1) RNA helicase NACHT PF05729.12 KFY04037.1 - 0.077 12.9 0.0 0.17 11.8 0.0 1.5 1 0 0 1 1 1 0 NACHT domain Zn_clus PF00172.18 KFY04038.1 - 6.4e-08 32.6 5.7 1.6e-07 31.3 5.7 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 KFY04038.1 - 0.018 13.9 0.1 0.028 13.2 0.1 1.2 1 0 0 1 1 1 0 Fungal specific transcription factor domain Glyco_hydro_8 PF01270.17 KFY04038.1 - 0.12 11.2 0.0 0.18 10.6 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolases family 8 Peptidase_C2 PF00648.21 KFY04046.1 - 2e-32 112.5 0.0 2.8e-32 111.9 0.0 1.2 1 0 0 1 1 1 1 Calpain family cysteine protease Gemini_C4 PF01492.17 KFY04046.1 - 0.014 15.3 0.0 0.033 14.1 0.0 1.5 1 0 0 1 1 1 0 Geminivirus C4 protein DUF4775 PF16001.5 KFY04046.1 - 0.14 11.5 0.2 0.21 10.9 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4775) MIT PF04212.18 KFY04046.1 - 0.17 12.0 2.5 0.31 11.1 2.5 1.4 1 0 0 1 1 1 0 MIT (microtubule interacting and transport) domain SAM_2 PF07647.17 KFY04047.1 - 1e-09 38.3 0.1 2e-09 37.4 0.1 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 KFY04047.1 - 5.1e-05 23.6 0.1 0.00011 22.6 0.1 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) ALIX_LYPXL_bnd PF13949.6 KFY04047.1 - 0.0065 15.8 1.0 0.01 15.1 1.0 1.3 1 0 0 1 1 1 1 ALIX V-shaped domain binding to HIV IGR PF09597.10 KFY04047.1 - 0.063 13.4 0.1 0.18 12.0 0.1 1.7 1 0 0 1 1 1 0 IGR protein motif DUF4508 PF14969.6 KFY04047.1 - 0.14 12.4 0.1 0.4 11.0 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4508) MerR-DNA-bind PF09278.11 KFY04047.1 - 0.22 12.1 0.7 0.62 10.6 0.7 1.8 1 0 0 1 1 1 0 MerR, DNA binding TPR_19 PF14559.6 KFY04048.1 - 2.8e-13 50.2 19.6 5.8e-05 23.5 2.2 7.7 5 2 2 7 7 7 3 Tetratricopeptide repeat TPR_8 PF13181.6 KFY04048.1 - 1.1e-11 43.9 19.6 0.00013 21.9 0.1 9.2 9 0 0 9 9 8 2 Tetratricopeptide repeat TPR_14 PF13428.6 KFY04048.1 - 1.2e-09 38.2 20.8 0.039 14.8 0.0 9.8 7 2 3 10 10 9 3 Tetratricopeptide repeat TPR_17 PF13431.6 KFY04048.1 - 2.4e-08 33.8 0.3 0.046 14.1 0.1 5.5 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_11 PF13414.6 KFY04048.1 - 2.2e-07 30.4 12.1 0.00043 19.9 0.4 6.2 5 2 2 7 7 7 2 TPR repeat TPR_12 PF13424.6 KFY04048.1 - 1.4e-06 28.5 30.5 0.061 13.6 1.6 8.4 7 3 1 8 8 7 3 Tetratricopeptide repeat TPR_2 PF07719.17 KFY04048.1 - 2.8e-06 27.0 38.3 0.0016 18.4 0.1 12.3 14 0 0 14 14 14 2 Tetratricopeptide repeat TPR_1 PF00515.28 KFY04048.1 - 3.3e-06 26.7 39.1 6.2e-05 22.6 0.2 10.7 12 0 0 12 12 12 2 Tetratricopeptide repeat Alkyl_sulf_dimr PF14863.6 KFY04048.1 - 1.4e-05 25.5 0.8 0.89 10.0 0.2 3.6 3 0 0 3 3 3 2 Alkyl sulfatase dimerisation ANAPC3 PF12895.7 KFY04048.1 - 1.5e-05 25.1 15.1 0.12 12.6 3.4 5.1 4 0 0 4 4 4 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.6 KFY04048.1 - 1.5e-05 25.5 21.1 0.4 11.4 0.0 7.1 7 1 0 8 8 7 3 Tetratricopeptide repeat TPR_7 PF13176.6 KFY04048.1 - 0.00092 19.1 18.6 0.044 13.8 0.1 7.4 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_20 PF14561.6 KFY04048.1 - 0.0022 18.3 16.2 0.23 11.8 1.9 5.8 6 2 1 8 8 5 2 Tetratricopeptide repeat RPN7 PF10602.9 KFY04048.1 - 0.0087 15.8 0.3 5.9 6.6 0.1 3.3 3 1 0 3 3 3 1 26S proteasome subunit RPN7 ChAPs PF09295.10 KFY04048.1 - 0.01 14.8 4.4 0.63 9.0 0.6 3.1 3 0 0 3 3 3 0 ChAPs (Chs5p-Arf1p-binding proteins) TPR_6 PF13174.6 KFY04048.1 - 0.071 13.8 23.5 0.99 10.2 0.1 8.1 10 0 0 10 10 8 0 Tetratricopeptide repeat TPR_9 PF13371.6 KFY04048.1 - 0.091 12.9 4.1 51 4.1 0.3 4.6 4 1 0 4 4 4 0 Tetratricopeptide repeat BTAD PF03704.17 KFY04048.1 - 0.16 12.4 0.0 0.16 12.4 0.0 4.0 4 2 1 5 5 3 0 Bacterial transcriptional activator domain Sec23_trunk PF04811.15 KFY04049.1 - 1.3e-80 270.5 0.0 1.8e-80 270.0 0.0 1.2 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_BS PF08033.12 KFY04049.1 - 5.7e-31 107.1 0.3 1.4e-30 105.9 0.3 1.7 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain Sec23_helical PF04815.15 KFY04049.1 - 5.5e-25 87.2 0.1 1.6e-24 85.7 0.1 1.9 1 0 0 1 1 1 1 Sec23/Sec24 helical domain zf-Sec23_Sec24 PF04810.15 KFY04049.1 - 4e-15 55.6 5.2 7.6e-15 54.7 5.2 1.5 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.22 KFY04049.1 - 1.5e-13 50.5 0.0 4.2e-13 49.0 0.0 1.8 2 0 0 2 2 2 1 Gelsolin repeat Vps36-NZF-N PF16988.5 KFY04049.1 - 0.063 12.7 0.1 0.14 11.6 0.1 1.5 1 0 0 1 1 1 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain Ribosomal_L22 PF00237.19 KFY04050.1 - 4.6e-41 139.2 0.1 6.7e-41 138.7 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e Lipl32 PF12103.8 KFY04050.1 - 0.028 14.1 0.1 0.045 13.4 0.1 1.3 1 0 0 1 1 1 0 Surface lipoprotein of Spirochaetales order LTD PF00932.19 KFY04050.1 - 0.088 13.2 0.0 0.14 12.6 0.0 1.4 1 0 0 1 1 1 0 Lamin Tail Domain Helicase_PWI PF18149.1 KFY04062.1 - 0.0063 16.7 0.0 0.01 16.0 0.0 1.3 1 0 0 1 1 1 1 N-terminal helicase PWI domain SUB1_ProdP9 PF18213.1 KFY04062.1 - 0.059 13.2 0.1 0.49 10.3 0.0 2.2 2 1 1 3 3 3 0 SUB1 protease Prodomain ProdP9 FMN_dh PF01070.18 KFY04063.1 - 5.4e-121 403.9 0.1 7.3e-121 403.4 0.1 1.2 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.28 KFY04063.1 - 1.1e-22 79.9 0.0 2.6e-22 78.7 0.0 1.7 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Synaptobrevin PF00957.21 KFY04063.1 - 1.4e-12 47.2 0.5 1.4e-12 47.2 0.5 1.9 2 0 0 2 2 2 1 Synaptobrevin Longin PF13774.6 KFY04063.1 - 1.5e-09 37.7 0.0 3.4e-09 36.6 0.0 1.6 1 0 0 1 1 1 1 Regulated-SNARE-like domain Glu_synthase PF01645.17 KFY04063.1 - 7.7e-09 35.2 0.1 1.3e-08 34.4 0.1 1.3 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.25 KFY04063.1 - 0.0004 19.5 0.6 0.00093 18.3 0.4 1.7 1 1 1 2 2 2 1 IMP dehydrogenase / GMP reductase domain NMO PF03060.15 KFY04063.1 - 0.031 13.7 0.7 0.059 12.7 0.2 1.7 2 0 0 2 2 2 0 Nitronate monooxygenase ThiG PF05690.14 KFY04063.1 - 0.047 13.0 0.3 1.4 8.2 0.1 2.4 2 0 0 2 2 2 0 Thiazole biosynthesis protein ThiG DUF4556 PF15094.6 KFY04063.1 - 0.065 12.4 0.0 0.14 11.4 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4556) HMGL-like PF00682.19 KFY04064.1 - 8.5e-80 268.1 0.2 1.2e-79 267.6 0.2 1.2 1 0 0 1 1 1 1 HMGL-like BRX_N PF13713.6 KFY04064.1 - 0.024 14.4 0.4 0.093 12.5 0.4 2.0 1 0 0 1 1 1 0 Transcription factor BRX N-terminal domain Glyco_hydro_61 PF03443.14 KFY04065.1 - 9.1e-50 169.4 0.0 1.1e-49 169.2 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Cadherin_pro PF08758.11 KFY04065.1 - 0.00088 19.4 0.0 0.0016 18.6 0.0 1.4 1 0 0 1 1 1 1 Cadherin prodomain like WD40 PF00400.32 KFY04068.1 - 4.6e-20 71.6 1.4 3.1e-11 43.7 0.1 3.6 4 0 0 4 4 4 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFY04068.1 - 5.9e-07 29.7 0.0 0.094 13.0 0.0 3.2 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 KFY04068.1 - 0.015 14.7 0.0 3.3 7.0 0.0 2.8 2 1 1 3 3 3 0 WD40-like domain Roc PF08477.13 KFY04068.1 - 0.18 12.0 0.1 0.49 10.6 0.1 1.7 1 1 1 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Glyco_hydro_18 PF00704.28 KFY04070.1 - 1.9e-74 251.2 0.5 2.3e-74 250.9 0.5 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Imm58 PF15581.6 KFY04071.1 - 0.0096 16.0 0.1 0.016 15.3 0.1 1.3 1 0 0 1 1 1 1 Immunity protein 58 F-box PF00646.33 KFY04071.1 - 0.14 12.1 0.1 0.39 10.6 0.1 1.8 1 0 0 1 1 1 0 F-box domain Phage_holin_2_3 PF16080.5 KFY04072.1 - 0.12 12.1 1.0 2.8 7.8 0.1 2.5 2 0 0 2 2 2 0 Bacteriophage holin family HP1 DUF3723 PF12520.8 KFY04073.1 - 2.2e-118 396.1 0.0 2.9e-118 395.8 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3723) Abhydrolase_6 PF12697.7 KFY04074.1 - 1.5e-12 48.6 3.0 2.3e-12 48.0 3.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KFY04074.1 - 1.2e-08 34.5 0.0 1.7e-08 34.1 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 KFY04074.1 - 2.3e-06 27.5 1.3 2.6e-06 27.3 0.5 1.4 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_3 PF07859.13 KFY04074.1 - 0.00092 19.1 0.0 0.0016 18.4 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold AXE1 PF05448.12 KFY04074.1 - 0.065 11.9 0.1 1.1 7.9 0.0 2.2 2 0 0 2 2 2 0 Acetyl xylan esterase (AXE1) Tropomyosin_1 PF12718.7 KFY04076.1 - 0.19 11.9 13.6 0.052 13.7 5.2 2.1 1 1 1 2 2 2 0 Tropomyosin like RSN1_7TM PF02714.15 KFY04077.1 - 3.2e-77 259.5 24.1 3.2e-77 259.5 24.1 2.0 2 0 0 2 2 2 1 Calcium-dependent channel, 7TM region, putative phosphate RSN1_TM PF13967.6 KFY04077.1 - 9.7e-43 145.6 1.4 9.7e-43 145.6 1.4 3.8 3 1 0 3 3 3 1 Late exocytosis, associated with Golgi transport HlyIII PF03006.20 KFY04077.1 - 2.6e-38 132.0 11.5 2.6e-38 132.0 11.5 4.1 3 1 0 3 3 3 1 Haemolysin-III related PHM7_cyt PF14703.6 KFY04077.1 - 9.6e-29 100.8 4.0 2.6e-17 63.6 0.6 2.5 2 0 0 2 2 2 2 Cytosolic domain of 10TM putative phosphate transporter PHM7_ext PF12621.8 KFY04077.1 - 2e-11 43.9 0.0 7.2e-11 42.1 0.0 2.0 1 0 0 1 1 1 1 Extracellular tail, of 10TM putative phosphate transporter Transketolase_N PF00456.21 KFY04078.1 - 0.04 12.9 1.1 0.054 12.4 1.1 1.2 1 0 0 1 1 1 0 Transketolase, thiamine diphosphate binding domain DDHD PF02862.17 KFY04078.1 - 0.19 11.8 0.7 11 6.1 0.2 2.2 2 0 0 2 2 2 0 DDHD domain Ank_2 PF12796.7 KFY04079.1 - 3e-62 207.2 15.0 8.3e-14 51.9 0.2 5.4 2 1 5 7 7 7 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KFY04079.1 - 1.3e-40 137.3 7.5 6.4e-08 33.0 0.1 6.6 3 2 4 7 7 7 7 Ankyrin repeats (many copies) Ank PF00023.30 KFY04079.1 - 1.5e-37 126.4 10.4 1.7e-06 28.2 0.0 8.1 8 0 0 8 8 8 7 Ankyrin repeat Ank_3 PF13606.6 KFY04079.1 - 2.3e-33 110.4 8.5 4.3e-06 26.7 0.0 8.9 9 0 0 9 9 9 7 Ankyrin repeat Ank_5 PF13857.6 KFY04079.1 - 1.1e-26 92.6 10.4 6.5e-07 29.5 0.2 7.2 4 2 4 8 8 8 6 Ankyrin repeats (many copies) Mic1 PF07035.12 KFY04079.1 - 0.14 11.8 0.0 9.6 5.9 0.0 2.9 3 0 0 3 3 3 0 Colon cancer-associated protein Mic1-like WD40 PF00400.32 KFY04080.1 - 4.9e-98 318.3 52.6 1e-09 38.8 0.1 11.8 11 0 0 11 11 11 11 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFY04080.1 - 1.4e-30 105.4 33.1 0.0012 19.1 0.2 11.6 3 1 9 12 12 10 10 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KFY04080.1 - 2.7e-15 56.0 37.6 0.079 11.6 0.1 11.0 1 1 10 11 11 11 8 Nucleoporin Nup120/160 Nbas_N PF15492.6 KFY04080.1 - 2.2e-10 40.4 22.4 0.091 12.1 0.1 9.1 1 1 10 11 11 11 4 Neuroblastoma-amplified sequence, N terminal Nucleoporin_N PF08801.11 KFY04080.1 - 6.6e-10 38.3 36.3 0.00018 20.4 6.2 6.1 1 1 5 6 6 6 6 Nup133 N terminal like NACHT PF05729.12 KFY04080.1 - 3.2e-08 33.7 0.0 1e-07 32.1 0.0 1.9 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 KFY04080.1 - 8.6e-08 32.7 0.1 3.9e-07 30.6 0.1 2.1 1 0 0 1 1 1 1 AAA ATPase domain Helo_like_N PF17111.5 KFY04080.1 - 0.00029 20.3 0.6 0.00078 18.9 0.6 1.8 1 0 0 1 1 1 1 Fungal N-terminal domain of STAND proteins NYD-SP28_assoc PF14775.6 KFY04080.1 - 0.00088 19.3 9.6 48 4.2 0.0 7.8 9 0 0 9 9 8 0 Sperm tail C-terminal domain WD40_like PF17005.5 KFY04080.1 - 0.00089 18.7 11.6 1.2 8.4 0.2 4.9 1 1 1 4 4 4 2 WD40-like domain ATPase_2 PF01637.18 KFY04080.1 - 0.0046 16.9 0.0 0.01 15.8 0.0 1.5 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea AAA_22 PF13401.6 KFY04080.1 - 0.0057 16.9 0.3 0.19 12.0 0.0 2.9 3 0 0 3 3 3 1 AAA domain AAA_18 PF13238.6 KFY04080.1 - 0.0076 16.8 0.8 0.38 11.3 0.0 3.8 4 1 0 4 4 2 1 AAA domain AAA_30 PF13604.6 KFY04080.1 - 0.045 13.5 0.2 0.14 11.9 0.0 1.9 2 0 0 2 2 2 0 AAA domain WXG100 PF06013.12 KFY04080.1 - 0.048 13.9 6.4 12 6.2 0.0 5.5 6 0 0 6 6 5 0 Proteins of 100 residues with WXG AAA PF00004.29 KFY04080.1 - 0.096 13.1 0.4 0.92 9.9 0.0 2.8 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) FlxA PF14282.6 KFY04080.1 - 0.1 12.6 0.1 0.25 11.4 0.1 1.6 1 0 0 1 1 1 0 FlxA-like protein APS_kinase PF01583.20 KFY04080.1 - 0.13 12.2 0.0 0.31 10.9 0.0 1.6 1 0 0 1 1 1 0 Adenylylsulphate kinase DUF2777 PF10949.8 KFY04080.1 - 0.18 11.5 6.1 17 5.0 0.1 5.0 4 1 1 5 5 5 0 Protein of unknown function (DUF2777) FAS_meander PF17951.1 KFY04080.1 - 0.77 9.6 3.9 0.64 9.8 0.1 2.9 4 0 0 4 4 4 0 Fatty acid synthase meander beta sheet domain AHJR-like PF18743.1 KFY04080.1 - 2 8.0 7.4 13 5.4 0.1 4.4 4 1 1 5 5 5 0 REase_AHJR-like bZIP_1 PF00170.21 KFY04086.1 - 2.5e-08 33.9 11.5 2.5e-08 33.9 11.5 1.8 2 0 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.15 KFY04086.1 - 0.00046 20.2 10.6 0.00046 20.2 10.6 2.2 2 0 0 2 2 2 1 Basic region leucine zipper DivIC PF04977.15 KFY04086.1 - 0.21 11.4 9.2 1.9 8.3 0.9 2.6 2 0 0 2 2 2 0 Septum formation initiator adh_short PF00106.25 KFY04087.1 - 2.8e-20 72.6 0.4 1.4e-18 67.1 0.2 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KFY04087.1 - 1.9e-13 50.5 0.5 8.6e-13 48.4 0.2 1.9 1 1 1 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KFY04087.1 - 2.5e-06 27.5 0.5 4.3e-06 26.8 0.5 1.3 1 0 0 1 1 1 1 KR domain Sensor PF13796.6 KFY04087.1 - 0.097 12.7 1.3 0.27 11.3 0.9 2.0 2 1 0 2 2 2 0 Putative sensor Fungal_trans PF04082.18 KFY04088.1 - 0.076 12.0 0.0 0.12 11.4 0.0 1.3 1 0 0 1 1 1 0 Fungal specific transcription factor domain cobW PF02492.19 KFY04089.1 - 2.1e-46 157.7 0.3 3.4e-46 157.0 0.3 1.3 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain NOT2_3_5 PF04153.18 KFY04089.1 - 3.8e-31 107.9 1.4 7.6e-31 106.9 1.4 1.5 1 0 0 1 1 1 1 NOT2 / NOT3 / NOT5 family RsgA_GTPase PF03193.16 KFY04089.1 - 5.6e-06 26.4 0.1 0.037 13.9 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase CobW_C PF07683.14 KFY04089.1 - 0.0038 17.1 0.0 0.0096 15.8 0.0 1.6 1 0 0 1 1 1 1 Cobalamin synthesis protein cobW C-terminal domain AAA_22 PF13401.6 KFY04089.1 - 0.019 15.3 0.3 1.3 9.3 0.0 2.5 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.23 KFY04089.1 - 0.034 14.2 0.0 0.084 13.0 0.0 1.6 1 1 0 1 1 1 0 50S ribosome-binding GTPase ATP_bind_1 PF03029.17 KFY04089.1 - 0.045 13.5 0.4 0.18 11.6 0.4 1.9 1 1 0 1 1 1 0 Conserved hypothetical ATP binding protein TsaE PF02367.17 KFY04089.1 - 0.052 13.5 0.2 0.17 11.9 0.1 1.8 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE GTP_EFTU PF00009.27 KFY04089.1 - 0.061 12.9 1.6 1.2 8.6 1.6 2.2 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain Septin PF00735.18 KFY04089.1 - 0.069 12.4 0.1 11 5.2 0.0 2.2 2 0 0 2 2 2 0 Septin AAA_16 PF13191.6 KFY04089.1 - 0.081 13.3 0.4 0.25 11.7 0.0 2.0 2 0 0 2 2 2 0 AAA ATPase domain AAA_23 PF13476.6 KFY04089.1 - 0.097 13.2 0.1 0.24 11.9 0.1 1.6 1 0 0 1 1 1 0 AAA domain MeaB PF03308.16 KFY04089.1 - 0.11 11.4 0.5 6.5 5.7 0.0 2.6 3 0 0 3 3 3 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Mob1_phocein PF03637.17 KFY04090.1 - 3.4e-22 79.3 0.0 5.4e-22 78.6 0.0 1.2 1 0 0 1 1 1 1 Mob1/phocein family CxC6 PF18721.1 KFY04090.1 - 0.039 14.2 3.9 0.094 13.0 3.9 1.6 1 0 0 1 1 1 0 CxC6 like cysteine cluster associated with KDZ transposases Na_Ca_ex PF01699.24 KFY04091.1 - 3.8e-28 98.3 28.4 4.2e-15 56.0 10.0 2.1 2 0 0 2 2 2 2 Sodium/calcium exchanger protein RDD PF06271.12 KFY04091.1 - 0.085 13.1 12.4 4.8 7.4 0.2 3.8 3 1 0 3 3 3 0 RDD family DEAD PF00270.29 KFY04093.1 - 3.6e-28 98.5 0.0 5.8e-28 97.8 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF1998 PF09369.10 KFY04093.1 - 2.1e-22 79.6 0.2 7.1e-22 78.0 0.2 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1998) Yip1 PF04893.17 KFY04093.1 - 1.1e-13 51.3 8.8 2.3e-13 50.2 8.8 1.5 1 0 0 1 1 1 1 Yip1 domain Ran_BP1 PF00638.18 KFY04093.1 - 1.8e-12 47.5 0.1 2.3e-07 31.1 0.0 2.5 2 0 0 2 2 2 2 RanBP1 domain Helicase_C PF00271.31 KFY04093.1 - 7.6e-12 45.6 0.0 2.7e-11 43.8 0.0 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KFY04093.1 - 8.8e-07 29.1 0.1 1.7e-06 28.1 0.1 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit CDT1 PF08839.11 KFY04093.1 - 1.5e-06 28.6 0.1 2.9e-06 27.7 0.1 1.4 1 0 0 1 1 1 1 DNA replication factor CDT1 like DUF1282 PF06930.12 KFY04093.1 - 0.34 10.7 2.8 0.59 9.9 2.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1282) WD40 PF00400.32 KFY04094.1 - 1.9e-15 57.0 8.1 2.4e-05 25.0 0.1 4.9 4 0 0 4 4 4 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFY04094.1 - 2.8e-05 24.3 0.7 2 8.7 0.0 4.1 2 1 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain RNA_pol_I_TF PF04090.12 KFY04095.1 - 7e-07 28.9 0.0 6e-05 22.6 0.0 2.3 2 0 0 2 2 2 2 RNA polymerase I specific initiation factor SNF2_N PF00176.23 KFY04096.1 - 2.9e-71 240.0 0.2 6.4e-71 238.9 0.0 1.6 2 0 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KFY04096.1 - 4.7e-13 49.5 0.0 1.6e-12 47.7 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 KFY04096.1 - 4.9e-06 26.4 0.0 9.9e-06 25.4 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase zf-RING_5 PF14634.6 KFY04096.1 - 3.1e-05 23.8 5.7 6.6e-05 22.8 5.7 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 KFY04096.1 - 0.0017 18.2 7.0 0.0028 17.5 3.9 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KFY04096.1 - 0.0058 16.5 5.8 0.017 15.0 5.8 1.8 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) ResIII PF04851.15 KFY04096.1 - 0.042 13.8 0.0 0.11 12.5 0.0 1.8 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit Prok-RING_4 PF14447.6 KFY04096.1 - 0.23 11.4 7.6 2.1 8.3 7.9 2.5 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 KFY04096.1 - 0.35 10.9 2.1 1.1 9.3 2.1 1.8 1 1 0 1 1 1 0 RING-type zinc-finger zf-RING_2 PF13639.6 KFY04096.1 - 0.69 10.3 3.8 1.6 9.1 3.8 1.7 1 0 0 1 1 1 0 Ring finger domain PI3_PI4_kinase PF00454.27 KFY04097.1 - 4.6e-41 141.3 0.0 6.5e-41 140.8 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase GATA PF00320.27 KFY04098.1 - 3.4e-14 52.1 2.4 6.7e-14 51.2 2.4 1.5 1 0 0 1 1 1 1 GATA zinc finger Atg14 PF10186.9 KFY04098.1 - 0.11 11.6 8.3 0.22 10.6 8.3 1.4 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 CENP-F_leu_zip PF10473.9 KFY04098.1 - 0.3 11.1 11.5 4.9 7.2 6.3 2.1 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DivIVA PF05103.13 KFY04098.1 - 0.48 10.5 6.7 0.85 9.7 6.7 1.3 1 0 0 1 1 1 0 DivIVA protein UPF0242 PF06785.11 KFY04098.1 - 0.76 9.9 5.4 1.1 9.3 5.4 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Phlebovirus_NSM PF07246.11 KFY04098.1 - 1.2 8.5 4.3 1.8 7.9 4.3 1.2 1 0 0 1 1 1 0 Phlebovirus nonstructural protein NS-M FAM76 PF16046.5 KFY04098.1 - 1.5 8.1 5.8 19 4.5 5.8 2.0 1 1 0 1 1 1 0 FAM76 protein DivIC PF04977.15 KFY04098.1 - 3.8 7.3 9.5 2.2 8.1 3.9 2.2 2 0 0 2 2 2 0 Septum formation initiator Spermine_synth PF01564.17 KFY04099.1 - 2.1e-09 37.0 0.0 3.6e-09 36.3 0.0 1.3 1 0 0 1 1 1 1 Spermine/spermidine synthase domain Methyltransf_25 PF13649.6 KFY04099.1 - 0.003 18.2 0.0 0.0074 17.0 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KFY04099.1 - 0.0064 17.2 0.0 0.018 15.8 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KFY04099.1 - 0.0081 16.8 0.0 0.033 14.8 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KFY04099.1 - 0.016 15.0 0.0 0.034 14.0 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_30 PF05430.11 KFY04099.1 - 0.058 13.3 0.1 0.13 12.1 0.0 1.6 2 0 0 2 2 2 0 S-adenosyl-L-methionine-dependent methyltransferase AlaDh_PNT_C PF01262.21 KFY04099.1 - 0.061 12.6 0.1 0.12 11.7 0.1 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Methyltransf_31 PF13847.6 KFY04099.1 - 0.08 12.7 0.0 0.15 11.8 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain CorA PF01544.18 KFY04101.1 - 3e-08 33.3 0.5 5.2e-08 32.6 0.5 1.3 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein Seipin PF06775.14 KFY04102.1 - 3.8e-35 121.8 0.1 4.9e-35 121.4 0.1 1.1 1 0 0 1 1 1 1 Putative adipose-regulatory protein (Seipin) QCR10 PF09796.9 KFY04102.1 - 0.037 14.1 0.3 0.037 14.1 0.3 1.9 2 0 0 2 2 2 0 Ubiquinol-cytochrome-c reductase complex subunit (QCR10) Nic96 PF04097.14 KFY04103.1 - 4.2e-201 669.6 0.0 5.8e-201 669.2 0.0 1.1 1 0 0 1 1 1 1 Nup93/Nic96 UPF0029 PF01205.19 KFY04103.1 - 4.3e-29 100.9 0.0 1.2e-28 99.5 0.0 1.8 1 0 0 1 1 1 1 Uncharacterized protein family UPF0029 Nucleoporin_FG PF13634.6 KFY04103.1 - 6.1 7.8 45.8 1.7 9.6 34.7 3.2 2 1 0 2 2 2 0 Nucleoporin FG repeat region VTC PF09359.10 KFY04105.1 - 5.9e-95 317.8 0.7 1e-94 317.0 0.7 1.4 1 0 0 1 1 1 1 VTC domain DUF202 PF02656.15 KFY04105.1 - 1.1e-13 51.4 3.3 2.5e-13 50.2 3.3 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF202) SPX PF03105.19 KFY04105.1 - 4.2e-09 36.8 10.4 0.00053 20.0 1.3 3.5 1 1 2 3 3 3 3 SPX domain Seryl_tRNA_N PF02403.22 KFY04105.1 - 0.35 11.1 4.7 0.36 11.1 1.4 2.3 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Inhibitor_I34 PF10466.9 KFY04105.1 - 4.6 7.9 5.7 1 10.0 0.9 2.3 2 0 0 2 2 2 0 Saccharopepsin inhibitor I34 GATase_2 PF00310.21 KFY04106.1 - 3.2e-181 602.6 0.0 4.9e-181 602.0 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferases class-II Glu_synthase PF01645.17 KFY04106.1 - 1e-156 521.8 0.0 1.8e-156 520.9 0.0 1.4 2 0 0 2 2 2 1 Conserved region in glutamate synthase Glu_syn_central PF04898.14 KFY04106.1 - 2.9e-111 371.5 0.0 1.4e-109 366.0 0.0 2.3 2 0 0 2 2 2 1 Glutamate synthase central domain GXGXG PF01493.19 KFY04106.1 - 1.2e-85 285.9 5.1 2e-85 285.2 5.1 1.4 1 0 0 1 1 1 1 GXGXG motif Fer4_20 PF14691.6 KFY04106.1 - 1.1e-21 76.7 0.1 2.4e-21 75.6 0.1 1.6 1 0 0 1 1 1 1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster Pyr_redox_2 PF07992.14 KFY04106.1 - 1.4e-21 77.0 0.0 5.8e-21 75.0 0.0 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KFY04106.1 - 3.2e-08 33.7 0.0 1.1e-07 32.0 0.0 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KFY04106.1 - 5.6e-08 32.7 0.2 0.00044 19.9 0.1 2.4 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox PF00070.27 KFY04106.1 - 4.9e-07 30.2 0.0 0.0013 19.2 0.0 2.8 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KFY04106.1 - 1.9e-05 23.6 0.0 5.9e-05 21.9 0.1 1.8 2 0 0 2 2 2 1 HI0933-like protein Amino_oxidase PF01593.24 KFY04106.1 - 3.7e-05 23.2 0.0 7.7e-05 22.2 0.0 1.5 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase Pyr_redox_3 PF13738.6 KFY04106.1 - 0.00019 20.8 0.5 0.033 13.5 0.1 3.0 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KFY04106.1 - 0.0013 17.9 0.1 0.0047 16.1 0.0 2.0 2 0 0 2 2 2 1 FAD binding domain Thi4 PF01946.17 KFY04106.1 - 0.0025 17.1 0.1 0.012 14.9 0.1 2.1 2 0 0 2 2 2 1 Thi4 family NAD_binding_7 PF13241.6 KFY04106.1 - 0.0048 17.3 1.7 3.6 8.1 0.1 3.0 3 0 0 3 3 2 2 Putative NAD(P)-binding AdoHcyase_NAD PF00670.21 KFY04106.1 - 0.0074 16.4 0.3 5.8 7.0 0.0 2.7 2 0 0 2 2 2 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain FAD_binding_3 PF01494.19 KFY04106.1 - 0.0078 15.5 0.0 0.015 14.5 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.7 KFY04106.1 - 0.017 14.5 0.0 0.033 13.5 0.0 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase FMO-like PF00743.19 KFY04106.1 - 0.019 13.4 0.1 5.8 5.2 0.0 2.7 2 1 1 3 3 3 0 Flavin-binding monooxygenase-like FMN_dh PF01070.18 KFY04106.1 - 0.03 13.4 0.6 0.12 11.4 0.6 2.0 3 0 0 3 3 3 0 FMN-dependent dehydrogenase NAD_Gly3P_dh_N PF01210.23 KFY04106.1 - 0.05 13.6 0.0 0.11 12.4 0.0 1.6 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus AlaDh_PNT_C PF01262.21 KFY04106.1 - 0.07 12.4 0.1 7.9 5.7 0.0 2.3 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain Lycopene_cycl PF05834.12 KFY04106.1 - 0.076 12.0 0.1 0.74 8.8 0.1 2.3 2 0 0 2 2 2 0 Lycopene cyclase protein Apc15p PF05841.11 KFY04107.1 - 1.1e-17 65.0 0.8 4.7e-17 62.9 0.8 2.0 1 1 0 1 1 1 1 Apc15p protein Use1 PF09753.9 KFY04108.1 - 0.00042 20.1 0.0 0.00042 20.1 0.0 1.1 1 0 0 1 1 1 1 Membrane fusion protein Use1 Sipho_Gp157 PF05565.11 KFY04108.1 - 0.033 14.2 0.1 0.039 13.9 0.1 1.1 1 0 0 1 1 1 0 Siphovirus Gp157 CHZ PF09649.10 KFY04109.1 - 1.9e-19 68.8 2.9 1.9e-19 68.8 2.9 2.6 3 1 0 3 3 3 1 Histone chaperone domain CHZ PPP4R2 PF09184.11 KFY04109.1 - 5.5 6.5 14.1 6.4 6.3 14.1 1.1 1 0 0 1 1 1 0 PPP4R2 6PF2K PF01591.18 KFY04110.1 - 9.2e-63 211.5 0.0 1.1e-43 149.1 0.0 2.3 2 0 0 2 2 2 2 6-phosphofructo-2-kinase His_Phos_1 PF00300.22 KFY04110.1 - 1.7e-26 93.1 0.0 7e-22 78.1 0.0 2.4 2 0 0 2 2 2 2 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.6 KFY04110.1 - 0.0035 17.5 0.3 0.12 12.6 0.1 2.7 2 1 0 2 2 2 1 AAA domain KTI12 PF08433.10 KFY04110.1 - 0.02 14.3 0.0 0.056 12.9 0.0 1.7 2 0 0 2 2 2 0 Chromatin associated protein KTI12 CARD PF00619.21 KFY04110.1 - 0.15 12.2 0.2 0.48 10.5 0.2 1.8 1 1 0 1 1 1 0 Caspase recruitment domain Zeta_toxin PF06414.12 KFY04110.1 - 0.15 11.4 0.0 0.28 10.4 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin Arm PF00514.23 KFY04111.1 - 2.1e-13 49.8 14.6 3.2e-05 23.8 0.1 9.1 10 0 0 10 10 10 2 Armadillo/beta-catenin-like repeat HEAT PF02985.22 KFY04111.1 - 3.9e-07 29.8 10.0 3.2 8.2 0.1 7.7 7 0 0 7 7 7 3 HEAT repeat HEAT_EZ PF13513.6 KFY04111.1 - 8.2e-07 29.4 5.2 0.11 13.0 0.1 6.1 6 0 0 6 6 6 2 HEAT-like repeat V-ATPase_H_C PF11698.8 KFY04111.1 - 0.035 14.2 0.5 4.3 7.5 0.0 3.2 2 1 1 3 3 3 0 V-ATPase subunit H DUF4148 PF13663.6 KFY04111.1 - 0.059 13.6 1.7 5.4 7.3 0.1 3.3 2 1 0 2 2 2 0 Domain of unknown function (DUF4148) DUF3361 PF11841.8 KFY04111.1 - 0.078 12.9 0.2 0.42 10.6 0.2 2.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3361) dCMP_cyt_deam_1 PF00383.23 KFY04112.1 - 6.1e-08 32.5 0.1 2e-07 30.8 0.1 1.8 1 1 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 KFY04112.1 - 0.0023 17.7 0.0 0.0045 16.7 0.0 1.4 1 0 0 1 1 1 1 MafB19-like deaminase APOBEC3 PF18771.1 KFY04112.1 - 0.16 12.1 0.0 0.57 10.3 0.0 1.8 2 0 0 2 2 2 0 APOBEC3 Cauli_VI PF01693.16 KFY04113.1 - 5.2e-38 129.1 6.3 3.2e-20 72.2 0.6 2.5 2 0 0 2 2 2 2 Caulimovirus viroplasmin RNase_H PF00075.24 KFY04113.1 - 5.2e-36 124.0 0.0 8.9e-36 123.2 0.0 1.4 1 0 0 1 1 1 1 RNase H RVT_3 PF13456.6 KFY04113.1 - 0.015 15.1 0.0 0.033 14.0 0.0 1.6 1 0 0 1 1 1 0 Reverse transcriptase-like Ank PF00023.30 KFY04114.1 - 2.7e-11 43.4 0.0 7.5e-05 23.0 0.0 3.1 3 0 0 3 3 3 2 Ankyrin repeat TIG PF01833.24 KFY04114.1 - 1.8e-09 37.5 0.4 5.9e-09 35.9 0.4 1.9 1 0 0 1 1 1 1 IPT/TIG domain Ank_2 PF12796.7 KFY04114.1 - 4.9e-09 36.7 0.0 1e-08 35.7 0.0 1.4 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KFY04114.1 - 2.4e-08 34.4 0.0 6.8e-07 29.7 0.0 2.4 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFY04114.1 - 4.6e-08 32.7 0.1 0.0006 20.1 0.0 2.8 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.6 KFY04114.1 - 7.4e-08 32.5 0.1 0.00041 20.6 0.0 2.7 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Herpes_LMP1 PF05297.11 KFY04115.1 - 0.84 8.8 3.4 1.6 7.8 3.4 1.4 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) Glyoxalase PF00903.25 KFY04116.1 - 1.3e-05 25.4 0.0 1.8e-05 24.9 0.0 1.5 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily adh_short PF00106.25 KFY04117.1 - 1.1e-26 93.5 1.3 2e-26 92.7 1.3 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KFY04117.1 - 2.1e-16 60.2 0.9 3e-16 59.7 0.9 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Acetyltransf_10 PF13673.7 KFY04117.1 - 6.5e-10 39.0 0.0 1.3e-09 38.0 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KFY04117.1 - 1.6e-09 38.0 0.1 4.9e-09 36.5 0.1 1.9 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KFY04117.1 - 1.4e-08 35.0 0.1 2.8e-08 34.0 0.1 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family KR PF08659.10 KFY04117.1 - 1.4e-07 31.6 0.1 7.3e-07 29.3 0.0 2.2 3 0 0 3 3 3 1 KR domain FR47 PF08445.10 KFY04117.1 - 7.9e-06 25.7 0.0 3.8e-05 23.6 0.0 2.1 2 0 0 2 2 2 1 FR47-like protein Acetyltransf_9 PF13527.7 KFY04117.1 - 0.0018 18.4 0.1 0.04 14.0 0.0 2.6 2 1 0 2 2 2 1 Acetyltransferase (GNAT) domain NAD_binding_10 PF13460.6 KFY04117.1 - 0.0022 17.9 0.2 0.0054 16.6 0.2 1.8 1 0 0 1 1 1 1 NAD(P)H-binding Acetyltransf_CG PF14542.6 KFY04117.1 - 0.028 14.5 0.0 0.067 13.3 0.0 1.6 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Methyltransf_25 PF13649.6 KFY04118.1 - 4.2e-11 43.4 0.0 6e-11 42.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KFY04118.1 - 2.5e-10 40.9 0.0 3.4e-10 40.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KFY04118.1 - 0.006 16.4 0.0 0.0071 16.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KFY04118.1 - 0.007 17.1 0.0 0.012 16.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KFY04118.1 - 0.04 13.8 0.0 0.13 12.0 0.0 1.8 1 1 1 2 2 2 0 Methyltransferase domain AATase PF07247.12 KFY04120.1 - 4.5e-11 42.0 0.0 1.3e-09 37.2 0.0 2.8 1 1 0 1 1 1 1 Alcohol acetyltransferase Glyco_hydro_61 PF03443.14 KFY04121.1 - 6.4e-67 225.5 0.0 7.5e-67 225.2 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 NPCBM_assoc PF10633.9 KFY04121.1 - 0.015 15.5 0.1 0.072 13.4 0.0 2.0 2 0 0 2 2 2 0 NPCBM-associated, NEW3 domain of alpha-galactosidase CFEM PF05730.11 KFY04122.1 - 8.4e-11 41.8 10.6 1.6e-10 40.9 10.6 1.5 1 0 0 1 1 1 1 CFEM domain HlyIII PF03006.20 KFY04131.1 - 5.9e-28 98.1 14.8 7.7e-28 97.7 14.8 1.1 1 0 0 1 1 1 1 Haemolysin-III related DUF2457 PF10446.9 KFY04132.1 - 0.53 9.4 20.7 0.63 9.1 20.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) TFIIF_alpha PF05793.12 KFY04132.1 - 0.85 8.1 21.8 0.96 8.0 21.8 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Nop14 PF04147.12 KFY04132.1 - 1.7 6.8 20.1 1.8 6.6 20.1 1.0 1 0 0 1 1 1 0 Nop14-like family TRAP_alpha PF03896.16 KFY04132.1 - 1.8 7.7 11.2 2.2 7.4 11.2 1.1 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit CDC45 PF02724.14 KFY04132.1 - 9.6 4.4 13.5 10 4.3 13.5 1.1 1 0 0 1 1 1 0 CDC45-like protein p450 PF00067.22 KFY04133.1 - 2.1e-49 168.6 0.0 3.2e-49 167.9 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 zf-MYND PF01753.18 KFY04134.1 - 4.6e-10 39.4 8.6 5e-10 39.3 6.1 2.1 2 0 0 2 2 2 1 MYND finger zf-C6H2 PF15801.5 KFY04134.1 - 3.9 7.9 12.1 1.3 9.4 7.8 2.3 2 1 0 2 2 2 0 zf-MYND-like zinc finger, mRNA-binding SH3_1 PF00018.28 KFY04142.1 - 3.3e-09 36.2 0.0 5.7e-09 35.4 0.0 1.4 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 KFY04142.1 - 3.5e-07 30.0 0.1 7.4e-07 28.9 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 KFY04142.1 - 2.2e-05 24.1 0.0 4.8e-05 22.9 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain NMU PF02070.15 KFY04142.1 - 0.099 12.5 0.1 0.43 10.5 0.1 2.2 1 0 0 1 1 1 0 Neuromedin U Ssu72 PF04722.13 KFY04144.1 - 8e-84 280.0 0.0 9.2e-84 279.8 0.0 1.0 1 0 0 1 1 1 1 Ssu72-like protein GIT_SHD PF08518.11 KFY04145.1 - 1e-25 89.0 3.8 6.3e-13 48.1 0.9 2.8 2 0 0 2 2 2 2 Spa2 homology domain (SHD) of GIT Nup188_C PF18378.1 KFY04145.1 - 0.047 12.5 0.1 0.092 11.6 0.1 1.4 1 0 0 1 1 1 0 Nuclear pore protein NUP188 C-terminal domain HCMV_UL139 PF12507.8 KFY04145.1 - 0.069 13.5 2.9 1.2 9.6 1.2 2.9 2 0 0 2 2 2 0 Human Cytomegalovirus UL139 protein DUF883 PF05957.13 KFY04145.1 - 0.092 13.4 0.3 0.092 13.4 0.3 5.3 3 1 3 6 6 6 0 Bacterial protein of unknown function (DUF883) GIT1_C PF12205.8 KFY04145.1 - 0.22 11.7 0.1 0.22 11.7 0.1 3.3 4 0 0 4 4 4 0 G protein-coupled receptor kinase-interacting protein 1 C term THP2 PF09432.10 KFY04145.1 - 0.25 11.4 6.2 0.13 12.3 0.9 2.7 2 0 0 2 2 2 0 Tho complex subunit THP2 Syntaxin_2 PF14523.6 KFY04145.1 - 0.55 10.6 17.8 0.03 14.7 1.7 4.4 3 1 1 4 4 4 0 Syntaxin-like protein CLZ PF16526.5 KFY04145.1 - 1.1 9.7 21.6 1.6 9.1 0.3 4.9 5 0 0 5 5 5 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels NPV_P10 PF05531.12 KFY04145.1 - 1.9 9.0 11.5 0.58 10.7 0.3 4.6 2 2 1 4 4 4 0 Nucleopolyhedrovirus P10 protein Collagen_mid PF15984.5 KFY04145.1 - 2.3 7.9 4.3 0.98 9.1 1.5 1.7 2 0 0 2 2 2 0 Bacterial collagen, middle region DUF4407 PF14362.6 KFY04145.1 - 2.4 7.4 31.7 0.12 11.7 18.1 3.4 2 1 1 3 3 3 0 Domain of unknown function (DUF4407) DUF948 PF06103.11 KFY04145.1 - 3.2 8.1 12.0 3.3 8.0 0.1 4.5 4 1 0 4 4 4 0 Bacterial protein of unknown function (DUF948) ERM PF00769.19 KFY04145.1 - 4.4 7.1 33.9 0.034 13.9 3.9 3.2 3 0 0 3 3 3 0 Ezrin/radixin/moesin family BLOC1_2 PF10046.9 KFY04145.1 - 7.3 7.0 16.0 2 8.8 0.4 4.6 4 1 0 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Glyco_hydro_79C PF16862.5 KFY04146.1 - 3.3e-17 63.3 1.8 4.3e-17 62.9 0.5 1.9 2 0 0 2 2 2 1 Glycosyl hydrolase family 79 C-terminal beta domain Sugar_tr PF00083.24 KFY04147.1 - 1.7e-127 426.0 26.0 2e-127 425.8 26.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KFY04147.1 - 7.6e-25 87.6 37.8 1.3e-20 73.7 12.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily TPR_19 PF14559.6 KFY04147.1 - 0.022 15.2 0.1 0.036 14.6 0.1 1.3 1 0 0 1 1 1 0 Tetratricopeptide repeat DUF4131 PF13567.6 KFY04147.1 - 2 8.0 8.9 9.8 5.8 0.4 3.7 4 0 0 4 4 4 0 Domain of unknown function (DUF4131) MINDY_DUB PF04424.13 KFY04154.1 - 2.8e-21 75.7 0.0 4.7e-21 75.0 0.0 1.4 1 0 0 1 1 1 1 MINDY deubiquitinase CN_hydrolase PF00795.22 KFY04155.1 - 6.5e-42 143.7 0.0 1.1e-41 143.0 0.0 1.3 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase NAD_synthase PF02540.17 KFY04155.1 - 3.7e-22 78.6 0.0 1.4e-21 76.8 0.0 1.9 1 1 0 1 1 1 1 NAD synthase HET PF06985.11 KFY04166.1 - 6.3e-11 42.8 4.0 2.7e-08 34.3 0.7 2.5 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) ZZ PF00569.17 KFY04166.1 - 3.2e-06 26.9 10.3 5.4e-06 26.1 10.3 1.4 1 0 0 1 1 1 1 Zinc finger, ZZ type FB_lectin PF07367.11 KFY04166.1 - 0.052 13.5 0.0 0.14 12.1 0.0 1.6 1 0 0 1 1 1 0 Fungal fruit body lectin HA2 PF04408.23 KFY04166.1 - 0.097 13.0 0.0 0.18 12.1 0.0 1.4 1 0 0 1 1 1 0 Helicase associated domain (HA2) C1_2 PF03107.16 KFY04166.1 - 0.18 12.2 7.5 0.39 11.1 7.5 1.6 1 0 0 1 1 1 0 C1 domain gag-asp_proteas PF13975.6 KFY04167.1 - 0.066 13.8 0.0 5.6 7.6 0.0 2.5 2 0 0 2 2 2 0 gag-polyprotein putative aspartyl protease zf-C2H2_jaz PF12171.8 KFY04168.1 - 7.1e-08 32.5 0.2 1.2e-07 31.8 0.2 1.4 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 KFY04168.1 - 1.6e-05 25.1 0.4 2.9e-05 24.3 0.4 1.4 1 0 0 1 1 1 1 Zinc-finger of C2H2 type SNRNP27 PF08648.12 KFY04168.1 - 0.00058 19.9 0.7 0.0018 18.3 0.7 1.9 1 0 0 1 1 1 1 U4/U6.U5 small nuclear ribonucleoproteins zf-DBF PF07535.12 KFY04168.1 - 0.028 14.5 0.1 0.057 13.5 0.1 1.4 1 0 0 1 1 1 0 DBF zinc finger Atg14 PF10186.9 KFY04168.1 - 1.4 7.9 8.0 2.3 7.2 8.0 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Presenilin PF01080.17 KFY04168.1 - 6.2 5.5 6.7 9.4 4.9 6.7 1.2 1 0 0 1 1 1 0 Presenilin TP_methylase PF00590.20 KFY04169.1 - 1.6e-21 77.3 0.1 2.5e-21 76.6 0.1 1.3 1 1 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases Acyltransferase PF01553.21 KFY04175.1 - 4.4e-25 87.9 0.0 6.4e-25 87.3 0.0 1.2 1 0 0 1 1 1 1 Acyltransferase Acyltransf_C PF16076.5 KFY04175.1 - 2.5e-13 49.9 0.0 4.7e-13 49.0 0.0 1.4 1 0 0 1 1 1 1 Acyltransferase C-terminus NAD_kinase PF01513.21 KFY04176.1 - 1.5e-46 158.9 0.0 2.4e-46 158.3 0.0 1.3 1 1 0 1 1 1 1 ATP-NAD kinase Acetyltransf_7 PF13508.7 KFY04177.1 - 2.4e-05 24.7 0.1 9.5e-05 22.7 0.0 1.9 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KFY04177.1 - 0.00011 22.4 0.0 0.00024 21.3 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KFY04177.1 - 0.00033 20.6 0.0 0.00064 19.7 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KFY04177.1 - 0.0028 17.6 0.0 0.0064 16.4 0.0 1.5 1 0 0 1 1 1 1 FR47-like protein Cellulase PF00150.18 KFY04178.1 - 1.2e-51 175.9 1.7 1.4e-51 175.6 1.7 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) CBM_1 PF00734.18 KFY04178.1 - 2.2e-11 43.5 15.1 2.2e-11 43.5 15.1 2.7 3 0 0 3 3 3 1 Fungal cellulose binding domain Methyltransf_25 PF13649.6 KFY04179.1 - 6.9e-16 58.7 0.0 1.3e-15 57.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KFY04179.1 - 4.8e-13 49.6 0.0 9.2e-13 48.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KFY04179.1 - 7.2e-11 42.1 0.0 9.4e-11 41.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KFY04179.1 - 6.6e-09 35.8 0.0 9.1e-09 35.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KFY04179.1 - 6.3e-08 33.3 0.0 1.3e-07 32.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KFY04179.1 - 2.8e-05 23.6 0.0 4.2e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.14 KFY04179.1 - 5e-05 22.9 0.0 8e-05 22.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain TehB PF03848.14 KFY04179.1 - 0.00023 20.7 0.0 0.00034 20.1 0.0 1.2 1 0 0 1 1 1 1 Tellurite resistance protein TehB Spermine_synth PF01564.17 KFY04179.1 - 0.0031 16.9 0.0 0.0067 15.8 0.0 1.4 1 1 0 1 1 1 1 Spermine/spermidine synthase domain Methyltransf_16 PF10294.9 KFY04179.1 - 0.0044 16.8 0.0 0.007 16.1 0.0 1.3 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_20 PF12147.8 KFY04179.1 - 0.0045 16.2 0.0 0.0058 15.8 0.0 1.1 1 0 0 1 1 1 1 Putative methyltransferase ApbA PF02558.16 KFY04179.1 - 0.0071 16.0 0.0 0.23 11.1 0.0 2.2 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA Methyltransf_15 PF09445.10 KFY04179.1 - 0.017 14.7 0.0 0.027 14.1 0.0 1.5 1 1 0 1 1 1 0 RNA cap guanine-N2 methyltransferase NodS PF05401.11 KFY04179.1 - 0.065 12.8 0.0 0.14 11.8 0.0 1.6 1 0 0 1 1 1 0 Nodulation protein S (NodS) Glyco_transf_4 PF13439.6 KFY04179.1 - 0.085 12.8 0.0 0.17 11.9 0.0 1.5 1 0 0 1 1 1 0 Glycosyltransferase Family 4 Methyltransf_18 PF12847.7 KFY04179.1 - 0.095 12.6 0.0 0.18 11.7 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase domain 3HCDH_N PF02737.18 KFY04179.1 - 0.11 12.4 0.1 0.25 11.2 0.1 1.6 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain adh_short PF00106.25 KFY04179.1 - 0.11 11.9 0.0 0.22 10.9 0.0 1.5 1 0 0 1 1 1 0 short chain dehydrogenase RrnaAD PF00398.20 KFY04179.1 - 0.13 11.3 0.0 0.19 10.7 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase TPMT PF05724.11 KFY04179.1 - 0.13 11.9 0.0 0.21 11.2 0.0 1.3 1 0 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) Pyr_redox_3 PF13738.6 KFY04180.1 - 9.8e-13 48.0 0.0 2.4e-12 46.7 0.0 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 KFY04180.1 - 4.6e-12 45.7 0.0 2.2e-09 36.9 0.0 2.9 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) FMO-like PF00743.19 KFY04180.1 - 1.1e-08 34.0 0.0 2.5e-08 32.8 0.0 1.5 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 KFY04180.1 - 2.7e-08 33.4 0.0 1.2e-06 28.0 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KFY04180.1 - 0.0001 21.6 0.1 0.00023 20.5 0.0 1.6 2 0 0 2 2 2 1 Thi4 family NAD_binding_9 PF13454.6 KFY04180.1 - 0.00034 20.6 0.1 0.08 12.9 0.0 3.0 3 1 0 3 3 3 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 KFY04180.1 - 0.0022 18.2 0.0 0.0071 16.5 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 KFY04180.1 - 0.0043 16.7 0.1 2.1 7.8 0.1 2.9 3 0 0 3 3 3 2 FAD dependent oxidoreductase HI0933_like PF03486.14 KFY04180.1 - 0.063 12.0 0.1 2.4 6.8 0.1 2.3 2 0 0 2 2 2 0 HI0933-like protein Gly_transf_sug PF04488.15 KFY04181.1 - 7.7e-22 77.8 0.1 1.8e-21 76.6 0.1 1.6 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif TcdA_TcdB PF12919.7 KFY04181.1 - 0.38 10.0 0.5 0.69 9.1 0.5 1.3 1 0 0 1 1 1 0 TcdA/TcdB catalytic glycosyltransferase domain DNA_pol_A_exo1 PF01612.20 KFY04182.1 - 4.8e-10 39.4 0.0 8.1e-10 38.7 0.0 1.3 1 0 0 1 1 1 1 3'-5' exonuclease p450 PF00067.22 KFY04183.1 - 4.5e-88 296.0 0.0 6.6e-88 295.5 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 MFS_1 PF07690.16 KFY04183.1 - 4.8e-22 78.4 25.6 1.5e-21 76.7 25.4 1.8 2 0 0 2 2 2 1 Major Facilitator Superfamily APH PF01636.23 KFY04183.1 - 4.7e-15 56.2 0.0 8.2e-15 55.4 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KFY04183.1 - 5e-06 26.2 0.1 9.5e-06 25.3 0.1 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase RIO1 PF01163.22 KFY04183.1 - 0.077 12.6 0.0 0.38 10.3 0.0 2.0 2 0 0 2 2 2 0 RIO1 family WD40 PF00400.32 KFY04184.1 - 1.7e-15 57.1 18.1 0.00088 20.0 0.4 6.3 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFY04184.1 - 2e-05 24.8 0.0 3.3 8.1 0.0 4.2 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Cwf_Cwc_15 PF04889.12 KFY04184.1 - 0.031 14.0 7.3 0.065 13.0 7.3 1.4 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Ge1_WD40 PF16529.5 KFY04184.1 - 0.036 13.0 0.0 0.49 9.3 0.0 2.5 3 0 0 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Nucleoporin_N PF08801.11 KFY04184.1 - 0.1 11.3 1.0 0.44 9.2 0.1 2.2 2 1 0 2 2 2 0 Nup133 N terminal like eIF2A PF08662.11 KFY04184.1 - 0.13 12.1 0.0 1.5 8.6 0.0 2.5 3 0 0 3 3 3 0 Eukaryotic translation initiation factor eIF2A Mg_trans_NIPA PF05653.14 KFY04185.1 - 2.3e-62 210.8 12.5 9.4e-61 205.5 8.2 2.1 2 0 0 2 2 2 2 Magnesium transporter NIPA LysE PF01810.18 KFY04185.1 - 0.00054 19.5 1.9 0.00054 19.5 1.9 3.0 3 1 1 4 4 4 2 LysE type translocator EamA PF00892.20 KFY04185.1 - 0.0015 18.7 2.2 0.0015 18.7 2.2 3.9 3 1 0 3 3 3 1 EamA-like transporter family SLC35F PF06027.12 KFY04185.1 - 0.0096 15.5 5.7 0.061 12.8 0.2 2.3 1 1 1 2 2 2 1 Solute carrier family 35 DUF418 PF04235.12 KFY04185.1 - 0.11 12.4 4.7 0.88 9.5 0.4 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF418) TssN PF17555.2 KFY04185.1 - 1.7 8.0 8.5 2.9 7.2 8.5 1.3 1 0 0 1 1 1 0 Type VI secretion system, TssN TPR_2 PF07719.17 KFY04186.1 - 0.0013 18.7 3.5 0.83 9.9 0.2 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 KFY04186.1 - 0.017 15.6 0.1 0.98 10.0 0.0 2.5 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.6 KFY04186.1 - 0.034 14.4 1.0 1.8 8.9 0.1 2.5 2 1 0 2 2 2 0 Tetratricopeptide repeat SPO22 PF08631.10 KFY04186.1 - 0.086 12.3 0.6 0.26 10.7 0.0 2.0 2 1 0 2 2 2 0 Meiosis protein SPO22/ZIP4 like TPR_1 PF00515.28 KFY04186.1 - 0.17 11.8 0.1 11 6.0 0.1 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.6 KFY04186.1 - 0.33 11.6 5.2 3 8.6 0.3 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_7 PF13176.6 KFY04186.1 - 0.99 9.6 2.8 5.3 7.3 0.1 3.2 4 0 0 4 4 4 0 Tetratricopeptide repeat MAP65_ASE1 PF03999.12 KFY04186.1 - 8.8 4.9 9.3 11 4.6 9.3 1.1 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) HMG_box PF00505.19 KFY04190.1 - 0.019 15.4 0.0 0.049 14.1 0.0 1.7 2 0 0 2 2 2 0 HMG (high mobility group) box RCR PF12273.8 KFY04190.1 - 0.052 14.2 1.1 0.12 13.0 1.1 1.6 1 0 0 1 1 1 0 Chitin synthesis regulation, resistance to Congo red HMG_box_2 PF09011.10 KFY04190.1 - 0.091 13.4 0.0 0.21 12.2 0.0 1.6 1 0 0 1 1 1 0 HMG-box domain CCDC106 PF15794.5 KFY04190.1 - 0.27 10.9 3.2 0.84 9.3 3.2 1.8 1 1 0 1 1 1 0 Coiled-coil domain-containing protein 106 RNA_pol_Rpb8 PF03870.15 KFY04195.1 - 1.5e-17 64.1 0.1 1.6e-17 64.0 0.1 1.0 1 0 0 1 1 1 1 RNA polymerase Rpb8 DUF4743 PF15916.5 KFY04196.1 - 1.5e-09 37.9 0.0 2.8e-09 37.0 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4743) NUDIX PF00293.28 KFY04196.1 - 4.2e-09 36.5 0.1 1.1e-08 35.2 0.1 1.6 1 0 0 1 1 1 1 NUDIX domain Sirohm_synth_C PF14823.6 KFY04196.1 - 0.11 12.2 0.0 0.2 11.3 0.0 1.4 1 0 0 1 1 1 0 Sirohaem biosynthesis protein C-terminal DUF775 PF05603.12 KFY04197.1 - 1.6e-58 197.6 0.0 1.8e-58 197.4 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF775) GDA1_CD39 PF01150.17 KFY04198.1 - 1.9e-108 362.9 0.0 2.7e-108 362.4 0.0 1.1 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family SKG6 PF08693.10 KFY04198.1 - 0.33 10.4 0.8 0.62 9.5 0.8 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Adeno_E3_CR2 PF02439.15 KFY04198.1 - 0.38 10.6 1.0 0.71 9.7 1.0 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 zf-RING_5 PF14634.6 KFY04199.1 - 5.9e-08 32.5 6.3 9.3e-08 31.9 6.3 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.6 KFY04199.1 - 9.3e-06 25.9 3.3 1.6e-05 25.1 3.3 1.3 1 0 0 1 1 1 1 Ring finger domain Prok-RING_4 PF14447.6 KFY04199.1 - 0.00029 20.6 3.7 0.00054 19.8 3.7 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_3 PF13920.6 KFY04199.1 - 0.00029 20.6 7.0 0.0005 19.9 7.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KFY04199.1 - 0.0015 18.4 7.2 0.0026 17.6 7.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 KFY04199.1 - 0.0047 16.9 3.0 0.011 15.7 3.0 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 KFY04199.1 - 0.0054 16.6 5.8 0.01 15.7 5.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) CENP-H PF05837.12 KFY04199.1 - 0.007 16.8 7.1 0.012 16.1 7.1 1.4 1 0 0 1 1 1 1 Centromere protein H (CENP-H) zf-rbx1 PF12678.7 KFY04199.1 - 0.018 15.3 2.4 0.032 14.5 2.4 1.5 1 0 0 1 1 1 0 RING-H2 zinc finger domain UPF0242 PF06785.11 KFY04199.1 - 0.019 15.0 5.8 0.028 14.5 5.8 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus zf-C3HC4_4 PF15227.6 KFY04199.1 - 0.04 14.1 5.4 0.081 13.1 5.4 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Exonuc_VII_L PF02601.15 KFY04199.1 - 0.05 13.2 3.2 0.07 12.7 3.2 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit zf-RING_6 PF14835.6 KFY04199.1 - 0.053 13.4 1.6 0.12 12.3 1.6 1.6 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-ANAPC11 PF12861.7 KFY04199.1 - 0.071 13.2 0.7 0.12 12.4 0.7 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger OmpH PF03938.14 KFY04199.1 - 0.084 13.2 12.1 0.12 12.7 12.1 1.1 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Drf_FH3 PF06367.16 KFY04199.1 - 0.086 12.5 5.3 0.14 11.8 5.3 1.3 1 0 0 1 1 1 0 Diaphanous FH3 Domain SKA1 PF07160.12 KFY04199.1 - 0.14 12.0 5.6 0.21 11.4 5.6 1.2 1 0 0 1 1 1 0 Spindle and kinetochore-associated protein 1 DUF4407 PF14362.6 KFY04199.1 - 0.14 11.5 6.3 0.2 11.0 6.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) MAD PF05557.13 KFY04199.1 - 0.16 10.3 9.7 0.22 9.9 9.7 1.1 1 0 0 1 1 1 0 Mitotic checkpoint protein zf-RING_4 PF14570.6 KFY04199.1 - 0.17 11.7 2.3 0.31 10.8 2.3 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-MIZ PF02891.20 KFY04199.1 - 0.28 11.0 3.9 0.5 10.2 3.9 1.4 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger Fmp27_WPPW PF10359.9 KFY04199.1 - 0.42 9.4 8.5 0.57 9.0 8.5 1.1 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain DNA_ligase_ZBD PF03119.16 KFY04199.1 - 0.42 10.7 4.3 3.1 7.9 0.1 2.5 2 0 0 2 2 2 0 NAD-dependent DNA ligase C4 zinc finger domain Spc7 PF08317.11 KFY04199.1 - 0.48 9.2 8.8 0.67 8.8 8.8 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein RNA_POL_M_15KD PF02150.16 KFY04199.1 - 0.8 9.6 6.9 1.2 9.1 1.8 2.8 2 1 1 3 3 3 0 RNA polymerases M/15 Kd subunit FapA PF03961.13 KFY04199.1 - 1.3 7.6 5.5 1.7 7.1 5.5 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A zf-C4H2 PF10146.9 KFY04199.1 - 3.3 8.0 9.8 0.078 13.3 1.3 2.1 2 0 0 2 2 2 0 Zinc finger-containing protein ALMT PF11744.8 KFY04199.1 - 3.4 6.4 6.5 5 5.8 6.5 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter DUF1272 PF06906.11 KFY04199.1 - 3.5 7.8 7.7 9.2 6.4 7.7 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1272) Fungal_trans PF04082.18 KFY04200.1 - 2.5e-19 69.4 0.0 4e-19 68.7 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KFY04200.1 - 4.1e-06 26.8 15.4 7.3e-06 26.0 15.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain KAR9 PF08580.10 KFY04200.1 - 0.57 8.7 6.5 0.87 8.1 6.5 1.1 1 0 0 1 1 1 0 Yeast cortical protein KAR9 ThiF PF00899.21 KFY04201.1 - 4.3e-19 68.8 0.0 1.4e-18 67.2 0.0 1.8 1 1 0 1 1 1 1 ThiF family E1_4HB PF16191.5 KFY04201.1 - 0.096 12.9 0.2 3.6 7.9 0.0 2.9 3 0 0 3 3 3 0 Ubiquitin-activating enzyme E1 four-helix bundle Clr2_transil PF16761.5 KFY04202.1 - 2.7e-22 79.4 2.5 4.9e-22 78.5 2.5 1.4 1 0 0 1 1 1 1 Transcription-silencing protein, cryptic loci regulator Clr2 Clr2 PF10383.9 KFY04202.1 - 1.2e-09 39.0 0.7 1e-08 36.1 0.2 2.4 2 1 0 2 2 2 1 Transcription-silencing protein Clr2 SNF2_N PF00176.23 KFY04203.1 - 5.8e-57 193.0 0.0 6.4e-56 189.6 0.0 2.0 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KFY04203.1 - 8.7e-17 61.5 0.1 5.4e-16 58.9 0.1 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain HDA2-3 PF11496.8 KFY04203.1 - 9.2e-08 31.6 0.0 3.1e-07 29.9 0.0 1.8 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 ResIII PF04851.15 KFY04203.1 - 1.7e-06 28.2 0.0 5.6e-06 26.5 0.0 1.9 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit PHD PF00628.29 KFY04203.1 - 0.0048 16.7 21.5 0.013 15.4 9.1 3.3 1 1 1 2 2 2 1 PHD-finger DEAD PF00270.29 KFY04203.1 - 0.0079 16.0 0.0 0.82 9.4 0.0 2.5 1 1 0 1 1 1 1 DEAD/DEAH box helicase Zf_RING PF16744.5 KFY04203.1 - 0.24 11.5 14.8 8.1 6.6 5.8 2.6 1 1 1 2 2 2 0 KIAA1045 RING finger MARVEL PF01284.23 KFY04204.1 - 7.6e-06 26.0 6.7 1e-05 25.6 6.2 1.6 1 1 0 1 1 1 1 Membrane-associating domain ABC2_membrane_5 PF13346.6 KFY04204.1 - 0.015 14.9 0.7 0.015 14.9 0.7 1.7 2 0 0 2 2 2 0 ABC-2 family transporter protein LYRIC PF15686.5 KFY04204.1 - 0.075 12.6 0.1 0.19 11.3 0.1 1.6 1 0 0 1 1 1 0 Lysine-rich CEACAM1 co-isolated protein family Abhydrolase_9_N PF15420.6 KFY04204.1 - 0.29 11.1 3.4 0.37 10.8 1.8 1.8 2 0 0 2 2 2 0 Alpha/beta-hydrolase family N-terminus DUF4059 PF13268.6 KFY04204.1 - 0.49 10.8 8.3 2.1 8.8 0.2 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF4059) DUF4381 PF14316.6 KFY04204.1 - 0.84 9.9 2.6 23 5.2 0.8 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4381) Pkinase_Tyr PF07714.17 KFY04208.1 - 4.4e-14 52.4 0.0 7e-14 51.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 KFY04208.1 - 1.3e-13 50.9 0.3 2.6e-13 49.9 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain Unstab_antitox PF09720.10 KFY04208.1 - 0.047 13.7 5.0 0.15 12.1 0.7 2.7 2 0 0 2 2 2 0 Putative addiction module component Nbl1_Borealin_N PF10444.9 KFY04208.1 - 0.31 10.7 4.5 1.7 8.3 0.1 2.8 3 0 0 3 3 3 0 Nbl1 / Borealin N terminal DUF4644 PF15486.6 KFY04208.1 - 7.4 6.3 10.4 0.25 11.1 0.5 2.8 2 1 1 3 3 3 0 Domain of unknown function (DUF4644) TolB_like PF15869.5 KFY04209.1 - 0.17 11.1 0.0 0.29 10.3 0.0 1.2 1 0 0 1 1 1 0 TolB-like 6-blade propeller-like Glyco_trans_2_3 PF13632.6 KFY04213.1 - 2.6e-52 177.6 1.3 2.6e-52 177.6 1.3 2.5 2 0 0 2 2 2 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.26 KFY04213.1 - 0.0022 17.8 0.0 0.016 15.0 0.0 2.2 2 0 0 2 2 2 1 Glycosyl transferase family 2 Phage_GPO PF05929.11 KFY04217.1 - 0.00052 19.7 3.9 0.00052 19.7 3.9 2.9 1 1 2 3 3 3 1 Phage capsid scaffolding protein (GPO) serine peptidase TPR_MLP1_2 PF07926.12 KFY04217.1 - 1.2 9.2 46.4 0.76 9.8 14.6 3.8 2 1 2 4 4 4 0 TPR/MLP1/MLP2-like protein FAM76 PF16046.5 KFY04217.1 - 1.7 8.0 39.5 0.044 13.1 10.5 2.2 1 1 1 2 2 2 0 FAM76 protein DUF1664 PF07889.12 KFY04217.1 - 7.9 6.5 19.4 7.3 6.7 2.6 3.5 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) Ank_2 PF12796.7 KFY04219.1 - 4.6e-58 193.8 22.6 3e-12 47.0 1.4 7.4 2 2 4 7 7 7 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KFY04219.1 - 1.3e-45 153.2 18.5 4.7e-10 39.8 0.8 8.5 5 1 2 8 8 8 7 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFY04219.1 - 4.1e-42 137.3 17.5 0.00098 19.4 0.0 12.4 12 0 0 12 12 12 9 Ankyrin repeat Ank PF00023.30 KFY04219.1 - 2.9e-39 131.8 39.1 4.2e-05 23.8 0.2 12.2 13 0 0 13 13 13 8 Ankyrin repeat Ank_5 PF13857.6 KFY04219.1 - 2.7e-33 113.6 23.0 8.1e-08 32.4 1.1 9.6 5 1 5 11 11 11 7 Ankyrin repeats (many copies) DUF3447 PF11929.8 KFY04219.1 - 0.043 13.8 0.0 23 5.0 0.0 3.9 2 1 2 4 4 4 0 Domain of unknown function (DUF3447) F-box-like PF12937.7 KFY04220.1 - 0.0065 16.3 1.2 0.013 15.3 1.2 1.6 1 0 0 1 1 1 1 F-box-like VD10_N PF08476.10 KFY04221.1 - 0.23 11.2 0.6 9.1 6.0 0.1 3.1 3 0 0 3 3 3 0 Viral D10 N-terminal DUF1388 PF07142.12 KFY04222.1 - 0.00023 21.0 14.3 0.0023 17.9 4.0 8.2 7 2 3 10 10 10 5 Repeat of unknown function (DUF1388) cobW PF02492.19 KFY04228.1 - 1.6e-46 158.1 2.2 1.1e-34 119.6 0.1 2.3 1 1 1 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.14 KFY04228.1 - 3.7e-21 74.9 0.1 2.5e-15 56.2 0.0 2.8 2 0 0 2 2 2 2 Cobalamin synthesis protein cobW C-terminal domain MobB PF03205.14 KFY04228.1 - 0.0012 18.8 0.0 0.0031 17.4 0.0 1.7 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B TsaE PF02367.17 KFY04228.1 - 0.015 15.3 0.1 0.041 13.9 0.1 1.7 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Peroxin-22 PF12827.7 KFY04228.1 - 0.059 13.3 0.0 0.4 10.6 0.0 2.3 2 0 0 2 2 2 0 Peroxisomal biogenesis protein family AAA_16 PF13191.6 KFY04228.1 - 0.075 13.4 0.0 0.23 11.8 0.0 1.8 1 0 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.6 KFY04228.1 - 0.088 13.1 0.0 0.4 10.9 0.0 2.1 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 KFY04228.1 - 0.1 13.2 0.9 0.74 10.4 0.0 2.6 3 0 0 3 3 2 0 AAA domain Viral_helicase1 PF01443.18 KFY04228.1 - 0.12 12.1 0.0 0.24 11.1 0.0 1.5 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_29 PF13555.6 KFY04228.1 - 0.12 12.2 0.3 0.26 11.1 0.3 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_33 PF13671.6 KFY04228.1 - 0.16 12.1 0.0 0.73 10.0 0.0 2.1 1 1 0 1 1 1 0 AAA domain Pex14_N PF04695.13 KFY04228.1 - 5.8 7.5 8.7 20 5.8 0.8 2.3 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region GLEYA PF10528.9 KFY04229.1 - 5.3e-27 94.1 0.4 5.3e-27 94.1 0.4 1.7 2 0 0 2 2 2 1 GLEYA domain PA14 PF07691.12 KFY04229.1 - 4.6e-08 33.0 0.0 8.9e-08 32.1 0.0 1.5 1 0 0 1 1 1 1 PA14 domain Stig1 PF04885.13 KFY04229.1 - 0.0062 17.0 23.4 0.0097 16.4 23.4 1.2 1 0 0 1 1 1 1 Stigma-specific protein, Stig1 GMC_oxred_N PF00732.19 KFY04230.1 - 4.4e-30 105.1 0.0 4.5e-26 91.9 0.0 2.8 1 1 1 2 2 2 2 GMC oxidoreductase GMC_oxred_C PF05199.13 KFY04230.1 - 5.7e-28 98.3 0.0 9e-28 97.6 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.6 KFY04230.1 - 1.2e-05 25.4 1.1 3.7e-05 23.9 1.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 KFY04230.1 - 0.0016 17.6 1.1 0.0026 16.9 1.1 1.3 1 0 0 1 1 1 1 FAD binding domain ApbA PF02558.16 KFY04230.1 - 0.0025 17.5 0.2 0.0054 16.4 0.2 1.6 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Pyr_redox_2 PF07992.14 KFY04230.1 - 0.0027 17.0 0.1 0.0057 15.9 0.0 1.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KFY04230.1 - 0.015 14.1 0.4 0.022 13.5 0.4 1.2 1 0 0 1 1 1 0 HI0933-like protein Lycopene_cycl PF05834.12 KFY04230.1 - 0.023 13.7 0.0 0.032 13.3 0.0 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein Pyr_redox_3 PF13738.6 KFY04230.1 - 0.12 11.6 2.8 2.2 7.5 0.0 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase PhoPQ_related PF10142.9 KFY04230.1 - 0.22 10.2 0.0 0.37 9.4 0.0 1.3 1 0 0 1 1 1 0 PhoPQ-activated pathogenicity-related protein ADH_zinc_N PF00107.26 KFY04231.1 - 5.9e-05 23.0 0.0 0.00011 22.1 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Zn_clus PF00172.18 KFY04232.1 - 4.3e-05 23.6 7.0 7.8e-05 22.7 7.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KFY04232.1 - 0.0083 15.2 0.0 0.016 14.2 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain MFS_1 PF07690.16 KFY04233.1 - 1.4e-21 76.8 49.0 1.4e-21 76.8 49.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily AMP-binding PF00501.28 KFY04234.1 - 1.1e-210 699.6 0.0 2.1e-71 240.7 0.0 3.2 3 0 0 3 3 3 3 AMP-binding enzyme Condensation PF00668.20 KFY04234.1 - 8e-134 446.7 0.0 1.4e-33 116.3 0.0 4.8 4 1 0 4 4 4 4 Condensation domain PP-binding PF00550.25 KFY04234.1 - 6.8e-32 109.6 0.1 5e-12 46.0 0.0 3.7 3 0 0 3 3 3 3 Phosphopantetheine attachment site AMP-binding_C PF13193.6 KFY04234.1 - 8e-05 23.5 0.0 0.67 11.0 0.0 4.2 3 0 0 3 3 3 2 AMP-binding enzyme C-terminal domain FAD_binding_4 PF01565.23 KFY04236.1 - 2.1e-22 79.4 0.5 2.1e-22 79.4 0.5 2.5 3 0 0 3 3 3 1 FAD binding domain FAD_binding_3 PF01494.19 KFY04236.1 - 4e-15 55.9 1.2 3.7e-09 36.3 0.7 2.6 2 0 0 2 2 2 2 FAD binding domain FAD_binding_2 PF00890.24 KFY04236.1 - 1.4e-08 34.2 0.3 3e-08 33.2 0.3 1.5 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 KFY04236.1 - 2.4e-07 30.3 0.7 0.0018 17.6 0.1 2.6 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KFY04236.1 - 1.1e-06 28.5 4.6 0.015 14.9 0.1 2.4 1 1 0 2 2 2 2 FAD dependent oxidoreductase BBE PF08031.12 KFY04236.1 - 2.9e-06 27.3 0.0 6.7e-06 26.1 0.0 1.7 1 0 0 1 1 1 1 Berberine and berberine like HI0933_like PF03486.14 KFY04236.1 - 5.8e-06 25.3 0.6 0.0008 18.2 0.7 2.2 2 0 0 2 2 2 2 HI0933-like protein FAD_oxidored PF12831.7 KFY04236.1 - 9e-05 22.0 0.1 0.00014 21.4 0.1 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 KFY04236.1 - 0.0018 17.6 0.4 0.0048 16.2 0.4 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 KFY04236.1 - 0.0034 16.5 0.5 0.0059 15.7 0.5 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A NAD_binding_8 PF13450.6 KFY04236.1 - 0.0072 16.5 0.2 0.0072 16.5 0.2 2.7 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.24 KFY04236.1 - 0.0078 15.5 0.2 1.6 7.9 0.0 2.2 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase AlaDh_PNT_C PF01262.21 KFY04236.1 - 0.011 15.0 0.5 0.028 13.7 0.5 1.6 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Thi4 PF01946.17 KFY04236.1 - 0.013 14.8 0.1 0.025 13.8 0.1 1.4 1 0 0 1 1 1 0 Thi4 family Pyr_redox PF00070.27 KFY04236.1 - 0.018 15.6 0.4 1.3 9.6 0.5 2.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KFY04236.1 - 0.081 12.0 0.4 0.15 11.1 0.4 1.4 1 0 0 1 1 1 0 Lycopene cyclase protein 2OG-Fe_Oxy_2 PF10014.9 KFY04237.1 - 2.9e-51 174.0 0.5 3.5e-51 173.7 0.5 1.1 1 0 0 1 1 1 1 2OG-Fe dioxygenase HAD_2 PF13419.6 KFY04238.1 - 2.4e-12 47.3 0.0 6.2e-12 46.0 0.0 1.6 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KFY04238.1 - 0.011 16.0 0.0 0.2 11.9 0.0 2.3 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase Aldolase_II PF00596.21 KFY04239.1 - 2.3e-43 148.3 0.1 2.9e-43 148.0 0.1 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain FAD_binding_3 PF01494.19 KFY04240.1 - 3.3e-14 52.9 8.2 2.4e-10 40.2 1.7 2.9 2 1 0 2 2 2 2 FAD binding domain FAD_binding_2 PF00890.24 KFY04240.1 - 2.4e-05 23.6 0.5 4.8e-05 22.6 0.5 1.4 1 0 0 1 1 1 1 FAD binding domain AlaDh_PNT_C PF01262.21 KFY04240.1 - 0.00032 20.1 0.1 0.00062 19.1 0.1 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox_2 PF07992.14 KFY04240.1 - 0.0036 16.6 0.5 0.0036 16.6 0.5 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KFY04240.1 - 0.0059 16.2 1.4 0.014 15.0 0.4 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_oxidored PF12831.7 KFY04240.1 - 0.0077 15.6 0.5 0.012 15.0 0.5 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KFY04240.1 - 0.013 15.8 0.5 0.035 14.3 0.5 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 KFY04240.1 - 0.016 13.9 0.3 0.03 13.0 0.3 1.4 1 0 0 1 1 1 0 HI0933-like protein GIDA PF01134.22 KFY04240.1 - 0.031 13.4 0.4 0.031 13.4 0.4 1.8 2 0 0 2 2 2 0 Glucose inhibited division protein A Pyr_redox PF00070.27 KFY04240.1 - 0.11 13.0 0.6 0.35 11.4 0.6 1.9 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KFY04240.1 - 0.15 11.1 2.0 18 4.2 0.0 2.9 3 0 0 3 3 3 0 Lycopene cyclase protein AMP-binding PF00501.28 KFY04241.1 - 1e-64 218.7 0.0 1.4e-64 218.2 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme Condensation PF00668.20 KFY04241.1 - 2.1e-22 79.4 0.0 6.1e-22 77.9 0.0 1.6 1 1 0 1 1 1 1 Condensation domain PP-binding PF00550.25 KFY04241.1 - 8e-11 42.1 0.1 2e-10 40.9 0.1 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site Trypsin PF00089.26 KFY04242.1 - 5.9e-34 117.8 0.1 6.7e-34 117.6 0.1 1.0 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.6 KFY04242.1 - 2.6e-10 41.4 0.1 4.3e-10 40.7 0.1 1.4 1 1 0 1 1 1 1 Trypsin-like peptidase domain PH PF00169.29 KFY04248.1 - 1e-06 29.2 0.5 3.2e-06 27.6 0.5 1.9 1 1 0 1 1 1 1 PH domain PH_9 PF15410.6 KFY04248.1 - 9.2e-05 22.8 0.1 0.00019 21.8 0.1 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain Nucleoside_tran PF01733.18 KFY04249.1 - 1.9e-38 132.6 12.1 2.2e-24 86.4 3.4 2.7 3 0 0 3 3 3 2 Nucleoside transporter A_deaminase PF00962.22 KFY04250.1 - 1e-40 140.1 0.0 1.6e-40 139.5 0.0 1.3 1 1 0 1 1 1 1 Adenosine/AMP deaminase PRP1_N PF06424.12 KFY04254.1 - 0.00033 21.1 9.4 0.00033 21.1 9.4 2.0 2 0 0 2 2 2 1 PRP1 splicing factor, N-terminal Nucleo_P87 PF07267.11 KFY04254.1 - 0.79 8.5 19.1 0.28 10.0 15.7 1.9 2 0 0 2 2 2 0 Nucleopolyhedrovirus capsid protein P87 NOA36 PF06524.12 KFY04254.1 - 1.8 7.8 9.6 5 6.4 9.6 1.7 1 0 0 1 1 1 0 NOA36 protein Topoisom_bac PF01131.20 KFY04258.1 - 1.7e-05 24.0 0.0 2.2e-05 23.6 0.0 1.1 1 0 0 1 1 1 1 DNA topoisomerase Stb3 PF10330.9 KFY04260.1 - 3.5e-39 132.7 0.0 5.9e-39 132.0 0.0 1.4 1 0 0 1 1 1 1 Putative Sin3 binding protein MatE PF01554.18 KFY04261.1 - 1.3e-52 177.7 24.8 2.4e-35 121.6 6.3 2.3 2 0 0 2 2 2 2 MatE Polysacc_synt_C PF14667.6 KFY04261.1 - 9.1 6.3 39.6 0.014 15.4 16.1 4.1 3 2 0 3 3 3 0 Polysaccharide biosynthesis C-terminal domain DegT_DnrJ_EryC1 PF01041.17 KFY04262.1 - 3.5e-66 224.0 0.0 3.9e-66 223.8 0.0 1.0 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family DUF3454 PF11936.8 KFY04263.1 - 0.12 12.8 2.4 0.44 11.0 2.4 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF3454) CCDC-167 PF15188.6 KFY04263.1 - 0.46 10.9 3.4 0.94 9.9 0.4 2.3 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 167 DUF4149 PF13664.6 KFY04264.1 - 2.8e-25 88.6 2.9 2.8e-25 88.6 2.9 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4149) Ku_N PF03731.15 KFY04265.1 - 1.9e-13 50.7 0.0 2.3e-13 50.4 0.0 1.1 1 0 0 1 1 1 1 Ku70/Ku80 N-terminal alpha/beta domain VWA PF00092.28 KFY04265.1 - 7.4e-06 26.3 0.3 1.5e-05 25.3 0.3 1.7 1 1 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 KFY04265.1 - 0.051 14.2 0.1 0.13 12.9 0.1 1.7 1 1 0 1 1 1 0 von Willebrand factor type A domain Amino_oxidase PF01593.24 KFY04271.1 - 3.2e-39 135.5 0.0 1.1e-37 130.4 0.0 2.5 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase Ank_4 PF13637.6 KFY04271.1 - 1.9e-11 44.2 0.1 7.8e-06 26.3 0.0 2.8 1 1 1 2 2 2 2 Ankyrin repeats (many copies) NAD_binding_8 PF13450.6 KFY04271.1 - 4.7e-09 36.3 0.2 1.1e-08 35.1 0.2 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Ank_2 PF12796.7 KFY04271.1 - 1.1e-08 35.5 0.0 3.9e-08 33.8 0.0 2.0 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) DAO PF01266.24 KFY04271.1 - 6.2e-07 29.3 0.0 1.2e-06 28.4 0.0 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase Ank_5 PF13857.6 KFY04271.1 - 1.8e-06 28.1 0.4 7e-05 23.0 0.2 3.3 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 KFY04271.1 - 4.3e-05 23.8 5.4 0.0051 17.2 0.0 3.7 4 0 0 4 4 4 1 Ankyrin repeat Pyr_redox_2 PF07992.14 KFY04271.1 - 0.00024 20.4 0.0 0.00043 19.6 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KFY04271.1 - 0.001 19.6 0.1 0.0033 18.0 0.1 1.9 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Ank_3 PF13606.6 KFY04271.1 - 0.0013 19.0 0.2 1.5 9.6 0.0 3.7 3 0 0 3 3 3 1 Ankyrin repeat HI0933_like PF03486.14 KFY04271.1 - 0.0029 16.4 0.0 0.0064 15.2 0.0 1.5 1 0 0 1 1 1 1 HI0933-like protein FAD_binding_3 PF01494.19 KFY04271.1 - 0.0046 16.3 0.2 0.0099 15.2 0.2 1.4 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.17 KFY04271.1 - 0.0049 16.1 0.0 0.01 15.1 0.0 1.5 1 0 0 1 1 1 1 Thi4 family AlaDh_PNT_C PF01262.21 KFY04271.1 - 0.022 14.1 0.0 0.043 13.1 0.0 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain 3HCDH_N PF02737.18 KFY04271.1 - 0.037 13.9 0.0 0.12 12.2 0.0 1.9 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_9 PF13454.6 KFY04271.1 - 0.048 13.7 0.0 0.12 12.3 0.0 1.7 1 0 0 1 1 1 0 FAD-NAD(P)-binding FAD_binding_2 PF00890.24 KFY04271.1 - 0.06 12.4 0.1 0.12 11.4 0.1 1.4 1 0 0 1 1 1 0 FAD binding domain FAD_oxidored PF12831.7 KFY04271.1 - 0.066 12.5 0.0 0.13 11.6 0.0 1.5 1 0 0 1 1 1 0 FAD dependent oxidoreductase NAD_binding_7 PF13241.6 KFY04271.1 - 0.13 12.7 0.0 0.74 10.3 0.0 2.2 2 0 0 2 2 2 0 Putative NAD(P)-binding FMO-like PF00743.19 KFY04271.1 - 0.17 10.3 0.0 0.26 9.7 0.0 1.2 1 0 0 1 1 1 0 Flavin-binding monooxygenase-like GIDA PF01134.22 KFY04271.1 - 0.17 10.9 0.1 0.35 9.9 0.1 1.5 1 0 0 1 1 1 0 Glucose inhibited division protein A Translin PF01997.16 KFY04273.1 - 8.7e-51 172.8 0.0 1e-50 172.6 0.0 1.0 1 0 0 1 1 1 1 Translin family PIG-F PF06699.11 KFY04274.1 - 4.9e-53 180.0 5.2 7.8e-53 179.3 5.2 1.3 1 0 0 1 1 1 1 GPI biosynthesis protein family Pig-F Gly-zipper_YMGG PF13441.6 KFY04274.1 - 0.66 9.8 11.9 0.31 10.8 1.8 2.6 2 0 0 2 2 2 0 YMGG-like Gly-zipper Gly-zipper_Omp PF13488.6 KFY04274.1 - 2.7 8.1 13.7 4.4 7.4 3.0 2.6 2 0 0 2 2 2 0 Glycine zipper Tubulin PF00091.25 KFY04275.1 - 7e-68 228.7 0.0 1.1e-67 228.1 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 KFY04275.1 - 1.5e-45 154.4 0.1 3.2e-45 153.3 0.1 1.6 1 0 0 1 1 1 1 Tubulin C-terminal domain Mito_carr PF00153.27 KFY04275.1 - 1.3e-39 134.0 2.3 1.1e-16 60.5 0.1 4.1 4 0 0 4 4 4 3 Mitochondrial carrier protein GDPD PF03009.17 KFY04275.1 - 2.4e-32 112.7 0.0 4.5e-32 111.8 0.0 1.5 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family Misat_Tub_SegII PF10644.9 KFY04275.1 - 1.2e-06 28.8 0.0 2.3e-06 27.9 0.0 1.4 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain GDPD_2 PF13653.6 KFY04275.1 - 4.3e-05 23.8 1.7 7.3e-05 23.1 0.3 2.3 2 0 0 2 2 2 1 Glycerophosphoryl diester phosphodiesterase family Ribosomal_L22e PF01776.17 KFY04276.1 - 2.4e-46 156.6 1.3 2.9e-46 156.3 1.3 1.0 1 0 0 1 1 1 1 Ribosomal L22e protein family ketoacyl-synt PF00109.26 KFY04283.1 - 2.2e-74 250.3 0.0 3.6e-74 249.5 0.0 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.10 KFY04283.1 - 4.2e-53 179.9 0.1 9.6e-53 178.8 0.1 1.7 1 0 0 1 1 1 1 KR domain PS-DH PF14765.6 KFY04283.1 - 1.8e-47 162.1 0.0 3.1e-46 158.0 0.0 2.2 1 1 0 1 1 1 1 Polyketide synthase dehydratase Acyl_transf_1 PF00698.21 KFY04283.1 - 2.3e-45 155.5 0.0 3.8e-45 154.8 0.0 1.3 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 KFY04283.1 - 2.6e-30 104.9 1.4 1e-29 102.9 0.0 2.7 3 0 0 3 3 2 1 Beta-ketoacyl synthase, C-terminal domain Methyltransf_12 PF08242.12 KFY04283.1 - 1.8e-21 76.7 0.0 7.9e-21 74.7 0.0 2.2 2 0 0 2 2 1 1 Methyltransferase domain KAsynt_C_assoc PF16197.5 KFY04283.1 - 1.7e-16 60.6 0.0 4.7e-16 59.2 0.0 1.7 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension Methyltransf_25 PF13649.6 KFY04283.1 - 1.8e-16 60.6 0.0 7.2e-16 58.7 0.0 2.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KFY04283.1 - 1.3e-15 57.8 0.0 5.2e-15 55.9 0.0 2.1 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KFY04283.1 - 1.9e-15 57.1 0.0 4.9e-15 55.8 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KFY04283.1 - 2.4e-15 56.6 0.1 8e-15 54.9 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain adh_short PF00106.25 KFY04283.1 - 1.5e-13 50.6 0.3 8.5e-13 48.2 0.1 2.3 2 0 0 2 2 2 1 short chain dehydrogenase Ubie_methyltran PF01209.18 KFY04283.1 - 3.6e-10 39.6 0.0 7.2e-10 38.6 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_16 PF10294.9 KFY04283.1 - 1.9e-05 24.5 0.0 4.2e-05 23.4 0.0 1.5 1 0 0 1 1 1 1 Lysine methyltransferase Thiolase_N PF00108.23 KFY04283.1 - 2.6e-05 23.7 0.0 5.3e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain Methyltransf_33 PF10017.9 KFY04283.1 - 0.0066 15.6 0.0 0.015 14.4 0.0 1.5 1 0 0 1 1 1 1 Histidine-specific methyltransferase, SAM-dependent Methyltransf_8 PF05148.15 KFY04283.1 - 0.01 15.7 0.0 0.021 14.7 0.0 1.4 1 0 0 1 1 1 0 Hypothetical methyltransferase RrnaAD PF00398.20 KFY04283.1 - 0.077 12.0 0.0 0.17 10.9 0.0 1.5 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase NodS PF05401.11 KFY04283.1 - 0.12 11.9 0.0 0.24 11.0 0.0 1.3 1 0 0 1 1 1 0 Nodulation protein S (NodS) ACP_syn_III PF08545.10 KFY04283.1 - 0.13 12.2 0.6 0.47 10.3 0.4 2.1 2 0 0 2 2 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III GDP_Man_Dehyd PF16363.5 KFY04283.1 - 0.17 11.3 0.0 0.27 10.6 0.0 1.2 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase NNMT_PNMT_TEMT PF01234.17 KFY04283.1 - 0.2 10.8 0.0 3 7.0 0.0 2.2 2 0 0 2 2 2 0 NNMT/PNMT/TEMT family DUF2439 PF10382.9 KFY04291.1 - 4.4e-27 94.2 0.1 9.2e-27 93.2 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2439) PI3_PI4_kinase PF00454.27 KFY04292.1 - 2e-53 181.8 0.0 3.5e-53 181.0 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FAT PF02259.23 KFY04292.1 - 2.2e-41 142.2 6.4 4.1e-41 141.3 6.4 1.5 1 0 0 1 1 1 1 FAT domain UME PF08064.13 KFY04292.1 - 3.1e-33 113.7 0.4 1e-31 108.9 0.1 3.1 2 0 0 2 2 2 1 UME (NUC010) domain TPR_19 PF14559.6 KFY04292.1 - 0.0023 18.4 2.6 0.041 14.4 0.0 3.9 5 0 0 5 5 5 1 Tetratricopeptide repeat HEAT_EZ PF13513.6 KFY04292.1 - 0.12 12.9 0.1 1.1 9.8 0.0 2.9 2 0 0 2 2 2 0 HEAT-like repeat COX16 PF14138.6 KFY04293.1 - 3.7e-34 117.1 0.1 4.8e-34 116.7 0.1 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein COX16 OppC_N PF12911.7 KFY04293.1 - 0.076 13.0 0.0 0.11 12.5 0.0 1.2 1 0 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C Acetyltransf_1 PF00583.25 KFY04294.1 - 1.2e-10 41.7 0.0 1.5e-10 41.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KFY04294.1 - 2.3e-08 34.0 0.0 3.4e-08 33.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KFY04294.1 - 1.2e-06 28.8 0.0 1.9e-06 28.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KFY04294.1 - 5.2e-05 23.1 0.0 8.6e-05 22.4 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein PanZ PF12568.8 KFY04294.1 - 0.0072 16.0 0.0 0.015 15.0 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain, PanZ Acetyltransf_9 PF13527.7 KFY04294.1 - 0.021 14.9 0.0 0.033 14.3 0.0 1.4 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 KFY04294.1 - 0.052 13.7 0.0 0.062 13.4 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 KFY04294.1 - 0.09 12.9 0.0 0.18 11.9 0.0 1.5 1 1 0 1 1 1 0 GCN5-related N-acetyl-transferase BcrAD_BadFG PF01869.20 KFY04295.1 - 1e-16 61.2 0.4 1.7e-16 60.5 0.4 1.3 1 0 0 1 1 1 1 BadF/BadG/BcrA/BcrD ATPase family SIS_2 PF13580.6 KFY04295.1 - 9.1e-05 22.5 0.2 0.0013 18.8 0.1 3.1 2 1 0 2 2 2 1 SIS domain SIS PF01380.22 KFY04295.1 - 0.00048 20.0 0.6 0.0026 17.6 0.0 2.4 2 1 0 2 2 2 1 SIS domain UNC-93 PF05978.16 KFY04296.1 - 2.3e-08 33.9 5.7 2.3e-08 33.9 5.7 2.0 2 0 0 2 2 2 1 Ion channel regulatory protein UNC-93 MFS_1 PF07690.16 KFY04296.1 - 2.3e-08 33.3 39.8 2.3e-08 33.3 39.8 1.9 1 1 0 1 1 1 1 Major Facilitator Superfamily Beta-lactamase PF00144.24 KFY04297.1 - 9.4e-52 176.3 0.0 1.2e-51 175.9 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase Peptidase_S11 PF00768.20 KFY04297.1 - 0.00053 19.5 0.8 0.0029 17.1 0.2 2.3 2 1 1 3 3 3 1 D-alanyl-D-alanine carboxypeptidase Beta-lactamase2 PF13354.6 KFY04297.1 - 0.048 13.3 0.0 0.094 12.3 0.0 1.4 1 0 0 1 1 1 0 Beta-lactamase enzyme family DUF218 PF02698.17 KFY04298.1 - 5.2e-23 81.5 0.0 6.8e-23 81.1 0.0 1.2 1 0 0 1 1 1 1 DUF218 domain DUF1866 PF08952.11 KFY04298.1 - 0.15 11.9 0.0 0.23 11.3 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1866) Methyltransf_11 PF08241.12 KFY04300.1 - 7.4e-12 45.8 0.0 1.2e-11 45.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KFY04300.1 - 9.3e-12 45.5 0.0 2.1e-11 44.4 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KFY04300.1 - 1.5e-08 34.6 0.0 1.9e-08 34.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KFY04300.1 - 8.1e-06 26.5 0.0 1.2e-05 25.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KFY04300.1 - 0.00099 18.7 0.0 0.0017 17.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain N2227 PF07942.12 KFY04300.1 - 0.007 15.6 0.0 1.3 8.2 0.0 2.2 2 0 0 2 2 2 2 N2227-like protein Methyltransf_32 PF13679.6 KFY04300.1 - 0.046 13.7 0.0 0.057 13.4 0.0 1.1 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_8 PF05148.15 KFY04300.1 - 0.047 13.5 0.0 0.74 9.6 0.0 2.5 1 1 0 1 1 1 0 Hypothetical methyltransferase Epimerase PF01370.21 KFY04301.1 - 4.5e-08 32.8 0.1 1.2e-06 28.1 0.0 2.7 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 KFY04301.1 - 1.4e-06 27.7 0.0 2e-06 27.1 0.0 1.2 1 0 0 1 1 1 1 Male sterility protein adh_short PF00106.25 KFY04301.1 - 0.0043 16.5 0.2 2.9 7.3 0.0 2.8 2 1 1 3 3 3 2 short chain dehydrogenase 3Beta_HSD PF01073.19 KFY04301.1 - 0.0054 15.8 0.0 0.011 14.7 0.0 1.5 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 KFY04301.1 - 0.014 14.8 0.0 0.16 11.3 0.0 2.1 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase APH PF01636.23 KFY04302.1 - 4.2e-14 53.1 0.0 8.1e-14 52.1 0.0 1.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 KFY04302.1 - 9.5e-05 22.1 0.0 0.00015 21.5 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase RIO1 PF01163.22 KFY04302.1 - 0.0027 17.3 0.0 0.091 12.4 0.0 2.1 2 0 0 2 2 2 1 RIO1 family AIRC PF00731.20 KFY04303.1 - 1.3e-57 193.6 1.4 3e-57 192.3 1.4 1.7 1 0 0 1 1 1 1 AIR carboxylase ATP-grasp PF02222.22 KFY04303.1 - 5.6e-54 182.3 0.0 1.1e-53 181.3 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain PurK_C PF17769.1 KFY04303.1 - 5.8e-20 70.7 0.1 1.5e-19 69.4 0.1 1.8 1 0 0 1 1 1 1 Phosphoribosylaminoimidazole carboxylase C-terminal domain CPSase_L_D2 PF02786.17 KFY04303.1 - 3e-07 30.1 0.0 5.6e-07 29.3 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Dala_Dala_lig_C PF07478.13 KFY04303.1 - 0.01 15.4 0.0 0.079 12.5 0.0 2.1 1 1 0 1 1 1 0 D-ala D-ala ligase C-terminus Radical_SAM PF04055.21 KFY04303.1 - 0.012 16.0 0.0 4.2 7.7 0.0 2.4 2 0 0 2 2 2 0 Radical SAM superfamily 2-Hacid_dh_C PF02826.19 KFY04303.1 - 0.14 11.5 0.0 0.4 10.0 0.0 1.7 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2OG-FeII_Oxy_2 PF13532.6 KFY04304.1 - 5.8e-23 82.1 0.0 1.9e-22 80.4 0.0 1.9 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily AMP-binding PF00501.28 KFY04305.1 - 6.9e-78 262.1 0.0 8.4e-78 261.8 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KFY04305.1 - 4.2e-12 46.9 0.2 1.1e-11 45.6 0.1 1.8 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain Git3 PF11710.8 KFY04310.1 - 0.00016 21.5 1.4 0.00018 21.3 1.4 1.0 1 0 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 CS PF04969.16 KFY04316.1 - 1.9e-17 64.0 0.1 1.5e-16 61.1 0.0 2.1 2 0 0 2 2 2 1 CS domain MAT1 PF06391.13 KFY04317.1 - 1.8e-35 122.6 15.4 2.3e-35 122.3 15.4 1.1 1 0 0 1 1 1 1 CDK-activating kinase assembly factor MAT1 zf-C3HC4_5 PF17121.5 KFY04317.1 - 7.4e-10 38.6 3.4 1.2e-09 37.9 3.4 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) DUF4483 PF14825.6 KFY04317.1 - 0.0034 17.2 3.1 1.6 8.5 1.8 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF4483) DUF1682 PF07946.14 KFY04317.1 - 0.31 10.2 11.5 0.52 9.5 11.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) DUF4192 PF13830.6 KFY04317.1 - 0.4 10.7 8.6 0.73 9.8 8.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4192) ARGLU PF15346.6 KFY04317.1 - 7.2 6.5 32.1 51 3.7 32.1 2.1 1 1 0 1 1 1 0 Arginine and glutamate-rich 1 Prefoldin_3 PF13758.6 KFY04318.1 - 9.3e-29 99.4 1.2 2.4e-28 98.1 1.2 1.8 1 0 0 1 1 1 1 Prefoldin subunit DUF3835 PF12927.7 KFY04318.1 - 1.4e-24 86.8 13.4 1.6e-24 86.6 0.2 4.5 3 1 1 4 4 4 1 Domain of unknown function (DUF3835) MIS13 PF08202.11 KFY04318.1 - 0.01 15.2 1.5 0.024 14.0 1.5 1.6 1 0 0 1 1 1 0 Mis12-Mtw1 protein family Noelin-1 PF12308.8 KFY04318.1 - 0.043 13.8 1.5 0.15 12.1 0.2 2.5 2 0 0 2 2 2 0 Neurogenesis glycoprotein NPV_P10 PF05531.12 KFY04318.1 - 1 9.9 3.5 19 5.8 0.1 2.7 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein FliJ PF02050.16 KFY04318.1 - 2 8.7 7.9 21 5.3 6.3 2.9 1 1 1 2 2 2 0 Flagellar FliJ protein ANTH PF07651.16 KFY04319.1 - 2e-66 223.8 0.7 2.5e-66 223.5 0.7 1.1 1 0 0 1 1 1 1 ANTH domain ENTH PF01417.20 KFY04319.1 - 8.9e-10 38.7 0.0 1.5e-09 38.0 0.0 1.3 1 0 0 1 1 1 1 ENTH domain Methyltransf_2 PF00891.18 KFY04324.1 - 1.7e-18 66.7 0.0 3.2e-18 65.8 0.0 1.4 1 0 0 1 1 1 1 O-methyltransferase domain Dimerisation2 PF16864.5 KFY04324.1 - 0.0013 18.7 0.0 0.0027 17.7 0.0 1.4 1 0 0 1 1 1 1 Dimerisation domain HTH_IclR PF09339.10 KFY04324.1 - 0.031 14.1 0.0 0.072 12.9 0.0 1.5 1 0 0 1 1 1 0 IclR helix-turn-helix domain PTR2 PF00854.21 KFY04325.1 - 9.7e-71 238.7 0.3 1.7e-70 237.8 0.3 1.4 1 1 0 1 1 1 1 POT family MFS_1 PF07690.16 KFY04325.1 - 9.9e-09 34.6 15.0 7e-08 31.8 16.3 1.9 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KFY04325.1 - 0.41 9.4 19.0 5.9 5.6 3.0 3.5 2 2 1 3 3 3 0 Sugar (and other) transporter MFS_1 PF07690.16 KFY04326.1 - 2.1e-33 115.7 25.2 2.1e-33 115.7 25.2 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily FAA_hydrolase PF01557.18 KFY04327.1 - 4.6e-58 196.5 0.0 5.8e-58 196.1 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family Fungal_trans PF04082.18 KFY04328.1 - 9.2e-15 54.4 0.6 1.7e-14 53.5 0.6 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KFY04328.1 - 1.4e-07 31.5 15.1 2.7e-07 30.6 15.1 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CBM_5_12 PF02839.14 KFY04329.1 - 0.6 10.8 4.4 2.5 8.9 4.4 2.1 1 0 0 1 1 1 0 Carbohydrate binding domain Ank_2 PF12796.7 KFY04332.1 - 4.6e-48 161.7 17.5 4.9e-16 59.1 0.8 7.7 1 1 7 9 9 9 8 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KFY04332.1 - 2.2e-40 136.5 14.9 1.9e-11 44.3 0.2 10.1 7 2 2 10 10 10 8 Ankyrin repeats (many copies) Ank_5 PF13857.6 KFY04332.1 - 1.6e-31 107.9 19.5 2.7e-08 33.9 0.5 10.4 8 4 3 11 11 11 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFY04332.1 - 1.1e-30 102.3 15.8 0.00023 21.4 0.0 13.6 11 2 2 13 13 13 7 Ankyrin repeat Ank PF00023.30 KFY04332.1 - 3.4e-25 87.3 30.5 2.3e-07 30.9 0.2 12.4 10 1 2 12 12 12 7 Ankyrin repeat DUF3447 PF11929.8 KFY04332.1 - 0.17 11.9 0.1 3.4 7.7 0.0 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF3447) HATPase_c PF02518.26 KFY04333.1 - 5.1e-27 94.6 0.0 1.1e-26 93.6 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 KFY04333.1 - 2.5e-22 79.2 0.2 4.8e-22 78.2 0.2 1.5 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.25 KFY04333.1 - 5.4e-17 61.6 0.2 1.2e-16 60.4 0.2 1.7 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PAS_9 PF13426.7 KFY04333.1 - 4.1e-15 55.9 0.0 1.4e-10 41.4 0.0 3.0 3 0 0 3 3 3 2 PAS domain PAS PF00989.25 KFY04333.1 - 1.3e-13 50.9 0.0 3.1e-07 30.4 0.0 2.5 2 0 0 2 2 2 2 PAS fold PAS_4 PF08448.10 KFY04333.1 - 3e-11 43.5 0.0 0.00019 21.6 0.0 2.5 2 0 0 2 2 2 2 PAS fold DER1 PF04511.15 KFY04336.1 - 5.5e-54 183.0 5.9 6.3e-54 182.8 5.9 1.0 1 0 0 1 1 1 1 Der1-like family PNRC PF15365.6 KFY04337.1 - 9.6e-09 34.8 8.7 9.6e-09 34.8 8.7 5.6 5 0 0 5 5 5 2 Proline-rich nuclear receptor coactivator motif zf-rbx1 PF12678.7 KFY04338.1 - 3.7e-25 88.0 13.1 4.9e-25 87.6 13.1 1.2 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 KFY04338.1 - 4.5e-17 61.9 10.0 6e-17 61.5 10.0 1.2 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_2 PF13639.6 KFY04338.1 - 3.1e-06 27.4 14.6 0.0001 22.6 14.6 2.2 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 KFY04338.1 - 8.2e-05 22.4 3.4 8.2e-05 22.4 3.4 2.3 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 KFY04338.1 - 0.0018 18.1 11.8 0.029 14.3 11.8 2.4 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 KFY04338.1 - 0.2 11.5 10.7 0.54 10.2 4.5 2.6 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 KFY04338.1 - 0.53 10.1 16.2 40 4.1 16.2 2.4 1 1 0 1 1 1 0 RING-like zinc finger zf-RING_UBOX PF13445.6 KFY04338.1 - 0.56 10.3 7.7 1.9 8.6 7.7 1.9 1 1 0 1 1 1 0 RING-type zinc-finger FANCL_C PF11793.8 KFY04338.1 - 0.66 10.2 9.3 3.3 8.0 9.5 1.9 1 1 1 2 2 2 0 FANCL C-terminal domain Zn_ribbon_17 PF17120.5 KFY04338.1 - 0.77 9.4 14.9 0.14 11.8 4.7 2.3 1 1 1 2 2 2 0 Zinc-ribbon, C4HC2 type SPC12 PF06645.13 KFY04339.1 - 1.8e-29 101.6 0.5 2.2e-29 101.4 0.5 1.1 1 0 0 1 1 1 1 Microsomal signal peptidase 12 kDa subunit (SPC12) DUF3040 PF11239.8 KFY04339.1 - 0.026 14.8 3.9 0.041 14.1 3.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3040) MerC PF03203.14 KFY04339.1 - 0.033 14.7 0.3 0.033 14.6 0.3 1.1 1 0 0 1 1 1 0 MerC mercury resistance protein DUF3379 PF11859.8 KFY04339.1 - 0.17 11.1 0.3 0.22 10.8 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3379) MS_channel PF00924.18 KFY04339.1 - 0.7 9.4 4.6 1.2 8.6 4.6 1.5 1 1 0 1 1 1 0 Mechanosensitive ion channel CorA PF01544.18 KFY04340.1 - 1.4e-43 149.3 0.2 2.3e-43 148.6 0.2 1.4 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein T6_Ig_like PF18002.1 KFY04340.1 - 0.18 11.7 0.0 0.43 10.5 0.0 1.5 1 0 0 1 1 1 0 T6 antigen Ig like domain zf-Tim10_DDP PF02953.15 KFY04341.1 - 6.3e-24 83.4 1.5 8.4e-24 83.0 1.5 1.2 1 0 0 1 1 1 1 Tim10/DDP family zinc finger DUF228 PF02989.14 KFY04341.1 - 0.074 12.9 0.4 0.089 12.6 0.4 1.1 1 0 0 1 1 1 0 Lyme disease proteins of unknown function YkuI_C PF10388.9 KFY04341.1 - 0.081 12.7 0.2 0.084 12.7 0.2 1.1 1 0 0 1 1 1 0 EAL-domain associated signalling protein domain Ribosomal_L23eN PF03939.13 KFY04342.1 - 5.1e-28 97.0 7.3 1.1e-27 96.0 7.3 1.6 1 0 0 1 1 1 1 Ribosomal protein L23, N-terminal domain Ribosomal_L23 PF00276.20 KFY04342.1 - 2e-15 56.9 1.0 2e-15 56.9 1.0 1.6 2 0 0 2 2 2 1 Ribosomal protein L23 Bmt2 PF11968.8 KFY04343.1 - 3e-87 292.1 0.0 3.6e-87 291.8 0.0 1.1 1 0 0 1 1 1 1 25S rRNA (adenine(2142)-N(1))-methyltransferase, Bmt2 EF-hand_8 PF13833.6 KFY04343.1 - 0.12 12.2 0.1 4 7.4 0.0 3.2 4 0 0 4 4 4 0 EF-hand domain pair Methyltransf_23 PF13489.6 KFY04343.1 - 0.17 11.7 0.0 0.25 11.2 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Aa_trans PF01490.18 KFY04344.1 - 4.3e-62 210.1 25.8 5.2e-62 209.9 25.8 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein eRF1_2 PF03464.15 KFY04345.1 - 4.2e-47 159.8 0.1 7.7e-47 158.9 0.1 1.5 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.15 KFY04345.1 - 1.2e-39 135.2 0.9 2.5e-39 134.2 0.9 1.6 1 0 0 1 1 1 1 eRF1 domain 3 eRF1_1 PF03463.15 KFY04345.1 - 1.2e-21 77.0 0.0 2.1e-21 76.3 0.0 1.4 1 0 0 1 1 1 1 eRF1 domain 1 baeRF_family10 PF18854.1 KFY04345.1 - 2e-10 41.0 0.0 4.1e-10 40.1 0.0 1.5 1 0 0 1 1 1 1 Bacterial archaeo-eukaryotic release factor family 10 acVLRF1 PF18859.1 KFY04345.1 - 1.2e-08 35.3 0.1 1.9e-08 34.7 0.1 1.3 1 0 0 1 1 1 1 Actinobacteria/chloroflexi VLRF1 release factor DUF3440 PF11922.8 KFY04345.1 - 0.14 11.9 0.0 0.3 10.8 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3440) PDT PF00800.18 KFY04346.1 - 2.3e-59 200.3 0.0 6.5e-59 198.8 0.0 1.7 2 0 0 2 2 2 1 Prephenate dehydratase MaoC_dehydratas PF01575.19 KFY04346.1 - 3.1e-05 23.5 0.0 6.5e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 MaoC like domain ACT PF01842.25 KFY04346.1 - 0.032 14.0 0.0 0.08 12.7 0.0 1.7 1 0 0 1 1 1 0 ACT domain Hexokinase_1 PF00349.21 KFY04350.1 - 5.9e-63 212.4 0.0 8.1e-63 211.9 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Hexokinase_2 PF03727.16 KFY04350.1 - 1e-55 188.8 0.0 1.6e-48 165.2 0.0 2.3 2 0 0 2 2 2 2 Hexokinase Zn_clus PF00172.18 KFY04351.1 - 5.9e-06 26.3 8.5 9.9e-06 25.6 8.5 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CAAD PF14159.6 KFY04351.1 - 0.13 12.1 0.0 0.31 10.9 0.0 1.7 1 0 0 1 1 1 0 CAAD domains of cyanobacterial aminoacyl-tRNA synthetase Cutinase PF01083.22 KFY04352.1 - 1.9e-50 171.3 1.4 2.3e-50 171.0 1.4 1.1 1 0 0 1 1 1 1 Cutinase PE-PPE PF08237.11 KFY04352.1 - 0.0013 18.4 0.2 0.002 17.7 0.2 1.3 1 0 0 1 1 1 1 PE-PPE domain DUF2974 PF11187.8 KFY04352.1 - 0.0041 16.7 0.1 0.0066 16.0 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2974) Thioesterase PF00975.20 KFY04352.1 - 0.0048 17.0 0.1 0.0065 16.6 0.1 1.2 1 0 0 1 1 1 1 Thioesterase domain Abhydrolase_1 PF00561.20 KFY04352.1 - 0.0054 16.4 0.1 0.0072 16.0 0.1 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold VirJ PF06057.11 KFY04352.1 - 0.024 14.5 0.0 0.12 12.2 0.0 1.9 1 1 1 2 2 2 0 Bacterial virulence protein (VirJ) Lipase_3 PF01764.25 KFY04352.1 - 0.051 13.4 0.0 0.073 12.9 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) Palm_thioest PF02089.15 KFY04352.1 - 0.06 13.2 0.0 0.061 13.2 0.0 1.1 1 0 0 1 1 1 0 Palmitoyl protein thioesterase MFS_1 PF07690.16 KFY04353.1 - 3.6e-35 121.5 34.1 5.5e-35 120.9 34.1 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily COesterase PF00135.28 KFY04354.1 - 5.5e-72 243.3 0.0 7.6e-72 242.8 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KFY04354.1 - 3.2e-08 33.7 0.5 4.1e-05 23.5 0.0 2.3 2 0 0 2 2 2 2 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 KFY04354.1 - 0.0038 16.1 0.0 1.3 7.8 0.0 2.1 2 0 0 2 2 2 2 Steryl acetyl hydrolase Fungal_trans PF04082.18 KFY04355.1 - 0.00031 19.9 0.6 0.00064 18.8 0.6 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KFY04357.1 - 0.012 15.7 13.1 0.012 15.7 13.1 2.2 2 0 0 2 2 2 0 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF4083 PF13314.6 KFY04357.1 - 0.094 12.7 1.6 0.21 11.6 0.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4083) AP_endonuc_2 PF01261.24 KFY04358.1 - 1.8e-28 99.4 0.0 2.4e-28 99.0 0.0 1.1 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel ADP_ribosyl_GH PF03747.14 KFY04359.1 - 1.1e-45 156.6 0.1 2.4e-30 106.3 0.0 2.7 2 1 1 3 3 3 2 ADP-ribosylglycohydrolase Glyco_hydro_43 PF04616.14 KFY04359.1 - 7.8e-27 94.3 6.8 1.3e-26 93.6 6.8 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 GH43_C2 PF17851.1 KFY04359.1 - 3e-19 69.5 0.0 5.1e-19 68.8 0.0 1.3 1 0 0 1 1 1 1 Beta xylosidase C-terminal Concanavalin A-like domain Rick_17kDa_Anti PF05433.15 KFY04359.1 - 0.011 15.5 8.3 0.62 10.0 0.6 2.5 2 0 0 2 2 2 0 Glycine zipper 2TM domain Gly-zipper_Omp PF13488.6 KFY04359.1 - 0.078 13.0 6.7 0.91 9.6 1.0 2.5 2 0 0 2 2 2 0 Glycine zipper Gly-zipper_YMGG PF13441.6 KFY04359.1 - 0.18 11.6 7.1 0.85 9.4 1.6 2.4 2 0 0 2 2 2 0 YMGG-like Gly-zipper Gly-zipper_OmpA PF13436.6 KFY04359.1 - 2.5 8.0 6.5 2.7 7.9 1.2 2.5 2 0 0 2 2 2 0 Glycine-zipper domain Ribosomal_L7Ae PF01248.26 KFY04360.1 - 1.5e-22 79.1 0.0 1.7e-22 79.0 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Dynamin_N PF00350.23 KFY04361.1 - 6e-31 107.8 0.0 1.6e-30 106.4 0.0 1.8 1 0 0 1 1 1 1 Dynamin family Dynamin_M PF01031.20 KFY04361.1 - 5.4e-27 94.7 0.1 2.6e-25 89.2 0.1 2.3 2 0 0 2 2 2 1 Dynamin central region GED PF02212.18 KFY04361.1 - 0.0014 18.7 0.1 0.0044 17.2 0.1 1.9 1 1 0 1 1 1 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.23 KFY04361.1 - 0.003 17.6 0.2 0.051 13.6 0.2 2.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.6 KFY04361.1 - 0.038 14.4 0.1 0.2 12.0 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain AAA_29 PF13555.6 KFY04361.1 - 0.1 12.3 0.0 0.29 10.9 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain Zn_clus PF00172.18 KFY04362.1 - 4.6e-06 26.7 11.8 1.6e-05 24.9 11.8 2.0 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain NmrA PF05368.13 KFY04363.1 - 1.4e-54 185.2 0.0 2.1e-54 184.6 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KFY04363.1 - 6.4e-11 42.5 0.0 1.3e-10 41.5 0.0 1.5 1 0 0 1 1 1 1 NAD(P)H-binding Sacchrp_dh_NADP PF03435.18 KFY04363.1 - 9.3e-05 22.7 0.0 0.0006 20.1 0.0 2.2 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain 3Beta_HSD PF01073.19 KFY04363.1 - 0.0067 15.5 0.0 0.01 14.8 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family TrkA_N PF02254.18 KFY04363.1 - 0.014 15.7 0.1 0.026 14.8 0.1 1.5 1 0 0 1 1 1 0 TrkA-N domain VPS9 PF02204.18 KFY04368.1 - 1.1e-29 102.7 0.1 2e-29 101.9 0.1 1.3 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain DUF5601 PF18151.1 KFY04368.1 - 1.9e-15 56.9 0.1 4.1e-15 55.8 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF5601) CUE PF02845.16 KFY04368.1 - 1.7e-10 40.4 0.0 3.2e-10 39.5 0.0 1.5 1 0 0 1 1 1 1 CUE domain HEAT_EZ PF13513.6 KFY04372.1 - 7.5e-18 64.6 3.7 3.6e-09 36.9 0.1 8.0 6 2 3 9 9 8 4 HEAT-like repeat HEAT_2 PF13646.6 KFY04372.1 - 3.6e-16 59.3 5.4 0.00025 21.4 0.1 6.7 4 1 3 7 7 7 3 HEAT repeats HEAT PF02985.22 KFY04372.1 - 1e-14 53.3 7.3 2.6e-05 24.1 0.0 9.1 10 0 0 10 10 8 1 HEAT repeat Vac14_Fab1_bd PF12755.7 KFY04372.1 - 8.8e-08 32.7 0.6 0.17 12.5 0.0 5.2 5 2 0 5 5 5 2 Vacuolar 14 Fab1-binding region Cnd1 PF12717.7 KFY04372.1 - 1.2e-05 25.4 3.9 0.023 14.7 0.3 4.7 3 2 1 4 4 4 1 non-SMC mitotic condensation complex subunit 1 IBN_N PF03810.19 KFY04372.1 - 5.6e-05 23.0 3.9 0.00063 19.6 0.3 3.6 3 0 0 3 3 3 1 Importin-beta N-terminal domain UME PF08064.13 KFY04372.1 - 8.2e-05 22.5 0.0 0.68 9.9 0.0 4.2 3 1 0 3 3 3 1 UME (NUC010) domain MMS19_C PF12460.8 KFY04372.1 - 9.5e-05 21.7 3.3 0.00018 20.8 0.6 2.9 4 0 0 4 4 4 1 RNAPII transcription regulator C-terminal Adaptin_N PF01602.20 KFY04372.1 - 0.00011 20.9 0.3 0.0019 16.9 0.0 2.8 3 1 0 3 3 3 1 Adaptin N terminal region RTP1_C1 PF10363.9 KFY04372.1 - 0.00011 22.3 0.2 0.044 14.0 0.0 4.4 5 1 1 6 6 4 1 Required for nuclear transport of RNA pol II C-terminus 1 Neurochondrin PF05536.11 KFY04372.1 - 0.00021 19.8 0.5 0.00061 18.3 0.5 1.8 1 0 0 1 1 1 1 Neurochondrin Arm PF00514.23 KFY04372.1 - 0.00065 19.7 0.6 8.9 6.5 0.0 5.1 6 0 0 6 6 5 1 Armadillo/beta-catenin-like repeat IFRD PF05004.13 KFY04372.1 - 0.0011 18.1 3.9 0.22 10.6 0.1 3.6 1 1 2 3 3 3 1 Interferon-related developmental regulator (IFRD) MMS19_N PF14500.6 KFY04372.1 - 0.0013 18.4 1.1 0.079 12.5 0.0 2.6 2 0 0 2 2 2 1 Dos2-interacting transcription regulator of RNA-Pol-II Tti2 PF10521.9 KFY04372.1 - 0.0016 18.0 0.2 0.016 14.7 0.0 2.8 2 1 1 3 3 3 1 Tti2 family ParcG PF10274.9 KFY04372.1 - 0.0062 16.7 0.3 0.076 13.1 0.1 2.7 2 1 1 3 3 3 1 Parkin co-regulated protein Dopey_N PF04118.14 KFY04372.1 - 0.029 13.5 0.9 5 6.1 0.0 3.3 3 0 0 3 3 3 0 Dopey, N-terminal RIX1 PF08167.12 KFY04372.1 - 0.047 13.4 0.0 1.2 8.9 0.0 3.2 3 0 0 3 3 3 0 rRNA processing/ribosome biogenesis DUF3385 PF11865.8 KFY04372.1 - 0.049 13.5 2.8 90 2.9 0.0 5.8 4 2 0 4 4 4 0 Domain of unknown function (DUF3385) DUF4211 PF13926.6 KFY04372.1 - 0.11 12.6 0.1 0.35 10.9 0.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4211) Acetyltransf_1 PF00583.25 KFY04373.1 - 6.5e-09 36.1 0.0 7.9e-09 35.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KFY04373.1 - 7e-07 29.6 0.0 1.2e-06 28.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 KFY04373.1 - 1.6e-06 28.1 0.0 3.5e-06 27.0 0.0 1.5 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KFY04373.1 - 0.00044 20.2 0.0 0.00075 19.4 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein FtsJ PF01728.19 KFY04374.1 - 8.9e-64 214.8 0.0 1.6e-63 214.0 0.0 1.4 1 1 0 1 1 1 1 FtsJ-like methyltransferase DEAD PF00270.29 KFY04375.1 - 2.2e-43 148.1 0.1 3.8e-43 147.3 0.1 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KFY04375.1 - 1.2e-26 93.2 0.0 2.1e-25 89.2 0.0 2.6 3 0 0 3 3 3 1 Helicase conserved C-terminal domain SET PF00856.28 KFY04375.1 - 0.054 13.9 1.9 0.13 12.7 1.9 1.6 1 0 0 1 1 1 0 SET domain AAA_22 PF13401.6 KFY04375.1 - 0.12 12.7 0.2 0.35 11.1 0.2 1.9 1 1 0 1 1 1 0 AAA domain RR_TM4-6 PF06459.12 KFY04375.1 - 0.64 9.8 13.3 1.4 8.7 13.3 1.5 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 CDC27 PF09507.10 KFY04375.1 - 0.83 9.0 25.5 1.9 7.8 25.5 1.5 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Raftlin PF15250.6 KFY04375.1 - 1.5 7.5 8.4 2.3 6.9 8.4 1.2 1 0 0 1 1 1 0 Raftlin UCH PF00443.29 KFY04376.1 - 6.7e-38 130.6 0.0 1.1e-37 129.9 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 KFY04376.1 - 8.9e-15 55.1 0.1 1.4e-10 41.3 0.0 2.2 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase Rhodanese PF00581.20 KFY04376.1 - 7.1e-05 23.3 0.0 0.00019 21.9 0.0 1.8 1 0 0 1 1 1 1 Rhodanese-like domain SET PF00856.28 KFY04376.1 - 0.11 12.9 0.2 31 4.9 0.0 2.9 3 0 0 3 3 3 0 SET domain Vps16_N PF04841.13 KFY04377.1 - 8e-99 331.2 0.0 1.1e-98 330.7 0.0 1.2 1 0 0 1 1 1 1 Vps16, N-terminal region Vps16_C PF04840.12 KFY04377.1 - 5.8e-86 288.4 0.0 9.2e-86 287.8 0.0 1.3 1 0 0 1 1 1 1 Vps16, C-terminal region Coatomer_WDAD PF04053.14 KFY04377.1 - 0.0031 16.6 0.0 2.1 7.3 0.0 3.2 3 0 0 3 3 3 2 Coatomer WD associated region ANAPC4_WD40 PF12894.7 KFY04377.1 - 0.032 14.5 0.0 0.26 11.6 0.0 2.4 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain FHA PF00498.26 KFY04378.1 - 7.2e-14 51.9 0.0 1.3e-13 51.1 0.0 1.4 1 0 0 1 1 1 1 FHA domain zf-RING_11 PF17123.5 KFY04378.1 - 7.3e-13 48.0 3.7 1.5e-12 47.0 3.7 1.6 1 0 0 1 1 1 1 RING-like zinc finger zf-RING_2 PF13639.6 KFY04378.1 - 2.9e-05 24.3 10.3 5.9e-05 23.3 10.3 1.6 1 0 0 1 1 1 1 Ring finger domain MARVEL PF01284.23 KFY04378.1 - 0.0024 17.9 8.2 0.0043 17.1 8.2 1.4 1 0 0 1 1 1 1 Membrane-associating domain Yop-YscD_cpl PF16697.5 KFY04378.1 - 0.0036 17.6 0.0 0.0073 16.6 0.0 1.4 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain zf-C3HC4 PF00097.25 KFY04378.1 - 0.0052 16.6 8.0 0.0096 15.8 8.0 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) NCE101 PF11654.8 KFY04378.1 - 0.0094 15.6 0.6 3.4 7.5 0.0 2.5 2 0 0 2 2 2 2 Non-classical export protein 1 zf-RING_5 PF14634.6 KFY04378.1 - 0.11 12.5 6.6 0.19 11.7 6.6 1.5 1 0 0 1 1 1 0 zinc-RING finger domain zf-C3HC4_2 PF13923.6 KFY04378.1 - 0.47 10.3 8.7 0.95 9.4 8.7 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) PHD PF00628.29 KFY04378.1 - 0.48 10.4 6.3 0.97 9.4 6.3 1.5 1 0 0 1 1 1 0 PHD-finger zf-rbx1 PF12678.7 KFY04378.1 - 0.94 9.8 7.8 2.1 8.7 7.8 1.6 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 KFY04378.1 - 1.2 9.2 8.7 2.6 8.1 8.7 1.6 1 0 0 1 1 1 0 RING-type zinc-finger OrfB_Zn_ribbon PF07282.11 KFY04378.1 - 1.9 8.5 5.1 32 4.5 1.4 2.5 1 1 1 2 2 2 0 Putative transposase DNA-binding domain Peptidase_M16_C PF05193.21 KFY04379.1 - 3.1e-53 180.5 0.0 6.2e-53 179.5 0.0 1.5 1 0 0 1 1 1 1 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 KFY04379.1 - 1.9e-43 148.0 0.0 4.7e-42 143.5 0.0 2.1 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) QSregVF PF13652.6 KFY04383.1 - 0.099 12.7 0.1 0.099 12.7 0.1 1.1 1 0 0 1 1 1 0 Putative quorum-sensing-regulated virulence factor Acyl_transf_3 PF01757.22 KFY04384.1 - 4.4e-09 35.9 26.8 1.1e-08 34.5 26.7 1.7 1 1 0 1 1 1 1 Acyltransferase family Caps_synth_CapC PF14102.6 KFY04384.1 - 0.46 10.9 0.1 0.46 10.9 0.1 2.7 3 0 0 3 3 3 0 Capsule biosynthesis CapC APG17 PF04108.12 KFY04387.1 - 9.8e-123 410.2 0.0 1.2e-122 409.9 0.0 1.0 1 0 0 1 1 1 1 Autophagy protein Apg17 Yuri_gagarin PF15934.5 KFY04387.1 - 0.00084 19.3 0.1 0.024 14.5 0.0 2.3 2 0 0 2 2 2 1 Yuri gagarin DUF4795 PF16043.5 KFY04387.1 - 0.0037 16.9 0.1 2.7 7.6 0.0 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF4795) SesA PF17107.5 KFY04387.1 - 0.045 13.9 2.4 4.9 7.4 0.1 3.4 2 2 1 3 3 3 0 N-terminal domain on NACHT_NTPase and P-loop NTPases Focal_AT PF03623.13 KFY04387.1 - 0.097 12.7 1.0 0.39 10.7 0.0 2.4 3 0 0 3 3 3 0 Focal adhesion targeting region DUF1664 PF07889.12 KFY04387.1 - 0.34 10.9 1.0 5.6 7.0 0.0 2.9 3 1 0 3 3 3 0 Protein of unknown function (DUF1664) AIP3 PF03915.13 KFY04387.1 - 0.49 9.4 2.8 3.9 6.5 0.7 2.6 2 1 0 2 2 2 0 Actin interacting protein 3 Pox_MCEL PF03291.16 KFY04402.1 - 8e-28 97.5 0.0 5.2e-20 71.8 0.0 2.4 2 1 0 2 2 2 2 mRNA capping enzyme zf-Nse PF11789.8 KFY04403.1 - 5e-15 55.0 0.0 1.1e-14 53.9 0.0 1.6 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_UBOX PF13445.6 KFY04403.1 - 0.0094 16.0 0.0 0.018 15.1 0.0 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-MIZ PF02891.20 KFY04403.1 - 0.15 11.8 0.0 0.31 10.8 0.0 1.5 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger MFS_1 PF07690.16 KFY04405.1 - 3.6e-42 144.6 31.0 3.6e-42 144.6 31.0 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 KFY04405.1 - 8.9e-08 31.0 4.7 1.4e-07 30.4 4.7 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) TF_Otx PF03529.13 KFY04405.1 - 0.17 12.3 0.0 0.4 11.1 0.0 1.6 1 0 0 1 1 1 0 Otx1 transcription factor DUF3817 PF12823.7 KFY04405.1 - 0.99 10.3 8.5 6.5 7.6 5.0 3.3 2 1 0 2 2 2 0 Domain of unknown function (DUF3817) MAPEG PF01124.18 KFY04406.1 - 7e-16 58.3 2.9 1e-15 57.8 2.9 1.1 1 0 0 1 1 1 1 MAPEG family ABC2_membrane PF01061.24 KFY04407.1 - 1.5e-84 282.6 54.1 3.5e-47 160.5 18.7 3.7 4 0 0 4 4 4 2 ABC-2 type transporter ABC_tran PF00005.27 KFY04407.1 - 1.1e-34 119.9 0.0 3.1e-17 63.4 0.0 2.4 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.12 KFY04407.1 - 1.8e-33 114.3 1.4 2.1e-27 94.9 0.0 3.1 2 0 0 2 2 2 2 CDR ABC transporter ABC_trans_N PF14510.6 KFY04407.1 - 9.2e-11 42.2 0.1 3.2e-10 40.5 0.0 2.0 2 0 0 2 2 1 1 ABC-transporter N-terminal ABC2_membrane_3 PF12698.7 KFY04407.1 - 5e-10 39.0 38.4 4.6e-05 22.7 13.5 2.3 2 0 0 2 2 2 2 ABC-2 family transporter protein AAA_16 PF13191.6 KFY04407.1 - 1.4e-05 25.5 0.1 0.0013 19.2 0.1 2.6 2 0 0 2 2 2 1 AAA ATPase domain RsgA_GTPase PF03193.16 KFY04407.1 - 2.9e-05 24.0 0.4 0.00035 20.5 0.0 2.5 3 0 0 3 3 3 1 RsgA GTPase AAA_21 PF13304.6 KFY04407.1 - 3.3e-05 23.9 0.0 0.12 12.2 0.0 2.5 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_18 PF13238.6 KFY04407.1 - 0.00012 22.7 0.0 0.076 13.6 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.6 KFY04407.1 - 0.00013 21.6 0.1 0.0094 15.5 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 KFY04407.1 - 0.00032 20.4 0.7 0.14 11.9 0.1 2.9 3 0 0 3 3 3 1 P-loop containing region of AAA domain AAA_22 PF13401.6 KFY04407.1 - 0.0017 18.6 0.6 0.078 13.3 0.2 3.0 2 1 0 2 2 2 1 AAA domain AAA_33 PF13671.6 KFY04407.1 - 0.0034 17.6 1.9 0.078 13.1 0.0 3.1 3 0 0 3 3 3 1 AAA domain MMR_HSR1 PF01926.23 KFY04407.1 - 0.0035 17.4 0.4 0.35 11.0 0.1 2.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase cobW PF02492.19 KFY04407.1 - 0.01 15.4 0.3 0.042 13.4 0.0 2.0 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_28 PF13521.6 KFY04407.1 - 0.016 15.4 0.3 0.016 15.4 0.3 2.5 3 0 0 3 3 2 0 AAA domain FtsK_SpoIIIE PF01580.18 KFY04407.1 - 0.036 13.4 0.4 7.3 5.9 0.1 2.4 2 0 0 2 2 2 0 FtsK/SpoIIIE family NACHT PF05729.12 KFY04407.1 - 0.04 13.8 0.8 0.56 10.1 0.1 2.4 2 0 0 2 2 2 0 NACHT domain SMC_N PF02463.19 KFY04407.1 - 0.062 12.7 0.1 1.4 8.3 0.0 2.7 3 0 0 3 3 3 0 RecF/RecN/SMC N terminal domain AAA_30 PF13604.6 KFY04407.1 - 0.064 13.0 0.5 1.8 8.3 0.2 2.5 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.6 KFY04407.1 - 0.081 13.4 0.3 3.1 8.2 0.1 2.7 2 0 0 2 2 2 0 AAA domain DUF373 PF04123.13 KFY04407.1 - 3.8 6.9 7.5 8 5.8 7.5 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF373) HVSL PF09749.9 KFY04408.1 - 0.22 10.9 0.0 0.37 10.2 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised conserved protein DFRP_C PF16543.5 KFY04414.1 - 3.6e-26 91.5 7.4 3.6e-26 91.5 7.4 3.4 3 1 0 3 3 3 1 DRG Family Regulatory Proteins, Tma46 Torus PF16131.5 KFY04414.1 - 3.3e-06 27.8 18.3 0.00035 21.2 5.4 3.8 2 1 1 3 3 3 2 Torus domain zf-CCCH PF00642.24 KFY04414.1 - 4.6e-06 26.4 3.5 4.6e-06 26.4 3.5 2.6 3 0 0 3 3 3 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 KFY04414.1 - 2.7e-05 23.9 11.9 0.0011 18.7 3.8 3.1 3 0 0 3 3 3 2 CCCH-type zinc finger zf_CCCH_4 PF18345.1 KFY04414.1 - 3.6e-05 23.7 21.2 0.00089 19.2 9.9 3.1 3 0 0 3 3 3 2 Zinc finger domain zf-CCCH_2 PF14608.6 KFY04414.1 - 0.013 16.0 16.4 0.25 11.9 5.5 2.9 2 1 0 2 2 2 0 RNA-binding, Nab2-type zinc finger zf-CCCH_3 PF15663.5 KFY04414.1 - 0.63 10.3 8.3 0.74 10.0 2.9 2.6 1 1 0 2 2 2 0 Zinc-finger containing family RRM_1 PF00076.22 KFY04415.1 - 2e-16 59.5 0.0 3.7e-16 58.7 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FoP_duplication PF13865.6 KFY04415.1 - 5.7e-06 26.8 0.6 5.7e-06 26.8 0.6 3.3 2 1 1 3 3 3 1 C-terminal duplication domain of Friend of PRMT1 RRM_occluded PF16842.5 KFY04415.1 - 0.0074 16.1 0.0 0.013 15.3 0.0 1.4 1 0 0 1 1 1 1 Occluded RNA-recognition motif CCER1 PF15482.6 KFY04415.1 - 0.037 13.9 2.0 1.5 8.6 0.3 2.2 2 0 0 2 2 2 0 Coiled-coil domain-containing glutamate-rich protein family 1 Sortilin-Vps10 PF15902.5 KFY04416.1 - 5.2e-15 55.2 8.8 0.00018 20.5 0.3 5.7 4 2 1 6 6 6 5 Sortilin, neurotensin receptor 3, BNR PF02012.20 KFY04416.1 - 1.2e-12 45.9 19.6 0.29 11.3 0.0 9.2 8 0 0 8 8 8 5 BNR/Asp-box repeat CBM_1 PF00734.18 KFY04416.1 - 1.1e-09 38.0 11.0 1.1e-09 38.0 11.0 2.1 2 0 0 2 2 2 1 Fungal cellulose binding domain BNR_6 PF15899.5 KFY04416.1 - 0.00042 20.1 5.5 8.5 6.8 0.0 6.5 7 0 0 7 7 7 1 BNR-Asp box repeat PSII_BNR PF14870.6 KFY04416.1 - 0.0061 15.9 16.0 1.7 7.8 0.1 6.1 5 2 1 6 6 6 3 Photosynthesis system II assembly factor YCF48 Pollen_allerg_1 PF01357.21 KFY04416.1 - 0.04 13.9 0.7 6 7.0 0.0 3.8 3 1 1 4 4 4 0 Pollen allergen DUF2452 PF10504.9 KFY04416.1 - 0.2 11.1 0.0 0.37 10.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2452) Fungal_trans PF04082.18 KFY04417.1 - 2.2e-32 112.2 0.1 5.6e-32 110.8 0.0 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KFY04417.1 - 1.5e-08 34.6 15.2 2.5e-08 33.9 15.2 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ribosomal_L26 PF16906.5 KFY04418.1 - 4e-38 129.8 3.3 5.4e-38 129.3 3.3 1.2 1 0 0 1 1 1 1 Ribosomal proteins L26 eukaryotic, L24P archaeal KOW PF00467.29 KFY04418.1 - 1.6e-08 34.2 0.5 3.7e-08 33.0 0.5 1.7 1 0 0 1 1 1 1 KOW motif DUF1223 PF06764.11 KFY04418.1 - 0.1 12.6 0.0 0.12 12.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1223) adh_short PF00106.25 KFY04419.1 - 1.7e-22 79.9 0.1 2.4e-22 79.3 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KFY04419.1 - 7e-19 68.3 0.0 1.1e-18 67.7 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KFY04419.1 - 4.2e-05 23.5 0.0 0.00033 20.6 0.0 1.9 2 0 0 2 2 2 1 KR domain PGM_PMM_III PF02880.16 KFY04419.1 - 0.14 12.3 0.0 0.22 11.7 0.0 1.3 1 0 0 1 1 1 0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III OmpH PF03938.14 KFY04420.1 - 0.00069 20.0 1.3 0.00069 20.0 1.3 1.9 2 0 0 2 2 2 1 Outer membrane protein (OmpH-like) DUF4559 PF15112.6 KFY04420.1 - 0.0023 17.7 1.4 0.0045 16.7 1.4 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4559) DUF883 PF05957.13 KFY04420.1 - 0.0032 18.0 1.5 0.0032 18.0 1.5 1.8 2 0 0 2 2 2 1 Bacterial protein of unknown function (DUF883) Tup_N PF08581.10 KFY04420.1 - 0.14 12.5 0.3 0.14 12.5 0.3 2.8 1 1 1 3 3 3 0 Tup N-terminal XhlA PF10779.9 KFY04420.1 - 0.37 11.0 3.7 7.4 6.9 0.3 2.6 2 0 0 2 2 2 0 Haemolysin XhlA TPR_MLP1_2 PF07926.12 KFY04420.1 - 0.42 10.7 10.6 0.72 9.9 3.9 2.6 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein Lipase_chap PF03280.14 KFY04423.1 - 0.011 15.6 3.1 0.011 15.6 3.1 2.6 4 0 0 4 4 4 0 Proteobacterial lipase chaperone protein TRAPPC10 PF12584.8 KFY04428.1 - 2e-27 95.8 0.0 1e-26 93.5 0.0 2.1 2 0 0 2 2 2 1 Trafficking protein particle complex subunit 10, TRAPPC10 Methyltransf_23 PF13489.6 KFY04428.1 - 1.4e-19 70.5 0.0 3e-19 69.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KFY04428.1 - 2.5e-09 37.7 0.0 1.1e-08 35.7 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 KFY04428.1 - 2.4e-07 31.3 0.0 7.3e-07 29.8 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KFY04428.1 - 1.3e-05 25.1 0.0 4e-05 23.5 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KFY04428.1 - 0.00015 22.5 0.0 0.0012 19.6 0.0 2.6 2 1 0 2 2 2 1 Methyltransferase domain Foie-gras_1 PF11817.8 KFY04428.1 - 0.00044 19.9 0.2 0.00084 19.0 0.2 1.4 1 0 0 1 1 1 1 Foie gras liver health family 1 MTS PF05175.14 KFY04428.1 - 0.0065 16.0 0.0 0.015 14.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain FtsJ PF01728.19 KFY04428.1 - 0.079 13.1 0.0 0.22 11.6 0.0 1.7 1 0 0 1 1 1 0 FtsJ-like methyltransferase Methyltransf_4 PF02390.17 KFY04428.1 - 0.13 11.7 0.0 0.51 9.8 0.0 2.0 2 0 0 2 2 2 0 Putative methyltransferase HlyIII PF03006.20 KFY04429.1 - 1.9e-60 204.4 15.9 2.4e-60 204.1 15.9 1.1 1 0 0 1 1 1 1 Haemolysin-III related FmiP_Thoc5 PF09766.9 KFY04430.1 - 7.5e-32 111.0 5.2 1e-31 110.5 5.2 1.2 1 0 0 1 1 1 1 Fms-interacting protein/Thoc5 APG6_N PF17675.1 KFY04430.1 - 0.093 13.3 10.9 1.2 9.6 2.1 2.3 2 0 0 2 2 2 0 Apg6 coiled-coil region K-box PF01486.17 KFY04430.1 - 0.11 12.7 0.3 0.11 12.7 0.3 2.8 2 1 1 3 3 3 0 K-box region IMD PF08397.11 KFY04430.1 - 0.32 10.3 4.0 0.25 10.7 0.1 2.1 2 0 0 2 2 2 0 IRSp53/MIM homology domain Mod_r PF07200.13 KFY04430.1 - 0.42 10.7 8.9 0.4 10.8 1.8 2.3 2 0 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein Phage_tail_APC PF16778.5 KFY04430.1 - 0.5 10.3 2.6 0.73 9.8 0.1 2.5 3 0 0 3 3 3 0 Phage tail assembly chaperone protein Casc1_N PF15927.5 KFY04430.1 - 0.52 10.0 11.3 0.19 11.4 7.1 2.0 2 0 0 2 2 2 0 Cancer susceptibility candidate 1 N-terminus RasGAP_C PF03836.15 KFY04430.1 - 0.93 9.6 5.9 0.23 11.6 0.3 2.2 2 0 0 2 2 2 0 RasGAP C-terminus Spc7 PF08317.11 KFY04430.1 - 1.1 8.1 7.8 1.9 7.3 1.1 2.2 2 0 0 2 2 2 0 Spc7 kinetochore protein Ubie_methyltran PF01209.18 KFY04433.1 - 2.6e-59 200.4 0.0 3.1e-59 200.1 0.0 1.0 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_11 PF08241.12 KFY04433.1 - 1e-16 61.4 0.0 2.7e-16 60.0 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 KFY04433.1 - 6.2e-15 55.7 0.0 1.3e-14 54.7 0.0 1.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 KFY04433.1 - 1.2e-09 38.2 0.0 1.3e-09 38.0 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KFY04433.1 - 3.5e-08 34.1 0.0 4.8e-08 33.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KFY04433.1 - 5.3e-06 26.4 0.0 7.1e-06 26.0 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.15 KFY04433.1 - 0.00055 19.8 0.0 0.00073 19.4 0.0 1.2 1 0 0 1 1 1 1 Hypothetical methyltransferase DUF2433 PF10360.9 KFY04434.1 - 1.3e-49 167.4 0.0 2.2e-49 166.7 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2433) Metallophos_2 PF12850.7 KFY04434.1 - 0.00044 20.5 0.0 0.005 17.1 0.0 2.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.28 KFY04434.1 - 0.0025 18.4 0.0 0.0069 16.9 0.0 1.8 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase TFIIA PF03153.13 KFY04434.1 - 0.85 9.5 10.0 1.3 8.9 10.0 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit EF_assoc_2 PF08356.12 KFY04435.1 - 2.2e-35 120.5 0.0 4.3e-35 119.6 0.0 1.5 1 0 0 1 1 1 1 EF hand associated EF_assoc_1 PF08355.12 KFY04435.1 - 8.5e-31 105.4 0.3 1.6e-30 104.5 0.3 1.5 1 0 0 1 1 1 1 EF hand associated Ras PF00071.22 KFY04435.1 - 7.9e-26 90.6 0.0 1e-15 57.7 0.0 2.2 2 0 0 2 2 2 2 Ras family Roc PF08477.13 KFY04435.1 - 1.3e-13 51.2 0.0 1.3e-08 35.1 0.0 2.4 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 KFY04435.1 - 1.3e-09 38.1 0.0 3.7e-05 23.8 0.0 2.9 2 1 0 2 2 2 2 50S ribosome-binding GTPase EF-hand_1 PF00036.32 KFY04435.1 - 9e-09 34.3 1.5 0.0034 16.8 0.5 2.7 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 KFY04435.1 - 7e-07 28.7 1.7 0.022 14.6 0.2 2.7 2 0 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.6 KFY04435.1 - 9e-07 29.3 0.5 0.00061 20.2 0.1 2.6 2 0 0 2 2 2 1 EF-hand domain pair Dynamin_N PF00350.23 KFY04435.1 - 9e-06 25.8 1.5 0.18 11.9 0.0 3.6 3 1 1 4 4 3 2 Dynamin family AAA_16 PF13191.6 KFY04435.1 - 4.8e-05 23.8 0.0 0.17 12.2 0.0 2.7 2 0 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.6 KFY04435.1 - 0.00016 21.3 0.0 0.13 12.0 0.0 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain EF-hand_5 PF13202.6 KFY04435.1 - 0.00026 20.3 3.3 0.07 12.7 1.7 2.7 2 0 0 2 2 2 1 EF hand AAA_28 PF13521.6 KFY04435.1 - 0.00066 20.0 0.0 0.63 10.3 0.0 2.6 2 0 0 2 2 2 1 AAA domain EF-hand_8 PF13833.6 KFY04435.1 - 0.0011 18.8 2.1 1.1 9.2 0.0 2.8 2 0 0 2 2 2 2 EF-hand domain pair AAA_22 PF13401.6 KFY04435.1 - 0.0023 18.2 0.0 0.64 10.3 0.0 2.5 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 KFY04435.1 - 0.0045 17.4 0.0 0.19 12.2 0.0 2.6 2 0 0 2 2 2 1 RNA helicase AAA_24 PF13479.6 KFY04435.1 - 0.014 15.1 0.1 0.32 10.7 0.0 2.6 3 0 0 3 3 3 0 AAA domain Ploopntkinase3 PF18751.1 KFY04435.1 - 0.02 14.8 0.0 1.6 8.6 0.0 2.3 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 GTP_EFTU PF00009.27 KFY04435.1 - 0.021 14.4 0.0 13 5.3 0.0 3.1 3 0 0 3 3 3 0 Elongation factor Tu GTP binding domain EF-hand_10 PF14788.6 KFY04435.1 - 0.021 14.7 0.2 0.1 12.5 0.0 2.0 2 0 0 2 2 2 0 EF hand RsgA_GTPase PF03193.16 KFY04435.1 - 0.025 14.5 0.1 1.2 9.0 0.0 3.0 3 0 0 3 3 3 0 RsgA GTPase AAA_18 PF13238.6 KFY04435.1 - 0.041 14.4 0.1 1.2 9.6 0.0 2.9 2 1 0 2 2 2 0 AAA domain AAA_25 PF13481.6 KFY04435.1 - 0.1 12.1 0.1 11 5.5 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 KFY04435.1 - 0.12 12.6 0.0 21 5.3 0.0 2.7 2 1 0 2 2 2 0 AAA domain ABC_tran PF00005.27 KFY04435.1 - 0.12 12.8 0.0 7 7.2 0.0 2.4 2 0 0 2 2 2 0 ABC transporter PriCT_1 PF08708.11 KFY04435.1 - 0.13 12.0 0.0 0.45 10.3 0.0 1.9 2 0 0 2 2 2 0 Primase C terminal 1 (PriCT-1) FtsK_SpoIIIE PF01580.18 KFY04435.1 - 0.14 11.5 0.1 12 5.1 0.0 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family DUF815 PF05673.13 KFY04435.1 - 0.14 11.3 0.0 1.5 7.9 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF815) WD40 PF00400.32 KFY04437.1 - 1.6e-13 50.8 12.5 6.3e-05 23.7 0.2 5.2 5 1 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFY04437.1 - 4.2e-10 39.8 0.1 0.00034 20.9 0.0 3.5 1 1 2 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KFY04437.1 - 8.2e-05 22.6 0.0 0.0014 18.6 0.0 2.2 1 1 1 2 2 2 1 Eukaryotic translation initiation factor eIF2A IKI3 PF04762.12 KFY04437.1 - 0.00024 19.3 0.0 0.00032 18.9 0.0 1.1 1 0 0 1 1 1 1 IKI3 family Cytochrom_D1 PF02239.16 KFY04437.1 - 0.0041 15.7 0.0 0.027 13.0 0.0 2.1 1 1 0 1 1 1 1 Cytochrome D1 heme domain PD40 PF07676.12 KFY04437.1 - 0.007 16.3 0.0 2.6 8.1 0.0 2.6 2 0 0 2 2 2 2 WD40-like Beta Propeller Repeat VID27 PF08553.10 KFY04437.1 - 0.19 10.8 0.0 0.27 10.2 0.0 1.2 1 0 0 1 1 1 0 VID27 C-terminal WD40-like domain EGF_2 PF07974.13 KFY04441.1 - 6.8e-05 23.1 5.6 0.00029 21.1 5.6 2.0 1 1 0 1 1 1 1 EGF-like domain I-EGF_1 PF18372.1 KFY04441.1 - 0.11 12.6 0.9 0.29 11.2 0.9 1.7 1 0 0 1 1 1 0 Integrin beta epidermal growth factor like domain 1 EGF PF00008.27 KFY04441.1 - 0.2 12.0 2.2 0.67 10.3 2.2 1.9 1 1 0 1 1 1 0 EGF-like domain EB PF01683.18 KFY04441.1 - 0.25 11.7 3.2 0.46 10.8 3.2 1.3 1 0 0 1 1 1 0 EB module Laminin_EGF PF00053.24 KFY04441.1 - 0.25 11.5 4.3 0.48 10.6 4.3 1.4 1 0 0 1 1 1 0 Laminin EGF domain PHD PF00628.29 KFY04442.1 - 2.8e-07 30.3 12.6 4.5e-07 29.7 12.6 1.3 1 0 0 1 1 1 1 PHD-finger PHD_3 PF13922.6 KFY04442.1 - 7.5 7.0 7.8 0.74 10.2 2.3 2.3 2 0 0 2 2 2 0 PHD domain of transcriptional enhancer, Asx Iso_dh PF00180.20 KFY04444.1 - 4.4e-121 404.3 0.0 5.1e-121 404.1 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase LIM PF00412.22 KFY04445.1 - 0.0028 17.8 8.2 0.0028 17.8 8.2 2.4 2 0 0 2 2 2 1 LIM domain Cation_efflux PF01545.21 KFY04446.1 - 1.1e-47 162.4 8.3 1.3e-47 162.1 8.3 1.1 1 0 0 1 1 1 1 Cation efflux family ZT_dimer PF16916.5 KFY04446.1 - 4.7e-05 23.4 0.0 9e-05 22.5 0.0 1.5 1 0 0 1 1 1 1 Dimerisation domain of Zinc Transporter SIR2 PF02146.17 KFY04447.1 - 8.2e-31 107.3 0.0 1.2e-30 106.8 0.0 1.2 1 0 0 1 1 1 1 Sir2 family DUF5321 PF17254.2 KFY04448.1 - 2.2e-63 212.5 1.0 3e-63 212.0 1.0 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF5321) Stn1 PF10451.9 KFY04448.1 - 0.003 16.6 0.6 0.004 16.2 0.6 1.2 1 0 0 1 1 1 1 Telomere regulation protein Stn1 C1ORF64 PF15547.6 KFY04448.1 - 0.024 15.1 1.6 0.041 14.3 1.6 1.3 1 0 0 1 1 1 0 Steroid receptor-associated and regulated protein IES5 PF17335.2 KFY04448.1 - 0.049 13.9 0.0 0.089 13.1 0.0 1.4 1 0 0 1 1 1 0 Ino80 complex subunit 5 LcrG PF07216.12 KFY04448.1 - 0.26 11.2 2.1 0.6 10.1 2.1 1.6 1 1 0 1 1 1 0 LcrG protein DUF1654 PF07867.11 KFY04448.1 - 0.59 9.9 3.3 0.39 10.5 1.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1654) Mitofilin PF09731.9 KFY04448.1 - 9.7 4.9 12.0 0.36 9.6 1.0 2.0 1 1 1 2 2 2 0 Mitochondrial inner membrane protein Peptidase_C50 PF03568.17 KFY04449.1 - 4.2e-159 529.9 0.0 8e-159 529.0 0.0 1.5 1 0 0 1 1 1 1 Peptidase family C50 TPR_12 PF13424.6 KFY04449.1 - 1.1e-06 28.8 17.3 0.038 14.3 0.2 6.8 5 2 2 7 7 7 4 Tetratricopeptide repeat CHAT PF12770.7 KFY04449.1 - 0.00024 20.6 1.2 0.044 13.2 0.0 3.6 3 1 0 3 3 3 1 CHAT domain TPR_2 PF07719.17 KFY04449.1 - 0.011 15.8 10.7 8.4 6.8 0.1 6.2 7 0 0 7 7 7 0 Tetratricopeptide repeat NTPase_P4 PF11602.8 KFY04449.1 - 0.079 12.2 1.0 4.1 6.5 0.1 3.1 3 0 0 3 3 3 0 ATPase P4 of dsRNA bacteriophage phi-12 TPR_MalT PF17874.1 KFY04449.1 - 0.33 10.3 12.1 0.17 11.2 1.2 4.3 4 1 0 5 5 5 0 MalT-like TPR region TPR_1 PF00515.28 KFY04449.1 - 2.8 7.9 4.8 35 4.4 0.0 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat RRM_1 PF00076.22 KFY04455.1 - 8.1e-08 32.0 0.0 1.2e-07 31.4 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KFY04455.1 - 1.2e-05 25.0 0.0 2e-05 24.3 0.0 1.2 1 0 0 1 1 1 1 Occluded RNA-recognition motif Nup35_RRM_2 PF14605.6 KFY04455.1 - 0.061 13.3 0.0 0.095 12.7 0.0 1.3 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.11 KFY04455.1 - 0.099 12.7 0.1 0.38 10.8 0.0 1.8 2 0 0 2 2 2 0 RNA binding motif Transket_pyr PF02779.24 KFY04456.1 - 1.2e-46 158.6 0.0 2e-46 157.9 0.0 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 KFY04456.1 - 4.6e-36 123.4 0.0 1.4e-35 121.9 0.0 1.9 1 0 0 1 1 1 1 Transketolase, C-terminal domain Sterol_MT_C PF08498.10 KFY04456.1 - 7e-20 71.1 0.0 1.5e-19 70.0 0.0 1.5 1 0 0 1 1 1 1 Sterol methyltransferase C-terminal Methyltransf_11 PF08241.12 KFY04456.1 - 8.3e-18 64.8 0.0 2e-17 63.6 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KFY04456.1 - 3.9e-17 62.8 0.0 9.5e-17 61.5 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KFY04456.1 - 6.1e-16 58.6 0.0 1.3e-15 57.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 KFY04456.1 - 3.7e-12 46.1 0.1 5.9e-12 45.5 0.1 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_23 PF13489.6 KFY04456.1 - 3.8e-10 39.9 0.0 7.5e-10 38.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KFY04456.1 - 3.6e-09 37.2 0.0 1e-08 35.8 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KFY04456.1 - 9.7e-09 34.9 0.0 4.9e-08 32.6 0.0 2.1 3 0 0 3 3 3 1 ubiE/COQ5 methyltransferase family PCMT PF01135.19 KFY04456.1 - 0.00015 21.6 0.1 0.00033 20.5 0.1 1.4 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) PrmA PF06325.13 KFY04456.1 - 0.0007 19.1 0.0 0.0016 17.9 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 KFY04456.1 - 0.0023 17.5 0.0 0.0048 16.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_15 PF09445.10 KFY04456.1 - 0.0088 15.6 0.0 0.016 14.8 0.0 1.4 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Methyltransf_2 PF00891.18 KFY04456.1 - 0.022 14.1 0.0 0.077 12.3 0.0 1.9 2 0 0 2 2 2 0 O-methyltransferase domain Methyltransf_24 PF13578.6 KFY04456.1 - 0.066 14.2 0.0 0.27 12.3 0.0 2.0 2 0 0 2 2 1 0 Methyltransferase domain Methyltransf_32 PF13679.6 KFY04456.1 - 0.071 13.1 0.0 0.18 11.8 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain RrnaAD PF00398.20 KFY04456.1 - 0.095 11.8 0.0 0.21 10.6 0.0 1.5 2 0 0 2 2 2 0 Ribosomal RNA adenine dimethylase Methyltransf_29 PF03141.16 KFY04456.1 - 0.12 10.9 0.0 0.18 10.3 0.0 1.2 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase MetW PF07021.12 KFY04456.1 - 0.14 11.8 0.0 0.26 10.8 0.0 1.5 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW YabA PF06156.13 KFY04456.1 - 0.16 12.7 0.6 0.41 11.3 0.6 1.7 1 0 0 1 1 1 0 Initiation control protein YabA HECT PF00632.25 KFY04461.1 - 1.5e-94 317.0 0.0 2.4e-94 316.3 0.0 1.4 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) UBM PF14377.6 KFY04461.1 - 2.2e-26 90.5 19.2 5.3e-10 38.4 3.1 4.2 3 0 0 3 3 3 3 Ubiquitin binding region DUF913 PF06025.12 KFY04461.1 - 1e-17 64.2 0.0 1e-17 64.2 0.0 5.7 5 1 0 5 5 5 1 Domain of Unknown Function (DUF913) DDHD PF02862.17 KFY04461.1 - 0.65 10.1 3.8 6.4 6.9 0.5 2.6 2 0 0 2 2 2 0 DDHD domain Fringe PF02434.16 KFY04462.1 - 0.00019 20.9 0.1 0.0038 16.7 0.4 2.7 2 1 0 2 2 2 1 Fringe-like PAN_4 PF14295.6 KFY04462.1 - 0.0078 16.1 1.2 0.018 15.0 1.2 1.5 1 0 0 1 1 1 1 PAN domain ANAPC4_WD40 PF12894.7 KFY04463.1 - 4.3e-10 39.8 0.2 0.00073 19.8 0.0 4.3 4 1 1 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 KFY04463.1 - 0.00083 20.1 6.5 0.0034 18.2 0.1 4.6 5 0 0 5 5 5 1 WD domain, G-beta repeat PPTA PF01239.22 KFY04464.1 - 1.1e-31 107.6 13.3 1.6e-06 27.6 0.0 5.5 5 0 0 5 5 5 5 Protein prenyltransferase alpha subunit repeat Ctf8 PF09696.10 KFY04465.1 - 1e-44 152.3 0.0 1.2e-44 152.0 0.0 1.1 1 0 0 1 1 1 1 Ctf8 Ribosomal_S6e PF01092.19 KFY04466.1 - 5.1e-58 194.5 0.7 9.8e-58 193.6 0.0 1.8 2 0 0 2 2 2 1 Ribosomal protein S6e Atg14 PF10186.9 KFY04466.1 - 1.4 8.0 5.8 1.8 7.6 5.8 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Pribosyltran_N PF13793.6 KFY04467.1 - 2.1e-43 146.9 0.3 8.3e-43 145.0 0.0 2.0 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.6 KFY04467.1 - 2.1e-42 145.3 2.0 6.8e-34 117.5 1.2 2.5 1 1 1 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.27 KFY04467.1 - 3.8e-17 62.2 1.4 7.8e-17 61.2 0.7 1.8 2 0 0 2 2 2 1 Phosphoribosyl transferase domain UPRTase PF14681.6 KFY04467.1 - 0.0031 17.0 0.2 0.0053 16.2 0.2 1.3 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase DUF1674 PF07896.12 KFY04468.1 - 1e-18 67.5 3.6 1e-18 67.5 3.6 2.6 2 1 0 2 2 2 1 Protein of unknown function (DUF1674) MSA_2 PF00985.17 KFY04468.1 - 0.056 13.8 2.6 0.067 13.5 2.6 1.1 1 0 0 1 1 1 0 Merozoite Surface Antigen 2 (MSA-2) family Trp_syntA PF00290.20 KFY04469.1 - 9.6e-94 313.0 0.3 1.7e-93 312.2 0.0 1.5 2 0 0 2 2 2 1 Tryptophan synthase alpha chain PALP PF00291.25 KFY04469.1 - 1e-48 166.3 2.2 2e-48 165.3 2.2 1.5 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme AAA PF00004.29 KFY04470.1 - 2.1e-15 57.3 0.0 3.6e-15 56.5 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 KFY04470.1 - 0.0011 19.2 0.2 0.025 14.9 0.0 2.4 1 1 1 2 2 2 1 AAA domain AAA_16 PF13191.6 KFY04470.1 - 0.003 18.0 0.0 0.0064 16.9 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.14 KFY04470.1 - 0.056 13.4 0.0 0.13 12.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_11 PF13086.6 KFY04470.1 - 0.15 11.8 0.0 0.28 10.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain GSHPx PF00255.19 KFY04471.1 - 5.7e-39 132.0 0.0 7.4e-39 131.7 0.0 1.1 1 0 0 1 1 1 1 Glutathione peroxidase AhpC-TSA PF00578.21 KFY04471.1 - 0.049 13.5 0.0 0.13 12.2 0.0 1.8 2 1 0 2 2 2 0 AhpC/TSA family DLH PF01738.18 KFY04472.1 - 3.8e-28 98.5 0.0 6.6e-28 97.8 0.0 1.4 1 1 0 1 1 1 1 Dienelactone hydrolase family MFS_1 PF07690.16 KFY04473.1 - 1.1e-31 110.1 27.4 6.6e-25 87.8 10.6 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KFY04473.1 - 4.8e-06 25.7 3.1 4.8e-06 25.7 3.1 2.4 3 0 0 3 3 3 1 Sugar (and other) transporter OATP PF03137.20 KFY04473.1 - 0.3 9.3 4.5 0.15 10.3 1.4 1.8 1 1 1 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family NatB_MDM20 PF09797.9 KFY04476.1 - 4.4e-55 187.2 0.0 5.7e-54 183.5 0.0 2.0 1 1 0 1 1 1 1 N-acetyltransferase B complex (NatB) non catalytic subunit TPR_19 PF14559.6 KFY04476.1 - 0.35 11.4 1.5 0.79 10.3 1.5 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat Ilm1 PF10311.9 KFY04477.1 - 1.2e-45 155.2 0.4 1.3e-45 155.0 0.4 1.0 1 0 0 1 1 1 1 Increased loss of mitochondrial DNA protein 1 M20_dimer PF07687.14 KFY04478.1 - 2.8e-21 75.5 0.0 4.4e-21 74.8 0.0 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M20 PF01546.28 KFY04478.1 - 2.9e-21 76.1 1.3 8.5e-20 71.3 1.3 2.1 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 Peptidase_M28 PF04389.17 KFY04478.1 - 0.0013 18.5 0.0 0.0033 17.1 0.0 1.6 1 0 0 1 1 1 1 Peptidase family M28 DUF4537 PF15057.6 KFY04478.1 - 0.12 12.3 0.0 12 6.0 0.0 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4537) HAD PF12710.7 KFY04479.1 - 7.9e-06 26.4 0.0 0.0033 17.9 0.0 2.4 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 KFY04479.1 - 0.024 14.7 0.0 1.3 9.1 0.0 2.6 2 1 1 3 3 3 0 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 KFY04479.1 - 0.066 13.5 0.0 0.2 11.9 0.0 2.0 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase SPOB_ab PF14682.6 KFY04479.1 - 0.072 13.2 0.0 0.14 12.2 0.0 1.5 1 0 0 1 1 1 0 Sporulation initiation phospho-transferase B, C-terminal Prenyltrans PF00432.21 KFY04480.1 - 5.3e-35 118.8 4.9 3.2e-08 33.2 0.2 6.0 6 0 0 6 6 6 5 Prenyltransferase and squalene oxidase repeat SQHop_cyclase_C PF13243.6 KFY04480.1 - 6.5e-05 22.2 0.0 0.0095 15.1 0.0 2.6 1 1 3 4 4 4 2 Squalene-hopene cyclase C-terminal domain SQHop_cyclase_N PF13249.6 KFY04480.1 - 0.053 12.6 0.0 0.26 10.4 0.0 2.1 2 0 0 2 2 2 0 Squalene-hopene cyclase N-terminal domain TED_complement PF07678.14 KFY04480.1 - 0.3 10.1 0.3 3.8 6.5 0.0 2.6 3 1 1 4 4 4 0 A-macroglobulin TED domain ThiF PF00899.21 KFY04481.1 - 4.9e-58 196.4 0.0 8.7e-58 195.5 0.0 1.4 1 1 0 1 1 1 1 ThiF family Rhodanese PF00581.20 KFY04481.1 - 5.8e-10 39.6 0.2 1.4e-09 38.4 0.0 1.8 2 0 0 2 2 2 1 Rhodanese-like domain Shikimate_DH PF01488.20 KFY04481.1 - 0.011 15.8 0.0 0.087 12.9 0.0 2.2 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase FAD_binding_3 PF01494.19 KFY04481.1 - 0.15 11.3 0.7 0.22 10.7 0.7 1.2 1 0 0 1 1 1 0 FAD binding domain UDPG_MGDP_dh_N PF03721.14 KFY04481.1 - 0.21 11.1 0.1 0.32 10.5 0.1 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain GIDA PF01134.22 KFY04481.1 - 0.31 10.1 1.1 0.48 9.4 1.1 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A Pam17 PF08566.10 KFY04482.1 - 1.7e-65 219.9 0.0 2.2e-65 219.5 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial import protein Pam17 Ribonuclease_3 PF00636.26 KFY04483.1 - 4.6e-40 136.5 0.0 5.5e-22 78.4 0.0 2.8 2 0 0 2 2 2 2 Ribonuclease III domain Ribonucleas_3_3 PF14622.6 KFY04483.1 - 7.4e-26 90.8 0.1 2.8e-11 43.7 0.0 3.7 3 1 0 3 3 3 3 Ribonuclease-III-like Dicer_dimer PF03368.14 KFY04483.1 - 1.6e-23 82.7 0.1 5.1e-23 81.1 0.1 2.0 1 0 0 1 1 1 1 Dicer dimerisation domain DEAD PF00270.29 KFY04483.1 - 9.4e-17 61.3 0.0 1.8e-16 60.4 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KFY04483.1 - 3.4e-15 56.3 0.1 8.5e-15 55.1 0.1 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KFY04483.1 - 5.1e-14 52.6 0.0 1.1e-13 51.6 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit YacG PF03884.14 KFY04483.1 - 0.079 12.7 0.0 0.22 11.3 0.0 1.7 1 0 0 1 1 1 0 DNA gyrase inhibitor YacG Piwi PF02171.17 KFY04484.1 - 2.2e-73 247.1 0.0 3.6e-73 246.5 0.0 1.3 1 0 0 1 1 1 1 Piwi domain ArgoN PF16486.5 KFY04484.1 - 2.7e-21 76.6 0.0 6.6e-21 75.4 0.0 1.7 1 0 0 1 1 1 1 N-terminal domain of argonaute ArgoL1 PF08699.10 KFY04484.1 - 3.3e-13 49.1 0.4 8.8e-13 47.7 0.4 1.8 1 0 0 1 1 1 1 Argonaute linker 1 domain ArgoL2 PF16488.5 KFY04484.1 - 1.6e-11 44.3 0.1 4.5e-11 42.9 0.1 1.8 1 0 0 1 1 1 1 Argonaute linker 2 domain PAZ PF02170.22 KFY04484.1 - 1.9e-07 31.0 0.0 4e-07 29.9 0.0 1.5 1 0 0 1 1 1 1 PAZ domain ArgoMid PF16487.5 KFY04484.1 - 0.0022 18.2 0.1 0.0053 17.0 0.1 1.6 1 0 0 1 1 1 1 Mid domain of argonaute ADH_zinc_N PF00107.26 KFY04485.1 - 5.2e-09 36.2 0.1 1.2e-08 35.0 0.1 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KFY04485.1 - 1.1e-07 31.7 1.5 1.3e-06 28.3 0.2 2.6 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain NAD_Gly3P_dh_C PF07479.14 KFY04486.1 - 7.3e-44 149.5 0.0 1.1e-43 148.9 0.0 1.3 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus NAD_Gly3P_dh_N PF01210.23 KFY04486.1 - 2.7e-43 147.7 0.1 7e-43 146.3 0.0 1.7 2 0 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus PEP_mutase PF13714.6 KFY04487.1 - 2.2e-57 194.3 0.0 2.9e-57 193.9 0.0 1.1 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase QRPTase_C PF01729.19 KFY04487.1 - 0.043 13.6 0.1 0.089 12.6 0.1 1.6 1 1 0 1 1 1 0 Quinolinate phosphoribosyl transferase, C-terminal domain CAP PF00188.26 KFY04488.1 - 3.4e-17 63.4 6.5 1.2e-16 61.7 6.5 1.8 1 1 0 1 1 1 1 Cysteine-rich secretory protein family Cullin PF00888.22 KFY04488.1 - 0.28 9.8 0.1 0.35 9.4 0.1 1.0 1 0 0 1 1 1 0 Cullin family Glyco_transf_20 PF00982.21 KFY04489.1 - 1.4e-162 541.7 0.5 1.9e-162 541.3 0.5 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.16 KFY04489.1 - 2.6e-39 134.8 0.0 4.6e-39 133.9 0.0 1.4 1 0 0 1 1 1 1 Trehalose-phosphatase Glyco_transf_5 PF08323.11 KFY04489.1 - 0.036 13.8 0.2 0.066 12.9 0.2 1.4 1 0 0 1 1 1 0 Starch synthase catalytic domain DGF-1_C PF11040.8 KFY04489.1 - 0.11 12.5 0.2 0.3 11.1 0.2 1.7 1 0 0 1 1 1 0 Dispersed gene family protein 1 of Trypanosoma cruzi C-terminus WD40 PF00400.32 KFY04490.1 - 6.6e-53 175.5 37.1 1e-10 42.0 1.1 9.3 8 1 0 8 8 8 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFY04490.1 - 2.1e-22 79.2 2.8 0.0015 18.7 0.1 7.1 2 2 3 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 KFY04490.1 - 1e-06 28.8 0.0 0.034 14.0 0.0 3.7 2 2 1 4 4 4 3 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.8 KFY04490.1 - 5.1e-05 22.1 1.9 0.037 12.7 0.2 3.6 3 1 1 4 4 4 1 Nucleoporin Nup120/160 NLE PF08154.12 KFY04490.1 - 8.1e-05 23.1 0.0 0.00016 22.1 0.0 1.5 1 0 0 1 1 1 1 NLE (NUC135) domain WD40_like PF17005.5 KFY04490.1 - 0.00023 20.6 0.0 0.53 9.6 0.0 3.8 4 0 0 4 4 4 1 WD40-like domain Ge1_WD40 PF16529.5 KFY04490.1 - 0.0004 19.4 0.2 7.3 5.5 0.0 4.0 2 2 1 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein FAD_binding_9 PF08021.11 KFY04490.1 - 0.0085 16.3 0.0 3.7 7.8 0.0 2.7 2 1 0 2 2 2 2 Siderophore-interacting FAD-binding domain Nucleoporin_N PF08801.11 KFY04490.1 - 0.012 14.4 0.3 0.68 8.6 0.1 2.6 2 2 0 2 2 2 0 Nup133 N terminal like TFIIIC_delta PF12657.7 KFY04490.1 - 0.088 12.7 3.9 4.3 7.2 0.7 3.9 2 2 1 3 3 3 0 Transcription factor IIIC subunit delta N-term PD40 PF07676.12 KFY04490.1 - 0.091 12.7 3.4 44 4.2 0.1 4.4 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat MutS_V PF00488.21 KFY04491.1 - 1.9e-48 165.0 3.2 1.4e-45 155.6 3.2 2.5 1 1 0 1 1 1 1 MutS domain V MutS_III PF05192.18 KFY04491.1 - 9.9e-30 104.2 1.8 9.9e-30 104.2 1.8 1.9 2 0 0 2 2 2 1 MutS domain III MutS_II PF05188.17 KFY04491.1 - 1.9e-08 34.7 0.1 6.5e-08 32.9 0.0 2.0 2 0 0 2 2 2 1 MutS domain II MutS_IV PF05190.18 KFY04491.1 - 1.2e-07 31.9 0.3 4e-07 30.3 0.3 2.0 1 0 0 1 1 1 1 MutS family domain IV AAA_27 PF13514.6 KFY04491.1 - 0.0017 18.0 0.2 0.63 9.6 0.0 2.6 2 0 0 2 2 2 2 AAA domain Vpu PF00558.19 KFY04491.1 - 2.3 8.1 7.4 1.3 8.9 2.1 2.7 2 1 1 3 3 3 0 Vpu protein G-patch PF01585.23 KFY04492.1 - 4.3e-06 26.5 0.0 1.7e-05 24.6 0.0 2.1 1 1 0 1 1 1 1 G-patch domain Utp14 PF04615.13 KFY04492.1 - 0.0013 17.5 34.1 0.0016 17.1 34.1 1.1 1 0 0 1 1 1 1 Utp14 protein DUF936 PF06075.12 KFY04492.1 - 0.1 11.5 33.8 0.14 11.1 33.8 1.2 1 0 0 1 1 1 0 Plant protein of unknown function (DUF936) GREB1 PF15782.5 KFY04492.1 - 3.1 4.8 26.7 4.1 4.4 26.7 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Macoilin PF09726.9 KFY04492.1 - 5.9 5.3 31.5 8.3 4.8 31.5 1.2 1 0 0 1 1 1 0 Macoilin family PemK_toxin PF02452.17 KFY04497.1 - 3.7e-05 24.1 0.0 0.00011 22.6 0.0 1.7 1 1 0 1 1 1 1 PemK-like, MazF-like toxin of type II toxin-antitoxin system OTT_1508_deam PF14441.6 KFY04498.1 - 1.5e-17 63.3 0.5 1.5e-17 63.3 0.5 2.9 2 0 0 2 2 2 1 OTT_1508-like deaminase DUF4363 PF14276.6 KFY04498.1 - 0.011 15.8 0.4 0.14 12.3 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4363) Mucin PF01456.17 KFY04501.1 - 0.005 16.8 0.0 0.0058 16.6 0.0 1.3 1 0 0 1 1 1 1 Mucin-like glycoprotein Folate_carrier PF01770.18 KFY04501.1 - 0.25 10.1 0.0 0.39 9.4 0.0 1.2 1 0 0 1 1 1 0 Reduced folate carrier 2OG-FeII_Oxy_3 PF13640.6 KFY04502.1 - 6.2e-10 39.8 0.0 1.4e-09 38.7 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DAO PF01266.24 KFY04503.1 - 5.4e-54 184.1 2.0 7.9e-54 183.5 2.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 KFY04503.1 - 1.3e-06 28.5 0.2 3e-06 27.4 0.2 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 KFY04503.1 - 0.00041 19.7 0.2 0.00075 18.8 0.2 1.3 1 0 0 1 1 1 1 Thi4 family Trp_halogenase PF04820.14 KFY04503.1 - 0.0016 17.4 0.1 0.0022 16.9 0.1 1.2 1 0 0 1 1 1 1 Tryptophan halogenase Pyr_redox_2 PF07992.14 KFY04503.1 - 0.0023 17.2 0.0 0.011 15.0 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KFY04503.1 - 0.015 15.8 0.0 0.043 14.4 0.0 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KFY04503.1 - 0.017 15.1 0.2 0.04 13.9 0.1 1.6 2 0 0 2 2 2 0 FAD-NAD(P)-binding MCRA PF06100.11 KFY04503.1 - 0.061 12.1 0.1 0.085 11.6 0.1 1.1 1 0 0 1 1 1 0 MCRA family GMC_oxred_N PF00732.19 KFY04503.1 - 0.15 11.4 0.0 2.6 7.3 0.0 2.1 2 0 0 2 2 2 0 GMC oxidoreductase DUF2014 PF09427.10 KFY04504.1 - 1.1e-90 303.6 1.0 1.8e-90 302.9 1.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF2014) Sterol-sensing PF12349.8 KFY04504.1 - 1.9e-27 96.0 6.9 2.1e-27 95.9 5.3 1.9 2 0 0 2 2 2 1 Sterol-sensing domain of SREBP cleavage-activation HLH PF00010.26 KFY04504.1 - 5.6e-13 48.6 0.1 1.5e-12 47.2 0.1 1.8 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Patched PF02460.18 KFY04504.1 - 0.00094 17.4 2.7 0.0015 16.7 2.7 1.2 1 0 0 1 1 1 1 Patched family Sugar_tr PF00083.24 KFY04505.1 - 1e-43 149.9 14.6 1.5e-43 149.4 14.6 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KFY04505.1 - 3.8e-32 111.6 31.6 6.8e-32 110.8 31.6 1.4 1 0 0 1 1 1 1 Major Facilitator Superfamily ATG22 PF11700.8 KFY04505.1 - 0.0043 15.7 2.4 0.0043 15.7 2.4 2.4 2 0 0 2 2 2 1 Vacuole effluxer Atg22 like DBD_Tnp_Hermes PF10683.9 KFY04505.1 - 0.051 13.3 0.1 0.11 12.2 0.1 1.4 1 0 0 1 1 1 0 Hermes transposase DNA-binding domain DUF737 PF05300.11 KFY04507.1 - 0.012 16.0 4.9 0.015 15.6 4.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF737) bZIP_1 PF00170.21 KFY04507.1 - 0.026 14.6 7.5 0.051 13.7 7.5 1.5 1 0 0 1 1 1 0 bZIP transcription factor Bul1_N PF04425.12 KFY04508.1 - 2.5e-06 26.6 0.3 0.013 14.3 0.8 2.3 2 0 0 2 2 2 2 Bul1 N terminus Bul1_C PF04426.12 KFY04508.1 - 4.8e-05 22.9 0.0 7.1e-05 22.4 0.0 1.2 1 0 0 1 1 1 1 Bul1 C terminus FAD_binding_3 PF01494.19 KFY04509.1 - 3.6e-12 46.2 0.1 4.9e-08 32.6 0.0 2.6 2 1 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 KFY04509.1 - 0.00017 21.7 0.0 0.00038 20.6 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KFY04509.1 - 0.00038 19.8 0.0 0.0015 17.8 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KFY04509.1 - 0.00047 19.9 0.1 0.00081 19.1 0.1 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 KFY04509.1 - 0.047 12.7 0.1 0.087 11.9 0.1 1.4 1 0 0 1 1 1 0 Lycopene cyclase protein Thi4 PF01946.17 KFY04509.1 - 0.11 11.7 0.1 0.19 10.9 0.1 1.3 1 0 0 1 1 1 0 Thi4 family AlaDh_PNT_C PF01262.21 KFY04509.1 - 0.16 11.2 0.0 0.34 10.2 0.0 1.5 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox PF00070.27 KFY04509.1 - 0.18 12.4 0.1 0.44 11.1 0.1 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Aldo_ket_red PF00248.21 KFY04510.1 - 9.5e-73 245.0 0.0 1.1e-72 244.8 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family FAD_binding_3 PF01494.19 KFY04511.1 - 4.2e-36 124.9 0.0 9.9e-36 123.7 0.0 1.5 1 1 0 1 1 1 1 FAD binding domain Lycopene_cycl PF05834.12 KFY04511.1 - 0.0091 15.1 0.0 1.6 7.7 0.0 2.2 2 0 0 2 2 2 2 Lycopene cyclase protein Pyr_redox_3 PF13738.6 KFY04511.1 - 0.057 12.7 0.1 6.7 5.9 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Glyoxalase PF00903.25 KFY04512.1 - 3e-11 43.6 2.4 7e-10 39.2 1.9 2.5 2 1 0 2 2 2 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 KFY04512.1 - 0.0018 18.6 0.1 0.0097 16.2 0.1 2.2 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily FAA_hydrolase PF01557.18 KFY04513.1 - 1.3e-50 172.1 0.0 2.3e-50 171.3 0.0 1.3 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family Fungal_trans PF04082.18 KFY04513.1 - 9.3e-17 60.9 0.9 1.5e-16 60.3 0.9 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-H2C2_2 PF13465.6 KFY04513.1 - 1.3e-05 25.4 3.5 1.3e-05 25.4 3.5 2.6 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2 PF00096.26 KFY04513.1 - 0.0012 19.2 21.8 0.023 15.1 4.6 3.2 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 KFY04513.1 - 0.0075 17.0 2.3 0.0075 17.0 2.3 3.5 3 0 0 3 3 3 2 C2H2-type zinc finger PyrI_C PF02748.15 KFY04513.1 - 1.2 9.1 3.1 1.7 8.6 0.1 2.3 2 0 0 2 2 2 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain zf-C2H2_jaz PF12171.8 KFY04513.1 - 6 7.3 15.3 0.66 10.3 1.9 3.1 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-BED PF02892.15 KFY04513.1 - 8.3 6.5 7.1 23 5.1 1.5 2.6 1 1 1 2 2 2 0 BED zinc finger zf-C2H2_6 PF13912.6 KFY04513.1 - 9.2 6.4 12.0 0.57 10.3 1.1 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger TRI12 PF06609.13 KFY04514.1 - 1.8e-26 92.8 11.0 2.3e-26 92.4 11.0 1.0 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.16 KFY04514.1 - 1.6e-22 80.0 40.8 2.3e-19 69.5 36.7 3.0 2 1 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KFY04514.1 - 1.3e-10 40.7 0.4 1.3e-10 40.7 0.4 2.8 3 1 0 3 3 3 1 Sugar (and other) transporter YtpI PF14007.6 KFY04514.1 - 3.5 7.8 7.1 0.91 9.7 0.0 3.1 3 0 0 3 3 3 0 YtpI-like protein Ank_2 PF12796.7 KFY04515.1 - 4.9e-23 81.5 0.4 6.2e-08 33.1 0.0 3.7 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.30 KFY04515.1 - 9.8e-16 57.4 4.1 0.0023 18.3 0.1 5.7 5 0 0 5 5 5 4 Ankyrin repeat Ank_4 PF13637.6 KFY04515.1 - 3.7e-15 56.1 2.4 0.00012 22.6 0.1 5.0 2 1 2 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFY04515.1 - 1e-14 53.1 3.4 0.49 11.1 0.0 7.8 7 0 0 7 7 7 4 Ankyrin repeat Ank_5 PF13857.6 KFY04515.1 - 1.5e-14 53.8 3.5 9.1e-05 22.7 0.1 4.9 4 1 2 6 6 6 3 Ankyrin repeats (many copies) Helo_like_N PF17111.5 KFY04515.1 - 8.9e-05 22.0 0.3 0.00022 20.6 0.3 1.7 1 0 0 1 1 1 1 Fungal N-terminal domain of STAND proteins PQ-loop PF04193.14 KFY04516.1 - 0.00021 21.0 1.2 0.00021 21.0 1.2 2.8 3 0 0 3 3 3 1 PQ loop repeat MtN3_slv PF03083.16 KFY04516.1 - 0.0062 16.6 2.2 0.053 13.6 0.3 2.7 2 0 0 2 2 2 1 Sugar efflux transporter for intercellular exchange DUF2157 PF09925.9 KFY04516.1 - 5.1 6.9 9.6 0.31 10.8 2.6 2.3 2 1 0 2 2 2 0 Predicted membrane protein (DUF2157) RGS PF00615.19 KFY04517.1 - 4.3e-10 39.9 0.0 6.8e-10 39.3 0.0 1.2 1 0 0 1 1 1 1 Regulator of G protein signaling domain DUF3295 PF11702.8 KFY04521.1 - 8.3e-116 388.3 52.4 1.7e-94 318.0 30.6 2.5 1 1 1 2 2 2 2 Protein of unknown function (DUF3295) APH PF01636.23 KFY04524.1 - 1.8e-18 67.4 0.0 3.1e-18 66.6 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family APH PF01636.23 KFY04525.1 - 2.3e-21 76.8 0.0 3.3e-21 76.3 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family TPR_12 PF13424.6 KFY04526.1 - 9.9e-73 240.4 32.6 1.1e-15 57.7 1.5 5.4 1 1 5 6 6 6 6 Tetratricopeptide repeat TPR_10 PF13374.6 KFY04526.1 - 3.8e-64 211.0 9.2 1.4e-11 43.8 0.0 7.7 7 0 0 7 7 7 7 Tetratricopeptide repeat TPR_7 PF13176.6 KFY04526.1 - 5.8e-15 54.2 5.6 0.13 12.3 0.0 7.0 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_2 PF07719.17 KFY04526.1 - 2.4e-13 49.1 6.3 0.068 13.3 0.5 7.3 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_1 PF00515.28 KFY04526.1 - 3.8e-13 48.7 4.1 0.067 13.0 0.3 6.5 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_8 PF13181.6 KFY04526.1 - 7e-12 44.6 4.0 0.6 10.5 0.0 6.0 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_16 PF13432.6 KFY04526.1 - 5.7e-10 39.7 5.5 0.041 14.5 0.0 6.2 4 2 0 5 5 5 3 Tetratricopeptide repeat TPR_4 PF07721.14 KFY04526.1 - 5.7e-09 35.7 0.5 0.65 10.8 0.4 6.6 7 0 0 7 7 6 1 Tetratricopeptide repeat TPR_MalT PF17874.1 KFY04526.1 - 9.3e-09 35.1 13.2 8e-08 32.0 5.7 2.5 1 1 1 2 2 2 2 MalT-like TPR region NB-ARC PF00931.22 KFY04526.1 - 1.5e-06 27.6 0.0 0.009 15.2 0.0 2.3 2 0 0 2 2 2 2 NB-ARC domain TPR_19 PF14559.6 KFY04526.1 - 2.2e-05 24.9 6.0 1.3 9.6 0.0 5.8 3 2 3 6 6 6 3 Tetratricopeptide repeat ANAPC3 PF12895.7 KFY04526.1 - 3.4e-05 24.0 0.5 2 8.7 0.0 4.9 1 1 3 4 4 4 1 Anaphase-promoting complex, cyclosome, subunit 3 AAA_16 PF13191.6 KFY04526.1 - 0.00055 20.3 0.2 0.0026 18.2 0.2 2.2 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 KFY04526.1 - 0.0012 19.2 0.0 0.039 14.2 0.0 2.7 2 0 0 2 2 2 1 AAA domain TPR_14 PF13428.6 KFY04526.1 - 0.0023 18.6 15.3 9.1 7.4 0.1 7.4 7 1 1 8 8 7 1 Tetratricopeptide repeat TPR_17 PF13431.6 KFY04526.1 - 0.0049 17.1 1.9 27 5.4 0.0 5.5 6 0 0 6 6 6 0 Tetratricopeptide repeat DUF676 PF05057.14 KFY04526.1 - 0.051 13.1 0.0 0.14 11.7 0.0 1.6 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Abhydrolase_6 PF12697.7 KFY04526.1 - 0.13 12.9 0.0 0.87 10.1 0.0 2.3 2 0 0 2 2 2 0 Alpha/beta hydrolase family Sugar_tr PF00083.24 KFY04527.1 - 1.4e-75 254.9 32.7 1.7e-75 254.6 32.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KFY04527.1 - 6e-21 74.8 37.0 6e-21 74.8 37.0 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 KFY04527.1 - 0.16 10.3 9.3 0.61 8.3 3.5 2.6 1 1 1 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family p450 PF00067.22 KFY04528.1 - 1.1e-60 205.7 0.0 1.5e-60 205.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Chromo PF00385.24 KFY04532.1 - 0.0026 17.6 0.1 0.0046 16.8 0.1 1.4 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain CRAL_TRIO PF00650.20 KFY04533.1 - 1.3e-26 93.3 0.0 1.8e-26 92.7 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 KFY04533.1 - 1.4e-10 41.2 0.2 3.4e-10 40.0 0.2 1.7 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain AIF_C PF14721.6 KFY04533.1 - 0.018 15.4 0.2 0.067 13.6 0.2 2.0 1 1 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term Rad4 PF03835.15 KFY04534.1 - 1.9e-33 115.3 0.2 6.4e-33 113.5 0.2 2.0 1 0 0 1 1 1 1 Rad4 transglutaminase-like domain BHD_3 PF10405.9 KFY04534.1 - 3.9e-28 97.7 0.1 8.5e-28 96.6 0.1 1.6 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 3 BHD_1 PF10403.9 KFY04534.1 - 4.1e-17 61.8 0.2 1.2e-16 60.2 0.2 1.9 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 1 BHD_2 PF10404.9 KFY04534.1 - 1e-15 58.4 0.7 1e-15 58.4 0.7 4.5 5 0 0 5 5 5 1 Rad4 beta-hairpin domain 2 CorA PF01544.18 KFY04534.1 - 5.3e-13 48.9 3.4 8e-11 41.8 0.6 2.3 2 0 0 2 2 2 2 CorA-like Mg2+ transporter protein Transglut_core PF01841.19 KFY04534.1 - 0.022 15.2 0.0 0.077 13.5 0.0 1.9 1 0 0 1 1 1 0 Transglutaminase-like superfamily DUF2207 PF09972.9 KFY04534.1 - 0.13 11.0 0.1 0.23 10.2 0.1 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) zf-AN1 PF01428.16 KFY04535.1 - 2.2e-23 82.1 23.3 6.6e-12 45.4 8.2 2.2 2 0 0 2 2 2 2 AN1-like Zinc finger zf-C5HC2 PF02928.16 KFY04535.1 - 0.00071 19.9 6.8 0.26 11.7 0.8 2.4 2 0 0 2 2 2 2 C5HC2 zinc finger IBR PF01485.21 KFY04535.1 - 0.0078 16.4 16.7 0.016 15.4 4.2 2.4 2 0 0 2 2 2 2 IBR domain, a half RING-finger domain C1_4 PF07975.12 KFY04535.1 - 5.5 7.3 12.3 4.9 7.5 4.9 2.7 2 0 0 2 2 2 0 TFIIH C1-like domain Transp_Tc5_C PF04236.15 KFY04535.1 - 7.7 7.0 13.5 6.2 7.3 1.0 2.3 2 0 0 2 2 2 0 Tc5 transposase C-terminal domain HIT PF01230.23 KFY04536.1 - 3.2e-13 50.3 0.0 9e-13 48.8 0.0 1.8 1 1 0 1 1 1 1 HIT domain DcpS_C PF11969.8 KFY04536.1 - 0.0048 17.4 0.1 0.041 14.4 0.1 2.2 1 1 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding CwfJ_C_1 PF04677.15 KFY04536.1 - 0.011 15.6 0.7 0.046 13.6 0.0 2.1 2 1 0 2 2 2 0 Protein similar to CwfJ C-terminus 1 ATP_transf PF09830.9 KFY04536.1 - 0.16 12.2 0.7 15 5.8 0.0 3.7 3 1 1 4 4 4 0 ATP adenylyltransferase ATP19 PF11022.8 KFY04537.1 - 8e-25 87.0 0.0 9.5e-25 86.8 0.0 1.1 1 0 0 1 1 1 1 ATP synthase subunit K Glyco_hydro_2 PF00703.21 KFY04540.1 - 9.2e-13 48.8 0.4 2.6e-12 47.4 0.1 2.0 2 0 0 2 2 2 1 Glycosyl hydrolases family 2 Mannosidase_ig PF17786.1 KFY04540.1 - 2.6e-07 31.1 0.9 1.3e-06 28.9 0.1 2.4 2 0 0 2 2 2 1 Mannosidase Ig/CBM-like domain Ig_mannosidase PF17753.1 KFY04540.1 - 0.0022 17.7 0.0 0.0056 16.4 0.0 1.6 1 0 0 1 1 1 1 Ig-fold domain Glyco_hydro_2_C PF02836.17 KFY04540.1 - 0.0054 15.9 0.0 0.0094 15.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Glyco_hydro_2_N PF02837.18 KFY04540.1 - 0.014 15.3 0.0 0.034 14.0 0.0 1.6 1 0 0 1 1 1 0 Glycosyl hydrolases family 2, sugar binding domain Zn_clus PF00172.18 KFY04541.1 - 1.3e-06 28.5 6.9 2.6e-06 27.4 6.9 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain FixP_N PF14715.6 KFY04541.1 - 0.55 10.0 0.1 0.55 10.0 0.1 1.9 2 0 0 2 2 2 0 N-terminal domain of cytochrome oxidase-cbb3, FixP Glyco_hydro_3 PF00933.21 KFY04542.1 - 6.2e-50 170.4 0.0 7.6e-50 170.1 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain SBD_N PF07005.11 KFY04542.1 - 0.015 15.1 0.1 0.028 14.2 0.1 1.5 1 0 0 1 1 1 0 Sugar-binding N-terminal domain DUF1343 PF07075.11 KFY04543.1 - 2.2e-118 395.7 0.0 2.5e-118 395.5 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1343) MFS_1 PF07690.16 KFY04544.1 - 4.8e-28 98.1 20.9 4.8e-28 98.1 20.9 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily DUF4131 PF13567.6 KFY04544.1 - 0.18 11.4 0.1 0.18 11.4 0.1 3.2 4 1 1 5 5 5 0 Domain of unknown function (DUF4131) AnmK PF03702.14 KFY04545.1 - 7.7e-75 252.3 0.0 9.1e-75 252.0 0.0 1.0 1 0 0 1 1 1 1 Anhydro-N-acetylmuramic acid kinase Ank_2 PF12796.7 KFY04546.1 - 1.2e-45 153.9 0.0 2.4e-09 37.6 0.0 5.3 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KFY04546.1 - 7e-36 121.8 3.4 1.6e-06 28.3 0.0 9.0 4 2 5 9 9 9 8 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFY04546.1 - 1.8e-34 113.9 0.0 0.0042 17.5 0.0 9.4 9 0 0 9 9 9 8 Ankyrin repeat Ank_4 PF13637.6 KFY04546.1 - 3.2e-34 116.9 0.0 8.2e-06 26.3 0.0 5.8 5 2 0 5 5 5 5 Ankyrin repeats (many copies) Ank PF00023.30 KFY04546.1 - 4.5e-29 99.6 0.1 0.042 14.3 0.1 9.5 9 0 0 9 9 9 7 Ankyrin repeat DUF3734 PF12536.8 KFY04546.1 - 0.077 13.3 0.0 27 5.2 0.0 3.4 2 1 1 3 3 3 0 Patatin phospholipase DUF4926 PF16277.5 KFY04546.1 - 0.091 12.1 0.1 7.3 6.0 0.0 3.0 2 1 1 3 3 3 0 Domain of unknown function (DUF4926) PMR5N PF14416.6 KFY04546.1 - 0.092 13.1 0.2 3.8 7.9 0.0 2.9 3 0 0 3 3 3 0 PMR5 N terminal Domain HA PF03457.14 KFY04546.1 - 0.15 12.4 0.2 22 5.5 0.0 4.0 4 1 0 4 4 4 0 Helicase associated domain Sugar_tr PF00083.24 KFY04552.1 - 9e-90 301.7 24.6 1.1e-89 301.5 24.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KFY04552.1 - 8.6e-31 107.1 45.7 6.4e-28 97.7 24.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Glyco_hydro_28 PF00295.17 KFY04553.1 - 1e-41 143.1 7.7 1.5e-41 142.5 7.7 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 Pectinesterase PF01095.19 KFY04554.1 - 3.3e-42 144.2 9.7 4.2e-42 143.9 9.7 1.0 1 0 0 1 1 1 1 Pectinesterase Glyco_hydro_28 PF00295.17 KFY04555.1 - 2.8e-42 144.9 8.6 3.6e-42 144.6 8.6 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 Beta_helix PF13229.6 KFY04555.1 - 3.9e-06 26.8 5.6 1e-05 25.4 5.6 1.7 1 0 0 1 1 1 1 Right handed beta helix region Glyco_hydro_43 PF04616.14 KFY04556.1 - 3.8e-74 249.6 0.0 5.1e-74 249.2 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 GH43_C2 PF17851.1 KFY04556.1 - 6.6e-16 58.6 0.0 1.1e-15 57.9 0.0 1.3 1 0 0 1 1 1 1 Beta xylosidase C-terminal Concanavalin A-like domain Fungal_trans PF04082.18 KFY04557.1 - 9.8e-15 54.3 0.4 1.6e-14 53.6 0.4 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Abhydrolase_3 PF07859.13 KFY04558.1 - 2.4e-35 122.3 0.0 3.1e-35 122.0 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 KFY04558.1 - 3.8e-13 49.0 0.0 4.7e-13 48.8 0.0 1.1 1 0 0 1 1 1 1 Steryl acetyl hydrolase Peptidase_S9 PF00326.21 KFY04558.1 - 4.5e-06 26.3 0.0 0.0042 16.6 0.0 2.3 2 0 0 2 2 2 2 Prolyl oligopeptidase family BAAT_C PF08840.11 KFY04558.1 - 0.037 13.9 0.0 0.058 13.3 0.0 1.2 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal COesterase PF00135.28 KFY04558.1 - 0.075 11.9 0.0 4 6.2 0.0 2.1 2 0 0 2 2 2 0 Carboxylesterase family Transposase_23 PF03017.14 KFY04562.1 - 0.15 12.0 0.0 2 8.4 0.0 2.2 2 0 0 2 2 2 0 TNP1/EN/SPM transposase Peptidase_C12 PF01088.21 KFY04564.1 - 9.8e-47 159.4 0.0 1.2e-46 159.2 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 PALP PF00291.25 KFY04565.1 - 2.5e-79 266.7 0.5 3.1e-79 266.5 0.5 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Thr_dehydrat_C PF00585.18 KFY04565.1 - 4.2e-42 141.8 0.0 3.4e-21 74.8 0.0 2.3 2 0 0 2 2 2 2 C-terminal regulatory domain of Threonine dehydratase HIG_1_N PF04588.13 KFY04566.1 - 2.4e-23 82.1 0.1 3.6e-23 81.5 0.1 1.3 1 0 0 1 1 1 1 Hypoxia induced protein conserved region DUF2514 PF10721.9 KFY04566.1 - 0.11 12.5 7.5 0.065 13.3 5.3 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2514) TPX2 PF06886.11 KFY04566.1 - 0.95 9.7 19.9 0.41 10.9 14.7 2.5 2 0 0 2 2 2 0 Targeting protein for Xklp2 (TPX2) Trypan_PARP PF05887.11 KFY04567.1 - 0.00027 20.9 12.3 0.00058 19.9 12.3 1.5 1 0 0 1 1 1 1 Procyclic acidic repetitive protein (PARP) SPESP1 PF15754.5 KFY04567.1 - 0.011 15.0 2.6 0.016 14.4 2.6 1.2 1 0 0 1 1 1 0 Sperm equatorial segment protein 1 VWA PF00092.28 KFY04570.1 - 0.01 16.1 0.0 0.015 15.5 0.0 1.2 1 0 0 1 1 1 0 von Willebrand factor type A domain VWA_2 PF13519.6 KFY04570.1 - 0.12 13.1 0.0 0.25 12.0 0.0 1.7 1 1 0 1 1 1 0 von Willebrand factor type A domain Acyl-CoA_dh_M PF02770.19 KFY04571.1 - 2.5e-05 24.4 0.0 4.7e-05 23.5 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain F-box PF00646.33 KFY04572.1 - 0.014 15.2 0.2 0.049 13.5 0.2 1.9 1 0 0 1 1 1 0 F-box domain Sugar_tr PF00083.24 KFY04575.1 - 8.2e-82 275.5 33.9 9.2e-82 275.3 33.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KFY04575.1 - 3.5e-30 105.1 54.5 5.8e-25 87.9 29.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KFY04576.1 - 1e-59 202.6 13.2 1e-59 202.6 13.2 1.3 1 1 1 2 2 2 1 Sugar (and other) transporter MFS_1 PF07690.16 KFY04576.1 - 2.5e-12 46.4 27.7 4e-07 29.3 3.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF4913 PF16259.5 KFY04576.1 - 0.071 13.2 0.3 0.15 12.1 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4913) Histidinol_dh PF00815.20 KFY04577.1 - 1.6e-138 462.2 3.2 2e-138 461.9 3.2 1.0 1 0 0 1 1 1 1 Histidinol dehydrogenase Zn_clus PF00172.18 KFY04578.1 - 2.9e-06 27.3 9.4 5.1e-06 26.5 9.4 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KFY04578.1 - 0.0014 17.7 0.3 0.0042 16.2 0.3 1.7 1 1 0 1 1 1 1 Fungal specific transcription factor domain Rad1 PF02144.16 KFY04581.1 - 2.2e-76 256.5 1.2 2.8e-76 256.2 1.2 1.1 1 0 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 Ost5 PF05251.12 KFY04581.1 - 8.7e-11 41.9 3.4 8.7e-11 41.9 3.4 2.5 2 0 0 2 2 2 1 Oligosaccharyltransferase subunit 5 Bromodomain PF00439.25 KFY04582.1 - 1.8e-24 85.6 0.5 4.6e-24 84.3 0.5 1.7 1 0 0 1 1 1 1 Bromodomain Acetyltransf_1 PF00583.25 KFY04582.1 - 7.3e-08 32.7 0.0 1.3e-07 31.8 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 KFY04582.1 - 1.8e-07 31.1 0.4 9.9e-07 28.8 0.2 2.2 1 1 1 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 KFY04582.1 - 0.00033 21.0 0.4 0.00066 20.1 0.1 1.6 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KFY04582.1 - 0.21 11.6 0.0 0.41 10.7 0.0 1.5 1 0 0 1 1 1 0 FR47-like protein ABC_membrane_2 PF06472.15 KFY04583.1 - 1.2e-90 303.6 1.2 2.3e-88 296.1 0.2 2.5 3 0 0 3 3 3 2 ABC transporter transmembrane region 2 ABC_tran PF00005.27 KFY04583.1 - 4e-14 53.3 0.0 1.1e-13 51.8 0.0 1.8 2 0 0 2 2 2 1 ABC transporter AAA_21 PF13304.6 KFY04583.1 - 0.029 14.2 0.0 0.098 12.4 0.0 1.8 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system PEPCK_ATP PF01293.20 KFY04585.1 - 3.4e-216 718.4 0.0 3.9e-216 718.2 0.0 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase MRFAP1 PF15155.6 KFY04585.1 - 0.052 14.1 0.0 0.09 13.3 0.0 1.3 1 0 0 1 1 1 0 MORF4 family-associated protein1 AAA_33 PF13671.6 KFY04585.1 - 0.17 12.0 0.0 0.31 11.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain DEAD PF00270.29 KFY04588.1 - 7e-48 162.7 0.0 1.3e-47 161.9 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KFY04588.1 - 3.6e-24 85.3 0.1 2.2e-23 82.7 0.0 2.5 3 0 0 3 3 3 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 KFY04588.1 - 4.6e-22 78.0 0.0 1.2e-21 76.7 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.15 KFY04588.1 - 1e-06 28.9 0.0 2.8e-06 27.5 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit CMS1 PF14617.6 KFY04588.1 - 0.71 9.2 0.0 0.71 9.2 0.0 3.5 4 1 0 4 4 4 0 U3-containing 90S pre-ribosomal complex subunit DEAD PF00270.29 KFY04589.1 - 1.2e-48 165.2 0.0 2.4e-48 164.2 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KFY04589.1 - 7e-24 84.3 0.0 2.2e-22 79.5 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DBP10CT PF08147.12 KFY04589.1 - 1.7e-22 79.4 3.6 5.4e-22 77.8 3.6 1.9 1 0 0 1 1 1 1 DBP10CT (NUC160) domain ResIII PF04851.15 KFY04589.1 - 1.5e-06 28.3 0.0 3.6e-06 27.1 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Zn_clus PF00172.18 KFY04592.1 - 4.1e-06 26.8 8.8 4.1e-06 26.8 8.8 1.6 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain FYTT PF07078.11 KFY04592.1 - 0.013 14.9 0.6 0.02 14.2 0.6 1.2 1 0 0 1 1 1 0 Forty-two-three protein Ank_4 PF13637.6 KFY04595.1 - 1.8e-10 41.2 0.0 0.00067 20.2 0.0 2.5 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 KFY04595.1 - 8.6e-10 39.1 0.0 6e-06 26.8 0.0 3.3 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KFY04595.1 - 3.9e-07 30.2 0.0 0.00022 21.5 0.0 2.6 1 1 0 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFY04595.1 - 3.5e-06 26.9 0.0 0.64 10.8 0.0 3.8 4 1 0 4 4 4 2 Ankyrin repeat Ig_Tie2_1 PF10430.9 KFY04595.1 - 0.0022 18.4 0.0 2.5 8.6 0.0 2.5 2 0 0 2 2 2 2 Tie-2 Ig-like domain 1 Ank PF00023.30 KFY04595.1 - 0.0046 17.4 0.0 19 5.9 0.0 3.7 4 0 0 4 4 4 2 Ankyrin repeat ATPase PF06745.13 KFY04595.1 - 0.014 14.8 0.0 2.4 7.4 0.0 2.2 2 0 0 2 2 2 0 KaiC Tricorn_C1 PF14684.6 KFY04595.1 - 0.06 13.4 0.1 9.8 6.3 0.0 2.2 2 0 0 2 2 2 0 Tricorn protease C1 domain OrfA PF17495.2 KFY04595.1 - 0.17 12.1 0.0 13 6.0 0.0 2.3 2 0 0 2 2 2 0 Vpr-like OrfA PRKG1_interact PF15898.5 KFY04596.1 - 0.002 19.0 5.5 0.16 12.9 5.2 2.5 1 1 0 1 1 1 1 cGMP-dependent protein kinase interacting domain WD40_alt PF14077.6 KFY04596.1 - 0.12 12.3 0.3 0.26 11.2 0.3 1.5 1 0 0 1 1 1 0 Alternative WD40 repeat motif Sacchrp_dh_NADP PF03435.18 KFY04596.1 - 0.15 12.3 0.0 0.34 11.2 0.0 1.5 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain WT1 PF02165.15 KFY04597.1 - 0.0035 16.6 0.3 0.0088 15.3 0.3 1.6 1 0 0 1 1 1 1 Wilm's tumour protein K_channel_TID PF07941.11 KFY04597.1 - 1.3 9.6 9.6 0.08 13.4 4.4 1.6 2 0 0 2 2 2 0 Potassium channel Kv1.4 tandem inactivation domain Zn_clus PF00172.18 KFY04602.1 - 0.0005 20.1 13.1 0.0011 19.1 13.1 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CHZ PF09649.10 KFY04602.1 - 0.0079 15.6 0.0 0.0079 15.6 0.0 3.0 3 0 0 3 3 3 1 Histone chaperone domain CHZ Ribosomal_S7e PF01251.18 KFY04607.1 - 6.2e-37 127.1 0.0 7e-37 127.0 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S7e Abhydrolase_1 PF00561.20 KFY04610.1 - 1.7e-15 57.4 0.0 3e-13 50.0 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KFY04610.1 - 3.9e-08 32.9 0.0 3.9e-07 29.6 0.0 1.9 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KFY04610.1 - 7.7e-08 33.2 0.0 9.9e-08 32.8 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Ndr PF03096.14 KFY04610.1 - 0.0012 17.6 0.0 0.004 15.9 0.0 2.0 1 1 0 1 1 1 1 Ndr family DLH PF01738.18 KFY04610.1 - 0.056 13.0 0.0 0.15 11.6 0.0 1.6 2 0 0 2 2 2 0 Dienelactone hydrolase family Caps_synth PF05704.12 KFY04611.1 - 3.7e-12 46.2 0.0 7.2e-12 45.3 0.0 1.4 1 0 0 1 1 1 1 Capsular polysaccharide synthesis protein Gly_transf_sug PF04488.15 KFY04611.1 - 4.2e-05 24.1 0.0 7.5e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif NmrA PF05368.13 KFY04612.1 - 2e-24 86.5 0.0 2.8e-24 86.0 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KFY04612.1 - 2e-05 24.6 0.0 2.9e-05 24.0 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding DUF4327 PF14217.6 KFY04612.1 - 0.15 12.2 0.0 0.27 11.4 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4327) Defensin_beta PF00711.19 KFY04613.1 - 0.24 11.5 3.1 0.21 11.7 1.2 2.0 2 0 0 2 2 2 0 Beta defensin tRNA-synt_1c PF00749.21 KFY04614.1 - 5.9e-70 235.6 0.0 5e-42 143.9 0.0 2.1 1 1 1 2 2 2 2 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.18 KFY04614.1 - 3.6e-27 95.4 0.0 9.3e-27 94.0 0.0 1.7 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain HTH_Tnp_Tc3_1 PF11427.8 KFY04614.1 - 0.13 12.2 0.0 0.28 11.1 0.0 1.5 1 0 0 1 1 1 0 Tc3 transposase LacAB_rpiB PF02502.18 KFY04618.1 - 3e-45 153.6 0.1 3.4e-45 153.4 0.1 1.0 1 0 0 1 1 1 1 Ribose/Galactose Isomerase Gly_rich_SFCGS PF14272.6 KFY04618.1 - 0.013 15.6 0.0 0.021 14.8 0.0 1.3 1 0 0 1 1 1 0 Glycine-rich SFCGS Fungal_trans PF04082.18 KFY04619.1 - 1.7e-27 96.1 0.0 1.5e-25 89.8 0.0 2.5 2 0 0 2 2 2 2 Fungal specific transcription factor domain tRNA-synt_2b PF00587.25 KFY04619.1 - 4.7e-14 52.7 0.0 2.5e-13 50.4 0.0 1.9 2 0 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.22 KFY04619.1 - 9.7e-10 38.6 0.5 3.6e-09 36.8 0.5 2.0 2 0 0 2 2 2 1 Seryl-tRNA synthetase N-terminal domain DIL PF01843.19 KFY04620.1 - 7.4e-33 112.9 0.6 1.5e-32 112.0 0.6 1.5 1 0 0 1 1 1 1 DIL domain Ank_2 PF12796.7 KFY04620.1 - 2.3e-11 44.1 0.0 9.6e-11 42.1 0.0 2.1 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KFY04620.1 - 1.4e-10 41.4 0.0 3.8e-06 27.3 0.0 3.6 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 KFY04620.1 - 3.3e-09 36.8 0.0 3.7e-05 23.9 0.0 2.6 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 KFY04620.1 - 5.3e-08 33.0 0.0 0.04 14.4 0.0 3.5 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.6 KFY04620.1 - 9.3e-06 25.6 0.0 0.64 10.8 0.0 3.9 3 0 0 3 3 3 1 Ankyrin repeat DUF4962 PF16332.5 KFY04620.1 - 0.014 14.0 0.1 0.022 13.3 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4962) COesterase PF00135.28 KFY04621.1 - 9.1e-72 242.6 0.0 1.6e-71 241.8 0.0 1.3 1 0 0 1 1 1 1 Carboxylesterase family Zn_clus PF00172.18 KFY04621.1 - 9.5e-09 35.2 9.3 1.5e-08 34.6 9.3 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Abhydrolase_3 PF07859.13 KFY04621.1 - 1.6e-06 28.2 0.4 2.5e-05 24.2 0.5 2.6 2 1 0 2 2 2 1 alpha/beta hydrolase fold Fungal_trans_2 PF11951.8 KFY04621.1 - 0.0095 14.8 0.0 0.014 14.2 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Say1_Mug180 PF10340.9 KFY04621.1 - 0.031 13.1 0.1 1.7 7.4 0.0 2.1 2 0 0 2 2 2 0 Steryl acetyl hydrolase Oxidored_FMN PF00724.20 KFY04622.1 - 5.6e-91 305.3 0.0 6.4e-91 305.1 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family HK_sensor PF16750.5 KFY04622.1 - 0.19 12.1 0.1 7.5 6.9 0.1 2.5 2 0 0 2 2 2 0 Sensor domain of 2-component histidine kinase Spc24 PF08286.11 KFY04624.1 - 0.16 12.2 0.5 2.2 8.6 0.1 2.5 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 DMPK_coil PF08826.10 KFY04624.1 - 0.72 10.0 6.1 0.28 11.3 1.3 2.6 3 0 0 3 3 3 0 DMPK coiled coil domain like ATG16 PF08614.11 KFY04624.1 - 1.9 8.7 8.4 1.1 9.4 1.1 2.9 3 0 0 3 3 3 0 Autophagy protein 16 (ATG16) M PF02370.16 KFY04624.1 - 3.1 8.7 8.7 0.12 13.0 1.7 2.6 2 0 0 2 2 2 0 M protein repeat Cytochrom_B561 PF03188.16 KFY04625.1 - 2.7e-15 56.7 6.6 5.3e-15 55.7 6.6 1.5 1 0 0 1 1 1 1 Eukaryotic cytochrome b561 DUF3425 PF11905.8 KFY04625.1 - 1.8e-11 44.1 2.2 6.8e-11 42.2 2.2 1.8 1 1 0 1 1 1 1 Domain of unknown function (DUF3425) bZIP_1 PF00170.21 KFY04625.1 - 0.0041 17.2 5.5 0.0076 16.3 5.5 1.3 1 0 0 1 1 1 1 bZIP transcription factor DUF418 PF04235.12 KFY04625.1 - 0.2 11.6 8.7 0.074 13.0 4.5 2.3 1 1 1 3 3 3 0 Protein of unknown function (DUF418) Ni_hydr_CYTB PF01292.20 KFY04625.1 - 0.42 10.2 10.4 7.4 6.1 10.4 2.3 1 1 0 1 1 1 0 Prokaryotic cytochrome b561 DUF4079 PF13301.6 KFY04625.1 - 1.5 9.0 13.2 0.98 9.6 8.1 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF4079) DUF4267 PF14087.6 KFY04626.1 - 2.9e-05 24.1 4.5 5e-05 23.3 4.5 1.5 1 1 0 1 1 1 1 Domain of unknown function (DUF4267) Dynamin_N PF00350.23 KFY04629.1 - 1.8e-34 119.2 0.1 3.7e-34 118.2 0.1 1.6 1 0 0 1 1 1 1 Dynamin family Dynamin_M PF01031.20 KFY04629.1 - 2.4e-20 72.9 0.0 1.5e-17 63.7 0.0 2.5 2 0 0 2 2 2 2 Dynamin central region MMR_HSR1 PF01926.23 KFY04629.1 - 1.4e-05 25.1 1.2 0.00011 22.3 0.4 2.7 2 1 0 2 2 2 1 50S ribosome-binding GTPase Trigger_C PF05698.14 KFY04629.1 - 0.011 15.7 3.2 0.011 15.7 1.1 2.1 2 0 0 2 2 2 0 Bacterial trigger factor protein (TF) C-terminus FeoB_N PF02421.18 KFY04629.1 - 0.022 14.3 0.1 6.6 6.2 0.1 2.5 2 0 0 2 2 2 0 Ferrous iron transport protein B AAA_16 PF13191.6 KFY04629.1 - 0.14 12.5 2.1 1.3 9.4 0.0 3.0 3 1 0 3 3 3 0 AAA ATPase domain HflK_N PF12221.8 KFY04629.1 - 0.31 11.1 0.8 10 6.2 0.0 3.0 3 0 0 3 3 3 0 Bacterial membrane protein N terminal Sugar_tr PF00083.24 KFY04630.1 - 2.1e-96 323.6 22.7 1.2e-65 222.2 10.2 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 KFY04630.1 - 1.6e-17 63.5 32.1 4e-10 39.1 6.6 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily CytB6-F_Fe-S PF08802.10 KFY04630.1 - 7.2 6.7 6.5 31 4.7 1.7 3.1 2 0 0 2 2 2 0 Cytochrome B6-F complex Fe-S subunit Dak2 PF02734.17 KFY04631.1 - 1.3e-37 129.4 1.2 3e-37 128.2 0.0 2.1 3 0 0 3 3 3 1 DAK2 domain DUF1541 PF07563.11 KFY04631.1 - 0.12 12.3 0.0 0.24 11.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1541) Dak1 PF02733.17 KFY04632.1 - 1.3e-86 290.3 0.0 1.5e-86 290.2 0.0 1.0 1 0 0 1 1 1 1 Dak1 domain adh_short_C2 PF13561.6 KFY04633.1 - 1.1e-54 185.5 0.2 1.4e-54 185.1 0.2 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KFY04633.1 - 2.4e-45 154.4 0.4 3.6e-45 153.8 0.4 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 KFY04633.1 - 2e-11 44.1 0.2 2.8e-11 43.7 0.2 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 KFY04633.1 - 0.0011 18.5 0.0 0.0013 18.3 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 KFY04633.1 - 0.1 12.0 0.0 1.7 8.0 0.0 2.0 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase rve PF00665.26 KFY04635.1 - 2.4e-07 31.0 0.0 8.2e-07 29.2 0.0 1.9 2 0 0 2 2 2 1 Integrase core domain UCH_N PF16674.5 KFY04635.1 - 0.0026 17.7 0.0 3 7.8 0.0 2.2 1 1 1 2 2 2 2 N-terminal of ubiquitin carboxyl-terminal hydrolase 37 rve_3 PF13683.6 KFY04635.1 - 0.016 15.0 0.0 0.037 13.8 0.0 1.7 1 0 0 1 1 1 0 Integrase core domain HTH_Tnp_1 PF01527.20 KFY04635.1 - 0.063 13.6 0.1 18 5.8 0.0 2.5 2 0 0 2 2 2 0 Transposase Trypan_PARP PF05887.11 KFY04635.1 - 0.13 12.3 20.5 9.7 6.2 20.5 2.3 1 1 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) NESP55 PF06390.12 KFY04635.1 - 0.15 11.6 5.0 0.25 10.9 5.0 1.3 1 0 0 1 1 1 0 Neuroendocrine-specific golgi protein P55 (NESP55) Abhydrolase_1 PF00561.20 KFY04636.1 - 4.5e-28 98.6 0.7 1.9e-18 67.0 0.2 2.2 1 1 0 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KFY04636.1 - 4.2e-26 91.7 0.2 5.5e-16 58.6 0.1 2.1 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KFY04636.1 - 8.4e-18 65.8 0.0 1.2e-17 65.3 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 KFY04636.1 - 6.6e-08 32.3 1.2 0.00065 19.2 0.0 2.6 2 1 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_5 PF12695.7 KFY04636.1 - 9.7e-05 22.2 0.0 0.17 11.6 0.0 2.2 2 0 0 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_2 PF02230.16 KFY04636.1 - 0.0012 18.7 0.0 0.0025 17.7 0.0 1.5 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase DLH PF01738.18 KFY04636.1 - 0.0043 16.6 0.0 0.0083 15.7 0.0 1.4 1 0 0 1 1 1 1 Dienelactone hydrolase family DUF915 PF06028.11 KFY04636.1 - 0.0053 16.1 0.0 0.012 15.0 0.0 1.5 2 0 0 2 2 2 1 Alpha/beta hydrolase of unknown function (DUF915) Ser_hydrolase PF06821.13 KFY04636.1 - 0.0086 15.9 0.0 0.23 11.3 0.0 2.4 2 0 0 2 2 2 1 Serine hydrolase Abhydrolase_4 PF08386.10 KFY04636.1 - 0.045 13.9 0.0 0.16 12.1 0.0 2.0 2 0 0 2 2 2 0 TAP-like protein FSH1 PF03959.13 KFY04636.1 - 0.12 12.0 0.2 0.73 9.5 0.0 2.1 1 1 1 2 2 2 0 Serine hydrolase (FSH1) UPF0227 PF05728.12 KFY04636.1 - 0.15 12.0 0.0 1.3 9.0 0.0 2.0 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0227) Chlorophyllase2 PF12740.7 KFY04636.1 - 0.16 10.9 0.0 0.3 10.0 0.0 1.4 1 1 0 1 1 1 0 Chlorophyllase enzyme MFS_1 PF07690.16 KFY04639.1 - 1.7e-21 76.6 41.4 1.5e-20 73.4 41.9 1.9 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KFY04639.1 - 5.4e-12 45.3 8.9 5.4e-12 45.3 8.9 1.9 2 1 0 2 2 2 1 Sugar (and other) transporter LapA_dom PF06305.11 KFY04639.1 - 0.022 14.6 3.1 6.7 6.6 0.2 3.6 3 0 0 3 3 3 0 Lipopolysaccharide assembly protein A domain DUF1449 PF07290.11 KFY04639.1 - 0.21 11.2 1.8 0.5 9.9 1.8 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1449) Beta_elim_lyase PF01212.21 KFY04640.1 - 3.3e-62 210.4 0.0 4.5e-62 210.0 0.0 1.1 1 0 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.17 KFY04640.1 - 0.031 13.6 0.0 0.055 12.8 0.0 1.3 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family p450 PF00067.22 KFY04642.1 - 4.7e-61 207.0 0.0 6.6e-61 206.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 adh_short PF00106.25 KFY04642.1 - 3.8e-13 49.3 0.0 7.6e-13 48.4 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 KFY04642.1 - 2.5e-09 37.1 0.0 4.7e-09 36.1 0.0 1.4 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KFY04642.1 - 2.6e-07 30.7 0.1 7.2e-07 29.3 0.1 1.7 1 0 0 1 1 1 1 KR domain Sacchrp_dh_NADP PF03435.18 KFY04642.1 - 0.0039 17.5 0.1 0.0083 16.4 0.1 1.6 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Aminotran_1_2 PF00155.21 KFY04643.1 - 1e-43 149.9 0.0 1.3e-43 149.6 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II BNR_2 PF13088.6 KFY04645.1 - 0.00079 18.8 0.0 0.002 17.5 0.0 1.7 1 1 0 1 1 1 1 BNR repeat-like domain BNR PF02012.20 KFY04645.1 - 0.0012 18.6 5.8 1.3 9.3 0.0 4.1 3 0 0 3 3 3 2 BNR/Asp-box repeat Sortilin-Vps10 PF15902.5 KFY04645.1 - 0.22 10.3 0.9 15 4.3 0.1 2.4 2 1 0 3 3 3 0 Sortilin, neurotensin receptor 3, Sua5_yciO_yrdC PF01300.18 KFY04646.1 - 8.8e-54 181.7 0.0 1.2e-53 181.3 0.0 1.2 1 0 0 1 1 1 1 Telomere recombination SUA5 PF03481.13 KFY04646.1 - 2.4e-28 99.4 0.0 4.4e-28 98.5 0.0 1.5 1 0 0 1 1 1 1 Putative GTP-binding controlling metal-binding Clat_adaptor_s PF01217.20 KFY04647.1 - 1.5e-14 54.1 0.2 1.5e-13 50.9 0.4 1.9 2 0 0 2 2 2 1 Clathrin adaptor complex small chain MCM PF00493.23 KFY04648.1 - 2.4e-101 337.5 0.0 3.5e-101 337.0 0.0 1.2 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 KFY04648.1 - 1.7e-39 134.5 1.0 3.3e-39 133.6 1.0 1.4 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 KFY04648.1 - 1.3e-29 102.5 3.7 2.9e-29 101.3 3.7 1.6 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 KFY04648.1 - 9.6e-20 71.1 0.0 3.2e-19 69.4 0.0 2.0 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 KFY04648.1 - 3e-06 26.8 0.0 0.00016 21.1 0.0 2.4 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 KFY04648.1 - 2.7e-05 24.2 0.1 0.00011 22.2 0.0 2.1 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 KFY04648.1 - 0.00029 20.7 0.0 0.0011 18.8 0.0 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 KFY04648.1 - 0.11 12.1 0.2 2.4 7.8 0.0 2.7 3 0 0 3 3 3 0 Sigma-54 interaction domain Zn-ribbon_8 PF09723.10 KFY04648.1 - 0.13 12.4 1.5 0.31 11.2 1.5 1.6 1 0 0 1 1 1 0 Zinc ribbon domain AAA_16 PF13191.6 KFY04648.1 - 0.57 10.6 2.5 8.6 6.7 2.5 3.0 1 1 0 1 1 1 0 AAA ATPase domain Mg_chelatase_C PF13335.6 KFY04648.1 - 1.5 9.5 6.9 0.66 10.7 1.8 2.9 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI C-terminal Rad21_Rec8_N PF04825.13 KFY04650.1 - 1.1e-36 125.3 0.0 2e-36 124.5 0.0 1.4 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein Rad21_Rec8 PF04824.16 KFY04650.1 - 7.8e-09 34.7 0.2 2.3e-08 33.2 0.2 1.8 1 0 0 1 1 1 1 Conserved region of Rad21 / Rec8 like protein E1-E2_ATPase PF00122.20 KFY04651.1 - 7.2e-48 162.5 1.6 4.4e-47 159.9 0.1 2.4 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 KFY04651.1 - 6.1e-41 140.1 2.9 6.1e-41 140.1 2.9 2.0 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 KFY04651.1 - 2.3e-19 70.5 1.8 7.5e-18 65.6 1.8 3.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 KFY04651.1 - 2.4e-18 65.6 0.0 4.9e-18 64.6 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Cation_ATPase PF13246.6 KFY04651.1 - 4.3e-11 42.7 0.0 9.7e-11 41.6 0.0 1.6 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 KFY04651.1 - 0.00047 20.0 0.7 0.00047 20.0 0.7 1.8 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase LptF_LptG PF03739.14 KFY04651.1 - 0.0013 17.7 0.3 0.12 11.2 0.0 2.3 2 0 0 2 2 2 2 Lipopolysaccharide export system permease LptF/LptG zf-HC5HC2H_2 PF13832.6 KFY04654.1 - 7.7e-19 67.9 1.2 7.7e-19 67.9 1.2 4.2 4 0 0 4 4 4 3 PHD-zinc-finger like domain BAH PF01426.18 KFY04654.1 - 5.2e-14 52.2 0.1 9.9e-14 51.2 0.1 1.5 1 0 0 1 1 1 1 BAH domain zf-HC5HC2H PF13771.6 KFY04654.1 - 6.5e-14 52.0 3.8 6.5e-14 52.0 3.8 4.7 4 1 0 4 4 4 2 PHD-like zinc-binding domain PHD PF00628.29 KFY04654.1 - 2.2e-11 43.5 54.4 2.1e-06 27.5 6.9 6.2 6 0 0 6 6 6 3 PHD-finger PHD_2 PF13831.6 KFY04654.1 - 7.8e-09 35.0 3.7 7.8e-09 35.0 3.7 5.2 6 0 0 6 6 6 1 PHD-finger WD40 PF00400.32 KFY04655.1 - 8.9e-19 67.5 0.0 3.4e-08 34.0 0.0 3.0 3 0 0 3 3 3 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 KFY04655.1 - 7.1e-09 35.9 0.0 0.00018 21.8 0.0 2.5 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 KFY04655.1 - 0.00013 20.8 0.1 0.094 11.3 0.0 2.1 1 1 1 2 2 2 2 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 KFY04655.1 - 0.00018 20.6 0.0 0.0058 15.6 0.0 2.1 1 1 1 2 2 2 1 WD40 region of Ge1, enhancer of mRNA-decapping protein PQQ_2 PF13360.6 KFY04655.1 - 0.093 12.3 0.3 0.5 9.9 0.3 1.9 1 1 0 1 1 1 0 PQQ-like domain Nbas_N PF15492.6 KFY04655.1 - 0.13 11.5 0.0 8 5.7 0.0 2.1 1 1 1 2 2 2 0 Neuroblastoma-amplified sequence, N terminal Sel1 PF08238.12 KFY04657.1 - 1.1e-11 45.0 7.2 0.0013 19.4 0.0 3.7 3 0 0 3 3 3 3 Sel1 repeat COPIIcoated_ERV PF07970.12 KFY04658.1 - 1.7e-84 283.1 0.0 2.9e-84 282.4 0.0 1.4 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.6 KFY04658.1 - 1.7e-28 98.8 0.1 1.3e-27 96.0 0.0 2.1 2 0 0 2 2 2 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) Sulfate_transp PF00916.20 KFY04659.1 - 5.3e-105 351.3 23.6 7e-105 350.9 23.6 1.2 1 0 0 1 1 1 1 Sulfate permease family STAS PF01740.21 KFY04659.1 - 2.2e-09 36.9 0.0 4.4e-09 36.0 0.0 1.4 1 0 0 1 1 1 1 STAS domain MFS_MOT1 PF16983.5 KFY04659.1 - 0.013 15.9 2.5 0.013 15.9 2.5 3.4 3 1 0 3 3 3 0 Molybdate transporter of MFS superfamily VRR_NUC PF08774.11 KFY04660.1 - 5.8e-26 90.7 0.0 1.2e-25 89.7 0.0 1.5 1 0 0 1 1 1 1 VRR-NUC domain Dpy-30 PF05186.13 KFY04661.1 - 7.5e-15 54.4 0.0 1.1e-14 53.8 0.0 1.2 1 0 0 1 1 1 1 Dpy-30 motif Ribosomal_S13_N PF08069.12 KFY04662.1 - 3e-30 104.0 0.0 5.1e-30 103.3 0.0 1.4 1 0 0 1 1 1 1 Ribosomal S13/S15 N-terminal domain Ribosomal_S15 PF00312.22 KFY04662.1 - 4.7e-15 55.5 0.2 7e-15 55.0 0.2 1.2 1 0 0 1 1 1 1 Ribosomal protein S15 PAX PF00292.18 KFY04662.1 - 0.03 14.3 0.1 0.072 13.0 0.0 1.7 2 0 0 2 2 2 0 'Paired box' domain HOIP-UBA PF16678.5 KFY04662.1 - 0.12 12.4 0.0 0.25 11.4 0.0 1.4 1 1 0 1 1 1 0 HOIP UBA domain pair RabGAP-TBC PF00566.18 KFY04663.1 - 8.6e-31 107.3 0.0 9.5e-26 90.8 0.0 2.2 2 0 0 2 2 2 2 Rab-GTPase-TBC domain DUF4072 PF13284.6 KFY04663.1 - 0.085 13.3 2.2 0.87 10.1 0.1 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4072) 7tm_2 PF00002.24 KFY04664.1 - 1e-06 28.2 17.0 1e-06 28.2 17.0 2.0 1 1 1 2 2 2 1 7 transmembrane receptor (Secretin family) OGG_N PF07934.12 KFY04665.1 - 1e-35 122.4 0.0 2.1e-35 121.4 0.0 1.5 1 0 0 1 1 1 1 8-oxoguanine DNA glycosylase, N-terminal domain HhH-GPD PF00730.25 KFY04665.1 - 4.9e-16 59.1 0.0 8.1e-16 58.4 0.0 1.3 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.23 KFY04665.1 - 9.9e-05 22.0 0.0 0.00031 20.5 0.0 1.9 1 0 0 1 1 1 1 Helix-hairpin-helix motif SIR2 PF02146.17 KFY04667.1 - 7.2e-29 101.0 0.0 1.2e-09 38.3 0.0 3.2 2 1 0 3 3 3 3 Sir2 family Beta-lactamase PF00144.24 KFY04669.1 - 7.4e-27 94.5 1.1 1.7e-26 93.2 1.1 1.5 1 1 0 1 1 1 1 Beta-lactamase MFS_1 PF07690.16 KFY04671.1 - 1.5e-53 182.0 16.4 1.5e-53 182.0 16.4 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KFY04671.1 - 9.2e-08 31.4 10.0 9.2e-08 31.4 10.0 3.1 2 1 1 3 3 3 1 Sugar (and other) transporter MFS_5 PF05631.14 KFY04671.1 - 0.00024 20.2 1.4 0.00024 20.2 1.4 1.9 2 0 0 2 2 2 1 Sugar-tranasporters, 12 TM TRI12 PF06609.13 KFY04671.1 - 0.00047 18.7 5.1 0.00092 17.7 5.1 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF4630 PF15443.6 KFY04671.1 - 0.2 11.8 0.5 0.69 10.1 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4630) LapA_dom PF06305.11 KFY04671.1 - 0.22 11.3 6.1 5 7.0 0.8 3.2 3 0 0 3 3 3 0 Lipopolysaccharide assembly protein A domain OATP PF03137.20 KFY04671.1 - 5.4 5.2 10.7 0.14 10.4 4.0 1.8 2 1 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family TPR_11 PF13414.6 KFY04672.1 - 5.5e-06 26.0 0.1 0.0022 17.6 0.0 3.0 1 1 1 2 2 2 2 TPR repeat TPR_2 PF07719.17 KFY04672.1 - 4.6e-05 23.2 9.9 0.016 15.3 0.0 4.9 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_14 PF13428.6 KFY04672.1 - 0.0003 21.4 2.4 10 7.3 0.0 5.1 4 1 0 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.6 KFY04672.1 - 0.001 19.3 3.2 0.0052 17.0 0.2 3.5 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.28 KFY04672.1 - 0.0012 18.6 0.2 3.2 7.7 0.1 4.2 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.6 KFY04672.1 - 0.025 15.2 0.4 1.8 9.3 0.1 3.4 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_8 PF13181.6 KFY04672.1 - 0.027 14.7 1.4 67 4.1 0.1 4.5 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_19 PF14559.6 KFY04672.1 - 0.075 13.6 4.7 1.7 9.2 0.1 4.5 4 2 2 6 6 6 0 Tetratricopeptide repeat TPR_17 PF13431.6 KFY04672.1 - 0.12 12.8 1.2 5.4 7.6 0.0 4.0 6 0 0 6 6 6 0 Tetratricopeptide repeat Aminotran_1_2 PF00155.21 KFY04674.1 - 9.7e-85 284.9 0.0 1.8e-84 284.0 0.0 1.5 1 0 0 1 1 1 1 Aminotransferase class I and II Syntaxin-18_N PF10496.9 KFY04674.1 - 1.9e-11 44.1 0.2 2.6e-10 40.4 0.0 2.8 2 1 0 2 2 2 1 SNARE-complex protein Syntaxin-18 N-terminus DprA_WH PF17782.1 KFY04674.1 - 0.015 15.4 0.0 0.057 13.5 0.0 2.0 1 0 0 1 1 1 0 DprA winged helix domain DUF1233 PF06806.12 KFY04674.1 - 0.14 11.8 0.0 0.69 9.6 0.0 2.2 2 0 0 2 2 2 0 Putative excisionase (DUF1233) BLOC1_2 PF10046.9 KFY04674.1 - 0.73 10.2 8.7 0.4 11.0 4.4 2.7 3 0 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF16 PF01519.16 KFY04674.1 - 4.4 7.9 8.5 14 6.2 3.5 2.6 2 0 0 2 2 2 0 Protein of unknown function DUF16 DUF5353 PF17304.2 KFY04677.1 - 1.1e-35 121.2 3.5 3.1e-35 119.7 3.5 1.8 1 0 0 1 1 1 1 Family of unknown function (DUF5353) DUF883 PF05957.13 KFY04677.1 - 0.02 15.5 1.9 0.02 15.5 1.9 2.2 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF883) ETRAMP PF09716.10 KFY04677.1 - 0.12 12.4 5.6 0.4 10.8 5.6 2.1 1 1 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) RAP1 PF07218.11 KFY04677.1 - 0.48 8.6 6.7 0.58 8.4 6.7 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) V-SNARE_C PF12352.8 KFY04678.1 - 1.5e-14 54.0 0.1 3.4e-14 52.9 0.1 1.7 1 0 0 1 1 1 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.13 KFY04678.1 - 0.0001 22.1 0.5 0.0021 18.0 0.0 2.4 2 0 0 2 2 2 1 Sec20 Baculo_PEP_C PF04513.12 KFY04678.1 - 0.056 13.5 2.9 0.13 12.3 2.3 1.7 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Snapin_Pallidin PF14712.6 KFY04678.1 - 0.19 12.2 1.0 1.4 9.4 0.1 2.4 3 0 0 3 3 3 0 Snapin/Pallidin KxDL PF10241.9 KFY04678.1 - 0.35 11.2 4.0 11 6.3 1.4 3.2 2 1 0 2 2 2 0 Uncharacterized conserved protein TPK_catalytic PF04263.16 KFY04679.1 - 2.9e-26 91.8 0.0 3.9e-26 91.5 0.0 1.2 1 0 0 1 1 1 1 Thiamin pyrophosphokinase, catalytic domain TPK_B1_binding PF04265.14 KFY04679.1 - 2.1e-21 75.4 0.0 3.2e-21 74.8 0.0 1.3 1 0 0 1 1 1 1 Thiamin pyrophosphokinase, vitamin B1 binding domain E1-E2_ATPase PF00122.20 KFY04680.1 - 5e-18 65.2 0.0 1.1e-17 64.1 0.0 1.6 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.26 KFY04680.1 - 2.9e-14 53.9 1.6 7.7e-08 32.9 1.7 3.1 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 KFY04680.1 - 9.5e-05 22.4 0.0 0.0012 18.9 0.0 2.5 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 KFY04680.1 - 0.0085 15.9 0.0 0.045 13.5 0.0 2.1 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DUF4139 PF13598.6 KFY04681.1 - 8.7e-33 113.8 0.0 3.7e-31 108.5 0.0 2.9 2 1 0 2 2 2 1 Domain of unknown function (DUF4139) DUF4140 PF13600.6 KFY04681.1 - 1.5e-21 76.6 0.1 1.5e-21 76.6 0.1 3.2 2 1 0 2 2 2 1 N-terminal domain of unknown function (DUF4140) DUF4337 PF14235.6 KFY04681.1 - 0.73 9.9 4.7 1.7 8.8 4.7 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) 2-oxoacid_dh PF00198.23 KFY04682.1 - 1.9e-74 250.0 0.0 2.4e-74 249.7 0.0 1.1 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 KFY04682.1 - 2.3e-17 62.6 3.8 3.1e-17 62.1 1.1 2.3 2 0 0 2 2 2 1 Biotin-requiring enzyme E3_binding PF02817.17 KFY04682.1 - 3.7e-13 49.6 0.3 9.1e-13 48.3 0.3 1.7 1 0 0 1 1 1 1 e3 binding domain DUF3614 PF12267.8 KFY04682.1 - 0.051 14.1 0.1 0.24 11.9 0.0 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF3614) Sec7 PF01369.20 KFY04683.1 - 8.1e-71 237.5 0.3 8.1e-71 237.5 0.3 3.1 3 1 1 4 4 4 1 Sec7 domain Sec7_N PF12783.7 KFY04683.1 - 1.8e-40 138.4 4.0 1.8e-40 138.4 4.0 2.7 2 0 0 2 2 2 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF1981 PF09324.10 KFY04683.1 - 2.3e-31 107.5 7.8 2e-30 104.5 0.1 4.9 5 0 0 5 5 5 1 Domain of unknown function (DUF1981) DCB PF16213.5 KFY04683.1 - 1.4e-19 70.4 0.5 1.4e-19 70.4 0.5 3.5 4 0 0 4 4 4 1 Dimerisation and cyclophilin-binding domain of Mon2 NAD_binding_7 PF13241.6 KFY04684.1 - 2.4e-32 111.4 0.1 3.6e-32 110.9 0.1 1.3 1 0 0 1 1 1 1 Putative NAD(P)-binding Sirohm_synth_C PF14823.6 KFY04684.1 - 1.8e-25 88.4 0.0 2.7e-25 87.8 0.0 1.3 1 0 0 1 1 1 1 Sirohaem biosynthesis protein C-terminal Sirohm_synth_M PF14824.6 KFY04684.1 - 9.8e-14 50.5 0.0 1.9e-13 49.6 0.0 1.5 1 0 0 1 1 1 1 Sirohaem biosynthesis protein central Pyr_redox_3 PF13738.6 KFY04684.1 - 0.00056 19.3 0.0 0.00075 18.8 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.20 KFY04684.1 - 0.0062 16.6 0.0 0.0098 16.0 0.0 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase AlaDh_PNT_C PF01262.21 KFY04684.1 - 0.065 12.5 0.0 0.09 12.1 0.0 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Semialdhyde_dh PF01118.24 KFY04684.1 - 0.094 13.2 0.0 0.16 12.4 0.0 1.4 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain ThiF PF00899.21 KFY04684.1 - 0.21 10.9 0.5 1.4 8.2 0.0 2.0 1 1 1 2 2 2 0 ThiF family FYVE PF01363.21 KFY04685.1 - 6.2e-21 74.3 29.9 4.1e-16 58.9 8.3 2.9 3 0 0 3 3 3 2 FYVE zinc finger Rbsn PF11464.8 KFY04685.1 - 2.5e-19 68.7 1.5 5.4e-19 67.6 1.5 1.6 1 0 0 1 1 1 1 Rabenosyn Rab binding domain zf-AN1 PF01428.16 KFY04685.1 - 8.4e-05 22.7 2.5 8.4e-05 22.7 2.5 4.3 5 1 1 6 6 4 1 AN1-like Zinc finger zf-Di19 PF05605.12 KFY04685.1 - 0.00021 21.5 5.5 0.027 14.8 0.1 2.8 2 0 0 2 2 2 2 Drought induced 19 protein (Di19), zinc-binding YqaH PF17448.2 KFY04685.1 - 0.058 13.7 0.9 0.2 12.0 0.7 2.0 2 0 0 2 2 2 0 Uncharacterized YqaH-like ABC_tran_CTD PF16326.5 KFY04685.1 - 0.2 11.9 5.8 9.5 6.6 0.0 2.7 2 0 0 2 2 2 0 ABC transporter C-terminal domain Flagellin_N PF00669.20 KFY04685.1 - 0.24 11.5 1.9 22 5.1 0.0 3.0 3 0 0 3 3 3 0 Bacterial flagellin N-terminal helical region zf-C2H2_2 PF12756.7 KFY04685.1 - 0.27 11.6 11.7 0.76 10.1 0.0 3.7 3 0 0 3 3 3 0 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.6 KFY04685.1 - 0.66 11.0 0.0 0.66 11.0 0.0 6.4 5 1 1 6 6 6 0 C2H2-type zinc finger UBZ_FAAP20 PF15750.5 KFY04685.1 - 0.79 9.7 3.1 6 6.9 0.4 3.0 2 0 0 2 2 2 0 Ubiquitin-binding zinc-finger zf-WRNIP1_ubi PF18279.1 KFY04685.1 - 0.83 10.4 3.5 31 5.5 0.1 2.9 2 0 0 2 2 2 0 Werner helicase-interacting protein 1 ubiquitin-binding domain Peroxin-13_N PF04088.13 KFY04687.1 - 3.7e-42 144.0 0.7 4.7e-42 143.7 0.7 1.1 1 0 0 1 1 1 1 Peroxin 13, N-terminal region GST_N PF02798.20 KFY04688.1 - 3.2e-10 40.2 0.0 5.8e-10 39.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 KFY04688.1 - 4.3e-08 33.5 0.0 8.5e-08 32.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 KFY04688.1 - 1.4e-07 31.7 0.0 2.8e-07 30.7 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 KFY04688.1 - 6.5e-07 29.5 0.0 9.8e-07 28.9 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Glutaredoxin PF00462.24 KFY04688.1 - 0.00018 21.6 0.3 0.0012 19.0 0.0 2.4 3 0 0 3 3 3 1 Glutaredoxin GST_C_2 PF13410.6 KFY04688.1 - 0.0039 17.2 0.0 0.008 16.2 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 KFY04688.1 - 0.0085 16.3 0.1 0.017 15.3 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain COesterase PF00135.28 KFY04689.1 - 1.6e-86 291.2 0.0 2.1e-86 290.8 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Acetyltransf_3 PF13302.7 KFY04689.1 - 2.7e-30 105.8 0.1 5.7e-30 104.8 0.1 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KFY04689.1 - 3.8e-05 23.9 0.0 0.00012 22.3 0.0 1.9 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_8 PF13523.6 KFY04689.1 - 5.2e-05 23.0 0.1 0.00011 22.0 0.1 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 KFY04689.1 - 0.026 14.5 0.0 0.071 13.1 0.0 1.7 1 0 0 1 1 1 0 FR47-like protein Abhydrolase_3 PF07859.13 KFY04689.1 - 0.039 13.8 0.0 0.1 12.5 0.0 1.7 1 1 0 1 1 1 0 alpha/beta hydrolase fold HMG-CoA_red PF00368.18 KFY04690.1 - 1.2e-140 468.7 4.5 1.7e-140 468.2 4.5 1.2 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A reductase HPIH PF13323.6 KFY04690.1 - 2.4e-48 163.9 0.0 4.3e-48 163.1 0.0 1.4 1 0 0 1 1 1 1 N-terminal domain with HPIH motif Sterol-sensing PF12349.8 KFY04690.1 - 1.7e-11 44.2 9.1 1.5e-10 41.1 9.1 2.2 1 1 0 1 1 1 1 Sterol-sensing domain of SREBP cleavage-activation Patched PF02460.18 KFY04690.1 - 2.5e-07 29.2 1.3 4e-07 28.5 1.3 1.3 1 0 0 1 1 1 1 Patched family SNARE PF05739.19 KFY04693.1 - 1.2e-11 44.4 0.1 2.7e-11 43.3 0.1 1.6 1 0 0 1 1 1 1 SNARE domain Syntaxin-5_N PF11416.8 KFY04693.1 - 6.2e-11 41.2 1.0 2.2e-10 39.4 1.0 2.1 1 0 0 1 1 1 1 Syntaxin-5 N-terminal, Sly1p-binding domain Syntaxin PF00804.25 KFY04693.1 - 0.00074 19.3 10.7 0.0061 16.2 0.3 3.2 2 1 1 3 3 3 1 Syntaxin Prominin PF05478.11 KFY04693.1 - 0.021 12.8 0.3 1.5 6.7 0.3 2.2 2 0 0 2 2 2 0 Prominin Syntaxin-18_N PF10496.9 KFY04693.1 - 0.022 15.0 2.5 0.022 15.0 0.2 2.2 3 0 0 3 3 3 0 SNARE-complex protein Syntaxin-18 N-terminus MCPsignal PF00015.21 KFY04693.1 - 0.029 14.2 7.9 0.98 9.2 0.2 2.7 3 0 0 3 3 3 0 Methyl-accepting chemotaxis protein (MCP) signalling domain KxDL PF10241.9 KFY04693.1 - 0.059 13.7 6.7 1.8 8.9 0.3 4.0 4 1 1 5 5 5 0 Uncharacterized conserved protein DUF4988 PF16378.5 KFY04693.1 - 0.13 11.9 2.6 5.5 6.6 0.4 2.8 2 1 1 3 3 3 0 Domain of unknown function NPV_P10 PF05531.12 KFY04693.1 - 0.21 12.1 8.0 5.4 7.6 0.1 3.8 3 1 1 4 4 4 0 Nucleopolyhedrovirus P10 protein TRPM_tetra PF16519.5 KFY04693.1 - 2.8 8.1 5.5 2 8.5 0.4 3.2 4 0 0 4 4 4 0 Tetramerisation domain of TRPM DUF948 PF06103.11 KFY04693.1 - 4.5 7.6 6.5 13 6.1 0.0 3.7 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) PRKG1_interact PF15898.5 KFY04693.1 - 7.8 7.5 9.5 5.7 7.9 0.6 2.7 2 1 1 3 3 3 0 cGMP-dependent protein kinase interacting domain DEAD PF00270.29 KFY04694.1 - 2.2e-41 141.5 0.0 3.5e-41 140.9 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 KFY04694.1 - 6.8e-25 87.6 0.0 6.4e-24 84.4 0.0 2.4 3 0 0 3 3 3 1 Helicase conserved C-terminal domain CMS1 PF14617.6 KFY04694.1 - 0.098 12.0 0.0 0.19 11.1 0.0 1.3 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit zn-ribbon_14 PF16503.5 KFY04698.1 - 1.2e-19 69.5 3.1 2e-19 68.8 3.1 1.4 1 0 0 1 1 1 1 Zinc-ribbon RecR PF02132.15 KFY04698.1 - 0.004 16.7 0.8 0.0077 15.8 0.8 1.4 1 0 0 1 1 1 1 RecR protein OCD_Mu_crystall PF02423.15 KFY04699.1 - 1.3e-08 34.2 0.4 3.5e-05 22.9 0.1 2.2 2 0 0 2 2 2 2 Ornithine cyclodeaminase/mu-crystallin family Shikimate_DH PF01488.20 KFY04699.1 - 0.0062 16.6 0.0 1.7 8.7 0.0 3.0 3 0 0 3 3 3 2 Shikimate / quinate 5-dehydrogenase Aldo_ket_red PF00248.21 KFY04700.1 - 1.2e-65 221.6 0.0 2.1e-65 220.8 0.0 1.3 1 0 0 1 1 1 1 Aldo/keto reductase family GMC_oxred_N PF00732.19 KFY04700.1 - 2.6e-55 187.9 0.0 3.7e-55 187.4 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KFY04700.1 - 1.6e-28 100.1 0.0 3.1e-28 99.1 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase Thi4 PF01946.17 KFY04700.1 - 1.9e-05 24.0 0.4 0.00025 20.4 0.1 2.2 2 0 0 2 2 2 1 Thi4 family NAD_binding_8 PF13450.6 KFY04700.1 - 0.00019 21.6 0.0 0.00063 19.9 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 KFY04700.1 - 0.0011 18.1 0.0 0.12 11.4 0.1 2.3 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.24 KFY04700.1 - 0.0028 17.3 0.4 0.018 14.6 0.1 2.4 3 0 0 3 3 3 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 KFY04700.1 - 0.0038 16.3 0.0 0.0061 15.6 0.0 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_2 PF07992.14 KFY04700.1 - 0.051 12.8 0.2 0.9 8.7 0.1 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KFY04700.1 - 0.11 11.2 0.0 0.17 10.5 0.0 1.2 1 0 0 1 1 1 0 HI0933-like protein Zn_clus PF00172.18 KFY04701.1 - 0.00016 21.7 10.8 0.00016 21.7 10.8 2.0 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DAO PF01266.24 KFY04702.1 - 6.2e-29 101.7 0.4 8.1e-29 101.3 0.4 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase ADH_zinc_N PF00107.26 KFY04702.1 - 6.3e-23 81.2 0.4 1.7e-22 79.8 0.4 1.8 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 KFY04702.1 - 3.6e-09 36.5 0.0 8.8e-09 35.2 0.0 1.7 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 KFY04702.1 - 2.9e-06 28.3 0.0 1.3e-05 26.2 0.0 2.1 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 KFY04702.1 - 0.0062 16.1 0.7 0.39 10.2 0.0 2.3 1 1 0 2 2 2 2 Glucose dehydrogenase C-terminus AlaDh_PNT_C PF01262.21 KFY04702.1 - 0.039 13.2 0.1 8.1 5.7 0.0 2.2 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain PTR2 PF00854.21 KFY04703.1 - 1.8e-44 152.2 4.2 3.2e-44 151.4 4.2 1.3 1 0 0 1 1 1 1 POT family NLPC_P60 PF00877.19 KFY04704.1 - 7.4e-22 77.4 0.1 1.7e-21 76.2 0.1 1.6 1 0 0 1 1 1 1 NlpC/P60 family SH3_16 PF18348.1 KFY04704.1 - 7e-06 25.8 0.3 0.0052 16.6 0.0 2.5 2 0 0 2 2 2 2 Bacterial dipeptidyl-peptidase Sh3 domain SH3_3 PF08239.11 KFY04704.1 - 0.00015 22.0 0.0 0.00059 20.1 0.0 2.1 1 0 0 1 1 1 1 Bacterial SH3 domain Abhydrolase_1 PF00561.20 KFY04705.1 - 2e-28 99.8 0.0 3.9e-28 98.8 0.0 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KFY04705.1 - 2.9e-10 39.8 0.0 1e-08 34.7 0.0 2.3 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 KFY04705.1 - 3.1e-07 31.2 0.1 5.7e-07 30.4 0.1 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_4 PF08386.10 KFY04705.1 - 0.0038 17.3 0.0 0.017 15.2 0.0 2.1 2 0 0 2 2 2 1 TAP-like protein Zn_clus PF00172.18 KFY04705.1 - 0.0056 16.8 2.6 0.0091 16.1 2.6 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Esterase PF00756.20 KFY04705.1 - 0.081 12.6 0.0 0.15 11.7 0.0 1.5 1 1 0 1 1 1 0 Putative esterase FA_hydroxylase PF04116.13 KFY04707.1 - 1.2e-15 58.0 11.1 1.2e-15 58.0 11.1 2.1 2 1 0 2 2 2 1 Fatty acid hydroxylase superfamily Phenol_monoox PF04663.12 KFY04707.1 - 0.067 13.3 1.6 0.093 12.9 0.3 2.0 2 0 0 2 2 2 0 Phenol hydroxylase conserved region Helo_like_N PF17111.5 KFY04708.1 - 3.2e-06 26.6 3.4 4.2e-06 26.3 3.4 1.2 1 0 0 1 1 1 1 Fungal N-terminal domain of STAND proteins rRNA_proc-arch PF13234.6 KFY04708.1 - 0.036 14.0 0.2 0.053 13.4 0.2 1.3 1 0 0 1 1 1 0 rRNA-processing arch domain Alph_Pro_TM PF09608.10 KFY04709.1 - 0.007 16.2 0.0 0.013 15.3 0.0 1.3 1 0 0 1 1 1 1 Putative transmembrane protein (Alph_Pro_TM) PPL5 PF18168.1 KFY04709.1 - 9.6 5.4 10.0 17 4.6 10.0 1.4 1 0 0 1 1 1 0 Prim-pol family 5 Fumble PF03630.14 KFY04710.1 - 1e-146 488.4 0.0 1.3e-146 488.0 0.0 1.2 1 0 0 1 1 1 1 Fumble RhaA PF06134.11 KFY04710.1 - 0.16 11.1 0.0 0.25 10.5 0.0 1.2 1 0 0 1 1 1 0 L-rhamnose isomerase (RhaA) GATase_6 PF13522.6 KFY04711.1 - 6.1e-13 49.1 0.4 9.3e-13 48.5 0.4 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_4 PF13230.6 KFY04711.1 - 6.3e-08 31.9 0.3 4.5e-07 29.0 0.3 2.0 1 1 0 1 1 1 1 Glutamine amidotransferases class-II GATase_7 PF13537.6 KFY04711.1 - 0.16 11.8 0.0 0.24 11.3 0.0 1.3 1 0 0 1 1 1 0 Glutamine amidotransferase domain WD40 PF00400.32 KFY04715.1 - 0.0043 17.8 0.2 9.6 7.3 0.1 3.1 3 0 0 3 3 3 3 WD domain, G-beta repeat PhyH PF05721.13 KFY04716.1 - 2.8e-05 24.5 0.0 3.8e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) F-box_4 PF15966.5 KFY04717.1 - 0.0017 18.3 0.2 0.0063 16.4 0.0 2.0 2 0 0 2 2 2 1 F-box F-box-like PF12937.7 KFY04717.1 - 0.0017 18.2 0.6 0.0046 16.8 0.6 1.8 1 0 0 1 1 1 1 F-box-like BDHCT PF08072.11 KFY04717.1 - 0.052 13.6 0.5 0.26 11.4 0.0 2.1 2 0 0 2 2 2 0 BDHCT (NUC031) domain Rpp20 PF12328.8 KFY04722.1 - 0.067 13.1 0.8 0.075 13.0 0.8 1.1 1 0 0 1 1 1 0 Rpp20 subunit of nuclear RNase MRP and P Zn_clus PF00172.18 KFY04723.1 - 4.7e-08 33.0 8.1 4.7e-08 33.0 8.1 2.0 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain NAD_binding_10 PF13460.6 KFY04724.1 - 1.6e-34 119.4 0.0 1.8e-34 119.2 0.0 1.0 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 KFY04724.1 - 0.00021 21.0 0.0 0.00027 20.6 0.0 1.5 1 1 0 1 1 1 1 NmrA-like family Epimerase PF01370.21 KFY04724.1 - 0.00031 20.3 0.0 0.00043 19.8 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 KFY04724.1 - 0.22 10.6 0.0 0.27 10.3 0.0 1.2 1 0 0 1 1 1 0 RmlD substrate binding domain ABC_tran PF00005.27 KFY04725.1 - 1.2e-46 158.6 0.1 1.4e-24 87.1 0.0 2.5 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 KFY04725.1 - 4.5e-24 85.8 3.3 9.8e-06 25.6 0.0 4.4 3 1 0 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system ABC2_membrane_3 PF12698.7 KFY04725.1 - 7e-19 68.1 45.3 2e-13 50.2 22.1 2.5 2 1 0 2 2 2 2 ABC-2 family transporter protein AAA_29 PF13555.6 KFY04725.1 - 5.8e-09 35.6 1.5 0.00016 21.3 0.4 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain SMC_N PF02463.19 KFY04725.1 - 4.6e-08 32.8 2.6 0.1 12.0 0.2 3.8 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 KFY04725.1 - 2.2e-07 31.6 2.1 0.016 15.8 0.1 2.3 2 0 0 2 2 2 2 AAA domain AAA_15 PF13175.6 KFY04725.1 - 3.1e-05 23.9 0.2 0.14 11.8 0.4 3.3 3 0 0 3 3 3 1 AAA ATPase domain RsgA_GTPase PF03193.16 KFY04725.1 - 4.8e-05 23.3 0.8 0.15 12.0 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase AAA_27 PF13514.6 KFY04725.1 - 0.00011 21.8 0.9 0.26 10.9 0.2 2.4 2 0 0 2 2 2 2 AAA domain DUF4162 PF13732.6 KFY04725.1 - 0.00052 20.7 0.0 0.003 18.2 0.0 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF4162) AAA_16 PF13191.6 KFY04725.1 - 0.0013 19.1 1.2 1.3 9.4 0.4 2.6 2 0 0 2 2 2 2 AAA ATPase domain Zeta_toxin PF06414.12 KFY04725.1 - 0.0061 15.9 0.3 6.7 5.9 0.0 3.2 3 0 0 3 3 3 1 Zeta toxin Ploopntkinase1 PF18748.1 KFY04725.1 - 0.0062 16.1 0.0 2.3 7.7 0.0 2.5 2 0 0 2 2 2 1 P-loop Nucleotide Kinase1 AAA_30 PF13604.6 KFY04725.1 - 0.0067 16.2 3.8 1.9 8.2 0.9 2.7 2 1 0 2 2 2 2 AAA domain AAA_22 PF13401.6 KFY04725.1 - 0.032 14.5 0.2 5 7.4 0.1 2.8 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.17 KFY04725.1 - 0.032 14.0 0.0 9.4 5.9 0.0 3.2 3 0 0 3 3 3 0 IstB-like ATP binding protein MukB PF04310.12 KFY04725.1 - 0.055 13.3 0.2 8 6.2 0.1 2.4 2 0 0 2 2 2 0 MukB N-terminal SRP54 PF00448.22 KFY04725.1 - 0.071 12.7 0.4 11 5.5 0.2 2.4 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_28 PF13521.6 KFY04725.1 - 0.08 13.2 1.5 3 8.1 0.7 2.4 2 0 0 2 2 2 0 AAA domain SbcCD_C PF13558.6 KFY04725.1 - 0.092 13.0 0.4 30 5.0 0.0 3.7 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_19 PF13245.6 KFY04725.1 - 0.12 12.7 0.1 5.2 7.4 0.0 2.5 2 0 0 2 2 2 0 AAA domain Rad17 PF03215.15 KFY04725.1 - 0.13 12.2 0.0 11 5.9 0.0 2.4 2 0 0 2 2 2 0 Rad17 P-loop domain Mg_chelatase PF01078.21 KFY04725.1 - 1.7 8.0 6.1 24 4.3 0.5 3.2 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI AA_permease_2 PF13520.6 KFY04726.1 - 4e-42 144.6 41.1 1.4e-41 142.7 41.1 1.8 1 1 0 1 1 1 1 Amino acid permease Nitroreductase PF00881.24 KFY04726.1 - 0.1 12.7 0.0 0.2 11.7 0.0 1.4 1 0 0 1 1 1 0 Nitroreductase family SWIM PF04434.17 KFY04727.1 - 0.15 11.8 0.4 0.33 10.7 0.4 1.5 1 0 0 1 1 1 0 SWIM zinc finger TFCD_C PF12612.8 KFY04728.1 - 1.9e-25 89.8 0.0 5.3e-25 88.4 0.0 1.8 1 0 0 1 1 1 1 Tubulin folding cofactor D C terminal HEAT_2 PF13646.6 KFY04728.1 - 0.11 12.9 12.4 0.84 10.1 0.5 5.4 6 1 0 6 6 6 0 HEAT repeats HEAT PF02985.22 KFY04728.1 - 0.46 10.9 0.0 0.46 10.9 0.0 5.9 6 0 0 6 6 6 0 HEAT repeat SSP160 PF06933.11 KFY04729.1 - 0.008 14.4 4.9 0.011 14.0 4.9 1.1 1 0 0 1 1 1 1 Special lobe-specific silk protein SSP160 PAN_4 PF14295.6 KFY04729.1 - 0.015 15.2 0.4 0.048 13.6 0.4 1.8 1 1 0 1 1 1 0 PAN domain Pilin_N PF07790.11 KFY04729.1 - 0.029 15.3 0.1 0.078 13.9 0.1 1.7 1 0 0 1 1 1 0 Archaeal Type IV pilin, N-terminal Alpha_GJ PF03229.13 KFY04729.1 - 0.051 14.1 6.3 0.1 13.2 6.3 1.4 1 0 0 1 1 1 0 Alphavirus glycoprotein J PAN_1 PF00024.26 KFY04729.1 - 0.088 12.8 0.0 0.24 11.4 0.0 1.7 1 0 0 1 1 1 0 PAN domain Acetyltransf_10 PF13673.7 KFY04730.1 - 3.7e-08 33.4 0.0 5.5e-08 32.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 KFY04730.1 - 6.3e-08 32.9 0.1 1.3e-07 31.8 0.1 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 KFY04730.1 - 2.8e-07 30.8 0.0 4.2e-07 30.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 KFY04730.1 - 0.01 15.9 0.0 0.066 13.3 0.0 2.0 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain FR47 PF08445.10 KFY04730.1 - 0.038 14.0 0.0 0.087 12.8 0.0 1.5 1 1 0 1 1 1 0 FR47-like protein Pkinase PF00069.25 KFY04731.1 - 7.6e-23 81.2 0.0 9.8e-23 80.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFY04731.1 - 1.9e-18 66.7 0.0 2.6e-18 66.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 KFY04731.1 - 0.0062 15.9 0.0 0.0099 15.2 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KFY04731.1 - 0.046 13.6 0.0 0.088 12.7 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kinase-like PF14531.6 KFY04731.1 - 0.09 12.1 0.0 0.36 10.1 0.0 1.7 1 1 0 1 1 1 0 Kinase-like RIO1 PF01163.22 KFY04731.1 - 0.093 12.3 0.0 0.14 11.7 0.0 1.2 1 0 0 1 1 1 0 RIO1 family Rsa3 PF14615.6 KFY04734.1 - 0.38 10.4 2.0 1.4 8.6 0.0 2.6 3 0 0 3 3 3 0 Ribosome-assembly protein 3 Ank_4 PF13637.6 KFY04737.1 - 5.6e-09 36.4 0.2 0.00073 20.1 0.0 2.7 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 KFY04737.1 - 3.1e-07 30.9 1.2 2.5e-05 24.8 0.1 1.8 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 KFY04737.1 - 4.7e-07 30.0 0.2 0.034 14.6 0.0 2.8 2 0 0 2 2 2 2 Ankyrin repeat NMO PF03060.15 KFY04742.1 - 6.3e-34 117.8 1.9 1e-33 117.2 1.9 1.3 1 0 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.25 KFY04742.1 - 2.4e-05 23.5 0.0 3e-05 23.2 0.0 1.1 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain ECH_1 PF00378.20 KFY04743.1 - 2.8e-49 167.7 0.0 3.8e-49 167.3 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KFY04743.1 - 8.5e-25 87.9 0.0 5.3e-24 85.3 0.0 2.1 1 1 1 2 2 2 1 Enoyl-CoA hydratase/isomerase Peptidase_S49 PF01343.18 KFY04743.1 - 0.0071 16.3 0.1 0.11 12.4 0.0 2.4 2 1 1 3 3 3 1 Peptidase family S49 Ank_4 PF13637.6 KFY04744.1 - 1.5e-47 159.4 5.2 4.2e-09 36.8 0.0 8.7 6 2 3 9 9 9 7 Ankyrin repeats (many copies) Ank_2 PF12796.7 KFY04744.1 - 7.7e-43 145.0 4.7 8.4e-12 45.5 0.1 5.6 4 2 1 5 5 5 4 Ankyrin repeats (3 copies) Ank_5 PF13857.6 KFY04744.1 - 3.7e-35 119.5 10.7 2.7e-08 33.9 0.3 8.2 4 2 5 10 10 10 8 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFY04744.1 - 1.5e-34 114.1 12.6 9.8e-05 22.5 0.0 11.4 11 1 0 11 11 11 7 Ankyrin repeat Ank PF00023.30 KFY04744.1 - 3.3e-32 109.5 20.9 0.00052 20.3 0.1 11.0 11 0 0 11 11 11 9 Ankyrin repeat Methyltransf_10 PF05971.12 KFY04745.1 - 3e-59 200.8 0.0 4.3e-59 200.3 0.0 1.2 1 0 0 1 1 1 1 RNA methyltransferase MTS PF05175.14 KFY04745.1 - 0.0028 17.2 0.0 0.0048 16.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Met_10 PF02475.16 KFY04745.1 - 0.047 13.4 0.0 0.077 12.7 0.0 1.2 1 0 0 1 1 1 0 Met-10+ like-protein PrmA PF06325.13 KFY04745.1 - 0.11 11.8 0.0 0.21 11.0 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) E1-E2_ATPase PF00122.20 KFY04747.1 - 1.2e-47 161.8 4.1 1.2e-47 161.8 4.1 2.8 4 0 0 4 4 4 1 E1-E2 ATPase Hydrolase PF00702.26 KFY04747.1 - 7.8e-18 65.5 0.0 2e-17 64.2 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 KFY04747.1 - 1.3e-11 44.0 0.0 2.7e-11 43.0 0.0 1.5 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 KFY04747.1 - 0.0028 17.4 0.1 0.0054 16.5 0.1 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 KFY04747.1 - 0.01 15.9 0.0 0.021 14.9 0.0 1.5 1 0 0 1 1 1 0 Cation transport ATPase (P-type) SPATIAL PF15256.6 KFY04747.1 - 0.013 15.8 0.1 0.024 15.0 0.1 1.3 1 0 0 1 1 1 0 SPATIAL DUF2613 PF11021.8 KFY04747.1 - 7.5 6.8 8.4 7.8 6.7 0.6 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2613) Glyco_hydro_106 PF17132.4 KFY04750.1 - 3.5e-14 52.1 0.3 2.9e-09 35.8 0.0 3.1 4 0 0 4 4 4 2 alpha-L-rhamnosidase DUF4267 PF14087.6 KFY04752.1 - 2.3e-17 63.1 0.9 2.9e-17 62.7 0.9 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4267) Hydrophobin_2 PF06766.11 KFY04753.1 - 6.1e-20 70.9 8.1 7.5e-20 70.6 8.1 1.1 1 0 0 1 1 1 1 Fungal hydrophobin eIF3_N PF09440.10 KFY04754.1 - 2.1e-48 164.1 3.5 2.1e-48 164.1 3.5 1.9 2 0 0 2 2 2 1 eIF3 subunit 6 N terminal domain PCI PF01399.27 KFY04754.1 - 5.5e-14 52.5 0.2 1.6e-13 51.0 0.2 1.9 1 0 0 1 1 1 1 PCI domain VPR PF00522.18 KFY04754.1 - 0.076 13.0 0.3 0.73 9.9 0.0 2.7 3 0 0 3 3 3 0 VPR/VPX protein Img2 PF05046.14 KFY04755.1 - 2.3e-26 91.9 0.2 3.1e-26 91.5 0.2 1.2 1 0 0 1 1 1 1 Mitochondrial large subunit ribosomal protein (Img2) ARID PF01388.21 KFY04756.1 - 6.6e-20 71.6 0.1 6.6e-20 71.6 0.1 2.7 3 0 0 3 3 3 1 ARID/BRIGHT DNA binding domain BAF250_C PF12031.8 KFY04756.1 - 0.0084 15.4 0.2 0.028 13.7 0.2 1.9 1 0 0 1 1 1 1 SWI/SNF-like complex subunit BAF250/Osa EVE PF01878.18 KFY04758.1 - 2.1e-06 27.8 2.1 3.6e-05 23.8 0.0 2.2 2 0 0 2 2 2 2 EVE domain KI67R PF08065.12 KFY04758.1 - 0.47 11.0 13.2 1.3 9.6 11.9 1.9 1 1 1 2 2 2 0 KI67R (NUC007) repeat SPX PF03105.19 KFY04759.1 - 5.8e-06 26.5 0.5 0.012 15.6 0.0 2.0 1 1 1 2 2 2 2 SPX domain Fic PF02661.18 KFY04760.1 - 3.3e-14 53.5 0.0 1.7e-13 51.3 0.0 2.1 1 1 0 1 1 1 1 Fic/DOC family DUF2382 PF09557.10 KFY04760.1 - 0.012 15.9 0.3 0.036 14.3 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF2382) Ald_Xan_dh_C2 PF02738.18 KFY04761.1 - 1.9e-206 686.8 2.6 2.7e-206 686.3 2.6 1.2 1 0 0 1 1 1 1 Molybdopterin-binding domain of aldehyde dehydrogenase FAD_binding_5 PF00941.21 KFY04761.1 - 3.5e-46 157.1 0.0 7.5e-46 156.0 0.0 1.6 1 0 0 1 1 1 1 FAD binding domain in molybdopterin dehydrogenase CO_deh_flav_C PF03450.17 KFY04761.1 - 1.2e-33 115.4 0.1 4.2e-33 113.6 0.0 2.1 2 0 0 2 2 2 1 CO dehydrogenase flavoprotein C-terminal domain Ald_Xan_dh_C PF01315.22 KFY04761.1 - 1.9e-29 102.2 0.0 5.7e-29 100.7 0.0 1.9 2 0 0 2 2 2 1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain Fer2_2 PF01799.20 KFY04761.1 - 5.3e-29 100.1 0.1 1.2e-28 98.9 0.1 1.7 1 0 0 1 1 1 1 [2Fe-2S] binding domain Fer2 PF00111.27 KFY04761.1 - 3.8e-08 33.2 0.2 2.1e-07 30.8 0.0 2.5 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain adh_short PF00106.25 KFY04762.1 - 8.3e-23 80.9 0.0 3.3e-20 72.4 0.0 2.2 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KFY04762.1 - 1.9e-13 50.5 0.0 1.5e-11 44.3 0.0 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KFY04762.1 - 2.2e-09 37.5 0.0 3.2e-09 36.9 0.0 1.3 1 0 0 1 1 1 1 KR domain GDP_Man_Dehyd PF16363.5 KFY04762.1 - 0.00054 19.5 0.0 0.00091 18.7 0.0 1.3 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 KFY04762.1 - 0.0044 16.5 0.0 0.0076 15.7 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF3425 PF11905.8 KFY04763.1 - 6.6e-18 64.9 0.0 1.5e-16 60.5 0.0 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF3425) AflR PF08493.10 KFY04764.1 - 3e-18 66.3 5.0 5.8e-18 65.4 5.0 1.4 1 0 0 1 1 1 1 Aflatoxin regulatory protein Zn_clus PF00172.18 KFY04764.1 - 2.9e-07 30.5 8.2 6.1e-07 29.5 8.2 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Lactamase_B PF00753.27 KFY04766.1 - 1.4e-15 57.9 2.7 2.3e-14 53.9 2.7 2.2 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 KFY04766.1 - 0.00013 21.6 0.1 0.00026 20.6 0.1 1.6 1 0 0 1 1 1 1 Beta-lactamase superfamily domain BLACT_WH PF17778.1 KFY04766.1 - 0.00069 19.5 0.1 0.0024 17.8 0.1 2.0 1 1 0 1 1 1 1 Beta-lactamase associated winged helix domain Lactamase_B_3 PF13483.6 KFY04766.1 - 0.15 11.9 0.1 0.34 10.8 0.1 1.5 1 1 0 1 1 1 0 Beta-lactamase superfamily domain ketoacyl-synt PF00109.26 KFY04767.1 - 7.7e-71 238.6 0.0 2.3e-70 237.1 0.0 1.8 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain SAT PF16073.5 KFY04767.1 - 6.5e-51 173.4 0.1 7.4e-50 169.9 0.0 2.5 2 0 0 2 2 2 1 Starter unit:ACP transacylase in aflatoxin biosynthesis Acyl_transf_1 PF00698.21 KFY04767.1 - 1e-43 150.1 0.0 2.9e-43 148.6 0.0 1.8 2 0 0 2 2 2 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 KFY04767.1 - 9.3e-34 116.0 0.7 3e-33 114.3 0.7 2.0 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain PP-binding PF00550.25 KFY04767.1 - 4.7e-09 36.5 1.3 1.3e-08 35.0 1.3 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site PS-DH PF14765.6 KFY04767.1 - 6.2e-09 35.5 0.0 1.1e-08 34.7 0.0 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase KAsynt_C_assoc PF16197.5 KFY04767.1 - 1.7e-08 34.9 0.1 5.2e-08 33.3 0.0 1.9 2 0 0 2 2 2 1 Ketoacyl-synthetase C-terminal extension Thiolase_N PF00108.23 KFY04767.1 - 1.6e-06 27.7 0.1 4.2e-06 26.3 0.1 1.6 1 0 0 1 1 1 1 Thiolase, N-terminal domain BBE PF08031.12 KFY04768.1 - 0.002 18.2 0.0 0.0043 17.1 0.0 1.6 1 0 0 1 1 1 1 Berberine and berberine like Pec_lyase_C PF00544.19 KFY04769.1 - 4.2e-37 127.8 9.5 5.8e-37 127.3 9.5 1.1 1 0 0 1 1 1 1 Pectate lyase Beta_helix PF13229.6 KFY04769.1 - 0.0019 18.1 13.9 0.035 13.9 14.0 2.4 1 1 0 1 1 1 1 Right handed beta helix region Ribonuclease_T2 PF00445.18 KFY04770.1 - 1.1e-41 143.0 0.2 2.1e-41 142.1 0.2 1.4 1 0 0 1 1 1 1 Ribonuclease T2 family AAA_2 PF07724.14 KFY04770.1 - 5.1e-06 26.7 0.0 8e-06 26.1 0.0 1.2 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) HET PF06985.11 KFY04771.1 - 5e-12 46.4 8.1 1.5e-09 38.4 0.6 2.9 2 1 1 3 3 3 2 Heterokaryon incompatibility protein (HET) Rxt3 PF08642.10 KFY04772.1 - 3.8e-43 147.3 1.2 8.3e-43 146.2 0.0 2.3 2 0 0 2 2 2 1 Histone deacetylation protein Rxt3 LCCL PF03815.19 KFY04772.1 - 3.1e-05 24.0 0.0 0.00064 19.8 0.0 2.3 2 0 0 2 2 2 1 LCCL domain CLN3 PF02487.17 KFY04773.1 - 4.5e-161 536.3 4.0 1.3e-160 534.8 4.0 1.9 1 0 0 1 1 1 1 CLN3 protein Dynactin PF12455.8 KFY04773.1 - 9.6e-111 369.6 8.6 9.6e-111 369.6 8.6 3.0 2 1 0 3 3 3 1 Dynein associated protein CAP_GLY PF01302.25 KFY04773.1 - 1.2e-22 79.6 0.4 2.2e-22 78.8 0.4 1.4 1 0 0 1 1 1 1 CAP-Gly domain Abdominal-A PF12407.8 KFY04773.1 - 1.1 9.0 5.5 3.1 7.4 5.5 1.8 1 0 0 1 1 1 0 Homeobox protein Aa_trans PF01490.18 KFY04774.1 - 3e-52 177.7 39.3 3.7e-52 177.4 39.3 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein ATG27 PF09451.10 KFY04774.1 - 0.23 11.3 0.6 0.4 10.5 0.6 1.3 1 0 0 1 1 1 0 Autophagy-related protein 27 DUF2721 PF11026.8 KFY04774.1 - 8.5 6.3 25.3 8.4 6.3 3.9 4.9 3 2 1 5 5 5 0 Protein of unknown function (DUF2721) YjbH PF06082.11 KFY04776.1 - 5.1 5.8 25.4 8.6 5.0 25.4 1.3 1 0 0 1 1 1 0 Exopolysaccharide biosynthesis protein YbjH 6PF2K PF01591.18 KFY04777.1 - 2.4e-82 275.6 0.1 3e-82 275.2 0.1 1.1 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.22 KFY04777.1 - 3.3e-33 115.0 0.0 6.2e-33 114.1 0.0 1.4 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) KTI12 PF08433.10 KFY04777.1 - 5e-05 22.9 0.0 7.3e-05 22.4 0.0 1.2 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_33 PF13671.6 KFY04777.1 - 0.00016 21.8 0.0 0.00032 20.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain Atracotoxin PF05353.11 KFY04777.1 - 0.13 12.4 0.1 0.25 11.4 0.1 1.4 1 0 0 1 1 1 0 Delta Atracotoxin CorA PF01544.18 KFY04779.1 - 7.5e-07 28.8 4.4 1.4e-06 27.8 3.9 1.7 1 1 1 2 2 2 1 CorA-like Mg2+ transporter protein NPV_P10 PF05531.12 KFY04779.1 - 0.11 12.9 3.1 6.6 7.3 0.0 2.4 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein DUF5619 PF18505.1 KFY04779.1 - 0.14 12.2 0.0 0.36 10.8 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF5619) DUF1214 PF06742.11 KFY04780.1 - 0.00021 21.7 0.0 0.14 12.6 0.0 2.6 2 0 0 2 2 2 2 Protein of unknown function (DUF1214) GPI-anchored PF10342.9 KFY04780.1 - 0.16 12.8 0.8 1 10.2 0.1 2.6 3 0 0 3 3 3 0 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family He_PIG PF05345.12 KFY04780.1 - 0.22 11.7 2.5 4.2 7.6 0.3 2.9 2 0 0 2 2 2 0 Putative Ig domain COX4_pro PF03626.14 KFY04780.1 - 0.34 11.4 3.4 0.25 11.8 0.5 2.4 2 0 0 2 2 2 0 Prokaryotic Cytochrome C oxidase subunit IV Fungal_trans PF04082.18 KFY04781.1 - 5.6e-68 228.9 0.2 8.6e-68 228.2 0.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.26 KFY04781.1 - 8.6e-07 29.1 9.6 0.00032 21.0 0.6 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 KFY04781.1 - 0.012 16.0 1.1 0.012 16.0 1.1 3.0 3 0 0 3 3 3 0 Zinc-finger double domain zf-C2H2_4 PF13894.6 KFY04781.1 - 0.057 14.3 0.6 0.057 14.3 0.6 3.3 3 0 0 3 3 3 0 C2H2-type zinc finger Pkinase PF00069.25 KFY04785.1 - 9.9e-49 166.1 0.0 1.4e-48 165.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFY04785.1 - 2.9e-27 95.6 0.3 4.3e-26 91.7 0.3 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 KFY04785.1 - 0.075 11.8 0.0 0.15 10.8 0.0 1.4 1 0 0 1 1 1 0 Fungal protein kinase Kinase-like PF14531.6 KFY04785.1 - 0.29 10.4 0.3 0.55 9.5 0.1 1.5 2 0 0 2 2 2 0 Kinase-like Dicty_CAR PF05462.11 KFY04789.1 - 1e-16 61.0 5.7 1e-16 61.0 5.7 1.9 2 0 0 2 2 2 1 Slime mold cyclic AMP receptor 7tm_2 PF00002.24 KFY04789.1 - 9.3e-08 31.7 5.4 1.9e-07 30.6 5.4 1.4 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) Git3 PF11710.8 KFY04789.1 - 5.1e-07 29.7 11.6 1e-06 28.7 11.6 1.4 1 0 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 7TM_GPCR_Srsx PF10320.9 KFY04789.1 - 0.00014 21.3 4.8 0.00026 20.5 4.8 1.4 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx CATSPERG PF15064.6 KFY04789.1 - 0.059 11.2 1.5 2.6 5.7 0.1 2.1 1 1 1 2 2 2 0 Cation channel sperm-associated protein subunit gamma Put_Phosphatase PF06888.12 KFY04789.1 - 0.17 11.2 0.0 22 4.4 0.0 2.2 2 0 0 2 2 2 0 Putative Phosphatase DUF1242 PF06842.12 KFY04789.1 - 0.27 11.1 1.6 28 4.6 0.1 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1242) Zn_clus PF00172.18 KFY04793.1 - 5.2e-07 29.7 8.9 8e-07 29.1 8.9 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 KFY04793.1 - 0.00086 18.2 0.2 0.0016 17.3 0.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain GPI2 PF06432.11 KFY04794.1 - 0.05 13.0 0.0 0.062 12.7 0.0 1.2 1 0 0 1 1 1 0 Phosphatidylinositol N-acetylglucosaminyltransferase Beach PF02138.18 KFY04795.1 - 7.3e-117 389.6 0.0 1.5e-116 388.6 0.0 1.6 1 0 0 1 1 1 1 Beige/BEACH domain HLH PF00010.26 KFY04795.1 - 2.8e-16 59.2 0.3 8.5e-16 57.7 0.3 1.9 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Laminin_G_3 PF13385.6 KFY04795.1 - 1.2e-10 41.8 0.1 2.8e-10 40.5 0.1 1.6 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily PH_BEACH PF14844.6 KFY04795.1 - 4.1e-09 36.4 0.0 1.3e-08 34.8 0.0 1.9 1 0 0 1 1 1 1 PH domain associated with Beige/BEACH WD40 PF00400.32 KFY04795.1 - 0.00062 20.5 1.3 0.11 13.4 0.0 4.4 4 1 0 4 4 4 1 WD domain, G-beta repeat DUF4704 PF15787.5 KFY04795.1 - 0.0025 17.1 0.0 0.025 13.8 0.0 2.5 2 0 0 2 2 2 1 Domain of unknown function (DUF4704) Peptidase_S8 PF00082.22 KFY04796.1 - 1.7e-33 116.1 9.8 2e-33 115.9 8.8 1.5 1 1 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.16 KFY04796.1 - 1.1e-19 70.8 0.2 2.9e-19 69.5 0.2 1.7 1 0 0 1 1 1 1 Peptidase inhibitor I9 Pkinase PF00069.25 KFY04798.1 - 1e-62 211.9 0.0 1.5e-62 211.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFY04798.1 - 1.6e-29 103.0 0.0 2.3e-29 102.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Abhydrolase_1 PF00561.20 KFY04798.1 - 6.8e-22 78.3 0.1 4.1e-21 75.8 0.1 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydro_lipase PF04083.16 KFY04798.1 - 1.3e-21 75.9 0.0 2.6e-21 74.9 0.0 1.5 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Kinase-like PF14531.6 KFY04798.1 - 0.00025 20.5 0.0 0.00039 19.8 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Hydrolase_4 PF12146.8 KFY04798.1 - 0.00064 19.1 0.0 0.045 13.0 0.0 2.3 1 1 0 1 1 1 1 Serine aminopeptidase, S33 FSH1 PF03959.13 KFY04798.1 - 0.0021 17.7 0.0 0.098 12.3 0.0 2.2 1 1 0 1 1 1 1 Serine hydrolase (FSH1) APH PF01636.23 KFY04798.1 - 0.017 15.1 0.0 0.03 14.2 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Haspin_kinase PF12330.8 KFY04798.1 - 0.04 12.9 0.1 0.086 11.8 0.0 1.5 2 0 0 2 2 2 0 Haspin like kinase domain Pkinase_fungal PF17667.1 KFY04798.1 - 0.041 12.7 0.0 0.072 11.9 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase RRM_1 PF00076.22 KFY04799.1 - 2.4e-14 52.9 0.0 5e-14 51.9 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 KFY04799.1 - 0.0016 18.4 0.0 0.003 17.5 0.0 1.4 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif DUF2457 PF10446.9 KFY04799.1 - 0.024 13.8 3.1 0.041 13.0 3.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) NPBW PF15180.6 KFY04799.1 - 0.08 12.8 0.5 5.2 7.0 0.1 2.6 3 0 0 3 3 3 0 Neuropeptides B and W Methyltransf_3 PF01596.17 KFY04800.1 - 1.2e-34 119.4 0.0 1.8e-34 118.8 0.0 1.3 1 1 0 1 1 1 1 O-methyltransferase Methyltransf_31 PF13847.6 KFY04800.1 - 6.3e-11 42.3 0.0 9e-11 41.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_24 PF13578.6 KFY04800.1 - 1.2e-10 42.3 0.0 1.1e-09 39.2 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain PCMT PF01135.19 KFY04800.1 - 2.6e-10 40.4 0.0 3.4e-10 40.0 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_25 PF13649.6 KFY04800.1 - 3.4e-08 34.1 0.0 5.8e-08 33.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain GCD14 PF08704.10 KFY04800.1 - 0.00026 20.7 0.0 0.0004 20.1 0.0 1.2 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit Ubie_methyltran PF01209.18 KFY04800.1 - 0.00086 18.7 0.0 0.0011 18.4 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Cons_hypoth95 PF03602.15 KFY04800.1 - 0.014 15.0 0.0 0.02 14.5 0.0 1.2 1 0 0 1 1 1 0 Conserved hypothetical protein 95 Fibrillarin PF01269.17 KFY04800.1 - 0.04 13.0 0.0 0.05 12.7 0.0 1.2 1 0 0 1 1 1 0 Fibrillarin Methyltransf_4 PF02390.17 KFY04800.1 - 0.16 11.4 0.0 0.31 10.5 0.0 1.4 1 0 0 1 1 1 0 Putative methyltransferase PNTB PF02233.16 KFY04806.1 - 1.2e-172 575.0 24.1 1.2e-172 575.0 24.1 2.1 2 0 0 2 2 2 1 NAD(P) transhydrogenase beta subunit Arylsulfotran_2 PF14269.6 KFY04806.1 - 3.5e-74 249.9 2.5 5.3e-74 249.3 2.5 1.3 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) AlaDh_PNT_C PF01262.21 KFY04806.1 - 4.2e-74 248.4 0.3 9.9e-74 247.2 0.3 1.7 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain AlaDh_PNT_N PF05222.15 KFY04806.1 - 6.8e-38 130.0 0.0 1.8e-37 128.6 0.0 1.8 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, N-terminal domain PNTB_4TM PF12769.7 KFY04806.1 - 2.3e-30 104.9 2.8 2.3e-30 104.9 2.8 3.9 3 1 1 4 4 4 1 4TM region of pyridine nucleotide transhydrogenase, mitoch Arylsulfotrans PF05935.11 KFY04806.1 - 2.1e-16 59.8 0.8 1.7e-15 56.8 0.8 2.0 1 1 0 1 1 1 1 Arylsulfotransferase (ASST) TPP_enzyme_M PF00205.22 KFY04806.1 - 0.017 14.9 0.2 0.068 12.9 0.2 2.1 1 1 0 1 1 1 0 Thiamine pyrophosphate enzyme, central domain 2-Hacid_dh_C PF02826.19 KFY04806.1 - 0.023 14.0 0.4 0.93 8.8 0.1 2.6 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Pyr_redox_2 PF07992.14 KFY04806.1 - 0.045 13.0 0.3 0.1 11.8 0.3 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 KFY04806.1 - 0.12 11.4 0.8 0.24 10.4 0.8 1.5 1 0 0 1 1 1 0 Glucose inhibited division protein A MFS_1 PF07690.16 KFY04807.1 - 4.4e-42 144.3 30.4 4.4e-42 144.3 30.4 2.4 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KFY04807.1 - 9.9e-15 54.3 20.6 8e-12 44.8 11.0 2.4 2 0 0 2 2 2 2 Sugar (and other) transporter Peptidase_C41 PF05417.11 KFY04807.1 - 0.13 12.1 0.0 0.25 11.2 0.0 1.4 1 0 0 1 1 1 0 Hepatitis E cysteine protease MFS_1 PF07690.16 KFY04808.1 - 3.1e-27 95.4 20.6 4e-27 95.1 20.6 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF1996 PF09362.10 KFY04809.1 - 4.5e-49 167.6 2.2 1.6e-27 97.0 0.0 2.1 1 1 1 2 2 2 2 Domain of unknown function (DUF1996) Dickkopf_N PF04706.12 KFY04810.1 - 0.12 12.9 0.1 0.19 12.2 0.1 1.3 1 0 0 1 1 1 0 Dickkopf N-terminal cysteine-rich region FMO-like PF00743.19 KFY04811.1 - 3.9e-16 58.6 0.0 7.5e-14 51.0 0.0 2.2 2 0 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 KFY04811.1 - 4.7e-10 39.2 0.0 7.8e-10 38.5 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KFY04811.1 - 2.1e-07 31.1 0.0 6.1e-07 29.6 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 KFY04811.1 - 2.5e-07 30.3 0.1 0.0027 17.0 0.0 2.9 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KFY04811.1 - 0.00014 21.6 0.3 0.42 10.2 0.1 3.2 3 0 0 3 3 3 2 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 KFY04811.1 - 0.0011 19.0 0.0 0.0039 17.2 0.0 2.1 1 1 0 1 1 1 1 FAD-NAD(P)-binding HI0933_like PF03486.14 KFY04811.1 - 0.0021 16.8 0.1 0.0044 15.8 0.1 1.5 2 0 0 2 2 2 1 HI0933-like protein Amino_oxidase PF01593.24 KFY04811.1 - 0.0049 16.2 0.0 0.013 14.8 0.0 1.6 1 1 1 2 2 2 1 Flavin containing amine oxidoreductase Pyr_redox PF00070.27 KFY04811.1 - 0.029 14.9 0.1 5.3 7.7 0.0 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KFY04811.1 - 0.035 13.3 0.1 0.064 12.5 0.1 1.4 1 0 0 1 1 1 0 Thi4 family FAD_binding_2 PF00890.24 KFY04811.1 - 0.069 12.2 0.0 0.11 11.5 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain K_oxygenase PF13434.6 KFY04811.1 - 0.079 12.1 0.0 0.16 11.0 0.0 1.5 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) FAD_binding_3 PF01494.19 KFY04811.1 - 0.16 11.2 0.0 0.32 10.2 0.0 1.4 1 0 0 1 1 1 0 FAD binding domain Amidohydro_3 PF07969.11 KFY04812.1 - 2.1e-20 73.7 2.2 3.2e-13 50.0 0.5 2.3 1 1 0 2 2 2 2 Amidohydrolase family Amidohydro_1 PF01979.20 KFY04812.1 - 4e-20 72.4 1.7 1.8e-18 67.0 1.7 2.1 1 1 0 1 1 1 1 Amidohydrolase family Fungal_trans_2 PF11951.8 KFY04813.1 - 0.13 11.0 0.1 0.28 10.0 0.0 1.4 2 0 0 2 2 2 0 Fungal specific transcription factor domain Aldose_epim PF01263.20 KFY04814.1 - 2.4e-47 161.7 0.4 3e-47 161.4 0.4 1.1 1 0 0 1 1 1 1 Aldose 1-epimerase Ank_2 PF12796.7 KFY04816.1 - 6.8e-75 247.7 1.9 2.8e-15 56.7 0.0 9.0 4 3 4 8 8 8 7 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KFY04816.1 - 6.5e-59 188.9 0.9 0.001 19.4 0.0 15.1 15 0 0 15 15 15 11 Ankyrin repeat Ank PF00023.30 KFY04816.1 - 2.5e-54 179.4 8.2 0.00058 20.2 0.0 14.5 14 0 0 14 14 14 9 Ankyrin repeat Ank_4 PF13637.6 KFY04816.1 - 2.2e-51 171.6 0.5 2.5e-07 31.1 0.0 11.1 6 6 5 12 12 12 12 Ankyrin repeats (many copies) Ank_5 PF13857.6 KFY04816.1 - 2.1e-41 139.4 4.4 1.2e-06 28.6 0.0 10.4 6 2 5 11 11 11 10 Ankyrin repeats (many copies) VWA_3_C PF18571.1 KFY04816.1 - 2.1e-05 24.3 10.1 26 4.8 0.1 7.9 8 0 0 8 8 8 0 von Willebrand factor type A C-terminal domain MBT PF02820.18 KFY04816.1 - 0.021 15.2 0.0 37 4.8 0.0 3.5 4 0 0 4 4 4 0 mbt repeat DUF5474 PF17568.2 KFY04816.1 - 0.15 12.2 0.1 58 3.8 0.0 3.7 2 1 1 3 3 3 0 Family of unknown function (DUF5474) PH PF00169.29 KFY04823.1 - 4.6e-05 23.9 0.0 0.00012 22.6 0.0 1.7 2 0 0 2 2 2 1 PH domain PH_9 PF15410.6 KFY04823.1 - 0.0026 18.1 0.0 0.0067 16.8 0.0 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain FMO-like PF00743.19 KFY04828.1 - 5.9e-22 77.8 1.9 7.1e-18 64.3 0.3 2.9 2 1 0 2 2 2 2 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.6 KFY04828.1 - 1.6e-11 44.3 0.0 4.3e-11 42.9 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.6 KFY04828.1 - 4.3e-10 39.2 0.1 2e-05 23.9 0.0 4.1 3 1 1 4 4 4 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.6 KFY04828.1 - 8.9e-10 38.3 0.0 1.5e-08 34.2 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KFY04828.1 - 1.9e-09 37.2 0.0 3.3e-06 26.5 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 KFY04828.1 - 0.00058 19.9 0.8 0.4 10.7 0.0 3.0 3 0 0 3 3 3 2 FAD-NAD(P)-binding DAO PF01266.24 KFY04828.1 - 0.00091 18.9 0.0 0.4 10.2 0.0 2.5 2 0 0 2 2 2 2 FAD dependent oxidoreductase Thi4 PF01946.17 KFY04828.1 - 0.022 14.0 0.3 0.15 11.3 0.0 2.3 3 0 0 3 3 3 0 Thi4 family GIDA PF01134.22 KFY04828.1 - 0.1 11.7 0.3 6.6 5.7 0.0 2.3 2 0 0 2 2 2 0 Glucose inhibited division protein A Fe-ADH PF00465.19 KFY04829.1 - 1.1e-64 218.5 0.0 1.5e-64 218.2 0.0 1.0 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.6 KFY04829.1 - 0.00018 21.3 0.1 0.0094 15.7 0.0 2.2 2 0 0 2 2 2 2 Iron-containing alcohol dehydrogenase FtsK_alpha PF17854.1 KFY04829.1 - 0.14 12.3 0.0 0.38 10.9 0.0 1.7 1 1 0 1 1 1 0 FtsK alpha domain Zn_clus PF00172.18 KFY04830.1 - 8.3e-09 35.4 4.8 1.6e-08 34.5 4.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 KFY04830.1 - 8.7e-06 24.8 3.1 7.6e-05 21.7 3.1 2.1 1 1 0 1 1 1 1 Fungal specific transcription factor domain Sugar_tr PF00083.24 KFY04831.1 - 1e-80 271.9 28.7 1.2e-80 271.7 28.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KFY04831.1 - 1e-17 64.1 32.5 1e-17 64.1 32.5 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily AMP-binding PF00501.28 KFY04832.1 - 2.6e-87 293.2 0.1 2.1e-85 286.9 0.0 2.1 2 0 0 2 2 2 2 AMP-binding enzyme Abhydrolase_3 PF07859.13 KFY04832.1 - 9.5e-52 175.9 0.0 1.6e-51 175.2 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold AMP-binding_C PF13193.6 KFY04832.1 - 4.5e-10 40.4 0.0 1.8e-09 38.4 0.0 2.1 2 1 0 2 2 2 1 AMP-binding enzyme C-terminal domain COesterase PF00135.28 KFY04832.1 - 7.8e-07 28.3 0.0 1.9e-06 27.1 0.0 1.5 1 1 0 1 1 1 1 Carboxylesterase family Thiolase_N PF00108.23 KFY04833.1 - 1e-88 297.1 0.3 1.5e-88 296.5 0.3 1.2 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 KFY04833.1 - 4.1e-38 129.8 0.4 4.1e-38 129.8 0.4 1.7 2 0 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 KFY04833.1 - 9.7e-07 28.6 2.1 1.5e-06 28.0 0.8 1.9 2 1 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Aldo_ket_red PF00248.21 KFY04836.1 - 9.4e-52 176.0 0.0 1.1e-51 175.8 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family ROKNT PF08067.11 KFY04836.1 - 0.19 12.0 0.3 0.36 11.1 0.3 1.4 1 0 0 1 1 1 0 ROKNT (NUC014) domain Esterase_phd PF10503.9 KFY04837.1 - 2.5e-22 79.5 2.7 3.3e-22 79.1 2.7 1.1 1 0 0 1 1 1 1 Esterase PHB depolymerase Peptidase_S9 PF00326.21 KFY04837.1 - 5e-13 49.0 0.4 7.1e-13 48.5 0.4 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family CBM_1 PF00734.18 KFY04837.1 - 8.5e-05 22.4 6.8 8.5e-05 22.4 6.8 2.9 3 0 0 3 3 3 1 Fungal cellulose binding domain FSH1 PF03959.13 KFY04837.1 - 0.023 14.4 0.0 0.032 13.9 0.0 1.2 1 0 0 1 1 1 0 Serine hydrolase (FSH1) Esterase PF00756.20 KFY04837.1 - 0.025 14.2 1.3 0.036 13.7 0.5 1.7 2 0 0 2 2 2 0 Putative esterase Abhydrolase_1 PF00561.20 KFY04837.1 - 0.088 12.4 1.9 0.27 10.9 1.9 1.9 1 1 0 1 1 1 0 alpha/beta hydrolase fold DUF2920 PF11144.8 KFY04837.1 - 0.098 11.8 0.3 0.14 11.3 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2920) Abhydrolase_2 PF02230.16 KFY04837.1 - 0.13 12.0 1.2 0.58 9.9 1.2 2.2 1 1 0 1 1 1 0 Phospholipase/Carboxylesterase Ribonuclease PF00545.20 KFY04838.1 - 5.1e-10 40.0 0.0 6.8e-10 39.6 0.0 1.1 1 0 0 1 1 1 1 ribonuclease DUF3632 PF12311.8 KFY04839.1 - 3.2e-37 128.6 1.4 3.9e-37 128.3 1.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3632) Epimerase PF01370.21 KFY04840.1 - 4.8e-11 42.6 0.0 7.1e-11 42.0 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 KFY04840.1 - 4.6e-10 39.7 0.0 7.9e-10 38.9 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 KFY04840.1 - 1e-06 28.5 0.2 2e-06 27.6 0.2 1.5 1 0 0 1 1 1 1 NmrA-like family Polysacc_synt_2 PF02719.15 KFY04840.1 - 4.3e-05 22.8 0.0 0.0001 21.6 0.1 1.5 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.12 KFY04840.1 - 5.5e-05 22.5 0.6 0.00058 19.1 0.6 2.2 1 1 0 1 1 1 1 Male sterility protein GDP_Man_Dehyd PF16363.5 KFY04840.1 - 0.00023 20.7 0.0 0.00043 19.8 0.0 1.4 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 KFY04840.1 - 0.0023 17.0 0.0 0.0028 16.7 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 KFY04840.1 - 0.0025 17.0 0.0 0.046 12.8 0.0 2.1 2 0 0 2 2 2 1 RmlD substrate binding domain KR PF08659.10 KFY04840.1 - 0.0039 17.1 0.0 0.0088 16.0 0.0 1.6 1 0 0 1 1 1 1 KR domain F420_oxidored PF03807.17 KFY04840.1 - 0.012 16.1 0.0 0.028 15.0 0.0 1.7 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent adh_short PF00106.25 KFY04840.1 - 0.014 14.8 0.0 0.025 14.0 0.0 1.5 1 0 0 1 1 1 0 short chain dehydrogenase NAD_binding_3 PF03447.16 KFY04840.1 - 0.035 14.8 0.0 0.066 13.9 0.0 1.4 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain ApbA PF02558.16 KFY04840.1 - 0.039 13.6 0.0 0.076 12.7 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA SpoU_methylas_C PF12105.8 KFY04840.1 - 0.051 13.3 0.0 0.098 12.4 0.0 1.4 1 0 0 1 1 1 0 SpoU, rRNA methylase, C-terminal Sacchrp_dh_NADP PF03435.18 KFY04840.1 - 0.057 13.7 0.0 0.11 12.7 0.0 1.5 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain FAM180 PF15173.6 KFY04840.1 - 0.091 12.8 0.0 0.17 11.9 0.0 1.4 1 0 0 1 1 1 0 FAM180 family NAD_binding_2 PF03446.15 KFY04840.1 - 0.1 12.8 0.0 0.18 12.0 0.0 1.5 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase NUDIX_2 PF13869.6 KFY04841.1 - 1.1e-81 272.9 0.0 1.3e-81 272.6 0.0 1.0 1 0 0 1 1 1 1 Nucleotide hydrolase UPF0047 PF01894.17 KFY04842.1 - 4.7e-37 126.7 0.0 2.3e-36 124.4 0.0 2.2 3 0 0 3 3 3 1 Uncharacterised protein family UPF0047 Fungal_trans PF04082.18 KFY04842.1 - 8.4e-12 44.7 0.3 1.7e-11 43.6 0.0 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KFY04842.1 - 5.6e-08 32.8 10.2 9.3e-08 32.1 10.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CoaE PF01121.20 KFY04843.1 - 2.3e-42 144.7 0.0 3.6e-42 144.0 0.0 1.2 1 0 0 1 1 1 1 Dephospho-CoA kinase Peptidase_M16_C PF05193.21 KFY04844.1 - 0.00022 21.3 0.0 0.00055 20.0 0.0 1.7 2 0 0 2 2 2 1 Peptidase M16 inactive domain Glyco_hydro_18 PF00704.28 KFY04848.1 - 1e-44 153.6 0.1 1.9e-44 152.7 0.1 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 p450 PF00067.22 KFY04848.1 - 1.1e-39 136.5 0.0 1.5e-38 132.8 0.0 2.1 1 1 0 1 1 1 1 Cytochrome P450 Hce2 PF14856.6 KFY04848.1 - 3e-21 75.6 0.8 1.2e-20 73.7 0.8 2.2 1 0 0 1 1 1 1 Pathogen effector; putative necrosis-inducing factor HATPase_c PF02518.26 KFY04848.1 - 1.2e-17 64.5 0.0 2.4e-17 63.4 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 KFY04848.1 - 5.6e-12 45.5 0.0 1.4e-11 44.3 0.0 1.7 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain LysM PF01476.20 KFY04848.1 - 0.00011 22.2 0.0 0.025 14.6 0.0 2.8 2 0 0 2 2 2 1 LysM domain Chitin_bind_1 PF00187.19 KFY04848.1 - 0.00069 20.0 8.1 0.00069 20.0 8.1 2.9 2 1 0 2 2 2 1 Chitin recognition protein LysM PF01476.20 KFY04850.1 - 2e-11 43.8 3.4 0.0035 17.4 0.0 4.3 4 0 0 4 4 4 4 LysM domain UPF0203 PF05254.12 KFY04850.1 - 0.0028 17.9 8.3 3.2 8.1 0.2 3.5 3 0 0 3 3 3 3 Uncharacterised protein family (UPF0203) DUF1153 PF06627.11 KFY04850.1 - 0.032 14.4 0.1 17 5.7 0.0 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF1153) Glyco_hydro_108 PF05838.12 KFY04850.1 - 0.1 13.1 0.0 13 6.3 0.0 2.7 2 1 0 2 2 2 0 Glycosyl hydrolase 108 DUF4358 PF14270.6 KFY04850.1 - 0.12 12.7 0.0 12 6.3 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4358) DUF4203 PF13886.6 KFY04852.1 - 1.8e-47 161.6 26.5 1.8e-47 161.6 26.5 1.4 2 0 0 2 2 2 1 Domain of unknown function (DUF4203) Mucin PF01456.17 KFY04852.1 - 0.016 15.2 9.4 0.029 14.3 9.4 1.4 1 0 0 1 1 1 0 Mucin-like glycoprotein MGC-24 PF05283.11 KFY04852.1 - 0.52 10.8 5.1 1.1 9.7 5.1 1.5 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin Miga PF10265.9 KFY04852.1 - 2.5 7.0 4.2 11 4.8 0.1 2.0 2 0 0 2 2 2 0 Mitoguardin SSB PF00436.25 KFY04853.1 - 3.1e-18 65.7 0.0 3.7e-18 65.5 0.0 1.1 1 0 0 1 1 1 1 Single-strand binding protein family NigD_N PF12667.7 KFY04853.1 - 0.13 12.4 0.0 0.2 11.8 0.0 1.3 1 0 0 1 1 1 0 NigD-like N-terminal OB domain GSH_synth_ATP PF03917.17 KFY04856.1 - 2.2e-141 471.0 0.0 2.5e-141 470.8 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic glutathione synthase, ATP binding domain GSH_synthase PF03199.15 KFY04856.1 - 7.3e-35 119.5 0.0 1.3e-34 118.7 0.0 1.4 1 0 0 1 1 1 1 Eukaryotic glutathione synthase SNF2_N PF00176.23 KFY04857.1 - 2.4e-36 125.2 0.0 3.9e-36 124.5 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 KFY04857.1 - 1.8e-22 79.7 0.0 5.2e-22 78.3 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 KFY04857.1 - 0.0017 18.4 0.0 0.0051 16.8 0.0 1.9 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_14 PF13173.6 KFY04857.1 - 0.033 14.2 0.0 0.081 13.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain 2-Hacid_dh_C PF02826.19 KFY04858.1 - 9.2e-52 175.0 0.0 1.4e-51 174.4 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 KFY04858.1 - 5.2e-37 126.5 0.1 6.8e-37 126.1 0.1 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 KFY04858.1 - 0.00011 22.4 0.2 0.00098 19.3 0.1 2.3 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase AdoHcyase_NAD PF00670.21 KFY04858.1 - 0.0047 17.0 0.0 0.012 15.7 0.0 1.6 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain ACT PF01842.25 KFY04858.1 - 0.0061 16.3 1.1 0.023 14.5 0.2 2.5 2 1 0 2 2 2 1 ACT domain XdhC_C PF13478.6 KFY04858.1 - 0.053 14.0 0.0 0.2 12.1 0.0 1.9 2 0 0 2 2 2 0 XdhC Rossmann domain NAP PF00956.18 KFY04859.1 - 1.1e-101 339.5 10.1 1.1e-101 339.5 10.1 1.7 2 0 0 2 2 2 1 Nucleosome assembly protein (NAP) P5-ATPase PF12409.8 KFY04860.1 - 5e-42 143.0 1.9 5.3e-42 142.9 0.2 2.0 2 0 0 2 2 2 1 P5-type ATPase cation transporter E1-E2_ATPase PF00122.20 KFY04860.1 - 2.5e-27 95.6 0.0 5.6e-27 94.4 0.0 1.6 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.26 KFY04860.1 - 2.2e-13 51.0 0.1 9.1e-05 22.8 0.0 3.2 3 0 0 3 3 3 3 haloacid dehalogenase-like hydrolase Cation_ATPase_C PF00689.21 KFY04860.1 - 0.00011 21.9 6.5 0.00011 21.9 6.5 2.2 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Cation_ATPase PF13246.6 KFY04860.1 - 0.006 16.6 0.0 0.015 15.4 0.0 1.6 1 0 0 1 1 1 1 Cation transport ATPase (P-type) CBP_BcsF PF11120.8 KFY04860.1 - 0.15 12.2 0.2 0.45 10.7 0.2 1.7 1 0 0 1 1 1 0 Cellulose biosynthesis protein BcsF tRNA-synt_2b PF00587.25 KFY04861.1 - 5.7e-38 130.7 0.1 1.3e-37 129.5 0.0 1.6 2 0 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.22 KFY04861.1 - 3.5e-20 72.2 7.5 3.5e-20 72.2 7.5 2.3 3 0 0 3 3 3 1 Seryl-tRNA synthetase N-terminal domain SPT16 PF08644.11 KFY04861.1 - 0.43 10.8 3.1 0.99 9.6 3.1 1.6 1 0 0 1 1 1 0 FACT complex subunit (SPT16/CDC68) Ras PF00071.22 KFY04862.1 - 6.6e-46 155.9 1.0 7.5e-46 155.7 1.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFY04862.1 - 1.8e-16 60.4 0.1 2.8e-16 59.8 0.1 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFY04862.1 - 2.4e-08 33.6 0.0 2.6e-08 33.5 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KFY04862.1 - 6e-07 29.2 0.2 8.6e-06 25.4 0.1 2.0 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 KFY04862.1 - 0.00037 20.6 0.1 0.00055 20.0 0.1 1.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KFY04862.1 - 0.00061 19.7 0.9 0.056 13.3 0.0 2.2 1 1 1 2 2 2 2 RsgA GTPase SRPRB PF09439.10 KFY04862.1 - 0.0018 17.7 0.1 0.0035 16.8 0.1 1.5 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_28 PF13521.6 KFY04862.1 - 0.017 15.4 0.0 0.31 11.3 0.0 2.1 2 0 0 2 2 2 0 AAA domain FeoB_N PF02421.18 KFY04862.1 - 0.036 13.6 0.0 0.3 10.6 0.0 2.0 1 1 0 1 1 1 0 Ferrous iron transport protein B AAA_14 PF13173.6 KFY04862.1 - 0.037 14.1 0.0 0.059 13.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain WAPL PF07814.13 KFY04863.1 - 2.2e-68 230.7 0.0 3.3e-68 230.2 0.0 1.3 1 0 0 1 1 1 1 Wings apart-like protein regulation of heterochromatin UPRTase PF14681.6 KFY04864.1 - 1.3e-77 259.9 0.0 1.6e-77 259.6 0.0 1.0 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.27 KFY04864.1 - 0.006 16.1 0.0 0.0092 15.5 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosyl transferase domain Flu_C_NS1 PF03506.13 KFY04864.1 - 0.051 13.6 0.0 0.075 13.0 0.0 1.3 1 0 0 1 1 1 0 Influenza C non-structural protein (NS1) Elf1 PF05129.13 KFY04865.1 - 2.2e-29 101.3 2.8 3e-29 100.9 2.8 1.2 1 0 0 1 1 1 1 Transcription elongation factor Elf1 like GTP_CH_N PF12471.8 KFY04866.1 - 5.9e-89 297.0 0.0 8.8e-89 296.4 0.0 1.3 1 0 0 1 1 1 1 GTP cyclohydrolase N terminal GTP_cyclohydro2 PF00925.20 KFY04866.1 - 1.2e-16 60.7 0.0 2e-16 60.0 0.0 1.3 1 0 0 1 1 1 1 GTP cyclohydrolase II Ribosomal_S3Ae PF01015.18 KFY04868.1 - 2.3e-88 295.0 3.9 3.9e-88 294.3 3.9 1.3 1 0 0 1 1 1 1 Ribosomal S3Ae family Ras PF00071.22 KFY04868.1 - 1.1e-41 142.2 0.0 2.3e-41 141.1 0.0 1.5 1 0 0 1 1 1 1 Ras family Roc PF08477.13 KFY04868.1 - 4.6e-19 68.8 0.0 1.8e-18 66.9 0.0 2.0 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 KFY04868.1 - 7.7e-06 25.5 0.0 1.5e-05 24.5 0.0 1.5 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KFY04868.1 - 0.0048 16.4 0.0 0.012 15.2 0.0 1.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain SUI1 PF01253.22 KFY04868.1 - 0.075 13.6 0.0 0.21 12.1 0.0 1.8 1 0 0 1 1 1 0 Translation initiation factor SUI1 NEMO PF11577.8 KFY04868.1 - 0.18 11.9 0.4 1.2 9.1 0.0 2.3 2 0 0 2 2 2 0 NF-kappa-B essential modulator NEMO Abhydrolase_1 PF00561.20 KFY04869.1 - 1.3e-27 97.1 0.0 1.8e-21 77.0 0.0 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 KFY04869.1 - 1.6e-12 48.5 0.0 2e-12 48.2 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KFY04869.1 - 1.7e-11 43.8 0.0 2.6e-11 43.3 0.0 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Thioesterase PF00975.20 KFY04869.1 - 5.7e-06 26.6 0.0 6.7e-06 26.4 0.0 1.2 1 0 0 1 1 1 1 Thioesterase domain PGAP1 PF07819.13 KFY04869.1 - 0.00018 21.3 0.1 0.0013 18.5 0.1 2.0 1 1 0 1 1 1 1 PGAP1-like protein Ndr PF03096.14 KFY04869.1 - 0.00019 20.3 0.0 0.00024 19.9 0.0 1.4 1 1 0 1 1 1 1 Ndr family Esterase PF00756.20 KFY04869.1 - 0.0013 18.5 0.0 0.0016 18.1 0.0 1.2 1 0 0 1 1 1 1 Putative esterase Chlorophyllase PF07224.11 KFY04869.1 - 0.0032 16.5 0.0 0.0046 16.0 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase Ser_hydrolase PF06821.13 KFY04869.1 - 0.019 14.9 0.0 0.026 14.4 0.0 1.3 1 0 0 1 1 1 0 Serine hydrolase Chlorophyllase2 PF12740.7 KFY04869.1 - 0.03 13.2 0.0 0.045 12.7 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase enzyme Lipase_3 PF01764.25 KFY04869.1 - 0.099 12.5 0.0 0.17 11.7 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) DUF2974 PF11187.8 KFY04869.1 - 0.14 11.7 0.0 0.2 11.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) tRNA-synt_1b PF00579.25 KFY04870.1 - 1.8e-67 227.7 0.0 2.6e-67 227.2 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) Ribosomal_S10 PF00338.22 KFY04870.1 - 5.2e-26 90.7 0.0 1.3e-25 89.5 0.0 1.7 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e Fcf2 PF08698.11 KFY04871.1 - 7e-37 125.7 1.0 1.6e-36 124.5 0.2 1.9 1 1 1 2 2 2 1 Fcf2 pre-rRNA processing TGF_beta_GS PF08515.12 KFY04871.1 - 0.2 11.2 5.8 0.51 9.9 5.8 1.6 1 0 0 1 1 1 0 Transforming growth factor beta type I GS-motif CBFD_NFYB_HMF PF00808.23 KFY04872.1 - 2.7e-19 69.2 0.5 4.6e-19 68.5 0.5 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 KFY04872.1 - 1e-14 55.0 0.3 1e-14 55.0 0.3 2.0 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 CENP-X PF09415.10 KFY04872.1 - 0.055 13.8 0.1 0.094 13.0 0.1 1.4 1 0 0 1 1 1 0 CENP-S associating Centromere protein X Sec15 PF04091.12 KFY04873.1 - 4.6e-116 387.7 0.3 4.6e-116 387.7 0.3 1.9 2 1 0 2 2 2 1 Exocyst complex subunit Sec15-like Sec8_exocyst PF04048.14 KFY04873.1 - 8.7e-05 22.4 5.1 8.7e-05 22.4 5.1 2.7 2 0 0 2 2 2 1 Sec8 exocyst complex component specific domain COG2 PF06148.11 KFY04873.1 - 0.00028 21.0 6.0 0.00028 21.0 6.0 3.4 3 1 0 3 3 3 1 COG (conserved oligomeric Golgi) complex component, COG2 COG5 PF10392.9 KFY04873.1 - 0.0037 17.4 7.1 0.01 16.0 5.4 2.6 2 0 0 2 2 2 1 Golgi transport complex subunit 5 Vps51 PF08700.11 KFY04873.1 - 0.056 13.5 4.5 0.18 11.9 1.7 3.1 2 0 0 2 2 2 0 Vps51/Vps67 Mre11_DNA_bind PF04152.14 KFY04873.1 - 0.074 13.4 1.1 0.75 10.1 0.0 2.9 3 0 0 3 3 3 0 Mre11 DNA-binding presumed domain DUF1400 PF07176.11 KFY04873.1 - 0.093 13.0 3.6 1.7 8.9 0.1 3.5 4 0 0 4 4 4 0 Alpha/beta hydrolase of unknown function (DUF1400) Vps54_N PF10475.9 KFY04873.1 - 0.44 9.8 12.1 0.099 11.9 8.0 1.9 2 0 0 2 2 2 0 Vacuolar-sorting protein 54, of GARP complex Sec5 PF15469.6 KFY04873.1 - 1.1 9.0 9.2 0.69 9.7 3.9 2.7 2 1 0 2 2 2 0 Exocyst complex component Sec5 DUF3510 PF12022.8 KFY04873.1 - 7.1 7.0 8.2 16 5.9 0.1 4.2 3 2 1 4 4 4 0 Domain of unknown function (DUF3510) RRM_2 PF04059.12 KFY04874.1 - 4.8e-40 135.7 0.3 8.6e-40 134.9 0.3 1.4 1 0 0 1 1 1 1 RNA recognition motif 2 RRM_1 PF00076.22 KFY04874.1 - 4.2e-05 23.3 0.0 0.077 12.8 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Xpo1 PF08389.12 KFY04875.1 - 0.00099 19.2 0.2 0.02 15.0 0.0 2.9 2 0 0 2 2 2 1 Exportin 1-like protein FUN14 PF04930.15 KFY04876.1 - 1.6e-07 31.6 0.8 3.4e-07 30.6 0.8 1.5 1 0 0 1 1 1 1 FUN14 family Sad1_UNC PF07738.13 KFY04877.1 - 7.2e-34 116.6 0.0 1.1e-33 116.0 0.0 1.3 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal Peptidase_S64 PF08192.11 KFY04877.1 - 0.078 11.5 8.1 0.012 14.2 4.1 1.5 2 0 0 2 2 2 0 Peptidase family S64 DASH_Ask1 PF08655.10 KFY04877.1 - 0.15 12.0 0.1 5.1 7.1 0.1 2.4 1 1 0 1 1 1 0 DASH complex subunit Ask1 ABC_membrane PF00664.23 KFY04882.1 - 1.2e-90 304.0 26.8 1.8e-47 162.3 5.8 2.4 2 1 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 KFY04882.1 - 2.8e-62 209.3 0.0 4.6e-31 108.2 0.0 2.5 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 KFY04882.1 - 3.3e-15 56.1 2.7 0.00039 19.9 0.0 4.5 4 0 0 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 KFY04882.1 - 3.4e-09 37.3 1.9 0.0033 17.8 0.3 3.3 2 2 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.6 KFY04882.1 - 2.5e-08 33.5 1.5 0.0013 18.4 0.0 3.1 3 0 0 3 3 2 2 P-loop containing region of AAA domain AAA_22 PF13401.6 KFY04882.1 - 3.2e-08 33.9 0.6 0.15 12.3 0.1 4.2 2 2 0 2 2 2 2 AAA domain DUF87 PF01935.17 KFY04882.1 - 4.8e-08 33.4 1.0 0.00012 22.2 0.2 2.4 2 0 0 2 2 2 2 Helicase HerA, central domain AAA_30 PF13604.6 KFY04882.1 - 4.5e-06 26.5 2.8 0.034 13.9 0.0 3.9 3 1 0 3 3 3 2 AAA domain RsgA_GTPase PF03193.16 KFY04882.1 - 4.7e-05 23.4 0.0 0.069 13.1 0.0 2.7 2 0 0 2 2 2 2 RsgA GTPase AAA_23 PF13476.6 KFY04882.1 - 0.00011 22.7 0.3 0.14 12.6 0.1 2.5 2 0 0 2 2 2 2 AAA domain ABC_ATPase PF09818.9 KFY04882.1 - 0.00046 19.1 0.3 0.14 11.0 0.0 2.7 3 0 0 3 3 3 1 Predicted ATPase of the ABC class AAA_21 PF13304.6 KFY04882.1 - 0.00049 20.0 3.0 0.14 11.9 0.0 3.7 3 1 0 4 4 4 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA PF00004.29 KFY04882.1 - 0.00095 19.6 1.0 7.6 7.0 0.2 3.9 3 1 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.6 KFY04882.1 - 0.0019 17.8 0.3 1.7 8.2 0.0 3.8 4 0 0 4 4 4 1 AAA domain AAA_18 PF13238.6 KFY04882.1 - 0.0021 18.6 0.0 3.1 8.3 0.0 2.8 2 0 0 2 2 2 1 AAA domain DUF3987 PF13148.6 KFY04882.1 - 0.0033 16.5 0.0 0.35 9.8 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF3987) AAA_33 PF13671.6 KFY04882.1 - 0.0035 17.5 0.3 2.7 8.2 0.1 2.8 2 0 0 2 2 2 1 AAA domain AAA_15 PF13175.6 KFY04882.1 - 0.0052 16.5 0.1 0.55 9.9 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain APS_kinase PF01583.20 KFY04882.1 - 0.011 15.6 0.1 3.5 7.5 0.0 2.4 2 0 0 2 2 2 0 Adenylylsulphate kinase PRK PF00485.18 KFY04882.1 - 0.012 15.4 0.9 19 5.0 0.0 3.3 3 0 0 3 3 3 0 Phosphoribulokinase / Uridine kinase family Zeta_toxin PF06414.12 KFY04882.1 - 0.019 14.3 0.0 2 7.6 0.0 2.5 2 0 0 2 2 2 0 Zeta toxin SbcCD_C PF13558.6 KFY04882.1 - 0.023 14.9 1.1 4.4 7.6 0.0 3.4 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_5 PF07728.14 KFY04882.1 - 0.025 14.6 0.0 5.8 6.9 0.0 2.9 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) MMR_HSR1 PF01926.23 KFY04882.1 - 0.03 14.4 0.1 6.5 6.9 0.0 2.7 2 0 0 2 2 2 0 50S ribosome-binding GTPase DEAD PF00270.29 KFY04882.1 - 0.045 13.5 0.1 2 8.1 0.0 3.0 3 1 0 3 3 3 0 DEAD/DEAH box helicase NB-ARC PF00931.22 KFY04882.1 - 0.046 12.9 0.0 12 5.0 0.0 2.8 3 0 0 3 3 3 0 NB-ARC domain SRP54 PF00448.22 KFY04882.1 - 0.049 13.3 0.2 12 5.4 0.0 2.8 3 0 0 3 3 3 0 SRP54-type protein, GTPase domain AAA_7 PF12775.7 KFY04882.1 - 0.072 12.6 0.1 13 5.2 0.0 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region G-alpha PF00503.20 KFY04882.1 - 0.12 11.5 0.0 13 4.8 0.0 2.2 2 0 0 2 2 2 0 G-protein alpha subunit FtsK_SpoIIIE PF01580.18 KFY04882.1 - 0.13 11.6 0.1 0.59 9.4 0.0 2.1 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_24 PF13479.6 KFY04882.1 - 0.18 11.5 0.3 12 5.6 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.6 KFY04882.1 - 0.23 11.9 0.6 27 5.2 0.1 2.7 2 0 0 2 2 2 0 AAA domain Cad PF03596.13 KFY04882.1 - 0.3 11.0 3.8 0.28 11.1 0.3 2.6 2 0 0 2 2 2 0 Cadmium resistance transporter Acetyltransf_8 PF13523.6 KFY04883.1 - 2.1e-41 141.0 0.1 2.9e-41 140.5 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain ECH_1 PF00378.20 KFY04884.1 - 7.1e-54 182.8 0.0 9.6e-54 182.3 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KFY04884.1 - 6.6e-30 104.7 1.0 1.3e-25 90.6 0.3 2.6 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase MFS_1 PF07690.16 KFY04885.1 - 3.8e-23 82.0 56.2 2.6e-15 56.2 32.6 2.5 2 1 1 3 3 3 2 Major Facilitator Superfamily TRI12 PF06609.13 KFY04885.1 - 4.7e-09 35.2 29.2 6.8e-09 34.7 28.7 1.4 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) AMP-binding PF00501.28 KFY04886.1 - 4.1e-70 236.5 0.0 3e-65 220.5 0.0 2.3 2 0 0 2 2 2 2 AMP-binding enzyme Condensation PF00668.20 KFY04886.1 - 3e-68 230.6 0.0 4.7e-37 127.7 0.0 3.1 3 0 0 3 3 3 2 Condensation domain PP-binding PF00550.25 KFY04886.1 - 2.6e-24 85.4 0.0 7.8e-12 45.4 0.0 2.9 2 0 0 2 2 2 2 Phosphopantetheine attachment site AMP-binding_C PF13193.6 KFY04886.1 - 0.0036 18.3 0.0 5.7 8.0 0.0 3.0 2 0 0 2 2 2 2 AMP-binding enzyme C-terminal domain DUF1749 PF08538.10 KFY04887.1 - 2e-98 329.2 0.0 2.5e-98 328.9 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1749) Abhydrolase_1 PF00561.20 KFY04887.1 - 0.0012 18.6 0.1 0.0021 17.8 0.1 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold PGAP1 PF07819.13 KFY04887.1 - 0.0013 18.5 0.0 0.0022 17.8 0.0 1.4 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_6 PF12697.7 KFY04887.1 - 0.0013 19.4 0.0 0.0026 18.4 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KFY04887.1 - 0.039 13.2 0.0 0.092 12.0 0.0 1.7 2 0 0 2 2 2 0 Serine aminopeptidase, S33 Hepar_II_III PF07940.13 KFY04888.1 - 2e-10 40.7 0.0 3.1e-10 40.1 0.0 1.3 1 0 0 1 1 1 1 Heparinase II/III-like protein Fungal_trans PF04082.18 KFY04889.1 - 3.5e-15 55.8 0.1 1e-14 54.3 0.1 1.8 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KFY04889.1 - 2.1e-06 27.7 10.9 3.6e-06 27.0 10.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF2264 PF10022.9 KFY04890.1 - 1.8e-126 422.0 0.1 2.2e-126 421.7 0.1 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2264) Glyco_hydro_88 PF07470.13 KFY04891.1 - 8.7e-10 38.2 0.2 1.7e-09 37.2 0.2 1.4 1 0 0 1 1 1 1 Glycosyl Hydrolase Family 88 Sugar_tr PF00083.24 KFY04892.1 - 6.8e-79 265.8 21.5 7.8e-79 265.6 21.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KFY04892.1 - 5.4e-38 130.8 49.6 2e-31 109.2 23.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 KFY04892.1 - 0.00033 19.2 0.5 0.00068 18.2 0.5 1.5 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF2463 PF09591.10 KFY04892.1 - 0.014 15.2 0.4 2.9 7.7 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2463) COesterase PF00135.28 KFY04893.1 - 1.7e-84 284.5 0.0 2e-84 284.3 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 KFY04893.1 - 4.1e-07 30.1 0.0 1.6e-06 28.1 0.0 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 KFY04893.1 - 0.0064 16.0 0.1 0.0093 15.5 0.1 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family Sulfakinin PF08257.11 KFY04893.1 - 0.23 11.6 0.9 0.65 10.2 0.9 1.8 1 0 0 1 1 1 0 Sulfakinin family Glyco_hydro_28 PF00295.17 KFY04894.1 - 1.6e-35 122.7 9.9 2.2e-35 122.2 9.9 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 Beta_helix PF13229.6 KFY04894.1 - 1.4 8.8 20.8 0.027 14.3 12.3 2.4 2 1 0 3 3 3 0 Right handed beta helix region Zn_clus PF00172.18 KFY04895.1 - 4.8e-09 36.2 10.1 8.4e-09 35.4 10.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 KFY04895.1 - 1.2e-06 27.6 0.1 1.7e-06 27.1 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Peroxidase_2 PF01328.17 KFY04896.1 - 2.8e-48 164.9 0.0 3.7e-48 164.5 0.0 1.1 1 0 0 1 1 1 1 Peroxidase, family 2 Mto2_bdg PF12808.7 KFY04899.1 - 0.097 13.0 0.1 0.23 11.8 0.1 1.7 1 0 0 1 1 1 0 Micro-tubular organiser Mto1 C-term Mto2-binding region DUF4633 PF15464.6 KFY04899.1 - 0.11 12.7 1.0 6.2 7.0 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4633) FA_hydroxylase PF04116.13 KFY04902.1 - 3.2e-26 92.2 16.9 3.2e-26 92.2 16.9 2.5 2 1 1 3 3 3 1 Fatty acid hydroxylase superfamily NCA2 PF08637.10 KFY04903.1 - 2.8e-112 374.6 0.0 4e-112 374.1 0.0 1.2 1 0 0 1 1 1 1 ATP synthase regulation protein NCA2 Pyridoxal_deC PF00282.19 KFY04903.1 - 9.5e-78 261.5 0.0 1.3e-77 261.1 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.19 KFY04903.1 - 6.2e-08 32.0 0.0 1.2e-07 31.1 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 KFY04903.1 - 9.3e-08 31.7 0.0 1.5e-07 31.0 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase HEM4 PF02602.15 KFY04903.1 - 0.074 12.4 0.0 0.16 11.3 0.0 1.5 1 0 0 1 1 1 0 Uroporphyrinogen-III synthase HemD ADH_N PF08240.12 KFY04909.1 - 3.2e-29 101.0 0.4 5e-29 100.4 0.4 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 KFY04909.1 - 1.8e-14 53.8 0.0 3.4e-14 52.9 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 KFY04909.1 - 5.4e-05 22.8 0.0 8.4e-05 22.1 0.0 1.4 1 1 0 1 1 1 1 Glucose dehydrogenase C-terminus ADH_N_assoc PF13823.6 KFY04909.1 - 0.0052 16.7 0.1 0.0098 15.8 0.1 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-associated AlaDh_PNT_C PF01262.21 KFY04909.1 - 0.097 12.0 0.0 0.16 11.2 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain AMP-binding PF00501.28 KFY04910.1 - 9.2e-92 307.8 0.0 1.1e-91 307.6 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 KFY04910.1 - 5e-14 53.0 0.1 2.5e-13 50.8 0.0 2.1 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain Fungal_trans PF04082.18 KFY04911.1 - 9.6e-16 57.6 1.7 1.4e-15 57.1 1.7 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain ECH_1 PF00378.20 KFY04912.1 - 3.9e-38 131.2 0.0 1.9e-25 89.6 0.0 2.1 2 0 0 2 2 2 2 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 KFY04912.1 - 1.1e-18 67.9 0.0 3.1e-09 36.8 0.0 3.0 2 1 1 3 3 3 3 Enoyl-CoA hydratase/isomerase NMO PF03060.15 KFY04913.1 - 1.7e-54 185.5 1.4 2.2e-54 185.1 1.4 1.2 1 0 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.25 KFY04913.1 - 1.5e-07 30.7 1.2 5.4e-06 25.6 1.2 2.3 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.18 KFY04913.1 - 0.0016 17.5 2.6 0.0035 16.4 2.6 1.5 1 0 0 1 1 1 1 FMN-dependent dehydrogenase MFS_1 PF07690.16 KFY04914.1 - 9.7e-31 107.0 33.5 9.7e-31 107.0 33.5 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily TLP1_add_C PF18313.1 KFY04915.1 - 1.5e-19 69.7 0.0 3e-19 68.7 0.0 1.5 1 0 0 1 1 1 1 Thiolase-like protein type 1 additional C-terminal domain Thiolase_C PF02803.18 KFY04915.1 - 0.083 12.6 0.0 0.2 11.3 0.0 1.6 1 0 0 1 1 1 0 Thiolase, C-terminal domain AMP-binding PF00501.28 KFY04916.1 - 8.7e-77 258.5 0.0 1.5e-76 257.7 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme Fungal_trans PF04082.18 KFY04916.1 - 8.3e-21 74.2 0.0 1.7e-20 73.1 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain AMP-binding_C PF13193.6 KFY04916.1 - 1.6e-12 48.2 0.3 3.9e-12 47.0 0.3 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain FMO-like PF00743.19 KFY04916.1 - 4e-12 45.3 0.1 1e-10 40.7 0.0 2.3 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.6 KFY04916.1 - 3.7e-11 43.1 0.0 1.1e-10 41.6 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 KFY04916.1 - 3.5e-10 39.6 0.0 4.4e-09 36.0 0.0 2.6 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Zn_clus PF00172.18 KFY04916.1 - 4.2e-09 36.4 11.7 8.5e-09 35.4 11.7 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pyr_redox_2 PF07992.14 KFY04916.1 - 1.6e-08 34.2 0.0 1.7e-07 30.7 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lactamase_B PF00753.27 KFY04916.1 - 3.4e-07 30.5 0.2 6.4e-07 29.6 0.2 1.5 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily DAO PF01266.24 KFY04916.1 - 0.00017 21.3 0.0 0.0026 17.4 0.0 2.6 2 0 0 2 2 2 1 FAD dependent oxidoreductase K_oxygenase PF13434.6 KFY04916.1 - 0.00041 19.6 0.0 0.085 12.0 0.0 3.0 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.6 KFY04916.1 - 0.0015 18.5 0.0 0.01 15.8 0.0 2.4 2 0 0 2 2 2 1 FAD-NAD(P)-binding Thi4 PF01946.17 KFY04916.1 - 0.01 15.1 0.0 0.019 14.2 0.0 1.3 1 0 0 1 1 1 0 Thi4 family Amino_oxidase PF01593.24 KFY04916.1 - 0.013 14.8 0.0 0.21 10.8 0.0 2.6 3 0 0 3 3 3 0 Flavin containing amine oxidoreductase Lactamase_B_2 PF12706.7 KFY04916.1 - 0.047 13.2 0.0 0.13 11.7 0.0 1.7 1 0 0 1 1 1 0 Beta-lactamase superfamily domain Pyr_redox PF00070.27 KFY04916.1 - 0.2 12.2 0.0 1.2 9.8 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Aldedh PF00171.22 KFY04917.1 - 1.9e-160 534.4 0.2 2.2e-160 534.2 0.2 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Recep_L_domain PF01030.24 KFY04918.1 - 0.015 15.4 0.0 3.2 7.9 0.0 3.8 2 1 1 4 4 4 0 Receptor L domain Comm PF15957.5 KFY04918.1 - 0.056 13.8 0.1 0.11 12.8 0.1 1.4 1 0 0 1 1 1 0 Commissureless Pec_lyase_C PF00544.19 KFY04919.1 - 4.4e-24 85.2 8.9 4.3e-23 82.0 8.9 2.1 1 1 0 1 1 1 1 Pectate lyase Beta_helix PF13229.6 KFY04919.1 - 0.00012 22.0 16.1 0.00016 21.6 10.5 2.1 1 1 1 2 2 2 2 Right handed beta helix region TFB6 PF17110.5 KFY04922.1 - 0.072 12.8 2.9 0.095 12.4 2.9 1.2 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH KfrA_N PF11740.8 KFY04922.1 - 1.3 9.7 8.6 2.1 9.0 8.6 1.3 1 0 0 1 1 1 0 Plasmid replication region DNA-binding N-term DUF5633 PF18656.1 KFY04922.1 - 9.9 6.1 10.7 8.2 6.4 0.0 2.9 3 0 0 3 3 3 0 Family of unknown function (DUF5633) tRNA-synt_2 PF00152.20 KFY04923.1 - 2.1e-70 237.3 0.0 2.9e-70 236.9 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 KFY04923.1 - 0.0018 18.2 0.1 0.0042 17.0 0.1 1.6 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain DUF883 PF05957.13 KFY04923.1 - 0.41 11.3 3.1 1.3 9.6 3.1 1.8 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF883) MCM_N PF14551.6 KFY04923.1 - 0.41 11.2 2.1 0.51 11.0 0.0 2.3 2 1 0 2 2 2 0 MCM N-terminal domain DUF3847 PF12958.7 KFY04923.1 - 4.7 7.4 8.1 13 6.0 8.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3847) DUF4315 PF14193.6 KFY04923.1 - 5.4 7.1 10.7 12 6.0 10.7 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4315) SDA1 PF05285.12 KFY04924.1 - 3 7.2 16.2 3.1 7.1 16.2 1.1 1 0 0 1 1 1 0 SDA1 zf-BED PF02892.15 KFY04925.1 - 0.049 13.7 0.8 0.084 12.9 0.8 1.3 1 0 0 1 1 1 0 BED zinc finger PAC1 PF16094.5 KFY04927.1 - 0.93 8.6 5.1 1 8.5 5.1 1.0 1 0 0 1 1 1 0 Proteasome assembly chaperone 4 CDC45 PF02724.14 KFY04927.1 - 3 6.0 6.7 3.1 6.0 6.7 1.0 1 0 0 1 1 1 0 CDC45-like protein DNA_ligase_A_M PF01068.21 KFY04928.1 - 4.9e-60 202.7 0.2 3.2e-47 160.8 0.0 2.3 2 0 0 2 2 2 2 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.14 KFY04928.1 - 5e-43 147.4 0.0 9.4e-43 146.5 0.0 1.5 1 0 0 1 1 1 1 DNA ligase N terminus DNA_ligase_A_C PF04679.15 KFY04928.1 - 2.4e-28 98.6 0.0 1.1e-27 96.5 0.0 2.2 1 0 0 1 1 1 1 ATP dependent DNA ligase C terminal region RNA_ligase PF09414.10 KFY04928.1 - 1.7e-05 25.2 0.1 2.9e-05 24.4 0.1 1.4 1 0 0 1 1 1 1 RNA ligase PNKP_ligase PF16542.5 KFY04928.1 - 0.02 14.4 0.0 0.038 13.5 0.0 1.4 1 0 0 1 1 1 0 PNKP adenylyltransferase domain, ligase domain tRNA-synt_2 PF00152.20 KFY04929.1 - 1.1e-85 287.5 0.0 1.6e-85 286.9 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 KFY04929.1 - 8.3e-09 35.3 0.0 1.5e-08 34.5 0.0 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA_anti_2 PF13742.6 KFY04929.1 - 0.057 13.6 0.0 0.18 12.0 0.0 1.8 1 0 0 1 1 1 0 OB-fold nucleic acid binding domain GMC_oxred_N PF00732.19 KFY04931.1 - 1e-62 212.2 0.0 1.3e-62 211.9 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 KFY04931.1 - 2.5e-37 128.6 0.0 4.3e-37 127.8 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.12 KFY04931.1 - 4.8e-05 22.6 0.1 0.00014 21.0 0.0 1.8 2 0 0 2 2 2 1 Lycopene cyclase protein FAD_binding_2 PF00890.24 KFY04931.1 - 0.00038 19.6 0.1 0.0025 16.9 0.0 2.0 2 0 0 2 2 2 1 FAD binding domain Thi4 PF01946.17 KFY04931.1 - 0.00048 19.4 0.1 0.001 18.4 0.1 1.4 1 0 0 1 1 1 1 Thi4 family NAD_binding_8 PF13450.6 KFY04931.1 - 0.0017 18.5 1.5 0.0045 17.2 0.0 2.6 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KFY04931.1 - 0.002 17.4 0.1 0.0036 16.6 0.1 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KFY04931.1 - 0.004 16.8 0.1 0.01 15.5 0.0 1.6 2 0 0 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.14 KFY04931.1 - 0.0072 15.1 0.2 0.32 9.6 0.1 2.3 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox_3 PF13738.6 KFY04931.1 - 0.012 14.9 0.0 0.063 12.5 0.0 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.18 KFY04931.1 - 0.11 12.7 0.1 0.4 11.0 0.1 2.0 2 0 0 2 2 2 0 TrkA-N domain DUF3328 PF11807.8 KFY04932.1 - 1.8e-52 178.3 0.0 2.2e-52 178.0 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) adh_short PF00106.25 KFY04933.1 - 5e-09 35.9 0.0 1.1e-08 34.8 0.0 1.5 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.10 KFY04933.1 - 0.0024 17.8 0.0 0.0038 17.2 0.0 1.2 1 0 0 1 1 1 1 KR domain Sacchrp_dh_NADP PF03435.18 KFY04933.1 - 0.1 12.9 0.0 0.16 12.2 0.0 1.3 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Arb2 PF09757.9 KFY04934.1 - 4.6e-93 311.1 0.0 6.2e-93 310.7 0.0 1.2 1 0 0 1 1 1 1 Arb2 domain Hist_deacetyl PF00850.19 KFY04934.1 - 2e-82 277.1 0.0 3.1e-82 276.5 0.0 1.3 1 0 0 1 1 1 1 Histone deacetylase domain Glyco_hydro_61 PF03443.14 KFY04935.1 - 3.1e-54 184.0 0.2 4.4e-54 183.5 0.2 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 CBM_1 PF00734.18 KFY04935.1 - 1.9e-12 46.9 12.1 1.9e-12 46.9 12.1 2.0 2 0 0 2 2 2 1 Fungal cellulose binding domain Glyco_hydro_61 PF03443.14 KFY04936.1 - 1.6e-66 224.2 0.1 1.9e-66 223.9 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 NACHT_N PF17100.5 KFY04937.1 - 1.3e-23 84.1 0.4 3.8e-23 82.5 0.4 1.8 1 0 0 1 1 1 1 N-terminal domain of NWD NACHT-NTPase Ank_2 PF12796.7 KFY04937.1 - 5e-19 68.7 0.4 3.8e-07 30.6 0.1 3.6 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KFY04937.1 - 3e-15 56.3 1.3 5.4e-08 33.2 0.3 5.0 3 1 2 5 5 5 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 KFY04937.1 - 2.7e-14 53.1 1.2 5.8e-08 32.8 0.1 3.8 4 0 0 4 4 4 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFY04937.1 - 6.3e-11 41.5 0.4 0.00043 20.5 0.0 4.6 5 0 0 5 5 5 2 Ankyrin repeat Ank PF00023.30 KFY04937.1 - 5.8e-08 32.8 0.6 0.0011 19.3 0.0 3.2 2 0 0 2 2 2 2 Ankyrin repeat NACHT PF05729.12 KFY04937.1 - 3.7e-05 23.7 0.1 0.00026 21.0 0.1 2.3 1 1 0 1 1 1 1 NACHT domain TPR_12 PF13424.6 KFY04937.1 - 0.00021 21.5 13.8 0.061 13.6 0.2 4.7 5 1 0 5 5 4 3 Tetratricopeptide repeat AAA_22 PF13401.6 KFY04937.1 - 0.00029 21.1 0.0 0.0065 16.7 0.0 3.0 1 1 1 2 2 2 1 AAA domain AAA_16 PF13191.6 KFY04937.1 - 0.0059 17.0 0.0 0.021 15.2 0.0 1.9 1 0 0 1 1 1 1 AAA ATPase domain MARVEL PF01284.23 KFY04937.1 - 0.0079 16.2 1.5 0.016 15.3 1.5 1.4 1 0 0 1 1 1 1 Membrane-associating domain TPR_2 PF07719.17 KFY04937.1 - 0.0099 15.9 0.1 54 4.2 0.0 4.8 4 0 0 4 4 4 0 Tetratricopeptide repeat AAA PF00004.29 KFY04937.1 - 0.13 12.7 0.0 0.58 10.6 0.0 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) CDC45 PF02724.14 KFY04937.1 - 6.9 4.8 12.2 13 3.9 12.2 1.3 1 0 0 1 1 1 0 CDC45-like protein UPF0061 PF02696.14 KFY04939.1 - 7.4e-128 427.2 0.0 1.6e-111 373.4 0.0 2.6 2 1 1 3 3 3 2 Uncharacterized ACR, YdiU/UPF0061 family SesA PF17107.5 KFY04939.1 - 3.3e-33 114.5 0.6 1.2e-32 112.6 0.6 2.1 1 0 0 1 1 1 1 N-terminal domain on NACHT_NTPase and P-loop NTPases Ank_2 PF12796.7 KFY04939.1 - 2.3e-16 60.2 0.7 1.4e-09 38.4 1.1 3.5 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KFY04939.1 - 1.5e-12 46.5 1.4 0.044 14.3 0.0 5.7 5 0 0 5 5 5 3 Ankyrin repeat Ank_5 PF13857.6 KFY04939.1 - 9.1e-10 38.6 0.1 0.026 14.8 0.0 4.3 4 0 0 4 4 4 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 KFY04939.1 - 3.8e-09 36.9 0.4 1e-05 26.0 0.0 3.4 4 0 0 4 4 2 2 Ankyrin repeats (many copies) Ank PF00023.30 KFY04939.1 - 1.2e-08 35.0 2.1 0.12 12.8 0.0 5.6 5 0 0 5 5 5 2 Ankyrin repeat NACHT PF05729.12 KFY04939.1 - 0.0061 16.5 0.0 0.026 14.5 0.0 2.1 2 0 0 2 2 2 1 NACHT domain Ploopntkinase3 PF18751.1 KFY04939.1 - 0.012 15.5 0.0 0.039 13.9 0.0 1.9 2 0 0 2 2 1 0 P-loop Nucleotide Kinase3 AAA_22 PF13401.6 KFY04939.1 - 0.022 15.0 0.0 0.13 12.5 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 KFY04939.1 - 0.055 13.6 0.0 0.21 11.8 0.0 2.0 2 0 0 2 2 1 0 AAA domain ABC_tran PF00005.27 KFY04939.1 - 0.056 14.0 0.0 0.21 12.1 0.0 1.9 1 0 0 1 1 1 0 ABC transporter AAA_16 PF13191.6 KFY04939.1 - 0.062 13.7 0.0 0.38 11.1 0.0 2.4 1 0 0 1 1 1 0 AAA ATPase domain AAA_18 PF13238.6 KFY04939.1 - 0.086 13.4 0.0 2 9.0 0.0 3.0 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.23 KFY04939.1 - 0.1 12.7 0.0 0.47 10.5 0.0 2.1 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_30 PF13604.6 KFY04939.1 - 0.12 12.1 0.0 0.24 11.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain Com_YlbF PF06133.11 KFY04939.1 - 2.2 8.9 4.4 3.5 8.3 0.0 3.3 3 0 0 3 3 3 0 Control of competence regulator ComK, YlbF/YmcA Aldo_ket_red PF00248.21 KFY04940.1 - 2.9e-46 158.0 0.0 4.6e-45 154.1 0.0 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family B12-binding PF02310.19 KFY04940.1 - 0.015 15.3 0.0 0.026 14.5 0.0 1.3 1 0 0 1 1 1 0 B12 binding domain GFA PF04828.14 KFY04942.1 - 1.1e-22 80.2 0.0 1.5e-22 79.8 0.0 1.2 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme Auto_anti-p27 PF06677.12 KFY04942.1 - 0.71 10.1 4.3 0.91 9.7 0.0 2.3 2 0 0 2 2 2 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) ACBP PF00887.19 KFY04943.1 - 1.5e-24 86.0 0.0 6.5e-24 84.0 0.0 2.0 2 0 0 2 2 2 1 Acyl CoA binding protein PRT_C PF08372.10 KFY04943.1 - 0.036 13.8 0.0 0.056 13.2 0.0 1.3 1 0 0 1 1 1 0 Plant phosphoribosyltransferase C-terminal SAPS PF04499.15 KFY04943.1 - 0.13 11.0 0.1 0.16 10.7 0.1 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein WLM PF08325.10 KFY04944.1 - 1.1e-49 169.2 0.0 1.7e-49 168.5 0.0 1.3 1 0 0 1 1 1 1 WLM domain DUF45 PF01863.17 KFY04944.1 - 0.014 15.4 2.5 0.016 15.3 1.0 1.7 2 0 0 2 2 2 0 Protein of unknown function DUF45 SprT-like PF10263.9 KFY04944.1 - 0.035 14.0 0.0 0.071 13.0 0.0 1.7 1 0 0 1 1 1 0 SprT-like family DUF5323 PF17257.2 KFY04944.1 - 0.17 11.8 0.9 0.35 10.8 0.9 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5323) F-box-like PF12937.7 KFY04945.1 - 1.8e-05 24.6 1.5 2.2e-05 24.2 0.2 1.9 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 KFY04945.1 - 0.074 13.0 0.0 0.16 11.9 0.0 1.5 1 0 0 1 1 1 0 F-box domain F-box_4 PF15966.5 KFY04945.1 - 0.076 12.9 0.0 0.14 12.1 0.0 1.4 1 0 0 1 1 1 0 F-box Chromo PF00385.24 KFY04946.1 - 7.5e-10 38.6 0.4 1.4e-09 37.7 0.4 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Mago-bind PF09282.10 KFY04946.1 - 3.7e-05 23.5 0.5 9.4e-05 22.2 0.5 1.8 1 0 0 1 1 1 1 Mago binding TIP49 PF06068.13 KFY04947.1 - 2.6e-153 510.3 2.4 3.3e-153 510.0 2.4 1.1 1 0 0 1 1 1 1 TIP49 P-loop domain TIP49_C PF17856.1 KFY04947.1 - 1.1e-20 73.5 1.0 3.5e-20 71.9 0.2 2.4 3 0 0 3 3 2 1 TIP49 AAA-lid domain RuvB_N PF05496.12 KFY04947.1 - 5.6e-09 35.9 0.3 0.00015 21.6 0.0 2.8 3 0 0 3 3 3 2 Holliday junction DNA helicase RuvB P-loop domain AAA PF00004.29 KFY04947.1 - 1.8e-08 34.9 0.2 0.00014 22.3 0.0 2.7 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) DnaB_C PF03796.15 KFY04947.1 - 6.9e-07 28.9 1.1 1.4e-06 27.8 1.1 1.5 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain AAA_16 PF13191.6 KFY04947.1 - 2.5e-05 24.7 0.2 7.7e-05 23.1 0.2 1.9 1 1 0 1 1 1 1 AAA ATPase domain Mg_chelatase PF01078.21 KFY04947.1 - 0.00013 21.4 0.9 0.0043 16.5 0.4 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_22 PF13401.6 KFY04947.1 - 0.0022 18.3 0.0 0.29 11.4 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.14 KFY04947.1 - 0.0024 17.9 0.7 1 9.3 0.0 3.4 2 1 1 3 3 3 1 AAA domain (dynein-related subfamily) AAA_19 PF13245.6 KFY04947.1 - 0.017 15.5 2.6 0.45 10.8 2.6 2.5 1 1 0 1 1 1 0 AAA domain Sigma54_activat PF00158.26 KFY04947.1 - 0.027 14.2 0.0 6.6 6.4 0.0 2.5 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_25 PF13481.6 KFY04947.1 - 0.077 12.6 0.1 0.2 11.2 0.1 1.7 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.6 KFY04947.1 - 0.08 12.7 2.5 0.84 9.4 2.5 2.2 1 1 0 1 1 1 0 AAA domain AAA_33 PF13671.6 KFY04947.1 - 0.11 12.6 0.0 0.25 11.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain Sugarporin_N PF11471.8 KFY04948.1 - 0.015 15.3 0.1 0.015 15.3 0.1 3.9 4 0 0 4 4 4 0 Maltoporin periplasmic N-terminal extension DUF1664 PF07889.12 KFY04948.1 - 0.018 15.1 34.7 0.11 12.5 2.3 6.9 6 2 2 8 8 8 0 Protein of unknown function (DUF1664) YojJ PF10372.9 KFY04948.1 - 0.084 13.0 7.9 2.1 8.5 0.0 5.0 4 0 0 4 4 4 0 Bacterial membrane-spanning protein N-terminus VPS28 PF03997.12 KFY04948.1 - 0.11 12.1 6.7 0.16 11.6 0.1 2.8 2 0 0 2 2 2 0 VPS28 protein GP41 PF00517.17 KFY04948.1 - 0.21 11.5 0.1 0.21 11.5 0.1 3.0 2 1 1 3 3 3 0 Retroviral envelope protein HALZ PF02183.18 KFY04948.1 - 0.31 11.3 3.2 9.3 6.6 0.7 3.7 3 0 0 3 3 3 0 Homeobox associated leucine zipper TipAS PF07739.13 KFY04948.1 - 8.7 6.9 9.8 1.3 9.5 0.2 4.3 4 1 1 5 5 5 0 TipAS antibiotic-recognition domain Cauli_AT PF03233.13 KFY04948.1 - 9.1 6.2 19.5 4.3 7.2 0.1 5.3 4 2 2 6 6 6 0 Aphid transmission protein DUF5572 PF17733.1 KFY04949.1 - 5.9e-20 70.8 0.1 1e-19 70.1 0.1 1.4 1 0 0 1 1 1 1 Family of unknown function (DUF5572) LSM14 PF12701.7 KFY04950.1 - 2.7e-30 104.3 0.1 4.2e-30 103.7 0.1 1.3 1 0 0 1 1 1 1 Scd6-like Sm domain FDF PF09532.10 KFY04950.1 - 1.6e-15 57.9 6.7 8.4e-15 55.5 6.7 2.3 1 1 0 1 1 1 1 FDF domain SM-ATX PF14438.6 KFY04950.1 - 3.4e-06 27.1 0.0 5.8e-06 26.3 0.0 1.4 1 0 0 1 1 1 1 Ataxin 2 SM domain ER_lumen_recept PF00810.18 KFY04951.1 - 7.3e-54 182.6 10.8 7.3e-54 182.6 10.8 1.5 2 0 0 2 2 2 1 ER lumen protein retaining receptor DUF485 PF04341.12 KFY04951.1 - 0.0045 16.9 0.2 0.0045 16.9 0.2 3.0 2 1 1 3 3 3 1 Protein of unknown function, DUF485 PQ-loop PF04193.14 KFY04951.1 - 0.99 9.2 13.2 1.9 8.3 0.2 3.9 4 0 0 4 4 4 0 PQ loop repeat Herpes_gE PF02480.16 KFY04952.1 - 0.00033 19.5 0.0 0.0005 18.9 0.0 1.2 1 0 0 1 1 1 1 Alphaherpesvirus glycoprotein E SPX PF03105.19 KFY04952.1 - 0.43 10.4 7.5 0.58 10.0 7.5 1.2 1 0 0 1 1 1 0 SPX domain Med13_C PF06333.12 KFY04952.1 - 0.65 9.2 9.8 0.91 8.7 9.8 1.2 1 0 0 1 1 1 0 Mediator complex subunit 13 C-terminal domain ORC6 PF05460.13 KFY04952.1 - 9.1 5.4 11.8 12 5.0 11.8 1.2 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) CAP59_mtransfer PF11735.8 KFY04953.1 - 4.1e-66 223.1 0.0 5.1e-66 222.8 0.0 1.1 1 0 0 1 1 1 1 Cryptococcal mannosyltransferase 1 ATP-synt_ab PF00006.25 KFY04954.1 - 3e-61 206.8 0.0 4.6e-61 206.2 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_N PF02874.23 KFY04954.1 - 3.2e-23 82.0 0.4 9.6e-23 80.5 0.4 1.9 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain AAA PF00004.29 KFY04954.1 - 0.0084 16.5 0.1 0.5 10.8 0.0 2.7 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) RsgA_GTPase PF03193.16 KFY04954.1 - 0.014 15.3 0.8 0.028 14.3 0.1 1.8 2 0 0 2 2 2 0 RsgA GTPase NB-ARC PF00931.22 KFY04954.1 - 0.018 14.3 0.3 0.11 11.7 0.1 2.0 2 0 0 2 2 2 0 NB-ARC domain ATPase_2 PF01637.18 KFY04954.1 - 0.026 14.5 0.0 0.059 13.3 0.0 1.5 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea ATPase PF06745.13 KFY04954.1 - 0.027 13.8 0.2 0.045 13.1 0.2 1.4 1 0 0 1 1 1 0 KaiC AAA_19 PF13245.6 KFY04954.1 - 0.027 14.8 1.2 0.48 10.8 0.2 2.3 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 KFY04954.1 - 0.057 13.8 0.0 0.16 12.4 0.0 1.8 2 0 0 2 2 2 0 RNA helicase NACHT PF05729.12 KFY04954.1 - 0.057 13.3 0.2 0.14 12.1 0.0 1.7 2 0 0 2 2 2 0 NACHT domain Alpha-amylase_C PF02806.18 KFY04955.1 - 4.2e-25 88.0 0.0 9.1e-25 87.0 0.0 1.6 1 0 0 1 1 1 1 Alpha amylase, C-terminal all-beta domain CBM_48 PF02922.18 KFY04955.1 - 1.1e-19 70.5 0.1 3.1e-19 69.1 0.1 1.8 1 0 0 1 1 1 1 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) Alpha-amylase PF00128.24 KFY04955.1 - 2.6e-15 56.8 0.2 9e-12 45.2 0.1 2.4 1 1 1 2 2 2 2 Alpha amylase, catalytic domain hDGE_amylase PF14701.6 KFY04955.1 - 0.12 11.4 0.1 0.23 10.5 0.1 1.4 1 0 0 1 1 1 0 Glycogen debranching enzyme, glucanotransferase domain AAA_2 PF07724.14 KFY04956.1 - 7.2e-37 127.1 0.0 2e-36 125.7 0.0 1.7 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA PF00004.29 KFY04956.1 - 5.8e-12 46.2 0.0 9.9e-12 45.4 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.9 KFY04956.1 - 4.1e-08 33.2 0.0 1.1e-07 31.9 0.0 1.7 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA_5 PF07728.14 KFY04956.1 - 6.5e-06 26.2 0.0 1.4e-05 25.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 KFY04956.1 - 0.00044 20.5 0.3 0.0039 17.5 0.3 2.2 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 KFY04956.1 - 0.00049 20.5 0.0 0.0021 18.5 0.0 1.9 1 1 0 1 1 1 1 AAA ATPase domain MCM PF00493.23 KFY04956.1 - 0.00072 18.7 0.0 0.0015 17.7 0.0 1.4 1 0 0 1 1 1 1 MCM P-loop domain IstB_IS21 PF01695.17 KFY04956.1 - 0.0041 16.9 0.7 0.0089 15.8 0.0 1.7 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_7 PF12775.7 KFY04956.1 - 0.0073 15.8 0.0 0.016 14.8 0.0 1.5 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_24 PF13479.6 KFY04956.1 - 0.011 15.4 0.0 0.019 14.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.26 KFY04956.1 - 0.027 14.2 0.0 1.9 8.2 0.0 2.4 2 0 0 2 2 2 0 Sigma-54 interaction domain Mg_chelatase PF01078.21 KFY04956.1 - 0.049 13.0 0.1 5 6.5 0.0 3.0 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI RuvB_N PF05496.12 KFY04956.1 - 0.054 13.3 0.2 1 9.1 0.0 2.3 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain AAA_19 PF13245.6 KFY04956.1 - 0.056 13.8 0.0 0.11 12.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 KFY04956.1 - 0.057 14.0 0.1 0.15 12.7 0.0 1.8 2 0 0 2 2 1 0 AAA domain AAA_14 PF13173.6 KFY04956.1 - 0.078 13.0 0.0 0.16 12.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 KFY04956.1 - 0.088 13.0 0.4 0.23 11.6 0.0 1.9 2 0 0 2 2 1 0 AAA domain ABC_tran PF00005.27 KFY04956.1 - 0.09 13.3 0.0 0.19 12.3 0.0 1.5 1 0 0 1 1 1 0 ABC transporter AAA_21 PF13304.6 KFY04956.1 - 0.11 12.3 0.0 0.21 11.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system RNA_helicase PF00910.22 KFY04956.1 - 0.12 12.7 0.0 0.24 11.8 0.0 1.5 1 0 0 1 1 1 0 RNA helicase TsaE PF02367.17 KFY04956.1 - 0.15 12.1 0.0 0.37 10.8 0.0 1.6 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_6 PF12774.7 KFY04956.1 - 0.19 10.7 0.0 0.32 9.9 0.0 1.3 1 0 0 1 1 1 0 Hydrolytic ATP binding site of dynein motor region NACHT PF05729.12 KFY04956.1 - 0.2 11.6 0.0 0.39 10.6 0.0 1.5 1 0 0 1 1 1 0 NACHT domain COX4 PF02936.14 KFY04957.1 - 3.3e-48 163.2 0.0 4.4e-48 162.8 0.0 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase subunit IV DUF3106 PF11304.8 KFY04957.1 - 0.011 16.2 2.0 0.021 15.3 2.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3106) ArfGap PF01412.18 KFY04957.1 - 0.087 12.9 0.0 0.18 11.9 0.0 1.5 1 0 0 1 1 1 0 Putative GTPase activating protein for Arf Gp_dh_C PF02800.20 KFY04958.1 - 6e-70 233.9 0.7 1e-69 233.2 0.7 1.4 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.24 KFY04958.1 - 2.8e-37 127.1 0.0 7.8e-37 125.7 0.0 1.8 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.19 KFY04958.1 - 0.074 12.4 0.1 0.17 11.2 0.0 1.6 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Molybdopterin PF00384.22 KFY04959.1 - 4.3e-41 141.3 0.0 3.5e-39 135.0 0.0 2.1 1 1 0 1 1 1 1 Molybdopterin oxidoreductase Fer2_4 PF13510.6 KFY04959.1 - 1.4e-19 69.9 0.1 4e-19 68.4 0.1 1.9 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain NADH-G_4Fe-4S_3 PF10588.9 KFY04959.1 - 1.4e-17 62.9 0.2 1.4e-17 62.9 0.2 2.1 2 0 0 2 2 2 1 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region Fer2 PF00111.27 KFY04959.1 - 9.3e-08 31.9 0.4 9.3e-08 31.9 0.4 1.8 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain TPP_enzyme_M PF00205.22 KFY04959.1 - 0.034 13.9 0.0 0.27 11.0 0.0 2.1 2 0 0 2 2 2 0 Thiamine pyrophosphate enzyme, central domain Fer4 PF00037.27 KFY04959.1 - 0.15 12.0 1.2 6.2 6.8 0.3 2.6 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_19 PF06902.11 KFY04959.1 - 1 9.5 4.4 29 4.8 0.0 3.2 2 1 1 3 3 3 0 Divergent 4Fe-4S mono-cluster OTT_1508_deam PF14441.6 KFY04962.1 - 6.7e-19 67.7 0.3 1.4e-18 66.6 0.3 1.6 1 0 0 1 1 1 1 OTT_1508-like deaminase TraI_2 PF07514.11 KFY04962.1 - 0.05 12.6 0.3 0.092 11.7 0.3 1.4 1 0 0 1 1 1 0 Putative helicase Pox_ser-thr_kin PF05445.11 KFY04964.1 - 0.02 13.9 0.0 0.038 13.0 0.0 1.4 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase MFS_1 PF07690.16 KFY04967.1 - 5.1e-34 117.7 26.5 5.1e-34 117.7 26.5 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily OAD_gamma PF04277.13 KFY04967.1 - 0.067 13.8 0.5 23 5.7 0.0 2.8 2 0 0 2 2 2 0 Oxaloacetate decarboxylase, gamma chain PXA PF02194.15 KFY04967.1 - 0.13 12.2 0.6 0.34 10.8 0.1 1.8 2 0 0 2 2 2 0 PXA domain Glyco_hydro_88 PF07470.13 KFY04969.1 - 1.1e-92 310.7 2.5 1.3e-92 310.5 2.5 1.0 1 0 0 1 1 1 1 Glycosyl Hydrolase Family 88 Glyco_hydro_127 PF07944.12 KFY04969.1 - 0.062 11.8 0.3 0.26 9.7 0.3 1.8 1 1 0 1 1 1 0 Beta-L-arabinofuranosidase, GH127 Glyco_hydro_76 PF03663.14 KFY04969.1 - 0.13 11.7 9.2 0.18 11.3 0.9 2.9 1 1 1 3 3 3 0 Glycosyl hydrolase family 76 CBM-like PF14683.6 KFY04970.1 - 8.5e-41 139.6 0.1 1.9e-40 138.5 0.0 1.6 2 0 0 2 2 2 1 Polysaccharide lyase family 4, domain III fn3_3 PF14686.6 KFY04970.1 - 1.9e-10 40.3 0.1 6.4e-10 38.7 0.1 2.0 1 0 0 1 1 1 1 Polysaccharide lyase family 4, domain II CarboxypepD_reg PF13620.6 KFY04970.1 - 4.6e-08 33.2 0.2 2.9e-05 24.3 0.0 2.7 2 0 0 2 2 2 2 Carboxypeptidase regulatory-like domain CarbopepD_reg_2 PF13715.6 KFY04970.1 - 0.014 15.4 0.0 1.4 9.0 0.0 3.2 2 1 0 2 2 2 0 CarboxypepD_reg-like domain DUF2012 PF09430.10 KFY04970.1 - 0.091 12.9 0.0 0.39 10.8 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2012) RhgB_N PF09284.10 KFY04970.1 - 0.1 12.1 0.0 0.17 11.4 0.0 1.3 1 0 0 1 1 1 0 Rhamnogalacturonan lyase B, N-terminal Ank_2 PF12796.7 KFY04974.1 - 3.3e-58 194.2 12.5 8.1e-15 55.2 2.0 5.4 1 1 5 6 6 6 6 Ankyrin repeats (3 copies) Ank PF00023.30 KFY04974.1 - 1.1e-40 136.3 14.7 1.6e-05 25.2 0.0 9.8 9 0 0 9 9 9 8 Ankyrin repeat Ank_3 PF13606.6 KFY04974.1 - 3.3e-39 128.4 11.3 4.4e-05 23.5 0.1 9.7 9 0 0 9 9 9 7 Ankyrin repeat Ank_4 PF13637.6 KFY04974.1 - 1.8e-38 130.4 9.1 1.4e-09 38.3 0.1 7.3 2 1 4 7 7 7 6 Ankyrin repeats (many copies) Ank_5 PF13857.6 KFY04974.1 - 1.5e-28 98.5 11.4 3.7e-05 23.9 0.1 7.1 3 2 5 8 8 8 7 Ankyrin repeats (many copies) NACHT PF05729.12 KFY04974.1 - 1.5e-08 34.7 0.0 3.6e-08 33.5 0.0 1.6 1 0 0 1 1 1 1 NACHT domain Helo_like_N PF17111.5 KFY04974.1 - 0.0021 17.4 0.1 0.0067 15.8 0.0 1.9 2 0 0 2 2 2 1 Fungal N-terminal domain of STAND proteins AAA_22 PF13401.6 KFY04974.1 - 0.005 17.1 0.0 0.031 14.6 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 KFY04974.1 - 0.0062 16.9 0.0 0.022 15.2 0.0 1.9 1 0 0 1 1 1 1 AAA ATPase domain Ribosomal_S6 PF01250.17 KFY04974.1 - 0.079 13.2 0.0 6.6 7.1 0.0 3.4 3 0 0 3 3 3 0 Ribosomal protein S6 UCH_1 PF13423.6 KFY04975.1 - 4e-100 335.5 0.0 7e-100 334.7 0.0 1.4 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase RNase_T PF00929.24 KFY04975.1 - 6.8e-17 62.5 0.0 1.2e-16 61.7 0.0 1.5 1 0 0 1 1 1 1 Exonuclease GTP_EFTU PF00009.27 KFY04976.1 - 2e-41 141.7 0.0 3.8e-41 140.8 0.0 1.5 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 KFY04976.1 - 1.5e-28 99.3 0.0 5.7e-28 97.5 0.0 2.0 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 KFY04976.1 - 2.8e-06 27.6 0.4 6.4e-06 26.5 0.4 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 KFY04976.1 - 0.00056 20.0 0.1 0.0032 17.5 0.1 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase Mitofilin PF09731.9 KFY04976.1 - 4.2 6.1 11.1 6.8 5.4 11.1 1.2 1 0 0 1 1 1 0 Mitochondrial inner membrane protein Ran-binding PF05508.11 KFY04977.1 - 5.2e-114 380.4 0.0 6.8e-114 380.0 0.0 1.1 1 0 0 1 1 1 1 RanGTP-binding protein TRAUB PF08164.12 KFY04978.1 - 1.6e-28 99.0 0.0 1.6e-28 99.0 0.0 3.1 3 0 0 3 3 3 1 Apoptosis-antagonizing transcription factor, C-terminal AATF-Che1 PF13339.6 KFY04978.1 - 7.4e-27 94.7 7.1 7.4e-27 94.7 7.1 2.8 2 1 0 2 2 2 1 Apoptosis antagonizing transcription factor DUF5051 PF16473.5 KFY04978.1 - 0.059 13.4 2.3 0.05 13.6 0.8 1.7 2 0 0 2 2 2 0 3' exoribonuclease, RNase T-like ParA PF10609.9 KFY04979.1 - 7.4e-94 313.8 0.0 8.7e-94 313.6 0.0 1.0 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase CbiA PF01656.23 KFY04979.1 - 1.5e-12 47.7 0.0 6.4e-10 39.2 0.0 2.8 3 1 0 3 3 3 2 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.6 KFY04979.1 - 4.2e-09 36.6 0.2 2.2e-07 31.0 0.1 2.1 2 0 0 2 2 2 1 AAA domain MipZ PF09140.11 KFY04979.1 - 1.3e-05 24.7 0.0 1.8e-05 24.2 0.0 1.3 1 1 0 1 1 1 1 ATPase MipZ ArsA_ATPase PF02374.15 KFY04979.1 - 0.0005 19.3 0.9 0.016 14.4 0.5 2.1 2 0 0 2 2 2 1 Anion-transporting ATPase AAA_25 PF13481.6 KFY04979.1 - 0.001 18.7 0.2 0.0028 17.3 0.0 1.8 3 0 0 3 3 3 1 AAA domain Fer4_NifH PF00142.18 KFY04979.1 - 0.024 14.1 0.0 1.1 8.6 0.0 2.2 2 0 0 2 2 2 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family AAA_26 PF13500.6 KFY04979.1 - 0.034 13.9 0.2 1.1 9.0 0.0 2.2 2 0 0 2 2 2 0 AAA domain CBP_BcsQ PF06564.12 KFY04979.1 - 0.2 11.1 0.2 1.1 8.6 0.1 1.9 2 0 0 2 2 2 0 Cellulose biosynthesis protein BcsQ 3HCDH_N PF02737.18 KFY04982.1 - 6.3e-31 107.6 0.0 7.6e-31 107.4 0.0 1.1 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.22 KFY04982.1 - 2e-08 34.8 0.0 3.8e-08 33.8 0.0 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain AlaDh_PNT_C PF01262.21 KFY04982.1 - 0.11 11.7 0.0 0.16 11.3 0.0 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_2 PF03446.15 KFY04982.1 - 0.23 11.6 0.0 0.35 11.0 0.0 1.4 1 1 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Zn_clus PF00172.18 KFY04983.1 - 0.0018 18.3 11.8 0.0034 17.5 11.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KFY04983.1 - 0.0075 15.3 1.9 0.014 14.4 0.7 2.0 2 1 0 2 2 2 1 Fungal specific transcription factor domain Histidinol_dh PF00815.20 KFY04984.1 - 1.1e-135 452.8 0.0 1.4e-135 452.5 0.0 1.0 1 0 0 1 1 1 1 Histidinol dehydrogenase Mito_carr PF00153.27 KFY04985.1 - 5.4e-52 173.7 2.3 6e-17 61.3 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Tim17 PF02466.19 KFY04985.1 - 0.9 9.9 4.2 18 5.8 4.2 2.5 1 1 0 1 1 1 0 Tim17/Tim22/Tim23/Pmp24 family MFS_1 PF07690.16 KFY04986.1 - 3.4e-36 124.9 30.7 4.7e-36 124.4 30.7 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF4231 PF14015.6 KFY04986.1 - 1.8 9.0 8.8 20 5.7 0.1 3.5 2 1 1 3 3 3 0 Protein of unknown function (DUF4231) MASE2 PF05230.11 KFY04986.1 - 7.3 6.7 11.6 0.23 11.5 2.0 3.0 2 1 0 3 3 3 0 MASE2 domain DUF1772 PF08592.11 KFY04986.1 - 7.4 6.9 15.3 0.032 14.5 1.2 3.3 1 1 2 3 3 3 0 Domain of unknown function (DUF1772) OrsD PF12013.8 KFY04987.1 - 8.5e-19 68.1 0.4 1.2e-18 67.6 0.4 1.2 1 0 0 1 1 1 1 Orsellinic acid/F9775 biosynthesis cluster protein D zf-C2H2_12 PF18658.1 KFY04987.1 - 0.12 12.0 1.3 0.97 9.1 0.1 2.3 2 1 0 2 2 2 0 Zinc-finger C2H2-type DNA_pol_A_exo1 PF01612.20 KFY04991.1 - 6.5e-39 133.4 0.1 9.3e-39 132.9 0.1 1.2 1 0 0 1 1 1 1 3'-5' exonuclease PMC2NT PF08066.12 KFY04991.1 - 2e-28 98.9 0.1 5.7e-28 97.5 0.1 1.8 1 0 0 1 1 1 1 PMC2NT (NUC016) domain HRDC PF00570.23 KFY04991.1 - 7.7e-14 51.4 0.0 3.2e-13 49.4 0.0 2.2 1 0 0 1 1 1 1 HRDC domain DUF2833 PF11090.8 KFY04991.1 - 0.16 12.3 0.0 0.32 11.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2833) UPF0203 PF05254.12 KFY04992.1 - 5.6e-27 93.8 0.6 6.4e-27 93.6 0.6 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0203) COX17 PF05051.13 KFY04992.1 - 8.6e-05 22.8 0.1 0.00018 21.8 0.1 1.5 1 1 0 1 1 1 1 Cytochrome C oxidase copper chaperone (COX17) Cmc1 PF08583.10 KFY04992.1 - 0.00095 19.1 1.9 0.041 13.9 0.2 2.3 1 1 1 2 2 2 2 Cytochrome c oxidase biogenesis protein Cmc1 like NDUF_B7 PF05676.13 KFY04992.1 - 0.035 13.8 0.9 3.9 7.3 0.0 2.2 2 0 0 2 2 2 0 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) UCR_hinge PF02320.16 KFY04992.1 - 0.1 12.8 2.4 0.84 9.9 2.4 2.0 1 1 0 1 1 1 0 Ubiquinol-cytochrome C reductase hinge protein DUF3128 PF11326.8 KFY04992.1 - 0.12 12.7 1.4 0.56 10.6 1.4 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF3128) Gpi1 PF05024.15 KFY04993.1 - 8.5e-77 257.5 9.0 8.5e-77 257.5 9.0 1.6 2 0 0 2 2 2 1 N-acetylglucosaminyl transferase component (Gpi1) 7tm_1 PF00001.21 KFY04993.1 - 0.051 12.9 0.6 0.11 11.8 0.6 1.5 1 0 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) IDO PF01231.18 KFY04998.1 - 2.9e-76 257.0 0.0 3.2e-76 256.8 0.0 1.0 1 0 0 1 1 1 1 Indoleamine 2,3-dioxygenase Tom6 PF17112.5 KFY04999.1 - 0.083 12.4 0.1 0.11 12.0 0.1 1.2 1 0 0 1 1 1 0 Mitochondrial import receptor subunit Tom6, fungal Cgr1 PF03879.14 KFY05004.1 - 2.4e-29 101.9 28.8 2.7e-29 101.7 28.8 1.0 1 0 0 1 1 1 1 Cgr1 family Ndufs5 PF10200.9 KFY05004.1 - 0.5 10.7 10.6 1.1 9.6 9.6 1.8 1 1 1 2 2 2 0 NADH:ubiquinone oxidoreductase, NDUFS5-15kDa Silic_transp PF03842.13 KFY05004.1 - 2.3 6.4 4.8 2.6 6.3 4.8 1.0 1 0 0 1 1 1 0 Silicon transporter ST7 PF04184.12 KFY05004.1 - 9.3 4.6 9.7 11 4.3 9.7 1.0 1 0 0 1 1 1 0 ST7 protein Mito_carr PF00153.27 KFY05005.1 - 6.6e-63 208.7 0.3 5.1e-21 74.4 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein TspO_MBR PF03073.15 KFY05006.1 - 1.2e-43 148.4 1.6 1.6e-43 148.0 1.6 1.1 1 0 0 1 1 1 1 TspO/MBR family Cwf_Cwc_15 PF04889.12 KFY05010.1 - 0.26 11.0 13.7 0.23 11.2 7.6 2.5 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein CAF1A PF12253.8 KFY05010.1 - 1.6 8.9 13.6 2.2 8.5 0.2 2.9 2 0 0 2 2 2 0 Chromatin assembly factor 1 subunit A PTPRCAP PF15713.5 KFY05010.1 - 3.2 8.0 12.4 1.5 9.1 6.5 2.4 2 0 0 2 2 2 0 Protein tyrosine phosphatase receptor type C-associated Rad4 PF03835.15 KFY05011.1 - 1.7e-31 108.9 0.2 5e-31 107.4 0.2 1.8 1 0 0 1 1 1 1 Rad4 transglutaminase-like domain BHD_3 PF10405.9 KFY05011.1 - 2.3e-27 95.2 0.0 4.4e-27 94.3 0.0 1.5 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 3 BHD_2 PF10404.9 KFY05011.1 - 1.1e-16 61.5 1.8 1.3e-15 58.0 0.1 3.3 2 0 0 2 2 2 1 Rad4 beta-hairpin domain 2 BHD_1 PF10403.9 KFY05011.1 - 1.5e-16 60.0 0.0 3.5e-16 58.8 0.0 1.7 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 1 Transglut_core PF01841.19 KFY05011.1 - 0.04 14.4 0.0 0.24 11.9 0.0 2.3 1 1 0 1 1 1 0 Transglutaminase-like superfamily p450 PF00067.22 KFY05012.1 - 2.7e-53 181.4 0.0 3.5e-53 181.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 CesT PF05932.13 KFY05014.1 - 0.087 13.0 0.0 0.17 12.0 0.0 1.4 1 0 0 1 1 1 0 Tir chaperone protein (CesT) family Dyp_perox PF04261.12 KFY05014.1 - 0.11 11.4 0.0 0.16 11.0 0.0 1.1 1 0 0 1 1 1 0 Dyp-type peroxidase family PEX11 PF05648.14 KFY05015.1 - 4.2e-70 235.7 0.0 4.7e-70 235.5 0.0 1.0 1 0 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) DUF2805 PF10985.8 KFY05015.1 - 0.086 13.2 0.0 0.2 12.1 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2805) TPT PF03151.16 KFY05016.1 - 2.3e-30 106.0 19.3 2.7e-30 105.7 19.3 1.0 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 KFY05016.1 - 0.056 13.6 34.5 0.16 12.2 12.4 3.1 3 0 0 3 3 3 0 EamA-like transporter family UAA PF08449.11 KFY05016.1 - 0.092 11.9 22.3 0.21 10.7 22.3 1.6 1 1 0 1 1 1 0 UAA transporter family MFS_1 PF07690.16 KFY05017.1 - 3.9e-41 141.2 48.6 3.9e-41 141.2 48.6 2.4 1 1 1 2 2 2 1 Major Facilitator Superfamily DUF4131 PF13567.6 KFY05017.1 - 3.3 7.3 7.9 5.1 6.7 2.4 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4131) Aldo_ket_red PF00248.21 KFY05018.1 - 3e-48 164.5 0.0 3.7e-48 164.2 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Glyco_hydro_108 PF05838.12 KFY05018.1 - 0.034 14.6 0.1 14 6.3 0.0 2.7 2 0 0 2 2 2 0 Glycosyl hydrolase 108 DUF4336 PF14234.6 KFY05019.1 - 7.1e-14 51.7 0.0 2.5e-08 33.5 0.0 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF4336) DUF4566 PF15130.6 KFY05019.1 - 0.2 11.0 0.0 0.31 10.4 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4566) Fungal_trans_2 PF11951.8 KFY05020.1 - 1.1e-09 37.6 1.0 2e-09 36.7 1.0 1.4 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KFY05020.1 - 0.00014 21.9 8.6 0.00032 20.8 8.6 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Glyco_transf_17 PF04724.13 KFY05021.1 - 2e-48 165.3 3.4 2.9e-48 164.7 3.4 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 17 DUF3530 PF12048.8 KFY05021.1 - 0.064 12.7 0.2 0.11 11.8 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3530) SKG6 PF08693.10 KFY05024.1 - 0.00093 18.6 5.0 0.00093 18.6 5.0 2.1 2 0 0 2 2 2 1 Transmembrane alpha-helix domain CYYR1 PF10873.8 KFY05024.1 - 0.019 15.4 0.7 0.041 14.3 0.7 1.7 1 0 0 1 1 1 0 Cysteine and tyrosine-rich protein 1 Shisa PF13908.6 KFY05024.1 - 0.034 14.4 0.0 0.052 13.8 0.0 1.3 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator VSP PF03302.13 KFY05024.1 - 0.17 10.7 0.3 0.24 10.2 0.3 1.1 1 0 0 1 1 1 0 Giardia variant-specific surface protein RIFIN PF02009.16 KFY05024.1 - 0.25 11.2 0.0 0.34 10.8 0.0 1.2 1 0 0 1 1 1 0 Rifin PGG PF13962.6 KFY05025.1 - 0.01 15.6 0.1 0.012 15.5 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function LRR19-TM PF15176.6 KFY05025.1 - 0.085 12.9 0.1 0.11 12.5 0.1 1.2 1 0 0 1 1 1 0 Leucine-rich repeat family 19 TM domain DUF4711 PF15829.5 KFY05025.1 - 0.18 11.8 0.0 0.18 11.8 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4711) Lactamase_B_2 PF12706.7 KFY05026.1 - 2.6e-10 40.2 0.0 4e-10 39.5 0.0 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain bZIP_1 PF00170.21 KFY05027.1 - 0.0003 20.8 8.9 0.00053 20.0 8.9 1.4 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 KFY05027.1 - 0.0012 18.9 5.4 0.0019 18.2 5.4 1.3 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.17 KFY05027.1 - 2.3 8.8 9.4 0.47 11.0 5.7 1.8 2 0 0 2 2 2 0 bZIP Maf transcription factor CHDCT2 PF08074.11 KFY05028.1 - 0.097 12.8 2.2 0.15 12.2 2.2 1.3 1 1 0 1 1 1 0 CHDCT2 (NUC038) domain DUF4600 PF15372.6 KFY05029.1 - 0.001 19.5 0.2 0.0012 19.3 0.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4600) DUF4763 PF15960.5 KFY05029.1 - 0.0011 18.3 2.8 0.0014 18.0 2.8 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4763) bZIP_2 PF07716.15 KFY05029.1 - 0.0029 17.7 4.7 0.0048 16.9 4.7 1.4 1 0 0 1 1 1 1 Basic region leucine zipper HALZ PF02183.18 KFY05029.1 - 0.0033 17.6 2.0 0.0044 17.2 2.0 1.2 1 0 0 1 1 1 1 Homeobox associated leucine zipper DUF4515 PF14988.6 KFY05029.1 - 0.0047 16.8 1.6 0.0059 16.5 1.6 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4515) Cnn_1N PF07989.11 KFY05029.1 - 0.0079 16.3 1.6 0.0099 16.0 1.6 1.2 1 0 0 1 1 1 1 Centrosomin N-terminal motif 1 HMMR_C PF15908.5 KFY05029.1 - 0.01 16.1 1.2 0.013 15.8 1.2 1.1 1 0 0 1 1 1 0 Hyaluronan mediated motility receptor C-terminal APC_N_CC PF16689.5 KFY05029.1 - 0.01 15.9 2.0 0.017 15.2 2.0 1.3 1 0 0 1 1 1 0 Coiled-coil N-terminus of APC, dimerisation domain bZIP_1 PF00170.21 KFY05029.1 - 0.061 13.4 3.3 0.086 12.9 3.3 1.2 1 0 0 1 1 1 0 bZIP transcription factor Pilin PF00114.19 KFY05029.1 - 0.071 14.0 0.2 0.085 13.8 0.2 1.2 1 0 0 1 1 1 0 Pilin (bacterial filament) YabA PF06156.13 KFY05029.1 - 0.11 13.1 0.6 0.15 12.7 0.6 1.2 1 0 0 1 1 1 0 Initiation control protein YabA Zn_clus PF00172.18 KFY05031.1 - 0.00089 19.3 12.6 0.002 18.2 12.6 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HET PF06985.11 KFY05034.1 - 3.5e-10 40.4 0.0 6.8e-10 39.5 0.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) E1-N PF14463.6 KFY05034.1 - 0.018 14.9 0.5 0.031 14.1 0.5 1.3 1 0 0 1 1 1 0 E1 N-terminal domain Glutaredoxin PF00462.24 KFY05034.1 - 0.046 14.0 0.0 0.091 13.0 0.0 1.5 1 0 0 1 1 1 0 Glutaredoxin DIOX_N PF14226.6 KFY05035.1 - 8e-25 87.9 0.0 1.2e-24 87.3 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 KFY05035.1 - 6e-19 68.4 0.0 1.1e-18 67.5 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily MFS_1 PF07690.16 KFY05036.1 - 2.7e-16 59.5 23.6 3.8e-16 59.0 23.6 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily OATP PF03137.20 KFY05036.1 - 0.0023 16.3 2.3 0.0062 14.9 2.2 2.0 1 1 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family DIE2_ALG10 PF04922.12 KFY05036.1 - 0.26 10.5 2.9 0.37 10.0 0.2 2.0 2 0 0 2 2 2 0 DIE2/ALG10 family DUF2617 PF10936.8 KFY05037.1 - 0.031 14.3 0.0 0.58 10.2 0.0 2.0 1 1 1 2 2 2 0 Protein of unknown function DUF2617 DUF4663 PF15668.5 KFY05041.1 - 0.022 13.8 2.9 0.026 13.6 2.9 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4663) Trypan_PARP PF05887.11 KFY05041.1 - 0.44 10.5 6.3 2.2 8.3 6.3 1.8 1 1 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) LSM PF01423.22 KFY05042.1 - 2.2e-21 75.3 0.6 2.5e-21 75.1 0.6 1.0 1 0 0 1 1 1 1 LSM domain Thiolase_N PF00108.23 KFY05043.1 - 1.1e-95 320.0 1.8 1.1e-95 320.0 1.8 1.8 2 0 0 2 2 2 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 KFY05043.1 - 1.4e-46 157.2 1.5 1.4e-46 157.2 1.5 1.9 2 0 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 KFY05043.1 - 9.3e-06 25.4 0.5 2.3e-05 24.1 0.3 1.8 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.10 KFY05043.1 - 0.15 11.9 2.0 1.1 9.2 0.1 2.6 3 0 0 3 3 3 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III GTP_EFTU PF00009.27 KFY05044.1 - 4.7e-47 160.0 0.0 7.3e-47 159.4 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFTUD2 PF16004.5 KFY05044.1 - 3.9e-37 127.6 9.7 7.3e-37 126.7 9.7 1.5 1 0 0 1 1 1 1 116 kDa U5 small nuclear ribonucleoprotein component N-terminus EFG_IV PF03764.18 KFY05044.1 - 2.5e-21 75.7 0.0 6e-21 74.4 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_C PF00679.24 KFY05044.1 - 7.8e-18 64.3 0.0 2.4e-17 62.7 0.0 1.9 2 0 0 2 2 2 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 KFY05044.1 - 2.9e-10 40.4 0.0 6.4e-10 39.3 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_II PF14492.6 KFY05044.1 - 1e-06 28.7 0.0 2.2e-06 27.6 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II MMR_HSR1 PF01926.23 KFY05044.1 - 4.3e-06 26.8 0.1 8.4e-06 25.9 0.1 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 KFY05044.1 - 0.062 12.7 0.1 0.2 11.1 0.1 1.8 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit ADH_N PF08240.12 KFY05045.1 - 4.6e-27 94.1 2.4 5.7e-27 93.8 1.2 1.9 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_N_assoc PF13823.6 KFY05045.1 - 1.5e-07 31.2 1.0 3.7e-07 29.9 1.0 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-associated ADH_zinc_N PF00107.26 KFY05045.1 - 1.2e-06 28.5 0.0 0.00096 19.1 0.0 2.4 2 0 0 2 2 2 2 Zinc-binding dehydrogenase Thioredoxin_4 PF13462.6 KFY05046.1 - 1e-06 29.0 0.0 3e-06 27.5 0.0 1.9 1 1 0 1 1 1 1 Thioredoxin DUF3844 PF12955.7 KFY05047.1 - 6e-33 113.1 2.8 6e-33 113.1 2.8 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF3844) GNAT_acetyltr_2 PF13718.6 KFY05048.1 - 1.2e-95 319.3 0.0 2.3e-95 318.3 0.0 1.5 1 0 0 1 1 1 1 GNAT acetyltransferase 2 tRNA_bind_2 PF13725.6 KFY05048.1 - 3.5e-90 301.8 0.0 6.1e-90 301.0 0.0 1.4 1 0 0 1 1 1 1 Possible tRNA binding domain Helicase_RecD PF05127.14 KFY05048.1 - 1.2e-64 217.4 0.0 4e-64 215.7 0.0 1.9 2 0 0 2 2 2 1 Helicase DUF1726 PF08351.11 KFY05048.1 - 1.9e-34 117.5 0.0 4.7e-34 116.2 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1726) AAA_30 PF13604.6 KFY05048.1 - 0.00028 20.7 0.1 0.027 14.2 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 KFY05048.1 - 0.0009 19.5 0.0 0.042 14.1 0.0 2.8 2 0 0 2 2 2 1 AAA domain GHMP_kinases_N PF00288.26 KFY05048.1 - 0.11 12.8 0.1 0.31 11.3 0.1 1.7 1 0 0 1 1 1 0 GHMP kinases N terminal domain Glyco_transf_90 PF05686.12 KFY05049.1 - 0.061 12.2 0.2 11 4.8 0.0 2.7 3 0 0 3 3 3 0 Glycosyl transferase family 90 Tmpp129 PF10272.9 KFY05049.1 - 0.21 10.9 1.4 0.25 10.6 0.2 1.6 2 0 0 2 2 2 0 Putative transmembrane protein precursor Lipase_3 PF01764.25 KFY05050.1 - 2.1e-31 108.7 0.0 3e-31 108.2 0.0 1.2 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.7 KFY05050.1 - 0.013 16.1 0.1 0.016 15.8 0.1 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 KFY05050.1 - 0.043 13.1 0.1 0.067 12.4 0.1 1.2 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Thioesterase PF00975.20 KFY05050.1 - 0.084 13.0 0.8 0.14 12.3 0.8 1.3 1 0 0 1 1 1 0 Thioesterase domain Cellulase PF00150.18 KFY05051.1 - 1.8e-48 165.4 0.0 2.8e-48 164.8 0.0 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) NmrA PF05368.13 KFY05051.1 - 2.9e-09 36.9 0.0 0.0023 17.5 0.0 2.3 2 0 0 2 2 2 2 NmrA-like family NAD_binding_10 PF13460.6 KFY05051.1 - 0.0027 17.6 0.0 0.013 15.4 0.0 2.1 3 0 0 3 3 3 1 NAD(P)H-binding XLF PF09302.11 KFY05052.1 - 3.1e-47 161.1 0.1 3.1e-47 161.1 0.1 2.4 3 0 0 3 3 3 1 XLF-Cernunnos, XRcc4-like factor, NHEJ component DUF3807 PF12720.7 KFY05053.1 - 1.4e-47 162.3 4.7 1.6e-47 162.1 4.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3807) Forkhead PF00250.18 KFY05055.1 - 1e-17 64.1 0.0 2e-17 63.2 0.0 1.5 1 0 0 1 1 1 1 Forkhead domain Cactin_mid PF10312.9 KFY05056.1 - 2.1e-66 223.4 8.9 3.6e-66 222.7 8.9 1.3 1 0 0 1 1 1 1 Conserved mid region of cactin CactinC_cactus PF09732.9 KFY05056.1 - 5.5e-58 194.3 6.1 9.2e-58 193.6 6.1 1.4 1 0 0 1 1 1 1 Cactus-binding C-terminus of cactin protein SF3A2 PF16835.5 KFY05056.1 - 0.017 15.5 0.0 0.068 13.5 0.0 2.0 1 0 0 1 1 1 0 Pre-mRNA-splicing factor SF3a complex subunit 2 (Prp11) TPR_20 PF14561.6 KFY05056.1 - 0.024 15.0 0.1 0.062 13.6 0.1 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat YolD PF08863.10 KFY05056.1 - 0.069 13.2 1.2 0.55 10.3 0.1 2.5 2 0 0 2 2 2 0 YolD-like protein DUF1087 PF06465.13 KFY05056.1 - 0.2 11.7 2.6 0.47 10.5 0.5 2.6 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1087) Mucin-like PF16058.5 KFY05056.1 - 2.5 8.2 6.0 0.86 9.7 1.3 2.1 2 0 0 2 2 2 0 Mucin-like Atg14 PF10186.9 KFY05057.1 - 1.9e-12 46.9 14.3 6.5e-11 41.9 9.4 2.9 2 1 0 2 2 2 1 Vacuolar sorting 38 and autophagy-related subunit 14 VPS38 PF17649.1 KFY05057.1 - 2.5e-09 36.5 1.3 0.0039 16.1 0.2 3.7 3 1 0 3 3 3 3 Vacuolar protein sorting 38 APG6 PF04111.12 KFY05057.1 - 0.00025 21.0 0.0 0.00071 19.6 0.0 1.7 2 0 0 2 2 2 1 Apg6 BARA domain DUF3347 PF11827.8 KFY05057.1 - 1.5 9.0 4.7 2.4 8.3 4.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3347) SRF-TF PF00319.18 KFY05058.1 - 2.6e-25 87.7 0.2 3.3e-25 87.3 0.2 1.2 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) Dimer_Tnp_hAT PF05699.14 KFY05060.1 - 1.1e-15 57.2 0.0 1.9e-15 56.4 0.0 1.4 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region ATG11 PF10377.9 KFY05062.1 - 2.1e-43 147.4 1.0 2e-42 144.3 0.0 3.2 2 1 0 2 2 2 1 Autophagy-related protein 11 APG17 PF04108.12 KFY05062.1 - 1.4e-06 27.7 1.5 0.00032 19.9 0.6 5.1 3 2 2 5 5 5 2 Autophagy protein Apg17 Tropomyosin PF00261.20 KFY05062.1 - 0.00066 19.1 17.1 0.00066 19.1 17.1 5.7 4 1 1 5 5 5 1 Tropomyosin Cleaved_Adhesin PF07675.11 KFY05062.1 - 0.0011 18.9 0.0 0.0023 17.9 0.0 1.4 1 0 0 1 1 1 1 Cleaved Adhesin Domain Flagellin_C PF00700.21 KFY05062.1 - 0.19 12.1 3.5 0.23 11.8 0.4 2.9 2 0 0 2 2 2 0 Bacterial flagellin C-terminal helical region T2SSF PF00482.23 KFY05062.1 - 0.23 11.4 1.5 1.2 9.1 1.5 2.2 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein F HAP1_N PF04849.13 KFY05062.1 - 0.7 9.0 50.5 0.046 12.9 29.8 3.8 2 1 1 3 3 3 0 HAP1 N-terminal conserved region RasGAP_C PF03836.15 KFY05062.1 - 1 9.5 17.9 0.083 13.0 6.3 3.5 1 1 2 3 3 3 0 RasGAP C-terminus RBD-FIP PF09457.10 KFY05062.1 - 3.6 7.6 5.9 33 4.5 1.0 3.0 2 0 0 2 2 2 0 FIP domain Spc7 PF08317.11 KFY05062.1 - 6.7 5.5 56.5 0.027 13.4 13.5 5.2 3 1 3 6 6 6 0 Spc7 kinetochore protein CENP-H PF05837.12 KFY05063.1 - 1.7e-35 121.8 8.7 9.5e-34 116.2 3.5 2.0 2 0 0 2 2 2 2 Centromere protein H (CENP-H) DUF4482 PF14818.6 KFY05063.1 - 0.011 16.6 1.0 4.2 8.2 0.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4482) TMCO5 PF14992.6 KFY05063.1 - 0.011 15.3 0.8 0.011 15.3 0.8 1.9 1 1 0 2 2 2 0 TMCO5 family Nop52 PF05997.12 KFY05064.1 - 6.4e-63 212.4 0.0 7.3e-63 212.2 0.0 1.0 1 0 0 1 1 1 1 Nucleolar protein,Nop52 MMU163 PF17119.5 KFY05064.1 - 0.07 12.3 0.0 0.1 11.8 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial protein up-regulated during meiosis DAGK_cat PF00781.24 KFY05065.1 - 2.4e-21 75.7 0.0 3.5e-21 75.1 0.0 1.3 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain Adaptin_N PF01602.20 KFY05066.1 - 1.3e-96 324.3 11.2 2.2e-96 323.5 11.2 1.3 1 0 0 1 1 1 1 Adaptin N terminal region Coatamer_beta_C PF07718.12 KFY05066.1 - 2.4e-60 202.5 1.2 5.4e-60 201.3 1.2 1.6 1 0 0 1 1 1 1 Coatomer beta C-terminal region Coatomer_b_Cpla PF14806.6 KFY05066.1 - 9.9e-57 190.4 0.0 2.9e-56 188.9 0.0 1.8 1 0 0 1 1 1 1 Coatomer beta subunit appendage platform Cnd1 PF12717.7 KFY05066.1 - 1.2e-11 44.9 8.6 9.8e-10 38.7 0.1 3.3 1 1 0 2 2 2 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 KFY05066.1 - 3.1e-06 27.5 0.6 0.003 17.9 0.1 5.3 3 1 3 6 6 5 3 HEAT repeats Coatomer_g_Cpla PF16381.5 KFY05066.1 - 0.00021 21.4 0.0 0.00078 19.6 0.0 2.1 1 0 0 1 1 1 1 Coatomer subunit gamma-1 C-terminal appendage platform HEAT PF02985.22 KFY05066.1 - 0.0092 16.2 3.3 3.3 8.2 0.0 4.4 4 0 0 4 4 3 1 HEAT repeat DUF5578 PF17741.1 KFY05066.1 - 0.018 14.5 4.3 1.8 7.9 0.2 2.7 2 0 0 2 2 2 0 Family of unknown function (DUF5578) AP4E_app_platf PF14807.6 KFY05066.1 - 0.046 14.1 0.4 0.16 12.3 0.4 2.0 1 0 0 1 1 1 0 Adaptin AP4 complex epsilon appendage platform Phage_TAC_4 PF08748.11 KFY05066.1 - 2.1 8.7 5.8 1.5 9.1 0.1 2.6 2 0 0 2 2 2 0 Phage tail assembly chaperone HEAT_EZ PF13513.6 KFY05066.1 - 2.4 8.8 3.8 16 6.1 0.0 4.1 5 1 1 6 6 5 0 HEAT-like repeat Vac_ImportDeg PF09783.9 KFY05067.1 - 1.5e-69 232.9 0.6 2.1e-69 232.5 0.6 1.2 1 0 0 1 1 1 1 Vacuolar import and degradation protein Mago_nashi PF02792.14 KFY05067.1 - 1e-57 194.2 0.3 2.7e-57 192.9 0.2 1.7 2 0 0 2 2 2 1 Mago nashi protein Alk_phosphatase PF00245.20 KFY05070.1 - 5.2e-70 236.5 0.6 2.5e-64 217.8 0.4 2.0 2 0 0 2 2 2 2 Alkaline phosphatase Sulfatase PF00884.23 KFY05070.1 - 4.1e-06 26.4 0.1 7.7e-06 25.5 0.1 1.5 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.22 KFY05070.1 - 4.6e-06 26.5 0.1 6.9e-06 25.9 0.1 1.4 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase DUF229 PF02995.17 KFY05070.1 - 0.0014 17.3 1.1 0.0016 17.1 0.2 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF229) Metalloenzyme PF01676.18 KFY05070.1 - 0.031 13.7 0.8 3.2 7.0 0.1 2.5 3 0 0 3 3 3 0 Metalloenzyme superfamily DUF1501 PF07394.12 KFY05070.1 - 0.086 11.9 0.1 0.15 11.1 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1501) Cellulase PF00150.18 KFY05071.1 - 4.5e-14 52.6 0.4 7.6e-14 51.8 0.4 1.3 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) FAD_binding_4 PF01565.23 KFY05073.1 - 7.4e-23 80.8 0.1 1.6e-22 79.8 0.1 1.6 1 0 0 1 1 1 1 FAD binding domain Na_Ca_ex PF01699.24 KFY05074.1 - 0.0025 17.8 3.3 0.0032 17.5 1.8 1.9 1 1 1 2 2 2 1 Sodium/calcium exchanger protein DUF4396 PF14342.6 KFY05074.1 - 0.12 12.8 5.7 1.6 9.1 4.9 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4396) Asp PF00026.23 KFY05075.1 - 5e-60 203.6 1.2 8.2e-60 202.9 1.2 1.3 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 KFY05075.1 - 7.4e-13 49.1 0.2 1.4e-11 45.0 0.2 2.3 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal TAXi_C PF14541.6 KFY05075.1 - 0.0013 18.5 0.0 0.0045 16.8 0.0 1.9 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal Asp_protease_2 PF13650.6 KFY05075.1 - 0.055 14.1 0.4 6.6 7.4 0.0 2.7 2 0 0 2 2 2 0 Aspartyl protease gag-asp_proteas PF13975.6 KFY05075.1 - 0.11 13.0 0.1 1.9 9.1 0.0 2.5 2 0 0 2 2 2 0 gag-polyprotein putative aspartyl protease SCO1-SenC PF02630.14 KFY05076.1 - 3.9e-48 162.8 0.0 6.7e-48 162.0 0.0 1.4 1 0 0 1 1 1 1 SCO1/SenC AhpC-TSA PF00578.21 KFY05076.1 - 0.00017 21.5 0.0 0.00068 19.5 0.0 1.9 2 0 0 2 2 2 1 AhpC/TSA family HemY_N PF07219.13 KFY05076.1 - 0.051 13.8 10.4 1.6 9.0 1.9 3.2 2 0 0 2 2 2 0 HemY protein N-terminus Glyco_hydro_3_C PF01915.22 KFY05077.1 - 6.1e-54 183.1 0.0 1.2e-53 182.1 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 KFY05077.1 - 5.8e-40 137.6 0.0 8.8e-40 137.0 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_88 PF07470.13 KFY05077.1 - 6e-28 97.9 0.0 1.6e-27 96.5 0.0 1.5 1 1 0 1 1 1 1 Glycosyl Hydrolase Family 88 Fn3-like PF14310.6 KFY05077.1 - 9.5e-28 96.1 0.1 1.8e-27 95.2 0.1 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain DUF3372 PF11852.8 KFY05077.1 - 0.053 13.0 0.2 0.11 12.0 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3372) Stb3 PF10330.9 KFY05077.1 - 0.17 11.9 0.1 5.6 7.1 0.0 2.4 2 0 0 2 2 2 0 Putative Sin3 binding protein Toxin_8 PF07365.12 KFY05077.1 - 2.3 8.5 6.9 2.2 8.6 1.5 2.7 2 0 0 2 2 2 0 Alpha conotoxin precursor F-box-like PF12937.7 KFY05081.1 - 4e-10 39.4 0.4 1e-09 38.1 0.4 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 KFY05081.1 - 0.00026 20.8 0.5 0.00081 19.2 0.1 2.0 2 0 0 2 2 2 1 F-box domain LRR_4 PF12799.7 KFY05081.1 - 0.021 15.2 2.8 18 5.9 0.0 4.0 4 2 1 5 5 5 0 Leucine Rich repeats (2 copies) Hydrolase_6 PF13344.6 KFY05082.1 - 2.2e-21 75.8 0.0 5.3e-21 74.6 0.0 1.7 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 KFY05082.1 - 1.9e-16 59.9 0.0 4.1e-16 58.8 0.0 1.6 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.26 KFY05082.1 - 3.2e-06 27.6 0.0 1.5 9.0 0.0 3.9 2 1 2 4 4 4 3 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 KFY05082.1 - 0.00066 19.8 0.0 0.84 9.7 0.0 2.6 2 1 1 3 3 3 2 Haloacid dehalogenase-like hydrolase SIP1 PF04938.12 KFY05083.1 - 3.7e-13 49.7 0.0 2.5e-11 43.7 0.0 2.3 2 0 0 2 2 2 1 Survival motor neuron (SMN) interacting protein 1 (SIP1) eIF3_N PF09440.10 KFY05083.1 - 0.21 12.0 2.8 0.58 10.6 1.5 2.2 2 0 0 2 2 2 0 eIF3 subunit 6 N terminal domain DUF3280 PF11684.8 KFY05083.1 - 0.36 11.2 5.4 1 9.8 5.4 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2380) PTPRCAP PF15713.5 KFY05083.1 - 5 7.4 14.3 5.3 7.3 3.6 2.6 2 0 0 2 2 2 0 Protein tyrosine phosphatase receptor type C-associated ABC_tran PF00005.27 KFY05084.1 - 1.4e-17 64.5 0.1 3e-17 63.4 0.1 1.6 1 0 0 1 1 1 1 ABC transporter AAA_29 PF13555.6 KFY05084.1 - 0.006 16.3 0.0 0.015 15.1 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 KFY05084.1 - 0.013 15.4 0.0 0.023 14.6 0.0 1.3 1 0 0 1 1 1 0 RsgA GTPase AAA_22 PF13401.6 KFY05084.1 - 0.02 15.1 0.0 0.049 13.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.6 KFY05084.1 - 0.02 14.9 0.0 0.24 11.4 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 KFY05084.1 - 0.03 14.9 0.0 0.07 13.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain ATPase_2 PF01637.18 KFY05084.1 - 0.03 14.2 0.0 0.051 13.5 0.0 1.3 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea NACHT PF05729.12 KFY05084.1 - 0.045 13.7 0.0 0.082 12.8 0.0 1.4 1 0 0 1 1 1 0 NACHT domain Rad17 PF03215.15 KFY05084.1 - 0.069 13.1 0.0 0.14 12.1 0.0 1.5 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_16 PF13191.6 KFY05084.1 - 0.078 13.4 0.0 0.12 12.7 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain AAA_25 PF13481.6 KFY05084.1 - 0.084 12.4 0.0 0.14 11.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_21 PF13304.6 KFY05084.1 - 0.12 12.2 0.1 0.17 11.7 0.1 1.2 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_28 PF13521.6 KFY05084.1 - 0.14 12.4 0.0 0.23 11.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain Aminotran_1_2 PF00155.21 KFY05085.1 - 4.3e-39 134.7 0.0 1e-38 133.5 0.0 1.5 1 1 1 2 2 2 1 Aminotransferase class I and II Aminotran_MocR PF12897.7 KFY05085.1 - 1.1e-06 27.8 0.0 2e-06 26.9 0.0 1.4 1 1 0 1 1 1 1 Alanine-glyoxylate amino-transferase Cys_Met_Meta_PP PF01053.20 KFY05085.1 - 1.8e-06 26.8 0.0 3e-06 26.0 0.0 1.3 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.19 KFY05085.1 - 6.4e-06 25.4 0.0 1e-05 24.7 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 KFY05085.1 - 0.00016 21.0 0.0 0.0003 20.2 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase Alliinase_C PF04864.13 KFY05085.1 - 0.00095 18.1 0.1 0.0023 16.9 0.1 1.6 1 1 0 1 1 1 1 Allinase DnaB_2 PF07261.11 KFY05085.1 - 0.057 13.2 0.0 21 4.9 0.0 3.2 3 0 0 3 3 3 0 Replication initiation and membrane attachment DUF2300 PF10062.9 KFY05085.1 - 0.066 13.3 0.0 0.14 12.2 0.0 1.5 1 0 0 1 1 1 0 Predicted secreted protein (DUF2300) SET PF00856.28 KFY05086.1 - 1.2e-08 35.6 0.2 9e-08 32.7 0.2 2.0 1 1 0 1 1 1 1 SET domain MRP-S26 PF14943.6 KFY05087.1 - 0.028 14.3 4.1 1.6 8.6 0.1 2.2 2 0 0 2 2 2 0 Mitochondrial ribosome subunit S26 NGP1NT PF08153.12 KFY05088.1 - 3.3e-46 156.6 0.1 5.4e-46 156.0 0.1 1.3 1 0 0 1 1 1 1 NGP1NT (NUC091) domain MMR_HSR1 PF01926.23 KFY05088.1 - 7.8e-17 61.4 0.0 5.1e-13 49.1 0.0 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase FeoB_N PF02421.18 KFY05088.1 - 0.00023 20.7 0.1 0.0011 18.5 0.0 1.9 2 0 0 2 2 2 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 KFY05088.1 - 0.00082 19.3 0.0 0.0017 18.3 0.0 1.5 1 0 0 1 1 1 1 RsgA GTPase Arf PF00025.21 KFY05088.1 - 0.0016 17.9 0.0 0.14 11.6 0.0 2.3 2 0 0 2 2 2 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 KFY05088.1 - 0.0071 15.9 0.0 0.32 10.5 0.0 2.9 3 0 0 3 3 3 1 Elongation factor Tu GTP binding domain Dynamin_N PF00350.23 KFY05088.1 - 0.017 15.2 5.4 1.3 9.1 0.0 4.0 3 1 1 4 4 4 0 Dynamin family AAA_16 PF13191.6 KFY05088.1 - 0.13 12.6 0.8 0.97 9.8 0.0 2.6 3 0 0 3 3 3 0 AAA ATPase domain HBS1_N PF08938.10 KFY05088.1 - 1.4 9.3 12.9 3.6 8.0 0.1 2.5 2 0 0 2 2 2 0 HBS1 N-terminus DNA_pol_phi PF04931.13 KFY05088.1 - 1.4 6.9 18.6 2.1 6.3 18.6 1.2 1 0 0 1 1 1 0 DNA polymerase phi Merozoite_SPAM PF07133.11 KFY05088.1 - 5.9 6.8 24.4 1.3 9.0 20.9 1.6 2 0 0 2 2 2 0 Merozoite surface protein (SPAM) AT_hook PF02178.19 KFY05089.1 - 7.8 6.7 15.1 0.2 11.6 5.0 3.9 2 0 0 2 2 2 0 AT hook motif DUF202 PF02656.15 KFY05090.1 - 0.14 12.6 3.2 0.22 12.0 0.1 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF202) AAA PF00004.29 KFY05091.1 - 9.6e-20 71.3 0.0 5.9e-17 62.3 0.0 3.2 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) NACHT PF05729.12 KFY05091.1 - 1.3e-08 34.9 0.3 3e-05 24.0 0.0 3.3 3 1 0 3 3 2 2 NACHT domain AAA_22 PF13401.6 KFY05091.1 - 5.2e-08 33.3 0.0 0.0022 18.2 0.0 3.3 3 0 0 3 3 2 2 AAA domain AAA_16 PF13191.6 KFY05091.1 - 6.5e-08 33.2 0.0 0.014 15.8 0.0 3.3 3 0 0 3 3 3 2 AAA ATPase domain AAA_18 PF13238.6 KFY05091.1 - 2.5e-06 28.0 0.0 0.015 15.9 0.0 2.9 2 0 0 2 2 2 2 AAA domain RNA_helicase PF00910.22 KFY05091.1 - 4.1e-05 23.9 0.2 0.062 13.7 0.1 2.8 2 0 0 2 2 2 1 RNA helicase AAA_30 PF13604.6 KFY05091.1 - 0.00011 22.0 0.1 0.019 14.7 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 KFY05091.1 - 0.00066 19.4 1.3 0.0087 15.8 0.1 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_14 PF13173.6 KFY05091.1 - 0.00087 19.3 0.0 3 7.9 0.0 3.2 2 1 1 3 3 3 2 AAA domain Transposase_mut PF00872.18 KFY05091.1 - 0.0011 17.9 0.3 0.0019 17.1 0.3 1.3 1 0 0 1 1 1 1 Transposase, Mutator family AAA_5 PF07728.14 KFY05091.1 - 0.0015 18.5 0.2 0.25 11.4 0.0 3.1 3 0 0 3 3 2 1 AAA domain (dynein-related subfamily) NB-ARC PF00931.22 KFY05091.1 - 0.0018 17.5 0.1 1 8.5 0.0 2.5 2 0 0 2 2 2 2 NB-ARC domain ABC_tran PF00005.27 KFY05091.1 - 0.0033 17.9 0.1 0.068 13.7 0.0 3.0 3 0 0 3 3 3 1 ABC transporter ATPase PF06745.13 KFY05091.1 - 0.0047 16.3 2.2 0.5 9.7 0.3 3.2 3 0 0 3 3 3 1 KaiC Zeta_toxin PF06414.12 KFY05091.1 - 0.0054 16.0 0.0 3.4 6.9 0.0 2.4 2 0 0 2 2 2 2 Zeta toxin SesA PF17107.5 KFY05091.1 - 0.0059 16.8 0.1 0.023 14.9 0.1 2.1 1 0 0 1 1 1 1 N-terminal domain on NACHT_NTPase and P-loop NTPases NTPase_1 PF03266.15 KFY05091.1 - 0.011 15.7 0.0 4.2 7.3 0.0 3.0 3 0 0 3 3 3 0 NTPase RuvB_N PF05496.12 KFY05091.1 - 0.013 15.3 0.1 0.052 13.3 0.0 2.0 3 0 0 3 3 1 0 Holliday junction DNA helicase RuvB P-loop domain TsaE PF02367.17 KFY05091.1 - 0.017 15.1 0.0 8.8 6.3 0.0 2.6 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_17 PF13207.6 KFY05091.1 - 0.019 15.4 0.1 2.2 8.7 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 KFY05091.1 - 0.031 14.0 0.1 3 7.5 0.1 2.4 2 0 0 2 2 2 0 AAA domain ATPase_2 PF01637.18 KFY05091.1 - 0.033 14.1 0.0 0.16 11.9 0.0 2.1 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea Rad17 PF03215.15 KFY05091.1 - 0.061 13.2 0.0 2.8 7.8 0.0 2.6 2 0 0 2 2 2 0 Rad17 P-loop domain RsgA_GTPase PF03193.16 KFY05091.1 - 0.076 12.9 0.0 0.73 9.7 0.0 2.3 2 0 0 2 2 2 0 RsgA GTPase AAA_19 PF13245.6 KFY05091.1 - 0.084 13.2 0.0 18 5.6 0.0 2.6 2 0 0 2 2 2 0 AAA domain DUF2075 PF09848.9 KFY05091.1 - 0.1 11.8 0.0 12 5.0 0.0 2.4 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA_33 PF13671.6 KFY05091.1 - 0.1 12.7 0.1 12 6.0 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 KFY05091.1 - 0.11 12.0 0.0 4.9 6.6 0.0 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_28 PF13521.6 KFY05091.1 - 0.16 12.2 0.0 4.3 7.5 0.0 2.6 2 0 0 2 2 2 0 AAA domain ATP_bind_1 PF03029.17 KFY05091.1 - 0.19 11.5 0.2 0.61 9.8 0.1 1.9 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein DUF87 PF01935.17 KFY05091.1 - 0.78 9.8 5.4 3.4 7.7 0.2 2.9 1 1 1 2 2 2 0 Helicase HerA, central domain Methyltransf_23 PF13489.6 KFY05093.1 - 1.3e-22 80.4 0.0 1.9e-22 79.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 KFY05093.1 - 8.2e-14 52.1 0.0 1.7e-13 51.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 KFY05093.1 - 7.1e-13 49.0 0.0 1.2e-12 48.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KFY05093.1 - 2.3e-09 37.9 0.0 1.2e-08 35.6 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KFY05093.1 - 4.6e-09 36.2 0.0 1.3e-07 31.6 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.19 KFY05093.1 - 0.00091 19.4 0.0 0.0017 18.5 0.0 1.4 1 0 0 1 1 1 1 FtsJ-like methyltransferase Ubie_methyltran PF01209.18 KFY05093.1 - 0.0023 17.3 0.0 0.02 14.2 0.0 2.2 2 1 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_4 PF02390.17 KFY05093.1 - 0.0052 16.3 0.0 0.018 14.5 0.0 1.8 2 0 0 2 2 2 1 Putative methyltransferase MTS PF05175.14 KFY05093.1 - 0.008 15.7 0.0 0.059 12.9 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase small domain PrmA PF06325.13 KFY05093.1 - 0.033 13.6 0.0 0.056 12.8 0.0 1.4 1 1 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_2 PF00891.18 KFY05093.1 - 0.12 11.6 0.0 0.33 10.2 0.0 1.7 1 1 0 1 1 1 0 O-methyltransferase domain CMAS PF02353.20 KFY05093.1 - 0.13 11.5 0.0 0.37 10.0 0.0 1.7 2 1 0 2 2 2 0 Mycolic acid cyclopropane synthetase Glyco_hydro_7 PF00840.20 KFY05095.1 - 2.9e-136 454.7 5.5 5.4e-135 450.5 5.5 2.0 1 1 0 1 1 1 1 Glycosyl hydrolase family 7 CBM_20 PF00686.19 KFY05097.1 - 8.6e-33 112.1 0.7 1.4e-32 111.4 0.7 1.3 1 0 0 1 1 1 1 Starch binding domain LPMO_10 PF03067.15 KFY05097.1 - 1.2e-09 39.2 1.8 2e-09 38.4 1.8 1.4 1 0 0 1 1 1 1 Lytic polysaccharide mono-oxygenase, cellulose-degrading PAD PF03068.15 KFY05100.1 - 3.2e-99 332.6 0.0 2.6e-72 244.0 0.0 2.0 1 1 1 2 2 2 2 Protein-arginine deiminase (PAD) Inhibitor_I66 PF16850.5 KFY05101.1 - 9.3e-26 90.4 0.0 1.1e-25 90.2 0.0 1.0 1 0 0 1 1 1 1 Peptidase inhibitor I66 Fungal_trans_2 PF11951.8 KFY05102.1 - 1.8e-29 102.7 4.5 2.2e-29 102.5 4.5 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KFY05102.1 - 5.6e-05 23.2 8.8 0.00013 22.0 8.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ras PF00071.22 KFY05103.1 - 1.8e-12 47.1 0.0 4.8e-12 45.8 0.0 1.6 1 1 0 1 1 1 1 Ras family Roc PF08477.13 KFY05103.1 - 0.015 15.5 0.0 0.023 14.9 0.0 1.4 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase MeaB PF03308.16 KFY05103.1 - 0.053 12.5 0.4 6.5 5.7 0.2 2.1 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB MMR_HSR1 PF01926.23 KFY05103.1 - 0.085 12.9 0.1 0.17 12.0 0.1 1.5 2 0 0 2 2 2 0 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KFY05103.1 - 0.13 12.1 0.0 0.61 10.0 0.1 1.9 2 0 0 2 2 2 0 RsgA GTPase AA_permease_2 PF13520.6 KFY05104.1 - 2e-80 270.7 22.5 3.5e-80 269.9 22.5 1.4 1 0 0 1 1 1 1 Amino acid permease Lipase_GDSL_2 PF13472.6 KFY05105.1 - 0.0007 20.0 0.0 0.0011 19.4 0.0 1.3 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 KFY05105.1 - 0.0013 18.7 0.5 0.0019 18.2 0.5 1.3 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase AA_permease_2 PF13520.6 KFY05106.1 - 8.4e-56 189.6 53.1 1e-55 189.3 53.1 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KFY05106.1 - 6.5e-18 64.6 40.1 8.5e-18 64.2 40.1 1.1 1 0 0 1 1 1 1 Amino acid permease Cu_amine_oxid PF01179.20 KFY05107.1 - 8.1e-155 515.7 0.0 1.1e-154 515.3 0.0 1.2 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN3 PF02728.16 KFY05107.1 - 2.6e-20 72.7 0.0 5.3e-20 71.7 0.0 1.5 1 0 0 1 1 1 1 Copper amine oxidase, N3 domain Cu_amine_oxidN2 PF02727.16 KFY05107.1 - 5.6e-13 48.9 0.1 1.3e-12 47.8 0.1 1.6 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain FSH1 PF03959.13 KFY05108.1 - 6e-25 88.2 0.0 2.2e-24 86.3 0.0 1.7 1 1 0 1 1 1 1 Serine hydrolase (FSH1) FhuF PF06276.12 KFY05109.1 - 8.3e-18 65.3 0.0 1.4e-17 64.6 0.0 1.3 1 0 0 1 1 1 1 Ferric iron reductase FhuF-like transporter IucA_IucC PF04183.12 KFY05109.1 - 1.4e-17 64.1 0.9 1.4e-15 57.5 0.1 2.3 2 0 0 2 2 2 2 IucA / IucC family TauD PF02668.16 KFY05110.1 - 2.8e-28 99.5 0.0 4.5e-28 98.8 0.0 1.3 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family CsiD PF08943.10 KFY05110.1 - 0.0087 15.2 0.0 0.013 14.6 0.0 1.2 1 0 0 1 1 1 1 CsiD DUF4727 PF15856.5 KFY05110.1 - 0.072 12.7 0.0 0.12 12.0 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4727) Peptidase_S8 PF00082.22 KFY05111.1 - 4.1e-35 121.5 10.1 1e-34 120.2 10.1 1.5 1 1 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.16 KFY05111.1 - 2.8e-09 37.5 0.6 5.4e-09 36.6 0.6 1.5 1 0 0 1 1 1 1 Peptidase inhibitor I9 Uds1 PF15456.6 KFY05112.1 - 5.8e-40 136.5 1.7 5.8e-40 136.5 1.7 5.1 2 1 2 5 5 5 1 Up-regulated During Septation HR1 PF02185.16 KFY05112.1 - 4.7e-06 26.6 1.0 4.7e-06 26.6 1.0 6.8 5 1 3 8 8 8 1 Hr1 repeat Spc7 PF08317.11 KFY05112.1 - 0.00099 18.1 20.9 0.00099 18.1 20.9 4.4 4 1 2 6 6 6 2 Spc7 kinetochore protein DUF4407 PF14362.6 KFY05112.1 - 0.038 13.3 61.4 0.034 13.5 21.1 4.2 2 1 2 4 4 4 0 Domain of unknown function (DUF4407) Fez1 PF06818.15 KFY05112.1 - 0.31 11.5 54.4 6.8 7.1 0.4 4.5 2 1 3 5 5 5 0 Fez1 HMMR_N PF15905.5 KFY05112.1 - 2.2 7.7 46.4 0.43 10.0 30.8 4.4 2 1 2 4 4 4 0 Hyaluronan mediated motility receptor N-terminal DUF16 PF01519.16 KFY05112.1 - 4.2 7.9 27.1 0.09 13.3 1.4 5.4 2 1 3 5 5 5 0 Protein of unknown function DUF16 Pex19 PF04614.12 KFY05114.1 - 1.9e-74 250.5 13.2 1.9e-74 250.5 13.2 2.3 2 1 0 2 2 2 1 Pex19 protein family LUD_dom PF02589.15 KFY05114.1 - 0.00019 21.2 0.7 0.0003 20.6 0.7 1.3 1 0 0 1 1 1 1 LUD domain EspB PF05802.11 KFY05114.1 - 0.016 15.2 5.9 0.89 9.5 2.6 2.6 2 1 0 2 2 2 0 Enterobacterial EspB protein Vps4_C PF09336.10 KFY05114.1 - 0.025 14.6 0.1 0.093 12.7 0.1 2.1 1 0 0 1 1 1 0 Vps4 C terminal oligomerisation domain GlutR_dimer PF00745.20 KFY05114.1 - 0.1 13.1 1.0 0.28 11.7 1.0 1.9 1 0 0 1 1 1 0 Glutamyl-tRNAGlu reductase, dimerisation domain dsDNA_bind PF01984.20 KFY05114.1 - 0.47 10.7 3.1 2.3 8.5 1.6 2.5 1 1 1 2 2 2 0 Double-stranded DNA-binding domain DUF573 PF04504.14 KFY05114.1 - 0.59 10.8 2.9 4.1 8.1 0.2 2.8 3 1 0 3 3 3 0 Protein of unknown function, DUF573 FliE PF02049.18 KFY05114.1 - 0.89 9.7 11.5 0.088 13.0 3.0 3.4 2 1 2 4 4 4 0 Flagellar hook-basal body complex protein FliE Auxin_canalis PF05703.11 KFY05115.1 - 0.023 14.6 1.2 0.023 14.6 1.2 1.4 2 0 0 2 2 2 0 Auxin canalisation Ribosomal_60s PF00428.19 KFY05116.1 - 3.6e-25 88.4 8.5 5.2e-25 87.9 8.5 1.2 1 0 0 1 1 1 1 60s Acidic ribosomal protein FERM_F1 PF18379.1 KFY05116.1 - 0.15 12.1 0.0 0.21 11.6 0.0 1.3 1 0 0 1 1 1 0 FERM F1 ubiquitin-like domain DUF2408 PF10303.9 KFY05117.1 - 5.1e-42 143.6 1.0 2.1e-24 86.6 0.1 4.9 3 2 1 4 4 4 3 Protein of unknown function (DUF2408) PolyG_pol PF01518.16 KFY05117.1 - 0.0013 17.6 0.1 0.0021 16.8 0.1 1.2 1 0 0 1 1 1 1 Sigma NS protein DUF1664 PF07889.12 KFY05117.1 - 0.0029 17.6 0.3 0.034 14.2 0.0 2.7 3 0 0 3 3 3 1 Protein of unknown function (DUF1664) DUF2920 PF11144.8 KFY05117.1 - 0.019 14.1 0.1 29 3.7 0.0 3.4 4 0 0 4 4 4 0 Protein of unknown function (DUF2920) Laminin_II PF06009.12 KFY05117.1 - 0.022 14.8 1.5 0.089 12.8 0.1 2.5 2 1 0 2 2 2 0 Laminin Domain II DUF2087 PF09860.9 KFY05117.1 - 0.047 13.8 0.0 3 8.1 0.0 3.3 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2087) Phage_term_smal PF05944.12 KFY05117.1 - 0.05 13.6 0.0 0.92 9.5 0.0 2.5 3 0 0 3 3 3 0 Phage small terminase subunit DUF4200 PF13863.6 KFY05117.1 - 0.053 13.9 0.7 0.12 12.8 0.6 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4200) Spc7 PF08317.11 KFY05117.1 - 0.065 12.1 1.8 0.24 10.2 1.8 2.0 1 1 0 1 1 1 0 Spc7 kinetochore protein PTPA PF03095.15 KFY05117.1 - 0.079 12.4 0.1 0.39 10.1 0.1 2.0 1 1 0 1 1 1 0 Phosphotyrosyl phosphate activator (PTPA) protein COG6 PF06419.11 KFY05117.1 - 0.097 10.9 3.3 0.078 11.2 0.7 2.0 2 1 0 2 2 2 0 Conserved oligomeric complex COG6 ATR13 PF16829.5 KFY05117.1 - 0.11 12.9 0.0 0.4 11.1 0.0 2.0 2 0 0 2 2 2 0 Avirulence protein ATR13, RxLR effector Helo_like_N PF17111.5 KFY05117.1 - 0.16 11.3 2.5 0.56 9.5 2.5 1.9 1 1 0 1 1 1 0 Fungal N-terminal domain of STAND proteins Syntaxin-6_N PF09177.11 KFY05117.1 - 0.2 12.2 1.5 0.6 10.7 0.5 2.4 3 1 0 3 3 2 0 Syntaxin 6, N-terminal Cut8 PF08559.10 KFY05118.1 - 6.5e-82 274.8 0.0 8.5e-82 274.4 0.0 1.1 1 0 0 1 1 1 1 Cut8, nuclear proteasome tether protein DUF4953 PF16313.5 KFY05118.1 - 0.0036 16.6 0.0 0.018 14.2 0.0 1.9 2 0 0 2 2 2 1 Met-zincin DUF3435 PF11917.8 KFY05124.1 - 1.8e-46 158.9 0.1 2.2e-46 158.6 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3435) Glutaredoxin PF00462.24 KFY05126.1 - 2.9e-18 65.8 0.0 4.5e-18 65.2 0.0 1.3 1 0 0 1 1 1 1 Glutaredoxin CYSTM PF12734.7 KFY05127.1 - 4.4e-12 46.1 24.2 4.4e-12 46.1 24.2 4.5 1 1 2 3 3 3 1 Cysteine-rich TM module stress tolerance Pex14_N PF04695.13 KFY05127.1 - 0.53 10.9 6.2 0.59 10.8 6.2 1.1 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region A_deaminase PF00962.22 KFY05128.1 - 7.7e-123 410.0 0.1 1.1e-122 409.5 0.1 1.2 1 0 0 1 1 1 1 Adenosine/AMP deaminase UAA PF08449.11 KFY05129.1 - 3.8e-100 335.0 7.2 4.5e-100 334.7 7.2 1.0 1 0 0 1 1 1 1 UAA transporter family Nuc_sug_transp PF04142.15 KFY05129.1 - 4e-06 26.2 7.1 7.6e-06 25.3 7.1 1.4 1 1 0 1 1 1 1 Nucleotide-sugar transporter Tetraspanin PF00335.20 KFY05129.1 - 0.021 14.5 0.1 0.021 14.5 0.1 2.2 2 0 0 2 2 2 0 Tetraspanin family TMEM100 PF16311.5 KFY05129.1 - 0.025 14.1 0.1 0.051 13.2 0.1 1.4 1 0 0 1 1 1 0 Transmembrane protein 100 Pox_A14 PF05767.12 KFY05129.1 - 0.034 14.3 0.3 0.11 12.7 0.0 2.0 2 0 0 2 2 2 0 Poxvirus virion envelope protein A14 Romo1 PF10247.9 KFY05129.1 - 0.034 14.5 2.2 7.9 6.9 0.4 2.9 2 0 0 2 2 2 0 Reactive mitochondrial oxygen species modulator 1 EamA PF00892.20 KFY05129.1 - 0.11 12.7 30.5 0.19 11.9 10.9 4.0 2 2 1 3 3 3 0 EamA-like transporter family TMEM234 PF10639.9 KFY05129.1 - 0.15 12.1 2.8 0.91 9.6 0.4 2.3 2 0 0 2 2 2 0 Putative transmembrane family 234 LSM PF01423.22 KFY05131.1 - 2.4e-18 65.6 0.5 3.1e-18 65.2 0.5 1.1 1 0 0 1 1 1 1 LSM domain Hfq PF17209.3 KFY05131.1 - 0.011 15.4 0.1 0.017 14.8 0.1 1.3 1 0 0 1 1 1 0 Hfq protein SM-ATX PF14438.6 KFY05131.1 - 0.083 13.0 0.1 0.1 12.7 0.1 1.3 1 0 0 1 1 1 0 Ataxin 2 SM domain MFS_1 PF07690.16 KFY05134.1 - 2.8e-35 121.9 69.4 1.1e-31 110.0 53.3 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Epimerase PF01370.21 KFY05134.1 - 2.2e-08 33.9 0.0 5.9e-08 32.5 0.0 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KFY05134.1 - 5.9e-07 28.8 0.0 9.7e-07 28.1 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 KFY05134.1 - 5.1e-05 22.6 1.1 0.0001 21.6 0.1 1.9 3 0 0 3 3 3 1 Male sterility protein GDP_Man_Dehyd PF16363.5 KFY05134.1 - 0.00035 20.1 0.0 0.00066 19.2 0.0 1.4 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase NmrA PF05368.13 KFY05134.1 - 0.034 13.7 0.4 0.092 12.3 0.4 1.8 1 0 0 1 1 1 0 NmrA-like family Abhydrolase_6 PF12697.7 KFY05135.1 - 4.9e-17 63.3 0.0 8.2e-17 62.5 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 KFY05135.1 - 6e-15 55.6 0.3 1.2e-14 54.6 0.3 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 KFY05135.1 - 0.00044 19.6 0.0 0.029 13.6 0.0 2.2 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_2 PF02230.16 KFY05135.1 - 0.0058 16.5 0.0 0.47 10.2 0.0 2.5 3 0 0 3 3 3 1 Phospholipase/Carboxylesterase FAD_binding_3 PF01494.19 KFY05136.1 - 1.5e-15 57.3 0.0 1.5e-14 54.1 0.0 2.0 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 KFY05136.1 - 0.001 19.3 0.0 0.003 17.8 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 KFY05136.1 - 0.058 12.4 0.7 1.8 7.6 0.1 2.4 3 0 0 3 3 3 0 Lycopene cyclase protein DUF1460 PF07313.12 KFY05136.1 - 0.11 11.8 0.2 0.23 10.8 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1460) Ank_2 PF12796.7 KFY05137.1 - 1.8e-61 204.7 0.2 1.7e-18 67.0 0.0 3.8 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KFY05137.1 - 3.1e-39 132.9 0.4 2e-08 34.6 0.0 6.0 1 1 5 6 6 6 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFY05137.1 - 5.8e-39 127.7 0.0 3.2e-05 24.0 0.0 7.4 7 0 0 7 7 7 6 Ankyrin repeat Ank PF00023.30 KFY05137.1 - 1.2e-38 129.8 0.0 6.8e-05 23.1 0.0 6.7 7 0 0 7 7 7 6 Ankyrin repeat Ank_5 PF13857.6 KFY05137.1 - 2.8e-30 104.0 0.1 1.6e-06 28.3 0.0 5.4 2 1 3 5 5 5 5 Ankyrin repeats (many copies) VWA_3_C PF18571.1 KFY05137.1 - 7.5e-05 22.5 9.6 0.21 11.5 0.1 5.4 6 0 0 6 6 6 2 von Willebrand factor type A C-terminal domain Cullin PF00888.22 KFY05139.1 - 9.4e-196 652.1 11.6 1.2e-195 651.8 11.6 1.1 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 KFY05139.1 - 7e-24 83.7 4.4 7e-24 83.7 4.4 2.5 3 0 0 3 3 3 1 Cullin protein neddylation domain AnfG_VnfG PF03139.15 KFY05139.1 - 0.012 15.7 2.5 0.21 11.7 0.9 3.0 2 0 0 2 2 2 0 Vanadium/alternative nitrogenase delta subunit TatD_DNase PF01026.21 KFY05140.1 - 4.6e-32 111.4 0.0 8.1e-32 110.6 0.0 1.4 1 0 0 1 1 1 1 TatD related DNase RGP PF03214.13 KFY05140.1 - 0.083 12.0 0.0 2.3 7.3 0.0 2.1 2 0 0 2 2 2 0 Reversibly glycosylated polypeptide ResIII PF04851.15 KFY05141.1 - 2.6e-21 76.4 0.0 8.2e-21 74.7 0.0 1.9 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 KFY05141.1 - 9.9e-15 54.8 0.0 3.8e-13 49.8 0.0 2.5 2 1 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 KFY05141.1 - 8.1e-10 38.7 0.0 4.2e-09 36.4 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase SWI2_SNF2 PF18766.1 KFY05141.1 - 0.00037 20.2 0.0 0.00082 19.1 0.0 1.5 1 0 0 1 1 1 1 SWI2/SNF2 ATPase DUF2075 PF09848.9 KFY05141.1 - 0.049 12.9 0.0 0.097 11.9 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) DUF2034 PF10356.9 KFY05142.1 - 6.8e-31 107.1 0.0 9.1e-15 54.6 0.0 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF2034) Mrr_cat PF04471.12 KFY05142.1 - 3.4e-09 36.7 0.0 4.8e-09 36.2 0.0 1.2 1 0 0 1 1 1 1 Restriction endonuclease DUF4365 PF14280.6 KFY05142.1 - 0.008 16.1 0.0 0.013 15.5 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4365) Med21 PF11221.8 KFY05143.1 - 7.2e-46 156.0 4.4 8.3e-46 155.8 4.4 1.0 1 0 0 1 1 1 1 Subunit 21 of Mediator complex GAS PF13851.6 KFY05143.1 - 0.0012 18.3 6.1 0.09 12.1 4.7 2.1 2 0 0 2 2 2 2 Growth-arrest specific micro-tubule binding BRE1 PF08647.11 KFY05143.1 - 0.0037 17.3 3.7 0.0037 17.3 3.7 1.8 2 0 0 2 2 2 1 BRE1 E3 ubiquitin ligase Med9 PF07544.13 KFY05143.1 - 0.0049 16.9 5.1 0.0074 16.3 3.7 2.1 2 1 0 2 2 2 1 RNA polymerase II transcription mediator complex subunit 9 HMMR_N PF15905.5 KFY05143.1 - 0.0065 16.0 5.8 0.0086 15.6 5.8 1.2 1 0 0 1 1 1 1 Hyaluronan mediated motility receptor N-terminal Herpes_UL6 PF01763.16 KFY05143.1 - 0.048 12.2 2.1 0.062 11.8 2.1 1.1 1 0 0 1 1 1 0 Herpesvirus UL6 like DUF4574 PF15141.6 KFY05143.1 - 0.13 12.2 1.6 0.22 11.4 1.6 1.5 1 0 0 1 1 1 0 Ubiquinol-cytochrome-c reductase complex assembly factor 3 FUSC PF04632.12 KFY05143.1 - 2.4 6.6 4.2 0.47 8.9 1.3 1.3 2 0 0 2 2 2 0 Fusaric acid resistance protein family Pkinase PF00069.25 KFY05146.1 - 2.1e-67 227.3 0.0 2.6e-67 227.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFY05146.1 - 1e-31 110.2 0.0 1.3e-31 109.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 KFY05146.1 - 8e-06 25.0 0.1 1e-05 24.6 0.1 1.1 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 KFY05146.1 - 0.00011 21.6 0.1 0.00035 20.0 0.1 1.7 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 KFY05146.1 - 0.00067 19.7 0.0 0.0011 19.0 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.6 KFY05146.1 - 0.0016 17.8 0.0 0.05 12.9 0.0 2.3 1 1 1 2 2 2 1 Kinase-like FTA2 PF13095.6 KFY05146.1 - 0.011 15.4 0.0 0.022 14.4 0.0 1.5 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 RIO1 PF01163.22 KFY05146.1 - 0.024 14.2 0.0 0.043 13.4 0.0 1.4 1 0 0 1 1 1 0 RIO1 family WD40 PF00400.32 KFY05148.1 - 4.4e-35 119.1 19.4 2.4e-07 31.3 0.0 12.3 13 0 0 13 13 13 7 WD domain, G-beta repeat WHIM1 PF15612.6 KFY05148.1 - 1.3e-05 24.6 0.0 3.3e-05 23.3 0.0 1.7 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 1 Nop14 PF04147.12 KFY05148.1 - 6.5 4.8 11.0 10 4.2 11.0 1.2 1 0 0 1 1 1 0 Nop14-like family ABC_tran PF00005.27 KFY05149.1 - 1.1e-16 61.6 0.0 3.3e-16 60.1 0.0 1.8 1 1 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 KFY05149.1 - 9.7e-11 42.0 2.4 0.00015 21.7 0.1 2.1 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 KFY05149.1 - 0.00018 21.0 0.0 0.52 9.7 0.0 2.1 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 KFY05149.1 - 0.00047 19.8 0.4 0.0011 18.7 0.1 1.7 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_23 PF13476.6 KFY05149.1 - 0.0026 18.3 0.0 0.0053 17.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_15 PF13175.6 KFY05149.1 - 0.0029 17.4 0.0 0.0046 16.7 0.0 1.2 1 0 0 1 1 1 1 AAA ATPase domain DUF3584 PF12128.8 KFY05149.1 - 0.0083 13.7 0.3 0.011 13.3 0.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) AAA_16 PF13191.6 KFY05149.1 - 0.0099 16.3 0.2 0.017 15.5 0.2 1.5 1 1 0 1 1 1 1 AAA ATPase domain PduV-EutP PF10662.9 KFY05149.1 - 0.015 15.0 0.1 0.024 14.4 0.1 1.2 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_25 PF13481.6 KFY05149.1 - 0.032 13.8 0.1 0.046 13.3 0.1 1.4 1 1 0 1 1 1 0 AAA domain DLIC PF05783.11 KFY05149.1 - 0.067 12.0 0.0 0.09 11.6 0.0 1.2 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) AAA_33 PF13671.6 KFY05149.1 - 0.071 13.3 0.3 0.15 12.2 0.1 1.6 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 KFY05149.1 - 0.083 13.2 0.5 0.24 11.6 0.1 1.9 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 KFY05149.1 - 0.12 12.3 0.2 0.22 11.4 0.2 1.4 1 0 0 1 1 1 0 NACHT domain AAA_5 PF07728.14 KFY05149.1 - 0.16 12.0 0.8 0.83 9.6 0.2 2.1 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) RsgA_GTPase PF03193.16 KFY05149.1 - 0.2 11.6 0.1 0.33 10.8 0.1 1.3 1 0 0 1 1 1 0 RsgA GTPase AAA_13 PF13166.6 KFY05149.1 - 0.21 10.2 0.1 0.29 9.7 0.1 1.1 1 0 0 1 1 1 0 AAA domain DUF1770 PF08589.10 KFY05150.1 - 2e-34 118.5 1.7 2e-34 118.5 0.9 1.4 2 0 0 2 2 2 1 Fungal protein of unknown function (DUF1770) DER1 PF04511.15 KFY05151.1 - 3.3e-24 85.9 5.4 3.9e-24 85.7 5.4 1.0 1 0 0 1 1 1 1 Der1-like family DUF3384 PF11864.8 KFY05152.1 - 8.6e-128 427.2 0.1 1.7e-127 426.3 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3384) Rap_GAP PF02145.15 KFY05152.1 - 7.2e-53 178.9 0.0 1.2e-52 178.1 0.0 1.4 1 0 0 1 1 1 1 Rap/ran-GAP Tuberin PF03542.16 KFY05152.1 - 8.5e-41 140.2 0.9 7.9e-37 127.2 0.0 3.0 3 0 0 3 3 3 2 Tuberin Cse1 PF08506.10 KFY05153.1 - 4.7e-156 519.3 0.6 7e-156 518.7 0.6 1.3 1 0 0 1 1 1 1 Cse1 CAS_CSE1 PF03378.15 KFY05153.1 - 4.6e-106 355.0 1.3 1.6e-105 353.1 0.2 2.4 3 0 0 3 3 3 1 CAS/CSE protein, C-terminus IBN_N PF03810.19 KFY05153.1 - 1.3e-12 47.4 0.0 4.5e-12 45.7 0.0 2.0 1 0 0 1 1 1 1 Importin-beta N-terminal domain Xpo1 PF08389.12 KFY05153.1 - 0.0092 16.1 7.3 0.49 10.4 0.0 5.7 6 1 0 6 6 6 1 Exportin 1-like protein OmpH PF03938.14 KFY05153.1 - 0.26 11.6 1.1 0.94 9.8 0.0 2.3 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) Methyltransf_23 PF13489.6 KFY05157.1 - 9.5e-19 67.8 0.0 4.6e-18 65.6 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 KFY05157.1 - 2.7e-07 31.2 0.0 8.2e-07 29.7 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 KFY05157.1 - 0.00016 21.5 0.0 0.0049 16.7 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KFY05157.1 - 0.0003 21.5 0.0 0.0038 17.9 0.0 2.7 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 KFY05157.1 - 0.00087 19.9 0.0 0.002 18.7 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.19 KFY05157.1 - 0.017 15.2 0.0 0.079 13.1 0.0 1.9 2 0 0 2 2 2 0 FtsJ-like methyltransferase Methyltransf_4 PF02390.17 KFY05157.1 - 0.059 12.8 0.0 0.12 11.8 0.0 1.5 1 0 0 1 1 1 0 Putative methyltransferase Methyltransf_16 PF10294.9 KFY05157.1 - 0.064 13.0 0.0 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 Lysine methyltransferase PrmA PF06325.13 KFY05157.1 - 0.16 11.3 0.0 0.34 10.3 0.0 1.4 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Ank_2 PF12796.7 KFY05158.1 - 2.1e-23 82.7 3.4 6.5e-09 36.3 0.2 4.0 2 1 1 4 4 4 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KFY05158.1 - 1.3e-20 73.5 7.2 0.00028 21.4 0.0 7.4 3 2 5 8 8 8 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFY05158.1 - 1.1e-17 62.2 2.6 0.00067 19.9 0.0 7.6 9 0 0 9 9 9 4 Ankyrin repeat Ank_5 PF13857.6 KFY05158.1 - 2.6e-14 53.1 4.0 6.7e-05 23.1 0.1 5.0 3 2 2 5 5 5 4 Ankyrin repeats (many copies) Ank PF00023.30 KFY05158.1 - 1.1e-12 47.8 5.6 0.0026 18.1 0.0 7.0 7 0 0 7 7 7 3 Ankyrin repeat DUF5608 PF18356.1 KFY05158.1 - 0.029 14.4 0.1 2 8.5 0.0 3.0 2 1 1 3 3 3 0 Domain of unknown function (DUF5608) CFEM PF05730.11 KFY05161.1 - 1.4e-08 34.7 10.0 2.5e-08 33.9 10.0 1.4 1 0 0 1 1 1 1 CFEM domain FtsK_SpoIIIE PF01580.18 KFY05163.1 - 0.016 14.6 0.0 0.026 13.9 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family SET PF00856.28 KFY05165.1 - 2.7e-17 63.7 0.0 1.3e-16 61.5 0.0 2.1 1 1 0 1 1 1 1 SET domain Ribonucleas_3_3 PF14622.6 KFY05166.1 - 5.6e-11 42.7 0.0 7.5e-11 42.3 0.0 1.1 1 0 0 1 1 1 1 Ribonuclease-III-like Ribonuclease_3 PF00636.26 KFY05166.1 - 3e-10 40.6 0.0 4e-09 37.0 0.0 2.2 1 1 0 1 1 1 1 Ribonuclease III domain Peptidase_C65 PF10275.9 KFY05169.1 - 9.7e-67 225.0 0.0 1.3e-66 224.6 0.0 1.1 1 0 0 1 1 1 1 Peptidase C65 Otubain TauD PF02668.16 KFY05172.1 - 6.9e-14 52.3 0.0 9.1e-14 51.9 0.0 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Adeno_terminal PF02459.15 KFY05172.1 - 0.32 9.4 0.0 0.42 9.0 0.0 1.1 1 0 0 1 1 1 0 Adenoviral DNA terminal protein AAA_33 PF13671.6 KFY05173.1 - 9.6e-05 22.6 0.0 0.00018 21.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain SKI PF01202.22 KFY05173.1 - 0.00063 19.9 0.0 0.008 16.3 0.0 2.2 2 0 0 2 2 2 1 Shikimate kinase AAA_18 PF13238.6 KFY05173.1 - 0.0071 16.9 0.0 0.015 15.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 KFY05173.1 - 0.0084 15.4 0.0 0.015 14.6 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin AAA_22 PF13401.6 KFY05173.1 - 0.048 13.9 0.0 0.092 13.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 KFY05173.1 - 0.1 13.1 0.0 0.25 11.8 0.0 1.6 1 0 0 1 1 1 0 ABC transporter Aminotran_1_2 PF00155.21 KFY05174.1 - 8.3e-88 295.0 0.0 9.5e-88 294.8 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II CPT PF07931.12 KFY05175.1 - 3.3e-05 23.8 0.0 6.1e-05 22.9 0.0 1.6 1 0 0 1 1 1 1 Chloramphenicol phosphotransferase-like protein AAA_18 PF13238.6 KFY05175.1 - 0.0031 18.0 0.0 0.017 15.6 0.0 2.1 1 1 0 1 1 1 1 AAA domain PRK PF00485.18 KFY05175.1 - 0.028 14.2 0.0 0.053 13.3 0.0 1.4 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family AAA_16 PF13191.6 KFY05175.1 - 0.034 14.5 0.0 0.051 14.0 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain AAA_28 PF13521.6 KFY05175.1 - 0.036 14.3 0.0 0.063 13.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain CoaE PF01121.20 KFY05175.1 - 0.1 12.2 0.0 0.18 11.5 0.0 1.4 1 0 0 1 1 1 0 Dephospho-CoA kinase G-alpha PF00503.20 KFY05175.1 - 0.14 11.3 0.0 0.2 10.8 0.0 1.1 1 0 0 1 1 1 0 G-protein alpha subunit Zeta_toxin PF06414.12 KFY05175.1 - 0.18 11.1 0.0 0.29 10.4 0.0 1.2 1 0 0 1 1 1 0 Zeta toxin Cu_amine_oxid PF01179.20 KFY05178.1 - 2.1e-130 435.3 0.0 2.1e-97 326.6 0.1 2.1 1 1 1 2 2 2 2 Copper amine oxidase, enzyme domain Cu_amine_oxidN3 PF02728.16 KFY05178.1 - 4.5e-19 68.7 0.0 1.2e-18 67.3 0.0 1.7 1 0 0 1 1 1 1 Copper amine oxidase, N3 domain Cu_amine_oxidN2 PF02727.16 KFY05178.1 - 3.5e-15 56.0 0.1 7e-15 55.0 0.1 1.5 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain PD40 PF07676.12 KFY05180.1 - 6.3e-05 22.8 0.3 0.014 15.3 0.1 2.6 2 0 0 2 2 2 2 WD40-like Beta Propeller Repeat ANAPC4_WD40 PF12894.7 KFY05180.1 - 0.028 14.7 0.0 1.6 9.1 0.0 3.0 3 1 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain Cyclin_N PF00134.23 KFY05181.1 - 2.4e-10 40.3 0.0 3.6e-10 39.7 0.0 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.11 KFY05181.1 - 8.2e-05 23.0 0.1 0.00013 22.3 0.1 1.5 1 1 0 1 1 1 1 Cyclin Dak1_2 PF13684.6 KFY05182.1 - 0.15 11.1 0.6 0.19 10.8 0.6 1.1 1 0 0 1 1 1 0 Dihydroxyacetone kinase family Exonuc_VII_L PF02601.15 KFY05184.1 - 0.014 15.0 2.0 0.015 14.9 2.0 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit FH2 PF02181.23 KFY05184.1 - 0.031 13.4 1.1 0.039 13.1 1.1 1.3 1 0 0 1 1 1 0 Formin Homology 2 Domain Spc7 PF08317.11 KFY05184.1 - 0.045 12.6 5.0 0.055 12.4 5.0 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein Pox_A_type_inc PF04508.12 KFY05184.1 - 0.086 12.7 0.4 0.086 12.7 0.4 3.2 3 0 0 3 3 3 0 Viral A-type inclusion protein repeat DUF3552 PF12072.8 KFY05184.1 - 0.16 11.4 5.9 0.2 11.1 5.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) HSBP1 PF06825.12 KFY05184.1 - 0.19 11.6 2.8 0.4 10.6 0.9 2.5 2 1 0 2 2 2 0 Heat shock factor binding protein 1 DDE_1 PF03184.19 KFY05186.1 - 0.00099 18.8 0.0 0.0017 18.0 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease Ank_2 PF12796.7 KFY05187.1 - 2.9e-42 143.1 0.0 7.1e-14 52.2 0.0 4.3 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KFY05187.1 - 8.5e-32 105.6 0.1 0.00083 19.6 0.0 8.4 8 0 0 8 8 7 5 Ankyrin repeat Ank_4 PF13637.6 KFY05187.1 - 1.1e-27 96.0 2.6 4.3e-06 27.2 0.0 6.5 1 1 5 6 6 6 6 Ankyrin repeats (many copies) Ank PF00023.30 KFY05187.1 - 6.3e-24 83.3 7.2 0.0079 16.6 0.0 7.9 7 0 0 7 7 7 6 Ankyrin repeat Ank_5 PF13857.6 KFY05187.1 - 2.8e-22 78.5 5.2 3.3e-06 27.3 0.1 4.6 2 1 4 6 6 5 5 Ankyrin repeats (many copies) NACHT PF05729.12 KFY05187.1 - 7.2e-07 29.3 0.1 1.7e-06 28.0 0.1 1.6 1 0 0 1 1 1 1 NACHT domain DUF676 PF05057.14 KFY05187.1 - 4.4e-05 23.1 0.0 8.2e-05 22.2 0.0 1.4 1 0 0 1 1 1 1 Putative serine esterase (DUF676) NIL PF09383.10 KFY05187.1 - 7.7e-05 22.5 1.4 61 3.6 0.0 6.4 7 0 0 7 7 7 0 NIL domain AAA_16 PF13191.6 KFY05187.1 - 9.8e-05 22.8 0.1 0.00034 21.0 0.0 1.9 2 0 0 2 2 2 1 AAA ATPase domain Abhydrolase_6 PF12697.7 KFY05187.1 - 0.0037 17.9 0.0 0.016 15.9 0.0 2.0 2 0 0 2 2 2 1 Alpha/beta hydrolase family BRCA-2_helical PF09169.10 KFY05187.1 - 0.017 14.8 1.4 14 5.2 0.0 4.0 1 1 5 6 6 6 0 BRCA2, helical PGAP1 PF07819.13 KFY05187.1 - 0.04 13.6 0.0 0.088 12.5 0.0 1.5 1 1 0 1 1 1 0 PGAP1-like protein AAA_22 PF13401.6 KFY05187.1 - 0.047 14.0 0.1 0.2 12.0 0.0 2.0 2 0 0 2 2 2 0 AAA domain Nitro_FeMo-Co PF02579.17 KFY05187.1 - 0.064 13.6 1.2 85 3.6 0.0 4.3 2 1 2 4 4 4 0 Dinitrogenase iron-molybdenum cofactor RNA_helicase PF00910.22 KFY05187.1 - 0.15 12.5 0.0 0.34 11.3 0.0 1.6 1 0 0 1 1 1 0 RNA helicase RabGAP-TBC PF00566.18 KFY05188.1 - 5.2e-46 157.0 0.0 8.5e-46 156.3 0.0 1.4 1 0 0 1 1 1 1 Rab-GTPase-TBC domain GRAM PF02893.20 KFY05188.1 - 1.9e-05 24.5 0.0 5e-05 23.1 0.0 1.7 1 0 0 1 1 1 1 GRAM domain EF-hand_6 PF13405.6 KFY05188.1 - 8.7e-05 22.1 0.4 0.015 15.2 0.2 3.4 2 0 0 2 2 2 1 EF-hand domain EF-hand_1 PF00036.32 KFY05188.1 - 0.0043 16.5 1.5 0.096 12.3 0.8 3.3 3 0 0 3 3 3 1 EF hand EF-hand_5 PF13202.6 KFY05188.1 - 0.015 14.7 1.0 0.16 11.5 0.3 2.9 3 0 0 3 3 3 0 EF hand EF-hand_7 PF13499.6 KFY05188.1 - 0.021 15.3 2.3 0.11 12.9 0.3 3.3 3 1 1 4 4 4 0 EF-hand domain pair NFACT-C PF11923.8 KFY05189.1 - 4.7e-39 132.6 0.8 4.7e-39 132.6 0.8 2.8 2 0 0 2 2 2 1 NFACT protein C-terminal domain NFACT-R_1 PF05670.13 KFY05189.1 - 6.6e-31 107.2 0.0 1.8e-30 105.8 0.0 1.8 1 0 0 1 1 1 1 NFACT protein RNA binding domain FbpA PF05833.11 KFY05189.1 - 1.8e-30 106.1 3.5 1.8e-30 106.1 3.5 3.5 3 0 0 3 3 3 1 Fibronectin-binding protein A N-terminus (FbpA) zf-C3H1 PF10650.9 KFY05189.1 - 4.6e-13 48.6 2.0 7.4e-13 48.0 2.0 1.4 1 0 0 1 1 1 1 Putative zinc-finger domain DUF1366 PF07104.11 KFY05189.1 - 0.78 9.5 4.7 4.5 7.0 4.7 2.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1366) Myosin_head PF00063.21 KFY05190.1 - 1.3e-270 899.4 0.0 1.3e-270 899.4 0.0 1.9 2 0 0 2 2 2 1 Myosin head (motor domain) Myosin_N PF02736.19 KFY05190.1 - 6.8e-12 45.0 0.1 2e-11 43.6 0.1 1.8 1 0 0 1 1 1 1 Myosin N-terminal SH3-like domain Myosin_tail_1 PF01576.19 KFY05190.1 - 5.1e-11 41.2 104.7 5.1e-11 41.2 104.7 6.6 2 2 2 4 4 4 2 Myosin tail AAA_22 PF13401.6 KFY05190.1 - 0.035 14.4 0.0 0.035 14.4 0.0 5.6 6 0 0 6 6 6 0 AAA domain DUF2935 PF11155.8 KFY05190.1 - 8.6 6.7 17.8 10 6.5 3.5 6.3 4 3 1 5 5 5 0 Domain of unknown function (DUF2935) CTP_synth_N PF06418.14 KFY05191.1 - 6.3e-115 383.0 0.1 9.2e-115 382.5 0.1 1.2 1 0 0 1 1 1 1 CTP synthase N-terminus GATase PF00117.28 KFY05191.1 - 2.8e-54 183.8 0.0 4.3e-54 183.2 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 KFY05191.1 - 9e-06 25.6 0.3 0.0001 22.1 0.3 2.4 1 1 0 1 1 1 1 Peptidase C26 CbiA PF01656.23 KFY05191.1 - 0.0087 16.1 0.0 0.029 14.4 0.0 1.8 1 1 0 2 2 2 1 CobQ/CobB/MinD/ParA nucleotide binding domain DJ-1_PfpI PF01965.24 KFY05191.1 - 0.14 12.0 0.0 0.31 10.8 0.0 1.6 1 0 0 1 1 1 0 DJ-1/PfpI family F-box PF00646.33 KFY05192.1 - 0.00029 20.6 0.6 0.0015 18.3 0.1 2.3 2 0 0 2 2 2 1 F-box domain F-box_4 PF15966.5 KFY05192.1 - 0.12 12.3 0.0 0.33 10.8 0.0 1.8 1 0 0 1 1 1 0 F-box TauD PF02668.16 KFY05195.1 - 1.4e-35 123.4 0.5 1.6e-35 123.2 0.5 1.0 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family AAA_22 PF13401.6 KFY05197.1 - 2.9e-05 24.4 0.0 0.28 11.4 0.0 2.8 3 0 0 3 3 3 2 AAA domain FtsK_SpoIIIE PF01580.18 KFY05197.1 - 0.00094 18.6 0.0 0.0016 17.8 0.0 1.3 1 0 0 1 1 1 1 FtsK/SpoIIIE family Zot PF05707.12 KFY05197.1 - 0.025 14.2 0.0 0.072 12.7 0.0 1.7 2 0 0 2 2 2 0 Zonular occludens toxin (Zot) AAA_16 PF13191.6 KFY05197.1 - 0.044 14.2 0.0 2.7 8.3 0.0 2.8 3 0 0 3 3 3 0 AAA ATPase domain DUF87 PF01935.17 KFY05197.1 - 0.051 13.7 0.0 3.2 7.8 0.0 2.4 2 0 0 2 2 2 0 Helicase HerA, central domain Zeta_toxin PF06414.12 KFY05197.1 - 0.072 12.4 0.0 0.16 11.2 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin DUF3437 PF11919.8 KFY05197.1 - 0.15 12.0 0.0 0.4 10.6 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3437) SUZ PF12752.7 KFY05197.1 - 4.2 8.2 4.7 10 6.9 4.7 1.7 1 0 0 1 1 1 0 SUZ domain MFS_1 PF07690.16 KFY05198.1 - 3.7e-18 65.6 65.3 1e-15 57.6 36.4 2.9 2 1 1 3 3 3 3 Major Facilitator Superfamily Sugar_tr PF00083.24 KFY05200.1 - 1.3e-82 278.0 18.4 2.9e-82 276.9 18.4 1.5 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KFY05200.1 - 1.4e-29 103.2 10.7 2.4e-29 102.4 10.7 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_2 PF13347.6 KFY05200.1 - 4e-07 28.9 10.7 6.2e-05 21.7 2.4 2.4 2 0 0 2 2 2 2 MFS/sugar transport protein OATP PF03137.20 KFY05200.1 - 0.0054 15.1 0.6 0.0054 15.1 0.6 2.9 2 1 1 3 3 3 2 Organic Anion Transporter Polypeptide (OATP) family PTR2 PF00854.21 KFY05200.1 - 0.024 13.5 6.6 0.063 12.1 1.2 2.3 2 0 0 2 2 2 0 POT family Fungal_trans_2 PF11951.8 KFY05201.1 - 0.00018 20.5 0.2 0.00041 19.3 0.2 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain TMEM107 PF14995.6 KFY05201.1 - 1.4 9.4 3.7 7 7.1 0.5 2.3 2 0 0 2 2 2 0 Transmembrane protein Oxidored_FMN PF00724.20 KFY05202.1 - 1.8e-74 251.0 0.0 2.2e-74 250.8 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family AP_endonuc_2 PF01261.24 KFY05202.1 - 0.011 15.2 0.0 0.46 9.9 0.0 2.3 1 1 1 2 2 2 0 Xylose isomerase-like TIM barrel Mig-14 PF07395.11 KFY05202.1 - 0.17 11.2 0.0 0.25 10.7 0.0 1.2 1 0 0 1 1 1 0 Mig-14 PAN_3 PF08277.12 KFY05203.1 - 0.32 10.8 0.0 0.32 10.8 0.0 5.0 5 0 0 5 5 5 0 PAN-like domain MFS_1 PF07690.16 KFY05204.1 - 2.3e-31 109.0 66.8 6.4e-29 101.0 53.1 2.7 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KFY05204.1 - 1.2e-11 44.2 11.0 1.2e-11 44.2 11.0 2.9 3 0 0 3 3 3 1 Sugar (and other) transporter Anp1 PF03452.14 KFY05206.1 - 2.2e-104 348.6 0.0 2.7e-104 348.3 0.0 1.1 1 0 0 1 1 1 1 Anp1 HhH-GPD PF00730.25 KFY05207.1 - 2.3e-14 53.7 0.0 4.9e-14 52.7 0.0 1.5 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein CYYR1 PF10873.8 KFY05207.1 - 0.018 15.5 3.3 0.31 11.5 4.8 2.0 2 0 0 2 2 2 0 Cysteine and tyrosine-rich protein 1 TFIIF_alpha PF05793.12 KFY05207.1 - 6.9 5.1 5.7 9.7 4.6 5.7 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) tRNA-synt_1 PF00133.22 KFY05209.1 - 3.5e-55 187.4 0.0 1.2e-21 76.7 0.1 6.1 2 1 3 5 5 5 5 tRNA synthetases class I (I, L, M and V) tRNA-synt_1_2 PF13603.6 KFY05209.1 - 3.8e-42 143.9 0.0 6.2e-42 143.2 0.0 1.4 1 0 0 1 1 1 1 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1g PF09334.11 KFY05209.1 - 2.1e-27 95.9 0.0 1.5e-18 66.7 0.0 4.4 3 1 1 4 4 4 3 tRNA synthetases class I (M) Anticodon_1 PF08264.13 KFY05209.1 - 3.5e-08 33.6 0.1 5.9e-08 32.8 0.1 1.4 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.19 KFY05209.1 - 0.0043 16.4 0.0 0.22 10.8 0.0 2.7 3 0 0 3 3 3 1 tRNA synthetases class I (C) catalytic domain Zn-ribbon_8 PF09723.10 KFY05209.1 - 0.36 11.0 0.9 1.1 9.4 0.1 2.2 2 0 0 2 2 2 0 Zinc ribbon domain zf-ribbon_3 PF13248.6 KFY05209.1 - 0.98 8.9 2.9 7.5 6.1 0.2 2.4 2 0 0 2 2 2 0 zinc-ribbon domain AA_permease_2 PF13520.6 KFY05210.1 - 5.9e-62 209.9 35.1 8e-62 209.4 35.1 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 KFY05210.1 - 2.1e-26 92.6 26.2 2.1e-26 92.6 26.2 2.0 2 0 0 2 2 2 2 Amino acid permease YfzA PF14118.6 KFY05212.1 - 0.02 15.3 4.8 0.43 11.0 0.6 2.9 3 0 0 3 3 3 0 YfzA-like protein Acyl-CoA_dh_C PF12806.7 KFY05212.1 - 0.9 9.7 3.8 11 6.2 0.3 2.3 1 1 1 2 2 2 0 Acetyl-CoA dehydrogenase C-terminal like Peptidase_M48_N PF16491.5 KFY05212.1 - 1.3 8.9 12.2 0.021 14.7 2.0 2.5 2 1 0 2 2 2 0 CAAX prenyl protease N-terminal, five membrane helices Glyco_hydro_43 PF04616.14 KFY05213.1 - 2.7e-18 66.3 2.0 4.2e-18 65.7 2.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 Glyco_hydro_61 PF03443.14 KFY05214.1 - 1.7e-49 168.6 0.0 2.5e-49 168.0 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 CBM_1 PF00734.18 KFY05214.1 - 7.1e-13 48.3 13.2 2.2e-12 46.7 13.2 2.0 1 0 0 1 1 1 1 Fungal cellulose binding domain Toxin_7 PF05980.12 KFY05214.1 - 0.36 11.1 3.1 0.71 10.2 3.1 1.5 1 0 0 1 1 1 0 Toxin 7 Glyco_hydro_61 PF03443.14 KFY05215.1 - 1.1e-61 208.4 0.1 1.7e-61 207.8 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 CBM_1 PF00734.18 KFY05215.1 - 1.7e-12 47.0 13.5 4.6e-12 45.7 13.5 1.8 1 0 0 1 1 1 1 Fungal cellulose binding domain HTH_Tnp_ISL3 PF13542.6 KFY05215.1 - 0.087 12.3 0.2 0.19 11.1 0.2 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 Amino_oxidase PF01593.24 KFY05216.1 - 3.7e-43 148.5 0.0 1.2e-42 146.8 0.0 1.7 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 KFY05216.1 - 9.1e-12 45.0 0.0 3e-11 43.4 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 KFY05216.1 - 4.2e-06 26.2 0.0 8.4e-05 22.0 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KFY05216.1 - 0.00027 19.8 0.1 0.00044 19.1 0.1 1.3 1 0 0 1 1 1 1 HI0933-like protein FAD_binding_3 PF01494.19 KFY05216.1 - 0.0013 18.0 0.3 0.0021 17.4 0.3 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 KFY05216.1 - 0.0046 16.2 0.0 0.0086 15.3 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 KFY05216.1 - 0.032 14.8 0.1 0.077 13.6 0.1 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 KFY05216.1 - 0.051 12.6 0.0 0.076 12.1 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain NAD_binding_9 PF13454.6 KFY05216.1 - 0.1 12.6 0.0 0.47 10.4 0.0 2.0 2 0 0 2 2 2 0 FAD-NAD(P)-binding GIDA PF01134.22 KFY05216.1 - 0.12 11.4 0.0 0.19 10.8 0.0 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A GMC_oxred_C PF05199.13 KFY05217.1 - 7.9e-31 107.5 0.0 1.5e-30 106.6 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_N PF00732.19 KFY05217.1 - 3.2e-30 105.5 0.0 8.9e-25 87.7 0.0 2.8 1 1 1 2 2 2 2 GMC oxidoreductase NAD_binding_8 PF13450.6 KFY05217.1 - 7.6e-05 22.9 1.7 0.0002 21.5 1.0 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 KFY05217.1 - 0.0016 17.6 0.0 0.0023 17.1 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 KFY05217.1 - 0.0063 15.8 0.0 0.012 14.8 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 KFY05217.1 - 0.036 13.1 0.0 0.052 12.6 0.0 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein ApbA PF02558.16 KFY05217.1 - 0.043 13.5 0.4 0.082 12.6 0.4 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Pyr_redox_3 PF13738.6 KFY05217.1 - 0.094 12.0 0.1 8.4 5.5 0.0 2.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 KFY05217.1 - 0.1 11.2 0.3 0.15 10.8 0.3 1.2 1 0 0 1 1 1 0 HI0933-like protein DAO PF01266.24 KFY05217.1 - 0.5 9.9 3.6 2.1 7.8 2.2 2.3 2 1 0 2 2 2 0 FAD dependent oxidoreductase GAS2 PF02187.17 KFY05220.1 - 7.8e-07 29.1 0.0 1.6e-06 28.1 0.0 1.4 1 0 0 1 1 1 1 Growth-Arrest-Specific Protein 2 Domain CFEM PF05730.11 KFY05222.1 - 1e-32 112.0 36.1 1.4e-11 44.3 8.6 3.5 3 0 0 3 3 3 3 CFEM domain RepA1_leader PF08048.12 KFY05222.1 - 0.98 9.7 6.5 76 3.7 0.3 3.7 3 0 0 3 3 3 0 Tap RepA1 leader peptide Sugar_tr PF00083.24 KFY05223.1 - 1.6e-108 363.5 24.0 1.9e-108 363.2 24.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 KFY05223.1 - 2.5e-19 69.4 41.3 7.7e-13 48.1 9.5 2.1 1 1 0 2 2 2 2 Major Facilitator Superfamily Acyl-CoA_dh_1 PF00441.24 KFY05224.1 - 6.8e-23 81.5 0.4 1.2e-22 80.7 0.4 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Methyltransf_2 PF00891.18 KFY05224.1 - 3.2e-21 75.6 0.0 1.2e-20 73.8 0.0 1.9 2 0 0 2 2 2 1 O-methyltransferase domain Acyl-CoA_dh_N PF02771.16 KFY05224.1 - 1.9e-11 44.6 0.0 1.1e-10 42.1 0.0 2.2 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 KFY05224.1 - 1.4e-06 28.4 0.0 3.8e-06 27.0 0.0 1.8 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 KFY05224.1 - 1.6e-05 25.2 1.9 3.4e-05 24.1 1.9 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Dimerisation2 PF16864.5 KFY05224.1 - 0.0002 21.2 0.1 0.00049 20.0 0.1 1.6 1 0 0 1 1 1 1 Dimerisation domain Ad_Cy_reg PF16701.5 KFY05224.1 - 0.016 14.9 0.0 0.032 14.0 0.0 1.4 1 0 0 1 1 1 0 Adenylate cyclase regulatory domain Oxidored_molyb PF00174.19 KFY05226.1 - 2.2e-57 193.4 0.0 3.7e-57 192.7 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain p450 PF00067.22 KFY05226.1 - 2.7e-55 188.0 0.0 4.2e-55 187.3 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 Mo-co_dimer PF03404.16 KFY05226.1 - 6.6e-36 123.3 0.4 1.5e-35 122.2 0.4 1.6 1 0 0 1 1 1 1 Mo-co oxidoreductase dimerisation domain NAD_binding_1 PF00175.21 KFY05226.1 - 4.9e-27 94.7 0.0 2.1e-26 92.7 0.0 2.1 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 KFY05226.1 - 9.3e-24 83.7 0.0 1.9e-23 82.7 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain Cyt-b5 PF00173.28 KFY05226.1 - 2.4e-14 53.2 0.9 6e-14 51.9 0.1 2.0 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain NAD_binding_6 PF08030.12 KFY05226.1 - 0.055 13.6 0.0 2.2 8.4 0.0 2.7 1 1 0 2 2 2 0 Ferric reductase NAD binding domain Alpha-L-AF_C PF06964.12 KFY05227.1 - 8e-24 84.6 0.0 1.3e-23 84.0 0.0 1.3 1 0 0 1 1 1 1 Alpha-L-arabinofuranosidase C-terminal domain Glyco_hydr_30_2 PF14587.6 KFY05228.1 - 1.9e-16 60.7 6.8 4.4e-16 59.4 6.8 1.5 1 1 0 1 1 1 1 O-Glycosyl hydrolase family 30 NmrA PF05368.13 KFY05229.1 - 2.1e-35 122.3 0.0 5e-35 121.2 0.0 1.6 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 KFY05229.1 - 7.9e-13 48.7 0.0 1.1e-12 48.3 0.0 1.1 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 KFY05229.1 - 6.2e-05 22.6 0.0 0.00046 19.7 0.0 2.2 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 KFY05229.1 - 0.026 13.5 0.0 0.04 12.9 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family MFS_1 PF07690.16 KFY05230.1 - 3.2e-35 121.7 50.6 5.8e-35 120.9 50.6 1.5 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 KFY05230.1 - 4.3e-10 39.0 9.3 4.3e-10 39.0 9.3 2.2 2 0 0 2 2 2 1 Sugar (and other) transporter OATP PF03137.20 KFY05230.1 - 2.1 6.6 11.2 1.5 7.0 3.4 2.2 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family But2 PF09792.9 KFY05231.1 - 1.8e-33 115.9 1.0 3.3e-33 115.1 0.1 1.8 2 0 0 2 2 2 1 Ubiquitin 3 binding protein But2 C-terminal domain Ank_2 PF12796.7 KFY05234.1 - 1.2e-26 93.1 0.0 1.2e-11 45.0 0.0 3.2 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KFY05234.1 - 1.9e-18 66.5 0.0 5.4e-08 33.2 0.0 3.1 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFY05234.1 - 1.6e-16 58.7 0.0 0.026 15.0 0.0 5.1 4 0 0 4 4 4 4 Ankyrin repeat Ank PF00023.30 KFY05234.1 - 1.7e-12 47.2 0.0 0.17 12.4 0.0 5.3 5 0 0 5 5 5 3 Ankyrin repeat Ank_5 PF13857.6 KFY05234.1 - 3.9e-09 36.6 0.1 0.0042 17.4 0.0 3.0 2 0 0 2 2 2 2 Ankyrin repeats (many copies) NACHT PF05729.12 KFY05234.1 - 1.1e-07 32.0 0.0 9e-07 29.0 0.0 2.5 3 0 0 3 3 3 1 NACHT domain AAA_22 PF13401.6 KFY05234.1 - 1.4e-07 31.8 0.1 5.2e-07 30.0 0.1 1.9 1 0 0 1 1 1 1 AAA domain ATPase PF06745.13 KFY05234.1 - 1.3e-05 24.7 0.0 3.2e-05 23.4 0.0 1.6 1 0 0 1 1 1 1 KaiC AAA_16 PF13191.6 KFY05234.1 - 0.00012 22.5 0.0 0.0004 20.8 0.0 1.9 1 0 0 1 1 1 1 AAA ATPase domain TniB PF05621.11 KFY05234.1 - 0.0017 17.8 0.1 0.02 14.3 0.1 2.2 1 1 0 1 1 1 1 Bacterial TniB protein VWA_3_C PF18571.1 KFY05234.1 - 0.014 15.3 8.9 1.7 8.6 0.1 4.2 4 0 0 4 4 3 0 von Willebrand factor type A C-terminal domain SfsA PF03749.13 KFY05234.1 - 0.043 13.7 0.0 41 4.1 0.0 3.4 3 0 0 3 3 3 0 Sugar fermentation stimulation protein RE domain FAM76 PF16046.5 KFY05235.1 - 9.5e-05 21.9 12.6 9.5e-05 21.9 12.6 2.3 1 1 1 2 2 2 1 FAM76 protein AAA_13 PF13166.6 KFY05235.1 - 3.6 6.1 26.8 5.7 5.5 26.8 1.2 1 0 0 1 1 1 0 AAA domain DUF4661 PF15576.6 KFY05235.1 - 8.4 6.2 8.9 18 5.1 8.9 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4661) PI3K_P85_iSH2 PF16454.5 KFY05236.1 - 0.1 12.2 3.3 0.23 11.0 3.3 1.5 1 0 0 1 1 1 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain DMPK_coil PF08826.10 KFY05236.1 - 4 7.6 9.3 5.8 7.1 1.9 2.9 1 1 2 3 3 3 0 DMPK coiled coil domain like TetR_C_32 PF09209.11 KFY05237.1 - 0.1 12.6 0.0 15 5.6 0.0 2.2 1 1 1 2 2 2 0 Tetracyclin repressor-like, C-terminal domain AAA PF00004.29 KFY05238.1 - 1e-17 64.8 0.0 2.5e-17 63.5 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 KFY05238.1 - 0.00013 22.4 0.0 0.00048 20.6 0.0 1.9 1 1 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.14 KFY05238.1 - 0.00013 22.0 0.1 0.00064 19.7 0.0 2.2 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 KFY05238.1 - 0.00016 22.0 0.4 0.0019 18.4 0.0 2.6 2 1 1 3 3 3 1 AAA domain Bac_DnaA PF00308.18 KFY05238.1 - 0.0018 18.2 0.1 0.075 12.9 0.0 2.4 1 1 1 2 2 2 1 Bacterial dnaA protein AAA_28 PF13521.6 KFY05238.1 - 0.0042 17.3 0.0 0.81 9.9 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_24 PF13479.6 KFY05238.1 - 0.0046 16.7 0.1 0.018 14.8 0.0 2.0 2 1 0 2 2 2 1 AAA domain AAA_18 PF13238.6 KFY05238.1 - 0.005 17.4 0.0 0.017 15.7 0.0 2.0 2 0 0 2 2 1 1 AAA domain RuvB_N PF05496.12 KFY05238.1 - 0.0096 15.7 0.0 0.018 14.8 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_7 PF12775.7 KFY05238.1 - 0.02 14.4 0.0 0.039 13.5 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region Mg_chelatase PF01078.21 KFY05238.1 - 0.042 13.2 0.1 0.092 12.1 0.1 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_33 PF13671.6 KFY05238.1 - 0.052 13.7 0.0 0.1 12.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 KFY05238.1 - 0.069 13.1 0.0 0.74 9.7 0.0 2.4 1 1 1 2 2 2 0 NACHT domain AAA_14 PF13173.6 KFY05238.1 - 0.096 12.7 0.0 0.27 11.3 0.0 1.8 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 KFY05238.1 - 0.1 13.0 0.0 0.27 11.7 0.0 1.7 1 0 0 1 1 1 0 RNA helicase Zot PF05707.12 KFY05238.1 - 0.11 12.1 0.1 1.3 8.6 0.0 2.5 1 1 1 2 2 2 0 Zonular occludens toxin (Zot) HET-s_218-289 PF11558.8 KFY05238.1 - 0.16 12.0 0.0 0.41 10.7 0.0 1.7 1 0 0 1 1 1 0 Het-s 218-289 AAA_17 PF13207.6 KFY05238.1 - 0.17 12.3 0.0 0.44 11.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 KFY05238.1 - 0.18 11.5 0.1 0.66 9.7 0.0 1.9 2 0 0 2 2 2 0 AAA domain Pkinase PF00069.25 KFY05241.1 - 6.7e-12 45.3 0.0 9.5e-12 44.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFY05241.1 - 1.3e-11 44.2 0.0 6.5e-11 42.0 0.0 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.23 KFY05241.1 - 2.4e-08 34.2 0.3 0.0052 16.7 0.3 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family Choline_kinase PF01633.20 KFY05241.1 - 3.1e-06 27.0 0.0 0.006 16.2 0.0 2.1 1 1 1 2 2 2 2 Choline/ethanolamine kinase CENP-O PF09496.10 KFY05243.1 - 1.8 8.5 5.1 25 4.8 2.6 2.4 2 0 0 2 2 2 0 Cenp-O kinetochore centromere component rhaM PF05336.13 KFY05245.1 - 8.9e-35 119.0 0.1 1.3e-34 118.5 0.1 1.2 1 0 0 1 1 1 1 L-rhamnose mutarotase Herpes_LMP1 PF05297.11 KFY05245.1 - 0.25 10.5 1.4 0.35 10.0 1.4 1.1 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) DUF4663 PF15668.5 KFY05245.1 - 0.68 9.0 3.9 0.89 8.6 3.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4663) Thioredoxin PF00085.20 KFY05246.1 - 7.6e-08 32.3 0.0 1e-07 31.9 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.6 KFY05246.1 - 0.024 15.0 0.0 0.44 10.9 0.0 2.2 1 1 1 2 2 2 0 Thioredoxin-like Sep15_SelM PF08806.11 KFY05246.1 - 0.16 12.2 0.0 0.23 11.6 0.0 1.3 1 0 0 1 1 1 0 Sep15/SelM redox domain Thioredoxin_2 PF13098.6 KFY05246.1 - 0.16 12.4 0.0 0.51 10.8 0.0 1.8 1 1 0 1 1 1 0 Thioredoxin-like domain MFS_1 PF07690.16 KFY05247.1 - 1.4e-37 129.5 27.5 5.9e-28 97.8 10.5 2.6 2 1 1 3 3 3 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KFY05247.1 - 2.6e-15 56.2 3.8 2.6e-15 56.2 3.8 3.0 2 1 0 2 2 2 1 Sugar (and other) transporter TM140 PF14985.6 KFY05247.1 - 0.035 13.6 0.2 0.092 12.3 0.2 1.6 1 0 0 1 1 1 0 TM140 protein family TRI12 PF06609.13 KFY05247.1 - 0.18 10.2 10.1 0.0093 14.4 4.7 1.5 2 0 0 2 2 2 0 Fungal trichothecene efflux pump (TRI12) UPF0016 PF01169.19 KFY05248.1 - 5.9e-42 141.9 23.9 4.3e-21 75.0 8.5 2.3 2 0 0 2 2 2 2 Uncharacterized protein family UPF0016 TerC PF03741.16 KFY05248.1 - 0.012 15.3 0.3 0.012 15.3 0.3 1.7 2 0 0 2 2 2 0 Integral membrane protein TerC family Ion_trans PF00520.31 KFY05248.1 - 0.055 12.7 0.1 0.092 12.0 0.1 1.3 1 0 0 1 1 1 0 Ion transport protein RRM_1 PF00076.22 KFY05253.1 - 5.9e-12 45.2 0.2 1.4e-05 24.8 0.1 3.0 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KFY05253.1 - 0.013 15.3 0.0 0.047 13.6 0.0 1.8 2 0 0 2 2 2 0 Occluded RNA-recognition motif RRM_7 PF16367.5 KFY05253.1 - 0.052 13.7 0.0 0.1 12.7 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif PXA PF02194.15 KFY05254.1 - 6.1e-49 166.5 1.2 3.2e-48 164.1 1.2 2.4 1 0 0 1 1 1 1 PXA domain Nexin_C PF08628.12 KFY05254.1 - 1.2e-28 99.9 0.1 4.3e-28 98.1 0.1 2.1 1 0 0 1 1 1 1 Sorting nexin C terminal PX PF00787.24 KFY05254.1 - 4e-20 71.9 0.5 1.2e-19 70.3 0.5 1.9 1 0 0 1 1 1 1 PX domain RGS PF00615.19 KFY05254.1 - 1.7e-10 41.2 0.0 5.2e-10 39.6 0.0 1.9 1 0 0 1 1 1 1 Regulator of G protein signaling domain CPDase PF07823.11 KFY05254.1 - 0.051 13.3 0.0 0.099 12.3 0.0 1.4 1 0 0 1 1 1 0 Cyclic phosphodiesterase-like protein DUF2964 PF11177.8 KFY05254.1 - 1.1 9.5 5.2 0.7 10.1 3.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2964) Methyltransf_4 PF02390.17 KFY05255.1 - 4.9e-56 188.9 0.0 6.2e-56 188.6 0.0 1.1 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_25 PF13649.6 KFY05255.1 - 2.6e-05 24.8 0.0 8.6e-05 23.2 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 KFY05255.1 - 0.00038 21.1 0.0 0.00075 20.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 KFY05255.1 - 0.0017 17.9 0.0 0.003 17.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_32 PF13679.6 KFY05255.1 - 0.0021 18.1 0.0 0.007 16.4 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 KFY05255.1 - 0.018 14.8 0.0 0.038 13.8 0.0 1.6 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_11 PF08241.12 KFY05255.1 - 0.023 15.4 0.0 0.097 13.3 0.0 2.2 2 1 0 2 2 2 0 Methyltransferase domain Homoserine_dh PF00742.19 KFY05257.1 - 9.2e-52 175.4 0.0 1.3e-51 175.0 0.0 1.2 1 0 0 1 1 1 1 Homoserine dehydrogenase NAD_binding_3 PF03447.16 KFY05257.1 - 8.1e-19 68.4 0.0 1.3e-18 67.7 0.0 1.3 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain Sacchrp_dh_NADP PF03435.18 KFY05257.1 - 0.064 13.5 1.1 0.2 11.9 1.1 1.8 1 1 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain DUF5326 PF17260.2 KFY05264.1 - 1.9 8.7 6.4 0.15 12.2 0.5 2.2 3 0 0 3 3 3 0 Family of unknown function (DUF5326) Bac_rhamnosid6H PF17389.2 KFY05265.1 - 8.2e-18 64.8 2.3 2.2e-16 60.1 0.6 2.3 2 0 0 2 2 2 1 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain Bac_rhamnosid_C PF17390.2 KFY05265.1 - 1.5e-14 53.5 1.3 3.7e-14 52.3 1.3 1.7 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase C-terminal domain F5_F8_type_C PF00754.25 KFY05265.1 - 1.5e-09 38.0 0.4 5.1e-09 36.3 0.2 2.1 2 0 0 2 2 2 1 F5/8 type C domain DUF608 PF04685.13 KFY05265.1 - 6.2e-07 28.9 0.8 1.3e-06 27.9 0.8 1.4 1 0 0 1 1 1 1 Glycosyl-hydrolase family 116, catalytic region GDE_C PF06202.14 KFY05265.1 - 7.3e-05 21.9 0.1 0.00012 21.2 0.1 1.2 1 0 0 1 1 1 1 Amylo-alpha-1,6-glucosidase Trehalase PF01204.18 KFY05265.1 - 0.00022 20.2 0.1 0.00033 19.6 0.1 1.1 1 0 0 1 1 1 1 Trehalase Glyco_hydro_36 PF17167.4 KFY05265.1 - 0.0053 15.5 0.0 0.0092 14.7 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase 36 superfamily, catalytic domain Bac_rhamnosid PF05592.11 KFY05265.1 - 0.018 15.0 0.0 0.049 13.6 0.0 1.7 1 1 0 1 1 1 0 Bacterial alpha-L-rhamnosidase concanavalin-like domain Glyco_hydro_63 PF03200.16 KFY05265.1 - 0.079 11.7 0.0 0.14 10.9 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 63 C-terminal domain Glyco_hydro_11 PF00457.17 KFY05266.1 - 3.8e-83 277.5 16.4 4.4e-83 277.3 16.4 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 11 W_rich_C PF07483.11 KFY05266.1 - 0.09 12.9 0.6 0.36 11.0 0.1 2.0 2 0 0 2 2 2 0 Tryptophan-rich Synechocystis species C-terminal domain Potass_KdpF PF09604.10 KFY05267.1 - 0.041 13.9 0.0 0.099 12.7 0.0 1.6 1 0 0 1 1 1 0 F subunit of K+-transporting ATPase (Potass_KdpF) Pectate_lyase_3 PF12708.7 KFY05268.1 - 1.2e-71 241.0 6.9 9e-68 228.3 1.2 4.2 4 2 1 5 5 5 2 Pectate lyase superfamily protein Peptidase_S8 PF00082.22 KFY05268.1 - 7.1e-14 51.8 0.9 2.9e-13 49.7 0.0 2.3 2 0 0 2 2 2 1 Subtilase family Baculo_LEF-10 PF07206.11 KFY05270.1 - 0.14 12.4 0.1 0.35 11.1 0.0 1.7 1 1 0 1 1 1 0 Baculovirus late expression factor 10 (LEF-10) 3-HAO PF06052.12 KFY05273.1 - 2.2e-09 37.1 0.1 2.2e-09 37.1 0.1 1.0 1 0 0 1 1 1 1 3-hydroxyanthranilic acid dioxygenase Ctr PF04145.15 KFY05274.1 - 7e-05 23.5 0.0 9.1e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 Ctr copper transporter family Sugar_tr PF00083.24 KFY05275.1 - 5e-63 213.5 20.1 4.2e-43 147.8 3.0 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 KFY05275.1 - 1.6e-05 24.1 48.6 5.3e-05 22.3 14.5 2.8 2 2 0 2 2 2 2 Major Facilitator Superfamily DUF4190 PF13828.6 KFY05275.1 - 1.2 8.9 9.4 0.5 10.2 4.7 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF4190) RraA-like PF03737.15 KFY05276.1 - 6.4e-34 117.3 0.3 7.9e-34 117.0 0.3 1.1 1 0 0 1 1 1 1 Aldolase/RraA 2-Hacid_dh_C PF02826.19 KFY05277.1 - 9.8e-56 187.9 0.0 1.3e-55 187.5 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 KFY05277.1 - 8.7e-27 93.4 0.1 1.1e-26 93.1 0.1 1.0 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 KFY05277.1 - 2.3e-05 24.6 0.1 4.4e-05 23.7 0.1 1.5 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.17 KFY05277.1 - 0.017 15.7 0.1 0.069 13.7 0.1 2.0 1 1 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent IlvN PF07991.12 KFY05277.1 - 0.031 13.9 0.1 0.085 12.4 0.0 1.8 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain Gp_dh_N PF00044.24 KFY05277.1 - 0.045 14.1 0.1 0.3 11.5 0.1 2.2 2 0 0 2 2 2 0 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain Sacchrp_dh_NADP PF03435.18 KFY05277.1 - 0.65 10.3 2.9 57 4.0 0.0 3.6 4 0 0 4 4 4 0 Saccharopine dehydrogenase NADP binding domain Ldh_2 PF02615.14 KFY05278.1 - 1.4e-115 386.0 0.3 1.6e-115 385.8 0.3 1.0 1 0 0 1 1 1 1 Malate/L-lactate dehydrogenase Gly_rich_SFCGS PF14272.6 KFY05278.1 - 0.045 13.8 0.3 0.098 12.7 0.3 1.5 1 0 0 1 1 1 0 Glycine-rich SFCGS MFS_1 PF07690.16 KFY05279.1 - 1.1e-26 93.6 24.4 1.5e-26 93.2 24.4 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Amidohydro_2 PF04909.14 KFY05280.1 - 8.5e-27 94.7 0.1 1.1e-26 94.3 0.1 1.1 1 0 0 1 1 1 1 Amidohydrolase UBA_3 PF09288.10 KFY05280.1 - 0.043 13.6 0.0 0.098 12.5 0.0 1.7 1 0 0 1 1 1 0 Fungal ubiquitin-associated domain Epimerase PF01370.21 KFY05280.1 - 0.21 11.0 0.0 0.33 10.4 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Fungal_trans PF04082.18 KFY05281.1 - 2e-22 79.5 0.1 3.4e-22 78.8 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KFY05281.1 - 2.6e-08 33.9 9.6 4.6e-08 33.0 9.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ELM2 PF01448.24 KFY05281.1 - 0.047 14.4 0.5 1.9 9.3 0.1 3.1 3 0 0 3 3 3 0 ELM2 domain adh_short PF00106.25 KFY05284.1 - 7.5e-15 54.9 0.0 1.8e-11 43.9 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 KFY05284.1 - 5.7e-08 32.6 0.0 6.8e-07 29.1 0.0 2.0 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 KFY05284.1 - 2.1e-06 27.8 0.0 2.8e-06 27.4 0.0 1.2 1 0 0 1 1 1 1 KR domain NACHT PF05729.12 KFY05284.1 - 0.022 14.7 0.0 0.036 14.0 0.0 1.4 1 1 0 1 1 1 0 NACHT domain Sulfotransfer_4 PF17784.1 KFY05284.1 - 0.08 12.8 0.0 0.16 11.8 0.0 1.4 1 0 0 1 1 1 0 Sulfotransferase domain zf-C2H2 PF00096.26 KFY05287.1 - 0.00087 19.6 23.1 0.11 13.0 0.6 6.1 6 0 0 6 6 6 3 Zinc finger, C2H2 type zf-C2H2_aberr PF17017.5 KFY05287.1 - 0.0093 16.1 0.5 0.5 10.5 0.0 3.5 4 0 0 4 4 4 1 Aberrant zinc-finger zf-met PF12874.7 KFY05287.1 - 0.015 15.7 3.6 0.13 12.7 0.4 3.9 4 0 0 4 4 4 0 Zinc-finger of C2H2 type lci PF12197.8 KFY05287.1 - 0.036 13.9 0.2 0.1 12.4 0.2 1.7 1 0 0 1 1 1 0 Bacillus cereus group antimicrobial protein zf-C2H2_jaz PF12171.8 KFY05287.1 - 1.2 9.5 10.9 1 9.7 0.3 4.5 4 1 0 4 4 4 0 Zinc-finger double-stranded RNA-binding zf-Di19 PF05605.12 KFY05287.1 - 2.9 8.3 7.0 15 5.9 0.4 3.6 3 0 0 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_4 PF13894.6 KFY05287.1 - 4 8.5 31.8 0.12 13.3 0.9 7.2 8 1 0 8 8 8 0 C2H2-type zinc finger GLE1 PF07817.13 KFY05290.1 - 3.5e-58 196.8 0.0 4.9e-58 196.3 0.0 1.2 1 0 0 1 1 1 1 GLE1-like protein Ndc1_Nup PF09531.10 KFY05290.1 - 0.31 9.7 7.9 0.42 9.2 7.9 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup CDC27 PF09507.10 KFY05290.1 - 9 5.6 10.8 15 4.8 10.8 1.4 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 RNB PF00773.19 KFY05291.1 - 5.8e-88 295.4 0.0 9.4e-88 294.7 0.0 1.4 1 0 0 1 1 1 1 RNB domain OB_Dis3 PF17849.1 KFY05291.1 - 8.8e-26 89.7 0.1 2.7e-25 88.2 0.0 1.9 2 0 0 2 2 2 1 Dis3-like cold-shock domain 2 (CSD2) Dis3l2_C_term PF17877.1 KFY05291.1 - 5.6e-25 87.5 0.0 1.6e-24 86.0 0.0 1.8 1 0 0 1 1 1 1 DIS3-like exonuclease 2 C terminal CSD2 PF17876.1 KFY05291.1 - 2.1e-06 27.8 0.0 0.011 15.9 0.0 2.8 2 0 0 2 2 2 2 Cold shock domain Rrp44_CSD1 PF17216.3 KFY05291.1 - 0.022 14.5 0.0 0.058 13.1 0.0 1.7 1 0 0 1 1 1 0 Rrp44-like cold shock domain Ferritin_2 PF13668.6 KFY05292.1 - 3.1e-40 137.5 3.2 4.3e-40 137.1 3.2 1.2 1 0 0 1 1 1 1 Ferritin-like domain NAD_binding_10 PF13460.6 KFY05294.1 - 0.00014 21.8 0.0 0.00014 21.8 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding NAD_binding_4 PF07993.12 KFY05294.1 - 0.0005 19.3 0.1 0.033 13.4 0.0 2.1 2 0 0 2 2 2 2 Male sterility protein Polysacc_synt_2 PF02719.15 KFY05294.1 - 0.0082 15.3 0.0 0.019 14.1 0.0 1.6 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein Epimerase PF01370.21 KFY05294.1 - 0.011 15.2 0.0 0.015 14.8 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Semialdhyde_dh PF01118.24 KFY05294.1 - 0.095 13.1 0.0 0.16 12.5 0.0 1.4 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain KR PF08659.10 KFY05294.1 - 0.19 11.6 0.0 0.28 11.1 0.0 1.3 1 0 0 1 1 1 0 KR domain adh_short_C2 PF13561.6 KFY05296.1 - 8.4e-44 149.9 1.6 1.1e-43 149.4 1.6 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 KFY05296.1 - 1.7e-41 141.8 1.5 2.3e-41 141.4 0.4 1.6 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.10 KFY05296.1 - 7.4e-12 45.5 0.8 1.2e-11 44.9 0.8 1.3 1 0 0 1 1 1 1 KR domain N2227 PF07942.12 KFY05297.1 - 1.7e-97 325.9 0.0 2.2e-97 325.5 0.0 1.1 1 0 0 1 1 1 1 N2227-like protein Methyltransf_23 PF13489.6 KFY05297.1 - 0.018 14.9 0.0 0.043 13.6 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain HEAT_EZ PF13513.6 KFY05298.1 - 1.5e-32 111.6 14.3 6.1e-17 61.7 0.0 10.5 9 2 2 11 11 11 5 HEAT-like repeat HEAT PF02985.22 KFY05298.1 - 6.4e-26 88.2 9.4 3.2e-06 26.9 0.0 9.8 10 0 0 10 10 10 4 HEAT repeat PAC4 PF16093.5 KFY05298.1 - 2.7e-19 69.1 0.2 1.4e-18 66.9 0.1 2.2 2 0 0 2 2 2 1 Proteasome assembly chaperone 4 HEAT_2 PF13646.6 KFY05298.1 - 3.4e-18 65.8 0.8 5.1e-06 26.8 0.0 7.6 5 3 2 7 7 7 4 HEAT repeats Cnd1 PF12717.7 KFY05298.1 - 5e-12 46.1 0.0 0.076 13.0 0.0 5.3 5 0 0 5 5 5 4 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.7 KFY05298.1 - 3.1e-07 30.9 0.0 0.95 10.1 0.0 5.9 5 2 2 7 7 7 3 Vacuolar 14 Fab1-binding region MMS19_C PF12460.8 KFY05298.1 - 9.6e-07 28.3 4.8 0.046 12.8 0.0 5.1 5 1 1 6 6 6 2 RNAPII transcription regulator C-terminal CLASP_N PF12348.8 KFY05298.1 - 1.3e-06 28.2 0.0 0.24 10.9 0.0 6.4 7 1 1 8 8 8 1 CLASP N terminal IBN_N PF03810.19 KFY05298.1 - 1.9e-06 27.7 4.5 7.5e-06 25.8 0.1 4.2 5 1 0 5 5 5 1 Importin-beta N-terminal domain Telomere_reg-2 PF10193.9 KFY05298.1 - 6.8e-05 23.3 0.3 0.0088 16.5 0.0 3.6 4 0 0 4 4 4 1 Telomere length regulation protein Arm PF00514.23 KFY05298.1 - 0.00011 22.0 3.1 0.63 10.2 0.0 5.6 6 0 0 6 6 6 1 Armadillo/beta-catenin-like repeat Adaptin_N PF01602.20 KFY05298.1 - 0.00027 19.6 0.0 1.8 7.0 0.1 3.9 2 2 1 3 3 3 1 Adaptin N terminal region RTP1_C1 PF10363.9 KFY05298.1 - 0.0021 18.2 0.1 0.087 13.0 0.0 3.1 3 0 0 3 3 3 1 Required for nuclear transport of RNA pol II C-terminus 1 TAF6_C PF07571.13 KFY05298.1 - 0.13 12.6 0.0 31 5.0 0.0 3.5 2 0 0 2 2 2 0 TAF6 C-terminal HEAT repeat domain RIX1 PF08167.12 KFY05298.1 - 0.21 11.3 1.0 17 5.1 0.0 3.9 4 0 0 4 4 4 0 rRNA processing/ribosome biogenesis HEAT_PBS PF03130.16 KFY05298.1 - 1.9 9.4 5.2 14 6.7 0.0 4.9 6 0 0 6 6 4 0 PBS lyase HEAT-like repeat RCC1 PF00415.18 KFY05299.1 - 5.2e-60 199.9 7.2 5.4e-09 36.5 0.2 7.6 7 1 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 KFY05299.1 - 3.1e-35 119.2 30.5 7.7e-09 35.1 0.0 6.7 7 0 0 7 7 7 6 Regulator of chromosome condensation (RCC1) repeat Caprin-1_C PF12287.8 KFY05299.1 - 1.2 9.2 6.1 1.9 8.6 6.1 1.2 1 0 0 1 1 1 0 Cytoplasmic activation/proliferation-associated protein-1 C term Pam16 PF03656.13 KFY05300.1 - 5.5e-37 126.6 0.5 7e-37 126.3 0.5 1.1 1 0 0 1 1 1 1 Pam16 DUF1682 PF07946.14 KFY05300.1 - 0.022 14.0 0.0 0.026 13.8 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) DUF5429 PF17494.2 KFY05300.1 - 0.025 14.6 0.1 0.041 13.9 0.1 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5429) TctA PF01970.16 KFY05301.1 - 0.4 9.3 0.7 0.59 8.8 0.7 1.1 1 0 0 1 1 1 0 Tripartite tricarboxylate transporter TctA family GAGA_bind PF06217.12 KFY05301.1 - 0.86 9.8 6.3 0.52 10.5 3.0 2.1 2 0 0 2 2 2 0 GAGA binding protein-like family zf-C3HC4_3 PF13920.6 KFY05301.1 - 1.8 8.5 6.6 5.1 7.1 2.7 2.3 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) O-antigen_lig PF13425.6 KFY05301.1 - 6.6 5.4 5.3 9.3 4.9 5.3 1.1 1 0 0 1 1 1 0 O-antigen ligase like membrane protein RRM_1 PF00076.22 KFY05302.1 - 9.5e-09 35.0 0.1 1.8e-08 34.1 0.1 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 KFY05302.1 - 4.2e-05 23.3 0.0 8.1e-05 22.4 0.0 1.5 1 0 0 1 1 1 1 Occluded RNA-recognition motif DUF3510 PF12022.8 KFY05302.1 - 0.0025 18.2 0.6 0.0073 16.7 0.6 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF3510) Nup35_RRM_2 PF14605.6 KFY05302.1 - 0.0026 17.7 0.0 0.0062 16.5 0.0 1.6 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif Allexi_40kDa PF05549.11 KFY05302.1 - 0.028 13.9 0.4 0.045 13.3 0.4 1.2 1 0 0 1 1 1 0 Allexivirus 40kDa protein RRM_3 PF08777.11 KFY05302.1 - 0.083 12.9 0.3 0.083 12.9 0.3 1.9 2 0 0 2 2 2 0 RNA binding motif Brix PF04427.18 KFY05306.1 - 5.7e-26 91.8 0.0 7.6e-26 91.4 0.0 1.2 1 0 0 1 1 1 1 Brix domain Glyco_hydro_2_C PF02836.17 KFY05307.1 - 7.8e-86 287.9 0.0 1.2e-85 287.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Glyco_hydro_2_N PF02837.18 KFY05307.1 - 1.2e-26 93.6 0.5 2.5e-26 92.6 0.5 1.6 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_2 PF00703.21 KFY05307.1 - 1.9e-10 41.4 0.2 4.3e-10 40.2 0.2 1.6 1 0 0 1 1 1 1 Glycosyl hydrolases family 2 FAD_binding_4 PF01565.23 KFY05310.1 - 2.9e-16 59.5 0.0 4.8e-16 58.8 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain zf-DNL PF05180.12 KFY05311.1 - 0.022 14.7 0.1 0.04 13.8 0.1 1.4 1 0 0 1 1 1 0 DNL zinc finger bZIP_2 PF07716.15 KFY05315.1 - 1.9e-05 24.6 19.6 1.9e-05 24.6 19.6 2.2 1 1 1 2 2 2 1 Basic region leucine zipper bZIP_1 PF00170.21 KFY05315.1 - 9.1e-05 22.5 18.1 0.00016 21.7 18.1 1.4 1 0 0 1 1 1 1 bZIP transcription factor bZIP_Maf PF03131.17 KFY05315.1 - 0.056 14.0 14.8 0.099 13.2 14.8 1.4 1 0 0 1 1 1 0 bZIP Maf transcription factor GrpE PF01025.19 KFY05315.1 - 0.42 10.3 0.1 0.42 10.3 0.1 2.6 2 1 0 2 2 2 0 GrpE Cytochrom_B558a PF05038.13 KFY05315.1 - 1 8.9 2.4 1.6 8.3 2.4 1.2 1 0 0 1 1 1 0 Cytochrome Cytochrome b558 alpha-subunit APG6_N PF17675.1 KFY05315.1 - 3 8.4 17.6 31 5.1 17.6 2.1 1 1 0 1 1 1 0 Apg6 coiled-coil region Ank_2 PF12796.7 KFY05320.1 - 6.4e-69 228.6 5.5 1.8e-16 60.5 0.0 7.8 2 2 5 7 7 7 7 Ankyrin repeats (3 copies) Ank_4 PF13637.6 KFY05320.1 - 1.9e-48 162.2 11.5 1.3e-07 32.0 0.2 9.6 6 3 5 11 11 11 9 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFY05320.1 - 1.2e-46 151.2 17.9 0.0011 19.3 0.0 13.4 13 0 0 13 13 13 10 Ankyrin repeat Ank PF00023.30 KFY05320.1 - 4.6e-39 131.2 30.3 0.0079 16.6 0.0 13.4 13 0 0 13 13 13 12 Ankyrin repeat Ank_5 PF13857.6 KFY05320.1 - 4.3e-38 128.9 35.0 2.5e-08 34.0 0.0 12.6 3 2 11 14 14 14 10 Ankyrin repeats (many copies) CHAP PF05257.16 KFY05320.1 - 0.078 13.6 1.8 21 5.7 0.1 4.1 3 1 1 4 4 4 0 CHAP domain DUF1854 PF08909.11 KFY05320.1 - 0.13 12.1 0.0 0.24 11.2 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1854) Ank_2 PF12796.7 KFY05321.1 - 6.6e-70 231.7 2.6 2.1e-15 57.0 0.0 6.3 1 1 5 7 7 7 7 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KFY05321.1 - 1.7e-55 178.4 4.4 1.6e-05 24.9 0.0 11.9 12 0 0 12 12 12 11 Ankyrin repeat Ank_4 PF13637.6 KFY05321.1 - 3.4e-51 171.0 3.6 9.2e-08 32.5 0.0 8.1 3 3 4 8 8 8 8 Ankyrin repeats (many copies) Ank PF00023.30 KFY05321.1 - 7.6e-46 152.6 12.5 6.5e-06 26.4 0.0 11.4 11 0 0 11 11 11 10 Ankyrin repeat Ank_5 PF13857.6 KFY05321.1 - 7.8e-42 140.8 15.4 1.4e-08 34.9 0.0 10.0 2 2 8 10 10 10 9 Ankyrin repeats (many copies) F-box-like PF12937.7 KFY05321.1 - 1.9e-06 27.6 0.5 9.3e-06 25.4 0.1 2.4 3 0 0 3 3 3 1 F-box-like VWA_3_C PF18571.1 KFY05321.1 - 0.017 15.0 0.1 11 6.0 0.0 3.8 3 0 0 3 3 3 0 von Willebrand factor type A C-terminal domain RVP PF00077.20 KFY05321.1 - 0.17 12.2 0.6 13 6.2 0.0 3.5 2 1 2 4 4 4 0 Retroviral aspartyl protease Lipase_GDSL_2 PF13472.6 KFY05324.1 - 1.7e-21 77.4 1.4 3.5e-21 76.4 1.4 1.6 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 KFY05324.1 - 2.2e-11 44.1 0.2 3.1e-11 43.6 0.2 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Glyco_hydro_43 PF04616.14 KFY05325.1 - 3.5e-45 154.6 7.0 4e-45 154.4 7.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 Laminin_G_1 PF00054.23 KFY05326.1 - 0.0015 18.8 0.0 0.0031 17.7 0.0 1.4 1 0 0 1 1 1 1 Laminin G domain Laminin_G_2 PF02210.24 KFY05326.1 - 0.0069 17.0 0.0 0.016 15.8 0.0 1.6 1 0 0 1 1 1 1 Laminin G domain MFS_1 PF07690.16 KFY05327.1 - 7.4e-36 123.8 29.8 2.9e-35 121.9 26.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 KFY05327.1 - 4.6e-05 22.9 0.6 4.6e-05 22.9 0.6 2.6 2 1 2 4 4 4 1 Uncharacterised MFS-type transporter YbfB Ac110_PIF PF07280.11 KFY05327.1 - 1.3 8.8 4.7 4.6 7.1 4.7 1.9 1 0 0 1 1 1 0 Per os infectivity factor AC110 DHDPS PF00701.22 KFY05328.1 - 8.5e-38 129.7 0.0 1.1e-37 129.4 0.0 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family STALD PF18185.1 KFY05328.1 - 0.033 13.5 0.0 6.5 6.0 0.0 2.2 2 0 0 2 2 2 0 Sir2- and TIR-associating SLOG family Fungal_trans_2 PF11951.8 KFY05329.1 - 8.6e-18 64.3 0.0 1.2e-17 63.8 0.0 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Aldo_ket_red PF00248.21 KFY05330.1 - 3.6e-65 220.1 0.0 4.3e-65 219.8 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family YCF90 PF17088.5 KFY05330.1 - 0.081 12.2 0.0 0.12 11.7 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein family Aminotran_4 PF01063.19 KFY05331.1 - 1.4e-41 142.8 0.0 1.6e-41 142.6 0.0 1.1 1 0 0 1 1 1 1 Amino-transferase class IV DUF2254 PF10011.9 KFY05331.1 - 0.28 9.9 0.0 0.4 9.4 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2254) DAO PF01266.24 KFY05332.1 - 8.2e-29 101.3 0.1 9.6e-29 101.1 0.1 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 KFY05332.1 - 0.00026 21.5 0.6 0.00098 19.6 0.7 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KFY05332.1 - 0.0004 19.7 0.1 0.00093 18.5 0.1 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KFY05332.1 - 0.019 15.1 0.2 0.054 13.7 0.2 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 KFY05332.1 - 0.11 11.7 0.5 0.67 9.2 0.1 2.0 2 0 0 2 2 2 0 Thi4 family NAD_binding_9 PF13454.6 KFY05332.1 - 0.12 12.3 0.1 0.22 11.5 0.1 1.5 1 1 0 1 1 1 0 FAD-NAD(P)-binding UDPG_MGDP_dh_N PF03721.14 KFY05332.1 - 0.23 11.0 0.5 0.38 10.3 0.5 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Fungal_trans_2 PF11951.8 KFY05333.1 - 4.6e-30 104.7 9.4 7.4e-30 104.0 9.4 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KFY05333.1 - 0.00011 22.2 3.4 0.00028 20.9 3.4 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Med3 PF11593.8 KFY05334.1 - 2 7.5 8.3 26 3.9 0.0 2.0 1 1 1 2 2 2 0 Mediator complex subunit 3 fungal F-box PF00646.33 KFY05335.1 - 0.0051 16.7 0.2 0.011 15.5 0.2 1.5 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 KFY05335.1 - 0.081 12.8 1.3 0.12 12.3 0.1 1.9 2 0 0 2 2 2 0 F-box-like tRNA-synt_1c PF00749.21 KFY05336.1 - 1.1e-100 336.6 0.1 1.5e-100 336.2 0.1 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.18 KFY05336.1 - 6.2e-37 127.1 0.3 1.2e-36 126.2 0.3 1.5 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain tRNA-synt_1e PF01406.19 KFY05336.1 - 0.025 13.9 0.4 0.072 12.4 0.4 1.6 1 1 0 1 1 1 0 tRNA synthetases class I (C) catalytic domain DSS1_SEM1 PF05160.13 KFY05336.1 - 0.91 9.6 6.6 0.72 10.0 2.9 2.6 2 0 0 2 2 2 0 DSS1/SEM1 family Zn_clus PF00172.18 KFY05337.1 - 1.1e-09 38.3 10.6 1.6e-09 37.7 10.6 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KFY05337.1 - 2.7e-05 23.3 0.0 6.2e-05 22.2 0.0 1.7 1 1 0 1 1 1 1 Fungal specific transcription factor domain Spt20 PF12090.8 KFY05337.1 - 1.8 8.2 8.0 3.3 7.3 8.0 1.4 1 0 0 1 1 1 0 Spt20 family Copper-fist PF00649.18 KFY05338.1 - 3.7e-19 67.9 1.9 3.7e-19 67.9 1.9 2.9 1 1 2 3 3 3 1 Copper fist DNA binding domain MFS_1 PF07690.16 KFY05339.1 - 7.5e-40 136.9 33.4 7.5e-40 136.9 33.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 KFY05339.1 - 4.4e-08 32.4 12.1 4.4e-08 32.4 12.1 2.7 3 1 0 3 3 3 1 Sugar (and other) transporter OATP PF03137.20 KFY05339.1 - 0.27 9.5 5.2 3.9 5.6 5.3 2.3 1 1 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family MFS_1 PF07690.16 KFY05341.1 - 2.2e-26 92.6 31.0 9e-25 87.3 27.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 KFY05341.1 - 0.018 13.5 4.6 0.0073 14.8 2.0 1.6 2 0 0 2 2 2 0 Fungal trichothecene efflux pump (TRI12) DUF3054 PF11255.8 KFY05341.1 - 3.1 8.3 11.8 0.78 10.3 2.3 3.4 2 2 2 4 4 4 0 Protein of unknown function (DUF3054) ATG13 PF10033.9 KFY05342.1 - 1.4e-70 237.7 0.0 3.6e-70 236.4 0.0 1.6 2 0 0 2 2 2 1 Autophagy-related protein 13 RCC1 PF00415.18 KFY05343.1 - 3.2e-22 78.9 0.3 0.00039 21.0 0.0 5.3 5 0 0 5 5 5 4 Regulator of chromosome condensation (RCC1) repeat BTB PF00651.31 KFY05343.1 - 5.1e-11 42.8 0.0 1.6e-05 25.1 0.0 2.5 2 0 0 2 2 2 2 BTB/POZ domain Ank_4 PF13637.6 KFY05343.1 - 1.2e-10 41.7 0.0 2.1e-05 25.0 0.0 2.6 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 KFY05343.1 - 1.1e-07 31.5 0.0 0.021 15.3 0.0 3.3 2 0 0 2 2 2 2 Ankyrin repeat Ank_2 PF12796.7 KFY05343.1 - 1.9e-07 31.6 0.0 5.6e-07 30.1 0.0 1.8 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) RCC1_2 PF13540.6 KFY05343.1 - 2.1e-05 24.2 5.1 0.0002 21.1 3.4 3.0 2 0 0 2 2 2 1 Regulator of chromosome condensation (RCC1) repeat Ank_5 PF13857.6 KFY05343.1 - 0.00039 20.7 0.0 0.013 15.8 0.0 2.7 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 KFY05343.1 - 0.00049 20.4 0.0 0.068 13.7 0.0 2.9 2 0 0 2 2 2 1 Ankyrin repeat RHD_DNA_bind PF00554.22 KFY05343.1 - 0.12 12.3 0.4 0.88 9.5 0.0 2.6 3 0 0 3 3 3 0 Rel homology DNA-binding domain Glyco_hydro_76 PF03663.14 KFY05344.1 - 1.1e-150 502.3 18.3 1.3e-150 502.0 18.3 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Glyco_hydro_88 PF07470.13 KFY05344.1 - 0.0021 17.2 9.3 0.33 10.0 0.1 3.2 2 1 1 3 3 3 3 Glycosyl Hydrolase Family 88 Glyco_hydro_30 PF02055.16 KFY05345.1 - 2.6e-18 66.1 0.2 3.5e-18 65.7 0.2 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 30 TIM-barrel domain Glyco_hydro_30C PF17189.4 KFY05345.1 - 3.1e-06 27.3 0.8 6.2e-06 26.3 0.8 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 30 beta sandwich domain Glyco_hydro_59 PF02057.15 KFY05345.1 - 0.0016 17.8 1.0 0.0034 16.7 1.0 1.6 1 1 0 1 1 1 1 Glycosyl hydrolase family 59 Glyco_hydr_30_2 PF14587.6 KFY05345.1 - 0.052 13.1 0.0 0.1 12.2 0.0 1.4 1 0 0 1 1 1 0 O-Glycosyl hydrolase family 30 Tube PF17212.3 KFY05345.1 - 0.14 12.2 0.0 0.25 11.4 0.0 1.3 1 0 0 1 1 1 0 Tail tubular protein MIP PF00230.20 KFY05346.1 - 1e-28 100.6 8.7 1.7e-28 99.9 8.7 1.4 1 1 0 1 1 1 1 Major intrinsic protein ABC_tran PF00005.27 KFY05347.1 - 1.2e-47 161.8 0.1 6.3e-28 98.0 0.0 2.5 2 0 0 2 2 2 2 ABC transporter ABC2_membrane_3 PF12698.7 KFY05347.1 - 3.5e-23 82.3 49.1 5e-19 68.6 13.0 3.0 2 1 0 2 2 2 2 ABC-2 family transporter protein AAA_21 PF13304.6 KFY05347.1 - 3.6e-19 69.7 0.7 3.8e-05 23.6 0.0 4.4 4 0 0 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 KFY05347.1 - 2.4e-07 30.4 1.6 6.4e-05 22.5 0.0 3.5 2 2 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_30 PF13604.6 KFY05347.1 - 1.6e-05 24.7 0.2 0.099 12.3 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_15 PF13175.6 KFY05347.1 - 1.8e-05 24.7 0.6 1 9.0 0.0 3.4 3 0 0 3 3 3 2 AAA ATPase domain AAA_23 PF13476.6 KFY05347.1 - 3.4e-05 24.4 3.8 0.11 13.0 0.1 2.6 3 0 0 3 3 2 2 AAA domain AAA_29 PF13555.6 KFY05347.1 - 6.2e-05 22.7 0.6 0.43 10.4 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_19 PF13245.6 KFY05347.1 - 0.00035 20.9 1.2 0.25 11.6 0.0 2.7 2 1 0 2 2 2 2 AAA domain ABC2_membrane PF01061.24 KFY05347.1 - 0.00049 19.6 13.5 0.00049 19.6 13.5 3.8 3 0 0 3 3 2 1 ABC-2 type transporter RsgA_GTPase PF03193.16 KFY05347.1 - 0.0009 19.2 0.3 0.11 12.4 0.1 2.5 2 0 0 2 2 2 1 RsgA GTPase AAA_16 PF13191.6 KFY05347.1 - 0.0022 18.4 0.1 3.4 8.0 0.0 2.7 2 0 0 2 2 2 2 AAA ATPase domain RNA_helicase PF00910.22 KFY05347.1 - 0.011 16.1 0.0 0.94 9.9 0.0 2.7 2 0 0 2 2 2 0 RNA helicase AAA PF00004.29 KFY05347.1 - 0.011 16.1 0.3 2.9 8.3 0.1 2.9 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_11 PF13086.6 KFY05347.1 - 0.019 14.8 0.7 4.7 6.9 0.0 3.0 2 1 1 3 3 3 0 AAA domain IstB_IS21 PF01695.17 KFY05347.1 - 0.04 13.7 0.6 56 3.4 0.0 4.0 4 0 0 4 4 4 0 IstB-like ATP binding protein Rad17 PF03215.15 KFY05347.1 - 0.041 13.8 0.0 3.5 7.5 0.0 2.4 2 0 0 2 2 2 0 Rad17 P-loop domain MukB PF04310.12 KFY05347.1 - 0.046 13.5 0.9 7.9 6.2 0.0 2.8 2 0 0 2 2 2 0 MukB N-terminal AAA_22 PF13401.6 KFY05347.1 - 0.06 13.6 1.3 10 6.4 0.3 3.1 2 2 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 KFY05347.1 - 0.079 12.2 0.0 0.63 9.3 0.0 2.2 2 0 0 2 2 2 0 Zeta toxin G6B PF15096.6 KFY05347.1 - 0.1 12.3 0.0 0.25 11.1 0.0 1.6 1 0 0 1 1 1 0 G6B family AAA_28 PF13521.6 KFY05347.1 - 0.27 11.4 1.0 13 6.0 0.0 2.6 2 0 0 2 2 2 0 AAA domain SRP54 PF00448.22 KFY05347.1 - 0.31 10.6 4.7 1.9 8.1 0.4 2.7 3 0 0 3 3 3 0 SRP54-type protein, GTPase domain DUF726 PF05277.12 KFY05348.1 - 5.9e-126 420.0 3.2 8.8e-126 419.4 3.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF726) Pkinase PF00069.25 KFY05348.1 - 1.8e-16 60.3 0.0 7.4e-16 58.3 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 KFY05348.1 - 1.3e-12 47.6 0.0 4.1e-12 45.9 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 KFY05348.1 - 0.0091 15.3 0.0 0.016 14.5 0.0 1.3 1 0 0 1 1 1 1 Kinase-like UPF0565 PF10561.9 KFY05348.1 - 0.08 12.1 0.0 0.21 10.8 0.0 1.8 1 0 0 1 1 1 0 Uncharacterised protein family UPF0565 EamA PF00892.20 KFY05351.1 - 0.00023 21.3 16.8 0.0015 18.7 16.8 2.0 1 1 0 1 1 1 1 EamA-like transporter family TMEM234 PF10639.9 KFY05351.1 - 0.065 13.3 1.8 0.091 12.8 1.3 1.4 1 1 0 1 1 1 0 Putative transmembrane family 234 Voltage_CLC PF00654.20 KFY05352.1 - 7.2e-88 295.2 25.9 7.2e-88 295.2 25.9 1.6 2 0 0 2 2 2 1 Voltage gated chloride channel CBS PF00571.28 KFY05352.1 - 8.5e-14 51.8 0.1 1.2e-05 25.7 0.0 2.6 2 0 0 2 2 2 2 CBS domain CBFD_NFYB_HMF PF00808.23 KFY05354.1 - 7.4e-11 42.2 0.2 5.3e-10 39.4 0.0 2.1 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone DUF1844 PF08899.11 KFY05354.1 - 0.11 12.9 0.0 0.21 11.9 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1844) DUF4611 PF15387.6 KFY05354.1 - 1.3 9.3 6.0 27 5.1 3.5 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4611) MoCF_biosynth PF00994.24 KFY05355.1 - 3.2e-54 182.5 0.2 7.9e-26 90.4 0.1 2.4 2 0 0 2 2 2 2 Probable molybdopterin binding domain MoeA_N PF03453.17 KFY05355.1 - 6e-37 126.8 1.0 1e-36 126.1 1.0 1.4 1 0 0 1 1 1 1 MoeA N-terminal region (domain I and II) MoeA_C PF03454.15 KFY05355.1 - 4.2e-16 58.9 0.8 1.4e-15 57.2 0.0 2.4 3 0 0 3 3 3 1 MoeA C-terminal region (domain IV) WD40 PF00400.32 KFY05355.1 - 2.9e-09 37.4 1.7 0.28 12.1 0.3 5.8 4 0 0 4 4 4 2 WD domain, G-beta repeat Keratin_2_head PF16208.5 KFY05355.1 - 0.042 14.0 1.0 0.1 12.7 1.0 1.6 1 0 0 1 1 1 0 Keratin type II head ANAPC4_WD40 PF12894.7 KFY05355.1 - 0.13 12.6 0.0 9.4 6.6 0.0 3.3 3 1 1 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain Vta1_C PF18097.1 KFY05355.1 - 0.29 10.9 0.7 16 5.3 0.1 3.3 3 0 0 3 3 3 0 Vta1 C-terminal domain ATP_bind_1 PF03029.17 KFY05356.1 - 1.4e-74 250.9 0.0 1.4e-74 250.9 0.0 1.6 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein MeaB PF03308.16 KFY05356.1 - 0.0014 17.7 0.0 0.0032 16.5 0.0 1.5 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_31 PF13614.6 KFY05356.1 - 0.0041 17.1 0.0 0.89 9.4 0.0 2.3 1 1 1 2 2 2 2 AAA domain AAA_10 PF12846.7 KFY05356.1 - 0.011 14.7 0.0 0.016 14.1 0.0 1.2 1 0 0 1 1 1 0 AAA-like domain AAA_29 PF13555.6 KFY05356.1 - 0.012 15.3 0.0 0.027 14.2 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_30 PF13604.6 KFY05356.1 - 0.041 13.6 0.3 0.12 12.1 0.0 1.9 2 1 0 2 2 2 0 AAA domain AAA_18 PF13238.6 KFY05356.1 - 0.078 13.5 0.1 0.84 10.2 0.0 2.3 2 0 0 2 2 2 0 AAA domain RNase_P_Rpp14 PF01900.19 KFY05357.1 - 8.1e-39 132.0 0.0 1.1e-38 131.6 0.0 1.2 1 0 0 1 1 1 1 Rpp14/Pop5 family Chitin_bind_1 PF00187.19 KFY05359.1 - 1.5e-07 31.8 19.7 2.3e-07 31.2 19.1 1.7 1 1 0 1 1 1 1 Chitin recognition protein Methyltransf_25 PF13649.6 KFY05361.1 - 2.7e-14 53.6 0.0 5.8e-14 52.6 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 KFY05361.1 - 1e-13 51.7 0.0 2.6e-13 50.4 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 KFY05361.1 - 1e-08 35.1 0.0 1.4e-08 34.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 KFY05361.1 - 1.3e-08 35.5 0.0 2e-08 34.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 KFY05361.1 - 0.00034 20.5 0.0 0.00048 20.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 KFY05361.1 - 0.00049 19.5 0.0 0.0014 18.0 0.0 1.7 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family PRMT5 PF05185.16 KFY05361.1 - 0.045 13.6 0.0 0.061 13.2 0.0 1.2 1 0 0 1 1 1 0 PRMT5 arginine-N-methyltransferase Methyltransf_28 PF02636.17 KFY05361.1 - 0.048 13.3 0.0 0.053 13.1 0.0 1.2 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase Cupin_2 PF07883.11 KFY05362.1 - 1e-06 28.3 0.0 2.8e-06 27.0 0.0 1.7 2 0 0 2 2 2 1 Cupin domain Cupin_3 PF05899.12 KFY05362.1 - 0.0013 18.3 0.0 0.0023 17.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF861) His_Phos_1 PF00300.22 KFY05363.1 - 1e-15 58.0 0.0 1.9e-15 57.1 0.0 1.4 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) His_Phos_2 PF00328.22 KFY05364.1 - 1.1e-15 57.9 0.0 1.3e-09 37.9 0.0 2.3 1 1 0 2 2 2 2 Histidine phosphatase superfamily (branch 2) zf-CCHC_5 PF14787.6 KFY05364.1 - 0.15 11.8 0.1 0.47 10.2 0.1 1.8 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger PPR_2 PF13041.6 KFY05365.1 - 3.2e-29 100.9 0.0 2.9e-08 33.8 0.0 8.7 8 1 1 9 9 9 5 PPR repeat family PPR_3 PF13812.6 KFY05365.1 - 8e-18 64.3 0.2 6.6e-07 29.3 0.0 6.5 4 3 2 7 7 7 4 Pentatricopeptide repeat domain PPR PF01535.20 KFY05365.1 - 6.5e-14 51.1 0.4 0.012 15.9 0.1 7.0 8 0 0 8 8 8 2 PPR repeat PPR_1 PF12854.7 KFY05365.1 - 3.2e-12 45.9 0.4 0.085 12.6 0.1 8.2 10 0 0 10 10 10 3 PPR repeat PPR_long PF17177.4 KFY05365.1 - 8.2e-06 25.3 0.0 0.00014 21.3 0.0 3.0 4 0 0 4 4 4 1 Pentacotripeptide-repeat region of PRORP ATP13 PF12921.7 KFY05365.1 - 0.029 14.2 0.0 25 4.8 0.0 4.9 5 1 0 5 5 5 0 Mitochondrial ATPase expression RPM2 PF08579.11 KFY05365.1 - 0.038 14.4 0.1 0.35 11.3 0.3 2.5 2 0 0 2 2 2 0 Mitochondrial ribonuclease P subunit (RPM2) Vps39_2 PF10367.9 KFY05365.1 - 0.14 12.6 0.4 0.37 11.3 0.0 1.9 2 0 0 2 2 2 0 Vacuolar sorting protein 39 domain 2 Mis12 PF05859.12 KFY05366.1 - 7.6e-41 139.3 0.0 1.2e-40 138.7 0.0 1.3 1 0 0 1 1 1 1 Mis12 protein CHAP PF05257.16 KFY05367.1 - 0.0066 17.0 0.8 0.016 15.7 0.2 2.1 2 1 0 2 2 2 1 CHAP domain AIM3 PF17096.5 KFY05367.1 - 0.036 15.0 0.2 0.036 15.0 0.2 5.6 6 0 0 6 6 6 0 Altered inheritance of mitochondria protein 3 Lactamase_B_4 PF13691.6 KFY05370.1 - 1.2e-27 95.3 0.1 6e-27 93.1 0.1 2.1 2 0 0 2 2 2 1 tRNase Z endonuclease Lactamase_B_2 PF12706.7 KFY05370.1 - 2.5e-13 50.0 0.0 5.5e-13 48.9 0.0 1.6 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 KFY05370.1 - 0.076 13.0 0.0 0.22 11.5 0.0 1.8 1 0 0 1 1 1 0 Metallo-beta-lactamase superfamily TCTP PF00838.17 KFY05371.1 - 2.8e-71 239.2 4.6 3.1e-71 239.1 4.6 1.0 1 0 0 1 1 1 1 Translationally controlled tumour protein S4 PF01479.25 KFY05371.1 - 0.01 15.5 0.2 0.3 10.8 0.1 2.5 1 1 1 2 2 2 0 S4 domain FA_hydroxylase PF04116.13 KFY05372.1 - 4.6e-23 82.0 11.1 4.6e-23 82.0 11.1 2.1 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily DUF3606 PF12244.8 KFY05372.1 - 0.099 12.6 0.0 0.24 11.4 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3606) Transport_MerF PF11431.8 KFY05372.1 - 0.25 11.3 2.5 2.3 8.1 0.6 2.6 2 0 0 2 2 2 0 Membrane transport protein MerF AMPK1_CBM PF16561.5 KFY05373.1 - 0.024 14.9 0.1 0.097 12.9 0.0 1.9 2 0 0 2 2 2 0 Glycogen recognition site of AMP-activated protein kinase Mtc PF03820.17 KFY05374.1 - 1.4e-94 316.7 0.1 1.6e-94 316.4 0.1 1.0 1 0 0 1 1 1 1 Tricarboxylate carrier Osw5 PF17062.5 KFY05374.1 - 0.99 9.5 3.1 1.6 8.9 0.1 2.2 2 0 0 2 2 2 0 Outer spore wall 5 UEV PF05743.13 KFY05378.1 - 2.7e-37 127.3 0.0 3.9e-37 126.8 0.0 1.2 1 0 0 1 1 1 1 UEV domain RNA_pol_Rpb2_6 PF00562.28 KFY05379.1 - 4.8e-123 411.1 0.1 8.7e-123 410.2 0.1 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 KFY05379.1 - 1.5e-59 201.0 0.0 4.7e-59 199.3 0.0 1.8 1 1 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.14 KFY05379.1 - 4.6e-49 166.6 0.0 9.2e-49 165.7 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_3 PF04565.16 KFY05379.1 - 1.1e-25 89.5 0.1 2.6e-25 88.4 0.1 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_4 PF04566.13 KFY05379.1 - 3.6e-24 84.8 1.1 6.9e-24 83.9 0.4 2.0 2 0 0 2 2 1 1 RNA polymerase Rpb2, domain 4 ADH_N PF08240.12 KFY05379.1 - 8.7e-24 83.5 3.7 4.1e-23 81.3 4.0 2.0 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain RNA_pol_Rpb2_5 PF04567.17 KFY05379.1 - 1.4e-21 76.8 0.1 3.4e-21 75.5 0.1 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 ADH_zinc_N PF00107.26 KFY05379.1 - 2.2e-18 66.5 0.0 5.1e-18 65.3 0.0 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 KFY05379.1 - 3e-08 34.8 0.0 7e-08 33.6 0.0 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 KFY05379.1 - 0.019 14.3 0.1 0.038 13.4 0.1 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain RNA_pol_Rpb2_7 PF04560.20 KFY05379.1 - 0.027 14.9 0.0 0.072 13.5 0.0 1.7 1 0 0 1 1 1 0 RNA polymerase Rpb2, domain 7 PET117 PF15786.5 KFY05380.1 - 2.1e-25 88.8 2.1 2.4e-25 88.6 2.1 1.0 1 0 0 1 1 1 1 PET assembly of cytochrome c oxidase, mitochondrial V-ATPase_G PF03179.15 KFY05381.1 - 1.8e-32 112.0 15.4 2.1e-32 111.8 15.4 1.0 1 0 0 1 1 1 1 Vacuolar (H+)-ATPase G subunit ATP-synt_B PF00430.18 KFY05381.1 - 0.0038 17.3 18.7 0.0064 16.6 9.2 2.0 1 1 1 2 2 2 1 ATP synthase B/B' CF(0) V-ATPase_G_2 PF16999.5 KFY05381.1 - 0.015 15.7 14.2 0.024 15.0 14.2 1.4 1 1 0 1 1 1 0 Vacuolar (H+)-ATPase G subunit DUF1834 PF08873.11 KFY05381.1 - 0.053 13.3 0.9 0.073 12.8 0.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1834) DUF3552 PF12072.8 KFY05381.1 - 0.13 11.7 19.6 0.025 14.0 12.5 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF3552) PNISR PF15996.5 KFY05381.1 - 0.17 12.2 11.8 0.18 12.0 11.8 1.1 1 0 0 1 1 1 0 Arginine/serine-rich protein PNISR DUF2203 PF09969.9 KFY05381.1 - 0.24 12.1 4.9 0.33 11.7 4.9 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2203) ATP11 PF06644.11 KFY05381.1 - 0.33 10.7 10.7 0.41 10.4 10.7 1.0 1 0 0 1 1 1 0 ATP11 protein RRF PF01765.19 KFY05381.1 - 0.47 10.4 13.7 0.54 10.2 12.7 1.7 1 1 1 2 2 2 0 Ribosome recycling factor HOIP-UBA PF16678.5 KFY05381.1 - 0.49 10.4 6.5 0.98 9.4 6.6 1.4 1 1 0 1 1 1 0 HOIP UBA domain pair Atrophin-1 PF03154.15 KFY05381.1 - 1.2 7.3 6.3 1.2 7.3 6.3 1.0 1 0 0 1 1 1 0 Atrophin-1 family Atg14 PF10186.9 KFY05381.1 - 3.3 6.7 8.0 3.5 6.6 8.0 1.0 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 vATP-synt_E PF01991.18 KFY05381.1 - 4.8 6.5 18.7 71 2.7 18.8 2.0 1 1 0 1 1 1 0 ATP synthase (E/31 kDa) subunit DUF4407 PF14362.6 KFY05381.1 - 5 6.4 8.8 5.4 6.3 8.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Palm_thioest PF02089.15 KFY05382.1 - 4.8e-06 26.6 0.0 1.3e-05 25.2 0.0 1.6 1 1 1 2 2 2 1 Palmitoyl protein thioesterase DUF676 PF05057.14 KFY05382.1 - 6.5e-06 25.8 0.0 1.2e-05 25.0 0.0 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) PGAP1 PF07819.13 KFY05382.1 - 1.5e-05 24.9 0.0 2.3e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein LCAT PF02450.15 KFY05382.1 - 0.00043 19.6 0.0 0.00074 18.8 0.0 1.3 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase Abhydrolase_1 PF00561.20 KFY05382.1 - 0.0024 17.6 0.0 0.43 10.2 0.0 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold DUF900 PF05990.12 KFY05382.1 - 0.012 15.2 0.0 0.018 14.6 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) Abhydrolase_6 PF12697.7 KFY05382.1 - 0.033 14.8 0.1 0.12 13.0 0.0 1.9 1 1 1 2 2 2 0 Alpha/beta hydrolase family Lipase_2 PF01674.18 KFY05382.1 - 0.12 11.9 0.0 0.27 10.7 0.0 1.5 1 0 0 1 1 1 0 Lipase (class 2) Arrestin_N PF00339.29 KFY05383.1 - 1.1e-13 51.4 0.1 3.2e-09 37.0 0.0 3.0 3 0 0 3 3 3 2 Arrestin (or S-antigen), N-terminal domain p47_phox_C PF08944.11 KFY05383.1 - 0.06 12.8 1.0 0.15 11.5 1.0 1.6 1 0 0 1 1 1 0 NADPH oxidase subunit p47Phox, C terminal domain RPA43_OB PF17875.1 KFY05385.1 - 1.5e-29 103.1 0.6 1.5e-29 103.1 0.6 4.1 2 2 0 2 2 2 1 RPA43 OB domain in RNA Pol I SHS2_Rpb7-N PF03876.17 KFY05385.1 - 1e-07 32.2 0.0 1.9e-07 31.4 0.0 1.4 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 Zip PF02535.22 KFY05385.1 - 1.2 8.3 7.2 1.7 7.8 7.2 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter SOBP PF15279.6 KFY05385.1 - 1.8 9.1 5.9 2.4 8.7 5.9 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein CwsA PF10814.8 KFY05385.1 - 3.6 7.8 5.8 1.7 8.8 0.4 2.1 1 1 1 2 2 2 0 Cell wall synthesis protein CwsA DUF123 PF01986.16 KFY05388.1 - 0.032 14.7 0.0 0.14 12.7 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function DUF123 Sel1 PF08238.12 KFY05391.1 - 5e-13 49.3 18.9 4.5e-06 27.2 0.1 7.5 7 0 0 7 7 7 5 Sel1 repeat TBPIP PF07106.13 KFY05392.1 - 5.7e-14 51.8 0.0 1.2e-13 50.8 0.0 1.5 1 0 0 1 1 1 1 TBPIP/Hop2 winged helix domain SHOCT PF09851.9 KFY05392.1 - 0.018 14.8 2.7 3.4 7.5 0.1 3.0 3 0 0 3 3 3 0 Short C-terminal domain DUF3106 PF11304.8 KFY05392.1 - 0.041 14.4 5.1 1.7 9.2 3.4 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3106) PMI_typeI PF01238.21 KFY05395.1 - 2.7e-49 168.3 0.2 1e-44 153.3 0.1 3.0 1 1 1 2 2 2 2 Phosphomannose isomerase type I GFA PF04828.14 KFY05396.1 - 1.4e-19 70.2 0.2 2e-19 69.7 0.2 1.2 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme Ank_2 PF12796.7 KFY05398.1 - 1e-153 500.3 0.0 1e-18 67.7 0.0 10.2 2 2 9 11 11 11 11 Ankyrin repeats (3 copies) Ank_3 PF13606.6 KFY05398.1 - 8.7e-114 357.5 0.0 5e-05 23.4 0.0 17.9 18 0 0 18 18 18 17 Ankyrin repeat Ank PF00023.30 KFY05398.1 - 1.4e-106 344.7 0.0 8.8e-06 25.9 0.0 18.1 18 0 0 18 18 18 17 Ankyrin repeat Ank_4 PF13637.6 KFY05398.1 - 1.7e-101 331.4 0.0 1.7e-09 38.0 0.0 14.8 5 3 11 16 16 16 15 Ankyrin repeats (many copies) Ank_5 PF13857.6 KFY05398.1 - 3.9e-80 262.9 0.1 1.7e-06 28.2 0.0 16.5 3 2 14 17 17 17 16 Ankyrin repeats (many copies) PEGA PF08308.11 KFY05398.1 - 1.3e-17 63.5 0.0 0.65 9.9 0.0 13.4 13 3 3 16 16 16 2 PEGA domain HEM4 PF02602.15 KFY05398.1 - 3.3e-07 29.9 8.5 0.21 10.9 0.0 7.5 5 3 4 9 9 9 3 Uroporphyrinogen-III synthase HemD UDPG_MGDP_dh_C PF03720.15 KFY05398.1 - 3.8e-07 30.5 14.7 39 4.7 0.1 11.5 6 5 3 10 10 10 0 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain DUF4350 PF14258.6 KFY05398.1 - 2.9e-05 24.4 9.1 98 3.5 0.0 10.1 10 4 3 13 13 12 0 Domain of unknown function (DUF4350) RbpA PF13397.6 KFY05398.1 - 4.3e-05 24.1 6.8 2.8 8.6 0.1 6.2 3 2 4 7 7 7 1 RNA polymerase-binding protein TPR_21 PF09976.9 KFY05398.1 - 0.00041 20.1 11.7 2.1 8.0 0.1 6.5 3 2 2 7 7 7 2 Tetratricopeptide repeat-like domain DUF2442 PF10387.9 KFY05398.1 - 0.055 13.8 0.0 2.5e+02 2.0 0.0 5.4 5 2 1 6 6 5 0 Protein of unknown function (DUF2442) DUF498 PF04430.14 KFY05398.1 - 0.5 10.5 5.8 1.8e+02 2.2 0.0 7.2 9 2 3 12 12 12 0 Protein of unknown function (DUF498/DUF598) FliT PF05400.13 KFY05398.1 - 2 9.3 6.6 35 5.3 0.8 4.6 4 1 1 5 5 5 0 Flagellar protein FliT Amidinotransf PF02274.17 KFY05398.1 - 3.6 6.6 12.1 66 2.4 0.0 6.9 4 3 1 8 8 8 0 Amidinotransferase DUF433 PF04255.14 KFY05400.1 - 0.18 11.7 0.0 0.39 10.6 0.0 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF433) HMG_box PF00505.19 KFY05402.1 - 3e-13 50.0 0.0 8.1e-13 48.6 0.0 1.8 1 0 0 1 1 1 1 HMG (high mobility group) box CP2 PF04516.15 KFY05402.1 - 2.1e-10 40.3 0.1 3.8e-10 39.4 0.1 1.4 1 0 0 1 1 1 1 CP2 transcription factor SAM_1 PF00536.30 KFY05402.1 - 3.8e-10 40.1 0.0 7.5e-10 39.1 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) HMG_box_2 PF09011.10 KFY05402.1 - 7.6e-09 36.0 0.0 2.4e-08 34.5 0.0 1.9 1 0 0 1 1 1 1 HMG-box domain SAM_2 PF07647.17 KFY05402.1 - 6.9e-08 32.5 0.2 2.7e-07 30.6 0.1 2.0 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) Ecl1 PF12855.7 KFY05403.1 - 5.9e-11 43.8 1.1 6.9e-11 43.6 1.1 1.1 1 0 0 1 1 1 1 ECL1/2/3 zinc binding proteins YacG PF03884.14 KFY05403.1 - 0.38 10.5 6.0 1.1 9.0 5.9 1.8 1 1 1 2 2 2 0 DNA gyrase inhibitor YacG zf-FLZ PF04570.14 KFY05403.1 - 0.78 9.3 6.4 18 4.9 2.8 2.3 1 1 1 2 2 2 0 zinc-finger of the FCS-type, C2-C2 Zn_clus PF00172.18 KFY05406.1 - 1.4e-07 31.5 9.5 2.9e-07 30.5 9.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 KFY05406.1 - 3.8e-06 26.1 0.8 7.1e-06 25.2 0.1 1.8 2 0 0 2 2 2 1 Fungal specific transcription factor domain Fungal_trans PF04082.18 KFY05407.1 - 1.9e-07 30.4 0.3 2.9e-07 29.8 0.3 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KFY05407.1 - 4.6e-05 23.4 10.3 4.6e-05 23.4 10.3 2.0 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF4342 PF14242.6 KFY05407.1 - 0.15 12.1 0.0 0.29 11.1 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4342) HMG_box PF00505.19 KFY05408.1 - 2.3e-13 50.4 1.0 4.7e-13 49.3 1.0 1.6 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 KFY05408.1 - 8.7e-12 45.5 1.6 1.9e-11 44.4 1.6 1.5 1 0 0 1 1 1 1 HMG-box domain Fungal_trans PF04082.18 KFY05408.1 - 1.2e-11 44.1 0.0 2.3e-11 43.2 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain SAM_1 PF00536.30 KFY05408.1 - 1.9e-10 41.0 0.1 4.2e-10 39.9 0.1 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 KFY05408.1 - 1.6e-07 31.4 0.1 3.1e-07 30.4 0.1 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Ins_allergen_rp PF06757.13 KFY05408.1 - 0.16 11.9 2.8 0.45 10.5 2.8 1.6 1 1 0 1 1 1 0 Insect allergen related repeat, nitrile-specifier detoxification AA_permease_2 PF13520.6 KFY05412.1 - 0.00089 18.2 1.3 0.0011 17.9 1.3 1.1 1 0 0 1 1 1 1 Amino acid permease Vma12 PF11712.8 KFY05412.1 - 0.0082 16.2 0.6 0.013 15.6 0.2 1.4 1 1 0 1 1 1 1 Endoplasmic reticulum-based factor for assembly of V-ATPase DsbD_2 PF13386.6 KFY05412.1 - 0.0082 16.1 0.9 0.015 15.2 0.9 1.3 1 0 0 1 1 1 1 Cytochrome C biogenesis protein transmembrane region NDUF_B12 PF08122.12 KFY05412.1 - 0.078 13.0 1.9 7.2 6.7 0.1 2.5 2 1 0 2 2 2 0 NADH-ubiquinone oxidoreductase B12 subunit family FAD_binding_3 PF01494.19 KFY05414.1 - 1.2e-20 74.1 0.3 4.5e-20 72.2 0.3 1.8 1 1 0 1 1 1 1 FAD binding domain FAD_binding_2 PF00890.24 KFY05414.1 - 1.3e-08 34.4 0.3 2.2e-08 33.6 0.3 1.4 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 KFY05414.1 - 1.4e-07 31.6 0.1 3.5e-07 30.3 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 KFY05414.1 - 5.6e-07 29.1 0.6 7.1e-06 25.5 0.2 2.0 1 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 KFY05414.1 - 2.8e-06 27.2 0.2 4.3e-05 23.2 0.1 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 KFY05414.1 - 1.7e-05 25.3 0.3 0.00011 22.7 0.1 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 KFY05414.1 - 7.9e-05 22.0 0.3 0.00014 21.2 0.3 1.5 1 1 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain GIDA PF01134.22 KFY05414.1 - 0.00012 21.3 0.1 0.00014 21.0 0.1 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A HI0933_like PF03486.14 KFY05414.1 - 0.00016 20.6 0.2 0.00025 19.9 0.2 1.3 1 0 0 1 1 1 1 HI0933-like protein Amino_oxidase PF01593.24 KFY05414.1 - 0.0011 18.4 0.1 0.0021 17.4 0.1 1.4 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase ApbA PF02558.16 KFY05414.1 - 0.0014 18.3 0.0 0.0097 15.6 0.0 2.1 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA Pyr_redox_3 PF13738.6 KFY05414.1 - 0.0023 17.2 0.0 0.0039 16.5 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 KFY05414.1 - 0.0049 16.1 0.1 0.0086 15.3 0.1 1.3 1 0 0 1 1 1 1 Thi4 family FAD_oxidored PF12831.7 KFY05414.1 - 0.0079 15.6 0.1 0.0079 15.6 0.1 1.5 2 0 0 2 2 2 1 FAD dependent oxidoreductase Trp_halogenase PF04820.14 KFY05414.1 - 0.0081 15.1 0.3 0.056 12.3 0.1 2.2 2 0 0 2 2 2 1 Tryptophan halogenase 3HCDH_N PF02737.18 KFY05414.1 - 0.016 15.1 0.2 0.031 14.2 0.2 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.14 KFY05414.1 - 0.016 14.8 0.0 0.031 13.8 0.0 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain TrkA_N PF02254.18 KFY05414.1 - 0.025 14.8 0.0 0.062 13.6 0.0 1.7 1 0 0 1 1 1 0 TrkA-N domain Lycopene_cycl PF05834.12 KFY05414.1 - 0.033 13.3 0.1 0.033 13.3 0.1 2.0 3 0 0 3 3 3 0 Lycopene cyclase protein NAD_binding_7 PF13241.6 KFY05414.1 - 0.075 13.5 0.0 0.13 12.7 0.0 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding p450 PF00067.22 KFY05415.1 - 4.4e-50 170.8 0.0 5.7e-50 170.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 FMO-like PF00743.19 KFY05416.1 - 7.4e-13 47.7 0.0 1.5e-11 43.5 0.0 2.3 3 0 0 3 3 3 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 KFY05416.1 - 3.5e-12 46.2 0.0 8.4e-12 45.0 0.0 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 KFY05416.1 - 7e-11 41.9 0.0 1.6e-09 37.4 0.0 2.3 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 KFY05416.1 - 5.8e-09 36.1 0.0 1.5e-07 31.5 0.0 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 KFY05416.1 - 6.9e-08 32.0 0.0 1.4e-06 27.8 0.0 2.4 2 0 0 2 2 2 1 Thi4 family K_oxygenase PF13434.6 KFY05416.1 - 0.00023 20.4 0.0 0.026 13.7 0.0 2.6 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.24 KFY05416.1 - 0.00032 20.4 0.4 0.0029 17.2 0.2 2.4 2 1 0 3 3 3 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 KFY05416.1 - 0.00096 19.7 0.1 0.25 12.0 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 KFY05416.1 - 0.015 14.4 0.7 0.52 9.3 0.1 2.1 2 0 0 2 2 2 0 Glucose inhibited division protein A Lycopene_cycl PF05834.12 KFY05416.1 - 0.022 13.8 0.1 0.58 9.1 0.0 2.8 3 0 0 3 3 3 0 Lycopene cyclase protein NAD_binding_9 PF13454.6 KFY05416.1 - 0.033 14.2 0.8 5.5 7.0 0.0 3.5 4 0 0 4 4 4 0 FAD-NAD(P)-binding FAD_binding_2 PF00890.24 KFY05416.1 - 0.034 13.3 0.0 0.062 12.4 0.0 1.4 1 0 0 1 1 1 0 FAD binding domain DUF1344 PF07076.11 KFY05416.1 - 0.081 12.9 0.1 0.17 11.8 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1344) FAD_oxidored PF12831.7 KFY05416.1 - 0.17 11.2 0.0 0.29 10.4 0.0 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase HI0933_like PF03486.14 KFY05416.1 - 0.2 10.3 0.3 0.43 9.2 0.1 1.6 2 0 0 2 2 2 0 HI0933-like protein efThoc1 PF11957.8 KFY05417.1 - 4.9e-149 497.1 0.2 7.1e-149 496.6 0.2 1.2 1 0 0 1 1 1 1 THO complex subunit 1 transcription elongation factor Guanylate_kin PF00625.21 KFY05417.1 - 1.9e-47 161.3 0.0 3.1e-47 160.6 0.0 1.4 1 0 0 1 1 1 1 Guanylate kinase AAA_18 PF13238.6 KFY05417.1 - 4.5e-05 24.0 0.1 0.00019 21.9 0.0 2.2 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.23 KFY05417.1 - 0.011 15.8 0.0 0.046 13.8 0.0 2.2 1 1 0 1 1 1 0 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 KFY05417.1 - 0.028 14.3 0.0 0.067 13.1 0.0 1.6 1 0 0 1 1 1 0 RsgA GTPase dNK PF01712.19 KFY05417.1 - 0.098 12.5 1.3 3.3 7.5 0.1 2.8 2 1 0 2 2 2 0 Deoxynucleoside kinase Aquarius_N PF16399.5 KFY05418.1 - 0 1126.9 0.0 0 1126.5 0.0 1.1 1 0 0 1 1 1 1 Intron-binding protein aquarius N-terminus AAA_12 PF13087.6 KFY05418.1 - 1.6e-26 93.2 0.0 2.9e-26 92.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 KFY05418.1 - 3.4e-22 79.5 0.0 5.8e-21 75.4 0.0 2.3 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 KFY05418.1 - 1.6e-08 34.5 0.0 0.0012 18.6 0.0 2.5 2 0 0 2 2 2 2 AAA domain ResIII PF04851.15 KFY05418.1 - 1.2e-05 25.4 0.0 3.1e-05 24.1 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_19 PF13245.6 KFY05418.1 - 1.2e-05 25.7 0.0 2.7e-05 24.5 0.0 1.7 1 1 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.18 KFY05418.1 - 0.00017 21.4 0.6 0.0083 15.9 0.1 3.1 4 0 0 4 4 4 1 Viral (Superfamily 1) RNA helicase DnaB_C PF03796.15 KFY05418.1 - 0.001 18.4 0.0 0.0021 17.4 0.0 1.4 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain AAA_16 PF13191.6 KFY05418.1 - 0.0019 18.6 0.0 0.011 16.1 0.0 2.4 2 0 0 2 2 1 1 AAA ATPase domain UvrD_C_2 PF13538.6 KFY05418.1 - 0.0024 17.7 0.2 0.0074 16.1 0.2 1.9 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA PF00004.29 KFY05418.1 - 0.0024 18.3 0.0 0.006 17.0 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DUF2075 PF09848.9 KFY05418.1 - 0.014 14.7 0.9 0.027 13.7 0.0 1.8 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA_22 PF13401.6 KFY05418.1 - 0.017 15.4 0.2 0.12 12.7 0.1 2.4 1 1 1 2 2 2 0 AAA domain NB-ARC PF00931.22 KFY05418.1 - 0.077 12.2 0.0 0.18 11.0 0.0 1.5 1 0 0 1 1 1 0 NB-ARC domain Parvo_NS1 PF01057.17 KFY05418.1 - 0.087 11.9 0.0 0.14 11.2 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_5 PF07728.14 KFY05418.1 - 0.11 12.5 0.0 0.28 11.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Helicase_RecD PF05127.14 KFY05418.1 - 0.18 11.7 0.0 2.9 7.7 0.0 2.4 2 0 0 2 2 2 0 Helicase MIF4G PF02854.19 KFY05419.1 - 8.4e-51 172.6 0.0 1.4e-50 171.9 0.0 1.4 1 0 0 1 1 1 1 MIF4G domain eIF_4G1 PF12152.8 KFY05419.1 - 2.7e-23 81.9 1.4 7.8e-23 80.4 1.4 1.9 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 4G1 ABC2_membrane PF01061.24 KFY05420.1 - 7e-83 277.2 49.8 3.7e-48 163.7 19.4 2.5 2 0 0 2 2 2 2 ABC-2 type transporter ABC_tran PF00005.27 KFY05420.1 - 2.2e-34 118.9 0.1 1.2e-16 61.5 0.0 3.3 3 0 0 3 3 3 2 ABC transporter PDR_CDR PF06422.12 KFY05420.1 - 1.8e-27 95.0 6.1 1.1e-25 89.3 0.1 3.4 3 0 0 3 3 2 2 CDR ABC transporter ABC2_membrane_3 PF12698.7 KFY05420.1 - 9.6e-08 31.5 41.3 1.2e-06 27.9 17.2 2.4 2 0 0 2 2 2 2 ABC-2 family transporter protein ABC_trans_N PF14510.6 KFY05420.1 - 4.6e-06 27.1 0.3 1.8e-05 25.3 0.3 2.0 1 0 0 1 1 1 1 ABC-transporter N-terminal AAA_16 PF13191.6 KFY05420.1 - 0.00012 22.5 0.1 0.49 10.8 0.0 2.7 2 0 0 2 2 2 2 AAA ATPase domain RsgA_GTPase PF03193.16 KFY05420.1 - 0.00019 21.4 0.1 0.0011 18.9 0.0 2.1 2 0 0 2 2 2 1 RsgA GTPase AAA_33 PF13671.6 KFY05420.1 - 0.00046 20.4 0.1 0.73 10.0 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_21 PF13304.6 KFY05420.1 - 0.00071 19.5 0.4 0.53 10.0 0.0 2.7 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system DnaB_C PF03796.15 KFY05420.1 - 0.001 18.5 0.1 0.081 12.2 0.0 2.4 2 0 0 2 2 2 1 DnaB-like helicase C terminal domain AAA_29 PF13555.6 KFY05420.1 - 0.0028 17.3 2.6 0.083 12.6 0.2 3.3 3 0 0 3 3 3 1 P-loop containing region of AAA domain AAA_22 PF13401.6 KFY05420.1 - 0.0032 17.7 0.1 0.44 10.8 0.0 2.9 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.6 KFY05420.1 - 0.0036 16.9 0.0 0.019 14.5 0.1 2.0 2 0 0 2 2 2 1 AAA domain cobW PF02492.19 KFY05420.1 - 0.0053 16.4 0.1 0.16 11.5 0.0 2.3 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA PF00004.29 KFY05420.1 - 0.012 16.0 0.0 2.8 8.4 0.0 2.8 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.6 KFY05420.1 - 0.015 15.7 0.1 4.6 7.7 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 KFY05420.1 - 0.026 15.1 0.0 2.8 8.5 0.0 2.6 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 KFY05420.1 - 0.039 13.9 0.3 5.5 6.9 0.2 2.5 2 0 0 2 2 2 0 NACHT domain ATPase_2 PF01637.18 KFY05420.1 - 0.047 13.6 0.0 0.92 9.4 0.0 2.3 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea AAA_28 PF13521.6 KFY05420.1 - 0.16 12.2 0.1 0.49 10.6 0.1 1.8 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 KFY05420.1 - 0.19 11.4 1.7 5.9 6.6 0.3 2.5 2 0 0 2 2 2 0 AAA domain Fungal_trans PF04082.18 KFY05421.1 - 7.6e-13 48.1 0.3 1.4e-12 47.2 0.3 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 KFY05421.1 - 7.6e-07 29.2 9.7 1.7e-06 28.0 9.7 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain # # Program: hmmscan # Version: 3.2.1 (June 2018) # Pipeline mode: SCAN # Query file: /oak/stanford/groups/akundaje/marinovg/genomes/Fungi/Pseudogymnoascus_sp._VKM_F-3808-G1/GCA_000750675.1_DG1_protein.faa # Target file: /oak/stanford/groups/akundaje/marinovg/genomes/PFam/PFam32.0/Pfam-A.hmm # Option settings: /oak/stanford/groups/akundaje/marinovg/programs/hmmer-3.2.1/bin/hmmscan -o /oak/stanford/groups/akundaje/marinovg/genomes/Fungi/Pseudogymnoascus_sp._VKM_F-3808-G1/GCA_000750675.1_DG1_protein.PFam32-A --tblout /oak/stanford/groups/akundaje/marinovg/genomes/Fungi/Pseudogymnoascus_sp._VKM_F-3808-G1/GCA_000750675.1_DG1_protein.PFam32-A.tblout --cpu 20 /oak/stanford/groups/akundaje/marinovg/genomes/PFam/PFam32.0/Pfam-A.hmm /oak/stanford/groups/akundaje/marinovg/genomes/Fungi/Pseudogymnoascus_sp._VKM_F-3808-G1/GCA_000750675.1_DG1_protein.faa # Current dir: /oak/stanford/groups/akundaje/marinovg/genomes # Date: Mon Mar 25 04:09:42 2019 # [ok]